Curation_comments_temp,_to_do_,Record ID,PHI_MolConn_ID,IdentifierTypeOfProteinID,ProteinID,IdentifierTypeOfGeneLocusID,GeneLocusID,AA sequence #no EMBL#,NT sequence #no EMBL#,Genomic sequence providing strain,Gene_name,Genome location,Specific modification/s to the targeted protein or promoter,Accession ID for the modified genetic element,Known interacting protein(s) in the pathogen,Interacting protein - locus ID,Multiple_mutation,Pathogen_NCBI_species_Taxonomy ID,Pathogen_species,Pathogen_NCBI_strain_Taxonomy_ID,Experimental_strain,Disease_name,Host_descripton,Host_NCBI_Taxonomy_ID,Experimental_host_species,Host_strain_genotype_or cultivar_taxonomy_ID_NCBI,HostGenotype_definedGene of interest,HostGenotype_definedGene of interest _AccessionID,tissue_type,Function,GO_annotation,Database,Pathway_secretion_systems,Phenotype_of_mutant,Mating_defect_prior_to_penetration,Pre_penetration_defect,Penetration_defect,Post_penetration_defect,Disease_development_macroscopically_visible,Vegetative_spores,Sexual_spores,In_vitro_growth,Spore_germination,Essential_gene_Lethal_knockout,Inducer,ChemicalAccession (Chebi/CAS),Tested Host_target,TestedHostTarget_AccessionID,Interaction phenotype,Host_response,Experimental_evidence,Transient Assay Experimental Evidence,Species_Expert,Entered_by,Literature_ID,Literature_source,DOI,Full_citation,Author_email,Comments,Reference ,Year_published,Curation details,File_name_pdf_files_provided,_batch_no_,Curation date,_curator_organisation_,__lab__,__FG_mycotoxin__,Additional IdentifierTypeOfGeneLocusID,Additional GeneLocusID,Anti-infective (Chemical),Compound,Target site,Group name,Chemical group,Mode in planta,Mode of action ,FRAC CODE,Additional comments  on anti-infectives
Curation Comments,To do,Record ID,PHI_MolConn_ID,Protein ID source,Protein ID,Gene ID source,Gene ID,AA sequence,NT sequence,Sequence Strain,Gene,Chr location,Gene/Protein modification,Modified gene/protein Id,Interacting partner(s),Interacting partner(s) Id,Multiple mutation,Pathogen ID,Pathogen species,Pathogen strain ID,Pathogen strain,Disease,Host description,Host ID,Host species,Host strain,Host genotype,Host genotype-Id,Tissue,Gene Function,GO annotation,Database,Pathway,Mutant Phenotype,Mating defect,Prepenetration defect,Penetration defect,Postpenetration defect,Disease manifestation,Vegetative spores,Sexual spores,Invitro growth,Spore germination,Essential gene,Gene inducer,Gene inducer Id,Host target,Host target Id,Interaction phenotype,Host response,Exp. Technique-stable,Exp. Technique-transient,Species expert,Entered by,PMID,Ref. Source,DOI,Ref. detail,Author email,Comments,Author reference,Year,Curation details,File name,Batch no.,Curation date,Curator organization,Lab,FG-mycotoxin,AdditionalIdentifierTypeOfGeneLocusID,AdditionalGeneLocusID,Anti infective agent,Anti infective compound,Anti infective-target site,Anti infective group name,Anti infective Chemical group,Anti infective-Mode in planta,Mode of action,FRAC CODE,Anti infective-comments
,,Record 1,PHI:3,UniProt,P26215,EMBL,AAA79885,,,SB111,PGN1,,,,,,,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,endopolygalacturonase,GO:0004650,GO,,unaffected pathogenicity,,no,no,no,,,,,,,pectin,,,,,,gene disruption,,,MU; JA,2152162,PubMed,10.1105/tpc.2.12.1191,,,Expression during all infection stages. pathogen formerly called Cochliobolus carbonum teleomorph name,Scott-Craig et al.,1990,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 2,PHI:7,UniProt,P22287,EMBL,CAA42824,,,race 5,AVR9,,,,,,,5499,Fulvia fulva,,,leaf mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation; biochemical evidence,,,MU,1799694,PubMed,no data found,,,,Van Kan et al.,1991,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 3,PHI:12,UniProt,Q01886,EMBL,AAA33023,,,SB111,HTS1,,,,,,,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,cylic peptide synthase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB; JA,11607305,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,Panaccione et al.,1992,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 4,PHI:14,UniProt,P0C017,EMBL,AAB09711,,,clinical isolate,ADE2,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phosphoribosylaminoimidazole carboxylase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,12438649,PubMed,10.1073/pnas.232568599,,,,Perfect et al.,1993,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 5,PHI:14,UniProt,P0C017,EMBL,AAB09711,,,clinical isolate,ADE2,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,phosphoribosylaminoimidazole carboxylase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,12438649,PubMed,10.1073/pnas.232568599,,,,Perfect et al.,1993,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 6,PHI:15,UniProt,P52751,EMBL,AAA20128,,,Guy-11,MPG1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hydrophobin,"GO:0009405, IMP; GO:0051701",GO,,reduced virulence,,yes,,,,,,,,,,,,,,,gene deletion,,,MU,8312740,PubMed,10.1105/tpc.5.11.1575,,,,Talbot et al.,1993,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 7,PHI:17,UniProt,Q00663,EMBL,CAA43678,,,ATCC750,ACP,,,,,,,5482,Candida tropicalis,5482,ATCC 750,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,acid proteinase,"GO:0009405, IMP; GO:0004190",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,7983570,PubMed,no data found,,,,Togni et al.,1994,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 8,PHI:18,UniProt,Q00363,EMBL,CAA69643,,,Race 5,AVR4,,,,,,,5499,Fulvia fulva,,,leaf mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,biochemical analysis; gene mutation: characterised; gene complementation,,,TKB,8114941,PubMed,10.1038/367384a0,Nature 1994 Jan 27;367(6461):384-6,,Expression during biotrophic growth,Joosten et al,1994,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 9,PHI:19,UniProt,P34809,EMBL,AAA17547,,,L210425,NMT,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,myristoyl-CoA:protein N-myristoyltransferase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,heat sensitive,,,,,,,,,gene mutation: characterised,,,TKB; KHK,7991574,PubMed,no data found,,,Engineered temperature sensitive allele,Lodge et al.,1994,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 10,PHI:22,UniProt,P49606,EMBL,AAA57469,,,518,UAC1,,,,,,,5270,Ustilago maydis,,,smut (corn),monocots,4577,Zea mays (related: maize),,,,,adenylate cyclase,"GO:0009405, IMP",GO,cAMP signalling,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU,7995519,PubMed,no data found,,,,Gold et al.,1994,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 11,PHI:24,UniProt,Q00903,EMBL,AAB09777,,,,Avenacinase,,,,,,,29850,Gaeumannomyces graminis,29850,var. avenae strain A3,take-all,monocots,4564,Triticum (related: wheat),,,,,avenacinase,,,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption,,,MU,7824933,PubMed,no data found,,,Expression not determined,Bowyer et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 12,PHI:24,UniProt,Q00903,EMBL,AAB09777,,,,Avenacinase,,,,,,,29850,Gaeumannomyces graminis,29850,var. avenae strain A3,,monocots,4498,Avena sativa (related: oat),,,,,avenacinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,no,yes,yes,,,,,,,,,,,,,gene disruption,,,MU,7824933,PubMed,no data found,,,Expression not determined,Bowyer et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 13,PHI:25,UniProt,Q258K5,EMBL,CAJ29326,,,v23.1.3,AVRLM1,,,,,,,5022,Leptosphaeria maculans,,v23.1.3,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene disruption,,BH,TKB; AC,16556221,PubMed,10.1111/j.1365-2958.2006.05076.x,Gout et al. (2006) Mol. Microbiol. 60 (1); 67-80,rouxel@versailles.inra.fr,Functional complementation assay. Agro-mediated transformation of AvrLm1 into virulent strain restored avirulence.,Gout et al.,2006,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 14,PHI:26,UniProt,P28873,EMBL,CAA37820,,,B792,CaMDR1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,fungal efflux pump,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,7591094,PubMed,no data found,,,,Becker et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 15,PHI:27,UniProt,Q00368,EMBL,AAA77678,,,,CAP20,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,appressorial wall,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,,,,,,avocado surface wax,,,,,,gene disruption,,,TKB; JK,7756829,PubMed,10.1105/tpc.7.2.183,,,"Expression during host surface growth, invasion",Hwang et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 16,PHI:27,UniProt,Q00368,EMBL,AAA77678,,,,CAP20,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose,flowering plants,3435,Persea americana (related: avocado),,,,,appressorial wall,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,,,,,,avocado surface wax,,,,,,gene disruption,,,TKB; JK,7756829,PubMed,10.1105/tpc.7.2.183,,,"Tested on avocado fruits. Expression during host surface growth, invasion",Hwang et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 17,PHI:31,UniProt,P30573,EMBL,BAA02707,,,IFO1060,CHS3,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,chitin synthase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,7479842,PubMed,10.1073/pnas.92.23.10570,,,,Bulawa et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 18,PHI:33,UniProt,P43076,EMBL,AAA68196,,,SC5314,PHR1,,,,,,,5476,Candida albicans,5476,CAF3-1,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,membrane protein; pH responsive protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,7591097,PubMed,no data found,,,,Ghannoum et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 19,PHI:35,UniProt,O13337,EMBL,AAB69694,,,Guy11,CON7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,,MU,,Not in PubMed,10.1094/MPMI-8-0949,Shi et al. (1995) MOLECULAR PLANT-MICROBE INTERACTIONS 8 (6): 949-959,,Sequence of rescued plasmid insertion,Shi and Leung,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 20,PHI:36,UniProt,Q01143,EMBL,AAA93199,,,,CPKA,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,PKA catalytic subunit,"GO:0009405, IMP; GO:0044409, IMP; GO:0044412, IMP",GO,cAMP signalling,loss of pathogenicity,,yes,yes,yes,,wild type,wild type,wild type,wild type,,,,,,,,gene deletion,,,MU,8535140,PubMed,10.1105/tpc.7.11.1869,,,"mutations in CPKA, are specific for pathogenicity, with deletion mutants of cpkA showing impaired appressorial penetration but efficient sporulation and mating",Mitchell and Dean,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 21,PHI:37,UniProt,Q99129,EMBL,AAC37439,,,518,MYP1,,,,,,,5270,Ustilago maydis,237631,518; 521,smut (corn),monocots,4577,Zea mays (related: maize),,,,,mycelial development,"GO:0009405, IMP",GO,,reduced virulence,no,,,,,,,,,,,,,,,,gene deletion,,,TKB,8647387,PubMed,no data found,,,,Giasson and Kronstad,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 22,PHI:38,UniProt,Q02039,EMBL,AAA86496,,,US238.1,NIP1,,,,,,,914237,Rhynchosporium commune,,,scald; leaf blotch,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,other evidence,,,MU,7556057,PubMed,no data found,,,,Rohe et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 23,PHI:39,UniProt,Q6Q475,EMBL,AAS60096,,,,GP42 (PEP13),,,,,,,67593,Phytophthora sojae,,,root rot,eudicots,4043,Petroselinum crispum (related: parsley),,,,,transglutaminase,"GO:0003810, IDA",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,SK,MU; SH,7892267,PubMed,10.1073/pnas.92.6.2338,,,previously known as Phytophthora megasperma f. sp. glycinea,Nurnberger et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 24,PHI:40,UniProt,P79068,EMBL,BAA18956,,,104-T,PKS1,,,,,,,5462,Colletotrichum lagenaria,,104-T,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,polyketide synthase,"GO:0009405, IMP; GO:0044409, IMP; GO:0042438",GO,melanin biosynthesis,reduced virulence,,yes,yes,no,,,,,,,,,,,,,gene complementation,,,MU,7500937,PubMed,no data found,,,pathogen formerly called Colletotrichum lagenarium,Takano et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 25,PHI:41,UniProt,Q01145,EMBL,AAA80239,,,,PWL1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene complementation,,,TKB; MU,8664503,PubMed,no data found,,,,Kang et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 26,PHI:42,UniProt,Q01144,EMBL,AAA91019,,,4392-1-6,PWL2,,,,,,,318829,Magnaporthe oryzae,,4392-1-6,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene complementation,,,MU,7549480,PubMed,10.1105/tpc.7.8.1221,,,Transfer into other strains by crossing,Sweigard et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 27,PHI:44,UniProt,Q8NJV0,EMBL,AAM90953,,,A18,TRI5,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4498,Avena sativa (related: oat),cv. Porter,,,seedling,trichodiene synthase,GO:0045482,GO,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption; gene complementation,,,MU; AB,8589414,PubMed,no data found,,,Tri5- strains inconsistently caused less disease than their wild-type progenitor strain,Proctor et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 28,PHI:44,UniProt,Q8NJV0,EMBL,AAM90953,,,A18,TRI5,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Caldwell,,,seedling,trichodiene synthase,GO:0045482,GO,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption; gene complementation,,,MU; AB,8589414,PubMed,no data found,,,Tri5- strains inconsistently caused less disease than their wild-type progenitor strain,Proctor et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 29,PHI:44,UniProt,Q8NJV0,EMBL,AAM90953,,,A18,TRI5,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Marshall,,,seedling,trichodiene synthase,GO:0045482,GO,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption; gene complementation,,,MU; AB,8589414,PubMed,no data found,,,Tri5- strains inconsistently caused less disease than their wild-type progenitor strain,Proctor et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 30,PHI:44,UniProt,Q8NJV0,EMBL,AAM90953,,,A18,TRI5,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4550,Secale cereale (related: rye),common winter rye,,,seedling,trichodiene synthase,"GO:0009405, IMP; GO:0044412; GO:0045482",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene disruption; gene complementation,,,MU; AB,8589414,PubMed,no data found,,,,Proctor et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 31,PHI:44,UniProt,Q8NJV0,EMBL,AAM90953,,,A18,TRI5,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling,trichodiene synthase,GO:0045482,GO,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption; gene complementation,,,MU; AB,8589414,PubMed,no data found,,,,Proctor et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 32,PHI:44,UniProt,Q8NJV0,EMBL,AAM90953,,,A18,TRI5,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Wheaton,,,seedling,trichodiene synthase,"GO:0009405, IMP; GO:0044412; GO:0045482",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene disruption; gene complementation,,,MU; AB,8589414,PubMed,no data found,,,,Proctor et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 33,PHI:44,UniProt,Q8NJV0,EMBL,AAM90953,,,A18,TRI5,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Wheaton,,,spike,trichodiene synthase,"GO:0009405, IMP; GO:0044412; GO:0045482",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene disruption; gene complementation,,,MU; AB,8589414,PubMed,no data found,,,,Proctor et al.,1995,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 34,PHI:3518,UniProt,Q00909,EMBL,AAM90953,,,A18,TRI5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Landsberg erecta,,,inflorescence,trichodiene synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion; biochemical analysis,,,AB; AC,18179606,PubMed,10.1111/j.1469-8137.2007.02333.x,Cuzick et al. (2008) New Phytologist 177(4): 990-1000,kim.hammond-kosack@bbsrc.ac.uk,,Cuzick et al.,2008,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 35,PHI:3518,UniProt,Q00909,EMBL,AAM90953,,,A18,TRI5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spike,trichodiene synthase,,,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; biochemical analysis,,,AB; AC,18179606,PubMed,10.1111/j.1469-8137.2007.02333.x,Cuzick et al. (2008) New Phytologist 177(4): 990-1000,kim.hammond-kosack@bbsrc.ac.uk,,Cuzick et al.,2008,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 36,PHI:47,UniProt,Q00819,EMBL,AAB06581,,,,CAP64,,,,,,,5207,Cryptococcus neoformans,,B4131,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,capsule formation,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene deletion; gene complementation,,,TKB; KHK,8675296,PubMed,no data found,,,,Chang et al.,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 37,PHI:48,UniProt,Q59J76,EMBL,BAD91825,,,T49,CnLAC1,,,,,,,5207,Cryptococcus neoformans,,B-4476; E2,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,laccase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,8760791,PubMed,10.1084/jem.184.2.377,,,"gene disruption, with complementation and gene disruption, no complementation",Salas et al.,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 38,PHI:48,UniProt,Q59J76,EMBL,BAD91825,,,T49,CnLAC1,,,,,,,5207,Cryptococcus neoformans,,serotype D strain ATCC 208819,cryptococcosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,laccase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,12438649,PubMed,10.1073/pnas.232568599,,,"gene disruption, with complementation and gene disruption, no complementation",,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 39,PHI:48,UniProt,Q59J76,EMBL,BAD91825,,,T49,CnLAC1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,laccase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,15972469,PubMed,10.1128/IAI.73.7.3842-3850.2005,,,Tested in G.mellonella caterpillars in the final instar larval stage,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 40,PHI:49,UniProt,Q00580,EMBL,AAA67706,,,EP155,CPG1,,,,,,,5116,Cryphonectria parasitica,660469,EP155,blight (chestnut),eudicots,134033,Castanea dentata (related: american chestnut),,,,,G alpha protein subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,11038529,PubMed,10.1073/pnas.93.24.14122,,,,Gao and Nuss,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 41,PHI:52,UniProt,Q01168,EMBL,AAB03415,,,GUY11,NUT1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,GATA transcription factor for nitrogen metabolism,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU,8757395,PubMed,no data found,,,partial gene disruption with complementation in A. nidulans,Froeliger and Carpenter,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 42,PHI:52,UniProt,Q01168,EMBL,AAB03415,,,GUY11,NUT1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,global regulation of nitrogen utilisation,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,AS,AB; MU,11277427,PubMed,10.1094/MPMI.2001.14.3.300,,annie.osbourn@bbsrc.ac.uk,Fully pathogenic to leaves but no clear lesions on roots,Dufresne and Osbourn,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 43,PHI:53,UniProt,Q6LD98,EMBL,AAP19639,,,,PDA1,conditionally dispensable (CD) chromosome,,,,,,169388,Fusarium solani,,77-13-7,root rot,eudicots,3888,Pisum sativum (related: pea),,,,,pisatin demethylase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,,MU; KHK,12925899,PubMed,10.1007/s00294-003-0428-x,Wasmann and VanEtten (1996) MOLECULAR PLANT-MICROBE INTERACTIONS 9 (9): 793-803,,"Expression during early infection stage (pisatin), different GC content, on a dispensable chromosome. NCBI species Nectria haematococca merged into Fusarium solani",Wasmann and VanEtten,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 44,PHI:55,UniProt,Q92217,EMBL,AAB08104,,,C4,PKS1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),,,,,polyketide synthase,"GO:0009405, IMP; GO:0044412",GO,T-toxin production,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene disruption,,,MU,8953776,PubMed,10.1105/tpc.8.11.2139,,,Cochliobolus heterostrophus is pathogen anamorph name,Yang et al.,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 45,PHI:56,UniProt,Q92246,EMBL,AAC49521,,,Guy11,PMK1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409, IMP; GO:0044412, IMP; GO:0004707, IMP",GO,,loss of pathogenicity,,yes,yes,yes,,wild type,sterile,,,,,,,,,,gene deletion; gene complementation,,,MU,8946911,PubMed,10.1101/gad.10.21.2696,,,"FUS3/KSS1 homologue; gene deletion, with complementation in S. cerevisiae",Xu and Hamer,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 46,PHI:57,UniProt,Q99101,EMBL,AAC32736,,,FBD11,PRF1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,transcription factor,"GO:0009405, IMP",GO,,loss of pathogenicity,yes,,,,,,,,,,,,,,,,gene disruption,,,MU,8612587,PubMed,no data found,,,,Hartmann et al.,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 47,PHI:58,UniProt,Q00455,EMBL,BAA13009,,,104-T,SCD1,,,,,,,5462,Colletotrichum lagenaria,,9201Y,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,scytalone dehydratase,"GO:0009405, IMP; GO:0044409, IMP; GO:0030411, NAS",GO,melanin biosynthesis,reduced virulence,,yes,yes,,,,,,,,,,,,,,gene deletion; gene complementation,,,MU; KHK,8953707,PubMed,no data found,,,melanin mutant complemented with wild-type gene sequence. pathogen formerly called Colletotrichum lagenarium,Kubo et al.,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 48,PHI:59,UniProt,P87025,EMBL,BAA18962,,,104-T,THR1,,,,,,,5462,Colletotrichum lagenaria,,104-T,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,reductase,"GO:0009405, IMP; GO:0044409",GO,melanin biosynthesis,reduced virulence,,yes,yes,,,,,,,,,,,,,,gene disruption,,,MU; KHK,8672814,PubMed,no data found,,,pathogen formerly called Colletotrichum lagenarium,Perpetua et al.,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 49,PHI:60,UniProt,Q00357,EMBL,AAB36607,,,SB111a,TOXA,,,,,,,5017,Bipolaris zeicola,,,leaf spot,monocots,4577,Zea mays (related: maize),,,,,toxin pump,,,toxin secretion,lethal,,,,,,,,,,,,,,,,,gene disruption,,,MU; JA,8704997,PubMed,10.1099/13500872-142-6-1557,,,pathogen formerly called Cochliobolus carbonum teleomorph name,Pitkin et al.,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 50,PHI:61,UniProt,P43070,EMBL,AAA21151,,,ATCC 10261,BGL2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,"cell wall 1,3-beta-glucosyltransferase (bgl2p)","GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9043114,PubMed,10.1099/00221287-143-2-367,,,,Sarthy et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 51,PHI:62,UniProt,P52498,EMBL,AAB81286,,,B792,caRSR1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,cell morphogenesis,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,reduced,reduced,,,,,,,,gene disruption; gene complementation,,,TKB,9308185,PubMed,10.1099/00221287-143-9-3033,,,,Yaar et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 52,PHI:65,UniProt,O14435,EMBL,AAC49838,,,EP155,CPGB-1,,,,,,,5116,Cryphonectria parasitica,660469,EP155,blight (chestnut),eudicots,134033,Castanea dentata (related: american chestnut),,,,,G beta protein subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced,,,,,,,,,,,gene disruption,,,TKB,9353946,PubMed,10.1094/MPMI.1997.10.8.984,,,,Kasahara et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 53,PHI:66,UniProt,P43078,EMBL,AAC05307,,,,CPP1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,tyrosine phosphatase,"GO:0009405, IMP",GO,VH1 dual specificity protein phosphatase,reduced virulence,,,,,,,,reduced,,,,,,,,,gene disruption; gene complementation,,,TKB,9398674,PubMed,10.1091/mbc.8.12.2539,,,,Csank et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 54,PHI:67,UniProt,P43068,EMBL,CAA54129,,,1001 (ATCC 64385),MKC1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9009353,PubMed,no data found,,,SLT2 homologue,DiezOrejas et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 55,PHI:68,UniProt,P0CY26,EMBL,AAA34368,,,SS,SAP1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,aspartyl proteinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284116,PubMed,no data found,,,,Hube et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 56,PHI:68,UniProt,P0CY26,EMBL,AAA34368,,,SS,SAP1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,,aspartyl proteinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284116,PubMed,no data found,,,,Hube et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 57,PHI:69,UniProt,Q00298,EMBL,CAA93255,,,SAS56,CUTA,,,,,,PHI:541,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Hiltrud,,,,cutinase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,,Not in PubMed,10.1111/J.1364-3703.2004.00280.X,"Reis et al. (2005) MOLECULAR PLANT PATHOLOGY, 6(3) 257-267",,,,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 58,PHI:69,UniProt,Q00298,EMBL,CAA93255,,,SAS56,CUTA,,,,,,PHI:541,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3570,Dianthus caryophyllus (related: clove pink),,,,,cutinase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,,Not in PubMed,10.1111/J.1364-3703.2004.00280.X,"Reis et al. (2005) MOLECULAR PLANT PATHOLOGY, 6(3) 257-267",,,,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 59,PHI:69,UniProt,Q00298,EMBL,CAA93255,,,SAS56,CUTA,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,13546,Gerbera (no common name found),,,,flower,cutinase,,,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption,,,TKB; KHK,9002270,PubMed,10.1094/MPMI.1997.10.1.30,,,,Van Kan et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 60,PHI:69,UniProt,Q00298,EMBL,CAA93255,,,SAS56,CUTA,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,cutinase,,,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption,,,TKB; KHK,9002270,PubMed,10.1094/MPMI.1997.10.1.30,,,,Van Kan et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 61,PHI:69,UniProt,Q00298,EMBL,CAA93255,,,SAS56,CUTA,,,,,,PHI:541,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,13546,Gerbera (no common name found),,,,,cutinase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,20565655,PubMed,10.1111/J.1364-3703.2004.00280.X,"Reis et al. (2005) MOLECULAR PLANT PATHOLOGY, 6(3) 257-267",,,,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 62,PHI:69,UniProt,Q00298,EMBL,CAA93255,,,SAS56,CUTA,,,,,,PHI:541,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Paradiser,,,,cutinase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,,Not in PubMed,10.1111/J.1364-3703.2004.00280.X,"Reis et al. (2005) MOLECULAR PLANT PATHOLOGY, 6(3) 257-267",,,,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 63,PHI:70,UniProt,Q00364,EMBL,CAA78400,,,race 5,ECP1,,,,,,,5499,Fulvia fulva,,race 5,leaf mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,extracellular protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,reduced,,,,,,,,,,gene deletion,,,TKB; KHK,,Not in PubMed,10.1094/MPMI.1997.10.6.725,Lauge et al. (1997) MOLECULAR PLANT MICROBE INTERACTIONS 10 (6): 725-734,,,Laugé et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 64,PHI:71,UniProt,Q00365,EMBL,CAA78401,,,race 5,ECP2,,,,,,,5499,Fulvia fulva,,race 5,leaf mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced,reduced,,,,,,,,,,gene deletion,,,TKB; KHK,,Not in PubMed,10.1094/MPMI.1997.10.6.725,Lauge et al. (1997) MOLECULAR PLANT MICROBE INTERACTIONS 10 (6): 725-734,,,Laugé et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 65,PHI:71,UniProt,Q00365,EMBL,CAA78401,,,race 5,ECP2,,,,,,,5499,Fulvia fulva,,race 5,leaf mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion,,,TKB; KHK,9671796,PubMed,10.1073/pnas.95.15.9014,Proc Natl Acad Sci U S A 1998 Jul 21;95(15):9014-8.,,Virulent on tomato plants possessing the Cf-ECP2 resistance gene,Lauge et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 66,PHI:72,UniProt,P0DJ06,EMBL,AAM21050,,,CAI4,SAP2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,aspartyl proteinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284116,PubMed,no data found,,,,Hube et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 67,PHI:72,UniProt,P0DJ06,EMBL,AAM21050,,,CAI4,SAP2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,,aspartyl proteinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284116,PubMed,no data found,,,,Hube et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 68,PHI:73,UniProt,P0CY28,EMBL,AAA34372,,,SS,SAP3,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,,aspartyl proteinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284116,PubMed,no data found,,,,Hube et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 69,PHI:73,UniProt,P0CY28,EMBL,AAA34372,,,SS,SAP3,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,aspartyl proteinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284116,PubMed,no data found,,,,Hube et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 70,PHI:75,UniProt,P0CN96,EMBL,AAD46575,,,JEC21,GPA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,KHK; MU,15972469,PubMed,10.1128/IAI.73.7.3842-3850.2005,,,Tested in G.mellonella caterpillars in the final instar larval stage,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 71,PHI:75,UniProt,P0CN96,EMBL,AAD46575,,,JEC21,GPA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,G alpha protein subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,KHK; MU,9389652,PubMed,10.1101/gad.11.23.3206,,,,Alspaugh et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 72,PHI:75,UniProt,P0CN96,EMBL,AAD46575,,,JEC21,GPA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,G alpha protein subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,KHK; MU,12438649,PubMed,10.1073/pnas.232568599,,,Tested in C.elegans strain N2 Bristol,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 73,PHI:76,UniProt,P87032,EMBL,AAC49724,,,FB1,GPA1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,G alpha protein subunit,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,MU,9155019,PubMed,10.1093/emboj/16.8.1934,,,,Regenfelder et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 74,PHI:77,UniProt,P87033,EMBL,AAC49725,,,FB1,GPA2,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,G alpha protein subunit,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,MU,9155019,PubMed,10.1093/emboj/16.8.1934,,,,Regenfelder et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 75,PHI:78,UniProt,P87034,EMBL,AAC49726,,,FB1,GPA3,,,,,,,5270,Ustilago maydis,559306,FB1; FB2; CL13; SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,G alpha protein subunit,"GO:0009405, IMP",GO,,loss of pathogenicity,yes,,,,,,,,,,,,,,,,gene disruption,,,MU,9155019,PubMed,10.1093/emboj/16.8.1934,,,,Regenfelder et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 76,PHI:79,UniProt,P87035,EMBL,AAC49727,,,FB1,GPA4,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,G alpha protein subunit,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,MU,9155019,PubMed,10.1093/emboj/16.8.1934,,,,Regenfelder et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 77,PHI:80,UniProt,Q00313,EMBL,AAB39507,,,,TOP1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,topoisomerase I,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9043115,PubMed,10.1099/00221287-143-2-377,,,,Jiang et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 78,PHI:81,UniProt,O13328,EMBL,AAB66482,,,70-15,MAC1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,adenylate cyclase,"GO:0009405, IMP",GO,cAMP signalling,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,MU,9401122,PubMed,10.1105/tpc.9.11.1973,,,Pleiotropic effects of mutant allele; Partial gene deletion,Choi and Dean,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 79,PHI:82,UniProt,O13314,EMBL,AAB65425,,,70-15,MAGA,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,G alpha protein subunit,,,,unaffected pathogenicity,,no,no,no,,wild type,no mature asci,wild type,,,,,,,,,gene deletion,,,MU,9390422,PubMed,10.1094/MPMI.1997.10.9.1075,,,Partial gene deletion,Liu and Dean,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 80,PHI:83,UniProt,O13315,EMBL,AAB65426,,,70-15,MAGB,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,G alpha protein subunit,"GO:0009405, IMP; GO:0044409, IMP; GO:0030437, IMP",GO,cAMP signalling,reduced virulence,,yes,yes,,,reduced,no perithecia formation,reduced,,,,,,,,,gene disruption; gene complementation,,,MU,9390422,PubMed,10.1094/MPMI.1997.10.9.1075,,,,Liu and Dean,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 81,PHI:84,UniProt,O13316,EMBL,AAB65427,,,70-15,MAGC,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,G alpha protein subunit,"GO:0030437, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,MU,14667055,PubMed,no data found,,,Partial gene deletion,Liu and Dean,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 82,PHI:85,UniProt,O14427,EMBL,AAB68613,,,,CLA4,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,MU,9259554,PubMed,no data found,,,,Leberer et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 83,PHI:86,UniProt,P43079,EMBL,AAA64692,,,,CPH1,,,,,,PHI:87,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,regulatory protein,"GO:0009405, IGI; GO:0044412",GO,,loss of pathogenicity,,,,yes,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9298905,PubMed,10.1016/s0092-8674(00)80358-x,,,,Lo et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 84,PHI:87,UniProt,P43064,EMBL,CAA83640,,,ATCC10231,EFG1,,,,,,PHI:86,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IGI",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9298905,PubMed,10.1016/s0092-8674(00)80358-x,,,,Lo et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 85,PHI:87,UniProt,P43064,EMBL,CAA83640,,,ATCC10231,EFG1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,Ras-protein kinase A,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15760450,PubMed,10.1111/j.1462-5822.2004.00476.x,,,,Park et al.,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 86,PHI:88,UniProt,P41749,EMBL,AAA85279,,,70,PECA,,,,,,,5059,Aspergillus flavus,5059,12,,eudicots,3635,Gossypium hirsutum (related: cotton),,,,,polygalacturonase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,9293005,PubMed,10113/23538,,,,Shieh et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 87,PHI:89,UniProt,O42773,EMBL,AAB97372,,,H99,CNA1,,,,,,,5207,Cryptococcus neoformans,,serotype A strain M049,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,calcineurin A catalytic subunit/ serine/threonine phosphatase 2B,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU; KHK,9184205,PubMed,10.1093/emboj/16.10.2576,,,,Odom et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 88,PHI:95,UniProt,P53707,EMBL,AAB66368,,,ATCC 26555,CSP37,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,membrane protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9244249,PubMed,10.1128/jb.179.15.4654-4663.1997,,,,Sentandreu et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 89,PHI:96,UniProt,P43098,EMBL,AAA34345,,,4918,FAS2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,fatty acid synthetase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9009352,PubMed,no data found,,,,Zhao et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 90,PHI:96,UniProt,P43098,EMBL,AAA34345,,,4918,FAS2,,,,,,,5476,Candida albicans,,,candidiasis,rodents,10114,Rattus (related: rat),,,,,fatty acid synthetase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,8828218,PubMed,10.1099/00221287-142-9-2509,,,Oropharyngeal candidiasis,Zhao et al.,1996,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 91,PHI:97,UniProt,Q92215,EMBL,AAC62818,,,SB111,TOXC,,,,,,,5017,Bipolaris zeicola,,164R10,leaf spot,monocots,4577,Zea mays (related: maize),,,,,fatty acid synthetase,"GO:0009405, IMP; GO:0044412",GO,HC-toxin biosynthesis,reduced virulence,,no,no,yes,,,,wild type,wild type,,,,,,,,gene disruption,,,TKB; JA,9057326,PubMed,10.1094/MPMI.1997.10.2.207,,,pathogen formerly called Cochliobolus carbonum teleomorph name,Ahn and Walton,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 92,PHI:98,UniProt,O13394,EMBL,AAB84284,,,518,umCHS5,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,chitin synthase,"GO:0009405, IMP",GO,,reduced virulence,no,,,,,,,reduced,,,,,,,,,gene deletion; gene complementation,,,TKB,9454647,PubMed,10.1006/fgbi.1997.1014,,,,Xoconostle-Cazares et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 93,PHI:99,UniProt,Q8J0D1,EMBL,BAC41196,,,Guy11,ACR1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,putative transcription factor,"GO:0009405, IMP; GO:0044409, IMP",GO,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,MU,9742203,PubMed,10.1006/fgbi.1998.1053,,,Plasmid insertion,Lau and Hamer,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 94,PHI:100,UniProt,Q99079,EMBL,AAA75366,,,strain 518 (a2b2),ADR1,,,,,,,5270,Ustilago maydis,237631,d132; 518; 521,smut (corn),monocots,4577,Zea mays (related: maize),,,,,PKA catalytic subunit,"GO:0009405, IMP; GO:0051701",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,MU,9576944,PubMed,10.1073/pnas.95.10.5684,,,,Durrenberger et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 95,PHI:101,UniProt,O59897,EMBL,AAC39471,,,B-5233,ALB1,,,,,,,746128,Aspergillus fumigatus,,B-5233,respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,,polyketide synthase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9620950,PubMed,no data found,,,,Tsai et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 96,PHI:103,UniProt,O94100,EMBL,AAC64374,,,SAS56,BCPGA1,,,,,,,40559,Botrytis cinerea,40559,SAS56,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,endopolygalacturonase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene disruption,,,MU,9768518,PubMed,10.1094/MPMI.1998.11.10.1009,,,Tested on tomato leaves,ten Have et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 97,PHI:103,UniProt,O94100,EMBL,AAC64374,,,SAS56,BCPGA1,,,,,,,40559,Botrytis cinerea,40559,SAS56,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,endopolygalacturonase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene disruption,,,MU,9768518,PubMed,10.1094/MPMI.1998.11.10.1009,,,Tested on tomato fruits,ten Have et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 98,PHI:103,UniProt,O94100,EMBL,AAC64374,,,SAS56,BCPGA1,,,,,,,40559,Botrytis cinerea,40559,SAS56,grey mold,eudicots,3750,Malus domestica (related: apple),,,,,endopolygalacturonase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene disruption,,,MU,9768518,PubMed,10.1094/MPMI.1998.11.10.1009,,,Tested on apple fruits,ten Have et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 99,PHI:104,UniProt,Q00310,EMBL,CAA67930,,,CAI-4,CaMNT1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,,synthesis of mannoproteins,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9636208,PubMed,10.1073/pnas.95.13.7670,,,,Buurman et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 100,PHI:104,UniProt,Q00310,EMBL,CAA67930,,,CAI-4,CaMNT1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,synthesis of mannoproteins,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9636208,PubMed,10.1073/pnas.95.13.7670,,,,Buurman et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 101,PHI:105,UniProt,Q9UWF6,EMBL,AAC61890,,,SC5314,PLB1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,phospholipase B,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9748287,PubMed,10.1074/jbc.273.40.26078,,,,Leidich et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 102,PHI:106,UniProt,O13289,EMBL,AAC39448,,,ATCC 10261,CAT1,,,,,,,5476,Candida albicans,5476,ATCC 10261,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,catalase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9573075,PubMed,no data found,,,,Wysong et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 103,PHI:107,UniProt,Q5A1D3,EMBL,EAK96519,,,SC5314,CEK1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9596738,PubMed,no data found,,,FUS3/KSS1 homologue,Csank et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 104,PHI:109,UniProt,P87248,EMBL,AAB61403,,,UPS9,CLK1,,,,,,,290576,Colletotrichum lindemuthianum,290576,UPS9,anthracnose,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,protein kinase (ser/thr),"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,reduced virulence,,no,yes,yes,,,,,,,,,,,,,gene deletion,,,MU; JK,9450334,PubMed,10.1094/MPMI.1998.11.2.99,,,Partial gene deletion,Dufresne et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 105,PHI:111,UniProt,Q01905,EMBL,AAB49807,,,88069,INF1,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight,eudicots,4113,Solanum tuberosum (related: potato),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene disruption,,,MU,9724689,PubMed,10.1105/tpc.10.9.1413,,,,Kamoun et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 106,PHI:112,UniProt,Q01446,EMBL,AAC49410,,,156-30-6,MAK1,,,,,,,169388,Fusarium solani,,230-30-6,root rot,eudicots,3827,Cicer arietinum (related: chickpea),,,,,maackiain detoxification,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,,Not in PubMed,10.1094/MPMI.1998.11.4.317,Enkerli et al. (1998) MOLECULAR PLANT-MICROBE INTERACTIONS 11 (4): 317-326,,NCBI species Nectria haematococca merged into Fusarium solani,Enkerli et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 107,PHI:113,UniProt,O13352,EMBL,AAC63682,,,Guy11,MPS1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409",GO,osmotic sensing,loss of pathogenicity,,no,yes,no,,reduced,,,,,,,,,,,gene deletion; gene complementation,,,MU,9770551,PubMed,10.1073/pnas.95.21.12713,,,SLT2 homologue; Cloning by PCR,Xu et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 108,PHI:114,UniProt,O00094,EMBL,AAC05015,,,42-87,PG1,,,,,,,5507,Fusarium oxysporum,,race 2 strain 42-87,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,endopolygalacturonase,,,,unaffected pathogenicity,,,,,,,,,,,pectin and galacturonic acid,,,,,,gene complementation,,,MU; AB,9450333,PubMed,10.1094/MPMI.1998.11.2.91,,,Expression during all infection stages; Gene introduction to naturally deficient strains,Di Pietro et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 109,PHI:115,UniProt,Q00359,EMBL,AAC26146,,,SB111,PGX1,,,,,,,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,exopolygalacturonase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,MU; JA,9546185,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,Scott-Craig et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 110,PHI:116,UniProt,O60026,EMBL,CAA76740,,,ATCC46645,PKSP,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,,polyketide synthase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9832321,PubMed,no data found,,,,Langfelder et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 111,PHI:120,UniProt,O42620,EMBL,AAB88887,,,4091-5-8; 4091-5-8,PTH2,,,,,,,318829,Magnaporthe oryzae,1274781,4091-5-8; CP987,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,carnitine acetyl transferase,"GO:0009405, IMP",GO,fatty acid oxidation,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU,9574508,PubMed,10.1094/MPMI.1998.11.5.404,,,Identification by REMI,Sweigard et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 112,PHI:121,UniProt,O42621,EMBL,AAB88888,,,4091-5-8,PTH3,,,,,,,318829,Magnaporthe oryzae,1274781,4091-5-8; CP987,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,imidazole glycerol phosphate dehydrogenase,"GO:0009405, IMP",GO,histidine biosynthesis,loss of pathogenicity,,,,,,wild type,wild type,wild type,wild type,,,,,,,,gene disruption; gene complementation,,,MU,9574508,PubMed,10.1094/MPMI.1998.11.5.404,,,Identification by REMI,Sweigard et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 113,PHI:122,UniProt,O42624,EMBL,AAB88886,,,,PTH8,,,,,,,318829,Magnaporthe oryzae,,9041-5-8,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,pathogenicity protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU,9574508,PubMed,10.1094/MPMI.1998.11.5.404,,,Identification by REMI,Sweigard et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 114,PHI:123,UniProt,O42622,EMBL,AAB88889,,,4091-5-8,PTH9 (NTH1),,,,,,,318829,Magnaporthe oryzae,,9041-5-8,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,trehalase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,reduced,,,,,,,,,,,gene disruption; gene complementation,,,MU,9574508,PubMed,10.1094/MPMI.1998.11.5.404,,,Identification by REMI,Sweigard et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 115,PHI:124,UniProt,P53705,EMBL,AAA96019,,,10261,INT1,,,,,,,5476,Candida albicans,5476,ATCC 10261,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,integrin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9478896,PubMed,10.1126/science.279.5355.1355,,,,Gale et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 116,PHI:125,UniProt,P43093,EMBL,AAA17877,,,WO1,SAP4,,,,,,PHI:126; PHI:127,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,,aspartyl proteinase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284117,PubMed,no data found,,,,Sanglard et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 117,PHI:125,UniProt,P43093,EMBL,AAA17877,,,WO1,SAP4,,,,,,PHI:126; PHI:127,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,aspartyl proteinase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284117,PubMed,no data found,,,,Sanglard et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 118,PHI:126,UniProt,P43094,EMBL,CAA82923,,,Ca74,SAP5,,,,,,PHI:125; PHI:127,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,,aspartyl proteinase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284117,PubMed,no data found,,,,Sanglard et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 119,PHI:126,UniProt,P43094,EMBL,CAA82923,,,Ca74,SAP5,,,,,,PHI:125; PHI:127,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,aspartyl proteinase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284117,PubMed,no data found,,,,Sanglard et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 120,PHI:127,UniProt,P43095,EMBL,CAA82924,,,Ca74,SAP6,,,,,,PHI:125; PHI:126,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,aspartyl proteinase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284117,PubMed,no data found,,,,Sanglard et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 121,PHI:127,UniProt,P43095,EMBL,CAA82924,,,Ca74,SAP6,,,,,,PHI:125; PHI:126,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,,aspartyl proteinase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9284117,PubMed,no data found,,,,Sanglard et al.,1997,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 122,PHI:128,UniProt,O14448,EMBL,AAC34140,,,Guy11,SUM1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,PKA regulatory subunit,,,cAMP signalling,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene mutation: characterised,,,MU,9707535,PubMed,10.1105/tpc.10.8.1361,,,Point mutation,Adachii and Hamer,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 123,PHI:129,UniProt,O59900,EMBL,AAC39450,,,B-4500,CAP60,,,,,,,5207,Cryptococcus neoformans,,B-4500,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,capsule associated protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; SH,9573112,PubMed,no data found,,,,Chang and Kwon-Chung,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 124,PHI:130,UniProt,Q92410,EMBL,CAA69223,,,,TPS1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,trehalose-6-phosphate synthase,"GO:0009405, IMP; GO:0003825, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9683476,PubMed,no data found,,,,Zaragoza et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 125,PHI:131,UniProt,O93842,EMBL,AAD12756,,,NRRL 3299,TRI12,,,,,,,5514,Fusarium sporotrichioides,5514,NRRL 3299,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,toxin efflux pump,,,trichothecene secretion,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,MU; AB,10485289,PubMed,no data found,,,,Alexander et al.,1998,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 126,PHI:132,UniProt,O13407,EMBL,AAB86640,,,Guy11,ABC1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,ABC transporter,"GO:0042626; GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,wild type,,,,,,,,,,,gene deletion,,,MU,9927411,PubMed,10.1093/emboj/18.3.512,,,Partial gene deletion,Urban et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 127,PHI:133,UniProt,O93800,EMBL,BAA36588,,,15A,AKT1,,,,,,,5599,Alternaria alternata,5599,15A,black spot,eudicots,23211,Pyrus communis (related: pear),,,,,"carboxyl-activating enzyme, essential for AK toxin","GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,no,yes,yes,,,,,,,,,,,,,gene disruption,,,TKB,10432635,PubMed,10.1094/MPMI.1999.12.8.691,,,,Tanaka et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 128,PHI:134,UniProt,O93801,EMBL,BAA36589,,,15A,AKT2,,,,,,,5599,Alternaria alternata,5599,15A,black spot,eudicots,23211,Pyrus communis (related: pear),,,,,"unknown, mutant is AK toxin non-producer","GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,no,yes,yes,,,,,,,,,,,,,gene disruption,,,TKB,10432635,PubMed,10.1094/MPMI.1999.12.8.691,,,,Tanaka et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 129,PHI:135,UniProt,A4D962,EMBL,AAA91036,,,ATCC 26199,BAD1 (WI-1),,,,,,,5039,Blastomyces dermatitidis,5039,SCB-2; A,,rodents,10090,Mus musculus (related: house mouse),,,,,adhesin,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,10209038,PubMed,10.1084/jem.189.8.1207,,,,Brandhorst et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 130,PHI:136,UniProt,Q5AHA0,EMBL,AAC39451,,,SC5314,CaHK1 (CHK1),,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,histidine kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10417206,PubMed,no data found,,,Heterozygous disruption,Calera et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 131,PHI:136,UniProt,Q5AHA0,EMBL,AAC39451,,,SC5314,CaHK1 (CHK1),,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,histidine kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,10572127,PubMed,no data found,,,,Yamada-Okabe et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 132,PHI:136,UniProt,Q5AHA0,EMBL,AAC39451,,,SC5314,CaHK1 (CHK1),,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,histidine kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10417206,PubMed,no data found,,,Homozygous disruption,Calera et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 133,PHI:136,UniProt,Q5AHA0,EMBL,AAC39451,,,SC5314,CaHK1 (CHK1),,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10114,Rattus (related: rat),,,,,histidine kinase,"GO:0009405, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10417206,PubMed,no data found,,,,Calera et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 134,PHI:138,UniProt,O42696,EMBL,BAA24952,,,,CaNIK1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,histidine kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,10572127,PubMed,no data found,,,,Yamada-Okabe et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 135,PHI:139,UniProt,Q7ZA26,EMBL,BAC76819,,,CBS131,CAP10,,,,,,,5207,Cryptococcus neoformans,,cap10F2FO,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,capsule formation,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,10482503,PubMed,no data found,,,,Chang and Kwon-Chung,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 136,PHI:140,UniProt,O42695,EMBL,BAA24951,,,,CaSLN1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,histidine kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,10572127,PubMed,no data found,,,,Yamada-Okabe et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 137,PHI:141,UniProt,O93886,EMBL,AAC78076,,,PR,CFP,,,,,,,84275,Cercospora kikuchii,84275,PR,leaf blight; purple seed stain,eudicots,3847,Glycine max (related: soybean),,,,,cercosporin secretion,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU,10517030,PubMed,10.1094/MPMI.1999.12.10.901,,,,Callahan et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 138,PHI:142,UniProt,Q9UVN7,EMBL,AAF05913,,,C4,CHK1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,no,no,,,absent (no conidia),sterile,reduced,,,,,,,,,gene disruption,,,MU,10557357,PubMed,10.1073/pnas.96.23.13542,,,FUS3/KSS1 homologue. Cochliobolus heterostrophus is pathogen anamorph name,Lev et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 139,PHI:143,UniProt,P32964,EMBL,AAA33353,,,T-442,CHT,,,,,,,1682391,Microdochium sorghi,5563,T-442,leaf spot; leaf blight,monocots,4558,Sorghum bicolor (related: sorghum),,,,,cyanide hydratase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,MU,10587474,PubMed,10.1006/fgbi.1999.1167,,,Expression during infection stage (HCN) NCBI species Gloeocercospora sorghi merged into Microdochium sorghi.,Wang et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 140,PHI:144,UniProt,O59928,EMBL,AAC05829,,,,CHT42,,,,,,,29875,Trichoderma virens,29875,Tv10.4,mycopathogen,basidiomycetes,456999,Rhizoctonia solani (no common name found),,,,,chitinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; altered gene expression / gene regulation: overexpression,,,TKB,10022948,PubMed,no data found,,,,Baek et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 141,PHI:146,UniProt,O42793,EMBL,AAC04355,,,,CT-PKAC,,,,,,,5466,Colletotrichum trifolii,,,anthracnose,eudicots,3879,Medicago sativa (related: alfalfa),,,,,PKA catalytic subunit,"GO:0009405, IMP; GO:0044409",GO,cAMP signalling,loss of pathogenicity,,no,yes,no,,aberrant (altered production of conidia),,,,,,,,,,,gene deletion,,,MU,10226376,PubMed,10.1094/MPMI.1999.12.5.430,,,,Yang and Dickmann,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 142,PHI:149,UniProt,Q92207,EMBL,CAA62214,,,1001,HOG1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10322006,PubMed,no data found,,,HOG1 homologue,Alonso-Monge et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 143,PHI:151,UniProt,Q9UQY5,EMBL,AAF15528,,,a2b3,KPP2,,,,,,,5270,Ustilago maydis,559306,FB1; FB2; CL13,smut (corn),monocots,4577,Zea mays (related: maize),,,,,MAP kinase,"GO:0009405, IMP; GO:0051701; GO:0005186, IMP",GO,,reduced virulence,yes,yes,,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU,10594825,PubMed,no data found,,,FUS3/KSS1 homologue,Muller at al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 144,PHI:153,UniProt,Q9UV51,EMBL,AAF09475,,,Guy11,OSM1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,MAP kinase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,MU,10521531,PubMed,10.1105/tpc.11.10.2045,,,HOG1 homologue,Dixon et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 145,PHI:156,UniProt,Q9Y8E5,EMBL,AAD44111,,,H99,STE12alpha,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,10581270,PubMed,no data found,,,Serotype A,Yue et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 146,PHI:156,UniProt,Q9Y8E5,EMBL,AAD44111,,,H99,STE12alpha,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,10581270,PubMed,no data found,,,Serotype A,Yue et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 147,PHI:157,UniProt,Q9Y885,EMBL,AAD45321,,,SB111,TOXF,,,,,,,5017,Bipolaris zeicola,,164R10,leaf spot,monocots,4577,Zea mays (related: maize),,,,,branched-chain-amino-acid aminotransferase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,MU; JA,10627051,PubMed,10.1099/00221287-145-12-3539,,,pathogen formerly called Cochliobolus carbonum teleomorph name,Cheng et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 148,PHI:158,UniProt,O59918,EMBL,AAC09291,,,521,UKC1,,,,,,,5270,Ustilago maydis,,d132; UT0305; ISO1-1,smut (corn),monocots,4577,Zea mays (related: maize),,,,,protein kinase,"GO:0009405, IMP; GO:0044409",GO,,reduced virulence,no,yes,yes,,,,,,,,,,,,,,gene deletion,,,MU,10102363,PubMed,no data found,,,,Durrenberger and Kronstad,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 149,PHI:159,UniProt,O74686,EMBL,AAC62627,,,G184AS,URA5,,,,,,,5037,Histoplasma capsulatum,5037,G184AS,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),,,,,pyrimidine biosynthesis,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,9916068,PubMed,no data found,,,,Retallack et al.,1999,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 150,PHI:160,UniProt,Q9UVN5,EMBL,AAF01762,,,M-71,AMT,,,,,,,5599,Alternaria alternata,5599,M-71,Alternaria leaf blotch,eudicots,3750,Malus domestica (related: apple),,,,,AM toxin synthase,"GO:0009405, IMP; GO:0044409",GO,toxin synthesis,loss of pathogenicity,,,yes,,,,,,,,,,,,,,gene disruption,,,MU,10875335,PubMed,10.1094/MPMI.2000.13.7.742,,,,Johnson et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 151,PHI:161,UniProt,Q9HG08,EMBL,AAG23132,,,BC29; BC29,BMP1,,,,,,,40559,Botrytis cinerea,40559,A-1-3,grey mold,eudicots,3570,Dianthus caryophyllus (related: clove pink),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,yes,yes,yes,,wild type,,,,,,,,,,,gene deletion; gene complementation,,,MU,10875333,PubMed,10.1094/MPMI.2000.13.7.724,,,"FUS3/KSS1 homologue, Carnation flowers",Zheng et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 152,PHI:161,UniProt,Q9HG08,EMBL,AAG23132,,,BC29; BC29,BMP1,,,,,,,40559,Botrytis cinerea,40559,A-1-3,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,yes,yes,yes,,wild type,,,,,,,,,,,gene deletion; gene complementation,,,MU,10875333,PubMed,10.1094/MPMI.2000.13.7.724,,,"FUS3/KSS1 homologue, Tomato leaves",Zheng et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 153,PHI:161,UniProt,Q9HG08,EMBL,AAG23132,,,BC29; BC29,BMP1,,,,,,,40559,Botrytis cinerea,40559,A-1-3,grey mold,eudicots,3764,Rosa (no common name found),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,yes,yes,yes,,wild type,,,,,,,,,,,gene deletion; gene complementation,,,MU,10875333,PubMed,10.1094/MPMI.2000.13.7.724,,,"FUS3/KSS1 homologue, Rose flowers",Zheng et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 154,PHI:162,UniProt,Q9P8U9,EMBL,AAF69680,,,ATCC 10259,CaFTR1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,high-affinity iron permease,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10807578,PubMed,10.1126/science.288.5468.1062,,,,Ramanan et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 155,PHI:163,UniProt,O42720,EMBL,AAC39354,,,G186AR,CBP1,,,,,,,5037,Histoplasma capsulatum,5037,G186AR ura5; G217B ura5,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),,,,,calcium binding protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU,11082066,PubMed,10.1126/science.290.5495.1368,,,,Sebghati et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 156,PHI:164,UniProt,O43115,EMBL,AAB92221,,,UQ62,CgDN3,,,,,,,474922,Colletotrichum gloeosporioides,,UQ62,anthracnose,eudicots,35627,Stylosanthes (no common name found),,,,,suppressor of plant defense,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,,,reduced rate of appressoria formation,,,early infection stage,,,,,,gene deletion,,,MU; JK,10975650,PubMed,10.1094/MPMI.2000.13.9.929,,,necessarry to avert hypersensitive response in host; Partial gene deletion. Reduced rate of appressoria formation in vitro,Stephenson et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 157,PHI:165,UniProt,Q9UQZ1,EMBL,AAD55385,,,,CgMEK1 (EMK1),,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose,flowering plants,3435,Persea americana (related: avocado),,,,,MAP kinase kinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene disruption,,,MU; JK,10948253,PubMed,10.1105/tpc.12.8.1331,,,STE7 homologue. Tested on Avocado fruits.,Kim et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 158,PHI:166,UniProt,Q9UUS7,EMBL,AAD53262,,,,CHIP2,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose,flowering plants,3435,Persea americana (related: avocado),,,,,unknown,,,,unaffected pathogenicity,,no,no,no,,,,,,,host surface (hard surface contact and ethylene),,,,,,gene deletion,,,MU; JK,10940006,PubMed,10.1128/jb.182.17.4688-4695.2000,,,Tested on Avocado fruits; Partial gene deletion,Kim et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 159,PHI:166,UniProt,Q9UUS7,EMBL,AAD53262,,,,CHIP2,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,unknown,,,,unaffected pathogenicity,,no,no,no,,,,,,,host surface (hard surface contact and ethylene),,,,,,gene deletion,,,MU; JK,10940006,PubMed,10.1128/jb.182.17.4688-4695.2000,,,Partial gene deletion,Kim et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 160,PHI:167,UniProt,Q9UUS8,EMBL,AAF00024,,,,CHIP3,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose,flowering plants,3435,Persea americana (related: avocado),,,,,unknown,,,,unaffected pathogenicity,,no,no,no,,,,,,,host surface (hard surface contact and ethylene),,,,,,gene disruption,,,MU; JK,10940006,PubMed,10.1128/jb.182.17.4688-4695.2000,,,Tested on Avocado fruits.,Kim et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 161,PHI:167,UniProt,Q9UUS8,EMBL,AAF00024,,,,CHIP3,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,unknown,,,,unaffected pathogenicity,,no,no,no,,,,,,,host surface (hard surface contact and ethylene),,,,,,gene disruption,,,MU; JK,10940006,PubMed,10.1128/jb.182.17.4688-4695.2000,,,,Kim et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 162,PHI:169,UniProt,Q9HG15,EMBL,AAG25917,,,UPS9,CLTA1,,,,,,,290576,Colletotrichum lindemuthianum,290576,UPS9,anthracnose,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,transcription factor,"GO:0009405, IMP; GO:0044412",GO,,loss of pathogenicity,,no,no,yes,,,,,,,,,,,,,gene deletion,,,TKB; JK,11006333,PubMed,10.1105/tpc.12.9.1579,,,Partial gene deletion,Dufresne et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 163,PHI:170,UniProt,Q9UW09,EMBL,AAD50496,,,104-T,CMK1,,,,,,,5462,Colletotrichum lagenaria,,104-T,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409, IMP; GO:0044412, IMP; GO:0009847, IMP",GO,,loss of pathogenicity,,yes,yes,yes,,reduced,sterile,wild type,,,,,,,,,gene deletion; gene complementation,,,MU,10755300,PubMed,10.1094/MPMI.2000.13.4.374,,,"FUS3/KSS1 homologue, Partial gene deletion, with complementation in M.grisea. pathogen formerly called Colletotrichum lagenarium",Takano et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 164,PHI:172,UniProt,Q9Y7W4,EMBL,AAD25159,,,,CRK1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,Cdc2-related protein kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11073971,PubMed,10.1128/mcb.20.23.8696-8708.2000,,,,Chen et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 165,PHI:173,UniProt,O42784,EMBL,AAC03782,,,race 1,CTG1,,,,,,,5466,Colletotrichum trifolii,5466,race 1,anthracnose,eudicots,3879,Medicago sativa (related: alfalfa),,,,,G alpha protein subunit,"GO:0009405, IMP; GO:0009847, IMP",GO,,loss of pathogenicity,,yes,,,,,,,unable to germinate conidia,,,,,,,,gene disruption,,,TKB,,Not in PubMed,10.1006/pmpp.2000.0256,Truesdell et al. (2000) PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY 56 (3): 131-140,,,Truesdell et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 166,PHI:174,UniProt,O93806,EMBL,BAA36496,,,,GNA1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,glucosamine-6-phosphate acetyltransferase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10878139,PubMed,10.1099/00221287-146-7-1753,,,,Mio et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 167,PHI:175,UniProt,P46593,EMBL,AAC96368,,,SC5314,HWP1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,surface protein; hyphal development,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10722594,PubMed,10.1128/iai.68.4.1997-2002.2000,,,"A study by Sharkey et al. (Microbiology, 151: 1061-1071) suggests that HWP1 is not in fact a virulence factor",Tsuchimori et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 168,PHI:176,UniProt,Q9UV32,EMBL,AAF24760,,,FBD11,MIG1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,unknown,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,MU,10594035,PubMed,10.1128/mcb.20.1.329-339.2000,,,Expression during biotrophic growth,Basse et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 169,PHI:177,UniProt,Q9UVG2,EMBL,CAB56523,,,LAW 95,ODC,,,,,,,13684,Parastagonospora nodorum,,BS171,glume blotch,monocots,4564,Triticum (related: wheat),,,,,ornithine decarboxylase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,RO,TKB; AC,10799502,PubMed,10.1074/jbc.275.19.14242,Bailey et. (2000) J Biol Chem. 275(19):14242-14247,,complementation in A. nidulans,Bailey et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 170,PHI:178,UniProt,Q9Y7F1,EMBL,AAD31929,,,H237,pabaA,,,,,,,746128,Aspergillus fumigatus,,237,respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,,para-aminobenzoic acid synthetase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,10931287,PubMed,no data found,,,,Brown et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 171,PHI:179,UniProt,Q04701,EMBL,AAA33338,,,T8,PELA,,,,,,PHI:180,169388,Fusarium solani,,T8,root rot,eudicots,3888,Pisum sativum (related: pea),,,,,pectate lyase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10931947,PubMed,10.1073/pnas.160271497,,,NCBI species Nectria haematococca merged into Fusarium solani,Rogers et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 172,PHI:180,UniProt,Q00845,EMBL,AAC49420,,,T8,PELD,,,,,,PHI:179,169388,Fusarium solani,,T8,root rot,eudicots,3888,Pisum sativum (related: pea),,,,,pectate lyase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10931947,PubMed,10.1073/pnas.160271497,,,NCBI species Nectria haematococca merged into Fusarium solani,Rogers et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 173,PHI:181,UniProt,Q96VZ3,EMBL,AAK81847,,,r6,PGX1,,,,,,,5507,Fusarium oxysporum,,race 2 strain 42-87,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,exopolygalacturonase,,,,unaffected pathogenicity,,,,,,,,,,,pectin and PGA,,,,,,gene deletion,,,MU; AB,10755298,PubMed,10.1094/MPMI.2000.13.4.359,,,Expression during all infection stages,Garcia-Maceira et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 174,PHI:182,UniProt,Q9UVQ4,EMBL,AAD55937,,,H99,RAS1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,15075271,PubMed,10.1128/EC.3.2.413-419.2004,,,Tested in Oregon-R flies,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 175,PHI:182,UniProt,Q9UVQ4,EMBL,AAD55937,,,H99,RAS1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,signalling cascade,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,10792722,PubMed,no data found,,,Serotype A,Alspaugh et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 176,PHI:182,UniProt,Q9UVQ4,EMBL,AAD55937,,,H99,RAS1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,signalling cascade,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; SH,12438649,PubMed,10.1073/pnas.232568599,,,Serotype A; Tested in C.elegans strain N2 Bristol,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 177,PHI:182,UniProt,Q9UVQ4,EMBL,AAD55937,,,H99,RAS1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,15972469,PubMed,10.1128/IAI.73.7.3842-3850.2005,,,Tested in G.mellonella caterpillars in the final instar larval stage,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 178,PHI:183,UniProt,Q9HFZ4,EMBL,AAG09787,,,,RBT1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GPI-modified cell wall protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10978273,PubMed,no data found,,,,Braun et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 179,PHI:183,UniProt,Q9HFZ4,EMBL,AAG09787,,,,RBT1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,GPI-modified cell wall protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10978273,PubMed,no data found,,,,Braun et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 180,PHI:184,UniProt,Q9HFZ2,EMBL,AAG09789,,,,RBT4,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,plant-pathogenesis related protein (PR-1),"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,10978273,PubMed,no data found,,,,Braun et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 181,PHI:184,UniProt,Q9HFZ2,EMBL,AAG09789,,,,RBT4,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,plant-pathogenesis related protein (PR-1),"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,10978273,PubMed,no data found,,,,Braun et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 182,PHI:185,UniProt,Q9UW14,EMBL,AAD51714,,,CAI4,RIM101,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,10992507,PubMed,10.1128/iai.68.10.5953-5959.2000,,,,Davis et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 183,PHI:186,UniProt,Q9UW13,EMBL,AAD51715,,,CAI4,RIM8,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,activates RIM101,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10992507,PubMed,10.1128/iai.68.10.5953-5959.2000,,,,Davis et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 184,PHI:187,UniProt,Q9HFW4,EMBL,AAG02418,,,,RUM1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,transcription regulator,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU,11029697,PubMed,no data found,,,,Quadbeck-Seeger et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 185,PHI:188,UniProt,Q9Y880,EMBL,AAD43341,,,SB111,SNF1,,,,,,,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,protein kinase,"GO:0009405, IMP; GO:0044409",GO,,reduced virulence,,no,yes,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU; JA,10662860,PubMed,10.1105/tpc.12.2.237,,,pathogen formerly called Cochliobolus carbonum teleomorph name,Tonukari et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 186,PHI:189,UniProt,Q5AKU6,EMBL,AAD55813,,,SC5314,SSK1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,two component response regulator,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,reduced,,,,,,,,,gene disruption; gene complementation,,,TKB,10639412,PubMed,10.1128/iai.68.2.518-525.2000,,,,Calera et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 187,PHI:190,UniProt,Q5ANJ4,EMBL,EAL04411,,,SC5314,TEC1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,TEA/ATTS transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11069668,PubMed,no data found,,,,Schweizer et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 188,PHI:191,UniProt,Q99324,EMBL,AAB08446,,,353.49,TOM1,,,,,,,39703,Septoria lycopersici,39703,NEV,leaf spot,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,tomatinase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,MU,11106022,PubMed,10.1094/MPMI.2000.13.12.1301,,,Expression during advanced infection stage,Martin-Hernandez et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 189,PHI:194,UniProt,O13465,EMBL,AAC62257,,,H99,URE1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,urease,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,10639402,PubMed,10.1128/iai.68.2.443-448.2000,,,,Cox et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 190,PHI:195,UniProt,Q92213,EMBL,CAA70254,,,3153A,VPS34,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,phosphatidylinositol 3-kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11065354,PubMed,10.1099/00221287-146-11-2755,,,,Bruckmann et al.,2000,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 191,PHI:196,UniProt,Q92210,EMBL,AAC49755,,,ATCC 32354,ADE2,,,,,,,5476,Candida albicans,5476,CAI-7,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,phosphoribosylaminoimidazole carboxylase,"GO:0009405, IMP; GO:0004638",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11254618,PubMed,10.1128/IAI.69.4.2542-2548.2001,,,,Donovan et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 192,PHI:197,UniProt,O93852,EMBL,AAC98913,,,ATCC 10231,ALO1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,"D-arabinono-1,4-lactone oxidase","GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11349062,PubMed,10.1128/IAI.69.6.3939-3946.2001,,,,Huh et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 193,PHI:198,UniProt,P46590,EMBL,AAC41649,,,B792,ALS1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,cell surface protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11967069,PubMed,no data found,,,,Fu et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 194,PHI:198,UniProt,P46590,EMBL,AAC41649,,,B792,ALS1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,primates,9606,Homo sapiens (related: human),,,,,cell surface protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15256583,PubMed,10.1099/mic.0.26943-0,,,Buccal reconstituted human epithelium,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 195,PHI:198,UniProt,P46590,EMBL,AAC41649,,,B792,ALS1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,primates,9606,Homo sapiens (related: human),,,,,cell surface protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15256583,PubMed,10.1099/mic.0.26943-0,,,Human umbilical vein endothelial cells,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 196,PHI:199,UniProt,Q9P304,EMBL,AAF82788,,,Cf4,AOX1,,,,,,,5499,Fulvia fulva,,race 4,leaf mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,alcohol oxidase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB,11277434,PubMed,10.1094/MPMI.2001.14.3.367,Mol Plant Microbe Interact 2001 Mar;14(3):367-77,,,Segers et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 197,PHI:200,UniProt,Q9C1T0,EMBL,BAB40769,,,Mel02010,ARG1,,,,,,,5507,Fusarium oxysporum,,f. sp. melonis race 2 strain Mel02010,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,argininosuccinate lyase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,arginine auxotroph,,,,,,,,,gene disruption; gene complementation,,,TKB; AB,11310747,PubMed,10.1094/MPMI.2001.14.4.580,,,,Namiki et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 198,PHI:201,UniProt,Q9C478,EMBL,AAK00131,,,4224-7-8,AVR-Pita (AVR2-YAMO),,,,,,,318829,Magnaporthe oryzae,,PWL2,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,altered gene expression / gene regulation,,,TKB; MU,11332731,PubMed,10.1094/MPMI.2001.14.5.671,Mol Plant Microbe Interact 2001 Mar;14(3):367-77,,Transposon mutant into promoter,Kang et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 199,PHI:202,UniProt,Q9UW03,EMBL,CAB52402,,,SAS56,BcatrB,,,,,,PHI:544,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,JVK,SH,12324349,PubMed,10.1128/AEM.68.10.4996-5004.2002,,,,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 200,PHI:202,UniProt,Q9UW03,EMBL,CAB52402,,,SAS56,BcatrB,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,ABC transporter,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,TKB,11310744,PubMed,10.1094/MPMI.2001.14.4.562,,,,Schoonbeek et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 201,PHI:203,UniProt,Q9HEP9,EMBL,CAC19871,,,SAS56,BCG1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,G alpha protein subunit,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,different colony morphology,,,,,,,,,gene deletion; gene complementation,,,TKB,11763127,PubMed,10.1094/MPMI.2001.14.11.1293,,,,Gronover et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 202,PHI:203,UniProt,Q9HEP9,EMBL,CAC19871,,,SAS56,BCG1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,G alpha protein subunit,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,different colony morphology,,,,,,,,,gene deletion; gene complementation,,,TKB,11763127,PubMed,10.1094/MPMI.2001.14.11.1293,,,,Gronover et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 203,PHI:204,UniProt,Q9HFT8,EMBL,AAG18428,,,,CaCDC35,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,adenylate cyclase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,11694594,PubMed,10.1091/mbc.12.11.3631,,,,Rocha et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 204,PHI:205,UniProt,Q9URM1,EMBL,CAA21947,,,1161,CaCHS1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,chitin synthase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11251855,PubMed,no data found,,,,Munro et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 205,PHI:206,UniProt,Q9C1S8,EMBL,BAB43821,,,,CaNAG1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GlcN6P deaminase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,11298769,PubMed,10.1046/j.1432-1327.2001.02135.x,,,,Yamada-Okabe et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 206,PHI:207,UniProt,Q9C0N5,EMBL,BAB43813,,,,CaNAG2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GlcNAcP deacetylase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,11298769,PubMed,10.1046/j.1432-1327.2001.02135.x,,,,Yamada-Okabe et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 207,PHI:208,UniProt,Q9C0M1,EMBL,BAB43816,,,,CaNAG5,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GlcNAc kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,11298769,PubMed,10.1046/j.1432-1327.2001.02135.x,,,,Yamada-Okabe et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 208,PHI:209,UniProt,Q9C410,EMBL,AAK09366,,,ATCC10261,CaNRG1,,,,,,,5476,Candida albicans,5476,CAF2-1,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,11737641,PubMed,no data found,,,,Murad et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 209,PHI:210,UniProt,G1U9Y6,EMBL,AAD42978,,,SC5314,CAP1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,adenylate cyclase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,unable to switch from budding to mycelial growth,,,,,,,,,gene disruption; gene complementation,,,TKB,11325951,PubMed,10.1128/JB.183.10.3211-3223.2001,,,,Bahn and Sundstrom,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 210,PHI:211,UniProt,C4YFX2,EMBL,AAB63195,,,W-01,CaTUP1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,11737641,PubMed,no data found,,,,Murad et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 211,PHI:212,UniProt,O74271,EMBL,AAC23929,,,ATCC366,COS1/CHIK1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,histidine kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,wild type,,,,,,,,,gene disruption; gene complementation,,,TKB,11270409,PubMed,10.1080/mmy.39.1.69.74,,,partial complementation,Selitrennikoff et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 212,PHI:213,UniProt,Q9P8W9,EMBL,AAF69795,,,H99,CPA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,cyclophillin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11415984,PubMed,10.1093/embo-reports/kve109,,,,Wang et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 213,PHI:213,UniProt,Q9P8W9,EMBL,AAF69795,,,H99,CPA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,cyclophillin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11415984,PubMed,10.1093/embo-reports/kve109,,,,Wang et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 214,PHI:214,UniProt,Q9UVW7,EMBL,AAF04335,,,SC 5314,DAC1,,,,,,PHI:221; PHI:217,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GlcNAc-6-phosphate deacetylase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11705974,PubMed,10.1128/IAI.69.12.7898-7903.2001,,,,Singh et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 215,PHI:215,UniProt,Q9HGU2,EMBL,AAG01162,,,,FMK1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAP kinase,"GO:0004707, NAS; GO:0009405, IMP; GO:0044409, IMP; GO:0044412, IMP",GO,,loss of pathogenicity,,yes,yes,yes,,,,wild type,wild type,,,,,,,,gene disruption; gene complementation,,,MU; AB,11251832,PubMed,no data found,,,"FUS3/KSS1 homologue; Mutant is unable to attach, penetrate and grow invasively on tomato roots. Phleomycin resistance. Complemented with M. grisea PMK1.",Di Petro et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 216,PHI:215,UniProt,Q9HGU2,EMBL,AAG01162,,,,FMK1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,rodents,10090,Mus musculus (related: house mouse),,,,,MAP kinase,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,,,,,,,,gene disruption; gene complementation,,,MU; AB,11251832,PubMed,no data found,,,"FUS3/KSS1 homologue; Mutant is unable to attach, penetrate and grow invasively on tomato roots. Phleomycin resistance. Complemented with M. grisea PMK1.",Di Petro et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 217,PHI:216,UniProt,Q9C1C6,EMBL,AAK35180,,,,HDC1,,,,,,,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,histone deacetylase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; JA,11449054,PubMed,10.1105/TPC.010168,,,pathogen formerly called Cochliobolus carbonum teleomorph name,Baidyaroy et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 218,PHI:217,UniProt,Q59RW5,EMBL,EAK93243,,,SC5314,HXK1,,,,,,PHI:221; PHI:214,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GlcNAc kinase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11705974,PubMed,10.1128/IAI.69.12.7898-7903.2001,,,,Singh et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 219,PHI:218,UniProt,Q9Y7A1,EMBL,AAD28749,,,M1106,IPC1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,inositol-phosphoryl ceramide synthase 1,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,altered gene expression / gene regulation: downregulation,,,TKB; KHK,11157776,PubMed,10.1101/gad.856001,,,Down regulation of gene expression using an inducible promoter,Luberto et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 220,PHI:219,UniProt,P52496,EMBL,CAA64457,,,ATCC 56884; ATCC 56884,LIG4,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,DNA ligase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11119499,PubMed,10.1128/IAI.69.01.137-147.2001,,,,Andaluz et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 221,PHI:220,UniProt,Q9HFU4,EMBL,AAG10203,,,,MAN1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,phosphomannose isomerase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11359567,PubMed,no data found,,,,Wills et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 222,PHI:220,UniProt,Q9HFU4,EMBL,AAG10203,,,,MAN1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,phosphomannose isomerase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11359567,PubMed,no data found,,,,Wills et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 223,PHI:221,UniProt,Q04802,EMBL,AAF04334,,,SC 5314,NAG1,,,,,,PHI:214; PHI:217,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,glucosamine-6-phosphate deaminase,"GO:0004342; GO:0009405, IGI; GO:0004342",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11705974,PubMed,10.1128/IAI.69.12.7898-7903.2001,,,,Singh et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 224,PHI:222,UniProt,O59939,EMBL,AAD09857,,,CG-14,PELB,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,anthracnose,flowering plants,3435,Persea americana (related: avocado),,,,,pectate lyase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,,yes,,,,,,,,,,,,,gene deletion,,,MU; JK,11497471,PubMed,10.1094/MPMI.2001.14.8.988,,,Tested on Avocado fruits; Partial gene deletion,Yakoby et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 225,PHI:223,UniProt,Q9C441,EMBL,AAK11166,,,,PEP1,,,,,,,169388,Fusarium solani,,94-6-1,root rot,eudicots,3888,Pisum sativum (related: pea),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,functional test in host,,,TKB,11208022,PubMed,10.1007/s00294-003-0428-x,,,NCBI species Nectria haematococca merged into Fusarium solani,Han et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 226,PHI:224,UniProt,Q9C1K0,EMBL,AAK11167,,,,PEP2,,,,,,,169388,Fusarium solani,,94-6-1,root rot,eudicots,3888,Pisum sativum (related: pea),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,functional test in host,,,TKB,11208022,PubMed,10.1007/s00294-003-0428-x,,,NCBI species Nectria haematococca merged into Fusarium solani,Han et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 227,PHI:225,UniProt,Q9C0P7,EMBL,AAK16922,,,77-13-7,PEP5,,,,,,,169388,Fusarium solani,,94-6-1,root rot,eudicots,3888,Pisum sativum (related: pea),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,functional test in host,,,TKB,11208022,PubMed,10.1007/s00294-003-0428-x,,,NCBI species Nectria haematococca merged into Fusarium solani,Han et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 228,PHI:226,UniProt,Q9C1E9,EMBL,AAK16738,,,,PEX6,,,,,,,5462,Colletotrichum lagenaria,,104-T,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,peroxisome biogenesis,"GO:0006631, IMP; GO:0009405, IMP; GO:0044409, IMP",GO,fatty acid metabolism,loss of pathogenicity,,yes,yes,no,,,,,,,,,,,,,gene deletion,,,MU,11487704,PubMed,10.1105/TPC.010084,,,Partial gene deletion. pathogen formerly called Colletotrichum lagenarium,Kimura et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 229,PHI:227,UniProt,Q9HFW0,EMBL,AAG30145,,,H99,PKA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,15972469,PubMed,10.1128/IAI.73.7.3842-3850.2005,,,Tested in G.mellonella caterpillars in the final instar larval stage,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 230,PHI:227,UniProt,Q9HFW0,EMBL,AAG30145,,,H99,PKA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cyclic AMP dependent protein kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,TKB; SH,12438649,PubMed,10.1073/pnas.232568599,,,Tested in C.elegans strain N2 Bristol,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 231,PHI:227,UniProt,Q9HFW0,EMBL,AAG30145,,,H99,PKA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,cyclic AMP dependent protein kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,sterile,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11287622,PubMed,10.1128/MCB.21.9.3179-3191.2001,,,,D'Souza et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 232,PHI:227,UniProt,Q9HFW0,EMBL,AAG30145,,,H99,PKA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,cyclic AMP dependent protein kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,sterile,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11287622,PubMed,10.1128/MCB.21.9.3179-3191.2001,,,,D'Souza et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 233,PHI:227,UniProt,Q9HFW0,EMBL,AAG30145,,,H99,PKA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,15075271,PubMed,10.1128/EC.3.2.413-419.2004,,,Tested in Oregon-R flies,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 234,PHI:228,UniProt,Q9P8P2,EMBL,AAF65220,,,H99,PLB1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,phospholipase B,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11123698,PubMed,no data found,,,,Cox et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 235,PHI:228,UniProt,Q9P8P2,EMBL,AAF65220,,,H99,PLB1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,phospholipase B,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11123698,PubMed,no data found,,,,Cox et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 236,PHI:229,,no data found,GenBank,CAC22481,,,,PLS1,,,,,,,318829,Magnaporthe oryzae,,P1.2,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,tetraspanin,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,no,yes,yes,,,wild type,,,,,,,,,,gene disruption; gene complementation,,,TKB; MU,11391010,PubMed,10.1073/pnas.111132998,,,Plasmid insertion,Clergeot et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 237,PHI:230,UniProt,Q96X31,EMBL,AAK52840,,,,PTK1,,,,,,,53485,Pyrenophora teres,53485,15A,net blotch,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,MAP kinase,"GO:0030437, IMP; GO:0009405, IMP; GO:0044409, IMP; GO:0044412, IMP; GO:0004707, NAS",GO,,loss of pathogenicity,,yes,yes,yes,,absent (no),,reduced,,,,,,,,,gene disruption,,,MU,11204774,PubMed,10.1094/MPMI.2001.14.2.116,,,FUS3/KSS1 homologue,Ruiz-Roldan et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 238,PHI:231,UniProt,Q9C1C2,EMBL,AAK31209,,,,RPK1,,,,,,,5462,Colletotrichum lagenaria,,104-T,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,PKA regulatory subunit,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,,,,,,,,,,,,gene deletion,,,TKB,11605954,PubMed,10.1094/MPMI.2001.14.10.1149,,,Partial gene deletion. pathogen formerly called Colletotrichum lagenarium,Takano et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 239,PHI:232,UniProt,Q9C1R5,EMBL,AAG49739,,,,STE12a,,,,,,,5207,Cryptococcus neoformans,,serotype D strain LP2; serotype D strain LP8,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,regulates mRNA levels,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,mating efficiency reduced,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,11248066,PubMed,10.1073/pnas.061031998,,,,Chang et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 240,PHI:233,UniProt,O74205,EMBL,AAD13811,,,SB111,TOXE,,,,,,,5017,Bipolaris zeicola,,164R10,leaf spot,monocots,4577,Zea mays (related: maize),,,,,transcription factor,"GO:0009405, IMP",GO,toxin biosythesis,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,MU; JA,11698648,PubMed,10.1073/pnas.231491298,,,pathogen formerly called Cochliobolus carbonum teleomorph name,Pedley and Walton,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 241,PHI:234,UniProt,Q96X32,EMBL,AAK49432,,,1/2,UBC2,,,,,,,5270,Ustilago maydis,,,smut (corn),monocots,4577,Zea mays (related: maize),,,,,pheromone adapter protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11580841,PubMed,no data found,,,,Mayorga and Gold,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 242,PHI:235,UniProt,Q96WM3,EMBL,AAK81705,,,H99 (ATCC 208821),VPH1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,vesicular proton pump,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11737651,PubMed,no data found,,,,Erickson et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 243,PHI:236,UniProt,P30601,EMBL,AAC34496,,,wild strain 8656,WdCHS2,,,,,,PHI:237,5970,Exophiala dermatitidis,,Wd8656,phaeohyphomycosis,rodents,10090,Mus musculus (related: house mouse),,,,,chitin synthase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11705928,PubMed,10.1128/IAI.69.12.7517-7526.2001,,,,Wang et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 244,PHI:237,UniProt,P30602,EMBL,AAC35278,,,8656,WdCHS3,,,,,,PHI:236,5970,Exophiala dermatitidis,,Wd8656,phaeohyphomycosis,rodents,10090,Mus musculus (related: house mouse),,,,,chitin synthase,"GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11705928,PubMed,10.1128/IAI.69.12.7517-7526.2001,,,,Wang et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 245,PHI:238,UniProt,Q9Y7A7,EMBL,AAD31436,,,8656,WdPKS1,,,,,,,5970,Exophiala dermatitidis,,8656,phaeohyphomycosis,rodents,10090,Mus musculus (related: house mouse),,,,,polyketide synthase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11179356,PubMed,10.1128/IAI.69.3.1781-1794.2001,,,,Feng et al.,2001,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 246,PHI:239,UniProt,G1UAJ9,EMBL,AAM02905,,,SC5314,ASH1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,12446785,PubMed,10.1128/MCB.22.24.8669-8680.2002,,,,Inglis and Johnson,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 247,PHI:240,UniProt,Q9P880,EMBL,CAB77164,,,SAS 56,BAC,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,adenylate cyclase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,absent (no sporulation in planta),,reduced,,,,,,,,,gene deletion,,,TKB,20569351,PubMed,10.1046/j.1364-3703.2002.00137.x,Klimpel et al. (2002) MOLECULAR PLANT PATHOLOGY 3 (6): 439-450,,,Klimpel et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 248,PHI:241,UniProt,Q9C443,EMBL,AAG60619,,,H99,CAC1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,adenylate cyclase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,mating defective,wild type,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,12455973,PubMed,10.1128/EC.1.1.75-84.2002,,,,Alspaugh et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 249,PHI:241,UniProt,Q9C443,EMBL,AAG60619,,,H99,CAC1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,adenylate cyclase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,mating defective,wild type,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,12455973,PubMed,10.1128/EC.1.1.75-84.2002,,,,Alspaugh et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 250,PHI:242,UniProt,G1UAE0,EMBL,CAC17748,,,,CaTPS2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,trehalose-6-phosphate phosphatase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,11895938,PubMed,10.1128/IAI.70.4.1772-1782.2002,,,,Van Dijck et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 251,PHI:243,UniProt,O93841,EMBL,AAD00894,,,,CHIP6,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose,flowering plants,3435,Persea americana (related: avocado),,,,,sterol glycosyl transferase,"GO:0009405, IMP; GO:0044409",GO,,reduced virulence,,no,yes,,,wild type,,wild type,,,,,,,,,gene deletion,,,TKB; JK,12000454,PubMed,no data found,,,Melanised appressoria. Only macroscopic data provided. No wound inoculation experiment. Tested on Avocado fruits; Partial gene deletion,Kim et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 252,PHI:244,UniProt,Q8J286,EMBL,AAN62846,,,,CLAP1,,,,,,,290576,Colletotrichum lindemuthianum,290576,N9.20,anthracnose,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,copper transporting ATPase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,yes,yes,yes,,,,beige colonies,,,,,,,,,gene deletion,,,TKB; JK,12395188,PubMed,10.1007/s00438-002-0744-8,,,Partial gene deletion,Parisot et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 253,PHI:245,UniProt,Q96VL1,EMBL,CAC47939,,,T5,CPMK1,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,no,yes,yes,,,sterile,,,,,,,,,,gene deletion; gene complementation,,,MU; AC,12026168,PubMed,10.1094/MPMI.2002.15.4.303,Mey et al. (2002) Molecular Plant-Microbe Interactions 15(4): 303-312,tudzyns@uni-muenster.de,FUS3/KSS1 homologue,Mey et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 254,PHI:246,UniProt,Q8J0E1,EMBL,CAC87145,,,T5,CPMK2,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,MU; AC,12406210,PubMed,10.1046/j.1365-2958.2002.03133.x,Mey et al. (2002) Molecular Microbiology 46(2): 305-318,tudzyns@uni-muenster.de,,Mey et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 255,PHI:247,UniProt,P78607,EMBL,CAA71246,,,T5,CPPG1,,,,,,PHI:437,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,endopolygalacturonase,"GO:0009405, IGI; GO:0044412",GO,,loss of pathogenicity,,no,no,yes,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; AC,12135573,PubMed,10.1016/S1087-1845(02)00020-8,Oeser et al. (2002) Fungal Genetics and Biology 36(3): 176-186,tenberg@uni-muenster.de,,Oeser et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 256,PHI:249,UniProt,Q9HFU3,EMBL,AAG13968,,,Guy11,CYP1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,cyclophillin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,11971145,PubMed,10.1105/tpc.010389,,,,Viaud et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 257,PHI:250,UniProt,Q8NJQ3,EMBL,AAM88291,,,C4,DEC1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),,,,,acetoacetate decarboxylase-T-toxin production,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12236595,PubMed,10.1094/MPMI.2002.15.9.883,,,Cochliobolus heterostrophus is pathogen anamorph name,Rose et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 258,PHI:251,UniProt,Q96VA7,EMBL,BAB69488,,,f. sp. cucumerinum strain F9,FGA1,,,,,,,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain F9,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,G alpha protein subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced,,reduced,,,,,,,,,gene disruption,,,TKB; AB,12228810,PubMed,10.1007/s00294-002-0322-y,,,,Jain et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 259,PHI:252,UniProt,Q5A7S7,EMBL,EAK98810,,,SC5314,FKH2,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,primates,9606,Homo sapiens (related: human),,,,,transcription factor,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12455696,PubMed,10.1128/EC.1.5.787-798.2002,,,Forkhead Transcription Factor. Tissue Culture,Benson et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 260,PHI:253,UniProt,Q9C1Q7,EMBL,AAK27436,,,,FOS1,,,,,,,746128,Aspergillus fumigatus,,NRC A-4-56,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,histidine kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB,12146755,PubMed,10.1080/mmy.40.3.259.262,,,,Clemons et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 261,PHI:254,UniProt,Q8TGD1,EMBL,BAB85760,,,Mel02010,FOW1,,,,,,,5507,Fusarium oxysporum,,f. sp. melonis race 2 strain Mel02010,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,mitochondrial carrier protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,wild type,,wild type,,,,,,,,,gene disruption; gene complementation,,,TKB; AB,12172028,PubMed,10.1105/tpc.002576,,,,Inoue et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 262,PHI:255,UniProt,Q9Y8A2,EMBL,AAD43562,,,M-3125,FUM1 (FUM5),,,,,,,5127,Fusarium fujikuroi,,M-3125; 109-R-7,foolish seedling,monocots,4530,Oryza sativa (related: rice),,,,,polyketide synthase,,,fumonisin biosynthesis,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12423021,PubMed,10.1094/MPMI.2002.15.11.1157,,,,Desjardins et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 263,PHI:256,UniProt,Q96TN6,EMBL,AAK52794,,,,GAS1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,appressorial penetration,"GO:0009405, IMP; GO:0044409",GO,,reduced virulence,,no,yes,,,wild type,,wild type,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,12215509,PubMed,10.1105/tpc.003426,,,,Xue et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 264,PHI:257,UniProt,Q9P470,EMBL,AAF74764,,,,GAS2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,appressorial penetration,"GO:0009405, IMP; GO:0044409",GO,,reduced virulence,,no,yes,,,wild type,,wild type,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,12215509,PubMed,10.1105/tpc.003426,,,,Xue et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 265,PHI:258,UniProt,Q96WW9,EMBL,CAC40023,,,R-6380,GPABC1,,,,,,,5128,Fusarium sambucinum,,R6380,rot (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,,ABC transporter,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,11876422,PubMed,10.1094/MPMI.2002.15.2.102,,,Pathogen formerly called Gibberella pulicaris,Fleissner et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 266,PHI:259,UniProt,Q8TGB2,EMBL,AAL83897,,,SC5314,GPI7,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,glycosylphosphatidylinositol modifying enzyme,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11994163,PubMed,no data found,,,,Richard et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 267,PHI:260,UniProt,Q8TG10,EMBL,AAM15960,,,,HDA1,,,,,,,5270,Ustilago maydis,,,smut (corn),monocots,4577,Zea mays (related: maize),,,,,histone deacetylase,,,,unaffected pathogenicity,,,,,,,unable to form mature teliospores,,,,,,,,,,gene disruption; gene complementation,,,MU,12421320,PubMed,no data found,,,,Reichmann et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 268,PHI:261,UniProt,Q86ZF1,EMBL,AAM89498,,,M1,ICL1,,,,,,,5022,Leptosphaeria maculans,,M1,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,isocitrate lyase,"GO:0009405, IMP",GO,glyoxylate,reduced virulence,,,,,,,,unable to metabolise acetate and fatty acids,,,,,,,,,gene deletion; gene complementation,,BH,TKB; AC,12455691,PubMed,10.1128/EC.1.5.719-724.2002.,Idnurm and Howlett (2002) Eukaryotic Cell 1: 719-24,bhowlett@unimelb.edu.au,,Idnurm and Howlett,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 269,PHI:262,UniProt,Q59VQ3,EMBL,EAK94586,,,SC5314,MAD2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,spindle assembly checkpoint,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12100546,PubMed,no data found,,,,Bai et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 270,PHI:263,UniProt,Q8X125,EMBL,AAL50116,,,,MAF1,,,,,,,5462,Colletotrichum lagenaria,,104-T,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced,,wild type,,,,,,,,,gene deletion; gene complementation,,,TKB,12481999,PubMed,10.1094/MPMI.2002.15.12.1268,,,SLT2 homologue. pathogen formerly called Colletotrichum lagenarium,Kojima et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 271,PHI:264,UniProt,Q8J0T6,EMBL,AAN77869,,,BWP17,MDS3,,,,,,,5476,Candida albicans,5476,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,alkaline dependent filamentation,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12524333,PubMed,no data found,,,,Davis et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 272,PHI:265,UniProt,Q8TG24,EMBL,AAL92174,,,H99,MET3,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,ATP sulfurylase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,reduced,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,12177356,PubMed,10.1099/00221287-148-8-2617,,,Function complememtation of yeast mutant,Yang et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 273,PHI:266,UniProt,Q8TG19,EMBL,AAM13670,,,,MGV1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,essential for female fertility and heterokaryon formation,reduced on solid media,,,,,,,,,gene deletion; gene complementation,,,TKB; AB; AC,12423017,PubMed,10.1094/MPMI.2002.15.11.1119,Hou et al. (2002) Molecular Plant-Microbe Interactions 5 (11): 1119-1127,xu@btny.purdue.edu,SLT2 homologue,Hou et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 274,PHI:266,UniProt,Q8TG19,EMBL,AAM13670,,,,MGV1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,MAPK,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,AB; AC,17253976,PubMed,10.1111/j.1462-5822.2006.00887.x,Ramamoorthy et al. (2007) Cellular Microbiology 9(6): 1491-1506,dshah@danforthcenter.org,,Ramamoorthy et al.,2007,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 275,PHI:266,UniProt,Q8TG19,EMBL,AAM13670,,,,MGV1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAPK,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,AB; AC,17253976,PubMed,10.1111/j.1462-5822.2006.00887.x,Ramamoorthy et al. (2007) Cellular Microbiology 9(6): 1491-1506,dshah@danforthcenter.org,,Ramamoorthy et al.,2007,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 276,PHI:267,UniProt,Q9UW87,EMBL,AAD51594,,,,MLT1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,ABC transporter,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,11929516,PubMed,no data found,,,,Theiss et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 277,PHI:268,UniProt,Q96UQ9,EMBL,AAL27626,,,,MST12,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,transcription factor,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,downstream of PMK1,loss of pathogenicity,,no,yes,yes,,wild type,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,11952120,PubMed,10.1094/MPMI.2002.15.3.183,,,Partial gene deletion,Park et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 278,PHI:269,UniProt,Q875L5,EMBL,AAO19639,,,,RAS2,,,,,,,5270,Ustilago maydis,237631,518; 521,smut (corn),monocots,4577,Zea mays (related: maize),,,,,GTP-binding protein,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,aberrant (altered cell morphology),,,,,,,,,gene disruption; gene complementation,,,TKB,12477796,PubMed,10.1128/EC.1.6.954-966.2002,,,,Lee and Kronstad,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 279,PHI:270,UniProt,O42825,EMBL,BAA24262,,,,RHO1,,,,,,,5476,Candida albicans,5476,CAF-3,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GTP-binding protein,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12702298,PubMed,10.1111/j.1567-1364.2002.tb00075.x,,,,Smith et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 280,PHI:271,UniProt,O59924,EMBL,AAC12872,,,,SOD1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,superoxide dismutase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,delayed,,,,,,,,,gene disruption; gene complementation,,,TKB,12427960,PubMed,10.1099/00221287-148-11-3705,,,,Hwang et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 281,PHI:272,UniProt,Q96V71,EMBL,AAL09436,,,C735,SOWgp,,,,,,,5501,Coccidioides immitis,5501,C735,coccidioidomycosis,rodents,10090,Mus musculus (related: house mouse),,,,,adhesin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; JA,12065484,PubMed,10.1128/IAI.70.7.3443-3456.2002,,,,Hung et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 282,PHI:273,UniProt,Q9Y7E5,EMBL,AAD33888,,,,SPT3,,,,,,,5476,Candida albicans,5476,10560-B,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,"mating, sporulation and normal filamentation","GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,TKB,12072450,PubMed,no data found,,,,Laprade et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 283,PHI:274,UniProt,Q7LJU0,EMBL,AAM22494,,,,USX1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,UDP-xylose synthase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,12139628,PubMed,no data found,,,,Moyrand et al.,2002,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 284,PHI:275,UniProt,Q8NKE2,EMBL,AAM22475,,,H99,AOX1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,alternative oxidase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,14500501,PubMed,10.1128/IAI.71.10.5794-5802.2003,,,,Akhter et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 285,PHI:276,UniProt,P49603,EMBL,CAA54909,,,SCHBC1,Bcchs1,,,,,,,40559,Botrytis cinerea,40559,Bd90,grey mold,eudicots,3603,Vitis (no common name found),,,,,chitin synthase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12948512,PubMed,no data found,,,,Soulie et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 286,PHI:277,UniProt,Q6WP53,EMBL,AAQ16572,,,T4,BCP1,,,,,,,40559,Botrytis cinerea,40559,T4,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,cyclophillin,"GO:0009405, IMP",GO,,reduced virulence,,no,,,,wild type,,wild type,,,,,,,,,gene disruption; gene complementation,,,TKB,14651630,PubMed,no data found,,,,Viaud et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 287,PHI:277,UniProt,Q6WP53,EMBL,AAQ16572,,,T4,BCP1,,,,,,,40559,Botrytis cinerea,40559,T4,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,cyclophillin,"GO:0009405, IMP",GO,,reduced virulence,,no,,,,wild type,,wild type,,,,,,,,,gene disruption; gene complementation,,,TKB,14651630,PubMed,no data found,,,,Viaud et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 288,PHI:278,UniProt,Q9C2Y1,EMBL,CAC29255,,,T4,BCPME1,,,,,,PHI:540,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,pectin methylesterase,GO:0030599,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene deletion,,JVK,SH,20565686,PubMed,10.1111/J.1364-3703.2005.00312.X,Kars et al. (2005) MOLECULAR PLANT PATHOLOGY. 6(6) 641-652,,,,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 289,PHI:278,UniProt,Q9C2Y1,EMBL,CAC29255,,,T4,BCPME1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,pectin methylesterase,GO:0030599,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene deletion,,JVK,SH,20565686,PubMed,10.1111/J.1364-3703.2005.00312.X,Kars et al. (2005) MOLECULAR PLANT PATHOLOGY. 6(6) 641-652,,,,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 290,PHI:278,UniProt,Q9C2Y1,EMBL,CAC29255,,,T4,BCPME1,,,,,,PHI:540,40559,Botrytis cinerea,,,grey mold,eudicots,3603,Vitis (no common name found),,,,,pectin methylesterase,GO:0030599,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene deletion,,JVK,SH,20565686,PubMed,10.1111/J.1364-3703.2005.00312.X,Kars et al. (2005) MOLECULAR PLANT PATHOLOGY. 6(6) 641-652,,,,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 291,PHI:278,UniProt,Q9C2Y1,EMBL,CAC29255,,,T4,BCPME1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3750,Malus domestica (related: apple),,,,,pectin methylesterase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,reduced on pectin,,,,,,,,,gene disruption; gene complementation,,,TKB,12744465,PubMed,10.1094/MPMI.2003.16.4.360,,,Malus domestica cv. Granny Smith apple fruits,Valette-Collet et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 292,PHI:278,UniProt,Q9C2Y1,EMBL,CAC29255,,,T4,BCPME1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,pectin methylesterase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,reduced on pectin,,,,,,,,,gene disruption; gene complementation,,,TKB,12744465,PubMed,10.1094/MPMI.2003.16.4.360,,,Virulence was more attenuated on Arabidopsis leaves (ecotype WS) than vine leaves or apple fruits,Valette-Collet et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 293,PHI:278,UniProt,Q9C2Y1,EMBL,CAC29255,,,T4,BCPME1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,pectin methylesterase,GO:0030599,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene deletion,,JVK,SH,20565686,PubMed,10.1111/J.1364-3703.2005.00312.X,Kars et al. (2005) MOLECULAR PLANT PATHOLOGY. 6(6) 641-652,,,,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 294,PHI:278,UniProt,Q9C2Y1,EMBL,CAC29255,,,T4,BCPME1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3603,Vitis (no common name found),,,,,pectin methylesterase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,reduced on pectin,,,,,,,,,gene disruption; gene complementation,,,TKB,12744465,PubMed,10.1094/MPMI.2003.16.4.360,,,Vitis vinifera cv. Chardonnay leaves,Valette-Collet et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 295,PHI:279,UniProt,Q59PD2,EMBL,EAK92427,,,SC5314,CaSPA2,,,,,,,5476,Candida albicans,5476,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,polarity establishment protein,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,12940995,PubMed,no data found,,,,Zheng et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 296,PHI:280,UniProt,Q9HF03,EMBL,AAG36938,,,H99,CCN1,,,,,,,5207,Cryptococcus neoformans,,serotype A strain B-4551,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,cell cycle checkpoint,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene complementation,,,TKB; KHK,12654817,PubMed,10.1128/IAI.71.4.1988-1994.2003,,,Complementation of natural variant strain with wild-type sequence,Chung et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 297,PHI:281,UniProt,P39827,EMBL,CAA81090,,,C792,CDC10,,,,,,,5476,Candida albicans,5476,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,septin protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,reduced,,,,,,,,,gene deletion; gene complementation,,,TKB,12819094,PubMed,10.1128/IAI.71.7.4045-4051.2003,,,,Warenda et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 298,PHI:282,UniProt,Q8NJ85,EMBL,AAM51626,,,,CDC11,,,,,,,5476,Candida albicans,5476,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,septin protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,reduced,,,,,,,,,gene deletion; gene complementation,,,TKB,12819094,PubMed,10.1128/IAI.71.7.4045-4051.2003,,,,Warenda et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 299,PHI:283,UniProt,Q875H9,EMBL,AAO25556,,,,CDC24,,,,,,,5476,Candida albicans,5476,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,polarity establishment protein,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12582118,PubMed,10.1128/EC.2.1.9-18.2003,,,Guanine nucleotide exchange factor Cdc24,Bassilana et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 300,PHI:285,UniProt,Q873Z8,EMBL,AAO49384,,,,CHSV,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,rodents,10090,Mus musculus (related: house mouse),,,,,chitin synthase,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; AB,12492869,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 301,PHI:285,UniProt,Q873Z8,EMBL,AAO49384,,,,CHSV,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,chitin synthase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,no,yes,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; AB,12492869,PubMed,no data found,,,,Madrid et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 302,PHI:286,UniProt,Q874K8,EMBL,AAO73005,,,,CLC-A,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,chloride channel,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,14622414,PubMed,no data found,,,,Zhu and Williamson,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 303,PHI:287,UniProt,Q8J1X6,EMBL,AAN65464,,,,CLNR1,,,,,,,290576,Colletotrichum lindemuthianum,290576,UPS9,anthracnose,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,AREA/NIT2-like global nitrogen regulator,"GO:0009405, IMP; GO:0044412",GO,,loss of pathogenicity,,no,no,yes,,,,,,,,,,,,,gene deletion,,,TKB; JK,12694611,PubMed,no data found,,,Partial gene deletion,Pellier et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 304,PHI:288,UniProt,Q5ABP4,EMBL,EAL00094,,,SC5314,CMP1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,calcineurin A catalytic subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,wild type,,,,,,,,gene disruption; gene complementation,,,TKB,12933882,PubMed,10.1128/IAI.71.9.5344-5354.2003,,,,Bader et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 305,PHI:289,UniProt,Q5ABD7,EMBL,EAK99989,,,SC5314,CNA1,,,,,,,5476,Candida albicans,5476,CAF2-1,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,calcineurin A catalytic subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12753189,PubMed,no data found,,,,Sanglard et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 306,PHI:290,UniProt,Q5AK12,EMBL,EAL03139,,,SC5314,CNB1,,,,,,,5476,Candida albicans,5476,CAF2-1,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,calcineurin B regulatory subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12796287,PubMed,10.1128/EC.2.3.422-430.2003,,,,Blankenship et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 307,PHI:291,UniProt,Q8J1W4,EMBL,CAD10781,,,T5,CPPH1,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,hydrophobin,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,TKB; MU; AC,20569360,PubMed,10.1046/j.1364-3703.2003.00138.x,Mey et al. (2003) MOLECULAR PLANT PATHOLOGY 4 (1): 31-41,tudzyns@uni-muenster.de,,Mey et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 308,PHI:292,UniProt,Q9C1Q9,EMBL,AAK31936,,,,CPRa,,,,,,,5207,Cryptococcus neoformans,,B-4476,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,pheromone receptor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,12933837,PubMed,10.1128/IAI.71.9.4953-4960.2003,,,,Chang et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 309,PHI:293,UniProt,Q9C3Z2,EMBL,AAG53991,,,,CPS1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),,,,,adenylate forming enzymes,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12730371,PubMed,10.1073/pnas.0931375100,,,Cochliobolus heterostrophus is pathogen anamorph name,Lu et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 310,PHI:294,UniProt,Q8NK75,EMBL,BAC11803,,,104-T,CST1,,,,,,,5462,Colletotrichum lagenaria,,104-T,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,transcription factor,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,,,,,,,,,,,,gene deletion,,,TKB,12744460,PubMed,10.1094/MPMI.2003.16.4.315,,,pathogen formerly called Colletotrichum lagenarium,Tsuji et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 311,PHI:295,UniProt,Q7Z8N5,EMBL,AAP87099,,,HvW,CvCPS1,,,,,,,40125,Bipolaris victoriae,,HvW,leaf blight,monocots,4498,Avena sativa (related: oat),,,,,adenylate forming enzymes,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; JK,12730371,PubMed,10.1073/pnas.0931375100,,,pathogen formerly called Cochliobolus victoriae,Lu et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 312,PHI:296,UniProt,Q7Z9J3,EMBL,AAP72037,,,,CZK3,,,,,,,135779,Cercospora zeae-maydis,135779,SCOH1-5,grey leaf spot (maize),monocots,4577,Zea mays (related: maize),,,,,MAP kinase kinase kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,defective,,increased,,,,,,,,,gene disruption; gene complementation,,,MU,12971599,PubMed,10.1094/MPMI.2003.16.9.760,,,,Shim and Dunkle,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 313,PHI:300,UniProt,Q6XPX0,EMBL,AAO91808,,,,FGB1,,,,,,,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain F9,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,G beta protein subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; AB,12695847,PubMed,10.1007/s00294-003-0372-9,,,,Jain et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 314,PHI:301,UniProt,Q8J2N0,EMBL,AAN32715,,,O-685,foSNF1,,,,,,,5507,Fusarium oxysporum,,O-685,vascular wilt,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,,protein kinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,reduced virulence,,no,yes,yes,,,,wild type,,,,,,,,,gene disruption,,,TKB; AB,12845476,PubMed,10.1007/s00294-003-0419-y,,,,Ospina-Giraldo et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 315,PHI:301,UniProt,Q8J2N0,EMBL,AAN32715,,,O-685,foSNF1,,,,,,,5507,Fusarium oxysporum,,O-685,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,protein kinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,reduced virulence,,no,yes,yes,,,,wild type,,,,,,,,,gene disruption,,,TKB; AB,12845476,PubMed,10.1007/s00294-003-0419-y,,,,Ospina-Giraldo et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 316,PHI:303,UniProt,Q7Z9Z4,EMBL,AAP50501,,,,GAT1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GATA transcription factor for nitrogen metabolism,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,14617156,PubMed,no data found,,,,Limjindaporn et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 317,PHI:304,UniProt,Q86ZP4,EMBL,AAP12366,,,Z3639,GzCPS1,,,,,,,5518,Fusarium graminearum,229533,Z3936,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,adenylate forming enzymes,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; AB,12730371,PubMed,10.1073/pnas.0931375100,Lu et al. (2003) Proc Natl Acad Sci USA 100(10): 5980-5985,bgt1@cornell.edu,,Lu et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 318,PHI:305,UniProt,P0CT06,EMBL,AAN28719,,,Guy11,ICL1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,isocitrate lyase,"GO:0004451, NAS; GO:0009405, IMP; GO:0044409, IMP; GO:0009847, IMP",GO,,reduced virulence,,yes,yes,,,,,,delayed,,,,,,,,gene deletion,,,TKB; MU,12622815,PubMed,no data found,,,,Wang et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 319,PHI:306,UniProt,O13359,EMBL,AAB80929,,,WO-1,KEX2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,kexin gene,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12419804,PubMed,10.1074/jbc.M209713200,,,,Newport et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 320,PHI:308,UniProt,Q86ZC3,EMBL,CAD43731,,,FB1,KPP6,,,,,,,5270,Ustilago maydis,559306,FB1; FB2; SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409",GO,,reduced virulence,,,yes,,,,,,,,,,,,,,gene deletion,,,TKB,12727886,PubMed,10.1093/emboj/cdg198,,,FUS3/KSS1 homologue,Brachmann et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 321,PHI:309,UniProt,I1RQN9,EMBL,AAL73403,,,,MAP1 (related: GPMK1),,,,,,,5518,Fusarium graminearum,,16A,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,no,yes,yes,,wild type,sterile,,wild type,,,,,,,,gene deletion,,,TKB; AB,20569395,PubMed,10.1046/j.1364-3703.2003.00183.x,Urban M et al. (2003) MOLECULAR PLANT PATHOLOGY 4 (5): 347-359,,FUS3/KSS1 homologue,Urban et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 322,PHI:309,UniProt,I1RQN9,EMBL,AAL73403,,,,MAP1 (related: GPMK1),,,,,,,5518,Fusarium graminearum,,16A,Fusarium ear blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,no,yes,yes,,wild type,sterile,,wild type,,,,,,,,gene deletion,,,TKB; AB,20569395,PubMed,10.1046/j.1364-3703.2003.00183.x,Urban M et al. (2003) MOLECULAR PLANT PATHOLOGY 4 (5): 347-359,,FUS3/KSS1 homologue,Urban et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 323,PHI:309,UniProt,I1RQN9,EMBL,AAL73403,,,,MAP1 (related: GPMK1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,AB; AC,17253976,PubMed,10.1111/j.1462-5822.2006.00887.x,Ramamoorthy et al. (2007) Cellular Microbiology 9(6): 1491-1506,dshah@danforthcenter.org,,Ramamoorthy et al.,2007,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 324,PHI:309,UniProt,I1RQN9,EMBL,AAL73403,,,,MAP1 (related: GPMK1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,MAP kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,AB; AC,17253976,PubMed,10.1111/j.1462-5822.2006.00887.x,Ramamoorthy et al. (2007) Cellular Microbiology 9(6): 1491-1506,dshah@danforthcenter.org,,Ramamoorthy et al.,2007,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 325,PHI:3517,UniProt,I1RQN9,EMBL,AAL73403,,,16A,MAP1 (related: GPMK1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Landsberg erecta,,,inflorescence,MAP kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; biochemical analysis,,,AB; AC,18179606,PubMed,10.1111/j.1469-8137.2007.02333.x,Cuzick et al. (2008) New Phytologist 177(4): 990-1000,kim.hammond-kosack@bbsrc.ac.uk,FUS3/KSS1 homologue,Cuzick et al.,2008,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 326,PHI:3517,UniProt,I1RQN9,EMBL,AAL73403,,,16A,MAP1 (related: GPMK1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spike,MAP kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; biochemical analysis,,,AB; AC,18179606,PubMed,10.1111/j.1469-8137.2007.02333.x,Cuzick et al. (2008) New Phytologist 177(4): 990-1000,kim.hammond-kosack@bbsrc.ac.uk,FUS3/KSS1 homologue,Cuzick et al.,2008,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 327,PHI:310,UniProt,Q9C1I7,EMBL,AAK15314,,,IPO323,MgAtr4,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,ABC transporter,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12906113,PubMed,10.1094/MPMI.2003.16.8.689,,,,Stergiopoulos,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 328,PHI:311,UniProt,Q8NK86,EMBL,BAC01165,,,Guy11,MGB1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,G beta protein subunit,"GO:0009405, IMP; GO:0044409, IMP; GO:0044412, IMP",GO,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,14507377,PubMed,no data found,,,Partial gene deletion,Nishimura et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 329,PHI:313,UniProt,Q873Y1,EMBL,AAO61669,,,,MPK1,,,,,,,5207,Cryptococcus neoformans,,JEC43,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,12787363,PubMed,10.1046/j.1365-2958.2003.03508.x,,,SLT2 homologue,Kraus et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 330,PHI:314,UniProt,Q9P413,EMBL,AAF93178,,,,PAC1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold; stem rot,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12971602,PubMed,10.1094/MPMI.2003.16.9.785,,,,Rollins,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 331,PHI:314,UniProt,Q9P413,EMBL,AAF93178,,,,PAC1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold; stem rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12971602,PubMed,10.1094/MPMI.2003.16.9.785,,,,Rollins,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 332,PHI:315,UniProt,Q870A3,EMBL,AAM95700,,,,PacC,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,rodents,10090,Mus musculus (related: house mouse),,,,,pH signalling transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; AB,12694620,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 333,PHI:315,UniProt,Q870A3,EMBL,AAM95700,,,,PacC,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,pH signalling transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; AB,12694620,PubMed,no data found,,,,Caracuel et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 334,PHI:316,UniProt,Q8RYB2,EMBL,AAP55639,,,H30P04,PiGPB1,,,,,,,4787,Phytophthora infestans,,NL-88069; METV-618,late blight,eudicots,4113,Solanum tuberosum (related: potato),,,,,G beta protein subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,altered gene expression / gene regulation: silencing,,,TKB,14555479,PubMed,10.1128/EC.2.5.971-977.2003,,,,Latijnhouwers et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 335,PHI:317,UniProt,Q8J2P6,EMBL,AAN17787,,,,RHBA,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,nutrient signalling,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,12704156,PubMed,10.1128/IAI.71.5.2819-2826.2003,,,,Panepinto et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 336,PHI:318,UniProt,Q9C0N4,EMBL,AAK31919,,,NYS 155B,SOD1,,,,,,,552467,Cryptococcus bacillisporus,1441719,NIH 444,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),,,,,superoxide dismutase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,wild type,wild type,wild type,,,,,,,,,gene deletion; gene complementation,,,TKB; SH,12622821,PubMed,no data found,,,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,Narasipura et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 337,PHI:318,UniProt,Q9C0N4,EMBL,AAK31919,,,NYS 155B,SOD1,,,,,,PHI:420,552467,Cryptococcus bacillisporus,1441719,NIH 444,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),,,,,superoxide dismutase,"GO:0009405, IGI",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene deletion; gene complementation,,,TKB; SH,15752200,PubMed,10.1111/j.1365-2958.2005.04503.x,,,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,Narasipura et al.,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 338,PHI:319,UniProt,Q875L6,EMBL,AAO19638,,,,SQL2,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,guanine nucleotide exchange factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12796306,PubMed,10.1128/EC.2.3.609-617.2003,,,,Muller at al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 339,PHI:320,UniProt,Q8TGW9,EMBL,AAL54912,,,ATCC10231,SSN6,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,global transcriptional co-repressor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12581357,PubMed,no data found,,,,Hwang et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 340,PHI:321,UniProt,Q875G7,EMBL,CAD59444,,,ATCC 2001,STE12,,,,,,,5478,Candida glabrata,,,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,14622417,PubMed,no data found,,,,Calcagno et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 341,PHI:322,UniProt,Q875L7,EMBL,AAN46744,,,Guy11,TPS1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,trehalose-6-phosphate synthase,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,,,,,,,,,,,,gene deletion,,,TKB; MU,12514128,PubMed,10.1128/EC.2.1.9-18.2003,,,Partial gene deletion,Foster et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 342,PHI:323,UniProt,Q7ZA48,EMBL,AAO63562,,,150-1,VFGLU1,,,,,,,93591,Lecanicillium fungicola,,,mycopathogen,basidiomycetes,5341,Agaricus bisporus (related: cultivated mushroom),,,,,"beta-1,6-glucanase","GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; MU,12892639,PubMed,no data found,,,,Amey et al.,2003,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 343,PHI:324,UniProt,Q5QEY0,EMBL,AAU05130,,,H99,ACA1,,,,,,,5207,Cryptococcus neoformans,235443,serotype A strain H99; serotype A strain KN99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,adenylyl cyclase-associated protein,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,15590822,PubMed,10.1128/EC.3.6.1476-1491.2004,,,,Bahn et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 344,PHI:325,UniProt,Q6ZX14,EMBL,CAG28797,,,Guy11,ACE1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,"effector protein, polyketide synthase",,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,MU,15319478,PubMed,10.1105/tpc.104.022715,,,Partial gene deletion,Bohnert et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 345,PHI:326,UniProt,Q700F1,EMBL,CAF34431,,,ATCC 2001,ACE2,,,,,,,5478,Candida glabrata,,,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15075283,PubMed,10.1128/EC.3.2.546-552.2004,,,,Kamran et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 346,PHI:328,UniProt,Q5G7L3,EMBL,AAW63763,,,Maks9,ATR13,,,,,,,272952,Hyaloperonospora arabidopsidis,,,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,other evidence,,,TKB; MU,15591208,PubMed,10.1126/science.1104022,,,Functional analysis by biolistic transformation of Arabidopsis. Maks9 isolate of H. parasitica,,,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 347,PHI:329,UniProt,Q8J0E3,EMBL,CAD43406,,,T4,BcPLS1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,tetraspanin,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,,,,,,,,,,,,gene deletion,,,TKB; MU,14731267,PubMed,no data found,,,,Gourgues et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 348,PHI:329,UniProt,Q8J0E3,EMBL,CAD43406,,,T4,BcPLS1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3764,Rosa (no common name found),,,,,tetraspanin,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,,,,,,,,,,,,gene deletion,,,TKB; MU,14731267,PubMed,no data found,,,,Gourgues et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 349,PHI:329,UniProt,Q8J0E3,EMBL,CAD43406,,,T4,BcPLS1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,tetraspanin,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,,,,,,,,,,,,gene deletion,,,TKB; MU,14731267,PubMed,no data found,,,,Gourgues et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 350,PHI:329,UniProt,Q8J0E3,EMBL,CAD43406,,,T4,BcPLS1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,39473,Cucumis anguria (related: gherkin),,,,,tetraspanin,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,,,,,,,,,,,,,,gene deletion,,,TKB; MU,14731267,PubMed,no data found,,,,Gourgues et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 351,PHI:330,UniProt,Q70Q35,EMBL,CAD88591,,,,BcSOD1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,Cu-Zn-superoxide dismutase,"GO:0009405, IMP; GO:0004784",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; MU,,Not in PubMed,10.1046/J.1364-3703.2004.00201.X,Rolke et al. (2004) MOLECULAR PLANT PATHOLOGY 5 (1): 17-27,,,Rolke et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 352,PHI:331,UniProt,Q59RR0,EMBL,EAK93180,,,SC5314,CaACE2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB,15255906,PubMed,10.1111/j.1365-2958.2004.04185.x,,,,Kelly et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 353,PHI:332,UniProt,Q75T35,EMBL,BAD04045,,,,CAC1,,,,,,,5462,Colletotrichum lagenaria,,104-T,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,adenylate cyclase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,no,yes,yes,,,,,,,,,,,,,gene deletion,,,TKB,15597741,PubMed,10.1094/MPMI.2004.17.12.1355,,,Partial gene deletion. pathogen formerly called Colletotrichum lagenarium,Yamauchi et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 354,PHI:333,UniProt,Q5Y9C4,EMBL,AAV27296,,,CAF2,CaEcm33,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GPI-anchored protein,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15470113,PubMed,10.1099/mic.0.27320-0,,,,Martinez-Lopez et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 355,PHI:334,UniProt,Q6XSF5,EMBL,AAO25585,,,,CGB1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),,,,,G beta protein subunit,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,reduced,female sterile,wild type,conidia do not germinate,,,,,,,,gene disruption,,,TKB,15590838,PubMed,10.1128/EC.3.6.1653-1663.2004,,,Cochliobolus heterostrophus is pathogen anamorph name,Ganem et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 356,PHI:335,UniProt,Q9HEQ8,EMBL,AAG28884,,,,CGRA,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,ribosome synthesis,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; MU,15271935,PubMed,10.1128/IAI.72.8.4731-4740.2004,,,,Bhabhra et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 357,PHI:336,UniProt,Q5YCX0,EMBL,AAT77182,,,,CHS2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,chitin synthase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; AB,15470098,PubMed,10.1099/mic.0.27236-0,,,,Martin-Udiroz et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 358,PHI:337,UniProt,Q5YCW8,EMBL,AAT77184,,,,CHS7,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,chitin synthase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; AB,15470098,PubMed,10.1099/mic.0.27236-0,,,,Martin-Udiroz et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 359,PHI:338,UniProt,Q6X269,EMBL,AAP94020,,,,CLB2,,,,,,,5270,Ustilago maydis,,,smut (corn),monocots,4577,Zea mays (related: maize),,,,,B-type cyclin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,altered gene expression / gene regulation,,,TKB; MU,14679309,PubMed,10.1242/jcs.00877,,,,Garcia-Muse et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 360,PHI:339,UniProt,Q96VL3,EMBL,CAC41973,,,beta,CLPT1,,,,,,,290576,Colletotrichum lindemuthianum,290576,race beta,anthracnose,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,GTPase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene mutation: characterised,,,TKB; JK,15615776,PubMed,10.1242/jcs.01616,,,Site directed mutagenesis,Siriputthaiwan et al.,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 361,PHI:340,UniProt,Q71S08,EMBL,AAQ14858,,,,CPCA,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,amino acid biosynthesis,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15101984,PubMed,10.1111/j.1365-2958.2004.04015.x,,,,Krappmann et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 362,PHI:341,UniProt,Q75T36,EMBL,BAD04044,,,,CPK1,,,,,,,5462,Colletotrichum lagenaria,,104-T,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,PKA catalytic subunit,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes (defective),yes,,,,,,,,,,,,,gene disruption,,,TKB,15597741,PubMed,10.1094/MPMI.2004.17.12.1355,,,"gene disruption (TAG-KO), no complementation.Non-functional appressoria. pathogen formerly called Colletotrichum lagenarium",Yamauchi et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 363,PHI:342,UniProt,Q875L0,EMBL,AAO27796,,,,CpMK1,,,,,,,5116,Cryphonectria parasitica,,,blight (chestnut),eudicots,134033,Castanea dentata (related: american chestnut),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation; biochemical evidence,,,TKB; MU,14982623,PubMed,10.1111/j.1365-2958.2004.03919.x,,,HOG1 homologue,Park et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 364,PHI:343,UniProt,Q6B971,EMBL,AAT92283,,,,CPRGS-1,,,,,,,5116,Cryphonectria parasitica,,,blight (chestnut),eudicots,134033,Castanea dentata (related: american chestnut),,,,,G-protein signalling molecule,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,TKB; MU,15590820,PubMed,10.1128/EC.3.6.1454-1463.2004,,,,Segers et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 365,PHI:344,UniProt,Q8J0I5,EMBL,CAD21519,,,T5,CPTF1,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; MU; AC,15077671,PubMed,10.1094/MPMI.2004.17.4.383,Nathues et al. (2004) Molecular Plant-Microbe Interactions 17(4): 383-393,tudzyns@uni-muenster.de,,Nathues et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 366,PHI:345,UniProt,Q69FA8,EMBL,AAR06257,,,B3501,CRG1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,G-protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,15302835,PubMed,10.1128/EC.3.4.1028-1035.2004,,,,Wang et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 367,PHI:346,UniProt,Q8J214,EMBL,AAN10186,,,,CRU1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2; SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,cell cycle,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB,15316079,PubMed,10.1242/jcs.01304,,,,Castillo-Lluva et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 368,PHI:348,UniProt,Q59PJ5,EMBL,EAK92385,,,SC5314,CSH3,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,amino acid transporter,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,14756779,PubMed,10.1046/j.1365-2958.2003.03845.x,,,,Martinez et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 369,PHI:350,UniProt,Q6T7C1,EMBL,AAR06609,,,70-15,EMP1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,extracellular protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; MU,15055545,PubMed,no data found,,,Partial gene deletion,Ahn et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 370,PHI:351,UniProt,Q1G354,EMBL,ABF60662,,,,FcABC1,,,,,,,5516,Fusarium culmorum,5516,IBT8336,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,ABC transporter,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,no,yes,,,,,,,,,,,,,gene deletion,,,TKB; AB,,Not in PubMed,10.1016/j.pmpp.2004.09.005,"Skov et al. (2004) PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY 64(5), 245-254",,,Skov et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 371,PHI:352,UniProt,Q7Z868,EMBL,CAD79488,,,521,GLO1,,,,,,,5270,Ustilago maydis,,,smut (corn),monocots,4577,Zea mays (related: maize),,,,,glyoxal oxidase,"GO:0009405, IMP",GO,,loss of pathogenicity,yes,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15578222,PubMed,10.1007/s00438-004-1085-6,,,,Leuthner et al.,2005,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 372,PHI:353,UniProt,Q6EH42,EMBL,AAQ94737,,,,GNA1,,,,,,,13684,Parastagonospora nodorum,,,glume blotch,monocots,4564,Triticum (related: wheat),,,,,G alpha protein subunit,"GO:0009405, IMP; GO:0044409",GO,,reduced virulence,,no,yes,,,absent (no sporulation),,,,,,,,,,,gene disruption,,RO,TKB; MU; AC,15141949,PubMed,10.1094/MPMI.2004.17.5.456,Solomon et al. (2004) Mol Plant Microbe Interact. 17(5):456-466,psolomon@murdoch.edu.au,,Solomon et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 373,PHI:354,UniProt,Q8TFX6,EMBL,CAC81805,,,ATCC46645,GPAB,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,G alpha protein subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; MU,15322014,PubMed,10.1128/IAI.72.9.5193-5203.2004,,,,Liebmann et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 374,PHI:355,UniProt,I1RNS1,Broad,FG05658,,,PH-1; NRRL 31084,GzmetE,,,,,,,5518,Fusarium graminearum,229533,Z03643,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,homoserine O-acetyltransferase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; AB; MU,15378266,PubMed,10.1007/s00294-004-0528-2,,,,Han et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 375,PHI:356,UniProt,Q9UW16,EMBL,AAK98783,,,,HEX1,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,woronin body assembly,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,reduced virulence,,,yes,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15155882,PubMed,10.1105/tpc.020677,,,Partial gene deletion,Soundararajan et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 376,PHI:357,UniProt,Q5ABE2,EMBL,EAL00089,,,SC5314,HGC1,,,,,,,5476,Candida albicans,5476,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,G1 cyclin-related protein,"GO:0009405, IMP",GO,cell signalling,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,15071502,PubMed,10.1038/sj.emboj.7600195,,,,Zheng et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 377,PHI:358,UniProt,Q6SSJ3,EMBL,AAR29084,,,,ILV2,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,acetolactate synthase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,15133116,PubMed,10.1099/mic.0.26928-0,,,,Kingsbury et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 378,PHI:359,UniProt,G1UA43,EMBL,AAK14386,,,,KER1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,pH-regulated lysine/glutamic-acid-rich protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,15289560,PubMed,10.1099/mic.0.26339-0,,,,Galan et al.,2004,,,PHI-base Vers.3.3,2005-05-04,RRes,,,,,,,,,,,,,
,,Record 379,PHI:360,UniProt,Q5K995,EMBL,AAW46354,,,JEC21,KIN1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,serine/threonine protein kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,15469513,PubMed,10.1111/j.1365-2958.2004.04310.x,,,,Mylonakis et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 380,PHI:360,UniProt,Q5K995,EMBL,AAW46354,,,JEC21,KIN1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,15469513,PubMed,10.1111/j.1365-2958.2004.04310.x,,,Tested in C.elegans strain N2 Bristol,,,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 381,PHI:361,UniProt,Q5AEW4,EMBL,EAL01265,,,SC5314,KRE5,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,glucosyltransferase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,15590817,PubMed,10.1128/EC.3.6.1423-1432.2004,,,,Herrero et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 382,PHI:362,UniProt,Q4WUL6,EMBL,CAC48042,,,ATCC46645,LYSF,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,homoaconitase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15052376,PubMed,10.1007/s00203-004-0667-3,,,,Liebmann et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 383,PHI:364,UniProt,Q59X54,EMBL,EAK95175,,,SC5314,MIT1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GDP-mannose: inositol-phospho-ceramide mannose transferase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,15347680,PubMed,10.1074/jbc.M405534200,,,,Mille et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 384,PHI:365,UniProt,Q5J4D6,EMBL,AAS91580,,,,MLS1,,,,,,,13684,Parastagonospora nodorum,,,glume blotch,monocots,4564,Triticum (related: wheat),,,,,malate synthase,"GO:0009405, IMP; GO:0044409, IMP; GO:0004474, NAS",GO,,loss of pathogenicity,,yes,yes,no,,,,,,,,,,,,,gene disruption; gene complementation,,RO,TKB; MU; AC,15306011,PubMed,10.1111/j.1365-2958.2004.04178.x,Solomon et al. (2004) Mol Microbiol. 53(4): 1065-1073,psolomon@murdoch.edu.au,,Solomon et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 385,PHI:366,UniProt,Q6Q8B9,EMBL,AAS86162,,,Guy11,MMT1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,metallothionein,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,reduced,,,,,,,,,,,gene disruption,,,TKB; MU,15155887,PubMed,10.1105/tpc.021279,,,,Tucker et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 386,PHI:366,UniProt,Q6Q8B9,EMBL,AAS86162,,,Guy11,MMT1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,metallothionein,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,no,,reduced,,,,,,,,,,,gene disruption,,,TKB; MU,15155887,PubMed,10.1105/tpc.021279,,,,Tucker et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 387,PHI:367,UniProt,Q697D5,EMBL,AAT81148,,,,MRB1,,,,,,,5270,Ustilago maydis,,,smut (corn),monocots,4577,Zea mays (related: maize),,,,,mitochondrial matrix protein,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,no,yes,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15273296,PubMed,10.1105/tpc.104.022657,,,,Bortfeld et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 388,PHI:368,UniProt,Q9P927,EMBL,AAF66693,,,SC5314,NOT4,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,ubiquitin-conjugation,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,14702416,PubMed,10.1099/mic.0.26792-0,,,,Krueger et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 389,PHI:369,UniProt,Q8RYB4,EMBL,AAL11436,,,88069,PiGPA1,,,,,,,4787,Phytophthora infestans,,,late blight,eudicots,4113,Solanum tuberosum (related: potato),,,,,G alpha protein subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,altered gene expression / gene regulation: silencing,,,TKB; MU,14763970,PubMed,no data found,,,,Latijnhouwers et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 390,PHI:370,UniProt,Q8NIK9,EMBL,AAM74047,,,JEC21,PKA2,,,,,,,5207,Cryptococcus neoformans,,serotype D strain JEC155,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,cyclic AMP dependent protein kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,SH; KHK,14871933,PubMed,10.1128/EC.3.1.14-26.2004,,,,Hicks et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 391,PHI:371,UniProt,Q8J129,EMBL,CAC82611,,,ATCC46645,PKAC1,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,PKA catalytic subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; MU,15322014,PubMed,10.1128/IAI.72.9.5193-5203.2004,,,,Liebmann et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 392,PHI:372,UniProt,Q9HFV9,EMBL,AAG30146,,,H99,PKR1,,,,,,,5207,Cryptococcus neoformans,,serotype A strain M049,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption,,,SH; KHK,15503029,PubMed,10.1007/s00294-004-0529-1,,,,Wang et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 393,PHI:372,UniProt,Q9HFV9,EMBL,AAG30146,,,H99,PKR1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,regulatory protein,"GO:0009405, IMP",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption,,AI,TKB; SH,12438649,PubMed,10.1073/pnas.232568599,,,Tested in C.elegans strain N2 Bristol,,,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 394,PHI:372,UniProt,Q9HFV9,EMBL,AAG30146,,,H99,PKR1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,,"GO:0009405, IMP",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,15075271,PubMed,10.1128/EC.3.2.413-419.2004,,,Tested in Oregon-R flies,,,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 395,PHI:373,UniProt,Q59TT3,EMBL,EAK93902,,,SC5314,PLD1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,phospholipase D1,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,11283284,PubMed,10.1099/00221287-147-4-879,,,,Hube et al.,2001,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 396,PHI:375,UniProt,Q876Z6,EMBL,BAC55015,,,Mel02010,REN1,,,,,,,5507,Fusarium oxysporum,,f. sp. melonis race 2 strain Mel02010,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,transcription regulator,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB; AB,15020411,PubMed,no data found,,,,Ohara et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 397,PHI:376,UniProt,Q8NKF8,EMBL,AAM21494,,,H99,SCH9,,,,,,,5207,Cryptococcus neoformans,,serotype A strain M049,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,protein kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; SH,15503029,PubMed,10.1007/s00294-004-0529-1,,,,Wang et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 398,PHI:376,UniProt,Q8NKF8,EMBL,AAM21494,,,H99,SCH9,,,,,,,5207,Cryptococcus neoformans,,serotype A strain M049,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; SH,15503029,PubMed,10.1007/s00294-004-0529-1,,,,Wang et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 399,PHI:377,UniProt,E9QYP0,EMBL,AAT84594,,,,SIDA,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,L-ornithine-N-5-monooxygenase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15504822,PubMed,10.1084/jem.20041242,,,,Schrettl et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 400,PHI:378,UniProt,Q59KY8,EMBL,EAK91146,,,SC5314,SIT4,,,,,,,5476,Candida albicans,5476,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,protein phosphatase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,14731272,PubMed,no data found,,,,Lee et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 401,PHI:379,UniProt,Q709E2,EMBL,CAE55866,,,Fol007,SIX1,,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; AB,15387816,PubMed,10.1111/j.1365-2958.2004.04177.x,,,Secreted 12 kDa cysteine-rich protein. Interaction with I-3 resistance gene,Rep et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 402,PHI:380,UniProt,Q5A4X5,EMBL,EAK97884,,,SC5314,SKN7,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,response regulator,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,15039366,PubMed,10.1128/IAI.72.4.2390-2394.2004,,,,Singh et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 403,PHI:382,UniProt,Q4P5N0,EMBL,AAM97788,,,,SMU1,,,,,,,5270,Ustilago maydis,,1/52,smut (corn),monocots,4577,Zea mays (related: maize),,,,,serine/threonine kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB,14871948,PubMed,10.1128/EC.3.1.180-189.2004,,,STE20 homologue,Smith et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 404,PHI:383,UniProt,Q5AD07,EMBL,EAL00626,,,SC5314,SOD5,,,,,,,5476,Candida albicans,5476,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,superoxide dismutase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,14617819,PubMed,10.1091/mbc.E03-03-0179,,,,Martchenko et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 405,PHI:384,UniProt,Q6RXX2,EMBL,AAS48112,,,,SPE3-LYS9,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,chimeric spermidine synthase/saccharopine dehydrogenase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; SH,15189996,PubMed,10.1128/EC.3.3.752-763.2004,,,,Kingsbury et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 406,PHI:385,UniProt,Q875J4,EMBL,AAO18659,,,,tgaA,,,,,,,29875,Trichoderma virens,,,mycopathogen,basidiomycetes,39291,Agroathelia rolfsii (no common name found),,,,,G alpha protein subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; MU,14711686,PubMed,10.1128/AEM.70.1.542-549.2004,,,,Mukherjee et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 407,PHI:386,UniProt,Q7Z9J6,EMBL,AAP68994,,,H99,TSA1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,thiol peroxidase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,14982637,PubMed,10.1111/j.1365-2958.2004.03921.x,,,,Missal et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 408,PHI:387,UniProt,Q96VU5,EMBL,AAK95561,,,B-4500,UGD1,,,,,,,5207,Cryptococcus neoformans,214684,serotype D strain JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,UDP-glucose dehydrogenase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,15383535,PubMed,10.1074/jbc.M408889200,,,,Griffith et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 409,PHI:389,UniProt,O13395,EMBL,AAB84285,,,518,Umchs6,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,chitin synthase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,14990260,PubMed,10.1016/j.resmic.2003.11.005,,,,Garcera-Teruel et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 410,PHI:390,UniProt,Q8TGV2,EMBL,AAL79830,,,,WdCHS5,,,,,,,5970,Exophiala dermatitidis,,,phaeohyphomycosis,rodents,10090,Mus musculus (related: house mouse),,,,,chitin synthase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; MU,14871935,PubMed,10.1128/EC.3.1.40-51.2004,,,,Liu et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 411,PHI:391,UniProt,Q874F3,EMBL,BAC67162,,,P-2b,ABC2,,,,,,,318829,Magnaporthe oryzae,,P-2b,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,ABC transporter,GO:0042626,GO,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption,,,TKB; MU,,Not in PubMed,10.1016/j.pestbp.2004.07.007,"Lee et al. (2005) PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 81(1) 13-23.",,,Lee et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 412,PHI:392,UniProt,P46592,EMBL,CAA61538,,,Cai-4,CaMNT2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,"alpha-1,2-mannosyltransferase","GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15519997,PubMed,10.1074/jbc.M411413200,,,,Munro et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 413,PHI:393,UniProt,Q5K2R7,EMBL,CAH04535,,,T5,CpCOT1,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,serine/threonine protein kinase,"GO:0009405, IMP; GO:0044409, IMP; GO:0032147, NAS",GO,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU; AC,15670709,PubMed,10.1016/j.fgb.2004.10.005,Scheffer et al. (2005) Fungal Genetics and Biology 42(2): 107-118,tudzyns@uni-muenster.de,,Scheffer et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 414,PHI:394,UniProt,Q8NKE9,EMBL,AAM21640,,,,CRK1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,CDK-related kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,yes,,,,,,,,,,,,,,,,gene deletion,,,TKB,15601825,PubMed,10.1101/gad.314904,,,IME2 homologue,Garrido et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 415,PHI:395,UniProt,Q65YU2,EMBL,BAD44729,,,,FGA2,,,,,,,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain F9,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,G alpha protein subunit,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB; AB,15668015,PubMed,10.1016/j.femsle.2004.12.009,,,,Jain et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 416,PHI:397,UniProt,Q5RLJ7,EMBL,AAV64894,,,H99,LAC2,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,laccase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,15643074,PubMed,10.1128/EC.4.1.190-201.2005,,,,Pukkila-Worley et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 417,PHI:398,UniProt,Q00202,EMBL,CAA87390,,,,PacC,,,,,,,162425,Aspergillus nidulans,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,pH signalling transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene mutation: characterised,,,TKB; MU,15686555,PubMed,10.1111/j.1365-2958.2004.04472.x,,,,Bignell et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 418,PHI:399,UniProt,Q59X23,EMBL,EAK95207,,,SC5314,PMT4,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,mannosyltransferase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,15659169,PubMed,10.1111/j.1365-2958.2004.04401.x,,,,Prill et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 419,PHI:401,UniProt,O13401,EMBL,AAB86583,,,,SOD2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,manganese superoxide dismutase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12898709,PubMed,10.1002/yea.1004,,,,Hwang et al.,2003,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 420,PHI:402,UniProt,Q99078,EMBL,AAA62242,,,FBD12,FUZ7,,,,,,,5270,Ustilago maydis,559306,FB1; FB2; SG200; HA1033,smut (corn),monocots,4577,Zea mays (related: maize),,,,,MAP kinase kinase,"GO:0009405, IMP",GO,possibly 2 pathways plant/fungal signals,loss of pathogenicity,yes,,,,,,,,,,,,,,,,gene disruption,,,MU,7926737,PubMed,10.1101/gad.8.12.1367,,,,Banuett and Herskowitz,1994,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 421,PHI:404,UniProt,Q9Y784,EMBL,AAD30436,,,4091-5-8,PTH11,,,,,,,318829,Magnaporthe oryzae,1274781,4091-5-8,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,membrane protein,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,yes,no,no,,wild type,wild type,,,,,,,,,,gene disruption,,,MU,10521529,PubMed,10.1105/tpc.11.10.2013,,,Identification by REMI. Appressoria formation was 10-15% of wild-type frequencies,DeZwann et al.,1999,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 422,PHI:405,UniProt,Q9C2Y4,EMBL,AAK07740,,,Guy11,PDE1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,tagged; aminophospholipid translocase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,MU,11549759,PubMed,10.1073/pnas.231491298,,,partial gene disruption and S. cerevisiae mutant complementation,Balhadere and Talbot,2001,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 423,PHI:406,UniProt,Q9UQY5,EMBL,AAF09452,,,,UBC3,,,,,,,5270,Ustilago maydis,,,smut (corn),monocots,4577,Zea mays (related: maize),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,wild type,sterile,wild type,,,,,,,,,gene disruption,,,MU,10564490,PubMed,no data found,,,,Mayorga and Gold,1999,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 424,PHI:407,UniProt,Q9Y7G8,EMBL,CAB40372,,,JH26,PBC1,,,,,,,76659,Pyrenopeziza brassicae,,,light leaf spot,eudicots,3708,Brassica napus (related: rape),,,,,cutinase,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,,,,,,,,,,,,,,gene disruption,,,TKB; MU; KHK; AC,12795380,PubMed,10.1094/MPMI.2003.16.6.545,,,,Li et al.,2003,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 425,PHI:409,UniProt,Q8J1Y3,EMBL,AAN41259,,,,BbCHIT1,,,,,,,176275,Beauveria bassiana,,,,aphids,27482,Aphididae (related: aphids),,,,,chitinase,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,altered gene expression / gene regulation: overexpression,,,TKB,15640210,PubMed,10.1128/AEM.71.1.363-370.2005,,,,Fang et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 426,PHI:410,UniProt,Q5IFQ6,EMBL,AAW56834,,,H99,SOD2,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,superoxide dismutase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,15643059,PubMed,10.1128/EC.4.1.46-54.2005,,,,Giles et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 427,PHI:411,UniProt,Q5SC91,EMBL,AAV54029,,,521,ROP1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2; SG200; HA232,smut (corn),monocots,4577,Zea mays (related: maize),,,,,transcription factor,,,,unaffected pathogenicity,no,no,no,no,,,,"mating, pheromone response and filamentation defects",,,,,,,,,gene deletion,,,TKB,15701800,PubMed,10.1128/EC.4.2.379-391.2005,,kahmann@staff.uni-marburg.de,,Brefort et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 428,PHI:412,UniProt,Q5J7N6,EMBL,AAS64313,,,,CHAP1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15701806,PubMed,10.1128/EC.4.2.443-454.2005,,Israel. horwitz@tx.technion.ac.il,Cochliobolus heterostrophus is pathogen anamorph name,Lev et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 429,PHI:413,UniProt,Q5GFD3,EMBL,AAT84078,,,,MPD1,,,,,,,13684,Parastagonospora nodorum,,,glume blotch,monocots,4564,Triticum (related: wheat),,,,,mannitol 1-phosphate dehydrogenase,GO:0008926,GO,,unaffected pathogenicity,,no,no,no,,absent (no sporulation),,,,,,,,,,,gene disruption,,RO,TKB; MU; KHK; AC,15720079,PubMed,10.1094/MPMI-18-0110,Solomon et al. (2005) Mol Plant Microbe Interact. 18 (2): 110-115,roliver@murdoch.edu.au,,Solomon et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 430,PHI:414,UniProt,Q696X2,EMBL,AAT73077,,,,GOX1,,,,,,,13684,Parastagonospora nodorum,,,glume blotch,monocots,4565,Triticum aestivum (related: bread wheat),,,,,glyoxalase,,,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption,,RO,TKB; MU; AC,15205912,PubMed,10.1007/s00294-004-0514-8,Solomon et al. (2004) Current Genetics 46(2);115-121,psolomon@murdoch.edu.au,,Solomon et al.,2004,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 431,PHI:415,UniProt,F5HCK8,Broad,SNOG_02041,,,,IPMDH,,,,,,,13684,Parastagonospora nodorum,,,glume blotch,monocots,4564,Triticum (related: wheat),,,,,3-isopropylmalate dehydrogenase,"GO:0003862; GO:0009405, IMP",GO,biosynthesis pathway to leucine,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,,Not in PubMed,10.1002/(SICI)1096-9063(199903)55:3<364::AID-PS910>3.0.CO;2-K,Cooley et al. 1999 PESTICIDE SCIENCE 55(3) 364-367,,,Cooley et al.,1999,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 432,PHI:416,UniProt,Q5D6D3,EMBL,AAX09988,,,,NPS6,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),,,,,non-ribosomal peptide synthetase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,15755917,PubMed,10.1128/EC.4.3.545-555.2005,,,Cochliobolus heterostrophus is pathogen anamorph name,Lee et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 433,PHI:416,UniProt,Q5D6D3,EMBL,AAX09988,,,,NPS6,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),,,,,non-ribosomal peptide synthetase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,AB,17056706,PubMed,10.1105/tpc.106.045633,,bgt1@cornell.edu,Complementation made using orthologue. Hypersensitivity to H2O2. Increased sensitivity to iron depletion. Cochliobolus heterostrophus is pathogen anamorph name,Oide et al.,2006,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 434,PHI:417,UniProt,G4NEB8,GenBank,EHA48601,,,,MST7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,MAP kinase kinase,"GO:0009405, IMP; GO:0044409, IMP; GO:0044412, IMP; GO:0048622, IMP",GO,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15749760,PubMed,10.1105/tpc.104.029116,,,,Zhao et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 435,PHI:418,UniProt,G4N7X0,GenBank,EHA50924,,,,MST11,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,MAP kinase kinase kinase,"GO:0009405, IMP; GO:0044409, IMP; GO:0044412, IMP; GO:0048622, IMP",GO,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15749760,PubMed,10.1105/tpc.104.029116,,,,Zhao et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 436,PHI:419,UniProt,Q7Z8E8,EMBL,AAP93915,,,R3b,CSH1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,cell surface protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15766793,PubMed,10.1016/j.femsle.2005.02.010,,,,Singleton et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 437,PHI:420,UniProt,Q6TDT0,EMBL,AAS19620,,,ATCC 32609; NIH 444,SOD2,,,,,,PHI:318,552467,Cryptococcus bacillisporus,,,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),,,,,superoxide dismutase,"GO:0009405, IGI",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; SH,15752200,PubMed,10.1111/j.1365-2958.2005.04503.x,,,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,Narasipura et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 438,PHI:420,UniProt,Q6TDT0,EMBL,AAS19620,,,ATCC 32609; NIH 444,SOD2,,,,,,,552467,Cryptococcus bacillisporus,,,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),,,,,superoxide dismutase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; SH,15752200,PubMed,10.1111/j.1365-2958.2005.04503.x,,,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,Narasipura et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 439,PHI:422,UniProt,Q9C402,EMBL,AAK01665,,,H99,SOD1,,,,,,PHI:668,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,superoxide dismutase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,14614821,PubMed,no data found,,,Tested in A/Jcr mice; Significantly more attenuated for virulence than the fhb1 and sod1 single mutants,de Jesus-Berrios et al,2003,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 440,PHI:422,UniProt,Q9C402,EMBL,AAK01665,,,H99,SOD1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,superoxide dismutase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; SH,14614821,PubMed,no data found,,,Tested in A/Jcr mice,de Jesus-Berrios et al,2003,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 441,PHI:422,UniProt,Q9C402,EMBL,AAK01665,,,H99,SOD1,,,,,,PHI:667,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,superoxide dismutase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,14614821,PubMed,no data found,,,Tested in A/Jcr mice; Significantly more attenuated for virulence than the fhb1 and sod1 single mutants,de Jesus-Berrios et al,2003,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 442,PHI:423,UniProt,Q58Z64,EMBL,AAV41010,,,,VAD1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,RNA helicase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,15765146,PubMed,10.1172/JCI200523048,,,,Panepinto et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 443,PHI:424,UniProt,F5HAA8,EMBL,EAL19243,,,B-3501A,PCK1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,phosphoenolpyruvate carboxykinase,"GO:0004612; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,15765146,PubMed,10.1172/JCI200523048,,,,Panepinto et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 444,PHI:425,UniProt,F5HEZ0,EMBL,EAL17726,,,B-3501A,MPF3,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,mannoprotein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,15765146,PubMed,10.1172/JCI200523048,,,,Panepinto et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 445,PHI:427,UniProt,Q5AP71,EMBL,EAL04880,,,SC5314,TPK1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,PKA catalytic subunit,,,Ras-protein kinase A,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15760450,PubMed,10.1111/j.1462-5822.2004.00476.x,,,,Park et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 446,PHI:428,UniProt,Q9P932,EMBL,AAF64072,,,strain 1161,TPK2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,PKA catalytic subunit,"GO:0009405, IMP",GO,Ras-protein kinase A,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15760450,PubMed,10.1111/j.1462-5822.2004.00476.x,,,,Park et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 447,PHI:429,UniProt,Q8J0E2,EMBL,CAD43407,,,UPS9,ClPLS1,,,,,,,290576,Colletotrichum lindemuthianum,,,anthracnose,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,tetraspanin,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,no,yes,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15749050,PubMed,10.1016/j.fgb.2005.01.009,,,,Veneault-Fourrey et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 448,PHI:430,UniProt,Q5EGQ2,EMBL,AAW72937,,,JEC21,BWC1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,UV/blue light response,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,15760278,PubMed,10.1371/journal.pbio.0030095,,,Interacts with BWC2,Idnurm and Heitman,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 449,PHI:431,UniProt,Q5EGQ1,EMBL,AAW72938,,,JEC21,BWC2,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor; zinc finger DNA binding domain; UV/blue light response,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion; gene complementation,,,TKB; KHK,15760278,PubMed,10.1371/journal.pbio.0030095,,,Interacts with BWC1,Idnurm and Heitman,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 450,PHI:432,UniProt,Q6WER3,EMBL,AAQ23181,,,,FGL1,,,,,,,5518,Fusarium graminearum,,8/1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),,,,,secreted lipase,"GO:0009405, IMP",GO,,reduced virulence,,no,,,,,,,,,,,,,,,gene disruption,,,TKB; AB; AC,15842622,PubMed,10.1111/j.1365-313X.2005.02377.x,Voigt et al. (2005) Plant Journal 42(3): 364-375,schaefer@botanik.uni-hamburg.de,,Voigt et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 451,PHI:432,UniProt,Q6WER3,EMBL,AAQ23181,,,,FGL1,,,,,,,5518,Fusarium graminearum,,8/1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,secreted lipase,"GO:0009405, IMP",GO,,reduced virulence,,no,,,,,,,,,,,,,,,gene disruption,,,TKB; AB; AC,15842622,PubMed,10.1111/j.1365-313X.2005.02377.x,Voigt et al. (2005) Plant Journal 42(3): 364-375,schaefer@botanik.uni-hamburg.de,,Voigt et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 452,PHI:433,UniProt,Q6DQW3,EMBL,AAT69682,,,,CTB1,,,,,,,29003,Cercospora nicotianae,,,,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,polyketide synthase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene disruption; gene deletion; gene complementation,,,TKB,15915645,PubMed,10.1094/MPMI-18-0468,,,CTB1 is required for cercosporin biosynthesis. Isolated from a library of REMI mutants,Choquer et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 453,PHI:434,UniProt,P0C954,EMBL,EAL88984,,,Af293,GEL2,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,"beta-1,3-glucanosyltransferase","GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15916615,PubMed,10.1111/j.1365-2958.2005.04654.x,,,,Mouyna et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 454,PHI:435,UniProt,Q5AHJ0,EMBL,EAL02110,,,SC5314,VMA7,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,H+-ATPase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15870472,PubMed,10.1099/mic.0.27505-0,,,,,,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 455,PHI:436,UniProt,Q8NJN5,EMBL,AAN03477,,,,ESS1,,,,,,,5207,Cryptococcus neoformans,,serotype D strain JEC43,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,peptidyl-prolyl cis/trans isomerases,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; KHK,15870468,PubMed,10.1099/mic.0.27786-0,,,,Ren et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 456,PHI:437,UniProt,P78608,EMBL,CAA71247,,,T5,CPPG2,,,,,,PHI:247,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,endopolygalacturonase,"GO:0009405, IGI; GO:0044412",GO,,loss of pathogenicity,,no,no,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU; AC,12135573,PubMed,10.1016/S1087-1845(02)00020-8,Oeser et al. (2002) Fungal Genetics and Biology 36(3): 176-186,tenberg@uni-muenster.de,,Oeser et al.,2002,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 457,PHI:438,UniProt,Q6WP49,EMBL,AAQ16576,,,T4,BcBOT1 (CND5),,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,cytochrome P450 monooxygenase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene deletion,,,TKB; MU,15986930,PubMed,10.1094/MPMI-18-0602,,,"Essential for botrydiol toxin synthesis, Reduced Virulence-strain specific",Siewers et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 458,PHI:438,UniProt,Q6WP49,EMBL,AAQ16576,,,T4,BcBOT1 (CND5),,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,cytochrome P450 monooxygenase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene deletion,,,TKB; MU,15986930,PubMed,10.1094/MPMI-18-0602,,,"Essential for botrydiol toxin synthesis, Reduced Virulence-strain specific",Siewers et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 459,PHI:439,UniProt,Q9UWE7,EMBL,BAA83722,,,PH-1; NRRL 31084,TRI6,,,,,,,5518,Fusarium graminearum,229533,R5317,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,,transcription factor,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,wild type,,,,,,,,,,,altered gene expression / gene regulation: silencing,,,TKB; AB; AC,15986923,PubMed,10.1094/MPMI-18-0539,McDonald et al. (2005) Mol Plant Microbe Interact 18 (6): 539-545,npk@plantpath.wisc.edu,,McDonald et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 460,PHI:440,UniProt,Q9P872,EMBL,CAB87245,,,,PMR1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,P-type ATPase transporter,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,15843378,PubMed,10.1074/jbc.M502162200,,,,Bates et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 461,PHI:441,UniProt,Q6A2T2,EMBL,CAE55153,,,SAS56,BTP1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3750,Malus domestica (related: apple),,,,,G-protein coupled receptor,,,,unaffected pathogenicity,,,,no,,,,,,,,,,,,,gene deletion,,,TKB; MU,20565654,PubMed,10.1111/j.1364-3703.2005.00278.x,Gronover et al. (2005) MOLECULAR PLANT PATHOLOGY 6(3). 243-256,,Expression of glutathione S transferases is affected in the BTP1 deletion mutant.,Gronover et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 462,PHI:441,UniProt,Q6A2T2,EMBL,CAE55153,,,SAS56,BTP1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,G-protein coupled receptor,,,,unaffected pathogenicity,,,,no,,,,,,,,,,,,,gene deletion,,,TKB; MU,20565654,PubMed,10.1111/j.1364-3703.2005.00278.x,Gronover et al. (2005) MOLECULAR PLANT PATHOLOGY 6(3). 243-256,,Expression of glutathione S transferases is affected in the BTP1 deletion mutant.,Gronover et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 463,PHI:441,UniProt,Q6A2T2,EMBL,CAE55153,,,SAS56,BTP1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,,G-protein coupled receptor,,,,unaffected pathogenicity,,,,no,,,,,,,,,,,,,gene deletion,,,TKB; MU,20565654,PubMed,10.1111/j.1364-3703.2005.00278.x,Gronover et al. (2005) MOLECULAR PLANT PATHOLOGY 6(3). 243-256,,Expression of glutathione S transferases is affected in the BTP1 deletion mutant.,Gronover et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 464,PHI:441,UniProt,Q6A2T2,EMBL,CAE55153,,,SAS56,BTP1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,G-protein coupled receptor,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,TKB; MU,20565654,PubMed,10.1111/j.1364-3703.2005.00278.x,Gronover et al. (2005) MOLECULAR PLANT PATHOLOGY 6(3). 243-256,,Expression of glutathione S transferases is affected in the BTP1 deletion mutant. Reduced virulence only with dilute inoculum.,Gronover et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 465,PHI:442,UniProt,I1S241,Broad,FGSG_10825,,,PH-1; NRRL 31084,MSY1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),,,,,methionine synthase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; AB; AC,18943005,PubMed,10.1094/PHYTO-95-0744,Seong et al. (2005) PHYTOPATHOLOGY 95(7) 744-750,,,Seong et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 466,PHI:442,UniProt,I1S241,Broad,FGSG_10825,,,PH-1; NRRL 31084,MSY1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,,methionine synthase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; AB; AC,18943005,PubMed,10.1094/PHYTO-95-0744,Seong et al. (2005) PHYTOPATHOLOGY 95(7) 744-750,,,Seong et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 467,PHI:443,UniProt,I1RE58,Broad,FG01932,,,PH-1; NRRL 31084,CBL1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,,cystathionine beta-lyase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; AB; MU; AC,18943005,PubMed,10.1094/PHYTO-95-0744,Seong et al. (2005) PHYTOPATHOLOGY. 95(7) 744-750,,,Seong et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 468,PHI:443,UniProt,I1RE58,Broad,FG01932,,,PH-1; NRRL 31084,CBL1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),,,,,cystathionine beta-lyase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; AB; MU; AC,18943005,PubMed,10.1094/PHYTO-95-0744,Seong et al. (2005) PHYTOPATHOLOGY. 95(7) 744-750,,,Seong et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 469,PHI:444,UniProt,I1RD66,Broad,FG01555,,,PH-1; NRRL 31084,ZIF1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),,,,,b-ZIP transcription factor,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene disruption,,,TKB; AB; MU; AC,18943005,PubMed,10.1094/PHYTO-95-0744,Seong et al. (2005) PHYTOPATHOLOGY. 95(7) 744-750,,,Seong et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 470,PHI:444,UniProt,I1RD66,Broad,FG01555,,,PH-1; NRRL 31084,ZIF1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,,b-ZIP transcription factor,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene disruption,,,TKB; AB; MU; AC,18943005,PubMed,10.1094/PHYTO-95-0744,Seong et al. (2005) PHYTOPATHOLOGY. 95(7) 744-750,,,Seong et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 471,PHI:445,UniProt,I1RA52,Broad,FG00376,,,PH-1; NRRL 31084,NOS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,,ubiquinone oxidoreductase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene disruption,,,TKB; AB; MU; AC,18943005,PubMed,10.1094/PHYTO-95-0744,Seong et al. (2005) PHYTOPATHOLOGY 95(7) 744-750,,,Seong et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 472,PHI:445,UniProt,I1RA52,Broad,FG00376,,,PH-1; NRRL 31084,NOS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),,,,,ubiquinone oxidoreductase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene disruption,,,TKB; AB; MU; AC,18943005,PubMed,10.1094/PHYTO-95-0744,Seong et al. (2005) PHYTOPATHOLOGY 95(7) 744-750,,,Seong et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 473,PHI:446,UniProt,A0A1C3YHH5,EMBL,FGRAMPH1_01T00873,,,PH-1; NRRL 31084,TBL1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),,,,,transducin beta-subunit,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene disruption,,,TKB; AB; MU; AC,18943005,PubMed,10.1094/PHYTO-95-0744,Seong et al. (2005) PHYTOPATHOLOGY 95(7) 744-750,,,Seong et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 474,PHI:446,UniProt,A0A1C3YHH5,EMBL,FGRAMPH1_01T00873,,,PH-1; NRRL 31084,TBL1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,,transducin beta-subunit,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene disruption,,,TKB; AB; MU; AC,18943005,PubMed,10.1094/PHYTO-95-0744,Seong et al. (2005) PHYTOPATHOLOGY 95(7) 744-750,,,Seong et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 475,PHI:2348,UniProt,A0A1C3YHH5,EMBL,FGRAMPH1_01T00873,,,PH-1,FTL1 (TBL1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,transducin-beta-like gene acting as a component of the Set3 complex involved in late stages of ascospore formation,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: partial,,MU,MU,19377037,PubMed,10.1128/EC.00048-09,,jinrong@purdue.edu,update of PHI:446,Ding,2009,,,,2006-05-04,MU,"Xu, X. R.",,,,,,,,,,,,
,,Record 476,PHI:447,,no data found,EMBL,CAI48090,,,ATCC 46645,MCSA,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,methylcitrate synthase,"GO:0009405, IMP; GO:0050440",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; MU,16008561,PubMed,10.1111/j.1742-4658.2005.04784.x,,,,,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 477,PHI:448,UniProt,F5HEA9,Broad,SNOG_03299,,,,MAK2,,,,,,,13684,Parastagonospora nodorum,,,glume blotch,monocots,4564,Triticum (related: wheat),,,,,MAP kinase,"GO:0009405, IMP; GO:0044409; GO:0044412",GO,,loss of pathogenicity,,yes,yes,yes,,absent (no sporulation),,"reduced by 20% on solid media, 30% in liquid culture",,,,,,,,,gene disruption,,RO,TKB; AC,16028107,PubMed,10.1007/s00294-005-0588-y,Solomon et al. (2005) Current Genetics 48(1): 60-68,psolomon@murdoch.edu.au,PMK1 homologue. Transposon mutagenesis,Solomon et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 478,PHI:449,UniProt,Q2PBY8,EMBL,CAI48090,,,T5,CDC42,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,GTPase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU; AC,16002649,PubMed,10.1128/EC.4.7.1228-1238.2005,Scheffer et al.(2005) Eukaryotic Cell 4(7): 1228-1238,tudzyns@uni-muenster.de,,Scheffer et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 479,PHI:450,UniProt,Q5UB48,EMBL,AAV36564,,,H99,SKN7,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,16041017,PubMed,10.1128/IAI.73.8.5022-5030.2005,,,More susceptible to reactive oxygen species in vitro and floccates in liquid culture.,Wormley et al.,2005,,,PHI-base Vers.3.3,2006-05-04,RRes,,,,,,,,,,,,,
,,Record 480,PHI:451,UniProt,O74189,EMBL,AAC31119,,,CAF3-1,PMT1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,mannosyltransferase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,9694829,PubMed,10.1074/jbc.273.33.20837,,,,Timpel et al.,1998,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 481,PHI:452,UniProt,Q9UVB5,EMBL,AAF16867,,,1006,PMT6,,,,,,,5476,Candida albicans,5477,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,mannosyltransferase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10809683,PubMed,10.1128/jb.182.11.3063-3071.2000,,,,Timpel et al.,2000,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 482,PHI:453,UniProt,Q5ACU3,EMBL,EAL00423,,,SC5314,PMT5,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,mannosyltransferase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,16040968,PubMed,10.1128/IAI.73.8.4571-4580.2005,,,Haematogenously disseminated candidiasis,Rouabhia et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 483,PHI:453,UniProt,Q5ACU3,EMBL,EAL00423,,,SC5314,PMT5,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,mannosyltransferase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB,15659169,PubMed,10.1111/j.1365-2958.2004.04401.x,,,Haematogenously disseminated candidiasis,Prill et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 484,PHI:453,UniProt,Q5ACU3,EMBL,EAL00423,,,SC5314,PMT5,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,primates,9606,Homo sapiens (related: human),,,,,mannosyltransferase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,16040968,PubMed,10.1128/IAI.73.8.4571-4580.2005,,,Engineered human oral mucosa,Rouabhia et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 485,PHI:454,UniProt,Q5ADM9,EMBL,EAL01044,,,SC5314,PMT2,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,mannosyltransferase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,16040968,PubMed,10.1128/IAI.73.8.4571-4580.2005,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 486,PHI:455,UniProt,Q00523,EMBL,AAC13946,,,,CAP59,,,,,,,5207,Cryptococcus neoformans,,B-3501,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,capsule formation,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene deletion; gene complementation,,,TKB; KHK,8007987,PubMed,10.1128/mcb.14.7.4912,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 487,PHI:455,UniProt,Q00523,EMBL,AAC13946,,,,CAP59,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion; gene complementation,,AI,SH; KHK,15972469,PubMed,10.1128/IAI.73.7.3842-3850.2005,,,Tested in G.mellonella caterpillars in the final instar larval stage,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 488,PHI:455,UniProt,Q00523,EMBL,AAC13946,,,,CAP59,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion; gene complementation,,AI,SH; KHK,15075271,PubMed,10.1128/EC.3.2.413-419.2004,,,Tested in Oregon-R flies,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 489,PHI:455,UniProt,Q00523,EMBL,AAC13946,,,,CAP59,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion; gene complementation,,AI,SH; KHK,12438649,PubMed,10.1073/pnas.232568599,,,Tested in C.elegans strain N2 Bristol,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 490,PHI:457,UniProt,Q5A409,EMBL,EAK97437,,,SC5314,CHS2,,,,,,,5476,Candida albicans,5476,SGY243,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,chitin synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB,8016141,PubMed,10.1073/pnas.91.13.6216,,,,Gow et al,1994,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 491,PHI:458,UniProt,O94196,EMBL,AAD18059,,,70-15,MHP1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hydrophobin,"GO:0009405, IMP; GO:0044412, IMP; GO:0009847, IMP; GO:0030437, IMP",GO,,reduced virulence,,yes,no,yes,,reduced,,wild type,reduced,,,,,,,,gene disruption; gene complementation,,,TKB; MU,16101997,PubMed,10.1111/j.1365-2958.2005.04750.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 492,PHI:459,UniProt,Q99067,EMBL,CAA79218,,,"Uh112 (MAT-1, ade)",UhbE1,,,,,,PHI:460,120017,Ustilago hordei,,,smut (barley),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,mating locus protein,"GO:0009405, IGI",GO,,loss of pathogenicity,no,,,,,,,,,,,,,,,,gene disruption,,,TKB,8844149,PubMed,no data found,,,"Also disrupted in the MAT-2 strain, with the same pathogenicity defect.",Bakkeren et al.,1996,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 493,PHI:460,UniProt,Q99071,EMBL,CAA79219,,,"Uh112 (MAT-1, ade)",UhbW1,,,,,,PHI:459,120017,Ustilago hordei,,,smut (barley),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,mating locus protein,"GO:0009405, IGI",GO,,loss of pathogenicity,no,,,,,,,,,,,,,,,,gene disruption,,,TKB,8844149,PubMed,no data found,,,"Also disrupted in the MAT-2 strain, with the same pathogenicity defect.",Bakkeren et al.,1996,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 494,PHI:461,UniProt,P0CY23,EMBL,AAB38875,,,1066,CST20,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,8917571,PubMed,10.1073/pnas.93.23.13217,,,STE20 homologue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 495,PHI:462,UniProt,C4YLK8,EMBL,AAB59338,,,WO1,HST7,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,8917571,PubMed,10.1073/pnas.93.23.13217,,,STE7 homologue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 496,PHI:463,UniProt,P02829,EMBL,AAA02743,,,,HSP90,,,,,,,4932,Saccharomyces cerevisiae,,,,rodents,10090,Mus musculus (related: house mouse),,,,,heat shock protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,altered gene expression / gene regulation: overexpression,,,TKB; MU,9116640,PubMed,10.1111/j.1574-695X.1996.tb00140.x,,,knockout is lethal,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 497,PHI:464,UniProt,P87198,EMBL,AAB63336,,,,KIN1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,kinesin,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9218789,PubMed,10.1093/emboj/16.12.3464,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 498,PHI:465,UniProt,P87199,EMBL,AAB63337,,,,KIN2,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,kinesin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,9218789,PubMed,10.1093/emboj/16.12.3464,,,Post-mating defect,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 499,PHI:466,UniProt,P49605,EMBL,AAA57470,,,518,UBC1,,,,,,,5270,Ustilago maydis,,,smut (corn),monocots,4577,Zea mays (related: maize),,,,,PKA regulatory subunit,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene disruption,,,TKB,9338961,PubMed,10.1105/tpc.9.9.1585,,,,Gold et al.,1997,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 500,PHI:467,UniProt,P87090,EMBL,AAC16255,,,EP155,CPC1,,,,,,,5116,Cryphonectria parasitica,,,blight (chestnut),eudicots,134033,Castanea dentata (related: american chestnut),,,,,general amino acid control transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene mutation,,,TKB; MU,9501479,PubMed,10.1006/fgbi.1997.1023,,,Constitutive transgenic expression of a DNA binding defective CPC1 led to reduced virulence.,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 501,PHI:468,UniProt,Q6VBJ0,EMBL,AAQ82691,,,,EPA1,,,,,,,5478,Candida glabrata,,,candidiasis,primates,9606,Homo sapiens (related: human),,,,,cell wall protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; MU,10417386,PubMed,10.1126/science.285.5427.578,,,Reduced adhesion to human epithelial cells,Cormack et al,1999,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 502,PHI:469,UniProt,Q9UW18,EMBL,AAD47837,,,SB111,TOXG,,,,,,,5017,Bipolaris zeicola,,164R10,leaf spot,monocots,4577,Zea mays (related: maize),,,,,alanine racemase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; JA,10671527,PubMed,10.1074/jbc.275.7.4906,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 503,PHI:470,UniProt,O42722,EMBL,AAC01955,,,JEC21,STE12alpha,,,,,,,5207,Cryptococcus neoformans,214684,serotype D strain B4500; serotype D strain JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,10704467,PubMed,10.1084/jem.191.5.871,,,Serotype D,Chang et al,2000,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 504,PHI:471,UniProt,C4YDI6,EMBL,AAB69764,,,WO1,CDC42,,,,,,,5476,Candida albicans,5476,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,polarity establishment protein,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12582118,PubMed,10.1128/EC.2.1.9-18.2003,,,GTPase,Bassilana et al.,2003,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 505,PHI:472,UniProt,Q8NID8,EMBL,CAD16675,,,race 4,AVR2,,,,,,,5499,Fulvia fulva,,,leaf mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene mutation,,,TKB; MU,15845874,PubMed,10.1126/science.1111404,,,,Rooney et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 506,PHI:473,UniProt,Q572D3,EMBL,CAI72345,,,,AVR3a,,,,,,,4787,Phytophthora infestans,,,late blight,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,other evidence,,,TKB; MU,15894622,PubMed,10.1073/pnas.0500113102,,,Coexpression of Avr3a and R3a in N. benthamiana results in host cell death,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 507,PHI:474,UniProt,P0CM54,EMBL,AAG13937,,,,CNB1,,,,,,,5207,Cryptococcus neoformans,214684,serotype D strain JEC20; serotype D strain JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,calcineurin B regulatory subunit,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11251806,PubMed,no data found,,,Serotype D,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 508,PHI:475,UniProt,Q9C1I3,EMBL,AAK15315,,,,RFG1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription regulator,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB,11259598,PubMed,10.1128/MCB.21.7.2496-2505.2001,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 509,PHI:476,UniProt,Q9HFT9,EMBL,AAG30205,,,,STE11alpha,,,,,,,5207,Cryptococcus neoformans,,WSA-7,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,MAP kinase kinase kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,11298287,PubMed,no data found,,,Serotype D minor reduction in virulence,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 510,PHI:477,UniProt,Q59RB8,EMBL,EAK93039,,,SC5314,ICL1,,,,,,,5476,Candida albicans,,,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,isocitrate lyase,"GO:0009405, IMP",GO,glyoxylate cycle,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; MU,11452311,PubMed,10.1038/35083594,,,key paper,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 511,PHI:478,UniProt,Q8X1S9,EMBL,AAL55095,,,521,HGL1,,,,,,,5270,Ustilago maydis,237631,518; 521,smut (corn),monocots,4577,Zea mays (related: maize),,,,,transcription regulator,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB,11489122,PubMed,no data found,,,No teliospore production by the hgl1 mutant in planta,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 512,PHI:479,UniProt,C5P3X6,EMBL,AAQ07436,,,C735,MEP1,,,,,,,199306,Coccidioides posadasii,199306,C735,respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,,metalloproteinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; JA,16177346,PubMed,10.1128/IAI.73.10.6689-6703.2005,,,SOWgp-immune mice challenged with the MEP1 mutant show increased survival,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 513,PHI:480,UniProt,Q59VH7,EMBL,EAK94461,,,SC5314,SAP7,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,aspartyl proteinase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,16177393,PubMed,10.1128/IAI.73.10.7061-7063.2005,,,Vaginal infection,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 514,PHI:480,UniProt,Q59VH7,EMBL,EAK94461,,,SC5314,SAP7,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,aspartyl proteinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,16177393,PubMed,10.1128/IAI.73.10.7061-7063.2005,,,Intravenous infection,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 515,PHI:481,UniProt,Q5D1P9,EMBL,AAX14039,,,,KLAP1,,,,,,,27357,Colletotrichum acutatum,,,anthracnose,eudicots,159033,Citrus x aurantiifolia (related: lime),,,,,transcription activator,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; MU,20565676,PubMed,10.1111/J.1364-3703.2005.00300.X,Chen et al. (2005) MOLECULAR PLANT PATHOLOGY. 6(5) 513-525,,Key lime flowers,,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 516,PHI:481,UniProt,Q5D1P9,EMBL,AAX14039,,,,KLAP1,,,,,,,27357,Colletotrichum acutatum,,,anthracnose,eudicots,159033,Citrus x aurantiifolia (related: lime),,,,,transcription activator,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,no,yes,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; MU,20565676,PubMed,10.1111/J.1364-3703.2005.00300.X,Chen et al. (2005) MOLECULAR PLANT PATHOLOGY. 6(5) 513-525,,Key lime leaves,,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 517,PHI:482,UniProt,Q6TFC7,EMBL,AAR01218,,,,LAEA,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription regulator,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,16151250,PubMed,10.1128/EC.4.9.1574-1582.2005,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 518,PHI:483,UniProt,Q5EKM7,EMBL,AAW71477,,,,VMK1,,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,4073,Capsicum frutescens (related: hot pepper),,,,,MAP kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,reduced,,,,,,,,,,,gene disruption,,,TKB,16003535,PubMed,10.1007/s00294-005-0586-0,,,Agrobacterium transformation. FUS3/KSS1 homologue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 519,PHI:483,UniProt,Q5EKM7,EMBL,AAW71477,,,,VMK1,,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced,,,,,,,,,,,gene disruption,,,TKB,16003535,PubMed,10.1007/s00294-005-0586-0,,,Agrobacterium transformation. FUS3/KSS1 homologue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 520,PHI:483,UniProt,Q5EKM7,EMBL,AAW71477,,,,VMK1,,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced,,,,,,,,,,,gene disruption,,,TKB,16003535,PubMed,10.1007/s00294-005-0586-0,,,Agrobacterium transformation. FUS3/KSS1 homologue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 521,PHI:483,UniProt,Q5EKM7,EMBL,AAW71477,,,,VMK1,,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,3654,Citrullus lanatus (related: wild melon),subsp. vulgaris,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced,,,,,,,,,,,gene disruption,,,TKB,16003535,PubMed,10.1007/s00294-005-0586-0,,,Agrobacterium transformation. FUS3/KSS1 homologue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 522,PHI:483,UniProt,Q5EKM7,EMBL,AAW71477,,,,VMK1,,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,4265,Cynara cardunculus (related: wild artichoke),var. scolymus (globe artichoke),,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced,,,,,,,,,,,gene deletion,,,TKB; MU,16003535,PubMed,10.1007/s00294-005-0586-0,,,Agrobacterium transformation. FUS3/KSS1 homologue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 523,PHI:483,UniProt,Q5EKM7,EMBL,AAW71477,,,,VMK1,,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced,,,,,,,,,,,gene disruption,,,TKB,16003535,PubMed,10.1007/s00294-005-0586-0,,,Agrobacterium transformation. FUS3/KSS1 homologue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 524,PHI:483,UniProt,Q5EKM7,EMBL,AAW71477,,,,VMK1,,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced,,,,,,,,,,,gene disruption,,,TKB,16003535,PubMed,10.1007/s00294-005-0586-0,,,Agrobacterium transformation. FUS3/KSS1 homologue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 525,PHI:484,UniProt,Q5AA40,EMBL,EAK99541,,,SC5314,CHS7,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,chitin synthesis,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,16079341,PubMed,10.1099/mic.0.28093-0,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 526,PHI:485,UniProt,Q9P8U9,EMBL,AAF69680,,,,FTR1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,high affinity iron permease,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,10807578,PubMed,10.1126/science.288.5468.1062,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 527,PHI:486,UniProt,E9QYP0,EMBL,AAX40989,,,,SIDA,,,,,,,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,L-ornithine N5-oxygenase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,16113265,PubMed,10.1128/IAI.73.9.5493-5503.2005,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 528,PHI:488,UniProt,Q59SR6,EMBL,EAK93583,,,SC5314,IRS4,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,negative regulator of MAP kinase pathway,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,16151204,PubMed,10.1099/mic.0.27998-0,,,Intravenously disseminated candidiasis,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 529,PHI:489,UniProt,Q5K8C9,EMBL,AAW46720,,,JEC21,TRX1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,thioredoxin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,reduced,,,,,,,,,gene deletion,,,TKB; SH,16045626,PubMed,10.1111/j.1365-2958.2005.04735.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 530,PHI:489,UniProt,Q5K8C9,EMBL,AAW46720,,,JEC21,TRX1,,,,,,PHI:575,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,thioredoxin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,reduced,,,,,,,,,gene deletion,,,SH; KHK,16045626,PubMed,10.1111/j.1365-2958.2005.04735.x,,,double mutant results in greater reduced virulence than wildtype and TRX1 mutant,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 531,PHI:490,UniProt,Q6B957,EMBL,AAT85969,,,,FRP1,,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici race 2 strain Fol007,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,F-box protein,"GO:0009405, IMP; GO:0044409, IMP; GO:0009847, IMP",GO,,loss of pathogenicity,,yes,yes,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; AB,16091043,PubMed,10.1111/j.1365-2958.2005.04751.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 532,PHI:491,UniProt,Q59ZY7,EMBL,EAK96144,,,SC5314,YVH1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,phosphatase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,16000712,PubMed,10.1099/mic.0.27999-0,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 533,PHI:492,UniProt,Q4G495,EMBL,AAV84614,,,B05.10,BcPG2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,endopolygalacturonase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,TKB,15998308,PubMed,10.1111/j.1365-313X.2005.02436.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 534,PHI:492,UniProt,Q4G495,EMBL,AAV84614,,,B05.10,BcPG2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,endopolygalacturonase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,TKB,15998308,PubMed,10.1111/j.1365-313X.2005.02436.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 535,PHI:493,UniProt,F2Z6H2,EMBL,AAT98628,,,,STE11,,,,,,,5478,Candida glabrata,,,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,MAP kinase kinase kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB,16110782,PubMed,10.1080/13693780400006088,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 536,PHI:494,UniProt,Q4WPX2,EMBL,EAL89712,,,Af293,PPOA,,,,,,PHI:495; PHI:496,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,fatty acid oxygenase,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,altered gene expression / gene regulation: silencing,,,TKB,16040966,PubMed,10.1128/IAI.73.8.4548-4559.2005,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 537,PHI:495,UniProt,E9NYS9,EMBL,ADW65671,,,,PPOB,,,,,,PHI:494; PHI:496,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,fatty acid oxygenase,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,altered gene expression / gene regulation: silencing,,,TKB,16040966,PubMed,10.1128/IAI.73.8.4548-4559.2005,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 538,PHI:496,UniProt,Q4WY82,EMBL,EAL92371,,,Af293,PPOC,,,,,,PHI:494; PHI:495,746128,Aspergillus fumigatus,,,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,fatty acid oxygenase,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,altered gene expression / gene regulation: silencing,,,TKB,16040966,PubMed,10.1128/IAI.73.8.4548-4559.2005,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 539,PHI:497,UniProt,Q56R42,EMBL,AAX08139,,,H99,HOG1,,,,,,,5207,Cryptococcus neoformans,235443,serotype A strain H99; serotype A strain KN99; serotype D strain JEC20; serotype D strain JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,MAP kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,15728721,PubMed,10.1091/mbc.E04-11-0987,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 540,PHI:498,,no data found,,,,,,PBS2,,,,,,,5207,Cryptococcus neoformans,235443,serotype A strain H99; serotype A strain KN99; serotype D strain JEC20; serotype D strain JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,MAP kinase kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,15728721,PubMed,10.1091/mbc.E04-11-0987,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 541,PHI:499,UniProt,Q5BUB4,EMBL,AAX19188,,,2.16,PiBZP1,,,,,,,4787,Phytophthora infestans,,,late blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,b-ZIP transcription factor,"GO:0009405, IMP; GO:0044409, IMP; GO:0050879, IMP",GO,,reduced virulence,,yes,yes,no,,,,,,,,,,,,,altered gene expression / gene regulation: silencing,,,TKB; KHK,15819621,PubMed,10.1111/j.1365-2958.2005.04575.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 542,PHI:500,UniProt,Q59MV9,EMBL,EAK91807,,,SC5314,YHB1,,,,,,,5476,Candida albicans,5476,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,NO-scavenging flavohemoglobin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB,15189992,PubMed,10.1128/EC.3.3.715-723.2004,,,,Ullmann et al,2004,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 543,PHI:501,UniProt,P21264,EMBL,CAA99327,,,,ADE2,,,,,,,4932,Saccharomyces cerevisiae,,,,rodents,10090,Mus musculus (related: house mouse),,,,,phosphoribosylaminoimidazole carboxylase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; KHK,11606528,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 544,PHI:502,UniProt,P04046,EMBL,CAA89133,,,AB972,ADE4,,,,,,,4932,Saccharomyces cerevisiae,,,,rodents,10090,Mus musculus (related: house mouse),,,,,amidophosphoribosyltransferase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; KHK,11606528,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 545,PHI:503,UniProt,P40086,EMBL,AAB64668,,,S288c (AB972),COX15,,,,,,,4932,Saccharomyces cerevisiae,,,,rodents,10090,Mus musculus (related: house mouse),,,,,cytochrome c oxidase assembly,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; KHK,11606528,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 546,PHI:504,UniProt,P04173,EMBL,CAA42366,,,S288C,LEU2,,,,,,,4932,Saccharomyces cerevisiae,,,,rodents,10090,Mus musculus (related: house mouse),,,,,beta-isopropyl-malate dehydrogenase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; KHK,11606528,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 547,PHI:505,UniProt,P15801,EMBL,AAA17543,,,,MIP1,,,,,,,4932,Saccharomyces cerevisiae,,,,rodents,10090,Mus musculus (related: house mouse),,,,,mitochondrial-specific DNA polymerase catalytic subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; KHK,11606528,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 548,PHI:506,UniProt,P03962,EMBL,AAA34824,,,,URA3,,,,,,,4932,Saccharomyces cerevisiae,,,,rodents,10090,Mus musculus (related: house mouse),,,,,orotidine 5'-phosphate decarboxylase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,TKB; KHK,11606528,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 549,PHI:507,UniProt,C4YKT4,EMBL,AAF03566,,,wo1,CaRAS1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,GTPase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,11722734,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 550,PHI:508,UniProt,Q96VB5,EMBL,BAB69076,,,NAF8,AFT1,,,,,,,5599,Alternaria alternata,,,black spot,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,,AF-toxin biosynthesis,"GO:0009405, IMP; GO:0044412",GO,,loss of pathogenicity,,,,yes,,,,,,,,,,,,,other evidence,,,TKB; KHK,12019223,PubMed,no data found,,,"Loss of AK-toxin production, loss of 1.05 Mb conditional dispensable chromosome",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 551,PHI:508,UniProt,Q96VB5,EMBL,BAB69076,,,NAF8,AFT1,,,,,,,5599,Alternaria alternata,,,black spot,eudicots,23211,Pyrus communis (related: pear),,,,,AF-toxin biosynthesis,"GO:0009405, IMP; GO:0044412",GO,,loss of pathogenicity,,,,yes,,,,,,,,,,,,,other evidence,,,TKB; KHK,12019223,PubMed,no data found,,,"Loss of AK-toxin production, loss of 1.05 Mb conditional dispensable chromosome",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 552,PHI:509,UniProt,Q96VB3,EMBL,BAB69078,,,NAF8,AFT3,,,,,,,5599,Alternaria alternata,,,black spot,eudicots,23211,Pyrus communis (related: pear),,,,,AF-toxin biosynthesis,"GO:0009405, IMP; GO:0044412",GO,,loss of pathogenicity,,,,yes,,,,,,,,,,,,,other evidence,,,TKB; KHK,12019223,PubMed,no data found,,,"Loss of AK-toxin production, loss of 1.05 Mb conditional dispensable chromosome",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 553,PHI:509,UniProt,Q96VB3,EMBL,BAB69078,,,NAF8,AFT3,,,,,,,5599,Alternaria alternata,,,black spot,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,,AF-toxin biosynthesis,"GO:0009405, IMP; GO:0044412",GO,,loss of pathogenicity,,,,yes,,,,,,,,,,,,,other evidence,,,TKB; KHK,12019223,PubMed,no data found,,,"Loss of AK-toxin production, loss of 1.05 Mb conditional dispensable chromosome",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 554,PHI:510,UniProt,Q59RG1,EMBL,EAK93097,,,SC5314,CaNAG3,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,,TKB,12076781,PubMed,10.1111/j.1574-6968.2002.tb11238.x,,,UV mutation,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 555,PHI:511,UniProt,Q59RG0,EMBL,EAK93098,,,SC5314,CaNAG4,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12076781,PubMed,10.1111/j.1574-6968.2002.tb11238.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 556,PHI:512,UniProt,Q9C0L9,EMBL,BAB43823,,,,CaNAG6,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,12076781,PubMed,10.1111/j.1574-6968.2002.tb11238.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 557,PHI:513,UniProt,Q5A2T6,EMBL,EAK97011,,,SC5314,ARN1 (SIT1),,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,siderophore transporter,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12183576,PubMed,10.1128/IAI.70.9.5246-5255.2002,,,Mouse model of systemic infection,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 558,PHI:513,UniProt,Q5A2T6,EMBL,EAK97011,,,SC5314,ARN1 (SIT1),,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,primates,9606,Homo sapiens (related: human),,,,,siderophore transporter,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,12183576,PubMed,10.1128/IAI.70.9.5246-5255.2002,,,Reconstituted human epithelium,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 559,PHI:514,UniProt,Q5AJ77,EMBL,EAL03004,,,SC5314,IRO1,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,16237272,PubMed,no data found,,,Putative transcription factor involved in iron utilisation. Adjacent to the URA3 gene,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 560,PHI:515,UniProt,Q8NJW8,EMBL,AAL93208,,,518,UKB1,,,,,,,5270,Ustilago maydis,237631,518; 521,smut (corn),monocots,4577,Zea mays (related: maize),,,,,serine/threonine kinase,"GO:0009405, IMP; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,,,,,,,,,,gene disruption,,,TKB,12223194,PubMed,no data found,,,Unable to form tumours,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 561,PHI:516,UniProt,Q9HG20,EMBL,AAG09422,,,H99,APP1,,,,,,,5207,Cryptococcus neoformans,,M001,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,secreted protein. anti-phagocytic.,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,14523045,PubMed,10.1172/JCI200318309,Luberto et al 2003,,Mice deficient for T and NK cells (Tgepsilon26),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 562,PHI:516,UniProt,Q9HG20,EMBL,AAG09422,,,H99,APP1,,,,,,,5207,Cryptococcus neoformans,,M001,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,secreted protein. anti-phagocytic.,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB; KHK,14523045,PubMed,10.1172/JCI200318309,Luberto et al 2003,,Mice deficient for complement C5 (A/Jcr),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 563,PHI:517,UniProt,G1UBC2,EMBL,EAK95520,,,SC5314,CaEAP1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,primates,9606,Homo sapiens (related: human),,,,,cell wall adhesin,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,14665461,PubMed,10.1128/EC.2.6.1266-1273.2003,,,Human kidney epithelial cell culture,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 564,PHI:518,UniProt,Q7Z8E9,EMBL,AAP93639,,,Guy11,MST20,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,PAK kinase,"GO:0030437, IMP; GO:0004672, NAS",GO,,unaffected pathogenicity,,no,no,no,,reduced,,wild type growth rate,,,,,,,,,gene deletion,,,TKB; MU,15141959,PubMed,10.1094/MPMI.2004.17.5.547,,,Partial gene deletion,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 565,PHI:519,UniProt,Q96UH9,EMBL,AAL15449,,,Guy11,CHM1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,PAK kinase,"GO:0004672, NAS; GO:0009405, IMP; GO:0044409, IMP; GO:0030437, IMP",GO,,reduced virulence,,yes,yes,no,,reduced,,reduced,,,,,,,,,gene deletion; gene complementation,,,TKB; MU,15141959,PubMed,10.1094/MPMI.2004.17.5.547,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 566,PHI:520,UniProt,Q5A755,EMBL,EAK98681,,,SC5314,NOT5,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription regulator,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB,16239513,PubMed,10.1128/IAI.73.11.7190-7197.2005,,,Reduced virulence phenotype depends on the infection method used.,Cheng et al,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 567,PHI:521,UniProt,O43117,EMBL,AAB92223,,,UQ62,CgDN24,,,,,,,474922,Colletotrichum gloeosporioides,,UQ62,anthracnose,eudicots,62615,Stylosanthes guianensis (related: stylo),,,,,unknown,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB; KHK,16255144,PubMed,10.1016/j.micres.2005.03.003,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 568,PHI:522,UniProt,Q2KN79,EMBL,AAX78216,,,,GAS1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,"beta-1,3-glucanosyltransferase","GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; AB,16353549,PubMed,10.1094/MPMI-18-1140,Caracuel et al. (2005) MOLECULAR PLANT-MICROBE INTERACTIONS. 18(11) 1140-1147,,Fruit infection,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 569,PHI:522,UniProt,Q2KN79,EMBL,AAX78216,,,,GAS1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,"beta-1,3-glucanosyltransferase","GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,TKB; AB,16353549,PubMed,10.1094/MPMI-18-1140,Caracuel et al. (2005) MOLECULAR PLANT-MICROBE INTERACTIONS. 18(11) 1140-1147,,Root infection,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 570,PHI:523,UniProt,G1UAU2,EMBL,AAQ03244,,,,FLO8,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,TKB,16267276,PubMed,10.1091/mbc.E05-06-0502,,,Homozygous disruption.,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 571,PHI:524,UniProt,Q4U320,EMBL,AAY42143,,,,CLN1,,,,,,,5270,Ustilago maydis,,FBD11,smut (corn),monocots,4577,Zea mays (related: maize),,,,,G1 cyclin,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; altered gene expression / gene regulation: overexpression,,,TKB,16258033,PubMed,10.1105/tpc.105.036319,,,Solo-pathogenic strain is fully pathogenic,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 572,PHI:524,UniProt,Q4U320,EMBL,AAY42143,,,,CLN1,,,,,,,5270,Ustilago maydis,,FBD11,smut (corn),monocots,4577,Zea mays (related: maize),,,,,G1 cyclin,"GO:0009405, IMP",GO,,loss of pathogenicity,yes,,,,,,,,,,,,,,,,gene disruption; altered gene expression / gene regulation: overexpression,,,TKB,16258033,PubMed,10.1105/tpc.105.036319,,,Haploid mutants unable to cause disease,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 573,PHI:525,,no data found,GenBank,EAA72509,,,PH-1; NRRL 31084,TRI14,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,,DON toxin biosynthesis,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,TKB; AB; AC,16277434,PubMed,10.1021/jf051441a,Dyer et al. (2005) J Agric Food Chem 53(23): 9281-9287,,In planta toxin production is abolished in the mutant.,Dyer et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 574,PHI:526,UniProt,Q705V7,EMBL,CAF05793,,,CL13,GAS1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,glucosidase 1,"GO:0009405, IMP; GO:0044412; GO:0004558",GO,,reduced virulence,no,no,no,yes,,,,,,,,,,,,indications that gas1 mutants provoke a plant response,gene deletion,,,TKB,16272431,PubMed,10.1105/tpc.105.036285,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 575,PHI:527,UniProt,Q59L12,EMBL,AAO72959,,,SC5314,ALS3,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,primates,9606,Homo sapiens (related: human),,,,,cell surface protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15256583,PubMed,10.1099/mic.0.26943-0,,,Human umbilical vein endothelial cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 576,PHI:527,UniProt,Q59L12,EMBL,AAO72959,,,SC5314,ALS3,,,,,,,5476,Candida albicans,5476,CAI4,candidiasis,primates,9606,Homo sapiens (related: human),,,,,cell surface protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,TKB,15256583,PubMed,10.1099/mic.0.26943-0,,,Buccal reconstituted human epithelium,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 577,PHI:528,UniProt,Q6IWN3,EMBL,AAT39367,,,,CLA4,,,,,,,5270,Ustilago maydis,,FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,serine/threonine kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,TKB,15469512,PubMed,10.1111/j.1365-2958.2004.04296.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 578,PHI:529,UniProt,Q5VB04,EMBL,AAT28197,,,,AVR4E,,,,,,,5499,Fulvia fulva,,,leaf mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,other evidence,,,TKB; KHK,10571888,PubMed,10.1046/j.1365-313X.1999.00601.x,"Takken et al., Plant J 1999 Nov;20(3):279-88",jonathan.jones@bbsrc.ac.uk,,Takken et al.,1999,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 579,PHI:530,UniProt,Q8L552,EMBL,AAM20937,,,P6954,AVR1B-1,,,,,,,67593,Phytophthora sojae,67593,P6954,root rot,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,functional test in host: direct injection,,,TKB; KHK,15077672,PubMed,10.1094/MPMI.2004.17.4.394,,,AVR1b-1 protein synthesized in Pichia pastoris and infiltrated into soybean leaves carrying the Rps1b resistance gene triggers a hypersensitive response.,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 580,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Emoy2 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),RIL 3860 line,transgenic recombinant inbred line 3860:RPP1-Nd,UniProt: D9IW02,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,low number blue (GUS) stained cells,resistance hypersensitive response (seen as a reduction in blue stained GUS expressing cells),functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-50,anne.rehmany@warwick.ac.uk,avirulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 581,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Maks9 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,,Maks9,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),RIL 3860 line,transgenic recombinant inbred line 3860:RPP1-Nd,UniProt: D9IW02,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,high number blue (GUS) stained cells,,functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-51,anne.rehmany@warwick.ac.uk,virulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 582,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Noks1 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,,Noks1,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),RIL 3860 line,transgenic recombinant inbred line 3860:RPP1-Nd,UniProt: D9IW02,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,high number blue (GUS) stained cells,,functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-52,anne.rehmany@warwick.ac.uk,virulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 583,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Cala2 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,,Cala2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),RIL 3860 line,transgenic recombinant inbred line 3860:RPP1-Nd,UniProt: D9IW02,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,high number blue (GUS) stained cells,,functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-53,anne.rehmany@warwick.ac.uk,virulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 584,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Emco5 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),RIL 3860 line,transgenic recombinant inbred line 3860:RPP1-Nd,UniProt: D9IW02,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,high number blue (GUS) stained cells,,functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-54,anne.rehmany@warwick.ac.uk,virulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 585,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Emwa1 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,,Emwa1,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),RIL 3860 line,transgenic recombinant inbred line 3860:RPP1-Nd,UniProt: D9IW02,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,high number blue (GUS) stained cells,,functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-55,anne.rehmany@warwick.ac.uk,virulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 586,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Emoy2 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),CW84 line,transgenic line CW84:RPP1WsB,UniProt: Q9LSV1,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,low number blue (GUS) stained cells,resistance hypersensitive response (seen as a reduction in blue stained GUS expressing cells),functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-56,anne.rehmany@warwick.ac.uk,avirulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 587,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Maks9 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,,Maks9,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),CW84 line,transgenic line CW84:RPP1WsB,UniProt: Q9LSV1,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,low number blue (GUS) stained cells,resistance hypersensitive response (seen as a reduction in blue stained GUS expressing cells),functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-57,anne.rehmany@warwick.ac.uk,avirulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 588,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Noks1 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,,Noks1,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),CW84 line,transgenic line CW84:RPP1WsB,UniProt: Q9LSV1,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,low number blue (GUS) stained cells,resistance hypersensitive response (seen as a reduction in blue stained GUS expressing cells),functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-58,anne.rehmany@warwick.ac.uk,avirulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 589,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Cala2 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,,Cala2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),CW84 line,transgenic line CW84:RPP1WsB,UniProt: Q9LSV1,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,high number blue (GUS) stained cells,,functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-59,anne.rehmany@warwick.ac.uk,virulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 590,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Emco5 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),CW84 line,transgenic line CW84:RPP1WsB,UniProt: Q9LSV1,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,low number blue (GUS) stained cells,resistance hypersensitive response (seen as a reduction in blue stained GUS expressing cells),functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-60,anne.rehmany@warwick.ac.uk,"Emco5 is virulent on Ws-0 (susceptible interaction). However, RPP1-WsB is able to recognise an in Planta expressed ATR1NdWsB allele from virulent isolate Emco5. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).",Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 591,PHI:531,UniProt,Q4VKJ6,EMBL,AAX51198,,,Emoy2,ATR1 (ATR1NdWsB),,pK2GW7 Emwa1 ATR1NdWsB test construct (and pK2GW7 uidA for GUS expression in cobombardments),,,,,272952,Hyaloperonospora arabidopsidis,,Emwa1,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),CW84 line,transgenic line CW84:RPP1WsB,UniProt: Q9LSV1,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,high number blue (GUS) stained cells,,functional test in host: transient expression,cobombardment of leaves with an ATR1 test construct and 35S:GUS. detection of product of ATR1NdWsB by RPP1 elicits localized plant cell death (a hypersensitive response) visualized as a reduction in GUS-expressing (blue stained) plant cells.,,AC,15894715,PubMed,10.1105/tpc.105.031807,Plant Cell 2005 Jun;17(6):1839-61,anne.rehmany@warwick.ac.uk,virulent. Differential recognition of ATR1 alleles from different Hpa isolates by RPP1 resistance genes from different Arabidopsis lines (Nd and Ws).,Rehmany et al.,2005,,,AC First Host Target Curation update,2016-01-13,RRes,,,,,,,,,,,,,
,,Record 592,PHI:532,UniProt,Q6R661,EMBL,AAS66948,,,CH5,AVRL567-A,,,,,,,5261,Melampsora lini,,,flax rust,eudicots,4006,Linum usitatissimum (related: flax),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,functional test in host: transient expression,,,TKB; KHK,14973158,PubMed,10.1105/tpc.020040,,,"Transient expression in a host co-expressing L5, L6, or L7 resistance gene leads to hypersensitive response-like necrosis.",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 593,PHI:532,UniProt,Q6R661,EMBL,AAS66948,,,CH5,AVRL567-A,,,,,,,5261,Melampsora lini,,,flax rust,eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,functional test in host: transient expression,,,TKB; KHK,14973158,PubMed,10.1105/tpc.020040,,,"Transient expression in a non-host co-expressing L5, L6, or L7 resistance gene leads to hypersensitive response-like necrosis.",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 594,PHI:533,UniProt,Q6R659,EMBL,AAS66949,,,CH5,AVRL567-b,,,,,,,5261,Melampsora lini,,,flax rust,eudicots,4006,Linum usitatissimum (related: flax),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,functional test in host: transient expression,,,TKB; KHK,14973158,PubMed,10.1105/tpc.020040,,,"Transient expression in a host co-expressing L5, L6, or L7 resistance gene leads to hypersensitive response-like necrosis.",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 595,PHI:533,UniProt,Q6R659,EMBL,AAS66949,,,CH5,AVRL567-b,,,,,,,5261,Melampsora lini,,,flax rust,eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,functional test in host: transient expression,,,TKB; KHK,14973158,PubMed,10.1105/tpc.020040,,,"Transient expression in a non-host co-expressing L5, L6, or L7 resistance gene leads to hypersensitive response-like necrosis.",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 596,PHI:534,UniProt,P78737,EMBL,AAB61464,,,BFP,TOXA,,,,,,,45151,Pyrenophora tritici-repentis,45151,SD-20,tan spot,monocots,4565,Triticum aestivum (related: bread wheat),,,,,protein toxin,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene complementation,,,TKB; KHK,9061946,PubMed,10.1105/tpc.9.2.135,,,Transformation of the ToxA gene into a non-toxin-producing isolate of P. tritici-repentis leads to both toxin production and pathogenicity.,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 597,PHI:535,UniProt,Q2MV46,EMBL,ABB96264,,,CH5,AVRM,,,,,,,5261,Melampsora lini,,,flax rust,eudicots,4006,Linum usitatissimum (related: flax),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,functional test in host: transient expression,,,TKB,16326930,PubMed,10.1105/tpc.105.035980,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 598,PHI:536,UniProt,Q2MV49,EMBL,ABB96261,,,CH5,AVRP4,,,,,,,5261,Melampsora lini,,,flax rust,eudicots,4006,Linum usitatissimum (related: flax),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,functional test in host: transient expression,,,TKB,16326930,PubMed,10.1105/tpc.105.035980,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 599,PHI:537,UniProt,Q2MV43,EMBL,ABB96267,,,CH5,AvrP123,,,,,,,5261,Melampsora lini,,,flax rust,eudicots,4006,Linum usitatissimum (related: flax),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,functional test in host: transient expression,,,TKB,16326930,PubMed,10.1105/tpc.105.035980,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 600,PHI:538,UniProt,Q5XTQ5,EMBL,AAU87358,,,SAS56,FRT1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,fructose transporter,GO:0005353,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,JVK,SH,15950157,PubMed,10.1016/j.fgb.2005.03.001,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 601,PHI:538,UniProt,Q5XTQ5,EMBL,AAU87358,,,SAS56,FRT1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,fructose transporter,GO:0005353,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,JVK,SH,15950157,PubMed,10.1016/j.fgb.2005.03.001,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 602,PHI:540,UniProt,Q8X116,EMBL,CAD21438,,,Bd90,BCPME2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,pectin methylesterase,GO:0030599,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene deletion,,JVK,SH,20565686,PubMed,10.1111/j.1364-3703.2005.00312.x,Kars et al. (2005) MOLECULAR PLANT PATHOLOGY. 6(6) 641-652,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 603,PHI:540,UniProt,Q8X116,EMBL,CAD21438,,,Bd90,BCPME2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,pectin methylesterase,GO:0030599,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene deletion,,JVK,SH,20565686,PubMed,10.1111/j.1364-3703.2005.00312.x,Kars et al. (2005) MOLECULAR PLANT PATHOLOGY. 6(6) 641-652,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 604,PHI:540,UniProt,Q8X116,EMBL,CAD21438,,,Bd90,BCPME2,,,,,,PHI:278,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,pectin methylesterase,GO:0030599,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene deletion,,JVK,SH,20565686,PubMed,10.1111/j.1364-3703.2005.00312.x,Kars et al. (2005) MOLECULAR PLANT PATHOLOGY. 6(6) 641-652,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 605,PHI:540,UniProt,Q8X116,EMBL,CAD21438,,,Bd90,BCPME2,,,,,,PHI:278,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,pectin methylesterase,GO:0030599,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene deletion,,JVK,SH,20565686,PubMed,10.1111/j.1364-3703.2005.00312.x,Kars et al. (2005) MOLECULAR PLANT PATHOLOGY. 6(6) 641-652,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 606,PHI:541,UniProt,Q5XTQ4,EMBL,AAU87359,,,SAS56,LIP1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,lipase,GO:0016298; GO:0004806,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,20565655,PubMed,10.1111/j.1364-3703.2005.00280.x,"Reis et al. (2005) MOLECULAR PLANT PATHOLOGY, 6(3) 257-267",,Phaseolus vulgaris cv. Hiltrud,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 607,PHI:541,UniProt,Q5XTQ4,EMBL,AAU87359,,,SAS56,LIP1,,,,,,PHI:69,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,13546,Gerbera (no common name found),,,,,lipase,GO:0016298; GO:0004806,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,20565655,PubMed,10.1111/j.1364-3703.2005.00280.x,"Reis et al. (2005) MOLECULAR PLANT PATHOLOGY, 6(3) 257-267",,,,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 608,PHI:541,UniProt,Q5XTQ4,EMBL,AAU87359,,,SAS56,LIP1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,lipase,GO:0016298; GO:0004806,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,20565655,PubMed,10.1111/j.1364-3703.2005.00280.x,"Reis et al. (2005) MOLECULAR PLANT PATHOLOGY, 6(3) 257-267",,Tomato cv. Paradiser,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 609,PHI:541,UniProt,Q5XTQ4,EMBL,AAU87359,,,SAS56,LIP1,,,,,,PHI:69,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,lipase,GO:0016298; GO:0004806,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,20565655,PubMed,10.1111/j.1364-3703.2005.00280.x,"Reis et al. (2005) MOLECULAR PLANT PATHOLOGY, 6(3) 257-267",,Tomato cv. Paradiser,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 610,PHI:541,UniProt,Q5XTQ4,EMBL,AAU87359,,,SAS56,LIP1,,,,,,PHI:69,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,lipase,GO:0016298; GO:0004806,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,20565655,PubMed,10.1111/j.1364-3703.2005.00280.x,"Reis et al. (2005) MOLECULAR PLANT PATHOLOGY, 6(3) 257-267",,Phaseolus vulgaris cv. Hiltrud,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 611,PHI:541,UniProt,Q5XTQ4,EMBL,AAU87359,,,SAS56,LIP1,,,,,,PHI:69,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3570,Dianthus caryophyllus (related: clove pink),,,,,lipase,GO:0016298; GO:0004806,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,20565655,PubMed,10.1111/j.1364-3703.2005.00280.x,"Reis et al. (2005) MOLECULAR PLANT PATHOLOGY, 6(3) 257-267",,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 612,PHI:542,UniProt,Q96WN1,EMBL,AAK77951,,,SAS56,BCCAT2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,catalase,GO:0004096,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,,Not in PubMed,10.1046/j.1364-3703.2002.00114.x,"Schouten et al. (2002) MOLECULAR PLANT PATHOLOGY, 3(4) 227-238",,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 613,PHI:542,UniProt,Q96WN1,EMBL,AAK77951,,,SAS56,BCCAT2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,catalase,GO:0004096,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,JVK,SH,,Not in PubMed,10.1046/j.1364-3703.2002.00114.x,"Schouten et al. (2002) MOLECULAR PLANT PATHOLOGY, 3(4) 227-238",,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 614,PHI:543,UniProt,Q96VL9,EMBL,CAC41639,,,SAS56,BCATRD,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,ABC transporter,GO:0042626,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,JVK,SH,,Not in PubMed,10.1016/S0048-3575(02)00015-9,"Hayashi et al. (2002) PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 73, 110-121",,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 615,PHI:543,UniProt,Q96VL9,EMBL,CAC41639,,,SAS56,BCATRD,,,,,,PHI:544,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,ABC transporter,GO:0042626,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,JVK,SH,12324349,PubMed,10.1128/AEM.68.10.4996-5004.2002,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 616,PHI:544,UniProt,Q9P8L8,EMBL,AAF64435,,,SAS56,BCMFS1,,,,,,PHI:543,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MFS transporters,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,JVK,SH,12324349,PubMed,10.1128/AEM.68.10.4996-5004.2002,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 617,PHI:544,UniProt,Q9P8L8,EMBL,AAF64435,,,SAS56,BCMFS1,,,,,,PHI:202,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MFS transporters,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,JVK,SH,12324349,PubMed,10.1128/AEM.68.10.4996-5004.2002,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 618,PHI:544,UniProt,Q9P8L8,EMBL,AAF64435,,,SAS56,BCMFS1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MFS transporters,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,JVK,SH,12324349,PubMed,10.1128/AEM.68.10.4996-5004.2002,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 619,PHI:545,UniProt,Q9HG08,EMBL,AAG23132,,,BC29; BC29,BMP1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAP kinase,"GO:0004707, NAS; GO:0009405, IMP; GO:0044405, IMP; GO:0044409, IMP",GO,,loss of pathogenicity,,yes,,,,,,,,,,,,,,,gene disruption; gene complementation,,JVK,SH,16420354,PubMed,10.1111/j.1365-2958.2005.04991.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 620,PHI:546,UniProt,Q2LMP0,EMBL,AAZ03776,,,SAS56,XYN11A,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,"endo-beta-1,4-xylanase","GO:0009405, IMP; GO:0031176",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,JVK,SH,16404950,PubMed,10.1094/MPMI-19-0025,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 621,PHI:546,UniProt,Q2LMP0,EMBL,AAZ03776,,,SAS56,XYN11A,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,"endo-beta-1,4-xylanase","GO:0009405, IMP; GO:0031176",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,JVK,SH,16404950,PubMed,10.1094/MPMI-19-0025,,,Tested on grape berries,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 622,PHI:547,UniProt,Q6IVV6,EMBL,AAT40313,,,SAS56,CEL5A,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,"endo-beta-1,4-xylanase",GO:0008810,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,JVK,SH,,Not in PubMed,10.1016/j.pmpp.2005.06.005,"Espino et al. (2005) PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY, 66, 213-221",,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 623,PHI:547,UniProt,Q6IVV6,EMBL,AAT40313,,,SAS56,CEL5A,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,13546,Gerbera (no common name found),,,,,"endo-beta-1,4-xylanase",GO:0008810,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,JVK,SH,,Not in PubMed,10.1016/j.pmpp.2005.06.005,"Espino et al. (2005) PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY, 66, 213-221",,Tested on gerbera petals,,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 624,PHI:548,UniProt,Q2LK92,EMBL,ABA25866,,,T4,BcPIC5,,,,,,,40559,Botrytis cinerea,40559,T4,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,unknown,"GO:0009405, IMP; GO:0044419",GO,,reduced virulence,,,,,,,,wild type,,,,,,,,,gene disruption; gene complementation,,JVK,SH; AB,16497329,PubMed,10.1016/j.jmb.2006.01.076,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 625,PHI:548,UniProt,Q2LK92,EMBL,ABA25866,,,T4,BcPIC5,,,,,,,40559,Botrytis cinerea,40559,T4,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,unknown,"GO:0009405, IMP; GO:0044419",GO,,reduced virulence,,,,,,,,wild type,,,,,,,,,gene disruption; gene complementation,,JVK,SH; AB,16497329,PubMed,10.1016/j.jmb.2006.01.076,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 626,PHI:549,UniProt,Q8TG14,EMBL,AAM14606,,,Bd90,BCCHS3a,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3603,Vitis (no common name found),,,,,chitin synthase,"GO:0009405, IMP; GO:0004100; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,"reduced on solid medium, not in liquid medium",,,,,,,,,gene disruption; gene complementation,,JVK,SH; AB,16882034,PubMed,10.1111/j.1462-5822.2006.00711.x,,,Tested on V. vinifera cv Chardonnay leaves,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 627,PHI:549,UniProt,Q8TG14,EMBL,AAM14606,,,Bd90,BCCHS3a,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,chitin synthase,"GO:0009405, IMP; GO:0004100; GO:0044412",GO,,reduced virulence,,no,no,yes,,,,"reduced on solid medium, not in liquid medium",,,,,,,,,gene disruption; gene complementation,,JVK,SH; AB,16882034,PubMed,10.1111/j.1462-5822.2006.00711.x,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 628,PHI:550,UniProt,Q8X1E7,EMBL,AAL37947,,,L,BOS1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,histidine kinase,"GO:0009405, IMP; GO:0004673; GO:0016772",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,JVK,SH,16941908,PubMed,10.1094/MPMI-19-1042,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 629,PHI:550,UniProt,Q8X1E7,EMBL,AAL37947,,,L,BOS1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,histidine kinase,"GO:0009405, IMP; GO:0004673; GO:0016772",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,JVK,SH,16941908,PubMed,10.1094/MPMI-19-1042,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 630,PHI:551,UniProt,Q9C1U1,EMBL,BAB40947,,,,HIK1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,histidine kinase,GO:0000155,GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; MU,15707841,PubMed,10.1016/j.fgb.2004.11.002,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 631,PHI:552,UniProt,Q96WM9,EMBL,AAK77953,,,SAS56,BcLCC2,,,,,,,40559,Botrytis cinerea,40559,SAS56,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,Laccase2,GO:0008471,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,JVK,SH,11929539,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 632,PHI:552,UniProt,Q96WM9,EMBL,AAK77953,,,SAS56,BcLCC2,,,,,,,40559,Botrytis cinerea,40559,SAS56,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,Laccase2,GO:0008471,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,JVK,SH,11929539,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 633,PHI:552,UniProt,Q96WM9,EMBL,AAK77953,,,SAS56,BcLCC2,,,,,,,40559,Botrytis cinerea,40559,SAS56,grey mold,eudicots,3603,Vitis (no common name found),,,,,Laccase2,GO:0008471,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,JVK,SH,11929539,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 634,PHI:552,UniProt,Q96WM9,EMBL,AAK77953,,,SAS56,BcLCC2,,,,,,,40559,Botrytis cinerea,40559,SAS56,grey mold,eudicots,3818,Arachis hypogaea (related: peanut),,,,,Laccase2,GO:0008471,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,JVK,SH,11929539,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 635,PHI:553,UniProt,Q8ZPP5,EMBL,AAL20316,,,LT2; SGSC 1412; ATCC 700720,ssrA,SPI2,,,,,PHI:554,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0030254, NAS; GO:0030257, NAS; GO:0044412, IGI; GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 636,PHI:553,UniProt,Q8ZPP5,EMBL,AAL20316,,,LT2; SGSC 1412; ATCC 700720,ssrA,SPI2,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,10692360,PubMed,10.1128/jb.182.6.1558-1563.2000,,,Signature-tagged mutagenesis (STM); Tested in BALB/cJ mice (isolated from spleen); ssrA is required for expression of ivi genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 637,PHI:554,UniProt,Q8XFU4,EMBL,AAO68911,,,Ty2,ssrB,SPI2,,,,,PHI:553,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0030254, NAS; GO:0030257, NAS; GO:0044412, IGI; GO:0009405, IGI",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 638,PHI:555,UniProt,P0CZ04,EMBL,AAL20317,,,LT2; SGSC 1412; ATCC 700720,ssaB,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0030254, NAS; GO:0030257, NAS; GO:0044412, IMP; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 639,PHI:556,UniProt,Q8Z6L6,EMBL,AAO68920,,,Ty2,sseC,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0030254, NAS; GO:0030257, NAS; GO:0044412, IMP; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 640,PHI:557,UniProt,Q8Z6L8,EMBL,AAO68922,,,Ty2,sseE,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0030254, NAS; GO:0030257, NAS; GO:0044412, IMP; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 641,PHI:558,UniProt,Q8Z6M0,EMBL,AAO68924,,,Ty2,sseF,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0030254, NAS; GO:0030257, NAS; GO:0044412, IMP; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 642,PHI:559,UniProt,Q8Z7H8,EMBL,AAO69321,,,Ty2,sifA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 643,PHI:560,UniProt,P96058,EMBL,AAO68606,,,Ty2,sirA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0009405, IMP; GO:0044409, NAS; GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells with polar and nonpolar mutants,Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 644,PHI:561,UniProt,Q8Z4A4,EMBL,AAO70332,,,Ty2,orgA,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,macrophage,,"GO:0030254, NAS; GO:0030257, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,RK,SH; AC,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 645,PHI:561,UniProt,Q8Z4A4,EMBL,AAO70332,,,Ty2,orgA,SPI1,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,10569754,PubMed,no data found,Tsolis et al. (1999) Infection and Immunity 67(12): 6385-6393,abaumler@tamu.edu,Signature-tagged mutagenesis (STM); Tested in BALB/cJ mice (isolated from spleen and Peyer's patches),Tsolis et al.,1999,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 646,PHI:562,UniProt,Q8Z445,EMBL,AAO70423,,,Ty2,barA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,macrophage,,"GO:0030254, NAS; GO:0030257, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,RK,SH; AC,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 647,PHI:563,UniProt,P43015,EMBL,AAL21756,,,LT2; SGSC 1412; ATCC 700720,hilA,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells with polar and nonpolar mutants,Chan et al.,2005,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 648,PHI:563,UniProt,P43015,EMBL,AAL21756,,,LT2; SGSC 1412; ATCC 700720,hilA,SPI1,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,gastroenteritis,even-toed ungulates,9913,Bos taurus (related: cattle),,,,,,"GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,10569754,PubMed,no data found,,,Signature-tagged mutagenesis (STM); Tested in Holstein-Friesian calves (isolated from spleen and Peyer's patches),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 649,PHI:563,UniProt,P43015,EMBL,AAL21756,,,LT2; SGSC 1412; ATCC 700720,hilA,SPI1,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,10569754,PubMed,no data found,,,Signature-tagged mutagenesis (STM); Tested in BALB/cJ mice (isolated from spleen and Peyer's patches),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 650,PHI:564,UniProt,Q92197,EMBL,CAA63929,,,H237,chsC,,,,,,PHI:565,746128,Aspergillus fumigatus,,H237,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,chitin synthase,"GO:0004100, NAS; GO:0009405, IGI; GO:0051701, IGI",GO,,reduced virulence,,,,,,,,reduced,wild type,,,,,,,,gene disruption,,,SH,8736545,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 651,PHI:565,UniProt,P54267,EMBL,CAA63928,,,H237,chsG,,,,,,PHI:564,746128,Aspergillus fumigatus,,H237,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,chitin synthase,"GO:0004100, NAS; GO:0009405, IGI; GO:0051701, IGI",GO,,reduced virulence,,,,,,,,reduced,wild type,,,,,,,,gene disruption,,,SH,8736545,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 652,PHI:566,UniProt,Q9C1F9,EMBL,AAK19621,,,,cel2,,,,,,,5017,Bipolaris zeicola,,367-1a,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-glucanase","GO:0008810, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; JA,11471744,PubMed,10.1271/bbb.65.1406,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 653,PHI:567,UniProt,P0CT48,EMBL,AAC41683,,,Ken60-19,XYL1 (XYN22),,,,,,PHI:568,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 654,PHI:567,UniProt,P0CT48,EMBL,AAC41683,,,Ken60-19,XYL1 (XYN22),,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 655,PHI:567,UniProt,P0CT48,EMBL,AAC41683,,,Ken60-19,XYL1 (XYN22),,,,,,PHI:568,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 656,PHI:567,UniProt,P0CT48,EMBL,AAC41683,,,Ken60-19,XYL1 (XYN22),,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,38414,Eragrostis curvula (related: weeping love grass),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 657,PHI:567,UniProt,P0CT48,EMBL,AAC41683,,,Ken60-19,XYL1 (XYN22),,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 658,PHI:567,UniProt,P0CT48,EMBL,AAC41683,,,Ken60-19,XYL1 (XYN22),,,,,,PHI:568,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,38414,Eragrostis curvula (related: weeping love grass),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 659,PHI:568,UniProt,Q01176,EMBL,AAC41684,,,Ken60-19,XYL2 (XYN33),,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,38414,Eragrostis curvula (related: weeping love grass),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 660,PHI:568,UniProt,Q01176,EMBL,AAC41684,,,Ken60-19,XYL2 (XYN33),,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 661,PHI:568,UniProt,Q01176,EMBL,AAC41684,,,Ken60-19,XYL2 (XYN33),,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 662,PHI:568,UniProt,Q01176,EMBL,AAC41684,,,Ken60-19,XYL2 (XYN33),,,,,,PHI:567,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 663,PHI:568,UniProt,Q01176,EMBL,AAC41684,,,Ken60-19,XYL2 (XYN33),,,,,,PHI:567,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 664,PHI:568,UniProt,Q01176,EMBL,AAC41684,,,Ken60-19,XYL2 (XYN33),,,,,,PHI:567,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,38414,Eragrostis curvula (related: weeping love grass),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH; MU,,Not in PubMed,10.1094/MPMI.1997.10.6.700,Wu et al. (1997) MOLECULAR PLANT-MICROBE INTERACTIONS 10(6) 700-708,,rice cv. Sariceltik,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 665,PHI:569,UniProt,O59937,EMBL,AAC06239,,,42-87,XYL3,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption,,,SH; AB,11929211,PubMed,10.1006/fgbi.2001.1318,,,Fruit and root infection,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 666,PHI:570,UniProt,Q9C1R1,EMBL,AAK27975,,,,XYL4,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,no,no,no,,,,,,,,,,,,,gene disruption,,,SH; AB,11929211,PubMed,10.1006/fgbi.2001.1318,,,Fruit and root infection,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 667,PHI:571,UniProt,Q06562,EMBL,AAA33024,,,SB111,XYL1,,,,,,PHI:572; PHI:573,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 668,PHI:571,UniProt,Q06562,EMBL,AAA33024,,,SB111,XYL1,,,,,,,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 669,PHI:571,UniProt,Q06562,EMBL,AAA33024,,,SB111,XYL1,,,,,,PHI:573,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 670,PHI:571,UniProt,Q06562,EMBL,AAA33024,,,SB111,XYL1,,,,,,PHI:572,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 671,PHI:572,UniProt,Q00350,EMBL,AAC62815,,,SB111,XYL2,,,,,,,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 672,PHI:572,UniProt,Q00350,EMBL,AAC62815,,,SB111,XYL2,,,,,,PHI:573,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 673,PHI:572,UniProt,Q00350,EMBL,AAC62815,,,SB111,XYL2,,,,,,PHI:571,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 674,PHI:572,UniProt,Q00350,EMBL,AAC62815,,,SB111,XYL2,,,,,,PHI:571; PHI:573,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 675,PHI:573,UniProt,Q00351,EMBL,AAC62816,,,SB111,XYL3,,,,,,PHI:571,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 676,PHI:573,UniProt,Q00351,EMBL,AAC62816,,,SB111,XYL3,,,,,,PHI:572,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 677,PHI:573,UniProt,Q00351,EMBL,AAC62816,,,SB111,XYL3,,,,,,,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 678,PHI:573,UniProt,Q00351,EMBL,AAC62816,,,SB111,XYL3,,,,,,PHI:571; PHI:572,5017,Bipolaris zeicola,,SB111,leaf spot,monocots,4577,Zea mays (related: maize),,,,,"endo-beta-1,4-xylanase","GO:0031176, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,SH; JA,8900004,PubMed,no data found,,,pathogen formerly called Cochliobolus carbonum teleomorph name,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 679,PHI:574,UniProt,Q589C6,EMBL,BAD93277,,,IuRy-1,BCG3,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,G protein alpha subunit,"GO:0009405, IMP; GO:0004871; GO:0044412",GO,,reduced virulence,,no,yes,no,,,,,wild type,,,,,,,,gene disruption; gene complementation,,JVK,SH,16420354,PubMed,10.1111/j.1365-2958.2005.04991.x,,,Addition of CPT-cAMP restores lesion development to wild-type levels,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 680,PHI:576,UniProt,Q2PEP0,EMBL,BAE72680,,,Fl1,NoxA,,,,,,,35717,Epichloe festucae,877507,Fl1,,monocots,4608,Festuca pratensis (related: meadow ryegrass),,,,,NADPH oxidase,,,,enhanced antagonism,,,,,,,,reduced aerial hyphae,,,,,,,,,gene disruption; gene complementation,,,TKB; AB,16517760,PubMed,10.1105/tpc.105.039263,,,Meadow fescue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 681,PHI:576,UniProt,Q2PEP0,EMBL,BAE72680,,,Fl1,NoxA,,,,,,,35717,Epichloe festucae,877507,Fl1,,monocots,4522,Lolium perenne (related: perennial ryegrass),,,,,NADPH oxidase,,,,enhanced antagonism,,,,,,,,reduced aerial hyphae,,,,,,,,,gene disruption; gene complementation,,,TKB; AB,16517760,PubMed,10.1105/tpc.105.039263,,,Perennial ryegrass,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 682,PHI:576,UniProt,Q2PEP0,EMBL,BAE72680,,,Fl1,NoxA,,,,,,,35717,Epichloe festucae,877507,Fl1,,monocots,4606,Lolium arundinaceum (related: tall fescue),,,,,NADPH oxidase,,,,enhanced antagonism,,,,,,,,reduced aerial hyphae,,,,,,,,,gene disruption; gene complementation,,,TKB; AB,16517760,PubMed,10.1105/tpc.105.039263,,,Tall fescue,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 683,PHI:577,UniProt,Q2PEN8,EMBL,BAE72682,,,Fl1,NoxB,,,,,,,35717,Epichloe festucae,877507,Fl1,,monocots,4522,Lolium perenne (related: perennial ryegrass),,,,,NADPH oxidase,,,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene deletion,,,TKB; AB,16517760,PubMed,10.1105/tpc.105.039263,,,Perennial ryegrass wild-type mutualism,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 684,PHI:578,UniProt,A0JC82,EMBL,BAF36501,,,Fl1,NoxR,,,,,,,35717,Epichloe festucae,877507,Fl1,,monocots,4522,Lolium perenne (related: perennial ryegrass),,,,,NADPH oxidase,,,,enhanced antagonism,,,,,,,,wild type,,,,,,,,,gene deletion,,,TKB; AB,17041146,PubMed,10.1105/tpc.106.046169,,,Perennial ryegrass,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 685,PHI:579,UniProt,Q888W3,EMBL,AAO54435,,,DC3000,hopAG,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 686,PHI:579,UniProt,Q888W3,EMBL,AAO54435,,,DC3000,hopAG,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 687,PHI:580,UniProt,Q87WF4,EMBL,AAO58043,,,DC3000,hopS1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 688,PHI:580,UniProt,Q87WF4,EMBL,AAO58043,,,DC3000,hopS1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 689,PHI:581,UniProt,Q888W1,EMBL,AAO54439,,,DC3000,hopAH1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 690,PHI:581,UniProt,Q888W1,EMBL,AAO54439,,,DC3000,hopAH1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 691,PHI:582,UniProt,Q888W0,EMBL,AAO54440,,,DC3000,hopAI1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 692,PHI:582,UniProt,Q888W0,EMBL,AAO54440,,,DC3000,hopAI1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 693,PHI:583,UniProt,Q87WF8,EMBL,AAO58038,,,DC3000,hopO1-3,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 694,PHI:583,UniProt,Q87WF8,EMBL,AAO58038,,,DC3000,hopO1-3,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 695,PHI:584,UniProt,Q87WF7,EMBL,AAO58039,,,DC3000,hopT1-2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 696,PHI:584,UniProt,Q87WF7,EMBL,AAO58039,,,DC3000,hopT1-2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 697,PHI:585,UniProt,Q888V9,EMBL,AAO54441,,,DC3000,PSPTO0907,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 698,PHI:585,UniProt,Q888V9,EMBL,AAO54441,,,DC3000,PSPTO0907,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,,,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,SH,17073301,PubMed,10.1094/MPMI-19-1180,,,constitutively expressing normally cryptic or disrupted hop genes,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 699,PHI:586,UniProt,Q88BP8,EMBL,AAO59043,,,DC3000,hopO1-1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III effector,"GO:0051701, IMP; GO:0030581, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,SH,15937188,PubMed,10.1128/JB.187.12.4257-4269.2005,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 700,PHI:587,UniProt,Q889C0,EMBL,AAO54374,,,DC3000,PSPTO0834,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,alkohol dehydrogenase,"GO:0004022, NAS; GO:0044412, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,SH,17073302,PubMed,10.1094/MPMI-19-1193,,,"PSPPH3759 alcohol dehydrogenase homolog (pv. Phaseolicola 1448A), Hrp promotor, no function related to the T3SS",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 701,PHI:588,UniProt,Q884I7,EMBL,AAO55623,,,DC3000,PSPTO2105,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,ApbE-family protein,"GO:0009228, TAS; GO:0009405, IMP; GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,SH,17073302,PubMed,10.1094/MPMI-19-1193,,,"PSPPH1855 alcohol dehydrogenase homolog (pv. Phaseolicola 1448A), Hrp promotor, no function related to the T3SS",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 702,PHI:589,UniProt,Q48B68,EMBL,AAZ37987,,,1448A; BAA-978,avrD1,,,,,,,317,Pseudomonas syringae,264730,pv. phaseolicola strain 1448A,halo blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III effector,"GO:0015448, IDA",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene disruption,,,SH,17073302,PubMed,10.1094/MPMI-19-1193,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 703,PHI:590,UniProt,Q48BC6,EMBL,AAZ38005,,,1448A; BAA-978,HopAU1,,,,,,,317,Pseudomonas syringae,264730,pv. phaseolicola strain 1448A,halo blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,shikimate kinase,"GO:0004765, NAS; GO:0015448, IDA",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene disruption,,,SH,17073302,PubMed,10.1094/MPMI-19-1193,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 704,PHI:591,UniProt,Q96V66,EMBL,AAK51698,,,,ORP1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,unknown,"GO:0009405, IMP; GO:0044409, IMP",GO,,loss of pathogenicity,,,yes,,,,,,,,,,,,,,gene disruption; gene complementation,,DS,AB; MU,11277428,PubMed,10.1094/MPMI.2001.14.3.308,,Marc-Henri.Lebrun@Aventis.com,Transposon mutagenesis. Differentiated melanized appressoria but could not penetrate rice leaves,Villalba et al.,2001,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 705,PHI:591,UniProt,Q96V66,EMBL,AAK51698,,,,ORP1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,unknown,"GO:0009405, IMP; GO:0044409, IMP",GO,,loss of pathogenicity,,,yes,,,,,,,,,,,,,,gene disruption; gene complementation,,DS,AB; MU,11277428,PubMed,10.1094/MPMI.2001.14.3.308,,Marc-Henri.Lebrun@Aventis.com,Transposon mutagenesis. Differentiated melanized appressoria but could not penetrate rice leaves,Villalba et al.,2001,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 706,PHI:593,UniProt,Q0PND8,EMBL,ABG79929,,,Guy11,PEX6,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,,"GO:0009405, IMP; GO:0044409, IMP",GO,,loss of pathogenicity,,yes,yes,,,,,,,,,,,,,,gene disruption; gene complementation,,DS,AB; MU,16824095,PubMed,10.1111/j.1365-2958.2006.05194.x,Ramos-Pamplona et al. (2006) MOLECULAR MICROBIOLOGY 61(1): 61-75,naweed@tll.org.sg,,Ramos-Pamplona et al.,2006,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 707,PHI:593,UniProt,Q0PND8,EMBL,ABG79929,,,Guy11,PEX6,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,"GO:0009405, IMP; GO:0044409, IMP",GO,,loss of pathogenicity,,yes,yes,,,,,,,,,,,,,,gene disruption; gene complementation,,DS,AB; MU,16824095,PubMed,10.1111/j.1365-2958.2006.05194.x,Ramos-Pamplona et al. (2006) MOLECULAR MICROBIOLOGY 61(1): 61-75,naweed@tll.org.sg,,Ramos-Pamplona et al.,2006,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 708,PHI:594,UniProt,O42620,EMBL,AAB88887,,,4091-5-8,CrAT1 (PTH2),,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,carnitine-dependent acetyl unit transport from peroxisomes,"GO:0009405, IMP; GO:0044409, IMP",GO,,loss of pathogenicity,,yes,yes,,,,,,,,,,,,,,gene disruption,,,AB; MU,16824095,PubMed,10.1111/j.1365-2958.2006.05194.x,Ramos-Pamplona et al. (2006) MOLECULAR MICROBIOLOGY 61(1): 61-75,naweed@tll.org.sg,,Ramos-Pamplona et al.,2006,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 709,PHI:595,UniProt,Q1L2E2,EMBL,AAZ95011,,,,ALS1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),,,,,ALA synthase,"GO:0009405, IMP; GO:0044409, IMP; GO:0044412, IMP",GO,,reduced virulence,,,yes,yes,,,,,,,,,,,,,gene disruption; gene complementation,,DS; RO,AB; AC,16622070,PubMed,10.1099/mic.0.28556-0,Solomon et al. (2006) Microbiology 152(5):1533-1538,psolomon@murdoch.edu.au,Lesions reduced. Severely stunted germs tubes leading to death. Auxotrophic for ALA; with complementation by ALA,Solomon et al.,2006,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 710,PHI:596,UniProt,B6VCT7,EMBL,ACJ06588,,,,ATG8,,,,,,,318829,Magnaporthe oryzae,,Guy11; H3:eGFP,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,autophagy,"GO:0009405, IMP; GO:0044409, IMP",GO,,loss of pathogenicity,,yes,yes,,,,,,,,,,,,,,gene disruption; gene complementation,,DS,AB; MU,16645096,PubMed,10.1126/science.1124550,,n.j.talbot@exeter.ac.uk,Impaired autophagy of infection conidium preventing appressorium formation.,Veneault-Fourrey et al,2006,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 711,PHI:597,UniProt,Q7Z7W8,EMBL,AAP40632,,,M1,LOPB,,,,,,,5022,Leptosphaeria maculans,,M1,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,unknown,"GO:0009405, IMP; GO:0044412, IMP",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,altered gene expression / gene regulation,,AI; BH,AB; AC,12742061,PubMed,10.1016/S1087-1845(02)00588-1,Idnurm and Howlett (2003) Fungal Genetics and Biology 39: 31-7,bhowlett@unimelb.edu.au,Promoter disruption,Idnurm and Howlett,2003,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 712,PHI:598,UniProt,Q0QWD8,EMBL,ABB55459,,,IBCN18,THIOL,,,,,,,5022,Leptosphaeria maculans,,ICBN 18,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,3-ketoacyl-CoA thiolase,"GO:0009405, IMP; GO:0044412, IMP",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,altered gene expression / gene regulation: overexpression,,AI; BH,AB; AC,16776292,PubMed,10.1094/MPMI-19-0588,Elliott and Howlett (2006) Molecular Plant Microbe Interactions 19: 588-96,bhowlett@unimelb.edu.au,Phenotype due to overexpression of THIOL gene; Promotor disruption,Elliott and Howlett,2006,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 713,PHI:599,UniProt,Q1A1Y7,EMBL,ABD49452,,,H99,TCO1,,,,,,,5207,Cryptococcus neoformans,235443,serotype A strain H99; serotype A strain KN99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,putative histidine sensor kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,AB; KHK,16672377,PubMed,10.1091/mbc.E06-02-0113,,heitm001@duke.edu,Mating defective,Bahn et al.,2006,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 714,PHI:600,UniProt,Q9P4A1,EMBL,AAF63734,,,H99,CBP1,,,,,,,5207,Cryptococcus neoformans,,serotype A strain M049,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,calcineurin binding protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,AB; KHK,10899116,PubMed,10.1093/emboj/19.14.3618,,heitm001@duke.edu,,Gorlach et al,2000,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 715,PHI:600,UniProt,Q9P4A1,EMBL,AAU11489,,,H99,CBP1,,,,,,,5207,Cryptococcus neoformans,,serotype A strain M049,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,calcineurin binding protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,AB; KHK,10899116,PubMed,10.1093/emboj/19.14.3618,,heitm001@duke.edu,,Gorlach et al,2000,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 716,PHI:601,UniProt,Q8ZPP8,EMBL,AAL20303,,,LT2; SGSC 1412; ATCC 700720,orf48,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 717,PHI:602,UniProt,H9L471,EMBL,AAL20314,,,LT2; SGSC 1412; ATCC 700720,orf242,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 718,PHI:603,UniProt,P0A1T4,EMBL,AAL20312,,,LT2; SGSC 1412; ATCC 700720,orf70,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 719,PHI:604,UniProt,Q9Z4S8,EMBL,AAO68905,,,Ty2,ttrB,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,tetrathionate reductase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 720,PHI:605,UniProt,Q83T39,EMBL,AAO68906,,,Ty2,ttrS,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,tetrathionate reductase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 721,PHI:606,UniProt,Q9Z4T0,EMBL,AAO68907,,,Ty2,ttrR,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,tetrathionate reductase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 722,PHI:607,UniProt,H9L495,EMBL,AAL20318,,,LT2; SGSC 1412; ATCC 700720,ssaC,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 723,PHI:608,UniProt,Q8Z6M9,EMBL,AAO68934,,,Ty2,ssaV,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 724,PHI:609,UniProt,Q8Z4N6,EMBL,AAO68047,,,Ty2,sseA,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 725,PHI:610,UniProt,Q8Z6M8,EMBL,AAO68933,,,Ty2,ssaM,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 726,PHI:611,UniProt,H9L4C4,EMBL,AAL20305,,,LT2; SGSC 1412; ATCC 700720,orf245,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 727,PHI:612,UniProt,H9L428,EMBL,AAL20306,,,LT2; SGSC 1412; ATCC 700720,orf408,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 728,PHI:613,UniProt,H9L495,EMBL,AAL20318,,,LT2; SGSC 1412; ATCC 700720,ssaC,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 729,PHI:614,UniProt,Q8Z6L2,EMBL,AAO68915,,,Ty2,ssaD,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 730,PHI:615,UniProt,Q8Z6L3,EMBL,AAO68916,,,Ty2,ssaE,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 731,PHI:616,UniProt,Q8Z4N6,EMBL,AAO68047,,,Ty2,sseA,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 732,PHI:617,UniProt,Q8Z6L7,EMBL,AAO68921,,,Ty2,sseD,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 733,PHI:618,UniProt,Q8Z6L9,EMBL,AAO68923,,,Ty2,sscB,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 734,PHI:619,UniProt,Q8Z6M3,EMBL,AAO68928,,,Ty2,ssaI,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 735,PHI:620,UniProt,Q8Z6M4,EMBL,AAO68929,,,Ty2,ssaJ,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 736,PHI:621,UniProt,P74853,EMBL,AAL20335,,,LT2; SGSC 1412; ATCC 700720; LT2; SGSC 1412; ATCC 700720,ssaK,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 737,PHI:622,UniProt,Q8Z6M7,EMBL,AAO68932,,,Ty2,ssaL,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 738,PHI:623,UniProt,Q8Z6M8,EMBL,AAO68933,,,Ty2,ssaM,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 739,PHI:624,UniProt,Q8Z6N0,EMBL,AAO68935,,,Ty2,ssaN,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 740,PHI:625,UniProt,P0A240,EMBL,AAO68937,,,Ty2,ssaP,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 741,PHI:626,UniProt,Q8Z6N2,EMBL,AAO68938,,,Ty2,ssaQ,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 742,PHI:627,UniProt,Q8Z6N3,EMBL,AAO68939,,,Ty2,yscR,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 743,PHI:628,UniProt,Q8Z6N4,EMBL,AAO68940,,,Ty2,ssaS,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 744,PHI:629,UniProt,Q8Z6N5,EMBL,AAO68941,,,Ty2,ssaT,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 745,PHI:630,UniProt,Q8Z6N6,EMBL,AAO68942,,,Ty2,ssaU,SPI2,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,type III secretion,"GO:0009405, IMP; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 746,PHI:631,UniProt,P0CL09,EMBL,AAL21747,,,LT2; SGSC 1412; ATCC 700720,hilC,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 747,PHI:632,UniProt,Q8Z4A2,EMBL,AAO70334,,,Ty2,prgK,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 748,PHI:633,UniProt,Q8Z4A1,EMBL,AAO70335,,,Ty2,prgJ,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 749,PHI:634,UniProt,Q8Z499,EMBL,AAO70337,,,Ty2,prgH,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 750,PHI:634,UniProt,Q8Z499,EMBL,AAO70337,,,Ty2,prgH,SPI1,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14029,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,10569754,PubMed,no data found,,,Signature-tagged mutagenesis (STM); Tested in BALB/cJ mice (isolated from spleen and Peyer's patches),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 751,PHI:634,UniProt,Q8Z499,EMBL,AAO70337,,,Ty2,prgH,SPI1,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14029,gastroenteritis,even-toed ungulates,9913,Bos taurus (related: cattle),,,,,,"GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,10569754,PubMed,no data found,,,Signature-tagged mutagenesis (STM); Tested in Holstein-Friesian calves (isolated from Peyer's patches),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 752,PHI:635,UniProt,P0CL08,EMBL,AAL21755,,,LT2; SGSC 1412; ATCC 700720,hilD,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 753,PHI:636,UniProt,P43018,EMBL,AAO70340,,,Ty2,iagB,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 754,PHI:637,UniProt,P74849,EMBL,AAO70345,,,Ty2,sipA,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 755,PHI:638,UniProt,Q56134,EMBL,AAO70348,,,Ty2,sipB,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 756,PHI:639,UniProt,P69066,EMBL,AAL21766,,,LT2; SGSC 1412; ATCC 700720; LT2; SGSC 1412; ATCC 700720,sicA,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 757,PHI:640,UniProt,Q8Z492,EMBL,AAO70350,,,Ty2,spaS,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 758,PHI:641,UniProt,Q8Z491,EMBL,AAO70351,,,Ty2,spaR,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 759,PHI:642,UniProt,Q56023,EMBL,AAO70353,,,Ty2,spaP,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells and BALB/cJ mice (isolated from spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 760,PHI:643,UniProt,Q56022,EMBL,AAO70354,,,Ty2,spaO,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 761,PHI:644,UniProt,P40612,EMBL,AAL21773,,,LT2; SGSC 1412; ATCC 700720,invI,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 762,PHI:645,UniProt,P0A1B9,EMBL,AAL21774,,,LT2; SGSC 1412; ATCC 700720,invC,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 763,PHI:646,UniProt,P0A1N0,EMBL,AAL21775,,,LT2; SGSC 1412; ATCC 700720,invB,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 764,PHI:647,UniProt,P0A1I4,EMBL,AAO70359,,,Ty2,invA,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 765,PHI:648,UniProt,Q56052,EMBL,AAO70360,,,Ty2,invE,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 766,PHI:649,UniProt,Q8Z489,EMBL,AAO70361,,,Ty2,invG,SPI1,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0030254, NAS; GO:0030257, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,16113260,PubMed,10.1128/IAI.73.9.5438-5449.2005,Chan et al. (2005) Infection and Immunity 73(9): 5438-5449,kchan47@gmail.com,Signature-tagged mutagenesis (STM); Tested in RAW 264.7 macrophage- like cells,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 767,PHI:650,UniProt,Q156F5,EMBL,ABG25558,,,,TPS1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,trehalose-6-phosphate synthase,"GO:0005946, NAS; GO:0003825, NAS",GO,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene disruption,,JVK,SH,16946258,PubMed,10.1099/mic.0.29044-0,,,Germination in full medium: unaffected; important for heat protection,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 768,PHI:651,UniProt,Q156F4,EMBL,ABG25559,,,,TRE1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,neutral trehalase,"GO:0015927, NAS; GO:0030437, IMP",GO,,unaffected pathogenicity,,,,,,reduced,,wild type,,,,,,,,,gene disruption,,JVK,SH,16946258,PubMed,10.1099/mic.0.29044-0,,,Germination in full medium: unaffected; Germination in minimal medium (low amounts of sugar): delayed,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 769,PHI:652,UniProt,Q945U0,EMBL,AAL11720,,,,GIP1,,,,,,,67593,Phytophthora sojae,,,root rot,eudicots,3847,Glycine max (related: soybean),,,,,glucanase inhibitor protein,"GO:0004857, TAS; GO:0044413, IPI",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,biochemical analysis,,SK,SH,12084830,PubMed,10.1105/tpc.002253,,,"interacts with endo-beta-1,3-glucanase (EGaseA), but not with EGaseB",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 770,PHI:653,UniProt,Q945T9,EMBL,AAL11721,,,,GIP2,,,,,,,67593,Phytophthora sojae,,,root rot,eudicots,3847,Glycine max (related: soybean),,,,,glucanase inhibitor protein,"GO:0004857, TAS; GO:0044413, IPI",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,biochemical analysis,,SK,SH,12084830,PubMed,10.1105/tpc.002253,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 771,PHI:656,UniProt,Q8H6Z6,EMBL,AAN31500,,,DDR7602,crn1,,,,,,,4787,Phytophthora infestans,887080,90128,late blight,eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,SK,SH,12840044,PubMed,10.1101/gr.910003,,,crn2 always causing faster and more severe necrosis than crn1,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 772,PHI:656,UniProt,Q8H6Z6,EMBL,AAN31500,,,DDR7602,crn1,,,,,,,4787,Phytophthora infestans,887080,90128,late blight,eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,SK,SH,12840044,PubMed,10.1101/gr.910003,,,crn2 always causing faster and more severe necrosis than crn1,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 773,PHI:656,UniProt,Q8H6Z6,EMBL,AAN31500,,,DDR7602,crn1,,,,,,,4787,Phytophthora infestans,887080,90128,late blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,SK,SH,12840044,PubMed,10.1101/gr.910003,,,crn2 always causing faster and more severe necrosis than crn1,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 774,PHI:657,UniProt,Q8H6Z4,EMBL,AAN31502,,,DDR7602,crn2,,,,,,,4787,Phytophthora infestans,887080,90128,late blight,eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,SK,SH,12840044,PubMed,10.1101/gr.910003,,,crn2 always causing faster and more severe necrosis than crn1,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 775,PHI:657,UniProt,Q8H6Z4,EMBL,AAN31502,,,DDR7602,crn2,,,,,,,4787,Phytophthora infestans,887080,90128,late blight,eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,SK,SH,12840044,PubMed,10.1101/gr.910003,,,crn2 always causing faster and more severe necrosis than crn1,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 776,PHI:657,UniProt,Q8H6Z4,EMBL,AAN31502,,,DDR7602,crn2,,,,,,,4787,Phytophthora infestans,887080,90128,late blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,SK,SH,12840044,PubMed,10.1101/gr.910003,,,crn2 always causing faster and more severe necrosis than crn1,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 777,PHI:658,UniProt,Q9AXL8,EMBL,AAM48170,,,P6497,PsojNIP,,,,,,,67593,Phytophthora sojae,67593,race 2 strain P6497,root rot,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,SK,SH,12410814,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 778,PHI:659,UniProt,Q6TA23,EMBL,AAR05401,,,P7064,Avr1b-1,,,,,,,67593,Phytophthora sojae,67593,race 7 strain P7064,root rot,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: direct injection,,SK,SH,15077672,PubMed,10.1094/MPMI.2004.17.4.394,,,Avr1b-1 interacts with Rps1b and less with Rps1k; Infiltration of higher concentrations: necrosis spreads to the entire mid and upper regions of the plants,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 779,PHI:660,UniProt,O42830,EMBL,CAA65843,,,,CBEL (GP34),,,,,,,4792,Phytophthora nicotianae,1368100,var. nicotianae race 0,buckeye rot (potato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,LOX activity,biochemical analysis,,SK,SH,9390419,PubMed,10.1094/MPMI.1997.10.9.1045,Sejalon-Delmas et al. (1997) PHYTOPATHOLOGY 87: 899-909,,pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 780,PHI:661,UniProt,P74865,EMBL,AAC44302,,,LT2; SGSC 1412; ATCC 700720; LT2; SGSC 1412; ATCC 700720,spiB,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,10569754,PubMed,no data found,,,Signature-tagged mutagenesis (STM); Tested in BALB/cJ mice (isolated from spleen and Peyer's patches),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 781,PHI:662,UniProt,P13041,EMBL,AAL23532,,,SGSC1412,spvR,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,10569754,PubMed,no data found,,,Signature-tagged mutagenesis (STM); Tested in BALB/cJ mice (Peyer's patches),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 782,PHI:663,UniProt,H9L477,EMBL,AAL23530,,,SGSC1412; SGSC1412; SGSC1412,spvB,pSLT,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0044412, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,other evidence,,RK,SH,10569754,PubMed,no data found,,,Signature-tagged mutagenesis (STM); Tested in BALB/cJ mice (Peyer's patches and spleen),,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 783,PHI:664,UniProt,Q9SPD4,GenBank,AAD53944,,,,PaNie,,,,,,,65070,Pythium aphanidermatum,,,,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: direct injection,,SK,SH,11706166,PubMed,no data found,,,"Tested in Tobacco W38 (WT) plants; infiltration of monocotyledonous plants like maize, oat and bosse showed no necrotic lesions",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 784,PHI:664,UniProt,Q9SPD4,GenBank,AAD53944,,,,PaNie,,,,,,,65070,Pythium aphanidermatum,,,,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: direct injection,,SK,SH,11706166,PubMed,no data found,,,"Tested in Arabidopsis Col-O (WT) plants; infiltration of monocotyledonous plants like maize, oat and bosse showed no necrotic lesions",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 785,PHI:664,UniProt,Q9SPD4,GenBank,AAD53944,,,,PaNie,,,,,,,65070,Pythium aphanidermatum,,,,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: direct injection,,SK,SH,11706166,PubMed,no data found,,,"infiltration of monocotyledonous plants like maize, oat and bosse showed no necrotic lesions",,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 786,PHI:665,UniProt,Q94FS7,EMBL,AAK63068,,,,PcF,,,,,,,29920,Phytophthora cactorum,,P381,root rot,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: direct injection,,SK,SH,11262411,PubMed,10.1074/jbc.M101377200,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 787,PHI:665,UniProt,Q94FS7,EMBL,AAK63068,,,,PcF,,,,,,,29920,Phytophthora cactorum,,P381,root rot,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: direct injection,,SK,SH,11262411,PubMed,10.1074/jbc.M101377200,,,,,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 788,PHI:666,UniProt,Q9AT28,EMBL,AAK19753,,,,NPP1,,,,,,,4792,Phytophthora nicotianae,,1828,buckeye rot (potato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: direct injection,,SK,SH; KHK,12410815,PubMed,no data found,,,infiltration of monocotyledonous plants like maize or barley showed no necrotic lesions. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',,,,,PHI-base Vers.3.3,2007-05-04,RRes,,,,,,,,,,,,,
,,Record 789,PHI:666,UniProt,Q9AT28,EMBL,AAK19753,,,,NPP1,,,,,,,4792,Phytophthora nicotianae,,1828,buckeye rot (potato),eudicots,4043,Petroselinum crispum (related: parsley) (non-host bioassay),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: direct injection,,SK,SH; KHK,12410815,PubMed,no data found,,,infiltration of monocotyledonous plants like maize or barley showed no necrotic lesions; treatment of parsley cells stimulated ethylene biosynthesis. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 790,PHI:666,UniProt,Q9AT28,EMBL,AAK19753,,,,NPP1,,,,,,,4792,Phytophthora nicotianae,,1828,buckeye rot (potato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector protein,"GO:0044416, IMP",GO,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: direct injection,,SK,SH; KHK,12410815,PubMed,no data found,,,infiltration of monocotyledonous plants like maize or barley showed no necrotic lesions. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 791,PHI:667,UniProt,Q6XX21,EMBL,AAP41066,,,H99,FHB1,,,,,,PHI:668,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,flavohemoglobin,"GO:0020027, NAS; GO:0005833, NAS; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,14614821,PubMed,no data found,,,Tested in A/Jcr mice,de Jesus-Berrios et al,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 792,PHI:667,UniProt,Q6XX21,EMBL,AAP41066,,,H99,FHB1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,flavohemoglobin,"GO:0020027, NAS; GO:0005833, NAS; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,wild type,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,14614821,PubMed,no data found,,,Tested in A/Jcr and C57BL/6 (expressing iNOS) mice,de Jesus-Berrios et al,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 793,PHI:667,UniProt,Q6XX21,EMBL,AAP41066,,,H99,FHB1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,flavohemoglobin,"GO:0020027, NAS; GO:0005833",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,14614821,PubMed,no data found,,,Tested in C57BL/6 (iNOS -/-) mice,de Jesus-Berrios et al,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 794,PHI:667,UniProt,Q6XX21,EMBL,AAP41066,,,H99,FHB1,,,,,,PHI:422,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,flavohemoglobin,"GO:0020027, NAS; GO:0005833, NAS; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,14614821,PubMed,no data found,,,Tested in A/Jcr mice,de Jesus-Berrios et al,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 795,PHI:668,UniProt,Q6XVN4,EMBL,AAP41027,,,H99,GNO1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,GSNO reductase,"GO:0042959, NAS",GO,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,AI,SH; KHK,14614821,PubMed,no data found,,,Tested in A/Jcr mice,de Jesus-Berrios et al,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 796,PHI:668,UniProt,Q6XVN4,EMBL,AAP41027,,,H99,GNO1,,,,,,PHI:422,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,GSNO reductase,"GO:0042959, NAS; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,14614821,PubMed,no data found,,,Tested in A/Jcr mice,de Jesus-Berrios et al,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 797,PHI:668,UniProt,Q6XVN4,EMBL,AAP41027,,,H99,GNO1,,,,,,PHI:667,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,GSNO reductase,"GO:0042959, NAS; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,14614821,PubMed,no data found,,,Tested in A/Jcr mice; Significantly more attenuated for virulence than the fhb1 and gno1 single mutants,de Jesus-Berrios et al,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 798,PHI:669,UniProt,Q07080,EMBL,AAG25675,,,JEC21,MFalpha1,,,,,,PHI:670; PHI:671,5207,Cryptococcus neoformans,214684,JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,pheromone (MFalpha),"GO:0000772, NAS; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,12455985,PubMed,10.1128/EC.1.3.366-377.2002,,,Tested in DBA mice; MFalpha pheromone modestly contributes to but is not essential for virulence,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 799,PHI:670,UniProt,Q07080,EMBL,AAL58092,,,JEC21,MFalpha2,,,,,,PHI:669; PHI:671,5207,Cryptococcus neoformans,214684,JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,pheromone (MFalpha),"GO:0000772, NAS; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,12455985,PubMed,10.1128/EC.1.3.366-377.2002,,,Tested in DBA mice; MFalpha pheromone modestly contributes to but is not essential for virulence,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 800,PHI:671,UniProt,Q8X122,EMBL,AAL58091,,,JEC21,MFalpha3,,,,,,PHI:669; PHI:670,5207,Cryptococcus neoformans,214684,JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,pheromone (MFalpha),"GO:0000772, NAS; GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,12455985,PubMed,10.1128/EC.1.3.366-377.2002,,,Tested in DBA mice; MFalpha pheromone modestly contributes to but is not essential for virulence,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 801,PHI:672,UniProt,P0CM56,EMBL,AAL35099,,,,CAS1,,,,,,,5207,Cryptococcus neoformans,192011,serotype D strain NE167-170,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,capsule polysaccharide biosynthesis,"GO:0045227, NAS; GO:0042603, NAS; GO:0051701, IMP; GO:0016413, NAS",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,11703667,PubMed,no data found,,,Tested in BALB/c mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 802,PHI:673,UniProt,Q30E79,EMBL,AAZ30050,,,H99,Can1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,carbonic anhydrase,"GO:0004089, NAS; GO:0009405, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,16303560,PubMed,10.1016/j.cub.2005.09.047,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 803,PHI:674,UniProt,Q3I4V7,EMBL,AAZ30051,,,H99,Can2,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,carbonic anhydrase,"GO:0004089, NAS",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,16303560,PubMed,10.1016/j.cub.2005.09.047,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 804,PHI:674,UniProt,Q3I4V7,EMBL,AAZ30051,,,H99,Can2,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,carbonic anhydrase,"GO:0004089, NAS; GO:0009405, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,16303560,PubMed,10.1016/j.cub.2005.09.047,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 805,PHI:675,UniProt,Q5KB00,EMBL,AAW45289,,,JEC21,ROM2,,,,,,,5207,Cryptococcus neoformans,192011,KN99α,cryptococcosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,,"GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,16299318,PubMed,10.1128/IAI.73.12.8219-8225.2005,,,Tested in ICR/CD1 mice; homologous to S.cerevisae ROM2,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 806,PHI:675,UniProt,Q5KB00,EMBL,AAW45289,,,JEC21,ROM2,,,,,,,5207,Cryptococcus neoformans,192011,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,,"GO:0051701, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,16299318,PubMed,10.1128/IAI.73.12.8219-8225.2005,,,Tested in ICR/CD1 mice; homologous to S.cerevisae ROM2,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 807,PHI:676,UniProt,Q9UV59,EMBL,AAN75173,,,H99,STE20alpha,,,,,,PHI:677,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0004672, NAS",GO,,lethal,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,12455960,PubMed,10.1128/EC.1.2.257-272.2002,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 808,PHI:676,UniProt,Q9UV59,EMBL,AAN75173,,,H99,STE20alpha,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,protein kinase,"GO:0004672, NAS; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,12455960,PubMed,10.1128/EC.1.2.257-272.2002,,,,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 809,PHI:676,UniProt,Q9UV59,EMBL,AAN75173,,,H99,STE20alpha,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0004672, NAS; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,12455960,PubMed,10.1128/EC.1.2.257-272.2002,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 810,PHI:677,UniProt,Q8X1F1,EMBL,AAL58841,,,,PAK1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0004672, NAS; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,12455960,PubMed,10.1128/EC.1.2.257-272.2002,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 811,PHI:677,UniProt,Q8X1F1,EMBL,AAL58841,,,,PAK1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,protein kinase,"GO:0004672, NAS; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,SH; KHK,12455960,PubMed,10.1128/EC.1.2.257-272.2002,,,,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 812,PHI:678,UniProt,Q9HEW5,EMBL,AAG48305,,,JEC21,STE20alpha,,,,,,,5207,Cryptococcus neoformans,214684,serotype D strain JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0004672, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,12455960,PubMed,10.1128/EC.1.2.257-272.2002,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 813,PHI:678,UniProt,Q9HEW5,EMBL,AAG48305,,,JEC21,STE20alpha,,,,,,PHI:680,5207,Cryptococcus neoformans,214684,serotype D strain JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0004672, NAS",GO,,lethal,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,12455960,PubMed,10.1128/EC.1.2.257-272.2002,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 814,PHI:679,UniProt,Q9HEW2,EMBL,AAG48308,,,JEC20,STE20a,,,,,,,5207,Cryptococcus neoformans,40410,serotype D strain JEC20,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0004672, NAS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,12455960,PubMed,10.1128/EC.1.2.257-272.2002,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 815,PHI:679,UniProt,Q9HEW2,EMBL,AAG48308,,,JEC20,STE20a,,,,,,PHI:680,5207,Cryptococcus neoformans,40410,serotype D strain JEC20,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0004672, NAS",GO,,lethal,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,12455960,PubMed,10.1128/EC.1.2.257-272.2002,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 816,PHI:680,UniProt,Q8X1F0,EMBL,AAL58842,,,,PAK1,,,,,,,5207,Cryptococcus neoformans,214684,serotype D strain JEC20; serotype D strain JEC21,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,protein kinase,"GO:0004672, NAS; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,12455960,PubMed,10.1128/EC.1.2.257-272.2002,,,Tested in A/Jcr mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 817,PHI:681,,no data found,EMBL,ABF18931,,,JEC21,VPS41,,,,,,,5207,Cryptococcus neoformans,,H99FOA19,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,regulation of starvation response,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AI,AB; KHK,16879414,PubMed,10.1111/j.1365-2958.2006.05299.x,,prw@uic.edu,Failure to undergo G2 arrest. Could not survive in macrophages,Liu et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 818,PHI:683,UniProt,Q197G0,EMBL,ABF69301,,,,NRG1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,cAMP-regulated transcription factor,"GO:0009405, IMP",GO,cAMP signalling,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,AI,AB; KHK,16835458,PubMed,10.1128/EC.00145-06,,andrew.alspaugh@duke.edu,Delayed capsule formation and mating. Increased cell aggregation,Cramer et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 819,PHI:685,UniProt,Q12634,,,,,,BUF,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,,"GO:0009405, IMP; GO:0044409, IMP",GO,,loss of pathogenicity,,,yes,,,,,,,,,,,,,,gene disruption,,AS,AB; MU,15457264,PubMed,10.1038/nature02880,,annie.osbourn@sainsbury-laboratory.ac.uk,Unable to penetrate leaves but forms lesions on barley roots,Sesma and Osbourn,2004,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 820,PHI:686,,no data found,EMBL,EAA52507,,,,MST50,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,adaptor protein in PMK1 cascade,"GO:0009405, IMP; GO:0044409, IMP; GO:0044412, IMP",GO,,loss of pathogenicity,,,yes,yes,,,,no,,,,,,,,,gene deletion; gene complementation,,AS,AB; MU,17056708,PubMed,10.1105/tpc.105.038422,,jinrong@purdue.edu,No appressoria formation,Park et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 821,PHI:687,UniProt,P0CS95,EMBL,AAA33076,,,,URA5,,,,,,,5207,Cryptococcus neoformans,40410,B-3501,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,orotidine monophosphate pyrophosphorylase,"GO:0004645, NAS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,AI,SH; KHK,1541525,PubMed,no data found,,,Tested in BALB/c mice,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 822,PHI:690,UniProt,Q92246,EMBL,AAC49521,,,Guy11,PMK1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),,,,,MAP kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AS,AB; MU,11277427,PubMed,10.1094/MPMI.2001.14.3.300,,annie.osbourn@bbsrc.ac.uk,Unable to cause lesions on roots,Dufresne and Osbourn,2001,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 823,PHI:690,UniProt,Q92246,EMBL,AAC49521,,,Guy11,PMK1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,MAP kinase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,AS,AB; MU,11277427,PubMed,10.1094/MPMI.2001.14.3.300,,annie.osbourn@bbsrc.ac.uk,Unable to cause lesions on roots,Dufresne and Osbourn,2001,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 824,PHI:693,UniProt,Q58FH5,EMBL,AAX55972,,,H99,GCS1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,glucosylceramide synthase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,AI,AB; KHK,16741577,PubMed,10.1172/JCI27890,,delpoeta@musc.edu,,Rittershaus et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 825,PHI:694,UniProt,Q6TGK1,EMBL,AAS92520,,,,STE12alpha / NOG2,,,,,,,552467,Cryptococcus bacillisporus,1441719,NIH 444,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,,transcription factor,"GO:0009405, IMP; GO:0044412, IMP",GO,,reduced virulence,,,,yes,,,,,,,,,,,,,gene disruption; gene complementation,,AI,AB,16825451,PubMed,10.2134/jeq2006.0008,,vishnu@wadsworth.org,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,Ren et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 826,PHI:695,UniProt,Q8J0U4,EMBL,AAM33130,,,M1,SP1,,,,,,,5022,Leptosphaeria maculans,,M1,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,secreted protein 1,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,BH,SH; AC,20569355,PubMed,10.1046/j.1364-3703.2002.00144.x,Wilson et al. (2002) MOLECULAR PLANT PATHOLOGY 3 (6):487-493,bhowlett@unimelb.edu.au,,Wilson et al.,2002,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 827,PHI:696,UniProt,Q8NJR9,EMBL,AAM92143,,,M1,NTH1,,,,,,,5022,Leptosphaeria maculans,,M1,Phoma stem canker,eudicots,3707,Brassica juncea (related: brown mustard),,,,,neutral trehelase,,,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,BH,SH; AC,,Not in PubMed,10.1016/S0885-5765(03)00074-2,Idnurm et al. (2003) PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY 62:305-313,bhowlett@unimelb.edu.au,Tested in B. juncea cv. Stoke,Idnurm et al.,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 828,PHI:696,UniProt,Q8NJR9,EMBL,AAM92143,,,M1,NTH1,,,,,,,5022,Leptosphaeria maculans,,M1,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,neutral trehelase,,,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,BH,SH; AC,,Not in PubMed,10.1016/S0885-5765(03)00074-2,Idnurm et al. (2003) PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY 62:305-313,bhowlett@unimelb.edu.au,Tested in B. napus cv. Westar,Idnurm et al.,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 829,PHI:697,UniProt,Q8NJS2,EMBL,AAM81358,,,M1,ugt51E1,,,,,,,5022,Leptosphaeria maculans,,M1,Phoma stem canker,eudicots,3707,Brassica juncea (related: brown mustard),,,,,UDP-glucose: sterol glucosyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,BH,SH; AC,,Not in PubMed,10.1016/S0885-5765(03)00074-2,Idnurm et al. (2003) PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY 62:305-313,bhowlett@unimelb.edu.au,Tested in B. juncea cv. Stoke,Idnurm et al.,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 830,PHI:697,UniProt,Q8NJS2,EMBL,AAM81358,,,M1,ugt51E1,,,,,,,5022,Leptosphaeria maculans,,M1,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,UDP-glucose: sterol glucosyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,BH,SH; AC,,Not in PubMed,10.1016/S0885-5765(03)00074-2,Idnurm et al. (2003) PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY 62:305-313,bhowlett@unimelb.edu.au,Tested in B. napus cv. Westar,Idnurm et al.,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 831,PHI:698,UniProt,P01555,EMBL,AAF94614,,,N16961,CtxA,chromosome 1,,,,,PHI:699,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,primates,9606,Homo sapiens (related: human),,,,,Cholera toxin (CT),"GO:0003950, IMP; GO:0006471, IMP; GO:0031640, IMP; GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,HH,HH,3335402,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 832,PHI:699,UniProt,P01556,EMBL,AAF94613,,,N16961,CtxB,chromosome 1,,,,,PHI:698,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,primates,9606,Homo sapiens (related: human),,,,,Cholera toxin (CT),"GO:0006471, IMP; GO:0009405, IMP; GO:0031640, IMP; GO:0046812, IDA",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,HH,HH,3335402,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 833,PHI:700,UniProt,Q60153,EMBL,AAF93991,,,N16961,TcpA,chromosome 1,,,,,,666,Vibrio cholerae,345073,race 5,cholera,primates,9606,Homo sapiens (related: human),,,,,toxin-coregulated pilus (TCP)-an intestinal colonization factor,"GO:0005198, ISS; GO:0009289, ISS; GO:0009405, ISS; GO:0030030, ISS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,HH,HH,2902187,PubMed,10.1084/jem.168.4.1487,,,,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 834,PHI:701,UniProt,P15795,EMBL,AAF94145,,,N16961,ToxR,chromosome 1,,,,,,666,Vibrio cholerae,45888,race 5,cholera,rodents,10090,Mus musculus (related: house mouse),,,,,controls expression of CT and TCP,"GO:0006355, ISS; GO:0009405, ISS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,HH,HH,7903285,PubMed,no data found,,,CD-1 mouse,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 835,PHI:702,UniProt,O68839,EMBL,AAC63504,,,C6706str2,VcpD,chromosome 1,,,,,,666,Vibrio cholerae,345073,O395,cholera,rodents,10090,Mus musculus (related: house mouse),,,,,required for philus assembly and CT secretion,"GO:0009405, ISS; GO:0009306, ISS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,HH,HH,9781884,PubMed,no data found,,,CD-1 mouse,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 836,PHI:703,UniProt,Q06951,EMBL,AAF93418,,,N16961,RfbB,chromosome 1,,,,,,666,Vibrio cholerae,345073,O395,cholera,rodents,10090,Mus musculus (related: house mouse),,,,,O-antigen biosynthesis,"GO:0004615, ISS; GO:0005975, ISS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,HH,HH,9916119,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 837,PHI:704,UniProt,Q9KV11,EMBL,AAF93520,,,N16961,Hfq,chromosome 1,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),,,,,RNA binding protein that modulates gene expression post-transcription,"GO:0003723, ISS; GO:0006378, ISS; GO:0030423, ISS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,HH,HH,15225327,PubMed,10.1111/j.1365-2958.2004.04142.x,,,CD-1 mouse,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 838,PHI:706,UniProt,P38441,EMBL,AAF94616,,,N16961,Ace,chromosome 1,,,,,,666,Vibrio cholerae,686,El Tor Ogawa,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,,CTXF morphogenesis,"GO:0006820, ISS; GO:0009405, ISS; GO:0031640, ISS; GO:0051049, ISS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,HH; HJC,HH; AC,8389476,PubMed,10.1073/pnas.90.11.5267,Trucksis et al. (1993) PNAS 90(11): 5267-5271,,Ileal tissue from rabbit,Trucksis et al.,1993,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 839,PHI:707,UniProt,P0C6Q6,EMBL,AAF93799,,,N16961,OmpU,chromosome 1,,,,,,666,Vibrio cholerae,345073,O395,cholera,rodents,10090,Mus musculus (related: house mouse),,,,,outer membrane protein,"GO:0003674, ND; GO:0008150, ND; GO:0009279, ISS",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,HH,HH,11371530,PubMed,10.1128/JB.183.12.3652-3662.2001,,,CD-1 mouse,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 840,PHI:708,UniProt,Q9KT84,EMBL,AAF94180,,,N16961,LuxO,chromosome 1,,,,,,666,Vibrio cholerae,686,El Tor,cholera,rodents,10090,Mus musculus (related: house mouse),,,,,quorum-sensing regulator,"GO:0000156, ISS; GO:0000160, ISS; GO:0003700, ISS; GO:0006355, ISS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,HH,HH,11854465,PubMed,10.1073/pnas.052694299,,,CD-1 mouse,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 841,PHI:709,UniProt,Q9S3S3,EMBL,AAD50301,,,569B,RelA,chromosome 1,,,,,,666,Vibrio cholerae,686,El Tor,cholera,rodents,10090,Mus musculus (related: house mouse),,,,,GTP pyrophosphokinase,"GO:0009267, ISS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,HH,HH,12896985,PubMed,10.1128/jb.185.16.4672-4682.2003,,,,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 842,PHI:710,UniProt,Q9F5R1,EMBL,AAK57702,,,SCE263,ToxT,chromosome 1,,,,,,666,Vibrio cholerae,345073,race 5,cholera,rodents,10090,Mus musculus (related: house mouse),,,,,virulence transcriptional activator,"GO:0003700, ISS; GO:0006355, ISS; GO:0009405, ISS",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,HH,HH,9044266,PubMed,no data found,,,,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 843,PHI:711,UniProt,Q9X399,EMBL,AAD31382,,,O395,AphA,chromosome 1,,,,,,666,Vibrio cholerae,345073,O395,cholera,rodents,10090,Mus musculus (related: house mouse),,,,,virulence activator,"GO:0008150, ND",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,HH,HH,11489126,PubMed,no data found,,,CD-1 mouse,,,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 844,PHI:712,UniProt,I1RF62,Broad,FGSG_02328,,,,GIP1,,,,,,,5518,Fusarium graminearum,,SCK04,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,putative laccase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene mutation,,,AB,15811992,PubMed,10.1128/AEM.71.4.1701-1708.2005,,lee2443@snu.ac.kr,Pigmentation mutant; mutation (REMI),Kim et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 845,PHI:713,UniProt,Q2VLJ3,EMBL,ABB90282,,,PH-1,PKS13 (ZEA2),,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,zearalenone synthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB,16262793,PubMed,10.1111/j.1365-2958.2005.04884.x,,lee2443@snu.ac.kr,,Kim et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 846,PHI:713,UniProt,Q2VLJ3,EMBL,ABB90282,,,PH-1,PKS13 (ZEA2),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,zearalenone synthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 847,PHI:714,UniProt,Q2VLJ2,EMBL,ABB90283,,,PH-1,PKS4 (ZEA1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,zearalenone synthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 848,PHI:714,UniProt,Q2VLJ2,EMBL,ABB90283,,,PH-1,PKS4 (ZEA1),,,,,,,5518,Fusarium graminearum,,1104-14,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,zearalenone synthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16751498,PubMed,10.1128/AEM.00963-05,,erik.lysoe@bioforsk.no,Root infection assay,Lysoe et al,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 849,PHI:714,UniProt,Q2VLJ2,EMBL,ABB90283,,,PH-1,PKS4 (ZEA1),,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,zearalenone synthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB,16262793,PubMed,10.1111/j.1365-2958.2005.04884.x,,lee2443@snu.ac.kr,,Kim et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 850,PHI:715,UniProt,Q2VLJ0,Broad,FG02398,,,PH-1,ZEB2,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,zearalenone synthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB,16262793,PubMed,10.1111/j.1365-2958.2005.04884.x,,lee2443@snu.ac.kr,,Kim et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 851,PHI:716,UniProt,Q2VLJ1,EMBL,ABB90284,,,PH-1,ZEB1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,zearalenone synthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB,16262793,PubMed,10.1111/j.1365-2958.2005.04884.x,,lee2443@snu.ac.kr,,Kim et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 852,PHI:717,UniProt,A0A098DM59,EMBL,FGRAMPH1_01T15421,,,,PLSP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 853,PHI:718,UniProt,Q6RKH4,EMBL,AAS57291,,,GZ-3639,PKS6,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 854,PHI:719,UniProt,I1RUB2,Broad,FGSG_07798,,,,GzFUS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,fusarin C synthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 855,PHI:720,UniProt,I1RF58,Broad,FGSG_02324,,,,AUR1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,aurofusarin synthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 856,PHI:721,UniProt,I1RJE8,Broad,FGSG_03964,,,,GRS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 857,PHI:722,UniProt,A0A098DQH7,EMBL,FGRAMPH1_01T27727,,,,PGL1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,black perithecial pigment synthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 858,PHI:723,UniProt,I1RHS7,Broad,FGSG_03340,,,GZ-3639,PKS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 859,PHI:724,UniProt,I1RSU2,Broad,FGSG_07226,,,GZ-3639,PKS9,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 860,PHI:725,UniProt,Q6RKG9,EMBL,AAS57295,,,GZ-3639,PKS11,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 861,PHI:726,UniProt,Q6RKH3,EMBL,AAS57292,,,GZ-3639,PKS7,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 862,PHI:727,UniProt,I1RHS7,Broad,FGSG_03340,,,,PKS17,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 863,PHI:728,UniProt,Q6RKH5,EMBL,AAS57290,,,GZ-3639,PKS5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 864,PHI:729,UniProt,Q6RKH8,EMBL,AAS57287,,,GZ-3639,PKS2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 865,PHI:730,UniProt,I1RSU2,Broad,FGSG_07226,,,,KSA1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,16278459,PubMed,10.1128/EC.4.11.1926-1933.2005,,trail@msu.edu,,Gaffoor et al,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 866,PHI:731,UniProt,Q2TJF8,EMBL,AAX55652,,,,FSR1,,,,,,,5127,Fusarium fujikuroi,,7600,foolish seedling,monocots,4577,Zea mays (related: maize),,,,,putative signalling scaffold protein,GO:0009405; GO:0044409; GO:0000909,GO,,loss of pathogenicity,,,yes,,,,no perithecia formation,,,,,,,,,,gene disruption; complementation; other evidence,,,AB,16838785,PubMed,10.1094/MPMI-19-0725,,wbshim@tamu.edu,Could not produce perithecia,Shim et al,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 867,PHI:731,,no data found,EMBL,EAA68366,,,,FgFSR1,,,,,,,5518,Fusarium graminearum,229533,Z03639,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,putative signalling scaffold protein,GO:0009405; GO:0000909,GO,,reduced virulence,,,,,,,no perithecia formation,,,,,,,,,,gene deletion; gene complementation,,,AB; AC,16838785,PubMed,10.1094/MPMI-19-0725,Shim et al. (2006) Mol Plant Microbe Interact 19(7): 725-733,wbshim@tamu.edu,Could not produce perithecia; striatin-like protein,Shim et al,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 868,PHI:733,UniProt,I1REK5,Broad,FGSG_02095,,,,FBP1,,,,,,,5518,Fusarium graminearum,229533,Z03643,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,F-box protein,GO:0009405; GO:0000909,GO,,reduced virulence,,,,,,,no perithecia formation,aberrant (some impairment),,,,,,,,,gene deletion; gene complementation,,,AB; AC,17302802,PubMed,10.1111/j.1365-2958.2006.05557.x,Han et al. (2007) Molecular Microbiology 63(3): 768-779,lee2443@snu.ac.kr,"Hyphal growth reduced, no perithecia produced",Han et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 869,PHI:734,UniProt,Q0WXM3,EMBL,BAE98264,,,Mel02010,FOW2,,,,,,,5507,Fusarium oxysporum,,f. sp. melonis race 2 strain Mel02010,vascular wilt,eudicots,3656,Cucumis melo (related: muskmelon),,,,,putative Zn finger transcription factor,GO:0009405; GO:0044409; GO:0044412,GO,,loss of pathogenicity,,,yes,yes,,,,,,,,,,,,,gene disruption; gene complementation,,,AB,17302801,PubMed,10.1111/j.1365-2958.2006.05554.x,,ttsuge@agr.nagoya-u.ac.jp,,Imazaki et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 870,PHI:734,UniProt,Q0WXM3,EMBL,BAE98264,,,Mel02010,FOW2,,,,,,,5507,Fusarium oxysporum,,CK3-1,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,putative Zn finger transcription factor,GO:0009405,GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,17302801,PubMed,10.1111/j.1365-2958.2006.05554.x,,ttsuge@agr.nagoya-u.ac.jp,,Imazaki et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 871,PHI:736,UniProt,Q6R3Q3,EMBL,AAS20192,,,ATCC 34622,AMK1,,,,,,,29001,Alternaria brassicicola,29001,ATCC 96866,black spot,eudicots,3712,Brassica oleracea (no common name found),,,,,Fus3/Kss1 MAP kinase homologue,GO:0009405; GO:0044409,GO,,loss of pathogenicity,,,yes,,,defective,,,,,,,,,,,gene disruption; gene complementation,,,AB,17280842,PubMed,10.1016/j.fgb.2006.11.015,,lawrence@vbi.vt.edu,Could infect wounded plants or when inoculated with nutrient supplements,Cho et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 872,PHI:736,UniProt,Q6R3Q3,EMBL,AAS20192,,,ATCC 34622,AMK1,,,,,,,29001,Alternaria brassicicola,29001,ATCC 96866,black spot,eudicots,3708,Brassica napus (related: rape),,,,,Fus3/Kss1 MAP kinase homologue,GO:0009405; GO:0044409,GO,,loss of pathogenicity,,,yes,,,defective,,,,,,,,,,,gene disruption; gene complementation,,,AB,17280842,PubMed,10.1016/j.fgb.2006.11.015,,lawrence@vbi.vt.edu,Could infect wounded plants or when inoculated with nutrient supplements,Cho et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 873,PHI:736,UniProt,Q6R3Q3,EMBL,AAS20192,,,ATCC 34622,AMK1,,,,,,,29001,Alternaria brassicicola,29001,ATCC 96866,black spot,eudicots,52824,Brassica carinata (related: ethiopian mustard),,,,,Fus3/Kss1 MAP kinase homologue,GO:0009405; GO:0044409,GO,,loss of pathogenicity,,,yes,,,defective,,,,,,,,,,,gene disruption; gene complementation,,,AB,17280842,PubMed,10.1016/j.fgb.2006.11.015,,lawrence@vbi.vt.edu,Could infect wounded plants or when inoculated with nutrient supplements,Cho et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 874,PHI:736,UniProt,Q6R3Q3,EMBL,AAS20192,,,ATCC 34622,AMK1,,,,,,,29001,Alternaria brassicicola,29001,ATCC 96866,black spot,eudicots,3707,Brassica juncea (related: brown mustard),,,,,Fus3/Kss1 MAP kinase homologue,GO:0009405; GO:0044409,GO,,loss of pathogenicity,,,yes,,,defective,,,,,,,,,,,gene disruption; gene complementation,,,AB,17280842,PubMed,10.1016/j.fgb.2006.11.015,,lawrence@vbi.vt.edu,Could infect wounded plants or when inoculated with nutrient supplements,Cho et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 875,PHI:737,UniProt,A0ST42,EMBL,ABK64181,,,,CTB4,,,,,,,29003,Cercospora nicotianae,29003,14,frog-eye leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,putative MFS transporter,GO:0009405,GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,AB,17250832,PubMed,10.1016/j.febslet.2007.01.011,,krchung@ufl.edu,Reduced cercosporin accumulation,Choquer et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 876,PHI:739,UniProt,Q4KPC8,EMBL,AAX49357,,,70-15,SSM1,,,,,,,318829,Magnaporthe oryzae,242507,70-15; Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,ferricrocin synthetase,GO:0009405; GO:0044409,GO,,reduced virulence,,,yes,,,,,,,,,,,,,,gene disruption,,,AB,20507488,PubMed,10.1111/j.1364-3703.2007.00380.x,,eisfeld@ibwf.de,,Hof et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 877,PHI:743,UniProt,I1RE63,Broad,FGSG_01939,,,,ARG2,,,,,,,5518,Fusarium graminearum,,SCK04,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,acetylglutamate synthase,GO:0009405,GO,,reduced virulence,,,,,,defective,defective,defective,,,,,,,,,gene deletion; gene complementation,,,AB,17146619,PubMed,10.1007/s00294-006-0110-1,,lee2443@snu.ac.kr,complementation of REMI disruption,Kim et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 878,PHI:744,UniProt,I1RFM6,Broad,FGSG_02506,,,,ADE5,,,,,,,5518,Fusarium graminearum,,SCK04,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,phosphoribosylamine-glycine ligase,GO:0009405,GO,,reduced virulence,,,,,,defective,defective,defective on minimal media,,,,,,,,,gene deletion; gene complementation,,,AB,17146619,PubMed,10.1007/s00294-006-0110-1,,lee2443@snu.ac.kr,complementation of REMI disruption,Kim et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 879,PHI:746,,no data found,Broad,um10115,,,521,um10115,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 1A of secreted proteins; There are three genes predicted in cluster 1A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 880,PHI:747,UniProt,Q4PHG8,Broad,um00445,,,521,um00445,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 1A of secreted proteins; There are three genes predicted in cluster 1A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 881,PHI:748,UniProt,Q4PHG7,Broad,um00446,,,521,um00446,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,probable beta-glucosidase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 1A of secreted proteins; There are three genes predicted in cluster 1A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 882,PHI:749,UniProt,G3CJZ9,Broad,um01234,,,521,um01234,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,putative protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2A of secreted proteins. Incidence and size of tumours increased. Eight genes predicted in cluster 2A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 883,PHI:750,UniProt,G3CK30,Broad,um01235,,,521,um01235,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2A of secreted proteins. Incidence and size of tumours increased. Eight genes predicted in cluster 2A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 884,PHI:751,UniProt,G3CJZ1,Broad,um01236,,,521,um01236,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2A of secreted proteins. Incidence and size of tumours increased. Eight genes predicted in cluster 2A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 885,PHI:752,UniProt,G3CK22,Broad,um01237,,,521,um01237,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2A of secreted proteins. Incidence and size of tumours increased. Eight genes predicted in cluster 2A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 886,PHI:753,UniProt,G3CK43,Broad,um01238,,,521,um01238,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2A of secreted proteins. Incidence and size of tumours increased. Eight genes predicted in cluster 2A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 887,PHI:754,UniProt,G3CK14,Broad,um01239,,,521,um01239,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2A of secreted proteins. Incidence and size of tumours increased. Eight genes predicted in cluster 2A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 888,PHI:755,UniProt,G3CJY5,Broad,um01240,,,521,um01240,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2A of secreted proteins. Incidence and size of tumours increased. Eight genes predicted in cluster 2A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 889,PHI:756,UniProt,G3CK16,Broad,um01241,,,521,um01241,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2A of secreted proteins. Incidence and size of tumours increased. Eight genes predicted in cluster 2A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 890,PHI:757,UniProt,Q4PF16,Broad,um01297,,,522,um01297,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2B of secreted proteins. Six genes predicted in cluster 2B.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 891,PHI:758,UniProt,Q09QS3,EMBL,ABH03483,,,CC148,Avra10,,,,,,,34373,Blumeria graminis,62688,CC148,powdery mildew,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,effector protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,KHK,16905653,PubMed,10.1105/tpc.106.043307,,christopher.ridout@bbsrc.ac.uk,Activates Mla10 mediated resistance. Seven different types of experimental evidence provided.,Ridout et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 892,PHI:759,UniProt,Q09QS2,EMBL,ABH03482,,,CC148,Avrk1,,,,,,,34373,Blumeria graminis,62688,CC148,powdery mildew,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,effector protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,other evidence,,,KHK,16905653,PubMed,10.1105/tpc.106.043307,,,Activates Mlk1 mediated resistance. Seven different types of experimental evidence provided.,Ridout et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 893,PHI:760,UniProt,Q01905,EMBL,AAB49807,,,88069,INF1,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight,eudicots,856898,Solanum huancabambense (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,,KHK,20507464,PubMed,10.1111/j.1364-3703.2006.00355.X,,vivianne.vleeshouwers@wur.nl,,Vleeshouwers et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 894,PHI:760,UniProt,Q01905,EMBL,AAB49807,,,88069,INF1,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight,eudicots,73574,Solanum microdontum (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,,KHK,20507464,PubMed,10.1111/j.1364-3703.2006.00355.X,,vivianne.vleeshouwers@wur.nl,,Vleeshouwers et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 895,PHI:762,UniProt,O42718,EMBL,AAU10320,,,88069,INF2A,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight,eudicots,856898,Solanum huancabambense (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,,KHK,20507464,PubMed,10.1111/j.1364-3703.2006.00355.X,,vivianne.vleeshouwers@wur.nl,,Vleeshouwers et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 896,PHI:762,UniProt,O42718,EMBL,AAU10320,,,88069,INF2A,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight,eudicots,73574,Solanum microdontum (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,,KHK,20507464,PubMed,10.1111/j.1364-3703.2006.00355.X,,vivianne.vleeshouwers@wur.nl,,Vleeshouwers et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 897,PHI:764,UniProt,O42719,EMBL,AAB94815,,,88069,INF2B,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight,eudicots,856898,Solanum huancabambense (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,,KHK,20507464,PubMed,10.1111/j.1364-3703.2006.00355.X,,vivianne.vleeshouwers@wur.nl,,Vleeshouwers et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 898,PHI:764,UniProt,O42719,EMBL,AAB94815,,,88069,INF2B,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight,eudicots,73574,Solanum microdontum (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,necrosis,functional test in host: transient expression,,,KHK,20507464,PubMed,10.1111/j.1364-3703.2006.00355.X,,vivianne.vleeshouwers@wur.nl,,Vleeshouwers et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 899,PHI:768,UniProt,Q51MW4,EMBL,EHA48293,,,Guy11,ATG8,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,loss of pathogenicity,,yes,,,,defective,,,,,,,,,,,gene deletion; gene complementation,,,KHK,16645096,PubMed,10.1126/science.1124550,,n.j.talbot@exeter.ac.uk,Atg8 mutant effective in autophagic cell death,Veneault-Fourrey et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 900,PHI:769,UniProt,Q96VL0,EMBL,CAC50073,,,T5,CPSOD1,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,superoxide dismutase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,MU; AC,20569304,PubMed,10.1046/j.1464-6722.2001.00088.x,Moore et al. (2002) Molecular Plant Pathology 3:9-22,tudzyns@uni-muenster.de,,Moore et al.,2002,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 901,PHI:770,UniProt,Q00580,EMBL,AAA67706,,,EP155,CPG2,,,,,,,5116,Cryphonectria parasitica,660469,EP155,blight (chestnut),eudicots,134033,Castanea dentata (related: american chestnut),,,,,G alpha protein subunit,"GO:0009405, IMP",GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,KHK,11038529,PubMed,10.1073/pnas.93.24.14122,,,,Gao and Nuss,1996,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 902,PHI:772,UniProt,G4MSX7,Broad,MGG_01481,,,70-15,MGG_01481,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 903,PHI:773,UniProt,G4MRZ0,Broad,MGG_11899,,,70-15,MGG_11899,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 904,PHI:774,UniProt,G4MQ72,Broad,MGG_09250,,,70-15,MGG_09250,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 905,PHI:775,UniProt,O42622,Broad,MGG_09471,,,70-15,MGG_09471,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 906,PHI:776,UniProt,G4NF05,Broad,MGG_00692,,,70-15,MGG_00692,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 907,PHI:777,UniProt,G4NDR3,Broad,MGG_00883,,,70-15,MGG_00883,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 908,PHI:778,,no data found,Broad,MGG_04138,,,70-15,MGG_04138,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 909,PHI:779,,no data found,Broad,MGG_11107,,,70-15,MGG_11107,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 910,PHI:780,UniProt,G5EH19,Broad,MGG_02731,,,70-15,MGG_02731,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 911,PHI:781,,no data found,Broad,MGG_00131,,,70-15,MGG_00131,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 912,PHI:782,,no data found,Broad,MGG_02423,,,70-15,MGG_02423,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 913,PHI:783,UniProt,G4NIP2,Broad,MGG_04163,,,70-15,MGG_04163,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 914,PHI:784,UniProt,G4NES9,Broad,MGG_00056,,,70-15,MGG_00056,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene deletion,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 915,PHI:785,UniProt,G4NIS9,Broad,MGG_04128,,,70-15,MGG_04128,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 916,PHI:786,UniProt,G4MSS9,Broad,MGG_04538,,,70-15,MGG_04538,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 917,PHI:787,UniProt,G5EH19,Broad,MGG_02731,,,70-15,MGG_02731,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 918,PHI:788,,no data found,Broad,MGG_11742,,,70-15,MGG_11742,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,predicted protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 919,PHI:789,UniProt,G4NIU3,Broad,MGG_04116,,,70-15,MGG_04116,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 920,PHI:790,UniProt,G4MUI1,Broad,MGG_07259,,,70-15,MGG_07259,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 921,PHI:791,UniProt,G4MRZ0,Broad,MGG_11899,,,70-15,MGG_11899,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 922,PHI:792,UniProt,G4MQ72,Broad,MGG_09250,,,70-15,MGG_09250,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 923,PHI:793,UniProt,G4MKW8,Broad,MGG_13024,,,70-15,MGG_13024,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 924,PHI:794,UniProt,O42622,Broad,MGG_09471,,,70-15,MGG_09471,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,neutral trehalase,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 925,PHI:795,UniProt,G4N8B1,Broad,MGG_03451,,,70-15,MGG_03451,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 926,PHI:796,,no data found,Broad,MGG_02423,,,70-15,MGG_02423,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,"HDEL sequence binding protein, putative",,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 927,PHI:797,UniProt,G4MSX7,Broad,MGG_01481,,,70-15,MGG_01481,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 928,PHI:798,UniProt,G4NHW9,Broad,MGG_12026,,,70-15,MGG_12026,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,predicted protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 929,PHI:799,UniProt,G4N7R4,Broad,MGG_03530,,,70-15,MGG_03530,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 930,PHI:800,UniProt,G4MZS7,Broad,MGG_13324,,,70-15,MGG_13324,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 931,PHI:801,UniProt,G4MRQ6,Broad,MGG_04621,,,70-15,MGG_04621,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 932,PHI:802,UniProt,G4NF05,Broad,MGG_00692,,,70-15,MGG_00692,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 933,PHI:803,UniProt,G4MRP7,Broad,MGG_04629,,,70-15,MGG_04629,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 934,PHI:804,UniProt,G4ML19,Broad,MGG_08628,,,70-15,MGG_08628,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 935,PHI:805,UniProt,G4NEF1,Broad,MGG_00124,,,70-15,MGG_00124,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 936,PHI:806,UniProt,G4NIR9,Broad,MGG_04137,,,70-15,MGG_04137,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 937,PHI:807,UniProt,G4MNG8,Broad,MGG_06951,,,70-15,MGG_06951,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 938,PHI:808,UniProt,G5EH19,Broad,MGG_02731,,,70-15,MGG_02731,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 939,PHI:809,,no data found,Broad,MGG_12373,,,70-15,MGG_12373,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 940,PHI:810,UniProt,G4MRI4,Broad,MGG_02436,,,70-15,MGG_02436,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 941,PHI:811,UniProt,G4MS40,Broad,MGG_10510,,,70-15,MGG_10510,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 942,PHI:812,UniProt,G4NIB5,Broad,MGG_10702,,,70-15,MGG_10702,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 943,PHI:813,,no data found,Broad,MGG_11388,,,70-15,MGG_11388,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,predicted protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 944,PHI:814,,no data found,Broad,MGG_13696,,,70-15,MGG_13696,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,predicted protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 945,PHI:815,UniProt,G4MRB0,Broad,MGG_04685,,,70-15,MGG_04685,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 946,PHI:816,UniProt,G4MRS8,Broad,MGG_04582,,,70-15,MGG_04582,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 947,PHI:817,,no data found,Broad,MGG_12252,,,70-15,MGG_12252,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 948,PHI:818,,no data found,Broad,MGG_11504,,,70-15,MGG_11504,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,predicted protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 949,PHI:819,UniProt,G4MZS1,Broad,MGG_07061,,,70-15,MGG_07061,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 950,PHI:820,UniProt,P41388,EMBL,AAA34230,,,WC,beta-tubulin,,,,,,,5025,Venturia inaequalis,5025,WC,scab (apple),,,,,,,,beta-tubulin,GO:0005874,GO,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: benomyl: CHEBI:3015, CAS:17804-35-2; anti-infective: diethofencarb: CHEBI:4520, CAS:87130-20-9",,,,,sequence analysis of sensitive and resistant strains,,HJC,MU,,Not in PubMed,10.1094/Phyto-82-1348,"Koenraadt et al. (1992) Phytopathology 82, 1348-1354",,Resistant to chemical benomyl; sensitive to chemical diethofencarb,Koenraadt et al,1992,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 951,PHI:821,UniProt,Q7Z7T9,EMBL,AAP40265,,,MS9,tub2,,,,,,,38448,Monilinia fructicola,38448,MS9,brown rot (drupe),,,,,,,,beta-tubulin,GO:0005874,GO,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: benomyl: CHEBI:3015, CAS:17804-35-2; anti-infective: thiophanate-methyl: CHEBI:35014, CAS:23564-05-8",,,,,sequence analysis of sensitive and resistant strains,,,MU,14660360,PubMed,10.1128/AEM.69.12.7145-7152.2003,Ma et al. (2003) Appl Environ Microbiol. 69(12): 7145-7152,themis@uckac.edu,,Ma et al.,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 952,PHI:822,UniProt,O42772,EMBL,AAB97419,,,UK field isolate,Ip,,,,,,,1047171,Zymoseptoria tritici,54734,UK field isolate,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,succinate dehydrogenase subunit,GO:0006066; GO:0006118; GO:0000104,GO,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: carboxin: CHEBI:3405, CAS:5234-68-4",,,,,gene mutation: characterised; gene complementation,,HJC,MU,9871122,PubMed,no data found,Skinner et al. (1998) Current Genetics 34(5):393-398,,,Skinner et al.,1998,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 953,PHI:823,UniProt,P53376,EMBL,CAA56936,,,765.03.01,beta-tubulin,,,,,,,914237,Rhynchosporium commune,38038,1130,leaf blotch (barley),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,beta-tubulin,GO:0005874,GO,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: diethofencarb: CHEBI:4520, CAS:87130-20-9; anti-infective: carbendazim: CHEBI:3392, CAS:10605-21-7",,,,,biochemical analysis; gene mutation: characterised,,HJC,MU,9736529,PubMed,no data found,Hollomon et al. (1998) Antimicrob Agents Chemother. 42(9): 2171-2173,DEREK.HOLLOMON@BBSRC.AC.UK,E198G Resistant to chemical carbendazim; sensitive to chemical diethofencarb,Hollomon et al.,1998,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 954,PHI:824,UniProt,Q75WC5,EMBL,BAC98434,,,Pg-10,GyrA,,field isolate containing amino acid Ser at position 83 (wild-type),,,,,337,Burkholderia glumae,,Pg-10,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,sequence analysis of sensitive and resistant strains,,HJC,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 955,PHI:824,UniProt,Q75WC5,EMBL,BAC98434,,,Pg-10,GyrA,,pg-10R point mutation changing Ser83 to Arg83,,,,,337,Burkholderia glumae,,Pg-10,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,gene mutation: characterised,,HJC,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 956,PHI:824,UniProt,Q75WC5,EMBL,BAC98434,,,Pg-10,GyrA,,pg-10I point mutation changing Ser83 to Ile83,,,,,337,Burkholderia glumae,,Pg-10,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,gene mutation: characterised,,HJC,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 957,PHI:849,UniProt,Q75WC1,EMBL,BAC98438,,,M3,GyrA,,field isolate containing amino acid Ile at position 83,,,,,337,Burkholderia glumae,,M3,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,sequence analysis of sensitive and resistant strains,,,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 958,PHI:849,UniProt,Q75WC1,EMBL,BAC98438,,,M3,GyrA,,M3S point mutation changing Ile83 to Ser83,,,,,337,Burkholderia glumae,,M3,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,gene mutation: characterised,,,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 959,PHI:850,UniProt,Q75WC2,EMBL,BAC98437,,,FU13,GyrA,,field isolate containing amino acid Arg at position 83,,,,,337,Burkholderia glumae,,FU13,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,sequence analysis of sensitive and resistant strains,,,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 960,PHI:850,UniProt,Q75WC2,EMBL,BAC98437,,,FU13,GyrA,,FU13S point mutation changing Arg83 to Ser83,,,,,337,Burkholderia glumae,,FU13,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,gene mutation: characterised,,,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 961,PHI:851,UniProt,Q75WC3,EMBL,BAC98436,,,Pg-15,GyrA,,field isolate containing amino acid Ile at position 83,,,,,337,Burkholderia glumae,,Pg-15,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,sequence analysis of sensitive and resistant strains,,,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 962,PHI:851,UniProt,Q75WC3,EMBL,BAC98436,,,Pg-15,GyrA,,Pg-15S point mutation changing Ile83 to Ser83,,,,,337,Burkholderia glumae,,Pg-15,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,gene mutation: characterised,,,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 963,PHI:852,UniProt,Q75WC4,EMBL,BAC98435,,,Pg-7,GyrA,,field isolate containing amino acid Arg at position 83,,,,,337,Burkholderia glumae,,Pg-7,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,sequence analysis of sensitive and resistant strains,,,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 964,PHI:852,UniProt,Q75WC4,EMBL,BAC98435,,,Pg-7,GyrA,,Pg-7S point mutation changing Arg83 to Ser83,,,,,337,Burkholderia glumae,,Pg-7,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),,,,seedling,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,gene mutation: characterised,,,TKB,15345450,PubMed,10.1128/AEM.70.9.5613-5620.2004,Maeda et al. (2004) Appl Environ Microbiol. 70(9):5613-5620,yhikichi@cc.kochi-u.ac.jp,"Field isolates, isolated from rice seedlings grown from OA-treated seeds, MIC determined by growth on PY agar with serial dilutions of OA. Grouped into OA sensitive (Ser83) (wild-type), moderately resistant (Arg83) and resistant (Ile83).",Maeda et al.,2004,,,PHI-base Vers.3.3/AC updated 05_12_2016,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 965,PHI:825,UniProt,Q4JEX9,EMBL,AAQ18216,,,NFI5146,SE,,,,,,,5551,Trichophyton rubrum,5551,NFI 5146; NFI 5150,dermatophytosis,primates,9606,Homo sapiens (related: human),,,,,squalene epoxidase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: terbinafine: CHEBI:9448, CAS:91161-71-6",,,,,gene mutation: characterised,,HJC,AB,15980358,PubMed,10.1128/AAC.49.7.2840-2844.2005,Osborne et al. (2005) Antimicrob Agents Chemother. 49(7): 2840-2844,colin.osborne@pharma.novartis.com,L393F mutation resistance to terbinafine,Osborne et al.,2005,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 966,PHI:826,UniProt,Q1AMT8,EMBL,AAZ08563,,,NFI5166,SE,,,,,,,5551,Trichophyton rubrum,5551,NFI 5166,dermatophytosis,primates,9606,Homo sapiens (related: human),,,,,squalene epoxidase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: terbinafine: CHEBI:9448, CAS:91161-71-6; anti-infective: naftifine: CHEBI:7451, CAS:65472-88-0",,,,,gene mutation: characterised,,HJC,AB,16723593,PubMed,10.1128/AAC.01600-05,Osborne et al. (2006) Antimicrob Agents Chemother. 50(6): 2234-2236,colin.osborne@novartis.com,F397L mutation resistance to terbinafine and naftifine and other SE inhibitors,Osborne et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 967,PHI:828,UniProt,Q6QNB5,EMBL,AAS60234,,,,ERG1 (ERGA),,,,,,,746128,Aspergillus fumigatus,,AF293.1,aspergillosis,,,,,,,,squalene epoxidase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: terbinafine: CHEBI:9448, CAS:91161-71-6",,,,,altered gene expression / gene regulation: overexpression,,HJC,AB,15215099,PubMed,10.1128/AAC.48.7.2490-2496.2004,Liu et al. (2004) Antimicrob Agents Chemother. 48(7): 2490-2496,dkontoyi@mdanderson.org,Extra copies of gene introduced conferring terbinafine resistance,Liu et al.,2004,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 968,PHI:829,UniProt,Q6QNB5,EMBL,AAS60234,,,,ERG1 (ERGA),,,,,,,746128,Aspergillus fumigatus,,5233,aspergillosis,,,,,,,,squalene epoxidase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: terbinafine: CHEBI:9448, CAS:91161-71-6",,,,,gene mutation: characterised,,HJC,AB,16801438,PubMed,10.1128/AAC.00187-06,Rocha et al. (2006) Antimicrob Agents Chemother. 50(7): 2533-2536,perlin@phri.org,F389L mutation resistance to terbinafine,Rocha et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 969,PHI:830,UniProt,Q27PP1,EMBL,ABD48706,,,,ERGA,,,,,,,162425,Aspergillus nidulans,162425,pabaA1,aspergillosis,,,,,,,,squalene epoxidase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: terbinafine: CHEBI:9448, CAS:91161-71-6",,,,,gene mutation: characterised,,HJC,AB,16801438,PubMed,10.1128/AAC.00187-06,Rocha et al. (2006) Antimicrob Agents Chemother. 50(7): 2533-2536,perlin@phri.org,F391L mutation resistance to terbinafine,Rocha et al.,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 970,PHI:835,UniProt,Q6X9S4,EMBL,AAP81933,,,ST1/MBC,ubiquinol oxidase,,,,,,,1047171,Zymoseptoria tritici,54734,ST1/MBC,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,complex III cytochrome bc1,,,mitochondrial respiration,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: azoxystrobin: CHEBI:40909, CAS:131860-33-8",,,,,biochemical analysis; gene mutation: characterised,,HJC,KHK,15151285,PubMed,no data found,Amand et al. (2003) Commun Agric Appl Biol Sci. 68(4 Pt B): 519-531,,Cross-resistance to trifloxystrobin and kresoxim-methyl demonstrated,Amand et al,2003,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 971,PHI:836,UniProt,Q9B334,EMBL,AAK26622,,,Fel08,ubiquinol oxidase,,,,,,,34373,Blumeria graminis,62688,Fel09,powdery mildew (wheat),monocots,4564,Triticum (related: wheat),,,,,complex III cytochrome bc1,,,mitochondrial respiration,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: azoxystrobin: CHEBI:40909, CAS:131860-33-8",,,,,"sexual cross, sequencing of resistance conferring allele",,,KHK,12081463,PubMed,10.1016/S1087-1845(02)00006-3,Robinson et al. (2002) Fungal Genet Biol. 36(2): 98-106,james.brown@bbsrc.ac.uk,Cross-resistance to trifloxystrobin and kresoxim-methyl demonstrated,Robinson et al,2002,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 972,PHI:837,UniProt,Q8X215,EMBL,AAL30826,,,Daf1,os-1 / bos1 / barA,,,,,,,40559,Botrytis cinerea,40559,A1,grey mold,,,,,,,,two component histidine kinase,,,signal perception and transduction - osmosensing,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: iprodione: CHEBI:28909, CAS:36734-19-7",,,,,gene mutation: characterised,,HJC,KHK,12135574,PubMed,10.1016/S1087-1845(02)00009-9,Cui et al. (2002) Fungal Genet Biol. 36(3): 187-198,mtempleton@hortresearch.co.nz,,Cui et al,2002,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 973,PHI:838,UniProt,F9XG32,EMBL,ABO93363,,,K 1562,cyp51/erg11,,,,,,,1047171,Zymoseptoria tritici,54734,K1562,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: cyproconazole: CHEBI:81758, CAS:94361-06-5",,,,,gene mutation: characterised,,HJC,KHK,17511023,PubMed,10.1002/ps.1390,Leroux et al. (2007) Pest Manag Sci. 63(7): 688-698,lerouxp@versailles.inra.fr,TriS,Leroux et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 974,PHI:839,UniProt,F9XG32,EMBL,ABO93364,,,04-HG1,cyp51/erg11,,,,,,,1047171,Zymoseptoria tritici,54734,K1562,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: cyproconazole: CHEBI:81758, CAS:94361-06-5",,,,,gene mutation: characterised,,HJC,KHK,17511023,PubMed,10.1002/ps.1390,Leroux et al. (2007) Pest Manag Sci. 63(7): 688-698,lerouxp@versailles.inra.fr,TriR4,Leroux et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 975,PHI:840,UniProt,F9XG32,EMBL,ABO93365,,,04-DJ1,cyp51/erg11,,,,,,,1047171,Zymoseptoria tritici,54734,K1562,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: cyproconazole: CHEBI:81758, CAS:94361-06-5",,,,,gene mutation: characterised,,HJC,KHK,17511023,PubMed,10.1002/ps.1390,Leroux et al. (2007) Pest Manag Sci. 63(7): 688-698,lerouxp@versailles.inra.fr,TriR2,Leroux et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 976,PHI:841,UniProt,F9XG32,EMBL,ABO93366,,,04-JL3a,cyp51/erg11,,,,,,,1047171,Zymoseptoria tritici,54734,K1562,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: cyproconazole: CHEBI:81758, CAS:94361-06-5",,,,,gene mutation: characterised,,HJC,KHK,17511023,PubMed,10.1002/ps.1390,Leroux et al. (2007) Pest Manag Sci. 63(7): 688-698,lerouxp@versailles.inra.fr,TriR3,Leroux et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 977,PHI:842,UniProt,F9XG32,EMBL,ABO93367,,,04-JL2b,cyp51/erg11,,,,,,,1047171,Zymoseptoria tritici,54734,K1562,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: cyproconazole: CHEBI:81758, CAS:94361-06-5",,,,,gene mutation: characterised,,HJC,KHK,17511023,PubMed,10.1002/ps.1390,Leroux et al. (2007) Pest Manag Sci. 63(7): 688-698,lerouxp@versailles.inra.fr,TriR5,Leroux et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 978,PHI:843,UniProt,F9XG32,EMBL,ABO93368,,,04-WZ2,cyp51/erg11,,,,,,,1047171,Zymoseptoria tritici,54734,K1562,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: cyproconazole: CHEBI:81758, CAS:94361-06-5",,,,,gene mutation: characterised,,HJC,KHK,17511023,PubMed,10.1002/ps.1390,Leroux et al. (2007) Pest Manag Sci. 63(7): 688-698,lerouxp@versailles.inra.fr,TriR5,Leroux et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 979,PHI:844,UniProt,F9XG32,EMBL,ABO93369,,,04-AAW2,cyp51/erg11,,,,,,,1047171,Zymoseptoria tritici,54734,K1562,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: cyproconazole: CHEBI:81758, CAS:94361-06-5",,,,,gene mutation: characterised,,HJC,KHK,17511023,PubMed,10.1002/ps.1390,Leroux et al. (2007) Pest Manag Sci. 63(7): 688-698,lerouxp@versailles.inra.fr,TriR6,Leroux et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 980,PHI:845,UniProt,F9XG32,EMBL,ABO93370,,,04-XC4,cyp51/erg11,,,,,,,1047171,Zymoseptoria tritici,54734,K1562,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: cyproconazole: CHEBI:81758, CAS:94361-06-5",,,,,gene mutation: characterised,,HJC,KHK,17511023,PubMed,10.1002/ps.1390,Leroux et al. (2007) Pest Manag Sci. 63(7): 688-698,lerouxp@versailles.inra.fr,TriR6,Leroux et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 981,PHI:846,UniProt,F9XG32,EMBL,ABO93371,,,04-XC3,cyp51/erg11,,,,,,,1047171,Zymoseptoria tritici,54734,K1562,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: cyproconazole: CHEBI:81758, CAS:94361-06-5",,,,,gene mutation: characterised,,HJC,KHK,17511023,PubMed,10.1002/ps.1390,Leroux et al. (2007) Pest Manag Sci. 63(7): 688-698,lerouxp@versailles.inra.fr,TriR7,Leroux et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 982,PHI:847,UniProt,Q6F4M1,EMBL,BAD26622,,,NCIMB1947,GyrA,,,,,,,96345,Flavobacterium psychrophilum,96345,NCIMB1947,bacterial cold-water disease,bony fishes,8019,Oncorhynchus kisutch (related: coho salmon),,,,,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,sequence analysis of sensitive and resistant strains,,HJC,TKB,15240271,PubMed,10.1128/AEM.70.7.3968-3972.2004,Izumi and Aranishi (2004) Appl Environ Microbiol. 70(7): 3968-3972,sizumi@affrc.go.jp,Susceptible allele,Izumi and Aranishi,2004,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 983,PHI:848,UniProt,Q6F4K2,EMBL,BAD26642,,,FKR9801,GyrA,,,,,,,96345,Flavobacterium psychrophilum,96345,FKR9801,bacterial cold-water disease,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,,DNA gyrase (bacterial topoisomerase II),,,,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: oxolinic acid: CHEBI:138856, CAS:14698-29-4",,,,,sequence analysis of sensitive and resistant strains,,HJC,TKB,15240271,PubMed,10.1128/AEM.70.7.3968-3972.2004,Izumi and Aranishi (2004) Appl Environ Microbiol. 70(7): 3968-3972,sizumi@affrc.go.jp,Resistant allele,Izumi and Aranishi,2004,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 984,PHI:853,UniProt,Q4PCH2,EMBL,EAK83313,,,521,YAP1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,transcription factor,"GO:0009405, IMP",GO,oxidative stress response,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,AB,17616735,PubMed,10.1105/tpc.107.052332,,kahmann@mpi-marburg.mpg.de,Higher sensitivity to H2O2,Molina and Kahmann,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 985,PHI:854,UniProt,Q4PD66,EMBL,EAK82380,,,521,um01947,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,cytochrome C peroxidase precursor,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,AB,17616735,PubMed,10.1105/tpc.107.052332,,kahmann@mpi-marburg.mpg.de,Higher sensitivity to H2O2,Molina and Kahmann,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 986,PHI:855,,no data found,Broad,um10672,,,,um10672,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,haem peroxidase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,AB,17616735,PubMed,10.1105/tpc.107.052332,,kahmann@mpi-marburg.mpg.de,Higher sensitivity to H2O2,Molina and Kahmann,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 987,PHI:856,UniProt,Q5AI81,EMBL,EAL02391,,,SC5314,PDE2,,,,,,PHI:857,5476,Candida albicans,5476,DP42,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,cAMP phosphodiesterase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,AB,17614954,PubMed,10.1111/j.1365-2958.2007.05788.x,,l.stateva@manchester.ac.uk,PDE1:PDE2 double mutant is non-pathogenic,Wilson et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 988,PHI:857,UniProt,Q5AGE4,EMBL,EAL01707,,,SC5314,PDE1,,,,,,PHI:856,5476,Candida albicans,5476,DP42,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,phosphodiesterase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,AB,17614954,PubMed,10.1111/j.1365-2958.2007.05788.x,,l.stateva@manchester.ac.uk,PDE1:PDE2 double mutant is non-pathogenic,Wilson et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 989,PHI:858,UniProt,A6ZIB7,EMBL,ABS01490,,,,NOX1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,NADPH oxidase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,AB,17600089,PubMed,10.1073/pnas.0700574104,,n.j.talbot@exeter.ac.uk,,Egan et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 990,PHI:859,UniProt,A6ZIB8,EMBL,ABS01491,,,,NOX2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,NADPH oxidase,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,AB,17600089,PubMed,10.1073/pnas.0700574104,,n.j.talbot@exeter.ac.uk,,Egan et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 991,PHI:860,UniProt,Q5EMY3,EMBL,AAX07670,,,"Y34, 70-15",MSP1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,small secreted protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,AB,17590228,PubMed,10.1111/j.1574-6968.2007.00796.x,,radean2@ncsu.edu,,Jeong et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 992,PHI:860,UniProt,Q5EMY3,EMBL,AAX07670,,,"Y34, 70-15",MSP1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,small secreted protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,AB,17590228,PubMed,10.1111/j.1574-6968.2007.00796.x,,radean2@ncsu.edu,,Jeong et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 993,PHI:861,UniProt,I1S095,,FGSG_10114,,,,RAS2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),,,,,Ras GTPase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,slowed,delayed,,,,,,,,gene deletion; gene complementation,,,AB; AC,17555271,PubMed,10.1094/MPMI-20-6-0627,Bluhm et al (2007) Mol Plant Microbe Interact 20(6): 627-636,bluhm@purdue.edu,,Bluhm et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 994,PHI:861,UniProt,I1S095,,FGSG_10114,,,,RAS2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,Ras GTPase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,slowed,delayed,,,,,,,,gene deletion; gene complementation,,,AB; AC,17555271,PubMed,10.1094/MPMI-20-6-0627,Bluhm et al (2007) Mol Plant Microbe Interact 20(6): 627-636,bluhm@purdue.edu,,Bluhm et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 995,PHI:862,UniProt,Q2V086,EMBL,BAE66713,,,104-T,ClaSSD1,,,,,,,5462,Colletotrichum lagenaria,,104-T,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,,regulation of cell wall assembly,"GO:0009405, IMP; GO:0044409",GO,,loss of pathogenicity,,,yes,,,,,,,,,,,,,,gene disruption,,,AB,17542924,PubMed,10.1111/j.1365-2958.2007.05742.x,,y_kubo@kpu.ac.jp,pathogen formerly called Colletotrichum lagenarium,Tanaka et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 996,PHI:864,UniProt,A3QX02,EMBL,ABJ98717,,,AF14,ZafA,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,,regulation of zinc homeostasis,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,AB,17542914,PubMed,10.1111/j.1365-2958.2007.05726.x,,jacalera@usal.es,Germination and growth impaired in zinc-limiting media,Moreno et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 997,PHI:867,UniProt,A5H456,EMBL,ABN41482,,,IPO323,MgAtr7,chromosome 9,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,17379549,PubMed,10.1016/j.fgb.2007.02.001,,Zwiers@cbs.knaw.nl,,Zwiers et al,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 998,PHI:868,UniProt,Q70YY7,EMBL,CAD30840,,,beta,CLSTE12,,,,,,,290576,Colletotrichum lindemuthianum,290576,race beta,anthracnose,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,transcription factor,"GO:0009405, IMP",GO,,loss of pathogenicity,,,yes,,,,,,,,,,,,,,gene disruption; gene complementation,,,AB,17376073,PubMed,10.1111/j.1365-2958.2007.05639.x,,dumas@scsz.ups-tlse.fr,,Hoi et al.,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 999,PHI:871,,no data found,Broad,MGG_12656,,,70-15,MGG_12656,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1000,PHI:872,UniProt,G4N9G6,Broad,MGG_03284,,,70-15,MGG_03284,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1001,PHI:873,UniProt,G4MRV1,Broad,MGG_02443,,,70-15,MGG_02443,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1002,PHI:874,UniProt,G4NC47,Broad,MGG_00435,,,70-15,MGG_00435,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1003,PHI:875,UniProt,G4MSV0,Broad,MGG_04587,,,70-15,MGG_04587,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,loss of pathogenicity,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1004,PHI:876,,no data found,Broad,MGG_11671,,,70-15,MGG_11671,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1005,PHI:877,UniProt,G4NCL5,Broad,MGG_00383,,,70-15,MGG_00383,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1006,PHI:878,UniProt,G4NGP0,Broad,MGG_12142,,,70-15,MGG_12142,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1007,PHI:879,,no data found,Broad,MGG_13072,,,70-15,MGG_13072,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1008,PHI:880,,no data found,Broad,MGG_12365,,,70-15,MGG_12365,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1009,PHI:881,UniProt,G4MS58,Broad,MGG_04556,,,70-15,MGG_04556,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1010,PHI:882,UniProt,G4N3K2,Broad,MGG_04985,,,70-15,MGG_04985,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1011,PHI:883,UniProt,A4QYF9,Broad,MGG_08560,,,70-15,MGG_08560,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1012,PHI:884,,no data found,Broad,MGG_12556,,,70-15,MGG_12556,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1013,PHI:885,UniProt,G4MPP9,Broad,MGG_02240,,,70-15,MGG_02240,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1014,PHI:886,,no data found,Broad,MGG_13052,,,70-15,MGG_13052,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1015,PHI:887,UniProt,G4N4U0,Broad,MGG_05174,,,70-15,MGG_05174,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1016,PHI:888,UniProt,G4MUW5,Broad,MGG_01707,,,70-15,MGG_01707,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1017,PHI:889,UniProt,G4MQ91,Broad,MGG_09263,,,70-15,MGG_09263,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1018,PHI:890,UniProt,G4MPA8,Broad,MGG_07015,,,70-15,MGG_07015,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1019,PHI:891,UniProt,G4MVB6,Broad,MGG_01748,,,70-15,MGG_01748,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1020,PHI:892,,no data found,Broad,MGG_14174,,,70-15,MGG_14174,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1021,PHI:893,UniProt,G4NL37,Broad,MGG_02986,,,70-15,MGG_02986,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,hypothetical protein,,,,reduced virulence,,yes,,,,,,,,,,,,,,,gene disruption,,,KHK,17353894,PubMed,10.1038/ng2002,,yonglee@snu.ac.kr,,Jeon,2007,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1022,PHI:896,UniProt,Q4PF15,Broad,um01298,,,521,um01298,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2B of secreted proteins. Six genes predicted in cluster 2B.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1023,PHI:897,UniProt,Q4PF14,Broad,um01299,,,521,um01299,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2B of secreted proteins. Six genes predicted in cluster 2B.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1024,PHI:898,UniProt,Q4PF13,Broad,um01300,,,521,um01300,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2B of secreted proteins. Six genes predicted in cluster 2B.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1025,PHI:899,UniProt,Q4PF12,Broad,um01301,,,521,um01301,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2B of secreted proteins. Six genes predicted in cluster 2B.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1026,PHI:900,UniProt,Q4PF11,Broad,um01302,,,521,um01302,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 2B of secreted proteins. Six genes predicted in cluster 2B.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1027,PHI:901,UniProt,Q4PDC7,Broad,um01886,,,521,um01886,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,related to carboxypeptidase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 3A of secreted proteins. Three genes predicted in cluster 3A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1028,PHI:902,,no data found,Broad,um12173,,,521,um12173,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,putative protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 3A of secreted proteins. Three genes predicted in cluster 3A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1029,PHI:903,UniProt,Q4PDC5,Broad,um01888,,,521,um01888,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,probable serine-type carboxypeptidase f precursor,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 3A of secreted proteins. Three genes predicted in cluster 3A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1030,PHI:904,UniProt,Q4PCH1,Broad,um02192,,,521,um02192,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 5A of secreted proteins. Three genes predicted in cluster 5A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1031,PHI:905,UniProt,Q4PCH0,Broad,um02193,,,521,um02193,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 5A of secreted proteins. Three genes predicted in cluster 5A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1032,PHI:906,UniProt,Q4PCG9,Broad,um02194,,,521,um02194,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 5A of secreted proteins. Three genes predicted in cluster 5A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1033,PHI:907,UniProt,Q4PBP0,Broad,um02473,,,521,um02473,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,loss of pathogenicity,,,yes,,,,,,,,,,,,,,gene deletion; gene complementation,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Growth arrest early during penetration of epidemis. Gene located in cluster 5B of secreted proteins. Three genes predicted in cluster 5B.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1034,PHI:908,UniProt,Q4PBN9,Broad,um02474,,,521,um02474,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,loss of pathogenicity,,,yes,,,,,,,,,,,,,,gene deletion; gene complementation,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Growth arrest early during penetration of epidemis. Gene located in cluster 5B of secreted proteins. Three genes predicted in cluster 5B.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1035,PHI:909,UniProt,Q4PBN8,Broad,um02475,,,521,um02475,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,loss of pathogenicity,,,yes,,,,,,,,,,,,,,gene deletion; gene complementation,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Growth arrest early during penetration of epidemis. Gene located in cluster 5B of secreted proteins. Three genes predicted in cluster 5B.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1036,PHI:910,UniProt,Q4PBI0,Broad,um02533,,,521,um02533,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced. Gene located in cluster 6A of secreted proteins. Eight genes predicted in cluster 6A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1037,PHI:911,,no data found,Broad,um11451,,,521,um11451,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,related to COP9 signalosome complex subunit 6,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced. Gene located in cluster 6A of secreted proteins. Eight genes predicted in cluster 6A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1038,PHI:912,UniProt,Q4PBH8,Broad,um02535,,,521,um02535,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced. Gene located in cluster 6A of secreted proteins. Eight genes predicted in cluster 6A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1039,PHI:913,,no data found,Broad,um11416,,,521,um11416,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced. Gene located in cluster 6A of secreted proteins. Eight genes predicted in cluster 6A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1040,PHI:914,UniProt,Q4PBH6,Broad,um02537,,,521,um02537,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced. Gene located in cluster 6A of secreted proteins. Eight genes predicted in cluster 6A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1041,PHI:915,UniProt,Q4PBH5,Broad,um02538,,,521,um02538,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced. Gene located in cluster 6A of secreted proteins. Eight genes predicted in cluster 6A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1042,PHI:916,,no data found,Broad,um11417,,,521,um11417,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced. Gene located in cluster 6A of secreted proteins. Eight genes predicted in cluster 6A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1043,PHI:917,UniProt,Q4PBH3,Broad,um02540,,,521,um02540,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced. Gene located in cluster 6A of secreted proteins. Eight genes predicted in cluster 6A.,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1044,PHI:918,UniProt,Q4P9L2,Broad,um03201,,,521,um03201,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 8A of secreted proteins. Three genes predicted in cluster 8A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1045,PHI:919,UniProt,Q4P9L1,Broad,um03202,,,521,um03202,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 8A of secreted proteins. Three genes predicted in cluster 8A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1046,PHI:920,,no data found,Broad,um10403,,,521,um10403,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 8A of secreted proteins. Three genes predicted in cluster 8A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1047,PHI:921,UniProt,Q4P8E9,Broad,um03614,,,521,um03614,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 9A of secreted proteins. Three genes predicted in cluster 9A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1048,PHI:922,UniProt,Q4P8E8,Broad,um03615,,,521,um03615,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,related to glucose oxidase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 9A of secreted proteins. Three genes predicted in cluster 9A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1049,PHI:923,UniProt,Q4P8E7,Broad,um03616,,,521,um03616,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,related to DCR2-dosage-dependent cell cycle regulator,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 9A of secreted proteins. Three genes predicted in cluster 9A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1050,PHI:924,UniProt,Q4P819,Broad,um03744,,,521,um03744,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced.Gene located in cluster 10A of secreted proteins. Ten genes predicted in cluster 10A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1051,PHI:925,UniProt,Q4P818,Broad,um03745,,,521,um03745,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced.Gene located in cluster 10A of secreted proteins. Ten genes predicted in cluster 10A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1052,PHI:926,UniProt,Q4P817,Broad,um03746,,,521,um03746,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced.Gene located in cluster 10A of secreted proteins. Ten genes predicted in cluster 10A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1053,PHI:927,UniProt,Q4P816,Broad,um03747,,,521,um03747,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced.Gene located in cluster 10A of secreted proteins. Ten genes predicted in cluster 10A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1054,PHI:928,UniProt,Q4P815,Broad,um03748,,,521,um03748,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced.Gene located in cluster 10A of secreted proteins. Ten genes predicted in cluster 10A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1055,PHI:929,UniProt,Q4P814,Broad,um03749,,,521,um03749,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced.Gene located in cluster 10A of secreted proteins. Ten genes predicted in cluster 10A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1056,PHI:930,UniProt,Q4P813,Broad,um03750,,,521,um03750,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced.Gene located in cluster 10A of secreted proteins. Ten genes predicted in cluster 10A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1057,PHI:931,UniProt,Q4P812,Broad,um03751,,,521,um03751,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced.Gene located in cluster 10A of secreted proteins. Ten genes predicted in cluster 10A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1058,PHI:932,UniProt,Q4P811,Broad,um03752,,,521,um03752,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced.Gene located in cluster 10A of secreted proteins. Ten genes predicted in cluster 10A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1059,PHI:933,UniProt,Q4P810,Broad,um03753,,,521,um03753,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Incidence and size of tumours reduced.Gene located in cluster 10A of secreted proteins. Ten genes predicted in cluster 10A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1060,PHI:934,UniProt,G0X877,Broad,um05294,,,521,um05294,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1061,PHI:935,UniProt,G0X863,Broad,um05295,,,521,um05295,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1062,PHI:936,UniProt,G0X7F0,Broad,um12302,,,521,um12302,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1063,PHI:937,UniProt,G0X7P5,Broad,um10553,,,521,um10553,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1064,PHI:938,UniProt,G0X7N7,Broad,um10554,,,521,um10554,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1065,PHI:939,UniProt,G0X854,Broad,um05299,,,521,um05299,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1066,PHI:940,UniProt,G0X847,Broad,um05300,,,521,um05300,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1067,PHI:941,UniProt,G3CK64,Broad,um05301,,,521,um05301,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1068,PHI:942,UniProt,G0X840,Broad,um05302,,,521,um05302,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1069,PHI:943,UniProt,G0X828,Broad,um05303,,,521,um05303,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1070,PHI:944,UniProt,G0X7M7,Broad,um10555,,,521,um10555,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1071,PHI:945,UniProt,G0X815,Broad,um05305,,,521,um05305,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1072,PHI:946,UniProt,G0X806,Broad,um05306,,,521,um05306,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1073,PHI:947,UniProt,G0X7L8,Broad,um10556,,,521,um10556,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1074,PHI:948,UniProt,G0X801,Broad,um05308,,,521,um05308,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1075,PHI:949,UniProt,G3CK59,Broad,um05309,,,521,um05309,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1076,PHI:950,UniProt,G0X7Z5,Broad,um05310,,,521,um05310,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1077,PHI:951,UniProt,G0X7Y7,Broad,um05311,,,521,um05311,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1078,PHI:952,UniProt,G0X7X3,Broad,um05312,,,521,um05312,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1079,PHI:953,UniProt,G0X7W8,Broad,um05313,,,521,um05313,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1080,PHI:954,UniProt,G0X7V8,Broad,um05314,,,521,um05314,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1081,PHI:955,UniProt,G0X7K9,Broad,um10557,,,521,um10557,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1082,PHI:956,UniProt,G0X7U3,Broad,um05316,,,521,um05316,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,"related to transposase, pseudogene",,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1083,PHI:957,UniProt,G0X7T6,Broad,um05317,,,521,um05317,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1084,PHI:958,UniProt,G0X7S7,Broad,um05318,,,521,um05318,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1085,PHI:959,UniProt,G0X7S0,Broad,um05319,,,521,um05319,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,conserved hypothetical ustilago-specific protein,,,,reduced virulence,,,,yes,,,defective,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,"Able to grow inside host tissue, fails to induce large tumours and is defective in teleospore formation. Gene located in cluster 19A of secreted proteins.Twenty six genes predicted in cluster 19A",Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1086,PHI:960,UniProt,Q4P0Z2,Broad,um06221,,,521,um06221,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 22A of secreted proteins. Three genes predicted in cluster 22A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1087,PHI:961,UniProt,Q4P0Z1,Broad,um06222,,,521,um06222,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 22A of secreted proteins. Three genes predicted in cluster 22A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1088,PHI:962,UniProt,Q4P0Z0,Broad,um06223,,,521,um06223,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,KHK; MU,17080091,PubMed,10.1038/nature05248,,,Gene located in cluster 22A of secreted proteins. Three genes predicted in cluster 22A,Kamper,2006,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1089,PHI:963,UniProt,P11437,EMBL,AAA25725,,,,avrA,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial blight,eudicots,3847,Glycine max (related: soybean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,3027035,PubMed,no data found,,,,,1987,,,PHI-base Vers.3.3,2008-05-04,RRes,,,,,,,,,,,,,
,,Record 1090,PHI:964,UniProt,P13835,EMBL,AAA25726,,,race 4,avrB1,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial blight,eudicots,3847,Glycine max (related: soybean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,3049552,PubMed,no data found,,,,,1988,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1091,PHI:965,UniProt,P13836,EMBL,AAA88428,,,race 4,avrB2,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial blight,eudicots,3847,Glycine max (related: soybean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,3049552,PubMed,no data found,,,,,1988,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1092,PHI:966,UniProt,Q52378,EMBL,AAA83419,,,NPS3121,avrB2,,,,,,,317,Pseudomonas syringae,319,pv. phaseolicola strain NPS3121,halo blight,eudicots,3847,Glycine max (related: soybean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,7949327,PubMed,no data found,,,,,1994,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1093,PHI:967,UniProt,Q4ZX49,EMBL,AAF71496,,,B728A,avrB3,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1094,PHI:968,UniProt,Q5D157,EMBL,AAX12108,,,race 6-1448A,avrB4-1,,,,,,,317,Pseudomonas syringae,264730,pv. phaseolicola strain 1448A,halo blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,15701698,PubMed,10.1073/pnas.0409660102,,,,,2005,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1095,PHI:969,UniProt,O08242,EMBL,AAB53624,,,PT23,avrD1,,,,,,,317,Pseudomonas syringae,323,pv. tomato strain PT23,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,2132028,PubMed,no data found,,,,,1990,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1096,PHI:970,UniProt,O08242,EMBL,AAB53624,,,race 1,avrD1,,,,,,,317,Pseudomonas syringae,318,pv. glycinea race 1,bacterial blight,eudicots,3847,Glycine max (related: soybean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,9100386,PubMed,10.1094/MPMI.1997.10.3.416,,,,,1997,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1097,PHI:971,UniProt,O08243,EMBL,AAB53625,,,race 3,avrD1,,,,,,,317,Pseudomonas syringae,318,pv. glycinea race 3,bacterial blight,eudicots,3847,Glycine max (related: soybean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,9100386,PubMed,10.1094/MPMI.1997.10.3.416,,,,,1997,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1098,PHI:972,UniProt,O08243,EMBL,AAB53625,,,race 6,avrD1,,,,,,,317,Pseudomonas syringae,318,pv. glycinea race 6,bacterial blight,eudicots,3847,Glycine max (related: soybean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,9100386,PubMed,10.1094/MPMI.1997.10.3.416,,,,,1997,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1099,PHI:973,UniProt,Q52389,EMBL,AAC43431,,,PT23,avrE1,,,,,,,317,Pseudomonas syringae,323,pv. tomato strain PT23,bacterial speck,eudicots,4100,Nicotiana benthamiana (no common name found),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,16529372,PubMed,10.1094/MPMI-19-0099,,,,Badel et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1100,PHI:973,UniProt,Q52389,EMBL,AAC43431,,,PT23,avrE1,,,,,,,317,Pseudomonas syringae,323,pv. tomato strain PT23,bacterial speck,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,16529372,PubMed,10.1094/MPMI-19-0099,,,,Badel et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1101,PHI:974,UniProt,Q08242,EMBL,AAA25728,,,JL1065,avrPto1,,,,,,,317,Pseudomonas syringae,323,pv. tomato strain JL1065,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,1537802,PubMed,no data found,,,,,1993,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1102,PHI:975,UniProt,Q87Y16,EMBL,AAO57459,,,DC3000,avrPto1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,10438746,PubMed,no data found,,,,,1999,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1103,PHI:976,UniProt,Q4ZLM6,EMBL,AAY39946,,,B728A,avrPto1,,,,,,,317,Pseudomonas syringae,321,pv. syringae strain B728a,brown spot,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,16391110,PubMed,10.1128/AEM.72.1.702-712.2006,,,Study on AvrPtoB homologues from several Pseudomonas syringae pathovars elicit Pto-dependent resistance. AvrPtoB previuosly been shown to physically interact with tomato Pto kinase.,,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1104,PHI:977,UniProt,Q52537,EMBL,CAA48009,,,M2,avrRpm1 (avrPma1),,,,,,,317,Pseudomonas syringae,59511,pv. maculicola strain M2,bacterial leaf spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,1477552,PubMed,no data found,,,,,1992,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1105,PHI:978,UniProt,Q52432,EMBL,AAB51082,,,151,avrRps4,,,,,,,317,Pseudomonas syringae,59510,pv. pisi strain 151,bacterial blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,8589423,PubMed,no data found,,,,,1996,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1106,PHI:979,UniProt,Q6LAD6,EMBL,AAA71943,,,JL1065,avrRpt2,,,,,,,317,Pseudomonas syringae,323,pv. tomato strain JL1065,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,8335641,PubMed,no data found,,,,,1993,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1107,PHI:979,UniProt,Q6LAD6,EMBL,AAA71943,,,JL1065,avrRpt2,,,,,,,317,Pseudomonas syringae,323,pv. tomato strain JL1065,bacterial speck,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,8335641,PubMed,no data found,,,,,1993,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1108,PHI:979,UniProt,Q6LAD6,EMBL,AAA71943,,,JL1065,avrRpt2,,,,,,,317,Pseudomonas syringae,323,pv. tomato strain JL1065,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,8335641,PubMed,no data found,,,,,1993,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1109,PHI:980,UniProt,Q08370,,,,,61,hrmA,,,,,,,317,Pseudomonas syringae,321,pv. syringae strain 61,,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,9204563,PubMed,10.1094/MPMI.1997.10.5.580,,,,Alfano et al,1997,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1110,PHI:981,UniProt,Q8RP09,EMBL,AAL84247,,,ES4326,hopI1,,,,,,,317,Pseudomonas syringae,629265,pv. maculicola strain ES4326,bacterial leaf spot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,17350264,PubMed,10.1016/j.cub.2007.02.028,,,,Jelenska et al,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1111,PHI:981,UniProt,Q8RP09,EMBL,AAL84247,,,ES4326,hopI1,,,,,,,317,Pseudomonas syringae,629265,pv. maculicola strain ES4326,bacterial leaf spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,17350264,PubMed,10.1016/j.cub.2007.02.028,,,,Jelenska et al,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1112,PHI:982,UniProt,Q887D0,EMBL,AAO54897,,,DC3000,hopM1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,12940984,PubMed,no data found,,,,Badel et al,2003,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1113,PHI:982,UniProt,Q887D0,EMBL,AAO54897,,,DC3000,hopM1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,12940984,PubMed,no data found,,,,Badel et al,2003,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1114,PHI:983,UniProt,G3XDC5,EMBL,AAO54892,,,DC3000,hopN1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,15469508,PubMed,10.1111/j.1365-2958.2004.04285.x,,,,Lopez-Solanilla et al,2004,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1115,PHI:983,UniProt,G3XDC5,EMBL,AAO54892,,,DC3000,hopN1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4100,Nicotiana benthamiana (no common name found),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,15469508,PubMed,10.1111/j.1365-2958.2004.04285.x,,,,,2004,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1116,PHI:984,UniProt,Q888Y7,EMBL,AAL84260,,,DC3000,hopQ1-1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,other evidence,Agrobacterium mediated transient expression in tobacco,ML,ML,16529375,PubMed,10.1094/MPMI-19-0130,,,,Robert-Seilaniantz et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1117,PHI:985,UniProt,Q52394,EMBL,CAA11940,,,1302A (race 4),avrPphE,,,,,,,317,Pseudomonas syringae,319,pv. phaseolicola race 4 strain 1302A,halo blight,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,7873779,PubMed,no data found,,,,,1994,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1118,PHI:986,UniProt,Q8G8T8,EMBL,AAN52341,,,M6,avrPphEPsmM6,,,,,,,317,Pseudomonas syringae,698750,pv. maculicola strain M6,,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,12622811,PubMed,no data found,,,,,2003,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1119,PHI:987,UniProt,G3XDB9,EMBL,AAO54894,,,DC3000,hopAA1-1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,12437299,PubMed,10.1094/MPMI.2002.15.10.1014,,,,,2002,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1120,PHI:988,UniProt,Q87W48,EMBL,AAO58156,,,DC3000,hopAA1-2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,12437299,PubMed,10.1094/MPMI.2002.15.10.1014,,,,,2002,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1121,PHI:989,UniProt,Q9RBW3,EMBL,AAD47203,,,1449B (race7),HopAB1,,,,,,,317,Pseudomonas syringae,319,pv. phaseolicola race 7 strain 1449B,halo blight,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,10485919,PubMed,no data found,,,,,1999,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1122,PHI:989,UniProt,Q9RBW3,EMBL,AAD47203,,,1449B (race7),HopAB1,,,,,,,317,Pseudomonas syringae,319,pv. phaseolicola race 7 strain 1449B,halo blight,eudicots,3847,Glycine max (related: soybean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,10485919,PubMed,no data found,,,,,1999,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1123,PHI:990,UniProt,Q8RSY1,EMBL,AAL71883,,,DC3000,HopAB2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,12062102,PubMed,no data found,,,,,2002,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1124,PHI:991,UniProt,Q52431,EMBL,CAA59280,,,870A,avrPpiB1.R3,,,,,,,317,Pseudomonas syringae,59510,pv. pisi strain 870A,bacterial blight,eudicots,3888,Pisum sativum (related: pea),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,7579614,PubMed,no data found,,,,,1995,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1125,PHI:992,UniProt,Q79LY0,EMBL,AAO58160,,,DC3000,hopPtoD2 (hopAO1),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4100,Nicotiana benthamiana (no common name found),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,12828637,PubMed,no data found,,,,Bretz et al,2003,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1126,PHI:992,UniProt,Q79LY0,EMBL,AAO58160,,,DC3000,hopPtoD2 (hopAO1),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,12828637,PubMed,no data found,,,,Bretz et al,2003,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1127,PHI:992,UniProt,Q79LY0,EMBL,AAO58160,,,DC3000,hopPtoD2 (hopAO1),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,12828637,PubMed,no data found,,,,Bretz et al,2003,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1128,PHI:993,UniProt,Q52430,EMBL,AAA25727,,,race 3,avrPph3,,,,,,,317,Pseudomonas syringae,319,pv. phaseolicola race 3,halo blight,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,1666524,PubMed,no data found,,,,,1991,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1129,PHI:994,UniProt,Q6EES5,EMBL,AAQ24627,,,61,hopL,,,,,,,317,Pseudomonas syringae,321,pv. syringae strain 61,brown spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,15000392,PubMed,10.1094/MPMI.2004.17.3.254,,,,,2004,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1130,PHI:994,UniProt,Q6EES5,EMBL,AAQ24627,,,61,hopL,,,,,,,317,Pseudomonas syringae,321,pv. syringae strain 61,brown spot,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,15000392,PubMed,10.1094/MPMI.2004.17.3.254,,,,,2004,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1131,PHI:995,UniProt,Q7PC62,EMBL,DAA00391,,,B728A,hopAE1,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1132,PHI:995,UniProt,Q7PC62,EMBL,DAA00391,,,B728A,hopAE1,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1133,PHI:996,UniProt,Q4ZX47,EMBL,AAF71492,,,B728A,hopZ3,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1134,PHI:996,UniProt,Q4ZX47,EMBL,AAF71492,,,B728A,hopZ3,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1135,PHI:997,UniProt,Q4ZX85,EMBL,AAY36237,,,B728A,hopAA1,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1136,PHI:997,UniProt,Q4ZX85,EMBL,AAY36237,,,B728A,hopAA1,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1137,PHI:998,UniProt,Q4ZX82,EMBL,AAY36240,,,B728A,hopM1,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1138,PHI:998,UniProt,Q4ZX82,EMBL,AAY36240,,,B728A,hopM1,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1139,PHI:999,UniProt,Q4ZMD6,EMBL,AAY39686,,,B728A,HopAB1,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1140,PHI:999,UniProt,Q4ZMD6,EMBL,AAY39686,,,B728A,HopAB1,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,16942603,PubMed,10.1111/j.1365-2958.2006.05350.x,,,,Vinatzer et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1141,PHI:1000,UniProt,Q9K2L5,EMBL,AAF67149,,,1449A race 5 & 7,avrpphF,,,,,,,317,Pseudomonas syringae,319,pv. phaseolicola race 6 strain 1448A; pv. phaseolicola race 7 strain 1449B,halo blight,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive reaction,gene deletion; gene complementation,,ML,ML,10880434,PubMed,10.1093/emboj/19.13.3204,,,,,2000,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1142,PHI:1001,UniProt,Q7BT38,EMBL,AAC97882,,,Hi-C-13,Nec1,,,,,,,85558,Streptomyces turgidiscabies,698760,Car8,scab (potato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,secreted protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,KHK,KHK,17555268,PubMed,10.1094/MPMI-20-6-0599,,,,,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1143,PHI:1002,UniProt,I1RPI4,Broad,FG05955,,,PH-1,GCS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,glycosylceramide synthase,,,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,MU,17908205,PubMed,10.1111/j.1365-2958.2007.05955.x,,,,,,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1144,PHI:1002,UniProt,I1RPI4,Broad,FG05955,,,PH-1,GCS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),,,,,glycosylceramide synthase,,,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,MU,17908205,PubMed,10.1111/j.1365-2958.2007.05955.x,,,,,,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1145,PHI:1002,UniProt,I1RPI4,Broad,FG05955,,,PH-1,GCS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,glycosylceramide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,MU,17908205,PubMed,10.1111/j.1365-2958.2007.05955.x,,,,,,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1146,PHI:1002,UniProt,I1RPI4,Broad,FG05955,,,PH-1,GCS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,glycosylceramide synthase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,MU,17908205,PubMed,10.1111/j.1365-2958.2007.05955.x,,,,,,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1147,PHI:1003,UniProt,Q7BT38,EMBL,AAC97882,,,Hi-C-13,Nec1,,,,,,,85558,Streptomyces turgidiscabies,698760,Car8,scab (potato),eudicots,3726,Raphanus sativus (related: radish),,,,,secreted protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,KHK,KHK,17555268,PubMed,10.1094/MPMI-20-6-0599,,,,,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1148,PHI:1004,UniProt,I1RZQ2,Broad,FG09903,,,,STE7,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,MAPKK,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB; AC,17253976,PubMed,10.1111/j.1462-5822.2006.00887.x,Ramamoorthy et al. (2007) Cellular Microbiology 9(6): 1491-1506,dshah@danforthcenter.org,,Ramamoorthy et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1149,PHI:1004,UniProt,I1RZQ2,Broad,FG09903,,,,STE7,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAPKK,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB; AC,17253976,PubMed,10.1111/j.1462-5822.2006.00887.x,Ramamoorthy et al. (2007) Cellular Microbiology 9(6): 1491-1506,dshah@danforthcenter.org,,Ramamoorthy et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1150,PHI:1005,UniProt,P0C431,Broad,FG09612,,,,FgHOG1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,MAPK,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,AB; AC,17253976,PubMed,10.1111/j.1462-5822.2006.00887.x,Ramamoorthy et al. (2007) Cellular Microbiology 9(6): 1491-1506,dshah@danforthcenter.org,Did not grow in 1M NaCl,Ramamoorthy et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1151,PHI:1005,UniProt,P0C431,Broad,FG09612,,,,FgHOG1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAPK,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,AB; AC,17253976,PubMed,10.1111/j.1462-5822.2006.00887.x,Ramamoorthy et al. (2007) Cellular Microbiology 9(6): 1491-1506,dshah@danforthcenter.org,Did not grow in 1M NaCl,Ramamoorthy et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1152,PHI:1006,UniProt,I1RXX1,Broad,FG09197,,,,HMR1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,HMG-CoA reductase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,yes,,,,,,,gene deletion; gene complementation,,,AB; AC,16377218,PubMed,10.1016/j.fgb.2005.10.002,Seong et al. (2006) Fungal Genetics and Biology 43(1): 34-41,jinrong@purdue.edu,Partial gene deletion,Seong et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1153,PHI:1007,UniProt,I1RIV2,Broad,FG03747,,,,NPS6,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,non-ribosomal peptide synthetase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,AB; AC,17056706,PubMed,10.1105/tpc.106.045633,Oide et al. (2006) Plant Cell 18(10): 2836-2853,bgt1@cornell.edu,Hypersensitivity to H2O2. Increased sensitivity to iron depletion.,Oide et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1154,PHI:1008,UniProt,Q09MP5,EMBL,ABI51982,,,,NPS6,,,,,,,101162,Bipolaris oryzae,930090,WK-1C,brown spot,monocots,4530,Oryza sativa (related: rice),,,,,non-ribosomal peptide synthetase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,AB,17056706,PubMed,10.1105/tpc.106.045633,,bgt1@cornell.edu,Hypersensitivity to H2O2. Increased sensitivity to iron depletion.,Oide et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1155,PHI:1009,UniProt,Q09MP4,EMBL,ABI51983,,,,NPS6,,,,,,,29001,Alternaria brassicicola,29001,Tf383,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,non-ribosomal peptide synthetase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,AB,17056706,PubMed,10.1105/tpc.106.045633,,bgt1@cornell.edu,Hypersensitivity to H2O2. Increased sensitivity to iron depletion.,Oide et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1156,PHI:1010,UniProt,I1RN13,EMBL,XM_385547,,,,SID1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,siderophore biosynthetic gene,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,AB,20507510,PubMed,10.1111/J.1364-3703.2007.00401.X,,yangdou.wei@usask.ca,,Greenshields et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1157,PHI:1011,UniProt,I1RMG9,Broad,FG05159,,,,FET3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,ferroxidase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB,20507510,PubMed,10.1111/J.1364-3703.2007.00401.X,,yangdou.wei@usask.ca,Complementation of yeast mutant also,Greenshields et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1158,PHI:1012,UniProt,I1RNF9,Broad,FG05535,,,,GzGPA1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,G protein alpha subunit,,,,unaffected pathogenicity,,,,,,,,slightly affected,,,,,,,,,gene deletion,,,AB; AC,18227243,PubMed,10.1099/mic.0.2007/012260-0,Yu et al. (2008) Microbiology 154(Pt 2): 392-401,lee2443@snu.ac.kr,Enhanced DON and ZEA production when deleted. Female sterility.,Yu et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1159,PHI:1013,UniProt,I1RYZ7,Broad,FG09614,,,,GzGPA2,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,G protein alpha subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,slightly affected,,,,,,,,,gene deletion; gene complementation,,,AB; AC,18227243,PubMed,10.1099/mic.0.2007/012260-0,Yu et al. (2008) Microbiology 154(Pt 2): 392-401,lee2443@snu.ac.kr,,Yu et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1160,PHI:1014,UniProt,I1RZX9,Broad,FG09988,,,,GzGPA3,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,G protein alpha subunit,,,,unaffected pathogenicity,,,,,,,,slightly affected,,,,,,,,,gene deletion,,,AB; AC,18227243,PubMed,10.1099/mic.0.2007/012260-0,Yu et al. (2008) Microbiology 154(Pt 2): 392-401,lee2443@snu.ac.kr,,Yu et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1161,PHI:1015,UniProt,I1RJS2,Broad,FG04104,,,,GzGPB1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,G protein beta subunit,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,wild type (75%),,,,,,,,,gene deletion; gene complementation,,,AB; AC,18227243,PubMed,10.1099/mic.0.2007/012260-0,Yu et al. (2008) Microbiology 154(Pt 2): 392-401,lee2443@snu.ac.kr,Enhanced DON and ZEA production when deleted,Yu et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1162,PHI:1016,UniProt,A0A0E0SIZ6,EMBL,FGRAMPH1_01T18031,,,,STE11,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,MAPKKK,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB; AC,17253976,PubMed,10.1111/j.1462-5822.2006.00887.x,Ramamoorthy et al. (2007) Cellular Microbiology 9(6): 1491-1506,dshah@danforthcenter.org,,Ramamoorthy et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1163,PHI:1016,UniProt,A0A0E0SIZ6,EMBL,FGRAMPH1_01T18031,,,,STE11,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAPKKK,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB; AC,17253976,PubMed,10.1111/j.1462-5822.2006.00887.x,Ramamoorthy et al. (2007) Cellular Microbiology 9(6): 1491-1506,dshah@danforthcenter.org,,Ramamoorthy et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1164,PHI:1017,UniProt,G4NDE1,Broad,MGG_00937.5,,,B157,ABC4,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,ABC transporter,,,,reduced virulence,,yes,,,,present (no data found),,,,,,,,,,,gene disruption,,,MU,18034832,PubMed,10.1111/j.1574-6968.2007.00937.x,,,,,,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1165,PHI:1018,UniProt,Q3Y5V5,,,,,,ABC3,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,MDR transporter,,,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,MU,17189344,PubMed,10.1105/tpc.105.037861,,,,,,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1166,PHI:1018,UniProt,Q3Y5V5,,,,,,ABC3,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,MDR transporter,,,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,MU,17189344,PubMed,10.1105/tpc.105.037861,,,,,,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1167,PHI:1001,UniProt,Q7BT38,EMBL,AAC97882,,,Hi-C-13,Nec1,,,,,,,85558,Streptomyces turgidiscabies,698760,Car8,scab (potato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,secreted protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,KHK,KHK,17555268,PubMed,10.1094/MPMI-20-6-0599,,,,,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1168,PHI:1020,UniProt,A8QJI7,,,,,,XlnR,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,AB,17722701,PubMed,10.1094/MPMI-20-8-0977,,ge1hedic@uco.es,,Calero-Nieto et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1169,PHI:1021,UniProt,A6N6J8,EMBL,ABR12478,,,4287,CTF1,,,,,,,5507,Fusarium oxysporum,426428,4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,putative Zn finger transcription factor,GO:0005634; GO:0003700; GO:0008270; GO:0006355,GO,,unaffected pathogenicity,,,,,,,,wild type in liquid; reduced on plate,,,,,,,,,gene deletion; altered gene expression / gene regulation: overexpression,,,MU,18705871,PubMed,10.1111/J.1364-3703.2007.00463.X,,,Fruit and root infection,Rocha et al,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1170,PHI:1022,UniProt,A8QJI7,EMBL,ABN41464,,,4288,XLNR,,,,,,,5507,Fusarium oxysporum,5508,4288,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,putative Zn finger transcription factor,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion; altered gene expression / gene regulation: overexpression,,,MU,17722701,PubMed,10.1094/MPMI-20-8-0977,,,,,,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1171,PHI:1023,UniProt,B0BES1,EMBL,CAP12516,,,B05.10,bcnoxA,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,NADPH oxidase,GO:0009405; GO:0044412,GO,,reduced virulence,,,,yes,,,defective sclerotia formation,slightly reduced,,,,,,,,,gene deletion; gene complementation,,,AB; NB,18624644,PubMed,10.1094/MPMI-21-6-0808,,tudzyns@uni-muenster.de,"Reduced growth in presence of H2O2, defective sclerotia formation",Segmuller et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1172,PHI:1023,UniProt,B0BES1,EMBL,CAP12516,,,B05.10,bcnoxA,,,,,,PHI:1024,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,NADPH oxidase,GO:0009405; GO:0044412; GO:0044409,GO,,reduced virulence,,,yes,yes,,,defective sclerotia formation,slightly reduced,,,,,,,,,gene deletion; gene complementation,,,AB; NB,18624644,PubMed,10.1094/MPMI-21-6-0808,,tudzyns@uni-muenster.de,"Double mutant has additive effects, defective sclerotia formation",Segmuller et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1173,PHI:1024,UniProt,B0BES2,EMBL,CAP12517,,,B05.10,bcnoxB,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,NADPH oxidase,GO:0009405; GO:0044409,GO,,reduced virulence,,,yes,,,,defective sclerotia formation,slightly reduced,,,,,,,,,gene deletion; gene complementation,,,AB; NB,18624644,PubMed,10.1094/MPMI-21-6-0808,,tudzyns@uni-muenster.de,"Reduced growth in presence of H2O2, defective sclerotia formation",Segmuller et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1174,PHI:1024,UniProt,B0BES2,EMBL,CAP12517,,,B05.10,bcnoxB,,,,,,PHI:1023,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,NADPH oxidase,GO:0009405; GO:0044412; GO:0044409,GO,,reduced virulence,,,yes,yes,,,defective sclerotia formation,slightly reduced,,,,,,,,,gene deletion; gene complementation,,,AB; NB,18624644,PubMed,10.1094/MPMI-21-6-0808,,tudzyns@uni-muenster.de,"Double mutant has additive effects, defective sclerotia formation",Segmuller et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1175,PHI:1025,UniProt,B0BER8,EMBL,CAP12326,,,B05.10,bcnoxR,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,regulatory subunit of Nox complex,GO:0009405; GO:0044412; GO:0044409,GO,,reduced virulence,,,yes,yes,,,defective sclerotia formation,slightly reduced,,,,,,,,,gene deletion,,,AB; NB,18624644,PubMed,10.1094/MPMI-21-6-0808,,tudzyns@uni-muenster.de,"Reduced growth in presence of H2O2, defective sclerotia formation",Segmuller et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1176,PHI:1026,UniProt,P78585,EMBL,AAB39564,,,B05.10,bcplc1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,phospholipase C,,,,reduced virulence,,,no,yes,,reduced,,reduced,reduced,yes,,,,,,,gene deletion,,,NB,18208491,PubMed,10.1111/j.1365-2958.2008.06105.x,,tudzyns@uni-muenster.de,,Schumacher et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1177,PHI:1027,UniProt,O94100,EMBL,AAC64374,,,B05.10,bcpg1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,endopolygalacturonase,,,,reduced virulence,,,no,yes,,,,,,,,,,,,,gene disruption,,,NB,9768518,PubMed,10.1094/MPMI.1998.11.10.1009,,jan.vankan@medew.fyto.wau.nl,"Reduced growth on polygalacturonic acid as sole carbon source, Wild type growth on sucrose",ten Have et al.,1998,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1178,PHI:1027,UniProt,O94100,EMBL,AAC64374,,,B05.10,bcpg1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,23211,Pyrus communis (related: pear),,,,,endopolygalacturonase,,,,reduced virulence,,,no,yes,,,,,,,,,,,,,gene disruption,,,NB,,Not in PubMed,10.1094/PDIS-91-10-1337,"Akagi and Stotz (2007) Plant Disease 91, 1337-1344",stotzhe@hort.oregonstate.edu,,Akagi and Stotz,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1179,PHI:1027,UniProt,O94100,EMBL,AAC64374,,,B05.10,bcpg1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,,endopolygalacturonase,,,,reduced virulence,,,no,yes,,,,,,,,,,,,,gene disruption,,,NB,9768518,PubMed,10.1094/MPMI.1998.11.10.1009,,jan.vankan@medew.fyto.wau.nl,Reduced radial growth when grown on polygalacturonic acid as sole carbon source,ten Have et al.,1998,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1180,PHI:1027,UniProt,O94100,EMBL,AAC64374,,,B05.10,bcpg1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,endopolygalacturonase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,NB,9768518,PubMed,10.111/J.1364-3703.2005.00312.X,,jan.vankan@wur.nl,,Kars et al.,2005,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1181,PHI:1027,UniProt,O94100,EMBL,AAC64374,,,B05.10,bcpg1,,,,,,PHI:1028,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,endopolygalacturonase,,,,reduced virulence,,,no,yes,,,,,,,,,,,,,gene disruption,,,NB,9768518,PubMed,10.111/J.1364-3703.2005.00312.X,,jan.vankan@wur.nl,,Kars et al.,2005,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1182,PHI:1027,UniProt,O94100,EMBL,AAC64374,,,B05.10,bcpg1,,,,,,PHI:1028,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,endopolygalacturonase,,,,reduced virulence,,,no,yes,,,,,,,,,,,,,gene disruption,,,NB,9768518,PubMed,10.111/J.1364-3703.2005.00312.X,,jan.vankan@wur.nl,,Kars et al.,2005,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1183,PHI:1028,UniProt,Q9C2Y1,EMBL,CAC29255,,,Bd90,bcpme1,,,,,,,40559,Botrytis cinerea,40559,Bd90,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,pectin methylesterase,,,,reduced virulence,,,yes,yes,,,,,,,,,,,,,gene disruption; gene complementation,,,NB,12744465,PubMed,10.1094/MPMI.2003.16.4.360,,boccara@jussieu.fr,,Valette-Collet et al.,2003,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1184,PHI:1028,UniProt,Q9C2Y1,EMBL,CAC29255,,,Bd90,bcpme1,,,,,,,40559,Botrytis cinerea,40559,Bd90,grey mold,eudicots,3750,Malus domestica (related: apple),,,,,pectin methylesterase,,,,reduced virulence,,,no,yes,,,,,,,,,,,,,gene disruption; gene complementation,,,NB,12744465,PubMed,10.1094/MPMI.2003.16.4.360,,boccara@jussieu.fr,,Valette-Collet et al.,2003,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1185,PHI:1028,UniProt,Q9C2Y1,EMBL,CAC29255,,,Bd90,bcpme1,,,,,,,40559,Botrytis cinerea,40559,Bd90,grey mold,eudicots,3603,Vitis (no common name found),,,,,pectin methylesterase,,,,reduced virulence,,,no,yes,,,,,,,,,,,,,gene disruption; gene complementation,,,NB,12744465,PubMed,10.1094/MPMI.2003.16.4.360,,boccara@jussieu.fr,,Valette-Collet et al.,2003,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1186,PHI:1028,UniProt,Q9C2Y1,EMBL,CAC29255,,,B05.10,bcpme1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,pectin methylesterase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,NB,9768518,PubMed,10.111/J.1364-3703.2005.00312.X,,jan.vankan@wur.nl,No pectin methylesterase activity,Kars et al.,2005,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1187,PHI:1028,UniProt,Q9C2Y1,EMBL,CAC29255,,,B05.10,bcpme1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,pectin methylesterase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,NB,9768518,PubMed,10.111/J.1364-3703.2005.00312.X,,jan.vankan@wur.nl,No pectin methylesterase activity,Kars et al.,2005,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1188,PHI:1028,UniProt,Q9C2Y1,EMBL,CAC29255,,,B05.10,bcpme1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,23211,Pyrus communis (related: pear),,,,,pectin methylesterase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,NB,,Not in PubMed,10.1094/PDIS-91-10-1337,,stotzhe@hort.oregonstate.edu,,Akagi and Stotz,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1189,PHI:1028,UniProt,Q9C2Y1,EMBL,CAC29255,,,B05.10,bcpme1,,,,,,PHI:1027,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,pectin methylesterase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,NB,,Not in PubMed,10.111/J.1364-3703.2005.00312.X,,jan.vankan@wur.nl,,Kars et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1190,PHI:1028,UniProt,Q9C2Y1,EMBL,CAC29255,,,B05.10,bcpme1,,,,,,PHI:1027,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,pectin methylesterase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,NB,,Not in PubMed,10.111/J.1364-3703.2005.00312.X,,jan.vankan@wur.nl,,Kars et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1191,PHI:1028,UniProt,Q9C2Y1,EMBL,CAC29255,,,B05.10,bcpme1,,,,,,PHI:1027,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,23211,Pyrus communis (related: pear),,,,,pectin methylesterase,,,,reduced virulence,,,no,yes,,,,,,,,,,,,,gene disruption,,,NB,,Not in PubMed,10.1094/PDIS-91-10-1337,,stotzhe@hort.oregonstate.edu,,Akagi and Stotz,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1192,PHI:1029,UniProt,Q8X116,EMBL,CAD21438,,,B05.10,bcpme2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,pectin methylesterase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,NB,,Not in PubMed,10.111/J.1364-3703.2005.00312.X,"Kars et al (2005) Mol. Plant Pathol. 6, 641-652",jan.vankan@wur.nl,,Kars et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1193,PHI:1029,UniProt,Q8X116,EMBL,CAD21438,,,B05.10,bcpme2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,pectin methylesterase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,NB,,Not in PubMed,10.111/J.1364-3703.2005.00312.X,"Kars et al (2005) Mol. Plant Pathol. 6, 641-652",jan.vankan@wur.nl,,Kars et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1194,PHI:1029,UniProt,Q8X116,EMBL,CAD21438,,,B05.10,bcpme2,,,,,,PHI:1028,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,pectin methylesterase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,NB,,Not in PubMed,10.111/J.1364-3703.2005.00312.X,"Kars et al (2005) Mol. Plant Pathol. 6, 641-652",jan.vankan@wur.nl,,Kars et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1195,PHI:1029,UniProt,Q8X116,EMBL,CAD21438,,,B05.10,bcpme2,,,,,,PHI:1028,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,pectin methylesterase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,NB,,Not in PubMed,10.111/J.1364-3703.2005.00312.X,"Kars et al (2005) Mol. Plant Pathol. 6, 641-652",jan.vankan@wur.nl,,Kars et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1196,PHI:1030,UniProt,O60034,EMBL,CAA93142,,,B05.10,bcatrA,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,NB,18515055,PubMed,10.1016/j.mycres.2008.01.005,,miruocco@unina.it,,Del Sorbo et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1197,PHI:1030,UniProt,O60034,EMBL,CAA93142,,,B05.10,bcatrA,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,NB,18515055,PubMed,10.1016/j.mycres.2008.01.005,,miruocco@unina.it,"Accumulation of transcripts 6, 12 and 24 hours post inoculation",Del Sorbo et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1198,PHI:1030,UniProt,O60034,EMBL,CAA93142,,,B05.10,bcatrA,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3906,Vicia faba (related: fava bean),,,,,ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,NB,18515055,PubMed,10.1016/j.mycres.2008.01.005,,miruocco@unina.it,,Del Sorbo et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1199,PHI:1031,UniProt,A1IVT7,EMBL,CAJ85638,,,B05.10,bcSAK1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,,stress activated MAPK,,,,reduced virulence,,yes,yes,yes,,absent,,reduced,,,,,,,,,gene deletion; gene complementation,,,NB,17189492,PubMed,10.1128/EC.00153-06,,tudzyns@uni-muenster.de,"Increased osmotic and H2O2 sensitivity, increased sclerotia",Segmuller et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1200,PHI:1032,UniProt,Q000T6,EMBL,ABJ51957,,,B05.10,Bmp3,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,monocots,4679,Allium cepa (related: onion),,,,,MAPK,,,,reduced virulence,,yes,yes,yes,,aberrant,,reduced,aberrant (overelongated germ tube),,,,,,,,gene disruption; gene complementation,,,NB,20507489,PubMed,10.1111/J.1364-3703.2007.00383.X,"Rui and Hahn 2007) Mol. Plant Pathol. 8, 173-184",hahn@rhrk.uni-kl.de,"Increased sensitivity to low osmolarity, loss of sclerotia",Rui and Hahn,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1201,PHI:1032,UniProt,Q000T6,EMBL,ABJ51957,,,B05.10,Bmp3,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,MAPK,,,,reduced virulence,,yes,yes,yes,,aberrant,,reduced,aberrant (overelongated germ tube),,,,,,,,gene disruption; gene complementation,,,NB,20507489,PubMed,10.1111/J.1364-3703.2007.00383.X,"Rui and Hahn 2007) Mol. Plant Pathol. 8, 173-184",hahn@rhrk.uni-kl.de,"Increased sensitivity to low osmolarity, loss of sclerotia",Rui and Hahn,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1202,PHI:1032,UniProt,Q000T6,EMBL,ABJ51957,,,B05.10,Bmp3,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,13546,Gerbera (no common name found),,,,petal,MAPK,,,,reduced virulence,,yes,yes,yes,,aberrant,,reduced,aberrant (overelongated germ tube),,,,,,,,gene disruption; gene complementation,,,NB,20507489,PubMed,10.1111/J.1364-3703.2007.00383.X,"Rui and Hahn 2007) Mol. Plant Pathol. 8, 173-184",hahn@rhrk.uni-kl.de,"Increased sensitivity to low osmolarity, loss of sclerotia",Rui and Hahn,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1203,PHI:1034,UniProt,O60038,EMBL,CAA04716,,,T5,Cpcat1,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,secreted catalase,,,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,NB; AC,9675893,PubMed,10.1094/MPMI.1998.11.8.772,Garre et al. (1998) Molecular Plant Microbe Interactions 11(8): 772-783,tudzyns@uni-muenster.de,85 fold reduction in catalase activity,Garre et al.,1998,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1204,PHI:1035,UniProt,B0BER9,EMBL,CAP12327,,,T5,Cpnox1,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,NADPH oxidase,,,,reduced virulence,,yes,,yes,,,,wild type,reduced,,,,,,,,gene disruption; gene complementation,,,NB; AC,18705873,PubMed,10.1111/j.1364-3703.2008.00466.x,Giesbert et al. (2008) Molecular Plant Pathology 9(3): 317-327,tudzyns@uni-muenster.de,"Sclerotia were few, misshapen and not fully matured. Expression highest at late stage of infection",Giesbert et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1205,PHI:1036,UniProt,B0B5Z8,EMBL,CAO82105,,,T5,Rac,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,GTPase,,,,loss of pathogenicity,,yes,yes,yes,,absent (none),,aberrant (hyperbranching),,,,,,,,,gene deletion; gene complementation,,,NB; AC,18284596,PubMed,10.1111/j.1365-2958.2008.06159.x,Rolke and Tudzynski (2008) Molecular Microbiology 68(2): 405-423,tudzyns@uni-muenster.de,Rac and Cla4 interact directly,Rolke and Tudzynski,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1206,PHI:1037,UniProt,B0B5Z9,EMBL,CAO82106,,,T5,Cla4,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,p21-activated kinase,,,,loss of pathogenicity,,yes,yes,yes,,absent (none),,aberrant (hyperbranching),,,,,,,,,gene deletion; gene complementation,,,NB; AC,18284596,PubMed,10.1111/j.1365-2958.2008.06159.x,Rolke and Tudzynski (2008) Molecular Microbiology 68(2): 405-423,tudzyns@uni-muenster.de,Rac and Cla4 interact directly,Rolke and Tudzynski,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1207,PHI:1038,UniProt,A3KLI8,EMBL,CAM56211,,,T5,Ku70,,,,,,,5111,Claviceps purpurea,5111,20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,,subunit of a three protein DNA-dependent protein kinase complex,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,,,,,,,,gene deletion,,,NB; AC,17560817,PubMed,10.1016/j.fgb.2007.04.008,Haarmann et al. (2007) Fungal Genetics and Biology 45(1): 35-44,tudzyns@uni-muenster.de,,Haarmann et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1208,PHI:1039,UniProt,A3KLI8,EMBL,CAM56211,,,T5,Ku70,,,,,,,5111,Claviceps purpurea,5111,PI,ergot,monocots,4550,Secale cereale (related: rye),,,,,subunit of a three protein DNA-dependent protein kinase complex,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,,,,,,,,gene deletion,,,NB; AC,17560817,PubMed,10.1016/j.fgb.2007.04.008,Haarmann et al. (2007) Fungal Genetics and Biology 45(1): 35-44,tudzyns@uni-muenster.de,Non pathogenic strain,Haarmann et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1209,PHI:1040,UniProt,B5DBZ7,EMBL,AM905386,,,v23.1.3,Lmgpi15,,,,,,,5022,Leptosphaeria maculans,,v23.1.3,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,component of GPI anchor biosynthetic pathway,,,glycosylphosphatidylinositol anchor biosynthesis,reduced virulence,,,,yes,,,,reduced by up to 40%,,,,,,,,,gene disruption; gene complementation,,BH,SD; AC,18557818,PubMed,10.1111/j.1469-8137.2008.02522.x,Remy et al. (2008) New Phytologist 179:1105-1120,rouxel@versailles.inra.fr,Tested in B. napus cv. Westar,Remy et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1210,PHI:1041,UniProt,B3LDT4,EMBL,AM933613,,,v23.1.3,Lmpma1,,,,,,,5022,Leptosphaeria maculans,,v23.1.3,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,plasma membrane H+ATPase,,,,loss of pathogenicity,,yes,,,,,,wild type,blocked on plant host surface,,,,,,,,gene disruption; gene complementation,,BH,SD; AC,18538267,PubMed,10.1016/j.fgb.2008.04.008,Remy et al. (2008) Fungal Genetics and Biology 45:1122-1134,rouxel@versailles.inra.fr,Tested in B. napus cv. Westar,Remy et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1211,PHI:1042,UniProt,Q1G7H6,,,,,IPO323,MgSlt2,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,MAP kinase,,,signal transduction,reduced virulence,,,,yes,,defective,,slowed,wild type,,,,,,,,gene disruption,,,SD,16610742,PubMed,10.1094/MPMI-19-0389,,gert.kema@wur.nl,,Mehrabi et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1212,PHI:1043,UniProt,Q1KTF2,Ensembl Genomes,Mycgr3G76502,,,IPO323,MgHog1,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,MAP kinase,,,,loss of pathogenicity,,yes,,,,,,aberrant (altered hyphal morphology),,,,,,,,,gene disruption,,,SD,17073308,PubMed,10.1094/MPMI-19-1262,,gert.kema@wur.nl,,Mehrabi et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1213,PHI:1044,UniProt,F9X6J7,Ensembl Genomes,Mycgr3G99725,,,IPO323,MgTpk2,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,protein kinase A subunit c,,,,reduced virulence,,no,no,no,,defective,,slightly reduced until 48h,wild type,,,,,,,,gene disruption,,,SD,,Not in PubMed,10.1111/J.1364-3703.2006.00361x,Mehrabi et al. (2006) MOLECULAR PLANT PATHOLOGY 7 (6) 565 - 577,gert.kema@wur.nl,,Mehrabi et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1214,PHI:1045,UniProt,F9WW98,EMBL,EGP92546,,,IPO323,MgBcy1,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,protein kinase A subunit r,,,,reduced virulence,,no,no,no,,defective,,slightly reduced until 48h,wild type,,,,,,,,gene disruption,,,SD,,Not in PubMed,10.1111/J.1364-3703.2006.00361x,Mehrabi et al. (2006) MOLECULAR PLANT PATHOLOGY 7 (6) 565 - 577,gert.kema@wur.nl,,Mehrabi et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1215,PHI:1046,UniProt,A0ST43,EMBL,ABK64182,,,,CTB5,,,,,,,29003,Cercospora nicotianae,29003,14,frog-eye leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,oxidoreductase,,,cercosporin biosynthesis,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,SD,17660442,PubMed,10.1099/mic.0.2007/007294-0,,krchung@ufl.edu,"Pathogenicity tested on detached leaves, blocked in cercosporin biosynthesis",Chen et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1216,PHI:1047,UniProt,A0ST44,EMBL,ABK64183,,,,CTB6,,,,,,,29003,Cercospora nicotianae,29003,14,frog-eye leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,oxidoreductase,,,cercosporin biosynthesis,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,SD,17660442,PubMed,10.1099/mic.0.2007/007294-0,,krchung@ufl.edu,"Pathogenicity tested on detached leaves, blocked in cercosporin biosynthesis",Chen et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1217,PHI:1048,UniProt,A0ST45,EMBL,ABK64184,,,,CTB7,,,,,,,29003,Cercospora nicotianae,29003,14,frog-eye leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,oxidoreductase,,,cercosporin biosynthesis,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,SD,17660442,PubMed,10.1099/mic.0.2007/007294-0,,krchung@ufl.edu,"Pathogenicity tested on detached leaves, blocked in cercosporin biosynthesis",Chen et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1218,PHI:1049,UniProt,A0ST41,EMBL,ABK64180,,,,CTB2,,,,,,,29003,Cercospora nicotianae,29003,14,frog-eye leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,methyltransferase,,,cercosporin biosynthesis,reduced virulence,,,,,,,,slightly faster,,,,,,,,,gene deletion; gene complementation,,,SD,17462021,PubMed,10.1111/j.1365-2958.2007.05689.x,,krchung@ufl.edu,"Pathogenicity tested on detached leaves, blocked in cercosporin biosynthesis",Chen et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1219,PHI:1050,UniProt,A0ST46,EMBL,ABK64185,,,,CTB8,,,,,,,29003,Cercospora nicotianae,29003,14,frog-eye leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,transcriptional activator,,,cercosporin biosynthesis,reduced virulence,,,,,,,,slightly faster,,,,,,,,,gene deletion; gene complementation,,,SD,17462021,PubMed,10.1111/j.1365-2958.2007.05689.x,,krchung@ufl.edu,"Pathogenicity tested on detached leaves, blocked in cercosporin biosynthesis",Chen et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1220,PHI:1051,UniProt,Q2I0M6,EMBL,ABC79591,,,,CTB3,,,,,,,29003,Cercospora nicotianae,29003,14,frog-eye leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,dual methyltransferase and FAD-dependent monooxygenase,,,cercosporin biosynthesis,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; gene complementation,,,SD,17074519,PubMed,10.1016/j.fgb.2006.08.005,,krchung@ufl.edu,"Pathogenicity tested on detached leaves, blocked in cercosporin biosynthesis",Dekkers et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1221,PHI:1052,UniProt,B2CG58,EMBL,ACB38886,,,,PHL1,,,,,,,135779,Cercospora zeae-maydis,135779,SCOH1-5,grey leaf spot (maize),monocots,4577,Zea mays (related: maize),,,,,cryptochrome/6-4 photolyase,,,DNA repair,unaffected pathogenicity,,no,no,no,,increased (five times more conidia than WT produced in constant darkness),,,,,,,,,,,gene disruption,,,SD,18682297,PubMed,10.1016/j.fgb.2008.07.005,,larry.dunkle@ars.usda.gov,"Reduced cercosporin biosynthesis, reduced recovery after UV irradiation",Bluhm and Dunkle,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1222,PHI:1053,UniProt,Q66WP9,EMBL,AY7000094,,,,AbNIK1,,,,,,,29001,Alternaria brassicicola,29001,,black spot,eudicots,3726,Raphanus sativus (related: radish),,,,,group III histidine kinase,,,osmosensitivity pathway; sensitivity to dicarboximide fungicides,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,,,,,,,radical length reduced by all isolates,sequence analysis of sensitive and resistant strains,,,SD,,Not in PubMed,10.1111/j.1365-3059.2008.01864.x,"Iacomi-Vasilescu et al. (2008) Plant Pathology, 57, 937 - 947",simoneau@univ-angers.fr,"dicarboximide resistant isolate unaffected pathogenicity in single inoculation, but less aggressive in mixed inoculation with wildtype Field and laboratory isolates characterised for sensitivity to dicarboximide fungicides in Avenot et al. 2005, Current Genetics,47, 234 - 243",Iacomi-Vasilescu et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1223,PHI:1054,UniProt,Q8TFN6,EMBL,AAL23717,,,,CgCHSI,,,,,,,31870,Colletotrichum graminicola,,M2,leaf anthracnose (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),,,,,chitin synthase class I,,,chitin biosynthesis,unaffected pathogenicity,,,,,,wild type,,,,,,,,,,,gene disruption,,,SD,17990963,PubMed,10.1094/MPMI-20-12-1555,,holger.deising@landw.uni-halle.de,,Werner et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1224,PHI:1055,UniProt,Q8TFN5,EMBL,AAL23718,,,,CgCHSIII,,,,,,,31870,Colletotrichum graminicola,,M2,leaf anthracnose (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),,,,,chitin synthase class III,,,chitin biosynthesis,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene disruption,,,SD,17990963,PubMed,10.1094/MPMI-20-12-1555,,holger.deising@landw.uni-halle.de,,Werner et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1225,PHI:1056,UniProt,Q8TFN4,EMBL,AAL23719,,,,CgCHSV,,,,,,,31870,Colletotrichum graminicola,,M2,leaf anthracnose (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),,,,,chitin synthase class V,,,chitin biosynthesis,reduced virulence,,yes,yes,yes,,aberrant (altered morphology),,aberrant (altered morphology),,,,,,,,,gene disruption,,,SD,17990963,PubMed,10.1094/MPMI-20-12-1555,,holger.deising@landw.uni-halle.de,,Werner et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1226,PHI:1057,UniProt,A5HF03,EMBL,ABP98949,,,Guy11,MTP1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,type II integral membrane protein,,,,unaffected pathogenicity,,yes,,,,reduced,,,delayed,,,,,,,,gene deletion; gene complementation,,,ND,18600780,PubMed,10.1631/jzus.B0820015,,jplu@zju.edu.cn; fuchenglin@zju.edu.cn,,Lu et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1227,PHI:1057,UniProt,A5HF03,EMBL,ABP98949,,,Guy11,MTP1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,type II integral membrane protein,,,,unaffected pathogenicity,,yes,,,,reduced,,,delayed,,,,,,,,gene deletion; gene complementation,,,ND,18600780,PubMed,10.1631/jzus.B0820015,,jplu@zju.edu.cn; fuchenglin@zju.edu.cn,,Lu et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1228,PHI:1058,UniProt,Q1HGK2,EMBL,ABF48563,,,70-15,MoSNF1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,MoSNF1 protein,,,,reduced virulence,,yes,,,,reduced; aberrant,,,aberrant,,,,,,,,gene deletion; gene complementation,,,ND,18595748,PubMed,10.1016/j.fgb.2008.05.003,,,reduced growth on various carbon sources independent of glucose,Yi et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1229,PHI:1061,UniProt,A0SXQ6,EMBL,ABK60346,,,70-15,MgRho3,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,encode a homolog of Rho GTPases,,,,loss of pathogenicity,,yes,,,,aberrant (more slender),,,delayed,,,,,,,,gene deletion,,,ND,17933908,PubMed,10.1128/EC.00104-07,,zonghuaw@163.com ; lgd@fjau.edu.cn,,Zheng et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1230,PHI:1063,UniProt,Q2Q466,EMBL,ABB30152,,,Guy11,MNH6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,nonhistone protein containing an HMG1 box,,,,reduced virulence,,yes,yes,,,aberrant (more slender),,,,,,,,,,,gene deletion; gene complementation,,,ND,17644013,PubMed,10.1016/j.fgb.2007.06.003,,,,Lu et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1231,PHI:1063,UniProt,Q2Q466,EMBL,ABB30152,,,Guy11,MNH6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,nonhistone protein containing an HMG1 box,,,,reduced virulence,,yes,yes,,,aberrant (more slender),,,,,,,,,,,gene deletion; gene complementation,,,ND,17644013,PubMed,10.1016/j.fgb.2007.06.003,,,,Lu et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1232,PHI:1064,UniProt,Q875L7,EMBL,AAN46744,,,Guy11,TPS1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,controls expressionn of nitrogen metabolite repressor gene NMR1,,,,loss of pathogenicity,,yes,,,,aberrant,,,aberrant,,,,,,,,gene deletion,,,ND,17641690,PubMed,10.1038/sj.emboj.7601795,,N.J.Talbot@exeter.ac.uk,mutants is not able to grow on glucose as a sole carbon source is due to a role for Tps1 in the control of NADPH levels.,Wilson et al.,2007,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1233,PHI:1070,UniProt,A9YDN6,EMBL,ABX79379,,,,MIG1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,encodes a MADS-box transcription factor,,,,loss of pathogenicity,,,,yes,,,,,,,,,,,,,gene deletion,,,ND,18344407,PubMed,10.1128/EC.00009-08,,jinrong@purdue.edu,MIG1 may function downstream from MPS1 to regulate genes required for overcoming plant defense responses,Mehrabi et al,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1234,PHI:1071,UniProt,Q705V7,EMBL,CAF05793,,,,Gas1,,,,,,,5270,Ustilago maydis,,CL13,smut (corn),monocots,4577,Zea mays (related: maize),,,,,encoding an endoplasmic reticulum glucosidase 2,,,,loss of pathogenicity,,,,yes,,,,,,,,,,,,,gene deletion,,,ND,16272431,PubMed,10.1105/tpc.105.036285,,kahmann@staff.uni-marburg.de,,Schirawski et al,2005,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1235,PHI:1072,UniProt,C5MK57,EMBL,ACR82519,,,IPO323,STE7,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,MAP kinase kinase,,,signal transduction,loss of pathogenicity,,"yes (only yeast-like growth, no filament formation)",yes (does not go through stomata),,,defective,,aberrant (altered hyphal morphology),,,,,,,,,gene deletion; gene complementation,,,MU; RM,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,,Kramer et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1236,PHI:1073,UniProt,C6KEF4,EMBL,ACS91346,,,IPO323,STE11,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,MAP kinase kinase kinase,,,signal transduction,loss of pathogenicity,,"yes (only yeast-like growth, no filament formation)",yes (does not go through stomata),,,defective,,aberrant (altered hyphal morphology),,,,,,,,,gene deletion; gene complementation,,,MU; RM,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,,Kramer et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1237,PHI:1074,UniProt,C6K2F1,EMBL,ACS34772,,,IPO323,STE50,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,MAP kinase scaffolding protein,,,signal transduction,reduced virulence,,yes (reduced; aberrant),yes (reduced),yes (reduced),,defective,,aberrant (altered hyphal morphology),,,,,,,,,gene deletion; gene complementation,,,MU; RM,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,,Kramer et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1238,PHI:1075,UniProt,C5J0G7,EMBL,ACS29558,,,IPO323,STE12,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,signal transduction,reduced virulence,,no,no,no (delayed by 5 days),,wild type,,wild type,,,,,,,,,gene deletion; gene complementation,,,MU; RM,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,delayed pathogenicity; fully pathogenic at the end,Kramer et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1239,PHI:1076,UniProt,C6KEF5,EMBL,ACS91347,,,IPO323,STE20,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,,,,signal transduction,unaffected pathogenicity,,no,no,no,,wild type,,wild type,,,,,,,,,gene deletion; gene complementation,,,MU; RM,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,"budds on minimal medium, while wild type growth filamentous",Kramer et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1240,PHI:1078,UniProt,A0A0E0SBS3,EMBL,FGRAMPH1_01T22903,,,,Mes1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,homologue of Aspergillus nidulans MesA,"GO:0009405, IMP",GO,,reduced virulence,,,,,,reduced; aberrant (altered morphology),reduced,slightly reduced,aberrant,,,,,,,,gene deletion; gene complementation,,,AB; AC,18339563,PubMed,10.1016/j.fgb.2008.01.007,Rittenour and Harris (2008) Fungal Genetics and Biology 45(6): 933-946,sharri1@unlnotes.unl.edu,Conidia shorter and wider than wild type,Rittenour and Harris,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1241,PHI:1079,UniProt,I1RWL9,Broad,FGSG_08695,,,,Pls1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,tetraspanin,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB; AC,18339563,PubMed,10.1016/j.fgb.2008.01.007,Rittenour and Harris (2008) Fungal Genetics and Biology 45(6): 933-946,sharri1@unlnotes.unl.edu,,Rittenour and Harris,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1242,PHI:1080,UniProt,I1RCP1,Broad,FG01364,,,,Cch1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,putative voltage-gated calcium ion channel,,,,unaffected pathogenicity,,,,,,,no forcible discharge,slowed,,,,,,,,,gene deletion; gene complementation,,,AB,18083828,PubMed,10.1128/EC.00248-07,,trail@msu.edu,Sexual development slowed,Hallen and Trail,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1243,PHI:1080,UniProt,I1RCP1,Broad,FG01364,,,,Cch1,,,,,,PHI:2350,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,putative voltage-gated calcium ion channel,,,,unaffected pathogenicity,,,,,,,no forcible discharge,slowed,,,,,,,,,gene deletion; gene complementation,,,AB,18083828,PubMed,10.1128/EC.00248-07,,trail@msu.edu,Sexual development slowed,Hallen and Trail,2008,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1244,PHI:1081,UniProt,Q0TVA4,Broad,SNOG_16571,,,,ToxA,,,,,,,13684,Parastagonospora nodorum,321614,SN15; Sn2000,glume blotch,monocots,4564,Triticum (related: wheat),,,,,toxin,"GO:0009405, IMP",GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,RO,AB; AC,16832356,PubMed,10.1038/ng1839,Friesen et al. (2006) Nature Genetics 38:953-956,roliver@murdoch.edu.au,Tested on Tsn1 wheat,Friesen et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1245,PHI:1082,UniProt,Q00LS5,EMBL,ABD59786,,,,CpkA,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),,,,,calcium/calmodulin-dependent kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,"reduced on complex media, none on minimal media",slightly reduced,,,,,,,,,gene disruption,,RO,AB; AC,17020577,PubMed,10.1111/j.1365-2958.2006.05380.x,Solomon et al. (2006) Mol Microbiol. 62(2):367-81,psolomon@murdoch.edu.au,Not required for lesion development but required for sporulation after infection,Solomon et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1246,PHI:1083,UniProt,A9Z1V6,EMBL,ABD59787,,,,CpkB,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),,,,,calcium/calmodulin-dependent kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene deletion,,RO,AB; AC,17020577,PubMed,10.1111/j.1365-2958.2006.05380.x,Solomon et al. (2006) Mol Microbiol. 62(2):367-81,psolomon@murdoch.edu.au,,Solomon et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1247,PHI:1084,UniProt,Q0UGB6,Broad,SNOG_09198,,,,CpkC,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),,,,,calcium/calmodulin-dependent kinase,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,RO,AB; AC,17020577,PubMed,10.1111/j.1365-2958.2006.05380.x,Solomon et al. (2006) Mol Microbiol. 62(2):367-81,psolomon@murdoch.edu.au,Delayed lesion development and sporulation during infection. Unaffected during growth in planta.,Solomon et al.,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1248,PHI:1085,UniProt,Q6Y392,EMBL,AAO31597,,,,Ptr2,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),,,,,di/tripeptide transporter,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,RO,AB; AC,,Not in PubMed,10.1016/j.pmpp.2003.12.003,"Solomon et al (2004) Physiol. Mol. Plant Pathology 63, 191-199",roliver@central.murdoch.edu.au,,Solomon et al.,2003,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1249,PHI:1086,UniProt,I1RA89,Broad,FGSG_00416,,,,FGSG_00416,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,putative major facilitator superfamily,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,wild type,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 5' of ORF start,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1250,PHI:1087,UniProt,I1RKU0,Broad,FGSG_04510,,,,FGSG_04510,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,unknown,,,,unaffected pathogenicity,,,,,,,perithecial initials only,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is in ORF,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1251,PHI:1088,UniProt,A0A098DMH0,EMBL,FGRAMPH1_01T26337,,,,FGSG_09759,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,putative cation efflux family,,,,unaffected pathogenicity,,,,,,,decreased,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 3' of ORF end,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1252,PHI:1089,UniProt,I1RFR2,Broad,FGSG_02549,,,,FGSG_02549,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,putative phosphoglycerate mutase family,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,wild type,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 5' of ORF start,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1253,PHI:1090,UniProt,A0A0E0RVW9,EMBL,FGRAMPH1_01T07179,,,,FGSG_10057,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,wild type,reduced,,,,,,,,,gene disruption; gene complementation,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is in ORF,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1254,PHI:1091,UniProt,I1RWQ7,Broad,FGSG_08737,,,,FGSG_08737,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,unknown,,,,unaffected pathogenicity,,,,,,,decreased,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 3' of ORF end,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1255,PHI:1092,UniProt,I1S7D0,Broad,FGSG_12753,,,,FGSG_12753,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,wild type,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 3' of ORF end,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1256,PHI:1093,UniProt,I1REI8,Broad,FGSG_02077,,,,FGSG_02077,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,wild type,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 5' of ORF start,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1257,PHI:1094,UniProt,I1RL30,Broad,FGSG_04610,,,,FGSG_04610,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,similar to maltose permease,,,,unaffected pathogenicity,,,,,,,perithecial initials only,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 5' of ORF start,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1258,PHI:1095,UniProt,I1RZQ3,Broad,FGSG_09905,,,,FGSG_09905,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,unknown,,,,unaffected pathogenicity,,,,,,,perithecial initials only,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 5' of ORF start,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1259,PHI:1096,UniProt,I1RSE4,Broad,FGSG_07062,,,,FGSG_07062,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,unknown,,,,unaffected pathogenicity,,,,,,,,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 5' of ORF start,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1260,PHI:1097,UniProt,I1RE92,Broad,FGSG_01974,,,,FGSG_01974,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,similar to HET-C2 glycolipid transfer protein,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,,wild type,,,,,,,,,gene disruption; gene complementation,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 5' of ORF start,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1261,PHI:1098,UniProt,I1S5A1,Broad,FGSG_12019,,,,FGSG_12019,,,,,,,5518,Fusarium graminearum,,Fg 820,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,unknown,"GO:0009405, IMP",GO,,reduced virulence,,,,,,,wild type,wild type,,,,,,,,,gene disruption,,,AB; AC,18926918,PubMed,10.1016/j.fgb.2008.09.004,Dufresne et al. (2008) Fungal Genetics and Biology 45(12): 1552-1561,marie.dufresne@igmors.u-psud.fr,Transposon insertion is 5' of ORF start,Dufresne et al.,2008,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1262,PHI:1101,UniProt,J9MB32,Broad,FOXG_00076,,,,FOXG_00076,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4082,Solanum peruvianum (related: peruvian tomato),,,,,putative Zn finger transcription factor,GO:0009405,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,AB,19161356,PubMed,10.1111/J.1364-3703.2008.00512.X,,ge1hedic@uco.es,,Lopez_Berges et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1263,PHI:1101,UniProt,J9MB32,Broad,FOXG_00076,,,,FOXG_00076,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,3750,Malus domestica (related: apple),,,,,putative Zn finger transcription factor,GO:0009405,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,AB,19161356,PubMed,10.1111/J.1364-3703.2008.00512.X,,ge1hedic@uco.es,,Lopez_Berges et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1264,PHI:1103,UniProt,J9MHC1,Broad,FOXG_02277,,,,FOXG_02277,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4082,Solanum peruvianum (related: peruvian tomato),,,,,putative MeaB homologue,GO:0009405,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,19161356,PubMed,10.1111/J.1364-3703.2008.00512.X,,ge1hedic@uco.es,,Lopez_Berges et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1265,PHI:1103,UniProt,J9MHC1,Broad,FOXG_02277,,,,FOXG_02277,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,3750,Malus domestica (related: apple),,,,,putative MeaB homologue,GO:0009405,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,19161356,PubMed,10.1111/J.1364-3703.2008.00512.X,,ge1hedic@uco.es,,Lopez_Berges et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1266,PHI:1105,UniProt,J9N0G7,Broad,FOXG_08661,,,,FOXG_08661,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4082,Solanum peruvianum (related: peruvian tomato),,,,,conserved hypothetical protein,GO:0009405,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,19161356,PubMed,10.1111/J.1364-3703.2008.00512.X,,ge1hedic@uco.es,,Lopez_Berges et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1267,PHI:1105,UniProt,J9N0G7,Broad,FOXG_08661,,,,FOXG_08661,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,3750,Malus domestica (related: apple),,,,,conserved hypothetical protein,GO:0009405,GO,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AB,19161356,PubMed,10.1111/J.1364-3703.2008.00512.X,,ge1hedic@uco.es,,Lopez_Berges et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1268,PHI:1107,UniProt,J9MAX2,Broad,FOXG_00016,,,,FOXG_00016,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4082,Solanum peruvianum (related: peruvian tomato),,,,,homology to velvet family,GO:0009405,GO,,reduced virulence,,,,,,,,reduced aerial mycelium,,,,,,,,,gene disruption; gene complementation,,,AB,19161356,PubMed,10.1111/J.1364-3703.2008.00512.X,,ge1hedic@uco.es,,Lopez_Berges et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1269,PHI:1108,UniProt,J9MAX2,Broad,FOXG_00016,,,,FOXG_00016,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,3750,Malus domestica (related: apple),,,,,homology to velvet family,GO:0009405,GO,,reduced virulence,,,,,,,,reduced aerial mycelium,,,,,,,,,gene disruption; gene complementation,,,AB,19161356,PubMed,10.1111/J.1364-3703.2008.00512.X,,ge1hedic@uco.es,,Lopez_Berges et al.,2009,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1270,PHI:1109,UniProt,P30599,GenBank,um04290,,,,chs2,,,,,,,5270,Ustilago maydis,,FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,chitin synthase,GO:0009405,GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,AB,16314447,PubMed,10.1105/tpc.105.037341,,gero.steinberg@staff.uni-marburg.de,,Weber et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1271,PHI:1110,UniProt,Q99126,GenBank,um10120,,,,chs3,,,,,,,5270,Ustilago maydis,,FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,chitin synthase,GO:0009405,GO,,reduced virulence,yes (reduced),,,,,,,,,,,,,,,,gene deletion,,,AB,16314447,PubMed,10.1105/tpc.105.037341,,gero.steinberg@staff.uni-marburg.de,,Weber et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1272,PHI:1111,UniProt,Q99127,GenBank,um10117,,,,chs4,,,,,,,5270,Ustilago maydis,,FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,chitin synthase,GO:0009405,GO,,reduced virulence,yes (reduced),,,,,,,,,,,,,,,,gene deletion,,,AB,16314447,PubMed,10.1105/tpc.105.037341,,gero.steinberg@staff.uni-marburg.de,,Weber et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1273,PHI:1112,UniProt,Q4PAM3,GenBank,um02840,,,,chs5,,,,,,,5270,Ustilago maydis,,FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,chitin synthase,,,,unaffected pathogenicity,yes (reduced),,,,,,,yeast-like cells defective,,,,,,,,,gene deletion; gene complementation,,,AB,16314447,PubMed,10.1105/tpc.105.037341,,gero.steinberg@staff.uni-marburg.de,,Weber et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1274,PHI:1113,UniProt,Q4P333,GenBank,um05480,,,,chs7,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,chitin synthase,GO:0009405,GO,,loss of pathogenicity,yes (reduced),,,,,,,yeast-like cells defective; defective hyphal growth,,,,,,,,,gene deletion; gene complementation,,,AB,16314447,PubMed,10.1105/tpc.105.037341,,gero.steinberg@staff.uni-marburg.de,,Weber et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1275,PHI:1114,UniProt,Q4P9K9,EMBL,EAK84434,,,,mcs1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,chitin synthase,GO:0009405,GO,,loss of pathogenicity,,,,,,,,yeast-like cells thick,,,,,,,,,gene deletion,,,AB,16314447,PubMed,10.1105/tpc.105.037341,,gero.steinberg@staff.uni-marburg.de,,Weber et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1276,PHI:1115,UniProt,P30598,GenBank,um10718,,,,chs1,,,,,,,5270,Ustilago maydis,,,smut (corn),monocots,4577,Zea mays (related: maize),,,,,chitin synthase,,,,unaffected pathogenicity,yes (reduced),,,,,,,yeast-like cells slightly short,,,,,,,,,gene disruption,,,AB,16314447,PubMed,10.1105/tpc.105.037341,,gero.steinberg@staff.uni-marburg.de,,Weber et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1277,PHI:1116,UniProt,O13395,GenBank,um10367,,,,chs6,,,,,,,5270,Ustilago maydis,559306,FB1,smut (corn),monocots,4577,Zea mays (related: maize),,,,,chitin synthase,GO:0009405,GO,,loss of pathogenicity,yes (reduced),,,,,,,yeast-like cells thick,,,,,,,,,gene disruption; gene complementation,,,AB,16314447,PubMed,10.1105/tpc.105.037341,,gero.steinberg@staff.uni-marburg.de,,Weber et al,2006,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1278,PHI:1117,UniProt,Q4P8W4,GenBank,um03449,,,,sep3,,,,,,,5270,Ustilago maydis,237631,518; 521,smut (corn),monocots,4577,Zea mays (related: maize),,,,,septin,GO:0009405,GO,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,,AB,16339722,PubMed,10.1128/EC.4.12.2044-2056.2005,,kronstad@interchange.ubc.ca,Required for normal cellular morphology and the division of budding haploid cells.Required for lipid-induced filamentous growth in culture. Influences the differentiation of hyphae into teliospores and teliospore germination.,Boyce et al,2005,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1279,PHI:1118,UniProt,Q4PGI9,GenBank,um00774,,,,Rac1,,,,,,,5270,Ustilago maydis,559306,FB1; Bub8,smut (corn),monocots,4577,Zea mays (related: maize),,,,,small GTPase,GO:0009405,GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB,16390450,PubMed,10.1111/j.1365-2958.2005.04952.x,,boelker@staff.uni-marburg.de,Cell division altered. Impaired vaucole and filament formation,Mahlert et al,2005,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1280,PHI:1119,UniProt,Q8NJX2,EMBL,AF463452,,,,Cdc42,,,,,,,5270,Ustilago maydis,559306,FB1; Bub8,smut (corn),monocots,4577,Zea mays (related: maize),,,,,small GTPase,GO:0009405,GO,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion,,,AB,16390450,PubMed,10.1111/j.1365-2958.2005.04952.x,#LAST PHI-base 3.3 ENTRY#,boelker@staff.uni-marburg.de,Failure to separate after cytokinesis,Mahlert et al,2005,,,PHI-base Vers.3.3,2009-05-04,RRes,,,,,,,,,,,,,
,,Record 1281,PHI:1131,UniProt,A4F4L2,EMBL,CAJ90695,,,v23.1.3,AvrLm6,,,,,,,5022,Leptosphaeria maculans,,v23.1.3,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene complementation,,BH,AC,17427816,PubMed,10.1094/MPMI-20-4-0459,Fudal et al. (2007). Mol. Plant Microbe Interact. 20(4):459-470,rouxel@versailles.inra.fr,Functional complementation assay. Agro-mediated transformation of AvrLm6 into virulent strain restored avirulence.,Fudal et al.,2007,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1282,PHI:1132,UniProt,B9ZUL0,EMBL,CAQ53119,,,v23.1.3,AvrLm4-7,,,,,,,5022,Leptosphaeria maculans,,v23.1.3,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,BH,AC,19170874,PubMed,10.1111/j.1365-2958.2008.06547.x,Parlange et al. (2009). Mol. Microbiol. 71(4):851-63,rouxel@versailles.inra.fr,,Parlange et al.,2009,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1283,PHI:1133,UniProt,B9DR51,EMBL,AM941452,,,v23.1.3,Lmepi,,,,,,,5022,Leptosphaeria maculans,,v23.1.3,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,UDP-4-galactose epimerase,,,Leloir pathway involved in galactose metabolism,loss of pathogenicity,,,,yes,,,,,,,,,,,,,gene disruption; gene complementation,,BH,AC,19445597,PubMed,10.1094/MPMI-22-6-0725,Remy et al. (2009). Mol. Plant Microbe Interact. 22(6):725-36.,rouxel@versailles.inra.fr,,Remy et al.,2009,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1284,PHI:1134,UniProt,B0LLU1,EMBL,EU266496,,,IBCN18,ipa,,,,,,,5022,Leptosphaeria maculans,,ICBN 18,Phoma stem canker,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,unknown,,,,increased virulence (hypervirulence),,,yes (increased),,,,,,,,,,,,,,gene disruption; gene complementation,,BH,AC,19825554,PubMed,10.1093/mp/ssn014,Elliott et al. (2008). Mol. Plant 1(3):471-81.,bhowlett@unimelb.edu.au,Increased stomatal penetration and host defence responses; No effect on Brassica napus,Elliott et al.,2008,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1285,PHI:1135,UniProt,C6KED4,EMBL,GQ183869,,,IBCN18,LmIFRD,,,,,,,5022,Leptosphaeria maculans,,ICBN 18,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),,,,,IFRD domain-containing protein,,,,loss of pathogenicity,,,,,,reduced,,,aberrant (slow germination rate),,,,,,,,gene disruption,,BH,AC,19539773,PubMed,10.1016/j.fgb.2009.06.004,Van de Wouw et al. (2009). Fungal Genetics and Biology 46(9):695-706.,bhowlett@unimelb.edu.au,,Van de Wouw et al.,2009,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1286,PHI:1136,UniProt,B2SRG7,EMBL,ACD57936,,,PXO99A,raxR,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,two component response regulator activity required for Ax21 (synonym: AvrXa21) activity,"GO:0000160, IEA; GO:0006355, IEA; GO:0003677, IEA; GO:0000156, IEA",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,PR,AC,15195943,PubMed,10.1094/MPMI.2004.17.6.602,"Burdman et al., (2004). Mol Plant Microbe Interact.17(6):602-12.",pcronald@ucdavis.edu,"Test on Oryza sativa containing Xa21 gene. Mutant partially lost ax21 (synonym: avrxa21) activity. RaxH/RaxR system required for wt AvrXa21 activity. Caution paper retraction of related Science paper Lee et al., 2009 due to strain mix up PHI:1146",Burdman et al.,2004,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1287,PHI:1137,UniProt,B2SRG8,EMBL,ACD57937,,,PXO99A,raxH,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,two component sensor kinase activity required for Ax21 (synonym: AvrXa21) activity,"GO:0007165, IEA; GO:0018106, IEA; GO:0016310, IEA; GO:0000155, IEA; GO:0004673, IEA; GO:0016772, IEA; GO:0004871, IEA; GO:0016740, IEA; GO:0005524, IEA; GO:0001602, IEA",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,PR,AC,15195943,PubMed,10.1094/MPMI.2004.17.6.602,"Burdman et al., (2004). Mol Plant Microbe Interact.17(6):602-12.",pcronald@ucdavis.edu,"Test on Oryza sativa containing Xa21 gene. Mutant partially lost ax21 (synonym: avrxa21) activity. RaxH/RaxR system required for wt AvrXa21 activity. Caution paper retraction of related Science paper Lee et al., 2009 due to strain mix up PHI:1146",Burdman et al.,2004,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1288,PHI:1138,UniProt,B2SI03,EMBL,ACD60245,,,PXO99A,raxP (cysD),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,sulfate adenylyltransferase (ATP) required for Ax21 activity,"GO:0008152, IEA; GO:0019419, IEA; GO:0004781, IEA; GO:0016779, IEA; GO:0005524, IEA; GO:0016740, IEA; GO:0000166, IEA",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,PR,AC,11967067,PubMed,10.1046/j.1365-2958.2002.02862.x,"Shen et al., (2002). Mol Microbiol. 44(1):37-48.",pcronald@ucdavis.edu,"Test on Oryza sativa containing Xa21 gene. Mutant partially lost ax21 (synonym: avrxa21) activity. Required for wt AvrXa21 activity. Caution paper retraction of related Science paper Lee et al., 2009 due to strain mix up PHI:1146",Shen et al.,2002,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1289,PHI:1139,UniProt,B2SI02,EMBL,ACD60244,,,PXO99A,raxQ,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,adenylylsulfate kinase protein required for Ax21 (synonym: AvrXa21) activity,"GO:0000103, IEA; GO:0005524, IEA; GO:0005525, IEA; GO:0016301, IEA; GO:0016772, IEA; GO:0016740, IEA; GO:0016301, IEA; GO:0016779, IEA; GO:0003924, IEA; GO:0000166, IEA",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,PR,AC,11967067,PubMed,10.1046/j.1365-2958.2002.02862.x,"Shen et al., (2002). Mol Microbiol. 44(1):37-48.",pcronald@ucdavis.edu,"Test on Oryza sativa containing Xa21 gene. Mutant partially lost ax21 (synonym: avrxa21) activity. Required for wt AvrXa21 activity. Caution paper retraction of related Science paper Lee et al., 2009 due to strain mix up PHI:1146",Shen et al.,2002,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1290,PHI:1140,UniProt,B2SRG0,EMBL,ACD57929,,,PXO99A,raxA,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,membrane fusion transporter protein required for Ax21 (synonym: AvrXa21) activity,"GO:0009306, IEA; GO:0008565, IEA; GO:0016020, IEA",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,PR,AC,15195942,PubMed,10.1094/MPMI.2004.17.6.593,"da Silva et al., (2004). Mol Plant Microbe Interact. 17(6):593-601",pcronald@ucdavis.edu,"Test on Oryza sativa containing Xa21 gene. Mutant partially lost ax21 (synonym: avrxa21) activity. Required for wt AvrXa21 activity. Caution paper retraction of related Science paper Lee et al., 2009 due to strain mix up PHI:1146",da Silva et al.,2004,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1291,PHI:1141,UniProt,B2SRG1,EMBL,ACD57930,,,PXO99A,raxB,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,ATP-binding transporter protein required for Ax21 activity,"GO:0016021, IEA; GO:0006508, IEA; GO:0055085, IEA; GO:0006810, IEA; GO:0005524, IEA; GO:0008233, IEA; GO:0017111, IEA; GO:0000166, IEA; GO:0042626, IEA; GO:0016887, IEA",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,PR,AC,15195942,PubMed,10.1094/MPMI.2004.17.6.593,"da Silva et al., (2004). Mol Plant Microbe Interact. 17(6):593-601",pcronald@ucdavis.edu,"Test on Oryza sativa containing Xa21 gene. Mutant partially lost ax21 (synonym: avrxa21) activity. Required for wt AvrXa21 activity. Caution paper retraction of related Science paper Lee et al., 2009 due to strain mix up PHI:1146",da Silva et al.,2004,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1292,PHI:1142,UniProt,B2SNI2,EMBL,ACD60904,,,PXO99A,raxC,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,outer membrane protein required for Ax21 (synonym: AvrXa21) activity,"GO:0006810, IEA; GO:0015031, IEA; GO:0005215, IEA; GO:0019867, IEA",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,PR,AC,15195942,PubMed,10.1094/MPMI.2004.17.6.593,"da Silva et al., (2004). Mol Plant Microbe Interact. 17(6):593-601",pcronald@ucdavis.edu,"Test on Oryza sativa containing Xa21 gene. Mutant partially lost ax21 (synonym: avrxa21) activity. Required for wt AvrXa21 activity. Caution paper retraction of related Science paper Lee et al., 2009 due to strain mix up PHI:1146",da Silva et al.,2004,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1293,PHI:1143,UniProt,B2SRF9,EMBL,ACD57928,,,PXO99A,raxST,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,sulfotransferase required for Ax21 (synonym: AvrXa21) activity,"GO:0016740, IEA",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,PR,AC,15195942,PubMed,10.1094/MPMI.2004.17.6.593,"da Silva et al., (2004). Mol Plant Microbe Interact. 17(6):593-601",pcronald@ucdavis.edu,"Test on Oryza sativa containing Xa21 gene. Mutant partially lost ax21 (synonym: avrxa21) activity. Required for wt AvrXa21 activity. Caution paper retraction of related Science paper Lee et al., 2009 due to strain mix up PHI:1146",da Silva et al.,2004,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1294,PHI:1144,UniProt,A4K9H6,EMBL,ACD61380,,,PXO99A,PhoP,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,two-component system response regulatory required for Ax21 (synonym: AvrXa21)activity,"GO:0006355, IEA; GO:0000160, IEA; GO:0000156, IEA; GO:0003677, IEA",GO,,reduced virulence,,,,,,,,,,,,,,,,,gene disruption; complementation; other evidence,,PR,AC,18203830,PubMed,10.1128/JB.01406-07,"Lee et al., (2008).J Bacteriol. 2008 Mar;190(6):2183-97",pcronald@ucdavis.edu,"Test on Oryza sativa containing Xa21 gene resulted in wt pathogenicity therefore either no effect on Avrxa21 activity or reduced overall virulence. Test on Oryza sativa lacking Xa21 gene resulted in reduced virulence therefore overall reduced virulence (mask any effect of mutant on AvrXa21 activity). Caution paper retraction of related Science paper Lee et al., 2009 due to strain mix up PHI:1146",Lee et al.,2006,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1295,PHI:1145,UniProt,A4K9H7,EMBL,ACD61379,,,PXO99A,PhoQ,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,two-component system sensor kinase required for Ax21 (synonym: AvrXa21) activity,"GO:0016310, IEA; GO:0000160, IEA; GO:0007165, IEA; GO:0018106, IEA; GO:0000155, IEA; GO:0004673, IEA; GO:0016740, IEA; GO:0005524, IEA; GO:0016772, IEA; GO:0004871, IEA; GO:0000166, IEA; GO:0016021, IEA; GO:0016020, IEA",GO,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene disruption; gene complementation,,PR,AC,18203830,PubMed,10.1128/JB.01406-07,"Lee et al., (2008).J Bacteriol. 2008 Mar;190(6):2183-97",pcronald@ucdavis.edu,"Test on Oryza sativa containing Xa21 gene. Mutant partially lost ax21 (synonym: avrxa21) activity. Required for wt AvrXa21 activity. Caution paper retraction of related Science paper Lee et al., 2009 due to strain mix up PHI:1146",Lee et al.,2006,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1296,PHI:1146,UniProt,B2SKA7,EMBL,ACD57244,,,PXO99A,Ax21 (synonym: AvrXa21),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,,activator of XA21-mediated immunity,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene disruption,,PR,AC,19892983,PubMed,10.1126/science.1173438,"Lee et al., (2009). Science 326(5954):850-3",pcronald@ucdavis.edu,Test on Oryza sativa containing Xa21 gene; Lost Ax21 (synonym: AvrXa21) activity PAPER RETRACTED strain mix up,Lee et al.,2009,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1297,PHI:1147,UniProt,Q5UIP5,EMBL,AAV33131,,,,AurR1,,,,,,,101028,Fusarium pseudograminearum,,IBT 1544,stem blight (barley),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,,regulator of aurofusarin biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene mutation: characterised,,DG,AC,15809006,PubMed,10.1016/j.fgb.2005.01.010,"Malz et al., (2005). Fungal Genetics and Biology 42(5):420-433",heg@kvl.dk,T-DNA insertion in promoter,Malz et al.,2005,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1298,PHI:1149,UniProt,F9XG32,Broad,FJ196447,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,R6-31,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: epoxiconazole: CHEBI:4811, CAS:133855-98-8; anti-infective: tebuconazole: CHEBI:81781, CAS:107534-96-3; anti-infective: prochloraz: CHEBI:8434, CAS:67747-09-5",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,Resistant to azole Y137F substitution (updated this curation from Table 1),Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1299,PHI:1150,UniProt,F9XG32,Broad,FJ196450,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,Berdun 4,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: epoxiconazole: CHEBI:4811, CAS:133855-98-8",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,Resistant to azole G460D substitution (updated this curation from Table 1),Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1300,PHI:1152,UniProt,F9XG32,Broad,FJ196453,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V209.10,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: epoxiconazole: CHEBI:4811, CAS:133855-98-8; anti-infective: tebuconazole: CHEBI:81781, CAS:107534-96-3",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole L50S, I381V, Y461H substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1301,PHI:1152,UniProt,F9XG32,Broad,FJ196453,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V209.10,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: prochloraz: CHEBI:8434, CAS:67747-09-5",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole L50S, I381V, Y461H substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1302,PHI:1153,UniProt,F9XG32,Broad,FJ196452,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V115.3,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: epoxiconazole: CHEBI:4811, CAS:133855-98-8; anti-infective: tebuconazole: CHEBI:81781, CAS:107534-96-3",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole L50S, I381V, Y461H substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1303,PHI:1153,UniProt,F9XG32,Broad,FJ196452,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V115.3,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: prochloraz: CHEBI:8434, CAS:67747-09-5",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole L50S, I381V, Y461H substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1304,PHI:1154,UniProt,F9XG32,Broad,FJ196451,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V103.9,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: epoxiconazole: CHEBI:4811, CAS:133855-98-8; anti-infective: prochloraz: CHEBI:8434, CAS:67747-09-5",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole L50S, V136A, Y461H substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1305,PHI:1155,UniProt,F9XG32,Broad,FJ196455,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V212.2,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: epoxiconazole: CHEBI:4811, CAS:133855-98-8; anti-infective: tebuconazole: CHEBI:81781, CAS:107534-96-3; anti-infective: prochloraz: CHEBI:8434, CAS:67747-09-5",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole V136A, S188N, deltaY459/G460 substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1306,PHI:1156,UniProt,F9XG32,Broad,FJ196454,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V209.9,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: epoxiconazole: CHEBI:4811, CAS:133855-98-8; anti-infective: tebuconazole: CHEBI:81781, CAS:107534-96-3; anti-infective: prochloraz: CHEBI:8434, CAS:67747-09-5",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole V136A, S188N, deltaY459/G460 substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1307,PHI:1157,UniProt,F9XG32,Broad,FJ196457,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V202.1,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: epoxiconazole: CHEBI:4811, CAS:133855-98-8; anti-infective: tebuconazole: CHEBI:81781, CAS:107534-96-3",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole L50S, S188N, A379G, I381V, deltaY459/G460, N513K substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1308,PHI:1157,UniProt,F9XG32,Broad,FJ196457,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V202.1,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: prochloraz: CHEBI:8434, CAS:67747-09-5",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole L50S, S188N, A379G, I381V, deltaY459/G460, N513K substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1309,PHI:1158,UniProt,F9XG32,Broad,FJ196456,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V214.7,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: resistance to chemical,,,,,,,,,,,,"anti-infective: epoxiconazole: CHEBI:4811, CAS:133855-98-8; anti-infective: tebuconazole: CHEBI:81781, CAS:107534-96-3",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole L50S, S188N, A379G, I381V, deltaY459/G460, N513K substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1310,PHI:1158,UniProt,F9XG32,Broad,FJ196456,,,IPO323,cyp51/erg11,chromosome 7,,,,,,1047171,Zymoseptoria tritici,,V214.7,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,eburicol 14 alpha-demethylase,,,sterol biosynthesis,chemistry target: sensitivity to chemical,,,,,,,,,,,,"anti-infective: prochloraz: CHEBI:8434, CAS:67747-09-5",,,,,biochemical analysis; gene mutation: characterised,,HJC,AC,19459949,PubMed,10.1111/j.1574-6968.2009.01645.x,Bean et al. (2009) FEMS Microbiol Lett. 296(2): 266-273,hans.cools@bbsrc.ac.uk,"Resistant to azole L50S, S188N, A379G, I381V, deltaY459/G460, N513K substitutions (updated this curation from Table 1)",Bean et al,2009,,,"Alayne Cuzick update (and again from table 1, 14_02_2019 some of HCJ previous notes incorrect)",2009-05-04,AC,,,,,,,,,,,,,
,,Record 1311,PHI:1159,UniProt,A5H456,EMBL,EF062310,,,IPO323,MgAtr7,chromosome 9,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,ATP-binding cassette (ABC) transporter,,,transport,chemistry target: sensitivity to chemical,,,,,,,,wild type,,,,"anti-infective: cyproconazole: CHEBI:81758, CAS:94361-06-5; anti-infective: iprodione: CHEBI:28909, CAS:36734-19-7; anti-infective: azoxystrobin: CHEBI:40909, CAS:131860-33-8",,,,,gene disruption,,HJC,AC,17379549,PubMed,10.1016/j.fgb.2007.02.001,Zwiers et al. (2007) Fungal Genetics and Biology 44(9):853-863,zweirs@cbs.knaw.nl,Unaffected in azole sensitivity compared to wild type,Zwiers et al,2007,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1312,PHI:1160,UniProt,Q9UW03,EMBL,CAB52402,,,B05.10,BcatrB,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,ATP-binding cassette (ABC) transporter,,,transport,chemistry target: sensitivity to chemical,,,,,,wild type,,,,,,"anti-infective: resveratrol: CHEBI:27881, CAS:501-36-0; anti-infective: fenpiclonil: CHEBI:34759, CAS:74738-17-3",,,,,gene deletion,,HJC,AC,11310744,PubMed,10.1002/ps.309,Vermeulen et al. (2001) Pest Management Science 57(5): 393-402,,Increased sensitivity to Resveratrol CHEBI:27881 CAS:501-36-0 and Fenpiclonil CHEBI:34759 CAS:74738-17-3.,Vermeulen et al,2001,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1313,PHI:1161,UniProt,A4ZGP3,Ensembl Genomes,Mycgr3G110044,,,IPO323,MgMfs1,,,,,,,1047171,Zymoseptoria tritici,,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),,,,,major facilitator superfamily transporter,,,transport,chemistry target: sensitivity to chemical,,,,,,,,,,,,anti-infective: strobilurin antifungal agent: CHEBI:86482,,,,,gene disruption,,HJC,AC,17107817,PubMed,10.1016/j.fgb.2006.09.007,Roohparvar et al. (2007) Fungal Genet Biol 44(5): 378-388,zweirs@cbs.knaw.nl,increased sensitivity to strobilurin fungicides CHEBI:86482,Roohparvar et al,2007,,,Alayne Cuzick update,2009-05-04,AC,,,,,,,,,,,,,
,,Record 1314,PHI:1161,UniProt,A4ZGP3,Ensembl Genomes,Mycgr3G110044,,,IPO323,MgMfs1,,,,,,,1047171,Zymoseptoria tritici,,IPO323,Septoria leaf blotch,monocots,4564,Triticum (related: wheat),cv. Obelisk,,,seedling,major facilitator superfamily transporter,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene disruption,,,AC,17107817,PubMed,10.1016/j.fgb.2006.09.007,Roohparvar et al. (2007) Fungal Genet Biol 44(5): 378-388,zweirs@cbs.knaw.nl,,Roohparvar et al,2007,,,,2017-07-07,AC,,,,,,,,,,,,,
,,Record 1315,PHI:1162,UniProt,I1RJS3,Broad,FGSG_04105,,,PH-1,BDM1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Bess,,,spike,phosphoducin-like protein; modulator of downstream signalling from G-abg complexes.,,,G protein signalling,reduced virulence,,,,,,reduced,defective,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22044756,PubMed,10.1111/j.1364-3703.2011.00758.x,,bbluhm@uark.edu,"mycotoxin.don.in_vivo{maize,wheat}.(""Reduced"")",Horevaj,2012,,,,2009-05-04,MU,"Bluhm, Burton",,,,,,,,,,,,
,,Record 1316,PHI:1162,UniProt,I1RJS3,Broad,FGSG_04105,,,PH-1,BDM1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 33D47,,,corn silk,,,,,reduced virulence,,,,,,reduced,defective,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22044756,PubMed,10.1111/j.1364-3703.2011.00758.x,,bbluhm@uark.edu,"mycotoxin.don.in_vivo{maize,wheat}.(""Reduced"")",Horevaj,2012,,,,2009-05-04,MU,"Bluhm, Burton",,,,,,,,,,,,
,,Record 1317,PHI:1162,UniProt,I1RJS3,Broad,FGSG_04105,,,PH-1,BDM1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 33D47,,,stem,,,,,reduced virulence,,,,,,reduced,defective,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22044756,PubMed,10.1111/j.1364-3703.2011.00758.x,,bbluhm@uark.edu,"mycotoxin.don.in_vivo{maize,wheat}.(""Reduced"")",Horevaj,2012,,,,2009-05-04,MU,"Bluhm, Burton",,,,,,,,,,,,
,,Record 1318,PHI:1162,UniProt,I1RJS3,Broad,FGSG_04105,,,PH-1,BDM1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 33D47,,,kernel,,,,,unaffected pathogenicity,,,,,,reduced,defective,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22044756,PubMed,10.1111/j.1364-3703.2011.00758.x,,bbluhm@uark.edu,"mycotoxin.don.in_vivo{maize,wheat}.(""Reduced"")",Horevaj,2012,,,,2009-05-04,MU,"Bluhm, Burton",,,,,,,,,,,,
,,Record 1319,PHI:1163,UniProt,A0A0E0RVW9,EMBL,FGRAMPH1_01T07179,,,PH-1,ERB1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Thassos,,,spike,transcription factor Zn(II)2Cys6 domain,,,,reduced virulence,,,,,,reduced,,reduced,increased,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,21830952,PubMed,10.1094/MPMI-06-11-0158,,dztang@genetics.ac.cn,mutants produce more pigments,Zhao,2011,,,,2009-05-04,MU,"Tang, Dingzhong",,,,,,,,,,,,
,,Record 1320,PHI:1164,UniProt,A0A098DG50,EMBL,FGRAMPH1_01T11255,,,PH-1,RRG1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zimai 1,,,spike,response regulator HOG pathway,,,HOG pathway,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,MU,MU,21535349,PubMed,10.1111/j.1364-3703.2010.00684.x,,zhma@zju.edu.cn,mutant more resistant to dicarboximide iprodione and phenylpyrrole fungicides fludioxonil; increased sensitivities to osmotic stressors. enhanced pigmentation on PDA. Mycotoxin.DON.in_vitro{wheat_kernels}.reduced,Jiang,2011,,,,2009-05-04,MU,"Ma, Zhonghua",,,,,,,,,,,,
,,Record 1321,PHI:1164,UniProt,A0A098DG50,EMBL,FGRAMPH1_01T11255,,,PH-1,SSK1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,histidine kinase two-component response regulator,,,,reduced virulence,,,,,,,aberrant,,,,,,,,,,gene deletion: partial; gene complementation,,MU,MU,21037181,PubMed,10.1128/EC.00150-10,,bgt1@cornell.edu.,,Oide,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1322,PHI:1165,UniProt,I1RQL4,Broad,FGSG_06359.3,,,PH-1,RRG2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4566,Triticum aestivum x Triticum timopheevi (related: common wheat x sanduri wheat),cv. Zimai 2,,,spike,response regulator HOG pathway,,,HOG pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: partial,,MU,MU,21535349,PubMed,10.1111/j.1364-3703.2010.00684.x,,zhma@zju.edu.cn,enhanced pigmentation on PDA/ increased sensitivity to oxidative stress generated by H2O,Jiang,2011,,,,2009-05-04,MU,"Ma, Zhonghua",,,,,,,,,,,,
,,Record 1323,PHI:1166,UniProt,I1RFN8,Broad,FGSG_02519,,,PH-1,ATG15,,,,,,,5518,Fusarium graminearum,,8/1,Fusarium ear blight,monocots,4566,Triticum aestivum x Triticum timopheevi (related: common wheat x sanduri wheat),cv. Nandu,,,spike,autophagy-like lipase,,,autophagy nutrient recycling pathway,reduced virulence,,,,,,aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; heterologous expression,,MU,MU,21094265,PubMed,10.1016/j.fgb.2010.11.004,,schaefer@botanik.uni-hamburg.de,"mycotoxin.don.in_vivo{wheat}.(""Reduced"")",Nguyen,2011,,,,2009-05-04,MU,"Schaefer, W; Giese, H.",,,,,,,,,,,,
,,Record 1324,PHI:1167,UniProt,I1RY25,Broad,FGSG_09254,,,PH-1,NPC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4566,Triticum aestivum x Triticum timopheevi (related: common wheat x sanduri wheat),cv. Norm,,,spike,sterol trafficking,,,sterol trafficking,reduced virulence,,,,,,wild type,,reduced,,,,,,,,,gene deletion: full,,,MU,21397712,PubMed,10.1016/j.fgb.2011.03.001,,,Tebuconazole sensitive; increased ergosterol content accumulated in vacuole.,Breakspear,2011,,,,2009-05-04,MU,"Kistler C; Pasquali, M.",,,,,,,,,,,,
,,Record 1325,PHI:1168,UniProt,I1RCN2,Broad,FGSG_01353,,,PH-1,HDF1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 2,,,spike,class II histone deacetylase,"GO:0009405, IMP; GO:0044412; GO:0045482",GO,chromosome structure,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,21138346,PubMed,10.1094/MPMI-10-10-0233,,jinrong@purdue.edu,ScHOS2 is ortholog; HDF1 physically interacted with FTL1 in yeast two-hybrid assay. HDF1 expression highest in conidia compared to germlings and hypahe. 149 and 253 were down- and upregulated over fivehold in hdf1 mutant.. More tolerant to H2O2; mycotoxin.DON.reduced,Li,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1326,PHI:1169,UniProt,I1RKC4,Broad,FGSG_04324,,,PH-1,HDF2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 3,,,spike,class II histone deacetylase,"GO:0009405, IMP; GO:0044412; GO:0045483",GO,chromosome structure,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full,,MU,MU,21138346,PubMed,10.1094/MPMI-10-10-0233,,jinrong@purdue.edu,,Li,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1327,PHI:1170,UniProt,I1RNQ2,Broad,FGSG_05636,,,PH-1,HDF3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 4,,,spike,class II histone deacetylase,"GO:0009405, IMP; GO:0044412; GO:0045484",GO,chromosome structure,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,MU,MU,21138346,PubMed,10.1094/MPMI-10-10-0233,,jinrong@purdue.edu,,Li,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1328,PHI:1171,UniProt,I1RCN2,Broad,FGSG_01353,,,PH-1,HDF1,,,,,,PHI:1169,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 5,,,spike,class II histone deacetylase,"GO:0009405, IMP; GO:0044412; GO:0045485",GO,chromosome structure,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,MU,MU,21138346,PubMed,10.1094/MPMI-10-10-0233,,jinrong@purdue.edu,,Li,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1329,PHI:1172,UniProt,I1RKC4,Broad,FGSG_04324,,,PH-1,HDF2,,,,,,PHI:1168,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 6,,,spike,class II histone deacetylase,"GO:0009405, IMP; GO:0044412; GO:0045486",GO,chromosome structure,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,MU,MU,21138346,PubMed,10.1094/MPMI-10-10-0233,,jinrong@purdue.edu,,Li,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1330,PHI:1173,UniProt,I1RCN2,Broad,FGSG_01353,,,PH-1,HDF1,,,,,,PHI:1170,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 7,,,spike,class II histone deacetylase,"GO:0009405, IMP; GO:0044412; GO:0045487",GO,chromosome structure,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,MU,MU,21138346,PubMed,10.1094/MPMI-10-10-0233,,jinrong@purdue.edu,,Li,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1331,PHI:1174,UniProt,I1RNQ2,Broad,FGSG_05636,,,PH-1,HDF3,,,,,,PHI:1168,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 8,,,spike,class II histone deacetylase,"GO:0009405, IMP; GO:0044412; GO:0045488",GO,chromosome structure,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,MU,MU,21138346,PubMed,10.1094/MPMI-10-10-0233,,jinrong@purdue.edu,,Li,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1332,PHI:1175,UniProt,I1RKR8,Broad,FGSG_04484,,,PH-1,(Sc Srb10),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 9,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1333,PHI:1176,UniProt,I1RNG8,Broad,FGSG_05547,,,PH-1,(Sc Atg1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 10,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of RIM15,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1334,PHI:1177,UniProt,I1RKH9,Broad,FGSG_04382,,,PH-1,nrc-2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 11,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,aberrant,reduced,aberrant,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of CBK1,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1335,PHI:1178,UniProt,I1RW16,Broad,FGSG_08468,,,PH-1,(Sc Cdc28),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 12,,,spike,protein kinase,,,,reduced virulence,,,,,,increased,aberrant,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"homolog of Sc DBF2, DBF20",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1336,PHI:1179,UniProt,I1RZQ2,Broad,FGSG_09903,,,PH-1,(Sc Ste7),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 13,,,spike,protein kinase,,,,reduced virulence,,,,,,increased,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"homolog of ScTPK2, TPK3",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1337,PHI:1180,UniProt,A0A098DTI0,EMBL,FGRAMPH1_01T23545,,,PH-1,(Sc Sat4),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 14,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,wild type,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,mycotoxin.DON.reduced,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1338,PHI:1181,UniProt,I1RNY7,Broad,FGSG_05734,,,PH-1,(Sc Kic1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 15,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1339,PHI:1182,UniProt,A0A098DDT3,EMBL,FGRAMPH1_01T10563,,,PH-1,(Sc Mec1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 16,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,wild type,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of Sc SAK1,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1340,PHI:1183,UniProt,A0A1C3YKS2,EMBL,FGRAMPH1_01T23395,,,PH-1,(Sc Cmk1/Cmk2),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 17,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,aberrant,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1341,PHI:1184,UniProt,A0A098DGM6,EMBL,FGRAMPH1_01T10607,,,PH-1,(Sc Gin4-like),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 18,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1342,PHI:1185,UniProt,A0A1C3YJ96,EMBL,FGRAMPH1_01T07591,,,PH-1,(Sc Swe1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 19,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,aberrant,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,germination.germtube.abnormal,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1343,PHI:1186,UniProt,A0A1C3YJP1,EMBL,FGRAMPH1_01T07959,,,PH-1,(Sc Cdc15),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 20,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of Sc SAT4 (HAL4),Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1344,PHI:1187,UniProt,I1RWG6,Broad,FGSG_08635,,,PH-1,(Sc Dbf2/Dbf20),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 21,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of Sc PRR2,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1345,PHI:1188,UniProt,A0A1C3YIV6,EMBL,FGRAMPH1_01T04003,,,PH-1,(Sc Sak1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 22,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,aberrant,reduced,aberrant,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,germination.germtube.abnormal,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1346,PHI:1189,UniProt,I1RQN9,Broad,FGSG_06385,,,PH-1,MAP1 (related: GPMK1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 23,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScSWE1,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1347,PHI:1190,UniProt,I1RWL6,Broad,FGSG_08691,,,PH-1,(Sc Pbs2),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 24,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScCTK1,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1348,PHI:1191,UniProt,A0A0E0SIZ6,EMBL,FGRAMPH1_01T18031,,,PH-1,(Sc Ste11),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 25,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScCDC28 (CDC2),Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1349,PHI:1192,UniProt,I1RLX6,Broad,FGSG_04947,,,PH-1,(Sc Cak1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 26,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1350,PHI:1193,UniProt,I1RGD6,Broad,FGSG_02795,,,PH-1,(Sc Sky1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 27,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScSRB10,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1351,PHI:1194,UniProt,A0A0E0SGT0,EMBL,FGRAMPH1_01T24451,,,PH-1,FgMkk1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 28,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScCKA2,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1352,PHI:1195,UniProt,A0A098E1W1,EMBL,FGRAMPH1_01T20041,,,PH-1,(Sc Bck1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 29,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScYAK1,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1353,PHI:1196,UniProt,I1S0S6,Broad,FGSG_10313,,,PH-1,(Mgv1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 30,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"homolog of ScGSK3 (RIM11), MRK1",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1354,PHI:1197,UniProt,I1RZP6,Broad,FGSG_09897,,,PH-1,(Snf1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 31,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,aberrant,reduced,aberrant,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,germination.germtube.abnormal,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1355,PHI:1198,UniProt,I1RA81,Broad,FGSG_00408,,,PH-1,(Sc Ssk2/Ssk22),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 32,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1356,PHI:1199,UniProt,I1RSW5,Broad,FGSG_07251,,,PH-1,(Sc Tpk2),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 33,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,aberrant,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,germination.germtube.abnormal,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1357,PHI:1200,UniProt,I1RT36,Broad,FGSG_07329,,,PH-1,(Gsk3),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 34,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,germination.germtube.abnormal,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1358,PHI:1201,UniProt,Q4HYC1,Broad,FGSG_10037,,,PH-1,(Bud32),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 35,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,aberrant,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,germination.germtube.abnormal,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1359,PHI:1202,UniProt,A0A1C3YKT9,EMBL,FGRAMPH1_01T23603,,,PH-1,(Sc Cla4),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 36,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,wild type,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"homolog of ScCLA4, SKM1",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1360,PHI:1203,UniProt,I1S050,Broad,FGSG_10066,,,PH-1,(Sc Yck1/2/3),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 37,,,spike,protein kinase,,,,reduced virulence,,,,,,defective,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1361,PHI:1204,UniProt,I1RC85,Broad,FGSG_01188,,,PH-1,(Sc Cbk1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 38,,,spike,protein kinase,,,,reduced virulence,,,,,,defective,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"homolog of ScSPS1, KIC1",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1362,PHI:1205,UniProt,I1RA39,Broad,FGSG_00362,,,PH-1,(Sc CDC15),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 39,,,spike,protein kinase,,,,reduced virulence,,,,,,defective,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScCDC15,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1363,PHI:1206,UniProt,A0A1C3YN74,EMBL,FGRAMPH1_01T14345,,,PH-1,(Sp Prp4),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 40,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,germination.germtube.abnormal,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1364,PHI:1207,UniProt,A0A0E0SDV0,EMBL,FGRAMPH1_01T27499,,,PH-1,FgKin1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 41,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,aberrant,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScBCK1,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1365,PHI:1208,UniProt,I1RAE5,Broad,FGSG_00472,,,PH-1,(Sc Sch9),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 42,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,wild type,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1366,PHI:1209,UniProt,A0A1C3YJI0,EMBL,FGRAMPH1_01T16277,,,PH-1,FGSG_04770,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 43,,,spike,protein kinase,,,,reduced virulence,,,,,,increased,wild type,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1367,PHI:1210,UniProt,I1S077,Broad,FGSG_10095,,,PH-1,FGSG_10095,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 44,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,wild type,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1368,PHI:1211,UniProt,A0A1C3YKR8,EMBL,FGRAMPH1_01T23201,,,PH-1,(Sc Ctk1),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 45,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,defective,reduced,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1369,PHI:1212,UniProt,I1RCJ5,Broad,FGSG_01312,,,PH-1,(Sc Rim15),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 46,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,wild type,reduced,aberrant,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1370,PHI:1213,UniProt,I1RHM4,Broad,FGSG_03284,,,PH-1,FGSG_05586,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 120,,,spike,protein kinase,,,,reduced virulence,,,,,,increased,,reduced,,,,,,,,,gene deletion: full,,,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,,,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1371,PHI:1214,UniProt,I1RN54,Broad,FGSG_05418,,,PH-1,FGSG_07816,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 120,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,,increased,,,,,,,,,gene deletion: full,,,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,,,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1372,PHI:1215,UniProt,A0A0E0S1J9,Broad,FGSG_08906,,,PH-1,(Sc Prr2),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 48,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,wild type,increased,wild type,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScMEC1,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1373,PHI:1216,UniProt,I1RT48,Broad,FGSG_07344,,,PH-1,FGSG_07344,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 47,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,aberrant,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of Sp SPCC70.05C,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1374,PHI:1217,UniProt,I1S4P4,Broad,FGSG_11812,,,PH-1,FGSG_00792,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 120,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,,reduced,,,,,,,,,gene deletion: full,,,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,,,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1375,PHI:1218,UniProt,I1RAY2,Broad,FGSG_00677,,,PH-1,FGSG_00677,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 49,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1376,PHI:1219,UniProt,I1RC35,Broad,FGSG_01137,,,PH-1,FGSG_01137,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 50,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1377,PHI:1220,UniProt,I1RCF7,Broad,FGSG_01271,,,PH-1,FGSG_01271,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 51,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1378,PHI:1221,UniProt,I1RJM9,Broad,FGSG_04054,,,PH-1,FGSG_04054,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 52,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1379,PHI:1222,UniProt,I1RMV6,Broad,FGSG_05306,,,PH-1,FGSG_05306,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 53,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1380,PHI:1223,UniProt,I1RN31,Broad,FGSG_05393,,,PH-1,FGSG_05393,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 54,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2009-05-04,MU,,,,,,,,,,,,,
,,Record 1381,PHI:1224,UniProt,Q4IB89,Broad,FGSG_05519,,,PH-1,FGSG_05519,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 55,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1382,PHI:1225,UniProt,I1RP25,Broad,FGSG_05775,,,PH-1,FGSG_05775,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 56,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1383,PHI:1226,UniProt,I1RP88,Broad,FGSG_05845,,,PH-1,FGSG_05845,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 57,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1384,PHI:1227,UniProt,I1RPV7,Broad,FGSG_06089,,,PH-1,FGSG_06089,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 58,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScVPS15,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1385,PHI:1228,UniProt,I1RR00,Broad,FGSG_06502,,,PH-1,FGSG_06502,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 59,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1386,PHI:1229,UniProt,A0A0E0SDU8,EMBL,FGRAMPH1_01T22799,,,PH-1,FGSG_06637,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 60,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1387,PHI:1230,UniProt,V6RFV4,Broad,FGSG_06959,,,PH-1,FGSG_06959,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 61,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1388,PHI:1231,UniProt,Q4I5U9,Broad,FGSG_07409,,,PH-1,FGSG_07409,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 62,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1389,PHI:1232,UniProt,I1RTC2,Broad,FGSG_07423,,,PH-1,FGSG_07423,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 63,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1390,PHI:1233,UniProt,I1RUG2,Broad,FGSG_07855,,,PH-1,FGSG_07855,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 64,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1391,PHI:1234,UniProt,I1RV69,Broad,FGSG_08133,,,PH-1,FGSG_08133,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 65,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1392,PHI:1235,UniProt,A0A0E0S0W9,EMBL,FGRAMPH1_01T10683,,,PH-1,FGSG_08731,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 66,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScTEL1,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1393,PHI:1236,UniProt,I1RYF8,Broad,FGSG_09408,,,PH-1,FGSG_09408,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 67,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1394,PHI:1237,UniProt,I1RZ37,Broad,FGSG_09660,,,PH-1,FGSG_09660,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 68,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,homolog of ScTRA1,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1395,PHI:1238,UniProt,I1S1V3,Broad,FGSG_10725,,,PH-1,FGSG_10725,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 69,,,spike,protein kinase,,,,lethal,,,,,,,wild type,wild type,wild type,yes,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1396,PHI:1239,UniProt,A0A0E0RTV8,EMBL,FGRAMPH1_01T05757,,,PH-1,FGSG_02399,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 70,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1397,PHI:1240,UniProt,I1RWQ0,Broad,FGSG_08729,,,PH-1,FGSG_08729,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 71,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1398,PHI:1241,UniProt,I1RAE2,Broad,FGSG_00469,,,PH-1,FGSG_00469,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 72,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1399,PHI:1242,UniProt,A0A0E0S0J3,EMBL,FGRAMPH1_01T10431,,,PH-1,FGSG_08631,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 73,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1400,PHI:1243,UniProt,I1RBW7,Broad,FGSG_01058,,,PH-1,FGSG_01058,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 74,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,aberrant,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1401,PHI:1244,UniProt,I1RA20,Broad,FGSG_00337,,,PH-1,FGSG_00337,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 75,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,aberrant,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1402,PHI:1245,UniProt,I1RTL1,Broad,FGSG_07520,,,PH-1,FGSG_07520,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 76,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1403,PHI:1246,UniProt,I1RYQ5,Broad,FGSG_09513,,,PH-1,FGSG_09513,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 77,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1404,PHI:1247,UniProt,I1S0G8,Broad,FGSG_10196,,,PH-1,FGSG_10196,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 78,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1405,PHI:1248,UniProt,I1RRU2,Broad,FGSG_06832,,,PH-1,FGSG_06832,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 79,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1406,PHI:1249,UniProt,I1RB79,Broad,FGSG_00786,,,PH-1,FGSG_00786,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 80,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1407,PHI:1250,UniProt,I1RS33,Broad,FGSG_06940,,,PH-1,FGSG_06940,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 81,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1408,PHI:1251,UniProt,I1RD19,Broad,FGSG_01506,,,PH-1,FGSG_01506,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 82,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1409,PHI:1252,UniProt,A0A0E0SKT2,EMBL,FGRAMPH1_01T18709,,,PH-1,FGSG_05764,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 83,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1410,PHI:1253,UniProt,I1RS57,Broad,FGSG_06970,,,PH-1,FGSG_06970,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 84,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,defective,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1411,PHI:1254,UniProt,I1RDX3,Broad,FGSG_01842,,,PH-1,FGSG_01842,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 85,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1412,PHI:1255,UniProt,I1RQ67,Broad,FGSG_06206,,,PH-1,FGSG_06206,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 86,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1413,PHI:1256,UniProt,I1RAA6,Broad,FGSG_00433,,,PH-1,FGSG_00433,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 87,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1414,PHI:1257,UniProt,I1RSK0,Broad,FGSG_07121,,,PH-1,FGSG_07121,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 88,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1415,PHI:1258,UniProt,A0A0E0RU69,EMBL,FGRAMPH1_01T05979,,,PH-1,FGSG_12149,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 89,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1416,PHI:1259,UniProt,I1RNK3,Broad,FGSG_05586,,,PH-1,FGSG_05586,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 90,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1417,PHI:1260,UniProt,A0A1C3YLM4,EMBL,FGRAMPH1_01T25741,,,PH-1,FGSG_07816,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 91,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1418,PHI:1261,UniProt,A0A098DEV9,EMBL,FGRAMPH1_01T11431,,,PH-1,FGSG_02838,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 92,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1419,PHI:1262,UniProt,I1RQS1,Broad,FGSG_06420,,,PH-1,FGSG_06420,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 93,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1420,PHI:1263,UniProt,I1RB84,Broad,FGSG_00792,,,PH-1,FGSG_00792,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 94,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1421,PHI:1264,UniProt,I1RD70,Broad,FGSG_01559,,,PH-1,FGSG_01559,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 95,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1422,PHI:1265,UniProt,A0A098E3Q0,EMBL,FGRAMPH1_01T18183,,,PH-1,FGSG_05549,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 96,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1423,PHI:1266,UniProt,A0A0E0S2Z7,EMBL,FGRAMPH1_01T12137,,,PH-1,FGSG_03132,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 97,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1424,PHI:1267,UniProt,I1RKK7,Broad,FGSG_04418,,,PH-1,FGSG_04418,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 98,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1425,PHI:1268,UniProt,I1RN43,Broad,FGSG_05406,,,PH-1,FGSG_05406,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 99,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1426,PHI:1269,UniProt,I1RFK9,Broad,FGSG_02488,,,PH-1,FGSG_02488,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 100,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1427,PHI:1270,UniProt,A0A098DG04,EMBL,FGRAMPH1_01T12171,,,PH-1,FGSG_03146,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 101,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1428,PHI:1271,UniProt,I1R9J1,Broad,FGSG_00132,,,PH-1,FGSG_00132,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 102,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1429,PHI:1272,UniProt,A0A0E0SFK2,EMBL,FGRAMPH1_01T26955,,,PH-1,FGSG_09492,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 103,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1430,PHI:1273,UniProt,I1RCM6,Broad,FGSG_01347,,,PH-1,FGSG_01347,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 104,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,aberrant,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1431,PHI:1274,UniProt,I1RME6,Broad,FGSG_05135,,,PH-1,FGSG_05135,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 105,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1432,PHI:1275,UniProt,A0A098E0U9,EMBL,FGRAMPH1_01T19701,,,PH-1,FGSG_12887,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 106,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1433,PHI:1276,UniProt,A0A1C3YLX3,EMBL,FGRAMPH1_01T27811,,,PH-1,FGSG_09150,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 107,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1434,PHI:1277,UniProt,I1S5L1,Broad,FGSG_12132,,,PH-1,FGSG_12132,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 108,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1435,PHI:1278,UniProt,A0A098DW84,EMBL,FGRAMPH1_01T22251,,,PH-1,FGSG_11614,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 109,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1436,PHI:1279,UniProt,A0A1C3YL92,EMBL,FGRAMPH1_01T25541,,,PH-1,FGSG_07742,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 110,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1437,PHI:1280,UniProt,A0A098DUZ8,EMBL,FGRAMPH1_01T25547,,,PH-1,FGSG_07745,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 111,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1438,PHI:1281,UniProt,A0A098D624,EMBL,FGRAMPH1_01T05187,,,PH-1,FGSG_02153,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 112,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1439,PHI:1282,UniProt,I1S9H8,EMBL,FGRAMPH1_01T28025,,,PH-1,FGSG_13509,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 113,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1440,PHI:1283,UniProt,A0A098DAP9,EMBL,FGRAMPH1_01T08481,,,PH-1,FGSG_10591,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 114,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1441,PHI:1284,UniProt,I1RI73,Broad,FGSG_03499,,,PH-1,FGSG_03499,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 115,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1442,PHI:1285,UniProt,I1SAR3,Broad,FGSG_13944,,,PH-1,FGSG_13944,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 116,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1443,PHI:1286,UniProt,A0A1C3YL97,EMBL,FGRAMPH1_01T25731,,,PH-1,FGSG_07812,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 117,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1444,PHI:1287,UniProt,I1RT82,Broad,FGSG_07381,,,PH-1,FGSG_07381,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 118,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1445,PHI:1288,UniProt,I1RE83,Broad,FGSG_01963,,,PH-1,FGSG_01963,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 119,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,,Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1446,PHI:1289,UniProt,I1RKK5,Broad,FGSG_04416,,,PH-1,FGSG_04416,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm; cv. Xiaoyan 120,,,spike,protein kinase,,,,unaffected pathogenicity,,,,,,,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,MU,MU,22216007,PubMed,10.1371/journal.ppat.1002460,,jinrong@purdue.edu,"mycotoxin.don.in_vivo{wheat_ear}.(""reduced"")",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1447,PHI:1290,UniProt,I1S0A8,Broad,FGSG_10129,,,PH-1,STUA,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,transcriptional regulator,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion: full,,MU,MU,20879840,PubMed,10.1094/MPMI-03-10-0075,,erik.lysoe@bioforsk.no,"impaired spore production and reduced production of secondary metabolites; mycotoxin.don.{in_vitro+in_vivo}.wheat_ear.(""reduced"")",Lysoe,2011,,,,2010-05-04,MU,"Lysoe, E.",,,,,,,,,,,,
,,Record 1448,PHI:1291,UniProt,I1RRX4,Broad,FGSG_06874,,,PH-1,TOP1,4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Bobwhite,,,spike,topoisomerase I required to relac supercoilded DNA,,,,reduced virulence,,,,,,reduced,defective,aberrant,,no,,,,,,,gene deletion: full,,MU,MU,20367465,PubMed,10.1094/MPMI-23-5-0566,,kim.hammond-kosack@rothamsted.ac.uk,"growth rate altered at 28 C; mycotoxin.don.in_vitro.(""reduced"")",Baldwin,2010,,,,2010-05-04,MU,"Hammon-Kosack, K.",,,,,,,,,,,,
,,Record 1449,PHI:1292,UniProt,I1RD66,Broad,FGSG_01555,,,PH-1,ZIF1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,b-ZIP transcription factor unique to filamentous ascomycetes,,,,reduced virulence,,,,yes,,wild type,defective,wild type,,no,,,,,,,gene disruption; gene deletion; gene complementation,,MU,MU,20795857,PubMed,10.1094/MPMI-06-10-0129,,jingrong@purdue.edu,"mycotoxin.DON.reduced; forms small, empty perithecia",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1450,PHI:1292,UniProt,I1RD66,Broad,FGSG_01555,,,PH-1,ZIF1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,stem,b-ZIP transcription factor unique to filamentous ascomycetes,,,,reduced virulence,,,,yes,,wild type,defective,wild type,,no,,,,,,,gene disruption; gene deletion; gene complementation,,MU,MU,20795857,PubMed,10.1094/MPMI-06-10-0129,,jingrong@purdue.edu,"mycotoxin.DON.reduced; forms small, empty perithecia",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1451,PHI:1292,UniProt,I1RD66,Broad,FGSG_01555,,,PH-1,ZIF1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,corn silk,b-ZIP transcription factor unique to filamentous ascomycetes,,,,reduced virulence,,,,yes,,wild type,defective,wild type,,no,,,,,,,gene disruption; gene deletion; gene complementation,,MU,MU,20795857,PubMed,10.1094/MPMI-06-10-0129,,jingrong@purdue.edu,"mycotoxin.DON.reduced; forms small, empty perithecia",Wang,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1452,PHI:1293,UniProt,I1RK32,Broad,FGSG_04220,,,PH-1,GzAPSES001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1453,PHI:1294,UniProt,I1RMT5,Broad,FGSG_05283,,,PH-1,GzAPSES002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1454,PHI:1295,UniProt,I1S0A8,Broad,FGSG_10129,,,PH-1,FgStuA,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1455,PHI:1296,UniProt,I1S0Z2,Broad,FGSG_10384,,,PH-1,GzAPSES004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1456,PHI:1297,UniProt,I1RPU1,Broad,FGSG_06071,,,PH-1,GzAT001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1457,PHI:1298,UniProt,A0A0E0SB24,EMBL,FGRAMPH1_01T27171,,,PH-1,GzAT002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1458,PHI:1299,UniProt,I1RYN7,Broad,FGSG_09495,,,PH-1,GzAT003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1459,PHI:1300,UniProt,I1RAL4,Broad,FGSG_00545,,,PH-1,GzbHLH001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1460,PHI:1301,UniProt,I1RB45,Broad,FGSG_00750,,,PH-1,GzbHLH002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1461,PHI:1302,UniProt,I1RC37,Broad,FGSG_01139,,,PH-1,GzbHLH003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1462,PHI:1303,UniProt,A0A098D2S9,EMBL,FGRAMPH1_01T02913,,,PH-1,GzbHLH004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1463,PHI:1304,UniProt,I1RCJ0,Broad,FGSG_01307,,,PH-1,GzbHLH005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1464,PHI:1305,UniProt,I1RFN6,Broad,FGSG_02516,,,PH-1,GzbHLH006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1465,PHI:1306,UniProt,I1RGF4,Broad,FGSG_02814,,,PH-1,GzbHLH007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,increased,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1466,PHI:1307,UniProt,A0A0E0S3L8,EMBL,FGRAMPH1_01T12581,,,PH-1,GzbHLH008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1467,PHI:1308,UniProt,I1RJL0,Broad,FGSG_04035,,,PH-1,GzbHLH009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1468,PHI:1309,UniProt,I1RNI6,Broad,FGSG_05567,,,PH-1,GzbHLH010,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1469,PHI:1310,UniProt,I1RQC1,Broad,FGSG_06262,,,PH-1,GzbHLH011,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1470,PHI:1311,UniProt,I1RUA5,Broad,FGSG_07790,,,PH-1,GzbHLH012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1471,PHI:1312,UniProt,A0A1C3YM49,EMBL,FGRAMPH1_01T09867,,,PH-1,GzbHLH013,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1472,PHI:1313,UniProt,I1RY71,Broad,FGSG_09308,,,PH-1,GzbHLH014,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,increased,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1473,PHI:1314,UniProt,A0A098DA98,EMBL,FGRAMPH1_01T08111,,,PH-1,GzbHLH015,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1474,PHI:1315,UniProt,I1S491,Broad,FGSG_11658,,,PH-1,GzbHLH016,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1475,PHI:1316,UniProt,I1RBZ7,Broad,FGSG_01096,,,PH-1,GzBrom001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1476,PHI:1317,UniProt,I1RQE9,Broad,FGSG_06291,,,PH-1,GzBrom002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1477,PHI:1318,UniProt,I1RZM2,Broad,FGSG_09871,,,PH-1,GzBrom003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1478,PHI:1319,UniProt,I1RAI5,Broad,FGSG_00515,,,PH-1,GzbZIP001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,reduced,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1479,PHI:1320,UniProt,I1RD66,Broad,FGSG_01555,,,PH-1,ZIF1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1480,PHI:1321,UniProt,I1RFC6,Broad,FGSG_02398,,,PH-1,ZEB2,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1481,PHI:1322,UniProt,I1RG94,Broad,FGSG_02750,,,PH-1,GzbZIP004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1482,PHI:1323,UniProt,I1RGR6,Broad,FGSG_02939,,,PH-1,GzbZIP005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1483,PHI:1324,UniProt,I1RH05,Broad,FGSG_03040,,,PH-1,GzbZIP006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1484,PHI:1325,UniProt,I1RMI1,Broad,FGSG_05171,,,PH-1,GzbZIP007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1485,PHI:1326,UniProt,I1RPG1,Broad,FGSG_05930,,,PH-1,GzbZIP008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1486,PHI:1327,UniProt,I1RQS2,Broad,FGSG_06421,,,PH-1,GzbZIP009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1487,PHI:1328,UniProt,I1RRD2,Broad,FGSG_06651,,,PH-1,GzbZIP010,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,increased,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1488,PHI:1329,UniProt,I1RUA4,Broad,FGSG_07789,,,PH-1,GzbZIP011,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1489,PHI:1330,UniProt,A0A098DS24,EMBL,FGRAMPH1_01T25843,,,PH-1,GzbZIP012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1490,PHI:1331,UniProt,I1RWW4,Broad,FGSG_08800,,,PH-1,GzbZIP013,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1491,PHI:1332,UniProt,I1RXD5,Broad,FGSG_09001,,,PH-1,GzbZIP014,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1492,PHI:1333,UniProt,I1RY51,Broad,FGSG_09286,,,PH-1,GzbZIP015,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1493,PHI:1334,UniProt,I1RZI7,Broad,FGSG_09832,,,PH-1,GzbZIP016,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,aberrant,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1494,PHI:1335,UniProt,I1S0C0,Broad,FGSG_10142,,,PH-1,GzbZIP017,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1495,PHI:1336,UniProt,I1S462,Broad,FGSG_11623,,,PH-1,GzbZIP018,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1496,PHI:1337,UniProt,I1S674,Broad,FGSG_12345,,,PH-1,GzbZIP019,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1497,PHI:1338,UniProt,A0A1C3YMA5,EMBL,FGRAMPH1_01T10619,,,PH-1,GzbZIP020,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1498,PHI:1339,UniProt,A0A098DA75,EMBL,FGRAMPH1_01T08109,,,PH-1,GzbZIP021,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1499,PHI:1340,UniProt,I1S1E5,Broad,FGSG_10546,,,PH-1,GzbZIP022,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1500,PHI:1341,UniProt,A0A0E0RLK0,EMBL,FGRAMPH1_01T00647,,,PH-1,GzC2H001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1501,PHI:1342,UniProt,I1RA24,Broad,FGSG_00342,,,PH-1,GzC2H002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1502,PHI:1343,UniProt,I1RAF0,Broad,FGSG_00477,,,PH-1,GzC2H003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1503,PHI:1344,UniProt,I1RAQ0,Broad,FGSG_00584,,,PH-1,GzC2H004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1504,PHI:1345,UniProt,I1RAW2,Broad,FGSG_00653,,,PH-1,GzC2H005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1505,PHI:1346,UniProt,I1RB57,Broad,FGSG_00764,,,PH-1,GzC2H006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1506,PHI:1347,UniProt,I1RBT2,Broad,FGSG_01022,,,PH-1,GzC2H007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1507,PHI:1348,UniProt,I1RC07,Broad,FGSG_01106,,,PH-1,GzC2H008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1508,PHI:1349,UniProt,I1RCB1,Broad,FGSG_01214,,,PH-1,GzC2H009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1509,PHI:1350,UniProt,I1RCI2,Broad,FGSG_01298,,,PH-1,GzC2H010,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1510,PHI:1351,UniProt,I1RCJ3,Broad,FGSG_01310,,,PH-1,GzC2H011,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1511,PHI:1352,UniProt,I1RCK1,Broad,FGSG_01319,,,PH-1,GzC2H012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1512,PHI:1353,UniProt,I1RCM1,Broad,FGSG_01341,,,PH-1,GzC2H013,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1513,PHI:1354,UniProt,I1RCM9,Broad,FGSG_01350,,,PH-1,GzC2H014,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1514,PHI:1355,UniProt,I1RD84,Broad,FGSG_01576,,,PH-1,GzC2H015,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1515,PHI:1356,UniProt,I1RE06,Broad,FGSG_01877,,,PH-1,GzC2H016,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1516,PHI:1357,UniProt,I1RFY9,Broad,FGSG_02635,,,PH-1,GzC2H017,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1517,PHI:1358,UniProt,I1RG87,Broad,FGSG_02743,,,PH-1,GzC2H018,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1518,PHI:1359,UniProt,I1RGC9,Broad,FGSG_02788,,,PH-1,GzC2H019,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1519,PHI:1360,UniProt,I1RGE3,Broad,FGSG_02803,,,PH-1,GzC2H020,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1520,PHI:1361,UniProt,A0A1C3YMN8,EMBL,FGRAMPH1_01T12383,,,PH-1,GzC2H021,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1521,PHI:1362,UniProt,A0A0E0S4D3,EMBL,FGRAMPH1_01T13109,,,PH-1,TRI6,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1522,PHI:1363,UniProt,I1RJ74,Broad,FGSG_03881,,,PH-1,TRI15,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1523,PHI:1364,UniProt,I1RJQ3,Broad,FGSG_04083,,,PH-1,GzC2H024,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1524,PHI:1365,UniProt,I1RJQ4,Broad,FGSG_04084,,,PH-1,GzC2H025,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1525,PHI:1366,UniProt,I1RJV1,Broad,FGSG_04134,,,PH-1,GzCON7,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1526,PHI:1367,UniProt,I1RK94,Broad,FGSG_04288,,,PH-1,GzC2H028,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1527,PHI:1368,UniProt,I1RK97,Broad,FGSG_04293,,,PH-1,GzC2H029,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1528,PHI:1369,UniProt,I1RLS1,Broad,FGSG_04889,,,PH-1,GzC2H031,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1529,PHI:1370,UniProt,I1RLW2,Broad,FGSG_04932,,,PH-1,GzC2H032,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1530,PHI:1371,UniProt,I1RM60,Broad,FGSG_05041,,,PH-1,GzC2H034,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1531,PHI:1372,UniProt,I1RN03,Broad,FGSG_05359,,,PH-1,GzC2H035,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1532,PHI:1373,UniProt,A0A0E0SM05,EMBL,FGRAMPH1_01T17769,,,PH-1,GzC2H036,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1533,PHI:1374,UniProt,I1RN37,Broad,FGSG_05399,,,PH-1,GzC2H037,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1534,PHI:1375,UniProt,I1RPA0,Broad,FGSG_05857,,,PH-1,GzC2H038,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1535,PHI:1376,UniProt,I1RPM7,Broad,FGSG_06002,,,PH-1,GzC2H039,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1536,PHI:1377,UniProt,A0A1C3YKH4,EMBL,FGRAMPH1_01T19659,,,PH-1,GzC2H040,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1537,PHI:1378,UniProt,I1RQG9,Broad,FGSG_06311,,,PH-1,GzC2H041,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1538,PHI:1379,UniProt,I1RQS8,Broad,FGSG_06427,,,PH-1,GzC2H042,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1539,PHI:1380,UniProt,I1RRG4,Broad,FGSG_06684,,,PH-1,GzC2H043,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1540,PHI:1381,UniProt,I1RRI0,Broad,FGSG_06701,,,PH-1,GzC2H044,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1541,PHI:1382,UniProt,I1RRX1,Broad,FGSG_06871,,,PH-1,GzC2H045,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1542,PHI:1383,UniProt,I1RS27,Broad,FGSG_06934,,,PH-1,GzC2H046,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1543,PHI:1384,UniProt,A0A1C3YLC9,EMBL,FGRAMPH1_01T23837,,,PH-1,GzC2H047,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1544,PHI:1385,UniProt,A0A1C3YKW4,EMBL,FGRAMPH1_01T23899,,,PH-1,GzC2H048,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1545,PHI:1386,UniProt,A0A1C3YL03,EMBL,FGRAMPH1_01T24181,,,PH-1,GzC2H049,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1546,PHI:1387,UniProt,I1RT19,Broad,FGSG_07310,,,PH-1,GzBrlA,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1547,PHI:1388,UniProt,I1RT91,Broad,FGSG_07392,,,PH-1,GzC2H051,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1548,PHI:1389,UniProt,I1RTJ6,Broad,FGSG_07504,,,PH-1,GzC2H052,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1549,PHI:1390,UniProt,A0A0E0SBQ7,EMBL,FGRAMPH1_01T25523,,,PH-1,GzC2H053,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1550,PHI:1391,UniProt,I1RU55,Broad,FGSG_07737,,,PH-1,GzC2H054,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1551,PHI:1392,UniProt,I1RU67,Broad,FGSG_07751,,,PH-1,GzC2H055,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1552,PHI:1393,UniProt,I1RU69,Broad,FGSG_07753,,,PH-1,GzC2H056,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1553,PHI:1394,UniProt,I1RUL1,Broad,FGSG_07909,,,PH-1,GzC2H057,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1554,PHI:1395,UniProt,I1RUL5,Broad,FGSG_07914,,,PH-1,GzC2H058,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1555,PHI:1396,UniProt,I1RUM9,Broad,FGSG_07928,,,PH-1,GzC2H059,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,reduced,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1556,PHI:1397,UniProt,I1RUQ2,Broad,FGSG_07952,,,PH-1,GzC2H060,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1557,PHI:1398,UniProt,I1RV65,Broad,FGSG_08128,,,PH-1,GzC2H061,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1558,PHI:1399,UniProt,I1RV74,Broad,FGSG_08138,,,PH-1,GzC2H062,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1559,PHI:1400,UniProt,A0A098DDM6,EMBL,FGRAMPH1_01T09465,,,PH-1,GzC2H063,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1560,PHI:1401,UniProt,A0A098DCV0,EMBL,FGRAMPH1_01T09951,,,PH-1,GzC2H064,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1561,PHI:1402,UniProt,I1RWB8,Broad,FGSG_08582,,,PH-1,GzC2H065,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1562,PHI:1403,UniProt,I1RWF1,Broad,FGSG_08617,,,PH-1,GzC2H066,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,aberrant,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1563,PHI:1404,UniProt,I1RWH6,Broad,FGSG_08646,,,PH-1,GzC2H067,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1564,PHI:1405,UniProt,A0A098DFK7,EMBL,FGRAMPH1_01T10849,,,PH-1,GzC2H069,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1565,PHI:1406,UniProt,I1RX04,Broad,FGSG_08845,,,PH-1,GzC2H070,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1566,PHI:1407,UniProt,I1RX64,Broad,FGSG_08914,,,PH-1,GzC2H071,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1567,PHI:1408,UniProt,A0A098DXE8,EMBL,FGRAMPH1_01T28119,,,PH-1,GzC2H072,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1568,PHI:1409,UniProt,I1RYC3,Broad,FGSG_09368,,,PH-1,GzC2H075,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1569,PHI:1410,UniProt,I1RYG0,Broad,FGSG_09410,,,PH-1,GzC2H076,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1570,PHI:1411,UniProt,I1RZ11,Broad,FGSG_09629,,,PH-1,GzC2H078,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1571,PHI:1412,UniProt,I1RZ85,Broad,FGSG_09715,,,PH-1,GzC2H079,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1572,PHI:1413,UniProt,I1RZD4,Broad,FGSG_09770,,,PH-1,GzC2H080,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1573,PHI:1414,UniProt,I1RZL0,Broad,FGSG_09857,,,PH-1,GzC2H081,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1574,PHI:1415,UniProt,A0A1C3YJE6,EMBL,FGRAMPH1_01T07055,,,PH-1,GzC2H082,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1575,PHI:1416,UniProt,I1S0D8,Broad,FGSG_10162,,,PH-1,GzC2H083,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1576,PHI:1417,UniProt,I1S0W0,Broad,FGSG_10350,,,PH-1,GzC2H084,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1577,PHI:1418,UniProt,I1S0W9,Broad,FGSG_10360,,,PH-1,GzC2H085,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1578,PHI:1419,UniProt,I1S0X7,Broad,FGSG_10369,,,PH-1,GzC2H086,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1579,PHI:1420,UniProt,I1S172,Broad,FGSG_10470,,,PH-1,GzC2H088,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1580,PHI:1421,UniProt,I1S1A8,Broad,FGSG_10508,,,PH-1,GzC2H089,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1581,PHI:1422,UniProt,A0A0E0RXI2,EMBL,FGRAMPH1_01T08305,,,PH-1,GzC2H090,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1582,PHI:1423,UniProt,I1S2R1,Broad,FGSG_11061,,,PH-1,GzC2H091,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1583,PHI:1424,UniProt,I1S3J7,Broad,FGSG_11383,,,PH-1,GzC2H092,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1584,PHI:1425,UniProt,A0A098E2F3,EMBL,FGRAMPH1_01T22011,,,PH-1,GzC2H093,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1585,PHI:1426,UniProt,A0A1C3YHR0,EMBL,FGRAMPH1_01T01535,,,PH-1,GzC2H094,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1586,PHI:1427,UniProt,A0A1C3YHS2,EMBL,FGRAMPH1_01T01667,,,PH-1,GzC2H095,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1587,PHI:1428,UniProt,I1S5D9,Broad,FGSG_12057,,,PH-1,GzC2H096,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1588,PHI:1429,UniProt,A0A0E0SQI9,EMBL,FGRAMPH1_01T18733,,,PH-1,GzC2H097,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1589,PHI:1430,UniProt,A0A098E000,EMBL,FGRAMPH1_01T19023,,,PH-1,GzC2H098,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1590,PHI:1431,UniProt,A0A1C3YKN0,EMBL,FGRAMPH1_01T22981,,,PH-1,Pac1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1591,PHI:5693,UniProt,A0A1C3YKN0,EMBL,FGRAMPH1_01T22981,,,PH-1,Pac1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,MU,MU,,ISBN,no data found,"Fusarium genomics and molecular and cellular biology (Horizon Scientific Press, 2013, Chapter 15)",cbarreau@bordeaux.inra.fr,"reduced development under neutral and alkaline pH, and an earlier TRI gene inductin and toxin accumulation at acidic pH",,2013,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1592,PHI:1432,UniProt,A0A098DMZ8,EMBL,FGRAMPH1_01T23015,,,PH-1,GzC2H100,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1593,PHI:1433,UniProt,A0A098DP11,EMBL,FGRAMPH1_01T24563,,,PH-1,GzC2H102,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1594,PHI:1434,UniProt,I1S8Y5,Broad,FGSG_13314,,,PH-1,GzC2H103,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1595,PHI:1435,UniProt,A0A098DSB7,EMBL,FGRAMPH1_01T28185,,,PH-1,GzC2H104,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1596,PHI:1436,UniProt,A0A1C3YJ91,EMBL,FGRAMPH1_01T07427,,,PH-1,GzC2H105,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1597,PHI:1437,UniProt,A0A098DYE9,EMBL,FGRAMPH1_01T20733,,,PH-1,GzC2H106,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1598,PHI:1438,UniProt,I1SAT3,Broad,FGSG_13964,,,PH-1,GzC2H107,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1599,PHI:1439,UniProt,A0A098DCZ4,EMBL,FGRAMPH1_01T10051,,,PH-1,GzNot001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1600,PHI:1440,UniProt,I1SA65,Broad,FGSG_13746,,,PH-1,GzNot002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1601,PHI:1441,UniProt,I1RFP4,Broad,FGSG_02527,,,PH-1,GzDDT,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1602,PHI:1442,UniProt,I1RG27,Broad,FGSG_02676,,,PH-1,GzDNL,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1603,PHI:1443,UniProt,I1RB11,Broad,FGSG_00710,,,PH-1,GzGATA001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1604,PHI:1444,UniProt,I1RHM1,Broad,FGSG_03281,,,PH-1,GzGATA002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1605,PHI:1445,UniProt,A0A098DMI2,EMBL,FGRAMPH1_01T15741,,,PH-1,GzGATA003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1606,PHI:1446,UniProt,I1RUE0,Broad,FGSG_07830,,,PH-1,GzGATA004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1607,PHI:1447,UniProt,I1RUP1,Broad,FGSG_07941,,,PH-1,GzGATA005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1608,PHI:1448,UniProt,I1RWG5,Broad,FGSG_08634,,,PH-1,GzGATA006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1609,PHI:1449,UniProt,I1RYV4,Broad,FGSG_09565,,,PH-1,GzGATA007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1610,PHI:1450,UniProt,A0A0E0SN30,EMBL,FGRAMPH1_01T17027,,,PH-1,GzGATA008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1611,PHI:1451,UniProt,I1RQL1,Broad,FGSG_06356,,,PH-1,GzGH,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,increased,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1612,PHI:1452,UniProt,I1S282,Broad,FGSG_10868,,,PH-1,GzHSF003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1613,PHI:1453,UniProt,I1RA50,Broad,FGSG_00374,,,PH-1,GzAra001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1614,PHI:1454,UniProt,I1RCI0,Broad,FGSG_01295,,,PH-1,GzAra002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1615,PHI:1455,UniProt,I1RKU6,Broad,FGSG_04516,,,PH-1,GzAra003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1616,PHI:1456,UniProt,I1RN15,Broad,FGSG_05373,,,PH-1,GzAra004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1617,PHI:1457,UniProt,I1RRR9,Broad,FGSG_06805,,,PH-1,GzAra005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1618,PHI:1458,UniProt,Q4I7F9,Broad,FGSG_06849,,,PH-1,GzAra006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1619,PHI:1459,UniProt,I1RYE2,Broad,FGSG_09389,,,PH-1,GzAra007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1620,PHI:1460,UniProt,I1S2F6,Broad,FGSG_10948,,,PH-1,GzAra008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1621,PHI:1461,UniProt,I1RA31,Broad,FGSG_00352,,,PH-1,GzCCAAT001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1622,PHI:1462,UniProt,I1RC79,Broad,FGSG_01182,,,PH-1,GzCCAAT002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1623,PHI:1463,UniProt,I1RFW6,Broad,FGSG_02608,,,PH-1,GzCCAAT003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1624,PHI:1464,UniProt,I1RMV4,Broad,FGSG_05304,,,PH-1,GzCCAAT004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1625,PHI:1465,UniProt,I1RNC6,Broad,FGSG_05498,,,PH-1,GzCCAAT005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1626,PHI:1466,UniProt,I1RSG9,Broad,FGSG_07087,,,PH-1,GzCCAAT006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1627,PHI:1467,UniProt,I1RXZ0,Broad,FGSG_09217,,,PH-1,GzCCAAT007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1628,PHI:1468,UniProt,Q4HTT1,Broad,FGSG_11627,,,PH-1,GzCCAAT008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1629,PHI:1469,UniProt,I1R9Z0,Broad,FGSG_00307,,,PH-1,GzHMG001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1630,PHI:1470,UniProt,Q4IQX3,Broad,FGSG_00385,,,PH-1,GzHMG002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1631,PHI:1471,UniProt,I1RAY3,Broad,FGSG_00678,,,PH-1,GzHMG003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1632,PHI:1472,UniProt,I1RAZ9,Broad,FGSG_00696,,,PH-1,GzHMG004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1633,PHI:1473,UniProt,I1RB25,Broad,FGSG_00729,,,PH-1,GzHMG005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1634,PHI:1474,UniProt,I1RB89,Broad,FGSG_00799,,,PH-1,GzHMG006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1635,PHI:1475,UniProt,I1RBB7,Broad,FGSG_00829,,,PH-1,GzHMG007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1636,PHI:1476,UniProt,I1RC98,Broad,FGSG_01201,,,PH-1,GzHMG008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1637,PHI:1477,UniProt,I1RCK8,Broad,FGSG_01327,,,PH-1,GzHMG009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1638,PHI:1478,UniProt,I1RCP3,Broad,FGSG_01366,,,PH-1,GzHMG010,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1639,PHI:1479,UniProt,I1RD01,Broad,FGSG_01488,,,PH-1,GzHMG011,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1640,PHI:1480,UniProt,I1RD25,Broad,FGSG_01512,,,PH-1,GzHMG012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1641,PHI:1481,UniProt,I1RE60,Broad,FGSG_01934,,,PH-1,GzHMG013,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1642,PHI:1482,UniProt,I1RKH7,Broad,FGSG_04379,,,PH-1,GzHMG014,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1643,PHI:1483,UniProt,A0A1C3YN94,EMBL,FGRAMPH1_01T15577,,,PH-1,GzHMG015,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1644,PHI:1484,UniProt,I1RMG1,Broad,FGSG_05151,,,PH-1,GzHMG016,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1645,PHI:1485,UniProt,I1RMP0,Broad,FGSG_05233,,,PH-1,GzHMG017,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1646,PHI:1486,UniProt,I1RNM1,Broad,FGSG_05604,,,PH-1,GzHMG018,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1647,PHI:1487,UniProt,I1RQ92,Broad,FGSG_06231,,,PH-1,GzHMG019,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1648,PHI:1488,UniProt,I1RSA6,Broad,FGSG_07020,,,PH-1,GzHMG020,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1649,PHI:1489,UniProt,I1RSJ5,Broad,FGSG_07116,,,PH-1,GzHMG021,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1650,PHI:1490,UniProt,I1RSM1,Broad,FGSG_07144,,,PH-1,GzHMG022,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1651,PHI:1491,UniProt,I1RST1,Broad,FGSG_07214,,,PH-1,GzHMG023,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1652,PHI:1492,UniProt,Q4I5U9,Broad,FGSG_07409,,,PH-1,GzHMG024,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1653,PHI:1493,UniProt,I1RUP7,Broad,FGSG_07947,,,PH-1,GzHMG025,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1654,PHI:1494,UniProt,I1RX41,Broad,FGSG_08890,,,PH-1,MAT1-1-3,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1655,PHI:1495,UniProt,I1RX43,Broad,FGSG_08892,,,PH-1,MAT1-1-1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1656,PHI:1496,UniProt,I1RX44,Broad,FGSG_08893,,,PH-1,MAT1-2-1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1657,PHI:1497,UniProt,I1RZL9,Broad,FGSG_09868,,,PH-1,GzHMG029,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,wild type,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1658,PHI:1498,UniProt,I1S1Y4,Broad,FGSG_10762,,,PH-1,GzHMG030,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1659,PHI:1499,UniProt,A0A098D1L0,EMBL,FGRAMPH1_01T02089,,,PH-1,GzHMG031,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1660,PHI:1500,UniProt,I1S2F2,Broad,FGSG_10944,,,PH-1,GzHMG032,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1661,PHI:1501,UniProt,A0A098D1L0,EMBL,FGRAMPH1_01T02089,,,PH-1,GzHMG033,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1662,PHI:1502,UniProt,A0A0E0S657,EMBL,FGRAMPH1_01T14359,,,PH-1,GzHMG034,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1663,PHI:1503,UniProt,A0A0E0SES1,EMBL,FGRAMPH1_01T23389,,,PH-1,GzHMG035,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1664,PHI:1504,UniProt,A0A098DP54,EMBL,FGRAMPH1_01T24875,,,PH-1,GzHMG036,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1665,PHI:1505,UniProt,A0A098E396,EMBL,FGRAMPH1_01T20323,,,PH-1,GzHMG037,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1666,PHI:1506,UniProt,I1RC01,Broad,FGSG_01100,,,PH-1,GzHOME001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1667,PHI:1507,UniProt,I1RNA7,Broad,FGSG_05475,,,PH-1,GzHOME002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1668,PHI:1508,UniProt,A0A098DZQ8,EMBL,FGRAMPH1_01T18011,,,PH-1,GzHOME003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1669,PHI:1509,UniProt,A0A1C3YKQ0,EMBL,FGRAMPH1_01T23243,,,PH-1,GzHOME004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1670,PHI:1510,UniProt,A0A098DQ47,EMBL,FGRAMPH1_01T23953,,,PH-1,GzHOME005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1671,PHI:1511,UniProt,I1RXF3,Broad,FGSG_09019,,,PH-1,GzHOME009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,reduced,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1672,PHI:1512,UniProt,A0A098DPD9,EMBL,FGRAMPH1_01T28057,,,PH-1,GzHOME010,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1673,PHI:1513,UniProt,A0A1C3YLV1,EMBL,FGRAMPH1_01T28049,,,PH-1,GzHOME011,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1674,PHI:1514,UniProt,A0A0E0S972,EMBL,FGRAMPH1_01T26779,,,PH-1,GzHOME012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1675,PHI:1515,UniProt,I1RG67,Broad,FGSG_02718,,,PH-1,GzHOMEL009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1676,PHI:1516,UniProt,I1RMR8,Broad,FGSG_05264,,,PH-1,GzHOMEL012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1677,PHI:1517,UniProt,I1RPZ1,Broad,FGSG_06123,,,PH-1,GzHOMEL013,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1678,PHI:1518,UniProt,A0A098DTH7,EMBL,FGRAMPH1_01T23627,,,PH-1,GzHOMEL016,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1679,PHI:1519,UniProt,I1RSV8,Broad,FGSG_07243,,,PH-1,GzHOMEL018,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1680,PHI:1520,UniProt,A0A098DFE8,EMBL,FGRAMPH1_01T10739,,,PH-1,GzHOMEL024,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2010-05-04,MU,,,,,,,,,,,,,
,,Record 1681,PHI:1521,UniProt,I1RX98,Broad,FGSG_08954,,,PH-1,GzHOMEL025,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1682,PHI:1522,UniProt,I1RXA5,Broad,FGSG_08962,,,PH-1,GzHOMEL026,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1683,PHI:1523,UniProt,A0A0E0SGA3,EMBL,FGRAMPH1_01T27619,,,PH-1,GzHOMEL030,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1684,PHI:1524,UniProt,I1RZF2,Broad,FGSG_09791,,,PH-1,GzHOMEL033,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1685,PHI:1525,UniProt,Q4HY90,Broad,FGSG_10068,,,PH-1,GzHOMEL035,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1686,PHI:1526,UniProt,I1S0J3,Broad,FGSG_10221,,,PH-1,GzHOMEL036,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1687,PHI:1527,UniProt,I1S9A1,Broad,FGSG_13431,,,PH-1,GzHOMEL040,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1688,PHI:1528,UniProt,I1SAN0,Broad,FGSG_13911,,,PH-1,GzHOMEL041,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1689,PHI:1529,UniProt,I1RS41,Broad,FGSG_06948,,,PH-1,Gzscp,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1690,PHI:1530,UniProt,I1RWP4,Broad,FGSG_08722,,,PH-1,Gzsnd,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1691,PHI:1531,UniProt,Q4IPC8,Broad,FGSG_00930,,,PH-1,GzSsu72,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1692,PHI:1532,UniProt,I1RTF5,Broad,FGSG_07458,,,PH-1,GzLam001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1693,PHI:1533,UniProt,I1S0F5,Broad,FGSG_10179,,,PH-1,GzLam002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1694,PHI:1534,UniProt,I1RWM0,Broad,FGSG_08696,,,PH-1,GzMADS001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1695,PHI:1535,UniProt,I1RXD6,Broad,FGSG_09002,,,PH-1,GzMADS002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1696,PHI:1536,UniProt,I1RY98,Broad,FGSG_09339,,,PH-1,GzMADS003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1697,PHI:1537,UniProt,I1RA01,Broad,FGSG_00318,,,PH-1,MYT1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1698,PHI:1538,UniProt,I1RA07,Broad,FGSG_00324,,,PH-1,GzMyb002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1699,PHI:1539,UniProt,I1RCG0,Broad,FGSG_01274,,,PH-1,GzMyb003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1700,PHI:1540,UniProt,I1RCX3,Broad,FGSG_01457,,,PH-1,GzMyb004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1701,PHI:1541,UniProt,I1RE42,Broad,FGSG_01915,,,PH-1,GzFlbD,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,defective,defective,increased,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1702,PHI:1542,UniProt,I1RE51,Broad,FGSG_01925,,,PH-1,GzMyb006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1703,PHI:1543,UniProt,I1RFQ3,Broad,FGSG_02538,,,PH-1,GzMyb007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1704,PHI:1544,UniProt,A0A1C3YJ08,EMBL,FGRAMPH1_01T06521,,,PH-1,GzMyb008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1705,PHI:1545,UniProt,A0A1C3YJ08,EMBL,FGRAMPH1_01T06521,,,PH-1,GzMyb009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1706,PHI:1546,UniProt,Q4IB96,Broad,FGSG_05512,,,PH-1,GzMyb010,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1707,PHI:1547,UniProt,I1RRN6,Broad,FGSG_06768,,,PH-1,GzMyb011,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1708,PHI:1548,UniProt,I1RTE5,Broad,FGSG_07448,,,PH-1,GzMyb012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1709,PHI:1549,UniProt,I1RTN5,Broad,FGSG_07546,,,PH-1,MYT2,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,increased,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1710,PHI:1550,UniProt,I1RWN5,Broad,FGSG_08713,,,PH-1,GzMyb014,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1711,PHI:1551,UniProt,I1RZG7,Broad,FGSG_09807,,,PH-1,GzMyb015,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1712,PHI:1552,UniProt,I1S0N5,Broad,FGSG_10269,,,PH-1,GzMyb016,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1713,PHI:1553,UniProt,A0A0E0SQJ6,EMBL,FGRAMPH1_01T18469,,,PH-1,GzMyb017,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1714,PHI:1554,UniProt,I1RC64,Broad,FGSG_01167,,,PH-1,GzMyb018,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1715,PHI:1555,UniProt,I1RDG6,Broad,FGSG_01662,,,PH-1,GzMyb019,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1716,PHI:1556,UniProt,A0A0E0RVN3,EMBL,FGRAMPH1_01T07007,,,PH-1,GzNH001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1717,PHI:1557,UniProt,I1RBU9,Broad,FGSG_01040,,,PH-1,GzNH002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1718,PHI:1558,UniProt,A0A098E1X6,EMBL,FGRAMPH1_01T18275,,,PH-1,GzNH003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1719,PHI:1559,UniProt,I1RK21,Broad,FGSG_04209,,,PH-1,GzNEG001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1720,PHI:1560,UniProt,I1RTR8,Broad,FGSG_07583,,,PH-1,GzNEG002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1721,PHI:1561,UniProt,I1R9W2,Broad,FGSG_00276,,,PH-1,GzOB001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1722,PHI:1562,UniProt,I1RAH4,Broad,FGSG_00504,,,PH-1,GzOB002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1723,PHI:1563,UniProt,A0A1C3YHX8,EMBL,FGRAMPH1_01T01691,,,PH-1,GzOB003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1724,PHI:1564,UniProt,Q4IPZ1,Broad,FGSG_00717,,,PH-1,GzOB004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1725,PHI:1565,UniProt,I1RBF6,Broad,FGSG_00875,,,PH-1,GzOB005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1726,PHI:1566,UniProt,I1RC95,Broad,FGSG_01198,,,PH-1,GzOB006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1727,PHI:1567,UniProt,I1RCB7,Broad,FGSG_01220,,,PH-1,GzOB007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1728,PHI:1568,UniProt,I1RCE1,Broad,FGSG_01251,,,PH-1,GzOB008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1729,PHI:1569,UniProt,I1RCH5,Broad,FGSG_01290,,,PH-1,GzOB009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1730,PHI:1570,UniProt,I1RE46,Broad,FGSG_01920,,,PH-1,GzOB010,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1731,PHI:1571,UniProt,I1RE76,Broad,FGSG_01955,,,PH-1,GzOB011,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1732,PHI:1572,UniProt,A0A0E0RSG8,EMBL,FGRAMPH1_01T04773,,,PH-1,GzOB012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1733,PHI:1573,UniProt,I1RFJ2,Broad,FGSG_02470,,,PH-1,GzOB013,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1734,PHI:1574,UniProt,I1RFX8,Broad,FGSG_02622,,,PH-1,GzOB014,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1735,PHI:1575,UniProt,I1RIQ3,Broad,FGSG_03695,,,PH-1,GzOB015,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1736,PHI:1576,UniProt,I1RJY5,Broad,FGSG_04169,,,PH-1,GzOB016,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1737,PHI:1577,UniProt,I1RK79,Broad,FGSG_04273,,,PH-1,GzOB017,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1738,PHI:1578,UniProt,I1RKY2,Broad,FGSG_04554,,,PH-1,GzOB018,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1739,PHI:1579,UniProt,I1RM25,Broad,FGSG_05002,,,PH-1,GzOB019,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1740,PHI:1580,UniProt,I1RM35,Broad,FGSG_05012,,,PH-1,GzOB020,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1741,PHI:1581,UniProt,I1RPX8,Broad,FGSG_06110,,,PH-1,GzOB021,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1742,PHI:1582,UniProt,I1RQ81,Broad,FGSG_06220,,,PH-1,GzOB022,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1743,PHI:1583,UniProt,V6RLW4,Broad,FGSG_06777,,,PH-1,GzOB023,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1744,PHI:1584,UniProt,I1RS24,Broad,FGSG_06931,,,PH-1,GzOB024,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1745,PHI:1585,UniProt,I1RS43,Broad,FGSG_06951,,,PH-1,GzOB025,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1746,PHI:1586,UniProt,I1RSG4,Broad,FGSG_07082,,,PH-1,GzOB026,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1747,PHI:1587,UniProt,I1RSI4,Broad,FGSG_07105,,,PH-1,GzOB027,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1748,PHI:1588,UniProt,I1RSY2,Broad,FGSG_07269,,,PH-1,GzOB028,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1749,PHI:1589,UniProt,I1RWH5,Broad,FGSG_08645,,,PH-1,GzOB029,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1750,PHI:1590,UniProt,I1RWI5,Broad,FGSG_08655,,,PH-1,GzOB030,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1751,PHI:1591,UniProt,I1RWQ7,Broad,FGSG_08737,,,PH-1,GzOB031,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1752,PHI:1592,UniProt,I1RWS0,Broad,FGSG_08750,,,PH-1,GzOB032,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1753,PHI:1593,UniProt,I1RWS6,Broad,FGSG_08756,,,PH-1,GzOB033,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1754,PHI:1594,UniProt,V6RRH2,Broad,FGSG_08761,,,PH-1,GzOB034,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1755,PHI:1595,UniProt,I1RX22,Broad,FGSG_08865,,,PH-1,GzOB035,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1756,PHI:1596,UniProt,I1RXD4,Broad,FGSG_09000,,,PH-1,GzOB036,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1757,PHI:1597,UniProt,I1RYF6,Broad,FGSG_09406,,,PH-1,GzOB037,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1758,PHI:1598,UniProt,I1RZ35,Broad,FGSG_09654,,,PH-1,GzOB038,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1759,PHI:1599,UniProt,I1RZ39,Broad,FGSG_09662,,,PH-1,GzOB039,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1760,PHI:1600,UniProt,I1RZK5,Broad,FGSG_09852,,,PH-1,GzOB041,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1761,PHI:1601,UniProt,Q4HYQ4,Broad,FGSG_09904,,,PH-1,GzOB042,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1762,PHI:1602,UniProt,I1RZY1,Broad,FGSG_09991,,,PH-1,GzOB043,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1763,PHI:1603,UniProt,A0A0E0RW49,EMBL,FGRAMPH1_01T07339,,,PH-1,GzOB044,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1764,PHI:1604,UniProt,I1S1V9,Broad,FGSG_10733,,,PH-1,GzOB045,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1765,PHI:1605,UniProt,I1S216,Broad,FGSG_10797,,,PH-1,GzOB046,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1766,PHI:1606,UniProt,I1S8E2,Broad,FGSG_13120,,,PH-1,GzOB047,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1767,PHI:1607,UniProt,I1SAD7,Broad,FGSG_13818,,,PH-1,GzOB048,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1768,PHI:1608,UniProt,Q4IR08,Broad,FGSG_00350,,,PH-1,GzP53L001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1769,PHI:1609,UniProt,I1RJ69,Broad,FGSG_03874,,,PH-1,GzP53L002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1770,PHI:1610,UniProt,I1RSN1,Broad,FGSG_07157,,,PH-1,GzP53L003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1771,PHI:1611,UniProt,I1RVV2,Broad,FGSG_08397,,,PH-1,GzP53L004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1772,PHI:1612,UniProt,A0A0E0SEV4,EMBL,FGRAMPH1_01T26461,,,PH-1,GzP53L005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1773,PHI:1613,UniProt,I1S2J0,Broad,FGSG_10985,,,PH-1,GzP53L006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1774,PHI:1614,UniProt,I1RQD8,Broad,FGSG_06279,,,PH-1,GzSART1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1775,PHI:1615,UniProt,I1RZJ1,Broad,FGSG_09837,,,PH-1,GzSGT1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1776,PHI:1616,UniProt,I1RE55,Broad,FGSG_01929,,,PH-1,GzssDB001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1777,PHI:1617,UniProt,I1S0G0,Broad,FGSG_10186,,,PH-1,GzssDB002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1778,PHI:1618,UniProt,Q4IQT8,Broad,FGSG_00420,,,PH-1,GzFET5,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1779,PHI:1619,UniProt,I1RBK8,Broad,FGSG_00934,,,PH-1,GzJUM001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1780,PHI:1620,UniProt,I1RD69,Broad,FGSG_01558,,,PH-1,GzJUM002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1781,PHI:1621,UniProt,A0A098E3M9,EMBL,FGRAMPH1_01T18925,,,PH-1,GzRUM1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1782,PHI:1622,UniProt,I1RRU8,Broad,FGSG_06840,,,PH-1,GzJUM004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1783,PHI:1623,UniProt,I1S9T2,Broad,FGSG_13613,,,PH-1,GzJUM005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1784,PHI:1624,UniProt,A0A098E396,EMBL,FGRAMPH1_01T20323,,,PH-1,GzJUM006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1785,PHI:1625,UniProt,A0A1C3YLZ1,EMBL,FGRAMPH1_01T28207,,,PH-1,GzOpi,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,wild type,increased,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1786,PHI:1626,UniProt,V6QWX8,Broad,FGSG_00902,,,PH-1,GzTF2S001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1787,PHI:1627,UniProt,I1RW90,Broad,FGSG_08551,,,PH-1,GzTF2S002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1788,PHI:1628,UniProt,I1RDG9,Broad,FGSG_01665,,,PH-1,FgFSR1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1789,PHI:1629,UniProt,I1RAH2,Broad,FGSG_00502,,,PH-1,GzWing001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1790,PHI:1630,UniProt,I1RB71,Broad,FGSG_00778,,,PH-1,GzWing002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1791,PHI:1631,UniProt,I1RBL8,Broad,FGSG_00946,,,PH-1,GzWing003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1792,PHI:1632,UniProt,I1RBU0,Broad,FGSG_01030,,,PH-1,GzWing004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1793,PHI:1633,UniProt,I1RC15,Broad,FGSG_01116,,,PH-1,GzWing005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1794,PHI:1634,UniProt,I1RDI9,Broad,FGSG_01689,,,PH-1,GzWing006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1795,PHI:1635,UniProt,I1RFX1,Broad,FGSG_02615,,,PH-1,GzWing007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1796,PHI:1636,UniProt,I1RIG5,Broad,FGSG_03597,,,PH-1,FgFlbB,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1797,PHI:1637,UniProt,Q4IEV4,Broad,FGSG_04254,,,PH-1,GzWing009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1798,PHI:1638,UniProt,I1RN27,Broad,FGSG_05388,,,PH-1,GzWing010,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1799,PHI:1639,UniProt,V6RAN7,Broad,FGSG_05520,,,PH-1,GzWing011,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1800,PHI:1640,UniProt,I1RPI0,Broad,FGSG_05949,,,PH-1,GzWing012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1801,PHI:1641,UniProt,A0A0E0SIF3,EMBL,FGRAMPH1_01T19813,,,PH-1,FgFlbA,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1802,PHI:1642,UniProt,I1RQL4,Broad,FGSG_06359,,,PH-1,GzWing014,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1803,PHI:1643,UniProt,I1RS37,Broad,FGSG_06944,,,PH-1,GzWing015,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1804,PHI:1644,UniProt,I1RTB9,Broad,FGSG_07420,,,PH-1,GzRFX1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1805,PHI:1645,UniProt,I1RTD1,Broad,FGSG_07433,,,PH-1,GzWing017,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1806,PHI:1646,UniProt,I1RW28,Broad,FGSG_08481,,,PH-1,GzWing018,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1807,PHI:1647,UniProt,I1RWA9,Broad,FGSG_08572,,,PH-1,GzWing019,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1808,PHI:1648,UniProt,A0A098DDX5,EMBL,FGRAMPH1_01T10651,,,PH-1,GzWing020,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1809,PHI:1649,UniProt,I1RZ94,Broad,FGSG_09724,,,PH-1,GzWing021,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1810,PHI:1650,UniProt,A0A098DDX5,EMBL,FGRAMPH1_01T10651,,,PH-1,GzWing022,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1811,PHI:1651,UniProt,I1S0U2,Broad,FGSG_10331,,,PH-1,GzWing023,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1812,PHI:1652,UniProt,I1S219,Broad,FGSG_10800,,,PH-1,GzWing024,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1813,PHI:1653,UniProt,A0A0E0SLE9,EMBL,FGRAMPH1_01T20715,,,PH-1,GzWing026,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1814,PHI:1654,UniProt,A0A098D1G8,EMBL,FGRAMPH1_01T01995,,,PH-1,GzWing027,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1815,PHI:1655,UniProt,I1S9V9,Broad,FGSG_13640,,,PH-1,GzWing028,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1816,PHI:1656,UniProt,I1RFN9,Broad,FGSG_02520,,,PH-1,GzYL,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1817,PHI:1657,UniProt,I1RF25,Broad,FGSG_02288,,,PH-1,GzCCCH001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1818,PHI:1658,UniProt,I1RRW3,Broad,FGSG_06860,,,PH-1,GzCCCH002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1819,PHI:1659,UniProt,A0A0E0SMM8,EMBL,FGRAMPH1_01T20573,,,PH-1,GzCCCH003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1820,PHI:1660,UniProt,A0A098D0V3,EMBL,FGRAMPH1_01T00469,,,PH-1,GzCCCH004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1821,PHI:1661,UniProt,I1REA2,Broad,FGSG_01984,,,PH-1,GzCCHC001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1822,PHI:1662,UniProt,A0A0E0RST9,EMBL,FGRAMPH1_01T05015,,,PH-1,GzCCHC002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1823,PHI:1663,UniProt,I1RFZ8,Broad,FGSG_02646,,,PH-1,GzCCHC003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1824,PHI:1664,UniProt,I1RMT3,Broad,FGSG_05280,,,PH-1,GzCCHC004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1825,PHI:1665,UniProt,I1RS06,Broad,FGSG_06910,,,PH-1,GzCCHC005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1826,PHI:1666,UniProt,I1RX47,Broad,FGSG_08897,,,PH-1,GzCCHC006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1827,PHI:1667,UniProt,I1RZP2,Broad,FGSG_09892,,,PH-1,GzCCHC007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1828,PHI:1668,UniProt,I1S0C1,Broad,FGSG_10143,,,PH-1,GzCCHC008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1829,PHI:1669,UniProt,A0A1C3YJB7,EMBL,FgramPH1_01t07709,,,PH-1,GzCCHC009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1830,PHI:1670,UniProt,I1S0Q0,Broad,FGSG_10286,,,PH-1,GzCCHC010,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1831,PHI:1671,UniProt,Q4HWE2,Broad,FGSG_10716,,,PH-1,GzCCHC011,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,defective,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1832,PHI:1672,UniProt,I1S802,Broad,FGSG_12977,,,PH-1,GzCCHC012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1833,PHI:1673,UniProt,Q4IMZ7,Broad,FGSG_01411,,,PH-1,GzDHHC001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1834,PHI:1674,UniProt,Q4IA62,Broad,FGSG_05896,,,PH-1,GzDHHC002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1835,PHI:1675,UniProt,Q4I8B6,Broad,FGSG_06542,,,PH-1,GzDHHC003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1836,PHI:1676,UniProt,Q4I2M7,Broad,FGSG_08531,,,PH-1,GzDHHC004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1837,PHI:1677,UniProt,Q4I1J3,Broad,FGSG_08915,,,PH-1,GzDHHC005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1838,PHI:1678,UniProt,A0A0E0SQV5,EMBL,FGRAMPH1_01T17123,,,PH-1,GzGRF,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1839,PHI:1679,UniProt,I1RW03,Broad,FGSG_08455,,,PH-1,GzMIZ001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1840,PHI:1680,UniProt,I1S004,Broad,FGSG_10015,,,PH-1,GzMIZ002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1841,PHI:1681,UniProt,I1REN7,Broad,FGSG_02130,,,PH-1,GzNF001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1842,PHI:1682,UniProt,I1RSF8,Broad,FGSG_07076,,,PH-1,GzNF002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1843,PHI:1683,UniProt,I1RK33,Broad,FGSG_04221,,,PH-1,GzRad001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1844,PHI:1684,UniProt,A0A1C3YN69,EMBL,FGRAMPH1_01T14857,,,PH-1,GzRad002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1845,PHI:1685,UniProt,I1S5Z3,Broad,FGSG_12264,,,PH-1,GzRad003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1846,PHI:1686,UniProt,A0A098D4S1,EMBL,FGRAMPH1_01T04263,,,PH-1,GzZC001,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1847,PHI:1687,UniProt,A0A1C3YIX9,EMBL,FGRAMPH1_01T04215,,,PH-1,GzZC002,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1848,PHI:1688,UniProt,I1RWZ1,Broad,FGSG_08831,,,PH-1,GzZC003,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1849,PHI:1689,UniProt,A0A0E0RVT6,EMBL,FGRAMPH1_01T07113,,,PH-1,GzZC004,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1850,PHI:1690,UniProt,A0A0E0SG97,EMBL,FGRAMPH1_01T27309,,,PH-1,GzZC005,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1851,PHI:1691,UniProt,A0A0E0RVH6,EMBL,FGRAMPH1_01T06893,,,PH-1,GzZC006,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1852,PHI:1692,UniProt,I1RYR6,Broad,FGSG_09524,,,PH-1,GzZC007,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1853,PHI:1693,UniProt,A0A1C3YM10,EMBL,FGRAMPH1_01T27295,,,PH-1,GzZC008,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1854,PHI:1694,UniProt,A0A0E0S8J5,EMBL,FGRAMPH1_01T16041,,,PH-1,GzZC009,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1855,PHI:1695,UniProt,A0A1C3YKM5,EMBL,FGRAMPH1_01T20929,,,PH-1,GzZC010,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1856,PHI:1696,UniProt,A0A098E0R6,EMBL,FGRAMPH1_01T21115,,,PH-1,GzZC011,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1857,PHI:1697,UniProt,A0A098E4D6,EMBL,FGRAMPH1_01T22123,,,PH-1,GzZC012,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1858,PHI:1698,UniProt,A0A1C3YKQ6,EMBL,FGRAMPH1_01T20737,,,PH-1,GzZC013,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1859,PHI:1699,UniProt,A0A1C3YNC0,EMBL,FGRAMPH1_01T15871,,,PH-1,GzZC014,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1860,PHI:1700,UniProt,I1RL82,Broad,FGSG_04666,,,PH-1,GzZC015,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1861,PHI:1701,UniProt,A0A1C3YN88,EMBL,FGRAMPH1_01T15443,,,PH-1,GzZC016,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1862,PHI:1702,UniProt,A0A098DS14,EMBL,FGRAMPH1_01T25129,,,PH-1,GzZC017,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1863,PHI:1703,UniProt,I1RTQ4,Broad,FGSG_07568,,,PH-1,GzZC018,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1864,PHI:1704,UniProt,I1RPF7,Broad,FGSG_05926,,,PH-1,GzZC019,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1865,PHI:1705,UniProt,A0A098DK43,EMBL,FGRAMPH1_01T14045,,,PH-1,GzZC020,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1866,PHI:1706,UniProt,A0A1C3YN52,EMBL,FGRAMPH1_01T13925,,,PH-1,GzZC021,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1867,PHI:1707,UniProt,A0A098DJJ8,EMBL,FGRAMPH1_01T14653,,,PH-1,GzZC022,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1868,PHI:1708,UniProt,I1RP73,Broad,FGSG_05827,,,PH-1,GzZC023,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1869,PHI:1709,UniProt,I1RR13,Broad,FGSG_06516,,,PH-1,GzZC024,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1870,PHI:1710,UniProt,A0A1C3YMV1,EMBL,FGRAMPH1_01T13273,,,PH-1,GzZC025,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1871,PHI:1711,UniProt,A0A098D619,EMBL,FGRAMPH1_01T05177,,,PH-1,GzZC026,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1872,PHI:1712,UniProt,I1RMV9,Broad,FGSG_05309,,,PH-1,GzZC027,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1873,PHI:1713,UniProt,A0A1C3YMG6,EMBL,FGRAMPH1_01T11399,,,PH-1,GzZC028,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1874,PHI:1714,UniProt,A0A1C3YKY1,EMBL,FGRAMPH1_01T22301,,,PH-1,GzZC029,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1875,PHI:1715,UniProt,A0A098DYW2,EMBL,FGRAMPH1_01T20169,,,PH-1,GzZC030,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1876,PHI:1716,UniProt,I1RLI0,Broad,FGSG_04782,,,PH-1,GzZC031,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1877,PHI:1717,UniProt,A0A1C3YHD5,EMBL,FGRAMPH1_01T00415,,,PH-1,GzZC032,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1878,PHI:1718,UniProt,A0A1C3YLS9,EMBL,FGRAMPH1_01T26197,,,PH-1,GzZC033,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1879,PHI:1719,UniProt,I1S9U4,Broad,FGSG_13625,,,PH-1,GzZC034,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1880,PHI:1720,UniProt,I1S956,Broad,FGSG_13386,,,PH-1,GzZC035,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1881,PHI:1721,UniProt,A0A098DD67,EMBL,FGRAMPH1_01T10209,,,PH-1,GzZC036,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1882,PHI:1722,UniProt,I1S8C0,Broad,FGSG_13098,,,PH-1,GzZC037,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1883,PHI:1723,UniProt,I1S832,Broad,FGSG_13008,,,PH-1,GzZC038,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1884,PHI:1724,UniProt,I1SAE9,Broad,FGSG_13830,,,PH-1,GzZC039,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1885,PHI:1725,UniProt,A0A098E321,EMBL,FGRAMPH1_01T21521,,,PH-1,GzZC040,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1886,PHI:1726,UniProt,I1S9C7,Broad,FGSG_13457,,,PH-1,GzZC041,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1887,PHI:1727,UniProt,A0A098D935,EMBL,FGRAMPH1_01T06321,,,PH-1,GzZC042,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1888,PHI:1728,UniProt,I1S5L3,Broad,FGSG_12134,,,PH-1,GzZC043,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1889,PHI:1729,UniProt,I1S5H3,Broad,FGSG_12094,,,PH-1,GzZC044,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1890,PHI:1730,UniProt,I1S6C7,Broad,FGSG_12398,,,PH-1,GzZC045,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1891,PHI:1731,UniProt,A0A0E0RRM0,EMBL,FGRAMPH1_01T04175,,,PH-1,GzZC046,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1892,PHI:1732,UniProt,I1S6B4,Broad,FGSG_12385,,,PH-1,GzZC047,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1893,PHI:1733,UniProt,A0A098DWX2,EMBL,FGRAMPH1_01T16789,,,PH-1,GzZC048,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1894,PHI:1734,UniProt,I1S6Y8,Broad,FGSG_12611,,,PH-1,GzZC049,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1895,PHI:1735,UniProt,I1S6X4,Broad,FGSG_12597,,,PH-1,GzZC050,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1896,PHI:1736,UniProt,I1S4F3,Broad,FGSG_11720,,,PH-1,GzZC051,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1897,PHI:1737,UniProt,I1S4E2,Broad,FGSG_11709,,,PH-1,GzZC052,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1898,PHI:1738,UniProt,I1S4B9,Broad,FGSG_11686,,,PH-1,GzZC053,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1899,PHI:1739,UniProt,I1S7B9,Broad,FGSG_12742,,,PH-1,GzZC054,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1900,PHI:1740,UniProt,A0A1C3YJK4,EMBL,FGRAMPH1_01T17629,,,PH-1,GzZC055,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1901,PHI:1741,UniProt,I1S780,Broad,FGSG_12703,,,PH-1,GzZC056,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1902,PHI:1742,UniProt,I1S7H5,Broad,FGSG_12798,,,PH-1,GzZC057,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1903,PHI:1743,UniProt,I1S8J4,Broad,FGSG_13172,,,PH-1,GzZC058,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1904,PHI:1744,UniProt,I1RX18,Broad,FGSG_08861,,,PH-1,GzZC059,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1905,PHI:1745,UniProt,I1RWX2,Broad,FGSG_08808,,,PH-1,GzZC060,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1906,PHI:1746,UniProt,I1RWV5,Broad,FGSG_08791,,,PH-1,GzZC061,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1907,PHI:1747,UniProt,I1S6W1,Broad,FGSG_12584,,,PH-1,GzZC062,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1908,PHI:1748,UniProt,A0A098DIG5,EMBL,FGRAMPH1_01T11907,,,PH-1,GzZC063,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1909,PHI:1749,UniProt,I1S4A5,Broad,FGSG_11672,,,PH-1,GzZC064,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1910,PHI:1750,UniProt,I1S487,Broad,FGSG_11654,,,PH-1,GzZC065,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1911,PHI:1751,UniProt,I1RZ96,Broad,FGSG_09726,,,PH-1,GzZC066,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1912,PHI:1752,UniProt,I1RZR8,Broad,FGSG_09921,,,PH-1,GzZC067,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1913,PHI:1753,UniProt,I1RZN4,Broad,FGSG_09884,,,PH-1,GzZC068,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1914,PHI:1754,UniProt,A0A1C3YJ77,EMBL,FGRAMPH1_01T08353,,,PH-1,GzZC069,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1915,PHI:1755,UniProt,A0A098DDB6,EMBL,FGRAMPH1_01T08275,,,PH-1,GzZC070,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1916,PHI:1756,UniProt,A0A098D2S6,EMBL,FGRAMPH1_01T01903,,,PH-1,GzZC071,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1917,PHI:1757,UniProt,I1RYY1,Broad,FGSG_09594,,,PH-1,GzZC072,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1918,PHI:1758,UniProt,I1RXV2,Broad,FGSG_09178,,,PH-1,GzZC073,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1919,PHI:1759,UniProt,I1RXS2,Broad,FGSG_09147,,,PH-1,GzZC074,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1920,PHI:1760,UniProt,I1RXP9,Broad,FGSG_09123,,,PH-1,GzZC075,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1921,PHI:1761,UniProt,I1RXN7,Broad,FGSG_09111,,,PH-1,GzZC076,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1922,PHI:1762,UniProt,I1RXJ4,Broad,FGSG_09065,,,PH-1,GzZC077,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1923,PHI:1763,UniProt,I1RXE8,Broad,FGSG_09014,,,PH-1,GzZC078,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1924,PHI:1764,UniProt,Q4I0C5,Broad,FGSG_09333,,,PH-1,GzZC079,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1925,PHI:1765,UniProt,I1RY91,Broad,FGSG_09331,,,PH-1,GzZC080,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1926,PHI:1766,UniProt,I1S160,Broad,FGSG_10458,,,PH-1,GzZC081,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1927,PHI:1767,UniProt,A0A1C3YJD8,EMBL,FGRAMPH1_01T08087,,,PH-1,GzZC082,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1928,PHI:1768,UniProt,I1RAN6,Broad,FGSG_00568,,,PH-1,GzZC083,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1929,PHI:1769,UniProt,I1RXB2,Broad,FGSG_08972,,,PH-1,GzZC084,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1930,PHI:1770,UniProt,I1RX79,Broad,FGSG_08930,,,PH-1,GzZC085,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1931,PHI:1771,UniProt,I1RX74,Broad,FGSG_08924,,,PH-1,GzZC086,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,wild type,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1932,PHI:1772,UniProt,I1S053,Broad,FGSG_10069,,,PH-1,GzZC087,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1933,PHI:1773,UniProt,I1S409,Broad,FGSG_11561,,,PH-1,GzZC088,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1934,PHI:1774,UniProt,A0A098DLE7,EMBL,FGRAMPH1_01T15969,,,PH-1,GzZC089,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1935,PHI:1775,UniProt,I1S5X3,Broad,FGSG_12244,,,PH-1,GzZC090,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1936,PHI:1776,UniProt,A0A098DBD1,EMBL,FGRAMPH1_01T07923,,,PH-1,GzZC091,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1937,PHI:1777,UniProt,I1S2U0,Broad,FGSG_11093,,,PH-1,GzZC092,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1938,PHI:1778,UniProt,I1S353,Broad,FGSG_11218,,,PH-1,GzZC093,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1939,PHI:1779,UniProt,I1S325,Broad,FGSG_11186,,,PH-1,GzZC094,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1940,PHI:1780,UniProt,A0A1C3YKG5,EMBL,FGRAMPH1_01T21659,,,PH-1,GzZC095,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1941,PHI:1781,UniProt,I1S389,Broad,FGSG_11262,,,PH-1,GzZC096,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1942,PHI:1782,UniProt,A0A098DZF1,EMBL,FGRAMPH1_01T21861,,,PH-1,GzZC097,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1943,PHI:1783,UniProt,I1S2C5,Broad,FGSG_10914,,,PH-1,GzZC098,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1944,PHI:1784,UniProt,I1S2A9,Broad,FGSG_10895,,,PH-1,GzZC099,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1945,PHI:1785,UniProt,A0A098E219,EMBL,FGRAMPH1_01T20531,,,PH-1,GzZC100,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1946,PHI:1786,UniProt,A0A098DB09,EMBL,FGRAMPH1_01T08673,,,PH-1,GzZC101,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1947,PHI:1787,UniProt,I1S1P9,Broad,FGSG_10660,,,PH-1,GzZC102,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1948,PHI:1788,UniProt,I1S1N1,Broad,FGSG_10639,,,PH-1,GzZC103,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1949,PHI:1789,UniProt,I1RVU7,Broad,FGSG_08392,,,PH-1,GzZC104,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1950,PHI:1790,UniProt,I1RVT7,Broad,FGSG_08380,,,PH-1,GzZC105,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1951,PHI:1791,UniProt,I1RVN8,Broad,FGSG_08321,,,PH-1,GzZC106,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1952,PHI:1792,UniProt,A0A098DE24,EMBL,FGRAMPH1_01T09789,,,PH-1,GzZC107,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1953,PHI:1793,UniProt,I1RWT7,Broad,FGSG_08769,,,PH-1,GzZC108,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1954,PHI:1794,UniProt,V6RJG0,Broad,FGSG_08626,,,PH-1,GzZC109,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1955,PHI:1795,UniProt,I1RSX8,Broad,FGSG_07265,,,PH-1,GzZC110,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1956,PHI:1796,UniProt,I1RSR7,Broad,FGSG_07198,,,PH-1,GzZC111,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1957,PHI:1797,UniProt,I1RSR1,Broad,FGSG_07192,,,PH-1,GzZC112,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1958,PHI:1798,UniProt,A0A098DBH9,EMBL,FGRAMPH1_01T08951,,,PH-1,GzZC113,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1959,PHI:1799,UniProt,I1RBN6,Broad,FGSG_00967,,,PH-1,GzZC114,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1960,PHI:1800,UniProt,I1RE61,Broad,FGSG_01936,,,PH-1,GzZC115,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1961,PHI:1801,UniProt,I1RVB5,Broad,FGSG_08182,,,PH-1,GzZC116,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1962,PHI:1802,UniProt,I1RVB2,Broad,FGSG_08179,,,PH-1,GzZC117,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1963,PHI:1803,UniProt,I1RUX9,Broad,FGSG_08038,,,PH-1,GzZC118,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1964,PHI:1804,UniProt,I1RUX5,Broad,FGSG_08034,,,PH-1,GzZC119,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1965,PHI:1805,UniProt,A0A0E0SG99,EMBL,FGRAMPH1_01T24157,,,PH-1,GzZC120,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1966,PHI:1806,UniProt,A0A1C3YLR5,EMBL,FGRAMPH1_01T26001,,,PH-1,GzZC121,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1967,PHI:1807,UniProt,I1RUM5,Broad,FGSG_07924,,,PH-1,GzZC122,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1968,PHI:1808,UniProt,A0A1C3YIU5,EMBL,FGRAMPH1_01T05497,,,PH-1,GzZC123,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1969,PHI:1809,UniProt,I1REW1,Broad,FGSG_02215,,,PH-1,GzZC124,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1970,PHI:1810,UniProt,I1RUJ0,Broad,FGSG_07884,,,PH-1,GzZC125,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1971,PHI:1811,UniProt,A0A098DUX9,EMBL,FGRAMPH1_01T25765,,,PH-1,GzZC126,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1972,PHI:1812,UniProt,I1RV71,Broad,FGSG_08135,,,PH-1,GzZC127,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1973,PHI:1813,UniProt,I1RV20,Broad,FGSG_08080,,,PH-1,GzZC128,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1974,PHI:1814,UniProt,I1RV04,Broad,FGSG_08064,,,PH-1,GzZC129,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1975,PHI:1815,UniProt,I1RL60,Broad,FGSG_04643,,,PH-1,GzZC130,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1976,PHI:1816,UniProt,I1RRS3,Broad,FGSG_06810,,,PH-1,GzZC131,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1977,PHI:1817,UniProt,I1RL07,Broad,FGSG_04581,,,PH-1,ZEAR,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1978,PHI:1818,UniProt,A0A1C3YKI7,EMBL,FGRAMPH1_01T22387,,,PH-1,GzZC133,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1979,PHI:1819,UniProt,A0A098E4H8,EMBL,FGRAMPH1_01T18761,,,PH-1,GzZC134,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1980,PHI:1820,UniProt,A0A1C3YL31,EMBL,FGRAMPH1_01T24603,,,PH-1,GzZC135,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1981,PHI:1821,UniProt,A0A1C3YMB1,EMBL,FGRAMPH1_01T10933,,,PH-1,GzZC136,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1982,PHI:1822,UniProt,I1S1D3,Broad,FGSG_10533,,,PH-1,GzZC137,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1983,PHI:1823,UniProt,A0A1C3YLU9,EMBL,FGRAMPH1_01T27983,,,PH-1,GzZC138,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1984,PHI:1824,UniProt,A0A1C3YLM9,EMBL,FGRAMPH1_01T27247,,,PH-1,GzZC139,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1985,PHI:1825,UniProt,I1RY88,Broad,FGSG_09328,,,PH-1,GzZC140,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1986,PHI:1826,UniProt,A0A1C3YKC2,EMBL,FGRAMPH1_01T20933,,,PH-1,GzZC141,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1987,PHI:1827,UniProt,I1S2W8,Broad,FGSG_11124,,,PH-1,GzZC142,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1988,PHI:1828,UniProt,A0A1C3YKF7,EMBL,FGRAMPH1_01T21503,,,PH-1,GzZC143,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1989,PHI:1829,UniProt,A0A098DCA9,EMBL,FGRAMPH1_01T08565,,,PH-1,GzZC144,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1990,PHI:1830,UniProt,A0A0E0S9J4,EMBL,FGRAMPH1_01T25909,,,PH-1,GzZC145,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1991,PHI:1831,UniProt,A0A0E0S3R6,EMBL,FGRAMPH1_01T12677,,,PH-1,GzZC146,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1992,PHI:1832,UniProt,A0A1C3YMK9,EMBL,FGRAMPH1_01T11977,,,PH-1,GzZC147,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1993,PHI:1833,UniProt,A0A1C3YNA1,EMBL,FGRAMPH1_01T14721,,,PH-1,GzZC148,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1994,PHI:1834,UniProt,A0A098E2K8,EMBL,FGRAMPH1_01T18727,,,PH-1,GzZC149,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1995,PHI:1835,UniProt,I1RIL1,Broad,FGSG_03649,,,PH-1,GzZC150,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1996,PHI:1836,UniProt,A0A0E0RU12,EMBL,FGRAMPH1_01T05865,,,PH-1,GzZC151,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1997,PHI:1837,UniProt,A0A0E0RTZ8,EMBL,FGRAMPH1_01T05837,,,PH-1,GzZC152,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1998,PHI:1838,UniProt,I1RGC8,Broad,FGSG_02787,,,PH-1,GzZC153,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 1999,PHI:1839,UniProt,I1RDM2,Broad,FGSG_01731,,,PH-1,GzZC154,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2000,PHI:1840,UniProt,A0A098DUU9,EMBL,FGRAMPH1_01T22329,,,PH-1,GzZC155,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2001,PHI:1841,UniProt,A0A098DL22,EMBL,FGRAMPH1_01T13697,,,PH-1,GzZC156,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2002,PHI:1842,UniProt,I1RBA2,Broad,FGSG_00813,,,PH-1,GzZC157,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2003,PHI:1843,UniProt,I1S4X3,Broad,FGSG_11891,,,PH-1,GzZC158,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2004,PHI:1844,UniProt,I1S708,Broad,FGSG_12631,,,PH-1,GzZC159,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2005,PHI:1845,UniProt,I1S4B6,Broad,FGSG_11683,,,PH-1,GzZC160,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2006,PHI:1846,UniProt,A0A098DVU1,EMBL,FGRAMPH1_01T17809,,,PH-1,GzZC161,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2007,PHI:1847,UniProt,I1RYK8,Broad,FGSG_09464,,,PH-1,GzZC162,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2008,PHI:1848,UniProt,I1RXV1,Broad,FGSG_09177,,,PH-1,GzZC163,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2009,PHI:1849,UniProt,A0A0E0RWM1,EMBL,FGRAMPH1_01T07685,,,PH-1,GzZC164,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2010,PHI:1850,UniProt,I1RXK9,Broad,FGSG_09080,,,PH-1,GzZC165,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2011,PHI:1851,UniProt,A0A1C3YLW2,EMBL,FGRAMPH1_01T28009,,,PH-1,GzZC166,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2012,PHI:1852,UniProt,A0A0E0RXB5,EMBL,FGRAMPH1_01T08173,,,PH-1,GzZC167,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2013,PHI:1853,UniProt,A0A0E0SH47,EMBL,FGRAMPH1_01T27625,,,PH-1,GzZC168,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2014,PHI:1854,UniProt,A0A1C3YJ24,EMBL,FGRAMPH1_01T07213,,,PH-1,GzZC169,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2015,PHI:1855,UniProt,I1S611,Broad,FGSG_12282,,,PH-1,GzZC170,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2016,PHI:1856,UniProt,A0A098E5B5,EMBL,FGRAMPH1_01T21599,,,PH-1,GzZC171,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2017,PHI:1857,UniProt,I1S3I1,Broad,FGSG_11364,,,PH-1,GzZC172,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2018,PHI:1858,UniProt,I1S3H6,Broad,FGSG_11358,,,PH-1,GzZC173,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2019,PHI:1859,UniProt,I1S3H3,Broad,FGSG_11355,,,PH-1,GzZC174,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2020,PHI:1860,UniProt,I1RVR1,Broad,FGSG_08349,,,PH-1,GzZC175,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2021,PHI:1861,UniProt,A0A098DBF3,EMBL,FGRAMPH1_01T08901,,,PH-1,GzZC176,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2022,PHI:1862,UniProt,I1RL97,Broad,FGSG_04683,,,PH-1,GzZC177,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2023,PHI:1863,UniProt,A0A1C3YNB4,EMBL,FGRAMPH1_01T15849,,,PH-1,GzZC178,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2024,PHI:1864,UniProt,A0A098E1A2,EMBL,FGRAMPH1_01T21603,,,PH-1,GzZC179,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2025,PHI:1865,UniProt,A0A1C3YM01,EMBL,FGRAMPH1_01T08925,,,PH-1,GzZC180,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2026,PHI:1866,UniProt,A0A1C3YJ54,EMBL,FGRAMPH1_01T05505,,,PH-1,GzZC181,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2027,PHI:1867,UniProt,A0A098DKZ1,EMBL,FGRAMPH1_01T15619,,,PH-1,GzZC182,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2028,PHI:1868,UniProt,I1RKR4,Broad,FGSG_04480,,,PH-1,GzZC183,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2029,PHI:1869,UniProt,A0A0E0RS25,EMBL,FGRAMPH1_01T04487,,,PH-1,GzZC184,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2030,PHI:1870,UniProt,I1RDS9,Broad,FGSG_01795,,,PH-1,GzZC185,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2031,PHI:1871,UniProt,A0A098DPU7,EMBL,FGRAMPH1_01T25269,,,PH-1,GzZC186,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2032,PHI:1872,UniProt,A0A1C3YL60,EMBL,FGRAMPH1_01T25209,,,PH-1,GzZC187,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2033,PHI:1873,UniProt,I1RTT8,Broad,FGSG_07604,,,PH-1,GzZC188,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2034,PHI:1874,UniProt,A0A0E0S9S1,EMBL,FGRAMPH1_01T25165,,,PH-1,GzZC189,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2035,PHI:1875,UniProt,A0A098DRD7,EMBL,FGRAMPH1_01T25161,,,PH-1,GzZC190,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2036,PHI:1876,UniProt,I1RD28,Broad,FGSG_01515,,,PH-1,GzZC191,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2037,PHI:1877,UniProt,I1RPI7,Broad,FGSG_05958,,,PH-1,GzZC192,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2038,PHI:1878,UniProt,I1RPF6,Broad,FGSG_05925,,,PH-1,GzZC193,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2039,PHI:1879,UniProt,I1RJB8,Broad,FGSG_03929,,,PH-1,GzZC194,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2040,PHI:1880,UniProt,I1RJB0,Broad,FGSG_03919,,,PH-1,GzZC195,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2041,PHI:1881,UniProt,I1RJA3,Broad,FGSG_03912,,,PH-1,GzZC196,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2042,PHI:1882,UniProt,I1RJ84,Broad,FGSG_03892,,,PH-1,GzZC197,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2043,PHI:1883,UniProt,I1RJ71,Broad,FGSG_03878,,,PH-1,GzZC198,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2044,PHI:1884,UniProt,I1RJ58,Broad,FGSG_03861,,,PH-1,GzZC199,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2045,PHI:1885,UniProt,I1RJ54,Broad,FGSG_03857,,,PH-1,GzZC200,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2046,PHI:1886,UniProt,A0A0E0SB30,EMBL,FGRAMPH1_01T25399,,,PH-1,GzZC201,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2047,PHI:1887,UniProt,A0A1C3YMS9,EMBL,FGRAMPH1_01T12829,,,PH-1,GzZC202,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2048,PHI:1888,UniProt,A0A0E0S3X1,EMBL,FGRAMPH1_01T12787,,,PH-1,GzZC203,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2049,PHI:1889,UniProt,I1RHX4,Broad,FGSG_03390,,,PH-1,GzZC204,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2050,PHI:1890,UniProt,I1RTH7,Broad,FGSG_07482,,,PH-1,GzZC205,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2051,PHI:1891,UniProt,A0A0E0SEC8,EMBL,FGRAMPH1_01T23081,,,PH-1,GzZC206,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2052,PHI:1892,UniProt,I1RRH8,Broad,FGSG_06699,,,PH-1,GzZC207,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2053,PHI:1893,UniProt,I1RNY0,Broad,FGSG_05725,,,PH-1,GzZC208,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2054,PHI:1894,UniProt,A0A1C3YJU8,EMBL,FGRAMPH1_01T18585,,,PH-1,GzZC209,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2055,PHI:1895,UniProt,I1RNU2,Broad,FGSG_05682,,,PH-1,GzZC210,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2056,PHI:1896,UniProt,I1RNR1,Broad,FGSG_05646,,,PH-1,GzZC211,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2057,PHI:1897,UniProt,I1RH09,Broad,FGSG_03044,,,PH-1,GzZC212,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2058,PHI:1898,UniProt,A0A098DH20,EMBL,FGRAMPH1_01T11905,,,PH-1,GzZC213,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2059,PHI:1899,UniProt,A0A1C3YMI9,EMBL,FGRAMPH1_01T11731,,,PH-1,GzZC214,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2060,PHI:1900,UniProt,I1RND0,Broad,FGSG_05503,,,PH-1,GzZC215,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2061,PHI:1901,UniProt,A0A1C3YN50,EMBL,FGRAMPH1_01T14699,,,PH-1,GzZC216,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2062,PHI:1902,UniProt,I1RJS7,Broad,FGSG_04109,,,PH-1,GzZC217,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2063,PHI:1903,UniProt,A0A1C3YMR5,EMBL,FGRAMPH1_01T12613,,,PH-1,GzZC218,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2064,PHI:1904,UniProt,I1RHR0,Broad,FGSG_03322,,,PH-1,GzZC219,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2065,PHI:1905,UniProt,A0A1C3YMR5,EMBL,FGRAMPH1_01T12613,,,PH-1,GzZC220,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2066,PHI:1906,UniProt,I1RHN1,Broad,FGSG_03292,,,PH-1,GzZC221,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2067,PHI:1907,UniProt,I1RHJ0,Broad,FGSG_03246,,,PH-1,GzZC222,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2068,PHI:1908,UniProt,A0A098DHQ5,EMBL,FGRAMPH1_01T12365,,,PH-1,GzZC223,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2069,PHI:1909,UniProt,I1RHG6,Broad,FGSG_03219,,,PH-1,GzZC224,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2070,PHI:1910,UniProt,I1RHG2,Broad,FGSG_03214,,,PH-1,GzZC225,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2071,PHI:1911,UniProt,A0A098DHQ6,EMBL,FGRAMPH1_01T12319,,,PH-1,GzZC226,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2072,PHI:1912,UniProt,I1RHF1,Broad,FGSG_03201,,,PH-1,GzZC227,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2073,PHI:1913,UniProt,I1RP37,Broad,FGSG_05789,,,PH-1,GzZC228,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2074,PHI:1914,UniProt,I1RQ27,Broad,FGSG_06160,,,PH-1,GzZC229,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2075,PHI:1915,UniProt,I1RSL0,Broad,FGSG_07133,,,PH-1,GzZC230,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,reduced,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2076,PHI:1916,UniProt,A0A0E0SCZ1,EMBL,FGRAMPH1_01T23911,,,PH-1,GzZC231,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2077,PHI:1917,UniProt,I1RSE9,Broad,FGSG_07067,,,PH-1,GzZC232,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2078,PHI:1918,UniProt,I1RT69,Broad,FGSG_07368,,,PH-1,GzZC233,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2079,PHI:1919,UniProt,I1RCQ4,Broad,FGSG_01378,,,PH-1,GzZC234,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2080,PHI:1920,UniProt,I1RCK0,Broad,FGSG_01318,,,PH-1,GzZC235,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2081,PHI:1921,UniProt,I1RCH8,Broad,FGSG_01293,,,PH-1,GzZC236,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2082,PHI:1922,UniProt,A0A1C3YKR9,EMBL,FGRAMPH1_01T23489,,,PH-1,GzZC237,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2083,PHI:1923,UniProt,I1RHB3,Broad,FGSG_03159,,,PH-1,GzZC238,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2084,PHI:1924,UniProt,A0A098DHE1,EMBL,FGRAMPH1_01T12153,,,PH-1,GzZC239,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2085,PHI:1925,UniProt,I1RH59,Broad,FGSG_03102,,,PH-1,GzZC240,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2086,PHI:1926,UniProt,I1RKP6,Broad,FGSG_04459,,,PH-1,GzZC241,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2087,PHI:1927,UniProt,I1RR79,Broad,FGSG_06593,,,PH-1,GzZC242,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2088,PHI:1928,UniProt,I1RIR0,Broad,FGSG_03702,,,PH-1,GzZC243,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2089,PHI:1929,UniProt,I1RIP1,Broad,FGSG_03683,,,PH-1,GzZC244,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2090,PHI:1930,UniProt,A0A0E0RT42,EMBL,FGRAMPH1_01T05223,,,PH-1,GzZC245,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2091,PHI:1931,UniProt,I1REJ4,Broad,FGSG_02083,,,PH-1,GzZC246,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2092,PHI:1932,UniProt,A0A0E0RSS5,EMBL,FGRAMPH1_01T04987,,,PH-1,GzZC247,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2093,PHI:1933,UniProt,I1RC73,Broad,FGSG_01176,,,PH-1,GzZC248,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2094,PHI:1934,UniProt,I1RC69,Broad,FGSG_01172,,,PH-1,GzZC249,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2095,PHI:1935,UniProt,I1RFP7,Broad,FGSG_02531,,,PH-1,GzZC250,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2096,PHI:1936,UniProt,A0A0E0RU02,EMBL,FGRAMPH1_01T05845,,,PH-1,GzZC251,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2097,PHI:1937,UniProt,I1RN12,Broad,FGSG_05370,,,PH-1,GzZC252,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2098,PHI:1938,UniProt,A0A098E2A1,EMBL,FGRAMPH1_01T17693,,,PH-1,GzZC253,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2099,PHI:1939,UniProt,A0A0E0SME8,EMBL,FGRAMPH1_01T17647,,,PH-1,GzZC254,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2100,PHI:1940,UniProt,A0A098E4K9,EMBL,FGRAMPH1_01T17519,,,PH-1,GzZC255,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2101,PHI:1941,UniProt,A0A0E0S1U8,EMBL,FGRAMPH1_01T11341,,,PH-1,GzZC256,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2102,PHI:1942,UniProt,I1RG47,Broad,FGSG_02696,,,PH-1,GzZC257,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2103,PHI:1943,UniProt,A0A098DQP4,EMBL,FGRAMPH1_01T27387,,,PH-1,GzZC258,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2104,PHI:1944,UniProt,A0A0E0RUE3,EMBL,FGRAMPH1_01T06127,,,PH-1,GzZC259,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2105,PHI:1945,UniProt,I1RGK4,Broad,FGSG_02874,,,PH-1,GzZC260,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2106,PHI:1946,UniProt,I1RGI7,Broad,FGSG_02854,,,PH-1,GzZC261,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2107,PHI:1947,UniProt,A0A0E0S4E9,EMBL,FGRAMPH1_01T13141,,,PH-1,GzZC262,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2108,PHI:1948,UniProt,I1RI81,Broad,FGSG_03508,,,PH-1,GzZC263,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2109,PHI:1949,UniProt,A0A098DIL8,EMBL,FGRAMPH1_01T12993,,,PH-1,GzZC264,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2110,PHI:1950,UniProt,I1RDP6,Broad,FGSG_01760,,,PH-1,GzZC265,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2111,PHI:1951,UniProt,I1RDL5,Broad,FGSG_01724,,,PH-1,GzZC266,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2112,PHI:1952,UniProt,I1RDH3,Broad,FGSG_01669,,,PH-1,GzZC267,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2113,PHI:1953,UniProt,I1RKB4,Broad,FGSG_04311,,,PH-1,GzZC268,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2114,PHI:1954,UniProt,I1RMG7,Broad,FGSG_05157,,,PH-1,GzZC269,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2115,PHI:1955,UniProt,A0A1C3YJY3,EMBL,FGRAMPH1_01T16779,,,PH-1,GzZC270,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2116,PHI:1956,UniProt,I1RLT2,Broad,FGSG_04901,,,PH-1,GzZC271,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2117,PHI:1957,UniProt,A0A1C3YJG4,EMBL,FGRAMPH1_01T16567,,,PH-1,GzZC272,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2118,PHI:1958,UniProt,I1RMD1,Broad,FGSG_05120,,,PH-1,GzZC273,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2119,PHI:1959,UniProt,A0A0E0SMG6,EMBL,FGRAMPH1_01T17013,,,PH-1,GzZC274,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2120,PHI:1960,UniProt,I1RDE2,Broad,FGSG_01638,,,PH-1,GzZC275,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2121,PHI:1961,UniProt,I1RD74,Broad,FGSG_01564,,,PH-1,GzZC276,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2122,PHI:1962,UniProt,V6QY41,Broad,FGSG_01562,,,PH-1,GzZC277,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2123,PHI:1963,UniProt,A0A1C3YKW2,EMBL,FGRAMPH1_01T22453,,,PH-1,GzZC278,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2124,PHI:1964,UniProt,I1RQU2,Broad,FGSG_06442,,,PH-1,GzZC279,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2125,PHI:1965,UniProt,I1RQT6,Broad,FGSG_06436,,,PH-1,GzZC280,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2126,PHI:1966,UniProt,I1RB21,Broad,FGSG_00725,,,PH-1,GzZC281,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2127,PHI:1967,UniProt,I1RB16,Broad,FGSG_00719,,,PH-1,GzZC282,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2128,PHI:1968,UniProt,I1RB12,Broad,FGSG_00713,,,PH-1,GzZC283,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2129,PHI:1969,UniProt,A0A0E0RTX3,EMBL,FGRAMPH1_01T05787,,,PH-1,GzZC284,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2130,PHI:1970,UniProt,I1RFB5,Broad,FGSG_02384,,,PH-1,GzZC285,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2131,PHI:1971,UniProt,I1RF99,Broad,FGSG_02368,,,PH-1,GzZC286,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2132,PHI:1972,UniProt,I1RF57,Broad,FGSG_02323,,,PH-1,GzZC287,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2133,PHI:1973,UniProt,I1RF54,Broad,FGSG_02320,,,PH-1,GIP2,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2134,PHI:1974,UniProt,I1RQN6,Broad,FGSG_06382,,,PH-1,GzZC289,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2135,PHI:1975,UniProt,A0A1C3YKK4,EMBL,FGRAMPH1_01T20037,,,PH-1,GzZC290,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2136,PHI:1976,UniProt,I1RLP8,Broad,FGSG_04862,,,PH-1,GzZC291,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2137,PHI:1977,UniProt,A0A0E0SPL9,EMBL,FGRAMPH1_01T16411,,,PH-1,GzZC292,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2138,PHI:1978,UniProt,I1RLK0,Broad,FGSG_04803,,,PH-1,GzZC293,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2139,PHI:1979,UniProt,I1RLI4,Broad,FGSG_04786,,,PH-1,GzZC294,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2140,PHI:1980,UniProt,I1RLF1,Broad,FGSG_04747,,,PH-1,GzZC295,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2141,PHI:1981,UniProt,I1RIY9,Broad,FGSG_03786,,,PH-1,GzZC296,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2142,PHI:1982,UniProt,I1RIT3,Broad,FGSG_03727,,,PH-1,GzZC297,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2143,PHI:1983,UniProt,I1RB90,Broad,FGSG_00800,,,PH-1,GzZC298,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2144,PHI:1984,UniProt,I1RB67,Broad,FGSG_00774,,,PH-1,GzZC299,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2145,PHI:1985,UniProt,I1RAT9,Broad,FGSG_00625,,,PH-1,GzZC300,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2146,PHI:1986,UniProt,I1RA77,Broad,FGSG_00404,,,PH-1,GzZC301,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2147,PHI:1987,UniProt,I1RAP2,Broad,FGSG_00574,,,PH-1,GzZC302,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2148,PHI:1988,UniProt,I1RAP1,Broad,FGSG_00573,,,PH-1,GzZC303,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,defective,reduced,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2149,PHI:1989,UniProt,I1R9Z6,Broad,FGSG_00313,,,PH-1,GzZC304,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2150,PHI:1990,UniProt,I1R9K3,Broad,FGSG_00147,,,PH-1,GzZC305,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2151,PHI:1991,UniProt,I1R9K1,Broad,FGSG_00144,,,PH-1,GzZC306,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2152,PHI:1992,UniProt,I1R983,Broad,FGSG_00011,,,PH-1,GzZC307,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2153,PHI:1993,UniProt,I1R9S7,Broad,FGSG_00235,,,PH-1,GzZC308,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2154,PHI:1994,UniProt,I1R9S1,Broad,FGSG_00227,,,PH-1,GzZC309,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2155,PHI:1995,UniProt,A0A1C3YI01,EMBL,FGRAMPH1_01T00531,,,PH-1,GzZC310,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2156,PHI:1996,UniProt,I1R9R2,Broad,FGSG_00217,,,PH-1,GzZC311,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2157,PHI:1997,UniProt,I1R9G3,Broad,FGSG_00102,,,PH-1,GzZC312,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2158,PHI:1998,UniProt,I1R9B9,Broad,FGSG_00052,,,PH-1,GzZC313,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2159,PHI:1999,UniProt,A0A1C3YHZ9,EMBL,FGRAMPH1_01T00245,,,PH-1,GzZC314,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2160,PHI:2000,UniProt,I1R9D4,Broad,FGSG_00069,,,PH-1,GzZC315,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2161,PHI:2001,UniProt,A0A098CZE9,EMBL,FGRAMPH1_01T00347,,,PH-1,GzZC316,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,22028654,PubMed,10.1371/journal.ppat.1002310,,ee2443@snu.ac.kr,,Son,2011,,,,2011-05-04,MU,,,,,,,,,,,,,
,,Record 2162,PHI:2002,UniProt,G4NAC3,EMBL,EDK00306,,,Guy11,TIG1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,histone deacetylation,,,Mps1 pathway,loss of pathogenicity,,no,no,yes,delayed symptoms; reduced symptoms; delayed sporulation; reduced sporulation; wild type; no data found;,reduced,,reduced on CM medium,,no,,,,,,strong defense response,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2163,PHI:2002,UniProt,G4NAC3,EMBL,EDK00306,,,Guy11,TIG1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,histone deacetylation,,,,loss of pathogenicity,,no,no,yes,,reduced,,,,no,,,,,,enhance callose deposition,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2164,PHI:2002,UniProt,G4NAC3,EMBL,EDK00306,,,70-15,TIG1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,histone deacetylation,,,Mps1 pathway,loss of pathogenicity,,,,,,reduced; defective,,reduced on CM medium,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2165,PHI:2002,UniProt,G4NAC3,EMBL,EDK00306,,,Guy11,TIG1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4679,Allium cepa (related: onion),,,,bulb,histone deacetylation,,,,loss of pathogenicity,,no,yes,yes,,,,,,no,,,,,,strong defense response,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria. Tissue epidermal cells of bulb scales.,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2166,PHI:2003,,no data found,EMBL,EDK04728,,,Ku80,SET3,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,histone deacetylation,,,Mps1 pathway,loss of pathogenicity,,,,,,reduced; defective,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2167,PHI:2004,,no data found,EMBL,EDJ98032,,,Ku80,SNT1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,histone deacetylation,,,Mps1 pathway,loss of pathogenicity,,,,,,reduced; defective,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2168,PHI:2005,UniProt,G4MUC7,EMBL,EDK04649,,,70-15,HOS2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,histone deacetylation,,,Mps1 pathway,loss of pathogenicity,,,,,,reduced; defective,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2169,PHI:2003,,no data found,EMBL,EDK04728,,,Ku80,SET3,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,histone deacetylation,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2170,PHI:2003,,no data found,EMBL,EDK04728,,,Ku80,SET3,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Plaisant,,,leaf,histone deacetylation,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2171,PHI:2004,,no data found,EMBL,EDJ98032,,,Ku80,SNT1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,histone deacetylation,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2172,PHI:2005,UniProt,G4MUC7,EMBL,EDK04649,,,70-15,HOS2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,histone deacetylation,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,part of histone deacetylase corepressor complex; increased sensitivity to oxidative stress; mutant makes appressoria,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2173,PHI:2006,UniProt,G4MS03,EMBL,EDJ98541,,,70-15,HST1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,histone deacetylation,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,no comments,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2174,PHI:2007,,no data found,EMBL,EDK06449,,,70-15,HOS4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,histone deacetylation,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,no comments,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2175,PHI:2008,UniProt,G4MS03,EMBL,EDJ98541,,,70-15,HST1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,histone deacetylation,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,no comments,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2176,PHI:2009,UniProt,G4MPI2,EMBL,EDK06449,,,70-15,HOS4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,histone deacetylation,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,no comments,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2177,PHI:2010,,no data found,EMBL,EDK02244,,,,HDA1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,histone deacetylation,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,no comments,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2178,PHI:2011,,no data found,EMBL,EDJ9334,,,,HOS3,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,histone deacetylation,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,no comments,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2179,PHI:2012,,no data found,EMBL,EDK02244,,,,HDA1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,histone deacetylation,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,no comments,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2180,PHI:2013,,no data found,EMBL,EDJ9334,,,,HOS3,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,histone deacetylation,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,,20675574,PubMed,10.1105/tpc.110.074302,,jinrong@purdue.edu,no comments,Sheng-Li Ding,2010,,,Batch001,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2181,PHI:2014,UniProt,B9WZW9,EMBL,AB498873,,,Ina168,AVR-Pia,"chromosome 7, 36.5 kb from telomere; Contig2 (Supercontig 5.117)",,,,,,318829,Magnaporthe oryzae,,JS153,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Aichi asahi,,,,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,"sexual cross, sequencing of resistance conferring allele",,,RP,17115220,PubMed,10.1007/s00438-006-0179-8,,xbzheng@njau.edu.cn,no comments,Q. H. Chen,2007,,Chen_2007_MGG-0024721668,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2182,PHI:2016,UniProt,G4NCA2,Broad,MGG_01099,,,70-15,PTH2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,peroxisomal carnitine acetyl transferase; lipid reserve mobilization,,,,loss of pathogenicity,,no,yes,,,reduced,,reduced,wild type,no,PTH2 gene expression induced by: glucose; ethanol; acetate; olive oil; oleic acid; triolein; scytalone; sucrose,CAS:50-99-7; CAS:64-17-5; CAS:71-50-1; CAS:8001-25-0; CAS:112-80-1; CAS:122-32-7; CAS:49598-85-8; CAS:57-50-1,,,,,gene disruption; gene complementation,,,RP,16824094,PubMed,10.1111/j.1365-2958.2006.05209.x,,n.j.talbot@exeter.ac.uk,"Elevated expression of PTH2 transcript was observed when the fungus was grown on ethanol, acetate, olive oil, oleic acid, triolein or glycerol as sole carbon sources compared with growth on glucose; No significant difference in appressorial turgor between the wild type and PTH2 mutant was found in presence of glycerol; No restoration of lesion formation was observed in PTH2 mutants by addition of Scytalone [data not shown]; The ability to cause rice blast symptoms was partly restored to the PTH2 mutatnt in presence of either glucose or sucrose; Lipid mobilization to appressorium in PTH2 mutant was restored to near normal levels, and penetration hyphae were observed invading rice tissue when the fungus was incubated in the presence of glucose",Gurpreet K. Bhambra,2006,,Bhambra-2006-Peroxisomal carnitin-0319483498,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2183,PHI:2016,UniProt,G4NCA2,Broad,MGG_01099,,,70-15,PTH2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,peroxisomal carnitine acetyl transferase; lipid reserve mobilization,,,,loss of pathogenicity,,,,,,,,reduced,,no,PTH2 gene expression induced by: glucose; ethanol; acetate; olive oil; oleic acid; triolein; scytalone; sucrose,CAS:50-99-7; CAS:64-17-5; CAS:71-50-1; CAS:8001-25-0; CAS:112-80-1; CAS:122-32-7; CAS:49598-85-8; CAS:57-50-1,,,,,gene disruption,,,RP,16824094,PubMed,10.1111/j.1365-2958.2006.05209.x,,n.j.talbot@exeter.ac.uk,"Elevated expression of PTH2 transcript was observed when the fungus was grown on ethanol, acetate, olive oil, oleic acid, triolein or glycerol as sole carbon sources compared with growth on glucose; No significant difference in appressorial turgor between the wild type and PTH2 mutant was found in presence of glycerol; No restoration of lesion formation was observed in PTH2 mutants by addition of Scytalone [data not shown]; The ability to cause rice blast symptoms was partly restored to the PTH2 mutatnt in presence of either glucose or sucrose; Lipid mobilization to appressorium in PTH2 mutant was restored to near normal levels, and penetration hyphae were observed invading rice tissue when the fungus was incubated in the prsence of glucose",Gurpreet K. Bhambra,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2184,PHI:2017,UniProt,G4MX10,Broad,MGG_01215,,,70-15,COM1,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,transcription regulator,,,,reduced virulence,,no,yes,yes,full blast lesion rarely formed; lesions smaller,aberrant; reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19958144,PubMed,10.1094/MPMI-23-1-0112,,pengyl@cau.edu.cn,no comments,Jun Yang,2010,,Com1_MPMI-0127513092,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2185,PHI:2017,UniProt,G4MX10,Broad,MGG_01215,,,70-15,COM1,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. E9,,,leaf,transcription regulator,,,,reduced virulence,,,,,full blast lesion rarely formed; lesions smaller,aberrant; reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19958144,PubMed,10.1094/MPMI-23-1-0112,,pengyl@cau.edu.cn,no comments,Jun Yang,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2186,PHI:2017,UniProt,G4MX10,Broad,MGG_01215,,,70-15,COM1,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4679,Allium cepa (related: onion),,,,plant epidermis,transcription regulator,,,,reduced virulence,,no,yes,yes,,,,,wild type,no,,,,,,,gene deletion: full,,,RP,19958144,PubMed,10.1094/MPMI-23-1-0112,,pengyl@cau.edu.cn,no comments,Jun Yang,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2187,PHI:2018,UniProt,G4N054,Broad,MGG_05332,,,70-15,MoPLC2,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,seedling; leaf,,,,calcium signalling,loss of pathogenicity,,yes (aberrant appressorium development),yes,yes/no (conflicting statement in paper),tiny necrotic lesions,reduced,,wild type,wild type,no,KCl; NACl; calcofluor,KCl: CAS:7447-40-7; NaCl: CAS:7681-52-9; calcofluor: CAS:91-44-1,,,,,gene deletion: full; gene complementation,,,RP,21237279,PubMed,10.1016/j.fgb.2011.01.001,,yonglee@snu.ac.kr,no comments,Jinhee Choi,2011,,Differential roles of the phospholipase C_FGB-2309032196,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2188,PHI:2019,UniProt,G4MWU9,Broad,MGG_08315,,,70-15,MoPLC3,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,seedling; leaf,,,,calcium signalling,loss of pathogenicity,,yes (aberrant appressorium development),yes,yes/no (conflicting statement in paper),tiny necrotic lesions,reduced,,wild type,wild type,no,KCl; NACl; calcofluor,KCl: CAS:7447-40-7; NaCl: CAS:7681-52-9; calcofluor: CAS:91-44-1,,,,,gene deletion: full; gene complementation,,,RP,21237279,PubMed,10.1016/j.fgb.2011.01.001,,yonglee@snu.ac.kr,no comments,Jinhee Choi,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2189,PHI:2020,UniProt,Q4P9D3,GenBank,XP_759427,,,,Tup1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,transcription repression,,,pheromone responsive pathway,reduced virulence,yes,yes,yes,no,"tumor size reduced, less mortality",,reduced,reduced,reduced,no,pheromone a1; pheromone a2; DMSO,DMSO: CAS:67-68-5,,,,,gene deletion: full; gene complementation,,,RP,21909277,PubMed,10.1371/journal.ppat.1002235,,joibecor@upo.es,no comments,Alberto Elias-Villalobos,2011,,Elias-Villalobos-2011-The general transcri-3196883716,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2190,PHI:2020,UniProt,Q4P9D3,GenBank,XP_759427,,,,Tup1,,,,,,,5270,Ustilago maydis,,SG200,smut (maize),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling; leaf,transcription repression,,,pheromone responsive pathway,reduced virulence,yes,yes,yes,no,,,,,,no,pheromone a1; pheromone a2; DMSO,DMSO: CAS:67-68-5,,,,,gene deletion: full; gene complementation,,,RP,21909277,PubMed,10.1371/journal.ppat.1002235,,joibecor@upo.es,no comments,Alberto Elias-Villalobos,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2191,PHI:2020,UniProt,Q4P9D3,GenBank,XP_759427,,,,Tup1,,,,,,,5270,Ustilago maydis,,FBD11,smut (maize),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf; flower,transcription repression,,,pheromone responsive pathway,loss of pathogenicity,yes,yes,yes,no,tumor size reduced,,,reduced,reduced,no,pheromone a1; pheromone a2; DMSO,DMSO: CAS:67-68-5,,,,,gene deletion: full; gene complementation,,,RP,21909277,PubMed,10.1371/journal.ppat.1002235,,joibecor@upo.es,no comments,Alberto Elias-Villalobos,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2192,PHI:2020,UniProt,Q4P9D3,GenBank,XP_759427,,,,Tup1,,,,,,,5270,Ustilago maydis,,HA103,smut (maize),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf; flower,transcription repression,,,pheromone responsive pathway,unaffected pathogenicity,no,no,no,no,,,,reduced,reduced,no,pheromone a1; pheromone a2; DMSO,DMSO: CAS:67-68-5,,,,,gene deletion: full; gene complementation,,,RP,21909277,PubMed,10.1371/journal.ppat.1002235,,joibecor@upo.es,no comments,Alberto Elias-Villalobos,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2193,PHI:2020,UniProt,Q4P9D3,GenBank,XP_759427,,,,Tup1,,,,,,,5270,Ustilago maydis,,CL13,smut (maize),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf; flower,transcription repression,,,pheromone responsive pathway,reduced virulence,no,no,no,no,,,,reduced,reduced,no,pheromone a1; pheromone a2; DMSO,DMSO: CAS:67-68-5,,,,,gene deletion: full; gene complementation,,,RP,21909277,PubMed,10.1371/journal.ppat.1002235,,joibecor@upo.es,no comments,Alberto Elias-Villalobos,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2194,PHI:2021,UniProt,G4N6D4,GenBank,MGG_06564,,,70-15,Pac2,,,,,,,5270,Ustilago maydis,,SG200,smut (maize),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,transcription repression,,,pheromone responsive pathway,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,21909277,PubMed,10.1371/journal.ppat.1002235,,joibecor@upo.es,no comments,Alberto Elias-Villalobos,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2195,PHI:2022,UniProt,Q12634,GenBank,MGG_02252.6,,,70-15,BUF1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Express,,,leaf,data not found,,,malanin biosynthesis,loss of pathogenicity,,,yes,yes,,,,,,no,tricyclazole,CAS:41814-78-2,,,,,gene disruption; gene complementation,,,RP,17142568,PubMed,10.1128/EC.00330-05,,marc-henri.lebrun@bayercropscience.com.,Tricyclazole-treated appressoria were not melanized and unable to penetrate plant tissues or cellophane.,Isabelle Fudal,2007,,Fudal-2007-Expression of Magnap-1886404612,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2196,PHI:2022,UniProt,Q12634,GenBank,MGG_02252.6,,,70-15,BUF1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,data not found,,,malanin biosynthesis,loss of pathogenicity,,,yes,,,,,,,no,tricyclazole,CAS:41814-78-2,,,,,gene disruption; gene complementation,,,RP,17142568,PubMed,10.1128/EC.00330-05,,marc-henri.lebrun@bayercropscience.com.,Tricyclazole-treated appressoria were not melanized and unable to penetrate plant tissues or cellophane.,Isabelle Fudal,2007,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2197,PHI:2025,UniProt,G4MQZ9,Broad,MG02376.4,,,,HDL1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,intracellular triacylglycerol lipases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,LIPID_MPMI-1920425220,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2198,PHI:2027,UniProt,G4NJL1,Broad,MG02622.4,,,,TGL1-1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,intracellular triacylglycerol lipases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2199,PHI:2028,UniProt,G4NBI7,Broad,MG00528.4,,,,TGL1-2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,intracellular triacylglycerol lipases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2200,PHI:2029,UniProt,G4NEK6,Broad,MG00773.4,,,,TGL2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,intracellular triacylglycerol lipases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2201,PHI:2030,UniProt,G4N492,Broad,MG05933.4,,,,TGL3-1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,intracellular triacylglycerol lipases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2202,PHI:2031,UniProt,Q0PND3,Broad,MG09880.4,,,,TGL3-2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,intracellular triacylglycerol lipases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2203,PHI:2030,UniProt,G4N492,Broad,MG05933.4,,,,TGL3-1,,,,,,PHI:2031,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,intracellular triacylglycerol lipases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2204,PHI:2031,UniProt,Q0PND3,Broad,MG09880.4,,,,TGL3-2,,,,,,PHI:2030,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,intracellular triacylglycerol lipases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2205,PHI:2032,UniProt,G4NGA7,Broad,MG10414.4,,,,VTL1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,intracellular triacylglycerol lipases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2206,PHI:2033,UniProt,G4NBI6,Broad,MG00529.4,,,,MgPex6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,peroxisome biogenesis,,,,loss of pathogenicity,,yes,yes,yes,no disease lesions,reduced,,reduced,reduced; aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2207,PHI:2034,UniProt,G4MZY1,Broad,MG06148.4,,,,MFP1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,beta-oxidation,,,,reduced virulence,,,,,reduction in disease lesion development,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,17506326,PubMed,10.1094/MPMI-20-5-0475,,n.j.talbot@exeter.ac.uk,no comments,Zheng-Yi Wang,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2208,PHI:2035,UniProt,Q52EB3,EMBL,ABB46201,,,,ATG1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,serine/threonine kinase; autophagy,,,,loss of pathogenicity,yes,no,yes,,low disease severity; few and isolated lesions,reduced; aberrant,,reduced,reduced,no,PMSF (phenylmethylsulfonyl fluoride),CAS:329-98-6,,,,,gene deletion: full; gene complementation,,,RP,17416896,PubMed,10.1128/EC.00011-07,,fuchenglin@zju.edu.cn,no comments,Xiao-Hong Liu,2007,,Liu-2007-Involvement of a Mag-2389712388,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2209,PHI:2035,UniProt,Q52EB3,EMBL,ABB46201,,,,ATG1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. ZJ-8,,,leaf,serine/threonine kinase; autophagy,,,,loss of pathogenicity,yes,no,yes,,low disease severity; few and isolated lesions,reduced; aberrant,,reduced,reduced,no,PMSF (phenylmethylsulfonyl fluoride),CAS:329-98-6,,,,,gene deletion: full; gene complementation,,,RP,17416896,PubMed,10.1128/EC.00011-07,,fuchenglin@zju.edu.cn,no comments,Xiao-Hong Liu,2007,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2210,PHI:2035,UniProt,Q52EB3,EMBL,ABB46201,,,,ATG1,,,,,,,318829,Magnaporthe oryzae,,2539,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,serine/threonine kinase; autophagy,,,,loss of pathogenicity,yes,no,yes,,low disease severity; few and isolated lesions,reduced; aberrant,,reduced,reduced,no,PMSF (phenylmethylsulfonyl fluoride),CAS:329-98-6,,,,,gene deletion: full; gene complementation,,,RP,17416896,PubMed,10.1128/EC.00011-07,,fuchenglin@zju.edu.cn,no comments,Xiao-Hong Liu,2007,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2211,PHI:2035,UniProt,Q52EB3,EMBL,ABB46201,,,,ATG1,,,,,,,318829,Magnaporthe oryzae,,2539,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. ZJ-8,,,leaf,serine/threonine kinase; autophagy,,,,loss of pathogenicity,yes,no,yes,,low disease severity; few and isolated lesions,reduced; aberrant,,reduced,reduced,no,PMSF (phenylmethylsulfonyl fluoride),CAS:329-98-6,,,,,gene deletion: full; gene complementation,,,RP,17416896,PubMed,10.1128/EC.00011-07,,fuchenglin@zju.edu.cn,no comments,Xiao-Hong Liu,2007,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2212,PHI:2036,UniProt,Q2LD94,EMBL,ABC60049.1,,,B157,RGS1,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,negative regulator of appressorium development; negative regulators of G-protein signaling,,,G-protein signalling,increased virulence (hypervirulence),,,,,,increased,,increased,increased,no,8-Br-cAMP; IBMX,8-Br-cAMP: CAS:76939-46-3; IBMX: CAS:28822-58-4,,,,,gene deletion: full; gene complementation,,,RP,17255942,PubMed,10.1038/sj.emboj.7601536,,naweed@tll.org.sg,no comments,Hao Liu,2007,,Liu-2007-Rgs1 regulates multi-2406493956,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2213,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,LY-130,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,MoRic8-1855511044,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2214,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-3,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2215,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-10,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2216,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-8,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2217,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2218,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,LY-130-R1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2219,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,LY-130-R4,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2220,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-10C,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2221,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-10C3,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2222,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,LY-130,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2223,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-3,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2224,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-10,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2225,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-8,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2226,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2227,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,LY-130-R1,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2228,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,LY-130-R4,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2229,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-10C,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2230,PHI:2037,UniProt,G4N6E0,GenBank,XP_001405357,,,Guy11,MoRic8,,,,,,,318829,Magnaporthe oryzae,,Q-10C3,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,G-protein signaling,,,G-protein signalling,loss of pathogenicity,yes,yes,yes,,,reduced,reduced,increased; aberrant,wild type,no,"cAMP; IBMX; 1,16-hexadecanediol(diol)","cAMP: CAS:60-92-4; IBMX: CAS:28822-58-4; 1,16-hexadecanediol(diol): CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,RP,20121453,PubMed,10.1094/MPMI-23-3-0317,,,no comments,Ya Li,2010,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2231,PHI:2038,UniProt,G4MQZ2,GenBank,MGG_02370.6,,,70-15,Mir1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,,,,,unaffected pathogenicity,,no,no,no,typical blast lesions (data not shown),wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,RP,17427815,PubMed,10.1094/MPMI-20-4-0448,,jinrong@purdue.edu,no comments,Lei Li,2007,,MPMI_ding-1098208772,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2232,PHI:2038,UniProt,G4MQZ2,GenBank,MGG_02370.6,,,70-15,Mir1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4679,Allium cepa (related: onion),,,,leaf,,,,,unaffected pathogenicity,,no,no,no,typical blast lesions (data not shown),wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,RP,17427815,PubMed,10.1094/MPMI-20-4-0448,,jinrong@purdue.edu,no comments,Lei Li,2007,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2233,PHI:2038,UniProt,G4MQZ2,GenBank,MGG_02370.6,,,70-15,Mir1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise; subsp. vulgare cv. Kindred,,,seedling; leaf,,,,,unaffected pathogenicity,,no,no,no,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,RP,17427815,PubMed,10.1094/MPMI-20-4-0448,,jinrong@purdue.edu,no comments,Lei Li,2007,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2234,PHI:2039,UniProt,Q069J4,EMBL,DQ985585,,,70-15,Con7p,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,encode transcription factor,,,,loss of pathogenicity,,yes,yes,,,reduced; aberrant,,wild type,aberrant,no,"cAMP; 1,16-hexadecanediol(diol); glucanex; nikkomycin Z","cAMP: CAS:60-92-4; 1,16-hexadecanediol(diol): CAS:7735-42-4; glucanex: CAS:9073-49-8; nikkomycin Z: CAS:59456-70-1",,,,,promotor mutation; gene complementation,,,RP,17378924,PubMed,10.1111/j.1365-2958.2007.05643.x,,foster@ibwf.de,no comments,Dominik Odenbach,2007,,Odenbach-2007-The transcription fa-3916454148,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2235,PHI:2039,UniProt,Q069J4,EMBL,DQ985585,,,70-15,Con7p,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling,encode transcription factor,,,,loss of pathogenicity,,yes,yes,,,reduced; aberrant,,wild type,aberrant,no,"cAMP; 1,16-hexadecanediol(diol); glucanex; nikkomycin Z","cAMP: CAS:60-92-4; 1,16-hexadecanediol(diol): CAS:7735-42-4; glucanex: CAS:9073-49-8; nikkomycin Z: CAS:59456-70-1",,,,,promotor mutation; gene complementation,,,RP,17378924,PubMed,10.1111/j.1365-2958.2007.05643.x,,foster@ibwf.de,no comments,Dominik Odenbach,2007,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2236,PHI:2041,,no data found,EMBL,AF463528.1,,,Guy11,AVR1-CO39,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,host specificity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,RP,20507436,PubMed,10.1111/J.1364-3703.2006.00325.X,,farman@uky.edu,no comments,REBECCA PEYYALA,2006,,Peyyala-2006-Magnaporthe oryzae i-0504023658,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2237,PHI:2041,,no data found,EMBL,AF463528.1,,,Guy11,AVR1-CO39,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. 51583,,,seedling,host specificity,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,RP,20507436,PubMed,10.1111/J.1364-3703.2006.00325.X,,farman@uky.edu,no comments,REBECCA PEYYALA,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2238,PHI:2042,UniProt,Q3Y5V5,EMBL,DQ156556,,,B157,ABC3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,multidrug resistance; protection from oxidative stress,,,,loss of pathogenicity,yes,no,yes,yes,,wild type,reduced,reduced,aberrant,no,glycerol; valinomycin; verapamil; actinomycin D; benomyl; brefeldin A; gramicidin D; leptomycin B; fluconazole; itraconazole; sorbitol; sucrose; sodium chloride; hydrogen peroxide; paraquat; menadione; diphenyleneiodonium; nordihydroguaiaretic acid; rotenone; ascorbate; N-acetylcysteine,"glycerol: CAS:56-81-5; valinomycin: CAS:2001-95-8; verapamil: CAS:52-11-4; actinomycin D: CAS:50-76-0; benomyl: CHEBI:3015, CAS:17804-35-2; brefeldin A: CAS:20350-15-6; gramicidin D: CAS:1393-88-0; leptomycin B: CAS:87081-35-4; fluconazole: CHEBI:46081, CAS:86386-73-4; itraconazole: CAS:84625-61-6; sorbitol: CAS:50-70-4; sucrose: CAS:57-50-1; sodium chloride: CAS:7681-52-9; hydrogen peroxide: CAS:7722-84-1; paraquat: CAS:1910-42-5; menadione: CAS:58-27-5; diphenyleneiodonium: CAS:4673-26-1; nordihydroguaiaretic acid: CAS:500-38-9; rotenone: CAS:83-79-4; ascorbate: CAS:134-03-2; N-acetylcysteine: CAS:616-91-1",,,,failed to elicit proper hypersensitive reaction,gene deletion: full; gene complementation,,,RP,17189344,PubMed,10.1105/tpc.105.037861,,naweed@tll.org.sg,no comments,Chuan Bao Sun,2006,,Sun-2006-A multidrug resistan-1275766890,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2239,PHI:2042,UniProt,Q3Y5V5,EMBL,DQ156556,,,B157,ABC3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. NIL127,,,seedling,multidrug resistance; protection from oxidative stress,,,,loss of pathogenicity,yes,no,yes,yes,,wild type,reduced,reduced,aberrant,no,glycerol; valinomycin; verapamil; actinomycin D; benomyl; brefeldin A; gramicidin D; leptomycin B; fluconazole; itraconazole; sorbitol; sucrose; sodium chloride; hydrogen peroxide; paraquat; menadione; diphenyleneiodonium; nordihydroguaiaretic acid; rotenone; ascorbate; N-acetylcysteine,"glycerol: CAS:56-81-5; valinomycin: CAS:2001-95-8; verapamil: CAS:52-11-4; actinomycin D: CAS:50-76-0; benomyl: CHEBI:3015, CAS:17804-35-2; brefeldin A: CAS:20350-15-6; gramicidin D: CAS:1393-88-0; leptomycin B: CAS:87081-35-4; fluconazole: CHEBI:46081, CAS:86386-73-4; itraconazole: CAS:84625-61-6; sorbitol: CAS:50-70-4; sucrose: CAS:57-50-1; sodium chloride: CAS:7681-52-9; hydrogen peroxide: CAS:7722-84-1; paraquat: CAS:1910-42-5; menadione: CAS:58-27-5; diphenyleneiodonium: CAS:4673-26-1; nordihydroguaiaretic acid: CAS:500-38-9; rotenone: CAS:83-79-4; ascorbate: CAS:134-03-2; N-acetylcysteine: CAS:616-91-1",,,,failed to elicit proper hypersensitive reaction,gene deletion: full; gene complementation,,,RP,17189344,PubMed,10.1105/tpc.105.037861,,naweed@tll.org.sg,no comments,Chuan Bao Sun,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2240,PHI:2042,UniProt,Q3Y5V5,EMBL,DQ156556,,,B157,ABC3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Express,,,seedling,multidrug resistance; protection from oxidative stress,,,,loss of pathogenicity,yes,no,yes,yes,,wild type,reduced,reduced,aberrant,no,glycerol; valinomycin; verapamil; actinomycin D; benomyl; brefeldin A; gramicidin D; leptomycin B; fluconazole; itraconazole; sorbitol; sucrose; sodium chloride; hydrogen peroxide; paraquat; menadione; diphenyleneiodonium; nordihydroguaiaretic acid; rotenone; ascorbate; N-acetylcysteine,"glycerol: CAS:56-81-5; valinomycin: CAS:2001-95-8; verapamil: CAS:52-11-4; actinomycin D: CAS:50-76-0; benomyl: CHEBI:3015, CAS:17804-35-2; brefeldin A: CAS:20350-15-6; gramicidin D: CAS:1393-88-0; leptomycin B: CAS:87081-35-4; fluconazole: CHEBI:46081, CAS:86386-73-4; itraconazole: CAS:84625-61-6; sorbitol: CAS:50-70-4; sucrose: CAS:57-50-1; sodium chloride: CAS:7681-52-9; hydrogen peroxide: CAS:7722-84-1; paraquat: CAS:1910-42-5; menadione: CAS:58-27-5; diphenyleneiodonium: CAS:4673-26-1; nordihydroguaiaretic acid: CAS:500-38-9; rotenone: CAS:83-79-4; ascorbate: CAS:134-03-2; N-acetylcysteine: CAS:616-91-1",,,,failed to elicit proper hypersensitive reaction,gene deletion: full; gene complementation,,,RP,17189344,PubMed,10.1105/tpc.105.037861,,naweed@tll.org.sg,no comments,Chuan Bao Sun,2006,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2241,PHI:2043,UniProt,Q8NJ73,GenBank,AY124591,,,,XYL-6,,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sariceltik,,,seedling,"endo-beta-1,4-D-xylanase",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,16461639,PubMed,10.1128/AEM.72.2.986-993.2006,,wusc@ccrc.uga.edu,no comments,Sheng-Cheng Wu,2006,,Wu-2006-Identification of an-2198550890,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2242,PHI:2044,UniProt,G4MR98,GenBank,XP_362263,,,70-15,MoSOM1,Supercontig 16 of chromosome IV,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,transcriptional regulators,,,cAMP/PKA pathway,loss of pathogenicity,,yes,yes,,,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22144889,PubMed,10.1371/journal.ppat.1002385,,zhywang@zju.edu.cn,no comments,Xia Yan,2011,,Yan-2011-Two Novel Transcript-2441875204,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2243,PHI:2045,UniProt,G4MU85,GenBank,XP_001413674,,,70-15,MoCDTF1,Supercontig 27 of chromosome I,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,transcriptional regulators,,,cAMP/PKA pathway,loss of pathogenicity,,yes,yes,,,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22144889,PubMed,10.1371/journal.ppat.1002385,,zhywang@zju.edu.cn,no comments,Xia Yan,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2244,PHI:2044,UniProt,G4MR98,GenBank,XP_362263,,,70-15,MoSOM1,Supercontig 16 of chromosome IV,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,transcriptional regulators,,,cAMP/PKA pathway,loss of pathogenicity,,yes,yes,,,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22144889,PubMed,10.1371/journal.ppat.1002385,,zhywang@zju.edu.cn,no comments,Xia Yan,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2245,PHI:2045,UniProt,G4MU85,GenBank,XP_001413674,,,70-15,MoCDTF1,Supercontig 27 of chromosome I,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,transcriptional regulators,,,cAMP/PKA pathway,loss of pathogenicity,,yes,yes,,,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22144889,PubMed,10.1371/journal.ppat.1002385,,zhywang@zju.edu.cn,no comments,Xia Yan,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2246,PHI:2044,UniProt,G4MR98,GenBank,XP_362263,,,70-15,MoSOM1,Supercontig 16 of chromosome IV,,,,,PHI:2045,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,transcriptional regulators,,,cAMP/PKA pathway,loss of pathogenicity,,yes,yes,,,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,22144889,PubMed,10.1371/journal.ppat.1002385,,zhywang@zju.edu.cn,no comments,Xia Yan,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2247,PHI:2045,UniProt,G4MU85,GenBank,XP_001413674,,,70-15,MoCDTF1,Supercontig 27 of chromosome I,,,,,PHI:2044,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,transcriptional regulators,,,cAMP/PKA pathway,loss of pathogenicity,,yes,yes,,,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,22144889,PubMed,10.1371/journal.ppat.1002385,,zhywang@zju.edu.cn,no comments,Xia Yan,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2248,PHI:2044,UniProt,G4MR98,GenBank,XP_362263,,,70-15,MoSOM1,Supercontig 16 of chromosome IV,,,,,PHI:2045,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Golden Promise,,,leaf,transcriptional regulators,,,cAMP/PKA pathway,loss of pathogenicity,,yes,yes,,,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,22144889,PubMed,10.1371/journal.ppat.1002385,,zhywang@zju.edu.cn,no comments,Xia Yan,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2249,PHI:2045,UniProt,G4MU85,GenBank,XP_001413674,,,70-15,MoCDTF1,Supercontig 27 of chromosome I,,,,,PHI:2044,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Golden Promise,,,leaf,transcriptional regulators,,,cAMP/PKA pathway,loss of pathogenicity,,yes,yes,,,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,22144889,PubMed,10.1371/journal.ppat.1002385,,zhywang@zju.edu.cn,no comments,Xia Yan,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2250,PHI:2046,UniProt,G4N4W3,GenBank,XP_369431.2,,,70-15,MoMSB2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,,,,,loss of pathogenicity,,,,,,reduced,wild type,,wild type,no,"1,16-hexadecanediol; cyclic adenosine 3',5'-cyclophosphate; 3-isobutyl-1-methylxanthine",CAS:7735-42-4; CAS:60-92-4; CAS:28822-58-4,,,,,gene deletion: full,,,RP,22144889,PubMed,10.1371/journal.ppat.1002385,,zhywang@zju.edu.cn,"Defects in appressorium formation upon MoMSB2 deletion could not be restored by adding exogenous 1,16-hexadecanediol or Cyclic Adenosine 3',5'-cyclophosphate or 3-Isobutyl-1-methylxanthine.",Xia Yan,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2251,PHI:2046,UniProt,G4N4W3,GenBank,XP_369431.2,,,70-15,MoMSB2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,,,,,reduced,wild type,,wild type,no,"1,16-hexadecanediol; cyclic adenosine 3',5'-cyclophosphate; 3-isobutyl-1-methylxanthine",CAS:7735-42-4; CAS:60-92-4; CAS:28822-58-4,,,,,gene deletion: full,,,RP,22144889,PubMed,10.1371/journal.ppat.1002385,,zhywang@zju.edu.cn,,Xia Yan,2011,,,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2252,PHI:2047,,no data found,GenBank,EAA49142,,,70-15,MST7,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling; leaf,,,,MAPK pathway,loss of pathogenicity,,,yes,,,reduced,,,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,17214742,PubMed,10.1111/j.1365-2958.2006.05548.x,,jinrong@purdue.edu,no comments,Xinhua Zhao,2007,,Zhao-2007-A highly conserved M-1869628676,Batch002,2012-01-21,MC,,,,,,,,,,,,,
,,Record 2253,PHI:2048,UniProt,G4N4P0,GenBank,MGG_05133.6,,,70-15,MoCRZ1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,seedling; leaf,cell wall integrity,,,calcium/calcineurin signaling pathway,reduced virulence,,no,yes,no,small necrotic lesions or no lesions,reduced; aberrant,,reduced,wild type,no,NaCl; MnCl2; CaCl2; Congo red; calcofluor white; SDS; nikkomycin Z,NaCl: CAS:7647-14-5; MnCl2: CAS:64333-01-3; CaCl2: CAS:10043-52-4; calcofluor: CAS:91-44-1; nikkomycin Z: CAS:59456-70-1,,,,,gene deletion: full; gene complementation,,,RP,19111943,PubMed,10.1016/j.fgb.2008.11.010,,yonglee@snu.ac.kr,"When the mycelia of wild type and D mocrz1-2 mutant strains were treated with cell wall lys-ing enzyme, threefold more protoplasts were generated in the D mocrz1-2 mutant strain 90 min after treatment.",Jinhee Choi,2008,,19111943,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2254,PHI:2049,UniProt,G4MW47,EMBL,ABY26907.1,,,70-15,SSM2,chromosome I,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,siderophore biosynthesis,,,,reduced virulence,,no,no,no,,reduced,,reduced,wild type,no,H2O2; KO2; FeSO4; FeCl3; ferric citrate,H2O2: CAS:7722-84-1; Ko2: CAS:12030-88-5; FeSO4: CAS:7720-78-7; FeCl3: CAS:7705-08-0; ferric citrate: CAS:2338-05-8,,,,,gene deletion: full; gene complementation,,,RP,19171198,PubMed,10.1016/j.fgb.2008.12.004,,"eisfeld@ibwf.de , katei@gmx.de",a siderophore independent uptake mechanism for ferrous and ferric iron exists in M. grisea.,Carolin Hof,2008,,19171198,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2255,PHI:2050,UniProt,G4NF43,EMBL,BK005770.1,,,70-15,OMO1,chromosome IV,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,siderophore biosynthesis,,,,loss of pathogenicity,,,,,,reduced (absent),,reduced,wild type,no,H2O2; KO2; coprogen; FeSO4; FeCl3; ferric citrate; ferricrocin; ferrichrome,H2O2: CAS:7722-84-1; Ko2: CAS:12030-88-5; FeSO4: CAS:7720-78-7; FeCl3: CAS:7705-08-0; ferric citrate: CAS:2338-05-8; coprogen: CAS:31418-71-0; ferricrocin: CAS:23086-46-6; ferrichrome: CAS:15630-64-5,,,,,gene deletion: full; gene complementation,,,RP,19171198,PubMed,10.1016/j.fgb.2008.12.004,,"eisfeld@ibwf.de , katei@gmx.de",a siderophore independent uptake mechanism for ferrous and ferric iron exists in M. grisea. For pre-penetration defect 'no data found' as no conidiation; after complemention conidiation was comparable to wild type,Carolin Hof,2008,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2256,PHI:2049,UniProt,G4MW47,EMBL,ABY26907.1,,,70-15,SSM2,chromosome I,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,siderophore biosynthesis,,,,reduced virulence,,no,no,no,,reduced,,reduced,wild type,no,H2O2; KO2; FeSO4; FeCl3; ferric citrate,H2O2: CAS:7722-84-1; Ko2: CAS:12030-88-5; FeSO4: CAS:7720-78-7; FeCl3: CAS:7705-08-0; ferric citrate: CAS:2338-05-8,,,,,gene deletion: full; gene complementation,,,RP,19171198,PubMed,10.1016/j.fgb.2008.12.004,,"eisfeld@ibwf.de , katei@gmx.de",a siderophore independent uptake mechanism for ferrous and ferric iron exists in M. grisea.,Carolin Hof,2008,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2257,PHI:2050,UniProt,G4NF43,EMBL,BK005770.1,,,70-15,OMO1,chromosome IV,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,siderophore biosynthesis,,,,loss of pathogenicity,,,,,,reduced (absent),,reduced,wild type,no,H2O2; KO2; coprogen; FeSO4; FeCl3; ferric citrate; ferricrocin; ferrichrome,H2O2: CAS:7722-84-1; Ko2: CAS:12030-88-5; FeSO4: CAS:7720-78-7; FeCl3: CAS:7705-08-0; ferric citrate: CAS:2338-05-8; coprogen: CAS:31418-71-0; ferricrocin: CAS:23086-46-6; ferrichrome: CAS:15630-64-5,,,,,gene deletion: full; gene complementation,,,RP,19171198,PubMed,10.1016/j.fgb.2008.12.004,,"eisfeld@ibwf.de , katei@gmx.de",a siderophore independent uptake mechanism for ferrous and ferric iron exists in M. grisea. For pre-penetration defect 'no data found' as no conidiation; after complemention conidiation was comparable to wild type,Carolin Hof,2008,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2258,PHI:2051,UniProt,G4NGZ9,GenBank,MGG_03977.5,,,70-15,COS1,,,,,,,318829,Magnaporthe oryzae,,Y34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,root; leaf,transcriptional regulator,,,,increased virulence (hypervirulence),,yes,yes,no,,reduced (absent),,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19271955,PubMed,10.1094/MPMI-22-4-0402,,hecz@im.ac.cn,no comments,Zhuangzhi Zhou,2009,,19271955,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2259,PHI:2051,UniProt,G4NGZ9,GenBank,MGG_03977.5,,,70-15,COS1,,,,,,,318829,Magnaporthe oryzae,,Y34,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,root; leaf,transcriptional regulator,,,,increased virulence (hypervirulence),,yes,yes,no,,reduced (absent),,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19271955,PubMed,10.1094/MPMI-22-4-0402,,hecz@im.ac.cn,no comments,Zhuangzhi Zhou,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2260,PHI:2052,UniProt,G4NC11,GenBank,AF250928,,,70-15,Cdc42,,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sariceltik,,,seedling; leaf,actin cytoskeleton organization and cell polarity; establishment of turgor in appressoria,,,,reduced virulence,,yes,yes,yes,fewer and smaller disease lesions,reduced; aberrant,,wild type; aberrant,reduced; aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,19298860,PubMed,10.1016/j.fgb.2009.03.005,,"wusc@ccrc.uga.edu (S. Wu), zonghuaw@163.com",no comments,Wu Zheng,2009,,19298860,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2261,PHI:2052,UniProt,G4NC11,GenBank,AF250928,,,70-15,Cdc42,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sariceltik,,,seedling; leaf,actin cytoskeleton organization and cell polarity; establishment of turgor in appressoria,,,,reduced virulence,,yes,yes,yes,fewer and smaller disease lesions,reduced; aberrant,,wild type; aberrant,reduced; aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,19298860,PubMed,10.1016/j.fgb.2009.03.005,,"wusc@ccrc.uga.edu (S. Wu), zonghuaw@163.com",no comments,Wu Zheng,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2262,PHI:2052,UniProt,G4NC11,GenBank,AF250928,,,70-15,Cdc42,,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,actin cytoskeleton organization and cell polarity; establishment of turgor in appressoria,,,,reduced virulence,,yes,yes,yes,fewer and smaller disease lesions,reduced; aberrant,,wild type; aberrant,reduced; aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,19298860,PubMed,10.1016/j.fgb.2009.03.005,,"wusc@ccrc.uga.edu (S. Wu), zonghuaw@163.com",no comments,Wu Zheng,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2263,PHI:2052,UniProt,G4NC11,GenBank,AF250928,,,70-15,Cdc42,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,actin cytoskeleton organization and cell polarity; establishment of turgor in appressoria,,,,reduced virulence,,yes,yes,yes,fewer and smaller disease lesions,reduced; aberrant,,wild type; aberrant,reduced; aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,19298860,PubMed,10.1016/j.fgb.2009.03.005,,"wusc@ccrc.uga.edu (S. Wu), zonghuaw@163.com",no comments,Wu Zheng,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2264,PHI:2053,UniProt,G4NF05,GenBank,AB218802,,,70-15,Mstu1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,seedling; leaf,regulation of asexual fungal development,,,,loss of pathogenicity,no,yes,yes,no,,reduced,wild type,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19661696,PubMed,10.1271/bbb.90146,,marie@affrc.go.jp,no comments,Marie Nishimura,2009,,19661696,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2265,PHI:2053,UniProt,G4NF05,GenBank,AB218802,,,70-15,Mstu1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,seedling; leaf,regulation of asexual fungal development,,,,loss of pathogenicity,no,yes,yes,no,,reduced,wild type,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19661696,PubMed,10.1271/bbb.90146,,marie@affrc.go.jp,no comments,Marie Nishimura,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2266,PHI:2053,UniProt,G4NF05,GenBank,AB218802,,,70-15,Mstu1,,,,,,,318829,Magnaporthe oryzae,,3986-R45,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,seedling; leaf,regulation of asexual fungal development,,,,loss of pathogenicity,no,yes,yes,no,,reduced,wild type,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19661696,PubMed,10.1271/bbb.90146,,marie@affrc.go.jp,no comments,Marie Nishimura,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2267,PHI:2054,UniProt,G5EH19,GenBank,EF060241,,,70-15,Rac1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,actin cytoskeleton organization and polarized cell growth; conidiogenesis,,,MgRac1-Chm1 pathway,loss of pathogenicity,,yes,yes,,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,19008945,PubMed,10.1371/journal.ppat.1000202,,zonghuaw @163.com,no comments,Jisheng Chen,2008,,Chen_2008,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2268,PHI:2054,UniProt,G5EH19,GenBank,EF060241,,,70-15,Rac1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,actin cytoskeleton organization and polarized cell growth; conidiogenesis,,,MgRac1-Chm1 pathway,loss of pathogenicity,,yes,yes,,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,19008945,PubMed,10.1371/journal.ppat.1000202,,zonghuaw @163.com,no comments,Jisheng Chen,2008,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2269,PHI:2054,UniProt,G5EH19,GenBank,EF060241,,,70-15,Rac1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Jinchang 1316,,,leaf; root,actin cytoskeleton organization and polarized cell growth; conidiogenesis,,,MgRac1-Chm1 pathway,loss of pathogenicity,,yes,yes,,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,19008945,PubMed,10.1371/journal.ppat.1000202,,zonghuaw @163.com,no comments,Jisheng Chen,2008,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2270,PHI:2054,UniProt,G5EH19,GenBank,EF060241,,,70-15,Rac1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Jinchang 1316,,,leaf; root,actin cytoskeleton organization and polarized cell growth; conidiogenesis,,,MgRac1-Chm1 pathway,loss of pathogenicity,,yes,yes,,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,19008945,PubMed,10.1371/journal.ppat.1000202,,zonghuaw @163.com,no comments,Jisheng Chen,2008,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2271,PHI:2055,UniProt,Q1L5B8,GenBank,DQ028305,,,CgM2,PPT1,,,,,,,31870,Colletotrichum graminicola,,CgM2,anthracnose (maize),monocots,4577,Zea mays (related: maize),cv. Nathan,,,leaf,fungal pathogenicity factor,,,,loss of pathogenicity,,yes,yes,no,,reduced; aberrant,,reduced,wild type; aberrant,no,bathophenanthroline-disulfonate; desferri-ferrichrome; desferri-coprogen; H2O2; rose bengal,bathophenanthroline-disulfonate: CAS:52746-49-3; desferri-ferrichrome: CAS:34787-28-5; desferri-coprogen: CAS:31418-71-0; H2O2: CAS:7722-84-1; rose bengal: CAS:11121-48-5,,,,,gene deletion: full; gene complementation,,,RP,19880801,PubMed,10.1105/tpc.108.064188,,holger.deising@landw.uni-halle.de,no comments,Ralf Horbach,2009,,Horbach_2009,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2272,PHI:2056,,no data found,GenBank,MGG_03046,,,70-15,PPT1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,fungal pathogenicity factor,,,,loss of pathogenicity,,yes,yes,no,,reduced; aberrant,,reduced,wild type; aberrant,no,bathophenanthroline-disulfonate; desferri-ferrichrome; desferri-coprogen; H2O2; rose bengal,bathophenanthroline-disulfonate: CAS:52746-49-3; desferri-ferrichrome: CAS:34787-28-5; desferri-coprogen: CAS:31418-71-0; H2O2: CAS:7722-84-1; rose bengal: CAS:11121-48-5,,,,,gene deletion: full; gene complementation,,,RP,19880801,PubMed,10.1105/tpc.108.064188,,holger.deising@landw.uni-halle.de,no comments,Ralf Horbach,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2273,PHI:2057,UniProt,O93920,GenBank,AF098645,,,70-15,MoPLC1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf; seedling,modulator of calcium flux,,,calcium signalling,loss of pathogenicity,yes,yes,yes,yes,,reduced; aberrant,reduced; aberrant,reduced,reduced; aberrant,no,NaCl; calcium; DAG (diacylglycerol),,,,,,gene deletion: full; gene complementation,,,RP,19400837,PubMed,10.1111/J.1364-3703.2009.00536.X,,yonglee@snu.ac.kr,deltamoplc1 underwent lysis under hypertonic conditions. This suggests that MoPLC1-mediated calcium signalling is also involved in cellular processes that counteract osmotic stress in M. oryzae.,HEE-SOOL RHO,2009,,Rho_2009,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2274,PHI:2058,UniProt,A7U5U4,GenBank,ABS87374,,,70-15,LHS1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,seedling; leaf,endoplasmic reticulum chaperone,,,,reduced virulence,,no,yes,yes,smaller lesions with a white center surrounded by a dark-brown circle and yellowish margins.,reduced,,reduced,wild type,no,"Congo red; methyl violo-gen; hydrogen peroxide; 3-amino-1,2,4 triazole; calcium chloride; sodium chloride; p -coumaric acid; SDS; MnCl2; CuSO4","Congo red: CAS:573-58-0; methyl viologen: CAS:1910-42-5; hydrogen peroxide: CAS:7722-84-1; 3-amino-1,2,4 triazole: CAS:61-82-5; calcium chloride: CAS:10043-52-4; sodium chloride: CAS:7681-52-9; p -coumaric acid: CAS:501-98-4; MnCl2: CAS:7773-01-5; CuSO4: CAS:7758-99-7",,,,expression of the rice defense-related genes PR1a and PBZ1 in response to dlhs1 infection was less than that caused by infection with the wild-type KJ201 when analyzed by quantitative RT-PCR; reduced hypersensitive death,gene deletion: full; gene complementation,,,RP,19252083,PubMed,10.1105/tpc.107.055988,,yong lee@snu.ac.kr,"On CMA supplemented with Congo Red, methyl violo-gen, hydrogen peroxide, 3-amino-1,2,4 triazole, calcium chloride, sodium chloride, p -coumaric acid, and SDS, the growth rates of the mutant and the wild type were not significantly different from those on CMA. The growth rates of the mutant and the wild type in the presence of 10 mM MnCl 2 were similar to those of CMA. Although the growth rates of both the mutant and the wild type on CMA supplemented with 4 mM CuSO 4 were reduced relative to those on CMA, the degree of reduction in the mutant was more severe.",Mihwa Yi,2009,,Yi_2009,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2275,PHI:2058,UniProt,A7U5U4,GenBank,ABS87374,,,70-15,LHS1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Yashiro-mochi,,,seedling; leaf,endoplasmic reticulum chaperone,,,,reduced virulence,,no,yes,yes,smaller lesions with a white center surrounded by a dark-brown circle and yellowish margins.,reduced,,reduced,wild type,no,"Congo red; methyl violo-gen; hydrogen peroxide; 3-amino-1,2,4 triazole; calcium chloride; sodium chloride; p -coumaric acid; SDS; MnCl2; CuSO4","Congo red: CAS:573-58-0; methyl viologen: CAS:1910-42-5; hydrogen peroxide: CAS:7722-84-1; 3-amino-1,2,4 triazole: CAS:61-82-5; calcium chloride: CAS:10043-52-4; sodium chloride: CAS:7681-52-9; p -coumaric acid: CAS:501-98-4; MnCl2: CAS:7773-01-5; CuSO4: CAS:7758-99-7",,,,expression of the rice defense-related genes PR1a and PBZ1 in response to dlhs1 infection was less than that caused by infection with the wild-type KJ201 when analyzed by quantitative RT-PCR; reduced hypersensitive death,gene deletion: full; gene complementation,,,RP,19252083,PubMed,10.1105/tpc.107.055988,,yong lee@snu.ac.kr,"On CMA supplemented with Congo Red, methyl violo-gen, hydrogen peroxide, 3-amino-1,2,4 triazole, calcium chloride, sodium chloride, p -coumaric acid, and SDS, the growth rates of the mutant and the wild type were not significantly different from those on CMA. The growth rates of the mutant and the wild type in the presence of 10 mM MnCl 2 were similar to those of CMA. Although the growth rates of both the mutant and the wild type on CMA supplemented with 4 mM CuSO 4 were reduced relative to those on CMA, the degree of reduction in the mutant was more severe.",Mihwa Yi,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2276,PHI:2058,UniProt,A7U5U4,GenBank,ABS87374,,,70-15,LHS1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. YT16,,,seedling; leaf,endoplasmic reticulum chaperone,,,,reduced virulence,,no,yes,yes,smaller lesions with a white center surrounded by a dark-brown circle and yellowish margins.,reduced,,reduced,wild type,no,"Congo red; methyl violo-gen; hydrogen peroxide; 3-amino-1,2,4 triazole; calcium chloride; sodium chloride; p -coumaric acid; SDS; MnCl2; CuSO4","Congo red: CAS:573-58-0; methyl viologen: CAS:1910-42-5; hydrogen peroxide: CAS:7722-84-1; 3-amino-1,2,4 triazole: CAS:61-82-5; calcium chloride: CAS:10043-52-4; sodium chloride: CAS:7681-52-9; p -coumaric acid: CAS:501-98-4; MnCl2: CAS:7773-01-5; CuSO4: CAS:7758-99-7",,,,expression of the rice defense-related genes PR1a and PBZ1 in response to dlhs1 infection was less than that caused by infection with the wild-type KJ201 when analyzed by quantitative RT-PCR; reduced hypersensitive death,gene deletion: full; gene complementation,,,RP,19252083,PubMed,10.1105/tpc.107.055988,,yong lee@snu.ac.kr,"On CMA supplemented with Congo Red, methyl violo-gen, hydrogen peroxide, 3-amino-1,2,4 triazole, calcium chloride, sodium chloride, p -coumaric acid, and SDS, the growth rates of the mutant and the wild type were not significantly different from those on CMA. The growth rates of the mutant and the wild type in the presence of 10 mM MnCl 2 were similar to those of CMA. Although the growth rates of both the mutant and the wild type on CMA supplemented with 4 mM CuSO 4 were reduced relative to those on CMA, the degree of reduction in the mutant was more severe.",Mihwa Yi,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2277,PHI:2059,UniProt,G4N4P0,GenBank,XM_359644.1,,,70-15,MgCRZ1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,transcription factor,,,calcineurin dependent signaling pathway,reduced virulence,,,yes,yes,small and isolated lesions,reduced,,,,no,Ca+,calcium: CAS:7440-70-2,,,,,gene deletion: partial; gene complementation,,,RP,19260966,PubMed,10.1111/j.1574-6968.2009.01524.x,,zhgzhang@njau.edu.cn,"crz1 mutants showed a higher sensitivity to Ca (0 .2-0. 6 M) than did the wild-type strain. However, the mutants did not alter their responses to other stress conditions (Na ,Li ,and Mn) or to oxidative stress. These results re ve aled that MgC RZ1 is required for Ca21 stress tolerance in M. grisea",Haifeng Zhang,2009,,Zhang_2009,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2278,PHI:2059,UniProt,G4N4P0,GenBank,XM_359644.1,,,70-15,MgCRZ1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Four-arris,,,seedling; leaf,transcription factor,,,calcineurin dependent signaling pathway,reduced virulence,,,yes,yes,small and isolated lesions,reduced,,,,no,Ca+,calcium: CAS:7440-70-2,,,,,gene deletion: partial; gene complementation,,,RP,19260966,PubMed,10.1111/j.1574-6968.2009.01524.x,,zhgzhang@njau.edu.cn,"crz1 mutants showed a higher sensitivity to Ca (0 .2-0. 6 M) than did the wild-type strain. However, the mutants did not alter their responses to other stress conditions (Na ,Li ,and Mn) or to oxidative stress. These results re ve aled that MgC RZ1 is required for Ca21 stress tolerance in M. grisea",Haifeng Zhang,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2279,PHI:2060,UniProt,G4N5E4,EMBL,AB353135,,,70-15,MgLig4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,DNA ligase; non-homologous end-joining events,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,wild type,,camptothecin; methyl methanesulfonate; bleomycin; 4-nitroquinoline 1-oxidase; hydroxyurea; ethyl methanesulfonate; UV irradiation,camptothecin: CAS:7689-03-4; methyl methanesulfonate: CAS:66-27-3; bleomycin: CAS:11056-06-7; hydroxyurea: CAS:127-07-1; ethyl methanesulfonate: CAS:62-50-0,,,,,gene deletion: full; gene complementation,,,AR,18854221,PubMed,10.1016/j.fgb.2008.09.005,,marie@affrc.go.jp,"Mglig4 mutants were slightly more sensitive to camptothecin than Guy11. Their sensitivity to the other DNA-damaging agents (MMS, bleo-mycin, 4NQO, HU, EMS, UV irradiation) was comparable to that of the wild-type (data not shown). Re-introducing the wild-type MgLIG4 gene into mglig4 suppressed its sensitivity to camptothecin.",Hideki Kito,2008,,18854221,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2280,PHI:2060,UniProt,G4N5E4,EMBL,AB353135,,,70-15,MgLig4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),P2,,,,DNA ligase; non-homologous end-joining events,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,,camptothecin; methyl methanesulfonate; bleomycin; 4-nitroquinoline 1-oxidase; hydroxyurea; ethyl methanesulfonate; UV irradiation,camptothecin: CAS:7689-03-4; methyl methanesulfonate: CAS:66-27-3; bleomycin: CAS:11056-06-7; hydroxyurea: CAS:127-07-1; ethyl methanesulfonate: CAS:62-50-0,,,,,gene deletion: full; gene complementation,,,AR,18854221,PubMed,10.1016/j.fgb.2008.09.005,,marie@affrc.go.jp,"Mglig4 mutants were slightly more sensitive to camptothecin than Guy11. Their sensitivity to the other DNA-damaging agents (MMS, bleo-mycin, 4NQO, HU, EMS, UV irradiation) was comparable to that of the wild-type (data not shown). Re-introducing the wild-type MgLIG4 gene into mglig4 suppressed its sensitivity to camptothecin.",Hideki Kito,2008,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2281,PHI:2061,UniProt,Q51MW4,GenBank,XP_368182,,,70-15,ATG8,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,,,,,loss of pathogenicity,,,yes,,,reduced; defective; aberrant,,reduced; aberrant,,,glucose; sucrose; glucose-6-phosphate; glucose-1-phosphate,glucose: CAS:50-99-7; sucrose: CAS:57-50-1; glucose-6-phosphate: CAS:56-73-5; glucose-1-phosphate: CAS:59-56-3,,,,,gene deletion: full; gene complementation,,,AR,19115483,PubMed,no data found,,naweed@tll.org.sg,"atg8delta gained a fluffy appearance, suggesting restoration of aerial hyphal growth, when supplemented with glucose or sucrose as a carbon source. Interestingly, the addition of sucrose or glucose significantly restored conidiation in atg8delta even in the presence of the nonrepressible disaccharide, lactose (p = 0.001; Fig. 3A). Although profuse (Fig. 3B) the suppression of atg8delta conidi-ation was lower in glucose (about 64 x 102 conidia/cm2; Fig. 3A) when compared to that induced by sucrose; Glucose-6-phosphate caused a remarkable suppression of conidiation defects. However, exogenous Glucose-1-phosphate was unable to suppress the conidiation defects",Yi Zhen Deng,2009,,19115483,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2282,PHI:2062,UniProt,G4MW66,GenBank,XP_363893,,,70-15,Gph1,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,,,,,unaffected pathogenicity,,,no,no,,wild type,,wild type,,,,,,,,,gene deletion: full,,,AR,19115483,PubMed,no data found,,naweed@tll.org.sg,no comments,Yi Zhen Deng,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2283,PHI:2061,UniProt,Q51MW4,GenBank,XP_368182,,,70-15,ATG8,,,,,,PHI:2062,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,,,,,loss of pathogenicity,,,yes,yes,,reduced; defective,,reduced; aberrant,,,,,,,,slight induction of hypersensitive reaction,gene deletion: full,,,AR,19115483,PubMed,no data found,,naweed@tll.org.sg,no comments,Yi Zhen Deng,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2284,PHI:2062,UniProt,G4MW66,GenBank,XP_363893,,,70-15,Gph1,,,,,,PHI:2061,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,,,,,loss of pathogenicity,,,yes,yes,,reduced; defective,,reduced; aberrant,,,,,,,,slight induction of hypersensitive reaction,gene deletion: full,,,AR,19115483,PubMed,no data found,,naweed@tll.org.sg,no comments,Yi Zhen Deng,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2285,PHI:2063,UniProt,G4N168,Broad,MGG_07456.6,,,70-15,MCNA,,transformant 3B containing the antisense construct of MCNA,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,,,,,reduced virulence,,yes,,,diamond-shaped and gray-centered lesions,reduced,,reduced; aberrant,wild type,,calcium chloride; cyclic AMP,calcium chloride: CAS:10035-04-8; cyclic AMP: CAS:60-92-4,,,,fewer and smaller lesions,altered gene expression / gene regulation: silencing,,,AR,19190403,PubMed,10.4014/jmb.0804.268,,yonglee@snu.ac.kr,Addition of exogenous CaCl2 or cAMP restored appressorium formation,Choi,2009,,19190403,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2286,PHI:2063,UniProt,G4N168,Broad,MGG_07456.6,,,70-15,MCNA,,transformant S53B containing the sense construct of MCNA,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,,,,,reduced virulence,,yes,,,diamond-shaped and gray-centered lesions,reduced,,reduced; aberrant,wild type,,calcium chloride; cyclic AMP,calcium chloride: CAS:10035-04-8; cyclic AMP: CAS:60-92-4,,,,fewer and smaller lesions,altered gene expression / gene regulation: silencing,,,AR,19190403,PubMed,10.4014/jmb.0804.268,,yonglee@snu.ac.kr,Addition of exogenous CaCl2 or cAMP restored appressorium formation,Choi,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2287,PHI:2064,UniProt,C6ZEZ6,,,,,81278ZB15,AvrPiz-t,chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,functional test in host,,,AR,19271956,PubMed,10.1094/MPMI-22-4-0411,,bzhou@ncgr.ac.cn,no comments,Wei Li,2009,,19271956,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2288,PHI:2065,UniProt,Q4R1B9,Broad,MGG_00692.6,,,70-15,MSTU1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,mobilization of lipids and glycogen,,,,loss of pathogenicity,,,yes,no,,reduced,wild type,reduced,wild type,,,,,,,,gene deletion: full; gene complementation,,,AR,19337737,PubMed,10.1271/bbb.90146,,marie@affrc.go.jp,no comments,Marie Nishimura,2009,,19337737,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2289,PHI:2065,UniProt,Q4R1B9,Broad,MGG_00692.6,,,70-15,MSTU1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,mobilization of lipids and glycogen,,,,loss of pathogenicity,,,,,,reduced,,reduced,wild type,,,,,,,,gene deletion: full,,,AR,19337737,PubMed,10.1271/bbb.90146,,marie@affrc.go.jp,no comments,Marie Nishimura,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2290,PHI:2065,UniProt,Q4R1B9,Broad,MGG_00692.6,,,70-15,MSTU1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,mobilization of lipids and glycogen,,,,loss of pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,AR,19337737,PubMed,10.1271/bbb.90146,,marie@affrc.go.jp,no comments,Marie Nishimura,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2291,PHI:2066,UniProt,Q51WZ9,Broad,MGG_09559.5,,,70-15,MgAtg9,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,,,,,,reduced,,,,,,,,,gene deletion: full; gene complementation,,,AR,19556868,PubMed,no data found,,fuchenglin@zju.edu.cn,no comments,Bo Dong,2009,,19556868,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2292,PHI:2067,UniProt,G4NDE1,GenBank,MGG_00937.5,,,70-15,ABC4,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,multidrug resistance,,,,loss of pathogenicity,,yes,yes,yes,,,,reduced,,,resveratrol; miconazole; cycloheximide; camptothecin; methotrexate,resveratrol: CAS:501-36-0; miconazole: CAS:22916-47-8; cycloheximide: CAS:66-81-9; camptothecin: CAS:7689-03-4; methotrexate: CAS:59-05-2,,,,,other evidence: insertional mutagenesis screen,,,AR,18034832,PubMed,10.1111/j.1574-6968.2007.00937.x,,bharat.chattoo@bcmsu.ac.in,"The mutant abc4 showed increased sensitivity to resveratrol, miconazole and cycloheximide, whereas the difference in growth was not significant in case of camptothecin and methotrexate.",Archna Gupta,2008,,Gupta-2008-Functional analysis,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2293,PHI:2068,UniProt,G4NIP2,GenBank,XP_361689,,,70-15,DES1,chromosome IV,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,regulation of ferrous ions,,,,reduced virulence,,no,,yes,brown granule generation and cell death,aberrant,,wild type,wild type,,diphenyleneiodonium,diphenyleneiodonium: CAS:244-54-2,,,,,gene deletion: full; gene complementation,,,AR,19390617,PubMed,10.1371/journal.ppat.1000401,,yonglee@snu.ac.kr,"the attenuated virulence phenotypes of des1 deletion mutant and DES1 T-DN A mutant were rescued in the rice sheath cells in which ROS generation was inhibited by DPI. Treatment with DPI completely prevented the production of brown granules, and both mutants could develop IH.",Myoung-Hwan Chi,2009,,Chi-2009-A novel pathogenicit,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2294,PHI:2068,UniProt,G4NIP2,GenBank,XP_361689,,,70-15,DES1,chromosome IV,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,regulation of ferrous ions,,,,reduced virulence,,no,,yes,,aberrant,,increased,wild type,,diphenyleneiodonium,diphenyleneiodonium: CAS:244-54-2,,,,,other evidence: insertional mutagenesis screen,,,AR,19390617,PubMed,10.1371/journal.ppat.1000401,,yonglee@snu.ac.kr,"the attenuated virulence phenotypes of des1 deletion mutant and DES1 T-DN A mutant were rescued in the rice sheath cells in which ROS generation was inhibited by DPI. Treatment with DPI completely prevented the production of brown granules, and both mutants could develop IH.",Myoung-Hwan Chi,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2295,PHI:2068,UniProt,G4NIP2,GenBank,XP_361689,,,70-15,DES1,chromosome IV,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4679,Allium cepa (related: onion),,,,plant epidermis,regulation of ferrous ions,,,,reduced virulence,,,no,yes,,,,,,,diphenyleneiodonium,diphenyleneiodonium: CAS:244-54-2,,,,callose deposition,gene deletion: full; gene complementation,,,AR,19390617,PubMed,10.1371/journal.ppat.1000401,,yonglee@snu.ac.kr,"Treatment of DPI recovered the frequencies of IH development by des1 deletion mutant and DES1 T-DNA mutant up to 28% and 21%, respectively.",Myoung-Hwan Chi,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2296,PHI:2068,UniProt,G4NIP2,GenBank,XP_361689,,,70-15,DES1,chromosome IV,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4679,Allium cepa (related: onion),,,,plant epidermis,regulation of ferrous ions,,,,reduced virulence,,,no,yes,,,,,,,diphenyleneiodonium,diphenyleneiodonium: CAS:244-54-2,,,,callose deposition,other evidence: insertional mutagenesis screen,,,AR,19390617,PubMed,10.1371/journal.ppat.1000401,,yonglee@snu.ac.kr,"Treatment of DPI recovered the frequencies of IH development by des1 deletion mutant and DES1 T-DNA mutant up to 28% and 21%, respectively.",Myoung-Hwan Chi,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2297,PHI:2069,UniProt,Q52EB3,GenBank,MGG_06393.6,,,70-15,Moatg1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,Kershaw-2009-Genome-wide function,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2298,PHI:2070,UniProt,Q51ZN8,GenBank,MGG_05998.6,,,70-15,Moatg2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2299,PHI:2071,UniProt,Q51LD2,GenBank,MGG_02959.6,,,70-15,Moatg3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2300,PHI:2072,UniProt,Q523C3,GenBank,MGG_03580.6,,,70-15,Moatg4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full; gene complementation,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2301,PHI:2073,UniProt,Q525E4,GenBank,MGG_09262.6,,,70-15,Moatg5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2302,PHI:2074,UniProt,G4N6Q1,GenBank,MGG_03694.6,,,70-15,Moatg6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2303,PHI:2075,UniProt,Q52CS0,GenBank,MGG_07297.6,,,70-15,Moatg7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2304,PHI:2076,UniProt,Q51MW4,GenBank,MGG_01062.6,,,70-15,Moatg8,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full; gene complementation,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2305,PHI:2077,UniProt,Q51WZ9,GenBank,MGG_09559.6,,,70-15,Moatg9,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full; gene complementation,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2306,PHI:2078,UniProt,G4MYZ2,GenBank,MGG_14737.6,,,70-15,Moatg10,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2307,PHI:2079,UniProt,Q51P78,GenBank,MGG_00598.6,,,70-15,Moatg12,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full; gene complementation,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2308,PHI:2080,UniProt,G4NC26,GenBank,MGG_00454.6,,,70-15,Moatg13,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,reduced virulence,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2309,PHI:2081,UniProt,G4N703,GenBank,MGG_12828.6,,,70-15,Moatg15,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2310,PHI:2082,UniProt,Q520U5,GenBank,MGG_05255.6,,,70-15,Moatg16,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2311,PHI:2083,UniProt,Q51Y68,GenBank,MGG_07667.6,,,70-15,Moatg17,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2312,PHI:2084,UniProt,Q524W4,GenBank,MGG_03139.6,,,70-15,Moatg18,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,reduced virulence,,yes,yes,yes,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2313,PHI:2085,UniProt,Q51UJ9,GenBank,MGG_04486.6,,,70-15,Moatg11,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2314,PHI:2086,UniProt,Q522W5,GenBank,MGG_03638.6,,,70-15,Moatg24,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2315,PHI:2087,UniProt,G4N8A1,GenBank,MGG_03459.6,,,70-15,Moatg26,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2316,PHI:2088,UniProt,G4MR15,GenBank,MGG_02386.6,,,70-15,Moatg27,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2317,PHI:2089,UniProt,G4MXR9,GenBank,MGG_08061.6,,,70-15,Moatg28,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2318,PHI:2090,UniProt,G4NIZ2,GenBank,MGG_02790.6,,,70-15,Moatg29,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,AR,19717456,PubMed,10.1073/pnas.0901477106,,n.j.talbot@exeter.ac.uk,no comments,Michael J. Kershaw,2009,,,Batch003a,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2319,PHI:2091,UniProt,Q525E4,GenBank,EF486491,,,70-15,MgATG5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,,,,minor brown single lesion,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,AR,19629489,PubMed,10.1007/s00294-009-0259-5,,fuchenglin@zju.edu.cn,no comments,Jian-Ping Lu,2009,,Lu_CurGen2009_MoATG5,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2320,PHI:2091,UniProt,Q525E4,GenBank,EF486491,,,70-15,MgATG5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. ZJ-8,,,leaf,,,,,loss of pathogenicity,,,yes,no,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,AR,19629489,PubMed,10.1007/s00294-009-0259-5,,fuchenglin@zju.edu.cn,no comments,Jian-Ping Lu,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2321,PHI:2092,UniProt,G4MNL6,GenBank,MGG_05643.5,,,70-15,Cch1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+-permeable channel,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,Nguyen-2008-Systematic functiona,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2322,PHI:2092,UniProt,G4MNL6,GenBank,MGG_05643.5,,,70-15,Cch1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+-permeable channel,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2323,PHI:2092,UniProt,G4MNL6,GenBank,MGG_05643.5,,,70-15,Cch1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+-permeable channel,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2324,PHI:2093,UniProt,G4NGX3,GenBank,MGG_12128.5,,,70-15,Mid1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+-permeable channel,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2325,PHI:2093,UniProt,G4NGX3,GenBank,MGG_12128.5,,,70-15,Mid1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+-permeable channel,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2326,PHI:2093,UniProt,G4NGX3,GenBank,MGG_12128.5,,,70-15,Mid1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+-permeable channel,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2327,PHI:2094,UniProt,G4NII5,GenBank,MGG_09828.5,,,70-15,Yvc1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+-permeable channel,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2328,PHI:2094,UniProt,G4NII5,GenBank,MGG_09828.5,,,70-15,Yvc1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+-permeable channel,,,,loss of pathogenicity,,yes,,,,reduced; aberrant,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2329,PHI:2094,UniProt,G4NII5,GenBank,MGG_09828.5,,,70-15,Yvc1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+-permeable channel,,,,loss of pathogenicity,,yes,,,,reduced; aberrant,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2330,PHI:2095,UniProt,G4MXG4,GenBank,MGG_10730.5,,,70-15,Calcium-transporting ATPase 3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ pump,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2331,PHI:2095,UniProt,G4MXG4,GenBank,MGG_10730.5,,,70-15,Calcium-transporting ATPase 3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ pump,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2332,PHI:2095,UniProt,G4MXG4,GenBank,MGG_10730.5,,,70-15,Calcium-transporting ATPase 3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ pump,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2333,PHI:2096,UniProt,G4MNA5,GenBank,MGG_02074.5,,,70-15,Calcium-transporting ATPase 3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2334,PHI:2096,UniProt,G4MNA5,GenBank,MGG_02074.5,,,70-15,Calcium-transporting ATPase 3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2335,PHI:2096,UniProt,G4MNA5,GenBank,MGG_02074.5,,,70-15,Calcium-transporting ATPase 3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2336,PHI:2097,UniProt,G4NGP6,GenBank,MGG_04066.5,,,70-15,Neo1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2337,PHI:2097,UniProt,G4NGP6,GenBank,MGG_04066.5,,,70-15,Neo1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2338,PHI:2097,UniProt,G4NGP6,GenBank,MGG_04066.5,,,70-15,Neo1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2339,PHI:2098,UniProt,G4N471,GenBank,MGG_05078.5,,,70-15,Calcium-transporting ATPase 3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2340,PHI:2098,UniProt,G4N471,GenBank,MGG_05078.5,,,70-15,Calcium-transporting ATPase 3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2341,PHI:2098,UniProt,G4N471,GenBank,MGG_05078.5,,,70-15,Calcium-transporting ATPase 3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2342,PHI:2099,UniProt,G4N2W2,GenBank,MGG_07971.5,,,70-15,Pmc1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ pump,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2343,PHI:2099,UniProt,G4N2W2,GenBank,MGG_07971.5,,,70-15,Pmc1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced; aberrant,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2344,PHI:2099,UniProt,G4N2W2,GenBank,MGG_07971.5,,,70-15,Pmc1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced; aberrant,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2345,PHI:2100,UniProt,G4NI28,GenBank,MGG_12005.5,,,70-15,Spf1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ pump,,,,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2346,PHI:2100,UniProt,G4NI28,GenBank,MGG_12005.5,,,70-15,Spf1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2347,PHI:2100,UniProt,G4NI28,GenBank,MGG_12005.5,,,70-15,Spf1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ pump,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2348,PHI:2101,UniProt,G4NCW8,GenBank,MGG_11454.5,,,70-15,MGG_11454.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2349,PHI:2101,UniProt,G4NCW8,GenBank,MGG_11454.5,,,70-15,MGG_11454.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2350,PHI:2101,UniProt,G4NCW8,GenBank,MGG_11454.5,,,70-15,MGG_11454.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2351,PHI:2102,,no data found,GenBank,MGG_01193.5,,,70-15,MGG_01193.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2352,PHI:2102,,no data found,GenBank,MGG_01193.5,,,70-15,MGG_01193.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ exchanger,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2353,PHI:2102,,no data found,GenBank,MGG_01193.5,,,70-15,MGG_01193.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ exchanger,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2354,PHI:2103,UniProt,G4NFU3,GenBank,MGG_08710.5,,,70-15,MGG_08710.5,,,,,,PHI:2104,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,"Due to high sequence similarity between MGG08710.5 and MGG04159.5, the genes were silenced simultaneously (Table 2). Therefore, the phenotypes of mgg08710.5 and mgg04159.5 knock-down mutants resulted from silencing of both, but not one, of the genes.",Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2355,PHI:2103,UniProt,G4NFU3,GenBank,MGG_08710.5,,,70-15,MGG_08710.5,,,,,,PHI:2104,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,"Due to high sequence similarity between MGG08710.5 and MGG04159.5, the genes were silenced simultaneously (Table 2). Therefore, the phenotypes of mgg08710.5 and mgg04159.5 knock-down mutants resulted from silencing of both, but not one, of the genes.",Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2356,PHI:2103,UniProt,G4NFU3,GenBank,MGG_08710.5,,,70-15,MGG_08710.5,,,,,,PHI:2104,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,"Due to high sequence similarity between MGG08710.5 and MGG04159.5, the genes were silenced simultaneously (Table 2). Therefore, the phenotypes of mgg08710.5 and mgg04159.5 knock-down mutants resulted from silencing of both, but not one, of the genes.",Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2357,PHI:2104,UniProt,G4NIP8,GenBank,MGG_04159.5,,,70-15,MGG_04159.5,,,,,,PHI:2103,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,"Due to high sequence similarity between MGG08710.5 and MGG04159.5, the genes were silenced simultaneously (Table 2). Therefore, the phenotypes of mgg08710.5 and mgg04159.5 knock-down mutants resulted from silencing of both, but not one, of the genes.",Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2358,PHI:2104,UniProt,G4NIP8,GenBank,MGG_04159.5,,,70-15,MGG_04159.5,,,,,,PHI:2103,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,"Due to high sequence similarity between MGG08710.5 and MGG04159.5, the genes were silenced simultaneously (Table 2). Therefore, the phenotypes of mgg08710.5 and mgg04159.5 knock-down mutants resulted from silencing of both, but not one, of the genes.",Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2359,PHI:2104,UniProt,G4NIP8,GenBank,MGG_04159.5,,,70-15,MGG_04159.5,,,,,,PHI:2103,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,"Due to high sequence similarity between MGG08710.5 and MGG04159.5, the genes were silenced simultaneously (Table 2). Therefore, the phenotypes of mgg08710.5 and mgg04159.5 knock-down mutants resulted from silencing of both, but not one, of the genes.",Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2360,PHI:2105,UniProt,G4MZ47,GenBank,MGG_01381.5,,,70-15,Calcium permease,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2361,PHI:2105,UniProt,G4MZ47,GenBank,MGG_01381.5,,,70-15,Calcium permease,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+ exchanger,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2362,PHI:2105,UniProt,G4MZ47,GenBank,MGG_01381.5,,,70-15,Calcium permease,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+ exchanger,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2363,PHI:2106,UniProt,G4N054,GenBank,MGG_05332.5,,,70-15,MGG_05332.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,phospholipase C,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2364,PHI:2106,UniProt,G4N054,GenBank,MGG_05332.5,,,70-15,MGG_05332.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,phospholipase C,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2365,PHI:2106,UniProt,G4N054,GenBank,MGG_05332.5,,,70-15,MGG_05332.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,phospholipase C,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2366,PHI:2107,UniProt,G4N402,GenBank,MGG_05905.5,,,70-15,MGG_05905.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,phospholipase C,,,,unaffected pathogenicity,,yes,,,,reduced; aberrant,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2367,PHI:2107,UniProt,G4N402,GenBank,MGG_05905.5,,,70-15,MGG_05905.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,phospholipase C,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2368,PHI:2107,UniProt,G4N402,GenBank,MGG_05905.5,,,70-15,MGG_05905.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,phospholipase C,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2369,PHI:2108,UniProt,Q9UWF0,GenBank,MGG_06884.5,,,70-15,CAM,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2370,PHI:2108,UniProt,Q9UWF0,GenBank,MGG_06884.5,,,70-15,CAM,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2371,PHI:2108,UniProt,Q9UWF0,GenBank,MGG_06884.5,,,70-15,CAM,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2372,PHI:2109,UniProt,G4MNE6,GenBank,MGG_06933.5,,,70-15,CNB,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2373,PHI:2109,UniProt,G4MNE6,GenBank,MGG_06933.5,,,70-15,CNB,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2374,PHI:2109,UniProt,G4MNE6,GenBank,MGG_06933.5,,,70-15,CNB,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2375,PHI:2110,UniProt,G4N168,GenBank,MGG_07456.5,,,70-15,MGG_07456.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,serine/threonine-protein phosphatase 2B catalytic subunit,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2376,PHI:2110,UniProt,G4N168,GenBank,MGG_07456.5,,,70-15,MGG_07456.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,serine/threonine-protein phosphatase 2B catalytic subunit,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2377,PHI:2110,UniProt,G4N168,GenBank,MGG_07456.5,,,70-15,MGG_07456.5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,serine/threonine-protein phosphatase 2B catalytic subunit,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2378,PHI:2111,,no data found,GenBank,MGG_00925.5,,,70-15,Cmk1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+/CAM-dependent serine/threonine protein kinases,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2379,PHI:2111,,no data found,GenBank,MGG_00925.5,,,70-15,Cmk1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+/CAM-dependent serine/threonine protein kinases,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2380,PHI:2111,,no data found,GenBank,MGG_00925.5,,,70-15,Cmk1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+/CAM-dependent serine/threonine protein kinases,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2381,PHI:2112,UniProt,G4N7H1,GenBank,MGG_06421.5,,,70-15,Tos3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+/CAM-dependent serine/threonine protein kinases,,,,unaffected pathogenicity,,no,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2382,PHI:2112,UniProt,G4N7H1,GenBank,MGG_06421.5,,,70-15,Tos3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+/CAM-dependent serine/threonine protein kinases,,,,unaffected pathogenicity,,no,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2383,PHI:2112,UniProt,G4N7H1,GenBank,MGG_06421.5,,,70-15,Tos3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+/CAM-dependent serine/threonine protein kinases,,,,unaffected pathogenicity,,no,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2384,PHI:2113,UniProt,G4MWY5,GenBank,MGG_01196.5,,,70-15,Kin4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,Ca2+/CAM-dependent serine/threonine protein kinases,,,,reduced virulence,,yes,,,,increased,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2385,PHI:2113,UniProt,G4MWY5,GenBank,MGG_01196.5,,,70-15,Kin4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,Ca2+/CAM-dependent serine/threonine protein kinases,,,,loss of pathogenicity,,yes,,,,increased,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2386,PHI:2113,UniProt,G4MWY5,GenBank,MGG_01196.5,,,70-15,Kin4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,Ca2+/CAM-dependent serine/threonine protein kinases,,,,loss of pathogenicity,,yes,,,,increased,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2387,PHI:2114,UniProt,G4MTZ0,GenBank,MGG_01607.5,,,70-15,Calnexin,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2388,PHI:2114,UniProt,G4MTZ0,GenBank,MGG_01607.5,,,70-15,Calnexin,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2389,PHI:2114,UniProt,G4MTZ0,GenBank,MGG_01607.5,,,70-15,Calnexin,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2390,PHI:2115,UniProt,G4MMH7,GenBank,MGG_06847.5,,,70-15,Annexin A7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2391,PHI:2115,UniProt,G4MMH7,GenBank,MGG_06847.5,,,70-15,Annexin A7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2392,PHI:2115,UniProt,G4MMH7,GenBank,MGG_06847.5,,,70-15,Annexin A7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,AR,18433453,PubMed,10.1111/j.1365-2958.2008.06242.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2008,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2393,PHI:2116,UniProt,B5M4A8,GenBank,EU935590,,,70-15,CHS7,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,reduced virulence,,yes,yes,no,,wild type,,wild type,wild type,no,"1,16-hexadecanediol; 1,2-dioctanoylglycerol; 8-((4-chlorophenyl)thio)cyclic-3',5'-amp","1,16-hexadecanediol: CAS:7735-42-4; 1,2-dioctanoylglycerol: CAS:1069-87-0; 8-((4-chlorophenyl)thio)cyclic-3',5'-amp: CAS:41941-66-6",,,,,gene deletion: full; gene complementation,,,AR,19161355,PubMed,10.1111/J.1364-3703.2008.00515.X,,foster@ibwf.de,"In stark contrast with WT, the chs7null mutant formed no appressoria in response to an artificial hydrophobic surface. Appressorium formation on these surfaces could be restored by application of the cutin monomer 1,16-hexadecanediol (1,16-HDD), the diacylglycerol 1,2-dioctanoyl-rac-glycerol (DOG) or 8-(4-chlorophenylthio)-cyclic adenosine monophosphate (8-CPT-cAMP)",Dominik Odenbach,2009,,Odenbach-2009-The Magnaporthe gris,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2394,PHI:2117,UniProt,P58371,GenBank,MGG_03670.6,,,70-15,SPM1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Shin 2,,,leaf,protease activity,,,endocytotic pathway,reduced virulence,,yes,,yes,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,AR,19765082,PubMed,10.1111/j.1574-6968.2009.01769.x,,ytakano@kais.kyoto-u.ac.jp,no comments,Hiromas a Saitoh,2009,,Saitoh-2009-SPM1 encoding a vacu,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2395,PHI:2117,UniProt,P58371,GenBank,MGG_03670.6,,,70-15,SPM1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nigrate,,,leaf,protease activity,,,endocytotic pathway,reduced virulence,,yes,,,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,AR,19765082,PubMed,10.1111/j.1574-6968.2009.01769.x,,ytakano@kais.kyoto-u.ac.jp,no comments,Hiromas a Saitoh,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2396,PHI:2118,UniProt,G4MKI0,GenBank,MGG_05344.6,,,70-15,MgSM1,,,,,,,318829,Magnaporthe oryzae,,85-14B1,blast (rice),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,"hypersensitive response with generation of water soaked lesions around infiltration site which further enlarged and further enlarged and collapsed large areas of tissues around infiltration sites; confers disease resistance (small necrotic lesions , few and small chlorotic lesions) against different fungal and bacterial pathogens including B. cinerea, P. syringae pv. tomato and A. brassicicola.",functional test in host: transient expression,,,AR,19754836,PubMed,10.1111/j.1467-7652.2009.00442.x,,fmsong@zju.edu.cn,Transient expression of MgSM1 in lower leaves confer enhanced disease resistance in the upper parts of the Arabidopsis plants; MgSM1 does not have significant toxic effect on plants but its higher levels could have hal effects,Yayun Yang,2009,,Yang-2009-Ectopic expression o,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2397,PHI:2119,UniProt,G4N7X0,GenBank,MGG_14847.6,,,70-15,MST11p,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,MAPK signalling,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,no comments,Bastian Kramer,2009,,19520179,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2398,PHI:2120,UniProt,G4NEB8,GenBank,MGG_00800.6,,,70-15,MST7p,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,MAPK signalling,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,no comments,Bastian Kramer,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2399,PHI:2121,UniProt,G4N525,GenBank,MGG_05199.6,,,70-15,MST50p,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,MAPK signalling,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,no comments,Bastian Kramer,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2400,PHI:2122,UniProt,G4N3L5,GenBank,MGG_12958.6,,,70-15,MST12p,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,MAPK signalling,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,no comments,Bastian Kramer,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2401,PHI:2123,UniProt,C6KEF4,EMBL,GQ183953,,,IPO323,MGSTE11p,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,leaf blotch,monocots,4564,Triticum (related: wheat),cv. Riband,,,leaf,,,,MAPK signalling,loss of pathogenicity,,,yes,yes,,,,reduced; aberrant,,no,strobilurin A; sordarin; NaCl; sorbitol; H2O2; SDS; resorcinol,strobilurin A: CAS:52110-55-1; sordarin: CAS:11076-17-8; NaCl: CAS:7647-14-5; sorbitol: CAS:50-70-4; ;H2O2: CAS:7722-84-1; ;resorcinol: CAS:108-46-3,,,,,gene deletion: full; gene complementation,,,RP,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,"The deletion mutant did not exhibit any change in sensitivity/resistance to a range of different chemicals and stresses like exposure to the fungicides (strobilurin A, sordarin), salt stress (0.2 - 1.2 M NaCl), hypo- and hyperosmotic stress (range of concentrations of sorbitol up to 1.8 M), oxidative stress (5 - 100 mM H 2 O2), SDS (1 lM - 1 mM) and exposure to the wheat plant defence compound Resorcinol.",Bastian Kramer,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2402,PHI:2124,UniProt,C5MK57,EMBL,GQ119346,,,IPO323,MGSTE7p,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,leaf blotch,monocots,4564,Triticum (related: wheat),cv. Riband,,,leaf,,,,MAPK signalling,loss of pathogenicity,,,yes,yes,,,,reduced; aberrant,,no,strobilurin A; sordarin; NaCl; sorbitol; H2O2; SDS; resorcinol,strobilurin A: CAS:52110-55-1; sordarin: CAS:11076-17-8; NaCl: CAS:7647-14-5; sorbitol: CAS:50-70-4; ;H2O2: CAS:7722-84-1; ;resorcinol: CAS:108-46-3,,,,,gene deletion: full; gene complementation,,,RP,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,"The deletion mutant did not exhibit any change in sensitivity/resistance to a range of different chemicals and stresses like exposure to the fungicides (strobilurin A, sordarin), salt stress (0.2 - 1.2 M NaCl), hypo- and hyperosmotic stress (range of concentrations of sorbitol up to 1.8 M), oxidative stress (5 - 100 mM H 2 O2), SDS (1 lM - 1 mM) and exposure to the wheat plant defence compound Resorcinol.",Bastian Kramer,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2403,PHI:2125,UniProt,C6K2F1,EMBL,GQ148552,,,IPO323,MGSTE50p,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,leaf blotch,monocots,4564,Triticum (related: wheat),cv. Riband,,,leaf,,,,MAPK signalling,reduced virulence,,,yes,yes,less extensive lesions,,,reduced; aberrant,,no,strobilurin A; sordarin; NaCl; sorbitol; H2O2; SDS; resorcinol,strobilurin A: CAS:52110-55-1; sordarin: CAS:11076-17-8; NaCl: CAS:7647-14-5; sorbitol: CAS:50-70-4; ;H2O2: CAS:7722-84-1; ;resorcinol: CAS:108-46-3,,,,,gene deletion: full; gene complementation,,,RP,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,"The deletion mutant did not exhibit any change in sensitivity/resistance to a range of different chemicals and stresses like exposure to the fungicides (strobilurin A, sordarin), salt stress (0.2 - 1.2 M NaCl), hypo- and hyperosmotic stress (range of concentrations of sorbitol up to 1.8 M), oxidative stress (5 - 100 mM H 2 O2), SDS (1 lM - 1 mM) and exposure to the wheat plant defence compound Resorcinol.",Bastian Kramer,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2404,PHI:2126,UniProt,C5J0G7,EMBL,FJ979827,,,,MGSTE12p,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,leaf blotch,monocots,4564,Triticum (related: wheat),cv. Riband,,,leaf,,,,MAPK signalling,reduced virulence,,,no,yes,delayed development of disease and smaller lesions,,,wild type,,no,strobilurin A; sordarin; NaCl; sorbitol; H2O2; SDS; resorcinol,strobilurin A: CAS:52110-55-1; sordarin: CAS:11076-17-8; NaCl: CAS:7647-14-5; sorbitol: CAS:50-70-4; ;H2O2: CAS:7722-84-1; ;resorcinol: CAS:108-46-3,,,,,gene deletion: full; gene complementation,,,RP,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,"The deletion mutant did not exhibit any change in sensitivity/resistance to a range of different chemicals and stresses like exposure to the fungicides (strobilurin A, sordarin), salt stress (0.2 - 1.2 M NaCl), hypo- and hyperosmotic stress (range of concentrations of sorbitol up to 1.8 M), oxidative stress (5 - 100 mM H 2 O2), SDS (1 lM - 1 mM) and exposure to the wheat plant defence compound Resorcinol.",Bastian Kramer,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2405,PHI:2127,UniProt,C6KEF5,EMBL,GQ183954,,,IPO323,MGSTE20p,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,leaf blotch,monocots,4564,Triticum (related: wheat),cv. Riband,,,leaf,,,,MAPK signalling,unaffected pathogenicity,,,,,,reduced,,wild type,,no,strobilurin A; sordarin; NaCl; sorbitol; H2O2; SDS; resorcinol,strobilurin A: CAS:52110-55-1; sordarin: CAS:11076-17-8; NaCl: CAS:7647-14-5; sorbitol: CAS:50-70-4; ;H2O2: CAS:7722-84-1; ;resorcinol: CAS:108-46-3,,,,,gene deletion: full; gene complementation,,,RP,19520179,PubMed,10.1016/j.fgb.2009.06.001,,foster@ibwf.de,"The deletion mutant did not exhibit any change in sensitivity/resistance to a range of different chemicals and stresses like exposure to the fungicides (strobilurin A, sordarin), salt stress (0.2 - 1.2 M NaCl), hypo- and hyperosmotic stress (range of concentrations of sorbitol up to 1.8 M), oxidative stress (5 - 100 mM H 2 O2), SDS (1 lM - 1 mM) and exposure to the wheat plant defence compound Resorcinol.",Bastian Kramer,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2406,PHI:2128,UniProt,G4N2B2,GenBank,MGG_04853.6,,,70-15,MoHox1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,,,,,reduced virulence,,no,no,,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full,,,RP,19997500,PubMed,10.1371/journal.pgen.1000757,,yongl ee@snu.ac.kr,no comments,Seryu n Kim,2009,,Kim_2009,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2407,PHI:2129,UniProt,G4MRM6,GenBank,MGG_11712.6,,,70-15,MoHox6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,,,,,reduced virulence,,no,no,no,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,19997500,PubMed,10.1371/journal.pgen.1000757,,yongl ee@snu.ac.kr,no comments,Seryu n Kim,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2408,PHI:2130,UniProt,G4N881,GenBank,MGG_06285.6,,,70-15,MoHox4,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,,,,,reduced virulence,,no,,,,reduced; aberrant,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,19997500,PubMed,10.1371/journal.pgen.1000757,,yongl ee@snu.ac.kr,no comments,Seryu n Kim,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2409,PHI:2131,UniProt,G4N8D9,GenBank,MGG_12865.6,,,70-15,MoHox7,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,,,,,loss of pathogenicity,,yes,yes,no,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,19997500,PubMed,10.1371/journal.pgen.1000757,,yongl ee@snu.ac.kr,no comments,Seryu n Kim,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2410,PHI:2132,UniProt,G4N3L5,GenBank,MGG_12958.6,,,70-15,MoHox8,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,,,,,loss of pathogenicity,,no,yes,,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,19997500,PubMed,10.1371/journal.pgen.1000757,,yongl ee@snu.ac.kr,no comments,Seryu n Kim,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2411,PHI:2133,UniProt,G4MV99,GenBank,MGG_01730.6,,,70-15,MoHox3,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,,,,,reduced virulence,,no,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,19997500,PubMed,10.1371/journal.pgen.1000757,,yongl ee@snu.ac.kr,no comments,Seryu n Kim,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2412,PHI:2134,UniProt,G4N0U1,GenBank,MGG_07437.6,,,70-15,MoHox5,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,,,,,reduced virulence,,no,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,19997500,PubMed,10.1371/journal.pgen.1000757,,yongl ee@snu.ac.kr,no comments,Seryu n Kim,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2413,PHI:2135,UniProt,B9WZW9,EMBL,AB498873,,,Ina168,AVR-Pia,,,,,,,318829,Magnaporthe oryzae,,Ina168,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sasanishiki,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response-like cell death,functional test in host,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,Yoshida-2009-Association genetics,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2414,PHI:2135,UniProt,B9WZW9,EMBL,AB498873,,,Ina168,AVR-Pia,,,,,,,318829,Magnaporthe oryzae,,Ina86-137,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sasanishiki,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2415,PHI:2135,UniProt,B9WZW9,EMBL,AB498873,,,Ina168,AVR-Pia,,,,,,,318829,Magnaporthe oryzae,,TH68-141,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sasanishiki,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2416,PHI:2136,UniProt,C4B8B7,EMBL,AB498874,,,Ina168,AVR-Pii,,,,,,,318829,Magnaporthe oryzae,,Ina168,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Hitomebore,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response-like cell death,functional test in host,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2417,PHI:2136,UniProt,C4B8B7,EMBL,AB498874,,,Ina168,AVR-Pii,,,,,,,318829,Magnaporthe oryzae,,Sasa2,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Kakehashi,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2418,PHI:2136,UniProt,C4B8B7,EMBL,AB498874,,,Ina168,AVR-Pii,,,,,,,318829,Magnaporthe oryzae,,Ina86-137,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Kakehashi,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2419,PHI:2136,UniProt,C4B8B7,EMBL,AB498874,,,Ina168,AVR-Pii,,,,,,,318829,Magnaporthe oryzae,,Sasa2,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Hitomebore,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2420,PHI:2137,UniProt,C4B8B9,EMBL,AB498876,,,Ina168,AVR-Pik,,,,,,,318829,Magnaporthe oryzae,,Ina168,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Kanto 51,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response-like cell death,functional test in host,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2421,PHI:2137,UniProt,C4B8B9,EMBL,AB498876,,,Ina168,AVR-Pik,,,,,,,318829,Magnaporthe oryzae,,Sasa2,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Kanto 51,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2422,PHI:2137,UniProt,C4B8B9,EMBL,AB498876,,,Ina168,AVR-Pik,,,,,,,318829,Magnaporthe oryzae,,Ina72,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Kanto 51,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2423,PHI:3498,UniProt,C4B8B9,EMBL,AB498876,,,Ina168,AVR-Pikm,,,,,,,318829,Magnaporthe oryzae,,Sasa2,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Tsuyuake,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2424,PHI:3498,UniProt,C4B8B9,EMBL,AB498876,,,Ina168,AVR-Pikm,,,,,,,318829,Magnaporthe oryzae,,Ina72,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Tsuyuake,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2425,PHI:3499,UniProt,C4B8B9,EMBL,AB498876,,,Ina168,AVR-Pikp,,,,,,,318829,Magnaporthe oryzae,,Sasa2,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. K60,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2426,PHI:3499,UniProt,C4B8B9,EMBL,AB498876,,,Ina168,AVR-Pikp,,,,,,,318829,Magnaporthe oryzae,,Ina72,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. K60,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,AR,19454732,PubMed,10.1105/tpc.109.066324,,terauchi@ibrc .or.jp,no comments,Kentaro Yoshida,2009,,,Batch003b,2012-02-21,MC,,,,,,,,,,,,,
,,Record 2427,PHI:2138,UniProt,G4NCF7,GenBank,XP_368148,,,70-15,SGA1,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,root; leaf,vacuolar glucoamylase,,,,unaffected pathogenicity,,yes,,,,reduced,,wild type,,no,,,,,,,gene deletion: full,,,RP,2038305,PubMed,no data found,,naweed@tll.org.sg,no comments,Yi Zhen Deng,2010,,Deng Sga1 2010,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2428,PHI:2139,UniProt,B6VCT7,EMBL,ACJ06588,,,Guy11,ATG8,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,root; leaf,autophagy,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,RP,2038305,PubMed,no data found,,naweed@tll.org.sg,no comments,Yi Zhen Deng,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2429,PHI:2138,UniProt,G4NCF7,GenBank,XP_368148,,,70-15,SGA1,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,vacuolar glucoamylase,,,,unaffected pathogenicity,,yes,,,,reduced,,wild type,,no,,,,,,,gene deletion: full,,,RP,2038305,PubMed,no data found,,naweed@tll.org.sg,no comments,Yi Zhen Deng,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2430,PHI:2139,UniProt,B6VCT7,EMBL,ACJ06588,,,Guy11,ATG8,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,autophagy,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,RP,2038305,PubMed,no data found,,naweed@tll.org.sg,no comments,Yi Zhen Deng,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2431,PHI:2138,UniProt,G4NCF7,GenBank,XP_368148,,,70-15,SGA1,,,,,,PHI:2139,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,vacuolar glucoamylase,,,,loss of pathogenicity,,yes,,,,reduced,,wild type,,no,,,,,,,gene deletion: full,,,RP,2038305,PubMed,no data found,,naweed@tll.org.sg,no comments,Yi Zhen Deng,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2432,PHI:2139,UniProt,B6VCT7,EMBL,ACJ06588,,,Guy11,ATG8,,,,,,PHI:2138,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,autophagy,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,RP,2038305,PubMed,no data found,,naweed@tll.org.sg,no comments,Yi Zhen Deng,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2433,PHI:2140,UniProt,G4MLE6,GenBank,XP_001907727.1,,,Guy11,MoVam7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,vacuolar morphogenesis,,,,loss of pathogenicity,,yes,yes,yes,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21283626,PubMed,10.1371/journal.pone.0016439,,zhgzhan g@njau.ed u.cn,no comments,Xianying Dou,2011,,"Dou-2011-MoVam7, a conserved",Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2434,PHI:2141,UniProt,G4MRZ0,GenBank,XP_001406795,,,70-15,CDC15,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,seedling; leaf,cell cycle regulation,,,,loss of pathogenicity,,yes,yes,yes,tiny necrotic lesions,reduced; aberrant,,reduced,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,21600998,PubMed,10.1016/j.fgb.2011.05.001,,yonglee@snu.ac.kr,no comments,Jaeduk Goh,2011,,Goh-2011-The cell cycle gene,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2435,PHI:2142,UniProt,G4N6V5,GenBank,XP_001408783,,,70-15,MoAP1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,mediates the oxidative stress response,,,,loss of pathogenicity,,,no,yes,small necrotic-like dark brown spots,reduced; aberrant,,reduced; aberrant,,no,H2O2; copper sulphate,H2O2: CAS:7722-84-1; copper sulpate: CAS:7758-98-7,,,,,gene disruption; gene complementation,,,RP,21383978,PubMed,10.1371/journal.ppat.1001302,,zhgzhan g@njau.ed u.cn,mutant strains are susceptible to oxidative stress and show reduced growth,Min Guo,2011,,Guo-2011-The bZIP transcripti,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2436,PHI:2142,UniProt,G4N6V5,GenBank,XP_001408783,,,70-15,MoAP1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,seedling; leaf,mediates the oxidative stress response,,,,loss of pathogenicity,,,no,yes,small necrotic-like dark brown spots,reduced; aberrant,,reduced; aberrant,,no,H2O2; copper sulphate,H2O2: CAS:7722-84-1; copper sulpate: CAS:7758-98-7,,,,,gene disruption; gene complementation,,,RP,21383978,PubMed,10.1371/journal.ppat.1001302,,zhgzhan g@njau.ed u.cn,mutant strains are susceptible to oxidative stress and show reduced growth,Min Guo,2011,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2437,PHI:2143,UniProt,G4MUF4,GenBank,MGG_01662,,,,MoVPR,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,minor extracellular protease-encoding gene,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene disruption,,,RP,21383978,PubMed,10.1371/journal.ppat.1001302,,zhgzhan g@njau.ed u.cn,no comments,Min Guo,2011,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2438,PHI:2144,UniProt,G4NAI7,GenBank,MGG_13654,,,70-15,MoAAT,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,4-aminobuty-rate aminotransferase-encoding,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,21383978,PubMed,10.1371/journal.ppat.1001302,,zhgzhan g@njau.ed u.cn,no comments,Min Guo,2011,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2439,PHI:2145,UniProt,G4MXJ4,GenBank,MGG_01230,,,70-15,MoSSADH,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,succinate-semialdehyde dehydrogenase,,,,loss of pathogenicity,,no,yes,yes,,reduced,,reduced; aberrant,,no,H2O2,H2O2: CAS:7722-84-1,,,,,gene disruption,,,RP,21383978,PubMed,10.1371/journal.ppat.1001302,,zhgzhan g@njau.ed u.cn,mutant strains are susceptible to oxidative stress and show reduced growth,Min Guo,2011,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2440,PHI:2146,,no data found,GenBank,MGG_15157,,,,MoACT,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,encoding acetyltransferase,,,,loss of pathogenicity,,no,yes,yes,tiny lesions,reduced,,reduced; aberrant,,no,H2O2,H2O2: CAS:7722-84-1,,,,,gene disruption,,,RP,21383978,PubMed,10.1371/journal.ppat.1001302,,zhgzhan g@njau.ed u.cn,mutant strains are susceptible to oxidative stress and show reduced growth,Min Guo,2011,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2441,PHI:2145,UniProt,G4MXJ4,GenBank,MGG_01230,,,70-15,MoSSADH,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,seedling; leaf,succinate-semialdehyde dehydrogenase,,,,loss of pathogenicity,,no,yes,yes,,reduced,,reduced; aberrant,,no,H2O2,H2O2: CAS:7722-84-1,,,,,gene disruption,,,RP,21383978,PubMed,10.1371/journal.ppat.1001302,,zhgzhan g@njau.ed u.cn,mutant strains are susceptible to oxidative stress and show reduced growth,Min Guo,2011,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2442,PHI:2146,,no data found,GenBank,MGG_15157,,,,MoACT,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,seedling; leaf,encoding acetyltransferase,,,,loss of pathogenicity,,no,yes,yes,tiny lesions,reduced,,reduced; aberrant,,no,H2O2,H2O2: CAS:7722-84-1,,,,,gene disruption,,,RP,21383978,PubMed,10.1371/journal.ppat.1001302,,zhgzhan g@njau.ed u.cn,mutant strains are susceptible to oxidative stress and show reduced growth,Min Guo,2011,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2443,PHI:2147,UniProt,G5EH97,GenBank,EHA46510.1,,,70-15,Erl1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,root; leaf,GTPase,,,,reduced virulence,,no,no,yes,same as wild type,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19958140,PubMed,10.1094/MPMI-23-1-0067,,Natalia.requena@bio.uka.de,no comments,Stephanie Heupel,2010,,Heupal Erl1 2010,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2444,PHI:2148,UniProt,G4N4J5,EMBL,EHA52010,,,70-15,"7,8-LDS",,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,linoleate diol synthases,,,,unaffected pathogenicity,,no,no,no,,wild type,,wild type,wild type,no,,,,,,,gene deletion: partial,,,RP,20023302,PubMed,10.1074/jbc.M109.062810,,Ernst.Oliw@farmbio.uu.se,no comments,Fredrik Jernerén,2010,,"Jerneren-2010-Gene deletion of 7,8",Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2445,PHI:2149,UniProt,G4NCK1,GenBank,MGG_01057.6,,,70-15,MoLDB1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,reduced virulence,,,yes,no,,,,,,no,,,,,,,gene disruption,,,AR,20831406,PubMed,10.1094/MPMI-03-10-0052,,zhywang@zju.edu.cn,no comments,Ya Li,2010,,Li MoLDB1,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2446,PHI:2149,UniProt,G4NCK1,GenBank,MGG_01057.6,,,70-15,MoLDB1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,,,,,reduced virulence,,,yes,no,,,,,,no,,,,,,,gene disruption,,,AR,20831406,PubMed,10.1094/MPMI-03-10-0052,,zhywang@zju.edu.cn,no comments,Ya Li,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2447,PHI:2149,UniProt,G4NCK1,GenBank,MGG_01057.6,,,70-15,MoLDB1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,loss of pathogenicity,,,yes,no,,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20831406,PubMed,10.1094/MPMI-03-10-0052,,zhywang@zju.edu.cn,no comments,Ya Li,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2448,PHI:2149,UniProt,G4NCK1,GenBank,MGG_01057.6,,,70-15,MoLDB1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,,,,,loss of pathogenicity,,yes,yes,no,,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20831406,PubMed,10.1094/MPMI-03-10-0052,,zhywang@zju.edu.cn,no comments,Ya Li,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2449,PHI:2150,UniProt,C1KJI7,EMBL,FJ842881,,,ZN04,AVR-Pita1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Yashiro-mochi,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,AR,20435900,PubMed,10.1105/tpc.109.069666,,bvalent@ks u.edu,no comments,Chang Hyun Khang,2010,,Khang-2010-Translocation of Mag,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2450,PHI:2151,UniProt,B9A9V1,EMBL,AB480169,,,,PWL1,,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,38414,Eragrostis curvula (related: weeping love grass),,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,AR,20435900,PubMed,10.1105/tpc.109.069666,,bvalent@ks u.edu,no comments,Chang Hyun Khang,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2451,PHI:2152,UniProt,Q01144,,MGU26313,,,4392-1-6,PWL2,,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,38414,Eragrostis curvula (related: weeping love grass),,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,AR,20435900,PubMed,10.1105/tpc.109.069666,,bvalent@ks u.edu,no comments,Chang Hyun Khang,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2452,PHI:2151,UniProt,B9A9V1,EMBL,AB480169,,,,PWL1,,,,,,,318829,Magnaporthe oryzae,1274781,4091-5-8,blast (rice),monocots,38414,Eragrostis curvula (related: weeping love grass),,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,AR,20435900,PubMed,10.1105/tpc.109.069666,,bvalent@ks u.edu,no comments,Chang Hyun Khang,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2453,PHI:2152,UniProt,Q01144,,MGU26313,,,4392-1-6,PWL2,,,,,,,318829,Magnaporthe oryzae,1274781,4091-5-8,blast (rice),monocots,38414,Eragrostis curvula (related: weeping love grass),,,,leaf,,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,AR,20435900,PubMed,10.1105/tpc.109.069666,,bvalent@ks u.edu,no comments,Chang Hyun Khang,2010,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2454,PHI:2153,UniProt,G4N178,GenBank,MGG_07460.6,,,70-15,MoHyr1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Maratelli,,,leaf,,,,,reduced virulence,,no,,,,wild type,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,AR,21533213,PubMed,10.1371/journal.ppat.1001335,,ndonof@udel.edu,no comments,Kun Huang,2011,,Huang-2011-HYR1-mediated detoxi,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2455,PHI:2153,UniProt,G4N178,GenBank,MGG_07460.6,,,70-15,MoHyr1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Lacey,,,leaf,,,,,reduced virulence,,no,,,pinhead-sized brown specks; 1.5 mm brown spots; 2 - 3 mm gray spots with brown margins,wild type,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,AR,21533213,PubMed,10.1371/journal.ppat.1001335,,ndonof@udel.edu,no comments,Kun Huang,2011,,,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2456,PHI:2154,UniProt,G5EI55,GenBank,MGG_02741.6,,,70-15,RBP35,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf; root,polyadenylation factor; mRNA processing,,,TOR signaling pathway; nitrogen metabolism,reduced virulence,,,no,,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,AR,22194688,PubMed,10.1371/journal.ppat.1002441,,ane.sesma@upm.es,no comments,Marina Franceschetti,2011,,Franceschetti-2011-Fungal virulence and,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2457,PHI:2155,UniProt,B8Q8Z5,EMBL,EU375307,,,Guy11,MoPEX7,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdong,,,leaf,PTS2 receptor; lipid mobilization; fatty acid utilization,,,,loss of pathogenicity,,no,yes,no,,reduced,,,wild type,no,glucose,CAS:50-99-7,,,,,gene deletion: full; gene complementation,,,AR,22194815,PubMed,10.1371/journal.pone.0028220,,yonglee@snu.ac.kr,Additional glucose treatment prior to spray inoculation partially complemented the pathogenicity defect of Mopex7 deletion mutant,Jaeduk Goh,2011,,Goh-2011-The PEX7-mediated pe,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2458,PHI:2156,UniProt,G4MZM4,,MGG_08212.6,,,70-15,Moatf1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,regulation of oxidative stress tolerance,,,,reduced virulence,,,,yes,,,,reduced,wild type,no,,,,,,production of phenolic compounds; oxidative burst,gene deletion: full; gene complementation,,,AR,20615116,PubMed,10.1094/MPMI-23-8-1053,,zhgzhang@njau.edu.cn,no comments,Min Guo,2010,,Guo Moatf1 2010,Batch004a,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2459,PHI:2158,UniProt,B5TM01,GenBank,EU984498,,,70-15,MoCMK1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,calcium/calmodulin-dependent kinase,,,calcium signalling pathway,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,19837571,PubMed,10.1016/j.micres.2009.08.007,,fuchenglin@zju.edu.cn,no comments,Xiao-Hong Liu,2010,,Liu-2010-Disruption of MoCMK1,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2460,PHI:2159,UniProt,G4N4W3,GenBank,MG06033,,,70-15,MoMSB2,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling; leaf,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,reduced,wild type,no,beeswax; paraffin; 1-octacosanol (C28); 1-triacontanol (C30),beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,no comments,Wende Liu,2011,,Lui_2011_Multiple plant surface,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2461,PHI:2160,UniProt,Q2KEW0,GenBank,MG09125,,,70-15,MoSHO1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,no,no,no,,,,wild type,wild type,no,16-hexadecanediol; cis-9-octadecen-1-ol; bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),16-hexadecanediol: CAS:7735-42-4; cis-9-octadecen-1-ol: CAS:143-28-2; beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,cutin and dewaxed response seen only in the MoSHO1 mutants in terms of appresoria formation,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2462,PHI:2159,UniProt,G4N4W3,GenBank,MG06033,,,70-15,MoMSB2,,,,,,PHI:2160,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,reduced; aberrant,reduced; aberrant,no,bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,no comments,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2463,PHI:2160,UniProt,Q2KEW0,GenBank,MG09125,,,70-15,MoSHO1,,,,,,PHI:2159,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,reduced; aberrant,reduced; aberrant,no,bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,no comments,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2464,PHI:2159,UniProt,G4N4W3,GenBank,MG06033,,,70-15,MoMSB2,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,reduced,wild type,no,bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,no comments,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2465,PHI:2160,UniProt,Q2KEW0,GenBank,MG09125,,,70-15,MoSHO1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,no,no,no,,,,wild type,wild type,no,16-hexadecanediol; cis-9-octadecen-1-ol; bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),16-hexadecanediol: CAS:7735-42-4; cis-9-octadecen-1-ol: CAS:143-28-2; beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,cutin and dewaxed response seen only in the MoSHO1 mutants in terms of appresoria formation,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2466,PHI:2159,UniProt,G4N4W3,GenBank,MG06033,,,70-15,MoMSB2,,,,,,PHI:2160,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,reduced; aberrant,reduced; aberrant,no,bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,no comments,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2467,PHI:2160,UniProt,Q2KEW0,GenBank,MG09125,,,70-15,MoSHO1,,,,,,PHI:2159,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,reduced; aberrant,reduced; aberrant,no,bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,no comments,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2468,PHI:2159,UniProt,G4N4W3,GenBank,MG06033,,,70-15,MoMSB2,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,reduced,wild type,no,bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,no comments,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2469,PHI:2160,UniProt,Q2KEW0,GenBank,MG09125,,,70-15,MoSHO1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,no,no,no,,,,wild type,wild type,no,16-hexadecanediol; cis-9-octadecen-1-ol; bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),16-hexadecanediol: CAS:7735-42-4; cis-9-octadecen-1-ol: CAS:143-28-2; beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,cutin and dewaxed response seen only in the MoSHO1 mutants in terms of appresoria formation,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2470,PHI:2159,UniProt,G4N4W3,GenBank,MG06033,,,70-15,MoMSB2,,,,,,PHI:2160,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,reduced; aberrant,reduced; aberrant,no,bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,no comments,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2471,PHI:2160,UniProt,Q2KEW0,GenBank,MG09125,,,70-15,MoSHO1,,,,,,PHI:2159,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,recognizing different chemical and physical signals present on the rice leaf surface,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,reduced; aberrant,reduced; aberrant,no,bee wax; paraffin wax; 1-octacosanol (C28); 1-triacontanol (C30),beeswax: CAS:8012-89-3; paraffin: CAS:8002-74-2; 1-octacosanol (C28): CAS:557-61-9; 1-triacontanol (C30): CAS:593-50-0,,,,,gene deletion: full; gene complementation,,,RP,21283781,PubMed,10.1371/journal.ppat.1001261,,jinrong@purdue.edu,no comments,Wende Liu,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2472,PHI:2161,UniProt,G4NGK7,,MGG_04100.6,,,70-15,SEP1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cytokinesis,,,,loss of pathogenicity,,no,yes,yes,,,,reduced,wild type; aberrant,no,,,,,,,gene mutation: characterised,,,RP,20639448,PubMed,10.1105/tpc.110.074492,,n.j.talbot@exeter.ac.uk,no comments,Diane G.O. Saunders,2010,,Saunders-2010-spatial uncoupling,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2473,PHI:2162,UniProt,G4N7T3,EMBL,EHA50887.1,,,70-15,CPKA,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,,,,,PMK1 signalling pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,Tucker-2010-common genetic pathway,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2474,PHI:2163,UniProt,G4N0Z0,EMBL,EHA52368.1,,,70-15,PMK1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,root,,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2475,PHI:2164,UniProt,G4N3L5,EMBL,EHA52690.1,,,70-15,MST12,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,root,,,,PMK1 signalling pathway,reduced virulence,,,,,,,,wild type,reduced,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2476,PHI:2165,UniProt,G4N3R9,EMBL,EHA51893.1,,,70-15,PTH11,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,,,,PKA and PKC signaling pathways,reduced virulence,,yes,,,,,,,,no,"cyclic AMP; 1,2-diacylglycerol","cyclic AMP: CAS:60-92-4; 1,2-diacylglycerol: CAS:102-62-5",,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2477,PHI:2166,UniProt,G4N4F9,EMBL,EHA52827.1,,,70-15,CBP1,,,,,,,318829,Magnaporthe oryzae,,P2,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,,,,PMK1 signalling pathway,unaffected pathogenicity,,no,,,,wild type,,wild type,wild type,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2478,PHI:2167,UniProt,G4N1A3,EMBL,EHA52374.1,,,70-15,EXP5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,,,,PMK1 signalling pathway,reduced virulence,,no,,,,,,reduced,,no,calcium chloride; galactose,calcium chloride: CAS:10035-04-8; galactose: CAS:3646-73-9,,,,,gene disruption; gene complementation,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2479,PHI:2162,UniProt,G4N7T3,EMBL,EHA50887.1,,,70-15,CPKA,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,,,,,PMK1 signalling pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2480,PHI:2163,UniProt,G4N0Z0,EMBL,EHA52368.1,,,70-15,PMK1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,root,,,,PMK1 signalling pathway,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2481,PHI:2164,UniProt,G4N3L5,EMBL,EHA52690.1,,,70-15,MST12,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,root,,,,PMK1 signalling pathway,reduced virulence,,,,,,,,wild type,reduced,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2482,PHI:2165,UniProt,G4N3R9,EMBL,EHA51893.1,,,70-15,PTH11,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf; root,,,,PKA and PKC signaling pathways,reduced virulence,,yes,,,,,,,,no,"cyclic AMP; 1,2-diacylglycerol","cyclic AMP: CAS:60-92-4; 1,2-diacylglycerol: CAS:102-62-5",,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2483,PHI:2166,UniProt,G4N4F9,EMBL,EHA52827.1,,,70-15,CBP1,,,,,,,318829,Magnaporthe oryzae,,P2,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf; root,,,,PMK1 signalling pathway,unaffected pathogenicity,,no,,,,wild type,,wild type,wild type,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2484,PHI:2167,UniProt,G4N1A3,EMBL,EHA52374.1,,,70-15,EXP5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf; root,,,,PMK1 signalling pathway,reduced virulence,,no,,,,,,reduced,,no,calcium chloride; galactose,calcium chloride: CAS:10035-04-8; galactose: CAS:3646-73-9,,,,,gene disruption; gene complementation,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2485,PHI:2168,UniProt,G4MU85,GenBank,MGG_11346.6,,,70-15,MGG_11346,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,root,,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2486,PHI:2169,UniProt,G4N027,GenBank,MGG_06188.6,,,70-15,MGG_06188.6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,root,,,,,reduced virulence,,yes,,,,aberrant,,wild type,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2487,PHI:2169,UniProt,G4N027,GenBank,MGG_06188.6,,,70-15,MGG_06188.6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,root,,,,,reduced virulence,,yes,,,,aberrant,,reduced,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2488,PHI:2170,UniProt,G4MQR5,GenBank,MGG_09312.6,,,70-15,MGG_09312.6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,root,transcription factor,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2489,PHI:2170,UniProt,G4MQR5,GenBank,MGG_09312.6,,,70-15,MGG_09312.6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,root,transcription factor,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2490,PHI:2171,UniProt,G4NJD1,GenBank,MGG_15019.6,,,70-15,Peroxisomal copper amine oxidase,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,root,Cu-amine-oxidase,,,,reduced virulence,,yes,,,,,,,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2491,PHI:2171,UniProt,G4NJD1,GenBank,MGG_15019.6,,,70-15,Peroxisomal copper amine oxidase,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,root,Cu-amine-oxidase,,,,reduced virulence,,yes,,,,,,,,no,,,,,,,gene disruption,,,RP,20348434,PubMed,10.1105/tpc.109.066340,,ane.sesma@ bbsrc.ac.uk,no comments,Sara L. Tucker,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2492,PHI:2172,UniProt,G4NHF4,GenBank,MGG_03860.6,,,70-15,TPS1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,integrates control of glucose-6-phosphate metabolism and nitrogen source utilization; regulation of nitrate metabolism,,,oxidative pentose phosphate pathway,loss of pathogenicity,,yes,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21115813,PubMed,10.1073/pnas.1006839107,,N.J.Talbot@exeter.ac.uk.,no comments,Richard A. Wilson,2010,,Wilson-2010-An NADPH -dependent,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2493,PHI:2173,UniProt,G4N9C8,GenBank,MGG_10017.6,,,70-15,NMR1,,,,,,PHI:2172,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,corepressor to control virulence-associated gene expression downstream of Tps1,,,oxidative pentose phosphate pathway,reduced virulence,,yes,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21115813,PubMed,10.1073/pnas.1006839107,,N.J.Talbot@exeter.ac.uk.,NMR genes reduced the loss of pathogenecity symptoms cause due to deletion of the TPS1 gene,Richard A. Wilson,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2494,PHI:2174,UniProt,G5EHQ9,GenBank,MGG_02860.6,,,70-15,NMR2,,,,,,PHI:2172,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,corepressor to control virulence-associated gene expression downstream of Tps1,,,oxidative pentose phosphate pathway,reduced virulence,,yes,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21115813,PubMed,10.1073/pnas.1006839107,,N.J.Talbot@exeter.ac.uk.,NMR genes reduced the loss of pathogenecity symptoms cause due to deletion of the TPS1 gene,Richard A. Wilson,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2495,PHI:2175,UniProt,G4NAJ0,GenBank,MGG_09705.6,,,70-15,NMR3,,,,,,PHI:2172,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,corepressor to control virulence-associated gene expression downstream of Tps1,,,oxidative pentose phosphate pathway,reduced virulence,,yes,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21115813,PubMed,10.1073/pnas.1006839107,,N.J.Talbot@exeter.ac.uk.,NMR genes reduced the loss of pathogenecity symptoms cause due to deletion of the TPS1 gene,Richard A. Wilson,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2496,PHI:2176,UniProt,G4N4Y2,GenBank,MGG_06050.6,,,70-15,ASD4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,transcription factor,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,RP,21115813,PubMed,10.1073/pnas.1006839107,,N.J.Talbot@exeter.ac.uk.,NMR genes reduced the loss of pathogenecity symptoms cause due to deletion of the TPS1 gene,Richard A. Wilson,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2497,PHI:2177,UniProt,G4MQP9,GenBank,MGG_09299.6,,,70-15,PAS1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,increased,,,,no,,,,,,,gene deletion: full,,,RP,21115813,PubMed,10.1073/pnas.1006839107,,N.J.Talbot@exeter.ac.uk.,NMR genes reduced the loss of pathogenecity symptoms cause due to deletion of the TPS1 gene,Richard A. Wilson,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2498,PHI:2178,UniProt,G4MNV0,EMBL,EHA57107.1,,,70-15,MoSFl1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,,,,,reduced virulence,,no,no,yes,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,21625508,PubMed,10.1371/journal.pone.0019951,,jinrong@p urdue.edu,no comments,Guotian Li,2011,,Li-2011-MoSfl1 is important,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2499,PHI:2179,UniProt,F8SM03,GenBank,HQ650870,,,70-15,Moplaa,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,phospholipase A2-activating protein,,,,reduced virulence,,yes,,,,reduced,,reduced,defective,no,,,,,,,gene deletion: full; gene complementation,,,RP,21482087,PubMed,10.1016/j.micres.2011.02.003,,fuchenglin@zju.edu.cn,no comments,Xiao-Hong Liu,2011,,Liu-2011-Identification and m-4178807552,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2500,PHI:2180,UniProt,G4N7A0,EMBL,EHA50810.1,,,70-15,MoTea4,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,regulate polarized growth and morphogenesis,,,,loss of pathogenicity,,yes,yes,yes,,reduced; aberrant,,wild type; aberrant,defective,no,,,,,,,gene deletion: full; gene complementation,,,RP,20472691,PubMed,10.1128/EC.00292-09,,naweed@tll.org.sg,no comments,Rajesh N. Patkar,2010,,Patkar-2010-MoTea mediated polarized,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2501,PHI:2180,UniProt,G4N7A0,EMBL,EHA50810.1,,,70-15,MoTea4,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,regulate polarized growth and morphogenesis,,,,loss of pathogenicity,,yes,yes,yes,,reduced; aberrant,,wild type; aberrant,defective,no,,,,,,,gene deletion: full; gene complementation,,,RP,20472691,PubMed,10.1128/EC.00292-09,,naweed@tll.org.sg,no comments,Rajesh N. Patkar,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2502,PHI:2181,UniProt,G4MRZ9,GenBank,XP_365782,,,70-15,MoDUO1,chromosome II,,,,,,318829,Magnaporthe oryzae,,Y34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling,,,,,reduced virulence,,no,yes,yes,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,21901484,PubMed,10.1007/s00294-011-0355-1,,chenyaoj@gxu.edu.cn,no comments,Haowen Peng,2011,,Peng_MoDUO1,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2503,PHI:2182,UniProt,B6VCT6,GenBank,FJ374666,,,70-15,MoAtg4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf; root,cysteine protease,,,,loss of pathogenicity,yes,yes,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,19923912,PubMed,no data found,,fuchenglin@zju.edu.cn,no comments,Tong-Bao Liu,2010,,Liu MoAtg4,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2504,PHI:2182,UniProt,B6VCT6,GenBank,FJ374666,,,70-15,MoAtg4,,,,,,,318829,Magnaporthe oryzae,,2539,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf; root,cysteine protease,,,,loss of pathogenicity,yes,yes,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,19923912,PubMed,no data found,,fuchenglin@zju.edu.cn,no comments,Tong-Bao Liu,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2505,PHI:2182,UniProt,B6VCT6,GenBank,FJ374666,,,70-15,MoAtg4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf; root,cysteine protease,,,,loss of pathogenicity,yes,yes,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,19923912,PubMed,no data found,,fuchenglin@zju.edu.cn,no comments,Tong-Bao Liu,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2506,PHI:2182,UniProt,B6VCT6,GenBank,FJ374666,,,70-15,MoAtg4,,,,,,,318829,Magnaporthe oryzae,,2539,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf; root,cysteine protease,,,,loss of pathogenicity,yes,yes,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,19923912,PubMed,no data found,,fuchenglin@zju.edu.cn,no comments,Tong-Bao Liu,2010,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2507,PHI:2183,UniProt,A4QUT2,EMBL,EHA48040.1,,,70-15,CPXB,,,,,,,318829,Magnaporthe oryzae,,Ina86-137,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling; leaf,catalase-peroxidase,,,,unaffected pathogenicity,,yes,no,,,wild type,,wild type,wild type,no,hydrogen peroxide,hydrogen peroxide: CAS:7722-84-1,,,,,gene disruption; gene complementation,,,RP,21043575,PubMed,10.1094/MPMI-07-10-0175,,eiminami@affrc.go.jp,"H2O2 at 5 mM strongly inhibited the growth of deltaCPXB strains, while the growth of the control strain and cCPXB strain exhibited approximately 50% inhibition. These results strongly suggested that CPXB is a major se-reted catalase of M. oryzae for the degradation of extracellu-lar H2O2, conferring resistance against H2O2 during vegetative growth.",Shigeru Tanabe,2011,,Tanabe Catalase-peroxidase 2011,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2508,PHI:2184,UniProt,G4NDX0,EMBL,EHA49352,,,70-15,HTF1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,positive regulator for the differentiation of conidia,,,,unaffected pathogenicity,,no,no,no,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,20192824,PubMed,10.1094/MPMI-23-4-0366,,jinrong@purdue.edu,no comments,Wende Liu,2010,,Wende Homeobox gene-3307697664,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2509,PHI:2185,UniProt,G4MUT8,EMBL,EHA54868,,,70-15,PIC1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling; leaf,,,,,unaffected pathogenicity,,no,no,no,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,21642506,PubMed,10.1128/EC.00007-11,,jinrong@purdue.edu,no comments,Haifeng Zhang,2011,,Zhang-2011-A Pmk1-interacting g,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2510,PHI:2186,UniProt,G4N6E2,EMBL,EHA49812,,,70-15,PIC5,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling; leaf,virulence factor,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,21642506,PubMed,10.1128/EC.00007-11,,jinrong@purdue.edu,no comments,Haifeng Zhang,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2511,PHI:2185,UniProt,G4MUT8,EMBL,EHA54868,,,70-15,PIC1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,,,,,unaffected pathogenicity,,no,no,no,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,21642506,PubMed,10.1128/EC.00007-11,,jinrong@purdue.edu,no comments,Haifeng Zhang,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2512,PHI:2186,UniProt,G4N6E2,EMBL,EHA49812,,,70-15,PIC5,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,leaf,virulence factor,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,21642506,PubMed,10.1128/EC.00007-11,,jinrong@purdue.edu,no comments,Haifeng Zhang,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2513,PHI:2187,UniProt,G4N3L5,EMBL,EHA52690.1,,,70-15,MST12,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling; leaf,,,,,loss of pathogenicity,,no,yes,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,21276092,PubMed,10.1111/j.1365-2958.2011.07556.x,,jinrong@purdue.edu,no comments,Xiaoying Zhou,2011,,Zhou-2011-A MADS-box transcrip,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2514,PHI:2188,UniProt,G4NJ14,EMBL,EHA46230.1,,,70-15,MoMCM1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling; leaf,,,,,reduced virulence,yes,yes,yes,yes,,reduced,reduced,reduced,aberrant,no,sorbitol; YEG; cyclic AMP,sorbitol: CAS:50-70-4; cyclic AMP: CAS:60-92-4,,,,,gene deletion: full,,,RP,21276092,PubMed,10.1111/j.1365-2958.2011.07556.x,,jinrong@purdue.edu,Momcm1 mutant has an increased sensitivity to hyperosmotic stress.The Momcm1 mutant still responded to exogenous cAMP and formed mela-nized appressoria.,Xiaoying Zhou,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2515,PHI:2187,UniProt,G4N3L5,EMBL,EHA52690.1,,,70-15,MST12,,,,,,PHI:2188,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling; leaf,,,,,loss of pathogenicity,yes,yes,yes,yes,,reduced,,reduced,aberrant,no,,,,,,,gene deletion: full,,,RP,21276092,PubMed,10.1111/j.1365-2958.2011.07556.x,,jinrong@purdue.edu,no comments,Xiaoying Zhou,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2516,PHI:2188,UniProt,G4NJ14,EMBL,EHA46230.1,,,70-15,MoMCM1,,,,,,PHI:2187,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling; leaf,,,,,loss of pathogenicity,yes,yes,yes,yes,,reduced,reduced,reduced,aberrant,no,sorbitol; YEG; cyclic AMP,sorbitol: CAS:50-70-4; cyclic AMP: CAS:60-92-4,,,,,gene deletion: full,,,RP,21276092,PubMed,10.1111/j.1365-2958.2011.07556.x,,jinrong@purdue.edu,Momcm1 mutant has an increased sensitivity to hyperosmotic stress.The Momcm1 mutant still responded to exogenous cAMP and formed mela-nized appressoria.,Xiaoying Zhou,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2517,PHI:2187,UniProt,G4N3L5,EMBL,EHA52690.1,,,70-15,MST12,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling; leaf,,,,,loss of pathogenicity,,no,yes,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,21276092,PubMed,10.1111/j.1365-2958.2011.07556.x,,jinrong@purdue.edu,no comments,Xiaoying Zhou,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2518,PHI:2188,UniProt,G4NJ14,EMBL,EHA46230.1,,,70-15,MoMCM1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling; leaf,,,,,reduced virulence,yes,yes,yes,yes,,reduced,reduced,reduced,aberrant,no,,,,,,,gene deletion: full,,,RP,21276092,PubMed,10.1111/j.1365-2958.2011.07556.x,,jinrong@purdue.edu,Momcm1 mutant has an increased sensitivity to hyperosmotic stress.The Momcm1 mutant still responded to exogenous cAMP and formed mela-nized appressoria.,Xiaoying Zhou,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2519,PHI:2187,UniProt,G4N3L5,EMBL,EHA52690.1,,,70-15,MST12,,,,,,PHI:2188,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling; leaf,,,,,loss of pathogenicity,yes,yes,yes,yes,,reduced,,reduced,aberrant,no,,,,,,,gene deletion: full,,,RP,21276092,PubMed,10.1111/j.1365-2958.2011.07556.x,,jinrong@purdue.edu,no comments,Xiaoying Zhou,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2520,PHI:2188,UniProt,G4NJ14,EMBL,EHA46230.1,,,70-15,MoMCM1,,,,,,PHI:2187,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling; leaf,,,,,loss of pathogenicity,yes,yes,yes,yes,,reduced,reduced,reduced,aberrant,no,,,,,,,gene deletion: full,,,RP,21276092,PubMed,10.1111/j.1365-2958.2011.07556.x,,jinrong@purdue.edu,Momcm1 mutant has an increased sensitivity to hyperosmotic stress.The Momcm1 mutant still responded to exogenous cAMP and formed mela-nized appressoria.,Xiaoying Zhou,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2521,PHI:2189,UniProt,G4MRA3,EMBL,EHA58228.1,,,70-15,MoGIS2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling,,,,Ras-cAMP and MAP kinase signalling pathways,reduced virulence,,no,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,21276092,PubMed,10.1111/j.1365-2958.2011.07556.x,,jinrong@purdue.edu,Momcm1 mutant has an increased sensitivity to hyperosmotic stress.The Momcm1 mutant still responded to exogenous cAMP and formed mela-nized appressoria.,Xiaoying Zhou,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2522,PHI:2189,UniProt,G4MRA3,EMBL,EHA58228.1,,,70-15,MoGIS2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,seedling,,,,Ras-cAMP and MAP kinase signalling pathways,reduced virulence,,no,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,21276092,PubMed,10.1111/j.1365-2958.2011.07556.x,,jinrong@purdue.edu,Momcm1 mutant has an increased sensitivity to hyperosmotic stress.The Momcm1 mutant still responded to exogenous cAMP and formed mela-nized appressoria.,Xiaoying Zhou,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2523,PHI:2190,UniProt,G4MRP8,EMBL,EHA58263.1,,,70-15,MoCYP51A,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,sterol 14 a-demethylase,,,,reduced virulence,no,no,,no,,reduced,wild type,wild type,,no,triadimefon; prochloraz; tebuconazole; propiconazole; diniconazole; difenoconazole; flutriafol; carbendazim; iprodione,"triadimefon: CAS:43121-43-3; prochloraz: CAS:67747-09-5; tebuconazole: CAS:107534-96-3; propiconazole: CAS:60207-90-1; diniconazole: CAS:83657-24-3; difenoconazole: CAS:119446-68-3; flutriafol: CAS:76674-21-0; carbendazim: CHEBI:3392, CAS:10605-21-7; iprodione: CHEBI:28909, CAS:36734-19-7",,,,,gene deletion: full; gene complementation,,,RP,20887796,PubMed,10.1016/j.fgb.2010.09.005,,zhywang@zju.edu.cn,"deletion of MoCYP51A, but not MoCYP51B, significantly increased sensitivity to DMI fungicides in M. oryzae.",Xia Yan,2011,,Yan-2011-A sterol 14alpha-dem,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2524,PHI:2191,UniProt,G4MZG5,EMBL,EHA53720.1,,,70-15,MoCYP51B,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,sterol 14 a-demethylase,,,,unaffected pathogenicity,no,no,,,,wild type,wild type,wild type,,no,triadimefon; prochloraz; tebuconazole; propiconazole; diniconazole; difenoconazole; flutriafol; carbendazim; iprodione,"triadimefon: CAS:43121-43-3; prochloraz: CAS:67747-09-5; tebuconazole: CAS:107534-96-3; propiconazole: CAS:60207-90-1; diniconazole: CAS:83657-24-3; difenoconazole: CAS:119446-68-3; flutriafol: CAS:76674-21-0; carbendazim: CHEBI:3392, CAS:10605-21-7; iprodione: CHEBI:28909, CAS:36734-19-7",,,,,gene deletion: full,,,RP,20887796,PubMed,10.1016/j.fgb.2010.09.005,,zhywang@zju.edu.cn,"deletion of MoCYP51A, but not MoCYP51B, significantly increased sensitivity to DMI fungicides in M. oryzae.",Xia Yan,2011,,,Batch004b,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2525,PHI:2192,UniProt,Q2LD94,EMBL,ABC60049,,,70-15,MoRgs1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,maintenance of cell wall integrity; regulation of surface hydrophobicity; regulation of intracellular cAMP levels,,,,reduced virulence,yes,no,,yes,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,No penetration defect in onion epidermal cells,Haifeng Zhang,2011,,Zhang-2011-Eight RGS and RGS-li,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2526,PHI:2193,UniProt,G4NAT9,GenBank,XP_361183,,,70-15,MoRgs2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,regulation of intracellular cAMP levels,,,,unaffected pathogenicity,,no,,no,,increased,,wild type,,no,,,,,,,gene deletion: full,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,No penetration defect in onion epidermal cells,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2527,PHI:2194,UniProt,G4N6G5,GenBank,XP_360603,,,70-15,MoRgs3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,regulation of intracellular cAMP levels,,,,reduced virulence,,no,,yes (data not shown),,increased,,wild type,,no,,,,,,,gene deletion: full,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,Penetration defect seen in in onion epidermal cells,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2528,PHI:2195,UniProt,G4ND33,GenBank,XP_368254,,,70-15,MoRgs4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,regulation of surface hydrophobicity; regulation of extracellular laccase and peroxidase activities; regulation of intracellular cAMP levels,,,,reduced virulence,yes,no,,yes,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,No penetration defect in onion epidermal cells,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2529,PHI:2196,UniProt,G4NFS7,GenBank,XP_363151,,,70-15,MoRgs5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,regulation of intracellular cAMP levels,,,,unaffected pathogenicity,,no,,no,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,No penetration defect in onion epidermal cells,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2530,PHI:2197,UniProt,G5EHY2,GenBank,XP_364773,,,70-15,MoRgs6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,regulation of intracellular cAMP levels,,,,unaffected pathogenicity,,no,,no,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,No penetration defect in onion epidermal cells,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2531,PHI:2198,UniProt,G4NF12,GenBank,XP_001411659,,,70-15,MoRgs7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,regulation of intracellular cAMP levels,,,,reduced virulence,,no,,yes,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,Penetration defect seen in in onion epidermal cells,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2532,PHI:2199,UniProt,G4N2V0,GenBank,XP_001405673,,,70-15,MoRgs8,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,regulation of intracellular cAMP levels,,,,unaffected pathogenicity,,no,,no,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,No penetration defect in onion epidermal cells,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2533,PHI:2192,UniProt,Q2LD94,EMBL,ABC60049,,,70-15,MoRgs1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,maintenance of cell wall integrity; regulation of surface hydrophobicity; regulation of intracellular cAMP levels,,,,reduced virulence,yes,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,no comments,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2534,PHI:2195,UniProt,G4ND33,GenBank,XP_368254,,,70-15,MoRgs4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,regulation of surface hydrophobicity; regulation of extracellular laccase and peroxidase activities; regulation of intracellular cAMP levels,,,,reduced virulence,yes,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,no comments,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2535,PHI:2192,UniProt,Q2LD94,EMBL,ABC60049,,,70-15,MoRgs1,,,,,,PHI:2195,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,no comments,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2536,PHI:2195,UniProt,G4ND33,GenBank,XP_368254,,,70-15,MoRgs4,,,,,,PHI:2192,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,AR,22241981,PubMed,10.1371/journal.ppat.1002450,,zhgzhang@njau.edu.cn,no comments,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2537,PHI:2200,UniProt,G4MV04,EMBL,EHA55738.1,,,70-15,MoSLN1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,contributes to osmo-adaptation; maintenance of cell wall integrity; oxidative signaling; regulation of extracellular laccase and peroxidase activities,,,,loss of pathogenicity,,,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20848286,PubMed,10.1007/s00294-010-0319-x,,zhgzhang@njau.edu.cn,no comments,Haifeng Zhang,2010,,Zhang_CurGen_MoSLN12010,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2538,PHI:2200,UniProt,G4MV04,EMBL,EHA55738.1,,,70-15,MoSLN1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,seedling; leaf,contributes to osmo-adaptation; maintenance of cell wall integrity; oxidative signaling; regulation of extracellular laccase and peroxidase activities,,,,loss of pathogenicity,,,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20848286,PubMed,10.1007/s00294-010-0319-x,,zhgzhang@njau.edu.cn,no comments,Haifeng Zhang,2010,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2539,PHI:2201,UniProt,D0ERY8,EMBL,GQ869476,,,70-15,PdeL,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,regulation of intracellular cAMP levels; regulation of extracellular laccase and peroxidase activities,,,,unaffected pathogenicity,,no,,no,,reduced; aberrant,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,AR,21386978,PubMed,10.1371/journal.pone.0017241,,zhgzhan g@njau.ed u.cn,no comments,Haifeng Zhang,2011,,Zhang-2011-Two phosphodiesteras,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2540,PHI:2202,UniProt,D0ERY7,EMBL,GQ869475,,,70-15,PdeH,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,maintenance of cell wall integrity; regulation of surface hydrophobicity; regulation of intracellular cAMP levels; regulation of extracellular laccase and peroxidase activities,,,,reduced virulence,,no,,yes,,reduced; aberrant,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,AR,21386978,PubMed,10.1371/journal.pone.0017241,,zhgzhan g@njau.ed u.cn,no comments,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2541,PHI:2201,UniProt,D0ERY8,EMBL,GQ869476,,,70-15,PdeL,,,,,,PHI:2202,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,maintenance of cell wall integrity; regulation of surface hydrophobicity; regulation of intracellular cAMP levels; regulation of extracellular laccase and peroxidase activities,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,AR,21386978,PubMed,10.1371/journal.pone.0017241,,zhgzhan g@njau.ed u.cn,no comments,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2542,PHI:2202,UniProt,D0ERY7,EMBL,GQ869475,,,70-15,PdeH,,,,,,PHI:2201,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,maintenance of cell wall integrity; regulation of surface hydrophobicity; regulation of intracellular cAMP levels; regulation of extracellular laccase and peroxidase activities,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,AR,21386978,PubMed,10.1371/journal.pone.0017241,,zhgzhan g@njau.ed u.cn,no comments,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2543,PHI:2203,UniProt,G4MU26,EMBL,EHA55626.1,,,70-15,Transcription factor,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,melanin biosynthesis; regulation of transcription,GO:0042438; GO:0006355,GO,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,AR,21386978,PubMed,10.1371/journal.pone.0017241,,zhgzhan g@njau.ed u.cn,no comments,Haifeng Zhang,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2544,PHI:2204,UniProt,G4MTF8,GenBank,MGG_01542.6,,,70-15,"endo-1,4-beta-xylanase [GH10 family]",,,,,,PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,Nguyen-2011-Simultaneous silenci,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2545,PHI:2205,UniProt,G4MTF9,GenBank,MGG_01543.6,,,70-15,JmjC domain-containing protein 5 [GH10 family],,,,,,PHI:2204; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2546,PHI:2206,UniProt,G4NBN8,GenBank,MGG_14243.6,,,70-15,"endo-1,4-beta-xylanase precursor [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2547,PHI:2207,UniProt,G4MPQ7,GenBank,MGG_02245.6,,,70-15,"endo-1,4-beta-xylanase [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2548,PHI:2208,UniProt,G4MLU0,GenBank,MGG_05464.6,,,70-15,"endo-1,4-beta-xylanase [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2549,PHI:2209,UniProt,G4N1Y8,GenBank,MGG_07868.6,,,70-15,"endo-1,4-beta-xylanase [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2550,PHI:2210,UniProt,G4MVY2,GenBank,MGG_08401.6,,,70-15,"endo-1,4-beta-xylanase B [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2551,PHI:2211,UniProt,G4MWS3,GenBank,MGG_08331.6,,,70-15,"endo-1,4-beta-xylanase B [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2552,PHI:2212,,no data found,GenBank,MGG_06593.6,,,70-15,"endo-1,4-beta-xylanase 2 [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2553,PHI:2213,UniProt,P0CT49,GenBank,MGG_07955.6,,,70-15,"endo-1,4-beta-xylanase I [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2554,PHI:2214,UniProt,G4NA54,GenBank,MGG_08424.6,,,70-15,"endo-1,4-beta-xylanase I [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Nakaizumi,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2555,PHI:2204,UniProt,G4MTF8,GenBank,MGG_01542.6,,,70-15,"endo-1,4-beta-xylanase [GH10 family]",,,,,,PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2556,PHI:2205,UniProt,G4MTF9,GenBank,MGG_01543.6,,,70-15,JmjC domain-containing protein 5 [GH10 family],,,,,,PHI:2204; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2557,PHI:2206,UniProt,G4NBN8,GenBank,MGG_14243.6,,,70-15,"endo-1,4-beta-xylanase precursor [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2558,PHI:2207,UniProt,G4MPQ7,GenBank,MGG_02245.6,,,70-15,"endo-1,4-beta-xylanase [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2559,PHI:2208,UniProt,G4MLU0,GenBank,MGG_05464.6,,,70-15,"endo-1,4-beta-xylanase [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2560,PHI:2209,UniProt,G4N1Y8,GenBank,MGG_07868.6,,,70-15,"endo-1,4-beta-xylanase [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2210; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2561,PHI:2210,UniProt,G4MVY2,GenBank,MGG_08401.6,,,70-15,"endo-1,4-beta-xylanase B [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2211; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2562,PHI:2211,UniProt,G4MWS3,GenBank,MGG_08331.6,,,70-15,"endo-1,4-beta-xylanase B [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2212; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2563,PHI:2212,,no data found,GenBank,MGG_06593.6,,,70-15,"endo-1,4-beta-xylanase 2 [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2213; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2564,PHI:2213,UniProt,P0CT49,GenBank,MGG_07955.6,,,70-15,"endo-1,4-beta-xylanase I [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2214,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2565,PHI:2214,UniProt,G4NA54,GenBank,MGG_08424.6,,,70-15,"endo-1,4-beta-xylanase I [GH10 family]",,,,,,PHI:2204; PHI:2205; PHI:2206; PHI:2207; PHI:2208; PHI:2209; PHI:2210; PHI:2211; PHI:2212; PHI:2213,318829,Magnaporthe oryzae,,Br48,blast (rice),monocots,4564,Triticum (related: wheat),cv. Norin 4,,,leaf,"endo-beta-1,4 xylanase",,,,reduced virulence,,yes,yes,yes,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21696466,PubMed,10.1111/j.1365-2958.2011.07746.x,,hnakaya@kobe-u.ac.jp,no comments,Quoc Bao Nguyen,2011,,,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2566,PHI:2215,UniProt,G4N983,EMBL,EHA50327.1,,,70-15,BIM1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,regulation of cell cycle,,,,reduced virulence,,yes,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,20190078,PubMed,10.1105/tpc.109.072447,,n.j.talbot@exeter.ac.uk,Disease symptoms caused by bim1 F1763* mutants were significantly reduced at the semirestrictive temperature of 29 deg C,Diane G.O. Saunders,2010,,Saunders-2010-Cell cycle-mediated,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2567,PHI:2216,UniProt,A0N0D1,GenBank,EF062504,,,,PemG1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdong,,,,protein elicitor,,,ca2+ dependent signaling pathway/salicylic acid signaling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,PemG1 induces transient expression of pathogen related genes in rice and increases resistance to other bacterial infections,functional test in host,,,RP,21770770,PubMed,10.1094/MPMI-01-11-0003,,m98sun@mail.hzau.edu.cn,no comments,Dong-Hai Peng,2011,,Peng PemG1 2011,Batch004c,2012-03-21,MC,,,,,,,,,,,,,
,,Record 2568,PHI:2217,UniProt,Q4PD26,GenBank,XP_758134,,,521,pep1,chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,regulates plant defense responses,,,,loss of pathogenicity,no,no,yes,,large necrotic areas,,,wild type,,no,,,,,,accumulation of H2O2; induction of defense related genes; transcriptional inhibition of genes associated with jasmonate biosynthesis,gene deletion: full; gene complementation,,,AR,19197359,PubMed,10.1371/journal.ppat.1000290,,kahma nn@mpi -marburg.mpg.de,"Complementation with a truncated allele of pep1, pep1 Del141 - 178 was able to restore pathogenicity. cysteine residues at positions 59,75,94 and 112 contribute to pathogenicity",Gunthe r Doehlemann,2009,,"Doehlemann-2009-Pep1, a Secreted Eff",Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2569,PHI:2217,UniProt,Q4PD26,GenBank,XP_758134,,,521,pep1,chromosome 3,,,,,,5270,Ustilago maydis,559306,FB1,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,regulates plant defense responses,,,,loss of pathogenicity,no,no,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,AR,19197359,PubMed,10.1371/journal.ppat.1000290,,kahma nn@mpi -marburg.mpg.de,no comments,Gunthe r Doehlemann,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2570,PHI:2217,UniProt,Q4PD26,GenBank,XP_758134,,,521,pep1,chromosome 3,,,,,,5270,Ustilago maydis,,FB2,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,regulates plant defense responses,,,,loss of pathogenicity,no,no,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,AR,19197359,PubMed,10.1371/journal.ppat.1000290,,kahma nn@mpi -marburg.mpg.de,no comments,Gunthe r Doehlemann,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2571,PHI:2217,UniProt,Q4PD26,GenBank,XP_758134,,,521,pep1,chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,regulates plant defense responses,,,,loss of pathogenicity,no,no,yes,,large necrotic areas,,,wild type,,no,,,,,,accumulation of H2O2; induction of defense related genes; transcriptional inhibition of genes associated with jasmonate biosynthesis,gene deletion: full; gene complementation,,,AR,19197359,PubMed,10.1371/journal.ppat.1000290,,kahma nn@mpi -marburg.mpg.de,Deleted um-pep1 was complemented with pep1 from U. hordei,Gunthe r Doehlemann,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2572,PHI:2218,UniProt,Q4PFH2,GenBank,XP_757288,,,521,drf1,,,,,,,5270,Ustilago maydis,,,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,no,,,,,,,defective,,no,,,,,,,gene deletion: full,,,AR,21625538,PubMed,10.1371/journal.ppat.1002044,,sand rock@staff.uni-mar burg.de,no comments,Johann es Freitag,2011,,Freitag-2011-Septation of Infecti,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2573,PHI:2218,UniProt,Q4PFH2,GenBank,XP_757288,,,521,drf1,,,,,,,5270,Ustilago maydis,,SG200AM1,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,no,yes,yes,no,,,,defective,,no,,,,,,,gene deletion: full,,,AR,21625538,PubMed,10.1371/journal.ppat.1002044,,sand rock@staff.uni-mar burg.de,no comments,Johann es Freitag,2011,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2574,PHI:2219,UniProt,Q4PBU5,GenBank,XP_758565,,,521,don1,,,,,,,5270,Ustilago maydis,,SG200AM1,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,yes,,no,,,,,,no,,,,,,,gene deletion: full,,,AR,21625538,PubMed,10.1371/journal.ppat.1002044,,sand rock@staff.uni-mar burg.de,no comments,Johann es Freitag,2011,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2575,PHI:2220,UniProt,Q4P2X0,GenBank,XP_761690,,,521,don3,,,,,,,5270,Ustilago maydis,,SG200AM1,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,yes,,no,,,,,,no,,,,,,,gene deletion: full,,,AR,21625538,PubMed,10.1371/journal.ppat.1002044,,sand rock@staff.uni-mar burg.de,no comments,Johann es Freitag,2011,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2576,PHI:2221,UniProt,Q4PHD3,GenBank,XP_756627,,,521,Msb2,,,,,,PHI:2222,5270,Ustilago maydis,559306,FB1,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,no,,,,necrotic lesions,,,,,no,,,,,,,gene deletion: full,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,no comments,Daniel Lanver,2010,,Lanver-2010-Sho1 and Msb2-Relate,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2577,PHI:2222,UniProt,Q4P9Q7,GenBank,XP_759303,,,521,Sho1,,,,,,PHI:2221,5270,Ustilago maydis,559306,FB1,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,no,,,,necrotic lesions,,,,,no,,,,,,,gene deletion: full,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,no comments,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2578,PHI:2221,UniProt,Q4PHD3,GenBank,XP_756627,,,521,Msb2,,,,,,PHI:2222,5270,Ustilago maydis,,FB2,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,no,,,,necrotic lesions,,,,,no,,,,,,,gene deletion: full,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,no comments,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2579,PHI:2222,UniProt,Q4P9Q7,GenBank,XP_759303,,,521,Sho1,,,,,,PHI:2221,5270,Ustilago maydis,,FB2,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,no,,,,necrotic lesions,,,,,no,,,,,,,gene deletion: full,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,no comments,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2580,PHI:2221,UniProt,Q4PHD3,GenBank,XP_756627,,,521,Msb2,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,yes,,,,tumors,,,,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,"both SG200AM1 sho1 deleted and SG200AM1 msb2 deleted were significantly reduced in appressorium formation compared with SG200AM1, while SG200AM1 sho1 deleted/msb2 deleted did not develop any appressoria. / transmembrane domain of Msb2 is essential for processing and function of Msb2.",Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2581,PHI:2222,UniProt,Q4P9Q7,GenBank,XP_759303,,,521,Sho1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,yes,,,,tumors,,,,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,"Both SG200AM1 sho1 deleted and SG200AM1 msb2 deleted were significantly reduced in appressorium formation compared with SG200AM1, while SG200AM1 sho1 deleted/msb2 deleted did not develop any appressoria",Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2582,PHI:2221,UniProt,Q4PHD3,GenBank,XP_756627,,,521,Msb2,,,,,,PHI:2222,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,yes,,,,necrotic lesions,,,,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,"Both SG200AM1 sho1 deleted and SG200AM1 msb2 deleted were significantly reduced in appressorium formation compared with SG200AM1, while SG200AM1 sho1 deleted/msb2 deleted did not develop any appressoria",Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2583,PHI:2222,UniProt,Q4P9Q7,GenBank,XP_759303,,,521,Sho1,,,,,,PHI:2221,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,yes,,,,necrotic lesions,,,,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,"Both SG200AM1 sho1 deleted and SG200AM1 msb2 deleted were significantly reduced in appressorium formation compared with SG200AM1, while SG200AM1 sho1 deleted/msb2 deleted did not develop any appressoria",Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2584,PHI:2221,UniProt,Q4PHD3,GenBank,XP_756627,,,521,Msb2,,,,,,PHI:2222; PHI:2223,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,unaffected pathogenicity,,,no,no,chlorotic areas and anthocyanin production,,,,,no,,,,,,,gene deletion: full,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,no comments,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2585,PHI:2222,UniProt,Q4P9Q7,GenBank,XP_759303,,,521,Sho1,,,,,,PHI:2221; PHI:2223,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,unaffected pathogenicity,,,no,no,chlorotic areas and anthocyanin production,,,,,no,,,,,,,gene deletion: full,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,no comments,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2586,PHI:2223,UniProt,Q4P862,GenBank,XP_759848,,,521,rok1,,,,,,PHI:2221; PHI:2222,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,unaffected pathogenicity,,,no,no,chlorotic areas and anthocyanin production,,,,,no,,,,,,,gene deletion: full,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,no comments,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2587,PHI:2224,UniProt,Q99078,EMBL,U07801,,,521,fuz7,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,unaffected pathogenicity,,,,,predominantly large tumors,,,,,no,,,,,,,functional test in host,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,no comments,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2588,PHI:2221,UniProt,Q4PHD3,GenBank,XP_756627,,,521,Msb2,,,,,,PHI:2222; PHI:2224,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly chlorosis and large tumors,,,,,no,arabinose,CAS:147-81-9,,,,,functional test in host,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,Sho1 and Msb2 act upstream of the MAP kinases Kpp2 and Kpp6.,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2589,PHI:2222,UniProt,Q4P9Q7,GenBank,XP_759303,,,521,Sho1,,,,,,PHI:2221; PHI:2224,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly chlorosis and large tumors,,,,,no,arabinose,CAS:147-81-9,,,,,functional test in host,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,Sho1 and Msb2 act upstream of the MAP kinases Kpp2 and Kpp6.,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2590,PHI:2224,UniProt,Q99078,EMBL,U07801,,,521,fuz7,,,,,,PHI:2221; PHI:2222,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly chlorosis and large tumors,,,,,no,arabinose,CAS:147-81-9,,,,,functional test in host,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,Sho1 and Msb2 act upstream of the MAP kinases Kpp2 and Kpp6.,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2591,PHI:2222,UniProt,Q4P9Q7,GenBank,XP_759303,,,521,Sho1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly chlorosis,,,,,no,,,,,,,gene mutation: characterised,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,no comments,Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2592,PHI:2225,UniProt,Q86ZC3,GenBank,AJ505152,,,521,kpp6,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly necrosis,,,,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,"In SG200 Del kpp6 derivatives expressing kpp6P130A P131A mutant, virulence was elevated compared with SG200 Del kpp6/otef:kpp6, and the expression of kpp6 Del 1-169 in SG200 Del kpp6 led to a further increase in virulence.",Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2593,PHI:2225,UniProt,Q86ZC3,GenBank,AJ505152,,,521,kpp6,,,,,,PHI:2222,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,loss of pathogenicity,,,,,predominantly small tumors,,,,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,"When kpp6 alleles were introduced in SG200 sho1/kpp6 double deletion mutant, which is unable to cause disease, symptom development was restored to the same extent with both the wild-type allele and the kpp6P130A P131A allele. Introduction of the kpp6 Del 1-169 mutant allele led to increased virulence compared with that of kpp6 or kpp6P130A P131A. The virulence enhancing effect of the kpp6 Del 1-169 allele was significantly higher in the sho1/kpp6 double deletion background than in the Del kpp6 background. N terminus of Kpp6 as well as the PRD alone have a negative role during virulence.",Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2594,PHI:2222,UniProt,Q4P9Q7,GenBank,XP_759303,,,521,Sho1,,,,,,PHI:2225,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,loss of pathogenicity,,,,,predominantly small tumors,,,,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20587773,PubMed,10.1105/tpc.109.073734,,kahmann@ mpi-marburg. mpg.de,"When kpp6 alleles were introduced in SG200 sho1/kpp6 double deletion mutant, which is unable to cause disease, symptom development was restored to the same extent with both the wild-type allele and the kpp6P130A P131A allele. Introduction of the kpp6 Del 1-169 mutant allele led to increased virulence compared with that of kpp6 or kpp6P130A P131A. The virulence enhancing effect of the kpp6 Del 1-169 allele was significantly higher in the sho1/kpp6 double deletion background than in the Del kpp6 background. N terminus of Kpp6 as well as the PRD alone have a negative role during virulence.",Daniel Lanver,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2595,PHI:2226,UniProt,Q4P9K9,GenBank,XP_759351,,,521,Mcs1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,,,,,reduced virulence,,,,,local chlorosis; necrotic spots,,,,,no,,,,,,oxidative burst,gene deletion: full; gene complementation,,,AR,20663961,PubMed,10.1105/tpc.110.075028,,g.steinb erg@exeter.ac.uk,no comments,Steffi Treitschke,2010,,Treitschke-2010-The Myosin Motor Dom,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2596,PHI:2226,UniProt,Q4P9K9,GenBank,XP_759351,,,521,Mcs1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,,,,,reduced virulence,,,,,local chlorosis; necrotic spots,,,,,no,,,,,,oxidative burst,gene mutation: characterised,,,AR,20663961,PubMed,10.1105/tpc.110.075028,,g.steinb erg@exeter.ac.uk,"The degree to which the plant reacts differs between the mutants, with defects in the CHS domain eliciting the strongest reaction of the plant defense system",Steffi Treitschke,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2597,PHI:2226,UniProt,Q4P9K9,GenBank,XP_759351,,,521,Mcs1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,,,,,reduced virulence,,,,,local chlorosis; necrotic spots; small tumors,,,,,no,,,,,,oxidative burst,gene mutation: characterised,,,AR,20663961,PubMed,10.1105/tpc.110.075028,,g.steinb erg@exeter.ac.uk,"The degree to which the plant reacts differs between the mutants, with defects in the CHS domain eliciting the strongest reaction of the plant defense system",Steffi Treitschke,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2598,PHI:2226,UniProt,Q4P9K9,GenBank,XP_759351,,,521,Mcs1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,,,,,reduced virulence,,,,,local chlorosis; necrotic spots,,,,,no,,,,,,oxidative burst,gene mutation: characterised,,,AR,20663961,PubMed,10.1105/tpc.110.075028,,g.steinb erg@exeter.ac.uk,"The degree to which the plant reacts differs between the mutants, with defects in the CHS domain eliciting the strongest reaction of the plant defense system",Steffi Treitschke,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2599,PHI:2227,UniProt,D4III8,GenBank,FN689796,,,521,pao,"chromosome 20, contig 214: 152339 - 1540721",,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,seedling,polyamine oxidase,,,,reduced virulence,no,,,,small tumours,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,AR,20840600,PubMed,10.1111/j.1567-1364.2010.00675.x,,jruiz@ira.cinvestav.mx,no comments,Laura Valdes-Santiago,2010,,Valdes-Santiago-2010-Life without putresc,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2600,PHI:2227,UniProt,D4III8,GenBank,FN689796,,,521,pao,"chromosome 20, contig 214: 152339 - 1540721",,,,,PHI:2228,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,seedling,polyamine oxidase,,,,loss of pathogenicity,no,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,AR,20840600,PubMed,10.1111/j.1567-1364.2010.00675.x,,jruiz@ira.cinvestav.mx,no comments,Laura Valdes-Santiago,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2601,PHI:2228,UniProt,O14439,EMBL,X88796,,,521,odc,,,,,,PHI:2227,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,seedling,polyamine oxidase,,,,loss of pathogenicity,no,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,AR,20840600,PubMed,10.1111/j.1567-1364.2010.00675.x,,jruiz@ira.cinvestav.mx,no comments,Laura Valdes-Santiago,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2602,PHI:2229,UniProt,Q4P862,GenBank,XP_759848,,,521,rok1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,unaffected pathogenicity,,,no,,tumors,,,,,no,,,,,,,gene deletion: full; gene complementation,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,Di Stasio-2009-The dual specificity,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2603,PHI:2230,UniProt,Q9UQY5,EMBL,AF193614,,,521,kpp2,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly small tumors,,,,,no,,,,,,,gene deletion: full,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2604,PHI:2229,UniProt,Q4P862,GenBank,XP_759848,,,521,rok1,,,,,,PHI:2230,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly small tumors,,,,,no,,,,,,,gene deletion: full,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2605,PHI:2230,UniProt,Q9UQY5,EMBL,AF193614,,,521,kpp2,,,,,,PHI:2229,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly small tumors,,,,,no,,,,,,,gene deletion: full,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2606,PHI:2231,UniProt,Q86ZC3,GenBank,AJ505152,,,521,kpp6,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly small tumors,,,,,no,,,,,,,gene mutation,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2607,PHI:2231,UniProt,Q86ZC3,GenBank,AJ505152,,,521,kpp6,,,,,,PHI:2229,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly small tumors,,,,,no,,,,,,,gene mutation,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2608,PHI:2229,UniProt,Q4P862,GenBank,XP_759848,,,521,rok1,,,,,,PHI:2231,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly small tumors,,,,,no,,,,,,,gene mutation,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2609,PHI:2230,UniProt,Q9UQY5,EMBL,AF193614,,,521,kpp2,,,,,,PHI:2231,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2610,PHI:2231,UniProt,Q86ZC3,GenBank,AJ505152,,,521,kpp6,,,,,,PHI:2230,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2611,PHI:2229,UniProt,Q4P862,GenBank,XP_759848,,,521,rok1,,,,,,PHI:2230; PHI:2231,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2612,PHI:2230,UniProt,Q9UQY5,EMBL,AF193614,,,521,kpp2,,,,,,PHI:2229; PHI:2231,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2613,PHI:2231,UniProt,Q86ZC3,GenBank,AJ505152,,,521,kpp6,,,,,,PHI:2229; PHI:2230,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2614,PHI:2229,UniProt,Q4P862,GenBank,XP_759848,,,521,rok1,,,,,,,5270,Ustilago maydis,,CL13,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,unaffected pathogenicity,,,,,tumors,,,,,no,,,,,,,gene deletion: full,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2615,PHI:2229,UniProt,Q4P862,GenBank,XP_759848,,,521,rok1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,,,,,reduced virulence,,,,,predominantly chlorosis,,,,,no,,,,,,,functional test in host,,,AR,19486294,PubMed,10.1111/j.1365-2958.2009.06747.x,,kahmann@mpi-marburg.mpg.de,no comments,Maurizio Di Stasio,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2616,PHI:2233,UniProt,Q4P5N0,GenBank,um04583.1,,,521,Smu1,,,,,,,5270,Ustilago maydis,,FB,smut (corn),monocots,4577,Zea mays (related: maize),,,,leaf; stem,putative protein-arginine methyltransferases,,,,reduced virulence,yes,,,,,,,aberrant; reduced,,no,7-diethylamino-4-methylcoumarin; Congo red,7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0,,,,,gene disruption,,,RP,21622903,PubMed,10.1128/EC.00237-10,,mhperl01@gwise.louisville.edu,no comments,C. Ben Lovely,2011,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2617,PHI:2233,UniProt,Q4P5N0,GenBank,um04583.1,,,521,Smu1,,,,,,,5270,Ustilago maydis,,FB,smut (corn),monocots,4577,Zea mays (related: maize),,,,leaf; stem,putative protein-arginine methyltransferases,,,,reduced virulence,yes,,,,,,,aberrant; increased,,no,7-diethylamino-4-methylcoumarin; Congo red,7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0,,,,,altered gene expression / gene regulation: overexpression,,,RP,21622903,PubMed,10.1128/EC.00237-10,,mhperl01@gwise.louisville.edu,no comments,C. Ben Lovely,2011,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2618,PHI:2233,UniProt,Q4P5N0,GenBank,um04583.1,,,521,Smu1,,,,,,PHI:2232,5270,Ustilago maydis,,FB,smut (corn),monocots,4577,Zea mays (related: maize),,,,leaf; stem,putative protein-arginine methyltransferases,,,,reduced virulence,,,,,,,,aberrant; defective,,no,7-diethylamino-4-methylcoumarin; Congo red,7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0; DAPI: CAS:28718-90-3,,,,,altered gene expression / gene regulation: overexpression,,,RP,21622903,PubMed,10.1128/EC.00237-10,,mhperl01@gwise.louisville.edu,no comments,C. Ben Lovely,2011,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2619,PHI:2234,UniProt,Q4P2D2,GenBank,um05731,,,,Cmu1,,,,,,,5270,Ustilago maydis,,CL13,smut (corn),monocots,4577,Zea mays (related: maize),,,,leaf,chorismate mutases,,,phenylpropanoid pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21976020,PubMed,10.1038/nature10454,,kahmann@mpi-marburg.mpg.de,no comments,Armin Djamei,2011,,Djamei-2011-Metabolic priming by-2939164564,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2620,PHI:2234,UniProt,Q4P2D2,GenBank,um05731,,,,Cmu1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,leaf,chorismate mutases,,,phenylpropanoid pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21976020,PubMed,10.1038/nature10454,,kahmann@mpi-marburg.mpg.de,no comments,Armin Djamei,2011,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2621,PHI:2234,UniProt,Q4P2D2,GenBank,um05731,,,,Cmu1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,leaf,chorismate mutases,,,phenylpropanoid pathway,loss of pathogenicity,,,,yes,,,,,,no,,,,,,"strong host response elicited by SG200Dcmu1-cmu1R183A,K194A mutant",gene mutation: characterised,,,RP,21976020,PubMed,10.1038/nature10454,,kahmann@mpi-marburg.mpg.de,Loss of pathogenicity with deletion mutant and dominant effect of the mutation when introduced with functional allele,Armin Djamei,2011,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2622,PHI:2234,UniProt,Q4P2D2,GenBank,um05731,,,,Cmu1,,,,,,,5270,Ustilago maydis,,CL13,smut (corn),monocots,4577,Zea mays (related: maize),,,,leaf,chorismate mutases,,,phenylpropanoid pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,21976020,PubMed,10.1038/nature10454,,kahmann@mpi-marburg.mpg.de,no comments,Armin Djamei,2011,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2623,PHI:2235,UniProt,Q4PET9,GenBank,XP_757521.1,,,521,Pit1 (um01374),chromosome 2,SG200deltapit1 (deletion construct containing hygromycin resistance marker),,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,,encode secreted effectors,,,,reduced virulence,,no,no,yes,"no tumors, only necrotic lesions",,,wild type,,no,,,,,,elevated host response,gene deletion: full; gene complementation,,,RP,21692877,PubMed,10.1111/j.1365-2958.2011.07728.x,,kahmann@mpi-marburg.mpg.de,Pit1 transformed into Pit1 deletion mutant restored virulence,Gunther Doehlemann,2011,,Doehlemann-2011-Two linked genes enc-2570066068,Batch005 / AC checked for first host targets,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2624,PHI:2236,UniProt,Q4PET8,GenBank,XP_757522,,,521,Pit2 (um01375),chromosome 2,SG200deltapit2 (deletion construct containing hygromycin resistance marker),,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,,encode secreted effectors,,,,reduced virulence,,no,no,yes,"no tumors, only necrotic lesions",,,wild type,,no,,,,,,elevated host response,gene deletion: full; gene complementation,,,RP,21692877,PubMed,10.1111/j.1365-2958.2011.07728.x,,kahmann@mpi-marburg.mpg.de,Pit2 transformed into Pit2 deletion mutant restored virulence,Gunther Doehlemann,2011,,Doehlemann-2011-Two linked genes enc-2570066068,Batch005 / AC checked for first host targets,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2625,PHI:2237,UniProt,Q4P9P1,GenBank,um03172,,,,Rbf1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,,zinc-finger transcription factor,,,,loss of pathogenicity,,yes,yes,,,,,aberrant; reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20700446,PubMed,10.1371/journal.ppat.1001035,,joe rg.kaemper@kit.e du,no comments,Kai Heimel,2010,,Heimel-2010-The Transcription Fa-3291487124,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2626,PHI:2237,UniProt,Q4P9P1,GenBank,um03172,,,,Rbf1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),,,,,zinc-finger transcription factor,,,,loss of pathogenicity,,yes,yes,,,,,aberrant; reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20700446,PubMed,10.1371/journal.ppat.1001035,,joe rg.kaemper@kit.e du,no comments,Kai Heimel,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2627,PHI:2237,UniProt,Q4P9P1,GenBank,um03172,,,,Rbf1,,,,,,,5270,Ustilago maydis,,AB31,smut (corn),monocots,4577,Zea mays (related: maize),,,,,zinc-finger transcription factor,,,,loss of pathogenicity,,yes,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20700446,PubMed,10.1371/journal.ppat.1001035,,joe rg.kaemper@kit.e du,no comments,Kai Heimel,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2628,PHI:2238,,no data found,MUMDB,um10957,,,,Cap1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling,,,,cAMP pathway,reduced virulence,yes,,,,,,,aberrant,,no,,,,,,,gene deletion: full,,,RP,,Not in PubMed,10.1016/j.pmpp.2010.08.002,,sgold@uga.edu,no comments,Johanna E. Takach,2010,,Takach-2010-Identification and c,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2629,PHI:2238,,no data found,MUMDB,um10957,,,,Cap1,,,,,,,5270,Ustilago maydis,,1/2,smut (corn),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling,,,,cAMP pathway,reduced virulence,yes,,,,,,,aberrant,,no,,,,,,,gene deletion: full,,,RP,,Not in PubMed,10.1016/j.pmpp.2010.08.002,,sgold@uga.edu,no comments,Johanna E. Takach,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2630,PHI:2238,,no data found,MUMDB,um10957,,,,Cap1,,,,,,,5270,Ustilago maydis,,2/9,smut (corn),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling,,,,cAMP pathway,reduced virulence,yes,,,,,,,aberrant,,no,,,,,,,gene deletion: full,,,RP,,Not in PubMed,10.1016/j.pmpp.2010.08.002,,sgold@uga.edu,no comments,Johanna E. Takach,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2631,PHI:2239,UniProt,Q4P245,GenBank,um05818,,,,Spe-Sdh,,,,,,,5270,Ustilago maydis,,LV7,smut (corn),monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,seedling,encodes spermidine synthase/saccharopine dehydrogenase,,,,reduced virulence,no,,,,scant and small tumors,,,aberrant,,no,sorbitol; sodium chloride; sodium lauryl sulfate; calcofluor white,sorbitol: CAS:50-70-4; sodium chloride: CAS:7681-52-9; sodium lauryl sulfate: CAS:151-21-3; calcofluor white: CAS:91-44-1,,,,,gene disruption; gene complementation,,,RP,19624748,PubMed,10.1111/j.1567-1364.2009.00539.x,,jruiz@ira.cinvestav.mx,Increased sensitivity to cell wall stressors,Laura Valdés-Santiago,2009,,Valdes-Santiago-2009-Ustilago maydis sper-2670730388,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2632,PHI:2239,UniProt,Q4P245,GenBank,um05818,,,,Spe-Sdh,,,,,,,5270,Ustilago maydis,,LV54,smut (corn),monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,seedling,encodes spermidine synthase/saccharopine dehydrogenase,,,,reduced virulence,no,,,,scant and small tumors,,,aberrant,,no,sorbitol; sodium chloride; sodium lauryl sulfate; calcofluor white,sorbitol: CAS:50-70-4; sodium chloride: CAS:7681-52-9; sodium lauryl sulfate: CAS:151-21-3; calcofluor white: CAS:91-44-1,,,,,gene disruption; gene complementation,,,RP,19624748,PubMed,10.1111/j.1567-1364.2009.00539.x,,jruiz@ira.cinvestav.mx,Increased sensitivity to cell wall stressors,Laura Valdés-Santiago,2009,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2633,PHI:2240,UniProt,Q4PBY9,MUMDB,um02374,,,,Srt1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),,,,leaf,sucrose transporter,,,,reduced virulence,,,,,"only chlorotic lesions, or minute tumors",,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20161717,PubMed,10.1371/journal.pbio.1000303,,joe rg.kaemper@kit.e du (JK); nsauer@biolog ie.uni-erlang en.de (NS),no comments,Ramon Wahl,2010,,Wahl-2010-A Novel High-Affinit,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2634,PHI:2241,,no data found,MUMDB,um10146,,,,Rak1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling; leaf,,,,,reduced virulence,yes,yes,,,chlorosis and rare ligula swellings; no tumors,,,aberrant; reduced,,no,7-diethylamino-4-methylcoumarin; Congo red; sorbitol; sodium chloride,7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0; sorbitol: CAS:50-70-4; sodium chloride: CAS:7681-52-9,,,,,gene deletion: full; gene complementation,,,RP,21815950,PubMed,10.1111/j.1365-2958.2011.07783.x,,kahmann@mpi-marburg.mpg.de,Increased sensitivity to cell wall stressors,Lei Wang,2011,,Wang-2011-A seven-WD40 protein-1781536916,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2635,PHI:2244,UniProt,Q4P8W4,GenBank,um03449.1,,,521,Sep3,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,"GTP-binding proteins involved in multiple cellular functions, including cell division and morphogenesis",,,,unaffected pathogenicity,,,,,,wild type,,aberrant,aberrant,no,sorbitol; caffeine; 7-diethylamino-4-methylcoumarin; chlorpromazine; brefeldin A,sorbitol: CAS:50-70-4; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; chlorpromazine: CAS:50-53-3; brefeldin A: CAS:20350-15-6; caffeine: CAS:58-08-2,,,,,gene deletion: full,,,RP,20885997,PubMed,10.1371/journal.pone.0012933,,jperez@cnb .csic.es,"We found that the temperature-sensitive growth, the cell lysis defect and the morphological defect of the mutants were rescued by 1 M sorbitol, an osmotic stabilizer/Septin deficient cells were more susceptible to cell wall stressors than wild type",Isabel Alvarez-Tabarés,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2636,PHI:2244,UniProt,Q4P8W4,GenBank,um03449.1,,,521,Sep3,,,,,,PHI:2245,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,"GTP-binding proteins involved in multiple cellular functions, including cell division and morphogenesis",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20885997,PubMed,10.1371/journal.pone.0012933,,jperez@cnb .csic.es,"We found that the temperature-sensitive growth, the cell lysis defect and the morphological defect of the mutants were rescued by 1 M sorbitol, an osmotic stabilizer/Septin deficient cells were more susceptible to cell wall stressors than wild type",Isabel Alvarez-Tabarés,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2637,PHI:2246,UniProt,Q4PHC9,GenBank,XM_751538.1,,,521,Aga1,,,,,,,5270,Ustilago maydis,,SG200,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,AGC ser/Thr kinase,,,,loss of pathogenicity,yes,yes,yes,yes,small chlorotic spots,,,aberrant; reduced,,no,7-diethylamino-4-methylcoumarin; Congo red,7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0,,,,,gene deletion: full; gene complementation,,,RP,21143319,PubMed,10.1111/j.1365-2958.2010.07422.x,,kahmann@mpi-marburg.mpg.de,"Compared with SG200, SG200Daga1 displayed slightly enhanced sensitivity towards the cell wall stressors Congo red and calcofluor.",Patrick Berndt,2010,,Berndt-2010-The AGC Ser_Thr kina-2721061268,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2638,PHI:2246,UniProt,Q4PHC9,GenBank,XM_751538.1,,,521,Aga1,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (corn),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,AGC ser/Thr kinase,,,,loss of pathogenicity,yes,yes,yes,yes,small chlorotic spots,,,aberrant; reduced,,no,7-diethylamino-4-methylcoumarin; Congo red,7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0,,,,,gene deletion: full; gene complementation,,,RP,21143319,PubMed,10.1111/j.1365-2958.2010.07422.x,,kahmann@mpi-marburg.mpg.de,"Compared with SG200, SG200Daga1 displayed slightly enhanced sensitivity towards the cell wall stressors Congo red and calcofluor.",Patrick Berndt,2010,,,Batch005,2012-05-21,MC,,,,,,,,,,,,,
,,Record 2639,PHI:2247,UniProt,Q0UDE7,GenBank,EAT82552,,,SN15,Sch1,,,,,,,13684,Parastagonospora nodorum,321614,SN15; Sch1-30,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,short-chain dehydrogenase,,,,unaffected pathogenicity,,,,,lesions,reduced; aberrant,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full,,,AR,18776038,PubMed,10.1128/EC.00237-08,Tan et al. (2008) Eukaryot Cell 7(11):1916-1926,p.solomon@murdoch.edu.au,no comments,Tan et al.,2008,,Tan_2008_EC,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2640,PHI:2248,UniProt,Q1L2E2,GenBank,DQ167577,,,SN15,Als1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,seedling,delta-aminolevulinic acid synthase,,,,reduced virulence,,,,,lesions,,,reduced,wild type; aberrant,no,aminolevulinic acid,CAS:106-60-5,,,,,gene deletion: full,,,AR,16622070,PubMed,10.1099/mic.0.28556-0,,psolomon@murdoch.edu.au,There was no discernable difference in growth observed compared to wild-type when the mutants were grown in the presenc e of Aminolevulinic acid [AL A]. ALA increases mean germ tube length.,Peter S. Solomon,2006,,Solomon_2006_Mic,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2641,PHI:2248,UniProt,Q1L2E2,GenBank,DQ167577,,,SN15,Als1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,delta-aminolevulinic acid synthase,,,,loss of pathogenicity,,,yes,no,lesions,,,reduced,wild type; aberrant,no,aminolevulinic acid,CAS:106-60-5,,,,,gene deletion: full,,,AR,16622070,PubMed,10.1099/mic.0.28556-0,,psolomon@murdoch.edu.au,There was no discernable difference in growth observed compared to wild-type when the mutants were grown in the presenc e of Aminolevulinic acid [AL A]. ALA increases mean germ tube length. Addition of ALA rescues loss of pathogenicity in Detached-leaf pathogenicity assays.,Peter S. Solomon,2006,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2642,PHI:2249,UniProt,Q0U6E8,EMBL,AY547308,,,SN15,Mpd1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),,,,seedling; leaf,mannitol-1-phosphate 5-dehydrogenase,,,,unaffected pathogenicity,,,,,necrotic lesions,reduced,,wild type,wild type,no,sodium chloride; hydrogen peroxide; azoxystrobin,"sodium chloride: CAS:7647-14-5; hydrogen peroxide: CAS:7722-84-1; azoxystrobin: CHEBI:40909, CAS:131860-33-8",,,,,gene deletion: full,,,AR,15720079,PubMed,10.1094/MPMI-18-0110,,roliver@murdoch.edu.au,"The growth rate in liquid media containing sublethal concentrations of NaCl, H2O2, and the fungicide azoxystrobin were unaltered.",Peter S. Solomon,2005,,Solomon_2005_MPMI,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2643,PHI:2250,,no data found,GenBank,AY327542,,,SN15,Gna1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),,,,leaf,,,,,reduced virulence,,,yes,,,reduced,,wild type,,no,sodium chloride; cyclic AMP; cholera toxin,sodium chloride: CAS:7647-14-5; cyclic AMP: CAS:60-92-4; cholera toxin: CAS:9012-63-9,,,,,gene deletion: full,,,AR,15141949,PubMed,10.1094/MPMI.2004.17.5.456,,roliver@murdoch.edu.au,"The growth rate was reduced in Gna1 disrupted mutants compared to the wild type when grown in presence of NaCl; In the presence of cAMP, there was no significant effect on lesion size in GNa1 disrupted mutants or wild type; Lesion size was unaffected in the Gna1 mutant in the presence of cholera toxin. However, in both S. nodorum SN15 and the ectopic strain SNGap17, the lesions were significantly larger in the cholera-toxin-treated samples than were those caused by the untreated samples or those treated with cAMP.",Peter S. Solomon,2004,,Solomon_2004_MPMI,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2644,PHI:2251,,no data found,GenBank,AY576607,,,SN15,Gox1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,seedling; leaf,glyoxalase,,,,unaffected pathogenicity,,,,,necrotic lesions,wild type,,wild type,,no,methyl glyoxal,CAS:78-98-8,,,,,gene deletion: full,,,AR,15205912,PubMed,10.1007/s00294-004-0514-8,,psolomon@murdoch.edu.au,Concentrations of 500 microM methylglyoxal and higher in the growth medium caused a significant reduction in the growth rate of the mutants,Peter S. Solomon,2004,,Solomon_2004_CG,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2645,PHI:2252,,no data found,GenBank,GQ871928,,,4287,Fhk1,,,,,,,5507,Fusarium oxysporum,426428,4287,vascular wilt,eudicots,4082,Solanum peruvianum (related: peruvian tomato),cv. Monica,,,root,histidine kinase,,,,reduced virulence,,,no,,,,,wild type,,no,fludioxonil; iprodione; sodium chloride; potassium chloride; glycerin; menadione; hydrogen peroxide; sodium nitrite,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; sodium chloride: CAS:7647-14-5; potassium chloride: CAS:7447-40-7; glycerin: CAS:56-81-5; menadione: CAS:58-27-5; hydrogen peroxide: CAS:7722-84-1; sodium nitrite: CAS:7632-00-0",,,,,gene deletion: full; gene complementation,,,AR,20447287,PubMed,10.1111/J.1364-3703.2010.00612.X,,ge2ririn@uco.es,"Growth rates of Fhk1 mutant was not affected in presence of fludioxonil or iprodione; colony growth on SM containing 0.8 M sodium chloride, 0.8 M potassium chloride or 1.2 M glycerol was reduced; addition of 10 microg/mL menadione induced drastic growth inhibition in fhk1 deletion mutants; Hydrogen peroxide induced growth inhibition in fhk1 deletion mutants; Sodium nitrite had no significant effect on growth rate in fhk1 deletion mutants",Nicolas Rispail,2010,,Rispail-2010-The two-component hi,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2646,PHI:2253,,no data found,GenBank,AF286533,,,,Fmk1,,,,,,,5507,Fusarium oxysporum,426428,4287,vascular wilt,eudicots,4082,Solanum peruvianum (related: peruvian tomato),cv. Monica,,,root,mitogen-activated protein kinase,,,,reduced virulence,,,yes,,,,,reduced,,no,fludioxonil; iprodione; sodium chloride; potassium chloride; glycerin; menadione; hydrogen peroxide; sodium nitrite,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; sodium chloride: CAS:7647-14-5; potassium chloride: CAS:7447-40-7; glycerin: CAS:56-81-5; menadione: CAS:58-27-5; hydrogen peroxide: CAS:7722-84-1; sodium nitrite: CAS:7632-00-0",,,,,gene deletion: full,,,AR,20447287,PubMed,10.1111/J.1364-3703.2010.00612.X,,ge2ririn@uco.es,"Fmk1 deletion mutant showed a dramatic decrease in growth rate on SM supplemented with 10 m g/mL of fludioxonil or iprodione, compared with SM without fungicide; colony growth on SM containing 0.8 M sodium chloride, 0.8 M potassium chloride or 1.2 M glycerol was reduced; addition of 10 microg/mL menadione induced only moderate growth inhibition in fmk1 deletion mutants; Hydrogen peroxide induced growth inhibition in fmk1 deletion mutants; Sodium nitrite led to a significant decrease in growth rate in fmk1 deletion mutants",Nicolas Rispail,2010,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2647,PHI:2252,,no data found,GenBank,GQ871928,,,4287,Fhk1,,,,,,PHI:2253,5507,Fusarium oxysporum,426428,4287,vascular wilt,eudicots,4082,Solanum peruvianum (related: peruvian tomato),cv. Monica,,,root,histidine kinase,,,,reduced virulence,,,yes,,,,,reduced,,no,fludioxonil; iprodione; sodium chloride; potassium chloride; glycerin; menadione; hydrogen peroxide; sodium nitrite,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; sodium chloride: CAS:7647-14-5; potassium chloride: CAS:7447-40-7; glycerin: CAS:56-81-5; menadione: CAS:58-27-5; hydrogen peroxide: CAS:7722-84-1; sodium nitrite: CAS:7632-00-0",,,,,gene deletion: full; gene complementation,,,AR,20447287,PubMed,10.1111/J.1364-3703.2010.00612.X,,ge2ririn@uco.es,"Growth rates of Fhk1 and Fmk1 double mutanta were not affected in presence of fludioxonil or iprodione; colony growth on SM containing 0.8 M sodium chloride, 0.8 M potassium chloride or 1.2 M glycerol was reduced; addition of 10 microg/mL menadione induced only moderate growth inhibition in fmk1 and fhk1 double deletion mutants; Hydrogen peroxide induced growth inhibition in fmk1 and fhk1 double deletion mutants; Sodium nitrite led to a significant decrease in growth rate in fmk1 and fhk1 double deletion mutants",Nicolas Rispail,2010,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2648,PHI:2253,,no data found,GenBank,AF286533,,,,Fmk1,,,,,,PHI:2252,5507,Fusarium oxysporum,426428,4287,vascular wilt,eudicots,4082,Solanum peruvianum (related: peruvian tomato),cv. Monica,,,root,mitogen-activated protein kinase,,,,reduced virulence,,,yes,,,,,reduced,,no,fludioxonil; iprodione; sodium chloride; potassium chloride; glycerin; menadione; hydrogen peroxide; sodium nitrite,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; sodium chloride: CAS:7647-14-5; potassium chloride: CAS:7447-40-7; glycerin: CAS:56-81-5; menadione: CAS:58-27-5; hydrogen peroxide: CAS:7722-84-1; sodium nitrite: CAS:7632-00-0",,,,,gene deletion: full,,,AR,20447287,PubMed,10.1111/J.1364-3703.2010.00612.X,,ge2ririn@uco.es,"Growth rates of Fhk1 and Fmk1 double mutanta were not affected in presence of fludioxonil or iprodione; colony growth on SM containing 0.8 M sodium chloride, 0.8 M potassium chloride or 1.2 M glycerol was reduced; addition of 10 microg/mL menadione induced only moderate growth inhibition in fmk1 and fhk1 double deletion mutants; Hydrogen peroxide induced growth inhibition in fmk1 and fhk1 double deletion mutants; Sodium nitrite led to a significant decrease in growth rate in fmk1 and fhk1 double deletion mutants",Nicolas Rispail,2010,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2649,PHI:2255,UniProt,Q0U2A0,Broad,SNOG_14274,,,SN15,Abd1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,whole plant,arabitol dehydrogenase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,L-arabinose; xylose,L-arabinose: CAS:5328-37-0; xylose: CAS:58-86-6,,,,,gene deletion: full,,,AR,18796335,PubMed,10.1016/j.fgb.2008.08.006,,psolomon@murdoch.edu.au,No growth when arabinose was the source of carbon; reduced growth when xylose was source of carbon,Rohan G.T. Lowe,2008,,Lowe_2008_FGB,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2650,PHI:2256,UniProt,Q0UA24,Broad,SNOG_11390,,,SN15,Xdh1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,whole plant,xylitol dehydrogenase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,L-arabinose; xylose,L-arabinose: CAS:5328-37-0; xylose: CAS:58-86-6,,,,,gene deletion: full,,,AR,18796335,PubMed,10.1016/j.fgb.2008.08.006,,psolomon@murdoch.edu.au,The xdh1 strains grew at approximately 20% of the wild-type rate on arabinose; reduced growth when xylose was the source of carbon,Rohan G.T. Lowe,2008,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2651,PHI:2255,UniProt,Q0U2A0,Broad,SNOG_14274,,,SN15,Abd1,,,,,,PHI:2256,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,whole plant,arabitol dehydrogenase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,L-arabinose; xylose,L-arabinose: CAS:5328-37-0; xylose: CAS:58-86-6,,,,,gene deletion: full,,,AR,18796335,PubMed,10.1016/j.fgb.2008.08.006,,psolomon@murdoch.edu.au,No growth when arabinose or xylose was the source of carbon,Rohan G.T. Lowe,2008,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2652,PHI:2256,UniProt,Q0UA24,Broad,SNOG_11390,,,SN15,Xdh1,,,,,,PHI:2255,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,whole plant,xylitol dehydrogenase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,L-arabinose; xylose,L-arabinose: CAS:5328-37-0; xylose: CAS:58-86-6,,,,,gene deletion: full,,,AR,18796335,PubMed,10.1016/j.fgb.2008.08.006,,psolomon@murdoch.edu.au,No growth when arabinose or xylose was the source of carbon,Rohan G.T. Lowe,2008,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2653,PHI:2257,UniProt,Q0UHM8,Broad,SNOG_08736,,,SN15,Pbl1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,seedling; leaf,pantothenate-beta-alanine ligase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"beta-alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, ion(1-), (R)-",CAS:20938-62-9,,,,,gene deletion: full,,,AR,22145589,PubMed,10.1111/J.1364-3703.2011.00770.X,,richard.oliver@curtin.edu.au,Addition of pantothenate reversed the growth inhibiton seen in Pbl1 deletion mutants,Simon V. S. Ipcho,2011,,Ipcho_2011_MPP,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2654,PHI:2258,UniProt,G8DNT2,,HQ830035.1,,,ND90Pr,PPT1,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Bowman,,,seedling; leaf,phosphopantetheinyl transferase,,,,reduced virulence,,yes,no,yes,,reduced; aberrant,,reduced; aberrant,wild type,no,lysine; bathophenanthroline disulfonic acid; ferrichrome; hydrogen peroxide,lysine: CAS:56-87-1; bathophenanthroline disulfonic acid: CAS:28061-20-3; ferrichrome: CAS:15630-64-5; hydrogen peroxide: CAS:7722-84-1,,,,,gene deletion: full; gene complementation,,,AR,22023083,PubMed,10.1111/J.1364-3703.2011.00756.X,,shaobin.zhong@ndsu.edu,"Addition of lysine reversed the growth inhibiton seen in PPT1 deletion mutants when grown in lysine deficient medium; PPT1 deletion mutants failed to grow in presence of iron chelator Bathophenanthroline disulfonic acid, which was rescued upon addition of iron-free siderophore ferrichrome; Growth of PPT1 deletion mutants was completely inhibited in presence of hydrogen peroxide",Yueqiang Leng,2012,,Leng-2012-Sfp-type 4'-phosphop,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2655,PHI:2259,UniProt,G8DNT1,,HQ830034.1,,,ND90Pr,AAR1,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Bowman,,,seedling; leaf,alpha-aminoadipate reductase,,,,reduced virulence,,yes,yes,yes,,wild type,,reduced,,no,lysine,lysine: CAS:56-87-1,,,,,gene deletion: full,,,AR,22023083,PubMed,10.1111/J.1364-3703.2011.00756.X,,shaobin.zhong@ndsu.edu,"Addition of lysine reversed the growth inhibiton seen in AAR1 deletion mutants when grown in lysine deficient medium; lysine biosynthesis is required to keep the fungus continuously growing on intact plants, but is not directly involved in the virulence of C. sativus",Yueqiang Leng,2012,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2656,PHI:2260,UniProt,G8DNT0,,HQ830033.1,,,ND90Pr,PKS1,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Bowman,,,seedling,polyketide synthase,,,melanin biosynthesis pathway,unaffected pathogenicity,,,,,,aberrant,,wild type,,no,,,,,,,gene deletion: full,,,AR,22023083,PubMed,10.1111/J.1364-3703.2011.00756.X,,shaobin.zhong@ndsu.edu,no comments,Yueqiang Leng,2012,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2657,PHI:2261,UniProt,G8DNS9,,HQ830032.1,,,ND90Pr,NPS6,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Bowman,,,seedling; leaf,nonribosomal peptide synthetase 6,,,iron metabolism,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,AR,22023083,PubMed,10.1111/J.1364-3703.2011.00756.X,,shaobin.zhong@ndsu.edu,no comments,Yueqiang Leng,2012,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2658,PHI:2262,UniProt,B5G4W2,GenBank,DQ900618,,,,Mrg1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,,,,,unaffected pathogenicity,no,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,18683907,PubMed,10.1002/ps.1632,Li et al. (2008) Pest Manag Sci. 64(12):1294-1302,roliver @murdoch .edu.au,"Senstive to Malayamycin, a new streptomycete antifungal compound at sporulation stage",Wenfeng Li,2008,,Csukai_2008_PMS-0940088576,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2659,PHI:2262,UniProt,B5G4W2,GenBank,DQ900618,,,,Mrg1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,,,,,unaffected pathogenicity,yes,,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,18683907,PubMed,10.1002/ps.1632,Li et al. (2008) Pest Manag Sci. 64(12):1294-1302,roliver @murdoch .edu.au,"More resistant to Malayamycin, a n ew streptomycete antifungal compound",Wenfeng Li,2008,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2660,PHI:2263,UniProt,Q0U086,Broad,SNOG_14941,,,SN15,StuA,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),,,,leaf,cell differentiation; transcription factor,,,,reduced virulence,yes,no,,,lesions,reduced,reduced,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,20495056,PubMed,10.1128/EC.00064-10,,peter.solomon@anu.edu.au,no comments,Simon V. S. IpCho,2010,,IpCho_2010_EC-2097716224,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2661,PHI:2264,UniProt,C5IAW5,GenBank,FJ823644,,,SN15,SnTox3,located on the end of supercontig14,,,,,,13684,Parastagonospora nodorum,,Sn1501,glume blotch,monocots,4564,Triticum (related: wheat),cv. BG220,,,leaf,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,19806176,PubMed,10.1371/journal.ppat.1000581,,timothy. friesen@ars .usda.gov,Induces Disease on Wheat Carrying the Snn3 Gene. Avirulent when the Snn3 gene absent.,Zhaohu i Liu,2009,,Liu_2009_PLoS-0050896384,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2662,PHI:2265,UniProt,Q0UF61,Broad,SNOG_09603,,,SN15,Tps1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,,,,,reduced virulence,,no,no,no,lesions,reduced,,reduced,reduced,no,trehalose; t-butyl-peroxide,trehalose: CAS:6138-23-4; t-butyl-peroxide: CAS:75-91-2,,,,,gene deletion: full; gene complementation,,,RP,19233304,PubMed,10.1016/j.fgb.2009.02.002,Lowe et al. (2009) Fungal Genet Biol. 46(5):381-389,r.oliver@murdoch.edu.au,"Addition of trehalose reinstated the gene deletion effects, but not the same as complementation. The mutants are sensitive to oxidative stress.",Lowe et al.,2009,,Lowe_2009_FGB-0990420736,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2663,PHI:2266,UniProt,F5HHD5,GenBank,AY187281,,,SN15,Ptr2,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,di/tripeptide transport,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,,Not in PubMed,10.1016/j.pmpp.2003.12.003,,oliver@central.murdoch.edu.au,no comments,Peter S. Solomon,2003,,Solomon_2003_PMPP,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2664,PHI:2267,UniProt,Q5J4D6,GenBank,AY508881,,,SN15,Mls1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf; whole plant,malate synthase,,,,loss of pathogenicity,,yes,yes,no,,,,,reduced,no,glucose; sucrose,glucose: CAS:50-99-7; sucrose: CAS:57-50-1,,,,,gene disruption; gene complementation,,,RP,15306011,PubMed,10.1111/j.1365-2958.2004.04178.x,,psolomon@murdoch.edu.au,Addition of glucose and sucrose could re-establish germination in the mutant spores,Peter S. Solomon,2004,,Solomon_2004_MM,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2665,PHI:2268,UniProt,Q2TLM7,GenBank,AY847792,,,SN15,Mak2,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,mitogen activated protein kinase (MAPK),,,MAPK signal transduction pathway,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced; aberrant,,no,,,,,,,gene disruption,,,RP,16028107,PubMed,10.1007/s00294-005-0588-y,,psolomon@murdoch.edu.au,no comments,Peter S. Solomon,2005,,Solomon_2005_CG,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2666,PHI:2269,UniProt,Q32WF7,GenBank,AY788902,,,,Mdh1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,mannitol 2-dehydrogenase,,,,unaffected pathogenicity,,,,,,reduced (on defined medium),,reduced (on mannitol as sole carbon source),,no,,,,,,,gene disruption,,,RP,16859492,PubMed,10.1042/BJ20060891,Solomon et al. (2006) Biochem J. 399(2):231-9,psolomon@murdoch.edu.au,no comments,Peter S. Solomon,2006,,Solomon_2006_Biochem-2131272448,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2667,PHI:2270,UniProt,Q0U6E8,EMBL,AY547308,,,SN15,Mpd1,,,,,,PHI:2269,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,,,,,unaffected pathogenicity,,,,,,reduced,,reduced (on mannitol as sole carbon source growth abolished),,no,,,,,,,gene disruption,,,RP,16859492,PubMed,10.1042/BJ20060891,Solomon et al. (2006) Biochem J. 399(2):231-9,psolomon@murdoch.edu.au,no comments,Peter S. Solomon,2006,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2668,PHI:2269,UniProt,Q32WF7,GenBank,AY788902,,,,Mdh1,,,,,,PHI:2270,13684,Parastagonospora nodorum,321614,SN15,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,mannitol 2-dehydrogenase,,,,unaffected pathogenicity,,,,,,reduced,,reduced (on mannitol as sole carbon source growth abolished),,no,,,,,,,gene disruption,,,RP,16859492,PubMed,10.1042/BJ20060891,Solomon et al. (2006) Biochem J. 399(2):231-9,psolomon@murdoch.edu.au,no comments,Peter S. Solomon,2006,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2669,PHI:2271,UniProt,Q00LS5,,DQ397887,,,,CpkA,,,,,,,13684,Parastagonospora nodorum,,,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,calcium/calmodulin-dependent protein kinase,,,cAMP signalling pathway,unaffected pathogenicity,,,,,,reduced,,reduced,wild type,no,,,,,,,gene disruption; gene complementation,,,RP,17020577,PubMed,10.1111/j.1365-2958.2006.05380.x,,psolomon@murdoch.edu.au,no comments,Peter S. Solomon,2006,,Solomon_2006_MM,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2670,PHI:2272,UniProt,A9Z1V6,,SNU15778.1,,,,CpkB,,,,,,,13684,Parastagonospora nodorum,,,glume blotch,monocots,4564,Triticum (related: wheat),cv. Amery,,,leaf,calcium/calmodulin-dependent protein kinase,,,cAMP signalling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene disruption,,,RP,17020577,PubMed,10.1111/j.1365-2958.2006.05380.x,,psolomon@murdoch.edu.au,no comments,Peter S. Solomon,2006,,,Batch006a,2012-06-21,MC,,,,,,,,,,,,,
,,Record 2671,PHI:2274,UniProt,C6GZ42,,FM945328,,,20.1,Mid1,,,,,,PHI:2275,5111,Claviceps purpurea,5111,20.1Δku70,ergot,monocots,4550,Secale cereale (related: rye),,,,floret; ovary,environmental Ca2+ sensing,,,,loss of pathogenicity,,,,yes,,,,reduced,reduced,no,calcium cation; magnesium cation,calcium cation: CAS:14127-61-8; magnesium cation: CAS:22537-22-0,,,,,gene deletion: full; gene complementation,,,AR,19762439,PubMed,10.1099/mic.0.030825-0,,tudzyns@uni-muenster.de,Growth rate compared to 20.1Delku70 was further reduced by higher Ca2+ concentration. Supplementing the medium with Mg2+ (66 mM) decreased the mean growth rate to about 45 % that of 20.1Delku70,Jorg Bormann,2009,,"Bormann-2009-Deletion of Mid1, a",Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2672,PHI:2275,UniProt,A3KLI8,,AM497781,,,20.1,ku70,,,,,,PHI:2274,5111,Claviceps purpurea,5111,20.1Δku70,ergot,monocots,4550,Secale cereale (related: rye),,,,floret; ovary,environmental Ca2+ sensing,,,,loss of pathogenicity,,,,yes,,,,reduced,reduced,no,calcium cation; magnesium cation,calcium cation: CAS:14127-61-8; magnesium cation: CAS:22537-22-0,,,,,gene deletion: full,,,AR,19762439,PubMed,10.1099/mic.0.030825-0,,tudzyns@uni-muenster.de,Growth rate compared to 20.1Delku70 was further reduced by higher Ca2+ concentration. Supplementing the medium with Mg2+ (66 mM) decreased the mean growth rate to about 45 % that of 20.1Delku70,Jorg Bormann,2009,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2673,PHI:2276,UniProt,B9ZUL0,,,,,,avrLm4,,,,,,,5022,Leptosphaeria maculans,,v23.1.3 × v37.1.4,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),cv. Darmor,,,plant,,,,,effector (plant avirulence determinant),,,,,lesions,reduced,,increased,wild type,no,,,,,,,"sexual cross, sequencing of resistance conferring allele",,,AR,,Not in PubMed,10.1007/s10658-005-2643-4,,yong-ju.h uang@bb src. ac.uk,Avirulent (AvrLm4) or the virulent (avrLm4) allele of the avirulence locus AvrLm4 were compared for infection efficiency among other parameters. Hence Avirulent AvrLm4 has been considered as wildtype and the data provided in this record for the virulent avrLm4 allele is in comparison to AvrLm4 allele,Y.J. Huang,2006,,10.1007_s10658-005-2643-4,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2674,PHI:2276,UniProt,B9ZUL0,,,,,,avrLm4,,,,,,,5022,Leptosphaeria maculans,,v23.1.3 × v37.1.4,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),cv. Eurol,,,plant,,,,,effector (plant avirulence determinant),,,,,lesions,reduced,,increased,wild type,no,,,,,,,"sexual cross, sequencing of resistance conferring allele",,,AR,,Not in PubMed,10.1007/s10658-005-2643-4,,yong-ju.h uang@bb src. ac.uk,Avirulent (AvrLm4) or the virulent (avrLm4) allele of the avirulence locus AvrLm4 were compared for infection efficiency among other parameters. Hence Avirulent AvrLm4 has been considered as wildtype and the data provided in this record for the virulent avrLm4 allele is in comparison to AvrLm4 allele,Y.J. Huang,2006,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2675,PHI:2281,UniProt,Q258K5,GenBank,AM084345,,,,avrLm1,,,,,,,5022,Leptosphaeria maculans,,,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),cv. Eurol,,,leaf; stem,avirulence,,,,effector (plant avirulence determinant),,,,,,,,wild type,wild type,no,,,,,,,"sexual cross, sequencing of resistance conferring allele",,,RP,,Not in PubMed,10.1007/s10658-009-9539-7,,yong-ju.huang@bbsrc.ac.uk,Fitness cost study of two avirulence alleles-Avirulent (AvrLm1) or the virulent (avrLm1) allele of the avirulence locus AvrLm1 were compared for infection efficiency. Hence Avirulent AvrLm1 has been considered as wildtype and the data provided in this record for the virulent avrLm1 allele is in comparison to AvrLm1 allele,Yong-Ju Huang,2010,,10.1007_s10658-009-9539-7,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2676,PHI:2281,UniProt,Q258K5,GenBank,AM084345,,,,avrLm1,,,,,,,5022,Leptosphaeria maculans,,,Phoma stem canker,eudicots,3708,Brassica napus (related: rape),cv. Darmor,,,leaf; stem,avirulence,,,,effector (plant avirulence determinant),,,,,,,,wild type,wild type,no,,,,,,,"sexual cross, sequencing of resistance conferring allele",,,RP,,Not in PubMed,10.1007/s10658-009-9539-7,,yong-ju.huang@bbsrc.ac.uk,Fitness cost study of two avirulence alleles-Avirulent (AvrLm1) or the virulent (avrLm1) allele of the avirulence locus AvrLm1 were compared for infection efficiency. Hence Avirulent AvrLm1 has been considered as wildtype and the data provided in this record for the virulent avrLm1 allele is in comparison to AvrLm1 allele,Yong-Ju Huang,2010,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2677,PHI:2282,UniProt,J9MHC1,,FOXG_02277,,,,MeaB,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,root,bZip protein,,,nitrogen response pathway,increased virulence (hypervirulence),,,no,,,,,reduced,wild type,no,chlorates; N-acetyl-4-fluoro-3-phenyl-DL-alanine,chlorates: CAS:14866-68-3; N-acetyl-4-fluoro-3-phenyl-DL-alanine: CAS:17481-06-0,,,,,gene deletion: full; gene complementation,,,RP,20639450,PubMed,10.1105/tpc.110.075937,,ge2 dipia@uco.es,Increased sensitivity to chlorate; increased resistance to DL- p-fluorophenylalanine,Manuel S. López-Berges,2010,,Lopez-Berges-2010-A nitrogen response-3066920733,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2678,PHI:2283,UniProt,J9MJU9,,FOXG_03165,,,,AreA,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,root,global nitrogen regulator,,,nitrogen response pathway,reduced virulence,,,no,,,,,reduced,reduced,no,sirolimus,sirolimus: CAS:53123-88-9,,,,,gene deletion: full; gene complementation,,,RP,20639450,PubMed,10.1105/tpc.110.075937,,ge2 dipia@uco.es,Cellophane penetration of the deltaareA strain on ammonium was further enhanced by rapamycin,Manuel S. López-Berges,2010,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2679,PHI:2284,UniProt,J9N257,,FOXG_09254,,,,Msb2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,root; seedling,transmembrane protein,,,MAPK signalling,reduced virulence,,yes,yes,,,,,reduced,wild type,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene deletion: partial; gene complementation,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,Perez-Nadales-2011-The Membrane Mucin M-1874651427,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2680,PHI:2284,UniProt,J9N257,,FOXG_09254,,,,Msb2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,root; seedling,transmembrane protein,,,MAPK signalling,reduced virulence,,yes,yes,,,,,reduced,wild type,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene deletion: partial; gene complementation,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2681,PHI:2284,UniProt,J9N257,,FOXG_09254,,,,Msb2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,root; seedling,transmembrane protein,,,MAPK signalling,reduced virulence,,yes,yes,,,,,reduced,wild type,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene deletion: partial; gene complementation,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2682,PHI:2285,UniProt,Q9HGU2,GenBank,AF286533,,,,Fmk1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,root; seedling,transmembrane protein,,,MAPK signalling,loss of pathogenicity,,yes,yes,yes,,,,reduced,aberrant,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene disruption,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2683,PHI:2285,UniProt,Q9HGU2,GenBank,AF286533,,,,Fmk1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,root; seedling,transmembrane protein,,,MAPK signalling,loss of pathogenicity,,yes,yes,yes,,,,reduced,aberrant,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene disruption,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2684,PHI:2285,UniProt,Q9HGU2,GenBank,AF286533,,,,Fmk1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,root; seedling,transmembrane protein,,,MAPK signalling,loss of pathogenicity,,yes,yes,yes,,,,reduced,aberrant,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene disruption,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2685,PHI:2285,UniProt,Q9HGU2,GenBank,AF286533,,,,Fmk1,,,,,,PHI:2284,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,root; seedling,transmembrane protein,,,MAPK signalling,loss of pathogenicity,,yes,yes,yes,,,,reduced,aberrant,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene disruption,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2686,PHI:2285,UniProt,Q9HGU2,GenBank,AF286533,,,,Fmk1,,,,,,PHI:2284,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,root; seedling,transmembrane protein,,,MAPK signalling,loss of pathogenicity,,yes,yes,yes,,,,reduced,aberrant,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene disruption,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2687,PHI:2285,UniProt,Q9HGU2,GenBank,AF286533,,,,Fmk1,,,,,,PHI:2284,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,root; seedling,transmembrane protein,,,MAPK signalling,loss of pathogenicity,,yes,yes,yes,,,,reduced,aberrant,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene disruption,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2688,PHI:2284,UniProt,J9N257,,FOXG_09254,,,,Msb2,,,,,,PHI:2285,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,root; seedling,transmembrane protein,,,MAPK signalling,loss of pathogenicity,,yes,yes,yes,,,,reduced,aberrant,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene disruption,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2689,PHI:2284,UniProt,J9N257,,FOXG_09254,,,,Msb2,,,,,,PHI:2285,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,root; seedling,transmembrane protein,,,MAPK signalling,loss of pathogenicity,,yes,yes,yes,,,,reduced,aberrant,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene disruption,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2690,PHI:2284,UniProt,J9N257,,FOXG_09254,,,,Msb2,,,,,,PHI:2285,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,root; seedling,transmembrane protein,,,MAPK signalling,loss of pathogenicity,,yes,yes,yes,,,,reduced,aberrant,no,Congo red; 7-diethylamino-4-methylcoumarin; sorbitol,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sorbitol: CAS:50-70-4,,,,,gene disruption,,,RP,21441438,PubMed,10.1105/tpc.110.075093,,ge2 dipia@uco.es,"The Deltamsb2 , but not the D fmk1, strains were more sensitive to the cell wall targeting compounds Congo Red (CR) and Calco-fluor White (CFW) than the wild type strain (Figure 2). Addition of 1 M sorbitol partially rescued the growth defect on CR and CFW. Strikingly, a Dfmk1 Dmsb2 double mutant was significantly more sensitive to these compounds than either of the single mutants.",Elena Pérez-Nadales,2011,,,Batch006b,2012-06-04,MC,,,,,,,,,,,,,
,,Record 2691,PHI:2286,,no data found,GenBank,AB07871.1,,,,AbPro1,,,,,,,29001,Alternaria brassicicola,29001,ATCC 96866,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,transcription factor,,,,reduced virulence,,no,no,no,,wild type,,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,19460100,PubMed,10.1111/j.1365-2958.2009.06689.x,,lawrence@vbi.vt.edu,no comments,Yangrae Cho,2009,,Cho-2009-Identification of no-3825246049,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2692,PHI:2287,,no data found,GenBank,AB09132.1,,,,AbSte12,,,,,,,29001,Alternaria brassicicola,29001,ATCC 96866,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,transcription factor,,,,loss of pathogenicity,,yes,yes,no,,reduced,,reduced,aberrant,no,tryptone,tryptones: CAS:73049-73-7,,,,,gene deletion: full; gene complementation,,,RP,19460100,PubMed,10.1111/j.1365-2958.2009.06689.x,,lawrence@vbi.vt.edu,1% Tryptone restores the pathogeneticity of deletion mutants,Yangrae Cho,2009,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2693,PHI:2288,UniProt,Q66WP9,,AY700092.1,,,Abra43,abnik1,,,,,,,29001,Alternaria brassicicola,29001,ATCC 96866,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,histidine kinase,,,,reduced virulence,,no,no,yes,,wild type,,wild type,,no,tryptone; sodium chloride,tryptones: CAS:73049-73-7; sodium chloride: CAS:7647-14-5,,,,,gene deletion: full; gene complementation,,,RP,19460100,PubMed,10.1111/j.1365-2958.2009.06689.x,,lawrence@vbi.vt.edu,"1% Tryptone restores the pathogeneticity of deletion mutants. /Currently available data suggest that the loss of virulence is associated with the mutants' abilities to cope with uncharacterized host defence mechanisms. The growth rates of hyphal tips were similar between delta abnik1 mutants and wild type in the presence of 2% and 4% NaCl. / In contrast, the growth of aerial hyphae and subsequent conidiation were severely affected in the mutants compared with the wild type in the presence of both 2% and 4% NaCl",Yangrae Cho,2009,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2694,PHI:2289,UniProt,B1GVX4,,AM930229,,,B05.10,BcBOA2,,,,,,PHI:2290,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Caruso,,,leaf,polyketide synthases,,,,reduced virulence,,,,,lesions,,,reduced,,no,,,,,,,gene deletion: full,,,RP,21722295,PubMed,10.1111/J.1364-3703.2010.00692.X,,viaud@versailles.inra.fr,no comments,Berengere Dalmais,2011,,Dalmais-2011-The Botrytis cinerea-1358995553,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2695,PHI:2290,UniProt,B1GVX7,,AM930232,,,B05.10,BcBOA6,,,,,,PHI:2289,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Caruso,,,leaf,polyketide synthases,,,,reduced virulence,,,,,lesions,,,reduced,,no,,,,,,,gene deletion: full,,,RP,21722295,PubMed,10.1111/J.1364-3703.2010.00692.X,,viaud@versailles.inra.fr,no comments,Berengere Dalmais,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2696,PHI:2291,UniProt,A6RNZ1,,BC1G_02163.1,,,B05.10,BcSpl1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,phytotoxic activity,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,hypersensitive response and increased necrosis,gene disruption; gene complementation,,,RP,21707620,PubMed,10.1111/j.1469-8137.2011.03802.x,,nbrito@ull.es,no comments,Marcos Frías,2011,,"Frias-2011-BcSpl1, a cerato-pla-0469803361",Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2697,PHI:2291,UniProt,A6RNZ1,,BC1G_02163.1,,,B05.10,BcSpl1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Havana,,,leaf,phytotoxic activity,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,hypersensitive response and increased necrosis,gene disruption; gene complementation,,,RP,21707620,PubMed,10.1111/j.1469-8137.2011.03802.x,,nbrito@ull.es,no comments,Marcos Frías,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2698,PHI:2291,UniProt,A6RNZ1,,BC1G_02163.1,,,B05.10,BcSpl1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,phytotoxic activity,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,hypersensitive response and increased necrosis,gene disruption; gene complementation,,,RP,21707620,PubMed,10.1111/j.1469-8137.2011.03802.x,,nbrito@ull.es,no comments,Marcos Frías,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2699,PHI:2291,UniProt,A6RNZ1,,BC1G_02163.1,,,B05.10,BcSpl1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,,phytotoxic activity,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,hypersensitive response and increased necrosis,gene disruption; gene complementation,,,RP,21707620,PubMed,10.1111/j.1469-8137.2011.03802.x,,nbrito@ull.es,no comments,Marcos Frías,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2700,PHI:2291,UniProt,A6RNZ1,,BC1G_02163.1,,,B05.10,BcSpl1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,,phytotoxic activity,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,hypersensitive response and increased necrosis,gene disruption; gene complementation,,,RP,21707620,PubMed,10.1111/j.1469-8137.2011.03802.x,,nbrito@ull.es,no comments,Marcos Frías,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2701,PHI:2291,UniProt,A6RNZ1,,BC1G_02163.1,,,B05.10,BcSpl1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,13546,Gerbera (no common name found),,,,petal,phytotoxic activity,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,hypersensitive response and increased necrosis,gene disruption; gene complementation,,,RP,21707620,PubMed,10.1111/j.1469-8137.2011.03802.x,,nbrito@ull.es,no comments,Marcos Frías,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2702,PHI:2292,UniProt,B0XVF7,,AFUB_022090,,,CEA10,aoxA,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,mitochondrial respiration,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,,,,,,,gene disruption,,,RP,22443190,PubMed,10.1111/j.1365-2958.2012.08034.x,,rcramer@montana.edu,"Three immunologically distinct murine models of IPA; chemotherapy model, corticosteroid model and CGD models were used",Nora Grahl,2012,,Grahl-2012-Aspergillus fumigatu-1778426209,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2703,PHI:2293,UniProt,B0XTA5,,AFUB_028740,,,CEA10,cycA,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,mitochondrial respiration,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene disruption,,,RP,22443190,PubMed,10.1111/j.1365-2958.2012.08034.x,,rcramer@montana.edu,"Three immunologically distinct murine models of IPA; chemotherapy model, corticosteroid model and CGD models were used",Nora Grahl,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2704,PHI:2294,UniProt,I1RCK7,,FGSG_01326,,,PH-1,FgFRP1,,,,,,,5518,Fusarium graminearum,229533,Z03643,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Bobwhite,,,spike,F-box gene,,,,unaffected pathogenicity,yes,,,,,reduced,reduced,wild type,,no,glucose,glucose: CAS:50-99-7,,,,,gene deletion: full; gene complementation,,,RP,21722294,PubMed,10.1111/J.1364-3703.2010.00689.X,,c.b.michielse@uni-muenster.de,The addition of 1% glucose to the medium restored conidiation to the wild-type level/ The F. graminearum Delta Fgfrp1 mutant is reduced in growth on several mono- and polysugars and on a few amino acids and carboxylic acids. Enhanced growth is observed on two sugar alcohols and two polysugars,Wilfried Jonkers,2011,,Jonkers-2011-The FRP1 F-box gene-3607142753,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2705,PHI:2294,UniProt,I1RCK7,,FGSG_01326,,,PH-1,FgFRP1,,,,,,,5518,Fusarium graminearum,229533,Z03643,Fusarium ear blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Tipple,,,root,F-box gene,,,,reduced virulence,yes,,,,brown spots and lesions,reduced,reduced,wild type,,no,glucose,glucose: CAS:50-99-7,,,,,gene deletion: full; gene complementation,,,RP,21722294,PubMed,10.1111/J.1364-3703.2010.00689.X,,c.b.michielse@uni-muenster.de,The addition of 1% glucose to the medium restored conidiation to the wild-type level,Wilfried Jonkers,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2706,PHI:2295,UniProt,A6SB12,,BC1G_09967,,,B05.10,BcFRP1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,F-box gene,,,,unaffected pathogenicity,yes,,,,,wild type,reduced; aberrant,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21722294,PubMed,10.1111/J.1364-3703.2010.00689.X,,c.b.michielse@uni-muenster.de,"B. cinereaD Bcfrp1 mutants show no growth reduction on any carbon source, but enhanced growth on many, m ainly mono-, di- and trisaccharides, two sugar alcohols and two glucosides.",Wilfried Jonkers,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2707,PHI:2295,UniProt,A6SB12,,BC1G_09967,,,B05.10,BcFRP1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. C32,,,fruit,F-box gene,,,,unaffected pathogenicity,yes,,,,,wild type,reduced; aberrant,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21722294,PubMed,10.1111/J.1364-3703.2010.00689.X,,c.b.michielse@uni-muenster.de,"B. cinereaD Bcfrp1 mutants show no growth reduction on any carbon source, but enhanced growth on many, m ainly mono-, di- and trisaccharides, two sugar alcohols and two glucosides.",Wilfried Jonkers,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2708,PHI:2295,UniProt,A6SB12,,BC1G_09967,,,B05.10,BcFRP1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),cv. Granny Smith,,,fruit,F-box gene,,,,unaffected pathogenicity,yes,,,,,wild type,reduced; aberrant,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21722294,PubMed,10.1111/J.1364-3703.2010.00689.X,,c.b.michielse@uni-muenster.de,"B. cinereaD Bcfrp1 mutants show no growth reduction on any carbon source, but enhanced growth on many, m ainly mono-, di- and trisaccharides, two sugar alcohols and two glucosides.",Wilfried Jonkers,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2709,PHI:2295,UniProt,A6SB12,,BC1G_09967,,,B05.10,BcFRP1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,F-box gene,,,,unaffected pathogenicity,yes,,,,,wild type,reduced; aberrant,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21722294,PubMed,10.1111/J.1364-3703.2010.00689.X,,c.b.michielse@uni-muenster.de,"B. cinereaD Bcfrp1 mutants show no growth reduction on any carbon source, but enhanced growth on many, m ainly mono-, di- and trisaccharides, two sugar alcohols and two glucosides.",Wilfried Jonkers,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2710,PHI:2296,UniProt,B6RIT9,EMBL,ABW87261.1,,,,tmpL,,,,,,,29001,Alternaria brassicicola,29001,ATCC 96866,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,intracellular redox homeostasis,,,,reduced virulence,,no,no,yes,small lesions,wild type; aberrant,,wild type,wild type,no,potassium superoxide; hydrogen peroxide,hydrogen peroxide: CAS:7722-84-1; potassium superoxide: CAS:12030-88-5,,,,,gene deletion: full; gene complementation,,,RP,19893627,PubMed,10.1371/journal.ppat.1000653,,lawrence @vbi.vt.edu,The Ab DtmpL strain showed increased sensitivity to oxidative stress compared with the wild-type.,Kwang-Hyung Kim,2009,,"Kim-2009-TmpL, a Transmembran-0100704865",Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2711,PHI:2297,UniProt,B0YAP6,EMBL,EDP49089.1,,,CEA10,tmpL,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,intracellular redox homeostasis,,,,reduced virulence,,,,,,wild type; aberrant,,wild type,wild type,no,hydrogen peroxide,hydrogen peroxide: CAS:7722-84-1,,,,,gene disruption; gene complementation,,,RP,19893627,PubMed,10.1371/journal.ppat.1000653,,lawrence @vbi.vt.edu,The germlings of the Af DtmpL strain were more sensitive to H2O2 than the wild-type.,Kwang-Hyung Kim,2009,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2712,PHI:2298,UniProt,A6SSN8,,BC1G_15519.1,,,B05.10,BcCdc42,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,GTPase,,,,reduced virulence,,yes,yes,yes,small necrotic lesion,wild type; aberrant,,reduced,reduced; aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,21839848,PubMed,10.1016/j.fgb.2011.07.007,,tudzyns@uni-muenster.de,no comments,Leonie Kokkelink,2011,,Kokkelink-2011-The small GTPase BcC-1409327713,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2713,PHI:2299,UniProt,G4XVB6,EMBL,JF912404,,,70-15,CHS1,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling; leaf,chitin synthase,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,wild type; aberrant,reduced,no,,,,,,,gene deletion: full,,,RP,22346755,PubMed,10.1371/journal.ppat.1002526,,pengyl@ca u.edu.cn,no comments,Ling -An Kong,2012,,Kong-2012-Different Chitin Syn-2449515105,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2714,PHI:2300,UniProt,G4XVC1,EMBL,JF912409,,,70-15,CHS6,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling; leaf,chitin synthase,,,,loss of pathogenicity,,no,yes,yes,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,22346755,PubMed,10.1371/journal.ppat.1002526,,pengyl@ca u.edu.cn,no comments,Ling -An Kong,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2715,PHI:2301,UniProt,B5M4A8,EMBL,EU935590,,,70-15,CHS7,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling; leaf,chitin synthase,,,,reduced virulence,,yes,,yes,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,22346755,PubMed,10.1371/journal.ppat.1002526,,pengyl@ca u.edu.cn,no comments,Ling -An Kong,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2716,PHI:2302,UniProt,G4XVC0,EMBL,JF912408,,,70-15,CHS5,,,,,,PHI:2300,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling; leaf,chitin synthase,,,,loss of pathogenicity,,no,yes,yes,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,22346755,PubMed,10.1371/journal.ppat.1002526,,pengyl@ca u.edu.cn,no comments,Ling -An Kong,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2717,PHI:2300,UniProt,G4XVC1,EMBL,JF912409,,,70-15,CHS6,,,,,,PHI:2302,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Golden Promise,,,seedling; leaf,chitin synthase,,,,loss of pathogenicity,,no,yes,yes,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,22346755,PubMed,10.1371/journal.ppat.1002526,,pengyl@ca u.edu.cn,no comments,Ling -An Kong,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2718,PHI:2299,UniProt,G4XVB6,EMBL,JF912404,,,70-15,CHS1,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,seedling; leaf,chitin synthase,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,wild type; aberrant,reduced,no,,,,,,,gene deletion: full,,,RP,22346755,PubMed,10.1371/journal.ppat.1002526,,pengyl@ca u.edu.cn,no comments,Ling -An Kong,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2719,PHI:2300,UniProt,G4XVC1,EMBL,JF912409,,,70-15,CHS6,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,seedling; leaf,chitin synthase,,,,loss of pathogenicity,,no,yes,yes,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,22346755,PubMed,10.1371/journal.ppat.1002526,,pengyl@ca u.edu.cn,no comments,Ling -An Kong,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2720,PHI:2301,UniProt,B5M4A8,EMBL,EU935590,,,70-15,CHS7,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,seedling; leaf,chitin synthase,,,,reduced virulence,,yes,,yes,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,22346755,PubMed,10.1371/journal.ppat.1002526,,pengyl@ca u.edu.cn,no comments,Ling -An Kong,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2721,PHI:2302,UniProt,G4XVC0,EMBL,JF912408,,,70-15,CHS5,,,,,,PHI:2300,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,seedling; leaf,chitin synthase,,,,loss of pathogenicity,,no,yes,yes,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,22346755,PubMed,10.1371/journal.ppat.1002526,,pengyl@ca u.edu.cn,no comments,Ling -An Kong,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2722,PHI:2300,UniProt,G4XVC1,EMBL,JF912409,,,70-15,CHS6,,,,,,PHI:2302,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,seedling; leaf,chitin synthase,,,,loss of pathogenicity,,no,yes,yes,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,22346755,PubMed,10.1371/journal.ppat.1002526,,pengyl@ca u.edu.cn,no comments,Ling -An Kong,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2723,PHI:2303,UniProt,D2IV71,EMBL,GQ414506,,,,AaFUS3,,,,,,,5599,Alternaria alternata,5599,EV-MIL31,brown spot (Citrus),eudicots,229630,Citrus x tangelo (related: tangelo),,,,leaf,,,,MAPK signaling pathway,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,"glucose; hydrogen peroxide; tert-butyl hydroperoxide; menadione; potassium superoxide; hematoporphyrin; cercosporin; acid red 87; 2-chloro-5-hydroxypyridine; 2,3,5-triiodobenzoic acid (TIBA); dithionitrobenzoic acid (DTNB); rose bengal (RB); pyridoxine; pyridoxal phosphate; diethyl maleate (DEM); 2,6-dichloroisonicotinic acid (INA)","glucose: CAS:50-99-7; hydrogen peroxide: CAS:7722-84-1; tert-butyl hydroperoxide: CAS:75-91-2; menadione: CAS:58-27-5; potassium superoxide: CAS:12030-88-5; hematoporphyrin: CAS:14459-29-1; cercosporin: CAS:35082-49-6, 87; acid red: CAS:17372-87-1; 2-chloro-5-hydroxypyridine: CAS:41288-96-4; 2,3,5-triiodobenzoic acid: CAS:88-82-4; dithionitrobenzoic acid: CAS:69-78-3; rose bengal: CAS:11121-48-5; pyridoxine: CAS:65-23-6; pyridoxal phosphate: CAS:54-47-7; diethyl maleate: CAS:141-05-9; 2,6-dichloroisonicotinic acid: CAS:5398-44-7",,,,,gene disruption; gene complementation,,,RP,20036749,PubMed,10.1016/j.fgb.2009.12.009,,krchung@ufl.edu,"Glucose partially restored growth in null mutants. / AaFUS3 is required for fungal resistance to 2,3,5-triiodobenzoic acid (TIBA), 2-chloro-5- hydroxypyridine (CHP), diethyl maleate (DEM), and many pyridine-containing compounds. Null mutant is moderately senstive to H2O2, KO2 etc.",Ching-Hsuan Lin,2010,,Lin-2010-The FUS3 MAPK signal-0771793761,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2724,PHI:2304,UniProt,B0JFC8,EMBL,CAP74387,,,B05.10,BCFHG1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,NO detoxification,,,,unaffected pathogenicity,,,,,lesions,wild type,,wild type,wild type,no,sodium nitroprusside; hydrogen peroxide,sodium nitroprusside: CAS:13755-38-9; hydrogen peroxide: CAS:7722-84-1,,,,,gene deletion: full,,,RP,20223291,PubMed,10.1016/j.fgb.2010.03.001,,epbenito@usal.es,"The two D Bcfhg1 strains, a.7 and b.16, grouped together in the statistical analysis and displayed a higher sensitivity to nitrosative stress conditions, being their growth reduced 16.9% and 15.3% (after 5 days), respectively, in the presence of 0.5 mM SNP when compared with their growth in the absence of SNP. / These mtuants and wildtype are sensitive to oxidative stress.",Juan Luis Turrion-Gomez,2010,,Luis Turrion-Gomez-2010-The flavohemoglobin,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2725,PHI:2304,UniProt,B0JFC8,EMBL,CAP74387,,,B05.10,BCFHG1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,NO detoxification,,,,unaffected pathogenicity,,,,,lesions,wild type,,wild type,wild type,no,sodium nitroprusside; hydrogen peroxide,sodium nitroprusside: CAS:13755-38-9; hydrogen peroxide: CAS:7722-84-1,,,,,gene deletion: full,,,RP,20223291,PubMed,10.1016/j.fgb.2010.03.001,,epbenito@usal.es,"The two D Bcfhg1 strains, a.7 and b.16, grouped together in the statistical analysis and displayed a higher sensitivity to nitrosative stress conditions, being their growth reduced 16.9% and 15.3% (after 5 days), respectively, in the presence of 0.5 mM SNP when compared with their growth in the absence of SNP. / These mtuants and wildtype are sensitive to oxidative stress.",Juan Luis Turrion-Gomez,2010,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2726,PHI:2304,UniProt,B0JFC8,EMBL,CAP74387,,,B05.10,BCFHG1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,NO detoxification,,,,unaffected pathogenicity,,,,,lesions,wild type,,wild type,wild type,no,sodium nitroprusside; hydrogen peroxide,sodium nitroprusside: CAS:13755-38-9; hydrogen peroxide: CAS:7722-84-1,,,,,gene deletion: full,,,RP,20223291,PubMed,10.1016/j.fgb.2010.03.001,,epbenito@usal.es,"The two D Bcfhg1 strains, a.7 and b.16, grouped together in the statistical analysis and displayed a higher sensitivity to nitrosative stress conditions, being their growth reduced 16.9% and 15.3% (after 5 days), respectively, in the presence of 0.5 mM SNP when compared with their growth in the absence of SNP. / These mtuants and wildtype are sensitive to oxidative stress.",Juan Luis Turrion-Gomez,2010,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2727,PHI:2305,UniProt,Q2LK92,EMBL,ABA25866,,,B05.10,BcFKBP12,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,rapamycin sensitivity,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: partial,,,RP,19116175,PubMed,10.1016/j.fgb.2008.11.011,,geraldine.mey@univ-lyon1.fr,no comments,Heber Gamboa Meléndez,2008,,Melendez-2009-Role of the Botrytis-1191224417,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2728,PHI:2305,UniProt,Q2LK92,EMBL,ABA25866,,,B05.10,BcFKBP12,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3603,Vitis (no common name found),,,,berry,rapamycin sensitivity,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: partial,,,RP,19116175,PubMed,10.1016/j.fgb.2008.11.011,,geraldine.mey@univ-lyon1.fr,no comments,Heber Gamboa Meléndez,2008,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2729,PHI:2305,UniProt,Q2LK92,EMBL,ABA25866,,,B05.10,BcFKBP12,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,rapamycin sensitivity,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: partial,,,RP,19116175,PubMed,10.1016/j.fgb.2008.11.011,,geraldine.mey@univ-lyon1.fr,no comments,Heber Gamboa Meléndez,2008,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2730,PHI:2305,UniProt,Q2LK92,EMBL,ABA25866,,,B05.10,BcFKBP12,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,cotyledon,rapamycin sensitivity,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: partial,,,RP,19116175,PubMed,10.1016/j.fgb.2008.11.011,,geraldine.mey@univ-lyon1.fr,no comments,Heber Gamboa Meléndez,2008,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2731,PHI:2306,UniProt,Q6Q487,GenBank,XM_746454.,,,Af293,clxA,,,,,,,746128,Aspergillus fumigatus,,H237,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,lectin chaperone,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,"1,4-dithiothreitol (DTT)","1,4-dithiothreitol: CAS:3483-12-3",,,,,gene deletion: full; gene complementation,,,RP,22163332,PubMed,10.1371/journal.pone.0028865,,David.Askew@uc. edu,The Delta clxA mutant was growth impaired at temperatures above 42deg C and was hypersensitive to acute ER stress caused by the reducing agent dithiothreitol and unable to grow when transferred to starvation medium.,Margaret V. Powers-Fletcher,2011,,Powers-Fletcher-2011-Impact of the Lectin,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2732,PHI:2307,UniProt,Q2V9X3,,DQ280313,,,FOP-SP2,ftf1,smallest chromosome (1.8 Mb),,,,,,5507,Fusarium oxysporum,251360,f. sp. phaseoli strain FOP-SP2,Fusarium wilt,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blanca Riñón,,,seedling,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption,,,RP,17462924,PubMed,10.1016/j.fgb.2007.03.003,,josediaz@usal.es,no comments,Brisa Ramos,2007,,Ramos-2007-The gene coding for,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2733,PHI:2308,UniProt,A6RI22,,BC1G_00093.1,,,B05.10,BcCRZ1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,zinc finger transcription factor,,,calcineurin pathway,reduced virulence,,,yes,yes,small lesions,reduced,,reduced; aberrant,wild type,no,magnesium cation (mg2+),magnesium cation: CAS:22537-22-0,,,,,gene deletion: full; gene complementation,,,RP,18263765,PubMed,10.1128/EC.00426-07,,tudzynsb@uni-muenster.de,"The addition of Mg2+ restores the growth rate, conidiation, and penetration and improves the cell wall integrity but has no impact on sclerotium formation or hypersensitivity to Ca2 and H2O2.",Julia Schumacher,2008,,Schumacher-2008-Calcineurin-responsi-0201369185,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2734,PHI:2308,UniProt,A6RI22,,BC1G_00093.1,,,B05.10,BcCRZ1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,zinc finger transcription factor,,,calcineurin pathway,reduced virulence,,,yes,yes,small lesions,reduced,,reduced; aberrant,wild type,no,magnesium cation (mg2+),magnesium cation: CAS:22537-22-0,,,,,gene deletion: full; gene complementation,,,RP,18263765,PubMed,10.1128/EC.00426-07,,tudzynsb@uni-muenster.de,"The addition of Mg2+ restores the growth rate, conidiation, and penetration and improves the cell wall integrity but has no impact on sclerotium formation or hypersensitivity to Ca2 and H2O2.",Julia Schumacher,2008,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2735,PHI:2308,UniProt,A6RI22,,BC1G_00093.1,,,B05.10,BcCRZ1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,36596,Prunus armeniaca (related: apricot),,,,fruit,zinc finger transcription factor,,,calcineurin pathway,reduced virulence,,,yes,yes,small lesions,reduced,,reduced; aberrant,wild type,no,magnesium cation (mg2+),magnesium cation: CAS:22537-22-0,,,,,gene deletion: full; gene complementation,,,RP,18263765,PubMed,10.1128/EC.00426-07,,tudzynsb@uni-muenster.de,"The addition of Mg2+ restores the growth rate, conidiation, and penetration and improves the cell wall integrity but has no impact on sclerotium formation or hypersensitivity to Ca2 and H2O2.",Julia Schumacher,2008,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2736,PHI:2309,UniProt,Q9UW03,,AJ006217,,,,BcatrB,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,ABC transporter,,,,reduced virulence,,no,no,yes,lesions,,,,wild type,no,,,,,,,gene deletion: full,,,RP,19154205,PubMed,10.1111/j.1365-313X.2009.03794.x,,henk-jan.schoonbeek@unifr.ch,Indole glucosinolates and camalexin work in concert in plant defence against B. cinerea,Francesca L. Stefanato,2009,,Stefanato-2009-The ABC transporter,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2737,PHI:2310,UniProt,I2DB61,GenBank,JQ665433,,,70wt-r1,VGB,,,,,,,27337,Verticillium dahliae,,70wt-r1,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),race 1,,,root; leaf,,,,G protein-mediat ed signaling,reduced virulence,,,,,,increased,,aberrant,increased,no,,,,,,,gene disruption; gene complementation,,,RP,22387367,PubMed,10.1016/j.fgb.2012.02.005,,aliki@aua.gr,no comments,Aliki K. Tzima,2012,,Tzima-2012-The G protein beta s,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2738,PHI:2310,UniProt,I2DB61,GenBank,JQ665433,,,70wt-r1,VGB,,,,,,,27337,Verticillium dahliae,,70wt-r1,vascular wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Black Beauty,,,root; leaf,,,,G protein-mediat ed signaling,reduced virulence,,,,,,increased,,aberrant,increased,no,,,,,,,gene disruption; gene complementation,,,RP,22387367,PubMed,10.1016/j.fgb.2012.02.005,,aliki@aua.gr,no comments,Aliki K. Tzima,2012,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2739,PHI:2311,UniProt,F8R4Y0,,HM486910,,,BCRC30501,PKS,,,,,,PHI:2312; PHI:2313,5530,Metarhizium anisopliae,,BCRC30501,green muscardine,moths,51655,Plutella xylostella (related: diamondback moth),,,,,dihydroxynaphthalene melanin biosynthesis,,,melanin biosynthesis pathway,increased virulence (hypervirulence),,,,,,reduced,,increased; aberrant,increased,no,,,,,,,functional test in host,,,RP,21571888,PubMed,10.1128/AEM.02033-10,,sst@ntu.edu.tw,no comments,Min N. Tseng,2011,,Tseng-2011-Enhancing the Stress-3070273121,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2740,PHI:2312,UniProt,O93802,,HM486909,,,BCRC30501,THR,,,,,,PHI:2311; PHI:2313,5530,Metarhizium anisopliae,,BCRC30501,green muscardine,moths,51655,Plutella xylostella (related: diamondback moth),,,,,dihydroxynaphthalene melanin biosynthesis,,,melanin biosynthesis pathway,increased virulence (hypervirulence),,,,,,reduced,,increased; aberrant,increased,no,,,,,,,functional test in host,,,RP,21571888,PubMed,10.1128/AEM.02033-10,,sst@ntu.edu.tw,no comments,Min N. Tseng,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2741,PHI:2313,UniProt,F8R4X8,,HM486908,,,BCRC30501,SCD,,,,,,PHI:2311; PHI:2312,5530,Metarhizium anisopliae,,BCRC30501,green muscardine,moths,51655,Plutella xylostella (related: diamondback moth),,,,,dihydroxynaphthalene melanin biosynthesis,,,melanin biosynthesis pathway,increased virulence (hypervirulence),,,,,,reduced,,increased; aberrant,increased,no,,,,,,,functional test in host,,,RP,21571888,PubMed,10.1128/AEM.02033-10,,sst@ntu.edu.tw,no comments,Min N. Tseng,2011,,,Batch007a,2012-06-20,MC,,,,,,,,,,,,,
,,Record 2742,PHI:2314,UniProt,A7E5X4,,SS1G_00699.1,,,1980,Sssod1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,superoxide dismutase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,ditiocarb sodium (DETC); menadione sodium bisulfite anhydrous; potassium oxalate (KOA),ditiocarb sodium: CAS:148-18-5; menadione sodium bisulfite anhydrous: CAS:130-37-0; potassium oxalate: CAS:583-52-8,,,,oxidative burst in adjacent uninfected cells,gene deletion: full; gene complementation,,,RP,,Not in PubMed,10.1016/j.pmpp.2011.12.005,,mbdickman@tamu.edu,DETC mimicked the gene deletion phenotype is dose dependent manner; menadione reduced the growth rate in null mutants; pathogenicity of the superoxide dismutase mutant was mostly restored following supplementation with oxalate.,Selvakumar Veluchamy,2012,,Veluchamy-2012-The CuZn superoxide,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2743,PHI:2314,UniProt,A7E5X4,,SS1G_00699.1,,,1980,Sssod1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,superoxide dismutase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,ditiocarb sodium (DETC); menadione sodium bisulfite anhydrous; potassium oxalate (KOA),ditiocarb sodium: CAS:148-18-5; menadione sodium bisulfite anhydrous: CAS:130-37-0; potassium oxalate: CAS:583-52-8,,,,oxidative burst in adjacent uninfected cells,gene deletion: full; gene complementation,,,RP,,Not in PubMed,10.1016/j.pmpp.2011.12.005,,mbdickman@tamu.edu,DETC mimicked the gene deletion phenotype is dose dependent manner; menadione reduced the growth rate in null mutants; pathogenicity of the superoxide dismutase mutant was mostly restored following supplementation with oxalate.,Selvakumar Veluchamy,2012,,,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2744,PHI:2315,UniProt,G4XKY9,,JF826792,,,,ChLae1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-N,,,leaf,regulate T-toxin biosyn thesis,,,,reduced virulence,yes,,,,,wild type,aberrant,reduced; aberrant,,no,hydrogen peroxide,hydrogen peroxide: CAS:7722-84-1,,,,less chlorosis,gene deletion: full; gene complementation,,,RP,2238387,PubMed,10.1371/journal.ppat.1002542,,bgt1@c ornell.edu,Increased sensitivity to H2O2. Cochliobolus heterostrophus is pathogen anamorph name,Dongl iang Wu,2012,,Wu-2012-ChLae1 and ChVel1 Re-3758139233,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2745,PHI:2316,UniProt,G4XKY8,,JF826791,,,,ChVel1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-N,,,leaf,regulate T-toxin biosyn thesis,,,,reduced virulence,yes (female sterile),,,,,increased,aberrant,reduced; aberrant,,no,hydrogen peroxide,hydrogen peroxide: CAS:7722-84-1,,,,less chlorosis,gene deletion: full; gene complementation,,,RP,2238387,PubMed,10.1371/journal.ppat.1002542,,bgt1@c ornell.edu,Increased sensitivity to H2O2. Cochliobolus heterostrophus is pathogen anamorph name,Dongl iang Wu,2012,,,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2746,PHI:2315,UniProt,G4XKY9,,JF826792,,,,ChLae1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,regulate T-toxin biosyn thesis,,,,reduced virulence,yes,,,,,wild type,aberrant,reduced; aberrant,,no,hydrogen peroxide,hydrogen peroxide: CAS:7722-84-1,,,,less chlorosis,gene deletion: full; gene complementation,,,RP,2238387,PubMed,10.1371/journal.ppat.1002542,,bgt1@c ornell.edu,Increased sensitivity to H2O2. Cochliobolus heterostrophus is pathogen anamorph name,Dongl iang Wu,2012,,,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2747,PHI:2316,UniProt,G4XKY8,,JF826791,,,,ChVel1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,regulate T-toxin biosyn thesis,,,,reduced virulence,yes (female sterile),,,,,increased,aberrant,reduced; aberrant,,no,hydrogen peroxide,hydrogen peroxide: CAS:7722-84-1,,,,less chlorosis,gene deletion: full; gene complementation,,,RP,2238387,PubMed,10.1371/journal.ppat.1002542,,bgt1@c ornell.edu,Increased sensitivity to H2O2. Cochliobolus heterostrophus is pathogen anamorph name,Dongl iang Wu,2012,,,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2748,PHI:2315,UniProt,G4XKY9,,JF826792,,,,ChLae1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-N,,,leaf,regulate T-toxin biosyn thesis,,,,increased virulence (hypervirulence),yes,,,,,reduced,aberrant,increased,,no,,,,,,more chlorosis,altered gene expression / gene regulation: overexpression,,,RP,2238387,PubMed,10.1371/journal.ppat.1002542,,bgt1@c ornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,Dongl iang Wu,2012,,,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2749,PHI:2316,UniProt,G4XKY8,,JF826791,,,,ChVel1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-N,,,leaf,regulate T-toxin biosyn thesis,,,,increased virulence (hypervirulence),yes,,,,,reduced,aberrant,increased,,no,,,,,,more chlorosis,altered gene expression / gene regulation: overexpression,,,RP,2238387,PubMed,10.1371/journal.ppat.1002542,,bgt1@c ornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,Dongl iang Wu,2012,,,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2750,PHI:2315,UniProt,G4XKY9,,JF826792,,,,ChLae1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,regulate T-toxin biosyn thesis,,,,increased virulence (hypervirulence),yes,,,,,reduced,aberrant,increased,,no,,,,,,more chlorosis,altered gene expression / gene regulation: overexpression,,,RP,2238387,PubMed,10.1371/journal.ppat.1002542,,bgt1@c ornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,Dongl iang Wu,2012,,,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2751,PHI:2316,UniProt,G4XKY8,,JF826791,,,,ChVel1,,,,,,,5016,Bipolaris maydis,5016,C4,leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,regulate T-toxin biosyn thesis,,,,increased virulence (hypervirulence),yes,,,,,reduced,aberrant,increased,,no,,,,,,more chlorosis,altered gene expression / gene regulation: overexpression,,,RP,2238387,PubMed,10.1371/journal.ppat.1002542,,bgt1@c ornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,Dongl iang Wu,2012,,,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2752,PHI:2317,UniProt,B0LW64,,EU381116,,,SD-1,aapk1,,,,,,,5599,Alternaria alternata,5599,SD-1,brown spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. K326,,,leaf,cAMP-dependent protein kinase,,,cAMP signalling pathway,reduced virulence,,,,,lesions,,,reduced,,no,,,,,,less chlorosis,gene deletion: full,,,RP,,Not in PubMed,10.1111/j.1439-0434.2010.01751.x,,lidc20@163.com or lidch20@163.com,no comments,Houjuan X u,2011,,Xu-2011-A cAMP-Dependent Pro-1174448481,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2753,PHI:2318,UniProt,D3J127,,GQ414510,,,,AaSLT2,,,,,,,5599,Alternaria alternata,5599,EV-MIL31,,eudicots,229630,Citrus x tangelo (related: tangelo),,,,leaf,mitogen-activated protein (MAP) kinase,,,mitogen-activated protein kinase-mediated signalling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,"7-diethylamino-4-methylcoumarin; Congo red; 2-chloro-5-hydroxypyridine; 2,3,5-triiodobenzoic acid","7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0; 2-chloro-5-hydroxypyridine: CAS:41288-96-4; 2,3,5-triiodobenzoic acid: CAS:88-82-4",,,,,gene deletion: full; gene complementation,,,RP,21726368,PubMed,10.1111/J.1364-3703.2010.00701.X,,krchung@ufl.edu,"Slt2 mutants displayed hypersensitivity to cell wall-degrading enzymes and chemicals such as calcofluor white, Congo red, also to 2-chloro-5-hydroxypyridine and 2,3,5-triiodobenzoic acid",Jonar Ingan Yago,2011,,Yago-2011-The SLT2 mitogen-act-2483071329,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2754,PHI:2319,UniProt,A6S644,,BC1G_07633.1,,,B05.10,bos5,,,,,,,40559,Botrytis cinerea,40559,38B1,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,mitogen-activated protein kinase kinase,,,HOG pathway,loss of pathogenicity,,no,,,,reduced; aberrant,,reduced; aberrant,,no,iprodione,"iprodione: CHEBI:28909, CAS:36734-19-7",,,,,gene deletion: full; gene complementation,,,RP,20595070,PubMed,10.1016/j.fgb.2010.06.002,,zhma@zju.edu.cn,Delta bos5-21 exhibited increased sensitivity to the dicarboximide fungicide iprodione.,Leiyan Yan,2010,,Yan-2010-The mitogen-activate-3540035937,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2755,PHI:2320,UniProt,C0LD25,,FJ693713,,,,RLAP1,,,,,,,5599,Alternaria alternata,5599,HC-2S,leaf spot,eudicots,64884,Citrus jambhiri (related: rough lemon),,,,leaf,,,,AP1 pathway,loss of pathogenicity,,,,,,wild type,,reduced,reduced,no,acetovanillone; diphenyleneiodonium; hydrogen peroxide; tert-butyl hydroperoxide; potassium superoxide; hematoporphyrin,acetovanillone: CAS:498-02-2; diphenyleneiodonium: CAS:244-54-2; hydrogen peroxide: CAS:7722-84-1; tert-butyl hydroperoxide: CAS:75-91-2; potassium superoxide: CAS:12030-88-5; hematoporphyrin: CAS:14459-29-1,,,,,gene deletion: full; gene complementation,,,RP,,Not in PubMed,10.1016/j.pmpp.2009.09.007,,krchung@ufl.edu,"Co-inoculation of the RLAP1 disruption mutant with NADPH oxidase inhibitors like apocynin or DPI helped restore pathogeneticity in mutants. The mutants were hypersensitive to H2O2, KO2, t-BHP and hematoporphyrin.",Siwy Ling Yang,2009,,Yang-2009-Coordinate control o-0033598049,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2756,PHI:2321,UniProt,Q4WR83,,AFUA_1G17190,,,Af293,SidI,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,acyl-CoA ligase,,,triacetylfusarinine C (TAFC) and ergosterol biosynthetic pathways,reduced virulence,,,,,,,,reduced,,no,"1,10-phenanthrolinedisulfonic acid, 4,7-diphenyl-, sodium salt (1:2) (BPS); hydrogen peroxide; lovastatin","1,10-phenanthrolinedisulfonic   acid,   4,7-diphenyl-,  sodium salt (1:2): CAS:52746-49-3; hydrogen peroxide: CAS:7722-84-1; lovastatin: CAS:81739-26-6",,,,,gene deletion: full; gene complementation,,,RP,22106303,PubMed,10.1073/pnas.1106399108,,hubertus.haas@i-med.ac.at,Mutants unable to grow in presence of bathophenanthroline disulfonate (BPS) / More sensitive to H2O2 / increased resistance to lovastatin / murine neutropenic model of invasive pulmonary aspergillosis used.,Sabiha Yasmin,2011,,Yasmin-2012-Mevalonate governs i-1073785441,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2757,PHI:2322,UniProt,Q4WF54,,AFUA_3G03410,,,Af293,SidH,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,anoyl-CoA hydratase,,,triacetylfusarinine C (TAFC) and ergosterol biosynthetic pathways,reduced virulence,,,,,,,,reduced,,no,"1,10-phenanthrolinedisulfonic acid, 4,7-diphenyl-, sodium salt (1:2) (BPS); hydrogen peroxide; lovastatin","1,10-phenanthrolinedisulfonic   acid,   4,7-diphenyl-,  sodium salt (1:2): CAS:52746-49-3; hydrogen peroxide: CAS:7722-84-1; lovastatin: CAS:81739-26-6",,,,,gene deletion: full; gene complementation,,,RP,22106303,PubMed,10.1073/pnas.1106399108,,hubertus.haas@i-med.ac.at,Mutants unable to grow in presence of bathophenanthroline disulfonate (BPS) / More sensitive to H2O2 / increased resistance to lovastatin / murine neutropenic model of invasive pulmonary aspergillosis used.,Sabiha Yasmin,2011,,,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2758,PHI:2323,UniProt,E9F082,,EFY98542.1,,,ARSEF 23,mhk1,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,group III histidine kinase,,,glycerol pathway,reduced virulence,,,,,,increased,,wild type; aberrant (highly pigmented),,no,hydrogen peroxide; menadione; potassium chloride; sodium chloride; glucose; sucrose,hydrogen peroxide: CAS:7722-84-1; menadione: CAS:58-27-5; potassium chloride: CAS:7447-40-7; sodium chloride: CAS:7647-14-5; glucose: CAS:50-99-7; sucrose: CAS:57-50-1,,,,,gene disruption; gene complementation,,,RP,22118192,PubMed,10.1111/j.1462-2920.2011.02643.x,,mgfeng@zju.edu.cn,"Increased tolerance to H2O2, decreased tolerance to menadione, increased tolerance to hyper-osmolarity, increased conidial thermotolerance",Gang Zhou,2012,,Zhou-2012-A Group III histidin-2130750049,Batch007b,2012-06-27,MC,,,,,,,,,,,,,
,,Record 2759,PHI:2324,UniProt,G4N9G2,,MGG_03288.6,,,Guy11,ZIF1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,b-ZIP transcription factor unique to filamentous ascomycetes,,,,reduced virulence,,,,yes,,wild type,defective,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,MU,20795857,PubMed,10.1094/MPMI-06-10-0129,,jinrong@purdue.edu,"mycotoxin.DON.reduced; forms small, empty perithecia",Wang,2011,,,,2012-06-27,MU,,,,,,,,,,,,,
,,Record 2760,PHI:2324,UniProt,G4N9G2,,MGG_03288.6,,,Guy11,ZIF1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4679,Allium cepa (related: onion),,,,bulb,b-ZIP transcription factor unique to filamentous ascomycetes,,,,reduced virulence,,,,yes,,wild type,defective,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,MU,20795857,PubMed,10.1094/MPMI-06-10-0129,,jinrong@purdue.edu,"mycotoxin DON reduced; forms small, empty perithecia; Tissue epidermal cells of bulb scales.",Wang,2011,,,,2012-06-27,MU,,,,,,,,,,,,,
,,Record 2761,PHI:2325,UniProt,I1RM09,,FGSG_04982,,,PH-1,TEP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,tensin-like phosphatase 1,,,phosphatidylinositol pathway,reduced virulence,,,,,,reduced,,,,,,,,,,,gene deletion,,MU,MU,20618707,PubMed,10.1111/J.1364-3703.2010.00626.X,,linghuojiang2@yahoo.com.cn,increased sensitivity to lithium,Zhang,2010,,,,2012-06-27,MU,,,,,,,,,,,,,
,,Record 2762,PHI:2326,UniProt,I1RJS9,,FGSG_04111,,,PH-1,PTC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,type 2C protein phosphatase,,,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,MU,MU,20447276,PubMed,10.1111/j.1364-3703.2009.00598.x,,linghuojiang2@yahoo.com.cn,mycelium growth in response to lithium,Jiang,2010,,,,2012-06-27,MU,,,,,,,,,,,,,
,,Record 2763,PHI:2327,UniProt,P0C431,,FGSG_09612,,,PH-1,HOG1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,,mitogen-activated protein kinase,,,,reduced virulence,,,,,,,aberrant,,,,,,,,,,gene deletion,,MU,MU,21037181,PubMed,10.1128/EC.00150-10,Eukaryot Cell.2010 Dec;9(12):1867-80,bgt1@cornell.edu,,Oide,2010,,,,2012-06-27,MU,,,,,,,,,,,,,
,,Record 2764,PHI:2328,UniProt,I1RIA7,,FGSG_03538,,,PH-1,TRI10,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,,transcriptional regulator,,,trichothecene biosynthesis,reduced virulence,,,,,,,,,,,,,,,,,gene deletion,,MU,MU,19320833,PubMed,10.1111/j.1365-2958.2009.06649.x,,hckist@umn.edu,mycotoxin.DON.in_vitro_reduced,Seong,2009,,,,2012-06-27,MU,,,,,,,,,,,,,
,,Record 2765,PHI:2329,UniProt,A0ST42,,DQ991506,,,,CTB4,,,,,,,29003,Cercospora nicotianae,29003,14,frog-eye leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Burley 21,,,leaf,encodes a putative membrane transporter,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,17250832,PubMed,10.1016/j.febslet.2007.01.011,,krchung@ufl.edu,no comments,Mathias Choquer,2007,,Choquer-2007-Deletion of a MFS tr,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2766,PHI:2330,UniProt,Q7ZA49,,AY184496,,,150-1,Lf pmk1,,,,,,,93591,Lecanicillium fungicola,93591,150-1,dry bubble,basidiomycetes,5341,Agaricus bisporus (related: cultivated mushroom),,,,mushroom,,,,MAPK pathway,unaffected pathogenicity,,,no,,,wild type,,wild type,,no,,,,,,,gene deletion: partial,,,RP,20110303,PubMed,10.1099/mic.0.034439-0,,andy.bailey@bristol.ac.uk,no comments,Patrick D . Collopy,2010,,Collopy-2010-The pmk1-like mitoge,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2767,PHI:2331,UniProt,H9DUR1,,JN616379,,,JR2,Ave1,,,,,,,27337,Verticillium dahliae,1202531,JR2,Verticillium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,avirulence,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22416119,PubMed,10.1073/pnas.1119623109/-/DCSupplemental,,bart.thomma@wur.nl,no comments,Ronnie de Jonge,2011,,de Jonge-2012-Tomato immune recept,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2768,PHI:2331,UniProt,H9DUR1,,JN616379,,,JR2,Ave1,,,,,,,27337,Verticillium dahliae,1202531,JR2,Verticillium wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,avirulence,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,functional test in host,,,RP,22416119,PubMed,10.1073/pnas.1119623109/-/DCSupplemental,,bart.thomma@wur.nl,A. tumefaciens strain GV3101,Ronnie de Jonge,2011,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2769,PHI:2331,UniProt,H9DUR1,,JN616379,,,JR2,Ave1,,,,,,,27337,Verticillium dahliae,1202531,JR2,Verticillium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,avirulence,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,functional test in host,,,RP,22416119,PubMed,10.1073/pnas.1119623109/-/DCSupplemental,,bart.thomma@wur.nl,A. tumefaciens strain GV3101,Ronnie de Jonge,2011,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2770,PHI:2331,UniProt,H9DUR1,,JN616379,,,JR2,Ave1,,,,,,,27337,Verticillium dahliae,1202531,JR2,Verticillium wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,avirulence,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,functional test in host,,,RP,22416119,PubMed,10.1073/pnas.1119623109/-/DCSupplemental,,bart.thomma@wur.nl,A. tumefaciens strain GV3101,Ronnie de Jonge,2011,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2771,PHI:2332,UniProt,A8YPP2,,AM902102,,,LMG 2196,PehA,,,,,,,337,Burkholderia glumae,,AU6208,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Milyang 23,,,panicle,polygalacturonases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,18631177,PubMed,10.1111/j.1574-6941.2008.00516.x,,venturi@icgeb.org,no comments,Giuliano Degrassi,2008,,"Degrassi-2008-Identification, char",Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2772,PHI:2333,UniProt,A8YPP3,,AM902103,,,LMG 2196,PehB,,,,,,,337,Burkholderia glumae,,AU6208,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Milyang 23,,,panicle,polygalacturonases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,18631177,PubMed,10.1111/j.1574-6941.2008.00516.x,,venturi@icgeb.org,no comments,Giuliano Degrassi,2008,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2773,PHI:2334,UniProt,E2GL14,,HM366603,,,B05.10,BcNma,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,apoptosis,,,,reduced virulence,,,,,,,,wild type,wild type,no,caproic acid,CAS:142-62-1,,,,,gene deletion: full; gene complementation,,,RP,21277985,PubMed,10.1016/j.fgb.2011.01.007,,amirsh@ex.tau.ac.il,"Delta bcnma strain showed only a slight reduction in growth, whereas growth of the wild-type and over-expressing strains was delayed by 24 h.",Alin Finkelshtein,2011,,Finkelshtein-2011-Botrytis cinerea BcN,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2774,PHI:2334,UniProt,E2GL14,,HM366603,,,B05.10,BcNma,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,apoptosis,,,,reduced virulence,,,,,,,,wild type,reduced,no,caproic acid,CAS:142-62-1,,,,,altered gene expression / gene regulation: overexpression,,,RP,21277985,PubMed,10.1016/j.fgb.2011.01.007,,amirsh@ex.tau.ac.il,"Delta bcnma strain showed only a slight reduction in growth, whereas growth of the wild-type and over-expressing strains was delayed by 24 h.",Alin Finkelshtein,2011,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2775,PHI:2335,,no data found,GenBank,DQ140394,,,T4,BcPIE3,,,,,,,40559,Botrytis cinerea,40559,T4,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,emopamil binding domain protein,,,,reduced virulence,,,no,yes,lesions,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,18156289,PubMed,10.1128/EC.00159-07,,natassa_g_2000@yahoo.com,no comments,A. Gioti,2008,,Gioti-2008-A Botrytis cinerea e,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2776,PHI:2335,,no data found,GenBank,DQ140394,,,T4,BcPIE3,,,,,,,40559,Botrytis cinerea,40559,T4,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,emopamil binding domain protein,,,,reduced virulence,,,no,yes,lesions,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,18156289,PubMed,10.1128/EC.00159-07,,natassa_g_2000@yahoo.com,no comments,A. Gioti,2008,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2777,PHI:2336,UniProt,O00101,,Y13654,,,BSm300,NIA1,,,,,,,13684,Parastagonospora nodorum,,BS171,glume blotch (wheat),monocots,4564,Triticum (related: wheat),cv. Haven,,,leaf,nitrate reductase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,10328985,PubMed,10.1006/fgbi.1998.1113,Howard et al. (1999) Fungal Genetics and Biology 26(2):152-162,,no comments,Howard et al.,1999,,"Howard-1999-Disruption, replacem",Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2778,PHI:2336,UniProt,O00101,,Y13654,,,BSm300,NIA1,,,,,,,13684,Parastagonospora nodorum,,BS171,glume blotch (wheat),monocots,4564,Triticum (related: wheat),cv. Haven,,,leaf,nitrate reductase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: partial,,,RP,10328985,PubMed,10.1006/fgbi.1998.1113,Howard et al. (1999) Fungal Genetics and Biology 26(2):152-162,,no comments,Howard et al.,1999,,"Howard-1999-Disruption, replacem",Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2779,PHI:2337,UniProt,Q5A4M8,,XM_711630.1,,,SC5314,SUR7,,,,,,,5476,Candida albicans,5476,YJA10,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,"needed for proper localization of actin, morphogenesis, cell wall synthesis, and responding to cell wall stress",,,,reduced virulence,,,,yes,,,,aberrant,,no,"hydrogen peroxide ; menadione; cumene hydroperoxide; diamide; cadmium chloride, hydrate; cercosporamide; copper","hydrogen peroxide: CAS:7722-84-1; menadione: CAS:58-27-5; cumene hydroperoxide: CAS:80-15-9; diamide: CAS:10465-78-8; cadmium   chloride,  hydrate: CAS:7790-78-5; cercosporamide: CAS:131436-22-1; copper: CAS:7440-50-8",,,,,gene deletion: full; gene complementation,,,RP,22202230,PubMed,10.1128/mBio.00254-11,,jkonopka@ms.cc.sunysb.edu,Sur7 deficient cells are sensitive to a broad range of chemicals that increase oxidative damage in cells.,Lois M. Douglas,2011,,mBio-2012-Douglas-,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2780,PHI:2338,UniProt,I2G6S4,Ensembl Genomes,UHOR_01405,,,Uh4875-4,UhCna1,,,,,,,120017,Ustilago hordei,120017,Uh364; Uh365,covered smut,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Odessa,,,seed (spike),cell-wall integrity,,,calcineurin pathway,reduced virulence,yes,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,20977307,PubMed,10.1094/MPMI-09-10-0202,,guus.bakkeren@agr.gc.ca,"Mutants displayed a variety of phe-notypes when applying environmental stress such as sensi-tivity to pH, temperature, H2O2, mono- and divalent cations; and to genotoxic, acid, or oxidative stresses.",José Antonio Cervantes-Chávez,2011,,MPMI-09-10-0202,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2781,PHI:2339,UniProt,I2G5N7,Ensembl Genomes,UHOR_01914,,,Uh4875-4,UhCnb1,,,,,,,120017,Ustilago hordei,120017,Uh364; Uh365,covered smut,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Odessa,,,seed (spike),cell-wall integrity,,,calcineurin pathway,reduced virulence,yes,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,20977307,PubMed,10.1094/MPMI-09-10-0202,,guus.bakkeren@agr.gc.ca,"Mutants displayed a variety of phe-notypes when applying environmental stress such as sensi-tivity to pH, temperature, H2O2, mono- and divalent cations; and to genotoxic, acid, or oxidative stresses.",José Antonio Cervantes-Chávez,2011,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2782,PHI:2340,UniProt,Q9L8R8,,AF196486,,,240B1,aiiA,,,,,,,337,Burkholderia glumae,,SL2376,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),cv. Hopyung,,,seedling; caryopsis,,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,21039666,PubMed,10.1111/j.1472-765X.2010.02940.x,,yckimyc@chonnam.ac.kr,The plasmid bearing the strongly expressed aiiA gene was then introduced into B. glumae SL2376 via triparental mating using the pRK2073 helper plasmid.,J.Y. Park,2010,,Park-2010-AiiA-mediated quorum,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2783,PHI:2340,UniProt,Q9L8R8,,AF196486,,,240B1,aiiA,,,,,,,337,Burkholderia glumae,,SL2376,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),cv. Hopyung,,,seedling; caryopsis,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,21039666,PubMed,10.1111/j.1472-765X.2010.02940.x,,yckimyc@chonnam.ac.kr,The plasmid bearing the strongly expressed aiiA gene was then introduced into B. glumae SL2376 via triparental mating using the pRK2073 helper plasmid.,J.Y. Park,2010,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2784,PHI:2340,UniProt,Q9L8R8,,AF196486,,,240B1,aiiA,,,,,,,337,Burkholderia glumae,,SL2376,bacterial grain rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Hopyung,,,seedling; caryopsis,,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,21039666,PubMed,10.1111/j.1472-765X.2010.02940.x,,yckimyc@chonnam.ac.kr,The plasmid bearing the strongly expressed aii A gene was then introduced into B. glumae SL2376 via triparental mating using the pRK2073 helper plasmid.,J.Y. Park,2010,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2785,PHI:2341,UniProt,Q0E7H5,,AM261028,,,BE9401,BeNEP1,,,,,,,278938,Botrytis elliptica,278938,Be9401,grey mold,monocots,4688,Lilium (no common name found),cv. Stargazer,,,leaf,necrosis and ethylene-inducing protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,20507492,PubMed,10.1111/J.1364-3703.2007.00382.X,,jan.vankan@wur.nl,"Testing the biological activity of heterologously expressed protein in Lily, Maize, Rice, Tobacco, Arabidopsis showed that the protein did not cause any phytotoxicity in Lily, Maize or Rice while inducing strong necrotic symptoms in all tested eudicot plants: Arabidopsis, N. tabacum and N. benthamiana",Staats et al,2007,,Staats-2007-Functional analysis,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2786,PHI:2342,UniProt,Q0E7H7,,AM261029,,,BE9401,BeNEP2,,,,,,,278938,Botrytis elliptica,278938,Be9401,grey mold,monocots,4688,Lilium (no common name found),cv. Stargazer,,,leaf,necrosis and ethylene-inducing protein,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,RP,20507492,PubMed,10.1111/J.1364-3703.2007.00382.X,,jan.vankan@wur.nl,"Testing the biological activity of heterologously expressed protein in Lily, Maize, Rice, Tobacco, Arabidopsis showed that the protein did not cause any phytotoxicity in Lily, Maize or Rice while inducing strong necrotic symptoms in all tested eudicot plants: Arabidopsis, N. tabacum and N. benthamiana",Staats et al,2007,,Staats-2007-Functional analysis,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2787,PHI:2343,UniProt,Q0ZJ79,,DQ415987,,,,Pcipg2,,,,,,,4784,Phytophthora capsici,4784,SD33,Phytophthora blight,eudicots,4072,Capsicum annuum (no common name found),cv. Kexing 3,,,leaf,polygalacturonases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,19422018,PubMed,10.1002/dvg.20530,,zhxg@sdau.edu.cn,no comments,Wen Xiu Sun,2009,,Sun-2009-Functional Analysis,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2788,PHI:2344,UniProt,Q8NID8,,AJ421629,,,race 4,Avr2,,,,,,,5499,Fulvia fulva,,race 5,leaf mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker Cf-0,,,leaf,avirulence,,,,effector (plant avirulence determinant),,,,,,reduced,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,18660430,PubMed,10.1105/tpc.108.059394,,bart.thomma@wur.nl,no comments,van Esse et al.,2008,,van Esse-2008-The Cladosporium ful,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2789,PHI:2344,UniProt,Q8NID8,,AJ421629,,,race 4,Avr2,,,,,,,5499,Fulvia fulva,,race 5,leaf mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,avirulence,,,,effector (plant avirulence determinant),,,,,,increased,,,,no,,,,,,,functional test in host: transient expression,,,RP,18660430,PubMed,10.1105/tpc.108.059394,,bart.thomma@wur.nl,A. tumefaciens strain GV3101,van Esse et al.,2008,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2790,PHI:2344,UniProt,Q8NID8,,AJ421629,,,race 4,Avr2,,,,,,,5499,Fulvia fulva,,race 2,leaf mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,avirulence,,,,effector (plant avirulence determinant),,,,,,increased,,,,no,,,,,,,functional test in host: transient expression,,,RP,18660430,PubMed,10.1105/tpc.108.059394,,bart.thomma@wur.nl,A. tumefaciens strain GV3101,van Esse et al.,2008,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2791,PHI:2345,UniProt,Q2TJF8,,AY862192,,,,FSR1,,,,,,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,fungal virulence and sexual mating,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,18524918,PubMed,10.1099/mic.0.2008/016782-0,,wbshim@tamu.edu,Complementation of the deletion construct with different motif revealed that the coiled-coil structure is essential for virulence in F. verticillioides.,Yoshimi Yamamura,2008,,Yamamura-2008-The coiled-coil prot,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2792,PHI:2346,UniProt,Q7Z8D0,,AY348317,,,,Bbmpk1,,,,,,,176275,Beauveria bassiana,176275,Bb0062,white muscardine,butterflies,7116,Pieris brassicae (related: large cabbage white),,,,larva,mitogen-activated protein kinase,,,MAPK pathway,loss of pathogenicity,,yes,yes,no,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,20139313,PubMed,10.1128/AEM.02246-09,,peiyan3@swu.edu.cn,no comments,Yongjun Zhang,2010,,Zhang-2010-Requirement of a Mit,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2793,PHI:2347,UniProt,Q5TIP4,,DQ105560,,,Naz red bean,PGIP2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana SR1,,,leaf,polygalacturonases,,,,effector (plant avirulence determinant),,,,,,,,,,no,indoleacetic acid (IAA),CAS:87-51-4,,,,,functional test in host,,,RP,18065558,PubMed,10.1104/pp.107.109686,,giulia.delorenzo@uniroma1.it,Auxin reverts the enhanced resistance to fungal infection,Simone Ferrari,2008,,Ferrari-2008-Transgenic expressio,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2794,PHI:2347,UniProt,Q5TIP4,,DQ105560,,,Naz red bean,PGIP2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),PG201 line,,,leaf,polygalacturonases,,,,effector (plant avirulence determinant),,,,,,,,,,no,indoleacetic acid (IAA),CAS:87-51-4,,,,,functional test in host,,,RP,18065558,PubMed,10.1104/pp.107.109686,,giulia.delorenzo@uniroma1.it,Auxin reverts the enhanced resistance to fungal infection,Simone Ferrari,2008,,,Batch008,2012-07-13,MC,,,,,,,,,,,,,
,,Record 2795,PHI:2349,UniProt,G8CYZ6,,FGSG_11955,,,PH-1,FgVe1 (FgVeA),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Bobwhite,,,spike,"fungal development, secondary metabolism and virulence",,,,reduced virulence,,,,,,reduced,,aberrant,,no,,,,,,,gene disruption; gene complementation,,MU,MU,22013911,PubMed,10.1111/J.1364-3703.2011.00755.X,,cbarreau@bordeaux.inra.fr,"aurofusarin biosynthesis: reduced; TRI gene expression: aberrant; hyperbranching of mycelium; mycotoxin.DON.{in_vivo, in_vitro}.(none,reduced)",Merhey,2011,,,,2012-07-13,MU,"Barreau, C.",,,,,,,,,,,,
,,Record 2796,PHI:2349,UniProt,G8CYZ6,,FGSG_11955,,,PH-1,FgVe1 (FgVeA),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Bobwhite,,,spike,"fungal development, secondary metabolism and virulence",,,,reduced virulence,,,,,,reduced,,aberrant,,no,,,,,,,gene disruption; gene complementation,,MU,MU,22140571,PubMed,10.1371/journal.pone.0028291,,zhma@zju.edu.cn,,Jiang,2011,,,,2012-07-13,MU,"Barreau, C.",,,,,,,,,,,,
,,Record 2797,PHI:2350,UniProt,I1RTB7,,FGSG_07418,,,PH-1,MID1,4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,spike,stretch-activated calcium-permeable ion channel,,,,unaffected pathogenicity,,,,,,reduced,aberrant,reduced,,no,,,,,,,gene deletion: full; chemical complementation,,MU,MU,21357477,PubMed,10.1128/EC.00235-10,,trail@msu.edu,MID1 mutant phenotype partially restored with Ca2+,Cavinder,2011,,,,2012-07-13,MU,"Trail, F.",,,,,,,,,,,,
,,Record 2798,PHI:2350,UniProt,I1RTB7,,FGSG_07418,,,PH-1,MID1,4,,,,,PHI:1080,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),,,,spike,stretch-activated calcium-permeable ion channel,,,,unaffected pathogenicity,,,,,,reduced,aberrant,reduced,,no,,,,,,,gene deletion: full; chemical complementation,,MU,MU,21357477,PubMed,10.1128/EC.00235-10,,trail@msu.edu,MID1 mutant phenotype partially restored with Ca2+,Cavinder,2011,,,,2012-07-13,MU,"Trail, F.",,,,,,,,,,,,
,,Record 2799,PHI:2351,UniProt,I1RC32,GenBank,XP_381310,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,arginine methyltransferase,,,,reduced virulence,no,no,,yes,,wild type,wild type,reduced,wild type,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full; gene complementation,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,Increased sensitivity to oxidative and membrane stresses,Guanghui Wang,2012,,Fg_AMT1 arginine-3498774104,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2800,PHI:2351,UniProt,I1RC32,GenBank,XP_381310,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,arginine methyltransferase,,,,reduced virulence,no,no,,yes,,wild type,wild type,reduced,wild type,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full; gene complementation,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,Increased sensitivity to oxidative and membrane stresses,Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2801,PHI:2351,UniProt,I1RC32,GenBank,XP_381310,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,corn silk,arginine methyltransferase,,,,reduced virulence,no,no,,yes,,wild type,wild type,reduced,wild type,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full; gene complementation,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,Increased sensitivity to oxidative and membrane stresses,Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2802,PHI:2352,UniProt,I1S1U7,GenBank,XP_390894,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,arginine methyltransferase,,,,unaffected pathogenicity,no,,,,,wild type,wild type,wild type,,no,H2O2; SDS,H2O2: CAS:7722-84-1,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,"Not senstive to stress responses, like wildtype",Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2803,PHI:2352,UniProt,I1S1U7,GenBank,XP_390894,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,arginine methyltransferase,,,,unaffected pathogenicity,no,,,,,wild type,wild type,wild type,,no,H2O2; SDS,H2O2: CAS:7722-84-1,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,"Not senstive to stress responses, like wildtype",Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2804,PHI:2352,UniProt,I1S1U7,GenBank,XP_390894,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,corn ear,arginine methyltransferase,,,,unaffected pathogenicity,no,,,,,wild type,wild type,wild type,,no,H2O2; SDS,H2O2: CAS:7722-84-1,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,"Not senstive to stress responses, like wildtype",Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2805,PHI:2353,UniProt,I1RC32,GenBank,XP_381310,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT1,,,,,,PHI:2354,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,arginine methyltransferase,,,,reduced virulence,no,no,,yes,,wild type,wild type,reduced,wild type,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,Increased sensitivity to oxidative and membrane stresses,Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2806,PHI:2353,UniProt,I1RC32,GenBank,XP_381310,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT1,,,,,,PHI:2354,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,arginine methyltransferase,,,,reduced virulence,no,no,,yes,,wild type,wild type,reduced,wild type,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,Increased sensitivity to oxidative and membrane stresses,Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2807,PHI:2353,UniProt,I1RC32,GenBank,XP_381310,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT1,,,,,,PHI:2354,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,corn silk,arginine methyltransferase,,,,reduced virulence,no,no,,yes,,wild type,wild type,reduced,wild type,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,Increased sensitivity to oxidative and membrane stresses,Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2808,PHI:2354,UniProt,I1S1U7,GenBank,XP_390894,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT2,,,,,,PHI:2353,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,arginine methyltransferase,,,,reduced virulence,no,no,,yes,,wild type,wild type,reduced,wild type,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,Increased sensitivity to oxidative and membrane stresses,Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2809,PHI:2354,UniProt,I1S1U7,GenBank,XP_390894,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT2,,,,,,PHI:2353,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,arginine methyltransferase,,,,reduced virulence,no,no,,yes,,wild type,wild type,reduced,wild type,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,Increased sensitivity to oxidative and membrane stresses,Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2810,PHI:2354,UniProt,I1S1U7,GenBank,XP_390894,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT2,,,,,,PHI:2353,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,corn silk,arginine methyltransferase,,,,reduced virulence,no,no,,yes,,wild type,wild type,reduced,wild type,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,Increased sensitivity to oxidative and membrane stresses,Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2811,PHI:2355,UniProt,A0A0E0SHR3,EMBL,FGRAMPH1_01T20385,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,arginine methyltransferase,,,,reduced virulence,no,,,,,wild type,wild type,wild type,,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,"Not senstive to stress responses, like wildtype",Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2812,PHI:2355,UniProt,A0A0E0SHR3,EMBL,FGRAMPH1_01T20385,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,arginine methyltransferase,,,,reduced virulence,no,,,,,wild type,wild type,wild type,,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,"Not senstive to stress responses, like wildtype",Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2813,PHI:2355,UniProt,A0A0E0SHR3,EMBL,FGRAMPH1_01T20385,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,AMT4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,corn silk,arginine methyltransferase,,,,reduced virulence,no,,,,,wild type,wild type,wild type,,no,hydrogen peroxide; sodium lauryl sulfate,hydrogen peroxide: CAS:7722-84-1; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full,,,RP,22693618,PubMed,10.1371/journal.pone.0038324,,jinrong@purdue.edu,"Not senstive to stress responses, like wildtype",Guanghui Wang,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2814,PHI:2356,UniProt,G4N178,,MGG_07460,,,70-15,MoHYR1,,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare,,,leaf,plant virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,"more ROS production, stronger defense response",gene deletion: full,,,RP,21971181,PubMed,10.4161/viru.2.6.18007,,ndonof@udel.edu,no comments,Kun Huang,2011,,Huang-2011-Suppression of plant-1300959064,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2815,PHI:2357,UniProt,E2EAF6,,GU566074,,,,CYP52X1,,,,,,,176275,Beauveria bassiana,,ATCC 90517,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,fatty acid hydroxylase activity; cytochrome P450 subfamily,,,,reduced virulence,,,yes,no,,wild type,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,22393051,PubMed,10.1074/jbc.M111.338947,,keyhani@ufl.edu,no comments,Shizhu Zhang,2012,,jbc13477-0394989656,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2816,PHI:2358,UniProt,Q4WZL4,,XM_750896,,,Af293,PLD,,,,,,,746128,Aspergillus fumigatus,,B-5233,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,phospholipase,,,,reduced virulence,,no,yes,,,wild type,,wild type,wild type,no,butyl alcohol; VU0359595; phosphatidic acid,butyl alcohol: CAS:71-36-3; VU0359595: CAS:1246303-14-9,,,,,gene deletion: full; gene complementation,,,RP,22083709,PubMed,10.1128/IAI.05830-11,,hanli@bmi.ac.cn,"Loss of the pld gene attenuated the virulence of A. fumigatus in mice immunosuppressed with hydrocortisone acetate but not with cyclophosphamide. / Conidia pretreated with either 1% 1-butanol or 4 nM mammalian PLD1-specific inhibitor VU0359595 internalized less efficiently into A549 cells than the control group pretreated with PBS. Also, pretreatment with the mammalian PLD2-specific inhibitor VU0285655-1 had no effect on A. fumigatus internalization into A549 cells. / the suppressed internalization was fully rescued in the presence of phosphatidic acid.",Xianping Li,2011,,Li-2012-Disruption of the Ph-2760577112,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2817,PHI:2359,UniProt,Q8TG14,,AAM14606,,,,Bcchs3a,,,,,,,40559,Botrytis cinerea,,Bd90,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,chitin synthase,,,,reduced virulence,,yes,yes,no,necrotic lesions,wild type,,reduced,,no,,,,,,,gene disruption,,,RP,20672878,PubMed,10.1094/MPMI-02-10-0046,,marie-christine.soulie@upmc.fr,no comments,Delphine Arbelet,2010,,MPMI-02-10-0046-1871384920,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2818,PHI:2359,UniProt,Q8TG14,,AAM14606,,,,Bcchs3a,,,,,,,40559,Botrytis cinerea,,Bd90,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),Pad3,,,leaf,chitin synthase,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,,,,,,,gene disruption,,,RP,20672878,PubMed,10.1094/MPMI-02-10-0046,,marie-christine.soulie@upmc.fr,no comments,Delphine Arbelet,2010,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2819,PHI:2359,UniProt,Q8TG14,,AAM14606,,,,Bcchs3a,,,,,,,40559,Botrytis cinerea,,Bd90,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),Pad2,,,leaf,chitin synthase,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,,,,,,,gene disruption,,,RP,20672878,PubMed,10.1094/MPMI-02-10-0046,,marie-christine.soulie@upmc.fr,no comments,Delphine Arbelet,2010,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2820,PHI:2359,UniProt,Q8TG14,,AAM14606,,,,Bcchs3a,,,,,,,40559,Botrytis cinerea,,Bd90,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Contender,,,cotyledon,chitin synthase,,,,reduced virulence,,yes,yes,no,necrotic lesions,wild type,,reduced,,no,,,,,,,gene disruption,,,RP,20672878,PubMed,10.1094/MPMI-02-10-0046,,marie-christine.soulie@upmc.fr,no comments,Delphine Arbelet,2010,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2821,PHI:2359,UniProt,Q8TG14,,AAM14606,,,,Bcchs3a,,,,,,,40559,Botrytis cinerea,,Bd90,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,leaf,chitin synthase,,,,reduced virulence,,yes,yes,no,necrotic lesions,wild type,,reduced,,no,,,,,,,gene disruption,,,RP,20672878,PubMed,10.1094/MPMI-02-10-0046,,marie-christine.soulie@upmc.fr,no comments,Delphine Arbelet,2010,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2822,PHI:2361,UniProt,Q0H744,,DQ182488,,,1980,cna1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia,,,leaf,,,,,reduced virulence,,,,,,,,reduced,increased,no,cyclosporine; tacrolimus; quinic acid; caspofungin,cyclosporine: CAS:59865-13-3; tacrolimus: CAS:104987-11-3; quinic acid: CAS:77-95-2; caspofungin: CAS:162808-62-0,,,,,altered gene expression / gene regulation: silencing,,,RP,16776301,PubMed,10.1094/MPMI-19-0682,,Oded.Yarden@huji.ac.il,Mutant strain grown in the presence of both quinic acid and caspofungin were inhibited over 30% more than the mutant strain grown in the presence of caspofungin alone. / Sclerotial formation was negatively correlated with the concentration of CsA.,A. Harel,2006,,MPMI-19-0682-3180007768,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2823,PHI:2361,UniProt,Q0H744,,DQ182488,,,1980,cna1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf,,,,,reduced virulence,,,,,,,,reduced,increased,no,cyclosporine; tacrolimus; quinic acid; caspofungin,cyclosporine: CAS:59865-13-3; tacrolimus: CAS:104987-11-3; quinic acid: CAS:77-95-2; caspofungin: CAS:162808-62-0,,,,,altered gene expression / gene regulation: silencing,,,RP,16776301,PubMed,10.1094/MPMI-19-0682,,Oded.Yarden@huji.ac.il,Mutant strain grown in the presence of both quinic acid and caspofungin were inhibited over 30% more than the mutant strain grown in the presence of caspofungin alone. / Sclerotial formation was negatively correlated with the concentration of CsA.,A. Harel,2006,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2824,PHI:2362,UniProt,A8QJI7,,EF057395,,,,XlnR,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Vemar,,,root; stem,zinc-finger transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,17722701,PubMed,10.1094/MPMI-20-8-0977,,ge1hedic@uco.e,no comments,Fernando Calero-Nieto,2007,,MPMI-20-8-0977-3951759704,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2825,PHI:2363,UniProt,Q96X32,,AAK49432,,,1/2,Ubc2,,,,,,,5270,Ustilago maydis,,15/7,smut (maize),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling; leaf,adaptor protein,,,MAPK signaling pathway,loss of pathogenicity,yes,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,18052888,PubMed,10.1094/MPMI-21-1-0110,,sgold@uga.edu,no comments,Steven J. Klosterman,2008,,MPMI-21-1-0110-0965415512,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2826,PHI:2364,UniProt,O93976,,AJ012668,,,,tom1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,root,tomatinase,,,,reduced virulence,,,,,,,,reduced,,no,alpha-tomatine,tomatine: CAS:17406-45-0,,,,,gene disruption,,,RP,18624637,PubMed,10.1094/MPMI-21-6-0728,,ge2rurom@uco.es,no comments,Yolanda Pareja-Jaime,2008,,MPMI-21-6-0728-2022380120,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2827,PHI:2364,UniProt,O93976,,AJ012668,,,,tom1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,root,tomatinase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,alpha-tomatine,alpha-tomatine: CAS:17406-45-0,,,,,altered gene expression / gene regulation: overexpression,,,RP,18624637,PubMed,10.1094/MPMI-21-6-0728,,ge2rurom@uco.es,no comments,Yolanda Pareja-Jaime,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2828,PHI:2365,UniProt,Q4W6D3,,AB208438,,,HITO7711,Hog1,,,,,,,5016,Bipolaris maydis,,C4; C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,,MAP kinases,,,MAPK signaling pathway,reduced virulence,yes,yes,,,,increased,,wild type; aberrant,,no,potassium chloride; sorbitol; menadione,potassium chloride: CAS:7447-40-7; sorbitol: CAS:50-70-4; menadione: CAS:58-27-5,,,,,gene deletion: full,,,RP,18473669,PubMed,10.1094/MPMI-21-6-0769,,horwitz@tx.technion.ac.il,Hog1 mutants are the most sensitive to stressors while Mps1 mutants are more resistant. Cochliobolus heterostrophus is pathogen anamorph name,Aeid Igbaria,2008,,MPMI-21-6-0769-3582661208,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2829,PHI:2366,UniProt,Q9UVN7,,AF178977,,,C4,Chk1,,,,,,,5016,Bipolaris maydis,,C4; C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,,MAP kinases,,,MAPK signaling pathway,reduced virulence,no,yes,,,,reduced,,wild type,,no,potassium chloride; sorbitol; menadione,potassium chloride: CAS:7447-40-7; sorbitol: CAS:50-70-4; menadione: CAS:58-27-5,,,,,gene deletion: full,,,RP,18473669,PubMed,10.1094/MPMI-21-6-0769,,horwitz@tx.technion.ac.il,Hog1 mutants are the most sensitive to stressors while Mps1 mutants are more resistant. Cochliobolus heterostrophus is pathogen anamorph name,Aeid Igbaria,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2830,PHI:2367,UniProt,A3QYW5,,EF014908,,,,Mps1,,,,,,,5016,Bipolaris maydis,,C4; C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,,MAP kinases,,,MAPK signaling pathway,reduced virulence,yes,no,,,,reduced,,aberrant,wild type,no,potassium chloride; sorbitol; menadione,potassium chloride: CAS:7447-40-7; sorbitol: CAS:50-70-4; menadione: CAS:58-27-5,,,,,gene deletion: full,,,RP,18473669,PubMed,10.1094/MPMI-21-6-0769,,horwitz@tx.technion.ac.il,Hog1 mutants are the most sensitive to stressors while Mps1 mutants are more resistant. Cochliobolus heterostrophus is pathogen anamorph name,Aeid Igbaria,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2831,PHI:2365,UniProt,Q4W6D3,,AB208438,,,HITO7711,Hog1,,,,,,PHI:2367,5016,Bipolaris maydis,,C4; C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,,MAP kinases,,,MAPK signaling pathway,reduced virulence,,,,,,,,aberrant,,no,potassium chloride; sorbitol; menadione,potassium chloride: CAS:7447-40-7; sorbitol: CAS:50-70-4; menadione: CAS:58-27-5,,,,,gene deletion: full,,,RP,18473669,PubMed,10.1094/MPMI-21-6-0769,,horwitz@tx.technion.ac.il,Mps1 mutation in the hog1 background improved resistance to oxidative stresses. Cochliobolus heterostrophus is pathogen anamorph name,Aeid Igbaria,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2832,PHI:2367,UniProt,A3QYW5,,EF014908,,,,Mps1,,,,,,PHI:2365,5016,Bipolaris maydis,,C4; C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,,MAP kinases,,,MAPK signaling pathway,reduced virulence,,,,,,,,aberrant,wild type,no,potassium chloride; sorbitol; menadione,potassium chloride: CAS:7447-40-7; sorbitol: CAS:50-70-4; menadione: CAS:58-27-5,,,,,gene deletion: full,,,RP,18473669,PubMed,10.1094/MPMI-21-6-0769,,horwitz@tx.technion.ac.il,Mps1 mutation in the hog1 background improved resistance to oxidative stresses. Cochliobolus heterostrophus is pathogen anamorph name,Aeid Igbaria,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2833,PHI:2368,UniProt,Q9P880,,AJ276473,,,SAS 56,bac,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,yes,,yes,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,MPMI-21-11-1443-4119532120,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2834,PHI:2369,UniProt,A6S414,,AM948967,,,B05.10,bcpka2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,cAMP pathway catalytic subunit,,,cAMP signaling pathway,unaffected pathogenicity,,yes,,no,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2835,PHI:2370,UniProt,C0H5W3,,AM948966,,,B05.10,bcpka1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,cAMP pathway catalytic subunit,,,cAMP signaling pathway,reduced virulence,,yes,,,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2836,PHI:2371,UniProt,C0H5W5,,AM948968,,,B05.10,bcpkaR,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,cAMP pathway catalytic subunit,,,cAMP signaling pathway,reduced virulence,,yes,,,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2837,PHI:2372,UniProt,A6RUJ6,,BC1G_04437.1,,,B05.10,bcras2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,cAMP pathway catalytic subunit,,,cAMP signaling pathway,reduced virulence,,no,,,,,,reduced,reduced,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2838,PHI:2368,UniProt,Q9P880,,AJ276473,,,SAS 56,bac,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun NN,,,leaf,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,yes,,yes,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2839,PHI:2369,UniProt,A6S414,,AM948967,,,B05.10,bcpka2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun NN,,,leaf,cAMP pathway catalytic subunit,,,cAMP signaling pathway,unaffected pathogenicity,,yes,,no,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2840,PHI:2370,UniProt,C0H5W3,,AM948966,,,B05.10,bcpka1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun NN,,,leaf,cAMP pathway catalytic subunit,,,cAMP signaling pathway,reduced virulence,,yes,,,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2841,PHI:2371,UniProt,C0H5W5,,AM948968,,,B05.10,bcpkaR,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun NN,,,leaf,cAMP pathway catalytic subunit,,,cAMP signaling pathway,reduced virulence,,yes,,,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2842,PHI:2372,UniProt,A6RUJ6,,BC1G_04437.1,,,B05.10,bcras2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun NN,,,leaf,cAMP pathway catalytic subunit,,,cAMP signaling pathway,reduced virulence,,no,,,,,,reduced,reduced,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2843,PHI:2368,UniProt,Q9P880,,AJ276473,,,SAS 56,bac,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,yes,,yes,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2844,PHI:2369,UniProt,A6S414,,AM948967,,,B05.10,bcpka2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,cAMP pathway catalytic subunit,,,cAMP signaling pathway,unaffected pathogenicity,,yes,,no,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2845,PHI:2370,UniProt,C0H5W3,,AM948966,,,B05.10,bcpka1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,cAMP pathway catalytic subunit,,,cAMP signaling pathway,reduced virulence,,yes,,,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2846,PHI:2371,UniProt,C0H5W5,,AM948968,,,B05.10,bcpkaR,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,cAMP pathway catalytic subunit,,,cAMP signaling pathway,reduced virulence,,yes,,,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2847,PHI:2372,UniProt,A6RUJ6,,BC1G_04437.1,,,B05.10,bcras2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,cAMP pathway catalytic subunit,,,cAMP signaling pathway,reduced virulence,,no,,,,,,reduced,reduced,no,,,,,,,gene deletion: full,,,RP,18842094,PubMed,10.1094/MPMI-21-11-1443,,tudzynsb@uni-muenster.de,no comments,Julia Schumacher,2008,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2848,PHI:2373,UniProt,B9V258,,FJ376607,,,,YAP1,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot (Citrus),eudicots,229630,Citrus x tangelo (related: tangelo),,,,leaf,oxidative stress tolerance,,,,loss of pathogenicity,,yes,yes,yes,,,,reduced,wild type,no,apocynin (hydroxy-3-methoxyacetophenone); di-phenylene iodonium (DPI),apocynin (hydroxy-3-methoxyacetophenone): CAS:498-02-2; di-phenylene iodonium (DPI): CAS:244-54-2,,,,,gene disruption; gene complementation,,,RP,19589070,PubMed,10.1094/MPMI-22-8-0942,,krchung@ufl.edu,NADPH oxidase inhibitors only partially re-stored virulence of the AaAP1 null mutant.,Ching-Hsuan Lin,2009,,MPMI-22-8-0942-0596317016,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2849,PHI:2374,UniProt,D2T177,,FM957543,,,B05.10,Bap1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,H2O2; menadione,H2O2: CAS:7722-84-1; menadione: CAS:58-27-5,,,,,gene disruption; gene complementation,,,RP,19589074,PubMed,10.1094/MPMI-22-8-0987,,tudzyns@uni-muenster.de,Mutants more sensitive to ROS,Nora Temme,2009,,MPMI-22-8-0987-1653281624,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2850,PHI:2374,UniProt,D2T177,,FM957543,,,B05.10,Bap1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,H2O2; menadione,H2O2: CAS:7722-84-1; menadione: CAS:58-27-5,,,,,gene disruption; gene complementation,,,RP,19589074,PubMed,10.1094/MPMI-22-8-0987,,tudzyns@uni-muenster.de,Mutants more sensitive to ROS,Nora Temme,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2851,PHI:2374,UniProt,D2T177,,FM957543,,,B05.10,Bap1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),cv. Holsteiner Cox,,,fruit,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,H2O2; menadione,H2O2: CAS:7722-84-1; menadione: CAS:58-27-5,,,,,gene disruption; gene complementation,,,RP,19589074,PubMed,10.1094/MPMI-22-8-0987,,tudzyns@uni-muenster.de,Mutants more sensitive to ROS,Nora Temme,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2852,PHI:2374,UniProt,D2T177,,FM957543,,,B05.10,Bap1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,transcription factor,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,H2O2; menadione,H2O2: CAS:7722-84-1; menadione: CAS:58-27-5,,,,,gene disruption; gene complementation,,,RP,19589074,PubMed,10.1094/MPMI-22-8-0987,,tudzyns@uni-muenster.de,Mutants more sensitive to ROS,Nora Temme,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2853,PHI:2375,UniProt,D2E9W6,,FJ977165,,,MUCL 202097,DEP1,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,MPMI-22-10-1258-0227218520,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2854,PHI:2376,UniProt,D2E9W7,,FJ977165,,,MUCL 202097,DEP2,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2855,PHI:2377,UniProt,D2E9W8,,FJ977165,,,MUCL 202097,DEP3,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2856,PHI:2378,UniProt,D2E9W9,,FJ977165,,,MUCL 202097,DEP4,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2857,PHI:2379,UniProt,D2E9X0,,FJ977165,,,MUCL 202097,DEP5,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2858,PHI:2380,UniProt,D2E9X1,,FJ977165,,,MUCL 202097,DEP6,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2859,PHI:2375,UniProt,D2E9W6,,FJ977165,,,MUCL 202097,DEP1,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2860,PHI:2376,UniProt,D2E9W7,,FJ977165,,,MUCL 202097,DEP2,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2861,PHI:2377,UniProt,D2E9W8,,FJ977165,,,MUCL 202097,DEP3,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2862,PHI:2378,UniProt,D2E9W9,,FJ977165,,,MUCL 202097,DEP4,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2863,PHI:2379,UniProt,D2E9X0,,FJ977165,,,MUCL 202097,DEP5,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2864,PHI:2380,UniProt,D2E9X1,,FJ977165,,,MUCL 202097,DEP6,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2865,PHI:2375,UniProt,D2E9W6,,FJ977165,,,MUCL 202097,DEP1,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),Pad3,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2866,PHI:2376,UniProt,D2E9W7,,FJ977165,,,MUCL 202097,DEP2,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),Pad3,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2867,PHI:2377,UniProt,D2E9W8,,FJ977165,,,MUCL 202097,DEP3,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),Pad3,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2868,PHI:2378,UniProt,D2E9W9,,FJ977165,,,MUCL 202097,DEP4,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),Pad3,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2869,PHI:2379,UniProt,D2E9X0,,FJ977165,,,MUCL 202097,DEP5,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),Pad3,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2870,PHI:2380,UniProt,D2E9X1,,FJ977165,,,MUCL 202097,DEP6,,,,,,,29001,Alternaria brassicicola,,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),Pad3,,,leaf,histone deacetylase inhibitor,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,19737099,PubMed,10.1094/MPMI-22-10-1258,,lawrence@vbi.vt.edu,no comments,Wanessa D. Wight,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2871,PHI:2381,UniProt,Q4PG27,,AY271263,,,,Ucn1,,,,,,,5270,Ustilago maydis,,1/2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Truckers Favorite,,,seedling,protein phosphatase,,,cAMP signaling pathway,loss of pathogenicity,,,,,"chlorotic lesion, no tumors",,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,19737102,PubMed,10.1094/MPMI-22-10-1293,,sgold@uga.edu,no comments,John D. Egan,2009,,MPMI-22-10-1293-1015747672,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2872,PHI:2381,UniProt,Q4PG27,,AY271263,,,,Ucn1,,,,,,,5270,Ustilago maydis,,SG200,smut (maize),monocots,4577,Zea mays (related: maize),cv. Truckers Favorite,,,seedling,protein phosphatase,,,cAMP signaling pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,19737102,PubMed,10.1094/MPMI-22-10-1293,,sgold@uga.edu,no comments,John D. Egan,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2873,PHI:2382,UniProt,Q6QIY0,,AY538590,,,,Upa2,,,,,,,5270,Ustilago maydis,,SG200,smut (maize),monocots,4577,Zea mays (related: maize),cv. Truckers Favorite,,,seedling,protein phosphatase,,,cAMP signaling pathway,unaffected pathogenicity,,,,,,,,,,yes,,,,,,,gene disruption,,,RP,19737102,PubMed,10.1094/MPMI-22-10-1293,,sgold@uga.edu,No haploid hygromycin-resistant progeny were obtained on crossing thus suggesting again that the gene disruption is lethal,John D. Egan,2009,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2874,PHI:2383,UniProt,Q2VF46,,DQ173196,,,,MfCUT1,,,,,,,38448,Monilinia fructicola,,MUK-1,brown rot,eudicots,3755,Prunus dulcis (related: almond),,,,petal,cutinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,20064061,PubMed,10.1094/MPMI-23-2-0176,,rmbostock@ucdavis.edu,Agrobacterium A2388,Miin-Huey Lee,2010,,MPMI-23-2-0176-1535841368,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2875,PHI:2383,UniProt,Q2VF46,,DQ173196,,,,MfCUT1,,,,,,,38448,Monilinia fructicola,,MUK-1,brown rot,eudicots,3760,Prunus persica (related: peach),var. nucipersica (nectarine),,,petal,cutinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,20064061,PubMed,10.1094/MPMI-23-2-0176,,rmbostock@ucdavis.edu,Agrobacterium A2388,Miin-Huey Lee,2010,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2876,PHI:2383,UniProt,Q2VF46,,DQ173196,,,,MfCUT1,,,,,,,38448,Monilinia fructicola,,MUK-1,brown rot,eudicots,3760,Prunus persica (related: peach),,,,petal,cutinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,20064061,PubMed,10.1094/MPMI-23-2-0176,,rmbostock@ucdavis.edu,Agrobacterium A2388,Miin-Huey Lee,2010,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2877,PHI:2383,UniProt,Q2VF46,,DQ173196,,,,MfCUT1,,,,,,,38448,Monilinia fructicola,,MUK-1,brown rot,eudicots,42229,Prunus avium (related: sweet cherry),,,,petal,cutinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,20064061,PubMed,10.1094/MPMI-23-2-0176,,rmbostock@ucdavis.edu,Agrobacterium A2388,Miin-Huey Lee,2010,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2878,PHI:2384,UniProt,Q4P4C1,,UM15042,,,,Ust1,,,,,,,5270,Ustilago maydis,,1/2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling,transcription factor,,,,reduced virulence,yes,no,no,yes,,aberrant,,aberrant,,no,,,,,,,gene deletion: full,,,RP,20064064,PubMed,10.1094/MPMI-23-2-0211,,sgold@uga.edu,no comments,María D. García-Pedrajas,2010,,MPMI-23-2-0211-2592805976,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2879,PHI:2384,UniProt,Q4P4C1,,UM15042,,,,Ust1,,,,,,,5270,Ustilago maydis,,d132,smut (maize),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling,transcription factor,,,,reduced virulence,yes,no,no,yes,,aberrant; reduced,,aberrant,,no,,,,,,,gene deletion: full,,,RP,20064064,PubMed,10.1094/MPMI-23-2-0211,,sgold@uga.edu,no comments,María D. García-Pedrajas,2010,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2880,PHI:2385,UniProt,I1RTN5,,FGSG_07546.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,MYT2,,,,,,,5518,Fusarium graminearum,229533,Z-3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,putative transcription factor,,,,reduced virulence,no,,,,,wild type,increased,increased,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,22649560,PubMed,10.1371/journal.pone.0037859,,lee2443@snu.ac.k r,no comments,Yang Lin,2012,,MYT2_perithecia-3901428824,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2881,PHI:2385,UniProt,I1RTN5,,FGSG_07546.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,MYT2,,,,,,,5518,Fusarium graminearum,229533,Z-3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,putative transcription factor,,,,reduced virulence,no,,,,,reduced,reduced,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,22649560,PubMed,10.1371/journal.pone.0037859,,lee2443@snu.ac.k r,no comments,Yang Lin,2012,,,Batch009,2012-07-31,MC,,,,,,,,,,,,,
,,Record 2882,PHI:2386,UniProt,A0A098E0Z2,EMBL,FGRAMPH1_01T19345,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,ACL1,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,adenosine triphosphate (ATP) citrate lyase,,,,loss of pathogenicity,yes,,,,,reduced,reduced,reduced,,no,potassium acetate,CAS:4251-29-0,,,,,gene deletion: full; gene complementation,,,RP,21237280,PubMed,10.1016/j.fgb.2011.01.002,,lee2443@snu.ac.kr,no comments,Hokyoung Son,2011,,acl,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2883,PHI:2387,UniProt,I1RPR1,,FGSG_06039.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,ACL2,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,adenosine triphosphate (ATP) citrate lyase,,,,loss of pathogenicity,yes,,,,,reduced,reduced,reduced,,no,potassium acetate,CAS:4251-29-0,,,,,gene deletion: full; gene complementation,,,RP,21237280,PubMed,10.1016/j.fgb.2011.01.002,,lee2443@snu.ac.kr,no comments,Hokyoung Son,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2884,PHI:2386,UniProt,A0A098E0Z2,EMBL,FGRAMPH1_01T19345,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,ACL1,,,,,,PHI:2387,5518,Fusarium graminearum,449239,GZ3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,adenosine triphosphate (ATP) citrate lyase,,,,loss of pathogenicity,yes,,,,,reduced,reduced,reduced,,no,potassium acetate,CAS:4251-29-0,,,,,gene deletion: full; gene complementation,,,RP,21237280,PubMed,10.1016/j.fgb.2011.01.002,,lee2443@snu.ac.kr,no comments,Hokyoung Son,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2885,PHI:2387,UniProt,I1RPR1,,FGSG_06039.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,ACL2,,,,,,PHI:2386,5518,Fusarium graminearum,449239,GZ3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,adenosine triphosphate (ATP) citrate lyase,,,,loss of pathogenicity,yes,,,,,reduced,reduced,reduced,,no,potassium acetate,CAS:4251-29-0,,,,,gene deletion: full; gene complementation,,,RP,21237280,PubMed,10.1016/j.fgb.2011.01.002,,lee2443@snu.ac.kr,no comments,Hokyoung Son,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2886,PHI:2388,UniProt,Q4U4T0,GenBank,DQ011663.2,,,E6,Chi2,,,,,,,5530,Metarhizium anisopliae,,E6,,bugs,685034,Dysdercus peruvianus (no common name found),,,,,endochitinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,19649636,PubMed,10.1007/s00294-009-0267-5,,aschrank@cbiot.ufrgs.br,Agrobacterium tumefaciens,Juliano Tomazzoni Boldo,2009,,Boldo_CurG_2009_Metarhizium_endChitinaseChi2,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2887,PHI:2388,UniProt,Q4U4T0,GenBank,DQ011663.2,,,E6,Chi2,,,,,,,5530,Metarhizium anisopliae,,E6,,bugs,685034,Dysdercus peruvianus (no common name found),,,,,endochitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,19649636,PubMed,10.1007/s00294-009-0267-5,,aschrank@cbiot.ufrgs.br,no comments,Juliano Tomazzoni Boldo,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2888,PHI:2389,UniProt,Q9SZA7,,At4g33300,,,Col-0,ADR1-L1,,,,,,PHI:2390; PHI:2391,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,disease resistance protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21911370,PubMed,10.1073/pnas.1113726108,,dangl@email.unc.edu.,Plant defence genes found in the host; deletion of these makes the plants more susceptible to infections,Vera Bonardi,2011,,Bonardi-2011-Expanded functions f,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2889,PHI:2390,UniProt,Q9LZ25,,At5g04720,,,Col-0,ADR1-L2,,,,,,PHI:2389; PHI:2391,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,disease resistance protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21911370,PubMed,10.1073/pnas.1113726108,,dangl@email.unc.edu.,Plant defence genes found in the host; deletion of these makes the plants more susceptible to infections,Vera Bonardi,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2890,PHI:2391,UniProt,Q9LVT1,,At5g47280,,,Col-0,ADR1-L3,,,,,,PHI:2389; PHI:2390,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,disease resistance protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21911370,PubMed,10.1073/pnas.1113726108,,dangl@email.unc.edu.,Plant defence genes found in the host; deletion of these makes the plants more susceptible to infections,Vera Bonardi,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2891,PHI:2389,UniProt,Q9SZA7,,At4g33300,,,Col-0,ADR1-L1,,,,,,PHI:2390; PHI:2391,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,disease resistance protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21911370,PubMed,10.1073/pnas.1113726108,,dangl@email.unc.edu.,Plant defence genes found in the host; deletion of these makes the plants more susceptible to infections,Vera Bonardi,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2892,PHI:2390,UniProt,Q9LZ25,,At5g04720,,,Col-0,ADR1-L2,,,,,,PHI:2389; PHI:2391,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,disease resistance protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21911370,PubMed,10.1073/pnas.1113726108,,dangl@email.unc.edu.,Plant defence genes found in the host; deletion of these makes the plants more susceptible to infections,Vera Bonardi,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2893,PHI:2391,UniProt,Q9LVT1,,At5g47280,,,Col-0,ADR1-L3,,,,,,PHI:2389; PHI:2390,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,disease resistance protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,21911370,PubMed,10.1073/pnas.1113726108,,dangl@email.unc.edu.,Plant defence genes found in the host; deletion of these makes the plants more susceptible to infections,Vera Bonardi,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2894,PHI:2392,UniProt,Q5ALK1,,CaO19.9150,,,SC5314,Gat2,,,,,,,5476,Candida albicans,,SN152,,rodents,10090,Mus musculus (related: house mouse),,,,,GATA-type zinc finger transcription factor,,,,reduced virulence,,,,yes,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22276126,PubMed,10.1371/journal.pone.0029707,,huanggh@im.ac.cn,no comments,Han Du,2012,,Du-2012-Roles of Candida alb,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2895,PHI:2393,UniProt,A0A098D1J7,EMBL,FGRAMPH1_01T00053,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,(O-methylsterigmatocystin oxidoreductase),,,,,,,5518,Fusarium graminearum,,CS3005,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Kennedy,,,spike,,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,19888824,PubMed,10.1094/MPMI-22-12-1588,,donald.gardiner@csiro.au,no comments,Donald M. Gardiner,2009,,Gardiner novel genes pdf,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2896,PHI:2393,UniProt,A0A098D1J7,EMBL,FGRAMPH1_01T00053,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,(O-methylsterigmatocystin oxidoreductase),,,,,,,5518,Fusarium graminearum,,CS3005,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Sumai,,,spike,,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,19888824,PubMed,10.1094/MPMI-22-12-1588,,donald.gardiner@csiro.au,no comments,Donald M. Gardiner,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2897,PHI:2394,UniProt,I1S104,,FGSG_10397,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FGSG_10397,,,,,,,5518,Fusarium graminearum,,CS3005,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Kennedy,,,spike,,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,19888824,PubMed,10.1094/MPMI-22-12-1588,,donald.gardiner@csiro.au,no comments,Donald M. Gardiner,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2898,PHI:2395,UniProt,A0A0E0RP23,EMBL,FGRAMPH1_01T02393,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,GzSYN1,,,,,,,5518,Fusarium graminearum,,GZ03643,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Sangrok,,,spike,syntaxins,,,,reduced virulence,,,,,,wild type,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20102747,PubMed,10.1016/j.fgb.2010.01.005,,lee2443@snu.ac.kr,no comments,Sae-Yeon Hong,2010,,Hong-2010-Functional analyses,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2899,PHI:2396,UniProt,I1RZS5,,FGSG_09928.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,GzSYN2,,,,,,,5518,Fusarium graminearum,,GZ03643,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),subsp. vulgare cv. Sangrok,,,spike,syntaxins,,,,reduced virulence,,,,,,,reduced,wild type; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20102747,PubMed,10.1016/j.fgb.2010.01.005,,lee2443@snu.ac.kr,no comments,Sae-Yeon Hong,2010,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2900,PHI:2397,UniProt,C6L683,,AB488404,,,,ChSte11,,,,,,,5016,Bipolaris maydis,,HITO7711,,monocots,4577,Zea mays (related: maize),,,,leaf,,,,MAPK signaling pathway,loss of pathogenicity,,yes,,,,reduced,reduced,reduced; aberrant,,no,"hydrogen peroxide; copper, ion (cu2+)","hydrogen peroxide: CAS:7722-84-1; copper,  ion: CAS:15158-11-9",,,,,gene deletion: full; gene complementation,,,RP,19547975,PubMed,10.1007/s00294-009-0257-7,,chihiro@kais.kyoto-u.ac.jp,Mutants sensitive to heavy metal and oxidative stress. Cochliobolus heterostrophus is pathogen anamorph name,Kosuke Izumitsu,2009,,Izumitsu_CurG_2009_CochHet_ChSte11,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2901,PHI:2398,UniProt,Q9UVN7,,AAF05913,,,C4,Chk1,,,,,,,5016,Bipolaris maydis,,HITO7711,,monocots,4577,Zea mays (related: maize),,,,leaf,,,,MAPK signaling pathway,reduced virulence,,yes,,,,reduced,reduced,reduced; aberrant,,no,"hydrogen peroxide; copper, ion (cu2+)","hydrogen peroxide: CAS:7722-84-1; copper,  ion: CAS:15158-11-9",,,,,gene deletion: full; gene complementation,,,RP,19547975,PubMed,10.1007/s00294-009-0257-7,,chihiro@kais.kyoto-u.ac.jp,Mutants sensitive to heavy metal and oxidative stress. Cochliobolus heterostrophus is pathogen anamorph name,Kosuke Izumitsu,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2902,PHI:2399,UniProt,I1S5P3,,FGSG_12164,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,Fgp1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,toxin synthesis. pathogenicity and reproduction,,,,reduced virulence,,,,yes,,reduced,reduced,wild type,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,22693448,PubMed,10.1371/journal.ppat.1002724,,hckist@umn.edu,no comments,Wilfried Jonkers,2012,,Jonkers-2012-The Wor1-like Protei,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2903,PHI:2400,UniProt,I1S215,,FGSG_10796,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,Fgp2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,toxin synthesis. pathogenicity and reproduction,,,,unaffected pathogenicity,,,,no,,wild type,wild type,wild type,wild type,no,,,,,,,gene disruption; gene complementation,,,RP,22693448,PubMed,10.1371/journal.ppat.1002724,,hckist@umn.edu,no comments,Wilfried Jonkers,2012,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2904,PHI:2399,UniProt,I1S5P3,,FGSG_12164,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,Fgp1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Bobwhite,,,spike,toxin synthesis. pathogenicity and reproduction,,,,reduced virulence,,,,yes,,reduced,reduced,wild type,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,22693448,PubMed,10.1371/journal.ppat.1002724,,hckist@umn.edu,no comments,Wilfried Jonkers,2012,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2905,PHI:2400,UniProt,I1S215,,FGSG_10796,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,Fgp2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Bobwhite,,,spike,toxin synthesis. pathogenicity and reproduction,,,,unaffected pathogenicity,,,,no,,wild type,wild type,wild type,wild type,no,,,,,,,gene disruption; gene complementation,,,RP,22693448,PubMed,10.1371/journal.ppat.1002724,,hckist@umn.edu,no comments,Wilfried Jonkers,2012,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2906,PHI:2399,UniProt,I1S5P3,,FGSG_12164,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,Fgp1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,seedling,toxin synthesis. pathogenicity and reproduction,,,,reduced virulence,,,,yes,,reduced,reduced,wild type,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,22693448,PubMed,10.1371/journal.ppat.1002724,,hckist@umn.edu,no comments,Wilfried Jonkers,2012,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2907,PHI:2400,UniProt,I1S215,,FGSG_10796,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,Fgp2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,seedling,toxin synthesis. pathogenicity and reproduction,,,,unaffected pathogenicity,,,,no,,wild type,wild type,wild type,wild type,no,,,,,,,gene disruption; gene complementation,,,RP,22693448,PubMed,10.1371/journal.ppat.1002724,,hckist@umn.edu,no comments,Wilfried Jonkers,2012,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2908,PHI:2401,UniProt,G0T3B3,,GQ359822,,,Nockwang,CaRING1,,,,,,,339,Xanthomonas campestris,456327,pv. vesicatoria strain Ds1,,eudicots,4072,Capsicum annuum (no common name found),cv. Nockwang,,,leaf,E3 ubiquitin ligase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,compromised hypersensitive cell death and weakened defense response,altered gene expression / gene regulation: silencing,,,RP,21628629,PubMed,10.1104/pp.111.177568,,bkhwang@korea.ac.kr,Virus-induced gene silencing,Dong Hyuk Lee,2011,,Lee-2011-The Pepper E3 Ubiqui,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2909,PHI:2401,UniProt,G0T3B3,,GQ359822,,,Nockwang,CaRING1,,,,,,,339,Xanthomonas campestris,456327,pv. vesicatoria strain Bv5-4a,,eudicots,4072,Capsicum annuum (no common name found),cv. Nockwang,,,leaf,E3 ubiquitin ligase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,compromised hypersensitive cell death and weakened defense response,altered gene expression / gene regulation: silencing,,,RP,21628629,PubMed,10.1104/pp.111.177568,,bkhwang@korea.ac.kr,Virus-induced gene silencing,Dong Hyuk Lee,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2910,PHI:2401,UniProt,G0T3B3,,GQ359822,,,Nockwang,CaRING1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,E3 ubiquitin ligase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,enhanced defense response and cell death,altered gene expression / gene regulation: overexpression,,,RP,21628629,PubMed,10.1104/pp.111.177568,,bkhwang@korea.ac.kr,Agrobacterium tumefaciens strain GV3101,Dong Hyuk Lee,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2911,PHI:2401,UniProt,G0T3B3,,GQ359822,,,Nockwang,CaRING1,,,,,,,272952,Hyaloperonospora arabidopsidis,,Noco2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,E3 ubiquitin ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,enhanced defense response and cell death,altered gene expression / gene regulation: overexpression,,,RP,21628629,PubMed,10.1104/pp.111.177568,,bkhwang@korea.ac.kr,Agrobacterium tumefaciens strain GV3101,Dong Hyuk Lee,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2912,PHI:2402,UniProt,Q5G7K8,,,,,,ATR13,,,,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22194684,PubMed,10.1371/journal.ppat.1002428,,stask@berkeley.edu,no comments,Lauriebeth Leonelli,2011,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2913,PHI:2403,UniProt,A9QUB2,,EU263917,,,114,CSN1,,,,,,,169388,Fusarium solani,,114,,eudicots,3888,Pisum sativum (related: pea),,,,seedling; root; pod,chitosanase,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,20419375,PubMed,10.1007/s00294-010-0299-x,,lics1011@sina.com,A. tumefaciens LBA 4404,Huaiwei Liu,2010,,Liu_CurGen_2010_Fsolan_chitosanasei,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2914,PHI:2403,UniProt,A9QUB2,,EU263917,,,114,CSN1,,,,,,,169388,Fusarium solani,,114,,eudicots,3888,Pisum sativum (related: pea),,,,seedling; root; pod,chitosanase,,,,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,20419375,PubMed,10.1007/s00294-010-0299-x,,lics1011@sina.com,A. tumefaciens LBA 4404,Huaiwei Liu,2010,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2915,PHI:2404,UniProt,G4N906,,MGG10097,,,70-15 / ATCC MYA-4617 / FGSC 8958,SLP 1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector protein,,,,effector (plant avirulence determinant),,no,no,yes,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22267486,PubMed,10.1105/tpc.111.092957,,n.j.talbot@e xeter.ac.uk,Reduced virulence. Targeted Gene Silencing of CEBiP in Rice Restores the ability of Dslp1 mutants of M. oryzae to cause rice blast disease.,Thomas A. Mentlak,2012,,Mentlak-2012-Effector-mediated su,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2916,PHI:2405,UniProt,G5EH08,,MGG02897,,,70-15 / ATCC MYA-4617 / FGSC 8958,MoSSK1,,,,,,,318829,Magnaporthe oryzae,,Kita 1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,no,,,,wild type,,aberrant,,no,fludioxonil,CAS:131341-86-1,,,,,gene disruption,,,RP,18726099,PubMed,10.1007/s00294-008-0211-0,,tmotoyam@riken.jp,Disrupted Mossk1 strain had increased sensitivity to high osmolarity and decreased sensitivity to fludioxonil.,Takayuki Motoyama,2008,,Motoyama_CurGen2008_response regulatorMo,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2917,PHI:2406,UniProt,G4N7Y2,,MGG03516,,,70-15 / ATCC MYA-4617 / FGSC 8958,MoSKN7,,,,,,,318829,Magnaporthe oryzae,,Kita 1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,response regulator,,,,unaffected pathogenicity,,no,,,,wild type,,aberrant,,no,fludioxonil,CAS:131341-86-1,,,,,gene disruption,,,RP,18726099,PubMed,10.1007/s00294-008-0211-0,,tmotoyam@riken.jp,The delta Moskn7 strain hadslightly decreased sensitivity to fludioxonil,Takayuki Motoyama,2008,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2918,PHI:2407,UniProt,G4NCR0,,MGG00345,,,70-15 / ATCC MYA-4617 / FGSC 8958,MoRIM15,,,,,,,318829,Magnaporthe oryzae,,Kita 1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,response regulator homolog gene,,,,reduced virulence,,no,,,,wild type,,aberrant,,no,fludioxonil,CAS:131341-86-1,,,,,gene disruption,,,RP,18726099,PubMed,10.1007/s00294-008-0211-0,,tmotoyam@riken.jp,no comments,Takayuki Motoyama,2008,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2919,PHI:2408,UniProt,I1RJD6,GenBank,Fg03951.1,,,PH-1,FgMT1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,sphingolipid C-9 methyltransferases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,MsDef1 and RsAFP2,,,,,,gene deletion: full,,,RP,19028992,PubMed,10.1128/EC.00255-08,,dshah@danforthcenter.org,The C-9 methyl group is not a critical structural feature of the GlcCer receptor required for the antifungal action of plant defensins,Vellaisamy Ramamoorthy,2009,,Ramamoorthy-2009-Sphingolipid C-9 Met,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2920,PHI:2409,UniProt,I1RNL0,GenBank,Fg05593.1,,,PH-1,FgMT2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike,sphingolipid C-9 methyltransferases,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,MsDef1 and RsAFP2,,,,,,gene deletion: full; gene complementation,,,RP,19028992,PubMed,10.1128/EC.00255-08,,dshah@danforthcenter.org,The C-9 methyl group is not a critical structural feature of the GlcCer receptor required for the antifungal action of plant defensins,Vellaisamy Ramamoorthy,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2921,PHI:2408,UniProt,I1RJD6,GenBank,Fg03951.1,,,PH-1,FgMT1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,sphingolipid C-9 methyltransferases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,MsDef1 and RsAFP2,,,,,,gene deletion: full,,,RP,19028992,PubMed,10.1128/EC.00255-08,,dshah@danforthcenter.org,The C-9 methyl group is not a critical structural feature of the GlcCer receptor required for the antifungal action of plant defensins,Vellaisamy Ramamoorthy,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2922,PHI:2409,UniProt,I1RNL0,GenBank,Fg05593.1,,,PH-1,FgMT2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,sphingolipid C-9 methyltransferases,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,MsDef1 and RsAFP2,,,,,,gene deletion: full; gene complementation,,,RP,19028992,PubMed,10.1128/EC.00255-08,,dshah@danforthcenter.org,The C-9 methyl group is not a critical structural feature of the GlcCer receptor required for the antifungal action of plant defensins,Vellaisamy Ramamoorthy,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2923,PHI:2408,UniProt,I1RJD6,GenBank,Fg03951.1,,,PH-1,FgMT1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,sphingolipid C-9 methyltransferases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,MsDef1 and RsAFP2,,,,,,gene deletion: full,,,RP,19028992,PubMed,10.1128/EC.00255-08,,dshah@danforthcenter.org,The C-9 methyl group is not a critical structural feature of the GlcCer receptor required for the antifungal action of plant defensins,Vellaisamy Ramamoorthy,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2924,PHI:2409,UniProt,I1RNL0,GenBank,Fg05593.1,,,PH-1,FgMT2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,sphingolipid C-9 methyltransferases,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,MsDef1 and RsAFP2,,,,,,gene deletion: full; gene complementation,,,RP,19028992,PubMed,10.1128/EC.00255-08,,dshah@danforthcenter.org,The C-9 methyl group is not a critical structural feature of the GlcCer receptor required for the antifungal action of plant defensins,Vellaisamy Ramamoorthy,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2925,PHI:2408,UniProt,I1RJD6,GenBank,Fg03951.1,,,PH-1,FgMT1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,sphingolipid C-9 methyltransferases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,MsDef1 and RsAFP2,,,,,,gene deletion: full,,,RP,19028992,PubMed,10.1128/EC.00255-08,,dshah@danforthcenter.org,The C-9 methyl group is not a critical structural feature of the GlcCer receptor required for the antifungal action of plant defensins,Vellaisamy Ramamoorthy,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2926,PHI:2409,UniProt,I1RNL0,GenBank,Fg05593.1,,,PH-1,FgMT2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,sphingolipid C-9 methyltransferases,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,MsDef1 and RsAFP2,,,,,,gene deletion: full; gene complementation,,,RP,19028992,PubMed,10.1128/EC.00255-08,,dshah@danforthcenter.org,The C-9 methyl group is not a critical structural feature of the GlcCer receptor required for the antifungal action of plant defensins,Vellaisamy Ramamoorthy,2009,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2927,PHI:2410,UniProt,Q5G7K8,,,,,,ATR13,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,18198274,PubMed,10.1073/pnas.0711215105,,stask@berkeley.edu,A. tumefaciens strain GV2260 / ATR13 recognition by its cognate RPP13 allele c onfers resistance to pathogens from different kingdoms that employ various infection strategies,Maike C. Rentel,2008,,Rentel-2008-Recognition of the H,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2928,PHI:2410,UniProt,Q5G7K8,,,,,,ATR13,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,18198274,PubMed,10.1073/pnas.0711215105,,stask@berkeley.edu,A. tumefaciens strain GV2260,Maike C. Rentel,2008,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2929,PHI:2410,UniProt,Q5G7K8,,,,,,ATR13,,,,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,18198274,PubMed,10.1073/pnas.0711215105,,stask@berkeley.edu,A. tumefaciens strain GV2260 / ATR13 recognition by its cognate RPP13 allele c onfers resistance to pathogens from different kingdoms that employ various infection strategies,Maike C. Rentel,2008,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2930,PHI:2410,UniProt,Q5G7K8,,,,,,ATR13,,,,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,18198274,PubMed,10.1073/pnas.0711215105,,stask@berkeley.edu,A. tumefaciens strain GV2260,Maike C. Rentel,2008,,,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2931,PHI:2411,UniProt,A7F946,,SS1G_14127.3,,,1980,Ss-ggt1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold; stem rot,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaflet,gamma-glutamyl transpeptidase,,,,reduced virulence,,no,yes,no,,,,,,no,,,,,,,gene deletion: full,,,AR,22046959,PubMed,10.1094/MPMI-06-11-0159,,narollinsj@ufl.edu,no comments,Moyi Li,2012,,sclerotinia,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2932,PHI:2412,UniProt,B9VSG8,,FJ599764,,,97-2,lipA,,,,,,,339,Xanthomonas campestris,,97-2,bacterial spot,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7998,,,leaf,lipase,,,,reduced virulence,,,,,,,,wild type,,no,olive oil,CAS:8001-25-0,,,,,gene disruption; gene complementation,,,AR,22176521,PubMed,10.1111/J.1364-3703.2011.00771.X,,saulb@agri.huji.ac.il,The lipA mutant was compromised in its ability to grow on olive oil as sole carbon source when compared with the wild-type. Transformation of the lipA mutant with plasmid pBBR1-lipA (complemented strain lipA - /comp) restored both the growth and lipolytic activity of the mutant under these conditions.,Dafna Tamir-Ariel,2012,,Tamir-Ariel-2012-A secreted lipolytic,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2933,PHI:2413,UniProt,B2Z3E2,,EU589331,,,M1.001,Cgg1,,,,,,,31870,Colletotrichum graminicola,645133,M1.001,anthracnose; stalk rot; leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Jubilee,,,leaf; stem,encodes a Ga sub-unit that regulates sexual and asexual development and secondary metabolism,,,,reduced virulence,,yes,,yes,,reduced; aberrant,,reduced,wild type,no,,,,,,,gene disruption; gene complementation,,,RP,18448365,PubMed,10.1016/j.fgb.2008.03.008,,vaillan@uky.edu,no comments,C. Venard,2008,,Venard-2008-The role of a fadA o,Batch010a,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2934,PHI:2414,UniProt,D2X3B5,,GQ499184,,,,AaGa1,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot (Citrus),eudicots,229630,Citrus x tangelo (related: tangelo),,,,leaf,class I Ga subunit of the GTP-binding protein,,,G protein signaling transduction pathway,unaffected pathogenicity,,,,,,reduced,,wild type,,no,cyclic AMP; 1-methyl-3-isobutylxanthine; theophylline; atropine; potassium chloride,cyclic AMP: CAS:60-92-4; 1-methyl-3-isobutylxanthine: CAS:28822-58-4; theophylline: CAS:58-55-9; atropine: CAS:51-55-8; potassium chloride: CAS:7447-40-7,,,,,gene disruption; gene complementation,,,RP,19949798,PubMed,10.1007/s00294-009-0278-2,,krchung@ufl.edu,"Application of a cAMP inhibitor atropine or theophylline, or IBMX (3-isobutyl-1-methylxanthine) suppressed conidiation in the wild type or in the strains harboring a functional copy of AGA1. In contrast, cAMP or theophylline at 1 but not 10 mM partially restored conidiation in the T1 and T2 null mutants. / Null mutants more sensitive to KCl.",Nan-Yi Wang,2010,,Wang_CurG_Aalternata_citrus_Galph-3081920046,Batch010b,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2935,PHI:2415,UniProt,P57051,,VC_0086,,,ATCC 39315 / El Tor Inaba N16961,tatA,chromosome 1,,,,,PHI:2416; PHI:2417,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,intestine,translocate folded proteins; virulence,,,Tat pathway,reduced virulence,,yes,,yes,,,,wild type; aberrant,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,19480715,PubMed,10.1186/1471-2180-9-114,,kanbiao@icdc.cn,Mutants show reduced biofilm formation capability,Lijuan Zhang,2009,,Zhang_Vibrio_cholarae,Batch010b,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2936,PHI:2416,UniProt,P57063,,VC_0087,,,ATCC 39315 / El Tor Inaba N16961,tatB,chromosome 1,,,,,PHI:2415; PHI:2417,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,intestine,translocate folded proteins; virulence,,,Tat pathway,reduced virulence,,yes,,yes,,,,wild type; aberrant,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,19480715,PubMed,10.1186/1471-2180-9-114,,kanbiao@icdc.cn,Mutants show reduced biofilm formation capability,Lijuan Zhang,2009,,,Batch010b,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2937,PHI:2417,UniProt,Q9KVQ3,,VC_0088,,,ATCC 39315 / El Tor Inaba N16961,tatC,chromosome 1,,,,,PHI:2415; PHI:2416,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,intestine,translocate folded proteins; virulence,,,Tat pathway,reduced virulence,,yes,,yes,,,,wild type; aberrant,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,19480715,PubMed,10.1186/1471-2180-9-114,,kanbiao@icdc.cn,Mutants show reduced biofilm formation capability,Lijuan Zhang,2009,,,Batch010b,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2938,PHI:2418,UniProt,I1RKF3,,FGSG_04355.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,CID1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,corn ear; stem,C-type cyclins,,,,reduced virulence,yes,,,,,reduced; aberrant,defective,reduced; aberrant,wild type,no,"nickel, ion (ni2+); cadmium chloride, monohydrate; hydrogen peroxide; cadmium, ion (cd2+)","nickel,  ion (ni2+): CAS:14701-22-5; cadmium   chloride,  monohydrate: CAS:35658-65-2; hydrogen peroxide: CAS:7722-84-1; cadmium,  ion (cd2+): CAS:22537-48-0",,,,,gene deletion: full; gene complementation,,,RP,19909822,PubMed,10.1016/j.fgb.2009.11.001,,jinrong@purdue.edu,The D cid1 mutant is defective in stress responses,Xiaoying Zhou,2010,,Zhou-2010-The CID1 cyclin C-li-0733109806,Batch010b,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2939,PHI:2419,UniProt,I1RKF3,,FGSG_04355.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,CID1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Norm,,,spike; stem,C-type cyclins,,,,reduced virulence,yes,,,,,reduced; aberrant,defective,reduced; aberrant,wild type,no,"nickel, ion (ni2+); cadmium chloride, monohydrate; hydrogen peroxide; cadmium, ion (cd2+)","nickel,  ion (ni2+): CAS:14701-22-5; cadmium   chloride,  monohydrate: CAS:35658-65-2; hydrogen peroxide: CAS:7722-84-1; cadmium,  ion (cd2+): CAS:22537-48-0",,,,,gene deletion: full; gene complementation,,,RP,19909822,PubMed,10.1016/j.fgb.2009.11.001,,jinrong@purdue.edu,The D cid1 mutant is defective in stress responses,Xiaoying Zhou,2010,,,Batch010b,2012-07-27,MC,,,,,,,,,,,,,
,,Record 2940,PHI:2420,UniProt,Q4VKJ6,,AY842877,,,Emoy2,ATR1,,PstDC3000 expressing AvrRPS4N-ATR1105-368Emoy2-HA,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,does not contain RPP1-Nd-0 or RPP1-WsB,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,no hypersensitive response,functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,Sohn-2007-The downy mildew eff,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2941,PHI:2420,UniProt,Q4VKJ6,,AY842877,,,Emoy2,ATR1,,PstDC3000 expressing AvrRPS4N-ATR1105-368Emoy2-HA,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Niederzenz-0,RPP1-Nd-0,UniProt: D9IW02,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,resistance hypersensitive response,functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2942,PHI:2420,UniProt,Q4VKJ6,,AY842877,,,Emoy2,ATR1,,PstDC3000 expressing AvrRPS4N-ATR1105-368Emoy2-HA,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Wassilewskija-0,RPP1-WsB,UniProt: Q9LSV1,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,resistance hypersensitive response,functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2943,PHI:2421,UniProt,Q4VKJ1,,AY842883,,,Cala2,ATR1,,PstDC3000 expressing AvrRPS4N-ATR1105-380Cala2-HA,,,,,272952,Hyaloperonospora arabidopsidis,,Cala2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,does not contain RPP1-Nd-0 or RPP1-WsB,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,no hypersensitive response,functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2944,PHI:2421,UniProt,Q4VKJ1,,AY842883,,,Cala2,ATR1,,PstDC3000 expressing AvrRPS4N-ATR1105-380Cala2-HA,,,,,272952,Hyaloperonospora arabidopsidis,,Cala2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Niederzenz-0,RPP1-Nd-0,UniProt: D9IW02,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,no hypersensitive response,functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2945,PHI:2421,UniProt,Q4VKJ1,,AY842883,,,Cala2,ATR1,,PstDC3000 expressing AvrRPS4N-ATR1105-380Cala2-HA,,,,,272952,Hyaloperonospora arabidopsidis,,Cala2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Wassilewskija-0,RPP1-WsB,UniProt: Q9LSV1,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,no hypersensitive response,functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2946,PHI:2422,UniProt,Q5G7L2,,AY785302,,,Emoy2,ATR13,,PstDC3000 expressing AvrRPS4N-ATR1342-154Emoy2-HA,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,RPP13-Col (does not recognise Emoy2 ATR1 or Emco5 ATR1),UniProt: Q9M667,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,no hypersensitive response,functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2947,PHI:2422,UniProt,Q5G7L2,,AY785302,,,Emoy2,ATR13,,PstDC3000 expressing AvrRPS4N-ATR1342-154Emoy2-HA,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Niederzenz-0,RPP13-Nd,UniProt: Q9M667,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,no hypersensitive response (24h after infection),functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2948,PHI:2422,UniProt,Q5G7L2,,AY785302,,,Emoy2,ATR13,,PstDC3000 expressing AvrRPS4N-ATR1342-154Emoy2-HA,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-5,transgenic Col-5 (RPP13-Nd),UniProt: Q9M667,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,no hypersensitive response (24h after infection),functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2949,PHI:2423,UniProt,Q5G7K8,,AY785305,,,Emco5,ATR13,,PstDC3000 expressing AvrRPS4N-ATR1342-154Emco5-HA,,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,RPP13-Col (does not recognise Emoy2 ATR1 or Emco5 ATR1),UniProt: Q9M667,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,no hypersensitive response,functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2950,PHI:2423,UniProt,Q5G7K8,,AY785305,,,Emco5,ATR13,,PstDC3000 expressing AvrRPS4N-ATR1342-154Emco5-HA,,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Niederzenz-0,RPP13-Nd,UniProt: Q9M667,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,strong hypersensitive response,functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2951,PHI:2423,UniProt,Q5G7K8,,AY785305,,,Emco5,ATR13,,PstDC3000 expressing AvrRPS4N-ATR1342-154Emco5-HA,,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-5,transgenic Col-5 (RPP13-Nd),UniProt: Q9M667,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,strong hypersensitive response,functional test in host: transient expression,,,RP,18165328,PubMed,10.1105/tpc.107.054262,Plant Cell.2007 Dec;19(12):4077-90,jonathan.jones@tsl.ac.uk,Pseudomonas syringae pv tomato DC3000 used to express the genes using effector detector vector with fusion of bacterial effector AvrRPS4 promoter and N-terminal 136 amino acids fused to Hpa effector.,Kee Hoon Sohn,2007,,,Batch010b/AC First Host Target Curation update,2016-01-15,MC; RRes,,,,,,,,,,,,,
,,Record 2952,PHI:2424,UniProt,J9VE33,GenBank,XP_566613.1,,,JEC21,Cn Sp1,,,,,,,5207,Cryptococcus neoformans,235443,H99,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),,,,,cell wall integrity and virulence factors,,,PKC1 pathway,reduced virulence,,,,,,,,aberrant,,no,caspofungin; sorbitol,caspofungin: CAS:162808-62-0; sorbitol: CAS:50-70-4,,,,,gene deletion: full; gene complementation,,,RP,21487010,PubMed,10.1074/jbc.M111.230268,,williamsonpr@mail.nih.gov,Sensitivity to Caspofungin suggesting a role for Cn SP1 in resistance to this cell wall-active antifungal agent. / Cn sp1 did not have a growth restriction at 37 °C with sorbitol.,Amos Adler,2011,,Adler-2011-A Novel Specificity,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2953,PHI:2425,UniProt,Q6RKG2,,AY495643,,,C4; ATCC 48331,PKS2,,,,,,,5016,Bipolaris maydis,665024,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A,,,leaf,T-toxin production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,16529376,PubMed,10.1094/MPMI-19-0139,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,Scott E. Baker,2006,,Baker_MPMI_2006,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2954,PHI:2425,UniProt,Q6RKG2,,AY495643,,,C4; ATCC 48331,PKS2,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A,,,leaf,T-toxin production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,16529376,PubMed,10.1094/MPMI-19-0139,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,Scott E. Baker,2006,,,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2955,PHI:2426,UniProt,D0U2D1,,ACY39289.1,,,IPO3,Avr2,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain Fol007,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. C32,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19228334,PubMed,10.1111/j.1365-313X.2009.03838.x,,m.rep@uva.nl,no comments,Petra M. Houterman,2009,,Houterman-2009-The effector protein,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2956,PHI:2426,UniProt,D0U2D1,,ACY39289.1,,,IPO3,Avr2,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain Fol007,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),90E341F line,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19228334,PubMed,10.1111/j.1365-313X.2009.03838.x,,m.rep@uva.nl,no comments,Petra M. Houterman,2009,,,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2957,PHI:2426,UniProt,D0U2D1,,ACY39289.1,,,IPO3,Avr2,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain Fol007,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,19228334,PubMed,10.1111/j.1365-313X.2009.03838.x,,m.rep@uva.nl,Agrobacterium tumefaciens strain GV3101(pMP90) mediated transient expression of Avr2 in plant,Petra M. Houterman,2009,,,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2958,PHI:2427,UniProt,I1RCN9,,FGSG_01362.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FgVELB,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Jimai 22,,,spike,"vegetative differentiation, secondary metabolism and virulence",,,,reduced virulence,,,,,,increased,,reduced; aberrant,,no,potassium chloride; sodium chloride; fludioxonil; iprodione; Congo red; caffeine,"potassium chloride: CAS:7447-40-7; sodium chloride: CAS:7647-14-5; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; Congo red: CAS:573-58-0; caffeine: CAS:58-08-2",,,,,gene disruption; gene complementation,,,RP,22713714,PubMed,10.1016/j.fgb.2012.06.005,,zhma@zju.edu.cn,"The mutant showed increased sensitivity to the phenylpyrrole fungicide fludioxonil, but not significantly to the dicarboximide fungicide iprodione. / D FgVelB-2 displayed increased resistance significantly to congo red, to lesser extent, to caffeine. / D FgVelB-2 exhibited increased resistance to 1.2 M KCl, to a lesser extent,to 1.2 M NaCl",Jinhua Jiang,2012,,Jiang-2012-FgVELB is associated,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2959,PHI:2428,UniProt,F8UWJ7,,JF937063,,,var. grubii,ypd1,,,,,,,5207,Cryptococcus neoformans,235443,H99,meningoencephalitis,,,,Lethal pathogen phenotype,,,,phosphotransfer protein,,,Hog1-dependent signaling pathway,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,21642509,PubMed,10.1128/EC.05124-11,,ysbahn@yonsei.ac.kr,"A prior attempt to generate a ypd1 mutant in C. neofor-mans for functional analysis of Ypd1 was not successful, im-plying that Ypd1 may be essential for the viability of C. neo-formans",Jang-Won Lee,2011,,Lee-2011-Multiple Roles of Yp,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2960,PHI:2428,UniProt,F8UWJ7,,JF937063,,,var. grubii,ypd1,,,,,,,5207,Cryptococcus neoformans,235443,H99,meningoencephalitis,,,,Lethal pathogen phenotype,,,,phosphotransfer protein,,,Hog1-dependent signaling pathway,lethal,,,,,,,,,,yes,,,,,,,promoter mutation,,,RP,21642509,PubMed,10.1128/EC.05124-11,,ysbahn@yonsei.ac.kr,"The PCTR4 ::YPD1 strain clearly exhibited growth defects in YNB medium containing CuSO4, which represses the CTR4 promoter, compared to the growth of the WT strain (Fig. 1C). These data suggest that Ypd1 is essential for the viability of C. neoformans.",Jang-Won Lee,2011,,,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2961,PHI:2429,UniProt,G9DDS6,,JF932502,,,Bb0062,Bbslt2,,,,,,,176275,Beauveria bassiana,,Bb0062,white muscardine,butterflies,7116,Pieris brassicae (related: large cabbage white),,,,larva,MAP kinase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,Congo red; driselase,Congo red: CAS:573-58-0; driselase: CAS:85186-71-6,,,,,gene deletion: partial; gene complementation,,,RP,22587950,PubMed,10.1016/j.fgb.2012.05.002,,yjzhang@swu.edu.cn,The D Bbslt2 strain was more susceptible to cell wall lytic enzymes (Driselase) with a greater abundance of protoplasts seen released from mycelia compared to the wild-type parent,Xingdan Luo,2012,,Luo-2012-The MAP kinase Bbslt,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2962,PHI:2430,UniProt,I1RWG5,,FGSG_08634.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,areA,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,global nitrogen regulator,,,,reduced virulence,yes,,,,localized necrosis,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22702217,PubMed,10.1111/j.1574-6968.2012.02620.x,,lee2443@snu.ac.kr,no comments,Kyunghun Min,2012,,Min-2012-Functional analyses,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2963,PHI:2430,UniProt,I1RWG5,,FGSG_08634.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,areA,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,global nitrogen regulator,,,,reduced virulence,yes,,,,localized necrosis,,reduced,reduced,,no,urea,CAS:57-13-6,,,,,chemical complementation,,,RP,22702217,PubMed,10.1111/j.1574-6968.2012.02620.x,,lee2443@snu.ac.kr,"Chemical complementation by urea restored normal sexual development, whereas the virulence and tricho-thecene production were not affected by urea addition.",Kyunghun Min,2012,,,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2964,PHI:2431,UniProt,C9K1M7,,AB432914,,,SH20,ACTT2,,,,,,,5599,Alternaria alternata,,SH20,Alternaria brown spot,eudicots,229630,Citrus x tangelo (related: tangelo),,,,leaf,ACT-toxin biosynthesis,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,18986255,PubMed,10.1094/MPMI-21-12-1591,,kazuya@ag.kagawa-u.ac.jp,no comments,Y. Miyamoto,2008,,Miyamoto_2008_ACT,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2965,PHI:2432,UniProt,A0A098DMW0,EMBL,FGRAMPH1_01T14959,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FgRgsA,,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,regulators of G protein,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,22634273,PubMed,10.1016/j.fgb.2012.05.006,,lee2443@snu.ac.kr,no comments,Ae Ran Park,2012,,Park-2012-Functional analyses,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2966,PHI:2433,UniProt,I1RD16,,FGSG_01503,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FgRgsB,,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,regulators of G protein,,,,reduced virulence,,,,,,aberrant,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22634273,PubMed,10.1016/j.fgb.2012.05.006,,lee2443@snu.ac.kr,no comments,Ae Ran Park,2012,,,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2967,PHI:2434,UniProt,A0A0E0SIF3,EMBL,FGRAMPH1_01T19813,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FgFlbA,,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Eunpamil,,,spike,regulators of G protein,,,,reduced virulence,,,,,,reduced,reduced,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,22634273,PubMed,10.1016/j.fgb.2012.05.006,,lee2443@snu.ac.kr,no comments,Ae Ran Park,2012,,,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2968,PHI:2437,UniProt,Q5KL01,,CNC01260,,,JEC21,SNF1,,,,,,,5207,Cryptococcus neoformans,214684,JEC21,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"key regulator for the biosynthesis of the major virulence factors, stress resistance and alternative carbon source utilization",,,,reduced virulence,,,,,,,,reduced; aberrant,,no,sodium chloride; hygromycin B,sodium chloride: CAS:7647-14-5; hygromycin B: CAS:31282-04-9,,,,,gene deletion: full; gene complementation,,,RP,20719250,PubMed,10.1016/j.fgb.2010.08.002,,xudong82@nankai.edu.cn,"JEC21 snf1D was highly sensitive to 1.5 M NaCl, and to another toxic cation hygromycin B/ Sensitive to higher temperature",Jiao Yang,2010,,Yang-2010-Regulation of virule,Batch011,2012-09-18,MC,,,,,,,,,,,,,
,,Record 2969,PHI:2438,UniProt,Q29YB0,EMBL,AY877346,,,,MgFus3,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,leaf blotch,monocots,4564,Triticum (related: wheat),cv. Scipion,,,seedling; leaf,putative MAP kinase,,,MAPK pathway,loss of pathogenicity,,no,yes,,chlorosis,reduced,,aberrant,wild type,no,,,,,,,gene disruption,,,RP,20507446,PubMed,10.1111/J.1364-3703.2006.00337.X,,gert.kema@wur.nl,no comments,Arnaud Cousin,2006,,Cousin-2006-The MAP kinase-encod,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2970,PHI:2438,UniProt,Q29YB0,EMBL,AY877346,,,,MgFus3,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,leaf blotch,monocots,4564,Triticum (related: wheat),cv. Obelisk,,,seedling; leaf,putative MAP kinase,,,MAPK pathway,loss of pathogenicity,,no,yes,,chlorosis,reduced,,aberrant,wild type,no,,,,,,,gene disruption,,,RP,20507446,PubMed,10.1111/J.1364-3703.2006.00337.X,,gert.kema@wur.nl,no comments,Arnaud Cousin,2006,,,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2971,PHI:2439,UniProt,C5A845,,bglu_1g00490,,,BGR1,PidS,,,,,,,337,Burkholderia glumae,,411gr-6,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Trenasse,,,panicle,sensor histidine kinase / two-component regulatory system (TCRS),,,shikimic acid pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,hypersensitive response,gene deletion: full; gene complementation,,,RP,22364153,PubMed,10.1111/J.1364-3703.2012.00787.X,,jham@agcenter.lsu.edu,no comments,Hari Sharan Kark,2012,,Karki-2012-A conserved two-comp,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2972,PHI:2440,UniProt,C5A846,,bglu_1g00500,,,BGR1,PidR,,,,,,,337,Burkholderia glumae,,411gr-6,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Trenasse,,,panicle,response regulator/ two-component regulatory,,,shikimic acid pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,hypersensitive response,gene deletion: full; gene complementation,,,RP,22364153,PubMed,10.1111/J.1364-3703.2012.00787.X,,jham@agcenter.lsu.edu,no comments,Hari Sharan Kark,2012,,Karki-2012-A conserved two-comp,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2973,PHI:2439,UniProt,C5A845,,bglu_1g00490,,,BGR1,PidS,,,,,,,337,Burkholderia glumae,,411gr-6,panicle blight,monocots,4679,Allium cepa (related: onion),,,,panicle,sensor histidine kinase / two-component regulatory system (TCRS),,,shikimic acid pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,hypersensitive response,gene deletion: full; gene complementation,,,RP,22364153,PubMed,10.1111/J.1364-3703.2012.00787.X,,jham@agcenter.lsu.edu,no comments,Hari Sharan Kark,2012,,Karki-2012-A conserved two-comp,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2974,PHI:2440,UniProt,C5A846,,bglu_1g00500,,,BGR1,PidR,,,,,,,337,Burkholderia glumae,,411gr-6,panicle blight,monocots,4679,Allium cepa (related: onion),,,,panicle,response regulator/ two-component regulatory,,,shikimic acid pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,hypersensitive response,gene deletion: full; gene complementation,,,RP,22364153,PubMed,10.1111/J.1364-3703.2012.00787.X,,jham@agcenter.lsu.edu,no comments,Hari Sharan Kark,2012,,Karki-2012-A conserved two-comp,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2975,PHI:2441,UniProt,F9XJV5,Ensembl Genomes,Mycgr3G75289,,,IPO323,MgAlg2,chromosome 9,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,leaf blotch,monocots,4564,Triticum (related: wheat),cv. Riband,,,leaf,"alpha-1,2-mannosyltransferase",,,,loss of pathogenicity,,yes,,,,,,aberrant,reduced,no,7-diethylamino-4-methylcoumarin,CAS:91-44-1,,,,,gene deletion: full; gene complementation,,,RP,21623954,PubMed,10.1111/j.1365-2958.2011.07701.x,,jason.rudd@bbsrc.ac.uk,Spores of DMgAlg2 mutants were hypersensitive to the cell wall disrupting agent calcofluor white,Juliet Motteram,2011,,Motteram-2011-Aberrant protein N-g,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2976,PHI:2443,UniProt,F7IY49,,AB571112.2,,,6605,PilA,,,,,,,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,wildfire disease,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,"bacterial biofilm formation, surface motility and virulence",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,22353307,PubMed,10.1111/J.1364-3703.2012.00789.X,,yuki@cc.okayama-u.ac.jp,no comments,Linh Chi Nguyen,2012,,Nguyen-2012-Type IV pilin is gly,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2977,PHI:2444,UniProt,G5EJ36,,AB571112.2,,,6605,tfpO,,,,,,,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,wildfire disease,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,"bacterial biofilm formation, surface motility and virulence",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,22353307,PubMed,10.1111/J.1364-3703.2012.00789.X,,yuki@cc.okayama-u.ac.jp,no comments,Linh Chi Nguyen,2012,,Nguyen-2012-Type IV pilin is gly,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2978,PHI:2445,UniProt,Q5H3K9,,XOO1208,,,KACC10331,ColR,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,22257308,PubMed,10.1111/J.1364-3703.2011.00777.X,,sonti@ccmb.res.in,no comments,Sujatha Subramoni,2012,,Subramoni-2012-The ColRS system of,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2979,PHI:2446,UniProt,Q5H3L0,,XOO1207,,,KACC10331,ColS,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,induced a rice basal defence response,gene disruption; gene complementation,,,RP,22257308,PubMed,10.1111/J.1364-3703.2011.00777.X,,sonti@ccmb.res.in,no comments,Sujatha Subramoni,2012,,Subramoni-2012-The ColRS system of,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2980,PHI:2447,,no data found,Broad,B0510_6765,,,,BcAtf1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,bZip transcription factor,,,,increased virulence (hypervirulence),,,,,,reduced,reduced,increased,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,22293085,PubMed,10.1111/J.1364-3703.2011.00778.X,,tudzyns@uni-muenster.de,no comments,Nora Temme,2012,,"Temme-2012-BcAtf1, a global reg",Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2981,PHI:2447,,no data found,Broad,B0510_6765,,,,BcAtf1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,fruit,bZip transcription factor,,,,increased virulence (hypervirulence),,,,,,reduced,reduced,increased,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,22293085,PubMed,10.1111/J.1364-3703.2011.00778.X,,tudzyns@uni-muenster.de,no comments,Nora Temme,2012,,"Temme-2012-BcAtf1, a global reg",Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2982,PHI:2448,UniProt,H9AWW9,,JN900389,,,,AaNoxA,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot (Citrus),eudicots,229630,Citrus x tangelo (related: tangelo),cv. Blanco,,,leaf,production of ROS,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,wild type,no,hydrogen peroxide; tert-butyl hydroperoxide (t-BHP); cumene hydroperoxide; menadione (MND); potassium superoxide (KO2); diamide; hematoporphyrin; rose bengal; triisobutylaluminum (TIBA); CHP; sodium lauryl sulfate (SDS); diphenyleneiodonium (DPI); APC 366; tin phosphide (SnP); arginine; nitroarginine,"hydrogen peroxide: CAS:7722-84-1; tert-butyl hydroperoxide: CAS:75-91-2; cumene hydroperoxide: CAS:80-15-9; menadione: CAS:58-27-5; potassium superoxide: CAS:12030-88-5; diamide: CAS:10465-78-8; hematoporphyrin: CAS:14459-29-1; rose bengal: CAS:11121-48-5; triisobutylaluminum: CAS:130565-62-7; CHP: CAS:177325-13-2; sodium lauryl sulfate: CAS:151-21-3; diphenyleneiodonium: CAS:244-54-2, 366; APC: CAS:178925-65-0; tin phosphide (SnP): CAS:25324-56-5; arginine: CAS:74-79-3; nitroarginine: CAS:2149-70-4",,,,,gene disruption; gene complementation,,,RP,22435666,PubMed,10.1111/J.1364-3703.2012.00799.X,,krchung@ufl.edu,Increased sensitivity to ROS-generating compounds,Siwy Ling Yang,2012,,Yang-2012-The NADPH oxidase-me,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2983,PHI:2448,UniProt,H9AWW9,,JN900389,,,,AaNoxA,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot (Citrus),eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,production of ROS,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,wild type,no,hydrogen peroxide; tert-butyl hydroperoxide (t-BHP); cumene hydroperoxide; menadione (MND); potassium superoxide (KO2); diamide; hematoporphyrin; rose bengal; triisobutylaluminum (TIBA); CHP; sodium lauryl sulfate (SDS); diphenyleneiodonium (DPI); APC 366; tin phosphide (SnP); arginine; nitroarginine,"hydrogen peroxide: CAS:7722-84-1; tert-butyl hydroperoxide: CAS:75-91-2; cumene hydroperoxide: CAS:80-15-9; menadione: CAS:58-27-5; potassium superoxide: CAS:12030-88-5; diamide: CAS:10465-78-8; hematoporphyrin: CAS:14459-29-1; rose bengal: CAS:11121-48-5; triisobutylaluminum: CAS:130565-62-7; CHP: CAS:177325-13-2; sodium lauryl sulfate: CAS:151-21-3; diphenyleneiodonium: CAS:244-54-2, 366; APC: CAS:178925-65-0; tin phosphide (SnP): CAS:25324-56-5; arginine: CAS:74-79-3; nitroarginine: CAS:2149-70-4",,,,,gene disruption; gene complementation,,,RP,22435666,PubMed,10.1111/J.1364-3703.2012.00799.X,,krchung@ufl.edu,Increased sensitivity to ROS-generating compounds,Siwy Ling Yang,2012,,Yang-2012-The NADPH oxidase-me,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2984,PHI:3491,UniProt,Q0GPY7,,DQ778942,,,F2/5,lhnR,,,,,,,373,Agrobacterium vitis,,F2/5,,eudicots,29760,Vitis vinifera (related: wine grape),,,,leaf,"tobacco hypersensitive responses, grape necrosis",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,22212449,PubMed,10.1111/J.1364-3703.2011.00774.X,,tjb1@cornell.edu,no comments,Desen Zheng,2012,,Zheng-2012-LhnR and upstream op,Batch012,2012-10-03,MC,,,,,,,,,,,,,
,,Record 2985,PHI:2450,UniProt,Q8J0U6,,AY083456,,,Race 4,ToxB,,,,,,,45151,Pyrenophora tritici-repentis,881954,race 5,tan spot,monocots,4564,Triticum (related: wheat),cv. 6B662,,,leaf,production of host-selective toxins,,,,reduced virulence,,yes,,,,,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21980935,PubMed,10.1111/J.1364-3703.2011.00748.X,,stephen.strelkov@ualberta.ca,no comments,Reem Aboukhaddour,2012,,Aboukhaddour-2012-RNA-mediated gene si,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2986,PHI:2451,UniProt,I1S3N8,,FGSG_11428,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FAEB1,,,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Roblin,,,spike,feruloyl esterase gene family,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,22483046,PubMed,10.1016/j.funbio.2012.01.007,,therese.ou ellet@agr.gc.ca,no comments,Margaret Balcerzak,2012,,Balcerzak-2012-The feruloyl esteras,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2987,PHI:2452,UniProt,I1S2N6,,FGSG_11036,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FAED1,,,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Roblin,,,spike,feruloyl esterase gene family,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,22483046,PubMed,10.1016/j.funbio.2012.01.007,,therese.ou ellet@agr.gc.ca,no comments,Margaret Balcerzak,2012,,Balcerzak-2012-The feruloyl esteras,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2988,PHI:2451,UniProt,I1S3N8,,FGSG_11428,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FAEB1,,,,,,PHI:2452,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Roblin,,,spike,feruloyl esterase gene family,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,22483046,PubMed,10.1016/j.funbio.2012.01.007,,therese.ou ellet@agr.gc.ca,no comments,Margaret Balcerzak,2012,,Balcerzak-2012-The feruloyl esteras,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2989,PHI:2452,UniProt,I1S2N6,,FGSG_11036,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FAED1,,,,,,PHI:2451,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Roblin,,,spike,feruloyl esterase gene family,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,22483046,PubMed,10.1016/j.funbio.2012.01.007,,therese.ou ellet@agr.gc.ca,no comments,Margaret Balcerzak,2012,,Balcerzak-2012-The feruloyl esteras,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2990,PHI:2453,UniProt,D9J222,,HM246662,,,,Snt2,,,,,,,5507,Fusarium oxysporum,61369,f. sp. melonis race 1; f. sp. melonis race 2,wilt (muskmelon),eudicots,3656,Cucumis melo (related: muskmelon),cv. Ein Dor,,,seedling,BAH/PHD-containing transcription factor,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene disruption,,,RP,21535351,PubMed,10.1111/J.1364-3703.2010.00683.X,,oded.yarden@huji.ac.il,no comments,Youlia Denisov,2011,,Denisov-2011-Inactivation of Snt2,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2991,PHI:2453,UniProt,D9J222,,HM246662,,,,Snt2,,,,,,,5507,Fusarium oxysporum,61369,f. sp. melonis race 1; f. sp. melonis race 2,wilt (muskmelon),eudicots,3656,Cucumis melo (related: muskmelon),cv. Ein Dor,,,seedling,BAH/PHD-containing transcription factor,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene mutation,,,RP,21535351,PubMed,10.1111/J.1364-3703.2010.00683.X,,oded.yarden@huji.ac.il,GV3101 and EHA105 strains of A. tumefaciens,Youlia Denisov,2011,,Denisov-2011-Inactivation of Snt3,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2992,PHI:2454,,no data found,MUMDB,Um10417,,,521,Nit2,,,,,,,5270,Ustilago maydis,,SG200,smut (maize),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf,positive regulator of nitrogen utilization / GATA transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22247264,PubMed,10.1128/EC.05191-11,,lvoll@biologie.uni-erlangen.de.,no comments,Robin J. Horst,2012,,Horst-2012-The Ustilago maydis,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2993,PHI:2455,UniProt,J9MZK9,,FOXG_08353,,,4287,CRE1,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain Fol007,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker C32,,,seedling,transcriptional repressor in filamentous fungi known to repress several CWDE genes and other genes required for assimilation of non-sugar carbon sources,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression,,,RP,19912543,PubMed,10.1111/j.1365-2958.2009.06922.x,,m.rep@uva.nl,"The Dfrp1 mutant the replacement of CRE1 with GST::CRE1 restored pathogenicity, growth on ethanol and expression of ICL1 and CWDE genes",Wilfried Jonkers,2009,,Jonkers-2009-Mutation of CRE1 in,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2994,PHI:2456,UniProt,D4IAW2,,EAM_2894,,,ATCC 49946 / CCPPB 0273 / Ea273 / 27-3,HrpL,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,alternative sigma factor HrpL positively regulates the transcrip-tion of structural and translocated components of the T3SS via hrp promoter elements,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21831138,PubMed,10.1111/J.1364-3703.2011.00738.X,,sundin@msu.edu,no comments,R. Ryan McNally,2012,,McNally-2012-Genetic characteriza,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2995,PHI:2457,UniProt,D4IBH1,,EAM_2938,,,ATCC 49946 / CCPPB 0273 / Ea273 / 27-3,EAM_2938,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21831138,PubMed,10.1111/J.1364-3703.2011.00738.X,,sundin@msu.edu,no comments,R. Ryan McNally,2012,,McNally-2012-Genetic characteriza,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2996,PHI:2458,UniProt,D4I974,,EAM_1248,,,ATCC 49946 / CCPPB 0273 / Ea273 / 27-3,ydcN,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,XRE transcriptional regulator,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21831138,PubMed,10.1111/J.1364-3703.2011.00738.X,,sundin@msu.edu,no comments,R. Ryan McNally,2012,,McNally-2012-Genetic characteriza,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2997,PHI:2459,UniProt,D4ICB6,,EAM_3066,,,ATCC 49946 / CCPPB 0273 / Ea273 / 27-3,nlpI,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,tetratricopeptide lipoprotein,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21831138,PubMed,10.1111/J.1364-3703.2011.00738.X,,sundin@msu.edu,no comments,R. Ryan McNally,2012,,McNally-2012-Genetic characteriza,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2998,PHI:2464,UniProt,Q58PW8,EMBL,AY906858,,,Ea321,HsvA,c. 60-kb chromosomeal region,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Idared,,,shoot,hrp-associated systemic virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,20565644,PubMed,10.1111/J.1364-3703.2005.00269.X,,svb1@cornell.edu,no comments,Chang-Sik Oh,2005,,Oh-2005-The Hrp pathogenicit,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 2999,PHI:2465,UniProt,Q58PW9,EMBL,AY906858,,,Ea321,HsvB,c. 60-kb chromosomeal region,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Idared,,,shoot,hrp-associated systemic virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,20565644,PubMed,10.1111/J.1364-3703.2005.00269.X,,svb1@cornell.edu,no comments,Chang-Sik Oh,2005,,Oh-2005-The Hrp pathogenicit,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 3000,PHI:2466,UniProt,Q58PX0,EMBL,AY906858,,,Ea321,HsvC,c. 60-kb chromosomeal region,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Idared,,,shoot,hrp-associated systemic virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,20565644,PubMed,10.1111/J.1364-3703.2005.00269.X,,svb1@cornell.edu,no comments,Chang-Sik Oh,2005,,Oh-2005-The Hrp pathogenicit,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 3001,PHI:2464,UniProt,Q58PW8,EMBL,AY906858,,,Ea321,HsvA,c. 60-kb chromosomeal region,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,hrp-associated systemic virulence,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,20565644,PubMed,10.1111/J.1364-3703.2005.00269.X,,svb1@cornell.edu,no comments,Chang-Sik Oh,2005,,Oh-2005-The Hrp pathogenicit,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 3002,PHI:2465,UniProt,Q58PW9,EMBL,AY906858,,,Ea321,HsvB,c. 60-kb chromosomeal region,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,hrp-associated systemic virulence,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,20565644,PubMed,10.1111/J.1364-3703.2005.00269.X,,svb1@cornell.edu,no comments,Chang-Sik Oh,2005,,Oh-2005-The Hrp pathogenicit,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 3003,PHI:2466,UniProt,Q58PX0,EMBL,AY906858,,,Ea321,HsvC,c. 60-kb chromosomeal region,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,hrp-associated systemic virulence,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,20565644,PubMed,10.1111/J.1364-3703.2005.00269.X,,svb1@cornell.edu,no comments,Chang-Sik Oh,2005,,Oh-2005-The Hrp pathogenicit,Batch013,2012-10-12,MC,,,,,,,,,,,,,
,,Record 3004,PHI:2467,UniProt,Q01099,,M92994,,,321,hrpN,,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,translocation of DspA/E into plant cells,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,18705858,PubMed,10.1111/J.1364-3703.2008.00471.X,,svb1@cornell.edu,no comments,Ana M. Bocsanczy,2008,,Bocsanczy-2008-HrpN of Erwinia amyl,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3005,PHI:2468,UniProt,Q46640,,ERWHRPI,,,321,hrpJ,,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,translocation of DspA/E into plant cells,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,18705858,PubMed,10.1111/J.1364-3703.2008.00471.X,,svb1@cornell.edu,no comments,Ana M. Bocsanczy,2008,,Bocsanczy-2008-HrpN of Erwinia amyl,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3006,PHI:2467,UniProt,Q01099,,M92994,,,321,hrpN,,,,,,PHI:2468,552,Erwinia amylovora,,Ea321,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,translocation of DspA/E into plant cells,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,18705858,PubMed,10.1111/J.1364-3703.2008.00471.X,,svb1@cornell.edu,no comments,Ana M. Bocsanczy,2008,,Bocsanczy-2008-HrpN of Erwinia amyl,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3007,PHI:2468,UniProt,Q46640,,ERWHRPI,,,321,hrpJ,,,,,,PHI:2467,552,Erwinia amylovora,,Ea321,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,translocation of DspA/E into plant cells,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,18705858,PubMed,10.1111/J.1364-3703.2008.00471.X,,svb1@cornell.edu,no comments,Ana M. Bocsanczy,2008,,Bocsanczy-2008-HrpN of Erwinia amyl,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3008,PHI:2469,UniProt,Q7WTQ9,,AY307102,,,,AcrB,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),MM106,,,leaf,multidrug efflux pump,,,,reduced virulence,,,,,,,,,,no,tetracycline; norfloxacin; ciprofloxacin; ampicillin; carbenicillin; sodium lauryl sulfate; gentian violet; methylene blue; homidium bromide; phloretin; quercetin; naringenin; cianidanol,tetracycline: CAS:60-54-8; norfloxacin: CAS:70458-96-7; ciprofloxacin: CAS:85721-33-1; ampicillin: CAS:69-53-4; carbenicillin: CAS:4697-36-3; sodium lauryl sulfate: CAS:151-21-3; gentian violet: CAS:548-62-9; methylene blue: CAS:61-73-4; homidium bromide: CAS:1239-45-8; phloretin: CAS:60-82-2; quercetin: CAS:117-39-5; naringenin: CAS:480-41-1; cianidanol: CAS:154-23-4,,,,,gene disruption; gene complementation,,,RP,14714867,PubMed,10.1094/MPMI.2004.17.1.43,,m.ullrich@iu-bremen.de,The AcrAB transport system plays an important role during host plant colonization as a resistance mechanism against plant defense as the mutants are more susceptible to the compunds mentioned in the inducer column,Antje Burse,2004,,Burse_2004_MPMI.2004.17.1,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3009,PHI:2470,UniProt,Q5H4Y2,,YP_199373,,,KACC10331,AroQgamma,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain XKK.12,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Baldo,,,leaf,chorismate mutase,,,shikimate pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20128700,PubMed,10.1094/PHYTO-100-3-0262,,degrassi@icgeb.org,no comments,Giuliano Degrassi,2010,,Degrassi2010_PHYTO-100-3-0262,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3010,PHI:2471,UniProt,Q46631,,X77921,,,,Ams,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),Gala on rootstock MM 106,,,leaf,exopolysaccharides amylovoran,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,19821727,PubMed,10.1094/PHYTO-99-11-1237,,sundin@msu.edu,no comments,Jessica M. Koczan,2009,,Koczan_2009_PHYTO-99-11-1237,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3011,PHI:2471,UniProt,Q46631,,X77921,,,,Ams,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,exopolysaccharides amylovoran,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,19821727,PubMed,10.1094/PHYTO-99-11-1237,,sundin@msu.edu,no comments,Jessica M. Koczan,2009,,Koczan_2009_PHYTO-99-11-1238,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3012,PHI:2472,UniProt,Q46654,,X75079,,,Ea7/74,lsc,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),Gala on rootstock MM 106,,,leaf,exopolysaccharides amylovoran,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,19821727,PubMed,10.1094/PHYTO-99-11-1237,,sundin@msu.edu,no comments,Jessica M. Koczan,2009,,Koczan_2009_PHYTO-99-11-1239,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3013,PHI:2472,UniProt,Q46654,,X75079,,,Ea7/74,lsc,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,exopolysaccharides amylovoran,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,19821727,PubMed,10.1094/PHYTO-99-11-1237,,sundin@msu.edu,no comments,Jessica M. Koczan,2009,,Koczan_2009_PHYTO-99-11-1240,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3014,PHI:2473,UniProt,Q9FD00,,AF282857,,,SS104,hrpx,,,,,,,66269,Pantoea stewartii,66271,subsp. stewartii strain SS104,Stewart's wilt; leaf blight,monocots,4577,Zea mays (related: maize),cv. Seneca Horizon,,,leaf; seedling,regulatory gene; part of the HrpX/HrpY two-component system,,,HrpX/HrpY pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,12650455,PubMed,10.1094/MPMI.2003.16.3.238,,coplin.3@osu.edu,no comments,Massimo Merighi,2003,,Merighi_MPMI.2003.16.3,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3015,PHI:2474,UniProt,E3P6S0,,FJ418778,,,8-1,imd1,,,,,,,5207,Cryptococcus neoformans,235443,H99,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,GTP biosynthesis,,,inosine monophosphate dehydrogenase (IMPDH) pathway,reduced virulence,,,,,,,,reduced,,no,mycophenolic acid (MPA); fluconazole,"mycophenolic acid: CAS:483-60-3; fluconazole: CHEBI:46081, CAS:86386-73-4",,,,,gene disruption; gene complementation,,,RP,23071437,PubMed,10.1371/journal.ppat.1002957,,jafraser@uq.edu.au,no comments,Carl A. Morrow,2012,,Morrow-2012-_italic_De novo__ita,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3016,PHI:2474,UniProt,E3P6S0,,FJ418778,,,8-1,imd1,,,,,,,5207,Cryptococcus neoformans,235443,H99,meningoencephalitis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,lung,GTP biosynthesis,,,inosine monophosphate dehydrogenase (IMPDH) pathway,reduced virulence,,,,,,,,reduced,,no,mycophenolic acid (MPA); fluconazole,"mycophenolic acid: CAS:483-60-3; fluconazole: CHEBI:46081, CAS:86386-73-4",,,,,gene disruption; gene complementation,,,RP,23071437,PubMed,10.1371/journal.ppat.1002957,,jafraser@uq.edu.au,no comments,Carl A. Morrow,2012,,Morrow-2012-_italic_De novo__ita,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3017,PHI:2475,UniProt,Q01099,,M92994,,,321,hrpN,,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,virulence factor secreted via the bacterial type III secretion system,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,18842089,PubMed,10.1094/MPMI-21-11-1387,,twm4@psu.edu,C-terminal half of HrpN plays a specific role in its secretion by the T3SS and in its virulence and avirulence activities,Judith P. Sinn,2008,,Sinn_2008_MPMI-21-11-1387,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3018,PHI:2475,UniProt,Q01099,,M92994,,,321,hrpN,,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,virulence factor secreted via the bacterial type III secretion system,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,18842089,PubMed,10.1094/MPMI-21-11-1387,,twm4@psu.edu,C-terminal half of HrpN plays a specific role in its secretion by the T3SS and in its virulence and avirulence activities,Judith P. Sinn,2008,,Sinn_2008_MPMI-21-11-1387,Batch014,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3019,PHI:2476,UniProt,G8AA67,,GU206360,,,US-41,CcpelA,,,,,,,27358,Colletotrichum coccodes,27358,US-41,anthracnose,eudicots,4081,Solanum lycopersicum (related: tomato),cv. 1402,,,fruit,pectate lyase,,,,reduced virulence,,,,yes,lesions,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,21848609,PubMed,10.1111/J.1364-3703.2011.00740.X,,barzvi@bgu.ac.il,no comments,Bat-Hen Ben-Daniel,2012,,Ben-Daniel-2012-Pectate lyase affect,Batch007a,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3020,PHI:2476,UniProt,G8AA67,,GU206361,,,Si-60,CcpelA,,,,,,,27358,Colletotrichum coccodes,27358,Si-60,anthracnose,eudicots,4081,Solanum lycopersicum (related: tomato),cv. 1402,,,fruit,pectate lyase,,,,increased virulence (hypervirulence),,,,,lesions,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,21848609,PubMed,10.1111/J.1364-3703.2011.00740.X,,barzvi@bgu.ac.il,no comments,Bat-Hen Ben-Daniel,2012,,Ben-Daniel-2012-Pectate lyase affect,Batch007a,2012-10-23,MC,,,,,,,,,,,,,
,,Record 3021,PHI:2477,UniProt,B8QZV4,,EU770253; EU746409,,,,CYP1,,,,,,,5116,Cryphonectria parasitica,660469,EP155,blight (chestnut),eudicots,60419,Castanea mollissima (related: chinese chestnut),,,,stem,cyclophilin A-encoding gene,,,G-protein signal transduction,reduced virulence,,,,,smaller lesions,wild type,,wild type,wild type,no,cyclosporine,cyclosporine: CAS:59865-13-3,,,,,gene deletion: full; gene complementation,,,RP,21355996,PubMed,10.1111/J.1364-3703.2010.00665.X,,chenyaoj@gxu.edu.cn,Dcyp1 strain was highly tolerant to CsA,Min-Mei Chen,2011,,"Chen-2011-CYP1, a hypovirus-re",Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3022,PHI:2478,UniProt,D6BK26,,EU707808,,,SL2029,rsa1,,,,,,,305,Ralstonia solanacearum,,SL341,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. Nockwang,,,leaf,aspartic protease,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,RP,21453432,PubMed,10.1111/J.1364-3703.2010.00679.X,,ingyu@snu.ac.kr,no comments,Yeonhwa Jeong,2011,,Jeong-2011-An HrpB-dependent bu,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3023,PHI:2478,UniProt,D6BK26,,EU707808,,,SL2029,rsa1,,,,,,,305,Ralstonia solanacearum,,SL2029,bacterial wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. Daeji,,,leaf,aspartic protease,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,RP,21453432,PubMed,10.1111/J.1364-3703.2010.00679.X,,ingyu@snu.ac.kr,no comments,Yeonhwa Jeong,2011,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3024,PHI:2478,UniProt,D6BK26,,EU707808,,,SL2029,rsa1,,,,,,,305,Ralstonia solanacearum,,SL341,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Kwang-Soo,,,leaf,aspartic protease,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,RP,21453432,PubMed,10.1111/J.1364-3703.2010.00679.X,,ingyu@snu.ac.kr,no comments,Yeonhwa Jeong,2011,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3025,PHI:2478,UniProt,D6BK26,,EU707808,,,SL2029,rsa1,,,,,,,305,Ralstonia solanacearum,,SL2029,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Kwang-Soo,,,leaf,aspartic protease,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,RP,21453432,PubMed,10.1111/J.1364-3703.2010.00679.X,,ingyu@snu.ac.kr,no comments,Yeonhwa Jeong,2011,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3026,PHI:2479,UniProt,E1AP33,,HM852064,,,Ecc71,corA,,,,,,,554,Pectobacterium carotovorum,,KD100,soft rot,eudicots,4045,Apium graveolens (no common name found),dulce group,,,petiole,magnesium/nickel/cobalt transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,21726393,PubMed,10.1111/J.1364-3703.2011.00726.X,,cdumenyo@tnstate.edu,no comments,Caleb M. Kersey,2012,,"Kersey-2012-CorA, the magnesium_",Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3027,PHI:2479,UniProt,E1AP33,,HM852064,,,Ecc71,corA,,,,,,,554,Pectobacterium carotovorum,555,subsp. carotovorum strain Ecc71,soft rot,eudicots,4045,Apium graveolens (no common name found),dulce group,,,petiole,magnesium/nickel/cobalt transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,21726393,PubMed,10.1111/J.1364-3703.2011.00726.X,,cdumenyo@tnstate.edu,no comments,Caleb M. Kersey,2012,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3028,PHI:2479,UniProt,E1AP33,,HM852064,,,Ecc71,corA,,,,,,,554,Pectobacterium carotovorum,,KD100,soft rot,eudicots,4039,Daucus carota (related: carrot),,,,root,magnesium/nickel/cobalt transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,21726393,PubMed,10.1111/J.1364-3703.2011.00726.X,,cdumenyo@tnstate.edu,no comments,Caleb M. Kersey,2012,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3029,PHI:2479,UniProt,E1AP33,,HM852064,,,Ecc71,corA,,,,,,,554,Pectobacterium carotovorum,555,subsp. carotovorum strain Ecc71,soft rot,eudicots,4039,Daucus carota (related: carrot),,,,root,magnesium/nickel/cobalt transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,21726393,PubMed,10.1111/J.1364-3703.2011.00726.X,,cdumenyo@tnstate.edu,no comments,Caleb M. Kersey,2012,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3030,PHI:2480,UniProt,Q8PGM0,,XAC3596,,,306,wxacO,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,leaf,putative transmembrane protein,,,,reduced virulence,,,,,,,,reduced,,no,sodium chloride; sorbitol; hydrogen peroxide; polymyxin B,sodium chloride: CAS:7647-14-5; sorbitol: CAS:50-70-4; hydrogen peroxide: CAS:7722-84-1; polymyxin B: CAS:1404-26-8,,,,,gene disruption; gene complementation,,,RP,21453433,PubMed,10.1111/J.1364-3703.2010.00681.X,,nianwang@crec.ifas.ufl.edu,Mutants more sensitive to various stresses,Jinyun Li,2011,,Li-2011-The wxacO gene of Xa,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3031,PHI:2481,UniProt,Q8PGL8,,XAC3598,,,306,rfbC,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,leaf,O-antigen biosynthesis protein [truncated],,,,reduced virulence,,,,,,,,reduced,,no,sodium chloride; sorbitol; hydrogen peroxide; polymyxin B,sodium chloride: CAS:7647-14-5; sorbitol: CAS:50-70-4; hydrogen peroxide: CAS:7722-84-1; polymyxin B: CAS:1404-26-8,,,,,gene disruption; gene complementation,,,RP,21453433,PubMed,10.1111/J.1364-3703.2010.00681.X,,nianwang@crec.ifas.ufl.edu,Mutants more sensitive to various stresses,Jinyun Li,2011,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3032,PHI:2482,UniProt,Q09JB7,,DQ887541,,,K-10,AlHK1,,,,,,,160389,Alternaria longipes,,C-00,brown spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. K326,,,leaf,group III two-component histidine kinase,,,,increased virulence (hypervirulence),,,yes,,,reduced,,wild type,,no,"N-(3,5-dichlorophenyl)succinimide [dim]; fludioxonil [flu]; quintozene [PCNB]; sodium chloride; potassium chloride; sorbitol; glucose","N-(3,5-dichlorophenyl)succinimide: CAS:93196-73-7; fludioxonil: CAS:86386-73-4; quintozene: CAS:82-68-8; sodium chloride: CAS:7647-14-5; potassium chloride: CAS:7447-40-7; sorbitol: CAS:50-70-4; glucose: CAS:50-99-7",,,,,gene deletion: full,,,RP,22349956,PubMed,10.1007/s00284-012-0093-8,,yyongl_168@yahoo.com.cn,"Resistance of the mutants to the fungicides is the same as wildtype i.e. resistant to dicarboximide, phenylpyrrole and aromatic hydrocarbon fungicides; mutants more sensitive to osmotic stress",Yi Yong Luo,2012,,Luo-2012-The group III two-co,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3033,PHI:2482,UniProt,Q09JB7,,DQ887541,,,K-10,AlHK1,,,,,,,160389,Alternaria longipes,,C-00,brown spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Honghuadajinyuan,,,leaf,group III two-component histidine kinase,,,,increased virulence (hypervirulence),,,yes,,,reduced,,wild type,,no,"N-(3,5-dichlorophenyl)succinimide [dim]; fludioxonil [flu]; quintozene [PCNB]; sodium chloride; potassium chloride; sorbitol; glucose","N-(3,5-dichlorophenyl)succinimide: CAS:93196-73-7; fludioxonil: CAS:86386-73-4; quintozene: CAS:82-68-8; sodium chloride: CAS:7647-14-5; potassium chloride: CAS:7447-40-7; sorbitol: CAS:50-70-4; glucose: CAS:50-99-7",,,,,gene deletion: full,,,RP,22349956,PubMed,10.1007/s00284-012-0093-8,,yyongl_168@yahoo.com.cn,"Resistance of the mutants to the fungicides is the same as wildtype i.e. resistant to dicarboximide, phenylpyrrole and aromatic hydrocarbon fungicides; mutants more sensitive to osmotic stress",Yi Yong Luo,2012,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3034,PHI:2483,UniProt,A6SEF3,,CH476921,,,B05.10,BcCCC2,,,,,,,40559,Botrytis cinerea,,HYOGO11,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,copper-transporting ATPase,,,,loss of pathogenicity,,yes,yes,yes,,reduced,,wild type; aberrant,,no,copper,copper: CAS:7440-50-8,,,,,gene deletion: full; gene complementation,,,RP,20526618,PubMed,10.1007/s00438-010-0545-4,,chihiro@kais.kyoto-u.ac.jp,Copper restored some of the mutant defects like conidiation,Yoshimoto Saitoh,2010,,Saitoh-2010-A copper-transportin,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3035,PHI:2483,UniProt,A6SEF3,,CH476921,,,B05.10,BcCCC2,,,,,,,40559,Botrytis cinerea,,HYOGO11,grey mold,eudicots,3570,Dianthus caryophyllus (related: clove pink),,,,petal,copper-transporting ATPase,,,,loss of pathogenicity,,yes,yes,yes,,reduced,,wild type; aberrant,,no,copper,copper: CAS:7440-50-8,,,,,gene deletion: full; gene complementation,,,RP,20526618,PubMed,10.1007/s00438-010-0545-4,,chihiro@kais.kyoto-u.ac.jp,Copper restored some of the mutant defects like conidiation,Yoshimoto Saitoh,2010,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3036,PHI:2484,UniProt,B6VCT9,,FJ374679,,,,Ste11,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,MAP triple kinase,,,MAPK pathway,loss of pathogenicity,,yes,yes,yes,small necrotic lesions,aberrant,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,20078780,PubMed,10.1111/J.1364-3703.2009.00579.X,,hahn@rhrk.uni-kl.de,no comments,Astrid Schamber,2010,,Schamber-2010-The role of mitogen-,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3037,PHI:2485,UniProt,A6RT73,,EDN20614,,,B05.10,Ste7,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,MAP kinase kinas,,,MAPK pathway,loss of pathogenicity,,yes,yes,yes,small necrotic lesions,aberrant,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,20078780,PubMed,10.1111/J.1364-3703.2009.00579.X,,hahn@rhrk.uni-kl.de,no comments,Astrid Schamber,2010,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3038,PHI:2486,UniProt,A6S3X7,,EDN27521,,,B05.10,Ste50,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,MAP kinase adaptor protein,,,MAPK pathway,loss of pathogenicity,,yes,yes,yes,small necrotic lesions,aberrant,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,20078780,PubMed,10.1111/J.1364-3703.2009.00579.X,,hahn@rhrk.uni-kl.de,no comments,Astrid Schamber,2010,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3039,PHI:2487,UniProt,B6VCT8,,FJ374678,,,,ste12,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,transcription factor,,,MAPK pathway,reduced virulence,,,yes,,,,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,20078780,PubMed,10.1111/J.1364-3703.2009.00579.X,,hahn@rhrk.uni-kl.de,no comments,Astrid Schamber,2010,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3040,PHI:2487,UniProt,B6VCT8,,FJ374678,,,,ste12,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,transcription factor,,,MAPK pathway,reduced virulence,,,,,,,,,reduced,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,20078780,PubMed,10.1111/J.1364-3703.2009.00579.X,,hahn@rhrk.uni-kl.de,no comments,Astrid Schamber,2010,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3041,PHI:2484,UniProt,B6VCT9,,FJ374679,,,,Ste11,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,MAP triple kinase,,,MAPK pathway,loss of pathogenicity,,yes,yes,yes,small necrotic lesions,aberrant,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,20078780,PubMed,10.1111/J.1364-3703.2009.00579.X,,hahn@rhrk.uni-kl.de,no comments,Astrid Schamber,2010,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3042,PHI:2485,UniProt,A6RT73,,EDN20614,,,B05.10,Ste7,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,MAP kinase kinas,,,MAPK pathway,loss of pathogenicity,,yes,yes,yes,small necrotic lesions,aberrant,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,20078780,PubMed,10.1111/J.1364-3703.2009.00579.X,,hahn@rhrk.uni-kl.de,no comments,Astrid Schamber,2010,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3043,PHI:2486,UniProt,A6S3X7,,EDN27521,,,B05.10,Ste50,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,MAP kinase adaptor protein,,,MAPK pathway,loss of pathogenicity,,yes,yes,yes,small necrotic lesions,aberrant,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,20078780,PubMed,10.1111/J.1364-3703.2009.00579.X,,hahn@rhrk.uni-kl.de,no comments,Astrid Schamber,2010,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3044,PHI:2487,UniProt,B6VCT8,,FJ374678,,,,ste12,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,transcription factor,,,MAPK pathway,reduced virulence,,,yes,,,,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,20078780,PubMed,10.1111/J.1364-3703.2009.00579.X,,hahn@rhrk.uni-kl.de,no comments,Astrid Schamber,2010,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3045,PHI:2487,UniProt,B6VCT8,,FJ374678,,,,ste12,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,transcription factor,,,MAPK pathway,reduced virulence,,,,,,,,,reduced,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,20078780,PubMed,10.1111/J.1364-3703.2009.00579.X,,hahn@rhrk.uni-kl.de,no comments,Astrid Schamber,2010,,,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3046,PHI:2488,UniProt,G4ND25,,MGG_00994.6,,,70-15,Man1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,"a-1,2-mannosidase",,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,19621226,PubMed,10.1007/s00294-009-0261-y,,guodonglu@yahoo.com,no comments,Jie Zhou,2009,,Zhou-2009-Functional analysis,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3047,PHI:2489,UniProt,E2J5T5,,HM988729,,,13751,rsmAXoo,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain 13751,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Teyou 63,,,leaf,RNA-binding protein,,,,loss of pathogenicity,,,,yes,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,21355995,PubMed,10.1111/J.1364-3703.2010.00661.X,,jiaxunfeng@sohu.com,no comments,Pei-Liang Zhu,2011,,Zhu-2011-The rsmA-like gene r,Batch015,2012-10-31,MC,,,,,,,,,,,,,
,,Record 3048,PHI:2490,UniProt,E9B636,,LmxM.34.1580,,,MHOM/GT/2001/U1103,MCA,,,,,,,5665,Leishmania mexicana,,MNYC/BZ/62/M379,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,foot,"metacaspase; cell death; cell cycle control, differentiation and clearance of aggregates",,,cell death pathway,increased virulence (hypervirulence),,,,,,,,increased,,no,miltefosine; camptothecin,"miltefosine: CAS:58066-85-6, 4",,,,,gene deletion: full; gene complementation,,,RP,22951982,PubMed,10.1038/cddis.2012.113,,jeremy.mottram@gla sgow.ac.uk,Delta mca were less susceptible to MLF-induced cell death. Footpad.,E Castanys-Munoz,2012,,Castanys-Munoz-2012-Leishmania mexicana,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3049,PHI:2490,UniProt,E9B636,,LmxM.34.1580,,,MHOM/GT/2001/U1103,MCA,,,,,,,5665,Leishmania mexicana,,MNYC/BZ/62/M379,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,foot,"metacaspase; cell death; cell cycle control, differentiation and clearance of aggregates",,,cell death pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,22951982,PubMed,10.1038/cddis.2012.113,,jeremy.mottram@gla sgow.ac.uk,Footpad.,E Castanys-Munoz,2012,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3050,PHI:2491,UniProt,I1RJS9,,FGSG_04111,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FgPTC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),,,,coleoptile,type 2C protein phosphatase,,,,reduced virulence,,,,,,wild type,,reduced,,no,lithium,CAS:17341-24-1,,,,,gene deletion: full; gene complementation,,,RP,20447276,PubMed,10.1111/J.1364-3703.2009.00598.X,,linghuojiang2@yahoo.com.cn,Deletion of FgPTC1 delays the mycelium growth of F. graminearum in response to lithium,Linghuo Jiang,2010,,Jiang-2010-The type 2C protein,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3051,PHI:2492,UniProt,Q8XVQ5,,AL646052,,,GMI1000,PopW,,,,,,,305,Ralstonia solanacearum,,ZJ3721,,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Shanghai 903,,,leaf,harpin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,20447285,PubMed,10.1111/J.1364-3703.2010.00610.X,,jhguo@njau.edu.cn,no comments,Jian-Gang Li,2010,,Li-2010-PopW of Ralstonia so,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3052,PHI:2493,UniProt,Q4UY34,,XC0965,,,8004,XC0965,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot (Cruciferae),eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,"cyclic di-GMP binding protein domain; proteins with this domain are involved in regulation of specific cellular processes, including the virulence of animal pathogens",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,19019010,PubMed,10.1111/J.1364-3703.2008.00495.X,,m.dow@ucc.ie,no comments,Yvonne Mc Carthy,2008,,McCarthy-2008-The role of PilZ dom,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3053,PHI:2494,UniProt,Q4UUG9,,XC2249,,,8004,XC2249,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot (Cruciferae),eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,"cyclic di-GMP binding protein domain; proteins with this domain are involved in regulation of specific cellular processes, including the virulence of animal pathogens",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,19019010,PubMed,10.1111/J.1364-3703.2008.00495.X,,m.dow@ucc.ie,no comments,Yvonne Mc Carthy,2008,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3054,PHI:2495,UniProt,Q4UUA3,,XC2317,,,8004,XC2317,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot (Cruciferae),eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,"cyclic di-GMP binding protein domain; proteins with this domain are involved in regulation of specific cellular processes, including the virulence of animal pathogens",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,19019010,PubMed,10.1111/J.1364-3703.2008.00495.X,,m.dow@ucc.ie,no comments,Yvonne Mc Carthy,2008,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3055,PHI:2496,UniProt,Q4URQ8,,XC3221,,,8004,XC3221,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot (Cruciferae),eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,"cyclic di-GMP binding protein domain; proteins with this domain are involved in regulation of specific cellular processes, including the virulence of animal pathogens",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,19019010,PubMed,10.1111/J.1364-3703.2008.00495.X,,m.dow@ucc.ie,no comments,Yvonne Mc Carthy,2008,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3056,PHI:2497,UniProt,Q4P2U6,,um05567,,,521 / FGSC 9021,atg8,,,,,,,5270,Ustilago maydis,237631,521,smut (maize),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf; corn ear,autophagy,,,,reduced virulence,no,,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,20618705,PubMed,10.1111/J.1364-3703.2010.00620.X,,sgold@uga.edu,no comments,Marina Nadal,2010,,Nadal-2010-The autophagy genes,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3057,PHI:2498,UniProt,Q4P0K0,,um06363,,,521 / FGSC 9021,atg1,,,,,,,5270,Ustilago maydis,237631,521,smut (maize),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf; corn ear,autophagy,,,,reduced virulence,no,,,,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,20618705,PubMed,10.1111/J.1364-3703.2010.00620.X,,sgold@uga.edu,no comments,Marina Nadal,2010,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3058,PHI:2497,UniProt,Q4P2U6,,um05567,,,521 / FGSC 9021,atg8,,,,,,PHI:2498,5270,Ustilago maydis,237631,521,smut (maize),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf; corn ear,autophagy,,,,loss of pathogenicity,no,,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,20618705,PubMed,10.1111/J.1364-3703.2010.00620.X,,sgold@uga.edu,no comments,Marina Nadal,2010,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3059,PHI:2498,UniProt,Q4P0K0,,um06363,,,521 / FGSC 9021,atg1,,,,,,PHI:2497,5270,Ustilago maydis,237631,521,smut (maize),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf; corn ear,autophagy,,,,loss of pathogenicity,no,,,,,,,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,20618705,PubMed,10.1111/J.1364-3703.2010.00620.X,,sgold@uga.edu,no comments,Marina Nadal,2010,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3060,PHI:2499,UniProt,P96320,,Y09848,,,Ea1/79,rcsB,,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,phosphorelay system,,,,loss of pathogenicity,,,,yes,,,,,,no,polymyxin B,CAS:1404-26-8,,,,,gene disruption; gene complementation,,,RP,19236575,PubMed,10.1111/J.1364-3703.2008.00531.X,,zhao888@illinois.edu,"Rcs mutants were more susceptible to polymyxin B treatment than the wild-type, suggesting that the Rcs system conferred some level of resistance to polymyxin B",Dongping Wang,2009,,Wang-2009-The Rcs phosphorelay,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3061,PHI:2500,UniProt,D4I7B7,,FN666575,,,ATCC 49946,rcsC,,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,phosphorelay system,,,,loss of pathogenicity,,,,yes,,,,,,no,polymyxin B,CAS:1404-26-8,,,,,gene disruption; gene complementation,,,RP,19236575,PubMed,10.1111/J.1364-3703.2008.00531.X,,zhao888@illinois.edu,"Rcs mutants were more susceptible to polymyxin B treatment than the wild-type, suggesting that the Rcs system conferred some level of resistance to polymyxin B",Dongping Wang,2009,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3062,PHI:2501,UniProt,D4HWX6,,FN434113,,,CFPB1430,rcsD,,,,,,,552,Erwinia amylovora,,Ea321,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,phosphorelay system,,,,loss of pathogenicity,,,,yes,,,,,,no,polymyxin B,CAS:1404-26-8,,,,,gene disruption; gene complementation,,,RP,19236575,PubMed,10.1111/J.1364-3703.2008.00531.X,,zhao888@illinois.edu,"Rcs mutants were more susceptible to polymyxin B treatment than the wild-type, suggesting that the Rcs system conferred some level of resistance to polymyxin B",Dongping Wang,2009,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3063,PHI:2499,UniProt,P96320,,Y09848,,,Ea1/79,rcsB,,,,,,PHI:2501,552,Erwinia amylovora,,Ea321,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,phosphorelay system,,,,loss of pathogenicity,,,,yes,,,,,,no,polymyxin B,CAS:1404-26-8,,,,,gene disruption; gene complementation,,,RP,19236575,PubMed,10.1111/J.1364-3703.2008.00531.X,,zhao888@illinois.edu,"Rcs mutants were more susceptible to polymyxin B treatment than the wild-type, suggesting that the Rcs system conferred some level of resistance to polymyxin B",Dongping Wang,2009,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3064,PHI:2501,UniProt,D4HWX6,,FN434113,,,CFPB1430,rcsD,,,,,,PHI:2499,552,Erwinia amylovora,,Ea321,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,phosphorelay system,,,,loss of pathogenicity,,,,yes,,,,,,no,polymyxin B,CAS:1404-26-8,,,,,gene disruption; gene complementation,,,RP,19236575,PubMed,10.1111/J.1364-3703.2008.00531.X,,zhao888@illinois.edu,"Rcs mutants were more susceptible to polymyxin B treatment than the wild-type, suggesting that the Rcs system conferred some level of resistance to polymyxin B",Dongping Wang,2009,,,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3065,PHI:2502,UniProt,I1RM09,,FGSG_04982.3,,,PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084,FgTep1p,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4564,Triticum (related: wheat),cv. Chinese Spring,,,coleoptile,,,,PI3K pathway,reduced virulence,,,,,,reduced,,wild type,wild type,no,lithium chloride; wortmannin,lithium chloride: CAS:7447-41-8; wortmannin: CAS:19545-26-7,,,,,gene disruption; gene complementation,,,RP,20618707,PubMed,10.1111/J.1364-3703.2010.00626.X,,linghuojiang2@yahoo.com.cn,"Deletion of FgTEP1 causes F. graminearum mycelial growth to become sen-sitive to lithium and reduces the production of conidia / conidia lacking FgTEP1 germinate normally, they show reduced germination efficiency in the presence of wortmannin",Dajun Zhang,2010,,Zhang-2010-FgTep1p is linked to,Batch016,2012-11-09,MC,,,,,,,,,,,,,
,,Record 3066,PHI:2503,UniProt,Q96UQ6,,AF435120,,,,AGS1,,,,,,,746128,Aspergillus fumigatus,,CBS 144.89,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),SWR,,,lung,"putative alpha-1,3-glucan synthase",,,,unaffected pathogenicity,,,,,,reduced,,wild type; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,15746357,PubMed,10.1128/AEM.71.3.1531-1538.2005,,abeauvai@pasteur.fr.,no comments,A. Beauvais,2005,,2005-Two alpha(1-3) gluca,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3067,PHI:2504,UniProt,Q96UR0,,AF432352,,,,AGS2,,,,,,,746128,Aspergillus fumigatus,,CBS 144.89,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),SWR,,,lung,"putative alpha-1,3-glucan synthase",,,,unaffected pathogenicity,,,,,,reduced,,wild type; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,15746357,PubMed,10.1128/AEM.71.3.1531-1538.2005,,abeauvai@pasteur.fr.,no comments,A. Beauvais,2005,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3068,PHI:2505,,no data found,GenBank,AB04090.1,,,ATCC 96836,AbPacC,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,putative transcription factor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23133370,PubMed,10.1371/journal.ppat.1002974,,yangrae@hawaii.edu,"Seeds purchased from commercial grower: Johnny's Selected Seeds (Winslow, Maine)",Yangrae Cho,2012,,Cho-2012-Transcription Factor,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3069,PHI:2506,UniProt,G3F820,GenBank,JF487829,,,ATCC 96836,Amr1,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,putative transcription factor,,,melanin biosynthesis pathway,increased virulence (hypervirulence),,,,,,wild type; aberrant,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,23133370,PubMed,10.1371/journal.ppat.1002974,,yangrae@hawaii.edu,"Seeds purchased from commercial grower: Johnny's Selected Seeds (Winslow, Maine)",Yangrae Cho,2012,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3070,PHI:2507,,no data found,GenBank,AB10176.1,,,ATCC 96836,AbVf8,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,pathogenesis associated transcription factor,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,23133370,PubMed,10.1371/journal.ppat.1002974,,yangrae@hawaii.edu,"Seeds purchased from commercial grower: Johnny's Selected Seeds (Winslow, Maine)",Yangrae Cho,2012,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3071,PHI:2508,,no data found,GenBank,AB02277.1,,,ATCC 96836,abpks7,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,"produces a melanin-intermediate product, 1,3,6,8-tetrahy-droxynaphthalene (T4HN)",,,melanin biosynthesis pathway,unaffected pathogenicity,,,,,,aberrant,,,,no,,,,,,,gene disruption,,,RP,23133370,PubMed,10.1371/journal.ppat.1002974,,yangrae@hawaii.edu,"Seeds purchased from commercial grower: Johnny's Selected Seeds (Winslow, Maine)",Yangrae Cho,2012,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3072,PHI:2509,UniProt,Q4WJ81,,Afu1g06900,,,Af293,CrzA,,,,,,,746128,Aspergillus fumigatus,330879,AF293.1,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,C2H2 transcription factor,,,calcineurin pathway,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,reduced,no,caspofungin; nikkomycin; tacrolimus [FK506],caspofungin: CAS:162808-62-0; nikkomycin: CAS:59456-70-1; tacrolimus: CAS:104987-11-3,,,,,gene deletion: full; gene complementation,,,RP,18456861,PubMed,10.1128/EC.00086-08,,stein022@mc.duke.edu,Cell wall inhibitors inhibit hyphal growth in calcineurin pathway mutants,Robert A. Cramer,2008,,Eukaryotic_Cell-2008-Cramer-1085-97,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3073,PHI:2510,UniProt,Q6PWQ1,,AY573554,,,YJ-407,msdS/AfmsdC,chromosome 2,,,,,,746128,Aspergillus fumigatus,,YJ-407,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,a-mannosidases,,,,unaffected pathogenicity,,,,,,reduced; aberrant,,wild type; aberrant,wild type; aberrant,no,7-diethylamino-4-methylcoumarin; Congo red,7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0,,,,,gene deletion: full; gene complementation,,,RP,18599824,PubMed,10.1099/mic.0.2008/017525-0,,jinc@sun.im.ac.cn,Mutant showed a slightly increased sensitivity to Calcofluo r white and Congo red at 50C,Yanjie Li,2008,,Li Microbiology 2008 Deletion of the msdS_AfmsdC gene induces abnormal polarity and septation in Aspergillus fumigatus,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3074,PHI:2511,UniProt,Q4WT66,,EAL90366,,,Af293,Pes1,,,,,,,746128,Aspergillus fumigatus,330879,293.1,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),ATCC 26933,,,larva,nonribosomal peptide synthetase gene,,,,reduced virulence,,,,,,aberrant,,,,no,hypochlorous acid [HOCl]; hydrogen peroxide,hypochlorous acid: CAS:7790-92-3; hydrogen peroxide: CAS:7722-84-1,,,,,gene disruption,,,RP,16759234,PubMed,10.1111/j.1742-4658.2006.05315.x,,sean.doyle@nuim.ie,Increased sensitivity to oxidative stress,Emer P. Reeves,2006,,Reeves-2006-A nonribosomal pepti,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3075,PHI:2512,UniProt,Q4WER3,,Afu5g03920,,,Af293,HapX,,,,,,,746128,Aspergillus fumigatus,330879,293.1,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),leucopenic and non-leucopenic mouse models,,,lung,bZip-type regulator involved in adaption to iron starvation,,,iron-dependent pathways,reduced virulence,,,,,,wild type,,wild type,wild type,no,"tetracycline; zinc, elemental; bathophenanthroline disulfonic acid","tetracycline: CAS:60-54-8; zinc,  elemental: CAS:7440-66-6; bathophenanthroline disulfonic acid: CAS:28061-20-3",,,,,gene disruption; gene complementation,,,RP,20941352,PubMed,10.1371/journal.ppat.1001124,,hubertus.haas@i-me d.ac.a,"Iron depleted medium caused reduction in germination, growth, conidiation and virulence./ Sensitivity of mutants increased with trtracycline and zinc",Markus Schrettl,2010,,Schrettl-2010-HapX-mediated adapti,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3076,PHI:2513,UniProt,E9R5E2,GenBank,XP_750525,,,Af293,GFA1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,glutamine-fructose-6-phosphate aminotransferase,,,chitin biosynthesis pathway,lethal,,,,,,aberrant,,,reduced,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,Hu-2007-Essential gene ident,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3077,PHI:2514,UniProt,Q4X1Y0,GenBank,XP_755173.1,,,Af293,PFS2,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3078,PHI:2515,UniProt,Q4X146,GenBank,XP_755457,,,Af293,ALG7,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,UDP-N-acetyl-glucosamine-1-P transferase,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3079,PHI:2516,UniProt,Q4WDG8,GenBank,XP_747608,,,Af293,HIS3,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,imidazole-glycerol-phosphate dehydratase,,,amino acid biosynthesis,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3080,PHI:2517,UniProt,Q4X0J6,GenBank,XP_755657,,,Af293,TRPS,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,tryptophan synthase,,,amino acid biosynthesis,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3081,PHI:2518,UniProt,Q4WWN9,GenBank,XP_754952,,,Af293,MET16,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,3'-phospho-adenylylsulfate reductase,,,amino acid biosynthesis,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3082,PHI:2519,UniProt,Q4WQ27,GenBank,XP_751695,,,Af293,LYS9,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,saccharopine dehydrogenase,,,amino acid biosynthesis,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3083,PHI:2520,UniProt,Q4WUL6,GenBank,XP_753748,,,Af293,LYS4,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,homoaconitate hydratase,,,amino acid biosynthesis,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3084,PHI:2521,UniProt,Q4WEM7,GenBank,XP_747988,,,Af293,GUS1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,glutamate-tRNA sythetase,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3085,PHI:2522,UniProt,Q4WEN8,GenBank,XP_747977,,,Af293,SPE2,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,S-adenosyl-methionine decarboxylase,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3086,PHI:2524,UniProt,Q70ZY8,GenBank,XP_750605.1,,,Af293,nudC,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,,,,,lethal,,,,,,aberrant,,,reduced; defective,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3087,PHI:2525,UniProt,Q4WDL0,GenBank,XP_747566,,,Af293,TOM40,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,mitochondrial import receptor subunit,,,,lethal,,,,,,,,,,yes,,,,,,,gene disruption,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3088,PHI:2526,UniProt,Q4WMR3,GenBank,XP_750789,,,Af293,LUC7,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,U1 snRNA-associated protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene disruption,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3089,PHI:2525,UniProt,Q4WDL0,GenBank,XP_747566,,,Af293,TOM40,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,mitochondrial import receptor subunit,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3090,PHI:2526,UniProt,Q4WMR3,GenBank,XP_750789,,,Af293,LUC7,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,U1 snRNA-associated protein,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3091,PHI:2527,UniProt,Q4X0M4,GenBank,XP_755629,,,Af293,SEC31,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,initiation of germ tubes,,,,lethal,,,,,,,,,reduced,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3092,PHI:2528,UniProt,Q4WYU7,GenBank,XP_754194,,,Af293,SLY1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,initiation of germ tubes,,,,lethal,,,,,,,,,reduced,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3093,PHI:2529,UniProt,Q4WCL5,GenBank,XP_747207,,,Af293,ERG10,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,acetyl-CoA acetyl-transferase,,,,lethal,,,,,,,,,reduced,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3094,PHI:2530,UniProt,Q4WKG5,GenBank,XP_750005,,,Af293,TUB1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,tubulin alpha-1 chain,,,,lethal,,,,,,,,,reduced,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3095,PHI:2531,UniProt,Q4WXC5,GenBank,XP_754716,,,Af293,PRI1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,DNA primase small subunit,,,,lethal,,,,,,,,,reduced,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3096,PHI:2532,UniProt,Q4WUA3,GenBank,XP_753861,,,Af293,HEM15,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,ferrochelatase,,,,lethal,,,,,,aberrant,,,aberrant,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3097,PHI:2533,UniProt,Q4WLT4,GenBank,XP_751118,,,Af293,FKS1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,"beta 1,3 glucan synthase",,,,lethal,,,,,,,,,aberrant,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3098,PHI:2534,UniProt,Q4WNT5,GenBank,XP_752137,,,Af293,ERG11A,,,,,,PHI:2535,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,14 alpha-demethylase,,,,lethal,,,,,,,,,,no,,,,,,,gene disruption,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,"Either of the ERG11 gene pair can functionally compensate for loss of the other, and the genetic inactivation of both ERG11A and ERG11B indicates their essentiality in A. fumigatus .",Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3099,PHI:2535,UniProt,E9QY26,GenBank,XP_749134.1,,,Af293,ERG11B,,,,,,PHI:2534,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,14 alpha-demethylase,,,,lethal,,,,,,,,,,no,,,,,,,gene disruption,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,"Either of the ERG11 gene pair can functionally compensate for loss of the other, and the genetic inactivation of both ERG11A and ERG11B indicates their essentiality in A. fumigatus .",Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3100,PHI:2536,UniProt,Q4WU51,GenBank,XP_753913,,,Af293,MET2,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,homoserine O-acetyl-transferase,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3101,PHI:2537,UniProt,Q4WQJ0,GenBank,XP_751532,,,Af293,TRR1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,thioredoxin reductase,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3102,PHI:2538,UniProt,Q4WXL8,GenBank,XP_754623,,,Af293,AUR1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,phosphatidyl-inositol:ceramide phosphoinositol transferase,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3103,PHI:2539,UniProt,Q4WJ71,GenBank,XP_750449,,,Af293,CDS1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,CDP-diacyl glycerol synthase,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3104,PHI:2540,UniProt,Q4WX65,GenBank,XP_754776,,,Af293,IPP1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,inorganic pyrophosphatase,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3105,PHI:2541,UniProt,Q4WGR1,GenBank,XP_748918,,,Af293,OLE1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,stearoyl-CoA desaturase,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3106,PHI:2542,UniProt,Q4WP25,GenBank,XP_752047,,,Af293,ERG12,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,mavalonate kinase,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3107,PHI:2543,UniProt,Q4WLS1,GenBank,XP_751131,,,Af293,GCD6,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,translation initiation factor eIF2B,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3108,PHI:2544,UniProt,Q4WK03,GenBank,XP_750167,,,Af293,PAB1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,poly(A)-binding protein of cytoplasm and nucleus,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3109,PHI:2545,UniProt,Q4X1I3,GenBank,XP_755320,,,Af293,TIF35,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,translation initiation factor eIF3,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3110,PHI:2546,UniProt,Q4WKJ9,GenBank,XP_749971,,,Af293,BRX1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,protein required for rRNA maturation,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3111,PHI:2547,UniProt,Q4WHH1,GenBank,XP_749672,,,Af293,ESF1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,protein required for 18S rRNA biogenesis,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3112,PHI:2548,UniProt,Q4X132,GenBank,XP_755471,,,Af293,KRR1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,component of 90S preribosomal particles,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3113,PHI:2549,UniProt,Q4WMS3,GenBank,XP_750779,,,Af293,MAK5,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,probable RNA-helicase of the DEAD box family,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3114,PHI:2550,UniProt,Q4WES1,GenBank,XP_747944,,,Af293,NOB1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,"essential protein that functions in 20S proteasome maturation and 26S proteasome assembly, component of pre-40S ribosomal particle",,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3115,PHI:2551,UniProt,Q4WZG4,GenBank,XP_756039,,,Af293,NOC3,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,protein involved in biogenesis of the 60S ribosomal subunit,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3116,PHI:2552,UniProt,Q4WNM3,GenBank,XP_752199,,,Af293,NOP4,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,,,,Lethal pathogen phenotype,,,,nucleolar protein required for ribosome biogenesis,,,,lethal,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3117,PHI:2530,UniProt,Q4WKG5,GenBank,XP_750005,,,Af293,TUB1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised murine model for systemic infection using CD-1 male mice,,,whole body,tubulin alpha-1 chain,,,,loss of pathogenicity,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3118,PHI:2527,UniProt,Q4X0M4,GenBank,XP_755629,,,Af293,SEC31,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised murine model for systemic infection using CD-1 male mice,,,whole body,initiation of germ tubes,,,,loss of pathogenicity,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3119,PHI:2543,UniProt,Q4WLS1,GenBank,XP_751131,,,Af293,GCD6,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised murine model for systemic infection using CD-1 male mice,,,whole body,translation initiation factor eIF2B,,,,loss of pathogenicity,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3120,PHI:2513,UniProt,E9R5E2,GenBank,XP_750525,,,Af293,GFA1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised murine model for systemic infection using CD-1 male mice,,,whole body,glutamine-fructose-6-phosphate aminotransferase,,,,loss of pathogenicity,,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3121,PHI:2538,UniProt,Q4WXL8,GenBank,XP_754623,,,Af293,AUR1,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised murine model for systemic infection using CD-1 male mice,,,whole body,phosphatidyl-inositol:ceramide phosphoinositol transferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3122,PHI:2536,UniProt,Q4WU51,GenBank,XP_753913,,,Af293,MET2,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised murine model for systemic infection using CD-1 male mice,,,whole body,homoserine O-acetyl-transferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3123,PHI:2534,UniProt,Q4WNT5,GenBank,XP_752137,,,Af293,ERG11A,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised murine model for systemic infection using CD-1 male mice,,,whole body,14 alpha-demethylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3124,PHI:2535,UniProt,E9QY26,GenBank,XP_749134.1,,,Af293,ERG11B,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised murine model for systemic infection using CD-1 male mice,,,whole body,14 alpha-demethylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3125,PHI:2534,UniProt,Q4WNT5,GenBank,XP_752137,,,Af293,ERG11A,,,,,,PHI:2535,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised murine model for systemic infection using CD-1 male mice,,,whole body,14 alpha-demethylase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3126,PHI:2535,UniProt,E9QY26,GenBank,XP_749134.1,,,Af293,ERG11B,,,,,,PHI:2534,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised murine model for systemic infection using CD-1 male mice,,,whole body,14 alpha-demethylase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,AR,17352532,PubMed,10.1371/journal.ppat.0030024,,terry_roemer @merck.com,no comments,Wenqi Hu,2007,,,Batch017,2012-11-20,MC,,,,,,,,,,,,,
,,Record 3127,PHI:2597,UniProt,Q59PW0,,EAK92503,,,SC5314,Pir32,,,,,,,5476,Candida albicans,,RM1000,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,cell wall integrity,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,sodium lauryl sulfate; hydrogen peroxide; sodium chloride,sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1; sodium chloride: CAS:7647-14-5,,,,,gene deletion: full,,,RP,22391823,PubMed,10.1007/s11046-012-9533-z,,Roy.khalaf@lau.edu.lb,"Mutant was shown to be resistant to sodium dodecyl sulfate, hydrogen peroxide, sodium chloride.",Wael Bahnan,2012,,Bahnan-2012-Deletion of the Cand,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3128,PHI:3502,UniProt,Q59MD2,,EAK91630.1,,,SC5314,UME6,,,,,,,5476,Candida albicans,,DK318,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,transcriptional regulator,,,RFG1-TUP1 and NRG1- TUP1 filamentous growth regulatory pathways,reduced virulence,,,,,,,,defective,defective,no,,,,,,,gene deletion: full; gene complementation,,,RP,18216277,PubMed,10.1091/mbc.E07-11-1110,,kadosh@uthscsa.edu,no comments,Mohua Banerjee,2008,,"Banerjee-2008-UME6, a novel filame",Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3129,PHI:3503,UniProt,Q5AMH6,,EAL04005,,,SC5314,Cas5,,,,,,,5476,Candida albicans,,DAY185,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen,transcriptional regulator of genes involved in cell wall integrity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19463063,PubMed,10.1086/599363,,dkontoyi@mdanderson.org,no comments,Georgios Chamilos,2009,,Chamilos-2009-Candida albicans Cas,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3130,PHI:3503,UniProt,Q5AMH6,,EAL04005,,,SC5314,Cas5,,,,,,,5476,Candida albicans,,DAY185,candidiasis,flies,7227,Drosophila melanogaster (related: fruit fly),Toll mutant,,,kidney; spleen,transcriptional regulator of genes involved in cell wall integrity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19463063,PubMed,10.1086/599363,,dkontoyi@mdanderson.org,no comments,Georgios Chamilos,2009,,,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3131,PHI:3504,UniProt,P43079,,AAA64692.1,,,SC5314 / ATCC MYA-2876,cph1,,,,,,PHI:3505,5476,Candida albicans,237561,SC5314,candidiasis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo; adult,transcription factor controlling morphogenesis,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20308295,PubMed,10.1128/IAI.01293-09,,yjchuang@life.nthu.edu.tw,no comments,Chun-Cheih Chao,2010,,Chao-2010-Zebrafish as a model,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3132,PHI:3505,UniProt,Q59X67,,EAK95160.1,,,SC5314,efg1,,,,,,PHI:3504,5476,Candida albicans,237561,SC5314,candidiasis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo; adult,transcription factor controlling morphogenesis,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20308295,PubMed,10.1128/IAI.01293-09,,yjchuang@life.nthu.edu.tw,no comments,Chun-Cheih Chao,2010,,,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3133,PHI:3506,UniProt,Q5ABE2,,EAK99984.1,,,SC5314,hgc1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo; adult,hypha-specific G1 cyclin-related protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20308295,PubMed,10.1128/IAI.01293-09,,yjchuang@life.nthu.edu.tw,no comments,Chun-Cheih Chao,2010,,,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3134,PHI:3507,UniProt,Q59Y20,,EAK95409,,,SC5314,Dse1,,,,,,,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,cell wall protein involved in cell wall metabolism,,,,reduced virulence,,,,yes,,,,aberrant,,yes,7-diethylamino-4-methylcoumarin; sodium lauryl sulfate; hydrogen peroxide,7-diethylamino-4-methylcoumarin: CAS:91-44-1; sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1,,,,,gene deletion: full,,,RP,21760783,PubMed,10.1155/2011/504280,,roy.khalaf@lau.edu.lb,"The heterozygote mutant exhibited increased susceptibility to calcofluor white, a cell wall disrupting agent, and decreased oxidative stress tolerance",Jalil Y.Daher,2011,,Daher-2011-The Candida albicans,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3135,PHI:3508,UniProt,Q5A5U4,,EAK98052.1,,,SC5314,Rhd3/Pga29,chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,cell wall protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20533408,PubMed,10.1002/yea.1790,,mweig@gwdg.de,no comments,Albert D. de Boer,2010,,de Boer-2010-The Candida albicans,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3136,PHI:3509,UniProt,Q5A753,,EAK98608.1,,,SC5314,Opy2,,,,,,,5476,Candida albicans,,CAF2,candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,transmembrane protein,,,MAPK pathway,reduced virulence,,,,,,,,,,no,Congo red,Congo red: CAS:573-58-0,,,,,gene deletion: full; gene complementation,,,RP,23149115,PubMed,10.1016/j.fgb.2012.11.001,,realonso@farm.ucm.es,Mutant strains are more susceptible to congo red,Carmen Herrero de Dios,2012,,de Dios-2012-The transmembrane pr,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3137,PHI:2607,UniProt,Q4WXK4,,Afu3g09820,,,Af293,DvrA,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,putative C2H2 transcription factor,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,wild type,no,nikkomycin,nikkomycin: CAS:59456-70-1,,,,,gene disruption; gene complementation,,,RP,20675576,PubMed,10.1128/EC.00055-10,,sfiller@ucla.edu,"The mutant is resistant to nikkomycin Z, suggesting an altered cell wall composition",Daniele E. Ejzykowicz,2010,,Ejzykowicz-2010-Role of Aspergillus,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3138,PHI:2607,UniProt,Q4WXK4,,Afu3g09820,,,Af293,DvrA,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative C2H2 transcription factor,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,wild type,no,nikkomycin,nikkomycin: CAS:59456-70-1,,,,,gene disruption; gene complementation,,,RP,20675576,PubMed,10.1128/EC.00055-10,,sfiller@ucla.edu,"The mutant is resistant to nikkomycin Z, suggesting an altered cell wall composition",Daniele E. Ejzykowicz,2010,,,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3139,PHI:3511,UniProt,Q59PF9,,EAK92376.1,,,SC5314,HWP2,,,,,,,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative GPI-anchored cell wall protein,,,,reduced virulence,,,,yes,,,,reduced,,no,fluconazole; voriconazole; ketoconazole; itraconazole; amphotericin B; caspofungin,"fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CAS:137234-62-9; ketoconazole: CHEBI:47519, CAS:65277-42-1; itraconazole: CAS:84625-61-6; amphotericin B: CAS:1397-89-3; caspofungin: CAS:162808-62-0",,,,,gene deletion: full; gene complementation,,,RP,19616419,PubMed,10.1016/j.micres.2009.03.006,,roy.khalaf@lau.edu.lb,No significant discrepancy amongst the three strains was noted for all six drugs tested (p< 0.05),Peter Hayek,2010,,Hayek-2010-Characterization of,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3140,PHI:3512,UniProt,Q59ZX1,GenBank,XP_715022.1,,,SC5314 / ATCC MYA-2876,SET3,,,,,,,5476,Candida albicans,,SN152,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,histone deacetylase complex,,,cAMP/PKA signaling,reduced virulence,,,,,,,,aberrant,,no,adenine; glycerin,adenine: CAS:73-24-5; glycerin: CAS:56-81-5,,,,,gene deletion: full; gene complementation,,,RP,20485517,PubMed,10.1371/journal.ppat.1000889,,karl.kuchler@meduniw ien.ac.at,Adenine and glycerol were able to reverse the mutant effects of hyperfilamentation,Denes Hnisz,2010,,Hnisz-2010-The Set3_Hos2 histon,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3141,PHI:3497,UniProt,O42766,,AAB96910.2,,,SC5314,Bmh1p,,,,,,,5476,Candida albicans,,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen,multifunctional signal-modulating,,,several pathways implicated,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,19372164,PubMed,10.1099/mic.0.027532-0,,jsturt@lsuhsc.edu,no comments,Michelle N. Kelly,2009,,Kelly-2009-Bmh1p (14-3-3) media,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3142,PHI:3513,UniProt,Q5AAL9,,EAK99714.1,,,SC5314,IFF4,,,,,,,5476,Candida albicans,,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),Swiss white,,,kidney; spleen,GPI protein,,,,reduced virulence,,yes,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19347602,PubMed,10.1007/s11046-009-9201-0,,makempf@chu-angers.fr,no comments,Marie Kempf,2009,,Kempf-2009-Disruption of the GP,Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3143,PHI:3514,UniProt,P83774,,EAK93295.1,,,SC5314,Asc1,,,,,,,5476,Candida albicans,,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,component of the 40S ribosomal subunit,,,,loss of pathogenicity,,yes,,yes,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21221944,PubMed,10.1007/s12275-010-0422-1,,joonkim@korea.ac.kr,no comments,Se Woong Kim,2010,,"Kim-2010-Asc1p, a ribosomal p",Batch018,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3144,PHI:3515,UniProt,J9VI93,Broad,CNAG_00193.2,,,H99,Gat1,,,,,,,5207,Cryptococcus neoformans,235443,H99,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,zinc finger containing transcriptional regulators,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,20673806,PubMed,10.1016/j.fgb.2010.07.011,,mhv@cbiot.ufrgs.br,"The gat1 mutant exhibited impaired growth on all amino acids tested as sole nitrogen sources, with the exception of arginine and proline.",Lívia Kmetzsch,2011,,Kmetzsch-2011-The GATA-type transc-1886777682,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3145,PHI:3516,UniProt,Q5AA09,,EAK99572.1,,,SC5314,Pga26,,,,,,,5476,Candida albicans,,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,small cell wall protein,,,,reduced virulence,,,,,,,,increased; aberrant,,no,7-diethylamino-4-methylcoumarin; Congo red; zymolyase ; caspofungin; fluconazole; posaconazole; amphotericin B; hydrogen peroxide; calcium chloride anhydrous,"7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0; zymolyase: CAS:37340-57-1; caspofungin: CAS:162808-62-0; fluconazole: CHEBI:46081, CAS:86386-73-4; posaconazole: CAS:171228-49-2; amphotericin B: CAS:1397-89-3; hydrogen peroxide: CAS:7722-84-1; calcium chloride anhydrous: CAS:10043-52-4",,,,,gene disruption; gene complementation,,,RP,21439008,PubMed,10.1111/j.1567-1364.2011.00727.x,,eulogio.valentin@uv.es,"pga26 disruption mutants show increased susceptibilit y to antifungals (fluconazol, posaconazol or amphotericin B) that target the plasma membrane and have altered sensitivities to env ironmental (heat, osmotic and oxidative) and cell wall stresses",Leslie Laforet,2011,,Laforet-2011-Pga26 mediates filam-2423648594,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3146,PHI:2553,UniProt,Q5AG40,,EAL01811.1,,,SC5314,VPS4,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,pre-vacuolar protein sorting gene,,,pre-vacuolar secretory pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,18814053,PubMed,10.1007/s11046-008-9155-7,,SamALee@salud.unm.edu,no comments,Samuel A. Lee,2009,,Lee-2009-Candida albicans VPS-3195400530,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3147,PHI:2554,UniProt,Q59Z32,,EAK95753.1,,,SC5314,Rck2,,,,,,,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,Hog1p-MAP kinase-activated protein kinase,,,mitogen-activated protein (MAP) kinase,reduced virulence,,,,,,,,reduced,,no,Congo red; 7-diethylamino-4-methylcoumarin; zymolyase; sodium lauryl sulfate (SDS); caspofungin,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; zymolyase: CAS:37340-57-1; sodium lauryl sulfate: CAS:151-21-3; caspofungin: CAS:162808-62-0,,,,,gene deletion: full; gene complementation,,,RP,20402792,PubMed,10.1111/j.1567-1364.2010.00626.x,,linghuojiang2@yahoo.com.cn,"Deletion of CaRCK2 renders C. albicans cells sensitive to, and CaRck2p translocates from the cytosol to the nucleus in response to, cell wall stresses caused by Congo red, Calcoflor White, elevated heat and zymolyase.",Xichuan Li,2010,,Li-2010-The MAP kinase-activ,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3148,PHI:2555,UniProt,Q59Z29,GenBank,XP_714862.1,,,SC5314,CaAFT2,,,,,,,5476,Candida albicans,,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,transcription factor in ferric reductase activity,,,iron-regulated pathway(s),reduced virulence,,yes,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20595261,PubMed,10.1099/mic.0.037978-0,,nklimingchun@yahoo.com.cn,no comments,Yong Liang,2010,,Liang-2010-Role of Candida albi-0209056338,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3149,PHI:2556,UniProt,Q5AKA8,,EAL03042.1,,,SC5314,GLN3,,,,,,,5476,Candida albicans,,CAI4,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,global regulator of nitrogen metabolism and virulence,,,TOR kinase signaling pathway,reduced virulence,,,,,,,,reduced,,no,sirolimus,CAS:53123-88-9,,,,,gene deletion: full; gene complementation,,,RP,17950010,PubMed,10.1016/j.fgb.2007.08.006,,fonziw@georgetown.edu,gln3 mutants were nonfilamentous when the nitrogen source was either ammonium or urea,Wei-Li Liao,2008,,Liao-2008-GLN3 encodes a globa-0477491794,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3150,PHI:2557,UniProt,Q5AHG6,,EAL02133.1,,,SC5314,CaSch9p,,,,,,,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,protein kinase,,,TOR kinase signaling pathway,reduced virulence,,,,,,,,reduced; aberrant,,no,sirolimus; caffeine; lithium chloride; sodium chloride; potassium chloride; sodium lauryl sulfate,sirolimus: CAS:53123-88-9; caffeine: CAS:95789-13-2; lithium chloride: CAS:7447-41-8; sodium chloride: CAS:7647-14-5; potassium chloride: CAS:7447-40-7; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full; gene complementation,,,RP,20345900,PubMed,10.1111/j.1567-1364.2010.00617.x,,linghuojiang@yahoo.com.cn,"Deletion of CaSCH9 renders C. albicans cells sensitive to rapamycin,caffeine, sodium dodecyl sulfate and cations",Wei Liu,2010,,Liu-2010-The protein kinase C-0997585490,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3151,PHI:2558,UniProt,Q59P00,,EAK92179.1,,,SC5314,DUR31,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,sodium/substrate symporter family (SSSF),,,extracellular alkalinization hyphal auto-induction pathway,reduced virulence,,,,,,,,wild type; aberrant,,no,Congo red; silver nitrate,Congo red: CAS:573-58-0; silver nitrate: CAS:7761-88-8,,,,,gene deletion: full; gene complementation,,,RP,22438810,PubMed,10.1371/journal.ppat.1002592,,Bernhard.Hube@hki-jena.de,Deletion mutants more sensitive to congo red and silver nitrate than wild type strains,Francois L. Mayer,2012,,Mayer-2012-The novel Candida al-1517679186,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3152,PHI:2559,UniProt,Q6FPV9,GenBank,XP447735,,,CBS138,Slt2,,,,,,,5478,Candida glabrata,284593,CBS 138,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,maintaining fungal cell wall integrity,,,Slt2 mitogen-activated protein kinase pathway,reduced virulence,,,,,,,,defective,,no,Congo red; 7-diethylamino-4-methylcoumarin; micafungin,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; micafungin: CAS:235114-32-6,,,,,gene deletion: full; gene complementation,,,RP,20214686,PubMed,10.1111/j.1567-1364.2010.00611.x,,taiga-m@nagasaki-u.ac.jp,"The Dslt2 strain showed decreased tolerance to Congo red (inhibitor of chitin and b -glucan fiber formation), calcofluor white (inhibitor of chitin polymer assembly), and micafungin (inhibitor of b1,3-g lucan synthesis) compared with the wild-type control.",Taiga Miyazaki,2010,,Miyazaki-2010-Role of the Slt2 mit-2306208338,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3153,PHI:2559,UniProt,Q6FPV9,GenBank,XP447735,,,CBS138,Slt2,,,,,,,5478,Candida glabrata,284593,CBS 138,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,maintaining fungal cell wall integrity,,,Slt2 mitogen-activated protein kinase pathway,increased virulence (hypervirulence),,,,,,,,increased,,no,Congo red; 7-diethylamino-4-methylcoumarin; micafungin,Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; micafungin: CAS:235114-32-6,,,,,altered gene expression / gene regulation: overexpression,,,RP,20214686,PubMed,10.1111/j.1567-1364.2010.00611.x,,taiga-m@nagasaki-u.ac.jp,"The overexpressed slt2 strain showed increased tolerance to Congo red (inhibitor of chitin and b -glucan fiber formation), calcofluor white (inhibitor of chitin polymer assembly), and micafungin (inhibitor of b1,3-g lucan synthesis) compared with the wild-type control.",Taiga Miyazaki,2010,,,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3154,PHI:2560,UniProt,Q6FLU4,,CAG61770.1,,,CBS138,CNB1,,,,,,,5478,Candida glabrata,284593,CBS 138,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; kidney,serine-threonine-specific protein phosphatase,,,calcineurin pathway,reduced virulence,,,,,,,,wild type,,no,fluconazole; Congo red; 7-diethylamino-4-methylcoumarin; micafungin,"fluconazole: CHEBI:46081, CAS:86386-73-4; Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; micafungin: CAS:235114-32-6",,,,,gene deletion: full; gene complementation,,,RP,20100876,PubMed,10.1128/AAC.01364-09,,taiga-m@nagasaki-u.ac.jp,"The drug was fungicidal for the deleted cnb1 strain. In contrast, the deletion of CRZ1 did not affect the antifungal activity of fluconazole. These results suggest that calcineurin is involved in azole tolerance via a Crz1-independent pathway in C. glabrata/ Decreased micafungin tolerance was observed in the cnb1 and crz1 strains/ cnb1 strain showed decreased tolerance to both Congo red and calcofluor white, the crz1 strain exhibited only moder-ately decreased tolerance to Congo red and was unaffected by calcofluor white exposure.",Taiga Miyazaki,2010,,Miyazaki-2010-Roles of calcineurin-2574643794,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3155,PHI:2561,UniProt,Q6FJF0,,CAG62620.1,,,CBS138,Crz1,,,,,,,5478,Candida glabrata,284593,CBS 138,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; kidney,transcription factor,,,calcineurin pathway,reduced virulence,,,,,,,,wild type,,no,fluconazole; Congo red; 7-diethylamino-4-methylcoumarin; micafungin,"fluconazole: CHEBI:46081, CAS:86386-73-4; Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; micafungin: CAS:235114-32-6",,,,,gene deletion: full; gene complementation,,,RP,20100876,PubMed,10.1128/AAC.01364-09,,taiga-m@nagasaki-u.ac.jp,"The drug was fungicidal for the deleted cnb1 strain. In contrast, the deletion of CRZ1 did not affect the antifungal activity of fluconazole. These results suggest that calcineurin is involved in azole tolerance via a Crz1-independent pathway in C. glabrata/ Decreased micafungin tolerance was observed in the cnb1 and crz1 strains/ cnb1 strain showed decreased tolerance to both Congo red and calcofluor white, the crz1 strain exhibited only moder-ately decreased tolerance to Congo red and was unaffected by calcofluor white exposure.",Taiga Miyazaki,2010,,,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3156,PHI:2562,UniProt,Q59M50,,EAK91556.1,,,SC5314,Cwt1,,,,,,,5476,Candida albicans,,,candidiasis,rodents,10090,Mus musculus (related: house mouse),Swiss white,,,kidney,transcription factor involved in cell wall architecture,,,mitogen-activated protein (MAP) kinase pathway,reduced virulence,,,,,,,,defective,wild type,no,Congo red; 7-diethylamino-4-methylcoumarin; sodium lauryl sulfate; ketoconazole,"Congo red: CAS:573-58-0; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; sodium lauryl sulfate: CAS:151-21-3; ketoconazole: CHEBI:47519, CAS:65277-42-1",,,,,gene deletion: full; gene complementation,,,RP,19908200,PubMed,10.1002/yea.1733,,Eulogio.Valentin@uv.es,"Homozygous cwt1 mutants showed increased sensitivity to calcofluor white and Congo red, and a minor sensitivity to sodium dodecyl sulphate / the homozygous cwt1 null mutant was as sen-sitive to ketoconazole as the wild-type strain, while, surprisingly, the CWT1 /cwt1 heterozygous mutant was more resistant.",Inmaculada Moreno,2010,,Moreno-2010-Dosage-dependent rol-3094737490,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3157,PHI:2563,UniProt,Q5AH74,,EAL01966.1,,,SC5314,DPP3,,,,,,,5476,Candida albicans,,SN152,candidiasis,rodents,10090,Mus musculus (related: house mouse),CF1,,,kidney,phosphatase which converts farnesyl pyrophosphate to farnesol,,,,reduced virulence,,,,,,,,wild type,,no,farnesol,CAS:4602-84-0,,,,,gene deletion: full; gene complementation,,,RP,17283095,PubMed,10.1128/IAI.01182-06,,knickerson1@unl.edu,"Reduced endogenous farnesol decreased virulence, while providing exogenous farnesol increased virulence",Dhammika H. M,2007,,Navarathna-2007-Effect of farnesol o-1937109842,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3158,PHI:2564,UniProt,G8BCQ2,,CCE43047.1,,,CDC317,OLE1,,,,,,,5480,Candida parapsilosis,,GA1,candidemia,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen; liver; kidney,essential for unsaturated fatty acid (UFA) production,,,OLE1 pathway,reduced virulence,,yes,,,,,,reduced,,no,sodium chloride; potassium chloride; sodium lauryl sulfate; hydrogen peroxide; unsaturated fatty acids,sodium chloride: CAS:7647-14-5; potassium chloride: CAS:7447-40-7; sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1,,,,,gene deletion: full; gene complementation,,,RP,20974817,PubMed,10.1128/IAI.00753-10,,josh.nosanchuk@einstein.yu.edu,"Ole1 is essential for cell survival under stress conditions, especially at physiological temperatures",Long Nam Nguyen,2011,,Nguyen-2011-The stearoyl-coenzym-2205545298,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3159,PHI:2565,UniProt,Q5AQ33,GenBank,XP_723271.1,,,SC5314,HSF1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,heat shock transcription factor,,,,reduced virulence,,,,,,,,,,yes,,,,,,,gene mutation: characterised,,,RP,20817114,PubMed,10.1016/j.fgb.2010.08.010,,al.brown@abdn.ac.uk,HSF1 is essential for viability in C. albicans hence only a mutation in the CE2 region used,Susan Nicholls,2011,,Nicholls-2011-Activation of the he-3245732690,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3160,PHI:2566,UniProt,Q6FTT1,,CAG59287.1,,,CBS138,Skn7p,,,,,,,5478,Candida glabrata,284593,CBS 138,candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; kidney,transcriptional factor involved in oxidative stress response,,,,reduced virulence,,,,,,,,wild type,,no,hydrogen peroxide; tert-butyl hydroperoxide (t-BOOH),hydrogen peroxide: CAS:7722-84-1; tert-butyl hydroperoxide: CAS:75-91-2,,,,,gene deletion: full; gene complementation,,,RP,19693686,PubMed,10.1007/s11046-009-9233-5,,koizumik@nagasaki-u.ac.jp,Skn7 deletant showed increased susceptibility to hydrogen peroxide and tertbutyl hydroperoxide.,Tomomi Saijo,2010,,Saijo-2010-Skn7p is involved in,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3161,PHI:2567,UniProt,Q5ACU9,,EAL00685.1,,,SC5314,CaNdt80p,,,,,,,5476,Candida albicans,,BWP17,candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,transcription factor,,,,loss of pathogenicity,,,,,,,,reduced; defective,,no,,,,,,,gene deletion: full; gene complementation,,,RP,20097739,PubMed,10.1128/EC.00325-09,,andre.nantel@nrc-cnrc.gc.ca,no comments,Adnane Sellam,2010,,Sellam-2010-Role of transcriptio-4034261842,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3162,PHI:2568,UniProt,Q5AMP9,,EAL03932.1,,,SC5314,CAP2,,,,,,,5476,Candida albicans,,SN152,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; brain,regulation of iron homeostasis,,,iron-acquisition pathways,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,21592964,PubMed,10.1074/jbc.M111.233569,,nat0200@mail.jnu.ac.in,CAP2/HAP43 gene was required for growth of C. albicans under iron deprivation conditions,Rana Pratap Singh,2011,,Singh-2011-Cap2-HAP complex is-0779482194,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3163,PHI:2569,UniProt,Q5AK51,,EAL03099.1,,,SC5314,SFL2,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,gastrointestinal tract,temperature induced transcriptional regulator,,,,reduced virulence,,yes,yes,yes,,,,defective,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21205158,PubMed,10.1111/j.1567-1364.2010.00710.x,,jychen@sibs.ac.cn,no comments,Wenji Song,2011,,Song-2011-Candida albicans Sfl-1836446802,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3164,PHI:2570,UniProt,Q6FM61,,CAGL0K10736g,,,CBS138,CYB2,,,,,,,5478,Candida glabrata,284593,CBS 138,candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6JJcl,,,cecum,lactate dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21931845,PubMed,10.1371/journal.pone.0024759,,chibana@faculty.chib a-u.jp,"The Dcyb2 mutant could not grow on lactate medium in which lactate is the sole carbon source in the absence of glucose, indicating that Cyb2p plays a role in lactate assimilation",Keigo Ueno,2011,,Ueno-2011-Intestinal resident-2088105042,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3165,PHI:2571,UniProt,Q59QS7,GenBank,XP_712029,,,SC5314,ZCF13,,,,,,,5476,Candida albicans,,,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,potential fungal transcription factor,,,,reduced virulence,,,,,,,,aberrant; defective,,no,,,,,,,gene disruption; gene complementation,,,AR,22073120,PubMed,10.1371/journal.pone.0026962,,alix.coste@chuv.ch,Increased susceptibility to heat,Patrick Vandeputte,2011,,Vandeputte-2011-In vivo systematic a,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3166,PHI:2572,UniProt,Q5A4N7,GenBank,XP_716655,,,SC5314,ZCF18,,,,,,,5476,Candida albicans,,,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,potential zinc finger upstream protein 1,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,AR,22073120,PubMed,10.1371/journal.pone.0026962,,alix.coste@chuv.ch,Mutant for orf19.3405 showed a growth deficiency in all conditions tested but displayed an increased production of true hyphae in liquid YEPD supplemented with 10% FCS.,Patrick Vandeputte,2011,,,Batch019,2012-12-01,MC,,,,,,,,,,,,,
,,Record 3167,PHI:2573,UniProt,H2DQH1,,AEY79687.1,,,,CUB,,,,,,,5693,Trypanosoma cruzi,353153,CL Brener,Chagas disease,,,,Lethal pathogen phenotype,,,,calmodulin-ubiquitin associated (CUB) gene,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,8813691,PubMed,10.1016/S0166-6851(96)02627-8,,,"Individually either CUB gene is dispensable, both can be deleted only when an additional copy is expressed from an alternative locus. It is essential for the viability of the pathogen",John Swindle,1996,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3168,PHI:2574,UniProt,D3JLB9,,ADB79673.1,,,OK Dog,Tc52,,,,,,,5693,Trypanosoma cruzi,,Y,Chagas disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,thiol-disulphide redox reactions,,,,unaffected pathogenicity,,,,,,,,wild type,,yes,nifurtimox; benznidazole; potassium antimonial tartrate (SbIII),nifurtimox: CAS:23256-30-6; benznidazole: CAS:22994-85-0; antimony potassium tartrate: CAS:28300-74-5,,,,,gene deletion: full,,,RP,10383767,PubMed,10.1046/j.1365-2958.1999.01440.x,,ali.ouaissi@montp.inserm.fr,"The drugs had similar effects on wild-type and mutant parasites, being equally sensitive",Abdelmounaaïm Allaoui,1999,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3169,PHI:2575,UniProt,Q4D3W2,,EAN87213.1,,,CL Brener,DHOD,,,,,,,5693,Trypanosoma cruzi,,Tulahuen,Chagas disease,,,,Lethal pathogen phenotype,,,,fumarate reductase activity,,,pyrimidine biosynthetic pathway,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,15696374,PubMed,10.1007/s00239-004-0078-8,,tnara@med.juntendo.ac.jp,"DHOD-knockout T. cruzi did not express the enzyme protein and could not survive even in the presence of pyrimidine nu-cleosides, substrates for the potentially active salvage pathway, suggesting a vital role of fumarate reduc-tase activity in the regulation of cellular redox balance.",Takeshi Annoura,2005,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3170,PHI:2576,UniProt,H2DQH1,,AEY79687.1,,,,CUB,,,,,,,5693,Trypanosoma cruzi,,Tulahuen,Chagas disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,calmodulin-ubiquitin associated (CUB) gene,,,,reduced virulence,,,,,,,,reduced,,yes,,,,,,,gene deletion: full; gene complementation,,,RP,17624327,PubMed,10.1016/j.exppara.2007.05.005,,basombri@unsa.edu.ar,"After targeted deletion, a clone (TulCub8) was derived where one of the two alleles was disrupted. This clone displayed a sharp and stable loss of virulence for mice.",Alejandra B. Barrio,2007,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3171,PHI:2576,UniProt,H2DQH1,,AEY79687.1,,,,CUB,,,,,,,5693,Trypanosoma cruzi,,Tulahuen,Chagas disease,rodents,10090,Mus musculus (related: house mouse),SWR,,,,calmodulin-ubiquitin associated (CUB) gene,,,,reduced virulence,,,,,,,,reduced,,yes,,,,,,,gene deletion: full; gene complementation,,,RP,17624327,PubMed,10.1016/j.exppara.2007.05.005,,basombri@unsa.edu.ar,"After targeted deletion, a clone (TulCub8) was derived where one of the two alleles was disrupted. This clone displayed a sharp and stable loss of virulence for mice.",Alejandra B. Barrio,2007,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3172,PHI:2577,,no data found,GenBank,ES225905,,,Tobacco-adapted lineage (red),Mp10,,,,,,,13164,Myzus persicae,,RRes (genotype O),,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,candidate effector genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,21124944,PubMed,10.1371/journal.pgen.1001216,,saskia.hogenhout@bbsrc.ac.uk,A. tumefaciens strain GV3101 was used in molecular cloning and agroinfiltration experiments,Jorunn I. B. Bos,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3173,PHI:2578,,no data found,GenBank,EE264844,,,Tobacco-adapted lineage (red),Mp42,,,,,,,13164,Myzus persicae,,RRes (genotype O),,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,candidate effector genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,21124944,PubMed,10.1371/journal.pgen.1001216,,saskia.hogenhout@bbsrc.ac.uk,A. tumefaciens strain GV3101 was used in molecular cloning and agroinfiltration experiments,Jorunn I. B. Bos,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3174,PHI:2579,,no data found,GenBank,EC389531,,,Tobacco-adapted lineage (red),MpCOO2,,,,,,,13164,Myzus persicae,,RRes (genotype O),,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,candidate effector genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,21124944,PubMed,10.1371/journal.pgen.1001216,,saskia.hogenhout@bbsrc.ac.uk,A. tumefaciens strain GV3101 was used in molecular cloning and agroinfiltration experiments,Jorunn I. B. Bos,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3175,PHI:2580,UniProt,Q94795,,AAC80228,,,,Oligopeptidase B,,,,,,,5693,Trypanosoma cruzi,,Y,Chagas disease,rodents,10090,Mus musculus (related: house mouse),C3H,,,,"oligopeptidase B functions as a processing enzyme, generating an active Ca2 agonist from a cytosolic precursor molecule",,,calcium signaling,reduced virulence,,,yes,yes,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,9724634,PubMed,10.1093/emboj/17.17.4975,,norma_andrews@qm.yale.edu,no comments,Elisabet V.Caler,1998,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3176,PHI:2581,UniProt,Q4PH32,,FN395064,,,,Rim9,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,leaf,pH response / involved in the formation of one of the signaling complexes located at the plasma membrane together with PalF/Rim21 and PalH/Rim8 proteins,,,Rim or Pal pathway,unaffected pathogenicity,no,,,,,wild type,,wild type,wild type,no,lithium chloride; sodium chloride; sodium lauryl sulfate; hydrogen peroxide; Congo red,lithium chloride: CAS:7447-41-8; sodium chloride: CAS:7647-14-5; sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1; Congo red: CAS:573-58-0,,,,,gene deletion: full,,,RP,20153837,PubMed,10.1016/j.fgb.2010.02.004,,jruiz@ira.cinvestav.mx,rim9 is unaffected by any of the tested stresses,Cervantes-Chávez José Antonio,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3177,PHI:2582,UniProt,D2EAX7,EMBL,FN395061,,,,Rim20,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,leaf,pH response / involvement in endosomal targeting,,,Rim or Pal pathway,unaffected pathogenicity,no,,,,,wild type,,wild type,wild type,no,lithium chloride; sodium chloride; sodium lauryl sulfate; hydrogen peroxide; Congo red,lithium chloride: CAS:7447-41-8; sodium chloride: CAS:7647-14-5; sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1; Congo red: CAS:573-58-0,,,,,gene deletion: full,,,RP,20153837,PubMed,10.1016/j.fgb.2010.02.004,,jruiz@ira.cinvestav.mx,pH dependant sensitivity to stress,Cervantes-Chávez José Antonio,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3178,PHI:2583,UniProt,Q4PCT8,,FN395062,,,,Rim13,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,leaf,pH response / encodes a putative calcium-activated cys-teine protease (calpain-like),,,Rim or Pal pathway,unaffected pathogenicity,no,,,,,wild type,,wild type,wild type,no,lithium chloride; sodium chloride; sodium lauryl sulfate; hydrogen peroxide; Congo red,lithium chloride: CAS:7447-41-8; sodium chloride: CAS:7647-14-5; sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1; Congo red: CAS:573-58-0,,,,,gene disruption,,,RP,20153837,PubMed,10.1016/j.fgb.2010.02.004,,jruiz@ira.cinvestav.mx,pH dependant sensitivity to stress,Cervantes-Chávez José Antonio,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3179,PHI:2584,UniProt,Q4P671,,FN395063,,,,Rim23,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,leaf,pH response / putatively involved in endocytic trafficking,,,Rim or Pal pathway,unaffected pathogenicity,no,,,,,wild type,,wild type,wild type,no,lithium chloride; sodium chloride; sodium lauryl sulfate; hydrogen peroxide; Congo red,lithium chloride: CAS:7447-41-8; sodium chloride: CAS:7647-14-5; sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1; Congo red: CAS:573-58-0,,,,,gene disruption,,,RP,20153837,PubMed,10.1016/j.fgb.2010.02.004,,jruiz@ira.cinvestav.mx,pH dependant sensitivity to stress,Cervantes-Chávez José Antonio,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3180,PHI:2585,UniProt,I3QHH8,,JQ716919,,,,SKN7,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot (Citrus),eudicots,229630,Citrus x tangelo (related: tangelo),,,,leaf,stress-responsive transcription regulator,,,SKN7-mediated signaling pathway with HSK1 and HOG1,reduced virulence,,,,,,reduced; aberrant,,reduced,wild type,no,tert-butyl hydroperoxide (t-BHP); hydrogen peroxide; cumene hydroperoxide; glucose; sucrose; sorbitol; mannitol; sodium lauryl sulfate,tert-butyl hydroperoxide: CAS:75-91-2; hydrogen peroxide: CAS:7722-84-1; cumene hydroperoxide: CAS:80-15-9; glucose: CAS:50-99-7; sucrose: CAS:57-50-1; sorbitol: CAS:50-70-4; mannitol: CAS:69-65-8; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full; gene complementation,,,RP,22902811,PubMed,10.1016/j.fgb.2012.07.006,,krchung@ufl.edu,"Mutational inactivation of the SKN7 gene resulted in fungal strains (D52 and D61) that display hypersensitivity to tert-butyl-hydroxyperoxide (t-BHP), H2O2, cumyl H2O2, glucose, sucrose, sorbitol, mannitol, and SDS. Mutants more resistant to the dicarboximide and phenylpyrrole fungicides.",Li-Hung Chen,2012,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3181,PHI:2586,UniProt,Q4P380,,EAK86491,,,521,Pmt4,chromosome 19,,,,,,5270,Ustilago maydis,559306,SG200; FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling; leaf,O-mannosyltransferase,,,MAP kinase,reduced virulence,,yes,yes,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22416226,PubMed,10.1371/journal.ppat.1002563,,joibecor@upo.es,no comments,Alfonso Fernandez-Alvarez,2012,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3182,PHI:2587,UniProt,F8R4Y0,,AB725683,,,,ACRTS2,,,,,,,5599,Alternaria alternata,,HC1,leaf spot,eudicots,64884,Citrus jambhiri (related: rough lemon),,,,leaf,putative polyketide synthase,,,,reduced virulence,,,,,necrotic lesions,wild type,,wild type,wild type,no,,,,,,,gene disruption,,,RP,22835272,PubMed,10.1094/MPMI-06-12-0155-R,,kazuya@ag.kagawa-u.ac.jp,no comments,Y. Izumi,2012,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3183,PHI:2587,UniProt,F8R4Y0,,AB725683,,,,ACRTS2,,,,,,,5599,Alternaria alternata,,HC1,leaf spot,eudicots,64884,Citrus jambhiri (related: rough lemon),,,,leaf,putative polyketide synthase,,,,reduced virulence,,,,,necrotic lesions,wild type,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,22835272,PubMed,10.1094/MPMI-06-12-0155-R,,kazuya@ag.kagawa-u.ac.jp,no comments,Y. Izumi,2012,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3184,PHI:2588,UniProt,B2CQJ9,,ACB59235,,,G217B,VEA1,,,,,,,5037,Histoplasma capsulatum,,UC26,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,sexual development and toxin production,,,,reduced virulence,no,,,,,wild type,reduced,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,22841690,PubMed,10.1016/j.fgb.2012.07.001,,alan.smulian@uc.edu,Growth reduced at acidic pH,Meggan C. Laskowski-Peak,2012,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3185,PHI:2589,UniProt,Q7YZA8,,CAE17296,,,CL Brener,TcGALE,,unable to make TcGALE-/- null mutant (gene is essential),,,,,5693,Trypanosoma cruzi,353153,CL Brener,Chagas disease,,,,Lethal pathogen phenotype,,,,UDP-glucose 4-epimerase is encoded by the TcGALE gene,,,,lethal,,,,,,,,wild type,,yes,,,,,,,gene deletion: full,,,RP,16569451,PubMed,10.1016/j.molbiopara.2006.02.011,,m.a.j.ferguson@dundee.ac.uk,TcGALE+/- single-allele knockout clones were generated these heterozygous mutant lines had aberrant in vitro growth,James I. MacRae,2006,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3186,PHI:2590,UniProt,H9C592,,JQ234921,,,,CMLE,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,wilt (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker ss590,,,root,"3-carboxy-cis,cis-muconate lactonizing enzyme",,,b -ketoadipate pathway,loss of pathogenicity,,no,no,yes,,,,wild type,wild type,no,"ferulic acid; p-coumaric acid; vanillic acid; 4-hydroxybenzoic acid; p-hydroxybenzaldehyde; 2-propenoic acid, 3-phenyl-, (2E)-; catechol; lignin","ferulic acid: CAS:1135-24-6; p-coumaric acid: CAS:7400-08-0; vanillic acid: CAS:121-34-6; 4-hydroxybenzoic acid: CAS:99-96-7; p-hydroxybenzaldehyde: CAS:123-08-0; 2-propenoic   acid,   3-phenyl-,  (2E)-: CAS:140-10-3; catechol: CAS:120-80-9; lignin: CAS:9005-53-2",,,,,gene deletion: full; gene complementation,,,RP,22827542,PubMed,10.1111/J.1364-3703.2012.00818.X,,c.b.michielse@uni-muenster.de,Aromatic compunds affect the growth and conidiation of the deletion mutants,CAROLINE B. MICHIELSE,2012,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3187,PHI:2591,,no data found,GenBank,EU214531,,,VW4,cg-1,,,,,,,6303,Meloidogyne javanica,,VW4,,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,18393617,PubMed,10.1094/MPMI-21-5-0576,,vmwilliamson@ucdavis.edu,no comments,Cynthia A. Gleason,2008,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3188,PHI:2592,UniProt,Q4D8D9,GenBank,XP_810645,,,927/4,TcNTR,chromosome 7,,,,,,5693,Trypanosoma cruzi,,,African trypanosomiasis,,,,Lethal pathogen phenotype,,,,,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,18367671,PubMed,10.1073/pnas.0711014105,,s.r.wilkinson@qmul.ac.uk,Increased nitroheterocyclic drug resistance,Shane R. Wilkinson,2008,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3189,PHI:2593,UniProt,Q9NG46,GenBank,AF263616_1,,,CL Brenner,LYT1,,mutant LYT1 null derivative L16 clone,,,,,5693,Trypanosoma cruzi,353153,CL Brener,Chagas disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; skeletal muscle; spleen; urinary bladder,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,17938222,PubMed,10.1128/IAI.00400-07,,basombri@unsa.edu.ar,no comments,M. Paola Zago,2008,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3190,PHI:2593,UniProt,Q9NG46,GenBank,AF263616_1,,,CL Brenner,LYT1,,mutant LYT1 null derivative L16 clone,,,,,5693,Trypanosoma cruzi,353153,CL Brener,Chagas disease,rodents,10090,Mus musculus (related: house mouse),Swiss white,,,heart; skeletal muscle; spleen; urinary bladder,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,17938222,PubMed,10.1128/IAI.00400-07,,basombri@unsa.edu.ar,no comments,M. Paola Zago,2008,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3191,PHI:2594,UniProt,H2DQH1,,AEY79687.1,,,,CUB,,,,,,,5693,Trypanosoma cruzi,353153,CL Brener,Chagas disease,,,,Lethal pathogen phenotype,,,,calmodulin-ubiquitin associated (CUB) gene,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,8813691,PubMed,10.1016/S0166-6851(96)02627-8,,,"Individually either CUB gene is dispensable, both can be deleted only when an additional copy is expressed from an alternative locus. It is essential for the viability of the pathogen",John Swindle,1996,1 gene,1-s2.0-S0166685196026278-main,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3192,PHI:2595,UniProt,D3JLB9,,ADB79673.1,,,OK Dog,Tc52,,,,,,,5693,Trypanosoma cruzi,,Y,Chagas disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,thiol-disulphide redox reactions,,,,unaffected pathogenicity,,,,,,,,wild type,,yes,nifurtimox; benznidazole; potassium antimonial tartrate (SbIII),nifurtimox: CAS:23256-30-6; benznidazole: CAS:22994-85-0; antimony potassium tartrate: CAS:28300-74-5,,,,,gene deletion: full,,,RP,10383767,PubMed,10.1046/j.1365-2958.1999.01440.x,,ali.ouaissi@montp.inserm.fr,"The drugs had similar effects on wild-type and mutant parasites, being equally sensitive",Abdelmounaaïm Allaoui,1999,1 gene,Allaoui-1999-Intracellular growth,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3193,PHI:2596,UniProt,Q4D3W2,,EAN87213.1,,,CL Brener,DHOD,,,,,,,5693,Trypanosoma cruzi,,Tulahuen,Chagas disease,,,,Lethal pathogen phenotype,,,,fumarate reductase activity,,,pyrimidine biosynthetic pathway,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,15696374,PubMed,10.1007/s00239-004-0078-8,,tnara@med.juntendo.ac.jp,"DHOD-knockout T. cruzi did not express the enzyme protein and could not survive even in the presence of pyrimidine nu-cleosides, substrates for the potentially active salvage pathway, suggesting a vital role of fumarate reduc-tase activity in the regulation of cellular redox balance.",Takeshi Annoura,2005,1 gene,Annoura-2005-The origin of dihydr,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3194,PHI:3501,UniProt,H2DQH1,,AEY79687.1,,,,CUB,,,,,,,5693,Trypanosoma cruzi,,Tulahuen,Chagas disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,calmodulin-ubiquitin associated (CUB) gene,,,,reduced virulence,,,,,,,,reduced,,yes,,,,,,,gene deletion: full; gene complementation,,,RP,17624327,PubMed,10.1016/j.exppara.2007.05.005,,basombri@unsa.edu.ar,"After targeted deletion, a clone (TulCub8) was derived where one of the two alleles was disrupted. This clone displayed a sharp and stable loss of virulence for mice.",Alejandra B. Barrio,2007,1 gene,Barrio-2007-Trypanosoma cruzi_ a,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3195,PHI:3501,UniProt,H2DQH1,,AEY79687.1,,,,CUB,,,,,,,5693,Trypanosoma cruzi,,Tulahuen,Chagas disease,rodents,10090,Mus musculus (related: house mouse),SWR,,,,calmodulin-ubiquitin associated (CUB) gene,,,,reduced virulence,,,,,,,,reduced,,yes,,,,,,,gene deletion: full; gene complementation,,,RP,17624327,PubMed,10.1016/j.exppara.2007.05.005,,basombri@unsa.edu.ar,"After targeted deletion, a clone (TulCub8) was derived where one of the two alleles was disrupted. This clone displayed a sharp and stable loss of virulence for mice.",Alejandra B. Barrio,2007,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3196,PHI:2598,,no data found,GenBank,ES225905,,,Tobacco-adapted lineage (red),Mp10,,,,,,,13164,Myzus persicae,,RRes (genotype O),,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,candidate effector genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,21124944,PubMed,10.1371/journal.pgen.1001216,,saskia.hogenhout@bbsrc.ac.uk,A. tumefaciens strain GV3101 was used in molecular cloning and agroinfiltration experiments,Jorunn I. B. Bos,2010,Multi gene,Bos-2010-A functional genomic,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3197,PHI:2599,,no data found,GenBank,EE264844,,,Tobacco-adapted lineage (red),Mp42,,,,,,,13164,Myzus persicae,,RRes (genotype O),,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,candidate effector genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,21124944,PubMed,10.1371/journal.pgen.1001216,,saskia.hogenhout@bbsrc.ac.uk,A. tumefaciens strain GV3101 was used in molecular cloning and agroinfiltration experiments,Jorunn I. B. Bos,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3198,PHI:2600,,no data found,GenBank,EC389531,,,Tobacco-adapted lineage (red),MpCOO2,,,,,,,13164,Myzus persicae,,RRes (genotype O),,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,candidate effector genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,21124944,PubMed,10.1371/journal.pgen.1001216,,saskia.hogenhout@bbsrc.ac.uk,A. tumefaciens strain GV3101 was used in molecular cloning and agroinfiltration experiments,Jorunn I. B. Bos,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3199,PHI:2601,UniProt,Q94795,,AAC80228,,,,Oligopeptidase B,,,,,,,5693,Trypanosoma cruzi,,Y,Chagas disease,rodents,10090,Mus musculus (related: house mouse),C3H,,,,"oligopeptidase B functions as a processing enzyme, generating an active Ca2 agonist from a cytosolic precursor molecule",,,calcium signaling,reduced virulence,,,yes,yes,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,9724634,PubMed,10.1093/emboj/17.17.4975,,norma_andrews@qm.yale.edu,no comments,Elisabet V.Caler,1998,1 gene,Caler-1998-Oligopeptidase B-dep,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3200,PHI:2602,UniProt,D2EAY0,,FN395064,,,,Rim9,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,leaf,pH response / involved in the formation of one of the signaling complexes located at the plasma membrane together with PalF/Rim21 and PalH/Rim8 proteins,,,Rim or Pal pathway,unaffected pathogenicity,no,,,,,wild type,,wild type,wild type,no,lithium chloride; sodium chloride; sodium lauryl sulfate; hydrogen peroxide; Congo red,lithium chloride: CAS:7447-41-8; sodium chloride: CAS:7647-14-5; sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1; Congo red: CAS:573-58-0,,,,,gene deletion: full,,,RP,20153837,PubMed,10.1016/j.fgb.2010.02.004,,jruiz@ira.cinvestav.mx,rim9 is unaffected by any of the tested stresses,Cervantes-Chávez José Antonio,2010,Multi gene,Cervantes-Chavez-2010-Functional analysis,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3201,PHI:2603,UniProt,D2EAX7,,FN395061,,,,Rim20,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,leaf,pH response / involvement in endosomal targeting,,,Rim or Pal pathway,unaffected pathogenicity,no,,,,,wild type,,wild type,wild type,no,lithium chloride; sodium chloride; sodium lauryl sulfate; hydrogen peroxide; Congo red,lithium chloride: CAS:7447-41-8; sodium chloride: CAS:7647-14-5; sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1; Congo red: CAS:573-58-0,,,,,gene deletion: full,,,RP,20153837,PubMed,10.1016/j.fgb.2010.02.004,,jruiz@ira.cinvestav.mx,pH dependant sensitivity to stress,Cervantes-Chávez José Antonio,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3202,PHI:2604,UniProt,D2EAX8,,FN395062,,,,Rim13,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,leaf,pH response / encodes a putative calcium-activated cys-teine protease (calpain-like),,,Rim or Pal pathway,unaffected pathogenicity,no,,,,,wild type,,wild type,wild type,no,lithium chloride; sodium chloride; sodium lauryl sulfate; hydrogen peroxide; Congo red,lithium chloride: CAS:7447-41-8; sodium chloride: CAS:7647-14-5; sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1; Congo red: CAS:573-58-0,,,,,gene disruption,,,RP,20153837,PubMed,10.1016/j.fgb.2010.02.004,,jruiz@ira.cinvestav.mx,pH dependant sensitivity to stress,Cervantes-Chávez José Antonio,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3203,PHI:2605,UniProt,D2EAX9,,FN395063,,,,Rim23,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,leaf,pH response / putatively involved in endocytic trafficking,,,Rim or Pal pathway,unaffected pathogenicity,no,,,,,wild type,,wild type,wild type,no,lithium chloride; sodium chloride; sodium lauryl sulfate; hydrogen peroxide; Congo red,lithium chloride: CAS:7447-41-8; sodium chloride: CAS:7647-14-5; sodium lauryl sulfate: CAS:151-21-3; hydrogen peroxide: CAS:7722-84-1; Congo red: CAS:573-58-0,,,,,gene disruption,,,RP,20153837,PubMed,10.1016/j.fgb.2010.02.004,,jruiz@ira.cinvestav.mx,pH dependant sensitivity to stress,Cervantes-Chávez José Antonio,2010,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3204,PHI:2606,UniProt,I3QHH8,,JQ716919,,,,SKN7,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot (Citrus),eudicots,229630,Citrus x tangelo (related: tangelo),,,,leaf,stress-responsive transcription regulator,,,SKN7-mediated signaling pathway with HSK1 and HOG1,reduced virulence,,,,,,reduced; aberrant,,reduced,wild type,no,tert-butyl hydroperoxide (t-BHP); hydrogen peroxide; cumene hydroperoxide; glucose; sucrose; sorbitol; mannitol; sodium lauryl sulfate,tert-butyl hydroperoxide: CAS:75-91-2; hydrogen peroxide: CAS:7722-84-1; cumene hydroperoxide: CAS:80-15-9; glucose: CAS:50-99-7; sucrose: CAS:57-50-1; sorbitol: CAS:50-70-4; mannitol: CAS:69-65-8; sodium lauryl sulfate: CAS:151-21-3,,,,,gene deletion: full; gene complementation,,,RP,22902811,PubMed,10.1016/j.fgb.2012.07.006,,krchung@ufl.edu,"Mutational inactivation of the SKN7 gene resulted in fungal strains (D52 and D61) that display hypersensitivity to tert-butyl-hydroxyperoxide (t-BHP), H2O2, cumyl H2O2, glucose, sucrose, sorbitol, mannitol, and SDS. Mutants more resistant to the dicarboximide and phenylpyrrole fungicides.",Li-Hung Chen,2012,1 gene,Chen-2012-Roles for SKN7 respo,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3205,PHI:3510,UniProt,Q4P380,,EAK86491,,,521,Pmt4,chromosome 19,,,,,,5270,Ustilago maydis,559306,SG200; FB1; FB2,smut (maize),monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling; leaf,O-mannosyltransferase,,,MAP kinase,reduced virulence,,yes,yes,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22416226,PubMed,10.1371/journal.ppat.1002563,,joibecor@upo.es,no comments,Alfonso Fernandez-Alvarez,2012,1 gene,Fernandez-Alvarez-2012-Identification of O-,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3206,PHI:2608,UniProt,F8R4Y0,,AB725683,,,,ACRTS2,,,,,,,5599,Alternaria alternata,,HC1,leaf spot,eudicots,64884,Citrus jambhiri (related: rough lemon),,,,leaf,putative polyketide synthase,,,,reduced virulence,,,,,necrotic lesions,wild type,,wild type,wild type,no,,,,,,,gene disruption,,,RP,22835272,PubMed,10.1094/MPMI-06-12-0155-R,,kazuya@ag.kagawa-u.ac.jp,no comments,Y. Izumi,2012,1 gene,Izumi_MPMI-06-12-0155-R,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3207,PHI:2608,UniProt,F8R4Y0,,AB725683,,,,ACRTS2,,,,,,,5599,Alternaria alternata,,HC1,leaf spot,eudicots,64884,Citrus jambhiri (related: rough lemon),,,,leaf,putative polyketide synthase,,,,reduced virulence,,,,,necrotic lesions,wild type,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,22835272,PubMed,10.1094/MPMI-06-12-0155-R,,kazuya@ag.kagawa-u.ac.jp,no comments,Y. Izumi,2012,,,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3208,PHI:2609,UniProt,B2CQJ9,,ACB59235,,,G217B,VEA1,,,,,,,5037,Histoplasma capsulatum,,UC26,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,sexual development and toxin production,,,,reduced virulence,no,,,,,wild type,reduced,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,22841690,PubMed,10.1016/j.fgb.2012.07.001,,alan.smulian@uc.edu,Growth reduced at acidic pH,Meggan C. Laskowski-Peak,2012,1 gene,Laskowski-Peak-2012-VEA1 is required for,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3209,PHI:2611,UniProt,H9C592,,JQ234921,,,,CMLE,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,wilt (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker ss590,,,root,"3-carboxy-cis,cis-muconate lactonizing enzyme",,,b -ketoadipate pathway,loss of pathogenicity,,no,no,yes,,,,wild type,wild type,no,"ferulic acid; p-coumaric acid; vanillic acid; 4-hydroxybenzoic acid; p-hydroxybenzaldehyde; 2-propenoic acid, 3-phenyl-, (2E)-; catechol; lignin","ferulic acid: CAS:1135-24-6; p-coumaric acid: CAS:7400-08-0; vanillic acid: CAS:121-34-6; 4-hydroxybenzoic acid: CAS:99-96-7; p-hydroxybenzaldehyde: CAS:123-08-0; 2-propenoic   acid,   3-phenyl-,  (2E)-: CAS:140-10-3; catechol: CAS:120-80-9; lignin: CAS:9005-53-2",,,,,gene deletion: full; gene complementation,,,RP,22827542,PubMed,10.1111/J.1364-3703.2012.00818.X,,c.b.michielse@uni-muenster.de,Aromatic compunds affect the growth and conidiation of the deletion mutants,CAROLINE B. MICHIELSE,2012,1 gene,Michielse-2012-Degradation of aroma,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3210,PHI:2612,,no data found,GenBank,EU214531,,,VW4,cg-1,,,,,,,6303,Meloidogyne javanica,,VW4,,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,18393617,PubMed,10.1094/MPMI-21-5-0576,,vmwilliamson@ucdavis.edu,no comments,Cynthia A. Gleason,2008,1 gene,mpmi-21-5-0576,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3211,PHI:2613,UniProt,Q57XU3,GenBank,XP_846343,,,927/4,TbNTR,chromosome 7,,,,,,5691,Trypanosoma brucei,,427,African trypanosomiasis,,,,Lethal pathogen phenotype,,,,,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,18367671,PubMed,10.1073/pnas.0711014105,,s.r.wilkinson@qmul.ac.uk,Increased nitroheterocyclic drug resistance,Shane R. Wilkinson,2008,1 gene,Wilkinson-2008-A mechanism for cros,Batch020,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3212,PHI:2615,UniProt,A4L9V1,GenBank,AAZ73240.1,,,HT,ROP5,,,,,,,5811,Toxoplasma gondii,,RH,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),,,,,pseudokinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23144612,PubMed,10.1371/journal.ppat.1002992,,sibley@wustl.edu,no comments,MS Behnke,2012,1 gene,Free access from PubMed,Batch021,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3213,PHI:2616,UniProt,Q2L8G9,GenBank,DQ347777,,,FSLR2142,InlA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),BALB,,,gut,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23166492,PubMed,10.1371/journal.ppat.1003015,,sarah.dorazio@uky.edu,no comments,ENB Ghanem,2012,1 gene,Free access from PubMed,Batch021,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3214,PHI:2617,UniProt,Q59UY7,GenBank,EAK94325,,,SC5314,SEF1,,,,,,,5476,Candida albicans,,SN425,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,iron homeostasis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23133381,PubMed,10.1371/journal.ppat.1002956,,Suzanne.Noble@ucsf.edu,no comments,C Chen,2012,2 genes,Free access from PubMed,Batch021,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3215,PHI:2618,UniProt,Q5AP95,GenBank,EAL04662,,,SC5314,SFU1,chromosome 1,,,,,,5476,Candida albicans,,SN425,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,iron homeostasis,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23133381,PubMed,10.1371/journal.ppat.1002956,,Suzanne.Noble@ucsf.edu,no comments,C Chen,2012,,Free access from PubMed,Batch021,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3216,PHI:2619,UniProt,P18177,GenBank,CAA63562,,,VPI10463,tcdB,,,,,,,1496,Clostridioides difficile,,,diarrhea; pseudomembranous colitis; toxic megacolon,even-toed ungulates,9823,Sus scrofa (related: pig),York-Landrace,,,colon,"responsible for the fluid secretion, inflammation, and colonic tissue damage associated with disease",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236283,PubMed,10.1371/journal.ppat.1003072,,borden.lacy@vanderbilt.edu,Pathogen formerly called Clostridium difficile,NM Chumbler,2012,1 gene,Free access from PubMed,Batch021,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3217,PHI:2620,UniProt,Q9HWA4,GenBank,AE004846_1,,,PAO1,PprB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,septicemia,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,response regulator,,,PprB pathway,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation,,,RP,23209420,PubMed,10.1371/journal.ppat.1003052,,bentzman@imm.cnrs.fr,no comments,Sd Bentzmann,2012,1 gene,Free access from PubMed,Batch021,2013-01-01,MC,,,,,,,,,,,,,
,,Record 3218,PHI:2621,UniProt,D0ZWU0,GenBank,ACY88188,,,14028S,ssaV,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,Multi gene,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3219,PHI:2622,UniProt,Q7BVH7,GenBank,CAA12185,,,LT2,sseB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3220,PHI:2623,UniProt,Q8ZNG2,GenBank,AAL21188,,,LT2,sseL,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3221,PHI:2624,UniProt,P07637,GenBank,AAA27028,,,,aroA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3222,PHI:2625,UniProt,P65882,GenBank,AAL23186,,,LT2,purA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3223,PHI:2626,UniProt,D0ZWR8,GenBank,AAC44300,,,,spiC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3224,PHI:2627,UniProt,P74855,GenBank,CAA70535,,,LT2,ssaM,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3225,PHI:2628,UniProt,P21454,GenBank,CAA78760,,,TML R66,spvB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3226,PHI:2622,UniProt,Q7BVH7,GenBank,CAA12185,,,LT2,sseB,,,,,,PHI:2623,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3227,PHI:2624,UniProt,P07637,GenBank,AAA27028,,,,aroA,,,,,,PHI:2622,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3228,PHI:2622,UniProt,Q7BVH7,GenBank,CAA12185,,,LT2,sseB,,,,,,PHI:2625,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3229,PHI:2625,UniProt,P65882,GenBank,AAL23186,,,LT2,purA,,,,,,PHI:2622,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3230,PHI:2623,UniProt,Q8ZNG2,GenBank,AAL21188,,,LT2,sseL,,,,,,PHI:2628,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3231,PHI:2628,UniProt,P21454,GenBank,CAA78760,,,TML R66,spvB,,,,,,PHI:2623,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC S12023,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23236281,PubMed,10.1371/journal.ppat.1003070,,ajg60@cam.ac.uk,The parasite cannot egress the infected cells thus reduced virulence,A J Grant,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3232,PHI:2629,UniProt,O33336,GenBank,CCP45593,,,H37Rv,PptT,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,spleen; lung,4′-phosphopantetheinyl transferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23308068,PubMed,10.1371/journal.ppat.1003097,,Christian.Chalut@ipbs.fr (CC); Christophe.Guilhot@ipbs.fr,Mycobacterial multiplication in both immunodeficient and immunocompetent mice is dependent on the expression of PptT / PptT production is required for survival of M. tuberculosis during the chronic phase of infection.,C Leblanc,2012,1 gene,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3233,PHI:2629,UniProt,O33336,GenBank,CCP45593,,,H37Rv,PptT,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,spleen; lung,4′-phosphopantetheinyl transferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23308068,PubMed,10.1371/journal.ppat.1003097,,Christian.Chalut@ipbs.fr (CC); Christophe.Guilhot@ipbs.fr,Mycobacterial multiplication in both immunodeficient and immunocompetent mice is dependent on the expression of PptT / PptT production is required for survival of M. tuberculosis during the chronic phase of infection.,C Leblanc,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3234,PHI:2630,UniProt,B2HLZ8,GenBank,ACC40462,,,M,PPGK,,,,,,PHI:2631,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,polyphosphate glucokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23326232,PubMed,10.1371/journal.ppat.1003116,,sae2004@med.cornell.edu,no comments,J Marrero,2012,2 genes,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3235,PHI:2631,UniProt,I6Y8D3,GenBank,AFN48520,,,H37Rv,GLKA,,,,,,PHI:2630,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,glucokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23326232,PubMed,10.1371/journal.ppat.1003116,,sae2004@med.cornell.edu,no comments,J Marrero,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3236,PHI:2630,UniProt,B2HLZ8,GenBank,ACC40462,,,M,PPGK,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,polyphosphate glucokinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23326232,PubMed,10.1371/journal.ppat.1003116,,sae2004@med.cornell.edu,no comments,J Marrero,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3237,PHI:2631,UniProt,I6Y8D3,GenBank,AFN48520,,,H37Rv,GLKA,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,glucokinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23326232,PubMed,10.1371/journal.ppat.1003116,,sae2004@med.cornell.edu,no comments,J Marrero,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3238,PHI:2632,UniProt,Q2FIB5,EMBL,ABD20820.1,,,USA300,argH,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,community-acquired infection; nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,argininosuccinate lyase,,,arginine biosynthesis,reduced virulence,,,,,abscess,,,reduced,,no,,,,,,,gene disruption,,,AR,23209408,PubMed,10.1371/journal.ppat.1003033,,pfey@unmc.edu,no comments,A S Nuxoll,2012,Multi gene,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3239,PHI:2633,UniProt,Q2FK80,EMBL,ABD22932.1,,,USA300,argB,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,community-acquired infection; nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,acetylglutamate kinase,,,arginine biosynthesis,unaffected pathogenicity,,,,,abscess,,,wild type,,no,,,,,,,gene disruption,,,AR,23209408,PubMed,10.1371/journal.ppat.1003033,,pfey@unmc.edu,no comments,A S Nuxoll,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3240,PHI:2634,UniProt,A0A0H2XHH2,EMBL,abd21287,,,USA300,argF,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,community-acquired infection; nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,ornithine carbamoyltransferase,,,arginine biosynthesis,unaffected pathogenicity,,,,,abscess,,,wild type,,no,,,,,,,gene disruption,,,AR,23209408,PubMed,10.1371/journal.ppat.1003033,,pfey@unmc.edu,no comments,A S Nuxoll,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3241,PHI:2635,UniProt,Q2FFX4,EMBL,ABD22124.1,,,USA300,putA,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,community-acquired infection; nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,proline dehydrogenase,,,arginine biosynthesis,unaffected pathogenicity,,,,,abscess,,,reduced,,no,,,,,,,gene disruption,,,AR,23209408,PubMed,10.1371/journal.ppat.1003033,,pfey@unmc.edu,no comments,A S Nuxoll,2012,,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3242,PHI:2636,UniProt,Q8MYK0,GenBank,CAD32376,,,RH,TgCDPK3,,,,,,,5811,Toxoplasma gondii,,RH,toxoplasmic encephalitis,primates,9606,Homo sapiens (related: human),,,,foreskin fibroblast cell line,calcium dependent kinase 3,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23209419,PubMed,10.1371/journal.ppat.1003049,,gaarrizab@iupui.edu,The parasite cannot egress the infected cells thus reduced virulence,E Garrison,2012,1 gene,Free access from PubMed,Batch021,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3243,PHI:2637,UniProt,O51712,GenBank,AAC67109,,,B31,RpoS,,,,,,,139,Borreliella burgdorferi,224326,B31,Lyme disease,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,heart; joint; skin,RpoS regulates essential virulence factors,,,RpoN-RpoS pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,23300893,PubMed,10.1371/journal.pone.0053212,,fliang@ve tmed.lsu.ed u,tibiotarsal joint,Q Xu 2013,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3244,PHI:2638,UniProt,Q4X099,GenBank,EAL93716,,,Af293,Ilv3A,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,dihydroxyacid dehydratase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23028460,PubMed,10.1371/journal.pone.0043559,,mike.bromley@man chester.ac.uk,no comments,J D Oliver 2013,2012,2 genes,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3245,PHI:2639,UniProt,Q4WK65,GenBank,XP_750105,,,Af293,Ilv3B,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,dihydroxyacid dehydratase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23028460,PubMed,10.1371/journal.pone.0043559,,mike.bromley@man chester.ac.uk,no comments,J D Oliver 2013,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3246,PHI:2638,UniProt,Q4X099,GenBank,EAL93716,,,Af293,Ilv3A,,,,,,PHI:2639,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,dihydroxyacid dehydratase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23028460,PubMed,10.1371/journal.pone.0043559,,mike.bromley@man chester.ac.uk,no comments,J D Oliver 2013,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3247,PHI:2639,UniProt,Q4WK65,GenBank,XP_750105,,,Af293,Ilv3B,,,,,,PHI:2638,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,dihydroxyacid dehydratase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23028460,PubMed,10.1371/journal.pone.0043559,,mike.bromley@man chester.ac.uk,no comments,J D Oliver 2013,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3248,PHI:2640,UniProt,C4XXN5,GenBank,EEQ36584,,,ATCC42720,CNB1,,,,,,,36911,Clavispora lusitaniae,306902,ATCC 42720,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,calcium-activated protein phosphatase,,,calcineurin pathway,reduced virulence,,,,,,,,reduced,,no,sodium lauryl sulfate (SDS); 7-diethylamino-4-methylcoumarin (CFW); Congo red (CR),sodium lauryl sulfate: CAS:151-21-3; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0,,,,,gene deletion: full,,,RP,22952924,PubMed,10.1371/journal.pone.0044192,,heitm0 01@duke.e du (JH); joseph.chen@ duke.edu (Y-LC ),"The cnb1 , but not crz1 , mutants are sensitive to SDS, CFW, and CR. Pathogen formerly called Candida lusitaniae.",J Zhang 2013,2012,2 genes,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3249,PHI:2641,UniProt,C4Y985,GenBank,EEQ40635,,,ATCC 42720,CRZ1,,,,,,,36911,Clavispora lusitaniae,306902,ATCC 42720,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,calcium-activated protein phosphatase,,,calcineurin pathway,reduced virulence,,,,,,,,reduced,,no,sodium lauryl sulfate (SDS); 7-diethylamino-4-methylcoumarin (CFW); Congo red (CR),sodium lauryl sulfate: CAS:151-21-3; 7-diethylamino-4-methylcoumarin: CAS:91-44-1; Congo red: CAS:573-58-0,,,,,gene deletion: full,,,RP,22952924,PubMed,10.1371/journal.pone.0044192,,heitm0 01@duke.e du (JH); joseph.chen@ duke.edu (Y-LC ),"The cnb1 , but not crz1 , mutants are sensitive to SDS, CFW, and CR. Pathogen formerly called Candida lusitaniae.",J Zhang 2013,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3250,PHI:2642,UniProt,D0Z9I9,GenBank,ACY84965,,,EIB202,FliC,,,,,,,636,Edwardsiella tarda,,H1,edwardsiellosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,flagellin protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23024793,PubMed,10.1371/journal.pone.0045070,,xhzh ang@ouc.edu.c n,no comments,Y He 2013,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3251,PHI:2643,UniProt,A4HTK3,GenBank,CAM65755,,,JPCM5,CFAS,chromosome 8,,,,,,5671,Leishmania infantum,435258,JPCM5,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,cyclopropane fatty acid synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23251490,PubMed,10.1371/journal.pone.0051300,,deborah.smith@york .ac.uk,"The complemented strain grew well, but the attentuated virulence was not restored to wild type",S O Oyola 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3252,PHI:2644,UniProt,P0AA28,GenBank,BAA00903,,,LT2,thioredoxin 1,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,food poisoning,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,redox activity,,,,reduced virulence,,,,,,,,,,no,ascorbic acid; chloramphenicol; cupric chloride anhydrous,ascorbic acid: CAS:50-81-7; chloramphenicol: CAS:56-75-7; cupric chloride anhydrous: CAS:7447-39-4,,,,,gene deletion: full; gene complementation,,,RP,23028994,PubMed,10.1371/journal.pone.0045417,,Mikae l.Rhen@ki.s e,Ascorbic acid and chloramphenicol reduced the effects of pathogenicity of the mutants,X Sem 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3253,PHI:2644,UniProt,P0AA28,GenBank,BAA00903,,,LT2,thioredoxin 1,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,food poisoning,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,redox activity,,,,reduced virulence,,,,,,,,,,no,ascorbic acid; chloramphenicol; cupric chloride anhydrous,ascorbic acid: CAS:50-81-7; chloramphenicol: CAS:56-75-7; cupric chloride anhydrous: CAS:7447-39-4,,,,,chemical complementation,,,RP,23028994,PubMed,10.1371/journal.pone.0045417,,Mikae l.Rhen@ki.s e,"Virulence of the thioredoxin 1 mutant was restored by trans -complementation with redox-active variants of thioredoxin 1 or, surprisingly, by exposing the thioredoxin 1 mutant to sublethal concentrations of the disulphide catalyst copper chloride prior to infection",X Sem 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3254,PHI:2645,UniProt,Q7WP75,GenBank,CAE31309,,,RB50,ClpV,,,,,,,518,Bordetella bronchiseptica,257310,RB50,bordetellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,nasal cavity; trachea; lung,translocation of T6SS effector proteins essential for virulence,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,23071529,PubMed,10.1371/journal.pone.0045892,,Harvil l@psu.edu,no comments,L S Weyrich 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3255,PHI:2646,UniProt,E0IWR8,GenBank,ADT75274,,,W,MliC,,,,,,,562,Escherichia coli,,CH2,colibacillosis; cellulitis; swollen head syndrome,birds,9031,Gallus gallus (related: chicken),,,,,lysozyme inhibitor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23049900,PubMed,10.1371/journal.pone.0045954,,Chris. Michiels@b iw.kuleuven.be,no comments,L Vanderkelen 2012,2012,Multi genes,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3256,PHI:2647,UniProt,A1A7T3,GenBank,ABI99722,,,APEC O1,ivy,,,,,,,562,Escherichia coli,,CH2,colibacillosis; cellulitis; swollen head syndrome,birds,9031,Gallus gallus (related: chicken),,,,,lysozyme inhibitor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23049900,PubMed,10.1371/journal.pone.0045954,,Chris. Michiels@b iw.kuleuven.be,no comments,L Vanderkelen 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3257,PHI:2648,UniProt,P76002,GenBank,NP_415696,,,K-12 substr. MG1655,pliG,,,,,,,562,Escherichia coli,,CH2,colibacillosis; cellulitis; swollen head syndrome,birds,9031,Gallus gallus (related: chicken),,,,,lysozyme inhibitor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23049900,PubMed,10.1371/journal.pone.0045954,,Chris. Michiels@b iw.kuleuven.be,no comments,L Vanderkelen 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3258,PHI:2646,UniProt,E0IWR8,GenBank,ADT75274,,,W,MliC,,,,,,PHI:2647,562,Escherichia coli,,CH2,colibacillosis; cellulitis; swollen head syndrome,birds,9031,Gallus gallus (related: chicken),,,,,lysozyme inhibitor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23049900,PubMed,10.1371/journal.pone.0045954,,Chris. Michiels@b iw.kuleuven.be,no comments,L Vanderkelen 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3259,PHI:2647,UniProt,A1A7T3,GenBank,ABI99722,,,APEC O1,ivy,,,,,,PHI:2646,562,Escherichia coli,,CH2,colibacillosis; cellulitis; swollen head syndrome,birds,9031,Gallus gallus (related: chicken),,,,,lysozyme inhibitor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23049900,PubMed,10.1371/journal.pone.0045954,,Chris. Michiels@b iw.kuleuven.be,no comments,L Vanderkelen 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3260,PHI:2649,UniProt,Q5ALT5,GenBank,EAL03648,,,SC5314,Msb2,chromosome 2,,,,,,5476,Candida albicans,,CAI4,oral candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,tongue; hypoglossal nerve,mucin,,,Cek1 MAPK pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23139737,PubMed,10.1371/journal.pone.0046020,,edgerto@buffalo. edu,no comments,S Puri 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3261,PHI:2650,UniProt,B5R579,GenBank,CAR34083,,,P125109,BamB,,,,,,,28901,Salmonella enterica,1147754,subsp. enterica serovar Enteritidis strain LA5,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,folding and insertion of b-barrel proteins in the outer membrane of gram-negative bacteria is mediated by the BAM complex,,,,reduced virulence,,,,,,,,,,no,vancomycin; rifampin; erythromycin; novobiocin; bacitracin,vancomycin: CAS:1404-90-6; rifampin: CAS:13292-46-1; erythromycin: CAS:114-07-8; novobiocin: CAS:303-81-1; bacitracin: CAS:1405-87-4,,,,,gene deletion: full; gene complementation,,,RP,23144780,PubMed,10.1371/journal.pone.0046050,,ipayant@tours.inra. fr,The deletion mutant does not show any enhanced susceptibility to antibiotics,F Namdari 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3262,PHI:2650,UniProt,B5R579,GenBank,CAR34083,,,P125109,BamB,,,,,,,28901,Salmonella enterica,1147754,subsp. enterica serovar Enteritidis strain LA5,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,folding and insertion of b-barrel proteins in the outer membrane of gram-negative bacteria is mediated by the BAM complex,,,,reduced virulence,,,,,,,,,,no,vancomycin; rifampin; erythromycin; novobiocin; bacitracin,vancomycin: CAS:1404-90-6; rifampin: CAS:13292-46-1; erythromycin: CAS:114-07-8; novobiocin: CAS:303-81-1; bacitracin: CAS:1405-87-4,,,,,gene mutation: characterised,,,RP,23144780,PubMed,10.1371/journal.pone.0046050,,ipayant@tours.inra. fr,The deletion mutant does not show any enhanced susceptibility to antibiotics,F Namdari 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3263,PHI:2651,UniProt,Q8ZQ52,GenBank,AAL20029,,,LT2,yedX,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,cyclic amidohydrolase that hydrolyses 5-hydroxyisourate (5-HIU),,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,23284609,PubMed,10.1371/journal.pone.0046675,,rastru@unimelb.edu.au,no comments,S C Hennebry 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3264,PHI:2651,UniProt,Q8ZQ52,GenBank,AAL20029,,,LT2,yedX,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,food poisoning,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen,cyclic amidohydrolase that hydrolyses 5-hydroxyisourate (5-HIU),,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,23284609,PubMed,10.1371/journal.pone.0046675,,rastru@unimelb.edu.au,The bacterial load detected in the faeces of mutant infected chickens was significantly reduced when compared to the load of S. Typhimurium SL1344. Thus affecting dissemination,S C Hennebry 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3265,PHI:2652,UniProt,Q5KQZ9,GenBank,BAD86762,,,NTUH-K2044,magA,,,,,,,573,Klebsiella pneumoniae,484021,NTUH-K2044,urinary tract infection; nosocomial pneumonia; abdominal infection,rodents,10090,Mus musculus (related: house mouse),BALB/cBy,,,,contributes to K1 capsular polysaccharide (CPS) biosynthesis,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,23118860,PubMed,10.1371/journal.pone.0046783,,wangjt@ntu.edu.tw,no comments,Tzu-Lung Lin 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3266,PHI:2653,UniProt,G2Y3E7,GenBank,CCD47187,,,T4,bcvel1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,regulatory protein linking light signals with development and secondary metabolism,,,,reduced virulence,yes,no,,yes,,increased; aberrant,wild type,wild type,wild type,no,hydrogen peroxide,CAS:7722-84-1,,,,,gene deletion: full; gene complementation,,,RP,23118899,PubMed,10.1371/journal.pone.0047840,,Bettina.Tudzynski@uni-muenster.de,bcvel1 mutant were significantly affected when the strains were grown on medium supplemented with 7.5 M hydrogen peroxide in continuous light,Julia Schumacher 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3267,PHI:2653,UniProt,G2Y3E7,GenBank,CCD47187,,,T4,bcvel1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,regulatory protein linking light signals with development and secondary metabolism,,,,reduced virulence,yes,no,,yes,,increased; aberrant,wild type,wild type,wild type,no,hydrogen peroxide,CAS:7722-84-1,,,,,gene deletion: full; gene complementation,,,RP,23118899,PubMed,10.1371/journal.pone.0047840,,Bettina.Tudzynski@uni-muenster.de,bcvel1 mutant were significantly affected when the strains were grown on medium supplemented with 7.5 M hydrogen peroxide in continuous light,Julia Schumacher 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3268,PHI:2653,UniProt,G2Y3E7,GenBank,CCD47187,,,T4,bcvel1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,berry,regulatory protein linking light signals with development and secondary metabolism,,,,reduced virulence,yes,no,,yes,,increased; aberrant,wild type,wild type,wild type,no,hydrogen peroxide,CAS:7722-84-1,,,,,gene deletion: full; gene complementation,,,RP,23118899,PubMed,10.1371/journal.pone.0047840,,Bettina.Tudzynski@uni-muenster.de,bcvel1 mutant were significantly affected when the strains were grown on medium supplemented with 7.5 M hydrogen peroxide in continuous light,Julia Schumacher 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3269,PHI:2654,UniProt,Q59VF3,GenBank,EAK94485,,,SC5314,"DUR1,2",chromosome 1,,,,,,5476,Candida albicans,,A72,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; brain,urea metabolism,,,"IL-1 inflammatory pathway, IL-15 signaling, MAP kinase signaling, and the alternative complement pathway",reduced virulence,,,,,,,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,23144764,PubMed,10.1371/journal.pone.0048475,,drobe rts@helix.nih. gov,no comments,D H M L P N varathna 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3270,PHI:2655,UniProt,K1C7N5,GenBank,EKA39411,,,ATCC700888,lon,,,,,,,287,Pseudomonas aeruginosa,,H103,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,cytoplasmic serine protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,RP,23145092,PubMed,10.1371/journal.pone.0049123,,bob@hancocklab.com,no comments,E B M Breidenstein 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3271,PHI:2655,UniProt,K1C7N5,GenBank,EKA39411,,,ATCC700888,lon,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,cytoplasmic serine protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,RP,23145092,PubMed,10.1371/journal.pone.0049123,,bob@hancocklab.com,no comments,E B M Breidenstein 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3272,PHI:2655,UniProt,K1C7N5,GenBank,EKA39411,,,ATCC700888,lon,,,,,,,287,Pseudomonas aeruginosa,,H103,nosocomial infection,rodents,10114,Rattus (related: rat),,,,lung,cytoplasmic serine protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,RP,23145092,PubMed,10.1371/journal.pone.0049123,,bob@hancocklab.com,no comments,E B M Breidenstein 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3273,PHI:2655,UniProt,K1C7N5,GenBank,EKA39411,,,ATCC700888,lon,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10114,Rattus (related: rat),,,,lung,cytoplasmic serine protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,RP,23145092,PubMed,10.1371/journal.pone.0049123,,bob@hancocklab.com,no comments,E B M Breidenstein 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3274,PHI:2656,UniProt,D0ZPP5,GenBank,ACY89276,,,14028S,pmrF,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain JSG210,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,Peyer's gland,4-amino-4-deoxy-L-arabinose (Ara4N) production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23166721,PubMed,10.1371/journal.pone.0049588,,gunn.43@osu.edu,Attenuated virulence seen only in mice infected via the oral not the IP route,K L Strandberg 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3275,PHI:2657,UniProt,A9CFS9,GenBank,AAK89532,,,C58,HspL,,,,,,,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,functions as a VirB8 chaperone to promote T4SS-mediated DNA transfer,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,no comments,Y L Tsai,2012,Multi genes,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3276,PHI:2658,UniProt,A9CKC3,GenBank,AAK86192,,,C58,hspC,,,,,,,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,alpha-crystallin-type small heat shock proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,no comments,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3277,PHI:2659,UniProt,Q7D412,GenBank,AAK90427,,,C58,hspAT1,,,,,,,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,alpha-crystallin-type small heat shock proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,no comments,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3278,PHI:2660,UniProt,Q7D321,GenBank,AAK90824,,,C58,hspAT2,,,,,,,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,alpha-crystallin-type small heat shock proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,no comments,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3279,PHI:2658,UniProt,A9CKC3,GenBank,AAK86192,,,C58,hspC,,,,,,PHI:2660,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,alpha-crystallin-type small heat shock proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,no comments,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3280,PHI:2660,UniProt,Q7D321,GenBank,AAK90824,,,C58,hspAT2,,,,,,PHI:2658,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,alpha-crystallin-type small heat shock proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,no comments,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3281,PHI:2657,UniProt,A9CFS9,GenBank,AAK89532,,,C58,HspL,,,,,,PHI:2658,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,functions as a VirB8 chaperone to promote T4SS-mediated DNA transfer,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,Overexpression of each of sHsps in D 4sHsps was able to restore the tumorigenesis efficiency at wildtype-like levels,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3282,PHI:2657,UniProt,A9CFS9,GenBank,AAK89532,,,C58,HspL,,,,,,PHI:2659,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,functions as a VirB8 chaperone to promote T4SS-mediated DNA transfer,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,Overexpression of each of sHsps in D 4sHsps was able to restore the tumorigenesis efficiency at wildtype-like levels,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3283,PHI:2657,UniProt,A9CFS9,GenBank,AAK89532,,,C58,HspL,,,,,,PHI:2660,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,functions as a VirB8 chaperone to promote T4SS-mediated DNA transfer,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,Overexpression of each of sHsps in D 4sHsps was able to restore the tumorigenesis efficiency at wildtype-like levels,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3284,PHI:2658,UniProt,A9CKC3,GenBank,AAK86192,,,C58,hspC,,,,,,PHI:2657,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,alpha-crystallin-type small heat shock proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,Overexpression of each of sHsps in D 4sHsps was able to restore the tumorigenesis efficiency at wildtype-like levels,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3285,PHI:2659,UniProt,Q7D412,GenBank,AAK90427,,,C58,hspAT1,,,,,,PHI:2657,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,alpha-crystallin-type small heat shock proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,Overexpression of each of sHsps in D 4sHsps was able to restore the tumorigenesis efficiency at wildtype-like levels,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3286,PHI:2660,UniProt,Q7D321,GenBank,AAK90824,,,C58,hspAT2,,,,,,PHI:2657,358,Agrobacterium tumefaciens,,NT1RE,crown gall,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,alpha-crystallin-type small heat shock proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23185409,PubMed,10.1371/journal.pone.0049685,,emlai@gate.sinica.edu. tw,Overexpression of each of sHsps in D 4sHsps was able to restore the tumorigenesis efficiency at wildtype-like levels,Y L Tsai,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3287,PHI:2661,UniProt,Q4X0J5,GenBank,EAL93620,,,Af293,MedA,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,developmental regulator,,,,reduced virulence,,,,,,aberrant,,aberrant,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,23185496,PubMed,10.1371/journal.pone.0049959,,donald.sheppard@mcgill.ca,no comments,Q A Abdallah 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3288,PHI:2662,UniProt,A4VZ16,GenBank,ABP91355,,,98HAH33,HP0197,,,,,,,1307,Streptococcus suis,391295,05ZY,meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,surface protective antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23226442,PubMed,10.1371/journal.pone.0050987,,jml8328@126.com,no comments,A Zhang 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3289,PHI:2662,UniProt,A4VZ16,GenBank,ABP91355,,,98HAH33,HP0197,,,,,,,1307,Streptococcus suis,391295,05ZY,meningitis,even-toed ungulates,9823,Sus scrofa (related: pig),,,,blood,surface protective antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23226442,PubMed,10.1371/journal.pone.0050987,,jml8328@126.com,no comments,A Zhang 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3290,PHI:2663,UniProt,Q4DDC5,GenBank,XP_812391,,,CL Brener,delta-amastin,,,,,,,5693,Trypanosoma cruzi,353153,CL Brener,Chagas disease,rodents,10090,Mus musculus (related: house mouse),A/JUnib,,,liver,surface glycoprotein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23272170,PubMed,10.1371/journal.pone.0051804,,ramortara@unifesp.br,no comments,M C Cruz 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3291,PHI:2664,UniProt,C5AIS7,GenBank,ACR31807,,,BGR1,tofM,,,,,,,337,Burkholderia glumae,1417989,336gr-1,panicle blight,monocots,4530,Oryza sativa (related: rice),,,,panicle,produce toxoflavin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23284909,PubMed,10.1371/journal.pone.0052150,,jham@agcenter.lsu.edu,no comments,R Chen 2012,2012,Multi genes,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3292,PHI:2665,UniProt,Q4VSJ8,GenBank,AAV52805,,,BGR1,tofI,,,,,,,337,Burkholderia glumae,1417989,336gr-1,panicle blight,monocots,4530,Oryza sativa (related: rice),,,,panicle,produce toxoflavin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23284909,PubMed,10.1371/journal.pone.0052150,,jham@agcenter.lsu.edu,no comments,R Chen 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3293,PHI:2666,UniProt,Q4VSJ9,GenBank,AAV52804,,,BGR1,tofR,,,,,,,337,Burkholderia glumae,1417989,336gr-1,panicle blight,monocots,4530,Oryza sativa (related: rice),,,,panicle,produce toxoflavin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23284909,PubMed,10.1371/journal.pone.0052150,,jham@agcenter.lsu.edu,no comments,R Chen 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3294,PHI:2664,UniProt,C5AIS7,GenBank,ACR31807,,,BGR1,tofM,,,,,,PHI:2665; PHI:2666,337,Burkholderia glumae,1417989,336gr-1,panicle blight,monocots,4530,Oryza sativa (related: rice),,,,panicle,produce toxoflavin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23284909,PubMed,10.1371/journal.pone.0052150,,jham@agcenter.lsu.edu,no comments,R Chen 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3295,PHI:2665,UniProt,Q4VSJ8,GenBank,AAV52805,,,BGR1,tofI,,,,,,PHI:2666; PHI:2664,337,Burkholderia glumae,1417989,336gr-1,panicle blight,monocots,4530,Oryza sativa (related: rice),,,,panicle,produce toxoflavin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23284909,PubMed,10.1371/journal.pone.0052150,,jham@agcenter.lsu.edu,no comments,R Chen 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3296,PHI:2666,UniProt,Q4VSJ9,GenBank,AAV52804,,,BGR1,tofR,,,,,,PHI:2665; PHI:2664,337,Burkholderia glumae,1417989,336gr-1,panicle blight,monocots,4530,Oryza sativa (related: rice),,,,panicle,produce toxoflavin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23284909,PubMed,10.1371/journal.pone.0052150,,jham@agcenter.lsu.edu,no comments,R Chen 2012,2012,,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3297,PHI:2667,UniProt,H6SB05,GenBank,CCE36717,,,UT205,PPE18,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung; liver,PPE18 was found to selectively downregulate the proin-flammatory and Th1-type immune response,,,p38 mitogen activated protein kinase (MAPK) pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,23300718,PubMed,10.1371/journal.pone.0052601,,sangita@cdfd.org.in; sangitacdfd@gmail.c om,no comments,K H Bhat 2012,2012,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3298,PHI:2668,UniProt,G2Y3E7,GenBank,CCD47187,,,T4,bcvel1,,,,,,,40559,Botrytis cinerea,,1750,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Caruso,,,leaf,regulatory protein linking light signals with development and secondary metabolism,,,p38 mitogen activated protein kinase (MAPK) pathway,reduced virulence,,,,,,aberrant,,,,no,fenhexamid,"fenhexamid: CHEBI:9242, CAS:126833-17-8",,,,,gene deletion: full,,,RP,23308280,PubMed,10.1371/journal.pone.0053729,,viaud@versailles.inra. fr,bcvel1 mutants was accompanied by the inability of the mutant to grow on medium containing fenhexamid,J Schumacher 2013,2013,1 gene,Free access from PubMed,Batch022,2013-02-01,MC,,,,,,,,,,,,,
,,Record 3299,PHI:2669,UniProt,Q9I1R1,GenBank,AE004647_3,,,PAO1,PA2206,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,bony fishes,7955,Danio rerio (related: zebrafish),AB,,,embryo,LysR-type transcriptional regulators,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide,CAS:7722-84-1,,,,,gene mutation: characterised,,,RP,23382903,PubMed,10.1371/journal.pone.0054479,,f.ogara@ucc .ie,PA2206 was found to be required for tolerance to H 2 O 2 in vitro,F J Reen,2013,1 gene,Free access from PubMed,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3300,PHI:2670,UniProt,A3M486,GenBank,ABO11730,,,ATCC 17978,tssM,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),,,,,part of type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,23365692,PubMed,10.1371/journal.pone.0055142,,mfeldman@ualberta.ca,no comments,B S Weber,2013,1 gene,Free access from PubMed,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3301,PHI:2670,UniProt,A3M486,GenBank,ABO11730,,,ATCC 17978,tssM,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,part of type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,23365692,PubMed,10.1371/journal.pone.0055142,,mfeldman@ualberta.ca,no comments,B S Weber,2013,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3302,PHI:2670,UniProt,A3M486,GenBank,ABO11730,,,ATCC 17978,tssM,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver,part of type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,23365692,PubMed,10.1371/journal.pone.0055142,,mfeldman@ualberta.ca,no comments,B S Weber,2013,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3303,PHI:2671,UniProt,P13041,GenBank,VRPR_SALTY,,,LT2,spvR,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,Multi genes,Free access from PubMed,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3304,PHI:2672,UniProt,P0A2P8,GenBank,CRA_SALTY,,,LT2,fruR,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3305,PHI:2673,UniProt,P64394,GenBank,IHFB_SALTY,,,LT2,himD,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3306,PHI:2674,UniProt,P0DM78,GenBank,PHOP_SALTY,,,LT2,phoP,,,,,,PHI:2675,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3307,PHI:2675,UniProt,P0DM80,GenBank,PHOQ_SALTY,,,LT2,phoQ,,,,,,PHI:2674,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3308,PHI:2676,UniProt,Q8ZPP5,GenBank,Q8ZPP5_SALTY,,,LT2,ssrA,,,,,,PHI:2677,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3309,PHI:2677,UniProt,Q7CQM5,GenBank,Q7CQM5_SALTY,,,LT2,ssrB,,,,,,PHI:2676,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3310,PHI:2678,UniProt,P40676,GenBank,SLYA_SALTY,,,LT2,slyA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3311,PHI:2679,UniProt,Q7CQF1,GenBank,Q7CQF1_SALTY,,,LT2,hnr,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3312,PHI:2680,UniProt,P0A2F0,GenBank,RPOE_SALT,,,LT2,rpoE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3313,PHI:2681,UniProt,P0A2G1,GenBank,SSRP_SALTY,,,LT2,smpB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3314,PHI:2682,UniProt,P69917,GenBank,CSRA_SALTY,,,LT2,csrA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3315,PHI:2683,UniProt,P0DM81,GenBank,RPOS_SALTY,,,LT2,rpoS,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3316,PHI:2684,UniProt,P0A2T6,GenBank,CRP_SALTY,,,LT2,crp,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3317,PHI:2685,UniProt,P0AA19,GenBank,OMPR_SALTY,,,LT2,ompR,,,,,,PHI:2686,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3318,PHI:2686,UniProt,P08982,GenBank,ENVZ_SALTY,,,LT2,envZ,,,,,,PHI:2685,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3319,PHI:2687,UniProt,P0A1R0,GenBank,HFQ_SALTY,,,LT2,hfq,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,regulators of systemic infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19229334,PubMed,10.1371/journal.ppat.1000306,,heffronf@ohsu.edu,no comments,H Yoon,2009,,,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3320,PHI:2688,UniProt,Q3BQL2,GenBank,CAJ24951,,,85-10,XopL,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,novel E3 ubiquitin ligase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,23359647,PubMed,10.1371/journal.ppat.1003121,,ulla.bonas@genetik.uni-halle.de,no comments,A U Singer,2013,1 gene,Free access from PubMed,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3321,PHI:2689,UniProt,Q6E9X8,GenBank,AAS84970,,,NRRL 33064,ActA,,,,,,,1639,Listeria monocytogenes,393132,LO28,listeriosis,rodents,10090,Mus musculus (related: house mouse),KI E16P,,,spleen; liver; mesenteric lymph node; intestine; colon,virulence determinant; enabling actin polymerization,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23382675,PubMed,10.1371/journal.ppat.1003131,,marc. lecuit@pas teur.fr,ActA plays a key role in persistence within the host and in transmission from the host back to the environment,L Travier,2013,1 gene,Free access from PubMed,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3322,PHI:2690,UniProt,P08191,GenBank,CAA29156,,,K12,FimH,,,,,,,562,Escherichia coli,591946,LF82,Crohn's disease,rodents,10090,Mus musculus (related: house mouse),FVB/N; CEABAC10,,,gut,adhesion,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,RP,23358328,PubMed,10.1371/journal.ppat.1003141,,nicolas.barnich@u -clermont1.fr,no comments,N Dreux,2013,1 gene,Free access from PubMed,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3323,PHI:2691,UniProt,Q6FUI3,GenBank,XP_446111,,,CBS 138,IRE1,,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen,transmembrane kinase/endoribonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23382685,PubMed,10.1371/journal.ppat.1003160,,taiga-m@nagasaki-u.ac.jp,no comments,T Miyazaki,2013,1 gene,Free access from PubMed,Batch023,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3324,PHI:2692,UniProt,E0W547,GenBank,AEK80452,,,P7064,Avh5,,,,,,,67593,Phytophthora sojae,,,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,root,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23075041,PubMed,10.1094/MPMI-07-12-0184-R,,capellut@vt.edu,mutation in RXLR motif stopped Avh5 protein uptake into soybean root cells.,F Sun,2013,1 gene,Sun-2013-Structural Basis for,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3325,PHI:2693,UniProt,F0XP73,GenBank,EFX00255,,,kw1407,GcABC-G1,,,,,,,226899,Leptographium clavigerum,655863,kw1407,,seed plants,3339,Pinus contorta (related: lodgepole pine),,,,whole plant,ABC efflux transporter,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full,,,RP,23252416,PubMed,10.1111/nph.12063,,colette.breuil@ubc.ca,changed species name from 'Grosmannia clavigera' to 'Leptographium clavigerum' for 4.17,Y Wang,2013,1 gene,Wang-2013-A specialized ABC ef,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3326,PHI:2694,UniProt,Q6D000,GenBank,CAG76898,,,SCRI1043,rsmB,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,tuber rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),cv. Maris Piper,,,tuber,modulates plant cell wall-degrading enzymes,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23113713,PubMed,10.1094/MPMI-09-12-0210-R,,gpcs2@cam.ac.uk,no comments,M F Cubitt,2013,2 genes,Cubitt-2013-A Metabolic Regulato,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3327,PHI:2695,UniProt,Q6CZA0,GenBank,CAG77150,,,SCRI1043,metJ,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,tuber rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),cv. Maris Piper,,,tuber,repressor of the methionine biosynthesis regulon,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23113713,PubMed,10.1094/MPMI-09-12-0210-R,,gpcs2@cam.ac.uk,no comments,M F Cubitt,2013,,Cubitt-2013-A Metabolic Regulato,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3328,PHI:2694,UniProt,Q6D000,GenBank,CAG76898,,,SCRI1043,rsmB,,,,,,PHI:2695,29471,Pectobacterium atrosepticum,218491,SCRI 1043,tuber rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),cv. Maris Piper,,,tuber,modulates plant cell wall-degrading enzymes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23113713,PubMed,10.1094/MPMI-09-12-0210-R,,gpcs2@cam.ac.uk,no comments,M F Cubitt,2013,,Cubitt-2013-A Metabolic Regulato,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3329,PHI:2695,UniProt,Q6CZA0,GenBank,CAG77150,,,SCRI1043,metJ,,,,,,PHI:2694,29471,Pectobacterium atrosepticum,218491,SCRI 1043,tuber rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),cv. Maris Piper,,,tuber,repressor of the methionine biosynthesis regulon,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23113713,PubMed,10.1094/MPMI-09-12-0210-R,,gpcs2@cam.ac.uk,no comments,M F Cubitt,2013,,Cubitt-2013-A Metabolic Regulato,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3330,PHI:2696,UniProt,I1VGT7,GenBank,AFI43935,,,UK7,NIP2,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Ingrid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,Multi genes,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3331,PHI:2697,UniProt,I1VGT8,GenBank,AFI43936,,,UK7,NIP3,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Ingrid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3332,PHI:2698,UniProt,Q02039,GenBank,ABR92629,,,,NIP1,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Ingrid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3333,PHI:2696,UniProt,I1VGT7,GenBank,AFI43935,,,UK7,NIP2,,,,,,PHI:2698,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Ingrid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3334,PHI:2698,UniProt,Q02039,GenBank,ABR92629,,,,NIP1,,,,,,PHI:2696,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Ingrid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3335,PHI:2696,UniProt,I1VGT7,GenBank,AFI43935,,,UK7,NIP2,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Atlas,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3336,PHI:2697,UniProt,I1VGT8,GenBank,AFI43936,,,UK7,NIP3,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Atlas,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3337,PHI:2698,UniProt,Q02039,GenBank,ABR92629,,,,NIP1,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Atlas,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3338,PHI:2696,UniProt,I1VGT7,GenBank,AFI43935,,,UK7,NIP2,,,,,,PHI:2698,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Atlas,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3339,PHI:2698,UniProt,Q02039,GenBank,ABR92629,,,,NIP1,,,,,,PHI:2696,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Atlas,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3340,PHI:2696,UniProt,I1VGT7,GenBank,AFI43935,,,UK7,NIP2,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Atlas 46,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3341,PHI:2697,UniProt,I1VGT8,GenBank,AFI43936,,,UK7,NIP3,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Atlas 46,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3342,PHI:2698,UniProt,Q02039,GenBank,ABR92629,,,,NIP1,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Atlas 46,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3343,PHI:2696,UniProt,I1VGT7,GenBank,AFI43935,,,UK7,NIP2,,,,,,PHI:2698,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Atlas 46,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3344,PHI:2698,UniProt,Q02039,GenBank,ABR92629,,,,NIP1,,,,,,PHI:2696,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Atlas 46,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3345,PHI:2696,UniProt,I1VGT7,GenBank,AFI43935,,,UK7,NIP2,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Turk,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3346,PHI:2697,UniProt,I1VGT8,GenBank,AFI43936,,,UK7,NIP3,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Turk,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3347,PHI:2698,UniProt,Q02039,GenBank,ABR92629,,,,NIP1,,,,,,,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Turk,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3348,PHI:2696,UniProt,I1VGT7,GenBank,AFI43935,,,UK7,NIP2,,,,,,PHI:2698,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Turk,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3349,PHI:2698,UniProt,Q02039,GenBank,ABR92629,,,,NIP1,,,,,,PHI:2696,914237,Rhynchosporium commune,,UK7,leaf scald (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Turk,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,22712509,PubMed,10.1094/MPMI-03-12-0065-R,,wknogge@ipb-halle.de,no comments,S Kirsten,2012,,Kirsten-2012-Necrosis-inducing pr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3350,PHI:2699,UniProt,Q8PPR7,GenBank,AAM35507,,,306,HrpM,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Eureka,,,leaf,synthesis of a cyclic glucan,,,,loss of pathogenicity,,,,,,,,reduced,,no,hydrogen peroxide,CAS:7722-84-1,,,,,gene mutation: characterised; gene complementation,,,RP,22738424,PubMed,10.1111/j.1364-3703.2012.00809.x,,avojnov@fundacioncassara.org.ar,Decreased resistance to H2O2 in comparison with the wild-type strain,F Malamud,2012,1 gene,Malamud-2012-HrpM is involved in,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3351,PHI:2699,UniProt,Q8PPR7,GenBank,AAM35507,,,306,HrpM,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Macfadyen,,,leaf,synthesis of a cyclic glucan,,,,loss of pathogenicity,,,,,,,,reduced,,no,hydrogen peroxide,CAS:7722-84-1,,,,,gene mutation: characterised; gene complementation,,,RP,22738424,PubMed,10.1111/j.1364-3703.2012.00809.x,,avojnov@fundacioncassara.org.ar,Decreased resistance to H2O2 in comparison with the wild-type strain,F Malamud,2012,,Malamud-2012-HrpM is involved in,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3352,PHI:2700,UniProt,J7MF98,GenBank,BAM42534,,,104-T,lac2,,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,laccase gene,,,,reduced virulence,,yes,yes,no,,wild type; aberrant,,wild type,wild type,no,,,,,,,gene disruption,,,RP,22934563,PubMed,10.1094/MPMI-05-12-0131-R,,ytakano@kais.kyoto-u.ac.jp,no comments,S Y Lin,2012,1 gene,Lin-2012-LAC2 encoding a secr,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3353,PHI:2701,UniProt,Q8PQN7,GenBank,AAM35178,,,306,avrXacE1,,,,,,,53413,Xanthomonas axonopodis,,pv. citri,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22435635,PubMed,10.1111/j.1364-3703.2012.00797.x,,ottado@ibr.gov.ar,no comments,G Dunger,2012,Multi genes,Dunger-2012-Analysis of three Xa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3354,PHI:2702,UniProt,Q8PHM7,GenBank,AAM38068,,,306,avrXacE2,,,,,,,53413,Xanthomonas axonopodis,,pv. citri,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22435635,PubMed,10.1111/j.1364-3703.2012.00797.x,,ottado@ibr.gov.ar,no comments,G Dunger,2012,,Dunger-2012-Analysis of three Xa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3355,PHI:2703,UniProt,Q8PI08,GenBank,AAM37935,,,306,xac3090,,,,,,,53413,Xanthomonas axonopodis,,pv. citri,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22435635,PubMed,10.1111/j.1364-3703.2012.00797.x,,ottado@ibr.gov.ar,no comments,G Dunger,2012,,Dunger-2012-Analysis of three Xa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3356,PHI:2701,UniProt,Q8PQN7,GenBank,AAM35178,,,306,avrXacE1,,,,,,PHI:2702,53413,Xanthomonas axonopodis,,pv. citri,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22435635,PubMed,10.1111/j.1364-3703.2012.00797.x,,ottado@ibr.gov.ar,no comments,G Dunger,2012,,Dunger-2012-Analysis of three Xa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3357,PHI:2702,UniProt,Q8PHM7,GenBank,AAM38068,,,306,avrXacE2,,,,,,PHI:2701,53413,Xanthomonas axonopodis,,pv. citri,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22435635,PubMed,10.1111/j.1364-3703.2012.00797.x,,ottado@ibr.gov.ar,no comments,G Dunger,2012,,Dunger-2012-Analysis of three Xa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3358,PHI:2704,UniProt,F6MFB4,GenBank,FGSG_12013,,,PH-1,Tri12,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,suggested to play a role in export of trichothecene mycotoxins produced by Fusarium spp.,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,22835271,PubMed,10.1094/MPMI-04-12-0081-R,,hckist@umn.edu,no comments,J Menke,2012,1 gene,Menke-2012-Fusarium graminearum,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3359,PHI:2705,UniProt,C9Z5Q5,GenBank,CBG72886,,,87.22,EsxA,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Chippewa,,,tuber,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,Multi genes,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3360,PHI:2706,UniProt,C9Z5Q6,GenBank,CBG72887,,,87.22,EsxB,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Chippewa,,,tuber,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3361,PHI:2707,UniProt,C9Z5Q1,GenBank,CBG72882,,,87.22,EccC,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Chippewa,,,tuber,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,increased,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3362,PHI:2708,UniProt,C9Z5Q3,GenBank,CBG72884,,,87.22,EccD,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Chippewa,,,tuber,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3363,PHI:2705,UniProt,C9Z5Q5,GenBank,CBG72886,,,87.22,EsxA,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,seedling,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3364,PHI:2706,UniProt,C9Z5Q6,GenBank,CBG72887,,,87.22,EsxB,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,seedling,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3365,PHI:2707,UniProt,C9Z5Q1,GenBank,CBG72882,,,87.22,EccC,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,seedling,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,increased,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3366,PHI:2708,UniProt,C9Z5Q3,GenBank,CBG72884,,,87.22,EccD,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,seedling,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3367,PHI:2705,UniProt,C9Z5Q5,GenBank,CBG72886,,,87.22,EsxA,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,3726,Raphanus sativus (related: radish),,,,tuber,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3368,PHI:2706,UniProt,C9Z5Q6,GenBank,CBG72887,,,87.22,EsxB,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,3726,Raphanus sativus (related: radish),,,,tuber,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3369,PHI:2707,UniProt,C9Z5Q1,GenBank,CBG72882,,,87.22,EccC,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,3726,Raphanus sativus (related: radish),,,,tuber,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,increased,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3370,PHI:2708,UniProt,C9Z5Q3,GenBank,CBG72884,,,87.22,EccD,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,3726,Raphanus sativus (related: radish),,,,tuber,ESX/type VII secretion system,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23009676,PubMed,10.1111/j.1364-3703.2012.00835.x,,t.palmer@dundee.ac.u,Pathogen species formerly called Streptomyces scabies,J K Fyans,2013,,Fyans-2013-The ESX_type VII sec,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3371,PHI:2709,,no data found,GenBank,GH270297,,,,AMET,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,anthracnose,flowering plants,3435,Persea americana (related: avocado),cv. Fuerte,,,fruit,ammonium transporters,,,,reduced virulence,,no,,,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,23387470,PubMed,10.1094/MPMI-07-12-0170-R,,dovprusk@agri.gov.il,no comments,C Shnaiderman,2013,2 genes,Shnaiderman-2013-Differential Activat,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3372,PHI:2710,UniProt,H8ZZ79,GenBank,AFC37778,,,Cg-14,mepB,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,anthracnose,flowering plants,3435,Persea americana (related: avocado),cv. Fuerte,,,fruit,ammonium transporters,,,cAMP pathway,reduced virulence,,yes,,,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,23387470,PubMed,10.1094/MPMI-07-12-0170-R,,dovprusk@agri.gov.il,no comments,C Shnaiderman,2013,,Shnaiderman-2013-Differential Activat,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3373,PHI:2711,UniProt,G2X3W4,GenBank,EGY23263,,,VdLs.17,NLP1,chromosome 3,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling,necrosis and ethylene inducing like protein,,,,reduced virulence,,,,,,reduced,,wild type; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,23051172,PubMed,10.1094/MPMI-09-12-0222-R,,bart.thomma@wur.nl,no comments,P Santhanam,2013,2 genes,Santhanam-2013-Evidence for Functio,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3374,PHI:2712,UniProt,G2WWK9,GenBank,EGY19979,,,VdLs.17,NLP2,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling,necrosis and ethylene inducing like protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,23051172,PubMed,10.1094/MPMI-09-12-0222-R,,bart.thomma@wur.nl,no comments,P Santhanam,2013,,Santhanam-2013-Evidence for Functio,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3375,PHI:2711,UniProt,G2X3W4,GenBank,EGY23263,,,VdLs.17,NLP1,chromosome 3,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,necrosis and ethylene inducing like protein,,,,reduced virulence,,,,,,reduced,,wild type; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,23051172,PubMed,10.1094/MPMI-09-12-0222-R,,bart.thomma@wur.nl,no comments,P Santhanam,2013,,Santhanam-2013-Evidence for Functio,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3376,PHI:2712,UniProt,G2WWK9,GenBank,EGY19979,,,VdLs.17,NLP2,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,necrosis and ethylene inducing like protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,23051172,PubMed,10.1094/MPMI-09-12-0222-R,,bart.thomma@wur.nl,no comments,P Santhanam,2013,,Santhanam-2013-Evidence for Functio,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3377,PHI:2711,UniProt,G2X3W4,GenBank,EGY23263,,,VdLs.17,NLP1,chromosome 3,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,necrosis and ethylene inducing like protein,,,,reduced virulence,,,,,,reduced,,wild type; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,23051172,PubMed,10.1094/MPMI-09-12-0222-R,,bart.thomma@wur.nl,no comments,P Santhanam,2013,,Santhanam-2013-Evidence for Functio,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3378,PHI:2712,UniProt,G2WWK9,GenBank,EGY19979,,,VdLs.17,NLP2,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,necrosis and ethylene inducing like protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,23051172,PubMed,10.1094/MPMI-09-12-0222-R,,bart.thomma@wur.nl,no comments,P Santhanam,2013,,Santhanam-2013-Evidence for Functio,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3379,PHI:2713,UniProt,E1AYJ2,GenBank,ADM80412,,,CFBP1851,TALE1,,,,,,,53413,Xanthomonas axonopodis,1189617,pv. manihotis strain CFBP1851,bacterial blight (cassava),eudicots,3983,Manihot esculenta (related: cassava),cv. HMC-1,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,22947214,PubMed,10.1111/j.1364-3703.2012.00830.x,,abernal@uniandes.edu.co,no comments,L F Castiblanco,2013,1 gene,Castiblanco-2013-TALE1 from Xanthomon,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3380,PHI:2714,UniProt,I1RC71,GenBank,FGSG_01174.3,,,PH-1,PEX5,,,,,,,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,peroxisomal targeting signal receptor,,,,reduced virulence,yes,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22913493,PubMed,10.1094/MPMI-06-12-0149-R,,lee2443@snu.ac.kr,no comments,K Min,2012,Multi genes,Min-2012-Peroxisome function,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3381,PHI:2715,UniProt,A0A098DMW0,EMBL,FGRAMPH1_01T14959,,,PH-1,PEX6,,,,,,,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,peroxisomal biogenesis factor 6,,,,reduced virulence,yes,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22913493,PubMed,10.1094/MPMI-06-12-0149-R,,lee2443@snu.ac.kr,no comments,K Min,2012,,Min-2012-Peroxisome function,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3382,PHI:2716,UniProt,A0A0E0SHK9,EMBL,FGRAMPH1_01T17121,,,PH-1,PEX7,,,,,,,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,peroxin (PEX) protein,,,,unaffected pathogenicity,no,,,,,,wild type,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,22913493,PubMed,10.1094/MPMI-06-12-0149-R,,lee2443@snu.ac.kr,no comments,K Min,2012,,Min-2012-Peroxisome function,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3383,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,Multi genes,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3384,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3385,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3386,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3387,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3388,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3389,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3390,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3391,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3392,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3393,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3394,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3395,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3396,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3397,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3398,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3399,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3400,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3401,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3402,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3403,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3404,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3405,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3406,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3407,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3408,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3409,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3410,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3411,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3412,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3413,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3414,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3415,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3416,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3417,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3418,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3419,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3420,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3421,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3422,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3423,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3424,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3425,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3426,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3427,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3428,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3429,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3430,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3431,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3432,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3433,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3434,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3435,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3436,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3437,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3438,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3439,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3440,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3441,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3442,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3443,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3444,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3445,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3446,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3447,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3448,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3449,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3450,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3451,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3452,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3453,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3454,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3455,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3456,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3457,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3458,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3459,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3460,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3461,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3462,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3463,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3464,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3465,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3466,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3467,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3468,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3469,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3470,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3471,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3472,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3473,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3474,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3475,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3476,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3477,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3478,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3479,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3480,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3481,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3482,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3483,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3484,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3485,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3486,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3487,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3488,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3489,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3490,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3491,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3492,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3493,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3494,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3495,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3496,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3497,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3498,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3499,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3500,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3501,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3502,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3503,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3504,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3505,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3506,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3507,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3508,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3509,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3510,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3511,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3512,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3513,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3514,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3515,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3516,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3517,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3518,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3519,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3520,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3521,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3522,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3523,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3524,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3525,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3526,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Tainung 67,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3527,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3528,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3529,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3530,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3531,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3532,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3533,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3534,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3535,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3536,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3537,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3538,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dom Sufid,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3539,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3540,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3541,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3542,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3543,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3544,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3545,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3546,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3547,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3548,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3549,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3550,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Moroberecan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3551,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3552,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3553,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3554,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3555,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3556,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Cypress,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3557,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3558,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3559,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3560,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3561,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3562,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3563,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3564,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3565,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3566,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3567,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3568,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Sadu-cho,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3569,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3570,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3571,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3572,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3573,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3574,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3575,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3576,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3577,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3578,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3579,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3580,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. SHZ2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3581,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3582,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3583,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3584,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3585,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3586,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. IR64-21,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3587,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3588,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3589,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3590,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3591,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3592,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Swarna,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3593,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3594,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3595,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3596,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3597,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3598,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Pokkali,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3599,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3600,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3601,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3602,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3603,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3604,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),Ashwina landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3605,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3606,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3607,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3608,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3609,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3610,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Zhenshan 97B,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3611,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3612,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3613,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3614,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3615,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3616,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. N 22,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3617,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3618,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3619,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3620,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3621,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3622,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Dular,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3623,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3624,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3625,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3626,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3627,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3628,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),rayada group,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3629,PHI:2717,UniProt,Q9FDG1,GenBank,AF275317_1,,,PXO86,avrXa7,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3630,PHI:2718,UniProt,B2SU53,GenBank,AAS46025,,,PXO99,pthXo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3631,PHI:2719,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3632,PHI:2720,UniProt,G7T9N6,GenBank,AEQ94695,,,BLS256,tal1c,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3633,PHI:2721,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3634,PHI:2722,UniProt,G7TJZ8,GenBank,AEQ95741,,,BLS256,tal2g,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. FR13A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23078195,PubMed,10.1111/j.1469-8137.2012.04367.x,,jan.leach@colostate.edu,no comments,V Verdier,2012,,Verdier-2012-Transcription activa,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3635,PHI:2723,,no data found,GenBank,BC1G_02386.1,,,,Bcgar1,,,,,,PHI:2724,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,galacturonate reductase genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,Multi genes,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3636,PHI:2724,,no data found,GenBank,BC1G_02027.1,,,,Bcgar2,,,,,,PHI:2723,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,galacturonate reductase genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3637,PHI:2725,,no data found,GenBank,BC1G_08318.1,,,,Bclgd1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,galactonate dehydratase gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3638,PHI:2726,,no data found,GenBank,BC1G_02028.1,,,,Bclga1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,2-keto-3-deoxy-L-galactonate aldolase gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3639,PHI:2723,,no data found,GenBank,BC1G_02386.1,,,,Bcgar1,,,,,,PHI:2724,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,galacturonate reductase genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3640,PHI:2724,,no data found,GenBank,BC1G_02027.1,,,,Bcgar2,,,,,,PHI:2723,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,galacturonate reductase genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3641,PHI:2725,,no data found,GenBank,BC1G_08318.1,,,,Bclgd1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,galactonate dehydratase gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3642,PHI:2726,,no data found,GenBank,BC1G_02028.1,,,,Bclga1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,2-keto-3-deoxy-L-galactonate aldolase gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3643,PHI:2723,,no data found,GenBank,BC1G_02386.1,,,,Bcgar1,,,,,,PHI:2724,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,galacturonate reductase genes,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3644,PHI:2724,,no data found,GenBank,BC1G_02027.1,,,,Bcgar2,,,,,,PHI:2723,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,galacturonate reductase genes,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3645,PHI:2725,,no data found,GenBank,BC1G_08318.1,,,,Bclgd1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,galactonate dehydratase gene,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3646,PHI:2726,,no data found,GenBank,BC1G_02028.1,,,,Bclga1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,2-keto-3-deoxy-L-galactonate aldolase gene,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22937823,PubMed,10.1111/j.1364-3703.2012.00825.x,,jan.vankan@wur.nl,no comments,L Zhang,2013,,Zhang-2013-Botrytis cinerea mut,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3647,PHI:2727,UniProt,E0W4Y2,GenBank,AEK81007,,,P7064,Avh241,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,RxLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,cell death,altered gene expression / gene regulation: overexpression,,,RP,22816601,PubMed,10.1111/j.1469-8137.2012.04241.x,,wangyc@njau.edu.cn,A. tumefaciens strain GV3101,X Yu,2012,1 gene,Yu-2012-The RxLR effector Av,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3648,PHI:2727,UniProt,E0W4Y2,GenBank,AEK81007,,,P7064,Avh241,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,RxLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,cell death,altered gene expression / gene regulation: silencing,,,RP,22816601,PubMed,10.1111/j.1469-8137.2012.04241.x,,wangyc@njau.edu.cn,A. tumefaciens strain GV3101,X Yu,2012,,Yu-2012-The RxLR effector Av,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3649,PHI:2728,UniProt,I1RZZ3,Broad,FGSG_10003.3,,,,FgERG4,,,,,,,5518,Fusarium graminearum,,HN9-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,sterol C-24 reductase,,,ergosterol biosynthesis pathway,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,"copper, ion (cu2+); magnesium cation; calcium cation; iron, ion (fe3+); aluminium, ion (al3+); sodium chloride; sorbitol; hydrogen peroxide; paraquat; triadimefon; tebuconazole; tridemorph; fenpropidin; spiroxamine; nystatin; amphotericin B; cellulase; muramidase [lysozyme]; snailase","copper,  ion (cu2+): CAS:15158-11-9; magnesium cation: CAS:22537-22-0; calcium cation: CAS:14127-61-8; iron,  ion (fe3+): CAS:20074-52-6; aluminium,  ion (al3+): CAS:22537-23-1; sodium chloride: CAS:7647-14-5; sorbitol: CAS:50-70-4; hydrogen peroxide: CAS:7722-84-1; paraquat: CAS:4685-14-7; triadimefon: CAS:43121-43-3; tebuconazole: CAS:107534-96-3; tridemorph: CHEBI:9700, CAS:24602-86-6; fenpropidin: CHEBI:81917, CAS:67306-00-7; spiroxamine: CHEBI:9242, CAS:118134-30-8; nystatin: CAS:1400-61-9; amphotericin B: CAS:1397-89-3; cellulase: CAS:9012-54-8; muramidase: CAS:9001-63-2; snailase: CAS:39450-01-6",,,,,gene disruption; gene complementation,,,RP,22947191,PubMed,10.1111/j.1364-3703.2012.00829.x,,zhma@zju.edu.cn,The mutant showed increased sensitivity to metal cations and to various cell stresses. Mycelia of Delta FgErg4-2 revealed increased resistance to cell wall-degrading enzymes. Fungicide sensitivity tests revealed that DFgErg4-2 showed increased resist-ance to various sterol biosynthesis inhibitors (SBIs).,X Liu,2013,1 gene,Liu-2013-Involvement of FgERG,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3650,PHI:2728,UniProt,I1RZZ3,Broad,FGSG_10003.3,,,,FgERG4,,,,,,,5518,Fusarium graminearum,,HN9-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,sterol C-24 reductase,,,ergosterol biosynthesis pathway,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,"copper, ion (cu2+); magnesium cation; calcium cation; iron, ion (fe3+); aluminium, ion (al3+); sodium chloride; sorbitol; hydrogen peroxide; paraquat; triadimefon; tebuconazole; tridemorph; fenpropidin; spiroxamine; nystatin; amphotericin B; cellulase; muramidase [lysozyme]; snailase","copper,  ion (cu2+): CAS:15158-11-9; magnesium cation: CAS:22537-22-0; calcium cation: CAS:14127-61-8; iron,  ion (fe3+): CAS:20074-52-6; aluminium,  ion (al3+): CAS:22537-23-1; sodium chloride: CAS:7647-14-5; sorbitol: CAS:50-70-4; hydrogen peroxide: CAS:7722-84-1; paraquat: CAS:4685-14-7; triadimefon: CAS:43121-43-3; tebuconazole: CAS:107534-96-3; tridemorph: CHEBI:9700, CAS:24602-86-6; fenpropidin: CHEBI:81917, CAS:67306-00-7; spiroxamine: CHEBI:9242, CAS:118134-30-8; nystatin: CAS:1400-61-9; amphotericin B: CAS:1397-89-3; cellulase: CAS:9012-54-8; muramidase: CAS:9001-63-2; snailase: CAS:39450-01-6",,,,,gene disruption; gene complementation,,,RP,22947191,PubMed,10.1111/j.1364-3703.2012.00829.x,,zhma@zju.edu.cn,The mutant showed increased sensitivity to metal cations and to various cell stresses. Mycelia of Delta FgErg4-2 revealed increased resistance to cell wall-degrading enzymes. Fungicide sensitivity tests revealed that DFgErg4-2 showed increased resist-ance to various sterol biosynthesis inhibitors (SBIs).,X Liu,2013,,Liu-2013-Involvement of FgERG,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3651,PHI:2729,UniProt,B2SME5,GenBank,ACD59145,,,PXO99A,PdeK,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,two-component system PdeK/PdeR regulates c-di-GMP turnover,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,22712508,PubMed,10.1094/MPMI-01-12-0014-R,,cyhe@caas.net.cn,no comments,F Yang,2012,2 genes,Yang-2012-A novel two-componen,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3652,PHI:2730,UniProt,B2SME4,GenBank,ACD59144,,,PXO99A,PdeR,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,two-component system PdeK/PdeR regulates c-di-GMP turnover,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,22712508,PubMed,10.1094/MPMI-01-12-0014-R,,cyhe@caas.net.cn,no comments,F Yang,2012,,Yang-2012-A novel two-componen,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3653,PHI:2731,UniProt,G2XD29,GenBank,EGY16897,,,VdLs.17,VdSge1,chromosome 6,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,transcriptional regulator,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,22970788,PubMed,10.1094/MPMI-08-12-0198-R,,bart.thomma@wur.nl,no comments,P Santhanam,2013,1 gene,Santhanam-2013-Verticillium dahliae,Batch024,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3654,PHI:2732,UniProt,Q97T11,GenBank,AAK74331,,,TIGR4,metQ,,,,,,,1313,Streptococcus pneumoniae,,100993,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,bronchoalveolar lavage fluid; lung; spleen,methionine ABC transporter lipoprotein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,23349662,PubMed,10.1371/journal.pone.0049638,,jeremy.brown@ucl.ac.uk,no comments,S Basavanna,2013,3 genes,Free access from PubMed,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3655,PHI:2733,UniProt,Q97S31,GenBank,AAK74738,,,TIGR4,metE,,,,,,PHI:2734,1313,Streptococcus pneumoniae,,100993,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,bronchoalveolar lavage fluid; lung; spleen,methionine biosynthesis enzymes,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,23349662,PubMed,10.1371/journal.pone.0049638,,jeremy.brown@ucl.ac.uk,no comments,S Basavanna,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3656,PHI:2734,UniProt,Q97S30,GenBank,AAK74739,,,TIGR4,metF,,,,,,PHI:2733,1313,Streptococcus pneumoniae,,100993,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,bronchoalveolar lavage fluid; lung; spleen,methionine biosynthesis enzymes,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,23349662,PubMed,10.1371/journal.pone.0049638,,jeremy.brown@ucl.ac.uk,no comments,S Basavanna,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3657,PHI:2732,UniProt,Q97T11,GenBank,AAK74331,,,TIGR4,metQ,,,,,,PHI:2733; PHI:2734,1313,Streptococcus pneumoniae,,100993,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,bronchoalveolar lavage fluid; lung; spleen,methionine ABC transporter lipoprotein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,23349662,PubMed,10.1371/journal.pone.0049638,,jeremy.brown@ucl.ac.uk,no comments,S Basavanna,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3658,PHI:2733,UniProt,Q97S31,GenBank,AAK74738,,,TIGR4,metE,,,,,,PHI:2734; PHI:2732,1313,Streptococcus pneumoniae,,100993,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,bronchoalveolar lavage fluid; lung; spleen,methionine biosynthesis enzymes,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,23349662,PubMed,10.1371/journal.pone.0049638,,jeremy.brown@ucl.ac.uk,no comments,S Basavanna,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3659,PHI:2734,UniProt,Q97S30,GenBank,AAK74739,,,TIGR4,metF,,,,,,PHI:2733; PHI:2732,1313,Streptococcus pneumoniae,,100993,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,bronchoalveolar lavage fluid; lung; spleen,methionine biosynthesis enzymes,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,23349662,PubMed,10.1371/journal.pone.0049638,,jeremy.brown@ucl.ac.uk,no comments,S Basavanna,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3660,PHI:2735,UniProt,D0KML5,GenBank,ACX89566,,,WPP163,RsmA,,,,,,,55208,Pectobacterium wasabiae,,SCC3193,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Ants,,,tuber,posttranscriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,,,,,,,gene disruption,,,RP,23372695,PubMed,10.1371/journal.pone.0054248,,pontu55@hot.ee,no comments,V Koiv,2013,1 gene,Free access from PubMed,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3661,PHI:2735,UniProt,D0KML5,GenBank,ACX89566,,,WPP163,RsmA,,,,,,,55208,Pectobacterium wasabiae,,SCC3193,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,seedling,posttranscriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,,,,,,,gene disruption,,,RP,23372695,PubMed,10.1371/journal.pone.0054248,,pontu55@hot.ee,no comments,V Koiv,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3662,PHI:2736,UniProt,Q97PH9,GenBank,AAK75718,,,TIGR4,IDTR,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; nasal cavity,putative iron-dependent transcriptional regulator,,,,reduced virulence,,,,,,,,wild type; aberrant,,no,,,,,,,gene deletion: full,,,RP,23437050,PubMed,10.1371/journal.pone.0055157,,eswiatlo@ umc.edu,no comments,R Gupta,2013,1 gene,Free access from PubMed,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3663,PHI:2737,UniProt,Q5H2X8,GenBank,AAW74693,,,KACC 10331,SSBX,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica,,,leaf,single-stranded DNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23418541,PubMed,10.1371/journal.pone.0056240,,gyouchen@sjtu.edu.cn,no comments,Y Li,2013,2 genes,Free access from PubMed,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3664,PHI:2738,UniProt,B2SVR3,GenBank,ACD56757,,,PXO99A,hpa1,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica,,,leaf,hairpin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23418541,PubMed,10.1371/journal.pone.0056240,,gyouchen@sjtu.edu.cn,no comments,Y Li,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3665,PHI:2738,UniProt,B2SVR3,GenBank,ACD56757,,,PXO99A,hpa1,,,,,,PHI:2737,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica,,,leaf,hairpin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23418541,PubMed,10.1371/journal.pone.0056240,,gyouchen@sjtu.edu.cn,no comments,Y Li,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3666,PHI:2737,UniProt,Q5H2X8,GenBank,AAW74693,,,KACC 10331,SSBX,,,,,,PHI:2738,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica,,,leaf,single-stranded DNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23418541,PubMed,10.1371/journal.pone.0056240,,gyouchen@sjtu.edu.cn,no comments,Y Li,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3667,PHI:2739,UniProt,Q8E0Q7,GenBank,AE014221_14,,,2603V/R,cylE,,,,,,,1311,Streptococcus agalactiae,,group B serotype V strain CNCTC 10/84,pneumonia; meningitis; sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bladder; kidney,toxin b-hemolysin/cytolysin production,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23505569,PubMed,10.1371/journal.pone.0059091,,ar127@columbia. edu,no comments,R Kulkarni,2013,1 gene,Free access from PubMed,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3668,PHI:2740,UniProt,P9WJV2,GenBank,AAK44689,,,CDC1551,MmpL4,,,,,,PHI:2741,1773,Mycobacterium tuberculosis,,ML617,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,iron-regulated genes encoding predicted outer membrane proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23431276,PubMed,10.1371/journal.ppat.1003120,,mnieder@uab.edu,no comments,R M Wells,2013,2 genes,Free access from PubMed,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3669,PHI:2741,UniProt,P9WJV0,GenBank,AAK44930,,,CDC1551,MmpL5,,,,,,PHI:2740,1773,Mycobacterium tuberculosis,,ML617,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,iron-regulated genes encoding predicted outer membrane proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23431276,PubMed,10.1371/journal.ppat.1003120,,mnieder@uab.edu,no comments,R M Wells,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3670,PHI:2742,UniProt,Q08242,GenBank,AAA25728,,,,avrPto,,,,,,,317,Pseudomonas syringae,,,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23382672,PubMed,10.1371/journal.ppat.1003123,,john.rathjen@anu. edu.au,A. tumefaciens strain C58C1,V Ntoukakis,2013,2 genes,Free access from PubMed,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3671,PHI:2743,UniProt,Q8RSY1,GenBank,AAL71883,,,DC3000,avrPtoB,,,,,,,317,Pseudomonas syringae,,,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23382672,PubMed,10.1371/journal.ppat.1003123,,john.rathjen@anu. edu.au,A. tumefaciens strain C58C1,V Ntoukakis,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3672,PHI:2742,UniProt,Q08242,GenBank,AAA25728,,,,avrPto,,,,,,,317,Pseudomonas syringae,,,bacterial speck,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23382672,PubMed,10.1371/journal.ppat.1003123,,john.rathjen@anu. edu.au,A. tumefaciens strain C58C1,V Ntoukakis,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3673,PHI:2743,UniProt,Q8RSY1,GenBank,AAL71883,,,DC3000,avrPtoB,,,,,,,317,Pseudomonas syringae,,,bacterial speck,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23382672,PubMed,10.1371/journal.ppat.1003123,,john.rathjen@anu. edu.au,A. tumefaciens strain C58C1,V Ntoukakis,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3674,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878,,,521,Pit2 (um01375),chromosome 2,SG200deltapit2-pit2,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,wild type pit2 fully restored disease tumor formation of the pit2 deletion mutant,gene deletion; gene complementation,,,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,Pit2 transformed into Pit2 deletion mutant,Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3675,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878,,,521,Pit2 (um01375),chromosome 2,SG200deltapit2-pit2delta44-57,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,mutant pit2 was unable to restore tumor formation of the pit2 deletion mutant,gene deletion; gene mutation: characterised,,,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,pit2delta44-57 transformed into Pit2 deletion mutant,Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3676,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878,,,521,Pit2 (um01375),chromosome 2,SG200deltapit2-pit2mut49-53,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,mutant pit2 was unable to restore tumor formation of the pit2 deletion mutant,gene deletion; gene mutation: characterised,,,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,pit2mut49-53 transformed into Pit2 deletion mutant,Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3677,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878; Ensembl: UMAG01375,,,521,Pit2 (um01375),chromosome 2,pGBKT7-pit2delta44-57,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize) (non-host bioassay: yeast),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,"pGADT7-CP2 (w/o N-terminal prodomain, w/o N-terminal SP)",UniProt: Q43705; GenBank: NP_001105479; Ensembl: GRMZM2G038636,marginal growth in yeast two-hybrid,,other evidence: yeast two-hybrid,,,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,"Pit2 inhibits maize cysteine proteases (including CP2 (corn cysteine protease 2, synonyms: See1, ccp2))",Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3678,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878; Ensembl: UMAG01375,,,521,Pit2 (um01375),chromosome 2,pGBKT7-pit2delta49-53,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize) (non-host bioassay: yeast),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,"pGADT7-CP2 (w/o N-terminal prodomain, w/o N-terminal SP)",UniProt: Q43705; GenBank: NP_001105479; Ensembl: GRMZM2G038636,interacts in yeast two-hybrid (almost same as pit2 wildtype CP2 Y2H),,other evidence: yeast two-hybrid,,,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,"Pit2 inhibits maize cysteine proteases (including CP2 (corn cysteine protease 2, synonyms: See1, ccp2))",Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3679,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878; Ensembl: UMAG01375,,,521,Pit2 (um01375),chromosome 2,pGBKT7-pit2mut49-53,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize) (non-host bioassay: yeast),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,"pGADT7-CP2 (w/o N-terminal prodomain, w/o N-terminal SP)",UniProt: Q43705; GenBank: NP_001105479; Ensembl: GRMZM2G038636,interacts in yeast two-hybrid (almost same as pit2 wildtype CP2 Y2H),,other evidence: yeast two-hybrid,,,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,"Pit2 inhibits maize cysteine proteases (including CP2 (corn cysteine protease 2, synonyms: See1, ccp2))",Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3680,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878; Ensembl: UMAG01375,,,521,Pit2 (um01375),chromosome 2,pGBKT7-Pit2 (without N-terminal secretion signal),,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize) (non-host bioassay: yeast),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,"pGADT7-CP2 full (full-length protease including N-terminal prodomain, w/o N-terminal SP)",UniProt: Q43705; GenBank: NP_001105479; Ensembl: GRMZM2G038636,no interaction in yeast two-hybrid,,other evidence: yeast two-hybrid,,,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,"Pit2 inhibits maize cysteine proteases (including CP2 (corn cysteine protease 2, synonyms: See1, ccp2))",Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3681,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878; Ensembl: UMAG01375,,,521,Pit2 (um01375),chromosome 2,pGBKT7-Pit2 (without N-terminal secretion signal),,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize) (non-host bioassay: yeast),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,"pGADT7-CP2 (w/o N-terminal prodomain, w/o N-terminal SP)",UniProt: Q43705; GenBank: NP_001105479; Ensembl: GRMZM2G038636,interacts in yeast two-hybrid,,other evidence: yeast two-hybrid,,,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,"Pit2 inhibits maize cysteine proteases (including CP2 (corn cysteine protease 2, synonyms: See1, ccp2))",Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3682,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878; Ensembl: UMAG01375,,,521,Pit2 (um01375),chromosome 2,pGBKT7-Pit2 (without N-terminal secretion signal),,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize) (non-host bioassay: yeast),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,"pGADT7-CP2i (w/o N-terminal prodomain, w/o N-terminal SP and mutations in C167, H307 and A327)",UniProt: Q43705; GenBank: NP_001105479; Ensembl: GRMZM2G038636,interacts in yeast two-hybrid,,other evidence: yeast two-hybrid,,,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,"Pit2 inhibits maize cysteine proteases (including CP2 (corn cysteine protease 2, synonyms: See1, ccp2)) point mutations were made in the CP2 catalytic triad residues Cys167, His307, Asn327.",Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3683,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878; Ensembl: UMAG01375,,,521,Pit2 (um01375),chromosome 2,pGBKT7-Pit2 (without N-terminal secretion signal),,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize) (non-host bioassay: yeast),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,"pGADT7-CP2 (w/o N-terminal prodomain, w/o N-terminal SP)",UniProt: Q43705; GenBank: NP_001105479; Ensembl: GRMZM2G038636,interaction (positive co-IP),,"heterologous expression; other evidence: expression in yeast, followed by co-ip",,,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,"Pit2 inhibits maize cysteine proteases (including CP2 (corn cysteine protease 2, synonyms: See1, ccp2)). Co-IP with total protein extract of yeast cells expressing both proteins. Using anti-HA matrix, Pit2-MYC was co-IP by the HA-tagged CP2 but not by HA-tagged activation domain (negative control).",Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3684,PHI:2744,UniProt,Q4PET8,GenBank,EAK81878; Ensembl: UMAG01375,,,521,Pit2 (um01375),chromosome 2,E. coli expressed GST-Pit2,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize) (non-host bioassay: nicotiana benthamiana),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,CP2-HA expressed in Nb,UniProt: Q43705; GenBank: NP_001105479; Ensembl: GRMZM2G038636,interaction (positive co-IP),,functional test in host: transient expression,"Agrobacterium-mediated co-expression by infiltration, followed by co-IP",,AC,23459172,PubMed,10.1371/journal.ppat.1003177,PLoS Pathog.2013 Feb;9(2):e1003177,doehlemann@mpi-marburg.mpg.de,"Pit2 inhibits maize cysteine proteases (including CP2 (corn cysteine protease 2, synonyms: See1, ccp2)). Positive Co-IP of E. coli expressed GST-Pit2 and CP2-HA expressed in Nb.",Mueller et al.,2013,,,AC First Host Target Curation update,2016-01-18,RRes,,,,,,,,,,,,,
,,Record 3685,PHI:2745,UniProt,Q02LV5,GenBank,ABJ15692,,,UCBPP-PA14,treY,,,,,,PHI:2746,287,Pseudomonas aeruginosa,652611,PA14,soft rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,trehalose biosynthetic genes,,,,reduced virulence,,,,,,,,,,no,trehalose; ammonium nitrate,trehalose: CAS:99-20-7; ammonium nitrate: CAS:6484-52-2,,,,,gene disruption,,,RP,23505373,PubMed,10.1371/journal.ppat.1003217,,ausubel@molbio.mgh.harvard.edu,"Exogenously co-inoculated trehalose, ammonium, or nitrate, but not glucose, sulfate, or phosphate suppressed the phenotype of the double delta treYZ delta treS mutants.",S Djonovic,2013,2 genes,Free access from PubMed,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3686,PHI:2746,UniProt,Q02LV7,GenBank,ABJ11342,,,UCBPP-PA14,treZ,,,,,,PHI:2745,287,Pseudomonas aeruginosa,652611,PA14,soft rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,trehalose biosynthetic genes,,,,reduced virulence,,,,,,,,,,no,trehalose; ammonium nitrate,trehalose: CAS:99-20-7; ammonium nitrate: CAS:6484-52-2,,,,,gene disruption,,,RP,23505373,PubMed,10.1371/journal.ppat.1003217,,ausubel@molbio.mgh.harvard.edu,"Exogenously co-inoculated trehalose, ammonium, or nitrate, but not glucose, sulfate, or phosphate suppressed the phenotype of the double delta treYZ delta treS mutants.",S Djonovic,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3687,PHI:2745,UniProt,Q02LV5,GenBank,ABJ15692,,,UCBPP-PA14,treY,,,,,,PHI:2746,287,Pseudomonas aeruginosa,652611,PA14,soft rot,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,trehalose biosynthetic genes,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23505373,PubMed,10.1371/journal.ppat.1003217,,ausubel@molbio.mgh.harvard.edu,no comments,S Djonovic,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3688,PHI:2746,UniProt,Q02LV7,GenBank,ABJ11342,,,UCBPP-PA14,treZ,,,,,,PHI:2745,287,Pseudomonas aeruginosa,652611,PA14,soft rot,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,trehalose biosynthetic genes,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23505373,PubMed,10.1371/journal.ppat.1003217,,ausubel@molbio.mgh.harvard.edu,no comments,S Djonovic,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3689,PHI:2745,UniProt,Q02LV5,GenBank,ABJ15692,,,UCBPP-PA14,treY,,,,,,PHI:2746,287,Pseudomonas aeruginosa,652611,PA14,soft rot,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,lung; spleen,trehalose biosynthetic genes,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23505373,PubMed,10.1371/journal.ppat.1003217,,ausubel@molbio.mgh.harvard.edu,no comments,S Djonovic,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3690,PHI:2746,UniProt,Q02LV7,GenBank,ABJ11342,,,UCBPP-PA14,treZ,,,,,,PHI:2745,287,Pseudomonas aeruginosa,652611,PA14,soft rot,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,lung; spleen,trehalose biosynthetic genes,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23505373,PubMed,10.1371/journal.ppat.1003217,,ausubel@molbio.mgh.harvard.edu,no comments,S Djonovic,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3691,PHI:2745,UniProt,Q02LV5,GenBank,ABJ15692,,,UCBPP-PA14,treY,,,,,,PHI:2746,287,Pseudomonas aeruginosa,652611,PA14,soft rot,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,trehalose biosynthetic genes,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23505373,PubMed,10.1371/journal.ppat.1003217,,ausubel@molbio.mgh.harvard.edu,no comments,S Djonovic,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3692,PHI:2746,UniProt,Q02LV7,GenBank,ABJ11342,,,UCBPP-PA14,treZ,,,,,,PHI:2745,287,Pseudomonas aeruginosa,652611,PA14,soft rot,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,trehalose biosynthetic genes,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23505373,PubMed,10.1371/journal.ppat.1003217,,ausubel@molbio.mgh.harvard.edu,no comments,S Djonovic,2013,,,Batch025,2013-03-01,MC,,,,,,,,,,,,,
,,Record 3693,PHI:2747,UniProt,A8YZD7,GenBank,ABX28363,,,USA300_TCH1516,Cnt,,,,,,,1280,Staphylococcus aureus,,RN6390,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; kidney,cobalt and nickel transporter,,,,reduced virulence,,,,,,,,,,no,zinc; cobalt; nickel,zinc: CHEBI:37255; cobalt: CHEBI:23336; nickel: CHEBI:25516,,,,,gene deletion: full,,,RP,23279021,PubMed,10.1111/mmi.12126,,elise.borezee-durant@jouy.inra.fr,"Zinc specifically inhibits Cnt-mediated nickel and cobalt uptake, on both functional and transcriptional levels.",L Remy,2013,1 gene,Remy-2013-The Staphylococcus a,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3694,PHI:2748,,no data found,MUMDB,um11293,,,,snf1,,,,,,,5270,Ustilago maydis,237631,512,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Bantam,,,seedling,dual regulator of cell wall degrading enzymes,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,21062173,PubMed,10.1094/PHYTO-01-10-0011,,sgold@uga.edu,no comments,M Nadal,2010,1 gene,Nadal-2010-The snf1 gene of Ust,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3695,PHI:2749,UniProt,P0CS63,GenBank,EAL17830,,,B-3501A,Rim101,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,transcription factor that regulates cell wall composition and the host-pathogen interface,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,increased inflammatory response,gene deletion: full,,,RP,23322637,PubMed,10.1128/mBio.00522-12,,andrew.alspaugh@duke.edu,"Mice infected with the rim101 mutant strain showed significantly decreased fungal burdens, despite demon-strating death kinetics similar to those of mice infected with the WT strain; due to increased inflammatory response.",T R O'Meara,2013,1 gene,O'Meara-2013-Cryptococcus neoform,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3696,PHI:2749,UniProt,P0CS63,GenBank,EAL17830,,,B-3501A,Rim101,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung,transcription factor that regulates cell wall composition and the host-pathogen interface,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,increased inflammatory response,gene deletion: full,,,RP,23322637,PubMed,10.1128/mBio.00522-12,,andrew.alspaugh@duke.edu,"Mice infected with the rim101 mutant strain showed significantly decreased fungal burdens, despite demon-strating death kinetics similar to those of mice infected with the WT strain; due to increased inflammatory response.",T R O'Meara,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3697,PHI:2750,,no data found,,,,,,visP,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,periplasmic protein of the bacterial oligonucleotide/oligosaccharide-binding fold family,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23302685,PubMed,10.1073/pnas.1215416110,,vanessa.sperandio@utsouthwestern,no comments,C G Moreira,2013,2 genes,Moreira-2013-Virulence and stress,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3698,PHI:2751,UniProt,E1WEX6,GenBank,CBW20309,,,SL1344,lpxO,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,fe2+/alpha-ketoglutarate-dependent dioxygenase enzyme,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23302685,PubMed,10.1073/pnas.1215416110,,vanessa.sperandio@utsouthwestern,no comments,C G Moreira,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3699,PHI:2750,,no data found,,,,,,visP,,,,,,PHI:2751,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,periplasmic protein of the bacterial oligonucleotide/oligosaccharide-binding fold family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23302685,PubMed,10.1073/pnas.1215416110,,vanessa.sperandio@utsouthwestern,no comments,C G Moreira,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3700,PHI:2751,UniProt,E1WEX6,GenBank,CBW20309,,,SL1344,lpxO,,,,,,PHI:2750,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,fe2+/alpha-ketoglutarate-dependent dioxygenase enzyme,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23302685,PubMed,10.1073/pnas.1215416110,,vanessa.sperandio@utsouthwestern,no comments,C G Moreira,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3701,PHI:2752,UniProt,Q888Y7,GenBank,AAO54411,,,DC3000,HopQ1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,RP,23417089,PubMed,10.1104/pp.112.211748,,glcoaker@ucdavis.edu,Agrobacterium tumefaciens strain GV3101,W Li,2013,1 gene,Li-2013-The Pseudomonas effe,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3702,PHI:2753,,no data found,GenBank,C4_45679,,,,Llm1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-N,,,leaf,Lae1-like methyltransferase,,,,reduced virulence,yes,,,,,increased; aberrant,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23261970,PubMed,10.1016/j.fgb.2012.11.012,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,Q Bi,2013,1 gene,Bi-2013-Cochliobolus heteros,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3703,PHI:2753,,no data found,GenBank,C4_45679,,,,Llm1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-T,,,leaf,Lae1-like methyltransferase,,,,reduced virulence,yes,,,,,increased; aberrant,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23261970,PubMed,10.1016/j.fgb.2012.11.012,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,Q Bi,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3704,PHI:2753,,no data found,GenBank,C4_45679,,,,Llm1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-N,,,leaf,Lae1-like methyltransferase,,,,increased virulence (hypervirulence),no,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,RP,23261970,PubMed,10.1016/j.fgb.2012.11.012,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,Q Bi,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3705,PHI:2753,,no data found,GenBank,C4_45679,,,,Llm1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-T,,,leaf,Lae1-like methyltransferase,,,,increased virulence (hypervirulence),no,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,RP,23261970,PubMed,10.1016/j.fgb.2012.11.012,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,Q Bi,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3706,PHI:2754,UniProt,C5A9K2,GenBank,ACR27503,,,BGR1,T3SS,,,,,,,337,Burkholderia glumae,,106619,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Kanto 51,,,leaf,tool for translocating pathogen effectors to monocot cells,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23451734,PubMed,10.1111/tpj.12148,,saitoh@ibrc.or.jp,"T3SS of Burkholderia glumae, is used to translocate the AVR-Pik and AVR-Pii effectors of the fungal pathogen Magnaporthe oryzae to rice cytoplasm. The translocated AVR-Pik and AVR-Pii showed avirulence activity when tested in rice cultivars containing the cognate R genes.",S Sharma,2013,1 gene,Sharma-2013-Deployment of the Bu,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3707,PHI:2754,UniProt,C5A9K2,GenBank,ACR27503,,,BGR1,T3SS,,,,,,,337,Burkholderia glumae,,106619,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Moukoto,,,leaf,tool for translocating pathogen effectors to monocot cells,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23451734,PubMed,10.1111/tpj.12148,,saitoh@ibrc.or.jp,"T3SS of Burkholderia glumae, is used to translocate the AVR-Pik and AVR-Pii effectors of the fungal pathogen Magnaporthe oryzae to rice cytoplasm. The translocated AVR-Pik and AVR-Pii showed avirulence activity when tested in rice cultivars containing the cognate R genes.",S Sharma,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3708,PHI:2754,UniProt,C5A9K2,GenBank,ACR27503,,,BGR1,T3SS,,,,,,,337,Burkholderia glumae,,106619,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Kakehashi,,,leaf,tool for translocating pathogen effectors to monocot cells,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23451734,PubMed,10.1111/tpj.12148,,saitoh@ibrc.or.jp,"T3SS of Burkholderia glumae, is used to translocate the AVR-Pik and AVR-Pii effectors of the fungal pathogen Magnaporthe oryzae to rice cytoplasm. The translocated AVR-Pik and AVR-Pii showed avirulence activity when tested in rice cultivars containing the cognate R genes.",S Sharma,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3709,PHI:2755,UniProt,D7HXL1,ASAP,AER-0001621,,,NCPPB 3335,HP0598,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,Multi genes,Matas-2012-Identification of no,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3710,PHI:2756,UniProt,D7HZT3,ASAP,AER-0002425,,,NCPPB 3335,arsB,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,arsenical pump membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3711,PHI:2757,UniProt,D7I5K1,ASAP,AER-0004505,,,NCPPB 3335,cysT,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,sulfate transport system permease protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3712,PHI:2758,UniProt,D7I5I3,ASAP,AER-0004487,,,NCPPB 3335,spmAB,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,spore maturation protein AB,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3713,PHI:2759,UniProt,D7HTI1,ASAP,AER-0000128,,,NCPPB 3335,mltB,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,membrane-bound lytic murein transglycosylase B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3714,PHI:2760,UniProt,D7HZ13,ASAP,AER-0002142,,,NCPPB 3335,EEP,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,endonuclease/exonuclease/phosphatase family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3715,PHI:2761,,no data found,ASAP,AER-0000150,,,NCPPB 3335,thiE,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,thiamin-phosphate pyrophosphorylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3716,PHI:2762,UniProt,D7I4E7,ASAP,AER-0004088,,,NCPPB 3335,GGDEF,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,GGDEF domain/EAL domain protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3717,PHI:2763,UniProt,D7I1I0,ASAP,AER-0003040,,,NCPPB 3335,pqiB,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,paraquat-inducible protein B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3718,PHI:2764,UniProt,D7HUU4,ASAP,AER-0000607,,,NCPPB 3335,virB4,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,type IVA secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3719,PHI:2765,UniProt,D7I656,ASAP,AER-0004717,,,NCPPB 3335,gltP,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,proton/glutamate symporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3720,PHI:2766,UniProt,D7HUA3,ASAP,AER-000413,,,NCPPB 3335,catJ,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,3-oxoadipate CoA-transferase subunit B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3721,PHI:2767,UniProt,D7I589,ASAP,AER-0004392,,,NCPPB 3335,citN,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,citrate transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3722,PHI:2768,UniProt,D7I5R7,ASAP,AER-0004572,,,NCPPB 3335,algT,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,RNA polymerase sigma-22 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3723,PHI:2769,UniProt,D7HU30,ASAP,AER-0000339,,,NCPPB 3335,traY,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,type IVB secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3724,PHI:2770,UniProt,D7HVA7,ASAP,AER-0000777,,,NCPPB 3335,rubB,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,rubredoxin-NAD( +) reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3725,PHI:2771,UniProt,D7HX46,ASAP,AER-0001448,,,NCPPB 3335,secG,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,preprotein translocase subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3726,PHI:2772,UniProt,D7I5Z5,ASAP,AER-0004655,,,NCPPB 3335,PMP,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,putative membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3727,PHI:2773,UniProt,D7I4C7,ASAP,AER-0004067,,,NCPPB 3335,ampG,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,muropeptide permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3728,PHI:2774,UniProt,D7HVF9,ASAP,AER-0000830,,,NCPPB 3335,cls,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,cardiolipin synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3729,PHI:2775,UniProt,D7HZ46,ASAP,AER-0002177,,,NCPPB 3335,msrA,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,peptide methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3730,PHI:2776,UniProt,D7HWI3,ASAP,AER-0001183,,,NCPPB 3335,ponA,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,multimodular transpeptidase-transglycosylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3731,PHI:2777,UniProt,D7HVM9,ASAP,AER-0000904,,,NCPPB 3335,metF,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,"5,10-methylene-tetrahydrofolate reductase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3732,PHI:2778,UniProt,D7I370,ASAP,AER-0003642,,,NCPPB 3335,iaaH,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,indole acetamide hydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3733,PHI:2779,UniProt,D7HXX4,ASAP,AER-0001745,,,NCPPB 3335,hutG,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,N-formylglutamate deformylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3734,PHI:2780,UniProt,D7HZ26,ASAP,AER-0002156,,,NCPPB 3335,argA,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,N-acetylglutamate synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3735,PHI:2781,UniProt,D7HVL3,ASAP,AER-0000887,,,NCPPB 3335,proC,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,pyrroline-5-carboxylate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3736,PHI:2782,UniProt,D7I202,ASAP,AER-0003214,,,NCPPB 3335,trpE,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,anthranilate synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3737,PHI:2783,UniProt,D7I553,ASAP,AER-0004356,,,NCPPB 3335,hisF,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,imidazole glycerol phosphate synthase cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3738,PHI:2784,UniProt,D7HVL5,ASAP,AER-0000890,,,NCPPB 3335,metW,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,methionine biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3739,PHI:2785,UniProt,D7HV86,ASAP,AER-0000755,,,NCPPB 3335,cioA,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,"cyanide insensitive terminal oxidase, subunit I",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3740,PHI:2786,UniProt,D7I4V6,ASAP,AER-0004257,,,NCPPB 3335,tal,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,transaldolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3741,PHI:2787,UniProt,D7HX82,ASAP,AER-0001487,,,NCPPB 3335,rvsA,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,pseudouridine synthase A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3742,PHI:2788,UniProt,D7HZD8,ASAP,AER-0002272,,,NCPPB 3335,cobB,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,cobyrinic acid-diamide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3743,PHI:2789,UniProt,D7HWR0,ASAP,AER-0001304,,,NCPPB 3335,MCP,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3744,PHI:2790,UniProt,D7HUT1,ASAP,AER-0000594,,,NCPPB 3335,ssb,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,single-stranded DNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3745,PHI:2791,UniProt,D7I5Y7,ASAP,AER-0004647,,,NCPPB 3335,metG,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,methionyl-tRNA synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3746,PHI:2792,UniProt,D7I2L9,ASAP,AER-0003433,,,NCPPB 3335,leuD,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,3-isopropylmalate dehydratase small subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3747,PHI:2793,UniProt,D7I6Y8,ASAP,AER-0005006,,,NCPPB 3335,bioB,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,biotin synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3748,PHI:2794,UniProt,D7HVL9,ASAP,AER-0000894,,,NCPPB 3335,ilvD,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,dihydroxy-acid dehydratase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3749,PHI:2795,UniProt,D7I477,ASAP,AER-0004017,,,NCPPB 3335,hisD,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,histidinol dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3750,PHI:2796,UniProt,D7HUI8,ASAP,AER-0000498,,,NCPPB 3335,ilvC,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,ketol-acid reductoisomerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3751,PHI:2797,UniProt,D7I6Y3,ASAP,AER-0005001,,,NCPPB 3335,bioD,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,dethiobiotin synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3752,PHI:2798,UniProt,D7I145,ASAP,AER-0002900,,,NCPPB 3335,metZ,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,O-acetylhomoserine sulfhydrylase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3753,PHI:2799,UniProt,D7HUI6,ASAP,AER-0000496,,,NCPPB 3335,ilvB,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,acetolactate synthase large subunit,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3754,PHI:2800,UniProt,D7I066,ASAP,AER-0002563,,,NCPPB 3335,hrpR,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,T3SS transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23088618,PubMed,10.1111/j.1469-8137.2012.04357.x,,crr@uma.es,no comments,I M Matas,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3755,PHI:2801,UniProt,Q48WD8,GenBank,AAZ52337,,,MGAS5005,M1,,,,,,,36470,Streptococcus sp. 'group A',36470,5448,gas pharyngitis; neurofibromatosis; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,surface protein and virulence factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,23443671,PubMed,10.1007/s00109-013-1012-6,,annelies.zinkernagel@usz.ch,no comments,S Uchiyama,2013,1 gene,Uchiyama-2013-Coiled-coil irregula,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3756,PHI:2802,UniProt,B2ZRQ4,GenBank,ACD47140,,,St01-23,3hnr,,,,,,,93612,Exserohilum turcicum,671987,Et28A,northern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-N,,,leaf,"1,3,8 trihydroxynaphthalene reductase (3HNR)",,,melanin biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23384859,PubMed,10.1094/PHYTO-08-12-0199-R,,bgt1@cornell.edu,no comments,C Xue,2013,Multi genes,Xue-2013-Efficient gene knock,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3757,PHI:2803,,no data found,,,,,,lae1,,,,,,,93612,Exserohilum turcicum,671987,Et28A,northern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-N,,,leaf,transcriptional regulator of secondary metabolite genes,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23384859,PubMed,10.1094/PHYTO-08-12-0199-R,,bgt1@cornell.edu,no comments,C Xue,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3758,PHI:2804,,no data found,,,,,,ecp6,,,,,,,93612,Exserohilum turcicum,671987,Et28A,northern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-N,,,leaf,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23384859,PubMed,10.1094/PHYTO-08-12-0199-R,,bgt1@cornell.edu,no comments,C Xue,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3759,PHI:2802,UniProt,B2ZRQ4,GenBank,ACD47140,,,St01-23,3hnr,,,,,,,93612,Exserohilum turcicum,671987,Et28A,northern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Pa91,,,leaf,"1,3,8 trihydroxynaphthalene reductase (3HNR)",,,melanin biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23384859,PubMed,10.1094/PHYTO-08-12-0199-R,,bgt1@cornell.edu,no comments,C Xue,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3760,PHI:2803,,no data found,,,,,,lae1,,,,,,,93612,Exserohilum turcicum,671987,Et28A,northern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Pa91,,,leaf,transcriptional regulator of secondary metabolite genes,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23384859,PubMed,10.1094/PHYTO-08-12-0199-R,,bgt1@cornell.edu,no comments,C Xue,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3761,PHI:2804,,no data found,,,,,,ecp6,,,,,,,93612,Exserohilum turcicum,671987,Et28A,northern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Pa91,,,leaf,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23384859,PubMed,10.1094/PHYTO-08-12-0199-R,,bgt1@cornell.edu,no comments,C Xue,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3762,PHI:2805,UniProt,I7F9U1,GenBank,JX399796,,,ZY05719,cbp40,,,,,,,1307,Streptococcus suis,,ZY05719,pneumonia; endocarditis; meningitis; arthritis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,collagen type 1-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,23465548,PubMed,10.1016/j.tvjl.2013.01.030,,fhj@njau.edu.cn,no comments,H Zhang,2013,1 gene,Zhang-2013-Identification of a,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3763,PHI:2806,UniProt,A7E5X4,GenBank,EDN91296,,,1980 UF-70,SsSOD1,,,,,,,5180,Sclerotinia sclerotiorum,1095762,WMA1,,eudicots,3888,Pisum sativum (related: pea),cv. Guido,,,leaf,Cu/Zn superoxide dismutase gene,,,,reduced virulence,,,,,,,,wild type,,no,ZnSO4; H2O2,ZnSO4: CHEBI:35176; H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,23252459,PubMed,10.1094/MPMI-07-12-0177-R,,chen@wsu.edu,Mutants show increased sensitivity to metal and oxidative stress.,L Xu,2013,1 gene,Xu-2013-Random T-DNA Mutagen,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3764,PHI:2806,UniProt,A7E5X4,GenBank,EDN91296,,,1980 UF-70,SsSOD1,,,,,,,5180,Sclerotinia sclerotiorum,1095762,WMA1,,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Great Northern Tara,,,leaf,Cu/Zn superoxide dismutase gene,,,,reduced virulence,,,,,,,,wild type,,no,ZnSO4; H2O2,ZnSO4: CHEBI:35176; H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,23252459,PubMed,10.1094/MPMI-07-12-0177-R,,chen@wsu.edu,Mutants show increased sensitivity to metal and oxidative stress.,L Xu,2013,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3765,PHI:2807,UniProt,A7EKS0,GenBank,XM_001592945,,,1980,Ss-Sl2,,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,melanin formation and cell wall itegrity,,,,unaffected pathogenicity,,,,,,,,wild type; aberrant,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,22558105,PubMed,10.1371/journal.pone.0034962,,yanpingfu@mail .hzau.edu.cn,no comments,Y Yu,2012,1 gene,"Yu-2012-Ss-Sl2, a Novel Cell",Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3766,PHI:2807,UniProt,A7EKS0,GenBank,XM_001592945,,,1980,Ss-Sl2,,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,,eudicots,3708,Brassica napus (related: rape),,,,leaf,melanin formation and cell wall itegrity,,,,unaffected pathogenicity,,,,,,,,wild type; aberrant,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,22558105,PubMed,10.1371/journal.pone.0034962,,yanpingfu@mail .hzau.edu.cn,no comments,Y Yu,2012,,,Batch026,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3767,PHI:2808,UniProt,Q2KN79,GenBank,AY884608,,,,gas1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Vemar,,,leaf; root,"putative beta-1,3-glucanosyltransferase",,,,reduced virulence,,,,yes,,,,reduced,,no,sorbitol,CHEBI:30911,,,,,gene disruption,,,RP,16353549,PubMed,10.1094/MPMI-18-1140,,ge1gorom@uco.es,no comments,Z Caracuel 2005,2005,1 gene,Caracuel-2005-Fusarium oxysporum g,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3768,PHI:2809,UniProt,Q4WPQ8,GenBank,EAL89776,,,Af293,PrtT,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,regulator of extracellular proteolytic activity,,,eIF2 kinase signaling,unaffected pathogenicity,,,,,,,,,,no,bovine serum albumin,,,,,,gene deletion: full; gene complementation,,,RP,19564390,PubMed,10.1128/IAI.00425-09,,sven.krappmann@uni-wuerzburg.de,no comments,A Bergmann 2009,2009,1 gene,Bergmann-2009-A regulator of Asper,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3769,PHI:2810,UniProt,C4MEZ6,GenBank,ACB12685,,,R265,MPK1,,,,,,,552467,Cryptococcus bacillisporus,294750,R265,pulmonary cryptococcosis; basal meningitis; cerebral cryptococcomas,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,regulates cell integrity,,,,reduced virulence,no,,,,,,,defective,,no,caffeine; calcofluor white; congo red,caffeine: CHEBI:27732; calcofluor white: CHEBI:50011; congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,21249145,PubMed,10.1371/journal.pone.0016076,,w.meyer@usyd.edu.au,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,P Ngamskulrungroj 2011,2011,1 gene,Ngamskulrungroj-2011-Cryptococcus gattii,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3770,PHI:2811,UniProt,P19880,GenBank,CAA37827,,,ATCC 204508 / S288c,yap1,,,,,,,4932,Saccharomyces cerevisiae,1247190,BY4741,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,transcription factor of the AP-1 family,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,19502579,PubMed,10.1128/EC.00367-08,,rpr@wpi.edu,no comments,C Jain 2009,2009,Multi gene,Jain-2009-A pathogenesis assay,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3771,PHI:2812,UniProt,P24813,GenBank,AAA02920,,,ATCC 204508 / S288c,yap2,,,,,,,4932,Saccharomyces cerevisiae,1247190,BY4741,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,transcription factor of the AP-1 family,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,19502579,PubMed,10.1128/EC.00367-08,,rpr@wpi.edu,no comments,C Jain 2009,2009,,Jain-2009-A pathogenesis assay,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3772,PHI:2813,UniProt,P00445,GenBank,AAA34543,,,ATCC 204508 / S288c,sod1,,,,,,,4932,Saccharomyces cerevisiae,1247190,BY4741,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,guards cells against oxidative damage by neutralizing reactive oxygen species,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,19502579,PubMed,10.1128/EC.00367-08,,rpr@wpi.edu,no comments,C Jain 2009,2009,,Jain-2009-A pathogenesis assay,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3773,PHI:2814,UniProt,P12383,GenBank,AAA34849,,,ATCC 204508 / S288c,pdr1,,,,,,,4932,Saccharomyces cerevisiae,1247190,BY4741,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,transcription factor and regulates resistance to a variety of drugs,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,19502579,PubMed,10.1128/EC.00367-08,,rpr@wpi.edu,no comments,C Jain 2009,2009,,Jain-2009-A pathogenesis assay,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3774,PHI:2815,UniProt,Q04182,GenBank,AAB64846,,,ATCC 204508 / S288c,pdr15,,,,,,,4932,Saccharomyces cerevisiae,1247190,BY4741,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,ATP binding cassette trans-porter of the plasma membrane implicated in general cellular detoxification,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,19502579,PubMed,10.1128/EC.00367-08,,rpr@wpi.edu,no comments,C Jain 2009,2009,,Jain-2009-A pathogenesis assay,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3775,PHI:2816,UniProt,O42766,GenBank,AF038154,,,SC5314,BMH1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,,,,Lethal pathogen phenotype,,,,,,,,lethal,,,,,,,,reduced,,yes,,,,,,,gene disruption,,,RP,11754483,PubMed,10.1002/yea.804,,sturtevj@georgetown.edu,no comments,D Cognetti 2002,2002,1 gene,Cognetti-2002-The Candida albicans,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3776,PHI:2817,UniProt,Q9C4A0,GenBank,AB047682,,,AC325,Aapg1,,,,,,,5599,Alternaria alternata,,AC325,brown spot,eudicots,64884,Citrus jambhiri (related: rough lemon),,,,leaf,endopolygalacturonase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,11386370,PubMed,10.1094/MPMI.2001.14.6.749,,kazuya@ag.kagawa-u.ac.jp,no comments,A Isshiki 2001,2001,2 genes,Isshiki-2001-Endopolygalacturonas,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3777,PHI:2818,UniProt,Q9C4A1,GenBank,AB047543,,,ATCC 58171,Acpg1,,,,,,,135859,Alternaria citri,,OR1,black rot (Citrus),eudicots,64884,Citrus jambhiri (related: rough lemon),,,,leaf,endopolygalacturonase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,11386370,PubMed,10.1094/MPMI.2001.14.6.749,,kazuya@ag.kagawa-u.ac.jp,no comments,A Isshiki 2001,2001,,Isshiki-2001-Endopolygalacturonas,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3778,PHI:2818,UniProt,Q9C4A1,GenBank,AB047543,,,ATCC 58171,Acpg1,,,,,,,135859,Alternaria citri,,OR1,black rot (Citrus),eudicots,64884,Citrus jambhiri (related: rough lemon),,,,leaf,endopolygalacturonase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,11386370,PubMed,10.1094/MPMI.2001.14.6.749,,kazuya@ag.kagawa-u.ac.jp,no comments,A Isshiki 2001,2001,,Isshiki-2001-Endopolygalacturonas,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3779,PHI:2818,UniProt,Q9C4A1,GenBank,AB047543,,,ATCC 58171,Acpg1,,,,,,,135859,Alternaria citri,,OR1,black rot (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),,,,leaf,endopolygalacturonase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,11386370,PubMed,10.1094/MPMI.2001.14.6.749,,kazuya@ag.kagawa-u.ac.jp,no comments,A Isshiki 2001,2001,,Isshiki-2001-Endopolygalacturonas,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3780,PHI:2818,UniProt,Q9C4A1,GenBank,AB047543,,,ATCC 58171,Acpg1,,,,,,,135859,Alternaria citri,,OR1,black rot (Citrus),eudicots,79217,Citrus iyo (no common name found),,,,leaf,endopolygalacturonase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,11386370,PubMed,10.1094/MPMI.2001.14.6.749,,kazuya@ag.kagawa-u.ac.jp,no comments,A Isshiki 2001,2001,,Isshiki-2001-Endopolygalacturonas,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3781,PHI:2818,UniProt,Q9C4A1,GenBank,AB047543,,,ATCC 58171,Acpg1,,,,,,,135859,Alternaria citri,,OR1,black rot (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,leaf,endopolygalacturonase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,11386370,PubMed,10.1094/MPMI.2001.14.6.749,,kazuya@ag.kagawa-u.ac.jp,no comments,A Isshiki 2001,2001,,Isshiki-2001-Endopolygalacturonas,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3782,PHI:2818,UniProt,Q9C4A1,GenBank,AB047543,,,ATCC 58171,Acpg1,,,,,,,135859,Alternaria citri,,OR1,black rot (Citrus),eudicots,55188,Citrus unshiu (related: satsuma mandarin),,,,leaf,endopolygalacturonase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,11386370,PubMed,10.1094/MPMI.2001.14.6.749,,kazuya@ag.kagawa-u.ac.jp,no comments,A Isshiki 2001,2001,,Isshiki-2001-Endopolygalacturonas,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3783,PHI:2819,UniProt,G1UA02,GenBank,AAK00626,,,,CaEss1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,peptidyl-prolyl cis/trans isomerase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,15835905,PubMed,10.1021/bi050115l,,hanes@wadsworth.org,no comments,Z Li 2005,2005,1 gene,Li-2005-The structure of the,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3784,PHI:2820,UniProt,Q59UR3,GenBank,EAK94221,,,SC5314,SWI1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,filamentous growth regulator,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,16647065,PubMed,10.1016/j.febslet.2006.04.009,,jychen@sunm.shcnc.ac.cn,no comments,X Mao 2006,2006,2 genes,Mao-2006-The Swi_Snf chromati,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3785,PHI:2821,UniProt,Q5ALP9,GenBank,EAL03683,,,SC5314,SNF2,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,filamentous growth regulator,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,16647065,PubMed,10.1016/j.febslet.2006.04.009,,jychen@sunm.shcnc.ac.cn,no comments,X Mao 2006,2006,,Mao-2006-The Swi_Snf chromati,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3786,PHI:2822,UniProt,Q5K8R6,GenBank,ABQ42713,,,Jec21,Cxt1p,,,,,,,5207,Cryptococcus neoformans,214684,JEC21,,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,"B 1,2-xylosyltransferase",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,18347023,PubMed,10.1074/jbc.M708927200,,doering@wustl.edu,no comments,J S Klutts 2008,2008,1 gene,Klutts-2008-Cryptococcal xylosyl,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3787,PHI:2823,UniProt,Q59X38,GenBank,EAK95037,,,SC5314,PES1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,"pescadillo homologs are involved in cell cycle control and ribosome biogenesis, and are essential",,,,reduced virulence,,,,,,,,reduced; defective,,yes,,,,,,,altered gene expression / gene regulation,,,RP,19075239,PubMed,10.1073/pnas.0809147105,,julia.koehler@childrens.harvard.edu,Two different repressible promoters were used to c ontrol ex pression of PES1 in heterozygotes that contain a deletion of one allele and a replacement of the native PES1 promoter of the remain ing allele with the repressible M AL2 or tetO promoters,J Shen 2008,2008,1 gene,Shen-2008-The Candida albicans,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3788,PHI:2824,UniProt,Q59WG7,GenBank,EAK94840,,,SC5314,Cabig1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,"beta-1,6-glucan biosyn-thesis",,,,reduced virulence,,,,,,,,aberrant; defective,,no,,,,,,,gene disruption; gene complementation,,,RP,16552067,PubMed,10.1128/IAI.74.4.2373-2381.2006,,niimi@nih.go.jp,no comments,T Umeyama 2006,2006,1 gene,Umeyama-2006-Deletion of the CaBI,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3789,PHI:2825,UniProt,Q5ABG1,GenBank,EAL00070,,,SC5314,SET1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),Hsd:ICR,,,kidney; liver; spleen,histone 3 lysine 4 methyltransferase,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,16629671,PubMed,10.1111/j.1365-2958.2006.05121.x,,clancyn@medicine.ufl.edu,no comments,S B Raman 2006,2006,1 gene,Raman-2006-Candida albicans SET,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3790,PHI:2826,UniProt,Q6XPX0,GenBank,AY219172,,,,Fgb1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,root; fruit,G-protein subunit,,,cAMP-dependent and -independent pathways,reduced virulence,,,,,,aberrant,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,15588997,PubMed,10.1016/j.fgb.2004.10.001,,ge2dipia@uco.es,no comments,J Delgado-Jarana 2005,2005,2 genes,Delgado-Jarana-2005-Fusarium oxysporum G,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3791,PHI:2827,UniProt,Q9HGU2,GenBank,AF286533_1,,,,Fmk1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,root; fruit,required for virulence,,,cAMP-dependent and -independent pathways,loss of pathogenicity,,,,,,aberrant,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,15588997,PubMed,10.1016/j.fgb.2004.10.001,,ge2dipia@uco.es,no comments,J Delgado-Jarana 2005,2005,,Delgado-Jarana-2005-Fusarium oxysporum G,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3792,PHI:2826,UniProt,Q6XPX0,GenBank,AY219172,,,,Fgb1,,,,,,PHI:2827,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,root; fruit,G-protein subunit,,,cAMP-dependent and -independent pathways,loss of pathogenicity,,,,,,aberrant,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,15588997,PubMed,10.1016/j.fgb.2004.10.001,,ge2dipia@uco.es,no comments,J Delgado-Jarana 2005,2005,,Delgado-Jarana-2005-Fusarium oxysporum G,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3793,PHI:2827,UniProt,Q9HGU2,GenBank,AF286533_1,,,,Fmk1,,,,,,PHI:2826,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,root; fruit,required for virulence,,,cAMP-dependent and -independent pathways,loss of pathogenicity,,,,,,aberrant,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,15588997,PubMed,10.1016/j.fgb.2004.10.001,,ge2dipia@uco.es,no comments,J Delgado-Jarana 2005,2005,,Delgado-Jarana-2005-Fusarium oxysporum G,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3794,PHI:2828,UniProt,Q4WPQ8,GenBank,EAL89776,,,Af293,PrtT,,,,,,,746128,Aspergillus fumigatus,330879,Af293,aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,transcriptor factor involved in the production of secreted protease,,,,unaffected pathogenicity,,,,,,reduced,,,,no,,,,,,,gene disruption,,,RP,19564385,PubMed,10.1128/IAI.00426-09,,nosherov@post.tau.ac.il,no comments,H Sharon 2009,2009,1 gene,Sharon-2009-Transcription factor,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3795,PHI:2829,UniProt,C1KJH7,GenBank,AB520831,,,OS99-G-7a,AVR-Pita1JA,,,,,,,318829,Magnaporthe oryzae,,OS99-G-7a,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sasanishiki BL6,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion,,,RP,20465417,PubMed,10.1094/PHYTO-100-6-0612,,mamitaka@affrc.go.jp,no comments,M Takahashi 2010,2010,2 genes,Takahashi-2010-One of two major par,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3796,PHI:2830,UniProt,C1KJG7,GenBank,AB520830,,,OS99-G-7a,AVR-Pita1JB,,,,,,,318829,Magnaporthe oryzae,,OS99-G-7a,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sasanishiki BL6,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion,,,RP,20465417,PubMed,10.1094/PHYTO-100-6-0612,,mamitaka@affrc.go.jp,no comments,M Takahashi 2010,2010,,Takahashi-2010-One of two major par,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3797,PHI:2831,UniProt,Q9P4V0,GenBank,BAB07810,,,15A,AKTR-1,,,,,,,5599,Alternaria alternata,,15A,black spot (pear),eudicots,23211,Pyrus communis (related: pear),cv. Nijisseiki,,,fruit,AK-toxin biosynthesis,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,RP,10975654,PubMed,10.1094/MPMI.2000.13.9.975,,ttsuge@agr.nagoya-u.ac.jp,no comments,A Tanaka 2000,2000,2 genes,Tanaka-2000-Structural and funct,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3798,PHI:2832,UniProt,Q9P4U9,GenBank,BAB07811,,,15A,AKT3-1,,,,,,,5599,Alternaria alternata,,15A,black spot (pear),eudicots,23211,Pyrus communis (related: pear),cv. Nijisseiki,,,fruit,AK-toxin biosynthesis,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,RP,10975654,PubMed,10.1094/MPMI.2000.13.9.975,,ttsuge@agr.nagoya-u.ac.jp,no comments,A Tanaka 2000,2000,,Tanaka-2000-Structural and funct,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3799,PHI:2833,UniProt,Q09RL3,GenBank,ABG21303,,,B3501A,Cir1,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,iron regulator,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,RP,17121456,PubMed,10.1371/journal.pbio.0040410,,kronstad@interchange.ubc.ca,no comments,W H Jung 2006,2006,1 gene,Jung-2006-Iron regulation of t,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3800,PHI:2834,UniProt,C3PTB1,GenBank,ACP43390,,,C4,LAM1,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative 3-hydroxyacyl-CoA dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,Multi gene,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3801,PHI:2835,UniProt,C3JXE8,GenBank,ACP34152,,,C4,RED2,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3802,PHI:2836,UniProt,C3JXE9,GenBank,ACP34153,,,C4,RED3,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3803,PHI:2837,UniProt,D2SZX7,GenBank,ADB23430,,,C4,OXI1,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3804,PHI:2838,UniProt,D2SZX8,GenBank,ADB23431,,,C4,TOX9,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3805,PHI:2839,UniProt,Q8NJQ2,GenBank,AF525909_2,,,C4,RED1,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3806,PHI:2839,UniProt,Q8NJQ2,GenBank,AF525909_2,,,C4,RED1,,,,,,PHI:2835,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3807,PHI:2835,UniProt,C3JXE8,GenBank,ACP34152,,,C4,RED2,,,,,,PHI:2839,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3808,PHI:2835,UniProt,C3JXE8,GenBank,ACP34152,,,C4,RED2,,,,,,PHI:2836,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3809,PHI:2836,UniProt,C3JXE9,GenBank,ACP34153,,,C4,RED3,,,,,,PHI:2835,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3810,PHI:2835,UniProt,C3JXE8,GenBank,ACP34152,,,C4,RED2,,,,,,PHI:2836; PHI:2839,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3811,PHI:2836,UniProt,C3JXE9,GenBank,ACP34153,,,C4,RED3,,,,,,PHI:2835; PHI:2839,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3812,PHI:2839,UniProt,Q8NJQ2,GenBank,AF525909_2,,,C4,RED1,,,,,,PHI:2835; PHI:2836,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3813,PHI:2837,UniProt,D2SZX7,GenBank,ADB23430,,,C4,OXI1,,,,,,PHI:2838,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3814,PHI:2838,UniProt,D2SZX8,GenBank,ADB23431,,,C4,TOX9,,,,,,PHI:2837,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3815,PHI:2834,UniProt,C3PTB1,GenBank,ACP43390,,,C4,LAM1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative 3-hydroxyacyl-CoA dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3816,PHI:2835,UniProt,C3JXE8,GenBank,ACP34152,,,C4,RED2,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3817,PHI:2836,UniProt,C3JXE9,GenBank,ACP34153,,,C4,RED3,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3818,PHI:2837,UniProt,D2SZX7,GenBank,ADB23430,,,C4,OXI1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3819,PHI:2838,UniProt,D2SZX8,GenBank,ADB23431,,,C4,TOX9,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3820,PHI:2839,UniProt,Q8NJQ2,GenBank,AF525909_2,,,C4,RED1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3821,PHI:2839,UniProt,Q8NJQ2,GenBank,AF525909_2,,,C4,RED1,,,,,,PHI:2835,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3822,PHI:2835,UniProt,C3JXE8,GenBank,ACP34152,,,C4,RED2,,,,,,PHI:2839,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3823,PHI:2835,UniProt,C3JXE8,GenBank,ACP34152,,,C4,RED2,,,,,,PHI:2836,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3824,PHI:2836,UniProt,C3JXE9,GenBank,ACP34153,,,C4,RED3,,,,,,PHI:2835,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3825,PHI:2835,UniProt,C3JXE8,GenBank,ACP34152,,,C4,RED2,,,,,,PHI:2836; PHI:2839,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3826,PHI:2836,UniProt,C3JXE9,GenBank,ACP34153,,,C4,RED3,,,,,,PHI:2835; PHI:2839,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3827,PHI:2839,UniProt,Q8NJQ2,GenBank,AF525909_2,,,C4,RED1,,,,,,PHI:2835; PHI:2836,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3828,PHI:2837,UniProt,D2SZX7,GenBank,ADB23430,,,C4,OXI1,,,,,,PHI:2838,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,putative short chain dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3829,PHI:2838,UniProt,D2SZX8,GenBank,ADB23431,,,C4,TOX9,,,,,,PHI:2837,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,20192833,PubMed,10.1094/MPMI-23-4-0458,,bgt1@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,P Inderbitzin 2010,2010,,Inderbitzin-2010-Six new genes requir,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3830,PHI:2840,UniProt,F6K8L5,GenBank,HM567405,,,H99,CnSEC14-1,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,secretion of phospholipase B1,,,,reduced virulence,,,,,,,,,,no,SDS; calcofluor white,SDS: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene disruption; gene complementation,,,RP,21453402,PubMed,10.1111/j.1365-2958.2011.07632.x,,julie_djordjevic@wmi.usyd.edu.au,The mutants are sensitive to cell wall perturbing agents,M Chayakulkeeree 2011,2011,Multi gene,Chayakulkeeree-2011-SEC14 is a specific,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3831,PHI:2841,UniProt,F6K8L6,GenBank,HM567406,,,H99,CnSEC14-2,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,secretion of phospholipase B1,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; calcofluor white,SDS: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene disruption; gene complementation,,,RP,21453402,PubMed,10.1111/j.1365-2958.2011.07632.x,,julie_djordjevic@wmi.usyd.edu.au,The mutants are sensitive to cell wall perturbing agents,M Chayakulkeeree 2011,2011,,Chayakulkeeree-2011-SEC14 is a specific,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3832,PHI:2842,UniProt,F6K8L7,GenBank,HM567407,,,H99,CnSFH5,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,secretion of phospholipase B1,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; calcofluor white,SDS: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene disruption; gene complementation,,,RP,21453402,PubMed,10.1111/j.1365-2958.2011.07632.x,,julie_djordjevic@wmi.usyd.edu.au,The mutants are sensitive to cell wall perturbing agents,M Chayakulkeeree 2011,2011,,Chayakulkeeree-2011-SEC14 is a specific,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3833,PHI:2843,UniProt,Q9P8P2,GenBank,AF223383_1,,,H99,CnPlb1,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,secretion of phospholipase B1,,,,reduced virulence,,,,,,,,,,no,SDS; calcofluor white,SDS: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene disruption; gene complementation,,,RP,21453402,PubMed,10.1111/j.1365-2958.2011.07632.x,,julie_djordjevic@wmi.usyd.edu.au,The mutants are sensitive to cell wall perturbing agents,M Chayakulkeeree 2011,2011,,Chayakulkeeree-2011-SEC14 is a specific,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3834,PHI:2840,UniProt,F6K8L5,GenBank,HM567405,,,H99,CnSEC14-1,,,,,,PHI:2842,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,secretion of phospholipase B1,,,,reduced virulence,,,,,,,,,,no,SDS; calcofluor white,SDS: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene disruption; gene complementation,,,RP,21453402,PubMed,10.1111/j.1365-2958.2011.07632.x,,julie_djordjevic@wmi.usyd.edu.au,The mutants are sensitive to cell wall perturbing agents,M Chayakulkeeree 2011,2011,,Chayakulkeeree-2011-SEC14 is a specific,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3835,PHI:2842,UniProt,F6K8L7,GenBank,HM567407,,,H99,CnSFH5,,,,,,PHI:2840,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,secretion of phospholipase B1,,,,reduced virulence,,,,,,,,,,no,SDS; calcofluor white,SDS: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene disruption; gene complementation,,,RP,21453402,PubMed,10.1111/j.1365-2958.2011.07632.x,,julie_djordjevic@wmi.usyd.edu.au,The mutants are sensitive to cell wall perturbing agents,M Chayakulkeeree 2011,2011,,Chayakulkeeree-2011-SEC14 is a specific,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3836,PHI:2841,UniProt,F6K8L6,GenBank,HM567406,,,H99,CnSEC14-2,,,,,,PHI:2842,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,secretion of phospholipase B1,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; calcofluor white,SDS: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene disruption; gene complementation,,,RP,21453402,PubMed,10.1111/j.1365-2958.2011.07632.x,,julie_djordjevic@wmi.usyd.edu.au,The mutants are sensitive to cell wall perturbing agents,M Chayakulkeeree 2011,2011,,Chayakulkeeree-2011-SEC14 is a specific,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3837,PHI:2842,UniProt,F6K8L7,GenBank,HM567407,,,H99,CnSFH5,,,,,,PHI:2841,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,secretion of phospholipase B1,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; calcofluor white,SDS: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene disruption; gene complementation,,,RP,21453402,PubMed,10.1111/j.1365-2958.2011.07632.x,,julie_djordjevic@wmi.usyd.edu.au,The mutants are sensitive to cell wall perturbing agents,M Chayakulkeeree 2011,2011,,Chayakulkeeree-2011-SEC14 is a specific,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3838,PHI:2844,UniProt,O93802,GenBank,AB015743,,,15A,BRM2,,,,,,,5599,Alternaria alternata,,15A,black spot (pear),eudicots,23211,Pyrus communis (related: pear),cv. Nijisseiki,,,leaf,"1,3,8-trihydroxynaphthalene reductase",,,,unaffected pathogenicity,,,,,,wild type; aberrant,,wild type,,no,,,,,,,gene disruption,,,RP,9885194,PubMed,10.1094/MPMI.1999.12.1.59,,ttsuge@agr.nagoya-u.ac.jp,no comments,C Kawamura 1999,1999,1 gene,Kawamura-1999-Targeted disruption,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3839,PHI:2845,UniProt,P22287,GenBank,AAA03344,,,,avr9,,,,,,,5499,Fulvia fulva,,race 5,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,1303800,PubMed,10.1046/j.1365-313X.1992.t01-34-00999.x,,,no comments,Guido et al.,1992,1 gene,Van den Ackerveken-1992-Molecular analysis o,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3840,PHI:2846,UniProt,Q5RZ66,GenBank,AY796185,,,,TRR1,,,,,,,5207,Cryptococcus neoformans,235443,H99,,,,,Lethal pathogen phenotype,,,,thioredoxin reductase,,,,lethal,,,,,,,,reduced,,yes,,,,,,,altered gene expression / gene regulation,,,RP,15701811,PubMed,10.1128/EC.4.2.487-489.2005,,lodgejk@slu.edu,no comments,T A Missall 2005,2005,1 gene,Missall-2005-Thioredoxin reductas,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3841,PHI:2847,UniProt,A7X4J2,GenBank,EF195774,,,T7,BcPG1,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,polygalacturonase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,natural sequence variation,,,RP,17849715,PubMed,10.1094/MPMI-20-9-1126,,Kliebenstein@ucdavis.edu,no comments,H C Rowe 2007,2007,2 genes,Rowe-2007-Elevated genetic var,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3842,PHI:2848,UniProt,A4VB48,GenBank,ABP88773,,,GLO1,BcPG2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,polygalacturonase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,natural sequence variation,,,RP,17849715,PubMed,10.1094/MPMI-20-9-1126,,Kliebenstein@ucdavis.edu,no comments,H C Rowe 2007,2007,,Rowe-2007-Elevated genetic var,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3843,PHI:2849,UniProt,Q99174,GenBank,AAB05922,,,PGB153,cutA,,,,,,,169388,Fusarium solani,1344347,f. sp. cucurbitae strain PGB153,storage rot,eudicots,3661,Cucurbita maxima (related: winter squash),cv. Crown,,,fruit,cutinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,9100380,PubMed,10.1094/MPMI.1997.10.3.355,,RCrowhurst@hort.cri.nz,no comments,R N Crowhurst 1997,1997,1 gene,Crowhurst-1997-Effect of disruption,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3844,PHI:2849,UniProt,Q99174,GenBank,AAB05922,,,PGB153,cutA,,,,,,,169388,Fusarium solani,1344347,f. sp. cucurbitae strain PGB153,storage rot,eudicots,3661,Cucurbita maxima (related: winter squash),cv. Delica,,,fruit,cutinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,9100380,PubMed,10.1094/MPMI.1997.10.3.355,,RCrowhurst@hort.cri.nz,no comments,R N Crowhurst 1997,1997,,Crowhurst-1997-Effect of disruption,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3845,PHI:2849,UniProt,Q99174,GenBank,AAB05922,,,PGB153,cutA,,,,,,,169388,Fusarium solani,1344347,f. sp. cucurbitae strain PGB153,storage rot,eudicots,3661,Cucurbita maxima (related: winter squash),cv. Triamble,,,fruit,cutinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,9100380,PubMed,10.1094/MPMI.1997.10.3.355,,RCrowhurst@hort.cri.nz,no comments,R N Crowhurst 1997,1997,,Crowhurst-1997-Effect of disruption,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3846,PHI:2849,UniProt,Q99174,GenBank,AAB05922,,,PGB153,cutA,,,,,,,169388,Fusarium solani,1344347,f. sp. cucurbitae strain PGB153,storage rot,eudicots,3662,Cucurbita moschata (related: crookneck pumpkin),,,,fruit,cutinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,9100380,PubMed,10.1094/MPMI.1997.10.3.355,,RCrowhurst@hort.cri.nz,no comments,R N Crowhurst 1997,1997,,Crowhurst-1997-Effect of disruption,Batch027,2013-04-01,MC,,,,,,,,,,,,,
,,Record 3847,PHI:2850,UniProt,C1KJH9,GenBank,ACO58459,,,91T59,AVR-Pita1,,,,,,,318829,Magnaporthe oryzae,,O-137,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Katy,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion,,,RP,20719251,PubMed,10.1016/j.fgb.2010.08.003,,Yulin.Jia@ars.usda.gov,no comments,Y Dai 2010,2010,1 gene,Dai-2010-Diversification and,Batch027,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3848,PHI:2850,UniProt,C1KJH9,GenBank,ACO58459,,,91T59,AVR-Pita1,,,,,,,318829,Magnaporthe oryzae,,O-137,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Drew,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion,,,RP,20719251,PubMed,10.1016/j.fgb.2010.08.003,,Yulin.Jia@ars.usda.gov,no comments,Y Dai 2010,2010,1 gene,Dai-2010-Diversification and,Batch027,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3849,PHI:2851,UniProt,Q58ID3,GenBank,AAX47479,,,,Mig2-6,chromosome 21,,,,,PHI:2852; PHI:2853; PHI:2854; PHI:2855; PHI:2856,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,leaf,cis-active elements,,,,unaffected pathogenicity,no,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,15672821,PubMed,10.1094/MPMI-18-0075,,basse@staff.uni-marburg.de,no comments,J W Farfsing 2005,2005,Multi gene,Farfsing-2005-Identification of ci,Batch027,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3850,PHI:2852,UniProt,Q9UV32,GenBank,AAF24760,,,,Mig1,,,,,,PHI:2851; PHI:2853; PHI:2854; PHI:2855; PHI:2856,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,leaf,cis-active elements,,,,unaffected pathogenicity,no,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,15672821,PubMed,10.1094/MPMI-18-0075,,basse@staff.uni-marburg.de,no comments,J W Farfsing 2005,2005,,Farfsing-2005-Identification of ci,Batch027,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3851,PHI:2853,UniProt,Q8X1D5,GenBank,AAL67330,,,,Mig2-4,,,,,,PHI:2851; PHI:2852; PHI:2854; PHI:2855; PHI:2856,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,leaf,cis-active elements,,,,unaffected pathogenicity,no,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,15672821,PubMed,10.1094/MPMI-18-0075,,basse@staff.uni-marburg.de,no comments,J W Farfsing 2005,2005,,Farfsing-2005-Identification of ci,Batch027,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3852,PHI:2854,UniProt,Q8X1D7,GenBank,AAL67328,,,,mig2-1,,,,,,PHI:2851; PHI:2852; PHI:2853; PHI:2855; PHI:2856,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,leaf,cis-active elements,,,,unaffected pathogenicity,no,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,15672821,PubMed,10.1094/MPMI-18-0075,,basse@staff.uni-marburg.de,no comments,J W Farfsing 2005,2005,,Farfsing-2005-Identification of ci,Batch027,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3853,PHI:2855,UniProt,Q8X1D4,GenBank,AAL67331,,,,mig2-5,,,,,,PHI:2851; PHI:2852; PHI:2853; PHI:2854; PHI:2856,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,leaf,cis-active elements,,,,unaffected pathogenicity,no,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,15672821,PubMed,10.1094/MPMI-18-0075,,basse@staff.uni-marburg.de,no comments,J W Farfsing 2005,2005,,Farfsing-2005-Identification of ci,Batch027,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3854,PHI:2856,UniProt,Q8X1D6,GenBank,AAL67329,,,,mig2-2,,,,,,PHI:2851; PHI:2852; PHI:2853; PHI:2854; PHI:2855,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,leaf,cis-active elements,,,,unaffected pathogenicity,no,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,15672821,PubMed,10.1094/MPMI-18-0075,,basse@staff.uni-marburg.de,no comments,J W Farfsing 2005,2005,,Farfsing-2005-Identification of ci,Batch027,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3855,PHI:2857,UniProt,I8LT72,GenBank,EIS88482,,,PY-66,YopK,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,coordinate inflammatory response during pneumonic plague through regulation of apoptosis of immune cells,,,intrinsic and extrinsic apoptosis pathways,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,23633954,PubMed,10.1371/journal.ppat.1003324,,andersondeb@missouri.edu,no comments,K N Peters 2013,2013,1 gene,ppat.1003324,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3856,PHI:2858,UniProt,A0MAR2,GenBank,ABC02879,,,,FvVE1,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,seedling,biosynthesis of mycotoxins and other secondary metabolites,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,22247572,PubMed,10.1111/j.1365-3059.2011.02504.x,,amcalvo@niu.edu,no comments,K Myung 2013,2013,1 gene,nihms314560,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3857,PHI:2858,UniProt,A0MAR2,GenBank,ABC02879,,,,FvVE1,,,,,,,117187,Fusarium verticillioides,,M-3120,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,seedling,biosynthesis of mycotoxins and other secondary metabolites,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,22247572,PubMed,10.1111/j.1365-3059.2011.02504.x,,amcalvo@niu.edu,no comments,K Myung 2013,2013,,nihms314560,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3858,PHI:2859,UniProt,Q5APP3,GenBank,EAL04514,,,SC5314,Rtg1,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract; whole body,transcription regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23526879,PubMed,10.1371/journal.pbio.1001510,,jperez@ucsf.edu,no comments,J C Perez 2013,2013,Multi genes,pbio.1001510,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3859,PHI:2860,UniProt,Q59WI6,GenBank,EAK94821,,,SC5314,Rtg3,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract; whole body,transcription regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23526879,PubMed,10.1371/journal.pbio.1001510,,jperez@ucsf.edu,no comments,J C Perez 2013,2013,,pbio.1001510,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3860,PHI:2861,UniProt,Q59RL7,GenBank,EAK93265,,,SC5314,Hms1,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract; whole body,transcription regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23526879,PubMed,10.1371/journal.pbio.1001510,,jperez@ucsf.edu,no comments,J C Perez 2013,2013,,pbio.1001510,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3861,PHI:2862,UniProt,Q5AC02,GenBank,EAL00215,,,SC5314,Lys14,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract; whole body,transcription regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23526879,PubMed,10.1371/journal.pbio.1001510,,jperez@ucsf.edu,no comments,J C Perez 2013,2013,,pbio.1001510,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3862,PHI:2863,UniProt,Q5A7T6,GenBank,EAK98701,,,SC5314,Lys144,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract; whole body,transcription regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23526879,PubMed,10.1371/journal.pbio.1001510,,jperez@ucsf.edu,no comments,J C Perez 2013,2013,,pbio.1001510,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3863,PHI:2864,UniProt,Q59SK6,GenBank,EAK93445,,,SC5314,Zcf21,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract; whole body,transcription regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23526879,PubMed,10.1371/journal.pbio.1001510,,jperez@ucsf.edu,no comments,J C Perez 2013,2013,,pbio.1001510,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3864,PHI:2865,UniProt,Q5AL36,GenBank,EAL03378,,,SC5314,Tye7,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract; whole body,transcription regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23526879,PubMed,10.1371/journal.pbio.1001510,,jperez@ucsf.edu,no comments,J C Perez 2013,2013,,pbio.1001510,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3865,PHI:2866,UniProt,Q59Y24,GenBank,EAK95405,,,SC5314,ORF19.3625,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract; whole body,transcription regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23526879,PubMed,10.1371/journal.pbio.1001510,,jperez@ucsf.edu,no comments,J C Perez 2013,2013,,pbio.1001510,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3866,PHI:2867,UniProt,Q59YG3,GenBank,EAK95482,,,SC5314,orf19.1363,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,,,,Lethal pathogen phenotype,,,,,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,23526879,PubMed,10.1371/journal.pbio.1001510,,jperez@ucsf.edu,no comments,J C Perez 2013,2013,,pbio.1001510,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3867,PHI:2868,UniProt,F0UYY1,GenBank,ADC97940,,,278/06,acpA,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,Multi genes,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3868,PHI:2869,UniProt,Q5NIC0,GenBank,CAG44789,,,SCHU S4,acpB,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3869,PHI:2870,UniProt,Q5NH51,GenBank,CAG45253,,,SCHU S4,acpC,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3870,PHI:2871,UniProt,Q5NFZ7,GenBank,CAG45697,,,SCHU S4,hapA,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3871,PHI:2868,UniProt,F0UYY1,GenBank,ADC97940,,,278/06,acpA,,,,,,PHI:2869,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3872,PHI:2869,UniProt,Q5NIC0,GenBank,CAG44789,,,SCHU S4,acpB,,,,,,PHI:2868,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3873,PHI:2868,UniProt,F0UYY1,GenBank,ADC97940,,,278/06,acpA,,,,,,PHI:2870,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3874,PHI:2870,UniProt,Q5NH51,GenBank,CAG45253,,,SCHU S4,acpC,,,,,,PHI:2868,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3875,PHI:2869,UniProt,Q5NIC0,GenBank,CAG44789,,,SCHU S4,acpB,,,,,,PHI:2870,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3876,PHI:2870,UniProt,Q5NH51,GenBank,CAG45253,,,SCHU S4,acpC,,,,,,PHI:2869,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3877,PHI:2868,UniProt,F0UYY1,GenBank,ADC97940,,,278/06,acpA,,,,,,PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3878,PHI:2871,UniProt,Q5NFZ7,GenBank,CAG45697,,,SCHU S4,hapA,,,,,,PHI:2868,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3879,PHI:2869,UniProt,Q5NIC0,GenBank,CAG44789,,,SCHU S4,acpB,,,,,,PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3880,PHI:2871,UniProt,Q5NFZ7,GenBank,CAG45697,,,SCHU S4,hapA,,,,,,PHI:2869,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3881,PHI:2870,UniProt,Q5NH51,GenBank,CAG45253,,,SCHU S4,acpC,,,,,,PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3882,PHI:2871,UniProt,Q5NFZ7,GenBank,CAG45697,,,SCHU S4,hapA,,,,,,PHI:2870,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3883,PHI:2868,UniProt,F0UYY1,GenBank,ADC97940,,,278/06,acpA,,,,,,PHI:2869; PHI:2870,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3884,PHI:2869,UniProt,Q5NIC0,GenBank,CAG44789,,,SCHU S4,acpB,,,,,,PHI:2868; PHI:2870,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3885,PHI:2870,UniProt,Q5NH51,GenBank,CAG45253,,,SCHU S4,acpC,,,,,,PHI:2868; PHI:2869,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3886,PHI:2868,UniProt,F0UYY1,GenBank,ADC97940,,,278/06,acpA,,,,,,PHI:2870; PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3887,PHI:2870,UniProt,Q5NH51,GenBank,CAG45253,,,SCHU S4,acpC,,,,,,PHI:2868; PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3888,PHI:2871,UniProt,Q5NFZ7,GenBank,CAG45697,,,SCHU S4,hapA,,,,,,PHI:2870; PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3889,PHI:2869,UniProt,Q5NIC0,GenBank,CAG44789,,,SCHU S4,acpB,,,,,,PHI:2870; PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3890,PHI:2870,UniProt,Q5NH51,GenBank,CAG45253,,,SCHU S4,acpC,,,,,,PHI:2869; PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3891,PHI:2871,UniProt,Q5NFZ7,GenBank,CAG45697,,,SCHU S4,hapA,,,,,,PHI:2870; PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3892,PHI:2868,UniProt,F0UYY1,GenBank,ADC97940,,,278/06,acpA,,,,,,PHI:2869; PHI:2870; PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3893,PHI:2869,UniProt,Q5NIC0,GenBank,CAG44789,,,SCHU S4,acpB,,,,,,PHI:2868; PHI:2870; PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3894,PHI:2870,UniProt,Q5NH51,GenBank,CAG45253,,,SCHU S4,acpC,,,,,,PHI:2868; PHI:2869; PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3895,PHI:2871,UniProt,Q5NFZ7,GenBank,CAG45697,,,SCHU S4,hapA,,,,,,PHI:2869; PHI:2870; PHI:2871,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,acid phosphatase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23457625,PubMed,10.1371/journal.pone.0056834,,gunn.43@osu.edu,no comments,N P Mohapatra 2013,2013,,pone.0056834,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3896,PHI:2872,UniProt,Q48473,GenBank,CAA83913,,,C3,ompK36,,,,,,,573,Klebsiella pneumoniae,,Kp52.145,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6JOlaHsd,,,trachea; lung,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23457627,PubMed,10.1371/journal.pone.0056847,,bengoechea@caubet-cimera.es,no comments,C March 2013,2013,1 gene,pone.0056847,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3897,PHI:2873,UniProt,D3FN03,GenBank,ADC28729,,,IA3902,hldD,,,,,,,197,Campylobacter jejuni,,11-164,diarrhea,birds,9031,Gallus gallus (related: chicken),,,,cecum,lipooligosaccharide,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,23437265,PubMed,10.1371/journal.pone.0056900,,akiba@affrc.go.jp,no comments,T Iwata 2013,2013,1 gene,pone.0056900,Batch028,2013-05-01,MC,,,,,,,,,,,,,
,,Record 3898,PHI:2874,UniProt,Q4ZXM6,GenBank,AAY36096,,,B728a,ecf5,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blue Lake 274,,,leaf,FecI-type ECF sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23516563,PubMed,10.1371/journal.pone.0058846,,d-gross@tamu.edu,no comments,P B Thakur 2013,2013,Multi genes,pone.0058846,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3899,PHI:2875,UniProt,Q4ZXG1,GenBank,AAY36161,,,B728a,ecf7,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blue Lake 274,,,leaf,FecI-type ECF sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23516563,PubMed,10.1371/journal.pone.0058846,,d-gross@tamu.edu,no comments,P B Thakur 2013,2013,,pone.0058846,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3900,PHI:2876,UniProt,Q4ZM64,GenBank,AAY39758,,,B728a,ecf6,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blue Lake 274,,,leaf,FecI-type ECF sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23516563,PubMed,10.1371/journal.pone.0058846,,d-gross@tamu.edu,no comments,P B Thakur 2013,2013,,pone.0058846,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3901,PHI:2877,UniProt,Q4ZY22,GenBank,AAY35950,,,B728a,ecf11,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blue Lake 274,,,leaf,ECF sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23516563,PubMed,10.1371/journal.pone.0058846,,d-gross@tamu.edu,no comments,P B Thakur 2013,2013,,pone.0058846,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3902,PHI:2878,UniProt,Q4ZZI8,GenBank,AAY35434,,,B728a,ecf18,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blue Lake 274,,,leaf,ECF sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23516563,PubMed,10.1371/journal.pone.0058846,,d-gross@tamu.edu,no comments,P B Thakur 2013,2013,,pone.0058846,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3903,PHI:2879,UniProt,Q888Y7,GenBank,AAO54411,,,DC3000,HopQ1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,flower,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23555744,PubMed,10.1371/journal.pone.0059684,,glcoaker@ucdavis.edu,Agrobacterium tumefaciens strain GV3101,W Li 2013,2013,1 gene,pone.0059684,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3904,PHI:2879,UniProt,Q888Y7,GenBank,AAO54411,,,DC3000,HopQ1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23555744,PubMed,10.1371/journal.pone.0059684,,glcoaker@ucdavis.edu,Agrobacterium tumefaciens strain GV3101,W Li 2013,2013,,pone.0059684,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3905,PHI:2879,UniProt,Q888Y7,GenBank,AAO54411,,,DC3000,HopQ1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23555744,PubMed,10.1371/journal.pone.0059684,,glcoaker@ucdavis.edu,Agrobacterium tumefaciens strain GV3101,W Li 2013,2013,,pone.0059684,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3906,PHI:2880,UniProt,Q48S75,GenBank,AAX72435,,,MGAS6180,AspA,,,,,,,1314,Streptococcus pyogenes,319701,MGAS6180,pharyngitis; toxic shock syndrome; sepsis,rodents,10090,Mus musculus (related: house mouse),MF1,,,lung,AgI/I I family adhesin protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23638083,PubMed,10.1371/journal.pone.0062433,,a.kadioglu@liv.ac.uk,no comments,L Franklin 2013,2013,1 gene,pone.0062433,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3907,PHI:2880,UniProt,Q48S75,GenBank,AAX72435,,,MGAS6180,AspA,,,,,,,1314,Streptococcus pyogenes,370552,MGAS10270,pharyngitis; toxic shock syndrome; sepsis,rodents,10090,Mus musculus (related: house mouse),MF1,,,lung,AgI/I I family adhesin protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23638083,PubMed,10.1371/journal.pone.0062433,,a.kadioglu@liv.ac.uk,no comments,L Franklin 2013,2013,,pone.0062433,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3908,PHI:2881,UniProt,I2E6J4,GenBank,AFJ93332,,,Pa 2/3,Gp-flp-32,,,,,,,36090,Globodera pallida,,Pa 2/3,cyst (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,neuropeptide,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23468621,PubMed,10.1371/journal.ppat.1003169,,a.mousley@qub.ac.uk,no comments,L E Atkinson 2013,2013,1 gene,ppat.1003169,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3909,PHI:2882,UniProt,D5MS78,GenBank,BAJ06379,,,16K,psm-mec,,,,,,,1280,Staphylococcus aureus,,NI-13,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Hos:HR-1,,,skin,suppress translation of agrA and attenuate MRSA virulence,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23592990,PubMed,10.1371/journal.ppat.1003269,,kaito@mol.f.u-tokyo.ac.jp,no comments,C Kaito 2013,2013,1 gene,ppat.1003269,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3910,PHI:2882,UniProt,D5MS78,GenBank,BAJ06379,,,16K,psm-mec,,,,,,,1280,Staphylococcus aureus,,NI-13,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),ICR,,,whole body,suppress translation of agrA and attenuate MRSA virulence,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23592990,PubMed,10.1371/journal.ppat.1003269,,kaito@mol.f.u-tokyo.ac.jp,no comments,C Kaito 2013,2013,,ppat.1003269,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3911,PHI:2883,UniProt,Q59WF4,GenBank,EAK94912,,,SC5314,MNN2,,,,,,PHI:2884; PHI:2885; PHI:2886; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,Multi genes,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3912,PHI:2884,UniProt,Q59KJ7,GenBank,EAK91003,,,SC5314,MNN21,,,,,,PHI:2883; PHI:2885; PHI:2886; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3913,PHI:2885,UniProt,Q5AD72,GenBank,EAL00561,,,SC5314,MNN22,,,,,,PHI:2883; PHI:2884; PHI:2886; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3914,PHI:2886,UniProt,Q5AP90,GenBank,EAL04667,,,SC5314,MNN23,,,,,,PHI:2883; PHI:2884; PHI:2885; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3915,PHI:2887,UniProt,Q5A687,GenBank,EAK98234,,,SC5314,MNN24,,,,,,PHI:2883; PHI:2884; PHI:2885; PHI:2886; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3916,PHI:2888,UniProt,Q59R28,GenBank,EAK92925,,,SC5314,MNN26,,,,,,PHI:2883; PHI:2884; PHI:2885; PHI:2886; PHI:2887,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3917,PHI:2883,UniProt,Q59WF4,GenBank,EAK94912,,,SC5314,MNN2,,,,,,PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3918,PHI:2888,UniProt,Q59R28,GenBank,EAK92925,,,SC5314,MNN26,,,,,,PHI:2883,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3919,PHI:2883,UniProt,Q59WF4,GenBank,EAK94912,,,SC5314,MNN2,,,,,,,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3920,PHI:2885,UniProt,Q5AD72,GenBank,EAL00561,,,SC5314,MNN22,,,,,,,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3921,PHI:2887,UniProt,Q5A687,GenBank,EAK98234,,,SC5314,MNN24,,,,,,,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3922,PHI:2883,UniProt,Q59WF4,GenBank,EAK94912,,,SC5314,MNN2,,,,,,PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3923,PHI:2888,UniProt,Q59R28,GenBank,EAK92925,,,SC5314,MNN26,,,,,,PHI:2883,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3924,PHI:2883,UniProt,Q59WF4,GenBank,EAK94912,,,SC5314,MNN2,,,,,,PHI:2884; PHI:2885; PHI:2886; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3925,PHI:2884,UniProt,Q59KJ7,GenBank,EAK91003,,,SC5314,MNN21,,,,,,PHI:2883; PHI:2885; PHI:2886; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3926,PHI:2885,UniProt,Q5AD72,GenBank,EAL00561,,,SC5314,MNN22,,,,,,PHI:2883; PHI:2884; PHI:2886; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3927,PHI:2886,UniProt,Q5AP90,GenBank,EAL04667,,,SC5314,MNN23,,,,,,PHI:2883; PHI:2884; PHI:2885; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3928,PHI:2887,UniProt,Q5A687,GenBank,EAK98234,,,SC5314,MNN24,,,,,,PHI:2883; PHI:2884; PHI:2885; PHI:2886; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3929,PHI:2888,UniProt,Q59R28,GenBank,EAK92925,,,SC5314,MNN26,,,,,,PHI:2883; PHI:2884; PHI:2885; PHI:2886; PHI:2887,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3930,PHI:2883,UniProt,Q59WF4,GenBank,EAK94912,,,SC5314,MNN2,,,,,,PHI:2885; PHI:2886; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3931,PHI:2885,UniProt,Q5AD72,GenBank,EAL00561,,,SC5314,MNN22,,,,,,PHI:2883; PHI:2886; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3932,PHI:2886,UniProt,Q5AP90,GenBank,EAL04667,,,SC5314,MNN23,,,,,,PHI:2883; PHI:2885; PHI:2887; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3933,PHI:2887,UniProt,Q5A687,GenBank,EAK98234,,,SC5314,MNN24,,,,,,PHI:2883; PHI:2885; PHI:2886; PHI:2888,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3934,PHI:2888,UniProt,Q59R28,GenBank,EAK92925,,,SC5314,MNN26,,,,,,PHI:2883; PHI:2885; PHI:2886; PHI:2887,5476,Candida albicans,,CAI-4+CIp10,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mannosyltransferase family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633946,PubMed,10.1371/journal.ppat.1003276,,n.gow@abdn.ac.uk,no comments,R A Hall 2013,2013,,ppat.1003276,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3935,PHI:2889,UniProt,Q0GBR6,GenBank,ABI35958,,,CTG; CEP,Rop18,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,serine threonine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633952,PubMed,10.1371/journal.ppat.1003320,,sibley@wustl.edu,no comments,E M Selleck 2013,2013,1 gene,ppat.1003320,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3936,PHI:2889,UniProt,Q0GBR6,GenBank,ABI35958,,,CTG; CEP,Rop18,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),Gbp<-/->,,,,serine threonine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23633952,PubMed,10.1371/journal.ppat.1003320,,sibley@wustl.edu,no comments,E M Selleck 2013,2013,,ppat.1003320,Batch028,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3937,PHI:2890,UniProt,B2C6F5,GenBank,KC312950,,,P7063,Avr1k,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,2 genes,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3938,PHI:2891,UniProt,G4ZRQ8,GenBank,KC312957,,,P7064,Avr1b-1,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3939,PHI:2890,UniProt,B2C6F5,GenBank,KC312950,,,P7063,Avr1k,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3940,PHI:2891,UniProt,G4ZRQ8,GenBank,KC312957,,,P7064,Avr1b-1,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3941,PHI:2890,UniProt,B2C6F5,GenBank,KC312950,,,P7063,Avr1k,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3942,PHI:2891,UniProt,G4ZRQ8,GenBank,KC312957,,,P7064,Avr1b-1,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3943,PHI:2890,UniProt,B2C6F5,GenBank,KC312950,,,P7063,Avr1k,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3944,PHI:2891,UniProt,G4ZRQ8,GenBank,KC312957,,,P7064,Avr1b-1,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3945,PHI:2890,UniProt,B2C6F5,GenBank,KC312950,,,P7063,Avr1k,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3946,PHI:2891,UniProt,G4ZRQ8,GenBank,KC312957,,,P7064,Avr1b-1,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3947,PHI:2890,UniProt,B2C6F5,GenBank,KC312950,,,P7063,Avr1k,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3948,PHI:2891,UniProt,G4ZRQ8,GenBank,KC312957,,,P7064,Avr1b-1,,,,,,,67593,Phytophthora sojae,,P6954,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23530601,PubMed,10.1094/MPMI-12-12-0289-R,,brett.tyler@oregonstate.edu,Avirulence phenotype in the presence of Rps1k in soybean,T Song 2013,2013,,Song-2013-Two RxLR Avirulence,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3949,PHI:2892,UniProt,B9K1X3,GenBank,ACM38871,,,S4,F-Avi5813,chromosome 2,,,,,,373,Agrobacterium vitis,,F2/5,crown gall (grape),eudicots,29760,Vitis vinifera (related: wine grape),,,,shoot,phosphopantetheinyl transferase,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,23581823,PubMed,10.1094/MPMI-12-12-0295-R,,tjb1@cornell.edu,no comments,D Zheng 2013,2013,Multi genes,Zheng-2013-An Sfp-Type PPTase a,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3950,PHI:2893,UniProt,B9K1Q7,GenBank,ACM38805,,,S4,F-avi5730,chromosome 2,,,,,,373,Agrobacterium vitis,,F2/5,crown gall (grape),eudicots,29760,Vitis vinifera (related: wine grape),,,,shoot,peptide synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23581823,PubMed,10.1094/MPMI-12-12-0295-R,,tjb1@cornell.edu,no comments,D Zheng 2013,2013,,Zheng-2013-An Sfp-Type PPTase a,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3951,PHI:2894,UniProt,B9JZT5,GenBank,ACM37395,,,S4,F-avi3342,chromosome 1,,,,,,373,Agrobacterium vitis,,F2/5,crown gall (grape),eudicots,29760,Vitis vinifera (related: wine grape),,,,shoot,peptide synthetase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23581823,PubMed,10.1094/MPMI-12-12-0295-R,,tjb1@cornell.edu,no comments,D Zheng 2013,2013,,Zheng-2013-An Sfp-Type PPTase a,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3952,PHI:2895,UniProt,B9JV05,GenBank,ACM38143,,,S4,F-avi4330,chromosome 1,,,,,,373,Agrobacterium vitis,,F2/5,crown gall (grape),eudicots,29760,Vitis vinifera (related: wine grape),,,,shoot,polyketide synthetase protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23581823,PubMed,10.1094/MPMI-12-12-0295-R,,tjb1@cornell.edu,no comments,D Zheng 2013,2013,,Zheng-2013-An Sfp-Type PPTase a,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3953,PHI:2896,UniProt,N1JK84,EMBL,CCU82697,,,,BEC1005,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei strain CH4.8,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23441578,PubMed,10.1094/MPMI-01-13-0005-R,,p.spanu@imperial.ac.uk,no comments,C Pliego 2013,2013,Multi genes,Pliego-2013-Host-induced gene si,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3954,PHI:2897,UniProt,A0A059UDR8,GenBank,KJ571201.1,,,,BEC1019,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei strain CH4.8,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23441578,PubMed,10.1094/MPMI-01-13-0005-R,,p.spanu@imperial.ac.uk,no comments,C Pliego 2013,2013,,Pliego-2013-Host-induced gene si,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3955,PHI:2898,UniProt,N1JJX4,EMBL,CCU83226,,,,BEC1011,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei strain CH4.8,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23441578,PubMed,10.1094/MPMI-01-13-0005-R,,p.spanu@imperial.ac.uk,no comments,C Pliego 2013,2013,,Pliego-2013-Host-induced gene si,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3956,PHI:2899,UniProt,N1JFE2,EMBL,CCU76597,,,,BEC1038,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei strain CH4.8,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23441578,PubMed,10.1094/MPMI-01-13-0005-R,,p.spanu@imperial.ac.uk,no comments,C Pliego 2013,2013,,Pliego-2013-Host-induced gene si,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3957,PHI:2900,UniProt,N1JJE7,EMBL,CCU83284,,,,BEC1016,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei strain CH4.8,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23441578,PubMed,10.1094/MPMI-01-13-0005-R,,p.spanu@imperial.ac.uk,no comments,C Pliego 2013,2013,,Pliego-2013-Host-induced gene si,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3958,PHI:2901,UniProt,N1JK93,EMBL,CCU82707,,,,BEC1040,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei strain CH4.8,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23441578,PubMed,10.1094/MPMI-01-13-0005-R,,p.spanu@imperial.ac.uk,no comments,C Pliego 2013,2013,,Pliego-2013-Host-induced gene si,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3959,PHI:2902,UniProt,N1JN67,EMBL,CCU82095,,,,BEC1018,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei strain CH4.8,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23441578,PubMed,10.1094/MPMI-01-13-0005-R,,p.spanu@imperial.ac.uk,no comments,C Pliego 2013,2013,,Pliego-2013-Host-induced gene si,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3960,PHI:2903,UniProt,N1JJ94,EMBL,CCU83233,,,,BEC1054,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei strain CH4.8,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23441578,PubMed,10.1094/MPMI-01-13-0005-R,,p.spanu@imperial.ac.uk,no comments,C Pliego 2013,2013,,Pliego-2013-Host-induced gene si,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3961,PHI:2904,UniProt,M1T205,GenBank,JX134488,,,,Me10,,,,,,,13131,Macrosiphum euphorbiae,,,,eudicots,4100,Nicotiana benthamiana (no common name found),cv. NC-95,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23194342,PubMed,10.1094/MPMI-06-12-0144-FI,,Isgouhi.kaloshian@ucr.edu,Agrobacterium tumefaciens GV3101,H S Atamian 2013,2013,2 genes,Atamian-2013-In planta expression,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3962,PHI:2905,UniProt,M1T210,GenBank,JX134493,,,,Me23,,,,,,,13131,Macrosiphum euphorbiae,,,,eudicots,4100,Nicotiana benthamiana (no common name found),cv. NC-95,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23194342,PubMed,10.1094/MPMI-06-12-0144-FI,,Isgouhi.kaloshian@ucr.edu,Agrobacterium tumefaciens GV3101,H S Atamian 2013,2013,,Atamian-2013-In planta expression,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3963,PHI:2904,UniProt,M1T205,GenBank,JX134488,,,,Me10,,,,,,,13131,Macrosiphum euphorbiae,,,,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23194342,PubMed,10.1094/MPMI-06-12-0144-FI,,Isgouhi.kaloshian@ucr.edu,Agrobacterium tumefaciens GV3101,H S Atamian 2013,2013,,Atamian-2013-In planta expression,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3964,PHI:2904,UniProt,M1T205,GenBank,JX134488,,,,Me10,,,,,,,13131,Macrosiphum euphorbiae,,,,eudicots,4081,Solanum lycopersicum (related: tomato),cv. UC82b,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23194342,PubMed,10.1094/MPMI-06-12-0144-FI,,Isgouhi.kaloshian@ucr.edu,Agrobacterium tumefaciens GV3101,H S Atamian 2013,2013,,Atamian-2013-In planta expression,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3965,PHI:2906,UniProt,D4HUY5,GenBank,CBA19258,,,CFBP1430,rpoN,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; fruit,"sigma factor, regulating essential virulence gene expression",,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23721085,PubMed,10.1111/mpp.12045,,twm4@psu.edu,no comments,L S RAMOS 2013,2013,1 gene,Ramos-2013-The fire blight path,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3966,PHI:2906,UniProt,D4HUY5,GenBank,CBA19258,,,CFBP1430,rpoN,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf; fruit,"sigma factor, regulating essential virulence gene expression",,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23721085,PubMed,10.1111/mpp.12045,,twm4@psu.edu,no comments,L S RAMOS 2013,2013,,Ramos-2013-The fire blight path,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3967,PHI:2907,UniProt,I6YDU0,GenBank,FGSG_04092,,,PH-1,Cyp51A,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,Multi genes,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3968,PHI:2908,UniProt,I1RBR4,GenBank,FGSG_01000,,,PH-1,Cyp51B,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3969,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3970,PHI:2907,UniProt,I6YDU0,GenBank,FGSG_04092,,,PH-1,Cyp51A,,,,,,PHI:2909,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3971,PHI:2908,UniProt,I1RBR4,GenBank,FGSG_01000,,,PH-1,Cyp51B,,,,,,PHI:2909,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,reduced virulence,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3972,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,PHI:2907,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3973,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,PHI:2908,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,reduced virulence,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3974,PHI:2907,UniProt,I6YDU0,GenBank,FGSG_04092,,,PH-1,Cyp51A,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Landsberg erecta,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3975,PHI:2908,UniProt,I1RBR4,GenBank,FGSG_01000,,,PH-1,Cyp51B,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Landsberg erecta,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3976,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Landsberg erecta,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3977,PHI:2907,UniProt,I6YDU0,GenBank,FGSG_04092,,,PH-1,Cyp51A,,,,,,PHI:2909,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Landsberg erecta,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3978,PHI:2908,UniProt,I1RBR4,GenBank,FGSG_01000,,,PH-1,Cyp51B,,,,,,PHI:2909,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Landsberg erecta,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,reduced virulence,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3979,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,PHI:2907,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Landsberg erecta,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3980,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,PHI:2908,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Landsberg erecta,,,spikelet,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,reduced virulence,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3981,PHI:2907,UniProt,I6YDU0,GenBank,FGSG_04092,,,PH-1,Cyp51A,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Encore,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3982,PHI:2908,UniProt,I1RBR4,GenBank,FGSG_01000,,,PH-1,Cyp51B,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Encore,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3983,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Encore,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3984,PHI:2907,UniProt,I6YDU0,GenBank,FGSG_04092,,,PH-1,Cyp51A,,,,,,PHI:2909,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Encore,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3985,PHI:2908,UniProt,I1RBR4,GenBank,FGSG_01000,,,PH-1,Cyp51B,,,,,,PHI:2909,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Encore,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3986,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,PHI:2907,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Encore,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3987,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,PHI:2908,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Encore,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3988,PHI:2907,UniProt,I6YDU0,GenBank,FGSG_04092,,,PH-1,Cyp51A,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3750,Malus domestica (related: apple),cv. Braeburn,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3989,PHI:2908,UniProt,I1RBR4,GenBank,FGSG_01000,,,PH-1,Cyp51B,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3750,Malus domestica (related: apple),cv. Braeburn,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3990,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3750,Malus domestica (related: apple),cv. Braeburn,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3991,PHI:2907,UniProt,I6YDU0,GenBank,FGSG_04092,,,PH-1,Cyp51A,,,,,,PHI:2909,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3750,Malus domestica (related: apple),cv. Braeburn,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3992,PHI:2908,UniProt,I1RBR4,GenBank,FGSG_01000,,,PH-1,Cyp51B,,,,,,PHI:2909,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3750,Malus domestica (related: apple),cv. Braeburn,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3993,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,PHI:2907,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3750,Malus domestica (related: apple),cv. Braeburn,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3994,PHI:2909,UniProt,I1S2M5,EMBL,FGSG_11024,,,PH-1,Cyp51C,,,,,,PHI:2908,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3750,Malus domestica (related: apple),cv. Braeburn,,,fruit,"P450 sterol 14a-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides",,,sterol biosynthesis pathway,unaffected pathogenicity,,,,,,reduced,,wild type,reduced,no,tebuconazole; epoxiconazole; propiconazole; imazalil; metconazole; prochloraz; difenoconazole,propiconazole: CHEBI:8489,,,,,gene deletion: full,,,RP,23442154,PubMed,10.1111/nph.12193,,hans.cools@rothamsted.ac.uk,"Sensitivity to group 1, which includes tebuconazole, epoxiconazole, propiconazole and imazalil, is only affected significantly by FgCYP51A deletion'/ Deletions of both FgCYP51A and FgCYP51B increased the sensitivity to Group 2 compunds which include metconazole, prochloraz and difenoconazole",J Fan 2013,2013,,Fan-2013-Characterization of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3995,PHI:2910,UniProt,A7F519,GenBank,EDN97840,,,1980,Shk1,,,,,,,5180,Sclerotinia sclerotiorum,,HA61,,eudicots,3708,Brassica napus (related: rape),,,,leaf,two-component histidine kinase,,,HOG pathway,unaffected pathogenicity,,,,,,reduced,,reduced,,no,fludioxonil; iprodione; dimetachlone; benzimidazole; carbendazim; NaCl; KCl; glucose; D-sorbitol; H2O2,"iprodione: CHEBI:28909, CAS:36734-19-7; benzimidazole: CHEBI:36622; carbendazim: CHEBI:3392, CAS:10605-21-7; NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240",,,,,gene deletion: full; gene complementation,,,RP,23724858,PubMed,10.1111/mpp.12041,,mgzhou@njau.edu.cn,Disruption of Shk1 resulted in resistance to phenylpyrrole and dicarboximide fungi-cides and increased sensitivity to hyperosmotic stress and H2O2-induced oxidative stress,Y DUAN 2013,2013,1 gene,Duan-2013-A two-component hist,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3996,PHI:2910,UniProt,A7F519,GenBank,EDN97840,,,1980,Shk1,,,,,,,5180,Sclerotinia sclerotiorum,,HA61,,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,two-component histidine kinase,,,HOG pathway,unaffected pathogenicity,,,,,,reduced,,reduced,,no,fludioxonil; iprodione; dimetachlone; benzimidazole; carbendazim; NaCl; KCl; glucose; D-sorbitol; H2O2,"iprodione: CHEBI:28909, CAS:36734-19-7; benzimidazole: CHEBI:36622; carbendazim: CHEBI:3392, CAS:10605-21-7; NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240",,,,,gene deletion: full; gene complementation,,,RP,23724858,PubMed,10.1111/mpp.12041,,mgzhou@njau.edu.cn,Disruption of Shk1 resulted in resistance to phenylpyrrole and dicarboximide fungi-cides and increased sensitivity to hyperosmotic stress and H2O2-induced oxidative stress,Y DUAN 2013,2013,,Duan-2013-A two-component hist,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3997,PHI:2910,UniProt,A7F519,GenBank,EDN97840,,,1980,Shk1,,,,,,,5180,Sclerotinia sclerotiorum,,HA61,,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,two-component histidine kinase,,,HOG pathway,unaffected pathogenicity,,,,,,reduced,,reduced,,no,fludioxonil; iprodione; dimetachlone; benzimidazole; carbendazim; NaCl; KCl; glucose; D-sorbitol; H2O2,"iprodione: CHEBI:28909, CAS:36734-19-7; benzimidazole: CHEBI:36622; carbendazim: CHEBI:3392, CAS:10605-21-7; NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240",,,,,gene deletion: full; gene complementation,,,RP,23724858,PubMed,10.1111/mpp.12041,,mgzhou@njau.edu.cn,Disruption of Shk1 resulted in resistance to phenylpyrrole and dicarboximide fungi-cides and increased sensitivity to hyperosmotic stress and H2O2-induced oxidative stress,Y DUAN 2013,2013,,Duan-2013-A two-component hist,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3998,PHI:2910,UniProt,A7F519,GenBank,EDN97840,,,1980,Shk1,,,,,,,5180,Sclerotinia sclerotiorum,,HA61,,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,two-component histidine kinase,,,HOG pathway,unaffected pathogenicity,,,,,,reduced,,reduced,,no,fludioxonil; iprodione; dimetachlone; benzimidazole; carbendazim; NaCl; KCl; glucose; D-sorbitol; H2O2,"iprodione: CHEBI:28909, CAS:36734-19-7; benzimidazole: CHEBI:36622; carbendazim: CHEBI:3392, CAS:10605-21-7; NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240",,,,,gene deletion: full; gene complementation,,,RP,23724858,PubMed,10.1111/mpp.12041,,mgzhou@njau.edu.cn,Disruption of Shk1 resulted in resistance to phenylpyrrole and dicarboximide fungi-cides and increased sensitivity to hyperosmotic stress and H2O2-induced oxidative stress,Y DUAN 2013,2013,,Duan-2013-A two-component hist,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 3999,PHI:2911,UniProt,A7F6V9,GenBank,XP_001585822,,,1980,Ss-pth2,,,,,,,5180,Sclerotinia sclerotiorum,,274,,eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf,peroxysomal carnitine acetyl transferase,,,,reduced virulence,,yes,no,yes,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,23581822,PubMed,10.1094/MPMI-03-13-0075-R,,katherine.dobinson@agr.gc.ca,"Null mutants failed to grow on MM amended with glycerol, potassium acetate, oleic acid, or glycerol as sole carbon sources",D Liberti 2013,2013,1 gene,Liberti-2013-Peroxysomal Carnitin,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4000,PHI:2912,UniProt,H9AWW9,GenBank,JN900389,,,,AaNoxA,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,NADPH oxidase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2; cumyl H2O2; rose bengal (RB); diamide; menadione; KO2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261; menadione: CHEBI:28869,,,,,gene disruption; gene complementation,,,RP,23527595,PubMed,10.1111/mpp.12026,,krchung@ufl.edu,Nox contributes to oxidative stress resistance,S L YANG 2013,2013,Multi genes,Yang-2013-Similar and distinct,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4001,PHI:2913,UniProt,J7H173,GenBank,AFP89626,,,EV-MIL31,AaNoxB,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,NADPH oxidase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2; cumyl H2O2; rose bengal (RB); diamide; menadione; KO2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261; menadione: CHEBI:28869,,,,,gene disruption; gene complementation,,,RP,23527595,PubMed,10.1111/mpp.12026,,krchung@ufl.edu,Nox contributes to oxidative stress resistance,S L YANG 2013,2013,,Yang-2013-Similar and distinct,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4002,PHI:2914,UniProt,J7H6V8,GenBank,JX207117,,,EV-MIL31,AaNoxR,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,NADPH oxidase,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,H2O2; cumyl H2O2; rose bengal (RB); diamide; menadione; KO2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261; menadione: CHEBI:28869,,,,,gene disruption; gene complementation,,,RP,23527595,PubMed,10.1111/mpp.12026,,krchung@ufl.edu,Nox contributes to oxidative stress resistance,S L YANG 2013,2013,,Yang-2013-Similar and distinct,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4003,PHI:2912,UniProt,H9AWW9,GenBank,JN900389,,,,AaNoxA,,,,,,PHI:2913,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,NADPH oxidase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2; cumyl H2O2; rose bengal (RB); diamide; menadione; KO2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261; menadione: CHEBI:28869,,,,,gene disruption; gene complementation,,,RP,23527595,PubMed,10.1111/mpp.12026,,krchung@ufl.edu,Nox contributes to oxidative stress resistance,S L YANG 2013,2013,,Yang-2013-Similar and distinct,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4004,PHI:2913,UniProt,J7H173,GenBank,AFP89626,,,EV-MIL31,AaNoxB,,,,,,PHI:2912,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,NADPH oxidase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2; cumyl H2O2; rose bengal (RB); diamide; menadione; KO2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261; menadione: CHEBI:28869,,,,,gene disruption; gene complementation,,,RP,23527595,PubMed,10.1111/mpp.12026,,krchung@ufl.edu,Nox contributes to oxidative stress resistance,S L YANG 2013,2013,,Yang-2013-Similar and distinct,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4005,PHI:2912,UniProt,H9AWW9,GenBank,JN900389,,,,AaNoxA,,,,,,PHI:2914,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,NADPH oxidase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2; cumyl H2O2; rose bengal (RB); diamide; menadione; KO2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261; menadione: CHEBI:28869,,,,,gene disruption; gene complementation,,,RP,23527595,PubMed,10.1111/mpp.12026,,krchung@ufl.edu,Nox contributes to oxidative stress resistance,S L YANG 2013,2013,,Yang-2013-Similar and distinct,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4006,PHI:2914,UniProt,J7H6V8,GenBank,JX207117,,,EV-MIL31,AaNoxR,,,,,,PHI:2912,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,NADPH oxidase,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,H2O2; cumyl H2O2; rose bengal (RB); diamide; menadione; KO2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261; menadione: CHEBI:28869,,,,,gene disruption; gene complementation,,,RP,23527595,PubMed,10.1111/mpp.12026,,krchung@ufl.edu,Nox contributes to oxidative stress resistance,S L YANG 2013,2013,,Yang-2013-Similar and distinct,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4007,PHI:2915,,no data found,FCGP,FVEG_01508,,,,Ppr1,,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. B73,,,kernel,protein phosphatase 2A regulatory subunit,,,,unaffected pathogenicity,no,,,,,increased,wild type,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,23452277,PubMed,10.1111/mpp.12023,,wbshim@tamu.edu,no comments,J SHIN 2013,2013,2 genes,Shin-2013-Protein phosphatase,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4008,PHI:2916,UniProt,W7M5P0,FCGP,FVEG_04543,,,,Ppr2,,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. B73,,,kernel,protein phosphatase 2A regulatory subunit,,,,unaffected pathogenicity,no,,,,,reduced,wild type,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,23452277,PubMed,10.1111/mpp.12023,,wbshim@tamu.edu,no comments,J SHIN 2013,2013,,Shin-2013-Protein phosphatase,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4009,PHI:2917,,no data found,JGI,188986,,,,CfTom1,,,,,,,5499,Fulvia fulva,,race 0WU,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,GH10 tomatinase,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,23448507,PubMed,10.1111/nph.12208,,pierre.dewit@wur.nl,no comments,Okmen et al.,2013,1 gene,Okmen-2013-Detoxification of al,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4010,PHI:2918,UniProt,Q4UV56,GenBank,AAY49067,,,8004,AvrXccC,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling; leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23252460,PubMed,10.1094/MPMI-06-12-0164-R,,jyang@nchu.edu.tw,A. tumefaciens strain ABI or EHA105,Y Ho 2013,2013,1 gene,Ho-2013-The AvrB_AvrC domain,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4011,PHI:2919,UniProt,E4ZT84,GenBank,CBX90026,,,JN3,AvrLm11,microchromosome,,,,,,5022,Leptosphaeria maculans,,IBCN 14,stem canker,eudicots,3708,Brassica napus (related: rape),Z1 line,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23406519,PubMed,10.1111/nph.12178,,mhb@versailles.inra.fr,A. tumefaciens strain C58,M Balesdent 2013,2013,1 gene,Balesdent-2013-The dispensable chro,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4012,PHI:2920,UniProt,E3QRA4,GenBank,EFQ33392.,,,M1.001,FET3-1,,,,,,,31870,Colletotrichum graminicola,,CgM2,anthracnose (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Nathan,,,leaf,functional ferroxidase,,,,reduced virulence,,yes,yes,,,,,wild type,reduced,no,rose bengal; H2O2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261,,,,,gene deletion: full,,,RP,23639025,PubMed,10.1094/MPMI-01-13-0003-R,,holger.deising@landw.uni-halle.de,no comments,E Albarouki 2013,2013,2 genes,Albarouki-2013-Infection Structure-,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4013,PHI:2921,UniProt,E3Q7G1,GenBank,EFQ26799.1,,,M1.001,FET3-2,,,,,,,31870,Colletotrichum graminicola,,CgM2,anthracnose (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Nathan,,,leaf,functional ferroxidase,,,,reduced virulence,,yes,yes,,,,,wild type,wild type,no,rose bengal; H2O2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261,,,,,gene deletion: full,,,RP,23639025,PubMed,10.1094/MPMI-01-13-0003-R,,holger.deising@landw.uni-halle.de,no comments,E Albarouki 2013,2013,,Albarouki-2013-Infection Structure-,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4014,PHI:2920,UniProt,E3QRA4,GenBank,EFQ33392.,,,M1.001,FET3-1,,,,,,PHI:2921,31870,Colletotrichum graminicola,,CgM2,anthracnose (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Nathan,,,leaf,functional ferroxidase,,,,reduced virulence,,yes,yes,,,,,wild type,reduced,no,rose bengal; H2O2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261,,,,,gene deletion: full,,,RP,23639025,PubMed,10.1094/MPMI-01-13-0003-R,,holger.deising@landw.uni-halle.de,no comments,E Albarouki 2013,2013,,Albarouki-2013-Infection Structure-,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4015,PHI:2921,UniProt,E3Q7G1,GenBank,EFQ26799.1,,,M1.001,FET3-2,,,,,,PHI:2920,31870,Colletotrichum graminicola,,CgM2,anthracnose (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Nathan,,,leaf,functional ferroxidase,,,,reduced virulence,,yes,yes,,,,,wild type,reduced,no,rose bengal; H2O2,H2O2: CHEBI:16240; rose bengal: CHEBI:52261,,,,,gene deletion: full,,,RP,23639025,PubMed,10.1094/MPMI-01-13-0003-R,,holger.deising@landw.uni-halle.de,no comments,E Albarouki 2013,2013,,Albarouki-2013-Infection Structure-,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4016,PHI:2922,UniProt,Q8XYE3,,,,,,Brg11,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,TAL effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23692030,PubMed,10.1111/nph.12324,,lahaye@bio.lmu.de,Agrobacterium tumefaciens GV3101,O de Lange 2013,2013,1 gene,de Lange-2013-Breaking the DNA-bin,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4017,PHI:2923,UniProt,I6YWH2,GenBank,JQ973666,,,EV-MIL31,AaNPS6,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),,,,leaf,nonribosomal peptide synthetase,,,,reduced virulence,,yes,yes,,,reduced,,aberrant,,no,"rose bengal; H2O2; cumyl H2O2; menadione; t -butyl H2O2; KO2 ; bathophenanthroline disulphonic acid; 2,2 ′-dipyridyl; sodium nitroprusside; hydroxylamine-HCl","menadione: CHEBI:28869; H2O2: CHEBI:16240; rose bengal: CHEBI:52261; t -butyl H2O2: CHEBI:64090; 2,2'-bipyridine: CHEBI:30351; sodium nitroprusside: CHEBI:29321",,,,,gene deletion: full; gene complementation,,,RP,23438010,PubMed,10.1111/mpp.12021,,krchung@ufl.edu,"Elevated sensitivity to H2O2, seen for the Dnps6 null strain could be relieved by exogenous application of ferric iron. Mutants were more sensitive supersuperoxide-generating compounds, also to the iron chelator bathophenanthroline disulphonic acid (BPTS at 200 m M), but not to a second iron chelator 2,2 ′-dipyridyl (2DP at 300 mM). On MM, the nitric oxide-generating compounds sodium nitroprusside (at 1 m M) and hydroxylamine-HCl (at 5m M)reduced the radial growth of D nps6 mutants",L CHEN 2013,2013,1 gene,Chen-2013-A nonribosomal pepti,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4018,PHI:2924,UniProt,J9MXG1,GenBank,EF613329,,,,lip1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,lipases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23718123,PubMed,10.1094/MPMI-03-13-0082-R,,roncero@uco.es,no comments,G B Ruiz 2013,2013,Multi genes,Bravo Ruiz-2013-Lipolytic system of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4019,PHI:2925,UniProt,J9MBA2,,,,,,lip2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,lipases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23718123,PubMed,10.1094/MPMI-03-13-0082-R,,roncero@uco.es,no comments,G B Ruiz 2013,2013,,Bravo Ruiz-2013-Lipolytic system of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4020,PHI:2926,UniProt,J9NE50,,,,,,lip3,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,lipases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23718123,PubMed,10.1094/MPMI-03-13-0082-R,,roncero@uco.es,no comments,G B Ruiz 2013,2013,,Bravo Ruiz-2013-Lipolytic system of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4021,PHI:2927,UniProt,J9N2Z8,,,,,,lip5,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,lipases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23718123,PubMed,10.1094/MPMI-03-13-0082-R,,roncero@uco.es,no comments,G B Ruiz 2013,2013,,Bravo Ruiz-2013-Lipolytic system of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4022,PHI:2928,UniProt,J9NNZ8,,,,,,lip22,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,lipases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23718123,PubMed,10.1094/MPMI-03-13-0082-R,,roncero@uco.es,no comments,G B Ruiz 2013,2013,,Bravo Ruiz-2013-Lipolytic system of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4023,PHI:2929,UniProt,J9MMS5,GenBank,EF613328,,,,ctf1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,lipases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23718123,PubMed,10.1094/MPMI-03-13-0082-R,,roncero@uco.es,"deltactf1, deltactf2 and deltactf1deltactf2 mutants showed growth defects in the 2 presence of fatty acids",G B Ruiz 2013,2013,,Bravo Ruiz-2013-Lipolytic system of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4024,PHI:2930,UniProt,J9MFF7,,,,,,ctf2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,lipases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23718123,PubMed,10.1094/MPMI-03-13-0082-R,,roncero@uco.es,"deltactf1, deltactf2 and deltactf1deltactf2 mutants showed growth defects in the 2 presence of fatty acids",G B Ruiz 2013,2013,,Bravo Ruiz-2013-Lipolytic system of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4025,PHI:2929,UniProt,J9MMS5,GenBank,EF613328,,,,ctf1,,,,,,PHI:2930,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,lipases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23718123,PubMed,10.1094/MPMI-03-13-0082-R,,roncero@uco.es,"deltactf1, deltactf2 and deltactf1deltactf2 mutants showed growth defects in the 2 presence of fatty acids",G B Ruiz 2013,2013,,Bravo Ruiz-2013-Lipolytic system of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4026,PHI:2930,UniProt,J9MFF7,,,,,,ctf2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,root,lipases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23718123,PubMed,10.1094/MPMI-03-13-0082-R,,roncero@uco.es,"deltactf1, deltactf2 and deltactf1deltactf2 mutants showed growth defects in the 2 presence of fatty acids",G B Ruiz 2013,2013,,Bravo Ruiz-2013-Lipolytic system of,Batch029,2013-06-01,MC,,,,,,,,,,,,,
,,Record 4027,PHI:2931,UniProt,Q6ZXG2,GenBank,CAG27601,,,NCPPB 2293,DspA/E,,,,,,,552,Erwinia amylovora,,,fire blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf; seedling,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23634775,PubMed,10.1111/mpp.12022,,mathilde.fagard@versailles.inra.fr,Agrobacterium sp. strain C58C1,A DEGRAVE 2013,2013,1 gene,Degrave-2013-The bacterial effect,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4028,PHI:2932,UniProt,F8WSC5,GenBank,BAK52527,,,,NoxA,,,,,,,5599,Alternaria alternata,,15A,brown spot,eudicots,23211,Pyrus communis (related: pear),cv. Nijisseiki,,,leaf,NADPH oxidase,,,,unaffected pathogenicity,,no,no,no,,increased,,reduced; aberrant,,no,,,,,,,gene disruption,,,RP,23279187,PubMed,10.1111/mpp.12013,,ikeken@phoenix.kobe-u.ac.jp,no comments,Y MORITA 2013,2013,2 genes,Morita-2013-Appressorium-localiz,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4029,PHI:2933,UniProt,J7H173,GenBank,AFP89626,,,EV-MIL 31,NoxB,,,,,,,5599,Alternaria alternata,,15A,brown spot,eudicots,23211,Pyrus communis (related: pear),cv. Nijisseiki,,,leaf,NADPH oxidase,,,,loss of pathogenicity,,no,yes,yes,,increased,,reduced; aberrant,,no,,,,,,,gene disruption,,,RP,23279187,PubMed,10.1111/mpp.12013,,ikeken@phoenix.kobe-u.ac.jp,no comments,Y MORITA 2013,2013,,Morita-2013-Appressorium-localiz,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4030,PHI:2932,UniProt,F8WSC5,GenBank,BAK52527,,,,NoxA,,,,,,PHI:2933,5599,Alternaria alternata,,15A,brown spot,eudicots,23211,Pyrus communis (related: pear),cv. Nijisseiki,,,leaf,NADPH oxidase,,,,loss of pathogenicity,,no,yes,yes,,increased,,reduced; aberrant,,no,,,,,,,gene disruption,,,RP,23279187,PubMed,10.1111/mpp.12013,,ikeken@phoenix.kobe-u.ac.jp,no comments,Y MORITA 2013,2013,,Morita-2013-Appressorium-localiz,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4031,PHI:2933,UniProt,J7H173,GenBank,AFP89626,,,EV-MIL 31,NoxB,,,,,,PHI:2932,5599,Alternaria alternata,,15A,brown spot,eudicots,23211,Pyrus communis (related: pear),cv. Nijisseiki,,,leaf,NADPH oxidase,,,,loss of pathogenicity,,no,yes,yes,,increased,,reduced; aberrant,,no,,,,,,,gene disruption,,,RP,23279187,PubMed,10.1111/mpp.12013,,ikeken@phoenix.kobe-u.ac.jp,no comments,Y MORITA 2013,2013,,Morita-2013-Appressorium-localiz,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4032,PHI:2934,UniProt,A0A024CIG8,,,,,,cifA,,,,,,PHI:2935,36746,Pseudomonas cichorii,,SF1-54,midrib rot (lettuce),eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Flandria,,,leaf,nonribosomal peptide synthethase-encoding gene responsible for cichofactin biosynthesis,,,,reduced virulence,,no,yes,,,,,,,no,,,,,,,gene deletion: full,,,RP,23405865,PubMed,10.1094/MPMI-11-12-0258-R,,monica.hofte@ugent.be,no comments,E Pauwelyn 2013,2013,2 genes,Pauwelyn-2013-New linear lipopepti,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4033,PHI:2935,UniProt,A0A024CHY2,,,,,,cifB,,,,,,PHI:2934,36746,Pseudomonas cichorii,,SF1-54,midrib rot (lettuce),eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Flandria,,,leaf,nonribosomal peptide synthethase-encoding gene responsible for cichofactin biosynthesis,,,,reduced virulence,,no,yes,,,,,,,no,,,,,,,gene deletion: full,,,RP,23405865,PubMed,10.1094/MPMI-11-12-0258-R,,monica.hofte@ugent.be,no comments,E Pauwelyn 2013,2013,,Pauwelyn-2013-New linear lipopepti,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4034,PHI:2936,UniProt,Q87BR6,GenBank,AAO29229,,,Temecula1,XhpT,,,,,,,2371,Xylella fastidiosa,,Fetzer,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem; petiole,"response regulator involved in surface attachment, cell-cell aggregation, exopolysaccharide production and virulence",,,,reduced virulence,,,,no,,,,aberrant,,no,,,,,,,gene disruption,,,RP,23186359,PubMed,10.1111/mpp.12004,,mcroper@ucr.edu,no comments,T M VOEGEL 2013,2013,1 gene,Voegel-2013-Identification of a,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4035,PHI:2937,UniProt,Q87BQ4,GenBank,AAO29241,,,Temecula1,gumD,,,,,,,2371,Xylella fastidiosa,183190,Temecula,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Cabernet Sauvignon,,,stem; petiole,,,,,loss of pathogenicity,,yes,,yes,,,,aberrant; increased,,no,,,,,,,gene disruption,,,RP,23678891,PubMed,10.1094/MPMI-09-12-0211-R,,nabilkilliny@ufl.edu,no comments,N Killiny 2013,2013,2 genes,Killiny-2013-The Exopolysaccharid,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4036,PHI:2938,UniProt,Q87BQ7,GenBank,AAO29238,,,Temecula1,gumH,,,,,,,2371,Xylella fastidiosa,183190,Temecula,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Cabernet Sauvignon,,,stem; petiole,,,,,loss of pathogenicity,,yes,,yes,,,,aberrant; increased,,no,,,,,,,gene disruption,,,RP,23678891,PubMed,10.1094/MPMI-09-12-0211-R,,nabilkilliny@ufl.edu,no comments,N Killiny 2013,2013,,Killiny-2013-The Exopolysaccharid,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4037,PHI:2939,UniProt,Q0VHC3,GenBank,ABH07404,,,RS105,HrpE3,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,type III effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23672717,PubMed,10.1111/mpp.12039,,gyouchen@sjtu.edu.cn,no comments,Y CUI 2013,2013,1 gene,Cui-2013-HrpE3 is a type III,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4038,PHI:2940,UniProt,G4MV67,GenBank,EHA54082,,,70-15,MoARK1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,actin-regulating kinase homologue,,,,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,NaCl; KCl; sorbitol,sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene disruption; gene complementation,,,RP,23384308,PubMed,10.1111/mpp.12020,,zhgzhang@njau.edu.cn,Mutants were hyposensitive to exogenous oxidative and osmotic stress,J WANG 2013,2013,1 gene,Wang-2013-The actin-regulating,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4039,PHI:2941,UniProt,L7WWG5,GenBank,KC004057,,,P6497,Avr1d,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf,avirulence gene,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23550527,PubMed,10.1094/MPMI-02-13-0036-R,,mark.gijzen@agr.gc.ca,no comments,R Na 2013,2013,1 gene,Na-2013-Deletion of the Phyt,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4040,PHI:2941,UniProt,L7WWG5,GenBank,KC004057,,,P6497,Avr1d,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Haro 16,,,leaf,avirulence gene,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23550527,PubMed,10.1094/MPMI-02-13-0036-R,,mark.gijzen@agr.gc.ca,no comments,R Na 2013,2013,,Na-2013-Deletion of the Phyt,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4041,PHI:2942,,no data found,GenBank,FK937603,,,310,PSE1,,,,,,,4792,Phytophthora nicotianae,,310,buckeye rot (potato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,RXLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23594295,PubMed,10.1111/nph.12270,,mathieu.gourgues@sophia.inra.fr,Agrobacterium tumefaciens strain GV3301. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',E Evangelisti 2013,2013,1 gene,Evangelisti-2013-The Phytophthora par,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4042,PHI:2943,UniProt,L7WWG5,GenBank,KC004057,,,P6497,Avr1d,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Haro 16,,,leaf,avirulence gene,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23594349,PubMed,10.1094/MPMI-02-13-0035-R,,wangyc@njau.edu.cn,A. tumefaciens strain GV3101,W Yin 2013,2013,1 gene,Yin-2013-Phytophthora sojae A,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4043,PHI:2943,UniProt,L7WWG5,GenBank,KC004057,,,P6497,Avr1d,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,avirulence gene,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23594349,PubMed,10.1094/MPMI-02-13-0035-R,,wangyc@njau.edu.cn,A. tumefaciens strain GV3101,W Yin 2013,2013,,Yin-2013-Phytophthora sojae A,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4044,PHI:2944,UniProt,G3C9T8,GenBank,CCC55864,,,Emoy2,HaRxLL464,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23734779,PubMed,10.1094/MPMI-06-12-0154-R,,jonathan.jones@sainsbury-laboratory.ac.uk,A. tumefaciens strain GV3101,J L Badel 2013,2013,Multi genes,Badel-2013-In Planta Effector C,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4045,PHI:2945,UniProt,G3C9Q9,GenBank,CCC55835,,,Emoy2,HaRxL75,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23734779,PubMed,10.1094/MPMI-06-12-0154-R,,jonathan.jones@sainsbury-laboratory.ac.uk,A. tumefaciens strain GV3101,J L Badel 2013,2013,,Badel-2013-In Planta Effector C,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4046,PHI:2946,UniProt,G3C9N8,GenBank,CCC55814,,,Emoy2,HaRxL22,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23734779,PubMed,10.1094/MPMI-06-12-0154-R,,jonathan.jones@sainsbury-laboratory.ac.uk,A. tumefaciens strain GV3101,J L Badel 2013,2013,,Badel-2013-In Planta Effector C,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4047,PHI:2947,UniProt,G3C9T3,GenBank,CCC55859,,,Emoy2,HaRxLL441,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23734779,PubMed,10.1094/MPMI-06-12-0154-R,,jonathan.jones@sainsbury-laboratory.ac.uk,A. tumefaciens strain GV3101,J L Badel 2013,2013,,Badel-2013-In Planta Effector C,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4048,PHI:2948,UniProt,G3C9R3,GenBank,CCC55839,,,Emoy2,HaRxL89,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,23734779,PubMed,10.1094/MPMI-06-12-0154-R,,jonathan.jones@sainsbury-laboratory.ac.uk,A. tumefaciens strain GV3101,J L Badel 2013,2013,,Badel-2013-In Planta Effector C,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4049,PHI:2949,UniProt,I0ISN4,GenBank,AB674327,,,6605,vfr,,,,,,,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,wildfire disease,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,virulence factor regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,23145783,PubMed,10.1111/mpp.12003,,yuki@cc.okayama-u.ac.j,no comments,F TAGUCHI 2013,2013,2 genes,Taguchi-2013-Virulence factor reg,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4050,PHI:2950,UniProt,L8AYM6,GenBank,AB733003,,,6605,cyaA,,,,,,,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,wildfire disease,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,adenylate cyclase gene responsible for cAMP synthesis,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,23145783,PubMed,10.1111/mpp.12003,,yuki@cc.okayama-u.ac.j,no comments,F TAGUCHI 2013,2013,,Taguchi-2013-Virulence factor reg,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4051,PHI:2949,UniProt,I0ISN4,GenBank,AB674327,,,6605,vfr,,,,,,,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,wildfire disease,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,virulence factor regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,23145783,PubMed,10.1111/mpp.12003,,yuki@cc.okayama-u.ac.j,no comments,F TAGUCHI 2013,2013,,Taguchi-2013-Virulence factor reg,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4052,PHI:2950,UniProt,L8AYM6,GenBank,AB733003,,,6605,cyaA,,,,,,,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,wildfire disease,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,adenylate cyclase gene responsible for cAMP synthesis,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,23145783,PubMed,10.1111/mpp.12003,,yuki@cc.okayama-u.ac.j,no comments,F TAGUCHI 2013,2013,,Taguchi-2013-Virulence factor reg,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4053,PHI:2951,UniProt,K8Z7I4,GenBank,EKU26002,,,Xtg29,hrpE,,,,,,,343,Xanthomonas translucens,1195885,pv. graminis strain ART-Xtg29,bacterial wilt,monocots,4521,Lolium multiflorum (related: italian ryegrass),,,,leaf,gene belonging to the noncanonical type III secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,23578314,PubMed,10.1111/mpp.12030,,roland.koelliker@agroscope.admin.ch,no comments,F WICHMANN 2013,2013,Multi genes,Wichmann-2013-The noncanonical typ,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4054,PHI:2952,UniProt,K8Z4X7,GenBank,EKU26024,,,Xtg29,hrcR,,,,,,,343,Xanthomonas translucens,1195885,pv. graminis strain ART-Xtg29,bacterial wilt,monocots,4521,Lolium multiflorum (related: italian ryegrass),,,,leaf,gene belonging to the noncanonical type III secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,23578314,PubMed,10.1111/mpp.12030,,roland.koelliker@agroscope.admin.ch,no comments,F WICHMANN 2013,2013,,Wichmann-2013-The noncanonical typ,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4055,PHI:2953,UniProt,K8ZK72,GenBank,EKU26016,,,Xtg29,hrpG,,,,,,,343,Xanthomonas translucens,1195885,pv. graminis strain ART-Xtg29,bacterial wilt,monocots,4521,Lolium multiflorum (related: italian ryegrass),,,,leaf,gene belonging to the noncanonical type III secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,23578314,PubMed,10.1111/mpp.12030,,roland.koelliker@agroscope.admin.ch,no comments,F WICHMANN 2013,2013,,Wichmann-2013-The noncanonical typ,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4056,PHI:2952,UniProt,K8Z4X7,GenBank,EKU26024,,,Xtg29,hrcR,,,,,,PHI:2953,343,Xanthomonas translucens,1195885,pv. graminis strain ART-Xtg29,bacterial wilt,monocots,4521,Lolium multiflorum (related: italian ryegrass),,,,leaf,gene belonging to the noncanonical type III secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,23578314,PubMed,10.1111/mpp.12030,,roland.koelliker@agroscope.admin.ch,no comments,F WICHMANN 2013,2013,,Wichmann-2013-The noncanonical typ,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4057,PHI:2953,UniProt,K8ZK72,GenBank,EKU26016,,,Xtg29,hrpG,,,,,,PHI:2952,343,Xanthomonas translucens,1195885,pv. graminis strain ART-Xtg29,bacterial wilt,monocots,4521,Lolium multiflorum (related: italian ryegrass),,,,leaf,gene belonging to the noncanonical type III secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,23578314,PubMed,10.1111/mpp.12030,,roland.koelliker@agroscope.admin.ch,no comments,F WICHMANN 2013,2013,,Wichmann-2013-The noncanonical typ,Batch029,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4058,PHI:2954,UniProt,B6KLD2,GenBank,EEB01666,,,ME49,TgNST1,,,,,,,5811,Toxoplasma gondii,,PRY225,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,brain,nucleotide-sugar transporter,,,,reduced virulence,,no,,no,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23658519,PubMed,10.1371/journal.ppat.1003331,,john. boothroyd@stanfor d.edu,no comments,C E Caffaro 2013,2013,1 gene,Caffaro-2013-A nucleotide sugar t,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4059,PHI:2955,UniProt,J9VH94,GenBank,AFR93777,,,H99,PKH2-02,chromosome 3,,,,,,5207,Cryptococcus neoformans,178876,var. grubii strain CM018,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,phosphoinositide-dependent kinase 1,,,,loss of pathogenicity,,no,,no,,,,,,no,NaNO2; H2O2; OSU-03012; fluconazole; amphotericin B,H2O2: CHEBI:16240; amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,RP,23087368,PubMed,10.1128/EC.00235-12,,damian_krysan@urmc.rochester.edu,Mutants more sensitive to the fungicisides and oxidative and nitro stress,Y Chabrier-Rosello 2013,2013,1 gene,Chabrier-Rosello-2013-Cryptococcus neoform,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4060,PHI:2956,,no data found,,,,,,ipx41,,,,,,,305,Ralstonia solanacearum,1091042,K60,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,petiole,putative transmembrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,15341645,PubMed,10.1111/j.1365-2958.2004.04237.x,,cza@plantpath.wisc.edu,no comments,D G Brown,2004,2 genes,Brown-2004-Ralstonia solanacear,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4061,PHI:2957,,no data found,,,,,,ipx46,,,,,,,305,Ralstonia solanacearum,1091042,K60,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,petiole,putative transmembrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,15341645,PubMed,10.1111/j.1365-2958.2004.04237.x,,cza@plantpath.wisc.edu,no comments,D G Brown,2004,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4062,PHI:2958,UniProt,C5BG70,GenBank,ACR70033,,,93-146,sdhC,,,,,,,67780,Edwardsiella ictaluri,634503,93-146,enteric septicemia,bony fishes,7998,Ictalurus punctatus (related: channel catfish),,,,,succinate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,RP,23762452,PubMed,10.1371/journal.pone.0065973,,lawrence@cvm.msstate.edu,no comments,N Dahal 2013,2013,Multi genes,Dahal-2013-Tricarboxylic Acid C,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4063,PHI:2959,UniProt,C5BF98,GenBank,ACR67684,,,93-146,mdh,,,,,,,67780,Edwardsiella ictaluri,634503,93-146,enteric septicemia,bony fishes,7998,Ictalurus punctatus (related: channel catfish),,,,,malate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,RP,23762452,PubMed,10.1371/journal.pone.0065973,,lawrence@cvm.msstate.edu,no comments,N Dahal 2013,2013,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4064,PHI:2960,UniProt,C5BDL7,GenBank,ACR67633,,,93-146,frdA,,,,,,,67780,Edwardsiella ictaluri,634503,93-146,enteric septicemia,bony fishes,7998,Ictalurus punctatus (related: channel catfish),,,,,fumarate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,RP,23762452,PubMed,10.1371/journal.pone.0065973,,lawrence@cvm.msstate.edu,no comments,N Dahal 2013,2013,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4065,PHI:2961,UniProt,C5BAT0,GenBank,ACR70489,,,93-146,gcvP,,,,,,,67780,Edwardsiella ictaluri,634503,93-146,enteric septicemia,bony fishes,7998,Ictalurus punctatus (related: channel catfish),,,,,glycine dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,RP,23762452,PubMed,10.1371/journal.pone.0065973,,lawrence@cvm.msstate.edu,no comments,N Dahal 2013,2013,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4066,PHI:2962,UniProt,C5BEV2,GenBank,ACR70340,,,93-146,glyA,,,,,,,67780,Edwardsiella ictaluri,634503,93-146,enteric septicemia,bony fishes,7998,Ictalurus punctatus (related: channel catfish),,,,,serine hydroxymethyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,RP,23762452,PubMed,10.1371/journal.pone.0065973,,lawrence@cvm.msstate.edu,no comments,N Dahal 2013,2013,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4067,PHI:2963,UniProt,Q56935,GenBank,AAA86826,,,,YopK,,,,,,,633,Yersinia pseudotuberculosis,502800,YPIII/pIB102,gastrointestinal disease; yersiniosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,23090955,PubMed,10.1128/IAI.00650-12,,maria.fallman@molbiol.umu.se,no comments,S E Thorslund 2013,2013,1 gene,Thorslund-2013-Role of YopK in Yers,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4068,PHI:2964,UniProt,G7TM01,GenBank,AEQ97152,,,BLS256,AsnB,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,seedling; leaf,asparagine synthetase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,23157387,PubMed,10.1111/j.1364-3703.2012.00838.x,,fqliu20011@sina.com,Mutant was unable to grow in basic MMX (-) medium (a minimal medium without ammonium sulphate as the nitrogen source). / disruption of asnB impaired pathogen resistance to oxidative stress,G QIAN 2013,2013,1 gene,"Qian-2013-AsnB, regulated by d",Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4069,PHI:2965,UniProt,Q2FZ08,GenBank,BAF96735,,,,cvfA,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,moths,7091,Bombyx mori (related: domestic silkworm),,,,,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,15853881,PubMed,10.1111/j.1365-2958.2005.04596.x,,kurokawa@mol.f.u-tokyo.ac.jp,no comments,C Kaito 2005,2005,Multi genes,Kaito-2005-Silkworm pathogenic,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4070,PHI:2966,UniProt,Q2FYP3,GenBank,ABD30486,,,NCTC 8325,cvfB,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,moths,7091,Bombyx mori (related: domestic silkworm),,,,,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,15853881,PubMed,10.1111/j.1365-2958.2005.04596.x,,kurokawa@mol.f.u-tokyo.ac.jp,no comments,C Kaito 2005,2005,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4071,PHI:2967,UniProt,Q5HFZ4,GenBank,AAW36665,,,Col,cvfC,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,moths,7091,Bombyx mori (related: domestic silkworm),,,,,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,15853881,PubMed,10.1111/j.1365-2958.2005.04596.x,,kurokawa@mol.f.u-tokyo.ac.jp,no comments,C Kaito 2005,2005,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4072,PHI:2965,UniProt,Q2FZ08,GenBank,BAF96735,,,,cvfA,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,15853881,PubMed,10.1111/j.1365-2958.2005.04596.x,,kurokawa@mol.f.u-tokyo.ac.jp,no comments,C Kaito 2005,2005,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4073,PHI:2967,UniProt,Q5HFZ4,GenBank,AAW36665,,,Col,cvfC,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,15853881,PubMed,10.1111/j.1365-2958.2005.04596.x,,kurokawa@mol.f.u-tokyo.ac.jp,no comments,C Kaito 2005,2005,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4074,PHI:2965,UniProt,Q2FZ08,GenBank,BAF96735,,,,cvfA,,,,,,,1314,Streptococcus pyogenes,,SSI-9,infection,moths,7091,Bombyx mori (related: domestic silkworm),,,,,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,15853881,PubMed,10.1111/j.1365-2958.2005.04596.x,,kurokawa@mol.f.u-tokyo.ac.jp,no comments,C Kaito 2005,2005,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4075,PHI:2965,UniProt,Q2FZ08,GenBank,BAF96735,,,,cvfA,,,,,,,1314,Streptococcus pyogenes,,SSI-9,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,15853881,PubMed,10.1111/j.1365-2958.2005.04596.x,,kurokawa@mol.f.u-tokyo.ac.jp,no comments,C Kaito 2005,2005,,,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4076,PHI:2968,UniProt,J9VQA5,GenBank,AFR96662,,,H99,Hxs1,chromosome 8,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcal meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung,glucose uptake and transport,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation: characterised; gene complementation,,,RP,23691177,PubMed,10.1371/journal.pone.0064239,,xuech@umdnj.edu,Mutants sensitive to oxidative stress,T Liu 2013,2013,1 gene,Liu-2013-The glucose sensor-l,Batch030,2013-07-31,MC,,,,,,,,,,,,,
,,Record 4077,PHI:2969,UniProt,Q4WCZ1,GenBank,EAL85747,,,Af293,argEF,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,acetylglutamate kinase and acetylglutamyl-phosphate-reductase,,,,reduced virulence,,,,,,,,reduced,,no,eflornithine,eflornithine: CHEBI:41948,,,,,gene disruption; gene complementation,,,RP,2382566,PubMed,10.1371/journal.pone.0067426,,hubertus.haas@i-med.ac.at,Decreased resistance to the ornithine decarboxylase inhibitor eflornithine,N Beckmann 2013,2013,2 genes,Beckmann-2013-Characterization of,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4078,PHI:2970,UniProt,Q4WNW5,GenBank,EAL90069,,,Af293,argB,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,ornithine transcarbamoyl transferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,eflornithine,eflornithine: CHEBI:41948,,,,,gene disruption; gene complementation,,,RP,2382566,PubMed,10.1371/journal.pone.0067426,,hubertus.haas@i-med.ac.at,Unaffected resistance to the ornithine decarboxylase inhibitor eflornithine,N Beckmann 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4079,PHI:2971,UniProt,Q82ZX2,GenBank,AAO82613,,,V583,CspR,,,,,,,1351,Enterococcus faecalis,,EryS,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cold shock protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,23086208,PubMed,10.1128/JB.01673-12,,jean-christophe.giard@unicaen.fr,Mutant strain was more impaired in its growth than the parental strain under cold conditions and in its long-term survival under nutrient starvation,C Michaux 2012,2012,1 gene,"Michaux-2012-CspR, a cold shock R",Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4080,PHI:2971,UniProt,Q82ZX2,GenBank,AAO82613,,,V583,CspR,,,,,,,1351,Enterococcus faecalis,,EryS,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cold shock protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,23086208,PubMed,10.1128/JB.01673-12,,jean-christophe.giard@unicaen.fr,Mutant strain was more impaired in its growth than the parental strain under cold conditions and in its long-term survival under nutrient starvation,C Michaux 2012,2012,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4081,PHI:2972,UniProt,G1UB67,GenBank,EAL00435,,,SC5314,Efg1p,chromosome R,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract,"regulator of GI colonization, hyphal morphogenesis, and virulence",,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full,,,RP,23125349,PubMed,10.1128/EC.00236-12,,carol.kumamoto@tufts.edu,no comments,J V Pierce 2013,2013,1 gene,Pierce-2013-Normal adaptation of,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4082,PHI:2973,UniProt,Q3BTM6,GenBank,CAJ23833,,,85-10,XopJ,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23785289,PubMed,10.1371/journal.ppat.1003427,,fboernke@biologie.uni-erlangen.de,no comments,S Ustun 2013,2013,1 gene,Ustun-2013-The Xanthomonas camp,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4083,PHI:2974,UniProt,E2MMQ4,GenBank,EEB56752,,,T1,AvrRpt2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,15546361,PubMed,10.1111/j.1365-313X.2004.02251.x,,kunkel@biology.wustl.edu,no comments,M T S Lim 2004,2004,1 gene,Lim-2004-The Pseudomonas syri,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4084,PHI:2974,UniProt,E2MMQ4,GenBank,EEB56752,,,T1,AvrRpt2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Nossen-0,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,15546361,PubMed,10.1111/j.1365-313X.2004.02251.x,,kunkel@biology.wustl.edu,no comments,M T S Lim 2004,2004,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4085,PHI:2975,UniProt,Q9JP38,GenBank,AAF71498,,,DC3000,ipx10,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,11967070,PubMed,10.1046/j.1365-2958.2002.02877.x,,kunkel@biology.wustl.edu,no comments,J Boch 2002,2002,1 gene,Boch-2002-Identification of Ps,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4086,PHI:2975,UniProt,Q9JP38,GenBank,AAF71498,,,DC3000,ipx10,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Rio Grande 76S,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,11967070,PubMed,10.1046/j.1365-2958.2002.02877.x,,kunkel@biology.wustl.edu,no comments,J Boch 2002,2002,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4087,PHI:2976,UniProt,C6ZRH8,GenBank,FJ008981,,,,CgOPT1,,,,,,,474922,Colletotrichum gloeosporioides,29905,f. sp. aeschynomenes,anthracnose,eudicots,108276,Aeschynomene virginica (no common name found),,,,leaf,oligopeptide transporters of the OPT family,,,,reduced virulence,,,,,,reduced,,aberrant,,no,indole-3-acetic acid (IAA),indole-3-acetic acid (IAA): CHEBI:16411,,,,,altered gene expression / gene regulation: silencing,,,RP,19698103,PubMed,10.1186/1471-2180-9-173,,amirsh@ex.tau.ac.il,IAA enhanced spore formation and caused changes in colony morphology in the wild-type strain,V Chagué 2009,2009,1 gene,"Chague-2009-CgOpt1, a putative o",Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4088,PHI:2977,UniProt,F3REN8,GenBank,EGF37258,,,J1816,VirR,,,,,,,1639,Listeria monocytogenes,169963,EGD,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),BALB,,,spleen,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,16102006,PubMed,10.1111/j.1365-2958.2005.04776.x,,pcossart@pasteur.fr,no comments,P Mandin 2005,2005,1 gene,"Mandin-2005-VirR, a response reg",Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4089,PHI:2978,UniProt,G4N5V2,GenBank,EHA49727,,,70-15,MoCel12A,,,,,,,318829,Magnaporthe oryzae,,race 031 strain Ina72,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Shin 2,,,leaf,"endo-1,3-1,4-beta-glucanases in GH family 12",,,,unaffected pathogenicity,,,,,,increased,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,20680265,PubMed,10.1007/s00253-010-2781-2,,ttakeda@ibrc.or.jp,no comments,T Takeda 2010,2010,1 gene,Takeda-2010-Characterization of,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4090,PHI:2978,UniProt,G4N5V2,GenBank,EHA49727,,,70-15,MoCel12A,,,,,,,318829,Magnaporthe oryzae,,race 031 strain Ina72,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Shin 2,,,leaf,"endo-1,3-1,4-beta-glucanases in GH family 12",,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: partial,,,RP,20680265,PubMed,10.1007/s00253-010-2781-2,,ttakeda@ibrc.or.jp,no comments,T Takeda 2010,2010,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4091,PHI:2979,UniProt,Q5NHS6,GenBank,CAG45002,,,SCHU S4,DipA,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,,virulence factor,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,23840797,PubMed,10.1371/journal.pone.0067965,,chonga@niaid.nih.gov,no comments,A Chong 2013,2013,1 gene,Chong-2013-Structure-Function A,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4092,PHI:2980,UniProt,Q54151,GenBank,AAB58244,,,M4243A,pic,,,,,,,623,Shigella flexneri,198214,serotype 2a strain 301,shigellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,eye,auto-transporter protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23391153,PubMed,10.1186/1471-2180-13-31,,xjcheng@shmu.edu.cn,no comments,J Zhang 2013,2013,1 gene,Zhang-2013-Deletion of pic resu,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4093,PHI:2981,UniProt,A6N6J8,GenBank,ABR12478,,,,Ctf1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Vemar,,,root,transcriptional activator of cutinase and lipase genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,18705871,PubMed,10.1111/j.1364-3703.2007.00463.x,,ge1gorom@uco.es,no comments,A L M Rocha 2008,2008,1 gene,"Rocha-2008-Ctf1, a transcriptio",Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4094,PHI:2982,UniProt,B7HLG1,GenBank,ACJ80679,,,AH187,CodY,,,,,,,1396,Bacillus cereus,,F4810/72,gastrointestinal disease; localized infection; systemic infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,nutrient-responsive regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,22571587,PubMed,10.1111/j.1365-2958.2012.08090.x,,monika.ehling-schulz@vetmeduni.ac.at,no comments,E Frenzel 2012,2012,1 gene,Frenzel-2012-CodY orchestrates th,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4095,PHI:2983,UniProt,G4N8E3,GenBank,EHA50991,,,70-15,MGG_06279.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,Mutants sensitive to H2O2,S-Y Park 2013,2013,Multi genes,Park-2013-Global expression pr,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4096,PHI:2984,,no data found,,MGG_04951.6,,,70-15,MGG_04951.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,Mutants sensitive to H2O2,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4097,PHI:2985,UniProt,G4MSF2,GenBank,EHA53764,,,70-15,MGG_04521.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,Mutants sensitive to H2O2,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4098,PHI:2986,UniProt,G4N7A6,GenBank,EHA50816,,,70-15,MGG_06434.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,Mutants insensitive to H2O2,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4099,PHI:2987,UniProt,G4NID8,GenBank,EHA47998,,,70-15,MoAPS1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,no,,,,reduced,,,wild type,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,no comments,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4100,PHI:2988,UniProt,G4NA99,EMBL,EHA49649,,,70-15,MoAPS2,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,no,,,,reduced,,,wild type,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,no comments,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4101,PHI:2989,UniProt,G4N8I4,EMBL,EHA51032,,,70-15,MGG_06243.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,no,,,,reduced,,,,no,,,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,no comments,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4102,PHI:2990,UniProt,G4MRY7,EMBL,EHA56656,,,70-15,MGG_02474.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,no,,,,reduced,,,,no,,,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,no comments,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4103,PHI:2991,UniProt,Q52G60,EMBL,EHA54568,,,70-15,MGG_01426.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,no,,,,reduced,,,,no,,,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,no comments,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4104,PHI:2992,UniProt,Q01168,GenBank,AAB03415,,,70-15,MGG_02755.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,no,,,,reduced,,,,no,,,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,no comments,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4105,PHI:2993,,no data found,,ATMT0651A4,,,70-15,MoHOX2,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,no,,,,reduced,,,,no,,,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,no comments,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4106,PHI:2994,UniProt,G4N7V2,GenBank,EHA50906,,,70-15,MGG_06355.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,no,,,,aberrant,,,,no,,,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,no comments,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4107,PHI:2995,UniProt,G4MQ91,GenBank,EHA57284,,,70-15,MGG_09263.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,no,,,,aberrant,,,,no,,,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,no comments,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4108,PHI:2996,UniProt,G4N6W9,GenBank,EHA50733,,,70-15,MGG_06507.6,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,transcription factor,,,,reduced virulence,,no,,,,aberrant,,,,no,,,,,,,gene mutation,,,RP,23762023,PubMed,10.1371/journal.ppat.1003350,,yonglee@snu.ac.k,no comments,S-Y Park 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4109,PHI:2997,UniProt,Q82Z33,GenBank,AAO82913,,,V583,EF3245,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell-envelope associated acid phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23755154,PubMed,10.1371/journal.pone.0064875,,jose_lemos@urmc.rochester.edu,no comments,J Abranches 2013,2013,Multi genes,Abranches-2013-The Cell Wall-Target,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4110,PHI:2998,UniProt,Q834U9,GenBank,AAO81321,,,V583,EF1533,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23755154,PubMed,10.1371/journal.pone.0064875,,jose_lemos@urmc.rochester.edu,no comments,J Abranches 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4111,PHI:2999,UniProt,Q8KUC0,GenBank,AF454824_26,,,,EF0026,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23755154,PubMed,10.1371/journal.pone.0064875,,jose_lemos@urmc.rochester.edu,no comments,J Abranches 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4112,PHI:3000,UniProt,Q837N7,GenBank,AAO80611,,,V583,EF0797,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,conserved domain protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23755154,PubMed,10.1371/journal.pone.0064875,,jose_lemos@urmc.rochester.edu,no comments,J Abranches 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4113,PHI:3001,,no data found,GenBank,XM_001548468,,,B05.10,PMT1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,O-mannosyltransferases,,,,reduced virulence,,,yes,,,reduced,,reduced; aberrant,,no,calcofluor white (CW); Congo red (CR); sodium dodecyl sulphate,calcofluor white (CW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulphate: CHEBI:8984,,,,,gene deletion: full,,,RP,23762450,PubMed,10.1371/journal.pone.0065924,,cglez@ull.es,Growth rates wereimpapired for the mutants in the presence of cell wall perturbants,M Gonzalez 2013,2013,Multi genes,Gonzalez-2013-Botrytis cinerea Pro,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4114,PHI:3002,,no data found,GenBank,XM_001558267,,,B05.10,PMT2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,O-mannosyltransferases,,,,reduced virulence,,,yes,,,reduced,,reduced; aberrant,,no,calcofluor white (CW); Congo red (CR); sodium dodecyl sulphate,calcofluor white (CW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulphate: CHEBI:8984,,,,,gene deletion: full,,,RP,23762450,PubMed,10.1371/journal.pone.0065924,,cglez@ull.es,Growth rates wereimpapired for the mutants in the presence of cell wall perturbants,M Gonzalez 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4115,PHI:3003,,no data found,GenBank,XM_001558864,,,B05.10,PMT4,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,leaf,O-mannosyltransferases,,,,reduced virulence,,,yes,,,reduced,,reduced; aberrant,,no,calcofluor white (CW); Congo red (CR); sodium dodecyl sulphate,calcofluor white (CW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulphate: CHEBI:8984,,,,,gene deletion: full,,,RP,23762450,PubMed,10.1371/journal.pone.0065924,,cglez@ull.es,Growth rates wereimpapired for the mutants in the presence of cell wall perturbants,M Gonzalez 2013,2013,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4116,PHI:3004,UniProt,A6QHK8,EMBL,BAF67840,,,Newman,ClpX,,,,,,,1280,Staphylococcus aureus,93061,NCTC 8325-4,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,part of proteolytic complex,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,12791139,PubMed,10.1046/j.1365-2958.2003.03524.x,,ingmer@biobase.dk,ClpX and clpP mutant cells are sensitive to hydrogen peroxide,D Frees 2003,2003,2 genes,Frees-2003-Alternative roles of,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4117,PHI:3005,UniProt,P63786,GenBank,BAB94595,,,MW2,ClpP,,,,,,,1280,Staphylococcus aureus,93061,NCTC 8325-4,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,part of proteolytic complex,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,12791139,PubMed,10.1046/j.1365-2958.2003.03524.x,,ingmer@biobase.dk,ClpX and clpP mutant cells are sensitive to hydrogen peroxide,D Frees 2003,2003,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4118,PHI:3006,UniProt,A7KT66,GenBank,ABS82113,,,6A_NorthCarolina_23,rrgA,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,ancillary pilus subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,12207705,PubMed,10.1046/j.1365-2958.2002.03106.x,,andrew.camilli@tufts.edu,no comments,D L Hava 2002,2002,Multi genes,Hava-2002-Large-scale identifi,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4119,PHI:3007,UniProt,A7KT36,GenBank,ABS82083,,,19F_Portugal_21,srtD,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,sortase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12207705,PubMed,10.1046/j.1365-2958.2002.03106.x,,andrew.camilli@tufts.edu,no comments,D L Hava 2002,2002,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4120,PHI:3008,UniProt,Q9S1J0,GenBank,AF221126_1,,,,zmpR,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,putative response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12207705,PubMed,10.1046/j.1365-2958.2002.03106.x,,andrew.camilli@tufts.edu,no comments,D L Hava 2002,2002,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4121,PHI:3009,UniProt,Q9S1K2,GenBank,CAB54566,,,,rr01,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12207705,PubMed,10.1046/j.1365-2958.2002.03106.x,,andrew.camilli@tufts.edu,no comments,D L Hava 2002,2002,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4122,PHI:3010,UniProt,Q97NM0,GenBank,AAK76069,,,TIGR4,STM237,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12207705,PubMed,10.1046/j.1365-2958.2002.03106.x,,andrew.camilli@tufts.edu,no comments,D L Hava 2002,2002,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4123,PHI:3011,UniProt,P58662,GenBank,AAL21172,,,LT2,rcsC11,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sensor protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,15469511,PubMed,10.1111/j.1365-2958.2004.04293.x,,groisman@borcim.wustl.edu,no comments,C Mouslim 2004,2004,Multi genes,Mouslim-2004-Activation of the Rc,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4124,PHI:3012,UniProt,C4PCU2,GenBank,ACQ91082,,,SL1344,rcsB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,RcsA and RcsB form a complex to promote transcription of the genes for capsule synthesis.,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,15469511,PubMed,10.1111/j.1365-2958.2004.04293.x,,groisman@borcim.wustl.edu,no comments,C Mouslim 2004,2004,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4125,PHI:3013,UniProt,P54698,GenBank,AAL20894,,,LT2,rcsA,,,,,,PHI:3011,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,positive regulator of capsular polysaccharide synthesis. RcsA and RcsB form a complex to promote transcription of the genes for capsule synthesis.,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,15469511,PubMed,10.1111/j.1365-2958.2004.04293.x,,groisman@borcim.wustl.edu,no comments,C Mouslim 2004,2004,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4126,PHI:3011,UniProt,P58662,GenBank,AAL21172,,,LT2,rcsC11,,,,,,PHI:3012,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sensor protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,15469511,PubMed,10.1111/j.1365-2958.2004.04293.x,,groisman@borcim.wustl.edu,no comments,C Mouslim 2004,2004,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4127,PHI:3012,UniProt,C4PCU2,GenBank,ACQ91082,,,SL1344,rcsB,,,,,,PHI:3011,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,RcsA and RcsB form a complex to promote transcription of the genes for capsule synthesis.,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,15469511,PubMed,10.1111/j.1365-2958.2004.04293.x,,groisman@borcim.wustl.edu,no comments,C Mouslim 2004,2004,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4128,PHI:3011,UniProt,P58662,GenBank,AAL21172,,,LT2,rcsC11,,,,,,PHI:3013,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sensor protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,15469511,PubMed,10.1111/j.1365-2958.2004.04293.x,,groisman@borcim.wustl.edu,no comments,C Mouslim 2004,2004,,,Batch030,2013-08-01,MC,,,,,,,,,,,,,
,,Record 4129,PHI:3531,UniProt,G7RUY1,GenBank,AET17086,,,U-0608239,pld1,,,,,,,573,Klebsiella pneumoniae,,Kp52.145,urinary tract infection; nosocomial pneumonia; abdominal infection,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,lung,lipid metabolism,,,,loss of pathogenicity,,,,,,,reduced,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24885329,PubMed,10.1186/1741-7007-12-41,,llery@biof.ufrj.b r,,L M S Lery 2014,2014,1 gene,Lery-2014-Comparative analysis of Klebsiella p,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4130,PHI:3530,UniProt,G4YTW4,GenBank,EGZ25435,,,P6497,PsMPK7,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Hefeng 47,,,leaf,stress-associated mitogen-activated protein kinase,,,MAPK pathway,reduced virulence,,no,no,,,,,wild type,reduced,no,H2O2; sorbitol; NaCl; CaCl2,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; CaCl2: CHEBI:3312,,,,,altered gene expression / gene regulation: silencing,,,RP,24889742,PubMed,10.1111/mpp.12163,,wangyc@njau.edu.cn,"PsMPK7 gene encodes a stress-associated MAPK in P. sojae that is important not only for responses to various stresses, but also for ROS detoxification",J GAO 2014,2014,1 gene,"Gao-2014-PsMPK7, a stress-associated MAPK in P",Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4131,PHI:3014,UniProt,G5EHD3,GenBank,EAQ71329,,,70-15,MoAND1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,cell cortex proteins involved in nuclear migration and positioning.,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,24875422,PubMed,10.1016/j.fgb.2014.05.002,,yonglee@snu.ac.kr,,J Jeon 2014,2014,1 gene,Jeon-2014-Role of MoAND1-mediated nuclear posi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4132,PHI:3015,UniProt,Q3K359,GenBank,ABA45697,,,A909,LiaR,,,,,,,1311,Streptococcus agalactiae,205921,A909,streptococcal pharyngitis; necrotizing fasciitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung; spleen,response regulator,,,,reduced virulence,,,,,,,,,,no,vancomycin; bacitracin; colistin; nisin; ampicillin; cefotaxime; polymixin B; LL-37,vancomycin: CHEBI:28001; bacitracin: CHEBI:28669; colistin: CHEBI:37943; nisin: CHEBI:71629; ampicillin: CHEBI:28971; cefotaxime: CHEBI:204928; polymixin B: CHEBI:8309,,,,,gene disruption; gene complementation,,,RP,23704792,PubMed,10.1099/mic.0.064444-0,,kpuopolo@partners.org,,D C Klinzing 2013,2013,1 gene,Klinzing-2013-The two-component response regul,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4133,PHI:3015,UniProt,Q3K359,GenBank,ABA45697,,,A909,LiaR,,,,,,,1311,Streptococcus agalactiae,205921,A909,streptococcal pharyngitis; necrotizing fasciitis,rodents,10090,Mus musculus (related: house mouse),FVB/N,,,lung; spleen,response regulator,,,,reduced virulence,,,,,,,,,,no,vancomycin; bacitracin; colistin; nisin; ampicillin; cefotaxime; polymixin B; LL-37,vancomycin: CHEBI:28001; bacitracin: CHEBI:28669; colistin: CHEBI:37943; nisin: CHEBI:71629; ampicillin: CHEBI:28971; cefotaxime: CHEBI:204928; polymixin B: CHEBI:8309,,,,,gene disruption; gene complementation,,,RP,23704792,PubMed,10.1099/mic.0.064444-0,,kpuopolo@partners.org,,D C Klinzing 2013,2013,1 gene,Klinzing-2013-The two-component response regul,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4134,PHI:3016,,no data found,GenBank,KJ402294,,,,MaCnA,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,larva,"growth, conidiation, stress response, and pathogenicity",,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,caspofungin; CFW,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,RP,24931310,PubMed,10.1007/s00253-014-5876-3,,yueqingcao@cqu.edu.cn,"MaCnA mutant was more tolerant to cell wall-perturbing agents and elevated or decreased exogenous calcium but less tolerant to heat, ultraviolet irradiation, and caspofungin than the wild type.",Y Cao 2014,2014,1 gene,"Cao-2014-Calcineurin modulates growth, stress",Batch039,2014-07-01,MC,"KJ402294= mentioned by the author as the nucleotide ID, but could not find it anywhere, so taken as is",,,,,,,,,,,,
,,Record 4135,PHI:3017,UniProt,J9VXZ9,GenBank,AFR97484,,,H99,Mpr1,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung; brain,secreted metalloprotease; fungalysins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24895304,PubMed,10.1128/mBio.01101-14,,acgelli@ucdavis.edu,,K Vu 2014,2014,1 gene,Vu-2014-Invasion of the central nervous system,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4136,PHI:3018,UniProt,B7VSJ8,GenBank,CAV26579,,,LGP32,Vsp,,,,,,,212663,Vibrio tasmaniensis,575788,LGP32,,bivalves,29159,Crassostrea gigas (related: pacific oyster),,,,,gelatinase/caseinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,24919412,PubMed,10.1111/1462-2920.12535,,ddestoum@univ-montp2.fr,,A S Vanhove 2014,2014,1 gene,Vanhove-2014-Outer membrane vesicles are vehic,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4137,PHI:3019,UniProt,G5EI34,GenBank,EAQ70925,,,70-15,MoLys2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,AA reductase,,,lysine synthetic pathway,reduced virulence,,no,,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731804,PubMed,10.1016/j.fgb.2014.04.001,,zhgzhang@njau.edu.cn,,Y Chen 2014,2014,1 gene,"Chen-2014-MoLys2 is necessary for growth, coni",Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4138,PHI:3020,UniProt,Q5AKU6,GenBank,AF084608_1,,,SC5314,ssk1,,,,,,PHI:3021; PHI:3022; PHI:3023,5476,Candida albicans,,CAF2-1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney; liver; spleen,MAP kinases,,,Cek1 and Hog1 pathways,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene mutation,,,RP,24905535,PubMed,10.1016/j.fgb.2014.05.010,,realonso@ucm.es,,C Herrero-de-Dios 2014,2014,4 genes,Herrero-de-Dios-2014-The lack of upstream elem,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4139,PHI:3021,UniProt,Q5ALT5,GenBank,EAL03648,,,SC5314,msb2,,,,,,PHI:3020; PHI:3022; PHI:3023,5476,Candida albicans,,CAF2-1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney; liver; spleen,MAP kinases,,,Cek1 and Hog1 pathways,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26711,,,,,gene mutation,,,RP,24905535,PubMed,10.1016/j.fgb.2014.05.010,,realonso@ucm.es,,C Herrero-de-Dios 2014,2014,4 genes,Herrero-de-Dios-2014-The lack of upstream elem,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4140,PHI:3022,UniProt,Q5AQ36,GenBank,CAC81238,,,1001,sho1,,,,,,PHI:3020; PHI:3021; PHI:3023,5476,Candida albicans,,CAF2-1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney; liver; spleen,MAP kinases,,,Cek1 and Hog1 pathways,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26712,,,,,gene mutation,,,RP,24905535,PubMed,10.1016/j.fgb.2014.05.010,,realonso@ucm.es,,C Herrero-de-Dios 2014,2014,4 genes,Herrero-de-Dios-2014-The lack of upstream elem,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4141,PHI:3023,UniProt,Q5A753,GenBank,EAK98608,,,SC5314,opy2,,,,,,PHI:3020; PHI:3021; PHI:3022,5476,Candida albicans,,CAF2-1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney; liver; spleen,MAP kinases,,,Cek1 and Hog1 pathways,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26713,,,,,gene mutation,,,RP,24905535,PubMed,10.1016/j.fgb.2014.05.010,,realonso@ucm.es,,C Herrero-de-Dios 2014,2014,4 genes,Herrero-de-Dios-2014-The lack of upstream elem,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4142,PHI:3024,UniProt,J9VV14,GenBank,AFR98317,,,H99,Cln1,,,,,,,5207,Cryptococcus neoformans,235443,H99,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,G 1 /S cyclin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24939886,PubMed,10.1128/mBio.00945-14,,ozaragoza@isciii.es,"This cyclin mutant is avirulent at 37°C, but as virulent as the wild type at lower temperatures.",R García-Rodas 2014,2014,1 gene,Garcia-Rodas-2014-Capsule Growth in Cryptococc,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4143,PHI:3025,UniProt,X5IFG8,GenBank,BAO58974,,,,RnPKS1,,,,,,,77044,Rosellinia necatrix,,W97,white root rot,eudicots,106564,Malus prunifolia (no common name found),cv. Ringo,,,root,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24742836,PubMed,10.1016/j.funbio.2014.02.006,,satokok@affrc.go.jp,,T SHIMIZU 2014,2014,1 gene,Shimizu-2014-Functional analysis of a melanin,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4144,PHI:3026,UniProt,O34208,GenBank,AAC16023,,,PA103,ExoU,,,,,,,287,Pseudomonas aeruginosa,1081927,PA103,septicemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,phospholipase A2 effector exotoxin,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,functional test in host: transient expression,,,RP,24821799,PubMed,10.1073/pnas.1400782111,,barbara.kazmierczak@yale.edu,Mice infected withdeltaexsA:WT had a greater bacterial burden than other groups at 12 hpi,K Czechowska 2013,2014,1 gene,Czechowska-2014-Cheating by type 3 secretion s,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4145,PHI:3027,UniProt,A5CUE1,GenBank,CAN02728,,,NCPPB 382,Vatr1,,,,,,,28447,Clavibacter michiganensis,443906,subsp. michiganensis strain NCPPB382,wilt (tomato); canker (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Rio Grande,,,leaf,TetR family of transcriptional regulators,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,24940988,PubMed,10.1094/MPMI-02-14-0061-R,,guidos@post.tau.ac.il,,A Savidor 2014,2014,2 genes,Savidor-2014-Clavibacter michiganensis subsp.,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4146,PHI:3028,UniProt,A5CVB7,GenBank,CAN03056,,,NCPPB 382,Vatr2,,,,,,,28447,Clavibacter michiganensis,443906,subsp. michiganensis strain NCPPB382,wilt (tomato); canker (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Rio Grande,,,leaf,MocR family of transcriptional regulators,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,24940988,PubMed,10.1094/MPMI-02-14-0061-R,,guidos@post.tau.ac.il,,A Savidor 2014,2014,2 genes,Savidor-2014-Clavibacter michiganensis subsp.,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4147,PHI:3029,UniProt,Q5KAF1,GenBank,AAW45848,,,JEC21,PMT2,,,,,,,5207,Cryptococcus neoformans,214684,JEC21,,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,protein-O-mannosyltransferase,,,,increased virulence (hypervirulence),yes,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24892554,PubMed,10.1016/j.fgb.2014.05.007,,shimizuy@kanto-gakuin.ac.jp,,K Shimizu 2014,2014,3 genes,Shimizu-2014-Functional characterization of PM,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4148,PHI:3029,UniProt,Q5KAF1,GenBank,AAW45848,,,JEC21,PMT2,,,,,,PHI:3030,5207,Cryptococcus neoformans,214684,JEC21,,,,,Lethal pathogen phenotype,,,,protein-O-mannosyltransferase,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full; gene complementation,,,RP,24892554,PubMed,10.1016/j.fgb.2014.05.007,,shimizuy@kanto-gakuin.ac.jp,,K Shimizu 2014,2014,3 genes,Shimizu-2014-Functional characterization of PM,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4149,PHI:3030,UniProt,F5HFL6,GenBank,EAL21558,,,B-3501A,PMT1,chromosome 4,,,,,PHI:3029,5207,Cryptococcus neoformans,214684,JEC21,,,,,Lethal pathogen phenotype,,,,protein-O-mannosyltransferase,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full; gene complementation,,,RP,24892554,PubMed,10.1016/j.fgb.2014.05.007,,shimizuy@kanto-gakuin.ac.jp,,K Shimizu 2014,2014,3 genes,Shimizu-2014-Functional characterization of PM,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4150,PHI:3029,UniProt,Q5KAF1,GenBank,AAW45848,,,JEC21,PMT2,,,,,,PHI:3031,5207,Cryptococcus neoformans,214684,JEC21,,,,,Lethal pathogen phenotype,,,,protein-O-mannosyltransferase,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full; gene complementation,,,RP,24892554,PubMed,10.1016/j.fgb.2014.05.007,,shimizuy@kanto-gakuin.ac.jp,,K Shimizu 2014,2014,3 genes,Shimizu-2014-Functional characterization of PM,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4151,PHI:3031,UniProt,A3E242,GenBank,ABG57096,,,,PMT4,chromosome 5,,,,,PHI:3029,5207,Cryptococcus neoformans,214684,JEC21,,,,,Lethal pathogen phenotype,,,,protein-O-mannosyltransferase,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full; gene complementation,,,RP,24892554,PubMed,10.1016/j.fgb.2014.05.007,,shimizuy@kanto-gakuin.ac.jp,,K Shimizu 2014,2014,3 genes,Shimizu-2014-Functional characterization of PM,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4152,PHI:3032,UniProt,Q595M4,GenBank,AAS65538,,,R,GapA,,,,,,,2096,Mycoplasmoides gallisepticum,,Ap3AS,sinusitis (turkey); airsacculitis (chicken); tracheitis (chicken),birds,9031,Gallus gallus (related: chicken),,,,alveolus,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23657682,PubMed,10.1099/mic.0.067553-0,,glenfb@unimelb.edu.au,,C Tseng 2013,2013,3 genes,Tseng-2013-MalF is essential for persistence o,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4153,PHI:3033,UniProt,D3FJS3,GenBank,ADC31130,,,F,CrmA,,,,,,,2096,Mycoplasmoides gallisepticum,,Ap3AS,sinusitis (turkey); airsacculitis (chicken); tracheitis (chicken),birds,9031,Gallus gallus (related: chicken),,,,alveolus,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23657682,PubMed,10.1099/mic.0.067553-0,,glenfb@unimelb.edu.au,,C Tseng 2013,2013,3 genes,Tseng-2013-MalF is essential for persistence o,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4154,PHI:3034,UniProt,V5W1E0,GenBank,AHB99551,,,S6,malF,,,,,,,2096,Mycoplasmoides gallisepticum,,Ap3AS,sinusitis (turkey); airsacculitis (chicken); tracheitis (chicken),birds,9031,Gallus gallus (related: chicken),,,,alveolus,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23657682,PubMed,10.1099/mic.0.067553-0,,glenfb@unimelb.edu.au,,C Tseng 2013,2013,3 genes,Tseng-2013-MalF is essential for persistence o,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4155,PHI:3035,UniProt,I1RFM2,GenBank,ESU07949,,,PH-1,FgERG3A,,,,,,PHI:3036,5518,Fusarium graminearum,,HN9-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,C-5 sterol desaturase,,,ergosterol biosynthesis pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,24785759,PubMed,10.1016/j.fgb.2014.04.010,,chenyun0927@zju.edu.cn,,Y Yun 2014,2014,4 genes,Yun-2014-Functional characterization of FgERG3,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4156,PHI:3036,UniProt,A0A0E0SNE8,EMBL,FGRAMPH1_01T16829,,,PH-1,FgERG3B,,,,,,PHI:3035,5518,Fusarium graminearum,,HN9-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,C-5 sterol desaturase,,,ergosterol biosynthesis pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,24785759,PubMed,10.1016/j.fgb.2014.04.010,,chenyun0927@zju.edu.cn,,Y Yun 2014,2014,4 genes,Yun-2014-Functional characterization of FgERG3,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4157,PHI:3037,UniProt,I1RE80,GenBank,ESU07330,,,PH-1,FgERG5A,,,,,,PHI:3038,5518,Fusarium graminearum,,HN9-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,cytochrome P450 61,,,ergosterol biosynthesis pathway,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,24785759,PubMed,10.1016/j.fgb.2014.04.010,,chenyun0927@zju.edu.cn,,Y Yun 2014,2014,4 genes,Yun-2014-Functional characterization of FgERG3,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4158,PHI:3038,UniProt,A0A098DJ84,EMBL,FGRAMPH1_01T13463,,,PH-1,FgERG5B,,,,,,PHI:3037,5518,Fusarium graminearum,,HN9-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,cytochrome P450 61,,,ergosterol biosynthesis pathway,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,24785759,PubMed,10.1016/j.fgb.2014.04.010,,chenyun0927@zju.edu.cn,,Y Yun 2014,2014,4 genes,Yun-2014-Functional characterization of FgERG3,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4159,PHI:3039,UniProt,U3MXJ8,GenBank,AGW22216,,,,MoSPA2,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,"involved in the establishment, maintenance, termination of polarized cell growth and is important for defining tip growth of filamentous fungi.",,,,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24859315,PubMed,10.1007/s00294-014-0431-4,,yangj@cau.edu.cn,,C Li 2014,2014,1 gene,Li-2014-A spindle pole antigen gene MoSPA2 is,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4160,PHI:3039,UniProt,U3MXJ8,GenBank,AGW22216,,,,MoSPA2,,,,,,,318829,Magnaporthe oryzae,,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,"involved in the establishment, maintenance, termination of polarized cell growth and is important for defining tip growth of filamentous fungi.",,,,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24859315,PubMed,10.1007/s00294-014-0431-4,,yangj@cau.edu.cn,,C Li 2014,2014,1 gene,Li-2014-A spindle pole antigen gene MoSPA2 is,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4161,PHI:3040,UniProt,P0A1D7,GenBank,BAA94668,,,x3306,ClpP,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain C5,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,proteolytic component,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23676436,PubMed,10.1099/mic.0.065797-0,,gmkn@bio.dtu.dk,,G M Knudsen 2013,2013,1 gene,Knudsen-2013-ClpP deletion causes attenuation,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4162,PHI:3041,UniProt,Q9I3S1,GenBank,AE004571_11,,,PAO1,BdlA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,septicemia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,chemotaxis transducer protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24901523,PubMed,10.1371/journal.ppat.1004168,,ksauer@binghamton.edu,,Y Li 2014,2014,2 genes,"Li-2014-BdlA, DipA and Induced Dispersion Cont",Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4163,PHI:3042,UniProt,Q9HUF2,GenBank,AE004914_3,,,PAO1,DipA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,septicemia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,phosphodiesterases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24901523,PubMed,10.1371/journal.ppat.1004168,,ksauer@binghamton.edu,,Y Li 2014,2014,2 genes,"Li-2014-BdlA, DipA and Induced Dispersion Cont",Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4164,PHI:3041,UniProt,Q9I3S1,GenBank,AE004571_11,,,PAO1,BdlA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,septicemia,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,chemotaxis transducer protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24901523,PubMed,10.1371/journal.ppat.1004168,,ksauer@binghamton.edu,,Y Li 2014,2014,2 genes,"Li-2014-BdlA, DipA and Induced Dispersion Cont",Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4165,PHI:3043,UniProt,Q667Y0,GenBank,CAH22098,,,IP 32953,IscR,,,,,,,633,Yersinia pseudotuberculosis,,IP2666,gastrointestinal disease; yersiniosis,rodents,10090,Mus musculus (related: house mouse),129S6/SvEvTac,,,Peyer's gland; mesenteric lymph node; spleen; liver,type III secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24945271,PubMed,10.1371/journal.ppat.1004194,,vastone@ucsc.edu,,H K Miller 2014,2014,1 gene,Miller-2014-IscR Is Essential for Yersinia pse,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4166,PHI:3044,UniProt,P54267,GenBank,CAA63928,,,H237,CHSG,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,chitin synthesase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4167,PHI:3044,UniProt,P54267,GenBank,CAA63928,,,H237,CHSG,,,,,,PHI:3045; PHI:3046; PHI:3047,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,chitin synthesase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4168,PHI:3045,UniProt,Q4WIH1,GenBank,EAL87284,,,Af293,CHSA,,,,,,PHI:3044; PHI:3046; PHI:3047,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,chitin synthesase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4169,PHI:3046,UniProt,Q4W9P7,GenBank,EAL84566,,,Af293,CHSB,,,,,,PHI:3044; PHI:3045; PHI:3047,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,chitin synthesase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4170,PHI:3047,UniProt,Q92197,GenBank,CAA63929,,,H237,CHSC,,,,,,PHI:3044; PHI:3045; PHI:3046,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,chitin synthesase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4171,PHI:3044,UniProt,P54267,GenBank,CAA63928,,,H237,CHSG,,,,,,PHI:3048; PHI:3049; PHI:3050,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,chitin synthesase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4172,PHI:3048,UniProt,Q4X0H6,GenBank,EAL93639,,,Af293,CSMA,,,,,,PHI:3044; PHI:3049; PHI:3050,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,chitin synthesase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4173,PHI:3049,UniProt,Q4X0H7,GenBank,EAL93638,,,Af293,CSMB,,,,,,PHI:3048; PHI:3049; PHI:3050,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,chitin synthesase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4174,PHI:3050,UniProt,Q4WC58,GenBank,EAL85326,,,Af293,CHSF,,,,,,PHI:3044; PHI:3048; PHI:3049,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,chitin synthesase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4175,PHI:3044,UniProt,P54267,GenBank,CAA63928,,,H237,CHSG,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,chitin synthesase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4176,PHI:3044,UniProt,P54267,GenBank,CAA63928,,,H237,CHSG,,,,,,PHI:3045; PHI:3046; PHI:3047,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,chitin synthesase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4177,PHI:3045,UniProt,Q4WIH1,GenBank,EAL87284,,,Af293,CHSA,,,,,,PHI:3044; PHI:3046; PHI:3047,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,chitin synthesase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4178,PHI:3046,UniProt,Q4W9P7,GenBank,EAL84566,,,Af293,CHSB,,,,,,PHI:3044; PHI:3045; PHI:3047,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,chitin synthesase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4179,PHI:3047,UniProt,Q92197,GenBank,CAA63929,,,H237,CHSC,,,,,,PHI:3044; PHI:3045; PHI:3046,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,chitin synthesase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4180,PHI:3044,UniProt,P54267,GenBank,CAA63928,,,H237,CHSG,,,,,,PHI:3048; PHI:3049; PHI:3050,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,chitin synthesase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4181,PHI:3048,UniProt,Q4X0H6,GenBank,EAL93639,,,Af293,CSMA,,,,,,PHI:3044; PHI:3049; PHI:3050,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,chitin synthesase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4182,PHI:3049,UniProt,Q4X0H7,GenBank,EAL93638,,,Af293,CSMB,,,,,,PHI:3048; PHI:3049; PHI:3050,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,chitin synthesase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4183,PHI:3050,UniProt,Q4WC58,GenBank,EAL85326,,,Af293,CHSF,,,,,,PHI:3044; PHI:3048; PHI:3049,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,chitin synthesase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole; amphotericin B; nikkomycin Z,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; nikkomycinZ: CHEBI:623918,,,,,gene deletion: full,,,RP,24946720,PubMed,10.1111/cmi.12326,,jplatge@pasteur.fr,,L Muszkieta 2014,2014,7 genes,Muszkieta-2014-Deciphering the role of the chi,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4184,PHI:3051,UniProt,Q9S108,GenBank,BAA84895,,,B171,Aar,,,,,,,562,Escherichia coli,216592,042,Traveler's diarrhea,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon,regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24875828,PubMed,10.1371/journal.ppat.1004153,,aes8j@virginia.edu,,A E Santiago 2014,2014,1 gene,Santiago-2014-A Large Family of Antivirulence,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4185,PHI:3052,UniProt,W7LWT0,GenBank,EWG36987,,,7600,FvHAP2,,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays,,,stem,primary and secondary metabolism,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,24875423,PubMed,10.1016/j.fgb.2014.05.003,,bbluhm@uark.edu,,J B Ridenour 2014,2014,3 genes,Ridenour-2014-The HAP complex in Fusarium vert,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4186,PHI:3053,UniProt,W7MB59,GenBank,EWG48238,,,7600,FvHAP3,,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays,,,stem,primary and secondary metabolism,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,24875423,PubMed,10.1016/j.fgb.2014.05.003,,bbluhm@uark.edu,,J B Ridenour 2014,2014,3 genes,Ridenour-2014-The HAP complex in Fusarium vert,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4187,PHI:3054,UniProt,W7MQF2,GenBank,EWG49850,,,7600,FvHAP5,,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays,,,stem,primary and secondary metabolism,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,24875423,PubMed,10.1016/j.fgb.2014.05.003,,bbluhm@uark.edu,,J B Ridenour 2014,2014,3 genes,Ridenour-2014-The HAP complex in Fusarium vert,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4188,PHI:3055,UniProt,Q9L8G8,GenBank,AF204737_1,,,C7184O,smcR,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,septicemia,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,major QS regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24769338,PubMed,10.1016/j.micpath.2014.04.001,,joonhee@pusan.ac.kr,,C Ha 2014,2014,3 genes,Ha-2014-Quorum sensing-dependent metalloprotea,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4189,PHI:3056,UniProt,Q0PRN7,GenBank,ABG81424,,,ATCC 29307,luxO,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,septicemia,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,upstream negative regulator of smcR,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24769338,PubMed,10.1016/j.micpath.2014.04.001,,joonhee@pusan.ac.kr,,C Ha 2014,2014,3 genes,Ha-2014-Quorum sensing-dependent metalloprotea,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4190,PHI:3057,UniProt,C3VHN8,GenBank,ACP30470,,,CKUH,VvpE,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,septicemia,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,QS-dependent exoprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24769338,PubMed,10.1016/j.micpath.2014.04.001,,joonhee@pusan.ac.kr,,C Ha 2014,2014,3 genes,Ha-2014-Quorum sensing-dependent metalloprotea,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4191,PHI:3057,UniProt,C3VHN8,GenBank,ACP30470,,,CKUH,VvpE,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,septicemia,crustaceans,85549,Artemia salina (no common name found),,,,larva,QS-dependent exoprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24769338,PubMed,10.1016/j.micpath.2014.04.001,,joonhee@pusan.ac.kr,,C Ha 2014,2014,3 genes,Ha-2014-Quorum sensing-dependent metalloprotea,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4192,PHI:3058,UniProt,P0C1S0,GenBank,AAP48794,,,Becker,MgrA,,,,,,,1280,Staphylococcus aureus,,Newman D2C,pneumonia; toxic shock syndrome; bacteremia; endocarditis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; spleen; liver; kidney,global regulator; member of the MarR (multiple antibiotic resistance regulator)/SarA (staphylococcal accessory regulator A) family proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24746531,PubMed,10.1016/j.micpath.2014.03.012,,tjszyong@163.com,,C Liu 2014,2014,1 gene,Liu-2014-The impact of mgrA on progression of,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4193,PHI:3059,UniProt,Q9KTE2,GenBank,AAF94122,,,N16961,YbeY,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,essential endoribonuclease,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24901994,PubMed,10.1371/journal.ppat.1004175,,gwalker@mit.edu,,M Vercruysse 2014,2014,1 gene,Vercruysse-2014-The Highly Conserved Bacterial,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4194,PHI:3060,UniProt,G4MZD0,GenBank,EHA53685,,,70-15,Molrg1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,Rho GTPase activating proteins,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4195,PHI:3061,UniProt,G4NF65,GenBank,EHA47270,,,70-15,MoRga1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,yes,,,,reduced; aberrant,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4196,PHI:3062,UniProt,G4N7K5,GenBank,EHA50862,,,70-15,MoRga2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4197,PHI:3063,UniProt,G4NKL4,GenBank,EHA45889,,,70-15,MoRga3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4198,PHI:3064,UniProt,G4N1D0,GenBank,EHA52401,,,70-15,MoRga4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4199,PHI:3065,UniProt,G4MQQ3,GenBank,EHA57340,,,70-15,MoRga5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4200,PHI:3066,UniProt,G4MQB0,GenBank,EHA57304,,,70-15,MoRga6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4201,PHI:3067,UniProt,G4NGW7,GenBank,EHA47477,,,70-15,MoRga7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4202,PHI:3060,UniProt,G4MZD0,GenBank,EHA53685,,,70-15,Molrg1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Jinchang 1316,,,leaf,Rho GTPase activating proteins,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4203,PHI:3061,UniProt,G4NF65,GenBank,EHA47270,,,70-15,MoRga1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Jinchang 1316,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,yes,,,,reduced; aberrant,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4204,PHI:3062,UniProt,G4N7K5,GenBank,EHA50862,,,70-15,MoRga2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Jinchang 1316,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4205,PHI:3063,UniProt,G4NKL4,GenBank,EHA45889,,,70-15,MoRga3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Jinchang 1316,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4206,PHI:3064,UniProt,G4N1D0,GenBank,EHA52401,,,70-15,MoRga4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Jinchang 1316,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4207,PHI:3065,UniProt,G4MQQ3,GenBank,EHA57340,,,70-15,MoRga5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Jinchang 1316,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4208,PHI:3066,UniProt,G4MQB0,GenBank,EHA57304,,,70-15,MoRga6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Jinchang 1316,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4209,PHI:3067,UniProt,G4NGW7,GenBank,EHA47477,,,70-15,MoRga7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Jinchang 1316,,,leaf,Rho GTPase activating proteins,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24731806,PubMed,10.1016/j.fgb.2014.03.008,,wangzh@fjau.edu.cn,,W Ye 2014,2014,8 genes,Ye-2014-Putative RhoGAP proteins orchestrate v,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4210,PHI:3523,UniProt,B0LFQ7,GenBank,ABW81468,,,,Bx-Prx,,,,,,,6326,Bursaphelenchus xylophilus,,,pine wilt,seed plants,3350,Pinus thunbergii (related: japanese black pine),,,,leaf; cone,reproduction and pathogenicity,,,,loss of pathogenicity,yes,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24918285,PubMed,10.3390/ijms150610215,,jryenjfu2014@gmail.com,,H Fu 2014,2014,1 gene,Fu-2014-Screening and Functional Analysis of t,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4211,PHI:3519,UniProt,Q0P928,GenBank,CAL35343,,,NCTC 11168,HtrA,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon; liver; kidney; lung,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24883112,PubMed,10.1186/1757-4749-6-16,,markus.heimesaat@charite.de,"UponC. jejunideltahtrAstrain infection of infant mice, intestinal and extra-intestinal pro-inflammatory immune responses were ameliorated in the infant mouse model system.",M M Heimesaat 2014,2014,1 gene,Heimesaat-2014-The impact of serine protease H,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4212,PHI:3068,UniProt,J4UTE1,GenBank,EJP69082,,,ARSEF 2860,BbAC,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,adenylate cyclase,,,cAMP signalling network,reduced virulence,,,,,median lethal time (LT50)estimates ofDBbACandDMrACagainst susceptible insects were 10.9 and 1.4 d longer than those from wild-type strains respectively,increased,,reduced,reduced,no,H2O2; menadione; Congo red; carbendazim; NaCl; EDTA; cu2+; mn2+; zn2+; fe3+,"H2O2: CAS:7722-84-1; menadione: CHEBI:28869; Congo red: CHEBI:34653; carbendazim: CHEBI:3392, CAS:10605-21-7; NaCl: CHEBI:26710; EDTA: CHEBI:64758; cu2+: CHEBI:29036; mn2+: CHEBI:29035; zn2+: CHEBI:29105; fe3+: CHEBI:29034",,,,,gene deletion: full; gene complementation,,,RP,24742837,PubMed,10.1016/j.funbio.2014.03.001,,mgfeng@zju.edu.cn,"DBbAC was highly sensitive to oxidation, high osmolarity, cell wall perturbation, carbendazim fungicide, Mn, Zn,Fe, and EDTA but more tolerant to Cu, while DMrAC showed higher osmotolerance, decreased sensitivity to Fe and null response to carbendazim or cell wall stress despite similar responses to oxidation and other metal ions.",J WANG 2014,2014,2 genes,Wang-2014-Adenylate cyclase orthologues in two,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4213,PHI:3069,UniProt,E9F4P0,GenBank,EFY97222,,,ARSEF 23,MrAC,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,adenylate cyclase,,,cAMP signalling network,reduced virulence,,,,,median lethal time (LT50)estimates ofDBbACandDMrACagainst susceptible insects were 10.9 and 1.4 d longer than those from wild-type strains respectively,reduced,,reduced,reduced,no,H2O2; menadione; Congo red; carbendazim; NaCl; EDTA; cu2+; mn2+; zn2+; fe3+,"H2O2: CAS:7722-84-1; menadione: CHEBI:28869; Congo red: CHEBI:34653; carbendazim: CHEBI:3392, CAS:10605-21-7; NaCl: CHEBI:26710; EDTA: CHEBI:64758; cu2+: CHEBI:29036; mn2+: CHEBI:29035; zn2+: CHEBI:29105; fe3+: CHEBI:29034",,,,,gene deletion: full; gene complementation,,,RP,24742837,PubMed,10.1016/j.funbio.2014.03.001,,mgfeng@zju.edu.cn,"DBbAC was highly sensitive to oxidation, high osmolarity, cell wall perturbation, carbendazim fungicide, Mn, Zn,Fe, and EDTA but more tolerant to Cu, while DMrAC showed higher osmotolerance, decreased sensitivity to Fe and null response to carbendazim or cell wall stress despite similar responses to oxidation and other metal ions.",J WANG 2014,2014,2 genes,Wang-2014-Adenylate cyclase orthologues in two,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4214,PHI:3070,UniProt,Q2YPI9,GenBank,CAJ10307,,,2308,wadB,,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,glycosyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,fuchsin; thionin; safranin; polymyxin B,fuchsin: CHEBI:75372; thionin: CHEBI:52295; polymyxin B: CHEBI:8309,,,,,gene mutation: characterised; gene complementation,,,RP,24927935,PubMed,10.1016/j.micpath.2014.06.002,,miriart@unav.es,"As compared to wild-typeB. abortus,awadBmutant was sensitive to bactericidal peptides and non-immune serum",Y Gil-Ramírez 2014,2014,1 gene,"Gil-Ramirez-2014-The identification of wadB, a",Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4215,PHI:3071,UniProt,G4Z2B4,GenBank,EGZ19258,,,P6497,PsTatD4,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,nuclease,,,,reduced virulence,,,,,,increased,increased,reduced,,no,H2O2,H2O2: CAS:7722-84-1,,,,,altered gene expression / gene regulation: overexpression,,,RP,2494098,PubMed,10.1094/MPMI-05-14-0153-R,,ddou@njau.edu.cn,"PsTatD4 has DNase activity and is transferred from the cytoplasm to the nucleus upon exposure to H2O2, probably explaining the involvement of PsTatD4 in apoptosis.",L Chen 2014,2014,1 gene,Chen-2014-Phytophthora sojae TatD nuclease pos,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4216,PHI:3072,UniProt,Q2P7T7,GenBank,BAE67390,,,MAFF 311018,StoS,,,,,,,347,Xanthomonas oryzae,342109,pv. oryzae strain MAFF 311018,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,hybrid histidine kinase sensor,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; sorbitol; NaCl,H2O2: CAS:7722-84-1; sorbitol: CHEBI:30911; NaCl: CHEBI:26710,,,,,gene deletion: partial; gene complementation,,,RP,24520898,PubMed,10.1094/MPMI-09-13-0263-R,,s_tsuge@kpu.ac.jp,"Mutants had decreased stress tolerance to high osmolarity, sodium, and H2O2.",Y Ikawa 2014,2014,1 gene,"Ikawa-2014-StoS, a hybrid histidine kinase sen",Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4217,PHI:3073,UniProt,Q9HWS1,GenBank,AE004827_3,,,PAO1,EfhP,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,EF-hand protein involved in Ca2+ homeostasis,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,H2O2; NaCl; ethanol,H2O2: CAS:7722-84-1; NaCl: CHEBI:26710; ethanol: CHEBI:16236,,,,,gene deletion: full; gene complementation,,,RP,24918783,PubMed,10.1371/journal.pone.0098985,,m.patrauchan@okstate.edu,"The mutant strain lost its ability toproduce pyocyanin, developed less biofilm, and had decreased resistance to oxidative stress (H2O2) and reduced virulence when cultured at high[Ca2+].",S A Sarkisova 2014,2014,1 gene,Sarkisova-2014-A Pseudomonas aeruginosa EF-Han,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4218,PHI:3073,UniProt,Q9HWS1,GenBank,AE004827_3,,,PAO1,EfhP,,,,,,,287,Pseudomonas aeruginosa,,FRD1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,EF-hand protein involved in Ca2+ homeostasis,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,H2O2; NaCl; ethanol,H2O2: CAS:7722-84-1; NaCl: CHEBI:26710; ethanol: CHEBI:16236,,,,,gene deletion: full; gene complementation,,,RP,24918783,PubMed,10.1371/journal.pone.0098985,,m.patrauchan@okstate.edu,"The mutant strain lost its ability toproduce pyocyanin, developed less biofilm, and had decreased resistance to oxidative stress (H2O2) and reduced virulence when cultured at high[Ca2+].",S A Sarkisova 2014,2014,1 gene,Sarkisova-2014-A Pseudomonas aeruginosa EF-Han,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4219,PHI:3074,UniProt,D0Z9U0,GenBank,ACY83030,,,EIB202,hupA,,,,,,,636,Edwardsiella tarda,498217,EIB202,hemorrhagic septicemia,bony fishes,7955,Danio rerio (related: zebrafish),,,,muscle; liver; intestine,"nucleoid-associated protein, is a basic DNA-binding protein involved in gene regulation",,,,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl,NaCl: CHEBI:26710,,,,,gene mutation: characterised; gene complementation,,,RP,24793099,PubMed,10.1016/j.vetmic.2014.03.030,,jfxiao@ecust.edu.cn,"Delta hupA mutant was found to be defective in cell growth, H2S production, acid adaptation.",L Wang 2014,2014,1 gene,Wang-2014-HU-induced polymorphous filamentatio,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4220,PHI:3075,UniProt,R4I3H8,GenBank,AFJ04161,,,,PdChsVII,,,,,,,36651,Penicillium digitatum,1170229,isolate PHI26 strain CECT20796,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,chitin synthase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red; H2O2; TBZ; IMZ; SDS,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; H2O2: CAS:7722-84-1; TBZ: CHEBI:45979; SDS: CHEBI:8984,,,,,gene deletion: partial,,,RP,24727399,PubMed,10.1016/j.fgb.2014.04.002,,mgandia@iata.csic.es,"Gene disruption increased susceptibility to antifungal compounds such as calcofluor white (CFW), sodium dodecyl sulfate (SDS), hydroxide peroxide (H2O2) and commercial fungicides, but significantly no change was served in the sensitivity to antifungal peptides.",M Gandía 2014,2014,1 gene,Gandia-2014-The myosin motor domain-containing,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4221,PHI:3076,UniProt,G8BDA6,GenBank,CCE43253,,,CDC317,CpATC1,,,,,,,5480,Candida parapsilosis,,AM2001/0013,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,acid trehalase involved in trehalose hydrolysis,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; NaCl,H2O2: CAS:7722-84-1; NaCl: CHEBI:26710,,,,,gene disruption; gene complementation,,,RP,24922533,PubMed,10.1371/journal.pone.0099113,,arguelle@um.es,"atc1Dnull cells were unable to grow on exogenous trehalose as carbon source, and also displayed higher resistance to environmental challenges, such as saline exposure (1.2 M NaCl), heat shock (42uC) and both mild and severe oxidative stress (5 and 50 mM H2O2).",R Sanchez-Fresneda 2014,2014,1 gene,Sanchez-Fresned-2014-In Candida parapsilosis t,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4222,PHI:3076,UniProt,G8BDA6,GenBank,CCE43253,,,CDC317,CpATC1,,,,,,,5480,Candida parapsilosis,,AM2001/0013,mycosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,acid trehalase involved in trehalose hydrolysis,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; NaCl,H2O2: CAS:7722-84-1; NaCl: CHEBI:26710,,,,,gene disruption; gene complementation,,,RP,24922533,PubMed,10.1371/journal.pone.0099113,,arguelle@um.es,"atc1null cells were unable to grow on exogenous trehalose as carbon source, and also displayed higher resistance to environmental challenges, such as saline exposure (1.2 M NaCl), heat shock (42uC) and both mild and severe oxidative stress (5 and 50 mM H2O2.",R Sanchez-Fresneda 2014,2014,1 gene,Sanchez-Fresned-2014-In Candida parapsilosis t,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4223,PHI:3077,UniProt,P9WIP7,GenBank,CCP46420,,,H37Rv,Lsr2,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,global transcriptional regulator,,,,loss of pathogenicity,,,,,,,,reduced,,no,H2O2; mitomycin C,H2O2: CAS:7722-84-1; mitomycin C: CHEBI:27504,,,,,gene deletion: full; gene complementation,,,RP,24895305,PubMed,10.1128/mBio.01106-14,,martin.voskuil@ucdenver.edu,"The lsr2 mutant did display severe growth defects under normoxic and hyperoxic conditions, but it was not required for growth under low-oxygen conditions. /The lsr2strain is not more sensitive to H2O2 or mitomycin C.",I L Bartek 2014,2014,1 gene,Bartek-2014-Mycobacterium tuberculosis Lsr2 is,Batch039,2014-07-01,MC,,,,,,,,,,,,,
,,Record 4224,PHI:3078,UniProt,C5VVJ6,GenBank,CAR47454,,,P1/7,ssnA,,,,,,,1307,Streptococcus suis,218494,serotype 2 strain P1/7,meningitis; arthritis; endocarditis; septicemia,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),,,,,DNase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24996230,PubMed,10.1186/1756-0500-7-424,,daniel.grenier@greb.ulaval.ca,,B Haas 2014,2014,1 gene,Haas-2014-Characterization of DNase activity a,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4225,PHI:3079,,no data found,BROAD,B0510_2802,,,B05.10,bctrx1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,thioredoxin system,,,,reduced virulence,,no,,,,wild type,wild type,reduced,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,24983673,PubMed,10.1094/MPMI-01-14-0012-R,,tudzyns@uni-muenster.de,Knockout mutants of bctrx1and bctrr1 were severely impaired in virulence and more sensitive to oxidative stress,A Viefhues 2014,2014,5 genes,Viefhues-2014-Redox Systems in Botrytis cinere,Batch040,2014-08-01,MC,"Could not find Ids that correspond to the Ids mentioned by the author. Retained as is, because could not differentiate between the similar genes",,,,,,,,,,,,
,,Record 4226,PHI:3080,,no data found,BROAD,B0510_928,,,B05.10,bctrx2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,thioredoxin system,,,,unaffected pathogenicity,,no,,,,wild type,wild type,,wild type,no,,,,,,,gene disruption; gene complementation,,,RP,24983673,PubMed,10.1094/MPMI-01-14-0012-R,,tudzyns@uni-muenster.de,Knockout mutants of bctrx1and bctrr1 were severely impaired in virulence and more sensitive to oxidative stress,A Viefhues 2014,2014,5 genes,Viefhues-2014-Redox Systems in Botrytis cinere,Batch040,2014-08-01,MC,"Could not find Ids that correspond to the Ids mentioned by the author. Retained as is, because could not differentiate between the similar genes",,,,,,,,,,,,
,,Record 4227,PHI:3081,,no data found,BROAD,B0510_1511,,,B05.10,bctrr1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,thioredoxin system,,,,reduced virulence,,no,,,,wild type,wild type,reduced,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,24983673,PubMed,10.1094/MPMI-01-14-0012-R,,tudzyns@uni-muenster.de,Knockout mutants of bctrx1and bctrr1 were severely impaired in virulence and more sensitive to oxidative stress,A Viefhues 2014,2014,5 genes,Viefhues-2014-Redox Systems in Botrytis cinere,Batch040,2014-08-01,MC,"Could not find Ids that correspond to the Ids mentioned by the author. Retained as is, because could not differentiate between the similar genes",,,,,,,,,,,,
,,Record 4228,PHI:3079,,no data found,BROAD,B0510_2802,,,B05.10,bctrx1,,,,,,PHI:3081,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,thioredoxin system,,,,reduced virulence,,no,,,,wild type,wild type,reduced,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,24983673,PubMed,10.1094/MPMI-01-14-0012-R,,tudzyns@uni-muenster.de,Knockout mutants of bctrx1and bctrr1 were severely impaired in virulence and more sensitive to oxidative stress,A Viefhues 2014,2014,5 genes,Viefhues-2014-Redox Systems in Botrytis cinere,Batch040,2014-08-01,MC,"Could not find Ids that correspond to the Ids mentioned by the author. Retained as is, because could not differentiate between the similar genes",,,,,,,,,,,,
,,Record 4229,PHI:3081,,no data found,BROAD,B0510_1511,,,B05.10,bctrr1,,,,,,PHI:3079,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,thioredoxin system,,,,reduced virulence,,no,,,,wild type,wild type,reduced,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,24983673,PubMed,10.1094/MPMI-01-14-0012-R,,tudzyns@uni-muenster.de,Knockout mutants of bctrx1and bctrr1 were severely impaired in virulence and more sensitive to oxidative stress,A Viefhues 2014,2014,5 genes,Viefhues-2014-Redox Systems in Botrytis cinere,Batch040,2014-08-01,MC,"Could not find Ids that correspond to the Ids mentioned by the author. Retained as is, because could not differentiate between the similar genes",,,,,,,,,,,,
,,Record 4230,PHI:3082,,no data found,BROAD,B0510_2036,,,B05.10,bcglr1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,glutathione reductase,,,,reduced virulence,,no,,,,wild type,wild type,reduced,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,24983673,PubMed,10.1094/MPMI-01-14-0012-R,,tudzyns@uni-muenster.de,Knockout mutants of bctrx1and bctrr1 were severely impaired in virulence and more sensitive to oxidative stress,A Viefhues 2014,2014,5 genes,Viefhues-2014-Redox Systems in Botrytis cinere,Batch040,2014-08-01,MC,"Could not find Ids that correspond to the Ids mentioned by the author. Retained as is, because could not differentiate between the similar genes",,,,,,,,,,,,
,,Record 4231,PHI:3083,,no data found,BROAD,B0510_1402,,,B05.10,bcglr2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,glutathione reductase,,,,unaffected pathogenicity,,no,,,,wild type,wild type,wild type,wild type,no,,,,,,,gene disruption; gene complementation,,,RP,24983673,PubMed,10.1094/MPMI-01-14-0012-R,,tudzyns@uni-muenster.de,Knockout mutants of bctrx1and bctrr1 were severely impaired in virulence and more sensitive to oxidative stress,A Viefhues 2014,2014,5 genes,Viefhues-2014-Redox Systems in Botrytis cinere,Batch040,2014-08-01,MC,"Could not find Ids that correspond to the Ids mentioned by the author. Retained as is, because could not differentiate between the similar genes",,,,,,,,,,,,
,,Record 4232,PHI:3084,UniProt,A3M771,GenBank,ABO12765,,,ATCC 17978,A1S_2343,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,superoxide dismutase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25000585,PubMed,10.1371/journal.pone.0101033,,wilharmg@rki.de,"The mutant strains were more susceptible to oxidative stress compared to their parental strains. Susceptibility to colistin and tetracycline was increased in all mutant strains while susceptibility of the mutants to gentamicin, levofloxacin and imipenem was strain-dependent. / Growth depends on aeration.",M Heindorf 2014,2014,1 gene,Heindorf-2014-Impact of Acinetobacter baumanni,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4233,PHI:3085,UniProt,P42375,GenBank,BAA04222,,,FDC 381,GroEL,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,gingiva,"folding of newly synthesized proteins, preventing misfolding and aggregation",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,25058444,PubMed,10.1371/journal.pone.0102450,,ywlin@ym.edu.tw,,F Lin 2014,2014,1 gene,Lin-2014-Porphyromonas gingivalis GroEL Induce,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4234,PHI:3086,UniProt,Q49GQ5,GenBank,AAX99101,,,HP88,prtA,,,,,,,29488,Photorhabdus luminescens,,158-S-2,septicemia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,encodes the virulence factor protease A,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,25036004,PubMed,10.1016/j.jip.2014.07.001,,AHBishop@dstl.gov.uk,"There was no difference in the speed or level of mortality when spores andd-endotoxins crystals of the transformed strain were fed to larvae ofPieris brassicae, as compared to the wild-type strain. When vegetative cells were injected into the hemocoel of larvae of Galleria mellonella, however, there was a significant increase in the rate and level of mortality in the wild type.",A H Bishop 2014,2014,1 gene,Bishop-2014-Expression of prtA from Photorhabd,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4235,PHI:3087,UniProt,I1RSW5,GenBank,ESU13482,,,PH-1,CPK1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,encode the catalytic subunits of cyclic AMP (cAMP)-dependent protein kinase A (PKA),,,,reduced virulence,,yes,,yes,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24450772,PubMed,10.1094/MPMI-10-13-0306-R,,jinrong@purdue.edu,,S Hu 2014,2014,3 genes,"Hu-2014-The cAMP-PKA pathway regulates growth,",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4236,PHI:3088,UniProt,I1RWQ0,GenBank,ESU14577,,,PH-1,CPK2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,encode the catalytic subunits of cyclic AMP (cAMP)-dependent protein kinase A (PKA),,,,unaffected pathogenicity,,no,,no,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24450772,PubMed,10.1094/MPMI-10-13-0306-R,,jinrong@purdue.edu,,S Hu 2014,2014,3 genes,"Hu-2014-The cAMP-PKA pathway regulates growth,",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4237,PHI:3089,UniProt,A0A098D2Y5,EMBL,FGRAMPH1_01T03055,,,PH-1,fac1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,adenylate cyclase,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24450772,PubMed,10.1094/MPMI-10-13-0306-R,,jinrong@purdue.edu,,S Hu 2014,2014,3 genes,"Hu-2014-The cAMP-PKA pathway regulates growth,",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4238,PHI:3087,UniProt,I1RSW5,GenBank,ESU13482,,,PH-1,CPK1,,,,,,PHI:3088,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,encode the catalytic subunits of cyclic AMP (cAMP)-dependent protein kinase A (PKA),,,,loss of pathogenicity,,yes,,yes,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24450772,PubMed,10.1094/MPMI-10-13-0306-R,,jinrong@purdue.edu,,S Hu 2014,2014,3 genes,"Hu-2014-The cAMP-PKA pathway regulates growth,",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4239,PHI:3088,UniProt,I1RWQ0,GenBank,ESU14577,,,PH-1,CPK2,,,,,,PHI:3087,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,encode the catalytic subunits of cyclic AMP (cAMP)-dependent protein kinase A (PKA),,,,loss of pathogenicity,,yes,,yes,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24450772,PubMed,10.1094/MPMI-10-13-0306-R,,jinrong@purdue.edu,,S Hu 2014,2014,3 genes,"Hu-2014-The cAMP-PKA pathway regulates growth,",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4240,PHI:3087,UniProt,I1RSW5,GenBank,ESU13482,,,PH-1,CPK1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,spikelet,encode the catalytic subunits of cyclic AMP (cAMP)-dependent protein kinase A (PKA),,,,reduced virulence,,yes,,yes,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24450772,PubMed,10.1094/MPMI-10-13-0306-R,,jinrong@purdue.edu,,S Hu 2014,2014,3 genes,"Hu-2014-The cAMP-PKA pathway regulates growth,",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4241,PHI:3088,UniProt,I1RWQ0,GenBank,ESU14577,,,PH-1,CPK2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,spikelet,encode the catalytic subunits of cyclic AMP (cAMP)-dependent protein kinase A (PKA),,,,unaffected pathogenicity,,no,,no,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24450772,PubMed,10.1094/MPMI-10-13-0306-R,,jinrong@purdue.edu,,S Hu 2014,2014,3 genes,"Hu-2014-The cAMP-PKA pathway regulates growth,",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4242,PHI:3089,UniProt,A0A098D2Y5,EMBL,FGRAMPH1_01T03055,,,PH-1,fac1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,spikelet,adenylate cyclase,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24450772,PubMed,10.1094/MPMI-10-13-0306-R,,jinrong@purdue.edu,,S Hu 2014,2014,3 genes,"Hu-2014-The cAMP-PKA pathway regulates growth,",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4243,PHI:3087,UniProt,I1RSW5,GenBank,ESU13482,,,PH-1,CPK1,,,,,,PHI:3088,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,spikelet,encode the catalytic subunits of cyclic AMP (cAMP)-dependent protein kinase A (PKA),,,,loss of pathogenicity,,yes,,yes,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24450772,PubMed,10.1094/MPMI-10-13-0306-R,,jinrong@purdue.edu,,S Hu 2014,2014,3 genes,"Hu-2014-The cAMP-PKA pathway regulates growth,",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4244,PHI:3088,UniProt,I1RWQ0,GenBank,ESU14577,,,PH-1,CPK2,,,,,,PHI:3087,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,spikelet,encode the catalytic subunits of cyclic AMP (cAMP)-dependent protein kinase A (PKA),,,,loss of pathogenicity,,yes,,yes,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24450772,PubMed,10.1094/MPMI-10-13-0306-R,,jinrong@purdue.edu,,S Hu 2014,2014,3 genes,"Hu-2014-The cAMP-PKA pathway regulates growth,",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4245,PHI:3090,UniProt,V9W6M6,GenBank,AHD05614,,,DSM 25430,pamA,,,,,,,1464,Paenibacillus larvae,697284,subsp. larvae strain DSM 25430,American foulbrood,bees,7460,Apis mellifera (related: honey bee),,,,larva,"encodes paenilamicin, a secondary metabolite antibiotic",,,,reduced virulence,,yes,,yes,,wild type,wild type,,,no,,,,,,,gene disruption,,,RP,25044543,PubMed,10.1002/mbo3.195,,elke.genersch@rz.hu-berlin.de,"Bee larvae infected with the nonproducing Pam strain showed no decrease in larval mortality, but a delay in the onset of larval death.",E Garcia-Gonzalez 2014,2014,1 gene,Garcia-Gonzalez-2014-Biological effects of pae,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4246,PHI:3091,UniProt,H3RJ93,GenBank,EHT98350,,,DC283,OxyR,,,,,,,66269,Pantoea stewartii,660596,subsp. stewartii strain DC283,Stewart's wilt,monocots,4577,Zea mays (related: maize),cv. Jubilee,,,leaf,activate gene expression in response to oxidative stress,,,,unaffected pathogenicity,,no,,,,,,,,no,,,,,,,gene mutation,,,RP,24450773,PubMed,10.1094/MPMI-11-13-0348-R,,mcroper@ucr.edu,,L Burbank 2014,2014,2 genes,Burbank-2014-OxyR and SoxR modulate the induci,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4247,PHI:3092,UniProt,H3RI38,GenBank,EHT98951,,,DC283,SoxR,,,,,,,66269,Pantoea stewartii,660596,subsp. stewartii strain DC283,Stewart's wilt,monocots,4577,Zea mays (related: maize),cv. Jubilee,,,leaf,activate gene expression in response to oxidative stress,,,,reduced virulence,,yes,,,,,,,,no,,,,,,,gene mutation,,,RP,24450773,PubMed,10.1094/MPMI-11-13-0348-R,,mcroper@ucr.edu,,L Burbank 2014,2014,2 genes,Burbank-2014-OxyR and SoxR modulate the induci,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4248,PHI:3093,UniProt,B5UAE3,GenBank,BAG74779,,,MNCM07,Sbp2,,,,,,,1307,Streptococcus suis,218494,serotype 2 strain P1/7,meningitis; arthritis; endocarditis; septicemia,bony fishes,7955,Danio rerio (related: zebrafish),,,,,involved in pili production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24989484,PubMed,10.1007/s00284-014-0642-4,,ucp@njau.edu.cn,,J Shao 2014,2014,1 gene,Shao-2014-The Truncated Major Pilin Subunit Sb,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4249,PHI:3094,,no data found,,EJP701002,,,,Bbmsn2,,,,,,,176275,Beauveria bassiana,,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,involved in pH-dependent negative regulator ofsecondary metabolite production,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24965521,PubMed,10.1111/1462-2920.12542,,keyhani@ufl.edu,,Z Luo 2014,2014,1 gene,Luo-2014-Bbmsn2 acts as a pH-dependent negativ,Batch040,2014-08-01,MC,"Could not find Ids that correspond to the Ids mentioned by the author. Retained as is, because could not differentiate between the similar genes",,,,,,,,,,,,
,,Record 4250,PHI:3095,UniProt,J5JDI1,GenBank,EJP63998,,,ARSEF 2860,Ktr1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glycolipid 2-alpha-mannosyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,24981201,PubMed,10.1016/j.fgb.2014.06.010,,mgfeng@zju.edu.cn,Dktr4 and Dkre2 became more sensitive to oxidation and cell wall perturbation than Dktr1during colony growth or conidial germination.,J Wang 2014,2014,3 genes,"Wang-2014-Three alpha-1,2-mannosyltransferases",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4251,PHI:3096,UniProt,J5K093,GenBank,EJP69973,,,ARSEF 2860,Ktr4,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glycosyltransferase family 15,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,24981201,PubMed,10.1016/j.fgb.2014.06.010,,mgfeng@zju.edu.cn,Dktr4 and Dkre2 became more sensitive to oxidation and cell wall perturbation than Dktr1during colony growth or conidial germination.,J Wang 2014,2014,3 genes,"Wang-2014-Three alpha-1,2-mannosyltransferases",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4252,PHI:3097,UniProt,J5JEX5,GenBank,EJP62226,,,ARSEF 2860,Kre2/Mnt1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glycolipid 2-alpha-mannosyltransferase,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,24981201,PubMed,10.1016/j.fgb.2014.06.010,,mgfeng@zju.edu.cn,Dktr4 and Dkre2 became more sensitive to oxidation and cell wall perturbation than Dktr1during colony growth or conidial germination.,J Wang 2014,2014,3 genes,"Wang-2014-Three alpha-1,2-mannosyltransferases",Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4253,PHI:3098,UniProt,J9VJS8,GenBank,AFR92864,,,H99,URA4,,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcal meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,dihydroorotase (DHOase),,,pyrimidine biosynthetic pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,25011011,PubMed,10.1016/j.fgb.2014.06.003,,marcelo.vallim@unifesp.br,The mutants show high temperature growth defect.,F A Gontijo 2014,2014,1 gene,de Gontijo-2014-The role of the de novo pyrimi,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4254,PHI:3099,UniProt,K4NK05,GenBank,AFV38816,,,A20,htpA,,,,,,,1314,Streptococcus pyogenes,1235829,A-20,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,acid-induced protein histidine triad protein and virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24998435,PubMed,10.1016/j.jprot.2014.06.026,,jjwu@mail.ncku.edu.tw,,Y Wen 2014,2014,1 gene,Wen-2014-Label-free proteomic analysis of envi,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4255,PHI:3100,,no data found,JGI,Crypa1.estExt_fgenesh1_kg.C_50131,,,,Prb1,,,,,,,5116,Cryphonectria parasitica,660469,EP155,blight (chestnut),eudicots,60419,Castanea mollissima (related: chinese chestnut),,,,stem,subtilisin-like protease involved in virulence,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25066598,PubMed,10.1111/1574-6968.12547,,chenyaoj@gxu.edu.cn,,L Shi 2014,2014,1 gene,"Shi-2014-Prb1, a subtilisin-like protease, is",Batch040,2014-08-01,MC,extra info source: http://genomeportal.jgi-psf.org/pages/search-for-genes.jsf?organism=Crypa2,,,,,,,,,,,,
,,Record 4256,PHI:3101,UniProt,Q8IEJ6,GenBank,CAD52260,,,3D7,BCKDH,chromosome 13,,,,,,5833,Plasmodium falciparum,,ANKA,malaria,primates,9606,Homo sapiens (related: human),,,,,ketoacid dehydrogenase (BCKDH) complex,,,mitochondrial tricarboxylic acid (TCA) cycle,reduced virulence,,,,,,,reduced,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25032958,PubMed,10.1371/journal.ppat.1004263,,Dominique.Soldati-Favre@unige.ch,,R D Oppenheim 2014,2014,2 genes,Oppenheim-2014-BCKDH_ The Missing Link in Apic,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4257,PHI:3102,UniProt,Q1KSF2,GenBank,ABE76505,,,RH,BCKDH,chromosome 6,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,ketoacid dehydrogenase (BCKDH) complex,,,mitochondrial tricarboxylic acid (TCA) cycle,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25032958,PubMed,10.1371/journal.ppat.1004263,,Dominique.Soldati-Favre@unige.ch,,R D Oppenheim 2014,2014,2 genes,Oppenheim-2014-BCKDH_ The Missing Link in Apic,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4258,PHI:3103,UniProt,C4B8B9,,AB916599,,,,Pex31-A,,,,,,,318829,Magnaporthe oryzae,,84R-62B,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Kanto 51,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25056242,PubMed,10.1007/s00294-014-0437-y,,mkusaba@cc.saga-u.ac.jp,,M Kusaba 2014,2014,2 genes,Kusaba-2014-Loss of a 1.6 Mb chromosome in Pyr,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4259,PHI:3104,UniProt,C4B8B8,,AB916598,,,,Pex31-D,,,,,,,318829,Magnaporthe oryzae,,84R-62B,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Kanto 51,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25056242,PubMed,10.1007/s00294-014-0437-y,,mkusaba@cc.saga-u.ac.jp,,M Kusaba 2014,2014,2 genes,Kusaba-2014-Loss of a 1.6 Mb chromosome in Pyr,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4260,PHI:3105,UniProt,Q8Y9V8,GenBank,CAC98491,,,EGD-e,Lmo0412,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,membrane protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25051038,PubMed,10.1016/j.micinf.2014.07.002,,mg.pucciarelli@uam.es,,J Jquereda 2014,2014,1 gene,Quereda-2014-Deletion of the membrane protein,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4261,PHI:3106,UniProt,P27243,GenBank,AAA24524,,,K-12,waaL,,,,,,,562,Escherichia coli,,DE17,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,encodes O-antigen ligase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,24970366,PubMed,10.1016/j.vetmic.2014.05.02,,yus@shvri.ac.cn,,Y Han 2014,2014,1 gene,Han-2014-The waaL gene is involved in lipopoly,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4262,PHI:3107,UniProt,B0RY65,GenBank,CAP52585,,,B100,RavA,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24970366,PubMed,10.1016/j.vetmic.2014.05.029,,czhe@hainu.edu.cn,,J Tao 2014,2014,1 gene,Tao-2014-RavA_RavR two-component system regula,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4263,PHI:3108,UniProt,B0RPP4,GenBank,CAP50429,,,B100,RavR,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,bifunctional enzyme involved in c-di-GMP synthesis and degradation,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24970366,PubMed,10.1016/j.vetmic.2014.05.029,,czhe@hainu.edu.cn,,J Tao 2014,2014,1 gene,Tao-2014-RavA_RavR two-component system regula,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4264,PHI:3109,UniProt,I1RQL4,GenBank,ESU12445,,,PH-1,FgSKN7,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,stress-related transcription factor gene,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25040476,PubMed,10.1111/1462-2920.12561,,jinrong@purdue.edu,,C Jiang 2014,2014,3 genes,Jiang-2014-FgSKN7 and FgATF1have overlapping f,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4265,PHI:3110,UniProt,I1S0C0,GenBank,ESU16819,,,PH-1,FgATF1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,stress-related transcription factor gene,,,,reduced virulence,,,,yes,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25040476,PubMed,10.1111/1462-2920.12561,,jinrong@purdue.edu,,C Jiang 2014,2014,3 genes,Jiang-2014-FgSKN7 and FgATF1have overlapping f,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4266,PHI:3111,UniProt,I1RWW4,GenBank,ESU14495,,,PH-1,FgAP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,stress-related transcription factor gene,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25040476,PubMed,10.1111/1462-2920.12561,,jinrong@purdue.edu,,C Jiang 2014,2014,3 genes,Jiang-2014-FgSKN7 and FgATF1have overlapping f,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4267,PHI:3109,UniProt,I1RQL4,GenBank,ESU12445,,,PH-1,FgSKN7,,,,,,PHI:3110,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,stress-related transcription factor gene,,,,reduced virulence,,,,yes,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25040476,PubMed,10.1111/1462-2920.12561,,jinrong@purdue.edu,,C Jiang 2014,2014,3 genes,Jiang-2014-FgSKN7 and FgATF1have overlapping f,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4268,PHI:3110,UniProt,I1S0C0,GenBank,ESU16819,,,PH-1,FgATF1,,,,,,PHI:3109,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,stress-related transcription factor gene,,,,reduced virulence,,,,yes,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25040476,PubMed,10.1111/1462-2920.12561,,jinrong@purdue.edu,,C Jiang 2014,2014,3 genes,Jiang-2014-FgSKN7 and FgATF1have overlapping f,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4269,PHI:3111,UniProt,I1RWW4,GenBank,ESU14495,,,PH-1,FgAP1,,,,,,PHI:3109,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,stress-related transcription factor gene,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25040476,PubMed,10.1111/1462-2920.12561,,jinrong@purdue.edu,,C Jiang 2014,2014,3 genes,Jiang-2014-FgSKN7 and FgATF1have overlapping f,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4270,PHI:3109,UniProt,I1RQL4,GenBank,ESU12445,,,PH-1,FgSKN7,,,,,,PHI:3111,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,stress-related transcription factor gene,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25040476,PubMed,10.1111/1462-2920.12561,,jinrong@purdue.edu,,C Jiang 2014,2014,3 genes,Jiang-2014-FgSKN7 and FgATF1have overlapping f,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4271,PHI:3111,UniProt,I1RWW4,GenBank,ESU14495,,,PH-1,FgAP1,,,,,,PHI:3110,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,stress-related transcription factor gene,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25040476,PubMed,10.1111/1462-2920.12561,,jinrong@purdue.edu,,C Jiang 2014,2014,3 genes,Jiang-2014-FgSKN7 and FgATF1have overlapping f,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4272,PHI:3110,UniProt,I1S0C0,GenBank,ESU16819,,,PH-1,FgATF1,,,,,,PHI:3111,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,stress-related transcription factor gene,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25040476,PubMed,10.1111/1462-2920.12561,,jinrong@purdue.edu,,C Jiang 2014,2014,3 genes,Jiang-2014-FgSKN7 and FgATF1have overlapping f,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4273,PHI:3112,UniProt,Q8P8Q1,GenBank,AAM41468,,,ATCC 33913,galU,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,uridine triphosphate (UTP)-glucose-1-phosphate uridylyltransferase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25033927,PubMed,10.1007/s00203-014-1012-0,,ymhsiao@ctust.edu.tw,,C Liao 2014,2014,1 gene,Liao-2014-The galU gene of Xanthomonas campest,Batch040,2014-08-01,MC,,,,,,,,,,,,,
,,Record 4274,PHI:3113,UniProt,F4MD99,GenBank,AEE60096,,,UMNK88,stbA,plasmid pRS218,RS218:pRS218deltastbA::cat (mutants of the plasmid gene StbA fused to chloramphenicol resistance cassette),,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,blood; cerebrospinal fluid; brain,stability protein for the plasmid,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,"mutants were electroporated toE. coliRS218 carrying the red helper plasmid, pKD119",,RP,25164788,PubMed,10.1186/s12866-014-0203-9,BMC Microbiol. 2014 Aug 28;14(1):203,sxk91@psu.edu,The plasmid carries many genes and was cured by mutating the stability gene to check for the effect of the absence of the entire plasmid,D S S Wijetunge 2014,2014,1 gene,Wijetunge-2014-Complete nucleotide sequence of,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4275,PHI:3114,UniProt,N0A4X7,GenBank,AGK45292,,,SA18,FrxA,,deltaFrxA::kan (mutants of the plasmid gene FrxA fused to kanamycin resistance cassette),,,,,210,Helicobacter pylori,85962,26695,gastric infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,stomach,NADH-flavin oxidoreductase,,,,reduced virulence,,,,,,,,,,no,S-nitrosoglutathione (GSNO),S-nitrosoglutathione (GSNO): CHEBI:50091,,,,,gene mutation: characterised; gene complementation,,,RP,25132107,PubMed,10.1111/febs.12958,FEBS J. 2014 Aug 6,lst@itqb.unl.pt,,M C Justino 2014,2014,1 gene,Justino-2014-FrxA is an S-nitrosoglutathione r,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4276,PHI:3115,UniProt,Q88BW6,GenBank,AAO59098,,,DC3000,PSPTO_5633,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4277,PHI:3116,UniProt,Q88AL8,GenBank,AAO53915,,,DC3000,PSPTO_0371,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,indoleacetate-lysine ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4278,PHI:3117,UniProt,Q884G3,GenBank,AAO55647,,,DC3000,PSPTO_2130,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,DNA-binding response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4279,PHI:3118,UniProt,Q882D7,GenBank,AAO56193,,,DC3000,PSPTO_2691,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,"membrane protein, TerC family",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4280,PHI:3119,UniProt,Q882D2,GenBank,AAO56198,,,DC3000,PSPTO_2696,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,MutT/nudix family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4281,PHI:3120,UniProt,Q87ZU3,GenBank,AAO56809,,,DC3000,PSPTO_3331,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,alkaline proteinase inhibitor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4282,PHI:3121,UniProt,Q87UQ6,GenBank,AAO58666,,,DC3000,PSPTO_5240,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,"oxidoreductase, iron-sulfur-binding protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4283,PHI:3115,UniProt,Q88BW6,GenBank,AAO59098,,,DC3000,PSPTO_5633,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4284,PHI:3116,UniProt,Q88AL8,GenBank,AAO53915,,,DC3000,PSPTO_0371,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,indoleacetate-lysine ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4285,PHI:3117,UniProt,Q884G3,GenBank,AAO55647,,,DC3000,PSPTO_2130,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,DNA-binding response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4286,PHI:3118,UniProt,Q882D7,GenBank,AAO56193,,,DC3000,PSPTO_2691,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,"membrane protein, TerC family",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4287,PHI:3119,UniProt,Q882D2,GenBank,AAO56198,,,DC3000,PSPTO_2696,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,MutT/nudix family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4288,PHI:3120,UniProt,Q87ZU3,GenBank,AAO56809,,,DC3000,PSPTO_3331,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,alkaline proteinase inhibitor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4289,PHI:3121,UniProt,Q87UQ6,GenBank,AAO58666,,,DC3000,PSPTO_5240,,PSPTO_5633::Cya (translocation reporter geneadenylate cyclase was fused to the C terminus of PSPTO_5633);,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,"oxidoreductase, iron-sulfur-binding protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation,,,RP,25170934,PubMed,10.1371/journal.pone.0106115,PLoS One. 2014 Aug 29;9(8):e106115,sam.cartinhour@ars.usda.gov,"PSPTO_5633 appears to be a weak Type III secretion effector. Since PSPTO_5633 translocates poorly in DC3000, its translocation may be undetectable inP. fluorescens.",H N Lam 2014,2014,7 genes,Lam-2014-Global Analysis of the HrpL Regulon i,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4290,PHI:3122,UniProt,G5EI17,GenBank,EAQ71199,,,70-15,MC69,chromosome 7,MC69p::mCherry (MC69promoter fused with a reporter protein gene mCherry),,,,,318829,Magnaporthe oryzae,,Ina72,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Shin 2,,,leaf,effector protein,,,,effector (plant avirulence determinant),,no,yes,yes,,wild type,,wild type,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation: characterised,,,RP,22589729,PubMed,10.1371/journal.ppat.1002711,PLoS Pathog. 2012;8(5):e1002711,saitoh@ibrc.or.jp,,H Saitoh 2012,2012,2 genes,Saitoh-2012-Large-scale gene disruption in Mag,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4291,PHI:3122,UniProt,G5EI17,GenBank,EAQ71199,,,70-15,MC69,chromosome 7,MC69p::mCherry (MC69promoter fused with a reporter protein gene mCherry),,,,,318829,Magnaporthe oryzae,,Ina72,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Nigrate,,,leaf,effector protein,,,,effector (plant avirulence determinant),,no,yes,yes,,wild type,,wild type,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation: characterised,,,RP,22589729,PubMed,10.1371/journal.ppat.1002711,PLoS Pathog. 2012;8(5):e1002711,saitoh@ibrc.or.jp,,H Saitoh 2012,2012,2 genes,Saitoh-2012-Large-scale gene disruption in Mag,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4292,PHI:3123,UniProt,H7CE70,GenBank,BAL70272,,,104-T,CoMC69,,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,no,yes,yes,,wild type,,wild type,,no,,,,,,deletions do not affect the hypersensitive response orin planta growth of the resulting strains,gene mutation: characterised,,,RP,22589729,PubMed,10.1371/journal.ppat.1002711,PLoS Pathog. 2012;8(5):e1002711,saitoh@ibrc.or.jp,,H Saitoh 2012,2012,2 genes,Saitoh-2012-Large-scale gene disruption in Mag,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4293,PHI:3124,UniProt,A9JX75,GenBank,EDP89767,,,SN15,SnTox1,chromosome 1BS,,,,,,13684,Parastagonospora nodorum,,Sn2000,Stagonospora nodorum blotch (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. W-7984,Snn1,UniProt: W5I2V6,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptibility,,gene mutation,,,RP,22241993,PubMed,10.1371/journal.ppat.1002467,PLoS Pathog. 2012 Jan;8(1):e1002467,timothy.friesen@ars.usda.gov,"The transformation ofSnTox1into an avirulent S. nodorumisolate was sufficient to make the strain pathogenic. Additionally, the deletion ofSnTox1 in virulent isolates rendered the SnTox1 mutated strains avirulent on theSnn1 differential wheat line.",Z Liu 2012,2012,1 gene,Liu-2012-The cysteine rich necrotrophic effect,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4294,PHI:3125,UniProt,Q9RQU7,GenBank,AF065259_1,,,79-685,Flagellin,,,,,,,1496,Clostridioides difficile,272563,630,enteric disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,gastrointestinal tract,motility,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25135277,PubMed,10.1111/mmi.12755,Mol Microbiol. 2014 Aug 18,Brendan.wren@lshtm.ac.uk,mutation in flagellin lead to changes in post translational modification which seem to control virulence. Pathogen formerly called Clostridium difficile,A Faulds-Pain 2014,2014,1 gene,Faulds-Pain-2014-The post-translational modifi,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4295,PHI:3126,UniProt,D4I307,GenBank,CBA23647,,,CFBP1430,argD,,argD1000::Tn5 (mutant was named argD1000::Tn5 because the Tn5transposon was inserted after the 129 argD gene coding region nucleotide number 999),,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot; fruit,argDgene encodes a predicted N-acetylornithine aminotransferase enzyme,,,arginine pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25172854,PubMed,10.1128/AEM.02404-14,Appl Environ Microbiol. 2014 Aug 29. pii: AEM.02404-14.,twm4@psu.edu,The argD1000::Tn5mutant did not grow in M9 minimal media supplemented with thiamine and nicotinic acid (M9TN) media with sorbitolas the carbon source,L S Ramos 2014,2014,1 gene,Ramos-2014-Mutation of the Erwinia amylovora a,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4296,PHI:3126,UniProt,D4I307,GenBank,CBA23647,,,CFBP1430,argD,,argD1000::Tn5 (mutant was named argD1000::Tn5 because the Tn5transposon was inserted after the 129 argD gene coding region nucleotide number 999),,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bosc,,,shoot; fruit,argDgene encodes a predicted N-acetylornithine aminotransferase enzyme,,,arginine pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25172854,PubMed,10.1128/AEM.02404-14,Appl Environ Microbiol. 2014 Aug 29. pii: AEM.02404-14.,twm4@psu.edu,The argD1000::Tn5mutant did not grow in M9 minimal media supplemented with thiamine and nicotinic acid (M9TN) media with sorbitolas the carbon source,L S Ramos 2014,2014,1 gene,Ramos-2014-Mutation of the Erwinia amylovora a,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4297,PHI:3127,UniProt,B2C3H8,GenBank,ABZ03962,,,,MpCP1,,,,,,,153609,Moniliophthora perniciosa,,CP02,Witches' broom,eudicots,3641,Theobroma cacao (related: cacao),,,,pod,cerato-platanin (CP)-like proteins,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,necrosis,functional test in host: transient expression,,,RP,18796332,PubMed,10.1016/j.mycres.2008.08.004,Mycol Res. 2009 Jan;113(Pt 1):61-72,goncalo@unicamp.br,,G ZAPAROLI 2009,2009,2 genes,Zaparoli-2009-Identification of a second famil,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4298,PHI:3127,UniProt,B2C3H8,GenBank,ABZ03962,,,,MpCP1,,,,,,,153609,Moniliophthora perniciosa,,CP02,Witches' broom,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,cerato-platanin (CP)-like proteins,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,"transparency, dried leaf",functional test in host: direct injection,,,RP,18796332,PubMed,10.1016/j.mycres.2008.08.004,Mycol Res. 2009 Jan;113(Pt 1):61-72,goncalo@unicamp.br,,G ZAPAROLI 2009,2009,2 genes,Zaparoli-2009-Identification of a second famil,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4299,PHI:3127,UniProt,B2C3H8,GenBank,ABZ03962,,,,MpCP1,,,,,,PHI:3128,153609,Moniliophthora perniciosa,,CP02,Witches' broom,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,cerato-platanin (CP)-like proteins,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,a mixture of mpCP1 with mpNEP2 led to a synergistic necrosis effect very similar to that found in naturally infected plants,functional test in host: direct injection,,,RP,18796332,PubMed,10.1016/j.mycres.2008.08.004,Mycol Res. 2009 Jan;113(Pt 1):61-72,goncalo@unicamp.br,,G ZAPAROLI 2009,2009,2 genes,Zaparoli-2009-Identification of a second famil,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4300,PHI:3128,UniProt,A5H7H0,GenBank,ABO32369,,,,MpNEP2,,,,,,PHI:3127,153609,Moniliophthora perniciosa,,CP02,Witches' broom,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,necrosis-and ethylene-inducing protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,a mixture of mpCP1 with mpNEP2 led to a synergistic necrosis effect very similar to that found in naturally infected plants,functional test in host: direct injection,,,RP,18796332,PubMed,10.1016/j.mycres.2008.08.004,Mycol Res. 2009 Jan;113(Pt 1):61-72,goncalo@unicamp.br,,G ZAPAROLI 2009,2009,2 genes,Zaparoli-2009-Identification of a second famil,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4301,PHI:3129,UniProt,Q3BP62,GenBank,CAJ25451,,,85-10,wxcB,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4081,Solanum lycopersicum (related: tomato),cv. VF36,,,leaf,"the function of wxcBin the LPS biosynthesis cluster is related to the regulation of virulence, motility, biofilm formation, and SDS tolerance, but not LPS synthesis",,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene disruption; gene complementation,,,RP,25159842,PubMed,10.1016/j.bbrc.2014.08.076,Biochem Biophys Res Commun. 2014 Aug 23. pii: S0006-291X(14)01499-5,swhan@cau.ac.kr,"The mutant displayed reduced motility and tolerance to treatment, but it showed increased biofilm formation. Interestingly, the LPS profile was unchanged.",H Park 2014,2014,1 gene,Park-2014-Functional and proteomic analyses re,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4302,PHI:3130,UniProt,G0X840,GenBank,AEK86931,,,RK123,Tin2,,,,ZmTTK1,UniProt: B6SYS4,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,anthocyanin biosynthesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptibility,,functional test in host: transient expression,Agrobacterium tumefaciens GV3101 strains carrying expression plasmids indicated in each experiment were grown in YT medium containing kanamycin,,RP,24473076,PubMed,10.7554/eLife.01355,Elife. 2014;3:e01355,kahmann@mpi-marburg.mpg.de,,S Tanaka 2014,2014,1 gene,Tanaka-2014-A secreted Ustilago maydis effecto,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4303,PHI:3130,UniProt,G0X840,GenBank,AEK86931,,,RK123,Tin2,,,,ZmTTK1,UniProt: B6SYS4,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,anthocyanin biosynthesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptibility,,gene disruption,,,RP,24473076,PubMed,10.7554/eLife.01355,Elife. 2014;3:e01355,kahmann@mpi-marburg.mpg.de,,S Tanaka 2014,2014,1 gene,Tanaka-2014-A secreted Ustilago maydis effecto,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4304,PHI:3131,UniProt,I1RAE5,GenBank,ESU05658,,,PH-1,FgSCH9,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,kinase,,,TORC1 and cAMPPKA pathways,reduced virulence,,yes,,,,reduced; aberrant,,reduced,,no,H2O2; Congo red; NaCl; SDS,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,RP,25144230,PubMed,10.1371/journal.pone.0105811,PLoS One. 2014 Aug 21;9(8):e105811,jinrong@purdue.edu,"Mutants increased tolerance to elevated temperatures but became hypersensitive to oxidative, hyperosmotic, cell wall, and membrane stresses.",D Chen 2014,2014,2 genes,Chen-2014-The Sch9 Kinase Regulates Conidium S,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4305,PHI:3132,UniProt,L7JE74,GenBank,ELQ66169,,,P131,Mosch9,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,kinase,,,TORC1 and cAMPPKA pathways,reduced virulence,,yes,,,,reduced; aberrant,,reduced,,no,H2O2; Congo red; NaCl; SDS,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,RP,25144230,PubMed,10.1371/journal.pone.0105811,PLoS One. 2014 Aug 21;9(8):e105811,jinrong@purdue.edu,"Mutants increased tolerance to elevated temperatures but became hypersensitive to oxidative, hyperosmotic, cell wall, and membrane stresses.",D Chen 2014,2014,2 genes,Chen-2014-The Sch9 Kinase Regulates Conidium S,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4306,PHI:3131,UniProt,I1RAE5,GenBank,ESU05658,,,PH-1,FgSCH9,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,corn silk,kinase,,,TORC1 and cAMPPKA pathways,reduced virulence,,yes,,,,reduced; aberrant,,reduced,,no,H2O2; Congo red; NaCl; SDS,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,RP,25144230,PubMed,10.1371/journal.pone.0105811,PLoS One. 2014 Aug 21;9(8):e105811,jinrong@purdue.edu,"Mutants increased tolerance to elevated temperatures but became hypersensitive to oxidative, hyperosmotic, cell wall, and membrane stresses.",D Chen 2014,2014,2 genes,Chen-2014-The Sch9 Kinase Regulates Conidium S,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4307,PHI:3132,UniProt,V9GNU9,GenBank,GAE11165,,,NBRC 105692,arcA,,,,,,,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,Peyer's gland; mesenteric lymph node; liver; spleen,part of the pyruvate-tricarboxylic acid cycle node,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25164818,PubMed,10.1074/jbc.M114.581348,J Biol Chem. 2014 Aug 27. pii: jbc.M114.581348.,christoph.wittmann@uni-saarland.de,,R Bücker 2014,2014,4 genes,Bucker-2014-The Pyruvate - Tricarboxylic Acid,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4308,PHI:3133,UniProt,Q665I9,GenBank,CAH22766,,,IP 32953,ptsN,,,,,,,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,Peyer's gland; mesenteric lymph node; liver; spleen,part of the pyruvate-tricarboxylic acid cycle node,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25164818,PubMed,10.1074/jbc.M114.581348,J Biol Chem. 2014 Aug 27. pii: jbc.M114.581348.,christoph.wittmann@uni-saarland.de,,R Bücker 2014,2014,4 genes,Bucker-2014-The Pyruvate - Tricarboxylic Acid,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4309,PHI:3134,UniProt,Q66A26,GenBank,CAH21544,,,IP 32953,pykF,,,,,,,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,Peyer's gland; mesenteric lymph node; liver; spleen,part of the pyruvate-tricarboxylic acid cycle node,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25164818,PubMed,10.1074/jbc.M114.581348,J Biol Chem. 2014 Aug 27. pii: jbc.M114.581348.,christoph.wittmann@uni-saarland.de,,R Bücker 2014,2014,4 genes,Bucker-2014-The Pyruvate - Tricarboxylic Acid,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4310,PHI:3135,UniProt,Q66EI1,GenBank,CAH19952,,,IP 32953,pdhR,,,,,,,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,Peyer's gland; mesenteric lymph node; liver; spleen,part of the pyruvate-tricarboxylic acid cycle node,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25164818,PubMed,10.1074/jbc.M114.581348,J Biol Chem. 2014 Aug 27. pii: jbc.M114.581348.,christoph.wittmann@uni-saarland.de,,R Bücker 2014,2014,4 genes,Bucker-2014-The Pyruvate - Tricarboxylic Acid,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4311,PHI:3136,UniProt,B6V9Y4,GenBank,ACJ09357,,,,PsHSF1,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,stem,required for oxidative stress tolerance and detoxifying the plant oxidative burst,,,,reduced virulence,,no,no,yes,,wild type,wild type,wild type,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,RP,25156425,PubMed,10.1111/1462-2920.12609,Environ Microbiol. 2014 Aug 26,wangyc@njau.edu.cn,Growth reduced upon H202 exposure and higher temperatures.,Y Sheng 2014,2014,1 gene,Sheng-2014-The heat shock transcription factor,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4312,PHI:3137,UniProt,P50601,GenBank,AE004530_14,,,PAO1,TolB,,DtolB araCPBADtolB (PAO1araCPBADtolB deleted of the endogenous copy of tolB),,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"periplasmic component of the Tol-Pal system, a multi-protein complex present in almost all gram-negative bacteria which connects the cytoplasmic (or inner) membrane with the outer membrane.",,,,reduced virulence,,,,,,,,,,no,SDS; colistin; polymyxin B,SDS: CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309,,,,,gene mutation,,,RP,25093328,PubMed,10.1371/journal.pone.0103784,PLoS One. 2014 Aug 5;9(8):e103784,francesco.imperi@uniroma1.it,,A L Sciuto 2014,2014,1 gene,Lo Sciuto-2014-The Periplasmic Protein TolB as,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4313,PHI:3138,UniProt,I1REF2,GenBank,ESU07428,,,PH-1,ELP3,,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,"member of the GNAT family, is the catalytic subunit of the elongator complex.",,,,reduced virulence,,,,yes,,wild type; aberrant,reduced,reduced,wild type,no,NaCl; KCl; D-sorbitol; SDS; Congo red; fludioxonil; iprodione; benomyl; H2O2;,"KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; SDS: CHEBI:8984; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; benomyl: CHEBI:3015, CAS:17804-35-2; H2O2: CHEBI:16240; C,  Congo red: CHEBI:34653; NaCl: CHEBI:26710",,,,,gene deletion: full; gene complementation,,,RP,25083910,PubMed,10.1094/MPMI-05-14-0145-R,Mol Plant Microbe Interact. 2014 Aug 1,damnkool@snu.ac.k,Deletion mutants were more senstive to oxidative stress as compared to the wild type and complemented strains,Y LEE 2014,2014,1 gene,Lee-2014-ELP3 is Involved in Sexual and Asexua,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4314,PHI:3139,UniProt,J7I5J0,GenBank,AFQ34195,,,ATCC 9545,PlCBP49,,,,,,,1464,Paenibacillus larvae,147375,subsp. larvae strain ATCC 9545,American foulbrood,bees,7460,Apis mellifera (related: honey bee),,,,larva,"A modular, chitin-degrading protein, this enzyme is crucial for the degradation of the larval peritrophic matrix during infection.",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: downregulation,,,RP,25080221,PubMed,10.1371/journal.ppat.1004284,PLoS Pathog. 2014 Jul 31;10(7):e1004284,elke.genersch@rz.hu-berlin.de,The gene cbp49 coding for the protein PlCBP49 was disrupted to abolish the expression of PlCBP49.,E Garcia-Gonzalez 2014,2014,1 gene,Garcia-Gonzalez-2014-Paenibacillus larvae Chit,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4315,PHI:3140,UniProt,Q4R0Z0,GenBank,AAY78938,,,I9841/1,ArcD,,pGEM-arcD PvuII released erythromycin resistance cassette derived from vectorpICerm was used to disrupt ArcD,,,,,1307,Streptococcus suis,1214186,10,streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),,,,HEp-2 cell,arginine-ornithine antiporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25161959,PubMed,10.3389/fcimb.2014.00107,Front Cell Infect Microbiol. 2014 Aug 12;4:107,peter.valentin@tiho-hannover.de,"The mutant strain showed a markedly reduced growth in chemically defined media supplemented with arginine when compared to the WT strain, suggesting that ArcD promotes arginine uptake.",M Fulde 2014,2014,1 gene,Fulde-2014-The arginine-ornithine antiporter A,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4316,PHI:3141,UniProt,Q48245,GenBank,AAA17657,,,ATCC 49503,VacA,,60190deltavacA,,,,,210,Helicobacter pylori,563041,G27,gastric infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,virulence determinants,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25170542,PubMed,10.1186/s12866-014-0228-0,BMC Microbiol. 2014 Aug 27;14(1):228,vricci@unipv.it; rafzarri@unina.it,"H. pylori mutant strains defective in either VacA, or CagA, or CagE, orcagPAI, or urease, but not GGT-defective mutants, were less virulent than the respective parental strain.",M Giannouli 2014,2014,6 genes,Giannouli-2014-Use of larvae of the wax moth G,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4317,PHI:3142,UniProt,Q9JP55,GenBank,AAF43620,,,PeruGJ6,CagA,,G27deltacagA,,,,,210,Helicobacter pylori,563041,G27,gastric infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,virulence determinants,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25170542,PubMed,10.1186/s12866-014-0228-0,BMC Microbiol. 2014 Aug 27;14(1):228,vricci@unipv.it; rafzarri@unina.it,"H. pylori mutant strains defective in either VacA, or CagA, or CagE, orcagPAI, or urease, but not GGT-defective mutants, were less virulent than the respective parental strain.",M Giannouli 2014,2014,6 genes,Giannouli-2014-Use of larvae of the wax moth G,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4318,PHI:3143,UniProt,Q48252,GenBank,AAB63389,,,84-183,CagE,,G27deltacagE,,,,,210,Helicobacter pylori,563041,G27,gastric infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,virulence determinants,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25170542,PubMed,10.1186/s12866-014-0228-0,BMC Microbiol. 2014 Aug 27;14(1):228,vricci@unipv.it; rafzarri@unina.it,"H. pylori mutant strains defective in either VacA, or CagA, or CagE, orcagPAI, or urease, but not GGT-defective mutants, were less virulent than the respective parental strain.",M Giannouli 2014,2014,6 genes,Giannouli-2014-Use of larvae of the wax moth G,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4319,PHI:3144,UniProt,E2CYQ1,GenBank,ADK26520,,,I-34B,cagPAI,,G27deltacagPAI,,,,,210,Helicobacter pylori,563041,G27,gastric infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,virulence determinants,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25170542,PubMed,10.1186/s12866-014-0228-0,BMC Microbiol. 2014 Aug 27;14(1):228,vricci@unipv.it; rafzarri@unina.it,"H. pylori mutant strains defective in either VacA, or CagA, or CagE, orcagPAI, or urease, but not GGT-defective mutants, were less virulent than the respective parental strain.",M Giannouli 2014,2014,6 genes,Giannouli-2014-Use of larvae of the wax moth G,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4320,PHI:3145,UniProt,P69996,GenBank,AAA25021,,,,urease,,60190 Urease-negative,,,,,210,Helicobacter pylori,563041,G27,gastric infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,virulence determinants,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25170542,PubMed,10.1186/s12866-014-0228-0,BMC Microbiol. 2014 Aug 27;14(1):228,vricci@unipv.it; rafzarri@unina.it,"H. pylori mutant strains defective in either VacA, or CagA, or CagE, orcagPAI, or urease, but not GGT-defective mutants, were less virulent than the respective parental strain.",M Giannouli 2014,2014,6 genes,Giannouli-2014-Use of larvae of the wax moth G,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4321,PHI:3146,UniProt,O25743,GenBank,AAD08162,,,26695,GGT,,M5ggt::aph,,,,,210,Helicobacter pylori,563041,G27,gastric infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,virulence determinants,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25170542,PubMed,10.1186/s12866-014-0228-0,BMC Microbiol. 2014 Aug 27;14(1):228,vricci@unipv.it; rafzarri@unina.it,"H. pylori mutant strains defective in either VacA, or CagA, or CagE, orcagPAI, or urease, but not GGT-defective mutants, were less virulent than the respective parental strain.",M Giannouli 2014,2014,6 genes,Giannouli-2014-Use of larvae of the wax moth G,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4322,PHI:3147,UniProt,B8F4X8,GenBank,ACL32380,,,SH0165,rfaE,,,,,,,738,Glaesserella parasuis,,SC096,Glasser's disease,even-toed ungulates,9823,Sus scrofa (related: pig),PK-15 cell line,,,umbilical vein endothelial cell,part of cluster invloved in lipooligosaccharide synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25078003,PubMed,10.1016/j.micpath.2014.07.006,Microb Pathog. 2014 Sep;74:33-7,yhua900@163.com,"In adhesion and invasion assays, theDrfaEmutant strain had 10-fold less efficient adherence and 12-fold reductions in invasion of the porcine umbilicus vein endothelial cells (PUVEC) and porcine kidney epithelial cells (PK-15), respectively (p <0.001). Pathogen formerly called Haemophilus parasuis",B Zhang 2014,2014,1 gene,Zhang-2014-Deletion of the rfaE gene in Haemop,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4323,PHI:3148,UniProt,Q8DRE1,GenBank,AAK98981,,,R6,spr0177,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,,,,Lethal pathogen phenotype,,,,essential gene,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4324,PHI:3149,UniProt,Q8DQV4,GenBank,AAK99283,,,R6,spr0479,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,,,,Lethal pathogen phenotype,,,,essential gene,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4325,PHI:3150,UniProt,Q8CYR5,GenBank,AAK99839,,,R6,spr1035,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,,,,Lethal pathogen phenotype,,,,essential gene,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4326,PHI:3151,UniProt,Q8DP67,GenBank,AAL00131,,,R6,spr1327,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,,,,Lethal pathogen phenotype,,,,essential gene,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4327,PHI:3152,UniProt,P06653,GenBank,AAA26917,,,,lytA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,pathogenitcity related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4328,PHI:3153,UniProt,P59206,GenBank,CAA09078,,,R6,lytB,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,pathogenitcity related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4329,PHI:3154,UniProt,P67331,GenBank,AAK98888,,,R6,spr0084,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,pathogenitcity related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4330,PHI:3155,UniProt,Q8CZ89,GenBank,AAK98979,,,R6,spr0175,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,pathogenitcity related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4331,PHI:3156,UniProt,Q8DPY9,GenBank,AAK99734,,,R6,spr0930,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,pathogenitcity related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4332,PHI:3157,UniProt,Q8DPV2,GenBank,AAK99795,,,R6,spr0991,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,pathogenitcity related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4333,PHI:3158,UniProt,Q8DMX7,GenBank,AAL00830,,,R6,spr2028,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,pathogenitcity related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4334,PHI:3159,UniProt,P67267,GenBank,AAK99814,,,R6,spr1010,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,pathogenitcity related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4335,PHI:3160,UniProt,Q8DPA4,GenBank,AAL00072,,,R6,spr1268,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25096389,PubMed,10.1186/1471-2164-15-652,BMC Genomics. 2014 Aug 5;15:652,mgaliano@isciii.es,,A J Martín-Galiano 2014,2014,13 genes,Martin-Galiano-2014-Inspecting the potential p,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4336,PHI:3161,UniProt,G4MKP6,GenBank,EHA56736,,,70-15,Mohik5,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,histidine kinase,,,,loss of pathogenicity,,,,,,reduced; aberrant,,reduced,,no,NaCl; NaNO2; sorbitol; CoCl2; CuSO4; H2O2,H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; NaNo2: CHEBI:78870; CoCl2: CHEBI:35696; CuSO4: CHEBI:23414,,,,,gene deletion: full,,,RP,25103193,PubMed,10.1002/mbo3.197,Microbiologyopen. 2014 Aug 8,jacob@ibwf.de; thines@ibwf.de,Mutants more sentisitve to stress,S Jacob 2014,2014,3 genes,Jacob-2014-Histidine kinases mediate different,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4337,PHI:3162,UniProt,G4MXJ1,GenBank,EHA54322,,,70-15,Mohik8,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,histidine kinase,,,,loss of pathogenicity,,,,,,reduced; aberrant,,reduced,,no,NaCl; NaNO2; sorbitol; CoCl2; CuSO4; H2O2,H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; NaNo2: CHEBI:78870; CoCl2: CHEBI:35696; CuSO4: CHEBI:23414,,,,,gene deletion: full,,,RP,25103193,PubMed,10.1002/mbo3.197,Microbiologyopen. 2014 Aug 8,jacob@ibwf.de; thines@ibwf.de,Mutants more sentisitve to stress,S Jacob 2014,2014,3 genes,Jacob-2014-Histidine kinases mediate different,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4338,PHI:3163,UniProt,G4MV04,GenBank,EHA55738,,,70-15,Mosln1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,histidine kinase,,,,reduced virulence,,,,,few lesions,reduced; aberrant,,reduced,,no,NaCl; NaNO2; sorbitol; CoCl2; CuSO4; H2O2,H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; NaNo2: CHEBI:78870; CoCl2: CHEBI:35696; CuSO4: CHEBI:23414,,,,,gene deletion: full,,,RP,25103193,PubMed,10.1002/mbo3.197,Microbiologyopen. 2014 Aug 8,jacob@ibwf.de; thines@ibwf.de,Mutants more sentisitve to stress,S Jacob 2014,2014,3 genes,Jacob-2014-Histidine kinases mediate different,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4339,PHI:3164,UniProt,R9UM22,GenBank,AGN70889,,,NBAII Tvs5,Sm1,,,,,,,29875,Trichoderma virens,413071,Gv29-8,non-pathogenic: biocontrol,monocots,4577,Zea mays (related: maize),cv. B73,,,root,hydrophobinlike elicitor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,resistance,the presence of the gene sm1 from trichoderma virens (root nodules) confers resistance to maize against colletotrichum graminicola infections.,gene deletion: full,,,RP,17885089,PubMed,10.1104/pp.107.103689,Plant Physiol. 2007 Nov;145(3):875-89. Epub 2007 Sep 20,c-kenerley@tamu.edu,,S Djonovic 2007,2007,1 gene,Djonovic-2007-A proteinaceous elicitor Sm1 fro,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4340,PHI:3164,UniProt,R9UM22,GenBank,AGN70889,,,NBAII Tvs5,Sm1,,,,,,,29875,Trichoderma virens,413071,Gv29-8,non-pathogenic: biocontrol,monocots,4577,Zea mays (related: maize),cv. B73,,,root,hydrophobinlike elicitor,,,,reduced virulence,,,,,,,,,,no,,,,,resistance,the presence of the gene sm1 from trichoderma virens (root nodules) confers resistance to maize against colletotrichum graminicola infections.,altered gene expression / gene regulation: overexpression,,,RP,17885089,PubMed,10.1104/pp.107.103689,Plant Physiol. 2007 Nov;145(3):875-89. Epub 2007 Sep 20,c-kenerley@tamu.edu,,S Djonovic 2007,2007,1 gene,Djonovic-2007-A proteinaceous elicitor Sm1 fro,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4341,PHI:3164,UniProt,R9UM22,GenBank,AGN70889,,,NBAII Tvs5,Sm1,,,,,,,29875,Trichoderma virens,413071,Gv29-8,non-pathogenic: biocontrol,monocots,4530,Oryza sativa (related: rice),cv. M-202,,,root,hydrophobinlike elicitor,,,,reduced virulence,,,,,,,,,,no,,,,,resistance,the presence of the gene sm1 from trichoderma virens (root nodules) confers resistance against colletotrichum sp. infections.,functional test in host: transient expression,,,RP,17885089,PubMed,10.1104/pp.107.103689,Plant Physiol. 2007 Nov;145(3):875-89. Epub 2007 Sep 20,c-kenerley@tamu.edu,,S Djonovic 2007,2007,1 gene,Djonovic-2007-A proteinaceous elicitor Sm1 fro,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4342,PHI:3164,UniProt,R9UM22,GenBank,AGN70889,,,NBAII Tvs5,Sm1,,,,,,,29875,Trichoderma virens,413071,Gv29-8,non-pathogenic: biocontrol,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Paymaster 2326 BG/RR; cv. Deltapine 50,,,root,hydrophobinlike elicitor,,,,reduced virulence,,,,,,,,,,no,,,,,resistance,the presence of the gene sm1 from trichoderma virens (root nodules) confers resistance against colletotrichum sp. infections.,functional test in host: transient expression,,,RP,17885089,PubMed,10.1104/pp.107.103689,Plant Physiol. 2007 Nov;145(3):875-89. Epub 2007 Sep 20,c-kenerley@tamu.edu,,S Djonovic 2007,2007,1 gene,Djonovic-2007-A proteinaceous elicitor Sm1 fro,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4343,PHI:3165,UniProt,W0H866,GenBank,AHF65896,,,JBC1,hopA1,,,,,,,36746,Pseudomonas cichorii,1441629,JBC1,leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,effector (plant avirulence determinant),,,anthocyanin biosynthesis,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25127676,PubMed,10.1016/j.resmic.2014.08.001,Res Microbiol. 2014 Aug 12. pii: S0923-2508(14)00120-X,yonghoonlee@jbnu.ac.kr,,N B Hung 2014,2014,1 gene,Hung-2014-An effector gene hopA1 influences on,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4344,PHI:3165,UniProt,W0H866,GenBank,AHF65896,,,JBC1,hopA1,,,,,,,36746,Pseudomonas cichorii,1441629,JBC1,leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean),eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,effector (plant avirulence determinant),,,anthocyanin biosynthesis,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25127676,PubMed,10.1016/j.resmic.2014.08.001,Res Microbiol. 2014 Aug 12. pii: S0923-2508(14)00120-X,yonghoonlee@jbnu.ac.kr,,N B Hung 2014,2014,1 gene,Hung-2014-An effector gene hopA1 influences on,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4345,PHI:3165,UniProt,W0H866,GenBank,AHF65896,,,JBC1,hopA1,,,,,,,36746,Pseudomonas cichorii,1441629,JBC1,leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean),eudicots,3847,Glycine max (related: soybean),,,,leaf,effector (plant avirulence determinant),,,anthocyanin biosynthesis,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25127676,PubMed,10.1016/j.resmic.2014.08.001,Res Microbiol. 2014 Aug 12. pii: S0923-2508(14)00120-X,yonghoonlee@jbnu.ac.kr,,N B Hung 2014,2014,1 gene,Hung-2014-An effector gene hopA1 influences on,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4346,PHI:3165,UniProt,W0H866,GenBank,AHF65896,,,JBC1,hopA1,,,,,,,36746,Pseudomonas cichorii,1441629,JBC1,leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean),eudicots,4073,Capsicum frutescens (related: hot pepper),,,,leaf,effector (plant avirulence determinant),,,anthocyanin biosynthesis,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25127676,PubMed,10.1016/j.resmic.2014.08.001,Res Microbiol. 2014 Aug 12. pii: S0923-2508(14)00120-X,yonghoonlee@jbnu.ac.kr,,N B Hung 2014,2014,1 gene,Hung-2014-An effector gene hopA1 influences on,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4347,PHI:3165,UniProt,W0H866,GenBank,AHF65896,,,JBC1,hopA1,,,,,,,36746,Pseudomonas cichorii,1441629,JBC1,leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean),eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,effector (plant avirulence determinant),,,anthocyanin biosynthesis,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25127676,PubMed,10.1016/j.resmic.2014.08.001,Res Microbiol. 2014 Aug 12. pii: S0923-2508(14)00120-X,yonghoonlee@jbnu.ac.kr,,N B Hung 2014,2014,1 gene,Hung-2014-An effector gene hopA1 influences on,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4348,PHI:3165,UniProt,W0H866,GenBank,AHF65896,,,JBC1,hopA1,,,,,,,36746,Pseudomonas cichorii,1441629,JBC1,leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean),eudicots,3656,Cucumis melo (related: muskmelon),,,,leaf,effector (plant avirulence determinant),,,anthocyanin biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25127676,PubMed,10.1016/j.resmic.2014.08.001,Res Microbiol. 2014 Aug 12. pii: S0923-2508(14)00120-X,yonghoonlee@jbnu.ac.kr,,N B Hung 2014,2014,1 gene,Hung-2014-An effector gene hopA1 influences on,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4349,PHI:3165,UniProt,W0H866,GenBank,AHF65896,,,JBC1,hopA1,,,,,,,36746,Pseudomonas cichorii,1441629,JBC1,leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean),eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector (plant avirulence determinant),,,anthocyanin biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25127676,PubMed,10.1016/j.resmic.2014.08.001,Res Microbiol. 2014 Aug 12. pii: S0923-2508(14)00120-X,yonghoonlee@jbnu.ac.kr,,N B Hung 2014,2014,1 gene,Hung-2014-An effector gene hopA1 influences on,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4350,PHI:3166,UniProt,Q9I690,GenBank,AE004479_7,,,PAO1,PA0423,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,A-549 cell,factor responsible for cytotoxicity in lung epithelial cells,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25152458,PubMed,10.1016/j.micpath.2014.08.002,Microb Pathog. 2014 Oct;75C:35-40,watanabn@sapmed.ac.jp,,M Shinagawa 2014,2014,1 gene,Shinagawa-2014-Identification of a bacteriolys,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4351,PHI:3166,UniProt,Q9I690,GenBank,AE004479_7,,,PAO1,PA0423,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,A-549 cell,factor responsible for cytotoxicity in lung epithelial cells,,,,reduced virulence,,,,,,,,,,no,,,,,,,biochemical analysis,recombinant PA0122 and PA0423 were transduced into A549 cells using bioporter protein delivery reagents,,RP,25152458,PubMed,10.1016/j.micpath.2014.08.002,Microb Pathog. 2014 Oct;75C:35-40,watanabn@sapmed.ac.jp,,M Shinagawa 2014,2014,1 gene,Shinagawa-2014-Identification of a bacteriolys,Batch041,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4352,PHI:3167,UniProt,P81702,GenBank,AGQ22233,,,CBS115175,Cerato-platanin,,,,,,,5158,Ceratocystis fimbriata,,f. sp. platani strain AF 100,canker stain,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,phytotoxic protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,necrosis,functional test in host: direct injection,,,RP,10455173,PubMed,10.1074/jbc.274.35.24959,J Biol Chem. 1999 Aug 27;274(35):24959-64,scala@ipaf.fi.cnr.it,,L Pazzagli 1999,1999,1 gene,"Pazzagli-1999-Purification, characterization",Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4353,PHI:3168,UniProt,J9N5P9,Broad,FOXG_10510,,,4287,SGE1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker ss590,,,leaf,transcriptional regulators involved in morphological switching in dimorphic fungal pathogens.,,,,reduced virulence,,no,no,yes,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,19851506,PubMed,10.1371/journal.ppat.1000637,PLoS Pathog. 2009 Oct;5(10):e1000637,c.b.michielse@uni-muenster.de,Fusarium oxysporum f. sp. lycopersici exerts biocontrolactivity on flax when added in a 100-fold excess relative to a F.oxysporum strain pathogenic towards flax.,C B Michielse 2009,2009,1 gene,Michielse-2009-The Nuclear Protein Sge1 of Fus,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4354,PHI:3169,UniProt,Q8YC53,GenBank,LOVHK_BRUME,,,16M,BM-LOV-HK,,,,,,,29459,Brucella melitensis,224914,16M,brucellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,light sensing histidine kinase,,,,reduced virulence,,,,,2 logs fewer CFUs,,,,,no,,,,,,,gene deletion: full,,,RP,25132657,PubMed,10.1111/2049-632X.12209,Pathog Dis. 2014 Jul 29,splitter@svm.vetmed.wisc.edu,,C R Gourley 2014,2014,1 gene,Gourley-2014-Decreased in vivo virulence and a,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4355,PHI:3169,UniProt,Q8YC53,GenBank,LOVHK_BRUME,,,16M,BM-LOV-HK,,,,,,,29459,Brucella melitensis,224914,16M,brucellosis,rodents,10090,Mus musculus (related: house mouse),IRF-1<-/->,,,spleen,light sensing histidine kinase,,,,reduced virulence,,,,,significantly increased survival,,,,,no,,,,,,,gene deletion: full,,,RP,25132657,PubMed,10.1111/2049-632X.12209,Pathog Dis. 2014 Jul 29,splitter@svm.vetmed.wisc.edu,,C R Gourley 2014,2014,1 gene,Gourley-2014-Decreased in vivo virulence and a,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4356,PHI:3520,UniProt,Q9I322,GenBank,AE004597_1,,,PAO1,exsE,,,,,,PHI:3521,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,gastrointestinal tract,type III secretion (T3S) system,,,,reduced virulence,,,,,,,,,,no,,,,,,the mutants reduced in virulence were chosen by C. elegans for feeding over the mutants with wild type pathogenticity.,functional test in host: transient expression,,,RP,25165631,PubMed,10.7717/peerj.521,PeerJ. 2014 Aug 12;2:e521,slewenza@ucalgary.ca,,S Lewenza 2014,2014,3 genes,Lewenza-2014-Feeding behaviour of Caenorhabdit,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4357,PHI:3521,UniProt,B7VBG2,GenBank,CAW28339,,,LESB58,pscD,,,,,,PHI:3520,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,gastrointestinal tract,type III secretion (T3S) system,,,,reduced virulence,,,,,,,,,,no,,,,,,the mutants reduced in virulence were chosen by C. elegans for feeding over the mutants with wild type pathogenticity.,functional test in host: transient expression,,,RP,25165631,PubMed,10.7717/peerj.521,PeerJ. 2014 Aug 12;2:e521,slewenza@ucalgary.ca,,S Lewenza 2014,2014,3 genes,Lewenza-2014-Feeding behaviour of Caenorhabdit,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4358,PHI:3522,UniProt,P20582,GenBank,AAG04388,,,PAO1,pqsD,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,gastrointestinal tract,"required for the synthesis of the Pseudomonas quinolone signal, a quorum sensing signal molecule that contributes to slow killing and the red death phenotype in C. elegans.",,,PQS biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,the mutants reduced in virulence were chosen by C. elegans for feeding over the mutants with wild type pathogenticity.,functional test in host: transient expression,,,RP,25165631,PubMed,10.7717/peerj.521,PeerJ. 2014 Aug 12;2:e521,slewenza@ucalgary.ca,,S Lewenza 2014,2014,3 genes,Lewenza-2014-Feeding behaviour of Caenorhabdit,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4359,PHI:3524,UniProt,B4E5A2,GenBank,CAR50527,,,J2315,paaA,,,,,,PHI:3525; PHI:3170; PHI:3171; PHI:3172,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),DH26,,,gastrointestinal tract,phenylacetic acid catabolism,,,phenylacetic acid degradation pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25155974,PubMed,10.1111/mmi.12771,Mol Microbiol. 2014 Aug 26,Silvia.Cardona@umanitoba.ca,Deletion of gene cluster paaABCDE causes PAA-defective growth.,T Pribytkova 2014,2014,5 genes,Pribytkova-2014-The attenuated virulence of a,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4360,PHI:3525,UniProt,B4E5A0,GenBank,CAR50525,,,J2315,paaC,,,,,,PHI:3524; PHI:3170; PHI:3171; PHI:3172,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),DH26,,,gastrointestinal tract,phenylacetic acid catabolism,,,phenylacetic acid degradation pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25155974,PubMed,10.1111/mmi.12771,Mol Microbiol. 2014 Aug 26,Silvia.Cardona@umanitoba.ca,Deletion of gene cluster paaABCDE causes PAA-defective growth.,T Pribytkova 2014,2014,5 genes,Pribytkova-2014-The attenuated virulence of a,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4361,PHI:3170,UniProt,B4E5A1,GenBank,CAR50526,,,J2315,paaB,,,,,,PHI:3524; PHI:3525; PHI:3171; PHI:3172,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),DH26,,,gastrointestinal tract,phenylacetic acid catabolism,,,phenylacetic acid degradation pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25155974,PubMed,10.1111/mmi.12771,Mol Microbiol. 2014 Aug 26,Silvia.Cardona@umanitoba.ca,Deletion of gene cluster paaABCDE causes PAA-defective growth.,T Pribytkova 2014,2014,5 genes,Pribytkova-2014-The attenuated virulence of a,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4362,PHI:3171,UniProt,B4E599,GenBank,CAR50524,,,J2315,paaD,,,,,,PHI:3524; PHI:3525; PHI:3170; PHI:3172,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),DH26,,,gastrointestinal tract,phenylacetic acid catabolism,,,phenylacetic acid degradation pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25155974,PubMed,10.1111/mmi.12771,Mol Microbiol. 2014 Aug 26,Silvia.Cardona@umanitoba.ca,Deletion of gene cluster paaABCDE causes PAA-defective growth.,T Pribytkova 2014,2014,5 genes,Pribytkova-2014-The attenuated virulence of a,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4363,PHI:3172,UniProt,B4E598,GenBank,CAR50523,,,J2315,paaE,,,,,,PHI:3524; PHI:3525; PHI:3170; PHI:3171,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),DH26,,,gastrointestinal tract,phenylacetic acid catabolism,,,phenylacetic acid degradation pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25155974,PubMed,10.1111/mmi.12771,Mol Microbiol. 2014 Aug 26,Silvia.Cardona@umanitoba.ca,Deletion of gene cluster paaABCDE causes PAA-defective growth.,T Pribytkova 2014,2014,5 genes,Pribytkova-2014-The attenuated virulence of a,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4364,PHI:3173,UniProt,G4NEB4,GenBank,EHA48597,,,70-15,Mosnf1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,central role in response to nutrient stress,,,SNF1/AMPK pathway,loss of pathogenicity,,yes,yes,,,reduced,,wild type; aberrant,reduced,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full; gene complementation,,,RP,25090011,PubMed,10.1371/journal.pone.0103124,PLoS One. 2014 Aug 4;9(8):e103124,fuchenglin@zju.edu.cn,Exogenous glucose could partially restore the appressorial function and virulence.,X Zeng 2014,2014,5 genes,Zeng-2014-Crosstalk between SNF1 Pathway and t,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4365,PHI:3174,UniProt,G4MNE3,GenBank,EHA57057,,,70-15,MoSip2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,central role in response to nutrient stress,,,SNF1/AMPK pathway,loss of pathogenicity,,yes,yes,,,reduced,,wild type; aberrant,reduced,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full; gene complementation,,,RP,25090011,PubMed,10.1371/journal.pone.0103124,PLoS One. 2014 Aug 4;9(8):e103124,fuchenglin@zju.edu.cn,Exogenous glucose could partially restore the appressorial function and virulence.,X Zeng 2014,2014,5 genes,Zeng-2014-Crosstalk between SNF1 Pathway and t,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4366,PHI:3175,UniProt,G4NGW8,GenBank,EHA47478,,,70-15,MoSnf4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,central role in response to nutrient stress,,,SNF1/AMPK pathway,loss of pathogenicity,,yes,yes,,,reduced,,wild type; aberrant,reduced,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full; gene complementation,,,RP,25090011,PubMed,10.1371/journal.pone.0103124,PLoS One. 2014 Aug 4;9(8):e103124,fuchenglin@zju.edu.cn,Exogenous glucose could partially restore the appressorial function and virulence.,X Zeng 2014,2014,5 genes,Zeng-2014-Crosstalk between SNF1 Pathway and t,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4367,PHI:3176,UniProt,G4MNZ0,GenBank,EHA57147,,,70-15,MoSak1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,putative Snf1-activating kinases,,,SNF1/AMPK pathway,reduced virulence,,yes,yes,,,reduced,,reduced,reduced,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full; gene complementation,,,RP,25090011,PubMed,10.1371/journal.pone.0103124,PLoS One. 2014 Aug 4;9(8):e103124,fuchenglin@zju.edu.cn,Exogenous glucose could partially restore the appressorial function and virulence.,X Zeng 2014,2014,5 genes,Zeng-2014-Crosstalk between SNF1 Pathway and t,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4368,PHI:3177,UniProt,G4N7H1,GenBank,EHA50828,,,70-15,MoTos3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,putative Snf1-activating kinases,,,SNF1/AMPK pathway,unaffected pathogenicity,,no,no,,,increased,,increased; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25090011,PubMed,10.1371/journal.pone.0103124,PLoS One. 2014 Aug 4;9(8):e103124,fuchenglin@zju.edu.cn,Exogenous glucose could partially restore the appressorial function and virulence.,X Zeng 2014,2014,5 genes,Zeng-2014-Crosstalk between SNF1 Pathway and t,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4369,PHI:3176,UniProt,G4MNZ0,GenBank,EHA57147,,,70-15,MoSak1,,,,,,PHI:3177,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,putative Snf1-activating kinases,,,SNF1/AMPK pathway,reduced virulence,,yes,yes,,,reduced,,reduced,reduced,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full; gene complementation,,,RP,25090011,PubMed,10.1371/journal.pone.0103124,PLoS One. 2014 Aug 4;9(8):e103124,fuchenglin@zju.edu.cn,Exogenous glucose could partially restore the appressorial function and virulence.,X Zeng 2014,2014,5 genes,Zeng-2014-Crosstalk between SNF1 Pathway and t,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4370,PHI:3177,UniProt,G4N7H1,GenBank,EHA50828,,,70-15,MoTos3,,,,,,PHI:3176,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,putative Snf1-activating kinases,,,SNF1/AMPK pathway,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full; gene complementation,,,RP,25090011,PubMed,10.1371/journal.pone.0103124,PLoS One. 2014 Aug 4;9(8):e103124,fuchenglin@zju.edu.cn,Exogenous glucose could partially restore the appressorial function and virulence.,X Zeng 2014,2014,5 genes,Zeng-2014-Crosstalk between SNF1 Pathway and t,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4371,PHI:3178,UniProt,A0A0E0SDV0,EMBL,FGRAMPH1_01T27499,,,PH-1,FgKin1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,kinases,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,reduced,no,SDS; H2O2; NaCl; calcofluor; Congo red,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene mutation,,,RP,25078365,PubMed,10.1111/nph.12953,New Phytol. 2014 Jul 31,jinrong@purdue.edu,Kin1 regulates the localizationof Tub1b-tubulins inFusarium graminearum.,Y Luo 2014,2014,2 genes,Luo-2014-FgKin1 kinase localizes to the septal,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4372,PHI:3179,UniProt,G4MY59,GenBank,EHA54390,,,70-15,MoKIN1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,,kinases,,,,reduced virulence,,no,no,,,reduced,,reduced,reduced,no,,,,,,,gene mutation,,,RP,25078365,PubMed,10.1111/nph.12953,New Phytol. 2014 Jul 31,jinrong@purdue.edu,Kin1 regulates the localizationof Tub1b-tubulins.,Y Luo 2014,2014,2 genes,Luo-2014-FgKin1 kinase localizes to the septal,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4373,PHI:3180,UniProt,J9NF60,BROAD,FOXG_13835,,,4287,Rho1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Vemar,,,root,Rho-type GTPases,,,,reduced virulence,,,,,,,,reduced,,no,sorbitol; calcofluor white,calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene mutation,,,RP,18248628,PubMed,10.1111/j.1462-5822.2008.01130.x,Cell Microbiol. 2008 Jun;10(6):1339-51,ge2dipia@uco.es,"F. oxysporum strains carrying either a Drho1loss-of-function mutation or a rho1G14V gain-offunction allele were viable, but displayed a severely restricted colony phenotype which was partiallyrelieved by the osmotic stabilizer sorbitol, indicating structural alterations in the cell wall. Consistent with this hypothesis, Drho1 strains showed increased resistance to cell wall-degrading enzymes and staining with Calcofluor white.",A L Martínez-Rocha 2008,2008,1 gene,Martinez-Rocha-2008-Rho1 has distinct function,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4374,PHI:3180,UniProt,J9NF60,BROAD,FOXG_13835,,,4287,Rho1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,fruit,Rho-type GTPases,,,,reduced virulence,,,,,,,,reduced,,no,sorbitol; calcofluor white,calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene mutation,,,RP,18248628,PubMed,10.1111/j.1462-5822.2008.01130.x,Cell Microbiol. 2008 Jun;10(6):1339-51,ge2dipia@uco.es,"F. oxysporum strains carrying either a Drho1loss-of-function mutation or a rho1G14V gain-offunction allele were viable, but displayed a severely restricted colony phenotype which was partiallyrelieved by the osmotic stabilizer sorbitol, indicating structural alterations in the cell wall. Consistent with this hypothesis, Drho1 strains showed increased resistance to cell wall-degrading enzymes and staining with Calcofluor white.",A L Martínez-Rocha 2008,2008,1 gene,Martinez-Rocha-2008-Rho1 has distinct function,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4375,PHI:3180,UniProt,J9NF60,BROAD,FOXG_13835,,,4287,Rho1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,rodents,10090,Mus musculus (related: house mouse),,,,,Rho-type GTPases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,18248628,PubMed,10.1111/j.1462-5822.2008.01130.x,Cell Microbiol. 2008 Jun;10(6):1339-51,ge2dipia@uco.es,"F. oxysporum strains carrying either a Drho1loss-of-function mutation or a rho1G14V gain-offunction allele were viable, but displayed a severely restricted colony phenotype which was partiallyrelieved by the osmotic stabilizer sorbitol, indicating structural alterations in the cell wall. Consistent with this hypothesis, Drho1 strains showed increased resistance to cell wall-degrading enzymes and staining with Calcofluor white.",A L Martínez-Rocha 2008,2008,1 gene,Martinez-Rocha-2008-Rho1 has distinct function,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4376,PHI:3181,UniProt,G0X877,GenBank,AEK86966,,,RK122,Um05294,,,,,,PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4377,PHI:3182,UniProt,G0X7N7,GenBank,AEK86783,,,RK208,Um10554,,,,,,PHI:3181; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4378,PHI:3183,UniProt,G0X860,GenBank,AEK86957,,,RK122,Um05295,,,,,,PHI:3181; PHI:3182; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4379,PHI:3184,UniProt,G0X7F2,GenBank,AEK86698,,,RK124,Um12302,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4380,PHI:3185,UniProt,G0X7P5,GenBank,AEK86791,,,RK123,Um10553,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4381,PHI:3186,UniProt,G0X854,GenBank,AEK86951,,,RK126,Um05299,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4382,PHI:3187,UniProt,G0X849,GenBank,AEK86941,,,RK124,Um05300,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4383,PHI:3188,UniProt,G3CK64,GenBank,AEN25695,,,RK126,Um05301,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4384,PHI:3189,UniProt,G3CK64,GenBank,AEN25695,,,RK126,Um05305,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4385,PHI:3190,UniProt,G0X809,GenBank,AEK86905,,,RK124,Um05306,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4386,PHI:3191,UniProt,G3CK59,GenBank,AEN25689,,,RK126,Um05309,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4387,PHI:3192,UniProt,G0X7Z5,GenBank,AEK86885,,,RK122,Um05310,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4388,PHI:3193,UniProt,G0X7Y1,GenBank,AEK86877,,,RK208,Um05311,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4389,PHI:3194,UniProt,G0X7X3,GenBank,AEK86867,,,RK122,Um05312,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4390,PHI:3195,UniProt,G0X7K3,GenBank,AEK86750,,,RK122,Um10557,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4391,PHI:3196,UniProt,G0X7U0,GenBank,AEK86831,,,RK122,Um05317,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4392,PHI:3197,UniProt,G0X7V8,GenBank,AEK86849,,,RK122,Um05314,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4393,PHI:3198,UniProt,G0X7S7,GenBank,AEK86822,,,RK122,Um05318,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4394,PHI:3199,UniProt,G0X7S0,GenBank,AEK86813,,,RK122,Um05319,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4395,PHI:3200,UniProt,G0X840,GenBank,AEK86931,,,RK122,Um05302,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4396,PHI:3201,UniProt,G0X828,GenBank,AEK8692,,,RK124,Um05303,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4397,PHI:3202,UniProt,G0X7M4,GenBank,AEK86768,,,RK217,Um10555,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4398,PHI:3203,UniProt,G0X7L8,GenBank,AEK86759,,,RK122,Um10556,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203; PHI:3204,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4399,PHI:3204,UniProt,G0X801,GenBank,AEK86894,,,RK122,Um05308,,,,,,PHI:3181; PHI:3182; PHI:3183; PHI:3184; PHI:3185; PHI:3186; PHI:3187; PHI:3188; PHI:3189; PHI:3190; PHI:3191; PHI:3192; PHI:3193; PHI:3194; PHI:3195; PHI:3196; PHI:3197; PHI:3198; PHI:3199; PHI:3200; PHI:3201; PHI:3202; PHI:3203,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,part of the largest effector gene cluster,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24992561,PubMed,10.1371/journal.ppat.1003866,PLoS Pathog. 2014 Jul 3;10(7):e1003866,kahmann@mpi-marburg.mpg.de,,T Brefort 2014,2014,24 genes,Brefort-2014-Characterization of the largest e,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4400,PHI:3205,UniProt,Q4WTR6,GenBank,EAL92010,,,Af293,Mid1,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,calcium homeostasis and signaling,,,calcium signalling,reduced virulence,,,,,,,,reduced,,no,paraquat; CaCl2; calcineurin; cyclosporine; EGTA; voriconazole; ketoconazole; itraconazole; caspofungin,"paraquat: CHEBI:34905; CaCl2: CHEBI:3312; calcineurin: CAS:90371-51-0; cyclosporine: CHEBI:4031; EGTA: CHEBI:30740; voriconazole: CHEBI:10023; ketoconazole: CHEBI:47519, CAS:65277-42-1; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180",,,,,gene deletion: full; gene complementation,,,RP,25083783,PubMed,10.1371/journal.pone.0103957,PLoS One. 2014 Aug 1;9(8):e103957,ggoldman@usp.br,"DcchA, DmidAandDcchA DmidAstrains demonstrated increased sensitivity to the oxidative stress inducer, paraquat. Growth defect in mutants was rescued by CaCl2.",P A de Castro 2014,2014,3 genes,de Castro-2014-The Involvement of the Mid1_Cch,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4401,PHI:3206,UniProt,B0XQN0,GenBank,EDP56344,,,A1163,Cch1,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,calcium homeostasis and signaling,,,calcium signalling,reduced virulence,,,,,,,,reduced,,no,paraquat; CaCl2; calcineurin; cyclosporine; EGTA; voriconazole; ketoconazole; itraconazole; caspofungin,"paraquat: CHEBI:34905; CaCl2: CHEBI:3312; calcineurin: CAS:90371-51-0; cyclosporine: CHEBI:4031; EGTA: CHEBI:30740; voriconazole: CHEBI:10023; ketoconazole: CHEBI:47519, CAS:65277-42-1; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180",,,,,gene deletion: full; gene complementation,,,RP,25083783,PubMed,10.1371/journal.pone.0103957,PLoS One. 2014 Aug 1;9(8):e103957,ggoldman@usp.br,"DcchA, DmidAandDcchA DmidAstrains demonstrated increased sensitivity to the oxidative stress inducer, paraquat. Growth defect in mutants was rescued by CaCl2.",P A de Castro 2014,2014,3 genes,de Castro-2014-The Involvement of the Mid1_Cch,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4402,PHI:3207,UniProt,A1CLC0,GenBank,EAW09944,,,NRRL 1,Yvc1,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,calcium homeostasis and signaling,,,calcium signalling,reduced virulence,,,,,,,,wild type,,no,paraquat; CaCl2; calcineurin; cyclosporine; EGTA; voriconazole; ketoconazole; itraconazole; caspofungin,"paraquat: CHEBI:34905; CaCl2: CHEBI:3312; calcineurin: CAS:90371-51-0; cyclosporine: CHEBI:4031; EGTA: CHEBI:30740; voriconazole: CHEBI:10023; ketoconazole: CHEBI:47519, CAS:65277-42-1; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180",,,,,gene deletion: full; gene complementation,,,RP,25083783,PubMed,10.1371/journal.pone.0103957,PLoS One. 2014 Aug 1;9(8):e103957,ggoldman@usp.br,"DcchA, DmidAandDcchA DmidAstrains demonstrated increased sensitivity to the oxidative stress inducer, paraquat. Growth defect in mutants was rescued by CaCl2.",P A de Castro 2014,2014,3 genes,de Castro-2014-The Involvement of the Mid1_Cch,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4403,PHI:3205,UniProt,Q4WTR6,GenBank,EAL92010,,,Af293,Mid1,,,,,,PHI:3206,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,calcium homeostasis and signaling,,,calcium signalling,reduced virulence,,,,,,,,reduced,,no,paraquat; CaCl2; calcineurin; cyclosporine; EGTA; voriconazole; ketoconazole; itraconazole; caspofungin,"paraquat: CHEBI:34905; CaCl2: CHEBI:3312; calcineurin: CAS:90371-51-0; cyclosporine: CHEBI:4031; EGTA: CHEBI:30740; voriconazole: CHEBI:10023; ketoconazole: CHEBI:47519, CAS:65277-42-1; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180",,,,,gene deletion: full; gene complementation,,,RP,25083783,PubMed,10.1371/journal.pone.0103957,PLoS One. 2014 Aug 1;9(8):e103957,ggoldman@usp.br,"DcchA, DmidAandDcchA DmidAstrains demonstrated increased sensitivity to the oxidative stress inducer, paraquat. Growth defect in mutants was rescued by CaCl2.",P A de Castro 2014,2014,3 genes,de Castro-2014-The Involvement of the Mid1_Cch,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4404,PHI:3206,UniProt,B0XQN0,GenBank,EDP56344,,,A1163,Cch1,,,,,,PHI:3205,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,calcium homeostasis and signaling,,,calcium signalling,reduced virulence,,,,,,,,reduced,,no,paraquat; CaCl2; calcineurin; cyclosporine; EGTA; voriconazole; ketoconazole; itraconazole; caspofungin,"paraquat: CHEBI:34905; CaCl2: CHEBI:3312; calcineurin: CAS:90371-51-0; cyclosporine: CHEBI:4031; EGTA: CHEBI:30740; voriconazole: CHEBI:10023; ketoconazole: CHEBI:47519, CAS:65277-42-1; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180",,,,,gene deletion: full; gene complementation,,,RP,25083783,PubMed,10.1371/journal.pone.0103957,PLoS One. 2014 Aug 1;9(8):e103957,ggoldman@usp.br,"DcchA, DmidAandDcchA DmidAstrains demonstrated increased sensitivity to the oxidative stress inducer, paraquat. Growth defect in mutants was rescued by CaCl2.",P A de Castro 2014,2014,3 genes,de Castro-2014-The Involvement of the Mid1_Cch,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4405,PHI:3208,UniProt,G2WS91,GenBank,EGY13742,,,VdLs.17,VdMsb,,,,,,,27337,Verticillium dahliae,,Vd8,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,root; seedling,encodes a transmembrane mucin,,,MAPK signal pathway,reduced virulence,,,,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25151308,PubMed,10.1016/j.gene.2014.08.035,Gene. 2014 Oct 25;550(2):238-44,moelab@njau.edu.cn,VdMsb was found to be required for fungal virulence and microsclerotia production.,L Tian 2014,2014,1 gene,Tian-2014-VdMsb regulates virulence and micros,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4406,PHI:3208,UniProt,G2WS91,GenBank,EGY13742,,,VdLs.17,VdMsb,,,,,,,27337,Verticillium dahliae,,Vd8,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,encodes a transmembrane mucin,,,MAPK signal pathway,reduced virulence,,,,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25151308,PubMed,10.1016/j.gene.2014.08.035,Gene. 2014 Oct 25;550(2):238-44,moelab@njau.edu.cn,VdMsb was found to be required for fungal virulence and microsclerotia production.,L Tian 2014,2014,1 gene,Tian-2014-VdMsb regulates virulence and micros,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4407,PHI:3209,UniProt,A4KTQ9,GenBank,ABM63506,,,CBS 119.78,Pop1,,,,,,,312341,Ceratocystis harringtonii,,119.78,plane canker stain,eudicots,43335,Populus alba (related: white poplar),cv. Marte,,,leaf; stem,cerato-platanin,,,,reduced virulence,,,,,,,,,,no,,,,,,"pop1 behaved as PAMP, since it stimulated poplar leaf tissues to activate defence responses able to reduce consistently the C. populicola growth in non susceptible poplar plants.",functional test in host: direct injection,,,RP,19387635,PubMed,10.1007/s00253-009-1998-4,Appl Microbiol Biotechnol. 2009 Aug;84(2):309-22,aniello.scala@unifi.it,stem refers to tree trunk. Pathogen formerly called Ceratocystis populicola.,C Comparini 2009,2009,1 gene,Comparini-2009-New proteins orthologous to cer,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4408,PHI:3210,UniProt,S0E3H0,GenBank,CCT69384,,,IMI58289,FfSge1,,,,,,,5127,Fusarium fujikuroi,1279085,IMI58289,bakanae,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,morphological switch regulator,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25115968,PubMed,10.1111/1462-2920.12592,Environ Microbiol. 2014 Aug 12,tudzynsb@uni-muenster.de,The overexpression data revealed that the gene acts as a global activator of secondary metabolism.,C B Michielse 2014,2014,1 gene,Michielse-2014-The global regulator FfSge1 is,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4409,PHI:3211,UniProt,Q9HWS6,GenBank,AE004826_7,,,PAO1,BfmS,,"pEX18Ap::bfmSUD (1.8 kb gentamicin resistance cassette was cut from pPS858 with XbaI and then cloned into pEX18Ap::bfmSUD, yielding pEX18Ap::bfmSUGD)",,,,,287,Pseudomonas aeruginosa,1131757,MPAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,two-component sensor kinase,,,BfmS/BfmR/RhlR,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25166864,PubMed,10.1371/journal.ppat.1004340,PLoS Pathog. 2014 Aug 28;10(8):e1004340,jingzhao@nju.edu.cn,,Q Cao 2014,2014,1 gene,Cao-2014-A Novel Signal Transduction Pathway t,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4410,PHI:3212,UniProt,Q9HWS6,GenBank,AE004826_7,,,PAO1,BfmS,,"pEX18Ap::bfmSUD (1.8 kb gentamicin resistance cassette was cut from pPS858 with XbaI and then cloned into pEX18Ap::bfmSUD, yielding pEX18Ap::bfmSUGD)",,,,,287,Pseudomonas aeruginosa,1131757,MPAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,two-component sensor kinase,,,BfmS/BfmR/RhlR,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25166864,PubMed,10.1371/journal.ppat.1004340,PLoS Pathog. 2014 Aug 28;10(8):e1004340,jingzhao@nju.edu.cn,,Q Cao 2014,2014,1 gene,Cao-2014-A Novel Signal Transduction Pathway t,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4411,PHI:3213,UniProt,G4N8Y3,GenBank,EHA50277,,,70-15,MoCDIP1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23035914,PubMed,10.1094/MPMI-05-12-0117-R,Mol Plant Microbe Interact. 2013 Feb;26(2):191-202,wang.620@osu.edu,"MoCDIP1, MoCDIP3, MoCDIP4, and MoCDIP5, but not MoCDIP2 induce cell death in both monocot and dicot species.",So Chen 2013,2013,5 genes,Chen-2013-Identification and Characterization,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4412,PHI:3214,UniProt,G4MML4,GenBank,EHA57786,,,70-15,MoCDIP2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,secreted proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23035914,PubMed,10.1094/MPMI-05-12-0117-R,Mol Plant Microbe Interact. 2013 Feb;26(2):191-202,wang.620@osu.edu,"MoCDIP1, MoCDIP3, MoCDIP4, and MoCDIP5, but not MoCDIP2 induce cell death in both monocot and dicot species.",So Chen 2013,2013,5 genes,Chen-2013-Identification and Characterization,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4413,PHI:3215,UniProt,G4MX34,GenBank,EHA55132,,,70-15,MoCDIP3,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23035914,PubMed,10.1094/MPMI-05-12-0117-R,Mol Plant Microbe Interact. 2013 Feb;26(2):191-202,wang.620@osu.edu,"MoCDIP1, MoCDIP3, MoCDIP4, and MoCDIP5, but not MoCDIP2 induce cell death in both monocot and dicot species.",So Chen 2013,2013,5 genes,Chen-2013-Identification and Characterization,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4414,PHI:3216,UniProt,G4MVX4,GenBank,EHA55842,,,70-15,MoCDIP4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23035914,PubMed,10.1094/MPMI-05-12-0117-R,Mol Plant Microbe Interact. 2013 Feb;26(2):191-202,wang.620@osu.edu,"MoCDIP1, MoCDIP3, MoCDIP4, and MoCDIP5, but not MoCDIP2 induce cell death in both monocot and dicot species.",So Chen 2013,2013,5 genes,Chen-2013-Identification and Characterization,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4415,PHI:3217,,no data found,GenBank,XM_366014,,,,MoCDIP5,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23035914,PubMed,10.1094/MPMI-05-12-0117-R,Mol Plant Microbe Interact. 2013 Feb;26(2):191-202,wang.620@osu.edu,"MoCDIP1, MoCDIP3, MoCDIP4, and MoCDIP5, but not MoCDIP2 induce cell death in both monocot and dicot species.",So Chen 2013,2013,5 genes,Chen-2013-Identification and Characterization,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4416,PHI:3213,UniProt,G4N8Y3,GenBank,EHA50277,,,70-15,MoCDIP1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23035914,PubMed,10.1094/MPMI-05-12-0117-R,Mol Plant Microbe Interact. 2013 Feb;26(2):191-202,wang.620@osu.edu,"MoCDIP1, MoCDIP3, MoCDIP4, and MoCDIP5, but not MoCDIP2 induce cell death in both monocot and dicot species.",So Chen 2013,2013,5 genes,Chen-2013-Identification and Characterization,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4417,PHI:3214,UniProt,G4MML4,GenBank,EHA57786,,,70-15,MoCDIP2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,secreted proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23035914,PubMed,10.1094/MPMI-05-12-0117-R,Mol Plant Microbe Interact. 2013 Feb;26(2):191-202,wang.620@osu.edu,"MoCDIP1, MoCDIP3, MoCDIP4, and MoCDIP5, but not MoCDIP2 induce cell death in both monocot and dicot species.",So Chen 2013,2013,5 genes,Chen-2013-Identification and Characterization,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4418,PHI:3215,UniProt,G4MX34,GenBank,EHA55132,,,70-15,MoCDIP3,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23035914,PubMed,10.1094/MPMI-05-12-0117-R,Mol Plant Microbe Interact. 2013 Feb;26(2):191-202,wang.620@osu.edu,"MoCDIP1, MoCDIP3, MoCDIP4, and MoCDIP5, but not MoCDIP2 induce cell death in both monocot and dicot species.",So Chen 2013,2013,5 genes,Chen-2013-Identification and Characterization,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4419,PHI:3216,UniProt,G4MVX4,GenBank,EHA55842,,,70-15,MoCDIP4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23035914,PubMed,10.1094/MPMI-05-12-0117-R,Mol Plant Microbe Interact. 2013 Feb;26(2):191-202,wang.620@osu.edu,"MoCDIP1, MoCDIP3, MoCDIP4, and MoCDIP5, but not MoCDIP2 induce cell death in both monocot and dicot species.",So Chen 2013,2013,5 genes,Chen-2013-Identification and Characterization,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4420,PHI:3217,,no data found,GenBank,XM_366014,,,,MoCDIP5,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23035914,PubMed,10.1094/MPMI-05-12-0117-R,Mol Plant Microbe Interact. 2013 Feb;26(2):191-202,wang.620@osu.edu,"MoCDIP1, MoCDIP3, MoCDIP4, and MoCDIP5, but not MoCDIP2 induce cell death in both monocot and dicot species.",So Chen 2013,2013,5 genes,Chen-2013-Identification and Characterization,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4421,PHI:3218,UniProt,B2SJZ4,GenBank,ACD60511,,,PXO99A,RpoN2,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,flagellar motility,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25126992,PubMed,10.1016/j.micres.2014.07.002,Microbiol Res. 2014 Jul 27. pii: S0944-5013(14)00086-X,hechenyang@caas.cn,"The rpoN2 mutant, but not the fleQ mutant was impaired in its virulence on rice. In addition, the flagellin gene fliC mutant, which was non-motile, was not defective in virulence.",F Tian 2014,2014,3 genes,Tian-2014-Alternative sigma factor RpoN2 is re,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4422,PHI:3219,UniProt,Q5GZM8,GenBank,AAW75843,,,KACC 10331,fleQ,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,flagellar motility,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25126992,PubMed,10.1016/j.micres.2014.07.002,Microbiol Res. 2014 Jul 27. pii: S0944-5013(14)00086-X,hechenyang@caas.cn,"The rpoN2 mutant, but not the fleQ mutant was impaired in its virulence on rice. In addition, the flagellin gene fliC mutant, which was non-motile, was not defective in virulence.",F Tian 2014,2014,3 genes,Tian-2014-Alternative sigma factor RpoN2 is re,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4423,PHI:3220,UniProt,Q5GZN6,GenBank,AAW75835,,,KACC 10331,fliC,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,flagellar motility,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25126992,PubMed,10.1016/j.micres.2014.07.002,Microbiol Res. 2014 Jul 27. pii: S0944-5013(14)00086-X,hechenyang@caas.cn,"The rpoN2 mutant, but not the fleQ mutant was impaired in its virulence on rice. In addition, the flagellin gene fliC mutant, which was non-motile, was not defective in virulence.",F Tian 2014,2014,3 genes,Tian-2014-Alternative sigma factor RpoN2 is re,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4424,PHI:3221,UniProt,O74238,GenBank,AF074941,,,LAW96,SP1,,,,,,,13684,Parastagonospora nodorum,,LAW95,leaf blotch (wheat); glume blotch (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,encoding SnodProt1,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence,,,RP,,Not in PubMed,10.1006/pmpp.1999.0203,Hall et al. (1999) Physiological and Molecular Plant Pathology 55(1):69-73,john.hargreaves@bbsrc.ac.uk,"The role of SP1 in the pathogenicity of S.nodorumis unclear, but, the observation that this protein is produced and secreted during infection, and that homologues are present in other plant and human fungal pathogens suggests that it may have a role in determining the pathogenic habit and may, perhaps, be involved in adhesion to host cells or in the differentiation of infection structures.",N Hall 1999,1999,1 gene,Hall-1999-A homologue of a gene implicated in,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4425,PHI:3222,UniProt,Q5X177,GenBank,AAW75843,,,KACC 10331,lpp_2867,,,,,,,446,Legionella pneumophila,297246,Paris,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),ATCC 30234,,,,iron transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,25141909,PubMed,10.1111/1462-2920,Environ Microbiol. 2014 Aug 20,yann.hechard@univ-poitiers.fr,Mutants were defective for growth on iron depleted solid media and for ferrous iron uptake.,E Portier 2014,2014,1 gene,"Portier-2014-IroT_mavN, a new iron-regulated g",Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4426,PHI:3222,UniProt,Q5X177,GenBank,AAW75843,,,KACC 10331,lpp_2867,,,,,,,446,Legionella pneumophila,297246,Paris,Legionnaires' disease,primates,9606,Homo sapiens (related: human),U-937 cell line,,,macrophage,iron transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,25141909,PubMed,10.1111/1462-2920,Environ Microbiol. 2014 Aug 20,yann.hechard@univ-poitiers.fr,Mutants were defective for growth on iron depleted solid media and for ferrous iron uptake.,E Portier 2014,2014,1 gene,"Portier-2014-IroT_mavN, a new iron-regulated g",Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4427,PHI:3223,UniProt,G0X7E8,GenBank,AEK86680,,,RK209,pep1,,,,,,,5270,Ustilago maydis,,,smut,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,inhibitor of programmed cell death in host during infection,,,,reduced virulence,,no,no,yes,locally restricted chlorosis and no spreading necrotic lesions 6 days after inoculation.,,,reduced,,no,,,,,susceptibility,unaffected pathogeniticy in mutants; increased susceptibility in wildtype,gene mutation,,,RP,24329174,PubMed,10.1094/MPMI-10-13-0317-R,Mol Plant Microbe Interact. 2014 May;27(5):403-14,doehlemann@mpi-marburg.mpg.de,,A Hof 2014,2014,1 gene,Hof-2014-Alternative Cell Death Mechanisms Det,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4428,PHI:3224,UniProt,Q63K45,GenBank,CAH38994,,,K96243,BPSS1521 (bprD),,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,transcriptional regulator located in the type III secretion system (T3SS-3) operon,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,no,,gene deletion: full; gene complementation,,,RP,25111708,PubMed,10.1371/journal.pone.0104313,PLoS One. 2014 Aug 11;9(8):e104313,rasanaw@gmail.com,BALB/c mice infected with abprDmutant showed a shorter time to death and increased inflammation.,S Chirakul 2014,2014,1 gene,Chirakul-2014-Characterization of BPSS1521 (bp,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4429,PHI:3225,UniProt,T2C913,GenBank,AGV28620,,,CECT20795,Ndo1,,,,,,,36651,Penicillium digitatum,1170230,Pd1,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,naphthalene dioxygenase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,no,,gene deletion: full,,,RP,25099378,PubMed,10.1111/mpp.12179,Mol Plant Pathol. 2014 Aug 7,lgonzalez@iata.csic.es,,M Lopez-Perez 2014,2014,2 genes,Lopez-Perez-2014-Identification and functional,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4430,PHI:3226,UniProt,T2C7K6,GenBank,AGV28619,,,CECT20795,pnl1,,,,,,,36651,Penicillium digitatum,1170230,Pd1,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,pectin lyase,,,,reduced virulence,,,,,,,,,,,,,,,no,,gene deletion: full,,,RP,25099378,PubMed,10.1111/mpp.12179,Mol Plant Pathol. 2014 Aug 7,lgonzalez@iata.csic.es,,M Lopez-Perez 2014,2014,2 genes,Lopez-Perez-2014-Identification and functional,Batch041b,2014-09-01,MC,,,,,,,,,,,,,
,,Record 4431,PHI:3227,UniProt,Q9KLR1,GenBank,AAF96581,,,N16961,VCA0681,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4432,PHI:3228,UniProt,Q9KMV8,GenBank,AAF96122,,,N16961,VCA0210,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4433,PHI:3229,UniProt,Q9KPM7,GenBank,AAF95483,,,N16961,VC2340,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4434,PHI:3230,UniProt,Q9KSB1,GenBank,AAF94506,,,N16961,VC1348,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4435,PHI:3231,UniProt,Q9KL53,GenBank,AAF96792,,,N16961,VCA0895,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4436,PHI:3232,UniProt,Q9KSG1,GenBank,AAF94454,,,N16961,VC1295,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4437,PHI:3233,UniProt,Q9KL18,GenBank,AAF96828,,,N16961,VCA0931,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4438,PHI:3227,UniProt,Q9KLR1,GenBank,AAF96581,,,N16961,VCA0681,,,,,,PHI:3228; PHI:3229; PHI:3230; PHI:3231; PHI:3232; PHI:3233,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4439,PHI:3228,UniProt,Q9KMV8,GenBank,AAF96122,,,N16961,VCA0210,,,,,,PHI:3227; PHI:3229; PHI:3230; PHI:3231; PHI:3232; PHI:3233,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4440,PHI:3229,UniProt,Q9KPM7,GenBank,AAF95483,,,N16961,VC2340,,,,,,PHI:3227; PHI:3228; PHI:3230; PHI:3231; PHI:3232; PHI:3233,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4441,PHI:3230,UniProt,Q9KSB1,GenBank,AAF94506,,,N16961,VC1348,,,,,,PHI:3227; PHI:3228; PHI:3229; PHI:3231; PHI:3232; PHI:3233,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4442,PHI:3231,UniProt,Q9KL53,GenBank,AAF96792,,,N16961,VCA0895,,,,,,PHI:3227; PHI:3228; PHI:3229; PHI:3230; PHI:3232; PHI:3233,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4443,PHI:3232,UniProt,Q9KSG1,GenBank,AAF94454,,,N16961,VC1295,,,,,,PHI:3227; PHI:3228; PHI:3229; PHI:3230; PHI:3231; PHI:3233,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4444,PHI:3233,UniProt,Q9KL18,GenBank,AAF96828,,,N16961,VCA0931,,,,,,PHI:3227; PHI:3228; PHI:3229; PHI:3230; PHI:3231; PHI:3232,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,c-di-GMPphosphodiesterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25343965,PubMed,10.1186/s12866-014-0272-9,BMC Microbiol. 2014 Oct 25;14(1):272,rtamayo@med.unc.edu,,R W McKee 2014,2014,7 genes,McKee-2014-A systematic analysis of the in vit,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4445,PHI:3234,UniProt,G4NCG1,GenBank,EHA48258,,,70-15,MoLYS20,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,regulators of G-protein (GTP-binding protein) signaling (RGS) proteins/homocitrate synthase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25236475,PubMed,10.1002/pmic.201400173,Proteomics. 2014 Nov;14(21-22):2508-22,zhgzhang@njau.edu.cn,,H Zhang 2014,2014,1 gene,Zhang-2014-Comparative Proteomic Analyses Reve,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4446,PHI:3235,UniProt,Q4WY67,GenBank,EAL92386,,,Af293,pacC,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,pH-responsive transcription factor,,,,reduced virulence,,yes,,yes,,,,aberrant,,no,caspofungin,caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,RP,2532939,PubMed,10.1371/journal.ppat.1004413,PLoS Pathog. 2014 Oct 16;10(10):e1004413,elaine.bignell@manchester.ac.uk,DpacC mutants are hypersensitive to the cell wall-active drug caspofungin,M Bertuzzi 2014,2014,1 gene,Bertuzzi-2014-The pH-Responsive PacC Transcrip,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4447,PHI:3235,UniProt,Q4WY67,GenBank,EAL92386,,,Af293,pacC,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,pH-responsive transcription factor,,,,reduced virulence,,yes,,yes,,,,aberrant,,no,caspofungin,caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,RP,2532939,PubMed,10.1371/journal.ppat.1004413,PLoS Pathog. 2014 Oct 16;10(10):e1004413,elaine.bignell@manchester.ac.uk,DpacC mutants are hypersensitive to the cell wall-active drug caspofungin,M Bertuzzi 2014,2014,1 gene,Bertuzzi-2014-The pH-Responsive PacC Transcrip,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4448,PHI:3236,UniProt,J9VHR6,GenBank,AFR93748,,,H99,Aph1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"phosphate-regulated, secreted, and vacuolar acid phosphatase",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,25227465,PubMed,10.1128/mBio.01649-14,MBio. 2014 Sep 16;5(5):e01649-14,julianne.djordjevic@sydney.edu.au,,S Lev 2014,2014,1 gene,"Lev-2014-Identification of Aph1, a phosphate-r",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4449,PHI:3236,UniProt,J9VHR6,GenBank,AFR93748,,,H99,Aph1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,"phosphate-regulated, secreted, and vacuolar acid phosphatase",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,25227465,PubMed,10.1128/mBio.01649-14,MBio. 2014 Sep 16;5(5):e01649-14,julianne.djordjevic@sydney.edu.au,,S Lev 2014,2014,1 gene,"Lev-2014-Identification of Aph1, a phosphate-r",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4450,PHI:3237,UniProt,B0YDG4,GenBank,EDP47698,,,A1163,ctrA2,,,,,,,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,copper transporters,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; bathocuproine disulfonic acid,H2O2: CHEBI:16240; bathocuproine disulfonic acid: CHEBI:63934,,,,,gene deletion: full,,,RP,25281782,PubMed,10.1016/j.fgb.2014.09.008,Fungal Genet Biol. 2014 Oct 2. pii: S1087-1845(14)00165-0,cheolwony@korea.ac.kr,The ctrA2andctrCdouble-deletion mutant exhibited a growth defect onAspergillusminimal medium (AMM) supplemented with bathocuproine disulfonic acid (BCS) and was sensitive to H2O2.,Y Park 2014,2014,2 genes,Park-2014-Identification of high-affinity copp,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4451,PHI:3238,UniProt,B0XUP5,GenBank,EDP54030,,,A1163,ctrC,,,,,,,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,copper transporters,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; bathocuproine disulfonic acid,H2O2: CHEBI:16240; bathocuproine disulfonic acid: CHEBI:63934,,,,,gene deletion: full,,,RP,25281782,PubMed,10.1016/j.fgb.2014.09.008,Fungal Genet Biol. 2014 Oct 2. pii: S1087-1845(14)00165-0,cheolwony@korea.ac.kr,The ctrA2andctrCdouble-deletion mutant exhibited a growth defect onAspergillusminimal medium (AMM) supplemented with bathocuproine disulfonic acid (BCS) and was sensitive to H2O2.,Y Park 2014,2014,2 genes,Park-2014-Identification of high-affinity copp,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4452,PHI:3237,UniProt,B0YDG4,GenBank,EDP47698,,,A1163,ctrA2,,,,,,PHI:3238,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,copper transporters,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; bathocuproine disulfonic acid,H2O2: CHEBI:16240; bathocuproine disulfonic acid: CHEBI:63934,,,,,gene deletion: full,,,RP,25281782,PubMed,10.1016/j.fgb.2014.09.008,Fungal Genet Biol. 2014 Oct 2. pii: S1087-1845(14)00165-0,cheolwony@korea.ac.kr,The ctrA2andctrCdouble-deletion mutant exhibited a growth defect onAspergillusminimal medium (AMM) supplemented with bathocuproine disulfonic acid (BCS) and was sensitive to H2O2.,Y Park 2014,2014,2 genes,Park-2014-Identification of high-affinity copp,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4453,PHI:3238,UniProt,B0XUP5,GenBank,EDP54030,,,A1163,ctrC,,,,,,PHI:3237,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,copper transporters,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; bathocuproine disulfonic acid,H2O2: CHEBI:16240; bathocuproine disulfonic acid: CHEBI:63934,,,,,gene deletion: full,,,RP,25281782,PubMed,10.1016/j.fgb.2014.09.008,Fungal Genet Biol. 2014 Oct 2. pii: S1087-1845(14)00165-0,cheolwony@korea.ac.kr,The ctrA2andctrCdouble-deletion mutant exhibited a growth defect onAspergillusminimal medium (AMM) supplemented with bathocuproine disulfonic acid (BCS) and was sensitive to H2O2.,Y Park 2014,2014,2 genes,Park-2014-Identification of high-affinity copp,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4454,PHI:3239,UniProt,Q4PI58,GenBank,EAK81590,,,521,HSP12,,,,,,,5270,Ustilago maydis,,SG200,smut (maize),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,small heat shock proteins,,,,reduced virulence,,,,,small tumours and chlorosis,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,25251081,PubMed,10.1111/1574-6968.12605,FEMS Microbiol Lett. 2014 Sep 22,ghosh.anupama@jcbose.ac.in,The level of expression of small heat shock proteins induced upon H202 exposure is higher than that of regular heat shock proteins.,A Ghosh 2014,2014,3 genes,"Ghosh-2014-Small heat shock proteins (HSP12, H",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4455,PHI:3240,UniProt,Q4P7N2,GenBank,EAK85054,,,521,HSP20,,,,,,,5270,Ustilago maydis,,SG200,smut (maize),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,small heat shock proteins,,,,reduced virulence,,,,,small tumours and chlorosis,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,25251081,PubMed,10.1111/1574-6968.12605,FEMS Microbiol Lett. 2014 Sep 22,ghosh.anupama@jcbose.ac.in,The level of expression of small heat shock proteins induced upon H202 exposure is higher than that of regular heat shock proteins.,A Ghosh 2014,2014,3 genes,"Ghosh-2014-Small heat shock proteins (HSP12, H",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4456,PHI:3241,UniProt,Q4P6Y8,GenBank,EAK85153,,,521,HSP30,,,,,,,5270,Ustilago maydis,,SG200,smut (maize),monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,small heat shock proteins,,,,reduced virulence,,,,,small tumours and chlorosis,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,25251081,PubMed,10.1111/1574-6968.12605,FEMS Microbiol Lett. 2014 Sep 22,ghosh.anupama@jcbose.ac.in,The level of expression of small heat shock proteins induced upon H202 exposure is higher than that of regular heat shock proteins.,A Ghosh 2014,2014,3 genes,"Ghosh-2014-Small heat shock proteins (HSP12, H",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4457,PHI:3242,UniProt,H2FL17,GenBank,AEX88335,,,EB 92-3,rpfF,,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,signal factor-dependent quorum-sensing system that suppresses outer membrane vesicles,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25197068,PubMed,10.1073/pnas.1414944111,Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):E3910-8,icelab@berkeley.edu,"OMVs, production is suppressed by a quorum-sensing system, serve as an autoinhibitorofcelladhesiontosurfaces, thereby blocking attachment-driven biofilm formation that would restrict movement within the xylem and thus colonization of plants.",M Ionescu 2014,2014,1 gene,Ionescu-2014-Xylella fastidiosa outer membrane,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4458,PHI:3243,UniProt,Q02QT9,GenBank,ABJ12706,,,UCBPP-PA14,lsfA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; liver,1-Cys peroxiredoxin with thioldependent peroxidase activity,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide; paraquat,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; paraquat: CHEBI:34905,,,,,gene mutation: characterised; gene complementation,,,RP,25329795,PubMed,10.1371/journal.ppat.1004442,PLoS Pathog. 2014 Oct 16;10(10):e1004442,baldini@iq.usp.br,LsfA is important for oxidative stress resistance in P. aeruginosa,G H Kaihami 2014,2014,1 gene,Kaihami-2014-Involvement of a 1-cys peroxiredo,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4459,PHI:3244,,no data found,,,,,,MobZIP22,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,loss of pathogenicity,,no,yes,yes,no necrotic lesions formed,wild type,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4460,PHI:3245,,no data found,,,,,,MobZIP13,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,reduced virulence,,no,,,,aberrant,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4461,PHI:3246,,no data found,,,,,,MobZIP11,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,reduced virulence,,,no,,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4462,PHI:3247,,no data found,,,,,,MobZIP12,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4463,PHI:3248,,no data found,,,,,,MobZIP03,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,unaffected pathogenicity,,no,no,no,wild type,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4464,PHI:3249,,no data found,,,,,,MobZIP05,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,unaffected pathogenicity,,no,no,no,wild type,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4465,PHI:3250,,no data found,,,,,,MobZIP07,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,reduced virulence,,no,no,no,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4466,PHI:3251,,no data found,,,,,,MobZIP10,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,unaffected pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4467,PHI:3252,,no data found,,,,,,MobZIP14,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,reduced virulence,,yes,,,,aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4468,PHI:3253,,no data found,,,,,,MobZIP15,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,unaffected pathogenicity,,no,no,no,wild type,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4469,PHI:3254,,no data found,,,,,,MobZIP04,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,unaffected pathogenicity,,no,no,no,wild type,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4470,PHI:3255,,no data found,,,,,,MobZIP06,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,unaffected pathogenicity,,no,no,no,wild type,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4471,PHI:3256,,no data found,,,,,,MobZIP19,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,bZip transcription factor,,,,unaffected pathogenicity,,no,no,no,wild type,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,25314920,PubMed,10.1111/1462-2920.12633,Environ Microbiol. 2014 Oct 15,yonglee@snu.ac.kr,,S Kong 2014,2014,13 genes,Kong-2014-Systematic characterization of the b,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4472,PHI:3257,UniProt,G4MU34,GenBank,EHA55634,,,70-15,MoIlv1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,threonine deaminase,,,,reduced virulence,,yes,yes,yes,fewer and smaller lesions,reduced; aberrant,,reduced,,no,isoleucine,isoleucine: CHEBI:24898,,,,,gene deletion: full; gene complementation,,,RP,25307542,PubMed,10.1016/j.fgb.2014.10.001,Fungal Genet Biol. 2014 Oct 9. pii: S1087-1845(14)00184-4,hfzhang@njau.edu.cn,Exogenous isoleucine fully restores vegetative growth and partially restores conidiation and pathogenicity of the DMoilv1 mutant.,Y Du 2014,2014,1 gene,Du-2014-Threonine deaminase MoIlv1 is importan,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4473,PHI:3258,UniProt,Q4QGX0,GenBank,CAJ02958,,,Friedlin,C14DM,,,,,,,5664,Leishmania major,860569,lv39,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol biosynthesis,,,sterol biosynthesis,reduced virulence,,,,,,,,wild type,,no,itraconazole; amphotericin B,itraconazole: CHEBI:6076; amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,RP,25340392,PubMed,10.1371/journal.ppat.1004427,PLoS Pathog. 2014 Oct 23;10(10):e1004427,kai.zhang@ttu.edu,"The mutants showed severely reduced virulence in mice but were highly resistant to itraconazole and amphotericin B, two drugs targeting sterol synthesis.",W Xu 2014,2014,1 gene,Xu-2014-Sterol biosynthesis is required for he,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4474,PHI:3259,UniProt,Q4UQD0,GenBank,AAY50743,,,8004,XC_3703,,,,XC_2801,UniProt: Q4USX3,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,cyclic di-GMP effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25329577,PubMed,10.1371/journal.ppat.1004429.,PLoS Pathog. 2014 Oct 16;10(10):e1004429,rpryan@dundee.ac.uk,,S An 2014,2014,2 genes,An-2014-Novel Cyclic di-GMP Effectors of the Y,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4475,PHI:3260,UniProt,Q4USX3,GenBank,AAY49850,,,8004,XC_2801,,,,XC_3703,UniProt: Q4UQD0,PHI:3259,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,transcription regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25329577,PubMed,10.1371/journal.ppat.1004429.,PLoS Pathog. 2014 Oct 16;10(10):e1004429,rpryan@dundee.ac.uk,,S An 2014,2014,2 genes,An-2014-Novel Cyclic di-GMP Effectors of the Y,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4476,PHI:3259,UniProt,Q4UQD0,GenBank,AAY50743,,,8004,XC_3703,,,,XC_2801,UniProt: Q4USX3,PHI:3260,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,cyclic di-GMP effectors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25329577,PubMed,10.1371/journal.ppat.1004429.,PLoS Pathog. 2014 Oct 16;10(10):e1004429,rpryan@dundee.ac.uk,,S An 2014,2014,2 genes,An-2014-Novel Cyclic di-GMP Effectors of the Y,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4477,PHI:3261,UniProt,Q2A258,GenBank,CAJ79987,,,LVS,FTL_1548,,,,,,,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,disulfide bond isomerase substrates,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25257164,PubMed,10.1111/mmi.12808.Epub2014Oct20,Mol Microbiol. 2014 Nov;94(4):926-44,Jason.Huntley@UToledo.edu,,G Ren 2014,2014,2 genes,Ren-2014-Identification of disulfide bond isom,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4478,PHI:3262,UniProt,Q2A1R2,GenBank,CAJ80148,,,LVS,FTL_1709,,,,,,,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,disulfide bond isomerase substrates,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25257164,PubMed,10.1111/mmi.12808.Epub2014Oct20,Mol Microbiol. 2014 Nov;94(4):926-44,Jason.Huntley@UToledo.edu,,G Ren 2014,2014,2 genes,Ren-2014-Identification of disulfide bond isom,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4479,PHI:3263,UniProt,E9E8J3,GenBank,EFY87824,,,CQMa102,MaSnf1,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,,sucrose non-fermenting protein kinase,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,25213916,PubMed,10.1007/s00253-014-6066-z,Appl Microbiol Biotechnol. 2014 Sep 12,jinkai@cqu.edu.cn,,Y Ming 2014,2014,1 gene,"Ming-2014-MaSnf1, a sucrose non-fermenting pro",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4480,PHI:3264,UniProt,Q4P3F2,GenBank,EAK86610,,,521,lac1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Early Golden Bantam,,,leaf,putative laccase,,,,reduced virulence,,,,,,aberrant,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25226432,PubMed,10.1094/MPMI-05-14-0133-R,Mol Plant Microbe Interact. 2014 Sep 16,Scott.Gold@ars.usda.gov,The genes are involved in the melanin production especially during teliosporogenesis.,E Islamovic 2014,2014,2 genes,Islamovic-2014-Transcriptome analysis of a Ust,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4481,PHI:3265,UniProt,Q4P0E9,GenBank,EAK87187,,,521,pks1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Early Golden Bantam,,,leaf,polyketide synthase,,,,unaffected pathogenicity,,,,,,aberrant,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25226432,PubMed,10.1094/MPMI-05-14-0133-R,Mol Plant Microbe Interact. 2014 Sep 16,Scott.Gold@ars.usda.gov,The genes are involved in the melanin production especially during teliosporogenesis.,E Islamovic 2014,2014,2 genes,Islamovic-2014-Transcriptome analysis of a Ust,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4482,PHI:3266,UniProt,P13738,GenBank,AAA23448,,,,nhaA,,,,,,,562,Escherichia coli,362663,536,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,antiporter gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25268639,PubMed,10.1371/journal.pone.0108738,PLoS One. 2014 Sep 30;9(9):e108738,mathilde.lescat@inserm.fr,"The operon deletion had no differential impact between B2 and non-B2 strains, and did not result in a fitness modification in a murine model of gut colonization. Nevertheless, a murine model of septicemia revealed that recombination in nhaA among B2 strains was observed in strains with low virulence. Finally, nhaA and nhaAR operon deletions drastically decreased virulence in one B2 strain.",M Lescat 2014,2014,2 genes,Lescat-2014-The Conserved nhaAR Operon Is Dras,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4483,PHI:3267,UniProt,P0A9G2,GenBank,CAA27969,,,K-12,nhaR,,,,,,PHI:3266,562,Escherichia coli,362663,536,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,transcriptional activator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25268639,PubMed,10.1371/journal.pone.0108738,PLoS One. 2014 Sep 30;9(9):e108738,mathilde.lescat@inserm.fr,"The operon deletion had no differential impact between B2 and non-B2 strains, and did not result in a fitness modification in a murine model of gut colonization. Nevertheless, a murine model of septicemia revealed that recombination in nhaA among B2 strains was observed in strains with low virulence. Finally, nhaA and nhaAR operon deletions drastically decreased virulence in one B2 strain.",M Lescat 2014,2014,2 genes,Lescat-2014-The Conserved nhaAR Operon Is Dras,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4484,PHI:3266,UniProt,P13738,GenBank,AAA23448,,,,nhaA,,,,,,PHI:3267,562,Escherichia coli,362663,536,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,antiporter gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25268639,PubMed,10.1371/journal.pone.0108738,PLoS One. 2014 Sep 30;9(9):e108738,mathilde.lescat@inserm.fr,"The operon deletion had no differential impact between B2 and non-B2 strains, and did not result in a fitness modification in a murine model of gut colonization. Nevertheless, a murine model of septicemia revealed that recombination in nhaA among B2 strains was observed in strains with low virulence. Finally, nhaA and nhaAR operon deletions drastically decreased virulence in one B2 strain.",M Lescat 2014,2014,2 genes,Lescat-2014-The Conserved nhaAR Operon Is Dras,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4485,PHI:3268,UniProt,U3M7S2,GenBank,AGT97036,,,150,YraS,,,,,,,29486,Yersinia ruckeri,,150,enteric redmouth disease,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,,heat sensitive alkyl sulphatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25266819,PubMed,10.1186/s12866-014-0221-7,BMC Microbiol. 2014 Sep 30;14(1):221,jaga@uniovi.es,The yraS mutant showed a similar level of SDS resistance to the parental strain.,R Navais 2014,2014,1 gene,Navais-2014-The heat sensitive factor (HSF) of,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4486,PHI:3269,UniProt,Q8E473,GenBank,4MBO_A,,,NEM316,xf,,,,,,,1311,Streptococcus agalactiae,1203670,GD201008-001,neonatal pneumonia; neonatal meningitis; bovine mastitis; meningoencephalitis (fish),bony fishes,7955,Danio rerio (related: zebrafish),,,,,surface protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25344337,PubMed,10.1186/s12917-014-0259-7,BMC Vet Res. 2014 Oct 26;10(1):259,lucp@njau.edu.cn,The 50% lethal dose ofdeltaxfwas increased (4-fold) compared with that of the parental strain in a zebrafish infection model.,G Liu 2014,2014,1 gene,Liu-2014-Identification of a virulence-related,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4487,PHI:3270,UniProt,J5K8Q8,GenBank,EJP70506,,,Bmh1,ARSEF 2860,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,contribute to the fundamental biology and physiology.,,,Ras/MAPK signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,H2O2; menadione; Congo red; sodium dodecyl sulfate (SDS); NaCl,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene disruption; gene complementation,,,RP,25315061,PubMed,10.1111/1462-2920.12634,Environ Microbiol. 2014 Oct 15,mgfeng@zju.edu.cn,,Q Liu 2014,2014,2 genes,Liu-2014-Unveiling equal importance of two 14-,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4488,PHI:3271,UniProt,J4UI12,GenBank,EJP63017,,,Bmh2,ARSEF 2860,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,contribute to the fundamental biology and physiology.,,,Ras/MAPK signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,H2O2; menadione; Congo red; sodium dodecyl sulfate (SDS); NaCl,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene disruption; gene complementation,,,RP,25315061,PubMed,10.1111/1462-2920.12634,Environ Microbiol. 2014 Oct 15,mgfeng@zju.edu.cn,,Q Liu 2014,2014,2 genes,Liu-2014-Unveiling equal importance of two 14-,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4489,PHI:3270,UniProt,J5K8Q8,GenBank,EJP70506,,,Bmh1,ARSEF 2860,,,,,,PHI:3271,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,contribute to the fundamental biology and physiology.,,,Ras/MAPK signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,H2O2; menadione; Congo red; sodium dodecyl sulfate (SDS); NaCl,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,altered gene expression / gene regulation: silencing,,,RP,25315061,PubMed,10.1111/1462-2920.12634,Environ Microbiol. 2014 Oct 15,mgfeng@zju.edu.cn,,Q Liu 2014,2014,2 genes,Liu-2014-Unveiling equal importance of two 14-,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4490,PHI:3271,UniProt,J4UI12,GenBank,EJP63017,,,Bmh2,ARSEF 2860,,,,,,PHI:3270,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,contribute to the fundamental biology and physiology.,,,Ras/MAPK signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,H2O2; menadione; Congo red; sodium dodecyl sulfate (SDS); NaCl,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,altered gene expression / gene regulation: silencing,,,RP,25315061,PubMed,10.1111/1462-2920.12634,Environ Microbiol. 2014 Oct 15,mgfeng@zju.edu.cn,,Q Liu 2014,2014,2 genes,Liu-2014-Unveiling equal importance of two 14-,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4491,PHI:3272,UniProt,Q8CWG4,GenBank,AE013994_1,,,KIM10+,glpD,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,glycerol-3-phosphate dehydrogenase involved in glycerol fermentation,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25220241,PubMed,10.1016/j.micpath.2014.08.010,Microb Pathog. 2014 Sep 16;76C:33-43,vlmotin@utmb.edu,Chromosomal restoration ofglpDin CO92 resulted in a significant increase in biofilm formation.,S P Willias 2014,2014,1 gene,Willias-2014-Functional characterization of Ye,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4492,PHI:3273,UniProt,X8AYS1,GenBank,EUA37082,,,2285 (R),oppA,,,,MAV_2941; MAV_4320,"MAV_2941, UniProt: A0A0H3A0D8; MAV_4320, UniProt: A0A0H3A5M5",,1764,Mycobacterium avium,,au2,disseminated disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,transport of oligopeptides across the cell membrane,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25245008,PubMed,10.1016/j.micpath.2014.09.010,Microb Pathog. 2014 Sep 20;76C:67-76,luiz.bermudez@oregonstate.edu,Mutation in the transport domain of theoppA gene resulted in bacterial attenuation in both macrophages and in mice.,L Danelishvili 2014,2014,1 gene,Danelishvili-2014-Identification of Mycobacter,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4493,PHI:3274,UniProt,W2E906,GenBank,ETK27267,,,DSM 25719,dhbF,,,,,,,1464,Paenibacillus larvae,697284,subsp. larvae strain DSM 25430,American foulbrood,bees,7460,Apis mellifera (related: honey bee),,,,larva,siderophore bacillibactin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25237888,PubMed,10.1371/journal.pone.0108272,PLoS One. 2014 Sep 19;9(9):e108272,elke.genersch@rz.hu-berlin.de,Mutants showed a reduction in siderophore production.,G Hertlein 2014,2014,1 gene,Hertlein-2014-Production of the Catechol Type,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4494,PHI:3275,UniProt,Q4W9X3,GenBank,EAL84490,,,Af293,fhpA,,,,,,PHI:3277,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,flavohemoglobins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25309516,PubMed,10.3389/fmicb.2014.00469,Front Microbiol. 2014 Sep 11;5:469,axel.brakhage@hki-jena.de,All mutant strains tested displayed wild-type pathogenicity.,K Lapp 2014,2014,3 genes,Lapp-2014-Characterization of the Aspergillus,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4495,PHI:3277,UniProt,Q4WIQ3,GenBank,EAL87202,,,Af293,gnoA,,,,,,PHI:3275,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,S-nitrosoglutathione reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25309516,PubMed,10.3389/fmicb.2014.00469,Front Microbiol. 2014 Sep 11;5:469,axel.brakhage@hki-jena.de,All mutant strains tested displayed wild-type pathogenicity.,K Lapp 2014,2014,3 genes,Lapp-2014-Characterization of the Aspergillus,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4496,PHI:3276,UniProt,Q4WC12,GenBank,EAL85372,,,Af293,fhpB,,,,,,PHI:3275,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,flavohemoglobins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25309516,PubMed,10.3389/fmicb.2014.00469,Front Microbiol. 2014 Sep 11;5:469,axel.brakhage@hki-jena.de,All mutant strains tested displayed wild-type pathogenicity.,K Lapp 2014,2014,3 genes,Lapp-2014-Characterization of the Aspergillus,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4497,PHI:3275,UniProt,Q4W9X3,GenBank,EAL84490,,,Af293,fhpA,,,,,,PHI:3276,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,flavohemoglobins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25309516,PubMed,10.3389/fmicb.2014.00469,Front Microbiol. 2014 Sep 11;5:469,axel.brakhage@hki-jena.de,All mutant strains tested displayed wild-type pathogenicity.,K Lapp 2014,2014,3 genes,Lapp-2014-Characterization of the Aspergillus,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4498,PHI:3278,UniProt,N4V0R3,GenBank,ENH81573,,,MAFF 240422,CoIra1,,,,,,,5465,Colletotrichum orbiculare,1213857,MAFF240422,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),,,,cotyledon,Ras GTPase activating protein,,,cAMP signaling,reduced virulence,,yes,,,,aberrant; reduced,,aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,25275394,PubMed,10.1371/journal.pone.0109045,PLoS One. 2014 Oct 2;9(9):e109045,y_kubo@kpu.ac.jp,CoIra1 is involved in infection-related morphogenesis and pathogenicity by proper regulation of cAMP and MAPK signaling pathways through CoRas2.,K Harata 2014,2014,3 genes,Harata-2014-Ras GTPase Activating Protein CoIr,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4499,PHI:3279,UniProt,N4UYN1,GenBank,ENH80898,,,MAFF 240422,CoRAS2,,,,,,,5465,Colletotrichum orbiculare,1213857,MAFF240422,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),,,,cotyledon,Ras genes,,,cAMP signaling,reduced virulence,,,,,,,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,25275394,PubMed,10.1371/journal.pone.0109045,PLoS One. 2014 Oct 2;9(9):e109045,y_kubo@kpu.ac.jp,CoIra1 is involved in infection-related morphogenesis and pathogenicity by proper regulation of cAMP and MAPK signaling pathways through CoRas2.,K Harata 2014,2014,3 genes,Harata-2014-Ras GTPase Activating Protein CoIr,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4500,PHI:3280,UniProt,N4VQQ5,GenBank,ENH84705,,,MAFF 240422,CoRAS1,,,,,,,5465,Colletotrichum orbiculare,1213857,MAFF240422,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),,,,cotyledon,Ras genes,,,cAMP signaling,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full; gene complementation,,,RP,25275394,PubMed,10.1371/journal.pone.0109045,PLoS One. 2014 Oct 2;9(9):e109045,y_kubo@kpu.ac.jp,CoIra1 is involved in infection-related morphogenesis and pathogenicity by proper regulation of cAMP and MAPK signaling pathways through CoRas2.,K Harata 2014,2014,3 genes,Harata-2014-Ras GTPase Activating Protein CoIr,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4501,PHI:3281,UniProt,A0A097IB07,GenBank,AIT59279,,,Yb2,AS87_04050,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,fibrinous serositis; caseous salpingitis; vegetative disorder,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,lipopolysaccharide biosynthesis and pathogenicity,,,,reduced virulence,,,,,,,,aberrant,,no,triton X-100; H2O2; ampicillin; streptomycin sulfate; gentamicin; spectinomycin sulfate; chloramphenicol; polymyxin B; nalidixic acid,Triton X-100: CHEBI:9750; H2O2: CHEBI:16240; ampicillin: CHEBI:28971; streptomycin sulfate: CHEBI:32158; gentamicin: CHEBI:17833; spectinomycin sulfate: CAS:23312-56-3; chloramphenicol: CHEBI:17698; polymyxin B: CHEBI:8309; nalidixic acid: CHEBI:100147,,,,,gene mutation: characterised; gene complementation,,,RP,25303276,PubMed,10.1371/journal.pone.0109962,PLoS One. 2014 Oct 10;9(10):e109962,yus@shvri.ac.cn,"Mutants showed higher sensitivity to antibiotics, disinfectants and normal duck serum, and higher capability of adherence and invasion to Vero cells, compared to its wild-type strain.",X Wang 2014,2014,1 gene,Wang-2014-The AS87_04050 Gene Is Involved in B,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4502,PHI:3282,UniProt,Q4USG7,GenBank,AAY50006,,,8004,NagZ,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain Xc17,black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,b-lactamase induction,,,,reduced virulence,,,,,,,,,,no,ampicillin; ticarcillin; carbenicillin; cefuroxime,ampicillin: CHEBI:28971; ticarcillin: CHEBI:9587; carbenicillin: CHEBI:3393; cefuroxime: CHEBI:3515,,,,,gene disruption; gene complementation,,,RP,25229604,PubMed,10.1016/j.resmic.2014.08.008,Res Microbiol. 2014 Sep 16. pii: S0923-2508(14)00138-7,rmhu@asia.edu.tw,Loss of nagZxc increased the susceptibility of Xc17 to b-lactam antibiotics,T Yang 2014,2014,2 genes,Yang-2014-NagZ is required for beta-lactamase,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4503,PHI:3283,UniProt,Q8P471,GenBank,AAM43076,,,ATCC 33913,ampG,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain Xc17,black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,b-lactamase induction,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25229604,PubMed,10.1016/j.resmic.2014.08.008,Res Microbiol. 2014 Sep 16. pii: S0923-2508(14)00138-7,rmhu@asia.edu.tw,,T Yang 2014,2014,2 genes,Yang-2014-NagZ is required for beta-lactamase,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4504,PHI:3284,UniProt,Q9HWK6,GenBank,AAL47683,,,PA103-29,Protease IV,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,a quorum sensing-dependent protease,,,Toll signaling pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,25315216,PubMed,10.1111/mmi.12830,Mol Microbiol. 2014 Oct 15,joonhee@pusan.ac.kr,"Protease IV, a QS-regulated exoprotease of P. aeruginosa functions as a key virulence effector causing the melanization and death of T. molitor larvae.",S Park 2014,2014,1 gene,"Park-2014-Protease IV, a quorum sensing-depend",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4505,PHI:3284,UniProt,Q9HWK6,GenBank,AAL47683,,,PA103-29,Protease IV,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,crustaceans,85549,Artemia salina (no common name found),,,,larva,a quorum sensing-dependent protease,,,Toll signaling pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,25315216,PubMed,10.1111/mmi.12830,Mol Microbiol. 2014 Oct 15,joonhee@pusan.ac.kr,"Protease IV, a QS-regulated exoprotease of P. aeruginosa functions as a key virulence effector causing the melanization and death of T. molitor larvae.",S Park 2014,2014,1 gene,"Park-2014-Protease IV, a quorum sensing-depend",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4506,PHI:3284,UniProt,Q9HWK6,GenBank,AAL47683,,,PA103-29,Protease IV,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,a quorum sensing-dependent protease,,,Toll signaling pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,25315216,PubMed,10.1111/mmi.12830,Mol Microbiol. 2014 Oct 15,joonhee@pusan.ac.kr,"Protease IV, a QS-regulated exoprotease of P. aeruginosa functions as a key virulence effector causing the melanization and death of T. molitor larvae.",S Park 2014,2014,1 gene,"Park-2014-Protease IV, a quorum sensing-depend",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4507,PHI:3285,UniProt,Q6GFE2,GenBank,CAG40992,,,MRSA252,saNOS,,nos::erm,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney; heart; lung,NO-synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25275514,PubMed,10.1371/journal.pone.0108868,PLoS One. 2014 Oct 2;9(9):e108868,kcrice@ufl.edu,"The significance of the operon organization ofnos-pdt and potential relationship between these two enzymes remains to be elucidated, but initial explorations presented.",A M Sapp 2014,2014,1 gene,Sapp-2014-Contribution of the nos-pdt Operon t,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4508,PHI:3286,UniProt,Q6FRH8,GenBank,CAG60099,,,CBS 138,CgVPS15,chromosome H,,,,,,5478,Candida glabrata,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; liver; brain,class III phosphoinositide 3-kinase,,,PI3K signalling,reduced virulence,,,,,,,,reduced,,no,H2O2; menadione; sodium dodecyl sulfate (SDS); NaCl; hydroxyurea,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sodium dodecyl sulfate (SDS): CHEBI:8984; hydroxyurea: CHEBI:44423,,,,,gene deletion: full,,,RP,25223215,PubMed,10.1111/cmi.12364,Cell Microbiol. 2014 Sep 16,rkaur@cdfd.org.in,"Components of PI3K signalling are eesential in modulation of host immune response, intracellular survival, stress tolerance and virulence in C. glabrata.",M N Rai 2014,2014,2 genes,Rai-2014-An essential role for phosphatidylino,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4509,PHI:3287,UniProt,Q6FSR7,GenBank,CAG59654,,,CBS 138,CgVps34,chromosome G,,,,,,5478,Candida glabrata,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; liver; brain,catalytic subunit of the C. glabrata PI3K complex,,,PI3K signalling,reduced virulence,,,,,,,,reduced,,no,H2O2; menadione; sodium dodecyl sulfate (SDS); NaCl; hydroxyurea,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sodium dodecyl sulfate (SDS): CHEBI:8984; hydroxyurea: CHEBI:44423,,,,,gene deletion: full,,,RP,25223215,PubMed,10.1111/cmi.12364,Cell Microbiol. 2014 Sep 16,rkaur@cdfd.org.in,"Components of PI3K signalling are eesential in modulation of host immune response, intracellular survival, stress tolerance and virulence in C. glabrata.",M N Rai 2014,2014,2 genes,Rai-2014-An essential role for phosphatidylino,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4510,PHI:3289,UniProt,H8HAJ5,GenBank,AFC66130,,,MGAS15252,HylA,,,,,,,1314,Streptococcus pyogenes,404331,serotype M4,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,hyaluronate lyase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25266727,PubMed,10.1074/jbc.M114.602847,J Biol Chem. 2014 Nov 14;289(46):32303-15,jncole@ucsd.edu,"Capsule enhances M4 GAS plasmin activity and neutrophil survival, but has no effect on in vivo virulence.",A Henningham 2014,2014,1 gene,Henningham-2014-Mutual Exclusivity of Hyaluron,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4511,PHI:3290,UniProt,Q02N79,GenBank,ABJ11810,,,UCBPP-PA14,pqsH,,,,,,,287,Pseudomonas aeruginosa,1131757,MPAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,kidney; bladder,quorum sensing system to regulate several genes required for its survival and pathogenicity within the host.,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25240873,PubMed,10.1016/j.ijmm.2014.08.013,Int J Med Microbiol. 2014 Sep 1. pii: S1438-4221(14)00112-X,kusum harjai@hotmail.com,"Significant reduction in the log count, mild tissue damage and declined levels of pathological markers were observed in mice infected with mutant strains as compared to MPAO1.",A Bala 2014,2014,2 genes,Bala-2014-Pseudomonas quinolone signalling sys,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4512,PHI:3291,UniProt,Q9I4X3,GenBank,AE004532_9,,,PAO1,pqsA,,,,,,,287,Pseudomonas aeruginosa,1131757,MPAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,kidney; bladder,quorum sensing system to regulate several genes required for its survival and pathogenicity within the host.,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25240873,PubMed,10.1016/j.ijmm.2014.08.013,Int J Med Microbiol. 2014 Sep 1. pii: S1438-4221(14)00112-X,kusum harjai@hotmail.com,"Significant reduction in the log count, mild tissue damage and declined levels of pathological markers were observed in mice infected with mutant strains as compared to MPAO1.",A Bala 2014,2014,2 genes,Bala-2014-Pseudomonas quinolone signalling sys,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4513,PHI:3292,UniProt,A0A077D1S9,GenBank,AIL24425,,,Cg-14,AREB,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,anthracnose,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,regulation of PACC-dependent acid-expressed-genes and pathogenicity.,,,,reduced virulence,,,,,,,,wild type,wild type,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25317668,PubMed,10.1094/MPMI-09-14-0252-R,Mol Plant Microbe Interact. 2014 Oct 15,dovprusk@agri.gov.il,The areB mutants showed significantly reduced ammonia secretion and pathogenicity on tomato fruits.,D Ment 2014,2014,1 gene,Ment-2014-A role of AREB in the Regulation of,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4514,PHI:3293,UniProt,C6GMR2,GenBank,CAZ51773,,,SC84,spxA1,,pSET4s::spxA1,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; spleen,global regulators involved in stress tolerance and virulence.,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; sodium dodecyl sulfate (SDS); NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,RP,25264876,PubMed,10.1371/journal.pone.0108197,PLoS One. 2014 Sep 29;9(9):e108197,beiwc@mail.hzau.edu.cn,"deltaspxA1 exhibited impaired growth in the presence of hydrogen peroxide, while deltaspxA2 exhibited impaired growth in the presence of SDS and NaCl.",C Zheng 2014,2014,2 genes,Zheng-2014-Two Spx Regulators Modulate Stress,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4515,PHI:3294,UniProt,C6GPY2,GenBank,CAZ50835,,,SC84,spxA2,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; spleen,global regulators involved in stress tolerance and virulence.,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; sodium dodecyl sulfate (SDS); NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,RP,25264876,PubMed,10.1371/journal.pone.0108197,PLoS One. 2014 Sep 29;9(9):e108197,beiwc@mail.hzau.edu.cn,"deltaspxA1 exhibited impaired growth in the presence of hydrogen peroxide, while deltaspxA2 exhibited impaired growth in the presence of SDS and NaCl.",C Zheng 2014,2014,2 genes,Zheng-2014-Two Spx Regulators Modulate Stress,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4516,PHI:3295,UniProt,Q8PG84,GenBank,AAM38576,,,306,XbmR,,,,,,,346,Xanthomonas citri,611301,subsp. citri,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Macfadyen,,,leaf,transcriptional activator of the NtrC family,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25346091,PubMed,10.1111/1462-2920.12684,Environ Microbiol. 2014 Oct 24,,"Mutants resulted in impaired structural development of the Xcc biofilm, loss of chemotaxis and reduced virulence in grapefruit plants.",P M Yaryura 2014,2014,1 gene,"Yaryura-2014-XbmR, a new transcription factor",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4517,PHI:3296,UniProt,H3RJF6,GenBank,EHT98413,,,DC283,iucA,,,,,,,66269,Pantoea stewartii,660596,subsp. stewartii strain DC283,Stewart's wilt (sweet corn),monocots,4577,Zea mays (related: maize),cv. Jubilee,,,leaf,siderophore-mediated iron acquisition,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25326304,PubMed,10.1128/AEM.02503-14,Appl Environ Microbiol. 2014 Oct 17. pii: AEM.02503-14,mcroper@ucr.edu,,L Burbank 2014,2014,2 genes,Burbank-2014-Siderophore-mediated iron acquisi,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4518,PHI:3297,UniProt,H3RJF2,GenBank,EHT98409,,,DC283,iutA,,,,,,,66269,Pantoea stewartii,660596,subsp. stewartii strain DC283,Stewart's wilt (sweet corn),monocots,4577,Zea mays (related: maize),cv. Jubilee,,,leaf,siderophore-mediated iron acquisition,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25326304,PubMed,10.1128/AEM.02503-14,Appl Environ Microbiol. 2014 Oct 17. pii: AEM.02503-14,mcroper@ucr.edu,,L Burbank 2014,2014,2 genes,Burbank-2014-Siderophore-mediated iron acquisi,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4519,PHI:3298,UniProt,Q8PI49,GenBank,AAM37894,,,306,VrpA,,,,HrcJ; HrcC,"HrcJ, UniProt: Q8PQB9; HrcC, UniProt: Q8PQB3",,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,leaf,contributes to efficient protein secretion by type III secretion system,,,,loss of pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25338144,PubMed,10.1094/MPMI-10-14-0309-R,Mol Plant Microbe Interact. 2014 Oct 22,nianwang@ufl.edu,VrpA is involved in Xac tolerance of oxidative stress.,X Zhou 2014,2014,1 gene,Zhou-2014-A novel periplasmic protein VrpA con,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4520,PHI:3298,UniProt,Q8PI49,GenBank,AAM37894,,,306,VrpA,,,,HrcJ; HrcC,"HrcJ, UniProt: Q8PQB9; HrcC, UniProt: Q8PQB3",,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,contributes to efficient protein secretion by type III secretion system,,,,loss of pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25338144,PubMed,10.1094/MPMI-10-14-0309-R,Mol Plant Microbe Interact. 2014 Oct 22,nianwang@ufl.edu,VrpA is involved in Xac tolerance of oxidative stress.,X Zhou 2014,2014,1 gene,Zhou-2014-A novel periplasmic protein VrpA con,Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4521,PHI:3299,UniProt,A0A075TRC0,GenBank,AIG62146,,,NRRL 35695,patK,,,,,,,27334,Penicillium expansum,,PEX1,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,production of patulin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25338147,PubMed,10.1094/MPMI-09-14-0261-FI,Mol Plant Microbe Interact. 2014 Oct 22,tgabaldon@crg.es,Knockout mutants clearly demonstrated that neither patulin nor citrinin are required by P. expansum to successfully infect apples.,A Ballester 2014,2014,6 genes,"Ballester-2014-Genome, transcriptome, and func",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4522,PHI:3300,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,patL,,,,,,,27334,Penicillium expansum,,PEX1,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,production of patulin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25338147,PubMed,10.1094/MPMI-09-14-0261-FI,Mol Plant Microbe Interact. 2014 Oct 22,tgabaldon@crg.es,Knockout mutants clearly demonstrated that neither patulin nor citrinin are required by P. expansum to successfully infect apples.,A Ballester 2014,2014,6 genes,"Ballester-2014-Genome, transcriptome, and func",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4523,PHI:3301,UniProt,A0A075TRB3,GenBank,AIG62141,,,NRRL 35695,patN,,,,,,,27334,Penicillium expansum,,PEX1,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,production of patulin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25338147,PubMed,10.1094/MPMI-09-14-0261-FI,Mol Plant Microbe Interact. 2014 Oct 22,tgabaldon@crg.es,Knockout mutants clearly demonstrated that neither patulin nor citrinin are required by P. expansum to successfully infect apples.,A Ballester 2014,2014,6 genes,"Ballester-2014-Genome, transcriptome, and func",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4524,PHI:3302,,no data found,GenBank,KGO36753,,,d1,PEXP_005520,,,,,,,27334,Penicillium expansum,,PEX1,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,production of citrinin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25338147,PubMed,10.1094/MPMI-09-14-0261-FI,Mol Plant Microbe Interact. 2014 Oct 22,tgabaldon@crg.es,Knockout mutants clearly demonstrated that neither patulin nor citrinin are required by P. expansum to successfully infect apples.,A Ballester 2014,2014,6 genes,"Ballester-2014-Genome, transcriptome, and func",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4525,PHI:3303,,no data found,GenBank,KGO69364,,,CMP-1,PEX1_010420,,,,,,,27334,Penicillium expansum,,PEX1,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,production of citrinin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25338147,PubMed,10.1094/MPMI-09-14-0261-FI,Mol Plant Microbe Interact. 2014 Oct 22,tgabaldon@crg.es,Knockout mutants clearly demonstrated that neither patulin nor citrinin are required by P. expansum to successfully infect apples.,A Ballester 2014,2014,6 genes,"Ballester-2014-Genome, transcriptome, and func",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4526,PHI:3304,,no data found,GenBank,KGO60781,,,MD-8,PEX2_100460,,,,,,,27334,Penicillium expansum,,PEX1,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,production of citrinin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25338147,PubMed,10.1094/MPMI-09-14-0261-FI,Mol Plant Microbe Interact. 2014 Oct 22,tgabaldon@crg.es,Knockout mutants clearly demonstrated that neither patulin nor citrinin are required by P. expansum to successfully infect apples.,A Ballester 2014,2014,6 genes,"Ballester-2014-Genome, transcriptome, and func",Batch042,2014-11-01,MC,,,,,,,,,,,,,
,,Record 4527,PHI:3305,UniProt,Q2G2U9,GenBank,AF515775_2,,,,sarA,,,,,,,1280,Staphylococcus aureus,,LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),NIH Swiss,,,heart; spleen; kidney,production of extracellular proteases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25257373,PubMed,10.1002/mbo3.214,Microbiologyopen. 2014 Dec;3(6):897-909,smeltzermarks@uams.edu,,A J Loughran 2014,2014,1 gene,Loughran-2014-Impact of individual extracellul,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4528,PHI:3306,UniProt,Q2YKK7,GenBank,AIK05883,,,3196,LovhK,chromosome 2,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,flavin-binding sensor histidine kinase,,,general stress response signalling pathway,loss of pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation: characterised; gene complementation,,,RP,25257300,PubMed,10.1111/mmi.12809,Mol Microbiol. 2014 Nov;94(4):913-25,scrosson@uchicago.edu,Mutants are sensitive to oxidative and acidic stress,H Kim 2014,2014,1 gene,Kim-2014-The Brucella abortus virulence regula,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4529,PHI:3307,UniProt,G4NII8,GenBank,EHA48048,,,70-15,gpf1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,Zn2Cys6 transcription factors,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4530,PHI:3308,UniProt,G4NLB5,GenBank,EHA45997,,,70-15,cnf1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,Zn2Cys6 transcription factors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4531,PHI:3309,UniProt,G4NJD7,GenBank,EHA46353,,,70-15,cnf2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,Zn2Cys6 transcription factors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4532,PHI:3310,UniProt,G4MKH9,GenBank,EHA57568,,,70-15,Mocod1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,Zn2Cys6 transcription factors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4533,PHI:3311,UniProt,G4NGB1,GenBank,EHA47068,,,70-15,pcf1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,Zn2Cys6 transcription factors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4534,PHI:3308,UniProt,G4NLB5,GenBank,EHA45997,,,70-15,cnf1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Zn2Cys6 transcription factors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4535,PHI:3309,UniProt,G4NJD7,GenBank,EHA46353,,,70-15,cnf2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Zn2Cys6 transcription factors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4536,PHI:3312,UniProt,G4MT75,GenBank,EHA55540,,,70-15,gta1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Zn2Cys6 transcription factors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4537,PHI:3313,UniProt,G4NII8,GenBank,EHA48048,,,70-15,gpf1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Zn2Cys6 transcription factors,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4538,PHI:3314,UniProt,G4MNN4,GenBank,EHA57940,,,70-15,cca1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Zn2Cys6 transcription factors,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4539,PHI:3310,UniProt,G4MKH9,GenBank,EHA57568,,,70-15,Mocod1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Zn2Cys6 transcription factors,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4540,PHI:3315,UniProt,G4MT41,GenBank,EHA55506,,,70-15,conx1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Zn2Cys6 transcription factors,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4541,PHI:3316,UniProt,G4MZS3,GenBank,EHA55437,,,70-15,gcc1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Zn2Cys6 transcription factors,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full,,,RP,25299517,PubMed,10.1371/journal.ppat.1004432,Mol Microbiol. 2014 Nov;94(4):913-25,plu@zju.edu.cn,,J Lu 2014,2014,10 genes,Lu-2014-Systematic Analysis of Zn2Cys6 Transcr,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4542,PHI:3317,UniProt,B8F4W8,GenBank,ACL32370,,,SH0165,hsdR,,,,,,,738,Glaesserella parasuis,,LC,Glasser's disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; spleen; lung,involved in pathogenicity,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence,,,RP,25283960,PubMed,10.1016/j.micpath.2014.10.001,Microb Pathog. 2014 Dec;77C:17-23,jinbaowang@aliyun.com,Pathogen formerly called Haemophilus parasuis,J Yu 2014,2014,4 genes,Yu-2014-Identification of putative virulence-a,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4543,PHI:3318,,no data found,,ZP_10128492.1,,,,hsdS,,,,,,,738,Glaesserella parasuis,,LC,Glasser's disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; spleen; lung,involved in pathogenicity,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence,,,RP,25283960,PubMed,10.1016/j.micpath.2014.10.001,Microb Pathog. 2014 Dec;77C:17-23,jinbaowang@aliyun.com,Pathogen formerly called Haemophilus parasuis,J Yu 2014,2014,4 genes,Yu-2014-Identification of putative virulence-a,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4544,PHI:3319,UniProt,B8F4F0,GenBank,ACL32202,,,SH0165,gpT,,,,,,,738,Glaesserella parasuis,,LC,Glasser's disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; spleen; lung,involved in pathogenicity,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence,,,RP,25283960,PubMed,10.1016/j.micpath.2014.10.001,Microb Pathog. 2014 Dec;77C:17-23,jinbaowang@aliyun.com,Pathogen formerly called Haemophilus parasuis,J Yu 2014,2014,4 genes,Yu-2014-Identification of putative virulence-a,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4545,PHI:3320,UniProt,B8F3F8,GenBank,ACL31860,,,SH0165,ompP2,,,,,,,738,Glaesserella parasuis,,LC,Glasser's disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; spleen; lung,involved in pathogenicity,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence,,,RP,25283960,PubMed,10.1016/j.micpath.2014.10.001,Microb Pathog. 2014 Dec;77C:17-23,jinbaowang@aliyun.com,Pathogen formerly called Haemophilus parasuis,J Yu 2014,2014,4 genes,Yu-2014-Identification of putative virulence-a,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4546,PHI:3321,UniProt,Q5AJB1,GenBank,EAL02842,,,SC5314,Tfp1,,,,,,,5476,Candida albicans,,SN76,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,putative subunit of V-ATPase,,,,loss of pathogenicity,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene disruption; gene complementation,,,RP,25220074,PubMed,10.1016/j.fgb.2014.08.012,Fungal Genet Biol. 2014 Oct;71:58-67,nklimingchun@163.com,"The tfp1 D/Dmutant was sensitive to alkaline pH, elevated calcium concentrations, metal ions, and oxidative stress.",C Jia 2014,2014,1 gene,Jia-2014-Role of TFP1 in vacuolar acidificatio,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4547,PHI:3323,UniProt,Q4WT11,GenBank,EAL90421,,,Af293,sskB,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,MAP kinase kinase kinase of the HOG (high-osmolarity glycerol response) pathway,,,high-osmolarity glycerol response (HOG) signalling pathway,loss of pathogenicity,,,,,,,,reduced,,no,CaCl2; NaCl; MnCl2; paraquat; menadione; itraconazole; caspofungin,CaCl2: CHEBI:3312; NaCl: CHEBI:26710; MnCl2: CHEBI:63041; paraquat: CHEBI:34905; menadione: CHEBI:28869; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,RP,25196896,PubMed,10.1111/mmi.12785,Mol Microbiol. 2014 Nov;94(3):655-74,ggoldman@usp.br,"The deltasskBwas more sensitive to CaCl2, NaCl, and paraquat stress.",P A de Castro 2014,2014,1 gene,de Castro-2014-ChIP-seq reveals a role for Crz,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4548,PHI:3324,UniProt,Q0V687,GenBank,EAT91972,,,SN15,SN477,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Calingiri,,,leaf,synthesis of (R)-mellein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25326302,PubMed,10.1128/AEM.02745-14,Appl Environ Microbiol. 2014 Oct 17. pii: AEM.02745-14,yh.chooi@anu.edu.au,(R)-mellein inhibited the germination of wheat (Triticum aestivum) and barrel medic (Medicago truncatula) seeds at 200 µg/mL.,Y Chooi 2014,2014,1 gene,Chooi-2014-An In planta-Expressed Polyketide S,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4549,PHI:3325,UniProt,B5TQV9,GenBank,ACH87041,,,JJI51,PGM,,,,,,,1348,Streptococcus parauberis,,KSP20,streptococcosis,bony fishes,8255,Paralichthys olivaceus (related: japanese flounder),,,,kidney,phosphoglucomutase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,25240979,PubMed,10.1016/j.fsi.2014.09.012,Fish Shellfish Immunol. 2014 Dec;41(2):317-25,ily337@daum.net,,S H Woo 2014,2014,1 gene,Woo-2014-Effects of phosphoglucomutase gene (P,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4550,PHI:3328,UniProt,E9EMQ0,GenBank,XP_007817332,,,ARSEF 23,MrKu70,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,encoding a key component involved in nonhomologous end-joining DNA repair in fungi.,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,H2O2; KCl,H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,RP,25222118,PubMed,10.1371/journal.pone.0107657,PLoS One. 2014 Sep 15;9(9):e107657,wfang1@zju.edu.cn,"The deletion of MrKu70, a gene encoding a key component involved in nonhomologous end-joining DNA repair in fungi, dramatically increases the gene disruption efficiency.",C Xu 2014,2014,1 gene,Xu-2014-A high-throughput gene disruption meth,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4551,PHI:3329,UniProt,A7ESB3,GenBank,EDN92355,,,1980 UF-70,Ss-oah1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf,oxaloacetate acetylhydrolase,,,,reduced virulence,,yes,no,no,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25285668,PubMed,10.1111/mpp.12211,Mol Plant Pathol. 2014 Oct 6,rollinsj@ufl.edu,,X Liang 2014,2014,1 gene,Liang-2014-Oxaloacetate acetylhydrolase gene m,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4552,PHI:3329,UniProt,A7ESB3,GenBank,EDN92355,,,1980 UF-70,Ss-oah1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Bush Blue Lake 47,,,leaf,oxaloacetate acetylhydrolase,,,,reduced virulence,,yes,no,no,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25285668,PubMed,10.1111/mpp.12211,Mol Plant Pathol. 2014 Oct 6,rollinsj@ufl.edu,,X Liang 2014,2014,1 gene,Liang-2014-Oxaloacetate acetylhydrolase gene m,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4553,PHI:3329,UniProt,A7ESB3,GenBank,EDN92355,,,1980 UF-70,Ss-oah1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf,oxaloacetate acetylhydrolase,,,,reduced virulence,,yes,no,no,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25285668,PubMed,10.1111/mpp.12211,Mol Plant Pathol. 2014 Oct 6,rollinsj@ufl.edu,,X Liang 2014,2014,1 gene,Liang-2014-Oxaloacetate acetylhydrolase gene m,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4554,PHI:3329,UniProt,A7ESB3,GenBank,EDN92355,,,1980 UF-70,Ss-oah1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),,,,leaf,oxaloacetate acetylhydrolase,,,,reduced virulence,,yes,no,no,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25285668,PubMed,10.1111/mpp.12211,Mol Plant Pathol. 2014 Oct 6,rollinsj@ufl.edu,,X Liang 2014,2014,1 gene,Liang-2014-Oxaloacetate acetylhydrolase gene m,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4555,PHI:3329,UniProt,A7ESB3,GenBank,EDN92355,,,1980 UF-70,Ss-oah1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia,,,leaf,oxaloacetate acetylhydrolase,,,,reduced virulence,,yes,no,no,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25285668,PubMed,10.1111/mpp.12211,Mol Plant Pathol. 2014 Oct 6,rollinsj@ufl.edu,,X Liang 2014,2014,1 gene,Liang-2014-Oxaloacetate acetylhydrolase gene m,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4556,PHI:3329,UniProt,A7ESB3,GenBank,EDN92355,,,1980 UF-70,Ss-oah1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4232,Helianthus annuus (related: common sunflower),,,,leaf,oxaloacetate acetylhydrolase,,,,reduced virulence,,yes,no,no,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25285668,PubMed,10.1111/mpp.12211,Mol Plant Pathol. 2014 Oct 6,rollinsj@ufl.edu,,X Liang 2014,2014,1 gene,Liang-2014-Oxaloacetate acetylhydrolase gene m,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4557,PHI:3330,UniProt,P0CL88,GenBank,AAW44210,,,JEC21,Xrn1p,,,,,,,5207,Cryptococcus neoformans,,JEC33,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cytoplasmic exonuclease,,,,reduced virulence,yes,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,25267175,PubMed,10.1016/j.fgb.2014.09.007,Fungal Genet Biol. 2014 Sep 28;73C:20-28,janbon@pasteur.fr,,C Wollschlaeger 2014,2014,1 gene,Wollschlaeger-2014-Distinct and redundant role,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4558,PHI:3331,UniProt,J9VU41,GenBank,AFR97788,,,H99,snf7,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,vacuolar-sorting protein,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,25267175,PubMed,10.1016/j.fgb.2014.09.007,Fungal Genet Biol. 2014 Sep 28;73C:20-28,mhv@cbiot.ufrgs.br,,R M C Godinho 2014,2014,2 genes,Godinho-2014-The vacuolar-sorting protein Snf7,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4559,PHI:3332,UniProt,A0A095CFR8,GenBank,KGB78294,,,R265,snf7,,,,,,,552467,Cryptococcus bacillisporus,294750,R265,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,vacuolar-sorting protein,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,25267175,PubMed,10.1016/j.fgb.2014.09.007,Fungal Genet Biol. 2014 Sep 28;73C:20-28,mhv@cbiot.ufrgs.br,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,R M C Godinho 2014,2014,2 genes,Godinho-2014-The vacuolar-sorting protein Snf7,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4560,PHI:3333,UniProt,Q59UT5,GenBank,EAK94199,,,SC5314,pga7,,KC589pga7D::hisG/pga7D::hisG,,,,,5476,Candida albicans,,KC645,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,extracellular heme-binding proteins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,25275454,PubMed,10.1371/journal.ppat.1004407,PLoS Pathog. 2014 Oct 2;10(10):e1004407,danielk@tx.technion.ac.il,PGA7 deletion elicits a severe heme-iron utilization phenotype.,G Kuznets 2014,2014,1 gene,Kuznets-2014-A Relay Network of Extracellular,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4561,PHI:3334,UniProt,J9N8J0,BROAD,FOXG_11503,,,4287,con7-1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,leaf,transcription factor,,,,loss of pathogenicity,,,,yes (reduced),,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,25271883,PubMed,10.1094/MPMI-07-14-0205-R,Mol Plant Microbe Interact. 2014 Oct 1,ge2rurom@uco.es,"Targeted deletion of con7-1 produced non-pathogenic mutants with altered morphogenesis, including defects in cell wall structure, polar growth, hyphal branching and conidiation. By contrast, simultaneous inactivation of both con7-2 copies caused no detectable defects in the resulting mutants.",C Ruiz-Roldán 2014,2014,2 genes,Ruiz-Roldan-2014-The transcription factor Con7,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4562,PHI:3335,UniProt,J9NBD9,BROAD,FOXG_14029,,,4287,con7-2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,no,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,25271883,PubMed,10.1094/MPMI-07-14-0205-R,Mol Plant Microbe Interact. 2014 Oct 1,ge2rurom@uco.es,"Targeted deletion of con7-1 produced non-pathogenic mutants with altered morphogenesis, including defects in cell wall structure, polar growth, hyphal branching and conidiation. By contrast, simultaneous inactivation of both con7-2 copies caused no detectable defects in the resulting mutants.",C Ruiz-Roldán 2014,2014,2 genes,Ruiz-Roldan-2014-The transcription factor Con7,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4563,PHI:3336,UniProt,D4HX24,GenBank,CBA19715,,,CFBP1430,rpoS,,pGEMrpoS::Ω-Km,,,,,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,32224,Eriobotrya japonica (related: loquat),cv. Tanaka,,,fruit,regulation of stress and starvation response,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25331301,PubMed,10.1111/1574-6941.12444,FEMS Microbiol Ecol. 2014 Dec;90(3):895-907,elena.biosca@uv.es,"sigma factor RpoS regulates starvation and other stress responses. NCBI merged 'Eriobotrya japonica' Taxid '32224' into 'Rhaphiolepis bibas' Taxid '2843217', change made for PHI4.12 release. For PHI4.17 changed back to 'Eriobotrya japonica' Taxid '32224' following NCBI update.",R D Santander 2014,2014,1 gene,Santander-2014-Exploring new roles for the rpo,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4564,PHI:3336,UniProt,D4HX24,GenBank,CBA19715,,,CFBP1430,rpoS,,pGEMrpoS::Ω-Km,,,,,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Passe,,,fruit,regulation of stress and starvation response,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25331301,PubMed,10.1111/1574-6941.12444,FEMS Microbiol Ecol. 2014 Dec;90(3):895-907,elena.biosca@uv.es,sigma factor RpoS regulates starvation and other stress responses,R D Santander 2014,2014,1 gene,Santander-2014-Exploring new roles for the rpo,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4565,PHI:3337,UniProt,S5H6A1,GenBank,AGQ68292,,,CFSAN001921,sopB,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),glp-4,,,,virulence factors,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25312847,PubMed,10.1007/s10482-014-0300-7,Antonie Van Leeuwenhoek. 2014 Oct 14,ykcheah@medic.upm.edu.my,"There are significant phenotypic differences amongst strains carryingsopB,sopD andpipD gene mutations via the analysis of biochemical profiles of the bacteria. Interestingly, mutant strains displayed different susceptibility to chemical stressors from several distinct pharmacological and structural classes when compared to its isogenic parental strains.",C Khoo 2014,2014,6 genes,Khoo-2014-Pathogenicity and phenotypic analysi,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4566,PHI:3338,UniProt,H8LZT9,GenBank,AFD59840,,,798,sopD,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),glp-4,,,,virulence factors,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25312847,PubMed,10.1007/s10482-014-0300-7,Antonie Van Leeuwenhoek. 2014 Oct 14,ykcheah@medic.upm.edu.my,"There are significant phenotypic differences amongst strains carryingsopB,sopD andpipD gene mutations via the analysis of biochemical profiles of the bacteria. Interestingly, mutant strains displayed different susceptibility to chemical stressors from several distinct pharmacological and structural classes when compared to its isogenic parental strains.",C Khoo 2014,2014,6 genes,Khoo-2014-Pathogenicity and phenotypic analysi,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4567,PHI:3339,UniProt,H8LZ71,GenBank,AFD58044,,,798,pipD,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),glp-4,,,,virulence factors,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25312847,PubMed,10.1007/s10482-014-0300-7,Antonie Van Leeuwenhoek. 2014 Oct 14,ykcheah@medic.upm.edu.my,"There are significant phenotypic differences amongst strains carryingsopB,sopD andpipD gene mutations via the analysis of biochemical profiles of the bacteria. Interestingly, mutant strains displayed different susceptibility to chemical stressors from several distinct pharmacological and structural classes when compared to its isogenic parental strains.",C Khoo 2014,2014,6 genes,Khoo-2014-Pathogenicity and phenotypic analysi,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4568,PHI:3340,UniProt,V5RZP2,GenBank,AHB43717,,,24249,sopB,,,,,,,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,salmonellosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),glp-4,,,,virulence factors,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25312847,PubMed,10.1007/s10482-014-0300-7,Antonie Van Leeuwenhoek. 2014 Oct 14,ykcheah@medic.upm.edu.my,"There are significant phenotypic differences amongst strains carryingsopB,sopD andpipD gene mutations via the analysis of biochemical profiles of the bacteria. Interestingly, mutant strains displayed different susceptibility to chemical stressors from several distinct pharmacological and structural classes when compared to its isogenic parental strains.",C Khoo 2014,2014,6 genes,Khoo-2014-Pathogenicity and phenotypic analysi,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4569,PHI:3341,UniProt,V5RZH7,GenBank,AHB43652,,,24249,sopD,,,,,,,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,salmonellosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),glp-4,,,,virulence factors,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25312847,PubMed,10.1007/s10482-014-0300-7,Antonie Van Leeuwenhoek. 2014 Oct 14,ykcheah@medic.upm.edu.my,"There are significant phenotypic differences amongst strains carryingsopB,sopD andpipD gene mutations via the analysis of biochemical profiles of the bacteria. Interestingly, mutant strains displayed different susceptibility to chemical stressors from several distinct pharmacological and structural classes when compared to its isogenic parental strains.",C Khoo 2014,2014,6 genes,Khoo-2014-Pathogenicity and phenotypic analysi,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4570,PHI:3342,,no data found,,,,,,pipD,,,,,,,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,salmonellosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),glp-4,,,,virulence factors,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25312847,PubMed,10.1007/s10482-014-0300-7,Antonie Van Leeuwenhoek. 2014 Oct 14,ykcheah@medic.upm.edu.my,"There are significant phenotypic differences amongst strains carryingsopB,sopD andpipD gene mutations via the analysis of biochemical profiles of the bacteria. Interestingly, mutant strains displayed different susceptibility to chemical stressors from several distinct pharmacological and structural classes when compared to its isogenic parental strains.",C Khoo 2014,2014,6 genes,Khoo-2014-Pathogenicity and phenotypic analysi,Batch042B,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4571,PHI:3343,UniProt,B5SDM5,GenBank,KEI31823,,,NCPPB 909,nasA,,deltanasA::Gm (deletion construct containing the gentamicin (Gm) resistance cassette),,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf,assimilatory nitrate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24363343,PubMed,10.1128/JB.01378-13,J Bacteriol. 2014 Mar;196(5):949-60,cza@plantpath.wisc.edu,,B L Dalsing 2014,2014,1 gene,Dalsing-2014-Nitrate assimilation contributes,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4572,PHI:3344,UniProt,C1L2I8,GenBank,CAS05054,,,Clip80459,CodY,,,,prfA,UniProt: Q4TVQ0,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,metabolic regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25430920,PubMed,10.1111/mmi.12890,Mol Microbiol. 2014 Nov 27,anathe@post.tau.ac.il,,L Lobel 2014,2014,2 genes,Lobel-2014-The metabolic regulator CodY links,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4573,PHI:3345,UniProt,Q4TVQ0,GenBank,AAY54617,,,10403S,prfA,,,,CodY,UniProt: C1L2I8,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,virulence regulatory gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25430920,PubMed,10.1111/mmi.12890,Mol Microbiol. 2014 Nov 27,anathe@post.tau.ac.il,,L Lobel 2014,2014,2 genes,Lobel-2014-The metabolic regulator CodY links,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4574,PHI:3346,,no data found,GenBank,KM244526,,,AR628,sol5,,,,,,,5454,Ascochyta rabiei,,AR628,Ascochyta blight (chickpea),eudicots,3827,Cicer arietinum (related: chickpea),cv. Spanish White,,,leaf,Diels-Alderase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25372118,PubMed,10.1094/MPMI-08-14-0234-R,Mol Plant Microbe Interact. 2014 Nov 5,w-chen@wsu.edu,,W Kim 2014,2014,2 genes,Kim-2014-Functional Analyses of the Diels-Alde,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4575,PHI:3347,UniProt,D7UQ40,GenBank,BAJ09785,,,,sol5,,,,,,,48100,Alternaria solani,,ALS1; ALS2,early blight (potato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,Diels-Alderase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25372118,PubMed,10.1094/MPMI-08-14-0234-R,Mol Plant Microbe Interact. 2014 Nov 5,w-chen@wsu.edu,,W Kim 2014,2014,2 genes,Kim-2014-Functional Analyses of the Diels-Alde,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4576,PHI:3346,,no data found,GenBank,KM244526,,,AR628,sol5,,,,,,,5454,Ascochyta rabiei,,AR628,Ascochyta blight (chickpea),eudicots,3827,Cicer arietinum (related: chickpea),cv. Dwelley,,,leaf,Diels-Alderase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25372118,PubMed,10.1094/MPMI-08-14-0234-R,Mol Plant Microbe Interact. 2014 Nov 5,w-chen@wsu.edu,,W Kim 2014,2014,2 genes,Kim-2014-Functional Analyses of the Diels-Alde,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4577,PHI:3347,UniProt,D7UQ40,GenBank,BAJ09785,,,,sol5,,,,,,,48100,Alternaria solani,,ALS1; ALS2,early blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Russet Norkotah,,,leaf,Diels-Alderase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25372118,PubMed,10.1094/MPMI-08-14-0234-R,Mol Plant Microbe Interact. 2014 Nov 5,w-chen@wsu.edu,,W Kim 2014,2014,2 genes,Kim-2014-Functional Analyses of the Diels-Alde,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4578,PHI:3347,UniProt,D7UQ40,GenBank,BAJ09785,,,,sol5,,,,,,,48100,Alternaria solani,,ALS1; ALS2,early blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Ranger Russet,,,leaf,Diels-Alderase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25372118,PubMed,10.1094/MPMI-08-14-0234-R,Mol Plant Microbe Interact. 2014 Nov 5,w-chen@wsu.edu,,W Kim 2014,2014,2 genes,Kim-2014-Functional Analyses of the Diels-Alde,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4579,PHI:3348,UniProt,Q2FID9,GenBank,ABD20438,,,USA300_FPR3757,nfu,,nfu::tet; nfu::kan (strains were created by digesting the corresponding pJB38 plasmid with MluI and NheI and inserting the kan or tet genes between the up- and down-stream regions prior to mutant construction),,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Hsd:ND4,,,liver,aids in the maturation of iron-sulphur proteins,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25388433,PubMed,10.1111/mmi.12860,Mol Microbiol. 2014 Nov 12,jmboyd@AESOP.Rutgers.edu,A strain lacking Nfu is sensitive to exogenously supplied ROS and reactive nitrogen species.,A A Mashruwala 2014,2014,1 gene,Mashruwala-2014-Nfu facilitates the maturation,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4580,PHI:3349,UniProt,D7I613,GenBank,EFH97372,,,NCPPB 3335,bifA,,pGEM-T-bifAPsvAAL (pGEM-T easy derivate containing bifA gene from NCPPB 3335 with a pointmutation in the EAL motif (ApR)),,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,c-di-GMP phosphodiesterase,,,,reduced virulence,,,,,smaller knots than wild type,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25385023,PubMed,10.1111/mpp.12218,Mol Plant Pathol. 2014 Nov 11,crr@uma.es,The gene is also involved in motility.,I M Aragón 2014,2014,2 genes,Aragon-2014-The c-di-GMP phosphodiesterase Bif,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4581,PHI:3350,UniProt,Q882L6,GenBank,AAO56114,,,DC3000,bifA,,"pGEM-T-K.O bifAPsv- Km (pGEM-T derivate, containing 1.2 kb approx. on each side of the bifA gene from NCPPB 3335 interrupted by the kanamycin resistance gen nptII (ApR, KmR))",,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,c-di-GMP phosphodiesterase,,,,reduced virulence,,,,,smaller lesions and lesser chlorosis than wild type,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,25385023,PubMed,10.1111/mpp.12218,Mol Plant Pathol. 2014 Nov 11,crr@uma.es,The gene is also involved in motility.,I M Aragón 2014,2014,2 genes,Aragon-2014-The c-di-GMP phosphodiesterase Bif,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4582,PHI:3351,UniProt,I6Y0L1,GenBank,AFN50343,,,H37Rv,mbtE,,deltambtE::hyg,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10141,Cavia porcellus (related: domestic guinea pig),Duncan-Hartley,,,liver; lung; spleen,mycobactin biosynthesis,,,,reduced virulence,,,,,smaller lesions and lesser chlorosis than wild type,,,reduced; aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,23788726,PubMed,10.1093/infdis/jit250,J Infect Dis. 2013 Oct 15;208(8):1255-65,aniltyagi@south.du.ac.in,,P V Reddy 2013,2013,1 gene,Reddy-2013-Disruption of mycobactin biosynthes,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4583,PHI:3352,UniProt,E8VVE8,GenBank,ADV89163,,,MO6-24/O,prx3,,,,iscR,UniProt: Q7MNG3; GenBank: BAC93518,,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,Grx3/glutathione-dependent 1-Cys peroxiredoxin,,,,reduced virulence,,,,,smaller lesions and lesser chlorosis than wild type,,,,,no,H2O2; ONOO-,ONOO-: CHEBI:29330; H2O2: CHEBI:16240,,,,,gene mutation: characterised; gene complementation,,,RP,25398878,PubMed,10.1074/jbc.M114.611020,J Biol Chem. 2014 Nov 14. pii: jbc.M114.611020,choish@snu.ac.kr,The prx3 mutation impaired growth in the medium containing peroxides.,J G Lim 2014,2014,1 gene,Lim-2014-Characterization of the Vibrio vulnif,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4584,PHI:3353,UniProt,G5ADB3,GenBank,EGZ06166,,,P6497,PsPSR2,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,root,RxLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,Agrobacterium rhizogenes K599 carrying pEG104 or pEG101::PsPSR2,,RP,25387135,PubMed,10.1094/MPMI-06-14-0190-R,Mol Plant Microbe Interact. 2014 Dec;27(12):1379-89,wangyc@njau.edu.cn,,Q Xiong 2014,2014,1 gene,Xiong-2014-Phytophthora Suppressor of RNA Sile,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4585,PHI:3354,UniProt,A0A023NA98,GenBank,AHW45240,,,BAA87,rtxA1,,,,,,,672,Vibrio vulnificus,216895,CMCP6,vibriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,production of MARTX toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24614656,PubMed,10.1128/IAI.00017-14,Infect Immun. 2014 May;82(5):2148-57,k-satchell@northwestern.edu,,K J Ziolo 2014,2014,1 gene,Ziolo-2014-Vibrio vulnificus Biotype 3 MARTX t,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4586,PHI:3355,UniProt,W7LTW0,GenBank,EWG38880,,,7600,Mads1,,deltamads1::HPH; deltamads1::GEN,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. B73,,,kernel; stem,MADS-box transcription factor,,,,unaffected pathogenicity,yes,,,,,wild type,reduced,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,23985144,PubMed,10.1099/mic.0.068775-0,Microbiology. 2013 Nov;159(Pt 11):2259-68,wbshim@tamu.edu,,C S 2013,2013,2 genes,Ortiz-2013-The role of MADS-box transcription,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4587,PHI:3356,UniProt,W7M2E5,GenBank,EWG41694,,,7600,Mads2,,deltamads2::HPH; deltamads2::GEN,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. B73,,,kernel; stem,MADS-box transcription factor,,,,unaffected pathogenicity,yes,,,,,wild type,reduced,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,23985144,PubMed,10.1099/mic.0.068775-0,Microbiology. 2013 Nov;159(Pt 11):2259-68,wbshim@tamu.edu,,C S 2013,2013,2 genes,Ortiz-2013-The role of MADS-box transcription,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4588,PHI:3355,UniProt,W7LTW0,GenBank,EWG38880,,,7600,Mads1,,deltamads1::HPH; deltamads1::GEN,,,,,117187,Fusarium verticillioides,,7598,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. B73,,,kernel; stem,MADS-box transcription factor,,,,unaffected pathogenicity,yes,,,,,wild type,reduced,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,23985144,PubMed,10.1099/mic.0.068775-0,Microbiology. 2013 Nov;159(Pt 11):2259-68,wbshim@tamu.edu,,C S 2013,2013,2 genes,Ortiz-2013-The role of MADS-box transcription,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4589,PHI:3356,UniProt,W7M2E5,GenBank,EWG41694,,,7600,Mads2,,deltamads2::HPH; deltamads2::GEN,,,,,117187,Fusarium verticillioides,,7598,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. B73,,,kernel; stem,MADS-box transcription factor,,,,unaffected pathogenicity,yes,,,,,wild type,reduced,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,23985144,PubMed,10.1099/mic.0.068775-0,Microbiology. 2013 Nov;159(Pt 11):2259-68,wbshim@tamu.edu,,C S 2013,2013,2 genes,Ortiz-2013-The role of MADS-box transcription,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4590,PHI:3357,UniProt,F8KKE5,GenBank,CCB52909,,,N920143,srtA,,,,,,,28035,Staphylococcus lugdunensis,1034809,N920143,infective endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,blood; kidney; heart,infection process,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,23943787,PubMed,10.1099/mic.0.070292-0,Microbiology. 2013 Oct;159(Pt 10):2141-52,tfoster@tcd.ie,,S Heilbronner 2013,2013,1 gene,Heilbronner-2013-Sortase A promotes virulence,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4591,PHI:3358,UniProt,A0Q5Y3,GenBank,ABK89648,,,U112,Cas9,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),,,,spleen,replicate and survive during murine infection.,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24256228,PubMed,10.1042/BST20130163,Biochem Soc Trans. 2013 Dec;41(6):1407-11,david.weiss@emory.edu,"Cas9 represses the expression of a BLP (bacterial lipoprotein) that could otherwise be recognized by TLR2 (Toll-like receptor 2), a host protein involved in initiating an antibacterial pro-inflammatory response.",T R Sampson 2013,2013,1 gene,Sampson-2013-Cas9-dependent endogenous gene re,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4592,PHI:3359,,no data found,,,,,,CPS,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,production of gibberellin plant hormones.,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25406717,PubMed,10.1111/nph.13187,New Phytol. 2014 Nov 18,rjpeters@iastate.edu,,X Lu 2014,2014,3 genes,Lu-2014-An ent-kaurene-derived diterpenoid vir,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4593,PHI:3360,UniProt,G7TIP2,GenBank,AEQ94335,,,BLS256,KS,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,production of gibberellin plant hormones.,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25406717,PubMed,10.1111/nph.13187,New Phytol. 2014 Nov 18,rjpeters@iastate.edu,,X Lu 2014,2014,3 genes,Lu-2014-An ent-kaurene-derived diterpenoid vir,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4594,PHI:3361,,no data found,,,,,,CYP112,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,production of gibberellin plant hormones.,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25406717,PubMed,10.1111/nph.13187,New Phytol. 2014 Nov 18,rjpeters@iastate.edu,,X Lu 2014,2014,3 genes,Lu-2014-An ent-kaurene-derived diterpenoid vir,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4595,PHI:3362,UniProt,Q4WIN1,GenBank,EAL87224,,,Af293,SrbA,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,regulator of the fungal hypoxia response,,,,reduced virulence,,,,,,,,,,no,voriconazole,voriconazole: CHEBI:10023,,,,,gene deletion: full; gene complementation,,,RP,25375670,PubMed,10.1371/journal.ppat.1004576,PLoS Pathog. 2014 Nov 24;10(11):e1004576,Robert.A.Cramer.Jr@Dartmouth.edu,,D Chung 2014,2014,2 genes,Chung-2014-ChIP-seq and In Vivo Transcriptome,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4596,PHI:3363,UniProt,B0YEL4,GenBank,EDP47358,,,A1163,SrbB,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,regulator of the fungal hypoxia response,,,,reduced virulence,,,,,,,,,,no,voriconazole,voriconazole: CHEBI:10023,,,,,gene deletion: full; gene complementation,,,RP,25375670,PubMed,10.1371/journal.ppat.1004576,PLoS Pathog. 2014 Nov 24;10(11):e1004576,Robert.A.Cramer.Jr@Dartmouth.edu,,D Chung 2014,2014,2 genes,Chung-2014-ChIP-seq and In Vivo Transcriptome,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4597,PHI:3362,UniProt,Q4WIN1,GenBank,EAL87224,,,Af293,SrbA,,,,,,PHI:3363,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,regulator of the fungal hypoxia response,,,,reduced virulence,,,,,,,,reduced,,no,voriconazole,voriconazole: CHEBI:10023,,,,,gene deletion: full; gene complementation,,,RP,25375670,PubMed,10.1371/journal.ppat.1004576,PLoS Pathog. 2014 Nov 24;10(11):e1004576,Robert.A.Cramer.Jr@Dartmouth.edu,,D Chung 2014,2014,2 genes,Chung-2014-ChIP-seq and In Vivo Transcriptome,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4598,PHI:3363,UniProt,B0YEL4,GenBank,EDP47358,,,A1163,SrbB,,,,,,PHI:3362,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,regulator of the fungal hypoxia response,,,,reduced virulence,,,,,,,,reduced,,no,voriconazole,voriconazole: CHEBI:10023,,,,,gene deletion: full; gene complementation,,,RP,25375670,PubMed,10.1371/journal.ppat.1004576,PLoS Pathog. 2014 Nov 24;10(11):e1004576,Robert.A.Cramer.Jr@Dartmouth.edu,,D Chung 2014,2014,2 genes,Chung-2014-ChIP-seq and In Vivo Transcriptome,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4599,PHI:3364,UniProt,B2HHI1,GenBank,ACC40113,,,M,MMAR_1663,,1663::Tn::1664 (M strain bearing a transposon insertion between the MMAR_1663and MMAR_1664 genes),,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,locus required for ESX-1 export,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24610712,PubMed,10.1128/JB.01502-14,J Bacteriol. 2014 May;196(10):1877-88,pchampio@nd.edu,,G M Kennedy 2014,2014,2 genes,Kennedy-2014-A novel ESX-1 locus reveals that,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4600,PHI:3365,UniProt,B2HHI2,GenBank,ACC40114,,,M,MMAR_1664,,1663::Tn::1664 (M strain bearing a transposon insertion between the MMAR_1663and MMAR_1664 genes),,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,locus required for ESX-1 export,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24610712,PubMed,10.1128/JB.01502-14,J Bacteriol. 2014 May;196(10):1877-88,pchampio@nd.edu,,G M Kennedy 2014,2014,2 genes,Kennedy-2014-A novel ESX-1 locus reveals that,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4601,PHI:3366,UniProt,Q99VU9,GenBank,BAB56834,,,Mu50,CcpE,,pCL::ccpE,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver,catabolite control protein,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25368190,PubMed,10.1073/pnas.1411077111,Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):E4981-90,yangcg@simm.ac.cn,"Inactivation of CcpE results in increased staphyloxanthin production, improved ability to acquire iron, increased resistance to whole-blood-mediated killing, and enhanced bacterial virulence in a mouse model of systemic infection.",Y Ding 2014,2014,1 gene,Ding-2014-Metabolic sensor governing bacterial,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4602,PHI:3367,UniProt,A9R9G8,GenBank,ABX88786,,,Angola,yopM,,,,,,,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6NHsd,,,liver,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372388,PubMed,10.1371/journal.pone.0110956,PLoS One. 2014 Nov 5;9(11):e110956,scstra01@uky.edu,"In mice that lacked the apoptosis mediator caspase-3 the infection dynamics were novel: the parent Y. pestis was limited in growth comparably to the deltayopM-1 strain in liver, and in spleen a partial growth limitation for parent Y. pestis was seen.",Z Ye 2014,2014,2 genes,Ye-2014-Caspase-3 Mediates the Pathogenic Effe,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4603,PHI:3369,UniProt,Q59RL4,GenBank,EAK93117,,,SC5314,stv1,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,V0 subunit a gene,,,secretory pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,23884420,PubMed,10.1074/jbc.M113.494815,J Biol Chem. 2013 Sep 6;288(36):26256-64,rrao@jhmi.edu,,C Patenaude 2013,2013,2 genes,Patenaude-2013-Essential role for vacuolar aci,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4604,PHI:3370,UniProt,C4YGV6,GenBank,EEQ44988,,,WO-1,vph1,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,acidification of the vacuole,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,23884420,PubMed,10.1074/jbc.M113.494815,J Biol Chem. 2013 Sep 6;288(36):26256-64,rrao@jhmi.edu,,C Patenaude 2013,2013,2 genes,Patenaude-2013-Essential role for vacuolar aci,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4605,PHI:3371,UniProt,L3EHG5,GenBank,ELD24912,,,KTE210,DotU,,DE719deltadotU (dotUdeletion mutant in DE719),,,,,562,Escherichia coli,,DE719,systemic infection,birds,8839,Anas platyrhynchos (related: mallard),,,,,component organelle trafficking protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25426107,PubMed,10.3389/fmicb.2014.00588,Front Microbiol. 2014 Nov 7;5:588,yus@shvri.ac.cn,,S Wang 2014,2014,1 gene,Wang-2014-DotU expression is highly induced du,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4606,PHI:3372,UniProt,P11437,GenBank,AAA25725,,,,pPg6L3,,pPg6L3::Tn5-1 (Tn5 insertional mutagenesis cosmid clone,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial blight (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,16593517,PubMed,10.1073/pnas.81.19.6024,Proc Natl Acad Sci U S A. 1984 Oct;81(19):6024-8,,,B J STASKAWICZ 1984,1984,1 gene,Staskawicz-1984-Cloned avirulence gene of Pseu,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4607,PHI:3372,UniProt,P11437,GenBank,AAA25725,,,,pPg6L3,,pPg6L3::Tn5-1 (Tn5 insertional mutagenesis cosmid clone,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial blight (soybean),eudicots,3847,Glycine max (related: soybean),cv. Peking,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,16593517,PubMed,10.1073/pnas.81.19.6024,Proc Natl Acad Sci U S A. 1984 Oct;81(19):6024-8,,,B J STASKAWICZ 1984,1984,1 gene,Staskawicz-1984-Cloned avirulence gene of Pseu,Batch043,2014-12-01,MC,,,,,,,,,,,,,
,,Record 4608,PHI:3373,UniProt,I1RYI2,GenBank,ESU16014,,,PH-1,FgSho1,chromosome 4,,,FgSte50-Ste11-Ste7,"FgSte50, UniProt: I1RJR9; FgSte11, UniProt: V6RAJ2; FgSte7, UniProt: I1RZQ2",,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,fungal development and pathogenicity,,,mitogen-activated protein kinase (MAPK) signaling pathway,reduced virulence,,,yes,,,reduced,,reduced,wild type,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25388878,PubMed,10.1111/nph.13158,New Phytol. 2014 Nov 12,zhma@zju.edu.cn,,Q Gu 2014,2014,5 genes,Gu-2014-The transmembrane protein FgSho1 regul,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4609,PHI:3374,UniProt,I1S028,GenBank,ESU16707,,,PH-1,FgSln1,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,fungal development and pathogenicity,,,mitogen-activated protein kinase (MAPK) signaling pathway,reduced virulence,,,yes,,,reduced,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25388878,PubMed,10.1111/nph.13158,New Phytol. 2014 Nov 12,zhma@zju.edu.cn,,Q Gu 2014,2014,5 genes,Gu-2014-The transmembrane protein FgSho1 regul,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4610,PHI:3375,UniProt,I1RJR9,GenBank,ESU09037,,,PH-1,FgSte50,chromosome 2,,,FgSho1,UniProt: I1RYI2,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,fungal development and pathogenicity,,,mitogen-activated protein kinase (MAPK) signaling pathway,loss of pathogenicity,,,yes,,,reduced,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25388878,PubMed,10.1111/nph.13158,New Phytol. 2014 Nov 12,zhma@zju.edu.cn,,Q Gu 2014,2014,5 genes,Gu-2014-The transmembrane protein FgSho1 regul,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4611,PHI:3376,UniProt,A0A0E0SIZ6,EMBL,FGRAMPH1_01T18031,,,PH-1,FgSte11,chromosome 3,,,FgSho1,UniProt: I1RYI2,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,fungal development and pathogenicity,,,mitogen-activated protein kinase (MAPK) signaling pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25388878,PubMed,10.1111/nph.13158,New Phytol. 2014 Nov 12,zhma@zju.edu.cn,,Q Gu 2014,2014,5 genes,Gu-2014-The transmembrane protein FgSho1 regul,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4612,PHI:3377,UniProt,I1RZQ2,GenBank,ESU16547,,,PH-1,FgSte7,chromosome 1,,,FgSho1,UniProt: I1RYI2,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,fungal development and pathogenicity,,,mitogen-activated protein kinase (MAPK) signaling pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25388878,PubMed,10.1111/nph.13158,New Phytol. 2014 Nov 12,zhma@zju.edu.cn,,Q Gu 2014,2014,5 genes,Gu-2014-The transmembrane protein FgSho1 regul,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4613,PHI:3378,UniProt,G9JLA8,GenBank,JN870922,,,ISPaVe ER 1211,Plegl1,,,,,,,285811,Pseudopyrenochaeta lycopersici,,ISPaVe ER 1211,corky root rot (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Corbarino,,,root,lytic polysaccharide monooxygenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25413737,PubMed,10.1007/s00294-014-0461-y,Curr Genet. 2014 Nov 21,maria.aragona@entecra.it,Pathogen formerly called Pyrenochaeta lycopersici,M Aragona 2014,2014,1 gene,Aragona-2014-Genetic transformation of the tom,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4614,PHI:3379,,no data found,,,,,,PsSRPKL,,BSMV:PsSRPKL-1as or BSMV:PsSRPKL-2as,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,pathogenesis,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,RP,25407954,PubMed,10.1111/1462-2920.12719,Environ Microbiol. 2014 Nov 19,kangzs@nwsuaf.edu.cn,PsSRPKL may be involved in overcoming plant defense responses adn oxidative stress responses.,Y Cheng 2014,2014,1 gene,Cheng-2014-Characterization of Protein Kinase,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4615,PHI:3380,UniProt,W7MT41,GenBank,EWG54281,,,7600,FVEG_12534,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4616,PHI:3381,UniProt,W7N2B4,GenBank,EWG54279,,,7600,FVEG_12533,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affect virulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4617,PHI:3382,UniProt,W7MS18,GenBank,EWG54278,,,7600,FVEG_12532,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4618,PHI:3383,UniProt,W7N2A8,GenBank,EWG54275,,,7600,FVEG_12531,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4619,PHI:3384,UniProt,W7N2C1,GenBank,EWG54274,,,7600,FVEG_12530,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4620,PHI:3385,UniProt,W7MS09,GenBank,EWG54273,,,7600,FVEG_12529,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4621,PHI:3386,UniProt,W7NCN7,GenBank,EWG54272,,,7600,FVEG_12528,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4622,PHI:3387,UniProt,W7MT31,GenBank,EWG54266,,,7600,FVEG_12523,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4623,PHI:3388,UniProt,W7N2B2,GenBank,EWG54264,,,7600,FVEG_12522,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4624,PHI:3389,UniProt,W7MS01,GenBank,EWG54263,,,7600,FVEG_12521,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4625,PHI:3390,UniProt,W7MT28,GenBank,EWG54261,,,7600,FVEG_12520,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4626,PHI:3391,UniProt,W7N293,GenBank,EWG54260,,,7600,FVEG_12519,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize); stalk rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4627,PHI:3392,UniProt,J9NJ73,,,,,4287,FOXG 15248,chromosome 5,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4628,PHI:3393,,no data found,,,,,,FUB2,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4629,PHI:3394,UniProt,J9NJ72,,,,,4287,FOXG 15247,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4630,PHI:3395,UniProt,J9NJ69,,,,,4287,FOXG 15244,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4631,PHI:3396,UniProt,J9NJ68,,,,,4287,FOXG 15243,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4632,PHI:3397,UniProt,J9NJ66,,,,,,FOXG 15241,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4633,PHI:3398,UniProt,J9NJ65,,,,,4287,FOXG 15240,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4634,PHI:3399,UniProt,J9NJ64,,,,,4287,FOXG 15239,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4635,PHI:3400,UniProt,J9NJ63,,,,,4287,FOXG 15238,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4636,PHI:3401,UniProt,J9NJ62,,,,,4287,FOXG 15237,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4637,PHI:3402,UniProt,J9NJ61,,,,,4287,FOXG 15236,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4638,PHI:3403,UniProt,J9NJ60,,,,,4287,FOXG 15235,,,,,,,5507,Fusarium oxysporum,,Foxy20,Fusarium wilt,eudicots,336126,Selenicereus trigonus (related: strawberry-pear),,,,shoot,fusaric acid biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25372119,PubMed,10.1094/MPMI-09-14-0264-R,Mol Plant Microbe Interact. 2014 Nov 5,tessyl1@korea.kr,"Although the ability to produce fusaric acid contributed to the phytotoxicity of F. oxysporum culture extracts, lack of production did not affectvirulence of F. oxysporum on cactus or F. verticillioides on maize seedlings.",D W Brown 2014,2014,24 genes,Brown-2014-Identification of a 12-gene fusaric,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4639,PHI:3404,UniProt,Q9F286,GenBank,AE013962_2,,,KIM,yapG,,"pMWO : :yapGSDM1+2+3+4+5 (pMWO : :yapGcontaining K512A, KR548-549AG, K558A, KR594-595AG and K604A mutations)",,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; lung; lymph node,proteolytic processing,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23657527,PubMed,10.1099/jmm.0.056275-0,J Med Microbiol. 2013 Aug;62(Pt 8):1124-34,vlmiller@med.unc.edu,YapG does not contribute toY. pestisvirulence in established mouse models of bubonic and pneumonic infection.,M C Lane 2013,2013,1 gene,Lane-2013-Proteolytic processing of the Yersin,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4640,PHI:3405,UniProt,W8DUB2-W8DW48,,,,,LMG 2665,T6SS-1,,,,,,,553,Pantoea ananatis,1378093,LMG 2665,,monocots,4679,Allium cepa (related: onion),cv. Texas Grano,,,leaf,virulence mechanism,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25411959,PubMed,10.1094/MPMI-07-14-0219-R,Mol Plant Microbe Interact. 2014 Nov 20,Teresa.Coutinho@up.ac.za,"please note that multiple gene regions were disrupted T6SS-1 (N454_00602to N454_00638), T6SS-3 (N454_0002 13 to N454_0008)",D Y Shyntum 2014,2014,4 genes,Shyntum-2014-Pantoea ananatis utilizes a type,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4641,PHI:3406,UniProt,W8DUB2-W8DW13,,,,,LMG 2665,T6SS-3,,,,,,,553,Pantoea ananatis,1378093,LMG 2665,,monocots,4679,Allium cepa (related: onion),cv. Texas Grano,,,leaf,virulence mechanism,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25411959,PubMed,10.1094/MPMI-07-14-0219-R,Mol Plant Microbe Interact. 2014 Nov 20,Teresa.Coutinho@up.ac.za,"please note that multiple gene regions were disrupted T6SS-1 (N454_00602to N454_00638), T6SS-3 (N454_0002 13 to N454_0008)",D Y Shyntum 2014,2014,4 genes,Shyntum-2014-Pantoea ananatis utilizes a type,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4642,PHI:3407,UniProt,W8DUB8,,,,,LMG 2665,TssA,,,,,,,553,Pantoea ananatis,1378093,LMG 2665,,monocots,4679,Allium cepa (related: onion),cv. Texas Grano,,,leaf,virulence mechanism,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25411959,PubMed,10.1094/MPMI-07-14-0219-R,Mol Plant Microbe Interact. 2014 Nov 20,Teresa.Coutinho@up.ac.za,,D Y Shyntum 2014,2014,4 genes,Shyntum-2014-Pantoea ananatis utilizes a type,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4643,PHI:3408,UniProt,W8DVN3,,,,,LMG 2665,TssD,,,,,,,553,Pantoea ananatis,1378093,LMG 2665,,monocots,4679,Allium cepa (related: onion),cv. Texas Grano,,,leaf,virulence mechanism,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25411959,PubMed,10.1094/MPMI-07-14-0219-R,Mol Plant Microbe Interact. 2014 Nov 20,Teresa.Coutinho@up.ac.za,,D Y Shyntum 2014,2014,4 genes,Shyntum-2014-Pantoea ananatis utilizes a type,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4644,PHI:3409,UniProt,Q9I0P4,GenBank,AE004688_3,,,PAO1,qteE,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1-UW,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,quorum sensing,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25420086,PubMed,10.1371/journal.pone.0112105,PLoS One. 2014 Nov 24;9(11):e112105,livia.leoni@uniroma3.it,,R Bondı 2014,2014,2 genes,Bondi-2014-Affecting Pseudomonas aeruginosa Ph,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4645,PHI:3410,UniProt,Q9X7H4,GenBank,AAD22496,,,PAO1,rsaL,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1-UW,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,quorum sensing,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25420086,PubMed,10.1371/journal.pone.0112105,PLoS One. 2014 Nov 24;9(11):e112105,livia.leoni@uniroma3.it,,R Bondı 2014,2014,2 genes,Bondi-2014-Affecting Pseudomonas aeruginosa Ph,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4646,PHI:3411,UniProt,O68539,GenBank,AAC38612,,,,bscN,,,,,,,518,Bordetella bronchiseptica,1427985,KM22,infectious bronchitis,even-toed ungulates,9823,Sus scrofa (related: pig),,,,respiratory system,required for maximal disease severity and persistence in the swine lower respiratory tract,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24366249,PubMed,10.1128/IAI.01115-13,Infect Immun. 2014 Mar;82(3):1092-103,tracy.nicholson@ars.usda.gov,"Bordetella T3SS is required for maximal persistence and disease severity in pigs, but not for transmission.",T L Nicholson 2014,2014,1 gene,Nicholson-2014-The Bordetella bronchiseptica t,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4647,PHI:3412,UniProt,Q8PM59,GenBank,AAM36442,,,306,pstB,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,leaf,phosphate metabolism,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25403594,PubMed,10.1007/s10142-014-0414-z,Funct Integr Genomics. 2014 Nov 18,marcia@iq.ufrj.br,,L M Moreira 2014,2014,1 gene,Moreira-2014-Chemotactic signal transduction a,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4648,PHI:3412,UniProt,Q8PM59,GenBank,AAM36442,,,306,pstB,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,171249,Citrus limonia (related: mandarin lime),,,,leaf,phosphate metabolism,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25403594,PubMed,10.1007/s10142-014-0414-z,Funct Integr Genomics. 2014 Nov 18,marcia@iq.ufrj.br,,L M Moreira 2014,2014,1 gene,Moreira-2014-Chemotactic signal transduction a,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4649,PHI:3413,UniProt,A4SUE7,GenBank,ABO92519,,,A449,Ati2,,,,,,,645,Aeromonas salmonicida,382245,A449,furunculosis,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba)(non-host bioassay),,,,,TTSS effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,23832001,PubMed,10.1099/mic.0.067959-0,Microbiology. 2013 Sep;159(Pt 9):1937-45,steve.charette@bcm.ulaval.ca,,S Dallaire-Dufresne 2013,2013,1 gene,Dallaire-Dufres-2013-Aeromonas salmonicida Ati,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4650,PHI:3414,,no data found,,VIBAEv3_A30043,,,,varS,,,,,,,28171,Vibrio aestuarianus,,07_115,,bivalves,29159,Crassostrea gigas (related: pacific oyster),,,,,codes for a signal transduction histidine-protein kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25384557,PubMed,10.1111/1462-2920.12699,Environ Microbiol. 2014 Nov 11,frederique.le-roux@sb-roscoff.fr,,D Goudenège 2014,2014,1 gene,Goudenege-2014-A single regulatory gene is suf,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4651,PHI:3415,UniProt,T2BNJ5,GenBank,AGV14291,,,H99,Fre2,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,ferric reductases,,,,reduced virulence,,,,,,,,reduced,,no,fluconazole; miconazole; amphotericin B,"fluconazole: CHEBI:46081, CAS:86386-73-4; miconazole: CHEBI:6923; amphotericin B: CHEBI:2682",,,,,gene deletion: full; gene complementation,,,RP,24478097,PubMed,10.1128/IAI.01357-13,Infect Immun. 2014 Feb;82(2):839-50,kronstad@msl.ubc.ca,"mutants showed reduced growth on hemin and transferrin. / None of the deletion strains showed altered susceptibility to the polyene antifungal drug amphotericin B (Fig. 8A). However, thefre4 strain showed increased susceptibility to the azole antifungal drugs fluconazole and miconazole.",S Saikia 2014,2014,2 genes,Saikia-2014-Role of ferric reductases in iron,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4652,PHI:3416,UniProt,J9VKZ2,GenBank,AFR92350,,,H99,Fre4,,,,,,PHI:3415,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,ferric reductases,,,,reduced virulence,,,,,,,,reduced,,no,fluconazole; miconazole; amphotericin B,"fluconazole: CHEBI:46081, CAS:86386-73-4; miconazole: CHEBI:6923; amphotericin B: CHEBI:2682",,,,,gene deletion: full; gene complementation,,,RP,24478097,PubMed,10.1128/IAI.01357-13,Infect Immun. 2014 Feb;82(2):839-50,kronstad@msl.ubc.ca,"mutants showed reduced growth on hemin and transferrin. / None of the deletion strains showed altered susceptibility to the polyene antifungal drug amphotericin B (Fig. 8A). However, thefre4 strain showed increased susceptibility to the azole antifungal drugs fluconazole and miconazole.",S Saikia 2014,2014,2 genes,Saikia-2014-Role of ferric reductases in iron,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4653,PHI:3415,UniProt,T2BNJ5,GenBank,AGV14291,,,H99,Fre2,,,,,,PHI:3416,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,ferric reductases,,,,reduced virulence,,,,,,,,reduced,,no,fluconazole; miconazole; amphotericin B,"fluconazole: CHEBI:46081, CAS:86386-73-4; miconazole: CHEBI:6923; amphotericin B: CHEBI:2682",,,,,gene deletion: full; gene complementation,,,RP,24478097,PubMed,10.1128/IAI.01357-13,Infect Immun. 2014 Feb;82(2):839-50,kronstad@msl.ubc.ca,"mutants showed reduced growth on hemin and transferrin. / None of the deletion strains showed altered susceptibility to the polyene antifungal drug amphotericin B (Fig. 8A). However, thefre4 strain showed increased susceptibility to the azole antifungal drugs fluconazole and miconazole.",S Saikia 2014,2014,2 genes,Saikia-2014-Role of ferric reductases in iron,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4654,PHI:3417,UniProt,W5ZQ93,GenBank,AHI43604,,,,Ohmm,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mitochondrial transmembrane protein,,,Hog1 MAP kinase,increased virulence (hypervirulence),,,,,,reduced; aberrant,,wild type,increased,no,sorbitol; NaCl; H2O2; menadione,H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; menadione: CHEBI:28869,,,,,gene disruption; gene complementation,,,RP,25403093,PubMed,10.1111/1462-2920.12713,Environ Microbiol. 2014 Nov 18,yjzhang@swu.edu.cn,,Z He 2014,2014,1 gene,He-2014-A novel mitochondrial membrane protein,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4655,PHI:3418,UniProt,Q5DPX0,GenBank,Q5DPX0_STASA,,,,ssp,,deltassp::ermB (ssp gene is interrupted by an ermB resistance gene),,,,,29385,Staphylococcus saprophyticus,,9325,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,lipase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23959029,PubMed,10.4161/viru.25875,Virulence. 2013 Oct 1;4(7):604-11,Florian.Szabados@rub.de,,F Szabados 2013,2013,1 gene,Szabados-2013-Staphylococcus saprophyticus sur,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4656,PHI:3418,UniProt,Q5DPX0,GenBank,Q5DPX0_STASA,,,,ssp,,deltassp::ermB (ssp gene is interrupted by an ermB resistance gene),,,,,29385,Staphylococcus saprophyticus,,7108,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,lipase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23959029,PubMed,10.4161/viru.25875,Virulence. 2013 Oct 1;4(7):604-11,Florian.Szabados@rub.de,,F Szabados 2013,2013,1 gene,Szabados-2013-Staphylococcus saprophyticus sur,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4657,PHI:3419,UniProt,Q8XT88,GenBank,CAD17378,,,GMI1000,fcs,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,stem; root,feruloyl-CoA synthetase involved in HCA degradation,,,HCA degradation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25423265,PubMed,10.1094/MPMI-09-14-0292-FI,Mol Plant Microbe Interact. 2014 Nov 25,cza@plantpath.wisc.edu,,T M Lowe 2014,2014,1 gene,"Lowe-2014-Hydroxycinnamic acid degradation, a",Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4658,PHI:3420,UniProt,Q63K61,GenBank,CAH38977,,,K96243,BPSS1504,,"BpdeltaBPSS1504 (E8 derivate,BPSS1504ORF deleted)",,,,,28450,Burkholderia pseudomallei,,E8,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; liver,involved in the integrity of the T6SS1 apparatus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24595140,PubMed,10.1128/IAI.01544-14,Infect Immun. 2014 May;82(5):2006-15,katrin.breitbach@uni-greifswald.de,,V Hopf 2014,2014,1 gene,"Hopf-2014-BPSS1504, a cluster 1 type VI secret",Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4659,PHI:3421,,no data found,GenBank,KJ756328,,,Th120,momL,,,,,,,552546,Flagellimonas olearia,,Th120,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,N-acyl homoserine lactonase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25398866,PubMed,10.1128/AEM.02805-14,Appl Environ Microbiol. 2015 Jan 15;81(2):774-82,xhzhang@ouc.edu.cn,pathogen species name changed in PHI4.17 from 'Muricauda olearia' to 'Flagellimonas olearia'.,K Tang 2014,2014,1 gene,"Tang-2014-MomL, a novel marine-derived N-acyl",Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4660,PHI:3422,,no data found,,,,,,Pfv80,,"80:: pKNOCK mutant of PfvUPB0736; Nfr,Kmr",,,,,50340,Pseudomonas fuscovaginae,1150862,UPB0736,sheath brown rot,eudicots,63459,Chenopodium quinoa (related: quinoa),,,,leaf,involved in virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25394860,PubMed,10.1186/s12866-014-0274-7,BMC Microbiol. 2014 Nov 14;14(1):274,venturi@icgeb.org,,H K Patel 2014,2014,9 genes,Patel-2014-Identification of virulence associa,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4661,PHI:3423,,no data found,,,,,,Pfv90,,"90:: pKNOCK mutant of PfvUPB0736; Nfr,Kmr",,,,,50340,Pseudomonas fuscovaginae,1150862,UPB0736,sheath brown rot,eudicots,63459,Chenopodium quinoa (related: quinoa),,,,leaf,involved in virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25394860,PubMed,10.1186/s12866-014-0274-7,BMC Microbiol. 2014 Nov 14;14(1):274,venturi@icgeb.org,,H K Patel 2014,2014,9 genes,Patel-2014-Identification of virulence associa,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4662,PHI:3424,,no data found,,,,,,Pfv188,,"188:: pKNOCK mutant of PfvUPB0736; Nfr,Kmr",,,,,50340,Pseudomonas fuscovaginae,1150862,UPB0736,sheath brown rot,eudicots,63459,Chenopodium quinoa (related: quinoa),,,,leaf,involved in virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25394860,PubMed,10.1186/s12866-014-0274-7,BMC Microbiol. 2014 Nov 14;14(1):274,venturi@icgeb.org,,H K Patel 2014,2014,9 genes,Patel-2014-Identification of virulence associa,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4663,PHI:3425,,no data found,,,,,,Pfv102,,"102:: pKNOCK mutant of PfvUPB0736; Nfr,Kmr",,,,,50340,Pseudomonas fuscovaginae,1150862,UPB0736,sheath brown rot,eudicots,63459,Chenopodium quinoa (related: quinoa),,,,leaf,involved in virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25394860,PubMed,10.1186/s12866-014-0274-7,BMC Microbiol. 2014 Nov 14;14(1):274,venturi@icgeb.org,,H K Patel 2014,2014,9 genes,Patel-2014-Identification of virulence associa,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4664,PHI:3426,,no data found,,,,,,Pfv169,,"169:: pKNOCK mutant of PfvUPB0736; Nfr,Kmr",,,,,50340,Pseudomonas fuscovaginae,1150862,UPB0736,sheath brown rot,eudicots,63459,Chenopodium quinoa (related: quinoa),,,,leaf,involved in virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25394860,PubMed,10.1186/s12866-014-0274-7,BMC Microbiol. 2014 Nov 14;14(1):274,venturi@icgeb.org,,H K Patel 2014,2014,9 genes,Patel-2014-Identification of virulence associa,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4665,PHI:3427,,no data found,,,,,,Pfv270,,"270:: pKNOCK mutant of PfvUPB0736; Nfr,Kmr",,,,,50340,Pseudomonas fuscovaginae,1150862,UPB0736,sheath brown rot,eudicots,63459,Chenopodium quinoa (related: quinoa),,,,leaf,involved in virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25394860,PubMed,10.1186/s12866-014-0274-7,BMC Microbiol. 2014 Nov 14;14(1):274,venturi@icgeb.org,,H K Patel 2014,2014,9 genes,Patel-2014-Identification of virulence associa,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4666,PHI:3428,,no data found,,,,,,Pfv420,,"420:: pKNOCK mutant of PfvUPB0736; Nfr,Kmr",,,,,50340,Pseudomonas fuscovaginae,1150862,UPB0736,sheath brown rot,eudicots,63459,Chenopodium quinoa (related: quinoa),,,,leaf,involved in virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25394860,PubMed,10.1186/s12866-014-0274-7,BMC Microbiol. 2014 Nov 14;14(1):274,venturi@icgeb.org,,H K Patel 2014,2014,9 genes,Patel-2014-Identification of virulence associa,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4667,PHI:3429,,no data found,,,,,,Pfv445,,"445:: pKNOCK mutant of PfvUPB0736; Nfr,Kmr",,,,,50340,Pseudomonas fuscovaginae,1150862,UPB0736,sheath brown rot,eudicots,63459,Chenopodium quinoa (related: quinoa),,,,leaf,involved in virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25394860,PubMed,10.1186/s12866-014-0274-7,BMC Microbiol. 2014 Nov 14;14(1):274,venturi@icgeb.org,,H K Patel 2014,2014,9 genes,Patel-2014-Identification of virulence associa,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4668,PHI:3430,,no data found,,,,,,Pfv480,,"480:: pKNOCK mutant of PfvUPB0736; Nfr,Kmr",,,,,50340,Pseudomonas fuscovaginae,1150862,UPB0736,sheath brown rot,eudicots,63459,Chenopodium quinoa (related: quinoa),,,,leaf,involved in virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25394860,PubMed,10.1186/s12866-014-0274-7,BMC Microbiol. 2014 Nov 14;14(1):274,venturi@icgeb.org,,H K Patel 2014,2014,9 genes,Patel-2014-Identification of virulence associa,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4669,PHI:3431,UniProt,Q9L9Z9,GenBank,AF156494_1,,,MO6-24,vuuA,,,,,,,672,Vibrio vulnificus,,CECT4999,vibriosis,bony fishes,7936,Anguilla anguilla (related: european eel),,,,blood; head kidney; liver; spleen; gill,a receptor for ferric vulnibactin,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24478087,PubMed,10.1128/IAI.01117-13,Infect Immun. 2014 Feb;82(2):731-44,carmen.amaro@uv.es,Reduced growth on Iron source,D Pajuelo 2014,2014,3 genes,Pajuelo-2014-Host-nonspecific iron acquisition,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4670,PHI:3432,UniProt,Q8GRB8,GenBank,BAC15762,,,L-180,hupA,,,,,,,672,Vibrio vulnificus,,CECT4999,vibriosis,bony fishes,7936,Anguilla anguilla (related: european eel),,,,blood; head kidney; liver; spleen; gill,hemin receptor,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24478087,PubMed,10.1128/IAI.01117-13,Infect Immun. 2014 Feb;82(2):731-44,carmen.amaro@uv.es,Reduced growth on Iron source,D Pajuelo 2014,2014,3 genes,Pajuelo-2014-Host-nonspecific iron acquisition,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4671,PHI:3433,UniProt,E8VXK7,GenBank,ADV88340,,,MO6-24/O,hutR,,,,,,,672,Vibrio vulnificus,,CECT4999,vibriosis,bony fishes,7936,Anguilla anguilla (related: european eel),,,,blood; head kidney; liver; spleen; gill,hemin receptor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24478087,PubMed,10.1128/IAI.01117-13,Infect Immun. 2014 Feb;82(2):731-44,carmen.amaro@uv.es,Wild type growth on iron source,D Pajuelo 2014,2014,3 genes,Pajuelo-2014-Host-nonspecific iron acquisition,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4672,PHI:3434,UniProt,Q87CK4,GenBank,AAO28921,,,Temecula1,PD1063,,,,,,,2371,Xylella fastidiosa,,Fetzer,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,,encodes an outer membrane protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,25426629,PubMed,10.1371/journal.pone.0113504,PLoS One. 2014 Nov 26;9(11):e113504,bckirkpatrick@ucdavis.edu,,B K Pierce 2014,2014,1 gene,Pierce-2014-The Xylella fastidiosa PD1063 Prot,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4673,PHI:3435,UniProt,H8HBL1,GenBank,AFC66398,,,MGAS15252,ptsI,,,,,,,1314,Streptococcus pyogenes,293653,MGAS5005,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,phosphoenolpyruvate phosphotransferase system,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24379283,PubMed,10.1128/IAI.01271-13,Infect Immun. 2014 Mar;82(3):1192-204,kmciver@umd.ed,GAS EI mutant (ptsI) is defective for growth in several carbohydrates,K Gera 2014,2014,2 genes,Gera-2014-The phosphoenolpyruvate phosphotrans,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4674,PHI:3436,UniProt,Q1J7H9,GenBank,ABF37595,,,MGAS10750,sagB,,,,,,PHI:3435,1314,Streptococcus pyogenes,293653,MGAS5005,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,streptolysin S biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24379283,PubMed,10.1128/IAI.01271-13,Infect Immun. 2014 Mar;82(3):1192-204,kmciver@umd.ed,GAS EI mutant (ptsI) is defective for growth in several carbohydrates,K Gera 2014,2014,2 genes,Gera-2014-The phosphoenolpyruvate phosphotrans,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4675,PHI:3435,UniProt,H8HBL1,GenBank,AFC66398,,,MGAS15252,ptsI,,,,,,PHI:3436,1314,Streptococcus pyogenes,293653,MGAS5005,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,phosphoenolpyruvate phosphotransferase system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24379283,PubMed,10.1128/IAI.01271-13,Infect Immun. 2014 Mar;82(3):1192-204,kmciver@umd.ed,GAS EI mutant (ptsI) is defective for growth in several carbohydrates,K Gera 2014,2014,2 genes,Gera-2014-The phosphoenolpyruvate phosphotrans,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4676,PHI:3526,UniProt,D3QJB2,GenBank,ADD55082,,,CB9615,lacA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,lactose negativity,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25362512,PubMed,10.1007/s00284-014-0720-7,Curr Microbiol. 2014 Nov 2,liubin1981@nankai.edu.cn,The lac promoter sequence of E. Coli K12 MG1655 was constitutively expressed.,L Jiang 2014,2014,1 gene,Jiang-2014-Loss of the lac Operon Contributes,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4677,PHI:3437,UniProt,J9MT86,Broad,FOXG_06120,,,MN25,Sho1,,hph(B):sho1:pGemT; phleo(B):sho1:pGemT (replacement with Hygromycin or phleomycin),,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,fruit,tetraspan transmembrane protein,,,,reduced virulence,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4678,PHI:3438,UniProt,J9N257,Broad,FOXG_09254,,,,Msb2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,fruit,mucin-like membrane protein,,,,reduced virulence,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4679,PHI:3437,UniProt,J9MT86,Broad,FOXG_06120,,,MN25,Sho1,,hph(B):sho1:pGemT; phleo(B):sho1:pGemT (replacement with Hygromycin or phleomycin),,,,PHI:3438,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,fruit,tetraspan transmembrane protein,,,,reduced virulence,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4680,PHI:3438,UniProt,J9N257,Broad,FOXG_09254,,,,Msb2,,,,,,PHI:3437,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Daniela,,,fruit,mucin-like membrane protein,,,,reduced virulence,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4681,PHI:3437,UniProt,J9MT86,Broad,FOXG_06120,,,MN25,Sho1,,hph(B):sho1:pGemT; phleo(B):sho1:pGemT (replacement with Hygromycin or phleomycin),,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,tetraspan transmembrane protein,,,,reduced virulence,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4682,PHI:3438,UniProt,J9N257,Broad,FOXG_09254,,,,Msb2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,mucin-like membrane protein,,,,reduced virulence,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4683,PHI:3437,UniProt,J9MT86,Broad,FOXG_06120,,,MN25,Sho1,,hph(B):sho1:pGemT; phleo(B):sho1:pGemT (replacement with Hygromycin or phleomycin),,,,PHI:3438,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,tetraspan transmembrane protein,,,,reduced virulence,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4684,PHI:3438,UniProt,J9N257,Broad,FOXG_09254,,,,Msb2,,,,,,PHI:3437,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,mucin-like membrane protein,,,,reduced virulence,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4685,PHI:3437,UniProt,J9MT86,Broad,FOXG_06120,,,MN25,Sho1,,hph(B):sho1:pGemT; phleo(B):sho1:pGemT (replacement with Hygromycin or phleomycin),,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,tetraspan transmembrane protein,,,,unaffected pathogenicity,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4686,PHI:3438,UniProt,J9N257,Broad,FOXG_09254,,,,Msb2,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mucin-like membrane protein,,,,unaffected pathogenicity,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4687,PHI:3437,UniProt,J9MT86,Broad,FOXG_06120,,,MN25,Sho1,,hph(B):sho1:pGemT; phleo(B):sho1:pGemT (replacement with Hygromycin or phleomycin),,,,PHI:3438,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,tetraspan transmembrane protein,,,,unaffected pathogenicity,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4688,PHI:3438,UniProt,J9N257,Broad,FOXG_09254,,,,Msb2,,,,,,PHI:3437,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,mucin-like membrane protein,,,,unaffected pathogenicity,,,yes,yes,,,,reduced,,no,congo red; calcofluor white,,,,,,gene deletion: full; gene complementation,,,RP,25382187,PubMed,10.1111/mpp.12217,Mol Plant Pathol. 2014 Nov 10.,ge2dipia@uco.es,Increased sensitivity to the cell wall targeting compounds.,E Perez-Nadales 2014,2014,2 genes,Perez-Nadales-2014-The transmembrane protein S,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4689,PHI:3439,UniProt,N1KZN0,GenBank,CCV53898,,,YE12/03,InvA,,"deltainvA, Kanr",,,,,630,Yersinia enterocolitica,1262466,YE12/03,yersiniosis,even-toed ungulates,9823,Sus scrofa (related: pig),Mini-Lewe,,,tonsil; jejunum; ileum; cecum; colon; mesenteric lymph node; liver; kidney; spleen,primary adhesion factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24343656,PubMed,10.1128/IAI.01001-13,Infect Immun. 2014 Mar;82(3):960-9,petra.dersch@helmholtz-hzi.de,Invasin is important for persistence ofY. enterocoliticaO:3in the intestinal tract of pigs and mice,J Schaake 2014,2014,1 gene,Schaake-2014-Essential role of invasin for col,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4690,PHI:3439,UniProt,N1KZN0,GenBank,CCV53898,,,YE12/03,InvA,,"YE15 Y1, PdeltainvA IS1667",,,,,630,Yersinia enterocolitica,1262466,YE12/03,yersiniosis,even-toed ungulates,9823,Sus scrofa (related: pig),Mini-Lewe,,,tonsil; jejunum; ileum; cecum; colon; mesenteric lymph node; liver; kidney; spleen,primary adhesion factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,24343656,PubMed,10.1128/IAI.01001-13,Infect Immun. 2014 Mar;82(3):960-9,petra.dersch@helmholtz-hzi.de,Presence of IS1667inserted into theinvApromoter region of O:3 strains increases colonization of the intestinal tract of pigs,J Schaake 2014,2014,1 gene,Schaake-2014-Essential role of invasin for col,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4691,PHI:3439,UniProt,N1KZN0,GenBank,CCV53898,,,YE12/03,InvA,,"deltainvA, Kanr",,,,,630,Yersinia enterocolitica,1262466,YE12/03,yersiniosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tonsil; jejunum; ileum; cecum; colon; mesenteric lymph node; liver; kidney; spleen,primary adhesion factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24343656,PubMed,10.1128/IAI.01001-13,Infect Immun. 2014 Mar;82(3):960-9,petra.dersch@helmholtz-hzi.de,Invasin is important for persistence ofY. enterocoliticaO:3in the intestinal tract of pigs and mice,J Schaake 2014,2014,1 gene,Schaake-2014-Essential role of invasin for col,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4692,PHI:3440,UniProt,Q9HV74,GenBank,AE004886_3,,,PAO1,CbrA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; peritoneal fluid,sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24379284,PubMed,10.1128/IAI.01527-13,Infect Immun. 2014 Mar;82(3):1256-67,bob@hancocklab.com,,A T Y Yeung 2014,2014,1 gene,Yeung-2014-Requirement of the Pseudomonas aeru,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4693,PHI:3440,UniProt,Q9HV74,GenBank,AE004886_3,,,PAO1,CbrA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung; bronchoalveolar lavage fluid,sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24379284,PubMed,10.1128/IAI.01527-13,Infect Immun. 2014 Mar;82(3):1256-67,bob@hancocklab.com,,A T Y Yeung 2014,2014,1 gene,Yeung-2014-Requirement of the Pseudomonas aeru,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4694,PHI:3440,UniProt,Q9HV74,GenBank,AE004886_3,,,PAO1,CbrA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),AX2,,,,sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24379284,PubMed,10.1128/IAI.01527-13,Infect Immun. 2014 Mar;82(3):1256-67,bob@hancocklab.com,,A T Y Yeung 2014,2014,1 gene,Yeung-2014-Requirement of the Pseudomonas aeru,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4695,PHI:3440,UniProt,Q9HV74,GenBank,AE004886_3,,,PAO1,CbrA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,lung,sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24379284,PubMed,10.1128/IAI.01527-13,Infect Immun. 2014 Mar;82(3):1256-67,bob@hancocklab.com,,A T Y Yeung 2014,2014,1 gene,Yeung-2014-Requirement of the Pseudomonas aeru,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4696,PHI:3441,UniProt,Q833J1,GenBank,AAO81706,,,V583,tcpF,,,,,,,1351,Enterococcus faecalis,,E99,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,encodes a protein resembling mammalian and bacterial TIR proteins,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25369374,PubMed,10.1371/journal.pone.0112010,PLoS One. 2014 Nov 4;9(11):e112010,nathan-shankar@ouhsc.edu,"A mutant lacking the tcpF gene was attenuated for survival in macrophages, with increased ability to activate NF-kB compared to the wild type strain. No appreciable difference in bacterial persistence, dissemination or pathogenesis was observed between the wild type and mutant in a mouse peritonitis model however, which suggested either a subtle role for TcpF or functional overlap with other redundant factor(s) in this virulence model.",J Zou 2014,2014,1 gene,Zou-2014-A TIR Domain Protein from E. faecalis,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4697,PHI:3442,UniProt,P11437,GenBank,AAA25725,,,,pPg6L3/ AvrA,,,,,,,317,Pseudomonas syringae,318,pv. glycinea race 6,bacterial blight (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,16593517,PubMed,10.1073/pnas.81.19.6024,Proc Natl Acad Sci U S A,,,B J STASKAWICZ 1984,1984,1 gene,Staskawicz-1984-Cloned avirulence gene of Pseu,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4698,PHI:3442,UniProt,P11437,GenBank,AAA25725,,,,pPg6L3/ AvrA,,,,,,,317,Pseudomonas syringae,318,pv. glycinea race 6,bacterial blight (soybean),eudicots,3847,Glycine max (related: soybean),cv. Norchief,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,16593517,PubMed,10.1073/pnas.81.19.6024,Proc Natl Acad Sci U S A,,,B J STASKAWICZ 1984,1984,1 gene,Staskawicz-1984-Cloned avirulence gene of Pseu,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4699,PHI:3442,UniProt,P11437,GenBank,AAA25725,,,,pPg6L3/ AvrA,,,,,,,317,Pseudomonas syringae,318,pv. glycinea race 6,bacterial blight (soybean),eudicots,3847,Glycine max (related: soybean),cv. Peking,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,16593517,PubMed,10.1073/pnas.81.19.6024,Proc Natl Acad Sci U S A,,,B J STASKAWICZ 1984,1984,1 gene,Staskawicz-1984-Cloned avirulence gene of Pseu,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4700,PHI:3442,UniProt,P11437,GenBank,AAA25725,,,,pPg6L3/ AvrA,,,,,,,317,Pseudomonas syringae,318,pv. glycinea race 6,bacterial blight (soybean),eudicots,3847,Glycine max (related: soybean),cv. Flambeau,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,16593517,PubMed,10.1073/pnas.81.19.6024,Proc Natl Acad Sci U S A,,,B J STASKAWICZ 1984,1984,1 gene,Staskawicz-1984-Cloned avirulence gene of Pseu,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4701,PHI:3443,UniProt,M7UB04,GenBank,EMR83808,,,BcDW1,BcNoxD,,,,BcNoxA,UniProt: B0BES1,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,NADPH oxidase complex,,,,reduced virulence,,no,no,yes,,reduced,,wild type,aberrant,no,H2O2; menadione; NaCl,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,RP,25402961,PubMed,10.1111/mmi.12869,Mol Microbiol. 2014 Nov 17,tudzyns@uni-muenster.de,"Both deltabcnoxA and deltabcnoxD were more sensitive towards H2O2, while growth on menadione was comparable to the WT. Furthermore, growth under conditions of osmotic stress (NaCl) was not significantly altered in the mutants.",U Siegmund 2014,2014,2 genes,"Siegmund-2014-BcNoxD, a putative ER protein, i",Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4702,PHI:3444,UniProt,B0BES1,GenBank,CAP12516,,,B05.10,BcNoxA,,,,BcNoxD,UniProt: M7UB04,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,NADPH oxidase complex,,,,reduced virulence,,no,no,yes,,reduced,,wild type,,no,H2O2; menadione; NaCl,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,RP,25402961,PubMed,10.1111/mmi.12869,Mol Microbiol. 2014 Nov 17,tudzyns@uni-muenster.de,"Both deltabcnoxA and deltabcnoxD were more sensitive towards H2O2, while growth on menadione was comparable to the WT. Furthermore, growth under conditions of osmotic stress (NaCl) was not significantly altered in the mutants.",U Siegmund 2014,2014,2 genes,"Siegmund-2014-BcNoxD, a putative ER protein, i",Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4703,PHI:3445,UniProt,Q81Z69,GenBank,AAP24433,,,Ames,yceG,,,,,,PHI:3446,1392,Bacillus anthracis,260799,Sterne,anthrax,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,tellurite resistance,,,,reduced virulence,,,,,,,,,,no,H2O2; nisin; bacitracin; polymyxin,H2O2: CHEBI:16240; nisin: CHEBI:71629; bacitracin: CHEBI:28669; polymyxin: CHEBI:59062,,,,,gene mutation: characterised; gene complementation,,,RP,24366250,PubMed,10.1128/IAI.01614-13,Infect Immun. 2014 Mar;82(3):1132-40,s.mcgillivray@tcu.edu,Loss of yceGH rendered the mutants more sensitive to tellurite toxicity as well as to host defenses such as reactive oxygen species and the cathelicidin family of antimicrobial peptides.,S E Franks 2014,2014,2 genes,Franks-2014-Novel role for the yceGH tellurite,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4704,PHI:3446,UniProt,Q81Z68,GenBank,AAP24434,,,Ames,yceH,,,,,,PHI:3445,1392,Bacillus anthracis,260799,Sterne,anthrax,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,tellurite resistance,,,,reduced virulence,,,,,,,,,,no,H2O2; nisin; bacitracin; polymyxin,H2O2: CHEBI:16240; nisin: CHEBI:71629; bacitracin: CHEBI:28669; polymyxin: CHEBI:59062,,,,,gene mutation: characterised; gene complementation,,,RP,24366250,PubMed,10.1128/IAI.01614-13,Infect Immun. 2014 Mar;82(3):1132-40,s.mcgillivray@tcu.edu,Loss of yceGH rendered the mutants more sensitive to tellurite toxicity as well as to host defenses such as reactive oxygen species and the cathelicidin family of antimicrobial peptides.,S E Franks 2014,2014,2 genes,Franks-2014-Novel role for the yceGH tellurite,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4705,PHI:3447,UniProt,C5VY20,GenBank,CAR44372,,,P1/7,orf2,,,,,,,1307,Streptococcus suis,1184252,S735,streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: pig),,,,central nervous system; pericardium; peritoneum; pleura; joint,,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25384512,PubMed,10.1186/s12866-014-0264-9,BMC Microbiol. 2014 Nov 12;14(1):264,astrid.degreeff@wur.nl,There is a correlation between high orf2expression and virulence.,A de Greeff 2014,2014,1 gene,de Greeff-2014-A naturally occurring nucleotid,Batch043B,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4706,PHI:3448,UniProt,B5Y383,GenBank,ACI10823,,,342,pgaC,,CG43SDpgaC::Tcr,,,,,573,Klebsiella pneumoniae,1244085,CG43,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,production of poly-b-linkedN-acetylglucosamine,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25450884,PubMed,10.1016/j.micpath.2014.11.005,Microb Pathog. 2014 Dec;77:89-99,luminchi@csmu.edu.tw,The loss of pgaC affected the production of PNAG attenuated the enhancement of in vitro biofilm formation upon the addition of bile salts mixture and attenuated virulence.,K Chen 2014,2014,1 gene,Chen-2014-The role of pgaC in Klebsiella pneum,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4707,PHI:3449,UniProt,D2TV46,GenBank,YP_003368469,,,ICC168,crc1,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestine (feces),class 1 serine protease autotransporter,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24711562,PubMed,10.1128/IAI.01518-13,Infect Immun. 2014 Jun;82(6):2626-36,jpn2r@virginia.edu,,V Vijayakumar 2014,2014,1 gene,Vijayakumar-2014-Role of Class 1 Serine Protea,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4708,PHI:3450,UniProt,B4EHQ6,GenBank,CAR54082,,,J2315,BCAM0224,,,,,,,95486,Burkholderia cenocepacia,216591,J2315,nosocomial infection,primates,9606,Homo sapiens (related: human),16HBE14o- cell line,,,bronchial epithelial cell line,multifunctional trimeric autotransporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24659767,PubMed,10.1128/JB.00061-14,J Bacteriol. 2014 Jun;196(11):1968-79,afialho@tecnico.ulisboa.pt,BCAM0224 occurs on the bacterial surface and adopts a trimeric conformation. BCAM0224 is needed for earlier stages of biofilm formation and is required for swarming motility and adhesion.,D Mil-Homens 2014,2014,1 gene,Mil-Homens-2014-Characterization of BCAM0224,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4709,PHI:3451,UniProt,B4EJI4,GenBank,CAR55348,,,J2315,BceR,,"bceR- mutant, TmpR 9trimethoprim resistance)",,,,,95486,Burkholderia cenocepacia,985075,K56-2,nosocomial infection,eudicots,3879,Medicago sativa (related: alfalfa),cv. 57Q77,,,seedling,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25519693,PubMed,10.1007/s00284-014-0744-z,Curr Microbiol. 2014 Dec 18,weingartc@denison.edu,,C R Merry 2014,2014,1 gene,Merry-2014-Characterization of a Novel Two-Com,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4710,PHI:3452,,no data found,,,,,,ANXA1,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,ANXA1,UniProt: P10107; GenBank: CAA30371,lung; spleen,immune response,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25533809,PubMed,10.1016/j.imbio.2014.12.001,Immunobiology. 2014 Dec 10. pii: S0171-2985(14)00270-8,lina_lim@nuhs.edu.sg,,K H Q Vanessaa 2014,2014,1 gene,Vanessa-2014-Absence of Annexin A1 impairs hos,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4711,PHI:3453,UniProt,Q5KM27,GenBank,AAW41592,,,JEC21,ktr3,,MATalpha ktr3::NAT#159/KTR3::NEO,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,protein O-mannosylation,,,,reduced virulence,,,,,,,,,,no,hygromycin B; vanadate; calcofluor white; Congo red; NaCl; sorbitol,hygromycin B: CHEBI:16976; vanadate: CHEBI:46442; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:17924,,,,,gene mutation: characterised; gene complementation,,,RP,25477510,PubMed,10.1074/jbc.M114.607705,J Biol Chem. 2014 Dec 4. pii: jbc.M114.607705,hyunkang@cau.ac.kr,"Mutants are not sensitive to cell wall pertubers, but sensitive to osmotic stress by NaCl which can be compensated by Sorbitol.",D Lee 2014,2014,1 gene,Lee-2014-Unraveling the novel structure and bi,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4712,PHI:3454,UniProt,Q881Q3,GenBank,ELS43793,,,B64,sylC,,,,,,,317,Pseudomonas syringae,321,pv. syringae strain BRIP34876,bacterial speck,monocots,4565,Triticum aestivum (related: bread wheat),cv. Chinese Spring,,,leaf,a peptide derivative that inhibits the eukaryotic proteasome,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,25472590,PubMed,10.1186/s12866-014-0304-5,BMC Microbiol. 2014 Dec 4;14(1):304,adud@biosustain.dtu.dk,,A Dudnik 2014,2014,1 gene,Dudnik-2014-Virulence determinants of Pseudomo,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4713,PHI:3455,UniProt,J9VIH5,GenBank,AFR93216,,,H99,Apt1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,flippase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24337112,PubMed,10.1128/EC.00273-13,Eukaryot Cell. 2014 Jun;13(6):715-26,marciolr@cdts.fiocruz.br,Lack of Apt1 affects Golgi morphology and GXM synthesis and transport.,J Rizzo 2013,2013,1 gene,Rizzo-2013-Role of the Apt1 protein in polysac,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4714,PHI:3456,UniProt,Q2A589,GenBank,CAJ78765,,,LVS,FTT0831c/FTL_0325,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,lung; spleen; liver,lipoprotein involved in cell dicision and virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24778115,PubMed,10.1128/IAI.00102-14,Infect Immun. 2014 Jul;82(7):2935-48,Michael.Norgard@UTSouthwestern.edu,,G T Robertson 2014,2014,1 gene,Robertson-2014-FTT0831c_FTL_0325 contributes t,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4715,PHI:3457,UniProt,J9VMW8,GenBank,AFR93914,,,H99,PHO84,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; kidney; liver; spleen,phosphate acquisition and storage,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24711572,PubMed,10.1128/IAI.01607-14,Infect Immun. 2014 Jul;82(7):2697-712,kronstad@msl.ubc.ca,"Mutants had perturbed the formation of virulence factors (capsule and melanin), reduced survival in macrophages, and attenuated virulence in a mouse model of cryptococcosis.",M Kretschmer 2014,2014,4 genes,Kretschmer-2014-Defects in phosphate acquisiti,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4716,PHI:3527,UniProt,J9W1N5,GenBank,AFR98889,,,H99,PHO840,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; kidney; liver; spleen,phosphate acquisition and storage,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24711572,PubMed,10.1128/IAI.01607-14,Infect Immun. 2014 Jul;82(7):2697-712,kronstad@msl.ubc.ca,"Mutants had perturbed the formation of virulence factors (capsule and melanin), reduced survival in macrophages, and attenuated virulence in a mouse model of cryptococcosis.",M Kretschmer 2014,2014,4 genes,Kretschmer-2014-Defects in phosphate acquisiti,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4717,PHI:3528,UniProt,J9VNZ8,GenBank,AFR94339,,,H99,PHO89,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; kidney; liver; spleen,phosphate acquisition and storage,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24711572,PubMed,10.1128/IAI.01607-14,Infect Immun. 2014 Jul;82(7):2697-712,kronstad@msl.ubc.ca,"Mutants had perturbed the formation of virulence factors (capsule and melanin), reduced survival in macrophages, and attenuated virulence in a mouse model of cryptococcosis.",M Kretschmer 2014,2014,4 genes,Kretschmer-2014-Defects in phosphate acquisiti,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4718,PHI:3529,UniProt,J9VQL2,GenBank,AFR94879,,,H99,VTC4,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; kidney; liver; spleen,phosphate acquisition and storage,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24711572,PubMed,10.1128/IAI.01607-14,Infect Immun. 2014 Jul;82(7):2697-712,kronstad@msl.ubc.ca,"The vtc4 mutant behaved like the wild-type strain in interactions with macrophages and in the mouse infectionmodel. However, the fungal load in the lungs was significantly increased in mice infected with vtc4 deletion mutants.",M Kretschmer 2014,2014,4 genes,Kretschmer-2014-Defects in phosphate acquisiti,Batch044,2015-01-01,MC,,,,,,,,,,,,,
,,Record 4719,PHI:3492,UniProt,P13835,EMBL,AAA25726.1,,,Pseudomonas syringae pv. glycinea race 4,avrB,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Harosoy,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,resistance,"HR, rapid ion leakage, visual cell death",other evidence,VIGS using BPMV- empty vector control,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4720,PHI:3492,UniProt,P13835,EMBL,AAA25726.1,,,Pseudomonas syringae pv. glycinea race 4,avrB,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Merit,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,resistance,"HR, rapid ion leakage, visual cell death",other evidence,VIGS using BPMV- empty vector control,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4721,PHI:3492,UniProt,P13835,EMBL,AAA25726.1,,,Pseudomonas syringae pv. glycinea race 4,avrB,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Norchief,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,resistance,"HR, rapid ion leakage, visual cell death",other evidence,VIGS using BPMV- empty vector control,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4722,PHI:3492,UniProt,P13835,EMBL,AAA25726.1,,,Pseudomonas syringae pv. glycinea race 4,avrB,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Harosoy,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,susceptible,"no HR, reduced ion leakage, no visual cell death, 9 fold more bacterial accumulation",other evidence,VIGS using BPMV- GmNDR1 (to both genes),,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4723,PHI:3492,UniProt,P13835,EMBL,AAA25726.1,,,Pseudomonas syringae pv. glycinea race 4,avrB,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Merit,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,susceptible,"no HR, reduced ion leakage, no visual cell death, 9 fold more bacterial accumulation",other evidence,VIGS using BPMV- GmNDR1 (to both genes),,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4724,PHI:3492,UniProt,P13835,EMBL,AAA25726.1,,,Pseudomonas syringae pv. glycinea race 4,avrB,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Norchief,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,susceptible,"no HR, reduced ion leakage, no visual cell death, 9 fold more bacterial accumulation",other evidence,VIGS using BPMV- GmNDR1 (to both genes),,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4725,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),avrB2,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Flambeau,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,resistance,"HR, rapid ion leakage, visual cell death",other evidence,VIGS using BPMV- empty vector control,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4726,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),avrB2,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Flambeau,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,susceptible,"no HR, no ion leakage, no visual cell death, bacterial accumulation equal to control vir strain, abolished rpg3-derived resistance",other evidence,VIGS using BPMV- GmNDR1 (to both genes),,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4727,PHI:3494,UniProt,Q48B68,EMBL,AAZ37987.1,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),avrD1,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Flambeau,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,resistance,"HR, rapid ion leakage, milder visual cell death",other evidence,VIGS using BPMV- empty vector control,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4728,PHI:3494,UniProt,Q48B68,EMBL,AAZ37987.1,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),avrD1,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Flambeau,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,susceptible,"no HR, no ion leakage, no visual cell death, bacterial accumulation slightly less than control vir strain, compromised rpg4-derived resistance",other evidence,VIGS using BPMV- GmNDR1 (to both genes),,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4729,PHI:3494,UniProt,Q48B68,EMBL,AAZ37987.1,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),avrD1,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Merit,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,wild-type susceptiblity,disease,other evidence,VIGS using BPMV- GmNDR1 (to both genes),,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4730,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),avrB2,,,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),cv. Merit,GmNDR1a; GmNDR1b,GenBank: GU132856; GenBank: GU132854,leaf,effector protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,wild-type susceptiblity,disease,other evidence,VIGS using BPMV- GmNDR1 (to both genes),,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4731,PHI:3492,UniProt,P13835,EMBL,AAA25726.1,,,Pseudomonas syringae pv. glycinea race 4,avrB,,FLAG-tagged,,,,,317,Pseudomonas syringae,321,pv. syringae,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmNDR1a; GmNDR1b,UniProt: GU132856; UniProt: GU132854,no binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmNDR1a and 1b, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4732,PHI:3495,UniProt,Q4ZYH0,EMBL,AAY35802.1,,,Pseudomonas syringae pv. maculicola str. M6,AvrRPM1,,FLAG-tagged,,,,,317,Pseudomonas syringae,59511,pv. maculicola,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmNDR1a; GmNDR1b,UniProt: GU132856; UniProt: GU132854,no binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmNDR1a and 1b, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4733,PHI:3496,UniProt,E2MM96,EMBL,EEB56913.1,,,Pseudomonas syringae pv. tomato T1,AvrA1,,FLAG-tagged,,,,,317,Pseudomonas syringae,,,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmNDR1a; GmNDR1b,UniProt: GU132856; UniProt: GU132854,no binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmNDR1a and 1b, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4734,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,FLAG-tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmNDR1a,UniProt: GU132856,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmNDR1a and 1b, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4735,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,FLAG-tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmNDR1b,UniProt: GU132854,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmNDR1a and 1b, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4736,PHI:3494,UniProt,Q48B68,EMBL,AAZ37987.1,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrD1,,FLAG-tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmNDR1a,UniProt: GU132856,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmNDR1a and 1b, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4737,PHI:3494,UniProt,Q48B68,EMBL,AAZ37987.1,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrD1,,FLAG-tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmNDR1b,UniProt: GU132854,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmNDR1a and 1b, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4738,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,Split YFP,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmNDR1a; GmNDR1b,UniProt: GU132856; UniProt: GU132854,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4739,PHI:3494,UniProt,Q48B68,EMBL,AAZ37987.1,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrD1,,Split YFP,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmNDR1a; GmNDR1b,UniProt: GU132856; UniProt: GU132854,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4740,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,Split YFP,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINa,,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4741,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,FLAG -tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINa,,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmRINa, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4742,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,Split YFP,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINb,,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4743,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,FLAG -tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINb,,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmRINb, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4744,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,Split YFP,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINc,,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4745,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,FLAG -tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINc,,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmRINc, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4746,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,Split YFP,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINd,,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4747,PHI:3493,UniProt,Q48B66,EMBL,AAZ37967,,,Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6),AvrB2,,FLAG -tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINd,,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmRINd, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4748,PHI:3496,UniProt,E2MM96,EMBL,EEB56913.1,,,Pseudomonas syringae pv. tomato T1,AvrA1,,Split YFP,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINa,,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4749,PHI:3496,UniProt,E2MM96,EMBL,EEB56913.1,,,Pseudomonas syringae pv. tomato T1,AvrA1,,FLAG -tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINa,,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmRINa, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4750,PHI:3496,UniProt,E2MM96,EMBL,EEB56913.1,,,Pseudomonas syringae pv. tomato T1,AvrA1,,Split YFP,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINb,,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4751,PHI:3496,UniProt,E2MM96,EMBL,EEB56913.1,,,Pseudomonas syringae pv. tomato T1,AvrA1,,FLAG -tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINb,,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmRINb, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4752,PHI:3496,UniProt,E2MM96,EMBL,EEB56913.1,,,Pseudomonas syringae pv. tomato T1,AvrA1,,Split YFP,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINc,,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4753,PHI:3496,UniProt,E2MM96,EMBL,EEB56913.1,,,Pseudomonas syringae pv. tomato T1,AvrA1,,FLAG -tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINc,,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmRINc, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4754,PHI:3496,UniProt,E2MM96,EMBL,EEB56913.1,,,Pseudomonas syringae pv. tomato T1,AvrA1,,Split YFP,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINd,,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4755,PHI:3496,UniProt,E2MM96,EMBL,EEB56913.1,,,Pseudomonas syringae pv. tomato T1,AvrA1,,FLAG -tagged,,,,,317,Pseudomonas syringae,875330,pv. glycinea race 4,bacterial speck,eudicots,3847,Glycine max (related: soybean),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,GmRINd,,binding,,other evidence,"co-expression in N. benthamiana using the pSITE vectors; MyC-tagged GmRINd, FLAG tagged Avr, IP using FLAG specific antibodies",,KHK; MU,24372490,PubMed,10.1111/nph.12654,Selote et al. New Phytologis (2014) 202: 485-498,apkach2@uky.edu,,Devaarshi Selote,2013,,Selotte 2013 marked up for training,RRes01,2014-08-01,RRes,Aardra Kachroo,,,,,,,,,,,,
,,Record 4756,PHI:3458,UniProt,K9GB51,GenBank,EKV12123,,,Pd1,PdGcs1,,,,,,,36651,Penicillium digitatum,,PdKH8,green mold,eudicots,85571,Citrus reticulata (related: tangerine),,,,fruit,biosynthesis of glucosylceramides,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,25449268,PubMed,10.1016/j.bbrc.2014.10.142,Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):165-71,hyli@zju.edu.cn,,C Zhu 2014,2014,1 gene,Zhu-2014-Glucosylceramides are required for my,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4757,PHI:3459,UniProt,Q4QFI1,GenBank,CAJ03227,,,Friedlin,NTPDase1,,,,,,,5664,Leishmania major,,MHOM/SU/73/5-ASKH,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,nucleoside triphosphate diphosphohydrolases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25521752,PubMed,10.1371/journal.pntd.0003402,PLoS Negl Trop Dis. 2014 Dec 18;8(12):e3402,fsansom@unimelb.edu.au,"Lag in lesion development when infections in susceptible BALB/c mice were initiated with promastigotes, but not with the obligate intracellular amastigote stage.",F M Sansom 2014,2014,2 gene,Sansom-2014-Golgi-Located NTPDase1 of Leishman,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4758,PHI:3460,UniProt,Q4QHK3,GenBank,CAJ02396,,,Friedlin,NTPDase2,,,,,,,5664,Leishmania major,,MHOM/SU/73/5-ASKH,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,nucleoside triphosphate diphosphohydrolases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25521752,PubMed,10.1371/journal.pntd.0003402,PLoS Negl Trop Dis. 2014 Dec 18;8(12):e3402,fsansom@unimelb.edu.au,,F M Sansom 2014,2014,2 gene,Sansom-2014-Golgi-Located NTPDase1 of Leishman,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4759,PHI:3461,UniProt,Q53591,GenBank,AAA56749,,,Serotype III GBS 3502,hylB,,"pSET4s::hylB (pSET4S vector digested with the same restriction enzymes to generate thehylBknockout vector, pSET4S::hylB)",,,,,1311,Streptococcus agalactiae,1203670,GD201008-001,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; spleen; brain,encoding extracellular hyaluronidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24711564,PubMed,10.1128/IAI.00022-14,Infect Immun. 2014 Jun;82(6):2615-25,liuyongjie@njau.edu.cn,,Z Wang 2014,2014,1 gene,Wang-2014-Two Novel Functions of Hyaluronidase,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4760,PHI:3461,UniProt,Q53591,GenBank,AAA56749,,,Serotype III GBS 3502,hylB,,"pSET4s::hylB (pSET4S vector digested with the same restriction enzymes to generate thehylBknockout vector, pSET4S::hylB)",,,,,1311,Streptococcus agalactiae,1203670,GD201008-001,pneumonia; meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,encoding extracellular hyaluronidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24711564,PubMed,10.1128/IAI.00022-14,Infect Immun. 2014 Jun;82(6):2615-25,liuyongjie@njau.edu.cn,,Z Wang 2014,2014,1 gene,Wang-2014-Two Novel Functions of Hyaluronidase,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4761,PHI:3462,UniProt,A0A023Y9U3,GenBank,KJ149475,,,B285,RpfF,,,,,,,40324,Stenotrophomonas maltophilia,,E77,nosocomial infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,diffusible signal factor production,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene mutation; gene complementation,,,RP,24769700,PubMed,10.1128/JB.01540-14,J Bacteriol. 2014 Jul;196(13):2431-42,Xavier.Daura@uab.cat,,P Huedo 2014,2014,1 gene,Huedo-2014-Two different rpf clusters distribu,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4762,PHI:3462,UniProt,A0A023Y9U3,GenBank,KJ149475,,,B285,RpfF,,,,,,,40324,Stenotrophomonas maltophilia,1451188,M30,nosocomial infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,diffusible signal factor production,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene mutation; gene complementation,,,RP,24769700,PubMed,10.1128/JB.01540-14,J Bacteriol. 2014 Jul;196(13):2431-42,Xavier.Daura@uab.cat,,P Huedo 2014,2014,1 gene,Huedo-2014-Two different rpf clusters distribu,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4763,PHI:3462,UniProt,A0A023Y9U3,GenBank,KJ149475,,,B285,RpfF,,,,,,,40324,Stenotrophomonas maltophilia,,E77,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,diffusible signal factor production,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene mutation; gene complementation,,,RP,24769700,PubMed,10.1128/JB.01540-14,J Bacteriol. 2014 Jul;196(13):2431-42,Xavier.Daura@uab.cat,,P Huedo 2014,2014,1 gene,Huedo-2014-Two different rpf clusters distribu,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4764,PHI:3462,UniProt,A0A023Y9U3,GenBank,KJ149475,,,B285,RpfF,,,,,,,40324,Stenotrophomonas maltophilia,1451188,M30,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,diffusible signal factor production,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene mutation; gene complementation,,,RP,24769700,PubMed,10.1128/JB.01540-14,J Bacteriol. 2014 Jul;196(13):2431-42,Xavier.Daura@uab.cat,,P Huedo 2014,2014,1 gene,Huedo-2014-Two different rpf clusters distribu,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4765,PHI:3463,UniProt,A0A097BVQ8,GenBank,KJ867495,,,221,HMTp210,,,,,,,728,Avibacterium paragallinarum,,TW94,infectious coryza,birds,9031,Gallus gallus (related: chicken),,,,,production of haemagglutination,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25465664,PubMed,10.1016/j.vetmic.2014.10.013,Vet Microbiol. 2014 Dec 5;174(3-4):474-82,pcchang@mail.nchu.edu.tw,,Y Wang 2014,2014,1 gene,Wang-2014-The haemagglutinin of Avibacterium p,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4766,PHI:3463,UniProt,A0A097BVQ8,GenBank,KJ867495,,,221,HMTp210,,,,,,,728,Avibacterium paragallinarum,,TW07,infectious coryza,birds,9031,Gallus gallus (related: chicken),,,,,production of haemagglutination,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25465664,PubMed,10.1016/j.vetmic.2014.10.013,Vet Microbiol. 2014 Dec 5;174(3-4):474-82,pcchang@mail.nchu.edu.tw,,Y Wang 2014,2014,1 gene,Wang-2014-The haemagglutinin of Avibacterium p,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4767,PHI:3464,UniProt,P67320,GenBank,AAK33390,,,M1 GAS,nrdR,,,,,,,1314,Streptococcus pyogenes,,1529,toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),Slc:ICR,,,skin,regulator,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25469586,PubMed,10.1111/apm.12340,APMIS. 2014 Dec 3,tadaoh@med.nagoya-cu.ac.jp,"The nrdR and partialdnaBknockout strain, but not thenrdR-only knockout strain, was less virulent compared with the parental strain.",Y Zhang 2014,2014,2 genes,Zhang-2014-Analysis of the roles of NrdR and D,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4768,PHI:3465,UniProt,H8HCN1,GenBank,AFC65667,,,MGAS15252,dnaB,,,,,,PHI:3464,1314,Streptococcus pyogenes,,1529,toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),Slc:ICR,,,skin,DNA replication/repair protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25469586,PubMed,10.1111/apm.12340,APMIS. 2014 Dec 3,tadaoh@med.nagoya-cu.ac.jp,"The nrdR and partialdnaBknockout strain, but not thenrdR-only knockout strain, was less virulent compared with the parental strain.",Y Zhang 2014,2014,2 genes,Zhang-2014-Analysis of the roles of NrdR and D,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4769,PHI:3464,UniProt,P67320,GenBank,AAK33390,,,M1 GAS,nrdR,,,,,,PHI:3465,1314,Streptococcus pyogenes,,1529,toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),Slc:ICR,,,skin,regulator,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25469586,PubMed,10.1111/apm.12340,APMIS. 2014 Dec 3,tadaoh@med.nagoya-cu.ac.jp,"The nrdR and partialdnaBknockout strain, but not thenrdR-only knockout strain, was less virulent compared with the parental strain.",Y Zhang 2014,2014,2 genes,Zhang-2014-Analysis of the roles of NrdR and D,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4770,PHI:3466,UniProt,A1ABF3,GenBank,ABJ00993,,,APEC O1,RstA,,E058deltarstA::cat ( The catcassette was inserted into the rstA gene at the EcoRV site to form pMD-rstA-cat),,,,,562,Escherichia coli,,E058,colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen; lung; kidney,part of a two component regulatory system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25461694,PubMed,10.1016/j.meegid.2014.11.022,Infect Genet Evol. 2015 Jan;29:180-8,gsong@yzu.edu.cn,,Q Gao 2014,2014,1 gene,Gao-2015-RstA is required for the virulence of,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4771,PHI:3467,UniProt,Q4WCW8,GenBank,EAL85770,,,Af293,mtfA,chromosome 6,,,,,,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,A veA-dependent gene encoding a novel C2H2 finger domain transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24728192,PubMed,10.1128/EC.00075-14,Eukaryot Cell. 2014 Jun;13(6):766-75,amcalvo@niu.edu,,T D Smith 2014,2014,1 gene,Smith-2014-The mtfA Transcription Factor Gene,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4772,PHI:3468,UniProt,A0A075P597,GenBank,AIG00947,,,UK4,pIL-1,,,,,,,294,Pseudomonas fluorescens,,TSS,opportunistic infection,bony fishes,8255,Paralichthys olivaceus (related: japanese flounder),,,,spleen; kidney,virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25465175,PubMed,10.1016/j.vetmic.2014.11.001,Vet Microbiol. 2015 Jan 30;175(1):145-9,lsun@qdio.ac.cn,,Z Zhou 2015,2015,4 genes,Zhou-2015-Pseudomonas fluorescens_ Fur is requ,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4773,PHI:3469,,no data found,,,,,,pCC104,,,,,,,294,Pseudomonas fluorescens,,TSS,opportunistic infection,bony fishes,8255,Paralichthys olivaceus (related: japanese flounder),,,,spleen; kidney,virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25465175,PubMed,10.1016/j.vetmic.2014.11.001,Vet Microbiol. 2015 Jan 30;175(1):145-9,lsun@qdio.ac.cn,,Z Zhou 2015,2015,4 genes,Zhou-2015-Pseudomonas fluorescens_ Fur is requ,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4774,PHI:3470,,no data found,,,,,,pCC148,,,,,,,294,Pseudomonas fluorescens,,TSS,opportunistic infection,bony fishes,8255,Paralichthys olivaceus (related: japanese flounder),,,,spleen; kidney,virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25465175,PubMed,10.1016/j.vetmic.2014.11.001,Vet Microbiol. 2015 Jan 30;175(1):145-9,lsun@qdio.ac.cn,,Z Zhou 2015,2015,4 genes,Zhou-2015-Pseudomonas fluorescens_ Fur is requ,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4775,PHI:3471,UniProt,O68563,GenBank,AAC05680,,,,Fur,,,,,,,294,Pseudomonas fluorescens,,TSS,opportunistic infection,bony fishes,8255,Paralichthys olivaceus (related: japanese flounder),,,,spleen; kidney,global transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25465175,PubMed,10.1016/j.vetmic.2014.11.001,Vet Microbiol. 2015 Jan 30;175(1):145-9,lsun@qdio.ac.cn,"The mutant was impaired in siderophore production and extracellular enzyme activities, (ii) exhibited altered global polarity, (iii) was dramatically reduced in the ability to resist oxidative stress, (iv) showed higher tolerance to manganese, and (v) exhibited significantly reduced cytotoxicity.",Z Zhou 2015,2015,4 genes,Zhou-2015-Pseudomonas fluorescens_ Fur is requ,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4776,PHI:3472,UniProt,Q8X965,GenBank,AAG55075,,,EDL933,TolA,,TW14359deltatolA,,,,,562,Escherichia coli,544404,TW14359,infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,periplasm spanning protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25448467,PubMed,10.1016/j.micpath.2014.10.010,Microb Pathog. 2014 Dec;77:42-52,jkmorgan@mail.usf.edu,,J K Morgan 2014,2014,1 gene,Morgan-2014-The role for TolA in enterohemorrh,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4777,PHI:3473,UniProt,Q97NA4,GenBank,AAK76205,,,TIGR4,arcA,,TIGR4luxdeltaarcA,,,,PHI:3474; PHI:3475; PHI:3476; PHI:3477,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; bronchoalveolar lavage fluid,part of the arginine deiminase system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25538192,PubMed,10.1128/mBio.01858-14,MBio. 2014 Dec 23;5(6). pii: e01858-14,sven.hammerschmidt@uni-greifswald.de,nasopharyngeal lavage and bronchoalveolar lavage fluids,C Schulz 2014,2014,5 genes,Schulz-2014-Regulation of the Arginine Deimina,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4778,PHI:3474,UniProt,P65607,GenBank,AAK76206,,,TIGR4,arcB,,TIGR4luxdeltaarcB,,,,PHI:3473; PHI:3475; PHI:3476; PHI:3477,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; bronchoalveolar lavage fluid,part of the arginine deiminase system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25538192,PubMed,10.1128/mBio.01858-14,MBio. 2014 Dec 23;5(6). pii: e01858-14,sven.hammerschmidt@uni-greifswald.de,nasopharyngeal lavage and bronchoalveolar lavage fluids,C Schulz 2014,2014,5 genes,Schulz-2014-Regulation of the Arginine Deimina,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4779,PHI:3475,UniProt,Q97NA2,GenBank,AAK76207,,,TIGR4,arcC,,TIGR4luxdeltaarcC,,,,PHI:3473; PHI:3474; PHI:3476; PHI:3477,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; bronchoalveolar lavage fluid,part of the arginine deiminase system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25538192,PubMed,10.1128/mBio.01858-14,MBio. 2014 Dec 23;5(6). pii: e01858-14,sven.hammerschmidt@uni-greifswald.de,nasopharyngeal lavage and bronchoalveolar lavage fluids,C Schulz 2014,2014,5 genes,Schulz-2014-Regulation of the Arginine Deimina,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4780,PHI:3476,UniProt,A0A098YX93,GenBank,KGI24034,,,SC_3526,arcD,,TIGR4luxdeltaarcD,,,,PHI:3473; PHI:3474; PHI:3475; PHI:3477,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; bronchoalveolar lavage fluid,part of the arginine deiminase system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25538192,PubMed,10.1128/mBio.01858-14,MBio. 2014 Dec 23;5(6). pii: e01858-14,sven.hammerschmidt@uni-greifswald.de,nasopharyngeal lavage and bronchoalveolar lavage fluids,C Schulz 2014,2014,5 genes,Schulz-2014-Regulation of the Arginine Deimina,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4781,PHI:3477,UniProt,Q97NA0,GenBank,AAK76209,,,TIGR4,arcT,,TIGR4luxdeltaarcT,,,,PHI:3473; PHI:3474; PHI:3475; PHI:3476,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; bronchoalveolar lavage fluid,part of the arginine deiminase system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25538192,PubMed,10.1128/mBio.01858-14,MBio. 2014 Dec 23;5(6). pii: e01858-14,sven.hammerschmidt@uni-greifswald.de,nasopharyngeal lavage and bronchoalveolar lavage fluids,C Schulz 2014,2014,5 genes,Schulz-2014-Regulation of the Arginine Deimina,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4782,PHI:3478,UniProt,G2WXZ2,GenBank,EGY20950,,,VdLs.17,Vdrac1,chromosome 3,,,Vdcla4,UniProt: G2X6S4,,27337,Verticillium dahliae,,Vd8,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf; root,small GTPase,,,,reduced virulence,,,yes,yes,,aberrant,,reduced; aberrant,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,25475370,PubMed,10.1016/j.fgb.2014.11.003,Fungal Genet Biol. 2015 Jan;74:21-31,xywang@njau.edu.cn,,H Tian 2014,2014,2 genes,Tian-2014-Small GTPase Rac1 and its interactio,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4783,PHI:3479,UniProt,G2X6S4,GenBank,EGY14692,,,VdLs.17,Vdcla4,chromosome 4,,,Vdrac1,UniProt: G2WXZ2,,27337,Verticillium dahliae,,Vd8,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,p21-activated kinase,,,,reduced virulence,,,yes,yes,,aberrant,,reduced; aberrant,aberrant,no,,,,,,,gene deletion: full,,,RP,25475370,PubMed,10.1016/j.fgb.2014.11.003,Fungal Genet Biol. 2015 Jan;74:21-31,xywang@njau.edu.cn,,H Tian 2014,2014,2 genes,Tian-2014-Small GTPase Rac1 and its interactio,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4784,PHI:3480,UniProt,D2N983,GenBank,CAQ50581.1,,,ST398,SaTlp1,,,,,,,1280,Staphylococcus aureus,523796,ST398,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,TIR-like domain containing proteins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25538689,PubMed,10.3389/fmicb.2014.00662,Front Microbiol. 2014 Dec 9;5:662,dwerling@rvc.ac.uk,,N J Patterson 2014,2014,2 genes,Patterson-2014-Two TIR-like domain containing,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4785,PHI:3481,,no data found,GenBank,CAQ50581.2,,,ST398,SaTlp2,,,,,,,1280,Staphylococcus aureus,523796,ST398,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,TIR-like domain containing proteins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25538689,PubMed,10.3389/fmicb.2014.00662,Front Microbiol. 2014 Dec 9;5:662,dwerling@rvc.ac.uk,,N J Patterson 2014,2014,2 genes,Patterson-2014-Two TIR-like domain containing,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4786,PHI:3482,UniProt,Q9KSD8,GenBank,AAF94478,,,N16961,VprA,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25538196,PubMed,10.1128/mBio.02283-14,MBio. 2014 Dec 23;5(6),strent@austin.utexas.edu,,C M Herrera 2014,2014,1 gene,Herrera-2014-The Vibrio cholerae VprA-VprB Two,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4787,PHI:3483,UniProt,G4N3H3,GenBank,EHA52648,,,70-15,MoSPC1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,orphan genes,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25506301,PubMed,10.5423/PPJ.OA.08.2014.0072,Plant Pathol J. 2014 Dec;30(4):367-74,yonglee@snu.ac.kr,,A Sadat 2014,2014,4 genes,Sadat-2014-Analysis of in planta Expressed Orp,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4788,PHI:3484,,no data found,,,,,,MoSPC2,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,orphan genes,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25506301,PubMed,10.5423/PPJ.OA.08.2014.0072,Plant Pathol J. 2014 Dec;30(4):367-74,yonglee@snu.ac.kr,,A Sadat 2014,2014,4 genes,Sadat-2014-Analysis of in planta Expressed Orp,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4789,PHI:3485,UniProt,G4MYT5,GenBank,EHA55314,,,70-15,MoSPC3,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,orphan genes,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25506301,PubMed,10.5423/PPJ.OA.08.2014.0072,Plant Pathol J. 2014 Dec;30(4):367-74,yonglee@snu.ac.kr,,A Sadat 2014,2014,4 genes,Sadat-2014-Analysis of in planta Expressed Orp,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4790,PHI:3486,UniProt,G4MZM3,GenBank,EHA55387,,,70-15,MoSPC7,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,orphan genes,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25506301,PubMed,10.5423/PPJ.OA.08.2014.0072,Plant Pathol J. 2014 Dec;30(4):367-74,yonglee@snu.ac.kr,,A Sadat 2014,2014,4 genes,Sadat-2014-Analysis of in planta Expressed Orp,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4791,PHI:3487,UniProt,Q5XEA3,GenBank,AAT86260,,,MGAS10394,AdcR,,,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,adhesin competence repressor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25510500,PubMed,10.1093/nar/gku1304,Nucleic Acids Res. 2015 Jan 9;43(1):418-32,mkumaraswami@houstonmethodist.org,,M Sanson 2014,2014,1 gene,Sanson-2014-Adhesin competence repressor (AdcR,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4792,PHI:3488,UniProt,O84818,GenBank,AAC68408,,,D/UW-3/CX,PmpD,,,,,,,813,Chlamydia trachomatis,272561,D/UW-3/CX,sexually transmitted disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,urogenital system,autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24733093,PubMed,10.1128/IAI.01686-14,Infect Immun. 2014 Jul;82(7):2756-62,hcaldwell@niaid.nih.gov,,L Kari 2014,2014,1 gene,Kari-2014-Chlamydia trachomatis Polymorphic Me,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4793,PHI:3488,UniProt,O84818,GenBank,AAC68408,,,D/UW-3/CX,PmpD,,,,,,,813,Chlamydia trachomatis,272561,D/UW-3/CX,sexually transmitted disease,primates,9541,Macaca fascicularis (related: crab-eating macaque),,,,eye,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24733093,PubMed,10.1128/IAI.01686-14,Infect Immun. 2014 Jul;82(7):2756-62,hcaldwell@niaid.nih.gov,,L Kari 2014,2014,1 gene,Kari-2014-Chlamydia trachomatis Polymorphic Me,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4794,PHI:3489,UniProt,P0CS02,GenBank,AAY85624,,,JEC21,Gmt1,,,,,,PHI:3490,5207,Cryptococcus neoformans,214684,JEC21,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,GDP-mannose transporters,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24747214,PubMed,10.1128/EC.00054-14,Eukaryot Cell. 2014 Jun;13(6):832-42,doering@wustl.edu,"gmt1 gmt2double mutant cells, which are unexpectedly viable, exhibit severe defects in capsule synthesis and protein glycosylation and are avirulent in mouse models of cryptococcosis.",Z A Wang 2014,2014,2 genes,Wang-2014-The dual GDP-mannose transporters of,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4795,PHI:3490,UniProt,P0CS04,GenBank,AAR96298,,,JEC21,Gmt2,,,,,,PHI:3489,5207,Cryptococcus neoformans,214684,JEC21,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,GDP-mannose transporters,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24747214,PubMed,10.1128/EC.00054-14,Eukaryot Cell. 2014 Jun;13(6):832-42,doering@wustl.edu,"gmt1 gmt2double mutant cells, which are unexpectedly viable, exhibit severe defects in capsule synthesis and protein glycosylation and are avirulent in mouse models of cryptococcosis.",Z A Wang 2014,2014,2 genes,Wang-2014-The dual GDP-mannose transporters of,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4796,PHI:3591,UniProt,G3K6H9,GenBank,AEO22192,,,xcp305,rpfF,,,,,,,56454,Xanthomonas hortorum,453602,pv. pelargonii strain 305,bacterial blight (pelargonium),eudicots,4031,Pelargonium x hortorum (related: zonal pelargonium),cv. Anthony,,,stem,encoding the DSF synthase,,,,reduced virulence,,,,yes,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25530086,PubMed,10.1111/mpp.12230,Mol Plant Pathol. 2014 Dec 21,shulam@volcani.agri.gov.il,,V BAREL 2014,2014,2 genes,Barel-2014-Virulence and in planta movement of,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4797,PHI:3592,UniProt,G3K6I0,GenBank,AEO22193,,,xcp305,rpfC,,,,,,,56454,Xanthomonas hortorum,453602,pv. pelargonii strain 305,bacterial blight (pelargonium),eudicots,4031,Pelargonium x hortorum (related: zonal pelargonium),cv. Anthony,,,stem,encoding the histidine sensor kinase of the two-component system RfpC/RpfG,,,,reduced virulence,,,,yes,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25530086,PubMed,10.1111/mpp.12230,Mol Plant Pathol. 2014 Dec 21,shulam@volcani.agri.gov.il,,V BAREL 2014,2014,2 genes,Barel-2014-Virulence and in planta movement of,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4798,PHI:3593,UniProt,B2HSV6,GenBank,ACC41130,,,M,MgtC,,deltamgtC+attB::mgtC,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,intramacrophage growth/mg2+ transport p-type ATPase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25545682,PubMed,10.1371/journal.pone.0116052,PLoS One. 2014 Dec 29;9(12):e116052,anne.blanc-potard@univ-montp1.fr,Phagocytosis by neutrophils is enhanced with the mgtC mutant compared to the wild-type strain.,C Belon 2014,2014,1 gene,Belon-2014-Mycobacterium marinum MgtC Plays a,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4799,PHI:3594,UniProt,H6VMG0,GenBank,AFB74084,,,H99,Ptp2,,MATaptp2delta::NEO,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; brain,protein tyrosine phosphatases,,,HOG pathway,reduced virulence,yes,,,,,,,reduced,,no,fluconazole; ketoconazole; flucytosine; fludioxonil; tert-butyl hydroperoxide (tBOOH); H2O2; NaCl; KCl; hydroxyurea; methyl methanesulfonate; CdSO4,"fluconazole: CHEBI:46081, CAS:86386-73-4; ketoconazole: CHEBI:47519, CAS:65277-42-1; flucytosine: CHEBI:5100; fludioxonil: CHEBI:81763; tert-butyl hydroperoxide (tBOOH): CHEBI:64090; H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; CdSO4: CHEBI:50292",,,,,gene deletion: full; gene complementation,,,RP,24728196,PubMed,10.1128/EC.00069-14,Eukaryot Cell. 2014 Jun;13(6):796-812,ysbahn@yonsei.ac.kr,"Ptp2 suppressed the hyperphosphorylation of Hog1 and was involved in mediating vegetative growth, sexual differentiation, stress responses, antifungal drug resistance, and virulence factor regulation through the negative-feedback loop of the HOG pathway. In contrast, Ptp1 was not essential for Hog1 regulation, despite its Hog1-dependent induction. However, in the absence of Ptp2, Ptp1 served as a complementary PTP to control some stress responses.",K Lee 2014,2014,2 genes,Lee-2014-Distinct and redundant roles of prote,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4800,PHI:3595,UniProt,L7T9I5,GenBank,AGC31491,,,H99,Ptp1,,MATaptp1delta::NEO,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; brain,protein tyrosine phosphatases,,,HOG pathway,unaffected pathogenicity,no,,,,,,,wild type,,no,fluconazole; ketoconazole; flucytosine; fludioxonil; tert-butyl hydroperoxide (tBOOH); H2O2; NaCl; KCl; hydroxyurea; methyl methanesulfonate; CdSO4,"fluconazole: CHEBI:46081, CAS:86386-73-4; ketoconazole: CHEBI:47519, CAS:65277-42-1; flucytosine: CHEBI:5100; fludioxonil: CHEBI:81763; tert-butyl hydroperoxide (tBOOH): CHEBI:64090; H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; CdSO4: CHEBI:50292",,,,,gene deletion: full; gene complementation,,,RP,24728196,PubMed,10.1128/EC.00069-14,Eukaryot Cell. 2014 Jun;13(6):796-812,ysbahn@yonsei.ac.kr,"Ptp2 suppressed the hyperphosphorylation of Hog1 and was involved in mediating vegetative growth, sexual differentiation, stress responses, antifungal drug resistance, and virulence factor regulation through the negative-feedback loop of the HOG pathway. In contrast, Ptp1 was not essential for Hog1 regulation, despite its Hog1-dependent induction. However, in the absence of Ptp2, Ptp1 served as a complementary PTP to control some stress responses.",K Lee 2014,2014,2 genes,Lee-2014-Distinct and redundant roles of prote,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4801,PHI:3594,UniProt,H6VMG0,GenBank,AFB74084,,,H99,Ptp2,,MATaptp2delta::NEO,,,,PHI:3595,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; brain,protein tyrosine phosphatases,,,HOG pathway,reduced virulence,yes,,,,,,,reduced,,no,fluconazole; ketoconazole; flucytosine; fludioxonil; tert-butyl hydroperoxide (tBOOH); H2O2; NaCl; KCl; hydroxyurea; methyl methanesulfonate; CdSO4,"fluconazole: CHEBI:46081, CAS:86386-73-4; ketoconazole: CHEBI:47519, CAS:65277-42-1; flucytosine: CHEBI:5100; fludioxonil: CHEBI:81763; tert-butyl hydroperoxide (tBOOH): CHEBI:64090; H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; CdSO4: CHEBI:50292",,,,,gene deletion: full; gene complementation,,,RP,24728196,PubMed,10.1128/EC.00069-14,Eukaryot Cell. 2014 Jun;13(6):796-812,ysbahn@yonsei.ac.kr,"Ptp2 suppressed the hyperphosphorylation of Hog1 and was involved in mediating vegetative growth, sexual differentiation, stress responses, antifungal drug resistance, and virulence factor regulation through the negative-feedback loop of the HOG pathway. In contrast, Ptp1 was not essential for Hog1 regulation, despite its Hog1-dependent induction. However, in the absence of Ptp2, Ptp1 served as a complementary PTP to control some stress responses.",K Lee 2014,2014,2 genes,Lee-2014-Distinct and redundant roles of prote,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4802,PHI:3595,UniProt,L7T9I5,GenBank,AGC31491,,,H99,Ptp1,,MATaptp2delta::NEO,,,,PHI:3594,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; brain,protein tyrosine phosphatases,,,HOG pathway,reduced virulence,yes,,,,,,,reduced,,no,fluconazole; ketoconazole; flucytosine; fludioxonil; tert-butyl hydroperoxide (tBOOH); H2O2; NaCl; KCl; hydroxyurea; methyl methanesulfonate; CdSO4,"fluconazole: CHEBI:46081, CAS:86386-73-4; ketoconazole: CHEBI:47519, CAS:65277-42-1; flucytosine: CHEBI:5100; fludioxonil: CHEBI:81763; tert-butyl hydroperoxide (tBOOH): CHEBI:64090; H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; CdSO4: CHEBI:50292",,,,,gene deletion: full; gene complementation,,,RP,24728196,PubMed,10.1128/EC.00069-14,Eukaryot Cell. 2014 Jun;13(6):796-812,ysbahn@yonsei.ac.kr,"Ptp2 suppressed the hyperphosphorylation of Hog1 and was involved in mediating vegetative growth, sexual differentiation, stress responses, antifungal drug resistance, and virulence factor regulation through the negative-feedback loop of the HOG pathway. In contrast, Ptp1 was not essential for Hog1 regulation, despite its Hog1-dependent induction. However, in the absence of Ptp2, Ptp1 served as a complementary PTP to control some stress responses.",K Lee 2014,2014,2 genes,Lee-2014-Distinct and redundant roles of prote,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4803,PHI:3596,UniProt,A1YKW7,GenBank,ABK58601,,,269-492,RtxA,,pUC19-rtxA::kan,,,,,504,Kingella kingae,1150867,PYKK081,skeletal disease (children); infective endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart; lung; kidney; thymus; spleen; hip joint; bone marrow,RTX toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24664507,PubMed,10.1128/IAI.01636-14,Infect Immun. 2014 Jun;82(6):2318-28,balashnv@sdm.rutgers.edu,The toxin contributes to WBC depletion. Tibia bone marrow,D W Chang,2014,1 gene,Chang-2014-RTX-toxin plays a key role in Kinge,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4804,PHI:3597,UniProt,P0AC26,GenBank,CAA32418,,,K-12,NirC,,SCI-07deltanirC,,,,,562,Escherichia coli,1144302,APEC strain SCI-07,colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,,nitrite transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25487442,PubMed,10.1016/j.vetmic.2014.11.015,Vet Microbiol. 2015 Jan 30;175(1):123-31,wds@unicamp.br,"The final cumulative mortalities caused by mutant and wild-type (WT) were similar; while the DnirC caused a gradual increase in the mortality rate during the seven days recorded, the WT caused mortality up to 24 h post-infection (hpi).",J B de Paiva 2015,2015,1 gene,Paiva-2015-Influence of the major nitrite tran,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4805,PHI:3598,,no data found,,,,,,CSPG4,,,,TcdB,UniProt: P18177,,1496,Clostridioides difficile,,,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,cellular receptor for clostridium difficile toxin B,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25547119,PubMed,10.1038/cr.2014.169,Cell Res. 2015 Feb;25(2):157-68,wswei@pku.edu.cn,complete loss of CSPG4/NG2 decreased TcdB-triggered interleukin-8 induction in mice without significantly affecting animal mortality. Pathogen formerly called Clostridium difficile,P Yuan 2014,2014,1 gene,Yuan-2014-Chondroitin sulfate proteoglycan 4 f,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4806,PHI:3599,UniProt,Q83CA1,GenBank,AAO90736,,,RSA 493,PmrA,,,,,,,777,Coxiella burnetii,227377,Nine Mile Phase I,Q fever,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line; THP-1 cell line,,,THP-1 cell,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24610709,PubMed,10.1128/JB.01532-14,J Bacteriol. 2014 Jun;196(11):1925-40,rheinzen@niaid.nih.gov,C. burnetii pmrAexhibited severe intracellular growth defects that coincided with failed secretion of effector proteins.,P A Beare 2014,2014,1 gene,Beare-2014-Essential role for the response reg,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4807,PHI:3599,UniProt,Q83CA1,GenBank,AAO90736,,,RSA 493,PmrA,,,,,,,777,Coxiella burnetii,227377,Nine Mile Phase I,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocytic leukemia cell line,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24610709,PubMed,10.1128/JB.01532-14,J Bacteriol. 2014 Jun;196(11):1925-40,rheinzen@niaid.nih.gov,C. burnetii pmrAexhibited severe intracellular growth defects that coincided with failed secretion of effector proteins.,P A Beare 2014,2014,1 gene,Beare-2014-Essential role for the response reg,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4808,PHI:3600,UniProt,Q8TG07,GenBank,AAM16160,,,,plb1,,,,,,,5478,Candida glabrata,,BG2,peritonitis,rodents,10090,Mus musculus (related: house mouse),ICR,,,abdomen; spleen; liver; pancreas,"phospholipase B (PLB) is a secretory enzyme that hydrolyzes phospholipids, plays key roles in cellular processes like signal transduction and membrane modeling, and mediates microbial virulence by disrupting host cell membranes.",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24799629,PubMed,10.1128/IAI.00062-14,Infect Immun. 2014 Jul;82(7):3015-22,cjc76@pitt.edu,,S Cheng 2014,2014,2 genes,Cheng-2014-Candida glabrata intra-abdominal ca,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4809,PHI:3601,UniProt,Q8TG06,GenBank,AAM19335,,,,plb2,,,,,,,5478,Candida glabrata,,BG2,peritonitis,rodents,10090,Mus musculus (related: house mouse),ICR,,,abdomen; spleen; liver; pancreas,"phospholipase B (PLB) is a secretory enzyme that hydrolyzes phospholipids, plays key roles in cellular processes like signal transduction and membrane modeling, and mediates microbial virulence by disrupting host cell membranes.",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24799629,PubMed,10.1128/IAI.00062-14,Infect Immun. 2014 Jul;82(7):3015-22,cjc76@pitt.edu,,S Cheng 2014,2014,2 genes,Cheng-2014-Candida glabrata intra-abdominal ca,Batch044B,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4810,PHI:3602,UniProt,B2HSU5,GenBank,ACC41119,,,M,ESX-5,,,,,,,1781,Mycobacterium marinum,1131442,E11,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,mycobacterial type VII protein secretion system responsible for transport of numerous PE and PPE proteins.,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,22256857,PubMed,10.1111/j.1462-5822.2012.01755.x,Cell Microbiol. 2012 May;14(5):728-39,a.vandersar@vumc.nl,,E M Weerdenburg 2012,2012,1 gene,Weerdenburg-2012-ESX-5-deficient Mycobacterium,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4811,PHI:3602,UniProt,B2HSU5,GenBank,ACC41119,,,M,ESX-5,,,,,,,1781,Mycobacterium marinum,1131442,E11,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,adult,mycobacterial type VII protein secretion system responsible for transport of numerous PE and PPE proteins.,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,22256857,PubMed,10.1111/j.1462-5822.2012.01755.x,Cell Microbiol. 2012 May;14(5):728-39,a.vandersar@vumc.nl,,E M Weerdenburg 2012,2012,1 gene,Weerdenburg-2012-ESX-5-deficient Mycobacterium,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4812,PHI:3603,UniProt,H8H8R6,GenBank,AFC65804,,,MGAS15252,CcpA,,,,,,,1314,Streptococcus pyogenes,293653,MGAS5005,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,global mediator of carbon catabolite repression,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,18490461,PubMed,10.1128/IAI.00343-08,Infect Immun. 2008 Aug;76(8):3451-63,kmciver@umd.edu,,T L Kinkel 2008,2008,1 gene,Kinkel-2008-CcpA-mediated repression of strept,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4813,PHI:3604,UniProt,Q54970,GenBank,AAB40976,,,R6x,spxB,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,pyruvate oxidase gene,,,,increased virulence (hypervirulence),,,,yes,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24443543,PubMed,10.1093/infdis/jiu038,J Infect Dis. 2014 Jul 1;210(1):4-13. Epub 2014 Jan 16,birgitta.henriques@ki.se,"spxB mutants were considerably more virulent in wild-type mice, less susceptible to early host clearance than wild-type strains after intravenous infection, but impaired in colonization.",A Syk 2014,2014,1 gene,Syk-2014-Emergence of hypervirulent mutants re,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4814,PHI:3605,UniProt,F7WKX4,GenBank,AEJ48086,,,CCDC5079,fadB4,,,,,,,1773,Mycobacterium tuberculosis,,Mt103,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,NADPH quinone oxidoreductase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,18068389,PubMed,10.1016/j.micinf.2007.10.001,Microbes Infect. 2008 Jan;10(1):38-44. Epub 2007 Oct 7,jamiet@infdis.usyd.edu.au,DfadB4 demonstrated an increased replication at early time-points post-infection compared to the growth of wild-typeM. Tuberculosis.,G M Scandurra 2008,2008,1 gene,Scandurra-2008-Inactivation of the Mycobacteri,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4815,PHI:3607,UniProt,K7NCV2,GenBank,AET13879,,,Fl1,sidN,,,,,,,35717,Epichloe festucae,877507,Fl1,,monocots,4522,Lolium perenne (related: perennial ryegrass),cv. Nui,,,leaf,non-ribosomal peptide synthetase gene (sidN) encoding a siderophore synthetase,,,,increased virulence (hypervirulence),,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,23658520,PubMed,10.1371/journal.ppat.1003332,PLoS Pathog. 2013;9(5):e1003332,Linda.Johnson@agresearch.co.nz,"Lack of SidN alters iron homeostasis of the symbiotum, changing it from mutually beneficial to antagonistic.",L J Johnson 2013,2013,1 gene,Johnson-2013-An extracellular siderophore is r,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4816,PHI:3608,UniProt,Q6VBI9,GenBank,AAQ82692,,,,EPA2,chromosome E,PPGK::FRT::TRP1::FRT::hph epa2delta::FLP1 (EPA2ORF was replaced with the S. cerevisiae FLP1 gene encoding the Flp1 site-specific recombinase in the BG625 background).,,,,,5478,Candida glabrata,,BG2,peritonitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen,adhesin,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,25586543,PubMed,10.1007/s00294-015-0473-2,Curr Genet. 2015 Jan 14,cano@ipicyt.edu.mx,EPA2 gene is induced specifically in vitro in the presence of oxidative stress generated by H2O2,J Juárez-Cepeda 2015,2015,1 gene,Juarez-Cepeda-2015-The EPA2 adhesin encoding g,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4817,PHI:3609,UniProt,T2K373,GenBank,CCW73000,,,DT104,sciS,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,intracellular multiplication,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,15972528,PubMed,10.1128/IAI.73.7.4338-4345.2005,Infect Immun. 2005 Jul;73(7):4338-45,parsonsd@ohsu.edu,,D . Parsons 2005,2005,1 gene,"Parsons-2005-sciS, an icmF homolog in Salmonel",Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4818,PHI:3610,UniProt,Q6KD45,GenBank,ACJ63516,,,APEC O103,iucD,,E058deltaiucD,,,,,562,Escherichia coli,,E058,colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen; lung; kidney; heart,aerobactin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,25582605,PubMed,10.1016/j.meegid.2014.12.038,Infect Genet Evol. 2015 Mar;30:267-77,gsong@yzu.edu.cn,,Q Gao 2015,2015,2 genes,Gao-2015-The avian pathogenic Escherichia coli,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4819,PHI:3611,UniProt,B1LE77,GenBank,ACB16832,,,SMS-3-5,iutA,,E058deltaiucDdeltaiutA,,,,PHI:3610,562,Escherichia coli,,E058,colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen; lung; kidney; heart,aerobactin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,25582605,PubMed,10.1016/j.meegid.2014.12.038,Infect Genet Evol. 2015 Mar;30:267-77,gsong@yzu.edu.cn,,Q Gao 2015,2015,2 genes,Gao-2015-The avian pathogenic Escherichia coli,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4820,PHI:3610,UniProt,Q6KD45,GenBank,ACJ63516,,,APEC O103,iucD,,E058deltaiucD,,,,PHI:3611,562,Escherichia coli,,E058,colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen; lung; kidney; heart,aerobactin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,25582605,PubMed,10.1016/j.meegid.2014.12.038,Infect Genet Evol. 2015 Mar;30:267-77,gsong@yzu.edu.cn,,Q Gao 2015,2015,2 genes,Gao-2015-The avian pathogenic Escherichia coli,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4821,PHI:3612,,no data found,,,,,,stf3,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; lung,sulfotransferase,,,sulfate assimilation pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,16537518,PubMed,10.1073/pnas.0510861103,Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4258-63,crb@berkeley.edu,,J D Mougous 2006,2006,1 gene,Mougous-2006-A sulfated metabolite produced by,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4822,PHI:3613,UniProt,N0DU70,GenBank,BAN17453,,,Fl1,ProA,,,,,,,35717,Epichloe festucae,696363,E2368,,monocots,4522,Lolium perenne (related: perennial ryegrass),,,,leaf,transcription factor with a Zn(II)2Cys6(C6-zinc) helps in symbiotic relationship,,,ROS signalling pathway,increased virulence (hypervirulence),,,,,,increased,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23998652,PubMed,10.1111/mmi.12385,Mol Microbiol. 2013 Nov;90(3):551-68,d.b.scott@massey.ac.nz,"ProA is a key regulator of in planta specific growth of E. festucae, and therefore crucial for maintaining a mutualistic symbiotic interaction",A Tanaka 2013,2013,1 gene,"Tanaka-2013-ProA, a transcriptional regulator",Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4823,PHI:3614,UniProt,P9WMF9,GenBank,AAD17452,,,H37Rv,dosR (devR),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4824,PHI:3615,UniProt,O69730,GenBank,CAA67749,,,H37Rv,tcrX,,,,,,PHI:3616,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4825,PHI:3616,UniProt,O69729,GenBank,CCP46591,,,H37Rv,tcrY,,,,,,PHI:3615,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4826,PHI:3617,UniProt,P96368,GenBank,AFN48924,,,H37Rv,trcS,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4827,PHI:3618,UniProt,P9WGL3,GenBank,CCP43778,,,H37Rv,kdpD,,,,,,PHI:3619,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4828,PHI:3619,UniProt,P9WGN1,GenBank,CCP43777,,,H37Rv,kdpE,,,,,,PHI:3618,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4829,PHI:3620,UniProt,P9WGM5,GenBank,CCP43592,,,H37Rv,narL,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,lung; liver; spleen,two-component regulatory systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4830,PHI:3621,UniProt,P9WGL5,GenBank,CCP46036,,,H37Rv,Rv3220c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,lung; liver; spleen,two-component regulatory systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4831,PHI:3614,UniProt,P9WMF9,GenBank,AAD17452,,,H37Rv,devR,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),DBA/2,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4832,PHI:3615,UniProt,O69730,GenBank,CAA67749,,,H37Rv,tcrX,,,,,,PHI:3616,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),DBA/2,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4833,PHI:3616,UniProt,O69729,GenBank,CCP46591,,,H37Rv,tcrY,,,,,,PHI:3615,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),DBA/2,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4834,PHI:3617,UniProt,P96368,GenBank,AFN48924,,,H37Rv,trcS,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),DBA/2,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4835,PHI:3618,UniProt,P9WGL3,GenBank,CCP43778,,,H37Rv,kdpD,,,,,,PHI:3619,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),DBA/2,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4836,PHI:3619,UniProt,P9WGN1,GenBank,CCP43777,,,H37Rv,kdpE,,,,,,PHI:3618,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),DBA/2,,,lung; liver; spleen,two-component regulatory systems,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4837,PHI:3620,UniProt,P9WGM5,GenBank,CCP43592,,,H37Rv,narL,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),DBA/2,,,lung; liver; spleen,two-component regulatory systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4838,PHI:3621,UniProt,P9WGL5,GenBank,CCP46036,,,H37Rv,Rv3220c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),DBA/2,,,lung; liver; spleen,two-component regulatory systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12595424,PubMed,10.1128/IAI.71.3.1134-1140.2003,Infect Immun. 2003 Mar;71(3):1134-40,nstoker@rvc.ac.uk,,T Parish 2003,2003,8 genes,Parish-2003-Deletion of two-component regulato,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4839,PHI:3622,UniProt,Q79FZ9,GenBank,AFN48018,,,H37Rv,mce1,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,"encode proteins with hydrophobic stretchesat their N terminus, indicative of surface-exposed proteins",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,14663145,PubMed,10.1073/pnas.2433882100,Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15918-23,lwriley@uclink4.berkeley.edu,,N Shimono 2003,2003,1 gene,Shimono-2003-Hypervirulent mutant of Mycobacte,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4840,PHI:3623,UniProt,A0JC80,GenBank,BAF36499,,,Fl1,RacA,,,,,,,35717,Epichloe festucae,877507,Fl1,,monocots,4522,Lolium perenne (related: perennial ryegrass),,,,leaf,regulates production of ROS to maintain a symbiotic interaction withthe perennial rye grass.,,,,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,18399936,PubMed,10.1111/j.1365-2958.2008.06217.x,Mol Microbiol. 2008 Jun;68(5):1165-78,d.b.scott@massey.ac.nz,,A Tanaka 2008,2008,1 gene,Tanaka-2008-NoxA activation by the small GTPas,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4841,PHI:3624,UniProt,P9WI71,GenBank,CCP44022,,,H37Rv,pknH,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,serine/threonine kinase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,sodium nitrite,sodium nitrite: CHEBI:78870,,,,,gene disruption; gene complementation,,,RP,16077122,PubMed,10.1128/JB.187.16.5751-5760.2005,J Bacteriol. 2005 Aug;187(16):5751-60,yossi@interchange.ubc.ca,,K G Papavinasasundaram 2005,2005,2 genes,Papavinasasunda-2005-Deletion of the Mycobacte,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4842,PHI:3625,UniProt,P9WI77,GenBank,CCP44509,,,H37Rv,pknE,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,16077122,PubMed,10.1128/JB.187.16.5751-5760.2005,J Bacteriol. 2005 Aug;187(16):5751-60,yossi@interchange.ubc.ca,,K G Papavinasasundaram 2005,2005,2 genes,Papavinasasunda-2005-Deletion of the Mycobacte,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4843,PHI:3626,UniProt,Q5ALN4,GenBank,EAL03698,,,SC5314,OPI1,,opi1::CaNAT1-FLP,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,whole body,"regulates expression of theSAP2protease, which is required for rat vaginal infections.",,,,unaffected pathogenicity,,,,,,,,increased; aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,25602740,PubMed,10.1371/journal.pone.0116974,PLoS One. 2015 Jan 20;10(1):e0116974,treynol6@utk.edu,"Although, the mutant does not affect virulence in a mouse model of systemic infection, it does affect virulence in a rat model of vaginitis.",Y Chen 2015,2015,1 gene,Chen-2015-Candida albicans OPI1 Regulates Fila,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4844,PHI:3626,UniProt,Q5ALN4,GenBank,EAL03698,,,SC5314,OPI1,,opi1::CaNAT1-FLP,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10114,Rattus (related: rat),Wistar,,,vagina,"regulates expression of theSAP2protease, which is required for rat vaginal infections.",,,,increased virulence (hypervirulence),,,,,,,,increased; aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,25602740,PubMed,10.1371/journal.pone.0116974,PLoS One. 2015 Jan 20;10(1):e0116974,treynol6@utk.edu,"Although, the mutant does not affect virulence in a mouse model of systemic infection, it does affect virulence in a rat model of vaginitis.",Y Chen 2015,2015,1 gene,Chen-2015-Candida albicans OPI1 Regulates Fila,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4845,PHI:3627,UniProt,P9WNC3,GenBank,CCP45727,,,H37Rv,Rv2924c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,formamidopyrimidine-DNA-glycosylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4846,PHI:3628,UniProt,O05853,GenBank,AFN51214,,,H37Rv,Rv3213c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,possible role in chromosome segregation,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4847,PHI:3629,UniProt,P95200,GenBank,AFN48246,,,H37Rv,Rv0392c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,possible dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4848,PHI:3630,UniProt,L7N655,GenBank,AFN50433,,,H37Rv,PepN,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,probable aminopeptidase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4849,PHI:3631,UniProt,O06806,GenBank,AFN49702,,,H37Rv,Rv1773c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,transcriptional regulator (IclR family),,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,Rv2467,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4850,PHI:3632,UniProt,P9WIP7,GenBank,CCP46420,,,H37Rv,Rv3597c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,Lsr2 homologue,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4851,PHI:3633,UniProt,Q6MX39,GenBank,AFN48327,,,H37Rv,UmaA1,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,unknown mycolic acid methyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4852,PHI:3634,UniProt,O05877,GenBank,ABQ58103,,,H37Rv,Rv3232c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,"unknown, possible transcriptional regulator",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4853,PHI:3635,UniProt,P9WG11,GenBank,CAA53045,,,H37Rv,Rv0930,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,PstA component of phosphate uptake,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4854,PHI:3636,UniProt,P9WIN1,GenBank,AAC43638,,,H37Rv,Rv2702,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,polyphosphate glucokinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4855,PHI:3637,UniProt,O05895,GenBank,AFN51257,,,H37Rv,alkB (Rv3252c),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,transmembrane alkane-1-monooxygenase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4856,PHI:3638,UniProt,O06567,GenBank,AFN49013,,,H37Rv,Rv1115,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,export protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4857,PHI:3639,UniProt,P9WM61,GenBank,CCP42829,,,H37Rv,Rv0104,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4858,PHI:3640,UniProt,P9WKN9,GenBank,CCP43690,,,H37Rv,Rv0942,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4859,PHI:3641,UniProt,L0T8G6,GenBank,CCP43797,,,H37Rv,Rv1046c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4860,PHI:3642,UniProt,P9WKZ3,GenBank,CCP46226,,,H37Rv,Rv3404c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4861,PHI:3643,UniProt,P9WM35,GenBank,CCP44046,,,H37Rv,Rv1290c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4862,PHI:3644,UniProt,O07741,GenBank,AFN49822,,,H37Rv,Rv1891c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,12368431,PubMed,10.1099/00221287-148-10-2975,Microbiology. 2002 Oct;148(Pt 10):2975-86,kd9430@gsk.com,,R A McAdam 2002,2002,18 genes,McAdam-2002-Characterization of a Mycobacteriu,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4863,PHI:3645,UniProt,Q8YFR7,GenBank,AAL52634,,,16M,bpdA,,,,,,,29459,Brucella melitensis,224914,16M,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),IRF-1<-/->,,,spleen,cyclic-di-GMP-specific phosphodiesterase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21856843,PubMed,10.1128/JB.00428-11,J Bacteriol. 2011 Oct;193(20):5683-91,Splitter@svm.vetmed.wisc.edu,,E Petersen 2011,2011,3 genes,Petersen-2011-Brucella melitensis cyclic di-GM,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4864,PHI:3646,UniProt,Q8YFS2,GenBank,AAL52629,,,16M,bpdB,,,,,,,29459,Brucella melitensis,224914,16M,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),IRF-1<-/->,,,spleen,cyclic-di-GMP-specific phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21856843,PubMed,10.1128/JB.00428-11,J Bacteriol. 2011 Oct;193(20):5683-91,Splitter@svm.vetmed.wisc.edu,,E Petersen 2011,2011,3 genes,Petersen-2011-Brucella melitensis cyclic di-GM,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4865,PHI:3647,UniProt,Q8YFK0,GenBank,AAL52701,,,16M,cgsB,,,,,,,29459,Brucella melitensis,224914,16M,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),IRF-1<-/->,,,spleen,cyclic-di-GMP-specific phosphodiesterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,21856843,PubMed,10.1128/JB.00428-11,J Bacteriol. 2011 Oct;193(20):5683-91,Splitter@svm.vetmed.wisc.edu,,E Petersen 2011,2011,3 genes,Petersen-2011-Brucella melitensis cyclic di-GM,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4866,PHI:3648,UniProt,A7DV80,GenBank,CAL25382,,,CECT4999=R99,vep20,,,,,,,672,Vibrio vulnificus,196600,YJ016,vibriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney; spleen,transferrin receptors,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25630302,PubMed,10.1111/1462-2920.12782,Environ Microbiol. 2015 Jan 29,carmen.amaro@uv.es,,D Pajuelo 2015,2015,3 genes,Pajuelo-2015-Novel host-specific iron acquisit,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4867,PHI:3648,UniProt,A7DV80,GenBank,CAL25382,,,CECT4999=R99,vep20,,,,,,,672,Vibrio vulnificus,196600,YJ016,vibriosis,bony fishes,7936,Anguilla anguilla (related: european eel),,,,liver; kidney; spleen; gill,transferrin receptors,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25630302,PubMed,10.1111/1462-2920.12782,Environ Microbiol. 2015 Jan 29,carmen.amaro@uv.es,,D Pajuelo 2015,2015,3 genes,Pajuelo-2015-Novel host-specific iron acquisit,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4868,PHI:3648,UniProt,A7DV80,GenBank,CAL25382,,,CECT4999=R99,vep20,,,,,,PHI:3649; PHI:3650,672,Vibrio vulnificus,196600,YJ016,vibriosis,bony fishes,7936,Anguilla anguilla (related: european eel),,,,liver; kidney; spleen; gill,transferrin receptors,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25630302,PubMed,10.1111/1462-2920.12782,Environ Microbiol. 2015 Jan 29,carmen.amaro@uv.es,,D Pajuelo 2015,2015,3 genes,Pajuelo-2015-Novel host-specific iron acquisit,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4869,PHI:3649,UniProt,Q9L9Z9,GenBank,AF156494_1,,,MO6-24,vuuA,,,,,,PHI:3648; PHI:3650,672,Vibrio vulnificus,196600,YJ016,vibriosis,bony fishes,7936,Anguilla anguilla (related: european eel),,,,liver; kidney; spleen; gill,vulnibactin outer membrane receptor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25630302,PubMed,10.1111/1462-2920.12782,Environ Microbiol. 2015 Jan 29,carmen.amaro@uv.es,,D Pajuelo 2015,2015,3 genes,Pajuelo-2015-Novel host-specific iron acquisit,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4870,PHI:3650,UniProt,Q8GRB8,GenBank,BAC15762,,,L-180,hupA,,,,,,PHI:3648; PHI:3649,672,Vibrio vulnificus,196600,YJ016,vibriosis,bony fishes,7936,Anguilla anguilla (related: european eel),,,,liver; kidney; spleen; gill,receptor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25630302,PubMed,10.1111/1462-2920.12782,Environ Microbiol. 2015 Jan 29,carmen.amaro@uv.es,,D Pajuelo 2015,2015,3 genes,Pajuelo-2015-Novel host-specific iron acquisit,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4871,PHI:3651,UniProt,H8M532,GenBank,AFD58524,,,798,pcgL,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,liver; spleen,D-Ala-D-Ala dipeptidase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,12180921,PubMed,10.1046/j.1365-2958.2002.03070.x,Mol Microbiol. 2002 Aug;45(4):1019-27,groisman@borcim.wustl.edu,The pcgL mutant was unable to grow on D-Ala-D-Ala as sole carbon source and was defective for survival in nutrient-poor conditions.,C Mouslim 2002,2002,1 gene,Mouslim-2002-Conflicting needs for a Salmonell,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4872,PHI:3651,UniProt,H8M532,GenBank,AFD58524,,,798,pcgL,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,liver; spleen,D-Ala-D-Ala dipeptidase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,12180921,PubMed,10.1046/j.1365-2958.2002.03070.x,Mol Microbiol. 2002 Aug;45(4):1019-27,groisman@borcim.wustl.edu,The pcgL mutant was unable to grow on D-Ala-D-Ala as sole carbon source and was defective for survival in nutrient-poor conditions.,C Mouslim 2002,2002,1 gene,Mouslim-2002-Conflicting needs for a Salmonell,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4873,PHI:3652,UniProt,Q71VZ1,GenBank,AAT05525,,,F2365,gshF,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver,glutathione biosynthesis,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25567281,PubMed,10.1038/nature14029,Nature. 2015 Jan 8;517(7533):170-3,portnoy@berkeley.edu,"The DgshFwas not attenuated during infection due to a general loss of fitness, but rather, due to a dysregulation of virulence genes.",M L Reniere 2015,2015,2 genes,Reniere-2015-Glutathione activates virulence g,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4874,PHI:3653,UniProt,Q4TVQ0,GenBank,AAY54617,,,10403S,PrfA,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver,listeriolysin positive regulatory factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25567281,PubMed,10.1038/nature14029,Nature. 2015 Jan 8;517(7533):170-3,portnoy@berkeley.edu,"The DgshFwas not attenuated during infection due to a general loss of fitness, but rather, due to a dysregulation of virulence genes.",M L Reniere 2015,2015,2 genes,Reniere-2015-Glutathione activates virulence g,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4875,PHI:3652,UniProt,Q71VZ1,GenBank,AAT05525,,,F2365,gshF,,,,,,PHI:3653,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver,glutathione biosynthesis,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25567281,PubMed,10.1038/nature14029,Nature. 2015 Jan 8;517(7533):170-3,portnoy@berkeley.edu,"The DgshFwas not attenuated during infection due to a general loss of fitness, but rather, due to a dysregulation of virulence genes.",M L Reniere 2015,2015,2 genes,Reniere-2015-Glutathione activates virulence g,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4876,PHI:3653,UniProt,Q4TVQ0,GenBank,AAY54617,,,10403S,PrfA,,,,,,PHI:3652,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver,listeriolysin positive regulatory factor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25567281,PubMed,10.1038/nature14029,Nature. 2015 Jan 8;517(7533):170-3,portnoy@berkeley.edu,"The DgshFwas not attenuated during infection due to a general loss of fitness, but rather, due to a dysregulation of virulence genes.",M L Reniere 2015,2015,2 genes,Reniere-2015-Glutathione activates virulence g,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4877,PHI:3654,UniProt,Q5AKZ4,GenBank,EAL03420,,,SC5314,Mcu1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen,N-acetylglucosamine (GlcNAc) utilization,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,25626172,PubMed,10.1016/j.fgb.2015.01.006,Fungal Genet Biol. 2015 Jan 24. pii: S1087-1845(15)00009-2,huanggh@im.ac.cn,Deletion ofMCU1also caused defects in utilizing non-fermentable carbon sources and amino acids,G Guan 2015,2015,1 gene,Guan-2015-The mitochondrial protein Mcu1 plays,Batch045A,2015-02-01,MC,,,,,,,,,,,,,
,,Record 4878,PHI:3655,UniProt,C1IL67,GenBank,ACF15629,,,,rssC,,,,,,,615,Serratia marcescens,,CH-1,nosocomial infection,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,larynx,acyltransferase,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,,,,,,,gene disruption,,,RP,18445479,PubMed,10.1016/j.bbrc.2008.04.109,Biochem Biophys Res Commun. 2008 Jul 4;371(3):462-7,pcsoo@saturn.yzu.edu.tw,"The rssCknock-out mutantS. marcescens PC105 showed aberrant and hypervirulent phenotypes including precocious swarming behavior, reduced cell attachment ability and increase in swimming motility, flagellin synthesis, capsular polysaccharide (CPS) production, hemolysin activity, and cytotoxicity activity.",P Soo 2008,2008,1 gene,Soo-2008-A potential acyltransferase regulates,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4879,PHI:3656,,no data found,GenBank,KJ831045,,,,UvSUN2,,,,,,,1159556,Ustilaginoidea virens,,P1,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Liangyoupeijiu,,,leaf,SUN family protein,,,,loss of pathogenicity,,,,,,aberrant,,reduced; aberrant,reduced,no,H2O2; NaCl; Congo red; SDS,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene disruption,,,RP,25636735,PubMed,10.1016/j.fgb.2015.01.004,Fungal Genet Biol. 2015 Jan 28;76C:10-19,liuyf@jaas.ac.cn,The mutants are more resistant to stresses.,M Yu 2015,2015,1 gene,Yu-2015-Identification of pathogenicity-relate,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4880,PHI:3657,UniProt,I1RIV2,EMBL,FGRAMPH1_01T13607,,,CS3005,NPS6,,nps1delta:::hygB; nps2delta:::nptII; nps6delta:::BDS,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spike,peptide synthetase,,,,reduced virulence,,,,,,,wild type,,,no,H2O2; KO2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,25628608,PubMed,10.3389/fmicb.2014.00759,Front Microbiol. 2015 Jan 12;5:759,bgt1@cornell.edu,"NPS6 is sensitive to stresses, however, NPS1 and NPS2 are not.",S Oide 2014,2014,2 genes,Oide-2014-Individual and combined roles of mal,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4881,PHI:3658,UniProt,I1RN14,EMBL,FGRAMPH1_01T17751,,,CS3005,NPS2,,nps1delta:::hygB; nps2delta:::nptII; nps6delta:::BDS,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spike,peptide synthetase,,,,unaffected pathogenicity,,,,,,,reduced,,,no,H2O2; KO2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,25628608,PubMed,10.3389/fmicb.2014.00759,Front Microbiol. 2015 Jan 12;5:759,bgt1@cornell.edu,"NPS6 is sensitive to stresses, however, NPS1 and NPS2 are not.",S Oide 2014,2014,2 genes,Oide-2014-Individual and combined roles of mal,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4882,PHI:3659,UniProt,I1S2M7,EMBL,FGRAMPH1_01T21053,,,CS3005,NPS1,,nps1delta:::hygB; nps2delta:::nptII; nps6delta:::BDS,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spike,peptide synthetase,,,,unaffected pathogenicity,,,,,,,wild type,,,no,H2O2; KO2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,25628608,PubMed,10.3389/fmicb.2014.00759,Front Microbiol. 2015 Jan 12;5:759,bgt1@cornell.edu,"NPS6 is sensitive to stresses, however, NPS1 and NPS2 are not.",S Oide 2014,2014,2 genes,Oide-2014-Individual and combined roles of mal,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4883,PHI:3657,UniProt,I1RIV2,EMBL,FGRAMPH1_01T13607,,,CS3005,NPS6,,nps1delta:::hygB; nps2delta:::nptII; nps6delta:::BDS,,,,PHI:3658; PHI:3659,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spike,peptide synthetase,,,,reduced virulence,,,,,,,reduced,,,no,H2O2; KO2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,25628608,PubMed,10.3389/fmicb.2014.00759,Front Microbiol. 2015 Jan 12;5:759,bgt1@cornell.edu,"NPS6 is sensitive to stresses, however, NPS1 and NPS2 are not.",S Oide 2014,2014,2 genes,Oide-2014-Individual and combined roles of mal,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4884,PHI:3658,UniProt,I1RN14,EMBL,FGRAMPH1_01T17751,,,CS3005,NPS2,,nps1delta:::hygB; nps2delta:::nptII; nps6delta:::BDS,,,,PHI:3657; PHI:3659,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spike,peptide synthetase,,,,reduced virulence,,,,,,,reduced,,,no,H2O2; KO2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,25628608,PubMed,10.3389/fmicb.2014.00759,Front Microbiol. 2015 Jan 12;5:759,bgt1@cornell.edu,"NPS6 is sensitive to stresses, however, NPS1 and NPS2 are not.",S Oide 2014,2014,2 genes,Oide-2014-Individual and combined roles of mal,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4885,PHI:3659,UniProt,I1S2M7,EMBL,FGRAMPH1_01T21053,,,CS3005,NPS1,,nps1delta:::hygB; nps2delta:::nptII; nps6delta:::BDS,,,,PHI:3657; PHI:3658,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spike,peptide synthetase,,,,reduced virulence,,,,,,,reduced,,,no,H2O2; KO2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,25628608,PubMed,10.3389/fmicb.2014.00759,Front Microbiol. 2015 Jan 12;5:759,bgt1@cornell.edu,"NPS6 is sensitive to stresses, however, NPS1 and NPS2 are not.",S Oide 2014,2014,2 genes,Oide-2014-Individual and combined roles of mal,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4886,PHI:3657,UniProt,I1RIV2,EMBL,FGRAMPH1_01T13607,,,CS3005,NPS6,,nps1delta:::hygB; nps2delta:::nptII; nps6delta:::BDS,,,,PHI:3658,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spike,peptide synthetase,,,,reduced virulence,,,,,,,reduced,,,no,H2O2; KO2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,25628608,PubMed,10.3389/fmicb.2014.00759,Front Microbiol. 2015 Jan 12;5:759,bgt1@cornell.edu,"NPS6 is sensitive to stresses, however, NPS1 and NPS2 are not.",S Oide 2014,2014,2 genes,Oide-2014-Individual and combined roles of mal,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4887,PHI:3658,UniProt,I1RN14,EMBL,FGRAMPH1_01T17751,,,CS3005,NPS2,,nps1delta:::hygB; nps2delta:::nptII; nps6delta:::BDS,,,,PHI:3657,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spike,peptide synthetase,,,,reduced virulence,,,,,,,reduced,,,no,H2O2; KO2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,25628608,PubMed,10.3389/fmicb.2014.00759,Front Microbiol. 2015 Jan 12;5:759,bgt1@cornell.edu,"NPS6 is sensitive to stresses, however, NPS1 and NPS2 are not.",S Oide 2014,2014,2 genes,Oide-2014-Individual and combined roles of mal,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4888,PHI:3659,UniProt,Q879S6,GenBank,AAO29937,,,Temecula1,HxfA (PD_2118) (pspA),,PD2118::EZ::TN<Kan-2>Tnp,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,"HL secreted protein, HxfA",,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,16134898,PubMed,10.1094/MPMI-18-0856,Mol Plant Microbe Interact. 2005 Aug;18(8):856-68,bckirkpatrick@ucdavis.edu,,M R Guilhabert 2005,2005,9 genes,Guilhabert-2005-Identification of Xylella fast,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4889,PHI:3660,UniProt,Q87C95,GenBank,AAO29049,,,Temecula1,BfeA (PD_1198),,PD1198::EZ::TN<Kan-2>Tnp,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,"ferric enterobacyin receptor, BfeA",,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,16134898,PubMed,10.1094/MPMI-18-0856,Mol Plant Microbe Interact. 2005 Aug;18(8):856-68,bckirkpatrick@ucdavis.edu,,M R Guilhabert 2005,2005,9 genes,Guilhabert-2005-Identification of Xylella fast,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4890,PHI:3661,UniProt,Q87BB6,GenBank,PD_1542,,,Temecula1,Dmt (PD_1542),,PD1542::EZ::TN<Kan-2>Tnp,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,"mannosyltransferase (LPS biosynthesis), DMT",,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,16134898,PubMed,10.1094/MPMI-18-0856,Mol Plant Microbe Interact. 2005 Aug;18(8):856-68,bckirkpatrick@ucdavis.edu,,M R Guilhabert 2005,2005,9 genes,Guilhabert-2005-Identification of Xylella fast,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4891,PHI:3662,UniProt,Q87ET0,GenBank,AAO28109,,,Temecula1,PspB (PD_0218),,PD0218::EZ::TN<Kan-2>Tnp,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,"serine protease, PspB",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,16134898,PubMed,10.1094/MPMI-18-0856,Mol Plant Microbe Interact. 2005 Aug;18(8):856-68,bckirkpatrick@ucdavis.edu,,M R Guilhabert 2005,2005,9 genes,Guilhabert-2005-Identification of Xylella fast,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4892,PHI:3663,UniProt,Q87DK1,GenBank,AAO28552,,,Temecula1,gluP (PD_0681),,PD0681::EZ::TN<Kan-2>Tnp,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,"glucose kinase, Glk",,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,16134898,PubMed,10.1094/MPMI-18-0856,Mol Plant Microbe Interact. 2005 Aug;18(8):856-68,bckirkpatrick@ucdavis.edu,,M R Guilhabert 2005,2005,9 genes,Guilhabert-2005-Identification of Xylella fast,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4893,PHI:3664,UniProt,F7NA98,GenBank,PD_0875,,,EB92.1,PaaK (PD_0875),,PD0875::EZ::TN<Kan-2>Tnp,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,"coenzyme F390 synthetase, PaaK",,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,16134898,PubMed,10.1094/MPMI-18-0856,Mol Plant Microbe Interact. 2005 Aug;18(8):856-68,bckirkpatrick@ucdavis.edu,,M R Guilhabert 2005,2005,9 genes,Guilhabert-2005-Identification of Xylella fast,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4894,PHI:3665,UniProt,Q87C51,GenBank,PD_1244,,,Temecula1,PD_1244,,PD1244::EZ::TN<Kan-2>Tnp,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,16134898,PubMed,10.1094/MPMI-18-0856,Mol Plant Microbe Interact. 2005 Aug;18(8):856-68,bckirkpatrick@ucdavis.edu,,M R Guilhabert 2005,2005,9 genes,Guilhabert-2005-Identification of Xylella fast,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4895,PHI:3666,UniProt,Q87AN1,GenBank,PD_1792,,,Temecula1,HxfB (PD_1792) (pspA),,PD1792::Tn903 kan-2,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,"hemagglutinin adhesin, secreted protein",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,16134898,PubMed,10.1094/MPMI-18-0856,Mol Plant Microbe Interact. 2005 Aug;18(8):856-68,bckirkpatrick@ucdavis.edu,,M R Guilhabert 2005,2005,9 genes,Guilhabert-2005-Identification of Xylella fast,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4896,PHI:3667,,no data found,GenBank,PD_1246,,,,PD_1246,,PD1246::EZ::TN<Kan-2>Tnp,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,HL secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,16134898,PubMed,10.1094/MPMI-18-0856,Mol Plant Microbe Interact. 2005 Aug;18(8):856-68,bckirkpatrick@ucdavis.edu,Non functional gene,M R Guilhabert 2005,2005,9 genes,Guilhabert-2005-Identification of Xylella fast,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4897,PHI:4468,UniProt,A0A068BFA5,GenBank,AIC84211,,,Fl1,mkkA,,,,,,,35717,Epichloe festucae,877507,Fl1,,monocots,4522,Lolium perenne (related: perennial ryegrass),,,,leaf,cell-wall integrity MAPK,,,CWI MAPK pathway,increased virulence (hypervirulence),,,,,,increased,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25303335,PubMed,10.1094/MPMI-06-14-0183-R,Mol Plant Microbe Interact. 2015 Jan;28(1):69-85,d.b.scott@massey.ac.nz,,Y Becker 2015,2015,1 gene,Becker-2015-The Fungal Cell-Wall Integrity MAP,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4898,PHI:4469,UniProt,Q63R64,GenBank,CAH36819,,,K96243,wcb,,,,,,,28450,Burkholderia pseudomallei,,JW280,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,capsule formation,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25569630,PubMed,10.1371/journal.pntd.0003441,PLoS Negl Trop Dis. 2015 Jan 8;9(1):e3441,jonathan.warawa@louisville.edu,"The capsule mutant was attenuated 6.8 fold, while the T3SS3 mutant was attenuated 290 fold, demonstrating that T3SS3 is critical to respiratory melioidosis.",M G Gutierrez 2015,2015,2 genes,Gutierrez-2015-Type 3 secretion system cluster,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4899,PHI:4470,UniProt,Q3JLG7,GenBank,ABA52956,,,1710b,sctU,chromosome II,,,,,,28450,Burkholderia pseudomallei,,JW280,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,type 3 secretion system cluster 3,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25569630,PubMed,10.1371/journal.pntd.0003441,PLoS Negl Trop Dis. 2015 Jan 8;9(1):e3441,jonathan.warawa@louisville.edu,"The capsule mutant was attenuated 6.8 fold, while the T3SS3 mutant was attenuated 290 fold, demonstrating that T3SS3 is critical to respiratory melioidosis.",M G Gutierrez 2015,2015,2 genes,Gutierrez-2015-Type 3 secretion system cluster,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4900,PHI:4471,UniProt,Q4WTH5,GenBank,EAL90257,,,Af293,PtcB,chromosome 1,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,phosphatase,,,HOG (high osmolarity glycerol response) pathway,loss of pathogenicity,,,,,,aberrant,,aberrant,,no,caspofungin; anidulafungin; voriconazole; itraconazole,caspofungin: CHEBI:474180; anidulafungin: CHEBI:55346; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076,,,,,gene deletion: full; gene complementation,,,RP,25597841,PubMed,10.1111/mmi.12919,Mol Microbiol. 2015 Jan 19,ggoldman@usp.br,"No differences susceptibility to caspofungin or Anidulafungin were observed. However, the ptcB mutant was more sensitive to voriconazole and itraconazole.",L K Winkelströter 2015,2015,1 gene,Winkelstroter-2015-High Osmolarity Glycerol re,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4901,PHI:4472,UniProt,P9WPB5,GenBank,AAC43488,,,H37Ra,cmaA2,,,,,,,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,cyclopropane-mycolic acid synthase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,16741578,PubMed,10.1172/JCI27335,J Clin Invest. 2006 Jun;116(6):1660-7,glickmam@mskcc.org,,V Rao 2006,2006,1 gene,Rao-2006-Trans-cyclopropanation of mycolic aci,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4902,PHI:4473,UniProt,D2TJQ0,GenBank,CBG89691,,,ICC168,croI,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,,quorum sensing,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,17557113,PubMed,10.1038/sj.embor.7400984,EMBO Rep. 2007 Jul;8(7):698-703. Epub 2007 Jun 8,gpcs@mole.bio.cam.ac.uk,,S J Coulthurst 2007,2007,2 genes,Coulthurst-2007-Quorum sensing has an unexpect,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4903,PHI:4475,UniProt,G4MUR7,GenBank,EHA54040,,,70-15,MoTup1,chromosome 2,pCX62-MoTUP1-U-D,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,general transcriptional repressor,,,,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced; aberrant,,no,SDS; sorbitol,D-sorbitol: CHEBI:17924; SDS: CHEBI:8984,,,,,gene disruption; gene complementation,,,RP,25583028,PubMed,10.1111/mpp.12235,Mol Plant Pathol. 2015 Jan 13,zhgzhang@njau.edu.cn,,Y Chen 2015,2015,1 gene,"Chen-2015-MoTup1 Is Required for Growth, Conid",Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4904,PHI:4475,UniProt,G4MUR7,GenBank,EHA54040,,,70-15,MoTup1,chromosome 2,pCX62-MoTUP1-U-D,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,general transcriptional repressor,,,,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced; aberrant,,no,SDS; sorbitol,D-sorbitol: CHEBI:17924; SDS: CHEBI:8984,,,,,gene disruption; gene complementation,,,RP,25583028,PubMed,10.1111/mpp.12235,Mol Plant Pathol. 2015 Jan 13,zhgzhang@njau.edu.cn,,Y Chen 2015,2015,1 gene,"Chen-2015-MoTup1 Is Required for Growth, Conid",Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4905,PHI:4476,,no data found,GenBank,XP_001546353,,,B05.10,BcMctA,,pCAMBIABar-deltamctA,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,putative monocarboxylate transporter,,,,reduced virulence,,,,,,increased,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25634672,PubMed,10.1007/s00294-015-0474-1,Curr Genet. 2015 Jan 30,thzhu@zjut.edu.cn,"Disruption of the gene decreased the growth rate on the medium with monocarboxylate (acetate or pyruvate) as the sole carbon sources, but not affected on lactate.",Z Cui 2015,2015,1 gene,"Cui-2015-BcMctA, a putative monocarboxylate tr",Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4906,PHI:4477,UniProt,H2FL17,GenBank,AEX88335,,,EB 92-3,RpfF,,pFXFkan rpfC-Kanr-rpfF*(E141A E161A),,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,stem,regulator of pathogenicity factors,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24056101,PubMed,10.1128/JB.00713-13,J Bacteriol. 2013 Dec;195(23):5273-84,icelab@berkeley.edu,,M Ionescu 2013,2013,1 gene,Ionescu-2013-Diffusible signal factor (DSF) sy,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4907,PHI:4479,UniProt,P96320,GenBank,CAA70978,,,Ea1/79,rcsB,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,amylovoran production and pathogenticity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25577258,PubMed,10.1007/s00438-015-0988-8,Mol Genet Genomics. 2015 Jan 11,zhao888@illinois.edu,,V Ancona 2015,2015,4 genes,Ancona-2015-Conserved aspartate and lysine res,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4908,PHI:4480,UniProt,A0A034UYN5,GenBank,GAJ89527,,,NBRC 12687,rcsC,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,amylovoran production and pathogenticity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25577258,PubMed,10.1007/s00438-015-0988-8,Mol Genet Genomics. 2015 Jan 11,zhao888@illinois.edu,,V Ancona 2015,2015,4 genes,Ancona-2015-Conserved aspartate and lysine res,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4909,PHI:4479,UniProt,P96320,GenBank,CAA70978,,,Ea1/79,rcsB,,,,,,PHI:4480,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,amylovoran production and pathogenticity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25577258,PubMed,10.1007/s00438-015-0988-8,Mol Genet Genomics. 2015 Jan 11,zhao888@illinois.edu,,V Ancona 2015,2015,4 genes,Ancona-2015-Conserved aspartate and lysine res,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4910,PHI:4478,UniProt,P20098,GenBank,AAA24864,,,T,rcsA,,,,,,PHI:4479,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,amylovoran production and pathogenticity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25577258,PubMed,10.1007/s00438-015-0988-8,Mol Genet Genomics. 2015 Jan 11,zhao888@illinois.edu,,V Ancona 2015,2015,4 genes,Ancona-2015-Conserved aspartate and lysine res,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4911,PHI:4479,UniProt,P96320,GenBank,CAA70978,,,Ea1/79,rcsB,,,,,,PHI:4478,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,amylovoran production and pathogenticity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25577258,PubMed,10.1007/s00438-015-0988-8,Mol Genet Genomics. 2015 Jan 11,zhao888@illinois.edu,,V Ancona 2015,2015,4 genes,Ancona-2015-Conserved aspartate and lysine res,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4912,PHI:4478,UniProt,P20098,GenBank,AAA24864,,,T,rcsA,,,,,,PHI:4479; PHI:4480; PHI:4481,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,amylovoran production and pathogenticity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25577258,PubMed,10.1007/s00438-015-0988-8,Mol Genet Genomics. 2015 Jan 11,zhao888@illinois.edu,,V Ancona 2015,2015,4 genes,Ancona-2015-Conserved aspartate and lysine res,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4913,PHI:4479,UniProt,P96320,GenBank,CAA70978,,,Ea1/79,rcsB,,,,,,PHI:4478; PHI:4480; PHI:4481,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,amylovoran production and pathogenticity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25577258,PubMed,10.1007/s00438-015-0988-8,Mol Genet Genomics. 2015 Jan 11,zhao888@illinois.edu,,V Ancona 2015,2015,4 genes,Ancona-2015-Conserved aspartate and lysine res,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4914,PHI:4480,UniProt,A0A034UYN5,GenBank,GAJ89527,,,NBRC 12687,rcsC,,,,,,PHI:4478; PHI:4479; PHI:4481,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,amylovoran production and pathogenticity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25577258,PubMed,10.1007/s00438-015-0988-8,Mol Genet Genomics. 2015 Jan 11,zhao888@illinois.edu,,V Ancona 2015,2015,4 genes,Ancona-2015-Conserved aspartate and lysine res,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4915,PHI:4481,UniProt,A0A034UTT8,GenBank,GAJ89525,,,NBRC 12687,rcsD,,,,,,PHI:4478; PHI:4479; PHI:4480,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,23211,Pyrus communis (related: pear),,,,fruit,amylovoran production and pathogenticity,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25577258,PubMed,10.1007/s00438-015-0988-8,Mol Genet Genomics. 2015 Jan 11,zhao888@illinois.edu,,V Ancona 2015,2015,4 genes,Ancona-2015-Conserved aspartate and lysine res,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4916,PHI:4481,UniProt,F8ILW3,GenBank,AEJ24716,,,ATCC 35246,sagD,,pSET4S:sagD,,,,,1336,Streptococcus equi,1051072,subsp. zooepidemicus strain C74-63,septicemia; meningitis; mastitis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,streptolysin S biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25595678,PubMed,10.1016/j.micpath.2015.01.004,Microb Pathog. 2015 Feb;79:31-40,fhj@njau.edu.cn,,Z Ma 2015,2015,1 gene,Ma-2015-Identification of novel genes expresse,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4917,PHI:4482,UniProt,A7F952,GenBank,EDO00263,,,1980 UF-70,SSITL,,,,,,,5180,Sclerotinia sclerotiorum,,Ep-1PNA367,white mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,secretory protein that represses host resistance,,,,reduced virulence,,,,,,,,reduced; aberrant,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23342034,PubMed,10.1371/journal.pone.0053901,PLoS One. 2013;8(1):e53901,daohongjiang@mail.hzau.edu.cn,,W Zhu 2013,2013,1 gene,Zhu-2013-A secretory protein of necrotrophic f,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4918,PHI:4482,UniProt,A7F952,GenBank,EDO00263,,,1980 UF-70,SSITL,,,,,,,5180,Sclerotinia sclerotiorum,,Ep-1PNA367,white mold,eudicots,3708,Brassica napus (related: rape),,,,leaf,secretory protein that represses host resistance,,,,reduced virulence,,,,,,,,reduced; aberrant,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23342034,PubMed,10.1371/journal.pone.0053901,PLoS One. 2013;8(1):e53901,daohongjiang@mail.hzau.edu.cn,,W Zhu 2013,2013,1 gene,Zhu-2013-A secretory protein of necrotrophic f,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4919,PHI:4483,UniProt,Q63K45,GenBank,CAH38994,,,K96243,BprD,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,Burkholderia secretion apparatus (Bsa) type 3 secretion system (T3SS),,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25635268,PubMed,10.1074/mcp.M114.044875,Mol Cell Proteomics. 2015 Jan 29. pii: mcp.M114.044875,jo.stevens@roslin.ed.ac.uk,,C W Vander Broek 2015,2015,2 genes,Vander Broek-2015-Quantitative proteomic analy,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4920,PHI:4484,UniProt,Q63K38,GenBank,CAH39001,,,K96243,BapA,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,Burkholderia secretion apparatus (Bsa) type 3 secretion system (T3SS),,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25635268,PubMed,10.1074/mcp.M114.044875,Mol Cell Proteomics. 2015 Jan 29. pii: mcp.M114.044875,jo.stevens@roslin.ed.ac.uk,,C W Vander Broek 2015,2015,2 genes,Vander Broek-2015-Quantitative proteomic analy,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4921,PHI:4485,UniProt,Q5APU3,GenBank,EAL04853,,,SC5314,Sac1,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,phospholipase,,,,reduced virulence,,,,,,,,reduced; aberrant,reduced,no,calcofluor white (CFW); Congo red; hygromycin B: CHEBI:16976,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,25575432,PubMed,10.1016/j.fgb.2014.12.007,Fungal Genet Biol. 2015 Jan 6. pii: S1087-1845(14)00223-0,nklimingchun@163.com,"Sac1 is essential for actin organization, hyphal development, cell wall integrity and pathogenicity in C. albicans.",B Zhang 2015,2015,1 gene,Zhang-2015-The actin-related protein Sac1 is r,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4922,PHI:4486,UniProt,Q79G00,GenBank,AFN48014,,,H37Rv,mce1R,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,negative transcriptional regulator,,,,increased virulence (hypervirulence),,,,,larger granulomatous lesions,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,17223927,PubMed,10.1111/j.1462-5822.2006.00870.x,Cell Microbiol. 2007 May;9(5):1275-83. Epub 2007 Jan 11,lwriley@berkeley.edu,,Y Uchida 2007,2007,1 gene,Uchida-2007-Accelerated immunopathological res,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4923,PHI:4487,UniProt,G2L851,GenBank,AEO75627,,,M18,QscR,,pKL13 with 1.6 kb aacC1 interrupting qscR ApR GmR,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,modulator of quorum-sensing signal synthesis,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,11226312,PubMed,10.1073/pnas.051624298,Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2752-7,everett-greenberg@uiowa.edu,,S A Chugani 2001,2001,1 gene,"Chugani-2001-QscR, a modulator of quorum-sensi",Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4924,PHI:4488,UniProt,Q9X7H4,GenBank,AAD22496,,,PAO1,RsaL,,rsaL::ISlacZ/hah,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,,global regulator,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,trimethoprim; cloramphenicol; norfloxacin; nalidixic acid,trimethoprim: CHEBI:45924; cloramphenicol: CHEBI:17698; norfloxacin: CHEBI:100246; nalidixic acid: CHEBI:100147,,,,,gene mutation; gene complementation,,,RP,19878323,PubMed,10.1111/j.1574-6968.2009.01817.x,FEMS Microbiol Lett. 2009 Dec;301(2):210-7,leoni@bio.uniroma3.it,"The rsaLmutant showed enhanced antibiotic susceptibility to trimethoprim, cloramphenicol, norfloxacin and nalidixic acid, with respect to the wild type.",G Rampioni 2009,2009,1 gene,Rampioni-2009-Contribution of the RsaL global,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4925,PHI:4489,UniProt,G4NGH0,GenBank,EHA47127,,,70-15,C3HC,,,,MAP1,GenBank: EHA54985; UniProt: G4MVR9,,318829,Magnaporthe oryzae,,JL0910,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Jijing 88,,,leaf,C3HC-zinc finger domain-containing protein,,,,reduced virulence,,no,,,,reduced,,wild type; aberrant,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,25605006,PubMed,10.1111/mpp.1224,Mol Plant Pathol. 2015 Jan 20,zhang_sh@jlu.edu.cn,All mutants showed reduced conidiation and sensitivity to hydrogen peroxide.,X CUI 2015,2015,7 genes,Cui-2015-Proteins interacting with mitochondri,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4926,PHI:4490,UniProt,G5EGV6,GenBank,EAQ70601,,,70-15,C2H2,,,,MAP1,GenBank: EHA54985; UniProt: G4MVR9,,318829,Magnaporthe oryzae,,JL0910,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Jijing 88,,,leaf,C2H2-zinc finger domain-containing protein,,,,increased virulence (hypervirulence),,no,,,,reduced,,wild type,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,25605006,PubMed,10.1111/mpp.1224,Mol Plant Pathol. 2015 Jan 20,zhang_sh@jlu.edu.cn,All mutants showed reduced conidiation and sensitivity to hydrogen peroxide.,X CUI 2015,2015,7 genes,Cui-2015-Proteins interacting with mitochondri,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4927,PHI:4491,UniProt,G4MRB4,GenBank,EHA58239,,,70-15,SHM,,,,MAP1,GenBank: EHA54985; UniProt: G4MVR9,,318829,Magnaporthe oryzae,,JL0910,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Jijing 88,,,leaf,serine hydroxymethyltransferase,,,,reduced virulence,,no,,,,reduced,,wild type,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,25605006,PubMed,10.1111/mpp.1224,Mol Plant Pathol. 2015 Jan 20,zhang_sh@jlu.edu.cn,All mutants showed reduced conidiation and sensitivity to hydrogen peroxide.,X CUI 2015,2015,7 genes,Cui-2015-Proteins interacting with mitochondri,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4928,PHI:4492,UniProt,G4NC32,GenBank,EHA49035,,,70-15,RanBP,,,,MAP1,GenBank: EHA54985; UniProt: G4MVR9,,318829,Magnaporthe oryzae,,JL0910,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Jijing 88,,,leaf,RanGTP-binding protein,,,,loss of pathogenicity,,no,,,,reduced,,reduced,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,25605006,PubMed,10.1111/mpp.1224,Mol Plant Pathol. 2015 Jan 20,zhang_sh@jlu.edu.cn,All mutants showed reduced conidiation and sensitivity to hydrogen peroxide.,X CUI 2015,2015,7 genes,Cui-2015-Proteins interacting with mitochondri,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4929,PHI:4493,UniProt,G4MS28,GenBank,EHA57494,,,70-15,CGT,,,,MAP1,GenBank: EHA54985; UniProt: G4MVR9,,318829,Magnaporthe oryzae,,JL0910,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Jijing 88,,,leaf,ceramide glucosyltransferase,,,,increased virulence (hypervirulence),,no,,,,reduced,,wild type,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,25605006,PubMed,10.1111/mpp.1224,Mol Plant Pathol. 2015 Jan 20,zhang_sh@jlu.edu.cn,All mutants showed reduced conidiation and sensitivity to hydrogen peroxide.,X CUI 2015,2015,7 genes,Cui-2015-Proteins interacting with mitochondri,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4930,PHI:4494,UniProt,G4MMH7,GenBank,EHA56955,,,70-15,AnnA7,,,,MAP1,GenBank: EHA54985; UniProt: G4MVR9,,318829,Magnaporthe oryzae,,JL0910,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Jijing 88,,,leaf,annexin A7,,,,reduced virulence,,no,,,,reduced; aberrant,,wild type; aberrant,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,25605006,PubMed,10.1111/mpp.1224,Mol Plant Pathol. 2015 Jan 20,zhang_sh@jlu.edu.cn,All mutants showed reduced conidiation and sensitivity to hydrogen peroxide.,X CUI 2015,2015,7 genes,Cui-2015-Proteins interacting with mitochondri,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4931,PHI:4495,UniProt,G4MPB7,GenBank,EHA57170,,,70-15,Bud6p,,,,MAP1,GenBank: EHA54985; UniProt: G4MVR9,,318829,Magnaporthe oryzae,,JL0910,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Jijing 88,,,leaf,bud site selection or actin interacting protein,,,,unaffected pathogenicity,,no,,,,reduced; aberrant,,reduced,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,25605006,PubMed,10.1111/mpp.1224,Mol Plant Pathol. 2015 Jan 20,zhang_sh@jlu.edu.cn,All mutants showed reduced conidiation and sensitivity to hydrogen peroxide.,X CUI 2015,2015,7 genes,Cui-2015-Proteins interacting with mitochondri,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4932,PHI:4496,UniProt,P9WMK1,GenBank,AAB21317,,,,hspX,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,encodes a 16-kDa-crystallin-like protein that is a major antigen,,,,increased virulence (hypervirulence),,no,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,16428728,PubMed,10.1128/IAI.74.2.861-868.2006,Infect Immun. 2006 Feb;74(2):861-8,acoates@sghms.ac.uk,,Y Hu 2015,2006,1 gene,Hu-2006-Deletion of the Mycobacterium tubercul,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4933,PHI:4497,UniProt,P36556,GenBank,AAA72365,,,LT2,PmrA,,,,ssrB,GenBank: CBW17421; UniProt: A0A0H3NKV1,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,liver; spleen,lipopolysaccharide modification regulator,,,,increased virulence (hypervirulence),,no,,,,,,,,no,,,,,,,gene mutation,,,RP,23690578,PubMed,10.1073/pnas.1303420110,Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9499-504,eduardo.groisman@yale.edu,,J Choi 2013,2013,2 genes,Choi-2013-The lipopolysaccharide modification,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4934,PHI:4498,UniProt,E1WFQ7,GenBank,CBW17421,,,SL1344,ssrB,,,,PmrA,GenBank: AAA72365; UniProt: P36556,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,liver; spleen,two-component response regulator,,,,increased virulence (hypervirulence),,no,,,,,,,,no,,,,,,,gene mutation,,,RP,23690578,PubMed,10.1073/pnas.1303420110,Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9499-504,eduardo.groisman@yale.edu,,J Choi 2013,2013,2 genes,Choi-2013-The lipopolysaccharide modification,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4935,PHI:4499,UniProt,R4Z9S0,GenBank,CCO74924,,,2-22,rovS,,,,,,,1311,Streptococcus agalactiae,211110,NEM316,group B streptococcal infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver; brain,transcriptional regulator,,,,reduced virulence,,no,,,,,,,,no,,,,,,,gene mutation,,,RP,25604789,PubMed,10.1128/mBio.02306-14,MBio. 2015 Jan 20;6(1). pii: e02306-14,david.perez@jouy.inra.fr,"No differences were observed in the amounts of bacteria present in the lungs and brain. However, bacterial counts were significantly lower in the spleens and livers of mice infected with the rovS mutant and the shp mutant.",D Pérez-Pascual 2015,2015,2 genes,Perez-Pascual-2015-RovS and Its Associated Sig,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4936,PHI:4500,,no data found,,,,,,shp,,,,,,,1311,Streptococcus agalactiae,211110,NEM316,group B streptococcal infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver; brain,signaling molecules,,,,reduced virulence,,no,,,,,,,,no,,,,,,,gene mutation,,,RP,25604789,PubMed,10.1128/mBio.02306-14,MBio. 2015 Jan 20;6(1). pii: e02306-14,david.perez@jouy.inra.fr,"No differences were observed in the amounts of bacteria present in the lungs and brain. However, bacterial counts were significantly lower in the spleens and livers of mice infected with the rovS mutant and the shp mutant.",D Pérez-Pascual 2015,2015,2 genes,Perez-Pascual-2015-RovS and Its Associated Sig,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4937,PHI:4501,,no data found,GenBank,KP099423,,,B0510,bclae1,,,,BcVEL1,GenBank: CCK35905; UniProt: L0PQB7,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,"A member of the VELVET complex, shown to affect light-dependent differentiation, the formation of oxalic acid (OA) and virulence.",,,,reduced virulence,,yes,,,,,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,altered gene expression / gene regulation: overexpression,,,RP,25625818,PubMed,10.1094/MPMI-12-14-0411-R,Mol Plant Microbe Interact. 2015 Jan 27,julia.schumacher@wwu.de,"Both mutants lost the ability to produce OA, to colonize the host tissue and to form sclerotia.",J Schumacher 2015,2015,2 genes,Schumacher-2015-The VELVET complex in the gray,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4938,PHI:4502,UniProt,L0PQB7,GenBank,CCK35905,,,T4,BcVEL1,,,,bclae1,EMBL: KP099423; UniProt: A0A0B5L7R4,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,"A member of the VELVET complex, shown to affect light-dependent differentiation, the formation of oxalic acid (OA) and virulence.",,,,reduced virulence,,yes,,,,,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,altered gene expression / gene regulation: overexpression,,,RP,25625818,PubMed,10.1094/MPMI-12-14-0411-R,Mol Plant Microbe Interact. 2015 Jan 27,julia.schumacher@wwu.de,"Both mutants lost the ability to produce OA, to colonize the host tissue and to form sclerotia.",J Schumacher 2015,2015,2 genes,Schumacher-2015-The VELVET complex in the gray,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4939,PHI:4501,,no data found,GenBank,KP099423,,,B0510,bclae1,,,,BcVEL1,GenBank: CCK35905; UniProt: L0PQB7,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,"A member of the VELVET complex, shown to affect light-dependent differentiation, the formation of oxalic acid (OA) and virulence.",,,,reduced virulence,,no,,yes,,reduced,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full,,,RP,25625818,PubMed,10.1094/MPMI-12-14-0411-R,Mol Plant Microbe Interact. 2015 Jan 27,julia.schumacher@wwu.de,"Both mutants lost the ability to produce OA, to colonize the host tissue and to form sclerotia.",J Schumacher 2015,2015,2 genes,Schumacher-2015-The VELVET complex in the gray,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4940,PHI:4502,UniProt,L0PQB7,GenBank,CCK35905,,,T4,BcVEL1,,,,bclae1,EMBL: KP099423; UniProt: A0A0B5L7R4,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,"A member of the VELVET complex, shown to affect light-dependent differentiation, the formation of oxalic acid (OA) and virulence.",,,,reduced virulence,,no,,yes,,reduced,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full,,,RP,25625818,PubMed,10.1094/MPMI-12-14-0411-R,Mol Plant Microbe Interact. 2015 Jan 27,julia.schumacher@wwu.de,"Both mutants lost the ability to produce OA, to colonize the host tissue and to form sclerotia.",J Schumacher 2015,2015,2 genes,Schumacher-2015-The VELVET complex in the gray,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4941,PHI:4503,UniProt,Q9A1J4,GenBank,RNPA_STRP1,,,M1,FasX,,,,M2.113; M6.tee6; M28.fctA,,,1314,Streptococcus pyogenes,301447,serotype M1,toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),B6.Cg-Tg(Alb-PLG)1Dgi/J,,,,regulates the expression of pili and the thrombolytic agent streptokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25586884,PubMed,10.1111/mmi.12935,Mol Microbiol. 2015 Jan 14,psumby@medicine.nevada.edu,This is a small regulatory RNA that bind to other mRNAs,J L Danger 2015,2015,1 gene,Danger-2015-The small regulatory RNA FasX enha,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4942,PHI:4504,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,transcription factor; involved in patulin production,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,RP,25625822,PubMed,10.1094/MPMI-12-14-0398-FI,Mol Plant Microbe Interact. 2015 Jan 27,tsp@ibcas.ac.cn,,B Li 2015,2015,2 genes,Li-2015-Genomic characterization reveals insig,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4943,PHI:4505,UniProt,A0A075TRC0,GenBank,AIG62146,,,NRRL 35695,PePatK,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,encodes a 6-methylsalicylic acid synthase; patulin production,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,RP,25625822,PubMed,10.1094/MPMI-12-14-0398-FI,Mol Plant Microbe Interact. 2015 Jan 27,tsp@ibcas.ac.cn,,B Li 2015,2015,2 genes,Li-2015-Genomic characterization reveals insig,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4944,PHI:4504,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: pear),cv. Huangguan,,,fruit,transcription factor; involved in patulin production,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,RP,25625822,PubMed,10.1094/MPMI-12-14-0398-FI,Mol Plant Microbe Interact. 2015 Jan 27,tsp@ibcas.ac.cn,,B Li 2015,2015,2 genes,Li-2015-Genomic characterization reveals insig,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4945,PHI:4505,UniProt,A0A075TRC0,GenBank,AIG62146,,,NRRL 35695,PePatK,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: pear),cv. Huangguan,,,fruit,encodes a 6-methylsalicylic acid synthase; patulin production,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,RP,25625822,PubMed,10.1094/MPMI-12-14-0398-FI,Mol Plant Microbe Interact. 2015 Jan 27,tsp@ibcas.ac.cn,,B Li 2015,2015,2 genes,Li-2015-Genomic characterization reveals insig,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4946,PHI:4504,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,122118,Prunus americana (related: goose plum),,,,fruit,transcription factor; involved in patulin production,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,RP,25625822,PubMed,10.1094/MPMI-12-14-0398-FI,Mol Plant Microbe Interact. 2015 Jan 27,tsp@ibcas.ac.cn,,B Li 2015,2015,2 genes,Li-2015-Genomic characterization reveals insig,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4947,PHI:4505,UniProt,A0A075TRC0,GenBank,AIG62146,,,NRRL 35695,PePatK,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,122118,Prunus americana (related: goose plum),,,,fruit,encodes a 6-methylsalicylic acid synthase; patulin production,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,RP,25625822,PubMed,10.1094/MPMI-12-14-0398-FI,Mol Plant Microbe Interact. 2015 Jan 27,tsp@ibcas.ac.cn,,B Li 2015,2015,2 genes,Li-2015-Genomic characterization reveals insig,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4948,PHI:4506,UniProt,K9Y567,GenBank,AFZ39117,,,E2368,So (soft),,,,,,,35717,Epichloe festucae,696363,E2368,,monocots,4606,Lolium arundinaceum (related: tall fescue),,,,leaf,symbiotic,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,23042130,PubMed,10.1128/EC.00191-12,Eukaryot Cell. 2012 Dec;11(12):1463-71,kdcraven@noble.org,The disruption of the genes leads to a disruption of the symbiotic relationship and leads to plant death,N D Charlton 2012,2012,1 gene,Charlton-2012-Deletion of the fungal gene soft,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4949,PHI:4507,UniProt,G9J651,GenBank,AEU17941,,,ATCC 8199,WtsE,,,,,,,66269,Pantoea stewartii,660596,subsp. stewartii strain DC283,Stewart's wilt; leaf blight,monocots,4577,Zea mays (related: maize),cv. Seneca Horizon,,,leaf,AvrE-family type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,glyphosate,glyphosate: CHEBI:27744,,,,,gene mutation; gene complementation,,,RP,25635112,PubMed,10.1104/pp.114.253120,Plant Physiol. 2015 Mar;167(3):1117-35,mackey.86@osu.edu,,J A Asselin 2015,2015,1 gene,Asselin-2015-Perturbation of Maize Phenylpropa,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4950,PHI:4508,UniProt,A7EU07,GenBank,EDN92949,,,1980 UF-70,Ss-odc1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf,oxalate decarboxylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25597873,PubMed,10.1111/mpp.12239.,Mol Plant Pathol. 2015 Jan 18,rollinsj@ufl.edu,,X Liang 2015,2015,2 genes,Liang-2015-Fungal oxalate decarboxylase activi,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4951,PHI:4509,UniProt,A7EZM9,GenBank,EDN94921,,,1980 UF-70,Ss-odc2,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf,oxalate decarboxylase,,,,reduced virulence,,yes,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25597873,PubMed,10.1111/mpp.12239.,Mol Plant Pathol. 2015 Jan 18,rollinsj@ufl.edu,,X Liang 2015,2015,2 genes,Liang-2015-Fungal oxalate decarboxylase activi,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4952,PHI:4508,UniProt,A7EU07,GenBank,EDN92949,,,1980 UF-70,Ss-odc1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Bush Blue Lake 47,,,leaf,oxalate decarboxylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25597873,PubMed,10.1111/mpp.12239.,Mol Plant Pathol. 2015 Jan 18,rollinsj@ufl.edu,,X Liang 2015,2015,2 genes,Liang-2015-Fungal oxalate decarboxylase activi,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4953,PHI:4509,UniProt,A7EZM9,GenBank,EDN94921,,,1980 UF-70,Ss-odc2,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Bush Blue Lake 47,,,leaf,oxalate decarboxylase,,,,reduced virulence,,yes,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25597873,PubMed,10.1111/mpp.12239.,Mol Plant Pathol. 2015 Jan 18,rollinsj@ufl.edu,,X Liang 2015,2015,2 genes,Liang-2015-Fungal oxalate decarboxylase activi,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4954,PHI:4508,UniProt,A7EU07,GenBank,EDN92949,,,1980 UF-70,Ss-odc1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf; petiole,oxalate decarboxylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25597873,PubMed,10.1111/mpp.12239.,Mol Plant Pathol. 2015 Jan 18,rollinsj@ufl.edu,,X Liang 2015,2015,2 genes,Liang-2015-Fungal oxalate decarboxylase activi,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4955,PHI:4509,UniProt,A7EZM9,GenBank,EDN94921,,,1980 UF-70,Ss-odc2,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf; petiole,oxalate decarboxylase,,,,reduced virulence,,yes,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25597873,PubMed,10.1111/mpp.12239.,Mol Plant Pathol. 2015 Jan 18,rollinsj@ufl.edu,,X Liang 2015,2015,2 genes,Liang-2015-Fungal oxalate decarboxylase activi,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4956,PHI:4508,UniProt,A7EU07,GenBank,EDN92949,,,1980 UF-70,Ss-odc1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4045,Apium graveolens (no common name found),dulce group,,,stem,oxalate decarboxylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25597873,PubMed,10.1111/mpp.12239.,Mol Plant Pathol. 2015 Jan 18,rollinsj@ufl.edu,,X Liang 2015,2015,2 genes,Liang-2015-Fungal oxalate decarboxylase activi,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4957,PHI:4509,UniProt,A7EZM9,GenBank,EDN94921,,,1980 UF-70,Ss-odc2,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4045,Apium graveolens (no common name found),dulce group,,,stem,oxalate decarboxylase,,,,reduced virulence,,yes,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25597873,PubMed,10.1111/mpp.12239.,Mol Plant Pathol. 2015 Jan 18,rollinsj@ufl.edu,,X Liang 2015,2015,2 genes,Liang-2015-Fungal oxalate decarboxylase activi,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4958,PHI:4510,UniProt,Q4P4N7,GenBank,EAK85870,,,521,pep4,,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut,monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,leaf,encoding the vacuolar acid proteinase,,,,reduced virulence,no,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25597948,PubMed,10.1111/mpp.12240,Mol Plant Pathol. 2015 Jan 18,lourdesvilla@hotmail.com,,C. V. SOBERANES-GUTIÉRREZ 2015,2015,1 gene,Soberanes-Gutie-2015-The pep4 gene encoding pr,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4959,PHI:4511,UniProt,Q6XVY7,GenBank,YP_009078285,,,,ipgB1,,ipgB1::aphA-3,,,,,623,Shigella flexneri,1086030,M90T-Sm,shigellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial,,,RP,18316224,PubMed,10.1016/j.micinf.2007.11.011,Microbes Infect. 2008 Mar;10(3):260-8,aallaoui@ulb.ac.be,"Upon infection of the cornea in Guinea pigs, theipgB2mutant exhibiteda wild-type phenotype, theipgB1 mutant was hypervirulent and elicited a more pronounced proinflammatory response, while theipgB1 ipgB2mutant was highly attenuated. The attenuated phenotype of theipgB1 ipgB2mutant was confirmed using a murine pulmonary model of infectionand histopathology and immunochemistry studies.",A Hachani 2008,2008,2 genes,"Hachani-2008-IpgB1 and IpgB2, two homologous e.pdf",Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4960,PHI:4512,UniProt,Q9AJW7,GenBank,YP_006960253,,,5,ipgB2,,ipgB1::aphA-3,,,,,623,Shigella flexneri,1086030,M90T-Sm,shigellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial,,,RP,18316224,PubMed,10.1016/j.micinf.2007.11.011,Microbes Infect. 2008 Mar;10(3):260-8,aallaoui@ulb.ac.be,"Upon infection of the cornea in Guinea pigs, theipgB2mutant exhibiteda wild-type phenotype, theipgB1 mutant was hypervirulent and elicited a more pronounced proinflammatory response, while theipgB1 ipgB2mutant was highly attenuated. The attenuated phenotype of theipgB1 ipgB2mutant was confirmed using a murine pulmonary model of infectionand histopathology and immunochemistry studies.",A Hachani 2008,2008,2 genes,"Hachani-2008-IpgB1 and IpgB2, two homologous e.pdf",Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4961,PHI:4511,UniProt,Q6XVY7,GenBank,YP_009078285,,,,ipgB1,,ipgB1::aphA-3,,,,,623,Shigella flexneri,1086030,M90T-Sm,keratoconjunctivitis,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,cornea,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial,,,RP,18316224,PubMed,10.1016/j.micinf.2007.11.011,Microbes Infect. 2008 Mar;10(3):260-8,aallaoui@ulb.ac.be,"Upon infection of the cornea in Guinea pigs, theipgB2mutant exhibiteda wild-type phenotype, theipgB1 mutant was hypervirulent and elicited a more pronounced proinflammatory response, while theipgB1 ipgB2mutant was highly attenuated. The attenuated phenotype of theipgB1 ipgB2mutant was confirmed using a murine pulmonary model of infectionand histopathology and immunochemistry studies.",A Hachani 2008,2008,2 genes,"Hachani-2008-IpgB1 and IpgB2, two homologous e.pdf",Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4962,PHI:4512,UniProt,Q9AJW7,GenBank,YP_006960253,,,5,ipgB2,,ipgB1::aphA-3,,,,,623,Shigella flexneri,1086030,M90T-Sm,keratoconjunctivitis,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,cornea,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial,,,RP,18316224,PubMed,10.1016/j.micinf.2007.11.011,Microbes Infect. 2008 Mar;10(3):260-8,aallaoui@ulb.ac.be,"Upon infection of the cornea in Guinea pigs, theipgB2mutant exhibiteda wild-type phenotype, theipgB1 mutant was hypervirulent and elicited a more pronounced proinflammatory response, while theipgB1 ipgB2mutant was highly attenuated. The attenuated phenotype of theipgB1 ipgB2mutant was confirmed using a murine pulmonary model of infectionand histopathology and immunochemistry studies.",A Hachani 2008,2008,2 genes,"Hachani-2008-IpgB1 and IpgB2, two homologous e.pdf",Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4963,PHI:4513,UniProt,I1RWM0,GenBank,ESU14615,,,PH-1,FgMcm1,,,,Mat1-1-1; Fst12,"Mat1-1-1, UniProt: A9CCR5; Fst12, UniProt: Q8NKD8",,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,MADS-box transcription factor,,,,reduced virulence,yes,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25627073,PubMed,10.1111/1462-2920.12747,Environ Microbiol. 2015 Jan 28,liuhuiquan@nwsuaf.edu.cn,"FgMcm1 plays a critical role in the regulation of cell identity, sexual and asexual reproduction, secondary metabolism, and pathogenesis in F. graminearum",C Yang 2015,2015,2 genes,Yang-2015-The MADS-box transcription factor Fg,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4964,PHI:4514,UniProt,W7LTW0,GenBank,EWG38880,,,7600,Fvmcm1,,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Pioneer 2375,,,corn ear,MADS-box transcription factor,,,,reduced virulence,yes,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25627073,PubMed,10.1111/1462-2920.12747,Environ Microbiol. 2015 Jan 28,liuhuiquan@nwsuaf.edu.cn,"FgMcm1 plays a critical role in the regulation of cell identity, sexual and asexual reproduction, secondary metabolism, and pathogenesis in F. graminearum",C Yang 2015,2015,2 genes,Yang-2015-The MADS-box transcription factor Fg,Batch045B,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4965,PHI:4515,UniProt,P24417,GenBank,CAA40047,,,Dublin,vsdA,,,,,,,28901,Salmonella enterica,98360,subsp. enterica serovar Dublin strain Lane,salmonellosis (cattle),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,virulence related genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,2041471,PubMed,10.1111/j.1365-2958.1991.tb02111.x,Mol Microbiol. 1991 Feb;5(2):307-16,,,M Krause 1991,1991,4 genes,Krause-1991-Molecular analysis of the virulenc,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4966,PHI:4516,UniProt,P24419,GenBank,CAA40049,,,Dublin,vsdC,,,,,,,28901,Salmonella enterica,98360,subsp. enterica serovar Dublin strain Lane,salmonellosis (cattle),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,virulence related genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,2041471,PubMed,10.1111/j.1365-2958.1991.tb02111.x,Mol Microbiol. 1991 Feb;5(2):307-16,,,M Krause 1991,1991,4 genes,Krause-1991-Molecular analysis of the virulenc,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4967,PHI:4517,UniProt,P0A2N0,GenBank,CAA40050,,,Dublin,vsdD,,,,,,,28901,Salmonella enterica,98360,subsp. enterica serovar Dublin strain Lane,salmonellosis (cattle),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,virulence related genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,2041471,PubMed,10.1111/j.1365-2958.1991.tb02111.x,Mol Microbiol. 1991 Feb;5(2):307-16,,,M Krause 1991,1991,4 genes,Krause-1991-Molecular analysis of the virulenc,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4968,PHI:4518,UniProt,P0A2N3,GenBank,CAA40051,,,Dublin,vsdE,,,,,,,28901,Salmonella enterica,98360,subsp. enterica serovar Dublin strain Lane,salmonellosis (cattle),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,virulence related genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,2041471,PubMed,10.1111/j.1365-2958.1991.tb02111.x,Mol Microbiol. 1991 Feb;5(2):307-16,,,M Krause 1991,1991,4 genes,Krause-1991-Molecular analysis of the virulenc,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4969,PHI:4519,UniProt,E5AD52,GenBank,CBY02404,,,JN3,LmStuA,,,,,,,5022,Leptosphaeria maculans,,v23.1.3,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),,,,leaf,APSES transcription factor,,,,loss of pathogenicity,yes,,,,,reduced,,reduced; aberrant,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25727237,PubMed,10.1111/mpp.12249,Mol Plant Pathol. 2015 Feb 24,Isabelle.Fudal@versailles.inra.fr,,J L Soyer 2015,2015,1 gene,Soyer-2015-The APSES transcription factor LmSt,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4970,PHI:4520,UniProt,K9FRJ5,GenBank,EKV12295,,,PHI26,PdMit1,,,,,,,36651,Penicillium digitatum,,PdKH8,green mold (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),,,,fruit,MIPC synthase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,reduced,no,CaCl2,CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,RP,25725383,PubMed,10.1016/j.resmic.2015.02.001,Res Microbiol. 2015 Feb 26. pii: S0923-2508(15)00028-5,hyli@zju.edu.cn,,C Zhu 2015,2015,1 gene,"Zhu-2015-Deletion of PdMit1, a homolog of yeas",BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4971,PHI:4521,UniProt,G7TEN8,GenBank,AEQ96403,,,BLS256,rpfF,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,diffusible signal factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25656587,PubMed,10.1111/mmi.12965,Mol Microbiol. 2015 Feb 6,subhadeep@cdfd.org.in,The DSF deficient mutant of X. oryzaepv. oryzicolaexhibited a reduced capacity to use ferric form of iron for growth under low-iron conditions.,R Rai 2015,2015,1 gene,Rai-2015-Cell-cell signaling promotes ferric i,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4972,PHI:4522,UniProt,F4MD93,GenBank,AEE60090,,,UMNK88,HlyA,,,,,,,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,urinary bladder,induces caspase-1/caspase-4-dependent inflammatory cell death in human urothelial cells,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25675528,PubMed,10.1073/pnas.1500374112,Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):E871-80,hultgren@wusm.wustl.edu,,K Nagamatsu 2015,2015,2 genes,Nagamatsu-2015-Dysregulation of Escherichia co,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4973,PHI:4523,UniProt,P0AE88,GenBank,AAC36868,,,L547,CpxR,,,,,,,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,urinary bladder,response regulator (CpxR)-sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25675528,PubMed,10.1073/pnas.1500374112,Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):E871-80,hultgren@wusm.wustl.edu,,K Nagamatsu 2015,2015,2 genes,Nagamatsu-2015-Dysregulation of Escherichia co,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4974,PHI:4522,UniProt,F4MD93,GenBank,AEE60090,,,UMNK88,HlyA,,,,,,,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,urinary bladder,induces caspase-1/caspase-4-dependent inflammatory cell death in human urothelial cells,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25675528,PubMed,10.1073/pnas.1500374112,Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):E871-80,hultgren@wusm.wustl.edu,,K Nagamatsu 2015,2015,2 genes,Nagamatsu-2015-Dysregulation of Escherichia co,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4975,PHI:4524,UniProt,Q8YF74,GenBank,AAL52829,,,16M,RegM,chromosome 1,deltaregM::km,,,,,29459,Brucella melitensis,224914,16M,infertility; spontaneous abortion,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,encoding a sensory transduction protein kinase,,,,unaffected pathogenicity,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: partial; gene complementation,,,RP,25648428,PubMed,10.1007/s00284-015-0782-1,Curr Microbiol. 2015 Feb 4.,wuqm@cau.edu.cn,The mutant was less able to withstand acid and hyperosmotic conditions than wild-type strain but shown no significant difference with wild-type strain when challenged by elevated temperature and hypotonic conditions.,H Dong 2015,2015,1 gene,Dong-2015-The Effects of RegM on Stress Respon,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4976,PHI:4525,UniProt,X5FD66,GenBank,AHW84468,,,UK7,PFP1,,UK7deltaPFP1,,,,,914237,Rhynchosporium commune,,UK7,scald,monocots,4513,Hordeum vulgare (related: barley),cv. Ingrid,,,leaf,encoding an Epc-N domain-containing protein,,,,reduced virulence,,,,,,,,wild type,reduced,no,,,,,,,gene mutation; gene complementation,,,RP,24906413,PubMed,10.1128/EC.00043-14,Eukaryot Cell. 2014 Aug;13(8):1026-35,wknogge@ipb-halle.de,,S Siersleben 2014,2014,1 gene,"Siersleben-2014-PFP1, a gene encoding an Epc-N",BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4977,PHI:4526,UniProt,G4NJP7,GenBank,MGG_12654,,,70-15,AvrPi9,chromosome 7,,,,,,318829,Magnaporthe oryzae,,R88-002,blast (rice),monocots,4530,Oryza sativa (related: rice),IR31917 line,,,leaf,plant avirulence gene,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25659573,PubMed,10.1111/nph.13310,New Phytol. 2015 Feb 6,b.zhou@irri.org,,J Wu 2015,2015,1 gene,Wu-2015-Comparative genomics identifies the Ma,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4978,PHI:4527,,no data found,,MLP102036,,,98AG31,MLP102036,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4979,PHI:4528,,no data found,,MLP105684,,,98AG31,MLP105684,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4980,PHI:4529,,no data found,,MLP106985,,,98AG31,MLP106985,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4981,PHI:4530,,no data found,,MLP107772,,,98AG31,MLP107772,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4982,PHI:4531,,no data found,,MLP109567,,,98AG31,MLP109567,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4983,PHI:4532,,no data found,,MLP123227,,,98AG31,MLP123227,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4984,PHI:4533,,no data found,,MLP123524,,,98AG31,MLP123524,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4985,PHI:4534,,no data found,,MLP123532,,,98AG31,MLP123532,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4986,PHI:4535,,no data found,,MLP123731,,,98AG31,MLP123731,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4987,PHI:4536,,no data found,,MLP124017,,,98AG31,MLP124017,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4988,PHI:4537,,no data found,,MLP124111,,,98AG31,MLP124111,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4989,PHI:4538,,no data found,,MLP124266,,,98AG31,MLP124266,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4990,PHI:4539,,no data found,,MLP124353,,,98AG31,MLP124353,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4991,PHI:4540,,no data found,,MLP124371,,,98AG31,MLP124371,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4992,PHI:4541,,no data found,,MLP124478,,,98AG31,MLP124478,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4993,PHI:4542,,no data found,,MLP124497,,,98AG31,MLP124497,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4994,PHI:4543,,no data found,,MLP124499,,,98AG31,MLP124499,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4995,PHI:4544,,no data found,,MLP124530,,,98AG31,MLP124530,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4996,PHI:4545,,no data found,,MLP124543,,,98AG31,MLP124543,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4997,PHI:4546,,no data found,,MLP124561,,,98AG31,MLP124561,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4998,PHI:4547,,no data found,,MLP37347,,,98AG31,MLP37347,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 4999,PHI:4548,,no data found,,MLP64894,,,98AG31,MLP64894,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5000,PHI:4549,,no data found,,MLP67606,,,98AG31,MLP67606,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5001,PHI:4550,,no data found,,MLP91075,,,98AG31,MLP91075,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens GV3101,,RP,25650830,PubMed,10.1094/MPMI-01-15-0003-R,Mol Plant Microbe Interact. 2015 Feb 4,Sophien.Kamoun@tsl.ac.uk,,B Petre 2015,2015,24 genes,Petre-2015-Candidate Effector Proteins of the,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5002,PHI:4551,,no data found,GenBank,KM078599,,,GJ33,FaTuA1,,,,,,,282267,Fusarium asiaticum,,GJ33,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spike,a-tubulins,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,carbendazim,"carbendazim: CHEBI:3392, CAS:10605-21-7",,,,,gene disruption; gene complementation,,,RP,25660319,PubMed,10.1016/j.resmic.2015.01.001,Res Microbiol. 2015 Feb 7. pii: S0923-2508(15)00014-5,ynyin@zju.edu.cn,FaTuA2 mutant showed increased sensitivity to carbendazim,W Hu 2015,2015,2 genes,Hu-2015-alpha1-Tubulin FaTuA1 plays crucial ro,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5003,PHI:4552,,no data found,GenBank,KM078600,,,GJ33,FaTUA2,,,,,,,282267,Fusarium asiaticum,,GJ33,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spike,a-tubulins,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,carbendazim,"carbendazim: CHEBI:3392, CAS:10605-21-7",,,,,gene disruption; gene complementation,,,RP,25660319,PubMed,10.1016/j.resmic.2015.01.001,Res Microbiol. 2015 Feb 7. pii: S0923-2508(15)00014-5,ynyin@zju.edu.cn,FaTuA2 mutant showed increased sensitivity to carbendazim,W Hu 2015,2015,2 genes,Hu-2015-alpha1-Tubulin FaTuA1 plays crucial ro,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5004,PHI:4553,UniProt,Q0Q5C2,GenBank,ABG21287,,,GAR,FhbA,,YORdeltafhbA,,Factor H,UniProt: P06909,,140,Borrelia hermsii,1293576,YOR,tick-borne relapsing fever,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,blood,factor H binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24866803,PubMed,10.1128/IAI.01892-14,Infect Immun. 2014 Aug;82(8):3324-32,rmarconi@vcu.edu,YOR fhbAstrain remained infectious in mice and retained resistance to killingin vitroby human complement,L M Fine 2015,2015,1 gene,Fine-2014-The Borrelia hermsii factor H bindin,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5005,PHI:4554,UniProt,E9EPV1,GenBank,EFZ02154,,,ARSEF 23,MBZ1,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bZip transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25673695,PubMed,10.1074/jbc.M114.630939,J Biol Chem. 2015 Feb 10,cswang@sibs.ac.cn,"While the mutant conidia do develop normal appresoria, the inability to attach to the host is what perhaps causes the reduced virulence.",W Huang 2015,2015,1 gene,Huang-2015-Regulation of bZIP transcription fa,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5006,PHI:4555,UniProt,A0A095EN78,GenBank,KGB78493,,,R265,URE1,,,,,,,552467,Cryptococcus bacillisporus,294750,R265,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; blood,urease,,,,reduced virulence,,,,,,,,,,no,acetohydroxamic acid (AHA),acetohydroxamic acid (AHA): CHEBI:27777,,,,,gene disruption; gene complementation,,,RP,25675897,PubMed,10.1111/febs.13229,FEBS J. 2015 Feb 9,mhv@cbiot.ufrgs.br,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,V Feder 2015,2015,3 genes,Feder-2015-Cryptococcus gattii urease as a vir,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5007,PHI:4556,UniProt,A0A095C2M1,GenBank,KGB74897,,,R265,Ure4,,,,,,,552467,Cryptococcus bacillisporus,294750,R265,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; blood,urease,,,,reduced virulence,,,,,,,,,,no,acetohydroxamic acid (AHA),acetohydroxamic acid (AHA): CHEBI:27777,,,,,gene disruption; gene complementation,,,RP,25675897,PubMed,10.1111/febs.13229,FEBS J. 2015 Feb 9,mhv@cbiot.ufrgs.br,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,V Feder 2015,2015,3 genes,Feder-2015-Cryptococcus gattii urease as a vir,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5008,PHI:4557,UniProt,A0A095CJ15,GenBank,KGB79369,,,R265,Ure6,,,,,,,552467,Cryptococcus bacillisporus,294750,R265,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; blood,urease,,,,unaffected pathogenicity,,,,,,,,,,no,acetohydroxamic acid (AHA),acetohydroxamic acid (AHA): CHEBI:27777,,,,,gene disruption; gene complementation,,,RP,25675897,PubMed,10.1111/febs.13229,FEBS J. 2015 Feb 9,mhv@cbiot.ufrgs.br,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,V Feder 2015,2015,3 genes,Feder-2015-Cryptococcus gattii urease as a vir,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5009,PHI:4558,UniProt,X5FDR6,GenBank,KF678349,,,TW-XM,T6SS1,,deltaVgrG-T6SS1,,,,PHI:4560,562,Escherichia coli,,TW-XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,brain,type VI secretion systems (T6SSs) effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24980972,PubMed,10.1128/IAI.01769-14,Infect Immun. 2014 Sep;82(9):3867-79,yaohch@njau.edu.cn,,J Ma 2014,2014,3 genes,Ma-2014-Two functional type VI secretion syste,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5010,PHI:4559,UniProt,Q6TKU1,GenBank,KF678350,,,TW-XM,T6SS2,,deltaVgrG-T6SS2,,,,PHI:4560,562,Escherichia coli,,TW-XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,brain,type VI secretion systems (T6SSs) effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24980972,PubMed,10.1128/IAI.01769-14,Infect Immun. 2014 Sep;82(9):3867-79,yaohch@njau.edu.cn,,J Ma 2014,2014,3 genes,Ma-2014-Two functional type VI secretion syste,BATCH_046A,2015-03-01,MC,,,,,,,,,,,,,
,,Record 5011,PHI:4560,UniProt,D3QWN3,GenBank,ADD54889,,,CB9615,VgrG,,,,,,,562,Escherichia coli,,TW-XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,brain,type VI secretion systems (T6SSs) effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24980972,PubMed,10.1128/IAI.01769-14,Infect Immun. 2014 Sep;82(9):3867-79,yaohch@njau.edu.cn,,J Ma 2014,2014,3 genes,Ma-2014-Two functional type VI secretion syste,BATCH_046A,2015-03-15,MC,,,,,,,,,,,,,
,,Record 5012,PHI:3668,UniProt,D0ZLQ7,GenBank,AAD16960,,,14028s,MgtC,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,food poisoning,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,virulence protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,23827679,PubMed,10.1016/j.cell.2013.06.004,,eduardo.groisman@yale.edu,,E-J Lee 2013,2013,1 gene,Lee-2013-A bacterial virulenc,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5013,PHI:3669,UniProt,H9B3V9,GenBank,KC305711,,,Vd8,VdATG8,,,,,,,27337,Verticillium dahliae,,Vd8,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root,autophagy,,,,unaffected pathogenicity,,no,,,,reduced,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,23969251,PubMed,10.1016/j.jgg.2013.04.006,,cotton@njau.edu.cn,,L Zhou 2013,2013,2 genes,Zhou-2013-Functional Analysis,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5014,PHI:3670,UniProt,M4Q9U3,GenBank,KC305712,,,Vd8,VdATG12,,,,,,,27337,Verticillium dahliae,,Vd8,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root,autophagy,,,,unaffected pathogenicity,,no,,,,reduced,,increased,,no,,,,,,,gene disruption; gene complementation,,,RP,23969251,PubMed,10.1016/j.jgg.2013.04.006,,cotton@njau.edu.cn,,L Zhou 2013,2013,2 genes,Zhou-2013-Functional Analysis,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5015,PHI:3671,UniProt,Q9X3T0,GenBank,AF083877_4,,,Ea321,hrpS,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5016,PHI:3672,UniProt,D4IAW2,GenBank,CBJ47568,,,ATCC 49946,hrpL,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5017,PHI:3673,UniProt,D4HUY5,GenBank,CBA19258,,,CFBP1430,rpoN,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,a nitrogen limitation sigma factor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5018,PHI:3674,UniProt,D4HUY4,GenBank,CBA19257,,,CFBP1430,yhbH,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,a novel ribosome-associated modulation protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5019,PHI:3675,UniProt,D4HX89,GenBank,CBA19780,,,CFBP1430,yfiA,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5020,PHI:3676,UniProt,D4I0C5,GenBank,CBA20332,,,CFBP1430,rmf3,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5021,PHI:3677,UniProt,Q9X3T0,GenBank,AF083877_4,,,Ea321,hrpS,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5022,PHI:3678,UniProt,D4IAW2,GenBank,CBJ47568,,,ATCC 49946,hrpL,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5023,PHI:3679,UniProt,D4HUY5,GenBank,CBA19258,,,CFBP1430,rpoN,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,a nitrogen limitation sigma factor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5024,PHI:3680,UniProt,D4HUY4,GenBank,CBA19257,,,CFBP1430,yhbH,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,a novel ribosome-associated modulation protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5025,PHI:3681,UniProt,D4HX89,GenBank,CBA19780,,,CFBP1430,yfiA,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5026,PHI:3682,UniProt,D4I0C5,GenBank,CBA20332,,,CFBP1430,rmf3,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23937726,PubMed,10.1111/mpp.12065,,zhao888@illinois.edu,,V ANCONA 2013,2013,6 genes,Ancona-2013-Alternative sigma fa,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5027,PHI:3683,UniProt,Q97RW0,GenBank,AAK74821,,,TIGR4,SP_0676,,,,,,,1313,Streptococcus pneumoniae,,WCH43,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung blood; brain,transcription facot,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,23967124,PubMed,10.1371/journal.pone.0070862,,david.gunniyi@adelaide.edu.au,,L K Mahdi 2013,2013,2 genes,Mahdi-2013-A Transcription Fact,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5028,PHI:3683,UniProt,Q97RW0,GenBank,AAK74821,,,TIGR4,SP_0676,,,,,,,1313,Streptococcus pneumoniae,,WCH16,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung blood; brain,transcription facot,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,23967124,PubMed,10.1371/journal.pone.0070862,,david.gunniyi@adelaide.edu.au,,L K Mahdi 2013,2013,2 genes,Mahdi-2013-A Transcription Fact,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5029,PHI:3684,UniProt,Q97R98,GenBank,AAK75051,,,TIGR4,SP_0927,,,,,,,1313,Streptococcus pneumoniae,,WCH43,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung blood; brain,transcription facot,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,23967124,PubMed,10.1371/journal.pone.0070862,,david.gunniyi@adelaide.edu.au,,L K Mahdi 2013,2013,2 genes,Mahdi-2013-A Transcription Fact,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5030,PHI:3684,UniProt,Q97R98,GenBank,AAK75051,,,TIGR4,SP_0927,,,,,,,1313,Streptococcus pneumoniae,,WCH16,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung blood; brain,transcription facot,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,23967124,PubMed,10.1371/journal.pone.0070862,,david.gunniyi@adelaide.edu.au,,L K Mahdi 2013,2013,2 genes,Mahdi-2013-A Transcription Fact,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5031,PHI:3685,UniProt,L0T4N0,GenBank,CCP42923,,,H37Rv,Rv0195,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,LuxR family transcription factor gene,,,,reduced virulence,,,,,,,,wild type,,no,,vitamin C: CHEBI:21241,,,,,gene deletion: full; gene complementation,,,RP,23673208,PubMed,10.1016/j.tube.2013.04.005,,lichuanyou6688@hotmail.com,The deletion also reduced intracellular survivability under hypoxic and reductive stress triggered by vitamin C,H Fang 2013,2013,1 gene,Fang-2013-The LuxR family regu,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5032,PHI:3686,UniProt,Q06131,GenBank,AAA72322,,,YPIII(pIB1),yopD,,,,,,,633,Yersinia pseudotuberculosis,502800,YPIII/pIB102,acute enteric disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,mesenteric lymph node; spleen,type III secretion,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23279117,PubMed,10.1111/cmi.12100,,matthew.francis@molbiol.umu.se,,T R D Costa 2013,2013,1 gene,Costa-2013-Type III secretion t,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5033,PHI:3687,UniProt,Q5AAG9,GenBank,EAK99762,,,SC5314,Pot1p,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,egg,3-ketoacyl-CoA thiolases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23758791,PubMed,10.1111/1567-1364.12057,,Matthias.brock@hki-jena.de,,C Otzen 2013,2013,3 genes,Otzen-2013-Phylogenetic and phe,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5034,PHI:3688,UniProt,Q5AJ90,GenBank,EAL02864,,,SC5314,Fox3p,chromosome 3,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,egg,3-ketoacyl-CoA thiolases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23758791,PubMed,10.1111/1567-1364.12057,,Matthias.brock@hki-jena.de,,C Otzen 2013,2013,3 genes,Otzen-2013-Phylogenetic and phe,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5035,PHI:3689,UniProt,Q5AD21,GenBank,EAL00612,,,SC5314,Pot13p,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,egg,3-ketoacyl-CoA thiolases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23758791,PubMed,10.1111/1567-1364.12057,,Matthias.brock@hki-jena.de,,C Otzen 2013,2013,3 genes,Otzen-2013-Phylogenetic and phe,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5036,PHI:3690,UniProt,Q5AGA0,GenBank,EAL01751,,,SC5314,Mnn1,chromosome 5,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"predicted to act as alpha-1 ,3 mann osyltransferases",,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white; Congo red; SDS; hygromycin B; NaCl; tunicamycin,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; hygromycin B: CHEBI:16976; NaCl: CHEBI:26710; tunicamycin: CHEBI:29699,,,,,gene deletion: full,,,RP,23886038,PubMed,10.1186/1756-0500-6-294,,s.bates@ex.ac.uk,"Only the mnn14 delta null mutant displayed hypersensitivity to agents associated with cell wall and glycosylation defects, suggesting an altered cell wall structure.",S Bates 2013,2013,6 genes,Bates-2013-Role of the Candida,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5037,PHI:3691,UniProt,Q5APQ8,GenBank,EAL04888,,,SC5314,Mnn12,chromosome 1,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"predicted to act as alpha-1 ,3 mann osyltransferases",,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white; Congo red; SDS; hygromycin B; NaCl; tunicamycin,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; hygromycin B: CHEBI:16976; NaCl: CHEBI:26710; tunicamycin: CHEBI:29699,,,,,gene deletion: full,,,RP,23886038,PubMed,10.1186/1756-0500-6-294,,s.bates@ex.ac.uk,"Only the mnn14 delta null mutant displayed hypersensitivity to agents associated with cell wall and glycosylation defects, suggesting an altered cell wall structure.",S Bates 2013,2013,6 genes,Bates-2013-Role of the Candida,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5038,PHI:3692,UniProt,Q5AGA9,GenBank,EAL01742,,,SC5314,Mnn13,chromosome 5,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"predicted to act as alpha-1 ,3 mann osyltransferases",,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white; Congo red; SDS; hygromycin B; NaCl; tunicamycin,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; hygromycin B: CHEBI:16976; NaCl: CHEBI:26710; tunicamycin: CHEBI:29699,,,,,gene deletion: full,,,RP,23886038,PubMed,10.1186/1756-0500-6-294,,s.bates@ex.ac.uk,"Only the mnn14 delta null mutant displayed hypersensitivity to agents associated with cell wall and glycosylation defects, suggesting an altered cell wall structure.",S Bates 2013,2013,6 genes,Bates-2013-Role of the Candida,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5039,PHI:3693,UniProt,Q59YS7,GenBank,EAK95655,,,SC5314,Mnn14,chromosome 3,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"predicted to act as alpha-1 ,3 mann osyltransferases",,,,reduced virulence,,,,,,,,reduced; aberrant,,no,calcofluor white; Congo red; SDS; hygromycin B; NaCl; tunicamycin,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; hygromycin B: CHEBI:16976; NaCl: CHEBI:26710; tunicamycin: CHEBI:29699,,,,,gene deletion: full,,,RP,23886038,PubMed,10.1186/1756-0500-6-294,,s.bates@ex.ac.uk,"Only the mnn14 delta null mutant displayed hypersensitivity to agents associated with cell wall and glycosylation defects, suggesting an altered cell wall structure.",S Bates 2013,2013,6 genes,Bates-2013-Role of the Candida,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5040,PHI:3694,UniProt,Q59VI0,GenBank,EAK94458,,,SC5314,Mnn15,chromosome 1,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"predicted to act as alpha-1 ,3 mann osyltransferases",,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white; Congo red; SDS; hygromycin B; NaCl; tunicamycin,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; hygromycin B: CHEBI:16976; NaCl: CHEBI:26710; tunicamycin: CHEBI:29699,,,,,gene deletion: full,,,RP,23886038,PubMed,10.1186/1756-0500-6-294,,s.bates@ex.ac.uk,"Only the mnn14 delta null mutant displayed hypersensitivity to agents associated with cell wall and glycosylation defects, suggesting an altered cell wall structure.",S Bates 2013,2013,6 genes,Bates-2013-Role of the Candida,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5041,PHI:3695,UniProt,Q59MZ9,GenBank,EAK91859,,,SC5314,Mnn16,,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"predicted to act as alpha-1 ,3 mann osyltransferases",,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white; Congo red; SDS; hygromycin B; NaCl; tunicamycin,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; hygromycin B: CHEBI:16976; NaCl: CHEBI:26710; tunicamycin: CHEBI:29699,,,,,gene deletion: full,,,RP,23886038,PubMed,10.1186/1756-0500-6-294,,s.bates@ex.ac.uk,"Only the mnn14 delta null mutant displayed hypersensitivity to agents associated with cell wall and glycosylation defects, suggesting an altered cell wall structure.",S Bates 2013,2013,6 genes,Bates-2013-Role of the Candida,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5042,PHI:3696,UniProt,M4JRM2,GenBank,AGC88581,,,APEC O78,EnvZ-OmpR,,,,,,,562,Escherichia coli,679895,BW25113,colibacillosis; cellulitis; swollen head syndrome,flies,7227,Drosophila melanogaster (related: fruit fly),Oregon R,,,,two-component regulatory system,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23886953,PubMed,10.1016/j.bbrc.2013.07.062,,ashira@staff.kanazawa-u.ac.jp,,P Pukklay 2013,2013,1 gene,Pukklay-2013-Involvement of EnvZ-,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5043,PHI:3697,UniProt,I1RL06,GenBank,XM_384756,,,PH-1,FgABC1,,,,,,,5518,Fusarium graminearum,,CS3005,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kennedy,,,root,ABC pleiotropic drug resistance transporter,,,,reduced virulence,,,,,,,,,,no,benalaxyl; gramine; 2-benzoxazalinone; tryptamine,tryptamine: CHEBI:16765,,,,,gene deletion: full,,,RP,23965171,PubMed,10.1111/1574-6968.12240,,donald.gardiner@csi ro.au,"Deletion of FgABC1 also led to increased sen-sitivity of the fungus to the antifungal compound benalaxyl in culture,to gramine, 2-benzoxazalinone and tryptamine was unaltered.",D M Gardiner 2013,2013,1 gene,Gardiner-2013-An ABC pleiotropic d,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5044,PHI:3698,UniProt,Q9KI30,GenBank,AF244083_1,,,,eseH,,,,,,,67780,Edwardsiella ictaluri,,HSN-1,enteric septicemia,bony fishes,7998,Ictalurus punctatus (related: channel catfish),,,,liver; spleen,plasmid-encoded protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23850444,PubMed,10.1016/j.vetmic.2013.05.023,,pinnie@ihb.ac.cn,,L J Zhao 2013,2013,3 genes,Zhao-2013-Roles of plasmid-enc,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5045,PHI:3699,UniProt,Q9KI25,GenBank,AF244084_1,,,,escD,,,,,,,67780,Edwardsiella ictaluri,,HSN-1,enteric septicemia,bony fishes,7998,Ictalurus punctatus (related: channel catfish),,,,liver; spleen,plasmid-encoded protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23850444,PubMed,10.1016/j.vetmic.2013.05.023,,pinnie@ihb.ac.cn,,L J Zhao 2013,2013,3 genes,Zhao-2013-Roles of plasmid-enc,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5046,PHI:3700,UniProt,M1L5E8,GenBank,AGF34188,,,,eseI,,,,,,,67780,Edwardsiella ictaluri,,HSN-1,enteric septicemia,bony fishes,7998,Ictalurus punctatus (related: channel catfish),,,,liver; spleen,plasmid-encoded protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23850444,PubMed,10.1016/j.vetmic.2013.05.023,,pinnie@ihb.ac.cn,,L J Zhao 2013,2013,3 genes,Zhao-2013-Roles of plasmid-enc,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5047,PHI:3701,UniProt,Q52B93,GenBank,EHA53981,,,70-15,PacC,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sariceltik,,,leaf,pH response transription factor,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23874922,PubMed,10.1371/journal.pone.0069236,,christophe.bruel@univ-lyon1.fr,,P Landraud 2013,2013,1 gene,Landraud-2013-Adaptation to pH and,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5048,PHI:3701,UniProt,Q52B93,GenBank,EHA53981,,,70-15,PacC,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,pH response transription factor,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23874922,PubMed,10.1371/journal.pone.0069236,,christophe.bruel@univ-lyon1.fr,,P Landraud 2013,2013,1 gene,Landraud-2013-Adaptation to pH and,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5049,PHI:3701,UniProt,Q52B93,GenBank,EHA53981,,,70-15,PacC,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Maratelli,,,leaf,pH response transription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23874922,PubMed,10.1371/journal.pone.0069236,,christophe.bruel@univ-lyon1.fr,,P Landraud 2013,2013,1 gene,Landraud-2013-Adaptation to pH and,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5050,PHI:3701,UniProt,Q52B93,GenBank,EHA53981,,,70-15,PacC,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,pH response transription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23874922,PubMed,10.1371/journal.pone.0069236,,christophe.bruel@univ-lyon1.fr,,P Landraud 2013,2013,1 gene,Landraud-2013-Adaptation to pH and,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5051,PHI:3702,UniProt,B2RM93,GenBank,BAG34488,,,ATCC 33277,RgpA,,,,,,,837,Porphyromonas gingivalis,242619,W83,periodontitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,jaw,arginine-specific cysteine proteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23909600,PubMed,10.1111/jcpe.12139,,,hemi-maxillae (upper jaw bone),A Wilensky 2013,2013,1 gene,Wilensky-2013-The role of RgpA in,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5052,PHI:3703,UniProt,G3F417,GenBank,AEN19352,,,Clinton 1b,fvtox1,,,,,,,232082,Fusarium virguliforme,994087,Mont-1,sudden death syndrome,eudicots,3847,Glycine max (related: soybean),cv. Williams 82,,,root; leaf,toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23702608,PubMed,10.1007/s00294-013-0392-z,,mbhattac@iastate.edu,,R N Pudake 2013,2013,1 gene,Pudake-2013-Investigation of the,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5053,PHI:3704,UniProt,P12061,GenBank,AAA27219,,,3B,SEF14,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain 50336,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,fimbrial protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23933167,PubMed,10.1016/j.micpath.2013.07.002,,yzgqzhu@hotmail.com,,C Zhu 2013,2013,1 gene,Zhu-2013-SEF14 fimbriae from,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5054,PHI:3705,UniProt,P0A3S3,GenBank,CAA38134,,,,endA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,membrane surface localized endonuclease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23936195,PubMed,10.1371/journal.pone.0070363,,geelau@i llinois.edu,,L Zhu 2013,2013,1 gene,Zhu-2013-Competence-independe,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5055,PHI:3706,UniProt,S6G070,GenBank,CDG32266,,,Vl43,VlCPC1-1,,,,,,,100787,Verticillium longisporum,,Vl43,early senescence; early ripening,eudicots,3708,Brassica napus (related: rape),,,,seedling,cross pathway control gene in amino acid pathway,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23883358,PubMed,10.1094/MPMI-06-13-0181-R,,gbraus@gwdg.d,Should this have once accession or two- not sure.. These are isogenes. Guidelines say give each allele an ID (AC 18Mar2015),C Timpner 2013,2013,2 genes,Timpner-2013-The Cpc1 regulator o,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5056,PHI:3707,UniProt,S6G070,GenBank,CDG32266,,,Vl43,VlCPC1-2,,,,,,,100787,Verticillium longisporum,,Vl43,early senescence; early ripening,eudicots,3708,Brassica napus (related: rape),,,,seedling,cross pathway control gene in amino acid pathway,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23883358,PubMed,10.1094/MPMI-06-13-0181-R,,gbraus@gwdg.d,Should this have once accession or two- not sure.. These are isogenes. Guidelines say give each allele an ID (AC 18Mar2015),C Timpner 2013,2013,2 genes,Timpner-2013-The Cpc1 regulator o,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5057,PHI:3706,UniProt,S6G070,GenBank,CDG32266,,,Vl43,VlCPC1-1,,,,,,,100787,Verticillium longisporum,,Vl43,early senescence; early ripening,eudicots,4081,Solanum lycopersicum (related: tomato),,,,seedling,cross pathway control gene in amino acid pathway,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23883358,PubMed,10.1094/MPMI-06-13-0181-R,,gbraus@gwdg.d,Should this have once accession or two- not sure.. These are isogenes. Guidelines say give each allele an ID (AC 18Mar2015),C Timpner 2013,2013,2 genes,Timpner-2013-The Cpc1 regulator o,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5058,PHI:3707,UniProt,S6G070,GenBank,CDG32266,,,Vl43,VlCPC1-2,,,,,,,100787,Verticillium longisporum,,Vl43,early senescence; early ripening,eudicots,4081,Solanum lycopersicum (related: tomato),,,,seedling,cross pathway control gene in amino acid pathway,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23883358,PubMed,10.1094/MPMI-06-13-0181-R,,gbraus@gwdg.d,Should this have once accession or two- not sure.. These are isogenes. Guidelines say give each allele an ID (AC 18Mar2015),C Timpner 2013,2013,2 genes,Timpner-2013-The Cpc1 regulator o,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5059,PHI:3708,UniProt,G2XBR1,GenBank,EGY16533,,,VdLs.17,VdSSP1,,,,,,,27337,Verticillium dahliae,1027910,VDG1,wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted protein gene,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23891822,PubMed,10.1016/j.gene.2013.06.089,,daixiaofeng@caas.cn,The deletion mutants fungal growth decreased in media with pectinand starch as carbon sources.,S-Y Liu 2013,2013,1 gene,Liu-2013-Molecular characteri,Batch031,2013-09-01,MC,,,,,,,,,,,,,
,,Record 5060,PHI:3709,UniProt,J7KWB2,GenBank,AFR05658,,,PCC21,qseC,,,,,,,554,Pectobacterium carotovorum,1218933,subsp. carotovorum strain Pcc21,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,,sensor protein QseC bacterial adrenergic receptor,,,,reduced virulence,,,,,,,,reduced,,no,berberine; rhein; genistein,berberine: CHEBI:16118; genistein: CHEBI:28088,,,,,gene mutation; gene complementation,,,RP,23676432,PubMed,10.1099/mic.0.067280-0,,sunggiheu@korea.kr,"Of the mutants, only the tolC mutant showed increased sensitivity to half of the plant-derived chemicals",D H Lee 2013,2013,3 genes,Lee-2013-Characterization of,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5061,PHI:3710,UniProt,C6DB00,GenBank,ACT12042,,,PC1,tolC,,,,,,,554,Pectobacterium carotovorum,1218933,subsp. carotovorum strain Pcc21,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,,outer membrane channel protein,,,,reduced virulence,,,,,,,,,,no,berberine; rhein; genistein,berberine: CHEBI:16118; genistein: CHEBI:28088,,,,,gene mutation; gene complementation,,,RP,23676432,PubMed,10.1099/mic.0.067280-0,,sunggiheu@korea.kr,"Of the mutants, only the tolC mutant showed increased sensitivity to half of the plant-derived chemicals",D H Lee 2013,2013,3 genes,Lee-2013-Characterization of,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5062,PHI:3711,UniProt,J7KWZ6,GenBank,AFR03725,,,PCC21,PCC21 _023220,,,,,,,554,Pectobacterium carotovorum,1218933,subsp. carotovorum strain Pcc21,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,,putative DNA-binding protein,,,,reduced virulence,,,,,,,,,,no,berberine; rhein; genistein,berberine: CHEBI:16118; genistein: CHEBI:28088,,,,,gene mutation; gene complementation,,,RP,23676432,PubMed,10.1099/mic.0.067280-0,,sunggiheu@korea.kr,"Of the mutants, only the tolC mutant showed increased sensitivity to half of the plant-derived chemicals",D H Lee 2013,2013,3 genes,Lee-2013-Characterization of,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5063,PHI:3712,UniProt,Q59US7,GenBank,EAK94207,,,SC5314,Ecm7,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,"regulator of HACS, functions in calcium homeostasis maintenance, oxidative stress response and hyphal development in Candida albicans",,,,unaffected pathogenicity,,,,yes,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,23769872,PubMed,10.1016/j.fgb.2013.05.010,,nklimingchun@163.com,Mutants sensitive to H2O2,X Ding 2013,2013,1 gene,"Ding-2013-Ecm7, a regulator of",Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5064,PHI:3713,UniProt,Q97R47,GenBank,AAK75106,,,TIGR4,GHIP,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),TIGR4,,,nasal cavity; lung; blood,glycosy l hydrolase,,,,unaffected pathogenicity,,,,yes,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23874703,PubMed,10.1371/journal.pone.0068647,,wangd@ustc.edu,,S Niu 2013,2013,1 gene,Niu-2013-Structural Basis of,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5065,PHI:3714,UniProt,C8TZQ2,GenBank,BAI33414,,,O103:H2 str. 12009,OxyR,,,,,,,562,Escherichia coli,,UCB34 (O17:K+:H18),urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney,oxidative stress response regulator,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,23850958,PubMed,10.1016/j.micpath.2013.07.001,,drawz007@umn.edu,the isogenic oxyR mutant exhibited increased H2O2 sensitivity,J R Johnson 2013,2013,1 gene,Johnson-2013-OxyR contributes to,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5066,PHI:3715,UniProt,C1KVQ1,GenBank,CAS05376,,,CLIP 80459,prx,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,protection against reactive oxygen intermediates (ROI) and reactive nitrogen intermediates (RNI),,,,reduced virulence,,,,,,,,wild type,,no,hydrogen peroxide; cumene hydroperoxide; S-nitroso-N-acetylpenicillamine (SNAP); 3-morpholinosydnonimine hydrochloride (SIN-1),H2O2: CHEBI:16240,,,,,gene mutation,,,RP,23929591,PubMed,10.1111/2049-632X.12081,,ldo@sund.ku.dk,"The deltaprx mutant had increased sensitivity to hydrogen peroxide, cumene hydroperoxide,nitric oxide-generating compound S-nitroso-N-acetylpenicillamine (SNAP) and 3-morpholinosydnonimine hydrochloride (SIN-1), a peroxynitrite donor compared to the wild-type strain.",L E Dons 2013,2013,1 gene,Dons-2013-Role of the Listeria,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5067,PHI:3716,UniProt,T1PTC5,GenBank,AFQ61041,,,ATCC 96836,AbPf2,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,transcription factor,,,,loss of pathogenicity,,no,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,23617599,PubMed,10.1111/tpj.12217,,yangrae@hawaii.edu,"Mutants were similar in responses to a phytoalexin, reactive oxygen species and osmolites",Y Cho 2013,2013,1 gene,Cho-2013-Fungal-specific tran,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5068,PHI:3717,UniProt,Q5SC61,GenBank,AAT95334,,,,TgMAPK1,,,,,,,5811,Toxoplasma gondii,,Prugniaud,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; brain,"mitogen-activated protein kinase (MAPK) , a virulence factor",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,23541881,PubMed,10.1016/j.exppara.2013.03.016,,michael.brumlik@sascientific.com,"Reduced parasite burdens persisted in IFN- c KO mice, but equalized in normally iNOS-replete organs from iNOS KO mice",M J Brumlik 2013,2013,1 gene,Brumlik-2013-TgMAPK1 is a Toxopla,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5069,PHI:3718,UniProt,Q4V036,GenBank,AAY47337,,,8004,XC_0250,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot (Cruciferae),eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,"encodes a protein with a class III nucleotidyl cyclase domain, is required for cyclic GMP synthesis",,,cyclic GMP and cyclic di-GMP signalling,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24056836,PubMed,10.1038/emboj.2013.165,,rpryan@dundee.ac.uk,Mutants showed reduced biofilm formation,S-Q An 2013,2013,2 genes,An-2013-A cyclic GMP-depende,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5070,PHI:3719,UniProt,Q4V037,GenBank,AAY47336,,,8004,XC_0249,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot (Cruciferae),eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,"encodes a protein with a class III nucleotidyl cyclase domain, is required for cyclic GMP synthesis",,,cyclic GMP and cyclic di-GMP signalling,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24056836,PubMed,10.1038/emboj.2013.165,,rpryan@dundee.ac.uk,Mutants showed reduced biofilm formation,S-Q An 2013,2013,2 genes,An-2013-A cyclic GMP-depende,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5071,PHI:3720,UniProt,J9WUP1,GenBank,AFS18474,,,Pd01,PdpacC,,,,,,,36651,Penicillium digitatum,1170230,Pd01,green mold,eudicots,55188,Citrus unshiu (related: satsuma mandarin),,,,exocarp,pH signaling transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; KCl,NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene disruption; gene complementation,,,RP,23917633,PubMed,10.1007/s00253-013-5129-x,,hyli@zju.edu.cn,The growth of t he deltaPdpacC mutant was severely reduced on media supplemented with NaCl and KCl and also at neutral and alkaline pH conditions.,T Zhang 2013,2013,2 genes,Zhang-2013-The pH signaling tra,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5072,PHI:3721,UniProt,J9WML2,GenBank,AFS18476,,,Pd01,Pdpg2,,,,,,,36651,Penicillium digitatum,1170230,Pd01,green mold,eudicots,55188,Citrus unshiu (related: satsuma mandarin),,,,exocarp,pH signaling transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; KCl,NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene disruption; gene complementation,,,RP,23917633,PubMed,10.1007/s00253-013-5129-x,,hyli@zju.edu.cn,PdpacC is involved in the regulation of Pdpg2,T Zhang 2013,2013,2 genes,Zhang-2013-The pH signaling tra,Batch031,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5073,PHI:3722,UniProt,Q2YN91,GenBank,CAJ10712,,,2308,BtpB,,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,effector protein,,,TLR signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23847770,PubMed,10.3389/fcimb.2013.00028,,gorvel@ciml.univ-mrs.fr,,S P Salcedo 2013,2013,1 gene,"Salcedo-2013-BtpB, a novel Brucel",Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5074,PHI:3723,UniProt,E8XEV4,GenBank,ADX16885,,,ST4/74,RNase E,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,food poisoning,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,endoribonucleases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23913419,PubMed,10.1128/AEM.02044-13,,afialho@ist.utl.pt.,,S C Viegas 2013,2013,2 genes,Viegas-2013-The virulence of Sal,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5075,PHI:3724,UniProt,Q56056,GenBank,AAA92440,,,TSM117,RNase III,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,food poisoning,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,endoribonucleases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23913419,PubMed,10.1128/AEM.02044-13,,afialho@ist.utl.pt.,,S C Viegas 2013,2013,2 genes,Viegas-2013-The virulence of Sal,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5076,PHI:3725,UniProt,P14147,GenBank,AAA27189,,,,PhoPQ,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,food poisoning,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,virulence sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23951347,PubMed,10.1371/journal.pone.0073287,,gerlachr@rki.de,,J K Bender 2013,2013,4 genes,Bender-2013-LPS Structure and Ph,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5077,PHI:3726,UniProt,P26471,GenBank,AAA27206,,,LT2,rfaL,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,food poisoning,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,O-antigen ligase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23951347,PubMed,10.1371/journal.pone.0073287,,gerlachr@rki.de,,J K Bender 2013,2013,4 genes,Bender-2013-LPS Structure and Ph,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5078,PHI:3727,UniProt,E8X960,GenBank,ADX16335,,,ST4/74,WzzfepE,,,,,,PHI:3728,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,food poisoning,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,ferric enterobactin transport protein FepE,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23951347,PubMed,10.1371/journal.pone.0073287,,gerlachr@rki.de,,J K Bender 2013,2013,4 genes,Bender-2013-LPS Structure and Ph,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5079,PHI:3728,UniProt,Q04866,GenBank,CAA78946,,,LT2,WzzST,,,,,,PHI:3727,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,food poisoning,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,chain length determinant,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23951347,PubMed,10.1371/journal.pone.0073287,,gerlachr@rki.de,,J K Bender 2013,2013,4 genes,Bender-2013-LPS Structure and Ph,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5080,PHI:3729,UniProt,E0PWJ8,GenBank,EFM33275,,,ATCC 1078,Mac/IdeS,,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,pharyngitis; impetigo; necrotizing fasciitis; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),CD-1,,,serum,IgG protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23900173,PubMed,10.1128/mBio.00499-13,,okumura@oxy.edu,,C Y M Okumura 2013,2013,1 gene,Okumura-2013-IgG protease Mac_Ide,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5081,PHI:3730,UniProt,Q6R3R4,GenBank,AAS21657,,,Bd90,BcChsVI,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,chitin synthase,,,,reduced virulence,,,,,,,,reduced,,no,sodium dodecyl sulfate (SDS); calcofluor white (CFW); congo red (CR); BCIP,sodium dodecyl sulfate (SDS): CAS:151-21-3; calcofluor white (CFW): CAS:91-44-1; Congo red: CAS:573-58-0; BCIP: CHEBI:75508,,,,,gene disruption,,,RP,23722656,PubMed,10.1007/s00294-013-0393-y,,thzhu@zjut.edu.cn,Bcchs6 mutant was sensitive to cell wall disturbing chemicals,Z Cui 2013,2013,1 gene,Cui-2013-Botrytis cinerea chi,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5082,PHI:3731,UniProt,A1AEN2,GenBank,ABJ02122,,,O1:K1,LuxS,,,,,,,562,Escherichia coli,1204723,serotype O78:K80:H9 strain χ7122,colibacillosis; cellulitis; swollen head syndrome,birds,9031,Gallus gallus (related: chicken),,,,,controller in the quorum sensing,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,23958403,PubMed,10.1016/j.vetmic.2013.07.009,,mukhopadhyays@mail.nih.gov,,S Palaniyandi 2013,2013,1 gene,Palaniyandi-2013-LuxS contributes to,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5083,PHI:3732,UniProt,B2HGU8,GenBank,ACC41651,,,M,mptC,,,,,,,1781,Mycobacterium marinum,1131442,E11,tuberculosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,mannan core branching of lipo(arabino)mannan,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,23902464,PubMed,10.1111/cmi.12175,,a.vandersar@vumc.nl,,E J M Stoop 2013,2013,1 gene,Stoop-2013-Mannan core branchin,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5084,PHI:3733,UniProt,D0ZV19,GenBank,ACY89895,,,14028S,sipA (sspA),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5085,PHI:3734,UniProt,D0ZV22,GenBank,ACY89898,,,14028S,sipB (sspB),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5086,PHI:3735,UniProt,D0ZV21,GenBank,ACY89897,,,14028S,sipC (sspC),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5087,PHI:3736,UniProt,D0ZV20,GenBank,ACY89896,,,14028S,sipD (sspD),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5088,PHI:3737,UniProt,D0ZMG9,GenBank,ACY89002,,,14028S,sopA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5089,PHI:3738,UniProt,D0ZTL7,GenBank,ACY87729,,,14028S,sopB (sigD),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5090,PHI:3739,UniProt,D0ZVN8,GenBank,ACY89963,,,14028S,sopD,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5091,PHI:3740,UniProt,D0ZK57,GenBank,ACY88707,,,14028S,sopE2,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5092,PHI:3741,UniProt,D0ZV00,GenBank,ACY89876,,,14028S,avrA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5093,PHI:3742,UniProt,D0ZTH8,GenBank,ACY87690,,,14028S,gtgE,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5094,PHI:3743,UniProt,D0ZRB2,GenBank,ACY87425,,,14028S,slrP,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5095,PHI:3744,UniProt,D0ZHS8,GenBank,ACY86471,,,14028S,spvC,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5096,PHI:3745,UniProt,D0ZHS7,GenBank,ACY86470,,,14028S,spvD,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5097,PHI:3746,UniProt,D0ZV15,GenBank,ACY89891,,,14028S,sptP,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5098,PHI:3747,UniProt,D0ZQW0,GenBank,ACY91342,,,14028S,sseK1,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5099,PHI:3748,UniProt,D0ZVG2,GenBank,AAD40326,,,14028S,sspH1,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5100,PHI:3749,UniProt,D0ZXR5,GenBank,ACY88383,,,14028S,steA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5101,PHI:3750,UniProt,D0ZI38,GenBank,ACY88441,,,14028S,steB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5102,PHI:3751,UniProt,D0ZLQ3,GenBank,ACY90915,,,14028S,cigR,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,anti virulence factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,"CigR, a recently discovered effector that is widely conserved throughout enteric bacteria. Deletion of cigR increased lethality, suggesting that it may be an anti-virulence factor",A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5103,PHI:3752,UniProt,D0ZSS1,GenBank,ACY89595,,,14028S,gogB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5104,PHI:3753,UniProt,D0ZTE8,GenBank,ACY87660,,,14028S,gtgA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5105,PHI:3754,UniProt,D0ZTL3,GenBank,ACY87725,,,14028S,pipB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5106,PHI:3755,UniProt,D0ZTZ7,GenBank,ACY89769,,,14028S,pipB2,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5107,PHI:3756,UniProt,D0ZV82,GenBank,ACY87887,,,14028S,sifA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5108,PHI:3757,UniProt,D0ZI08,GenBank,ACY88411,,,14028S,sifB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5109,PHI:3758,UniProt,D0ZSH4,GenBank,ACY87592,,,14028S,sopD2,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5110,PHI:3759,UniProt,D0ZWR8,GenBank,AAC44300,,,14028S,spiC (ssaB),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5111,PHI:3760,UniProt,D0ZHS9,GenBank,ACY86472,,,14028S,spvB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5112,PHI:3761,UniProt,D0ZRW0,GenBank,ACY89541,,,14028S,sseB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5113,PHI:3762,UniProt,D0ZWS6,GenBank,ACY88174,,,14028S,sseC,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5114,PHI:3763,UniProt,D0ZWS7,GenBank,ACY88175,,,14028S,sseD,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5115,PHI:3764,UniProt,D0ZWT0,GenBank,ACY88178,,,14028S,sseF,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5116,PHI:3765,UniProt,D0ZWT1,GenBank,ACY88179,,,14028S,sseG,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5117,PHI:3766,UniProt,D0ZTH5,GenBank,ACY87687,,,14028S,srfH (sse I/gtgB),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5118,PHI:3767,UniProt,D0ZI42,GenBank,ACY88445,,,14028S,sseJ,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5119,PHI:3768,UniProt,E1WH69,GenBank,CBW18209,,,14028S,sseK2,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5120,PHI:3769,UniProt,E1WGN6,GenBank,CBW1802,,,14028S,sseK3,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5121,PHI:3770,UniProt,D0ZPN3,GenBank,ACY89264,,,14028S,sseL,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5122,PHI:3771,UniProt,D0ZPH9,GenBank,AAF00615,,,14028S,sspH2,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5123,PHI:3772,UniProt,D0ZIB5,GenBank,ACY88518,,,14028S,steC,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5124,PHI:3773,UniProt,D0ZNF0,GenBank,ACY89081,,,14028S,steD,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5125,PHI:3774,UniProt,D0ZSS3,GenBank,ACY89597,,,14028S,pagJ,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5126,PHI:3775,UniProt,D0ZK74,GenBank,ACY8872,,,14028S,pagK1,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5127,PHI:3776,UniProt,D0ZSS4,GenBank,ACY89598,,,14028S,pagK2,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5128,PHI:3777,UniProt,D0ZVH8,GenBank,ACY87983,,,14028S,pagC,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5129,PHI:3778,UniProt,D0ZVH5,GenBank,ACY87980,,,14028S,pagD,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5130,PHI:3779,UniProt,D0ZM29,GenBank,ACY86941,,,14028S,sssA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5131,PHI:3780,UniProt,D0ZX10,GenBank,ACY88258,,,14028S,sssB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,self-limiting gastroenteritis; typhoid-like disease (mice),rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,liver; spleen,secreted effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23950998,PubMed,10.1371/journal.pone.0070753,,heffronf@ohsu.edu,,A S Kidwai 2013,2013,48 genes,Kidwai-2013-Diverse secreted eff,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5132,PHI:3781,UniProt,D0ZEM2,GenBank,ACY85867,,,EIB202,inv,,,,,,,636,Edwardsiella tarda,,H1,,bony fishes,7955,Danio rerio (related: zebrafish),,,,,required to initiate the internalization of a bacterium into the host organism,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,23600645,PubMed,10.1111/jam.12198,,xhzhang@ouc.edu. cn,,X Dong 2013,2013,1 gene,Dong-2013-Invasin of Edwardsie,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5133,PHI:3782,UniProt,Q9ZI86,GenBank,AAC97167,,,,PA3984,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,acyltransferases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23848169,PubMed,10.1111/gtc.12076,,joonhee@pusan.ac.kr,,D H Yeom 2013,2013,7 genes,Yeom-2013-Pleiotropic effects,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5134,PHI:3783,UniProt,Q9I0U7,GenBank,AE004681_7,,,PAO1,PA2537,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,acyltransferases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23848169,PubMed,10.1111/gtc.12076,,joonhee@pusan.ac.kr,,D H Yeom 2013,2013,7 genes,Yeom-2013-Pleiotropic effects,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5135,PHI:3784,UniProt,Q9HXY6,GenBank,AE004784_7,,,PAO1,PA3646,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,acyltransferases,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23848169,PubMed,10.1111/gtc.12076,,joonhee@pusan.ac.kr,,D H Yeom 2013,2013,7 genes,Yeom-2013-Pleiotropic effects,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5136,PHI:3785,UniProt,Q9X6P4,GenBank,AF142597_1,,,PAO1,PA3644,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,acyltransferases,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23848169,PubMed,10.1111/gtc.12076,,joonhee@pusan.ac.kr,,D H Yeom 2013,2013,7 genes,Yeom-2013-Pleiotropic effects,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5137,PHI:3786,UniProt,Q9I7C1,GenBank,AE004440_5,,,PAO1,PA0005,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,acyltransferases,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23848169,PubMed,10.1111/gtc.12076,,joonhee@pusan.ac.kr,,D H Yeom 2013,2013,7 genes,Yeom-2013-Pleiotropic effects,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5138,PHI:3787,UniProt,Q9HYZ8,GenBank,AE004747_3,,,PAO1,PA3242,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,acyltransferases,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23848169,PubMed,10.1111/gtc.12076,,joonhee@pusan.ac.kr,,D H Yeom 2013,2013,7 genes,Yeom-2013-Pleiotropic effects,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5139,PHI:3788,UniProt,Q9HW50,GenBank,AE004747_3,,,PAO1,PA4351,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,acyltransferases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23848169,PubMed,10.1111/gtc.12076,,joonhee@pusan.ac.kr,,D H Yeom 2013,2013,7 genes,Yeom-2013-Pleiotropic effects,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5140,PHI:3789,UniProt,A1AJK4,GenBank,ABJ03844,,,APEC O1,ibeA,,,,,,,562,Escherichia coli,1204723,serotype O78:H9,colibacillosis; cellulitis; swollen head syndrome,birds,9031,Gallus gallus (related: chicken),Cobb,,,liver,invasins,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,functional test in host,,,RP,23977279,PubMed,10.1371/journal.pone.0072322,,fabiana.horn@ufrg s.br,,N L Barbieri 2013,2013,4 genes,Barbieri-2013-Genotypes and Pathog,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5141,PHI:3790,,no data found,,,,,,gimB,,,,,,,562,Escherichia coli,1204723,serotype O78:H9,colibacillosis; cellulitis; swollen head syndrome,birds,9031,Gallus gallus (related: chicken),Cobb,,,liver,invasins,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,functional test in host,,,RP,23977279,PubMed,10.1371/journal.pone.0072322,,fabiana.horn@ufrg s.br,,N L Barbieri 2013,2013,4 genes,Barbieri-2013-Genotypes and Pathog,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5142,PHI:3791,,no data found,,,,,,KpsMTII,,,,,,,562,Escherichia coli,1204723,serotype O78:H9,colibacillosis; cellulitis; swollen head syndrome,birds,9031,Gallus gallus (related: chicken),Cobb,,,liver,group II capsule,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,functional test in host,,,RP,23977279,PubMed,10.1371/journal.pone.0072322,,fabiana.horn@ufrg s.br,,N L Barbieri 2013,2013,4 genes,Barbieri-2013-Genotypes and Pathog,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5143,PHI:3792,UniProt,Q7BS42,GenBank,AAD23953,,,42,pic,,,,,,,562,Escherichia coli,1204723,serotype O78:H9,colibacillosis; cellulitis; swollen head syndrome,birds,9031,Gallus gallus (related: chicken),Cobb,,,liver,serin protease aut o transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,functional test in host,,,RP,23977279,PubMed,10.1371/journal.pone.0072322,,fabiana.horn@ufrg s.br,,N L Barbieri 2013,2013,4 genes,Barbieri-2013-Genotypes and Pathog,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5144,PHI:3793,UniProt,Q6FM27,GenBank,CAG61680,,,CBS 138,ANP1,,,,,,,5478,Candida glabrata,,CBS 138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,encode alpha-(1-6)-mannosyl-transferases,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,23720756,PubMed,10.1074/jbc.M113.478743,,k.haynes@exeter.ac.uk,,L West 2013,2013,3 genes,West-2013-Differential Virulen,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5145,PHI:3794,UniProt,Q6FQP8,GenBank,CAG60383,,,CBS 138,MNN2,,,,,,,5478,Candida glabrata,,CBS 138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,encodes alpha-(1-2)-mannosyltransferase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,23720756,PubMed,10.1074/jbc.M113.478743,,k.haynes@exeter.ac.uk,,L West 2013,2013,3 genes,West-2013-Differential Virulen,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5146,PHI:3795,UniProt,Q6FSV7,GenBank,CAG59614,,,CBS 138,MNN11,,,,,,,5478,Candida glabrata,,CBS 138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,encode alpha-(1-6)-mannosyl-transferases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,23720756,PubMed,10.1074/jbc.M113.478743,,k.haynes@exeter.ac.uk,,L West 2013,2013,3 genes,West-2013-Differential Virulen,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5147,PHI:3796,UniProt,Q881J7,GenBank,AAO56389,,,DC3000,Pst-Lov,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,regulates light affected growth,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene deletion; gene complementation,,,RP,23865633,PubMed,10.1111/tpj.12289,,casal@ifeva.edu.ar,,V Moriconi 2013,2013,1 gene,Moriconi-2013-LOV-domain photorece,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5148,PHI:3797,UniProt,S4UKV2,GenBank,KC466081,,,Bv5-4a,Fha1,,,,,,,339,Xanthomonas campestris,456327,pv. vesicatoria strain Bv5-4a,,eudicots,4072,Capsicum annuum (no common name found),cv. Nockwang,,,leaf,small filamentous hemagglutinin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23931712,PubMed,10.1094/MPMI-07-13-0204-R,,bkhwang@korea.ac.kr,,H W Choi 2013,2013,1 gene,Choi-2013-Xanthomonas Filament,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5149,PHI:3797,UniProt,S4UKV2,GenBank,KC466081,,,Bv5-4a,Fha1,,,,,,,339,Xanthomonas campestris,456327,pv. vesicatoria strain Bv5-4a,,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Kwang-Bok,,,leaf,small filamentous hemagglutinin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23931712,PubMed,10.1094/MPMI-07-13-0204-R,,bkhwang@korea.ac.kr,,H W Choi 2013,2013,1 gene,Choi-2013-Xanthomonas Filament,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5150,PHI:3798,UniProt,Q59U10,GenBank,EAK93964,,,SC5314,bcr1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,biofilm formation,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion,,,RP,23962311,PubMed,10.1111/cmi.12184,,uwe.himmelreich@med.kuleuven.be,here extending the reduction in biofilm formation to reduced pathogenicity,G V Velde 2013,2013,1 gene,Vande Velde-2013-Towards non-invasive,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5151,PHI:3799,UniProt,Q4UQG3,GenBank,AAY50710,,,8004,hpaR2,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,encodes a putative TCS response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,23906314,PubMed,10.1111/1462-2920.12207,,jltang@gxu.edu.cn,,R Li 2013,2013,2 genes,Li-2013-Identification of a,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5152,PHI:3800,UniProt,Q4UQG2,GenBank,AAY50711,,,8004,hpaS,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,TCS sensor kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,23906314,PubMed,10.1111/1462-2920.12207,,jltang@gxu.edu.cn,,R Li 2013,2013,2 genes,Li-2013-Identification of a,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5153,PHI:3801,UniProt,J9VQQ3,GenBank,AFR94914,,,H99,Pmc1,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,putative vacuolar calcium ATPase,,,ca2+-calcineurin signaling pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,23895559,PubMed,10.1111/febs.12458,,mhv@cbiot.ufr gs.br,Growth reduced under high calcium conditions,L Kmetzsch 2013,2013,2 genes,Kmetzsch-2013-The calcium transpor,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5154,PHI:3802,UniProt,J9VDQ4,GenBank,AFR92163,,,H99,Vcx1,,,,,,PHI:3801,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,calcium transporters,,,ca2+-calcineurin signaling pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,23895559,PubMed,10.1111/febs.12458,,mhv@cbiot.ufr gs.br,Growth reduced under high calcium conditions,L Kmetzsch 2013,2013,2 genes,Kmetzsch-2013-The calcium transpor,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5155,PHI:3801,UniProt,J9VQQ3,GenBank,AFR94914,,,H99,Pmc1,,,,,,PHI:3802,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,putative vacuolar calcium ATPase,,,ca2+-calcineurin signaling pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,23895559,PubMed,10.1111/febs.12458,,mhv@cbiot.ufr gs.br,Growth reduced under high calcium conditions,L Kmetzsch 2013,2013,2 genes,Kmetzsch-2013-The calcium transpor,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5156,PHI:3803,UniProt,P43459,GenBank,CAA88445,,,E2348/69,PerA,,,,,,,562,Escherichia coli,83334,serotype O157:H7 strain EDL933,hemorrhagic colitis; hemolytic uremic syndrome,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,LPS O-side chain,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,23747730,PubMed,10.1016/j.bbrc.2013.05.111,,jwy706@gmail.com,,M Youn 2013,2013,1 gene,Youn-2013-Escherichia coli O15,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5157,PHI:3804,,no data found,GenBank,NC_013316,,,R20291,AgrA,,,,,,,1496,Clostridioides difficile,645463,R20291,,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,23772065,PubMed,10.1128/JB.00473-13,,wren@lshtm.ac.uk.,Pathogen formerly called Clostridium difficile,M J Martin 2013,2013,1 gene,Martin-2013-The agr Locus Regula,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5158,PHI:3805,UniProt,Q5AJU7,GenBank,EAL02912,,,SC5314,Cap1,,,,,,,5476,Candida albicans,,JC747,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,AP-1-like transcription factor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion,,,RP,23706023,PubMed,10.1089/ars.2013.5199,,janet.quinn@ncl.ac.uk,,M J Patterson 2013,2013,3 genes,Patterson-2013-Ybp1 and Gpx3 Signal,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5159,PHI:3806,UniProt,Q5AKU3,GenBank,EAL03471,,,SC5314,Ybp1,,,,,,,5476,Candida albicans,,JC747,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,functions to stabilise Cap1,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion,,,RP,23706023,PubMed,10.1089/ars.2013.5199,,janet.quinn@ncl.ac.uk,,M J Patterson 2013,2013,3 genes,Patterson-2013-Ybp1 and Gpx3 Signal,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5160,PHI:3807,UniProt,Q59WD3,GenBank,EAK94781,,,SC5314,Gpx3,,,,,,,5476,Candida albicans,,JC747,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,glutathione peroxidase-like enzyme,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion,,,RP,23706023,PubMed,10.1089/ars.2013.5199,,janet.quinn@ncl.ac.uk,,M J Patterson 2013,2013,3 genes,Patterson-2013-Ybp1 and Gpx3 Signal,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5161,PHI:3808,UniProt,I1S0C0,GenBank,XM_390318,,,PH-1,Atf1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,ATF/CREB transcription factor,,,,reduced virulence,,,,,,,reduced,,aberrant,no,D-sorbitol; NaCl; KCl; H2O2; fludioxonil,NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,RP,23945004,PubMed,10.1094/MPMI-04-13-0125-R,,bormannj@botanik.uni5hamburg.de,Deletion mutants in Fgatf1 (deltaFgatf1) are more sensitive to osmotic stress and less sensitive to oxidative stress compared to the wild type,T V Nguyen 2013,2013,1 gene,Nguyen-2013-The ATF_CREB transcr,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5162,PHI:3808,UniProt,I1S0C0,GenBank,XM_390318,,,PH-1,Atf1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Amaretto,,,spikelet,ATF/CREB transcription factor,,,,reduced virulence,,,,,,,reduced,,aberrant,no,D-sorbitol; NaCl; KCl; H2O2; fludioxonil,NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,RP,23945004,PubMed,10.1094/MPMI-04-13-0125-R,,bormannj@botanik.uni5hamburg.de,Deletion mutants in Fgatf1 (deltaFgatf1) are more sensitive to osmotic stress and less sensitive to oxidative stress compared to the wild type,T V Nguyen 2013,2013,1 gene,Nguyen-2013-The ATF_CREB transcr,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5163,PHI:3808,UniProt,I1S0C0,GenBank,XM_390318,,,PH-1,Atf1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. A188,,,spikelet,ATF/CREB transcription factor,,,,reduced virulence,,,,,,,reduced,,aberrant,no,D-sorbitol; NaCl; KCl; H2O2; fludioxonil,NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,RP,23945004,PubMed,10.1094/MPMI-04-13-0125-R,,bormannj@botanik.uni5hamburg.de,Deletion mutants in Fgatf1 (deltaFgatf1) are more sensitive to osmotic stress and less sensitive to oxidative stress compared to the wild type,T V Nguyen 2013,2013,1 gene,Nguyen-2013-The ATF_CREB transcr,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5164,PHI:3808,UniProt,I1S0C0,GenBank,XM_390318,,,PH-1,Atf1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),cv. Bd21,,,spikelet,ATF/CREB transcription factor,,,,reduced virulence,,,,,,,reduced,,aberrant,no,D-sorbitol; NaCl; KCl; H2O2; fludioxonil,NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,RP,23945004,PubMed,10.1094/MPMI-04-13-0125-R,,bormannj@botanik.uni5hamburg.de,Deletion mutants in Fgatf1 (deltaFgatf1) are more sensitive to osmotic stress and less sensitive to oxidative stress compared to the wild type,T V Nguyen 2013,2013,1 gene,Nguyen-2013-The ATF_CREB transcr,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5165,PHI:3808,UniProt,I1S0C0,GenBank,XM_390318,,,PH-1,Atf1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,ATF/CREB transcription factor,,,,increased virulence (hypervirulence),,,,,,,wild type,,wild type,no,D-sorbitol; NaCl; KCl; H2O2; fludioxonil,NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,RP,23945004,PubMed,10.1094/MPMI-04-13-0125-R,,bormannj@botanik.uni5hamburg.de,,T V Nguyen 2013,2013,1 gene,Nguyen-2013-The ATF_CREB transcr,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5166,PHI:3808,UniProt,I1S0C0,GenBank,XM_390318,,,PH-1,Atf1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Amaretto,,,spikelet,ATF/CREB transcription factor,,,,increased virulence (hypervirulence),,,,,,,wild type,,wild type,no,D-sorbitol; NaCl; KCl; H2O2; fludioxonil,NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,RP,23945004,PubMed,10.1094/MPMI-04-13-0125-R,,bormannj@botanik.uni5hamburg.de,,T V Nguyen 2013,2013,1 gene,Nguyen-2013-The ATF_CREB transcr,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5167,PHI:3808,UniProt,I1S0C0,GenBank,XM_390318,,,PH-1,Atf1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. A188,,,spikelet,ATF/CREB transcription factor,,,,increased virulence (hypervirulence),,,,,,,wild type,,wild type,no,D-sorbitol; NaCl; KCl; H2O2; fludioxonil,NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,RP,23945004,PubMed,10.1094/MPMI-04-13-0125-R,,bormannj@botanik.uni5hamburg.de,,T V Nguyen 2013,2013,1 gene,Nguyen-2013-The ATF_CREB transcr,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5168,PHI:3808,UniProt,I1S0C0,GenBank,XM_390318,,,PH-1,Atf1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),cv. Bd21,,,spikelet,ATF/CREB transcription factor,,,,increased virulence (hypervirulence),,,,,,,wild type,,wild type,no,D-sorbitol; NaCl; KCl; H2O2; fludioxonil,NaCl: CHEBI:26710; KCl: CHEBI:32588; glucose: CHEBI:17234; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,RP,23945004,PubMed,10.1094/MPMI-04-13-0125-R,,bormannj@botanik.uni5hamburg.de,,T V Nguyen 2013,2013,1 gene,Nguyen-2013-The ATF_CREB transcr,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5169,PHI:3809,UniProt,G4N1E0,GenBank,EHA52411,,,70-15,TRA1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,transcription factor,,,,reduced virulence,,yes,,,,,,,reduced,no,,,,,,,gene deletion; gene complementation,,,RP,23733043,PubMed,10.1016/j.fgb.2013.05.008,,foster@ibwf.de,,B Breth 2013,2013,4 genes,Breth-2013-The role of the Tra1,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5170,PHI:3809,UniProt,G4N1E0,GenBank,EHA52411,,,70-15,TRA1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,transcription factor,,,,reduced virulence,,yes,,,,,,,reduced,no,,,,,,,gene deletion; gene complementation,,,RP,23733043,PubMed,10.1016/j.fgb.2013.05.008,,foster@ibwf.de,,B Breth 2013,2013,4 genes,Breth-2013-The role of the Tra1,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5171,PHI:3810,UniProt,G4NBR8,GenBank,EHA48976,,,70-15,TDG2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,transcription factor,,,,reduced virulence,,,,,,,,,reduced,no,,,,,,,gene deletion,,,RP,23733043,PubMed,10.1016/j.fgb.2013.05.008,,foster@ibwf.de,,B Breth 2013,2013,4 genes,Breth-2013-The role of the Tra1,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5172,PHI:3810,UniProt,G4NBR8,GenBank,EHA48976,,,70-15,TDG2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,transcription factor,,,,reduced virulence,,,,,,,,,reduced,no,,,,,,,gene deletion,,,RP,23733043,PubMed,10.1016/j.fgb.2013.05.008,,foster@ibwf.de,,B Breth 2013,2013,4 genes,Breth-2013-The role of the Tra1,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5173,PHI:3811,UniProt,G4NAT7,GenBank,EHA50529,,,70-15,TDG4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,,,,,reduced virulence,,,,,,,,,reduced,no,,,,,,,gene deletion,,,RP,23733043,PubMed,10.1016/j.fgb.2013.05.008,,foster@ibwf.de,,B Breth 2013,2013,4 genes,Breth-2013-The role of the Tra1,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5174,PHI:3811,UniProt,G4NAT7,GenBank,EHA50529,,,70-15,TDG4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,,,,,reduced virulence,,,,,,,,,reduced,no,,,,,,,gene deletion,,,RP,23733043,PubMed,10.1016/j.fgb.2013.05.008,,foster@ibwf.de,,B Breth 2013,2013,4 genes,Breth-2013-The role of the Tra1,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5175,PHI:3812,,no data found,GenBank,XP_365986,,,70-15,TDG6,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,encodes a predicted extracellular protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,RP,23733043,PubMed,10.1016/j.fgb.2013.05.008,,foster@ibwf.de,,B Breth 2013,2013,4 genes,Breth-2013-The role of the Tra1,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5176,PHI:3812,,no data found,GenBank,XP_365986,,,70-15,TDG6,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,encodes a predicted extracellular protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,RP,23733043,PubMed,10.1016/j.fgb.2013.05.008,,foster@ibwf.de,,B Breth 2013,2013,4 genes,Breth-2013-The role of the Tra1,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5177,PHI:3813,UniProt,Q30MW3,GenBank,AAY58372,,,B1,gp43,,,,,,,121759,Paracoccidioides brasiliensis,,Pb339,paracoccidioidomycosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,glycoprotein an immunodominant diagnostic antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,23874627,PubMed,10.1371/journal.pone.0068434,,isaurap10@gmail.com,antisense RNA (aRNA) technology and Agrobacterium tumefaciens -mediated transformation to generate mitotically stable Pb GP43 mutants,I Torres 2013,2013,1 gene,Torres-2013-Inhibition of PbGP43,Batch031b,2013-10-01,MC,,,,,,,,,,,,,
,,Record 5178,PHI:3814,UniProt,G4NES1,GenBank,EHA49494,,,70-15,AGL1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,glycogen debranching enzymye,,,cAMP response pathway,reduced virulence,,no,,yes,,wild type,,,,no,,,,,,,gene disruption,,,RP,24098112,PubMed,10.1371/journal.ppat.1003604,,N.J.Tal bot@exeter .ac.uk,,M Badaruddin 2013,2013,3 genes,Badaruddin-2013-Glycogen Metabolic G,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5179,PHI:3815,UniProt,G4MW66,GenBank,EHA55026,,,70-15,GPH1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,phosphorylase,,,cAMP response pathway,reduced virulence,,no,,yes,,wild type,,,,no,,,,,,,gene disruption,,,RP,24098112,PubMed,10.1371/journal.ppat.1003604,,N.J.Tal bot@exeter .ac.uk,,M Badaruddin 2013,2013,3 genes,Badaruddin-2013-Glycogen Metabolic G,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5180,PHI:3816,UniProt,G4MUX6,GenBank,EHA55710,,,70-15,GSN1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,glycogen synthase,,,cAMP response pathway,reduced virulence,,no,,yes,,wild type,,,,no,,,,,,,gene disruption,,,RP,24098112,PubMed,10.1371/journal.ppat.1003604,,N.J.Tal bot@exeter .ac.uk,,M Badaruddin 2013,2013,3 genes,Badaruddin-2013-Glycogen Metabolic G,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5181,PHI:3814,UniProt,G4NES1,GenBank,EHA49494,,,70-15,AGL1,,,,,,PHI:3815,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,glycogen debranching enzymye,,,cAMP response pathway,reduced virulence,,no,,yes,,wild type,,,,no,,,,,,,gene disruption,,,RP,24098112,PubMed,10.1371/journal.ppat.1003604,,N.J.Tal bot@exeter .ac.uk,,M Badaruddin 2013,2013,3 genes,Badaruddin-2013-Glycogen Metabolic G,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5182,PHI:3815,UniProt,G4MW66,GenBank,EHA55026,,,70-15,GPH1,,,,,,PHI:3814,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,phosphorylase,,,cAMP response pathway,reduced virulence,,no,,yes,,wild type,,,,no,,,,,,,gene disruption,,,RP,24098112,PubMed,10.1371/journal.ppat.1003604,,N.J.Tal bot@exeter .ac.uk,,M Badaruddin 2013,2013,3 genes,Badaruddin-2013-Glycogen Metabolic G,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5183,PHI:3814,UniProt,G4NES1,GenBank,EHA49494,,,70-15,AGL1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,glycogen debranching enzymye,,,cAMP response pathway,reduced virulence,,no,,yes,,wild type,,,,no,,,,,,,gene disruption,,,RP,24098112,PubMed,10.1371/journal.ppat.1003604,,N.J.Tal bot@exeter .ac.uk,,M Badaruddin 2013,2013,3 genes,Badaruddin-2013-Glycogen Metabolic G,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5184,PHI:3815,UniProt,G4MW66,GenBank,EHA55026,,,70-15,GPH1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,phosphorylase,,,cAMP response pathway,reduced virulence,,no,,yes,,wild type,,,,no,,,,,,,gene disruption,,,RP,24098112,PubMed,10.1371/journal.ppat.1003604,,N.J.Tal bot@exeter .ac.uk,,M Badaruddin 2013,2013,3 genes,Badaruddin-2013-Glycogen Metabolic G,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5185,PHI:3816,UniProt,G4MUX6,GenBank,EHA55710,,,70-15,GSN1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,glycogen synthase,,,cAMP response pathway,reduced virulence,,no,,yes,,wild type,,,,no,,,,,,,gene disruption,,,RP,24098112,PubMed,10.1371/journal.ppat.1003604,,N.J.Tal bot@exeter .ac.uk,,M Badaruddin 2013,2013,3 genes,Badaruddin-2013-Glycogen Metabolic G,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5186,PHI:3814,UniProt,G4NES1,GenBank,EHA49494,,,70-15,AGL1,,,,,,PHI:3815,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,glycogen debranching enzymye,,,cAMP response pathway,reduced virulence,,no,,yes,,wild type,,,,no,,,,,,,gene disruption,,,RP,24098112,PubMed,10.1371/journal.ppat.1003604,,N.J.Tal bot@exeter .ac.uk,,M Badaruddin 2013,2013,3 genes,Badaruddin-2013-Glycogen Metabolic G,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5187,PHI:3815,UniProt,G4MW66,GenBank,EHA55026,,,70-15,GPH1,,,,,,PHI:3814,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,phosphorylase,,,cAMP response pathway,reduced virulence,,no,,yes,,wild type,,,,no,,,,,,,gene disruption,,,RP,24098112,PubMed,10.1371/journal.ppat.1003604,,N.J.Tal bot@exeter .ac.uk,,M Badaruddin 2013,2013,3 genes,Badaruddin-2013-Glycogen Metabolic G,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5188,PHI:3817,UniProt,E9EQM1,GenBank,EFZ02580,,,ARSEF 23,mrGAT,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,glycerol-3-phosphate O-acyltransferase,,,cAMP response pathway,reduced virulence,,no,yes,no,,reduced,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24077712,PubMed,10.1128/AEM.02905-13,,cswang@sibs.ac.cn16,"MAA_02162- here they mention this accession for the gene in the paper and I have taken it as such, however, it belongs to the taxon Metarhizium anisopliae- kindly check",Q Gao 2013,2013,1 gene,Gao-2013-Glycerol-3-phosphate,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5189,PHI:3818,UniProt,R4NUG0,GenBank,AGL47857,,,TL13,Hhly3,,,,,,,1307,Streptococcus suis,,ZY05719,streptococcal toxic shock syndrome,bony fishes,7955,Danio rerio (related: zebrafish),,,,,encodes a putative hemolysin-III-related protein,,,,reduced virulence,,,,,,,,,,,,,,,,,gene deletion; gene complementation,,,RP,24069329,PubMed,10.1371/journal.pone.0074674,,fhj@njau.edu.cn,"hemolysin-III-related protein was not found, took Hemolysin III- not sure if it is correct",J Zheng 2013,2013,1 gene,Zheng-2013-Identification and C,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5190,PHI:3819,UniProt,P0A3X0,GenBank,CAL21733,,,CO92,ymoA,,,,,,,632,Yersinia pestis,,KIM/D27,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,represses the transcription and expression of T3SS genes at room temperature,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion,,,RP,23988036,PubMed,10.1089/ast.2013.0968,,rosenzweigja@tsu.edu,"no significant differences were observed in survival of mice infected intraperitoneally with either normal gravity (NG)- or CR-grown parental YP, the DeltaymoA mutant induced significantly more mortality in infected mice than did the parental strain following CR growth",A Lawal 2013,2013,1 gene,Lawal-2013-The Effects of Model,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5191,PHI:3820,UniProt,B2HSW7,GenBank,ACC41141,,,M,secA2,,,,,,,1781,Mycobacterium marinum,1131442,E11,granuloma,bony fishes,7955,Danio rerio (related: zebrafish),,,,,preprotein translocase ATPase,,,,reduced virulence,,,,,,,,,,no,ethambutol; meropenem,ethambutol: CHEBI:4877; meropenem: CHEBI:43968,,,,,gene deletion,,,RP,24119166,PubMed,10.1111/cmi.12221,,w.bitter@vumc.nl,"Overexpression of PknG in the secA2 mutant restored its localization to the cell envelope. Importantly, PknG-overexpression also partially restored the virulence of the secA2 mutant, as indicated by enhanced infectivity in zebrafish embryos and restored inhibition of phagosomal maturation",A D van der Woude 2013,2013,1 gene,van der Woude-2013-Analysis of SecA2-de,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5192,PHI:3821,UniProt,Q58PK3,GenBank,AAX47094,,,,SconCp,,,,,,,121759,Paracoccidioides brasiliensis,,ATCC 60855,paracoccidioidomycosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,negative regulator of the inorganic sulfur assimilation pathway,,,inorganic sulfur assimilation pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,altered gene expression / gene regulation,,,RP,24066151,PubMed,10.1371/journal.pone.0074725,,frodrigues@ecsaude.uminho.pt,,J F Menino 2013,2013,1 gene,Menino-2013-P. brasiliensis Viru,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5193,PHI:3822,UniProt,Q5A1L6,GenBank,EAK96669,,,SC5314,GIT3,chromosome 5,,,,,,5476,Candida albicans,,DAY185,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,groPCho permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24114876,PubMed,10.1074/jbc.M113.505735,,pattonvogt@duq.edu,,A C Bishop 2013,2013,1 gene,Bishop-2013-Glycerophosphocholin,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5194,PHI:3823,UniProt,G4MV96,GenBank,EHA54918,,,70-15,MET13,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,methylenetetrahydrofolate reductase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,methionine,methionine: CHEBI:16811,,,,,gene deletion; gene complementation,,,RP,24116181,PubMed,10.1371/journal.pone.0076914,,zhywang@zju.edu.cn,All phenotypes associated with deltamet13 mutants could be overcome by addition of exogenous methionine,X Yan 2013,2013,2 genes,Yan-2013-The Methylenetetrahy,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5195,PHI:3824,UniProt,G4MZ63,GenBank,EHA55336,,,70-15,MET12,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,methylenetetrahydrofolate reductase,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,methionine,methionine: CHEBI:16811,,,,,gene deletion; gene complementation,,,RP,24116181,PubMed,10.1371/journal.pone.0076914,,zhywang@zju.edu.cn,All phenotypes associated with deltamet13 mutants could be overcome by addition of exogenous methionine,X Yan 2013,2013,2 genes,Yan-2013-The Methylenetetrahy,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5196,PHI:3823,UniProt,G4MV96,GenBank,EHA54918,,,70-15,MET13,,,,,,PHI:3824,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,methylenetetrahydrofolate reductase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,methionine,methionine: CHEBI:16811,,,,,gene deletion; gene complementation,,,RP,24116181,PubMed,10.1371/journal.pone.0076914,,zhywang@zju.edu.cn,All phenotypes associated with deltamet13 mutants could be overcome by addition of exogenous methionine,X Yan 2013,2013,2 genes,Yan-2013-The Methylenetetrahy,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5197,PHI:3824,UniProt,G4MZ63,GenBank,EHA55336,,,70-15,MET12,,,,,,PHI:3823,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,methylenetetrahydrofolate reductase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,methionine,methionine: CHEBI:16811,,,,,gene deletion; gene complementation,,,RP,24116181,PubMed,10.1371/journal.pone.0076914,,zhywang@zju.edu.cn,All phenotypes associated with deltamet13 mutants could be overcome by addition of exogenous methionine,X Yan 2013,2013,2 genes,Yan-2013-The Methylenetetrahy,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5198,PHI:3823,UniProt,G4MV96,GenBank,EHA54918,,,70-15,MET13,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,methylenetetrahydrofolate reductase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,methionine,methionine: CHEBI:16811,,,,,gene deletion; gene complementation,,,RP,24116181,PubMed,10.1371/journal.pone.0076914,,zhywang@zju.edu.cn,All phenotypes associated with deltamet13 mutants could be overcome by addition of exogenous methionine,X Yan 2013,2013,2 genes,Yan-2013-The Methylenetetrahy,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5199,PHI:3824,UniProt,G4MZ63,GenBank,EHA55336,,,70-15,MET12,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,methylenetetrahydrofolate reductase,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,methionine,methionine: CHEBI:16811,,,,,gene deletion; gene complementation,,,RP,24116181,PubMed,10.1371/journal.pone.0076914,,zhywang@zju.edu.cn,All phenotypes associated with deltamet13 mutants could be overcome by addition of exogenous methionine,X Yan 2013,2013,2 genes,Yan-2013-The Methylenetetrahy,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5200,PHI:3823,UniProt,G4MV96,GenBank,EHA54918,,,70-15,MET13,,,,,,PHI:3824,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,methylenetetrahydrofolate reductase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,methionine,methionine: CHEBI:16811,,,,,gene deletion; gene complementation,,,RP,24116181,PubMed,10.1371/journal.pone.0076914,,zhywang@zju.edu.cn,All phenotypes associated with deltamet13 mutants could be overcome by addition of exogenous methionine,X Yan 2013,2013,2 genes,Yan-2013-The Methylenetetrahy,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5201,PHI:3824,UniProt,G4MZ63,GenBank,EHA55336,,,70-15,MET12,,,,,,PHI:3823,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,methylenetetrahydrofolate reductase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,methionine,methionine: CHEBI:16811,,,,,gene deletion; gene complementation,,,RP,24116181,PubMed,10.1371/journal.pone.0076914,,zhywang@zju.edu.cn,All phenotypes associated with deltamet13 mutants could be overcome by addition of exogenous methionine,X Yan 2013,2013,2 genes,Yan-2013-The Methylenetetrahy,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5202,PHI:3825,UniProt,J9VFB0,GenBank,AFR92783,,,H99,Srx1,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,lung,required for cells to counteract peroxide stress,,,HOG signalling pathway,reduced virulence,no,,,,,,wild type,wild type,,no,diamide; menadione; tert -butyl hydroperoxide (tBOOH); paraquat; H2O2 ;amphotericin B; fluconazole; itraconazole; ketoconazole,"menadione: CHEBI:28869; tert -butyl hydroperoxide (tBOOH): CHEBI:64090; paraquat: CHEBI:34905; H2O2: CHEBI:16240; amphotericin B: CHEBI:277842; itraconazole: CHEBI:6076; ketoconazole: CHEBI:47519, CAS:65277-42-1",,,,,gene disruption; gene complementation,,,RP,23998805,PubMed,10.1111/mmi.12388,,lodgej@wusm.wustl.edu,The C. neoformans HOG pathway was essential for the transcriptional regulation of SRX1 under peroxide stress conditions.,R Upadhya 2013,2013,1 gene,Upadhya-2013-Sulphiredoxin plays,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5203,PHI:3825,UniProt,J9VFB0,GenBank,AFR92783,,,H99,Srx1,,,,,,,5207,Cryptococcus neoformans,,KN99α,,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,lung,required for cells to counteract peroxide stress,,,HOG signalling pathway,reduced virulence,no,,,,,,wild type,wild type,,no,diamide; menadione; tert -butyl hydroperoxide (tBOOH); paraquat; H2O2 ;amphotericin B; fluconazole; itraconazole; ketoconazole,"menadione: CHEBI:28869; tert -butyl hydroperoxide (tBOOH): CHEBI:64090; paraquat: CHEBI:34905; H2O2: CHEBI:16240; amphotericin B: CHEBI:277842; itraconazole: CHEBI:6076; ketoconazole: CHEBI:47519, CAS:65277-42-1",,,,,gene disruption; gene complementation,,,RP,23998805,PubMed,10.1111/mmi.12388,,lodgej@wusm.wustl.edu,The C. neoformans HOG pathway was essential for the transcriptional regulation of SRX1 under peroxide stress conditions.,R Upadhya 2013,2013,1 gene,Upadhya-2013-Sulphiredoxin plays,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5204,PHI:3826,UniProt,P05431,GenBank,CAA30557,,,C311,PilE,,,,,,,487,Neisseria meningitidis,122586,MC58,,rodents,10090,Mus musculus (related: house mouse),CD46 transgenic,,,brain,"the ligands for TNF-a and IL-8 in a glycan-dependent manner, and their del-etion results in decreased virulence and increased survival in a mouse model",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,RP,24107297,PubMed,10.1098/rsob.130048,,jafar.mahdavi@nottingham.ac.uk,,J Mahdavi 2013,2013,2 genes,Mahdavi-2013-Pro-inflammatory cyt,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5205,PHI:3827,UniProt,Q70M91,GenBank,PILQ_NEIMB,,,MC58,PilQ,,,,,,,487,Neisseria meningitidis,122586,MC58,,rodents,10090,Mus musculus (related: house mouse),CD46 transgenic,,,brain,"the ligands for TNF-a and IL-8 in a glycan-dependent manner, and their del-etion results in decreased virulence and increased survival in a mouse model",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,RP,24107297,PubMed,10.1098/rsob.130048,,jafar.mahdavi@nottingham.ac.uk,,J Mahdavi 2013,2013,2 genes,Mahdavi-2013-Pro-inflammatory cyt,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5206,PHI:3828,UniProt,S5FRT9,GenBank,AGQ43489,,,PH-1,AbaA,,,,,,,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,involved in differentiation from vegetative hyphae to conidia,,,AbaA-WetA pathway,unaffected pathogenicity,no,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion; gene complementation,,,RP,24039821,PubMed,10.1371/journal.pone.0072915,,lee2443@snu.ac.kr,,H Son 2013,2013,1 gene,Son-2013-AbaA Regulates Conid,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5207,PHI:3829,UniProt,Q2YS16,GenBank,CAJ11448,,,2308,SepA,,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,type IV secretion substrate,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24119283,PubMed,10.1111/cmi.12224,,jugalde@iibintech.com.ar,,P H Dohmer 2013,2013,1 gene,Dohmer-2013-Identification of a,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5208,PHI:3829,UniProt,Q2YS16,GenBank,CAJ11448,,,2308,SepA,,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,type IV secretion substrate,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,24119283,PubMed,10.1111/cmi.12224,,jugalde@iibintech.com.ar,,P H Dohmer 2013,2013,1 gene,Dohmer-2013-Identification of a,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5209,PHI:3830,,no data found,,,,,,sX13,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,represents a novel class of virulence regulators and provides insights into sRNA-mediated modulation of adaptive processes in the plant pathogen Xanthomonas .,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24068933,PubMed,10.1371/journal.ppat.1003626,,cornelius.schubert@genetik.unihalle.de,"Small noncoding RNAs (sRNAs), therefore accession numbers not found",C Schmidtke 2013,2013,1 gene,Schmidtke-2013-Small RNA sX13_ A Mu,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5210,PHI:3830,,no data found,,,,,,sX13,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,represents a novel class of virulence regulators and provides insights into sRNA-mediated modulation of adaptive processes in the plant pathogen Xanthomonas .,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24068933,PubMed,10.1371/journal.ppat.1003626,,cornelius.schubert@genetik.unihalle.de,"Small noncoding RNAs (sRNAs), therefore accession numbers not found",C Schmidtke 2013,2013,1 gene,Schmidtke-2013-Small RNA sX13_ A Mu,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5211,PHI:3831,UniProt,V6RR76,FGDB,FGSG_08857,,,,Fgrac1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bainong 979,,,spikelet,Rho GTPases,,,,reduced virulence,yes,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24055721,PubMed,10.1016/j.fgb.2013.09.001,,wbshim@neo.tamu.edu,,C Zhang 2013,2013,6 genes,Zhang-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5212,PHI:3832,UniProt,I1RN81,FGDB,FGSG_05447,,,,Fgcdc42,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bainong 979,,,spikelet,Rho GTPases,,,,reduced virulence,yes,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24055721,PubMed,10.1016/j.fgb.2013.09.001,,wbshim@neo.tamu.edu,,C Zhang 2013,2013,6 genes,Zhang-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5213,PHI:3833,UniProt,A0A098DKM1,EMBL,FGRAMPH1_01T14389,,,,Fgrho2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bainong 979,,,spikelet,Rho GTPases,,,,reduced virulence,yes,,,,,,reduced,,,no,,,,,,,gene deletion; gene complementation,,,RP,24055721,PubMed,10.1016/j.fgb.2013.09.001,,wbshim@neo.tamu.edu,,C Zhang 2013,2013,6 genes,Zhang-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5214,PHI:3834,UniProt,I1R9M1,FGDB,FGSG_00170,,,,Fgrho3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bainong 979,,,spikelet,Rho GTPases,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24055721,PubMed,10.1016/j.fgb.2013.09.001,,wbshim@neo.tamu.edu,,C Zhang 2013,2013,6 genes,Zhang-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5215,PHI:3835,UniProt,V6QUU6,FGDB,FGSG_00304,,,,Fgrho4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bainong 979,,,spikelet,Rho GTPases,,,,reduced virulence,yes,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24055721,PubMed,10.1016/j.fgb.2013.09.001,,wbshim@neo.tamu.edu,,C Zhang 2013,2013,6 genes,Zhang-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5216,PHI:3836,,no data found,FGDB,FGSG_00304,,,,FgRHO1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,,,,Lethal pathogen phenotype,,,,Rho GTPases,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion; gene complementation,,,RP,24055721,PubMed,10.1016/j.fgb.2013.09.001,,wbshim@neo.tamu.edu,,C Zhang 2013,2013,6 genes,Zhang-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5217,PHI:3837,UniProt,N4XMB0,GenBank,ENI06272,,,ATCC 48331,Sre1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-N,,,leaf,iron-sensitive transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,RP,23980626,PubMed,10.1094/MPMI-02-13-0055-R,,,Cochliobolus heterostrophus is pathogen anamorph name,N Zhang 2013,2013,2 genes,"Zhang-2013-Iron, oxidative stre",Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5218,PHI:3838,UniProt,Q5J7N6,GenBank,AAS64313,,,,ChAp1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-N,,,leaf,redox sensor,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,RP,23980626,PubMed,10.1094/MPMI-02-13-0055-R,,,Cochliobolus heterostrophus is pathogen anamorph name,N Zhang 2013,2013,2 genes,"Zhang-2013-Iron, oxidative stre",Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5219,PHI:3839,UniProt,E9AFP5,GenBank,CBZ13049,,,Friedlin,BBS1,,,,,,,5664,Leishmania major,347515,MHOM/IL/81/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,foot; lymph node,BBSome subunit,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,RP,23998526,PubMed,10.1111/mmi.12383,,helen.price@york.ac.uk,Footpad.,H P Price 2013,2013,1 gene,Price-2013-The Leishmania major,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5220,PHI:3840,UniProt,Q6D930,GenBank,CAG73703,,,SCRI1043,rcpA,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,soft rot (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Van Gogh,,,tuber,regulation of the Flp/Tad pilus,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,RP,24040039,PubMed,10.1371/journal.pone.0073718,,minna.pirhonen@helsinki.fi,,J Nykyri 2013,2013,5 genes,Nykyri-2013-Role and Regulation,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5221,PHI:3841,UniProt,Q6D929,GenBank,CAG73704,,,SCRI1043,rcpB,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,soft rot (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Van Gogh,,,tuber,regulation of the Flp/Tad pilus,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,RP,24040039,PubMed,10.1371/journal.pone.0073718,,minna.pirhonen@helsinki.fi,,J Nykyri 2013,2013,5 genes,Nykyri-2013-Role and Regulation,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5222,PHI:3842,UniProt,Q6D928,GenBank,CAG73705,,,SCRI1043,tadZ,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,soft rot (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Van Gogh,,,tuber,regulation of the Flp/Tad pilus,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,RP,24040039,PubMed,10.1371/journal.pone.0073718,,minna.pirhonen@helsinki.fi,,J Nykyri 2013,2013,5 genes,Nykyri-2013-Role and Regulation,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5223,PHI:3843,UniProt,Q6D927,GenBank,CAG73706,,,SCRI1043,tadA,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,soft rot (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Van Gogh,,,tuber,regulation of the Flp/Tad pilus,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,RP,24040039,PubMed,10.1371/journal.pone.0073718,,minna.pirhonen@helsinki.fi,,J Nykyri 2013,2013,5 genes,Nykyri-2013-Role and Regulation,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5224,PHI:3844,UniProt,K4FJV4,GenBank,AFI88901,,,SCC3193,W5S_0783,,,,,,,55208,Pectobacterium wasabiae,,SCC3193,soft rot (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Van Gogh,,,tuber,regulation of the Flp/Tad pilus,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,RP,24040039,PubMed,10.1371/journal.pone.0073718,,minna.pirhonen@helsinki.fi,,J Nykyri 2013,2013,5 genes,Nykyri-2013-Role and Regulation,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5225,PHI:3845,UniProt,Q6VEX2,GenBank,AAQ93328,,,,bbk46,,,,,,,139,Borreliella burgdorferi,224326,B31,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; joint,virulence factor; to circumvent adaptive immunity,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,RP,24009501,PubMed,10.1371/journal.ppat.1003567,,Mollie.Jewett@ucf. edu,,T C Ellis 2013,2013,1 gene,Ellis-2013-In Vivo Expression T,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5226,PHI:3846,UniProt,O69641,GenBank,AAK48141,,,CDC1551,CcsX,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"thioredoxin, necessary for heme insertion into cytochrome c",,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,RP,24045640,PubMed,10.1128/mBio.00475-13,,sae2004@med.cornell.edu,CcsX mutant was hyperresistant to H2O2,J L Small 2013,2013,1 gene,Small-2013-Perturbation of Cyto,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5227,PHI:3847,UniProt,A7FN30,GenBank,ABS46609,,,IP 31758,tcpYI,,,,,,,633,Yersinia pseudotuberculosis,,488,Far East scarlet-like fever,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,homology to members of the Toll/IL-1 receptor family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24018301,PubMed,10.1016/j.ijmm.2013.08.002,,schubert@med.uni-muenchen.de,,D Nörenberg 2013,2013,1 gene,Norenberg-2013-Molecular analysis o,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5228,PHI:3848,UniProt,Q4WNP9,GenBank,EAL90135,,,Af293,MetR,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,bZip transcription factor involved sulphur metabolism,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24009505,PubMed,10.1371/journal.ppat.1003573,,Sven.Krappmann@uk-erlangen.de,reduced growth under sulphur-starving conditions,J Amich 2013,2013,1 gene,Amich-2013-Regulation of Sulphu,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5229,PHI:3848,UniProt,Q4WNP9,GenBank,EAL90135,,,Af293,MetR,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,bZip transcription factor involved sulphur metabolism,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24009505,PubMed,10.1371/journal.ppat.1003573,,Sven.Krappmann@uk-erlangen.de,reduced growth under sulphur-starving conditions,J Amich 2013,2013,1 gene,Amich-2013-Regulation of Sulphu,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5230,PHI:3848,UniProt,Q4WNP9,GenBank,EAL90135,,,Af293,MetR,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bZip transcription factor involved sulphur metabolism,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24009505,PubMed,10.1371/journal.ppat.1003573,,Sven.Krappmann@uk-erlangen.de,reduced growth under sulphur-starving conditions,J Amich 2013,2013,1 gene,Amich-2013-Regulation of Sulphu,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5231,PHI:3849,UniProt,Q4WUR1,GenBank,EAL91665,,,Af293,CnaA,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,a calmodulin (CaM)-dependent protein phosphatase,,,,reduced virulence,,,,,,,,reduced,,no,sorbitol; caspofungin,sorbitol: CHEBI:30911; caspofungin: CHEBI:474180,,,,,gene mutation: characterised; gene complementation,,,RP,23990785,PubMed,10.1371/journal.ppat.1003564,,bill.steinbach@duke.edu,Mutants were hypersensitive to caspofungin and the mutations were complemented in growth by sorbitol,P R Juvvadi 2013,2013,1 gene,Juvvadi-2013-Phosphorylation of C,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5232,PHI:3850,UniProt,Q4PG70,GenBank,EAK82077,,,521,Umv1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Bantam,,,seedling,velvet protein family regulate sexual and asexual spore production,,,,reduced virulence,,,,,,,reduced,,,no,,,,,,,gene deletion; gene complementation,,,RP,24064149,PubMed,10.1016/j.fgb.2013.09.002,,covert@uga.edu,,B B Karakkat 2013,2013,3 genes,Karakkat-2013-Two members of the U,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5233,PHI:3851,UniProt,Q4PFG7,GenBank,EAK81705,,,521,Umv2,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Bantam,,,seedling,velvet protein family regulate sexual and asexual spore production,,,,reduced virulence,,,,,,,reduced,,,no,,,,,,,gene deletion; gene complementation,,,RP,24064149,PubMed,10.1016/j.fgb.2013.09.002,,covert@uga.edu,,B B Karakkat 2013,2013,3 genes,Karakkat-2013-Two members of the U,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5234,PHI:3852,UniProt,Q4P6R0,GenBank,EAK85207,,,521,Umv3,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Bantam,,,seedling,velvet protein family regulate sexual and asexual spore production,,,,unaffected pathogenicity,,,,,,,wild type,,,no,,,,,,,gene deletion; gene complementation,,,RP,24064149,PubMed,10.1016/j.fgb.2013.09.002,,covert@uga.edu,,B B Karakkat 2013,2013,3 genes,Karakkat-2013-Two members of the U,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5235,PHI:3850,UniProt,Q4PG70,GenBank,EAK82077,,,521,Umv1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Bantam,,,spikelet,velvet protein family regulate sexual and asexual spore production,,,,unaffected pathogenicity,,,,,,,wild type,,,no,,,,,,,gene deletion; gene complementation,,,RP,24064149,PubMed,10.1016/j.fgb.2013.09.002,,covert@uga.edu,,B B Karakkat 2013,2013,3 genes,Karakkat-2013-Two members of the U,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5236,PHI:3851,UniProt,Q4PFG7,GenBank,EAK81705,,,521,Umv2,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Bantam,,,spikelet,velvet protein family regulate sexual and asexual spore production,,,,unaffected pathogenicity,,,,,,,wild type,,,no,,,,,,,gene deletion; gene complementation,,,RP,24064149,PubMed,10.1016/j.fgb.2013.09.002,,covert@uga.edu,,B B Karakkat 2013,2013,3 genes,Karakkat-2013-Two members of the U,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5237,PHI:3852,UniProt,Q4P6R0,GenBank,EAK85207,,,521,Umv3,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Bantam,,,spikelet,velvet protein family regulate sexual and asexual spore production,,,,unaffected pathogenicity,,,,,,,wild type,,,no,,,,,,,gene deletion; gene complementation,,,RP,24064149,PubMed,10.1016/j.fgb.2013.09.002,,covert@uga.edu,,B B Karakkat 2013,2013,3 genes,Karakkat-2013-Two members of the U,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5238,PHI:3853,UniProt,I1RK32,,,,,,FgSWI6,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Mingxian 169,,,spikelet,transcription cofactor,,,,reduced virulence,yes,,,,,reduced,reduced,reduced,wild type,no,carbendazim,"carbendazim: CHEBI:3392, CAS:10605-21-7",,,,,gene deletion; gene complementation,,,RP,23994322,PubMed,10.1016/j.fgb.2013.08.010,,linghuojiang@jiangnan.edu.cn,Deletion of FgSWI6 causes mycelium of F. graminearum become sensitive to MBC in liquid medium.,N Liu 2013,2013,1 gene,Liu-2013-The transcription co,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5239,PHI:3854,UniProt,Q4PE31,GenBank,EAK82413,,,521,um01632,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Bantam,,,seedling,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,RP,23973481,PubMed,10.1016/j.fgb.2013.08.006,,barrysaville@trentu.ca,,M E Donaldson 2013,2013,3 genes,Donaldson-2013-Investigating the Us,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5240,PHI:3855,UniProt,Q4PA17,GenBank,EAK84047,,,521,zig1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Bantam,,,seedling,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,RP,23973481,PubMed,10.1016/j.fgb.2013.08.006,,barrysaville@trentu.ca,,M E Donaldson 2013,2013,3 genes,Donaldson-2013-Investigating the Us,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5241,PHI:3856,,no data found,MUMDB,um10226,,,,cnb1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Bantam,,,seedling,calcineurin regulator y B subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23973481,PubMed,10.1016/j.fgb.2013.08.006,,barrysaville@trentu.ca,,M E Donaldson 2013,2013,3 genes,Donaldson-2013-Investigating the Us,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5242,PHI:3857,UniProt,Q59QP1,GenBank,EAK92775,,,SC5314,CaCrg1,,,,,,,5476,Candida albicans,,,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,small molecule methyltransferase,,,sphingolipid pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24083538,PubMed,10.1021/cb400607h,,corey.nislow@ubc.ca,,E Lissina 2013,2013,1 gene,Lissina-2013-A Novel Small Molecu,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5243,PHI:3858,UniProt,D2TT37,GenBank,CBG87859,,,ICC168,nleB,,,,,,,67825,Citrobacter rodentium,,ICC169,gastrointestinal disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon; spleen,type III effector,,,FAS signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24025841,PubMed,10.1038/nature12524,,hartland@unimelb.edu.au,,J S Pearson 2013,2013,1 gene,Pearson-2013-A type III effector,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5244,PHI:3859,UniProt,B2W4L0,GenBank,EDU47467,,,Pt-1C-BFP,GLU1,,,,,,,45151,Pyrenophora tritici-repentis,,Alg3-24,tan spot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Erik,,,leaf,glucanase gene,,,,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24119405,PubMed,10.1016/j.funbio.2013.07.003,,stephen.strelkov@ualberta.ca,,H Fu 2013,2013,1 gene,"Fu-2013-An exo-1,3-beta-gluc",Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5245,PHI:3859,UniProt,B2W4L0,GenBank,EDU47467,,,Pt-1C-BFP,GLU1,,,,,,,45151,Pyrenophora tritici-repentis,,Alg3-24,tan spot,monocots,4565,Triticum aestivum (related: bread wheat),cv. 6B662,,,leaf,glucanase gene,,,,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24119405,PubMed,10.1016/j.funbio.2013.07.003,,stephen.strelkov@ualberta.ca,,H Fu 2013,2013,1 gene,"Fu-2013-An exo-1,3-beta-gluc",Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5246,PHI:3860,UniProt,E1XHG4,GenBank,CBW33751,,,INV200,PspA,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),MF1,,,brain,surface protein and virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,RP,24059458,PubMed,10.1186/1471-2334-13-444,,susanna.ricci@unisi.it,,S Ricci 2013,2013,2 genes,Ricci-2013-Contribution of diff,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5247,PHI:3861,UniProt,B5E3T5,GenBank,ACF56456,,,G54,PspC,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),MF1,,,brain,surface protein and virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,RP,24059458,PubMed,10.1186/1471-2334-13-444,,susanna.ricci@unisi.it,,S Ricci 2013,2013,2 genes,Ricci-2013-Contribution of diff,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5248,PHI:3862,UniProt,I1RZP6,GenBank,XM_390073,,,PH-1,FgSNF1,,,,,,,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,sucrose non-fermenting 1 protein kinase complex genes,,,,reduced virulence,,,,,,,wild type,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24057127,PubMed,10.1007/s00294-013-0409-7,,lee2443@snu.ac.kr,,J Yu 2013,2013,3 genes,Yu-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5249,PHI:3863,UniProt,I1RTA6,GenBank,XM_387583,,,PH-1,FgGAL83,,,,,,,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,sucrose non-fermenting 1 protein kinase complex genes,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24057127,PubMed,10.1007/s00294-013-0409-7,,lee2443@snu.ac.kr,,J Yu 2013,2013,3 genes,Yu-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5250,PHI:3864,,no data found,FGDB,FGSG_17145,,,,FgSNF4,,,,,,,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,sucrose non-fermenting 1 protein kinase complex genes,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24057127,PubMed,10.1007/s00294-013-0409-7,,lee2443@snu.ac.kr,,J Yu 2013,2013,3 genes,Yu-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5251,PHI:3862,UniProt,I1RZP6,GenBank,XM_390073,,,PH-1,FgSNF1,,,,,,PHI:3863; PHI:3864,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,sucrose non-fermenting 1 protein kinase complex genes,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24057127,PubMed,10.1007/s00294-013-0409-7,,lee2443@snu.ac.kr,,J Yu 2013,2013,3 genes,Yu-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5252,PHI:3863,UniProt,I1RTA6,GenBank,XM_387583,,,PH-1,FgGAL83,,,,,,PHI:3862; PHI:3864,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,sucrose non-fermenting 1 protein kinase complex genes,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24057127,PubMed,10.1007/s00294-013-0409-7,,lee2443@snu.ac.kr,,J Yu 2013,2013,3 genes,Yu-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5253,PHI:3864,,no data found,FGDB,FGSG_17145,,,,FgSNF4,,,,,,PHI:3862; PHI:3863,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,sucrose non-fermenting 1 protein kinase complex genes,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24057127,PubMed,10.1007/s00294-013-0409-7,,lee2443@snu.ac.kr,,J Yu 2013,2013,3 genes,Yu-2013-Functional character,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5254,PHI:3865,UniProt,A3RH09,GenBank,GQ324948,,,,GOX2,,,,,,,27334,Penicillium expansum,,Pe-21,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,oxidation of beta9D9glucose to D9glucono9delta954 lactone and H2O2 is catalyzed by this glucose oxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24024763,PubMed,10.1094/MPMI-05-13-0138-R,,dovprusk@volcani.agri.gov.il,,S Barad 2013,2013,3 genes,Barad-2013-Accumulation of the,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5255,PHI:3866,UniProt,Q4JIM2,GenBank,DQ084388,,,,IDH,,,,,,,27334,Penicillium expansum,,Pe-21,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,isoepoxyedon dehydrogenase,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24024763,PubMed,10.1094/MPMI-05-13-0138-R,,dovprusk@volcani.agri.gov.il,,S Barad 2013,2013,3 genes,Barad-2013-Accumulation of the,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5256,PHI:3867,UniProt,Q874A5,GenBank,AY225524,,,,PACC,,,,,,,27334,Penicillium expansum,,Pe-21,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,pH-response transcription factor pacC/RIM101,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24024763,PubMed,10.1094/MPMI-05-13-0138-R,,dovprusk@volcani.agri.gov.il,,S Barad 2013,2013,3 genes,Barad-2013-Accumulation of the,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5257,PHI:3868,,no data found,GenBank,DY543081,,,,AbDhn1,,,,,,,29001,Alternaria brassicicola,,Abra43,black spot,eudicots,3712,Brassica oleracea (no common name found),cv. Bartolo,,,leaf; silique,dehydrin-like proteins,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion,,,RP,24098369,PubMed,10.1371/journal.pone.0075143,,thomas.guillemette@univ-angers.fr,,S Pochon 2013,2013,3 genes,Pochon-2013-Dehydrin-like Protei,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5258,PHI:3869,UniProt,L0BVZ0,GenBank,JX891381,,,,AbDhn2,,,,,,,29001,Alternaria brassicicola,,Abra43,black spot,eudicots,3712,Brassica oleracea (no common name found),cv. Bartolo,,,leaf; silique,dehydrin-like proteins,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion,,,RP,24098369,PubMed,10.1371/journal.pone.0075143,,thomas.guillemette@univ-angers.fr,,S Pochon 2013,2013,3 genes,Pochon-2013-Dehydrin-like Protei,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5259,PHI:3870,UniProt,L0BUT7,GenBank,JX891382,,,,AbDhn3,,,,,,,29001,Alternaria brassicicola,,Abra43,black spot,eudicots,3712,Brassica oleracea (no common name found),cv. Bartolo,,,leaf; silique,dehydrin-like proteins,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion,,,RP,24098369,PubMed,10.1371/journal.pone.0075143,,thomas.guillemette@univ-angers.fr,,S Pochon 2013,2013,3 genes,Pochon-2013-Dehydrin-like Protei,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5260,PHI:3868,,no data found,GenBank,DY543081,,,,AbDhn1,,,,,,PHI:3869,29001,Alternaria brassicicola,,Abra43,black spot,eudicots,3712,Brassica oleracea (no common name found),cv. Bartolo,,,leaf; silique,dehydrin-like proteins,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion,,,RP,24098369,PubMed,10.1371/journal.pone.0075143,,thomas.guillemette@univ-angers.fr,,S Pochon 2013,2013,3 genes,Pochon-2013-Dehydrin-like Protei,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5261,PHI:3869,UniProt,L0BVZ0,GenBank,JX891381,,,,AbDhn2,,,,,,PHI:3868,29001,Alternaria brassicicola,,Abra43,black spot,eudicots,3712,Brassica oleracea (no common name found),cv. Bartolo,,,leaf; silique,dehydrin-like proteins,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion,,,RP,24098369,PubMed,10.1371/journal.pone.0075143,,thomas.guillemette@univ-angers.fr,,S Pochon 2013,2013,3 genes,Pochon-2013-Dehydrin-like Protei,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5262,PHI:3871,UniProt,Q4Q9C3,GenBank,XP_001684075,,,Friedlin,SKa,,,,,,,5664,Leishmania major,347515,MHOM/IL/81/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,foot; lymph node,catalysing the conversion of sphingosine or dihydrosphingosine into sphingosine-1-phosphate or dihydrosphingosine-1-phosphate respectively,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,23980754,PubMed,10.1111/mmi.12378,,kai.zhang@ttu.edu,Footpad.,O Zhang 2013,2013,1 gene,Zhang-2013-Sphingosine kinase A,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5263,PHI:3872,UniProt,P64829,GenBank,AAK45663,,,CDC1551,pde,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"synthesis of the ubiquitous bacterial second messenger, cyclic di-GMP",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,RP,24080120,PubMed,10.1016/j.tube.2013.09.002,,lichuanyou6688@hotmail.com,"dgc mutants and Delta pde exhibited increased and reduced dormancy, respectively, in both anaerobiosis-trig gered and vitamin C-triggered in vitro dormancy models",Y Hong 2013,2013,2 genes,Hong-2013-Cyclic di-GMP mediat,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5264,PHI:3873,UniProt,P64825,GenBank,AAK45660,,,CDC1551,dgc,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"degradation of the ubiquitous bacterial second messenger, cyclic di-GMP",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,24080120,PubMed,10.1016/j.tube.2013.09.002,,lichuanyou6688@hotmail.com,"dgc mutants and Delta pde exhibited increased and reduced dormancy, respectively, in both anaerobiosis-trig gered and vitamin C-triggered in vitro dormancy models",Y Hong 2013,2013,2 genes,Hong-2013-Cyclic di-GMP mediat,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5265,PHI:3874,UniProt,S8F4I7,GenBank,EPT29597,,,ME49,ROP47,,,,,,,5811,Toxoplasma gondii,,,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain,rhoptry bulb protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion,,,RP,24070999,PubMed,10.1016/j.ijpara.2013.08.002,,jsaeij@mit.edu,,A Camejo 2013,2013,3 genes,Camejo-2013-Identification of th,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5266,PHI:3875,UniProt,S8ER10,GenBank,EPT24697,,,ME49,ROP48,,,,,,,5811,Toxoplasma gondii,,,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain,rhoptry bulb protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion,,,RP,24070999,PubMed,10.1016/j.ijpara.2013.08.002,,jsaeij@mit.edu,,A Camejo 2013,2013,3 genes,Camejo-2013-Identification of th,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5267,PHI:3876,UniProt,S8GNY9,GenBank,EPT30274,,,ME49,TGME49_201860,,,,,,,5811,Toxoplasma gondii,,,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain,rhoptry protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion,,,RP,24070999,PubMed,10.1016/j.ijpara.2013.08.002,,jsaeij@mit.edu,,A Camejo 2013,2013,3 genes,Camejo-2013-Identification of th,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5268,PHI:3877,UniProt,Q8CVF8,GenBank,AE016771_333,,,CFT073,FimH,,,,,,,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder,type 1 adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24003161,PubMed,10.1073/pnas.1315203110,,hultgren@borcim.wustl.edu,"variants, which maintain a high-affinity conformation in the imCGHtip-like structure are attenuated in their infection",D J Schwartz 2013,2013,1 gene,Schwartz-2013-Positively selected,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5269,PHI:3878,UniProt,Q8ZLT3,GenBank,AAL22154,,,LT2,pnp,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain X4232,food poisoning,even-toed ungulates,9823,Sus scrofa (related: pig),,,,tonsil; lymph node; Peyer's gland; cecum,"polynucleotide phosphorylase, an exoribonuclease involved in RNA processing and degradation",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24126127,PubMed,10.1016/j.micpath.2013.10.001,,shawn.bearson@ars.usda.gov,,S M D Bearson 2013,2013,1 gene,Bearson-2013-Polynucleotide phosp,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5270,PHI:3879,UniProt,E4TDA5,GenBank,ADQ82764,,,ATCC 11845,tbdR1,,,,,,,34085,Riemerella anatipestifer,1354240,serotype 1 strain CH3,,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood; liver; brain,TonB-dependent receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24075356,PubMed,10.1016/j.vetmic.2013.08.020,,huqinghai@caas.cn,,F Lu 2013,2013,1 gene,Lu-2013-The role of TonB-dep,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5271,PHI:3880,UniProt,B8N3U5,GenBank,EED55907,,,NRRL3357,MeaB,,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,aflatoxicosis,eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,bZip encoding,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24040154,PubMed,10.1371/journal.pone.0074030,,npkeller@wisc.edu,,S Amaike 2013,2013,2 genes,Amaike-2013-The bZIP Protein Mea,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5272,PHI:3880,UniProt,B8N3U5,GenBank,EED55907,,,NRRL3357,MeaB,,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,aflatoxicosis,eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,bZip encoding,,,,unaffected pathogenicity,,,,,,reduced,,wild type,,no,,,,,,,gene deletion,,,RP,24040154,PubMed,10.1371/journal.pone.0074030,,npkeller@wisc.edu,,S Amaike 2013,2013,2 genes,Amaike-2013-The bZIP Protein Mea,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5273,PHI:3881,UniProt,Q2KNE4,GenBank,AAX68412,,,ATCC 200026,LaeA,,,,,,PHI:3880,5059,Aspergillus flavus,332952,NRRL 3357,aflatoxicosis,eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,methyltransferase and fungal specific virulence factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24040154,PubMed,10.1371/journal.pone.0074030,,npkeller@wisc.edu,,S Amaike 2013,2013,2 genes,Amaike-2013-The bZIP Protein Mea,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5274,PHI:3880,UniProt,B8N3U5,GenBank,EED55907,,,NRRL3357,MeaB,,,,,,PHI:3881,5059,Aspergillus flavus,332952,NRRL 3357,aflatoxicosis,eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,bZip encoding,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24040154,PubMed,10.1371/journal.pone.0074030,,npkeller@wisc.edu,,S Amaike 2013,2013,2 genes,Amaike-2013-The bZIP Protein Mea,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5275,PHI:3882,UniProt,K4LAY3,GenBank,AFV08857,,,ITCC BB0001,XopN,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO1,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,root,type 3 secretion system effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24086651,PubMed,10.1371/journal.pone.0075867,,sonti@ccmb.res.in,A. Tumefaciens strain EHA101,,2013,4 genes,Sinha-2013-Cell Wall Degrading,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5276,PHI:3883,UniProt,R4TJS0,GenBank,AGM16438,,,ITCC BB0001,XopQ,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO1,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,root,type 3 secretion system effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24086651,PubMed,10.1371/journal.pone.0075867,,sonti@ccmb.res.in,A. Tumefaciens strain EHA101,,2013,4 genes,Sinha-2013-Cell Wall Degrading,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5277,PHI:3884,UniProt,B2SJG5,GenBank,ACD57163,,,ITCC BB0001,XopX,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO1,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,root,type 3 secretion system effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24086651,PubMed,10.1371/journal.pone.0075867,,sonti@ccmb.res.in,A. Tumefaciens strain EHA101,,2013,4 genes,Sinha-2013-Cell Wall Degrading,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5278,PHI:3885,UniProt,G7TFJ1,GenBank,AEQ96548,,,,XopZ,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO1,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,root,type 3 secretion system effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24086651,PubMed,10.1371/journal.pone.0075867,,sonti@ccmb.res.in,A. Tumefaciens strain EHA101,,2013,4 genes,Sinha-2013-Cell Wall Degrading,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5279,PHI:3882,UniProt,K4LAY3,GenBank,AFV08857,,,ITCC BB0001,XopN,,,,,,PHI:3884,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO1,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,root,type 3 secretion system effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24086651,PubMed,10.1371/journal.pone.0075867,,sonti@ccmb.res.in,A. Tumefaciens strain EHA101,,2013,4 genes,Sinha-2013-Cell Wall Degrading,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5280,PHI:3884,UniProt,B2SJG5,GenBank,ACD57163,,,ITCC BB0001,XopX,,,,,,PHI:3882,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO1,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,root,type 3 secretion system effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24086651,PubMed,10.1371/journal.pone.0075867,,sonti@ccmb.res.in,A. Tumefaciens strain EHA101,,2013,4 genes,Sinha-2013-Cell Wall Degrading,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5281,PHI:3882,UniProt,K4LAY3,GenBank,AFV08857,,,ITCC BB0001,XopN,,,,,,PHI:3883; PHI:3884; PHI:3885,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO1,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,root,type 3 secretion system effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24086651,PubMed,10.1371/journal.pone.0075867,,sonti@ccmb.res.in,A. Tumefaciens strain EHA101,,2013,4 genes,Sinha-2013-Cell Wall Degrading,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5282,PHI:3883,UniProt,R4TJS0,GenBank,AGM16438,,,ITCC BB0001,XopQ,,,,,,PHI:3882; PHI:3884; PHI:3885,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO1,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,root,type 3 secretion system effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24086651,PubMed,10.1371/journal.pone.0075867,,sonti@ccmb.res.in,A. Tumefaciens strain EHA101,,2013,4 genes,Sinha-2013-Cell Wall Degrading,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5283,PHI:3884,UniProt,B2SJG5,GenBank,ACD57163,,,ITCC BB0001,XopX,,,,,,PHI:3882; PHI:3883; PHI:3885,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO1,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,root,type 3 secretion system effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24086651,PubMed,10.1371/journal.pone.0075867,,sonti@ccmb.res.in,A. Tumefaciens strain EHA101,,2013,4 genes,Sinha-2013-Cell Wall Degrading,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5284,PHI:3885,UniProt,G7TFJ1,GenBank,AEQ96548,,,,XopZ,,,,,,PHI:3882; PHI:3883; PHI:3884,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO1,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,root,type 3 secretion system effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24086651,PubMed,10.1371/journal.pone.0075867,,sonti@ccmb.res.in,A. Tumefaciens strain EHA101,,2013,4 genes,Sinha-2013-Cell Wall Degrading,Batch032,2013-11-01,MC,,,,,,,,,,,,,
,,Record 5285,PHI:3886,UniProt,W7LZA5,BROAD,FVEG_01321.5,,,7600,UBL1,chromosome 1,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays,,,kernel; spikelet,encoding a UBR-box/RING domain E3 ubiquitin ligase,,,N-end rule pathway,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,24237664,PubMed,10.1111/1462-2920.12333,,bbluhm@uark.edu,,J B Ridenour 2013,2013,2 genes,Ridenour-2013-UBL1 of Fusarium ver,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5286,PHI:3887,UniProt,I1RC91,BROAD,FGSG_01194.3,,,PH1,UBL1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays,,,kernel; spikelet,encoding a UBR-box/RING domain E3 ubiquitin ligase,,,N-end rule pathway,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,24237664,PubMed,10.1111/1462-2920.12333,,bbluhm@uark.edu,,J B Ridenour 2013,2013,2 genes,Ridenour-2013-UBL1 of Fusarium ver,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5287,PHI:3886,UniProt,W7LZA5,BROAD,FVEG_01321.5,,,,UBL1,chromosome 1,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,encoding a UBR-box/RING domain E3 ubiquitin ligase,,,N-end rule pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24237664,PubMed,10.1111/1462-2920.12333,,bbluhm@uark.edu,,J B Ridenour 2013,2013,2 genes,Ridenour-2013-UBL1 of Fusarium ver,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5288,PHI:3887,UniProt,I1RC91,BROAD,FGSG_01194.3,,,PH1,UBL1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,encoding a UBR-box/RING domain E3 ubiquitin ligase,,,N-end rule pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24237664,PubMed,10.1111/1462-2920.12333,,bbluhm@uark.edu,,J B Ridenour 2013,2013,2 genes,Ridenour-2013-UBL1 of Fusarium ver,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5289,PHI:3888,,no data found,,,,,,IesR-1,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SV5015,food poisoning,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,antisense RNA encoded in the S. typhimurium pSLT virulence plasmid that is specifically up-regulated by non-growing dormant bacteria persisting inside fibroblasts.,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24205037,PubMed,10.1371/journal.pone.0077939,,fgportillo@cnb.csic.es,,J Gonzalo-Asensio 2013,2013,1 gene,Gonzalo-Asensio-2013-A Novel Antisense RN,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5290,PHI:3889,UniProt,E9DS25,GenBank,EFY93607,,,CQMa102,MaMk1,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),,,,,Fus3/Kss1-type mitogen-activated protein kinase (MAPK) gene,,,,loss of pathogenicity,,yes,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24184951,PubMed,10.1016/j.jip.2013.10.014,,yuxianxia@cqu.edu.cn,,K Jin 2013,2013,1 gene,"Jin-2013-MaMk1, a FUS3_KSS1-t",Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5291,PHI:3890,UniProt,Q8FYM1,GenBank,AAN30741,,,1330,BtaF,,,,,,,29461,Brucella suis,204722,1330,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,trimeric autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24236157,PubMed,10.1371/journal.pone.0079770,,azorreguieta@leloir.org.ar,,V Ruiz-Ranwez 2013,2013,2 genes,Ruiz-Ranwez-2013-The BtaF Trimeric Au,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5292,PHI:3891,UniProt,Q8G378,GenBank,AAN29029,,,1330,BtaE,,,,,,,29461,Brucella suis,204722,1330,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,trimeric autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24236157,PubMed,10.1371/journal.pone.0079770,,azorreguieta@leloir.org.ar,,V Ruiz-Ranwez 2013,2013,2 genes,Ruiz-Ranwez-2013-The BtaF Trimeric Au,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5293,PHI:3890,UniProt,Q8FYM1,GenBank,AAN30741,,,1330,BtaF,,,,,,PHI:3891,29461,Brucella suis,204722,1330,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,trimeric autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24236157,PubMed,10.1371/journal.pone.0079770,,azorreguieta@leloir.org.ar,,V Ruiz-Ranwez 2013,2013,2 genes,Ruiz-Ranwez-2013-The BtaF Trimeric Au,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5294,PHI:3891,UniProt,Q8G378,GenBank,AAN29029,,,1330,BtaE,,,,,,PHI:3890,29461,Brucella suis,204722,1330,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,trimeric autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24236157,PubMed,10.1371/journal.pone.0079770,,azorreguieta@leloir.org.ar,,V Ruiz-Ranwez 2013,2013,2 genes,Ruiz-Ranwez-2013-The BtaF Trimeric Au,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5295,PHI:3892,UniProt,J9MR80,BROAD,FOXG_05408,,,4287,FoEBR1,chromosome 7,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,putative transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24237614,PubMed,10.1111/1462-2920.12331,,hckist@umn.edu,,W Jonkers 2013,2013,2 genes,Jonkers-2013-EBR1 genomic expansi,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5296,PHI:3893,UniProt,A0A0E0RVW9,EMBL,FGRAMPH1_01T07179,,,PH-1,FgEBR1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,putative transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,24237614,PubMed,10.1111/1462-2920.12331,,hckist@umn.edu,,W Jonkers 2013,2013,2 genes,Jonkers-2013-EBR1 genomic expansi,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5297,PHI:3894,UniProt,B2SN05,GenBank,ACD57567,,,PXO99A,Prc,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,PDZ domain-containing proteases,,,,reduced virulence,,,,,,,,,,no,H2O2; SDS,H2O2: CHEBI:16240; sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene disruption; gene complementation,,,RP,24200074,PubMed,10.1094/MPMI-08-13-0234-R,,qianw@im.ac.cn,"Mutation of prc resulted in susceptibility to multiple environmental stresses, including H2O2, sodium dodecylsulfate, and osmolarity stresses.",C Deng 2013,2013,2 genes,Deng-2013-The Periplasmic PDZ,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5298,PHI:3895,UniProt,B2SR06,GenBank,ACD59567,,,PXO99A,PXO_01122,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,PDZ domain-containing proteases,,,,reduced virulence,,,,,,,,,,no,H2O2; SDS,H2O2: CHEBI:16240; sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene disruption; gene complementation,,,RP,24200074,PubMed,10.1094/MPMI-08-13-0234-R,,qianw@im.ac.cn,"Mutation of prc resulted in susceptibility to multiple environmental stresses, including H2O2, sodium dodecylsulfate, and osmolarity stresses.",C Deng 2013,2013,2 genes,Deng-2013-The Periplasmic PDZ,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5299,PHI:3896,UniProt,D0E2X6,GenBank,GQ292557,,,,Clt-1,,,,,,,5503,Curvularia lunata,1263492,CX-3,Curvularia leaf spot,monocots,4577,Zea mays (related: maize),subsp. mays cv. Huangzao 4,,,leaf,product-a non host specific toxin known as methyl 5 (hydroxymethyl) furan 2 carboxylate (M5HF2C),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24134718,PubMed,10.1094/PHYTO-07-13-0190-R,,jiechen59@sjtu.edu.cn,mutants produced no detectable M5HF2C. Cochliobolus lunatus is pathogen anamorph name.,J Gao 2013,2013,1 gene,Gao-2013-Insertional Mutagene,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5300,PHI:3897,UniProt,Q63KC3,GenBank,CAH38912,,,K96243,bpss1439,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,encoding a predicted trimeric autotransporter adhesin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,24223950,PubMed,10.1371/journal.pone.0079461,,eg98@leicester.ac.uk,,N R L Adler 2013,2013,1 gene,Lazar Adler-2013-Identification of a,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5301,PHI:3898,UniProt,Q04HU1,GenBank,ABJ54994,,,D39,HtrA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; liver,serine protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,24244609,PubMed,10.1371/journal.pone.0080062,,s.f.destoppelaar@amc.uva.nl,,S F de Stoppelaar 2013,2013,3 genes,de Stoppelaar-2013-Streptococcus pneumo,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5302,PHI:3899,UniProt,Q04LP0,GenBank,ABJ55268,,,D39,PrtA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; liver,serine protease,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,24244609,PubMed,10.1371/journal.pone.0080062,,s.f.destoppelaar@amc.uva.nl,,S F de Stoppelaar 2013,2013,3 genes,de Stoppelaar-2013-Streptococcus pneumo,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5303,PHI:3900,UniProt,Q04IL2,GenBank,ABJ54257,,,D39,SFP,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; liver,serine protease,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,24244609,PubMed,10.1371/journal.pone.0080062,,s.f.destoppelaar@amc.uva.nl,,S F de Stoppelaar 2013,2013,3 genes,de Stoppelaar-2013-Streptococcus pneumo,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5304,PHI:3901,UniProt,Q4WTR6,GenBank,EAL92010,,,Af293,afmid1,chromosome V,,,,,,746128,Aspergillus fumigatus,,A1160,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,stretch-activated ion channel,,,,reduced virulence,,,,,,,,reduced; aberrant,reduced,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion; gene complementation,,,RP,24239700,PubMed,10.1016/j.fgb.2013.11.003,,linglu@njnu.edu.cn,The mutant Delta afmid1 demonstrated more sensitivity to oxidative agent s (H2O 2 and Menadione) than wild type.,H Jiang 2013,2013,1 gene,Jiang-2013-Deletion of the puta,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5305,PHI:3902,UniProt,Q96UQ6,GenBank,AF435120_1,,,,AGS1,,,,,,PHI:3903; PHI:3904,746128,Aspergillus fumigatus,,ku80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,"controlling the biosynthesis of a-(1,3)-glucan",,,,reduced virulence,,,,,,aberrant,,wild type,wild type,no,H2O2; SDS; lactoferrin; LL-37; cathelicidin; aHNP2; bhBD2,H2O2: CHEBI:16240; sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion,,,RP,24244155,PubMed,10.1371/journal.ppat.1003716,,anne.beauvais@pasteur.fr,different inhibitors in combination did not result in a differentialsensitivity between the parental and mutant strains.,A Beauvais 2013,2013,3 genes,Beauvais-2013-Deletion of the alph,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5306,PHI:3903,UniProt,Q96UR0,GenBank,AF432352_1,,,,AGS2,,,,,,PHI:3902; PHI:3904,746128,Aspergillus fumigatus,,ku80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,"controlling the biosynthesis of a-(1,3)-glucan",,,,reduced virulence,,,,,,aberrant,,wild type,wild type,no,H2O2; SDS; lactoferrin; LL-37; cathelicidin; aHNP2; bhBD2,H2O2: CHEBI:16240; sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion,,,RP,24244155,PubMed,10.1371/journal.ppat.1003716,,anne.beauvais@pasteur.fr,different inhibitors in combination did not result in a differentialsensitivity between the parental and mutant strains.,A Beauvais 2013,2013,3 genes,Beauvais-2013-Deletion of the alph,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5307,PHI:3904,UniProt,Q4WRQ8,GenBank,EAL90874,,,Af293,AGS3,,,,,,PHI:3902; PHI:3903,746128,Aspergillus fumigatus,,ku80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,"controlling the biosynthesis of a-(1,3)-glucan",,,,reduced virulence,,,,,,aberrant,,wild type,wild type,no,H2O2; SDS; lactoferrin; LL-37; cathelicidin; aHNP2; bhBD2,H2O2: CHEBI:16240; sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion,,,RP,24244155,PubMed,10.1371/journal.ppat.1003716,,anne.beauvais@pasteur.fr,different inhibitors in combination did not result in a differentialsensitivity between the parental and mutant strains.,A Beauvais 2013,2013,3 genes,Beauvais-2013-Deletion of the alph,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5308,PHI:3905,UniProt,Q9EYH7,GenBank,AF324349_2,,,YPIII,CNFy,,,,,,,633,Yersinia pseudotuberculosis,502800,YPIII,gastrointestinal disease; yersiniosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lymph node,cytotoxic necrotizing factor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,RP,24244167,PubMed,10.1371/journal.ppat.1003746,,petra.dersch@helmholtz-hzi.de,,J Schweer 2013,2013,1 gene,Schweer-2013-The Cytotoxic Necrot,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5309,PHI:3906,UniProt,Q0PAA2,GenBank,CAL34916,,,11168,CiaD,,,,,,,197,Campylobacter jejuni,192222,11168,campylobacteriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-10<-/->),,,gastrointestinal tract,type 3 secretion system effectors,,,MAP kinase signaling pathways,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24144181,PubMed,10.1186/1478-811X-11-79,,konkel@vetmed.wsu.edu,,D R Samuelson 2013,2013,1 gene,Samuelson-2013-The Campylobacter je,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5310,PHI:3907,UniProt,D3W9Z8,GenBank,ADC97456,,,AF14,ZrfC,,,,,,,746128,Aspergillus fumigatus,,Af14,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),SPF CD-1,,,lung,alkaline zinc transporter,,,MAP kinase signaling pathways,reduced virulence,,,,,,,,reduced,,no,calprotectin,,,,,,gene mutation; gene complementation,,,RP,24245710,PubMed,10.1111/cmi.12238,,jacalera@usal.es,"under Zn- and/or Mn-limiting conditions zrfC enables A. fumigatus to grow in the presence of calprotectin, which is detected in fungal abscesses of non-leucopenic animals",J Amich 2013,2013,3 genes,Amich-2013-The ZrfC alkaline zi,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5311,PHI:3908,UniProt,Q6IZ78,GenBank,AAT11930,,,,ZrfA,,,,,,,746128,Aspergillus fumigatus,,Af14,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),SPF CD-1,,,lung,alkaline zinc transporter,,,MAP kinase signaling pathways,reduced virulence,,,,,,,,reduced,,no,calprotectin,,,,,,gene mutation; gene complementation,,,RP,24245710,PubMed,10.1111/cmi.12238,,jacalera@usal.es,"under Zn- and/or Mn-limiting conditions zrfC enables A. fumigatus to grow in the presence of calprotectin, which is detected in fungal abscesses of non-leucopenic animals",J Amich 2013,2013,3 genes,Amich-2013-The ZrfC alkaline zi,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5312,PHI:3909,UniProt,Q6IZ77,GenBank,AAT11931,,,,ZrfB,,,,,,,746128,Aspergillus fumigatus,,Af14,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),SPF CD-1,,,lung,alkaline zinc transporter,,,MAP kinase signaling pathways,reduced virulence,,,,,,,,reduced,,no,calprotectin,,,,,,gene mutation; gene complementation,,,RP,24245710,PubMed,10.1111/cmi.12238,,jacalera@usal.es,"under Zn- and/or Mn-limiting conditions zrfC enables A. fumigatus to grow in the presence of calprotectin, which is detected in fungal abscesses of non-leucopenic animals",J Amich 2013,2013,3 genes,Amich-2013-The ZrfC alkaline zi,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5313,PHI:3907,UniProt,D3W9Z8,GenBank,ADC97456,,,AF14,ZrfC,,,,,,PHI:3908; PHI:3909,746128,Aspergillus fumigatus,,Af14,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),SPF CD-1,,,lung,alkaline zinc transporter,,,MAP kinase signaling pathways,loss of pathogenicity,,,,,,,,reduced,,no,calprotectin,,,,,,gene mutation; gene complementation,,,RP,24245710,PubMed,10.1111/cmi.12238,,jacalera@usal.es,"under Zn- and/or Mn-limiting conditions zrfC enables A. fumigatus to grow in the presence of calprotectin, which is detected in fungal abscesses of non-leucopenic animals",J Amich 2013,2013,3 genes,Amich-2013-The ZrfC alkaline zi,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5314,PHI:3908,UniProt,Q6IZ78,GenBank,AAT11930,,,,ZrfA,,,,,,PHI:3907; PHI:3909,746128,Aspergillus fumigatus,,Af14,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),SPF CD-1,,,lung,alkaline zinc transporter,,,MAP kinase signaling pathways,loss of pathogenicity,,,,,,,,reduced,,no,calprotectin,,,,,,gene mutation; gene complementation,,,RP,24245710,PubMed,10.1111/cmi.12238,,jacalera@usal.es,"under Zn- and/or Mn-limiting conditions zrfC enables A. fumigatus to grow in the presence of calprotectin, which is detected in fungal abscesses of non-leucopenic animals",J Amich 2013,2013,3 genes,Amich-2013-The ZrfC alkaline zi,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5315,PHI:3909,UniProt,Q6IZ77,GenBank,AAT11931,,,,ZrfB,,,,,,PHI:3907; PHI:3908,746128,Aspergillus fumigatus,,Af14,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),SPF CD-1,,,lung,alkaline zinc transporter,,,MAP kinase signaling pathways,loss of pathogenicity,,,,,,,,reduced,,no,calprotectin,,,,,,gene mutation; gene complementation,,,RP,24245710,PubMed,10.1111/cmi.12238,,jacalera@usal.es,"under Zn- and/or Mn-limiting conditions zrfC enables A. fumigatus to grow in the presence of calprotectin, which is detected in fungal abscesses of non-leucopenic animals",J Amich 2013,2013,3 genes,Amich-2013-The ZrfC alkaline zi,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5316,PHI:3910,UniProt,I1R9N5,GenBank,XM_380362,,,PH-1,FgSAT,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spike,serine O-acetyltransferase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,pyrimethanil; tebuconazole; triadimefon; O-acetylserine; cysteine; methionine; serine,cysteine: CHEBI:15356; methionine: CHEBI:16811; serine: CHEBI:17822,,,,,gene disruption; gene complementation,,,RP,24197784,PubMed,10.1007/s11274-013-1544-5,,fujing7359583@163.com,"Supplementation of O-acetylserine,cysteine, or methionine, but not serine, rescued the defect of mycelial growth in FgSAT deletion mutants / Virulence, deoxynivalenol production and fungicide sensitivity assays found that the three mutants showed no significant difference from wild-type progenitor PH-1.",J Fu 2013,2013,1 gene,Fu-2013-Serine O-acetyltrans,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5317,PHI:3911,UniProt,Q04LM7,GenBank,ABJ55360,,,D39,Etrx1,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung; blood; nasopharynx,surface-exposed thioredoxin-family lipoprotein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; paraquat,"H2O2: CHEBI:16240; paraquat, : CHEBI:34905",,,,,gene mutation,,,RP,24136784,PubMed,10.1002/emmm.201202435,,xjuan@iqfr.csic.es,"both Etrx1 and Etrx2 can function as redox partners for SpMsrAB2 since the inactivation of both Etrx proteins or SpMsrAB2 renders pneumococci, to varying degrees, sensitive to extracellular peroxide stress.",M Saleh 2013,2013,3 genes,Saleh-2013-Molecular architectu,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5318,PHI:3912,UniProt,Q04KT1,GenBank,ABJ55355,,,D39,Etrx2,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung; blood; nasopharynx,surface-exposed thioredoxin-family lipoprotein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; paraquat,"H2O2: CHEBI:16240; paraquat, : CHEBI:34905",,,,,gene mutation,,,RP,24136784,PubMed,10.1002/emmm.201202435,,xjuan@iqfr.csic.es,"both Etrx1 and Etrx2 can function as redox partners for SpMsrAB2 since the inactivation of both Etrx proteins or SpMsrAB2 renders pneumococci, to varying degrees, sensitive to extracellular peroxide stress.",M Saleh 2013,2013,3 genes,Saleh-2013-Molecular architectu,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5319,PHI:3913,UniProt,Q04LM6,GenBank,ABJ53896,,,D39,SpMsrAB2,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia; otitis media; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung; blood; nasopharynx,methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; paraquat,"H2O2: CHEBI:16240; paraquat, : CHEBI:34905",,,,,gene mutation,,,RP,24136784,PubMed,10.1002/emmm.201202435,,xjuan@iqfr.csic.es,"both Etrx1 and Etrx2 can function as redox partners for SpMsrAB2 since the inactivation of both Etrx proteins or SpMsrAB2 renders pneumococci, to varying degrees, sensitive to extracellular peroxide stress.",M Saleh 2013,2013,3 genes,Saleh-2013-Molecular architectu,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5320,PHI:3914,UniProt,Q0V515,GenBank,EAT92394,,,SN15,Sdh1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Stagonospora nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Grandin,,,leaf; seedling,encodes succinic semialdehyde dehydrogenase,,,,reduced virulence,,,,,seven dpi (half as pathogenic as wild type),increased,,wild type,,no,gamma-aminobutyric acid; H2O2,gamma-aminobutyric acid: CHEBI:16865; H2O2: CHEBI:16240,,,,,gene disruption; gene complementation,,,RP,24265684,PubMed,10.1371/journal.pone.0078368,,peter.solomon@anu.edu.au,Mutants strains grew poorly on gamma-aminobutyric acid as a nitrogen source. The sdh1 mutants were more susceptible to reactive oxygen stress but were less affected by increased growth temperatures.,O Mead 2013,2013,1 gene,Mead-2013-Characterising the R,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5321,PHI:3915,UniProt,Q02RX2,GenBank,ABJ13079,,,UCBPP-PA14,SuhB,,,,,,,287,Pseudomonas aeruginosa,1009714,PAK,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bronchoalveolar lavage fluid,an essential gene for the T3SS gene expression,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24169572,PubMed,10.1128/mBio.00419-13,,wuweihui@nankai.edu.cn,,K Li 2013,2013,1 gene,Li-2013-SuhB Is a Regulator,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5322,PHI:3916,UniProt,A0Q881,GenBank,ABK90446,,,U112,AnsP,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,amino acid transporter,,,,reduced virulence,,,,,,,,wild type,,no,asparagine; aspartic acid; ammonia,asparagine: CHEBI:22653; aspartic acid: CHEBI:22660; ammonia: CHEBI:16134,,,,,gene deletion; gene complementation,,,RP,24134488,PubMed,10.1111/cmi.12227,,alain.charbit@inserm.fr,The intracellular growth defect of the mutant was fully and specifically reversed by addition of asparagine or asparagine-containing dipeptides as well as by simultaneous addition of aspartic acid and ammonium.,G Gesbert 2013,2013,1 gene,Gesbert-2013-Asparagine assimilat,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5323,PHI:3917,UniProt,A0A0E0SGT0,EMBL,FGRAMPH1_01T24451,,,PH-1,FgMkk1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spike,encoding the putative MAPKK,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,congo red; calcofluor white; iprodione; fludioxonil; sorbitol; NaCl; paraquat; H2O2,"congo red: CHEBI:34653; calcofluor white: CHEBI:50011; iprodione: CHEBI:28909, CAS:36734-19-7; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; paraquat: CHEBI:34905; H2O2: CHEBI:16240",,,,,gene deletion; gene complementation,,,RP,24237706,PubMed,10.1111/1462-2920.12334,,zhma@zju.edu.cn,"Mutant exhibited increased sensitivity to osmotic stress generated by 1 M sorbitol and 0.7 M NaCl, and to oxidative stress mediated by 1 mM paraquat, but not by 0.2 mM H2O2 / revealed decreased sensitivity to the dicarboximide fungicide iprodione and the phenylpyrrole fungicide fludioxonil / increased sensitivity to CR and CFW",Y Yun 2013,2013,1 gene,Yun-2013-The MAPKK FgMkk1 of,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5324,PHI:3918,UniProt,A1A652,GenBank,DAA04933,,,521,fer2,chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,leaf,encoding a high-affinity iron permease,,,cAMP pathway,reduced virulence,,no,no,yes,,,,reduced,,no,,,,,,,gene deletion; gene complementation,,,RP,17138696,PubMed,10.1105/tpc.106.043588,,kahmann@staff.uni-marburg.de,"when grown on low-iron plates, fer2 mutants were reduced in growth com-pared with the wild type",H Eichhorn 2013,2013,2 genes,Eichhorn-2006-A ferroxidation_perm,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5325,PHI:3919,UniProt,Q4PIF8,GenBank,DAA04932,,,521,fer1,chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays,,,leaf,encoding an iron multicopper oxidase,,,cAMP pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,RP,17138696,PubMed,10.1105/tpc.106.043588,,kahmann@staff.uni-marburg.de,,H Eichhorn 2013,2013,2 genes,Eichhorn-2006-A ferroxidation_perm,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5326,PHI:3920,UniProt,Q88A90,GenBank,AAO54046,,,DC3000,HopF2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24237140,PubMed,10.1111/tpj.12381,,pinghe@tamu.edu,,J Zhou 2013,2013,1 gene,Zhou-2013-Pseudomonas syringae,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5327,PHI:3921,UniProt,M4WEN8,GenBank,AGI07391,,,Aw12879,LOV,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,photreceptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,RP,24260514,PubMed,10.1371/journal.pone.0080930,,orellano@ibr-conicet.gov.ar,,I Kraiselburd 2013,2013,1 gene,Kraiselburd-2013-The LOV Protein of X,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5328,PHI:3922,UniProt,N1NKQ7,GenBank,CCW30936,,,F1,FliZ,,,,,,,628,Xenorhabdus nematophila,1306162,F1,,moths,7109,Spodoptera littoralis (related: african cotton leafworm),,,,larva,global regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24204316,PubMed,10.1371/journal.pgen.1003915,,givaudan@un iv-montp2.fr,,G Jubelin 2013,2013,1 gene,Jubelin-2013-FliZ Is a Global Reg,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5329,PHI:3923,UniProt,Q50604,GenBank,AAK46150,,,CDC1551,cor,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver,carbon monoxide resistance gene,,,,reduced virulence,,,,,,,,,,no,plumbagin; NO; CO,plumbagin: CHEBI:8273; NO: CHEBI:16480; CO: CHEBI:17245,,,,,gene mutation; gene complementation,,,RP,24255121,PubMed,10.1128/mBio.00721-13,,michael.shiloh@utsouthwestern.edu,"Disruption of Rv1829 (carbon monoxide resistance, Cor) leads to marked CO sensitivity.",V M Zacharia 2013,2013,1 gene,"Zacharia-2013-cor, a Novel Carbon",Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5330,PHI:3924,UniProt,I1S2J9,BROAD,FGSG_10995,,,,FgABC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kadrilj,,,spikelet,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5331,PHI:3925,UniProt,I1RL06,BROAD,FGSG_04580,,,PH1,FgABC3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kadrilj,,,spikelet,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5332,PHI:3926,,no data found,BROAD,FGSG_17046,,,,FgABC2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kadrilj,,,spikelet,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5333,PHI:3927,,no data found,BROAD,FGSG_17058,,,,FgABC4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kadrilj,,,spikelet,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5334,PHI:3924,UniProt,I1S2J9,BROAD,FGSG_10995,,,,FgABC1,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kadrilj,,,spikelet,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5335,PHI:3925,UniProt,I1RL06,BROAD,FGSG_04580,,,PH1,FgABC3,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kadrilj,,,spikelet,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5336,PHI:3926,,no data found,BROAD,FGSG_17046,,,,FgABC2,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kadrilj,,,spikelet,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5337,PHI:3927,,no data found,BROAD,FGSG_17058,,,,FgABC4,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kadrilj,,,spikelet,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5338,PHI:3924,UniProt,I1S2J9,BROAD,FGSG_10995,,,,FgABC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),cv. Barke,,,spikelet,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5339,PHI:3925,UniProt,I1RL06,BROAD,FGSG_04580,,,PH1,FgABC3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),cv. Barke,,,spikelet,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5340,PHI:3926,,no data found,BROAD,FGSG_17046,,,,FgABC2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),cv. Barke,,,spikelet,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5341,PHI:3927,,no data found,BROAD,FGSG_17058,,,,FgABC4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),cv. Barke,,,spikelet,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5342,PHI:3924,UniProt,I1S2J9,BROAD,FGSG_10995,,,,FgABC1,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),cv. Barke,,,spikelet,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5343,PHI:3925,UniProt,I1RL06,BROAD,FGSG_04580,,,PH1,FgABC3,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),cv. Barke,,,spikelet,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5344,PHI:3926,,no data found,BROAD,FGSG_17046,,,,FgABC2,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),cv. Barke,,,spikelet,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5345,PHI:3927,,no data found,BROAD,FGSG_17058,,,,FgABC4,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),cv. Barke,,,spikelet,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5346,PHI:3924,UniProt,I1S2J9,BROAD,FGSG_10995,,,,FgABC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Jubilee,,,stem,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5347,PHI:3925,UniProt,I1RL06,BROAD,FGSG_04580,,,PH1,FgABC3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Jubilee,,,stem,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5348,PHI:3926,,no data found,BROAD,FGSG_17046,,,,FgABC2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Jubilee,,,stem,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5349,PHI:3927,,no data found,BROAD,FGSG_17058,,,,FgABC4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Jubilee,,,stem,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5350,PHI:3924,UniProt,I1S2J9,BROAD,FGSG_10995,,,,FgABC1,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Jubilee,,,stem,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5351,PHI:3925,UniProt,I1RL06,BROAD,FGSG_04580,,,PH1,FgABC3,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Jubilee,,,stem,ABC transporter,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5352,PHI:3926,,no data found,BROAD,FGSG_17046,,,,FgABC2,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Jubilee,,,stem,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5353,PHI:3927,,no data found,BROAD,FGSG_17058,,,,FgABC4,,,,,,,5518,Fusarium graminearum,,NRRL 13383,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Jubilee,,,stem,ABC transporter,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,tebuconazole; prothioconazole; epoxyconazole; fenarimol,,,,,,gene disruption,,,RP,24244413,PubMed,10.1371/journal.pone.0079042,,G A Ammar 2013,"Deletion of FgABC3 and FgABC4 belonging to group I of ABC-G and to group V of ABC-C subfamilies of ABC transporters, respectively, considerably increased the sensitivity to the class I sterol biosynthesis inhibitors triazoles and fenarimol.",,2013,4 genes,Abou Ammar-2013-Identification of AB,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5354,PHI:3928,UniProt,Q8ZQE4,GenBank,AAL19878,,,LT2,MacB,,,,,,PHI:3929,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,food poisoning; enteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,ABC-type efflux pump,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion,,,RP,24169575,PubMed,10.1128/mBio.00630-13,,handrews@medicine.tamhsc.edu,"macAB mutants appear to be unable to induce protection against exogenous H 2 O 2 in vitro , in contrast to the isogenic wild type",L M Bogomolnaya 2013,2013,2 genes,Bogomolnaya-2013-The ABC-Type Efflux,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5355,PHI:3929,UniProt,E8XCP9,GenBank,ADX1663,,,ST4/74,MacA,,,,,,PHI:3928,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,food poisoning; enteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,ABC-type efflux pump,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion,,,RP,24169575,PubMed,10.1128/mBio.00630-13,,handrews@medicine.tamhsc.edu,"macAB mutants appear to be unable to induce protection against exogenous H 2 O 2 in vitro , in contrast to the isogenic wild type",L M Bogomolnaya 2013,2013,2 genes,Bogomolnaya-2013-The ABC-Type Efflux,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5356,PHI:3930,UniProt,Q5J7N6,GenBank,AAS64313,,,,ChAP1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Jubilee,,,leaf,stress response factors,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; calcofluor white stain; menadione; MES hydrate; H2O2,H2O2: CHEBI:16240; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; menadione: CHEBI:28869; MES hydrate: CHEBI:39005,,,,,gene deletion,,,RP,24164316,PubMed,10.1111/1574-6968.12314,,horwitz@tx.technion.ac.il,"The double mutant is sensitive to oxidative andosmotic stresses, as well as to stressors that compromise cell wall integrity, but to the same extent as each single mutant, and there is no evidence for an additive effect on inhibition of growth.",S Shalaby 2013,2013,2 genes,Shalaby-2013-Genetic interaction,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5357,PHI:3931,UniProt,Q6SLC2,GenBank,AAR29904,,,C4,Skn7,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Jubilee,,,leaf,stress response factors,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; calcofluor white stain; menadione; MES hydrate; H2O2,H2O2: CHEBI:16240; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; menadione: CHEBI:28869; MES hydrate: CHEBI:39005,,,,,gene deletion,,,RP,24164316,PubMed,10.1111/1574-6968.12314,,horwitz@tx.technion.ac.il,"The double mutant is sensitive to oxidative andosmotic stresses, as well as to stressors that compromise cell wall integrity, but to the same extent as each single mutant, and there is no evidence for an additive effect on inhibition of growth.",S Shalaby 2013,2013,2 genes,Shalaby-2013-Genetic interaction,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5358,PHI:3930,UniProt,Q5J7N6,GenBank,AAS64313,,,,ChAP1,,,,,,PHI:3931,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Jubilee,,,leaf,stress response factors,,,,reduced virulence,,,,,,,,,,no,sorbitol; calcofluor white stain; menadione; MES hydrate; H2O2,H2O2: CHEBI:16240; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; menadione: CHEBI:28869; MES hydrate: CHEBI:39005,,,,,gene deletion,,,RP,24164316,PubMed,10.1111/1574-6968.12314,,horwitz@tx.technion.ac.il,"The double mutant is sensitive to oxidative andosmotic stresses, as well as to stressors that compromise cell wall integrity, but to the same extent as each single mutant, and there is no evidence for an additive effect on inhibition of growth.",S Shalaby 2013,2013,2 genes,Shalaby-2013-Genetic interaction,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5359,PHI:3931,UniProt,Q6SLC2,GenBank,AAR29904,,,C4,Skn7,,,,,,PHI:3930,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. Jubilee,,,leaf,stress response factors,,,,reduced virulence,,,,,,,,,,no,sorbitol; calcofluor white stain; menadione; MES hydrate; H2O2,H2O2: CHEBI:16240; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; menadione: CHEBI:28869; MES hydrate: CHEBI:39005,,,,,gene deletion,,,RP,24164316,PubMed,10.1111/1574-6968.12314,,horwitz@tx.technion.ac.il,"The double mutant is sensitive to oxidative andosmotic stresses, as well as to stressors that compromise cell wall integrity, but to the same extent as each single mutant, and there is no evidence for an additive effect on inhibition of growth.",S Shalaby 2013,2013,2 genes,Shalaby-2013-Genetic interaction,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5360,PHI:3932,UniProt,D1DDF4,GenBank,EEZ46324,,,FA19,LptA,,,,,,,485,Neisseria gonorrhoeae,242231,FA 1090,gonorrhea,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,vagina,phosphoethanolamine transferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24255126,PubMed,10.1128/mBio.00892-13,,mmhobbs@med.unc.edu,,M M Hobbs 2013,2013,1 gene,Hobbs-2013-Lipid A's Structure,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5361,PHI:3932,UniProt,D1DDF4,GenBank,EEZ46324,,,FA19,LptA,,,,,,,485,Neisseria gonorrhoeae,242231,FA 1090,gonorrhea,primates,9606,Homo sapiens (related: human),,,,reproductive system,phosphoethanolamine transferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24255126,PubMed,10.1128/mBio.00892-13,,mmhobbs@med.unc.edu,,M M Hobbs 2013,2013,1 gene,Hobbs-2013-Lipid A's Structure,Batch033,2013-12-01,,,,,,,,,,,,,,
,,Record 5362,PHI:3933,UniProt,C9W7X1,GenBank,ACN32207,,,,CgPKS1,,,,,,,31870,Colletotrichum graminicola,,CgM2,anthracnose (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Golden Jubilee,,,leaf,polyketide synthase,,,,loss of pathogenicity,,yes,yes,no,,,,aberrant,aberrant,no,nile red; calcofluor white,calcofluor white: CHEBI:50011; Nile red: CHEBI:52169,,,,,gene disruption; gene complementation,,,RP,24261846,PubMed,10.1094/MPMI-09-13-0267-R,,ralf.horbach@landw.unihalle.de,"Nonmelanized Cgpks1 appressoria were sensitive to externally applied cell wall""degrading enzymes whereas melanized appressoria were not affected",N Ludwig 2013,2013,1 gene,Horbach-2013-Melanin is not requi,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5363,PHI:3934,UniProt,B0BES0,GenBank,CAP12328,,,20.1,cpnox2,,,,,,,5111,Claviceps purpurea,1111077,Cp20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,spike,part of NADPH oxidase complex,,,,increased virulence (hypervirulence),,,,,,reduced,,,wild type,no,menadione,menadione: CHEBI:28869,,,,,gene deletion; gene complementation,,,RP,23777432,PubMed,10.1094/MPMI-03-13-0064-R,,tudzyns@uni-muenster.de,All tested deletion mutants already showed enhanced sensitivity to oxida-tive stress at low menadione concentrations,J Schürmann 2013,2013,2 gene,Schurmann-2013-Molecular characteri,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5364,PHI:3935,UniProt,M1W1U4,GenBank,CCE27055,,,20.1,cppls1,,,,,,,5111,Claviceps purpurea,1111077,Cp20.1,ergot,monocots,4550,Secale cereale (related: rye),,,,spike,part of NADPH oxidase complex,,,,reduced virulence,,,,,,wild type,,,wild type,no,menadione,menadione: CHEBI:28869,,,,,gene deletion; gene complementation,,,RP,23777432,PubMed,10.1094/MPMI-03-13-0064-R,,tudzyns@uni-muenster.de,All tested deletion mutants already showed enhanced sensitivity to oxida-tive stress at low menadione concentrations,J Schürmann 2013,2013,2 gene,Schurmann-2013-Molecular characteri,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5365,PHI:3936,UniProt,A7EB00,GenBank,EDN99628,,,1980 UF-70,Ss-caf1,chromosome 4,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold; stem rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,encodes a secretory protein with a putative Ca2+ binding EF-hand motif,,,,loss of pathogenicity,,yes,yes,no,,,,reduced,,no,ca2+; NaCl; KCl; MgCl2; sorbitol; mannitol; sucrose; G418,ca2+: CHEBI:29108; NaCl: CHEBI:26710; KCl: CHEBI:32588; MgCl2: CHEBI:6636; sorbitol: CHEBI:17924; mannitol: CHEBI:29864; sucrose: CHEBI:17992,,,,,gene disruption; gene complementation,,,RP,24299212,PubMed,10.1094/MPMI-05-13-0145-R,,yanpingfu@mail.hzau.edu.cn,mutant Sunf-MT6 is more severely inhibited by a broad range of stress conditions than the wild type,X Xiao 2014,2014,1 gene,Xiao-2014-Novel Secretory Prot,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5366,PHI:3936,UniProt,A7EB00,GenBank,EDN99628,,,1980 UF-70,Ss-caf1,chromosome 4,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold; stem rot,eudicots,3708,Brassica napus (related: rape),,,,leaf,encodes a secretory protein with a putative Ca2+ binding EF-hand motif,,,,loss of pathogenicity,,yes,yes,no,,,,reduced,,no,ca2+; NaCl; KCl; MgCl2; sorbitol; mannitol; sucrose; G418,ca2+: CHEBI:29108; NaCl: CHEBI:26710; KCl: CHEBI:32588; MgCl2: CHEBI:6636; sorbitol: CHEBI:17924; mannitol: CHEBI:29864; sucrose: CHEBI:17992,,,,,gene disruption; gene complementation,,,RP,24299212,PubMed,10.1094/MPMI-05-13-0145-R,,yanpingfu@mail.hzau.edu.cn,mutant Sunf-MT6 is more severely inhibited by a broad range of stress conditions than the wild type,X Xiao 2014,2014,1 gene,Xiao-2014-Novel Secretory Prot,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5367,PHI:3936,UniProt,A7EB00,GenBank,EDN99628,,,1980 UF-70,Ss-caf1,chromosome 4,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold; stem rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. chinensis (bok-choy),,,leaf,encodes a secretory protein with a putative Ca2+ binding EF-hand motif,,,,loss of pathogenicity,,yes,yes,no,,,,reduced,,no,ca2+; NaCl; KCl; MgCl2; sorbitol; mannitol; sucrose; G418,ca2+: CHEBI:29108; NaCl: CHEBI:26710; KCl: CHEBI:32588; MgCl2: CHEBI:6636; sorbitol: CHEBI:17924; mannitol: CHEBI:29864; sucrose: CHEBI:17992,,,,,gene disruption; gene complementation,,,RP,24299212,PubMed,10.1094/MPMI-05-13-0145-R,,yanpingfu@mail.hzau.edu.cn,mutant Sunf-MT6 is more severely inhibited by a broad range of stress conditions than the wild type,X Xiao 2014,2014,1 gene,Xiao-2014-Novel Secretory Prot,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5368,PHI:3936,UniProt,A7EB00,GenBank,EDN99628,,,1980 UF-70,Ss-caf1,chromosome 4,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold; stem rot,eudicots,4073,Capsicum frutescens (related: hot pepper),,,,leaf,encodes a secretory protein with a putative Ca2+ binding EF-hand motif,,,,loss of pathogenicity,,yes,yes,no,,,,reduced,,no,ca2+; NaCl; KCl; MgCl2; sorbitol; mannitol; sucrose; G418,ca2+: CHEBI:29108; NaCl: CHEBI:26710; KCl: CHEBI:32588; MgCl2: CHEBI:6636; sorbitol: CHEBI:17924; mannitol: CHEBI:29864; sucrose: CHEBI:17992,,,,,gene disruption; gene complementation,,,RP,24299212,PubMed,10.1094/MPMI-05-13-0145-R,,yanpingfu@mail.hzau.edu.cn,mutant Sunf-MT6 is more severely inhibited by a broad range of stress conditions than the wild type,X Xiao 2014,2014,1 gene,Xiao-2014-Novel Secretory Prot,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5369,PHI:3936,UniProt,A7EB00,GenBank,EDN99628,,,1980 UF-70,Ss-caf1,chromosome 4,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold; stem rot,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,encodes a secretory protein with a putative Ca2+ binding EF-hand motif,,,,loss of pathogenicity,,yes,yes,no,,,,reduced,,no,ca2+; NaCl; KCl; MgCl2; sorbitol; mannitol; sucrose; G418,ca2+: CHEBI:29108; NaCl: CHEBI:26710; KCl: CHEBI:32588; MgCl2: CHEBI:6636; sorbitol: CHEBI:17924; mannitol: CHEBI:29864; sucrose: CHEBI:17992,,,,,gene disruption; gene complementation,,,RP,24299212,PubMed,10.1094/MPMI-05-13-0145-R,,yanpingfu@mail.hzau.edu.cn,mutant Sunf-MT6 is more severely inhibited by a broad range of stress conditions than the wild type,X Xiao 2014,2014,1 gene,Xiao-2014-Novel Secretory Prot,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5370,PHI:3936,UniProt,A7EB00,GenBank,EDN99628,,,1980 UF-70,Ss-caf1,chromosome 4,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold; stem rot,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,encodes a secretory protein with a putative Ca2+ binding EF-hand motif,,,,loss of pathogenicity,,yes,yes,no,,,,reduced,,no,ca2+; NaCl; KCl; MgCl2; sorbitol; mannitol; sucrose; G418,ca2+: CHEBI:29108; NaCl: CHEBI:26710; KCl: CHEBI:32588; MgCl2: CHEBI:6636; sorbitol: CHEBI:17924; mannitol: CHEBI:29864; sucrose: CHEBI:17992,,,,,gene disruption; gene complementation,,,RP,24299212,PubMed,10.1094/MPMI-05-13-0145-R,,yanpingfu@mail.hzau.edu.cn,mutant Sunf-MT6 is more severely inhibited by a broad range of stress conditions than the wild type,X Xiao 2014,2014,1 gene,Xiao-2014-Novel Secretory Prot,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5371,PHI:3936,UniProt,A7EB00,GenBank,EDN99628,,,1980 UF-70,Ss-caf1,chromosome 4,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold; stem rot,eudicots,3847,Glycine max (related: soybean),,,,leaf,encodes a secretory protein with a putative Ca2+ binding EF-hand motif,,,,loss of pathogenicity,,yes,yes,no,,,,reduced,,no,ca2+; NaCl; KCl; MgCl2; sorbitol; mannitol; sucrose; G418,ca2+: CHEBI:29108; NaCl: CHEBI:26710; KCl: CHEBI:32588; MgCl2: CHEBI:6636; sorbitol: CHEBI:17924; mannitol: CHEBI:29864; sucrose: CHEBI:17992,,,,,gene disruption; gene complementation,,,RP,24299212,PubMed,10.1094/MPMI-05-13-0145-R,,yanpingfu@mail.hzau.edu.cn,mutant Sunf-MT6 is more severely inhibited by a broad range of stress conditions than the wild type,X Xiao 2014,2014,1 gene,Xiao-2014-Novel Secretory Prot,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5372,PHI:3937,UniProt,D2UB90,GenBank,CBA15086,,,GPE PC73,OmpA1,,,,,,,29447,Xanthomonas albilineans,,XaFL07-1,leaf scald,monocots,4547,Saccharum officinarum (related: sugarcane),cv. CP68-1026,,,stem; leaf,putative ompa family outer membrane protein precursor,,,,reduced virulence,,,,yes,,,,,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation: characterised; gene complementation,,,RP,23758144,PubMed,10.1094/MPMI-01-13-0002-R,,dgabr@ufl.edu,mutants showed impaired resistance to sodium dodecyl sulfate (SDS),L A Fleites 2013,2013,1 gene,Fleites-2013-Xanthomonas albiline,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5373,PHI:3938,,no data found,,,,,,CRN20_624,,,,,,,4784,Phytophthora capsici,,,Phytophthora blight,eudicots,4100,Nicotiana benthamiana (no common name found),H2B-RFP,,,leaf,CRN effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24155749,PubMed,10.3389/fpls.2013.00387,,e.huitema@dundee.ac.uk,Agrobacterium tumefaciens strain AGL1 was used as recipient strain for all constructs,R Stam 2013,2013,3 genes,Stam-2013-Characterization of,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5374,PHI:3939,,no data found,,,,,,CRN83_152,,,,,,,4784,Phytophthora capsici,,,Phytophthora blight,eudicots,4100,Nicotiana benthamiana (no common name found),H2B-RFP,,,leaf,CRN effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24155749,PubMed,10.3389/fpls.2013.00387,,e.huitema@dundee.ac.uk,Agrobacterium tumefaciens strain AGL1 was used as recipient strain for all constructs,R Stam 2013,2013,3 genes,Stam-2013-Characterization of,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5375,PHI:3940,,no data found,,,,,,CRN79_188,,,,,,,4784,Phytophthora capsici,,,Phytophthora blight,eudicots,4100,Nicotiana benthamiana (no common name found),H2B-RFP,,,leaf,CRN effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24155749,PubMed,10.3389/fpls.2013.00387,,e.huitema@dundee.ac.uk,Agrobacterium tumefaciens strain AGL1 was used as recipient strain for all constructs,R Stam 2013,2013,3 genes,Stam-2013-Characterization of,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5376,PHI:3938,,no data found,,,,,,CRN20_624,,,,,,,4784,Phytophthora capsici,,,Phytophthora blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),H2B-RFP,,,leaf,CRN effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24155749,PubMed,10.3389/fpls.2013.00387,,e.huitema@dundee.ac.uk,Agrobacterium tumefaciens strain AGL1 was used as recipient strain for all constructs,R Stam 2013,2013,3 genes,Stam-2013-Characterization of,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5377,PHI:3939,,no data found,,,,,,CRN83_152,,,,,,,4784,Phytophthora capsici,,,Phytophthora blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),H2B-RFP,,,leaf,CRN effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24155749,PubMed,10.3389/fpls.2013.00387,,e.huitema@dundee.ac.uk,Agrobacterium tumefaciens strain AGL1 was used as recipient strain for all constructs,R Stam 2013,2013,3 genes,Stam-2013-Characterization of,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5378,PHI:3940,,no data found,,,,,,CRN79_188,,,,,,,4784,Phytophthora capsici,,,Phytophthora blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),H2B-RFP,,,leaf,CRN effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24155749,PubMed,10.3389/fpls.2013.00387,,e.huitema@dundee.ac.uk,Agrobacterium tumefaciens strain AGL1 was used as recipient strain for all constructs,R Stam 2013,2013,3 genes,Stam-2013-Characterization of,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5379,PHI:3941,UniProt,Q4UZG1,GenBank,AAY47562,,,8004,XC_0481,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,anthranilate synthase component II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5380,PHI:3942,UniProt,Q4UZD3,GenBank,AAY47590,,,8004,XC_0509,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,phosphoribosylamine-glycine ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5381,PHI:3943,UniProt,Q4UY20,GenBank,AAY48053,,,8004,XC_0979,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,fructose-bisphosphate aldolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5382,PHI:3944,UniProt,Q4UVI4,GenBank,AAY48939,,,8004,XC_1876,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,argininosuccinate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5383,PHI:3945,UniProt,Q4UUL4,GenBank,AAY49259,,,8004,XC_2203,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,nucleotide diphosphate kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5384,PHI:3946,UniProt,Q4UYV4,GenBank,AAY47769,,,8004,XC_0690,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,"sugar kinase, adenosine kinase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5385,PHI:3947,UniProt,Q4V006,GenBank,AAY47367,,,8004,XC_0281,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,oxidoreductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5386,PHI:3948,UniProt,Q4UZJ1,GenBank,AAY47532,,,8004,XC_0450,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,4-hydroxyphenylpyruvate deoxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5387,PHI:3949,UniProt,Q4UYZ3,GenBank,AAY47730,,,8004,XC_0650,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,"hypothetical protein, outer membrane beta-barrel",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5388,PHI:3950,UniProt,Q4UYA7,GenBank,AAY47966,,,8004,XC_0892,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,glutamate-1-semialdehyde aminotransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5389,PHI:3951,UniProt,Q4UWY6,GenBank,AAY48437,,,8004,XC_1368,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,"osmotically inducible protein, oxidative stress resistance",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5390,PHI:3952,UniProt,Q4UWJ5,GenBank,AAY48578,,,8004,XC_1510,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,"TldD protein, DNA gyrase control?",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5391,PHI:3953,UniProt,Q4UU61,GenBank,AAY49412,,,8004,XC_2359,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,elongation factor P,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5392,PHI:3954,UniProt,Q4URJ2,GenBank,AAY50331,,,8004,XC_3287,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,phosphoglycerate mutase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5393,PHI:3955,UniProt,Q4URA5,GenBank,AAY50418,,,8004,XC_3374,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,asparaginase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5394,PHI:3956,UniProt,Q4UR27,GenBank,AAY50496,,,8004,XC_3452,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,two-component regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5395,PHI:3957,UniProt,Q4UQL6,GenBank,AAY50657,,,8004,XC_3615,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,electron transfer flavoprotein alpha subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5396,PHI:3958,UniProt,Q4UZL6,GenBank,AAY47507,,,8004,XC_0423,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,maltooligosyltrehalose trehalohydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5397,PHI:3959,UniProt,Q4UZE1,GenBank,AAY47582,,,8004,XC_0501,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,NADH pyrophosphatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5398,PHI:3960,UniProt,Q4UZA5,GenBank,AAY47618,,,8004,XC_0537,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,ATP-dependant DNA helicase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5399,PHI:3961,UniProt,Q4UZ72,GenBank,AAY47651,,,8004,XC_0570,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,iron utilisation protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5400,PHI:3962,UniProt,Q4UZ13,GenBank,AAY47710,,,8004,XC_0630,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,hypothetical protein with AIM24 domain,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5401,PHI:3963,UniProt,Q4UYZ7,GenBank,AAY47726,,,8004,XC_0646,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,carboxyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5402,PHI:3964,UniProt,Q4UXH1,GenBank,AAY48252,,,8004,XC_1182,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,glutathione synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5403,PHI:3965,UniProt,Q4UWM4,GenBank,AAY48549,,,8004,XC_1481,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5404,PHI:3966,UniProt,Q4UWE2,GenBank,AAY48631,,,8004,XC_1565,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,N-5-glutamine S-adenosyl-L-methionine-dependent methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5405,PHI:3967,UniProt,Q4UUQ5,GenBank,AAY49218,,,8004,XC_2162,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,hypothetical protein with peptidase M14 domain,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5406,PHI:3968,UniProt,Q4UTV7,GenBank,AAY49516,,,8004,XC_2466,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,aspartate alpha-decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23819805,PubMed,10.1094/MPMI-05-13-0155-R,,m.dow@ucc.ie,,A O'Connell 2013,2013,28 genes,O'Connell-2013-Proteomics analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5407,PHI:3969,,no data found,,,,,,BLG01,chromosome 9,,,,,,4779,Bremia lactucae,,,downy mildew,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,GKLR effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23883357,PubMed,10.1094/MPMI-05-13-0142-R,,g.vandenackerveken@uu.nl,Clones were electrotransformed into Agrobacterium tumefaciens C58C1 (pGV2260),J H M Stassen 2013,2013,2 genes,Stassen-2013-Specific in planta r,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5408,PHI:3970,,no data found,,,,,,BLG03,chromosome 2,,,,,,4779,Bremia lactucae,,,downy mildew,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,GKLR effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23883357,PubMed,10.1094/MPMI-05-13-0142-R,,g.vandenackerveken@uu.nl,Clones were electrotransformed into Agrobacterium tumefaciens C58C1 (pGV2260),J H M Stassen 2013,2013,2 genes,Stassen-2013-Specific in planta r,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5409,PHI:3971,UniProt,X4QM59,,,,,,Bdtf1,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,detoxifying brassinin and maintaining virulence,,,,unaffected pathogenicity,,no,no,no,,wild type,,wild type,wild type,no,brassinin,brassinin: CHEBI:38119,,,,,gene deletion,,,RP,23945003,PubMed,10.1094/MPMI-07-13-0186-R,,yangrae@hawaii.edu,,A Srivastava 2013,2013,1 gene,Srivastava-2013-The Bdtf1 gene in Al,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5410,PHI:3971,UniProt,X4QM59,,,,,,Bdtf1,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,detoxifying brassinin and maintaining virulence,,,,reduced virulence,,no,no,no,,wild type,,wild type,wild type,no,brassinin,brassinin: CHEBI:38119,,,,,gene deletion; gene complementation,,,RP,23945003,PubMed,10.1094/MPMI-07-13-0186-R,,yangrae@hawaii.edu,"When grown in a medium containing 100 M brassinin, wild-type mycelium entirely converted the brassinin into a nontoxic derivative, of which the precise chemical nature was not established. Mutants of the Bdtf1 gene were unable to perform this conversion.",A Srivastava 2013,2013,1 gene,Srivastava-2013-The Bdtf1 gene in Al,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5411,PHI:3971,UniProt,X4QM59,,,,,,Bdtf1,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. botrytis (cauliflower),,,leaf,detoxifying brassinin and maintaining virulence,,,,reduced virulence,,no,no,no,,wild type,,wild type,wild type,no,brassinin,brassinin: CHEBI:38119,,,,,gene deletion; gene complementation,,,RP,23945003,PubMed,10.1094/MPMI-07-13-0186-R,,yangrae@hawaii.edu,"When grown in a medium containing 100 M brassinin, wild-type mycelium entirely converted the brassinin into a nontoxic derivative, of which the precise chemical nature was not established. Mutants of the Bdtf1 gene were unable to perform this conversion.",A Srivastava 2013,2013,1 gene,Srivastava-2013-The Bdtf1 gene in Al,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5412,PHI:3971,UniProt,X4QM59,,,,,,Bdtf1,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. italica (sprouting broccoli),,,leaf,detoxifying brassinin and maintaining virulence,,,,reduced virulence,,no,no,no,,wild type,,wild type,wild type,no,brassinin,brassinin: CHEBI:38119,,,,,gene deletion; gene complementation,,,RP,23945003,PubMed,10.1094/MPMI-07-13-0186-R,,yangrae@hawaii.edu,"When grown in a medium containing 100 M brassinin, wild-type mycelium entirely converted the brassinin into a nontoxic derivative, of which the precise chemical nature was not established. Mutants of the Bdtf1 gene were unable to perform this conversion.",A Srivastava 2013,2013,1 gene,Srivastava-2013-The Bdtf1 gene in Al,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5413,PHI:3971,UniProt,X4QM59,,,,,,Bdtf1,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3711,Brassica rapa (related: field mustard),subsp. chinensis (bok-choy),,,leaf,detoxifying brassinin and maintaining virulence,,,,reduced virulence,,no,no,no,,wild type,,wild type,wild type,no,brassinin,brassinin: CHEBI:38119,,,,,gene deletion; gene complementation,,,RP,23945003,PubMed,10.1094/MPMI-07-13-0186-R,,yangrae@hawaii.edu,"When grown in a medium containing 100 M brassinin, wild-type mycelium entirely converted the brassinin into a nontoxic derivative, of which the precise chemical nature was not established. Mutants of the Bdtf1 gene were unable to perform this conversion.",A Srivastava 2013,2013,1 gene,Srivastava-2013-The Bdtf1 gene in Al,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5414,PHI:3971,UniProt,X4QM59,,,,,,Bdtf1,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3707,Brassica juncea (related: brown mustard),,,,leaf,detoxifying brassinin and maintaining virulence,,,,reduced virulence,,no,no,no,,wild type,,wild type,wild type,no,brassinin,brassinin: CHEBI:38119,,,,,gene deletion; gene complementation,,,RP,23945003,PubMed,10.1094/MPMI-07-13-0186-R,,yangrae@hawaii.edu,"When grown in a medium containing 100 M brassinin, wild-type mycelium entirely converted the brassinin into a nontoxic derivative, of which the precise chemical nature was not established. Mutants of the Bdtf1 gene were unable to perform this conversion.",A Srivastava 2013,2013,1 gene,Srivastava-2013-The Bdtf1 gene in Al,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5415,PHI:3972,UniProt,L2FHG9,GenBank,ELA25183,,,Nara gc5,CDA,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,anthracnose,flowering plants,3435,Persea americana (related: avocado),cv. Fuerte,,,fruit,chitin deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,RP,23902260,PubMed,10.1094/MPMI-03-13-0080-R,,noamal@agri.gov.il,,N Alkan 2013,2013,2 genes,Alkan-2013-Global aspects of pa,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5416,PHI:3973,UniProt,L2G011,GenBank,ELA3171,,,Nara gc5,ASP,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,anthracnose,flowering plants,3435,Persea americana (related: avocado),cv. Fuerte,,,fruit,aspartic protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,RP,23902260,PubMed,10.1094/MPMI-03-13-0080-R,,noamal@agri.gov.il,,N Alkan 2013,2013,2 genes,Alkan-2013-Global aspects of pa,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5417,PHI:3974,UniProt,T2FFS6,GenBank,AGV80544,,,,CpHsp24,,,,,,,5116,Cryphonectria parasitica,660469,EP155/2,blight (chestnut),eudicots,134033,Castanea dentata (related: american chestnut),,,,bark,heat shock protein,,,,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,24024764,PubMed,10.1094/MPMI-08-13-0225-R,,dhkim@chonbuk.ac.kr,"The mutants growth is susceptible to both heat and cold, though not to oxidative and osmotic stress",J Baek 2014,2014,1 gene,Baek-2014-Functional Analysis,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5418,PHI:3975,UniProt,G4MMK2,GenBank,EHA56980,,,70-15,MoIlv2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,acetolactate synthases,,,amino acid synthesis pathways,loss of pathogenicity,,yes,yes,,,reduced,,reduced,,no,valine; leucine; isoleucine,valine: CHEBI:27266; leucine: CHEBI:25017; isoleucine: CHEBI:24898,,,,,gene disruption; gene complementation,,,RP,23782532,PubMed,10.1111/mpp.12053,,zhgzhang@njau.edu.cn,"Exogenous amino acids partly restore conidial formation, appressorium formation and pathogenicity to the Moilv2 and Moilv6 mutants.",Y Du 2013,2013,2 genes,Du-2013-Acetolactate synthas,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5419,PHI:3976,UniProt,G4NC97,GenBank,EHA48246,,,70-15,MoIlv6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,acetolactate synthases,,,amino acid synthesis pathways,loss of pathogenicity,,yes,yes,,,reduced,,reduced,,no,valine; leucine; isoleucine,valine: CHEBI:27266; leucine: CHEBI:25017; isoleucine: CHEBI:24898,,,,,gene disruption; gene complementation,,,RP,23782532,PubMed,10.1111/mpp.12053,,zhgzhang@njau.edu.cn,"Exogenous amino acids partly restore conidial formation, appressorium formation and pathogenicity to the Moilv2 and Moilv6 mutants.",Y Du 2013,2013,2 genes,Du-2013-Acetolactate synthas,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5420,PHI:3975,UniProt,G4MMK2,GenBank,EHA56980,,,70-15,MoIlv2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,acetolactate synthases,,,amino acid synthesis pathways,loss of pathogenicity,,yes,yes,,,reduced,,reduced,,no,valine; leucine; isoleucine,valine: CHEBI:27266; leucine: CHEBI:25017; isoleucine: CHEBI:24898,,,,,gene disruption; gene complementation,,,RP,23782532,PubMed,10.1111/mpp.12053,,zhgzhang@njau.edu.cn,"Exogenous amino acids partly restore conidial formation, appressorium formation and pathogenicity to the Moilv2 and Moilv6 mutants.",Y Du 2013,2013,2 genes,Du-2013-Acetolactate synthas,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5421,PHI:3976,UniProt,G4NC97,GenBank,EHA48246,,,70-15,MoIlv6,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,acetolactate synthases,,,amino acid synthesis pathways,loss of pathogenicity,,yes,yes,,,reduced,,reduced,,no,valine; leucine; isoleucine,valine: CHEBI:27266; leucine: CHEBI:25017; isoleucine: CHEBI:24898,,,,,gene disruption; gene complementation,,,RP,23782532,PubMed,10.1111/mpp.12053,,zhgzhang@njau.edu.cn,"Exogenous amino acids partly restore conidial formation, appressorium formation and pathogenicity to the Moilv2 and Moilv6 mutants.",Y Du 2013,2013,2 genes,Du-2013-Acetolactate synthas,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5422,PHI:3977,UniProt,C9WMG8,GenBank,ACN69116,,,,Six6,chromosome 14,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain 007,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. C32,,,seedling,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24313955,PubMed,10.1094/MPMI-11-13-0330-R,,f.l.w.takken@uva.nl,,F Gawehns 2013,2013,1 gene,Gawehns-2013-The Fusarium oxyspor,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5423,PHI:3978,UniProt,Q0PZG3,GenBank,ABG57145,,,SSU,vasH,,,,,,,644,Aeromonas hydrophila,1073377,SSU,intestinal infection; extraintestinal infection,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,T6SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,18037263,PubMed,10.1016/j.micpath.2007.10.005,,achopra@utmb.edu,,G Suarez 2008,2008,2 genes,Suarez-2008-Molecular characteri,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5424,PHI:3979,UniProt,Q0PZG0,GenBank,ABG57148,,,SSU,vasK,,,,,,,644,Aeromonas hydrophila,1073377,SSU,intestinal infection; extraintestinal infection,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,T6SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,18037263,PubMed,10.1016/j.micpath.2007.10.005,,achopra@utmb.edu,,G Suarez 2008,2008,2 genes,Suarez-2008-Molecular characteri,Batch034,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5425,PHI:3980,UniProt,O84137,GenBank,AAC67726,,,D/UW-3/CX,CT135,,,,,,,813,Chlamydia trachomatis,272561,D/UW-3/CX,intestinal infection; extraintestinal infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,vagina; uterine cervix,virulence factors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24376189,PubMed,10.1111/2049-632X.12121,,hcaldwell@niaid.nih.gov,The plasmid and CT135 play distinct roles in the kinetics of infection and a strain possessing both genetic deficiencies is highly attenuated,G L Sturdevant 2013,2013,1 gene,Sturdevant-2013-Infectivity of uroge,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5426,PHI:3981,UniProt,Q99YP4,GenBank,AAK34382,,,M1 GAS,RocA,,,,,,,36470,Streptococcus sp. 'group A',36470,serotype M18,pharyngitis; toxic shock syndrome; sepsis,rodents,10090,Mus musculus (related: house mouse),FVB/N,,,nasopharynx,metabolic regulator with activity beyond the CovR/S regulon,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24367267,PubMed,10.1371/journal.ppat.1003842,,s.sriskandan@imperial.ac.uk,"RocA, underlies serotype M18 hyper-encapsulation",N N Lynskey 2013,2013,1 gene,Lynskey-2013-RocA Truncation Unde,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5427,PHI:3982,UniProt,Q2FV99,GenBank,AF162687_1,,,8325-4,SrtA,,,,,,,1280,Staphylococcus aureus,,Newman D2C,mastitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,mammary gland,"transpeptidase, anchors surface proteins with an LPXTG-motif sorting signal to the cell envelope",,,NF-kappaB; MAPK,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24330077,PubMed,10.1111/1574-6968.12354,,bo_liu@med.unc.edu,,F Chen 2013,2013,1 gene,Chen-2013-Role of Sortase A in,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5428,PHI:3983,UniProt,A0A0E0RU90,EMBL,FGRAMPH1_01T06021,,,,FGSG_02509.3 (Sc gpi7),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,glycosylphosphatidylinositol-anchored proteins,,,,reduced virulence,,,,yes,,aberrant,,reduced,wild type,no,congo red; calcofluor white; H2O2; menadione,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion; gene complementation,,,RP,24312325,PubMed,10.1371/journal.pone.0081603,,sharris2@unl.edu,"deltagpi7 mutants displayed increased sensitivity to calcofluor white, but not Congo red",W R Rittenour 2013,2013,3 genes,Rittenour-2013-Glycosylphosphatidyl,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5429,PHI:3984,UniProt,I1RD96,BROAD,FGSG_01588,,,,FGSG_01588 (Sc gpi7),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,glycosylphosphatidylinositol-anchored proteins,,,,unaffected pathogenicity,,,,no,,wild type,,wild type,wild type,no,congo red; calcofluor white; H2O2; menadione,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion,,,RP,24312325,PubMed,10.1371/journal.pone.0081603,,sharris2@unl.edu,not sensitive to any stresses; same phenotype as wild type,W R Rittenour 2013,2013,3 genes,Rittenour-2013-Glycosylphosphatidyl,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5430,PHI:3985,UniProt,I1RX03,BROAD,FGSG_08844,,,,FGSG_08844 (Sc gpi7),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,glycosylphosphatidylinositol-anchored proteins,,,,unaffected pathogenicity,,,,no,,wild type,,wild type,wild type,no,congo red; calcofluor white; H2O2; menadione,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion,,,RP,24312325,PubMed,10.1371/journal.pone.0081603,,sharris2@unl.edu,not sensitive to any stresses; same phenotype as wild type,W R Rittenour 2013,2013,3 genes,Rittenour-2013-Glycosylphosphatidyl,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5431,PHI:3986,UniProt,Q30H72,GenBank,AAY89396,,,NT-8,Bwc2,,,,,,,552467,Cryptococcus bacillisporus,294750,R265,pulmonary cryptococcosis; basal meningitis; cerebral cryptococcomas,rodents,10090,Mus musculus (related: house mouse),A/J,,,brain; lung; spleen,a light-dependent transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,23670558,PubMed,10.1128/IAI.00018-13,,idnurma@umkc.edu,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,P Zhu 2013,2013,1 gene,Zhu-2013-Congenic strains for,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5432,PHI:3987,UniProt,O93876,GenBank,AAD02822,,,155,cpkk1,,,,,,,5116,Cryphonectria parasitica,,Δcpku80,blight (chestnut),eudicots,134033,Castanea dentata (related: american chestnut),,,,stem,acts in a phosphorylation cascade essential for cell integrity,,,MAP2K,reduced virulence,yes,,,,,reduced,,reduced; aberrant,,no,sorbitol; NaCl; menadione; H2O2; sodium dodecyl sulphate (SDS); calcofluor white; Congo red; benomyl; hygromycin B; G418; fludioxonil,"congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; sodium dodecyl sulphate (SDS): CHEBI:8984; benomyl: CHEBI:3015, CAS:17804-35-2; hygromycin B: CHEBI:16976",,,,,gene deletion; gene complementation,,,RP,24373159,PubMed,10.1111/mpp.12111,,m.turina@ivv.cnr.it,"Sensitivity to menadione was observed in the deltacpkk1 and deltacpkk2 strains, while absence of growth was detected for deltacpkk1 in the presence of SDS / Hydrogen peroxide proved extremely toxic for the cpkk1 null mutant, since no growth was recorded; under the same conditions, growth of the deltacpkk2 strain was also strongly reduced / deltacpkk1 in both CR and CW, whereas specific inhibition of deltacpkk2 was only present in Calcofluor white containing media",M Moretti 2013,2013,3 genes,Moretti-2013-Functional character,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5433,PHI:3988,UniProt,Q6GX81,GenBank,AAT48729,,,EP67,cpkk2,,,,,,,5116,Cryphonectria parasitica,,Δcpku80,blight (chestnut),eudicots,134033,Castanea dentata (related: american chestnut),,,,stem,involved in the pheromone response pathway,,,MAP2K,reduced virulence,yes,,,,,reduced,,reduced; aberrant,,no,sorbitol; NaCl; menadione; H2O2; sodium dodecyl sulphate (SDS); calcofluor white; Congo red; benomyl; hygromycin B; G418; fludioxonil,"congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; sodium dodecyl sulphate (SDS): CHEBI:8984; benomyl: CHEBI:3015, CAS:17804-35-2; hygromycin B: CHEBI:16976",,,,,gene deletion; gene complementation,,,RP,24373159,PubMed,10.1111/mpp.12111,,m.turina@ivv.cnr.it,"Sensitivity to menadione was observed in the deltacpkk1 and deltacpkk2 strains, while absence of growth was detected for deltacpkk1 in the presence of SDS / Hydrogen peroxide proved extremely toxic for the cpkk1-null mutant, since no growth was recorded; under the same conditions, growth of the deltacpkk2 strain was also strongly reduced / deltacpkk1 in both CR and CW, whereas specific inhibition of deltacpkk2 was only present in Calcofluor white containing media",M Moretti 2013,2013,3 genes,Moretti-2013-Functional character,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5434,PHI:3989,UniProt,B2ZAW3,GenBank,ACC86141,,,EP67,cpkk3,,,,,,,5116,Cryphonectria parasitica,,Δcpku80,blight (chestnut),eudicots,134033,Castanea dentata (related: american chestnut),,,,stem,activated during high osmolarity response,,,MAP2K,unaffected pathogenicity,no,,,,,wild type,,wild type,,no,sorbitol; NaCl; menadione; H2O2; sodium dodecyl sulphate (SDS); calcofluor white; Congo red; benomyl; hygromycin B; G418; fludioxonil,"congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; sodium dodecyl sulphate (SDS): CHEBI:8984; benomyl: CHEBI:3015, CAS:17804-35-2; Hygromycin B: CHEBI:16976",,,,,gene deletion; gene complementation,,,RP,24373159,PubMed,10.1111/mpp.12111,,m.turina@ivv.cnr.it,No alterations were reported in deltacpkk3 except under hyperosmotic conditions and in presence of fludioxonil,M Moretti 2013,2013,3 genes,Moretti-2013-Functional character,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5435,PHI:3990,UniProt,Q66SY0,GenBank,AAU10633,,,,PKS12,,,,,,,5518,Fusarium graminearum,,SCK04,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),,,,spikelet,putative polyketide synthase; aurofusarin biosynthesis,,,,unaffected pathogenicity,,,,,,wild type,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,15811992,PubMed,10.1128/AEM.71.4.1701-1708.2005,,lee2443@snu.ac.kr,Targeted gene deletion and complementation analyses confirmed that both Gip1 and PKS12 are required for aurofusarin production in G. zeae,J Kim 2005,2005,2 genes,M1021Kim_AppEnvMicro2005_laccaseGzeae,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5436,PHI:3991,UniProt,I1RF62,GenBank,XM_382504,,,Ph-1,Gip1,chromosome 1,,,,,,5518,Fusarium graminearum,,SCK04,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),,,,spikelet,laccase; aurofusarin biosynthesis,,,,unaffected pathogenicity,,,,,,wild type,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,15811992,PubMed,10.1128/AEM.71.4.1701-1708.2005,,lee2443@snu.ac.kr,Targeted gene deletion and complementation analyses confirmed that both Gip1 and PKS12 are required for aurofusarin production in G. zeae,J Kim 2005,2005,2 genes,M1021Kim_AppEnvMicro2005_laccaseGzeae,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5437,PHI:3992,UniProt,J4W5V1,GenBank,EJP65725,,,ARSEF 2860,BbcreA,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,carbon catabolite repressor transcription factor homologue,,,,reduced virulence,,no,no,,,reduced,,reduced,,no,calcofluor white; Congo red; KCl; sorbitol; sodium dodecyl sulphate,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CAS:573-58-0; sorbitol: CHEBI:30911; KCl: CHEBI:32588,,,,,gene disruption; gene complementation,,,RP,24320078,PubMed,10.1111/1462-2920.12352,,keyhani@ufl.edu,,Z Luo 2013,2013,1 gene,Luo-2013-Ablation of the creA,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5438,PHI:3993,UniProt,Q5A2J7,GenBank,EAK96981,,,SC5314,Yvc1,,,,,,,5476,Candida albicans,,DAY1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,vacuolar calcium channel,,,,reduced virulence,,,,,,,,reduced,,no,SDS; ethanol,SDS: CHEBI:8984; ethanol: CHEBI:16236,,,,,gene disruption; gene complementation,,,RP,24368068,PubMed,10.1016/j.ijmm.2013.11.022,,nklimingchun@163.com,"Although the mutant showed no difference in sensitivity to calcium-depleted, calcium-rich or alkaline pH conditions when compared to the wild-type and reconstituted strains, it was hypersensitive to the membrane perturbing agent SDS and high-level ethanol",Q Yu 2013,2013,1 gene,Yu-2013-A novel role of the,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5439,PHI:3994,UniProt,O25175,GenBank,AAD07485,,,26695,aCgT,,,,,,,210,Helicobacter pylori,85962,26695,peptic ulcer disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,stomach,cholesteryl a-glucosyltransferase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24312443,PubMed,10.1371/journal.pone.0078191,,minoru@sanfordburnham.org,"These results strongly suggest that cholesteryl a-glucosides induce an immune response causing increased inflammation, yet that response decreases the number of surviving H. pylori.",Y Ito 2013,2013,1 gene,Ito-2013-Helicobacter pylori,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5440,PHI:3995,UniProt,E4QG66,GenBank,ADQ29586,,,N40,HrpA,,,,,,,139,Borreliella burgdorferi,,GCB920,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,bladder; heart; knee,DEAH-box RNA helicase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,24367266,PubMed,10.1371/journal.ppat.1003841,,chaconas@ucalgary.ca,,A Salman-Dilgimen 2013,2013,1 gene,"Salman-Dilgimen-2013-HrpA, an RNA Helicas",Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5441,PHI:3996,UniProt,I1RZL3,BROAD,FGSG_09862.3,,,PH-1,FgFim,,,,,,,5518,Fusarium graminearum,,Y2021A,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 5,,,spikelet,"fimbrin is a cytoskeletal protein associated with microfilament core bundles in microvilli, microspikes, stereocilia, membrane ruffles, and cell-substratum attachment sites.",,,,reduced virulence,,,,,,reduced,reduced,reduced; aberrant,reduced,no,JS399-19; LiCl; CaCl2; ZnCl2; SDS; Congo red; caffeine; NaCl; KCl; H2O2,LiCl: CHEBI:48607; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976; caffeine: CHEBI:27732; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,RP,24299032,PubMed,10.1111/mpp.12108,,mgzhou@njau.edu.cn,"Deletion mutants showed a dramatic decrease in resistance to JS399-19; increased sensitivity to diverse metal cations, to agents that induce osmotic stress and oxidative stress, and to agents that damage the cell membrane and cell wall.",Z ZHENG 2013,2013,1 gene,"Zheng-2013-FgFim, a key protein",Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5442,PHI:3997,UniProt,Q5KBN3,GenBank,AAW45521,,,JEC21,znf2,,,,,,,5207,Cryptococcus neoformans,1396488,XL280,,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung; brain; spleen; kidney,zinc finger transcription factor,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,23670559,PubMed,10.1128/IAI.00259-13,,xlin@bio.tamu.edu,,B Zhai 2013,2013,1 gene,Zhai-2013-Congenic strains of,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5443,PHI:3997,UniProt,Q5KBN3,GenBank,AAW45521,,,JEC21,znf2,,,,,,,5207,Cryptococcus neoformans,1396488,XL280,,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung; brain; spleen; kidney,zinc finger transcription factor,,,,unaffected pathogenicity,yes,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,23670559,PubMed,10.1128/IAI.00259-13,,xlin@bio.tamu.edu,,B Zhai 2013,2013,1 gene,Zhai-2013-Congenic strains of,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5444,PHI:3998,UniProt,E3KNM7,GenBank,EFP85902,,,75-36-700-3,Pgt-IaaM,,,,,,,5297,Puccinia graminis,418459,f. sp. tritici strain CRL 75-36-700-3,stem rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. McNair 701,,,leaf,encoding a putative tryptophan 2 monooxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24350783,PubMed,10.1094/MPMI-09-13-0289-FI,,scot_hulbert@wsu.edu,,C Yin 2013,2013,1 gene,Yin-2013-Characterization of,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5445,PHI:3999,UniProt,A6QGB6,GenBank,BAF67398,,,Newman,FMT,,,,,,,1280,Staphylococcus aureus,,WCUH29,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney,formyl methionyl transferase,,,,reduced virulence,,,,,,,,reduced,,no,azithromycin; erythromycin; tylosin; telithromycin; lincomycin; virginiamycin; tiamulin,azithromycin: CHEBI:2955; erythromycin: CHEBI:48923; tylosin: CHEBI:17658; lincomycin: CHEBI:6472,,,,,gene mutation,,,RP,23571548,PubMed,10.1128/AAC.00162-13,,Kelly.M.Aubart@gsk.com,"These mutants were 8- to 16-fold more sus-ceptible to antibiotics that interact with 50S ribosomal subunits, such as macrolides, ketolides, lincosamides, streptogramins, and pleuromutilins, than the wild-type parent strain.",T Lewandowski 2013,2013,1 gene,Lewandowski-2013-Staphylococcus aureu,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5446,PHI:4000,UniProt,G4NCH6,GenBank,EHA48273,,,70-15,Pex14,,,,,,,318829,Magnaporthe oryzae,,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,regulates the gamma-glutamyl cycle and GSH production,,,,unaffected pathogenicity,,,,,,wild type,,,,no,,,,,,,gene deletion,,,RP,24302988,PubMed,10.1371/journal.pone.0079128,,naweed@tll.org.s,,Y Deng 2013,2013,1 gene,Deng-2013-The role of snx41-ba,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5447,PHI:4001,UniProt,Q9KKH8,GenBank,AF005744_3,,,,ysaC,,,,,,,630,Yersinia enterocolitica,,JB580v,yersiniosis,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,Ysa T3SS are Ysc effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23630961,PubMed,10.1128/IAI.01454-12,,kawalker@med.unc.edu,S2 cell is a macrophage-like cell line,K A Walker 2013,2013,1 gene,Walker-2013-A phenotype at last_,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5448,PHI:4002,UniProt,P23926,GenBank,CAA41305,,,PAO1,anr,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,septicemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,oxygen-sensitive regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,no,gene deletion; gene complementation,,,RP,23667230,PubMed,10.1128/JB.02169-12,,deborah.a.hogan@dartmouth.edu,,A A Jackson 2013,2013,1 gene,Jackson-2013-Anr and its activati,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5449,PHI:4002,UniProt,P23926,GenBank,CAA41305,,,PAO1,anr,,,,,,,287,Pseudomonas aeruginosa,208964,PA14,septicemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,oxygen-sensitive regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,no,gene deletion; gene complementation,,,RP,23667230,PubMed,10.1128/JB.02169-12,,deborah.a.hogan@dartmouth.edu,,A A Jackson 2013,2013,1 gene,Jackson-2013-Anr and its activati,Batch035a,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5450,PHI:4003,UniProt,Q5ANE3,GenBank,EAL04308,,,SC5314,Nce102,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,MARVEL domain protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24281718,PubMed,10.1128/mBio.00723-13,,james.konopka@stonybrook.edu,,L M Douglas 2013,2013,1 gene,Douglas-2013-The MARVEL domain pr,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5451,PHI:4004,UniProt,B9A810,GenBank,BAH15044,,,TH3996,VopC,chromosome 2,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,acute gastroenteritis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,intestine,T3SS2 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24345190,PubMed,10.1111/cmi.12252,,kodama@biken.osaka-u.ac.jp,"although VopC can promote host cell invasion, such internalization is not a critical step of the disease process, consistent with the traditional view of V. parahaemolyticus as an extracellular pathogen.",R Okada 2013,2013,1 gene,Okada-2013-The Vibrio parahaemo,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5452,PHI:4005,UniProt,Q888Y8,GenBank,AAO5441,,,DC3000,HopD1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24329768,PubMed,10.1111/nph.12626,,jalfano2@unl.edu,,A Block 2013,2013,1 gene,Block-2013-The Pseudomonas syri,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5453,PHI:4006,UniProt,Q5X811,GenBank,CAH11591,,,Paris,sdhA,,,,,,,446,Legionella pneumophila,866628,130b,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung,dot/Icm effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23649096,PubMed,10.1128/IAI.00296-13,,g.frankel@imperial.ac.uk,,Clare R. Harding,2013,2 genes,Harding-2013-The Dot_Icm effector,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5454,PHI:4006,UniProt,Q5X811,GenBank,CAH11591,,,Paris,sdhA,,,,,,,446,Legionella pneumophila,866628,130b,Legionnaires' disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,dot/Icm effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23649096,PubMed,10.1128/IAI.00296-13,,g.frankel@imperial.ac.uk,,Clare R. Harding,2013,2 genes,Harding-2013-The Dot_Icm effector,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5455,PHI:4007,UniProt,B2C317,GenBank,ABY75869,,,2300/99 Alcoy,flaA,,,,,,,446,Legionella pneumophila,866628,130b,Legionnaires' disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23649096,PubMed,10.1128/IAI.00296-13,,g.frankel@imperial.ac.uk,,Clare R. Harding,2013,2 genes,Harding-2013-The Dot_Icm effector,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5456,PHI:4008,UniProt,Q887D0,GenBank,AAO54897,,,DC3000,HopM1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24324742,PubMed,10.1371/journal.pone.0082032,,mackey.86@osu.edu,,A Gangadharan 2013,2013,1 gene,Gangadharan-2013-The Pseudomonas syri,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5457,PHI:4009,UniProt,Q3BM44,GenBank,CAJ26169,,,85-10,xopQ,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial spot (pepper); bacterial spot (tomato),eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 20R,,,leaf,T3S effector,,,MAPKKK a/MEK2/SIPK,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24279912,PubMed,10.1111/tpj.12391,,guidos@post.tau.ac.il,Agrobacterium tumefaciens GV2260,D Teper 2014,2014,1 gene,Teper-2013-Xanthomonas euvesica,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5458,PHI:4009,UniProt,Q3BM44,GenBank,CAJ26169,,,85-10,xopQ,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial spot (pepper); bacterial spot (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7998,,,leaf,T3S effector,,,MAPKKK a/MEK2/SIPK,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24279912,PubMed,10.1111/tpj.12391,,guidos@post.tau.ac.il,Agrobacterium tumefaciens GV2260,D Teper 2014,2014,1 gene,Teper-2013-Xanthomonas euvesica,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5459,PHI:4010,UniProt,Q4ZHV5,GenBank,AAY26144,,,M93Sm,Plp,,,,,,,55601,Vibrio anguillarum,,M93Sm,vibriosis,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,,phosphatidylcholine-specific phospholipase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24279474,PubMed,10.1186/1471-2180-13-271,,dnelson@uri.edu,,L Li 2013,2013,2 genes,Li-2013-Characterization of,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5460,PHI:4010,UniProt,Q4ZHV5,GenBank,AAY26144,,,M93Sm,Plp,,,,,,PHI:4011,55601,Vibrio anguillarum,,M93Sm,vibriosis,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,,phosphatidylcholine-specific phospholipase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24279474,PubMed,10.1186/1471-2180-13-271,,dnelson@uri.edu,,L Li 2013,2013,2 genes,Li-2013-Characterization of,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5461,PHI:4011,UniProt,Q4ZHV4,GenBank,AAY26145,,,M93Sm,vah 1,,,,,,PHI:4010,55601,Vibrio anguillarum,,M93Sm,vibriosis,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,,phosphatidylcholine-specific phospholipase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24279474,PubMed,10.1186/1471-2180-13-271,,dnelson@uri.edu,,L Li 2013,2013,2 genes,Li-2013-Characterization of,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5462,PHI:4012,UniProt,Q830T5,GenBank,AAO82391,,,V583,ElrR,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,,Rgg-like regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23645602,PubMed,10.1128/JB.00121-13,,pascale.serror@jouy.inra.fr,,R Dumoulin 2013,2013,2 genes,Dumoulin-2013-Enterococcal Rgg-lik,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5463,PHI:4012,UniProt,Q830T5,GenBank,AAO82391,,,V583,ElrR,,,,,,PHI:4013,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,,Rgg-like regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23645602,PubMed,10.1128/JB.00121-13,,pascale.serror@jouy.inra.fr,,R Dumoulin 2013,2013,2 genes,Dumoulin-2013-Enterococcal Rgg-lik,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5464,PHI:4013,,no data found,GenBank,EF2686,,,V583,ElrA,,,,,,PHI:4012,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,,Rgg-like regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23645602,PubMed,10.1128/JB.00121-13,,pascale.serror@jouy.inra.fr,,R Dumoulin 2013,2013,2 genes,Dumoulin-2013-Enterococcal Rgg-lik,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5465,PHI:4014,UniProt,O50955,GenBank,AAC66256,,,B31,bba66,,,,,,,139,Borreliella burgdorferi,224326,B31,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,joint,immunogenic lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23630963,PubMed,10.1128/IAI.00140-13,,carrollja2@niaid.nih.gov,complementation through tick. tibiotarsal joint,T G Patton 2013,2013,1 gene,Patton-2013-Borrelia burgdorferi,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5466,PHI:4015,UniProt,Q4WLB9,GenBank,EAL89245,,,Af293,CfmA,,,,,,PHI:4016; PHI:4017,746128,Aspergillus fumigatus,,ku80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,cell-wall proteins,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,sodium dodecyl sulfate; calcofluor white; Congo red; caspofungin; nikkomycin Z; amphotericin B; voriconazole; menadione; H2O2; tunicamycin; dithiothreitol; EGTA,"SDS: CHEBI:8984; calcofluor white: CHEBI:50011; congo red: CHEBI:34653; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; nikkomycin   Z,  amphotericin B: CHEBI:2682; voriconazole: CHEBI:10023; menadione: CHEBI:28869; H2O2: CHEBI:16240; tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:17456; EGTA: CHEBI:30740",,,,,gene deletion: full; gene complementation,,,RP,24361821,PubMed,10.1016/j.fgb.2013.12.005,,nosherov@post.tau.ac.il,,Y Vaknin 2013,2013,3 genes,Vaknin-2013-The three Aspergillu,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5467,PHI:4016,UniProt,Q4WMA6,GenBank,EAL88908,,,Af293,CfmB,,,,,,PHI:4015; PHI:4017,746128,Aspergillus fumigatus,,ku80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,cell-wall proteins,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,sodium dodecyl sulfate; calcofluor white; Congo red; caspofungin; nikkomycin Z; amphotericin B; voriconazole; menadione; H2O2; tunicamycin; dithiothreitol; EGTA,"SDS: CHEBI:8984; calcofluor white: CHEBI:50011; congo red: CHEBI:34653; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; nikkomycin   Z,  amphotericin B: CHEBI:2682; voriconazole: CHEBI:10023; menadione: CHEBI:28869; H2O2: CHEBI:16240; tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:17456; EGTA: CHEBI:30740",,,,,gene deletion: full; gene complementation,,,RP,24361821,PubMed,10.1016/j.fgb.2013.12.005,,nosherov@post.tau.ac.il,,Y Vaknin 2013,2013,3 genes,Vaknin-2013-The three Aspergillu,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5468,PHI:4017,UniProt,Q4WNE1,GenBank,EAL88523,,,Af293,CfmC,,,,,,PHI:4015; PHI:4016,746128,Aspergillus fumigatus,,ku80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,cell-wall proteins,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,sodium dodecyl sulfate; calcofluor white; Congo red; caspofungin; nikkomycin Z; amphotericin B; voriconazole; menadione; H2O2; tunicamycin; dithiothreitol; EGTA,"SDS: CHEBI:8984; calcofluor white: CHEBI:50011; congo red: CHEBI:34653; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; nikkomycin   Z,  amphotericin B: CHEBI:2682; voriconazole: CHEBI:10023; menadione: CHEBI:28869; H2O2: CHEBI:16240; tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:17456; EGTA: CHEBI:30740",,,,,gene deletion: full; gene complementation,,,RP,24361821,PubMed,10.1016/j.fgb.2013.12.005,,nosherov@post.tau.ac.il,,Y Vaknin 2013,2013,3 genes,Vaknin-2013-The three Aspergillu,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5469,PHI:4018,UniProt,Q88BH0,GenBank,AAO53599,,,DC3000,hopK1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,flower,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24299018,PubMed,10.1111/tpj.12396,,jalfano2@unl.edu,,G Li 2013,2013,1 gene,Li-2013-Distinct Pseudomonas.pdf,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5470,PHI:4019,UniProt,J9N2X8,Ensembl Genomes,FOXG_09534T0,,,,FVS1,chromosome 9,,,,,,5507,Fusarium oxysporum,61369,f. sp. melonis race 2 strain Mel02010,wilt (melon),eudicots,3656,Cucumis melo (related: muskmelon),cv. Amus,,,leaf,WCMC-4_G03-encoding gene,,,,reduced virulence,,,,,delayed,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,24330129,PubMed,10.1111/1574-6968.12356,,y_iida@affrc.go.jp,,Y Iida 2013,2013,1 gene,"Iida-2013-Mutation of FVS1, en",Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5471,PHI:4020,UniProt,A7MVT5,GenBank,ABU71143,,,ATCC BAA-1116,hmgA,,,,,,,680,Vibrio campbellii,338187,BB120,luminous vibriosis,crustaceans,6687,Penaeus monodon (related: black tiger shrimp),,,,,"homogentisate-1,2-dioxygenase",,,catabolic pathway of tyrosine metabolism,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,24376440,PubMed,10.3389/fmicb.2013.00379,,zheng.wang@nrl.navy.mil,,Z Wang 2013,2013,1 gene,Wang-2013-Vibrio campbellii hm,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5472,PHI:4021,UniProt,G1XLT2,GenBank,EGX45923,,,ATCC 24927,AoMls,,,,,,,2813651,Orbilia oligospora,756982,CBS 115.81,nematode trapping fungus,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,malate synthase,,,glyoxylate cycle,reduced virulence,,,,,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full,,,RP,24323290,PubMed,10.1007/s00253-013-5432-6,,kqzhang1@ynu.edu.cn,growth s of deltaAoMls mutants were much slower than wild-type strains on liquid MM containing either sodium acetate or sodium oleate as the carbon source. Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.,X Zhao 2013,2013,1 gene,Zhao-2013-Malate synthase gene,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5473,PHI:4022,UniProt,Q05464,GenBank,CAA79893,,,S190,M1,,,,,,,1314,Streptococcus pyogenes,,5448,pharyngitis; necrotizing fasciitis; toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lymphoid tissue,binds fibrinogen to block phagocytosis and form a proinflammatory complex,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24356958,PubMed,10.1074/jbc.M113.529537,,vnizet@ucsd.edu,nasal-associated lymphoid tissue,E L Anderson 2013,2013,1 gene,Anderson-2013-The fibrinogen-bindi,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5474,PHI:4023,UniProt,I1RWW4,Broad,FGSG_08800,,,PH-1,Fgap1,chromosome 2,,,,,,5518,Fusarium graminearum,,INRA 605,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,bZip transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; sorbitol; cadmium,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,RP,24349499,PubMed,10.1371/journal.pone.0083377,,mathilde.montibus@gmail.com,Fgap1 is involved in the regulation of stress response in F. graminearum,M Montibus 2013,2013,1 gene,Montibus-2013-The bZIP Transcripti,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5475,PHI:4023,UniProt,I1RWW4,Broad,FGSG_08800,,,PH-1,Fgap1,chromosome 2,,,,,,5518,Fusarium graminearum,,INRA 605,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,bZip transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; sorbitol; cadmium,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; cadmium: CHEBI:37249,,,,,altered gene expression / gene regulation: overexpression,,,RP,24349499,PubMed,10.1371/journal.pone.0083377,,mathilde.montibus@gmail.com,Fgap1 is involved in the regulation of stress response in F. graminearum,M Montibus 2013,2013,1 gene,Montibus-2013-The bZIP Transcripti,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5476,PHI:4024,UniProt,G4N740,GenBank,EHA49953,,,70-15,MoST1,chromosome 5,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Shin 2,,,leaf,hexose transporter-like protein,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,24372780,PubMed,10.1111/1574-6968.12369,,saitoh@ibrc.or.jp,,H Saitoh 2013,2013,1 gene,Saitoh-2013-MoST1 encoding a hex,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5477,PHI:4024,UniProt,G4N740,GenBank,EHA49953,,,70-15,MoST1,chromosome 5,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Nigrate,,,leaf,hexose transporter-like protein,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,24372780,PubMed,10.1111/1574-6968.12369,,saitoh@ibrc.or.jp,,H Saitoh 2013,2013,1 gene,Saitoh-2013-MoST1 encoding a hex,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5478,PHI:4024,UniProt,G4N740,GenBank,EHA49953,,,70-15,MoST1,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Ken54-20,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Nigrate,,,leaf,hexose transporter-like protein,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,24372780,PubMed,10.1111/1574-6968.12369,,saitoh@ibrc.or.jp,,H Saitoh 2013,2013,1 gene,Saitoh-2013-MoST1 encoding a hex,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5479,PHI:4024,UniProt,G4N740,GenBank,EHA49953,,,70-15,MoST1,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Ken53-33,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Nigrate,,,leaf,hexose transporter-like protein,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,24372780,PubMed,10.1111/1574-6968.12369,,saitoh@ibrc.or.jp,,H Saitoh 2013,2013,1 gene,Saitoh-2013-MoST1 encoding a hex,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5480,PHI:4024,UniProt,G4N740,GenBank,EHA49953,,,70-15,MoST1,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Ken54-20,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Shin 2,,,leaf,hexose transporter-like protein,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,24372780,PubMed,10.1111/1574-6968.12369,,saitoh@ibrc.or.jp,,H Saitoh 2013,2013,1 gene,Saitoh-2013-MoST1 encoding a hex,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5481,PHI:4024,UniProt,G4N740,GenBank,EHA49953,,,70-15,MoST1,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Ken53-33,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Shin 2,,,leaf,hexose transporter-like protein,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,24372780,PubMed,10.1111/1574-6968.12369,,saitoh@ibrc.or.jp,,H Saitoh 2013,2013,1 gene,Saitoh-2013-MoST1 encoding a hex,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5482,PHI:4025,UniProt,Q8XQE6,GenBank,CAD18432,,,GMI1000,PopS,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,stem,AvrE-family effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24281716,PubMed,10.1128/mBio.00875-13,,ecza@plantpath.wisc.edu,Agrobacterium tumefaciens GV3101,J M Jacobs 2013,2013,1 gene,Jacobs-2013-Ralstonia solanacear,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5483,PHI:4025,UniProt,Q8XQE6,GenBank,CAD18432,,,GMI1000,PopS,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,stem,AvrE-family effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24281716,PubMed,10.1128/mBio.00875-13,,ecza@plantpath.wisc.edu,Agrobacterium tumefaciens GV3101,J M Jacobs 2013,2013,1 gene,Jacobs-2013-Ralstonia solanacear,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5484,PHI:4025,UniProt,Q8XQE6,GenBank,CAD18432,,,GMI1000,PopS,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. Russet Norkotah,,,stem,AvrE-family effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24281716,PubMed,10.1128/mBio.00875-13,,ecza@plantpath.wisc.edu,Agrobacterium tumefaciens GV3101,J M Jacobs 2013,2013,1 gene,Jacobs-2013-Ralstonia solanacear,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5485,PHI:4026,UniProt,E4TAS8,GenBank,ADQ82438,,,ATCC 11845,sip,,,,,,,34085,Riemerella anatipestifer,1354240,serotype 1 strain CH3,epizootic infection (poultry),birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood,siderophore-i nteracting protein,,,,reduced virulence,,,,,,,,reduced,,no,2-2'-dipyridyl,2-2'-dipyridyl: CHEBI:30351,,,,,gene disruption; gene complementation,,,RP,24345412,PubMed,10.1016/j.vetmic.2013.11.027,,huqinghai@caas.cn,,J Tu 2013,2013,1 gene,Tu-2013-The siderophore-inte,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5486,PHI:4027,UniProt,J9Z755,GenBank,AFS51419,,,DE205B,AatB,,,,,,,562,Escherichia coli,,APEC DE205B,septicemia,birds,8839,Anas platyrhynchos (related: mallard),,,,lung,autotransporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23630958,PubMed,10.1128/IAI.00102-13,,daijianjun@njau.edu.cn,,X ZhuGe 2013,2013,1 gene,Zhuge-2013-Characterization and,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5487,PHI:4028,UniProt,Q8PHQ1,GenBank,NP_643506,,,306,ssuA,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Eureka,,,leaf,alkanesulphonate-binding protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,24282519,PubMed,10.1371/journal.pone.0080083,,andrea.balan@lnbio.cnpem.br,,F T d A 2013,2013,1 gene,Tofoli de Araujo-2013-Structural and Physi,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5488,PHI:4029,,no data found,,,,,PMS117,IG,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,cotyledon,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5489,PHI:4030,,no data found,GenBank,WP_017255686,,,PMS117,PTOL117_00705,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,cotyledon,hypothetical protein (3133 aa) in tolaasin biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5490,PHI:4031,,no data found,GenBank,WP_016972361,,,PMS117,PTOL117_19575,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,cotyledon,hypothetical protein (1642 aa) in tolaasin biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5491,PHI:4032,,no data found,GenBank,WP_016972709,,,PMS117,gltB,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,cotyledon,glutamate synthase large chain (472 aa) in glutamate synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5492,PHI:4033,,no data found,GenBank,WP_017256421,,,PMS117,trpC,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,cotyledon,indole-3-glycerol phosphate synthase (278 aa) in tryptophan synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5493,PHI:4034,,no data found,GenBank,WP_016970746,,,PMS117,argF,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,cotyledon,ornithine carbamoyltransferase (306 aa) in arginine synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5494,PHI:4035,,no data found,GenBank,WP_016972708,,,PMS117,gltD,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,cotyledon,glutamate synthase small chain (125 aa) in glutamate synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5495,PHI:4029,,no data found,,,,,PMS117,IG,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),basidiomycetes,5341,Agaricus bisporus (related: cultivated mushroom),,,,cotyledon,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5496,PHI:4030,,no data found,GenBank,WP_017255686,,,PMS117,PTOL117_00705,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),basidiomycetes,5341,Agaricus bisporus (related: cultivated mushroom),,,,cotyledon,hypothetical protein (3133 aa) in tolaasin biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5497,PHI:4031,,no data found,GenBank,WP_016972361,,,PMS117,PTOL117_19575,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),basidiomycetes,5341,Agaricus bisporus (related: cultivated mushroom),,,,cotyledon,hypothetical protein (1642 aa) in tolaasin biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5498,PHI:4032,,no data found,GenBank,WP_016972709,,,PMS117,gltB,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),basidiomycetes,5341,Agaricus bisporus (related: cultivated mushroom),,,,cotyledon,glutamate synthase large chain (472 aa) in glutamate synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5499,PHI:4033,,no data found,GenBank,WP_017256421,,,PMS117,trpC,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),basidiomycetes,5341,Agaricus bisporus (related: cultivated mushroom),,,,cotyledon,indole-3-glycerol phosphate synthase (278 aa) in tryptophan synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5500,PHI:4034,,no data found,GenBank,WP_016970746,,,PMS117,argF,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),basidiomycetes,5341,Agaricus bisporus (related: cultivated mushroom),,,,cotyledon,ornithine carbamoyltransferase (306 aa) in arginine synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5501,PHI:4035,,no data found,GenBank,WP_016972708,,,PMS117,gltD,,,,,,,29442,Pseudomonas tolaasii,1161101,6264,brown blotch (mushroom),basidiomycetes,5341,Agaricus bisporus (related: cultivated mushroom),,,,cotyledon,glutamate synthase small chain (125 aa) in glutamate synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24370573,PubMed,10.1016/j.resmic.2013.12.001,,youhee@cha.ac.kr,,I Chung 2013,2013,7 genes,Chung-2013-Common virulence fac,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5502,PHI:4036,UniProt,I7GGT7,GenBank,AFP43229,,,ETX21512,ETX,,,,,,,1502,Clostridium perfringens,107819,type D strain CN1020,enterotoxemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract; brain; kidney; lung; heart; spleen; liver,involved in epsilon (ETX) toxin production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,23630957,PubMed,10.1128/IAI.00238-13,,fuzal@cahfs.ucdavis.edu,,J P Garcia 2013,2013,1 gene,Garcia-2013-Epsilon toxin is ess,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5503,PHI:4037,UniProt,A6QFU3,GenBank,BAF67225,,,Newman,cydB,,,,,,,1280,Staphylococcus aureus,,,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,heart,terminal oxidases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24302255,PubMed,10.1128/mBio.00976-13,,friedrich.goetz@uni-tuebingen.de,,F Götz 2013,2013,2 genes,Gotz-2013-Both terminal oxidas,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5504,PHI:4038,UniProt,A6QFR9,GenBank,BAF67201,,,Newman,qoxB,,,,,,,1280,Staphylococcus aureus,,,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,liver,terminal oxidases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24302255,PubMed,10.1128/mBio.00976-13,,friedrich.goetz@uni-tuebingen.de,,F Götz 2013,2013,2 genes,Gotz-2013-Both terminal oxidas,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5505,PHI:4039,UniProt,A4VUT3,GenBank,ABP89872,,,05ZYH33,NisK,,,,,,PHI:4040,1307,Streptococcus suis,,ZY05719,pneumonia; endocarditis; meningitis; arthritis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; lung; brain; blood,two-component signal-transduction systems,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24342108,PubMed,10.1016/j.micres.2013.11.002,,tanchen@mail.hzau.edu.cn,,J Xu 2013,2013,2 genes,Xu-2013-The two-component sy,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5506,PHI:4040,UniProt,A4VUT4,GenBank,ABP89873,,,05ZYH33,NisR,,,,,,PHI:4039,1307,Streptococcus suis,,ZY05719,pneumonia; endocarditis; meningitis; arthritis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; lung; brain; blood,two-component signal-transduction systems,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24342108,PubMed,10.1016/j.micres.2013.11.002,,tanchen@mail.hzau.edu.cn,,J Xu 2013,2013,2 genes,Xu-2013-The two-component sy,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5507,PHI:4041,UniProt,I1RMA5,GenBank,ESU11009,,,PH-1,spt3,,,,,,,5518,Fusarium graminearum,,2021,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Yangmai 49,,,spikelet,transcription factor,,,,reduced virulence,yes,,,,,reduced,,reduced; aberrant,,no,NaCl; KCl; caffeine; SDS; Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; caffeine: CHEBI:27732; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CAS:151-21-3,,,,,gene mutation; gene complementation,,,RP,24289742,PubMed,10.1111/1574-6968.12350,,mgzhou@njau.edu.cn,,T Gao 2013,2013,2 genes,Gao-2013-Transcription factor,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5508,PHI:4042,UniProt,I1RGE1,GenBank,ESU10513,,,PH-1,spt8,,,,,,,5518,Fusarium graminearum,,2021,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Yangmai 49,,,spikelet,transcription factor,,,,reduced virulence,yes,,,,,reduced,,reduced; aberrant,,no,NaCl; KCl; caffeine; SDS; Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; caffeine: CHEBI:27732; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CAS:151-21-3,,,,,gene mutation; gene complementation,,,RP,24289742,PubMed,10.1111/1574-6968.12350,,mgzhou@njau.edu.cn,,T Gao 2013,2013,2 genes,Gao-2013-Transcription factor,Batch035b,2014-01-01,MC,,,,,,,,,,,,,
,,Record 5509,PHI:4043,UniProt,D4HXR8,GenBank,CBA21871,,,CFBP1430,AcrD,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),MM106,,,root,a resistance-nodulation-cell division (RND) transporter,,,envelope stress signal transduction pathway,unaffected pathogenicity,,,,,,,,,,no,nitrofurantoin; erythromycin; silver nitrate; sodium tungstate,nitrofurantoin: CHEBI:71415; erythromycin: CHEBI:48923; silver nitrate: CHEBI:32130; sodium tungstate: CHEBI:63940,,,,,gene disruption; gene complementation,,,RP,24443882,PubMed,10.1186/1471-2180-14-13,,h.weingart@jacobs-university.de,"The acrD mutant was 2-fold more sensitive to nitrofurantoin, erythromycin, silver nitrate and sodium tungstate i n comparison to the wild type.",D Pletzer 2014,2014,1 gene,Pletzer-2014-Characterization of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5510,PHI:4043,UniProt,D4HXR8,GenBank,CBA21871,,,CFBP1430,AcrD,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,a resistance-nodulation-cell division (RND) transporter,,,envelope stress signal transduction pathway,unaffected pathogenicity,,,,,,,,,,no,nitrofurantoin; erythromycin; silver nitrate; sodium tungstate,nitrofurantoin: CHEBI:71415; erythromycin: CHEBI:48923; silver nitrate: CHEBI:32130; sodium tungstate: CHEBI:63940,,,,,gene disruption; gene complementation,,,RP,24443882,PubMed,10.1186/1471-2180-14-13,,h.weingart@jacobs-university.de,"The acrD mutant was 2-fold more sensitive to nitrofurantoin, erythromycin, silver nitrate and sodium tungstate i n comparison to the wild type.",D Pletzer 2014,2014,1 gene,Pletzer-2014-Characterization of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5511,PHI:4044,UniProt,Q6GD52,GenBank,CAG41810,,,MSSA476,tirS,chromosome SCC476,,,,,,1280,Staphylococcus aureus,282459,MSSA476,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; kidney; spleen; liver; heart; brain; blood,TIR domain protein,,,NF-kappaB and MAPK signal-ing pathways,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24481289,PubMed,10.1159/000357618,,mona.johannessen@uit.no,,F Askarian 2014,2014,1 gene,Askarian-2014-A Staphylococcus aur,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5512,PHI:4045,UniProt,Q5AAI8,GenBank,EAK99743,,,SC5314,Nap1,chromosome R,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,septin regulator,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,24496790,PubMed,10.1128/mBio.00915-13,,mcbwangy@imcb.a-star.edu.sg,,Z Huang 2014,2014,1 gene,Huang-2014-Phosphoregulation of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5513,PHI:4046,UniProt,Q5ABY5,GenBank,EAL00232,,,SC5314,hpd1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,enzyme catalysing the oxidation of 3-hydroxypropionate,,,beta-oxidation pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,24497638,PubMed,10.1074/jbc.M113.517672,,Matthias.brock@hki-jena.de,,C Otzen 2014,2014,1 gene,Otzen-2014-Candida albicans uti,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5514,PHI:4047,,no data found,GenBank,ELX72309,,,SL1438,SPI-6,,,,,,,28901,Salmonella enterica,439851,subsp. enterica serovar Dublin strain CT_02021853,systemic disease (cattle),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cecum; liver; spleen,type VI secretion system,,,beta-oxidation pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,24405577,PubMed,10.1186/1297-9716-45-2,,icontrer@uchile.cl,,D Pezoa 2014,2014,2 genes,Pezoa-2014-Only one of the two,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5515,PHI:4048,,no data found,GenBank,SeD_A1212-SeD_A1243,,,,SPI-19,,,,,,,28901,Salmonella enterica,439851,subsp. enterica serovar Dublin strain CT_02021853,systemic disease (cattle),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cecum; liver; spleen,type VI secretion system,,,beta-oxidation pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,24405577,PubMed,10.1186/1297-9716-45-2,,icontrer@uchile.cl,,D Pezoa 2014,2014,2 genes,Pezoa-2014-Only one of the two,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5516,PHI:4047,,no data found,GenBank,ELX72309,,,SL1438,SPI-6,,,,,,,28901,Salmonella enterica,439851,subsp. enterica serovar Dublin strain CT_02021853,systemic disease (cattle),birds,9031,Gallus gallus (related: chicken),White Leghorn,,,cecum; liver; spleen,type VI secretion system,,,beta-oxidation pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,24405577,PubMed,10.1186/1297-9716-45-2,,icontrer@uchile.cl,,D Pezoa 2014,2014,2 genes,Pezoa-2014-Only one of the two,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5517,PHI:4048,,no data found,GenBank,SeD_A1212-SeD_A1243,,,,SPI-19,,,,,,,28901,Salmonella enterica,439851,subsp. enterica serovar Dublin strain CT_02021853,systemic disease (cattle),birds,9031,Gallus gallus (related: chicken),White Leghorn,,,cecum; liver; spleen,type VI secretion system,,,beta-oxidation pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,24405577,PubMed,10.1186/1297-9716-45-2,,icontrer@uchile.cl,,D Pezoa 2014,2014,2 genes,Pezoa-2014-Only one of the two,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5518,PHI:4047,,no data found,GenBank,ELX72309,,,SL1438,SPI-6,,,,,,PHI:4048,28901,Salmonella enterica,439851,subsp. enterica serovar Dublin strain CT_02021853,systemic disease (cattle),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cecum; liver; spleen,type VI secretion system,,,beta-oxidation pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,24405577,PubMed,10.1186/1297-9716-45-2,,icontrer@uchile.cl,,D Pezoa 2014,2014,2 genes,Pezoa-2014-Only one of the two,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5519,PHI:4048,,no data found,GenBank,SeD_A1212-SeD_A1243,,,,SPI-19,,,,,,PHI:4047,28901,Salmonella enterica,439851,subsp. enterica serovar Dublin strain CT_02021853,systemic disease (cattle),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cecum; liver; spleen,type VI secretion system,,,beta-oxidation pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,24405577,PubMed,10.1186/1297-9716-45-2,,icontrer@uchile.cl,,D Pezoa 2014,2014,2 genes,Pezoa-2014-Only one of the two,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5520,PHI:4047,,no data found,GenBank,ELX72309,,,SL1438,SPI-6,,,,,,PHI:4048,28901,Salmonella enterica,439851,subsp. enterica serovar Dublin strain CT_02021853,systemic disease (cattle),birds,9031,Gallus gallus (related: chicken),White Leghorn,,,cecum; liver; spleen,type VI secretion system,,,beta-oxidation pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,24405577,PubMed,10.1186/1297-9716-45-2,,icontrer@uchile.cl,,D Pezoa 2014,2014,2 genes,Pezoa-2014-Only one of the two,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5521,PHI:4048,,no data found,GenBank,SeD_A1212-SeD_A1243,,,,SPI-19,,,,,,PHI:4047,28901,Salmonella enterica,439851,subsp. enterica serovar Dublin strain CT_02021853,systemic disease (cattle),birds,9031,Gallus gallus (related: chicken),White Leghorn,,,cecum; liver; spleen,type VI secretion system,,,beta-oxidation pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,24405577,PubMed,10.1186/1297-9716-45-2,,icontrer@uchile.cl,,D Pezoa 2014,2014,2 genes,Pezoa-2014-Only one of the two,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5522,PHI:4049,UniProt,O00933,GenBank,CAA74178,,,BK,gra7,,,,,,,5811,Toxoplasma gondii,,RH,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,immunity related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24390541,PubMed,10.1073/pnas.1313501111,,sibley@wustl.edu,,A Alaganan 2014,2014,2 genes,Alaganan-2014-Toxoplasma GRA7 effe,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5523,PHI:4050,UniProt,A1E140,GenBank,ABK91937,,,CTG,rop18,,,,,,,5811,Toxoplasma gondii,,RH,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine-threonine protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24390541,PubMed,10.1073/pnas.1313501111,,sibley@wustl.edu,,A Alaganan 2014,2014,2 genes,Alaganan-2014-Toxoplasma GRA7 effe,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5524,PHI:4049,UniProt,O00933,GenBank,CAA74178,,,BK,gra7,,,,,,PHI:4050,5811,Toxoplasma gondii,,RH,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,immunity related,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24390541,PubMed,10.1073/pnas.1313501111,,sibley@wustl.edu,,A Alaganan 2014,2014,2 genes,Alaganan-2014-Toxoplasma GRA7 effe,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5525,PHI:4050,UniProt,A1E140,GenBank,ABK91937,,,CTG,rop18,,,,,,PHI:4049,5811,Toxoplasma gondii,,RH,toxoplasmic encephalitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine-threonine protein kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion; gene complementation,,,RP,24390541,PubMed,10.1073/pnas.1313501111,,sibley@wustl.edu,,A Alaganan 2014,2014,2 genes,Alaganan-2014-Toxoplasma GRA7 effe,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5526,PHI:4051,UniProt,G0X840,GenBank,AEK8693,,,RK123,tin2,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. Early Golden Bantam,,,leaf; stem,secreted effector,,,anthocyanin pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24473076,PubMed,10.7554/eLife.01355,,kahmann@mpi-marburg.mpg.de,,S Tanaka 2014,2014,1 gene,Tanaka-2014-A secreted Ustilago,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5527,PHI:4052,UniProt,Q0P864,GenBank,CAL35661,,,NCTC 11168,Cj1564,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168-O,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,cecum,chemoreceptor,,,,unaffected pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,24391495,PubMed,10.1371/journal.ppat.1003822,,v.korolik@griffith.edu.au,,H Rahman 2014,2014,1 gene,Rahman-2014-Characterisation of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5528,PHI:4053,UniProt,G4MPJ4,GenBank,XP_003710649,,,70-15,Pax1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,LIM domain-containing proteins,,,,loss of pathogenicity,no,yes,yes,,,reduced,,reduced,,no,NaCl; sorbitol; Congo red; sodium dodecyl sulfate (SDS); H2O2,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion; gene complementation,,,RP,24505448,PubMed,10.1371/journal.pone.0088246,,zhywang@zju.edu.cn,deletion of either PAX1 or LRG1 led to a decreased sensitivity to these cell wall-perturbing agent,Y Li 2014,2014,4 genes,Li-2014-Characterisation of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5529,PHI:4054,UniProt,G4MZD0,GenBank,XP_003713492,,,70-15,Lrg1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,LIM domain-containing proteins,,,,loss of pathogenicity,no,yes,yes,,,reduced,,reduced,,no,NaCl; sorbitol; Congo red; sodium dodecyl sulfate (SDS); H2O2,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion; gene complementation,,,RP,24505448,PubMed,10.1371/journal.pone.0088246,,zhywang@zju.edu.cn,deletion of either PAX1 or LRG1 led to a decreased sensitivity to these cell wall-perturbing agent,Y Li 2014,2014,4 genes,Li-2014-Characterisation of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5530,PHI:4055,UniProt,G4NF65,GenBank,XP_003719637,,,70-15,Rga1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,LIM domain-containing proteins,,,,unaffected pathogenicity,no,yes,yes,,,reduced,,,,no,NaCl; sorbitol; Congo red; sodium dodecyl sulfate (SDS); H2O2,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion; gene complementation,,,RP,24505448,PubMed,10.1371/journal.pone.0088246,,zhywang@zju.edu.cn,,Y Li 2014,2014,4 genes,Li-2014-Characterisation of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5531,PHI:4056,UniProt,G4N0E4,GenBank,XP_003712085,,,70-15,Ldp1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,LIM domain-containing proteins,,,,unaffected pathogenicity,no,no,no,,,,,,,no,NaCl; sorbitol; Congo red; sodium dodecyl sulfate (SDS); H2O2,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion; gene complementation,,,RP,24505448,PubMed,10.1371/journal.pone.0088246,,zhywang@zju.edu.cn,,Y Li 2014,2014,4 genes,Li-2014-Characterisation of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5532,PHI:4053,UniProt,G4MPJ4,GenBank,XP_003710649,,,70-15,Pax1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,LIM domain-containing proteins,,,,loss of pathogenicity,no,yes,yes,,,reduced,,reduced,,no,NaCl; sorbitol; Congo red; sodium dodecyl sulfate (SDS); H2O2,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion; gene complementation,,,RP,24505448,PubMed,10.1371/journal.pone.0088246,,zhywang@zju.edu.cn,deletion of either PAX1 or LRG1 led to a decreased sensitivity to these cell wall-perturbing agent,Y Li 2014,2014,4 genes,Li-2014-Characterisation of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5533,PHI:4054,UniProt,G4MZD0,GenBank,XP_003713492,,,70-15,Lrg1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,LIM domain-containing proteins,,,,loss of pathogenicity,no,yes,yes,,,reduced,,reduced,,no,NaCl; sorbitol; Congo red; sodium dodecyl sulfate (SDS); H2O2,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion; gene complementation,,,RP,24505448,PubMed,10.1371/journal.pone.0088246,,zhywang@zju.edu.cn,deletion of either PAX1 or LRG1 led to a decreased sensitivity to these cell wall-perturbing agent,Y Li 2014,2014,4 genes,Li-2014-Characterisation of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5534,PHI:4055,UniProt,G4NF65,GenBank,XP_003719637,,,70-15,Rga1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,LIM domain-containing proteins,,,,unaffected pathogenicity,no,yes,yes,,,reduced,,,,no,NaCl; sorbitol; Congo red; sodium dodecyl sulfate (SDS); H2O2,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion; gene complementation,,,RP,24505448,PubMed,10.1371/journal.pone.0088246,,zhywang@zju.edu.cn,,Y Li 2014,2014,4 genes,Li-2014-Characterisation of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5535,PHI:4056,UniProt,G4N0E4,GenBank,XP_003712085,,,70-15,Ldp1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,LIM domain-containing proteins,,,,unaffected pathogenicity,no,no,no,,,,,,,no,NaCl; sorbitol; Congo red; sodium dodecyl sulfate (SDS); H2O2,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion; gene complementation,,,RP,24505448,PubMed,10.1371/journal.pone.0088246,,zhywang@zju.edu.cn,,Y Li 2014,2014,4 genes,Li-2014-Characterisation of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5536,PHI:4057,UniProt,B6V9Y6,GenBank,FJ349604,,,,PsMPK1,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,SLT2-type mitogen-activated protein kinase,,,,reduced virulence,no,,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24480463,PubMed,10.1016/j.fgb.2014.01.003,,wangyc@njau.edu.cn,Silencing of PsMPK1 leads to increasing hypersensitivity to cell wall-degrading enzymes,A Li 2014,2014,1 gene,"Li-2014-PsMPK1, an SLT2-type",Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5537,PHI:4058,UniProt,Q9I194,GenBank,AE004664_10,,,PAO1,PvdQ,,,,,,,292,Burkholderia cepacia,,H111,life-threatening infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,quorum-quenching acylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24474783,PubMed,10.1073/pnas.1311263111,,w.j.quax@rug.nl,"PvdQ, aneffective quorum-quenching enzyme from Pseudomonas aeruginosa was mutated and expressed in Burkholderia cepacia- its pathogenticity was then tested on greater wax moth.",G Koch 2014,2014,1 gene,Koch-2014-Reducing virulence o,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5538,PHI:4059,UniProt,S5MFY0,GenBank,KC771245,,,N-5-1,HrpW,,,,,,,71657,Lonsdalea quercina,1331041,N-5-1,bark canker (poplar),eudicots,3690,Populus x canadensis (related: carolina poplar),cv. 74/76,,,bark,pectate lyase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24395334,PubMed,10.1002/jobm.201300342,,hewei@bjfu.edu.cn,,L Yang 2014,2014,1 gene,Yang-2014-The HrpW protein of,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5539,PHI:4060,UniProt,C9X850,GenBank,YP_005231421,,,D23580,st313-td,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ST313,food poisoning,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,involved in invasiveness and drug resistance,,,,reduced virulence,,,,,,,,reduced,,,,,,,,,gene deletion; gene complementation,,,RP,24404174,PubMed,10.1371/journal.pone.0084566,,ahefr@sund.ku.dk,,A Fresno 2014,2014,1 gene,Herrero-Fresno-2014-The role of the st31,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5540,PHI:4061,UniProt,Q2A4B4,GenBank,CAJ79126,,,LVS,EmrA1,,,,,,,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,resistance to oxidative stress,,,,reduced virulence,,,,,,,,reduced,,,H2O2; nalidixic acid; neomycin; streptomycin; tetracycline,H2O2: CHEBI:16240; nalidixic acid: CHEBI:100147; neomycin: CHEBI:7507; streptomycin: CHEBI:17076; tetracycline: CHEBI:27902,,,,,gene mutation; gene complementation,,,RP,24397487,PubMed,10.1111/mmi.12509,,Meenakshi.Malik@acphs.edu,,Z Ma 2014,2014,1 gene,Ma-2014-EmrA1 membrane fusio,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5541,PHI:4062,UniProt,Q83YM6,GenBank,AF461560_2,,,ATCC 11528,HopX1,,,,,,,317,Pseudomonas syringae,322,pv. tabaci,wildfire disease,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III effector,,,JA pathway,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host,,,RP,24558350,PubMed,10.1371/journal.pbio.1001792,,selena.gimenez@cnb.csic.es,,S Gimenez-Ibanez 2014,2014,1 gene,Gimenez-Ibanez-2014-The Bacterial Effect,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5542,PHI:4063,UniProt,Q7CFV3,GenBank,AE014000_4,,,KIM10+,Crp,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,24520064,PubMed,10.1128/mBio.01038-13,,athem@northwestern.edu,,W W Lathem 2014,2014,2 genes,Lathem-2014-Posttranscriptional,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5543,PHI:4064,UniProt,Q8ZIW2,GenBank,CAL19055,,,CO92,Hfq,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,RNA-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,24520064,PubMed,10.1128/mBio.01038-13,,athem@northwestern.edu,,W W Lathem 2014,2014,2 genes,Lathem-2014-Posttranscriptional,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5544,PHI:4065,UniProt,G4NBR8,GenBank,EHA48976,,,70-15,MoMsn2,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,zinc finger protein,,,cell wall biosynthesis pathway.,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced; aberrant,,no,NaCl. sorbitol; CFW,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,RP,24405033,PubMed,10.1094/MPMI-09-13-0271-R,,zhgzhang@njau.edu.cn,"deltaMomsn2 mutant was tolerant to the cell wall stressor Calcofluor white, it was sensitive to common osmotic stressors.",H Zhang 2014,2014,1 gene,Zhang-2014-Pleiotropic Function,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5545,PHI:4066,UniProt,F7WEI7,GenBank,AEJ45972,,,CCDC5079,lpqS,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,copper-responsive RicR regulon,,,,increased virulence (hypervirulence),,,,,,,,,,no,Cu,copper(2+): CHEBI:29036,,,,,gene mutation; gene complementation,,,RP,24549843,PubMed,10.1128/mBio.00876-13,,marie.samanovic@nyumc.org,"Deletion or disruption of individual RicR-regulated genes had no impact on virulence in mice, although several mutants had Cu hypersensitivity. In contrast, a mutant unable to activate the RicR regulon was not only highly susceptible to Cu but also attenuated in mice.",X Shi 2014,2014,5 genes,Shi-2014-The Copper-Responsiv,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5546,PHI:4067,UniProt,P95129,GenBank,AAA50944,,,,Rv2963,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,copper-responsive RicR regulon,,,,unaffected pathogenicity,,,,,,,,,,no,Cu,copper(2+): CHEBI:29036,,,,,gene mutation; gene complementation,,,RP,24549843,PubMed,10.1128/mBio.00876-13,,marie.samanovic@nyumc.org,"Deletion or disruption of individual RicR-regulated genes had no impact on virulence in mice, although several mutants had Cu hypersensitivity. In contrast, a mutant unable to activate the RicR regulon was not only highly susceptible to Cu but also attenuated in mice.",X Shi 2014,2014,5 genes,Shi-2014-The Copper-Responsiv,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5547,PHI:4068,UniProt,E2FZM4,GenBank,ADH04621,,,H37Rv,socA,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,copper-responsive RicR regulon,,,,unaffected pathogenicity,,,,,,,,,,no,Cu,copper(2+): CHEBI:29036,,,,,gene mutation; gene complementation,,,RP,24549843,PubMed,10.1128/mBio.00876-13,,marie.samanovic@nyumc.org,"Deletion or disruption of individual RicR-regulated genes had no impact on virulence in mice, although several mutants had Cu hypersensitivity. In contrast, a mutant unable to activate the RicR regulon was not only highly susceptible to Cu but also attenuated in mice.",X Shi 2014,2014,5 genes,Shi-2014-The Copper-Responsiv,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5548,PHI:4069,UniProt,P0CI28,GenBank,CCP42913,,,H37Rv,mymT,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,copper-responsive RicR regulon,,,,unaffected pathogenicity,,,,,,,,,,no,Cu,copper(2+): CHEBI:29036,,,,,gene mutation; gene complementation,,,RP,24549843,PubMed,10.1128/mBio.00876-13,,marie.samanovic@nyumc.org,"Deletion or disruption of individual RicR-regulated genes had no impact on virulence in mice, although several mutants had Cu hypersensitivity. In contrast, a mutant unable to activate the RicR regulon was not only highly susceptible to Cu but also attenuated in mice.",X Shi 2014,2014,5 genes,Shi-2014-The Copper-Responsiv,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5549,PHI:4070,UniProt,O07434,GenBank,ADJ67803,,,H37Rv,RicR,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,copper-responsive RicR regulon,,,,reduced virulence,,,,,,,,,,no,Cu,copper(2+): CHEBI:29036,,,,,gene mutation; gene complementation,,,RP,24549843,PubMed,10.1128/mBio.00876-13,,marie.samanovic@nyumc.org,"Deletion or disruption of individual RicR-regulated genes had no impact on virulence in mice, although several mutants had Cu hypersensitivity. In contrast, a mutant unable to activate the RicR regulon was not only highly susceptible to Cu but also attenuated in mice.",X Shi 2014,2014,5 genes,Shi-2014-The Copper-Responsiv,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5550,PHI:4071,UniProt,D5AF41,GenBank,ADE32434,,,GZ1,IMPDH,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,even-toed ungulates,9823,Sus scrofa (related: pig),,,,,inosine-5'-monophosphate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,mannose,mannose: CHEBI:37684,,,,,gene deletion: full,,,RP,24458764,PubMed,10.1007/s00284-014-0527-6,,zhoujm075@gmail.com,"Compared with wild type, the mutant lost the ability of utilize mannose, which might relate to down expression of TPI and GAPDH.",J Zhou 2014,2014,1 gene,Zhou-2014-Characterization and,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5551,PHI:4072,UniProt,A4IVU5,GenBank,ABO46047,,,WY96-3418,PdpC,,,,,,,263,Francisella tularensis,,SCHU P0,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,pathogenicity determinant protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24558472,PubMed,10.1371/journal.pone.0089075,,ktana@nih.go.jp,,A Uda 2014,2014,1 gene,Uda-2014-Role of Pathogenicit,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5552,PHI:4073,UniProt,V5XVU3,GenBank,BAO08779,,,2170,Ser,,,,,,,615,Serratia marcescens,,2170,hemolymph bleeding,moths,7091,Bombyx mori (related: domestic silkworm),,,,,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,24530643,PubMed,10.1016/j.jip.2014.02.001,,sekimizu@mol.f.u-tokyo.ac.jp,,K Ishii 2014,2014,3 genes,Ishii-2014-Identification of a,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5553,PHI:4074,UniProt,V6A547,GenBank,CDG14825,,,Db11,wecA,,,,,,,615,Serratia marcescens,,2170,hemolymph bleeding,moths,7091,Bombyx mori (related: domestic silkworm),,,,,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,24530643,PubMed,10.1016/j.jip.2014.02.001,,sekimizu@mol.f.u-tokyo.ac.jp,,K Ishii 2014,2014,3 genes,Ishii-2014-Identification of a,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5554,PHI:4075,UniProt,L0MK13,GenBank,AGB83016,,,FGI94,flhD,,,,,,,615,Serratia marcescens,,2170,hemolymph bleeding,moths,7091,Bombyx mori (related: domestic silkworm),,,,,virulence factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,24530643,PubMed,10.1016/j.jip.2014.02.001,,sekimizu@mol.f.u-tokyo.ac.jp,,K Ishii 2014,2014,3 genes,Ishii-2014-Identification of a,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5555,PHI:4076,UniProt,A4VTH6,GenBank,YP_001197815,,,05ZYH33,BgaC,,,,,,,1307,Streptococcus suis,391295,serotype 2 strain 05ZYH33,meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,b-galactosidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,24556915,PubMed,10.1038/srep04140,,science2008@hotmail.com,,D Hu 2014,2014,1 gene,Hu-2014-The beta-galactosida,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5556,PHI:4077,UniProt,B9J010,GenBank,ACM12722,,,Q1,entA,,,,,,,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5557,PHI:4078,UniProt,B7HJA4,GenBank,ACK60498,,,B4264,asba,,,,,,PHI:4079; PHI:4080; PHI:4081; PHI:4082; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5558,PHI:4079,UniProt,B7HJA5,GenBank,ACK61906,,,B4264,asbb,,,,,,PHI:4078; PHI:4080; PHI:4081; PHI:4082; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5559,PHI:4080,UniProt,B7HJA6,GenBank,ACK62451,,,B4264,asbc,,,,,,PHI:4078; PHI:4079; PHI:4081; PHI:4082; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5560,PHI:4081,UniProt,B7HJA7,GenBank,ACK61852,,,B4264,asbd,,,,,,PHI:4078; PHI:4079; PHI:4080; PHI:4082; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5561,PHI:4082,UniProt,B7HJA8,GenBank,ACK64024,,,B4264,asbe,,,,,,PHI:4078; PHI:4079; PHI:4080; PHI:4081; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5562,PHI:4083,UniProt,B7HJA9,GenBank,ACK63394,,,B4264,asbf,,,,,,PHI:4078; PHI:4079; PHI:4080; PHI:4081; PHI:4082,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5563,PHI:4077,UniProt,B9J010,GenBank,ACM12722,,,Q1,entA,,,,,,PHI:4078; PHI:4079; PHI:4080; PHI:4081; PHI:4082; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5564,PHI:4078,UniProt,B7HJA4,GenBank,ACK60498,,,B4264,asba,,,,,,PHI:4077; PHI:4079; PHI:4080; PHI:4081; PHI:4082; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5565,PHI:4079,UniProt,B7HJA5,GenBank,ACK61906,,,B4264,asbb,,,,,,PHI:4077; PHI:4078; PHI:4080; PHI:4081; PHI:4082; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5566,PHI:4080,UniProt,B7HJA6,GenBank,ACK62451,,,B4264,asbc,,,,,,PHI:4077; PHI:4078; PHI:4079; PHI:4081; PHI:4082; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5567,PHI:4081,UniProt,B7HJA7,GenBank,ACK61852,,,B4264,asbd,,,,,,PHI:4077; PHI:4078; PHI:4079; PHI:4080; PHI:4082; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5568,PHI:4082,UniProt,B7HJA8,GenBank,ACK64024,,,B4264,asbe,,,,,,PHI:4077; PHI:4078; PHI:4079; PHI:4080; PHI:4081; PHI:4083,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5569,PHI:4083,UniProt,B7HJA9,GenBank,ACK63394,,,B4264,asbf,,,,,,PHI:4077; PHI:4078; PHI:4079; PHI:4080; PHI:4081; PHI:4082,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; vomiting,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bacillibactin siderophore,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24550730,PubMed,10.1371/journal.ppat.1003935,,christina.nielsen@jouy.inra.fr,,D Segond 2014,2014,7 genes,Segond-2014-Iron Acquisition in,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5570,PHI:4084,UniProt,G4ND53,GenBank,EHA48395,,,70-15,MoPex19,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,peroxisomal membrane proteins import and peroxisomes maintainence,,,,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,reduced,no,H2O2; methyl viologen; Congo red,H2O2: CHEBI:16240; congo red: CHEBI:34653; methyl viologen (paraquat): CHEBI:34905,,,,,gene deletion: full; gene complementation,,,RP,24454828,PubMed,10.1371/journal.pone.0085252,,sungc01@sina.com,MoPEX19 played a role in the integrity of cell walls of M. Oryzae.,L Li 2014,2014,1 gene,"Li-2014-MoPex19, which is es",Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5571,PHI:4084,UniProt,G4ND53,GenBank,EHA48395,,,70-15,MoPex19,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,peroxisomal membrane proteins import and peroxisomes maintainence,,,,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,reduced,no,H2O2; methyl viologen; Congo red,H2O2: CHEBI:16240; congo red: CHEBI:34653; methyl viologen (paraquat): CHEBI:34905,,,,,gene deletion: full; gene complementation,,,RP,24454828,PubMed,10.1371/journal.pone.0085252,,sungc01@sina.com,MoPEX19 played a role in the integrity of cell walls of M. Oryzae.,L Li 2014,2014,1 gene,"Li-2014-MoPex19, which is es",Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5572,PHI:4085,,no data found,BROAD,B0510_3555,,,B05.10,BcLTF1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,GATA transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,RP,24415947,PubMed,10.1371/journal.pgen.1004040,,julia.schumacher@uni-muenster.de,The altered ROS homoeostasis of the mutants that is characterized by the overproduction of H2O2 and the hypersensitivity to oxidative stress and light.,J Schumacher 2014,2014,1 gene,Schumacher-2014-The transcription fa,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5573,PHI:4085,,no data found,BROAD,B0510_3555,,,B05.10,BcLTF1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,GATA transcription factor,,,,unaffected pathogenicity,,yes,,,,,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,altered gene expression / gene regulation: overexpression,,,RP,24415947,PubMed,10.1371/journal.pgen.1004040,,julia.schumacher@uni-muenster.de,The altered ROS homoeostasis of the mutants that is characterized by the overproduction of H2O2 and the hypersensitivity to oxidative stress and light.,J Schumacher 2014,2014,1 gene,Schumacher-2014-The transcription fa,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5574,PHI:4086,,no data found,,Clafu_183744,,,,CfWor1,,,,,,,5499,Fulvia fulva,,race 0WU,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker Cf-0,,,leaf,transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24521437,PubMed,10.1111/mmi.12535,,pierre.dewit@wur.nl,,Okmen et al.,2014,1 gene,Okmen-2014-Functional analysis,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5575,PHI:4086,,no data found,,Clafu_183744,,,,CfWor1,,,,,,,5499,Fulvia fulva,,race 0WU,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker Cf-0,,,leaf,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation,,,RP,24521437,PubMed,10.1111/mmi.12535,,pierre.dewit@wur.nl,,Okmen et al.,2014,1 gene,Okmen-2014-Functional analysis,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5576,PHI:4087,UniProt,Q44636,GenBank,AAA71986,,,UM23-1,AtxA,,,,,,,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5577,PHI:4088,UniProt,Q44643,GenBank,BAU02535,,,,pXO2,,,,,,,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5578,PHI:4089,UniProt,P13422,GenBank,AAM26108,,,A2012,pXO1,,,,,,,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5579,PHI:4090,UniProt,P13423,GenBank,AAA22637,,,Sterne,pag,,,,,,PHI:4091; PHI:4092,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5580,PHI:4091,UniProt,P40136,GenBank,AAA22374,,,,cya,,,,,,PHI:4090; PHI:4092,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5581,PHI:4092,UniProt,P15917,GenBank,AAA79216,,,pLF74,lef,,,,,,PHI:4090; PHI:4091,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5582,PHI:4087,UniProt,Q44636,GenBank,AAA71986,,,UM23-1,AtxA,,,,,,PHI:4090; PHI:4091; PHI:4092,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5583,PHI:4090,UniProt,P13423,GenBank,AAA22637,,,Sterne,pag,,,,,,PHI:4091; PHI:4092; PHI:4087,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5584,PHI:4091,UniProt,P40136,GenBank,AAA22374,,,,cya,,,,,,PHI:4090; PHI:4092; PHI:4087,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5585,PHI:4092,UniProt,P15917,GenBank,AAA79216,,,pLF74,lef,,,,,,PHI:4090; PHI:4091; PHI:4087,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5586,PHI:4088,UniProt,Q44643,GenBank,BAU02535,,,,pXO2,,,,,,PHI:4090; PHI:4091; PHI:4092,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5587,PHI:4090,UniProt,P13423,GenBank,AAA22637,,,Sterne,pag,,,,,,PHI:4091; PHI:4092; PHI:4088,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5588,PHI:4091,UniProt,P40136,GenBank,AAA22374,,,,cya,,,,,,PHI:4090; PHI:4092; PHI:4088,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5589,PHI:4092,UniProt,P15917,GenBank,AAA79216,,,pLF74,lef,,,,,,PHI:4090; PHI:4091; PHI:4088,1392,Bacillus anthracis,261591,Vollum,bacteremia,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,spleen; lung; brain; kidney; liver,toxin production,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24416317,PubMed,10.1371/journal.pone.0084947,,haiml@iibr.gov.il,,H Levy 2014,2014,6 genes,Levy-2014-Toxin-independent vi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5590,PHI:4093,,no data found,Broad,BC1G_14039.1,,,B05.10,Bcsas1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,Rab/GTPase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,24520899,PubMed,10.1094/MPMI-10-13-0314-R,,tsp@ibcas.ac.cn,"The gene is upregulated upon exposure to H2O2 stress, suggesting that Rab family genes in B. cinerea could respond to oxidative stress.",Z Zhang 2014,2014,1 gene,Zhang-2014-Knocking out Bcsas1,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5591,PHI:4094,UniProt,B5L7M5,GenBank,ACD37724,,,ATCC 43809,AtlL,,,,,,,28035,Staphylococcus lugdunensis,,,infective endocarditis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,autolysin,,,,reduced virulence,,,,,,,,reduced,,no,triton X-100; penicillin G; vancomycin; teicoplanin,Triton X-100: CHEBI:9750; penicillin G: CHEBI:17334; vancomycin: CHEBI:28001,,,,,gene deletion: full,,,RP,24393327,PubMed,10.1111/1574-6968.12374,,martine.pestel-caron@chu-rouen.fr,"The mutants showed lower susceptibility to Triton X-100, penicillin G, vancomycin and teicoplanin.",L Gibert 2014,2014,1 gene,Gibert-2014-The major autolysin,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5592,PHI:4095,UniProt,L0PRS3,GenBank,CCK33071,,,Vl18,Vta2,,,,,,,100787,Verticillium longisporum,,Vl43,early senescence; early ripening,eudicots,3708,Brassica napus (related: rape),,,,seedling,transcription activator of adhesion,,,,loss of pathogenicity,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,24433459,PubMed,10.1111/nph.12671,,gbraus@gwdg.de,"Vta2 is a major regulator of fungal pathogenesis, and controls host-plant root infection and H2O2 detoxification",V Tran 2014,2014,1 gene,Tran-2014-Verticillium transcr,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5593,PHI:4095,UniProt,L0PRS3,GenBank,CCK33071,,,Vl18,Vta2,,,,,,,100787,Verticillium longisporum,,Vl43,early senescence; early ripening,eudicots,4081,Solanum lycopersicum (related: tomato),,,,seedling; root,transcription activator of adhesion,,,,loss of pathogenicity,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,24433459,PubMed,10.1111/nph.12671,,gbraus@gwdg.de,"Vta2 is a major regulator of fungal pathogenesis, and controls host-plant root infection and H2O2 detoxification",V Tran 2014,2014,1 gene,Tran-2014-Verticillium transcr,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5594,PHI:4096,UniProt,V9MGK6,GenBank,AGF29563,,,XJZ2,FoOCH1,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,Fusarium wilt (banana),monocots,89151,Musa x paradisiaca (related: banana),cv. Cavendish,,,root,"encoding a putative a-1,6-mannosyltransferase",,,,reduced virulence,,,yes,yes,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24503549,PubMed,10.1016/j.fgb.2014.01.005,,zdjiang@scau.edu.cn,,M Li 2014,2014,1 gene,Li-2014-Functional character,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5595,PHI:4097,UniProt,I7B318,GenBank,AFO38409,,,N36,CovRS,,,,,,,1314,Streptococcus pyogenes,160490,group A serotype M1,gas pharyngitis; neurofibromatosis; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,regulation of virulence factors,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24452689,PubMed,10.1128/IAI.01458-13,,blei@montana.edu,,J Li 2014,2014,1 gene,Li-2014-Neutrophils Select H,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5596,PHI:4098,UniProt,B2SHS4,GenBank,ACD58584,,,PXO99A,filp,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,cyclic di-GMP receptor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24548063,PubMed,10.1094/MPMI-12-13-0371-R,,cyhe@caas.net.cn,,F Yang 2014,2014,2 genes,Yang-2014-The degenerate EAL-G,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5597,PHI:4099,UniProt,B2SNM9,GenBank,ACD60951,,,PXO99A,PXO_02715,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,interacts with filp,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24548063,PubMed,10.1094/MPMI-12-13-0371-R,,cyhe@caas.net.cn,,F Yang 2014,2014,2 genes,Yang-2014-The degenerate EAL-G,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5598,PHI:4100,UniProt,P0C5S5,GenBank,AAD12736,,,BB7,luxO,,,,,,,669,Vibrio harveyi,,BB120,cholera,crustaceans,6660,Artemia (related: brine shrimps),,,,larva,quorum sensing,,,,reduced virulence,,,,,,,,wild type,,no,phenamil methanesulfonate,phenamil methanesulfonate: CHEBI:452494,,,,,gene mutation,,,RP,24528485,PubMed,10.1111/1462-2920.12420,,Tom.Defoirdt@UGent.be,It was established that mutations in LuxO resulted in loss of motility. The effect of loss of motility on virulence was studied by using phenamil rather than the mutants to avoid pleitropic effects,Q Yang 2014,2014,1 gene,Yang-2014-Quorum sensing posit,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5599,PHI:4101,UniProt,Q63W37,GenBank,CAH35049,,,K96243,Eco,,,,,,,28450,Burkholderia pseudomallei,,K96423,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,serine protease inhibitor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,24462575,PubMed,10.1016/j.micpath.2014.01.001,,pmireland@dstl.gov.uk,,P M Ireland 2014,2014,1 gene,Ireland-2014-The serine protease,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5600,PHI:4102,UniProt,Q8FXL4,GenBank,AAN33263,,,1330,ibpA,,,,,,,29461,Brucella suis,204722,1330,brucellosis,rodents,10090,Mus musculus (related: house mouse),,,,macrophage,heat-shock chaperone,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24517122,PubMed,10.1111/lam.12231,,david.ocallaghan@univ-montp1.fr,,P Berta 2014,2014,1 gene,Berta-2014-The Brucella suis Ib,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5601,PHI:4103,UniProt,B2RKU3,GenBank,BAG33988,,,ATCC 33277,DPPIV,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,dipeptidyl peptidase IV,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence,,,RP,24532232,PubMed,10.1111/2049-632X.12156,,paul.cos@uantwerpen.be,"In a murine subcutaneous abscess model, the biofilm-forming isolates with high DPPIV activity proved to be pathogenic, while the nonbiofilm formers with low DPPIV activity did not induce abscesses. Proteins with lower activity.",S Clais 2014,2014,1 gene,Clais-2014-Importance of biofil,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5602,PHI:4104,UniProt,Q7VN44,GenBank,AAP95651,,,35000HP,hfq,,,,,,,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,skin,stationary-phase and virulence gene regulation,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,24520065,PubMed,10.1128/mBio.01081-13,,sspinola@iupui.edu,In vitro growth of the mutant was complimented with full lenght gene. No complimentation of virlence study mentioned,D Gangaiah 2014,2014,1 gene,Gangaiah-2014-Haemophilus ducreyi,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5603,PHI:4105,UniProt,Q8IFL9,GenBank,CAD49281,,,3D7,fikk4.2,chromosome 4,,,,,,5833,Plasmodium falciparum,36329,3D7,malaria,primates,9606,Homo sapiens (related: human),,,,erythrocyte,exported kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24530877,PubMed,10.1016/j.ijpara.2014.01.003,,brian.cooke@monash.edu,,L M Kats 2014,2014,1 gene,Kats-2014-An exported kinase (,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5604,PHI:4106,UniProt,P35651,GenBank,CAB58249,,,GMI1000,HpaP,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Marmande VR,,,leaf,modulates type III effector secretion,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24405562,PubMed,10.1111/mpp.12119,,fabienne.vailleau@toulouse.inra.fr,,D Lohou 2014,2014,1 gene,Lohou-2014-HpaP modulates type,Batch036,2014-03-01,MC,,,,,,,,,,,,,
,,Record 5605,PHI:4107,UniProt,J4WFU2,GenBank,EJP68795,,,ARSEF 2860,BbMBF1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,multiprotein bridging factors,,,,reduced virulence,,,,,,,,reduced; aberrant,wild type,no,NaCl; sorbitol; H2O2; menadione; Congo red,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; congo red: CHEBI:34653,,,,,gene disruption; gene complementation,,,RP,24612420,PubMed,10.1111/1462-2920.12450,,keyhani@ufl.edu,"Compared with wild type, the deltaBbMBF1 strain displayed increased sensitivity to UV-irradiation and to oxidative, osmotic and heat stress",S Ying 2014,2014,1 gene,Ying-2014-The transcriptional,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5606,PHI:4108,UniProt,A5F6S0,GenBank,ABQ20123,,,O395,fadD,,,,,,,666,Vibrio cholerae,345073,O395,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,ileum,encoding a long-chain fatty acyl coenzyme A (acyl-CoA) ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23918781,PubMed,10.1128/IAI.00722-13,,rukhsana@iicb.res.in,,E Chatterjee 2014,2014,2 genes,Chatterjee-2013-Reduced virulence of,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5607,PHI:4109,UniProt,A3GTF1,GenBank,EAZ71879,,,NCTC 8457,rseP,,,,,,PHI:4108,666,Vibrio cholerae,345073,O395,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,ileum,integral membrane protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23918781,PubMed,10.1128/IAI.00722-13,,rukhsana@iicb.res.in,,E Chatterjee 2014,2014,2 genes,Chatterjee-2013-Reduced virulence of,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5608,PHI:4108,UniProt,A5F6S0,GenBank,ABQ20123,,,O395,fadD,,,,,,PHI:4109,666,Vibrio cholerae,345073,O395,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,ileum,encoding a long-chain fatty acyl coenzyme A (acyl-CoA) ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23918781,PubMed,10.1128/IAI.00722-13,,rukhsana@iicb.res.in,,E Chatterjee 2014,2014,2 genes,Chatterjee-2013-Reduced virulence of,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5609,PHI:4110,UniProt,G4NB64,GenBank,EHA48826,,,70-15,MoVOSA,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,"velvet genes are key regulators of a number of cellular processes, including development, pathogenicity and secondary metabolism",,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,24632440,PubMed,10.1016/j.fgb.2014.02.011,,yonglee@snu.ac.kr,,H Kim 2014,2014,4 genes,Kim-2014-Comparative function,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5610,PHI:4111,UniProt,G4NEE4,GenBank,EHA49421,,,70-15,MoVELC,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,"velvet genes are key regulators of a number of cellular processes, including development, pathogenicity and secondary metabolism",,,,reduced virulence,,no,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,24632440,PubMed,10.1016/j.fgb.2014.02.011,,yonglee@snu.ac.kr,,H Kim 2014,2014,4 genes,Kim-2014-Comparative function,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5611,PHI:4112,UniProt,G4MUB2,GenBank,EHA54799,,,70-15,MoVELB,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,"velvet genes are key regulators of a number of cellular processes, including development, pathogenicity and secondary metabolism",,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,24632440,PubMed,10.1016/j.fgb.2014.02.011,,yonglee@snu.ac.kr,,H Kim 2014,2014,4 genes,Kim-2014-Comparative function,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5612,PHI:4113,UniProt,G4N5X8,GenBank,EHA49754,,,70-15,MoVEA,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,"velvet genes are key regulators of a number of cellular processes, including development, pathogenicity and secondary metabolism",,,,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,24632440,PubMed,10.1016/j.fgb.2014.02.011,,yonglee@snu.ac.kr,,H Kim 2014,2014,4 genes,Kim-2014-Comparative function,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5613,PHI:4114,UniProt,Q9L8G8,GenBank,AF204737_1,,,C7184O,SmcR,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,septicemia,rodents,10090,Mus musculus (related: house mouse),ICR,,,jejunum,quorum sensing regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,23897607,PubMed,10.1128/IAI.00561-13,,choish@snu.ac.kr,,S M Kim 2014,2014,1 gene,Kim-2013-LuxR homologue SmcR,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5614,PHI:4115,,no data found,GenBank,RSAU_000538,,,6850,RsaA,,,,,,,1280,Staphylococcus aureus,,RN6390,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; spleen; kidney,moderates invasiveness and favour chronic infections,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24651379,PubMed,10.1371/journal.ppat.1003979,,francois.vandenesch@univ-lyon1.fr,,C Romilly 2014,2014,1 gene,Romilly-2014-A Non-Coding RNA Pro,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5615,PHI:4116,UniProt,B5S9R7,GenBank,CAQ59876,,,IPO1609,RSIPO_04290,,,,,,PHI:4117; PHI:4118; PHI:4119; PHI:4120; PHI:4121,305,Ralstonia solanacearum,,UY031,brown rot (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,petiole; root,type 4 fimbrial biogenesis protein,,,,reduced virulence,,,,yes,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24625029,PubMed,10.1094/MPMI-07-13-0210-R,,msiri@fq.edu.uy,,M I Siri 2014,2014,6 genes,Siri-2014-New type IV pili rel,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5616,PHI:4117,UniProt,B5S9R8,GenBank,CAQ59877,,,IPO1609,RSIPO_04291,,,,,,PHI:4116; PHI:4118; PHI:4119; PHI:4120; PHI:4121,305,Ralstonia solanacearum,,UY031,brown rot (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,petiole; root,type 4 fimbrial biogenesis protein,,,,reduced virulence,,,,yes,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24625029,PubMed,10.1094/MPMI-07-13-0210-R,,msiri@fq.edu.uy,,M I Siri 2014,2014,6 genes,Siri-2014-New type IV pili rel,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5617,PHI:4118,UniProt,B5S9R9,GenBank,CAQ59878,,,IPO1609,RSIPO_04292,,,,,,PHI:4116; PHI:4117; PHI:4119; PHI:4120; PHI:4121,305,Ralstonia solanacearum,,UY031,brown rot (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,petiole; root,type 4 fimbrial biogenesis protein,,,,reduced virulence,,,,yes,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24625029,PubMed,10.1094/MPMI-07-13-0210-R,,msiri@fq.edu.uy,,M I Siri 2014,2014,6 genes,Siri-2014-New type IV pili rel,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5618,PHI:4119,UniProt,B5S9S0,GenBank,CAQ59879,,,IPO1609,RSIPO_04293,,,,,,PHI:4116; PHI:4117; PHI:4118; PHI:4120; PHI:4121,305,Ralstonia solanacearum,,UY031,brown rot (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,petiole; root,type 4 fimbrial biogenesis protein,,,,reduced virulence,,,,yes,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24625029,PubMed,10.1094/MPMI-07-13-0210-R,,msiri@fq.edu.uy,,M I Siri 2014,2014,6 genes,Siri-2014-New type IV pili rel,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5619,PHI:4120,UniProt,B5S9S1,GenBank,CAQ59880,,,IPO1609,RSIPO_04294,,,,,,PHI:4116; PHI:4117; PHI:4118; PHI:4119; PHI:4121,305,Ralstonia solanacearum,,UY031,brown rot (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,petiole; root,type 4 fimbrial biogenesis protein,,,,reduced virulence,,,,yes,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24625029,PubMed,10.1094/MPMI-07-13-0210-R,,msiri@fq.edu.uy,,M I Siri 2014,2014,6 genes,Siri-2014-New type IV pili rel,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5620,PHI:4121,UniProt,B5S9S2,GenBank,CAQ59881,,,IPO1609,RSIPO_04295,,,,,,PHI:4116; PHI:4117; PHI:4118; PHI:4119; PHI:4120,305,Ralstonia solanacearum,,UY031,brown rot (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,petiole; root,type 4 fimbrial biogenesis protein,,,,reduced virulence,,,,yes,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24625029,PubMed,10.1094/MPMI-07-13-0210-R,,msiri@fq.edu.uy,,M I Siri 2014,2014,6 genes,Siri-2014-New type IV pili rel,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5621,PHI:4122,UniProt,G0LUT6,GenBank,CCC88354,,,LGA251,citZ,,,,,,,1280,Staphylococcus aureus,,RN6390,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney; heart,siderophore staphylobactin biosynthesis,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,citrate,citrate: CHEBI:50744,,,,,gene mutation; gene complementation,,,RP,24666349,PubMed,10.1111/mmi.12593,,deh@uwo.ca,"addition of citrate could overcome the block in SA synthesis in a citZ mutant, and could also overcome the block in both SA and SB 291 synthesis in the citZ sbnG double mutants.",J R Sheldon 2014,2014,2 genes,Sheldon-2014-TCA cycle activity i,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5622,PHI:4123,UniProt,D3ERG1,GenBank,ADC36334,,,04-02981,sbnG,,,,,,,1280,Staphylococcus aureus,,RN6390,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney; heart,provides citrate for siderophore staphylobactin biosynthesis,,,,unaffected pathogenicity,,,,,,,,reduced,,no,citrate,citrate: CHEBI:50744,,,,,gene mutation; gene complementation,,,RP,24666349,PubMed,10.1111/mmi.12593,,deh@uwo.ca,"addition of citrate could overcome the block in SA synthesis in a citZ mutant, and could also overcome the block in both SA and SB 291 synthesis in the citZ sbnG double mutants.",J R Sheldon 2014,2014,2 genes,Sheldon-2014-TCA cycle activity i,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5623,PHI:4122,UniProt,G0LUT6,GenBank,CCC88354,,,LGA251,citZ,,,,,,PHI:4123,1280,Staphylococcus aureus,,RN6390,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney; heart,siderophore staphylobactin biosynthesis,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,citrate,citrate: CHEBI:50744,,,,,gene mutation; gene complementation,,,RP,24666349,PubMed,10.1111/mmi.12593,,deh@uwo.ca,"addition of citrate could overcome the block in SA synthesis in a citZ mutant, and could also overcome the block in both SA and SB 291 synthesis in the citZ sbnG double mutants.",J R Sheldon 2014,2014,2 genes,Sheldon-2014-TCA cycle activity i,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5624,PHI:4123,UniProt,D3ERG1,GenBank,ADC36334,,,04-02981,sbnG,,,,,,PHI:4122,1280,Staphylococcus aureus,,RN6390,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney; heart,provides citrate for siderophore staphylobactin biosynthesis,,,,reduced virulence,,,,,,,,reduced,,no,citrate,citrate: CHEBI:50744,,,,,gene mutation; gene complementation,,,RP,24666349,PubMed,10.1111/mmi.12593,,deh@uwo.ca,"addition of citrate could overcome the block in SA synthesis in a citZ mutant, and could also overcome the block in both SA and SB 291 synthesis in the citZ sbnG double mutants.",J R Sheldon 2014,2014,2 genes,Sheldon-2014-TCA cycle activity i,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5625,PHI:4124,UniProt,Q83C69,GenBank,AAO90768,,,RSA 493,OmpA,,,,,,,777,Coxiella burnetii,227377,Nine Mile Phase I,zoonotic Q fever,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,invasin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24651569,PubMed,10.1371/journal.ppat.1004013,,matteo.bonazzi@cpbs.cnrs.fr,,E Martinez,2014,1 gene,Martinez-2014-Identification of Om,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5626,PHI:4125,UniProt,E9F189,GenBank,EFY98899,,,ARSEF 23,MrpacC,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,pH-response transcription factor,,,,reduced virulence,,no,yes,yes,,,,reduced,,no,KCl; NaCl; LiCl; H2O2; CuSO4; MgSO4; sorbitol,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; LiCl: CHEBI:48607; CuSO4: CHEBI:23414; MgSO4: CHEBI:32599,,,,,gene deletion: full; gene complementation,,,RP,24612440,PubMed,10.1111/1462-2920.12451,,cswang@sibs.ac.cn,"Growth assays on a potato dextrose agar (PDA) adjusted at pH 4, 5.6, 8 and 10 demonstrated that delta MrpacC had impaired growth/ deletion of MrpacC increased the sensitivity of the mut-ant to metal ion toxicity instead of the failure against hyperosmotic stress",W Huang 2014,2014,1 gene,Huang-2014-MrpacC regulates spo,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5627,PHI:4126,UniProt,Q830A5,GenBank,AAO82580,,,V583,bgsA,,,,,,,1351,Enterococcus faecalis,,12030,enterococcal endocarditis,rodents,10116,Rattus norvegicus (related: norway rat),Wistar,,,heart,cell-wall glycolipids,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24637922,PubMed,10.1371/journal.pone.0091863,,johannes.huebner@med.uni-muenchen.de,,C Haller 2014,2014,2 genes,Haller-2014-Cell-Wall Glycolipid,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5628,PHI:4127,UniProt,Q830A6,GenBank,AAO82579,,,V583,bgsB,,,,,,,1351,Enterococcus faecalis,,12030,enterococcal endocarditis,rodents,10116,Rattus norvegicus (related: norway rat),Wistar,,,heart,cell-wall glycolipids,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24637922,PubMed,10.1371/journal.pone.0091863,,johannes.huebner@med.uni-muenchen.de,,C Haller 2014,2014,2 genes,Haller-2014-Cell-Wall Glycolipid,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5629,PHI:4128,UniProt,B4EBZ0,GenBank,CAR51267,,,J2315,BCAL0960,,,,,,,95486,Burkholderia cenocepacia,985076,K56-2,cystic fibrosis,monocots,4472,Lemna minor (no common name found),,,,,O-oligosaccharyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24673753,PubMed,10.1111/mmi.12540,,jon.dennis@ualberta.ca,,K V Lithgow 2014,2014,1 gene,Lithgow-2014-A general protein O-,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5630,PHI:4128,UniProt,B4EBZ0,GenBank,CAR51267,,,J2315,BCAL0960,,,,,,,95486,Burkholderia cenocepacia,985076,K56-2,cystic fibrosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,O-oligosaccharyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24673753,PubMed,10.1111/mmi.12540,,jon.dennis@ualberta.ca,,K V Lithgow 2014,2014,1 gene,Lithgow-2014-A general protein O-,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5631,PHI:4129,UniProt,W6EL00,GenBank,AHJ11173,,,FB2,Tea4,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),subsp. mays cv. W23,,,leaf,critical determinant of the axis of polarized growth,,,,loss of pathogenicity,,,,,,,,aberrant,,no,Congo red; calcofluor white; sorbitol; thiabendazole,sorbitol: CHEBI:30911; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; thiabendazole: CHEBI:45979,,,,,gene deletion: full,,,RP,24613993,PubMed,10.1016/j.fgb.2014.02.010,,fbanuett@csulb.edu,"Mutants are defective in the stress response / Tea4 is essential for tumor induction in strains that bypass cell fusion (e.g., the solopathogenic strains) but is dis-pensable when cell fusion occurs.",M Valinluck 2014,2014,1 gene,Valinluck-2014-The cell end marker,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5632,PHI:4129,UniProt,W6EL00,GenBank,AHJ11173,,,FB2,Tea4,,,,,,,5270,Ustilago maydis,559306,FB1,smut,monocots,4577,Zea mays (related: maize),subsp. mexicana,,,leaf,critical determinant of the axis of polarized growth,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,Congo red; calcofluor white; sorbitol; thiabendazole,sorbitol: CHEBI:30911; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; thiabendazole: CHEBI:45979,,,,,gene deletion: full,,,RP,24613993,PubMed,10.1016/j.fgb.2014.02.010,,fbanuett@csulb.edu,"Mutants are defective in the stress response / Tea4 is essential for tumor induction in strains that bypass cell fusion (e.g., the solopathogenic strains) but is dis-pensable when cell fusion occurs.",M Valinluck 2014,2014,1 gene,Valinluck-2014-The cell end marker,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5633,PHI:4129,UniProt,W6EL00,GenBank,AHJ11173,,,FB2,Tea4,,,,,,,5270,Ustilago maydis,,FB2,smut,monocots,4577,Zea mays (related: maize),subsp. mexicana,,,leaf,critical determinant of the axis of polarized growth,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,Congo red; calcofluor white; sorbitol; thiabendazole,sorbitol: CHEBI:30911; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; thiabendazole: CHEBI:45979,,,,,gene deletion: full,,,RP,24613993,PubMed,10.1016/j.fgb.2014.02.010,,fbanuett@csulb.edu,"Mutants are defective in the stress response / Tea4 is essential for tumor induction in strains that bypass cell fusion (e.g., the solopathogenic strains) but is dis-pensable when cell fusion occurs.",M Valinluck 2014,2014,1 gene,Valinluck-2014-The cell end marker,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5634,PHI:4130,UniProt,A4VTV0,GenBank,ABF06562,,,31238,cps2J,,,,,,,1307,Streptococcus suis,286604,serotype 2 strain 89/1591,meningitis,,,,Lethal pathogen phenotype,,,,genes involved in side-chain formation,,,Wzx/Wzy- dependent pathway,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,24654559,PubMed,10.1111/1574-6968.12428,,asekizak@mail.ecc.u-tokyo.ac.jp,,N Lakkitjaroen,2014,4 genes,Lakkitjaroen-2014-Capsule loss or deat,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5635,PHI:4131,UniProt,M3ULC8,GenBank,BAM94471,,,2651,cps2N,,,,,,,1307,Streptococcus suis,286604,serotype 2 strain 89/1591,meningitis,,,,Lethal pathogen phenotype,,,,genes involved in side-chain formation,,,Wzx/Wzy- dependent pathway,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,24654559,PubMed,10.1111/1574-6968.12428,,asekizak@mail.ecc.u-tokyo.ac.jp,,N Lakkitjaroen,2014,4 genes,Lakkitjaroen-2014-Capsule loss or deat,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5636,PHI:4132,UniProt,C6GKH4,GenBank,ACT10302,,,,cps2I,,,,,,,1307,Streptococcus suis,286604,serotype 2 strain 89/1591,meningitis,,,,Lethal pathogen phenotype,,,,polymerase,,,Wzx/Wzy- dependent pathway,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,24654559,PubMed,10.1111/1574-6968.12428,,asekizak@mail.ecc.u-tokyo.ac.jp,,N Lakkitjaroen,2014,4 genes,Lakkitjaroen-2014-Capsule loss or deat,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5637,PHI:4133,UniProt,M3V795,GenBank,BAM94668,,,13730,cps2O,,,,,,,1307,Streptococcus suis,286604,serotype 2 strain 89/1591,meningitis,,,,Lethal pathogen phenotype,,,,flippase,,,Wzx/Wzy- dependent pathway,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,24654559,PubMed,10.1111/1574-6968.12428,,asekizak@mail.ecc.u-tokyo.ac.jp,,N Lakkitjaroen,2014,4 genes,Lakkitjaroen-2014-Capsule loss or deat,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5638,PHI:4134,UniProt,G7TKR3,GenBank,AEQ95769,,,BLS256,xrp1,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,leaf,required for full virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24675748,PubMed,10.1371/journal.pone.0093205,,gyouchen@sjtu.edu.cn,,X Xue 2014,2014,5 genes,Xue-2014-Identification of 17,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5639,PHI:4135,UniProt,G7TC28,GenBank,AEQ98641,,,BLS256,xrp2,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,leaf,required for full virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24675748,PubMed,10.1371/journal.pone.0093205,,gyouchen@sjtu.edu.cn,,X Xue 2014,2014,5 genes,Xue-2014-Identification of 17,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5640,PHI:4136,UniProt,G7TJY8,GenBank,AEQ95731,,,BLS256,xrp5,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24675748,PubMed,10.1371/journal.pone.0093205,,gyouchen@sjtu.edu.cn,,X Xue 2014,2014,5 genes,Xue-2014-Identification of 17,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5641,PHI:4137,UniProt,G7TG38,GenBank,AEQ96593,,,BLS256,xrp8,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24675748,PubMed,10.1371/journal.pone.0093205,,gyouchen@sjtu.edu.cn,,X Xue 2014,2014,5 genes,Xue-2014-Identification of 17,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5642,PHI:4138,UniProt,G7TIP9,GenBank,AEQ94342,,,BLS256,xrp14,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,leaf,required for full virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24675748,PubMed,10.1371/journal.pone.0093205,,gyouchen@sjtu.edu.cn,,X Xue 2014,2014,5 genes,Xue-2014-Identification of 17,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5643,PHI:4139,UniProt,Q839C1,GenBank,AAO80120,,,V583,ldh-1,,,,,,,1351,Enterococcus faecalis,226185,V583,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney,redox balance,,,,unaffected pathogenicity,,,,,,,,reduced,,no,DMSO; H2O2; hypochlorite; SDS; NaCl; glucose; ethanol,DMSO: CHEBI:28262; H2O2: CHEBI:16240; hypochlorite: CHEBI:29222; SDS: CHEBI:8984; NaCl: CHEBI:26710; glucose: CHEBI:17234; ethanol: CHEBI:16236,,,,,gene mutation; gene complementation,,,RP,23649090,PubMed,10.1128/IAI.01299-12,,axel.hartke@unicaen.fr,The growth performance of the ldh-2 mutants under most stress conditions was similar to that of the corresponding wild-type strains. ldh-1 mutants were more strss sensitive,N F Rana 2014,2014,2 genes,Rana-2013-Redox Balance via La,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5644,PHI:4140,UniProt,Q838C9,GenBank,AAO80466,,,V583,ldh-2,,,,,,,1351,Enterococcus faecalis,226185,V583,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney,redox balance,,,,unaffected pathogenicity,,,,,,,,wild type,,no,DMSO; H2O2; hypochlorite; SDS; NaCl; glucose; ethanol,DMSO: CHEBI:28262; H2O2: CHEBI:16240; hypochlorite: CHEBI:29222; SDS: CHEBI:8984; NaCl: CHEBI:26710; glucose: CHEBI:17234; ethanol: CHEBI:16236,,,,,gene mutation; gene complementation,,,RP,23649090,PubMed,10.1128/IAI.01299-12,,axel.hartke@unicaen.fr,The growth performance of the ldh-2 mutants under most stress conditions was similar to that of the corresponding wild-type strains. ldh-1 mutants were more strss sensitive,N F Rana 2014,2014,2 genes,Rana-2013-Redox Balance via La,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5645,PHI:4139,UniProt,Q839C1,GenBank,AAO80120,,,V583,ldh-1,,,,,,PHI:4140,1351,Enterococcus faecalis,226185,V583,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney,redox balance,,,,reduced virulence,,,,,,,,reduced,,no,DMSO; H2O2; hypochlorite; SDS; NaCl; glucose; ethanol,DMSO: CHEBI:28262; H2O2: CHEBI:16240; hypochlorite: CHEBI:29222; SDS: CHEBI:8984; NaCl: CHEBI:26710; glucose: CHEBI:17234; ethanol: CHEBI:16236,,,,,gene mutation; gene complementation,,,RP,23649090,PubMed,10.1128/IAI.01299-12,,axel.hartke@unicaen.fr,The growth performance of the ldh-2 mutants under most stress conditions was similar to that of the corresponding wild-type strains. ldh-1 mutants were more strss sensitive,N F Rana 2014,2014,2 genes,Rana-2013-Redox Balance via La,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5646,PHI:4140,UniProt,Q838C9,GenBank,AAO80466,,,V583,ldh-2,,,,,,PHI:4139,1351,Enterococcus faecalis,226185,V583,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney,redox balance,,,,reduced virulence,,,,,,,,reduced,,no,DMSO; H2O2; hypochlorite; SDS; NaCl; glucose; ethanol,DMSO: CHEBI:28262; H2O2: CHEBI:16240; hypochlorite: CHEBI:29222; SDS: CHEBI:8984; NaCl: CHEBI:26710; glucose: CHEBI:17234; ethanol: CHEBI:16236,,,,,gene mutation; gene complementation,,,RP,23649090,PubMed,10.1128/IAI.01299-12,,axel.hartke@unicaen.fr,The growth performance of the ldh-2 mutants under most stress conditions was similar to that of the corresponding wild-type strains. ldh-1 mutants were more strss sensitive,N F Rana 2014,2014,2 genes,Rana-2013-Redox Balance via La,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5647,PHI:4141,UniProt,Q73R77,GenBank,AAS10711,,,ATCC 35405,TDE0214,,,,,,,158,Treponema denticola,243275,ATCC 35405,periodontitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin; blood,"motility, biofilm formation, and virulence of the spirochete",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,23794624,PubMed,10.1128/JB.00610-13,,cli9@buffalo.edu,,J Bian 2014,2014,1 gene,Bian-2013-Inactivation of cycl,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5648,PHI:4142,UniProt,I1C4E4,GenBank,EIE83324,,,99-880,CotH2,,,,,,,64495,Rhizopus arrhizus,,99-880,mucormycosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung; brain,invasin,,,,reduced virulence,,,,,,,,,,no,Congo red; calcofluor white; hydrogen peroxide; SDS; triton X-100,"SDS: CHEBI:8984; congo red: CHEBI:34653; calcofluor   white,  H2O2: CHEBI:16240; Triton X-100: CHEBI:9750",,,,,altered gene expression / gene regulation: silencing,,,RP,24355926,PubMed,10.1172/JCI71349,,ibrahim@labiomed.org,CotH2 and CotH3 proteins are dispensable for cell wall composition and organization,T Gebremariam 2014,2014,2 genes,Gebremariam-2014-CotH3 mediates funga,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5649,PHI:4143,UniProt,I1CFE1,GenBank,EIE87171,,,99-880,CotH3,,,,,,,64495,Rhizopus arrhizus,,99-880,mucormycosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung; brain,invasin,,,,reduced virulence,,,,,,,,,,no,Congo red; calcofluor white; hydrogen peroxide; SDS; triton X-100,"SDS: CHEBI:8984; congo red: CHEBI:34653; calcofluor   white,  H2O2: CHEBI:16240; Triton X-100: CHEBI:9750",,,,,altered gene expression / gene regulation: silencing,,,RP,24355926,PubMed,10.1172/JCI71349,,ibrahim@labiomed.org,CotH2 and CotH3 proteins are dispensable for cell wall composition and organization,T Gebremariam 2014,2014,2 genes,Gebremariam-2014-CotH3 mediates funga,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5650,PHI:4144,UniProt,Q8PHN8,GenBank,AAM38055,,,306,ostA,,,,,,,346,Xanthomonas citri,611301,subsp. citri,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,leaf,trehalose-6-phosphate synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24676796,PubMed,10.1007/s10142-013-0340-5,,marcia@iq.ufrj.br,,A P Facincani 2014,2014,4 genes,Facincani-2014-Comparative proteomi,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5651,PHI:4145,UniProt,Q8PLR7,GenBank,AAM36589,,,306,XAC1722,,,,,,,346,Xanthomonas citri,611301,subsp. citri,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,leaf,"2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24676796,PubMed,10.1007/s10142-013-0340-5,,marcia@iq.ufrj.br,,A P Facincani 2014,2014,4 genes,Facincani-2014-Comparative proteomi,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5652,PHI:4146,UniProt,Q8PHE6,GenBank,AAM38154,,,306,XAC3311,,,,,,,346,Xanthomonas citri,611301,subsp. citri,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,leaf,"IroN, a TonB-dependent receptor",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24676796,PubMed,10.1007/s10142-013-0340-5,,marcia@iq.ufrj.br,,A P Facincani 2014,2014,4 genes,Facincani-2014-Comparative proteomi,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5653,PHI:4147,UniProt,Q8PN16,GenBank,AAM36129,,,306,XAC1258,,,,,,,346,Xanthomonas citri,611301,subsp. citri,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,leaf,"CyoA, cytochrome O ubiquinol oxidase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24676796,PubMed,10.1007/s10142-013-0340-5,,marcia@iq.ufrj.br,,A P Facincani 2014,2014,4 genes,Facincani-2014-Comparative proteomi,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5654,PHI:4148,UniProt,D4F368,GenBank,EFE23792,,,ATCC 23685,Ivy,,,,,,,636,Edwardsiella tarda,,TX01,,bony fishes,52904,Scophthalmus maximus (related: turbot),,,,blood; liver; kidney; spleen,inhibitor of vertebrate lysozyme,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23817616,PubMed,10.1128/IAI.00503-13,,lsun@qdio.ac.cn,,C Wang 2014,2014,1 gene,Wang-2013-Edwardsiella tarda I,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5655,PHI:4149,UniProt,D2TRX7,GenBank,CBG91572,,,ICC168,NleH,,,,,,,67825,Citrobacter rodentium,,DBS100,colonic hyperplasia (mouse),rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,colon,encodes type III effector,,,NF- kappa B,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24613200,PubMed,10.1016/j.micinf.2014.02.003,,hardwidg@gmail.com,,L A Feuerbacher 2014,2014,1 gene,Feuerbacher-2014-Influence of NleH ef,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5656,PHI:4149,UniProt,D2TRX7,GenBank,CBG91572,,,ICC168,NleH,,,,,,,67825,Citrobacter rodentium,,DBS100,colonic hyperplasia (mouse),rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,colon,encodes type III effector,,,NF- kappa B,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24613200,PubMed,10.1016/j.micinf.2014.02.003,,hardwidg@gmail.com,,L A Feuerbacher 2014,2014,1 gene,Feuerbacher-2014-Influence of NleH ef,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5657,PHI:4150,UniProt,Q3BDH0,GenBank,AAW65729,,,44276,LruA,,,,,,,173,Leptospira interrogans,214675,serovar Manilae strain L495,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,kidney,lipoprotein that has been implicated in leptospiral uveitis as a target of the immune response,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23918777,PubMed,10.1128/IAI.01195-12,,ben.adler@monash.edu,,K Zhang 2014,2014,1 gene,Zhang-2013-Leptospiral LruA is,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5658,PHI:4151,UniProt,Q4TVQ0,GenBank,AAY54617,,,10403S,PrfA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; liver; spleen,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,24667708,PubMed,10.1128/mBio.00969-14,,pcossart@pasteur.fr,,C Bécavin 2014,2014,1 gene,Becavin-2014-Comparison of Widely,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5659,PHI:4151,UniProt,Q4TVQ0,GenBank,AAY54617,,,10403S,PrfA,,,,,,,1639,Listeria monocytogenes,393133,10403S,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; liver; spleen,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,24667708,PubMed,10.1128/mBio.00969-14,,pcossart@pasteur.fr,,C Bécavin 2014,2014,1 gene,Becavin-2014-Comparison of Widely,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5660,PHI:4151,UniProt,Q4TVQ0,GenBank,AAY54617,,,10403S,PrfA,,,,,,,1639,Listeria monocytogenes,1334565,EGD,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; liver; spleen,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,24667708,PubMed,10.1128/mBio.00969-14,,pcossart@pasteur.fr,,C Bécavin 2014,2014,1 gene,Becavin-2014-Comparison of Widely,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5661,PHI:4152,UniProt,Q03023,GenBank,CAA45858,,,PAO1,aprA,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,alkaline protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24654978,PubMed,10.1094/MPMI-02-14-0032-R,,Pieterse@uu.nl,,M J C Pel 2014,2014,1 gene,Pel-2014-Pseudomonas syringae,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5662,PHI:4152,UniProt,Q03023,GenBank,CAA45858,,,PAO1,aprA,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,alkaline protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24654978,PubMed,10.1094/MPMI-02-14-0032-R,,Pieterse@uu.nl,,M J C Pel 2014,2014,1 gene,Pel-2014-Pseudomonas syringae,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5663,PHI:4153,,no data found,,,,,,HopZ4,,,,,,,317,Pseudomonas syringae,629260,pv. lachrymans strain M301315,angular leaf spot (cucumber),eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,YopJ superfamily effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24625030,PubMed,10.1094/MPMI-12-13-0363-R,,uestuen@igzev.de,,S Üstün 2014,2014,1 gene,Ustun-2014-HopZ4 from Pseudomon,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5664,PHI:4154,UniProt,A0Q7H2,GenBank,ABK90187,,,U112,IglE,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"IglE lipidation is required for outer membrane localization, intramacrophage replication, and virulence in mice",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24616435,PubMed,10.1111/2049-632X.12167,,Karl.Klose@utsa.edu,,J Nguyen 2014,2014,1 gene,Nguyen-2014-Lipidation of the FP,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5665,PHI:4155,UniProt,R9RJ65,GenBank,AGM49306,,,SS2-1,stk,,,,,,,1307,Streptococcus suis,,serotype 2,meningitis,even-toed ungulates,9823,Sus scrofa (related: pig),,,,,eukaryotic-type serine/threonine kinases,,,,reduced virulence,,,,,,,,reduced,,no,HCl; H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710; HCl: CHEBI:17883,,,,,gene deletion: full; gene complementation,,,RP,24637959,PubMed,10.1371/journal.pone.0091971,,kwh2003@263.net,"The stk deletion mutants exhibited a notable reduced tolerance of environmental stresses including high temperature, acidic pH, oxidative stress, and high osmolarity.",H Zhu 2014,2014,1 gene,Zhu-2014-Contribution of Euka,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5666,PHI:4155,UniProt,R9RJ65,GenBank,AGM49306,,,SS2-1,stk,,,,,,,1307,Streptococcus suis,,serotype 2,meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen; kidney; brain; blood,eukaryotic-type serine/threonine kinases,,,,reduced virulence,,,,,,,,reduced,,no,HCl; H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710; HCl: CHEBI:17883,,,,,gene deletion: full; gene complementation,,,RP,24637959,PubMed,10.1371/journal.pone.0091971,,kwh2003@263.net,"The stk deletion mutants exhibited a notable reduced tolerance of environmental stresses including high temperature, acidic pH, oxidative stress, and high osmolarity.",H Zhu 2014,2014,1 gene,Zhu-2014-Contribution of Euka,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5667,PHI:4156,,no data found,GenBank,BAH64287,,,NTUH-K2044,wcaK2,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,capsule polysaccharide,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5668,PHI:4157,,no data found,,,,,,pmrF,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,required for the synthesis and addition of amino-arabinose to lipid A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5669,PHI:4158,,no data found,,,,,,pagPGB,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5670,PHI:4159,UniProt,W0XKM3,GenBank,CDI16159,,,T69,lpxO,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,enzyme responsible for the 2-hydroxyacyl-modified lipid A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5671,PHI:4160,UniProt,B5XY48,GenBank,ACI08342,,,342,OmpA2,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,outer membrane proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5672,PHI:4161,UniProt,D6QLX8,GenBank,ADG56549,,,KP398/08,OmpK36,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,outer membrane proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5673,PHI:4162,UniProt,B5XSN9,GenBank,ACI11151,,,342,phoQ,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,govern the expression of cps and of the loci implicated in lipid A remodeling,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5674,PHI:4163,,no data found,,,,,,pmrAB,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,govern the expression of cps and of the loci implicated in lipid A remodeling,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5675,PHI:4164,UniProt,Q8GM84,GenBank,AAL25250,,,5055,rcsB,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,govern the expression of cps and of the loci implicated in lipid A remodeling,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5676,PHI:4157,,no data found,,,,,,pmrF,,,,,,PHI:4158,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5677,PHI:4158,,no data found,,,,,,pagPGB,,,,,,PHI:4157,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5678,PHI:4162,UniProt,B5XSN9,GenBank,ACI11151,,,342,phoQ,,,,,,PHI:4163,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,govern the expression of cps and of the loci implicated in lipid A remodeling,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5679,PHI:4163,,no data found,,,,,,pmrAB,,,,,,PHI:4162,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,govern the expression of cps and of the loci implicated in lipid A remodeling,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23836821,PubMed,10.1128/IAI.00391-13,,bengoechea@caubet-cimera.es,,J L Insua 2014,2014,9 genes,Insua-2013-Modeling Klebsiella,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5680,PHI:4165,UniProt,M1RXP4,GenBank,AGG35485,,,P131,ALG3,,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,"encodes an a-1,3-mannosyltransferase for protein N-glycosylation of effectors",,,,reduced virulence,,no,no,yes,smaller blast lesions,wild type,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,24642938,PubMed,10.1105/tpc.114.123588,,pengyl@cau.edu.cn,,X Chen 2014,2014,1 gene,Chen-2014-N-Glycosylation of E,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5681,PHI:4165,UniProt,M1RXP4,GenBank,AGG35485,,,P131,ALG3,,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,"encodes an a-1,3-mannosyltransferase for protein N-glycosylation of effectors",,,,reduced virulence,,no,no,yes,smaller blast lesions,wild type,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,24642938,PubMed,10.1105/tpc.114.123588,,pengyl@cau.edu.cn,,X Chen 2014,2014,1 gene,Chen-2014-N-Glycosylation of E,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5682,PHI:4166,UniProt,C3LQZ4,GenBank,ACP06672,,,M66-2,relA,,,,,,,666,Vibrio cholerae,345073,O395,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,CT production,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,24648517,PubMed,10.1074/jbc.M113.540088,,sangsun_yoon@yuhs.ac,,Y T Oh 2014,2014,4 genes,Oh-2014-Cholera toxin produc,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5683,PHI:4167,UniProt,Q9KNM2,GenBank,AAF95850,,,N16961,spoT,chromosome I,,,,,,666,Vibrio cholerae,345073,O395,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,CT production,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,24648517,PubMed,10.1074/jbc.M113.540088,,sangsun_yoon@yuhs.ac,,Y T Oh 2014,2014,4 genes,Oh-2014-Cholera toxin produc,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5684,PHI:4168,UniProt,Q9KSN2,GenBank,AAF94383,,,N16961,relV,,,,,,,666,Vibrio cholerae,345073,O395,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,CT production,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,24648517,PubMed,10.1074/jbc.M113.540088,,sangsun_yoon@yuhs.ac,,Y T Oh 2014,2014,4 genes,Oh-2014-Cholera toxin produc,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5685,PHI:4169,UniProt,G7TTE0,GenBank,AET25621,,,2010EL-1786,dksA,,,,,,,666,Vibrio cholerae,345073,O395,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,CT production,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,24648517,PubMed,10.1074/jbc.M113.540088,,sangsun_yoon@yuhs.ac,,Y T Oh 2014,2014,4 genes,Oh-2014-Cholera toxin produc,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5686,PHI:4166,UniProt,C3LQZ4,GenBank,ACP06672,,,M66-2,relA,,,,,,PHI:4167,666,Vibrio cholerae,345073,O395,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,CT production,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,24648517,PubMed,10.1074/jbc.M113.540088,,sangsun_yoon@yuhs.ac,,Y T Oh 2014,2014,4 genes,Oh-2014-Cholera toxin produc,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5687,PHI:4167,UniProt,Q9KNM2,GenBank,AAF95850,,,N16961,spoT,chromosome I,,,,,PHI:4166,666,Vibrio cholerae,345073,O395,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,CT production,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,24648517,PubMed,10.1074/jbc.M113.540088,,sangsun_yoon@yuhs.ac,,Y T Oh 2014,2014,4 genes,Oh-2014-Cholera toxin produc,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5688,PHI:4169,UniProt,E5ADK1,GenBank,CBY01290,,,JN3,LmSNF1,,,,,,,5022,Leptosphaeria maculans,,IBCN 14,stem canker,eudicots,3708,Brassica napus (related: rape),cv. Westar,,,cotyledon,repression and derepression of the cell wall degrading enzymes,,,,loss of pathogenicity,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full,,,RP,24638039,PubMed,10.1371/journal.pone.0092503,,sheau-fang.hwang@gov.ab.ca,,J Feng 2014,2014,1 gene,Feng-2014-The LmSNF1 Gene Is R,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5689,PHI:4170,UniProt,D7HX71,GenBank,EFI00478,,,NCPPB 3335,iaaM-1,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),,,,stem,biosynthesis of IAA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24606017,PubMed,10.1111/1574-6968.12413,,iperezm@uma.es,,I M Aragon 2014,2014,4 genes,Aragon-2014-New insights into th,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5690,PHI:4171,UniProt,P06618,GenBank,AAA25853,,,,iaaH-1,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),,,,stem,biosynthesis of IAA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24606017,PubMed,10.1111/1574-6968.12413,,iperezm@uma.es,,I M Aragon 2014,2014,4 genes,Aragon-2014-New insights into th,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5691,PHI:4172,,no data found,,,,,,iaaM-2,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),,,,stem,biosynthesis of IAA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24606017,PubMed,10.1111/1574-6968.12413,,iperezm@uma.es,,I M Aragon 2014,2014,4 genes,Aragon-2014-New insights into th,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5692,PHI:4173,,no data found,,,,,,iaaH-2,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),,,,stem,biosynthesis of IAA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24606017,PubMed,10.1111/1574-6968.12413,,iperezm@uma.es,,I M Aragon 2014,2014,4 genes,Aragon-2014-New insights into th,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5693,PHI:4174,UniProt,A0A098D2Y5,EMBL,FGRAMPH1_01T03055,,,PH-1,Fgac1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,adenylyl cyclase,,,cAMP pathway,reduced virulence,,yes,yes,,,increased,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,24603887,PubMed,10.1371/journal.pone.0091135,,bormann j@botanik.un i-hamburg.de,abundant sporulation on wheat epidermis,J Bormann 2014,2014,1 gene,Bormann-2014-The Adenylyl Cyclase,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5694,PHI:4174,UniProt,A0A098D2Y5,EMBL,FGRAMPH1_01T03055,,,PH-1,Fgac1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. A188,,,cob,adenylyl cyclase,,,cAMP pathway,unaffected pathogenicity,,yes,yes,,,increased,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,24603887,PubMed,10.1371/journal.pone.0091135,,bormann j@botanik.un i-hamburg.de,abundant sporulation on wheat epidermis,J Bormann 2014,2014,1 gene,Bormann-2014-The Adenylyl Cyclase,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5695,PHI:4175,UniProt,U6ZHA8,GenBank,ERO57666,,,D s0432-1,kdgR,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,virulence negative regulators,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene mutation,,,RP,24625032,PubMed,10.1094/MPMI-09-13-0270-R,,lojkowska@biotech.ug.gda.pl,,M Potrykus 2014,2014,5 genes,Potrykus-2014-Regulators involved,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5696,PHI:4176,UniProt,U6ZIA1,GenBank,ERO59123,,,D s0432-1,pecS,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,virulence negative regulators,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24625032,PubMed,10.1094/MPMI-09-13-0270-R,,lojkowska@biotech.ug.gda.pl,,M Potrykus 2014,2014,5 genes,Potrykus-2014-Regulators involved,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5697,PHI:4176,UniProt,U6ZIA1,GenBank,ERO59123,,,D s0432-1,pecS,,,,,,,1089444,Dickeya solani,,IFB0158,soft rot,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,virulence negative regulators,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24625032,PubMed,10.1094/MPMI-09-13-0270-R,,lojkowska@biotech.ug.gda.pl,,M Potrykus 2014,2014,5 genes,Potrykus-2014-Regulators involved,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5698,PHI:4177,UniProt,U6ZEP7,GenBank,ERO57687,,,D s0432-1,pecT,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,virulence negative regulators,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24625032,PubMed,10.1094/MPMI-09-13-0270-R,,lojkowska@biotech.ug.gda.pl,,M Potrykus 2014,2014,5 genes,Potrykus-2014-Regulators involved,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5699,PHI:4178,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,expR,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,synthesis and perception of signaling molecules,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24625032,PubMed,10.1094/MPMI-09-13-0270-R,,lojkowska@biotech.ug.gda.pl,,M Potrykus 2014,2014,5 genes,Potrykus-2014-Regulators involved,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5700,PHI:4179,UniProt,U6ZHS1,GenBank,ERO58913,,,D s0432-1,expI,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,synthesis and perception of signaling molecules,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24625032,PubMed,10.1094/MPMI-09-13-0270-R,,lojkowska@biotech.ug.gda.pl,,M Potrykus 2014,2014,5 genes,Potrykus-2014-Regulators involved,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5701,PHI:4180,UniProt,C1CHE9,GenBank,ACO18572,,,JJA,arcD,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,arginine deiminase system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,2391877,PubMed,10.1128/IAI.00778-13,,baig@mail.amc.edu,,R Gupta 2014,2014,2 genes,Gupta-2013-Deletion of arcD in,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5702,PHI:4181,UniProt,J1B9B1,GenBank,EJH18560,,,GA58981,arcT,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,arginine deiminase system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,2391877,PubMed,10.1128/IAI.00778-13,,baig@mail.amc.edu,,R Gupta 2014,2014,2 genes,Gupta-2013-Deletion of arcD in,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5703,PHI:4182,UniProt,A0AUJ1,GenBank,AAX94565,,,,Gib2,,,,,,,5207,Cryptococcus neoformans,235443,H99,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,brain,scaffolding protein promoting cAMP signaling,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,24659785,PubMed,10.1074/jbc.M113.537183,,pwang@lsuhsc.edu,,Y Wang 2014,2014,1 gene,Wang-2014-Noncanonical Gbeta G,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5704,PHI:4183,UniProt,Q7ARB8,GenBank,AAC82740,,,KIM10+,"ypmt1,66c",,,,,,,632,Yersinia pestis,214092,CO92,bubonic plague,rodents,10090,Mus musculus (related: house mouse),OF1,,,lymph node; spleen,putative DNA binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,24675805,PubMed,10.1371/journal.ppat.1004029,,florent.sebbane@inserm.fr,,E Pradel 2014,2014,7 genes,Pradel-2014-New Insights into Ho,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5705,PHI:4183,UniProt,Q7ARB8,GenBank,AAC82740,,,KIM10+,"ypmt1,66c",,,,,,,632,Yersinia pestis,214092,CO92,bubonic plague,rodents,10090,Mus musculus (related: house mouse),,,,lymph node; spleen,putative DNA binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,24675805,PubMed,10.1371/journal.ppat.1004029,,florent.sebbane@inserm.fr,,E Pradel 2014,2014,7 genes,Pradel-2014-New Insights into Ho,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5706,PHI:4184,UniProt,Q74QL4,GenBank,AAS63610,,,91001,ypo0988,,,,,,,632,Yersinia pestis,214092,CO92,bubonic plague,rodents,10090,Mus musculus (related: house mouse),OF1,,,lymph node; spleen,putative DNA binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,24675805,PubMed,10.1371/journal.ppat.1004029,,florent.sebbane@inserm.fr,,E Pradel 2014,2014,7 genes,Pradel-2014-New Insights into Ho,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5707,PHI:4185,UniProt,Q0WF94,GenBank,CAL20697,,,CO92,ypo2062,,,,,,,632,Yersinia pestis,214092,CO92,bubonic plague,rodents,10090,Mus musculus (related: house mouse),OF1,,,lymph node; spleen,putative DNA binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,24675805,PubMed,10.1371/journal.ppat.1004029,,florent.sebbane@inserm.fr,,E Pradel 2014,2014,7 genes,Pradel-2014-New Insights into Ho,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5708,PHI:4186,UniProt,Q7CGG8,GenBank,AAM87070,,,AE013955_4,ypo0656,,,,,,,632,Yersinia pestis,214092,CO92,bubonic plague,rodents,10090,Mus musculus (related: house mouse),OF1,,,lymph node; spleen,putative DNA binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,24675805,PubMed,10.1371/journal.ppat.1004029,,florent.sebbane@inserm.fr,,E Pradel 2014,2014,7 genes,Pradel-2014-New Insights into Ho,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5709,PHI:4187,UniProt,Q74T23,GenBank,AAS62576,,,91001,ypo2560-61,,,,,,,632,Yersinia pestis,214092,CO92,bubonic plague,rodents,10090,Mus musculus (related: house mouse),OF1,,,lymph node; spleen,putative DNA binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,24675805,PubMed,10.1371/journal.ppat.1004029,,florent.sebbane@inserm.fr,,E Pradel 2014,2014,7 genes,Pradel-2014-New Insights into Ho,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5710,PHI:4188,UniProt,Q0WBS6,GenBank,CAL21958,,,CO92,ypo3369,,,,,,,632,Yersinia pestis,214092,CO92,bubonic plague,rodents,10090,Mus musculus (related: house mouse),OF1,,,lymph node; spleen,putative DNA binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,24675805,PubMed,10.1371/journal.ppat.1004029,,florent.sebbane@inserm.fr,,E Pradel 2014,2014,7 genes,Pradel-2014-New Insights into Ho,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5711,PHI:4189,UniProt,Q7CG15,GenBank,AE013987_5,,,KIM10+,ypo3991,,,,,,,632,Yersinia pestis,214092,CO92,bubonic plague,rodents,10090,Mus musculus (related: house mouse),OF1,,,lymph node; spleen,putative DNA binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,RP,24675805,PubMed,10.1371/journal.ppat.1004029,,florent.sebbane@inserm.fr,,E Pradel 2014,2014,7 genes,Pradel-2014-New Insights into Ho,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5712,PHI:4190,UniProt,Q8YIE6,GenBank,AAL51679,,,16M,cspA,,,,,,,29459,Brucella melitensis,1029825,NI,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,cold shock protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24661136,PubMed,10.1111/1574-6968.12430,,wuqm@cau.edu.cn,Mutant showed an increased sensitivity to acidic and H2O2 stresses and slower growth at 15 degrees C.,Z Wang 2014,2014,1 gene,Wang-2014-Cold Shock Protein A,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5713,PHI:4191,UniProt,Q33BM7,GenBank,BAE48276,,,UP-MMC,LipL41,,,,,,,173,Leptospira interrogans,214675,serovar Manilae strain L495,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,kidney,leptospiral outer membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23690405,PubMed,10.1128/IAI.00531-13,,ben.adler@monash.edu,,A M King 2014,2014,2 genes,King-2013-Leptospiral outer me,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5714,PHI:4192,UniProt,Q8F8E2,GenBank,AAN47814,,,56601,Lep,,,,,,,173,Leptospira interrogans,214675,serovar Manilae strain L495,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,kidney,small chaperone protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,23690405,PubMed,10.1128/IAI.00531-13,,ben.adler@monash.edu,,A M King 2014,2014,2 genes,King-2013-Leptospiral outer me,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5715,PHI:4193,UniProt,Q5AL16,GenBank,EAL03398,,,SC5314,STP2,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,A transcription factor that regulates the expression of multiple amino acid permeases.,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,24626429,PubMed,10.1371/journal.ppat.1003995,,Michael.Lorenz@uth.tmc.edu,,S Vylkova 2014,2014,1 gene,Vylkova-2014-Modulation of Phagos,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5716,PHI:4194,UniProt,V5XZS6,GenBank,BAO10618,,,15A,AKT7,,,,,,,5599,Alternaria alternata,,ATCC 90610,black rot (Citrus),eudicots,3767,Pyrus pyrifolia (related: sha li),cv. Nijisseiki,,,leaf,encodes a cytochrome P450 monooxygenase and functions to limit AK-toxin production,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24611558,PubMed,10.1111/nph.12754,,ttsuge@agr.nagoya-u.ac.jp,,S Takaoka 2014,2014,1 gene,Takaoka-2014-Complex regulation o,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5717,PHI:4194,UniProt,V5XZS6,GenBank,BAO10618,,,15A,AKT7,,,,,,,5599,Alternaria alternata,,ATCC 90610,black rot (Citrus),eudicots,3747,Fragaria x ananassa (related: strawberry),cv. Morioka,,,leaf,encodes a cytochrome P450 monooxygenase and functions to limit AK-toxin production,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,24611558,PubMed,10.1111/nph.12754,,ttsuge@agr.nagoya-u.ac.jp,,S Takaoka 2014,2014,1 gene,Takaoka-2014-Complex regulation o,Batch037,2014-04-01,MC,,,,,,,,,,,,,
,,Record 5718,PHI:4195,UniProt,Q63KH5,GenBank,CAH38859,,,K96243,BPSS1385,chromosome 2,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,,cell cycle-inhibiting factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24809950,PubMed,10.1371/journal.pone.0096298,,sunee.kor@mahidol.ac.th,,P Pumirat 2014,2014,1 gene,"Pumirat-2014-Analysis of the Prevalence, Secre",Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5719,PHI:4195,UniProt,Q63KH5,GenBank,CAH38859,,,K96243,BPSS1385,chromosome 2,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),U-937 cell line,,,,cell cycle-inhibiting factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24809950,PubMed,10.1371/journal.pone.0096298,,sunee.kor@mahidol.ac.th,,P Pumirat 2014,2014,1 gene,"Pumirat-2014-Analysis of the Prevalence, Secre",Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5720,PHI:4196,UniProt,P9WQD6,GenBank,AAK46590,,,CDC1551,KasB,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; liver,a crucial mycolic acid biosynthetic enzyme,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24809459,PubMed,10.1371/journal.ppat.1004115,,laurent.kremer@univ-montp2.fr,,C Vilchèze 2014,2014,1 gene,Vilcheze-2014-Phosphorylation of KasB Regulate,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5721,PHI:4196,UniProt,P9WQD6,GenBank,AAK46590,,,CDC1551,KasB,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,lung; spleen; liver,a crucial mycolic acid biosynthetic enzyme,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24809459,PubMed,10.1371/journal.ppat.1004115,,laurent.kremer@univ-montp2.fr,,C Vilchèze 2014,2014,1 gene,Vilcheze-2014-Phosphorylation of KasB Regulate,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5722,PHI:4197,UniProt,Q5KAG0,GenBank,AAW45840,,,JEC21,LHC1,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,brain,secreted lactonohydrolase involved in altering the capsular polysaccharide,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24789368,PubMed,10.1371/journal.ppat.1004037,,williamsonpr@mail.nih.gov,,Y Park 2014,2014,1 gene,Park-2014-A Role for LHC1 in Higher Order Stru,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5723,PHI:4198,UniProt,B3VA60,GenBank,ACE75886,,,H292,CovR,,,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,group A streptococcal infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serves to repress GAS virulence factor-encoding genes,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,24788524,PubMed,10.1371/journal.ppat.1004088,,sshelburne@mdanderson.org,,N Horstmann 2014,2014,1 gene,Horstmann-2014-Dual-site phosphorylation of th,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5724,PHI:4199,UniProt,R4VQG3,GenBank,AGM98470,,,SF1,Sil,,,,,,,1346,Streptococcus iniae,1318633,SF1,meningoencephalitis,bony fishes,52904,Scophthalmus maximus (related: turbot),,,,kidney; spleen,putative bacteriocin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence,,,RP,24781647,PubMed,10.1371/journal.pone.0096222,,lsun@qdio.ac.cn,other evidence: pretreatment with recombinant rsil prior to infection with the pathogen,M Li 2014,2014,1 gene,Li-2014-Sil_ A Streptococcus iniae Bacteriocin,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5725,PHI:4200,UniProt,W0WL00,GenBank,CDH72532,,,MH38,gacS,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,cystic fibrosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,encoding an essential regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24780952,PubMed,10.1371/journal.pone.0095936,,sylvie.elsen@cea.fr,,K M Sall 2014,2014,1 gene,Sall-2014-A gacS Deletion in Pseudomonas aerug,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5726,PHI:4201,UniProt,D0N0J7,GenBank,EEY67160,,,T30-4,SFI1,,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,putative RXLR effector genes,,,MAP kinase cascades,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24763622,PubMed,10.1371/journal.ppat.1004057,,Paul.Birch@hutton.ac.uk; frederic.brunner@zmbp.uni-tuebingen.de,,X Zheng 2014,2014,7 genes,Zheng-2014-Functionally redundant RXLR effecto,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5727,PHI:4202,UniProt,D0N6D2,GenBank,EEY70623,,,T30-4,SFI3,,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,putative RXLR effector genes,,,MAP kinase cascades,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24763622,PubMed,10.1371/journal.ppat.1004057,,Paul.Birch@hutton.ac.uk; frederic.brunner@zmbp.uni-tuebingen.de,,X Zheng 2014,2014,7 genes,Zheng-2014-Functionally redundant RXLR effecto,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5728,PHI:4203,UniProt,D0NCC1,GenBank,EEY55635,,,T30-4,SFI4,,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,putative RXLR effector genes,,,MAP kinase cascades,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24763622,PubMed,10.1371/journal.ppat.1004057,,Paul.Birch@hutton.ac.uk; frederic.brunner@zmbp.uni-tuebingen.de,,X Zheng 2014,2014,7 genes,Zheng-2014-Functionally redundant RXLR effecto,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5729,PHI:4204,UniProt,D0NMF6,GenBank,EEY60877,,,T30-4,SFI5,,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,putative RXLR effector genes,,,MAP kinase cascades,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24763622,PubMed,10.1371/journal.ppat.1004057,,Paul.Birch@hutton.ac.uk; frederic.brunner@zmbp.uni-tuebingen.de,,X Zheng 2014,2014,7 genes,Zheng-2014-Functionally redundant RXLR effecto,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5730,PHI:4205,UniProt,D0NN72,GenBank,EEY61979,,,T30-4,SFI6,,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,putative RXLR effector genes,,,MAP kinase cascades,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24763622,PubMed,10.1371/journal.ppat.1004057,,Paul.Birch@hutton.ac.uk; frederic.brunner@zmbp.uni-tuebingen.de,,X Zheng 2014,2014,7 genes,Zheng-2014-Functionally redundant RXLR effecto,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5731,PHI:4206,UniProt,D0NXM3,GenBank,EEY67823,,,T30-4,SFI7,,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,putative RXLR effector genes,,,MAP kinase cascades,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24763622,PubMed,10.1371/journal.ppat.1004057,,Paul.Birch@hutton.ac.uk; frederic.brunner@zmbp.uni-tuebingen.de,,X Zheng 2014,2014,7 genes,Zheng-2014-Functionally redundant RXLR effecto,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5732,PHI:4207,UniProt,D0P1B2,GenBank,EEY54138,,,T30-4,SFI8,,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,putative RXLR effector genes,,,MAP kinase cascades,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24763622,PubMed,10.1371/journal.ppat.1004057,,Paul.Birch@hutton.ac.uk; frederic.brunner@zmbp.uni-tuebingen.de,,X Zheng 2014,2014,7 genes,Zheng-2014-Functionally redundant RXLR effecto,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5733,PHI:4208,UniProt,Q5A2B9,GenBank,EAK96845,,,SC5314,SPT20,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,transcription co-activator SPT20,,,,reduced virulence,,,,,,,,aberrant,,no,fluconazole; amphotericin B; 5-fluorocytosine; caspofungin; SDS; NaCl,"SDS: CHEBI:8984; NaCl: CHEBI:26710; fluconazole: CHEBI:46081, CAS:86386-73-4; amphotericin B: CHEBI:2682; 5-fluorocytosine: CHEBI:5100; caspofungin: CHEBI:474180",,,,,gene disruption; gene complementation,,,RP,24732310,PubMed,10.1371/journal.pone.0094468,,nfyytxj@gmail.com; emylonakis@lifespan.org,"the disruption of SPT20 affected C. albicans stress responses and suggests that SPT20 plays a role in maintaining cell wall integrity / mutant was hypersensitive to amphotericin B, fluconazole and caspofungin compared to the wild-type and spt20delta/SPT20 re-integrated strains",X Tan 2014,2014,1 gene,Tan-2014-The Role of Candida albicans SPT20 in,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5734,PHI:4208,UniProt,Q5A2B9,GenBank,EAK96845,,,SC5314,SPT20,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,transcription co-activator SPT20,,,,reduced virulence,,,,,,,,aberrant,,no,fluconazole; amphotericin B; 5-fluorocytosine; caspofungin; SDS; NaCl,"SDS: CHEBI:8984; NaCl: CHEBI:26710; fluconazole: CHEBI:46081, CAS:86386-73-4; amphotericin B: CHEBI:2682; 5-fluorocytosine: CHEBI:5100; caspofungin: CHEBI:474180",,,,,gene disruption; gene complementation,,,RP,24732310,PubMed,10.1371/journal.pone.0094468,,nfyytxj@gmail.com; emylonakis@lifespan.org,"the disruption of SPT20 affected C. albicans stress responses and suggests that SPT20 plays a role in maintaining cell wall integrity / mutant was hypersensitive to amphotericin B, fluconazole and caspofungin compared to the wild-type and spt20delta/SPT20 re-integrated strains",X Tan 2014,2014,1 gene,Tan-2014-The Role of Candida albicans SPT20 in,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5735,PHI:4208,UniProt,Q5A2B9,GenBank,EAK96845,,,SC5314,SPT20,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,transcription co-activator SPT20,,,,reduced virulence,,,,,,,,aberrant,,no,fluconazole; amphotericin B; 5-fluorocytosine; caspofungin; SDS; NaCl,"SDS: CHEBI:8984; NaCl: CHEBI:26710; fluconazole: CHEBI:46081, CAS:86386-73-4; amphotericin B: CHEBI:2682; 5-fluorocytosine: CHEBI:5100; caspofungin: CHEBI:474180",,,,,gene disruption; gene complementation,,,RP,24732310,PubMed,10.1371/journal.pone.0094468,,nfyytxj@gmail.com; emylonakis@lifespan.org,"the disruption of SPT20 affected C. albicans stress responses and suggests that SPT20 plays a role in maintaining cell wall integrity / mutant was hypersensitive to amphotericin B, fluconazole and caspofungin compared to the wild-type and spt20delta/SPT20 re-integrated strains",X Tan 2014,2014,1 gene,Tan-2014-The Role of Candida albicans SPT20 in,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5736,PHI:4209,UniProt,I1RA07,GenBank,ESU05488,,,PH-1,MYT3,,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,encodes a putative Myb-like transcription factor; a transcriptional regulator,,,,reduced virulence,yes,,,,,reduced,,reduced,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,24722578,PubMed,10.1371/journal.pone.0094359,,lee2443@snu.ac.kr,,Y Kim 2014,2014,1 gene,free text on pubmed,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5737,PHI:4210,UniProt,A5IXL1,GenBank,CAL58770,,,PG2,nifS,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,agalactia syndrome,even-toed ungulates,9940,Ovis aries (related: sheep),Lacaune,,,lymph node; mammary gland,nitrogen fixation protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24699671,PubMed,10.1371/journal.pone.0093970,,c.citti@envt.fr,,E Baranowski 2014,2014,1 gene,Baranowski-2014-Experimental infections with M,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5738,PHI:4211,UniProt,J9VNH2,GenBank,AFR95808,,,H99,FRE3,,,,,,,5207,Cryptococcus neoformans,235443,H99,,rodents,10090,Mus musculus (related: house mouse),Swiss albino,,,brain,iron reductase activity and to play a role in iron-dependent growth,,,,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,24692633,PubMed,10.1128/mBio.00941-14,,williamsonpr@mail.nih.gov,,G Hu 2014,2014,1 gene,Hu-2014-Microevolution during serial mouse pas,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5739,PHI:4212,UniProt,Q6WER3,GenBank,AAQ23181,,,,FGL1,,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,effector lipase,,,,reduced virulence,,no,no,yes,,,,,,no,linoleic acid; alpha-linolenic acid; 2-deoxy-d-glucose,linoleic acid: CHEBI:17351; alpha-linolenic acid: CHEBI:27432; 2-deoxy-d-glucose: CHEBI:15866,,,,,gene disruption,,,RP,24686113,PubMed,10.1104/pp.114.236737,,christian.voigt@uni-hamburg.de,FFAs not only inhibited plant callose biosynthesis in vitro and in planta but also partially restored virulence to the deltafgl1 mutant when applied during infection of wheat spikelets,A Blümke 2014,2014,1 gene,Blumke-2014-Secreted Fungal Effector Lipase Re,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5740,PHI:4213,UniProt,P52988,GenBank,CAA53693,,,NCTC 10460,yenI,,,,,,,562,Escherichia coli,83334,serotype O157:H7 strain 86-24,,even-toed ungulates,9913,Bos taurus (related: cattle),Holstein Friesian,,,rectum,acyl-homoserine-lactone synthase,,,,unaffected pathogenicity,,,,,fewer lesions; colonization similar to the wild type strains,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23980115,PubMed,10.1128/IAI.00889-13,,vanessa.sperandio@utsouthwestern.edu,"Yersinia enterocolitica AHL synthase gene yenI was expressed in EHEC, Although the yenI EHEC colonized the Recto anal junction with efficiency equal to that of the WT, there was a trend for the cattle to shed the WT strain longer than the yenI EHEC.",Y N Nguyen 2013,2013,1 gene,Nguyen-2013-The acyl-homoserine lactone syntha,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5741,PHI:4214,UniProt,C5VV31,GenBank,CAR45292,,,P1/7,SSU0587,,,,,,,1307,Streptococcus suis,,JX081101,meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; kidney; liver; spleen,beta-galactosidase activity,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24670993,PubMed,10.1292/jvms.13-0625,,tangyulong@isa.ac.cn,,Y Tang,2014,1 gene,Tang-2014-Streptococcus suis Type 2 SSU0587 Pr,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5742,PHI:4215,UniProt,Q5NED6,GenBank,CAG45979,,,SCHU S4,IglE,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,lung; spleen; liver,outer membrane-associated lipoprotein essential for intracellular survival and murine virulence,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23959721,PubMed,10.1128/IAI.00595-13,,Michael.Norgard@UTSouthwestern.edu,,G T Robertson 2013,2013,1 gene,Robertson-2013-IglE is an outer membrane-assoc,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5743,PHI:4216,UniProt,E3QKK8,GenBank,EFQ31396,,,M1.001,SID1,,,,,,,31870,Colletotrichum graminicola,,CgM2,anthracnose (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Nathan,,,leaf,siderophore biosynthesis gene,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,reduced,no,ferricrocin; coprogen; coprogen B; methyl-coprogen B; H2O2; superoxide; rose bengal,ferricrocin: CHEBI:64492; H2O2: CHEBI:16240; superoxide: CHEBI:18421; rose bengal: CHEBI:52261,,,,,gene deletion: full; gene complementation,,,RP,24674132,PubMed,10.1111/mmi.12561,,holger.deising@landw.uni-halle.de,"Ferricrocin as well as spent medium of C. graminicola, containing coprogen, coprogen B, and methyl-coprogen B, fully restored conidiation in deletion mutants / sensitivity to ROS, either H2O2 or superoxide, generated by addition of rose bengal to the growth medium and incubation of plates under light, was severely increased in both mutants",E Albarouki 2014,2014,2 genes,Albarouki-2014-Biotrophy-specific downregulati,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5744,PHI:4217,UniProt,E3QPY3,GenBank,EFQ32921,,,M1.001,NPS6,,,,,,,31870,Colletotrichum graminicola,,CgM2,anthracnose (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Nathan,,,leaf,non-ribosomal peptide synthetase gene,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,reduced,no,ferricrocin; coprogen; coprogen B; methyl-coprogen B; H2O2; superoxide; rose bengal,ferricrocin: CHEBI:64492; H2O2: CHEBI:16240; superoxide: CHEBI:18421; rose bengal: CHEBI:52261,,,,,gene deletion: full; gene complementation,,,RP,24674132,PubMed,10.1111/mmi.12561,,holger.deising@landw.uni-halle.de,"Ferricrocin as well as spent medium of C. graminicola, containing coprogen, coprogen B, and methyl-coprogen B, fully restored conidiation in deletion mutants / sensitivity to ROS, either H2O2 or superoxide, gen-erated by addition of rose bengal to the growth medium and incubation of plates under light, was severely increased in both mutants.",E Albarouki 2014,2014,2 genes,Albarouki-2014-Biotrophy-specific downregulati,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5745,PHI:4218,UniProt,A1AEE9,GenBank,ABJ02039,,,APEC O1,smpB,,,,,,,562,Escherichia coli,,E058,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,blood; liver; spleen; lung; kidney,"trans-translation is a bacterial translational control system that directs the modification and degradation of proteins,",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24013628,PubMed,10.1128/JB.00628-13,,gsong@yzu.edu.cn,cardiac blood,X Mu 2013,2013,2 genes,Mu-2013-The transfer-messenger RNA-small prote,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5746,PHI:4219,UniProt,G4PXR6,Ecogene,945053,,,K-12,ssrA,,,,,,,562,Escherichia coli,,E058,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,blood; liver; spleen; lung; kidney,plays a key role in protein quality control,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24013628,PubMed,10.1128/JB.00628-13,,gsong@yzu.edu.cn,cardiac blood,X Mu 2013,2013,2 genes,Mu-2013-The transfer-messenger RNA-small prote,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5747,PHI:4220,UniProt,Q59N20,GenBank,EAK91855,,,SC5314,Mss11,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,transcriptional activator involved in biofilm formation,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24752399,PubMed,10.1007/s00438-014-0846-0,,wphsieh@stat.nthu.edu.tw,,P Tsai,2014,1 gene,Tsai-2014-The role of Mss11 in Candida albican,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5748,PHI:4221,UniProt,Q04JI6,GenBank,ABJ54564,,,D39,DacA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia,,,,Lethal pathogen phenotype,,,,diadenylate cyclase,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,24013631,PubMed,10.1128/JB.00769-13,,baig@mail.amc.edu,,Y Bai 2013,2013,3 genes,Bai-2013-Two DHH subfamily 1 proteins in Strep,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5749,PHI:4222,UniProt,Q04HX1,GenBank,ABJ55207,,,D39,Pde1,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,c-di-AMP phosphodiesterase activity,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,24013631,PubMed,10.1128/JB.00769-13,,baig@mail.amc.edu,,Y Bai 2013,2013,3 genes,Bai-2013-Two DHH subfamily 1 proteins in Strep,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5750,PHI:4223,UniProt,Q04K27,GenBank,ABJ54706,,,D39,Pde2,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,c-di-AMP phosphodiesterase activity,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,24013631,PubMed,10.1128/JB.00769-13,,baig@mail.amc.edu,,Y Bai 2013,2013,3 genes,Bai-2013-Two DHH subfamily 1 proteins in Strep,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5751,PHI:4222,UniProt,Q04HX1,GenBank,ABJ55207,,,D39,Pde1,,,,,,PHI:4223,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,c-di-AMP phosphodiesterase activity,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,24013631,PubMed,10.1128/JB.00769-13,,baig@mail.amc.edu,,Y Bai 2013,2013,3 genes,Bai-2013-Two DHH subfamily 1 proteins in Strep,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5752,PHI:4223,UniProt,Q04K27,GenBank,ABJ54706,,,D39,Pde2,,,,,,PHI:4222,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,c-di-AMP phosphodiesterase activity,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,24013631,PubMed,10.1128/JB.00769-13,,baig@mail.amc.edu,,Y Bai 2013,2013,3 genes,Bai-2013-Two DHH subfamily 1 proteins in Strep,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5753,PHI:4224,UniProt,Q2G2U1,GenBank,ABD20913,,,USA300_FPR3757,SaeS,,,,,,,1280,Staphylococcus aureus,867914,LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,neutrophil,histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,24782537,PubMed,10.1073/pnas.1322125111,,jovanka@montana.edu,,C E Flack 2014,2014,1 gene,Flack-2014-Differential regulation of staphylo,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5754,PHI:4225,UniProt,W7MPI5,GenBank,EWG49689,,,7600,SGE1,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize),monocots,4577,Zea mays (related: maize),subsp. mays cv. Silver Queen,,,leaf,regulates markedly different genes,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,24742071,PubMed,10.1094/MPMI-09-13-0281-R,,daren.brown@ars.usda.gov,,D W Brown 2014,2014,1 gene,Brown-2014-Fusarium verticillioides SGE1 is re,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5755,PHI:4226,,no data found,GenBank,XP_001551065,,,B05.10,BcAra1,,,,,,,40559,Botrytis cinerea,,IK2018,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia,,,leaf,"arabinan endo-1,5-alpha-L-arabinosidase",,,,reduced virulence,,,,,,,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,24725206,PubMed,10.1094/MPMI-02-14-0036-R,,ysa@life.ku.dk,,M Nafisi 2014,2014,1 gene,Nafisi-2014-The endo-arabinanase BcAra1 is a n,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5756,PHI:4226,,no data found,GenBank,XP_001551065,,,B05.10,BcAra1,,,,,,,40559,Botrytis cinerea,,IK2018,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,"arabinan endo-1,5-alpha-L-arabinosidase",,,,unaffected pathogenicity,,,,,same as wild type,,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,24725206,PubMed,10.1094/MPMI-02-14-0036-R,,ysa@life.ku.dk,,M Nafisi 2014,2014,1 gene,Nafisi-2014-The endo-arabinanase BcAra1 is a n,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5757,PHI:4226,,no data found,GenBank,XP_001551065,,,B05.10,BcAra1,,,,,,,40559,Botrytis cinerea,,IK2018,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,"arabinan endo-1,5-alpha-L-arabinosidase",,,,unaffected pathogenicity,,,,,same as wild type,,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,24725206,PubMed,10.1094/MPMI-02-14-0036-R,,ysa@life.ku.dk,,M Nafisi 2014,2014,1 gene,Nafisi-2014-The endo-arabinanase BcAra1 is a n,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5758,PHI:4227,,no data found,GenBank,XP_001551261,,,B05.10,BcRAS1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,small GTPases,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,reduced,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,24096906,PubMed,10.1128/EC.00160-13,,amirsh@ex.tau.ac.il,Colonies of the deltaras1 and deltarac strains are sensitive to osmotic and oxidative stress.,A M Dub 2013,2013,2 genes,Minz Dub-2013-Involvement of Botrytis cinerea,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5759,PHI:4228,,no data found,BROAD,B0510_7705,,,,BcRAC,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,small GTPases,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,reduced,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,24096906,PubMed,10.1128/EC.00160-13,,amirsh@ex.tau.ac.il,Colonies of the deltaras1 and deltarac strains are sensitive to osmotic and oxidative stress.,A M Dub 2013,2013,2 genes,Minz Dub-2013-Involvement of Botrytis cinerea,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5760,PHI:4229,UniProt,Q4X006,GenBank,EAL93809,,,Af293,abcA,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,ABC transporter-encoding genes,,,,unaffected pathogenicity,,,,,,,,,,no,voriconazole; itraconazole,voriconazole: CHEBI:10023; itraconazole: CHEBI:6076,,,,,gene deletion: full,,,RP,24123268,PubMed,10.1128/EC.00171-13,,scott-moye-rowley@uiowa.edu,,S Paul 2013,2013,2 genes,Paul-2013-Contributions of Aspergillus fumigat,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5761,PHI:4230,UniProt,E9RBG1,GenBank,EAL90765,,,Af293,abcB,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,ABC transporter-encoding genes,,,,reduced virulence,,,,,,,,,,no,voriconazole; itraconazole,voriconazole: CHEBI:10023; itraconazole: CHEBI:6076,,,,,gene deletion: full,,,RP,24123268,PubMed,10.1128/EC.00171-13,,scott-moye-rowley@uiowa.edu,,S Paul 2013,2013,2 genes,Paul-2013-Contributions of Aspergillus fumigat,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5762,PHI:4231,UniProt,G5EHM3,GenBank,EAQ71238,,,70-15,MoFLP1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,fasciclin-like protein encoding gene,,,,reduced virulence,,yes,,,few scattered lesions,reduced,,wild type,wild type,no,,,,,,,gene disruption,,,RP,19489109,PubMed,10.1631/jzus.B0920017,,fuchenglin@zju.edu.cn,,T LIU 2009,2009,1 gene,"Liu-2009-MoFLP1, encoding a novel fungal fasci",Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5763,PHI:4231,UniProt,G5EHM3,GenBank,EAQ71238,,,70-15,MoFLP1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,fasciclin-like protein encoding gene,,,,reduced virulence,,yes,,,few scattered lesions,reduced,,wild type,wild type,no,,,,,,,gene disruption,,,RP,19489109,PubMed,10.1631/jzus.B0920017,,fuchenglin@zju.edu.cn,,T LIU 2009,2009,1 gene,"Liu-2009-MoFLP1, encoding a novel fungal fasci",Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5764,PHI:4232,UniProt,Q5D6D3,GenBank,AAX09988,,,,nps6,,,,,,PHI:4233,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-N,,,leaf,encoding different nonribosomal peptide synthetases (NRPS) responsible for biosynthesis of siderophores,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2;KO2; bathophenanthroline disulfonate: CHEBI:78158,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,24762221,PubMed,10.1094/MPMI-11-13-0328-R,,bjc225@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,B J Condon 2014,2014,3 genes,Condon-2014-Reductive iron assimilation and in,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5765,PHI:4233,UniProt,N4X9G3,GenBank,ENI01852,,,ATCC 48331,ftr1,,,,,,PHI:4232,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-N,,,leaf,encoding the permease component,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2;KO2; bathophenanthroline disulfonate: CHEBI:78158,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,24762221,PubMed,10.1094/MPMI-11-13-0328-R,,bjc225@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,B J Condon 2014,2014,3 genes,Condon-2014-Reductive iron assimilation and in,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5766,PHI:4232,UniProt,Q5D6D3,GenBank,AAX09988,,,,nps6,,,,,,PHI:4233; PHI:4234,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-N,,,leaf,encoding different nonribosomal peptide synthetases (NRPS) responsible for biosynthesis of siderophores,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2;KO2; bathophenanthroline disulfonate: CHEBI:78158,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,24762221,PubMed,10.1094/MPMI-11-13-0328-R,,bjc225@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,B J Condon 2014,2014,3 genes,Condon-2014-Reductive iron assimilation and in,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5767,PHI:4233,UniProt,N4X9G3,GenBank,ENI01852,,,ATCC 48331,ftr1,,,,,,PHI:4232; PHI:4234,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-N,,,leaf,encoding the permease component,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2;KO2; bathophenanthroline disulfonate: CHEBI:78158,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,24762221,PubMed,10.1094/MPMI-11-13-0328-R,,bjc225@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,B J Condon 2014,2014,3 genes,Condon-2014-Reductive iron assimilation and in,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5768,PHI:4234,UniProt,Q5D6D7,GenBank,AAX09984,,,,nps2,,,,,,PHI:4232; PHI:4233,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A-N,,,leaf,encoding different nonribosomal peptide synthetases (NRPS) responsible for biosynthesis of siderophores,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2;KO2; bathophenanthroline disulfonate: CHEBI:78158,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,24762221,PubMed,10.1094/MPMI-11-13-0328-R,,bjc225@cornell.edu,Cochliobolus heterostrophus is pathogen anamorph name,B J Condon 2014,2014,3 genes,Condon-2014-Reductive iron assimilation and in,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5769,PHI:3532,UniProt,Q7W6Q2,GenBank,CAE38141,,,12822,Hfq,,,,,,,520,Bordetella pertussis,568706,18323,pertussis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,RNA chaperone,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,23980112,PubMed,10.1128/IAI.00345-13,,vecerek@biomed.cas.cz,,I Bibova 2013,2013,1 gene,Bibova-2013-The RNA chaperone Hfq is required,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5770,PHI:4235,UniProt,Q71ZE3,GenBank,AAT04321,,,F2365,SecDF,,,,,,,1639,Listeria monocytogenes,393133,10403S,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,membrane chaperone,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24056100,PubMed,10.1128/JB.00697-13,,anathe@post.tau.ac.il,,T Burg-Golani 2013,2013,1 gene,Burg-Golani-2013-Membrane chaperone SecDF play,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5771,PHI:4236,UniProt,I1RA07,GenBank,ESU05488,,,PH-1,MYT3,,,,,,,5518,Fusarium graminearum,,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,Myb-like transcription factor,,,,reduced virulence,yes,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,24722578,PubMed,10.1371/journal.pone.0094359,,lee2443@snu.ac.kr,,Y Kim 2014,2014,1 gene,"Kim-2014-MYT3, A Myb-Like Transcription Factor",Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5772,PHI:4237,UniProt,O74227,GenBank,AAC23576,,,C4,CGA1,,,,,,,5016,Bipolaris maydis,,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),subsp. mays cv. W64A,,,leaf,G protein alpha subunit,,,,unaffected pathogenicity,yes,yes,,,,wild type,reduced,,,no,NaCl; sorbitol,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924,,,,,gene deletion: full; gene complementation,,,RP,1007231,PubMed,10.1006/fgbi.1998.1094,,bgt1@cornell.edu,CGA1 is involved in sensing the osmotic condition of the external environment and sensitive to osmotic stress. Cochliobolus heterostrophus is pathogen anamorph name,B A Horwitz 1999,1999,1 gene,Horwitz-1999-A G protein alpha subunit from Co,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5773,PHI:4238,UniProt,P9WP65,GenBank,CCP43553,,,H37Rv,cnpB,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; lung,c-di-AMPphosphodiesterase activity and cleaves c-di-AMP exclusively to AMP,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,24806618,PubMed,10.1111/mmi.12641,,baig@mail.amc.edu,,J Yang 2014,2014,1 gene,Yang-2014-Deletion of the cyclic di-AMP phosph,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5774,PHI:4239,UniProt,E4QWW6,GenBank,ADO80307,,,R2866,opsX,,,,,,,727,Haemophilus influenzae,,375,respiratory infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,encodes a heptosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23980106,PubMed,10.1128/IAI.00492-13,,juncal.garmendia@unavarra.es,,P Morey 2013,2013,3 genes,Morey-2013-Relative contributions of lipooligo,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5775,PHI:4240,UniProt,E7AEJ2,GenBank,CBY86208,,,F3047,lgtF,,,,,,,727,Haemophilus influenzae,,375,respiratory infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,encodes aglycosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23980106,PubMed,10.1128/IAI.00492-13,,juncal.garmendia@unavarra.es,,P Morey 2013,2013,3 genes,Morey-2013-Relative contributions of lipooligo,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5776,PHI:4241,UniProt,Q0ZB06,GenBank,ABG48528,,,375,lpsA,,,,,,,727,Haemophilus influenzae,,375,respiratory infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,encodes aglycosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,23980106,PubMed,10.1128/IAI.00492-13,,juncal.garmendia@unavarra.es,,P Morey 2013,2013,3 genes,Morey-2013-Relative contributions of lipooligo,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5777,PHI:4242,UniProt,Q6WER3,GenBank,AAQ23181,,,,Fgl1,,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,eudicots,3847,Glycine max (related: soybean),cv. Demetra,,,seed; seedling,lipid metabolic process,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24779355,PubMed,10.1094/PHYTO-12-13-0355-R,,francesco.favaron@unipd.it,,L Sella 2014,2014,5 genes,Sella-2014-Fusarium graminearum possesses viru,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5778,PHI:4243,UniProt,Q00909,GenBank,AAB72033,,,w-8,TRI5,,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,eudicots,3847,Glycine max (related: soybean),cv. Demetra,,,seed; seedling,first enzyme in the DON and NIV biosynthetic pathway,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24779355,PubMed,10.1094/PHYTO-12-13-0355-R,,francesco.favaron@unipd.it,,L Sella 2014,2014,5 genes,Sella-2014-Fusarium graminearum possesses viru,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5779,PHI:4244,UniProt,I1S0C0,GenBank,ESU16819,,,PH-1,FgOS-2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3847,Glycine max (related: soybean),cv. Demetra,,,seed; seedling,stress activated protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24779355,PubMed,10.1094/PHYTO-12-13-0355-R,,francesco.favaron@unipd.it,,L Sella 2014,2014,5 genes,Sella-2014-Fusarium graminearum possesses viru,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5780,PHI:4245,UniProt,I1RQN9,GenBank,AAL73403,,,,MAP1 (related: GPMK1),,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,eudicots,3847,Glycine max (related: soybean),cv. Demetra,,,seed; seedling,regulates the secretion of cell wall degrading enzymes,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24779355,PubMed,10.1094/PHYTO-12-13-0355-R,,francesco.favaron@unipd.it,,L Sella 2014,2014,5 genes,Sella-2014-Fusarium graminearum possesses viru,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5781,PHI:4246,UniProt,I1S3C6,GenBank,ESU18318,,,PH-1,xyl03624,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3847,Glycine max (related: soybean),cv. Demetra,,,seed; seedling,degradation of xylan components of plant cell wall,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,24779355,PubMed,10.1094/PHYTO-12-13-0355-R,,francesco.favaron@unipd.it,,L Sella 2014,2014,5 genes,Sella-2014-Fusarium graminearum possesses viru,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5782,PHI:4247,UniProt,Q8NZ78,GenBank,AAL98547,,,MGAS8232,mga,,,,,,,1314,Streptococcus pyogenes,198466,MGAS315,pharyngitis; toxic shock syndrome; sepsis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,global positive gene regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,23980109,PubMed,10.1128/IAI.00405-13,,JMMusser@HoustonMethodist.org,,A R Flores 2013,2013,1 gene,Flores-2013-Natural variation in the promoter,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5783,PHI:4248,UniProt,B0XPI3,GenBank,EDP55956,,,A1163,PerA,,,,,,,746128,Aspergillus fumigatus,,CBS 144.89,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,GPI lipid remodelling protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,aberrant,no,calcofluor white (CFW); Congo red (CR); caspofungin; voriconazole,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023,,,,,gene deletion: full; gene complementation,,,RP,24779420,PubMed,10.1111/mmi.12626,,Robert.A.Cramer.Jr@dartmouth.edu,Mutants show striking defects in cell wall integrity and increased susceptibility to triazole antifungal drugs.,D Chung 2014,2014,1 gene,Chung-2014-Endoplasmic reticulum localized Per,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5784,PHI:4249,UniProt,C5ACN1,GenBank,ACR28061,,,BGR1,aroA,,,,,,,337,Burkholderia glumae,,411gr-6,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Bengal,,,panicle,3-phosphoshikimate 1-carboxyvinyltransferase,,,shikimate pathway,reduced virulence,,,,,,,,reduced; aberrant,,no,phenylalanine; tryptophan; tyrosine,phenylalanine: CHEBI:28044; tryptophan: CHEBI:27897; tyrosine: CHEBI:18186,,,,,gene mutation,,,RP,24754446,PubMed,10.1111/mpp.12147,,jham@agcenter.lsu.edu,"The growth defect of the aroA and aroB mutants was restored in M9 medium supplemented with the three aromatic amino acids (phenylalanine, tryptophan and tyrosine).",H S KARKI 2014,2014,2 genes,Karki-2014-The roles of the shikimate pathway,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5785,PHI:4250,UniProt,C5A9K4,GenBank,ACR27505,,,BGR1,aroB,,,,,,,337,Burkholderia glumae,,411gr-6,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Bengal,,,panicle,3-dehydroquinate synthase,,,shikimate pathway,reduced virulence,,,,,,,,reduced; aberrant,,no,phenylalanine; tryptophan; tyrosine,phenylalanine: CHEBI:28044; tryptophan: CHEBI:27897; tyrosine: CHEBI:18186,,,,,gene mutation,,,RP,24754446,PubMed,10.1111/mpp.12147,,jham@agcenter.lsu.edu,"The growth defect of the aroA and aroB mutants was restored in M9 medium supplemented with the three aromatic amino acids (phenylalanine, tryptophan and tyrosine).",H S KARKI 2014,2014,2 genes,Karki-2014-The roles of the shikimate pathway,Batch038,2014-06-01,MC,,,,,,,,,,,,,
,,Record 5786,PHI:4561,UniProt,Q59PZ5,GenBank,EAK92556,,,SC5314,Gcn5,,ura3::imm434::URA3/ura3::imm434iro1::IRO1/iro1::imm434his1::hisG/his1::hisGleu2/leu2 arg4/arg4 gcn5::PLP/gcn5::PHP,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,loss of pathogenicity,,,,,,,,aberrant,,no,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; H2O2: CHEBI:16240; Congo red: CHEBI:34653,"hydroxyurea,   methyl   methanesulfonate,   camptothecin,   H2O2",,,,,gene mutation; gene complementation,,,RP,25656079,PubMed,10.1016/j.fgb.2015.01.011,Fungal Genet Biol. 2015 Feb 3. pii: S1087-1845(15)00014-6,jychen@sibcb.ac.cn,The gcn5mutant strain did not show growth defects in response to genotoxic and oxidative stresses but is is required for cell wall stress response.,P Chang 2015,2015,1 gene,Chang-2015-Function and subcellular localizati,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5787,PHI:4562,UniProt,P0CE18,GenBank,CAA29894,,,L1/440/LN,CDS5 (pgp3),,L2P-25667R transformed with pGFP::SW2 with a functional deletion in plasmid CDS5 which encodes the putative virulence effector pgp3,,,,,813,Chlamydia trachomatis,,25667R,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,reproductive system,virulence effector,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24866804,PubMed,10.1128/IAI.01795-14,Infect Immun. 2014 Aug;82(8):3341-9,kramse@midwestern.edu,,K H Ramsey 2014,2014,1 gene,Ramsey-2014-Plasmid coding sequence-five influ,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5788,PHI:4563,UniProt,Q0WEH7,GenBank,CAL20972,,,CO92,TyrR,,,,,,,632,Yersinia pestis,,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,regulator of aromatic amino acid metabolism,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25729381,PubMed,10.3389/fmicb.2015.00110,Front Microbiol. 2015 Feb 12;6:110,ruifuyang@gmail.com,,Z Deng 2015,2015,1 gene,"Deng-2015-TyrR, the regulator of aromatic amin",BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5789,PHI:4564,UniProt,I3U3N8,GenBank,AFK59626,,,DO,CcpA,,TX82deltaccpA;ccpAdeletion mutant,,,,,1352,Enterococcus faecium,749520,TX82,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,global transcriptional regulator of carbon catabolite repression,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,24914215,PubMed,10.1128/IAI.01911-14,Infect Immun. 2014 Sep;82(9):3580-7,bem.asst@uth.tmc.edu,,S R Somarajan 2014,2014,2 genes,Somarajan-2014-CcpA is Important for Growth an,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5790,PHI:4565,UniProt,Q3XXN7,GenBank,AFK59905,,,DO,Acm,,TX82deltaacm; nonpolar markerlessacmdeletion mutant,,,,,1352,Enterococcus faecium,749520,TX82,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,collagen adhesin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24914215,PubMed,10.1128/IAI.01911-14,Infect Immun. 2014 Sep;82(9):3580-7,bem.asst@uth.tmc.edu,,S R Somarajan 2014,2014,2 genes,Somarajan-2014-CcpA is Important for Growth an,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5791,PHI:4566,UniProt,D8HH62,GenBank,ADI99195,,,ED133,clfA,,,,,,,1280,Staphylococcus aureus,,SF8300,community-acquired infection; nosocomial infection,rodents,10114,Rattus (related: rat),Cotton,,,heart,fibrinogen-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25691592,PubMed,10.1128/mBio.02272-14,MBio. 2015 Feb 17;6(1):e02272-14,sellmanb@medimmune.com,,A Jenkins 2015,2015,6 genes,Jenkins-2015-Differential expression and roles,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5792,PHI:4567,UniProt,D8HGI0,GenBank,ADI97114,,,ED133,sdrC,,,,,,,1280,Staphylococcus aureus,,SF8300,community-acquired infection; nosocomial infection,rodents,10114,Rattus (related: rat),Cotton,,,heart,adhesins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25691592,PubMed,10.1128/mBio.02272-14,MBio. 2015 Feb 17;6(1):e02272-14,sellmanb@medimmune.com,,A Jenkins 2015,2015,6 genes,Jenkins-2015-Differential expression and roles,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5793,PHI:4568,UniProt,Q2FZF0,GenBank,AAL33769,,,,isdB,,,,,,,1280,Staphylococcus aureus,,SF8300,community-acquired infection; nosocomial infection,rodents,10114,Rattus (related: rat),Cotton,,,heart,iron-regulated cell wall-anchored protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25691592,PubMed,10.1128/mBio.02272-14,MBio. 2015 Feb 17;6(1):e02272-14,sellmanb@medimmune.com,,A Jenkins 2015,2015,6 genes,Jenkins-2015-Differential expression and roles,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5794,PHI:4569,UniProt,A6QG63,GenBank,BAF67345,,,Newman,hla,,,,,,,1280,Staphylococcus aureus,,SF8300,community-acquired infection; nosocomial infection,rodents,10114,Rattus (related: rat),Cotton,,,heart,alpha-hemolysin precursor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25691592,PubMed,10.1128/mBio.02272-14,MBio. 2015 Feb 17;6(1):e02272-14,sellmanb@medimmune.com,,A Jenkins 2015,2015,6 genes,Jenkins-2015-Differential expression and roles,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5795,PHI:4570,UniProt,P02976,GenBank,ABD29253,,,NCTC 8325,spa,,,,,,,1280,Staphylococcus aureus,,SF8300,community-acquired infection; nosocomial infection,rodents,10114,Rattus (related: rat),Cotton,,,heart,immunoglobulin G-binding protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25691592,PubMed,10.1128/mBio.02272-14,MBio. 2015 Feb 17;6(1):e02272-14,sellmanb@medimmune.com,,A Jenkins 2015,2015,6 genes,Jenkins-2015-Differential expression and roles,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5796,PHI:4571,UniProt,U5T3C0,GenBank,AGY90848,,,Z172,clfB,,,,,,PHI:4567,1280,Staphylococcus aureus,,SF8300,community-acquired infection; nosocomial infection,rodents,10114,Rattus (related: rat),Cotton,,,heart,fibrinogen-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25691592,PubMed,10.1128/mBio.02272-14,MBio. 2015 Feb 17;6(1):e02272-14,sellmanb@medimmune.com,,A Jenkins 2015,2015,6 genes,Jenkins-2015-Differential expression and roles,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5797,PHI:4567,UniProt,D8HGI0,GenBank,ADI97114,,,ED133,sdrC,,,,,,PHI:4571,1280,Staphylococcus aureus,,SF8300,community-acquired infection; nosocomial infection,rodents,10114,Rattus (related: rat),Cotton,,,heart,adhesins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25691592,PubMed,10.1128/mBio.02272-14,MBio. 2015 Feb 17;6(1):e02272-14,sellmanb@medimmune.com,,A Jenkins 2015,2015,6 genes,Jenkins-2015-Differential expression and roles,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5798,PHI:4572,UniProt,Q7VM28,GenBank,AAP96035,,,35000HP,relA,,35000HPdeltarelA,,,,,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24914217,PubMed,10.1128/IAI.01994-14,Infect Immun. 2014 Aug;82(8):3492-502,sspinola@iu.edu,,C Holley 2014,2014,2 genes,Holley-2014-A (p)ppGpp null mutant of Haemophi,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5799,PHI:4573,UniProt,Q7U332,GenBank,AAP96646,,,35000HP,spoT,,35000HPdeltarelAdeltaspoT,,,,PHI:4572,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,,"guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24914217,PubMed,10.1128/IAI.01994-14,Infect Immun. 2014 Aug;82(8):3492-502,sspinola@iu.edu,,C Holley 2014,2014,2 genes,Holley-2014-A (p)ppGpp null mutant of Haemophi,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5800,PHI:4572,UniProt,Q7VM28,GenBank,AAP96035,,,35000HP,relA,,35000HPdeltarelAdeltaspoT,,,,PHI:4573,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,24914217,PubMed,10.1128/IAI.01994-14,Infect Immun. 2014 Aug;82(8):3492-502,sspinola@iu.edu,,C Holley 2014,2014,2 genes,Holley-2014-A (p)ppGpp null mutant of Haemophi,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5801,PHI:4574,UniProt,Q059G5,GenBank,AFR93292,,,H99,NTH1,,MATalpha nth1::NATR,,,,,5207,Cryptococcus neoformans,214684,JEC21,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,trehalose homeostasis,,,,increased virulence (hypervirulence),,,,,,reduced,,,reduced,no,,,,,,,gene deletion: full,,,RP,25001408,PubMed,10.1128/EC.00152-14,Eukaryot Cell. 2014 Sep;13(9):1158-68,cmhull@wisc.edu,,M R Botts 2014,2014,2 genes,Botts-2014-Developmental cell fate and virulen,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5802,PHI:4575,UniProt,Q5KEF4,GenBank,AAW44482,,,JEC21,NTH2,,MATalpha nth2::NEOR,,,,,5207,Cryptococcus neoformans,214684,JEC21,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,trehalose homeostasis,,,,increased virulence (hypervirulence),,,,,,reduced,,,reduced,no,,,,,,,gene deletion: full,,,RP,25001408,PubMed,10.1128/EC.00152-14,Eukaryot Cell. 2014 Sep;13(9):1158-68,cmhull@wisc.edu,,M R Botts 2014,2014,2 genes,Botts-2014-Developmental cell fate and virulen,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5803,PHI:4574,UniProt,Q059G5,GenBank,AFR93292,,,H99,NTH1,,MATalpha nth1::NATR,,,,PHI:4575,5207,Cryptococcus neoformans,214684,JEC21,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,trehalose homeostasis,,,,increased virulence (hypervirulence),,,,,,reduced,,,reduced,no,,,,,,,gene deletion: full,,,RP,25001408,PubMed,10.1128/EC.00152-14,Eukaryot Cell. 2014 Sep;13(9):1158-68,cmhull@wisc.edu,,M R Botts 2014,2014,2 genes,Botts-2014-Developmental cell fate and virulen,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5804,PHI:4575,UniProt,Q5KEF4,GenBank,AAW44482,,,JEC21,NTH2,,MATalpha nth2::NEOR,,,,PHI:4574,5207,Cryptococcus neoformans,214684,JEC21,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,trehalose homeostasis,,,,increased virulence (hypervirulence),,,,,,reduced,,,reduced,no,,,,,,,gene deletion: full,,,RP,25001408,PubMed,10.1128/EC.00152-14,Eukaryot Cell. 2014 Sep;13(9):1158-68,cmhull@wisc.edu,,M R Botts 2014,2014,2 genes,Botts-2014-Developmental cell fate and virulen,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5805,PHI:4576,UniProt,P0DKY7,GenBank,AAA74502,,,71,RsmA,,,,,,,554,Pectobacterium carotovorum,555,subsp. carotovorum strain Ecc71,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,carbon storage regulator homolog,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,8810071,PubMed,10.1094/MPMI-9-0565,Mol Plant Microbe Interact. 1996 Sep;9(7):565-73.,achatterjee@psu.missouri.edu,,Y Cui 1996,1996,1 gene,Cui-1996-The RsmA- mutants of Erwinia carotovo,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5806,PHI:4577,UniProt,Q836D3,GenBank,AAO80981,,,V583,AI-2,,,,,,,1351,Enterococcus faecalis,1261557,Symbioflor 1,probiotic gut bacteria,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gut,quorum sensing,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence,,,RP,25706310,PubMed,10.1371/journal.ppat.1004653,PLoS Pathog. 2015 Feb 23;11(2):e1004653,johannes.huebner@med.uni-muenchen.de,"Symbioflor 1 was exposed to phage-containing culture supernatants from E. Faecalis V583deltaABC in which phages were released by AI-2; this leads to uptake of virulence genes and makes an otherwise probiotic strain, virulent. pretreatment with recombinant rsil prior to infection with the pathogen.",F S Rossmann 2015,2015,1 gene,Rossmann-2015-Phage-mediated Dispersal of Biof,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5807,PHI:4579,UniProt,P0A082,GenBank,BAB42453,,,N315,msrA1,,SH1000:msrA1 SH1000 with mutation in themsrA1gene (KanR),,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5808,PHI:4580,UniProt,P0A086,GenBank,AF349112_1,,,,msrA2,,SH1000:msrA2 SH1000 with mutation in themsrA2gene (TetR),,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5809,PHI:4581,UniProt,K0M3M4,GenBank,CCJ12904,,,ST228,msrA3,,SH1000:msrA3 SH1000 with mutation in themsrA3gene (ErmR),,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5810,PHI:4582,UniProt,P0A088,GenBank,AF349112_2,,,,msrB,,SH1000:msrB SH1000 with mutation in themsrBgene (KanR),,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5811,PHI:4579,UniProt,P0A082,GenBank,BAB42453,,,N315,msrA1,,"SH1000:msrAB SH1000 with mutation in themsrA1, msrA2, msrA3, and msrBgenes (KanR, TetR, ErmR)",,,,PHI:4580; PHI:4581; PHI:4582,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5812,PHI:4580,UniProt,P0A086,GenBank,AF349112_1,,,,msrA2,,"SH1000:msrAB SH1000 with mutation in themsrA1, msrA2, msrA3, and msrBgenes (KanR, TetR, ErmR)",,,,PHI:4579; PHI:4581; PHI:4582,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5813,PHI:4581,UniProt,K0M3M4,GenBank,CCJ12904,,,ST228,msrA3,,"SH1000:msrAB SH1000 with mutation in themsrA1, msrA2, msrA3, and msrBgenes (KanR, TetR, ErmR)",,,,PHI:4579; PHI:4580; PHI:4582,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5814,PHI:4582,UniProt,P0A088,GenBank,AF349112_2,,,,msrB,,"SH1000:msrAB SH1000 with mutation in themsrA1, msrA2, msrA3, and msrBgenes (KanR, TetR, ErmR)",,,,PHI:4579; PHI:4580; PHI:4581,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5815,PHI:4579,UniProt,P0A082,GenBank,BAB42453,,,N315,msrA1,,"SH1000:msrA SH1000 with mutation in themsrA1, msrA2andmsrA3genes (KanR,TetR, ErmR)",,,,PHI:4580; PHI:4581,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5816,PHI:4580,UniProt,P0A086,GenBank,AF349112_1,,,,msrA2,,"SH1000:msrA SH1000 with mutation in themsrA1, msrA2andmsrA3genes (KanR,TetR, ErmR)",,,,PHI:4579; PHI:4581,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5817,PHI:4581,UniProt,K0M3M4,GenBank,CCJ12904,,,ST228,msrA3,,"SH1000:msrA SH1000 with mutation in themsrA1, msrA2andmsrA3genes (KanR,TetR, ErmR)",,,,PHI:4579; PHI:4580,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss white Hla (ICR)CVF,,,liver; spleen,methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25680075,PubMed,10.1371/journal.pone.0117594,PLoS One. 2015 Feb 13;10(2):e0117594,vsingh@atsu.edu,Mutants sensitive to oxidative stress,V K Singh 2015,2015,4 genes,Singh-2015-Significance of Four Methionine Sul,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5818,PHI:4583,UniProt,C9Y236,GenBank,CBA34185,,,z3032,FkpA,,,,,,,413502,Cronobacter turicensis,,LMG 23827,meningitis; bacteremia,primates,9606,Homo sapiens (related: human),,,,THP-1 cell,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25724920,PubMed,10.1016/j.resmic.2015.02.005,Res Microbiol. 2015 Feb 25. pii: S0923-2508(15)00034-0,athmanya.eshwar@uzh.ch,The influence of the gene on macrophage survival and replication varies among strains and/or species due to the presence of amino acid variations.,A K Eshwar 2015,2015,2 genes,Eshwar-2015-Influence of FkpA variants on surv,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5819,PHI:4584,UniProt,K8DPN9,GenBank,CCK16247,,,NCTC 9529,FkpA,,,,,,,535744,Cronobacter universalis,,LMG 26249,meningitis; bacteremia,primates,9606,Homo sapiens (related: human),,,,THP-1 cell,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25724920,PubMed,10.1016/j.resmic.2015.02.005,Res Microbiol. 2015 Feb 25. pii: S0923-2508(15)00034-0,athmanya.eshwar@uzh.ch,The influence of the gene on macrophage survival and replication varies among strains and/or species due to the presence of amino acid variations.,A K Eshwar 2015,2015,2 genes,Eshwar-2015-Influence of FkpA variants on surv,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5820,PHI:4585,UniProt,Q4P4E0,GenBank,EAK85883,,,521,Hxt1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),,,,leaf,hexose transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25678342,PubMed,10.1111/nph.13314,New Phytol. 2015 Feb 10,joerg.kaemper@kit.edu,Growth reduced on hexose source,D Schuler 2015,2015,2 genes,"Schuler-2015-Hxt1, a monosaccharide transporte",BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5821,PHI:4586,UniProt,Q4PBY9,GenBank,EAK83412,,,521,Srt1,,,,,,PHI:4585,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),,,,leaf,hexose transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25678342,PubMed,10.1111/nph.13314,New Phytol. 2015 Feb 10,joerg.kaemper@kit.edu,Growth reduced on hexose source,D Schuler 2015,2015,2 genes,"Schuler-2015-Hxt1, a monosaccharide transporte",BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5822,PHI:4585,UniProt,Q4P4E0,GenBank,EAK85883,,,521,Hxt1,,,,,,PHI:4586,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),,,,leaf,hexose transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25678342,PubMed,10.1111/nph.13314,New Phytol. 2015 Feb 10,joerg.kaemper@kit.edu,Growth reduced on hexose source,D Schuler 2015,2015,2 genes,"Schuler-2015-Hxt1, a monosaccharide transporte",BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5823,PHI:4587,UniProt,I1RT36,GenBank,ESU13572,,,PH-1,Fgk3,,,,FgMSN2,UniProt: I1RRX1,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,glycogen synthase kinase,,,,loss of pathogenicity,yes,,,,,reduced,reduced,reduced; aberrant,reduced,no,H2O2; NaCl; Congo red; SDS,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,RP,25703795,PubMed,10.1038/srep08504,Sci Rep. 2015 Feb 23;5:8504,wangchenfang@nwsuaf.edu.cn,,J Qin 2015,2015,1 gene,Qin-2015-Fgk3 glycogen synthase kinase is impo,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5824,PHI:4588,UniProt,G7TIV7,GenBank,AEQ94400,,,BLS256,AvrBs2,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25688911,PubMed,10.1094/MPMI-10-14-0314-R,Mol Plant Microbe Interact. 2015 Feb 17,wxs@cau.edu.cn,,S Li 2015,2015,7 genes,Li-2015-The Type III Effector AvrBs2 in Xantho,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5825,PHI:4589,UniProt,G7TAC5,GenBank,AEQ98514,,,BLS256,XopAA,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25688911,PubMed,10.1094/MPMI-10-14-0314-R,Mol Plant Microbe Interact. 2015 Feb 17,wxs@cau.edu.cn,,S Li 2015,2015,7 genes,Li-2015-The Type III Effector AvrBs2 in Xantho,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5826,PHI:4588,UniProt,G7TIV7,GenBank,AEQ94400,,,BLS256,AvrBs2,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Jinhe 2,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25688911,PubMed,10.1094/MPMI-10-14-0314-R,Mol Plant Microbe Interact. 2015 Feb 17,wxs@cau.edu.cn,,S Li 2015,2015,7 genes,Li-2015-The Type III Effector AvrBs2 in Xantho,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5827,PHI:4589,UniProt,G7TAC5,GenBank,AEQ98514,,,BLS256,XopAA,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Jinhe 2,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25688911,PubMed,10.1094/MPMI-10-14-0314-R,Mol Plant Microbe Interact. 2015 Feb 17,wxs@cau.edu.cn,,S Li 2015,2015,7 genes,Li-2015-The Type III Effector AvrBs2 in Xantho,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5828,PHI:4590,UniProt,G7TLG0,GenBank,AEQ94587,,,BLS256,XopN,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,gene mutation; gene complementation,,,RP,25688911,PubMed,10.1094/MPMI-10-14-0314-R,Mol Plant Microbe Interact. 2015 Feb 17,wxs@cau.edu.cn,,S Li 2015,2015,7 genes,Li-2015-The Type III Effector AvrBs2 in Xantho,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5829,PHI:4591,UniProt,G7TBE7,GenBank,AEQ94827,,,BLS256,XopX,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,gene mutation; gene complementation,,,RP,25688911,PubMed,10.1094/MPMI-10-14-0314-R,Mol Plant Microbe Interact. 2015 Feb 17,wxs@cau.edu.cn,,S Li 2015,2015,7 genes,Li-2015-The Type III Effector AvrBs2 in Xantho,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5830,PHI:4592,UniProt,G7TAA8,GenBank,AEQ98497,,,BLS256,XopA,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,gene mutation; gene complementation,,,RP,25688911,PubMed,10.1094/MPMI-10-14-0314-R,Mol Plant Microbe Interact. 2015 Feb 17,wxs@cau.edu.cn,,S Li 2015,2015,7 genes,Li-2015-The Type III Effector AvrBs2 in Xantho,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5831,PHI:4593,UniProt,G7TDQ2,GenBank,AEQ97580,,,BLS256,XopY,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,gene mutation; gene complementation,,,RP,25688911,PubMed,10.1094/MPMI-10-14-0314-R,Mol Plant Microbe Interact. 2015 Feb 17,wxs@cau.edu.cn,,S Li 2015,2015,7 genes,Li-2015-The Type III Effector AvrBs2 in Xantho,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5832,PHI:4594,UniProt,G7TAD0,GenBank,AEQ98519,,,BLS256,XopF1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,gene mutation; gene complementation,,,RP,25688911,PubMed,10.1094/MPMI-10-14-0314-R,Mol Plant Microbe Interact. 2015 Feb 17,wxs@cau.edu.cn,,S Li 2015,2015,7 genes,Li-2015-The Type III Effector AvrBs2 in Xantho,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5833,PHI:4588,UniProt,G7TIV7,GenBank,AEQ94400,,,BLS256,AvrBs2,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,gene mutation; gene complementation,,,RP,25688911,PubMed,10.1094/MPMI-10-14-0314-R,Mol Plant Microbe Interact. 2015 Feb 17,wxs@cau.edu.cn,,S Li 2015,2015,7 genes,Li-2015-The Type III Effector AvrBs2 in Xantho,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5834,PHI:4595,UniProt,Q885Y7,GenBank,AAO55214,,,DC3000,relA,,"Kmr, relA-::Kan, DC3000 derivative",,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25675257,PubMed,10.1094/MPMI-11-14-0378-R,Mol Plant Microbe Interact. 2015 Feb 12,zhao888@illinois.edu,(p)ppGpp is required fro oxidative response,T Chatnaparat 2015,2015,3 genes,Chatnaparat-2015-The stringent response mediat,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5835,PHI:4595,UniProt,Q885Y7,GenBank,AAO55214,,,DC3000,relA,,"Kmr, relA andspoT-::Kan, DC3000 derivative",,,,PHI:4596,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25675257,PubMed,10.1094/MPMI-11-14-0378-R,Mol Plant Microbe Interact. 2015 Feb 12,zhao888@illinois.edu,(p)ppGpp is required fro oxidative response,T Chatnaparat 2015,2015,3 genes,Chatnaparat-2015-The stringent response mediat,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5836,PHI:4596,UniProt,Q88BE4,GenBank,AAO53627,,,DC3000,spoT,,"Kmr, relA andspoT-::Kan, DC3000 derivative",,,,PHI:4595,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,"guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase",,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25675257,PubMed,10.1094/MPMI-11-14-0378-R,Mol Plant Microbe Interact. 2015 Feb 12,zhao888@illinois.edu,(p)ppGpp is required fro oxidative response,T Chatnaparat 2015,2015,3 genes,Chatnaparat-2015-The stringent response mediat,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5837,PHI:4595,UniProt,Q885Y7,GenBank,AAO55214,,,DC3000,relA,,"Kmr, relA, spoT andfpRel-::Kan, DC3000 derivative",,,,PHI:4597; PHI:4596,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25675257,PubMed,10.1094/MPMI-11-14-0378-R,Mol Plant Microbe Interact. 2015 Feb 12,zhao888@illinois.edu,(p)ppGpp is required fro oxidative response,T Chatnaparat 2015,2015,3 genes,Chatnaparat-2015-The stringent response mediat,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5838,PHI:4597,UniProt,Q889A5,GenBank,AAO54391,,,DC3000,fpRel,,"Kmr, relA, spoT andfpRel-::Kan, DC3000 derivative",,,,PHI:4595; PHI:4596,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,alarmone synthetase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25675257,PubMed,10.1094/MPMI-11-14-0378-R,Mol Plant Microbe Interact. 2015 Feb 12,zhao888@illinois.edu,(p)ppGpp is required fro oxidative response,T Chatnaparat 2015,2015,3 genes,Chatnaparat-2015-The stringent response mediat,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5839,PHI:4596,UniProt,Q88BE4,GenBank,AAO53627,,,DC3000,spoT,,"Kmr, relA, spoT andfpRel-::Kan, DC3000 derivative",,,,PHI:4597; PHI:4595,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,"guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase",,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,25675257,PubMed,10.1094/MPMI-11-14-0378-R,Mol Plant Microbe Interact. 2015 Feb 12,zhao888@illinois.edu,(p)ppGpp is required fro oxidative response,T Chatnaparat 2015,2015,3 genes,Chatnaparat-2015-The stringent response mediat,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5840,PHI:4596,UniProt,Q88BE4,GenBank,AAO53627,,,DC3000,spoT,,"Kmr, relA, spoT andfpRel-::Kan, DC3000 derivative",,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),,,,Lethal pathogen phenotype,,,,"guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase",,,,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,25675257,PubMed,10.1094/MPMI-11-14-0378-R,Mol Plant Microbe Interact. 2015 Feb 12,zhao888@illinois.edu,(p)ppGpp is required fro oxidative response,T Chatnaparat 2015,2015,3 genes,Chatnaparat-2015-The stringent response mediat,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5841,PHI:4598,UniProt,G2XIG0,GenBank,EGY19608,,,VdLs.17,VdPR3,,,,,,,27337,Verticillium dahliae,,Vd080,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Jimian 11,,,leaf,pathogenicity-related gene,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25652159,PubMed,10.1007/s00294-015-0476-z,Curr Genet. 2015 Feb 5,heqinanyang@163.com,,Y Zhang 2015,2015,1 gene,Zhang-2015-Isolation and functional analysis o,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5842,PHI:4599,UniProt,A9JX05,GenBank,DAA06122,,,MW2,psmalpha,,psmalpha pTxdelta -psmalpha,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,skin; lung,alpha-toxin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24866799,PubMed,10.1128/IAI.00089-14,Infect Immun. 2014 Aug;82(8):3350-8,jbubeckw@peds.bsd.uchicago.edu,,B J Berube 2014,2014,1 gene,Berube-2014-The psmalpha locus regulates produ,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5843,PHI:4600,UniProt,A0A088MWZ0,GenBank,AIN46816,,,HS-F6,sreA,,,,,,,36651,Penicillium digitatum,,HS-F6,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruit,HLH transcriptional factor,,,,reduced virulence,,,,,,,,wild type,,no,prochloraz,prochloraz: CHEBI:8434,,,,,gene disruption; gene complementation,,,RP,25699519,PubMed,10.1371/journal.pone.0117115,PLoS One. 2015 Feb 20;10(2):e0117115,ldl@mail.ccnu.edu.cn,Mutants led to increased susceptibility to prochloraz,J Liu 2015,2015,1 gene,Liu-2015-A Novel Sterol Regulatory Element-Bin,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5844,PHI:4601,UniProt,K3VCL0,GenBank,EKJ71677,,,CS3096,FDB2,,,,,,,101028,Fusarium pseudograminearum,1028729,CS3096,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kennedy,,,spike,N-malonyltransferase encoding gene,,,,reduced virulence,,,,,,,,wild type,,no,benzoxazolin-2-one (BOA); 6-methoxy-benzoxazolin-2-one (MBOA),benzoxazolin-2-one (BOA): CAS:59-49-4; 6-methoxy-benzoxazolin-2-one (MBOA): CAS:532-91-2,,,,,gene deletion: full; gene complementation,,,RP,25727347,PubMed,10.1111/mpp.12250,Mol Plant Pathol. 2015 Feb 24,Andrew.Kettle@csiro.au,deltafdb2 strains showed significantly reduced growth on media amended with BOA or MBOA,A J Kettle 2015,2015,2 genes,Kettle-2015-Degradation of the benzoxazolinone,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5845,PHI:4602,UniProt,I1RMW9,EMBL,FGRAMPH1_01T17619,,,CS3005,FDB2,,,,,,,5518,Fusarium graminearum,1450154,CS3005,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kennedy,,,spike,N-malonyltransferase encoding gene,,,,reduced virulence,,,,,,,,wild type,,no,benzoxazolin-2-one (BOA); 6-methoxy-benzoxazolin-2-one (MBOA),benzoxazolin-2-one (BOA): CAS:59-49-4; 6-methoxy-benzoxazolin-2-one (MBOA): CAS:532-91-2,,,,,gene deletion: full; gene complementation,,,RP,25727347,PubMed,10.1111/mpp.12250,Mol Plant Pathol. 2015 Feb 24,Andrew.Kettle@csiro.au,"The F. graminearum FDB2 mutant did not show an additional reduction in growth of MBOA, consistent with the greater MBOA sensitivity of F. graminearum.",A J Kettle 2015,2015,2 genes,Kettle-2015-Degradation of the benzoxazolinone,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5846,PHI:4603,UniProt,Q4WQI8,GenBank,EAL89496,,,Af293,KexB,,,,,,,746128,Aspergillus fumigatus,,ku80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),immunocompromised mice,,,lung,kexin-like endoprotease,,,MpkA-dependent cell wall integrity signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced,aberrant,no,Congo red; hygromycin B; H2O2,Congo red (CR): CHEBI:34653; H2O2: CAS:7722-84-1; hygromycin B: CHEBI:16976,,,,,gene deletion: full; gene complementation,,,RP,25687931,PubMed,10.1016/j.fgb.2015.02.006,Fungal Genet Biol. 2015 Feb 14;76:57-69,jinc@im.ac.cn,"Biochemical analyses revealed that deletion of thekexBgene resulted in impaired N-glycan processing, activation of the MpkA-dependent cell wall integrity signaling pathway, and ER-stress, as well as temperature sensitive cell wall defect.",J Wang 2015,2015,1 gene,Wang-2015-Kexin-like endoprotease KexB is requ,BATCH_046B,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5847,PHI:4604,UniProt,Q5HRC3,GenBank,AAW53705,,,RP62A,Sbp,,,,,,,1282,Staphylococcus epidermidis,,1457,chronic implant-associated infections,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,scaffold protein critical to biofilm formation,,,,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25799153,PubMed,10.1371/journal.ppat.1004735,PLoS Pathog. 2015 Mar 23;11(3):e1004735,rohde@uke.uni-hamburg.de,A mouse catheter infection-model was used,R Decker 2015,2015,1 gene,Decker-2015-An 18 kDa Scaffold Protein Is Crit,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5848,PHI:4605,UniProt,Q8F7S2,GenBank,AAN48071,,,56601,ColA,chromosome I,,,,,,173,Leptospira interrogans,57678,Lai,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,lung; liver; kidney,collagenase and critical virulence factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24277745,PubMed,10.1093/infdis/jit659,J Infect Dis. 2014 Apr 1;209(7):1105-15,med_bp@zju.edu.cn,,K Kassegne 2014,2014,1 gene,Kassegne-2014-Identification of collagenase as,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5849,PHI:4606,UniProt,Q8RYB2,GenBank,AAL11438,,,H30P04,PiGPB1,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Desirée,,,leaf,PiGPB1 is important for sporangia formation,,,phosphatase-mediated signalling,reduced virulence,,,,,,reduced,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25788734,PubMed,10.1093/jxb/erv094,J Exp Bot. 2015 Mar 18. pii: erv094,Sultana.Jahan@slu.se,,S N Jahan 2015,2015,1 gene,Jahan-2015-Plant-mediated gene silencing restr,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5850,PHI:4607,UniProt,A0A0B5JGW8,GenBank,AJG01371,,,,BxCYP33C9,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,88730,Pinus massoniana (related: chinese red pine),,,,leaf,cytochrome P450 genes,,,,reduced virulence,,,,,,,,,,no,abamectin; emamectin,abamectin: CHEBI:39214; emamectin: CHEBI:39230,,,,,altered gene expression / gene regulation: silencing,,,RP,25756378,PubMed,10.3390/ijms16035216,Int J Mol Sci. 2015 Mar 6;16(3):5216-34,Lhuang@njfu.edu.cn,Results indicated that the three cytochrome P450 genes may be involved in the resistance of B. xylophilus to pesticides,X Xu 2015,2015,3 genes,Xu-2015-Molecular Characterization and Functio,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5851,PHI:4608,UniProt,A0A0B5JJZ6,GenBank,AJG01372,,,,BxCYP33C4,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,88730,Pinus massoniana (related: chinese red pine),,,,leaf,cytochrome P450 genes,,,,reduced virulence,,,,,,,,,,no,abamectin; emamectin,abamectin: CHEBI:39214; emamectin: CHEBI:39230,,,,,altered gene expression / gene regulation: silencing,,,RP,25756378,PubMed,10.3390/ijms16035216,Int J Mol Sci. 2015 Mar 6;16(3):5216-34,Lhuang@njfu.edu.cn,Results indicated that the three cytochrome P450 genes may be involved in the resistance of B. xylophilus to pesticides,X Xu 2015,2015,3 genes,Xu-2015-Molecular Characterization and Functio,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5852,PHI:4609,UniProt,A0A0B5J4U6,GenBank,AJG01373,,,,BxCYP33D3,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,88730,Pinus massoniana (related: chinese red pine),,,,leaf,cytochrome P450 genes,,,,reduced virulence,,,,,,,,,,no,abamectin; emamectin,abamectin: CHEBI:39214; emamectin: CHEBI:39230,,,,,altered gene expression / gene regulation: silencing,,,RP,25756378,PubMed,10.3390/ijms16035216,Int J Mol Sci. 2015 Mar 6;16(3):5216-34,Lhuang@njfu.edu.cn,Results indicated that the three cytochrome P450 genes may be involved in the resistance of B. xylophilus to pesticides,X Xu 2015,2015,3 genes,Xu-2015-Molecular Characterization and Functio,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5853,PHI:4610,UniProt,A5IXN3,GenBank,CAL58792,,,PG2,pdhB,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,pyruvate dehyrogenase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,25799063,PubMed,10.1371/journal.pone.0119706,PLoS One. 2015 Mar 23;10(3):e0119706,Rohini.Chopra-Dewasthaly@vetmeduni.ac.at,,S Hegde 2015,2015,1 gene,Hegde-2015-Disruption of the pdhB Pyruvate Deh,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5854,PHI:4611,UniProt,Q18A49,GenBank,CAJ67687,,,630,Opp,,,,,,,1496,Clostridioides difficile,,,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,oligopeptide permeases,,,,increased virulence (hypervirulence),,,,,,increased,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25069979,PubMed,10.1128/IAI.02323-14,Infect Immun. 2014 Oct;82(10):4276-91,shonna.mcbride@emory.edu,Pathogen formerly called Clostridium difficile,A N Edwards 2014,2014,2 genes,Edwards-2014-Conserved Oligopeptide Permeases,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5855,PHI:4612,UniProt,A0A031WAR9,GenBank,CDS84968,,,,App,,,,,,,1496,Clostridioides difficile,,,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,oligopeptide permeases,,,,increased virulence (hypervirulence),,,,,,increased,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25069979,PubMed,10.1128/IAI.02323-14,Infect Immun. 2014 Oct;82(10):4276-91,shonna.mcbride@emory.edu,Pathogen formerly called Clostridium difficile,A N Edwards 2014,2014,2 genes,Edwards-2014-Conserved Oligopeptide Permeases,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5856,PHI:4613,UniProt,D0ZDL7,GenBank,ACY83722,,,EIB202,esaN,,"PPD130/91, in-frame deletion of esaN; deltaesaN",,,,,636,Edwardsiella tarda,,PPD130/91,hemorrhagic septicemia,bony fishes,96903,Trichopodus trichopterus (related: three spot gourami),,,,head kidney,type III secretion system,,,,increased virulence (hypervirulence),,,,,,increased,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24891103,PubMed,10.1128/IAI.01065-13,Infect Immun. 2014 Aug;82(8):3436-45,x.yu@imperial.ac.uk,,H Xie 2014,2014,2 genes,Xie-2014-Edwardsiella tarda-induced cytotoxici,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5857,PHI:4614,UniProt,A0A076LEI9,GenBank,AIJ06601,,,80813,fliC,,"PPD130/91, in-frame deletion of fliC; deltafliC",,,,,636,Edwardsiella tarda,,PPD130/91,hemorrhagic septicemia,bony fishes,96903,Trichopodus trichopterus (related: three spot gourami),,,,head kidney,flagellin,,,,increased virulence (hypervirulence),,,,,,increased,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24891103,PubMed,10.1128/IAI.01065-13,Infect Immun. 2014 Aug;82(8):3436-45,x.yu@imperial.ac.uk,,H Xie 2014,2014,2 genes,Xie-2014-Edwardsiella tarda-induced cytotoxici,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5858,PHI:4613,UniProt,D0ZDL7,GenBank,ACY83722,,,EIB202,esaN,,"PPD130/91, in-frame deletion of esaN; deltaesaN",,,,,636,Edwardsiella tarda,,PPD130/91,hemorrhagic septicemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,type III secretion system,,,,increased virulence (hypervirulence),,,,,,increased,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24891103,PubMed,10.1128/IAI.01065-13,Infect Immun. 2014 Aug;82(8):3436-45,x.yu@imperial.ac.uk,,H Xie 2014,2014,2 genes,Xie-2014-Edwardsiella tarda-induced cytotoxici,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5859,PHI:4614,UniProt,A0A076LEI9,GenBank,AIJ06601,,,80813,fliC,,"PPD130/91, in-frame deletion of fliC; deltafliC",,,,,636,Edwardsiella tarda,,PPD130/91,hemorrhagic septicemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,flagellin,,,,increased virulence (hypervirulence),,,,,,increased,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,24891103,PubMed,10.1128/IAI.01065-13,Infect Immun. 2014 Aug;82(8):3436-45,x.yu@imperial.ac.uk,,H Xie 2014,2014,2 genes,Xie-2014-Edwardsiella tarda-induced cytotoxici,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5860,PHI:4615,UniProt,P29138,GenBank,AAA33417,,,Me1,Pr1,,,,,,,5530,Metarhizium anisopliae,,CG 148,fungal keratitis,mites and ticks,6941,Rhipicephalus microplus (related: southern cattle tick),,,,larva,subtilisin-like protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25786608,PubMed,10.1007/s00436-015-4426-y,Parasitol Res. 2015 Mar 20,patriciagolo@gmail.com,Conidia with different levels of pr1 gene expression and enzymatic activity were obtained by producing them on either artificial medium (to yield low Pr1 activity) or onRhipicephalus micropluscadavers (to yield high Pr1 activity).,P S Golo 2015,2015,1 gene,Golo-2015-The influence of conidial Pr1 protea,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5861,PHI:4616,UniProt,G4N4N6,GenBank,EHA52051,,,70-15,MoSFA1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,S-(hydroxymethyl)glutathione dehydrogenase,,,,reduced virulence,,yes,,yes,,reduced,,reduced; aberrant,,no,NO; menadione; potassium superoxide; rose bengal; tert-butyl-hydroxyperoxide; H2O2,NO: CHEBI:16480; menadione: CHEBI:28869; potassium superoxide: CAS:12030-88-5; rose bengal: CHEBI:52261; tert-butyl-hydroxyperoxide: CHEBI:64090; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25793615,PubMed,10.1371/journal.pone.0120627,PLoS One. 2015 Mar 20;10(3):e0120627,sungc01@sina.com,"MoSFA1deletion mutants displayed hypersensitivity to different oxidants, reduced activities of superoxide dismutases and peroxidases, and lower glutathione content in cells, compared with the wild type.",Z Zhang 2015,2015,1 gene,Zhang-2015-An S-(Hydroxymethyl)Glutathione Deh,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5862,PHI:4617,UniProt,A0A0D3LXD4,GenBank,KF133976,,,YN07,PcPL1,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4072,Capsicum annuum (no common name found),06221 line,,,leaf,pectate lyase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5863,PHI:4618,UniProt,A0A0D3LX64,GenBank,KF133978,,,YN07,PcPL15,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4072,Capsicum annuum (no common name found),06221 line,,,leaf,pectate lyase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5864,PHI:4619,UniProt,A0A0D3LXF0,GenBank,KF133979,,,YN07,PcPL16,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4072,Capsicum annuum (no common name found),06221 line,,,leaf,pectate lyase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5865,PHI:4620,UniProt,A0A0D3LXG7,GenBank,KF133980,,,YN07,PcPL20,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4072,Capsicum annuum (no common name found),06221 line,,,leaf,pectate lyase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5866,PHI:4617,UniProt,A0A0D3LXD4,GenBank,KF133976,,,YN07,PcPL1,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4072,Capsicum annuum (no common name found),06221 line,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5867,PHI:4618,UniProt,A0A0D3LX64,GenBank,KF133978,,,YN07,PcPL15,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4072,Capsicum annuum (no common name found),06221 line,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5868,PHI:4619,UniProt,A0A0D3LXF0,GenBank,KF133979,,,YN07,PcPL16,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4072,Capsicum annuum (no common name found),06221 line,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5869,PHI:4620,UniProt,A0A0D3LXG7,GenBank,KF133980,,,YN07,PcPL20,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4072,Capsicum annuum (no common name found),06221 line,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5870,PHI:4617,UniProt,A0A0D3LXD4,GenBank,KF133976,,,YN07,PcPL1,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. NC89,,,leaf,pectate lyase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5871,PHI:4618,UniProt,A0A0D3LX64,GenBank,KF133978,,,YN07,PcPL15,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. NC89,,,leaf,pectate lyase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5872,PHI:4619,UniProt,A0A0D3LXF0,GenBank,KF133979,,,YN07,PcPL16,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. NC89,,,leaf,pectate lyase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5873,PHI:4620,UniProt,A0A0D3LXG7,GenBank,KF133980,,,YN07,PcPL20,,,,,,,4784,Phytophthora capsici,,SD33,vine blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. NC89,,,leaf,pectate lyase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25775270,PubMed,10.1094/MPMI-11-14-0352-R,Mol Plant Microbe Interact. 2015 Mar 16,zhxg@sdau.edu.cn,,Li Fu 2015,2015,4 genes,Fu-2015-Characterization of cell death-inducin,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5874,PHI:4621,UniProt,Q2FET1,GenBank,ABD22109,,,USA300_FPR3757,hysA,,AH1263deltahysA,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,hyaluronidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25069977,PubMed,10.1128/IAI.01710-14,Infect Immun. 2014 Oct;82(10):4253-64,alex-horswill@uiowa.edu,S. aureushyaluronidase is a CodY-regulated virulence factor,C B Ibberson 2014,2014,1 gene,Ibberson-2014-Staphylococcus aureus hyaluronid,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5875,PHI:4622,UniProt,N1J904,GenBank,CCU74273,,,DH14,CSEP0105,,,,Hsp16.9; Hsp17.5,"Hsp16.9, UniProt: F2DGA8; Hsp17.5, GenBank: AK250749",,34373,Blumeria graminis,62688,f. sp. hordei,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,putative effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25770154,PubMed,10.1104/pp.15.00278,Plant Physiol. 2015 Mar 13. pii: pp.00278.2015,htc@plen.ku.dk,CSEP0105 promotes virulence by interfering with the chaperone activity of barley small heat shock proteins essential for defense and stress responses.,A A Ahmed 2015,2015,2 genes,Ahmed-2015-Barley Powdery Mildew Effector Cand,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5876,PHI:4623,UniProt,N1JPG4,GenBank,CCU82600,,,DH14,CSEP0162,,,,Hsp16.9; Hsp17.5,"Hsp16.9, UniProt: F2DGA8; Hsp17.5, GenBank: AK250749",,34373,Blumeria graminis,62688,f. sp. hordei,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,putative effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25770154,PubMed,10.1104/pp.15.00278,Plant Physiol. 2015 Mar 13. pii: pp.00278.2015,htc@plen.ku.dk,"Candidate Secreted Effector Proteins (CSEPs), CSEP0105 and CSEP0162, which contribute to pathogen success and appear to be required during or after haustorial formation.",A A Ahmed 2015,2015,2 genes,Ahmed-2015-Barley Powdery Mildew Effector Cand,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5877,PHI:4624,UniProt,Q9JP55,GenBank,AAF43620,,,PeruGJ6,cagA,,,,,,,210,Helicobacter pylori,290847,51B,gastric infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,stomach,effector protein,,,p38 MAPK pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25807464,PubMed,10.1371/journal.pone.0121841,PLoS One. 2015 Mar 25;10(3):e0121841,vreyes@utmb.edu,"H. pylori T4SS components activate the p38 MAPK pathway, upregulate B7-H1 expression by GEC, and cause Treg cell induction; thus, contribute to establishing a persistent infection characteristic of H.pylori.",T T Lina 2015,2015,1 gene,Lina-2015-Helicobacter pylori cag Pathogenicit,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5878,PHI:4625,UniProt,Q6FIU2,GenBank,CAG62832,,,CBS 138,CgHog1,chromosome M,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; kidney; liver; spleen,stress-responsive mitogen-activated protein kinases,,,mitogen-activated protein kinase signaling pathways,reduced virulence,,,,,,,,wild type,,no,fluconazole,"fluconazole: CHEBI:46081, CAS:86386-73-4",,,,,gene deletion: full; gene complementation,,,RP,25772226,PubMed,10.1111/febs.13264,FEBS J. 2015 Mar 13,rkaur@cdfd.org.in,"The Cgslt2deltamutant exhibited elevated sensitivity to fluconazole antifungal (Fig. 2B). However, fluconazole had no effect on growth of the Cghog1deltamutant",V K Srivastava 2015,2015,2 genes,Srivastava-2015-The mitogen-activated protein,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5879,PHI:4626,UniProt,Q6FPF2,GenBank,CAG60841,,,CBS 138,CgSlt2,chromosome J,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; kidney; liver; spleen,stress-responsive mitogen-activated protein kinases,,,mitogen-activated protein kinase signaling pathways,unaffected pathogenicity,,,,,,,,wild type,,no,fluconazole,"fluconazole: CHEBI:46081, CAS:86386-73-4",,,,,gene deletion: full; gene complementation,,,RP,25772226,PubMed,10.1111/febs.13264,FEBS J. 2015 Mar 13,rkaur@cdfd.org.in,"The Cgslt2deltamutant exhibited elevated sensitivity to fluconazole antifungal (Fig. 2B). However, fluconazole had no effect on growth of the Cghog1deltamutant",V K Srivastava 2015,2015,2 genes,Srivastava-2015-The mitogen-activated protein,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5880,PHI:4627,UniProt,Q8PHN8,GenBank,AAM38055,,,306,otsA,,,,,,,346,Xanthomonas citri,611301,subsp. citri strain Xcc99-1330,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,trehalose-6-phosphate synthase,,,trehalose biosynthetic pathways,reduced virulence,,,,,,,,,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,RP,25770587,PubMed,10.1093/jxb/erv095,J Exp Bot. 2015 Mar 14. pii: erv095,gottig@ibr-conicet.gov.ar,"Mutants were less resistant to salt and oxidative stresses, and was less able to colonize plant tissues.",A Piazza 2015,2015,1 gene,Piazza-2015-The dual nature of trehalose in ci,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5881,PHI:4628,,no data found,,,,,,Cfp4,,ura5-32deltacfp4-1::T-DNA(hph),,,,,5037,Histoplasma capsulatum,447093,G186A,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,culture filtrate protein 4,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25114108,PubMed,10.1128/IAI.01893-14,Infect Immun. 2014 Oct;82(10):4414-25,rappleye.1@osu.edu,Cfp4-deficient strains are not attenuated in virulence in human macrophages or during lung infection in a murine model of histoplasmosis.,E D Holbrook 2014,2014,1 gene,Holbrook-2014-Glycosylation and immunoreactivi,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5882,PHI:4629,UniProt,E2QL90,GenBank,AFK73424,,,DE205B,IbeR,GimA genomic island,deltaibeR (ibeR mutant in DE205B),,,,,562,Escherichia coli,,DE205B,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),ICR,,,blood; brain; lung; liver; spleen,IbeR controlled expression of stress-resistance genes and virulence genes.,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,RP,25768126,PubMed,10.1371/journal.pone.0119698,PLoS One. 2015 Mar 13;10(3):e0119698,daijianjun@njau.edu.cn,,S Wang 2015,2015,1 gene,Wang-2015-IbeR Facilitates Stress-Resistance,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5883,PHI:4630,UniProt,P11989,GenBank,AAA23509,,,K12,PafR,metV genomic island,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney; spleen,transcription regulator,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25069986,PubMed,10.1128/IAI.00086-14,Infect Immun. 2014 Oct;82(10):4241-52,ornaam@ekmd.huji.ac.il,,M Baum 2014,2014,2 genes,"Baum-2014-PafR, a novel transcription regulato",BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5884,PHI:4631,UniProt,P19642,GenBank,AAA24098,,,K12,pafP,metV genomic island,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney; spleen,transcription regulator,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25069986,PubMed,10.1128/IAI.00086-14,Infect Immun. 2014 Oct;82(10):4241-52,ornaam@ekmd.huji.ac.il,,M Baum 2014,2014,2 genes,"Baum-2014-PafR, a novel transcription regulato",BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5885,PHI:4630,UniProt,P11989,GenBank,AAA23509,,,K12,PafR,metV genomic island,,,,,PHI:4631,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney; spleen,transcription regulator,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25069986,PubMed,10.1128/IAI.00086-14,Infect Immun. 2014 Oct;82(10):4241-52,ornaam@ekmd.huji.ac.il,,M Baum 2014,2014,2 genes,"Baum-2014-PafR, a novel transcription regulato",BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5886,PHI:4631,UniProt,P19642,GenBank,AAA24098,,,K12,pafP,metV genomic island,,,,,PHI:4630,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney; spleen,transcription regulator,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25069986,PubMed,10.1128/IAI.00086-14,Infect Immun. 2014 Oct;82(10):4241-52,ornaam@ekmd.huji.ac.il,,M Baum 2014,2014,2 genes,"Baum-2014-PafR, a novel transcription regulato",BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5887,PHI:4632,UniProt,C5A8V0,GenBank,ACR27379,,,BGR1,flhD,chromosome 1,,,,,,337,Burkholderia glumae,1417989,336gr-1,bacterial panicle blight (rice),monocots,4679,Allium cepa (related: onion),,,,bulb,flagellar transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25806356,PubMed,10.3389/fcimb.2015.00022,Front Cell Infect Microbiol. 2015 Mar 10;5:22,jham@agcenter.lsu.edu,,R Chen 2015,2015,5 genes,Chen-2015-Identification of potential genetic,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5888,PHI:4633,UniProt,C5A8Z0,GenBank,ACR27419,,,BGR1,dgcB,chromosome 1,,,,,,337,Burkholderia glumae,1417989,336gr-1,bacterial panicle blight (rice),monocots,4679,Allium cepa (related: onion),,,,bulb,diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25806356,PubMed,10.3389/fcimb.2015.00022,Front Cell Infect Microbiol. 2015 Mar 10;5:22,jham@agcenter.lsu.edu,,R Chen 2015,2015,5 genes,Chen-2015-Identification of potential genetic,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5889,PHI:4634,UniProt,C5ACT8,GenBank,ACR30053,,,BGR1,wzyB,chromosome 1,,,,,,337,Burkholderia glumae,1417989,336gr-1,bacterial panicle blight (rice),monocots,4679,Allium cepa (related: onion),,,,bulb,O-antigen polymerase family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25806356,PubMed,10.3389/fcimb.2015.00022,Front Cell Infect Microbiol. 2015 Mar 10;5:22,jham@agcenter.lsu.edu,,R Chen 2015,2015,5 genes,Chen-2015-Identification of potential genetic,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5890,PHI:4635,UniProt,A4KCQ2,GenBank,ABL59968,,,BGR1,qsmR,,,,,,,337,Burkholderia glumae,1417989,336gr-1,bacterial panicle blight (rice),monocots,4679,Allium cepa (related: onion),,,,bulb,IclR-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25806356,PubMed,10.3389/fcimb.2015.00022,Front Cell Infect Microbiol. 2015 Mar 10;5:22,jham@agcenter.lsu.edu,,R Chen 2015,2015,5 genes,Chen-2015-Identification of potential genetic,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5891,PHI:4636,UniProt,C5AML7,GenBank,ACR31068,,,BGR1,toxK,chromosome 2,,,,,,337,Burkholderia glumae,1417989,336gr-1,bacterial panicle blight (rice),monocots,4679,Allium cepa (related: onion),,,,bulb,toxoflavin biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25806356,PubMed,10.3389/fcimb.2015.00022,Front Cell Infect Microbiol. 2015 Mar 10;5:22,jham@agcenter.lsu.edu,,R Chen 2015,2015,5 genes,Chen-2015-Identification of potential genetic,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5892,PHI:4637,UniProt,Q180C8,GenBank,CAJ70181,,,630,CD3284,,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,HtrA-like protease,,,,increased virulence (hypervirulence),,,,,,reduced,,,,no,,,,,,,gene mutation,,,RP,25047848,PubMed,10.1128/IAI.02336-14,Infect Immun. 2014 Oct;82(10):4222-32,W.K.Smits@LUMC.n,Pathogen formerly called Clostridium difficile,D Bakker 2014,2014,1 gene,Bakker-2014-The HtrA-like protease CD3284 modu,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5893,PHI:4638,UniProt,W9MSF5,GenBank,EWZ94942,,,MN25,Fbp1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,root,F-box protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,sodium dodecyl sulfate (SDS); calcofluor white (CFW),sodium dodecyl sulfate (SDS): CHEBI:8984; calcofluor white (CFW): CHEBI:50011,,,,,gene mutation,,,RP,25808603,PubMed,10.1111/mpp.12259,Mol Plant Pathol. 2015 Mar 25,ge1hedic@uco.es,,C Miguel-Rojas 2015,2015,1 gene,Miguel-Rojas-2015-The F-box protein Fbp1 funct,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5894,PHI:4638,,no data found,,,,,,MoMsb2,,,,Ras2,UniProt: G4N1S3,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,signaling mucin,,,Pmk1 pathway,reduced virulence,,yes,,yes,,reduced,,,,no,,,,,,,gene mutation,,,RP,25808678,PubMed,10.1111/1462-2920.12847,Environ Microbiol. 2015 Mar 23,jinrong@purdue.edu,,G Wang 2015,2015,2 genes,Wang-2015-Activation of the signaling mucin Mo,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5895,PHI:4638,,no data found,,,,,,MoMsb2,,,,Ras2,UniProt: G4N1S3,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,signaling mucin,,,Pmk1 pathway,reduced virulence,,yes,,yes,,reduced,,,,no,,,,,,,gene mutation,,,RP,25808678,PubMed,10.1111/1462-2920.12847,Environ Microbiol. 2015 Mar 23,jinrong@purdue.edu,,G Wang 2015,2015,2 genes,Wang-2015-Activation of the signaling mucin Mo,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5896,PHI:4639,UniProt,Q8WZJ0,,,,,,Cbp1,,,,,,PHI:4638,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mucin,,,Pmk1 pathway,loss of pathogenicity,,yes,,yes,,reduced,,,,no,,,,,,,gene deletion: full,,,RP,25808678,PubMed,10.1111/1462-2920.12847,Environ Microbiol. 2015 Mar 23,jinrong@purdue.edu,,G Wang 2015,2015,2 genes,Wang-2015-Activation of the signaling mucin Mo,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5897,PHI:4639,UniProt,Q8WZJ0,,,,,,Cbp1,,,,,,PHI:4638,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,mucin,,,Pmk1 pathway,loss of pathogenicity,,yes,,yes,,reduced,,,,no,,,,,,,gene deletion: full,,,RP,25808678,PubMed,10.1111/1462-2920.12847,Environ Microbiol. 2015 Mar 23,jinrong@purdue.edu,,G Wang 2015,2015,2 genes,Wang-2015-Activation of the signaling mucin Mo,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5898,PHI:4640,UniProt,J9VN27,GenBank,AFR95653,,,H99,VPS27,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,endosomal sorting complex,,,,loss of pathogenicity,,,,,,,,reduced,,no,NaCl; LiCl; KCl; CaCl2,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; CaCl2: CHEBI:3312,,,,,gene mutation,,,RP,25732100,PubMed,10.1111/mmi.12985,Mol Microbiol. 2015 Mar 2,kronstad@msl.ubc.ca,Mutants are defective in salt tolerance,G Hu 2015,2015,6 genes,Hu-2015-The endosomal sorting complex required,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5899,PHI:4641,UniProt,J9VNI3,GenBank,AFR96022,,,H99,VPS22,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,endosomal sorting complex,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,NaCl; LiCl; KCl; CaCl2,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; CaCl2: CHEBI:3312,,,,,gene mutation,,,RP,25732100,PubMed,10.1111/mmi.12985,Mol Microbiol. 2015 Mar 2,kronstad@msl.ubc.ca,Mutants are defective in salt tolerance,G Hu 2015,2015,6 genes,Hu-2015-The endosomal sorting complex required,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5900,PHI:4642,UniProt,J9VKA8,GenBank,AFR94877,,,H99,VPS20,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,endosomal sorting complex,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,NaCl; LiCl; KCl; CaCl2,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; CaCl2: CHEBI:3312,,,,,gene mutation,,,RP,25732100,PubMed,10.1111/mmi.12985,Mol Microbiol. 2015 Mar 2,kronstad@msl.ubc.ca,Mutants are defective in salt tolerance,G Hu 2015,2015,6 genes,Hu-2015-The endosomal sorting complex required,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5901,PHI:4643,UniProt,J9VU41,GenBank,AFR97788,,,H99,SNF7,,,,BRO1,UniProt: J9VQ47,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,endosomal sorting complex,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,NaCl; LiCl; KCl; CaCl2,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; CaCl2: CHEBI:3312,,,,,gene mutation,,,RP,25732100,PubMed,10.1111/mmi.12985,Mol Microbiol. 2015 Mar 2,kronstad@msl.ubc.ca,Mutants are defective in salt tolerance,G Hu 2015,2015,6 genes,Hu-2015-The endosomal sorting complex required,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5902,PHI:4644,UniProt,J9VX80,GenBank,AFR97229,,,H99,VPS4,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,endosomal sorting complex,,,,loss of pathogenicity,,,,,,,,wild type,,no,NaCl; LiCl; KCl; CaCl2,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; CaCl2: CHEBI:3312,,,,,gene mutation,,,RP,25732100,PubMed,10.1111/mmi.12985,Mol Microbiol. 2015 Mar 2,kronstad@msl.ubc.ca,Mutants are defective in salt tolerance,G Hu 2015,2015,6 genes,Hu-2015-The endosomal sorting complex required,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5903,PHI:4645,UniProt,J9W1H7,GenBank,AFR98859,,,H99,Rim101,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,endosomal sorting complex,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,NaCl; LiCl; KCl; CaCl2,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; CaCl2: CHEBI:3312,,,,,gene mutation,,,RP,25732100,PubMed,10.1111/mmi.12985,Mol Microbiol. 2015 Mar 2,kronstad@msl.ubc.ca,Mutants are defective in salt tolerance,G Hu 2015,2015,6 genes,Hu-2015-The endosomal sorting complex required,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5904,PHI:4646,,no data found,,CD20291_1457,,,,PtsM,,,,,,,1496,Clostridioides difficile,,RT027,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,bacteriocin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25805733,PubMed,10.1128/mBio.02368-14,MBio. 2015 Mar 24;6(2). pii: e02368-14,greg@avidbiotics.com,"The modified diffocins were stable and killed all 16 tested BI/NAP1/027-type strains. Administered in drinking water, they survived passage through the mouse gastrointestinal (GI) tract, did not detectably alter the mouse gut microbiota or disrupt natural colonization resistance to C. difficileor the vancomycin-resistantEnterococcus faecium(VREF), and prevented antibiotic-induced colonization of mice inoculated with BI/NAP1/027-type spores. Pathogen formerly called Clostridium difficile",D Gebhart 2015,2015,1 gene,Gebhart-2015-A Modified R-Type Bacteriocin Spe,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5905,PHI:4647,UniProt,Q7BCK4,GenBank,YP_009078435,,,,IcsA,,,,,,,623,Shigella flexneri,1086030,M90T,shigellosis,rodents,10090,Mus musculus (related: house mouse),,,,eye,adhesin regulated by the type III secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,24721572,PubMed,10.1016/j.chom.2014.03.001,Cell Host Microbe. 2014 Apr 9;15(4):435-45,zychlinsky@mpiib-berlin.mpg.de,"IcsA-dependent adhesion contributes to virulence in a mouse model of shigellosis, underscoring the importance of this adhesin toS. Flexneri pathogenesis",A B Zumsteg 2014,2014,1 gene,Brotcke Zumsteg-2014-IcsA is a Shigella flexne,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5906,PHI:4648,UniProt,A0A077XHZ4,GenBank,CDS48689,,,ANKA,PbPL,,,,,,,5821,Plasmodium berghei,,,malaria,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver,phospholipase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25786000,PubMed,10.1371/journal.ppat.1004760,PLoS Pathog. 2015 Mar 18;11(3):e1004760,burda@izb.unibe.ch,"PbPL-deficient parasites exhibit impaired PVM (parasitophorous vacuole membrane) rupture, resulting in delayed parasite egress.",P Burda 2015,2015,1 gene,Burda-2015-A Plasmodium phospholipase is invol,BATCH_047A,2015-04-01,MC,,,,,,,,,,,,,
,,Record 5907,PHI:4649,UniProt,Q5GZN6,GenBank,AAW75835,,,KACC 10331,fliC,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,flagellar motility,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25617720,PubMed,10.1016/j.molp.2015.01.012,Mol Plant. 2015 Jan 21. pii: S1674-2052(15)00099-4,wxs@cau.edu.cn,Rice OsFLS2-Mediated Perception of Bacterial Flagellins Is Evaded byXanthomonas oryzae pvs.Oryzae and oryzicola.,S Wang 2015,2015,3 genes,Wang-2015-Rice OsFLS2-mediated perception of b,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5908,PHI:4650,UniProt,G7TFG0,GenBank,AEQ96517,,,BLS256,fliC,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,flagellar motility,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25617720,PubMed,10.1016/j.molp.2015.01.012,Mol Plant. 2015 Jan 21. pii: S1674-2052(15)00099-4,,Rice OsFLS2-Mediated Perception of Bacterial Flagellins Is Evaded byXanthomonas oryzae pvs.Oryzae and oryzicola.,S Wang 2015,2015,3 genes,Wang-2015-Rice OsFLS2-mediated perception of b,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5909,PHI:4651,UniProt,G7T9L2,GenBank,AEQ94671,,,BLS256,rbfC,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,glycosyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25617720,PubMed,10.1016/j.molp.2015.01.012,Mol Plant. 2015 Jan 21. pii: S1674-2052(15)00099-4,wxs@cau.edu.cn,Rice OsFLS2-Mediated Perception of Bacterial Flagellins Is Evaded byXanthomonas oryzae pvs.Oryzae and oryzicola.,S Wang 2015,2015,3 genes,Wang-2015-Rice OsFLS2-mediated perception of b,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5910,PHI:4649,UniProt,Q5GZN6,GenBank,AAW75835,,,KACC 10331,fliC,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Jingang 30,,,leaf,flagellar motility,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25617720,PubMed,10.1016/j.molp.2015.01.012,Mol Plant. 2015 Jan 21. pii: S1674-2052(15)00099-4,wxs@cau.edu.cn,Rice OsFLS2-Mediated Perception of Bacterial Flagellins Is Evaded byXanthomonas oryzae pvs.Oryzae and oryzicola.,S Wang 2015,2015,3 genes,Wang-2015-Rice OsFLS2-mediated perception of b,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5911,PHI:4650,UniProt,G7TFG0,GenBank,AEQ96517,,,BLS256,fliC,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Jingang 30,,,leaf,flagellar motility,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25617720,PubMed,10.1016/j.molp.2015.01.012,Mol Plant. 2015 Jan 21. pii: S1674-2052(15)00099-4,,Rice OsFLS2-Mediated Perception of Bacterial Flagellins Is Evaded byXanthomonas oryzae pvs.Oryzae and oryzicola.,S Wang 2015,2015,3 genes,Wang-2015-Rice OsFLS2-mediated perception of b,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5912,PHI:4651,UniProt,G7T9L2,GenBank,AEQ94671,,,BLS256,rbfC,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Jingang 30,,,leaf,glycosyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25617720,PubMed,10.1016/j.molp.2015.01.012,Mol Plant. 2015 Jan 21. pii: S1674-2052(15)00099-4,wxs@cau.edu.cn,Rice OsFLS2-Mediated Perception of Bacterial Flagellins Is Evaded byXanthomonas oryzae pvs.Oryzae and oryzicola.,S Wang 2015,2015,3 genes,Wang-2015-Rice OsFLS2-mediated perception of b,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5913,PHI:4652,UniProt,Q1JLQ2,GenBank,ABF32167,,,,MntE,,,,,,,1314,Streptococcus pyogenes,,5448,infection,rodents,10090,Mus musculus (related: house mouse),B6;SJLJ-Tg(Alb-PLG)1Dgi/Uqah,,,,manganese homeostasis,,,,unaffected pathogenicity,,,,,,,,,,no,Mg; H202,H2O2: CHEBI:16240; Mg: CHEBI:18420,,,,,gene mutation; gene complementation,,,RP,25805729,PubMed,10.1128/mBio.00278-15,MBio. 2015 Mar 24;6(2). pii: e00278-15,mark.walker@uq.edu.au,The mutants were less efficient in surviving neutrophils; the mutants were also more sensitive to Mg and oxidative stress.,A G Turner 2015,2015,1 gene,Turner-2015-Manganese homeostasis in group a s,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5914,PHI:4653,UniProt,Q99SP5,GenBank,BAB43084,,,N315,SA1804,,,,,,,1280,Staphylococcus aureus,875057,923,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25806024,PubMed,10.3389/fmicb.2015.00174,Front Microbiol. 2015 Mar 9;6:174,jixxx002@umn.edu,,J Yang 2015,2015,2 genes,Yang-2015-The novel transcriptional regulator,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5915,PHI:4654,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,PHI:4655,1280,Staphylococcus aureus,875057,923,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"controls expression of important virulence factors, including toxins and invasins",,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25806024,PubMed,10.3389/fmicb.2015.00174,Front Microbiol. 2015 Mar 9;6:174,jixxx002@umn.edu,,J Yang 2015,2015,2 genes,Yang-2015-The novel transcriptional regulator,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5916,PHI:4655,UniProt,Q2G2U1,GenBank,CAD89115,,,ISP479C,saeS,,,,,,PHI:4654,1280,Staphylococcus aureus,875057,923,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"controls expression of important virulence factors, including toxins and invasins",,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25806024,PubMed,10.3389/fmicb.2015.00174,Front Microbiol. 2015 Mar 9;6:174,jixxx002@umn.edu,,J Yang 2015,2015,2 genes,Yang-2015-The novel transcriptional regulator,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5917,PHI:4653,UniProt,Q99SP5,GenBank,BAB43084,,,N315,SA1804,,,,,,PHI:4654; PHI:4655,1280,Staphylococcus aureus,875057,923,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25806024,PubMed,10.3389/fmicb.2015.00174,Front Microbiol. 2015 Mar 9;6:174,jixxx002@umn.edu,,J Yang 2015,2015,2 genes,Yang-2015-The novel transcriptional regulator,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5918,PHI:4654,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,PHI:4653; PHI:4655,1280,Staphylococcus aureus,875057,923,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"controls expression of important virulence factors, including toxins and invasins",,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25806024,PubMed,10.3389/fmicb.2015.00174,Front Microbiol. 2015 Mar 9;6:174,jixxx002@umn.edu,,J Yang 2015,2015,2 genes,Yang-2015-The novel transcriptional regulator,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5919,PHI:4655,UniProt,Q2G2U1,GenBank,CAD89115,,,ISP479C,saeS,,,,,,PHI:4653; PHI:4654,1280,Staphylococcus aureus,875057,923,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"controls expression of important virulence factors, including toxins and invasins",,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25806024,PubMed,10.3389/fmicb.2015.00174,Front Microbiol. 2015 Mar 9;6:174,jixxx002@umn.edu,,J Yang 2015,2015,2 genes,Yang-2015-The novel transcriptional regulator,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5920,PHI:4656,UniProt,Q59R32,GenBank,EAK92921,,,SC5314,orf19.6688,chromosome 7,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,bipartite nuclear localization signal,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,24610660,PubMed,10.1128/EC.00051-14,Eukaryot Cell. 2014 Aug;13(8):977-89,Duncan.Wilson@abdn.ac.uk,,D Wilson 2014,2014,2 genes,Wilson-2014-Candida albicans specific genes_ d,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5921,PHI:4657,UniProt,Q5AHE8,GenBank,EAL02152,,,SC5314,pga16,chromosome 2,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,virulence factor,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,24610660,PubMed,10.1128/EC.00051-14,Eukaryot Cell. 2014 Aug;13(8):977-89,Duncan.Wilson@abdn.ac.uk,,D Wilson 2014,2014,2 genes,Wilson-2014-Candida albicans specific genes_ d,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5922,PHI:4658,UniProt,I1RAH1,GenBank,ESU05689,,,PH-1,FgHXK1,chromosome 1,,,,,,5518,Fusarium graminearum,,2021,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,hexokinase,,,,reduced virulence,,,,,,reduced; aberrant,wild type,reduced,aberrant,no,carbendazim; congo red; SDS; NaCl; KCl; caffeine,"carbendazim: CHEBI:3392, CAS:10605-21-7; congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; caffeine: CHEBI:27732",,,,,gene deletion: full; gene complementation,,,RP,25808544,PubMed,10.1111/mpp.12258,Mol Plant Pathol. 2015 Mar 22,mgzhou@njau.edu.cn,Sensitivity tests to MBC and various stresses indicated that both deltaFgHXK1 and deltaFgHXK2 mutants showed no significant difference with parental strains,L Zhang 2015,2015,2 genes,Zhang-2015-Hexokinase plays a critical role in,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5923,PHI:4659,UniProt,I1RGY2,GenBank,ESU10275,,,PH-1,FgHXK2,chromosome 2,,,,,,5518,Fusarium graminearum,,2021,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,stigma,hexokinase,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,wild type,no,carbendazim; congo red; SDS; NaCl; KCl; caffeine,"carbendazim: CHEBI:3392, CAS:10605-21-7; congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; caffeine: CHEBI:27732",,,,,gene deletion: full; gene complementation,,,RP,25808544,PubMed,10.1111/mpp.12258,Mol Plant Pathol. 2015 Mar 22,mgzhou@njau.edu.cn,Sensitivity tests to MBC and various stresses indicated that both deltaFgHXK1 and deltaFgHXK2 mutants showed no significant difference with parental strains,L Zhang 2015,2015,2 genes,Zhang-2015-Hexokinase plays a critical role in,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5924,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,,,,Lethal pathogen phenotype,,,,chitin synthases,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,,W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5925,PHI:4661,UniProt,Q96VK1,GenBank,CAC41026,,,,Chs2,,,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Sumai 3,,,spike,chitin synthases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,,W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5926,PHI:4661,UniProt,Q96VK1,GenBank,CAC41026,,,,Chs2,,,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,spike,chitin synthases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,,W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5927,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-1,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Sumai 3,,,seedling,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5928,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-3,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Sumai 3,,,seedling,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5929,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-5,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Sumai 3,,,seedling,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5930,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-1,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Sumai 3,,,floret,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5931,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-3,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Sumai 3,,,floret,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5932,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-5,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Sumai 3,,,floret,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5933,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-1,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,seedling,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5934,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-3,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,seedling,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5935,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-5,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,seedling,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5936,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-1,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,floret,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5937,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-3,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,floret,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5938,PHI:4660,UniProt,I1S097,GenBank,ESU16792,,,PH-1,Chs3b,,Chs3bRNAi-5,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,floret,chitin synthases,,,,reduced virulence,,,,,,,,defective,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25735638,PubMed,10.1111/pbi.12352,Plant Biotechnol J. 2015 Mar 4,yucailiao@mail.hzau.edu.cn,"Also the presence of each of the three specific short interfering RNAs (Chs3bRNAi-1, Chs3bRNAi-3 or Chs3bRNAi-5) in transgenic wheat plants profoundly restricted the growth of pathogenic mycelia",W Cheng 2015,2015,2 genes,Cheng-2015-Host-induced gene silencing of an e,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5939,PHI:4662,UniProt,D7HUV5,GenBank,EFI01223,,,NCPPB 3335,DgcP,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,diguanylate cyclase,,,c-di-GMP signalling pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25809128,PubMed,10.1111/1462-2920.12856,Environ Microbiol. 2015 Mar 25,crr@uma.es,,I M Aragon 2015,2015,2 genes,Aragon-2015-Diguanylate cyclase DgcP is involv,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5940,PHI:4663,UniProt,S0JAX7,GenBank,AIS22451,,,PAK,DgcP,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,diguanylate cyclase,,,c-di-GMP signalling pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25809128,PubMed,10.1111/1462-2920.12856,Environ Microbiol. 2015 Mar 25,crr@uma.es,,I M Aragon 2015,2015,2 genes,Aragon-2015-Diguanylate cyclase DgcP is involv,BATCH_047B,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5941,PHI:4664,UniProt,Q63LQ1,GenBank,CAH38424,,,K96243,bcaA,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5942,PHI:4665,UniProt,Q63M66,GenBank,CAH38256,,,K96243,boaA,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5943,PHI:4666,UniProt,Q63UB0,GenBank,CAH35703,,,K96243,boaB,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5944,PHI:4667,UniProt,Q63KC6,GenBank,CAH38909,,,K96243,bpaA,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5945,PHI:4668,UniProt,Q63UH1,GenBank,CAH35630,,,K96243,bpaC,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5946,PHI:4669,UniProt,Q63LV4,GenBank,CAH38370,,,K96243,bpaE,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5947,PHI:4670,UniProt,Q63KC3,GenBank,CAH38912,,,K96243,bpaF,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5948,PHI:4671,UniProt,Q63K73,GenBank,CAH38965,,,K96243,bimA,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5949,PHI:4671,UniProt,Q63K73,GenBank,CAH38965,,,K96243,bimA,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774.2 cell line,,,macrophage,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5950,PHI:4666,UniProt,Q63UB0,GenBank,CAH35703,,,K96243,boaB,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774.2 cell line,,,macrophage,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5951,PHI:4668,UniProt,Q63UH1,GenBank,CAH35630,,,K96243,bpaC,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774.2 cell line,,,macrophage,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5952,PHI:4669,UniProt,Q63LV4,GenBank,CAH38370,,,K96243,bpaE,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774.2 cell line,,,macrophage,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,25830295,PubMed,10.1371/journal.pone.0121271,PLoS One. 2015 Apr 1;10(4):e0121271,eg98@leicester.ac.uk,,N R L Adler 2015,2015,8 genes,Lazar Adler-2015-Systematic Mutagenesis of Gen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5953,PHI:4672,UniProt,Q4WBL9,GenBank,EAL84893,,,Af293,AmcA,chromosome 8,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative mitochondrial ornithine transporter,,,,unaffected pathogenicity,,,,,,,,reduced,,no,eflornithine,eflornithine: CHEBI:4762,,,,,gene mutation; gene complementation,,,RP,25904899,PubMed,10.3389/fmicb.2015.00252,Front Microbiol. 2015 Apr 7;6:252,hubertus.haas@i-med.ac.at,AmcA-deficiency increased the susceptibility of A. fumigatus to the polyamine biosynthesis inhibitor eflornithine and reduced growth particularly on ornithine as the sole nitrogen source during iron starvation and sufficiency.,L Schafferer 2015,2015,1 gene,Schafferer-2015-AmcA-a putative mitochondrial,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5954,PHI:4673,UniProt,A3MZG1,GenBank,ABN73547,,,L20,Apa1,,,,,,,715,Actinobacillus pleuropneumoniae,416269,serotype 5b strain L20,pleuropneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),,,,lung,autotransporter adhesin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25818350,PubMed,10.1016/j.vetmic.2015.02.026,Vet Microbiol. 2015 May 15;177(1-2):175-83,leilc@jlu.edu.cn,,L Wang 2015,2015,1 gene,Wang-2015-The Adh adhesin domain is required f,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5955,PHI:4674,UniProt,P9WKX3,GenBank,CCP46609,,,H37Rv,Rv3780,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,proteasome activator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25831519,PubMed,10.1073/pnas.1423319112,Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1763-72,heran.darwin@med.nyu.edu,"Rv3780 promoted robust degradation of the heat shock protein repressor, HspR. Rv3780 mutant had a general growth defect, was sensitive to heat stress, and was attenuated for growth in mice.",J B Jastrab 2015,2015,1 gene,Jastrab-2015-An adenosine triphosphate-indepen,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5956,PHI:4675,UniProt,B2HI84,GenBank,ACC38510,,,M,MMAR_0039,,,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,N-alpha-terminal acetyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25135684,PubMed,10.1128/IAI.02153-14,Infect Immun. 2014 Nov;82(11):4572-86,pchampio@nd.edu,There is an inverse relationship between EsxA acetylation and virulence.,F M Medie 2014,2014,1 gene,Medie-2014-Homeostasis of N-alpha terminal ace,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5957,PHI:4676,UniProt,P35347,GenBank,CAA51053,,,,CRH,,,,,,,1313,Streptococcus pneumoniae,,6301,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,peptide hormone involved in stress,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25904910,PubMed,10.3389/fmicb.2015.00279,Front Microbiol. 2015 Apr 8;6:279,harlan.jones@unthsc.edu,"Mice were infected with CRH-treated S. pneumoniaevia intranasal route, showing an increase in pulmonary bacterial burden.",C G N Ndjom 2015,2015,1 gene,Ndjom-2015-CRH promotes S. pneumoniae growth i,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5958,PHI:4677,UniProt,B0Y4S0,GenBank,EDP50669,,,A1163,AfcpcB,,,,,,,746128,Aspergillus fumigatus,,A1160,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,governs growth and development,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,25892048,PubMed,10.1016/j.fgb.2015.04.007,Fungal Genet Biol. 2015 Apr 16. pii: S1087-1845(15)00073-0,linglu@njnu.edu.cn,,Z Cai 2015,2015,2 genes,Cai-2015-The Gbeta-like protein CpcB is requir,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5959,PHI:4678,UniProt,B0XR79,GenBank,EDP56530,,,A1163,AfgpaB,,,,,,PHI:4677,746128,Aspergillus fumigatus,,A1160,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,governs growth and development,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,25892048,PubMed,10.1016/j.fgb.2015.04.007,Fungal Genet Biol. 2015 Apr 16. pii: S1087-1845(15)00073-0,linglu@njnu.edu.cn,,Z Cai 2015,2015,2 genes,Cai-2015-The Gbeta-like protein CpcB is requir,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5960,PHI:4677,UniProt,B0Y4S0,GenBank,EDP50669,,,A1163,AfcpcB,,,,,,PHI:4678,746128,Aspergillus fumigatus,,A1160,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,governs growth and development,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,25892048,PubMed,10.1016/j.fgb.2015.04.007,Fungal Genet Biol. 2015 Apr 16. pii: S1087-1845(15)00073-0,linglu@njnu.edu.cn,,Z Cai 2015,2015,2 genes,Cai-2015-The Gbeta-like protein CpcB is requir,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5961,PHI:4679,UniProt,X0JB59,GenBank,EXL98392,,,race 4 54006,FoSlt2,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),AAA group,,,root,MAP kinase,,,MAP kinase pathway,reduced virulence,,,,,,,,reduced; aberrant,,no,Congo red; calcofluor white; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25849862,PubMed,10.1371/journal.pone.0122634,PLoS One. 2015 Apr 7;10(4):e0122634,zdjiang@scau.edu.cn,FoSlt2 was required for siderophore biosynthesis under iron-depletion conditions.,Z Ding 2015,2015,3 genes,Ding-2015-Mitogen-Activated Protein Kinases Ar,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5962,PHI:4680,UniProt,X0JSI1,GenBank,EXM04167,,,race 4 54006,FoMkk2,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),AAA group,,,root,MAP kinase,,,MAP kinase pathway,reduced virulence,,,,,,,,reduced; aberrant,,no,Congo red; calcofluor white; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25849862,PubMed,10.1371/journal.pone.0122634,PLoS One. 2015 Apr 7;10(4):e0122634,zdjiang@scau.edu.cn,,Z Ding 2015,2015,3 genes,Ding-2015-Mitogen-Activated Protein Kinases Ar,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5963,PHI:4681,UniProt,X0KCM6,GenBank,EXM06457,,,race 4 54006,FoBck1,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),AAA group,,,root,MAP kinase,,,MAP kinase pathway,reduced virulence,,,,,,,,reduced; aberrant,,no,Congo red; calcofluor white; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25849862,PubMed,10.1371/journal.pone.0122634,PLoS One. 2015 Apr 7;10(4):e0122634,zdjiang@scau.edu.cn,,Z Ding 2015,2015,3 genes,Ding-2015-Mitogen-Activated Protein Kinases Ar,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5964,PHI:4682,,no data found,,,,,,PSR1,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,PINP1,UniProt: F4K2E9,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptible,,altered gene expression / gene regulation: silencing,,,RP,25902521,PubMed,10.1073/pnas.1421475112,Proc Natl Acad Sci U S A. 2015 May 5;112(18):5850-5,wenbo.ma@ucr.edu,,Y Qiao 2015,2015,1 gene,Qiao-2015-Phytophthora effector targets a nove,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5965,PHI:4683,UniProt,Q2G2U1,GenBank,ABD20913,,,USA300_FPR3757,SaeS,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sensor kinase SaeS is a member of the intramembrane-sensing histidine kinases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,25849574,PubMed,10.1371/journal.ppat.1004799,PLoS Pathog. 2015 Apr 7;11(4):e1004799,tbae@iun.edu,"The strain carrying SaeS T38A, which has elevated basal kinase activity, showed wild type level of virulence.",Q Liu 2015,2015,1 gene,Liu-2015-The Extracytoplasmic Linker Peptide o,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5966,PHI:4683,UniProt,Q2G2U1,GenBank,ABD20913,,,USA300_FPR3757,SaeS,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sensor kinase SaeS is a member of the intramembrane-sensing histidine kinases,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25849574,PubMed,10.1371/journal.ppat.1004799,PLoS Pathog. 2015 Apr 7;11(4):e1004799,tbae@iun.edu,"The strains carrying SaeS with lower basal kinase activity (i.e., SaeS W32A, G35A, and L39A) were attenuated.",Q Liu 2015,2015,1 gene,Liu-2015-The Extracytoplasmic Linker Peptide o,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5967,PHI:4683,UniProt,Q2G2U1,GenBank,ABD20913,,,USA300_FPR3757,SaeS,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sensor kinase SaeS is a member of the intramembrane-sensing histidine kinases,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25849574,PubMed,10.1371/journal.ppat.1004799,PLoS Pathog. 2015 Apr 7;11(4):e1004799,tbae@iun.edu,The strain harboring the deletion of thesaeoperon lost its virulence in infected mice.,Q Liu 2015,2015,1 gene,Liu-2015-The Extracytoplasmic Linker Peptide o,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5968,PHI:4684,UniProt,Q9HVI8,GenBank,AE004874_2,,,PAO1,MorA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,primates,9606,Homo sapiens (related: human),MRC-5 cell line,,,lung,global/motility regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25894344,PubMed,10.1371/journal.pone.0123805,PLoS One. 2015 Apr 20;10(4):e0123805,sanjay@nus.edu.sg,,A Ravichandran 2015,2015,1 gene,Ravichandran-2015-Global Regulator MorA Affect,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5969,PHI:4685,UniProt,A0A0D3QGW9,GenBank,KJ606985,,,JP718,netE,,,,,,,1502,Clostridium perfringens,,NCTC 3110,fatal canine hemorrhagic gastroenteritis; fatal foal necrotizing enterocolitis,odd-toed ungulates,9796,Equus caballus (related: horse),EO cell line,,,ovary,pore-forming toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25853427,PubMed,10.1371/journal.pone.0122684,PLoS One. 2015 Apr 8;10(4):e0122684,prescott@uoguelph.ca,,I M Gohari 2015,2015,3 genes,Gohari-2015-A Novel Pore-Forming Toxin in Type,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5970,PHI:4686,UniProt,A0A0D3QH83,GenBank,KJ606987,,,JP718,netG,,,,,,,1502,Clostridium perfringens,,NCTC 3110,fatal canine hemorrhagic gastroenteritis; fatal foal necrotizing enterocolitis,odd-toed ungulates,9796,Equus caballus (related: horse),EO cell line,,,ovary,pore-forming toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25853427,PubMed,10.1371/journal.pone.0122684,PLoS One. 2015 Apr 8;10(4):e0122684,prescott@uoguelph.ca,,I M Gohari 2015,2015,3 genes,Gohari-2015-A Novel Pore-Forming Toxin in Type,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5971,PHI:4687,UniProt,A0A0D3QGV4,GenBank,KJ606986,,,JP718,netF,,,,,,,1502,Clostridium perfringens,,NCTC 3110,fatal canine hemorrhagic gastroenteritis; fatal foal necrotizing enterocolitis,odd-toed ungulates,9796,Equus caballus (related: horse),EO cell line,,,ovary,pore-forming toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25853427,PubMed,10.1371/journal.pone.0122684,PLoS One. 2015 Apr 8;10(4):e0122684,prescott@uoguelph.ca,,I M Gohari 2015,2015,3 genes,Gohari-2015-A Novel Pore-Forming Toxin in Type,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5972,PHI:4688,UniProt,G4ML75,GenBank,EHA56811,,,70-15,MET6,,,,,,,318829,Magnaporthe oryzae,,P1.2,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sariceltik,,,leaf,methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase,,,,loss of pathogenicity,,yes,yes,yes,,,,,,no,methionine; S-methylmethionine,methionine: CHEBI:16811; S-methylmethionine: CHEBI:17728,,,,,gene deletion: full; gene complementation,,,RP,25856162,PubMed,10.1371/journal.pone.0111108,PLoS One. 2015 Apr 9;10(4):e0111108,marc-henri.lebrun@versailles.inra.fr,These pathogenicity defects were rescued by addition of exogenous methionine andS-methylmethionine.,M E Saint-Macary 2015,2015,1 gene,Saint-Macary-2015-Methionine Biosynthesis is E,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5973,PHI:4688,UniProt,G4ML75,GenBank,EHA56811,,,70-15,MET6,,,,,,,318829,Magnaporthe oryzae,,P1.2,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Express,,,leaf,methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase,,,,loss of pathogenicity,,yes,yes,yes,,,,,,no,methionine; S-methylmethionine,methionine: CHEBI:16811; S-methylmethionine: CHEBI:17728,,,,,gene deletion: full; gene complementation,,,RP,25856162,PubMed,10.1371/journal.pone.0111108,PLoS One. 2015 Apr 9;10(4):e0111108,marc-henri.lebrun@versailles.inra.fr,These pathogenicity defects were rescued by addition of exogenous methionine andS-methylmethionine.,M E Saint-Macary 2015,2015,1 gene,Saint-Macary-2015-Methionine Biosynthesis is E,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5974,PHI:4689,UniProt,Q8Y9V5,GenBank,CAC98494,,,EGD-e,pgdA,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,peptidoglycan deacetylase,,,,reduced virulence,,,,,,,,,,no,cationic antimicrobial peptide (CAMP); cefuroximel; penicillin G,cefuroximel: CHEBI:3515,,,,,gene mutation,,,RP,25157076,PubMed,10.1128/JB.02053-14,J Bacteriol. 2014 Nov;196(21):3756-67,portnoy@berkeley.edu,"The pgdA, rli31, degU, and pbpXmutants were as resistant as WT bacteria to both antibiotics and CAMP treatment,",T P Burke 2014,2014,4 genes,Burke-2014-Listeria monocytogenes is resistant,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5975,PHI:4690,UniProt,Q6DL91,GenBank,AAT74538,,,EGD,degU,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,orphan response regulator,,,,reduced virulence,,,,,,,,,,no,cationic antimicrobial peptide (CAMP); cefuroximel; penicillin G,cefuroximel: CHEBI:3515,,,,,gene mutation,,,RP,25157076,PubMed,10.1128/JB.02053-14,J Bacteriol. 2014 Nov;196(21):3756-67,portnoy@berkeley.edu,"The pgdA, rli31, degU, and pbpXmutants were as resistant as WT bacteria to both antibiotics and CAMP treatment,",T P Burke 2014,2014,4 genes,Burke-2014-Listeria monocytogenes is resistant,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5976,PHI:4691,,no data found,,,,,,rli31,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,noncoding RNA,,,,reduced virulence,,,,,,,,,,no,cationic antimicrobial peptide (CAMP); cefuroximel; penicillin G,cefuroximel: CHEBI:3515,,,,,gene mutation,,,RP,25157076,PubMed,10.1128/JB.02053-14,J Bacteriol. 2014 Nov;196(21):3756-67,portnoy@berkeley.edu,"The pgdA, rli31, degU, and pbpXmutants were as resistant as WT bacteria to both antibiotics and CAMP treatment,",T P Burke 2014,2014,4 genes,Burke-2014-Listeria monocytogenes is resistant,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5977,PHI:4692,UniProt,Q8Y9I8,GenBank,CAC98619,,,EGD-e,pbpX,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,putative carboxypeptidase,,,,reduced virulence,,,,,,,,,,no,cationic antimicrobial peptide (CAMP); cefuroximel; penicillin G,cefuroximel: CHEBI:3515,,,,,gene mutation,,,RP,25157076,PubMed,10.1128/JB.02053-14,J Bacteriol. 2014 Nov;196(21):3756-67,portnoy@berkeley.edu,"The pgdA, rli31, degU, and pbpXmutants were as resistant as WT bacteria to both antibiotics and CAMP treatment,",T P Burke 2014,2014,4 genes,Burke-2014-Listeria monocytogenes is resistant,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5978,PHI:4693,UniProt,D0ZLQ7,GenBank,AAD16960,,,14028s,mgtC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,cellulose synthesis regulation,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25848006,PubMed,10.1073/pnas.1500989112,Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5183-8,eduardo.groisman@yale.edu,,M H Pontes 2015,2015,2 genes,Pontes-2015-Salmonella promotes virulence by r,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5979,PHI:4694,UniProt,D0ZKI3,GenBank,ACY90746,,,14028s,bcsA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,cellulose synthesis regulation,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25848006,PubMed,10.1073/pnas.1500989112,Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5183-8,eduardo.groisman@yale.edu,,M H Pontes 2015,2015,2 genes,Pontes-2015-Salmonella promotes virulence by r,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5980,PHI:4693,UniProt,D0ZLQ7,GenBank,AAD16960,,,14028s,mgtC,,,,,,PHI:4694,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,cellulose synthesis regulation,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25848006,PubMed,10.1073/pnas.1500989112,Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5183-8,eduardo.groisman@yale.edu,,M H Pontes 2015,2015,2 genes,Pontes-2015-Salmonella promotes virulence by r,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5981,PHI:4694,UniProt,D0ZKI3,GenBank,ACY90746,,,14028s,bcsA,,,,,,PHI:4693,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,cellulose synthesis regulation,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25848006,PubMed,10.1073/pnas.1500989112,Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5183-8,eduardo.groisman@yale.edu,,M H Pontes 2015,2015,2 genes,Pontes-2015-Salmonella promotes virulence by r,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5982,PHI:4695,UniProt,Q2YTP4,GenBank,CAI81385,,,RF122,seg,,,,,,PHI:4696; PHI:4697,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),NMRI,,,skin,part of enterotoxin gene cluster,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25864191,PubMed,10.1007/s10096-015-2371-4,Eur J Clin Microbiol Infect Dis. 2015 Apr 12,forough.nowrouzian@microbio.gu.se,"No effect of egc was seen in a local skin and soft tissue infection model, but in an invasive infection model, increased weight loss was observed after infection with the egc+ as compared to the egc- mutant.",F L Nowrouzian 2015,2015,3 genes,Nowrouzian-2015-Impacts of enterotoxin gene cl,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5983,PHI:4696,,no data found,,,,,,selm,,,,,,PHI:4695; PHI:4697,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),NMRI,,,skin,part of enterotoxin gene cluster,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25864191,PubMed,10.1007/s10096-015-2371-4,Eur J Clin Microbiol Infect Dis. 2015 Apr 12,forough.nowrouzian@microbio.gu.se,"No effect of egc was seen in a local skin and soft tissue infection model, but in an invasive infection model, increased weight loss was observed after infection with the egc+ as compared to the egc- mutant.",F L Nowrouzian 2015,2015,3 genes,Nowrouzian-2015-Impacts of enterotoxin gene cl,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5984,PHI:4697,,no data found,,,,,,selo,,,,,,PHI:4695; PHI:4696,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),NMRI,,,skin,part of enterotoxin gene cluster,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25864191,PubMed,10.1007/s10096-015-2371-4,Eur J Clin Microbiol Infect Dis. 2015 Apr 12,forough.nowrouzian@microbio.gu.se,"No effect of egc was seen in a local skin and soft tissue infection model, but in an invasive infection model, increased weight loss was observed after infection with the egc+ as compared to the egc- mutant.",F L Nowrouzian 2015,2015,3 genes,Nowrouzian-2015-Impacts of enterotoxin gene cl,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5985,PHI:4695,UniProt,Q2YTP4,GenBank,CAI81385,,,RF122,seg,,,,,,PHI:4696; PHI:4697,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),NMRI,,,kidney,part of enterotoxin gene cluster,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25864191,PubMed,10.1007/s10096-015-2371-4,Eur J Clin Microbiol Infect Dis. 2015 Apr 12,forough.nowrouzian@microbio.gu.se,"No effect of egc was seen in a local skin and soft tissue infection model, but in an invasive infection model, increased weight loss was observed after infection with the egc+ as compared to the egc- mutant.",F L Nowrouzian 2015,2015,3 genes,Nowrouzian-2015-Impacts of enterotoxin gene cl,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5986,PHI:4696,,no data found,,,,,,selm,,,,,,PHI:4695; PHI:4697,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),NMRI,,,kidney,part of enterotoxin gene cluster,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25864191,PubMed,10.1007/s10096-015-2371-4,Eur J Clin Microbiol Infect Dis. 2015 Apr 12,forough.nowrouzian@microbio.gu.se,"No effect of egc was seen in a local skin and soft tissue infection model, but in an invasive infection model, increased weight loss was observed after infection with the egc+ as compared to the egc- mutant.",F L Nowrouzian 2015,2015,3 genes,Nowrouzian-2015-Impacts of enterotoxin gene cl,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5987,PHI:4697,,no data found,,,,,,selo,,,,,,PHI:4695; PHI:4696,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),NMRI,,,kidney,part of enterotoxin gene cluster,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25864191,PubMed,10.1007/s10096-015-2371-4,Eur J Clin Microbiol Infect Dis. 2015 Apr 12,forough.nowrouzian@microbio.gu.se,"No effect of egc was seen in a local skin and soft tissue infection model, but in an invasive infection model, increased weight loss was observed after infection with the egc+ as compared to the egc- mutant.",F L Nowrouzian 2015,2015,3 genes,Nowrouzian-2015-Impacts of enterotoxin gene cl,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5988,PHI:4698,UniProt,D0ZLQ7,GenBank,AAD16960,,,14028s,MgtC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,required for intramacrophage survival and growth in low mg2+.,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25900124,PubMed,10.1016/j.febslet.2015.04.014,FEBS Lett. 2015 May 22;589(12):1346-51,eunjinlee@khu.ac.kr,"The reduced proteolytic activity of the FtsH protease during infection further increases MgtC production, promotingSalmonella's pathogenicity inside phagocytic cells",E Choi 2015,2015,1 gene,Choi-2015-A single amino acid of a Salmonella,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5989,PHI:4699,UniProt,Q9R2W8,GenBank,AF161700_2,,,CP1250,comX1,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,alternative sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5990,PHI:4700,UniProt,B2IMI0,GenBank,ACB89265,,,CP1250,comX2,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,alternative sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5991,PHI:4699,UniProt,Q9R2W8,GenBank,AF161700_2,,,CP1250,comX1,,,,,,PHI:4700,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,alternative sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5992,PHI:4700,UniProt,B2IMI0,GenBank,ACB89265,,,CP1250,comX2,,,,,,PHI:4699,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,alternative sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5993,PHI:4701,UniProt,B2IQ18,GenBank,ACB90442,,,CGSP14,radC,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,DNA repair,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5994,PHI:4702,UniProt,P0A452,GenBank,AAL00560,,,R6,recA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,DNA recombination and repair,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5995,PHI:4703,,no data found,GenBank,ABJ54506,,,D39,spd_0981,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,cellular metabolism,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5996,PHI:4704,,no data found,GenBank,ABJ54591,,,D39,spd_0031,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,PrsW protease family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5997,PHI:4705,UniProt,B2IPD1,GenBank,ACB90205,,,CGSP14,coiA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,competence protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5998,PHI:4706,UniProt,B2IM27,GenBank,ACB91165,,,CGSP14,dinF,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,MATE efflux family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 5999,PHI:4707,UniProt,B2IMM7,GenBank,ACB91271,,,CGSP14,cglB,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,competence protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6000,PHI:4708,,no data found,GenBank,ABJ54370,,,D39,spd_0845,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,"ABC transporter, ATP-binding protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6001,PHI:4709,,no data found,GenBank,ABJ55003,,,D39,spd_1854,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6002,PHI:4710,,no data found,GenBank,ABJ54212,,,D39,spd_2026,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; lung,"ABC transporter, permease protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25846124,PubMed,10.1111/mmi.13016,Mol Microbiol. 2015 Apr 2,geelau@illinois.edu,,L Zhu 2015,2015,12 genes,Zhu-2015-Deletion analysis of Streptococcus pn,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6003,PHI:4711,UniProt,Q5K1Z4,GenBank,CAH40841,,,,mapA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,porin omp33-36,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25156738,PubMed,10.1128/IAI.02034-14,Infect Immun. 2014 Nov;82(11):4666-80,german.bou.arevalo@sergas.es,Macrophages and a mouse model of systemic infection confirm that Omp33-36 is a virulence factor in A. Baumannii.,C Rumbo 2014,2014,1 gene,Rumbo-2014-The Acinetobacter baumannii Omp33-3,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6004,PHI:4712,UniProt,P57698,GenBank,AE004591_3,,,PAO1,kdpB,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,transport of small molecules,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6005,PHI:4713,UniProt,Q9I194,GenBank,AE004664_10,,,PAO1,pvdQ,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,adaptation & protection,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6006,PHI:4714,UniProt,Q9HWR4,GenBank,AE004828_4,,,PAO1,bphO,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative enzymes,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6007,PHI:4715,UniProt,G3XDB0,GenBank,AE004946_1,,,PAO1,crc,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,energy metabolism,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6008,PHI:4716,UniProt,Q9HY13,GenBank,AE004781_9,,,PAO1,PA3613,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,unknown,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6009,PHI:4717,UniProt,Q9I167,GenBank,AE004668_12,,,PAO1,PA2414,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,L-sorbosone dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6010,PHI:4718,UniProt,Q9HUP7,GenBank,AE004904_9,,,PAO1,PA4916,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,unknown,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6011,PHI:4719,UniProt,Q9HU28,GenBank,AE004928_7,,,PAO1,PA5156,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,unknown,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6012,PHI:4712,UniProt,P57698,GenBank,AE004591_3,,,PAO1,kdpB,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,transport of small molecules,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6013,PHI:4715,UniProt,G3XDB0,GenBank,AE004946_1,,,PAO1,crc,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,energy metabolism,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6014,PHI:4716,UniProt,Q9HY13,GenBank,AE004781_9,,,PAO1,PA3613,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,unknown,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6015,PHI:4719,UniProt,Q9HU28,GenBank,AE004928_7,,,PAO1,PA5156,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,unknown,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6016,PHI:4712,UniProt,P57698,GenBank,AE004591_3,,,PAO1,kdpB,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,,transport of small molecules,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6017,PHI:4713,UniProt,Q9I194,GenBank,AE004664_10,,,PAO1,pvdQ,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,,adaptation & protection,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6018,PHI:4714,UniProt,Q9HWR4,GenBank,AE004828_4,,,PAO1,bphO,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,,putative enzymes,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6019,PHI:4715,UniProt,G3XDB0,GenBank,AE004946_1,,,PAO1,crc,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,,energy metabolism,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6020,PHI:4716,UniProt,Q9HY13,GenBank,AE004781_9,,,PAO1,PA3613,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,,unknown,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6021,PHI:4717,UniProt,Q9I167,GenBank,AE004668_12,,,PAO1,PA2414,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,,L-sorbosone dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6022,PHI:4718,UniProt,Q9HUP7,GenBank,AE004904_9,,,PAO1,PA4916,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,,unknown,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6023,PHI:4719,UniProt,Q9HU28,GenBank,AE004928_7,,,PAO1,PA5156,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,,unknown,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25845292,PubMed,10.1111/1462-2920,Environ Microbiol. 2015 Apr 3,miguel.camara@nottingham.ac.uk,The virulence of the majority of P. aeruginosamutants varied between disease models suggesting that virulence is dependent on the disease model used and hence the host environment.,J Dubern 2015,2015,8 genes,Dubern-2015-Integrated whole genome screening,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6024,PHI:4720,UniProt,A0A0A7DLN4,GenBank,AIP86908,,,98-06,Iug6,,,,,,,318829,Magnaporthe oryzae,,98-06,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25837042,PubMed,10.1371/journal.ppat.1004801,PLoS Pathog. 2015 Apr 2;11(4):e1004801,zhgzhang@njau.edu.cn,Characterization of isolate-specific effector candidates Iug6 and Iug9 and PaR candidate Iug18 revealed that they have a role in fungal propagation and pathogenicity.,Y Dong 2015,2015,3 genes,Dong-2015-Global Genome and Transcriptome Anal,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6025,PHI:4721,UniProt,A0A0A7DM22,GenBank,AIP86909,,,98-06,Iug9,,,,,,,318829,Magnaporthe oryzae,,98-06,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25837042,PubMed,10.1371/journal.ppat.1004801,PLoS Pathog. 2015 Apr 2;11(4):e1004801,zhgzhang@njau.edu.cn,Characterization of isolate-specific effector candidates Iug6 and Iug9 and PaR candidate Iug18 revealed that they have a role in fungal propagation and pathogenicity.,Y Dong 2015,2015,3 genes,Dong-2015-Global Genome and Transcriptome Anal,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6026,PHI:4722,UniProt,A0A0A7DLV6,GenBank,AIP86910,,,98-06,Iug18,,,,,,,318829,Magnaporthe oryzae,,98-06,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,pathogenicity-related (PaR) gene,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,25837042,PubMed,10.1371/journal.ppat.1004801,PLoS Pathog. 2015 Apr 2;11(4):e1004801,zhgzhang@njau.edu.cn,Characterization of isolate-specific effector candidates Iug6 and Iug9 and PaR candidate Iug18 revealed that they have a role in fungal propagation and pathogenicity.,Y Dong 2015,2015,3 genes,Dong-2015-Global Genome and Transcriptome Anal,BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6027,PHI:4723,UniProt,A0A0D2XJY4,BROAD,FOXG_04251,,,4287,gnn1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,leaf,encoding glycogenin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6028,PHI:4724,UniProt,A0A0D2XDM3,BROAD,FOXG_02003,,,4287,gls1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,leaf,glycogen synthase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6029,PHI:4725,UniProt,A0A0D2YC96,BROAD,FOXG_13927,,,4287,gbe1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,leaf,glycogen branching enzyme,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6030,PHI:4726,,no data found,BROAD,FOXG_19222,,,4287,gph1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,leaf,glycogen phosphorylase,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6031,PHI:4727,UniProt,A0A0D2XWJ8,BROAD,FOXG_08364,,,4287,gdb1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,leaf,glycogen de-branching enzyme,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6032,PHI:4726,,no data found,BROAD,FOXG_19222,,,4287,gph1,,,,,,PHI:4727,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,leaf,glycogen phosphorylase,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6033,PHI:4727,UniProt,A0A0D2XWJ8,BROAD,FOXG_08364,,,4287,gdb1,,,,,,PHI:4726,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,leaf,glycogen de-branching enzyme,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6034,PHI:4723,UniProt,A0A0D2XJY4,BROAD,FOXG_04251,,,4287,gnn1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,encoding glycogenin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6035,PHI:4724,UniProt,A0A0D2XDM3,BROAD,FOXG_02003,,,4287,gls1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glycogen synthase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6036,PHI:4725,UniProt,A0A0D2YC96,BROAD,FOXG_13927,,,4287,gbe1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glycogen branching enzyme,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6037,PHI:4726,,no data found,BROAD,FOXG_19222,,,4287,gph1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glycogen phosphorylase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6038,PHI:4727,UniProt,A0A0D2XWJ8,BROAD,FOXG_08364,,,4287,gdb1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glycogen de-branching enzyme,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6039,PHI:4726,,no data found,BROAD,FOXG_19222,,,4287,gph1,,,,,,PHI:4727,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glycogen phosphorylase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6040,PHI:4727,UniProt,A0A0D2XWJ8,BROAD,FOXG_08364,,,4287,gdb1,,,,,,PHI:4726,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glycogen de-branching enzyme,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,25865793,PubMed,10.1016/j.fgb.2015.03.014,Fungal Genet Biol. 2015 Apr;77:40-9,roncero@uco.es,"The single mutants defective in glycogen metabolism showed similar levels of virulence in the invertebrate animal model Galleria mellonella. Interestingly, the deletion of gdb1 reduced virulence on the plant host up to 40% compared to the wild type in single and in double mutant backgrounds, whereas the other mutants showed the virulence at the wild-type level.",C Corral-Ramos 2015,2015,5 genes,"Corral-Ramos-2015-Glycogen catabolism, but not",BATCH_048,2015-05-01,MC,,,,,,,,,,,,,
,,Record 6041,PHI:4735,UniProt,E6YE64,GenBank,CBI63251,,,Emoy2,ATR5,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,21361788,PubMed,10.1094/MPMI-12-10-0278,Mol Plant Microbe Interact. 2011 Jul;24(7):827-38,m.tor@worc.ac.uk,The Pseudomonas syringae pv. Tomato DC3000 delivery system was to examine the hypersensitive response (HR) elicitation.,K Bailey 2011,2011,1 gene,Bailey-2011-Molecular cloning of ATR5(Emoy2) f,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6042,PHI:4737,UniProt,F6MEZ1,GenBank,AEF57433,,,Waco9,RXLR3,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6043,PHI:4738,UniProt,F6MEZ2,GenBank,AEF57434,,,Waco9,RXLR4,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6044,PHI:4739,UniProt,F6MEZ4,GenBank,AEF57436,,,Waco9,RXLR6,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6045,PHI:4740,UniProt,F6MEZ6,GenBank,AEF57438,,,Waco9,RXLR9,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6046,PHI:4741,UniProt,F6MEZ8,GenBank,AEF57440,,,Waco9,RXLR13,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6047,PHI:4742,UniProt,F6MF00,GenBank,AEF57442,,,Waco9,RXLR16,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6048,PHI:4743,UniProt,F6MF01,GenBank,AEF57443,,,Waco9,RXLR17,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6049,PHI:4744,UniProt,F6MF03,GenBank,AEF57445,,,Waco9,RXLR19,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6050,PHI:4745,UniProt,F6MF04,GenBank,AEF57446,,,Waco9,RXLR20,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6051,PHI:4746,UniProt,F6MF05,GenBank,AEF57447,,,Waco9,RXLR21,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6052,PHI:4747,UniProt,F6MF06,GenBank,AEF57448,,,Waco9,RXLR22,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6053,PHI:4748,UniProt,F6MF07,GenBank,AEF57449,,,Waco9,RXLR23,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6054,PHI:4749,UniProt,F6MF08,GenBank,AEF57450,,,Waco9,RXLR29,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,25375163,PubMed,10.1371/journal.pone.0110624,PLoS One. 2014 Nov 6;9(11):e110624,C.M.J.Pieterse@uu.nl,,M J C Pel 2014,2014,13 genes,Pel-2014-Functional analysis of Hyaloperonospo,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6055,PHI:4751,UniProt,G3C9P1,GenBank,CCC55817,,,,HaRxL44,,transgenic Arabidopsis expressing 35S:HaRxL44,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,increased susceptibility,,functional test in host: stable expression of 35s:harxl44 in arabidopsis,,,RP; AC,24339748,PubMed,10.1371/journal.pbio.1001732,PLoS Biol. 2013 Dec;11(12):e1001732,jonathan.jones@tsl.ac.uk,Transgenic Arabidopsis expressing 35S:HaRxL44. Challenge with Hpa strain Waco9 resulted in increased disease compared to control Col-0 plants.,M Caillaud 2013,2013,1 gene,Caillaud-2013-A downy mildew effector attenuat,AC First Host Target Curation update 24_05_2016/BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6056,PHI:4751,UniProt,G3C9P1,GenBank,CCC55817,,,,HaRxL44,,none wild type HaRxL44 naturally present in Hpa strain,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,med19a-2 loss of function mutant,UniProt: Q9FMP0,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,increased susceptibility,,other evidence: host gene disruption,,,RP; AC,24339748,PubMed,10.1371/journal.pbio.1001732,PLoS Biol. 2013 Dec;11(12):e1001732,jonathan.jones@tsl.ac.uk,no data on Hpa strain used. Assume Hpa strain naturally contains HaRxL44 effector for assay on modified hosts.,M Caillaud 2013,2013,1 gene,Caillaud-2013-A downy mildew effector attenuat,AC First Host Target Curation update 24_05_2016/BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6057,PHI:4751,UniProt,G3C9P1,GenBank,CCC55817,,,,HaRxL44,,none wild type HaRxL44 naturally present in Hpa strain,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,transgenic Arabidopsis over expressing (OE) MED19a,UniProt: Q9FMP0,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,increased resistance,,functional test in host: stable overexpression of med19a in arabidopsis,,,RP; AC,24339748,PubMed,10.1371/journal.pbio.1001732,PLoS Biol. 2013 Dec;11(12):e1001732,jonathan.jones@tsl.ac.uk,no data on Hpa strain used. Assume Hpa strain naturally contains HaRxL44 effector for assay on modified hosts.,M Caillaud 2013,2013,1 gene,Caillaud-2013-A downy mildew effector attenuat,AC First Host Target Curation update 24_05_2016/BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6058,PHI:4751,UniProt,G3C9P1,GenBank,CCC55817; Ensembl: HpaG808319,,,,HaRxL44,,YFPn-HaRxL44,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: nicotiana benthamiana),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,YFPc-MED19a,UniProt: Q9FMP0; Ensembl: At5g12230,BiCF positive binding,,functional test in host: transient expression,co-expression of transgenes in Nb leaves delivered by Agrobacterium tumefaciens,,RP; AC,24339748,PubMed,10.1371/journal.pbio.1001732,PLoS Biol. 2013 Dec;11(12):e1001732,jonathan.jones@tsl.ac.uk,"MED19a is found both in the nucleoplasm and nucleolus, it disappears in the nucleoplasm in the presence of HaRxL44. HaRxL44 interacts with Mediator subunit 19a (MED19a) (Y2H data available from Mukhtar et al 2011 Science), resulting in the degradation of MED19a in a proteasome-dependent manner, shifting the balance of defence transcription from SA-responsive defence to JA/ET-signalling, and enhancing susceptibility to biotrophs by attenuating SA-dependent gene expression.",M Caillaud 2013,2013,1 gene,Caillaud-2013-A downy mildew effector attenuat,AC First Host Target Curation update 24_05_2016/BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6059,PHI:4751,UniProt,G3C9P1,GenBank,CCC55817; Ensembl: HpaG808319,,,,HaRxL44,,HA-HaRxL44,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: nicotiana benthamiana),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,GFP-MED19a,UniProt: Q9FMP0; Ensembl: At5g12230,positive co-IP with proteasome inhibitor to prevent GFP-MED19a degradation when HA-haRxL44 present,,functional test in host: transient expression,co-expression of transgenes in Nb leaves delivered by Agrobacterium tumefaciens,,RP; AC,24339748,PubMed,10.1371/journal.pbio.1001732,PLoS Biol. 2013 Dec;11(12):e1001732,jonathan.jones@tsl.ac.uk,"Futher mutant data available in paper. HaRxL44 interacts with Mediator subunit 19a (MED19a) (Y2H data available from Mukhtar et al 2011 Science), resulting in the degradation of MED19a in a proteasome-dependent manner, shifting the balance of defence transcription from SA-responsive defence to JA/ET-signalling, and enhancing susceptibility to biotrophs by attenuating SA-dependent gene expression.",M Caillaud 2013,2013,1 gene,Caillaud-2013-A downy mildew effector attenuat,AC First Host Target Curation update 24_05_2016/BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6060,PHI:4752,UniProt,B2C6F8,GenBank,ABZ10809,,,,HaRxL96,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3847,Glycine max (related: soybean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22709376,PubMed,10.1111/j.1365-313X.2012.05079.x,Plant J. 2012 Dec;72(6):882-93,johnmcd@vt.edu,HaRxL96 and PsAvh163 suppress effector-triggered programmed cell death in soybean.,R G Anderson 2012,2012,2 genes,Anderson-2012-Homologous RXLR effectors from H,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6061,PHI:4753,UniProt,B2C6F3,GenBank,ABZ10804,,,,PsAvh163,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22709376,PubMed,10.1111/j.1365-313X.2012.05079.x,Plant J. 2012 Dec;72(6):882-93,johnmcd@vt.edu,HaRxL96 and PsAvh163 suppress effector-triggered programmed cell death in soybean.,R G Anderson 2012,2012,2 genes,Anderson-2012-Homologous RXLR effectors from H,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6062,PHI:4752,UniProt,B2C6F8,GenBank,ABZ10809,,,,HaRxL96,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22709376,PubMed,10.1111/j.1365-313X.2012.05079.x,Plant J. 2012 Dec;72(6):882-93,johnmcd@vt.edu,HaRxL96 suppresses programmed cell death in N. benthamiana,R G Anderson 2012,2012,2 genes,Anderson-2012-Homologous RXLR effectors from H,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6063,PHI:4753,UniProt,B2C6F3,GenBank,ABZ10804,,,,PsAvh163,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22709376,PubMed,10.1111/j.1365-313X.2012.05079.x,Plant J. 2012 Dec;72(6):882-93,johnmcd@vt.edu,PsAvh163 triggers a hypersensitive response in N. benthamiana,R G Anderson 2012,2012,2 genes,Anderson-2012-Homologous RXLR effectors from H,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6064,PHI:4754,UniProt,Q5G7K8,GenBank,AAW63767,,,Emco5,ATR13,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6065,PHI:4755,UniProt,G3C9L0,,,,,Emoy2,HaRxL2,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6066,PHI:4756,UniProt,G3C9N6,,,,,Emoy2,HaRxL18,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6067,PHI:4757,UniProt,G3C9L1,,,,,Emoy2,HaRxL24,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6068,PHI:4758,UniProt,G3C9P0,,,,,Emoy2,HaRxL36,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6069,PHI:4759,UniProt,G3C9P1,,,,,,HaRxL44,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6070,PHI:4760,,no data found,,,,,,HaRxL45a,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6071,PHI:4761,UniProt,G3C9Q4,,,,,,HaRxL68,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6072,PHI:4762,UniProt,G3C9Q5,,,,,,HaRxL70,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6073,PHI:4763,UniProt,G3C9Q7,,,,,,HaRxL73,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6074,PHI:4764,UniProt,G3C9R3,,,,,,HaRxL89,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6075,PHI:4765,UniProt,G3C9R4,,,,,,HaRxL106,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6076,PHI:4766,UniProt,G3C9S3,,,,,,HaRxLL3a,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6077,PHI:4767,UniProt,G3C9S3,,,,,,HaRxLL60,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6078,PHI:4768,UniProt,G3C9S7,,,,,,HaRxLL108,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6079,PHI:4769,UniProt,G3C9U1,,,,,Emoy2,HaRxLL470b,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23211925,PubMed,10.1101/sqb.2012.77.015115,Cold Spring Harb Symp Quant Biol. 2012;77:285-93,jonathan.jones@tsl.ac.uk,"Nuclear localised Hpa effectors that interact directly or indirectly with host nuclear components. Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943",M C CAILLAUD 2012,2012,16 genes,Caillaud-2012-Mechanisms of nuclear suppressio,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6080,PHI:4770,UniProt,G3C9P9,GenBank,CCC55825,,,Emoy2,HaRxL62,,,,,,,272952,Hyaloperonospora arabidopsidis,,Waco9,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,RP,25329884,PubMed,10.1371/journal.ppat.1004443,PLoS Pathog. 2014 Oct 16;10(10):e1004443,jonathan.jones@tsl.ac.uk,"HaRxL62, previously shown to enhance host susceptibility, was found to suppress responsiveness to Salicylic Acid.",S Asai 2014,2014,1 gene,Asai-2014-Expression profiling during arabidop,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6081,PHI:4771,UniProt,H9BPR8,GenBank,AFD62207,,,Emoy2,ATR39-1,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Weiningen-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,22359513,PubMed,10.1371/journal.pgen.1002502,PLoS Genet. 2012;8(2):e1002502,stask@berkeley.edu,"The allelic variant of this effector, ATR39-2, is not recognized, and two amino acid residues were identified and shown to be critical for this loss of recognition.",S Goritschnig 2012,2012,1 gene,Goritschnig-2012-Computational prediction and,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6082,PHI:4772,UniProt,G3C9T8,GenBank,CCC55864,,,Emoy2,HaRxLL464,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23734779,PubMed,10.1094/MPMI-06-12-0154-R,Mol Plant Microbe Interact. 2013 Jul;26(7):745-57,jonathan.jones@sainsbury-laboratory.ac.uk,,J L Badel 2013,2013,4 genes,Badel-2013-In planta effector competition assa,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6083,PHI:4773,UniProt,G3C9T3,GenBank,CCC55859,,,Emoy2,HaRxLL441,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23734779,PubMed,10.1094/MPMI-06-12-0154-R,Mol Plant Microbe Interact. 2013 Jul;26(7):745-57,jonathan.jones@sainsbury-laboratory.ac.uk,,J L Badel 2013,2013,4 genes,Badel-2013-In planta effector competition assa,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6084,PHI:4774,UniProt,G3C9N8,GenBank,CCC55814,,,Emoy2,HaRxL22,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23734779,PubMed,10.1094/MPMI-06-12-0154-R,Mol Plant Microbe Interact. 2013 Jul;26(7):745-57,jonathan.jones@sainsbury-laboratory.ac.uk,,J L Badel 2013,2013,4 genes,Badel-2013-In planta effector competition assa,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6085,PHI:4775,UniProt,G3C9Q9,GenBank,CCC55835,,,Emoy2,HaRxL75,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23734779,PubMed,10.1094/MPMI-06-12-0154-R,Mol Plant Microbe Interact. 2013 Jul;26(7):745-57,jonathan.jones@sainsbury-laboratory.ac.uk,,J L Badel 2013,2013,4 genes,Badel-2013-In planta effector competition assa,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6086,PHI:4728,UniProt,Q5NF07,GenBank,CAG46080,,,SCHU S4,manB,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25999917,PubMed,10.3389/fmicb.2015.00338,Front Microbiol. 2015 May 5;6:338.,bradley-jones@uiowa.edu,,J A Rasmussen 2015,2015,7 genes,Rasmussen-2015-Characterization of Francisella,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6087,PHI:4729,UniProt,Q5NEZ1,GenBank,CAG46097,,,SCHU S4,wbtA,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25999917,PubMed,10.3389/fmicb.2015.00338,Front Microbiol. 2015 May 5;6:338.,bradley-jones@uiowa.edu,,J A Rasmussen 2015,2015,7 genes,Rasmussen-2015-Characterization of Francisella,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6088,PHI:4730,UniProt,Q5NGJ3,GenBank,CAG45479,,,SCHU S4,FTT0846,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25999917,PubMed,10.3389/fmicb.2015.00338,Front Microbiol. 2015 May 5;6:338.,bradley-jones@uiowa.edu,,J A Rasmussen 2015,2015,7 genes,Rasmussen-2015-Characterization of Francisella,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6089,PHI:4731,UniProt,Q5NEZ7,GenBank,CAG46091,,,SCHU S4,wzy,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25999917,PubMed,10.3389/fmicb.2015.00338,Front Microbiol. 2015 May 5;6:338.,bradley-jones@uiowa.edu,,J A Rasmussen 2015,2015,7 genes,Rasmussen-2015-Characterization of Francisella,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6090,PHI:4732,UniProt,Q5NH02,GenBank,CAG45307,,,SCHU S4,FTT0673p/prsAp,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,ribose phosphate pyrophosphokinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25999917,PubMed,10.3389/fmicb.2015.00338,Front Microbiol. 2015 May 5;6:338.,bradley-jones@uiowa.edu,,J A Rasmussen 2015,2015,7 genes,Rasmussen-2015-Characterization of Francisella,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6091,PHI:4733,UniProt,Q5NEU6,GenBank,CAG46145,,,SCHU S4,dnaJ,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25999917,PubMed,10.3389/fmicb.2015.00338,Front Microbiol. 2015 May 5;6:338.,bradley-jones@uiowa.edu,,J A Rasmussen 2015,2015,7 genes,Rasmussen-2015-Characterization of Francisella,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6092,PHI:4734,UniProt,Q5NFT3,GenBank,CAG45771,,,SCHU S4,hemH,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25999917,PubMed,10.3389/fmicb.2015.00338,Front Microbiol. 2015 May 5;6:338.,bradley-jones@uiowa.edu,,J A Rasmussen 2015,2015,7 genes,Rasmussen-2015-Characterization of Francisella,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6093,PHI:4736,UniProt,G4MYS1,GenBank,EHA55300,,,70-15,MoYpt7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,small GTPase,,,,loss of pathogenicity,,yes,,,,reduced; aberrant,,reduced; aberrant,reduced; aberrant,no,CaCl2,CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,RP,25991510,PubMed,10.1111/1462-2920.12903,Environ Microbiol. 2015 May 20,fuchenglin@zju.edu.cn,"The deltaMoYPT7 mutant showed impairment in autophagy, breached cell wall integrity, and higher sensitivity to both calcium and heavy metal stress.",X Liu 2015,2015,1 gene,Liu-2015-The small GTPase MoYpt7 is required f,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6094,PHI:4750,UniProt,A0A0D5BX39,GenBank,AJW67919,,,,ChPMA2,,,,,,,80884,Colletotrichum higginsianum,,Chku80,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,plasma membrane proton pump,,,,loss of pathogenicity,,no,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,25992547,PubMed,10.1371/journal.pone.0125960,PLoS One. 2015 May 19;10(5):e0125960,christian.koch@fau.de,,M Korn 2015,2015,1 gene,Korn-2015-A Genetic Screen for Pathogenicity G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6095,PHI:4776,UniProt,Q0TX07,GenBank,EAT76667,,,SN15,SnPKS19,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),,,,leaf,polyketide synthase for alternariol mycotoxin biosynthesis,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26025896,PubMed,10.1128/AEM.00278-15,Appl Environ Microbiol. 2015 May 29. pii: AEM.00278-15,yitheng.chooi@uwa.edu,deltaSnPKS19 mutants showed that SnPKS19 and AOH are not involved in virulence and oxidative stress tolerance.,Y Chooi 2015,2015,1 gene,Chooi-2015-SnPKS19 encodes the polyketide synt,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6096,PHI:4777,,no data found,,,,,,Csfus3,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch; common root rot,monocots,4513,Hordeum vulgare (related: barley),cv. Bowman,,,leaf,mitogen-activated protein kinases,,,MAP kinase pathway,loss of pathogenicity,,yes,,,,aberrant; reduced,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26011429,PubMed,10.1371/journal.pone.0128291,PLoS One. 2015 May 26;10(5):e0128291,shaobin.zhong@ndsu.edu,,Y Leng 2015,2015,4 genes,Leng-2015-The Role of Mitogen-Activated Protei,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6097,PHI:4778,UniProt,M2TIY7,GenBank,EMD69171,,,ND90Pr,Csste11,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch; common root rot,monocots,4513,Hordeum vulgare (related: barley),cv. Bowman,,,leaf,MAPK kinase kinase,,,MAP kinase pathway,loss of pathogenicity,,yes,,,,aberrant; reduced,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26011429,PubMed,10.1371/journal.pone.0128291,PLoS One. 2015 May 26;10(5):e0128291,shaobin.zhong@ndsu.edu,,Y Leng 2015,2015,4 genes,Leng-2015-The Role of Mitogen-Activated Protei,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6098,PHI:4779,UniProt,M2SJ60,GenBank,EMD62405,,,ND90Pr,Cshog1,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch; common root rot,monocots,4513,Hordeum vulgare (related: barley),cv. Bowman,,,leaf,mitogen-activated protein kinases,,,MAP kinase pathway,reduced virulence,,no,,,,wild type,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26011429,PubMed,10.1371/journal.pone.0128291,PLoS One. 2015 May 26;10(5):e0128291,shaobin.zhong@ndsu.edu,,Y Leng 2015,2015,4 genes,Leng-2015-The Role of Mitogen-Activated Protei,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6099,PHI:4780,,no data found,,,,,,Csslt2,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch; common root rot,monocots,4513,Hordeum vulgare (related: barley),cv. Bowman,,,leaf,mitogen-activated protein kinases,,,MAP kinase pathway,reduced virulence,,no,,,,reduced,,increased; aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26011429,PubMed,10.1371/journal.pone.0128291,PLoS One. 2015 May 26;10(5):e0128291,shaobin.zhong@ndsu.edu,,Y Leng 2015,2015,4 genes,Leng-2015-The Role of Mitogen-Activated Protei,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6100,PHI:4777,,no data found,,,,,,Csfus3,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch; common root rot,monocots,4513,Hordeum vulgare (related: barley),cv. Bowman,,,root,mitogen-activated protein kinases,,,MAP kinase pathway,unaffected pathogenicity,,yes,,,,aberrant; reduced,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26011429,PubMed,10.1371/journal.pone.0128291,PLoS One. 2015 May 26;10(5):e0128291,shaobin.zhong@ndsu.edu,,Y Leng 2015,2015,4 genes,Leng-2015-The Role of Mitogen-Activated Protei,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6101,PHI:4778,UniProt,M2TIY7,GenBank,EMD69171,,,ND90Pr,Csste11,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch; common root rot,monocots,4513,Hordeum vulgare (related: barley),cv. Bowman,,,root,MAPK kinase kinase,,,MAP kinase pathway,loss of pathogenicity,,yes,,,,aberrant; reduced,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26011429,PubMed,10.1371/journal.pone.0128291,PLoS One. 2015 May 26;10(5):e0128291,shaobin.zhong@ndsu.edu,,Y Leng 2015,2015,4 genes,Leng-2015-The Role of Mitogen-Activated Protei,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6102,PHI:4779,UniProt,M2SJ60,GenBank,EMD62405,,,ND90Pr,Cshog1,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch; common root rot,monocots,4513,Hordeum vulgare (related: barley),cv. Bowman,,,root,mitogen-activated protein kinases,,,MAP kinase pathway,unaffected pathogenicity,,no,,,,wild type,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26011429,PubMed,10.1371/journal.pone.0128291,PLoS One. 2015 May 26;10(5):e0128291,shaobin.zhong@ndsu.edu,,Y Leng 2015,2015,4 genes,Leng-2015-The Role of Mitogen-Activated Protei,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6103,PHI:4780,,no data found,,,,,,Csslt2,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,spot blotch; common root rot,monocots,4513,Hordeum vulgare (related: barley),cv. Bowman,,,root,mitogen-activated protein kinases,,,MAP kinase pathway,reduced virulence,,no,,,,reduced,,increased; aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26011429,PubMed,10.1371/journal.pone.0128291,PLoS One. 2015 May 26;10(5):e0128291,shaobin.zhong@ndsu.edu,,Y Leng 2015,2015,4 genes,Leng-2015-The Role of Mitogen-Activated Protei,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6104,PHI:4781,UniProt,C6C4B2,GenBank,ACS85486,,,Ech703,SlyA,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,"regulates a wide variety of biological processes in bacteria, including metabolic pathways, stress responses, virulence and degradation of harmful chemicals.",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,26027774,PubMed,10.1016/j.resmic.2015.05.004,Res Microbiol. 2015 May 28. pii: S0923-2508(15)00079-0,ahhirat@ipc.shizuoka.ac.jp,"In low (10mM) magnesium medium that activates the PhoP-PhoQ system, growth and virulence of the DslyA mutant were much lower than for the wild type.",M M Haque 2015,2015,1 gene,"Haque-2015-SlyA regulates motA and motB, virul",BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6105,PHI:4782,UniProt,A0A098KL11,GenBank,CEH37895,,,LE3-1,HrpG,,,,,,,346,Xanthomonas citri,611301,subsp. citri strain Xcc99-1330,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,the hrp cluster encodes the type III protein secretion system and is regulated by the transcription factors HrpG and HrpX.,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25961560,PubMed,10.1371/journal.pone.0125516,PLoS One. 2015 May 11;10(5):e0125516,ottado@ibr-conicet.gov.ar,The arginine 210 residue is crucial for the transcriptional activity of HrpG revealed by the absence of disease in host plants and hypersensitive response in non-host plants.,F A Ficarra 2015,2015,1 gene,Ficarra-2015-The Amino Acid Arginine 210 of th,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6106,PHI:4783,UniProt,J4VW09,GenBank,EJP62625,,,ARSEF 2860,Fkh2,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,forkhead transcription factor,,,,reduced virulence,,,,,,increased,,reduced,reduced,no,menadione; H2O2; carbendazim; dimetachlone; sorbitol; NaCl; Congo red; SDS,"menadione: CHEBI:28869; H2O2: CHEBI:16240; carbendazim: CHEBI:3392, CAS:10605-21-7; dimetachlone: CAS:24096-53-5; sorbitol: CHEBI:17924; NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984",,,,,gene disruption; gene complementation,,,RP,25955538,PubMed,10.1038/srep10108,Sci Rep. 2015 May 8;5:10108,mgfeng@zju.edu.cn,deltaFkh2displayed attenuated virulence and decreased tolerance to chemical and environmental stresses.,J Wang 2015,2015,1 gene,Wang-2015-Transcriptional control of fungal ce,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6107,PHI:4785,UniProt,J9VJ99,GenBank,AFR93481,,,H99,PFA4,chromosome 2,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,"encodes a protein S-acyl transferase (PAT), one of a family of DHHC domain-containing proteins that catalyzes lipid modification of proteins.",,,,loss of pathogenicity,,,,,,,,aberrant,,no,SDS; H2O2; KCl; NaCl; CFW; CR; LY,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; lucifer yellow: CHEBI:52104,,,,,gene mutation,,,RP,25970403,PubMed,10.1371/journal.ppat.1004908,PLoS Pathog. 2015 May 13;11(5):e1004908,doering@wustl.edu,"pfa4deltawas sensitive to plasma membrane damaging agents (SDS and H2O2), osmotic stress (KCl and NaCl), cell wall binding dyes (CFW, CR, and LY), and elevated temperature (37°C). Only temperature sensitivity could be rescued by sorbitol.",F H Santiago-Tirado 2015,2015,1 gene,Santiago-Tirado-2015-A Single Protein S-acyl T,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6108,PHI:4786,,no data found,,,,,,AS87_03285,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,phosphoribosylaminoimidazole carboxylase (NCAIR synthetase),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6109,PHI:4787,,no data found,,,,,,AS87_10600,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,phosphoadenosine phosphosulfate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6110,PHI:4788,,no data found,,,,,,AS87_06385,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,"transcriptional regulator, LuxR family",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6111,PHI:4789,,no data found,,,,,,AS87_08785,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,gliding motility protein Gldk,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6112,PHI:4790,,no data found,,,,,,AS87_04980,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,antitermination protein NusB,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6113,PHI:4791,,no data found,,,,,,AS87_01735,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,PncA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6114,PHI:4792,,no data found,,,,,,AS87_04750,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,inosine-5-monophosphate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6115,PHI:4793,,no data found,,,,,,AS87_06670,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6116,PHI:4794,,no data found,,,,,,AS87_01090,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6117,PHI:4795,,no data found,,,,,,AS87_10710,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6118,PHI:4796,,no data found,,,,,,AS87_00910,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,phosphoribosylaminoimidazole (AIR)synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6119,PHI:4797,,no data found,,,,,,AS87_00505,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,gliding motility protein GldG,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6120,PHI:4798,,no data found,,,,,,AS87_01210,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,phosphoribosylformylglycinamidine (FGAM) synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6121,PHI:4799,,no data found,,,,,,AS87_09335,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6122,PHI:4800,,no data found,,,,,,AS87_09295,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,pyruvate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6123,PHI:4801,,no data found,,,,,,AS87_04850,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6124,PHI:4802,,no data found,,,,,,AS87_10665,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6125,PHI:4803,,no data found,,,,,,AS87_04765,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,"beta-carotene 15,15'-monooxygenase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6126,PHI:4804,,no data found,,,,,,AS87_06745,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6127,PHI:4805,,no data found,,,,,,AS87_01220,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,amidophosphoribosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6128,PHI:4806,,no data found,,,,,,AS87_05545,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,biotin synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6129,PHI:4807,,no data found,,,,,,AS87_09530,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,8-amino-7-oxononanoate synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6130,PHI:4808,,no data found,,,,,,AS87_08840,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,Holliday junction resolvase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6131,PHI:4809,,no data found,,,,,,AS87_02660,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,DNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6132,PHI:4810,,no data found,,,,,,AS87_09440,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,ATPases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6133,PHI:4811,,no data found,,,,,,AS87_09345,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6134,PHI:4812,,no data found,,,,,,AS87_08115,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,gliding motility protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6135,PHI:4813,,no data found,,,,,,AS87_10760,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,amino acid transporters,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6136,PHI:4814,,no data found,,,,,,AS87_05585,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6137,PHI:4815,,no data found,,,,,,AS87_08795,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,gliding motility protein GldM,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6138,PHI:4816,,no data found,,,,,,AS87_04755,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6139,PHI:4817,,no data found,,,,,,AS87_07960,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,dihydroorotase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6140,PHI:4818,,no data found,,,,,,AS87_01015,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,glycosyl transferase family 2,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6141,PHI:4819,UniProt,A0A097IB07,GenBank,AIT59279,,,Yb2,AS87_04050,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,Vi polysaccharide biosynthesis protein VipB/TviC,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6142,PHI:4820,,no data found,,,,,,AS87_00250,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,PorT protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6143,PHI:4821,,no data found,,,,,,AS87_07135,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6144,PHI:4822,,no data found,,,,,,AS87_09985,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6145,PHI:4823,,no data found,,,,,,AS87_04845,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6146,PHI:4824,,no data found,,,,,,AS87_10150,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,phosphoesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6147,PHI:4825,,no data found,,,,,,AS87_05075,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,ATPase AAA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6148,PHI:4826,,no data found,,,,,,AS87_09245,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,restriction endonuclease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6149,PHI:4827,,no data found,,,,,,AS87_09000,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,ankyrin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6150,PHI:4828,,no data found,,,,,,AS87_07625,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,fructose-bisphosphate aldolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6151,PHI:4829,,no data found,,,,,,AS87_10020,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6152,PHI:4830,,no data found,,,,,,AS87_05990,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6153,PHI:4831,,no data found,,,,,,AS87_08340,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,TonB-dependent receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6154,PHI:4832,,no data found,,,,,,AS87_05195,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6155,PHI:4833,,no data found,,,,,,AS87_00480,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002892,PubMed,10.1128/AEM.00828-15,Appl Environ Microbiol. 2015 May 22. pii: AEM.00828-15,yus@shvri.ac.cn,,X Wang 2015,2015,48 genes,Wang-2015-Whole-genome Sequence Analysis and G,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6156,PHI:4834,UniProt,Q8YBU4,GenBank,AAL54034,,,16M,TceSR,chromosome 2,,,,,,29459,Brucella melitensis,224914,16M,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,two-component regulatory system,,,,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene mutation,,,RP,25721466,PubMed,10.1111/lam.12408,Lett Appl Microbiol. 2015 Jun;60(6):565-71,chuangfu_chen@163.com,"Compared to 16M, the survival of 16MDTceSR under tress environments including that low pH (pH 2 5), high salt (NaCl) and high temperature (50°C)conditions was reduced.",Z Li 2015,2015,1 gene,Li-2015-TceSR two-component regulatory system,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6157,PHI:4835,UniProt,B9WGE7,GenBank,CAX42321,,,CD36,Csr1/ZAP1,chromosome 4,,,,,,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,birds,9031,Gallus gallus (related: chicken),,,,egg,maintains zinc homeostasis,,,,reduced virulence,,,,,,,,wild type,wild type,no,,,,,,,gene mutation; gene complementation,,,RP,26002718,PubMed,10.1128/EC.00078-15,Eukaryot Cell. 2015 May 22. pii: EC.00078-15,sascha.brunke@leibniz-hki.de,,B Böttcher 2015,2015,1 gene,Bottcher-2015-Csr1_Zap1 maintains zinc homeost,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6158,PHI:4836,UniProt,W0H5E5,GenBank,AHF67763,,,JBC1,Cif B,,,,,,,36746,Pseudomonas cichorii,,SF1-54,bacterial midrib rot (lettuce),eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Butter head,,,leaf,linear lipopeptides of the syringafactin family and are involved in virulence and surface motility,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25961750,PubMed,10.1094/MPMI-03-15-0061-R,Mol Plant Microbe Interact. 2015 May 11,monica.hofte@ugent.be,"The cichopeptin-deficient mutant of P. cichorii SF1-54 exhibited significantly weaker virulence to butterhead lettuce than the parental strain, but SF1-54-deltacipA was as virulent as the cichofactin-deficient mutant, indicating that both phytotoxic cichopeptins and motility-related cichofactins affect virulence of P. cichorii SF1-54 on lettuce.",C Huang 2015,2015,2 genes,"Huang-2015-Characterization of Cichopeptins, N",BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6159,PHI:4837,UniProt,A0A024CHY4,GenBank,AHZ34238,,,SF1-54,cipA,,,,,,,36746,Pseudomonas cichorii,,SF1-54,bacterial midrib rot (lettuce),eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Butter head,,,leaf,phytotoxic cyclic lipodepsipeptides,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25961750,PubMed,10.1094/MPMI-03-15-0061-R,Mol Plant Microbe Interact. 2015 May 11,monica.hofte@ugent.be,"The cichopeptin-deficient mutant of P. cichorii SF1-54 exhibited significantly weaker virulence to butterhead lettuce than the parental strain, but SF1-54-deltacipA was as virulent as the cichofactin-deficient mutant, indicating that both phytotoxic cichopeptins and motility-related cichofactins affect virulence of P. cichorii SF1-54 on lettuce.",C Huang 2015,2015,2 genes,"Huang-2015-Characterization of Cichopeptins, N",BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6160,PHI:4838,,no data found,,,,,,PcCRN4,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,reduced infections,altered gene expression / gene regulation: silencing,,,RP,26011314,PubMed,10.1371/journal.pone.0127965,PLoS One. 2015 May 26;10(5):e0127965,ddou@njau.edu.cn,,J J Mafurah 2015,2015,1 gene,Mafurah-2015-A Virulence Essential CRN Effecto,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6161,PHI:4838,,no data found,,,,,,PcCRN4,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,reduced infections,altered gene expression / gene regulation: silencing,,,RP,26011314,PubMed,10.1371/journal.pone.0127965,PLoS One. 2015 May 26;10(5):e0127965,ddou@njau.edu.cn,,J J Mafurah 2015,2015,1 gene,Mafurah-2015-A Virulence Essential CRN Effecto,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6162,PHI:4838,,no data found,,,,,,PcCRN4,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,increased infection,altered gene expression / gene regulation: overexpression,,,RP,26011314,PubMed,10.1371/journal.pone.0127965,PLoS One. 2015 May 26;10(5):e0127965,ddou@njau.edu.cn,,J J Mafurah 2015,2015,1 gene,Mafurah-2015-A Virulence Essential CRN Effecto,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6163,PHI:4838,,no data found,,,,,,PcCRN4,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,increased infection,altered gene expression / gene regulation: overexpression,,,RP,26011314,PubMed,10.1371/journal.pone.0127965,PLoS One. 2015 May 26;10(5):e0127965,ddou@njau.edu.cn,,J J Mafurah 2015,2015,1 gene,Mafurah-2015-A Virulence Essential CRN Effecto,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6164,PHI:4838,,no data found,,,,,,PcCRN4,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,cell death,functional test in host: transient expression,,,RP,26011314,PubMed,10.1371/journal.pone.0127965,PLoS One. 2015 May 26;10(5):e0127965,ddou@njau.edu.cn,,J J Mafurah 2015,2015,1 gene,Mafurah-2015-A Virulence Essential CRN Effecto,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6165,PHI:4838,,no data found,,,,,,PcCRN4,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,cell death,functional test in host: transient expression,,,RP,26011314,PubMed,10.1371/journal.pone.0127965,PLoS One. 2015 May 26;10(5):e0127965,ddou@njau.edu.cn,,J J Mafurah 2015,2015,1 gene,Mafurah-2015-A Virulence Essential CRN Effecto,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6166,PHI:4839,,no data found,JGI,Ps506062,,,,PsHint1,,,,PsGPA1,UniProt: B2ZFL2; GenBank: ACD03826,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Hefeng 47,,,seedling,A HIT domain-containing protein required for chemotaxis and pathogenicity,,,,reduced virulence,,no,no,yes,,,,,aberrant,no,,,,,,cell death,altered gene expression / gene regulation: silencing,,,RP,25976113,PubMed,10.1111/mpp.12279,Mol Plant Pathol. 2015 May 14,wangyc@njau.edu.cn,"During interaction with a susceptible soybean cultivar, PsHint1-silenced transformants displayed significantlyreducedinfectious hyphal extension and caused a strong cell death in plants. Etiolated seedlings were assayed.",X Zhang 2015,2015,1 gene,"Zhang-2015-PsHint1, associated with the G-prot",BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6167,PHI:4840,UniProt,G7TGB4,GenBank,AEQ97861,,,BLS256,hshA,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,leaf,DSF-controlled virulence-associated genes,,,DSF signalling,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26020828,PubMed,10.1094/PHYTO-07-14-0190-R,Phytopathology. 2015 May;105(5):588-96,glqian@njau.edu.cn,,Z Song 2015,2015,2 genes,Song-2015-Identification and Characterization,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6168,PHI:4841,UniProt,G7TGB3,GenBank,AEQ97860,,,BLS256,hshC,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,leaf,DSF-controlled virulence-associated genes,,,DSF signalling,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26020828,PubMed,10.1094/PHYTO-07-14-0190-R,Phytopathology. 2015 May;105(5):588-96,glqian@njau.edu.cn,,Z Song 2015,2015,2 genes,Song-2015-Identification and Characterization,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6169,PHI:4842,UniProt,I1BW02,GenBank,EIE80382,,,RA 99-880,Fob1,,,,,,,64495,Rhizopus arrhizus,,99-880,mucormycosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,brain; kidney,iron uptake from ferrioxamine,,,reductase/high affinity iron permease pathway,reduced virulence,,,,,,,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25974051,PubMed,10.1371/journal.ppat.1004842,PLoS Pathog. 2015 May 14;11(5):e1004842,ibrahim@labiomed.org,"A R. oryzaestrain with targeted reduced Fob1/Fob2 expression was impaired for iron uptake, germinating, and growing on medium with ferrioxamine as the sole source of iron. This strain also exhibited reduced virulence in a deferoxamine-treated, but not the diabetic ketoacidotic (DKA), mouse model of mucormycosis.",M Liu 2015,2015,3 genes,Liu-2015-Fob1 and Fob2 Proteins Are Virulence,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6170,PHI:4843,UniProt,I1CCV9,GenBank,EIE86289,,,RA 99-880,Fob2,,,,,,,64495,Rhizopus arrhizus,,99-880,mucormycosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,brain; kidney,iron uptake from ferrioxamine,,,reductase/high affinity iron permease pathway,reduced virulence,,,,,,,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25974051,PubMed,10.1371/journal.ppat.1004842,PLoS Pathog. 2015 May 14;11(5):e1004842,ibrahim@labiomed.org,"A R. oryzaestrain with targeted reduced Fob1/Fob2 expression was impaired for iron uptake, germinating, and growing on medium with ferrioxamine as the sole source of iron. This strain also exhibited reduced virulence in a deferoxamine-treated, but not the diabetic ketoacidotic (DKA), mouse model of mucormycosis.",M Liu 2015,2015,3 genes,Liu-2015-Fob1 and Fob2 Proteins Are Virulence,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6171,PHI:4844,UniProt,I1BRD6,GenBank,EIE78766,,,RA 99-880,FTR1,,,,,,,64495,Rhizopus arrhizus,,99-880,mucormycosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,brain; kidney,high affinity iron permease,,,reductase/high affinity iron permease pathway,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25974051,PubMed,10.1371/journal.ppat.1004842,PLoS Pathog. 2015 May 14;11(5):e1004842,ibrahim@labiomed.org,"A R. oryzaestrain with targeted reduced Fob1/Fob2 expression was impaired for iron uptake, germinating, and growing on medium with ferrioxamine as the sole source of iron. This strain also exhibited reduced virulence in a deferoxamine-treated, but not the diabetic ketoacidotic (DKA), mouse model of mucormycosis.",M Liu 2015,2015,3 genes,Liu-2015-Fob1 and Fob2 Proteins Are Virulence,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6172,PHI:4845,UniProt,A0A0E3USI9,GenBank,AKC92820,,,ATCC 96836,PL1332,,,,,,,29001,Alternaria brassicicola,622360,EGS 42-002,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,pectate lyase-coding gene,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25996954,PubMed,10.1371/journal.pone.0127140,PLoS One. 2015 May 21;10(5):e0127140,bykim@kribb.re.kr,,Y Cho 2015,2015,1 gene,Cho-2015-A Pectate Lyase-Coding Gene Abundantl,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6173,PHI:4846,UniProt,B3VA60,GenBank,ACE75886,,,H292,covR,,,,,,,1314,Streptococcus pyogenes,,SF370,infection,primates,9606,Homo sapiens (related: human),,,,blood,,,,,reduced virulence,,,,,,,,reduced,,no,3Furancarboxaldehyde (3FCA),3Furancarboxaldehyde (3FCA) CAS: CAS:498-60-2,,,,,altered gene expression / gene regulation: downregulation,,,RP,25978065,PubMed,10.1371/journal.pone.0127210,PLoS One. 2015 May 15;10(5):e0127210,sk_pandian@rediffmail.com,,G A Subramenium 2015,2015,1 gene,Ashwinkumar Sub-2015-covR Mediated Antibiofilm,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6174,PHI:4847,UniProt,G3C9N5,GenBank,CCC55811,,,Emoy2,HaRxL17,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,21914011,PubMed,10.1111/j.1365-313X.2011.04787.x,Plant J. 2012 Jan;69(2):252-65,jonathan.jones@tsl.ac.uk,,M Caillaud 2012,2012,1 gene,Caillaud-2012-Subcellular localization of the,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6175,PHI:4848,UniProt,Q2A0P1,GenBank,ACY39283,,,BFOL-51,Avr2,,,,Six5,UniProt: C0LT61,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. C32,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,resistance,gene deletion: full; gene complementation,,,RP,25967461,PubMed,10.1111/nph.13455,New Phytol. 2015 May 13,f.l.w.takken@uva.nl,,L Ma 2015,2015,2 genes,Ma-2015-The AVR2-SIX5 gene pair is required to,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6176,PHI:4849,UniProt,C0LT61,GenBank,ACN87967,,,,Six5,,,,Avr2,UniProt: Q2A0P1,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. C32,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,resistance,gene deletion: full; gene complementation,,,RP,25967461,PubMed,10.1111/nph.13455,New Phytol. 2015 May 13,f.l.w.takken@uva.nl,,L Ma 2015,2015,2 genes,Ma-2015-The AVR2-SIX5 gene pair is required to,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6177,PHI:4850,,no data found,GenBank,KJ716229,,,,FocVel1,,,,,,,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain FocGD,Fusarium wilt (cucumber),eudicots,3659,Cucumis sativus (related: cucumber),cv. 9930,,,leaf,diverse cellular processes,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,KCl; sorbitol; iprodione; prochloraz; hymexazol; Congo red; caffeine,"KCl: CHEBI:32588; sorbitol: CHEBI:17924; iprodione: CHEBI:28909, CAS:36734-19-7; prochloraz: CHEBI:8434; hymexazol: CHEBI:5827; Congo red: CHEBI:34653; caffeine: CHEBI:27732",,,,,gene deletion: full; gene complementation,,,RP,25999976,PubMed,10.3389/fpls.2015.00312,Front Plant Sci. 2015 May 6;6:312,linbr@126.com,,Peiqian Li,2015,1 gene,Li-2015-FocVel1 influences asexual production,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6178,PHI:4851,UniProt,G3C9P6,GenBank,CCC55822,,,Emoy2,HaRxL57,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6179,PHI:4852,UniProt,G3C9N5,GenBank,CCC55811,,,Emoy2,HaRxL17,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6180,PHI:4853,UniProt,G3C9Q5,GenBank,CCC55831,,,Emoy2,HaRxL70,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6181,PHI:4854,UniProt,G3C9T3,GenBank,CCC55859,,,Emoy2,HaRxLL441,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6182,PHI:4855,UniProt,G3C9S3,GenBank,CCC55849,,,Emoy2,HaRxLL60,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6183,PHI:4856,UniProt,G3C9P9,GenBank,CCC55825,,,Emoy2,HaRxL62,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6184,PHI:4857,UniProt,G3C9R4,GenBank,CCC55840,,,Emoy2,HaRxL106,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6185,PHI:4851,UniProt,G3C9P6,GenBank,CCC55822,,,Emoy2,HaRxL57,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6186,PHI:4852,UniProt,G3C9N5,GenBank,CCC55811,,,Emoy2,HaRxL17,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6187,PHI:4853,UniProt,G3C9Q5,GenBank,CCC55831,,,Emoy2,HaRxL70,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6188,PHI:4854,UniProt,G3C9T3,GenBank,CCC55859,,,Emoy2,HaRxLL441,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6189,PHI:4855,UniProt,G3C9S3,GenBank,CCC55849,,,Emoy2,HaRxLL60,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6190,PHI:4856,UniProt,G3C9P9,GenBank,CCC55825,,,Emoy2,HaRxL62,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6191,PHI:4857,UniProt,G3C9R4,GenBank,CCC55840,,,Emoy2,HaRxL106,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6192,PHI:4851,UniProt,G3C9P6,GenBank,CCC55822,,,Emoy2,HaRxL57,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6193,PHI:4852,UniProt,G3C9N5,GenBank,CCC55811,,,Emoy2,HaRxL17,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6194,PHI:4853,UniProt,G3C9Q5,GenBank,CCC55831,,,Emoy2,HaRxL70,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6195,PHI:4854,UniProt,G3C9T3,GenBank,CCC55859,,,Emoy2,HaRxLL441,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6196,PHI:4855,UniProt,G3C9S3,GenBank,CCC55849,,,Emoy2,HaRxLL60,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6197,PHI:4856,UniProt,G3C9P9,GenBank,CCC55825,,,Emoy2,HaRxL62,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6198,PHI:4857,UniProt,G3C9R4,GenBank,CCC55840,,,Emoy2,HaRxL106,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22072967,PubMed,10.1371/journal.ppat.1002348,PLoS Pathog. 2011 Nov;7(11):e1002348,jonathan.jones@sainsbury-laboratory.ac.uk,,Fabro et al,2011,7 genes,Fabro-2011-Multiple candidate effectors from t,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6199,PHI:4858,,no data found,,BP106B_I2046,,,,BpaB,,,,,,,13373,Burkholderia mallei,243160,ATCC 23344,glanders,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,autotransporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25993100,PubMed,10.1371/journal.pone.0126437,PLoS One. 2015 May 20;10(5):e0126437,elafon10@uga.edu,,S M Zimmerman 2015,2015,1 gene,Zimmerman-2015-The Autotransporter BpaB Contri,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6200,PHI:4859,UniProt,P13039,GenBank,AAA23757,,,,Fes,,,,,,,562,Escherichia coli,475609,serotype O78:K80:H9 strain χ7122,respiratory disease (poultry); systemic disease (poultry),birds,9031,Gallus gallus (related: chicken),,,,,catecholate siderophore esterases,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25982934,PubMed,10.1111/mmi.13059,Mol Microbiol. 2015 May 18,charles.dozois@iaf.inrs.ca,,M Caza 2015,2015,3 genes,Caza-2015-Catecholate siderophore esterases Fe,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6201,PHI:4860,UniProt,Q8G8P0,GenBank,AAN76096AF449499_2,,,EB1,IroD,,,,,,,562,Escherichia coli,475609,serotype O78:K80:H9 strain χ7122,respiratory disease (poultry); systemic disease (poultry),birds,9031,Gallus gallus (related: chicken),,,,,catecholate siderophore esterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25982934,PubMed,10.1111/mmi.13059,Mol Microbiol. 2015 May 18,charles.dozois@iaf.inrs.ca,,M Caza 2015,2015,3 genes,Caza-2015-Catecholate siderophore esterases Fe,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6202,PHI:4861,UniProt,Q7WTI6,GenBank,AAP42473,,,,IroE,,,,,,,562,Escherichia coli,475609,serotype O78:K80:H9 strain χ7122,respiratory disease (poultry); systemic disease (poultry),birds,9031,Gallus gallus (related: chicken),,,,,catecholate siderophore esterases,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25982934,PubMed,10.1111/mmi.13059,Mol Microbiol. 2015 May 18,charles.dozois@iaf.inrs.ca,,M Caza 2015,2015,3 genes,Caza-2015-Catecholate siderophore esterases Fe,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6203,PHI:4859,UniProt,P13039,GenBank,AAA23757,,,,Fes,,,,,,PHI:4860,562,Escherichia coli,475609,serotype O78:K80:H9 strain χ7122,respiratory disease (poultry); systemic disease (poultry),birds,9031,Gallus gallus (related: chicken),,,,,catecholate siderophore esterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25982934,PubMed,10.1111/mmi.13059,Mol Microbiol. 2015 May 18,charles.dozois@iaf.inrs.ca,,M Caza 2015,2015,3 genes,Caza-2015-Catecholate siderophore esterases Fe,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6204,PHI:4860,UniProt,Q8G8P0,GenBank,AAN76096AF449499_2,,,EB1,IroD,,,,,,PHI:4859,562,Escherichia coli,475609,serotype O78:K80:H9 strain χ7122,respiratory disease (poultry); systemic disease (poultry),birds,9031,Gallus gallus (related: chicken),,,,,catecholate siderophore esterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25982934,PubMed,10.1111/mmi.13059,Mol Microbiol. 2015 May 18,charles.dozois@iaf.inrs.ca,,M Caza 2015,2015,3 genes,Caza-2015-Catecholate siderophore esterases Fe,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6205,PHI:4859,UniProt,P13039,GenBank,AAA23757,,,,Fes,,,,,,PHI:4860; PHI:4861,562,Escherichia coli,475609,serotype O78:K80:H9 strain χ7122,respiratory disease (poultry); systemic disease (poultry),birds,9031,Gallus gallus (related: chicken),,,,,catecholate siderophore esterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25982934,PubMed,10.1111/mmi.13059,Mol Microbiol. 2015 May 18,charles.dozois@iaf.inrs.ca,,M Caza 2015,2015,3 genes,Caza-2015-Catecholate siderophore esterases Fe,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6206,PHI:4860,UniProt,Q8G8P0,GenBank,AAN76096AF449499_2,,,EB1,IroD,,,,,,PHI:4859; PHI:4861,562,Escherichia coli,475609,serotype O78:K80:H9 strain χ7122,respiratory disease (poultry); systemic disease (poultry),birds,9031,Gallus gallus (related: chicken),,,,,catecholate siderophore esterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25982934,PubMed,10.1111/mmi.13059,Mol Microbiol. 2015 May 18,charles.dozois@iaf.inrs.ca,,M Caza 2015,2015,3 genes,Caza-2015-Catecholate siderophore esterases Fe,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6207,PHI:4861,UniProt,Q7WTI6,GenBank,AAP42473,,,,IroE,,,,,,PHI:4859; PHI:4860,562,Escherichia coli,475609,serotype O78:K80:H9 strain χ7122,respiratory disease (poultry); systemic disease (poultry),birds,9031,Gallus gallus (related: chicken),,,,,catecholate siderophore esterases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25982934,PubMed,10.1111/mmi.13059,Mol Microbiol. 2015 May 18,charles.dozois@iaf.inrs.ca,,M Caza 2015,2015,3 genes,Caza-2015-Catecholate siderophore esterases Fe,BATCH_049,2015-06-01,MC,,,,,,,,,,,,,
,,Record 6208,PHI:2435,,no data found,JGI,Myc fi1:87167,,,,MfAvr4,,,,,,,1873960,Pseudocercospora fijiensis,383855,CIRAD86,black sigatoka,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,20368413,PubMed,10.1073/pnas.1002910107,,pierre.dewit@wur.nl,Potato Virus X (PVX)-based expression system and Agrobacterium tumefaciens,Ioannis Stergiopoulos,2010,,Stergiopoulos-2010-Tomato Cf resistance,Batch011,2011-01-01,MC,,,,,,,,,,,,,
,,Record 6209,PHI:2435,,no data found,JGI,Myc fi1:87167,,,,MfAvr4,,,,,,,1873960,Pseudocercospora fijiensis,383855,CIRAD86,black sigatoka,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,20368413,PubMed,10.1073/pnas.1002910107,,pierre.dewit@wur.nl,Potato Virus X (PVX)-based expression system and Agrobacterium tumefaciens,Ioannis Stergiopoulos,2010,,,Batch011,2011-01-01,MC,,,,,,,,,,,,,
,,Record 6210,PHI:2436,,no data found,JGI,Myc fi1:60658,,,,MFEcp2,,,,,,,1873960,Pseudocercospora fijiensis,383855,CIRAD86,black sigatoka,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,20368413,PubMed,10.1073/pnas.1002910107,,pierre.dewit@wur.nl,Potato Virus X (PVX)-based expression system and Agrobacterium tumefaciens,Ioannis Stergiopoulos,2010,,,Batch011,2011-01-01,MC,,,,,,,,,,,,,
,,Record 6211,PHI:2442,UniProt,F9XQ56,Ensembl Genomes,Mycgr3g88451,,,IPO323,MgNLP,chromosome 13,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,leaf blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,cell death and defense signalling,,,,unaffected pathogenicity,,,,,,wild type,,,,no,,,,,,,gene deletion: full,,,RP,19522561,PubMed,10.1094/MPMI-22-7-0790,,jason.rudd@bbsrc.ac.uk,no comments,Juliet Motteram,2009,,MPMI-22-7-0790,Batch012,2011-01-01,MC,,,,,,,,,,,,,
,,Record 6212,PHI:2460,UniProt,W7MNW1,FTFD,FVEG_08855.3,,,,FLBA1,,,,,,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,regulators of G-protein signalling,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,21535353,PubMed,10.1111/J.1364-3703.2010.00686.X,,wbshim@tamu.edu,no comments,Mala Mukherje,2011,,Mukherjee-2011-Regulators of G-prot,Batch013,2011-01-01,MC,,,,,,,,,,,,,
,,Record 6213,PHI:2461,UniProt,W7MCR6,FTFD,FVEG_06192.3,,,,FLBA2,,,,,,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,regulators of G-protein signalling,,,,unaffected pathogenicity,,,,,,reduced,wild type,reduced,wild type; aberrant,no,,,,,,,gene deletion: full,,,RP,21535353,PubMed,10.1111/J.1364-3703.2010.00686.X,,wbshim@tamu.edu,no comments,Mala Mukherje,2011,,Mukherjee-2011-Regulators of G-prot,Batch013,2011-01-01,MC,,,,,,,,,,,,,
,,Record 6214,PHI:2462,UniProt,W7MHG4,FTFD,FVEG_09572.3,,,,RGSB,,,,,,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,regulators of G-protein signalling,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced,wild type,no,,,,,,,gene deletion: full,,,RP,21535353,PubMed,10.1111/J.1364-3703.2010.00686.X,,wbshim@tamu.edu,no comments,Mala Mukherje,2011,,Mukherjee-2011-Regulators of G-prot,Batch013,2011-01-01,MC,,,,,,,,,,,,,
,,Record 6215,PHI:2463,UniProt,W7LT88,FTFD,FVEG_03826.3,,,,RGSC1,,,,,,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,regulators of G-protein signalling,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,wild type,no,,,,,,,gene deletion: full,,,RP,21535353,PubMed,10.1111/J.1364-3703.2010.00686.X,,wbshim@tamu.edu,no comments,Mala Mukherje,2011,,Mukherjee-2011-Regulators of G-prot,Batch013,2011-01-01,MC,,,,,,,,,,,,,
,,Record 6216,PHI:4862,,no data found,,,,,,GrvRS,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,kidney; bladder,two-component regulatory system; main regulator ofaceexpression under these stress conditions.,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,25385790,PubMed,10.1128/IAI.02587-14,Infect Immun. 2015 Jan;83(1):389-95,Jung.H.Roh@uth.tmc.edu,A grvR mutant revealed decreased collagen binding and biofilm formation as well as attenuation in a murine urinary tract infection model.,J H Roh 2014,2014,1 gene,Roh-2014-The Two-component System GrvRS (aka E,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6217,PHI:4863,UniProt,Q4TUK0,GenBank,AAY56866,,,ATCC 700905,murM,,,,,,PHI:4864,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),,,,lung,penicillin resistance causes decreased Ply release with concomitant increases in the amount of branched stem peptides.,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26114646,PubMed,10.1371/journal.ppat.1004996,PLoS Pathog. 2015 Jun 26;11(6):e1004996,andrew.camilli@tufts.edu,"murMN deletion mutant, increased Ply release is detrimental to virulence during a murine model of pneumonia.",N G Greene 2015,2015,2 genes,Greene-2015-Peptidoglycan Branched Stem Peptid,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6218,PHI:4864,UniProt,Q9L446,GenBank,AAY56876,,,ATCC 700905,murN,,,,,,PHI:4863,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),,,,lung,penicillin resistance causes decreased Ply release with concomitant increases in the amount of branched stem peptides.,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26114646,PubMed,10.1371/journal.ppat.1004996,PLoS Pathog. 2015 Jun 26;11(6):e1004996,andrew.camilli@tufts.edu,"murMN deletion mutant, increased Ply release is detrimental to virulence during a murine model of pneumonia.",N G Greene 2015,2015,2 genes,Greene-2015-Peptidoglycan Branched Stem Peptid,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6219,PHI:4865,UniProt,A0A098DWK6,EMBL,FGRAMPH1_01T22767,,,PH-1,FgVam7,chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spike,regulatory role in cellular differentiation and virulence,,,,loss of pathogenicity,yes,,,,,reduced,reduced,reduced,reduced,no,NaCl; sorbitol; H2O2; calcofluor white; sodium dodecylsulfate (SDS); Congo red,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984; NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924,,,,,gene deletion: full; gene complementation,,,RP,25880818,PubMed,10.1111/mpp.12267,Mol Plant Pathol. 2015 Apr 16,zhgzhang@njau.edu.cn,,H Zhang 2015,2015,1 gene,Zhang-2015-SNARE protein FgVam7 controls growt,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6220,PHI:4865,UniProt,A0A098DWK6,EMBL,FGRAMPH1_01T22767,,,PH-1,FgVam7,chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,regulatory role in cellular differentiation and virulence,,,,loss of pathogenicity,yes,,,,,reduced,reduced,reduced,reduced,no,NaCl; sorbitol; H2O2; calcofluor white; sodium dodecylsulfate (SDS); Congo red,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984; NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924,,,,,gene deletion: full; gene complementation,,,RP,25880818,PubMed,10.1111/mpp.12267,Mol Plant Pathol. 2015 Apr 16,zhgzhang@njau.edu.cn,,H Zhang 2015,2015,1 gene,Zhang-2015-SNARE protein FgVam7 controls growt,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6221,PHI:4866,UniProt,K0E4Z9,GenBank,WP_015083909,,,FSC200,FTS_0201,,,,,,,263,Francisella tularensis,351581,FSC200,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; lung,tetratricopeptide repeat-like proteins,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene mutation,,,RP,25245806,PubMed,10.1128/IAI.01620-14,Infect Immun. 2014 Dec;82(12):5035-48,cervenyl@faf.cuni.cz,,V Dankova 2014,2014,3 genes,Dankova-2014-Characterization of TPR-like prot,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6222,PHI:4867,UniProt,K0EAA2,GenBank,AFT92640,,,FSC200,FTS_0778,,,,,,,263,Francisella tularensis,351581,FSC200,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; lung,tetratricopeptide repeat-like proteins,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene mutation,,,RP,25245806,PubMed,10.1128/IAI.01620-14,Infect Immun. 2014 Dec;82(12):5035-48,cervenyl@faf.cuni.cz,,V Dankova 2014,2014,3 genes,Dankova-2014-Characterization of TPR-like prot,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6223,PHI:4868,UniProt,K0E596,GenBank,AFT93312,,,FSC200,FTS_1680,,,,,,,263,Francisella tularensis,351581,FSC200,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; lung,tetratricopeptide repeat-like proteins,,,,reduced virulence,,,,,,,,,,,,,,,,,gene mutation; gene complementation,,,RP,25245806,PubMed,10.1128/IAI.01620-14,Infect Immun. 2014 Dec;82(12):5035-48,cervenyl@faf.cuni.cz,,V Dankova 2014,2014,3 genes,Dankova-2014-Characterization of TPR-like prot,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6224,PHI:4869,UniProt,Q3BQU4,GenBank,CAJ24869,,,85-10,XopAP,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial spot (pepper); bacterial spot (tomato),eudicots,4072,Capsicum annuum (no common name found),,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26104875,PubMed,10.1111/mpp.12288,Mol Plant Pathol. 2015 Jun 23,talp@tau.ac.il; guidos@post.tau.ac.il,Inactivation of the xopAPgene reduced the severity of disease symptoms in infected plants.,D Teper 2015,2015,7 genes,Teper-2015-Identification of novel Xanthomonas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6225,PHI:4870,UniProt,Q3BWD6,GenBank,CAJ22827,,,85-10,XopAU,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial spot (pepper); bacterial spot (tomato),eudicots,4072,Capsicum annuum (no common name found),,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26104875,PubMed,10.1111/mpp.12288,Mol Plant Pathol. 2015 Jun 23,talp@tau.ac.il; guidos@post.tau.ac.il,Inactivation of the xopAPgene reduced the severity of disease symptoms in infected plants.,D Teper 2015,2015,7 genes,Teper-2015-Identification of novel Xanthomonas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6226,PHI:4871,UniProt,Q3BWD5,GenBank,CAJ22828,,,85-10,XopAV,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial spot (pepper); bacterial spot (tomato),eudicots,4072,Capsicum annuum (no common name found),,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26104875,PubMed,10.1111/mpp.12288,Mol Plant Pathol. 2015 Jun 23,talp@tau.ac.il; guidos@post.tau.ac.il,Inactivation of the xopAPgene reduced the severity of disease symptoms in infected plants.,D Teper 2015,2015,7 genes,Teper-2015-Identification of novel Xanthomonas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6227,PHI:4872,UniProt,Q3BQY9,GenBank,CAJ24824,,,85-10,XopAW,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial spot (pepper); bacterial spot (tomato),eudicots,4072,Capsicum annuum (no common name found),,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26104875,PubMed,10.1111/mpp.12288,Mol Plant Pathol. 2015 Jun 23,talp@tau.ac.il; guidos@post.tau.ac.il,Inactivation of the xopAPgene reduced the severity of disease symptoms in infected plants.,D Teper 2015,2015,7 genes,Teper-2015-Identification of novel Xanthomonas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6228,PHI:4873,UniProt,Q3C018,GenBank,CAJ19898,,,85-10,XopAX,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial spot (pepper); bacterial spot (tomato),eudicots,4072,Capsicum annuum (no common name found),,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26104875,PubMed,10.1111/mpp.12288,Mol Plant Pathol. 2015 Jun 23,talp@tau.ac.il; guidos@post.tau.ac.il,Inactivation of the xopAPgene reduced the severity of disease symptoms in infected plants.,D Teper 2015,2015,7 genes,Teper-2015-Identification of novel Xanthomonas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6229,PHI:4874,UniProt,Q3BNZ6,GenBank,CAJ25517,,,85-10,XopAK,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial spot (pepper); bacterial spot (tomato),eudicots,4072,Capsicum annuum (no common name found),,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26104875,PubMed,10.1111/mpp.12288,Mol Plant Pathol. 2015 Jun 23,talp@tau.ac.il; guidos@post.tau.ac.il,Inactivation of the xopAPgene reduced the severity of disease symptoms in infected plants.,D Teper 2015,2015,7 genes,Teper-2015-Identification of novel Xanthomonas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6230,PHI:4875,UniProt,Q3BMG7,GenBank,CAJ26046,,,85-10,XopAD,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial spot (pepper); bacterial spot (tomato),eudicots,4072,Capsicum annuum (no common name found),,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26104875,PubMed,10.1111/mpp.12288,Mol Plant Pathol. 2015 Jun 23,talp@tau.ac.il; guidos@post.tau.ac.il,Inactivation of the xopAPgene reduced the severity of disease symptoms in infected plants.,D Teper 2015,2015,7 genes,Teper-2015-Identification of novel Xanthomonas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6231,PHI:4876,UniProt,P0A9E5,GenBank,AAA87981,,,K-12,FNR,,,,,,,562,Escherichia coli,199310,CFT073,infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney,global regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25245807,PubMed,10.1128/IAI.02315-14,Infect Immun. 2014 Dec;82(12):5086-98,liganwu@iastate.edu,,N L Barbieri 2014,2014,1 gene,Barbieri-2014-FNR Regulates the Expression of,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6232,PHI:4877,UniProt,A0A0C6FEF7,GenBank,BAQ43449,,,NCGM257,znuA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,"plays a central role in the process of zinc uptake in zinc poor environments, including the tissues of the infected host.",,,,reduced virulence,,,,,,,,reduced,,no,calprotectin,,,,,,gene deletion: full; gene complementation,,,RP,25751674,PubMed,10.1039/c5mt00017c,Metallomics. 2015 Jun 10;7(6):1023-35,andrea.battistoni@uniroma2.it,"The znuA mutant strain is more sensitive than the wild type strain to calprotectin-mediated growth inhibition, but both the strains are highly resistant to this zinc sequestering antimicrobial protein.",M D'Orazio 2015,2015,1 gene,D'Orazio-2015-The capability of Pseudomonas ae,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6233,PHI:4878,UniProt,Q5A6B6,GenBank,EAK98205,,,SC5314,Ppg1,chromosome 4,,,,,,5476,Candida albicans,,DK318,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,A putative serine/threonine protein phosphatase type 2A.,,,cAMP-PKA filamentous growth signaling pathway,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation,,,RP,25326520,PubMed,10.1128/EC.00199-14,Eukaryot Cell. 2014 Dec;13(12):1538-47,kadosh@uthscsa.edu,"PPG1, encoding a putative type 2A-related protein phosphatase, is important forC. albicansfilament extension, invasion, and virulence in a mouse model of systemic candidiasis.",M T Albataineh 2015,2014,1 gene,"Albataineh-2014-Ppg1, a PP2A-type Protein Phos",BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6234,PHI:4879,UniProt,A0A0C4DHY2,,,,,4287,pg1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,root,endopolygalacturonase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26060046,PubMed,10.1111/mpp.12283,Mol Plant Pathol. 2015 Jun 9,roncero@uco.es,"While the single deletion mutants did not display a significant virulence reduction on tomato plants, the deltapg1deltapgx6 double mutant was significantly attenuated in virulence.",G B Ruiz 2015,2015,2 genes,Bravo Ruiz-2015-Combined action of the major s,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6235,PHI:4880,UniProt,A0A0C4DHY4,,,,,4287,pgx6,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,root,exopolygalacturonase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26060046,PubMed,10.1111/mpp.12283,Mol Plant Pathol. 2015 Jun 9,roncero@uco.es,"While the single deletion mutants did not display a significant virulence reduction on tomato plants, the deltapg1deltapgx6 double mutant was significantly attenuated in virulence.",G B Ruiz 2015,2015,2 genes,Bravo Ruiz-2015-Combined action of the major s,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6236,PHI:4879,UniProt,A0A0C4DHY2,,,,,4287,pg1,,,,,,PHI:4880,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,root,endopolygalacturonase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26060046,PubMed,10.1111/mpp.12283,Mol Plant Pathol. 2015 Jun 9,roncero@uco.es,"While the single deletion mutants did not display a significant virulence reduction on tomato plants, the deltapg1deltapgx6 double mutant was significantly attenuated in virulence.",G B Ruiz 2015,2015,2 genes,Bravo Ruiz-2015-Combined action of the major s,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6237,PHI:4880,UniProt,A0A0C4DHY4,,,,,4287,pgx6,,,,,,PHI:4879,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,root,exopolygalacturonase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26060046,PubMed,10.1111/mpp.12283,Mol Plant Pathol. 2015 Jun 9,roncero@uco.es,"While the single deletion mutants did not display a significant virulence reduction on tomato plants, the deltapg1deltapgx6 double mutant was significantly attenuated in virulence.",G B Ruiz 2015,2015,2 genes,Bravo Ruiz-2015-Combined action of the major s,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6238,PHI:4881,UniProt,B5E5S1,GenBank,ACF55224,,,G54,HPr,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,,,,Lethal pathogen phenotype,,,,HPr(ser) kinase/phosphatase,,,,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,25898857,PubMed,10.1111/mmi.13033,Mol Microbiol. 2015 Apr 21,andrew.camilli@tufts.edu,Carbon catabolite repression by seryl phosphorylated HPr is essential to Streptococcus pneumoniae.,E Fleming 2015,2015,1 gene,Fleming-2015-Carbon catabolite repression by s,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6239,PHI:4882,UniProt,H2H549,GenBank,AEX71806,,,CDCE 8392,CDCE8392_0813,,,,,,,1717,Corynebacterium diphtheriae,698965,CDC-E8392,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,tellurite-resistance protein,,,,reduced virulence,,,,,,,,,,no,TeO3; H2O2,TeO3: CHEBI:30477; H2O2: CHEBI:16240,,,,,gene disruption,,,RP,26107188,PubMed,10.1590/0074-02760140479,Mem Inst Oswaldo Cruz. 2015 Jun 24. pii: S0074-02762015005040479,guaraldi@uerj.br,"The disruption of CDCE8392_0813 gene expression in the LDCIC-L1 mutant increased susceptibility to TeO32-and reactive oxygen species (hydrogen peroxide), but not to other antimicrobial agents. The LDCIC-L1 mutant also showed a decrease in both the lethality of Caenorhabditis elegans and the survival inside of human epithelial cells compared to wild-type strain.",L S dos Santos 2015,2015,1 gene,Santos-2015-Corynebacterium diphtheriae putati,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6240,PHI:4883,UniProt,J9VMG2,GenBank,AFR93794,,,H99,Kcs1,chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,IP6kinase,,,,reduced virulence,yes,,,,,,,reduced; aberrant,,no,posaconazole; voriconazole; itraconazole; fluconazole; flucytosine; amphotericin B; SDS; caffeine,"posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; fluconazole: CHEBI:46081, CAS:86386-73-4; flucytosine: CHEBI:5100; amphotericin B: CHEBI:2682; SDS: CHEBI:8984; caffeine: CHEBI:27732",,,,,gene mutation,,,RP,26037119,PubMed,10.1128/mBio.00531-15,MBio. 2015 Jun 2;6(3):e00531-15,julianne.djordjevic@sydney.edu.au,The kcs1 mutant is hypersusceptible to antifungal agents.,S Lev 2015,2015,1 gene,Lev-2015-Fungal Inositol Pyrophosphate IP7 Is,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6241,PHI:4883,UniProt,J9VMG2,GenBank,AFR93794,,,H99,Kcs1,chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung,IP6kinase,,,,loss of pathogenicity,yes,,,,,,,reduced; aberrant,,no,posaconazole; voriconazole; itraconazole; fluconazole; flucytosine; amphotericin B; SDS; caffeine,"posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; fluconazole: CHEBI:46081, CAS:86386-73-4; flucytosine: CHEBI:5100; amphotericin B: CHEBI:2682; SDS: CHEBI:8984; caffeine: CHEBI:27732",,,,,gene mutation,,,RP,26037119,PubMed,10.1128/mBio.00531-15,MBio. 2015 Jun 2;6(3):e00531-15,julianne.djordjevic@sydney.edu.au,The kcs1 mutant is hypersusceptible to antifungal agents.,S Lev 2015,2015,1 gene,Lev-2015-Fungal Inositol Pyrophosphate IP7 Is,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6242,PHI:4884,,no data found,GenBank,KP100338,,,DI21,pPHDP70,,,,,,,38293,Photobacterium damselae,1200302,subsp. piscicida strain DI21,pasteurellosis,bony fishes,52904,Scophthalmus maximus (related: turbot),,,,,transmissible plasmid-borne pathogenicity island encodes piscibactin biosynthesis.,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion,,,RP,26092457,PubMed,10.1128/AEM.01580-15,Appl Environ Microbiol. 2015 Jun 19. pii: AEM.01580-15,cr.osorio@usc.es,"P. Damselae subsp. piscicidastrains cured of pPHDP70 no longer produced piscibactin, had impaired growth under iron limited conditions,and exhibited markedly decreased virulence in fish.",C R Osorio 2015,2015,1 gene,Osorio-2015-A transmissible plasmid-borne path,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6243,PHI:4885,UniProt,G4MTK9,GenBank,EHA55568,,,70-15,MoYpd1p,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mediator of osmotic stress and in the mode of action of the phenylpyrrole fludioxonil.,,,high osmolarity glycerol (HOG) signalling,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,,no,fludioxonil; NaCl; KCl; sorbitol; CoCl2; NaNO2,fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:17924; CoCl2: CHEBI:35696; NaNO2: CHEBI:78870,,,,,gene deletion: full; gene complementation,,,RP,26058534,PubMed,10.1016/j.funbio.2015.03.003,Fungal Biol. 2015 Jul;119(7):580-94,thines@ibwf.de,MoYpd1p is required for adaption to high osmolarity via the HOG pathway inMagnaporthe oryzae,S Jacob 2015,2015,1 gene,Jacob-2015-High osmolarity glycerol (HOG) sign,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6244,PHI:4886,UniProt,A0A094Y528,GenBank,AIX62431,,,ECONIH1,RyhB,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney; spleen,small regulatory noncoding RNA,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25245805,PubMed,10.1128/IAI.02287-14,Infect Immun. 2014 Dec;82(12):5056-68,charles.dozois@iaf.inrs.ca,"The fur mutant was more sensitive to oxidative stress and produced more of the siderophores enterobactin, salmochelins, and aerobactin than the wild-type strain. In contrast, while RyhB was not implicated in oxidative stress resistance, the ryhBmutant produced lower levels of siderophores.",G Porcheron 2014,2014,2 genes,Porcheron-2014-The small RNA RyhB contributes,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6245,PHI:4887,UniProt,P0A9A9,GenBank,CAA26429,,,K12,Fur,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney; spleen,global ferric uptake regulator,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,25245805,PubMed,10.1128/IAI.02287-14,Infect Immun. 2014 Dec;82(12):5056-68,charles.dozois@iaf.inrs.ca,"The fur mutant was more sensitive to oxidative stress and produced more of the siderophores enterobactin, salmochelins, and aerobactin than the wild-type strain. In contrast, while RyhB was not implicated in oxidative stress resistance, the ryhBmutant produced lower levels of siderophores.",G Porcheron 2014,2014,2 genes,Porcheron-2014-The small RNA RyhB contributes,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6246,PHI:4886,UniProt,A0A094Y528,GenBank,AIX62431,,,ECONIH1,RyhB,,,,,,PHI:4887,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney; spleen,small regulatory noncoding RNA,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25245805,PubMed,10.1128/IAI.02287-14,Infect Immun. 2014 Dec;82(12):5056-68,charles.dozois@iaf.inrs.ca,"The fur mutant was more sensitive to oxidative stress and produced more of the siderophores enterobactin, salmochelins, and aerobactin than the wild-type strain. In contrast, while RyhB was not implicated in oxidative stress resistance, the ryhBmutant produced lower levels of siderophores.",G Porcheron 2014,2014,2 genes,Porcheron-2014-The small RNA RyhB contributes,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6247,PHI:4887,UniProt,P0A9A9,GenBank,CAA26429,,,K12,Fur,,,,,,PHI:4886,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney; spleen,global ferric uptake regulator,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25245805,PubMed,10.1128/IAI.02287-14,Infect Immun. 2014 Dec;82(12):5056-68,charles.dozois@iaf.inrs.ca,"The fur mutant was more sensitive to oxidative stress and produced more of the siderophores enterobactin, salmochelins, and aerobactin than the wild-type strain. In contrast, while RyhB was not implicated in oxidative stress resistance, the ryhBmutant produced lower levels of siderophores.",G Porcheron 2014,2014,2 genes,Porcheron-2014-The small RNA RyhB contributes,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6248,PHI:4888,UniProt,Q59KV2,GenBank,EAK91104,,,SC5314,pst3,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue,involved in cell wall integrity,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; menadione; KCl; sorbitol; Congo red; calcofluor white,H2O2: CHEBI:16240; menadione: CHEBI:28869; sorbitol: CHEBI:30911; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; KCl: CHEBI:32588,,,,,gene mutation,,,RP,26087349,PubMed,10.1016/j.jprot.2015.06.006,J Proteomics. 2015 Jun 15. pii: S1874-3919(15)30043-9,luciamon@ucm.es,"Pst3, Tos1, Orf19.3060 and Orf19.5352 are involved in cell wall integrity and in C. albicans' engulfment by macrophages.",A Gil-Bona 2015,2015,4 genes,Gil-Bona-2015-Candida albicans cell shaving un,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6249,PHI:4889,UniProt,Q5AJA4,GenBank,EAL02851,,,SC5314,tos1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue,involved in cell wall integrity,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; menadione; KCl; sorbitol; Congo red; calcofluor white,H2O2: CHEBI:16240; menadione: CHEBI:28869; sorbitol: CHEBI:30911; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; KCl: CHEBI:32588,,,,,gene mutation,,,RP,26087349,PubMed,10.1016/j.jprot.2015.06.006,J Proteomics. 2015 Jun 15. pii: S1874-3919(15)30043-9,luciamon@ucm.es,"Pst3, Tos1, Orf19.3060 and Orf19.5352 are involved in cell wall integrity and in C. albicans' engulfment by macrophages.",A Gil-Bona 2015,2015,4 genes,Gil-Bona-2015-Candida albicans cell shaving un,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6250,PHI:4890,UniProt,Q5AHZ2,GenBank,EAL02480,,,SC5314,orf19.3060,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue,involved in cell wall integrity,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; menadione; KCl; sorbitol; Congo red; calcofluor white,H2O2: CHEBI:16240; menadione: CHEBI:28869; sorbitol: CHEBI:30911; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; KCl: CHEBI:32588,,,,,gene mutation,,,RP,26087349,PubMed,10.1016/j.jprot.2015.06.006,J Proteomics. 2015 Jun 15. pii: S1874-3919(15)30043-9,luciamon@ucm.es,"Pst3, Tos1, Orf19.3060 and Orf19.5352 are involved in cell wall integrity and in C. albicans' engulfment by macrophages.",A Gil-Bona 2015,2015,4 genes,Gil-Bona-2015-Candida albicans cell shaving un,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6251,PHI:4891,UniProt,Q5A5P7,GenBank,EAK98099,,,SC5314,orf19.5352,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue,involved in cell wall integrity,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; menadione; KCl; sorbitol; Congo red; calcofluor white,H2O2: CHEBI:16240; menadione: CHEBI:28869; sorbitol: CHEBI:30911; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; KCl: CHEBI:32588,,,,,gene mutation,,,RP,26087349,PubMed,10.1016/j.jprot.2015.06.006,J Proteomics. 2015 Jun 15. pii: S1874-3919(15)30043-9,luciamon@ucm.es,"Pst3, Tos1, Orf19.3060 and Orf19.5352 are involved in cell wall integrity and in C. albicans' engulfment by macrophages.",A Gil-Bona 2015,2015,4 genes,Gil-Bona-2015-Candida albicans cell shaving un,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6252,PHI:4892,UniProt,Q4WUI1,GenBank,EAL91745,,,Af293,aspA,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,septin,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,caspofungin; nikkomycin Z; micafungin,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,RP,26051489,PubMed,10.1016/j.fgb.2015.05.014,Fungal Genet Biol. 2015 Jun 5;81:41-51,bill.steinbach@duke.edu,"All the septins are dispensable in normal growth conditions, AspA, AspB, AspC and AspE are required for regular septation. Furthermore, deletion of only the core septin genes significantly reduced conidiation.",J M Vargas-Muñiz 2015,2015,5 genes,Vargas-Muniz-2015-The Aspergillus fumigatus se,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6253,PHI:4893,UniProt,Q4WGK7,GenBank,EAL86934,,,Af293,aspB,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,septin,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,caspofungin; nikkomycin Z; micafungin,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,RP,26051489,PubMed,10.1016/j.fgb.2015.05.014,Fungal Genet Biol. 2015 Jun 5;81:41-51,bill.steinbach@duke.edu,"All the septins are dispensable in normal growth conditions, AspA, AspB, AspC and AspE are required for regular septation. Furthermore, deletion of only the core septin genes significantly reduced conidiation.",J M Vargas-Muñiz 2015,2015,5 genes,Vargas-Muniz-2015-The Aspergillus fumigatus se,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6254,PHI:4894,UniProt,Q4WEI0,GenBank,EAL85997,,,Af293,aspC,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,septin,,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,caspofungin; nikkomycin Z; micafungin,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,RP,26051489,PubMed,10.1016/j.fgb.2015.05.014,Fungal Genet Biol. 2015 Jun 5;81:41-51,bill.steinbach@duke.edu,"All the septins are dispensable in normal growth conditions, AspA, AspB, AspC and AspE are required for regular septation. Furthermore, deletion of only the core septin genes significantly reduced conidiation.",J M Vargas-Muñiz 2015,2015,5 genes,Vargas-Muniz-2015-The Aspergillus fumigatus se,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6255,PHI:4895,UniProt,Q4WTL8,GenBank,EAL90214,,,Af293,aspD,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,septin,,,,unaffected pathogenicity,,,,,,reduced,,wild type,,no,caspofungin; nikkomycin Z; micafungin,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,RP,26051489,PubMed,10.1016/j.fgb.2015.05.014,Fungal Genet Biol. 2015 Jun 5;81:41-51,bill.steinbach@duke.edu,"All the septins are dispensable in normal growth conditions, AspA, AspB, AspC and AspE are required for regular septation. Furthermore, deletion of only the core septin genes significantly reduced conidiation.",J M Vargas-Muñiz 2015,2015,5 genes,Vargas-Muniz-2015-The Aspergillus fumigatus se,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6256,PHI:4896,UniProt,Q4WWT7,GenBank,EAL92866,,,Af293,aspE,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,septin,,,,unaffected pathogenicity,,,,,,wild type,,aberrant,,no,caspofungin; nikkomycin Z; micafungin,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,RP,26051489,PubMed,10.1016/j.fgb.2015.05.014,Fungal Genet Biol. 2015 Jun 5;81:41-51,bill.steinbach@duke.edu,"All the septins are dispensable in normal growth conditions, AspA, AspB, AspC and AspE are required for regular septation. Furthermore, deletion of only the core septin genes significantly reduced conidiation.",J M Vargas-Muñiz 2015,2015,5 genes,Vargas-Muniz-2015-The Aspergillus fumigatus se,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6257,PHI:4892,UniProt,Q4WUI1,GenBank,EAL91745,,,Af293,aspA,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,septin,,,,increased virulence (hypervirulence),,,,,,reduced,,aberrant,,no,caspofungin; nikkomycin Z; micafungin,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,RP,26051489,PubMed,10.1016/j.fgb.2015.05.014,Fungal Genet Biol. 2015 Jun 5;81:41-51,bill.steinbach@duke.edu,"All the septins are dispensable in normal growth conditions, AspA, AspB, AspC and AspE are required for regular septation. Furthermore, deletion of only the core septin genes significantly reduced conidiation.",J M Vargas-Muñiz 2015,2015,5 genes,Vargas-Muniz-2015-The Aspergillus fumigatus se,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6258,PHI:4893,UniProt,Q4WGK7,GenBank,EAL86934,,,Af293,aspB,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,septin,,,,increased virulence (hypervirulence),,,,,,reduced,,aberrant,,no,caspofungin; nikkomycin Z; micafungin,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,RP,26051489,PubMed,10.1016/j.fgb.2015.05.014,Fungal Genet Biol. 2015 Jun 5;81:41-51,bill.steinbach@duke.edu,"All the septins are dispensable in normal growth conditions, AspA, AspB, AspC and AspE are required for regular septation. Furthermore, deletion of only the core septin genes significantly reduced conidiation.",J M Vargas-Muñiz 2015,2015,5 genes,Vargas-Muniz-2015-The Aspergillus fumigatus se,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6259,PHI:4894,UniProt,Q4WEI0,GenBank,EAL85997,,,Af293,aspC,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,septin,,,,increased virulence (hypervirulence),,,,,,reduced,,aberrant,,no,caspofungin; nikkomycin Z; micafungin,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,RP,26051489,PubMed,10.1016/j.fgb.2015.05.014,Fungal Genet Biol. 2015 Jun 5;81:41-51,bill.steinbach@duke.edu,"All the septins are dispensable in normal growth conditions, AspA, AspB, AspC and AspE are required for regular septation. Furthermore, deletion of only the core septin genes significantly reduced conidiation.",J M Vargas-Muñiz 2015,2015,5 genes,Vargas-Muniz-2015-The Aspergillus fumigatus se,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6260,PHI:4895,UniProt,Q4WTL8,GenBank,EAL90214,,,Af293,aspD,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,septin,,,,unaffected pathogenicity,,,,,,reduced,,wild type,,no,caspofungin; nikkomycin Z; micafungin,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,RP,26051489,PubMed,10.1016/j.fgb.2015.05.014,Fungal Genet Biol. 2015 Jun 5;81:41-51,bill.steinbach@duke.edu,"All the septins are dispensable in normal growth conditions, AspA, AspB, AspC and AspE are required for regular septation. Furthermore, deletion of only the core septin genes significantly reduced conidiation.",J M Vargas-Muñiz 2015,2015,5 genes,Vargas-Muniz-2015-The Aspergillus fumigatus se,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6261,PHI:4896,UniProt,Q4WWT7,GenBank,EAL92866,,,Af293,aspE,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,septin,,,,unaffected pathogenicity,,,,,,wild type,,aberrant,,no,caspofungin; nikkomycin Z; micafungin,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,RP,26051489,PubMed,10.1016/j.fgb.2015.05.014,Fungal Genet Biol. 2015 Jun 5;81:41-51,bill.steinbach@duke.edu,"All the septins are dispensable in normal growth conditions, AspA, AspB, AspC and AspE are required for regular septation. Furthermore, deletion of only the core septin genes significantly reduced conidiation.",J M Vargas-Muñiz 2015,2015,5 genes,Vargas-Muniz-2015-The Aspergillus fumigatus se,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6262,PHI:4897,UniProt,Q9HVF6,GenBank,AE004878_1,,,PAO1,MgtC,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,macrophage subversion factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26080006,PubMed,10.1371/journal.ppat.1004969,PLoS Pathog. 2015 Jun 16;11(6):e1004969,anne.blanc-potard@univ-montp2.fr,"P. aeruginosa mgtC mutant is attenuated in the systemic infection model of zebrafish embryos, and strikingly, the attenuated phenotype is dependent on the presence of macrophages.",C Belon 2015,2015,1 gene,Belon-2015-A Macrophage Subversion Factor Is S,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6263,PHI:4898,UniProt,P9WM79,GenBank,CCP43312,,,H37Rv,Rv0574c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,coding for a polyglutamate synthase-like protein,,,,reduced virulence,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene disruption; gene complementation,,,RP,25312955,PubMed,10.1128/IAI.02274-14,Infect Immun. 2015 Jan;83(1):120-9,nirupamaban@yahoo.com,"The increased sensitivity of the mutant to antitubercular drugs, SDS, lysozyme, and mechanical stress was accompanied by a drastic reduction in the ability to form biofilm.",R Garg 2014,2014,1 gene,Garg-2014-A Conserved Hypothetical Protein Rv0,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6264,PHI:4899,UniProt,D0ZV89,GenBank,ACY87894,,,14028S,PhoQ,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,histidine kinase with a periplasmic sensor domain (PD) that promotes virulence by detecting the macrophage phagosome,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26002083,PubMed,10.7554/eLife.06792,Elife. 2015 May 23;4,millersi@uw.edu,"phoQ W104C-A128C Salmonella entericaTyphimurium is virulent in mice, indicating that acidic pH and divalent cation sensing by PhoQ are dispensable for virulence.",K G Hicks 2015,2015,1 gene,Hicks-2015-Acidic pH and divalent cation sensi,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6265,PHI:4900,UniProt,Q51380,GenBank,AAC44428,,,PAO1,crc,,,,,,,287,Pseudomonas aeruginosa,,PAO1001,nosocomial infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,post-transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26102536,PubMed,10.1016/j.jprot.2015.06.009,J Proteomics. 2015 Jun 21. pii: S1874-3919(15)30046-4,jlmtnez@cnb.csic.es,The crc mutant presented an impaired vesicle-associated secretion of quorum sensing signal molecules and less cytotoxicity than its wild-type strain.,J A Reales-Calderón 2015,2015,1 gene,Reales-Calderon-2015-Quantitative proteomics u,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6266,PHI:4901,UniProt,A6RTY1,GenBank,XP_001557620,,,B05.10,bcbrn1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,THN reductase,,,DHN (dihydroxy naphthalene) pathway,increased virulence (hypervirulence),,,,,,reduced,,aberrant; increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26035129,PubMed,10.1094/MPMI-04-15-0085-R,Mol Plant Microbe Interact. 2015 Jun 2,lxu@bio.ecnu.edu.cn,,C Zhang 2015,2015,2 genes,Zhang-2015-Loss of bcbrn1 and bcpks13 in Botry,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6267,PHI:4902,UniProt,A6SNM2,GenBank,XP_001547095,,,B05.10,bcpks13,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,polyketide synthase,,,DHN (dihydroxy naphthalene) pathway,increased virulence (hypervirulence),,,,,,reduced,,aberrant; increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26035129,PubMed,10.1094/MPMI-04-15-0085-R,Mol Plant Microbe Interact. 2015 Jun 2,lxu@bio.ecnu.edu.cn,,C Zhang 2015,2015,2 genes,Zhang-2015-Loss of bcbrn1 and bcpks13 in Botry,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6268,PHI:4901,UniProt,A6RTY1,GenBank,XP_001557620,,,B05.10,bcbrn1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,THN reductase,,,DHN (dihydroxy naphthalene) pathway,increased virulence (hypervirulence),,,,,,reduced,,aberrant; increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26035129,PubMed,10.1094/MPMI-04-15-0085-R,Mol Plant Microbe Interact. 2015 Jun 2,lxu@bio.ecnu.edu.cn,,C Zhang 2015,2015,2 genes,Zhang-2015-Loss of bcbrn1 and bcpks13 in Botry,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6269,PHI:4902,UniProt,A6SNM2,GenBank,XP_001547095,,,B05.10,bcpks13,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,polyketide synthase,,,DHN (dihydroxy naphthalene) pathway,increased virulence (hypervirulence),,,,,,reduced,,aberrant; increased,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26035129,PubMed,10.1094/MPMI-04-15-0085-R,Mol Plant Microbe Interact. 2015 Jun 2,lxu@bio.ecnu.edu.cn,,C Zhang 2015,2015,2 genes,Zhang-2015-Loss of bcbrn1 and bcpks13 in Botry,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6270,PHI:4901,UniProt,A6RTY1,GenBank,XP_001557620,,,B05.10,bcbrn1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,THN reductase,,,DHN (dihydroxy naphthalene) pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26035129,PubMed,10.1094/MPMI-04-15-0085-R,Mol Plant Microbe Interact. 2015 Jun 2,lxu@bio.ecnu.edu.cn,,C Zhang 2015,2015,2 genes,Zhang-2015-Loss of bcbrn1 and bcpks13 in Botry,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6271,PHI:4901,UniProt,A6RTY1,GenBank,XP_001557620,,,B05.10,bcbrn1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,THN reductase,,,DHN (dihydroxy naphthalene) pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26035129,PubMed,10.1094/MPMI-04-15-0085-R,Mol Plant Microbe Interact. 2015 Jun 2,lxu@bio.ecnu.edu.cn,,C Zhang 2015,2015,2 genes,Zhang-2015-Loss of bcbrn1 and bcpks13 in Botry,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6272,PHI:4903,UniProt,C4YN44,GenBank,EEQ44025,,,WO-1,Fdh3,,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,glutathione recycling enzymes/ S-nitrosoglutathione reductase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; CySNO; formaldehyde; DPTA NONOate,H2O2: CHEBI:16240; formaldehyde: CHEBI:16842; DPTA NONOate CAS: CAS:146724-95-0,,,,,gene disruption; gene complementation,,,RP,26039593,PubMed,10.1371/journal.pone.0126940,PLoS One. 2015 Jun 3;10(6):e0126940,al.brown@abdn.ac.uk,"GLR1 deletion increases the sensitivity ofC.albicanscells to H2O2, but not to formaldehyde or NO. FDH3 inactivation delays NO adaptation and increases NO sensitivity.",A T Tillmann 2015,2015,2 genes,Tillmann-2015-Contribution of Fdh3 and Glr1 to,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6273,PHI:4904,UniProt,C4YR40,GenBank,EEQ46193,,,WO-1,Glr1,,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,glutathione recycling enzymes/ glutathione reductase,,,,reduced virulence,,,,,,,,,,no,H2O2; CySNO; formaldehyde; DPTA NONOate,H2O2: CHEBI:16240; formaldehyde: CHEBI:16842; DPTA NONOate CAS: CAS:146724-95-0,,,,,gene disruption; gene complementation,,,RP,26039593,PubMed,10.1371/journal.pone.0126940,PLoS One. 2015 Jun 3;10(6):e0126940,al.brown@abdn.ac.uk,"GLR1 deletion increases the sensitivity ofC.albicanscells to H2O2, but not to formaldehyde or NO. FDH3 inactivation delays NO adaptation and increases NO sensitivity.",A T Tillmann 2015,2015,2 genes,Tillmann-2015-Contribution of Fdh3 and Glr1 to,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6274,PHI:4903,UniProt,C4YN44,GenBank,EEQ44025,,,WO-1,Fdh3,,,,,,,5476,Candida albicans,,,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glutathione recycling enzymes/ S-nitrosoglutathione reductase,,,,reduced virulence,,,,,,,,,,no,H2O2; CySNO; formaldehyde; DPTA NONOate,H2O2: CHEBI:16240; formaldehyde: CHEBI:16842; DPTA NONOate CAS: CAS:146724-95-0,,,,,gene disruption; gene complementation,,,RP,26039593,PubMed,10.1371/journal.pone.0126940,PLoS One. 2015 Jun 3;10(6):e0126940,al.brown@abdn.ac.uk,"GLR1 deletion increases the sensitivity ofC.albicanscells to H2O2, but not to formaldehyde or NO. FDH3 inactivation delays NO adaptation and increases NO sensitivity.",A T Tillmann 2015,2015,2 genes,Tillmann-2015-Contribution of Fdh3 and Glr1 to,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6275,PHI:4904,UniProt,C4YR40,GenBank,EEQ46193,,,WO-1,Glr1,,,,,,,5476,Candida albicans,,,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glutathione recycling enzymes/ glutathione reductase,,,,reduced virulence,,,,,,,,,,no,H2O2; CySNO; formaldehyde; DPTA NONOate,H2O2: CHEBI:16240; formaldehyde: CHEBI:16842; DPTA NONOate CAS: CAS:146724-95-0,,,,,gene disruption; gene complementation,,,RP,26039593,PubMed,10.1371/journal.pone.0126940,PLoS One. 2015 Jun 3;10(6):e0126940,al.brown@abdn.ac.uk,"GLR1 deletion increases the sensitivity ofC.albicanscells to H2O2, but not to formaldehyde or NO. FDH3 inactivation delays NO adaptation and increases NO sensitivity.",A T Tillmann 2015,2015,2 genes,Tillmann-2015-Contribution of Fdh3 and Glr1 to,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6276,PHI:4906,UniProt,Q5A679,GenBank,EAK98242,,,SC5314,Gyp1,,,,Myo2,UniProt: Q5AKW2,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,A golgi-associated protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,resistance,,gene mutation; gene complementation,,,RP,25326521,PubMed,10.1128/EC.00231-14,Eukaryot Cell. 2014 Dec;13(12):1548-56,mcbwangy@imcb.a-star.edu.sg,Proper PKA phosphorylation and GAP activity of Gyp1 are required for virulence in mice.,Z Huang 2014,2014,3 genes,Huang-2014-A Novel Mechanism Coupling cAMP-PKA,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6277,PHI:4907,UniProt,Q5A5Q9,GenBank,EAK98087,,,SC5314,GYP5,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,A golgi-associated protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,resistance,,gene mutation; gene complementation,,,RP,25326521,PubMed,10.1128/EC.00231-14,Eukaryot Cell. 2014 Dec;13(12):1548-56,mcbwangy@imcb.a-star.edu.sg,Proper PKA phosphorylation and GAP activity of Gyp1 are required for virulence in mice.,Z Huang 2014,2014,3 genes,Huang-2014-A Novel Mechanism Coupling cAMP-PKA,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6278,PHI:4908,UniProt,Q5AG64,GenBank,EAL01787,,,SC5314,GYP8,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,,A golgi-associated protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,resistance,,gene mutation; gene complementation,,,RP,25326521,PubMed,10.1128/EC.00231-14,Eukaryot Cell. 2014 Dec;13(12):1548-56,mcbwangy@imcb.a-star.edu.sg,Proper PKA phosphorylation and GAP activity of Gyp1 are required for virulence in mice.,Z Huang 2014,2014,3 genes,Huang-2014-A Novel Mechanism Coupling cAMP-PKA,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6279,PHI:4909,UniProt,G2WY50,GenBank,EGY21008,,,VdLs.17,VdQase,,,,,,,27337,Verticillium dahliae,,Vd9,vascular wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. Kennebec,,,root; stem,dioxygenase activity,,,jasmonic acid-pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26113857,PubMed,10.3389/fpls.2015.00440,Front Plant Sci. 2015 Jun 10;6:440,Fouad.Daayf@umanitoba.ca,The pathogenicity of VdQase knock-out mutants generated through Agrobacterium tumefasciens-mediated transformation was significantly reduced on susceptible potato cultivar Kennebec compared to wild type isolates,A El Hadrami 2015,2015,1 gene,El Hadrami-2015-A cupin domain-containing prot,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6280,PHI:4910,UniProt,Q7VMW0,GenBank,AAP95743,,,35000HP,LptA,,,,,,PHI:4911; PHI:4912,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,arm,PEA transferases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902140,PubMed,10.1371/journal.pone.0124373,PLoS One. 2015 Apr 22;10(4):e0124373,mebauer@iupui.edu,"In human inoculation experiments, the triple mutant was as virulent as its parent strain. While these mutants are resistant to alpha-defensins in H.ducreyi, our in vivo data suggest that resistance to cathelicidin may be more important than defensin resistance to H.ducreyi pathogenesis.",M P Trombley 2015,2015,3 genes,Trombley-2015-Phosphoethanolamine Transferase,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6281,PHI:4911,UniProt,Q7VNV7,GenBank,AAP95341,,,35000HP,PtdA,,,,,,PHI:4910; PHI:4912,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,arm,PEA transferases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902140,PubMed,10.1371/journal.pone.0124373,PLoS One. 2015 Apr 22;10(4):e0124373,mebauer@iupui.edu,"In human inoculation experiments, the triple mutant was as virulent as its parent strain. While these mutants are resistant to alpha-defensins in H.ducreyi, our in vivo data suggest that resistance to cathelicidin may be more important than defensin resistance to H.ducreyi pathogenesis.",M P Trombley 2015,2015,3 genes,Trombley-2015-Phosphoethanolamine Transferase,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6282,PHI:4912,UniProt,Q7VL81,GenBank,AAP96378,,,35000HP,PtdB,,,,,,PHI:4910; PHI:4911,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,arm,PEA transferases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902140,PubMed,10.1371/journal.pone.0124373,PLoS One. 2015 Apr 22;10(4):e0124373,mebauer@iupui.edu,"In human inoculation experiments, the triple mutant was as virulent as its parent strain. While these mutants are resistant to alpha-defensins in H.ducreyi, our in vivo data suggest that resistance to cathelicidin may be more important than defensin resistance to H.ducreyi pathogenesis.",M P Trombley 2015,2015,3 genes,Trombley-2015-Phosphoethanolamine Transferase,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6283,PHI:4913,UniProt,Q3S2Y8,GenBank,AAZ95526,,,J48,Srr2,,,,Fibrinogen; plasminogen,,,1311,Streptococcus agalactiae,,BM110,neonatal pneumonia; septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; brain,multifaceted adhesin,,,fibrinolysis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26094503,PubMed,10.1111/mmi.13097,Mol Microbiol. 2015 Jun 19,claire.poyart@cch.aphp.fr,"Srr2 increased bacterial survival to phagocytic killing and bacterial persistence in a murine model of meningitis. Srr2 is a multifaceted adhesin used by the ST-17 clone to hijack ligands of the host coagulation system, thereby contributing to bacterial dissemination and invasiveness, and ultimately to meningitis.",A Six 2015,2015,1 gene,"Six-2015-Srr2, a multifaceted adhesin expresse",BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6284,PHI:4914,UniProt,F9X691,GenBank,EGP89361,,,IPO323,ZtCBR1,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,microsomal cytochrome b5 reductase,,,,reduced virulence,,,,,,aberrant,,aberrant,,no,,,,,,,gene disruption,,,RP,26074495,PubMed,10.1016/j.fgb.2015.05.008,Fungal Genet Biol. 2015 Jun 11. pii: S1087-1845(15)00112-7,jason.rudd@rothamsted.ac.uk,Mutant strains exhibited delayed disease symptoms on wheat leaves and severely limited asexual sporulation. DZtCBR1 strains also exhibited aberrant spore morphology and hyphal growth in vitro.,M C Derbyshire 2015,2015,1 gene,Derbyshire-2015-Analysis of cytochrome b reduc,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6285,PHI:4915,UniProt,Q8YJ71,GenBank,AAL51397,,,16M,invA,,,,cathepsin D; calregulin,,,29459,Brucella melitensis,1229906,133,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,invasion and establishment of infection,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24667775,PubMed,10.4161/viru.28589,Virulence. 2014 May 15;5(4):563-74,fsg@unam.mx,In vivo infection results demonstrated that spleen colonization was significantly lower with the mutant than with the parental strain.,J alva-Pérez 2014,2014,1 gene,Alva-Perez-2014-The gene of is involved in int,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6286,PHI:4916,UniProt,A0A059SVJ2,GenBank,AHC56279,,,,MfPG1,,,,,,,38448,Monilinia fructicola,,MUK-1,blossom blight; fruit rot,eudicots,3760,Prunus persica (related: peach),cv. Tian Tao,,,petal,endopolygalacturonase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26120831,PubMed,10.1371/journal.pone.0132012,PLoS One. 2015 Jun 29;10(6):e0132012,mhlee@nchu.edu.tw,"MfPG1-overexpressing strains produced smaller lesions and higher levels of reactive oxygen species (ROS) on the petals of peach and rose flowers than the wild-type strain, suggesting that MfPG1 affecting fungal virulence might be in part resulted from the increase of ROS in the Prunus-M.fructicola interactions.",C Chou 2015,2015,1 gene,Chou-2015-Expression of Five Endopolygalacturo,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6287,PHI:4916,UniProt,A0A059SVJ2,GenBank,AHC56279,,,,MfPG1,,,,,,,38448,Monilinia fructicola,,MUK-1,blossom blight; fruit rot,eudicots,267246,Rosa odorata (related: tea rose),cv. Flaming Peace,,,petal,endopolygalacturonase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26120831,PubMed,10.1371/journal.pone.0132012,PLoS One. 2015 Jun 29;10(6):e0132012,mhlee@nchu.edu.tw,"MfPG1-overexpressing strains produced smaller lesions and higher levels of reactive oxygen species (ROS) on the petals of peach and rose flowers than the wild-type strain, suggesting that MfPG1 affecting fungal virulence might be in part resulted from the increase of ROS in the Prunus-M.fructicola interactions.",C Chou 2015,2015,1 gene,Chou-2015-Expression of Five Endopolygalacturo,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6288,PHI:4917,UniProt,J5JYY9,GenBank,EJP69628,,,ARSEF 2860,BbbqrA,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,beetles,7070,Tribolium castaneum (related: red flour beetle),,,,,"1,4-benzoquinone oxidoreductase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,26056261,PubMed,10.1073/pnas.1504552112,Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3651-60,keyhani@ufl.edu,,N Pedrini 2015,2015,1 gene,Pedrini-2015-Tenebrionid secretions and a fung,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6289,PHI:4917,UniProt,J5JYY9,GenBank,EJP69628,,,ARSEF 2860,BbbqrA,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,beetles,7070,Tribolium castaneum (related: red flour beetle),,,,,"1,4-benzoquinone oxidoreductase",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26056261,PubMed,10.1073/pnas.1504552112,Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3651-60,keyhani@ufl.edu,,N Pedrini 2015,2015,1 gene,Pedrini-2015-Tenebrionid secretions and a fung,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6290,PHI:4917,UniProt,J5JYY9,GenBank,EJP69628,,,ARSEF 2860,BbbqrA,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"1,4-benzoquinone oxidoreductase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,26056261,PubMed,10.1073/pnas.1504552112,Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3651-60,keyhani@ufl.edu,,N Pedrini 2015,2015,1 gene,Pedrini-2015-Tenebrionid secretions and a fung,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6291,PHI:4917,UniProt,J5JYY9,GenBank,EJP69628,,,ARSEF 2860,BbbqrA,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"1,4-benzoquinone oxidoreductase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26056261,PubMed,10.1073/pnas.1504552112,Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3651-60,keyhani@ufl.edu,,N Pedrini 2015,2015,1 gene,Pedrini-2015-Tenebrionid secretions and a fung,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6292,PHI:4917,UniProt,J5JYY9,GenBank,EJP69628,,,ARSEF 2860,BbbqrA,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,beetles,7048,Sitophilus oryzae (related: rice weevil),,,,,"1,4-benzoquinone oxidoreductase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,26056261,PubMed,10.1073/pnas.1504552112,Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3651-60,keyhani@ufl.edu,,N Pedrini 2015,2015,1 gene,Pedrini-2015-Tenebrionid secretions and a fung,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6293,PHI:4917,UniProt,J5JYY9,GenBank,EJP69628,,,ARSEF 2860,BbbqrA,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,beetles,7048,Sitophilus oryzae (related: rice weevil),,,,,"1,4-benzoquinone oxidoreductase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26056261,PubMed,10.1073/pnas.1504552112,Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3651-60,keyhani@ufl.edu,,N Pedrini 2015,2015,1 gene,Pedrini-2015-Tenebrionid secretions and a fung,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6294,PHI:4918,UniProt,B4EIW7,GenBank,CAR54235,,,J2315,atsR,,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,global virulence regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26045541,PubMed,10.1128/mBio.00679-15,MBio. 2015 Jun 4;6(3). pii: e00679-15,m.valvano@qub.ac.uk,,M Khodai-Kalaki 2015,2015,4 genes,Khodai-Kalaki-2015-Burkholderia cenocepacia Li,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6295,PHI:4919,UniProt,G7HHI8,GenBank,CDN60372,,,H111,arnT,,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,"polymyxin resistance protein ArnT, undecaprenyl phosphate-alpha-L-Ara4N transferase; melittin resistance protein PqaB",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26045541,PubMed,10.1128/mBio.00679-15,MBio. 2015 Jun 4;6(3). pii: e00679-15,m.valvano@qub.ac.uk,,M Khodai-Kalaki 2015,2015,4 genes,Khodai-Kalaki-2015-Burkholderia cenocepacia Li,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6296,PHI:4920,UniProt,Q6VR34,GenBank,AAQ96739,,,BC10,fliC,,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26045541,PubMed,10.1128/mBio.00679-15,MBio. 2015 Jun 4;6(3). pii: e00679-15,m.valvano@qub.ac.uk,,M Khodai-Kalaki 2015,2015,4 genes,Khodai-Kalaki-2015-Burkholderia cenocepacia Li,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6297,PHI:4921,UniProt,B4EDI5,GenBank,CAR50419,,,J2315,flmQ,,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,flagellin glycosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26045541,PubMed,10.1128/mBio.00679-15,MBio. 2015 Jun 4;6(3). pii: e00679-15,m.valvano@qub.ac.uk,,M Khodai-Kalaki 2015,2015,4 genes,Khodai-Kalaki-2015-Burkholderia cenocepacia Li,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6298,PHI:4918,UniProt,B4EIW7,GenBank,CAR54235,,,J2315,atsR,,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,global virulence regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26045541,PubMed,10.1128/mBio.00679-15,MBio. 2015 Jun 4;6(3). pii: e00679-15,m.valvano@qub.ac.uk,,M Khodai-Kalaki 2015,2015,4 genes,Khodai-Kalaki-2015-Burkholderia cenocepacia Li,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6299,PHI:4919,UniProt,G7HHI8,GenBank,CDN60372,,,H111,arnT,,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"polymyxin resistance protein ArnT, undecaprenyl phosphate-alpha-L-Ara4N transferase; melittin resistance protein PqaB",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26045541,PubMed,10.1128/mBio.00679-15,MBio. 2015 Jun 4;6(3). pii: e00679-15,m.valvano@qub.ac.uk,,M Khodai-Kalaki 2015,2015,4 genes,Khodai-Kalaki-2015-Burkholderia cenocepacia Li,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6300,PHI:4920,UniProt,Q6VR34,GenBank,AAQ96739,,,BC10,fliC,,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26045541,PubMed,10.1128/mBio.00679-15,MBio. 2015 Jun 4;6(3). pii: e00679-15,m.valvano@qub.ac.uk,,M Khodai-Kalaki 2015,2015,4 genes,Khodai-Kalaki-2015-Burkholderia cenocepacia Li,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6301,PHI:4921,UniProt,B4EDI5,GenBank,CAR50419,,,J2315,flmQ,,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,flagellin glycosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26045541,PubMed,10.1128/mBio.00679-15,MBio. 2015 Jun 4;6(3). pii: e00679-15,m.valvano@qub.ac.uk,,M Khodai-Kalaki 2015,2015,4 genes,Khodai-Kalaki-2015-Burkholderia cenocepacia Li,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6302,PHI:4922,UniProt,Q04MW6,GenBank,ABJ55243,,,D39,argGH,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,arginine synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,24338350,PubMed,10.1093/infdis/jit818,J Infect Dis. 2014 Jun 1;209(11):1781-91,d.vandeBeek@amc.uva.n,,J R Piet 2014,2014,1 gene,Piet-2014-Streptococcus pneumoniae Arginine Sy,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6303,PHI:4923,UniProt,D2TV59,GenBank,CBG91802,,,ICC168,picC,,,,,,,67825,Citrobacter rodentium,,DBS100,,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestine,serine protease autotransporter,,,,increased virulence (hypervirulence),,,,,,,,increased; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25895966,PubMed,10.1128/IAI.00025-15,Infect Immun. 2015 Apr 20. pii: IAI.00025-15,bvallance@cw.bc.ca,,K Bhullar 2015,2015,1 gene,Bhullar-2015-The serine protease autotransport,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6304,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6305,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. Creek White,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6306,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. SD43,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6307,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. GS73CO,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6308,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W570,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6309,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. SD44,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6310,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. SD45,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6311,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. FS8A,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6312,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. ND301,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6313,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. ND253,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6314,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. ND101,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6315,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. ND257,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6316,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. Pa760,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6317,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. NYRD4058,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6318,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. SD40,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6319,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. B75,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6320,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. GEMS-0009,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6321,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. P737M20,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6322,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64ARpp9,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6323,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. R225,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6324,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. H116,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6325,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. FS8B,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6326,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. B73,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6327,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. CML9,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6328,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. CML247,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6329,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. CML264,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6330,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. CML277,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6331,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. CML52,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6332,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. ML287,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6333,PHI:4924,UniProt,M2URZ2,GenBank,KJ664924,,,C5,ToxA,,,,,,,5016,Bipolaris maydis,701091,C5,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. G80,,,leaf,proteinaceous host-selective toxin,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26051492,PubMed,10.1016/j.fgb.2015.05.013,Fungal Genet Biol. 2015 Jun 4;81:12-24,Shunwen.Lu@ars.usda.gov,Cochliobolus heterostrophus is pathogen anamorph name,S Lu 2015,2015,1 gene,Lu-2015-A ToxA-like protein from Cochliobolus,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6334,PHI:4925,UniProt,Q8TG40,GenBank,AF466197_1,,,,Hbr1,,,,,,,5476,Candida albicans,,R8,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"A regulator of white-opaque switching, also a positive and negative regulator of hyphal invasion.",,,,reduced virulence,,,,,,,,aberrant,,no,farnesol,farnesol: CHEBI:28600,,,,,gene mutation,,,RP,26039220,PubMed,10.1371/journal.pone.0126919,PLoS One. 2015 Jun 3;10(6):e0126919.,droberts@helix.nih.gov,Farnesol addition to theHBR1 heterozygote under embedded conditions resulted in a consistent failure in cytokinesis.,M L Pendrak 2015,2015,1 gene,Pendrak-2015-Hbr1 Activates and Represses Hyph,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6335,PHI:4926,UniProt,I3VB56,GenBank,AFK76483,,,Isolate A,Rs-CRT,,,,,,,46012,Radopholus similis,,,,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,"Ca2+-binding multifunctional protein that plays key roles in the parasitism, immune evasion, reproduction and pathogenesis.",,,,reduced virulence,,,,,,,,,,no,,,,,resistance,,altered gene expression / gene regulation: silencing,,,RP,26061142,PubMed,10.1371/journal.pone.0129351,PLoS One. 2015 Jun 10;10(6):e0129351,xiehui@scau.edu.cn,,Y Li 2015,2015,1 gene,"Li-2015-A Nematode Calreticulin, Rs-CRT, Is a",BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6336,PHI:4927,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,,,,,,83560,Chlamydia muridarum,,CMUT3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,reproductive system,effector virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25287930,PubMed,10.1128/IAI.02576-14,Infect Immun. 2014 Dec;82(12):5327-35,Zhongg@uthscsa.edu,"Pgp4 is known to regulate pgp3 expression, while lack of Pgp3 does not significantly affect Pgp4 function. Thus Pgp3 is concluded to be an effector virulence factor and that lack of Pgp3 may be responsible for the attenuation in C. Muridarum pathogenicity.",Y Liu 2014,2014,3 genes,Liu-2014-Plasmid-encoded Pgp3 is a major virul,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6337,PHI:4928,UniProt,Q46440,GenBank,CAA55377,,,MoPn; NiggII,pgp4,,,,,,,83560,Chlamydia muridarum,,CMUT3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,reproductive system,"regulates the expression on Pgp3, the effector virulence factor",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25287930,PubMed,10.1128/IAI.02576-14,Infect Immun. 2014 Dec;82(12):5327-35,Zhongg@uthscsa.edu,"Pgp4 is known to regulate pgp3 expression, while lack of Pgp3 does not significantly affect Pgp4 function. Thus Pgp3 is concluded to be an effector virulence factor and that lack of Pgp3 may be responsible for the attenuation in C. Muridarum pathogenicity.",Y Liu 2014,2014,3 genes,Liu-2014-Plasmid-encoded Pgp3 is a major virul,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6338,PHI:4929,UniProt,Q46435,GenBank,CAA55372,,,MoPn; NiggII,pgp7,,,,,,,83560,Chlamydia muridarum,,CMUT3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,reproductive system,plasmid-encoded pathogenic determinant,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25287930,PubMed,10.1128/IAI.02576-14,Infect Immun. 2014 Dec;82(12):5327-35,Zhongg@uthscsa.edu,"Pgp4 is known to regulate pgp3 expression, while lack of Pgp3 does not significantly affect Pgp4 function. Thus Pgp3 is concluded to be an effector virulence factor and that lack of Pgp3 may be responsible for the attenuation in C. Muridarum pathogenicity.",Y Liu 2014,2014,3 genes,Liu-2014-Plasmid-encoded Pgp3 is a major virul,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6339,PHI:4930,UniProt,A4VXE2,GenBank,ABP90781,,,05ZYH33,SsTGase,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: pig),,,,,transglutaminase; virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26085092,PubMed,10.1074/jbc.M115.643338,J Biol Chem. 2015 Jun 17. pii: jbc.M115.643338,miniminiyuan@163.com,SsTGase is a novel virulence factor of Ss2 by acting as a TGase in dimer form.,J Yu 2015,2015,1 gene,Yu-2015-Functional and structural characteriza,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6340,PHI:4931,UniProt,A5CLR7,GenBank,CAM98538,,,NCPPB 382,chp-7,,,,,,,28447,Clavibacter michiganensis,,Cm15-2.0 sm,bacterial canker,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,serine protease effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,gene mutation; gene complementation,,,RP,26075829,PubMed,10.1094/MPMI-02-15-0036-R,Mol Plant Microbe Interact. 2015 Jun 15,jglazebr@umn.edu,,Y Lu 2015,2015,2 genes,Lu-2015-Putative Serine Protease Effectors of,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6341,PHI:4932,UniProt,A5CLZ4,GenBank,CAN00074,,,NCPPB 382,ChpG,,,,,,,28447,Clavibacter michiganensis,,Cm15-2.0 sm,bacterial canker,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,serine protease effectors,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,hypersensitive response,gene mutation; gene complementation,,,RP,26075829,PubMed,10.1094/MPMI-02-15-0036-R,Mol Plant Microbe Interact. 2015 Jun 15,jglazebr@umn.edu,,Y Lu 2015,2015,2 genes,Lu-2015-Putative Serine Protease Effectors of,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6342,PHI:4933,,no data found,,,,,,HasS,,,,,,,1314,Streptococcus pyogenes,,SF370,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; kidney; peritonium,hyaluronic acid capsule biosynthesis,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25287924,PubMed,10.1128/IAI.02035-14,Infect Immun. 2014 Dec;82(12):5293-307,nkorotkova@uky.edu,,M Falaleeva 2014,2014,1 gene,Falaleeva-2014-Transcription of the Streptococ,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6343,PHI:4934,UniProt,F2MR50,GenBank,AEA94424,,,OG1RF,epaB,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),IL-10<-/->,,,colon,group 2 glycosyl transferase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26067254,PubMed,10.1371/journal.ppat.1004911,PLoS Pathog. 2015 Jun 12;11(6):e1004911,dirk.haller@tum.de,,S Ocvirk 2015,2015,2 genes,Ocvirk-2015-Surface-Associated Lipoproteins Li,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6344,PHI:4935,UniProt,F2MMS3,GenBank,AEA94146,,,OG1RF,lgt,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),IL-10<-/->,,,colon,prolipoprotein diacylglyceryl transferase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26067254,PubMed,10.1371/journal.ppat.1004911,PLoS Pathog. 2015 Jun 12;11(6):e1004911,dirk.haller@tum.de,,S Ocvirk 2015,2015,2 genes,Ocvirk-2015-Surface-Associated Lipoproteins Li,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6345,PHI:4936,UniProt,Q59WW7,GenBank,EAK94921,,,SC5314,gpx31,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,birds,9031,Gallus gallus (related: chicken),,,,,glutathione peroxidase,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; KCl; CdSO4; AgNO3; Congo red; calcofluor white,KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; CdSO4: CHEBI:50292; AgNO3: CHEBI:32130; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,24625675,PubMed,10.1093/mmy/myt021,Med Mycol. 2014 Apr;52(3):223-39,Bernhard.Hube@hki-jena.de,"Despite the sensitivity to oxidative stress and phagocytes, these mutants were not affected in their virulence in the chicken embryo model of candidiasis",P Miramon 2014,2014,3 genes,Miramon-2014-A family of glutathione peroxidas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6346,PHI:4936,UniProt,Q59WW7,GenBank,EAK94921,,,SC5314,gpx31,,,,,,PHI:4937; PHI:4938,5476,Candida albicans,,BWP17,disseminated candidiasis,birds,9031,Gallus gallus (related: chicken),,,,,glutathione peroxidase,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; KCl; CdSO4; AgNO3; Congo red; calcofluor white,KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; CdSO4: CHEBI:50292; AgNO3: CHEBI:32130; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,24625675,PubMed,10.1093/mmy/myt021,Med Mycol. 2014 Apr;52(3):223-39,Bernhard.Hube@hki-jena.de,"Despite the sensitivity to oxidative stress and phagocytes, these mutants were not affected in their virulence in the chicken embryo model of candidiasis",P Miramon 2014,2014,3 genes,Miramon-2014-A family of glutathione peroxidas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6347,PHI:4937,UniProt,Q59WW8,GenBank,EAK94920,,,SC5314,gpx32,,,,,,PHI:4936; PHI:4938,5476,Candida albicans,,BWP17,disseminated candidiasis,birds,9031,Gallus gallus (related: chicken),,,,,glutathione peroxidase,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; KCl; CdSO4; AgNO3; Congo red; calcofluor white,KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; CdSO4: CHEBI:50292; AgNO3: CHEBI:32130; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,24625675,PubMed,10.1093/mmy/myt021,Med Mycol. 2014 Apr;52(3):223-39,Bernhard.Hube@hki-jena.de,"Despite the sensitivity to oxidative stress and phagocytes, these mutants were not affected in their virulence in the chicken embryo model of candidiasis",P Miramon 2014,2014,3 genes,Miramon-2014-A family of glutathione peroxidas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6348,PHI:4938,UniProt,Q59XR9,GenBank,EAK95224,,,SC5314,gpx33,,,,,,PHI:4936; PHI:4937,5476,Candida albicans,,BWP17,disseminated candidiasis,birds,9031,Gallus gallus (related: chicken),,,,,glutathione peroxidase,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; KCl; CdSO4; AgNO3; Congo red; calcofluor white,KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; CdSO4: CHEBI:50292; AgNO3: CHEBI:32130; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,24625675,PubMed,10.1093/mmy/myt021,Med Mycol. 2014 Apr;52(3):223-39,Bernhard.Hube@hki-jena.de,"Despite the sensitivity to oxidative stress and phagocytes, these mutants were not affected in their virulence in the chicken embryo model of candidiasis",P Miramon 2014,2014,3 genes,Miramon-2014-A family of glutathione peroxidas,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6349,PHI:4939,UniProt,B2SVB9,GenBank,ACD58413,,,PXO99A,PXO_00049,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,cyclic di-GMP binding and regulation of virulence and motility,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25911481,PubMed,10.1128/AEM.04044-14,Appl Environ Microbiol. 2015 Jul 1;81(13):4358-67,cyhe@caas.net.cn,"Gene deletion of PXO_00049 and PXO_02374 resulted in significant increases in virulence andhrpgene transcription, indicating their negative regulation of virulence via type III secretion system expression.",F Yang 2015,2015,2 genes,Yang-2015-The Xanthomonas oryzae pv. oryzae Pi,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6350,PHI:4940,UniProt,B2SLL6,GenBank,ACD60665,,,PXO99A,PXO_02374,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,cyclic di-GMP binding and regulation of virulence and motility,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25911481,PubMed,10.1128/AEM.04044-14,Appl Environ Microbiol. 2015 Jul 1;81(13):4358-67,cyhe@caas.net.cn,"Gene deletion of PXO_00049 and PXO_02374 resulted in significant increases in virulence andhrpgene transcription, indicating their negative regulation of virulence via type III secretion system expression.",F Yang 2015,2015,2 genes,Yang-2015-The Xanthomonas oryzae pv. oryzae Pi,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6351,PHI:4941,UniProt,I1RW16,GenBank,ESU14872,,,PH-1,cdc2A,,,,FgCak1,UniProt: I1RLX6; GenBank: ESU10842,PHI:4942,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,cell cycle progression,,,,lethal,,,,,,wild type,,wild type,,yes,,,,,,,gene mutation,,,RP,26083253,PubMed,10.1371/journal.ppat.1004913,PLoS Pathog. 2015 Jun 17;11(6):e1004913,jinrong@purdue.edu,"The cdc2A and cdc2B mutants also were normal in response to oxidative, hyperosmotic, cell wall, and membrane stresses.",H Liu 2015,2015,2 genes,Liu-2015-Two Cdc2 Kinase Genes with Distinct F,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6352,PHI:4942,UniProt,A0A0E0S2Z7,EMBL,FGRAMPH1_01T12137,,,PH-1,cdc2B,,,,FgCak1,UniProt: I1RLX6; GenBank: ESU10842,PHI:4941,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,cell cycle progression,,,,lethal,,,,,,wild type,,wild type,,yes,,,,,,,gene mutation,,,RP,26083253,PubMed,10.1371/journal.ppat.1004913,PLoS Pathog. 2015 Jun 17;11(6):e1004913,jinrong@purdue.edu,"The cdc2A and cdc2B mutants also were normal in response to oxidative, hyperosmotic, cell wall, and membrane stresses.",H Liu 2015,2015,2 genes,Liu-2015-Two Cdc2 Kinase Genes with Distinct F,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6353,PHI:4941,UniProt,I1RW16,GenBank,ESU14872,,,PH-1,cdc2A,,,,FgCak1,UniProt: I1RLX6; GenBank: ESU10842,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,cell cycle progression,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26083253,PubMed,10.1371/journal.ppat.1004913,PLoS Pathog. 2015 Jun 17;11(6):e1004913,jinrong@purdue.edu,"The cdc2A and cdc2B mutants also were normal in response to oxidative, hyperosmotic, cell wall, and membrane stresses.",H Liu 2015,2015,2 genes,Liu-2015-Two Cdc2 Kinase Genes with Distinct F,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6354,PHI:4942,UniProt,A0A0E0S2Z7,EMBL,FGRAMPH1_01T12137,,,PH-1,cdc2B,,,,FgCak1,UniProt: I1RLX6; GenBank: ESU10842,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spikelet,cell cycle progression,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26083253,PubMed,10.1371/journal.ppat.1004913,PLoS Pathog. 2015 Jun 17;11(6):e1004913,jinrong@purdue.edu,"The cdc2A and cdc2B mutants also were normal in response to oxidative, hyperosmotic, cell wall, and membrane stresses.",H Liu 2015,2015,2 genes,Liu-2015-Two Cdc2 Kinase Genes with Distinct F,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6355,PHI:4943,UniProt,F9X7N2,GenBank,XP_003853696,,,IPO323,KU70,chromosome 3,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Avalon,,,leaf,cell cycle progression,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,26092796,PubMed,10.1016/j.fgb.2015.04.015,Fungal Genet Biol. 2015 Jun;79:102-9,k.haynes@exeter.ac.uk,,Y S Sidhu 2015,2015,2 genes,Sidhu-2015-Exploitation of sulfonylurea resist,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6356,PHI:4944,UniProt,F9X9S4,GenBank,EGP88062,,,IPO323,KU80,chromosome 4,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Avalon,,,leaf,cell cycle progression,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,26092796,PubMed,10.1016/j.fgb.2015.04.015,Fungal Genet Biol. 2015 Jun;79:102-9,k.haynes@exeter.ac.uk,,Y S Sidhu 2015,2015,2 genes,Sidhu-2015-Exploitation of sulfonylurea resist,BATCH_050,2015-07-01,MC,,,,,,,,,,,,,
,,Record 6357,PHI:3500,,no data found,GenBank,GR304380,,,CYR31,PsANT,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici strain CYR31,yellow rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Shuiyuan 11,,,leaf,adenine nucleotide translocase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26058921,PubMed,10.1038/srep11241,Sci Rep. 2015 Jun 10;5:11241,kangzs@nwsuaf.edu.cn,"Over-expression of PsANTindicated that PsANTpromotes cell death in tobacco, wheat and fission yeast cells / Knockdown of PsANTusing a host-induced gene silencing system (HIGS) attenuated the growth and development of virulent Pstat the early infection stage but not enough to alter its pathogenicity.",C Tang 2015,2015,1 gene,"Tang-2015-PsANT, the adenine nucleotide transl",BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6358,PHI:4945,,no data found,GenBank,AB05243.1,,,,AbGTT1.2,,,,,,,29001,Alternaria brassicicola,,Abra43,black spot,eudicots,3712,Brassica oleracea (no common name found),cv. Bartolo,,,leaf,glutathione transferases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26081847,PubMed,10.1186/s12866-015-0462-0,BMC Microbiol. 2015 Jun 18;15:123,philippe.simoneau@univ-angers.fr,,B Calmes 2015,2015,5 genes,Calmes-2015-Characterization of glutathione tr,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6359,PHI:4946,,no data found,GenBank,AB07364.1,,,,AbGSTFuA1,,,,,,,29001,Alternaria brassicicola,,Abra43,black spot,eudicots,3712,Brassica oleracea (no common name found),cv. Bartolo,,,leaf,glutathione transferases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26081847,PubMed,10.1186/s12866-015-0462-0,BMC Microbiol. 2015 Jun 18;15:123,philippe.simoneau@univ-angers.fr,,B Calmes 2015,2015,5 genes,Calmes-2015-Characterization of glutathione tr,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6360,PHI:4947,,no data found,GenBank,AB04746.1,,,,AbGSTO1,,,,,,,29001,Alternaria brassicicola,,Abra43,black spot,eudicots,3712,Brassica oleracea (no common name found),cv. Bartolo,,,leaf,glutathione transferases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26081847,PubMed,10.1186/s12866-015-0462-0,BMC Microbiol. 2015 Jun 18;15:123,philippe.simoneau@univ-angers.fr,,B Calmes 2015,2015,5 genes,Calmes-2015-Characterization of glutathione tr,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6361,PHI:4948,,no data found,GenBank,AB08663.1,,,,AbMAPEG1,,,,,,,29001,Alternaria brassicicola,,Abra43,black spot,eudicots,3712,Brassica oleracea (no common name found),cv. Bartolo,,,leaf,glutathione transferases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26081847,PubMed,10.1186/s12866-015-0462-0,BMC Microbiol. 2015 Jun 18;15:123,philippe.simoneau@univ-angers.fr,,B Calmes 2015,2015,5 genes,Calmes-2015-Characterization of glutathione tr,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6362,PHI:4949,,no data found,GenBank,AB09895.1,,,,AbUre2pB1,,,,,,,29001,Alternaria brassicicola,,Abra43,black spot,eudicots,3712,Brassica oleracea (no common name found),cv. Bartolo,,,leaf,glutathione transferases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26081847,PubMed,10.1186/s12866-015-0462-0,BMC Microbiol. 2015 Jun 18;15:123,philippe.simoneau@univ-angers.fr,,B Calmes 2015,2015,5 genes,Calmes-2015-Characterization of glutathione tr,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6363,PHI:4950,UniProt,A0A0B6NWQ3,GenBank,AJJ87827,,,CO92,feoB,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,ferrous iron transport protein B,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6364,PHI:4951,UniProt,A0A0B6P483,GenBank,AJJ89743,,,CO92,yfeAB,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,periplasmic solute binding family protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6365,PHI:4950,UniProt,A0A0B6NWQ3,GenBank,AJJ87827,,,CO92,feoB,,,,,,PHI:4951,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,ferrous iron transport protein B,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6366,PHI:4951,UniProt,A0A0B6P483,GenBank,AJJ89743,,,CO92,yfeAB,,,,,,PHI:4950,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,periplasmic solute binding family protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6367,PHI:4952,UniProt,A0A0B6NL56,GenBank,AJJ86770,,,CO92,znu,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,high-affinity zinc uptake system protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6368,PHI:4953,UniProt,Q7CI41,GenBank,AE013843_2,,,KIM10+,irp2,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,nonribosomal peptide synthetase,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6369,PHI:4954,UniProt,A0A0B6P199,GenBank,AJJ88688,,,CO92,mntH,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,manganese transport protein mntH,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6370,PHI:4951,UniProt,A0A0B6P483,GenBank,AJJ89743,,,CO92,yfeAB,,,,,,PHI:4954,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,periplasmic solute binding family protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6371,PHI:4954,UniProt,A0A0B6P199,GenBank,AJJ88688,,,CO92,mntH,,,,,,PHI:4951,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,manganese transport protein mntH,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6372,PHI:4955,UniProt,P46359,GenBank,CAA84487,,,6/69,psn,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,iron binding,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6373,PHI:4952,UniProt,A0A0B6NL56,GenBank,AJJ86770,,,CO92,znu,,,,,,PHI:4953,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,high-affinity zinc uptake system protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6374,PHI:4953,UniProt,Q7CI41,GenBank,AE013843_2,,,KIM10+,irp2,,,,,,PHI:4952,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,nonribosomal peptide synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6375,PHI:4955,UniProt,P46359,GenBank,CAA84487,,,6/69,psn,,,,,,PHI:4952,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,iron binding,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6376,PHI:4952,UniProt,A0A0B6NL56,GenBank,AJJ86770,,,CO92,znu,,,,,,PHI:4955,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,high-affinity zinc uptake system protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,25891079,PubMed,10.1039/c4mt00332b,Metallomics. 2015 Jun 10;7(6):965-78,rperry@uky.edu,,R D Perry 2015,2015,6 genes,Perry-2015-The role of transition metal transp,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6377,PHI:4956,UniProt,B2SMH5,GenBank,ACD59175,,,PXO99A,PXO_00987,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,acetyltransferase in theflagellar regulon,,,,reduced virulence,,,,,shorter lesions,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26065383,PubMed,10.1016/j.micpath.2015.06.001,Microb Pathog. 2015 Aug;85:50-7,ftian@ippcaas.cn,,H Li 2015,2015,1 gene,"Li-2015-PXO_00987, a putative acetyltransferas",BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6378,PHI:4957,UniProt,I6X8R2,GenBank,AIR12922,,,H37Rv,Zmp1,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,peptidase M13,,,endothelin receptor signaling,increased virulence (hypervirulence),,,,,shorter lesions,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,25267836,PubMed,10.1128/IAI.02304-14,Infect Immun. 2014 Dec;82(12):5154-65,apkipnis@gmail.com,Blocking endothelin receptor signaling during M. tuberculosis infection causes increased severity of lesions and bacterial loads in the lungs.,A F Correa 2014,2014,1 gene,Correa-2014-Endothelin system has a significan,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6379,PHI:4958,UniProt,Q572D3,GenBank,ADC96691,,,Haplotype 1,Avr3a,,,,,,,4787,Phytophthora infestans,,HP10-45,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),HP10-45,,,leaf,RXLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26077032,PubMed,10.1007/s10142-015-0446-z,Funct Integr Genomics. 2015 Jun 16,sundareshas8@gmail.com,,S Sanju 2015,2015,1 gene,Sanju-2015-Host-mediated gene silencing of a s,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6380,PHI:4959,UniProt,G7SLQ9,GenBank,AER20951,,,ST1,sly,,,,,,,1307,Streptococcus suis,1004951,ST1,meningitis,rodents,10090,Mus musculus (related: house mouse),A/J,,,blood; brain,"suilysin, a member of cholesterol-dependent cytolysins",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,24285845,PubMed,10.1093/infdis/jit661,J Infect Dis. 2014 May 15;209(10):1509-19,dantake@biken.osaka-u.ac.jp,"Differential transcriptional levels of suilysin in ST1 and ST104 strains, resulted in different in vitro pathogenicity.",D Takeuchi 2014,2014,1 gene,Takeuchi-2014-The Contribution of Suilysin to,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6381,PHI:4960,UniProt,A0A0H3JLK2,GenBank,BAB41677,,,N315,rsmI,,RN4220deltarsmI::pT0447; Cmr,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,moths,7091,Bombyx mori (related: domestic silkworm),,,,,ribosomal RNA small subunit methyltransferase I,,,,reduced virulence,,,,,,,,reduced,,no,N-acetyl-L-cysteine; menadione; paraquat; H2O2,N-acetyl-L-cysteine: CHEBI:28939; menadione: CHEBI:28869; paraquat: CHEBI:34905; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25893373,PubMed,10.1111/febs.13302,FEBS J. 2015 Jul;282(13):2570-84,kaito@mol.f.u-tokyo.ac.jp,"Deletion of either rsmI or rsmH in S. aureus attenuated the virulence ofS. aureusin silkworms, and led to its sensitivity to oxidative stress.",T Kyuma 2015,2015,2 genes,Kyuma-2015-Ribosomal RNA methyltransferases co,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6382,PHI:4961,UniProt,P60392,GenBank,BAB42274,,,N315,rsmH,,RN4220deltarsmH::aph;Kmr,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,moths,7091,Bombyx mori (related: domestic silkworm),,,,,ribosomal RNA small subunit methyltransferase H,,,,reduced virulence,,,,,,,,reduced,,no,N-acetyl-L-cysteine; menadione; paraquat; H2O2,N-acetyl-L-cysteine: CHEBI:28939; menadione: CHEBI:28869; paraquat: CHEBI:34905; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,25893373,PubMed,10.1111/febs.13302,FEBS J. 2015 Jul;282(13):2570-84,kaito@mol.f.u-tokyo.ac.jp,"Deletion of either rsmI or rsmH in S. aureus attenuated the virulence ofS. aureusin silkworms, and led to its sensitivity to oxidative stress.",T Kyuma 2015,2015,2 genes,Kyuma-2015-Ribosomal RNA methyltransferases co,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6383,PHI:4962,UniProt,G4NLK8,GenBank,EHA46061,,,70-15,TWL,chromosome 7,,,Swr1; Sin3; Csn; Thnr,"Swr1, UniProt: G4MP79; Sin3, UniProt: G4N744; Csn, UniProt: G4N324; Thnr, UniProt: Q12634",,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,circadian-regulated twilight (TWL) function essential for phototropic induction of asexual development and pathogenesis.,,,,reduced virulence,,,,yes,,reduced,,wild type,,no,menadione; H2O2,menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26102503,PubMed,10.1371/journal.ppat.1004972,PLoS Pathog. 2015 Jun 23;11(6):e1004972,naweed@tll.org.sg,,Y Z Deng 2015,2015,1 gene,"Deng-2015-Twilight, a Novel Circadian-Regulate",BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6384,PHI:4962,UniProt,G4NLK8,GenBank,EHA46061,,,70-15,TWL,chromosome 7,,,Swr1; Sin3; Csn; Thnr,"Swr1, UniProt: G4MP79; Sin3, UniProt: G4N744; Csn, UniProt: G4N324; Thnr, UniProt: Q12634",,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,circadian-regulated twilight (TWL) function essential for phototropic induction of asexual development and pathogenesis.,,,,reduced virulence,,,,yes,,reduced,,wild type,,no,menadione; H2O2,menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26102503,PubMed,10.1371/journal.ppat.1004972,PLoS Pathog. 2015 Jun 23;11(6):e1004972,naweed@tll.org.sg,,Y Z Deng 2015,2015,1 gene,"Deng-2015-Twilight, a Novel Circadian-Regulate",BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6385,PHI:4963,UniProt,I6YE93,GenBank,AFN52237,,,JF09,TcdA,,,,,,,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),Hines,,,,exotoxins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26037121,PubMed,10.1128/mBio.00551-15,MBio. 2015 Jun 2;6(3):e00551,Dena.Lyras@monash.edu,"TcdB alone is associated with both severe localized intestinal damage and systemic organ damage, suggesting that this toxin might be responsible for the onset of multiple organ dysfunction syndrome (MODS), a poorly characterized but often fatal complication ofC. difficileinfection (CDI). Pathogen formerly called Clostridium difficile",G P Carter 2015,2015,2 genes,Carter-2015-Defining the Roles of TcdA and Tcd,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6386,PHI:4964,UniProt,P18177,GenBank,CAA37298,,,VPI 10463,TcdB,,,,,,,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),Hines,,,,exotoxins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26037121,PubMed,10.1128/mBio.00551-15,MBio. 2015 Jun 2;6(3):e00551,Dena.Lyras@monash.edu,"TcdB alone is associated with both severe localized intestinal damage and systemic organ damage, suggesting that this toxin might be responsible for the onset of multiple organ dysfunction syndrome (MODS), a poorly characterized but often fatal complication ofC. difficileinfection (CDI). Pathogen formerly called Clostridium difficile",G P Carter 2015,2015,2 genes,Carter-2015-Defining the Roles of TcdA and Tcd,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6387,PHI:4963,UniProt,I6YE93,GenBank,AFN52237,,,JF09,TcdA,,,,,,PHI:4964,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),Hines,,,,exotoxins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26037121,PubMed,10.1128/mBio.00551-15,MBio. 2015 Jun 2;6(3):e00551,Dena.Lyras@monash.edu,"TcdB alone is associated with both severe localized intestinal damage and systemic organ damage, suggesting that this toxin might be responsible for the onset of multiple organ dysfunction syndrome (MODS), a poorly characterized but often fatal complication ofC. difficileinfection (CDI). Pathogen formerly called Clostridium difficile",G P Carter 2015,2015,2 genes,Carter-2015-Defining the Roles of TcdA and Tcd,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6388,PHI:4964,UniProt,P18177,GenBank,CAA37298,,,VPI 10463,TcdB,,,,,,PHI:4963,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),Hines,,,,exotoxins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26037121,PubMed,10.1128/mBio.00551-15,MBio. 2015 Jun 2;6(3):e00551,Dena.Lyras@monash.edu,"TcdB alone is associated with both severe localized intestinal damage and systemic organ damage, suggesting that this toxin might be responsible for the onset of multiple organ dysfunction syndrome (MODS), a poorly characterized but often fatal complication ofC. difficileinfection (CDI). Pathogen formerly called Clostridium difficile",G P Carter 2015,2015,2 genes,Carter-2015-Defining the Roles of TcdA and Tcd,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6389,PHI:4963,UniProt,I6YE93,GenBank,AFN52237,,,JF09,TcdA,,,,,,,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),Hines model,,,,exotoxins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26037121,PubMed,10.1128/mBio.00551-15,MBio. 2015 Jun 2;6(3):e00551,Dena.Lyras@monash.edu,"TcdB alone is associated with both severe localized intestinal damage and systemic organ damage, suggesting that this toxin might be responsible for the onset of multiple organ dysfunction syndrome (MODS), a poorly characterized but often fatal complication ofC. difficileinfection (CDI). Pathogen formerly called Clostridium difficile",G P Carter 2015,2015,2 genes,Carter-2015-Defining the Roles of TcdA and Tcd,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6390,PHI:4964,UniProt,P18177,GenBank,CAA37298,,,VPI 10463,TcdB,,,,,,,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),Hines model,,,,exotoxins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26037121,PubMed,10.1128/mBio.00551-15,MBio. 2015 Jun 2;6(3):e00551,Dena.Lyras@monash.edu,"TcdB alone is associated with both severe localized intestinal damage and systemic organ damage, suggesting that this toxin might be responsible for the onset of multiple organ dysfunction syndrome (MODS), a poorly characterized but often fatal complication ofC. difficileinfection (CDI). Pathogen formerly called Clostridium difficile",G P Carter 2015,2015,2 genes,Carter-2015-Defining the Roles of TcdA and Tcd,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6391,PHI:4963,UniProt,I6YE93,GenBank,AFN52237,,,JF09,TcdA,,,,,,PHI:4964,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),Hines model,,,,exotoxins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26037121,PubMed,10.1128/mBio.00551-15,MBio. 2015 Jun 2;6(3):e00551,Dena.Lyras@monash.edu,"TcdB alone is associated with both severe localized intestinal damage and systemic organ damage, suggesting that this toxin might be responsible for the onset of multiple organ dysfunction syndrome (MODS), a poorly characterized but often fatal complication ofC. difficileinfection (CDI). Pathogen formerly called Clostridium difficile",G P Carter 2015,2015,2 genes,Carter-2015-Defining the Roles of TcdA and Tcd,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6392,PHI:4964,UniProt,P18177,GenBank,CAA37298,,,VPI 10463,TcdB,,,,,,PHI:4963,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),Hines model,,,,exotoxins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26037121,PubMed,10.1128/mBio.00551-15,MBio. 2015 Jun 2;6(3):e00551,Dena.Lyras@monash.edu,"TcdB alone is associated with both severe localized intestinal damage and systemic organ damage, suggesting that this toxin might be responsible for the onset of multiple organ dysfunction syndrome (MODS), a poorly characterized but often fatal complication ofC. difficileinfection (CDI). Pathogen formerly called Clostridium difficile",G P Carter 2015,2015,2 genes,Carter-2015-Defining the Roles of TcdA and Tcd,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6393,PHI:4965,UniProt,Q06131,GenBank,AAA72322,,,YPIII(pIB1),YopD,,,,YopB,UniProt: Q06114,,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,minor translocator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,RP,25807250,PubMed,10.1371/journal.pone.0130112,PLoS One. 2015 Jun 12;10(6):e0130112,gloria.viboud@stonybrook.edu,,R Solomon 2015,2015,1 gene,Solomon-2015-Random Mutagenesis Identifies a C,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6394,PHI:4966,UniProt,F9WWR1,GenBank,EGP92150,,,IPO323,sdi1,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Galaxie,,,leaf,succinate dehydrogenase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,26092798,PubMed,10.1016/j.fgb.2015.03.018,Fungal Genet Biol. 2015 Jun;79:118-24,G.Steinberg@exeter.ac.uk,,S Kilaru 2015,2015,1 gene,Kilaru-2015-A gene locus for targeted ectopic,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6395,PHI:4967,UniProt,A0FDY3,GenBank,ABK13738,,,1212R,HopZ1a,,,,IP6,,,317,Pseudomonas syringae,,,,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26103463,PubMed,10.1111/nph.13528,New Phytol. 2015 Jun 23,wenboma@ucr.edu,The serine mutations abolish the acetyltransferase activity of the gene.,K Ma 2015,2015,3 genes,Ma-2015-Two serine residues in Pseudomonas syr,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6396,PHI:4968,UniProt,Q4ZX47,GenBank,AAY36275,,,B728a,HopZ3,,,,,,,317,Pseudomonas syringae,,,,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26103463,PubMed,10.1111/nph.13528,New Phytol. 2015 Jun 23,wenboma@ucr.edu,The serine mutations abolish the acetyltransferase activity of the gene.,K Ma 2015,2015,3 genes,Ma-2015-Two serine residues in Pseudomonas syr,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6397,PHI:4969,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,PopP2,,,,,,,305,Ralstonia solanacearum,,,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26103463,PubMed,10.1111/nph.13528,New Phytol. 2015 Jun 23,wenboma@ucr.edu,The serine mutations abolish the acetyltransferase activity of the gene.,K Ma 2015,2015,3 genes,Ma-2015-Two serine residues in Pseudomonas syr,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6398,PHI:4970,UniProt,Q6WIH5,GenBank,AAQ21097,,,,MEP1,,,,,,,523103,Trichophyton mentagrophytes,,360-A,ringworm,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,skin,metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23859078,PubMed,10.3109/13693786.2013.811552,Med Mycol. 2014 Jan;52(1):36-45,yipengjin@sina.com,,X Zhang 2013,2013,5 genes,Zhang-2013-Metalloprotease genes of Trichophyt,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6399,PHI:4971,UniProt,Q6WIH2,GenBank,AAQ21100,,,,MEP2,,,,,,,523103,Trichophyton mentagrophytes,,360-A,ringworm,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,skin,metalloprotease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23859078,PubMed,10.3109/13693786.2013.811552,Med Mycol. 2014 Jan;52(1):36-45,yipengjin@sina.com,,X Zhang 2013,2013,5 genes,Zhang-2013-Metalloprotease genes of Trichophyt,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6400,PHI:4972,UniProt,Q6WIH3,GenBank,AAQ21099,,,,MEP3,,,,,,,523103,Trichophyton mentagrophytes,,360-A,ringworm,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,skin,metalloprotease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23859078,PubMed,10.3109/13693786.2013.811552,Med Mycol. 2014 Jan;52(1):36-45,yipengjin@sina.com,,X Zhang 2013,2013,5 genes,Zhang-2013-Metalloprotease genes of Trichophyt,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6401,PHI:4973,UniProt,Q6WIH1,GenBank,AAQ21101,,,,MEP4,,,,,,,523103,Trichophyton mentagrophytes,,360-A,ringworm,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,skin,metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23859078,PubMed,10.3109/13693786.2013.811552,Med Mycol. 2014 Jan;52(1):36-45,yipengjin@sina.com,,X Zhang 2013,2013,5 genes,Zhang-2013-Metalloprotease genes of Trichophyt,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6402,PHI:4974,UniProt,Q6WIH6,GenBank,AAQ21096,,,,MEP5,,,,,,,523103,Trichophyton mentagrophytes,,360-A,ringworm,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,skin,metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,23859078,PubMed,10.3109/13693786.2013.811552,Med Mycol. 2014 Jan;52(1):36-45,yipengjin@sina.com,,X Zhang 2013,2013,5 genes,Zhang-2013-Metalloprotease genes of Trichophyt,BATCH_050B,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6403,PHI:4975,UniProt,Q5WWE3,GenBank,CAH15750,,,Lens,LssB,,,,,,PHI:4976,446,Legionella pneumophila,297246,Paris,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,functional type 1 secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,25422301,PubMed,10.1128/JB.02164-14,J Bacteriol. 2015 Feb;197(3):563-71,christophe.gilbert.bio@univ-lyon1.fr,,F Fuche 2014,2014,3 genes,Fuche-2014-Functional type 1 secretion system,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6404,PHI:4976,UniProt,Q83XM0,GenBank,CAD90950,,,Corby,LssD,,,,,,PHI:4975,446,Legionella pneumophila,297246,Paris,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,functional type 1 secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,25422301,PubMed,10.1128/JB.02164-14,J Bacteriol. 2015 Feb;197(3):563-71,christophe.gilbert.bio@univ-lyon1.fr,,F Fuche 2014,2014,3 genes,Fuche-2014-Functional type 1 secretion system,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6405,PHI:4977,UniProt,Q5WYQ5,GenBank,CAH14915,,,Lens,RtxA,,,,,,,446,Legionella pneumophila,297246,Paris,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,functional type 1 secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,25422301,PubMed,10.1128/JB.02164-14,J Bacteriol. 2015 Feb;197(3):563-71,christophe.gilbert.bio@univ-lyon1.fr,,F Fuche 2014,2014,3 genes,Fuche-2014-Functional type 1 secretion system,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6406,PHI:4978,UniProt,M7U578,GenBank,EMR88730,,,BcDW1,BcFRQ1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,circadian oscillator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,26124115,PubMed,10.1073/pnas.1508432112,Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8744-9,llarrondo@bio.puc.cl,"The deltabcfrq1 mutant presents decreased macroconidiation, enhanced sclerotia formation, and impaired virulence that Is dependent on the composition of the culture media.",M A Hevia 2015,2015,1 gene,Hevia-2015-A circadian oscillator in the fungu,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6407,PHI:4978,UniProt,M7U578,GenBank,EMR88730,,,BcDW1,BcFRQ1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,circadian oscillator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26124115,PubMed,10.1073/pnas.1508432112,Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8744-9,llarrondo@bio.puc.cl,"The deltabcfrq1 mutant presents decreased macroconidiation, enhanced sclerotia formation, and impaired virulence that Is dependent on the composition of the culture media.",M A Hevia 2015,2015,1 gene,Hevia-2015-A circadian oscillator in the fungu,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6408,PHI:4979,UniProt,C4B8B7,GenBank,BAH59485,,,Ina168,AVR-Pii,,,,,,,318829,Magnaporthe oryzae,,Sasa2,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sasanishiki,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,OsExo70-F2,Ensembl: Os02g0505400; UniProt: Q6K647,resistance,,functional test in host: direct injection,,,RP,26186703,PubMed,10.1111/tpj.12934,Plant J. 2015 Jul 17,terauchi@ibrc.or.jp,"AVR-Pii interaction with OsExo70-F3seems to play a crucial role in effector triggered immunity by Pii, suggesting the role of OsExo70 as decoy or helper in Pii/AVR-Pii interactions.",K Fujisaki 2015,2015,1 gene,Fujisaki-2015-Rice Exo70 interacts with a fung,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6409,PHI:4979,UniProt,C4B8B7,GenBank,BAH59485,,,Ina168,AVR-Pii,,,,,,,318829,Magnaporthe oryzae,,Sasa2,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sasanishiki,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,OsExo70-F3,Ensembl: Os04g0382200; UniProt: Q7XVB9,resistance,,functional test in host: direct injection,,,RP,26186703,PubMed,10.1111/tpj.12934,Plant J. 2015 Jul 17,terauchi@ibrc.or.jp,"AVR-Pii interaction with OsExo70-F3seems to play a crucial role in effector triggered immunity by Pii, suggesting the role of OsExo70 as decoy or helper in Pii/AVR-Pii interactions.",K Fujisaki 2015,2015,1 gene,Fujisaki-2015-Rice Exo70 interacts with a fung,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6410,PHI:4980,UniProt,G5A0G9,GenBank,EGZ11358,,,P6497,XEG1,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26163574,PubMed,10.1105/tpc.15.00390,Plant Cell. 2015 Jul;27(7):2057-72,wangyc@njau.edu.cn,"Glycoside hydrolase family 12 (GH12) protein, XEG1, exhibits xyloglucanase andb-glucanase activity.",Z Ma 2015,2015,1 gene,Ma-2015-A Phytophthora sojae Glycoside Hydrola,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6411,PHI:4980,UniProt,G5A0G9,GenBank,EGZ11358,,,P6497,XEG1,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26163574,PubMed,10.1105/tpc.15.00390,Plant Cell. 2015 Jul;27(7):2057-72,wangyc@njau.edu.cn,"Glycoside hydrolase family 12 (GH12) protein, XEG1, exhibits xyloglucanase andb-glucanase activity.",Z Ma 2015,2015,1 gene,Ma-2015-A Phytophthora sojae Glycoside Hydrola,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6412,PHI:4981,UniProt,D0Z7V7,GenBank,ACY84526,,,EIB202,mliC,,,,,,,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,52904,Scophthalmus maximus (related: turbot),,,,kidney; spleen,lysozyme inhibitor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25404031,PubMed,10.1128/IAI.02473-14,Infect Immun. 2015 Feb;83(2):583-90,lsun@qdio.ac.cn,"Compared to the ivyEt or mliCEt single knockout strains, the mliCEt ivyEt double-knockout strain was significantly impaired in most of the virulence features.",M Li 2014,2014,2 genes,Li-2014-Edwardsiella tarda MliC_ a lysozyme in,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6413,PHI:4982,UniProt,M0QAC7,GenBank,GAC65540,,,ATCC 15947,ivy,,,,,,,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,52904,Scophthalmus maximus (related: turbot),,,,kidney; spleen,lysozyme inhibitor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25404031,PubMed,10.1128/IAI.02473-14,Infect Immun. 2015 Feb;83(2):583-90,lsun@qdio.ac.cn,"Compared to the ivyEt or mliCEt single knockout strains, the mliCEt ivyEt double-knockout strain was significantly impaired in most of the virulence features.",M Li 2014,2014,2 genes,Li-2014-Edwardsiella tarda MliC_ a lysozyme in,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6414,PHI:4981,UniProt,D0Z7V7,GenBank,ACY84526,,,EIB202,mliC,,,,,,PHI:4982,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,52904,Scophthalmus maximus (related: turbot),,,,kidney; spleen,lysozyme inhibitor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25404031,PubMed,10.1128/IAI.02473-14,Infect Immun. 2015 Feb;83(2):583-90,lsun@qdio.ac.cn,"Compared to the ivyEt or mliCEt single knockout strains, the mliCEt ivyEt double-knockout strain was significantly impaired in most of the virulence features.",M Li 2014,2014,2 genes,Li-2014-Edwardsiella tarda MliC_ a lysozyme in,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6415,PHI:4982,UniProt,M0QAC7,GenBank,GAC65540,,,ATCC 15947,ivy,,,,,,PHI:4981,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,52904,Scophthalmus maximus (related: turbot),,,,kidney; spleen,lysozyme inhibitor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25404031,PubMed,10.1128/IAI.02473-14,Infect Immun. 2015 Feb;83(2):583-90,lsun@qdio.ac.cn,"Compared to the ivyEt or mliCEt single knockout strains, the mliCEt ivyEt double-knockout strain was significantly impaired in most of the virulence features.",M Li 2014,2014,2 genes,Li-2014-Edwardsiella tarda MliC_ a lysozyme in,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6416,PHI:4983,UniProt,Q87AW0,GenBank,AAO29541,,,Temecula1,PD1703,,,,,,,2371,Xylella fastidiosa,945689,EB92-1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Carignane,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26218423,PubMed,10.1371/journal.pone.0133796,PLoS One. 2015 Jul 28;10(7):e0133796,dgabr@ufl.edu,EB92-1/PD1703 transformants showed significantly increased disease symptoms on grapevines. Genes predicted to encode PD0928 (Zot) and a PD0986 (hemagglutinin) were also cloned into pBBR1MCS-5 and moved into EB92-1; both transformants also showed significantly increased symptoms on V.vinifera vines.,S Zhang 2015,2015,3 genes,Zhang-2015-Three New Pierce's Disease Pathogen,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6417,PHI:4984,UniProt,Q877P5,GenBank,AAO28780,,,Temecula1,PD0928,,,,,,,2371,Xylella fastidiosa,945689,EB92-1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Carignane,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26218423,PubMed,10.1371/journal.pone.0133796,PLoS One. 2015 Jul 28;10(7):e0133796,dgabr@ufl.edu,EB92-1/PD1703 transformants showed significantly increased disease symptoms on grapevines. Genes predicted to encode PD0928 (Zot) and a PD0986 (hemagglutinin) were also cloned into pBBR1MCS-5 and moved into EB92-1; both transformants also showed significantly increased symptoms on V.vinifera vines.,S Zhang 2015,2015,3 genes,Zhang-2015-Three New Pierce's Disease Pathogen,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6418,PHI:4985,UniProt,Q87CS7,GenBank,AAO28848,,,Temecula1,PD0986,,,,,,,2371,Xylella fastidiosa,945689,EB92-1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Carignane,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26218423,PubMed,10.1371/journal.pone.0133796,PLoS One. 2015 Jul 28;10(7):e0133796,dgabr@ufl.edu,EB92-1/PD1703 transformants showed significantly increased disease symptoms on grapevines. Genes predicted to encode PD0928 (Zot) and a PD0986 (hemagglutinin) were also cloned into pBBR1MCS-5 and moved into EB92-1; both transformants also showed significantly increased symptoms on V.vinifera vines.,S Zhang 2015,2015,3 genes,Zhang-2015-Three New Pierce's Disease Pathogen,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6419,PHI:4986,UniProt,G4Z7E0,GenBank,EGZ19648,,,P6497,Gcn5,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,histone acetyltransferases,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,RP,26209751,PubMed,10.1016/j.micpath.2015.07.015,Microb Pathog. 2015 Jul 23;87:51-58,rende7@126.com,"Mutants had normal development, but compared to wild type strains they had higher sensitivity to hydrogen peroxide (H2O2) and significantly reduced virulence in soybean.",W Zhao 2015,2015,1 gene,Zhao-2015-The histone acetyltransferase PsGcn5,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6420,PHI:4987,UniProt,P43077,GenBank,AAA34346,,,A72,HEX1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,beta-hexosaminidase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,26177944,PubMed,10.1002/mbo3.274,Microbiologyopen. 2015 Jul 14,asis_datta@rediffmail.com,Virulence study in the systemic mouse murine model showed thatDhex1strain is significantly less virulent in comparison to the wild-type strain.,D Ruhela 2015,2015,1 gene,Ruhela-2015-In vivo role of Candida albicans b,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6421,PHI:4988,UniProt,M2TW52,GenBank,EMD85941,,,C5,Ppt1,,,,,,,5016,Bipolaris maydis,665024,C4,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-N,,,leaf,sfp-type 4'-phosphopantetheinyl transferase,,,,reduced virulence,yes,,,,,reduced,,reduced; aberrant,,no,H2O2; 2DP,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26168137,PubMed,10.1094/MPMI-03-15-0068-R,Mol Plant Microbe Interact. 2015 Jul 13,ainizzati@upm.edu.my,The ppt1 strains of all species were also reduced in tolerance to oxidative stress and iron depletion. Cochliobolus heterostrophus is pathogen anamorph name,N A I M Zainudin 2015,2015,1 gene,"Mohd Zainudin-2015-Virulence, host selective t",BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6422,PHI:4989,UniProt,W6ZBM1,GenBank,EUC41146,,,ATCC 44560,Ppt1,,,,,,,101162,Bipolaris oryzae,930090,WK-1C,brown spot,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,sfp-type 4'-phosphopantetheinyl transferase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,H2O2; 2DP,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26168137,PubMed,10.1094/MPMI-03-15-0068-R,Mol Plant Microbe Interact. 2015 Jul 13,ainizzati@upm.edu.my,The ppt1 strains of all species were also reduced in tolerance to oxidative stress and iron depletion.,N A I M Zainudin 2015,2015,1 gene,"Mohd Zainudin-2015-Virulence, host selective t",BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6423,PHI:4990,UniProt,J5K8H0,GenBank,EJP70406,,,ARSEF 2860,ras3,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,Ras ATPases,,,high-osmolarity-glycerol (HOG) pathway,reduced virulence,,,,,,reduced,,increased,reduced,no,NaCl; menadione; H2O2; Congo red; carbendazim,"H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; congo red: CHEBI:34653; carbendazim: CHEBI:3392, CAS:10605-21-7",,,,,gene mutation; gene complementation,,,RP,26162967,PubMed,10.1016/j.fgb.2015.07.002,Fungal Genet Biol. 2015 Jul 7;82:85-94,mgfeng@zju.edu.cn,"Mutants show reduced thermotolerance and decreased UV-B resistance. Moreover, Dras3 was much more sensitive to the oxidative stress of menadione than of H2O2 and to the stress of high osmolarity than of cell wall perturbation during growth.",Y Guan 2015,2015,1 gene,Guan-2015-A novel Ras GTPase (Ras3) regulates,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6424,PHI:4991,UniProt,Q2G282,GenBank,ABD31053,,,NCTC 8325,PerR,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,hydrogen peroxide sensor,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26134568,PubMed,10.1074/jbc.M115.664961,J Biol Chem. 2015 Aug 14;290(33):20374-86,jwl@hanyang.ac.kr,S. aureus cells expressing PerR from Bacillus subtilis killed C. elegans more rapidly than did those expressing PerR Staphylococcus aureus.,C Ji 2015,2015,1 gene,Ji-2015-Staphylococcus aureus PerR is a Hypers,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6425,PHI:4992,UniProt,Q5A7M9,GenBank,EAK98758,,,SC5314,rhr2,,,,,,,5476,Candida albicans,,DAY185,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,liver; spleen; pancreas,phosphoglycerol phosphatase,,,,reduced virulence,,,yes,yes,,,,reduced,,no,,,,,,,gene mutation,,,RP,26213976,PubMed,10.3390/pathogens4030573,Pathogens. 2015 Jul 24;4(3):573-89,apm1@cmu.edu,"We report here that an rhr2delta/delta mutant is defective in infection of abdominal organs and persistence in abscesses . We find here that overexpression of ALS1 in the mutant restores infection of organs, but does not improve persistence in abscesses.",J V Desai 2015,2015,1 gene,Desai-2015-Coordination of Candida albicans In,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6426,PHI:4994,UniProt,A0A0E7TWI5,GenBank,CRD14017,,,K13_0827,glpQ2,,,,,,,1313,Streptococcus pneumoniae,,CGMH836,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),,,,lung,glycerophosphodiester phosphodiesterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,RP,25422269,PubMed,10.1128/IAI.02357-14,Infect Immun. 2015 Feb;83(2):682-92,ypchuang@ndmctsgh.edu.tw,"In a murine respiratory tract infection model,glpQ2was important for nasopharynx and lung colonization.",Y Chuang 2014,2014,1 gene,Chuang-2014-The impact of glpQ2 gene on virule,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6427,PHI:4995,UniProt,W0S3I8,GenBank,AKG27571,,,AP1,RocA,,,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,histidine kinas,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26192205,PubMed,10.1111/mmi.13136,Mol Microbiol. 2015 Jul 20,psumby@medicine.nevada.edu,,E W Miller,2015,1 gene,Miller-2015-Regulatory Rewiring Confers Seroty,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6428,PHI:4996,UniProt,B0VDE7,GenBank,WP_001985623,,,AYE,AbuO,,,,,,,470,Acinetobacter baumannii,509173,AYE,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,outer membrane protein,,,,reduced virulence,,,,,,,,reduced,,no,amikacin; carbenicillin; ceftriaxone; meropenem; streptomycin; tigecycline; benzalkonium chloride; chlorhexidine; H2O2; sodium nitroprusside; deoxycholate; sodium chloride; EtBr; acridine orange; acriflavine; rhodamine; safranin; ampicillin; triclosan,amikacin: CHEBI:2637; carbenicillin: CHEBI:3393; ceftriaxone: CHEBI:29007; meropenem: CHEBI:43968; streptomycin: CHEBI:17076; tigecycline: CHEBI:149836; benzalkonium chloride: CHEBI:3020; chlorhexidine: CHEBI:3614; H2O2: CHEBI:16240; sodium nitroprusside: CHEBI:29321; deoxycholate: CHEBI:23614; sodium chloride: CHEBI:26710; EtBr: CHEBI:4883; acridine orange: CHEBI:51739; acriflavine: CHEBI:74728; ampicillin: CHEBI:28971; triclosan: CHEBI:164200,,,,,gene disruption; gene complementation,,,RP,25512405,PubMed,10.1128/AAC.03626-14,Antimicrob Agents Chemother. 2015 Feb;59(2):1236-45,rmohan@imtech.res.in,"Inactivation ofabuO led to increased sensitivity to high osmolarity and oxidative stress challenge. The abuO mutant displayed increased susceptibility to antibiotics, such as amikacin, carbenicillin, ceftriaxone, meropenem, streptomycin, and tigecycline, and hospital-based disinfectants, such as benzalkonium chloride and chlorhexidine.",V B Srinivasan 2014,2014,1 gene,"Srinivasan-2014-AbuO, a TolC-like outer membra",BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6429,PHI:4997,,no data found,,,,,,Fgrab2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,Rab GTPases,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26177389,PubMed,10.1111/1462-2920.12982,Environ Microbiol. 2015 Jul 14,wangzh@fafu.edu.cn,,H Zheng 2015,2015,9 genes,Zheng-2015-Rab GTPases are essential for membr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6430,PHI:4998,,no data found,,,,,,Fgrab4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,Rab GTPases,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26177389,PubMed,10.1111/1462-2920.12982,Environ Microbiol. 2015 Jul 14,wangzh@fafu.edu.cn,,H Zheng 2015,2015,9 genes,Zheng-2015-Rab GTPases are essential for membr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6431,PHI:4999,,no data found,,,,,,Fgrab51,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,Rab GTPases,,,,loss of pathogenicity,,,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26177389,PubMed,10.1111/1462-2920.12982,Environ Microbiol. 2015 Jul 14,wangzh@fafu.edu.cn,,H Zheng 2015,2015,9 genes,Zheng-2015-Rab GTPases are essential for membr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6432,PHI:5000,,no data found,,,,,,Fgrab52,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,Rab GTPases,,,,loss of pathogenicity,,,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26177389,PubMed,10.1111/1462-2920.12982,Environ Microbiol. 2015 Jul 14,wangzh@fafu.edu.cn,,H Zheng 2015,2015,9 genes,Zheng-2015-Rab GTPases are essential for membr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6433,PHI:5001,,no data found,,,,,,Fgrab6,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,Rab GTPases,,,,loss of pathogenicity,,,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26177389,PubMed,10.1111/1462-2920.12982,Environ Microbiol. 2015 Jul 14,wangzh@fafu.edu.cn,,H Zheng 2015,2015,9 genes,Zheng-2015-Rab GTPases are essential for membr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6434,PHI:5002,,no data found,,,,,,Fgrab7,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,Rab GTPases,,,,loss of pathogenicity,,,,,,,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26177389,PubMed,10.1111/1462-2920.12982,Environ Microbiol. 2015 Jul 14,wangzh@fafu.edu.cn,,H Zheng 2015,2015,9 genes,Zheng-2015-Rab GTPases are essential for membr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6435,PHI:5003,,no data found,,,,,,Fgrab8,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,Rab GTPases,,,,loss of pathogenicity,,,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26177389,PubMed,10.1111/1462-2920.12982,Environ Microbiol. 2015 Jul 14,wangzh@fafu.edu.cn,,H Zheng 2015,2015,9 genes,Zheng-2015-Rab GTPases are essential for membr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6436,PHI:5004,,no data found,,,,,,FgyptA,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,Rab GTPases,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26177389,PubMed,10.1111/1462-2920.12982,Environ Microbiol. 2015 Jul 14,wangzh@fafu.edu.cn,,H Zheng 2015,2015,9 genes,Zheng-2015-Rab GTPases are essential for membr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6437,PHI:5005,,no data found,,,,,,FgrabX,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,Rab GTPases,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26177389,PubMed,10.1111/1462-2920.12982,Environ Microbiol. 2015 Jul 14,wangzh@fafu.edu.cn,,H Zheng 2015,2015,9 genes,Zheng-2015-Rab GTPases are essential for membr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6438,PHI:5006,UniProt,Q2VEB5,GenBank,ABB52003,,,UT888,sua,,,,,,,1349,Streptococcus uberis,,UT888,mastitis,even-toed ungulates,9913,Bos taurus (related: cattle),Holstein Friesian,,,mammary gland,adhesion molecule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26216456,PubMed,10.1016/j.vetmic.2015.07.005,Vet Microbiol. 2015 Sep 30;179(3-4):332-5,ralmeida@utk.edu,,R A Almeida 2015,2015,1 gene,Almeida-2015-Role of Streptococcus uberis adhe,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6439,PHI:5007,,no data found,GenBank,ABK66296,,,104,MBP-1,,,,MAV_4504; MAV_0623,"MAV_4504, UniProt: A0A0H2ZZK7; MAV_0623, UniProt: A0A0H2ZYN4",,1764,Mycobacterium avium,439334,subsp. hominissuis strain 104,respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,microaggregate binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: antibody inhibition assay,,,RP,25422262,PubMed,10.1128/IAI.02699-14,Infect Immun. 2015 Feb;83(2):625-36,luiz.bermudez@oregonstate.edu,MBP-1 immune serum significantly inhibited M. Avium subsp. Hominissuis infection throughout the respiratory tracts of mice.,L Babrak 2014,2014,1 gene,Babrak-2014-The Environment of Mycobacterium a,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6440,PHI:5008,,no data found,,,,,,AirSR,,,,,,,1280,Staphylococcus aureus,,WCUH29,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,the AirSR system positively regulates the expression of the sspABC operon at the transcriptional level and additional secreted virulence factors.,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26191060,PubMed,10.3389/fmicb.2015.00682,Front Microbiol. 2015 Jul 3;6:682,jixxx002@umn.edu,"Depletion of AirSR by antisense RNA expression or deletion of the genes, results in significant decrease in bacterial survival in human blood. Conversely, overexpression of AirR significantly promotes survival of S. aureusin blood.",J W Hall 2015,2015,1 gene,Hall-2015-The AirSR two-component system contr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6441,PHI:5008,,no data found,,,,,,AirSR,,,,,,,1280,Staphylococcus aureus,,WCUH29,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,the AirSR system positively regulates the expression of the sspABC operon at the transcriptional level and additional secreted virulence factors.,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26191060,PubMed,10.3389/fmicb.2015.00682,Front Microbiol. 2015 Jul 3;6:682,jixxx002@umn.edu,"Depletion of AirSR by antisense RNA expression or deletion of the genes, results in significant decrease in bacterial survival in human blood. Conversely, overexpression of AirR significantly promotes survival of S. aureusin blood.",J W Hall 2015,2015,1 gene,Hall-2015-The AirSR two-component system contr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6442,PHI:5008,,no data found,,,,,,AirSR,,,,,,,1280,Staphylococcus aureus,,WCUH29,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,the AirSR system positively regulates the expression of the sspABC operon at the transcriptional level and additional secreted virulence factors.,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26191060,PubMed,10.3389/fmicb.2015.00682,Front Microbiol. 2015 Jul 3;6:682,jixxx002@umn.edu,"Depletion of AirSR by antisense RNA expression or deletion of the genes, results in significant decrease in bacterial survival in human blood. Conversely, overexpression of AirR significantly promotes survival of S. aureusin blood.",J W Hall 2015,2015,1 gene,Hall-2015-The AirSR two-component system contr,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6443,PHI:5009,UniProt,Q8Z111,GenBank,CAD06944,,,CT18,T4519,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,secreted eukaryote-like serine/threonine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25404028,PubMed,10.1128/IAI.02521-14,Infect Immun. 2015 Feb;83(2):522-33,dasss@icmr.org.in,The role of T4519 in the pathogenesis ofSalmonellaTyphi is underscored by the significantly decreased mortality of mice infected with the Ty2 t4519strain and the fact that the competitive index of this strain for causing systemic infection is 0.25% that of the wild-type strain.,N Theeya 2014,2014,1 gene,Theeya-2014-An Inducible and Secreted Eukaryot,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6444,PHI:5010,UniProt,P18177,GenBank,CAA37298,,,VPI 10463,TcdB,,,,,,,1496,Clostridioides difficile,,,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25404023,PubMed,10.1128/IAI.02316-14,Infect Immun. 2015 Feb;83(2):502-13,hfeng@umaryland.edu,"Consistent with these in vitro results, a cysteine protease noncleavable mutant, TcdB-L543A, delayed toxicity in mice, whereas glycosyltransferase-deficient TcdB demonstrated no toxicity up to 500-fold of the 50% lethal dose (LD50) when it was injected systemically. Pathogen formerly called Clostridium difficile",S Li 2014,2014,1 gene,Li-2014-Critical Roles of Clostridium difficil,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6445,PHI:5011,UniProt,A0A0E3X1L1,GenBank,AKB90684,,,Wp1,RpA,,,,,,,329,Ralstonia pickettii,,WP1,pseudobacteremia; asymptomatic colonization,primates,9606,Homo sapiens (related: human),Hep-G2 cell line; HeLa cell line,,,Hep-G2 cell; HeLa cell; Vero cell,extracellular protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26184602,PubMed,10.1111/jam.12903,J Appl Microbiol. 2015 Jul 15,ltwu@mail.cmu.edu.tw,"RpA, an extracellular protease similar to the metalloprotease of serralysin family, is required for pathogenicity of Ralstonia pickettii",C Chen 2015,2015,1 gene,"Chen-2015-RpA, an extracellular protease simil",BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6446,PHI:5012,UniProt,Q2YRP4,GenBank,CAJ11473,,,2308,vtlR,chromosome 1,,,abcR2; bab1_0914; bab2_0512; bab2_0574,"bab1_0914, UniProt: Q2YNL6; bab2_0512, UniProt: Q2YKY2; bab2_0574, UniProt: Q2YKS4",,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,LysR-family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26175079,PubMed,10.1111/mmi.13123,Mol Microbiol. 2015 Jul 15,caswellc@vt.edu,B. abortus bab1_1517mutant strain was significantly attenuated in macrophages and mice.,L M Sheehan 2015,2015,1 gene,Sheehan-2015-A LysR-family transcriptional reg,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6447,PHI:5013,UniProt,A0A0H3B439,GenBank,ACA68428,,,YPIII,znuB,,,,,,PHI:5014,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,zinc transporter,,,,reduced virulence,,,,,,,,,,no,H2O2; CdCl2; diamide; gentamicin,H2O2: CHEBI:16240; CdCl2: CHEBI:35456; gentamicin: CHEBI:17833,,,,,gene mutation; gene complementation,,,RP,26134274,PubMed,10.1371/journal.ppat.1005020,PLoS Pathog. 2015 Jul 2;11(7):e1005020,xihuishen@nwsuaf.edu.cn,Disruption of the classic zinc transporter ZnuABC together with T6SS-4 or yezP results in mutants that almost completely lost virulence against mice,T Wang 2015,2015,3 genes,Wang-2015-Type VI Secretion System Transports,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6448,PHI:5014,UniProt,A0A0H3B7J5,GenBank,ACA69816,,,YPIII,yezP,,,,,,PHI:5013,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,Zn2+ binding protein substrate,,,,reduced virulence,,,,,,,,,,no,H2O2; CdCl2; diamide; gentamicin,H2O2: CHEBI:16240; CdCl2: CHEBI:35456; gentamicin: CHEBI:17833,,,,,gene mutation; gene complementation,,,RP,26134274,PubMed,10.1371/journal.ppat.1005020,PLoS Pathog. 2015 Jul 2;11(7):e1005020,xihuishen@nwsuaf.edu.cn,Disruption of the classic zinc transporter ZnuABC together with T6SS-4 or yezP results in mutants that almost completely lost virulence against mice,T Wang 2015,2015,3 genes,Wang-2015-Type VI Secretion System Transports,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6449,PHI:5015,UniProt,A0A0B6PSU3,GenBank,AJJ71876,,,1,T6SS-4,,,,,,PHI:5013,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,type VI secretion system,,,,reduced virulence,,,,,,,,,,no,H2O2; CdCl2; diamide; gentamicin,H2O2: CHEBI:16240; CdCl2: CHEBI:35456; gentamicin: CHEBI:17833,,,,,gene mutation; gene complementation,,,RP,26134274,PubMed,10.1371/journal.ppat.1005020,PLoS Pathog. 2015 Jul 2;11(7):e1005020,xihuishen@nwsuaf.edu.cn,Disruption of the classic zinc transporter ZnuABC together with T6SS-4 or yezP results in mutants that almost completely lost virulence against mice,T Wang 2015,2015,3 genes,Wang-2015-Type VI Secretion System Transports,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6450,PHI:5013,UniProt,A0A0H3B439,GenBank,ACA68428,,,YPIII,znuB,,,,,,PHI:5015,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,zinc transporter,,,,reduced virulence,,,,,,,,,,no,H2O2; CdCl2; diamide; gentamicin,H2O2: CHEBI:16240; CdCl2: CHEBI:35456; gentamicin: CHEBI:17833,,,,,gene mutation; gene complementation,,,RP,26134274,PubMed,10.1371/journal.ppat.1005020,PLoS Pathog. 2015 Jul 2;11(7):e1005020,xihuishen@nwsuaf.edu.cn,Disruption of the classic zinc transporter ZnuABC together with T6SS-4 or yezP results in mutants that almost completely lost virulence against mice,T Wang 2015,2015,3 genes,Wang-2015-Type VI Secretion System Transports,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6451,PHI:5016,UniProt,G4ZAY8,GenBank,EGZ20616,,,P6497,Psimpa1,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Hefeng 47,,,hypocotyl,importin alpha subunit,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,RP,26159511,PubMed,10.1016/j.fgb.2015.04.023,Fungal Genet Biol. 2015 Jul 6;82:108-115,wangyc@njau.edu.cn,"Silenced mutants Psimpa1 had a decreased growth rate, an aberrant mycelial morphology, and a severely impaired ability to form oospores and sporangia. In addition, the Psimpa1 mutants exhibited reduced pathogenicity compared to the wild type.",X Yang 2015,2015,1 gene,Yang-2015-The importin alpha subunit PsIMPA1 m,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6452,PHI:5017,UniProt,G4MVK9,GenBank,EHA54118,,,70-15,MoPEX11A,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Pex11 family members in peroxisomal division and pathogenicity,,,,reduced virulence,,yes,yes,,,,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26218097,PubMed,10.1371/journal.pone.0134249,PLoS One. 2015 Jul 28;10(7):e0134249,sungc01@sina.com,"MoPEX11A mutant exhibited typical peroxisome related defects, delayedconidial germination and appressoria formation, and decreased appressorial turgor and host penetration. As a result, the virulence ofMoPEX11Amutant was greatly reduced.",J Wang 2015,2015,3 genes,Wang-2015-One of Three Pex11 Family Members Is,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6453,PHI:5018,UniProt,G4NB22,GenBank,EHA48784,,,70-15,MoPEX11B,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Pex11 family members in peroxisomal division and pathogenicity,,,,unaffected pathogenicity,,no,no,,,,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26218097,PubMed,10.1371/journal.pone.0134249,PLoS One. 2015 Jul 28;10(7):e0134249,sungc01@sina.com,"MoPEX11A mutant exhibited typical peroxisome related defects, delayedconidial germination and appressoria formation, and decreased appressorial turgor and host penetration. As a result, the virulence ofMoPEX11Amutant was greatly reduced.",J Wang 2015,2015,3 genes,Wang-2015-One of Three Pex11 Family Members Is,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6454,PHI:5019,UniProt,G4N5N3,GenBank,EHA53023,,,70-15,MoPEX11C,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Pex11 family members in peroxisomal division and pathogenicity,,,,unaffected pathogenicity,,no,no,,,,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26218097,PubMed,10.1371/journal.pone.0134249,PLoS One. 2015 Jul 28;10(7):e0134249,sungc01@sina.com,"MoPEX11A mutant exhibited typical peroxisome related defects, delayedconidial germination and appressoria formation, and decreased appressorial turgor and host penetration. As a result, the virulence ofMoPEX11Amutant was greatly reduced.",J Wang 2015,2015,3 genes,Wang-2015-One of Three Pex11 Family Members Is,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6455,PHI:5017,UniProt,G4MVK9,GenBank,EHA54118,,,70-15,MoPEX11A,,,,,,PHI:5018,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Pex11 family members in peroxisomal division and pathogenicity,,,,reduced virulence,,yes,yes,,,,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26218097,PubMed,10.1371/journal.pone.0134249,PLoS One. 2015 Jul 28;10(7):e0134249,sungc01@sina.com,"MoPEX11A mutant exhibited typical peroxisome related defects, delayedconidial germination and appressoria formation, and decreased appressorial turgor and host penetration. As a result, the virulence ofMoPEX11Amutant was greatly reduced.",J Wang 2015,2015,3 genes,Wang-2015-One of Three Pex11 Family Members Is,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6456,PHI:5018,UniProt,G4NB22,GenBank,EHA48784,,,70-15,MoPEX11B,,,,,,PHI:5017,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Pex11 family members in peroxisomal division and pathogenicity,,,,reduced virulence,,yes,yes,,,,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26218097,PubMed,10.1371/journal.pone.0134249,PLoS One. 2015 Jul 28;10(7):e0134249,sungc01@sina.com,"MoPEX11A mutant exhibited typical peroxisome related defects, delayedconidial germination and appressoria formation, and decreased appressorial turgor and host penetration. As a result, the virulence ofMoPEX11Amutant was greatly reduced.",J Wang 2015,2015,3 genes,Wang-2015-One of Three Pex11 Family Members Is,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6457,PHI:5017,UniProt,G4MVK9,GenBank,EHA54118,,,70-15,MoPEX11A,,,,,,PHI:5019,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Pex11 family members in peroxisomal division and pathogenicity,,,,reduced virulence,,yes,yes,,,,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26218097,PubMed,10.1371/journal.pone.0134249,PLoS One. 2015 Jul 28;10(7):e0134249,sungc01@sina.com,"MoPEX11A mutant exhibited typical peroxisome related defects, delayedconidial germination and appressoria formation, and decreased appressorial turgor and host penetration. As a result, the virulence ofMoPEX11Amutant was greatly reduced.",J Wang 2015,2015,3 genes,Wang-2015-One of Three Pex11 Family Members Is,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6458,PHI:5019,UniProt,G4N5N3,GenBank,EHA53023,,,70-15,MoPEX11C,,,,,,PHI:5017,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Pex11 family members in peroxisomal division and pathogenicity,,,,reduced virulence,,yes,yes,,,,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26218097,PubMed,10.1371/journal.pone.0134249,PLoS One. 2015 Jul 28;10(7):e0134249,sungc01@sina.com,"MoPEX11A mutant exhibited typical peroxisome related defects, delayedconidial germination and appressoria formation, and decreased appressorial turgor and host penetration. As a result, the virulence ofMoPEX11Amutant was greatly reduced.",J Wang 2015,2015,3 genes,Wang-2015-One of Three Pex11 Family Members Is,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6459,PHI:5017,UniProt,G4MVK9,GenBank,EHA54118,,,70-15,MoPEX11A,,,,,,PHI:5019; PHI:5018,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Pex11 family members in peroxisomal division and pathogenicity,,,,reduced virulence,,yes,yes,,,,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26218097,PubMed,10.1371/journal.pone.0134249,PLoS One. 2015 Jul 28;10(7):e0134249,sungc01@sina.com,"MoPEX11A mutant exhibited typical peroxisome related defects, delayedconidial germination and appressoria formation, and decreased appressorial turgor and host penetration. As a result, the virulence ofMoPEX11Amutant was greatly reduced.",J Wang 2015,2015,3 genes,Wang-2015-One of Three Pex11 Family Members Is,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6460,PHI:5018,UniProt,G4NB22,GenBank,EHA48784,,,70-15,MoPEX11B,,,,,,PHI:5019; PHI:5017,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Pex11 family members in peroxisomal division and pathogenicity,,,,reduced virulence,,yes,yes,,,,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26218097,PubMed,10.1371/journal.pone.0134249,PLoS One. 2015 Jul 28;10(7):e0134249,sungc01@sina.com,"MoPEX11A mutant exhibited typical peroxisome related defects, delayedconidial germination and appressoria formation, and decreased appressorial turgor and host penetration. As a result, the virulence ofMoPEX11Amutant was greatly reduced.",J Wang 2015,2015,3 genes,Wang-2015-One of Three Pex11 Family Members Is,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6461,PHI:5019,UniProt,G4N5N3,GenBank,EHA53023,,,70-15,MoPEX11C,,,,,,PHI:5018; PHI:5017,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Pex11 family members in peroxisomal division and pathogenicity,,,,reduced virulence,,yes,yes,,,,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26218097,PubMed,10.1371/journal.pone.0134249,PLoS One. 2015 Jul 28;10(7):e0134249,sungc01@sina.com,"MoPEX11A mutant exhibited typical peroxisome related defects, delayedconidial germination and appressoria formation, and decreased appressorial turgor and host penetration. As a result, the virulence ofMoPEX11Amutant was greatly reduced.",J Wang 2015,2015,3 genes,Wang-2015-One of Three Pex11 Family Members Is,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6462,PHI:5020,UniProt,B1MGX0,GenBank,CAM60654,,,ATCC 19977,PLC,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536,pulmonary infection; cutaneo-mucous infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; liver,phospholipase C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25486995,PubMed,10.1128/IAI.02032-14,Infect Immun. 2015 Feb;83(2):780-91,fabienne.girard-misguich@uvsq.fr,Aerosol challenge of mice with M. Abscessus strains that were precultured in amoebae enhanced M. abscessuslung infectivity relative to M. Abscessus grown in broth culture.,J C B N'Goma 2014,2014,1 gene,Bakala N' Goma-2014-Mycobacterium abscessus Ph,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6463,PHI:5020,UniProt,B1MGX0,GenBank,CAM60654,,,ATCC 19977,PLC,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536,pulmonary infection; cutaneo-mucous infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,phospholipase C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25486995,PubMed,10.1128/IAI.02032-14,Infect Immun. 2015 Feb;83(2):780-91,fabienne.girard-misguich@uvsq.fr,M. Abscessus PLC knockout mutant that loss of PLC activity is deleterious toM. abscessusintracellular survival in amoebae.,J C B N'Goma 2014,2014,1 gene,Bakala N' Goma-2014-Mycobacterium abscessus Ph,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6464,PHI:5021,UniProt,P41783,GenBank,AAB60188,,,ATCC 14028s,prgH,,prgH::kan,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,bugs,74068,Macrosteles quadrilineatus (related: aster leafhopper),,,,alimentary canal,pathogenicity island-1 (SPI-1),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26150468,PubMed,10.1128/AEM.01464-15,Appl Environ Microbiol. 2015 Sep 15;81(18):6345-54,jeri.barak@wisc.edu,"prgH mutant, lacking a functional SPI-1, was recovered at significantly lower levels than wild-type (WT) in insect-homogenates at 24 h post-AAP, and complementation with prgH restored S. enterica persistence in M. quadrilineatus.",J P Dundore-Arias 2015,2015,2 genes,Dundore-Arias-2015-Persistence of ingested Sal,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6465,PHI:5022,UniProt,P74853,GenBank,CAA70533,,,LT2,ssaK,,ssaK::kan,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,bugs,74068,Macrosteles quadrilineatus (related: aster leafhopper),,,,alimentary canal,SPI-2 type III secretion systems (T3SS),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26150468,PubMed,10.1128/AEM.01464-15,Appl Environ Microbiol. 2015 Sep 15;81(18):6345-54,jeri.barak@wisc.edu,"No differences were observed between WT and an ssaK mutant, lacking a functional SPI-2, in insect-homogenates or between WT and either mutant in insect excretions.",J P Dundore-Arias 2015,2015,2 genes,Dundore-Arias-2015-Persistence of ingested Sal,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6466,PHI:5025,UniProt,Q0GYW4,GenBank,WP_039371444,,,,BceD,,,,,,,488447,Burkholderia contaminans,,IST408,cystic fibrosis,primates,9606,Homo sapiens (related: human),CFBE41o- cell line,,,lung epithelium cell line,tyrosine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,resistance,,gene mutation; gene complementation,,,RP,25486990,PubMed,10.1128/IAI.02713-14,Infect Immun. 2015 Feb;83(2):812-21,lmoreira@tecnico.ulisboa.pt,,A S Ferreira 2014,2014,2 genes,Ferreira-2014-The tyrosine kinase BceF and the,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6467,PHI:5026,UniProt,Q0GYW2,GenBank,WP_039355754,,,,BceF,,,,,,,488447,Burkholderia contaminans,,IST408,cystic fibrosis,primates,9606,Homo sapiens (related: human),CFBE41o- cell line,,,lung epithelium cell line,tyrosine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,susceptibility,,gene mutation; gene complementation,,,RP,25486990,PubMed,10.1128/IAI.02713-14,Infect Immun. 2015 Feb;83(2):812-21,lmoreira@tecnico.ulisboa.pt,,A S Ferreira 2014,2014,2 genes,Ferreira-2014-The tyrosine kinase BceF and the,BATCH_051,2015-08-01,MC,,,,,,,,,,,,,
,,Record 6468,PHI:5027,,no data found,GenBank,JZ350031,,,CT-21,ClToxB,,,,,,,1585795,Colletotrichum lentis,,CT-21,anthracnose,eudicots,3864,Lens culinaris (related: lentil),cv. Eston,,,stem; leaf,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26296655,PubMed,10.1186/s12864-015-1836-2,BMC Genomics. 2015 Aug 22;16(1):628,sabine.banniza@usask.ca,,V Bhadauria 2015,2015,1 gene,Bhadauria-2015-Candidate effectors contribute,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6469,PHI:5028,UniProt,I1RNH4,GenBank,ESU11528,,,PH-1,gta1,,,,,,,5518,Fusarium graminearum,,Fg 8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,GABA transaminases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26305050,PubMed,10.1111/mmi.13203,Mol Microbiol. 2015 Aug 25,joerg.bormann@uni-hamburg.de,Genetic disruption of the GABA shunt by deletion of two GABA transaminases renders the pathogen unable to utilize the plant stress metabolites GABA and putrescine. The mutants showed increased sensitivity against oxidative stress.,J Bönnighausen 2015,2015,2 genes,Bonnighausen-2015-Disruption of the GABA shunt,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6470,PHI:5029,UniProt,I1RRM1,GenBank,ESU12888,,,PH-1,gta2,,,,,,,5518,Fusarium graminearum,,Fg 8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,GABA transaminases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26305050,PubMed,10.1111/mmi.13203,Mol Microbiol. 2015 Aug 25,joerg.bormann@uni-hamburg.de,Genetic disruption of the GABA shunt by deletion of two GABA transaminases renders the pathogen unable to utilize the plant stress metabolites GABA and putrescine. The mutants showed increased sensitivity against oxidative stress.,J Bönnighausen 2015,2015,2 genes,Bonnighausen-2015-Disruption of the GABA shunt,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6471,PHI:5028,UniProt,I1RNH4,GenBank,ESU11528,,,PH-1,gta1,,,,,,PHI:5029,5518,Fusarium graminearum,,Fg 8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,GABA transaminases,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26305050,PubMed,10.1111/mmi.13203,Mol Microbiol. 2015 Aug 25,joerg.bormann@uni-hamburg.de,Genetic disruption of the GABA shunt by deletion of two GABA transaminases renders the pathogen unable to utilize the plant stress metabolites GABA and putrescine. The mutants showed increased sensitivity against oxidative stress.,J Bönnighausen 2015,2015,2 genes,Bonnighausen-2015-Disruption of the GABA shunt,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6472,PHI:5029,UniProt,I1RRM1,GenBank,ESU12888,,,PH-1,gta2,,,,,,PHI:5028,5518,Fusarium graminearum,,Fg 8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,GABA transaminases,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26305050,PubMed,10.1111/mmi.13203,Mol Microbiol. 2015 Aug 25,joerg.bormann@uni-hamburg.de,Genetic disruption of the GABA shunt by deletion of two GABA transaminases renders the pathogen unable to utilize the plant stress metabolites GABA and putrescine. The mutants showed increased sensitivity against oxidative stress.,J Bönnighausen 2015,2015,2 genes,Bonnighausen-2015-Disruption of the GABA shunt,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6473,PHI:5030,UniProt,Q88AL8,GenBank,AAO53915,,,DC3000,iaaL,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,indoleacetate-lysine ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26285820,PubMed,10.1186/s12866-015-0503-8,BMC Microbiol. 2015 Aug 19;15:165,crr@uma.es,Deletion of either the iaaL or the matE gene resulted in reduced fitness and virulence of Pto DC3000 in tomato plants.,M G Castillo-Lizardo 2015,2015,2 genes,Castillo-Lizard-2015-Contribution of the non-e,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6474,PHI:5031,UniProt,Q88AL9,GenBank,AAO53914,,,DC3000,matE,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,MATE (multidrug and toxic compound extrusion) family transporter gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26285820,PubMed,10.1186/s12866-015-0503-8,BMC Microbiol. 2015 Aug 19;15:165,crr@uma.es,Deletion of either the iaaL or the matE gene resulted in reduced fitness and virulence of Pto DC3000 in tomato plants.,M G Castillo-Lizardo 2015,2015,2 genes,Castillo-Lizard-2015-Contribution of the non-e,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6475,PHI:5032,,no data found,GenBank,ALC04448,,,,SCR96,,,,,,,29920,Phytophthora cactorum,,10300,root rot; collar rot; crown rot; foliar infection; fruit infection,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Maofen-802,,,leaf,SCR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing: gene complementation,,,RP,26307454,PubMed,10.1111/mpp.12303,Mol Plant Pathol. 2015 Aug 26,xrchen@yzu.edu.cn,Silencing of scr96 in P. cactorum resulted in that gene-silenced transformants lost their pathogenicity on host plants and were significantly more sensitive to oxidative stress. Transient expression of scr96partially recovered gene-silenced transformants'virulence on plants.,X Chen 2015,2015,1 gene,"Chen-2015-SCR96, a small cysteine-rich secreto",BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6476,PHI:5032,,no data found,GenBank,ALC04448,,,,SCR96,,,,,,,29920,Phytophthora cactorum,,10300,root rot; collar rot; crown rot; foliar infection; fruit infection,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun NN,,,leaf,SCR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing: gene complementation,,,RP,26307454,PubMed,10.1111/mpp.12303,Mol Plant Pathol. 2015 Aug 26,xrchen@yzu.edu.cn,Silencing of scr96 in P. cactorum resulted in that gene-silenced transformants lost their pathogenicity on host plants and were significantly more sensitive to oxidative stress. Transient expression of scr96partially recovered gene-silenced transformants'virulence on plants.,X Chen 2015,2015,1 gene,"Chen-2015-SCR96, a small cysteine-rich secreto",BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6477,PHI:5033,UniProt,G4NB40,GenBank,EHA48802,,,70-15,MoSRE1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,sterol regulatory element-binding protein,,,,unaffected pathogenicity,,yes,yes,yes,,increased,,wild type,wild type,no,CoCl2; methyl viologen; Congo red,CoCl2: CHEBI:35696; methyl viologen: CHEBI:28786; Congo red: CHEBI:34653,,,,,gene mutation,,,RP,26241858,PubMed,10.1371/journal.pone.0134939,PLoS One. 2015 Aug 4;10(8):e0134939,yonglee@snu.ac.kr,"The mutant for the sterol regulatory element-binding protein gene,MoSRE1, exhibited increased sensitivity to a hypoxia-mimicking agent, increased conidiation, and delayed invasive growth within host cells, which is suggestive of important roles in fungal development. However, such defects did not cause any significant decrease in disease severity. The other null mutant, for the alcohol dehydrogenase geneMoADH1, showed no defect in the hypoxiamimicking condition (using cobalt chloride) and fungal development.",J Choi 2015,2015,2 genes,Choi-2015-Genome-Wide Analysis of Hypoxia-Resp,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6478,PHI:5034,UniProt,G4NHC2,GenBank,EHA47632,,,70-15,MoADH1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,alcohol dehydrogenase,,,,unaffected pathogenicity,,no,no,no,,,,wild type,wild type,no,,,,,,,gene mutation,,,RP,26241858,PubMed,10.1371/journal.pone.0134939,PLoS One. 2015 Aug 4;10(8):e0134939,yonglee@snu.ac.kr,"The mutant for the sterol regulatory element-binding protein gene,MoSRE1, exhibited increased sensitivity to a hypoxia-mimicking agent, increased conidiation, and delayed invasive growth within host cells, which is suggestive of important roles in fungal development. However, such defects did not cause any significant decrease in disease severity. The other null mutant, for the alcohol dehydrogenase geneMoADH1, showed no defect in the hypoxiamimicking condition (using cobalt chloride) and fungal development.",J Choi 2015,2015,2 genes,Choi-2015-Genome-Wide Analysis of Hypoxia-Resp,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6479,PHI:5035,UniProt,Q4PGV2,GenBank,XP_756808,,,521,Hos2,chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,histone deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26317403,PubMed,10.1371/journal.ppat.1005134,PLoS Pathog. 2015 Aug 28;11(8):e1005134,joibecor@upo.es,,A Elías-Villalobos 2015,2015,2 genes,Elias-Villalobo-2015-The Hos2 Histone Deacetyl,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6480,PHI:5036,UniProt,Q4PCR1,GenBank,XP_758249,,,521,Clr3,chromosome 5,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,histone deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26317403,PubMed,10.1371/journal.ppat.1005134,PLoS Pathog. 2015 Aug 28;11(8):e1005134,joibecor@upo.es,,A Elías-Villalobos 2015,2015,2 genes,Elias-Villalobo-2015-The Hos2 Histone Deacetyl,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6481,PHI:5035,UniProt,Q4PGV2,GenBank,XP_756808,,,521,Hos2,chromosome 1,,,,,PHI:5036,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,histone deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26317403,PubMed,10.1371/journal.ppat.1005134,PLoS Pathog. 2015 Aug 28;11(8):e1005134,joibecor@upo.es,,A Elías-Villalobos 2015,2015,2 genes,Elias-Villalobo-2015-The Hos2 Histone Deacetyl,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6482,PHI:5036,UniProt,Q4PCR1,GenBank,XP_758249,,,521,Clr3,chromosome 5,,,,,PHI:5035,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,histone deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26317403,PubMed,10.1371/journal.ppat.1005134,PLoS Pathog. 2015 Aug 28;11(8):e1005134,joibecor@upo.es,,A Elías-Villalobos 2015,2015,2 genes,Elias-Villalobo-2015-The Hos2 Histone Deacetyl,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6483,PHI:5037,UniProt,J4UHQ6,GenBank,EJP62792,,,ARSEF 2860,OpS1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,PKS oosporein synthase 1,,,polyketide synthase (PKS) pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26305932,PubMed,10.1073/pnas.1503200112,Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11365-70,cswang@sibs.ac.cn,,P Feng 2015,2015,2 genes,Feng-2015-Fungal biosynthesis of the bibenzoqu,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6484,PHI:5038,UniProt,D1FVE6,GenBank,ACR78138,,,ARSEF 2860,OpS3,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,transcription factor regulates intrapathway gene expression,,,polyketide synthase (PKS) pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26305932,PubMed,10.1073/pnas.1503200112,Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11365-70,cswang@sibs.ac.cn,,P Feng 2015,2015,2 genes,Feng-2015-Fungal biosynthesis of the bibenzoqu,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6485,PHI:5039,UniProt,N4VRT7,GenBank,ENH83696,,,MAFF 240422,BUB2,,,,BFA1; Tem1,"BFA1, GenBank: ENH87866; Tem1, GenBank: ENH82693",,5465,Colletotrichum orbiculare,1213857,MAFF240422,anthracnose (cucumber),eudicots,3659,Cucumis sativus (related: cucumber),,,,cotyledon,two-component GAP consisting of Bub2 and Bfa1,,,,reduced virulence,,yes,,,,aberrant,,wild type,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,26320225,PubMed,10.1105/tpc.15.00179,Plant Cell. 2015 Aug 28. pii: tpc.15.00179,y_kubo@kpu.ac.jp,,F Fukada 2015,2015,2 genes,Fukada-2015-Colletotrichum orbiculare Regulate,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6486,PHI:5040,UniProt,N4W395,GenBank,ENH87866,,,MAFF 240422,BFA1,,,,BUB2; Tem1,"BUB2, GenBank: ENH83696; Tem1, GenBank: ENH82693",,5465,Colletotrichum orbiculare,1213857,MAFF240422,anthracnose (cucumber),eudicots,3659,Cucumis sativus (related: cucumber),,,,cotyledon,two-component GAP consisting of Bub2 and Bfa1,,,,reduced virulence,,yes,,,,aberrant,,wild type,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,26320225,PubMed,10.1105/tpc.15.00179,Plant Cell. 2015 Aug 28. pii: tpc.15.00179,y_kubo@kpu.ac.jp,,F Fukada 2015,2015,2 genes,Fukada-2015-Colletotrichum orbiculare Regulate,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6487,PHI:5041,UniProt,G4N7J5,GenBank,EHA50852,,,70-15,MoYAK1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,protein kinase,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced; aberrant,reduced,no,,,,,,,gene disruption; gene complementation,,,RP,26248223,PubMed,10.1111/1462-2920.13010,Environ Microbiol. 2015 Aug 6,kims@kangwon.ac.kr,,J Han 2015,2015,1 gene,Han-2015-Role of the MoYAK1 protein kinase gen,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6488,PHI:5042,UniProt,Q9X4G0,GenBank,AE004627_5,,,PAO1,hmgA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,homogentisate 1-2-dioxygenase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26252386,PubMed,10.1371/journal.pone.0134229,PLoS One. 2015 Aug 7;10(8):e0134229,jim.manos@sydney.edu.au,,C J Harmer 2015,2015,1 gene,Harmer-2015-Homogentisate 1-2-Dioxygenase Down,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6489,PHI:5042,UniProt,Q9X4G0,GenBank,AE004627_5,,,PAO1,hmgA,,,,,,,287,Pseudomonas aeruginosa,652611,AES-1M,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,homogentisate 1-2-dioxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26252386,PubMed,10.1371/journal.pone.0134229,PLoS One. 2015 Aug 7;10(8):e0134229,jim.manos@sydney.edu.au,,C J Harmer 2015,2015,1 gene,Harmer-2015-Homogentisate 1-2-Dioxygenase Down,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6490,PHI:5042,UniProt,Q9X4G0,GenBank,AE004627_5,,,PAO1,hmgA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,larva,homogentisate 1-2-dioxygenase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26252386,PubMed,10.1371/journal.pone.0134229,PLoS One. 2015 Aug 7;10(8):e0134229,jim.manos@sydney.edu.au,,C J Harmer 2015,2015,1 gene,Harmer-2015-Homogentisate 1-2-Dioxygenase Down,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6491,PHI:5042,UniProt,Q9X4G0,GenBank,AE004627_5,,,PAO1,hmgA,,,,,,,287,Pseudomonas aeruginosa,652611,AES-1M,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,larva,homogentisate 1-2-dioxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26252386,PubMed,10.1371/journal.pone.0134229,PLoS One. 2015 Aug 7;10(8):e0134229,jim.manos@sydney.edu.au,,C J Harmer 2015,2015,1 gene,Harmer-2015-Homogentisate 1-2-Dioxygenase Down,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6492,PHI:5043,UniProt,E7Q5D7,GenBank,EGA58194,,,FostersB,Hsp150p,,,,,,,4932,Saccharomyces cerevisiae,559292,S288c,,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,hear shock protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,calcofluor white (CFW); Congo red (CR),calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653,,,,,altered gene expression / gene regulation: overexpression,,,RP,26270963,PubMed,10.1371/journal.pone.0135174,PLoS One. 2015 Aug 13;10(8):e0135174,ywchang364@ntu.edu.tw,Overexpression of Hsp150p in lab strain increased cell wall integrity and potentially enhanced the virulence of yeast.,P Hsu 2015,2015,1 gene,Hsu-2015-Characterization of Cell Wall Protein,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6493,PHI:5044,UniProt,B0LX67,GenBank,ABY85194,,,,cna1,,,,,,,176275,Beauveria bassiana,,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,calcineurin,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); NaCl; sorbitol,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26319315,PubMed,10.1016/j.fgb.2015.08.009,Fungal Genet Biol. 2015 Aug 28;83:78-91,yjzhang@swu.edu.cn,"Gene knockouts of either the calcineurin CNA1 subunit or the Slt2 MAP kinase resulted in decreased tolerance to calcofluor white and high temperature. In contrast, theDcna1strain was more tolerant to Congo red but more sensitive to osmotic stress (NaCl, sorbitol) than the wild type, whereas theDslt2strain had the opposite phenotype.",S Huang 2015,2015,2 genes,Huang-2015-Interplay between calcineurin and t,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6494,PHI:5045,UniProt,G9DDS6,GenBank,AEU60018,,,Bb0062,slt2,,,,,,,176275,Beauveria bassiana,,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAP kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); NaCl; sorbitol,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26319315,PubMed,10.1016/j.fgb.2015.08.009,Fungal Genet Biol. 2015 Aug 28;83:78-91,yjzhang@swu.edu.cn,"Gene knockouts of either the calcineurin CNA1 subunit or the Slt2 MAP kinase resulted in decreased tolerance to calcofluor white and high temperature. In contrast, theDcna1strain was more tolerant to Congo red but more sensitive to osmotic stress (NaCl, sorbitol) than the wild type, whereas theDslt2strain had the opposite phenotype.",S Huang 2015,2015,2 genes,Huang-2015-Interplay between calcineurin and t,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6495,PHI:5046,UniProt,O42720,GenBank,AAC39354,,,G186AR,Cbp1,,G217B ura5delta cbp1::T-DNA (mutant 172-C5),,,,,5037,Histoplasma capsulatum,,G217B ura5Δ,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,calcium-binding protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,26288377,PubMed,10.1111/mmi.13168,Mol Microbiol. 2015 Aug 19,sil@cgl.ucsf.edu,,D T Isaac 2015,2015,1 gene,Isaac-2015-Macrophage cell death and transcrip,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6496,PHI:5047,UniProt,G4N572,GenBank,EHA52129,,,70-15,MoFis1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitochondrial fission protein,,,,reduced virulence,no,no,,,"the mutant lesions were non-proliferating, and were less coalesced as compared to the highly coalesced and proliferating lesions resulting from infection with the wild-type strain.",reduced,wild type,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26302847,PubMed,10.1016/j.micres.2015.06.002,Microbiol Res. 2015 Sep;178:51-8,jplu@zju.edu.cn,,I A Khan 2015,2015,1 gene,Khan-2015-Mitochondrial fission protein MoFis1,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6497,PHI:5048,UniProt,F8UNP0,GenBank,AEI75280,,,,Avr3b,,Avr3b cloned into pGBKT7,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean) (non-host bioassay: yeast),,,,leaf,nudix hydrolase,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,GmCYP1 (Cyclophilin with Peptidyl-prolyl cis-trans isomerase 1 (PPIase) activity cloned into pGADT7,UniProt: Q8W171; GenBank: AF456323_1,interacts in yeast two-hybrid,,other evidence: yeast two-hybrid,,,RP; AC,26317500,PubMed,10.1371/journal.ppat.1005139,PLoS Pathog. 2015 Aug 28;11(8):e1005139,wangyc@njau.edu.cn,Phytophthora sojaeRXLR effector Avr3b acts as a Nudix hydrolase when expressedin planta; and this enzymatic activity is required for full virulence of P.sojae strain P6497 in soybean (Glycine max).,G Kong 2015,2015,2 genes,Kong-2015-The Activation of Phytophthora Effec,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6498,PHI:5048,UniProt,F8UNP0,GenBank,AEI75280,,,,Avr3b,,"GST-Avr3b, pGEX4T-2, expressed in E.coli B21",,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean) (non-host bioassay: e. coli),,,,leaf,nudix hydrolase,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,"His-GmCYP1, pET28a, expressed in E.coli BL21",UniProt: Q8W171; GenBank: AF456323_1,positive co-IP,,other evidence: in vitro gst pull-down assay,,,RP; AC,26317500,PubMed,10.1371/journal.ppat.1005139,PLoS Pathog. 2015 Aug 28;11(8):e1005139,wangyc@njau.edu.cn,Phytophthora sojaeRXLR effector Avr3b acts as a Nudix hydrolase when expressedin planta; and this enzymatic activity is required for full virulence of P.sojae strain P6497 in soybean (Glycine max).,G Kong 2015,2015,2 genes,Kong-2015-The Activation of Phytophthora Effec,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6499,PHI:5048,UniProt,F8UNP0,GenBank,AEI75280,,,,Avr3b,,FLAG-Avr3b inserted into pGR107,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean) (non-host bioassay: n. benthamiana),,,,leaf,nudix hydrolase,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,GmCYP1 inserted into pBinGFP,UniProt: Q8W171; GenBank: AF456323_1,positive co-IP,,functional test in host: transient expression,co-expression in N. benthamiana leaves by agroinfiltration. IP using FLAG specific antibodies,,RP; AC,26317500,PubMed,10.1371/journal.ppat.1005139,PLoS Pathog. 2015 Aug 28;11(8):e1005139,wangyc@njau.edu.cn,Phytophthora sojaeRXLR effector Avr3b acts as a Nudix hydrolase when expressedin planta; and this enzymatic activity is required for full virulence of P.sojae strain P6497 in soybean (Glycine max).,G Kong 2015,2015,2 genes,Kong-2015-The Activation of Phytophthora Effec,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6500,PHI:5048,UniProt,F8UNP0,GenBank,AEI75280,,,,Avr3b,,Avr3bP132A,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean) (non-host bioassay: n. benthamiana),,,,leaf,nudix hydrolase,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,reduced disease,,functional test in host: transient expression,agroinfiltration Avr3bP132A,,RP; AC,26317500,PubMed,10.1371/journal.ppat.1005139,PLoS Pathog. 2015 Aug 28;11(8):e1005139,wangyc@njau.edu.cn,(challenge with P.capsici). P132A mutation results in loss of virulence. Phytophthora sojaeRXLR effector Avr3b acts as a Nudix hydrolase when expressedin planta; and this enzymatic activity is required for full virulence of P.sojae strain P6497 in soybean (Glycine max).,G Kong 2015,2015,2 genes,Kong-2015-The Activation of Phytophthora Effec,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6501,PHI:5048,UniProt,F8UNP0,GenBank,AEI75280,,,,Avr3b,,Avr3bP132A,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,Rps3b,,leaf,nudix hydrolase,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,no rps3b-mediated cell death,functional test in host: transient expression,bombardment with Avr3bP132A,,RP; AC,26317500,PubMed,10.1371/journal.ppat.1005139,PLoS Pathog. 2015 Aug 28;11(8):e1005139,wangyc@njau.edu.cn,P132A mutation results in loss of avirulence function (loss of recognition by Rps3b). Phytophthora sojaeRXLR effector Avr3b acts as a Nudix hydrolase when expressedin planta; and this enzymatic activity is required for full virulence of P.sojae strain P6497 in soybean (Glycine max).,G Kong 2015,2015,2 genes,Kong-2015-The Activation of Phytophthora Effec,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6502,PHI:5050,UniProt,Q59Z58,GenBank,XP_714771,,,SC5314,pst1,,(delta/delta/delta/delta)pst3-ycp4delta::HIS1/pst3-ycp4delta::LEU2 pst2delta::frt/pst2delta::frt pst1delta::frt/pst1delta::frt arg4delta/arg4delta,,,,PHI:5051; PHI:5052; PHI:5053,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,flavodoxin-like proteins,,,,loss of pathogenicity,,,,,,,,,,no,p-benzoquinone; menadione; napthoquinone; tert-butyl hydroperoxide; H2O2; linolenic acid; alpha-tocopherol,p-benzoquinone: CHEBI:39439; menadione: CHEBI:28869; napthoquinone: CHEBI:34055; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; linolenic acid: CHEBI:17351; alpha-tocopherol: CHEBI:18145,,,,,gene deletion: full; gene complementation,,,RP,26325183,PubMed,10.1371/journal.ppat.1005147,PLoS Pathog. 2015 Sep 1;11(9):e1005147,james.konopka@stonybrook.edu,"FLPs are critical for survival in the host, as the quadruple mutant was avirulent in a mouse model of systemic candidiasis under conditions where infection with wild type C. albicans was lethal. FLPs in bacteria and plants act as NAD(P)H quinone oxidoreductases, a C.albicans quadruple mutant lacking all four FLPs (pst1delta,pst2delta,pst3delta,ycp4delta) was more sensitive to benzoquinone.",L Li 2015,2015,4 genes,Li-2015-Flavodoxin-Like Proteins Protect Candi,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6503,PHI:5051,UniProt,Q59Y37,GenBank,XP_714456,,,SC5314,pst2,,(delta/delta/delta/delta)pst3-ycp4delta::HIS1/pst3-ycp4delta::LEU2 pst2delta::frt/pst2delta::frt pst1delta::frt/pst1delta::frt arg4delta/arg4delta,,,,PHI:5050; PHI:5052; PHI:5053,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,flavodoxin-like proteins,,,,loss of pathogenicity,,,,,,,,,,no,p-benzoquinone; menadione; napthoquinone; tert-butyl hydroperoxide; H2O2; linolenic acid; alpha-tocopherol,p-benzoquinone: CHEBI:39439; menadione: CHEBI:28869; napthoquinone: CHEBI:34055; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; linolenic acid: CHEBI:17351; alpha-tocopherol: CHEBI:18145,,,,,gene deletion: full; gene complementation,,,RP,26325183,PubMed,10.1371/journal.ppat.1005147,PLoS Pathog. 2015 Sep 1;11(9):e1005147,james.konopka@stonybrook.edu,"FLPs are critical for survival in the host, as the quadruple mutant was avirulent in a mouse model of systemic candidiasis under conditions where infection with wild type C. albicans was lethal. FLPs in bacteria and plants act as NAD(P)H quinone oxidoreductases, a C.albicans quadruple mutant lacking all four FLPs (pst1delta,pst2delta,pst3delta,ycp4delta) was more sensitive to benzoquinone.",L Li 2015,2015,4 genes,Li-2015-Flavodoxin-Like Proteins Protect Candi,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6504,PHI:5052,UniProt,Q59KV2,GenBank,XP_710366,,,SC5314,pst3,,(delta/delta/delta/delta)pst3-ycp4delta::HIS1/pst3-ycp4delta::LEU2 pst2delta::frt/pst2delta::frt pst1delta::frt/pst1delta::frt arg4delta/arg4delta,,,,PHI:5050; PHI:5051; PHI:5053,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,flavodoxin-like proteins,,,,loss of pathogenicity,,,,,,,,,,no,p-benzoquinone; menadione; napthoquinone; tert-butyl hydroperoxide; H2O2; linolenic acid; alpha-tocopherol,p-benzoquinone: CHEBI:39439; menadione: CHEBI:28869; napthoquinone: CHEBI:34055; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; linolenic acid: CHEBI:17351; alpha-tocopherol: CHEBI:18145,,,,,gene deletion: full; gene complementation,,,RP,26325183,PubMed,10.1371/journal.ppat.1005147,PLoS Pathog. 2015 Sep 1;11(9):e1005147,james.konopka@stonybrook.edu,"FLPs are critical for survival in the host, as the quadruple mutant was avirulent in a mouse model of systemic candidiasis under conditions where infection with wild type C. albicans was lethal. FLPs in bacteria and plants act as NAD(P)H quinone oxidoreductases, a C.albicans quadruple mutant lacking all four FLPs (pst1delta,pst2delta,pst3delta,ycp4delta) was more sensitive to benzoquinone.",L Li 2015,2015,4 genes,Li-2015-Flavodoxin-Like Proteins Protect Candi,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6505,PHI:5053,UniProt,Q59KV1,GenBank,XP_710367,,,SC5314,ycp4,,(delta/delta/delta/delta)pst3-ycp4delta::HIS1/pst3-ycp4delta::LEU2 pst2delta::frt/pst2delta::frt pst1delta::frt/pst1delta::frt arg4delta/arg4delta,,,,PHI:5050; PHI:5051; PHI:5052,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,flavodoxin-like proteins,,,,loss of pathogenicity,,,,,,,,,,no,p-benzoquinone; menadione; napthoquinone; tert-butyl hydroperoxide; H2O2; linolenic acid; alpha-tocopherol,p-benzoquinone: CHEBI:39439; menadione: CHEBI:28869; napthoquinone: CHEBI:34055; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; linolenic acid: CHEBI:17351; alpha-tocopherol: CHEBI:18145,,,,,gene deletion: full; gene complementation,,,RP,26325183,PubMed,10.1371/journal.ppat.1005147,PLoS Pathog. 2015 Sep 1;11(9):e1005147,james.konopka@stonybrook.edu,"FLPs are critical for survival in the host, as the quadruple mutant was avirulent in a mouse model of systemic candidiasis under conditions where infection with wild type C. albicans was lethal. FLPs in bacteria and plants act as NAD(P)H quinone oxidoreductases, a C.albicans quadruple mutant lacking all four FLPs (pst1delta,pst2delta,pst3delta,ycp4delta) was more sensitive to benzoquinone.",L Li 2015,2015,4 genes,Li-2015-Flavodoxin-Like Proteins Protect Candi,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6506,PHI:5052,UniProt,Q59KV2,GenBank,XP_710366,,,SC5314,pst3,,(pst3deltaycp4delta)pst3-ycp4delta::HIS1/pst3-ycp4delta::LEU2 arg4delta/arg4delta,,,,PHI:5053,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,flavodoxin-like proteins,,,,unaffected pathogenicity,,,,,,,,,,no,p-benzoquinone; menadione; napthoquinone; tert-butyl hydroperoxide; H2O2; linolenic acid; alpha-tocopherol,p-benzoquinone: CHEBI:39439; menadione: CHEBI:28869; napthoquinone: CHEBI:34055; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; linolenic acid: CHEBI:17351; alpha-tocopherol: CHEBI:18145,,,,,gene deletion: full; gene complementation,,,RP,26325183,PubMed,10.1371/journal.ppat.1005147,PLoS Pathog. 2015 Sep 1;11(9):e1005147,james.konopka@stonybrook.edu,"FLPs are critical for survival in the host, as the quadruple mutant was avirulent in a mouse model of systemic candidiasis under conditions where infection with wild type C. albicans was lethal. FLPs in bacteria and plants act as NAD(P)H quinone oxidoreductases, a C.albicans quadruple mutant lacking all four FLPs (pst1delta,pst2delta,pst3delta,ycp4delta) was more sensitive to benzoquinone.",L Li 2015,2015,4 genes,Li-2015-Flavodoxin-Like Proteins Protect Candi,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6507,PHI:5053,UniProt,Q59KV1,GenBank,XP_710367,,,SC5314,ycp4,,(pst3deltaycp4delta)pst3-ycp4delta::HIS1/pst3-ycp4delta::LEU2 arg4delta/arg4delta,,,,PHI:5052,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,flavodoxin-like proteins,,,,unaffected pathogenicity,,,,,,,,,,no,p-benzoquinone; menadione; napthoquinone; tert-butyl hydroperoxide; H2O2; linolenic acid; alpha-tocopherol,p-benzoquinone: CHEBI:39439; menadione: CHEBI:28869; napthoquinone: CHEBI:34055; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; linolenic acid: CHEBI:17351; alpha-tocopherol: CHEBI:18145,,,,,gene deletion: full; gene complementation,,,RP,26325183,PubMed,10.1371/journal.ppat.1005147,PLoS Pathog. 2015 Sep 1;11(9):e1005147,james.konopka@stonybrook.edu,"FLPs are critical for survival in the host, as the quadruple mutant was avirulent in a mouse model of systemic candidiasis under conditions where infection with wild type C. albicans was lethal. FLPs in bacteria and plants act as NAD(P)H quinone oxidoreductases, a C.albicans quadruple mutant lacking all four FLPs (pst1delta,pst2delta,pst3delta,ycp4delta) was more sensitive to benzoquinone.",L Li 2015,2015,4 genes,Li-2015-Flavodoxin-Like Proteins Protect Candi,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6508,PHI:5051,UniProt,Q59Y37,GenBank,XP_714456,,,SC5314,pst2,,(pst2deltapst3deltaycp4delta) pst3-ycp4delta::HIS1/pst3-ycp4delta::LEU2 pst2delta::frt/pst2delta::frt ARG4/arg4delta,,,,PHI:5052; PHI:5053,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,flavodoxin-like proteins,,,,loss of pathogenicity,,,,,,,,,,no,p-benzoquinone; menadione; napthoquinone; tert-butyl hydroperoxide; H2O2; linolenic acid; alpha-tocopherol,p-benzoquinone: CHEBI:39439; menadione: CHEBI:28869; napthoquinone: CHEBI:34055; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; linolenic acid: CHEBI:17351; alpha-tocopherol: CHEBI:18145,,,,,gene deletion: full; gene complementation,,,RP,26325183,PubMed,10.1371/journal.ppat.1005147,PLoS Pathog. 2015 Sep 1;11(9):e1005147,james.konopka@stonybrook.edu,"FLPs are critical for survival in the host, as the quadruple mutant was avirulent in a mouse model of systemic candidiasis under conditions where infection with wild type C. albicans was lethal. FLPs in bacteria and plants act as NAD(P)H quinone oxidoreductases, a C.albicans quadruple mutant lacking all four FLPs (pst1delta,pst2delta,pst3delta,ycp4delta) was more sensitive to benzoquinone.",L Li 2015,2015,4 genes,Li-2015-Flavodoxin-Like Proteins Protect Candi,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6509,PHI:5052,UniProt,Q59KV2,GenBank,XP_710366,,,SC5314,pst3,,(pst2deltapst3deltaycp4delta) pst3-ycp4delta::HIS1/pst3-ycp4delta::LEU2 pst2delta::frt/pst2delta::frt ARG4/arg4delta,,,,PHI:5051; PHI:5053,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,flavodoxin-like proteins,,,,loss of pathogenicity,,,,,,,,,,no,p-benzoquinone; menadione; napthoquinone; tert-butyl hydroperoxide; H2O2; linolenic acid; alpha-tocopherol,p-benzoquinone: CHEBI:39439; menadione: CHEBI:28869; napthoquinone: CHEBI:34055; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; linolenic acid: CHEBI:17351; alpha-tocopherol: CHEBI:18145,,,,,gene deletion: full; gene complementation,,,RP,26325183,PubMed,10.1371/journal.ppat.1005147,PLoS Pathog. 2015 Sep 1;11(9):e1005147,james.konopka@stonybrook.edu,"FLPs are critical for survival in the host, as the quadruple mutant was avirulent in a mouse model of systemic candidiasis under conditions where infection with wild type C. albicans was lethal. FLPs in bacteria and plants act as NAD(P)H quinone oxidoreductases, a C.albicans quadruple mutant lacking all four FLPs (pst1delta,pst2delta,pst3delta,ycp4delta) was more sensitive to benzoquinone.",L Li 2015,2015,4 genes,Li-2015-Flavodoxin-Like Proteins Protect Candi,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6510,PHI:5053,UniProt,Q59KV1,GenBank,XP_710367,,,SC5314,ycp4,,(pst2deltapst3deltaycp4delta) pst3-ycp4delta::HIS1/pst3-ycp4delta::LEU2 pst2delta::frt/pst2delta::frt ARG4/arg4delta,,,,PHI:5051; PHI:5052,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,flavodoxin-like proteins,,,,loss of pathogenicity,,,,,,,,,,no,p-benzoquinone; menadione; napthoquinone; tert-butyl hydroperoxide; H2O2; linolenic acid; alpha-tocopherol,p-benzoquinone: CHEBI:39439; menadione: CHEBI:28869; napthoquinone: CHEBI:34055; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; linolenic acid: CHEBI:17351; alpha-tocopherol: CHEBI:18145,,,,,gene deletion: full; gene complementation,,,RP,26325183,PubMed,10.1371/journal.ppat.1005147,PLoS Pathog. 2015 Sep 1;11(9):e1005147,james.konopka@stonybrook.edu,"FLPs are critical for survival in the host, as the quadruple mutant was avirulent in a mouse model of systemic candidiasis under conditions where infection with wild type C. albicans was lethal. FLPs in bacteria and plants act as NAD(P)H quinone oxidoreductases, a C.albicans quadruple mutant lacking all four FLPs (pst1delta,pst2delta,pst3delta,ycp4delta) was more sensitive to benzoquinone.",L Li 2015,2015,4 genes,Li-2015-Flavodoxin-Like Proteins Protect Candi,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6511,PHI:5054,UniProt,J5JPY5,GenBank,EJP64951,,,ARSEF 2860,wetA,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,developmental regulator,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,menadione; H2O2; SDS; Congo red; NaCl; carbendazim,"H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:267101; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; carbendazim: CHEBI:3392, CAS:10605-21-7",,,,,gene mutation; gene complementation,,,RP,26243054,PubMed,10.1007/s00253-015-6823-7,Appl Microbiol Biotechnol. 2015 Aug 5.,mgfeng@zju.edu.cn,"The conidia of deltawetA showed more defective features than those of deltavosA, including smaller size, lesser density, lower hydrophobicity, and impaired cell walls although intracellular trehalose content decreased more in the aging culture of deltavosA than of deltawetA. As a result, conidial sensitivity to cell wall perturbation was elevated in deltawetA but unaffected in deltavosA, which produced conidia more sensitive to the oxidant menadione and the wetheat stress at 45 °C.",F Li 2015,2015,2 genes,Li-2015-WetA and VosA are distinct regulators,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6512,PHI:5055,UniProt,J4KR13,GenBank,EJP70154,,,ARSEF 2860,vosA,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,velvet protein,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,menadione; H2O2; SDS; Congo red; NaCl; carbendazim,"H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:267101; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; carbendazim: CHEBI:3392, CAS:10605-21-7",,,,,gene mutation; gene complementation,,,RP,26243054,PubMed,10.1007/s00253-015-6823-7,Appl Microbiol Biotechnol. 2015 Aug 5.,mgfeng@zju.edu.cn,"The conidia of deltawetA showed more defective features than those of deltavosA, including smaller size, lesser density, lower hydrophobicity, and impaired cell walls although intracellular trehalose content decreased more in the aging culture of deltavosA than of deltawetA. As a result, conidial sensitivity to cell wall perturbation was elevated in deltawetA but unaffected in deltavosA, which produced conidia more sensitive to the oxidant menadione and the wetheat stress at 45 °C.",F Li 2015,2015,2 genes,Li-2015-WetA and VosA are distinct regulators,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6513,PHI:5056,UniProt,Q59QW5,GenBank,EAK92885,,,SC5314,Flo8,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,transcription factor,,,cAMP/PKA pathway,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation: characterised,,,RP,26302841,PubMed,10.1016/j.micres.2015.05.007,Microbiol Res. 2015 Sep;178:1-8,mjxiang123456@126.com,"G723R and T751D Flo8 mutants enhanced activation of the Flo8 C terminus, thereby promoting filamentous growth and increasing virulence.",J Liu 2015,2015,1 gene,Liu-2015-Mutations in the Flo8 transcription f,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6514,PHI:5057,UniProt,Q51508,GenBank,CAA57969,,,PAO1,pchA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,gastrointestinal tract,isochorismate pyruvate lyase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26313907,PubMed,10.1371/journal.ppat.1005129,PLoS Pathog. 2015 Aug 27;11(8):e1005129,andrew.koh@utsouthwestern.edu,Deletion of both P. aeruginosa pyochelin and pyoverdine genes attenuates P. aeruginosa virulence,E Lopez-Medina 2015,2015,3 genes,Lopez-Medina-2015-Candida albicans Inhibits Ps,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6515,PHI:5058,UniProt,Q51507,GenBank,CAA57968,,,PAO1,pchB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,gastrointestinal tract,isochorismate pyruvate lyase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26313907,PubMed,10.1371/journal.ppat.1005129,PLoS Pathog. 2015 Aug 27;11(8):e1005129,andrew.koh@utsouthwestern.edu,Deletion of both P. aeruginosa pyochelin and pyoverdine genes attenuates P. aeruginosa virulence,E Lopez-Medina 2015,2015,3 genes,Lopez-Medina-2015-Candida albicans Inhibits Ps,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6516,PHI:5059,UniProt,Q9I168,GenBank,AAG05801,,,PAO1,pvdH,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,gastrointestinal tract,"L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26313907,PubMed,10.1371/journal.ppat.1005129,PLoS Pathog. 2015 Aug 27;11(8):e1005129,andrew.koh@utsouthwestern.edu,Deletion of both P. aeruginosa pyochelin and pyoverdine genes attenuates P. aeruginosa virulence,E Lopez-Medina 2015,2015,3 genes,Lopez-Medina-2015-Candida albicans Inhibits Ps,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6517,PHI:5057,UniProt,Q51508,GenBank,CAA57969,,,PAO1,pchA,,,,,,PHI:5058; PHI:5059,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,gastrointestinal tract,isochorismate pyruvate lyase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26313907,PubMed,10.1371/journal.ppat.1005129,PLoS Pathog. 2015 Aug 27;11(8):e1005129,andrew.koh@utsouthwestern.edu,Deletion of both P. aeruginosa pyochelin and pyoverdine genes attenuates P. aeruginosa virulence,E Lopez-Medina 2015,2015,3 genes,Lopez-Medina-2015-Candida albicans Inhibits Ps,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6518,PHI:5058,UniProt,Q51507,GenBank,CAA57968,,,PAO1,pchB,,,,,,PHI:5057; PHI:5059,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,gastrointestinal tract,isochorismate pyruvate lyase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26313907,PubMed,10.1371/journal.ppat.1005129,PLoS Pathog. 2015 Aug 27;11(8):e1005129,andrew.koh@utsouthwestern.edu,Deletion of both P. aeruginosa pyochelin and pyoverdine genes attenuates P. aeruginosa virulence,E Lopez-Medina 2015,2015,3 genes,Lopez-Medina-2015-Candida albicans Inhibits Ps,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6519,PHI:5059,UniProt,Q9I168,GenBank,AAG05801,,,PAO1,pvdH,,,,,,PHI:5057; PHI:5058,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,gastrointestinal tract,"L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26313907,PubMed,10.1371/journal.ppat.1005129,PLoS Pathog. 2015 Aug 27;11(8):e1005129,andrew.koh@utsouthwestern.edu,Deletion of both P. aeruginosa pyochelin and pyoverdine genes attenuates P. aeruginosa virulence,E Lopez-Medina 2015,2015,3 genes,Lopez-Medina-2015-Candida albicans Inhibits Ps,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6520,PHI:5060,UniProt,W8SQH8,GenBank,AHM11030,,,13_1,hilA,,SM6ΔhilA::cat (The Cm fragment of pKD3 replace the SM6 hilA gene),,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain SM6,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,gastrointestinal tract,invasion protein regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,26267091,PubMed,10.1016/j.rvsc.2015.05.004,Res Vet Sci. 2015 Aug;101:63-8,siguo_liu@hvri.ac.cn,SM6ΔhilA showed significantly reduced ability to invade Caco-2 cells and decreased pathogenicity in chicks.,S Lv 2015,2015,1 gene,Lv-2015-Characteristics of invasion-reduced hi,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6521,PHI:5061,UniProt,Q9KUH3,GenBank,AAF93716,,,N16961,CsrA,,csrA::Tn5 (carboxy-terminal insertion mutant),,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,diarrhea,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,intestine,small RNA-binding protein involved in the regulation of a wide range of cellular processes.,,,,reduced virulence,,,,,,,,wild type,,yes,,,,,,,gene mutation,,,RP,26242626,PubMed,10.1128/mBio.01064-15,MBio. 2015 Aug 4;6(4):e01064,armey@austin.utexas.edu,"CsrA is likely essential in V. cholerae, since a complete deletion ofcsrAwas not possible; however, point mutations in CsrA were tolerated well. The CsrA Arg6His mutant had wild-type growth in vitro but was severely attenuated in the infant mouse model of V. cholerae infection, showing that CsrA is critical for pathogenesis.",A R Mey 2015,2015,1 gene,Mey-2015-Vibrio cholerae CsrA Regulates ToxR L,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6522,PHI:5062,UniProt,A0A0K0GI30,GenBank,ACD57755,,,PXO99A,DetR,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taipei309,,,leaf,A cytoplasmic signaling component of the TCS,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26315668,PubMed,10.1111/mpp.12305,Mol Plant Pathol. 2015 Aug 27,swlee6803@khu.ac.kr,,M Nguyen 20154,2015,1 gene,Nguyen-2015-Role of DetR in defense is critica,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6523,PHI:5063,UniProt,B4EY92,GenBank,CAR43305,,,HI4320,ppk,,,,,,,584,Proteus mirabilis,529507,HI4320,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bladder,polyphosphate kinase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene disruption; gene complementation,,,RP,26233310,PubMed,10.1007/s00430-015-0430-1,Med Microbiol Immunol. 2015 Aug 2,dxyzgy@163.com,"The ppk mutant was deficient in resistance to oxidative, hyperosmotic and heat stress.",L Peng 2015,2015,1 gene,Peng-2015-Involvement of polyphosphate kinase,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6524,PHI:5064,,no data found,GenBank,5C00_D,,,,MdbA,,,,,,,1717,Corynebacterium diphtheriae,,,diphtheria,rodents,10141,Cavia porcellus (related: domestic guinea pig),Hartley,,,,thiol-disulfide oxidoreductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,26294390,PubMed,10.1111/mmi.13172,Mol Microbiol. 2015 Aug 21,ton-that.hung@uth.tmc.edu,"Deletion of mdbA results in a severe temperature-sensitive cell division phenotype. This mutant also fails to assemble pilus structures and is greatly defective in toxin production. Consistent with these defects, the mdbAmutant is attenuated in a guinea pig model of diphtheritic toxemia.",M E Reardon-Robinson 2015,2015,1 gene,Reardon-Robinso-2015-A thiol-disulfide oxidore,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6525,PHI:5065,UniProt,Q4WVG0,GenBank,EAL91416,,,Af293,pkcA,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,protein kinase C; cell wall integrity,,,cell wall integrity (CWI) pathway,unaffected pathogenicity,,,,,,aberrant,,aberrant,,no,caspofungin; voriconazole; amphotericin B; Congo red (CR); calcofluor white (CFW); echinocandin; anidulafungin (AF); sodium dodecyl sulfate (SDS); nikkomycin Z (NKZ); fluconazole (FLUC); EDTA,"voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; amphotericin B: CHEBI:2682; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; echinocandin: CHEBI:57248; anidulafungin: CHEBI:55346; SDS: CHEBI:8984; nikkomycin Z: CHEBI:623918; fluconazole: CHEBI:46081, CAS:86386-73-4; EDTA: CHEBI:64758",,,,,gene mutation: characterised; gene complementation,,,RP,26295576,PubMed,10.1371/journal.pone.0135195,PLoS One. 2015 Aug 21;10(8):e0135195,imalavazi@ufscar.br,PkcAG579R is involved in the formation of proper conidial architecture and protection to oxidative damage. The pkcA G579R mutant elicits increased production of TNF-alphaand phagocytosis but it has no impact on virulence in a murine model of invasive pulmonary aspergillosis.,M C Rocha 2015,2015,1 gene,Rocha-2015-The Aspergillus fumigatus pkcAG579R,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6526,PHI:5066,UniProt,Q5GZN1,GenBank,AAW75840,,,KACC 10331,citB,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain IR42,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,response regulator,,,,reduced virulence,,,,,,aberrant,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,26250545,PubMed,10.1007/s11274-015-1914-2,World J Microbiol Biotechnol. 2015 Oct;31(10):1619-27,starighi@um.ac.ir,"The swarming motility, resistance to hydrogen peroxide, induced a hypersensitive response,in planta growth and pathogenicity were reduced in XooM176 mutant compared to that of wild-type.",M Sahebi 2015,2015,1 gene,Sahebi-2015-CitB is required for full virulenc,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6527,PHI:5067,UniProt,W9ZT25,GenBank,EXK24251,,,26406,AVRFOM2,,,,,,,5507,Fusarium oxysporum,1089452,f. sp. melonis strain 26406,wilt (melon),eudicots,3656,Cucumis melo (related: muskmelon),cv. Cha-T,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26305378,PubMed,10.1111/nph.13584,New Phytol. 2015 Aug 25,m.rep@uva.nl,"AVRFOM2, the gene that encodes the avirulence protein recognized by the melon Fom-2gene.",S M Schmidt 2015,2015,1 gene,Schmidt-2015-Comparative genomics of Fusarium,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6528,PHI:5068,UniProt,I1S2C4,GenBank,CEF86247,,,PH-1,MCC,chromosome 3,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,spike,encoding methylcrotonyl-CoA-carboxylase,,,branched-chain amino acid (BCAA) metabolic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26248604,PubMed,10.1111/mmi.13155,Mol Microbiol. 2015 Aug 6,rajagopal.subramaniam@agr.gc.ca,Disrupting the leucine metabolic pathway significantly reduced disease.,R Subramaniam 2015,2015,1 gene,Subramaniam-2015-Leucine metabolism regulates,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6529,PHI:5069,UniProt,Q9A0G6,GenBank,AAZ51220,,,MGAS5005,GacA,,,,,,,1314,Streptococcus pyogenes,,5448,infection,,,,Lethal pathogen phenotype,,,,dTDP-4-dehydrorhamnose reductas,,,,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,26278404,PubMed,10.1111/mmi.13169,Mol Microbiol. 2015 Aug 17,hczdorfmueller@dundee.ac.uk,Analysis of a saturated mutant GAS library using Tn-sequencing and generation of a conditionalexpression mutant identified gacAas an essential gene for GAS.,S L van der Beek 2015,2015,1 gene,van der Beek-2015-GacA is Essential for Group,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6530,PHI:5069,UniProt,Q9A0G6,GenBank,AAZ51220,,,MGAS5005,GacA,,,,,,,1314,Streptococcus pyogenes,471876,NZ131,infection,,,,Lethal pathogen phenotype,,,,dTDP-4-dehydrorhamnose reductas,,,,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,26278404,PubMed,10.1111/mmi.13169,Mol Microbiol. 2015 Aug 17,hczdorfmueller@dundee.ac.uk,Analysis of a saturated mutant GAS library using Tn-sequencing and generation of a conditionalexpression mutant identified gacAas an essential gene for GAS.,S L van der Beek 2015,2015,1 gene,van der Beek-2015-GacA is Essential for Group,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6531,PHI:5070,,no data found,GenBank,ALC76523,,,ss1-3,RipG7,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3880,Medicago truncatula (related: barrel medic),cv. A17,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,26300048,PubMed,10.1111/mpp.12302,Mol Plant Pathol. 2015 Aug 24,nemo.peeters@toulouse.inra.fr,"RipG7 interact with M. truncatula SKP1-like/MSKa protein, essential for the function of RipG7 in virulence.",K Wang 2015,2015,1 gene,Wang-2015-Functional Assignment to Positively,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6532,PHI:5071,UniProt,Q9KML4-Q9KML3,GenBank,AAF96231-AAF96232,,,N16961,relBE-1,chromosome 2,"lacZ-, 4vca0323vca0324derivative of C6706",,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,encoding functional toxins,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,26275048,PubMed,10.1371/journal.pone.0135696,PLoS One. 2015 Aug 14;10(8):e0135696,kanbiao@icdc.cn,"Deletion analyses of each relBE locus indicate that RelBE systems are involved in biofilm formation and reactive oxygen species (ROS) resistance. Interestingly, all sevenrelBE loci are induced under the standard virulence induction conditions and two of therelBE mutants displayed a colonization defect, which was not due to an effect on virulence gene expression.",Y Wang 2015,2015,1 gene,Wang-2015-Functional RelBE-Family Toxin-Antito,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6533,PHI:5072,UniProt,Q9KML3-Q9K3D4,GenBank,AAF96232-AAF96257,,,N16961,relBE-2,chromosome 2,"LacZ-, 4vca0348vca0349derivative of C6706",,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,encoding functional toxins,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26275048,PubMed,10.1371/journal.pone.0135696,PLoS One. 2015 Aug 14;10(8):e0135696,kanbiao@icdc.cn,"Deletion analyses of each relBE locus indicate that RelBE systems are involved in biofilm formation and reactive oxygen species (ROS) resistance. Interestingly, all sevenrelBE loci are induced under the standard virulence induction conditions and two of therelBE mutants displayed a colonization defect, which was not due to an effect on virulence gene expression.",Y Wang 2015,2015,1 gene,Wang-2015-Functional RelBE-Family Toxin-Antito,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6534,PHI:5073,UniProt,Q9KMD9-Q9KMD8,GenBank,AAF96328-AAF96329,,,N16961,relBE-3,chromosome 2,"lacZ-, 4vca0422vca0423derivative of C6706",,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,encoding functional toxins,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26275048,PubMed,10.1371/journal.pone.0135696,PLoS One. 2015 Aug 14;10(8):e0135696,kanbiao@icdc.cn,"Deletion analyses of each relBE locus indicate that RelBE systems are involved in biofilm formation and reactive oxygen species (ROS) resistance. Interestingly, all sevenrelBE loci are induced under the standard virulence induction conditions and two of therelBE mutants displayed a colonization defect, which was not due to an effect on virulence gene expression.",Y Wang 2015,2015,1 gene,Wang-2015-Functional RelBE-Family Toxin-Antito,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6535,PHI:5074,UniProt,H9L4R3-H9L4T4,GenBank,AAF96350-AAF96351,,,N16961,relBE-4,chromosome 2,"lacZ-, 4vca0444vca0445derivative of C6706",,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,encoding functional toxins,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,26275048,PubMed,10.1371/journal.pone.0135696,PLoS One. 2015 Aug 14;10(8):e0135696,kanbiao@icdc.cn,"Deletion analyses of each relBE locus indicate that RelBE systems are involved in biofilm formation and reactive oxygen species (ROS) resistance. Interestingly, all sevenrelBE loci are induced under the standard virulence induction conditions and two of therelBE mutants displayed a colonization defect, which was not due to an effect on virulence gene expression.",Y Wang 2015,2015,1 gene,Wang-2015-Functional RelBE-Family Toxin-Antito,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6536,PHI:5075,UniProt,Q9KMA1-Q9KMA0,GenBank,AAF96381-AAF96382,,,N16961,relBE-5,chromosome 2,"lacZ-, 4vca0477vca0478derivative of C6706",,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,encoding functional toxins,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26275048,PubMed,10.1371/journal.pone.0135696,PLoS One. 2015 Aug 14;10(8):e0135696,kanbiao@icdc.cn,"Deletion analyses of each relBE locus indicate that RelBE systems are involved in biofilm formation and reactive oxygen species (ROS) resistance. Interestingly, all sevenrelBE loci are induced under the standard virulence induction conditions and two of therelBE mutants displayed a colonization defect, which was not due to an effect on virulence gene expression.",Y Wang 2015,2015,1 gene,Wang-2015-Functional RelBE-Family Toxin-Antito,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6537,PHI:5076,UniProt,Q9KM93-Q9KM92,GenBank,AAF96392-AAF96393,,,N16961,relBE-6,chromosome 2,"lacZ-, 4vca0488vca0489derivative of C6706",,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,encoding functional toxins,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26275048,PubMed,10.1371/journal.pone.0135696,PLoS One. 2015 Aug 14;10(8):e0135696,kanbiao@icdc.cn,"Deletion analyses of each relBE locus indicate that RelBE systems are involved in biofilm formation and reactive oxygen species (ROS) resistance. Interestingly, all sevenrelBE loci are induced under the standard virulence induction conditions and two of therelBE mutants displayed a colonization defect, which was not due to an effect on virulence gene expression.",Y Wang 2015,2015,1 gene,Wang-2015-Functional RelBE-Family Toxin-Antito,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6538,PHI:5077,UniProt,Q9K2M8-Q9K3D4,GenBank,AAF96256-AAF96257,,,N16961,relBE-7,chromosome 2,"lacZ-, 4vca0503vca0504derivative of C6706",,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,intestine,encoding functional toxins,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,26275048,PubMed,10.1371/journal.pone.0135696,PLoS One. 2015 Aug 14;10(8):e0135696,kanbiao@icdc.cn,"Deletion analyses of each relBE locus indicate that RelBE systems are involved in biofilm formation and reactive oxygen species (ROS) resistance. Interestingly, all sevenrelBE loci are induced under the standard virulence induction conditions and two of therelBE mutants displayed a colonization defect, which was not due to an effect on virulence gene expression.",Y Wang 2015,2015,1 gene,Wang-2015-Functional RelBE-Family Toxin-Antito,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6539,PHI:5078,UniProt,G2WYW6,GenBank,EGY21768,,,VdLs.17,VdCrz1,,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,269719,Cotinus coggygria (related: smokebush),,,,leaf,transcriptional regulator,,,calcium signaling,reduced virulence,,,,,,,,aberrant,,no,SDS,sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26235044,PubMed,10.1016/j.fgb.2015.07.011,Fungal Genet Biol. 2015 Sep;82:201-12,chengmt@bjfu.edu.cn,"After targeted deletion of VdCrz1, microsclerotia formation and melanin accumulation were impaired. Furthermore, the DVdCrz1mutants were hypersensitive to high concentrations of Ca2+ and cell wall-perturbing agents, such as sodium dodecyl sulfate. The addition of Mg2+ to the medium restores the microsclerotia formation in DVdCrz1 mutants.",D Xiong 2015,2015,1 gene,Xiong-2015-VdCrz1 is involved in microscleroti,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6540,PHI:5079,UniProt,Q7BI20,GenBank,AF305600_1,,,B31 R7,lmp1,,,,chondroitin-6-sulfate,,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin; heart; joint; bladder,"pathogen evasion of hostacquired immune defences, thereby facilitating persistent infection",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26247174,PubMed,10.1111/cmi.12487,Cell Microbiol. 2015 Aug 6,upal@umd.edu,Phenotypic analysis of the Lmp1-deficient mutant engineered to produce Lmp1M on the microbial surface suggests that Lmp1M can independently support B.burgdorferi infectivity in murine hosts.,X Yang 2015,2015,1 gene,Yang-2015-Middle region of the Borrelia burgdo,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6541,PHI:5080,UniProt,R4NM08,GenBank,WP_002939010,,,TL13,yefM,,,,,,PHI:5081,1307,Streptococcus suis,568813,SC84,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; brain; heart; liver; spleen; lung; kidney,toxin-antitoxin system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26272287,PubMed,10.1038/srep13125,Sci Rep. 2015 Aug 14;5:13125,beiwc@mail.hzau.edu.cn,"In a murine infection model, deletion of the yefM-yoeB locus had no effect on the virulence of S. Suis serotype 2.",C Zheng 2015,2015,2 genes,Zheng-2015-Identification and characterization,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6542,PHI:5081,UniProt,R4NWH4,GenBank,WP_012775363,,,TL13,yoeB,,,,,,PHI:5080,1307,Streptococcus suis,568813,SC84,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; brain; heart; liver; spleen; lung; kidney,toxin-antitoxin system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26272287,PubMed,10.1038/srep13125,Sci Rep. 2015 Aug 14;5:13125,beiwc@mail.hzau.edu.cn,"In a murine infection model, deletion of the yefM-yoeB locus had no effect on the virulence of S. Suis serotype 2.",C Zheng 2015,2015,2 genes,Zheng-2015-Identification and characterization,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6543,PHI:5082,UniProt,G4MVC4,GenBank,EHA54946,,,70-15,MoAcat1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,acetyl-CoA acetyltransferas,,,mevalonate pathway,reduced virulence,,yes,yes,yes,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26318870,PubMed,10.1016/j.fgb.2015.08.008,Fungal Genet Biol. 2015 Oct;83:58-67,zonghuaw@163.com,,Z Zhong 2015,2015,2 genes,Zhong-2015-Two different subcellular-localized,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6544,PHI:5083,UniProt,G4N745,GenBank,EHA49958,,,70-15,MoAcat2,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,acetyl-CoA acetyltransferas,,,mevalonate pathway,reduced virulence,,yes,yes,yes,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26318870,PubMed,10.1016/j.fgb.2015.08.008,Fungal Genet Biol. 2015 Oct;83:58-67,zonghuaw@163.com,,Z Zhong 2015,2015,2 genes,Zhong-2015-Two different subcellular-localized,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6545,PHI:5082,UniProt,G4MVC4,GenBank,EHA54946,,,70-15,MoAcat1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Jinchang 1316,,,leaf,acetyl-CoA acetyltransferas,,,mevalonate pathway,reduced virulence,,yes,yes,yes,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26318870,PubMed,10.1016/j.fgb.2015.08.008,Fungal Genet Biol. 2015 Oct;83:58-67,zonghuaw@163.com,,Z Zhong 2015,2015,2 genes,Zhong-2015-Two different subcellular-localized,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6546,PHI:5083,UniProt,G4N745,GenBank,EHA49958,,,70-15,MoAcat2,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Jinchang 1316,,,leaf,acetyl-CoA acetyltransferas,,,mevalonate pathway,reduced virulence,,yes,yes,yes,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26318870,PubMed,10.1016/j.fgb.2015.08.008,Fungal Genet Biol. 2015 Oct;83:58-67,zonghuaw@163.com,,Z Zhong 2015,2015,2 genes,Zhong-2015-Two different subcellular-localized,BATCH_052,2015-09-01,MC,,,,,,,,,,,,,
,,Record 6547,PHI:5084,UniProt,B2FMX9,GenBank,SMLT_RS09600,,,K279a,fur,,,,,,,40324,Stenotrophomonas maltophilia,522373,K279a,nosocomial bacterial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,global regulator/ regulation of iron uptake,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,iron,iron: CHEBI:82664,,,,,gene mutation,,,RP,26388863,PubMed,10.3389/fmicb.2015.00926,Front Microbiol. 2015 Sep 4;6:926,beatriz.passerini@gmail.com,"Fur mutants produced higher amounts of biofilms than K279a and CLSM analysis demonstrated improved adherence and biofilm organization. Under iron restricted conditions, K279a produced biofilms with more biomass and enhanced thickness.",C A García 2015,2015,1 gene,Garcia-2015-Iron is a signal for Stenotrophomo,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6548,PHI:5085,UniProt,A5YTY8,GenBank,ABQ81647,,,P6497,Avr3a/5,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,stem,RXLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,21779316,PubMed,10.1371/journal.pone.0020172,PLoS One. 2011;6(7):e20172,mark.gijzen@agr.gc.ca,Over-expression of Avr3a/5 in a P. Sojae strain that is normally virulent on Rps3a and Rps5 results in avirulence to Rps3a and Rps5; whereas silencing of Avr3a/5 causes gain of virulence in a P. sojae strain that is normally avirulent on Rps3a and Rps5 soybean lines.,S Dong 2011,2011,1 gene,Dong-2011-Sequence variants of the Phytophthor,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6549,PHI:5085,UniProt,A5YTY8,GenBank,ABQ81647,,,P6497,Avr3a/5,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,stem,RXLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,21779316,PubMed,10.1371/journal.pone.0020172,PLoS One. 2011;6(7):e20172,mark.gijzen@agr.gc.ca,Over-expression of Avr3a/5 in a P. Sojae strain that is normally virulent on Rps3a and Rps5 results in avirulence to Rps3a and Rps5; whereas silencing of Avr3a/5 causes gain of virulence in a P. sojae strain that is normally avirulent on Rps3a and Rps5 soybean lines.,S Dong 2011,2011,1 gene,Dong-2011-Sequence variants of the Phytophthor,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6550,PHI:5086,UniProt,Q5FBD2,GenBank,ABK20316,,,YSSA15,LukF-PV,,,,,,PHI:5087,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Hsd:ND4,,,,leukotoxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26330208,PubMed,10.1038/ncomms9125,Nat Commun. 2015 Sep 2;6:8125,victor.torres@nyumc.org,"Using in vivo murine models of infection, we show that LukSF-PV negatively influencesS. Aureus virulence and colonization by inhibiting LukED.",P Yoong 2015,2015,2 genes,Yoong-2015-Counter inhibition between leukotox,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6551,PHI:5087,UniProt,B1Q017,GenBank,ACB12435,,,YSSA15,LukS-PV,,,,,,PHI:5086,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Hsd:ND4,,,,leukotoxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26330208,PubMed,10.1038/ncomms9125,Nat Commun. 2015 Sep 2;6:8125,victor.torres@nyumc.org,"Using in vivo murine models of infection, we show that LukSF-PV negatively influencesS. Aureus virulence and colonization by inhibiting LukED.",P Yoong 2015,2015,2 genes,Yoong-2015-Counter inhibition between leukotox,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6552,PHI:5088,UniProt,D0NDJ8,GenBank,EEY56155,,,T30-4,AVR2,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,leaf,RXLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence,Agrobacterium transient assay: VIGS 3 weeks after initial infiltration with the TRV constructs,,RP,22885736,PubMed,10.1105/tpc.112.099861,Plant Cell. 2012 Aug;24(8):3420-34. Epub 2012 Aug 10,sophien.kamoun@tsl.ac.uk,"BSU-LIKE PROTEIN1 (BSL1) is required for R2-mediated perception of AVR2 and resistance to P. infestans. AVR2 associates with BSL1 and mediates the interaction of BSL1 with R2 in planta, possibly through the formation of a ternary complex.",D G O Saunders 2012,2012,1 gene,Saunders-2012-Host protein BSL1 associates wit,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6553,PHI:5089,UniProt,Q7CJ94,GenBank,AE013766_1,,,KIM10+,RovM,,rovM gene (y1629) replaced by kanamycingene cassette,,,,,632,Yersinia pestis,,KIM6+,bubonic plague,fleas,163159,Xenopsylla cheopis (related: oriental rat flea),,,,,LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26348850,PubMed,10.1371/journal.pone.0137508,PLoS One. 2015 Sep 8;10(9):e0137508,viveka@vetmed.wsu.edu,"ThedeltarovM mutant strain was not affected in characteristic biofilm gut blockage, growth, or survival during single infection of fleas. Nonetheless, during a co-infection of fleas, the deltarovM mutant exhibited a significant competitive fitness defect relative to the wild type strain.",V Vadyvaloo 2015,2015,1 gene,Vadyvaloo-2015-A LysR-Type Transcriptional Reg,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6554,PHI:5090,UniProt,R9RIP9,GenBank,AGM48625,,,M2,tssM,,tssM gene with the apramycin resistance cassette,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T6SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26401654,PubMed,10.1371/journal.pone.0138265,PLoS One. 2015 Sep 24;10(9):e0138265,suzana.salcedo@ibcp.fr,T6SS of DSM30011 is required for host colonization of the model organism Galleria mellonella suggesting that this system could play an important role in A. baumannii virulence in a strain-specific manner.,G D Repizo 2015,2015,1 gene,Repizo-2015-Differential Role of the T6SS in A,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6555,PHI:5091,UniProt,I1RD24,GenBank,ESU06835,,,PH-1,FgRic8,,,,FgGpa1; FgGpa3,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 33,,,spike,plays important roles in regulating G-protein signaling,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26341536,PubMed,10.1016/j.fgb.2015.08.012,Fungal Genet Biol. 2015 Oct;83:92-102,zhywang@zju.edu.cn,"Targeted gene deletion mutants of FgRIC8 exhibited a significant reduction in vegetative growth, conidiation, pigment production as well as deoxynivalenol (DON) biosynthesis. Pathogenicity assays using a point-inoculated spikelet approach showed that the mutants were severely impaired in virulence on flowering wheat heads.",J Wu 2015,2015,1 gene,Wu-2015-FgRIC8 is involved in regulating veget,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6556,PHI:5092,UniProt,D0C777,GenBank,EEX04842,,,ATCC 19606,PLD1,,,,,,PHI:5093; PHI:5094,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,phospholipases D,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,26379240,PubMed,10.1371/journal.pone.0138360,PLoS One. 2015 Sep 17;10(9):e0138360,averhoff@bio.uni-frankfurt.de,Galleria mellonella infection studies as well as invasion experiments using A549 human lung epithelial cells revealed that the three PLDs act in a concerted manner as virulence factors and are playing an important role in host cell invasion.,J Stahl 2015,2015,3 genes,Stahl-2015-Acinetobacter baumannii Virulence I,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6557,PHI:5093,UniProt,D0CG26,GenBank,EEX01694,,,ATCC 19606,PLD2,,,,,,PHI:5092; PHI:5094,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,phospholipases D,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,26379240,PubMed,10.1371/journal.pone.0138360,PLoS One. 2015 Sep 17;10(9):e0138360,averhoff@bio.uni-frankfurt.de,Galleria mellonella infection studies as well as invasion experiments using A549 human lung epithelial cells revealed that the three PLDs act in a concerted manner as virulence factors and are playing an important role in host cell invasion.,J Stahl 2015,2015,3 genes,Stahl-2015-Acinetobacter baumannii Virulence I,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6558,PHI:5094,UniProt,D0CDA1,GenBank,EEX02540,,,ATCC 19606,PLD3,,,,,,PHI:5092; PHI:5093,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,phospholipases D,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,RP,26379240,PubMed,10.1371/journal.pone.0138360,PLoS One. 2015 Sep 17;10(9):e0138360,averhoff@bio.uni-frankfurt.de,Galleria mellonella infection studies as well as invasion experiments using A549 human lung epithelial cells revealed that the three PLDs act in a concerted manner as virulence factors and are playing an important role in host cell invasion.,J Stahl 2015,2015,3 genes,Stahl-2015-Acinetobacter baumannii Virulence I,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6559,PHI:5095,,no data found,,,,,PG1,bgaI1,chromosome 2,,,,,,337,Burkholderia glumae,595500,PG1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Baldo,,,leaf,autoinducer-1 synthases,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,26362987,PubMed,10.1128/AEM.01043-15,Appl Environ Microbiol. 2015 Sep 11. pii: AEM.01043-15,wolfgang.streit@uni-hamburg.de,"Knockouts in each of these bgaI genes resulted in strongly decreased motility, reduced extracellular lipase activity, reduced ability to cause plant tissue maceration and decreased pathogenicity.",R Gao 2015,2015,3 genes,Gao-2015-Genome-wide RNA sequencing analysis o,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6560,PHI:5096,,no data found,,,,,PG1,bgaI2,chromosome 2,,,,,,337,Burkholderia glumae,595500,PG1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Baldo,,,leaf,autoinducer-1 synthases,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,26362987,PubMed,10.1128/AEM.01043-15,Appl Environ Microbiol. 2015 Sep 11. pii: AEM.01043-15,wolfgang.streit@uni-hamburg.de,"Knockouts in each of these bgaI genes resulted in strongly decreased motility, reduced extracellular lipase activity, reduced ability to cause plant tissue maceration and decreased pathogenicity.",R Gao 2015,2015,3 genes,Gao-2015-Genome-wide RNA sequencing analysis o,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6561,PHI:5097,,no data found,,,,,PG1,bgaI3,chromosome 1,,,,,,337,Burkholderia glumae,595500,PG1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Baldo,,,leaf,autoinducer-1 synthases,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,26362987,PubMed,10.1128/AEM.01043-15,Appl Environ Microbiol. 2015 Sep 11. pii: AEM.01043-15,wolfgang.streit@uni-hamburg.de,"Knockouts in each of these bgaI genes resulted in strongly decreased motility, reduced extracellular lipase activity, reduced ability to cause plant tissue maceration and decreased pathogenicity.",R Gao 2015,2015,3 genes,Gao-2015-Genome-wide RNA sequencing analysis o,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6562,PHI:5098,UniProt,B1NNT7,GenBank,ABV66276,,,T30-4,PiAvr4,,,,,,,4787,Phytophthora infestans,403677,T30-4,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),Cebeco44-31-5 line,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,18842095,PubMed,10.1094/MPMI-21-11-1460,Mol Plant Microbe Interact. 2008 Nov;21(11):1460-70,Francine.Govers@wur.n,"PiAvr4 encodes a 287-amino-acidprotein that belongs to a superfamily of effectors sharing the putative host-cell-targeting motif RXLR-dEER. Transformation of P. infestans race 4 strains with PiAvr4 resulted in transformants that were avirulent on R4 potato plants, demonstrating that PiAvr4is responsible for eliciting R4-mediated resistance.",P M J A van Poppel 2008,2008,1 gene,van Poppel-2008-The Phytophthora infestans avi,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6563,PHI:5099,UniProt,Q8NKX1,GenBank,AAL98667,,,MGAS8232,hasA,,,,,,,1314,Streptococcus pyogenes,301451,serotype M18,infection,rodents,10090,Mus musculus (related: house mouse),FVB/N,,,thigh muscle; spleen; liver; deep inguinal lymph node,hyaluronan capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26352587,PubMed,10.1371/journal.ppat.1005137,PLoS Pathog. 2015 Sep 9;11(9):e1005137,s.sriskandan@imperial.ac.uk,"The hyaluronan capsule of group A streptococci is a crucial virulence determinant for lymphatic tropism. The lymphatic vessel endothelial receptor-1 as the critical host receptor for capsular hyaluronan in the lymphatic system. Interference with this interactionin vivo impeded bacterial dissemination to local draining lymph nodes and, in the case of a hyper-encapsulated M18 strain, redirected streptococcal entry into the blood circulation, suggesting a pivotal role in the manifestation of streptococcal infections.",N N Lynskey 2015,2015,1 gene,Lynskey-2015-Rapid Lymphatic Dissemination of,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6564,PHI:5099,UniProt,Q8NKX1,GenBank,AAL98667,,,MGAS8232,hasA,,,,,,,1314,Streptococcus pyogenes,410076,serotype M89,infection,rodents,10090,Mus musculus (related: house mouse),FVB/N,,,thigh muscle; spleen; liver; deep inguinal lymph node,hyaluronan capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26352587,PubMed,10.1371/journal.ppat.1005137,PLoS Pathog. 2015 Sep 9;11(9):e1005137,s.sriskandan@imperial.ac.uk,"The hyaluronan capsule of group A streptococci is a crucial virulence determinant for lymphatic tropism. The lymphatic vessel endothelial receptor-1 as the critical host receptor for capsular hyaluronan in the lymphatic system. Interference with this interactionin vivo impeded bacterial dissemination to local draining lymph nodes and, in the case of a hyper-encapsulated M18 strain, redirected streptococcal entry into the blood circulation, suggesting a pivotal role in the manifestation of streptococcal infections.",N N Lynskey 2015,2015,1 gene,Lynskey-2015-Rapid Lymphatic Dissemination of,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6565,PHI:5100,,no data found,GenBank,WP_015961827,,,,MavN,,,,,,,446,Legionella pneumophila,272624,Philadelphia-1 Lp02,Legionnaires' disease; pneumonia,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,iron-regulated gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26330609,PubMed,10.1073/pnas.1511389112,Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):E5208-17,ralph.isberg@tufts.edu,,D T Isaac 2015,2015,1 gene,Isaac-2015-MavN is a Legionella pneumophila va,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6566,PHI:5101,UniProt,A7L812,GenBank,ABS50087,,,,Avr4/6,,,,,,,67593,Phytophthora sojae,,P7076,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,20192830,PubMed,10.1094/MPMI-23-4-0425,Mol Plant Microbe Interact. 2010 Apr;23(4):425-35,bmtyler@vt.edu,Different domains of Phytophthora sojae Effector Avr4/6 are recognized by soybean resistance genes Rps4 and Rps6,D Dou 2010,2010,1 gene,Dou-2010-Different domains of Phytophthora soj,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6567,PHI:5101,UniProt,A7L812,GenBank,ABS50087,,,,Avr4/6,,,,,,,67593,Phytophthora sojae,,P7076,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,20192830,PubMed,10.1094/MPMI-23-4-0425,Mol Plant Microbe Interact. 2010 Apr;23(4):425-35,bmtyler@vt.edu,Different domains of Phytophthora sojae Effector Avr4/6 are recognized by soybean resistance genes Rps4 and Rps6,D Dou 2010,2010,1 gene,Dou-2010-Different domains of Phytophthora soj,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6568,PHI:5102,UniProt,O51216,GenBank,AAC66590,,,B31,RelBbu,,,,,,,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,ear; talus; bladder,bifunctional enzyme responsible for both (p)ppGpp synthesis and hydrolysis,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26371761,PubMed,10.1371/journal.ppat.1005160,PLoS Pathog. 2015 Sep 15;11(9):e1005160,dan.drecktrah@mso.umt.edu,,D Drecktrah 2015,2015,1 gene,Drecktrah-2015-The Borrelia burgdorferi RelA_S,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6569,PHI:5102,UniProt,O51216,GenBank,AAC66590,,,B31,RelBbu,,,,,,,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),C3H/HeJ,,,larva,bifunctional enzyme responsible for both (p)ppGpp synthesis and hydrolysis,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26371761,PubMed,10.1371/journal.ppat.1005160,PLoS Pathog. 2015 Sep 15;11(9):e1005160,dan.drecktrah@mso.umt.edu,,D Drecktrah 2015,2015,1 gene,Drecktrah-2015-The Borrelia burgdorferi RelA_S,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6570,PHI:5103,UniProt,A0A0D5ZBN4,GenBank,AKA43766,,,3012,hacpl2,,,,,,,13563,Heterobasidion annosum,1264691,3012,root rot (conifer); butt rot (conifer),seed plants,3349,Pinus sylvestris (related: scots pine),,,,root,cerato-platanin-like protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,functional test in host: dipping,,,RP,26385823,PubMed,10.1016/j.fgb.2015.09.007,Fungal Genet Biol. 2015 Sep 15;84:41-51,hongxin.chen@helsinki.fi,,H Chen 2015,2015,1 gene,Chen-2015-A cerato-platanin-like protein HaCPL,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6571,PHI:5103,UniProt,A0A0D5ZBN4,GenBank,AKA43766,,,3012,hacpl2,,,,,,,13563,Heterobasidion annosum,1264691,3012,root rot (conifer); butt rot (conifer),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,cerato-platanin-like protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,functional test in host: dipping,,,RP,26385823,PubMed,10.1016/j.fgb.2015.09.007,Fungal Genet Biol. 2015 Sep 15;84:41-51,hongxin.chen@helsinki.fi,,H Chen 2015,2015,1 gene,Chen-2015-A cerato-platanin-like protein HaCPL,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6572,PHI:5104,UniProt,M2TGT8,GenBank,EMD67942,,,ND90Pr,VosA,,,,,,,45130,Bipolaris sorokiniana,665912,ND90Pr,common root rot (barley); spot blotch (barley); blackpoint (barley); common root rot (wheat); spot blotch (wheat); blackpoint (wheat),monocots,4513,Hordeum vulgare (related: barley),cv. Bowman,,,leaf,regulatory gene,,,,reduced virulence,,,,,mutants lesion size 68% of the wild type lesion size,increased; aberrant,,,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,26399184,PubMed,10.1016/j.funbio.2015.06.009,Fungal Biol. 2015 Oct;119(10):884-900,shaobin.zhong@ndsu.edu,,R WANG 2015,2015,1 gene,Wang-2015-The regulatory gene VosA affects con,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6573,PHI:5105,UniProt,D0N0I4,GenBank,EEY67147,,,T30-4,Avrblb2,,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,RXLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25894205,PubMed,10.1094/MPMI-12-14-0393-R,Mol Plant Microbe Interact. 2015 Aug;28(8):901-12,sophien.kamoun@tsl.ac.uk,,R F Oliva 2015,2015,1 gene,Oliva-2015-A Recent Expansion of the RXLR Effe,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6574,PHI:5106,UniProt,A4LAA7,GenBank,ABO48503,,,P6497,Avr1c,,,,,,,67593,Phytophthora sojae,,P7076,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,transient expression vector pFF19,,RP,24586999,PubMed,10.1371/journal.pone.0089738,PLoS One. 2014 Feb 24;9(2):e89738,mark.gijzen@agr.gc.ca,"Transient expression ofAvr1c or Avr1a triggers cell death on Rps1c plants, but Avr1c does not trigger cell death on Rps1a plants.",R Na 2014,2014,2 genes,Na-2014-Genome re-sequencing and functional an,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6575,PHI:5107,UniProt,A4L9T6,GenBank,ABO47652,,,P6497,Avr1a,,,,,,,67593,Phytophthora sojae,,P7076,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,transient expression vector pFF19,,RP,24586999,PubMed,10.1371/journal.pone.0089738,PLoS One. 2014 Feb 24;9(2):e89738,mark.gijzen@agr.gc.ca,"Transient expression ofAvr1c or Avr1a triggers cell death on Rps1c plants, but Avr1c does not trigger cell death on Rps1a plants.",R Na 2014,2014,2 genes,Na-2014-Genome re-sequencing and functional an,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6576,PHI:5106,UniProt,A4LAA7,GenBank,ABO48503,,,P6497,Avr1c,,,,,,,67593,Phytophthora sojae,,P7076,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,transient expression vector pFF19,,RP,24586999,PubMed,10.1371/journal.pone.0089738,PLoS One. 2014 Feb 24;9(2):e89738,mark.gijzen@agr.gc.ca,"Transient expression ofAvr1c or Avr1a triggers cell death on Rps1c plants, but Avr1c does not trigger cell death on Rps1a plants.",R Na 2014,2014,2 genes,Na-2014-Genome re-sequencing and functional an,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6577,PHI:5107,UniProt,A4L9T6,GenBank,ABO47652,,,P6497,Avr1a,,,,,,,67593,Phytophthora sojae,,P7076,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Harosoy,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,transient expression vector pFF19,,RP,24586999,PubMed,10.1371/journal.pone.0089738,PLoS One. 2014 Feb 24;9(2):e89738,mark.gijzen@agr.gc.ca,"Transient expression ofAvr1c or Avr1a triggers cell death on Rps1c plants, but Avr1c does not trigger cell death on Rps1a plants.",R Na 2014,2014,2 genes,Na-2014-Genome re-sequencing and functional an,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6578,PHI:5108,UniProt,A0A0C9CDU9,GenBank,CET34985,,,Ke469,wbaV,,,,,,,28901,Salmonella enterica,550537,subsp. enterica serovar Enteritidis strain P125109,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; cecum,OAg biosynthesis,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26346801,PubMed,10.1186/s13099-015-0070-4,Gut Pathog. 2015 Sep 3;7:24,msbiotek@yahoo.com,The deltawbaV mutant also showed increased adhesion and invasion as compared to the other two O-Ag negative mutants deltatyv and deltaprt. In vivo experiments also confirmed the increased virulent phenotype of deltawbaV mutant as compared to deltaprt mutant.,S Jaiswal 2015,2015,2 genes,Jaiswal-2015-The O-antigen negative wbaV mutan,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6579,PHI:5109,UniProt,B5QZL1,GenBank,CAR33649,,,P125109,prt,,,,,,,28901,Salmonella enterica,550537,subsp. enterica serovar Enteritidis strain P125109,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; cecum,OAg biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26346801,PubMed,10.1186/s13099-015-0070-4,Gut Pathog. 2015 Sep 3;7:24,msbiotek@yahoo.com,The deltawbaV mutant also showed increased adhesion and invasion as compared to the other two O-Ag negative mutants deltatyv and deltaprt. In vivo experiments also confirmed the increased virulent phenotype of deltawbaV mutant as compared to deltaprt mutant.,S Jaiswal 2015,2015,2 genes,Jaiswal-2015-The O-antigen negative wbaV mutan,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6580,PHI:5110,UniProt,E8XL13,GenBank,ADX18667,,,ST4/74,SipB,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,pathogenicity island 1 effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26341924,PubMed,10.1007/s00284-015-0903-x,Curr Microbiol. 2015 Dec;71(6):687-92,cjzhang@sina.com,"The results showed that the SipB does not affect the growth ofSalmonella,but the adherence, invasion, and virulence of the mutant were significantly decreased compared with wild-type S.Typhimurium (SL1344).",S Chen 2015,2015,1 gene,Chen-2015-Deletion of Invasion Protein B in Sa,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6581,PHI:5111,UniProt,N4VSY8,GenBank,ENH87037,,,MAFF 240422,FAM1,,,,CoHex1; CoWsc,UniProt: N4UJP9; UniProt: N4VZG1,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,peroxisomal biogenesis gene,,,,loss of pathogenicity,,yes,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26374121,PubMed,10.1128/mBio.01305-15,MBio. 2015 Sep 15;6(5). pii: e01305-15,"Kubo, y_kubo@kpu.ac.jp","The fam1 disrupted mutants were unable to grow on medium containing oleic acids as the sole carbon source and were nonpathogenic, being defective in both appressorium melanization and host penetration.",Y Kubo 2015,2015,1 gene,Kubo-2015-Colletotrichum orbiculare FAM1 Encod,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6582,PHI:5112,UniProt,C0LF23,GenBank,ACN59479,,,P6497,Avr3c,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,stem,RXLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,19440541,PubMed,10.1371/journal.pone.0005556,PLoS One. 2009;4(5):e5556,mark.gijzen@agr.gc.ca,Gain of virulence was acquired through mutation and subsequent sequence exchanges between the two copies of Avr3c.,S Dong 2009,2009,1 gene,Dong-2009-The Phytophthora sojae avirulence lo,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6583,PHI:5113,UniProt,D0NVB5,GenBank,EEY66592,,,T30-4,AVR1,,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,RXLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,plasmids for transient expression assays were transformed into Agrobacterium tumefaciens strain AGL1 by electroporation,,RP,26336092,PubMed,10.1104/pp.15.01169,Plant Physiol. 2015 Sep 2. pii: pp.01169.2015,Francine.Govers@wur.nl,"P. infestans manipulates an plant exocyst subunit Sec5 and thereby potentially disturbs vesicle trafficking, a cellular process that is important for basal defence. This is a novel strategy that oomycete pathogens exploit to modulate host defence.",Y Du 2015,2015,1 gene,Du-2015-Phytophthora infestans RXLR effector A,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6584,PHI:5114,UniProt,Q8XYN5,GenBank,CAD15425,,,GMI1000,RSc1723,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6585,PHI:5115,UniProt,Q8XVD4,GenBank,CAD16604,,,GMI1000,RSc2897,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6586,PHI:5116,UniProt,Q8XT98,GenBank,CAD17367,,,GMI1000,RSp0216,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6587,PHI:5117,UniProt,Q8XT97,GenBank,CAD17369,,,GMI1000,RSp0218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6588,PHI:5118,UniProt,Q8XRI0,GenBank,CAD18005,,,GMI1000,RSp0854,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6589,PHI:5119,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6590,PHI:5120,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6591,PHI:5121,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6592,PHI:5122,UniProt,Q8XXL2,GenBank,CAD15808,,,GMI1000,RSc2101,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6593,PHI:5123,UniProt,Q8XQK6,GenBank,CAD18369,,,GMI1000,RSp1218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6594,PHI:5124,UniProt,Q8XQK7,GenBank,CAD18366,,,GMI1000,RSp1215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6595,PHI:5125,UniProt,Q8XQA2,GenBank,CAD18535,,,GMI1000,RSp1384,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6596,PHI:5126,UniProt,Q8XQ26,GenBank,CAD18611,,,GMI1000,RSp1460,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6597,PHI:5127,UniProt,Q8XSA6,GenBank,CAD17723,,,GMI1000,RSp0572,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6598,PHI:5128,UniProt,Q8XR46,GenBank,CAD18173,,,GMI1000,RSp1022,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6599,PHI:5129,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6600,PHI:5130,UniProt,Q8XT13,GenBank,CAD17455,,,GMI1000,RSp0304,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6601,PHI:5131,UniProt,Q8XU25,GenBank,CAD16866,,,GMI1000,RSc3369,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6602,PHI:5132,UniProt,Q8XTS6,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6603,PHI:5133,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6604,PHI:5134,UniProt,Q8XYF7,GenBank,CAD15503,,,GMI1000,RSc1801,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6605,PHI:5135,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6606,PHI:5136,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6607,PHI:5137,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6608,PHI:5138,UniProt,Q8XQT8,GenBank,CAD18281,,,GMI1000,RSp1130,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6609,PHI:5139,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6610,PHI:5140,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,RSc0868,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6611,PHI:5141,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6612,PHI:5142,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6613,PHI:5143,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6614,PHI:5144,UniProt,Q8XVQ5,GenBank,CAD16482,,,GMI1000,RSc2775,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6615,PHI:5145,UniProt,Q9RBS0,GenBank,CAB58262,,,GMI1000,RSp0877,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6616,PHI:5146,,no data found,,,,,,BA02498,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6617,PHI:5147,,no data found,,,,,,BA07003,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6618,PHI:5148,,no data found,,,,,,PT00619,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6619,PHI:5149,,no data found,,,,,,PT01265,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6620,PHI:5150,,no data found,,,,,,PT03045,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6621,PHI:5151,,no data found,,,,,,PT03558,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6622,PHI:5152,,no data found,,,,,,PT04098,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6623,PHI:5153,,no data found,,,,,,PT04281,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6624,PHI:5154,,no data found,,,,,,PT04284,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6625,PHI:5155,,no data found,,,,,,PT07000,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6626,PHI:5156,,no data found,,,,,,PT07001,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6627,PHI:5157,,no data found,,,,,,RSc2131,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6628,PHI:5158,UniProt,Q8XUL4,GenBank,CAD16962,,,GMI1000,RSc3174,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6629,PHI:5159,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,RSp0213,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6630,PHI:5160,UniProt,C0SPN9,GenBank,BAH47286,,,GMI1000,RSc2139,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6631,PHI:5161,,no data found,,,,,,PT01391,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6632,PHI:5162,UniProt,Q8Y2L4,GenBank,CAD13849,,,GMI1000,RSc0321,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6633,PHI:5163,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6634,PHI:5164,UniProt,Q8Y0Z8,GenBank,CAD14597,,,GMI1000,RSc0895,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6635,PHI:5165,UniProt,Q8XWW1,GenBank,CAD16066,,,GMI1000,RSc2359,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6636,PHI:5166,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6637,PHI:5167,,no data found,,,,,,PT04502,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6638,PHI:5168,,no data found,,,,,,PT04434,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6639,PHI:5169,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6640,PHI:5170,,no data found,,,,,,PT04834,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6641,PHI:5171,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6642,PHI:5172,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6643,PHI:5173,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6644,PHI:5174,UniProt,Q8XXI2,GenBank,CAD15839,,,GMI1000,RSc2132,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6645,PHI:5175,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6646,PHI:5176,,no data found,,,,,,BA00250,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6647,PHI:5177,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6648,PHI:5178,UniProt,Q8XUH6,GenBank,CAD17000,,,GMI1000,RSc3212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6649,PHI:5179,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6650,PHI:5180,,no data found,,,,,,PT03560,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6651,PHI:5181,UniProt,Q8XQL0,GenBank,CAD18363,,,GMI1000,RSp1212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6652,PHI:5182,,no data found,,,,,,PT01326,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Dingras Multiple Purple,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6653,PHI:5114,UniProt,Q8XYN5,GenBank,CAD15425,,,GMI1000,RSc1723,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6654,PHI:5115,UniProt,Q8XVD4,GenBank,CAD16604,,,GMI1000,RSc2897,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6655,PHI:5116,UniProt,Q8XT98,GenBank,CAD17367,,,GMI1000,RSp0216,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6656,PHI:5117,UniProt,Q8XT97,GenBank,CAD17369,,,GMI1000,RSp0218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6657,PHI:5118,UniProt,Q8XRI0,GenBank,CAD18005,,,GMI1000,RSp0854,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6658,PHI:5119,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6659,PHI:5120,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6660,PHI:5121,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6661,PHI:5122,UniProt,Q8XXL2,GenBank,CAD15808,,,GMI1000,RSc2101,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6662,PHI:5123,UniProt,Q8XQK6,GenBank,CAD18369,,,GMI1000,RSp1218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6663,PHI:5124,UniProt,Q8XQK7,GenBank,CAD18366,,,GMI1000,RSp1215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6664,PHI:5125,UniProt,Q8XQA2,GenBank,CAD18535,,,GMI1000,RSp1384,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6665,PHI:5126,UniProt,Q8XQ26,GenBank,CAD18611,,,GMI1000,RSp1460,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6666,PHI:5127,UniProt,Q8XSA6,GenBank,CAD17723,,,GMI1000,RSp0572,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6667,PHI:5128,UniProt,Q8XR46,GenBank,CAD18173,,,GMI1000,RSp1022,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6668,PHI:5129,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6669,PHI:5130,UniProt,Q8XT13,GenBank,CAD17455,,,GMI1000,RSp0304,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6670,PHI:5131,UniProt,Q8XU25,GenBank,CAD16866,,,GMI1000,RSc3369,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6671,PHI:5132,UniProt,Q8XTS6,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6672,PHI:5133,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6673,PHI:5134,UniProt,Q8XYF7,GenBank,CAD15503,,,GMI1000,RSc1801,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6674,PHI:5135,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6675,PHI:5136,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6676,PHI:5137,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6677,PHI:5138,UniProt,Q8XQT8,GenBank,CAD18281,,,GMI1000,RSp1130,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6678,PHI:5139,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6679,PHI:5140,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,RSc0868,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6680,PHI:5141,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6681,PHI:5142,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6682,PHI:5143,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6683,PHI:5144,UniProt,Q8XVQ5,GenBank,CAD16482,,,GMI1000,RSc2775,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6684,PHI:5145,UniProt,Q9RBS0,GenBank,CAB58262,,,GMI1000,RSp0877,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6685,PHI:5146,,no data found,,,,,,BA02498,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6686,PHI:5147,,no data found,,,,,,BA07003,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6687,PHI:5148,,no data found,,,,,,PT00619,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6688,PHI:5149,,no data found,,,,,,PT01265,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6689,PHI:5150,,no data found,,,,,,PT03045,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6690,PHI:5151,,no data found,,,,,,PT03558,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6691,PHI:5152,,no data found,,,,,,PT04098,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6692,PHI:5153,,no data found,,,,,,PT04281,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6693,PHI:5154,,no data found,,,,,,PT04284,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6694,PHI:5155,,no data found,,,,,,PT07000,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6695,PHI:5156,,no data found,,,,,,PT07001,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6696,PHI:5157,,no data found,,,,,,RSc2131,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6697,PHI:5158,UniProt,Q8XUL4,GenBank,CAD16962,,,GMI1000,RSc3174,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6698,PHI:5159,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,RSp0213,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6699,PHI:5160,UniProt,C0SPN9,GenBank,BAH47286,,,GMI1000,RSc2139,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.75. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6700,PHI:5161,,no data found,,,,,,PT01391,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6701,PHI:5162,UniProt,Q8Y2L4,GenBank,CAD13849,,,GMI1000,RSc0321,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6702,PHI:5163,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6703,PHI:5164,UniProt,Q8Y0Z8,GenBank,CAD14597,,,GMI1000,RSc0895,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6704,PHI:5165,UniProt,Q8XWW1,GenBank,CAD16066,,,GMI1000,RSc2359,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6705,PHI:5166,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6706,PHI:5167,,no data found,,,,,,PT04502,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6707,PHI:5168,,no data found,,,,,,PT04434,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6708,PHI:5169,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6709,PHI:5170,,no data found,,,,,,PT04834,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6710,PHI:5171,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6711,PHI:5172,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6712,PHI:5173,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6713,PHI:5174,UniProt,Q8XXI2,GenBank,CAD15839,,,GMI1000,RSc2132,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6714,PHI:5175,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6715,PHI:5176,,no data found,,,,,,BA00250,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6716,PHI:5177,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6717,PHI:5178,UniProt,Q8XUH6,GenBank,CAD17000,,,GMI1000,RSc3212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6718,PHI:5179,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.6. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6719,PHI:5180,,no data found,,,,,,PT03560,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6720,PHI:5181,UniProt,Q8XQL0,GenBank,CAD18363,,,GMI1000,RSp1212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6721,PHI:5182,,no data found,,,,,,PT01326,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. SM6,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6722,PHI:5114,UniProt,Q8XYN5,GenBank,CAD15425,,,GMI1000,RSc1723,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6723,PHI:5115,UniProt,Q8XVD4,GenBank,CAD16604,,,GMI1000,RSc2897,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6724,PHI:5116,UniProt,Q8XT98,GenBank,CAD17367,,,GMI1000,RSp0216,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6725,PHI:5117,UniProt,Q8XT97,GenBank,CAD17369,,,GMI1000,RSp0218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6726,PHI:5118,UniProt,Q8XRI0,GenBank,CAD18005,,,GMI1000,RSp0854,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6727,PHI:5119,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6728,PHI:5120,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6729,PHI:5121,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6730,PHI:5122,UniProt,Q8XXL2,GenBank,CAD15808,,,GMI1000,RSc2101,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6731,PHI:5123,UniProt,Q8XQK6,GenBank,CAD18369,,,GMI1000,RSp1218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6732,PHI:5124,UniProt,Q8XQK7,GenBank,CAD18366,,,GMI1000,RSp1215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6733,PHI:5125,UniProt,Q8XQA2,GenBank,CAD18535,,,GMI1000,RSp1384,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6734,PHI:5126,UniProt,Q8XQ26,GenBank,CAD18611,,,GMI1000,RSp1460,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6735,PHI:5127,UniProt,Q8XSA6,GenBank,CAD17723,,,GMI1000,RSp0572,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6736,PHI:5128,UniProt,Q8XR46,GenBank,CAD18173,,,GMI1000,RSp1022,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6737,PHI:5129,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6738,PHI:5130,UniProt,Q8XT13,GenBank,CAD17455,,,GMI1000,RSp0304,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6739,PHI:5131,UniProt,Q8XU25,GenBank,CAD16866,,,GMI1000,RSc3369,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6740,PHI:5132,UniProt,Q8XTS6,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6741,PHI:5133,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6742,PHI:5134,UniProt,Q8XYF7,GenBank,CAD15503,,,GMI1000,RSc1801,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6743,PHI:5135,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6744,PHI:5136,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6745,PHI:5137,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6746,PHI:5138,UniProt,Q8XQT8,GenBank,CAD18281,,,GMI1000,RSp1130,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6747,PHI:5139,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6748,PHI:5140,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,RSc0868,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6749,PHI:5141,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6750,PHI:5142,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6751,PHI:5143,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6752,PHI:5144,UniProt,Q8XVQ5,GenBank,CAD16482,,,GMI1000,RSc2775,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6753,PHI:5145,UniProt,Q9RBS0,GenBank,CAB58262,,,GMI1000,RSp0877,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6754,PHI:5146,,no data found,,,,,,BA02498,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6755,PHI:5147,,no data found,,,,,,BA07003,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6756,PHI:5148,,no data found,,,,,,PT00619,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6757,PHI:5149,,no data found,,,,,,PT01265,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6758,PHI:5150,,no data found,,,,,,PT03045,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6759,PHI:5151,,no data found,,,,,,PT03558,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6760,PHI:5152,,no data found,,,,,,PT04098,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6761,PHI:5153,,no data found,,,,,,PT04281,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6762,PHI:5154,,no data found,,,,,,PT04284,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6763,PHI:5155,,no data found,,,,,,PT07000,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6764,PHI:5156,,no data found,,,,,,PT07001,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6765,PHI:5157,,no data found,,,,,,RSc2131,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6766,PHI:5158,UniProt,Q8XUL4,GenBank,CAD16962,,,GMI1000,RSc3174,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6767,PHI:5159,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,RSp0213,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6768,PHI:5160,UniProt,C0SPN9,GenBank,BAH47286,,,GMI1000,RSc2139,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6769,PHI:5161,,no data found,,,,,,PT01391,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6770,PHI:5162,UniProt,Q8Y2L4,GenBank,CAD13849,,,GMI1000,RSc0321,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6771,PHI:5163,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6772,PHI:5164,UniProt,Q8Y0Z8,GenBank,CAD14597,,,GMI1000,RSc0895,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6773,PHI:5165,UniProt,Q8XWW1,GenBank,CAD16066,,,GMI1000,RSc2359,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6774,PHI:5166,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6775,PHI:5167,,no data found,,,,,,PT04502,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6776,PHI:5168,,no data found,,,,,,PT04434,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6777,PHI:5169,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6778,PHI:5170,,no data found,,,,,,PT04834,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6779,PHI:5171,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6780,PHI:5172,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6781,PHI:5173,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6782,PHI:5174,UniProt,Q8XXI2,GenBank,CAD15839,,,GMI1000,RSc2132,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6783,PHI:5175,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6784,PHI:5176,,no data found,,,,,,BA00250,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6785,PHI:5177,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6786,PHI:5178,UniProt,Q8XUH6,GenBank,CAD17000,,,GMI1000,RSc3212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6787,PHI:5179,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6788,PHI:5180,,no data found,,,,,,PT03560,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6789,PHI:5181,UniProt,Q8XQL0,GenBank,CAD18363,,,GMI1000,RSp1212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6790,PHI:5182,,no data found,,,,,,PT01326,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Ceylan,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6791,PHI:5114,UniProt,Q8XYN5,GenBank,CAD15425,,,GMI1000,RSc1723,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6792,PHI:5115,UniProt,Q8XVD4,GenBank,CAD16604,,,GMI1000,RSc2897,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6793,PHI:5116,UniProt,Q8XT98,GenBank,CAD17367,,,GMI1000,RSp0216,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6794,PHI:5117,UniProt,Q8XT97,GenBank,CAD17369,,,GMI1000,RSp0218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6795,PHI:5118,UniProt,Q8XRI0,GenBank,CAD18005,,,GMI1000,RSp0854,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6796,PHI:5119,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6797,PHI:5120,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6798,PHI:5121,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6799,PHI:5122,UniProt,Q8XXL2,GenBank,CAD15808,,,GMI1000,RSc2101,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6800,PHI:5123,UniProt,Q8XQK6,GenBank,CAD18369,,,GMI1000,RSp1218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6801,PHI:5124,UniProt,Q8XQK7,GenBank,CAD18366,,,GMI1000,RSp1215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6802,PHI:5125,UniProt,Q8XQA2,GenBank,CAD18535,,,GMI1000,RSp1384,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6803,PHI:5126,UniProt,Q8XQ26,GenBank,CAD18611,,,GMI1000,RSp1460,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6804,PHI:5127,UniProt,Q8XSA6,GenBank,CAD17723,,,GMI1000,RSp0572,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6805,PHI:5128,UniProt,Q8XR46,GenBank,CAD18173,,,GMI1000,RSp1022,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6806,PHI:5129,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6807,PHI:5130,UniProt,Q8XT13,GenBank,CAD17455,,,GMI1000,RSp0304,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6808,PHI:5131,UniProt,Q8XU25,GenBank,CAD16866,,,GMI1000,RSc3369,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6809,PHI:5132,UniProt,Q8XTS6,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6810,PHI:5133,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6811,PHI:5134,UniProt,Q8XYF7,GenBank,CAD15503,,,GMI1000,RSc1801,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6812,PHI:5135,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6813,PHI:5136,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6814,PHI:5137,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6815,PHI:5138,UniProt,Q8XQT8,GenBank,CAD18281,,,GMI1000,RSp1130,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6816,PHI:5139,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6817,PHI:5140,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,RSc0868,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6818,PHI:5141,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6819,PHI:5142,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6820,PHI:5143,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6821,PHI:5144,UniProt,Q8XVQ5,GenBank,CAD16482,,,GMI1000,RSc2775,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6822,PHI:5145,UniProt,Q9RBS0,GenBank,CAB58262,,,GMI1000,RSp0877,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6823,PHI:5146,,no data found,,,,,,BA02498,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6824,PHI:5147,,no data found,,,,,,BA07003,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6825,PHI:5148,,no data found,,,,,,PT00619,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6826,PHI:5149,,no data found,,,,,,PT01265,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6827,PHI:5150,,no data found,,,,,,PT03045,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6828,PHI:5151,,no data found,,,,,,PT03558,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6829,PHI:5152,,no data found,,,,,,PT04098,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6830,PHI:5153,,no data found,,,,,,PT04281,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6831,PHI:5154,,no data found,,,,,,PT04284,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6832,PHI:5155,,no data found,,,,,,PT07000,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6833,PHI:5156,,no data found,,,,,,PT07001,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6834,PHI:5157,,no data found,,,,,,RSc2131,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6835,PHI:5158,UniProt,Q8XUL4,GenBank,CAD16962,,,GMI1000,RSc3174,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6836,PHI:5159,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,RSp0213,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6837,PHI:5160,UniProt,C0SPN9,GenBank,BAH47286,,,GMI1000,RSc2139,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6838,PHI:5161,,no data found,,,,,,PT01391,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6839,PHI:5162,UniProt,Q8Y2L4,GenBank,CAD13849,,,GMI1000,RSc0321,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6840,PHI:5163,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6841,PHI:5164,UniProt,Q8Y0Z8,GenBank,CAD14597,,,GMI1000,RSc0895,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6842,PHI:5165,UniProt,Q8XWW1,GenBank,CAD16066,,,GMI1000,RSc2359,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6843,PHI:5166,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6844,PHI:5167,,no data found,,,,,,PT04502,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6845,PHI:5168,,no data found,,,,,,PT04434,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6846,PHI:5169,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6847,PHI:5170,,no data found,,,,,,PT04834,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6848,PHI:5171,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6849,PHI:5172,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6850,PHI:5173,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6851,PHI:5174,UniProt,Q8XXI2,GenBank,CAD15839,,,GMI1000,RSc2132,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6852,PHI:5175,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6853,PHI:5176,,no data found,,,,,,BA00250,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6854,PHI:5177,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6855,PHI:5178,UniProt,Q8XUH6,GenBank,CAD17000,,,GMI1000,RSc3212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6856,PHI:5179,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6857,PHI:5180,,no data found,,,,,,PT03560,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6858,PHI:5181,UniProt,Q8XQL0,GenBank,CAD18363,,,GMI1000,RSp1212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6859,PHI:5182,,no data found,,,,,,PT01326,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Surya,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6860,PHI:5114,UniProt,Q8XYN5,GenBank,CAD15425,,,GMI1000,RSc1723,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6861,PHI:5115,UniProt,Q8XVD4,GenBank,CAD16604,,,GMI1000,RSc2897,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6862,PHI:5116,UniProt,Q8XT98,GenBank,CAD17367,,,GMI1000,RSp0216,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6863,PHI:5117,UniProt,Q8XT97,GenBank,CAD17369,,,GMI1000,RSp0218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6864,PHI:5118,UniProt,Q8XRI0,GenBank,CAD18005,,,GMI1000,RSp0854,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6865,PHI:5119,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6866,PHI:5120,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6867,PHI:5121,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6868,PHI:5122,UniProt,Q8XXL2,GenBank,CAD15808,,,GMI1000,RSc2101,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6869,PHI:5123,UniProt,Q8XQK6,GenBank,CAD18369,,,GMI1000,RSp1218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6870,PHI:5124,UniProt,Q8XQK7,GenBank,CAD18366,,,GMI1000,RSp1215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6871,PHI:5125,UniProt,Q8XQA2,GenBank,CAD18535,,,GMI1000,RSp1384,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6872,PHI:5126,UniProt,Q8XQ26,GenBank,CAD18611,,,GMI1000,RSp1460,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6873,PHI:5127,UniProt,Q8XSA6,GenBank,CAD17723,,,GMI1000,RSp0572,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6874,PHI:5128,UniProt,Q8XR46,GenBank,CAD18173,,,GMI1000,RSp1022,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6875,PHI:5129,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6876,PHI:5130,UniProt,Q8XT13,GenBank,CAD17455,,,GMI1000,RSp0304,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6877,PHI:5131,UniProt,Q8XU25,GenBank,CAD16866,,,GMI1000,RSc3369,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6878,PHI:5132,UniProt,Q8XTS6,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6879,PHI:5133,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6880,PHI:5134,UniProt,Q8XYF7,GenBank,CAD15503,,,GMI1000,RSc1801,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6881,PHI:5135,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6882,PHI:5136,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6883,PHI:5137,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6884,PHI:5138,UniProt,Q8XQT8,GenBank,CAD18281,,,GMI1000,RSp1130,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6885,PHI:5139,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6886,PHI:5140,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,RSc0868,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.75. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6887,PHI:5141,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.2. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6888,PHI:5142,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6889,PHI:5143,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6890,PHI:5144,UniProt,Q8XVQ5,GenBank,CAD16482,,,GMI1000,RSc2775,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6891,PHI:5145,UniProt,Q9RBS0,GenBank,CAB58262,,,GMI1000,RSp0877,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6892,PHI:5146,,no data found,,,,,,BA02498,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6893,PHI:5147,,no data found,,,,,,BA07003,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6894,PHI:5148,,no data found,,,,,,PT00619,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6895,PHI:5149,,no data found,,,,,,PT01265,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6896,PHI:5150,,no data found,,,,,,PT03045,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6897,PHI:5151,,no data found,,,,,,PT03558,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6898,PHI:5152,,no data found,,,,,,PT04098,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6899,PHI:5153,,no data found,,,,,,PT04281,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6900,PHI:5154,,no data found,,,,,,PT04284,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6901,PHI:5155,,no data found,,,,,,PT07000,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6902,PHI:5156,,no data found,,,,,,PT07001,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6903,PHI:5157,,no data found,,,,,,RSc2131,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6904,PHI:5158,UniProt,Q8XUL4,GenBank,CAD16962,,,GMI1000,RSc3174,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6905,PHI:5159,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,RSp0213,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6906,PHI:5160,UniProt,C0SPN9,GenBank,BAH47286,,,GMI1000,RSc2139,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6907,PHI:5161,,no data found,,,,,,PT01391,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6908,PHI:5162,UniProt,Q8Y2L4,GenBank,CAD13849,,,GMI1000,RSc0321,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6909,PHI:5163,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6910,PHI:5164,UniProt,Q8Y0Z8,GenBank,CAD14597,,,GMI1000,RSc0895,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6911,PHI:5165,UniProt,Q8XWW1,GenBank,CAD16066,,,GMI1000,RSc2359,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6912,PHI:5166,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6913,PHI:5167,,no data found,,,,,,PT04502,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6914,PHI:5168,,no data found,,,,,,PT04434,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6915,PHI:5169,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6916,PHI:5170,,no data found,,,,,,PT04834,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6917,PHI:5171,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6918,PHI:5172,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6919,PHI:5173,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6920,PHI:5174,UniProt,Q8XXI2,GenBank,CAD15839,,,GMI1000,RSc2132,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6921,PHI:5175,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6922,PHI:5176,,no data found,,,,,,BA00250,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6923,PHI:5177,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6924,PHI:5178,UniProt,Q8XUH6,GenBank,CAD17000,,,GMI1000,RSc3212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6925,PHI:5179,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6926,PHI:5180,,no data found,,,,,,PT03560,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6927,PHI:5181,UniProt,Q8XQL0,GenBank,CAD18363,,,GMI1000,RSp1212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6928,PHI:5182,,no data found,,,,,,PT01326,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. AG91-25,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6929,PHI:5146,,no data found,,,,,,BA02498,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6930,PHI:5147,,no data found,,,,,,BA07003,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6931,PHI:5148,,no data found,,,,,,PT00619,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6932,PHI:5149,,no data found,,,,,,PT01265,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6933,PHI:5150,,no data found,,,,,,PT03045,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6934,PHI:5151,,no data found,,,,,,PT03558,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6935,PHI:5152,,no data found,,,,,,PT04098,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6936,PHI:5153,,no data found,,,,,,PT04281,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6937,PHI:5154,,no data found,,,,,,PT04284,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6938,PHI:5155,,no data found,,,,,,PT07000,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6939,PHI:5156,,no data found,,,,,,PT07001,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6940,PHI:5157,,no data found,,,,,,RSc2131,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6941,PHI:5158,UniProt,Q8XUL4,GenBank,CAD16962,,,GMI1000,RSc3174,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6942,PHI:5159,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,RSp0213,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6943,PHI:5160,UniProt,C0SPN9,GenBank,BAH47286,,,GMI1000,RSc2139,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6944,PHI:5161,,no data found,,,,,,PT01391,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6945,PHI:5162,UniProt,Q8Y2L4,GenBank,CAD13849,,,GMI1000,RSc0321,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6946,PHI:5163,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6947,PHI:5164,UniProt,Q8Y0Z8,GenBank,CAD14597,,,GMI1000,RSc0895,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6948,PHI:5165,UniProt,Q8XWW1,GenBank,CAD16066,,,GMI1000,RSc2359,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6949,PHI:5166,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6950,PHI:5167,,no data found,,,,,,PT04502,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6951,PHI:5168,,no data found,,,,,,PT04434,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6952,PHI:5169,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6953,PHI:5170,,no data found,,,,,,PT04834,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.75. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6954,PHI:5171,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6955,PHI:5172,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6956,PHI:5173,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6957,PHI:5174,UniProt,Q8XXI2,GenBank,CAD15839,,,GMI1000,RSc2132,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6958,PHI:5175,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6959,PHI:5176,,no data found,,,,,,BA00250,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6960,PHI:5177,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6961,PHI:5178,UniProt,Q8XUH6,GenBank,CAD17000,,,GMI1000,RSc3212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6962,PHI:5179,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6963,PHI:5180,,no data found,,,,,,PT03560,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6964,PHI:5181,UniProt,Q8XQL0,GenBank,CAD18363,,,GMI1000,RSp1212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.8. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6965,PHI:5182,,no data found,,,,,,PT01326,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM687,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6966,PHI:5146,,no data found,,,,,,BA02498,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6967,PHI:5147,,no data found,,,,,,BA07003,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6968,PHI:5148,,no data found,,,,,,PT00619,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6969,PHI:5149,,no data found,,,,,,PT01265,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6970,PHI:5150,,no data found,,,,,,PT03045,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6971,PHI:5151,,no data found,,,,,,PT03558,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6972,PHI:5152,,no data found,,,,,,PT04098,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6973,PHI:5153,,no data found,,,,,,PT04281,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6974,PHI:5154,,no data found,,,,,,PT04284,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6975,PHI:5155,,no data found,,,,,,PT07000,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6976,PHI:5156,,no data found,,,,,,PT07001,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6977,PHI:5157,,no data found,,,,,,RSc2131,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6978,PHI:5158,UniProt,Q8XUL4,GenBank,CAD16962,,,GMI1000,RSc3174,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6979,PHI:5159,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,RSp0213,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6980,PHI:5160,UniProt,C0SPN9,GenBank,BAH47286,,,GMI1000,RSc2139,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6981,PHI:5161,,no data found,,,,,,PT01391,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6982,PHI:5162,UniProt,Q8Y2L4,GenBank,CAD13849,,,GMI1000,RSc0321,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6983,PHI:5163,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6984,PHI:5164,UniProt,Q8Y0Z8,GenBank,CAD14597,,,GMI1000,RSc0895,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6985,PHI:5165,UniProt,Q8XWW1,GenBank,CAD16066,,,GMI1000,RSc2359,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6986,PHI:5166,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6987,PHI:5167,,no data found,,,,,,PT04502,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6988,PHI:5168,,no data found,,,,,,PT04434,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6989,PHI:5169,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6990,PHI:5170,,no data found,,,,,,PT04834,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6991,PHI:5171,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6992,PHI:5172,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6993,PHI:5173,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6994,PHI:5174,UniProt,Q8XXI2,GenBank,CAD15839,,,GMI1000,RSc2132,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6995,PHI:5175,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6996,PHI:5176,,no data found,,,,,,BA00250,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6997,PHI:5177,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6998,PHI:5178,UniProt,Q8XUH6,GenBank,CAD17000,,,GMI1000,RSc3212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 6999,PHI:5179,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7000,PHI:5180,,no data found,,,,,,PT03560,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7001,PHI:5181,UniProt,Q8XQL0,GenBank,CAD18363,,,GMI1000,RSp1212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7002,PHI:5182,,no data found,,,,,,PT01326,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. CA8,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7003,PHI:5114,UniProt,Q8XYN5,GenBank,CAD15425,,,GMI1000,RSc1723,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7004,PHI:5115,UniProt,Q8XVD4,GenBank,CAD16604,,,GMI1000,RSc2897,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7005,PHI:5116,UniProt,Q8XT98,GenBank,CAD17367,,,GMI1000,RSp0216,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7006,PHI:5117,UniProt,Q8XT97,GenBank,CAD17369,,,GMI1000,RSp0218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.75. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7007,PHI:5118,UniProt,Q8XRI0,GenBank,CAD18005,,,GMI1000,RSp0854,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7008,PHI:5119,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7009,PHI:5120,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7010,PHI:5121,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7011,PHI:5122,UniProt,Q8XXL2,GenBank,CAD15808,,,GMI1000,RSc2101,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7012,PHI:5123,UniProt,Q8XQK6,GenBank,CAD18369,,,GMI1000,RSp1218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7013,PHI:5124,UniProt,Q8XQK7,GenBank,CAD18366,,,GMI1000,RSp1215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7014,PHI:5125,UniProt,Q8XQA2,GenBank,CAD18535,,,GMI1000,RSp1384,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.75. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7015,PHI:5126,UniProt,Q8XQ26,GenBank,CAD18611,,,GMI1000,RSp1460,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7016,PHI:5127,UniProt,Q8XSA6,GenBank,CAD17723,,,GMI1000,RSp0572,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7017,PHI:5128,UniProt,Q8XR46,GenBank,CAD18173,,,GMI1000,RSp1022,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7018,PHI:5129,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7019,PHI:5130,UniProt,Q8XT13,GenBank,CAD17455,,,GMI1000,RSp0304,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7020,PHI:5131,UniProt,Q8XU25,GenBank,CAD16866,,,GMI1000,RSc3369,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7021,PHI:5132,UniProt,Q8XTS6,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.6. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7022,PHI:5133,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7023,PHI:5134,UniProt,Q8XYF7,GenBank,CAD15503,,,GMI1000,RSc1801,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7024,PHI:5135,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7025,PHI:5136,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7026,PHI:5137,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7027,PHI:5138,UniProt,Q8XQT8,GenBank,CAD18281,,,GMI1000,RSp1130,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7028,PHI:5139,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7029,PHI:5140,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,RSc0868,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7030,PHI:5141,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7031,PHI:5142,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7032,PHI:5143,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.2. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7033,PHI:5144,UniProt,Q8XVQ5,GenBank,CAD16482,,,GMI1000,RSc2775,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7034,PHI:5145,UniProt,Q9RBS0,GenBank,CAB58262,,,GMI1000,RSp0877,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7035,PHI:5146,,no data found,,,,,,BA02498,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7036,PHI:5147,,no data found,,,,,,BA07003,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7037,PHI:5148,,no data found,,,,,,PT00619,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7038,PHI:5149,,no data found,,,,,,PT01265,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7039,PHI:5150,,no data found,,,,,,PT03045,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7040,PHI:5151,,no data found,,,,,,PT03558,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7041,PHI:5152,,no data found,,,,,,PT04098,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7042,PHI:5153,,no data found,,,,,,PT04281,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7043,PHI:5154,,no data found,,,,,,PT04284,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7044,PHI:5155,,no data found,,,,,,PT07000,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7045,PHI:5156,,no data found,,,,,,PT07001,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7046,PHI:5157,,no data found,,,,,,RSc2131,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7047,PHI:5158,UniProt,Q8XUL4,GenBank,CAD16962,,,GMI1000,RSc3174,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7048,PHI:5159,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,RSp0213,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7049,PHI:5160,UniProt,C0SPN9,GenBank,BAH47286,,,GMI1000,RSc2139,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7050,PHI:5161,,no data found,,,,,,PT01391,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7051,PHI:5162,UniProt,Q8Y2L4,GenBank,CAD13849,,,GMI1000,RSc0321,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.75. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7052,PHI:5163,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7053,PHI:5164,UniProt,Q8Y0Z8,GenBank,CAD14597,,,GMI1000,RSc0895,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7054,PHI:5165,UniProt,Q8XWW1,GenBank,CAD16066,,,GMI1000,RSc2359,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7055,PHI:5166,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7056,PHI:5167,,no data found,,,,,,PT04502,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7057,PHI:5168,,no data found,,,,,,PT04434,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7058,PHI:5169,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.75. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7059,PHI:5170,,no data found,,,,,,PT04834,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7060,PHI:5171,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7061,PHI:5172,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7062,PHI:5173,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7063,PHI:5174,UniProt,Q8XXI2,GenBank,CAD15839,,,GMI1000,RSc2132,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7064,PHI:5175,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7065,PHI:5176,,no data found,,,,,,BA00250,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.67. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7066,PHI:5177,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.4. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7067,PHI:5178,UniProt,Q8XUH6,GenBank,CAD17000,,,GMI1000,RSc3212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7068,PHI:5179,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7069,PHI:5180,,no data found,,,,,,PT03560,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7070,PHI:5181,UniProt,Q8XQL0,GenBank,CAD18363,,,GMI1000,RSp1212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7071,PHI:5182,,no data found,,,,,,PT01326,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4072,Capsicum annuum (no common name found),cv. PM659,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7072,PHI:5114,UniProt,Q8XYN5,GenBank,CAD15425,,,GMI1000,RSc1723,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7073,PHI:5115,UniProt,Q8XVD4,GenBank,CAD16604,,,GMI1000,RSc2897,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7074,PHI:5116,UniProt,Q8XT98,GenBank,CAD17367,,,GMI1000,RSp0216,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7075,PHI:5117,UniProt,Q8XT97,GenBank,CAD17369,,,GMI1000,RSp0218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7076,PHI:5118,UniProt,Q8XRI0,GenBank,CAD18005,,,GMI1000,RSp0854,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7077,PHI:5119,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7078,PHI:5120,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7079,PHI:5121,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7080,PHI:5122,UniProt,Q8XXL2,GenBank,CAD15808,,,GMI1000,RSc2101,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7081,PHI:5123,UniProt,Q8XQK6,GenBank,CAD18369,,,GMI1000,RSp1218,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7082,PHI:5124,UniProt,Q8XQK7,GenBank,CAD18366,,,GMI1000,RSp1215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7083,PHI:5125,UniProt,Q8XQA2,GenBank,CAD18535,,,GMI1000,RSp1384,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7084,PHI:5126,UniProt,Q8XQ26,GenBank,CAD18611,,,GMI1000,RSp1460,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7085,PHI:5127,UniProt,Q8XSA6,GenBank,CAD17723,,,GMI1000,RSp0572,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.75. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7086,PHI:5128,UniProt,Q8XR46,GenBank,CAD18173,,,GMI1000,RSp1022,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7087,PHI:5129,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7088,PHI:5130,UniProt,Q8XT13,GenBank,CAD17455,,,GMI1000,RSp0304,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7089,PHI:5131,UniProt,Q8XU25,GenBank,CAD16866,,,GMI1000,RSc3369,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7090,PHI:5132,UniProt,Q8XTS6,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7091,PHI:5133,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7092,PHI:5134,UniProt,Q8XYF7,GenBank,CAD15503,,,GMI1000,RSc1801,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7093,PHI:5135,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7094,PHI:5136,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7095,PHI:5137,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7096,PHI:5138,UniProt,Q8XQT8,GenBank,CAD18281,,,GMI1000,RSp1130,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7097,PHI:5139,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7098,PHI:5140,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,RSc0868,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7099,PHI:5141,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7100,PHI:5142,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7101,PHI:5143,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7102,PHI:5144,UniProt,Q8XVQ5,GenBank,CAD16482,,,GMI1000,RSc2775,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7103,PHI:5145,UniProt,Q9RBS0,GenBank,CAB58262,,,GMI1000,RSp0877,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with avirulence as determined by ratio present probes/total probes per gene in 'avirulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of avirulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7104,PHI:5146,,no data found,,,,,,BA02498,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7105,PHI:5147,,no data found,,,,,,BA07003,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7106,PHI:5148,,no data found,,,,,,PT00619,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7107,PHI:5149,,no data found,,,,,,PT01265,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7108,PHI:5150,,no data found,,,,,,PT03045,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7109,PHI:5151,,no data found,,,,,,PT03558,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7110,PHI:5152,,no data found,,,,,,PT04098,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7111,PHI:5153,,no data found,,,,,,PT04281,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7112,PHI:5154,,no data found,,,,,,PT04284,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7113,PHI:5155,,no data found,,,,,,PT07000,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7114,PHI:5156,,no data found,,,,,,PT07001,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7115,PHI:5157,,no data found,,,,,,RSc2131,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7116,PHI:5158,UniProt,Q8XUL4,GenBank,CAD16962,,,GMI1000,RSc3174,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7117,PHI:5159,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,RSp0213,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7118,PHI:5160,UniProt,C0SPN9,GenBank,BAH47286,,,GMI1000,RSc2139,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7119,PHI:5161,,no data found,,,,,,PT01391,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 1. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7120,PHI:5162,UniProt,Q8Y2L4,GenBank,CAD13849,,,GMI1000,RSc0321,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7121,PHI:5163,UniProt,Q8XRK9,GenBank,CAD17973,,,GMI1000,RSp0822,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7122,PHI:5164,UniProt,Q8Y0Z8,GenBank,CAD14597,,,GMI1000,RSc0895,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7123,PHI:5165,UniProt,Q8XWW1,GenBank,CAD16066,,,GMI1000,RSc2359,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7124,PHI:5166,UniProt,Q8XPQ6,GenBank,CAD18733,,,GMI1000,RSp1582,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7125,PHI:5167,,no data found,,,,,,PT04502,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7126,PHI:5168,,no data found,,,,,,PT04434,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7127,PHI:5169,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7128,PHI:5170,,no data found,,,,,,PT04834,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7129,PHI:5171,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7130,PHI:5172,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7131,PHI:5173,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7132,PHI:5174,UniProt,Q8XXI2,GenBank,CAD15839,,,GMI1000,RSc2132,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7133,PHI:5175,UniProt,Q8Y164,GenBank,CAD14528,,,GMI1000,RSc0826,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7134,PHI:5176,,no data found,,,,,,BA00250,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7135,PHI:5177,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7136,PHI:5178,UniProt,Q8XUH6,GenBank,CAD17000,,,GMI1000,RSc3212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7137,PHI:5179,UniProt,Q8XYE3,GenBank,CAD15517,,,GMI1000,RSc1815,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7138,PHI:5180,,no data found,,,,,,PT03560,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.5. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7139,PHI:5181,UniProt,Q8XQL0,GenBank,CAD18363,,,GMI1000,RSp1212,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score <0.25. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7140,PHI:5182,,no data found,,,,,,PT01326,,,,,,,305,Ralstonia solanacearum,267608,,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,,type III effectors (T3E) and T3E-like genes,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: association genetics,,,RP,26368514,PubMed,10.1094/PHYTO-06-15-0140-R,Phytopathology. 2015 Sep 14,wicker@cirad.fr,Score 0.33. Type III effectors (T3E) and T3E-like genes associated with virulence as determined by ratio present probes/total probes per gene in 'virulent strain pool'. A score of at least 0.5 corresponding to 50% probes assumes association of virulence to at least one plant accession.,F Pensec 2015,2015,69 genes,Pensec-2015-Towards the identification of Type,BATCH_053,2015-10-01,MC,,,,,,,,,,,,,
,,Record 7141,PHI:5183,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,global regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26199376,PubMed,10.1093/molbev/msv160,Mol Biol Evol. 2015 Nov;32(11):2883-96,gjansen@zoologie.uni-kiel.de,,G Jansen 2015,2015,1 gene,Jansen-2015-Evolutionary Transition from Patho,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7142,PHI:5184,UniProt,C8TNS7,GenBank,BAI28410,,,11368,espZ,,,,,,,562,Escherichia coli,,ECB480,diarrhea,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,intestine,T3SS secreted effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25561713,PubMed,10.1128/IAI.02876-14,Infect Immun. 2015 Mar;83(3):1139-49,vkv@email.arizona.edu,,J S Wilbur 2015,2015,1 gene,Wilbur-2015-The secreted effector protein EspZ,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7143,PHI:5185,UniProt,G4NC17,GenBank,EHA49020,,,70-15,MoAPX1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,class I peroxidase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26134974,PubMed,10.1038/srep11831,Sci Rep. 2015 Jul 2;5:11831,yonglee@snu.ac.kr,"All seven mutants were sensitive to H2O2, suggesting that their ability to cope with oxidative stress was compromised to varying degrees.",A A Mir 2015,2015,7 genes,Mir-2015-Systematic characterization of the pe,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7144,PHI:5186,UniProt,G4MZ98,GenBank,EHA55371,,,70-15,MoAPX2,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,class I peroxidase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26134974,PubMed,10.1038/srep11831,Sci Rep. 2015 Jul 2;5:11831,yonglee@snu.ac.kr,"All seven mutants were sensitive to H2O2, suggesting that their ability to cope with oxidative stress was compromised to varying degrees.",A A Mir 2015,2015,7 genes,Mir-2015-Systematic characterization of the pe,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7145,PHI:5187,UniProt,A4QVH4,GenBank,EHA58330,,,70-15,MoCCP1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,class I peroxidase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26134974,PubMed,10.1038/srep11831,Sci Rep. 2015 Jul 2;5:11831,yonglee@snu.ac.kr,"All seven mutants were sensitive to H2O2, suggesting that their ability to cope with oxidative stress was compromised to varying degrees.",A A Mir 2015,2015,7 genes,Mir-2015-Systematic characterization of the pe,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7146,PHI:5188,UniProt,G4N3U4,GenBank,EHA52717,,,70-15,MoHPX1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,dye-type peroxidase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26134974,PubMed,10.1038/srep11831,Sci Rep. 2015 Jul 2;5:11831,yonglee@snu.ac.kr,"All seven mutants were sensitive to H2O2, suggesting that their ability to cope with oxidative stress was compromised to varying degrees.",A A Mir 2015,2015,7 genes,Mir-2015-Systematic characterization of the pe,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7147,PHI:5189,UniProt,G4N2X9,GenBank,EHA53428,,,70-15,MoLDS1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,animal peroxidase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26134974,PubMed,10.1038/srep11831,Sci Rep. 2015 Jul 2;5:11831,yonglee@snu.ac.kr,"All seven mutants were sensitive to H2O2, suggesting that their ability to cope with oxidative stress was compromised to varying degrees.",A A Mir 2015,2015,7 genes,Mir-2015-Systematic characterization of the pe,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7148,PHI:5190,UniProt,G4MXC5,GenBank,EHA56023,,,70-15,MoPRX1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,peroxiredoxin peroxidase,,,,reduced virulence,,no,no,yes,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26134974,PubMed,10.1038/srep11831,Sci Rep. 2015 Jul 2;5:11831,yonglee@snu.ac.kr,"All seven mutants were sensitive to H2O2, suggesting that their ability to cope with oxidative stress was compromised to varying degrees.",A A Mir 2015,2015,7 genes,Mir-2015-Systematic characterization of the pe,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7149,PHI:5191,UniProt,G4N1N6,GenBank,EHA51608,,,70-15,TPX1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,peroxiredoxin peroxidase,,,,reduced virulence,,,,,,reduced,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,RP,26134974,PubMed,10.1038/srep11831,Sci Rep. 2015 Jul 2;5:11831,yonglee@snu.ac.kr,"All seven mutants were sensitive to H2O2, suggesting that their ability to cope with oxidative stress was compromised to varying degrees.",A A Mir 2015,2015,7 genes,Mir-2015-Systematic characterization of the pe,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7150,PHI:5192,UniProt,Q3Y1R2,GenBank,HMPREF0351_12112,,,TX16 (DO),HMPREF0351_12112 (WxL locusA),,,,,,PHI:5193; PHI:5194; PHI:5195; PHI:5196,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7151,PHI:5193,UniProt,Q3Y1R1,GenBank,HMPREF0351_12113,,,TX16 (DO),HMPREF0351_12113 (WxL locusA),,,,,,PHI:5192; PHI:5194; PHI:5195; PHI:5196,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7152,PHI:5194,UniProt,Q3Y1R0,GenBank,HMPREF0351_12114,,,TX16 (DO),HMPREF0351_12114 (WxL locusA),,,,,,PHI:5192; PHI:5193; PHI:5195; PHI:5196,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7153,PHI:5195,UniProt,I3U401,GenBank,HMPREF0351_12115,,,TX16 (DO),HMPREF0351_12115 (WxL locusA),,,,,,PHI:5192; PHI:5193; PHI:5194; PHI:5196,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7154,PHI:5196,UniProt,Q3Y1Q7,GenBank,HMPREF0351_12116,,,TX16 (DO),HMPREF0351_12116 (WxL locusA),,,,,,PHI:5192; PHI:5193; PHI:5194; PHI:5195,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7155,PHI:5197,UniProt,I3TZQ0,GenBank,HMPREF0351_10614,,,TX16 (DO),HMPREF0351_10614 (WxL locusB),,,,,,PHI:5198; PHI:5199; PHI:5200,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7156,PHI:5198,UniProt,Q3XZ41,GenBank,HMPREF0351_10615,,,TX16 (DO),HMPREF0351_10615 (WxL locusB),,,,,,PHI:5197; PHI:5199; PHI:5200,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7157,PHI:5199,UniProt,Q3XZ40,GenBank,HMPREF0351_10616,,,TX16 (DO),HMPREF0351_10616 (WxL locusB),,,,,,PHI:5197; PHI:5198; PHI:5200,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7158,PHI:5200,UniProt,Q3XZ39,GenBank,HMPREF0351_10617,,,TX16 (DO),HMPREF0351_10617 (WxL locusB),,,,,,PHI:5197; PHI:5198; PHI:5199,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7159,PHI:5201,UniProt,I3TYA0,GenBank,HMPREF0351_10114,,,TX16 (DO),HMPREF0351_10114 (WxL locusC),,,,,,PHI:5202; PHI:5203; PHI:5204; PHI:5205; PHI:5206,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7160,PHI:5202,UniProt,Q3Y044,GenBank,HMPREF0351_10115,,,TX16 (DO),HMPREF0351_10115 (WxL locusC),,,,,,PHI:5201; PHI:5203; PHI:5204; PHI:5205; PHI:5206,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7161,PHI:5203,UniProt,I3TYA2,GenBank,HMPREF0351_10116,,,TX16 (DO),HMPREF0351_10116 (WxL locusC),,,,,,PHI:5201; PHI:5202; PHI:5204; PHI:5205; PHI:5206,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7162,PHI:5204,UniProt,Q3Y042,GenBank,HMPREF0351_10117,,,TX16 (DO),HMPREF0351_10117 (WxL locusC),,,,,,PHI:5201; PHI:5202; PHI:5203; PHI:5205; PHI:5206,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7163,PHI:5205,UniProt,Q3Y383,GenBank,HMPREF0351_10118,,,TX16 (DO),HMPREF0351_10118 (WxL locusC),,,,,,PHI:5201; PHI:5202; PHI:5203; PHI:5204; PHI:5206,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7164,PHI:5206,UniProt,I3TYA5,GenBank,HMPREF0351_10119,,,TX16 (DO),HMPREF0351_10119 (WxL locusC),,,,,,PHI:5201; PHI:5202; PHI:5203; PHI:5204; PHI:5205,1352,Enterococcus faecium,333849,DO,endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,involved in bile salt stress and endocarditis pathogenesis,,,,reduced virulence,,,,,,,,wild type,,no,bile salts,,,,,,gene mutation,,,RP,25512313,PubMed,10.1128/JB.02288-14,J Bacteriol. 2015 Mar;197(5):882-92,Barbara.E.Murray@uth.tmc.edu,Bile salt survival assays and animal models using a mutant from which all three WxL loci were deleted revealed the involvement of WxL operons in bile salt stress and endocarditis pathogenesis.,J R. Galloway-Peña 2014,2014,15 genes,Galloway-Pena-2014-The Identification and Func,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7165,PHI:5207,UniProt,A2I2W2,GenBank,ABL74281,,,W50,HmuY,,,,,,,837,Porphyromonas gingivalis,1403337,A7436,periodontitis,primates,9606,Homo sapiens (related: human),,,,macrophage,virulence factor of P. gingivalis for infection of macrophages in a heme-limited host environment.,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26482851,PubMed,10.1016/j.bbrc.2015.10.070,Biochem Biophys Res Commun. 2015 Nov 27;467(4):748-53,Teresa.Olczak@biotech.uni.wroc.pl,HmuY is an important virulence factor of P. Gingivalis for infection of macrophages in a heme-limited host environment.,T Olczak 2015,2015,1 gene,Olczak-2015-HmuY is an important virulence fac,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7166,PHI:5208,,no data found,,,,,,um06222,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7167,PHI:5209,,no data found,,,,,,um11763,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,esterase (xylanase),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7168,PHI:5210,,no data found,,,,,,um02239,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7169,PHI:5211,,no data found,,,,,,um05223,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,"beta-1,6-glucanase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7170,PHI:5212,,no data found,,,,,,um06127,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7171,PHI:5213,,no data found,,,,,,um01130,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,metal ion binding,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7172,PHI:5214,,no data found,,,,,,um06223,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7173,PHI:5215,UniProt,G0X7Y7,GenBank,AEK86881,,,RK124,um05311,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7174,PHI:5216,,no data found,,,,,,um01690,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7175,PHI:5217,,no data found,,,,,,um01829,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,alpha-L-arabinofuranosidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7176,PHI:5218,,no data found,,,,,,um12313,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7177,PHI:5219,UniProt,G0X7P3,GenBank,AEK86789,,,RK122,um10553,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7178,PHI:5220,UniProt,G0X7S7,GenBank,AEK86822,,,RK122,um05318,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7179,PHI:5221,UniProt,G0X809,GenBank,AEK86905,,,RK124,um05306,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7180,PHI:5222,,no data found,,,,,,um11060,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7181,PHI:5223,,no data found,,,,,,um05495,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,endoglucanase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7182,PHI:5224,,no data found,,,,,,um12217,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7183,PHI:5225,,no data found,,,,,,um03046,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7184,PHI:5226,,no data found,,,,,,um03650,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7185,PHI:5227,,no data found,,,,,,um05439,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7186,PHI:5208,,no data found,,,,,,um06222,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7187,PHI:5209,,no data found,,,,,,um11763,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,esterase (xylanase),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7188,PHI:5210,,no data found,,,,,,um02239,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7189,PHI:5211,,no data found,,,,,,um05223,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,"beta-1,6-glucanase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7190,PHI:5212,,no data found,,,,,,um06127,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7191,PHI:5213,,no data found,,,,,,um01130,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,metal ion binding,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7192,PHI:5214,,no data found,,,,,,um06223,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7193,PHI:5215,UniProt,G0X7Y7,GenBank,AEK86881,,,RK124,um05311,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7194,PHI:5216,,no data found,,,,,,um01690,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7195,PHI:5217,,no data found,,,,,,um01829,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,alpha-L-arabinofuranosidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7196,PHI:5218,,no data found,,,,,,um12313,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7197,PHI:5219,UniProt,G0X7P3,GenBank,AEK86789,,,RK122,um10553,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7198,PHI:5220,UniProt,G0X7S7,GenBank,AEK86822,,,RK122,um05318,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7199,PHI:5221,UniProt,G0X809,GenBank,AEK86905,,,RK124,um05306,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7200,PHI:5222,,no data found,,,,,,um11060,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7201,PHI:5223,,no data found,,,,,,um05495,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,endoglucanase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7202,PHI:5224,,no data found,,,,,,um12217,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7203,PHI:5225,,no data found,,,,,,um03046,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7204,PHI:5226,,no data found,,,,,,um03650,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7205,PHI:5227,,no data found,,,,,,um05439,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,tassel,chitin-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25346968,PubMed,10.1111/mpp.12133,Mol Plant Pathol. 2014 Oct;15(8):780-9,doehlemann@mpi-marburg.mpg.de,These results demonstrate that individual fungal effector proteins contribute to fungal virulence in an organ-specific manner.,L SCHILLING 2014,2014,20 genes,Schilling-2014-Virulence of the maize smut Ust,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7206,PHI:5228,UniProt,D2TV87,GenBank,WP_012908907,,,,BAHT,,,,,,,67825,Citrobacter rodentium,637910,ICC168,,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestine,heptosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25211077,PubMed,10.1016/j.chom.2014.08.008,Cell Host Microbe. 2014 Sep 10;16(3):351-63,shaofeng@nibs.ac.cn,,Q Lu 2015,2014,2 genes,Lu-2014-An iron-containing dodecameric heptosy,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7207,PHI:5299,UniProt,D2TV88,GenBank,WP_012908908,,,,CARC,,,,,,,67825,Citrobacter rodentium,637910,ICC168,,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestine,autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25211077,PubMed,10.1016/j.chom.2014.08.008,,shaofeng@nibs.ac.cn,,Q Lu 2015,2014,2 genes,Lu-2014-An iron-containing dodecameric heptosy,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7208,PHI:5230,UniProt,A3MZG1,GenBank,ABN73547,,,5b L20,Apa1,,,,,,PHI:5231,715,Actinobacillus pleuropneumoniae,416269,serotype 5b strain L20,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; kidney,trimeric autotransporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,26494209,PubMed,10.1007/s10482-015-0609-x,Antonie Van Leeuwenhoek. 2015 Oct 22,leiliancheng@163.com,,W Qin 2015,2015,2 genes,Qin-2015-Trimeric autotransporter adhesins con,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7209,PHI:5231,UniProt,A3MYH6,GenBank,ABN73212,,,5b L20,Apa2,,,,,,PHI:5230,715,Actinobacillus pleuropneumoniae,416269,serotype 5b strain L20,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; kidney,trimeric autotransporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,26494209,PubMed,10.1007/s10482-015-0609-x,Antonie Van Leeuwenhoek. 2015 Oct 22,leiliancheng@163.com,,W Qin 2015,2015,2 genes,Qin-2015-Trimeric autotransporter adhesins con,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7210,PHI:5232,UniProt,G4MTK2,GenBank,EHA55560,,,70-15,MoARG1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,arginine biosynthesis,,,arginine biosynthetic pathway,loss of pathogenicity,,yes,,,,reduced,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26505307,PubMed,10.1016/j.micres.2015.07.002,Microbiol Res. 2015 Nov;180:11-22,fuchenglin@zju.edu.cn,,Y Zhang 2015,2015,3 genes,"Zhang-2015-MoARG1, MoARG5,6 and MoARG7 involve",BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7211,PHI:5233,UniProt,G5EH72,GenBank,EAQ71018,,,70-15,"MoARG5,6",,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,arginine biosynthesis,,,arginine biosynthetic pathway,loss of pathogenicity,,yes,,,,reduced,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26505307,PubMed,10.1016/j.micres.2015.07.002,Microbiol Res. 2015 Nov;180:11-22,fuchenglin@zju.edu.cn,,Y Zhang 2015,2015,3 genes,"Zhang-2015-MoARG1, MoARG5,6 and MoARG7 involve",BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7212,PHI:5234,UniProt,A4R5F6,GenBank,EHA47241,,,70-15,MoARG7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,arginine biosynthesis,,,arginine biosynthetic pathway,reduced virulence,,yes,,,,reduced,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26505307,PubMed,10.1016/j.micres.2015.07.002,Microbiol Res. 2015 Nov;180:11-22,fuchenglin@zju.edu.cn,,Y Zhang 2015,2015,3 genes,"Zhang-2015-MoARG1, MoARG5,6 and MoARG7 involve",BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7213,PHI:5235,,no data found,GenBank,um05173,,,,Dnj1,,,,Bip1,Ensembl Genomes: um_15034,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,,,,,reduced virulence,,no,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26487566,PubMed,10.1111/nph.13703,New Phytol. 2015 Oct 21,kahmann@mpi-marburg.mpg.de,"By enabling the fungus to restore ER homeostasis and maintain a high secretory activity, Dnj1 contributes to the establishment of a compatible interaction with the host.",L L Presti 2015,2015,2 genes,Lo Presti-2015-A conserved co-chaperone is req,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7214,PHI:5236,UniProt,A0A0D2XVZ5,GenBank,KNB06105,,,4287,Dnj1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Monika,,,leaf,,,,,reduced virulence,,no,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26487566,PubMed,10.1111/nph.13703,New Phytol. 2015 Oct 21,kahmann@mpi-marburg.mpg.de,"By enabling the fungus to restore ER homeostasis and maintain a high secretory activity, Dnj1 contributes to the establishment of a compatible interaction with the host.",L L Presti 2015,2015,2 genes,Lo Presti-2015-A conserved co-chaperone is req,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7215,PHI:5237,UniProt,A0A0H3NE08,GenBank,CBW17967,,,SL1344,EcgA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26462856,PubMed,10.1111/mmi.13248,Mol Microbiol. 2015 Oct 14,fgportillo@cnb.csic.es,"EcgA production is strictly dependent on the virulence regulator PhoP in extra- and intracellular environments. Consistent to this regulation, a mutant lacking EcgA is attenuated in the mouse typhoid model.",G Rico-Pérez 2015,2015,1 gene,"Rico-Perez-2015-A novel peptidoglycan D,L-endo",BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7216,PHI:5238,UniProt,B4F053,GenBank,CAR43933,,,HI4320,RpoE,,Wild typederivative; rpoEknockout mutant; Kmr,,,,,584,Proteus mirabilis,,N2,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bladder; kidney,RNA polymerase sigma-E factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,25547796,PubMed,10.1128/IAI.02232-14,Infect Immun. 2015 Mar;83(3):966-77,sjliaw@ntu.edu.tw,"Loss of the sigma factor E (RpoE), mediating extracytoplasmic stress responses, decreased fimbria expression, survival in macrophages, cell invasion, and colonization in mice but increased the interleukin-8 (IL-8) expression of urothelial cells and swarming motility.",M Liu 2014,2014,1 gene,Liu-2014-New aspects of RpoE in Uropathogenic,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7217,PHI:5239,UniProt,Q7BM43,GenBank,AAF71499,,,DC3000,avrE,,Wild typederivative; rpoEknockout mutant; Kmr,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,DEX-inducible promoter (i.e. DEX:His:YFP:avrE),,RP,26206852,PubMed,10.1104/pp.15.00547,Plant Physiol. 2015 Sep;169(1):793-802,hes@msu.edu,,X Xin 2015,2015,1 gene,Xin-2015-Pseudomonas syringae effector AvrE lo,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7218,PHI:5240,UniProt,A0A059ZR97,GenBank,AKJ44529,,,XH386,secA,,EZ::TN<R6K>ori/KAN-2>,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,iron utilization,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25605767,PubMed,10.1128/IAI.02925-14,Infect Immun. 2015 Apr;83(4):1354-65,actisla@MiamiOH.edu,"Although some of these protein changes could negatively affect the pathobiology of the 2010 derivative, its virulence defect is mainly due to its inability to acquire iron via the acinetobactin-mediated system. These results together indicate that although the C terminus of theA. baumanniiATCC 19606T SecA is not essential for viability, it plays a critical role in the production and translocation of different proteins and virulence.",S E Fiester 2015,2015,1 gene,Fiester-2015-Role of the carboxyl terminus of,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7219,PHI:5241,,no data found,GenBank,AKI35326,,,NGAS743,SrtA,,,,,,,1314,Streptococcus pyogenes,,D471,infection,primates,9606,Homo sapiens (related: human),,,,blood; blood plasma,anchoring of virulence factors to the wall,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26484774,PubMed,10.1371/journal.pone.0140784,PLoS One. 2015 Oct 20;10(10):e0140784,araz@rockefeller.edu,"Deletion of Streptococcus pyogenessortase A leads to accumulation of sorting intermediates, particularly at the septum, altering cellular morphology and physiology, and compromising membrane integrity.",A Raz 2015,2015,1 gene,Raz-2015-Streptococcus pyogenes Sortase Mutant,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7220,PHI:5242,UniProt,A0A0H3KEX5,GenBank,BAF66913,,,Newman,ccpE,,"923 ccpE::lox66-aphAIII-lox71, Oxar, Kanr",,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,lung; skin,regulates virulence determinant biosynthesis and pathogenesis,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25193664,PubMed,10.1074/jbc.M114.584979,J Biol Chem. 2014 Oct 24;289(43):29701-11,markus.bischoff@uks.eu,Mice challenged with S. Aureus strain Newman or its isogenic ccpE derivative revealed increased disease severity in the ccpE mutant using two animal models; an acute lung infection model and a skin infection model.,T Hartmann 2014,2014,1 gene,Hartmann-2014-The Catabolite Control Protein E,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7221,PHI:5243,UniProt,G8DU30,GenBank,AEH57338,,,5428,cps14B,,,,,,,1307,Streptococcus suis,,DAN13730,meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,highly conserved regulatory gene,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25852230,PubMed,no data found,Can J Vet Res. 2015 Apr;79(2):141-6,marcelo.gottschalk@umontreal.ca,Phagocytosis assays showed high susceptibility of mutant Dcps14B. An in vivomurine model was used to demonstrate attenuated virulence of this non-encapsulated mutant.,D Roy 2015,2015,1 gene,Roy-2015-Role of the capsular polysaccharide a,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7222,PHI:5244,UniProt,D2TIS0,GenBank,CBG90830,,,ICC168,RegA,,,,,,,67825,Citrobacter rodentium,,ICC180,,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,intestine,transcriptional regulator of virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25624355,PubMed,10.1128/IAI.02697-14,Infect Immun. 2015 Apr;83(4):1384-95,r.browne@unimelb.edu.au,"RegA has been horizontally transferred to Escherichia spp. and C. rodentium. Comparative studies of two RegA homologues, namely, those fromC. rodentium and E. coli SMS-3-5, a multiresistant environmental strain of E. coli, showed that the two regulators acted similarly in vitro but differed in terms of their abilities to activate the virulence ofC. rodentium in vivo, which evidently was due to their differential activation of grlRA.",A Tan 2015,2015,1 gene,Tan-2015-Evolutionary adaptation of an AraC-li,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7223,PHI:5245,,no data found,,,,,,entD,,,,,,,1396,Bacillus cereus,226900,ATCC 14579,diarrhea; nausea; vomiting,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,an ent family exoprotein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26500610,PubMed,10.3389/fmicb.2015.01004,Front Microbiol. 2015 Oct 7;6:1004,catherine.duport@univ-avignon.fr,"The proteomic data were correlated with the growth defect, cell morphology change, reduced motility, and reduced cytotoxicity of the entD mutant strain.",H Omer 2015,2015,1 gene,Omer-2015-Proteomics identifies Bacillus cereu,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7224,PHI:5246,,no data found,GenBank,PA4704.1,,,PAO1,prrF1,,,,,,PHI:5247,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,iron-reponsive PrrF1 and PrrF2 small regulatory RNAs,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25510881,PubMed,10.1128/IAI.02707-14,Infect Immun. 2015 Mar;83(3):863-75,aoglesby@rx.umaryland.edu,"The prrF locus encoding the PrrF and PrrH sRNAs is required for P. aeruginosa virulence in a murine model of acute lung infection. Moreover, we showed that inoculation with a prrF1,2 deletion mutant protects against future challenge with wild-type P. aeruginosa.",A A Reinhart 2014,2014,2 genes,Reinhart-2014-The prrF-encoded small regulator,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7225,PHI:5247,,no data found,GenBank,PA4704.2,,,PAO1,prrF2,,,,,,PHI:5246,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,iron-reponsive PrrF1 and PrrF2 small regulatory RNAs,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25510881,PubMed,10.1128/IAI.02707-14,Infect Immun. 2015 Mar;83(3):863-75,aoglesby@rx.umaryland.edu,"The prrF locus encoding the PrrF and PrrH sRNAs is required for P. aeruginosa virulence in a murine model of acute lung infection. Moreover, we showed that inoculation with a prrF1,2 deletion mutant protects against future challenge with wild-type P. aeruginosa.",A A Reinhart 2014,2014,2 genes,Reinhart-2014-The prrF-encoded small regulator,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7226,PHI:5248,UniProt,Q8L360,GenBank,AF390107_4,,,O90R,RgfC,,,,,,PHI:5249,1311,Streptococcus agalactiae,205921,A909,postpartum infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; brain,sensor histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25561709,PubMed,10.1128/IAI.02738-14,Infect Immun. 2015 Mar;83(3):1078-88,lakshmi.rajagopal@seattlechildrens.org,"Deletion ofrgfC in GBS strains lacking a functional RgfA increased systemic infection. Furthermore, infection with the rgfC mutant increased induction of proinflammatory signaling pathways in vivo.",C Gendrin 2015,2015,2 genes,Gendrin-2015-The sensor histidine kinase RgfC,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7227,PHI:5249,UniProt,Q8L361,GenBank,AF390107_3,,,O90R,RgfA,,,,,,PHI:5248,1311,Streptococcus agalactiae,205921,A909,postpartum infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; brain,response regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25561709,PubMed,10.1128/IAI.02738-14,Infect Immun. 2015 Mar;83(3):1078-88,lakshmi.rajagopal@seattlechildrens.org,"Deletion ofrgfC in GBS strains lacking a functional RgfA increased systemic infection. Furthermore, infection with the rgfC mutant increased induction of proinflammatory signaling pathways in vivo.",C Gendrin 2015,2015,2 genes,Gendrin-2015-The sensor histidine kinase RgfC,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7228,PHI:5250,UniProt,A0A0F7R1R1,GenBank,AKZ25194,,,YC45,lecM,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf; root; stem,mannose-fucose binding lectin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26445498,PubMed,10.1371/journal.pone.0139090,PLoS One. 2015 Oct 7;10(10):e0139090,cza@plantpath.wisc.edu,"Mutants lacking lecM, aidA,or aidC were each significantly more reduced in virulence on tomato at 20°C than at 28°C in both a naturalistic soil soak inoculation assay and when they were inoculated directly into tomato stems.",F Meng 2015,2015,3 genes,Meng-2015-Comparative Transcriptome Analysis R,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7229,PHI:5251,UniProt,A3RTU4,GenBank,EAP73005,,,UW551,aidA,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf; root; stem,quorum sensing-dependent protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26445498,PubMed,10.1371/journal.pone.0139090,PLoS One. 2015 Oct 7;10(10):e0139090,cza@plantpath.wisc.edu,"Mutants lacking lecM, aidA,or aidC were each significantly more reduced in virulence on tomato at 20°C than at 28°C in both a naturalistic soil soak inoculation assay and when they were inoculated directly into tomato stems.",F Meng 2015,2015,3 genes,Meng-2015-Comparative Transcriptome Analysis R,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7230,PHI:5252,,no data found,,,,,UW551,aidC,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf; root; stem,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26445498,PubMed,10.1371/journal.pone.0139090,PLoS One. 2015 Oct 7;10(10):e0139090,cza@plantpath.wisc.edu,"Mutants lacking lecM, aidA,or aidC were each significantly more reduced in virulence on tomato at 20°C than at 28°C in both a naturalistic soil soak inoculation assay and when they were inoculated directly into tomato stems.",F Meng 2015,2015,3 genes,Meng-2015-Comparative Transcriptome Analysis R,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7231,PHI:5253,UniProt,I1S5P3,GenBank,ESU08050,,,PH-1,FgSge1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 19,,,spike,transcription factor,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,H2O2; Congo red; NaCl; KCl,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene mutation: characterised,,,RP,26130440,PubMed,10.1007/s11274-015-1894-2,World J Microbiol Biotechnol. 2015 Sep;31(9):1419-30,ynyin@zju.edu.cn,Mutants containing a T67A mutation within the potential protein kinase A (Pka) phosphorylation site of FgSge1 exhibited a significant decrease in conidiation and dramatically impaired virulence on both wheat head and nonhost tomato.,F Yu 2015,2015,1 gene,Yu-2015-The potential protein kinase A (Pka) p,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7232,PHI:5253,UniProt,I1S5P3,GenBank,ESU08050,,,PH-1,FgSge1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 19,,,spike,transcription factor,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,H2O2; Congo red; NaCl; KCl,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full,,,RP,26130440,PubMed,10.1007/s11274-015-1894-2,World J Microbiol Biotechnol. 2015 Sep;31(9):1419-30,ynyin@zju.edu.cn,Mutants containing a T67A mutation within the potential protein kinase A (Pka) phosphorylation site of FgSge1 exhibited a significant decrease in conidiation and dramatically impaired virulence on both wheat head and nonhost tomato.,F Yu 2015,2015,1 gene,Yu-2015-The potential protein kinase A (Pka) p,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7233,PHI:5253,UniProt,I1S5P3,GenBank,ESU08050,,,PH-1,FgSge1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,transcription factor,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,H2O2; Congo red; NaCl; KCl,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene mutation: characterised,,,RP,26130440,PubMed,10.1007/s11274-015-1894-2,World J Microbiol Biotechnol. 2015 Sep;31(9):1419-30,ynyin@zju.edu.cn,Mutants containing a T67A mutation within the potential protein kinase A (Pka) phosphorylation site of FgSge1 exhibited a significant decrease in conidiation and dramatically impaired virulence on both wheat head and nonhost tomato.,F Yu 2015,2015,1 gene,Yu-2015-The potential protein kinase A (Pka) p,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7234,PHI:5253,UniProt,I1S5P3,GenBank,ESU08050,,,PH-1,FgSge1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,transcription factor,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,H2O2; Congo red; NaCl; KCl,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full,,,RP,26130440,PubMed,10.1007/s11274-015-1894-2,World J Microbiol Biotechnol. 2015 Sep;31(9):1419-30,ynyin@zju.edu.cn,Mutants containing a T67A mutation within the potential protein kinase A (Pka) phosphorylation site of FgSge1 exhibited a significant decrease in conidiation and dramatically impaired virulence on both wheat head and nonhost tomato.,F Yu 2015,2015,1 gene,Yu-2015-The potential protein kinase A (Pka) p,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7235,PHI:5255,UniProt,P0DJP3,GenBank,CAJ01897,,,SLCC7509,secA2,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,spleen; liver,protein translocase subunit SecA,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation,,,RP,25535272,PubMed,10.1128/JB.02284-14,J Bacteriol. 2015 Mar;197(5):932-42,portnoy@berkeley.edu,"A point mutation in secY was identified that conferred smooth colony morphology to secA2 mutants, restored wild-type plaque formation, and increased virulence in mice.",J Durack 2014,2014,3 genes,Durack-2014-A prl mutation in SecY suppresses,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7236,PHI:5256,UniProt,Q8Y6G6,GenBank,CAC99799,,,EGD-e,LacR,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,spleen; liver,sigma-54 interaction domaincontaining protein,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation,,,RP,25535272,PubMed,10.1128/JB.02284-14,J Bacteriol. 2015 Mar;197(5):932-42,portnoy@berkeley.edu,"A point mutation in secY was identified that conferred smooth colony morphology to secA2 mutants, restored wild-type plaque formation, and increased virulence in mice.",J Durack 2014,2014,3 genes,Durack-2014-A prl mutation in SecY suppresses,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7237,PHI:5257,UniProt,Q8Y448,GenBank,CAD00690,,,EGD-e,secY,,,,,,PHI:5355,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,spleen; liver,protein translocase subunit SecY,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25535272,PubMed,10.1128/JB.02284-14,J Bacteriol. 2015 Mar;197(5):932-42,portnoy@berkeley.edu,"A point mutation in secY was identified that conferred smooth colony morphology to secA2 mutants, restored wild-type plaque formation, and increased virulence in mice.",J Durack 2014,2014,3 genes,Durack-2014-A prl mutation in SecY suppresses,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7238,PHI:5255,UniProt,P0DJP3,GenBank,CAJ01897,,,SLCC7509,secA2,,,,,,PHI:5357,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,spleen; liver,protein translocase subunit SecA,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25535272,PubMed,10.1128/JB.02284-14,J Bacteriol. 2015 Mar;197(5):932-42,portnoy@berkeley.edu,"A point mutation in secY was identified that conferred smooth colony morphology to secA2 mutants, restored wild-type plaque formation, and increased virulence in mice.",J Durack 2014,2014,3 genes,Durack-2014-A prl mutation in SecY suppresses,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7239,PHI:5257,UniProt,Q8Y448,GenBank,CAD00690,,,EGD-e,secY,,,,,,PHI:5356,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,spleen; liver,protein translocase subunit SecY,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25535272,PubMed,10.1128/JB.02284-14,J Bacteriol. 2015 Mar;197(5):932-42,portnoy@berkeley.edu,"A point mutation in secY was identified that conferred smooth colony morphology to secA2 mutants, restored wild-type plaque formation, and increased virulence in mice.",J Durack 2014,2014,3 genes,Durack-2014-A prl mutation in SecY suppresses,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7240,PHI:5256,UniProt,Q8Y6G6,GenBank,CAC99799,,,EGD-e,LacR,,,,,,PHI:5357,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,spleen; liver,sigma-54 interaction domaincontaining protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25535272,PubMed,10.1128/JB.02284-14,J Bacteriol. 2015 Mar;197(5):932-42,portnoy@berkeley.edu,"A point mutation in secY was identified that conferred smooth colony morphology to secA2 mutants, restored wild-type plaque formation, and increased virulence in mice.",J Durack 2014,2014,3 genes,Durack-2014-A prl mutation in SecY suppresses,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7241,PHI:5258,UniProt,Q8KQ33,GenBank,AAM52058,,,PA131533,tfpO,,,,,,,287,Pseudomonas aeruginosa,,1244,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,lung,glycosyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25605768,PubMed,10.1128/IAI.02874-14,Infect Immun. 2015 Apr;83(4):1339-46,geelau@illinois.edu,"Using an acute pneumonia model in SP-A+/+ versus SP-A -/- mice, the O-glycosylation-deficient tfpO mutant was found to be attenuated in lung infection.",R M Tan 2015,2015,1 gene,Tan-2015-Type IV Pilus Glycosylation Mediates,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7242,PHI:5259,UniProt,I1REJ4,GenBank,ESU07473,,,PH-1,FgArt1,chromosome 1,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,A Zn(II)2Cys6 zinc finger transcription factor,,,,reduced virulence,,,,yes,,,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26456718,PubMed,10.1111/mpp.12328,Mol Plant Pathol. 2015 Oct 12,hunkim@krict.re.kr,,M OH 2015,2015,1 gene,Oh-2015-Transcription Factor ART1 Mediates Sta,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7243,PHI:5260,UniProt,A0A031WJD5,GenBank,CEK00177,,,630Derm,GerS,chromosome 1,JIR8094gerS::ermB,,,,,1496,Clostridioides difficile,,JIR8094,enteric disease,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,regulator of spore germination,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26496694,PubMed,10.1371/journal.ppat.1005239,PLoS Pathog. 2015 Oct 23;11(10):e1005239,aimee.shen@uvm.edu,Pathogen formerly called Clostridium difficile,K A Fimlaid 2015,2015,1 gene,Fimlaid-2015-Identification of a Novel Lipopro,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7244,PHI:5261,,no data found,,,,,WK-1C,CmNPS3,,,,,,,101162,Bipolaris oryzae,930090,WK-1C,brown spot,monocots,4530,Oryza sativa (related: rice),,,,leaf,tentoxin production,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26456797,PubMed,10.1111/mpp.12329,Mol Plant Pathol. 2015 Oct 12,monica.hofte@ugent.be,Infection tests with wild type and Cmnps3mutants showed that tentoxin acts as a virulence factor and is correlated with chlorosis development during the second phase of infection.,L D Bruyne 2015,2015,1 gene,De Bruyne-2015-Comparative chemical screening,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7245,PHI:5262,UniProt,Q8FDW4,GenBank,AF289092_1,,,CFT073,Sat,,sat::cat,,,,,562,Escherichia coli,,Nissle 1917,non-pathogenic: probiotic,rodents,10090,Mus musculus (related: house mouse),CD-1,,,bladder; kidney,auto transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26518156,PubMed,10.1186/s12866-015-0591-5,BMC Microbiol. 2015 Oct 30;15(1):250,lbaldoma@ub.edu,Escherichia coliNissle 1917 (EcN) is a probiotic used in the treatment of intestinal diseases. Sat does not act as a virulence factor in EcN. The role of Sat in intestinal pathogenesis relies on other genetic determinants responsible for the bacterial pathotype.,L Toloza 2015,2015,1 gene,Toloza-2015-The secreted autotransporter toxin,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7246,PHI:5263,UniProt,Q9I1B8,GenBank,AE004662_4,,,PAO1,icmF3,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,intracellular multiplication factor (IcmF) protein,,,,reduced virulence,yes,,,,,,,aberrant; increased,,no,tobramycin; gentamicin,tobramycin: CHEBI:28864; gentamicin: CHEBI:17833,,,,,gene deletion: full; gene complementation,,,RP,26484316,PubMed,10.3389/fcimb.2015.00070,Front Cell Infect Microbiol. 2015 Oct 1;5:70,xihuishen@nwsuaf.edu.cn,The mutant exhibits decreased susceptibility to aminoglycosides such as tobramycin and gentamicin.,J Lin 2015,2015,1 gene,Lin-2015-The icmF3 locus is involved in multip,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7247,PHI:5264,UniProt,Q5X9A9,GenBank,AAA17981,,,S43,hasA,,,,,,,1314,Streptococcus pyogenes,,MGAS23530,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,muscle,hyaluronan synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26443457,PubMed,10.1128/mBio.01378-15,MBio. 2015 Oct 6;6(5):e01378-15,jmmusser@houstonmethodist.org,"Emm89strains with elevated toxin production are significantly more virulent than low-toxin producers. Importantly, we also show that capsule production is dispensable for virulence in strains that already produce high levels of SPN and SLO.",L Zhu 2015,2015,3 genes,Zhu-2015-Trading Capsule for Increased Cytotox,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7248,PHI:5265,UniProt,Q9RF14,GenBank,AF203370_1,,,96-004,nga,,,,,,,1314,Streptococcus pyogenes,,MGAS23530,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,muscle,nicotine adenine dinucleotide glycohydrolase precursor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26443457,PubMed,10.1128/mBio.01378-15,MBio. 2015 Oct 6;6(5):e01378-15,jmmusser@houstonmethodist.org,"Emm89strains with elevated toxin production are significantly more virulent than low-toxin producers. Importantly, we also show that capsule production is dispensable for virulence in strains that already produce high levels of SPN and SLO.",L Zhu 2015,2015,3 genes,Zhu-2015-Trading Capsule for Increased Cytotox,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7249,PHI:5266,UniProt,P0C0I3,GenBank,AAK33267,,,SF370,slo,,,,,,,1314,Streptococcus pyogenes,,MGAS23530,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,muscle,streptolysin O,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26443457,PubMed,10.1128/mBio.01378-15,MBio. 2015 Oct 6;6(5):e01378-15,jmmusser@houstonmethodist.org,"Emm89strains with elevated toxin production are significantly more virulent than low-toxin producers. Importantly, we also show that capsule production is dispensable for virulence in strains that already produce high levels of SPN and SLO.",L Zhu 2015,2015,3 genes,Zhu-2015-Trading Capsule for Increased Cytotox,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7250,PHI:5267,UniProt,E9R863,GenBank,AAY42823,,,YJ-407,UgeB,,,,,,,162425,Aspergillus nidulans,,A26,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,epimerase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26492565,PubMed,10.1371/journal.ppat.1005187,PLoS Pathog. 2015 Oct 22;11(10):e1005187,don.sheppard@mcgill.ca,"Increasing the GalNAc content of GAG of the minimally pathogenic A.nidulans, either through overexpression of the A. nidulans epimerase UgeB or by heterologous expression of the A.fumigatus epimerase Uge3 increased the amount of cell wall bound GAG, augmented adherencein vitro and enhanced virulence in corticosteroid-treated mice to levels similar to A.fumigatus.",M J Lee 2015,2015,2 genes,Lee-2015-The Fungal Exopolysaccharide Galactos,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7251,PHI:5268,UniProt,C8V0N8,GenBank,CBF69548,,,FGSC A4,Uge3,,,,,,,162425,Aspergillus nidulans,,A26,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,epimerase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26492565,PubMed,10.1371/journal.ppat.1005187,PLoS Pathog. 2015 Oct 22;11(10):e1005187,don.sheppard@mcgill.ca,"Increasing the GalNAc content of GAG of the minimally pathogenic A.nidulans, either through overexpression of the A. nidulans epimerase UgeB or by heterologous expression of the A.fumigatus epimerase Uge3 increased the amount of cell wall bound GAG, augmented adherencein vitro and enhanced virulence in corticosteroid-treated mice to levels similar to A.fumigatus.",M J Lee 2015,2015,2 genes,Lee-2015-The Fungal Exopolysaccharide Galactos,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7252,PHI:5270,UniProt,W7MFP3,GenBank,EWG43587,,,7600,FvBck1,chromosome 4,,,,,,117187,Fusarium verticillioides,334819,7600,pokkah boeng,monocots,4547,Saccharum officinarum (related: sugarcane),cv. Heiganzhe,,,stem,MAP kinase kinase kinase,,,MAP kinase pathway,reduced virulence,,,,,,reduced,,reduced,,no,H202; calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); NaCl; sorbitol,H2O2: CHEBI:16240; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26500635,PubMed,10.3389/fmicb.2015.01096,Front Microbiol. 2015 Oct 8;6:1096,gdlufafu@163.com,"FvBCK1 is not only required for growth, micro- and macro-conidia production, and cell wall integrity but also for response to osmotic and oxidative stresses. The deletion of FvBCK1 caused a significant reduction in virulence and FB1 production",C Zhang 2015,2015,1 gene,"Zhang-2015-FvBck1, a component of cell wall in",BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7253,PHI:5271,UniProt,Q8Y0J2,GenBank,CAD14754,,,GMI1000,fabG1,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,3-ketoacyl-acyl carrier protein reductase,,,fatty acid synthetic pathways,lethal,,,,,,,,,,yes,,,,,,,gene disruption; gene complementation,,,RP,26490537,PubMed,10.1186/s12866-015-0554-x,BMC Microbiol. 2015 Oct 22;15(1):223,wanghh36@scau.edu.cn,"RsfabG1 gene carried on the R. solanacearum chromosome is essential for growth of the bacterium, as is the case for fabG in E. coli. In contrast, the null mutant strain with the megaplasmid-encoded RsfabG2 gene is viable but has a fatty acid composition that differs significantly from that of the wild type strain. Our study also shows that RsFabG2 plays a role in adaptation to high salt concentration and low pH, and in pathogenesis of disease in tomato plants.",S Feng 2015,2015,2 genes,Feng-2015-Ralstonia solanacearum fatty acid co,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7254,PHI:5272,UniProt,Q8XSV8,GenBank,CAD17510,,,GMI1000,fabG2,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,,3-ketoacyl-acyl carrier protein reductase,,,fatty acid synthetic pathways,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene disruption; gene complementation,,,RP,26490537,PubMed,10.1186/s12866-015-0554-x,BMC Microbiol. 2015 Oct 22;15(1):223,wanghh36@scau.edu.cn,"RsfabG1 gene carried on the R. solanacearum chromosome is essential for growth of the bacterium, as is the case for fabG in E. coli. In contrast, the null mutant strain with the megaplasmid-encoded RsfabG2 gene is viable but has a fatty acid composition that differs significantly from that of the wild type strain. Our study also shows that RsFabG2 plays a role in adaptation to high salt concentration and low pH, and in pathogenesis of disease in tomato plants.",S Feng 2015,2015,2 genes,Feng-2015-Ralstonia solanacearum fatty acid co,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7255,PHI:5273,,no data found,GenBank,srn3610,,,,SprC,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),SWR,,,kidney,regulatory RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26240382,PubMed,10.1093/nar/gkv783,Nucleic Acids Res. 2015 Oct 30;43(19):9232-48,bFelden@univ-rennes1.fr,"S. aureus sRNA, SprC (srn3610), reduced virulence and bacterial loads in a mouse infection model. S. aureus deleted for sprC became more virulent and increased bacterial dissemination in colonized animals. Conversely, inducing SprC expression lowered virulence and the bacterial load.",H L Pabic 2015,2015,1 gene,Le Pabic-2015-A bacterial regulatory RNA atten,BATCH_054,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7256,PHI:5274,,no data found,GenBank,ADV88039,,,MO6-24/O,VVMO6_03017,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,cFP production,,,NF- B pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25561711,PubMed,10.1128/IAI.02878-14,Infect Immun. 2015 Mar;83(3):1150-61,grlee@sogang.ac.kr,A deletion of VVMO6_03017 diminished cFP production and decreased virulence in subcutaneously inoculated mice.,K Kim 2015,2015,1 gene,Kim-2015-Cyclo(Phe-Pro) produced by the human,BATCH_054B,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7257,PHI:5275,UniProt,B7VKI8,GenBank,CAV17749,,,LGP32,copA,,,,,,,212663,Vibrio tasmaniensis,575788,LGP32,,bivalves,29159,Crassostrea gigas (related: pacific oyster),,,,,copper homeostasis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26472275,PubMed,10.1111/1462-2920.13083,Environ Microbiol. 2015 Oct 16,ddestoum@ifremer.fr,,A S Vanhove 2015,2015,1 gene,Vanhove-2015-Copper homeostasis at the host vi,BATCH_054B,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7258,PHI:5276,UniProt,G1XU04,GenBank,EGX43547,,,ATCC 24927,AOL_s00215g283,,,,,,,2813651,Orbilia oligospora,,YMF 1.3170,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,polyketide synthase gene,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,26422178,PubMed,10.1021/acs.jafc.5b04244,J Agric Food Chem. 2015 Oct 21;63(41):9076-82,xmniu@ynu.edu.cn,"The mutant strain displayed significant increases in the trap formation and the nematicidal activity by 10 and 2 times, respectively, higher than the wild-type strain. Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.",Z Xu 2015,2015,1 gene,Xu-2015-High Trap Formation and Low Metabolite,BATCH_054B,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7259,PHI:5277,UniProt,S8F6T7,GenBank,EPT30417,,,ME49,ASP5,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,aaspartyl protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,26473595,PubMed,10.1371/journal.ppat.1005211,PLoS Pathog. 2015 Oct 16;11(10):e1005211,dominique.soldati-favre@unige.ch,Deletion of ASP5 causes a significant loss in parasite fitnessin vitro and an altered virulencein vivo.,P Hammoudi 2015,2015,1 gene,Hammoudi-2015-Fundamental Roles of the Golgi-A,BATCH_054B,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7260,PHI:5278,UniProt,O34208,GenBank,AAC16023,,,PA103,ExoU,,,,,,,287,Pseudomonas aeruginosa,,PA4,nosocomial infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,type III toxin with phospholipase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,16882033,PubMed,10.1111/j.1462-5822.2006.00710.x,Cell Microbiol. 2006 Aug;8(8):1294-309,t.j.evans@udcf.gla.ac.uk,Site-directed mutagenesis identified a tryptophan at position 681 as crucial for these effects. We found that the same region at position 679-683 was also required for cell toxicity produced by ExoU as well as in vitro phospholipase activity.,F R Stirling 2006,2006,1 gene,"Stirling-2006-Eukaryotic localization, activat",BATCH_054B,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7261,PHI:5279,UniProt,Q6RKI7,GenBank,AAR90249,,,B05.10,Bcpks13,chromosome 3,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,DHN melanin biosynthesis,,,,unaffected pathogenicity,,,,,,aberrant,wild type,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26514268,PubMed,10.1111/mmi.13262,Mol Microbiol. 2015 Oct 30,Julia.schumacher@wwu.de,"Melanogenic genes are dispensable in vegetative mycelia for proper growth and virulence. However, DHN melanin is considered to contribute to the longevity of the reproduction structures.",,2015,2 genes,Schumacher-2015-DHN melanin biosynthesis in th,BATCH_054B,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7262,PHI:5280,UniProt,Q6RKI8,GenBank,AAR90248,,,B05.10,Bcpks12,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,DHN melanin biosynthesis,,,,unaffected pathogenicity,,,,,,wild type,aberrant,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26514268,PubMed,10.1111/mmi.13262,Mol Microbiol. 2015 Oct 30,Julia.schumacher@wwu.de,"Melanogenic genes are dispensable in vegetative mycelia for proper growth and virulence. However, DHN melanin is considered to contribute to the longevity of the reproduction structures.",,2015,2 genes,Schumacher-2015-DHN melanin biosynthesis in th,BATCH_054B,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7263,PHI:5281,UniProt,D4HVM9,GenBank,CBA19486,,,CFBP1430,hrpL,,,,HrpS,UniProt: D4HVN2,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,regulation of the type III secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,26440313,PubMed,10.1111/mpp.12324,Mol Plant Pathol. 2015 Oct 6,zhao888@illinois.edu,,J H Lee 2015,2015,1 genes,Lee-2015-Identification of the HrpS binding si,BATCH_054B,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7264,PHI:5281,UniProt,D4HVM9,GenBank,CBA19486,,,CFBP1430,hrpL,,,,HrpS,UniProt: D4HVN2,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),cv. Bartlett,,,fruit,regulation of the type III secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,26440313,PubMed,10.1111/mpp.12324,Mol Plant Pathol. 2015 Oct 6,zhao888@illinois.edu,,J H Lee 2015,2015,1 genes,Lee-2015-Identification of the HrpS binding si,BATCH_054B,2015-11-01,MC,,,,,,,,,,,,,
,,Record 7265,PHI:5282,UniProt,Q59VF4,GenBank,EAK94484,,,SC5314,Hat1,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,acetyltransferase,,,,reduced virulence,,,,,,,,,,no,calcofluor white; Congo red; NaCl; tert-butyl hydroperoxide (tBOOH); diamide; CdCl2; voriconazole; itraconazole; amphotericin B,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; NaCl: CHEBI:26710; tert-butyl hydroperoxide (tBOOH): CHEBI:64090; CdCl2: CHEBI:35456; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; amphotericin B: CHEBI:2682,,,,,gene mutation,,,RP,26473952,PubMed,10.1371/journal.ppat.1005218,PLoS Pathog. 2015 Oct 16;11(10):e1005218,karl.kuchler@meduniwien.ac.at,Clearance from infected mice is delayed although cells lacking Hat1 are severely compromised in killing the host.,M Tscherner 2015,2015,1 gene,Tscherner-2015-The Candida albicans Histone Ac,BATCH_054B,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7266,PHI:5283,UniProt,Q2A0P1,GenBank,CAJ83999,,,,AVR2,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain Fol007,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. C32,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,26583031,PubMed,10.3389/fpls.2015.00967,Front Plant Sci. 2015 Nov 4;6:967,f.l.w.takken@uva.nl,,F Gawehns 2015,2015,5 genes,Gawehns-2015-The effector repertoire of determ,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7267,PHI:5284,UniProt,Q709D8,GenBank,CAE55870,,,,AVR3,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain Fol007,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. C32,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,26583031,PubMed,10.3389/fpls.2015.00967,Front Plant Sci. 2015 Nov 4;6:967,f.l.w.takken@uva.nl,,F Gawehns 2015,2015,5 genes,Gawehns-2015-The effector repertoire of determ,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7268,PHI:5285,UniProt,Q709E0,GenBank,ACY39282,,,BFOL-51,SIX2,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain Fol007,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. C32,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,26583031,PubMed,10.3389/fpls.2015.00967,Front Plant Sci. 2015 Nov 4;6:967,f.l.w.takken@uva.nl,,F Gawehns 2015,2015,5 genes,Gawehns-2015-The effector repertoire of determ,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7269,PHI:5286,UniProt,C0LT61,GenBank,ACN87967,,,,SIX5,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain Fol007,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. C32,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,26583031,PubMed,10.3389/fpls.2015.00967,Front Plant Sci. 2015 Nov 4;6:967,f.l.w.takken@uva.nl,,F Gawehns 2015,2015,5 genes,Gawehns-2015-The effector repertoire of determ,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7270,PHI:5287,UniProt,C9WMG8,GenBank,ACN69116,,,,SIX6,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain Fol007,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. C32,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,RP,26583031,PubMed,10.3389/fpls.2015.00967,Front Plant Sci. 2015 Nov 4;6:967,f.l.w.takken@uva.nl,,F Gawehns 2015,2015,5 genes,Gawehns-2015-The effector repertoire of determ,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7271,PHI:5288,UniProt,P9WIB5,GenBank,AAC18943,,,H37Rv,plcA,,,,,,PHI:5289; PHI:5290,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,phospholipases C,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26603639,PubMed,10.1038/srep16918,Sci Rep. 2015 Nov 25;5:16918,roland.brosch@pasteur.fr,,F L Chevalier 2015,2015,3 genes,Le Chevalier-2015-Revisiting the role of phosp,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7272,PHI:5289,UniProt,P9WIB3,GenBank,AAC18944,,,H37Rv,plcB,,,,,,PHI:5288; PHI:5290,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,phospholipases C,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26603639,PubMed,10.1038/srep16918,Sci Rep. 2015 Nov 25;5:16918,roland.brosch@pasteur.fr,,F L Chevalier 2015,2015,3 genes,Le Chevalier-2015-Revisiting the role of phosp,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7273,PHI:5290,UniProt,P9WIB1,GenBank,CCP45137,,,H37Rv,plcC,,,,,,PHI:5288; PHI:5289,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,phospholipases C,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26603639,PubMed,10.1038/srep16918,Sci Rep. 2015 Nov 25;5:16918,roland.brosch@pasteur.fr,,F L Chevalier 2015,2015,3 genes,Le Chevalier-2015-Revisiting the role of phosp,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7274,PHI:5291,,no data found,GenBank,ALM04117,,,,pacC,,,,,,,35717,Epichloe festucae,877507,Fl1,,monocots,4522,Lolium perenne (related: perennial ryegrass),,,,leaf,pH response transcription factor,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full,,,RP,26529380,PubMed,10.1016/j.fgb.2015.10.008,Fungal Genet Biol. 2015 Dec;85:25-37,d.b.scott@massey.ac.nz,Alkaline pH was observed to induce conidiation in wild-type E. festucae but not in the DpacC mutant. On the other hand the pacCC mutant had increased conidiation at neutral pH alone. NullpacCmutants had no effect on the symbiotic interaction with ryegrass plants whereas the pacCC mutant increased the tiller number.,Y Lukito 2015,2015,1 gene,Lukito-2015-Molecular and cellular analysis of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7275,PHI:5291,,no data found,GenBank,ALM04117,,,,pacC,,,,,,,35717,Epichloe festucae,877507,Fl1,,monocots,4522,Lolium perenne (related: perennial ryegrass),,,,leaf,pH response transcription factor,,,,increased virulence (hypervirulence),,,,,,increased,,aberrant,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26529380,PubMed,10.1016/j.fgb.2015.10.008,Fungal Genet Biol. 2015 Dec;85:25-37,d.b.scott@massey.ac.nz,Alkaline pH was observed to induce conidiation in wild-type E. festucae but not in the DpacC mutant. On the other hand the pacCC mutant had increased conidiation at neutral pH alone. NullpacCmutants had no effect on the symbiotic interaction with ryegrass plants whereas the pacCC mutant increased the tiller number.,Y Lukito 2015,2015,1 gene,Lukito-2015-Molecular and cellular analysis of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7276,PHI:5292,UniProt,A0A0F7R1R1,GenBank,AKZ25194,,,YC45,lecM,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf; root,"encoding a lectin, RS-IIL",,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,26609568,PubMed,10.1111/mpp.12335,Mol Plant Pathol. 2015 Nov 26,yhikichi@kochi-u.ac.jp,"Colonization in intercellular spaces was significantly decreased inthe lecMmutant, leading to a loss of its virulence on tomato plants.",Y Mori 2015,2015,1 gene,Mori-2015-The vascular plant pathogenic bacter,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7277,PHI:5293,UniProt,B4EHX2,GenBank,CAR55188,,,J2315,BCAM1331,,,,,,PHI:5294,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,tyrosine kinases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26590274,PubMed,10.1128/AEM.03513-15,Appl Environ Microbiol. 2015 Nov 20. pii: AEM.03513-15,m.valvano@qub.ac.uk,"BCAM1331, BceF, BCAM0208 and BceD contributed to biofilm formation, while BCAL2200 was required for growth in nutrient-limited conditions. Multiple deletions of either tyrosine kinase or low molecular weightprotein tyrosine phosphatases genes resulted in attenuation of B. cenocepacia intramacrophage survival and reduced pathogenicity in the Galleria mellonella larvae infection model.",A Andrade 2015,2015,5 genes,Andrade-2015-Tyrosine phosphorylation and deph,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7278,PHI:5294,UniProt,B4EMX8,GenBank,CAR54717,,,J2315,BceF,,,,,,PHI:5293,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,tyrosine kinases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26590274,PubMed,10.1128/AEM.03513-15,Appl Environ Microbiol. 2015 Nov 20. pii: AEM.03513-15,m.valvano@qub.ac.uk,"BCAM1331, BceF, BCAM0208 and BceD contributed to biofilm formation, while BCAL2200 was required for growth in nutrient-limited conditions. Multiple deletions of either tyrosine kinase or low molecular weightprotein tyrosine phosphatases genes resulted in attenuation of B. cenocepacia intramacrophage survival and reduced pathogenicity in the Galleria mellonella larvae infection model.",A Andrade 2015,2015,5 genes,Andrade-2015-Tyrosine phosphorylation and deph,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7279,PHI:5295,UniProt,B4EHP0,GenBank,CAR54066,,,J2315,BCAM0208,,,,,,PHI:5296; PHI:5297,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,protein tyrosine phosphatases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26590274,PubMed,10.1128/AEM.03513-15,Appl Environ Microbiol. 2015 Nov 20. pii: AEM.03513-15,m.valvano@qub.ac.uk,"BCAM1331, BceF, BCAM0208 and BceD contributed to biofilm formation, while BCAL2200 was required for growth in nutrient-limited conditions. Multiple deletions of either tyrosine kinase or low molecular weightprotein tyrosine phosphatases genes resulted in attenuation of B. cenocepacia intramacrophage survival and reduced pathogenicity in the Galleria mellonella larvae infection model.",A Andrade 2015,2015,5 genes,Andrade-2015-Tyrosine phosphorylation and deph,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7280,PHI:5296,UniProt,B4EMX6,GenBank,CAR54715,,,J2315,BceD,,,,,,PHI:5295; PHI:5297,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,protein tyrosine phosphatases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26590274,PubMed,10.1128/AEM.03513-15,Appl Environ Microbiol. 2015 Nov 20. pii: AEM.03513-15,m.valvano@qub.ac.uk,"BCAM1331, BceF, BCAM0208 and BceD contributed to biofilm formation, while BCAL2200 was required for growth in nutrient-limited conditions. Multiple deletions of either tyrosine kinase or low molecular weightprotein tyrosine phosphatases genes resulted in attenuation of B. cenocepacia intramacrophage survival and reduced pathogenicity in the Galleria mellonella larvae infection model.",A Andrade 2015,2015,5 genes,Andrade-2015-Tyrosine phosphorylation and deph,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7281,PHI:5297,UniProt,B4EDS9,GenBank,CAR52501,,,J2315,BCAL2200,,,,,,PHI:5295; PHI:5296,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,protein tyrosine phosphatases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26590274,PubMed,10.1128/AEM.03513-15,Appl Environ Microbiol. 2015 Nov 20. pii: AEM.03513-15,m.valvano@qub.ac.uk,"BCAM1331, BceF, BCAM0208 and BceD contributed to biofilm formation, while BCAL2200 was required for growth in nutrient-limited conditions. Multiple deletions of either tyrosine kinase or low molecular weightprotein tyrosine phosphatases genes resulted in attenuation of B. cenocepacia intramacrophage survival and reduced pathogenicity in the Galleria mellonella larvae infection model.",A Andrade 2015,2015,5 genes,Andrade-2015-Tyrosine phosphorylation and deph,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7282,PHI:5298,UniProt,Q9I7B5,GenBank,AE004441_2,,,PAO1,PA0011,,"PA0011 replacement mutant with a Ω-Sm cassette inserted, SmR",,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,2-OH-lauroytransferase,,,,reduced virulence,,,,,,,,,,no,carbapenems,carbapenems: CHEBI:46633,,,,,gene deletion: full; gene complementation,,,RP,26596709,PubMed,10.1016/j.micpath.2015.11.003,Microb Pathog. 2015 Nov 17. pii: S0882-4010(15)00175-8,shenlx@nwu.edu.cn,,B Wang 2015,2015,1 gene,Wang-2015-Pleiotropic effects of temperature-r,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7283,PHI:5298,UniProt,Q9I7B5,GenBank,AE004441_2,,,PAO1,PA0011,,"PA0011 replacement mutant with a Ω-Sm cassette inserted, SmR",,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,2-OH-lauroytransferase,,,,reduced virulence,,,,,,,,,,no,carbapenems,carbapenems: CHEBI:46633,,,,,gene deletion: full; gene complementation,,,RP,26596709,PubMed,10.1016/j.micpath.2015.11.003,Microb Pathog. 2015 Nov 17. pii: S0882-4010(15)00175-8,shenlx@nwu.edu.cn,,B Wang 2015,2015,1 gene,Wang-2015-Pleiotropic effects of temperature-r,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7284,PHI:5299,UniProt,Q9ZFU7,GenBank,AAC78127,,,LT2,EutR,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon; spleen,HTH-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26565973,PubMed,10.1371/journal.ppat.1005278,PLoS Pathog. 2015 Nov 13;11(11):e1005278,melissakendall@virginia.edu,"EutR directly activates expression of the Salmonella pathogenicity island 2 in the intramacrophage environment, and thus augments intramacrophage survival. Moreover, EutR is critical for robust dissemination during mammalian infection.",C J Anderson 2015,2015,1 gene,Anderson-2015-Ethanolamine Signaling Promotes,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7285,PHI:5300,UniProt,A4VTH4,GenBank,ABP89413,,,05ZYH33,agaR2,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: pig),SPF,,,,regulators of N-acetyl-galactosamine utilization pathway,,,GalN/GalNAc utilization pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26540018,PubMed,10.1002/mbo3.307,Microbiologyopen. 2015 Nov 5,fengyj@zju.edu.cn,,H Zhang 2015,2015,2 genes,Zhang-2015-Two novel regulators of N-acetyl-ga,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7286,PHI:5300,UniProt,A4VTH4,GenBank,ABP89413,,,05ZYH33,agaR2,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,regulators of N-acetyl-galactosamine utilization pathway,,,GalN/GalNAc utilization pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26540018,PubMed,10.1002/mbo3.307,Microbiologyopen. 2015 Nov 5,fengyj@zju.edu.cn,,H Zhang 2015,2015,2 genes,Zhang-2015-Two novel regulators of N-acetyl-ga,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7287,PHI:5301,UniProt,A4VTH5,GenBank,ABP89414,,,05ZYH33,agaR1,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,regulators of N-acetyl-galactosamine utilization pathway,,,GalN/GalNAc utilization pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26540018,PubMed,10.1002/mbo3.307,Microbiologyopen. 2015 Nov 5,fengyj@zju.edu.cn,,H Zhang 2015,2015,2 genes,Zhang-2015-Two novel regulators of N-acetyl-ga,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7288,PHI:5302,UniProt,E3QJS8,GenBank,EFQ31116,,,M1.001,Str1,,,,,,,31870,Colletotrichum graminicola,645133,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem; leaf,striatin,,,,reduced virulence,yes,no,yes,yes,,reduced; aberrant,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26576029,PubMed,10.1111/mpp.12339,Mol Plant Pathol. 2015 Nov 17,bdshaw@tamu.edu,,C Wang 2015,2015,1 gene,Wang-2015-The Colletotrichum graminicola stria,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7289,PHI:5303,UniProt,D2IV72,GenBank,ACY73852,,,,AaGPx3,,5'GPx::HY/g or h/YG::3'GPx,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),,,,leaf,glutathione peroxidase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2; cumyl-H2O2; tert-butyl-hydroxyperoxide (t-BHP); menadione; KO2; rose bengal (RB); hematoporphyrin (HP); diamide; Congo red (CR); calcofluor white (CFW); SDS; vinclozolin; fludioxonil,H2O2: CHEBI:16240; tert-butyl-hydroxyperoxide (t-BHP): CAS:75-91-2; menadione: CHEBI:28869; KO2: CAS:12030-88-5; rose bengal (RB): CHEBI:52261; hematoporphyrin (HP): CHEBI:36162; Congo red (CR): CHEBI:34653; calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; vinclozolin: CHEBI:9986; fludioxonil: CHEBI:81763,,,,,gene disruption; gene complementation,,,RP,26567914,PubMed,10.1111/1462-2920.13125,Environ Microbiol. 2015 Nov 16,krchung@nchu.edu.tw,"AaGPx3 mutants accumulated higher chitin content than the wild-type and were less sensitive to the cell wall-targeting compounds calcofluor white and Congo red, as well as the fungicides fludioxonil and vinclozolin, suggesting a role of the glutathione systems in fungal cell wall construction.",S L Yang 2015,2015,1 gene,Yang-2015-The glutathione peroxidase-mediated,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7290,PHI:5304,UniProt,Q4QM57,GenBank,AAX87890,,,86-028NP,mobA,,,,,,,727,Haemophilus influenzae,,NTHI 2019,acute respiratory tract infection; chronic respiratory tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,MobA protein catalyzes the final step in the synthesis of the molybdenum guanine dinucleotide (MGD) cofactor that is exclusive to enzymes of the DMSO reductase family.,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26594204,PubMed,10.3389/fmicb.2015.01219,Front Microbiol. 2015 Nov 5;6:1219,u.kappler@uq.edu.au,"No defect in in vitro biofilm formation nor in invasion and adherence to human epithelial cells in tissue culture compared to the wild-type was obseverved. In a murine in vivo model, the mobA mutant showed only a mild attenuation compared to the wild-type (not statistically significant).",R Dhouib 2015,2015,1 gene,Dhouib-2015-Maturation of molybdoenzymes and i,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7291,PHI:5305,UniProt,Q88BF1,GenBank,AAO53620,,,DC3000,OxyR,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Glamour,,,leaf,an oxidative stress-regulated transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene mutation; gene complementation,,,RP,26554736,PubMed,10.1094/MPMI-09-15-0204-R,Mol Plant Microbe Interact. 2015 Nov 11,ishiga.yasuhiro.km@u.tsukuba.ac.jp,The PstDC3000 deltaoxyR mutant showed high sensitivity to oxidative stress in comparison to the wild-type and the complemented line. The host plants of Pst DC3000 including tomato and Arabidopsis inoculated with the deltaoxyR mutant clearly showed reduced disease symptoms as well as reduced bacterial populations.,Y Ishiga 2015,2015,1 gene,Ishiga-2015-Pseudomonas syringae pv. tomato Ox,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7292,PHI:5305,UniProt,Q88BF1,GenBank,AAO53620,,,DC3000,OxyR,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,an oxidative stress-regulated transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene mutation; gene complementation,,,RP,26554736,PubMed,10.1094/MPMI-09-15-0204-R,Mol Plant Microbe Interact. 2015 Nov 11,ishiga.yasuhiro.km@u.tsukuba.ac.jp,The PstDC3000 deltaoxyR mutant showed high sensitivity to oxidative stress in comparison to the wild-type and the complemented line. The host plants of Pst DC3000 including tomato and Arabidopsis inoculated with the deltaoxyR mutant clearly showed reduced disease symptoms as well as reduced bacterial populations.,Y Ishiga 2015,2015,1 gene,Ishiga-2015-Pseudomonas syringae pv. tomato Ox,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7293,PHI:5306,UniProt,G4N3J5,GenBank,EHA52670,,,70-15,MoSKP1,,,,MGG_06351,UniProt: G4N7V6,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,component of E3 ubiquitin ligase,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,reduced; aberrant,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26575697,PubMed,10.1111/mpp.12336,Mol Plant Pathol. 2015 Nov 17,bharat.chattoo@bcmsu.ac.in,"Various RNAi and antisense transformants of MoSKP1in B157 showed reduced sporulation, defective spore morphology, less septation, diffuse nuclei. Further they showed elongated germ tube and were unable to form appressoria.",C Prakash 2015,2015,1 gene,"Prakash-2015-Skp1, a component of E3 Ubiquitin",BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7294,PHI:5307,UniProt,Q3XXA5,GenBank,AFK58539,,,DO,CapD,,E. Faecium U0317 deltacapD (S)(Spectinomycin cassette insertion/replacement),,,,,1352,Enterococcus faecium,547468,U0317,nosocomial bacteremia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney,polysaccharide biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26611826,PubMed,10.1016/j.meegid.2015.11.020,Infect Genet Evol. 2015 Nov 30;37:215-224,tuerkan.sakinc@uniklinik-freiburg.de,"A significant higher bacterial colonization was observed in capD mutant during bacteremia in the animal model, while virulence in a mouse UTI (urinary tract infection) model, there were no obvious differences.",L Ali 2015,2015,1 gene,Ali-2015-Identification and functional charact,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7295,PHI:5308,,no data found,GenBank,BC1G_6313,,,,AQP1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7296,PHI:5309,,no data found,GenBank,BC1G_05803,,,,AQP2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7297,PHI:5311,,no data found,GenBank,BC1G_07858,,,,AQP4,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7298,PHI:5312,,no data found,GenBank,BC1G_13748,,,,AQP5,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7299,PHI:5313,,no data found,GenBank,BC1G_12284,,,,AQP6,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7300,PHI:5314,,no data found,GenBank,BC1G_14337,,,,AQP7,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7301,PHI:5315,,no data found,GenBank,BC1G_14567,,,,AQP8,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,aquaporin,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7302,PHI:5316,,no data found,GenBank,BC1G_12166,,,,AQP9,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,aquaporin,,,,reduced virulence,,,,,,wild type,,reduced,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7303,PHI:5317,,no data found,GenBank,BC1G_05297,,,,PSD,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,phosphatidylserine decarboxylase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7304,PHI:5318,,no data found,GenBank,BC1G_02594,,,,AIF,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,apoptosis-inducing factor 1,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7305,PHI:5319,,no data found,GenBank,BC1G_12671,,,,NQO1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Castlemart,,,fruit; leaf,quinone oxidoreductase,,,,reduced virulence,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7306,PHI:5308,,no data found,GenBank,BC1G_6313,,,,AQP1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7307,PHI:5309,,no data found,GenBank,BC1G_05803,,,,AQP2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7308,PHI:5311,,no data found,GenBank,BC1G_07858,,,,AQP4,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7309,PHI:5312,,no data found,GenBank,BC1G_13748,,,,AQP5,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7310,PHI:5313,,no data found,GenBank,BC1G_12284,,,,AQP6,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7311,PHI:5314,,no data found,GenBank,BC1G_14337,,,,AQP7,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,aquaporin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7312,PHI:5315,,no data found,GenBank,BC1G_14567,,,,AQP8,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,aquaporin,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7313,PHI:5316,,no data found,GenBank,BC1G_12166,,,,AQP9,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,aquaporin,,,,reduced virulence,,,,,,wild type,,reduced,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7314,PHI:5317,,no data found,GenBank,BC1G_05297,,,,PSD,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,phosphatidylserine decarboxylase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7315,PHI:5318,,no data found,GenBank,BC1G_02594,,,,AIF,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,apoptosis-inducing factor 1,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7316,PHI:5319,,no data found,GenBank,BC1G_12671,,,,NQO1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,quinone oxidoreductase,,,,reduced virulence,,,,,,wild type,,wild type,,,,,,,,,gene mutation,,,RP,26527167,PubMed,10.1111/nph.13721,New Phytol. 2015 Nov 3,tsp@ibcas.ac.cn,,B An 2015,2015,12 genes,An-2015-Aquaporin8 regulates cellular developm,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7317,PHI:5320,UniProt,A0A0H2WA86,GenBank,AAU46016,,,ATCC 23344,bprA,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7318,PHI:5321,UniProt,Q63K35,GenBank,ABO26349,,,PHLS 79,bipC,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7319,PHI:5322,UniProt,Q63K34,GenBank,ABO26346,,,PHLS 40,bipB,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7320,PHI:5323,UniProt,A0A069B9Y9,GenBank,AIO83210,,,9,bicA,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7321,PHI:5324,UniProt,Q63K32,GenBank,CAH39007,,,K96243,bsaZ,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7322,PHI:5325,UniProt,A0A0H3HVR2,GenBank,AFI69869,,,1026b,spaP,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7323,PHI:5326,UniProt,A0A0H2WAR1,GenBank,AAU45995,,,ATCC 23344,bsaV,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7324,PHI:5327,UniProt,A0A0H2WAC2,GenBank,AAU45865,,,ATCC 23344,bsaO,small chromosome,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7325,PHI:5328,UniProt,A0A0H3HVS0,GenBank,AFI69879,,,1026b,BP1026B_II1643,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7326,PHI:5329,UniProt,A0A0H3HVF5,GenBank,AFI69880,,,1026b,BP1026B_II1644,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7327,PHI:5330,,no data found,,,,,,P1026B_II1645,,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7328,PHI:5331,UniProt,A0A0H3HU52,GenBank,AFI69882,,,1026b,BP1026B_II1646,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T3SS3 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7329,PHI:5332,UniProt,A0A0H3I0G5,GenBank,AFI69825,,,1026b,BP1026B_II1587,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T6SS5 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7330,PHI:5333,UniProt,A0A0H3HVA0,GenBank,AFI69829,,,1026b,hcp-5,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T6SS5 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7331,PHI:5334,UniProt,A0A069BGU6,GenBank,ALB09969,,,350105,tssF-5,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T6SS5 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7332,PHI:5335,UniProt,A0A0H3HVK0,GenBank,AFI69833,,,1026b,clpV-5,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T6SS5 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7333,PHI:5336,UniProt,A0A0H3HU19,GenBank,AFI69836,,,1026b,tagB-5,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T6SS5 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7334,PHI:5337,UniProt,A0A0H3HY94,GenBank,AFI69837,,,1026b,tagC-5,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T6SS5 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7335,PHI:5338,UniProt,A0A0H3I0I1,GenBank,AFI69840,,,1026b,tssK-5,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T6SS5 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7336,PHI:5339,UniProt,A0A0H3HU22,GenBank,AFI69841,,,1026b,tssL-5,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,T6SS5 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7337,PHI:5340,UniProt,Q9AI43,GenBank,AF285636_13,,,ATCC23344,wcbF,,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7338,PHI:5341,UniProt,Q93UJ6,GenBank,AAK49802,,,,wcbG,,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7339,PHI:5342,UniProt,Q9AI40,GenBank,AAK26464,,,,wcbI,,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7340,PHI:5343,UniProt,Q93UJ3,GenBank,AAK49807,,,,wcbL,,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7341,PHI:5344,UniProt,Q3JP42,GenBank,ABA47701,,,1710b,wcbM,,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7342,PHI:5345,UniProt,A0A0H2WKF8,GenBank,AAU49850,,,ATCC 23344,wcbQ,chromosome 1,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7343,PHI:5346,UniProt,Q63R85,GenBank,CAH36797,,,K96243,wcbS,chromosome 1,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7344,PHI:5347,UniProt,Q9AI28,GenBank,AF285636_28,,,ATCC23344,wcbT,,,,,,,28450,Burkholderia pseudomallei,,DD503,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen,capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26583079,PubMed,10.3389/fcimb.2015.00078,Front Cell Infect Microbiol. 2015 Nov 4;5:78,jonathan.warawa@louisville.edu,,M G Gutierrez 2015,2015,28 genes,Gutierrez-2015-Comprehensive identification of,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7345,PHI:5348,UniProt,R4UG28,GenBank,AGM30717,,,50594,MmpL4a,,,,,,,36809,Mycobacteroides abscessus,319705,subsp. bolletii strain CIP 108541,bacteremia,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,biosynthesis of the complex cell envelope,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,,,,,,,gene mutation: characterised,,,RP,26585558,PubMed,10.1111/mmi.13283,Mol Microbiol. 2015 Nov 20,laurent.kremer@cpbs.cnrs.fr,,A Bernut 2015,2015,1 gene,Bernut-2015-Insights into the smooth-to-rough,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7346,PHI:5349,UniProt,G8BDA6,GenBank,CCE43253,,,CDC317,atc1,,,,,,PHI:5350,5480,Candida parapsilosis,,AM2001/0013,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,trehalase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,26529381,PubMed,10.1016/j.fgb.2015.10.007,Fungal Genet Biol. 2015 Dec;85:45-57,arguelle@um.es,,R Sánchez-Fresneda 2015,2015,2 genes,Sanchez-Fresned-2015-Homozygous deletion of AT,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7347,PHI:5350,UniProt,G8BCG1,GenBank,CCE41826,,,CDC317,ntc1,,,,,,PHI:5349,5480,Candida parapsilosis,,AM2001/0013,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,trehalase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene disruption,,,RP,26529381,PubMed,10.1016/j.fgb.2015.10.007,Fungal Genet Biol. 2015 Dec;85:45-57,arguelle@um.es,,R Sánchez-Fresneda 2015,2015,2 genes,Sanchez-Fresned-2015-Homozygous deletion of AT,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7348,PHI:5351,UniProt,A0A045IPH0,GenBank,ALB17766,,,SCAID 187.0,hadC,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),,,,lung; spleen,encoding a subunit of the HadBC dehydratase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26538472,PubMed,10.1111/mmi.13266,Mol Microbiol. 2015 Nov 5,annaik.quemard@ipbs.fr,"Mutation or deletion ofhadCaffects the biosynthesis of oxygenated mycolic acids, substantially reducing their production level. Additionally, it causes the loss of atypical extra-long mycolic acids, demonstrating the involvement of HadBC in the late elongation steps of mycolic acid biosynthesis.",N Slama 2015,2015,1 gene,Slama-2015-The changes in mycolic acid structu,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7349,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7350,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Pink Lady,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7351,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Ariane,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7352,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Granny Smith,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7353,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Reinette grise du Canada,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7354,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Braeburn,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7355,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7356,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Marie Ménard,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7357,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Saireline,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7358,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Bedan,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7359,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fréquin Rouge,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7360,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Avrolles,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7361,PHI:5352,UniProt,A0A075TXZ8,GenBank,AIG62143,,,NRRL 35695,PePatL,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Petit Jaune,,,fruit,patulin production,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26582186,PubMed,10.1111/mpp.12338,Mol Plant Pathol. 2015 Nov 19,opuel@toulouse.inra.fr,"The deletion of patL caused a drastic decrease of the expression of all pat genes which led to an abscence of patulin production. Pathogenicity studies performedon thirteen apple varieties indicated that the PedeltapatL strain can still infect apples, but the intensity of symptoms compared to the wild type strain is weaker.",S P Snini 2015,2015,1 gene,Snini-2015-The patulin is a cultivar dependent,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7362,PHI:5353,UniProt,I1RIS2,GenBank,ESU09478,,,PH-1,Famfs1,,,,,,,282267,Fusarium asiaticum,,2021,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 5,,,spike,phenamacril-resistance related gene,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26566698,PubMed,10.1002/ps.4186,Pest Manag Sci. 2015 Nov 14,changjun-chen@njau.edu.cn,"Deletion of Famfs1in phenamacril-sensitive or -highly resistant strains, caused significant decrease in effective concentrations inhibiting radial growth by 50% (EC50value). Additionally, the biological fitness parameters (including mycelial growth under different stresses, conidiation, perithecia formation and virulence) of the deletion mutants attenuated significantly.",W Ren 2015,2015,1 gene,Ren-2015-Identification of a novel phenamacril,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7363,PHI:5354,UniProt,W8TNJ3,GenBank,AKJ48565,,,RKI4,ltaS,,,,,,,1280,Staphylococcus aureus,,NCTC 8325-4,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,LTA synthase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: coinjection,,,RP,26599734,PubMed,10.1038/srep17215,Sci Rep. 2015 Nov 24;5:17215,Sci Rep. 2015 Nov 24;5:17215,"Co-injection of eLtaS significantly decreased the survival rate of the mice (Fig. 1f, P = 0.0089), but injection of eLtaS alone was harmless, also, a monoclonal antibody against eLtaS, MAE4, which neutralizes the activity of eLtaS and blocks staphylococcal evasion of phagocytosis.",Y Liu 2015,2015,1 gene,"Liu-2015-MAE4, an eLtaS monoclonal antibody, b",BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7364,PHI:5355,,no data found,GenBank,ALQ80803,,,FUS2,SIX3,,,,,,,5507,Fusarium oxysporum,396571,f. sp. cepae,basal plate rot (onion),monocots,4679,Allium cepa (related: onion),cv. Napoleon,,,bulb,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26609905,PubMed,10.1111/mpp.12346,Mol Plant Pathol. 2015 Nov 26,andrew.taylor@warwick.ac.uk,,A Taylor 2015,2015,10 genes,Taylor-2015-Identification of pathogenicity-re,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7365,PHI:5356,,no data found,GenBank,ALQ80805,,,A21,SIX5,,,,,,,5507,Fusarium oxysporum,396571,f. sp. cepae,basal plate rot (onion),monocots,4679,Allium cepa (related: onion),cv. Napoleon,,,bulb,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26609905,PubMed,10.1111/mpp.12346,Mol Plant Pathol. 2015 Nov 26,andrew.taylor@warwick.ac.uk,,A Taylor 2015,2015,10 genes,Taylor-2015-Identification of pathogenicity-re,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7366,PHI:5357,,no data found,GenBank,ALQ80807,,,FUS2,SIX7,,,,,,,5507,Fusarium oxysporum,396571,f. sp. cepae,basal plate rot (onion),monocots,4679,Allium cepa (related: onion),cv. Napoleon,,,bulb,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26609905,PubMed,10.1111/mpp.12346,Mol Plant Pathol. 2015 Nov 26,andrew.taylor@warwick.ac.uk,,A Taylor 2015,2015,10 genes,Taylor-2015-Identification of pathogenicity-re,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7367,PHI:5358,,no data found,GenBank,ALQ80816,,,PG,SIX9,,,,,,,5507,Fusarium oxysporum,396571,f. sp. cepae,basal plate rot (onion),monocots,4679,Allium cepa (related: onion),cv. Napoleon,,,bulb,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26609905,PubMed,10.1111/mpp.12346,Mol Plant Pathol. 2015 Nov 26,andrew.taylor@warwick.ac.uk,,A Taylor 2015,2015,10 genes,Taylor-2015-Identification of pathogenicity-re,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7368,PHI:5359,,no data found,GenBank,ALQ80826,,,FUS2,SIX10,,,,,,,5507,Fusarium oxysporum,396571,f. sp. cepae,basal plate rot (onion),monocots,4679,Allium cepa (related: onion),cv. Napoleon,,,bulb,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26609905,PubMed,10.1111/mpp.12346,Mol Plant Pathol. 2015 Nov 26,andrew.taylor@warwick.ac.uk,,A Taylor 2015,2015,10 genes,Taylor-2015-Identification of pathogenicity-re,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7369,PHI:5360,,no data found,GenBank,ALQ80835,,,FUS2,SIX12,,,,,,,5507,Fusarium oxysporum,396571,f. sp. cepae,basal plate rot (onion),monocots,4679,Allium cepa (related: onion),cv. Napoleon,,,bulb,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26609905,PubMed,10.1111/mpp.12346,Mol Plant Pathol. 2015 Nov 26,andrew.taylor@warwick.ac.uk,,A Taylor 2015,2015,10 genes,Taylor-2015-Identification of pathogenicity-re,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7370,PHI:5361,,no data found,GenBank,ALQ80845,,,FUS2,SIX14,,,,,,,5507,Fusarium oxysporum,396571,f. sp. cepae,basal plate rot (onion),monocots,4679,Allium cepa (related: onion),cv. Napoleon,,,bulb,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26609905,PubMed,10.1111/mpp.12346,Mol Plant Pathol. 2015 Nov 26,andrew.taylor@warwick.ac.uk,,A Taylor 2015,2015,10 genes,Taylor-2015-Identification of pathogenicity-re,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7371,PHI:5362,,no data found,GenBank,ALQ80846,,,FUS2,C5,,,,,,,5507,Fusarium oxysporum,396571,f. sp. cepae,basal plate rot (onion),monocots,4679,Allium cepa (related: onion),cv. Napoleon,,,bulb,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26609905,PubMed,10.1111/mpp.12346,Mol Plant Pathol. 2015 Nov 26,andrew.taylor@warwick.ac.uk,,A Taylor 2015,2015,10 genes,Taylor-2015-Identification of pathogenicity-re,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7372,PHI:5363,,no data found,GenBank,ALQ80856,,,FUS2,CRX1,,,,,,,5507,Fusarium oxysporum,396571,f. sp. cepae,basal plate rot (onion),monocots,4679,Allium cepa (related: onion),cv. Napoleon,,,bulb,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26609905,PubMed,10.1111/mpp.12346,Mol Plant Pathol. 2015 Nov 26,andrew.taylor@warwick.ac.uk,,A Taylor 2015,2015,10 genes,Taylor-2015-Identification of pathogenicity-re,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7373,PHI:5364,,no data found,GenBank,ALQ80850,,,FUS2,CRX2,,,,,,,5507,Fusarium oxysporum,396571,f. sp. cepae,basal plate rot (onion),monocots,4679,Allium cepa (related: onion),cv. Napoleon,,,bulb,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26609905,PubMed,10.1111/mpp.12346,Mol Plant Pathol. 2015 Nov 26,andrew.taylor@warwick.ac.uk,,A Taylor 2015,2015,10 genes,Taylor-2015-Identification of pathogenicity-re,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7374,PHI:5365,UniProt,Q4WAR8,GenBank,EAL84668,,,Af293,SomA,,,,PtaB,UniProt: Q4X0N1,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,transcription factor,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,26529322,PubMed,10.1371/journal.ppat.1005205,PLoS Pathog. 2015 Nov 3;11(11):e1005205,gbraus@gwdg.de,,C Lin 2015,2015,1 gene,Lin-2015-Transcription Factor SomA Is Required,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7375,PHI:5365,UniProt,Q4WAR8,GenBank,EAL84668,,,Af293,SomA,,,,PtaB,UniProt: Q4X0N1,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,birds,9031,Gallus gallus (related: chicken),,,,egg,transcription factor,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,26529322,PubMed,10.1371/journal.ppat.1005205,PLoS Pathog. 2015 Nov 3;11(11):e1005205,gbraus@gwdg.de,,C Lin 2015,2015,1 gene,Lin-2015-Transcription Factor SomA Is Required,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7376,PHI:5366,UniProt,G4N6P2,GenBank,EHA50711,,,70-15,MoSyn8,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"Qc-SNARE protein homolog, also plays important roles in growth, conidiation, and pathogenicity.",,,,reduced virulence,,no,yes,yes,,reduced,reduced,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,26522477,PubMed,10.1111/nph.13710,New Phytol. 2015 Nov 2,zhgzhang@njau.edu.cn,,Z Qi 2015,2015,1 gene,Qi-2015-The syntaxin protein (MoSyn8) mediates,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7377,PHI:5366,UniProt,G4N6P2,GenBank,EHA50711,,,70-15,MoSyn8,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,"Qc-SNARE protein homolog, also plays important roles in growth, conidiation, and pathogenicity.",,,,reduced virulence,,no,yes,yes,,reduced,reduced,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,26522477,PubMed,10.1111/nph.13710,New Phytol. 2015 Nov 2,zhgzhang@njau.edu.cn,,Z Qi 2015,2015,1 gene,Qi-2015-The syntaxin protein (MoSyn8) mediates,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7378,PHI:5368,UniProt,Q8Y6T0,GenBank,CAC99681,,,EGD-e,lmo1603,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,liver; spleen,aminopeptidase T,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised; gene complementation,,,RP,26610705,PubMed,10.1038/srep17370,Sci Rep. 2015 Nov 27;5:17370,songhh@zafu.edu.cn,,C Cheng 2015,2015,1 gene,Cheng-2015-Aminopeptidase T of M29 Family Acts,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7379,PHI:5369,UniProt,Q57PB8,GenBank,AAX65443,,,SC-B67,MarA,,,,,,,28901,Salmonella enterica,119912,subsp. enterica serovar Choleraesuis strain ATCC13312,bacteremia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26608721,PubMed,10.1016/j.vetmic.2015.09.006,Vet Microbiol. 2015 Dec 31;181(3-4):323-7,thc@dragon.nchu.edu.tw,,J Lee 2015,2015,2 genes,Lee-2015-MarA and ramA regulate virulence in S,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7380,PHI:5370,UniProt,Q57RZ3,GenBank,AAX64518,,,SC-B67,ramA,,,,,,,28901,Salmonella enterica,119912,subsp. enterica serovar Choleraesuis strain ATCC13312,bacteremia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26608721,PubMed,10.1016/j.vetmic.2015.09.006,Vet Microbiol. 2015 Dec 31;181(3-4):323-7,thc@dragon.nchu.edu.tw,,J Lee 2015,2015,2 genes,Lee-2015-MarA and ramA regulate virulence in S,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7381,PHI:5371,UniProt,B9ZUL0,GenBank,CAQ53119,,,v23.1.3,AvrLm4-7,,,,,,,5022,Leptosphaeria maculans,,Nzt-4,blackleg (rapeseed),eudicots,3708,Brassica napus (related: rape),cv. Columbus,,,cotyledon,effector,,,salicylic acid and ethylene pathways,effector (plant avirulence determinant),,,,,,,,,,no,ascorbic acid,ascorbic acid: CHEBI:29073,,,,,functional test in host: direct injection,,,RP,26575525,PubMed,10.1111/mpp.12332,Mol Plant Pathol. 2015 Nov 17,burketova@ueb.cas.cz,,Miroslava Nováková 2015,2015,1 gene,Novakova-2015-Leptosphaeria maculans effector,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7382,PHI:5372,UniProt,A0A0F7A3A1,GenBank,AKF50543,,,HS191,AmrZ,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,regulates cellulose production,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,26564578,PubMed,10.1111/mmi.13278,Mol Microbiol. 2015 Nov 13,maritrini.gallegos@eez.csic.es,,H A Prada-Ramírez 2015,2015,1 gene,Prada-Ramirez-2015-AmrZ regulates cellulose pr,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7383,PHI:5373,UniProt,Q8Y614,GenBank,CAC99966,,,EGD-e,GpsB,,,,PBP A1,UniProt: A0A0E0UYD0,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell division determinant,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,26575090,PubMed,10.1111/mmi.13279,Mol Microbiol. 2015 Nov 17,halbedels@rki.de,,J Rismondo 2015,2015,1 gene,Rismondo-2015-Structure of the bacterial cell,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7384,PHI:5374,UniProt,K9FGI7,GenBank,EKV08309,,,PHI26,afpB,,,,,,,36651,Penicillium digitatum,1170229,isolate PHI26 strain CECT20796,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruit,antifungal protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,RP,26545756,PubMed,10.1007/s00253-015-7110-3,Appl Microbiol Biotechnol. 2015 Nov 7,jmarcos@iata.csic.es,"Strains that artificially express afpB in a constitutive way showed a phenotype of restricted growth, distortion of hyphal morphology and strong reduction in virulence to citrus fruits.",S Garrigues 2015,2015,1 gene,Garrigues-2015-Occurrence and function of fung,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7385,PHI:5374,UniProt,K9FGI7,GenBank,EKV08309,,,PHI26,afpB,,,,,,,36651,Penicillium digitatum,1170229,isolate PHI26 strain CECT20796,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruit,antifungal protein,,,,reduced virulence,,,,,,aberrant,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26545756,PubMed,10.1007/s00253-015-7110-3,Appl Microbiol Biotechnol. 2015 Nov 7,jmarcos@iata.csic.es,"Strains that artificially express afpB in a constitutive way showed a phenotype of restricted growth, distortion of hyphal morphology and strong reduction in virulence to citrus fruits.",S Garrigues 2015,2015,1 gene,Garrigues-2015-Occurrence and function of fung,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7386,PHI:5383,UniProt,Q4ZX47,GenBank,AAY36275,,,B728a,HopZ3,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26586425,PubMed,10.1016/j.celrep.2015.10.029,Cell Rep. 2015 Nov 24;13(8):1670-82,jgreenbe@uchicago.edu,HopZ3 suppresses plant defense by acetylating multiple members of the RPM1 immune complex and its triggering effectors.,J Lee 2015,2015,3 gene,Lee-2015-Acetylation of an NB-LRR Plant Immune,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7387,PHI:5384,UniProt,Q4ZX49,GenBank,AAY36273,,,B728a,AvrB3,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26586425,PubMed,10.1016/j.celrep.2015.10.029,Cell Rep. 2015 Nov 24;13(8):1670-82,jgreenbe@uchicago.edu,HopZ3 suppresses plant defense by acetylating multiple members of the RPM1 immune complex and its triggering effectors.,J Lee 2015,2015,3 gene,Lee-2015-Acetylation of an NB-LRR Plant Immune,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7388,PHI:5385,UniProt,Q4ZYH0,GenBank,AAY35802,,,B728a,AvrRpm1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26586425,PubMed,10.1016/j.celrep.2015.10.029,Cell Rep. 2015 Nov 24;13(8):1670-82,jgreenbe@uchicago.edu,HopZ3 suppresses plant defense by acetylating multiple members of the RPM1 immune complex and its triggering effectors.,J Lee 2015,2015,3 gene,Lee-2015-Acetylation of an NB-LRR Plant Immune,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7389,PHI:5386,UniProt,Q9A0A2,GenBank,AAK33792,,,M1 GAS,S5nA,,,,,,,1358,Lactococcus lactis,416870,MG1363,non-pathogenic,primates,9606,Homo sapiens (related: human),,,,blood,virulence factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26527680,PubMed,10.1074/jbc.M115.677443,J Biol Chem. 2015 Nov 2. pii: jbc.M115.677443,t.proft @auckland.ac.nz,Recombinant S5nA significantly increased the survival of the non-pathogenic bacterium Lactococcus lactis during a human whole blood killing assay in a dose-dependent manner suggesting a role as a S. Pyogenes virulence factor.,L Zheng 2015,2015,1 gene,Zheng-2015-Streptococcal 5'-nucleotidase A (S5,BATCH_055,2015-12-01,MC,,,,,,,,,,,,,
,,Record 7390,PHI:4251,UniProt,Q6PQH2,GenBank,AY586273; Ensembl: PITG_22681,,,90128,EPI1,,"rEPI1 (expressed in E. coli, affinity purified rEPI1 as a fusion protein with the FLAG tag at the N terminus)",,,,,4787,Phytophthora infestans,887080,90128,late blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,extracellular protein inhibitor,,,,effector (plant avirulence determinant),,,,,,,,,,,,,P69B (subtilisin-like serine protease),UniProt: O04678; GenBank: CAA76725; Ensembl: Solyc08g079870,positive co-IP,,functional test in host: transient expression,co-IP experiment. rEPI1 incubated with isolated intercellular tomato fluids. anti-FLAG resin to bind rEPI1 and ppt protein complex. Western blot bands identified with anti-P69 and anti-FLAG.,,AC,15096512,PubMed,10.1074/jbc.M400941200,J Biol Chem.2004 Jun 18;279(25):26370-7,kamoun.1@osu.edu,EPI1 protein inhibits and interacts with pathogenesis-related protein P69B. Virulence effector in defence-counterdefence mechanism. Intercellular/apoplastic fluid from leaf.,Tian et al.,2004,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7391,PHI:4252,UniProt,Q6PQG3,GenBank,AY586282; Ensembl: PITG_12129,,,88069,EPI10,,"rEPI10 (expressed in E. coli, affinity purified rEPI10 as a fusion protein with the FLAG tag at the N terminus)",,,,,4787,Phytophthora infestans,887080,90128,late blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,extracellular protein inhibitor,,,,effector (plant avirulence determinant),,,,,,,,,,,,,P69B (subtilisin-like serine protease),UniProt: O04678; GenBank: CAA76725; Ensembl: Solyc08g079870,positive co-IP,,functional test in host: transient expression,co-IP experiment. rEPI10 incubated with isolated intercellular tomato fluids. anti-FLAG resin to bind rEPI10 and ppt protein complex. Western blot bands identified with anti-P69 and anti-FLAG.,,AC,15980196,PubMed,10.1104/pp.105.061226,Plant Physiol.2005 Jul;138(3):1785-93,kamoun.1@osu.edu,EPI10 protein inhibits and interacts with pathogenesis-related protein P69B. Virulence effector in defence-counterdefence mechanism. Intercellular/apoplastic fluid from leaf.,Tian et al.,2005,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7392,PHI:4253,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1-Emoy2-Citrine,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive response (~20-24 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,,Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7393,PHI:4253,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Emoy2-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive response (~20-24 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,,Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7394,PHI:4254,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Maks9-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Maks9,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive response (~20-24 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,,Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7395,PHI:4255,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Emco5-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive response (~20-24 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,,Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7396,PHI:4256,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Cala2-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Cala2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,no hypersensitive response (48 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,,Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7397,PHI:4257,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Emwa1-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Emwa1,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,no hypersensitive response (48 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,,Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7398,PHI:4253,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Emoy2-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Niederzenz-0,35S:RPP1-NdA-HA,UniProt: D9IW02; GenBank: HM209027,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,hypersensitive response (~20-24 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,,Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7399,PHI:4254,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Maks9-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Maks9,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Niederzenz-0,35S:RPP1-NdA-HA,UniProt: D9IW02; GenBank: HM209027,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,no hypersensitive response (48 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,"interesting note- single amino acid changes in ATR1-Maks9 (to match corresponding ATR1-Emoy2 protein) results in gain of recognition by RPP1-NdA -not curated here, see paper for more detail",Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7400,PHI:4255,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Emco5-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Niederzenz-0,35S:RPP1-NdA-HA,UniProt: D9IW02; GenBank: HM209027,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,no hypersensitive response (48 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,,Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7401,PHI:4256,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Cala2-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Cala2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Niederzenz-0,35S:RPP1-NdA-HA,UniProt: D9IW02; GenBank: HM209027,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,no hypersensitive response (48 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,,Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7402,PHI:4257,UniProt,Q4VKJ6,GenBank,gi61660946,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Emwa1-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Emwa1,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Niederzenz-0,35S:RPP1-NdA-HA,UniProt: D9IW02; GenBank: HM209027,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,no hypersensitive response (48 h post infiltration),functional test in host: transient expression,Agrobacterium-mediated co-expression by infiltration,,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,,Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7403,PHI:4253,UniProt,Q4VKJ6,GenBank,gi61660946; Ensembl: HpaG801867,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Emoy2-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164; Ensembl: AT3G44480,positive co-IP,hypersensitive response (~20-24 h post infiltration),functional test in host: transient expression,"Agrobacterium-mediated co-expression by infiltration, tissue collected ~20-24 h post infiltration, co-IP with anti-GFP to ppt ATR1delta51Citrine, immunoblot detection of RPP1-WsB with anti-HA. parallel IP with anti-HA and immuno blot detection with anti-GFP.",,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,"The LRR, TIR and NBS domains of RPP1-WsB have been mutated and assayed for HR and Co-IP upon coinfiltration with ATR1. Please see paper for further information.",Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7404,PHI:4254,UniProt,Q4VKJ6,GenBank,gi61660946; Ensembl: HpaG801867,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Maks9-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Maks9,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164; Ensembl: AT3G44480,positive co-IP,hypersensitive response (~20-24 h post infiltration),functional test in host: transient expression,"Agrobacterium-mediated co-expression by infiltration, tissue collected ~20-24 h post infiltration, co-IP with anti-GFP to ppt ATR1delta51Citrine, immunoblot detection of RPP1-WsB with anti-HA. parallel IP with anti-HA and immuno blot detection with anti-GFP.",,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,"The LRR, TIR and NBS domains of RPP1-WsB have been mutated and assayed for HR and Co-IP upon coinfiltration with ATR1. Please see paper for further information.",Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7405,PHI:4255,UniProt,Q4VKJ6,GenBank,gi61660946; Ensembl: HpaG801867,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Emco5-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Emco5,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164; Ensembl: AT3G44480,positive co-IP,hypersensitive response (~20-24 h post infiltration),functional test in host: transient expression,"Agrobacterium-mediated co-expression by infiltration, tissue collected ~20-24 h post infiltration, co-IP with anti-GFP to ppt ATR1delta51Citrine, immunoblot detection of RPP1-WsB with anti-HA. parallel IP with anti-HA and immuno blot detection with anti-GFP.",,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,"The LRR, TIR and NBS domains of RPP1-WsB have been mutated and assayed for HR and Co-IP upon coinfiltration with ATR1. Please see paper for further information.",Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7406,PHI:4256,UniProt,Q4VKJ6,GenBank,gi61660946; Ensembl: HpaG801867,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Cala2-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Cala2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164; Ensembl: AT3G44480,negative co-IP,no hypersensitive response (~20-24 h post infiltration),functional test in host: transient expression,"Agrobacterium-mediated co-expression by infiltration, tissue collected ~20-24 h post infiltration, co-IP with anti-GFP to ppt ATR1delta51Citrine, immunoblot detection of RPP1-WsB with anti-HA. parallel IP with anti-HA and immuno blot detection with anti-GFP.",,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,"The LRR, TIR and NBS domains of RPP1-WsB have been mutated and assayed for HR and Co-IP upon coinfiltration with ATR1. Please see paper for further information.",Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7407,PHI:4257,UniProt,Q4VKJ6,GenBank,gi61660946; Ensembl: HpaG801867,,,Consensus sequence from several strains,ATR1 (ATR1NdWsB),,ATR1delta51-Emwa1-Citrine (lacking signal peptide and RXLR motif),,,,,272952,Hyaloperonospora arabidopsidis,,Emwa1,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: tobacco),ecotype Wassilewskija-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,35S:RPP1-WsB-HA,UniProt: Q9LSV1; GenBank: gi3860164; Ensembl: AT3G44480,negative co-IP,no hypersensitive response (~20-24 h post infiltration),functional test in host: transient expression,"Agrobacterium-mediated co-expression by infiltration, tissue collected ~20-24 h post infiltration, co-IP with anti-GFP to ppt ATR1delta51Citrine, immunoblot detection of RPP1-WsB with anti-HA. parallel IP with anti-HA and immuno blot detection with anti-GFP.",,AC,20601497,PubMed,10.1105/tpc.110.075358,Plant Cell.2010 Jul;22(7):2444-58,stask@berkeley.edu,"The LRR, TIR and NBS domains of RPP1-WsB have been mutated and assayed for HR and Co-IP upon coinfiltration with ATR1. Please see paper for further information.",Krasileva et al.,2010,,,AC First Host Target Curation,2016-01-09,RRes,,,,,,,,,,,,,
,,Record 7408,PHI:5387,UniProt,G2XAE9,GenBank,EGY15888,,,VdLs.17,VdCYC8,,,,,,,27337,Verticillium dahliae,,Vd080,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Jimian 11,,,leaf,glucose repression mediator protein,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,RP,26633180,PubMed,10.1371/journal.pone.0144020,PLoS One. 2015 Dec 3;10(12):e0144020,zhuheqin2012@163.com,,Z Li 2015,2015,1 gene,"Li-2015-VdCYC8, Encoding CYC8 Glucose Repressi",BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7409,PHI:5388,UniProt,Q8PLI3,GenBank,AAM36677,,,306,XacFhaB,,,,,,,346,Xanthomonas citri,611301,subsp. citri strain 99-1330,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,virulence factor/non-fimbrial adhesin protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26724481,PubMed,10.1111/mpp.12364,Mol Plant Pathol. 2016 Jan 2,gottig@ibr-conicet.gov.ar,The pre-infiltration of citrus leaves with the regions of XacFhaB impair Xcc growth inducing citrus canker disease resistance.,B S Garavaglia 2016,2016,1 gene,"Garavaglia-2016-XacFhaB adhesin, an important",BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7410,PHI:5389,UniProt,Q59SK6,GenBank,EAK93445,,,SC5314,ZCF21,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,transcriptional repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26700268,PubMed,10.1111/mmi.13320,Mol Microbiol. 2015 Dec 23,christian.perez@uni-wuerzburg.de,,L Böhm 2015,2015,1 gene,Bohm-2015-A Candida albicans regulator of diss,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7411,PHI:5389,UniProt,Q59SK6,GenBank,EAK93445,,,SC5314,ZCF21,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,transcriptional repressor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26700268,PubMed,10.1111/mmi.13320,Mol Microbiol. 2015 Dec 23,christian.perez@uni-wuerzburg.de,,L Böhm 2015,2015,1 gene,Bohm-2015-A Candida albicans regulator of diss,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7412,PHI:5390,UniProt,S8GJB1,GenBank,EPT28584,,,ME49,LCAT,chromosome 8,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,phosphatidylcholine:sterol acyltransferase/acylceramide synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,26694607,PubMed,10.1074/jbc.M115.671974,J Biol Chem. 2015 Dec 22. pii: jbc.M115.671974,icoppens@jhsph.edu,"LCAT-null parasites have impaired growth in vitro, reduced virulence in animals and exhibit delay in egress from host cells. Parasites overexpressing LCAT show increased virulence and faster egress.",V Pszenny 2015,2015,1 gene,Pszenny-2015-A Lipolytic Lecithin_Cholesterol,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7413,PHI:5390,UniProt,S8GJB1,GenBank,EPT28584,,,ME49,LCAT,chromosome 8,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,phosphatidylcholine:sterol acyltransferase/acylceramide synthase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26694607,PubMed,10.1074/jbc.M115.671974,J Biol Chem. 2015 Dec 22. pii: jbc.M115.671974,icoppens@jhsph.edu,"LCAT-null parasites have impaired growth in vitro, reduced virulence in animals and exhibit delay in egress from host cells. Parasites overexpressing LCAT show increased virulence and faster egress.",V Pszenny 2015,2015,1 gene,Pszenny-2015-A Lipolytic Lecithin_Cholesterol,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7414,PHI:5391,UniProt,W7MUV5,GenBank,EWG48192,,,7600,FvSO,,,,,,,117187,Fusarium verticillioides,,M-3125,ear rot (maize),monocots,4577,Zea mays (related: maize),cv. Silver Queen,,,stem; corn ear,WW domain protein required fro growth,,,,loss of pathogenicity,,,,,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26615739,PubMed,10.1016/j.funbio.2015.08.013,Fungal Biol. 2015 Dec;119(12):1158-69,kuldau@psu.edu,"FvSOdeletion mutants (DFvSO) had abnormal distribution of conidia size, and conidia ofDFvSOgerminated much later and slower than wild type. DFvSOwas deficient in hyphal anastomosis, had slower radial growth and produced less fungal biomass than wild type / Production of fumonisin B1 by DFvSO was significantly reduced compared to wild type. Additionally,DFvSO was nonpathogenic to corn ears, stalks and seedlings, likely due to defective growth and development.",L GUO 2015,2015,1 gene,Guo-2015-FvSO regulates vegetative hyphal fusi,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7415,PHI:5392,UniProt,A0A0M5K865,GenBank,ALD51957,,,P6497,PsCRN108,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,CRN effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26714171,PubMed,10.1371/journal.ppat.1005348,PLoS Pathog. 2015 Dec 29;11(12):e1005348,ddou@njau.edu.cn,"Silencing of the PsCRN108 gene reduced P.sojae virulence to soybean, while expression of the gene inNicotiana benthamianaandArabidopsis thalianaenhanced plant susceptibility to P.capsici.",T Song 2015,2015,1 gene,Song-2015-An Oomycete CRN Effector Reprograms,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7416,PHI:5392,UniProt,A0A0M5K865,GenBank,ALD51957,,,P6497,PsCRN108,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,CRN effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptible,,functional test in host: transient expression,,,RP,26714171,PubMed,10.1371/journal.ppat.1005348,PLoS Pathog. 2015 Dec 29;11(12):e1005348,ddou@njau.edu.cn,"Silencing of the PsCRN108 gene reduced P.sojae virulence to soybean, while expression of the gene inNicotiana benthamianaandArabidopsis thalianaenhanced plant susceptibility to P.capsici.",T Song 2015,2015,1 gene,Song-2015-An Oomycete CRN Effector Reprograms,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7417,PHI:5392,UniProt,A0A0M5K865,GenBank,ALD51957,,,P6497,PsCRN108,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,CRN effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptible,,functional test in host: transient expression,,,RP,26714171,PubMed,10.1371/journal.ppat.1005348,PLoS Pathog. 2015 Dec 29;11(12):e1005348,ddou@njau.edu.cn,"Silencing of the PsCRN108 gene reduced P.sojae virulence to soybean, while expression of the gene inNicotiana benthamianaandArabidopsis thalianaenhanced plant susceptibility to P.capsici.",T Song 2015,2015,1 gene,Song-2015-An Oomycete CRN Effector Reprograms,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7418,PHI:5393,UniProt,W7N216,GenBank,EWG54164,,,7600,GLX,chromosome 4,,,,,,117187,Fusarium verticillioides,,5611,ear rot (maize),monocots,4565,Triticum aestivum (related: bread wheat),cv. Huaimai 13,,,spikelet,CWP2 antigen,,,,reduced virulence,,,,,,,,,,no,,,,,susceptible,,gene disruption; gene complementation,,,RP,26720747,PubMed,10.1111/nph.13806,New Phytol. 2015 Dec 31,yucailiao@mail.hzau.edu.cn,"The GLX-deletion Fg and Fv strains had markedly reduced mycotoxin accumulation, and the expression of key genes in mycotoxin metabolism was downregulated.",X Song 2015,2015,1 gene,Song-2015-An antibody that confers plant disea,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7419,PHI:5393,UniProt,X0J8P9,GenBank,EXL97502,,,54006,GLX,,,,,,,5507,Fusarium oxysporum,,297,ear rot (maize),monocots,4565,Triticum aestivum (related: bread wheat),cv. Huaimai 13,,,spikelet,CWP2 antigen,,,,reduced virulence,,,,,,,,,,no,,,,,susceptible,,gene disruption; gene complementation,,,RP,26720747,PubMed,10.1111/nph.13806,New Phytol. 2015 Dec 31,yucailiao@mail.hzau.edu.cn,"The GLX-deletion Fg and Fv strains had markedly reduced mycotoxin accumulation, and the expression of key genes in mycotoxin metabolism was downregulated.",X Song 2015,2015,1 gene,Song-2015-An antibody that confers plant disea,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7420,PHI:5393,UniProt,A0A0E0SJJ3,EMBL,FGRAMPH1_01T21215,,,PH-1,GLX,chromosome 3,,,,,,5518,Fusarium graminearum,,54606,ear rot (maize),monocots,4565,Triticum aestivum (related: bread wheat),cv. Huaimai 13,,,spikelet,CWP2 antigen,,,,reduced virulence,,,,,,,,,,no,,,,,susceptible,,gene disruption; gene complementation,,,RP,26720747,PubMed,10.1111/nph.13806,New Phytol. 2015 Dec 31,yucailiao@mail.hzau.edu.cn,"The GLX-deletion Fg and Fv strains had markedly reduced mycotoxin accumulation, and the expression of key genes in mycotoxin metabolism was downregulated.",X Song 2015,2015,1 gene,Song-2015-An antibody that confers plant disea,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7421,PHI:5394,UniProt,J4UPL6,GenBank,EJP67162,,,ARSEF 2860,mas5,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,heat shock protein classified to Hsp40 group,,,,loss of pathogenicity,,,,,,reduced,,reduced,reduced,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene mutation; gene complementation,,,RP,26714790,PubMed,10.1111/1462-2920.13197,Environ Microbiol. 2015 Dec 30,mgfeng@zju.edu.cn,"Mas5 is not only indispensable for host infection through the normal route of cuticle penetration but required for full conidiation, germination, hyphal growth, and cellular responses to high osmolarity, oxidation, cell wall perturbation, high temperature and ultraviolet B (UV-B) irradiation.",J Wang 2015,2015,1 gene,"Wang-2015-Mas5, a homologue of bacterial DnaJ",BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7422,PHI:5395,UniProt,G4N008,GenBank,EHA52246,,,70-15,MoSec62,chromosome 3,,,,,,318829,Magnaporthe oryzae,1143189,Y-34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,endoplasmic reticulum (ER) membrane transporter for precursors of secretory proteins.,,,,reduced virulence,,no,no,yes,,wild type,,wild type,,no,,,,,,,gene disruption,,,RP,26679839,PubMed,10.1111/mpp.12357,Mol Plant Pathol. 2015 Dec 17,czhe@hainu.edu.cn,,Z Zhou 2015,2015,1 gene,Zhou-2015-Endoplasmic reticulum membrane-bound,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7423,PHI:5396,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,ripBJ,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3880,Medicago truncatula (related: barrel medic),cv. A17,,,root,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26637540,PubMed,10.1074/mcp.M115.0510,Mol Cell Proteomics. 2015 Dec 3. pii: mcp.M115.051078,fabienne.vailleau@toulouse.inra.fr,No differences could be observed between the ripBJ mutant and the wild-type strain for none of these bioassays.,F Lonjon 2015,2015,4 genes,Lonjon-2015-Comparative Secretome Analysis of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7424,PHI:5397,UniProt,A3RV46,GenBank,EAP72659,,,UW551,hpaB,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3880,Medicago truncatula (related: barrel medic),cv. A17,,,root,hypersensitive response and pathogenicity associated,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26637540,PubMed,10.1074/mcp.M115.0510,Mol Cell Proteomics. 2015 Dec 3. pii: mcp.M115.051078,fabienne.vailleau@toulouse.inra.fr,,F Lonjon 2015,2015,4 genes,Lonjon-2015-Comparative Secretome Analysis of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7425,PHI:5398,UniProt,Q8XRI3,GenBank,CAD17999,,,GMI1000,hpaD,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3880,Medicago truncatula (related: barrel medic),cv. A17,,,root,hypersensitive response and pathogenicity associated,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26637540,PubMed,10.1074/mcp.M115.0510,Mol Cell Proteomics. 2015 Dec 3. pii: mcp.M115.051078,fabienne.vailleau@toulouse.inra.fr,,F Lonjon 2015,2015,4 genes,Lonjon-2015-Comparative Secretome Analysis of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7426,PHI:5399,UniProt,Q8XRI9,GenBank,CAD17993,,,GMI1000,hpaG,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3880,Medicago truncatula (related: barrel medic),cv. A17,,,root,hypersensitive response and pathogenicity associated,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26637540,PubMed,10.1074/mcp.M115.0510,Mol Cell Proteomics. 2015 Dec 3. pii: mcp.M115.051078,fabienne.vailleau@toulouse.inra.fr,,F Lonjon 2015,2015,4 genes,Lonjon-2015-Comparative Secretome Analysis of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7427,PHI:5396,UniProt,Q8XTA1,GenBank,CAD17364,,,GMI1000,ripBJ,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26637540,PubMed,10.1074/mcp.M115.0510,Mol Cell Proteomics. 2015 Dec 3. pii: mcp.M115.051078,fabienne.vailleau@toulouse.inra.fr,No differences could be observed between the ripBJ mutant and the wild-type strain for none of these bioassays.,F Lonjon 2015,2015,4 genes,Lonjon-2015-Comparative Secretome Analysis of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7428,PHI:5397,UniProt,A3RV46,GenBank,EAP72659,,,UW551,hpaB,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root,hypersensitive response and pathogenicity associated,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26637540,PubMed,10.1074/mcp.M115.0510,Mol Cell Proteomics. 2015 Dec 3. pii: mcp.M115.051078,fabienne.vailleau@toulouse.inra.fr,,F Lonjon 2015,2015,4 genes,Lonjon-2015-Comparative Secretome Analysis of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7429,PHI:5398,UniProt,Q8XRI3,GenBank,CAD17999,,,GMI1000,hpaD,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root,hypersensitive response and pathogenicity associated,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26637540,PubMed,10.1074/mcp.M115.0510,Mol Cell Proteomics. 2015 Dec 3. pii: mcp.M115.051078,fabienne.vailleau@toulouse.inra.fr,,F Lonjon 2015,2015,4 genes,Lonjon-2015-Comparative Secretome Analysis of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7430,PHI:5399,UniProt,Q8XRI9,GenBank,CAD17993,,,GMI1000,hpaG,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root,hypersensitive response and pathogenicity associated,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26637540,PubMed,10.1074/mcp.M115.0510,Mol Cell Proteomics. 2015 Dec 3. pii: mcp.M115.051078,fabienne.vailleau@toulouse.inra.fr,,F Lonjon 2015,2015,4 genes,Lonjon-2015-Comparative Secretome Analysis of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7431,PHI:5400,UniProt,A5A9S7,GenBank,AM231618,,,BD,MmpL4a,,,,,,,36809,Mycobacteroides abscessus,319705,subsp. bolletii,respiratory infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,multisubstrate efflux pumps,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26710752,PubMed,10.1111/mmi.13306,Mol Microbiol. 2015 Dec 29,stewart.cole@epfl.ch,Tyr842H is missense mutation in the mmpL4a gene was shown to be responsible for the smooth-to-rough morphotype change of the near untreatable opportunistic pathogen. Mycobacterium bolletii due to its failure to export a glycopeptidolipid (GPL). This mutation was pleiotropic and markedly increased virulence in infection models.,R Székely 2015,2015,1 gene,Szekely-2015-Mechanistic insight into mycobact,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7432,PHI:5401,UniProt,A0A0A0S3X0,GenBank,AIW07468,,,00-100,AvrLm2,,,,,,,5022,Leptosphaeria maculans,,00-100,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),cv. DH Topas,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26679637,PubMed,10.1111/mpp.12356,Mol Plant Pathol. 2015 Dec 17,hossein.borhan@agr.gc.ca,,P Haddadi 2015,2015,3 genes,Haddadi-2015-Genome-wide transcriptome analyse,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7433,PHI:5402,UniProt,A4F4L2,GenBank,CAJ90695,,,v23.1.3,AvrLm6,,,,,,,5022,Leptosphaeria maculans,,00-100,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),cv. DH Topas,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26679637,PubMed,10.1111/mpp.12356,Mol Plant Pathol. 2015 Dec 17,hossein.borhan@agr.gc.ca,,P Haddadi 2015,2015,3 genes,Haddadi-2015-Genome-wide transcriptome analyse,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7434,PHI:5403,UniProt,V5TFR9,GenBank,AHB63016,,,v23.1.3,AvrLmJ1,,,,,,,5022,Leptosphaeria maculans,,00-100,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),cv. DH Topas,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26679637,PubMed,10.1111/mpp.12356,Mol Plant Pathol. 2015 Dec 17,hossein.borhan@agr.gc.ca,,P Haddadi 2015,2015,3 genes,Haddadi-2015-Genome-wide transcriptome analyse,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7435,PHI:5404,UniProt,Q8PDI2,GenBank,AAM39675,,,ATCC 33913,pobA,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain Xc1,black rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,4-HBA degradation pathway components,,,4-HBA degradation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26672484,PubMed,10.1038/srep18456,Sci Rep. 2015 Dec 17;5:18456,yawenhe@sjtu.edu.cn,,J Wang 2015,2015,3 genes,Wang-2015-A functional 4-hydroxybenzoate degra,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7436,PHI:5405,UniProt,Q8PDH0,GenBank,AAM39687,,,ATCC 33913,pcaG,,,,,,PHI:5406,339,Xanthomonas campestris,340,pv. campestris strain Xc1,black rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,4-HBA degradation pathway components,,,4-HBA degradation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26672484,PubMed,10.1038/srep18456,Sci Rep. 2015 Dec 17;5:18456,yawenhe@sjtu.edu.cn,,J Wang 2015,2015,3 genes,Wang-2015-A functional 4-hydroxybenzoate degra,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7437,PHI:5406,UniProt,B0RMN9,GenBank,CAP49724,,,B100,pcaH,,,,,,PHI:5405,339,Xanthomonas campestris,340,pv. campestris strain Xc1,black rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,4-HBA degradation pathway components,,,4-HBA degradation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26672484,PubMed,10.1038/srep18456,Sci Rep. 2015 Dec 17;5:18456,yawenhe@sjtu.edu.cn,,J Wang 2015,2015,3 genes,Wang-2015-A functional 4-hydroxybenzoate degra,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7438,PHI:5407,UniProt,P0ACR9,GenBank,CAA38090,,,K-12,MprA,,,,,,,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,liver; spleen,transcriptional repressor of an operon encoding the EmrAB efflux pump.,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26671885,PubMed,10.1093/infdis/jiv584,J Infect Dis. 2015 Dec 15. pii: jiv584,patrick.seed@dm.duke.edu,,M Arshad 2015,2015,1 gene,Arshad-2015-Threading the needle_ small molecu,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7439,PHI:5412,UniProt,Q5NHH2,GenBank,AJI70189,,,SCHU S4,FTT0482c,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,potential virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26714771,PubMed,10.1186/s12864-015-2351-1,BMC Genomics. 2015 Dec 29;16(1):1106,jaques.reifman.civ@mail.mi,,A Wallqvist 2015,2015,5 genes,Wallqvist-2015-Using host-pathogen protein int,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7440,PHI:5413,UniProt,Q5NGE3,GenBank,AJI69956,,,SCHU S4,FTT0902,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,potential virulence factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26714771,PubMed,10.1186/s12864-015-2351-1,BMC Genomics. 2015 Dec 29;16(1):1106,jaques.reifman.civ@mail.mi,,A Wallqvist 2015,2015,5 genes,Wallqvist-2015-Using host-pathogen protein int,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7441,PHI:5414,UniProt,Q5NES6,GenBank,AJI69829,,,SCHU S4,FTT1538c,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,potential virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26714771,PubMed,10.1186/s12864-015-2351-1,BMC Genomics. 2015 Dec 29;16(1):1106,jaques.reifman.civ@mail.mi,,A Wallqvist 2015,2015,5 genes,Wallqvist-2015-Using host-pathogen protein int,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7442,PHI:5415,UniProt,Q5NEQ5,GenBank,AJI69883,,,SCHU S4,FTT1564,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,potential virulence factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26714771,PubMed,10.1186/s12864-015-2351-1,BMC Genomics. 2015 Dec 29;16(1):1106,jaques.reifman.civ@mail.mi,,A Wallqvist 2015,2015,5 genes,Wallqvist-2015-Using host-pathogen protein int,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7443,PHI:5416,UniProt,Q5NEM9,GenBank,AJI69043,,,SCHU S4,FTT1597,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,potential virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26714771,PubMed,10.1186/s12864-015-2351-1,BMC Genomics. 2015 Dec 29;16(1):1106,jaques.reifman.civ@mail.mi,,A Wallqvist 2015,2015,5 genes,Wallqvist-2015-Using host-pathogen protein int,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7444,PHI:5417,UniProt,Q38DU9,GenBank,EAN77021,,,TREU927,TbBBS1,,,,,,,5691,Trypanosoma brucei,,,African trypanosomiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,part of bardet-Biedl syndrome complex,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26721397,PubMed,10.1073/pnas.1518079113,Proc Natl Acad Sci U S A. 2015 Dec 31. pii: 201518079,kenthill@microbio.ucla.edu,,G Langousis 2015,2015,2 genes,Langousis-2015-Loss of the BBSome perturbs end,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7445,PHI:5418,UniProt,Q381Z0,GenBank,EAN80391,,,TREU927,TbBBS9,,,,,,,5691,Trypanosoma brucei,,,African trypanosomiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,part of bardet-Biedl syndrome complex,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26721397,PubMed,10.1073/pnas.1518079113,Proc Natl Acad Sci U S A. 2015 Dec 31. pii: 201518079,kenthill@microbio.ucla.edu,,G Langousis 2015,2015,2 genes,Langousis-2015-Loss of the BBSome perturbs end,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7446,PHI:5419,UniProt,Q8Y2C8,GenBank,CAD13936,,,GMI1000,rpoN1,,rpoN1::Gmr,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf,alternative sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26659655,PubMed,10.1371/journal.pone.0144852,PLoS One. 2015 Dec 11;10(12):e0144852,ctnomura@esf.edu,"It was found that growth on a small range of metabolites, including dicarboxylates, ethanol, nitrate, ornithine, proline and xanthine, were dependent on only the rpoN1gene.",B R Lundgren 2015,2015,2 genes,Lundgren-2015-Defining the Metabolic Functions,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7447,PHI:5420,UniProt,Q8XPG9,GenBank,CAD18822,,,GMI1000,rpoN2,,rpoN2::Gmr,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf,alternative sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26659655,PubMed,10.1371/journal.pone.0144852,PLoS One. 2015 Dec 11;10(12):e0144852,ctnomura@esf.edu,"It was found that growth on a small range of metabolites, including dicarboxylates, ethanol, nitrate, ornithine, proline and xanthine, were dependent on only the rpoN1gene.",B R Lundgren 2015,2015,2 genes,Lundgren-2015-Defining the Metabolic Functions,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7448,PHI:5419,UniProt,Q8Y2C8,GenBank,CAD13936,,,GMI1000,rpoN1,,rpoN1::Gmr,,,,PHI:5420,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf,alternative sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26659655,PubMed,10.1371/journal.pone.0144852,PLoS One. 2015 Dec 11;10(12):e0144852,ctnomura@esf.edu,"It was found that growth on a small range of metabolites, including dicarboxylates, ethanol, nitrate, ornithine, proline and xanthine, were dependent on only the rpoN1gene.",B R Lundgren 2015,2015,2 genes,Lundgren-2015-Defining the Metabolic Functions,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7449,PHI:5420,UniProt,Q8XPG9,GenBank,CAD18822,,,GMI1000,rpoN2,,rpoN2::Gmr,,,,PHI:5419,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Bonny Best,,,leaf,alternative sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26659655,PubMed,10.1371/journal.pone.0144852,PLoS One. 2015 Dec 11;10(12):e0144852,ctnomura@esf.edu,"It was found that growth on a small range of metabolites, including dicarboxylates, ethanol, nitrate, ornithine, proline and xanthine, were dependent on only the rpoN1gene.",B R Lundgren 2015,2015,2 genes,Lundgren-2015-Defining the Metabolic Functions,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7450,PHI:5419,UniProt,Q8Y2C8,GenBank,CAD13936,,,GMI1000,rpoN1,,rpoN1::Gmr,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,leaf,alternative sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26659655,PubMed,10.1371/journal.pone.0144852,PLoS One. 2015 Dec 11;10(12):e0144852,ctnomura@esf.edu,"It was found that growth on a small range of metabolites, including dicarboxylates, ethanol, nitrate, ornithine, proline and xanthine, were dependent on only the rpoN1gene.",B R Lundgren 2015,2015,2 genes,Lundgren-2015-Defining the Metabolic Functions,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7451,PHI:5420,UniProt,Q8XPG9,GenBank,CAD18822,,,GMI1000,rpoN2,,rpoN2::Gmr,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,leaf,alternative sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26659655,PubMed,10.1371/journal.pone.0144852,PLoS One. 2015 Dec 11;10(12):e0144852,ctnomura@esf.edu,"It was found that growth on a small range of metabolites, including dicarboxylates, ethanol, nitrate, ornithine, proline and xanthine, were dependent on only the rpoN1gene.",B R Lundgren 2015,2015,2 genes,Lundgren-2015-Defining the Metabolic Functions,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7452,PHI:5419,UniProt,Q8Y2C8,GenBank,CAD13936,,,GMI1000,rpoN1,,rpoN1::Gmr,,,,PHI:5420,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,leaf,alternative sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26659655,PubMed,10.1371/journal.pone.0144852,PLoS One. 2015 Dec 11;10(12):e0144852,ctnomura@esf.edu,"It was found that growth on a small range of metabolites, including dicarboxylates, ethanol, nitrate, ornithine, proline and xanthine, were dependent on only the rpoN1gene.",B R Lundgren 2015,2015,2 genes,Lundgren-2015-Defining the Metabolic Functions,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7453,PHI:5420,UniProt,Q8XPG9,GenBank,CAD18822,,,GMI1000,rpoN2,,rpoN2::Gmr,,,,PHI:5419,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hawaii 7996,,,leaf,alternative sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26659655,PubMed,10.1371/journal.pone.0144852,PLoS One. 2015 Dec 11;10(12):e0144852,ctnomura@esf.edu,"It was found that growth on a small range of metabolites, including dicarboxylates, ethanol, nitrate, ornithine, proline and xanthine, were dependent on only the rpoN1gene.",B R Lundgren 2015,2015,2 genes,Lundgren-2015-Defining the Metabolic Functions,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7454,PHI:5421,,no data found,GenBank,AAT04886,,,F2365,Lmof2365_2117,,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,rodents,10090,Mus musculus (related: house mouse),A/J,,,liver,cell wall surface anchor protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26724740,PubMed,10.1016/j.micpath.2015.12.012,Microb Pathog. 2015 Dec 25;92:19-25,lawrence@cvm.msstate.edu,The mutant also showed impaired ability to replicate in intestinal epithelial cell and murine macrophages relative to wild type F2365. Lmof2365_2117 contributed toL. monocytogenes attachment to cat fish fillets.,S Reddy 2015,2015,1 gene,Reddy-2015-The role of Listeria monocytogenes,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7455,PHI:5422,UniProt,P45323,GenBank,AAC23339,,,Rd KW20,modA10,,R2866modA10::kan,,,,,727,Haemophilus influenzae,262728,2866,nosocomial infection,rodents,10114,Rattus (related: rat),Sprague-Dawley CO/BS,,,blood,phase-variable DNA methyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26718097,PubMed,10.1016/j.micpath.2015.12.006,Microb Pathog. 2015 Dec 21;92:60-67,Anold.smith@seattlechildrens.org,"The rate of bacteremia was lower in the infant rat model of infection than a wild-type R2866 strain, but the fatality rate was greater.",T M VanWagoner 2015,2015,1 gene,VanWagoner-2015-The modA10 phasevarion of nont,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7456,PHI:5423,UniProt,Q8YG33,GenBank,AAL52510,,,16M,BMEI1329,chromosome 1,deltaBMEI1329::Km,,,,,29459,Brucella melitensis,224914,16M,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,two-component response regulator,,,ABC transporters pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26691825,PubMed,10.1016/j.micpath.2015.11.007,Microb Pathog. 2015 Dec 12;91:92-98,qianhongliu@126.com,"A two-component response regulator gene in the transcriptional regulation pathway, identified through gene deletion and complementary technologies, played an important role in the resistance to the acid-resistance and virulence of Brucella.",Q Liu 2015,2015,1 gene,Liu-2015-Comparative transcriptome analysis of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7457,PHI:5424,UniProt,O25973,GenBank,AAD08472,,,26695,Hpn,,,,UreA; HypA; HypB,"UreA, UniProt: P14916; HypA, UniProt: P0A0U4; HypB, UniProt: O25560",,210,Helicobacter pylori,544406,B128,gastric infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,gastrointestinal tract,protection against nickel and bismuth toxicity,,,,reduced virulence,,,,,,,,,,no,NiCl2,NiCl2: CHEBI:34887,,,,,gene mutation; gene complementation,,,RP,26641249,PubMed,10.1371/journal.ppat.1005312,PLoS Pathog. 2015 Dec 7;11(12):e1005312,hdereuse@pasteur.fr,,D Vinella 2015,2015,2 genes,Vinella-2015-Evolution of Helicobacter_ Acquis,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7458,PHI:5425,UniProt,P0A0V6,GenBank,AAA85859,,,Leu,Hpn-2,,,,HypA; HypB,"HypA, UniProt: P0A0U4; HypB, UniProt: O25560",,210,Helicobacter pylori,544406,B128,gastric infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,gastrointestinal tract,protection against nickel and bismuth toxicity,,,,reduced virulence,,,,,,,,,,no,NiCl2,NiCl2: CHEBI:34887,,,,,gene mutation; gene complementation,,,RP,26641249,PubMed,10.1371/journal.ppat.1005312,PLoS Pathog. 2015 Dec 7;11(12):e1005312,hdereuse@pasteur.fr,,D Vinella 2015,2015,2 genes,Vinella-2015-Evolution of Helicobacter_ Acquis,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7459,PHI:5424,UniProt,O25973,GenBank,AAD08472,,,26695,Hpn,,,,UreA; HypA; HypB,"UreA, UniProt: P14916; HypA, UniProt: P0A0U4; HypB, UniProt: O25560",PHI:5425,210,Helicobacter pylori,544406,B128,gastric infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,gastrointestinal tract,protection against nickel and bismuth toxicity,,,,loss of pathogenicity,,,,,,,,,,no,NiCl2,NiCl2: CHEBI:34887,,,,,gene mutation; gene complementation,,,RP,26641249,PubMed,10.1371/journal.ppat.1005312,PLoS Pathog. 2015 Dec 7;11(12):e1005312,hdereuse@pasteur.fr,,D Vinella 2015,2015,2 genes,Vinella-2015-Evolution of Helicobacter_ Acquis,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7460,PHI:5425,UniProt,P0A0V6,GenBank,AAA85859,,,Leu,Hpn-2,,,,HypA; HypB,"HypA, UniProt: P0A0U4; HypB, UniProt: O25560",PHI:5424,210,Helicobacter pylori,544406,B128,gastric infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,gastrointestinal tract,protection against nickel and bismuth toxicity,,,,loss of pathogenicity,,,,,,,,,,no,NiCl2,NiCl2: CHEBI:34887,,,,,gene mutation; gene complementation,,,RP,26641249,PubMed,10.1371/journal.ppat.1005312,PLoS Pathog. 2015 Dec 7;11(12):e1005312,hdereuse@pasteur.fr,,D Vinella 2015,2015,2 genes,Vinella-2015-Evolution of Helicobacter_ Acquis,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7461,PHI:5426,UniProt,E9EWV4,GenBank,Maa_04503,,,ARSEF 23,Mero-Fus3,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAPK,,,,reduced virulence,,yes,,,,reduced; aberrant,,wild type,,no,KCl; H2O2; Congo red,KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,26714892,PubMed,10.1111/1462-2920.13198,Environ Microbiol. 2015 Dec 30,wfang1@zju.edu.cn,,X Chen 2015,2015,10 genes,Chen-2015-MAPK cascade-mediated regulation of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7462,PHI:5427,UniProt,E9EYM7,GenBank,Maa_05126,,,ARSEF 23,Mero-Hog1,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAPK,,,,reduced virulence,,yes,,,,reduced; aberrant,,wild type,,no,KCl; H2O2; Congo red,KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,26714892,PubMed,10.1111/1462-2920.13198,Environ Microbiol. 2015 Dec 30,wfang1@zju.edu.cn,,X Chen 2015,2015,10 genes,Chen-2015-MAPK cascade-mediated regulation of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7463,PHI:5428,UniProt,E9ESS9,GenBank,Maa_03181,,,ARSEF 23,Mero-Slt2,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAPK,,,,loss of pathogenicity,,yes,,,,reduced; aberrant,,wild type,,no,KCl; H2O2; Congo red,KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,26714892,PubMed,10.1111/1462-2920.13198,Environ Microbiol. 2015 Dec 30,wfang1@zju.edu.cn,,X Chen 2015,2015,10 genes,Chen-2015-MAPK cascade-mediated regulation of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7464,PHI:5429,UniProt,E9EZF4,GenBank,Maa_05403,,,ARSEF 23,Mero-Ime2,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAPK,,,,unaffected pathogenicity,,no,no,no,no,absent (no),,no,no,no,KCl; H2O2; Congo red,KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,26714892,PubMed,10.1111/1462-2920.13198,Environ Microbiol. 2015 Dec 30,wfang1@zju.edu.cn,,X Chen 2015,2015,10 genes,Chen-2015-MAPK cascade-mediated regulation of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7465,PHI:5430,UniProt,E9EWM2,GenBank,Maa_04421,,,ARSEF 23,Mero-Ste7,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAPKK,,,,reduced virulence,,no,,,,reduced; aberrant,,wild type,,no,KCl; H2O2; Congo red,KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,26714892,PubMed,10.1111/1462-2920.13198,Environ Microbiol. 2015 Dec 30,wfang1@zju.edu.cn,,X Chen 2015,2015,10 genes,Chen-2015-MAPK cascade-mediated regulation of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7466,PHI:5431,UniProt,E9EJ96,GenBank,Maa_00856,,,ARSEF 23,Mero-Pbs2,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAPKK,,,,reduced virulence,,no,,,,reduced; aberrant,,wild type,,no,KCl; H2O2; Congo red,KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,26714892,PubMed,10.1111/1462-2920.13198,Environ Microbiol. 2015 Dec 30,wfang1@zju.edu.cn,,X Chen 2015,2015,10 genes,Chen-2015-MAPK cascade-mediated regulation of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7467,PHI:5432,UniProt,E9F0W4,GenBank,Maa_05913,,,ARSEF 23,Mero-Mkk1/2,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAPKK,,,,reduced virulence,,no,,,,reduced; aberrant,,wild type,,no,KCl; H2O2; Congo red,KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,26714892,PubMed,10.1111/1462-2920.13198,Environ Microbiol. 2015 Dec 30,wfang1@zju.edu.cn,,X Chen 2015,2015,10 genes,Chen-2015-MAPK cascade-mediated regulation of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7468,PHI:5433,UniProt,E9EU30,GenBank,Maa_03529,,,ARSEF 23,Mero-Ste11,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAPKKK,,,,unaffected pathogenicity,,no,,,,reduced; aberrant,,wild type,,no,KCl; H2O2; Congo red,KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,26714892,PubMed,10.1111/1462-2920.13198,Environ Microbiol. 2015 Dec 30,wfang1@zju.edu.cn,,X Chen 2015,2015,10 genes,Chen-2015-MAPK cascade-mediated regulation of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7469,PHI:5434,UniProt,E9EX34,GenBank,Maa_04583,,,ARSEF 23,Mero-Bck1,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAPKKK,,,,reduced virulence,,no,,,,reduced; aberrant,,wild type,,no,KCl; H2O2; Congo red,KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,26714892,PubMed,10.1111/1462-2920.13198,Environ Microbiol. 2015 Dec 30,wfang1@zju.edu.cn,,X Chen 2015,2015,10 genes,Chen-2015-MAPK cascade-mediated regulation of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7470,PHI:5435,UniProt,E9EW91,GenBank,Maa_04290,,,ARSEF 23,Mero-Ssk2,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,MAPKKK,,,,reduced virulence,,no,,,,reduced; aberrant,,wild type,,no,KCl; H2O2; Congo red,KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,RP,26714892,PubMed,10.1111/1462-2920.13198,Environ Microbiol. 2015 Dec 30,wfang1@zju.edu.cn,,X Chen 2015,2015,10 genes,Chen-2015-MAPK cascade-mediated regulation of,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7471,PHI:5436,UniProt,Q9FB04,GenBank,AAY28860,,,5005,RopB,,,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,hindlimb,global regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,26714274,PubMed,10.1111/mmi.13294,Mol Microbiol. 2015 Dec 29,mkumaraswami@houstonmethodist.org,Results presented here suggested that a properly aligned RopB dimer interface is important for GAS pathogenesis and highlighted the dimerization interactions as a plausible therapeutic target for the development of novel antimicrobials.,N Makthal 2015,2015,2 genes,Makthal-2015-Structural and functional analysi,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7472,PHI:5437,UniProt,P0C0J0,GenBank,AAA26978,,,86858,speB,,,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,hindlimb,protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,26714274,PubMed,10.1111/mmi.13294,Mol Microbiol. 2015 Dec 29,mkumaraswami@houstonmethodist.org,Results presented here suggested that a properly aligned RopB dimer interface is important for GAS pathogenesis and highlighted the dimerization interactions as a plausible therapeutic target for the development of novel antimicrobials.,N Makthal 2015,2015,2 genes,Makthal-2015-Structural and functional analysi,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7473,PHI:5438,UniProt,P21454,GenBank,CAA78760,,,ML R66,spvB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain X3306,salmonellosis,bony fishes,7955,Danio rerio (related: zebrafish),AB,,,intestine,plasmid virulence gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26723267,PubMed,10.1016/j.fsi.2015.12.033,Fish Shellfish Immunol. 2015 Dec 23;49:252-259,wushuyan@suda.edu.cn,,Y Li 2015,2015,1 gene,Li-2015-Salmonella plasmid virulence gene spvB,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7474,PHI:5439,UniProt,A0A0B4UFC1,GenBank,AJD07337,,,HL1,HrpF,,,,HrpA; HrpG,"HrpA, GenBank: AJD07342; HrpG, GenBank: AJD07336",,317,Pseudomonas syringae,442429,pv. averrhoi strain HL1,bacterial spot (carambola),eudicots,28974,Averrhoa carambola (no common name found),,,,leaf,T3SS-dependent secreted/translocated protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26638129,PubMed,10.1111/mpp.12349,Mol Plant Pathol. 2015 Dec 6,hchuang@dragon.nchu.edu.tw,,Y Huang 2015,2015,1 gene,Huang-2015-The pathogenicity factor HrpF inter,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7475,PHI:5440,UniProt,G4N1P8,GenBank,EHA51620,,,70-15,ABA4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sariceltik,,,leaf,abscisic acid production,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced; aberrant,aberrant,no,abscisic acid,abscisic acid: CHEBI:2365,,,,,gene deletion: full,,,RP,26648962,PubMed,10.3389/fpls.2015.01082,Front Plant Sci. 2015 Dec 1;6:1082,hbais@udel.edu,"EA105, which inhibits appressoria formation, counteracted the virulence-promoting effects of ABA on M. oryzae.",C A Spence 2015,2015,2 genes,Spence-2015-Crucial Roles of Abscisic Acid Bio,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7476,PHI:5441,UniProt,G4N5N0,GenBank,EHA53020,,,70-15,ABA GPCR,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sariceltik,,,leaf,abscisic acid production,,,,unaffected pathogenicity,,no,,,,increased,,wild type,wild type,no,abscisic acid,abscisic acid: CHEBI:2365,,,,,gene deletion: full,,,RP,26648962,PubMed,10.3389/fpls.2015.01082,Front Plant Sci. 2015 Dec 1;6:1082,hbais@udel.edu,"EA105, which inhibits appressoria formation, counteracted the virulence-promoting effects of ABA on M. oryzae.",C A Spence 2015,2015,2 genes,Spence-2015-Crucial Roles of Abscisic Acid Bio,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7477,PHI:5442,UniProt,Q02NA6,GenBank,ABJ11837,,,UCBPP-PA14,lolA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell envelope protein,,,,reduced virulence,,,,,,,,reduced,,yes,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7478,PHI:5443,UniProt,A0A0H2ZGK2,GenBank,ABJ13728,,,UCBPP-PA14,lptH,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell envelope protein,,,,reduced virulence,,,,,,,,reduced,,yes,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7479,PHI:5444,UniProt,Q51479,GenBank,BAA09065,,,PAO1,PA0517,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7480,PHI:5445,UniProt,Q9I380,GenBank,AE004592_5,,,PAO1,PA1645,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7481,PHI:5446,UniProt,Q9I2C6,GenBank,AAG05369,,,PAO1,PA1981,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7482,PHI:5447,UniProt,Q9HXK9,GenBank,AAG07173,,,PAO1,PA3786,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7483,PHI:5448,UniProt,Q9HVT6,GenBank,AAG07873,,,PAO1,PA4485,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7484,PHI:5449,UniProt,Q9HU58,GenBank,AAG08511,,,PAO1,PA5126,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7485,PHI:5442,UniProt,Q02NA6,GenBank,ABJ11837,,,UCBPP-PA14,lolA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,cell envelope protein,,,,reduced virulence,,,,,,,,reduced,,yes,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7486,PHI:5443,UniProt,A0A0H2ZGK2,GenBank,ABJ13728,,,UCBPP-PA14,lptH,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,cell envelope protein,,,,loss of pathogenicity,,,,,,,,reduced,,yes,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7487,PHI:5444,UniProt,Q51479,GenBank,BAA09065,,,PAO1,PA0517,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7488,PHI:5445,UniProt,Q9I380,GenBank,AE004592_5,,,PAO1,PA1645,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7489,PHI:5446,UniProt,Q9I2C6,GenBank,AAG05369,,,PAO1,PA1981,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7490,PHI:5447,UniProt,Q9HXK9,GenBank,AAG07173,,,PAO1,PA3786,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7491,PHI:5448,UniProt,Q9HVT6,GenBank,AAG07873,,,PAO1,PA4485,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7492,PHI:5449,UniProt,Q9HU58,GenBank,AAG08511,,,PAO1,PA5126,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,cell envelope protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26621210,PubMed,10.1038/srep17593,Sci Rep. 2015 Dec 1;5:17593,francesco.imperi@uniroma1.it,"LptH and LolA, responsible for lipopolysaccharide and lipoproteins transport to the outer membrane respectively, and confirmed that they are important for cell envelope stability. LptH was also found to be essential for P. aeruginosaability to cause infection in different animal models.",R Fernández-Piñar 2015,2015,8 genes,Fernandez-Pinar-2015-In vitro and in vivo scre,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7493,PHI:5450,UniProt,H6ULV1,GenBank,AEZ53112,,,Cg-14,gdh2,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,fruit rot,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Avigail,,,fruit,carbon regulation of environmental pH,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26666972,PubMed,10.1111/mpp.12355,Mol Plant Pathol. 2015 Dec 15,dovprusk@volcani.agri.gov.il,,F Bi 2015,2015,2 genes,Bi-2015-Carbon regulation of environmental pH,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7494,PHI:5450,UniProt,H6ULV1,GenBank,AEZ53112,,,Cg-14,gdh2,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,fruit rot,eudicots,3758,Prunus domestica (related: plum),cv. Santa Rosa,,,fruit,carbon regulation of environmental pH,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26666972,PubMed,10.1111/mpp.12355,Mol Plant Pathol. 2015 Dec 15,dovprusk@volcani.agri.gov.il,,F Bi 2015,2015,2 genes,Bi-2015-Carbon regulation of environmental pH,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7495,PHI:5451,,no data found,Geo,TCONS_00011543,,,,gox2,chromosome 6,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,fruit rot,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Avigail,,,fruit,carbon regulation of environmental pH,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26666972,PubMed,10.1111/mpp.12355,Mol Plant Pathol. 2015 Dec 15,dovprusk@volcani.agri.gov.il,,F Bi 2015,2015,2 genes,Bi-2015-Carbon regulation of environmental pH,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7496,PHI:5451,,no data found,Geo,TCONS_00011543,,,,gox2,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,fruit rot,eudicots,3758,Prunus domestica (related: plum),cv. Santa Rosa,,,fruit,carbon regulation of environmental pH,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26666972,PubMed,10.1111/mpp.12355,Mol Plant Pathol. 2015 Dec 15,dovprusk@volcani.agri.gov.il,,F Bi 2015,2015,2 genes,Bi-2015-Carbon regulation of environmental pH,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7497,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7498,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7499,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7500,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7501,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7502,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7503,PHI:5463,UniProt,Q8PRM3,GenBank,AAM39243,,,306,pthA2,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7504,PHI:5463,UniProt,Q8PRM3,GenBank,AAM39243,,,306,pthA2,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7505,PHI:5463,UniProt,Q8PRM3,GenBank,AAM39243,,,306,pthA2,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7506,PHI:5463,UniProt,Q8PRM3,GenBank,AAM39243,,,306,pthA2,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7507,PHI:5463,UniProt,Q8PRM3,GenBank,AAM39243,,,306,pthA2,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7508,PHI:5463,UniProt,Q8PRM3,GenBank,AAM39243,,,306,pthA2,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7509,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7510,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7511,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7512,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7513,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7514,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7515,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7516,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7517,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7518,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7519,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7520,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7521,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7522,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7523,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7524,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7525,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7526,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7527,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7528,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7529,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7530,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7531,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7532,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7533,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7534,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7535,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7536,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7537,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7538,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7539,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7540,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7541,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7542,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7543,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7544,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7545,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7546,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7547,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7548,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7549,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7550,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7551,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7552,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7553,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7554,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7555,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7556,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7557,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7558,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7559,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7560,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7561,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7562,PHI:5462,UniProt,Q8PRG7,GenBank,AAM39311,,,306,pthA4,,,,,,PHI:5464; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7563,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7564,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7565,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7566,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7567,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7568,PHI:5464,UniProt,Q8PRK7,GenBank,AAM39261,,,306,pthA3,,,,,,PHI:5462; PHI:5465,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7569,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462; PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7570,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462; PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7571,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462; PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7572,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462; PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Sorocaba,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7573,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462; PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Natal,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7574,PHI:5465,UniProt,Q8PRN6,GenBank,AAM39226,,,306,pthA1,,,,,,PHI:5462; PHI:5464,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Tahiti,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26709719,PubMed,10.1111/mpp.12359,Mol Plant Pathol. 2015 Dec 28,celso.benedetti@lnbio.cnpem.br,"Although PthA4 is indispensable for canker formation in six Brazilian citrus varieties, PthAs 1 and 3 contributed to canker development in 'Pera' sweet orange, but not in 'Tahiti' lemon. Deletions in two or more pthAgenes reduced bacterial growth in plantamore pronouncedly than single deletions, suggesting an additive role of PthAs in pathogenicity and bacterial fitness.",V Y Abe 2015,2015,4 genes,Abe-2015-Additive roles of PthAs in bacterial,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7575,PHI:5466,UniProt,Q9L524,GenBank,AF260326_1,,,MN8,SrrAB,,,,,,,1280,Staphylococcus aureus,,LAC,osteomyelitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,femur,"bacterial two component system, SrrAB, which is known to help S. aureussurvive in low oxygen",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26684646,PubMed,10.1371/journal.ppat.1005341,PLoS Pathog. 2015 Dec 18;11(12):e1005341,jim.cassat@vanderbilt.edu,"The fitness of an srrABmutant during osteomyelitis was significantly increased by depletion of neutrophils, suggesting that neutrophils impose hypoxic and/or nitrosative stresses on invading bacteria.",A D Wilde 2015,2015,1 gene,Wilde-2015-Bacterial Hypoxic Responses Reveale,BATCH_056,2016-01-01,MC,,,,,,,,,,,,,
,,Record 7576,PHI:3533,UniProt,A3MZ94,GenBank,ABN73480,,,L20,LonA,,,,,,,715,Actinobacillus pleuropneumoniae,,LD20,lung infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; kidney,Lon proteases,,,,reduced virulence,,,,,,,,reduced,,no,KCl; H2O2,KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26796296,PubMed,10.1016/j.micpath.2016.01.009,Microb Pathog. 2016 Jan 12;93:38-43,chunlai.w@hvri.ac.cn,,F Xie 2016,2016,2 genes,"Xie-2016-The Lon protease homologue LonA, not",BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7577,PHI:5467,UniProt,A3N3I4,GenBank,ABN74970,,,L20,LonC,,,,,,,715,Actinobacillus pleuropneumoniae,,LD20,lung infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; kidney,Lon proteases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,KCl; H2O2,KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26796296,PubMed,10.1016/j.micpath.2016.01.009,Microb Pathog. 2016 Jan 12;93:38-43,chunlai.w@hvri.ac.cn,,F Xie 2016,2016,2 genes,"Xie-2016-The Lon protease homologue LonA, not",BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7578,PHI:5468,UniProt,Q9I2N2,GenBank,AE004612_6,,,PAO1,modA,,"PAO1 STM_modA::miniTn5-Km2 mutant inactivating modA(PA1863), KmR",,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,lung,part of molybdate transporter ModABC,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,26758577,PubMed,10.1186/s13104-016-1840-x,BMC Res Notes. 2016 Jan 12;9(1):23,rclevesq@ibis.ulaval.ca,The STM_modA mutant was defective for anaerobic growth and unable to use nitrates in the growth medium for anaerobic respiration.,S Périnet 2016,2016,1 gene,Perinet-2016-Molybdate transporter ModABC is i,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7579,PHI:5468,UniProt,Q9I2N2,GenBank,AE004612_6,,,PAO1,modA,,"PAO1 STM_modA::miniTn5-Km2 mutant inactivating modA(PA1863), KmR",,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),DH1-10,,,,part of molybdate transporter ModABC,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,26758577,PubMed,10.1186/s13104-016-1840-x,BMC Res Notes. 2016 Jan 12;9(1):23,rclevesq@ibis.ulaval.ca,The STM_modA mutant was defective for anaerobic growth and unable to use nitrates in the growth medium for anaerobic respiration.,S Périnet 2016,2016,1 gene,Perinet-2016-Molybdate transporter ModABC is i,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7580,PHI:5469,UniProt,A0A0F7XLK0,GenBank,AAD18613,,,CWL029,CPn0473,,,,,,,83558,Chlamydia pneumoniae,,,pneumonia,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,adhesion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: preventing binding with lipid rafts by depletion of cholesterol,,,RP,26780295,PubMed,10.1111/cmi.12569,Cell Microbiol. 2016 Jan 18,johannes.hegemann@hhu.de,CPn0473-dependent promotion of infection by C. pneumoniae depends on two different domains within the protein and requires intact lipid rafts.,T Fechtner 2016,2016,1 gene,Fechtner-2016-The novel chlamydial adhesin CPn,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7581,PHI:5470,UniProt,G4MNK1,GenBank,EHA57907,,,70-15,MoNgt1,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. PB1,,,leaf,GlcNAc transporter,,,nacetylglucosamine (GlcNAc) catabolic pathway,reduced virulence,,no,no,yes,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26754109,PubMed,10.1111/1462-2920.13215,Environ Microbiol. 2016 Jan 12,asis_datta@rediffmail.com,These mutants showed severely reduced virulence in susceptible rice cultivar due to their inability to neutralize host-derived reactive oxygen species and their failure to develop invasive hyphal growth within the host tissue.,A Kumar 2016,2016,3 genes,Kumar-2016-Magnaporthe oryzae Aminosugar Metab,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7582,PHI:5471,UniProt,G4NB58,GenBank,EHA48820,,,70-15,MoDac,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. PB1,,,leaf,GlcNAc-6-phosphate deacetylase,,,nacetylglucosamine (GlcNAc) catabolic pathway,reduced virulence,,no,no,yes,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26754109,PubMed,10.1111/1462-2920.13215,Environ Microbiol. 2016 Jan 12,asis_datta@rediffmail.com,These mutants showed severely reduced virulence in susceptible rice cultivar due to their inability to neutralize host-derived reactive oxygen species and their failure to develop invasive hyphal growth within the host tissue.,A Kumar 2016,2016,3 genes,Kumar-2016-Magnaporthe oryzae Aminosugar Metab,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7583,PHI:5472,UniProt,G4NB53,GenBank,EHA48815,,,70-15,MoDeam,,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. PB1,,,leaf,GlcN-6-phosphate deaminase,,,nacetylglucosamine (GlcNAc) catabolic pathway,reduced virulence,,no,no,yes,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26754109,PubMed,10.1111/1462-2920.13215,Environ Microbiol. 2016 Jan 12,asis_datta@rediffmail.com,These mutants showed severely reduced virulence in susceptible rice cultivar due to their inability to neutralize host-derived reactive oxygen species and their failure to develop invasive hyphal growth within the host tissue.,A Kumar 2016,2016,3 genes,Kumar-2016-Magnaporthe oryzae Aminosugar Metab,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7584,PHI:5473,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,9625714,PubMed,10.1104/pp.117.2.609,Plant Physiol. 1998 Jun;117(2):609-18,pierre.dewit@medew.fyto.wau.nl,"For both the nonglycosylated and the glycosylated mutant AVR9 peptides, a positive correlation between their affinity to the membrane-localized binding site and their necrosis-inducing activity in MoneyMaker-Cf9 tomato was found.",M Kooman-Gersmann 1998,1998,1 gene,Kooman-Gersmann-1998-Correlation between bindi,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7585,PHI:5474,UniProt,D5KLB5,GenBank,ADE28521,,,,CaAvr4,,,,,,,132184,Cercospora apii,,,leaf spot (celery),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25845605,PubMed,10.1111/mpp.12265,Mol Plant Pathol. 2016 Jan;17(1):84-95,carl.mesarich@gmail.com,"A single region common to CfAvr4 and DsAvr4 was determined to carry a conserved proline residue necessary for the elicitation of this HR. In support of this result, a Cf-4-dependent HR was triggered by mutant CaAvr4 and CbAvr4 proteins carrying an arginine-to-proline substitution at this position.",C H Mesarich 2016,2014,4 genes,Mesarich-2016-A conserved proline residue in D,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7586,PHI:5475,UniProt,D5KLB3,GenBank,ADE28519,,,,CbAvr4,,,,,,,122368,Cercospora beticola,,,leaf spot (sugar beet),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25845605,PubMed,10.1111/mpp.12265,Mol Plant Pathol. 2016 Jan;17(1):84-95,carl.mesarich@gmail.com,"A single region common to CfAvr4 and DsAvr4 was determined to carry a conserved proline residue necessary for the elicitation of this HR. In support of this result, a Cf-4-dependent HR was triggered by mutant CaAvr4 and CbAvr4 proteins carrying an arginine-to-proline substitution at this position.",C H Mesarich 2016,2014,4 genes,Mesarich-2016-A conserved proline residue in D,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7587,PHI:5476,UniProt,Q00363,GenBank,CAA55403,,,,CfAvr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25845605,PubMed,10.1111/mpp.12265,Mol Plant Pathol. 2016 Jan;17(1):84-95,carl.mesarich@gmail.com,"A single region common to CfAvr4 and DsAvr4 was determined to carry a conserved proline residue necessary for the elicitation of this HR. In support of this result, a Cf-4-dependent HR was triggered by mutant CaAvr4 and CbAvr4 proteins carrying an arginine-to-proline substitution at this position.",C H Mesarich 2016,2014,4 genes,Mesarich-2016-A conserved proline residue in D,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7588,PHI:5477,UniProt,N1PIZ7,GenBank,EME41286,,,NZE10,DsAvr4,,,,,,,64363,Dothistroma septosporum,,,Dothistroma needle blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25845605,PubMed,10.1111/mpp.12265,Mol Plant Pathol. 2016 Jan;17(1):84-95,carl.mesarich@gmail.com,"A single region common to CfAvr4 and DsAvr4 was determined to carry a conserved proline residue necessary for the elicitation of this HR. In support of this result, a Cf-4-dependent HR was triggered by mutant CaAvr4 and CbAvr4 proteins carrying an arginine-to-proline substitution at this position.",C H Mesarich 2016,2014,4 genes,Mesarich-2016-A conserved proline residue in D,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7589,PHI:5478,UniProt,Q8Y8H5,GenBank,AEH91970,,,M7,SrtA,,,,,,,1639,Listeria monocytogenes,,BUG 1600,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,"sortase, transpeptidase",,,,reduced virulence,,,,,,,,,,no,chalcone,chalcone: CHEBI:27618,,,,,other evidence: enzyme activity inhibition,,,RP,26826492,PubMed,10.1016/j.bcp.2016.01.018,Biochem Pharmacol. 2016 Jan 27. pii: S0006-2952(16)00042-3,wjf927@jlu.edu.cn,"Chalcone treatment decreased the mortality of infected mice, the bacterial burden in target organs, and the pathological damage to L. monocytogenes-infected mice.",H Li 2016,2016,1 gene,Li-2016-Inhibition of sortase A by chalcone pr,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7590,PHI:5478,UniProt,Q8Y8H5,GenBank,AEH91970,,,M7,SrtA,,,,,,,1639,Listeria monocytogenes,,BUG 1777,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,"sortase, transpeptidase",,,,reduced virulence,,,,,,,,,,no,chalcone,chalcone: CHEBI:27618,,,,,other evidence: enzyme activity inhibition,,,RP,26826492,PubMed,10.1016/j.bcp.2016.01.018,Biochem Pharmacol. 2016 Jan 27. pii: S0006-2952(16)00042-3,wjf927@jlu.edu.cn,"Chalcone treatment decreased the mortality of infected mice, the bacterial burden in target organs, and the pathological damage to L. monocytogenes-infected mice.",H Li 2016,2016,1 gene,Li-2016-Inhibition of sortase A by chalcone pr,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7591,PHI:5479,UniProt,I1RQN9,GenBank,AAL73403,,,,MAP1 (related: GPMK1),,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,mitogen-activated protein kinase,,,,loss of pathogenicity,yes,,,,,reduced,,aberrant,,no,,,,,,,gene disruption,,,RP,12695848,PubMed,10.1007/s00294-003-0379-2,Curr Genet. 2003 May;43(2):87-95. Epub 2003 Mar 7,Schaefer@botanik.uni-hamburg.de,"Disruption of the gpmk1 gene in F. Graminearum results in mutants that are reduced in conidial production, are sexually sterile and are fully apathogenic.",N J Jenczmionka 2003,2003,1 gene,art%3A10.1007%2Fs00294-003-0379-2,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7592,PHI:5480,UniProt,G4MT58,GenBank,EHA55523,,,70-15,MoPyr5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,orotate phosphoribosyl transferase,,,,reduced virulence,yes,yes,yes,,,,,reduced,,no,uridine 5′-phosphate,uridine 5′-phosphate: CHEBI:27232,,,,,gene disruption,,,RP,26810198,PubMed,10.1007/s00253-016-7323-0,Appl Microbiol Biotechnol. 2016 Jan 26,zhgzhang@njau.edu.cn,Exogenous uridine 5′-phosphate (UMP) restored vegetative growth and rescued the defect in pathogenicity on detached barley and rice leaf sheath.,Z Qi 2016,2016,1 gene,Qi-2016-Orotate phosphoribosyl transferase MoP,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7593,PHI:5481,UniProt,Q2V9X3,GenBank,DQ280313,,,FOP-SP2,FTF1,,,,,,,5507,Fusarium oxysporum,251360,f. sp. phaseoli strain FOP-SP1,Fusarium wilt,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blanca,,,leaf,Fusarium transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26817616,PubMed,10.1111/mpp.12373,Mol Plant Pathol. 2016 Jan 28.,josediaz@usal.es,"The attenuation of FTF expression resulted in a marked reduction of virulence, a reduced expression of several SIX (Secreted In Xylem) genes, the best studied family of effectors in F. oxysporum, and also lower levels of SGE1 (Six Gene Expression 1) mRNA, the presumptive regulator of SIX expression.",J Niño-Sánchez 2016,2016,4 genes,Nino-Sanchez-2016-The FTF gene family regulate,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7594,PHI:5482,UniProt,G8GLN8,GenBank,AET08897,,,FOP-SP4,FTF2,chromosome 9,,,,,,5507,Fusarium oxysporum,251360,f. sp. phaseoli strain FOP-SP1,Fusarium wilt,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blanca,,,leaf,Fusarium transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26817616,PubMed,10.1111/mpp.12373,Mol Plant Pathol. 2016 Jan 28.,josediaz@usal.es,"The attenuation of FTF expression resulted in a marked reduction of virulence, a reduced expression of several SIX (Secreted In Xylem) genes, the best studied family of effectors in F. oxysporum, and also lower levels of SGE1 (Six Gene Expression 1) mRNA, the presumptive regulator of SIX expression.",J Niño-Sánchez 2016,2016,4 genes,Nino-Sanchez-2016-The FTF gene family regulate,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7595,PHI:5483,UniProt,A0A0D2YD74,GenBank,KNB15936,,,4287,FTF1,chromosome 14,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,Fusarium transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26817616,PubMed,10.1111/mpp.12373,Mol Plant Pathol. 2016 Jan 28.,josediaz@usal.es,"The attenuation of FTF expression resulted in a marked reduction of virulence, a reduced expression of several SIX (Secreted In Xylem) genes, the best studied family of effectors in F. oxysporum, and also lower levels of SGE1 (Six Gene Expression 1) mRNA, the presumptive regulator of SIX expression.",J Niño-Sánchez 2016,2016,4 genes,Nino-Sanchez-2016-The FTF gene family regulate,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7596,PHI:5484,UniProt,A0A0D2XZG1,GenBank,KNB08567,,,4287,FTF2,chromosome 9,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,Fusarium transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26817616,PubMed,10.1111/mpp.12373,Mol Plant Pathol. 2016 Jan 28.,josediaz@usal.es,"The attenuation of FTF expression resulted in a marked reduction of virulence, a reduced expression of several SIX (Secreted In Xylem) genes, the best studied family of effectors in F. oxysporum, and also lower levels of SGE1 (Six Gene Expression 1) mRNA, the presumptive regulator of SIX expression.",J Niño-Sánchez 2016,2016,4 genes,Nino-Sanchez-2016-The FTF gene family regulate,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7597,PHI:5485,UniProt,Q8XR46,GenBank,CAD18173,,,GMI1000,RipAY,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26823466,PubMed,10.1074/jbc.M115.678953,J Biol Chem. 2016 Jan 28. pii: jbc.M115.678953,mtabuchi@ag.kagawa-u.ac.jp,"The ChaC-domain containing effector RipAY/RSp1022 from R. solanacearum exhibits gamma-glutamyl cyclotransferase (GGCT) activity to degrade the major intracellular redox buffer, glutathione.",S Fujiwara 2016,2016,1 gene,"Fujiwara-2016-RipAY, a plant pathogen effector",BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7598,PHI:5486,UniProt,Q00365,GenBank,CAA78401,,,race 5,ecp2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,62141,Nicotiana paniculata (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,20565616,PubMed,10.1111/j.1364-3703.2004.00239.x,Mol Plant Pathol. 2004 Sep 1;5(5):397-408,pim.lindhout@wur.nl,Absence of Ecp2-recognition did not lead to growth of C. fulvum on Nicotiana plants.,M J D DE KOCK 2004,2004,1 gene,KOCK_et_al-2004-Molecular_Plant_Pathology,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7599,PHI:5487,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,race 4,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,17153926,PubMed,10.1094/MPMI-19-1420,Mol Plant Microbe Interact. 2006 Dec;19(12):1420-30,pierre.dewit@wur.nl,"The interaction of Avr4 with chitin is specific, because it does not interact with other cell wall polysaccharides. In situ fluorescence studies showed that Avr4 also binds to cell walls of C. fulvum during infection of tomato, where it most likely protects the fungus against tomato chitinases, suggesting that Avr4 is a counter-defensive virulence factor.",H A van den Burg 2006,2006,1 gene,van den Burg-2006-Cladosporium fulvum Avr4 pro,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7600,PHI:5488,,no data found,,,,,,Avr1-C039,,,,,,,318829,Magnaporthe oryzae,,4091-5-8,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,"sexual cross, sequencing of resistance conferring allele",,,RP,2016048,PubMed,no data found,Genetics. 1991 Jan;127(1):87-101,,"Several crosses confirm the segregation of three unlinked avirulence genes, AvrI-C039, Avrl- M20I and Avrl-YAMO, alleles of which determine avirulence on rice cultivars CO39, M201, and Yashiro-mochi, respectively.",B Valent 1991,1991,3 genes,Valent-1991-Magnaporthe grisea genes for patho,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7601,PHI:5489,,no data found,,,,,,Avr1-M20I,,,,,,,318829,Magnaporthe oryzae,,4091-5-8,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. M-201,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,"sexual cross, sequencing of resistance conferring allele",,,RP,2016048,PubMed,no data found,Genetics. 1991 Jan;127(1):87-101,,"Several crosses confirm the segregation of three unlinked avirulence genes, AvrI-C039, Avrl- M20I and Avrl-YAMO, alleles of which determine avirulence on rice cultivars CO39, M201, and Yashiro-mochi, respectively.",B Valent 1991,1991,3 genes,Valent-1991-Magnaporthe grisea genes for patho,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7602,PHI:5490,,no data found,,,,,,Avr1-YAMO,,,,,,,318829,Magnaporthe oryzae,,4091-5-8,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Yashiro-mochi,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,"sexual cross, sequencing of resistance conferring allele",,,RP,2016048,PubMed,no data found,Genetics. 1991 Jan;127(1):87-101,,"Several crosses confirm the segregation of three unlinked avirulence genes, AvrI-C039, Avrl- M20I and Avrl-YAMO, alleles of which determine avirulence on rice cultivars CO39, M201, and Yashiro-mochi, respectively.",B Valent 1991,1991,3 genes,Valent-1991-Magnaporthe grisea genes for patho,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7603,PHI:5493,UniProt,F2MNP1,GenBank,AEA94980,,,OG1RF,MafR,,,,,,,1351,Enterococcus faecalis,226185,V583,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal cavity,global response regulators of the Mga/AtxA family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26793169,PubMed,10.3389/fmicb.2015.01521,Front Microbiol. 2016 Jan 11;6:1521,abravo@cib.csic.es,"mafR deletion mutant strain induces a significant lower degree of inflammation in the peritoneal cavity of mice, suggesting that enterococcal cells deficient in MafR are less virulent.",S Ruiz-Cruz 2015,2015,1 gene,Ruiz-Cruz-2015-Global Regulation of Gene Expre,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7604,PHI:5494,UniProt,B8NKI3,GenBank,EED49068,,,NRRL3357,mtfA,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),cv. NC94022,,,seed,master transcription factor gene,,,,unaffected pathogenicity,,,,,,increased,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26805883,PubMed,10.3390/toxins8010029,Toxins (Basel). 2016 Jan 20;8(1). pii: E29,xzhzhenhong@163.com,"mtfA positively affects the pathogenicity of A. flavus when colonizing peanut seeds. AF production in colonized seeds was decreased in the deletion mtfA strain and particularly in the overexpression strain, where only trace amounts were detected.",Z Zhuang 2016,2016,1 gene,Zhuang-2016-The Master Transcription Factor mt,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7605,PHI:5494,UniProt,B8NKI3,GenBank,EED49068,,,NRRL3357,mtfA,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),cv. NC94022,,,seed,master transcription factor gene,,,,increased virulence (hypervirulence),,,,,,reduced,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26805883,PubMed,10.3390/toxins8010029,Toxins (Basel). 2016 Jan 20;8(1). pii: E29,xzhzhenhong@163.com,"mtfA positively affects the pathogenicity of A. flavus when colonizing peanut seeds. AF production in colonized seeds was decreased in the deletion mtfA strain and particularly in the overexpression strain, where only trace amounts were detected.",Z Zhuang 2016,2016,1 gene,Zhuang-2016-The Master Transcription Factor mt,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7606,PHI:5495,UniProt,B3VBK9,GenBank,ACF19427,,,race 5,Ecp6,,,,,,,5499,Fulvia fulva,,race 5,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,18452583,PubMed,10.1111/j.1365-2958.2008.06270.x,Mol Microbiol. 2008 Jul;69(1):119-36,bart.thomma@wur.nl,RNA interference (RNAi)-mediated gene silencing we demonstrate that Ecp6 is instrumental for C. Fulvum virulence on tomato.,M D Bolton 2008,2008,1 gene,Bolton-2008-The novel Cladosporium fulvum lysi,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7607,PHI:5495,UniProt,B3VBK9,GenBank,ACF19427,,,race 5,Ecp6,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,18452583,PubMed,10.1111/j.1365-2958.2008.06270.x,Mol Microbiol. 2008 Jul;69(1):119-36,bart.thomma@wur.nl,C. Fulvum ecp6 when expressed in F. oxysporum f. sp. Lycopersici led to an increase in its pathogenicity on tomato.,M D Bolton 2008,2008,1 gene,Bolton-2008-The novel Cladosporium fulvum lysi,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7608,PHI:5496,UniProt,Q8NID8,GenBank,AGD98923,,,ELH,Avr2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,21118346,PubMed,10.1111/j.1364-3703.2010.00647.x,Mol Plant Pathol. 2011 Jan;12(1):21-30,pierre.dewit@wur.nl,"Two C-terminal cysteine residues and the six amino acid C-terminal tail of Avr2 are required for both Rcr3 inhibitory activity and the ability to trigger a Cf-2-mediated HR. Individual replacement of the lysine-17, lysine-20 or tyrosine-21 residue by alanine did not affect significantly the biological activity of Avr2.",J W V KLOOSTER 2011,2011,1 gene,Van't Klooster-2011-Affinity of Avr2 for tomat,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7609,PHI:5497,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,race 0,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Sonatine,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,16664113,PubMed,no data found,Plant Physiol. 1985 Mar;77(3):642-7,pierre.dewit@fyto.dpw.wag-ur.nl,,P J G M de Wit 1985,1985,1 gene,De Wit-1985-Isolation and Characterization of,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7610,PHI:5497,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,race 2,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Sonatine,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,16664113,PubMed,no data found,Plant Physiol. 1985 Mar;77(3):642-7,pierre.dewit@fyto.dpw.wag-ur.nl,,P J G M de Wit 1985,1985,1 gene,De Wit-1985-Isolation and Characterization of,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7611,PHI:5497,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,race 4,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Sonatine,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,16664113,PubMed,no data found,Plant Physiol. 1985 Mar;77(3):642-7,pierre.dewit@fyto.dpw.wag-ur.nl,,P J G M de Wit 1985,1985,1 gene,De Wit-1985-Isolation and Characterization of,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7612,PHI:5497,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,race 5,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Sonatine,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,16664113,PubMed,no data found,Plant Physiol. 1985 Mar;77(3):642-7,pierre.dewit@fyto.dpw.wag-ur.nl,,P J G M de Wit 1985,1985,1 gene,De Wit-1985-Isolation and Characterization of,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7613,PHI:5497,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,race 9,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Sonatine,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,16664113,PubMed,no data found,Plant Physiol. 1985 Mar;77(3):642-7,pierre.dewit@fyto.dpw.wag-ur.nl,,P J G M de Wit 1985,1985,1 gene,De Wit-1985-Isolation and Characterization of,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7614,PHI:5498,UniProt,G1JUH0,GenBank,AEL16453,,,Ro1,Gr-VAP1,,bait in Yeast two-hybrid,,,,,31243,Globodera rostochiensis,,Ro1-Mierenbos,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato) (non-host bioassay: yeast),cv. GCR161,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,cDNA from S.lyco prey CDNA library similar to Rcr3 from S.pim,UniProt: Q8S335,postive Y2H,,other evidence: yeast two-hybrid,,,RP; AC,22675118,PubMed,10.1073/pnas.1202867109,Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10119-24,Geert.Smant@wur.nl,,J L Lozano-Torres 2012,2012,2 genes,Lozano-Torres-2012-Dual disease resistance med,BATCH_057/AC update,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7615,PHI:5498,UniProt,G1JUH0,GenBank,AEL16453,,,Ro1,Gr-VAP1,,His-FLAG-Gr-VAP1,,,,,31243,Globodera rostochiensis,,Ro1-Mierenbos,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato) (non-host bioassay: pichia pastoris),cv. GCR161,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,Rcr3(pim)-His-HA,UniProt: Q8S335,positive co-IP,,other evidence: co-IP in vitro,,,RP; AC,22675118,PubMed,10.1073/pnas.1202867109,Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10119-24,Geert.Smant@wur.nl,,J L Lozano-Torres 2012,2012,2 genes,Lozano-Torres-2012-Dual disease resistance med,BATCH_057/AC update,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7616,PHI:5498,UniProt,G1JUH0,GenBank,AEL16453,,,Ro1,Gr-VAP1,,transient expression of Gr-VAP1 with native SP in tomato leaves,,,,,31243,Globodera rostochiensis,,Ro1-Mierenbos,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,Cf-2/Rcr3(pim),Rcr3 (pim) UniProt: Q8S335,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,cell death response,,functional test in host: transient expression,,,RP; AC,22675118,PubMed,10.1073/pnas.1202867109,Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10119-24,Geert.Smant@wur.nl,both Cf-2 and Rcr3(pim) are required for Gr-VAP1 cell death response as demonstrated with various host mutant combinations,J L Lozano-Torres 2012,2012,2 genes,Lozano-Torres-2012-Dual disease resistance med,BATCH_057/AC update,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7617,PHI:5500,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,Tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26821568,PubMed,10.1111/mpp.12377,Mol Plant Pathol. 2016 Jan 29,ajb7@cornell.edu,"A tal2a knockout mutant of BLS256 showed virulence comparable to wild type, but plasmid-based overexpression of tal2aat different levels in the wild type reduced virulence in a directly corresponding way.",A W Hummel 2016,2016,1 gene,Hummel-2016-A transcription activator-like eff,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7618,PHI:5500,UniProt,G7TK09,GenBank,AEQ95751,,,BLS256,Tal2a,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26821568,PubMed,10.1111/mpp.12377,Mol Plant Pathol. 2016 Jan 29,ajb7@cornell.edu,"A tal2a knockout mutant of BLS256 showed virulence comparable to wild type, but plasmid-based overexpression of tal2aat different levels in the wild type reduced virulence in a directly corresponding way.",A W Hummel 2016,2016,1 gene,Hummel-2016-A transcription activator-like eff,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7619,PHI:5501,UniProt,Q4ZYH0,GenBank,AAY35802,,,B728a,AvrRpm1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,rpm1; rps2; coi1,UniProt: Q39214; UniProt: Q42484; UniProt: O04197,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26795143,PubMed,10.1007/s00299-016-1932-z,Plant Cell Rep. 2016 Jan 21,xqgeng@sjtu.edu.cn,,X Geng 2016,2016,2 genes,Geng-2016-The Pseudomonas syringae type III ef,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7620,PHI:5502,UniProt,Q6LAD6,GenBank,CAA79815,,,JL1065,AvrRpt2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,rpm1; rps2; coi1,UniProt: Q39214; UniProt: Q42484; UniProt: O04197,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26795143,PubMed,10.1007/s00299-016-1932-z,Plant Cell Rep. 2016 Jan 21,xqgeng@sjtu.edu.cn,,X Geng 2016,2016,2 genes,Geng-2016-The Pseudomonas syringae type III ef,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7621,PHI:5503,UniProt,C9XTL6,GenBank,CBA31267,,,z3032,rpfF,,,,,,,413502,Cronobacter turicensis,,LMG 23827,neonatal death,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,RpfFBc/RpfR system is involved in sensing and responding to DSF signals,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,26725701,PubMed,10.1038/srep18753,Sci Rep. 2016 Jan 4;6:18753,lehnera@fsafety.uzh.ch,"C. turicensis LMG 23827T possesses a functional RpfF/R system that is involved in the regulation of various phenotypes, including colony morphology, biofilm formation and swarming motility. In vivo experiments using the zebrafish embryo model revealed a role of this regulatory system in virulence of this opportunistic pathogen.",A Suppiger 2016,2016,2 genes,Suppiger-2016-The DSF type quorum sensing sign,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7622,PHI:5504,UniProt,C9XTL5,GenBank,CBA31265,,,z3032,rpfR,,,,,,,413502,Cronobacter turicensis,,LMG 23827,neonatal death,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,RpfFBc/RpfR system is involved in sensing and responding to DSF signals,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,26725701,PubMed,10.1038/srep18753,Sci Rep. 2016 Jan 4;6:18753,lehnera@fsafety.uzh.ch,"C. turicensis LMG 23827T possesses a functional RpfF/R system that is involved in the regulation of various phenotypes, including colony morphology, biofilm formation and swarming motility. In vivo experiments using the zebrafish embryo model revealed a role of this regulatory system in virulence of this opportunistic pathogen.",A Suppiger 2016,2016,2 genes,Suppiger-2016-The DSF type quorum sensing sign,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7623,PHI:5542,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,11297411,PubMed,10.1021/bi0023089,Biochemistry. 2001 Mar 27;40(12):3458-66,Jacques.Vervoort@fad.bc.wau.nl,"The (partially) reduced cysteine-modified AVR9 species showed little or no necrosis-inducing activity, demonstrating the importance of the disulfide bridges for biological activity.",H W van den Hooven 2001,2001,1 gene,bi0023089,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7624,PHI:5505,,no data found,GenBank,ERL68916,,,M2,gspN,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7625,PHI:5506,,no data found,GenBank,ERL68917,,,M2,gspC,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7626,PHI:5507,UniProt,A0A2T7FJE6,GenBank,ERL68918,,,M2,gspD,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7627,PHI:5508,,no data found,GenBank,ERL68276,,,M2,gspL,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7628,PHI:5509,,no data found,GenBank,ERL68277,,,M2,gspM,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7629,PHI:5510,,no data found,GenBank,ERL67213,,,M2,gspE,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7630,PHI:5511,,no data found,GenBank,ERL67681,,,M2,gspG,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7631,PHI:5512,,no data found,GenBank,ERL67418,,,M2,gspF,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7632,PHI:5513,,no data found,GenBank,ERL69505,,,M2,gspK,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7633,PHI:5514,,no data found,GenBank,ERL69506,,,M2,gspJ,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7634,PHI:5515,,no data found,GenBank,ERL69507,,,M2,gspI,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7635,PHI:5516,,no data found,GenBank,ERL69508,,,M2,gspH,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7636,PHI:5517,,no data found,GenBank,ERL67454,,,M2,pilB,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7637,PHI:5518,,no data found,GenBank,ERL67455,,,M2,pilC,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7638,PHI:5519,,no data found,GenBank,ERL67456,,,M2,pilD,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7639,PHI:5520,,no data found,GenBank,ERL68916,,,M2,gspN,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7640,PHI:5521,,no data found,GenBank,ERL68917,,,M2,gspC,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7641,PHI:5522,UniProt,A0A2T7FJE6,GenBank,ERL68918,,,M2,gspD,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7642,PHI:5523,,no data found,GenBank,ERL68276,,,M2,gspL,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7643,PHI:5524,,no data found,GenBank,ERL68277,,,M2,gspM,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7644,PHI:5525,,no data found,GenBank,ERL67213,,,M2,gspE,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7645,PHI:5526,,no data found,GenBank,ERL67681,,,M2,gspG,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7646,PHI:5527,,no data found,GenBank,ERL67418,,,M2,gspF,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7647,PHI:5528,,no data found,GenBank,ERL69505,,,M2,gspK,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7648,PHI:5529,,no data found,GenBank,ERL69506,,,M2,gspJ,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7649,PHI:5530,,no data found,GenBank,ERL69507,,,M2,gspI,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7650,PHI:5531,,no data found,GenBank,ERL69508,,,M2,gspH,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7651,PHI:5532,,no data found,GenBank,ERL67454,,,M2,pilB,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7652,PHI:5533,,no data found,GenBank,ERL67455,,,M2,pilC,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7653,PHI:5534,,no data found,GenBank,ERL67456,,,M2,pilD,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,T2SS effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26764912,PubMed,10.1371/journal.ppat.1005391,PLoS Pathog. 2016 Jan 14;12(1):e1005391,mfeldman@wusm.wustl.edu,"Acinetobacter nosocomialisstrain M2 produces a functional T2SS, which is required for full virulence in both theGalleria mellonellaand murine pulmonary infection models.",C M Harding 2016,2016,15 genes,Harding-2016-Medically Relevant Acinetobacter,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7654,PHI:5543,UniProt,B3VBK9,GenBank,ACF19427,,,race 5,Ecp6,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,20724636,PubMed,10.1126/science.1190859,Science. 2010 Aug 20;329(5994):953-5,bart.thomma@wur.nl,"During infection, Ecp6 sequesters chitin oligosaccharides that are released from the cell walls of invading hyphae to prevent elicitation of host immunity.",R de Jonge 2010,2010,1 gene,de Jonge-2010-Conserved fungal LysM effector E,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7655,PHI:5535,UniProt,A8DB99,GenBank,ABV68877,,,SL940,expI,,,,,,,554,Pectobacterium carotovorum,180957,subsp. brasiliense strain 1692,blackleg,eudicots,4113,Solanum tuberosum (related: potato),cv. Valor,,,tuber; stem,production of plant cell wall degrading enzymes,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,26788858,PubMed,10.1111/mpp.12372,Mol Plant Pathol. 2016 Jan 20,lucy.moleleki@up.ac.za,"Inactivation of expIled to reduced production of plant cell wall degrading enzymes (PCWDE), inability to produce acyl homoserine lactone (AHL) and reduced virulence in potato tubers and stems.",L N Moleleki 2016,2016,1 gene,Moleleki-2016-A quorum sensing-defective mutan,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7656,PHI:5536,UniProt,G2XG03,GenBank,EGY18822,,,VdLs.17,VdHog1,chromosome 5,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,292731,Cotinus obovatus (no common name found),,,,leaf,encoding a homolog of a high-osmolarity glycerol (HOG) response mitogen-activated protein kinase,,,MAPkinase,reduced virulence,,,,,,reduced; aberrant,,,,no,NaCl; sorbitol; H2O2; fludioxonil,"D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; C,  NaCl: CHEBI:26710; fludioxonil: CAS:131341-86-1",,,,,gene deletion: full; gene complementation,,,RP,26812120,PubMed,10.1016/j.fgb.2016.01.011,Fungal Genet Biol. 2016 Jan 23;88:13-23,chengmt@bjfu.edu.cn,"Deletion ofVdHog1(DVdHog1), displayed decreased numbers of melanized microsclerotia in culture, heightened sensitivity to hyperosmotic stress, and increased resistance to the fungicide fludioxonil.",Y Wang 2016,2016,1 gene,Wang-2016-The mitogen-activated protein kinase,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7657,PHI:5544,UniProt,Q00365,GenBank,CAA78401,,,race 5,ecp2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,cf-ecp2,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,10628868,PubMed,no data found,Mol Gen Genet. 1999 Dec;262(4-5):839-45,Pim.Lindhout@users.pv.wau.nl,,J P W Haanstra 1999,1999,1 gene,art%3A10.1007%2Fs004380051148.pdf,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7658,PHI:5537,UniProt,Q9C478,GenBank,AF207841_1,,,4224-7-8,AVR-Pita,chromosome 3,,,,,,318829,Magnaporthe oryzae,,CP987,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Yashiro-mochi,Pi-ta,UniProt: Q84UB1,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,11090206,PubMed,10.1105/tpc.12.11.2019,Plant Cell. 2000 Nov;12(11):2019-32,barbara.s.valent@usa.dupont.com,"When introduced into virulent rice pathogens, the cloned gene specifically confers avirulence toward rice cultivars that contain Pi-ta.",M J Orbach 2000,2000,1 gene,Orbach-2000-A telomeric avirulence gene determ,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7659,PHI:5538,UniProt,A0A023UJQ9,GenBank,AHY02126,,,0WU,Avr5(CfCE1),,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,Cf-5,UniProt: Q9ZTK1,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24678832,PubMed,10.1094/MPMI-02-14-0050-R,Mol Plant Microbe Interact. 2014 Aug;27(8):846-57,carl.mesarich@wur.nl,,C H Mesarich 2014,2014,1 gene,Mesarich-2014-Transcriptome sequencing uncover,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7660,PHI:5539,UniProt,A0A097BQG4,GenBank,AIS67218,,,EP155/2,CpBck1,,,,,,,5116,Cryphonectria parasitica,660469,EP155/2,blight (chestnut),eudicots,21020,Castanea sativa (related: chestnut),,,,bark,MAPKKKinase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26757242,PubMed,10.1094/MPMI-08-15-0185-R,Mol Plant Microbe Interact. 2016 Jan 12,dhkim@jbnu.ac.kr,"The CpBck1-null mutant displayed cell wall integrity related phenotypic changes such as abnormal cell morphology and wall formation, and hypersensitivity to cell wall disrupting agents. In addition, the mutant showed severely retarded growth without any sign of normal development such as hyphal differentiation, conidiation, or pigmentation.",J Kim 2016,2016,1 gene,Kim-2016-A Mutant of the Bck1 Homolog from Cry,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7661,PHI:5540,UniProt,G4MKI0,GenBank,EHA57569,,,70-15,MSP1,,,,,,,318829,Magnaporthe oryzae,,KJ301,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Jinheung,,,leaf,"snodprot1 homolog (MSP1), cerato-platanin family protein",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26780420,PubMed,10.1094/MPMI-12-15-0266-R,Mol Plant Microbe Interact. 2016 Jan 18.,kykang@gnu.ac.kr,Magnaporthe oryzae-Secreted Protein MSP1 Induces Cell Death and Elicits Defense Responses in Rice.,Y Wang 2016,2016,1 gene,Wang-2016-Magnaporthe oryzae-Secreted Protein,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7662,PHI:5545,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,Cf-9,UniProt: Q1WM08; GenBank: AAZ57336,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,10755307,PubMed,10.1094/MPMI.2000.13.4.439,Mol Plant Microbe Interact. 2000 Apr;13(4):439-46.,Pierre.deWit@Medew.FYTO.WAU.NL,,R A L Van der Hoorn 2000,2000,2 genes,Van der Hoorn-2000-Agroinfiltration is a versa,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7663,PHI:5546,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,Cf-4,UniProt: Q7DLS4; GenBank: CAA73187,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,10755307,PubMed,10.1094/MPMI.2000.13.4.439,Mol Plant Microbe Interact. 2000 Apr;13(4):439-46.,Pierre.deWit@Medew.FYTO.WAU.NL,,R A L Van der Hoorn 2000,2000,2 genes,Van der Hoorn-2000-Agroinfiltration is a versa,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7664,PHI:5541,UniProt,Q8NID8,GenBank,AGD98923,,,ELH,Avr2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,Cf-2,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,12139631,PubMed,10.1046/j.1365-2958.2002.03060.x,Mol Microbiol. 2002 Aug;45(3):875-84.,Matthieu.Joosten@fyto.dpw.wag-ur.nl,Cladosporium fulvum overcomes Cf-2-mediated resistance by producing truncated AVR2 elicitor proteins,R Luderer 2002,2002,1 gene,Luderer-2002-Cladosporium fulvum overcomes Cf-,BATCH_057,2016-02-01,MC,,,,,,,,,,,,,
,,Record 7665,PHI:5547,UniProt,A0A0H2X5Q6,GenBank,AAY47792,,,8004,prc,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain 17,black rot (Cruciferae),eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,tail-specific protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26804425,PubMed,10.1016/j.resmic.2016.01.002,Res Microbiol. 2016 Jan 20. pii: S0923-2508(16)00007-3,ymhsiao@ctust.edu.tw,,C Liao 2016,2016,1 gene,Liao-2016-Functional characterization and tran,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7666,PHI:5548,UniProt,Q9XC54,GenBank,AAD45271,,,,aphB,,,,,,PHI:5549,666,Vibrio cholerae,,,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine,AphB and OhrR monitor redox-potential changes and respond with different kinetics,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26748713,PubMed,10.1016/j.celrep.2015.12.038,Cell Rep. 2016 Jan 12;14(2):347-54,junzhu@mail.med.upenn.edu,The double mutants were defective in virulence in both oxic and anoxic conditions,Z Liu 2016,2016,2 genes,Liu-2016-Differential Thiol-Based Switches Jum,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7667,PHI:5549,UniProt,A0A0H6ZQK4,GenBank,AKO77174,,,TSY216,ohrR,,,,,,PHI:5548,666,Vibrio cholerae,,,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine,AphB and OhrR monitor redox-potential changes and respond with different kinetics,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26748713,PubMed,10.1016/j.celrep.2015.12.038,Cell Rep. 2016 Jan 12;14(2):347-54,junzhu@mail.med.upenn.edu,The double mutants were defective in virulence in both oxic and anoxic conditions,Z Liu 2016,2016,2 genes,Liu-2016-Differential Thiol-Based Switches Jum,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7668,PHI:5549,UniProt,A0A0H6ZQK4,GenBank,AKO77174,,,TSY216,ohrR,,,,,,,666,Vibrio cholerae,,,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine,AphB and OhrR monitor redox-potential changes and respond with different kinetics,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26748713,PubMed,10.1016/j.celrep.2015.12.038,Cell Rep. 2016 Jan 12;14(2):347-54,junzhu@mail.med.upenn.edu,"The mutants showed reduced virulence in oxic conditions, but not anoxic conditions",Z Liu 2016,2016,2 genes,Liu-2016-Differential Thiol-Based Switches Jum,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7669,PHI:5550,UniProt,Q33CQ4,GenBank,BAE48369,,,Ka4,Bxpel1,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3cl,pine wilt,seed plants,3350,Pinus thunbergii (related: japanese black pine),,,,leaf (whole plant),pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,26797602,PubMed,10.3390/ijms17010125,Int J Mol Sci. 2016 Jan 19;17(1). pii: E125,jrye@njfu.edu.cn,,X Qiu 2016,2016,1 gene,Qiu-2016-Influence of Bxpel1 Gene Silencing by,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7670,PHI:5552,UniProt,Q87AW0,GenBank,AAO29541,,,Temecula1,LesA,,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,leaf,type II secreted lipase/esterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26753904,PubMed,10.1038/srep18598,Sci Rep. 2016 Jan 12;6:18598,amdandekar@ucdavis.edu,,R Nascimento 2016,2016,1 gene,Nascimento-2016-The Type II Secreted Lipase_Es,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7671,PHI:5553,UniProt,C4B8B8,GenBank,AFJ38177,,,CHL346,AVR-Pik,,,,,,,318829,Magnaporthe oryzae,,Sasa2,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,pik,UniProt: F2VYU4,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22805093,PubMed,10.1111/j.1365-313X.2012.05110.x,Plant J. 2012 Dec;72(6):894-907,terauchi@ibrc.or.jp,,H Kanzaki 2012,2012,1 gene,Kanzaki-2012-Arms race co-evolution of Magnapo,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7672,PHI:5554,UniProt,Q4Q4W3,GenBank,CAJ08840,,,Friedlin,LmABCB3,,,,,,,5664,Leishmania major,347515,MHOM/IL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,mitochondrial ABC transporter,,,,reduced virulence,,,,,,,,,,yes,,,,,,,gene deletion: full,,,RP,26728034,PubMed,10.1186/s13071-015-1284-5,Parasit Vectors. 2016 Jan 5;9(1):7,josepv@ipb.csic.es,LmABCB3 is an essential gene as dominant negative inhibition of LmABCB3 is lethal for the parasite. Heterozygous deletion of LmABCB3 allele severely reduces L. major virulence.,M Martínez-García 2016,2016,1 gene,"Martinez-Garcia-2016-LmABCB3, an atypical mito",BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7673,PHI:5555,UniProt,Q8NID8,GenBank,AGD98923,,,ELH,Avr2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,Cf-2,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7674,PHI:5556,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,Cf-4,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7675,PHI:5557,UniProt,A0A023UJQ9,GenBank,AHY02126,,,0WU,Avr5,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,Cf-5,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7676,PHI:5558,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,Cf-9,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7677,PHI:5555,UniProt,Q8NID8,GenBank,AGD98923,,,ELH,Avr2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Potentate,Cf-2,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7678,PHI:5556,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Potentate,Cf-4,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7679,PHI:5557,UniProt,A0A023UJQ9,GenBank,AHY02126,,,0WU,Avr5,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Potentate,Cf-5,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7680,PHI:5558,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Potentate,Cf-9,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7681,PHI:5555,UniProt,Q8NID8,GenBank,AGD98923,,,ELH,Avr2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Vetomold,Cf-2,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7682,PHI:5556,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Vetomold,Cf-4,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7683,PHI:5557,UniProt,A0A023UJQ9,GenBank,AHY02126,,,0WU,Avr5,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Vetomold,Cf-5,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7684,PHI:5558,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Vetomold,Cf-9,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7685,PHI:5555,UniProt,Q8NID8,GenBank,AGD98923,,,ELH,Avr2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Purdue 135,Cf-2,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7686,PHI:5556,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Purdue 135,Cf-4,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7687,PHI:5557,UniProt,A0A023UJQ9,GenBank,AHY02126,,,0WU,Avr5,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Purdue 135,Cf-5,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7688,PHI:5558,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Purdue 135,Cf-9,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7689,PHI:5555,UniProt,Q8NID8,GenBank,AGD98923,,,ELH,Avr2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Ontario 7818,Cf-2,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7690,PHI:5556,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Ontario 7818,Cf-4,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7691,PHI:5557,UniProt,A0A023UJQ9,GenBank,AHY02126,,,0WU,Avr5,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Ontario 7818,Cf-5,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7692,PHI:5558,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Ontario 7818,Cf-9,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7693,PHI:5555,UniProt,Q8NID8,GenBank,AGD98923,,,ELH,Avr2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Ontario 7716,Cf-2,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7694,PHI:5556,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Ontario 7716,Cf-4,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7695,PHI:5557,UniProt,A0A023UJQ9,GenBank,AHY02126,,,0WU,Avr5,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Ontario 7716,Cf-5,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7696,PHI:5558,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Ontario 7716,Cf-9,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,25902074,PubMed,10.1371/journal.pone.0123271,PLoS One. 2015 Apr 22;10(4):e0123271,pierre.dewit@wur.nl,,Y Iida 2015,2015,4 genes,Iida-2015-Novel Mutations Detected in Avirulen,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7697,PHI:5559,UniProt,Q00365,GenBank,CAA78401,,,race 5,ecp2,,,,,,,5499,Fulvia fulva,,race 5,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,extra cellular protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,RP,7859307,PubMed,10.1007/BF00309555,Curr Genet. 1994 Sep;26(3):245-50,,,R Marmeisse 1994,1994,1 gene,Marmeisse et al 1994,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7698,PHI:5559,UniProt,Q00365,GenBank,CAA78401,,,race 5,ecp2,,,,,,,5499,Fulvia fulva,,race 5,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,extra cellular protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,7859307,PubMed,10.1007/BF00309555,Curr Genet. 1994 Sep;26(3):245-50,,,R Marmeisse 1994,1994,1 gene,Marmeisse et al 1994,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7699,PHI:5560,UniProt,Q7MEW9,GenBank,BAC96577,,,YJ016,gbpA,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,mucin-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26755724,PubMed,10.1074/jbc.M115.685321,J Biol Chem. 2016 Mar 11;291(11):5774-87,choish@snu.ac.kr,The gbpA mutant had attenuated virulence and ability of intestinal colonization in a mouse model.,K K Jang 2016,2016,1 gene,Jang-2016-Regulatory Characteristics of Vibrio,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7700,PHI:5561,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,9090881,PubMed,10.1105/tpc.9.3.367,Plant Cell. 1997 Mar;9(3):367-79,pierre.dewit@medew.fyto.wau.nl,,M H A J Joosten 1997,1997,1 gene,Joosten-1997-The biotrophic fungus Cladosporiu,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7701,PHI:5562,UniProt,Q9HEW7,GenBank,AAG48616,,,,Nrf1,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,global nitrogen response factor,,,,unaffected pathogenicity,,,,,,wild type,,,,no,,,,,,,gene deletion: full,,,RP,11277429,PubMed,10.1094/MPMI.2001.14.3.316,Mol Plant Microbe Interact. 2001 Mar;14(3):316-25,pierre.dewit@medew.fyto.wau.nl,"On susceptible tomato plants, the Nrf1-deficient strains were as virulent as wildtype strains of C. fulvum, although the expression of the Avr9 gene was strongly reduced.",A Pérez-García 2001,2001,1 gene,MPMI%2E2001%2E14%2E3%2E316,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7702,PHI:5563,UniProt,Q9I4X3,GenBank,AAG04385,,,PAO1,pqsA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,even-toed ungulates,9823,Sus scrofa (related: pig),,,,skin,quorum sensing,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: gene expression regulation,,,RP,26821927,PubMed,10.1007/s00253-016-7313-2,Appl Microbiol Biotechnol. 2016 Jan 29,ammasgeeta@gmail.com,"Expression studies of genes involved in signalling systems of P. aeruginosaindicated a specific decrease in transcription of pqsA,but not in the lasI or rhlI levels upon clove bud oil application and this leads to attentuated pathogenicity.",H Jayalekshmi 2016,2016,1 gene,H-2016-Clove bud oil reduces kynurenine and in,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7703,PHI:5564,UniProt,Q9F496,GenBank,CAC13110,,,3937,opgG,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,glucans biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,26790533,PubMed,10.1038/srep19619,Sci Rep. 2016 Jan 21;6:19619,jean-marie.lacroix@univ-lille1.fr,"The loss of O-succinyl residue did not affect the virulence of D. dadantii,suggesting that only the glucose backbone of OPGs is required for virulence.",S Bontemps-Gallo 2016,2016,2 genes,Bontemps-Gallo-2016-The opgC gene is required,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7704,PHI:5565,UniProt,E0SF04,GenBank,ADM98746,,,3937,opgC,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,glucans biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,RP,26790533,PubMed,10.1038/srep19619,Sci Rep. 2016 Jan 21;6:19619,jean-marie.lacroix@univ-lille1.fr,"The loss of O-succinyl residue did not affect the virulence of D. dadantii,suggesting that only the glucose backbone of OPGs is required for virulence.",S Bontemps-Gallo 2016,2016,2 genes,Bontemps-Gallo-2016-The opgC gene is required,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7705,PHI:5566,UniProt,P22287,GenBank,AAA03344,,,,Avr9,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,8208859,PubMed,10.1104/pp.103.1.91,Plant Physiol. 1993 Sep;103(1):91-6,,,C F J M Van den Ackerveked 1993,1993,1 gene,Van den Ackerve-1993-The AVR9 race-specific el,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7706,PHI:5567,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,17849712,PubMed,10.1094/MPMI -20-9-1092,Mol Plant Microbe Interact. 2007 Sep;20(9):1092-101,bart.thomma@wur.nl,,H P van Esse 2007,2007,1 gene,van Esse-2007-The chitin-binding Cladosporium,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7707,PHI:5568,UniProt,Q9C478,GenBank,AF207841_1,,,849014,AVR-Pita,chromosome 3,,,,,,318829,Magnaporthe oryzae,,4360-R-62,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,pi-ta,UniProt: Q84UB1,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,10921881,PubMed,10.1093/emboj/19.15.4004,EMBO J. 2000 Aug 1;19(15):4004-14,barbara.s.valent@usa.dupont.com,,Y Jia 2000,2000,1 gene,Jia-2000-Direct interaction of resistance gene,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7708,PHI:5569,UniProt,P21454,GenBank,CAA78760,,,TML R66,spvB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,plasmid virulence genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26811498,PubMed,10.18632/oncotarget.6989,Oncotarget. 2016 Jan 22,wushuyan@suda.edu.cn,,Y Chu 2016,2016,1 gene,Chu-2016-A novel contribution of spvB to patho,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7709,PHI:5570,,no data found,GenBank,NC_016138,,,,pUM505,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,"pUM505 PAI contains genes involved in plasmid replication and conjugative transfer, as well as genes encoding putative proteins with unknown functions.",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26739475,PubMed,10.1007/s10482-015-0642-9,Antonie Van Leeuwenhoek. 2016 Mar;109(3):389-96,marthaisela_ramirez@hotmail.com,pUM505 significantlyincreases the virulence of P. Aeruginosa reference strain PAO1 in lettuce. pUM505 also increased the PAO1 virulence in a murine model and increased cytotoxicity of this strain toward HeLa cells.,E Rodríguez-Andrade 2016,2016,1 gene,Rodriguez-Andra-2016-Genes from pUM505 plasmid,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7710,PHI:5570,,no data found,GenBank,NC_016138,,,,pUM505,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"pUM505 PAI contains genes involved in plasmid replication and conjugative transfer, as well as genes encoding putative proteins with unknown functions.",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26739475,PubMed,10.1007/s10482-015-0642-9,Antonie Van Leeuwenhoek. 2016 Mar;109(3):389-96,marthaisela_ramirez@hotmail.com,pUM505 significantlyincreases the virulence of P. Aeruginosa reference strain PAO1 in lettuce. pUM505 also increased the PAO1 virulence in a murine model and increased cytotoxicity of this strain toward HeLa cells.,E Rodríguez-Andrade 2016,2016,1 gene,Rodriguez-Andra-2016-Genes from pUM505 plasmid,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7711,PHI:5571,UniProt,Q8ZMX2,GenBank,AAL21545,,,LT2,pat,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; cecum,acetyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26810370,PubMed,10.1093/infdis/jiw028,J Infect Dis. 2016 Jan 24. pii: jiw028,yfyao@sjtu.edu.cn,,Y Sang 2016,2016,2 genes,Sang-2016-Protein acetylation is involved in S,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7712,PHI:5572,UniProt,P0A2F2,GenBank,AAC78722,,,,cob,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; cecum,nicotinamide adenine dinucleotide (NAD + )-dependent deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26810370,PubMed,10.1093/infdis/jiw028,J Infect Dis. 2016 Jan 24. pii: jiw028,yfyao@sjtu.edu.cn,,Y Sang 2016,2016,2 genes,Sang-2016-Protein acetylation is involved in S,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7713,PHI:5573,UniProt,A0A0D6I3U0,GenBank,ALE64165,,,33676,envC,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,determinants for intrinsic CAMP resistance,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26810659,PubMed,10.1128/AAC.02699-15,Antimicrob Agents Chemother. 2016 Jan 25. pii: AAC.02699-15,hlee31@uic.edu,,T Oguri 2016,2016,1 gene,Oguri-2016-Identification of EnvC and its cogn,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7714,PHI:5574,UniProt,I1SA65,GenBank,ESU17055,,,PH-1,FgNOT3,,Fgnot3::GEN,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,diverse regulation,,,,reduced virulence,,,,,,reduced,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26799401,PubMed,10.1371/journal.pone.0147481,PLoS One. 2016 Jan 22;11(1):e0147481,lee2443@snu.ac.kr,"Deletion of FgNOT3 resulted in retarded vegetative growth, retarded spore germination, swollen hyphae, and hyper-branching. The deltaFgnot3 mutants also showed impaired sexual and asexual sporulation, decreased virulence, and reduced expression of genes related to conidiogenesis.",D Bui 2016,2016,1 gene,Bui-2016-The FgNot3 Subunit of the Ccr4-Not Co,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7715,PHI:5575,UniProt,P9WF41,GenBank,CCP46238,,,WhiB3,H37Rv,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,"4S redox sensor protein, regulates ergothioneine (EGT) production",,,,reduced virulence,,,,,,,,,,no,H2O2; paraquat; menadione; cumene hydroperoxide,H2O2: CHEBI:16240; paraquat: CHEBI:34905; menadione: CHEBI:28869; cumene hydroperoxide: CHEBI:78673,,,,,gene mutation; gene complementation,,,RP,26774486,PubMed,10.1016/j.celrep.2015.12.056,Cell Rep. 2016 Jan 26;14(3):572-85,asteyn@uab.edu,,V Saini 2016,2016,1 gene,Saini-2016-Ergothioneine Maintains Redox and B,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7716,PHI:5576,UniProt,B3VBK9,GenBank,ACF19427,,,race 5,Ecp6,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: tomato),Msk8 cell line,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,23840930,PubMed,10.7554/eLife.00790,Elife. 2013 Jul 2;2:e00790,bart.thomma@wur.nl,,A Sánchez-Vallet 2013,2013,1 gene,Sanchez-Vallet-2013-Fungal effector Ecp6 outco,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7717,PHI:5577,UniProt,P9WNA9,GenBank,CCP43014,,,H37Rv,esx-3,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,reduced,,yes,,,,,,,gene mutation,,,RP,26729876,PubMed,10.1073/pnas.1523321113,Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):E348-57,jphilips@dom.wustl.edu,,J M Tufariello 2016,2016,1 gene,Tufariello-2016-Separable roles for Mycobacter,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7718,PHI:5578,UniProt,P9WJY3,GenBank,CCP44169,,,H37Rv,Rv1410c,,,,,,PHI:5579,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,MFS-type drug efflux transporter P55,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26751071,PubMed,10.1371/journal.ppat.1005351,PLoS Pathog. 2016 Jan 11;12(1):e1005351,erubin@hsph.harvard.edu,,A J Martinot 2016,2016,2 genes,Martinot-2016-Mycobacterial Metabolic Syndrome,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7719,PHI:5579,UniProt,P9WK45,GenBank,CCP44170,,,H37Rv,LprG,,,,,,PHI:5578,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),CBySmn.Cg-Prkdc<scid>/J,,,,lipoarabinomannan carrier protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26751071,PubMed,10.1371/journal.ppat.1005351,PLoS Pathog. 2016 Jan 11;12(1):e1005351,erubin@hsph.harvard.edu,,A J Martinot 2016,2016,2 genes,Martinot-2016-Mycobacterial Metabolic Syndrome,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7720,PHI:5581,UniProt,P9WNI7,GenBank,CCP45134,,,H37Rv,EsxO(Rv2346c),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),,,,macrophage,ESAT-6 like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26786654,PubMed,10.1016/j.tube.2015.11.006,Tuberculosis (Edinb). 2016 Jan;96:44-57,asonawane@kiitbiotech.ac.in,"Expression of Mtb Rv2346c (esxO), a member of ESAT-6 family proteins, in non-pathogenic Mycobacterium smegmatisstrain (MsmRv2346c) aids host cell invasion and intracellular bacillary persistence.",S Mohanty 2016,2016,1 gene,Mohanty-2016-Mycobacterium tuberculosis EsxO (,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7721,PHI:5582,,no data found,,,,,,CfHNNI1,,,,,,,5499,Fulvia fulva,,race 4,leaf mold (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,plant necrosis inducer,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence,pSfinx::CfHNNI1,,RP,17273821,PubMed,10.1007/s11103-007-9136-0,Plant Mol Biol. 2007 May;64(1-2):89-101,xzhcai@zju.edu.cn,CfHNNI1 transgenic plants also exhibited induced resistance to Pseudomonas syringae pv.tabaci and Tobacco mosaic virus.,X Cai 2007,2007,1 gene,art%3A10.1007%2Fs11103-007-9136-0,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7722,PHI:5582,,no data found,,,,,,CfHNNI1,,,,,,,4792,Phytophthora nicotianae,1368100,var. nicotianae,black shank (tobacco),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,plant necrosis inducer,,,,reduced virulence,,,,,,,,,,no,,,,,resistance,,other evidence,pSfinx::CfHNNI1,,RP,17273821,PubMed,10.1007/s11103-007-9136-0,Plant Mol Biol. 2007 May;64(1-2):89-101,xzhcai@zju.edu.cn,CfHNNI1 transgenic plants also exhibited induced resistance to Pseudomonas syringae pv.tabaci and Tobacco mosaic virus.,X Cai 2007,2007,1 gene,art%3A10.1007%2Fs11103-007-9136-0,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7723,PHI:5582,,no data found,,,,,,CfHNNI1,,,,,,,317,Pseudomonas syringae,322,pv. tabaci,wildfire disease,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,plant necrosis inducer,,,,reduced virulence,,,,,,,,,,no,,,,,resistance,,other evidence,pSfinx::CfHNNI1,,RP,17273821,PubMed,10.1007/s11103-007-9136-0,Plant Mol Biol. 2007 May;64(1-2):89-101,xzhcai@zju.edu.cn,CfHNNI1 transgenic plants also exhibited induced resistance to Pseudomonas syringae pv.tabaci and Tobacco mosaic virus.,X Cai 2007,2007,1 gene,art%3A10.1007%2Fs11103-007-9136-0,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7724,PHI:5583,UniProt,A7EKI7,GenBank,EDO03353,,,1980 UF-70,FoxE2,,,,,,,5180,Sclerotinia sclerotiorum,,JRUF1,white mold; sclerotinia stem rot; stalk rot; sclerotinia head rot,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,regulation of sexual reproduction,,,,unaffected pathogenicity,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26756829,PubMed,10.1094/PHYTO-08-15-0181-R,Phytopathology. 2016 Mar 22:PHYTO08150181R,panhongyu@jlu.edu.cn,"Ss-FoxE2 appears to be necessary for the regulation of sexual reproduction, but may not affect the pathogenicity and vegetative development of S. Sclerotiorum significantly.",L Wang 2016,2016,1 gene,Wang-2016-The Sclerotinia sclerotiorum FoxE2 g,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7725,PHI:5584,UniProt,Q00363,GenBank,CAA55403,,,,Avr4,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,Cf-4,UniProt: Q7DLS4; GenBank: CAA73187,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence,tobacco rattle virus (TRV)-mediated VIGS,,RP,26765243,PubMed,10.1111/nph.13802,New Phytol. 2016 Apr;210(2):627-42,Robatzek@TSL.ac.uk,Cf-4 interacts with SlSOBIR1 at the plasma membrane,J Postma 2016,2016,1 gene,Postma-2016-Avr4 promotes Cf-4 receptor-like p,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7726,PHI:5585,UniProt,Q9I4X3,GenBank,AE004532_9,,,PAO1,pqsA,,,,,,PHI:5586,287,Pseudomonas aeruginosa,208964,PAO1,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,quinolone production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26788419,PubMed,10.7717/peerj.1495,PeerJ. 2016 Jan 7;4:e1495,zhangym@musc.edu,"The reduction in virulence of the pqsAB mutant was attributed to the complete loss of quinolone production, while production of DHQ in the pqsB and pqsC mutant maintained pathogenicity towards the nematodes.",J D Gruber 2016,2016,3 genes,"Gruber-2016-The role of 2,4-dihydroxyquinoline",BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7727,PHI:5586,UniProt,Q9I4X2,GenBank,AE004532_10,,,PAO1,pqsB,,,,,,PHI:5585,287,Pseudomonas aeruginosa,208964,PAO1,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,quinolone production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26788419,PubMed,10.7717/peerj.1495,PeerJ. 2016 Jan 7;4:e1495,zhangym@musc.edu,"The reduction in virulence of the pqsAB mutant was attributed to the complete loss of quinolone production, while production of DHQ in the pqsB and pqsC mutant maintained pathogenicity towards the nematodes.",J D Gruber 2016,2016,3 genes,"Gruber-2016-The role of 2,4-dihydroxyquinoline",BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7728,PHI:5586,UniProt,Q9I4X2,GenBank,AE004532_10,,,PAO1,pqsB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,quinolone production,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26788419,PubMed,10.7717/peerj.1495,PeerJ. 2016 Jan 7;4:e1495,zhangym@musc.edu,"The reduction in virulence of the pqsAB mutant was attributed to the complete loss of quinolone production, while production of DHQ in the pqsB and pqsC mutant maintained pathogenicity towards the nematodes.",J D Gruber 2016,2016,3 genes,"Gruber-2016-The role of 2,4-dihydroxyquinoline",BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7729,PHI:5587,UniProt,A0A0C6EZ24,GenBank,ALE49878,,,PA1RG,pqsC,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,quinolone production,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26788419,PubMed,10.7717/peerj.1495,PeerJ. 2016 Jan 7;4:e1495,zhangym@musc.edu,"The reduction in virulence of the pqsAB mutant was attributed to the complete loss of quinolone production, while production of DHQ in the pqsB and pqsC mutant maintained pathogenicity towards the nematodes.",J D Gruber 2016,2016,3 genes,"Gruber-2016-The role of 2,4-dihydroxyquinoline",BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7730,PHI:5588,UniProt,Q70Q35,GenBank,CAD88591,,,SAS 56,bcsod1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Ailsa Craig,,,,Cu-Zn-superoxide dismutase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26780422,PubMed,10.1111/mpp.12370,Mol Plant Pathol. 2016 Jan 18,carmen.gonzalez@uv.es,,L Jaime 2016,2016,1 gene,Lopez-Cruz-2016-Absence of Cu-Zn-superoxide di,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7731,PHI:5588,UniProt,Q70Q35,GenBank,CAD88591,,,SAS 56,bcsod1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),CS70000 germplasm,,,,Cu-Zn-superoxide dismutase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26780422,PubMed,10.1111/mpp.12370,Mol Plant Pathol. 2016 Jan 18,carmen.gonzalez@uv.es,,L Jaime 2016,2016,1 gene,Lopez-Cruz-2016-Absence of Cu-Zn-superoxide di,BATCH_057B,2016-03-01,MC,,,,,,,,,,,,,
,,Record 7732,PHI:5589,UniProt,G4MZE0,Ensembl Genomes,MGG_04387,,,70-15,FZC1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7733,PHI:5589,UniProt,G4MZE0,Ensembl Genomes,MGG_04387,,,70-15,FZC1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7734,PHI:5590,UniProt,G4MSY4,Ensembl Genomes,MGG_01486,,,70-15,FZC2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7735,PHI:5590,UniProt,G4MSY4,Ensembl Genomes,MGG_01486,,,70-15,FZC2,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7736,PHI:5591,UniProt,G4MT25,Ensembl Genomes,MGG_01518,,,70-15,MoNIT4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7737,PHI:5591,UniProt,G4MT25,Ensembl Genomes,MGG_01518,,,70-15,MoNIT4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7738,PHI:5592,UniProt,G4MUB7,Ensembl Genomes,MGG_01624,,,70-15,FZC3,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7739,PHI:5592,UniProt,G4MUB7,Ensembl Genomes,MGG_01624,,,70-15,FZC3,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7740,PHI:5593,UniProt,G4MVA4,Ensembl Genomes,MGG_01734,,,70-15,FZC4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7741,PHI:5593,UniProt,G4MVA4,Ensembl Genomes,MGG_01734,,,70-15,FZC4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7742,PHI:5594,UniProt,G4MW86,Ensembl Genomes,MGG_01833,,,70-15,FZC5,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7743,PHI:5594,UniProt,G4MW86,Ensembl Genomes,MGG_01833,,,70-15,FZC5,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7744,PHI:5595,UniProt,G4MR05,Ensembl Genomes,MGG_02377,,,70-15,FZC6,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7745,PHI:5595,UniProt,G4MR05,Ensembl Genomes,MGG_02377,,,70-15,FZC6,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,increased,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7746,PHI:5596,UniProt,G4NJP4,Ensembl Genomes,MGG_02595,,,70-15,FZC7,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7747,PHI:5596,UniProt,G4NJP4,Ensembl Genomes,MGG_02595,,,70-15,FZC7,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7748,PHI:5597,UniProt,G4NLQ6,Ensembl Genomes,MGG_02879,,,70-15,FZC8,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7749,PHI:5597,UniProt,G4NLQ6,Ensembl Genomes,MGG_02879,,,70-15,FZC8,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7750,PHI:5598,UniProt,G5EH28,Ensembl Genomes,MGG_02880,,,70-15,FZC9,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7751,PHI:5598,UniProt,G5EH28,Ensembl Genomes,MGG_02880,,,70-15,FZC9,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7752,PHI:5599,UniProt,G4N897,Ensembl Genomes,MGG_03463,,,70-15,FZC10,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7753,PHI:5599,UniProt,G4N897,Ensembl Genomes,MGG_03463,,,70-15,FZC10,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7754,PHI:5600,UniProt,G4NIV0,Ensembl Genomes,MGG_04108,,,70-15,TAS1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7755,PHI:5600,UniProt,G4NIV0,Ensembl Genomes,MGG_04108,,,70-15,TAS1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7756,PHI:5601,UniProt,G4N2A1,Ensembl Genomes,MGG_04843,,,70-15,FZC11,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7757,PHI:5601,UniProt,G4N2A1,Ensembl Genomes,MGG_04843,,,70-15,FZC11,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7758,PHI:5602,UniProt,G4N3M5,Ensembl Genomes,MGG_05829,,,70-15,FZC12,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7759,PHI:5602,UniProt,G4N3M5,Ensembl Genomes,MGG_05829,,,70-15,FZC12,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7760,PHI:5603,UniProt,G4N3Y8,Ensembl Genomes,MGG_05891,,,70-15,FZC13,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7761,PHI:5603,UniProt,G4N3Y8,Ensembl Genomes,MGG_05891,,,70-15,FZC13,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7762,PHI:5604,UniProt,G4N7V2,Ensembl Genomes,MGG_06355,,,70-15,FZC14,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7763,PHI:5604,UniProt,G4N7V2,Ensembl Genomes,MGG_06355,,,70-15,FZC14,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7764,PHI:5605,UniProt,G4MZS3,Ensembl Genomes,MGG_07063,,,70-15,GCC1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7765,PHI:5605,UniProt,G4MZS3,Ensembl Genomes,MGG_07063,,,70-15,GCC1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7766,PHI:5606,UniProt,G4N134,Ensembl Genomes,MGG_07800,,,70-15,FZC15,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7767,PHI:5606,UniProt,G4N134,Ensembl Genomes,MGG_07800,,,70-15,FZC15,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7768,PHI:5607,UniProt,G4MYA7,Ensembl Genomes,MGG_08094,,,70-15,FZC16,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7769,PHI:5607,UniProt,G4MYA7,Ensembl Genomes,MGG_08094,,,70-15,FZC16,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7770,PHI:5608,UniProt,G4MYQ4,Ensembl Genomes,MGG_08130,,,70-15,FZC17,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7771,PHI:5608,UniProt,G4MYQ4,Ensembl Genomes,MGG_08130,,,70-15,FZC17,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7772,PHI:5609,UniProt,G4NFM3,Ensembl Genomes,MGG_08777,,,70-15,FZC18,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7773,PHI:5609,UniProt,G4NFM3,Ensembl Genomes,MGG_08777,,,70-15,FZC18,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7774,PHI:5610,UniProt,G4MUP7,Ensembl Genomes,MGG_10197,,,70-15,TRA1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7775,PHI:5610,UniProt,G4MUP7,Ensembl Genomes,MGG_10197,,,70-15,TRA1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7776,PHI:5611,UniProt,G4MWP0,Ensembl Genomes,MGG_11116,,,70-15,FZC19,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7777,PHI:5611,UniProt,G4MWP0,Ensembl Genomes,MGG_11116,,,70-15,FZC19,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7778,PHI:5612,UniProt,G4NHT5,Ensembl Genomes,MGG_12037,,,70-15,FZC20,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7779,PHI:5612,UniProt,G4NHT5,Ensembl Genomes,MGG_12037,,,70-15,FZC20,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7780,PHI:5613,UniProt,G4MVI2,Ensembl Genomes,MGG_12424,,,70-15,FZC21,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7781,PHI:5613,UniProt,G4MVI2,Ensembl Genomes,MGG_12424,,,70-15,FZC21,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7782,PHI:5614,UniProt,G4MP35,Ensembl Genomes,MGG_16444,,,70-15,FZC22,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7783,PHI:5614,UniProt,G4MP35,Ensembl Genomes,MGG_16444,,,70-15,FZC22,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7784,PHI:5615,UniProt,G4N586,Ensembl Genomes,MGG_16756,,,70-15,FZC23,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7785,PHI:5615,UniProt,G4N586,Ensembl Genomes,MGG_16756,,,70-15,FZC23,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7786,PHI:5616,UniProt,G4N748,Ensembl Genomes,MGG_17060,,,70-15,FZC24,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7787,PHI:5616,UniProt,G4N748,Ensembl Genomes,MGG_17060,,,70-15,FZC24,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7788,PHI:5617,UniProt,G4NF77,Ensembl Genomes,MGG_17669,,,70-15,FZC25,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7789,PHI:5617,UniProt,G4NF77,Ensembl Genomes,MGG_17669,,,70-15,FZC25,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7790,PHI:5618,UniProt,G4NI99,Ensembl Genomes,MGG_17821,,,70-15,FZC26,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7791,PHI:5618,UniProt,G4NI99,Ensembl Genomes,MGG_17821,,,70-15,FZC26,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7792,PHI:5620,UniProt,G4MXR6,Ensembl Genomes,MGG_08058,,,70-15,MoACEII,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7793,PHI:5620,UniProt,G4MXR6,Ensembl Genomes,MGG_08058,,,70-15,MoACEII,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7794,PHI:5621,UniProt,G4NCY3,Ensembl Genomes,MGG_00329,,,70-15,FZC27,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7795,PHI:5621,UniProt,G4NCY3,Ensembl Genomes,MGG_00329,,,70-15,FZC27,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7796,PHI:5622,UniProt,G4N3D8,Ensembl Genomes,MGG_07681,,,70-15,FZC28,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7797,PHI:5622,UniProt,G4N3D8,Ensembl Genomes,MGG_07681,,,70-15,FZC28,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7798,PHI:5623,UniProt,G4MVR0,Ensembl Genomes,MGG_01779,,,70-15,FZC29,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7799,PHI:5623,UniProt,G4MVR0,Ensembl Genomes,MGG_01779,,,70-15,FZC29,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7800,PHI:5624,UniProt,G4MWP4,Ensembl Genomes,MGG_01887,,,70-15,FZC30,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7801,PHI:5624,UniProt,G4MWP4,Ensembl Genomes,MGG_01887,,,70-15,FZC30,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,wild type,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7802,PHI:5625,UniProt,G4NLS4,Ensembl Genomes,MGG_02866,,,70-15,FZC31,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7803,PHI:5625,UniProt,G4NLS4,Ensembl Genomes,MGG_02866,,,70-15,FZC31,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7804,PHI:5626,UniProt,G4MTB7,Ensembl Genomes,MGG_04674,,,70-15,FZC32,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7805,PHI:5626,UniProt,G4MTB7,Ensembl Genomes,MGG_04674,,,70-15,FZC32,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,wild type,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7806,PHI:5627,UniProt,G4N3W1,Ensembl Genomes,MGG_05033,,,70-15,FZC33,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7807,PHI:5627,UniProt,G4N3W1,Ensembl Genomes,MGG_05033,,,70-15,FZC33,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7808,PHI:5629,UniProt,G4N8E3,Ensembl Genomes,MGG_06279,,,70-15,FZC34,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7809,PHI:5629,UniProt,G4N8E3,Ensembl Genomes,MGG_06279,,,70-15,FZC34,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7810,PHI:5630,UniProt,G4N853,Ensembl Genomes,MGG_06312,,,70-15,FZC35,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7811,PHI:5630,UniProt,G4N853,Ensembl Genomes,MGG_06312,,,70-15,FZC35,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,increased,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7812,PHI:5631,UniProt,G4N7H6,Ensembl Genomes,MGG_06416,,,70-15,FZC36,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7813,PHI:5631,UniProt,G4N7H6,Ensembl Genomes,MGG_06416,,,70-15,FZC36,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7814,PHI:5632,UniProt,G4N606,Ensembl Genomes,MGG_06626,,,70-15,FZC37,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7815,PHI:5632,UniProt,G4N606,Ensembl Genomes,MGG_06626,,,70-15,FZC37,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7816,PHI:5633,UniProt,G4MLZ9,Ensembl Genomes,MGG_06778,,,70-15,FZC38,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7817,PHI:5633,UniProt,G4MLZ9,Ensembl Genomes,MGG_06778,,,70-15,FZC38,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,increased,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7818,PHI:5634,UniProt,G4MM49,Ensembl Genomes,MGG_06832,,,70-15,FZC39,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7819,PHI:5634,UniProt,G4MM49,Ensembl Genomes,MGG_06832,,,70-15,FZC39,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7820,PHI:5635,UniProt,G4MNH3,Ensembl Genomes,MGG_06954,,,70-15,FZC40,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7821,PHI:5635,UniProt,G4MNH3,Ensembl Genomes,MGG_06954,,,70-15,FZC40,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7822,PHI:5637,UniProt,G4MU22,Ensembl Genomes,MGG_07215,,,70-15,PIG1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7823,PHI:5637,UniProt,G4MU22,Ensembl Genomes,MGG_07215,,,70-15,PIG1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7824,PHI:5638,UniProt,G4N224,Ensembl Genomes,MGG_07534,,,70-15,FZC41,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7825,PHI:5638,UniProt,G4N224,Ensembl Genomes,MGG_07534,,,70-15,FZC41,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7826,PHI:5639,UniProt,G4N240,Ensembl Genomes,MGG_07549,,,70-15,FZC42,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7827,PHI:5639,UniProt,G4N240,Ensembl Genomes,MGG_07549,,,70-15,FZC42,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7828,PHI:5640,UniProt,G4N111,Ensembl Genomes,MGG_07777,,,70-15,FZC43,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7829,PHI:5640,UniProt,G4N111,Ensembl Genomes,MGG_07777,,,70-15,FZC43,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7830,PHI:5641,UniProt,G4N1K5,Ensembl Genomes,MGG_07845,,,70-15,FZC44,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7831,PHI:5641,UniProt,G4N1K5,Ensembl Genomes,MGG_07845,,,70-15,FZC44,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7832,PHI:5642,UniProt,G4MZ81,Ensembl Genomes,MGG_08185,,,70-15,FZC45,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7833,PHI:5642,UniProt,G4MZ81,Ensembl Genomes,MGG_08185,,,70-15,FZC45,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7834,PHI:5643,UniProt,G4MWV1,Ensembl Genomes,MGG_08314,,,70-15,FZC46,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7835,PHI:5643,UniProt,G4MWV1,Ensembl Genomes,MGG_08314,,,70-15,FZC46,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7836,PHI:5644,UniProt,G4NFL5,Ensembl Genomes,MGG_08784,,,70-15,FZC47,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7837,PHI:5644,UniProt,G4NFL5,Ensembl Genomes,MGG_08784,,,70-15,FZC47,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7838,PHI:5645,UniProt,G4MYI3,Ensembl Genomes,MGG_14728,,,70-15,FZC48,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7839,PHI:5645,UniProt,G4MYI3,Ensembl Genomes,MGG_14728,,,70-15,FZC48,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7840,PHI:5646,UniProt,G4NKD0,Ensembl Genomes,MGG_09027,,,70-15,FZC49,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7841,PHI:5646,UniProt,G4NKD0,Ensembl Genomes,MGG_09027,,,70-15,FZC49,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7842,PHI:5647,UniProt,G4MQA4,Ensembl Genomes,MGG_09273,,,70-15,FZC50,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7843,PHI:5647,UniProt,G4MQA4,Ensembl Genomes,MGG_09273,,,70-15,FZC50,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7844,PHI:5648,UniProt,G4MQR5,Ensembl Genomes,MGG_09312,,,70-15,FZC51,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7845,PHI:5648,UniProt,G4MQR5,Ensembl Genomes,MGG_09312,,,70-15,FZC51,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7846,PHI:5649,UniProt,G4NKX6,Ensembl Genomes,MGG_09676,,,70-15,FZC52,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7847,PHI:5649,UniProt,G4NKX6,Ensembl Genomes,MGG_09676,,,70-15,FZC52,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7848,PHI:5650,UniProt,G4NII4,Ensembl Genomes,MGG_09829,,,70-15,FZC53,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7849,PHI:5650,UniProt,G4NII4,Ensembl Genomes,MGG_09829,,,70-15,FZC53,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,increased,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7850,PHI:5651,UniProt,G4MRM4,Ensembl Genomes,MGG_09950,,,70-15,FZC54,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7851,PHI:5651,UniProt,G4MRM4,Ensembl Genomes,MGG_09950,,,70-15,FZC54,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,increased,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7852,PHI:5652,UniProt,G4MPR7,Ensembl Genomes,MGG_11764,,,70-15,FZC55,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7853,PHI:5652,UniProt,G4MPR7,Ensembl Genomes,MGG_11764,,,70-15,FZC55,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7854,PHI:5653,UniProt,G4N5Y8,Ensembl Genomes,MGG_12776,,,70-15,FZC56,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7855,PHI:5653,UniProt,G4N5Y8,Ensembl Genomes,MGG_12776,,,70-15,FZC56,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7856,PHI:5654,UniProt,G4N093,Ensembl Genomes,MGG_13350,,,70-15,FZC57,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7857,PHI:5654,UniProt,G4N093,Ensembl Genomes,MGG_13350,,,70-15,FZC57,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7858,PHI:5655,UniProt,G4N0A5,Ensembl Genomes,MGG_13360,,,70-15,CNF3,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7859,PHI:5655,UniProt,G4N0A5,Ensembl Genomes,MGG_13360,,,70-15,CNF3,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,wild type,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7860,PHI:5656,UniProt,G4N0R9,Ensembl Genomes,MGG_13385,,,70-15,FZC58,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7861,PHI:5656,UniProt,G4N0R9,Ensembl Genomes,MGG_13385,,,70-15,FZC58,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7862,PHI:5657,UniProt,G4N9M9,Ensembl Genomes,MGG_13629,,,70-15,FZC59,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7863,PHI:5657,UniProt,G4N9M9,Ensembl Genomes,MGG_13629,,,70-15,FZC59,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7864,PHI:5658,,no data found,Ensembl Genomes,MGG_14175,,,70-15,FZC60,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7865,PHI:5658,,no data found,Ensembl Genomes,MGG_14175,,,70-15,FZC60,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7866,PHI:5659,UniProt,G4N6W1,Ensembl Genomes,MGG_14852,,,70-15,FZC61,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7867,PHI:5659,UniProt,G4N6W1,Ensembl Genomes,MGG_14852,,,70-15,FZC61,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7868,PHI:5661,UniProt,G4NGB1,Ensembl Genomes,MGG_17623,,,70-15,PCF1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,reduced virulence,,,,,,reduced,increased,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7869,PHI:5662,UniProt,G4NF22,Ensembl Genomes,MGG_00021,,,70-15,FZC62,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7870,PHI:5662,UniProt,G4NF22,Ensembl Genomes,MGG_00021,,,70-15,FZC62,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7871,PHI:5663,UniProt,G4NEI3,Ensembl Genomes,MGG_00096,,,70-15,FZC63,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7872,PHI:5663,UniProt,G4NEI3,Ensembl Genomes,MGG_00096,,,70-15,FZC63,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7873,PHI:5664,UniProt,G4NCZ2,Ensembl Genomes,MGG_00320,,,70-15,FZC64,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7874,PHI:5664,UniProt,G4NCZ2,Ensembl Genomes,MGG_00320,,,70-15,FZC64,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7875,PHI:5665,UniProt,G4NCC3,Ensembl Genomes,MGG_00417,,,70-15,FZC65,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7876,PHI:5665,UniProt,G4NCC3,Ensembl Genomes,MGG_00417,,,70-15,FZC65,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7877,PHI:5666,UniProt,G4NBS6,Ensembl Genomes,MGG_00494,,,70-15,MoPRO1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7878,PHI:5666,UniProt,G4NBS6,Ensembl Genomes,MGG_00494,,,70-15,MoPRO1,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7879,PHI:5667,UniProt,G4MNC4,Ensembl Genomes,MGG_02089,,,70-15,FZC66,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7880,PHI:5667,UniProt,G4MNC4,Ensembl Genomes,MGG_02089,,,70-15,FZC66,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,wild type,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7881,PHI:5668,UniProt,G4MQ49,Ensembl Genomes,MGG_02289,,,70-15,FZC67,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7882,PHI:5668,UniProt,G4MQ49,Ensembl Genomes,MGG_02289,,,70-15,FZC67,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7883,PHI:5670,UniProt,G4NAE2,Ensembl Genomes,MGG_03183,,,70-15,CNF4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7884,PHI:5670,UniProt,G4NAE2,Ensembl Genomes,MGG_03183,,,70-15,CNF4,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,wild type,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7885,PHI:5671,UniProt,G4N6T1,Ensembl Genomes,MGG_03669,,,70-15,FZC68,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7886,PHI:5671,UniProt,G4N6T1,Ensembl Genomes,MGG_03669,,,70-15,FZC68,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7887,PHI:5672,UniProt,G4NIQ8,Ensembl Genomes,MGG_04141,,,70-15,FZC69,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7888,PHI:5672,UniProt,G4NIQ8,Ensembl Genomes,MGG_04141,,,70-15,FZC69,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7889,PHI:5673,UniProt,G4NGF7,Ensembl Genomes,MGG_04326,,,70-15,FZC70,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7890,PHI:5673,UniProt,G4NGF7,Ensembl Genomes,MGG_04326,,,70-15,FZC70,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7891,PHI:5674,UniProt,G4MZ03,Ensembl Genomes,MGG_04360,,,70-15,FZC71,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7892,PHI:5674,UniProt,G4MZ03,Ensembl Genomes,MGG_04360,,,70-15,FZC71,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7893,PHI:5675,UniProt,G4N362,Ensembl Genomes,MGG_04933,,,70-15,FZC72,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7894,PHI:5675,UniProt,G4N362,Ensembl Genomes,MGG_04933,,,70-15,FZC72,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7895,PHI:5676,UniProt,G4N4R4,Ensembl Genomes,MGG_05153,,,70-15,FZC73,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7896,PHI:5676,UniProt,G4N4R4,Ensembl Genomes,MGG_05153,,,70-15,FZC73,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7897,PHI:5678,UniProt,G4MPH6,Ensembl Genomes,MGG_05724,,,70-15,FZC74,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7898,PHI:5678,UniProt,G4MPH6,Ensembl Genomes,MGG_05724,,,70-15,FZC74,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7899,PHI:5679,UniProt,G4N3N6,Ensembl Genomes,MGG_05845,,,70-15,FZC75,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7900,PHI:5679,UniProt,G4N3N6,Ensembl Genomes,MGG_05845,,,70-15,FZC75,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7901,PHI:5680,UniProt,G4N8I4,Ensembl Genomes,MGG_06243,,,70-15,FZC76,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7902,PHI:5680,UniProt,G4N8I4,Ensembl Genomes,MGG_06243,,,70-15,FZC76,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,wild type,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7903,PHI:5681,UniProt,G4N782,Ensembl Genomes,MGG_06455,,,70-15,FZC77,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7904,PHI:5681,UniProt,G4N782,Ensembl Genomes,MGG_06455,,,70-15,FZC77,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7905,PHI:5682,UniProt,G4N170,Ensembl Genomes,MGG_07458,,,70-15,FZC78,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7906,PHI:5682,UniProt,G4N170,Ensembl Genomes,MGG_07458,,,70-15,FZC78,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7907,PHI:5683,UniProt,G4N2Z7,Ensembl Genomes,MGG_07636,,,70-15,FZC79,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7908,PHI:5683,UniProt,G4N2Z7,Ensembl Genomes,MGG_07636,,,70-15,FZC79,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7909,PHI:5684,UniProt,G4MWD3,Ensembl Genomes,MGG_08361,,,70-15,FZC80,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7910,PHI:5684,UniProt,G4MWD3,Ensembl Genomes,MGG_08361,,,70-15,FZC80,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7911,PHI:5685,UniProt,G4MWF8,Ensembl Genomes,MGG_08974,,,70-15,FZC81,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7912,PHI:5685,UniProt,G4MWF8,Ensembl Genomes,MGG_08974,,,70-15,FZC81,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,increased,wild type,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7913,PHI:5686,UniProt,G4MSQ8,Ensembl Genomes,MGG_12339,,,70-15,FZC82,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7914,PHI:5686,UniProt,G4MSQ8,Ensembl Genomes,MGG_12339,,,70-15,FZC82,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7915,PHI:5688,UniProt,G4N2V8,Ensembl Genomes,MGG_13927,,,70-15,FZC83,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7916,PHI:5688,UniProt,G4N2V8,Ensembl Genomes,MGG_13927,,,70-15,FZC83,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,wild type,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7917,PHI:5689,UniProt,G4NAW7,Ensembl Genomes,MGG_14816,,,70-15,FZC84,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7918,PHI:5689,UniProt,G4NAW7,Ensembl Genomes,MGG_14816,,,70-15,FZC84,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7919,PHI:5690,UniProt,G4N532,Ensembl Genomes,MGG_15139,,,70-15,FZC85,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7920,PHI:5690,UniProt,G4N532,Ensembl Genomes,MGG_15139,,,70-15,FZC85,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,increased,increased,reduced,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7921,PHI:5691,UniProt,G4NA57,Ensembl Genomes,MGG_17012,,,70-15,FZC86,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7922,PHI:5691,UniProt,G4NA57,Ensembl Genomes,MGG_17012,,,70-15,FZC86,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,reduced,reduced,increased,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7923,PHI:5692,UniProt,G4N6I1,Ensembl Genomes,MGG_03711,,,70-15,FZC87,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7924,PHI:5692,UniProt,G4N6I1,Ensembl Genomes,MGG_03711,,,70-15,FZC87,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,,increased,reduced,reduced,increased,no,,,,,,,gene deletion: full,,,MU,25299517,PubMed,10.1371/journal.ppat.1004432,,jplu@zju.edu.cn,leaf: detached,J Lu 2014,2014,High-throughput gene knockout study,,,2016-05-01,RRes,Fucheng Lin,,,,,,,,,,,,
,,Record 7925,PHI:6067,UniProt,Q4TVQ0,GenBank,AAY54617,,,10403S,PrfA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: chemical inhibition,,,RP,26991105,PubMed,10.1016/j.chembiol.2016.02.013,Cell Chem Biol. 2016 Mar 17;23(3):404-14,jorgen.johansson@umu.se,"Ring-fused 2-pyridones inhibit transcriptional regulator PrfA, thus leading to reduced expression on several virulence genes and attenuated virulence.",J A D Good 2016,2016,1 gene,Good-2016-Attenuating Listeria monocytogenes V,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7926,PHI:6068,UniProt,Q99078,GenBank,AAA62242,,,FBD12,fuz7,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf,dual specificity protein kinase,,,MAPK pathway,loss of pathogenicity,yes,yes,,,,,,,,no,,,,,,,gene mutation,,,RP,14665454,PubMed,10.1128/EC.2.6.1187-1199.2003,Eukaryot Cell. 2003 Dec;2(6):1187-99,Kahmann@staff.uni-marburg.de,,P Muller 2003,2003,2 genes,Muller-2003-Mating and pathogenic development,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7927,PHI:6069,UniProt,Q8J230,GenBank,AAN63948,,,RK32 a1b3,kpp4,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf,MAPKK kinase,,,MAPK pathway,loss of pathogenicity,yes,yes,,,,,,,,no,,,,,,,gene mutation,,,RP,14665454,PubMed,10.1128/EC.2.6.1187-1199.2003,Eukaryot Cell. 2003 Dec;2(6):1187-99,Kahmann@staff.uni-marburg.de,,P Muller 2003,2003,2 genes,Muller-2003-Mating and pathogenic development,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7928,PHI:6070,,no data found,Ensembl Genomes,um00133,,,,lip1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf,encodes phospholipase A2,,,,unaffected pathogenicity,no,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26950180,PubMed,10.1111/mpp.12391,Mol Plant Pathol. 2016 Mar 7,kronstad@msl.ubc.ca,lip2 mutants were sensitive to oxidative stress provoked by hydrogen peroxide and by increased production ofreactive oxygen species caused by inhibitors of mitochondrial functions.,S C Lambie 2016,2016,2 genes,Lambie-2016-The putative phospholipase Lip2 co,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7929,PHI:6071,,no data found,Ensembl Genomes,um01927,,,,lip2,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf,encodes phospholipase A2,,,,reduced virulence,no,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26950180,PubMed,10.1111/mpp.12391,Mol Plant Pathol. 2016 Mar 7,kronstad@msl.ubc.ca,lip2 mutants were sensitive to oxidative stress provoked by hydrogen peroxide and by increased production ofreactive oxygen species caused by inhibitors of mitochondrial functions.,S C Lambie 2016,2016,2 genes,Lambie-2016-The putative phospholipase Lip2 co,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7930,PHI:6070,,no data found,Ensembl Genomes,um00133,,,,lip1,,,,,,PHI:6071,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf,encodes phospholipase A2,,,,reduced virulence,no,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26950180,PubMed,10.1111/mpp.12391,Mol Plant Pathol. 2016 Mar 7,kronstad@msl.ubc.ca,lip2 mutants were sensitive to oxidative stress provoked by hydrogen peroxide and by increased production ofreactive oxygen species caused by inhibitors of mitochondrial functions.,S C Lambie 2016,2016,2 genes,Lambie-2016-The putative phospholipase Lip2 co,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7931,PHI:6071,,no data found,Ensembl Genomes,um01927,,,,lip2,,,,,,PHI:6070,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,leaf,encodes phospholipase A2,,,,reduced virulence,no,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26950180,PubMed,10.1111/mpp.12391,Mol Plant Pathol. 2016 Mar 7,kronstad@msl.ubc.ca,lip2 mutants were sensitive to oxidative stress provoked by hydrogen peroxide and by increased production ofreactive oxygen species caused by inhibitors of mitochondrial functions.,S C Lambie 2016,2016,2 genes,Lambie-2016-The putative phospholipase Lip2 co,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7932,PHI:6072,UniProt,A4VT78,GenBank,ABP89317,,,05ZYH33,CodY,,,,,,,1307,Streptococcus suis,,SC19,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; lung; heart; brain,global regulatory protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,RP,26883762,PubMed,10.1038/srep21241,Sci Rep. 2016 Feb 17;6:21241,beiwc@mail.hzau.edu.cn,The codY mutation inhibited the adherence and invasion ability of S. Suis 2.,L Feng 2016,2016,1 gene,Feng-2016-The CodY regulator is essential for,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7933,PHI:6073,UniProt,A0A0H3LBW1,GenBank,BAL65115,,,Erdman,PE11,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,saprophytic,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,PE/PPE family protein,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,SDS; H2O2; ethambutol; isoniazid; rifampicin; vancomycin; ampicillin,SDS: CHEBI:8984; H2O2: CHEBI:16240; ethambutol: CHEBI:4877; isoniazid: CHEBI:6030; rifampicin: CHEBI:28077; vancomycin: CHEBI:28001; ampicillin: CHEBI:28971,,,,,functional test in host: transient expression,,,RP,26902658,PubMed,10.1038/srep21624,Sci Rep. 2016 Feb 23;6:21624,sangita@cdfd.org,M. Smegmatis expressing PE11 (Msmeg-PE11) exhibited altered colony morphology and cell wall lipid composition leading to a marked increase in resistance against various environmental stressors and antibiotics.,P Singh 2016,2016,1 gene,"Singh-2016-PE11, a PE_PPE family protein of My",BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7934,PHI:6074,UniProt,Q5ADN1,GenBank,EAL00917,,,SC5314,Tpd3,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,PP2A family of phosphatases,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,Congo red; calcoflour white; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,RP,26991697,PubMed,10.1111/mmi.13376,Mol Microbiol. 2016 Mar 16,jlsang@bnu.edu.cn,,Q Liu 2016,2016,1 gene,Liu-2016-Tpd3-Pph21 phosphatase plays a direct,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7935,PHI:6075,UniProt,G8BJ74,GenBank,CCE44689,,,CDC317,och1,,,,,,,5480,Candida parapsilosis,,CLIB 214,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney; spleen,"alpha1,6-mannosyltransferase",,,,reduced virulence,,,,,,,,reduced; aberrant,,no,calcofluor white; Congo red; tunicamycin; SDS; hygromycin B; vanadate; NaCl; KCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; NaCl: CHEBI:26710; SDS: CHEBI:8984; tunicamycin: CHEBI:29699; hygromycin B: CHEBI:16976; vanadate: CHEBI:46442; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,RP,27014229,PubMed,10.3389/fmicb.2016.00306,Front Microbiol. 2016 Mar 8;7:306,gacsera@gmail.com,,L A Pérez-García 2016,2016,1 gene,Perez-Garcia-2016-Role of Protein Glycosylatio,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7936,PHI:6076,UniProt,Q5A5Q8,GenBank,EAK98088,,,SC5314,RPS41,,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,cytoplasmic ribosomal protein,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26952720,PubMed,10.1007/s00284-016-1019-7,Curr Microbiol. 2016 Mar 7,caoyingying608@163.com,,H Lu 2016,2016,1 gene,"Lu-2016-Roles of RPS41 in Biofilm Formation, V",BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7937,PHI:6077,UniProt,P87034,GenBank,AAC49726,,,FB1,gpa3,,,,,,,5270,Ustilago maydis,559306,FB1,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,galpha subunit,,,cAMP pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,11043465,PubMed,10.1094/MPMI.2000.13.10.1034,Mol Plant Microbe Interact. 2000 Oct;13(10):1034-40.,R.Kahmann@lrz.uni-muenchen.de,,J Krüger 2000,2000,2 genes,Kruger-2000-Activation of the cAMP pathway in,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7938,PHI:6078,UniProt,P49605,GenBank,AAA57470,,,518,ubc1,,,,,,,5270,Ustilago maydis,559306,FB1,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,adenylate cyclase,,,cAMP pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,11043465,PubMed,10.1094/MPMI.2000.13.10.1034,Mol Plant Microbe Interact. 2000 Oct;13(10):1034-40.,R.Kahmann@lrz.uni-muenchen.de,,J Krüger 2000,2000,2 genes,Kruger-2000-Activation of the cAMP pathway in,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7939,PHI:6079,UniProt,Q5AGC4,GenBank,EAL01727,,,SC5314,Ecm33,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,cell surface GPI-anchored protein,,,,reduced virulence,,,,,,,,,,no,sorbitol; KCl; NaCl; caffeine; diamide; menadione; rapamycin; H2O2,"H2O2: CHEBI:16240; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; menadione: CHEBI:28869; rapamycin: CHEBI:9168; l,  caffeine: CHEBI:27732",,,,,gene mutation,,,RP,26870022,PubMed,10.3389/fmicb.2016.00064,Front Microbiol. 2016 Feb 2;7:64,uciamon@ucm.es,,A Gil-Bona 2016,2016,1 gene,Gil-Bona-2016-The Cell Wall Protein Ecm33 of C,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7940,PHI:6080,UniProt,Q9HV59,GenBank,AE004888_1,,,PAO1,pnp,,,,,,,287,Pseudomonas aeruginosa,1009714,PAK,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,PNPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26973625,PubMed,10.3389/fmicb.2016.00247,Front Microbiol. 2016 Mar 2;7:247,wuweihui@nankai.edu.cn,Pseudomonas aeruginosa the KH-S1 domains of PNPase are required for the type III secretion system (T3SS) and bacterial virulence.,R Chen 2016,2016,1 gene,Chen-2016-Polynucleotide Phosphorylase Regulat,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7941,PHI:6081,UniProt,G0ZS89,GenBank,AEL88503,,,,MoCps1,,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,acyl-CoA-ligase,,,,reduced virulence,,yes,yes,yes,,,,,,no,calcofluor white; Congo red; NaCl; SDS; sorbitol,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; NaCl: CHEBI:26710; SDS: CHEBI:8984; sorbitol: CHEBI:17924,,,,,gene deletion: full; gene complementation,,,RP,26979515,PubMed,10.1007/s00294-016-0593-3,Curr Genet. 2016 Mar 15,yangj@cau.edu.cn,,Y Wang 2016,2016,1 gene,Wang-2016-MoCps1 is important for conidiation,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7942,PHI:6082,,no data found,,,,,,MoHEG13,,,,,,,318829,Magnaporthe oryzae,,Ina72,blast (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26883226,PubMed,10.1007/s00299-016-1943-9,Plant Cell Rep. 2016 Feb 16,schaffrath@bio3.rwth-aachen.de,,V Mogga 2016,2016,2 genes,Mogga-2016-Magnaporthe oryzae effectors MoHEG1,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7943,PHI:6083,,no data found,,,,,,MoHEG16,,,,,,,318829,Magnaporthe oryzae,,Ina72,blast (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26883226,PubMed,10.1007/s00299-016-1943-9,Plant Cell Rep. 2016 Feb 16,schaffrath@bio3.rwth-aachen.de,,V Mogga 2016,2016,2 genes,Mogga-2016-Magnaporthe oryzae effectors MoHEG1,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7944,PHI:6084,UniProt,Q4WSF6,GenBank,CAD28436,,,Af293,sakA,,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,MAPkinase,,,HOG pathway,reduced virulence,,,,,,,,,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS); caspofungin; nikkomycin Z; fludioxonil; iprodione; H2O2; t-butyl hydroperoxide,"Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090",,,,,gene mutation,,,RP,26878695,PubMed,10.1111/mmi.13354,Mol Microbiol. 2016 Feb 15,ggoldman@usp.br,"mutants were more sensitive to osmotic and oxidative stresses, and to cell wall damaging agents.",A C M de O B Nascimento 2016,2016,2 genes,de Oliveira Bru-2016-Mitogen activated protein,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7945,PHI:6085,UniProt,Q4WUN7,GenBank,ABD64613,,,,mpkC,,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,MAPkinase,,,HOG pathway,reduced virulence,,,,,,,,,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS); caspofungin; nikkomycin Z; fludioxonil; iprodione; H2O2; t-butyl hydroperoxide,"Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090",,,,,gene mutation,,,RP,26878695,PubMed,10.1111/mmi.13354,Mol Microbiol. 2016 Feb 15,ggoldman@usp.br,"mutants were more sensitive to osmotic and oxidative stresses, and to cell wall damaging agents.",A C M de O B Nascimento 2016,2016,2 genes,de Oliveira Bru-2016-Mitogen activated protein,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7946,PHI:6084,UniProt,Q4WSF6,GenBank,CAD28436,,,Af293,sakA,,,,,,PHI:6085,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,MAPkinase,,,HOG pathway,reduced virulence,,,,,,,,,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS); caspofungin; nikkomycin Z; fludioxonil; iprodione; H2O2; t-butyl hydroperoxide,"Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090",,,,,gene mutation,,,RP,26878695,PubMed,10.1111/mmi.13354,Mol Microbiol. 2016 Feb 15,ggoldman@usp.br,"mutants were more sensitive to osmotic and oxidative stresses, and to cell wall damaging agents.",A C M de O B Nascimento 2016,2016,2 genes,de Oliveira Bru-2016-Mitogen activated protein,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7947,PHI:6085,UniProt,Q4WUN7,GenBank,ABD64613,,,,mpkC,,,,,,PHI:6084,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,MAPkinase,,,HOG pathway,reduced virulence,,,,,,,,,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS); caspofungin; nikkomycin Z; fludioxonil; iprodione; H2O2; t-butyl hydroperoxide,"Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090",,,,,gene mutation,,,RP,26878695,PubMed,10.1111/mmi.13354,Mol Microbiol. 2016 Feb 15,ggoldman@usp.br,"mutants were more sensitive to osmotic and oxidative stresses, and to cell wall damaging agents.",A C M de O B Nascimento 2016,2016,2 genes,de Oliveira Bru-2016-Mitogen activated protein,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7948,PHI:6086,UniProt,Q3BYL2,GenBank,CAJ22051,,,85-10,hpaA,,,,,,PHI:6087,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,secreted regulator,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27016569,PubMed,10.1128/AEM.00537-16,Appl Environ Microbiol. 2016 Mar 25,daniela.buettner@genetik.uni-halle.de,"Deletion of hpaA, hpaB and hpaC leads to a loss of pathogenicity but allows the translocation of fusion proteins between the HrpB2 T3S signal and effector proteins into leaves of host and non-host plants.",F Scheibner 2016,2016,3 genes,Scheibner-2016-Type III-dependent translocatio,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7949,PHI:6087,UniProt,Q9WWG3,GenBank,AAD21328,,,75-3,hpaB,,,,,,PHI:6086,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,T3S chaperone,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27016569,PubMed,10.1128/AEM.00537-16,Appl Environ Microbiol. 2016 Mar 25,daniela.buettner@genetik.uni-halle.de,"Deletion of hpaA, hpaB and hpaC leads to a loss of pathogenicity but allows the translocation of fusion proteins between the HrpB2 T3S signal and effector proteins into leaves of host and non-host plants.",F Scheibner 2016,2016,3 genes,Scheibner-2016-Type III-dependent translocatio,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7950,PHI:6086,UniProt,Q3BYL2,GenBank,CAJ22051,,,85-10,hpaA,,,,,,PHI:6088,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,secreted regulator,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27016569,PubMed,10.1128/AEM.00537-16,Appl Environ Microbiol. 2016 Mar 25,daniela.buettner@genetik.uni-halle.de,"Deletion of hpaA, hpaB and hpaC leads to a loss of pathogenicity but allows the translocation of fusion proteins between the HrpB2 T3S signal and effector proteins into leaves of host and non-host plants.",F Scheibner 2016,2016,3 genes,Scheibner-2016-Type III-dependent translocatio,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7951,PHI:6088,UniProt,Q3BYK8,GenBank,Q3BYK8_XANC5,,,85-10,hpaC,,,,,,PHI:6086,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,T3S component,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27016569,PubMed,10.1128/AEM.00537-16,Appl Environ Microbiol. 2016 Mar 25,daniela.buettner@genetik.uni-halle.de,"Deletion of hpaA, hpaB and hpaC leads to a loss of pathogenicity but allows the translocation of fusion proteins between the HrpB2 T3S signal and effector proteins into leaves of host and non-host plants.",F Scheibner 2016,2016,3 genes,Scheibner-2016-Type III-dependent translocatio,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7952,PHI:6087,UniProt,Q9WWG3,GenBank,AAD21328,,,75-3,hpaB,,,,,,PHI:6088,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,T3S chaperone,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27016569,PubMed,10.1128/AEM.00537-16,Appl Environ Microbiol. 2016 Mar 25,daniela.buettner@genetik.uni-halle.de,"Deletion of hpaA, hpaB and hpaC leads to a loss of pathogenicity but allows the translocation of fusion proteins between the HrpB2 T3S signal and effector proteins into leaves of host and non-host plants.",F Scheibner 2016,2016,3 genes,Scheibner-2016-Type III-dependent translocatio,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7953,PHI:6088,UniProt,Q3BYK8,GenBank,Q3BYK8_XANC5,,,85-10,hpaC,,,,,,PHI:6087,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,T3S component,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27016569,PubMed,10.1128/AEM.00537-16,Appl Environ Microbiol. 2016 Mar 25,daniela.buettner@genetik.uni-halle.de,"Deletion of hpaA, hpaB and hpaC leads to a loss of pathogenicity but allows the translocation of fusion proteins between the HrpB2 T3S signal and effector proteins into leaves of host and non-host plants.",F Scheibner 2016,2016,3 genes,Scheibner-2016-Type III-dependent translocatio,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7954,PHI:6086,UniProt,Q3BYL2,GenBank,CAJ22051,,,85-10,hpaA,,,,,,PHI:6087; PHI:6088,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,secreted regulator,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27016569,PubMed,10.1128/AEM.00537-16,Appl Environ Microbiol. 2016 Mar 25,daniela.buettner@genetik.uni-halle.de,"Deletion of hpaA, hpaB and hpaC leads to a loss of pathogenicity but allows the translocation of fusion proteins between the HrpB2 T3S signal and effector proteins into leaves of host and non-host plants.",F Scheibner 2016,2016,3 genes,Scheibner-2016-Type III-dependent translocatio,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7955,PHI:6087,UniProt,Q9WWG3,GenBank,AAD21328,,,75-3,hpaB,,,,,,PHI:6086; PHI:6088,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,T3S chaperone,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27016569,PubMed,10.1128/AEM.00537-16,Appl Environ Microbiol. 2016 Mar 25,daniela.buettner@genetik.uni-halle.de,"Deletion of hpaA, hpaB and hpaC leads to a loss of pathogenicity but allows the translocation of fusion proteins between the HrpB2 T3S signal and effector proteins into leaves of host and non-host plants.",F Scheibner 2016,2016,3 genes,Scheibner-2016-Type III-dependent translocatio,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7956,PHI:6088,UniProt,Q3BYK8,GenBank,Q3BYK8_XANC5,,,85-10,hpaC,,,,,,PHI:6086; PHI:6087,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,T3S component,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27016569,PubMed,10.1128/AEM.00537-16,Appl Environ Microbiol. 2016 Mar 25,daniela.buettner@genetik.uni-halle.de,"Deletion of hpaA, hpaB and hpaC leads to a loss of pathogenicity but allows the translocation of fusion proteins between the HrpB2 T3S signal and effector proteins into leaves of host and non-host plants.",F Scheibner 2016,2016,3 genes,Scheibner-2016-Type III-dependent translocatio,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7957,PHI:6089,UniProt,A0A0E2GV55,GenBank,ENV42569,,,NIPH 386,katG,,,,,,PHI:6090,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,catalase-peroxidase,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26860891,PubMed,10.1016/j.lfs.2016.02.015,Life Sci. 2016 Mar 1;148:31-40,yusen.liu@nationwidechildrens.org,Bacteria lacking both thekatGandkatEgenes exhibit the highest sensitivity to H2O2.,D Sun 2016,2016,2 genes,Sun-2016-KatG and KatE confer Acinetobacter re,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7958,PHI:6090,UniProt,A0A0R1BRS8,GenBank,KRJ72801,,,ABBL048,katE,,,,,,PHI:6091,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,hydroperoxidase,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26860891,PubMed,10.1016/j.lfs.2016.02.015,Life Sci. 2016 Mar 1;148:31-40,yusen.liu@nationwidechildrens.org,Bacteria lacking both thekatGandkatEgenes exhibit the highest sensitivity to H2O2.,D Sun 2016,2016,2 genes,Sun-2016-KatG and KatE confer Acinetobacter re,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7959,PHI:6091,UniProt,I1RG99,GenBank,ESU08237,,,PH-1,FgVps35,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,components of retromer,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26875543,PubMed,10.1111/nph.13867,New Phytol. 2016 Feb 15,yxxc19204@126.com,,W Zheng 2016,2016,5 genes,Zheng-2016-Retrograde trafficking from the end,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7960,PHI:6092,UniProt,I1RC52,GenBank,ESU06438,,,PH-1,FgVps26,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,components of retromer,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26875543,PubMed,10.1111/nph.13867,New Phytol. 2016 Feb 15,yxxc19204@126.com,,W Zheng 2016,2016,5 genes,Zheng-2016-Retrograde trafficking from the end,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7961,PHI:6093,UniProt,I1RD63,GenBank,ESU06878,,,PH-1,FgVps29,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,components of retromer,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26875543,PubMed,10.1111/nph.13867,New Phytol. 2016 Feb 15,yxxc19204@126.com,,W Zheng 2016,2016,5 genes,Zheng-2016-Retrograde trafficking from the end,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7962,PHI:6094,UniProt,I1RYY6,GenBank,ESU16206,,,PH-1,FgVps17,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,components of retromer,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26875543,PubMed,10.1111/nph.13867,New Phytol. 2016 Feb 15,yxxc19204@126.com,,W Zheng 2016,2016,5 genes,Zheng-2016-Retrograde trafficking from the end,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7963,PHI:6095,UniProt,I1REC4,GenBank,ESU07394,,,PH-1,FgVps5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,components of retromer,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,26875543,PubMed,10.1111/nph.13867,New Phytol. 2016 Feb 15,yxxc19204@126.com,,W Zheng 2016,2016,5 genes,Zheng-2016-Retrograde trafficking from the end,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7964,PHI:6096,UniProt,Q8DNW9,GenBank,AAL00295,,,R6,PepO,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),TLR2 and TLR4 deficient C57BL/6,,,lung,endopeptidase,,,TLR pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26973817,PubMed,10.3389/fcimb.2016.00023,Front Cell Infect Microbiol. 2016 Feb 29;6:23.,apoe@163.com,"TLR2 or TLR4 deficient mice subjected to rPepO treatment showed decreased cytokines production, reduced neutrophils infiltration and intensified tissue injury as compared with WT mice.",H Zhang 2016,2016,1 gene,Zhang-2016-Streptococcus pneumoniae Endopeptid,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7965,PHI:6097,UniProt,A6TAK8,GenBank,ABR77629,,,MGH 78578,hns,,,,,,,573,Klebsiella pneumoniae,,123/01,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,pleiotropic regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26904512,PubMed,10.3389/fcimb.2016.00013,Front Cell Infect Microbiol. 2016 Feb 9;6:13,miguel_angel_81@live.com,"In infection experiments using RAW264.7 and THP-1 differentiated macrophages, the hns mutant was less phagocytized than the wild-type strain.",M A Ares 2016,2016,3 genes,Ares-2016-H-NS Nucleoid Protein Controls Virul,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7966,PHI:6098,UniProt,A0A0M4UMQ8,GenBank,BAS34425,,,YH43,cps,,,,,,,573,Klebsiella pneumoniae,,123/01,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,capsular polysaccharide,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26904512,PubMed,10.3389/fcimb.2016.00013,Front Cell Infect Microbiol. 2016 Feb 9;6:13,miguel_angel_81@live.com,"In infection experiments using RAW264.7 and THP-1 differentiated macrophages, the hns mutant was less phagocytized than the wild-type strain.",M A Ares 2016,2016,3 genes,Ares-2016-H-NS Nucleoid Protein Controls Virul,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7967,PHI:6097,UniProt,A6TAK8,GenBank,ABR77629,,,MGH 78578,hns,,,,,,PHI:6098,573,Klebsiella pneumoniae,,123/01,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,pleiotropic regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26904512,PubMed,10.3389/fcimb.2016.00013,Front Cell Infect Microbiol. 2016 Feb 9;6:13,miguel_angel_81@live.com,"In infection experiments using RAW264.7 and THP-1 differentiated macrophages, the hns mutant was less phagocytized than the wild-type strain.",M A Ares 2016,2016,3 genes,Ares-2016-H-NS Nucleoid Protein Controls Virul,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7968,PHI:6098,UniProt,A0A0M4UMQ8,GenBank,BAS34425,,,YH43,cps,,,,,,PHI:6097,573,Klebsiella pneumoniae,,123/01,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,capsular polysaccharide,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26904512,PubMed,10.3389/fcimb.2016.00013,Front Cell Infect Microbiol. 2016 Feb 9;6:13,miguel_angel_81@live.com,"In infection experiments using RAW264.7 and THP-1 differentiated macrophages, the hns mutant was less phagocytized than the wild-type strain.",M A Ares 2016,2016,3 genes,Ares-2016-H-NS Nucleoid Protein Controls Virul,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7969,PHI:6099,UniProt,G3FT04,GenBank,AEO27492,,,AJ218,MrkA,,,,,,,573,Klebsiella pneumoniae,,123/01,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,ferrous iron transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26904512,PubMed,10.3389/fcimb.2016.00013,Front Cell Infect Microbiol. 2016 Feb 9;6:13,miguel_angel_81@live.com,"In infection experiments using RAW264.7 and THP-1 differentiated macrophages, the hns mutant was less phagocytized than the wild-type strain.",M A Ares 2016,2016,3 genes,Ares-2016-H-NS Nucleoid Protein Controls Virul,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7970,PHI:6100,UniProt,P31498,GenBank,AAA68488,,,YPIII,YopJ,,,,,,PHI:6101,632,Yersinia pestis,,KIM1001,bubonic plague,rodents,10090,Mus musculus (related: house mouse),B6;129S7-Dbh<tm1Rpa>/Rpa,,,spleen; lymph node,type III secretion system effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26884330,PubMed,10.1074/jbc.M115.697698,J Biol Chem. 2016 Feb 16. pii: jbc.M115.697698,egil.lien@umassmed.edu,"The reduced virulence of the YopJ-YopM mutant is dependent on the presence of IL-1beta, IL-18 and caspase-1.",D Ratner 2016,2016,2 genes,Ratner-2016-Manipulation of IL-1beta and IL-18,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7971,PHI:6101,UniProt,P17778,GenBank,AAC69806,,,KIM5,YopM,,,,,,PHI:6100,632,Yersinia pestis,,KIM1001,bubonic plague,rodents,10090,Mus musculus (related: house mouse),B6;129S7-Dbh<tm1Rpa>/Rpa,,,spleen; lymph node,type III secretion system effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26884330,PubMed,10.1074/jbc.M115.697698,J Biol Chem. 2016 Feb 16. pii: jbc.M115.697698,egil.lien@umassmed.edu,"The reduced virulence of the YopJ-YopM mutant is dependent on the presence of IL-1beta, IL-18 and caspase-1.",D Ratner 2016,2016,2 genes,Ratner-2016-Manipulation of IL-1beta and IL-18,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7972,PHI:6102,UniProt,Q8ZQ60,GenBank,AAL20019,,,LT2,PipA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,type III secretion system effector,,,NF-kappaB signaling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26933955,PubMed,10.1371/journal.ppat.1005484,PLoS Pathog. 2016 Mar 2;12(3):e1005484,jorge.galan@yale.edu,A SalmonellaTyphimurium strain lacking these effectors showed increased ability to stimulate NF-kappaB and increased virulence in an animal model of infection.,H Sun 2016,2016,3 genes,Sun-2016-A Family of Salmonella Type III Secre,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7973,PHI:6103,UniProt,A0A0D6GQ90,GenBank,ALE61592,,,33676,GogA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,type III secretion system effector,,,NF-kappaB signaling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26933955,PubMed,10.1371/journal.ppat.1005484,PLoS Pathog. 2016 Mar 2;12(3):e1005484,jorge.galan@yale.edu,A SalmonellaTyphimurium strain lacking these effectors showed increased ability to stimulate NF-kappaB and increased virulence in an animal model of infection.,H Sun 2016,2016,3 genes,Sun-2016-A Family of Salmonella Type III Secre,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7974,PHI:6104,UniProt,A0A0T9W9Z0,GenBank,CNR74913,,,CH43,GtgA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,type III secretion system effector,,,NF-kappaB signaling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26933955,PubMed,10.1371/journal.ppat.1005484,PLoS Pathog. 2016 Mar 2;12(3):e1005484,jorge.galan@yale.edu,A SalmonellaTyphimurium strain lacking these effectors showed increased ability to stimulate NF-kappaB and increased virulence in an animal model of infection.,H Sun 2016,2016,3 genes,Sun-2016-A Family of Salmonella Type III Secre,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7975,PHI:6105,UniProt,Q93NJ9,GenBank,AF372703_6,,,B301D,salA,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blue Lake 274,,,leaf,novel LuxR transcriptional regulators,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26954255,PubMed,10.1371/journal.pone.0150234,PLoS One. 2016 Mar 8;11(3):e0150234,d-gross@tamu.edu,"Deletion mutants of salA, syrF, andsyrGfailed to produce syringomycin and displayed reduction of virulence on bean",V L Vaughn 2016,2016,3 genes,"Vaughn-2016-Characterization of salA, syrF, an",BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7976,PHI:6106,UniProt,Q93NK4,GenBank,AF372703_1,,,B301D,syrF,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blue Lake 274,,,leaf,novel LuxR transcriptional regulators,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26954255,PubMed,10.1371/journal.pone.0150234,PLoS One. 2016 Mar 8;11(3):e0150234,d-gross@tamu.edu,"Deletion mutants of salA, syrF, andsyrGfailed to produce syringomycin and displayed reduction of virulence on bean",V L Vaughn 2016,2016,3 genes,"Vaughn-2016-Characterization of salA, syrF, an",BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7977,PHI:6107,UniProt,Q93NK0,GenBank,AF372703_5,,,B301D,syrG,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blue Lake 274,,,leaf,novel LuxR transcriptional regulators,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26954255,PubMed,10.1371/journal.pone.0150234,PLoS One. 2016 Mar 8;11(3):e0150234,d-gross@tamu.edu,"Deletion mutants of salA, syrF, andsyrGfailed to produce syringomycin and displayed reduction of virulence on bean",V L Vaughn 2016,2016,3 genes,"Vaughn-2016-Characterization of salA, syrF, an",BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7978,PHI:6106,UniProt,Q93NK4,GenBank,AF372703_1,,,B301D,syrF,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blue Lake 274,,,leaf,novel LuxR transcriptional regulators,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26954255,PubMed,10.1371/journal.pone.0150234,PLoS One. 2016 Mar 8;11(3):e0150234,d-gross@tamu.edu,"Deletion mutants of salA, syrF, andsyrGfailed to produce syringomycin and displayed reduction of virulence on bean",V L Vaughn 2016,2016,3 genes,"Vaughn-2016-Characterization of salA, syrF, an",BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7979,PHI:6107,UniProt,Q93NK0,GenBank,AF372703_5,,,B301D,syrG,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blue Lake 274,,,leaf,novel LuxR transcriptional regulators,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26954255,PubMed,10.1371/journal.pone.0150234,PLoS One. 2016 Mar 8;11(3):e0150234,d-gross@tamu.edu,"Deletion mutants of salA, syrF, andsyrGfailed to produce syringomycin and displayed reduction of virulence on bean",V L Vaughn 2016,2016,3 genes,"Vaughn-2016-Characterization of salA, syrF, an",BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7980,PHI:6108,UniProt,A0A0E1D1R8,GenBank,AHQ35794,,,EC20120916,GlmS,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain E2627,gastroenteritis; bacteremia; enteric fever,primates,9606,Homo sapiens (related: human),,,,intestinal epithelium,glutamine--fructose-6-phosphate aminotransferase,,,,reduced virulence,,,,,,,,,,no,SDS: CHEBI:8984; triton X-100: CHEBI:9750; novobiocin: CHEBI:28368; gentamicin; erythromycin; streptomycin,"SDS,   Triton   X-100,   novobiocin,  gentamicin: CHEBI:17833; erythromycin: CHEBI:48923; streptomycin: CHEBI:17076",,,,,gene deletion: full,,,RP,27017337,PubMed,10.1007/s00203-016-1212-x,Arch Microbiol. 2016 Mar 26,fadl@wisc.edu,"deltaglmS was highly sensitive to detergents, hydrophobic antibiotics, and bile salts compared to the wild type (WT).",A M Bennett 2016,2016,1 gene,Bennett-2016-Functional characterization of gl,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7981,PHI:6109,UniProt,A0A0K0GKS2,GenBank,ACD58842,,,PXO99A,GdpX1,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,GdpX1 inhibits virulence in rice and T3SS-related gene transcription,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption,,,RP,26929398,PubMed,10.1111/jam.13115,J Appl Microbiol. 2016 Feb 29,hechenyang@caas.cn,"GdpX1 is the first GGDEF-domain protein functionally characterized in Xoo, which functions as a negative regulator of bacterial virulence via suppression of virulence-related gene transcription.",F Yang 2016,2016,1 gene,Yang-2016-The GGDEF-domain protein GdpX1 atten,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7982,PHI:6109,UniProt,A0A0K0GKS2,GenBank,ACD58842,,,PXO99A,GdpX1,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica,,,leaf,GdpX1 inhibits virulence in rice and T3SS-related gene transcription,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26929398,PubMed,10.1111/jam.13115,J Appl Microbiol. 2016 Feb 29,hechenyang@caas.cn,"GdpX1 is the first GGDEF-domain protein functionally characterized in Xoo, which functions as a negative regulator of bacterial virulence via suppression of virulence-related gene transcription.",F Yang 2016,2016,1 gene,Yang-2016-The GGDEF-domain protein GdpX1 atten,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7983,PHI:6110,UniProt,D0ZV90,GenBank,ACY87895,,,14028S,PhoP,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,part of the two-component system PhoP-PhoQ that regulates virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26943369,PubMed,10.1371/journal.ppat.1005458,PLoS Pathog. 2016 Mar 4;12(3):e1005458,yfyao@sjtu.edu.cn,"Acetylation of K201 (mimicked by glutamine substitute) in S. Typhimurium causes significantly attenuated intestinal inflammation as well as systemic infection in mouse model, suggesting that deacetylation of PhoP K201 is essential for Salmonella pathogenesis.",J Ren 2016,2016,1 gene,Ren-2016-Acetylation of Lysine 201 Inhibits th,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7984,PHI:6111,UniProt,Q4WQK8,GenBank,EAL89476,,,Af293,CpcB,,,,,,,746128,Aspergillus fumigatus,,A1160C,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,involved in antifungal drug susceptibility and virulence,,,,reduced virulence,,,,,,reduced,,reduced,,no,voriconazole; bifonazole; terbinafine; amphotericin B,"voriconazole: CHEBI:10023; bifonazole: CHEBI:31286; terbinafine: CHEBI:9448, CAS:91161-71-6; amphotericin B: CHEBI:2682",,,,,gene mutation,,,RP,26903985,PubMed,10.3389/fmicb.2016.00106,Front Microbiol. 2016 Feb 9;7:106,linglu@njnu.edu.cn,W-D residue in WD repeat 2 of CpcB are required not only to control normal hyphal growth and conidiation but also to affect antifungal drug susceptibility.,Z Cai 2016,2016,1 gene,Cai-2016-Molecular Characterization of Gbeta-L,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7985,PHI:6112,UniProt,Q2FXF2,GenBank,AF422190_2,,,ATCC 35556,sigS,,,,,,,1280,Staphylococcus aureus,948561,serotype O11,mastitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,mammary gland,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27016756,PubMed,10.1016/j.vetmic.2016.02.014,Vet Microbiol. 2016 Apr 15;186:44-51,yves.leloir@rennes.inra.fr,"While no significant differences in the effect on bacterial growth between O11 and O11DsigS were observed either in vitro or in vivo, a significantly weaker in vivo production of interleukin (IL)-1a, IL-1b, and Tumor Necrosis Factor (TNF)-a was measured in the mammary glands infected with the mutant strain, suggesting that infection with O11DsigS induced an attenuated local innate immune response.",V Peton 2016,2016,1 gene,Peton-2016-Disruption of the sigS gene attenua,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7986,PHI:6113,,no data found,,,,,,RovM,,,,,,,632,Yersinia pestis,,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,LysR-type transcription factor,,,,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,RP,26984293,PubMed,10.1098/rsob.150198,Open Biol. 2016 Mar;6(3). pii: 150198,ruifuyang@gmail.com,"RovM and RovA appear to enhance and inhibit biofilm formation, respectively, while also inhibiting and enhancing virulence, respectively.",L Liu 2016,2016,2 genes,Liu-2016-Reciprocal regulation of Yersinia pes,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7987,PHI:6114,UniProt,P69988,GenBank,AAM85527,,,KIM10+,RovA,,,,,,,632,Yersinia pestis,,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,MarR-family regulator,,,,reduced virulence,,,,,,,,increased; aberrant,,no,,,,,,,gene deletion: full,,,RP,26984293,PubMed,10.1098/rsob.150198,Open Biol. 2016 Mar;6(3). pii: 150198,ruifuyang@gmail.com,"RovM and RovA appear to enhance and inhibit biofilm formation, respectively, while also inhibiting and enhancing virulence, respectively.",L Liu 2016,2016,2 genes,Liu-2016-Reciprocal regulation of Yersinia pes,BATCH_058,2016-04-01,MC,,,,,,,,,,,,,
,,Record 7988,PHI:4258,UniProt,G3C9R4,GenBank,CCC55840; Ensembl: HpaG814111,,,Emoy2,HaRxL106,,YFPn-HaRxL106,,,,,272952,Hyaloperonospora arabidopsidis,559515,,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: nicotiana benthamiana),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,MOS6-YFPc,UniProt: O04294; Ensembl: AT4G02150,positive BiFC (speckles at nuclear rim),,functional test in host: transient expression,"coinfiltration in Nb, confocal microscopy performed 48h after infiltration",,AC,25284001,PubMed,10.1111/tpj.12691,Plant J.2015 Jan;81(1):40-52,mark.banfield@jic.ac.uk,"Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943 showed HaRxL106 interacts with MOS6/importin -alpha3, importin-alpha1, -alpha2 and -alpha4. Arabidopsis mos6 mutants are more susceptible to compatible Hpa races (Palma et al., 2005 PMID: 15964279) and weakly virulent strains of P. syringae (this study). This study also demonstrates direct interaction between HaRxL106 and MOS6 in vitro using expressed and purified proteins from E.coli in size exclusion chromatography (SEC), and a low micro-molar binding affinity from isothermal titration calorimetry (ITC) as expected for a canonical cargo/ importin-alpha interaction. Serial N-terminal deletion constructs of HaRxL106 demonstrated a C-terminal 58 amino acid region with predicted NLS was required for nuclear localisation and binding to MOS6 (in co-IP, this study).",Wirthmueller 2015,2015,,,AC First host target curation,2016-05-26,RRes,,,,,,,,,,,,,
,,Record 7989,PHI:4258,UniProt,G3C9R4,GenBank,CCC55840; Ensembl: HpaG814111,,,Emoy2,HaRxL106,,YFPn-HaRxL106deltaC (deletion of C-terminal 58 amino acids required for nuclear localisation (NLS) and binding to MOS6 (co-IP assay),,,,,272952,Hyaloperonospora arabidopsidis,559515,,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: nicotiana benthamiana),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,MOS6-YFPc,UniProt: O04294; Ensembl: AT4G02150,negative BiFC (no speckles),,functional test in host: transient expression,"coinfiltration in Nb, confocal microscopy performed 48h after infiltration",,AC,25284001,PubMed,10.1111/tpj.12691,Plant J.2015 Jan;81(1):40-52,mark.banfield@jic.ac.uk,"Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943 showed HaRxL106 interacts with MOS6/importin -alpha3, importin-alpha1, -alpha2 and -alpha4. Arabidopsis mos6 mutants are more susceptible to compatible Hpa races (Palma et al., 2005 PMID: 15964279) and weakly virulent strains of P. syringae (this study). This study also demonstrates direct interaction between HaRxL106 and MOS6 in vitro using expressed and purified proteins from E.coli in size exclusion chromatography (SEC), and a low micro-molar binding affinity from isothermal titration calorimetry (ITC) as expected for a canonical cargo/ importin-alpha interaction. Serial N-terminal deletion constructs of HaRxL106 demonstrated a C-terminal 58 amino acid region with predicted NLS was required for nuclear localisation and binding to MOS6 (in co-IP, this study).",Wirthmueller 2015,2015,,,AC First host target curation,2016-05-26,RRes,,,,,,,,,,,,,
,,Record 7990,PHI:4258,UniProt,G3C9R4,GenBank,CCC55840; Ensembl: HpaG814111,,,Emoy2,HaRxL106,,HS-HaRxL106,,,,,272952,Hyaloperonospora arabidopsidis,559515,,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: nicotiana benthamiana),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,MOS6-GFP,UniProt: O04294; Ensembl: AT4G02150,positive co-IP,,functional test in host: transient expression,"coinfiltration in Nb, 48h MOS-GFP IP-ed and co-purifying HS-tagged proteins detected by anti-HA Western blot",,AC,25284001,PubMed,10.1111/tpj.12691,Plant J.2015 Jan;81(1):40-52,mark.banfield@jic.ac.uk,"Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943 showed HaRxL106 interacts with MOS6/importin -alpha3, importin-alpha1, -alpha2 and -alpha4. Arabidopsis mos6 mutants are more susceptible to compatible Hpa races (Palma et al., 2005 PMID: 15964279) and weakly virulent strains of P. syringae (this study). This study also demonstrates direct interaction between HaRxL106 and MOS6 in vitro using expressed and purified proteins from E.coli in size exclusion chromatography (SEC), and a low micro-molar binding affinity from isothermal titration calorimetry (ITC) as expected for a canonical cargo/ importin-alpha interaction. Serial N-terminal deletion constructs of HaRxL106 demonstrated a C-terminal 58 amino acid region with predicted NLS was required for nuclear localisation and binding to MOS6 (in co-IP, this study).",Wirthmueller 2015,2015,,,AC First host target curation,2016-05-26,RRes,,,,,,,,,,,,,
,,Record 7991,PHI:4258,UniProt,G3C9R4,GenBank,CCC55840; Ensembl: HpaG814111,,,Emoy2,HaRxL106,,HS-HaRxL106deltaC (deletion of C-terminal 58 amino acids required for nuclear localisation (NLS) and binding to MOS6 (co-IP assay),,,,,272952,Hyaloperonospora arabidopsidis,559515,,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: nicotiana benthamiana),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,MOS6-GFP,UniProt: O04294; Ensembl: AT4G02150,negative co-IP,,functional test in host: transient expression,"coinfiltration in Nb, 48h MOS-GFP IP-ed and co-purifying HS-tagged proteins detected by anti-HA Western blot",,AC,25284001,PubMed,10.1111/tpj.12691,Plant J.2015 Jan;81(1):40-52,mark.banfield@jic.ac.uk,"Interactome data from large Y2H screen of 83 (Hpa and Pst) effectors and 8000 Arabidopsis proteins by Mukhtar et al., 2011 Science. PMID: 21798943 showed HaRxL106 interacts with MOS6/importin -alpha3, importin-alpha1, -alpha2 and -alpha4. Arabidopsis mos6 mutants are more susceptible to compatible Hpa races (Palma et al., 2005 PMID: 15964279) and weakly virulent strains of P. syringae (this study). This study also demonstrates direct interaction between HaRxL106 and MOS6 in vitro using expressed and purified proteins from E.coli in size exclusion chromatography (SEC), and a low micro-molar binding affinity from isothermal titration calorimetry (ITC) as expected for a canonical cargo/ importin-alpha interaction. Serial N-terminal deletion constructs of HaRxL106 demonstrated a C-terminal 58 amino acid region with predicted NLS was required for nuclear localisation and binding to MOS6 (in co-IP, this study).",Wirthmueller 2015,2015,,,AC First host target curation,2016-05-26,RRes,,,,,,,,,,,,,
,,Record 7992,PHI:3534,UniProt,B8NHY6,GenBank,EED51157,,,NRRL3357,DmtA,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,cotyledon,methyltransferase,,,,reduced virulence,,,,,,increased; aberrant,,aberrant,,no,sorbitol; KCl; NaCl; Congo red; calcofluor white,KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653,,,,,gene deletion: full,,,RP,26979781,PubMed,10.1038/srep23259,Sci Rep. 2016 Mar 16;6:23259,wshyyl@sina.com,"DmtA, apart from being a C-5 cytosine methyltransferase in A. flavus, contributes to asexual development, aflatoxin biosynthesis, sclerotial production and virulence.",K Yang 2016,2016,1 gene,Yang-2016-The DmtA methyltransferase contribut,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 7993,PHI:6115,UniProt,A0A0K0GQL3,GenBank,ACD61140,,,PXO99A,stoS,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,sensor histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26957113,PubMed,10.1038/srep22768,Sci Rep. 2016 Mar 9;6:22768,ruanlifang@mail.hzau.edu.cn,Xoo equipped with StoS and SreKRS outcompetes strains without StoS or SreKRS in co-infected rice and grows outside the host.,D Zheng 2016,2016,4 genes,Zheng-2016-Two overlapping two-component syste,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 7994,PHI:6116,UniProt,A0A0K0GH83,GenBank,ACD57581,,,PXO99A,sreK,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,two-component system regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26957113,PubMed,10.1038/srep22768,Sci Rep. 2016 Mar 9;6:22768,ruanlifang@mail.hzau.edu.cn,Xoo equipped with StoS and SreKRS outcompetes strains without StoS or SreKRS in co-infected rice and grows outside the host.,D Zheng 2016,2016,4 genes,Zheng-2016-Two overlapping two-component syste,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 7995,PHI:6117,UniProt,A0A0K0GHK1,GenBank,ACD57582,,,PXO99A,sreR,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,two-component system regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26957113,PubMed,10.1038/srep22768,Sci Rep. 2016 Mar 9;6:22768,ruanlifang@mail.hzau.edu.cn,Xoo equipped with StoS and SreKRS outcompetes strains without StoS or SreKRS in co-infected rice and grows outside the host.,D Zheng 2016,2016,4 genes,Zheng-2016-Two overlapping two-component syste,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 7996,PHI:6118,UniProt,A0A0K0GHD4,GenBank,ACD57583,,,PXO99A,sreS,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,histidine kinase-response regulator hybrid protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26957113,PubMed,10.1038/srep22768,Sci Rep. 2016 Mar 9;6:22768,ruanlifang@mail.hzau.edu.cn,Xoo equipped with StoS and SreKRS outcompetes strains without StoS or SreKRS in co-infected rice and grows outside the host.,D Zheng 2016,2016,4 genes,Zheng-2016-Two overlapping two-component syste,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 7997,PHI:6119,UniProt,A0A0E0S977,EMBL,FGRAMPH1_01T22563,,,PH-1,BTA1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. B73,,,stem,betaine lipid synthase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26974960,PubMed,10.1371/journal.ppat.1005485,PLoS Pathog. 2016 Mar 14;12(3):e1005485,whtang@sibs.ac.cn,,Y Zhang 2016,2016,9 genes,Zhang-2016-Cellular Tracking and Gene Profilin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 7998,PHI:6120,UniProt,I1RJ45,GenBank,ESU09337,,,PH-1,FGSG_03846,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. B73,,,stem,TAG lipases,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26974960,PubMed,10.1371/journal.ppat.1005485,PLoS Pathog. 2016 Mar 14;12(3):e1005485,whtang@sibs.ac.cn,,Y Zhang 2016,2016,9 genes,Zhang-2016-Cellular Tracking and Gene Profilin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 7999,PHI:6121,UniProt,I1RHI8,GenBank,ESU10009,,,PH-1,FGSG_03243,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. B73,,,stem,TAG lipases,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26974960,PubMed,10.1371/journal.ppat.1005485,PLoS Pathog. 2016 Mar 14;12(3):e1005485,whtang@sibs.ac.cn,,Y Zhang 2016,2016,9 genes,Zhang-2016-Cellular Tracking and Gene Profilin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8000,PHI:6122,UniProt,I1RR94,GenBank,ESU12721,,,PH-1,FGSG_06610,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. B73,,,stem,,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26974960,PubMed,10.1371/journal.ppat.1005485,PLoS Pathog. 2016 Mar 14;12(3):e1005485,whtang@sibs.ac.cn,,Y Zhang 2016,2016,9 genes,Zhang-2016-Cellular Tracking and Gene Profilin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8001,PHI:6123,UniProt,I1RHV1,GenBank,ESU09866,,,PH-1,FGSG_03366,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. B73,,,stem,,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26974960,PubMed,10.1371/journal.ppat.1005485,PLoS Pathog. 2016 Mar 14;12(3):e1005485,whtang@sibs.ac.cn,,Y Zhang 2016,2016,9 genes,Zhang-2016-Cellular Tracking and Gene Profilin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8002,PHI:6124,UniProt,I1RU06,GenBank,ESU13966,,,PH-1,FGSG_07678,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. B73,,,stem,,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26974960,PubMed,10.1371/journal.ppat.1005485,PLoS Pathog. 2016 Mar 14;12(3):e1005485,whtang@sibs.ac.cn,,Y Zhang 2016,2016,9 genes,Zhang-2016-Cellular Tracking and Gene Profilin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8003,PHI:6125,UniProt,I1RHY5,GenBank,ESU09824,,,PH-1,FGSG_03402,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. B73,,,stem,putative phosphatase genes,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26974960,PubMed,10.1371/journal.ppat.1005485,PLoS Pathog. 2016 Mar 14;12(3):e1005485,whtang@sibs.ac.cn,,Y Zhang 2016,2016,9 genes,Zhang-2016-Cellular Tracking and Gene Profilin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8004,PHI:6126,UniProt,I1RU98,GenBank,ESU14094,,,PH-1,FGSG_07783,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. B73,,,stem,putative phosphatase genes,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26974960,PubMed,10.1371/journal.ppat.1005485,PLoS Pathog. 2016 Mar 14;12(3):e1005485,whtang@sibs.ac.cn,,Y Zhang 2016,2016,9 genes,Zhang-2016-Cellular Tracking and Gene Profilin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8005,PHI:6127,UniProt,I1S368,GenBank,ESU17477,,,PH-1,PLC,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. B73,,,stem,phospholipase C,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26974960,PubMed,10.1371/journal.ppat.1005485,PLoS Pathog. 2016 Mar 14;12(3):e1005485,whtang@sibs.ac.cn,,Y Zhang 2016,2016,9 genes,Zhang-2016-Cellular Tracking and Gene Profilin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8006,PHI:6128,UniProt,K9FV70,GenBank,EKV12387,,,Pd1,ku70,,,,,,,36651,Penicillium digitatum,1170229,isolate PHI26 strain CECT20796,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,forms a heterodimer that binds DNA ends and is also involved in telomere maintenance,,,non-homologous end-joining pathway (NHEJ) pathway,unaffected pathogenicity,,,,,,,wild type,wild type,,no,,,,,,,gene mutation,,,RP,26895860,PubMed,10.1016/j.funbio.2015.11.001,Fungal Biol. 2016 Mar;120(3):317-23,jmarcos@iata.csic.es,"P. digitatum Dku70 strains showed no differences from the parental strain in vegetative growth, asexual development or virulence to citrus fruit, when experiments were conducted at the optimal temperature of24C. However, growth of Dku70 strains at temperatures higher than 24C demonstrated a detrimental effect in axenic growth and conidia production.",M Gandia 2016,2016,1 gene,Gandia-2016-Disruption of ku70 involved in non,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8007,PHI:6129,UniProt,Q8IIU7,GenBank,CZT98722,,,3D7,PTEX88,,,,,,,5833,Plasmodium falciparum,36329,3D7,malaria,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,adipose tissue; lung; spleen,Plasmodium translocon of exported proteins component,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: downregulation,,,RP,26886275,PubMed,10.1371/journal.pone.0149296,PLoS One. 2016 Feb 17;11(2):e0149296,taniad@deakin.edu.au,PTEX88-deficient P.berghei were incapable of causing cerebral malaria despite a robust pro-inflammatory response from the host.,S A Chisholm 2016,2016,2 genes,Chisholm-2016-Contrasting Inducible Knockdown,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8008,PHI:6130,UniProt,A0A077XE85,GenBank,CDS46892,,,ANKA,PTEX88,,,,,,,5821,Plasmodium berghei,5823,ANKA,malaria,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,adipose tissue; lung; spleen,Plasmodium translocon of exported proteins component,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: downregulation,,,RP,26886275,PubMed,10.1371/journal.pone.0149296,PLoS One. 2016 Feb 17;11(2):e0149296,taniad@deakin.edu.au,PTEX88-deficient P.berghei were incapable of causing cerebral malaria despite a robust pro-inflammatory response from the host.,S A Chisholm 2016,2016,2 genes,Chisholm-2016-Contrasting Inducible Knockdown,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8009,PHI:6131,UniProt,Q8E6Y0,GenBank,CAD46072,,,NEM316,PbsP,,,,,,,1311,Streptococcus agalactiae,211110,NEM316,group B streptococcal infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; kidney; brain,plasminogen binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26888569,PubMed,10.1111/mmi.13357,Mol Microbiol. 2016 Feb 16,gteti@unime.it,absence of PbsP results in a decreased bacterial transmigration across brain endothelial cells and impaired virulence in a murine model of infection.,M Buscetta 2016,2016,1 gene,"Buscetta-2016-PbsP, a cell wall-anchored prote",BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8010,PHI:6133,UniProt,Q6PT92,GenBank,AAT01052,,,,blaCMY-2,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26862033,PubMed,10.1186/s12866-016-0633-7,BMC Microbiol. 2016 Feb 9;16:18,csilvamex1@yahoo.com,"blaCMY-2 was carried on the conjugative IncF plasmid, instead of the IncA/C plasmid, as found in previously studied ST213 strains and this Strain 33676 was fully attenuated for virulence in BALB/c mice infections.",M Wiesner 2016,2016,1 gene,Wiesner-2016-A multi-drug resistant Salmonella,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8011,PHI:6134,UniProt,I1RC73,GenBank,ESU06462,,,PH-1,FHS1,,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,DNA damage response,,,,reduced virulence,yes,,,,,,reduced,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,26888604,PubMed,10.1038/srep21572,Sci Rep. 2016 Feb 18;6:21572,lee2443@snu.ac.kr,"Fhs1 is a fungal specific Zn(II)2Cys6 TF that localises exclusively to nuclei. fhs1deletion mutants were hypersensitive to hydroxyurea and defective in mitotic cell division. Moreover, deletion of FHS1 resulted in defects in perithecia production and virulence and led to the accumulation of DNA damage.",H Son 2016,2016,1 gene,Son-2016-A novel transcription factor gene FHS,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8012,PHI:6135,UniProt,A4RJV3,GenBank,EHA54899,,,70-15,PEF1,chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,mitochondrial division protein,,,,reduced virulence,,no,yes,yes,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26950649,PubMed,10.1111/mpp.12395,Mol Plant Pathol. 2016 Mar 7,chenxiaolin@mail.hzau.edu.cn,Targeted deletion of PEF1resulted in reduction of virulence and retardationof penetration and invasive growth in host cells.,X CHEN 2016,2016,1 gene,Chen-2016-Peroxisomal fission is induced durin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8013,PHI:6135,UniProt,A4RJV3,GenBank,EHA54899,,,70-15,PEF1,chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,mitochondrial division protein,,,,reduced virulence,,no,yes,yes,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26950649,PubMed,10.1111/mpp.12395,Mol Plant Pathol. 2016 Mar 7,chenxiaolin@mail.hzau.edu.cn,Targeted deletion of PEF1resulted in reduction of virulence and retardationof penetration and invasive growth in host cells.,X CHEN 2016,2016,1 gene,Chen-2016-Peroxisomal fission is induced durin,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8014,PHI:6136,UniProt,Q71ZM6,GenBank,AAT04238,,,F2365,PrsA1,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,spleen; liver,foldase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27007641,PubMed,10.1111/mmi.13367,Mol Microbiol. 2016 Mar 23,nfreitag@uic.edu,"PrsA1 and PrsA2 are secreted bacterial lipoprotein chaperones that contribute to the folding of proteins translocated across the bacterial membrane; PrsA2 is required for L. monocytogenes virulence, PrsA1 in bacterial resistance to alcohol.",L A Cahoon 2016,2016,2 genes,Cahoon-2016-A structural comparison of Listeri,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8015,PHI:6137,UniProt,Q71XE6,GenBank,AAT05019,,,F2365,PrsA2,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,spleen; liver,foldase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27007641,PubMed,10.1111/mmi.13367,Mol Microbiol. 2016 Mar 23,nfreitag@uic.edu,"PrsA1 and PrsA2 are secreted bacterial lipoprotein chaperones that contribute to the folding of proteins translocated across the bacterial membrane; PrsA2 is required for L. monocytogenes virulence, PrsA1 in bacterial resistance to alcohol.",L A Cahoon 2016,2016,2 genes,Cahoon-2016-A structural comparison of Listeri,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8016,PHI:6138,UniProt,A4VTU5,GenBank,ABP89534,,,05ZYH33,cps2E,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; heart; kidney; spleen,glycosyltransferases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26946377,PubMed,10.1016/j.micres.2016.02.002,Microbiol Res. 2016 Apr;185:45-54,tanchen@mail.hzau.edu.cn,"In a mouse model of infection, the mutant strains were rapidly cleared by the immune system, compared with the wild-type strain.",Y Zhang 2016,2016,4 Genes,Zhang-2016-Effect of the glycosyltransferases,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8017,PHI:6139,UniProt,Q9X4V1,GenBank,AF118389_10,,,10,cps2G,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; heart; kidney; spleen,glycosyltransferases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26946377,PubMed,10.1016/j.micres.2016.02.002,Microbiol Res. 2016 Apr;185:45-54,tanchen@mail.hzau.edu.cn,"In a mouse model of infection, the mutant strains were rapidly cleared by the immune system, compared with the wild-type strain.",Y Zhang 2016,2016,4 Genes,Zhang-2016-Effect of the glycosyltransferases,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8018,PHI:6140,UniProt,A4VTV0,GenBank,ABP89539,,,05ZYH33,cps2J,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; heart; kidney; spleen,glycosyltransferases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26946377,PubMed,10.1016/j.micres.2016.02.002,Microbiol Res. 2016 Apr;185:45-54,tanchen@mail.hzau.edu.cn,"In a mouse model of infection, the mutant strains were rapidly cleared by the immune system, compared with the wild-type strain.",Y Zhang 2016,2016,4 Genes,Zhang-2016-Effect of the glycosyltransferases,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8019,PHI:6141,UniProt,Q2MZ74,GenBank,ABB71975,,,,cps2L,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; heart; kidney; spleen,glycosyltransferases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26946377,PubMed,10.1016/j.micres.2016.02.002,Microbiol Res. 2016 Apr;185:45-54,tanchen@mail.hzau.edu.cn,"In a mouse model of infection, the mutant strains were rapidly cleared by the immune system, compared with the wild-type strain.",Y Zhang 2016,2016,4 Genes,Zhang-2016-Effect of the glycosyltransferases,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8020,PHI:6142,UniProt,B1PWB6,GenBank,ACA53384,,,F6214,glcV,,,,,,,1639,Listeria monocytogenes,,F6214-1,listeriosis,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen; liver,resistance to a wall teichoic acid (WTA)-binding bacteriophage,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26871418,PubMed,10.1111/mmi.13353,Mol Microbiol. 2016 Feb 12,paul_orndorff@ncsu.edu,All mutants were profoundly attenuated in orally infected mice and were impaired in cell-to-cell spread in vitro.,P A Spears 2016,2016,4 genes,Spears-2016-Listeria monocytogenes Wall Teicho,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8021,PHI:6143,,no data found,,,,,,pmpA,,,,,,,1639,Listeria monocytogenes,,F6214-1,listeriosis,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen; liver,resistance to a wall teichoic acid (WTA)-binding bacteriophage,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26871418,PubMed,10.1111/mmi.13353,Mol Microbiol. 2016 Feb 12,paul_orndorff@ncsu.edu,All mutants were profoundly attenuated in orally infected mice and were impaired in cell-to-cell spread in vitro.,P A Spears 2016,2016,4 genes,Spears-2016-Listeria monocytogenes Wall Teicho,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8022,PHI:6144,UniProt,A0A0E0UVG9,GenBank,AEH92113,,,M7,galU,,,,,,,1639,Listeria monocytogenes,,F6214-1,listeriosis,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen; liver,resistance to a wall teichoic acid (WTA)-binding bacteriophage,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26871418,PubMed,10.1111/mmi.13353,Mol Microbiol. 2016 Feb 12,paul_orndorff@ncsu.edu,All mutants were profoundly attenuated in orally infected mice and were impaired in cell-to-cell spread in vitro.,P A Spears 2016,2016,4 genes,Spears-2016-Listeria monocytogenes Wall Teicho,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8023,PHI:6145,UniProt,Q9ZH29,GenBank,AAD09998,,,4b1,gtcA,,,,,,,1639,Listeria monocytogenes,,F6214-1,listeriosis,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen; liver,resistance to a wall teichoic acid (WTA)-binding bacteriophage,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26871418,PubMed,10.1111/mmi.13353,Mol Microbiol. 2016 Feb 12,paul_orndorff@ncsu.edu,All mutants were profoundly attenuated in orally infected mice and were impaired in cell-to-cell spread in vitro.,P A Spears 2016,2016,4 genes,Spears-2016-Listeria monocytogenes Wall Teicho,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8024,PHI:6146,UniProt,Q4WPM7,GenBank,EAL89807,,,Af293,HorA,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,hypoxia-induced oxidoreductase,,,,reduced virulence,,,,,,,,reduced,reduced,no,H2O2; menadione; voriconazole; terbinafine,"H2O2: CHEBI:16240; menadione: CHEBI:28869; ,voriconazole: CHEBI:10023; terbinafine: CHEBI:9448, CAS:91161-71-6",,,,,gene disruption; gene complementation,,,RP,26991818,PubMed,10.1111/mmi.13377,Mol Microbiol. 2016 Mar 17,olaf.kniemeyer@leibniz-hki.de,"The strain deltahorA displayed an impaired response to both oxidative and reductive stress, a delay in germination and an accumulation of NADH.",K Kroll 2016,2016,1 gene,Kroll-2016-The hypoxia-induced dehydrogenase H,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8025,PHI:6147,UniProt,G2X869,GenBank,EGY15156,,,VdLs.17,VdNRS/ER,,,,,,,27337,Verticillium dahliae,,Vd8,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf; root,nucleotide-rhamnose synthase/epimerase-reductase,,,,loss of pathogenicity,,,,,,wild type,,wild type,,no,mannitol; sodium chloride; sorbitol; congo red,mannitol: CHEBI:29864; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,26996832,PubMed,10.1111/mpp.12401,Mol Plant Pathol. 2016 Mar 21,bart.thomma@wur.nl,VdNRS/ER is not involved in cell wall integrity or osmotic stress resistance during mycelium development.,P Santhanam 2016,2016,1 gene,Santhanam-2016-Rhamnose synthase activity is r,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8026,PHI:6148,UniProt,I1RKR8,GenBank,ESU08612,,,PH-1,FgSsn3,chromosome 2,,,Ssn8; Srb8; Srb9,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,meiotic mRNA stability protein kinase,,,,reduced virulence,yes,,,yes,,aberrant,,reduced,aberrant,no,,,,,,,gene mutation; gene complementation,,,RP,26931632,PubMed,10.1038/srep22333,Sci Rep. 2016 Mar 2;6:22333,jqiaojun@nwsuaf.edu.cn,"Ssn3 interacts with Ssn8 (a C-type cyclin), Srb8 (Med12), and Srb9 (Med13) to form the kinase module of the mediator complex.",S Cao 2016,2016,1 gene,"Cao-2016-FgSsn3 kinase, a component of the med",BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8027,PHI:6149,,no data found,,,,,,msfA1,,,,,,,727,Haemophilus influenzae,374933,PittII,otitis media; invasive disease,rodents,10152,Chinchilla chinchilla (related: short-tailed chinchilla),,,,brain,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26977929,PubMed,10.1371/journal.pone.0149891,PLoS One. 2016 Mar 15;11(3):e0149891,bjanto@drexelmed.edu,"Deleting all four of these genes (msfA1-4) (KO) resulted in a highly significant decrease in phagocytosis and survival in macrophages; which was fully complemented by a single copy of the msfA1 gene. Using the chinchilla model of otitis media and invasive disease, the KO strain displayed a significant decrease in fitness compared to the WT in coinfections; and in single infections, the KO lost its ability to invade the brain.",J M Kress-Bennett 2016,2016,4 genes,Kress-Bennett-2016-Identification and Characte,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8028,PHI:6150,,no data found,,,,,,msfA2,,,,,,,727,Haemophilus influenzae,374933,PittII,otitis media; invasive disease,rodents,10152,Chinchilla chinchilla (related: short-tailed chinchilla),,,,brain,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26977929,PubMed,10.1371/journal.pone.0149891,PLoS One. 2016 Mar 15;11(3):e0149891,bjanto@drexelmed.edu,"Deleting all four of these genes (msfA1-4) (KO) resulted in a highly significant decrease in phagocytosis and survival in macrophages; which was fully complemented by a single copy of the msfA1 gene. Using the chinchilla model of otitis media and invasive disease, the KO strain displayed a significant decrease in fitness compared to the WT in coinfections; and in single infections, the KO lost its ability to invade the brain.",J M Kress-Bennett 2016,2016,4 genes,Kress-Bennett-2016-Identification and Characte,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8029,PHI:6151,,no data found,,,,,,msfA3,,,,,,,727,Haemophilus influenzae,374933,PittII,otitis media; invasive disease,rodents,10152,Chinchilla chinchilla (related: short-tailed chinchilla),,,,brain,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26977929,PubMed,10.1371/journal.pone.0149891,PLoS One. 2016 Mar 15;11(3):e0149891,bjanto@drexelmed.edu,"Deleting all four of these genes (msfA1-4) (KO) resulted in a highly significant decrease in phagocytosis and survival in macrophages; which was fully complemented by a single copy of the msfA1 gene. Using the chinchilla model of otitis media and invasive disease, the KO strain displayed a significant decrease in fitness compared to the WT in coinfections; and in single infections, the KO lost its ability to invade the brain.",J M Kress-Bennett 2016,2016,4 genes,Kress-Bennett-2016-Identification and Characte,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8030,PHI:6152,,no data found,,,,,,msfA4,,,,,,,727,Haemophilus influenzae,374933,PittII,otitis media; invasive disease,rodents,10152,Chinchilla chinchilla (related: short-tailed chinchilla),,,,brain,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26977929,PubMed,10.1371/journal.pone.0149891,PLoS One. 2016 Mar 15;11(3):e0149891,bjanto@drexelmed.edu,"Deleting all four of these genes (msfA1-4) (KO) resulted in a highly significant decrease in phagocytosis and survival in macrophages; which was fully complemented by a single copy of the msfA1 gene. Using the chinchilla model of otitis media and invasive disease, the KO strain displayed a significant decrease in fitness compared to the WT in coinfections; and in single infections, the KO lost its ability to invade the brain.",J M Kress-Bennett 2016,2016,4 genes,Kress-Bennett-2016-Identification and Characte,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8031,PHI:6149,,no data found,,,,,,msfA1,,,,,,PHI:6150; PHI:6151; PHI:6152,727,Haemophilus influenzae,374933,PittII,otitis media; invasive disease,rodents,10152,Chinchilla chinchilla (related: short-tailed chinchilla),,,,brain,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26977929,PubMed,10.1371/journal.pone.0149891,PLoS One. 2016 Mar 15;11(3):e0149891,bjanto@drexelmed.edu,"Deleting all four of these genes (msfA1-4) (KO) resulted in a highly significant decrease in phagocytosis and survival in macrophages; which was fully complemented by a single copy of the msfA1 gene. Using the chinchilla model of otitis media and invasive disease, the KO strain displayed a significant decrease in fitness compared to the WT in coinfections; and in single infections, the KO lost its ability to invade the brain.",J M Kress-Bennett 2016,2016,4 genes,Kress-Bennett-2016-Identification and Characte,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8032,PHI:6150,,no data found,,,,,,msfA2,,,,,,PHI:6149; PHI:6151; PHI:6152,727,Haemophilus influenzae,374933,PittII,otitis media; invasive disease,rodents,10152,Chinchilla chinchilla (related: short-tailed chinchilla),,,,brain,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26977929,PubMed,10.1371/journal.pone.0149891,PLoS One. 2016 Mar 15;11(3):e0149891,bjanto@drexelmed.edu,"Deleting all four of these genes (msfA1-4) (KO) resulted in a highly significant decrease in phagocytosis and survival in macrophages; which was fully complemented by a single copy of the msfA1 gene. Using the chinchilla model of otitis media and invasive disease, the KO strain displayed a significant decrease in fitness compared to the WT in coinfections; and in single infections, the KO lost its ability to invade the brain.",J M Kress-Bennett 2016,2016,4 genes,Kress-Bennett-2016-Identification and Characte,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8033,PHI:6151,,no data found,,,,,,msfA3,,,,,,PHI:6149; PHI:6150; PHI:6152,727,Haemophilus influenzae,374933,PittII,otitis media; invasive disease,rodents,10152,Chinchilla chinchilla (related: short-tailed chinchilla),,,,brain,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26977929,PubMed,10.1371/journal.pone.0149891,PLoS One. 2016 Mar 15;11(3):e0149891,bjanto@drexelmed.edu,"Deleting all four of these genes (msfA1-4) (KO) resulted in a highly significant decrease in phagocytosis and survival in macrophages; which was fully complemented by a single copy of the msfA1 gene. Using the chinchilla model of otitis media and invasive disease, the KO strain displayed a significant decrease in fitness compared to the WT in coinfections; and in single infections, the KO lost its ability to invade the brain.",J M Kress-Bennett 2016,2016,4 genes,Kress-Bennett-2016-Identification and Characte,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8034,PHI:6152,,no data found,,,,,,msfA4,,,,,,PHI:6149; PHI:6150; PHI:6151,727,Haemophilus influenzae,374933,PittII,otitis media; invasive disease,rodents,10152,Chinchilla chinchilla (related: short-tailed chinchilla),,,,brain,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26977929,PubMed,10.1371/journal.pone.0149891,PLoS One. 2016 Mar 15;11(3):e0149891,bjanto@drexelmed.edu,"Deleting all four of these genes (msfA1-4) (KO) resulted in a highly significant decrease in phagocytosis and survival in macrophages; which was fully complemented by a single copy of the msfA1 gene. Using the chinchilla model of otitis media and invasive disease, the KO strain displayed a significant decrease in fitness compared to the WT in coinfections; and in single infections, the KO lost its ability to invade the brain.",J M Kress-Bennett 2016,2016,4 genes,Kress-Bennett-2016-Identification and Characte,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8035,PHI:6153,UniProt,Q5NI41,GenBank,AJI68813,,,SCHU S4,feoB,,,,,,PHI:6154,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,ferric and ferrous iron acquisition,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,26918301,PubMed,10.1002/mbo3.342,Microbiologyopen. 2016 Feb 25,girija@virginia.edu,A deltafeoB′ deltafslAmutant that required added exogenous siderophore for growth in vitro was unable to grow within tissue culture cells and was avirulent in mice,N Pérez 2016,2016,2 genes,Perez-2016-Two parallel pathways for ferric an,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8036,PHI:6154,UniProt,Q1G4R3,GenBank,ABE27280,,,LVS,fslA,,,,,,PHI:6153,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,ferric and ferrous iron acquisition,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,26918301,PubMed,10.1002/mbo3.342,Microbiologyopen. 2016 Feb 25,girija@virginia.edu,A deltafeoB′ deltafslAmutant that required added exogenous siderophore for growth in vitro was unable to grow within tissue culture cells and was avirulent in mice,N Pérez 2016,2016,2 genes,Perez-2016-Two parallel pathways for ferric an,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8037,PHI:6155,UniProt,A0A0N7D3P4,GenBank,AKQ39447,,,Yb2,AS87_03730,,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,fibrinous serositis; caseous salpingitis; vegetative disorder,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,,acyl transferase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26928424,PubMed,10.1038/srep22438,Sci Rep. 2016 Mar 1;6:22438,yus@shvri.ac.cn,,X Wang 2016,2016,1 gene,Wang-2016-Deletion of AS87_03730 gene changed,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8038,PHI:6156,UniProt,F8U972,GenBank,AEH41996,,,,bcer,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,UDP-4-keto-6-deoxyglucose-3,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS),Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26991954,PubMed,10.1111/mpp.12398,Mol Plant Pathol. 2016 Mar 17,amirsh@ex.tau.ac.il,,L Ma 2016,2016,2 genes,Ma-2016-Genetic alteration of UDP-rhamnose met,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8039,PHI:6156,UniProt,F8U972,GenBank,AEH41996,,,,bcer,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),N9059,,,leaf,UDP-4-keto-6-deoxyglucose-3,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS),Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26991954,PubMed,10.1111/mpp.12398,Mol Plant Pathol. 2016 Mar 17,amirsh@ex.tau.ac.il,,L Ma 2016,2016,2 genes,Ma-2016-Genetic alteration of UDP-rhamnose met,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8040,PHI:6157,UniProt,F8U971,GenBank,AEH41995,,,,bcdh,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,"UDP-glucose-4,6-dehydratase",,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS),Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26991954,PubMed,10.1111/mpp.12398,Mol Plant Pathol. 2016 Mar 17,amirsh@ex.tau.ac.il,,L Ma 2016,2016,2 genes,Ma-2016-Genetic alteration of UDP-rhamnose met,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8041,PHI:6157,UniProt,F8U971,GenBank,AEH41995,,,,bcdh,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),N9059,,,leaf,"UDP-glucose-4,6-dehydratase",,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS),Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26991954,PubMed,10.1111/mpp.12398,Mol Plant Pathol. 2016 Mar 17,amirsh@ex.tau.ac.il,,L Ma 2016,2016,2 genes,Ma-2016-Genetic alteration of UDP-rhamnose met,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8042,PHI:6156,UniProt,F8U972,GenBank,AEH41996,,,,bcer,,,,,,PHI:6157,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,UDP-4-keto-6-deoxyglucose-3,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS),Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26991954,PubMed,10.1111/mpp.12398,Mol Plant Pathol. 2016 Mar 17,amirsh@ex.tau.ac.il,,L Ma 2016,2016,2 genes,Ma-2016-Genetic alteration of UDP-rhamnose met,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8043,PHI:6156,UniProt,F8U972,GenBank,AEH41996,,,,bcer,,,,,,PHI:6157,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),N9059,,,leaf,UDP-4-keto-6-deoxyglucose-3,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS),Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26991954,PubMed,10.1111/mpp.12398,Mol Plant Pathol. 2016 Mar 17,amirsh@ex.tau.ac.il,,L Ma 2016,2016,2 genes,Ma-2016-Genetic alteration of UDP-rhamnose met,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8044,PHI:6157,UniProt,F8U971,GenBank,AEH41995,,,,bcdh,,,,,,PHI:6156,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,"UDP-glucose-4,6-dehydratase",,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS),Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26991954,PubMed,10.1111/mpp.12398,Mol Plant Pathol. 2016 Mar 17,amirsh@ex.tau.ac.il,,L Ma 2016,2016,2 genes,Ma-2016-Genetic alteration of UDP-rhamnose met,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8045,PHI:6157,UniProt,F8U971,GenBank,AEH41995,,,,bcdh,,,,,,PHI:6156,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),N9059,,,leaf,"UDP-glucose-4,6-dehydratase",,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,calcofluor white; congo red; sodium dodecyl sulfate (SDS),Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,26991954,PubMed,10.1111/mpp.12398,Mol Plant Pathol. 2016 Mar 17,amirsh@ex.tau.ac.il,,L Ma 2016,2016,2 genes,Ma-2016-Genetic alteration of UDP-rhamnose met,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8046,PHI:6158,UniProt,G4N2B7,GenBank,EHA52529,,,70-15,CKS1,,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,cytokinin production,,,,reduced virulence,,no,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene disruption; gene complementation,,,RP,26900703,PubMed,10.1371/journal.ppat.1005457,PLoS Pathog. 2016 Feb 22;12(2):e1005457,jbmorel@cirad.fr,"Although cks1mutants showed normalin vitro growth and development, they were severely affected forin planta growth and virulence.",E Chanclud 2016,2016,1 gene,Chanclud-2016-Cytokinin Production by the Rice,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8047,PHI:6159,UniProt,A6RYB8,GenBank,ATG1_BOTFU,,,,BcATG1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,autophagy-related,,,,loss of pathogenicity,,no,yes,yes,,reduced,,reduced; aberrant,aberrant,no,,,,,,,gene mutation; gene complementation,,,RP,26972592,PubMed,10.1111/mpp.12396,Mol Plant Pathol. 2016 Mar 11,changjun-chen@njau.edu.cn,"Deletion of BcATG1 (deltaBcatg1) inhibited autophagosome accumulation in the vacuoles of nitrogen-starved cells. deltaBcatg1 was dramatically impaired in vegetative growth, conidiation and sclerotial formation.",W Ren 2016,2016,1 gene,Ren-2016-The autophagy-related gene BcATG1 is,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8048,PHI:6159,UniProt,A6RYB8,GenBank,ATG1_BOTFU,,,,BcATG1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,autophagy-related,,,,reduced virulence,,no,yes,yes,,reduced,,reduced; aberrant,aberrant,no,,,,,,,gene mutation; gene complementation,,,RP,26972592,PubMed,10.1111/mpp.12396,Mol Plant Pathol. 2016 Mar 11,changjun-chen@njau.edu.cn,"Deletion of BcATG1 (deltaBcatg1) inhibited autophagosome accumulation in the vacuoles of nitrogen-starved cells. deltaBcatg1 was dramatically impaired in vegetative growth, conidiation and sclerotial formation.",W Ren 2016,2016,1 gene,Ren-2016-The autophagy-related gene BcATG1 is,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8049,PHI:6159,UniProt,A6RYB8,GenBank,ATG1_BOTFU,,,,BcATG1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,autophagy-related,,,,reduced virulence,,no,yes,yes,,reduced,,reduced; aberrant,aberrant,no,,,,,,,gene mutation; gene complementation,,,RP,26972592,PubMed,10.1111/mpp.12396,Mol Plant Pathol. 2016 Mar 11,changjun-chen@njau.edu.cn,"Deletion of BcATG1 (deltaBcatg1) inhibited autophagosome accumulation in the vacuoles of nitrogen-starved cells. deltaBcatg1 was dramatically impaired in vegetative growth, conidiation and sclerotial formation.",W Ren 2016,2016,1 gene,Ren-2016-The autophagy-related gene BcATG1 is,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8050,PHI:6159,UniProt,A6RYB8,GenBank,ATG1_BOTFU,,,,BcATG1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,autophagy-related,,,,reduced virulence,,no,yes,yes,,reduced,,reduced; aberrant,aberrant,no,,,,,,,gene mutation; gene complementation,,,RP,26972592,PubMed,10.1111/mpp.12396,Mol Plant Pathol. 2016 Mar 11,changjun-chen@njau.edu.cn,"Deletion of BcATG1 (deltaBcatg1) inhibited autophagosome accumulation in the vacuoles of nitrogen-starved cells. deltaBcatg1 was dramatically impaired in vegetative growth, conidiation and sclerotial formation.",W Ren 2016,2016,1 gene,Ren-2016-The autophagy-related gene BcATG1 is,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8051,PHI:6159,UniProt,A6RYB8,GenBank,ATG1_BOTFU,,,,BcATG1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,monocots,4679,Allium cepa (related: onion),,,,fruit,autophagy-related,,,,reduced virulence,,no,yes,yes,,reduced,,reduced; aberrant,aberrant,no,,,,,,,gene mutation; gene complementation,,,RP,26972592,PubMed,10.1111/mpp.12396,Mol Plant Pathol. 2016 Mar 11,changjun-chen@njau.edu.cn,"Deletion of BcATG1 (deltaBcatg1) inhibited autophagosome accumulation in the vacuoles of nitrogen-starved cells. deltaBcatg1 was dramatically impaired in vegetative growth, conidiation and sclerotial formation.",W Ren 2016,2016,1 gene,Ren-2016-The autophagy-related gene BcATG1 is,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8052,PHI:6160,,no data found,,,,,,PST05258,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8053,PHI:6161,,no data found,,,,,,PST15391,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8054,PHI:6162,,no data found,,,,,,PST11721,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8055,PHI:6163,,no data found,,,,,,PST18220,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8056,PHI:6164,,no data found,,,,,,PST18221,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8057,PHI:6165,,no data found,,,,,,PST15642,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8058,PHI:6166,,no data found,,,,,,PST18447,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8059,PHI:6167,UniProt,A0A0L0VYD3,Ensembl Genomes,PSTG_02549,,,,PST02549,,PST02549-GFP fusion protein,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,TaEDC4-mCherry fusion protein (from Titicum aestivum: related bread wheat),UniProt: W5GVQ5; Ensembl: Traes_6DL_3FBA5B70E.1,positive co-IP,,functional test in host: transient expression,"Agrobacterium-mediated co-expression by infiltration, followed by anti-GFP co-IP",,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,"Confocal microscopy revealed that the fluorescence signals from PST02549-GFP and TaEDC4-mCherry perfectly overlapped in cytosolic foci, indicating co-accumulation in P-bodies.",B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B / AC update,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8060,PHI:6168,,no data found,,,,,,PST05023,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8061,PHI:6169,,no data found,,,,,,PST12160,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8062,PHI:6170,,no data found,,,,,,PST10977,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8063,PHI:6171,,no data found,,,,,,PST03196,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8064,PHI:6172,,no data found,,,,,,PST05302,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8065,PHI:6173,,no data found,,,,,,PST15964,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8066,PHI:6174,,no data found,,,,,,PST08468,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8067,PHI:6175,,no data found,,,,,,PST05006,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,yellow rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,26863009,PubMed,10.1371/journal.pone.0149035,PLoS One. 2016 Feb 10;11(2):e0149035,Sophien.Kamoun@tsl.ac.uk,,B Petre 2016,2016,16 genes,Petre-2016-Heterologous Expression Screens in,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8068,PHI:6176,UniProt,L7ZK02,GenBank,AGE16896,,,WW4,prodigiosin,,,,,,,615,Serratia marcescens,,SM-R,nosocomial infection,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,red pigmentation,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,27000435,PubMed,10.1016/j.jip.2016.03.011,J Invertebr Pathol. 2016 May;136:92-4,canbl3312@126.com,,W Zhou 2016,2016,1 gene,Zhou-2016-The red pigment prodigiosin is not a,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8069,PHI:6179,UniProt,A0A140CZL2,GenBank,KU170060,,,EV-MIL31,AaSSK1,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,response regulator,,,,reduced virulence,,,,,,wild type,,reduced,reduced,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26863027,PubMed,10.1371/journal.pone.0149153,PLoS One. 2016 Feb 10;11(2):e0149153,krchung@nchu.edu.tw,"The SSK1 mutants display elevated sensitivity to oxidants, fail to detoxify H2O2 effectively, induce minor necrosis on susceptible citrus leaves, and displays resistance to dicarboximide and phenylpyrrole fungicides.",P Yu 2016,2016,2 genes,Yu-2016-How the Pathogenic Fungus Alternaria a,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8070,PHI:6180,UniProt,A0A140CZL3,GenBank,KU170061,,,EV-MIL31,AaSHO1,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,26863027,PubMed,10.1371/journal.pone.0149153,PLoS One. 2016 Feb 10;11(2):e0149153,krchung@nchu.edu.tw,Deletion of SHO1 (synthetichigh osmolarity) homolog resulted in no noticeable phenotypes.,P Yu 2016,2016,2 genes,Yu-2016-How the Pathogenic Fungus Alternaria a,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8071,PHI:6181,UniProt,Q0E4W1,GenBank,CAL46260,,,SAS56,Bcmimp1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Rome,,,fruit,mitochondrial inner membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26952144,PubMed,10.3389/fmicb.2016.00213,Front Microbiol. 2016 Feb 26;7:213,epbenito@usal.es,Bcmimp1 mutants do not show obvious phenotypic differences during saprophytic growth and their infection ability was unaltered as compared to the wildtype.,D Benito-Pescador 2016,2016,1 gene,"Benito-Pescador-2016-Bcmimp1, a Botrytis ciner",BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8072,PHI:6181,UniProt,Q0E4W1,GenBank,CAL46260,,,SAS56,Bcmimp1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blanca,,,fruit,mitochondrial inner membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26952144,PubMed,10.3389/fmicb.2016.00213,Front Microbiol. 2016 Feb 26;7:213,epbenito@usal.es,Bcmimp1 mutants do not show obvious phenotypic differences during saprophytic growth and their infection ability was unaltered as compared to the wildtype.,D Benito-Pescador 2016,2016,1 gene,"Benito-Pescador-2016-Bcmimp1, a Botrytis ciner",BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8073,PHI:6183,UniProt,I1RW84,GenBank,ESU14785,,,PH-1,FgVps27,,,,FgHse1,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,"ESCRT-0 component, plays critical roles in a variety of cellular and biological processes",,,high osmolarity glycerol (HOG) response pathway,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,,no,calcofluor white; congo red,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,RP,26971885,PubMed,10.1111/1462-2920.13296,Environ Microbiol. 2016 Mar 11,wangzh@fafu.edu.cn,,Q Xie 2016,2016,1 gene,Xie-2016-ESCRT-0 complex is required for funga,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8074,PHI:6184,UniProt,P39165,GenBank,AAC74304,,,MG1655,ychO,,,,,,,562,Escherichia coli,1196033,SEPT362,colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,,invasin homolog,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,26965678,PubMed,10.1186/s12866-016-0654-2,BMC Microbiol. 2016 Mar 10;16:35,wds@unicamp.br,,L Pilatti 2016,2016,1 gene,Pilatti-2016-The virulence factor ychO has a p,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8075,PHI:6185,UniProt,Q8PRG7,,,,,306,pthA4,,none (wild-type),,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,CsLOB1,GenBank: XP_006476858,leaf,susceptibility gene for citrus canker,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: mutated transgenic plants,,,RP,27071672,PubMed,10.1111/pbi.12495,Plant Biotechnol J. 2016 May;14(5):1291-301,nianwang@ufl.edu,"Activation of a single allele of susceptibility gene CsLOB1by PthA4 is sufficient to induce citrus canker disease, and mutation in the promoters of both alleles of CsLOB1is probably required to generate citrus canker-resistant plants.",H Jia 2016,2016,1 gene,Jia-2016-Modification of the PthA4 effector bi,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8076,PHI:6186,UniProt,A0A0E0S977,EMBL,FGRAMPH1_01T22563,,,PH-1,FgCHS8,,,,,,,5518,Fusarium graminearum,,DAOM 180378,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,leaf,chitin synthase,,,,reduced virulence,,,,,,wild type,,wild type,,no,SDS; salicylic acid,SDS: CHEBI:8984; salicylic acid: CHEBI:16914,,,,,gene deletion: full; gene complementation,,,RP,27109372,PubMed,10.1016/j.funbio.2016.02.002,Fungal Biol. 2016 May;120(5):764-74,ylzheng@sicau.edu.cn,"deltaFgCHS8 had a growth rate comparable to that of the wildtype isolatein vitro. However, DFgCHS8had reduced growth when grown on agar supplemented with either 0.025% SDS or 0.9 mM salicylic acid.",Y ZHANG 2016,2016,1 gene,Zhang-2016-Chitin synthase gene FgCHS8 affects,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8077,PHI:6187,UniProt,Q8ZMF9,GenBank,AAL21806,,,LT2,pimt,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain E-2375,salmonellosis,rodents,10090,Mus musculus (related: house mouse),Swiss albino,,,spleen; liver,protein isoaspartate methyl transferase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; HOCl,H2O2: CHEBI:16240; HOCl: CHEBI:24757,,,,,gene mutation; gene complementation,,,RP,27156953,PubMed,10.1016/j.ijmm.2016.04.005,Int J Med Microbiol. 2016 Apr 29. pii: S1438-4221(16)30043-1,manish.mahawar@icar.gov.in,"The pimt strain is found significantly (p < 0.001) more susceptible to H2O2 and hypochlorite (HOCl). Further, the pimt mutant strain shows hypersusceptibility (p < 0.001) to INF- stimulated macrophages.",M Kumawat 2016,2016,1 gene,Kumawat-2016-Contribution of protein isoaspart,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8078,PHI:6188,UniProt,A0A095CIZ4,GenBank,KGB80315,,,R265,Ubp5,,,,,,,552467,Cryptococcus bacillisporus,294750,R265,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,deubiquitinase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,H2O2; NO; flucytosine; terbinafine,"H2O2: CHEBI:16240; NO: CHEBI:16480; flucytosine: CHEBI:5100; terbinafine: CHEBI:9448, CAS:91161-71-6",,,,,gene mutation; gene complementation,,,RP,27049762,PubMed,10.1371/journal.pone.0153219,PLoS One. 2016 Apr 6;11(4):e0153219,liaowanqing@sohu.com,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,Y Meng 2016,2016,1 gene,Meng-2016-Deubiquitinase Ubp5 Is Required for,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8079,PHI:6188,UniProt,A0A095CIZ4,GenBank,KGB80315,,,R265,Ubp5,,,,,,,552467,Cryptococcus bacillisporus,294750,R265,fungal meningitis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,lung; brain,deubiquitinase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,H2O2; NO; flucytosine; terbinafine,"H2O2: CHEBI:16240; NO: CHEBI:16480; flucytosine: CHEBI:5100; terbinafine: CHEBI:9448, CAS:91161-71-6",,,,,gene mutation; gene complementation,,,RP,27049762,PubMed,10.1371/journal.pone.0153219,PLoS One. 2016 Apr 6;11(4):e0153219,liaowanqing@sohu.com,pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,Y Meng 2016,2016,1 gene,Meng-2016-Deubiquitinase Ubp5 Is Required for,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8080,PHI:6189,UniProt,Q724L7,GenBank,AAT02994,,,F2365,SpoVG,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,RNA-binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27048798,PubMed,10.1128/mBio.00240-16,MBio. 2016 Apr 5;7(2). pii: e00240-16,Portnoy@berkeley.edu,SpoVG rescued lysozyme sensitivity and attenuation in vivo of the rli31 mutant,T P Burke 2016,2016,1 gene,Burke-2016-SpoVG Is a Conserved RNA-Binding Pr,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8081,PHI:6190,UniProt,Q5HDJ0,GenBank,AGY90568,,,Z172,Mqo,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,malate-quinone oxidoreductases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26851155,PubMed,10.1111/mmi.13347,Mol Microbiol. 2016 Jun;100(5):759-73,richardson@pitt.edu,The contribution of each of these enzymes to virulence is not additive in that the double DmqoDlqo mutant was equivalently attenuated as each single mutant.,N A Spahich 2016,2016,1 gene,Spahich-2016-Staphylococcus aureus lactate- an,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8082,PHI:6191,UniProt,Q5HCU5,GenBank,AAW38622,,,COL,Lqo,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,L-lactate-quinone oxidoreductases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26851155,PubMed,10.1111/mmi.13347,Mol Microbiol. 2016 Jun;100(5):759-73,richardson@pitt.edu,The contribution of each of these enzymes to virulence is not additive in that the double DmqoDlqo mutant was equivalently attenuated as each single mutant.,N A Spahich 2016,2016,1 gene,Spahich-2016-Staphylococcus aureus lactate- an,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8083,PHI:6190,UniProt,Q5HDJ0,GenBank,AGY90568,,,Z172,Mqo,,,,,,PHI:6191,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,malate-quinone oxidoreductases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26851155,PubMed,10.1111/mmi.13347,Mol Microbiol. 2016 Jun;100(5):759-73,richardson@pitt.edu,The contribution of each of these enzymes to virulence is not additive in that the double DmqoDlqo mutant was equivalently attenuated as each single mutant.,N A Spahich 2016,2016,1 gene,Spahich-2016-Staphylococcus aureus lactate- an,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8084,PHI:6191,UniProt,Q5HCU5,GenBank,AAW38622,,,COL,Lqo,,,,,,PHI:6190,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,L-lactate-quinone oxidoreductases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26851155,PubMed,10.1111/mmi.13347,Mol Microbiol. 2016 Jun;100(5):759-73,richardson@pitt.edu,The contribution of each of these enzymes to virulence is not additive in that the double DmqoDlqo mutant was equivalently attenuated as each single mutant.,N A Spahich 2016,2016,1 gene,Spahich-2016-Staphylococcus aureus lactate- an,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8085,PHI:6192,UniProt,Q9P8Q7,GenBank,AF222905_1,,,,CaIcl1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cecum,isocitrate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27073846,PubMed,10.1371/journal.ppat.1005566,PLoS Pathog. 2016 Apr 13;12(4):e1005566,al.brown@abdn.ac.uk,,D S Childers 2016,2016,2 genes,Childers-2016-The Rewiring of Ubiquitination T,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8086,PHI:6193,UniProt,P40208,GenBank,CAA87349,,,AB972,GID8,,,,,,,4932,Saccharomyces cerevisiae,,NCPF8313,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),DBA/2,,,cecum,glucose-induced degradation protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27073846,PubMed,10.1371/journal.ppat.1005566,PLoS Pathog. 2016 Apr 13;12(4):e1005566,al.brown@abdn.ac.uk,,D S Childers 2016,2016,2 genes,Childers-2016-The Rewiring of Ubiquitination T,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8087,PHI:6194,UniProt,Q72RB2,GenBank,AAS70422,,,L1-130,fliM,chromosome I,,,,,,173,Leptospira interrogans,,702,leptospirosis,rodents,10026,Cricetinae (related: hamsters),,,,,flagellar motor switch protein,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27044038,PubMed,10.1371/journal.pone.0152916,PLoS One. 2016 Apr 4;11(4):e0152916,mathieu.picardeau@pasteur.fr,"Genetic complementation restored cell morphology, motility and virulence comparable to those of wild type cells.",C Fontana 2016,2016,1 gene,Fontana-2016-Analysis of a Spontaneous Non-Mot,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8088,PHI:6195,,no data found,,,,,,PAI-536,,All 7 pathogenicity islands deleted,,,,,562,Escherichia coli,362663,536,pyelonephritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,pathogenicity islands,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27096607,PubMed,10.1371/journal.pone.0153034,PLoS One. 2016 Apr 20;11(4):e0153034,jerome.tourret@psl.aphp.fr,All 7 pathogenicity islands were deleted.,J Tourret 2016,2016,1 gene,Tourret-2016-Small Intestine Early Innate Immu,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8089,PHI:6196,UniProt,E7DX61,GenBank,ADR82212,,,1-a-1,Adh,,,,,,,715,Actinobacillus pleuropneumoniae,416269,serotype 5b strain L20,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,trimeric autotransporter adhesin,,,MAP kinase signaling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27046446,PubMed,10.1038/srep24058,Sci Rep. 2016 Apr 5;6:24058,leilc@jlu.edu.cn,"We found that Adh was shown to interact with theporcine alveolar macrophages membrane protein OR5M11, an olfactory receptor, resulting in the high-level secretion of IL-8 by activation of p38 MAPK signaling pathway.",L Wang 2016,2016,1 gene,Wang-2016-Adh enhances Actinobacillus pleuropn,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8090,PHI:6196,UniProt,E7DX61,GenBank,ADR82212,,,1-a-1,Adh,,,,,,,715,Actinobacillus pleuropneumoniae,416269,serotype 5b strain L20,pneumonia,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,lung,trimeric autotransporter adhesin,,,MAP kinase signaling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27046446,PubMed,10.1038/srep24058,Sci Rep. 2016 Apr 5;6:24058,leilc@jlu.edu.cn,"We found that Adh was shown to interact with theporcine alveolar macrophages membrane protein OR5M11, an olfactory receptor, resulting in the high-level secretion of IL-8 by activation of p38 MAPK signaling pathway.",L Wang 2016,2016,1 gene,Wang-2016-Adh enhances Actinobacillus pleuropn,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8091,PHI:6197,,no data found,GenBank,XP_001548410,,,B05.10,BcIqg1,,,,BcNoxD; BcRac,"BcRac, UniProt: G2YY48",,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,scaffold protein,,,,reduced virulence,,no,yes,yes,,reduced,,,,no,H2O2; menadione; calcoflour white,H2O2: CHEBI:16240; menadione: CHEBI:28869; calcoflour white: CHEBI:50011,,,,,gene mutation; gene complementation,,,RP,27062300,PubMed,10.1111/mmi.13391,Mol Microbiol. 2016 Apr 7,tudzyns@uni-muenster.de,"BcIqg1 interacts directly with a cytosolic, regulatory component (BcRac) and a membrane associated subunit (BcNoxD) of a Nox-complex in the pathogen Botrytis cinerea.",R Marschall 2016,2016,1 gene,"Marschall-2016-BcIqg1, a fungal IQGAP homolog",BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8092,PHI:6198,UniProt,A0A098DGQ1,EMBL,FGRAMPH1_01T10657,,,PH-1,SOD1,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,superoxide dismutases,,,,reduced virulence,,,,,,,,reduced,reduced; aberrant,no,H2O2; SDS; Congo red; calcoflour white; NaCl; menadione,H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; SDS: CHEBI:8984; calcoflour white: CHEBI:50011; NaCl: CHEBI:26710; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,RP,27037138,PubMed,10.1016/j.fgb.2016.03.006,Fungal Genet Biol. 2016 Jun;91:32-42,whtang@sibs.ac.cn,The Dsod1 mutants had slightly reduced hyphal growth and markedly increased sensitivity to the intracellular ROS generator menadione.,S Yao 2016,2016,1 gene,Yao-2016-A cytoplasmic Cu-Zn superoxide dismut,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8093,PHI:6199,UniProt,Q86ZF8,GenBank,AAN39296,,,,BbCypA,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8094,PHI:6200,,no data found,,,,,,BbCyp3,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8095,PHI:6201,,no data found,,,,,,BbCypX,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8096,PHI:6202,,no data found,,,,,,BbCypB,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8097,PHI:6203,,no data found,,,,,,BbCypD,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8098,PHI:6204,,no data found,,,,,,BbCypH,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,unaffected pathogenicity,,,,,,increased,,wild type,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8099,PHI:6205,UniProt,I1ZIP1,GenBank,AFJ24915,,,,BbCypE,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8100,PHI:6206,UniProt,F5B5Y4,GenBank,AEE02052,,,,BbCypC,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8101,PHI:6207,UniProt,I1V1W1,GenBank,AFI25171,,,,BbCyp6,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,reduced virulence,,,,,,reduced,,wild type,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8102,PHI:6208,UniProt,I1ZIP0,GenBank,AFJ24914,,,,BbCyp8,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8103,PHI:6209,UniProt,I1ZIN3,GenBank,AFJ24907,,,,BbCyp9,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cyclophilin,,,,unaffected pathogenicity,,,,,,increased,,reduced,,no,sorbitol; Congo red,D-sorbitol: CHEBI:17924; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27130487,PubMed,10.1111/1462-2920.13339,Environ Microbiol. 2016 Apr 30,peiyan3@swu.edu.cn,,Y Zhou 2016,2016,11 genes,Zhou-2016-Dissection of the contributions of c,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8104,PHI:6210,UniProt,D0ZCA6,GenBank,ACY85445,,,EIB202,Fur,,,,,,,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,52904,Scophthalmus maximus (related: Turbot),,,,,transcriptional regulator/ ferric uptake regulator,,,,reduced virulence,,,,,,increased,,aberrant,,no,H2O2; MnCl2,H2O2: CHEBI:16240; MnCl2: CHEBI:63041,,,,,gene mutation; gene complementation,,,RP,27102497,PubMed,10.1016/j.jprot.2016.04.005,J Proteomics. 2016 May 17;140:100-10,lsun@qdio.ac.cn,"Compared to the wild type TX01, thefurmutant TX01deltafurexhibited (i) retarded growth, (ii) enhanced siderophore production, (iii) increased acid tolerance, which is in contrast to observations in other bacterial species, (iv) decreased survival against oxidative stress and host serum, (v) impaired ability to inhibit host immune response, (vi) attenuated tissue infectivity and overall virulence.",Y Hu 2016,2016,1 gene,Hu-2016-The global regulatory effect of Edward,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8105,PHI:6211,UniProt,Q9I0P9,GenBank,AE004687_5,,,PAO1,CdpR,,,,ClpS,UniProt: Q9I0L7,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27119725,PubMed,10.1371/journal.pbio.1002449,PLoS Biol. 2016 Apr 27;14(4):e1002449,lianghh@nwu.edu.cn,,J Zhao 2016,2016,3 genes,Zhao-2016-Structural and Molecular Mechanism o,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8106,PHI:6212,UniProt,Q9I0L7,GenBank,AE004690_9,,,PAO1,clpS/clpA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,adapter protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27119725,PubMed,10.1371/journal.pbio.1002449,PLoS Biol. 2016 Apr 27;14(4):e1002449,lianghh@nwu.edu.cn,,J Zhao 2016,2016,3 genes,Zhao-2016-Structural and Molecular Mechanism o,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8107,PHI:6213,UniProt,Q9I2U1,GenBank,AE004606_4,,,PAO1,clpP,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,ATP-dependent Clp protease proteolytic subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27119725,PubMed,10.1371/journal.pbio.1002449,PLoS Biol. 2016 Apr 27;14(4):e1002449,lianghh@nwu.edu.cn,,J Zhao 2016,2016,3 genes,Zhao-2016-Structural and Molecular Mechanism o,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8108,PHI:6214,UniProt,Q59UR2,GenBank,EAK94222,,,SC5314,MNN10,chromosome 4,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney; liver,"alpha-1,6-mannosyltransferase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27144456,PubMed,10.1371/journal.ppat.1005617,PLoS Pathog. 2016 May 4;12(5):e1005617,jiangyy@tongji.edu.cn,,S Q Zhang 2016,2016,1 gene,Zhang-2016-Mnn10 Maintains Pathogenicity in Ca,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8109,PHI:6214,UniProt,Q59UR2,GenBank,EAK94222,,,SC5314,MNN10,chromosome 4,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/cByJSlacc,,,kidney; liver,"alpha-1,6-mannosyltransferase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27144456,PubMed,10.1371/journal.ppat.1005617,PLoS Pathog. 2016 May 4;12(5):e1005617,jiangyy@tongji.edu.cn,,S Q Zhang 2016,2016,1 gene,Zhang-2016-Mnn10 Maintains Pathogenicity in Ca,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8110,PHI:6215,UniProt,Q5A2U0,GenBank,EAK96948,,,SC5314,Aif1,chromosome 2,,,,,,5476,Candida albicans,,DAY1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,apoptosis inducing factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; acetic acid; caspofungin,H2O2: CHEBI:16240; acetic acid: CHEBI:15366; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,RP,27121326,PubMed,10.1002/yea.3167,Yeast. 2016 Apr 28,yuqilin7007@163.com,"Deletion of AIF1 causes attenuated apoptosis in this pathogen under apoptosis-inducing conditions, such as the treatment of 2 mM H2O2, 10 mM acetic acid or 0.08 mg/L caspofungin, and its overexpression enhances this process.",F Ma 2016,2016,1 gene,Ma-2016-Role of Aif1 in regulation of cell dea,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8111,PHI:6215,UniProt,Q5A2U0,GenBank,EAK96948,,,SC5314,Aif1,chromosome 2,,,,,,5476,Candida albicans,,DAY1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,apoptosis inducing factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; acetic acid; caspofungin,H2O2: CHEBI:16240; acetic acid: CHEBI:15366; caspofungin: CHEBI:474180,,,,,altered gene expression / gene regulation: overexpression,,,RP,27121326,PubMed,10.1002/yea.3167,Yeast. 2016 Apr 28,yuqilin7007@163.com,"Deletion of AIF1 causes attenuated apoptosis in this pathogen under apoptosis-inducing conditions, such as the treatment of 2 mM H2O2, 10 mM acetic acid or 0.08 mg/L caspofungin, and its overexpression enhances this process.",F Ma 2016,2016,1 gene,Ma-2016-Role of Aif1 in regulation of cell dea,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8112,PHI:6216,UniProt,S7UPL7,GenBank,EPR59946,,,GT1,FIKK,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,FIKK kinases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26859096,PubMed,10.1016/j.ijpara.2016.01.001,Int J Parasitol. 2016 May;46(5-6):323-32,Dana_Mordue@nymc.edu,"Deletion of TgFIKK, surprisingly, had no detectable effect on the parasite's lytic cycle in vitro in human fibroblast cells or in acute virulence in vivo.",S. Skariah 2016,2016,1 gene,Skariah-2016-The FIKK kinase of Toxoplasma gon,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8113,PHI:6217,UniProt,P15795,GenBank,AAA27549,,,,ToxR,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine,Cholera toxin transcriptional activator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27070545,PubMed,10.1371/journal.ppat.1005570,PLoS Pathog. 2016 Apr 12;12(4):e1005570,bwdavies@austin.utexas.edu,"In the absence of H-NS, ToxR is no longer required forV.choleraeto colonize the infant mouse intestine or for robust biofilm formation.",M I Kazi 2016,2016,1 gene,Kazi-2016-ToxR Antagonizes H-NS Regulation of,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8114,PHI:6218,UniProt,Q9KVH0,GenBank,AAF93352,,,N16961,VC0176,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27070545,PubMed,10.1371/journal.ppat.1005570,PLoS Pathog. 2016 Apr 12;12(4):e1005570,bwdavies@austin.utexas.edu,"In the absence of H-NS, ToxR is no longer required forV.choleraeto colonize the infant mouse intestine or for robust biofilm formation.",M I Kazi 2016,2016,1 gene,Kazi-2016-ToxR Antagonizes H-NS Regulation of,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8115,PHI:6219,UniProt,A0A085TMV5,GenBank,KFE32052,,,523-80,hns,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine,histone-like nucleoid structuring protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27070545,PubMed,10.1371/journal.ppat.1005570,PLoS Pathog. 2016 Apr 12;12(4):e1005570,bwdavies@austin.utexas.edu,"In the absence of H-NS, ToxR is no longer required forV.choleraeto colonize the infant mouse intestine or for robust biofilm formation.",M I Kazi 2016,2016,1 gene,Kazi-2016-ToxR Antagonizes H-NS Regulation of,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8116,PHI:6220,UniProt,P0C053,GenBank,SBG60102,,,MSSA,essB,,,,,,,1280,Staphylococcus aureus,523796,ST398,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin; kidney; blood,component of the ESAT-6 secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27112266,PubMed,10.1038/srep25163,Sci Rep. 2016 Apr 26;6:25163,ruth_limin@126.com,Deletion of essBin ST398 resulted in significantly reduced resistance to neutrophil killing and decreased virulence in murine skin and blood infection models.,Y Wang 2016,2016,1 gene,Wang-2016-Role of the ESAT-6 secretion system,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8117,PHI:6221,UniProt,Q8Y9L3,GenBank,CAC98593,,,EGD-e,Lmo0514,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27085096,PubMed,10.1111/1758-2229.12416,Environ Microbiol Rep. 2016 Apr 16,mg.pucciarelli@uam.es,"Lmo0514, induced by L. monocytogenes inside epithelial cells,is required for survival in plasma and for virulence in mice at early infection stages.",J J Quereda 2016,2016,1 gene,Quereda-2016-Listeria monocytogenes remodels t,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8118,PHI:6222,,no data found,,,,,,SS9-LysM,,,,,,,1307,Streptococcus suis,,GZ0565,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),SPF CD-1,,,blood; liver; spleen; brain,surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27066710,PubMed,10.1016/j.vetmic.2016.03.017,Vet Microbiol. 2016 May 1;187:64-9,lucp@njau.edu.cn,,Z Wu 2016,2016,1 gene,Wu-2016-A Streptococcus suis LysM domain surfa,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8119,PHI:6223,UniProt,G4NAJ8,GenBank,EHA51336,,,70-15,MoYvh1,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,protein phosphatase,,,MAPK pathway,reduced virulence,,yes,yes,yes,,reduced,,reduced,,no,butanediamide; rose bengal sodium salt; potassium peroxide (KO2); hydrogen peroxide (H2O2),rose bengal sodium salt: CHEBI:52261; potassium peroxide (KO2) CAS number: CAS:17014-71-0; hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,27110741,PubMed,10.1094/MPMI-11-15-0259-R,Mol Plant Microbe Interact. 2016 Jun;29(6):496-507,zhgzhang@njau.edu.cn,"Deletion of the MoYVH1 gene resulted in significant reductions in vegetative growth, conidial production, and virulence. TheDMoyvh1mutant also displayed defects in cell-wall integrity and was hyposensitive to the exogenous osmotic stress. Further examination revealed that the DMoyvh1 mutant had defects in appressorium function and invasive hyphae growth, resulting attenuated pathogenicity.",X Liu 2016,2016,1 gene,Liu-2016-The Putative Protein Phosphatase MoYv,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8120,PHI:6224,UniProt,G7TEV4,GenBank,AEQ96469,,,BLS256,XOC_2335,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,GGDEF-EAL domain proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27053282,PubMed,10.1038/srep23769,Sci Rep. 2016 Apr 7;6:23769,wxs@cau.edu.cn,,C Wei 2016,2016,3 genes,Wei-2016-A systematic analysis of the role of,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8121,PHI:6225,UniProt,G7TFG9,GenBank,AEQ96526,,,BLS256,XOC_2393,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,GGDEF-EAL domain proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27053282,PubMed,10.1038/srep23769,Sci Rep. 2016 Apr 7;6:23769,wxs@cau.edu.cn,,C Wei 2016,2016,3 genes,Wei-2016-A systematic analysis of the role of,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8122,PHI:6224,UniProt,G7TEV4,GenBank,AEQ96469,,,BLS256,XOC_2335,,,,,,PHI:6225,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,GGDEF-EAL domain proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27053282,PubMed,10.1038/srep23769,Sci Rep. 2016 Apr 7;6:23769,wxs@cau.edu.cn,,C Wei 2016,2016,3 genes,Wei-2016-A systematic analysis of the role of,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8123,PHI:6225,UniProt,G7TFG9,GenBank,AEQ96526,,,BLS256,XOC_2393,,,,,,PHI:6224,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,GGDEF-EAL domain proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27053282,PubMed,10.1038/srep23769,Sci Rep. 2016 Apr 7;6:23769,wxs@cau.edu.cn,,C Wei 2016,2016,3 genes,Wei-2016-A systematic analysis of the role of,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8124,PHI:6226,UniProt,G7TKC9,GenBank,AEQ98268,,,BLS256,XOC_4190,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,GGDEF-EAL domain proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27053282,PubMed,10.1038/srep23769,Sci Rep. 2016 Apr 7;6:23769,wxs@cau.edu.cn,,C Wei 2016,2016,3 genes,Wei-2016-A systematic analysis of the role of,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8125,PHI:6227,UniProt,E3QHX9,GenBank,EFQ30467,,,M1.001,KRE5,,,,,,,31870,Colletotrichum graminicola,,M2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf,"beta-1,6-glucan synthesis",,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27144995,PubMed,10.1111/tpj.13205,Plant J. 2016 May 3,holger.deising@landw.uni-halle.de,"Average rates of homologous integration in C. graminicola are usually above 30%, these results strongly suggest that deletion of KRE5 or KRE6 is lethal.",E Oliveira-Garcia 2016,2016,2 genes,Oliveira-Garcia-2016-Attenuation of PAMP-trigg,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8126,PHI:6228,UniProt,E3QNW8,GenBank,EFQ32556,,,M1.001,KRE6,,,,,,,31870,Colletotrichum graminicola,,M2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf,"beta-1,6-glucan synthesis",,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,yes,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27144995,PubMed,10.1111/tpj.13205,Plant J. 2016 May 3,holger.deising@landw.uni-halle.de,"Average rates of homologous integration in C. graminicola are usually above 30%, these results strongly suggest that deletion of KRE5 or KRE6 is lethal.",E Oliveira-Garcia 2016,2016,2 genes,Oliveira-Garcia-2016-Attenuation of PAMP-trigg,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8127,PHI:6229,,no data found,GenBank,CAR34536,,,P125109,SEN2960,,,,,,PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8128,PHI:6230,,no data found,GenBank,CAR34538,,,P125109,SEN2962,,,,,,PHI:6229; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8129,PHI:6231,,no data found,GenBank,CAR34540,,,P125109,SEN2964,,,,,,PHI:6229; PHI:6230; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8130,PHI:6232,,no data found,GenBank,CAR34541,,,P125109,SEN2965,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8131,PHI:6233,,no data found,GenBank,CAR34542,,,P125109,SEN2966,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8132,PHI:6234,,no data found,GenBank,CAR34544,,,P125109,SEN2968,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8133,PHI:6235,,no data found,GenBank,CAR34546,,,P125109,SEN2970,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8134,PHI:6236,,no data found,GenBank,CAR34548,,,P125109,SEN2972,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8135,PHI:6237,,no data found,GenBank,CAR34550,,,P125109,SEN2974,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8136,PHI:6238,,no data found,GenBank,CAR34551,,,P125109,SEN2975,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8137,PHI:6239,,no data found,GenBank,CAR34553,,,P125109,SEN2977,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,pathogenicity island,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8138,PHI:6229,,no data found,GenBank,CAR34536,,,P125109,SEN2960,,,,,,PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8139,PHI:6230,,no data found,GenBank,CAR34538,,,P125109,SEN2962,,,,,,PHI:6229; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8140,PHI:6231,,no data found,GenBank,CAR34540,,,P125109,SEN2964,,,,,,PHI:6229; PHI:6230; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8141,PHI:6232,,no data found,GenBank,CAR34541,,,P125109,SEN2965,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8142,PHI:6233,,no data found,GenBank,CAR34542,,,P125109,SEN2966,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8143,PHI:6234,,no data found,GenBank,CAR34544,,,P125109,SEN2968,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6235; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8144,PHI:6235,,no data found,GenBank,CAR34546,,,P125109,SEN2970,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6236; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8145,PHI:6236,,no data found,GenBank,CAR34548,,,P125109,SEN2972,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6237; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8146,PHI:6237,,no data found,GenBank,CAR34550,,,P125109,SEN2974,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6238; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8147,PHI:6238,,no data found,GenBank,CAR34551,,,P125109,SEN2975,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6239,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8148,PHI:6239,,no data found,GenBank,CAR34553,,,P125109,SEN2977,,,,,,PHI:6229; PHI:6230; PHI:6231; PHI:6232; PHI:6233; PHI:6234; PHI:6235; PHI:6236; PHI:6237; PHI:6238,28901,Salmonella enterica,886715,subsp. enterica serovar Enteritidis strain CDC_2010K_0968,gastroenteritis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; cecum,pathogenicity island,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27141235,PubMed,10.1186/s13099-016-0098-0,Gut Pathog. 2016 May 2;8:16,dshah@vetmed.wsu.edu,"The deletion of the SPI-13 resulted in impaired infection kinetics of S.Enteritidis in streptomycin pre-treated mice which was characterized by significantly lower (P < 0.05) viable counts in the ceca, liver and spleen, impaired ability to induce intestinal inflammation and reduced survival within murine macrophages. Conversely, there were no significant differences in the infection kinetics of deltaSPI-13 in day-old chickens in any of the organs tested and the survival of deltaSPI-13 within chicken macrophages remained unaltered.",J R Elder 2016,2016,11 genes,Elder-2016-The Salmonella pathogenicity island,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8149,PHI:6240,UniProt,J9VU22,GenBank,AFR95235,,,H99,Zip1,,,,,,,5207,Cryptococcus neoformans,,,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,ZIP family zinc transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27118799,PubMed,10.1093/mmy/myw013,Med Mycol. 2016 Apr 26. pii: myw013,whjung@cau.ac.kr,"Mutant lacking ZIP1displayed a severe growth defect under zinc-limited conditions, while the mutant lackingZIP2displayed normal growth.",E Do 2016,2016,2 genes,Do-2016-The ZIP family zinc transporters suppo,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8150,PHI:6241,UniProt,J9VT75,GenBank,AFR96621,,,H99,Zip2,,,,,,,5207,Cryptococcus neoformans,,,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,ZIP family zinc transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27118799,PubMed,10.1093/mmy/myw013,Med Mycol. 2016 Apr 26. pii: myw013,whjung@cau.ac.kr,"Mutant lacking ZIP1displayed a severe growth defect under zinc-limited conditions, while the mutant lackingZIP2displayed normal growth.",E Do 2016,2016,2 genes,Do-2016-The ZIP family zinc transporters suppo,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8151,PHI:6240,UniProt,J9VU22,GenBank,AFR95235,,,H99,Zip1,,,,,,PHI:6241,5207,Cryptococcus neoformans,,,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,ZIP family zinc transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27118799,PubMed,10.1093/mmy/myw013,Med Mycol. 2016 Apr 26. pii: myw013,whjung@cau.ac.kr,"Mutant lacking ZIP1displayed a severe growth defect under zinc-limited conditions, while the mutant lackingZIP2displayed normal growth.",E Do 2016,2016,2 genes,Do-2016-The ZIP family zinc transporters suppo,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8152,PHI:6241,UniProt,J9VT75,GenBank,AFR96621,,,H99,Zip2,,,,,,PHI:6240,5207,Cryptococcus neoformans,,,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,ZIP family zinc transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27118799,PubMed,10.1093/mmy/myw013,Med Mycol. 2016 Apr 26. pii: myw013,whjung@cau.ac.kr,"Mutant lacking ZIP1displayed a severe growth defect under zinc-limited conditions, while the mutant lackingZIP2displayed normal growth.",E Do 2016,2016,2 genes,Do-2016-The ZIP family zinc transporters suppo,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8153,PHI:6242,,no data found,,PA1S_06925,,,PA1,hicA,,,,,,PHI:6243,287,Pseudomonas aeruginosa,1279007,PA1,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,part of the toxin-antitoxin system,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,27104566,PubMed,10.3390/toxins8040113,Toxins (Basel). 2016 Apr 19;8(4). pii: E113,liming@tmmu.edu.cn,Deletion of hicAB had no effect on the biofilm formation and virulence of P. aeruginosa in a mice infection model.,G Li 2016,2016,2 genes,Li-2016-Identification and Characterization of,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8154,PHI:6243,,no data found,,PA1S_06920,,,PA1,hicB,,,,,,PHI:6242,287,Pseudomonas aeruginosa,1279007,PA1,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,part of the toxin-antitoxin system,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,27104566,PubMed,10.3390/toxins8040113,Toxins (Basel). 2016 Apr 19;8(4). pii: E113,liming@tmmu.edu.cn,Deletion of hicAB had no effect on the biofilm formation and virulence of P. aeruginosa in a mice infection model.,G Li 2016,2016,2 genes,Li-2016-Identification and Characterization of,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8155,PHI:6244,,no data found,,,,,,Usv101,,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; brain; spleen,master regulator of pathogenesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27094327,PubMed,10.1128/mBio.00313-16,MBio. 2016 Apr 19;7(2). pii: e00313-16,doering@wustl.edu,"Murine infection with cryptococci lacking Usv101 significantly alters the kinetics and pathogenesis of disease, with extended survival and, unexpectedly, death by pneumonia rather than meningitis.",S R Gish 2016,2016,1 gene,Gish-2016-Computational Analysis Reveals a Key,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8156,PHI:6245,UniProt,I1RTG5,GenBank,CEF82910,,,PH-1,FaMyo2B,chromosome 4,,,,,,5518,Fusarium graminearum,,2021,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 5,,,spikelet,myosin proteins,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,phenamacril,,,,,,gene disruption; gene complementation,,,RP,27099966,PubMed,10.1371/journal.pone.0154058,PLoS One. 2016 Apr 21;11(4):e0154058,mgzhou@njau.edu.cn,FaMyo2B acts jointly withFaSmy1to affect resistance to phenamacril inF.asiaticum.,Z Zheng 2016,2016,2 genes,Zheng-2016-Myosins FaMyo2B and Famyo2 Affect A,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8157,PHI:6246,UniProt,A0A098DDX5,EMBL,FGRAMPH1_01T10651,,,PH-1,Famyo2,,,,,,,5518,Fusarium graminearum,,2021,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 5,,,spikelet,myosin proteins,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,phenamacril,,,,,,gene mutation; gene complementation,,,RP,27099966,PubMed,10.1371/journal.pone.0154058,PLoS One. 2016 Apr 21;11(4):e0154058,mgzhou@njau.edu.cn,,Z Zheng 2016,2016,2 genes,Zheng-2016-Myosins FaMyo2B and Famyo2 Affect A,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8158,PHI:6247,,no data found,,,,,,BSR0441,chromosome 2,,,,,,29459,Brucella melitensis,224914,16M,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,small noncoding RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27112796,PubMed,10.1038/srep25123,Sci Rep. 2016 Apr 26;6:25123,zeliangchen@yahoo.com,The deletion mutant of BSR0441 (a small noncoding RNA (sRNA) showed significantly reduced spleen colonization in the middle and late phases of infection.,Z Zhong 2016,2016,1 gene,Zhong-2016-Large-scale identification of small,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8159,PHI:6248,UniProt,A0A0K9N568,GenBank,KMZ51693,,,UM139,Fut2,,,,,,,210,Helicobacter pylori,,17875/Leb23,gastric infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,Muc5ac,UniProt: E9PWB6,stomach,"alpha 1,2-fucosyltransferase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27161092,PubMed,10.1038/srep25575,Sci Rep. 2016 May 10;6:25575,celsor@ipatimup.pt,"Loss of mucin FUT2-mediated fucosylation impairs gastric mucosal binding of H. pylori BabA adhesin, which is a recognized feature of pathogenicity",A Magalhães 2016,2016,1 gene,Magalhaes-2016-Muc5ac gastric mucin glycosylat,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8160,PHI:6249,UniProt,B2HKK6,GenBank,CDM74374,,,E11,MMAR_0242,,,,,,,1781,Mycobacterium marinum,1131442,E11,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,PE_PGRS protein,,,,reduced virulence,,,,,,,,,,no,rifampicin; erythromycin; chloramphenicol,rifampicin: CHEBI:28077; erythromycin: CHEBI:48923; chloramphenicol: CHEBI:17698,,,,,gene mutation; gene complementation,,,RP,27120981,PubMed,10.1111/cmi.12606,Cell Microbiol. 2016 Apr 28,laurent.kremer@cpbs.cnrs.fr,MMAR_0242 is required for full virulence of M. marinum and sufficient to confer pathogenic properties to M. Smegmatis.,V K Singh,2016,1 gene,Singh-2016-A unique PE_PGRS protein inhibiting,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8161,PHI:6249,UniProt,B2HKK6,GenBank,CDM74374,,,E11,MMAR_0242,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,PE_PGRS protein,,,,reduced virulence,,,,,,,,,,no,rifampicin; erythromycin; chloramphenicol,rifampicin: CHEBI:28077; erythromycin: CHEBI:48923; chloramphenicol: CHEBI:17698,,,,,gene mutation; gene complementation,,,RP,27120981,PubMed,10.1111/cmi.12606,Cell Microbiol. 2016 Apr 28,laurent.kremer@cpbs.cnrs.fr,MMAR_0242 is required for full virulence of M. marinum and sufficient to confer pathogenic properties to M. Smegmatis.,V K Singh,2016,1 gene,Singh-2016-A unique PE_PGRS protein inhibiting,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8162,PHI:6249,UniProt,B2HKK6,GenBank,CDM74374,,,E11,MMAR_0242,,,,,,,1781,Mycobacterium marinum,1131442,E11,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,PE_PGRS protein,,,,reduced virulence,,,,,,,,,,no,rifampicin; erythromycin; chloramphenicol,rifampicin: CHEBI:28077; erythromycin: CHEBI:48923; chloramphenicol: CHEBI:17698,,,,,gene mutation; gene complementation,,,RP,27120981,PubMed,10.1111/cmi.12606,Cell Microbiol. 2016 Apr 28,laurent.kremer@cpbs.cnrs.fr,MMAR_0242 is required for full virulence of M. marinum and sufficient to confer pathogenic properties to M. Smegmatis.,V K Singh,2016,1 gene,Singh-2016-A unique PE_PGRS protein inhibiting,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8163,PHI:6249,UniProt,B2HKK6,GenBank,CDM74374,,,E11,MMAR_0242,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,PE_PGRS protein,,,,reduced virulence,,,,,,,,,,no,rifampicin; erythromycin; chloramphenicol,rifampicin: CHEBI:28077; erythromycin: CHEBI:48923; chloramphenicol: CHEBI:17698,,,,,gene mutation; gene complementation,,,RP,27120981,PubMed,10.1111/cmi.12606,Cell Microbiol. 2016 Apr 28,laurent.kremer@cpbs.cnrs.fr,MMAR_0242 is required for full virulence of M. marinum and sufficient to confer pathogenic properties to M. Smegmatis.,V K Singh,2016,1 gene,Singh-2016-A unique PE_PGRS protein inhibiting,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8164,PHI:6250,UniProt,P0A917,GenBank,AAA66329,,,MG1655,OmpX,,,,,,,562,Escherichia coli,,PPECC42,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; liver; spleen; lung; kidney,outer membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27149893,PubMed,10.1292/jvms.16-0071,J Vet Med Sci. 2016 Apr 28,lishaowen@mail.hzau.edu.cn,,X MENG 2016,2016,1 gene,Meng-2016-Virulence characteristics of extrain,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8165,PHI:6251,UniProt,O24928,GenBank,AAD07172,,,26695,HP0102,,,,,,,210,Helicobacter pylori,563041,G27,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,glycosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27056952,PubMed,10.1093/infdis/jiw139,Infect Dis. 2016 Apr 7. pii: jiw139,rukhsana@iicb.res.in,deltaHP0102 mutant exhibited low acid-escape response that might account for the poor colonization efficiency of the mutant.,S Bhattacharya 2016,2016,1 gene,Bhattacharya-2016-A Conserved Helicobacter pyl,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8166,PHI:6252,UniProt,Q56889,GenBank,CAA88188,,,W1024 (serotype O:9),Inv,,,,,,,630,Yersinia enterocolitica,34054,serotype O:8,yersiniosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6JOlaHsd,,,intestine; spleen,invasin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27107739,PubMed,10.1016/j.ijmm.2016.04.002,Int J Med Microbiol. 2016 Apr 19. pii: S1438-4221(16)30040-6,stella.autenrieth@med.uni-tuebingen.de,,D Drechsler-Hake 2016,2016,2 genes,Drechsler-Hake-2016-Mononuclear phagocytes con,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8167,PHI:6253,UniProt,P31489,GenBank,CAA32086,,,6471/76 (serotype O:3),YadA,,,,,,,630,Yersinia enterocolitica,34054,serotype O:8,yersiniosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6JOlaHsd,,,intestine; spleen,adhesion,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27107739,PubMed,10.1016/j.ijmm.2016.04.002,Int J Med Microbiol. 2016 Apr 19. pii: S1438-4221(16)30040-6,stella.autenrieth@med.uni-tuebingen.de,,D Drechsler-Hake 2016,2016,2 genes,Drechsler-Hake-2016-Mononuclear phagocytes con,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8168,PHI:6252,UniProt,Q56889,GenBank,CAA88188,,,W1024 (serotype O:9),Inv,,,,,,,630,Yersinia enterocolitica,34054,serotype O:8,yersiniosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6JOlaHsd,,,intestine; spleen,invasin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27107739,PubMed,10.1016/j.ijmm.2016.04.002,Int J Med Microbiol. 2016 Apr 19. pii: S1438-4221(16)30040-6,stella.autenrieth@med.uni-tuebingen.de,,D Drechsler-Hake 2016,2016,2 genes,Drechsler-Hake-2016-Mononuclear phagocytes con,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8169,PHI:6253,UniProt,P31489,GenBank,CAA32086,,,6471/76 (serotype O:3),YadA,,,,,,,630,Yersinia enterocolitica,34054,serotype O:8,yersiniosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6JOlaHsd,,,intestine; spleen,adhesion,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27107739,PubMed,10.1016/j.ijmm.2016.04.002,Int J Med Microbiol. 2016 Apr 19. pii: S1438-4221(16)30040-6,stella.autenrieth@med.uni-tuebingen.de,,D Drechsler-Hake 2016,2016,2 genes,Drechsler-Hake-2016-Mononuclear phagocytes con,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8170,PHI:6254,UniProt,S7VVL5,GenBank,EPR59084,,,GT1,myr1,chromosome 3,,,,,,5811,Toxoplasma gondii,508771,type II strain ME49,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,Myc regulation,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26838724,PubMed,10.1128/mBio.02231-15,MBio. 2016 Feb 2;7(1):e02231-15,jboothr@stanford.edu,Parasites deficient inMYR1were found to be severely attenuated in a mouse model of infection,M Franco 2016,2016,1 gene,"Franco-2016-A Novel Secreted Protein, MYR1, Is",BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8171,PHI:6255,UniProt,P0C1S0,GenBank,AAP48794,,,Becker,mgrA,,,,,,,1280,Staphylococcus aureus,,502A,community-acquired infection; nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart,global regulator,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27144398,PubMed,10.1371/journal.ppat.1005604,PLoS Pathog. 2016 May 4;12(5):e1005604,alex-horswill@uiowa.edu,"mgrA mutants are less virulent in a rabbit model of endocarditis, and virulence can be partially restored by deleting the genes for the surface proteins ebh,sraP, and sasG. While mgrA mutants are unable to clump, they are known to have enhanced biofilm capacity.",H A Crosby 2016,2016,1 gene,Crosby-2016-The Staphylococcus aureus Global R,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8172,PHI:6256,UniProt,Q4WW81,GenBank,EAL91145,,,Af293,FleA,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,fucose-specific lectin,,,,increased virulence (hypervirulence),,,,,,,,,,no,(2E)-hexenylalpha-L-fucopyranoside,,,,,,gene disruption; gene complementation,,,RP,27058347,PubMed,10.1371/journal.ppat.1005555,PLoS Pathog. 2016 Apr 8;12(4):e1005555,john.fahy@ucsf.edu,Mice infected with deltafleA conidia had more severe pneumonia and invasive aspergillosis than mice infected with WT conidia/ (2E)-hexenylalpha-L-fucopyranoside is a potent functional inhibitor of FleA.,S C Kerr 2016,2016,1 gene,Kerr-2016-FleA Expression in Aspergillus fumig,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8173,PHI:6257,UniProt,Q5GWL3,GenBank,AAW76908,,,KACC10331,Xoo3654,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain PXO124,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,negative regulator of Xoo virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26839515,PubMed,10.1186/s12953-016-0091-z,Proteome Sci. 2016 Feb 2;14:2,jpchen2001@126.com,"Xoo3654, is likely a negative regulator of Xoo virulence as its overexpression reduced Xoo pathogenicity in our study.",X Chen 2016,2016,1 gene,Chen-2016-Secretome analysis of rice suspensio,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8174,PHI:6258,UniProt,I1RA06,GenBank,CEF72229,,,PH-1,DHS,chromosome 1,,,,,,5518,Fusarium graminearum,,8/151,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spike,deoxyhypusine synthase,,,,increased virulence (hypervirulence),,,,,,increased,,,,no,NaCl; H2O2; calcofluor white; tebuconazole; azoxystrobin,"H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; tebuconazole: CHEBI:81781; azoxystrobin: CHEBI:40909, CAS:131860-33-8",,,,,altered gene expression / gene regulation: overexpression,,,RP,27098988,PubMed,10.1038/srep24698,Sci Rep. 2016 Apr 21;6:24698,ana.lilia.martinez-rocha@uni-hamburg.de,,A L Martinez-Rocha 2016,2016,2 genes,Martinez-Rocha-2016-Posttranslational hypusina,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8175,PHI:6259,UniProt,A0A0E0SEE4,GenBank,CEF84807,,,PH-1,DOHH,chromosome 4,,,,,,5518,Fusarium graminearum,,8/151,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spike,deoxyhypusine hydroxylase,,,,reduced virulence,,yes,yes,yes,,reduced,,,,no,NaCl; H2O2; calcofluor white; tebuconazole; azoxystrobin,"H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; tebuconazole: CHEBI:81781; azoxystrobin: CHEBI:40909, CAS:131860-33-8",,,,,altered gene expression / gene regulation: overexpression,,,RP,27098988,PubMed,10.1038/srep24698,Sci Rep. 2016 Apr 21;6:24698,ana.lilia.martinez-rocha@uni-hamburg.de,,A L Martinez-Rocha 2016,2016,2 genes,Martinez-Rocha-2016-Posttranslational hypusina,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8176,PHI:6258,UniProt,I1RA06,GenBank,CEF72229,,,PH-1,DHS,chromosome 1,,,,,PHI:6259,5518,Fusarium graminearum,,8/151,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spike,deoxyhypusine synthase,,,,unaffected pathogenicity,,no,no,no,,wild type,,,,no,NaCl; H2O2; calcofluor white; tebuconazole; azoxystrobin,"H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; tebuconazole: CHEBI:81781; azoxystrobin: CHEBI:40909, CAS:131860-33-8",,,,,altered gene expression / gene regulation: overexpression,,,RP,27098988,PubMed,10.1038/srep24698,Sci Rep. 2016 Apr 21;6:24698,ana.lilia.martinez-rocha@uni-hamburg.de,,A L Martinez-Rocha 2016,2016,2 genes,Martinez-Rocha-2016-Posttranslational hypusina,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8177,PHI:6259,UniProt,A0A0E0SEE4,GenBank,CEF84807,,,PH-1,DOHH,chromosome 4,,,,,PHI:6258,5518,Fusarium graminearum,,8/151,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spike,deoxyhypusine hydroxylase,,,,unaffected pathogenicity,,no,no,no,,wild type,,,,no,NaCl; H2O2; calcofluor white; tebuconazole; azoxystrobin,"H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; tebuconazole: CHEBI:81781; azoxystrobin: CHEBI:40909, CAS:131860-33-8",,,,,altered gene expression / gene regulation: overexpression,,,RP,27098988,PubMed,10.1038/srep24698,Sci Rep. 2016 Apr 21;6:24698,ana.lilia.martinez-rocha@uni-hamburg.de,,A L Martinez-Rocha 2016,2016,2 genes,Martinez-Rocha-2016-Posttranslational hypusina,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8178,PHI:6260,UniProt,G2XED6,GenBank,EGY18187,,,VdLs.17,Vdpf,chromosome 2,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,transcription factor,,,,reduced virulence,,,,,,reduced,,aberrant,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,26857810,PubMed,10.1111/mpp.12367,Mol Plant Pathol. 2016 Feb 9,donjyaa@swu.edu.cn,,X LUO 2016,2016,1 gene,Luo-2016-The fungal-specific transcription fac,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8179,PHI:6260,UniProt,G2XED6,GenBank,EGY18187,,,VdLs.17,Vdpf,chromosome 2,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,transcription factor,,,,reduced virulence,,,,,,reduced,,aberrant,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,RP,26857810,PubMed,10.1111/mpp.12367,Mol Plant Pathol. 2016 Feb 9,donjyaa@swu.edu.cn,,X LUO 2016,2016,1 gene,Luo-2016-The fungal-specific transcription fac,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8180,PHI:6261,UniProt,G4YQK3,GenBank,EGZ30267,,,P6497,PsAAT3,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,stem,aspartate aminotransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27020161,PubMed,10.1016/j.funbio.2016.01.005,Fungal Biol. 2016 Apr;120(4):620-30,ddou@njau.edu.cn,"Silencing of PsAAT3, an infection-inducible expression gene, reduced P. sojae pathogenicity on soybean plants and affected the growth under N-starving condition, suggesting that PsAAT3 is involved in pathogen pathogenicity and nitrogen utilisation during infection.",R WANG 2016,2016,1 gene,"Wang-2016-PsAAT3, an oomycete-specific asparta",BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8181,PHI:6262,UniProt,W7LS89,GenBank,EWG42063,,,7600,FUG1,,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),,,,kernel,role in pathogenicity and fumonisin biosynthesis,,,,reduced virulence,,,,,,reduced,,,,no,2-benzoxazolinone; hydrogen peroxide,2-benzoxazolinone: CAS:59-49-4; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,27071505,PubMed,10.1111/mpp.12414,Mol Plant Pathol. 2016 Apr 12,bbluhm@uark.edu,Deletion of FUG1 impaired maize kernel colonization and fumonisin biosynthesis.,J B Ridenour 2016,2016,1 gene,Ridenour-2016-The novel fungal-specific gene F,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8182,PHI:6263,UniProt,A0A0D5YID2,GenBank,AKA31704,,,AB5075-UW,adeA,,,,,,PHI:6264,470,Acinetobacter baumannii,,S1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RND MDR efflux system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27094331,PubMed,10.1128/mBio.00430-16,MBio. 2016 Apr 19;7(2). pii: e00430-16,l.j.v.piddock@bham.ac.uk,Deletion ofadeBimpacted only on the ability of strain AYE to form a biofilm on plastic and only on the virulence of strain Singapore 1 for Galleria mellonella.,G E Richmond 2016,2016,2 genes,Richmond-2016-The Acinetobacter baumannii Two-,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8183,PHI:6264,UniProt,A0A0D5YHB7,GenBank,AKA31705,,,AB5075-UW,adeB,,,,,,PHI:6263,470,Acinetobacter baumannii,,S1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RND MDR efflux system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27094331,PubMed,10.1128/mBio.00430-16,MBio. 2016 Apr 19;7(2). pii: e00430-16,l.j.v.piddock@bham.ac.uk,Deletion ofadeBimpacted only on the ability of strain AYE to form a biofilm on plastic and only on the virulence of strain Singapore 1 for Galleria mellonella.,G E Richmond 2016,2016,2 genes,Richmond-2016-The Acinetobacter baumannii Two-,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8184,PHI:6263,UniProt,A0A0D5YID2,GenBank,AKA31704,,,AB5075-UW,adeA,,,,,,PHI:6264,470,Acinetobacter baumannii,509173,AYE,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RND MDR efflux system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27094331,PubMed,10.1128/mBio.00430-16,MBio. 2016 Apr 19;7(2). pii: e00430-16,l.j.v.piddock@bham.ac.uk,Deletion ofadeBimpacted only on the ability of strain AYE to form a biofilm on plastic and only on the virulence of strain Singapore 1 for Galleria mellonella.,G E Richmond 2016,2016,2 genes,Richmond-2016-The Acinetobacter baumannii Two-,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8185,PHI:6264,UniProt,A0A0D5YHB7,GenBank,AKA31705,,,AB5075-UW,adeB,,,,,,PHI:6263,470,Acinetobacter baumannii,509173,AYE,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RND MDR efflux system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27094331,PubMed,10.1128/mBio.00430-16,MBio. 2016 Apr 19;7(2). pii: e00430-16,l.j.v.piddock@bham.ac.uk,Deletion ofadeBimpacted only on the ability of strain AYE to form a biofilm on plastic and only on the virulence of strain Singapore 1 for Galleria mellonella.,G E Richmond 2016,2016,2 genes,Richmond-2016-The Acinetobacter baumannii Two-,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8186,PHI:6265,UniProt,C0NFK7,GenBank,EEH10028,,,G186AR,Eng1,,,,,,,5037,Histoplasma capsulatum,447093,G186A,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"secreted-(1,3)-glucanase",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27094334,PubMed,10.1128/mBio.01388-15,MBio. 2016 Apr 19;7(2). pii: e01388-15,rappleye.1@osu.edu,,A L Garfoot 2016,2016,1 gene,Garfoot-2016-The Eng1 beta-Glucanase Enhances,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8187,PHI:6266,UniProt,M1W4B7,GenBank,CCE29200,,,20.1,cptRNA-ipt,,,,,,,5111,Claviceps purpurea,1111077,20.1,ergot,monocots,4550,Secale cereale (related: rye),cv. Lo37-PxLo55-N,,,floret,tRNA dimethylallyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27074411,PubMed,10.1111/nph.13960,New Phytol. 2016 Apr 13,j_schu51@uni-muenster.de,"Although deltacptRNA-ipt was reduced in virulence, the 'CK-free' double deletion mutant was nearly apathogenic.",J Hinsch 2016,2016,2 genes,Hinsch-2016-Functional characterization of the,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8188,PHI:6267,UniProt,M1WES1,GenBank,CCE30329,,,20.1,cpipt-log,,,,,,,5111,Claviceps purpurea,1111077,20.1,ergot,monocots,4550,Secale cereale (related: rye),cv. Lo37-PxLo55-N,,,floret,cytokinin production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27074411,PubMed,10.1111/nph.13960,New Phytol. 2016 Apr 13,j_schu51@uni-muenster.de,"Although deltacptRNA-ipt was reduced in virulence, the 'CK-free' double deletion mutant was nearly apathogenic.",J Hinsch 2016,2016,2 genes,Hinsch-2016-Functional characterization of the,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8189,PHI:6266,UniProt,M1W4B7,GenBank,CCE29200,,,20.1,cptRNA-ipt,,,,,,PHI:6267,5111,Claviceps purpurea,1111077,20.1,ergot,monocots,4550,Secale cereale (related: rye),cv. Lo37-PxLo55-N,,,floret,tRNA dimethylallyltransferase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27074411,PubMed,10.1111/nph.13960,New Phytol. 2016 Apr 13,j_schu51@uni-muenster.de,"Although deltacptRNA-ipt was reduced in virulence, the 'CK-free' double deletion mutant was nearly apathogenic.",J Hinsch 2016,2016,2 genes,Hinsch-2016-Functional characterization of the,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8190,PHI:6267,UniProt,M1WES1,GenBank,CCE30329,,,20.1,cpipt-log,,,,,,PHI:6266,5111,Claviceps purpurea,1111077,20.1,ergot,monocots,4550,Secale cereale (related: rye),cv. Lo37-PxLo55-N,,,floret,cytokinin production,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27074411,PubMed,10.1111/nph.13960,New Phytol. 2016 Apr 13,j_schu51@uni-muenster.de,"Although deltacptRNA-ipt was reduced in virulence, the 'CK-free' double deletion mutant was nearly apathogenic.",J Hinsch 2016,2016,2 genes,Hinsch-2016-Functional characterization of the,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8191,PHI:6268,UniProt,P00722,GenBank,AAA24053,,,,lacZ,,,,,,,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,urinary bladder,beta-galactosidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27073089,PubMed,10.1128/mBio.00104-16,MBio. 2016 Apr 12;7(2). pii: e00104-16,hultgren@wusm.wustl.edu,,M S Conover 2016,2016,3 genes,Conover-2016-Metabolic Requirements of Escheri,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8192,PHI:6269,UniProt,P0A6T3,GenBank,CAA26172,,,,galK,,,,,,,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,urinary bladder,galactokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27073089,PubMed,10.1128/mBio.00104-16,MBio. 2016 Apr 12;7(2). pii: e00104-16,hultgren@wusm.wustl.edu,,M S Conover 2016,2016,3 genes,Conover-2016-Metabolic Requirements of Escheri,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8193,PHI:6270,UniProt,Q8XBU9,GenBank,AE005239_7,,,EDL933,ybdB,,,,,,,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,urinary bladder,proofreading thioesterase,,,,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,27073089,PubMed,10.1128/mBio.00104-16,MBio. 2016 Apr 12;7(2). pii: e00104-16,hultgren@wusm.wustl.edu,,M S Conover 2016,2016,3 genes,Conover-2016-Metabolic Requirements of Escheri,BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8194,PHI:6271,UniProt,G2X1K9,GenBank,EGY22182,,,VdLs.17,VdThit,chromosome 3,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf; root,thiamine transporter,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,menadione; thiamine,menadione: CHEBI:28869; thiamine: CHEBI:18385,,,,,gene deletion: full; gene complementation,,,RP,27089469,PubMed,10.1094/MPMI-03-16-0057-R,Mol Plant Microbe Interact. 2016 May 16:MPMI03160057R,chenghongmei@caas.cn,,X Qi 2016,2016,1 gene,"Qi-2016-VdThit, a Thiamine Transport Protein",BATCH_059,2016-06-01,MC,,,,,,,,,,,,,
,,Record 8195,PHI:6272,UniProt,I1REC7,GenBank,CEF74237,,,PH-1,FgHSP90,chromosome 1,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,"ubiquitous chaperone, heat shock protein 90",,,,reduced virulence,yes,,,yes,,reduced; aberrant,reduced,reduced,,yes,,,,,,,gene deletion: partial; gene complementation,,,RP,27306495,PubMed,10.1038/srep28154,Sci Rep. 2016 Jun 16;6:28154,lee2443@snu.ac.kr,,D Bui 2016,2016,1 gene,Bui-2016-Heat shock protein 90 is required for,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8196,PHI:6273,UniProt,G8Z3P1,GenBank,ADO30450,,,ECOR63,tcpC,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,urinary bladder; kidney,"Toll/IL-1 receptor-containing (TIR-containing) protein C (TcpC), which impairs TLR signaling",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27214553,PubMed,10.1172/JCI81916,J Clin Invest. 2016 Jul 1;126(7):2425-36,Thomas.Miethke@medma.uniheidelberg.de,"CFT073, express Toll/IL-1 receptor-containing (TIR-containing) protein C (TcpC), which impairs TLR signaling, thereby suppressing innate immunity in the urinary tract and enhancing persistence in the kidneys.",A Waldhuber 2016,2016,1 gene,Waldhuber-2016-Uropathogenic Escherichia coli,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8197,PHI:6274,UniProt,P57665,GenBank,AE004908_2,,,PAO1,Orn,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,oligoribonuclease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27296966,PubMed,10.1016/j.micres.2016.05.002,Microbiol Res. 2016 Jul-Aug;188-189:90-6,zhihuicheng@nankai.edu.cn,,G Chen 2016,2016,1 gene,Chen-2016-Oligoribonuclease is required for th,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8198,PHI:6275,UniProt,Q8P4H6,GenBank,AAM42989,,,ATCC 33913,AvrXccB,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain B186,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27241588,PubMed,10.1111/mpp.12435,Mol Plant Pathol. 2016 May 31,wxs@cau.edu.cn,,L Liu 2016,2016,1 gene,Liu-2016-The type III effector AvrXccB in Xant,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8199,PHI:6276,UniProt,A4VXV9,GenBank,ABP90948,,,05ZYH33,SspA-1,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27270879,PubMed,10.1038/srep27369,Sci Rep. 2016 Jun 8;6:27369,hnyanyanxp@aliyun.com,,S Yin 2016,2016,1 gene,Yin-2016-Subtilisin-like protease-1 secreted t,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8200,PHI:6277,UniProt,B2HST4,GenBank,ECCC5_MYCMM,,,M,esx-5,,,,,,,1781,Mycobacterium marinum,1131442,E11,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,plays a major role in the integrity and stability of the capsule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27280885,PubMed,10.1371/journal.ppat.1005696,PLoS Pathog. 2016 Jun 9;12(6):e1005696,W.Bitter@vumc.nl,,L S Ates 2016,2016,2 genes,Ates-2016-The ESX-5 System of Pathogenic Mycob,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8201,PHI:6278,UniProt,B2HQQ1,GenBank,ACC39221,,,M,ppe10,,,,,,,1781,Mycobacterium marinum,1131442,E11,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,substrate of ESX-5,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27280885,PubMed,10.1371/journal.ppat.1005696,PLoS Pathog. 2016 Jun 9;12(6):e1005696,W.Bitter@vumc.nl,,L S Ates 2016,2016,2 genes,Ates-2016-The ESX-5 System of Pathogenic Mycob,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8202,PHI:6279,,no data found,GenBank,AAT03007,,,F2365,adlp,,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,alkylbase DNA glycosylase,,,,reduced virulence,,,,,,,,reduced,,no,methyl methanesulfonate (MMS); H2O2,H2O2: CHEBI:16240; methyl methanesulfonate (MMS): CHEBI:25255,,,,,gene deletion: full; gene complementation,,,RP,27316964,PubMed,10.1128/AEM.00719-16,Appl Environ Microbiol. 2016 Jun 17,cw57@msstate.edu,,T Zhang 2016,2016,1 gene,"Zhang-2016-The DNA glycosylase, Adlp Affects F",BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8203,PHI:6280,UniProt,J4W8U0,GenBank,EJP66630,,,ARSEF 2860,bmiro,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitochondrial Rho GTPase,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,27241960,PubMed,10.1016/j.fgb.2016.05.005,Fungal Genet Biol. 2016 Aug;93:1-9,mgfeng@zju.edu.cn,,Y Guan 2016,2016,1 gene,Guan-2016-Miro GTPase controls mitochondrial b,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8204,PHI:6281,UniProt,H2BJK0,GenBank,AEV46773,,,MNZ11,PspK,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,34839,Chinchilla lanigera (related: long-tailed chinchilla),,,,tympanum,pneumococcal surface protein K,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27242973,PubMed,10.3389/fcimb.2016.00055,Front Cell Infect Microbiol. 2016 May 18;6:55,lmcdaniel@umc.edu,,L E Keller 2016,2016,4 genes,Keller-2016-Surface Proteins and Pneumolysin o,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8205,PHI:6282,UniProt,Q04IN8,GenBank,CAA36714,,,"NCTC 7466, serotype II",Ply,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,34839,Chinchilla lanigera (related: long-tailed chinchilla),,,,tympanum,pneumolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27242973,PubMed,10.3389/fcimb.2016.00055,Front Cell Infect Microbiol. 2016 May 18;6:55,lmcdaniel@umc.edu,,L E Keller 2016,2016,4 genes,Keller-2016-Surface Proteins and Pneumolysin o,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8206,PHI:6283,UniProt,A0A0T7Z0W5,GenBank,CIP80280,,,N,PspA,,,,,,PHI:6284; PHI:6282,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,34839,Chinchilla lanigera (related: long-tailed chinchilla),,,,tympanum,pneumococcal surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27242973,PubMed,10.3389/fcimb.2016.00055,Front Cell Infect Microbiol. 2016 May 18;6:55,lmcdaniel@umc.edu,,L E Keller 2016,2016,4 genes,Keller-2016-Surface Proteins and Pneumolysin o,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8207,PHI:6284,UniProt,Q9FDQ1,GenBank,AF154043_1,,,srf15,PspC,,,,,,PHI:6283; PHI:6282,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,34839,Chinchilla lanigera (related: long-tailed chinchilla),,,,tympanum,pneumococcal surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27242973,PubMed,10.3389/fcimb.2016.00055,Front Cell Infect Microbiol. 2016 May 18;6:55,lmcdaniel@umc.edu,,L E Keller 2016,2016,4 genes,Keller-2016-Surface Proteins and Pneumolysin o,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8208,PHI:6282,UniProt,Q04IN8,GenBank,CAA36714,,,"NCTC 7466, serotype II",Ply,,,,,,PHI:6283; PHI:6284,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,34839,Chinchilla lanigera (related: long-tailed chinchilla),,,,tympanum,pneumolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27242973,PubMed,10.3389/fcimb.2016.00055,Front Cell Infect Microbiol. 2016 May 18;6:55,lmcdaniel@umc.edu,,L E Keller 2016,2016,4 genes,Keller-2016-Surface Proteins and Pneumolysin o,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8209,PHI:6285,UniProt,Q8NID8,GenBank,AGD98923,,,ELH,Avr2,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,Rcr3 UniProt: Q8S333,,,functional test in host: transient expression,,,RP,19171904,PubMed,10.1073/pnas.0809201106,Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1654-9,sophien.kamoun@tsl.ac.uk,"Avr2, EPIC1, and EPIC2B secreted by two unrelated pathogens of tomato target the same defense protease Rcr3",J Song 2009,2009,3 genes,Song-2009-Apoplastic effectors secreted by two,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8210,PHI:6286,UniProt,D0NBV1,GenBank,EEY55256,,,T30-4,EPIC1,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,Rcr3 UniProt: Q8S333,,,functional test in host: transient expression,,,RP,19171904,PubMed,10.1073/pnas.0809201106,Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1654-9,sophien.kamoun@tsl.ac.uk,"Avr2, EPIC1, and EPIC2B secreted by two unrelated pathogens of tomato target the same defense protease Rcr3",J Song 2009,2009,3 genes,Song-2009-Apoplastic effectors secreted by two,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8211,PHI:6287,UniProt,D0NBV3,GenBank,EEY55258,,,T30-4,EPIC2B,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,Rcr3 UniProt: Q8S333,,,functional test in host: transient expression,,,RP,19171904,PubMed,10.1073/pnas.0809201106,Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1654-9,sophien.kamoun@tsl.ac.uk,"Avr2, EPIC1, and EPIC2B secreted by two unrelated pathogens of tomato target the same defense protease Rcr3",J Song 2009,2009,3 genes,Song-2009-Apoplastic effectors secreted by two,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8212,PHI:6288,UniProt,Q1AC96,GenBank,ABC60070,,,93-146,EseG,,,,,,,67780,Edwardsiella ictaluri,,,enteric septicemia (catfish),bony fishes,7998,Ictalurus punctatus (related: Channel catfish),,,,ovary,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303737,PubMed,10.1128/mSphere.00039-16,mSphere. 2016 May 11;1(3). pii: e00039-16,thune@vetmed.lsu.edu,,L P Dubytska 2016,2016,9 genes,Dubytska-2016-Identification and Characterizat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8213,PHI:6289,UniProt,Q9KI30,GenBank,AF244083_1,,,,EseH,,,,,,,67780,Edwardsiella ictaluri,,,enteric septicemia (catfish),bony fishes,7998,Ictalurus punctatus (related: Channel catfish),,,,ovary,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303737,PubMed,10.1128/mSphere.00039-16,mSphere. 2016 May 11;1(3). pii: e00039-16,thune@vetmed.lsu.edu,,L P Dubytska 2016,2016,9 genes,Dubytska-2016-Identification and Characterizat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8214,PHI:6290,UniProt,M1L5E8,GenBank,AGF34188,,,2s,EseI,,,,,,,67780,Edwardsiella ictaluri,,,enteric septicemia (catfish),bony fishes,7998,Ictalurus punctatus (related: Channel catfish),,,,ovary,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303737,PubMed,10.1128/mSphere.00039-16,mSphere. 2016 May 11;1(3). pii: e00039-16,thune@vetmed.lsu.edu,,L P Dubytska 2016,2016,9 genes,Dubytska-2016-Identification and Characterizat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8215,PHI:6291,UniProt,C5B8F6,GenBank,ACR69526,,,93-146,EseJ,,,,,,,67780,Edwardsiella ictaluri,,,enteric septicemia (catfish),bony fishes,7998,Ictalurus punctatus (related: Channel catfish),,,,ovary,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303737,PubMed,10.1128/mSphere.00039-16,mSphere. 2016 May 11;1(3). pii: e00039-16,thune@vetmed.lsu.edu,,L P Dubytska 2016,2016,9 genes,Dubytska-2016-Identification and Characterizat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8216,PHI:6292,,no data found,,,,,,EseK,,,,,,,67780,Edwardsiella ictaluri,,,enteric septicemia (catfish),bony fishes,7998,Ictalurus punctatus (related: Channel catfish),,,,ovary,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303737,PubMed,10.1128/mSphere.00039-16,mSphere. 2016 May 11;1(3). pii: e00039-16,thune@vetmed.lsu.edu,,L P Dubytska 2016,2016,9 genes,Dubytska-2016-Identification and Characterizat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8217,PHI:6293,UniProt,C5BD28,GenBank,ACR68523,,,93-146,EseL,,,,,,,67780,Edwardsiella ictaluri,,,enteric septicemia (catfish),bony fishes,7998,Ictalurus punctatus (related: Channel catfish),,,,ovary,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303737,PubMed,10.1128/mSphere.00039-16,mSphere. 2016 May 11;1(3). pii: e00039-16,thune@vetmed.lsu.edu,,L P Dubytska 2016,2016,9 genes,Dubytska-2016-Identification and Characterizat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8218,PHI:6294,UniProt,C5BD30,GenBank,ACR68525,,,93-146,EseM,,,,,,,67780,Edwardsiella ictaluri,,,enteric septicemia (catfish),bony fishes,7998,Ictalurus punctatus (related: Channel catfish),,,,ovary,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303737,PubMed,10.1128/mSphere.00039-16,mSphere. 2016 May 11;1(3). pii: e00039-16,thune@vetmed.lsu.edu,,L P Dubytska 2016,2016,9 genes,Dubytska-2016-Identification and Characterizat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8219,PHI:6295,UniProt,C5BA03,GenBank,ACR69124,,,93-146,EseN,,,,,,,67780,Edwardsiella ictaluri,,,enteric septicemia (catfish),bony fishes,7998,Ictalurus punctatus (related: Channel catfish),,,,ovary,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303737,PubMed,10.1128/mSphere.00039-16,mSphere. 2016 May 11;1(3). pii: e00039-16,thune@vetmed.lsu.edu,,L P Dubytska 2016,2016,9 genes,Dubytska-2016-Identification and Characterizat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8220,PHI:6296,UniProt,C5B8P0,GenBank,ACR69900,,,93-146,EseO,,,,,,,67780,Edwardsiella ictaluri,,,enteric septicemia (catfish),bony fishes,7998,Ictalurus punctatus (related: Channel catfish),,,,ovary,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303737,PubMed,10.1128/mSphere.00039-16,mSphere. 2016 May 11;1(3). pii: e00039-16,thune@vetmed.lsu.edu,,L P Dubytska 2016,2016,9 genes,Dubytska-2016-Identification and Characterizat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8221,PHI:6297,UniProt,Q5K6X5,GenBank,AAW47144,,,JEC21,CDC50,,MAT cdc50 ::NEO,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; brain,lipid flippase subunit,,,,reduced virulence,,,,,,,,,,no,fluconazole; caspofungin,"caspofungin: CHEBI:474180; fluconazole: CHEBI:46081, CAS:86386-73-4",,,,,gene deletion: full; gene complementation,,,RP,27165800,PubMed,10.1128/mBio.00478-16,MBio. 2016 May 10;7(3). pii: e00478-16,xuech@njms.rutgers.edu,CDC50 is essential for fungal resistance to macrophage killing and for virulence in a murine model of cryptococcosis.,W Huang 2016,2016,1 gene,Huang-2016-Lipid Flippase Subunit Cdc50 Mediat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8222,PHI:6298,UniProt,Q8Y1E6,GenBank,CAD14274,,,GMI1000,nucA,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,root,extracellular DNase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27336156,PubMed,10.1371/journal.ppat.1005686,PLoS Pathog. 2016 Jun 23;12(6):e1005686,callen@wisc.edu,Single deltanucA and deltanucBmutants and thedeltanucA/Bdouble mutant all had reduced virulence on wilt-susceptible tomato plants in a naturalistic soil-soak inoculation assay.,T M Tran 2016,2016,2 genes,Tran-2016-Escaping Underground Nets_ Extracell,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8223,PHI:6299,UniProt,Q8XWM2,GenBank,CAD16159,,,GMI1000,nucB,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,root,extracellular DNase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27336156,PubMed,10.1371/journal.ppat.1005686,PLoS Pathog. 2016 Jun 23;12(6):e1005686,callen@wisc.edu,Single deltanucA and deltanucBmutants and thedeltanucA/Bdouble mutant all had reduced virulence on wilt-susceptible tomato plants in a naturalistic soil-soak inoculation assay.,T M Tran 2016,2016,2 genes,Tran-2016-Escaping Underground Nets_ Extracell,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8224,PHI:6298,UniProt,Q8Y1E6,GenBank,CAD14274,,,GMI1000,nucA,,,,,,PHI:6299,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,root,extracellular DNase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27336156,PubMed,10.1371/journal.ppat.1005686,PLoS Pathog. 2016 Jun 23;12(6):e1005686,callen@wisc.edu,Single deltanucA and deltanucBmutants and thedeltanucA/Bdouble mutant all had reduced virulence on wilt-susceptible tomato plants in a naturalistic soil-soak inoculation assay.,T M Tran 2016,2016,2 genes,Tran-2016-Escaping Underground Nets_ Extracell,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8225,PHI:6299,UniProt,Q8XWM2,GenBank,CAD16159,,,GMI1000,nucB,,,,,,PHI:6298,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,root,extracellular DNase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27336156,PubMed,10.1371/journal.ppat.1005686,PLoS Pathog. 2016 Jun 23;12(6):e1005686,callen@wisc.edu,Single deltanucA and deltanucBmutants and thedeltanucA/Bdouble mutant all had reduced virulence on wilt-susceptible tomato plants in a naturalistic soil-soak inoculation assay.,T M Tran 2016,2016,2 genes,Tran-2016-Escaping Underground Nets_ Extracell,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8226,PHI:6300,UniProt,I1RE83,GenBank,CEF74175,,,PH-1,FgPDK1,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Yangmai 49,,,spikelet,pyruvate dehydrogenase kinase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,NaCl; KCl; caffeine; congo red; SDS,NaCl: CHEBI:26710; KCl: CHEBI:32588; caffeine: CHEBI:27732; congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,27341107,PubMed,10.1371/journal.pone.0158077,PLoS One. 2016 Jun 24;11(6):e0158077,shizhiqi@jaas.ac.cn,"The deletion of FgPDK1 also prohibited the production of deoxynivalenol (DON) and pathogenicity ofF.graminearum, which may resulted from the decrease in the expression of Tri6.",T Gao 216,2016,1 gene,Gao-2016-Fusarium graminearum pyruvate dehydro,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8227,PHI:6300,UniProt,I1RE83,GenBank,CEF74175,,,PH-1,FgPDK1,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,pyruvate dehydrogenase kinase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,NaCl; KCl; caffeine; congo red; SDS,NaCl: CHEBI:26710; KCl: CHEBI:32588; caffeine: CHEBI:27732; congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,27341107,PubMed,10.1371/journal.pone.0158077,PLoS One. 2016 Jun 24;11(6):e0158077,shizhiqi@jaas.ac.cn,"The deletion of FgPDK1 also prohibited the production of deoxynivalenol (DON) and pathogenicity ofF.graminearum, which may resulted from the decrease in the expression of Tri6.",T Gao 216,2016,1 gene,Gao-2016-Fusarium graminearum pyruvate dehydro,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8228,PHI:6301,UniProt,D0MZL5,GenBank,EEY65678,,,T30-4,PITG_03192,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,RxLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,24130484,PubMed,10.1371/journal.ppat.1003670,PLoS Pathog. 2013;9(10):e1003670,Paul.Birch@dundee.ac.uk,"Silencing of NTP1 or NTP2 in the model host plantNicotiana benthamianaincreases susceptibility to P. infestans, whereas silencing of Pi03192 in P. Infestans reduces pathogenicity.",H McLellan 2013,2013,3 genes,McLellan-2013-An RxLR effector from Phytophtho,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8229,PHI:6301,UniProt,D0MZL5,GenBank,EEY65678,,,T30-4,PITG_03192,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,RxLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,24130484,PubMed,10.1371/journal.ppat.1003670,PLoS Pathog. 2013;9(10):e1003670,Paul.Birch@dundee.ac.uk,"Silencing of NTP1 or NTP2 in the model host plantNicotiana benthamianaincreases susceptibility to P. infestans, whereas silencing of Pi03192 in P. Infestans reduces pathogenicity.",H McLellan 2013,2013,3 genes,McLellan-2013-An RxLR effector from Phytophtho,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8230,PHI:6304,,no data found,,Pst_28188,,,,PsRas1,,,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,Ras GTPase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27206348,PubMed,10.1111/1462-2920.13379,Environ Microbiol. 2016 May 21,kangzs@nwsuaf.edu.cn,"Silencing of PsRas1 or PsRas2 indicates that PsRas2 but not PsRas1 contributes significantly to rust pathogenicity. However, overexpression of PsRas1, but not PsRas2, promotes cell death in yeast and plants.",Y Cheng 2016,2016,2 genes,Cheng-2016-Two distinct Ras genes from Puccini,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8231,PHI:6305,,no data found,,Pst_11191,,,,PsRas2,,,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,Ras GTPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27206348,PubMed,10.1111/1462-2920.13379,Environ Microbiol. 2016 May 21,kangzs@nwsuaf.edu.cn,"Silencing of PsRas1 or PsRas2 indicates that PsRas2 but not PsRas1 contributes significantly to rust pathogenicity. However, overexpression of PsRas1, but not PsRas2, promotes cell death in yeast and plants.",Y Cheng 2016,2016,2 genes,Cheng-2016-Two distinct Ras genes from Puccini,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8232,PHI:6304,,no data found,,Pst_28188,,,,PsRas1,,,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,Ras GTPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,27206348,PubMed,10.1111/1462-2920.13379,Environ Microbiol. 2016 May 21,kangzs@nwsuaf.edu.cn,"Silencing of PsRas1 or PsRas2 indicates that PsRas2 but not PsRas1 contributes significantly to rust pathogenicity. However, overexpression of PsRas1, but not PsRas2, promotes cell death in yeast and plants.",Y Cheng 2016,2016,2 genes,Cheng-2016-Two distinct Ras genes from Puccini,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8233,PHI:6305,,no data found,,Pst_11191,,,,PsRas2,,,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,Ras GTPase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,27206348,PubMed,10.1111/1462-2920.13379,Environ Microbiol. 2016 May 21,kangzs@nwsuaf.edu.cn,"Silencing of PsRas1 or PsRas2 indicates that PsRas2 but not PsRas1 contributes significantly to rust pathogenicity. However, overexpression of PsRas1, but not PsRas2, promotes cell death in yeast and plants.",Y Cheng 2016,2016,2 genes,Cheng-2016-Two distinct Ras genes from Puccini,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8234,PHI:6306,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,PopP2,,none (wild-type),,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Niederzenz-1,RRS1-R resistant (wild-type),UniProt: P0DKH5,root (leaf),type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,resistance,,other evidence: wild-type inoculation,,,RP; AC,12788974,PubMed,10.1073/pnas.1230660100,Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):8024-9. Epub 2003 Jun 3,Ldesland@mpiz-koeln.mpg.de,"PopP2, a R. Solanacearum type III effector, which belongs to the YopJ AvrRxv proteinfamily, is the avirulence protein recognized by RRS1-R.",L Deslandes 2003,2003,1 gene,Deslandes-2003-Physical interaction between RR,BATCH_060/AC First host target curation,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8235,PHI:6306,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,PopP2,,deletion of 3 prime terminal half of gene,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Niederzenz-1,RRS1-R resistant (wild-type),UniProt: P0DKH5,root (leaf),type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptible,,gene deletion: partial; gene complementation,,,RP; AC,12788974,PubMed,10.1073/pnas.1230660100,Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):8024-9. Epub 2003 Jun 3,Ldesland@mpiz-koeln.mpg.de,"PopP2, a R. Solanacearum type III effector, which belongs to the YopJ AvrRxv proteinfamily, is the avirulence protein recognized by RRS1-R.",L Deslandes 2003,2003,1 gene,Deslandes-2003-Physical interaction between RR,BATCH_060/AC First host target curation,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8236,PHI:6306,UniProt,Q8Y125,GenBank,CAD14570; Ensembl: RSc0868,,,GMI1000,PopP2,,Nub::PopP2 (yeast split-ubiquitin two-hybrid system),,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: yeast),ecotype Niederzenz-1,,,root (leaf),type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,RRS1-R::Cub-URA3 (yeast split-ubiquitin two-hybrid system),UniProt: P0DKH5; Ensembl: AT5G45260,positive physical interaction,,other evidence: yeast split-ubiquitin two-hybrid system,,,RP; AC,12788974,PubMed,10.1073/pnas.1230660100,Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):8024-9. Epub 2003 Jun 3,Ldesland@mpiz-koeln.mpg.de,PopP2 also physically interacted with the RRS1-S suceptible Arabidopsis allele in the yeast split-ubiquitin two-hybrid system.,L Deslandes 2003,2003,1 gene,Deslandes-2003-Physical interaction between RR,BATCH_060/AC First host target curation,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8237,PHI:6307,UniProt,A0A169T708,GenBank,BAU98376,,,,AVR1,,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain Chiba-5,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ponderosa,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27190160,PubMed,10.1093/femsle/fnw132,FEMS Microbiol Lett. 2016 Jul;363(14). pii: fnw132,arie@cc.tuat.ac.jp,,T Kashiwa 2016,2016,1 gene,Kashiwa-2016-A new biotype of Fusarium oxyspor,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8238,PHI:6308,UniProt,A8Z0F5,GenBank,ABX28234,,,USA300_TCH1516,glcA,,,,,,PHI:6309; PHI:6310; PHI:6311,1280,Staphylococcus aureus,,COL,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,glucose uptake protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27329749,PubMed,10.1128/mBio.00296-16,MBio. 2016 Jun 21;7(3). pii: e00296-16,anthony.richardson@pitt.edu,Targeted inactivation of sugar transporters reduced glucose uptake and attenuated S. Aureus in a murine model of skin and soft tissue infections. These 4 genes have redundant functions.,N P Vitko 2016,2016,4 genes,Vitko-2016-Expanded Glucose Import Capability,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8239,PHI:6309,UniProt,A8Z3D6,GenBank,ABX30516,,,USA300_TCH1516,glcB,,,,,,PHI:6308; PHI:6310; PHI:6311,1280,Staphylococcus aureus,,COL,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,glucose uptake protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27329749,PubMed,10.1128/mBio.00296-16,MBio. 2016 Jun 21;7(3). pii: e00296-16,anthony.richardson@pitt.edu,Targeted inactivation of sugar transporters reduced glucose uptake and attenuated S. Aureus in a murine model of skin and soft tissue infections. These 4 genes have redundant functions.,N P Vitko 2016,2016,4 genes,Vitko-2016-Expanded Glucose Import Capability,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8240,PHI:6310,,no data found,,,,,,glcC,,,,,,PHI:6308; PHI:6309; PHI:6311,1280,Staphylococcus aureus,,COL,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,glucose uptake protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27329749,PubMed,10.1128/mBio.00296-16,MBio. 2016 Jun 21;7(3). pii: e00296-16,anthony.richardson@pitt.edu,Targeted inactivation of sugar transporters reduced glucose uptake and attenuated S. Aureus in a murine model of skin and soft tissue infections. These 4 genes have redundant functions.,N P Vitko 2016,2016,4 genes,Vitko-2016-Expanded Glucose Import Capability,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8241,PHI:6311,UniProt,P60943,GenBank,BAB58418,,,Mu50,glcU,,,,,,PHI:6308; PHI:6309; PHI:6310,1280,Staphylococcus aureus,,COL,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,glucose uptake protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27329749,PubMed,10.1128/mBio.00296-16,MBio. 2016 Jun 21;7(3). pii: e00296-16,anthony.richardson@pitt.edu,Targeted inactivation of sugar transporters reduced glucose uptake and attenuated S. Aureus in a murine model of skin and soft tissue infections. These 4 genes have redundant functions.,N P Vitko 2016,2016,4 genes,Vitko-2016-Expanded Glucose Import Capability,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8242,PHI:6311,UniProt,P60943,GenBank,BAB58418,,,Mu50,glcU,,,,,,,1280,Staphylococcus aureus,,COL,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,glucose uptake protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27329749,PubMed,10.1128/mBio.00296-16,MBio. 2016 Jun 21;7(3). pii: e00296-16,anthony.richardson@pitt.edu,Targeted inactivation of sugar transporters reduced glucose uptake and attenuated S. Aureus in a murine model of skin and soft tissue infections. These 4 genes have redundant functions.,N P Vitko 2016,2016,4 genes,Vitko-2016-Expanded Glucose Import Capability,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8243,PHI:6312,UniProt,D8N152,GenBank,CBJ35355,,,PSI07,awr5,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III effector,,,TOR signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27257085,PubMed,10.1038/srep27058,Sci Rep. 2016 Jun 3;6:27058,nuria.sanchez-coll@cragenomica.es,T3E caused a decrease in TOR-regulated plant nitrate reductase activity and normal levels of TOR and the Cdc55 homologues in plants are required for R. Solanacearum virulence.,C Popa 2016,2016,1 gene,Popa-2016-The effector AWR5 from the plant pat,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8244,PHI:6313,UniProt,Q48K33,GenBank,AAZ35608,,,1448A,kdpD,,,,,,,317,Pseudomonas syringae,,MB03,bacterial speck,nematodes,6239,Caenorhabditis elegans (related: roundworm),L4 larval stage,,,gut,potassium homeostasis and virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303387,PubMed,10.3389/fmicb.2016.00805,Front Microbiol. 2016 May 30;7:805,lilin@mail.hzau.edu.cn,,M Ali 2016,2016,2 genes,Ali-2016-The Pathogenicity of Pseudomonas syri,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8245,PHI:6314,UniProt,Q48K32,GenBank,AAZ36556,,,1448A,kdpE,,,,,,,317,Pseudomonas syringae,,MB03,bacterial speck,nematodes,6239,Caenorhabditis elegans (related: roundworm),L4 larval stage,,,gut,potassium homeostasis and virulence,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27303387,PubMed,10.3389/fmicb.2016.00805,Front Microbiol. 2016 May 30;7:805,lilin@mail.hzau.edu.cn,,M Ali 2016,2016,2 genes,Ali-2016-The Pathogenicity of Pseudomonas syri,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8246,PHI:6315,UniProt,Q9HGU2,GenBank,AF286533_1,,,,fmk1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8247,PHI:6316,UniProt,W9MGC4,GenBank,EWZ90408,,,MN25,mpk1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8248,PHI:6317,UniProt,A0A0D2XQS0,GenBank,KNB04056,,,4287,Hog1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8249,PHI:6315,UniProt,Q9HGU2,GenBank,AF286533_1,,,,fmk1,,,,,,PHI:6316,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8250,PHI:6316,UniProt,W9MGC4,GenBank,EWZ90408,,,MN25,mpk1,,,,,,PHI:63165,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8251,PHI:6316,UniProt,W9MGC4,GenBank,EWZ90408,,,MN25,mpk1,,,,,,PHI:6317,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8252,PHI:6317,UniProt,A0A0D2XQS0,GenBank,KNB04056,,,4287,Hog1,,,,,,PHI:6316,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8253,PHI:6315,UniProt,Q9HGU2,GenBank,AF286533_1,,,,fmk1,,,,,,PHI:6317,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8254,PHI:6317,UniProt,A0A0D2XQS0,GenBank,KNB04056,,,4287,Hog1,,,,,,PHI:6315,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8255,PHI:6315,UniProt,Q9HGU2,GenBank,AF286533_1,,,,fmk1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8256,PHI:6316,UniProt,W9MGC4,GenBank,EWZ90408,,,MN25,mpk1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8257,PHI:6317,UniProt,A0A0D2XQS0,GenBank,KNB04056,,,4287,Hog1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8258,PHI:6315,UniProt,Q9HGU2,GenBank,AF286533_1,,,,fmk1,,,,,,PHI:6316,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8259,PHI:6316,UniProt,W9MGC4,GenBank,EWZ90408,,,MN25,mpk1,,,,,,PHI:63165,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8260,PHI:6316,UniProt,W9MGC4,GenBank,EWZ90408,,,MN25,mpk1,,,,,,PHI:6317,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8261,PHI:6317,UniProt,A0A0D2XQS0,GenBank,KNB04056,,,4287,Hog1,,,,,,PHI:6316,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8262,PHI:6315,UniProt,Q9HGU2,GenBank,AF286533_1,,,,fmk1,,,,,,PHI:6317,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8263,PHI:6317,UniProt,A0A0D2XQS0,GenBank,KNB04056,,,4287,Hog1,,,,,,PHI:6315,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MAP kinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,menadione; fludioxonil; iprodione,"fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869",,,,,gene deletion: full; gene complementation,,,RP,27301316,PubMed,10.1111/mpp.12446,Mol Plant Pathol. 2016 Jun 15,ge3tutud@uco.es,,D S Luque 2016,2016,3 genes,Luque-2016-Three Fusarium oxysporum MAPKs have,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8264,PHI:6318,UniProt,D0ZV89,GenBank,ACY87894,,,14028S,PhoQ,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,pH sensing,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27282333,PubMed,10.1111/mmi.13439,Mol Microbiol. 2016 Jun 10,,"Amino acid substitutions in PhoQ's cytoplasmic domain hindered activation by acidic pH and attenuated virulence in mice, but did not abolish activation by low Mg2+ or the antimicrobial peptide C18G. Conversely, removal of PhoQ's extracytoplasmic domains prevented the response to the latter PhoQ-activating signals but not to acidic pH.",J Choi 2016,2016,1 gene,Choi-2016-Acidic pH sensing in the bacterial c,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8265,PHI:6319,UniProt,Q8DPC2,GenBank,AAL00050,,,R6,potA,,,,,,PHI:6320; PHI:6321; PHI:6322,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,ABC transporter ATP-binding protein-spermidine/putrescine transport,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27247105,PubMed,10.1038/srep26964,Sci Rep. 2016 Jun 1;6:26964,bnanduri@cvm.msstate.edu,The wild type persists in mouse lung 24 h post infection while the mutant strain is cleared by host defense mechanisms.,A N Rai 2016,2016,4 genes,Rai-2016-Polyamine transporter in Streptococcu,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8266,PHI:6320,UniProt,A0A0B7LYL4,GenBank,CEV82963,,,SMRU1010,potB,,,,,,PHI:6319; PHI:6321; PHI:6322,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,ABC transporter ATP-binding protein-spermidine/putrescine transport,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27247105,PubMed,10.1038/srep26964,Sci Rep. 2016 Jun 1;6:26964,bnanduri@cvm.msstate.edu,The wild type persists in mouse lung 24 h post infection while the mutant strain is cleared by host defense mechanisms.,A N Rai 2016,2016,4 genes,Rai-2016-Polyamine transporter in Streptococcu,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8267,PHI:6321,UniProt,Q8DPC4,GenBank,AAL00048,,,R6,potC,,,,,,PHI:6319; PHI:6320; PHI:6322,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,ABC transporter ATP-binding protein-spermidine/putrescine transport,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27247105,PubMed,10.1038/srep26964,Sci Rep. 2016 Jun 1;6:26964,bnanduri@cvm.msstate.edu,The wild type persists in mouse lung 24 h post infection while the mutant strain is cleared by host defense mechanisms.,A N Rai 2016,2016,4 genes,Rai-2016-Polyamine transporter in Streptococcu,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8268,PHI:6322,UniProt,A0A0B7MDN1,GenBank,CEV82959,,,SMRU1010,potD,,,,,,PHI:6319; PHI:6320; PHI:6321,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,ABC transporter ATP-binding protein-spermidine/putrescine transport,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27247105,PubMed,10.1038/srep26964,Sci Rep. 2016 Jun 1;6:26964,bnanduri@cvm.msstate.edu,The wild type persists in mouse lung 24 h post infection while the mutant strain is cleared by host defense mechanisms.,A N Rai 2016,2016,4 genes,Rai-2016-Polyamine transporter in Streptococcu,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8269,PHI:6323,UniProt,D0N0I4,GenBank,EEY67147,,,T30-4,AVRblb2,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,RXLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,22143776,PubMed,10.1073/pnas.1112708109,Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20832-7,sophien.kamoun@tsl.ac.uk,AVRblb2 significantly enhances susceptibility of host plants to P. infestansby targeting the host papain-like cysteine protease C14 and specifically preventing its secretion into the apoplast.,T O Bozkurt 2011,2011,1 gene,Bozkurt-2011-Phytophthora infestans effector A,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8270,PHI:6324,UniProt,Q53763,GenBank,CAA83065,,,RN4220,StpC,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,birds,9031,Gallus gallus (related: chicken),,,,embryo,cysteine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,27242969,PubMed,10.3389/fcimb.2016.00051,Front Cell Infect Microbiol. 2016 May 6;6:51,benedykt.wladyka@uj.edu.pl,Staphopain C alone does not affect staphylococcal virulence in a chicken embryo model.,E Bonar 2016,2016,1 gene,Bonar-2016-Identification of Secreted Exoprote,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8271,PHI:6326,UniProt,Q5AC06,GenBank,EAL00211,,,SC5314,SAC6,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,fimbrin,,,,reduced virulence,,,,,,,,aberrant,aberrant,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,RP,27275845,PubMed,10.1016/j.bbamcr.2016.06.002,Biochim Biophys Acta. 2016 Sep;1863(9):2255-66,nklimingchun@163.com,"Deletion of SAC6 led to increased tolerance to oxidative stress, while its overexpression caused hyper-susceptibility to this stress. Loss of Sac6 enhanced hyphal maintenance, and its overexpression caused a defect in hyphal development, which was attributed to abnormal expression of morphogenesis-related genes. In addition, Sac6 was involved in regulation of secretion of lytic enzymes and virulence of C. albicans.",B Zhang 2016,2016,1 gene,Zhang-2016-The Candida albicans fimbrin Sac6 r,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8272,PHI:6326,UniProt,Q5AC06,GenBank,EAL00211,,,SC5314,SAC6,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,fimbrin,,,,reduced virulence,,,,,,,,aberrant,aberrant,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,RP,27275845,PubMed,10.1016/j.bbamcr.2016.06.002,Biochim Biophys Acta. 2016 Sep;1863(9):2255-66,nklimingchun@163.com,"Deletion of SAC6 led to increased tolerance to oxidative stress, while its overexpression caused hyper-susceptibility to this stress. Loss of Sac6 enhanced hyphal maintenance, and its overexpression caused a defect in hyphal development, which was attributed to abnormal expression of morphogenesis-related genes. In addition, Sac6 was involved in regulation of secretion of lytic enzymes and virulence of C. albicans.",B Zhang 2016,2016,1 gene,Zhang-2016-The Candida albicans fimbrin Sac6 r,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8273,PHI:6327,UniProt,L7IT41,GenBank,ELQ59117,,,P131,MoMKK1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,MAP kinase kinase,,,MAP kinase pathway,reduced virulence,,,,,,reduced,,aberrant,,no,NaCl; KCl; sorbitol,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:17924,,,,,gene deletion: full; gene complementation,,,RP,27193947,PubMed,10.1111/mpp.12317,Mol Plant Pathol. 2016 Jun;17(5):654-68,zhgzhang@njau.edu.cn,"Disruption of MoMKK1 resulted in less aerial hyphal formation, defective asexual development and attenuated pathogenicity.",Z YIN 2016,2016,1 gene,Yin-2016-Phosphodiesterase MoPdeH targets MoMc,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8274,PHI:6328,UniProt,D2TRM0,GenBank,CBG90279,,,ICC168,QseC,,,,,,,67825,Citrobacter rodentium,,,,rodents,10090,Mus musculus (related: house mouse),B6;129S7-Dbh<tm1Rpa>/Rpa,,,colon; gut,adrenergic sensors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27273829,PubMed,10.1128/mBio.00826-16,MBio. 2016 Jun 7;7(3). pii: e00826-16,vanessa.sperandio@utsouthwestern.edu,,C G Moreira 2016,2016,2 genes,Moreira-2016-Bacterial Adrenergic Sensors Regu,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8275,PHI:6329,,no data found,,,,,,QseE,,,,,,,67825,Citrobacter rodentium,,,,rodents,10090,Mus musculus (related: house mouse),B6;129S7-Dbh<tm1Rpa>/Rpa,,,colon; gut,adrenergic sensors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27273829,PubMed,10.1128/mBio.00826-16,MBio. 2016 Jun 7;7(3). pii: e00826-16,vanessa.sperandio@utsouthwestern.edu,,C G Moreira 2016,2016,2 genes,Moreira-2016-Bacterial Adrenergic Sensors Regu,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8276,PHI:6328,UniProt,D2TRM0,GenBank,CBG90279,,,ICC168,QseC,,,,,,,67825,Citrobacter rodentium,,,,rodents,10090,Mus musculus (related: house mouse),129S7/SvEvBrd-Hprt<+>,,,colon; gut,adrenergic sensors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27273829,PubMed,10.1128/mBio.00826-16,MBio. 2016 Jun 7;7(3). pii: e00826-16,vanessa.sperandio@utsouthwestern.edu,,C G Moreira 2016,2016,2 genes,Moreira-2016-Bacterial Adrenergic Sensors Regu,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8277,PHI:6329,,no data found,,,,,,QseE,,,,,,,67825,Citrobacter rodentium,,,,rodents,10090,Mus musculus (related: house mouse),129S7/SvEvBrd-Hprt<+>,,,colon; gut,adrenergic sensors,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27273829,PubMed,10.1128/mBio.00826-16,MBio. 2016 Jun 7;7(3). pii: e00826-16,vanessa.sperandio@utsouthwestern.edu,,C G Moreira 2016,2016,2 genes,Moreira-2016-Bacterial Adrenergic Sensors Regu,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8278,PHI:6330,UniProt,P36400,GenBank,CAA78443,,,mexicana,cpb,,,,,,,5665,Leishmania mexicana,,MNYC/BZ/62/M379,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,cysteine peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27191844,PubMed,10.1371/journal.ppat.1005658,PLoS Pathog. 2016 May 18;12(5):e1005658,albert.descoteaux@iaf.inrs.ca,"Episomal expression of GP63 enabled the CPB-deficient mutant to establish infection in macrophages, induce the formation of large communal parasitophorous vacuoles, and cause lesions in mice.",P Casgrain 2016,2016,1 gene,Casgrain-2016-Cysteine Peptidase B Regulates L,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8279,PHI:6331,UniProt,G2X6V8,GenBank,EGY14726,,,VdLs.17,VdCYP1,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,cytochrome P450 monooxygenase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27329129,PubMed,10.1038/srep27979,Sci Rep. 2016 Jun 22;6:27979,daixiaofeng@caas.cn,VdCYP1 gene deletion and complementation experiments confirmed that VdCYP1was the pathogenicity-related gene in V. dahliae.,D Zhang 2016,2016,1 gene,Zhang-2016-Identification and characterization,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8280,PHI:6332,UniProt,B5LBI1,GenBank,ACH56227,,,,Rs-cps,,,,,,,46012,Radopholus similis,,,blackhead toppling disease,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,root,cathepsin S cysteine,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27293544,PubMed,10.1186/s13578-016-0107-5,Cell Biosci. 2016 Jun 10;6:39,xiehui@scau.edu.cn,RNAi significantly suppressed the expression level of Rs-cpsand reproductive capability and pathogenicity of R. similis.,K Wang 2016,2016,1 gene,Wang-2016-The cathepsin S cysteine proteinase,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8281,PHI:6333,,no data found,GenBank,ADQ81235,,,DSM 15868,Riean_0060,,,,,,,34085,Riemerella anatipestifer,1455062,YZb1,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood,transaldolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27259827,PubMed,10.1016/j.vetmic.2016.04.014,Vet Microbiol. 2016 Jun 30;189:52-8,huqinghai@caas.cn,,X Ni 2016,2016,2 genes,Ni-2016-Genome-wide mining of potential virule.,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8282,PHI:6334,,no data found,GenBank,ADQ82694,,,DSM 15868,Riean_1537,,,,,,,34085,Riemerella anatipestifer,1455062,YZb1,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27259827,PubMed,10.1016/j.vetmic.2016.04.014,Vet Microbiol. 2016 Jun 30;189:52-8,huqinghai@caas.cn,,X Ni 2016,2016,2 genes,Ni-2016-Genome-wide mining of potential virule.,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8283,PHI:6335,UniProt,Q4G4E4,GenBank,AAX76914,,,PPD130/91,EsaE,,,,,,,636,Edwardsiella tarda,,PPD130/91,hemorrhagic septicemia,bony fishes,96903,Trichopodus trichopterus (related: three spot gourami),,,,,type III secretion system subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27283851,PubMed,10.1016/j.vetmic.2016.05.003,Vet Microbiol. 2016 Jul 15;190:12-8,xieh@ihb.ac.cn,"In blue gourami fish infection model, 87.88% of blue gourami infected with DesaE strain survived whereas only 3.03% survived when infecte with wild-type strain.",Y Zhou 2016,2016,1 gene,Zhou-2016-Edwardsiella tarda EsaE (Orf19 prote,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8284,PHI:6336,UniProt,Q8Y125,EMBL,CAD14570,,,GMI1000,PopP2,,none (wild-type),,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Niederzenz-1,wild-type RRS1-R (resistant background) and wild-type RD19 (cysteine protease),,root (leaf),type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,resistance,,other evidence: wild-type inoculation,,,RP; AC,18708476,PubMed,10.1105/tpc.108.058685,Plant Cell. 2008 Aug;20(8):2252-64,laurent.deslandes@toulouse.inra.fr,"An Arabidopsis rd19 mutant in an RRS1-R genetic background is compromised in resistance to the bacterium, indicating that RD19 is required for RRS1-R-mediated resistance. This study physical interaction between RD19 and PopP2, previous study between Arabidopsis RRS1-R and bacterial PopP2.",M Bernoux 2008,2008,1 gene,"Bernoux-2008-RD19, an Arabidopsis cysteine pro",BATCH_060/AC First host target curation,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8285,PHI:6336,UniProt,Q8Y125,EMBL,CAD14570,,,GMI1000,PopP2,,none (wild-type),,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Niederzenz-1,wild-type RRS1-R (resistant background) and rd19 null mutant (cysteine protease),,root (leaf),type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptibility,,other evidence: host gene disruption; host gene complementation,,,RP; AC,18708476,PubMed,10.1105/tpc.108.058685,Plant Cell. 2008 Aug;20(8):2252-64,laurent.deslandes@toulouse.inra.fr,"An Arabidopsis rd19 mutant in an RRS1-R genetic background is compromised in resistance to the bacterium, indicating that RD19 is required for RRS1-R-mediated resistance. This study physical interaction between RD19 and PopP2, previous study between Arabidopsis RRS1-R and bacterial PopP2.",M Bernoux 2008,2008,1 gene,"Bernoux-2008-RD19, an Arabidopsis cysteine pro",BATCH_060/AC First host target curation,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8286,PHI:6336,UniProt,Q8Y125,EMBL,CAD14570,,,GMI1000,PopP2,,none (wild-type),,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,wild-type RRS1-S (susceptible background) and wild-type RD19 (cysteine protease),,root (leaf),type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptibility,,other evidence: wild-type inoculation,,,RP; AC,18708476,PubMed,10.1105/tpc.108.058685,Plant Cell. 2008 Aug;20(8):2252-64,laurent.deslandes@toulouse.inra.fr,"An Arabidopsis rd19 mutant in an RRS1-R genetic background is compromised in resistance to the bacterium, indicating that RD19 is required for RRS1-R-mediated resistance. This study physical interaction between RD19 and PopP2, previous study between Arabidopsis RRS1-R and bacterial PopP2.",M Bernoux 2008,2008,1 gene,"Bernoux-2008-RD19, an Arabidopsis cysteine pro",BATCH_060/AC First host target curation,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8287,PHI:6336,UniProt,Q8Y125,EMBL,CAD14570,,,GMI1000,PopP2,,none (wild-type),,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,wild-type RRS1-S (susceptible background) and rd19 null mutant (cysteine protease),,root (leaf),type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptibility,,other evidence: host gene disruption,,,RP; AC,18708476,PubMed,10.1105/tpc.108.058685,Plant Cell. 2008 Aug;20(8):2252-64,laurent.deslandes@toulouse.inra.fr,"An Arabidopsis rd19 mutant in an RRS1-R genetic background is compromised in resistance to the bacterium, indicating that RD19 is required for RRS1-R-mediated resistance. This study physical interaction between RD19 and PopP2, previous study between Arabidopsis RRS1-R and bacterial PopP2.",M Bernoux 2008,2008,1 gene,"Bernoux-2008-RD19, an Arabidopsis cysteine pro",BATCH_060/AC First host target curation,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8288,PHI:6336,UniProt,Q8Y125,EMBL,CAD14570; Ensembl: RSc0868,,,GMI1000,PopP2,,full length 488 amino acids used as bait in yeast two-hybrid,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: yeast),ecotype Columbia-0,mixture of RRS1-S and transgenic Col-0 with RRS1-R,,root,type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,RD19 (from Arabidopsis cDNA prey library),UniProt: P43296; GenBank: At4g39090; Ensembl: Ensembl: AT4G39090,interacts in yeast two-hybrid,,other evidence: yeast two-hybrid,,,RP; AC,18708476,PubMed,10.1105/tpc.108.058685,Plant Cell. 2008 Aug;20(8):2252-64,laurent.deslandes@toulouse.inra.fr,"An Arabidopsis rd19 mutant in an RRS1-R genetic background is compromised in resistance to the bacterium, indicating that RD19 is required for RRS1-R-mediated resistance. This study physical interaction between RD19 and PopP2, previous study between Arabidopsis RRS1-R and bacterial PopP2. Root tissue from seedling.",M Bernoux 2008,2008,1 gene,"Bernoux-2008-RD19, an Arabidopsis cysteine pro",BATCH_060/AC First host target curation,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8289,PHI:6336,UniProt,Q8Y125,EMBL,CAD14570; Ensembl: RSc0868,,,GMI1000,PopP2,,PopP2-CFP,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: nicotiana benthamiana),ecotype Columbia-0,,,leaf epidermis,type III type effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,RD19-YFP,UniProt: P43296; GenBank: At4g39090; Ensembl: Ensembl: AT4G39090,positive physical interaction seen with FLIM,,functional test in host: transient expression,Agrobacterium-mediated coexpression of transgenes in N. benthamiana with FLIM/FRET analysis after 48 hours,,RP; AC,18708476,PubMed,10.1105/tpc.108.058685,Plant Cell. 2008 Aug;20(8):2252-64,laurent.deslandes@toulouse.inra.fr,"An Arabidopsis rd19 mutant in an RRS1-R genetic background is compromised in resistance to the bacterium, indicating that RD19 is required for RRS1-R-mediated resistance. This study physical interaction between RD19 and PopP2, previous study between Arabidopsis RRS1-R and bacterial PopP2.",M Bernoux 2008,2008,1 gene,"Bernoux-2008-RD19, an Arabidopsis cysteine pro",BATCH_060/AC First host target curation,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8290,PHI:6337,,no data found,GenBank,AAX16973,,,DAH,bh0463A,,,,,,,140,Borrelia hermsii,314723,DAH,relapsing fever,rodents,10090,Mus musculus (related: house mouse),C.B-17IcrHanHsdArc-Prkdc<scid>,,,blood,DNA adenine methylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,27195796,PubMed,10.1371/journal.pone.0155798,PLoS One. 2016 May 19;11(5):e0155798,tbankhead@vetmed.wsu.edu,"The dam mutant was capable of infecting immunocompetent mice, and the mean level of spirochetemia in immunocompetent mice was not significantly different from wild type B.hermsii.",A E James 2016,2016,1 gene,James-2016-Characterization of a DNA Adenine M,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8291,PHI:6337,,no data found,GenBank,AAX16973,,,DAH,bh0463A,,,,,,,140,Borrelia hermsii,314723,DAH,relapsing fever,rodents,10090,Mus musculus (related: house mouse),C57BL/6NHsd,,,blood,DNA adenine methylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,27195796,PubMed,10.1371/journal.pone.0155798,PLoS One. 2016 May 19;11(5):e0155798,tbankhead@vetmed.wsu.edu,"The dam mutant was capable of infecting immunocompetent mice, and the mean level of spirochetemia in immunocompetent mice was not significantly different from wild type B.hermsii.",A E James 2016,2016,1 gene,James-2016-Characterization of a DNA Adenine M,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8292,PHI:6338,UniProt,D4HVL8,GenBank,CBA19475,,,CFBP1430,HrcU,,,,HrpP,UniProt: D4HVM3,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,type III secretion protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27206522,PubMed,10.1186/s12866-016-0702-y,BMC Microbiol. 2016 May 20;16(1):88,sundin@msu.edu,HrcU and HrpP were shown to be required for disease development in an immature pear infection model and respective mutants were unable to induce a hypersensitive response in tobacco.,R R McNally 2016,2016,2 genes,McNally-2016-HrcU and HrpP are pathogenicity f,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8293,PHI:6339,UniProt,D4HVM3,GenBank,CBA19480,,,CFBP1430,HrpP,,,,HrcU,UniProt: D4HVL8,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,type III secretion protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27206522,PubMed,10.1186/s12866-016-0702-y,BMC Microbiol. 2016 May 20;16(1):88,sundin@msu.edu,HrcU and HrpP were shown to be required for disease development in an immature pear infection model and respective mutants were unable to induce a hypersensitive response in tobacco.,R R McNally 2016,2016,2 genes,McNally-2016-HrcU and HrpP are pathogenicity f,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8294,PHI:6340,UniProt,O53317,GenBank,AIR15951,,,H37Rv,Rv3167c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; lung,transcriptional repressor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27191591,PubMed,10.1371/journal.ppat.1005652,PLoS Pathog. 2016 May 18;12(5):e1005652,vbriken@umd.edu,The increase in necrosis led to an increase in bacterial virulence as reflected in higher bacterial burden and reduced survival of mice infected with MtbdeltaRv3167c.,L Srinivasan 2016,2016,1 gene,Srinivasan-2016-Identification of a Transcript,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8295,PHI:6341,UniProt,Q0P9F1,GenBank,CAL35220,,,ATCC 700819,CsrA,,,,,,,197,Campylobacter jejuni,,PopP2,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),BALB/cByJ,,,,carbon metabolism,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27257952,PubMed,10.1371/journal.pone.0156932,PLoS One. 2016 Jun 3;11(6):e0156932,stthomps@augusta.edu,"The csrA mutant exhibited reduced ability to colonize in a mouse model when in competition with the wild type, further underscoring the role of CsrA inC.jejuni colonization and pathogenesis.",J A Fields 2016,2016,1 gene,Fields-2016-Campylobacter jejuni CsrA Regulate,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8296,PHI:6342,UniProt,A0A077UVP4,GenBank,CDR27197,,,,RpiRc,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Hsd:ND4,,,whole body; skin,metabolic sensor-regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27329753,PubMed,10.1128/mBio.00818-16,MBio. 2016 Jun 21;7(3). pii: e00818-16,victor.torres@nyumc.org,Inactivation of rpiRc phenocopied rot deletion and increased S. Aureus killing of primary human polymorphonuclear leukocytes and the pathogenesis of bloodstream infectionin vivo.,D Balasubramanian 2016,2016,1 gene,Balasubramanian-2016-Staphylococcus aureus Coo,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8297,PHI:6343,UniProt,R9RX08,GenBank,AGM61352,,,IN0017,AVR1-CO39,,"pUASgal4::AVR1-CO39 transgenic rice, DEX inducible",,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,contains Pi-CO39 (allowing recognition of AVR1-CO39),,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,cell death and ROS,other evidence: transgenic plants,,,RP,27289079,PubMed,10.1111/tpj.13231,Plant J. 2016 Jun 11,boris.szurek@ird.fr,"Transgenic rice lines harboring the AVR1-CO39effector gene from the rice blast fungus Magnaporthe oryzae,under the control of an inducible promoter, were challenged with transgenic Xoo and Xoc strains carrying a TAL effector designed to transactivate the inducible promoter. This induced AVR1-CO39expression and triggered BB and BLS resistance when the corresponding Pi-CO39 resistance locus was present.",M Hutin 2016,2016,3 genes,Hutin-2016-Ectopic activation of the rice NLR,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8298,PHI:6343,UniProt,R9RX08,GenBank,AGM61352,,,IN0017,AVR1-CO39,,"pUASgal4::AVR1-CO39 transgenic rice, DEX inducible",,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kanto 51,not containing pi-co39 (no recognition of AVR1-CO39),,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,no cell death no ROS,other evidence: transgenic plants,,,RP,27289079,PubMed,10.1111/tpj.13231,Plant J. 2016 Jun 11,boris.szurek@ird.fr,"Transgenic rice lines harboring the AVR1-CO39effector gene from the rice blast fungus Magnaporthe oryzae,under the control of an inducible promoter, were challenged with transgenic Xoo and Xoc strains carrying a TAL effector designed to transactivate the inducible promoter. This induced AVR1-CO39expression and triggered BB and BLS resistance when the corresponding Pi-CO39 resistance locus was present.",M Hutin 2016,2016,3 genes,Hutin-2016-Ectopic activation of the rice NLR,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8299,PHI:6346,UniProt,A0A0D1E5A8,GenBank,KIS70866,,,521,apB73,chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. B73,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27279632,PubMed,10.1111/mpp.12442,Mol Plant Pathol. 2016 Jun 9,armin.djamei@gmi.oeaw.ac.at,,A Stirnberg 2016,2016,3 genes,"Stirnberg-2016-Characterization of ApB73, a vi",BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8300,PHI:6347,UniProt,A0A0B4ZUY6,GenBank,AJD76950,,,SM1890,NDM-1,,,,,,,562,Escherichia coli,1144303,J53,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,carbapenemase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,functional test in host: transient expression,,,RP,27179815,PubMed,10.1016/j.ijantimicag.2016.02.019,Int J Antimicrob Agents. 2016 Jun;47(6):430-5,axel.hamprecht@uk-koeln.de,The clinica lSerratia marcescens isolate SM1890 containing an ca. 140-kb sized IncA/C-type plasmid (pNDM-1) served as a donor of blaNDM-1,S Göttig 2016,2016,1 gene,Gottig-2016-Impact of blaNDM-1 on fitness and,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8301,PHI:6347,UniProt,A0A0B4ZUY6,GenBank,AJD76950,,,SM1890,NDM-1,,,,,,,573,Klebsiella pneumoniae,1244085,CG43,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,carbapenemase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,functional test in host: transient expression,,,RP,27179815,PubMed,10.1016/j.ijantimicag.2016.02.019,Int J Antimicrob Agents. 2016 Jun;47(6):430-5,axel.hamprecht@uk-koeln.de,The clinica lSerratia marcescens isolate SM1890 containing an ca. 140-kb sized IncA/C-type plasmid (pNDM-1) served as a donor of blaNDM-1,S Göttig 2016,2016,1 gene,Gottig-2016-Impact of blaNDM-1 on fitness and,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8302,PHI:6348,UniProt,G4MTN1,GenBank,EHA55589,,,70-15,MoPmt2,chromosome 2,deltaYAL023c::kanMX4,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,dolichyl-phosphate-mannose-protein mannosyltransferase,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,Congo red; calcofluor white,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27199956,PubMed,10.3389/fmicb.2016.00630,Front Microbiol. 2016 May 2;7:630,kandylemon@163.com,"The MoPmt2 mutants also showed a distinct reduction in fungal growth, which was associated with severe alterations in hyphal polarity.",M Guo 2016,2016,1 gene,Guo-2016-The Pmt2p-Mediated Protein O-Mannosyl,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8303,PHI:6348,UniProt,G4MTN1,GenBank,EHA55589,,,70-15,MoPmt2,chromosome 2,deltaYAL023c::kanMX4,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,dolichyl-phosphate-mannose-protein mannosyltransferase,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,Congo red; calcofluor white,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27199956,PubMed,10.3389/fmicb.2016.00630,Front Microbiol. 2016 May 2;7:630,kandylemon@163.com,"The MoPmt2 mutants also showed a distinct reduction in fungal growth, which was associated with severe alterations in hyphal polarity.",M Guo 2016,2016,1 gene,Guo-2016-The Pmt2p-Mediated Protein O-Mannosyl,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8304,PHI:6350,UniProt,Q83FB9,GenBank,AAO89591,,,RSA 493,cvpB,,,,PI(3)P; phosphatidylserine (PS),"PI(3)P, UniProt: Q83BF9; phosphatidylserine (PS), UniProt: B6J9C5",,777,Coxiella burnetii,,Nine Mile phase II,Q fever,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27226300,PubMed,10.1073/pnas.1522811113,Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):E3260-9,matteo.bonazzi@cpbs.cnrs.fr,C. burnetii secreted effector Coxiella vacuolar protein B (CvpB) binds PI(3)P and phosphatidylserine (PS) on CCVs and early endosomal compartments and perturbs the activity of the phosphatidylinositol 5-kinase PIKfyve to manipulate PI(3)P metabolism.,E Martinez 2016,2016,1 gene,Martinez-2016-Coxiella burnetii effector CvpB,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8305,PHI:6351,UniProt,N1JJH4,GenBank,CCU82362,,,DH14,CSEP0081,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,candidate secreted effector proteins,,,,effector (plant avirulence determinant),,yes,yes,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27322386,PubMed,10.1371/journal.pone.0157586,PLoS One. 2016 Jun 20;11(6):e0157586,htc@plen.ku.dk,Independent silencing of the transcripts for these CSEPs significantly reduced the fungal penetration and haustoria formation rate.,A A Ahmed 2016,2016,2 genes,Ahmed-2016-The Barley Powdery Mildew Effector,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8306,PHI:6352,UniProt,N1J7E2,GenBank,CCU75836,,,DH14,CSEP0254,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,candidate secreted effector proteins,,,,effector (plant avirulence determinant),,yes,yes,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27322386,PubMed,10.1371/journal.pone.0157586,PLoS One. 2016 Jun 20;11(6):e0157586,htc@plen.ku.dk,Independent silencing of the transcripts for these CSEPs significantly reduced the fungal penetration and haustoria formation rate.,A A Ahmed 2016,2016,2 genes,Ahmed-2016-The Barley Powdery Mildew Effector,BATCH_060,2016-07-01,MC,,,,,,,,,,,,,
,,Record 8307,PHI:6353,UniProt,Q87W42,GenBank,AAO58163,,,DC3000,HopG1,,deletion mutant,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,Kinesin (wild-type),UniProt: Q8W5R5; GenBank: BAB71852,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,reduced disease symptoms (host chlorosis),,gene deletion: full; gene complementation,,,RP; AC,27217495,PubMed,10.1104/pp.16.01593,Plant Physiol. 2016 Jul;171(3):2239-55,bday@msu.edu,HopG1 effector interacts with an Arabidopsis mitochondrial localized kinesin motor protein.,M Shimono 2016,2016,2 genes,Shimono-2016-The Pseudomonas syringae type-III,BATCH_060B/AC update,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8308,PHI:6353,UniProt,Q87W42,GenBank,AAO58163,,,DC3000,HopG1,,none (wild-type),,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,Kinesin (SALK_130788 mutant),UniProt: Q8W5R5; GenBank: BAB71852,leaf,type III effector,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: host gene mutation,,,RP; AC,27217495,PubMed,10.1104/pp.16.01593,Plant Physiol. 2016 Jul;171(3):2239-55,bday@msu.edu,HopG1 effector interacts with an Arabidopsis mitochondrial localized kinesin motor protein.,M Shimono 2016,2016,2 genes,Shimono-2016-The Pseudomonas syringae type-III,BATCH_060B/AC update,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8309,PHI:6353,UniProt,Q87W42,GenBank,AAO58163; Ensembl: PSPTO_4727,,,DC3000,HopG1,,T7-HopG1,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress) (non-host bioassay: nicotiana benthamiana),ecotype Columbia-0,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,Kinesin (HA-kinesin),UniProt: Q8W5R5; GenBank: BAB71852; Ensembl: At4g39050,positive co-IP,,functional test in host: transient expression,"Agrobacterium-mediated co-expression by infiltration into Nb, co-IP using either anti-HA or anti-T7 antibodies, western with anti-HA-HRP, anti-T7-HRP or anti-actin",,RP; AC,27217495,PubMed,10.1104/pp.16.01593,Plant Physiol. 2016 Jul;171(3):2239-55,bday@msu.edu,Previously shown to interact in Y2H in Mukhtar et al 2011,M Shimono 2016,2016,2 genes,Shimono-2016-The Pseudomonas syringae type-III,BATCH_060B/AC update,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8310,PHI:6355,UniProt,Q83FB9,GenBank,NP_819077,,,RSA 493,CvpB,,,,,,,777,Coxiella burnetii,,Tn1832,Q fever,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27226300,PubMed,10.1073/pnas.1522811113,Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):E3260-9,matteo.bonazzi@cpbs.cnrs.fr,C. burnetii secreted effector Coxiella vacuolar protein B (CvpB) binds PI(3)P and phosphatidylserine (PS) on CCVs and early endosomal compartments and perturbs the activity of the phosphatidylinositol 5-kinase PIKfyve to manipulate PI(3)P metabolism.,E Martinez 2016,2016,1 gene,Martinez-2016-Coxiella burnetii effector CvpB,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8311,PHI:6356,UniProt,N1JJH4,GenBank,CCU82362,,,DH14,CSEP0081,,,,,,,34373,Blumeria graminis,546991,f. sp. hordei strain DH14,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,putative effector protein,,,,effector (plant avirulence determinant),,yes,yes,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27322386,PubMed,10.1371/journal.pone.0157586,PLoS One. 2016 Jun 20;11(6):e0157586,htc@plen.ku.dk,,A A Ahmed 2016,2016,2 genes,Ahmed-2016-The Barley Powdery Mildew Effector,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8312,PHI:6357,UniProt,N1J7E2,GenBank,CCU75836,,,DH14,CSEP0254,,,,,,,34373,Blumeria graminis,546991,f. sp. hordei strain DH14,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,putative effector protein,,,,effector (plant avirulence determinant),,yes,yes,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27322386,PubMed,10.1371/journal.pone.0157586,PLoS One. 2016 Jun 20;11(6):e0157586,htc@plen.ku.dk,,A A Ahmed 2016,2016,2 genes,Ahmed-2016-The Barley Powdery Mildew Effector,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8313,PHI:6358,UniProt,B8F6T4,GenBank,ACL33036,,,SH0165,HtrA,,,,,,,738,Glaesserella parasuis,,SC1401,Glasser's disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,protease,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,RP,27217419,PubMed,10.1128/IAI.00147-16,Infect Immun. 2016 Jul 21;84(8):2209-19,csanjie@sicau.edu.cn and,Pathogen formerly called Haemophilus parasuis,L Zhang 2016,2016,1 gene,Zhang-2016-HtrA is important for stress resist,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8314,PHI:6359,,no data found,GenBank,KT119835,,,,MFAP1,,,,,,,38448,Monilinia fructicola,,MUK-1,blossom blight; fruit rot,eudicots,3764,Rosa (no common name found),cv. Flaming Peace,,,petal,"redox-responsive transcription factor, a YAP1 homolog",,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,RP,27239957,PubMed,10.1111/mpp.12438,Mol Plant Pathol. 2016 May 30,mhlee@nchu.edu.tw,,P YU 2016,2016,1 gene,Yu-2016-The YAP1 homolog-mediated redox sensin,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8315,PHI:6359,,no data found,GenBank,KT119835,,,,MFAP1,,,,,,,38448,Monilinia fructicola,,MUK-1,blossom blight; fruit rot,eudicots,3760,Prunus persica (related: peach),cv. Tian Tao,,,petal,"redox-responsive transcription factor, a YAP1 homolog",,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,RP,27239957,PubMed,10.1111/mpp.12438,Mol Plant Pathol. 2016 May 30,mhlee@nchu.edu.tw,,P YU 2016,2016,1 gene,Yu-2016-The YAP1 homolog-mediated redox sensin,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8316,PHI:6359,,no data found,GenBank,KT119835,,,,MFAP1,,,,,,,38448,Monilinia fructicola,,MUK-1,blossom blight; fruit rot,eudicots,3764,Rosa (no common name found),cv. Flaming Peace,,,petal,"redox-responsive transcription factor, a YAP1 homolog",,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,RP,27239957,PubMed,10.1111/mpp.12438,Mol Plant Pathol. 2016 May 30,mhlee@nchu.edu.tw,,P YU 2016,2016,1 gene,Yu-2016-The YAP1 homolog-mediated redox sensin,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8317,PHI:6359,,no data found,GenBank,KT119835,,,,MFAP1,,,,,,,38448,Monilinia fructicola,,MUK-1,blossom blight; fruit rot,eudicots,3760,Prunus persica (related: peach),cv. Tian Tao,,,petal,"redox-responsive transcription factor, a YAP1 homolog",,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,RP,27239957,PubMed,10.1111/mpp.12438,Mol Plant Pathol. 2016 May 30,mhlee@nchu.edu.tw,,P YU 2016,2016,1 gene,Yu-2016-The YAP1 homolog-mediated redox sensin,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8318,PHI:6360,UniProt,A0A0U1YUA0,GenBank,AJF38888,,,LMG20103,flgK,,,,,,,553,Pantoea ananatis,706191,LMG 20103,,monocots,4679,Allium cepa (related: onion),cv. Texas Grano,,,leaf,flagellar motility,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,27226224,PubMed,10.1111/mpp.12432,Mol Plant Pathol. 2016 May 25,teresa.coutinho@fabi.up.ac.za,,T Weller-Stuart 2016,2016,4 genes,Weller-Stuart-2016-Swimming and twitching moti,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8319,PHI:6361,UniProt,A0A0E9B8Z9,GenBank,AJF38889,,,LMG20103,motA,,,,,,,553,Pantoea ananatis,706191,LMG 20103,,monocots,4679,Allium cepa (related: onion),cv. Texas Grano,,,leaf,flagellar motility,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,27226224,PubMed,10.1111/mpp.12432,Mol Plant Pathol. 2016 May 25,teresa.coutinho@fabi.up.ac.za,,T Weller-Stuart 2016,2016,4 genes,Weller-Stuart-2016-Swimming and twitching moti,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8320,PHI:6362,UniProt,A0A0U1YU94,GenBank,AJF38890,,,LMG20103,pilA,,,,,,,553,Pantoea ananatis,706191,LMG 20103,,monocots,4679,Allium cepa (related: onion),cv. Texas Grano,,,leaf,twitching motility,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,27226224,PubMed,10.1111/mpp.12432,Mol Plant Pathol. 2016 May 25,teresa.coutinho@fabi.up.ac.za,,T Weller-Stuart 2016,2016,4 genes,Weller-Stuart-2016-Swimming and twitching moti,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8321,PHI:6363,UniProt,A0A0U1YU79,GenBank,AJF38891,,,,pilT,,,,,,,553,Pantoea ananatis,706191,LMG 20103,,monocots,4679,Allium cepa (related: onion),cv. Texas Grano,,,leaf,twitching motility,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,27226224,PubMed,10.1111/mpp.12432,Mol Plant Pathol. 2016 May 25,teresa.coutinho@fabi.up.ac.za,,T Weller-Stuart 2016,2016,4 genes,Weller-Stuart-2016-Swimming and twitching moti,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8322,PHI:6364,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,PopP2,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,acetyltransferase effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,26000483,PubMed,10.1016/j.cell.2015.04.025,Cell. 2015 May 21;161(5):1074-88,laurent.deslandes@toulouse.inra.fr,,C Le Roux 2015,2015,1 gene,Le Roux-2015-A receptor pair with an integrate,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8323,PHI:6365,UniProt,Q886L1,GenBank,AAO55088,,,DC3000,HopAF1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,plasma membrane,functional test in host: transient expression,,,RP,27274076,PubMed,10.1073/pnas.1606322113,Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):E3577-86,dangl@email.unc.edu,HopAF1 Associates with Arabidopsis MTN Proteins at the plasma membrane.,E J Washington 2016,2016,1 gene,Washington-2016-Pseudomonas syringae type III,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8324,PHI:6366,UniProt,Q8ZMX2,GenBank,AAL21545,,,LT2,Pat,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,protein lysine acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27341691,PubMed,10.1111/mmi.13451,Mol Microbiol. 2016 Jun 24,ch346@cornell.edu,Acyltransferase Pat post-transcriptionally controls HilD to repress Salmonella invasion,C Hung 2016,2016,1 gene,Hung-2016-The protein acyltransferase Pat post,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8325,PHI:6367,UniProt,Q8YF53,GenBank,AAL52855,,,16M,tcpB,,,,,,,29459,Brucella melitensis,224914,16M,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood plasma,TIR-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27289452,PubMed,10.1016/j.ijmm.2016.05.003,Int J Med Microbiol. 2016 May 28. pii: S1438-4221(16)30057-1,zeliangchen@yahoo.com,"TB-8 and TB-9 rescue the virulence of Brucella tcpB mutants at the cellular level, indicating key roles of the DD loop in Brucella pathogenesis.",Y Ke 2016,2016,1 gene,Ke-2016-Inhibition of TLR4 signaling by Brucel,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8326,PHI:6368,UniProt,M1GM60,GenBank,AGE15681,,,AF421,SnTox3,,,,,,,13684,Parastagonospora nodorum,,,Septoria nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. BG220,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27258471,PubMed,10.1111/tpj.13228,Plant J. 2016 Jun 3,peter.solomon@anu.edu.au,SnTox3 interacts with a wheat pathogenicity related-1 protein (TaPR-1-1),S Breen 2016,2016,1 gene,Breen-2016-Wheat PR-1 proteins are targeted by,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8327,PHI:6369,UniProt,P0ACF8,GenBank,CAA30530,,,,hns,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,global DNA-binding transcriptional dual regulator,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,27173635,PubMed,10.1016/j.gene.2016.05.007,Gene. 2016 Aug 22;588(2):115-23,nijinjing45@163.com,"The wild type strain, it exhibited the higher ability to colonize mice gut and became more virulent to BALB/c mice. The BALB/c mice infected with the deletion mutant of hns showed a lower survival rate, and a higher bacterial burden in the gut, compared with those infected with wild type strain, especially when the gut microbiota was not disturbed by antibiotic administration.",B Wan 2016,2016,1 gene,Wan-2016-Global transcriptional regulation by,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8328,PHI:6370,UniProt,Q4K505,GenBank,AAY94812,,,Pf-5,vfr,,,,,,,294,Pseudomonas fluorescens,,FD6,opportunistic infection,monocots,4565,Triticum aestivum (related: bread wheat),,,,root,virulence regulator,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation; gene complementation,,,RP,27296968,PubMed,10.1016/j.micres.2016.04.013,Microbiol Res. 2016 Jul-Aug;188-189:106-12,zqx817@sohu.com,"The vfr mutation also increased biofilm production, swimming motility and the expression of exopolysaccharideassociated gene (pelA, pslA and pslB) transcripts, but reduced protease production.",Q Zhang 2016,2016,1 gene,Zhang-2016-Role of Vfr in the regulation of an,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8329,PHI:6371,UniProt,Q5GVN1,GenBank,AAW77242,,,KACC 10331,dgcA,,,,,,,347,Xanthomonas oryzae,291331,pv. oryzae strain KACC 10331,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,decreased,,no,,,,,,,gene mutation; gene complementation,,,RP,27193392,PubMed,10.1038/srep25978,Sci Rep. 2016 May 19;6:25978,hejin@mail.hzau.edu.cn,"DgcA negatively affected virulence, EPS production, bacterial autoaggregation and motility, but positively triggered biofilm formation via modulating the intracellular c-di-GMP levels.",J Su 2016,2016,1 gene,"Su-2016-DgcA, a diguanylate cyclase from Xanth",BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8330,PHI:6371,UniProt,Q5GVN1,GenBank,AAW77242,,,KACC 10331,dgcA,,,,,,,347,Xanthomonas oryzae,291331,pv. oryzae strain KACC 10331,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Zhonghua 11,,,leaf,diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,decreased,,no,,,,,,,gene mutation; gene complementation,,,RP,27193392,PubMed,10.1038/srep25978,Sci Rep. 2016 May 19;6:25978,hejin@mail.hzau.edu.cn,"DgcA negatively affected virulence, EPS production, bacterial autoaggregation and motility, but positively triggered biofilm formation via modulating the intracellular c-di-GMP levels.",J Su 2016,2016,1 gene,"Su-2016-DgcA, a diguanylate cyclase from Xanth",BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8331,PHI:6371,UniProt,Q5GVN1,GenBank,AAW77242,,,KACC 10331,dgcA,,,,,,,347,Xanthomonas oryzae,291331,pv. oryzae strain KACC 10331,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,diguanylate cyclase,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,27193392,PubMed,10.1038/srep25978,Sci Rep. 2016 May 19;6:25978,hejin@mail.hzau.edu.cn,"DgcA negatively affected virulence, EPS production, bacterial autoaggregation and motility, but positively triggered biofilm formation via modulating the intracellular c-di-GMP levels.",J Su 2016,2016,1 gene,"Su-2016-DgcA, a diguanylate cyclase from Xanth",BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8332,PHI:6371,UniProt,Q5GVN1,GenBank,AAW77242,,,KACC 10331,dgcA,,,,,,,347,Xanthomonas oryzae,291331,pv. oryzae strain KACC 10331,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Zhonghua 11,,,leaf,diguanylate cyclase,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,27193392,PubMed,10.1038/srep25978,Sci Rep. 2016 May 19;6:25978,hejin@mail.hzau.edu.cn,"DgcA negatively affected virulence, EPS production, bacterial autoaggregation and motility, but positively triggered biofilm formation via modulating the intracellular c-di-GMP levels.",J Su 2016,2016,1 gene,"Su-2016-DgcA, a diguanylate cyclase from Xanth",BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8333,PHI:6372,UniProt,Q9KL16,GenBank,AF409091_1,,,SG24,CspV,,,,,,,666,Vibrio cholerae,686,El Tor,cholera,crustaceans,35525,Daphnia magna (no common name found),,,,,cold shock protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,27208110,PubMed,10.1128/AEM.00807-16,Appl Environ Microbiol. 2016 Jun 30;82(14):4441-52,fyildiz@ucsc.edu,"The mutant is defective in adhesion to the crustacean, however can spread same as wild type. Reduced killing of the microbiota growing on the crustacean was observed.",L Townsley 2016,2016,1 gene,Townsley-2016-Response of Vibrio cholerae to l,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8334,PHI:6373,UniProt,Q9I648,GenBank,AE004484_11,,,PAO1,fiuA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,lung,ferrichrome receptor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,27190289,PubMed,10.1093/femsle/fnw104,FEMS Microbiol Lett. 2016 Jun;363(11). pii: fnw104,sangsun_yoon@yuhs.ac,,K Lee 2016,2016,1 gene,Lee-2016-The ferrichrome receptor A as a new t,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8335,PHI:6374,UniProt,Q572D3,GenBank,ADC96691; Ensembl: PITG_14371,,,,Avr3a,,pEXP32-AVR3a bait in Yeast two-hybrid,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato)(non-host bioassay: yeast),,,,,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,StCMPG1a from potato Yeast two-hyrid prey library,UniProt: D7RX03,positive binding yeast two-hybrid,,other evidence: yeast two-hybrid,,,RP; AC,20457921,PubMed,10.1073/pnas.0914408107,Proc Natl Acad Sci U S A. 2010 May 25;107(21):9909-14,pbirch@scri.ac.uk,"AVR3a interacts with and stabilizes host U-box E3 ligase CMPG1, which is required for ICD {(INF1)-triggered cell death (ICD)}.",J I B Bos 2010,2010,2 genes,Bos-2010-Phytophthora infestans effector AVR3a,BATCH_060B/AC update first host target,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8336,PHI:6374,UniProt,Q572D3,GenBank,ADC96691; Ensembl: PITG_14371,,,,Avr3a,,N/C-YFP-Avr3a,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato)(non-host bioassay: Nicotiana benthamiana),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,StCMPG1b-N/C-YFP,UniProt: D7RX04; Ensembl: PGSC0003DMG400022775,positive YFP fluorescence,,other evidence,co-expression in N. benthamiana and BiFC assays using split YFP constructs,,RP; AC,20457921,PubMed,10.1073/pnas.0914408107,Proc Natl Acad Sci U S A. 2010 May 25;107(21):9909-14,pbirch@scri.ac.uk,"AVR3a interacts with and stabilizes host U-box E3 ligase CMPG1, which is required for ICD {(INF1)-triggered cell death (ICD)}.",J I B Bos 2010,2010,2 genes,Bos-2010-Phytophthora infestans effector AVR3a,BATCH_060B/AC update first host target,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8337,PHI:6374,UniProt,Q572D3,GenBank,ADC96691,,,,Avr3a,,CS12 Avr3a silenced line,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Bintje,,,leaf,effector (plant avirulence determinant),,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP; AC,20457921,PubMed,10.1073/pnas.0914408107,Proc Natl Acad Sci U S A. 2010 May 25;107(21):9909-14,pbirch@scri.ac.uk,"AVR3a interacts with and stabilizes host U-box E3 ligase CMPG1, which is required for ICD {(INF1)-triggered cell death (ICD)}.",J I B Bos 2010,2010,2 genes,Bos-2010-Phytophthora infestans effector AVR3a,BATCH_060B/AC update first host target,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8338,PHI:6376,UniProt,Q9FCY7,GenBank,AF282857_16,,,SS104,WtsE,,,,,,,66269,Pantoea stewartii,66271,subsp. stewartii,Stewart's wilt; leaf blight (maize),monocots,4577,Zea mays (related: maize),,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27191168,PubMed,10.1371/journal.ppat.1005609,PLoS Pathog. 2016 May 18;12(5):e1005609,mackey.86@osu.edu,These effectors associate with host protein phosphatase 2A (PP2A) heterotrimeric enzyme complexes via direct interaction with B' regulatory subunits,L Jin 2016,2016,3 genes,Jin-2016-Direct and Indirect Targeting of PP2A,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8339,PHI:6377,UniProt,Q887C9,GenBank,NP_791204,,,DC3000,AvrE1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27191168,PubMed,10.1371/journal.ppat.1005609,PLoS Pathog. 2016 May 18;12(5):e1005609,mackey.86@osu.edu,These effectors associate with host protein phosphatase 2A (PP2A) heterotrimeric enzyme complexes via direct interaction with B' regulatory subunits,L Jin 2016,2016,3 genes,Jin-2016-Direct and Indirect Targeting of PP2A,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8340,PHI:6378,UniProt,Q887D0,GenBank,AAF71501,,,DC3000,HopM1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27191168,PubMed,10.1371/journal.ppat.1005609,PLoS Pathog. 2016 May 18;12(5):e1005609,mackey.86@osu.edu,These effectors associate with host protein phosphatase 2A (PP2A) heterotrimeric enzyme complexes via direct interaction with B' regulatory subunits,L Jin 2016,2016,3 genes,Jin-2016-Direct and Indirect Targeting of PP2A,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8341,PHI:6379,UniProt,A0A0E3GIM3,GenBank,AJR19786,,,,HgGLAND18,,,,,,,51029,Heterodera glycines,,,,eudicots,3847,Glycine max (related: soybean),cv. Essex,,,root,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27265684,PubMed,10.1111/nph.14047,New Phytol. 2016 Jun 6,tbaum@iastate.edu,HgGLAND18 is necessary for pathogenicity in compatible interactions with soybean.,J B Noon 2016,2016,1 gene,Noon-2016-A Plasmodium-like virulence effector,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8342,PHI:6380,UniProt,E9F1A7,GenBank,EFY98917,,,ARSEF 23,mrLPAAT1,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,lysophosphatidate acyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,27312218,PubMed,10.1111/1462-2920.13408,Environ Microbiol. 2016 Jun 17,cswang@sibs.ac.cn,"Lysophosphatidate acyltransferase mrLPAAT1 was required for fungal growth, cell differentiation, maintenance of cell polarity and virulence.",Q Gao 2016,2016,1 gene,Gao-2016-Phospholipid homeostasis maintains ce,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8343,PHI:6380,UniProt,E9F1A7,GenBank,EFY98917,,,ARSEF 23,mrLPAAT1,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,lysophosphatidate acyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,27312218,PubMed,10.1111/1462-2920.13408,Environ Microbiol. 2016 Jun 17,cswang@sibs.ac.cn,"Lysophosphatidate acyltransferase mrLPAAT1 was required for fungal growth, cell differentiation, maintenance of cell polarity and virulence.",Q Gao 2016,2016,1 gene,Gao-2016-Phospholipid homeostasis maintains ce,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8344,PHI:6381,UniProt,Q5ZUY9,GenBank,AAU27733,,,Philadelphia 1,iolT,,,,,,,446,Legionella pneumophila,,JR32,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),ATCC 30234,,,,inositol transporter,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27287324,PubMed,10.1128/AEM.01018-16,Appl Environ Microbiol. 2016 Jul 29;82(16):5000-14,hilbi@imm.uzh.ch,,C Manske 2016,2016,2 genes,Manske-2016-Metabolism of myo-inositol by Legi,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8345,PHI:6382,UniProt,Q5ZUZ0,GenBank,AAU27732,,,Philadelphia 1,iolG,,,,,,,446,Legionella pneumophila,,JR32,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),ATCC 30234,,,,inositol-2-dehydrogenase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27287324,PubMed,10.1128/AEM.01018-16,Appl Environ Microbiol. 2016 Jul 29;82(16):5000-14,hilbi@imm.uzh.ch,,C Manske 2016,2016,2 genes,Manske-2016-Metabolism of myo-inositol by Legi,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8346,PHI:6383,UniProt,A0A0D5YID2,GenBank,AKA31704,,,AB5075-UW,adeA,,,,,,PHI:6384; PHI:6385,470,Acinetobacter baumannii,,BM4587,pneumonia; bloodstream infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung; liver; spleen,multidrug efflux protein,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,27247231,PubMed,10.1128/mBio.00697-16,MBio. 2016 May 31;7(3). pii: e00697-16,catherine.grillot-courvalin@pasteur.fr,,E Yoon 2016,2016,6 genes,Yoon-2016-Contribution of the Ade Resistance-N,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8347,PHI:6384,UniProt,Q2FD70,GenBank,CAJ77844,,,AYE,adeB,,,,,,PHI:6383; PHI:6385,470,Acinetobacter baumannii,,BM4587,pneumonia; bloodstream infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung; liver; spleen,multidrug efflux protein,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,27247231,PubMed,10.1128/mBio.00697-16,MBio. 2016 May 31;7(3). pii: e00697-16,catherine.grillot-courvalin@pasteur.fr,,E Yoon 2016,2016,6 genes,Yoon-2016-Contribution of the Ade Resistance-N,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8348,PHI:6385,UniProt,Q2FD69,GenBank,CAJ77843,,,AYE,adeC,,,,,,PHI:6383; PHI:6384,470,Acinetobacter baumannii,,BM4587,pneumonia; bloodstream infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung; liver; spleen,multidrug efflux protein,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,27247231,PubMed,10.1128/mBio.00697-16,MBio. 2016 May 31;7(3). pii: e00697-16,catherine.grillot-courvalin@pasteur.fr,,E Yoon 2016,2016,6 genes,Yoon-2016-Contribution of the Ade Resistance-N,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8349,PHI:6386,UniProt,Q2FD95,GenBank,AAX14801,,,BM4454,adeI,,,,,,PHI:6387; PHI:6388,470,Acinetobacter baumannii,,BM4587,pneumonia; bloodstream infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung; liver; spleen,multidrug efflux protein,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,27247231,PubMed,10.1128/mBio.00697-16,MBio. 2016 May 31;7(3). pii: e00697-16,catherine.grillot-courvalin@pasteur.fr,,E Yoon 2016,2016,6 genes,Yoon-2016-Contribution of the Ade Resistance-N,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8350,PHI:6387,UniProt,Q24LT7,GenBank,AAX14802,,,BM4454,adeJ,,,,,,PHI:6386; PHI:6388,470,Acinetobacter baumannii,,BM4587,pneumonia; bloodstream infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung; liver; spleen,multidrug efflux protein,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,27247231,PubMed,10.1128/mBio.00697-16,MBio. 2016 May 31;7(3). pii: e00697-16,catherine.grillot-courvalin@pasteur.fr,,E Yoon 2016,2016,6 genes,Yoon-2016-Contribution of the Ade Resistance-N,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8351,PHI:6388,UniProt,Q24LT6,GenBank,AAX14803,,,BM4454,adeK,,,,,,PHI:6386; PHI:6387,470,Acinetobacter baumannii,,BM4587,pneumonia; bloodstream infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung; liver; spleen,multidrug efflux protein,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,27247231,PubMed,10.1128/mBio.00697-16,MBio. 2016 May 31;7(3). pii: e00697-16,catherine.grillot-courvalin@pasteur.fr,,E Yoon 2016,2016,6 genes,Yoon-2016-Contribution of the Ade Resistance-N,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8352,PHI:6389,UniProt,Q6LAD6,GenBank,CAA79815,,,JL1065,AvrRpt2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27208280,PubMed,10.1104/pp.16.0033,Plant Physiol. 2016 Jul;171(3):2223-38,jlee@ipb-halle.de,"AvrRpt2 specifically suppresses flagellin-induced phosphorylation of Arabidopsis MPK4 and MPK11, but not MPK3 or MPK6.",J Lee 2016,2016,1 gene,Eschen-Lippold-2016-Bacterial AvrRpt2-like cys,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8353,PHI:6390,UniProt,G4N4F9,GenBank,EHA52827,,,70-15,CBP1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,chitin deacetylase,,,,unaffected pathogenicity,,yes,,,,,,,,no,,,,,,,gene mutation,,,RP,27315248,PubMed,10.1371/journal.ppat.1005703,PLoS Pathog. 2016 Jun 17;12(6):e1005703.,S.J.Gurr@exeter.ac.uk,"Germlings of the deletion strains showed loss of chitin deacetylation, and were compromised in their ability to adhere and form appressoria on artificial hydrophobic surfaces.",I A Geoghegan 2016,2016,3 genes,Geoghegan-2016-Chitosan Mediates Germling Adhe,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8354,PHI:6391,UniProt,A0A151V4F3,GenBank,KYQ30446,,,70-15,CDA2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,chitin deacetylase,,,,unaffected pathogenicity,,yes,,,,,,,,no,,,,,,,gene mutation,,,RP,27315248,PubMed,10.1371/journal.ppat.1005703,PLoS Pathog. 2016 Jun 17;12(6):e1005703.,S.J.Gurr@exeter.ac.uk,"Germlings of the deletion strains showed loss of chitin deacetylation, and were compromised in their ability to adhere and form appressoria on artificial hydrophobic surfaces.",I A Geoghegan 2016,2016,3 genes,Geoghegan-2016-Chitosan Mediates Germling Adhe,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8355,PHI:6392,UniProt,G4NFA4,GenBank,EHA47286,,,70-15,CDA3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,glycosyl hydrolase,,,,unaffected pathogenicity,,yes,,,,,,,,no,,,,,,,gene mutation,,,RP,27315248,PubMed,10.1371/journal.ppat.1005703,PLoS Pathog. 2016 Jun 17;12(6):e1005703.,S.J.Gurr@exeter.ac.uk,"Germlings of the deletion strains showed loss of chitin deacetylation, and were compromised in their ability to adhere and form appressoria on artificial hydrophobic surfaces.",I A Geoghegan 2016,2016,3 genes,Geoghegan-2016-Chitosan Mediates Germling Adhe,BATCH_060B,2016-08-01,MC,,,,,,,,,,,,,
,,Record 8356,PHI:6393,UniProt,G4NGX5,GenBank,EHA47485,,,70-15,Morfx1,,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,regulatory factor,,,,reduced virulence,no,yes,,,,reduced; aberrant,,reduced; aberrant,reduced,no,hydrogen peroxide; hydroxyurea; methyl methanesulfonate; cisplatin; bleomycin; Congo red; calcofluor white; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; cisplatin: CHEBI:27899; bleomycin: CHEBI:22907; congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,RP,27434465,PubMed,10.1111/mpp.12461,Mol Plant Pathol. 2016 Jul 19,jplu@zju.edu.cn,"deltaMorfx1 displayed increased sensitivity to UV light, 4 DNA-damaging agents, and 3 cell wall perturbing compounds. However, deltaMorfx1 showed decreased sensitivity to bleomycin.",D Sun 2016,2016,1 gene,Sun-2016-The regulatory factor X protein Morfx,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8357,PHI:6394,UniProt,Q9PK05,GenBank,AAF39490,,,Nigg,TC0668,,,,,,,83560,Chlamydia muridarum,1434769,Nigg3,pneumonitis; upper genital tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,oviduct,upper genital tract pathogenicity factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26597987,PubMed,10.1128/IAI.01171-15,Infect Immun. 2015 Nov 23;84(2):467-79,Zhongg@UTHSCSA.edu,"Intracellular growth and infectivity of C. muridarum in vitro remain unaffected in the absence of TC0668. Intravaginal inoculation of the TC0668 null mutant into C3H/HeJ mice results in a typical course of lower genital tract infection but, unlike a pathogenic isogenic control, is unable to elicit significant chronic inflammation of the oviduct and fails to induce hydrosalpinx.",T A Conrad 2015,2015,1 gene,Conrad-2015-The chromosome-encoded hypothetica,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8358,PHI:6395,UniProt,G4MV40,GenBank,EHA54055,,,70-15,MoALR2,,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. HR-12,,,leaf,CorA transporter,,,,reduced virulence,,yes,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27416318,PubMed,10.1371/journal.pone.0159244,PLoS One. 2016 Jul 14;11(7):e0159244,bharat.chattoo@bcmsu.ac.in,MoALR2 is essentail for infection; MoMNR2 but has limited effect on surface hydrophobicity and severity of plant infection.,M H Reza 2016,2016,2 genes,Reza-2016-Magnesium Uptake by CorA Transporter,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8359,PHI:6396,UniProt,G4MR33,GenBank,EHA57365,,,70-15,MoMNR2,,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. HR-12,,,leaf,CorA transporter,,,,reduced virulence,,no,,,,wild type,,reduced; aberrant,reduced,no,,,,,,,gene mutation,,,RP,27416318,PubMed,10.1371/journal.pone.0159244,PLoS One. 2016 Jul 14;11(7):e0159244,bharat.chattoo@bcmsu.ac.in,MoALR2 is essentail for infection; MoMNR2 but has limited effect on surface hydrophobicity and severity of plant infection.,M H Reza 2016,2016,2 genes,Reza-2016-Magnesium Uptake by CorA Transporter,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8360,PHI:6397,UniProt,Q9I324,GenBank,AE004597_11,,,PAO1,popB,,,,,,PHI:6398,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; lung,fT3SS: insuring bacterial motility,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: chemical inhibition,,,RP,27412581,PubMed,10.1093/infdis/jiw295,J Infect Dis. 2016 Oct 1;214(7):1105-16,francoise.vanbambeke@uclouvain.be,INP1855 acts by dual inhibition of iT3SS and fT3SS and represents a promising therapeutic approach,A Anantharajah 2016,2016,5 genes,Anantharajah-2016-Inhibition of the injectisom,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8361,PHI:6398,UniProt,Q9I323,GenBank,AE004597_12,,,PAO1,popD,,,,,,PHI:6397,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; lung,fT3SS: insuring bacterial motility,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: chemical inhibition,,,RP,27412581,PubMed,10.1093/infdis/jiw295,J Infect Dis. 2016 Oct 1;214(7):1105-16,francoise.vanbambeke@uclouvain.be,INP1855 acts by dual inhibition of iT3SS and fT3SS and represents a promising therapeutic approach,A Anantharajah 2016,2016,5 genes,Anantharajah-2016-Inhibition of the injectisom,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8362,PHI:6399,UniProt,P26993,GenBank,AAA25816,,,388,exsA,,,,,,,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; lung,iT3SS: translocating effectors in the host cells,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: chemical inhibition,,,RP,27412581,PubMed,10.1093/infdis/jiw295,J Infect Dis. 2016 Oct 1;214(7):1105-16,francoise.vanbambeke@uclouvain.be,INP1855 acts by dual inhibition of iT3SS and fT3SS and represents a promising therapeutic approach,A Anantharajah 2016,2016,5 genes,Anantharajah-2016-Inhibition of the injectisom,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8363,PHI:6400,UniProt,Q9I321,GenBank,AE004598_2,,,PAO1,exsD,,,,,,,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; lung,iT3SS: translocating effectors in the host cells,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: chemical inhibition,,,RP,27412581,PubMed,10.1093/infdis/jiw295,J Infect Dis. 2016 Oct 1;214(7):1105-16,francoise.vanbambeke@uclouvain.be,INP1855 acts by dual inhibition of iT3SS and fT3SS and represents a promising therapeutic approach,A Anantharajah 2016,2016,5 genes,Anantharajah-2016-Inhibition of the injectisom,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8364,PHI:6401,UniProt,Q9I322,GenBank,AE004597_14,,,PAO1,exsE,,,,,,,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; lung,iT3SS: translocating effectors in the host cells,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: chemical inhibition,,,RP,27412581,PubMed,10.1093/infdis/jiw295,J Infect Dis. 2016 Oct 1;214(7):1105-16,francoise.vanbambeke@uclouvain.be,INP1855 acts by dual inhibition of iT3SS and fT3SS and represents a promising therapeutic approach,A Anantharajah 2016,2016,5 genes,Anantharajah-2016-Inhibition of the injectisom,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8365,PHI:6402,UniProt,A0A1B0RFQ0,,,,,,Avr4,,,,,,,685502,Pseudocercospora fuligena,,,black leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. LA3940,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27401545,PubMed,10.1105/tpc.15.00893,Plant Cell. 2016 Aug;28(8):1945-65,istergiopoulos@ucdavis.edu,"Structure-guided site-directed mutagenesis indicated that residues in Pf-Avr4 important for binding chitin do not directly influence recognition by Cf-4, and further suggested that the property of recognition is structurally separated, or does not fully overlap with the virulence function of the effector.",A C Kohler 2016,2016,1 gene,Kohler-2016-Structural analysis of an Avr4 eff,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8366,PHI:6403,UniProt,Q56928,GenBank,BAA05952,,,86-8,hfq,,,,,,,630,Yersinia enterocolitica,1194086,WA-314,yersiniosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,multiple regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27387855,PubMed,10.1038/srep29275,Sci Rep. 2016 Jul 8;6:29275,rossier@mvp.unimuenchen.de,Hfq is a global coordinator of surface virulence determinants in Y. enterocolitica suggesting that it constitutes an attractive target for developing new antimicrobial strategies.,T K Kakoschke 2016,2016,1 gene,Kakoschke-2016-The RNA Chaperone Hfq Is Essent,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8367,PHI:6404,,no data found,GenBank,XP_001547339,,,B05.10,BcMtg2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,assembling ribosomal subunits,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,Congo red,congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27346661,PubMed,10.1038/srep28673,Sci Rep. 2016 Jun 27;6:28673,changjun-chen@njau.edu.cn,"The BcMtg2 deletion mutant showed a defect in spore production, conidial germination and sclerotial formation. Additionally, the mutant increased sensitivity to various environmental stresses. The BcMtg2 mutant exhibited dramatically decreased virulence on host plant tissues.",W Shao 2016,2016,1 gene,Shao-2016-BcMtg2 is required for multiple stre,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8368,PHI:6404,,no data found,GenBank,XP_001547339,,,B05.10,BcMtg2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,assembling ribosomal subunits,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,Congo red,congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27346661,PubMed,10.1038/srep28673,Sci Rep. 2016 Jun 27;6:28673,changjun-chen@njau.edu.cn,"The BcMtg2 deletion mutant showed a defect in spore production, conidial germination and sclerotial formation. Additionally, the mutant increased sensitivity to various environmental stresses. The BcMtg2 mutant exhibited dramatically decreased virulence on host plant tissues.",W Shao 2016,2016,1 gene,Shao-2016-BcMtg2 is required for multiple stre,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8369,PHI:6404,,no data found,GenBank,XP_001547339,,,B05.10,BcMtg2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,assembling ribosomal subunits,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,Congo red,congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27346661,PubMed,10.1038/srep28673,Sci Rep. 2016 Jun 27;6:28673,changjun-chen@njau.edu.cn,"The BcMtg2 deletion mutant showed a defect in spore production, conidial germination and sclerotial formation. Additionally, the mutant increased sensitivity to various environmental stresses. The BcMtg2 mutant exhibited dramatically decreased virulence on host plant tissues.",W Shao 2016,2016,1 gene,Shao-2016-BcMtg2 is required for multiple stre,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8370,PHI:6404,,no data found,GenBank,XP_001547339,,,B05.10,BcMtg2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,assembling ribosomal subunits,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,Congo red,congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,RP,27346661,PubMed,10.1038/srep28673,Sci Rep. 2016 Jun 27;6:28673,changjun-chen@njau.edu.cn,"The BcMtg2 deletion mutant showed a defect in spore production, conidial germination and sclerotial formation. Additionally, the mutant increased sensitivity to various environmental stresses. The BcMtg2 mutant exhibited dramatically decreased virulence on host plant tissues.",W Shao 2016,2016,1 gene,Shao-2016-BcMtg2 is required for multiple stre,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8371,PHI:6405,UniProt,A0A0Y9VPZ6,GenBank,CXI25376,,,K173,hmgb2,,,,,,,5821,Plasmodium berghei,5823,ANKA,cerebral malaria,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,chromatin remodeling and transcription regulation,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25916985,PubMed,10.1128/IAI.03129-14,Infect Immun. 2015 Jul;83(7):2771-84,catherine.vaquero@upmc.fr,"P. berghei ANKA lacking the hmgb2 gene (hmgb2 ANKA), an effect associated with a reduction of histological brain lesions and with lower expression levels of several proinflammatory genes.",S Briquet 2015,2015,1 gene,Briquet-2015-Disruption of Parasite hmgb2 Gene,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8372,PHI:6406,UniProt,A0A0H2ZMA3,GenBank,ABJ54247,,,D39,CpsR,,,,cps promotor,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,nasopharynx,glucose sensing regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,27386955,PubMed,10.1038/srep29255,Sci Rep. 2016 Jul 8;6:29255,yibingyin56@126.com,Animal experiments showed that CpsR-cpsp interaction was necessary for both pneumococcal colonization and invasive infection.,K Wu 2016,2016,1 gene,"Wu-2016-CpsR, a GntR family regulator, transcr",BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8373,PHI:6407,UniProt,E8XKZ3,GenBank,ADX18647,,,ST4/74,AvrA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium,salmonellosis,birds,9031,Gallus gallus (related: chicken),,,,liver; cecum,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26574031,PubMed,10.3382/ps/pev344,Poult Sci. 2016 Feb;95(2):354-63,rja@udel.edu,,R J Arsenault 2015,2015,1 gene,Arsenault-2015-Wild-type and mutant AvrA- Salm,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8374,PHI:6408,UniProt,I1RMW3,GenBank,CEF87389,,,PH-1,FgCdc3,chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,cell division control protein,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27387218,PubMed,10.1016/j.fgb.2016.07.005,Fungal Genet Biol. 2016 Sep;94:79-87,wangzh@fafu.edu.cn,"The loss of FgCdc3, FgCdc11, FgCdc12, but not FgCdc10, mutants showed significant reduction in growth, conidiation and virulence. Microscopic analyses revealed that all of them were involved in septum formation and nuclear division. Moreover, disruption of septin genes resulted in morphological defects in ascospores and conidia.",A Chen 2016,2016,4 genes,Chen-2016-Septins are involved in nuclear divi,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8375,PHI:6409,UniProt,I1RYH0,GenBank,CEF84198,,,PH-1,FgCdc11,chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,cell division control protein,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27387218,PubMed,10.1016/j.fgb.2016.07.005,Fungal Genet Biol. 2016 Sep;94:79-87,wangzh@fafu.edu.cn,"The loss of FgCdc3, FgCdc11, FgCdc12, but not FgCdc10, mutants showed significant reduction in growth, conidiation and virulence. Microscopic analyses revealed that all of them were involved in septum formation and nuclear division. Moreover, disruption of septin genes resulted in morphological defects in ascospores and conidia.",A Chen 2016,2016,4 genes,Chen-2016-Septins are involved in nuclear divi,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8376,PHI:6410,UniProt,I1RT81,GenBank,CEF84350,,,PH-1,FgCdc12,chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,cell division control protein,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27387218,PubMed,10.1016/j.fgb.2016.07.005,Fungal Genet Biol. 2016 Sep;94:79-87,wangzh@fafu.edu.cn,"The loss of FgCdc3, FgCdc11, FgCdc12, but not FgCdc10, mutants showed significant reduction in growth, conidiation and virulence. Microscopic analyses revealed that all of them were involved in septum formation and nuclear division. Moreover, disruption of septin genes resulted in morphological defects in ascospores and conidia.",A Chen 2016,2016,4 genes,Chen-2016-Septins are involved in nuclear divi,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8377,PHI:6411,UniProt,I1RPQ7,GenBank,CEF88384,,,PH-1,FgCdc10,chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,cell division control protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27387218,PubMed,10.1016/j.fgb.2016.07.005,Fungal Genet Biol. 2016 Sep;94:79-87,wangzh@fafu.edu.cn,"The loss of FgCdc3, FgCdc11, FgCdc12, but not FgCdc10, mutants showed significant reduction in growth, conidiation and virulence. Microscopic analyses revealed that all of them were involved in septum formation and nuclear division. Moreover, disruption of septin genes resulted in morphological defects in ascospores and conidia.",A Chen 2016,2016,4 genes,Chen-2016-Septins are involved in nuclear divi,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8378,PHI:6412,UniProt,A0A0L0VB04,GenBank,KNE96396,,,PST-78,PsSOD1,,,,,,,27350,Puccinia striiformis,,,yellow rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,superoxide dismutase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27399209,PubMed,10.1111/1462-2920.13451,Environ Microbiol. 2016 Jul 11,kangzs@nwsuaf.edu.cn,"Knockdown of PsSOD1 using a host-induced gene silencing (HIGS) system reduced the virulence of Pst, which was associated with ROS accumulation in HIGS plants.",J Liu 2016,2016,1 gene,Liu-2016-An extracellular Zn-only superoxide d,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8379,PHI:6413,UniProt,Q8Y557,GenBank,CAD00297,,,EGD-e,PrsA2,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen,peptidyl-prolyl cis/trans isomerase and chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26216425,PubMed,10.1128/IAI.00504-15,Infect Immun. 2015 Oct;83(10):4028-41,nfreitag@uic.edu,PrsA2 exhibits unique specificity for L. monocytogenes target proteins required for pathogenesis,L A Cahoon 2015,2015,1 gene,Cahoon-2015-Identification of conserved and sp,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8380,PHI:6415,UniProt,Q83FB9,GenBank,AAO89591,,,RSA 493,Cig2,,,,,,,777,Coxiella burnetii,227377,Nine Mile Phase I,Q fever,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,27435465,PubMed,10.1128/mBio.01127-16,MBio. 2016 Jul 19;7(4). pii: e01127-16,craig.roy@yale.edu,Cig2 enabled CCV homotypic fusion and enhanced bacterial virulence in the Galleria mellonella (wax moth) model of infection by a mechanism that decreases host tolerance.,L J Kohler 2016,2016,1 gene,Kohler-2016-Effector Protein Cig2 Decreases Ho,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8381,PHI:6416,UniProt,B7TQL9,GenBank,ACJ61294,,,2202,COR,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,coronatine (COR) biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27446113,PubMed,10.3389/fpls.2016.00880,Front Plant Sci. 2016 Jun 21;7:880,melotto@ucdavis.edu,The COR defective mutant Pst DC3118 is less effective in infecting Arabidopsis in the dark than under light and this difference in infection is reduced with the wild type bacterium Pst DC3000.,S Panchal 2016,2016,1 gene,Panchal-2016-Coronatine Facilitates Pseudomona,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8382,PHI:6417,UniProt,Q0R411,GenBank,AAZ80388,,,,Sm1,,,,,,,29875,Trichoderma virens,413071,Gv29-8,non-pathogenic: biocontrol,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Paymaster 2326 BG/RR,,,leaf,proteinaceous elicitor,,,,reduced virulence,,,,,,,,,,no,,,,,resistance,,functional test in host: transient expression,,,RP,16903350,PubMed,10.1094/MPMI-19-0838,Mol Plant Microbe Interact. 2006 Aug;19(8):838-53,c-kenerley@tamu.edu,Pretreatment of cotton cotyledons with Sm1 provided high levels of protection to the foliar pathogen Colletotrichum sp.,S Djonović 2006,2006,1 gene,"Djonovic-2006-Sm1, a proteinaceous elicitor se",BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8383,PHI:6417,UniProt,Q0R411,GenBank,AAZ80388,,,,Sm1,,,,,,,29875,Trichoderma virens,413071,Gv29-8,non-pathogenic: biocontrol,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Deltapine 50,,,leaf,proteinaceous elicitor,,,,reduced virulence,,,,,,,,,,no,,,,,resistance,,functional test in host: transient expression,,,RP,16903350,PubMed,10.1094/MPMI-19-0838,Mol Plant Microbe Interact. 2006 Aug;19(8):838-53,c-kenerley@tamu.edu,Pretreatment of cotton cotyledons with Sm1 provided high levels of protection to the foliar pathogen Colletotrichum sp.,S Djonović 2006,2006,1 gene,"Djonovic-2006-Sm1, a proteinaceous elicitor se",BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8384,PHI:6418,,no data found,,,,,,cmpA,,,,,,,446,Legionella pneumophila,,CR39,Legionnaires' disease; pneumonia,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,peptidoglycan-binding protein/OmpA-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27421957,PubMed,10.1093/femsle/fnw173,FEMS Microbiol Lett. 2016 Aug;363(16),shira.ninio@ocean.org.il,"The cmpA mutant displayed significant intracellular growth defects in both the protozoan host Acanthamoeba castellanii and in primary bone marrow-derived macrophages, where uptake into the cells was impaired.",I P Goodwin 2016,2016,1 gene,Goodwin-2016-A conserved OmpA-like protein in,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8385,PHI:6419,,no data found,BROAD,AFL2G_02624,,,NRRL3357,AflSkn7,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,stress response regulator,,,,reduced virulence,yes,,,,,reduced; aberrant,,reduced,,no,calcofluor white; congo red; NaCl; KCl; H2O2,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; NaCl: CHEBI:26710; H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion: full,,,RP,27399770,PubMed,10.3390/toxins8070202,Toxins (Basel). 2016 Jul 5;8(7),wshyyl@sina.com,"The deltaAflSkn7 mutants exhibited partially defective conidial formation and a complete inability to generate sclerotia, indicating AflSkn7 affects A. flavus asexual and sexual development.",F Zhang 2016,2016,1 gene,Zhang-2016-The Stress Response Regulator AflSk,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8386,PHI:6420,UniProt,P64036,GenBank,AAL23157,,,LT2,EF-P,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,elongation factor,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: downregulation,,,RP,27350030,PubMed,10.1111/mmi.13454,Mol Microbiol. 2016 Jun 28,eunjinlee@khu.ac.kr,Downregulation of EF-P selectively promotes expression of the virulence mgtC gene and contributes to Salmonella's ability to survive inside macrophages,D Nam 2016,2016,1 gene,Nam-2016-tRNAPro -mediated downregulation of e,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8387,PHI:6421,,no data found,GenBank,AAL21131,,,LT2,PbgA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,promotes their PhoPQ-regulated trafficking to the OM.,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,25856753,PubMed,10.1016/j.chom.2015.03.003,Cell Host Microbe. 2015 Apr 8;17(4):441-51,millersi@uw.edu,"PbgA globular region-deleted mutant bacteria are severely attenuated for pathogenesis, suggesting that increased cardiolipin trafficking to the OM is necessary for Salmonella to survive within host tissues that activate PhoPQ.",Z D Dalebroux 2015,2015,1 gene,Dalebroux-2015-Delivery of Cardiolipins to the,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8388,PHI:6422,UniProt,P9WI13,GenBank,CCP44553,,,H37Rv,PPE25,,,,,,,1772,Mycolicibacterium smegmatis,,,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,"Mycobacterium tuberculosis proline-proline-glutamic acid (PPE) family proteins, are members of the M. tuberculosis ESX-5 system associated with virulence of M. tuberculosis.",,,"NF-kB, ERK and p38 pathways",increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27351106,PubMed,10.1016/j.resmic.2016.06.004,Res Microbiol. 2016 Jun 25. pii: S0923-2508(16)30064-X,348865836@qq.com,Mycobacterium tuberculosis PPE25 and PPE26 enhance non-pathogenic M. smegmatis to survive in ANA-1 macrophages and persistence in mice,Y Mi 2016,2016,2 genes,Mi-2016-Mycobacterium tuberculosis PPE25 and P,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8389,PHI:6423,UniProt,Q79FK6,GenBank,AIR14538,,,H37Rv,PPE26,,,,,,,1772,Mycolicibacterium smegmatis,,,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,"Mycobacterium tuberculosis proline-proline-glutamic acid (PPE) family proteins, are members of the M. tuberculosis ESX-5 system associated with virulence of M. tuberculosis.",,,"NF-kB, ERK and p38 pathways",increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27351106,PubMed,10.1016/j.resmic.2016.06.004,Res Microbiol. 2016 Jun 25. pii: S0923-2508(16)30064-X,348865836@qq.com,Mycobacterium tuberculosis PPE25 and PPE26 enhance non-pathogenic M. smegmatis to survive in ANA-1 macrophages and persistence in mice,Y Mi 2016,2016,2 genes,Mi-2016-Mycobacterium tuberculosis PPE25 and P,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8390,PHI:6424,UniProt,H7C7N3,GenBank,AAF07416,,,B31,RevA,,,,,,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,outer ear; heart; bladder; skin,adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26150536,PubMed,10.1128/IAI.00530-15,Infect Immun. 2015 Sep;83(9):3675-83,catherine.brissette@med.und.edu,"The mutant was still infectious to mice, although it was significantly less well able to infect cardiac tissues. Complementation of the mutant with a wild-type revA gene restored heart infectivity to wild-type levels. Additionally, revA mutants led to increased evidence of arthritis, with increased fibrotic collagen deposition in tibiotarsal joints.",R Byram 2015,2015,1 gene,Byram-2015-Borrelia burgdorferi RevA significa,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8391,PHI:6425,UniProt,Q5NGC2,GenBank,AJI69237,,,SCHU S4,FTT_0924,,,,,,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25987704,PubMed,10.1128/IAI.00004-15,Infect Immun. 2015 Aug;83(8):3015-25,kawula@med.unc.edu,"The FTT_0924 mutant bacterial membrane is permeable when replicating in hypotonic solution and within macrophages, resulting in strongly reduced viability.",J Brunton 2015,2015,1 gene,Brunton-2015-Identifying Francisella tularensi,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8392,PHI:6426,UniProt,A0A0D1DP45,GenBank,KIS66229,,,521,Rss1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),,,,leaf,dual functions as putative SA receptor and transcriptional activator regulating genes important for SA and tryptophan degradation.,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27387604,PubMed,10.1111/mmi.13460,Mol Microbiol. 2016 Jul 8,armin.djamei@gmi.oeaw.ac.at,Dual functions as putative SA receptor and transcriptional activator regulating genes important for SA and tryptophan degradation.,F Rabe 2016,2016,1 gene,Rabe-2016-Phytohormone sensing in the biotroph,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8393,PHI:6427,UniProt,Q2FZ08,GenBank,BAF96735,,,,cvfA,,,,,,,1280,Staphylococcus aureus,,NCTC 8325-4,skin infection; food poisoning; respiratory disease,crickets,6999,Gryllus bimaculatus (related: two-spotted cricket),,,,,RNA modification enzyme regulating RNA degradation,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27377894,PubMed,10.1093/femsle/fnw163,FEMS Microbiol Lett. 2016 Aug;363(15). pii: fnw163,kaito@mol.f.u-tokyo.ac.jp,"Gryllus bimaculatus, which lives in tropical and subtropical regions, has been used as an animal model of human pathogenic bacterial infection.",Y Kochi 2016,2016,3 genes,Kochi-2016-A human pathogenic bacterial infect,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8394,PHI:6428,UniProt,P0A0I7,GenBank,AAA26597,,,,agr,,,,,,,1280,Staphylococcus aureus,,NCTC 8325-4,skin infection; food poisoning; respiratory disease,crickets,6999,Gryllus bimaculatus (related: two-spotted cricket),,,,,quorum sensing,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27377894,PubMed,10.1093/femsle/fnw163,FEMS Microbiol Lett. 2016 Aug;363(15). pii: fnw163,kaito@mol.f.u-tokyo.ac.jp,"Gryllus bimaculatus, which lives in tropical and subtropical regions, has been used as an animal model of human pathogenic bacterial infection.",Y Kochi 2016,2016,3 genes,Kochi-2016-A human pathogenic bacterial infect,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8395,PHI:6429,UniProt,Q2FV99,GenBank,AF162687_1,,,8325-4,SrtA,,,,,,,1280,Staphylococcus aureus,,NCTC 8325-4,skin infection; food poisoning; respiratory disease,crickets,6999,Gryllus bimaculatus (related: two-spotted cricket),,,,,anchoring cell wall proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27377894,PubMed,10.1093/femsle/fnw163,FEMS Microbiol Lett. 2016 Aug;363(15). pii: fnw163,kaito@mol.f.u-tokyo.ac.jp,"Gryllus bimaculatus, which lives in tropical and subtropical regions, has been used as an animal model of human pathogenic bacterial infection.",Y Kochi 2016,2016,3 genes,Kochi-2016-A human pathogenic bacterial infect,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8396,PHI:6430,UniProt,A0A0U0HH68,GenBank,COH07237,,,SMRU1216,PhtD,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung,zinc homeostasis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26573735,PubMed,10.1128/IAI.01082-15,Infect Immun. 2015 Nov 16;84(2):407-15,christopher.mcdevitt@adelaide.edu.au,"The combination of in vitro growth assays, active zinc uptake, and PhtD expression studies show that the His triad closest to the protein's amino terminus is the most important for zinc acquisition.",B A Eijkelkamp 2015,2015,1 gene,Eijkelkamp-2015-The first histidine triad moti,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8397,PHI:6431,UniProt,Q8PRN6,GenBank,AAM39226,,,306,PthA1,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,fruit,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence,"engineered binary constructs with 1 EBE, ProBs31EBE: GUSi or avrGf1, or 14 EBEs, ProBs314EBE: GUSi or avrGf1, carried in Agrobacterium",,RP,27362693,PubMed,10.1111/mpp.12454,Mol Plant Pathol. 2016 Jun 30,jbjones@ufl.edu,Transient assays show that activation of ProBs314EBE by X. citri TALEs is T3SS dependent and that expression of AvrGf1 triggers HR and correlates with reduced bacterial growth.,D Shantharaj 2016,2016,4 genes,Shantharaj-2016-An engineered promoter driving,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8398,PHI:6432,UniProt,Q8PRM3,GenBank,AAM39243,,,306,PthA2,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,fruit,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence,"engineered binary constructs with 1 EBE, ProBs31EBE: GUSi or avrGf1, or 14 EBEs, ProBs314EBE: GUSi or avrGf1, carried in Agrobacterium",,RP,27362693,PubMed,10.1111/mpp.12454,Mol Plant Pathol. 2016 Jun 30,jbjones@ufl.edu,Transient assays show that activation of ProBs314EBE by X. citri TALEs is T3SS dependent and that expression of AvrGf1 triggers HR and correlates with reduced bacterial growth.,D Shantharaj 2016,2016,4 genes,Shantharaj-2016-An engineered promoter driving,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8399,PHI:6433,UniProt,Q8PRK7,GenBank,AAM39261,,,306,PthA3,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,fruit,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence,"engineered binary constructs with 1 EBE, ProBs31EBE: GUSi or avrGf1, or 14 EBEs, ProBs314EBE: GUSi or avrGf1, carried in Agrobacterium",,RP,27362693,PubMed,10.1111/mpp.12454,Mol Plant Pathol. 2016 Jun 30,jbjones@ufl.edu,Transient assays show that activation of ProBs314EBE by X. citri TALEs is T3SS dependent and that expression of AvrGf1 triggers HR and correlates with reduced bacterial growth.,D Shantharaj 2016,2016,4 genes,Shantharaj-2016-An engineered promoter driving,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8400,PHI:6434,UniProt,Q8PRG7,GenBank,AAM39311,,,306,PthA4,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,fruit,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence,"engineered binary constructs with 1 EBE, ProBs31EBE: GUSi or avrGf1, or 14 EBEs, ProBs314EBE: GUSi or avrGf1, carried in Agrobacterium",,RP,27362693,PubMed,10.1111/mpp.12454,Mol Plant Pathol. 2016 Jun 30,jbjones@ufl.edu,Transient assays show that activation of ProBs314EBE by X. citri TALEs is T3SS dependent and that expression of AvrGf1 triggers HR and correlates with reduced bacterial growth.,D Shantharaj 2016,2016,4 genes,Shantharaj-2016-An engineered promoter driving,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8401,PHI:6431,UniProt,Q8PRN6,GenBank,AAM39226,,,306,PthA1,,,,,,PHI:6432; PHI:6433; PHI:6434,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,fruit,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence,"engineered binary constructs with 1 EBE, ProBs31EBE: GUSi or avrGf1, or 14 EBEs, ProBs314EBE: GUSi or avrGf1, carried in Agrobacterium",,RP,27362693,PubMed,10.1111/mpp.12454,Mol Plant Pathol. 2016 Jun 30,jbjones@ufl.edu,Transient assays show that activation of ProBs314EBE by X. citri TALEs is T3SS dependent and that expression of AvrGf1 triggers HR and correlates with reduced bacterial growth.,D Shantharaj 2016,2016,4 genes,Shantharaj-2016-An engineered promoter driving,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8402,PHI:6432,UniProt,Q8PRM3,GenBank,AAM39243,,,306,PthA2,,,,,,PHI:6431; PHI:6433; PHI:6434,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,fruit,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence,"engineered binary constructs with 1 EBE, ProBs31EBE: GUSi or avrGf1, or 14 EBEs, ProBs314EBE: GUSi or avrGf1, carried in Agrobacterium",,RP,27362693,PubMed,10.1111/mpp.12454,Mol Plant Pathol. 2016 Jun 30,jbjones@ufl.edu,Transient assays show that activation of ProBs314EBE by X. citri TALEs is T3SS dependent and that expression of AvrGf1 triggers HR and correlates with reduced bacterial growth.,D Shantharaj 2016,2016,4 genes,Shantharaj-2016-An engineered promoter driving,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8403,PHI:6433,UniProt,Q8PRK7,GenBank,AAM39261,,,306,PthA3,,,,,,PHI:6431; PHI:6432; PHI:6434,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,fruit,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence,"engineered binary constructs with 1 EBE, ProBs31EBE: GUSi or avrGf1, or 14 EBEs, ProBs314EBE: GUSi or avrGf1, carried in Agrobacterium",,RP,27362693,PubMed,10.1111/mpp.12454,Mol Plant Pathol. 2016 Jun 30,jbjones@ufl.edu,Transient assays show that activation of ProBs314EBE by X. citri TALEs is T3SS dependent and that expression of AvrGf1 triggers HR and correlates with reduced bacterial growth.,D Shantharaj 2016,2016,4 genes,Shantharaj-2016-An engineered promoter driving,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8404,PHI:6434,UniProt,Q8PRG7,GenBank,AAM39311,,,306,PthA4,,,,,,PHI:6431; PHI:6432; PHI:6433,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,fruit,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence,"engineered binary constructs with 1 EBE, ProBs31EBE: GUSi or avrGf1, or 14 EBEs, ProBs314EBE: GUSi or avrGf1, carried in Agrobacterium",,RP,27362693,PubMed,10.1111/mpp.12454,Mol Plant Pathol. 2016 Jun 30,jbjones@ufl.edu,Transient assays show that activation of ProBs314EBE by X. citri TALEs is T3SS dependent and that expression of AvrGf1 triggers HR and correlates with reduced bacterial growth.,D Shantharaj 2016,2016,4 genes,Shantharaj-2016-An engineered promoter driving,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8405,PHI:6435,UniProt,A1BYI4,GenBank,ABK00711,,,AH187,BaTdp,,,,,,,1392,Bacillus anthracis,,STI,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung; spleen; kidney,TIR domain protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27391310,PubMed,10.1371/journal.pone.0158575,PLoS One. 2016 Jul 8;11(7):e0158575,b.byrne@imperial.ac.uk,In vivo intra-nasal infection experiments in mice showed that a BaTdp knockout strain colonised host tissue faster with higher bacterial load within 4 days post-infection compared to the wild type B. anthracis.,E Carlsson 2016,2016,1 gene,Carlsson-2016-Bacillus anthracis TIR Domain-Co,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8406,PHI:6436,UniProt,A7EQ04,GenBank,EDO04920,,,1980 UF-70,Ss-Rhs1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27392818,PubMed,10.1111/mpp.12459,Mol Plant Pathol. 2016 Jul 9,yuyang2011@foxmail.com,Targeted silencing of Ss-Rhs1 resulted in abnormal colony morphology and reduced virulence on host plants.,Y Yu 2016,2016,1 gene,"Yu-2016-Ss-Rhs1, a secretory Rhs repeat-contai",BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8407,PHI:6436,UniProt,A7EQ04,GenBank,EDO04920,,,1980 UF-70,Ss-Rhs1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),cv. Zhongshuang 9,,,leaf,,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,RP,27392818,PubMed,10.1111/mpp.12459,Mol Plant Pathol. 2016 Jul 9,yuyang2011@foxmail.com,Targeted silencing of Ss-Rhs1 resulted in abnormal colony morphology and reduced virulence on host plants.,Y Yu 2016,2016,1 gene,"Yu-2016-Ss-Rhs1, a secretory Rhs repeat-contai",BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8408,PHI:6437,UniProt,Q87BY5,GenBank,AAO29160,,,Temecula1,PD1311,,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,leaf,acyl-CoA synthetase,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,H2O2; polymixin B,H2O2: CHEBI:16240; ;polymixin B: CHEBI:8310,,,,,gene mutation; gene complementation,,,RP,27388152,PubMed,10.1111/mpp.12428,Mol Plant Pathol. 2016 Jul 8,mowery@hws.edu,"It was determined that PD1311 is required for virulence, as the deletion mutant, deltaPD1311, was unable to cause disease on grapevines.",L Hao 2016,2016,1 gene,Hao-2016-Characterization of the Xylella fasti,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8409,PHI:6438,UniProt,Q59636,GenBank,AAC44154,,,8822,Ndk,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,host-responsive regulator/nucleoside diphosphate kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27345215,PubMed,10.1038/srep28684,Sci Rep. 2016 Jun 27;6:28684,zhangkebin12@163.com,In vivo studies demonstrated that the ndk mutant exhibits enhanced cytotoxicity and host pathogenicity by increasing T3SS proteins.,H Yu 2016,2016,1 gene,"Yu-2016-Ndk, a novel host-responsive regulator",BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8410,PHI:6439,UniProt,A0A060HKF7,GenBank,AIC13597,,,MUL0034,MqsRA,,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera,,,leaf,toxin-antitoxin system,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,27375608,PubMed,10.3389/fmicb.2016.00904,Front Microbiol. 2016 Jun 10;7:904,alessandra@centrodecitricultura.br,,M V Merfa 2016,2016,1 gene,Merfa-2016-The MqsRA Toxin-Antitoxin System fr,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8411,PHI:6440,,no data found,,,,,,pYV,,yscBL,,,,,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,rodents,10090,Mus musculus (related: house mouse),129S-Hfe<tm1.1Nca>/Auer; 129S-Hjv<tm1Nca>/Auer,,,spleen; liver,type III secretion system,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27446816,PubMed,10.3389/fcimb.2016.00069,Front Cell Infect Microbiol. 2016 Jun 24;6:69,vastone@ucsc.edu,"HH mice orally infected with Y. pseudotuberculosis lacking the T3SS-encoding virulence plasmid, pYV, displayed increased deep tissue colonization relative to wildtype mice.",H K Miller 2016,2016,1 gene,Miller-2016-Hereditary Hemochromatosis Predisp,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8412,PHI:6441,UniProt,Q4WDG8,GenBank,EAL85570,,,Af293,hisB,,,,,,,746128,Aspergillus fumigatus,,AfS77,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; cornea,histidine biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26854126,PubMed,10.1080/21505594.2016.1146848,Virulence. 2016 May 18;7(4):465-76,hubertus.haas@i-med.ac.at,"Deletion of the gene encoding imidazoleglycerol-phosphate dehydratase (HisB) in A. fumigatus causes (i) histidine auxotrophy, (ii) decreased resistance to both starvation and excess of various heavy metals, including iron, copper and zinc, which play a pivotal role in antimicrobial host defense, (iii) attenuation of pathogenicity in 4 virulence models: murine pulmonary infection, murine systemic infection, murine corneal infection, and wax moth larvae.",A Dietl 2016,2016,1 gene,Dietl-2016-Histidine biosynthesis plays a cruc,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8413,PHI:6441,UniProt,Q4WDG8,GenBank,EAL85570,,,Af293,hisB,,,,,,,746128,Aspergillus fumigatus,,AfS77,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histidine biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26854126,PubMed,10.1080/21505594.2016.1146848,Virulence. 2016 May 18;7(4):465-76,hubertus.haas@i-med.ac.at,"Deletion of the gene encoding imidazoleglycerol-phosphate dehydratase (HisB) in A. fumigatus causes (i) histidine auxotrophy, (ii) decreased resistance to both starvation and excess of various heavy metals, including iron, copper and zinc, which play a pivotal role in antimicrobial host defense, (iii) attenuation of pathogenicity in 4 virulence models: murine pulmonary infection, murine systemic infection, murine corneal infection, and wax moth larvae.",A Dietl 2016,2016,1 gene,Dietl-2016-Histidine biosynthesis plays a cruc,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8414,PHI:6442,UniProt,A0A023H5D8,GenBank,AFZ93918,,,CMS376,EepR,,,,,,,615,Serratia marcescens,,K904,keratitis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,cornea,part of putative two-component regulatory system/ response regulator transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26324535,PubMed,10.1128/IAI.00466-15,Infect Immun. 2015 Nov;83(11):4373-82,shanksrm@upmc.edu,,K M Brothers 2015,2015,1 gene,Brothers-2015-EepR mediates secreted protein p,BATCH_061,2016-09-01,MC,,,,,,,,,,,,,
,,Record 8415,PHI:6443,UniProt,Q4WK36,GenBank,EAL88096,,,Af293,hapC,,,,,,,746128,Aspergillus fumigatus,,A1160P+,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),OF1,,,liver; lung; kidney; spleen; brain,CCAAT-binding factor complex subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,27438727,PubMed,10.1371/journal.ppat.1005775,PLoS Pathog. 2016 Jul 20;12(7):e1005775,mike.bromley@manchester.ac.uk,Strains lacking a functional CBC are severely attenuated for pathogenicity in a pulmonary and systemic model of aspergillosis.,F Gsaller 2016,2016,1 gene,Gsaller-2016-Sterol Biosynthesis and Azole Tol,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8416,PHI:6444,UniProt,Q4X1B0,GenBank,EAL93355,,,Af293,Complex I NADH oxidoredutase,,,,,,,746128,Aspergillus fumigatus,,A1160P+,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,NADH-ubiquinone oxidoreductase 299 kDa subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27438017,PubMed,10.1371/journal.pone.0158724,PLoS One. 2016 Jul 20;11(7):e0158724,paul.bowyer@manchester.ac.uk,"Gene deletions of the 29.9KD subunit of this complex are azole resistant, less virulent and exhibit dysregulation of secondary metabolite gene clusters in a manner analogous to deletion mutants of the secondary metabolism regulator, LaeA.",M Bromley 2016,2016,1 gene,Bromley-2016-Mitochondrial Complex I Is a Glob,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8417,PHI:6445,UniProt,Q8Y1E6,GenBank,CAD14274,,,GMI1000,NucA,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,stem; root,extracellular DNase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation,,,RP,27387368,PubMed,10.1111/1462-2920.13446,Environ Microbiol. 2016 Jul 7,callen@wisc.edu,"This mutant was also reduced in virulence on tomato plants and did not spread in tomato stems as well as the wild-type strain, suggesting that these exDNases facilitate biofilm maturation and bacterial dispersal.",T M Tran 2016,2016,2 genes,Minh Tran-2016-Extracellular DNases of Ralston,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8418,PHI:6446,UniProt,Q8XWM2,GenBank,CAD16159,,,GMI1000,NucB,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,stem; root,extracellular DNase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation,,,RP,27387368,PubMed,10.1111/1462-2920.13446,Environ Microbiol. 2016 Jul 7,callen@wisc.edu,"This mutant was also reduced in virulence on tomato plants and did not spread in tomato stems as well as the wild-type strain, suggesting that these exDNases facilitate biofilm maturation and bacterial dispersal.",T M Tran 2016,2016,2 genes,Minh Tran-2016-Extracellular DNases of Ralston,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8419,PHI:6445,UniProt,Q8Y1E6,GenBank,CAD14274,,,GMI1000,NucA,,,,,,PHI:6446,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,stem; root,extracellular DNase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation,,,RP,27387368,PubMed,10.1111/1462-2920.13446,Environ Microbiol. 2016 Jul 7,callen@wisc.edu,"This mutant was also reduced in virulence on tomato plants and did not spread in tomato stems as well as the wild-type strain, suggesting that these exDNases facilitate biofilm maturation and bacterial dispersal.",T M Tran 2016,2016,2 genes,Minh Tran-2016-Extracellular DNases of Ralston,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8420,PHI:6446,UniProt,Q8XWM2,GenBank,CAD16159,,,GMI1000,NucB,,,,,,PHI:6445,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,stem; root,extracellular DNase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation,,,RP,27387368,PubMed,10.1111/1462-2920.13446,Environ Microbiol. 2016 Jul 7,callen@wisc.edu,"This mutant was also reduced in virulence on tomato plants and did not spread in tomato stems as well as the wild-type strain, suggesting that these exDNases facilitate biofilm maturation and bacterial dispersal.",T M Tran 2016,2016,2 genes,Minh Tran-2016-Extracellular DNases of Ralston,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8421,PHI:6447,UniProt,A0A164J6A6,GenBank,SAS94147,,,k553,rarA,,,,,,PHI:6448; PHI:6449; PHI:6450,573,Klebsiella pneumoniae,,NCTC 9633,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,Holliday junction DNA helicase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25193085,PubMed,10.1093/jac/dku340,J Antimicrob Chemother. 2015 Jan;70(1):81-8,mhn.chanoine@bjn.aphp.fr,"Whole-genome sequencing showed that KPBj1 Rev had lost the entire rarA-oqxABR locus, situated close to an integration hot spot of phage P4. This large deletion seemed responsible for the significantly lower virulence potential of strain KPBj1 Rev compared with KPBj1 E+. Moreover, we found that KPBj1 E+ DacrB was significantly less virulent than its parental strain.",S Bialek-Davenet 2014,2014,5 genes,Bialek-Davenet-2014-Differential contribution,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8422,PHI:6448,UniProt,U5U790,GenBank,AIS72928,,,324-FL,oqxA,,,,,,PHI:6447; PHI:6449; PHI:6450,573,Klebsiella pneumoniae,,NCTC 9633,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,RND family efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25193085,PubMed,10.1093/jac/dku340,J Antimicrob Chemother. 2015 Jan;70(1):81-8,mhn.chanoine@bjn.aphp.fr,"Whole-genome sequencing showed that KPBj1 Rev had lost the entire rarA-oqxABR locus, situated close to an integration hot spot of phage P4. This large deletion seemed responsible for the significantly lower virulence potential of strain KPBj1 Rev compared with KPBj1 E+. Moreover, we found that KPBj1 E+ DacrB was significantly less virulent than its parental strain.",S Bialek-Davenet 2014,2014,5 genes,Bialek-Davenet-2014-Differential contribution,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8423,PHI:6449,UniProt,W9B4Q6,GenBank,CDO12913,,,Kp52.145,oqxB,,,,,,PHI:6447; PHI:6448; PHI:6450,573,Klebsiella pneumoniae,,NCTC 9633,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,multidrug efflux pump,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25193085,PubMed,10.1093/jac/dku340,J Antimicrob Chemother. 2015 Jan;70(1):81-8,mhn.chanoine@bjn.aphp.fr,"Whole-genome sequencing showed that KPBj1 Rev had lost the entire rarA-oqxABR locus, situated close to an integration hot spot of phage P4. This large deletion seemed responsible for the significantly lower virulence potential of strain KPBj1 Rev compared with KPBj1 E+. Moreover, we found that KPBj1 E+ DacrB was significantly less virulent than its parental strain.",S Bialek-Davenet 2014,2014,5 genes,Bialek-Davenet-2014-Differential contribution,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8424,PHI:6450,,no data found,GenBank,CDI17948,,,SA1,oqxR,,,,,,PHI:6447; PHI:6448; PHI:6449,573,Klebsiella pneumoniae,,NCTC 9633,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,regulatory function,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25193085,PubMed,10.1093/jac/dku340,J Antimicrob Chemother. 2015 Jan;70(1):81-8,mhn.chanoine@bjn.aphp.fr,"Whole-genome sequencing showed that KPBj1 Rev had lost the entire rarA-oqxABR locus, situated close to an integration hot spot of phage P4. This large deletion seemed responsible for the significantly lower virulence potential of strain KPBj1 Rev compared with KPBj1 E+. Moreover, we found that KPBj1 E+ DacrB was significantly less virulent than its parental strain.",S Bialek-Davenet 2014,2014,5 genes,Bialek-Davenet-2014-Differential contribution,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8425,PHI:6451,UniProt,W9B4M6,GenBank,CDO13174,,,Kp52.145,acrB,,,,,,,573,Klebsiella pneumoniae,,NCTC 9633,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,acriflavine resistance protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25193085,PubMed,10.1093/jac/dku340,J Antimicrob Chemother. 2015 Jan;70(1):81-8,mhn.chanoine@bjn.aphp.fr,"Whole-genome sequencing showed that KPBj1 Rev had lost the entire rarA-oqxABR locus, situated close to an integration hot spot of phage P4. This large deletion seemed responsible for the significantly lower virulence potential of strain KPBj1 Rev compared with KPBj1 E+. Moreover, we found that KPBj1 E+ DacrB was significantly less virulent than its parental strain.",S Bialek-Davenet 2014,2014,5 genes,Bialek-Davenet-2014-Differential contribution,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8426,PHI:6452,UniProt,Q8F8P2,GenBank,AAN47712,,,56601,lpxD1,chromosome I,,,,,,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10045,Gerbillinae (related: gerbils),,,,liver; kidney,UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26283339,PubMed,10.1128/IAI.00897-15,Infect Immun. 2015 Nov;83(11):4314-21,mpicard@pasteur.fr,"Inactivation of only one of these genes, la0512/lpxD1, imparted sensitivity to the host physiological temperature (37°C) and rendered the bacteria avirulent in an animal infection model.",A Eshghi 2015,2015,2 genes,Eshghi-2015-Leptospira interrogans lpxD Homolo,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8427,PHI:6453,UniProt,Q8EY90,GenBank,AAN51524,,,56601,lpxD2,chromosome I,,,,,,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10045,Gerbillinae (related: gerbils),,,,liver; kidney,UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,26283339,PubMed,10.1128/IAI.00897-15,Infect Immun. 2015 Nov;83(11):4314-21,mpicard@pasteur.fr,"Inactivation of only one of these genes, la0512/lpxD1, imparted sensitivity to the host physiological temperature (37°C) and rendered the bacteria avirulent in an animal infection model.",A Eshghi 2015,2015,2 genes,Eshghi-2015-Leptospira interrogans lpxD Homolo,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8428,PHI:6454,UniProt,A7EPW1,GenBank,EDO04877,,,1980 UF-70,SsFKH1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,forkhead containing transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; KCl; H2O2,H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,altered gene expression / gene regulation: silencing,,,RP,27353472,PubMed,10.1111/mpp.12453,Mol Plant Pathol. 2016 Jun 29,panhongyu@jlu.edu.cn,Disease assays demonstrated that pathogenicity in RNAi-silenced strains was significantly compromised with the development of a smaller infection lesion on tomato leaves.,H Fan 2016,2016,1 gene,Fan-2016-An atypical forkhead containing trans,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8429,PHI:6455,UniProt,G4MTI8,GenBank,EHA54739,,,70-15,MoYcp4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,flavodoxin-like protein,,,,reduced virulence,,no,yes,yes,,increased,,reduced,,no,NaCl; KCl; H2O2; sodium dodecyl sulfate (SDS); calcofluor white (CFW); Congo red (CR),H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,RP,27377363,PubMed,10.1111/mpp.12455,Mol Plant Pathol. 2016 Jul 5,zhgzhang@njau.edu.cn,"MoYcp4, a target of MoAP1, is involved in the growth, conidiogenesis, and pathogenicity of M. oryzae.",Y Chen 2016,2016,1 gene,"Chen-2016-MoYcp4 is required for growth, conid",BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8430,PHI:6456,UniProt,B1MM63,GenBank,CAM64848,,,ATCC 19977,MAB_4780,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536,pulmonary disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,MaoC-like dehydratase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,RP,27385830,PubMed,10.1073/pnas.1605477113,Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4228-37,laurent.kremer@cpbs.cnrs.fr,MAB_4780 is required for Mabs to successfully establish acute and lethal infections.,I Halloum 2016,2016,1 gene,Halloum-2016-Deletion of a dehydratase importa,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8431,PHI:6460,UniProt,P07637,GenBank,AAA27028,,,,aroA,,,,,,PHI:6462; PHI:6463; PHI:6464,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,carboxyvinyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8432,PHI:6462,UniProt,P06179,GenBank,AAA27072,,,,fliC,,,,,,PHI:6460; PHI:6463; PHI:6464,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8433,PHI:6463,UniProt,P0A1K1,GenBank,AAA27102,,,,filj,,,,,,PHI:6460; PHI:6462; PHI:6464,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,flagellar protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8434,PHI:6464,UniProt,P0A1I3,GenBank,AAA16867,,,,invA,,,,,,PHI:6460; PHI:6462; PHI:6463,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,type III secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8435,PHI:6464,UniProt,P0A1I3,GenBank,AAA16867,,,,invA,,,,,,PHI:6462; PHI:6463,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,type III secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8436,PHI:6462,UniProt,P06179,GenBank,AAA27072,,,,fliC,,,,,,PHI:6464; PHI:6463,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8437,PHI:6463,UniProt,P0A1K1,GenBank,AAA27102,,,,filj,,,,,,PHI:6464; PHI:6462,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,flagellar protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8438,PHI:6461,UniProt,P04042,GenBank,AAL20833,,,LT2,cheB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,chemotaxis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8439,PHI:6462,UniProt,P06179,GenBank,AAA27072,,,,fliC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8440,PHI:6463,UniProt,P0A1K1,GenBank,AAA27102,,,,filj,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,flagellar protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8441,PHI:6464,UniProt,P0A1I3,GenBank,AAA16867,,,,invA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,type III secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27435462,PubMed,10.1128/mBio.00960-16,MBio. 2016 Jul 19;7(4). pii: e00960-16,ajbaumler@ucdavis.edu,"Tsr-mediated invasion of ileal Peyer's patches was abrogated in mice deficient for Nos2, the gene encoding iNOS.",F Rivera-Chávez 2016,2016,6 genes,Rivera-Chavez-2016-Energy Taxis toward Host-De,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8442,PHI:6466,UniProt,A0A0W0DKD7,GenBank,KTB12258,,,2A,Cgsiz1,,,,,,PHI:6467,5478,Candida glabrata,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver,E3 SUMO-protein ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27382059,PubMed,10.1074/jbc.M115.706044,J Biol Chem. 2016 Sep 9;291(37):19573-89,rkaur@cdfd.org.in,"Loss of the deSUMOylating enzyme CgUlp2 leads to highly reduced SUMO protein levels, and impaired growth, sensitivity to multiple stress conditions, reduced adherence to epithelial cells and poor colonization of specific tissues in mice.",R Gujjula 2016,2016,4 genes,Gujjula-2016-Identification of components of t,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8443,PHI:6467,UniProt,A0A0W0D9W9,GenBank,KTB01156,,,2A,Cgsiz2,,,,,,PHI:6466,5478,Candida glabrata,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver,E3 SUMO-protein ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27382059,PubMed,10.1074/jbc.M115.706044,J Biol Chem. 2016 Sep 9;291(37):19573-89,rkaur@cdfd.org.in,"Loss of the deSUMOylating enzyme CgUlp2 leads to highly reduced SUMO protein levels, and impaired growth, sensitivity to multiple stress conditions, reduced adherence to epithelial cells and poor colonization of specific tissues in mice.",R Gujjula 2016,2016,4 genes,Gujjula-2016-Identification of components of t,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8444,PHI:6468,UniProt,Q6FPN2,GenBank,CAG60761,,,CBS 138,Cgulp2,chromosome J,,,,,,5478,Candida glabrata,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver,deSUMOylation peptidase,,,,reduced virulence,,,,,,,,,,no,methyl methanesulfonate; hydrogen peroxide,methyl methanesulfonate: CHEBI:25255; H2O2: CHEBI:16240,,,,,gene mutation,,,RP,27382059,PubMed,10.1074/jbc.M115.706044,J Biol Chem. 2016 Sep 9;291(37):19573-89,rkaur@cdfd.org.in,"Loss of the deSUMOylating enzyme CgUlp2 leads to highly reduced SUMO protein levels, and impaired growth, sensitivity to multiple stress conditions, reduced adherence to epithelial cells and poor colonization of specific tissues in mice.",R Gujjula 2016,2016,4 genes,Gujjula-2016-Identification of components of t,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8445,PHI:6469,UniProt,A0A0W0C7W8,GenBank,KTA95678,,,2A,CgSmt3,,,,,,,5478,Candida glabrata,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver,ubiquitin-like protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,27382059,PubMed,10.1074/jbc.M115.706044,J Biol Chem. 2016 Sep 9;291(37):19573-89,rkaur@cdfd.org.in,"Loss of the deSUMOylating enzyme CgUlp2 leads to highly reduced SUMO protein levels, and impaired growth, sensitivity to multiple stress conditions, reduced adherence to epithelial cells and poor colonization of specific tissues in mice.",R Gujjula 2016,2016,4 genes,Gujjula-2016-Identification of components of t,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8446,PHI:6470,UniProt,J5K974,GenBank,EJP70691,,,ARSEF 2860,Trr1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,thioredoxin reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27344592,PubMed,10.1007/s00253-016-7688-0,Appl Microbiol Biotechnol. 2016 Jun 25,mgfeng@zju.edu.cn,,L Zhang 2016,2016,2 genes,Zhang-2016-Distinct roles of two cytoplasmic t,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8447,PHI:6471,UniProt,J4USC3,GenBank,EJP68552,,,ARSEF 2860,Trr2,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,thioredoxin reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27344592,PubMed,10.1007/s00253-016-7688-0,Appl Microbiol Biotechnol. 2016 Jun 25,mgfeng@zju.edu.cn,,L Zhang 2016,2016,2 genes,Zhang-2016-Distinct roles of two cytoplasmic t,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8448,PHI:6472,UniProt,P0A6Z3,GenBank,AAA23460,,,,htpG,,,,,,,562,Escherichia coli,,SP15,diarrhea,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,heat shock protein 90 chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27412582,PubMed,10.1093/infdis/jiw294,J Infect Dis. 2016 Sep 15;214(6):916-24.,patricia.martin@inserm.fr,Hsp90Ec molecular chaperone and the ClpQ protease involved in colibactin and yersiniabactin synthesis.,C Garcie 2016,2016,1 gene,Garcie-2016-The stress-responsive Hsp90 chaper,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8449,PHI:6472,UniProt,P0A6Z3,GenBank,AAA23460,,,,htpG,,,,,,,562,Escherichia coli,,SP15,diarrhea,rodents,10117,Rattus rattus (related: black rat),Wistar,,,,heat shock protein 90 chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27412582,PubMed,10.1093/infdis/jiw294,J Infect Dis. 2016 Sep 15;214(6):916-24.,patricia.martin@inserm.fr,Hsp90Ec molecular chaperone and the ClpQ protease involved in colibactin and yersiniabactin synthesis.,C Garcie 2016,2016,1 gene,Garcie-2016-The stress-responsive Hsp90 chaper,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8450,PHI:6473,UniProt,P9WKQ1,GenBank,CCP43636,,,H37Rv,Rv0888,,,,,,,1772,Mycolicibacterium smegmatis,,,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,extracellular nuclease,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant mutant proteins,,,RP,26742696,PubMed,10.1038/srep19033,Sci Rep. 2016 Jan 8;6:19033,siguo_liu@hvri.ac.cn,"In vivo infection studies confirmed that Rv0888 is required for infection and is related to pathogenicity, as the persistent ability of recombinant Mycobacterium smegmatis (rMS) Rv0888NS/MS and Rv0888S/MS is significantly higher than pMV262/MS in the lung tissue, and the Rv0888NS/MS and Rv0888S/MS could produce pathological changes in the mice lung.",G Dang 2016,2016,1 gene,"Dang-2016-Characterization of Rv0888, a Novel",BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8451,PHI:6474,UniProt,Q4WTS2,GenBank,EAL92004,,,Af293,cla4,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,"septin, AspB regulators",,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,,,,,,,gene deletion: full,,,RP,27446037,PubMed,10.3389/fmicb.2016.00997,Front Microbiol. 2016 Jun 22;7:997,bill.steinbach@duke.edu,"While deletion of gin4 resulted in larger interseptal distances and hypervirulence, a phenotype mimicking aspB deletion, deletion of cla4 and parA caused hyperseptation without impacting virulence, indicating divergent roles in regulating septation.",J M Vargas-Muñiz 2016,2016,3 genes,Vargas-Muniz-2016-Dephosphorylation of the Cor,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8452,PHI:6475,UniProt,Q4WEC9,GenBank,EAL86048,,,Af293,parA,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,"septin, AspB regulators",,,,unaffected pathogenicity,,,,,,reduced,,aberrant,,no,,,,,,,gene deletion: full,,,RP,27446037,PubMed,10.3389/fmicb.2016.00997,Front Microbiol. 2016 Jun 22;7:997,bill.steinbach@duke.edu,"While deletion of gin4 resulted in larger interseptal distances and hypervirulence, a phenotype mimicking aspB deletion, deletion of cla4 and parA caused hyperseptation without impacting virulence, indicating divergent roles in regulating septation.",J M Vargas-Muñiz 2016,2016,3 genes,Vargas-Muniz-2016-Dephosphorylation of the Cor,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8453,PHI:6476,UniProt,Q4WCS9,GenBank,EAL85809,,,Af293,gin4,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,"septin, AspB regulators",,,,reduced virulence,,,,,,reduced,,aberrant,,no,,,,,,,gene deletion: full,,,RP,27446037,PubMed,10.3389/fmicb.2016.00997,Front Microbiol. 2016 Jun 22;7:997,bill.steinbach@duke.edu,"While deletion of gin4 resulted in larger interseptal distances and hypervirulence, a phenotype mimicking aspB deletion, deletion of cla4 and parA caused hyperseptation without impacting virulence, indicating divergent roles in regulating septation.",J M Vargas-Muñiz 2016,2016,3 genes,Vargas-Muniz-2016-Dephosphorylation of the Cor,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8454,PHI:6477,UniProt,Q2G2U9,GenBank,BAB94445,,,MW2,sarA,,,,,,,1280,Staphylococcus aureus,,LAC,osteomyelitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,femur; bone,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27354444,PubMed,10.1128/IAI.00152-16,Infect Immun. 2016 Aug 19;84(9):2586-94,smeltzermarks@uams.edu,sarA is required for the production and/or accumulation of extracellular virulence factors that limit osteoblast and osteoclast viability and thereby promote bone destruction and reactive bone formation during the acute phase of S. aureus osteomyelitis.,A J Loughran 2016,2016,1 gene,Loughran-2016-Impact of sarA and phenol-solubl,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8455,PHI:6477,UniProt,Q2G2U9,GenBank,BAB94445,,,MW2,sarA,,,,,,,1280,Staphylococcus aureus,,UAMS-1,osteomyelitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,femur; bone,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27354444,PubMed,10.1128/IAI.00152-16,Infect Immun. 2016 Aug 19;84(9):2586-94,smeltzermarks@uams.edu,sarA is required for the production and/or accumulation of extracellular virulence factors that limit osteoblast and osteoclast viability and thereby promote bone destruction and reactive bone formation during the acute phase of S. aureus osteomyelitis.,A J Loughran 2016,2016,1 gene,Loughran-2016-Impact of sarA and phenol-solubl,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8456,PHI:6478,,no data found,GenBank,CAZ51393,,,SC84,fhs,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,formate tetrahydrofolate ligase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,27427088,PubMed,10.1016/j.micpath.2016.07.009,Microb Pathog. 2016 Sep;98:149-54,beiwc@mail.hzau.edu.cn,"Using murine and pig infection models, it was demonstrated that the formate-tetrahydrofolate ligase is required for the full virulence of S. suis 2.",C Zheng 2016,2016,1 gene,Zheng-2016-Formate-tetrahydrofolate ligase is,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8457,PHI:6478,,no data found,GenBank,CAZ51393,,,SC84,fhs,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,liver; spleen; lung; kidney; brain,formate tetrahydrofolate ligase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,27427088,PubMed,10.1016/j.micpath.2016.07.009,Microb Pathog. 2016 Sep;98:149-54,beiwc@mail.hzau.edu.cn,"Using murine and pig infection models, it was demonstrated that the formate-tetrahydrofolate ligase is required for the full virulence of S. suis 2.",C Zheng 2016,2016,1 gene,Zheng-2016-Formate-tetrahydrofolate ligase is,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8458,PHI:6479,UniProt,Q5A456,GenBank,EAK97511,,,SC5314,Pho4,,,,,,,5476,Candida albicans,,JC1936,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphate-responsive transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27385340,PubMed,10.1091/mbc.E16-05-0266,Mol Biol Cell. 2016 Sep 1;27(17):2784-801,janet.quinn@ncl.ac.uk,"C. albicans pho4delta cells are acutely sensitive to macrophage-mediated killing, and display attenuated virulence in animal infection models.",M A C Ikeh 2016,2016,1 gene,Ikeh-2016-Pho4 mediates phosphate acquisition,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8459,PHI:6480,UniProt,J9VIU5,GenBank,AFR94128,,,H99,LYS4,,,,,,,5207,Cryptococcus neoformans,,,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,mitochondrial homoaconitase,,,,reduced virulence,,,,,,,,,,no,congo red; sodium dodecyl sulfate (SDS); fluconazole; miconazole,"congo red: CHEBI:34653; SDS: CHEBI:8984; fluconazole: CHEBI:46081, CAS:86386-73-4; miconazole: CHEBI:6923",,,,,gene mutation; gene complementation,,,RP,27353379,PubMed,10.1016/j.bbrc.2016.06.123,Biochem Biophys Res Commun. 2016 Sep 2;477(4):706-11,whjung@cau.ac.kr,"lys4 mutant showed increased sensitivity to oxidative stress, agents that challenge cell wall/membrane integrity, and azole antifungal drugs. We showed that these phenotypes were due in part to impaired mitochondrial function as a result of LYS4 deletion, which we propose disrupts iron homeostasis in the organelle.",E Do 2016,2016,1 gene,Do-2016-The lysine biosynthetic enzyme Lys4 in,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8460,PHI:6481,UniProt,S9Q5R3,GenBank,EPX56639,,,DSM 2262,AvrRxo1,,,,,,,43,Cystobacter fuscus,1242864,DSMZ2262,water soaking,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27391081,PubMed,10.1371/journal.pone.0158856,PLoS One. 2016 Jul 8;11(7):e0158856,lindsay.triplett@ct.gov,"AvrRxo1 from C. fuscus caused watersoaking and triggered Rxo1-dependent cell collapse in Nicotiana benthamiana, but no growth suppression in E. coli was observed.",L R Triplett 2016,2016,1 gene,Triplett-2016-AvrRxo1 Is a Bifunctional Type I,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8461,PHI:6482,UniProt,Q8E0Q7,GenBank,AE014221_14,,,2603V/R,cylE,,,,,,,1311,Streptococcus agalactiae,,UPSA 807,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,urinary bladder,beta-hemolysin/cytolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,27383371,PubMed,10.1038/srep29000.,Sci Rep. 2016 Jul 7;6:29000,g.ulett@griffith.edu.au,"Severe UPSA 807-induced cytotoxicity was mediated entirely by the bacterial beta-hemolysin/cytolysin (beta-H/C) because an beta-H/C-deficient UPSA 807 isogenic mutant, UPSA 807deltacylE, was not cytotoxic in vitro; the mutant was also significantly attenuated for colonization in the bladder in vivo.",S Y Leclercq 2016,2016,1 gene,Leclercq-2016-Pathogenesis of Streptococcus ur,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8462,PHI:6483,UniProt,Q81J94,GenBank,AAP07156,,,ATCC 14579,Mfd,,,,,,,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,DNA repair,,,,loss of pathogenicity,,,,,,,,,,no,NO,NO: CHEBI:16480,,,,,gene disruption; gene complementation,,,RP,27435260,PubMed,10.1038/srep29349,Sci Rep. 2016 Jul 20;6:29349,nalini.ramarao@jouy.inra.f,"In vivo, the deltamfd mutant is avirulent and unable to survive the NO-stress.",E Guillemet 2016,2016,1 gene,Guillemet-2016-The bacterial DNA repair protei,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8463,PHI:6484,UniProt,Q9UVL6,GenBank,AF193508_1,,,1006,CRP1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,copper efflux pump,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27362522,PubMed,10.1371/journal.pone.0158683,PLoS One. 2016 Jun 30;11(6):e0158683,joanna.potrykus.mackie@gmail.com,,J Mackie 2016,2016,2 genes,Mackie-2016-Host-Imposed Copper Poisoning Impa,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8464,PHI:6485,UniProt,Q59NP1,GenBank,EAK92087,,,SC5314,CTR1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,copper importer,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27362522,PubMed,10.1371/journal.pone.0158683,PLoS One. 2016 Jun 30;11(6):e0158683,joanna.potrykus.mackie@gmail.com,,J Mackie 2016,2016,2 genes,Mackie-2016-Host-Imposed Copper Poisoning Impa,BATCH_061B,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8465,PHI:6486,UniProt,P9WN21,GenBank,CCP43852,,,H37Rv,GLPX,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,fructose bisphosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26258286,PubMed,10.1038/ncomms8912,Nat Commun. 2015 Aug 10;6:7912,sae2004@med.cornell.edu,Deletion of both GLPX and GPM2 is required for disruption of gluconeogenesis and attenuation of Mtb in a mouse model of infection.,U Ganapathy 2015,2015,2 genes,Ganapathy-2015-Two enzymes with redundant fruc,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8466,PHI:6486,UniProt,P9WN21,GenBank,CCP43852,,,H37Rv,GLPX,,,,,,PHI:6487,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,fructose bisphosphatase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26258286,PubMed,10.1038/ncomms8912,Nat Commun. 2015 Aug 10;6:7912,sae2004@med.cornell.edu,Deletion of both GLPX and GPM2 is required for disruption of gluconeogenesis and attenuation of Mtb in a mouse model of infection.,U Ganapathy 2015,2015,2 genes,Ganapathy-2015-Two enzymes with redundant fruc,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8467,PHI:6487,UniProt,P9WN21,GenBank,CCP43852,,,H37Rv,GPM2,,,,,,PHI:6486,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,fructose bisphosphatase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26258286,PubMed,10.1038/ncomms8912,Nat Commun. 2015 Aug 10;6:7912,sae2004@med.cornell.edu,Deletion of both GLPX and GPM2 is required for disruption of gluconeogenesis and attenuation of Mtb in a mouse model of infection.,U Ganapathy 2015,2015,2 genes,Ganapathy-2015-Two enzymes with redundant fruc,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8468,PHI:6488,,no data found,,,,,PSS7673,rsp,,,,,,,1280,Staphylococcus aureus,,BD02-25,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,"transcriptional regulator, AraC family",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26712209,PubMed,10.1128/IAI.01088-15,Infect Immun. 2015 Dec 28;84(3):723-34,ruth_limin@126.com,"Rsp was essential for the development of bacteremia and skin infection, representing major types of acute S. aureus infection.",T Li 2015,2015,1 gene,Li-2015-AraC-type regulator Rsp adapts Staphyl,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8469,PHI:6489,UniProt,Q8YC51,GenBank,AAL53923,,,16M,BveA,,,,,,,29459,Brucella melitensis,224914,16M,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lymph node,phospholipase A1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26282427,PubMed,10.1128/AAC.00792-15,Antimicrob Agents Chemother. 2015 Nov;59(11):6717-24,rmtsolis@ucdavis.edu,BveA was required for survival and replication of B. melitensis in macrophages and for persistent infection in mice. cervical lymph node,T Kerrinnes 2015,2015,1 gene,Kerrinnes-2015-A Phospholipase A1 modulates ce,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8470,PHI:6490,UniProt,J8SWL0,GenBank,EJS93632,,,CFBP 3304,trkH,,,,,,,55208,Pectobacterium wasabiae,,SCC3193,,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,Trk potassium transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26483524,PubMed,10.1128/JB.00569-15,J Bacteriol. 2015 Oct 19;198(2):248-55,kxavier@igc.gulbenkian.pt,"Regulation of rsmB expression by potassium via the Trk system occurred even in the absence of the GacS/GacA system, demonstrating that these systems act independently and are both required for full activation of RsmB and for the downstream induction of virulence in potato infection assays.",R S Valente 2015,2015,2 genes,Valente-2015-The Trk potassium transporter is,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8471,PHI:6491,UniProt,J8T0G0,GenBank,EJS95037,,,CFBP 3304,trkA,,,,,,,55208,Pectobacterium wasabiae,,SCC3193,,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,Trk potassium transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26483524,PubMed,10.1128/JB.00569-15,J Bacteriol. 2015 Oct 19;198(2):248-55,kxavier@igc.gulbenkian.pt,"Regulation of rsmB expression by potassium via the Trk system occurred even in the absence of the GacS/GacA system, demonstrating that these systems act independently and are both required for full activation of RsmB and for the downstream induction of virulence in potato infection assays.",R S Valente 2015,2015,2 genes,Valente-2015-The Trk potassium transporter is,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8472,PHI:6492,UniProt,V5VBJ6,GenBank,AKA30976,,,AB5075-UW,lipA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,spleen; liver,lipase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,26668261,PubMed,10.1128/JB.00622-15,J Bacteriol. 2015 Dec 14;198(4):711-9,mariasan@umich.edu,"Due to a lack of extracellular lipase, the gspD mutant, the gspE mutant, and a lipA deletion strain are incapable of growth on long-chain fatty acids as a sole source of carbon, while their growth characteristics are indistinguishable from those of the wild-type strain in nutrient-rich broth.",T L Johnson 2015,2015,2 genes,Johnson-2015-Acinetobacter baumannii is depend,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8473,PHI:6493,UniProt,A0A059ZUS1,GenBank,KCY48701,,,1571545,gspD,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,spleen; liver,type II secretion (T2S) system that is responsible for secretion of LipA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,RP,26668261,PubMed,10.1128/JB.00622-15,J Bacteriol. 2015 Dec 14;198(4):711-9,mariasan@umich.edu,"Due to a lack of extracellular lipase, the gspD mutant, the gspE mutant, and a lipA deletion strain are incapable of growth on long-chain fatty acids as a sole source of carbon, while their growth characteristics are indistinguishable from those of the wild-type strain in nutrient-rich broth.",T L Johnson 2015,2015,2 genes,Johnson-2015-Acinetobacter baumannii is depend,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8474,PHI:6494,UniProt,F9XMT4,Ensembl Genomes,Mycgr3G111221,,,IPO323,Mg3LysM,chromosome 11,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu80,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,LysM effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,RP,21467214,PubMed,10.1104/pp.111.176347,Plant Physiol. 2011 Jun;156(2):756-69,jason.rudd@bbsrc.ac.uk,"While Mg1LysM deletion mutant strains of M. graminicola were fully pathogenic toward wheat leaves, Mg3LysM mutant strains were severely impaired in leaf colonization, did not trigger lesion formation, and were unable to undergo asexual sporulation.",R Marshall 2011,2011,2 genes,Marshall-2011-Analysis of two in planta expres,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8475,PHI:6495,UniProt,F9XHX3,Ensembl Genomes,Mycgr3g105487,,,IPO323,Mg1LysM,chromosome 8,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu80,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,LysM effector,,,,effector (plant avirulence determinant),,,,,,reduced,,,,no,,,,,,,gene mutation,,,RP,21467214,PubMed,10.1104/pp.111.176347,Plant Physiol. 2011 Jun;156(2):756-69,jason.rudd@bbsrc.ac.uk,"While Mg1LysM deletion mutant strains of M. graminicola were fully pathogenic toward wheat leaves, Mg3LysM mutant strains were severely impaired in leaf colonization, did not trigger lesion formation, and were unable to undergo asexual sporulation.",R Marshall 2011,2011,2 genes,Marshall-2011-Analysis of two in planta expres,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8476,PHI:6496,UniProt,B2HHX0,GenBank,ACC43370,,,M,CpsA,,cpsA::Tn,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva; adult,bacterial cell wall integrity,,,,reduced virulence,,,,,,reduced,,aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,25939506,PubMed,10.1128/IAI.03081-14,Infect Immun. 2015 Jul;83(7):2844-54,qgao99@yahoo.com,The mutant shows impaired growth within macrophage cell lines and is severely attenuated in zebrafish larvae and adult zebrafish.,Q Wang 2015,2015,1 gene,"Wang-2015-CpsA, a LytR-CpsA-Psr Family Protein",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8477,PHI:6497,UniProt,D3VBH2,GenBank,CBJ89611,,,ATCC 19061,lrp,,,,,,,628,Xenorhabdus nematophila,,ATCC 19061,,moths,7130,Manduca sexta (related: tobacco hornworm),,,,larva,global transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,RP,26170407,PubMed,10.1128/JB.00272-15,J Bacteriol. 2015 Sep;197(18):3015-25,hgblair@bact.wisc.edu,"Cells expressing high levels of lrp were attenuated in these processes relative to those with low to intermediate lrp expression. Furthermore, fixed expression of lrp at high and low levels resulted in attenuated and normal virulence and immunosuppression, respectively, and eliminated population variability of these phenotypes.",E A Hussa 2015,2015,1 gene,Hussa-2015-The global transcription factor Lrp,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8478,PHI:6497,UniProt,D3VBH2,GenBank,CBJ89611,,,ATCC 19061,lrp,,,,,,,628,Xenorhabdus nematophila,,ATCC 19061,,moths,7130,Manduca sexta (related: tobacco hornworm),,,,larva,global transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,26170407,PubMed,10.1128/JB.00272-15,J Bacteriol. 2015 Sep;197(18):3015-25,hgblair@bact.wisc.edu,"Cells expressing high levels of lrp were attenuated in these processes relative to those with low to intermediate lrp expression. Furthermore, fixed expression of lrp at high and low levels resulted in attenuated and normal virulence and immunosuppression, respectively, and eliminated population variability of these phenotypes.",E A Hussa 2015,2015,1 gene,Hussa-2015-The global transcription factor Lrp,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8479,PHI:6498,,no data found,GenBank,AOW29912,,,SC5314,GRF10,,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,homeobox transcription factor-encoding gene,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene mutation,,,RP,26472755,PubMed,10.1093/femsyr/fov093,FEMS Yeast Res. 2015 Dec;15(8). pii: fov093,rolfesr@georgetown.edu,"Deletion of the GRF10 gene, in both C. albicans SN152 and BWP17 strain backgrounds, results in mutants with strongly decreased hyphal growth. The mutants are defective in chlamydospore and biofilm formation, as well as showing dramatically attenuated virulence in a mouse infection model.",A K Ghosh 2015,2015,1 gene,Ghosh-2015-The GRF10 homeobox gene regulates f,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8480,PHI:6498,,no data found,GenBank,AOW29912,,,SC5314,GRF10,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,homeobox transcription factor-encoding gene,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene mutation,,,RP,26472755,PubMed,10.1093/femsyr/fov093,FEMS Yeast Res. 2015 Dec;15(8). pii: fov093,rolfesr@georgetown.edu,"Deletion of the GRF10 gene, in both C. albicans SN152 and BWP17 strain backgrounds, results in mutants with strongly decreased hyphal growth. The mutants are defective in chlamydospore and biofilm formation, as well as showing dramatically attenuated virulence in a mouse infection model.",A K Ghosh 2015,2015,1 gene,Ghosh-2015-The GRF10 homeobox gene regulates f,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8481,PHI:6499,UniProt,P18177,GenBank,CAA37298,,,VPI 10463,TcdB,,,,,,,1496,Clostridioides difficile,,,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,toxin B,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26507679,PubMed,10.1093/femspd/ftv098,Pathog Dis. 2016 Feb;74(1):ftv098,hfeng@umaryland.edu,Lethal dose (LD100) of the most defective mutant (L1106K) showed no symptoms of disease highlighting the importance of this residue and the translocation domain in disease pathogenesis. Pathogen formerly called Clostridium difficile,T Hamza 2015,2015,1 gene,Hamza-2015-Defective Mutations within the Tran,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8482,PHI:6500,UniProt,C4B8B7,GenBank,BAH59485,,,Ina168,AVR-Pii,,none (wild-type),,,,,318829,Magnaporthe oryzae,,Ina168,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Hwayeongbye,Os-NADP-ME2 (wild-type),UniProt: Q9FRT2; GenBank: BAB20887; Ensembl: OS01G0723400,leaf,NADP-malic enzyme,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,resistance,none or very small reddish HR,other evidence: wild-type inoculation,,,RP; AC,27126515,PubMed,10.14348/molcells.2016.0094,Mol Cells. 2016 May 31;39(5):426-38,nsjwa@sejong.ac.kr,"M. oryzae attenuates the host ROS burst via AVR-Pii-mediated inhibition of Os-NADP-ME2, which is indispensable in ROS metabolism for the innate immunity of rice.",R Singh 2016,2016,1 gene,Singh-2016-Magnaporthe oryzae Effector AVR-Pii,BATCH_062/AC First host target curation,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8483,PHI:6500,UniProt,C4B8B7,GenBank,BAH59485,,,Ina168,AVR-Pii,,none (wild-type),,,,,318829,Magnaporthe oryzae,,Ina168,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Hwayeongbye,Os-NADP-ME2 (deletion mutant delta Os-nadp-me2-3),UniProt: Q9FRT2; GenBank: BAB20887; Ensembl: OS01G0723400,leaf,NADP-malic enzyme,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptible,brown spindle-shaped necrotic lesions,other evidence: host gene deletion,,,RP; AC,27126515,PubMed,10.14348/molcells.2016.0094,Mol Cells. 2016 May 31;39(5):426-38,nsjwa@sejong.ac.kr,"M. oryzae attenuates the host ROS burst via AVR-Pii-mediated inhibition of Os-NADP-ME2, which is indispensable in ROS metabolism for the innate immunity of rice.",R Singh 2016,2016,1 gene,Singh-2016-Magnaporthe oryzae Effector AVR-Pii,BATCH_062/AC First host target curation,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8484,PHI:6500,UniProt,C4B8B7,GenBank,BAH59485,,,Ina168,AVR-Pii,,none (wild-type),,,,,318829,Magnaporthe oryzae,,Ina168,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,Os-NADP-ME2 (assume wild-type),UniProt: Q9FRT2; GenBank: BAB20887; Ensembl: OS01G0723400,leaf,NADP-malic enzyme,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,susceptible,brown spindle-shaped necrotic lesions,other evidence: wild-type inoculation,,,RP; AC,27126515,PubMed,10.14348/molcells.2016.0094,Mol Cells. 2016 May 31;39(5):426-38,nsjwa@sejong.ac.kr,"M. oryzae attenuates the host ROS burst via AVR-Pii-mediated inhibition of Os-NADP-ME2, which is indispensable in ROS metabolism for the innate immunity of rice.",R Singh 2016,2016,1 gene,Singh-2016-Magnaporthe oryzae Effector AVR-Pii,BATCH_062/AC First host target curation,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8485,PHI:6500,UniProt,C4B8B7,GenBank,BAH59485,,,Ina168,AVR-Pii,,AVR-Pii (without signal peptide) bait in yeast two-hybrid,,,,,318829,Magnaporthe oryzae,,Ina168,blast (rice),monocots,4530,Oryza sativa (related: rice) (non-host bioassay: yeast),,,,,NADP-malic enzyme,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,Os-NADP-ME2-3 (prey rice cDNA library yeast two-hybrid),UniProt: Q9FRT2; GenBank: BAB20887; Ensembl: OS01G0723400,interacts in yeast two-hybrid,,other evidence: yeast two-hybrid,,,RP; AC,27126515,PubMed,10.14348/molcells.2016.0094,Mol Cells. 2016 May 31;39(5):426-38,nsjwa@sejong.ac.kr,"M. oryzae attenuates the host ROS burst via AVR-Pii-mediated inhibition of Os-NADP-ME2, which is indispensable in ROS metabolism for the innate immunity of rice.",R Singh 2016,2016,1 gene,Singh-2016-Magnaporthe oryzae Effector AVR-Pii,BATCH_062/AC First host target curation,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8486,PHI:6500,UniProt,C4B8B7,GenBank,BAH59485,,,Ina168,AVR-Pii,,AVR-Pii:pDEST-VYCE,,,,,318829,Magnaporthe oryzae,,Ina168,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf sheath,NADP-malic enzyme,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,Os-NADP-ME2-3:pDEST-VYNE,UniProt: Q9FRT2; GenBank: BAB20887; Ensembl: OS01G0723400,BiCF positive binding,,functional test in host: transient expression,"biolistic bombardment, confocal microscopy performed at 24h",,RP; AC,27126515,PubMed,10.14348/molcells.2016.0094,Mol Cells. 2016 May 31;39(5):426-38,nsjwa@sejong.ac.kr,"M. oryzae attenuates the host ROS burst via AVR-Pii-mediated inhibition of Os-NADP-ME2, which is indispensable in ROS metabolism for the innate immunity of rice.",R Singh 2016,2016,1 gene,Singh-2016-Magnaporthe oryzae Effector AVR-Pii,BATCH_062/AC First host target curation,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8487,PHI:6500,UniProt,C4B8B7,GenBank,BAH59485,,,Ina168,AVR-Pii,,35Sp:4xMyc:AVR-Pii (bait),,,,,318829,Magnaporthe oryzae,,Ina168,blast (rice),monocots,4530,Oryza sativa (related: rice) (non-host bioassay: tobacco),,,,leaf,NADP-malic enzyme,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,35Sp:3xHA:Os-NADP-ME2-3 (prey),UniProt: Q9FRT2; GenBank: BAB20887; Ensembl: OS01G0723400,positive co-IP,,functional test in host: transient expression,"Agrobacterium-mediated co-expression by infiltration into Nb, co-IP with anti-myc and immunoblot with anti-HA",,RP; AC,27126515,PubMed,10.14348/molcells.2016.0094,Mol Cells. 2016 May 31;39(5):426-38,nsjwa@sejong.ac.kr,"M. oryzae attenuates the host ROS burst via AVR-Pii-mediated inhibition of Os-NADP-ME2, which is indispensable in ROS metabolism for the innate immunity of rice.",R Singh 2016,2016,1 gene,Singh-2016-Magnaporthe oryzae Effector AVR-Pii,BATCH_062/AC First host target curation,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8488,PHI:6501,UniProt,A0A0H2ZQ21,GenBank,ABJ54846,,,D39,BglA3,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),MF1,,,lung; nasopharynx,6-phospho-Ɓ-glucosidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26527213,PubMed,10.1128/IAI.01108-15,Infect Immun. 2015 Nov 2;84(1):286-92,hy3@le.ac.uk,A mutated pneumococcal SPD0247 strain had reduced 6-phospho-glucosidase activity and was attenuated in growth on cellobiose and hyaluronic acid compared to the growth of wild-type D39.,V S Terra 2015,2015,1 gene,Terra-2015-Pneumococcal 6-phospho-beta-glucosi,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8489,PHI:6502,UniProt,Q8Y1X8,GenBank,CAD14089,,,GMI1000,PglLRs,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Platense,,,petiole; leaf,O-linked glycosylation,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26531228,PubMed,10.1093/glycob/cwv098.,Glycobiology. 2016 Mar;26(3):301-11,mariofeldman@wustl.edu,"Disruption of the O-OTase led to the total loss of protein glycosylation, together with a defect in biofilm formation and reduced pathogenicity towards tomato plants.",W Elhenawy 2015,2015,1 gene,Elhenawy-2015-Protein O-linked glycosylation i,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8490,PHI:6503,UniProt,Q1J773,GenBank,ABF37701,,,MGAS10750,fruR,,,,,,,1314,Streptococcus pyogenes,,5448,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,fructose metabolism,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26787724,PubMed,10.1128/IAI.01296-15,Infect Immun. 2016 Mar 24;84(4):1016-31,kmciver@umd.edu,"The ability of both fruR and fruB mutants to survive in the presence of whole human blood or neutrophils was impaired, the phenotype was not reproduced in murine whole blood, and those mutants were not attenuated in a mouse intraperitoneal infection.",K M Valdes 2016,2016,2 genes,Valdes-2016-The fruRBA operon is necessary for,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8491,PHI:6504,UniProt,J7M380,GenBank,BAM30054,,,M1 476,fruB,,,,,,,1314,Streptococcus pyogenes,,5448,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,fructose metabolism,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26787724,PubMed,10.1128/IAI.01296-15,Infect Immun. 2016 Mar 24;84(4):1016-31,kmciver@umd.edu,"The ability of both fruR and fruB mutants to survive in the presence of whole human blood or neutrophils was impaired, the phenotype was not reproduced in murine whole blood, and those mutants were not attenuated in a mouse intraperitoneal infection.",K M Valdes 2016,2016,2 genes,Valdes-2016-The fruRBA operon is necessary for,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8492,PHI:6505,UniProt,Q0P7J0,GenBank,CAJ76300,,,IHE3034,clbA,,deltaclbA::kan,,,,,562,Escherichia coli,,A192PP,neonatal meningitis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,intestine; colon; blood; mesenteric lymph node; liver; kidney; spleen,colibactin genotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26150540,PubMed,10.1128/IAI.00716-15,Infect Immun. 2015 Sep;83(9):3704-11,peter.taylor@ucl.ac.uk,"Inactivation of clbA and clbP in E. coli A192PP, a virulent strain of serotype O18:K1 that colonizes the gastrointestinal tract and translocates to the blood compartment with very high frequency in experimental infection of the neonatal rat, significantly reduced the capacity of A192PP to colonize the gut, engender double-strand breaks in DNA, and cause invasive, lethal disease.",A J McCarthy 2016,2016,2 genes,McCarthy-2015-The Genotoxin Colibactin is a De,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8493,PHI:6506,UniProt,Q0P7K6,GenBank,CAJ76284,,,IHE3034,clbP,,deltaclbP::kan,,,,,562,Escherichia coli,,A192PP,neonatal meningitis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,intestine; colon; blood; mesenteric lymph node; liver; kidney; spleen,colibactin genotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26150540,PubMed,10.1128/IAI.00716-15,Infect Immun. 2015 Sep;83(9):3704-11,peter.taylor@ucl.ac.uk,"Inactivation of clbA and clbP in E. coli A192PP, a virulent strain of serotype O18:K1 that colonizes the gastrointestinal tract and translocates to the blood compartment with very high frequency in experimental infection of the neonatal rat, significantly reduced the capacity of A192PP to colonize the gut, engender double-strand breaks in DNA, and cause invasive, lethal disease.",A J McCarthy 2016,2016,2 genes,McCarthy-2015-The Genotoxin Colibactin is a De,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8494,PHI:6507,UniProt,A0A0H2UX24,GenBank,AAM79974,,,MGAS315,LiaS,,LiaSR135G,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,muscle; nasopharynx,sensor kinase,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene mutation,,,RP,26283331,PubMed,10.1128/IAI.00656-15,Infect Immun. 2015 Nov;83(11):4237-46,arflores@bcm.edu,The carrier mutation also resulted in a reduced ability to grow in human blood and reduced virulence in a mouse model of necrotizing fasciitis. Repair of the mutation in the GAS carrier strain restored virulence,A R Flores 2015,2015,1 gene,Flores-2015-A single amino acid replacement in,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8495,PHI:6508,UniProt,P0A1G5,GenBank,AAD01437,,,F98,DksA,,pWSK29::dksA (Ampr),,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestine; liver; spleen,response regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,RP,26553464,PubMed,10.1128/IAI.01135-15,Infect Immun. 2015 Nov 9;84(1):375-84,ohad.Gal-Mor@sheba.health.gov.il,"Using the colitis mouse model, we found that dksA is spatially induced at the midcecum during the early stage of the infection and required for gastrointestinal colonization and systemic infection in vivo.",S Azriel 2015,2015,1 gene,Azriel-2015-The Stringent Response Regulator D,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8496,PHI:6509,UniProt,Q9A121,GenBank,AAK33510,,,M1 GAS,gloA,,5448deltagloA,,,,,1314,Streptococcus pyogenes,,5448,infection,rodents,10090,Mus musculus (related: house mouse),AlbPLG1<+/->,,,,glyoxylase I (S-lactoylglutathione lyase),,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26702634,PubMed,10.1093/femspd/ftv122,Pathog Dis. 2016 Mar;74(2). pii: ftv122,y.ong@uq.edu.au,5448 gloA was more sensitive to methylglyoxal and was also more susceptible to human neutrophil killing.,M M Zhang 2015,2015,1 gene,Zhang-2015-Defence against methylglyoxal in Gr,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8497,PHI:6510,UniProt,Q8Y8N0,GenBank,CAC98944,,,EGD-e,CshA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,RNA helicase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26483402,PubMed,10.1128/IAI.00849-15,Infect Immun. 2015 Oct 19;84(1):67-76,jorgen.johansson@molbiol.umu.se,"Although the expression of several virulence factors was reduced, the cshA strain did not demonstrate any reduced ability to infect nonphagocytic cells compared to the wild-type strain.",S Netterling 2015,2015,1 gene,Netterling-2015-An RNA-helicase important for,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8498,PHI:6510,UniProt,Q8Y8N0,GenBank,CAC98944,,,EGD-e,CshA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,RNA helicase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26483402,PubMed,10.1128/IAI.00849-15,Infect Immun. 2015 Oct 19;84(1):67-76,jorgen.johansson@molbiol.umu.se,"Although the expression of several virulence factors was reduced, the cshA strain did not demonstrate any reduced ability to infect nonphagocytic cells compared to the wild-type strain.",S Netterling 2015,2015,1 gene,Netterling-2015-An RNA-helicase important for,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8499,PHI:6511,UniProt,B0LF89,GenBank,ABW24960,,,3091,fimK,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,pilus regulatory gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26347570,PubMed,10.1093/infdis/jiv440,J Infect Dis. 2016 Feb 15;213(4):649-58,rosen_d@kids.wustl.edu,"Loss of fimK in TOP52 pneumonia was associated with diminished lung bacterial burden, limited innate responses within the lung, and improved host survival.",D A Rosen 2015,2015,1 gene,Rosen-2015-Klebsiella pneumoniae FimK Promotes,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8500,PHI:6512,UniProt,A0A171JTK6,GenBank,GAF01387,,,36-25-1,lplA1,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,colon; mesenteric lymph node ; spleen; liver,lipoate protein ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26015479,PubMed,10.1128/IAI.00503-15,Infect Immun. 2015 Aug;83(8):3146-56,sarah.dorazio@uky.edu,"Lipoate protein ligase-deficient L. monocytogenes (lplA1) mutants, which display impaired intracellular growth, were able to colonize the colon but did not persist efficiently and had a significant defect in spreading to the MLN, spleen, and liver.",G S Jones 2015,2015,1 gene,Jones-2015-Intracellular Listeria monocytogene,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8501,PHI:6512,UniProt,A0A171JTK6,GenBank,GAF01387,,,36-25-1,lplA1,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/cByJ,,,colon; mesenteric lymph node ; spleen; liver,lipoate protein ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26015479,PubMed,10.1128/IAI.00503-15,Infect Immun. 2015 Aug;83(8):3146-56,sarah.dorazio@uky.edu,"Lipoate protein ligase-deficient L. monocytogenes (lplA1) mutants, which display impaired intracellular growth, were able to colonize the colon but did not persist efficiently and had a significant defect in spreading to the MLN, spleen, and liver.",G S Jones 2015,2015,1 gene,Jones-2015-Intracellular Listeria monocytogene,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8502,PHI:6513,UniProt,A5IYC8,GenBank,GAF01387,,,36-25-1,MAG3390,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,lymph node; mammary gland,lipoyltransferase and lipoate-protein ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25916984,PubMed,10.1128/IAI.00403-15,Infect Immun. 2015 Jul;83(7):2751-61,Rohini.Chopra-Dewasthaly@vetmeduni.ac.at,"Seven mutants with insertions in genes MAG1050, MAG2540, MAG3390, uhpT, eutD, adhT, and MAG4460 were not recovered from any of the infected animals.",S Hegde 2015,2015,7 genes,Hegde-2015-Simultaneous Identification of Pote,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8503,PHI:6514,UniProt,A5IYN5,GenBank,CAL59144,,,PG2,MAG4460,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,lymph node; mammary gland,haloacid dehalogenase-like hydrolases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25916984,PubMed,10.1128/IAI.00403-15,Infect Immun. 2015 Jul;83(7):2751-61,Rohini.Chopra-Dewasthaly@vetmeduni.ac.at,"Seven mutants with insertions in genes MAG1050, MAG2540, MAG3390, uhpT, eutD, adhT, and MAG4460 were not recovered from any of the infected animals.",S Hegde 2015,2015,7 genes,Hegde-2015-Simultaneous Identification of Pote,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8504,PHI:6515,UniProt,A5IYT6,GenBank,CAL59195,,,PG2,uhpT,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,lymph node; mammary gland,hexosephosphate transport protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25916984,PubMed,10.1128/IAI.00403-15,Infect Immun. 2015 Jul;83(7):2751-61,Rohini.Chopra-Dewasthaly@vetmeduni.ac.at,"Seven mutants with insertions in genes MAG1050, MAG2540, MAG3390, uhpT, eutD, adhT, and MAG4460 were not recovered from any of the infected animals.",S Hegde 2015,2015,7 genes,Hegde-2015-Simultaneous Identification of Pote,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8505,PHI:6516,UniProt,D3VPS7,GenBank,WP_013021801,,,,eutD,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,lymph node; mammary gland,phosphate acetyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25916984,PubMed,10.1128/IAI.00403-15,Infect Immun. 2015 Jul;83(7):2751-61,Rohini.Chopra-Dewasthaly@vetmeduni.ac.at,"Seven mutants with insertions in genes MAG1050, MAG2540, MAG3390, uhpT, eutD, adhT, and MAG4460 were not recovered from any of the infected animals.",S Hegde 2015,2015,7 genes,Hegde-2015-Simultaneous Identification of Pote,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8506,PHI:6517,UniProt,A5IYL7,GenBank,CAL59126,,,PG2,adhT,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,lymph node; mammary gland,alcohol dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25916984,PubMed,10.1128/IAI.00403-15,Infect Immun. 2015 Jul;83(7):2751-61,Rohini.Chopra-Dewasthaly@vetmeduni.ac.at,"Seven mutants with insertions in genes MAG1050, MAG2540, MAG3390, uhpT, eutD, adhT, and MAG4460 were not recovered from any of the infected animals.",S Hegde 2015,2015,7 genes,Hegde-2015-Simultaneous Identification of Pote,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8507,PHI:6518,UniProt,A5IXP4,GenBank,CAL58803,,,PG2,MAG1050,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,lymph node; mammary gland,predicted lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25916984,PubMed,10.1128/IAI.00403-15,Infect Immun. 2015 Jul;83(7):2751-61,Rohini.Chopra-Dewasthaly@vetmeduni.ac.at,"Seven mutants with insertions in genes MAG1050, MAG2540, MAG3390, uhpT, eutD, adhT, and MAG4460 were not recovered from any of the infected animals.",S Hegde 2015,2015,7 genes,Hegde-2015-Simultaneous Identification of Pote,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8508,PHI:6519,UniProt,A5IY43,GenBank,CAL58952,,,PG2,MAG2540,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,lymph node; mammary gland,Vpma like predicted lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25916984,PubMed,10.1128/IAI.00403-15,Infect Immun. 2015 Jul;83(7):2751-61,Rohini.Chopra-Dewasthaly@vetmeduni.ac.at,"Seven mutants with insertions in genes MAG1050, MAG2540, MAG3390, uhpT, eutD, adhT, and MAG4460 were not recovered from any of the infected animals.",S Hegde 2015,2015,7 genes,Hegde-2015-Simultaneous Identification of Pote,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8509,PHI:6520,UniProt,Q5ZVD8,GenBank,AAU27584,,,Philadelphia 1,LpdA,,,,,,,446,Legionella pneumophila,866628,130b,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26216420,PubMed,10.1128/IAI.00785-15,Infect Immun. 2015 Oct;83(10):3989-4002,g.frankel@imperial.ac.uk,"L. pneumophila lpdA mutant displayed reduced replication in murine lungs, suggesting that it is a virulence factor contributing to L. pneumophila infection in vivo.",G N Schroeder 2015,2015,1 gene,Schroeder-2015-The Legionella pneumophila effe,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8510,PHI:6521,,no data found,GenBank,AMP61195,,,UW8175,Fnm,,TX82 fnm; an fnm markerless deletion mutant,,,,,1352,Enterococcus faecium,749520,TX82,endocarditis,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,heart,fibronectin-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26371130,PubMed,10.1128/IAI.00885-15,Infect Immun. 2015 Dec;83(12):4653-61,bem.asst@uth.tmc.edu,"Deletion of fnm resulted in a significant reduction in the ability of the mutant, TX6128, to bind fibronectin relative to that of the wild-type strain; in situ reconstitution of fnm in the deletion mutant strain restored adherence. In addition, the fnm mutant was highly attenuated relative to TX82 (P < 0.0001) in a mixed-inoculum rat endocarditis model.",S R Somarajan 2015,2015,1 gene,Somarajan-2015-The Fibronectin-binding Protein,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8511,PHI:6522,UniProt,O51590,GenBank,AAC66998,,,B31,ptsG,,,,,,,139,Borreliella burgdorferi,,5A18NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeNHsd,,,skin; heart; joint; bladder,"Pts system, iibc components",,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26712207,PubMed,10.1128/IAI.00917-15,Infect Immun. 2015 Dec 28;84(3):754-64,Bijay.K.Khajanchi@uth.tmc.edu,The PEP-PTS glucose transporter PtsG appears to play important roles in the pathogenesis of B. burgdorferi that extend beyond its transport functions.,B K Khajanchi 2015,2015,8 genes,Khajanchi-2015-Phosphoenolpyruvate Phosphotran,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8512,PHI:6523,UniProt,A0A0H3C2N0,GenBank,ACK74817,,,ZS7,cyaB,,,,,,,139,Borreliella burgdorferi,,5A18NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeNHsd,,,skin; heart; joint; bladder,adenylyl cyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26712207,PubMed,10.1128/IAI.00917-15,Infect Immun. 2015 Dec 28;84(3):754-64,Bijay.K.Khajanchi@uth.tmc.edu,The PEP-PTS glucose transporter PtsG appears to play important roles in the pathogenesis of B. burgdorferi that extend beyond its transport functions.,B K Khajanchi 2015,2015,8 genes,Khajanchi-2015-Phosphoenolpyruvate Phosphotran,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8513,PHI:6524,UniProt,O51369,GenBank,AAC66787,,,B31,fruA1,,,,,,,139,Borreliella burgdorferi,,5A18NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeNHsd,,,skin; heart; joint; bladder,"Pts system, fructose-specific iiabc component",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26712207,PubMed,10.1128/IAI.00917-15,Infect Immun. 2015 Dec 28;84(3):754-64,Bijay.K.Khajanchi@uth.tmc.edu,The PEP-PTS glucose transporter PtsG appears to play important roles in the pathogenesis of B. burgdorferi that extend beyond its transport functions.,B K Khajanchi 2015,2015,8 genes,Khajanchi-2015-Phosphoenolpyruvate Phosphotran,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8514,PHI:6525,UniProt,O51143,GenBank,AAC66516,,,WI91-23,malX1,,,,,,,139,Borreliella burgdorferi,,5A18NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeNHsd,,,skin; heart; joint; bladder,"Pts system, maltose and glucose-specific iiabc component",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26712207,PubMed,10.1128/IAI.00917-15,Infect Immun. 2015 Dec 28;84(3):754-64,Bijay.K.Khajanchi@uth.tmc.edu,The PEP-PTS glucose transporter PtsG appears to play important roles in the pathogenesis of B. burgdorferi that extend beyond its transport functions.,B K Khajanchi 2015,2015,8 genes,Khajanchi-2015-Phosphoenolpyruvate Phosphotran,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8515,PHI:6526,UniProt,O51000,GenBank,AAC66326,,,B31,malX2,,,,,,,139,Borreliella burgdorferi,,5A18NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeNHsd,,,skin; heart; joint; bladder,PTS system maltose and glucose-specific transporter subunit IIABC,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26712207,PubMed,10.1128/IAI.00917-15,Infect Immun. 2015 Dec 28;84(3):754-64,Bijay.K.Khajanchi@uth.tmc.edu,The PEP-PTS glucose transporter PtsG appears to play important roles in the pathogenesis of B. burgdorferi that extend beyond its transport functions.,B K Khajanchi 2015,2015,8 genes,Khajanchi-2015-Phosphoenolpyruvate Phosphotran,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8516,PHI:6527,UniProt,O51575,GenBank,AAC66983,,,B31,fruK,,,,,,,139,Borreliella burgdorferi,,5A18NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeNHsd,,,skin; heart; joint; bladder,phosphofructokinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26712207,PubMed,10.1128/IAI.00917-15,Infect Immun. 2015 Dec 28;84(3):754-64,Bijay.K.Khajanchi@uth.tmc.edu,The PEP-PTS glucose transporter PtsG appears to play important roles in the pathogenesis of B. burgdorferi that extend beyond its transport functions.,B K Khajanchi 2015,2015,8 genes,Khajanchi-2015-Phosphoenolpyruvate Phosphotran,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8517,PHI:6528,UniProt,O50981,GenBank,AAC66323,,,297,chbA,,,,,,,139,Borreliella burgdorferi,,5A18NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeNHsd,,,skin; heart; joint; bladder,phosphotransferase enzyme II,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26712207,PubMed,10.1128/IAI.00917-15,Infect Immun. 2015 Dec 28;84(3):754-64,Bijay.K.Khajanchi@uth.tmc.edu,The PEP-PTS glucose transporter PtsG appears to play important roles in the pathogenesis of B. burgdorferi that extend beyond its transport functions.,B K Khajanchi 2015,2015,8 genes,Khajanchi-2015-Phosphoenolpyruvate Phosphotran,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8518,PHI:6529,UniProt,O50980,GenBank,AAC66324,,,,chbC,,,,,,,139,Borreliella burgdorferi,,5A18NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeNHsd,,,skin; heart; joint; bladder,PTS chitobiose transporter subunit IIA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26712207,PubMed,10.1128/IAI.00917-15,Infect Immun. 2015 Dec 28;84(3):754-64,Bijay.K.Khajanchi@uth.tmc.edu,The PEP-PTS glucose transporter PtsG appears to play important roles in the pathogenesis of B. burgdorferi that extend beyond its transport functions.,B K Khajanchi 2015,2015,8 genes,Khajanchi-2015-Phosphoenolpyruvate Phosphotran,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8519,PHI:6530,UniProt,X0I5S4,GenBank,EXL79446,,,54008,gas1,,,,,,,5507,Fusarium oxysporum,100902,f. sp. conglutinans,wilt,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage) cv. Zhong Gan 21,,,seedling; leaf,glucanosyltransferase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,26333982,PubMed,10.1038/srep13663,Sci Rep. 2015 Sep 3;5:13663,lrfcaas@gmail.com,Foc-deltagas1 significantly reduced growth rate and virulence compared with wild type isolates.,E Li 2015,2015,1 gene,Li-2015-Comparative Proteomics Analyses of Two,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8520,PHI:6531,UniProt,Q849X5,GenBank,AAO49613,,,,HlyF,,,,,,,562,Escherichia coli,475609,serotype O78:K80:H9 strain χ7122,colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,blood,hemolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26494774,PubMed,10.1093/infdis/jiv506,J Infect Dis. 2016 Mar 1;213(5):856-65,eric.oswald@inserm.fr,The increased production of OMVs was associated with the release of toxins. hlyF was shown to be expressed during extraintestinal infection and to play a role in the virulence of extraintestinal pathogenic E. coli in a chicken model of colibacillosis.,K Murase 2015,2015,1 gene,Murase-2015-Hlyf Produced By Extraintestinal P,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8521,PHI:6532,UniProt,P0A9Q1,GenBank,AAA97297,,,MG1655,arcA,,,,motA; motB; cheA,"motA, UniProt: P09348; motB:, UniProt: P0AF06; cheA, UniProt: P07363",,562,Escherichia coli,,XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,brain,aerobic respiration control protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26099584,PubMed,10.1128/IAI.00312-15,Infect Immun. 2015 Sep;83(9):3545-54,liganwu@iastate.edu,"ArcA controls metabolism, chemotaxis, and motility contributing to the pathogenicity of APEC.",F Jiang 2015,2015,5 genes,"Jiang-2015-ArcA Controls Metabolism, Chemotaxi",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8522,PHI:6533,UniProt,P09348,GenBank,AAA24177,,,,motA,,,,arcA,UniProt: P0A9Q1,,562,Escherichia coli,,XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,brain,motility protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26099584,PubMed,10.1128/IAI.00312-15,Infect Immun. 2015 Sep;83(9):3545-54,liganwu@iastate.edu,"Deletion of flagellar genes motA and motB and chemotaxis gene cheA significantly attenuated the virulence of APEC, and ArcA was shown to directly regulate the expression of motA, motB, and cheA.",F Jiang 2015,2015,5 genes,"Jiang-2015-ArcA Controls Metabolism, Chemotaxi",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8523,PHI:6534,UniProt,P0AF06,GenBank,AAA24178,,,,motB,,,,arcA,UniProt: P0A9Q1,,562,Escherichia coli,,XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,brain,motility protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26099584,PubMed,10.1128/IAI.00312-15,Infect Immun. 2015 Sep;83(9):3545-54,liganwu@iastate.edu,"Deletion of flagellar genes motA and motB and chemotaxis gene cheA significantly attenuated the virulence of APEC, and ArcA was shown to directly regulate the expression of motA, motB, and cheA.",F Jiang 2015,2015,5 genes,"Jiang-2015-ArcA Controls Metabolism, Chemotaxi",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8524,PHI:6535,UniProt,P07363,GenBank,AAA23573,,,,cheA,,,,arcA,UniProt: P0A9Q1,,562,Escherichia coli,,XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,brain,chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26099584,PubMed,10.1128/IAI.00312-15,Infect Immun. 2015 Sep;83(9):3545-54,liganwu@iastate.edu,"Deletion of flagellar genes motA and motB and chemotaxis gene cheA significantly attenuated the virulence of APEC, and ArcA was shown to directly regulate the expression of motA, motB, and cheA.",F Jiang 2015,2015,5 genes,"Jiang-2015-ArcA Controls Metabolism, Chemotaxi",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8525,PHI:6536,UniProt,P0A964,GenBank,AAA23565,,,,cheW,,,,,,PHI:6535,562,Escherichia coli,,XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,brain,chemotaxis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26099584,PubMed,10.1128/IAI.00312-15,Infect Immun. 2015 Sep;83(9):3545-54,liganwu@iastate.edu,The mutant with a double deletion of cheA and cheW was as virulent as the wild type.,F Jiang 2015,2015,5 genes,"Jiang-2015-ArcA Controls Metabolism, Chemotaxi",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8526,PHI:6535,UniProt,P07363,GenBank,AAA23573,,,,cheA,,,,arcA,UniProt: P0A9Q1,PHI:6536,562,Escherichia coli,,XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,brain,chemotaxis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26099584,PubMed,10.1128/IAI.00312-15,Infect Immun. 2015 Sep;83(9):3545-54,liganwu@iastate.edu,The mutant with a double deletion of cheA and cheW was as virulent as the wild type.,F Jiang 2015,2015,5 genes,"Jiang-2015-ArcA Controls Metabolism, Chemotaxi",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8527,PHI:6537,UniProt,Q8Y619,GenBank,CAC99961,,,EGD-e,ChiA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,chitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25908871,PubMed,10.1093/femsle/fnv067,FEMS Microbiol Lett. 2015 May;362(10). pii: fnv067,jjl@sund.ku.dk,"The Salmonella chitinase did not contribute significantly to infection of D. discoideum, mammalian cell lines or mice. However, survival in D. discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold).",R F Frederiksen 2015,2015,3 genes,Frederiksen-2015-Effects of Listeria monocytog,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8528,PHI:6538,UniProt,Q8YAL3,GenBank,CAC98320,,,EGD-e,ChiB,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,chitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25908871,PubMed,10.1093/femsle/fnv067,FEMS Microbiol Lett. 2015 May;362(10). pii: fnv067,jjl@sund.ku.dk,"The Salmonella chitinase did not contribute significantly to infection of D. discoideum, mammalian cell lines or mice. However, survival in D. discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold).",R F Frederiksen 2015,2015,3 genes,Frederiksen-2015-Effects of Listeria monocytog,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8529,PHI:6537,UniProt,Q8Y619,GenBank,CAC99961,,,EGD-e,ChiA,,,,,,PHI:6538,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,chitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25908871,PubMed,10.1093/femsle/fnv067,FEMS Microbiol Lett. 2015 May;362(10). pii: fnv067,jjl@sund.ku.dk,"The Salmonella chitinase did not contribute significantly to infection of D. discoideum, mammalian cell lines or mice. However, survival in D. discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold).",R F Frederiksen 2015,2015,3 genes,Frederiksen-2015-Effects of Listeria monocytog,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8530,PHI:6538,UniProt,Q8YAL3,GenBank,CAC98320,,,EGD-e,ChiB,,,,,,PHI:6537,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,chitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25908871,PubMed,10.1093/femsle/fnv067,FEMS Microbiol Lett. 2015 May;362(10). pii: fnv067,jjl@sund.ku.dk,"The Salmonella chitinase did not contribute significantly to infection of D. discoideum, mammalian cell lines or mice. However, survival in D. discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold).",R F Frederiksen 2015,2015,3 genes,Frederiksen-2015-Effects of Listeria monocytog,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8531,PHI:6539,UniProt,Q8ZS09,GenBank,AAL18982,,,LT2,ChiA,,,,,,,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,chitinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25908871,PubMed,10.1093/femsle/fnv067,FEMS Microbiol Lett. 2015 May;362(10). pii: fnv067,jjl@sund.ku.dk,"The Salmonella chitinase did not contribute significantly to infection of D. discoideum, mammalian cell lines or mice. However, survival in D. discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold).",R F Frederiksen 2015,2015,3 genes,Frederiksen-2015-Effects of Listeria monocytog,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8532,PHI:6537,UniProt,Q8Y619,GenBank,CAC99961,,,EGD-e,ChiA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),,,,,chitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25908871,PubMed,10.1093/femsle/fnv067,FEMS Microbiol Lett. 2015 May;362(10). pii: fnv067,jjl@sund.ku.dk,"The Salmonella chitinase did not contribute significantly to infection of D. discoideum, mammalian cell lines or mice. However, survival in D. discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold).",R F Frederiksen 2015,2015,3 genes,Frederiksen-2015-Effects of Listeria monocytog,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8533,PHI:6538,UniProt,Q8YAL3,GenBank,CAC98320,,,EGD-e,ChiB,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),,,,,chitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25908871,PubMed,10.1093/femsle/fnv067,FEMS Microbiol Lett. 2015 May;362(10). pii: fnv067,jjl@sund.ku.dk,"The Salmonella chitinase did not contribute significantly to infection of D. discoideum, mammalian cell lines or mice. However, survival in D. discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold).",R F Frederiksen 2015,2015,3 genes,Frederiksen-2015-Effects of Listeria monocytog,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8534,PHI:6537,UniProt,Q8Y619,GenBank,CAC99961,,,EGD-e,ChiA,,,,,,PHI:6538,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),,,,,chitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25908871,PubMed,10.1093/femsle/fnv067,FEMS Microbiol Lett. 2015 May;362(10). pii: fnv067,jjl@sund.ku.dk,"The Salmonella chitinase did not contribute significantly to infection of D. discoideum, mammalian cell lines or mice. However, survival in D. discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold).",R F Frederiksen 2015,2015,3 genes,Frederiksen-2015-Effects of Listeria monocytog,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8535,PHI:6538,UniProt,Q8YAL3,GenBank,CAC98320,,,EGD-e,ChiB,,,,,,PHI:6537,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),,,,,chitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25908871,PubMed,10.1093/femsle/fnv067,FEMS Microbiol Lett. 2015 May;362(10). pii: fnv067,jjl@sund.ku.dk,"The Salmonella chitinase did not contribute significantly to infection of D. discoideum, mammalian cell lines or mice. However, survival in D. discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold).",R F Frederiksen 2015,2015,3 genes,Frederiksen-2015-Effects of Listeria monocytog,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8536,PHI:6539,UniProt,Q8ZS09,GenBank,AAL18982,,,LT2,ChiA,,,,,,,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,salmonellosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),,,,,chitinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,25908871,PubMed,10.1093/femsle/fnv067,FEMS Microbiol Lett. 2015 May;362(10). pii: fnv067,jjl@sund.ku.dk,"The Salmonella chitinase did not contribute significantly to infection of D. discoideum, mammalian cell lines or mice. However, survival in D. discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold).",R F Frederiksen 2015,2015,3 genes,Frederiksen-2015-Effects of Listeria monocytog,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8537,PHI:6540,UniProt,Q5K7J5,GenBank,AAW46754,,,JEC21,ALL2,chromosome 13,,,,,,5207,Cryptococcus neoformans,,RC2,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,regulating pH homeostasis,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26597983,PubMed,10.1128/IAI.01046-15,Infect Immun. 2015 Nov 23;84(2):439-51,bettina.fries@stonybrookmedicine.edu,,N Jain 2015,2015,2 genes,"Jain-2015-ALL2, a homologue of ALL1, contribut",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8538,PHI:6541,UniProt,J9VW33,GenBank,AFR98448,,,H99,ALL1,chromosome 12,,,,,PHI:6540,5207,Cryptococcus neoformans,,RC2,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,iron homeostasis,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26597983,PubMed,10.1128/IAI.01046-15,Infect Immun. 2015 Nov 23;84(2):439-51,bettina.fries@stonybrookmedicine.edu,,N Jain 2015,2015,2 genes,"Jain-2015-ALL2, a homologue of ALL1, contribut",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8539,PHI:6541,UniProt,J9VW33,GenBank,AFR98448,,,H99,ALL1,chromosome 12,,,,,PHI:6540,5207,Cryptococcus neoformans,,RC2,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,iron homeostasis,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26597983,PubMed,10.1128/IAI.01046-15,Infect Immun. 2015 Nov 23;84(2):439-51,bettina.fries@stonybrookmedicine.edu,,N Jain 2015,2015,2 genes,"Jain-2015-ALL2, a homologue of ALL1, contribut",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8540,PHI:6540,UniProt,Q5K7J5,GenBank,AAW46754,,,JEC21,ALL2,chromosome 13,,,,,PHI:6541,5207,Cryptococcus neoformans,,RC2,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,regulating pH homeostasis,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,RP,26597983,PubMed,10.1128/IAI.01046-15,Infect Immun. 2015 Nov 23;84(2):439-51,bettina.fries@stonybrookmedicine.edu,,N Jain 2015,2015,2 genes,"Jain-2015-ALL2, a homologue of ALL1, contribut",BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8541,PHI:6542,UniProt,Q4QSS2,GenBank,AAY20981,,,25RS84,mga,,,,,,,1314,Streptococcus pyogenes,798300,MGAS15252,infection,rodents,10090,Mus musculus (related: house mouse),immunocompetent SKH1-hrBR hairless,,,skin,multiple gene regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25476528,PubMed,10.1016/j.ajpath.2014.10.018,Am J Pathol. 2015 Feb;185(2):462-71,rjolsen@houstonmethodist.org,"Compared to the wild-type strain, a H201R isogenic mutant strain caused significantly larger skin lesions in mice / The isogenic H201R strain was significantly more virulent in a nonhuman primate model of joint infection.",M Sanson 2014,2014,1 gene,Sanson-2014-A Naturally Occurring Single Amino,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8542,PHI:6542,UniProt,Q4QSS2,GenBank,AAY20981,,,25RS84,mga,,,,,,,1314,Streptococcus pyogenes,798300,MGAS15252,infection,primates,9541,Macaca fascicularis (related: crab-eating macaque),,,,joint,multiple gene regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,25476528,PubMed,10.1016/j.ajpath.2014.10.018,Am J Pathol. 2015 Feb;185(2):462-71,rjolsen@houstonmethodist.org,"Compared to the wild-type strain, a H201R isogenic mutant strain caused significantly larger skin lesions in mice / The isogenic H201R strain was significantly more virulent in a nonhuman primate model of joint infection.",M Sanson 2014,2014,1 gene,Sanson-2014-A Naturally Occurring Single Amino,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8543,PHI:6543,UniProt,Q9L7R4,GenBank,AF220438_7,,,LT2,yihO,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,O-antigen capsule,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26195553,PubMed,10.1128/IAI.00634-15,Infect Immun. 2015 Oct;83(10):3946-59,gunn.43@osu.edu,,J M Marshall 2015,2015,3 genes,Marshall-2015-The O-antigen capsule of Salmone,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8544,PHI:6544,UniProt,A0A0F6B9I4,GenBank,ACY91186,,,14028S,yshA,,,,,,PHI:6545,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,O-antigen capsule,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26195553,PubMed,10.1128/IAI.00634-15,Infect Immun. 2015 Oct;83(10):3946-59,gunn.43@osu.edu,,J M Marshall 2015,2015,3 genes,Marshall-2015-The O-antigen capsule of Salmone,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8545,PHI:6545,UniProt,Q9L7R1,GenBank,AF220439_2,,,LT2,yihW,,,,,,PHI:6544,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,O-antigen capsule,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26195553,PubMed,10.1128/IAI.00634-15,Infect Immun. 2015 Oct;83(10):3946-59,gunn.43@osu.edu,,J M Marshall 2015,2015,3 genes,Marshall-2015-The O-antigen capsule of Salmone,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8546,PHI:6546,UniProt,F9XB78,Ensembl Genomes,Mycgr3G80707,,,,Zt80707,Chr_5:0657996-0658613,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Obelisk,,,leaf,involved in virulence and host-specific disease development,,,,reduced virulence,,,,,,reduced; aberrant,,,,no,NaCl; H2O2; Congo red; calcofluor,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene mutation; gene complementation,,,RP,26225424,PubMed,10.1371/journal.ppat.1005055,PLoS Pathog. 2015 Jul 30;11(7):e1005055,estukenbrock@bot.uni-kiel.de,,S Poppe 2015,2015,3 genes,Poppe-2015-Rapidly Evolving Genes Are Key Play,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8547,PHI:6547,UniProt,F9X3Q1,Ensembl Genomes,Mycgr3G103264,,,,Zt103264,Chr_2:1992714-1993521,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Obelisk,,,leaf,involved in virulence and host-specific disease development,,,,reduced virulence,,,,,,reduced; aberrant,,,,no,NaCl; H2O2; Congo red; calcofluor,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene mutation; gene complementation,,,RP,26225424,PubMed,10.1371/journal.ppat.1005055,PLoS Pathog. 2015 Jul 30;11(7):e1005055,estukenbrock@bot.uni-kiel.de,,S Poppe 2015,2015,3 genes,Poppe-2015-Rapidly Evolving Genes Are Key Play,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8548,PHI:6548,UniProt,F9WZ47,Ensembl Genomes,Mycgr3G89160,,,,Zt89160,Chr_1:2089079-2090359,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Obelisk,,,leaf,involved in virulence and host-specific disease development,,,,increased virulence (hypervirulence),,,,,,wild type,,,,no,NaCl; H2O2; Congo red; calcofluor,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene mutation; gene complementation,,,RP,26225424,PubMed,10.1371/journal.ppat.1005055,PLoS Pathog. 2015 Jul 30;11(7):e1005055,estukenbrock@bot.uni-kiel.de,,S Poppe 2015,2015,3 genes,Poppe-2015-Rapidly Evolving Genes Are Key Play,BATCH_062,2016-10-01,MC,,,,,,,,,,,,,
,,Record 8549,PHI:6549,UniProt,A0A0H5ASD5,GenBank,BAR92624,,,,PblB,,,,,,,1313,Streptococcus pneumoniae,,4496,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,platelet-binding protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,26755156,PubMed,10.1128/IAI.01454-15,Infect Immun. 2016 Jan 11;84(3):822-32,james.paton@adelaide.edu.au,,R M Harvey 2016,2016,2 genes,Harvey-2016-The Variable Region of the Pneumoc,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8550,PHI:6550,,no data found,,,,,2842STDY5753564,PPI1,,,,,,,1313,Streptococcus pneumoniae,,4496,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,pathogenicity island,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,26755156,PubMed,10.1128/IAI.01454-15,Infect Immun. 2016 Jan 11;84(3):822-32,james.paton@adelaide.edu.au,vPPI1 pneumococcal pathogenicity island 1 (27Kb),R M Harvey 2016,2016,2 genes,Harvey-2016-The Variable Region of the Pneumoc,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8551,PHI:6551,UniProt,Q4TVQ0,,,,,,prfA,,constitutively active prfA* containing a G145S mutation,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),B6;129X1-Mpeg1<tm1Pod>/Pod,Perforin-2 (Mpeg1),UniProt: A1L314; GenBank: AAI29844,liver; spleen,virulence factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,26831467,PubMed,10.1128/IAI.01434-15,Infect Immun. 2016 Mar 24;84(4):1083-91,kschesser@med.miami.edu,"Perforin-2 +/+ wildtype mice or Perforin-2 -/- siRNA knockdown, both exhibit increased virulence with overexpressing PrfA* strain. Perforin restricts the proliferation of the intracytosolic pathogen Listeria monocytogenes.",R McCormack 2016,2016,1 gene,McCormack-2016-Perforin-2 Protects Host Cells,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8552,PHI:6552,UniProt,A3P6Z6,GenBank,ABN93279,,,1106a,BipC,chromosome II,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25165162,PubMed,10.1093/infdis/jiu492,J Infect Dis. 2015 Mar 1;211(5):827-34,jamuna@ummc.edu.my,"The virulence of the mutant strain in a murine model of melioidosis demonstrated that the bipC mutant was less virulent, compared with the wild type.",W Kang 2014,2014,1 gene,Kang-2014-Functional characterizations of effe,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8553,PHI:6553,UniProt,Q54001,GenBank,TOLC_SALEN,,,,MdsABC,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,multidrug transporter of Salmonella,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26283336,PubMed,10.1128/IAI.00653-15,Infect Immun. 2015 Nov;83(11):4266-76,ykim@cu.ac.kr,"Salmonella infection of macrophages induced the upregulation of MdsABC expression and led to an increase of intracellular bacterial number and host cell death, similar to the effects of MdsABC overexpression and PSPS pretreatment on the mdsABC deletion strain.",S Song 2015,2015,1 gene,Song-2015-An MdsABC-Mediated Pathway for Patho,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8554,PHI:6554,UniProt,Q4WJR9,GenBank,EAL88213,,,Af293,sB,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,sulfate transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26787716,PubMed,10.1128/IAI.01124-15,Infect Immun. 2016 Mar 24;84(4):917-29,sven.krappmann@uk-erlangen.de,,J Amich 2016,2016,4 genes,Amich-2016-Exploring sulfur assimilation of As,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8555,PHI:6555,UniProt,Q4WZV9,GenBank,EAL93856,,,Af293,sF,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,sulfite reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26787716,PubMed,10.1128/IAI.01124-15,Infect Immun. 2016 Mar 24;84(4):917-29,sven.krappmann@uk-erlangen.de,,J Amich 2016,2016,4 genes,Amich-2016-Exploring sulfur assimilation of As,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8556,PHI:6556,UniProt,Q4X256,GenBank,EAL93059,,,Af293,mecA,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,cystathionine-beta-synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26787716,PubMed,10.1128/IAI.01124-15,Infect Immun. 2016 Mar 24;84(4):917-29,sven.krappmann@uk-erlangen.de,,J Amich 2016,2016,4 genes,Amich-2016-Exploring sulfur assimilation of As,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8557,PHI:6557,UniProt,Q4W9S1,GenBank,XP_746580,,,Af293,cysB,,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,cysteine synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26787716,PubMed,10.1128/IAI.01124-15,Infect Immun. 2016 Mar 24;84(4):917-29,sven.krappmann@uk-erlangen.de,,J Amich 2016,2016,4 genes,Amich-2016-Exploring sulfur assimilation of As,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8558,PHI:6556,UniProt,Q4X256,GenBank,EAL93059,,,Af293,mecA,,,,,,PHI:6557,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,cystathionine-beta-synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26787716,PubMed,10.1128/IAI.01124-15,Infect Immun. 2016 Mar 24;84(4):917-29,sven.krappmann@uk-erlangen.de,,J Amich 2016,2016,4 genes,Amich-2016-Exploring sulfur assimilation of As,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8559,PHI:6557,UniProt,Q4W9S1,GenBank,XP_746580,,,Af293,cysB,,,,,,PHI:6556,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,cysteine synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,RP,26787716,PubMed,10.1128/IAI.01124-15,Infect Immun. 2016 Mar 24;84(4):917-29,sven.krappmann@uk-erlangen.de,,J Amich 2016,2016,4 genes,Amich-2016-Exploring sulfur assimilation of As,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8560,PHI:6558,UniProt,B2RHH4,GenBank,BAG32819,,,ATCC 33277,omp17,,,,,,,837,Porphyromonas gingivalis,242619,W83,periodontitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,gingipain production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26502912,PubMed,10.1128/IAI.01308-15,Infect Immun. 2015 Oct 26;84(1):230-40,oharan@md.okayama-u.ac.jp,A mutant lacking Omp17 did not show pigmentation on blood agar and showed reduced proteolytic activity of the gingipains.,Y Taguchi 2015,2015,1 gene,Taguchi-2015-Involvement of an Skp-like protei,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8561,PHI:6560,UniProt,Q5KM96,GenBank,AAW41864,,,JEC21,mid1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,high-affinity calcium channel,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene mutation,,,RP,26385891,PubMed,10.1128/EC.00100-15,Eukaryot Cell. 2015 Nov;14(11):1135-43,acgelli@ucdavis.edu,,K Vu 2015,2015,2 genes,Vu-2015-The Cch1-Mid1 high-affinity calcium ch,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8562,PHI:6561,UniProt,Q1HHN2,GenBank,ABF46942,,,H99,Cch1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,high-affinity calcium channel,,,,reduced virulence,,,,,,,,,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene mutation,,,RP,26385891,PubMed,10.1128/EC.00100-15,Eukaryot Cell. 2015 Nov;14(11):1135-43,acgelli@ucdavis.edu,,K Vu 2015,2015,2 genes,Vu-2015-The Cch1-Mid1 high-affinity calcium ch,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8563,PHI:6560,UniProt,Q5KM96,GenBank,AAW41864,,,JEC21,mid1,,,,,,PHI:6561,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,high-affinity calcium channel,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene mutation,,,RP,26385891,PubMed,10.1128/EC.00100-15,Eukaryot Cell. 2015 Nov;14(11):1135-43,acgelli@ucdavis.edu,,K Vu 2015,2015,2 genes,Vu-2015-The Cch1-Mid1 high-affinity calcium ch,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8564,PHI:6561,UniProt,Q1HHN2,GenBank,ABF46942,,,H99,Cch1,,,,,,PHI:6560,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,high-affinity calcium channel,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene mutation,,,RP,26385891,PubMed,10.1128/EC.00100-15,Eukaryot Cell. 2015 Nov;14(11):1135-43,acgelli@ucdavis.edu,,K Vu 2015,2015,2 genes,Vu-2015-The Cch1-Mid1 high-affinity calcium ch,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8565,PHI:6562,UniProt,Q19TM6,GenBank,ABE26690,,,FSC200,FTS 1067,,,,,,,263,Francisella tularensis,351581,FSC200,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,protein-disulfide isomerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,25896829,PubMed,10.1093/femspd/ftv030,Pathog Dis. 2015 Aug;73(6):ftv030,petra.spidlova@unob.cz,"Cooperation of both, the FKBP N-like and the DSBA-like, domains is necessary for the correct function of FTS 1067 protein involved in Francisella tularensis virulence and pathogenesis",I Senitkova 2015,2015,1 gene,"Senitkova-2015-Cooperation of both, the FKBP_N",BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8566,PHI:6563,UniProt,Q6U607,GenBank,AAR07714,,,CG43,iucA,,,,,,,573,Klebsiella pneumoniae,,ST86,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,aerobactin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,RP,26056379,PubMed,10.1128/IAI.00430-15,Infect Immun. 2015 Aug;83(8):3325-33,trusso@acsu.buffalo.edu,"In contrast to aerobactin, the inability to produce enterobactin, salmochelin, or yersiniabactin individually or in combination did not decrease the ex vivo growth/survival in human ascites or serum or decrease virulence in the in vivo infection models.",T A Russo 2015,2015,4 genes,"Russo-2015-Aerobactin, but not yersiniabactin",BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8567,PHI:6564,UniProt,Q6U5X7,GenBank,AAR07744,,,CG43,iroB,,,,,,,573,Klebsiella pneumoniae,,ST86,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,salmochelin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26056379,PubMed,10.1128/IAI.00430-15,Infect Immun. 2015 Aug;83(8):3325-33,trusso@acsu.buffalo.edu,"In contrast to aerobactin, the inability to produce enterobactin, salmochelin, or yersiniabactin individually or in combination did not decrease the ex vivo growth/survival in human ascites or serum or decrease virulence in the in vivo infection models.",T A Russo 2015,2015,4 genes,"Russo-2015-Aerobactin, but not yersiniabactin",BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8568,PHI:6565,UniProt,W9BNM8,GenBank,ANN51031,,,TH1,entB,,,,,,,573,Klebsiella pneumoniae,,ST86,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,enterobactin and salmochelin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26056379,PubMed,10.1128/IAI.00430-15,Infect Immun. 2015 Aug;83(8):3325-33,trusso@acsu.buffalo.edu,"In contrast to aerobactin, the inability to produce enterobactin, salmochelin, or yersiniabactin individually or in combination did not decrease the ex vivo growth/survival in human ascites or serum or decrease virulence in the in vivo infection models.",T A Russo 2015,2015,4 genes,"Russo-2015-Aerobactin, but not yersiniabactin",BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8569,PHI:6566,UniProt,W9BHK4,GenBank,CDO15339,,,Kp52.145,irp2,,,,,,,573,Klebsiella pneumoniae,,ST86,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,yersiniabactin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26056379,PubMed,10.1128/IAI.00430-15,Infect Immun. 2015 Aug;83(8):3325-33,trusso@acsu.buffalo.edu,"In contrast to aerobactin, the inability to produce enterobactin, salmochelin, or yersiniabactin individually or in combination did not decrease the ex vivo growth/survival in human ascites or serum or decrease virulence in the in vivo infection models.",T A Russo 2015,2015,4 genes,"Russo-2015-Aerobactin, but not yersiniabactin",BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8570,PHI:6565,UniProt,W9BNM8,GenBank,ANN51031,,,TH1,entB,,,,,,PHI:6566,573,Klebsiella pneumoniae,,ST86,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,enterobactin and salmochelin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26056379,PubMed,10.1128/IAI.00430-15,Infect Immun. 2015 Aug;83(8):3325-33,trusso@acsu.buffalo.edu,"In contrast to aerobactin, the inability to produce enterobactin, salmochelin, or yersiniabactin individually or in combination did not decrease the ex vivo growth/survival in human ascites or serum or decrease virulence in the in vivo infection models.",T A Russo 2015,2015,4 genes,"Russo-2015-Aerobactin, but not yersiniabactin",BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8571,PHI:6566,UniProt,W9BHK4,GenBank,CDO15339,,,Kp52.145,irp2,,,,,,PHI:6565,573,Klebsiella pneumoniae,,ST86,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,yersiniabactin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,RP,26056379,PubMed,10.1128/IAI.00430-15,Infect Immun. 2015 Aug;83(8):3325-33,trusso@acsu.buffalo.edu,"In contrast to aerobactin, the inability to produce enterobactin, salmochelin, or yersiniabactin individually or in combination did not decrease the ex vivo growth/survival in human ascites or serum or decrease virulence in the in vivo infection models.",T A Russo 2015,2015,4 genes,"Russo-2015-Aerobactin, but not yersiniabactin",BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8572,PHI:6567,UniProt,P31058,GenBank,AAC73246,,,MG1655,yadC,,,,,,,562,Escherichia coli,1144302,APEC strain SCI-07,colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,lung; liver; heart,fimbrial-like adhesin protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26502907,PubMed,10.1128/IAI.01138-15,Infect Immun. 2015 Oct 26;84(1):187-93,wds@unicamp.br,Motility assays in soft agar demonstrated that the yadC strain was less motile than the wild type (P < 0.01).,R Verma 2015,2015,1 gene,Verma-2015-Fimbria-encoding gene yadC has a pl,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8573,PHI:6568,UniProt,A0Q494,GenBank,ABK89059,,,U112,REP34,,,,,,,263,Francisella tularensis,376619,LVS,tularemia,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,carboxypeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25231992,PubMed,10.1074/jbc.M114.599381,J Biol Chem. 2014 Oct 31;289(44):30668-79,rasley2@llnl.gov,,G K Feld 2014,2014,1 gene,Feld-2014-Structure and Function of REP34 Impl,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8574,PHI:6568,UniProt,A0Q494,GenBank,ABK89059,,,U112,REP34,,,,,,,263,Francisella tularensis,376619,LVS,tularemia,primates,9606,Homo sapiens (related: human),,,,THP-1 cell,carboxypeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,25231992,PubMed,10.1074/jbc.M114.599381,J Biol Chem. 2014 Oct 31;289(44):30668-79,rasley2@llnl.gov,,G K Feld 2014,2014,1 gene,Feld-2014-Structure and Function of REP34 Impl,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8575,PHI:6569,UniProt,D4ALV9,GenBank,EFE36368,,,CBS 112371,SUB6,,SUB6::hph,,,,,523103,Trichophyton mentagrophytes,,360-A,ringworm,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,skin; spleen; lymph node,subtilisin serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,RP,26333355,PubMed,10.1093/mmy/myv071,Med Mycol. 2016 Jan;54(1):59-71,csamalin@sina.com,"The SUB6::hph -infected animals showed attenuated clinical symptoms and pathological changes, and because of the persistently high level of immunosuppressive cytokine IL-10, the increase in DTH-related cytokines IFN-gamma , TNF-alpha and IL-12 was delayed and lower than that in animals infected with the wild-type strain.",Y shi 2015,2015,1 gene,Shi-2015-Assessment of the function of SUB6 in,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8576,PHI:6570,UniProt,A0A0E2G7L7,GenBank,ENV39340,,,NIPH 386,lpxD,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,UDP-3-O-acylglucosamine N-acyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26311838,PubMed,10.1093/jac/dkv244,J Antimicrob Chemother. 2015 Nov;70(11):2981-6,jvila@ub.edu,,X Vila-Farres 201,2015,1 gene,Vila-Farres-2015-Loss of LPS is involved in th,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8577,PHI:6571,UniProt,O51254,GenBank,AAC66635,,,B31,BB0238,,,,BB0323,UniProt: O51302; GenBank: AAC66700,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; heart,facilitates infection and transmission,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25139020,PubMed,10.1093/infdis/jiu460,J Infect Dis. 2015 Feb 1;211(3):462-71,upal@umd.edu,"Deletion of bb0238 in infectious B. burgdorferi did not affect microbial growth in vitro or survival in ticks, but the mutant was unable to persist in mice or transmit from ticks—defects that are restored on genetic complementation.",T Kariu 2014,2014,1 gene,Kariu-2014-Two Borrelia burgdorferi proteins -,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8578,PHI:6571,UniProt,O51254,GenBank,AAC66635,,,B31,BB0238,,,,BB0323,UniProt: O51302; GenBank: AAC66700,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,facilitates infection and transmission,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,25139020,PubMed,10.1093/infdis/jiu460,J Infect Dis. 2015 Feb 1;211(3):462-71,upal@umd.edu,"Deletion of bb0238 in infectious B. burgdorferi did not affect microbial growth in vitro or survival in ticks, but the mutant was unable to persist in mice or transmit from ticks—defects that are restored on genetic complementation.",T Kariu 2014,2014,1 gene,Kariu-2014-Two Borrelia burgdorferi proteins -,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8579,PHI:6572,UniProt,Q7VNE6,GenBank,AAP95533,,,35000HP,dksA,,,,,,,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,,RNA polymerase-binding transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26056381,PubMed,10.1128/IAI.00692-15,Infect Immun. 2015 Aug;83(8):3281-92,sspinola@iupui.edu,DksA and (p)ppGpp Have Unique and Overlapping Contributions to Haemophilus ducreyi Pathogenesis in Humans.,C L Holley 2015,2015,1 gene,Holley-2015-DksA and (p)ppGpp Have Unique and,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8580,PHI:6573,UniProt,I1RJU1,GenBank,CEF79075,,,PH-1,FgNoxR,chromosome 2,,,FgRac1; FgNoxA,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,A regulatory subunit of NADPH oxidases,,,,reduced virulence,yes,,,,,reduced,reduced,,reduced,no,,,,,,,gene deletion: full,,,RP,26607286,PubMed,10.1093/femsle/fnv223,FEMS Microbiol Lett. 2016 Jan;363(1):fnv223,wenyingyu2004@126.com,"Deletion of the FgNOXR gene results in reduced conidiation and germination. Importantly, sexual development is totally abolished in the FgNOXR deletion mutant. In addition, the disease lesion of FgNOXR deletion mutant is limited to the inoculated spikelets of wheat heads.",C Zhang 2015,2015,1 gene,"Zhang-2015-FgNoxR, a regulatory subunit of NAD",BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8581,PHI:6575,UniProt,Q4UWF4,GenBank,AFP74845,,,8004,avrAC (XopAC),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf vein,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,AC,23951354,PubMed,10.1371/journal.pone.0073469,PLoS One.2013 Aug 9;8(8):e73469,laurent.noel@toulouse.inra.fr,Col-0 is resistant to wildtype Xcc AvrAC (XopAC) and susceptible to mutated Xcc AvrAC (XopAC).,Guy et al 2013,2013,,xopAC-triggered Immunity againstXanthomonasDepends on ArabidopsisReceptor-Like Cytoplasmic Kinase GenesPBL2andRIPK,AC minimal first host target curation,2017-02-20,AC,,,,,,,,,,,,,
,,Record 8582,PHI:6575,UniProt,Q4UWF4,GenBank,AFP74845,,,8004,avrAC (XopAC),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,PBL2 (Serine/threonine-protein kinase),UniProt: O49839,interacts in yeast two-hybrid,,other evidence: yeast two-hybrid,,,AC,23951354,PubMed,10.1371/journal.pone.0073469,PLoS One.2013 Aug 9;8(8):e73469,laurent.noel@toulouse.inra.fr,"Minimal curation. Wild-type Col-0 is resistant to wildtype Xcc AvrAC (XopAC), mutant Col-pbl2 is susceptible to wildtype Xcc AvrAC (XopAC).",Guy et al 2013,2013,,xopAC-triggered Immunity againstXanthomonasDepends on ArabidopsisReceptor-Like Cytoplasmic Kinase GenesPBL2andRIPK,AC minimal first host target curation,2017-02-20,AC,,,,,,,,,,,,,
,,Record 8583,PHI:6575,UniProt,Q4UWF4,GenBank,AFP74845,,,8004,avrAC (XopAC),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,RIPK (Serine/threonine-protein kinase),UniProt: Q9ZUF4,interacts in yeast two-hybrid,,other evidence: yeast two-hybrid,,,AC,23951354,PubMed,10.1371/journal.pone.0073469,PLoS One.2013 Aug 9;8(8):e73469,laurent.noel@toulouse.inra.fr,"Minimal curation. Wild-type Col-0 is resistant to wildtype Xcc AvrAC (XopAC), mutant Col-ripk is susceptible to wildtype Xcc AvrAC (XopAC).",Guy et al 2013,2013,,xopAC-triggered Immunity againstXanthomonasDepends on ArabidopsisReceptor-Like Cytoplasmic Kinase GenesPBL2andRIPK,AC minimal first host target curation,2017-02-20,AC,,,,,,,,,,,,,
,,Record 8584,PHI:6574,UniProt,Q4UWF4,GenBank,AFP74845,,,8004,avrAC (XopAC),,1:1 mix of WT strain XccB186 and XccB186(delta)avrAC deletion strain,,,,,339,Xanthomonas campestris,340,pv. campestris strain B186,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,wildtype BIK1 and PBL2,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,reduced virulence of mutant strain,,gene mutation,,,RP,26355215,PubMed,10.1016/j.chom.2015.08.004,Cell Host Microbe. 2015 Sep 9;18(3):285-95,jmzhou@genetics.ac.cn,"Reduced virulence. In contrast to BIK1, PBL2 uridylylation is specifically required for host recognition of AvrAC to trigger immunity, but not AvrAC virulence.",G Wang 2015,2015,3 genes,Wang-2015-The Decoy Substrate of a Pathogen Ef,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8585,PHI:6574,UniProt,Q4UWF4,GenBank,AFP74845,,,8004,avrAC (XopAC),,1:1 mix of WT strain XccB186 and XccB186(delta)avrAC deletion strain,,,,,339,Xanthomonas campestris,340,pv. campestris strain B186,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,BIK1 (bik1 mutant) (Serine/threonine-protein kinase),UniProt: O48814; GenBank: AAB97121,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,reduced virulence of mutant strain,,gene mutation,,,RP,26355215,PubMed,10.1016/j.chom.2015.08.004,Cell Host Microbe. 2015 Sep 9;18(3):285-95,jmzhou@genetics.ac.cn,"Reduced virulence. In contrast to BIK1, PBL2 uridylylation is specifically required for host recognition of AvrAC to trigger immunity, but not AvrAC virulence.",G Wang 2015,2015,3 genes,Wang-2015-The Decoy Substrate of a Pathogen Ef,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8586,PHI:6574,UniProt,Q4UWF4,GenBank,AFP74845,,,8004,avrAC (XopAC),,1:1 mix of WT strain XccB186 and XccB186(delta)avrAC deletion strain,,,,,339,Xanthomonas campestris,340,pv. campestris strain B186,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,PBL2 (pbl2 mutant) (Serine/threonine-protein kinase),UniProt: O49839,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,unaffected pathogenicity of mutant strain,,gene mutation,,,RP,26355215,PubMed,10.1016/j.chom.2015.08.004,Cell Host Microbe. 2015 Sep 9;18(3):285-95,jmzhou@genetics.ac.cn,"Unaffected pathogenicity. In contrast to BIK1, PBL2 uridylylation is specifically required for host recognition of AvrAC to trigger immunity, but not AvrAC virulence.",G Wang 2015,2015,3 genes,Wang-2015-The Decoy Substrate of a Pathogen Ef,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8587,PHI:6574,UniProt,Q4UWF4,GenBank,AFP74845,,,8004,avrAC (XopAC),,,,,,,339,Xanthomonas campestris,340,pv. campestris strain B186,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,PBL2 (Serine/threonine-protein kinase)(a paralog of BIK1),UniProt: O49839,interaction in co-IP,,other evidence: co-IP,,,AC,26355215,PubMed,10.1016/j.chom.2015.08.004,Cell Host Microbe. 2015 Sep 9;18(3):285-95,jmzhou@genetics.ac.cn,"a CC-NLR (ZAR1), a specific RLCK XII member (RKS1), and a specific RLCK VII member (PBL2) act together to mediate AvrAC-induced ETI against Xcc. ZAR1 and RKS1 form a preactivation complex independently of pathogen challenge. The uridylylation of PBL2 at both Ser253 and Thr254 by AvrAC triggers the PBL2- RKS1 interaction and thus the assembly of an ETI-competent PBL2-RKS1-ZAR1 complex",G Wang 2015,2015,,Wang-2015-The Decoy Substrate of a Pathogen Ef,BATCH_062B/ AC minimal first host target curation,2017-02-21,AC,,,,,,,,,,,,,
,,Record 8588,PHI:6577,UniProt,O33641,GenBank,AAC45084,,,M90T,IcsP,,,,,,,623,Shigella flexneri,1086030,M90T,shigellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,outer membrane protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,26025071,PubMed,10.1093/femsle/fnv088,FEMS Microbiol Lett. 2015 Jun;362(12):fnv088,renato.morona@adelaide.edu.au,Behaviour of the mutants in two mouse models suggests functional expression of icsP might limit bacterial persistence and the associated inflammation in host tissues,E N H Tran 2015,2015,1 gene,Tran-2015-Shigella flexneri cell-to-cell sprea,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8589,PHI:6579,UniProt,A0A0H3JS81,GenBank,BAB43798,,,N315,VraD,,,,,,PHI:6580; PHI:6581,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,involved in gallidermin and daptomycin resistance,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26856834,PubMed,10.1128/AAC.02865-15,Antimicrob Agents Chemother. 2016 Mar 25;60(4):2391-401,friedrich.goetz@uni-tuebingen.de,"In an invertebrate infection model, VraDEH significantly enhanced S. aureus pathogenicity.",P Popella 2016,2016,3 genes,Popella-2016-VraH Is the Third Component of th,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8590,PHI:6580,UniProt,A0A0H3JUP1,GenBank,BAB58864,,,Mu50,VraE,,,,,,PHI:6579; PHI:6581,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,involved in gallidermin and daptomycin resistance,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26856834,PubMed,10.1128/AAC.02865-15,Antimicrob Agents Chemother. 2016 Mar 25;60(4):2391-401,friedrich.goetz@uni-tuebingen.de,"In an invertebrate infection model, VraDEH significantly enhanced S. aureus pathogenicity.",P Popella 2016,2016,3 genes,Popella-2016-VraH Is the Third Component of th,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8591,PHI:6581,UniProt,A0A0H2XE72,GenBank,ABD20541,,,USA300_FPR3757,VraH,,,,,,PHI:6579; PHI:6580,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,involved in gallidermin and daptomycin resistance,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26856834,PubMed,10.1128/AAC.02865-15,Antimicrob Agents Chemother. 2016 Mar 25;60(4):2391-401,friedrich.goetz@uni-tuebingen.de,"In an invertebrate infection model, VraDEH significantly enhanced S. aureus pathogenicity.",P Popella 2016,2016,3 genes,Popella-2016-VraH Is the Third Component of th,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8592,PHI:6582,UniProt,Q6FRR4,GenBank,CAG60013,,,CBS 138,Cgatg32,chromosome H,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen,autophagy-related protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27347716,PubMed,10.1080/15548627.2016.1183080,Autophagy. 2016 Aug 2;12(8):1259-71,ktanabe@agr.ryukoku.ac.jp,"ATG32 is involved in mitophagy in C. Glabrata which occurs in an iron-poor host tissue environment, and it may contribute to the longevity of cells, mitochondrial quality control, and pathogenesis.",M Nagi 2016,2016,1 gene,Nagi-2016-Iron-depletion promotes mitophagy to,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8593,PHI:6582,UniProt,Q6FRR4,GenBank,CAG60013,,,CBS 138,Cgatg32,chromosome H,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney; spleen,autophagy-related protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27347716,PubMed,10.1080/15548627.2016.1183080,Autophagy. 2016 Aug 2;12(8):1259-71,ktanabe@agr.ryukoku.ac.jp,"ATG32 is involved in mitophagy in C. Glabrata which occurs in an iron-poor host tissue environment, and it may contribute to the longevity of cells, mitochondrial quality control, and pathogenesis.",M Nagi 2016,2016,1 gene,Nagi-2016-Iron-depletion promotes mitophagy to,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8594,PHI:6583,UniProt,Q9KQS8,GenBank,AAF95068,,,O1 biovar El Tor str. N16961,LonA,,,,,,,666,Vibrio cholerae,,serotype O1 biovar El Tor strain A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine,"protease regulates biofilm formation, motility, virulence, and the type VI secretion system",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,26755629,PubMed,10.1128/JB.00741-15,J Bacteriol. 2016 Jan 11;198(6):973-85,fyildiz@ucsc.edu,"LonA Protease Regulates Biofilm Formation, Motility, Virulence, and the Type VI Secretion System in Vibrio cholerae.",A Rogers 2016,2016,1 gene,Rogers-2016-The LonA protease regulates biofil,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8595,PHI:6584,UniProt,Q2FV99,GenBank,AFP47630,,,MTCC96,SrtA,,,,,,,1280,Staphylococcus aureus,,Newman D2C,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; liver; kidney,cysteine transpeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,26054573,PubMed,10.1093/femspd/ftv042,Pathog Dis. 2015 Aug;73(6):ftv042,wangdc@jlu.edu.cn,"The results suggested that deletion of SrtA reduced the bacterial burden on the heart, liver and kidneys by blunting the host proinflammatory cytokine response at an early point in infection.",L Wang 2015,2015,1 gene,Wang-2015-A coagulase-negative and nonhemolyti,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8596,PHI:6585,UniProt,J9VJ99,GenBank,AFR93481,,,H99,Pfa4,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,palmitoyltransferase,,,,reduced virulence,yes,,,,,,,aberrant,,no,SDS; caffeine;Congo red; calcofluor white,congo red: CHEBI:34653; SDS: CHEBI:8984; caffeine: CHEBI:27732; calcofluor white: CHEBI:50011,,,,,gene mutation; gene complementation,,,RP,25862155,PubMed,10.1128/EC.00010-15,Eukaryot Cell. 2015 Jul;14(7):626-35,andrew.alspaugh@duke.edu,"Full Ras1 palmitoylation and function required one particular PAT, Pfa4, and deletion of the PFA4 gene in C. neoformans resulted in altered Ras1 localization to membranes, impaired growth at 37°C, and reduced virulence.",C B Nichols 2015,2015,1 gene,Nichols-2015-Impact of protein palmitoylation,BATCH_062B,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8597,PHI:6586,UniProt,P07637,GenBank,AAA27028,,,,aroA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,3-phosphoshikimate 1-carboxyvinyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27602025,PubMed,10.3389/fmicb.2016.01305,Front Microbiol. 2016 Aug 23;7:1305,fpchavez@uchile.cl,,S Riquelme 2016,2016,7 genes,Riquelme-2016-Relevant Genes Linked to Virulen,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8598,PHI:6587,UniProt,P26471,GenBank,AAA27206,,,LT2,waaL,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,O-antigen ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27602025,PubMed,10.3389/fmicb.2016.01305,Front Microbiol. 2016 Aug 23;7:1305,fpchavez@uchile.cl,,S Riquelme 2016,2016,7 genes,Riquelme-2016-Relevant Genes Linked to Virulen,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8599,PHI:6588,UniProt,P0A1I3,GenBank,AAA16867,,,,invA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,invasion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27602025,PubMed,10.3389/fmicb.2016.01305,Front Microbiol. 2016 Aug 23;7:1305,fpchavez@uchile.cl,,S Riquelme 2016,2016,7 genes,Riquelme-2016-Relevant Genes Linked to Virulen,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8600,PHI:6589,UniProt,A0A0C5PM61,GenBank,AJQ18301,,,KC14TY44,ssaD,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,type III secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27602025,PubMed,10.3389/fmicb.2016.01305,Front Microbiol. 2016 Aug 23;7:1305,fpchavez@uchile.cl,,S Riquelme 2016,2016,7 genes,Riquelme-2016-Relevant Genes Linked to Virulen,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8601,PHI:6590,UniProt,H9L4K2,GenBank,CAC48204,,,SR-11,clpV,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27602025,PubMed,10.3389/fmicb.2016.01305,Front Microbiol. 2016 Aug 23;7:1305,fpchavez@uchile.cl,,S Riquelme 2016,2016,7 genes,Riquelme-2016-Relevant Genes Linked to Virulen,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8602,PHI:6591,UniProt,P0DM78,GenBank,AAA27188,,,,phoP,,,,,,PHI:6592,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,virulence transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27602025,PubMed,10.3389/fmicb.2016.01305,Front Microbiol. 2016 Aug 23;7:1305,fpchavez@uchile.cl,,S Riquelme 2016,2016,7 genes,Riquelme-2016-Relevant Genes Linked to Virulen,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8603,PHI:6592,UniProt,P0DM80,GenBank,AAA27189,,,,phoQ,,,,,,PHI:6591,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,cellular slime molds,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,virulence sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27602025,PubMed,10.3389/fmicb.2016.01305,Front Microbiol. 2016 Aug 23;7:1305,fpchavez@uchile.cl,,S Riquelme 2016,2016,7 genes,Riquelme-2016-Relevant Genes Linked to Virulen,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8604,PHI:6593,UniProt,Q87XG7,GenBank,NP_793972,,,DC3000,Cip1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,Pip1; Rcr3,UniProt: Q156I2; GenBank: ABG23376; UniProt: Q8S333; GenBank: AAM19209,,,gene mutation; gene complementation,,,RP,27603016,PubMed,10.1371/journal.ppat.1005874,PLoS Pathog. 2016 Sep 7;12(9):e1005874,renier.vanderhoorn@plants.ox.ac.uk,"Cip1 also inhibits immune protease Pip1, which is known to suppress PtoDC3000 infection, but has a lower affinity for its close homolog Rcr3, explaining why this protein is not recognized in tomato plants carrying the Cf-2 resistance gene, which uses Rcr3 as a co-receptor to detect pathogen-derived protease inhibitors.",T Shindo 2016,2016,1 gene,Shindo-2016-Screen of Non-annotated Small Secr,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8605,PHI:6594,UniProt,Q87WP3,GenBank,AAO57950,,,DC3000,carA,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,encodes the predicted small chain of carbamoylphosphate synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,27558694,PubMed,10.1186/s12866-016-0819-z,BMC Microbiol. 2016 Aug 24;16(1):194,Melanie.filiatrault@ars.usda.gov,deltacarA showed reduced fitness in tomato as well as Arabidopsis when compared to the wild-type strain.,B G Butcher 2016,2016,1 gene,Butcher-2016-Disruption of the carA gene in Ps,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8606,PHI:6594,UniProt,Q87WP3,GenBank,AAO57950,,,DC3000,carA,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,encodes the predicted small chain of carbamoylphosphate synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,RP,27558694,PubMed,10.1186/s12866-016-0819-z,BMC Microbiol. 2016 Aug 24;16(1):194,Melanie.filiatrault@ars.usda.gov,deltacarA showed reduced fitness in tomato as well as Arabidopsis when compared to the wild-type strain.,B G Butcher 2016,2016,1 gene,Butcher-2016-Disruption of the carA gene in Ps,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8607,PHI:6595,UniProt,A0A0F5B4S7,GenBank,KKA50009,,,RKS2993,SeoC,,,,,,,28901,Salmonella enterica,1078775,subsp. salamae strain 3588/07,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,type III secretion system effector,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,RP,27736780,PubMed,10.1128/IAI.00704-16,Infect Immun. 2016 Nov 18;84(12):3618-3628,g.frankel@imperial.ac.uk,"S. enterica subsp. salamae infection of J774.A1 macrophages inhibited phagocytosis of beads, in a seoC-dependent manner.",D J Pollard 2016,2016,1 gene,Pollard-2016-The type III secretion system eff,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8608,PHI:6596,,no data found,GenBank,WP_019829962,,,,OhrA,,,,AphB; OhrR,UniProt: Q9XC54; GenBank: AAD45271; UniProt: K5UV73; GenBank: EKM29133,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,,,,,reduced virulence,,,,,,,,,,no,H2O2; butyl hydroperoxide; menadione; cumene hydroperoxide; N-acetyl cysteine,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; menadione: CHEBI:28869; cumene hydroperoxide: CHEBI:78673; N-acetyl-L-cysteine: CHEBI:28939,,,,,gene mutation,,,RP,27625149,PubMed,10.1111/mmi.13524,Mol Microbiol. 2016 Dec;102(5):939-949,junzhu@mail.med.upenn.edu,"Reduced forms of both AphB and OhrR directly bind to the ohrA promoter and repress its expression, whereas organic hydroperoxides such as cumene hydroperoxide (CHP) deactivate AphB and OhrR. OhrA is critical for V. cholerae adult mouse colonization but is dispensable when the mice are treated with antioxidants.",Z Liu 2016,2016,2 genes,Liu-2016-Thiol-based switch mechanism of virul,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8609,PHI:6597,UniProt,Q9XC54,GenBank,AAD45271,,,,AphB,,,,OhrR; OhrA,UniProt: K5UV73; GenBank: EKM29133; GenBank: WP_019829962,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,,,,,reduced virulence,,,,,,,,,,no,H2O2; butyl hydroperoxide; menadione; cumene hydroperoxide; N-acetyl cysteine,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; menadione: CHEBI:28869; cumene hydroperoxide: CHEBI:78673; N-acetyl-L-cysteine: CHEBI:28939,,,,,gene mutation,,,RP,27625149,PubMed,10.1111/mmi.13524,Mol Microbiol. 2016 Dec;102(5):939-949,junzhu@mail.med.upenn.edu,"Reduced forms of both AphB and OhrR directly bind to the ohrA promoter and repress its expression, whereas organic hydroperoxides such as cumene hydroperoxide (CHP) deactivate AphB and OhrR. OhrA is critical for V. cholerae adult mouse colonization but is dispensable when the mice are treated with antioxidants.",Z Liu 2016,2016,2 genes,Liu-2016-Thiol-based switch mechanism of virul,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8610,PHI:6598,UniProt,P76498,GenBank,KU295573,,,K12,YfcO,,,,,,,562,Escherichia coli,,DE205B,neonatal meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,heart; brain; liver; lung,,,,,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,RP,27616446,PubMed,10.1016/j.micpath.2016.09.007,Microb Pathog. 2016 Nov;100:56-61,tangfang@njau.edu.cn,"The mutant bacterial loads in the heart, brain and liver were significantly lower (P < 0.05) than those of the WT strain.",Y Li 2016,2016,1 gene,Li-2016-The YfcO fimbriae gene enhances adhere,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8611,PHI:6599,UniProt,Q8Y4H2,GenBank,CAD00548,,,EGD-e,InlP,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,placenta; liver; spleen,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27736782,PubMed,10.1128/IAI.00625-16,Infect Immun. 2016 Nov 18;84(12):3584-3596. Print 2016 Dec.,anna.bakardjiev@ucsf.edu,"In guinea pigs and mice InlP increased placental bacterial burden by a factor of 3-log10, while having only a minor role in other maternal organs. Further, deltainlP was attenuated in intracellular growth in primary human placental organ cultures and trophoblasts.",C Faralla 2016,2016,1 gene,Faralla-2016-InlP - a New Virulence Factor wit,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8612,PHI:6599,UniProt,Q8Y4H2,GenBank,CAD00548,,,EGD-e,InlP,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10141,Cavia porcellus (related: domestic guinea pig),Hartley,,,placenta; liver; spleen,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27736782,PubMed,10.1128/IAI.00625-16,Infect Immun. 2016 Nov 18;84(12):3584-3596. Print 2016 Dec.,anna.bakardjiev@ucsf.edu,"In guinea pigs and mice InlP increased placental bacterial burden by a factor of 3-log10, while having only a minor role in other maternal organs. Further, deltainlP was attenuated in intracellular growth in primary human placental organ cultures and trophoblasts.",C Faralla 2016,2016,1 gene,Faralla-2016-InlP - a New Virulence Factor wit,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8613,PHI:6600,UniProt,Q8RMF4,,,,,,gacS,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,bacteremia,bony fishes,7955,Danio rerio (related: zebrafish),Tübingen,,,,sensor histidine kinase/ global virulence regulator,,,phenylacetic acid catabolism pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27506797,PubMed,10.1073/pnas.1523116113,Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9599-604,anton.peleg@monash.edu,"These data identify a previously unknown mechanism of bacterial-guided neutrophil chemotaxis in vivo, providing insight into the role of bacterial metabolism in host innate immune evasion.",M S Bhuiyan 2016,2016,3 genes,Bhuiyan-2016-Acinetobacter baumannii phenylace,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8614,PHI:6601,UniProt,V5VHJ7,,,,,,gacA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,bacteremia,bony fishes,7955,Danio rerio (related: zebrafish),Tübingen,,,,response regulator,,,phenylacetic acid catabolism pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27506797,PubMed,10.1073/pnas.1523116113,Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9599-604,anton.peleg@monash.edu,"These data identify a previously unknown mechanism of bacterial-guided neutrophil chemotaxis in vivo, providing insight into the role of bacterial metabolism in host innate immune evasion.",M S Bhuiyan 2016,2016,3 genes,Bhuiyan-2016-Acinetobacter baumannii phenylace,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8615,PHI:6602,,no data found,,,,,,paa operon,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,bacteremia,bony fishes,7955,Danio rerio (related: zebrafish),Tübingen,,,,chemoattraction,,,phenylacetic acid catabolism pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27506797,PubMed,10.1073/pnas.1523116113,Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9599-604,anton.peleg@monash.edu,"These data identify a previously unknown mechanism of bacterial-guided neutrophil chemotaxis in vivo, providing insight into the role of bacterial metabolism in host innate immune evasion.",M S Bhuiyan 2016,2016,3 genes,Bhuiyan-2016-Acinetobacter baumannii phenylace,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8616,PHI:6603,UniProt,I1RMW3,,,,,Fg PH-1,FaCdc3 (FGSG_05315.3),,,,,,,282267,Fusarium asiaticum,,zj-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai,,,spike,septin,,,,reduced virulence,yes,,,,,reduced; aberrant,,reduced; aberrant,,no,NaCl; KCl; SDS; Congo red,Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,RP,27666337,PubMed,10.1111/mpp.12492,Mol Plant Pathol. 2016 Sep 26,changjun-chen@njau.edu.cn,Reduced virulence on wheat spikelets was indirectly correlated with a reduced level of deoxynivalenol accumulation.,Y Zhang 2016,2016,2 genes,Zhang-2016-The septins FaCdc3 and FaCdc12 are,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8617,PHI:6604,UniProt,I1RT81,,,,,Fg PH-1,FaCdc12(FGSG_07380),,,,,,,282267,Fusarium asiaticum,,zj-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai,,,spike,septin,,,,reduced virulence,yes,,,,,reduced; aberrant,,reduced; aberrant,,no,NaCl; KCl; SDS; Congo red,Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,RP,27666337,PubMed,10.1111/mpp.12492,Mol Plant Pathol. 2016 Sep 26,changjun-chen@njau.edu.cn,Reduced virulence on wheat spikelets was indirectly correlated with a reduced level of deoxynivalenol accumulation.,Y Zhang 2016,2016,2 genes,Zhang-2016-The septins FaCdc3 and FaCdc12 are,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8618,PHI:6605,UniProt,J9VKY2,GenBank,AFR94101,,,H99,HVA1,chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; brain; lung,hypervirulence-associated,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; NaNO2; NaCl; KCl; sorbitol,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; NaNo2: CHEBI:78870; D-sorbitol: CHEBI:17924,,,,,gene disruption; gene complementation,,,RP,27583447,PubMed,10.1371/journal.ppat.1005849,PLoS Pathog. 2016 Sep 1;12(9):e1005849,erin.mcclelland@mtsu.edu,"Mice infected intravenously with the hva1delta strain had higher fungal burden in the spleen and brain, but lower fungal burden in the lungs, and died faster than mice infected with H99W or the hva1delta+HVA1 strain.",E E McClelland 2016,2016,1 gene,McClelland-2016-A Small Protein Associated wit,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8619,PHI:6606,UniProt,K7QX32,GenBank,AFV74748,,,Pd01,PdSte12,,,,,,,36651,Penicillium digitatum,1170230,Pd1,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,fruit,transcription factor,,,,reduced virulence,,,,,,reduced; aberrant,,,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27479695,PubMed,10.1016/j.ijfoodmicro.2016.07.027,Int J Food Microbiol. 2016 Oct 17;235:93-102,pasantor@upv.es,,L Vilanova 2016,2016,1 gene,Vilanova-2016-Relevance of the transcription f,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8620,PHI:6607,UniProt,G4N9W2,GenBank,EHA50414,,,70-15,ARRDC1,chromosome 4,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,autophagy-associated alphaarrestin,,,,reduced virulence,,no,yes,,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27498554,PubMed,10.1038/srep30963,Sci Rep. 2016 Aug 8;6:30963,DBZJU@outlook.com,"Although germ tubes normally develop appressoria, penetration peg formation is dramatically impaired and deltaarrdc1 mutants are mostly nonpathogenic.",B Dong 2016,2016,1 gene,Dong-2016-Autophagy-associated alpha-arrestin,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8621,PHI:6608,UniProt,S7UQS3,GenBank,EPR59982,,,GT1,gra39,,,,,,,5811,Toxoplasma gondii,,Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,dense granule protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27486190,PubMed,10.1128/mBio.00808-16,MBio. 2016 Aug 2;7(4). pii: e00808-16,pbradley@ucla.edu,"Disruption of GRA39 results in slow-growing parasites that contain striking lipid deposits in the parasitophorous vacuole, suggesting a role in lipid regulation that is important for parasite growth.",S M Nadipuram 2016,2016,1 gene,Nadipuram-2016-In Vivo Biotinylation of the To,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8622,PHI:6609,UniProt,Q5ZUD9,GenBank,AAU27938,,,Philadelphia 1,ClpP,,,,,,,446,Legionella pneumophila,,Lp02pj,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,involved in various cellular processes as well as virulence in bacteria,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27484084,PubMed,10.1186/s12866-016-0790-8,BMC Microbiol. 2016 Aug 2;16(1):174.,luyj@mail.sysu.edu.cn,The clpP-deficient L. pneumophila strain failed to replicate and was digested in the first 3 h post-infection in mammalian cells J774A.1.,B Zhao 2016,2016,1 gene,Zhao-2016-ClpP-deletion impairs the virulence,BATCH_063A,2016-11-01,MC,,,,,,,,,,,,,
,,Record 8623,PHI:6610,UniProt,T1Y5Y5,GenBank,AGU60295,,,CN1,ausA,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,encodes subunits of the non-ribosomal peptide synthase,,,,reduced virulence,,,,,,,,,,no,synthetic aureusimine B (phevalin),synthetic aureusimine B (phevalin) CAS: CAS:170713-71-0,,,,,gene mutation; gene complementation,,,RP,27632173,PubMed,10.1371/journal.ppat.1005857,PLoS Pathog. 2016 Sep 15;12(9):e1005857,martin.fraunholz@uni-wuerzburg.de,Non-ribosomal peptide synthetase (NRPS) is required for efficient phagosomal escape and intracellular survival of S. aureus as well as induction of host cell death.,S Blättner 2016,2016,2 genes,Blattner-2016-Staphylococcus aureus Exploits a,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8624,PHI:6611,UniProt,T1Y4W2,GenBank,AGU60296,,,CN1,ausB,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,phosphopantetheinyl transferase,,,,reduced virulence,,,,,,,,,,no,synthetic aureusimine B (phevalin),synthetic aureusimine B (phevalin) CAS: CAS:170713-71-0,,,,,gene mutation; gene complementation,,,RP,27632173,PubMed,10.1371/journal.ppat.1005857,PLoS Pathog. 2016 Sep 15;12(9):e1005857,martin.fraunholz@uni-wuerzburg.de,Non-ribosomal peptide synthetase (NRPS) is required for efficient phagosomal escape and intracellular survival of S. aureus as well as induction of host cell death.,S Blättner 2016,2016,2 genes,Blattner-2016-Staphylococcus aureus Exploits a,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8625,PHI:6612,UniProt,G4NCI6,GenBank,EHA48283,,,70-15,Mocapn9,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,calpain,,,,unaffected pathogenicity,no,,,,,wild type,wild type,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8626,PHI:6613,UniProt,G4N265,GenBank,EHA51681,,,70-15,Mocapn14,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,calpain,,,,unaffected pathogenicity,no,,,,,wild type,wild type,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8627,PHI:6614,UniProt,G4N7X4,GenBank,EHA50928,,,70-15,Mocapn7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,calpain,,,,reduced virulence,yes,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8628,PHI:6615,UniProt,G4MU60,GenBank,EHA53941,,,70-15,Mocapn4,,,,,,PHI:6614,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,calpain,,,,reduced virulence,yes,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8629,PHI:6614,UniProt,G4N7X4,GenBank,EHA50928,,,70-15,Mocapn7,,,,,,PHI:6615,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,calpain,,,,reduced virulence,yes,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8630,PHI:6612,UniProt,G4NCI6,GenBank,EHA48283,,,70-15,Mocapn9,,,,,,PHI:6614,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,calpain,,,,reduced virulence,yes,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8631,PHI:6614,UniProt,G4N7X4,GenBank,EHA50928,,,70-15,Mocapn7,,,,,,PHI:6612,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,calpain,,,,reduced virulence,yes,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8632,PHI:6612,UniProt,G4NCI6,GenBank,EHA48283,,,70-15,Mocapn9,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,calpain,,,,unaffected pathogenicity,no,,,,,wild type,wild type,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8633,PHI:6613,UniProt,G4N265,GenBank,EHA51681,,,70-15,Mocapn14,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,calpain,,,,unaffected pathogenicity,no,,,,,wild type,wild type,wild type,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8634,PHI:6614,UniProt,G4N7X4,GenBank,EHA50928,,,70-15,Mocapn7,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,calpain,,,,reduced virulence,yes,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8635,PHI:6615,UniProt,G4MU60,GenBank,EHA53941,,,70-15,Mocapn4,,,,,,PHI:6614,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,calpain,,,,reduced virulence,yes,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8636,PHI:6614,UniProt,G4N7X4,GenBank,EHA50928,,,70-15,Mocapn7,,,,,,PHI:6615,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,calpain,,,,reduced virulence,yes,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8637,PHI:6612,UniProt,G4NCI6,GenBank,EHA48283,,,70-15,Mocapn9,,,,,,PHI:6614,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,calpain,,,,reduced virulence,yes,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8638,PHI:6614,UniProt,G4N7X4,GenBank,EHA50928,,,70-15,Mocapn7,,,,,,PHI:6612,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,calpain,,,,reduced virulence,yes,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,RP,27502542,PubMed,10.1038/srep31204,Sci Rep. 2016 Aug 9;6:31204,fuchenglin@zju.edu.cn,"The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the deltaMocapn7, deltaMocapn4deltaMocapn7 and deltaMocapn9deltaMocapn7 mutants showed reduced pathogenicity on rice and barley.",X Liu 2016,2016,4 genes,Liu-2016-Calpains are involved in asexual and,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8639,PHI:6616,UniProt,W9BB63,GenBank,AIT00739,,,PMK1,CRP,,,,allS,UniProt: Q765S2; GenBank: BAD14988,,573,Klebsiella pneumoniae,484021,K2044,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,cAMP receptor protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27502416,PubMed,10.1016/j.gene.2016.08.006,Gene. 2016 Nov 15;593(1):28-33,jfqiu@126.com,"CRP is an essential virulence regulator and knock out of crp gene will result in reduced virulence in K. pneumoniae. In the meantime, the transcription of gene allS is positively regulated by CRP via directly binding to upstream of allS promoter.",J Xue 2016,2016,1 gene,Xue-2016-Influence of cAMP receptor protein (C,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8640,PHI:6617,UniProt,I6X8R2,GenBank,AIR12922,,,H37Rv,Zmp1,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,zinc metalloprotease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,RP,27621726,PubMed,10.3389/fmicb.2016.01347,Front Microbiol. 2016 Aug 29;7:1347,sbsl@uohyd.ac.in,d-Tomato labeled M. marinum (TdM. marinum) when injected with rZmp1 showed increased dissemination to tail region from the site of injection as compared to the untreated control fish in a dose-dependent manner.,M H Vemula 2016,2016,1 gene,Vemula-2016-Mycobacterium tuberculosis Zinc Me,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8641,PHI:6618,UniProt,P13128,GenBank,CAA33223,,,EGD serotype 1/2 a,LLO,,,,,,,1639,Listeria monocytogenes,1334565,EGD,listeriosis,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,listeriolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27669511,PubMed,10.1371/journal.pone.0163747,PLoS One. 2016 Sep 26;11(9):e0163747,watarai@yamaguchi-u.ac.jp,Vitamin A has protective effects against bacterial infection in silkworms,Y Castillo 2016,2016,1 gene,Castillo-2016-Effect of Vitamin A on Listeria,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8642,PHI:6619,UniProt,G2WVY4,GenBank,EGY19754,,,VdLs.17,VdMcm1,,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,269719,Cotinus coggygria (related: smokebush),,,,root,MADS-box transcription factor,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,sorbitol; NaCl; KCl,D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,RP,27536281,PubMed,10.3389/fmicb.2016.01192,Front Microbiol. 2016 Aug 3;7:1192,ylwang@bjfu.edu.cn,"MADS-box transcription factor VdMcm1 is a key regulator of conidiation, microsclerotia formation, virulence, and secondary metabolism of V. dahliae. In addition VdMcm1 is involved in cell wall integrity.",D Xiong 2016,2016,1 gene,Xiong-2016-MADS-Box Transcription Factor VdMcm,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8643,PHI:6620,UniProt,Q87CV2,GenBank,AAO28818,,,Temecula1,PrtA,,PrtA-S280A,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Thompson Seedless,,,leaf,antivirulence secreted serine protease,,,,increased virulence (hypervirulence),,,,,,,,aberrant; increased,,no,,,,,,,gene mutation,,,YVS,27492542,PubMed,10.1038/srep31098,Sci Rep. 2016 Aug 5;6:31098.,amdandekar@ucdavis.edu,Hypervirulent response in grapevines is observed when X. fastidiosais is disrupted for production of PrtA and PD (Pierce's disease)-model tobacco plants transformed to express PrtA exhibited decreased symptoms after infection by X. fastidiosa.,H Gouran 2016,2016,1 gene,Gouran-2016-The Secreted Protease PrtA Control,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8644,PHI:6620,UniProt,Q87CV2,GenBank,AAO28818,,,Temecula1,PrtA,,PrtA-S280A,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana SR1,,,leaf,antivirulence secreted serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,27492542,PubMed,10.1038/srep31098,Sci Rep. 2016 Aug 5;6:31098.,amdandekar@ucdavis.edu,Hypervirulent response in grapevines is observed when X. fastidiosais is disrupted for production of PrtA and PD (Pierce's disease)-model tobacco plants transformed to express PrtA exhibited decreased symptoms after infection by X. fastidiosa.,H Gouran 2016,2016,1 gene,Gouran-2016-The Secreted Protease PrtA Control,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8645,PHI:6622,UniProt,H1VA10,GenBank,CCF37063,,,IMI 349063,ChMK1,,,,,,,80884,Colletotrichum higginsianum,,IMI349061,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,mitogen-activated protein kinase,,,,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,,no,SDS; calcofluor; Congo red,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene disruption; gene complementation,,,YVS,27536296,PubMed,10.3389/fmicb.2016.01212,Front Microbiol. 2016 Aug 3;7:1212,82862108@qq.com,"Targeted deletion of ChMK1 resulted in a hypersensitivity to cell wall inhibitors, reduced conidiation and albinistic colonies and the deletion mutant was also unable to form melanized appressorium.",W Wei 2016,2016,1 gene,Wei-2016-Colletotrichum higginsianum Mitogen-A,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8646,PHI:6623,UniProt,A0Q7H5,GenBank,ABK90190,,,U112,IglG,,,,IglF,UniProt: A0Q7H4; GenBank: ABK90189,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen,belongs to a family of PAAR-like T6SS proteins which harbors a unique N-terminal extension required for virulence,,,,loss of pathogenicity,,,,,,,,reduced,,no,KCl,KCl: CHEBI:32588,,,,,gene mutation; gene complementation,,,YVS,27602570,PubMed,10.1371/journal.ppat.1005821,PLoS Pathog. 2016 Sep 7;12(9):e1005821,laurent.terradot@ibcp.fr; anders.Sjostedt@umu.se; thomas.henry@inserm.fr,"Francisella-specific N-terminal alpha-helical extension is not required for IglG secretion, but is critical for F. novicida virulence and for the interaction of IglG with another FPI-encoded protein, IglF.",M Rigard 2016,2016,2 genes,Rigard-2016-Francisella tularensis IglG Belong,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8647,PHI:6624,UniProt,Q5NED3,GenBank,YP_170609,,,SCHU S4,IglG,,,,IglF,UniProt: Q5NED4; GenBank: YP_170608,,263,Francisella tularensis,177416,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,belongs to a family of PAAR-like T6SS proteins which harbors a unique N-terminal extension required for virulence,,,,loss of pathogenicity,,,,,,,,reduced,,no,KCl,KCl: CHEBI:32588,,,,,gene mutation; gene complementation,,,YVS,27602570,PubMed,10.1371/journal.ppat.1005821,PLoS Pathog. 2016 Sep 7;12(9):e1005821,laurent.terradot@ibcp.fr; anders.Sjostedt@umu.se; thomas.henry@inserm.fr,"Francisella-specific N-terminal alpha-helical extension is not required for IglG secretion, but is critical for F. novicida virulence and for the interaction of IglG with another FPI-encoded protein, IglF.",M Rigard 2016,2016,2 genes,Rigard-2016-Francisella tularensis IglG Belong,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8648,PHI:6625,UniProt,Q6FTB1,GenBank,CAG59460,,,CBS 138,CgTpo1_1,chromosome G,,,,,,5478,Candida glabrata,,KUE100,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,drug:H+ antiporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27780306,PubMed,10.1111/cmi.12686,Cell Microbiol. 2016 Oct 25,mnpct@tecnico.ulisboa.pt,"CgTPO1_2 expression was found to be up-regulated during biofilm formation, while its deletion leads to a decreased expression of adhesin-encoding genes during biofilm formation, decreased plasma membrane potential and affect ergosterol and fatty acid content.",R Santos 2016,2016,2 genes,Santos-2016-The multidrug resistance transport,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8649,PHI:6626,UniProt,Q6FV98,GenBank,CAG58765,,,CBS 138,CgTpo1_2,chromosome E,,,,,,5478,Candida glabrata,,KUE100,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,drug:H+ antiporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,27780306,PubMed,10.1111/cmi.12686,Cell Microbiol. 2016 Oct 25,mnpct@tecnico.ulisboa.pt,"CgTPO1_2 expression was found to be up-regulated during biofilm formation, while its deletion leads to a decreased expression of adhesin-encoding genes during biofilm formation, decreased plasma membrane potential and affect ergosterol and fatty acid content.",R Santos 2016,2016,2 genes,Santos-2016-The multidrug resistance transport,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8650,PHI:6627,UniProt,M7THD3,GenBank,EMR80564,,,BcDW1,BcCPA1,,,,BcCPB1,UniProt: M7TEP3; GenBank: EMR81956,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,F-actin capping protein,,,,reduced virulence,,yes,yes,yes,,,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,RP,27647239,PubMed,10.1016/j.funbio.2016.07.007,Fungal Biol. 2016 Oct;120(10):1225-35,Julia.schumacher@uni-muenster.de,"Deletion of bccpa1 had a profound effect on hyphal growth, morphogenesis, and virulence indicating the importance of F-actin capping for an intact actin cytoskeleton. As polarized growth e unlike septum formation e is impaired in the mutants, it can be concluded that the organization and/or localization of actin patches and cables are disturbed rather than the functionality of the actin rings.",V E GONZALEZ-RODRIGUEZ 2016,2016,1 gene,Gonzalez-Rodrig-2016-The F-actin capping prote,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8651,PHI:6628,UniProt,A0A0H2XHD4,GenBank,ABD22043,,,USA300_FPR3757,bcaP,,USA300 bcaP::UNR; EmR (SAUSA300_2538),,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; heart; liver,BCAA transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27589208,PubMed,10.1111/mmi.13495,Mol Microbiol. 2016 Dec;102(5):850-864,deh@uwo.ca,"Despite a predominant role for BrnQ1 in vitro, both BrnQ1 and BcaP are required for S. aureus fitness in vivo in a hematogenous spread infection model and a nasal colonisation model.",J C Kaiser 2016,2016,2 genes,Kaiser-2016-The role of two branched-chain ami,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8652,PHI:6629,UniProt,A0A0H2WXT5,GenBank,AAW37467,,,COL,brnQ1,,USA300 DbrnQ1,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; heart; liver,BCAA transporter,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27589208,PubMed,10.1111/mmi.13495,Mol Microbiol. 2016 Dec;102(5):850-864,deh@uwo.ca,"Despite a predominant role for BrnQ1 in vitro, both BrnQ1 and BcaP are required for S. aureus fitness in vivo in a hematogenous spread infection model and a nasal colonisation model.",J C Kaiser 2016,2016,2 genes,Kaiser-2016-The role of two branched-chain ami,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8653,PHI:6628,UniProt,A0A0H2XHD4,GenBank,ABD22043,,,USA300_FPR3757,bcaP,,USA300 DbrnQ1 bcaP::UNR; EmR,,,,PHI:6629,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; heart; liver,BCAA transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27589208,PubMed,10.1111/mmi.13495,Mol Microbiol. 2016 Dec;102(5):850-864,deh@uwo.ca,"Despite a predominant role for BrnQ1 in vitro, both BrnQ1 and BcaP are required for S. aureus fitness in vivo in a hematogenous spread infection model and a nasal colonisation model.",J C Kaiser 2016,2016,2 genes,Kaiser-2016-The role of two branched-chain ami,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8654,PHI:6629,UniProt,A0A0H2WXT5,GenBank,AAW37467,,,COL,brnQ1,,USA300 DbrnQ1 bcaP::UNR; EmR,,,,PHI:6628,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; heart; liver,BCAA transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27589208,PubMed,10.1111/mmi.13495,Mol Microbiol. 2016 Dec;102(5):850-864,deh@uwo.ca,"Despite a predominant role for BrnQ1 in vitro, both BrnQ1 and BcaP are required for S. aureus fitness in vivo in a hematogenous spread infection model and a nasal colonisation model.",J C Kaiser 2016,2016,2 genes,Kaiser-2016-The role of two branched-chain ami,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8655,PHI:6630,UniProt,Q8PPT1,GenBank,AAM35493,,,306,treA,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,159033,Citrus x aurantiifolia (related: lime),,,,leaf,trehalase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,more drenching and necrosis,gene deletion: full,,,RP,27611974,PubMed,10.1371/journal.pone.0162886,PLoS One. 2016 Sep 9;11(9):e0162886,avalex@uol.com.br,Leaves of Citrus aurantifolia infected with XccdeltatreA showed much more drenching and necrosis than those infected by wild type Xcc.,A V Alexandrino 2016,2016,1 gene,Alexandrino-2016-treA Codifies for a Trehalase,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8656,PHI:6631,,no data found,,,,,,MaUV-40.1,,,,,,,5530,Metarhizium anisopliae,,SM04,fungal keratitis,moths,51655,Plutella xylostella (related: diamondback moth),,,,larva,virulence related,,,,increased virulence (hypervirulence),,,,,,increased,,increased,wild type,no,,,,,,,gene mutation,,,RP,27521024,PubMed,10.1007/s00253-016-7746-7,Appl Microbiol Biotechnol. 2016 Nov;100(21):9217-9228,hzscau@126.com,"Total conidial production, UV and thermal tolerances of the MaUV-40.1 strain were increased, but a reduced secretome was seen for the mutant compared to wild type.",J Zhao 2016,2016,1 gene,Zhao-2016-Screening of Metarhizium anisopliae,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8657,PHI:6632,,no data found,,,,,,MaUV-20.1,,,,,,,5530,Metarhizium anisopliae,,SM04,fungal keratitis,moths,51655,Plutella xylostella (related: diamondback moth),,,,larva,virulence related,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27521024,PubMed,10.1007/s00253-016-7746-7,Appl Microbiol Biotechnol. 2016 Nov;100(21):9217-9228,hzscau@126.com,"Total conidial production, UV and thermal tolerances of the MaUV-40.1 strain were increased, but a reduced secretome was seen for the mutant compared to wild type.",J Zhao 2016,2016,1 gene,Zhao-2016-Screening of Metarhizium anisopliae,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8658,PHI:6633,,no data found,,,,,,MaUV-60.1,,,,,,,5530,Metarhizium anisopliae,,SM04,fungal keratitis,moths,51655,Plutella xylostella (related: diamondback moth),,,,larva,virulence related,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27521024,PubMed,10.1007/s00253-016-7746-7,Appl Microbiol Biotechnol. 2016 Nov;100(21):9217-9228,hzscau@126.com,"Total conidial production, UV and thermal tolerances of the MaUV-40.1 strain were increased, but a reduced secretome was seen for the mutant compared to wild type.",J Zhao 2016,2016,1 gene,Zhao-2016-Screening of Metarhizium anisopliae,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8659,PHI:6634,UniProt,G4N7U4,GenBank,EHA50898,,,70-15,MoDnm1,chromosome 4,,,MoFis1; MoMdv1,UniProt: G4N572; UniProt: A4RJV3,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,dynamin,,,,reduced virulence,,yes,yes,yes,small restricted lesions,reduced,,reduced,,no,,,,,,,gene mutation,,,RP,27556292,PubMed,10.1371/journal.ppat.1005823,PLoS Pathog. 2016 Aug 24;12(8):e1005823,zhgzhang@njau.edu.cn,"MoDnm1, MoFis1 and MoMdv1 are in complex to regulate not only peroxisomal and mitochondrial fission, pexophagy and mitophagy progression, but also appressorium function and host penetration.",K Zhong 2016,2016,6 genes,Zhong-2016-MoDnm1 Dynamin Mediating Peroxisoma,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8660,PHI:6635,UniProt,G4N572,GenBank,EHA52129,,,70-15,MoFis1,chromosome 3,,,MoDnm1; MoMdv1,UniProt: G4N7U4; UniProt: A4RJV3,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitochondria fission protein,,,,reduced virulence,,no,,,,reduced,,reduced,,no,,,,,,,gene mutation,,,RP,27556292,PubMed,10.1371/journal.ppat.1005823,PLoS Pathog. 2016 Aug 24;12(8):e1005823,zhgzhang@njau.edu.cn,"MoDnm1, MoFis1 and MoMdv1 are in complex to regulate not only peroxisomal and mitochondrial fission, pexophagy and mitophagy progression, but also appressorium function and host penetration.",K Zhong 2016,2016,6 genes,Zhong-2016-MoDnm1 Dynamin Mediating Peroxisoma,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8661,PHI:6636,UniProt,A4RJV3,GenBank,EHA54899,,,70-15,MoMdv1,chromosome 2,,,MoDnm1; MoFis1,UniProt: G4N572; UniProt: G4N7U4,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitochondrial division protein,,,,reduced virulence,,no,,,,reduced,,reduced,,no,,,,,,,gene mutation,,,RP,27556292,PubMed,10.1371/journal.ppat.1005823,PLoS Pathog. 2016 Aug 24;12(8):e1005823,zhgzhang@njau.edu.cn,"MoDnm1, MoFis1 and MoMdv1 are in complex to regulate not only peroxisomal and mitochondrial fission, pexophagy and mitophagy progression, but also appressorium function and host penetration.",K Zhong 2016,2016,6 genes,Zhong-2016-MoDnm1 Dynamin Mediating Peroxisoma,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8662,PHI:6637,UniProt,G4N1E7,GenBank,EHA52418,,,70-15,Movps1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,vacuolar protein sorting-associated protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,RP,27556292,PubMed,10.1371/journal.ppat.1005823,PLoS Pathog. 2016 Aug 24;12(8):e1005823,zhgzhang@njau.edu.cn,"MoDnm1, MoFis1 and MoMdv1 are in complex to regulate not only peroxisomal and mitochondrial fission, pexophagy and mitophagy progression, but also appressorium function and host penetration.",K Zhong 2016,2016,6 genes,Zhong-2016-MoDnm1 Dynamin Mediating Peroxisoma,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8663,PHI:6638,UniProt,G4MNQ6,GenBank,EHA56272,,,70-15,Modnm2,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,dynamin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene mutation,,,RP,27556292,PubMed,10.1371/journal.ppat.1005823,PLoS Pathog. 2016 Aug 24;12(8):e1005823,zhgzhang@njau.edu.cn,"MoDnm1, MoFis1 and MoMdv1 are in complex to regulate not only peroxisomal and mitochondrial fission, pexophagy and mitophagy progression, but also appressorium function and host penetration.",K Zhong 2016,2016,6 genes,Zhong-2016-MoDnm1 Dynamin Mediating Peroxisoma,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8664,PHI:6639,UniProt,G4NJH9,GenBank,EHA46395,,,70-15,Modnm3,chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,dynamin,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene mutation,,,RP,27556292,PubMed,10.1371/journal.ppat.1005823,PLoS Pathog. 2016 Aug 24;12(8):e1005823,zhgzhang@njau.edu.cn,"MoDnm1, MoFis1 and MoMdv1 are in complex to regulate not only peroxisomal and mitochondrial fission, pexophagy and mitophagy progression, but also appressorium function and host penetration.",K Zhong 2016,2016,6 genes,Zhong-2016-MoDnm1 Dynamin Mediating Peroxisoma,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8665,PHI:6640,UniProt,G2XIE8,GenBank,EGY19596,,,VdLs.17,VdNoxB,,,,VdPls1,UniProt: G2WVY3,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,catalytic subunit of membrane-bound NADPH oxidases for reactive oxygen species (ROS) production,,,ca2+ signaling,loss of pathogenicity,,yes,,,,,,increased; aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,27463643,PubMed,10.1371/journal.ppat.1005793,PLoS Pathog. 2016 Jul 27;12(7):e1005793,guohs@im.ac.cn,"Together with the loss of virulence of Vddeltanoxb and Vddeltapls1, which are unable to initiate colonization in cotton plants, VdNoxB/VdPls1-mediated ROS production activates VdCrz1 signaling through Ca2+ elevation in hyphopodia, infectious structures of V. dahliae, to regulate penetration peg formation during the initial colonization of cotton roots.",Y Zhao 2016,2016,2 genes,Zhao-2016-Hyphopodium-Specific VdNoxB_VdPls1-D,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8666,PHI:6641,UniProt,G2WVY3,GenBank,EGY19753,,,VdLs.17,VdPls1,chromosome 7,,,VdNoxB,UniProt: G2XIE8,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,tetraspanin,,,ca2+ signaling,loss of pathogenicity,,yes,,,,,,increased; aberrant,,no,,,,,,,gene disruption; gene complementation,,,RP,27463643,PubMed,10.1371/journal.ppat.1005793,PLoS Pathog. 2016 Jul 27;12(7):e1005793,guohs@im.ac.cn,"Together with the loss of virulence of Vddeltanoxb and Vddeltapls1, which are unable to initiate colonization in cotton plants, VdNoxB/VdPls1-mediated ROS production activates VdCrz1 signaling through Ca2+ elevation in hyphopodia, infectious structures of V. dahliae, to regulate penetration peg formation during the initial colonization of cotton roots.",Y Zhao 2016,2016,2 genes,Zhao-2016-Hyphopodium-Specific VdNoxB_VdPls1-D,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8667,PHI:6642,UniProt,Q5NH68,GenBank,CAG45235,,,SCHU S4,fmvB,,,,,,,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,lung; liver; spleen,iron acquisition,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27513341,PubMed,10.1371/journal.pone.0160977,PLoS One. 2016 Aug 11;11(8):e0160977,Jason.Huntley@UToledo.edu,"Function of FmvA remains unknown, FmvB appears to play a role in magnesium uptake and F. tularensis virulence.",X Wu 2016,2016,2 genes,Wu-2016-FmvB_ A Francisella tularensis Magnesi,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8668,PHI:6643,UniProt,Q5NI23,GenBank,CAG44900,,,SCHU S4,fmvA,,,,,,,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,lung; liver; spleen,iron acquisition,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,RP,27513341,PubMed,10.1371/journal.pone.0160977,PLoS One. 2016 Aug 11;11(8):e0160977,Jason.Huntley@UToledo.edu,"Function of FmvA remains unknown, FmvB appears to play a role in magnesium uptake and F. tularensis virulence.",X Wu 2016,2016,2 genes,Wu-2016-FmvB_ A Francisella tularensis Magnesi,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8669,PHI:6644,UniProt,J4KNV2,GenBank,EJP66349,,,ARSEF 2860,CIA30,,,,,,,176275,Beauveria bassiana,,JEF-007,white muscardine,bugs,329032,Riptortus pedestris (bean bug),,,,larva,complex I intermediate-associated protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27470140,PubMed,10.1007/s00253-016-7734-y,Appl Microbiol Biotechnol. 2016 Oct;100(20):8889-900,jskim10@jbnu.ac.kr,Bean bug-pathogenic B. Bassiana could potentially be used as a method on biocontrol,S Kim 2016,2016,2 genes,Kim-2016-Characterization of T-DNA insertion m,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8670,PHI:6645,,no data found,GenBank,KU663179,,,,Atg22,,,,,,,176275,Beauveria bassiana,,JEF-007,white muscardine,bugs,329032,Riptortus pedestris (bean bug),,,,larva,autophagy,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27470140,PubMed,10.1007/s00253-016-7734-y,Appl Microbiol Biotechnol. 2016 Oct;100(20):8889-900,jskim10@jbnu.ac.kr,Bean bug-pathogenic B. Bassiana could potentially be used as a method on biocontrol,S Kim 2016,2016,2 genes,Kim-2016-Characterization of T-DNA insertion m,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8671,PHI:6646,UniProt,Q9I3K2,GenBank,AE004579_11,,,PAO1,TplE,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,H2-T6SS-dependent phospholipase effector,,,IRE1a-XBP1,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,RP,27477276,PubMed,10.1016/j.celrep.2016.07.012,Cell Rep. 2016 Aug 9;16(6):1502-9,zdsys@vip.sina.com,,F Jiang 2016,2016,1 gene,Jiang-2016-The Pseudomonas aeruginosa Type VI,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8672,PHI:6647,UniProt,Q4WX78,GenBank,EAL92725,,,Af293,rlmA,chromosome 3,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,MADS-box transcription factor rlmA required for regulation of the cell wall integrity and virulence.,,,cell wall integrity pathway,loss of pathogenicity,,,,,,,,,,no,"caffeine; calcofluor white (CFW); congo red (CR); anidulafungin, (AF); caspofungin (CASP); sodium dodecyl sulfate (SDS); fluconazole (FLUC); ethylenediaminetetraacetic acid (EDTA); DTT (dithiothreitol)","caffeine: CHEBI:27732; calcofluor white: CHEBI:50011; Congo red (CR): CHEBI:34653; SDS: CHEBI:8984; anidulafungin: CHEBI:55346; caspofungin: CHEBI:474180; fluconazole: CHEBI:46081, CAS:86386-73-4; EDTA: CHEBI:64758; dithiothreitol: CHEBI:42170",,,,,gene deletion: full; gene complementation,,,RP,27473315,PubMed,10.1534/g3.116.031112,G3 (Bethesda). 2016 Sep 8;6(9):2983-3002,imalavazi@ufscar.br,"RlmA functions as a transcription factor in the A. fumigatus CWI pathway, acting downstream of PkcA-MpkA signaling and contributing to the virulence of this fungus.",M C Rocha 2016,2016,1 gene,Rocha-2016-Aspergillus fumigatus MADS-Box Tran,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8673,PHI:6648,UniProt,G7ZK63,GenBank,CBX55340,,,Psn23,hrpA,,hrpA in-frame deletion mutant of Psn23,,,,,29438,Pseudomonas savastanoi,360921,pv. nerii strain Psn23,knot (olive),eudicots,63479,Nerium oleander (related: common oleander),Cesena Italy,,,stem,IAA biosynthesis,,,indole-3-acetamide pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27637152,PubMed,10.1016/j.resmic.2016.09.002,Res Microbiol. 2016 Nov - Dec;167(9-10):774-787,stefania.tegli@unifi.it,,M Cerboneschi 2016,2016,3 genes,Cerboneschi-2016-Indole-3-acetic acid in plant,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8674,PHI:6649,UniProt,A0A0Q0B337,GenBank,AOR51356,,,Psn23,iaaM,,iaaM in-frame deletion mutant of Psn23,,,,,29438,Pseudomonas savastanoi,360921,pv. nerii strain Psn23,knot (olive),eudicots,63479,Nerium oleander (related: common oleander),Cesena Italy,,,stem,IAA biosynthesis,,,indole-3-acetamide pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27637152,PubMed,10.1016/j.resmic.2016.09.002,Res Microbiol. 2016 Nov - Dec;167(9-10):774-787,stefania.tegli@unifi.it,,M Cerboneschi 2016,2016,3 genes,Cerboneschi-2016-Indole-3-acetic acid in plant,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8675,PHI:6650,UniProt,A0A0P9Y928,GenBank,AOR51354,,,Psn23,iaaL,,iaaL in-frame deletion mutant of Psn23,,,,,29438,Pseudomonas savastanoi,360921,pv. nerii strain Psn23,knot (olive),eudicots,63479,Nerium oleander (related: common oleander),Cesena Italy,,,stem,IAA biosynthesis,,,indole-3-acetamide pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,RP,27637152,PubMed,10.1016/j.resmic.2016.09.002,Res Microbiol. 2016 Nov - Dec;167(9-10):774-787,stefania.tegli@unifi.it,,M Cerboneschi 2016,2016,3 genes,Cerboneschi-2016-Indole-3-acetic acid in plant,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8676,PHI:6651,UniProt,P45610,GenBank,CAA48498,,,KAY2026,tonB,,KP273; KPPR1 tonB::kan,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; lung,siderophores synthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27624128,PubMed,10.1128/mBio.01397-16,MBio. 2016 Sep 13;7(5). pii: e01397-16,mikebach@med.umich.edu,"Siderophore secretion by K. pneumoniae induces the secretion of interleukin-6 (IL-6), CXCL1, and CXCL2, as well as bacterial dissemination to the spleen, compared to siderophore-negative mutants at an equivalent bacterial number.",V I Holden 2016,2016,3 genes,Holden-2016-Klebsiella pneumoniae Siderophores,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8677,PHI:6652,UniProt,W9BNM8,GenBank,CDO13425,,,Kp52.145,entB,,KP281; VK089 tonB::kan,,,,PHI:6653; PHI:6651,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; lung,isochorismatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27624128,PubMed,10.1128/mBio.01397-16,MBio. 2016 Sep 13;7(5). pii: e01397-16,mikebach@med.umich.edu,"Siderophore secretion by K. pneumoniae induces the secretion of interleukin-6 (IL-6), CXCL1, and CXCL2, as well as bacterial dissemination to the spleen, compared to siderophore-negative mutants at an equivalent bacterial number.",V I Holden 2016,2016,3 genes,Holden-2016-Klebsiella pneumoniae Siderophores,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8678,PHI:6653,UniProt,W9BHK2,GenBank,AIT04278,,,PMK1,ybtS,,KP281; VK089 tonB::kan,,,,PHI:6652; PHI:6651,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; lung,isochorismate synthase/isochorismate-pyruvate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27624128,PubMed,10.1128/mBio.01397-16,MBio. 2016 Sep 13;7(5). pii: e01397-16,mikebach@med.umich.edu,"Siderophore secretion by K. pneumoniae induces the secretion of interleukin-6 (IL-6), CXCL1, and CXCL2, as well as bacterial dissemination to the spleen, compared to siderophore-negative mutants at an equivalent bacterial number.",V I Holden 2016,2016,3 genes,Holden-2016-Klebsiella pneumoniae Siderophores,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8679,PHI:6651,UniProt,P45610,GenBank,CAA48498,,,KAY2026,tonB,,KP273; KPPR1 tonB::kan,,,,PHI:6652; PHI:6653,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; lung,siderophores synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,RP,27624128,PubMed,10.1128/mBio.01397-16,MBio. 2016 Sep 13;7(5). pii: e01397-16,mikebach@med.umich.edu,"Siderophore secretion by K. pneumoniae induces the secretion of interleukin-6 (IL-6), CXCL1, and CXCL2, as well as bacterial dissemination to the spleen, compared to siderophore-negative mutants at an equivalent bacterial number.",V I Holden 2016,2016,3 genes,Holden-2016-Klebsiella pneumoniae Siderophores,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8680,PHI:6654,UniProt,Q93FB0,GenBank,AAK49483,,,CP9,ireA,,,,,,,562,Escherichia coli,,DE205B,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),,,,,iron-regulated outer membrane virulence protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl,NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,YVS,27531140,PubMed,10.1186/s12917-016-0800-y,BMC Vet Res. 2016 Aug 17;12(1):167,tangfang@njau.edu.cn,"The adhesion ability of the ireA deletion mutant to DF-1 cells was significantly decreased. The survival rate of ireA deletion mutant was reduced 21.17 % (P<0.01), 25.42 (P<0.05) and 70.0 % (P<0.01) under alkali, high osmolarity, and low temperature (4 °C) conditions, respectively, compared with the wild-type strain.",Y Li 2016,2016,1 gene,Li-2016-Iron-regulated gene ireA in avian path,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8681,PHI:6655,UniProt,K5UT82,GenBank,EKM28473,,,HENC-02,ChiS,,,,CBP,UniProt: Q9KLD5; GenBank: AAF96709,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),SWR,,,intestine,two-component sensor histidine kinase,,,chitin utilization pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27670078,PubMed,10.1016/j.ijmm.2016.09.003,Int J Med Microbiol. 2016 Sep 19. pii: S1438-4221(16)30045-5,chatterjeens@icmr.org.in,"Isogenic chiS mutant showed repression in mucin utilization. Disruption of chiS gene has marked effects on survival, motility, mucin penetration and utilization, expression of virulence in V. cholerae.",R Chourashi 2016,2016,1 gene,Chourashi-2016-Role of a sensor histidine kina,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8682,PHI:6655,UniProt,K5UT82,GenBank,EKM28473,,,HENC-02,ChiS,,,,CBP,UniProt: Q9KLD5; GenBank: AAF96709,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,intestine,two-component sensor histidine kinase,,,chitin utilization pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27670078,PubMed,10.1016/j.ijmm.2016.09.003,Int J Med Microbiol. 2016 Sep 19. pii: S1438-4221(16)30045-5,chatterjeens@icmr.org.in,"Isogenic chiS mutant showed repression in mucin utilization. Disruption of chiS gene has marked effects on survival, motility, mucin penetration and utilization, expression of virulence in V. cholerae.",R Chourashi 2016,2016,1 gene,Chourashi-2016-Role of a sensor histidine kina,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8683,PHI:6656,UniProt,A6SE61,GenBank,XP_001550416,,,B05.10,BcDIM5,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,histone H3 lysine 9 methyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,27597848,PubMed,10.3389/fmicb.2016.01289,Front Microbiol. 2016 Aug 22;7:1289,,BcDIM5 knockout transformants showed that the hyphal growth rate and production of conidiophores and sclerotia were significantly reduced.,X Zhang 2016,2016,3 genes,Zhang-2016-Histone H3 Lysine 9 Methyltransfera,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8684,PHI:6656,UniProt,A6SE61,GenBank,XP_001550416,,,B05.10,BcDIM5,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,histone H3 lysine 9 methyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,27597848,PubMed,10.3389/fmicb.2016.01289,Front Microbiol. 2016 Aug 22;7:1289,,BcDIM5 knockout transformants showed that the hyphal growth rate and production of conidiophores and sclerotia were significantly reduced.,X Zhang 2016,2016,3 genes,Zhang-2016-Histone H3 Lysine 9 Methyltransfera,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8685,PHI:6656,UniProt,A6SE61,GenBank,XP_001550416,,,B05.10,BcDIM5,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3847,Glycine max (related: soybean),,,,leaf,histone H3 lysine 9 methyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,27597848,PubMed,10.3389/fmicb.2016.01289,Front Microbiol. 2016 Aug 22;7:1289,,BcDIM5 knockout transformants showed that the hyphal growth rate and production of conidiophores and sclerotia were significantly reduced.,X Zhang 2016,2016,3 genes,Zhang-2016-Histone H3 Lysine 9 Methyltransfera,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8686,PHI:6657,UniProt,A6SIZ9,GenBank,XP_001548821,,,B05.10,BcDIM2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,DNAmethyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,27597848,PubMed,10.3389/fmicb.2016.01289,Front Microbiol. 2016 Aug 22;7:1289,,BcDIM5 knockout transformants showed that the hyphal growth rate and production of conidiophores and sclerotia were significantly reduced.,X Zhang 2016,2016,3 genes,Zhang-2016-Histone H3 Lysine 9 Methyltransfera,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8687,PHI:6658,UniProt,A6S1X3,GenBank,XP_001554784,,,B05.10,BcHP1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,heterochromatinprotein1,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,27597848,PubMed,10.3389/fmicb.2016.01289,Front Microbiol. 2016 Aug 22;7:1289,,BcDIM5 knockout transformants showed that the hyphal growth rate and production of conidiophores and sclerotia were significantly reduced.,X Zhang 2016,2016,3 genes,Zhang-2016-Histone H3 Lysine 9 Methyltransfera,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8688,PHI:6659,UniProt,A6SIV4,GenBank,XP_001548776,,,B05.10,BcIEB1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,small secretory protein of 187 amino acids,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,YVS,27457989,PubMed,10.1016/j.plantsci.2016.06.009,Plant Sci. 2016 Sep;250:115-24,nbrito@ull.edu.es,"When BcIEB1 was applied to plant tissues it produced necrosis as well as a whole range of symptoms including inhibition of seedling growth in Arabidopsis and tobacco, ion leakage from tobacco leaf disks, a ROS burst, cell death and autofluorescence in onion epidermis, as well as the expression of defense genes in tobacco. Tobacco plants treated with BcIEB1 showed an increased systemic resistance to B. cinerea.",M Frías 2016,2016,1 gene,"Frias-2016-BcIEB1, a Botrytis cinerea secreted",BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8689,PHI:6659,UniProt,A6SIV4,GenBank,XP_001548776,,,B05.10,BcIEB1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Havana,,,leaf,small secretory protein of 187 amino acids,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,YVS,27457989,PubMed,10.1016/j.plantsci.2016.06.009,Plant Sci. 2016 Sep;250:115-24,nbrito@ull.edu.es,"When BcIEB1 was applied to plant tissues it produced necrosis as well as a whole range of symptoms including inhibition of seedling growth in Arabidopsis and tobacco, ion leakage from tobacco leaf disks, a ROS burst, cell death and autofluorescence in onion epidermis, as well as the expression of defense genes in tobacco. Tobacco plants treated with BcIEB1 showed an increased systemic resistance to B. cinerea.",M Frías 2016,2016,1 gene,"Frias-2016-BcIEB1, a Botrytis cinerea secreted",BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8690,PHI:6659,UniProt,A6SIV4,GenBank,XP_001548776,,,B05.10,BcIEB1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,small secretory protein of 187 amino acids,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene disruption,,,YVS,27457989,PubMed,10.1016/j.plantsci.2016.06.009,Plant Sci. 2016 Sep;250:115-24,nbrito@ull.edu.es,"When BcIEB1 was applied to plant tissues it produced necrosis as well as a whole range of symptoms including inhibition of seedling growth in Arabidopsis and tobacco, ion leakage from tobacco leaf disks, a ROS burst, cell death and autofluorescence in onion epidermis, as well as the expression of defense genes in tobacco. Tobacco plants treated with BcIEB1 showed an increased systemic resistance to B. cinerea.",M Frías 2016,2016,1 gene,"Frias-2016-BcIEB1, a Botrytis cinerea secreted",BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8691,PHI:6659,UniProt,A6SIV4,GenBank,XP_001548776,,,B05.10,BcIEB1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,small secretory protein of 187 amino acids,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,YVS,27457989,PubMed,10.1016/j.plantsci.2016.06.009,Plant Sci. 2016 Sep;250:115-24,nbrito@ull.edu.es,"When BcIEB1 was applied to plant tissues it produced necrosis as well as a whole range of symptoms including inhibition of seedling growth in Arabidopsis and tobacco, ion leakage from tobacco leaf disks, a ROS burst, cell death and autofluorescence in onion epidermis, as well as the expression of defense genes in tobacco. Tobacco plants treated with BcIEB1 showed an increased systemic resistance to B. cinerea.",M Frías 2016,2016,1 gene,"Frias-2016-BcIEB1, a Botrytis cinerea secreted",BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8692,PHI:6660,UniProt,Q5ANH2,GenBank,ARV1_CANAL,,,SC5314,CaArv1,,Caarv1C3S; Caarv1C28S,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,kidney; spleen; liver,regulates sterol distribution,,,,loss of pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,27587298,PubMed,10.1534/g3.116.033969,G3 (Bethesda). 2016 Aug 31. pii: g3.116.033969,jnickels@venenumbiodesign.com,The importance of the Arv1 homology domain (AHD) and zinc-binding domain in CaArv1 in fungal invasion was established and an avirulent phenotype was correlated with the inability to maintain proper sterol distribution.,P McCourt 2016,2016,1 gene,McCourt-2016-Proper Sterol Distribution Is Req,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8693,PHI:6661,UniProt,P80672,GenBank,CAL35374,,,NCTC 11168,porA,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,gastroenteritis,rodents,10141,Cavia porcellus (related: domestic guinea pig),,,,uterus; placenta,major outer membrane protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27601641,PubMed,10.1073/pnas.1605869113,Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10690-5,zhang123@iastate.edu,Specific mutations in porA are required for C. jejuni systemic infection and abortion,Z Wu 2016,2016,1 gene,Wu-2016-Point mutations in the major outer mem,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8694,PHI:6662,UniProt,Q8P801,GenBank,AAM41727,,,ATCC 33913,gumF,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain XcFC2,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,glycosyltransferases,,,xanthan biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,reduced callose deposition,gene mutation,,,YVS,27464764,PubMed,10.1094/MPMI-06-16-0106-R,Mol Plant Microbe Interact. 2016 Sep;29(9):688-699. Epub 2016 Aug 25,avojnov@fundacioncassara.org.ar,"Lack of acetylation of Man(int), pyruvilation of Man(ext), or absence of Man(ext) affect bacterial adhesion and biofilm architecture. Ketal-Pyr substituents and Man(ext) residues of xanthan molecules are required for X. campestris pv. campestris virulence in Arabidopsis thaliana plants.",M I Bianco 2016,2016,4 genes,Bianco-2016-Xanthan Pyruvilation Is Essential,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8695,PHI:6663,UniProt,Q8P802,GenBank,AAM41726,,,ATCC 33913,gumG,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain XcFC2,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,glycosyltransferases,,,xanthan biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,reduced callose deposition,gene mutation,,,YVS,27464764,PubMed,10.1094/MPMI-06-16-0106-R,Mol Plant Microbe Interact. 2016 Sep;29(9):688-699. Epub 2016 Aug 25,avojnov@fundacioncassara.org.ar,"Lack of acetylation of Man(int), pyruvilation of Man(ext), or absence of Man(ext) affect bacterial adhesion and biofilm architecture. Ketal-Pyr substituents and Man(ext) residues of xanthan molecules are required for X. campestris pv. campestris virulence in Arabidopsis thaliana plants.",M I Bianco 2016,2016,4 genes,Bianco-2016-Xanthan Pyruvilation Is Essential,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8696,PHI:6664,UniProt,Q8P806,GenBank,AAM41721,,,ATCC 33913,gumL,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain XcFC2,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,glycosyltransferases,,,xanthan biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,reduced callose deposition,gene mutation,,,YVS,27464764,PubMed,10.1094/MPMI-06-16-0106-R,Mol Plant Microbe Interact. 2016 Sep;29(9):688-699. Epub 2016 Aug 25,avojnov@fundacioncassara.org.ar,"Lack of acetylation of Man(int), pyruvilation of Man(ext), or absence of Man(ext) affect bacterial adhesion and biofilm architecture. Ketal-Pyr substituents and Man(ext) residues of xanthan molecules are required for X. campestris pv. campestris virulence in Arabidopsis thaliana plants.",M I Bianco 2016,2016,4 genes,Bianco-2016-Xanthan Pyruvilation Is Essential,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8697,PHI:6665,UniProt,Q8P804,GenBank,AAM41724,,,ATCC 33913,gumI,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain XcFC2,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,glycosyltransferases,,,xanthan biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,reduced callose deposition,gene mutation,,,YVS,27464764,PubMed,10.1094/MPMI-06-16-0106-R,Mol Plant Microbe Interact. 2016 Sep;29(9):688-699. Epub 2016 Aug 25,avojnov@fundacioncassara.org.ar,"Lack of acetylation of Man(int), pyruvilation of Man(ext), or absence of Man(ext) affect bacterial adhesion and biofilm architecture. Ketal-Pyr substituents and Man(ext) residues of xanthan molecules are required for X. campestris pv. campestris virulence in Arabidopsis thaliana plants.",M I Bianco 2016,2016,4 genes,Bianco-2016-Xanthan Pyruvilation Is Essential,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8698,PHI:6662,UniProt,Q8P801,GenBank,AAM41727,,,ATCC 33913,gumF,,,,,,PHI:6663; PHI:6664; PHI:6665,339,Xanthomonas campestris,340,pv. campestris strain XcFC2,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,glycosyltransferases,,,xanthan biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,reduced callose deposition,gene mutation,,,YVS,27464764,PubMed,10.1094/MPMI-06-16-0106-R,Mol Plant Microbe Interact. 2016 Sep;29(9):688-699. Epub 2016 Aug 25,avojnov@fundacioncassara.org.ar,"Lack of acetylation of Man(int), pyruvilation of Man(ext), or absence of Man(ext) affect bacterial adhesion and biofilm architecture. Ketal-Pyr substituents and Man(ext) residues of xanthan molecules are required for X. campestris pv. campestris virulence in Arabidopsis thaliana plants.",M I Bianco 2016,2016,4 genes,Bianco-2016-Xanthan Pyruvilation Is Essential,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8699,PHI:6663,UniProt,Q8P802,GenBank,AAM41726,,,ATCC 33913,gumG,,,,,,PHI:6662; PHI:6664; PHI:6665,339,Xanthomonas campestris,340,pv. campestris strain XcFC2,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,glycosyltransferases,,,xanthan biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,reduced callose deposition,gene mutation,,,YVS,27464764,PubMed,10.1094/MPMI-06-16-0106-R,Mol Plant Microbe Interact. 2016 Sep;29(9):688-699. Epub 2016 Aug 25,avojnov@fundacioncassara.org.ar,"Lack of acetylation of Man(int), pyruvilation of Man(ext), or absence of Man(ext) affect bacterial adhesion and biofilm architecture. Ketal-Pyr substituents and Man(ext) residues of xanthan molecules are required for X. campestris pv. campestris virulence in Arabidopsis thaliana plants.",M I Bianco 2016,2016,4 genes,Bianco-2016-Xanthan Pyruvilation Is Essential,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8700,PHI:6664,UniProt,Q8P806,GenBank,AAM41721,,,ATCC 33913,gumL,,,,,,PHI:6662; PHI:6663; PHI:6665,339,Xanthomonas campestris,340,pv. campestris strain XcFC2,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,glycosyltransferases,,,xanthan biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,reduced callose deposition,gene mutation,,,YVS,27464764,PubMed,10.1094/MPMI-06-16-0106-R,Mol Plant Microbe Interact. 2016 Sep;29(9):688-699. Epub 2016 Aug 25,avojnov@fundacioncassara.org.ar,"Lack of acetylation of Man(int), pyruvilation of Man(ext), or absence of Man(ext) affect bacterial adhesion and biofilm architecture. Ketal-Pyr substituents and Man(ext) residues of xanthan molecules are required for X. campestris pv. campestris virulence in Arabidopsis thaliana plants.",M I Bianco 2016,2016,4 genes,Bianco-2016-Xanthan Pyruvilation Is Essential,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8701,PHI:6665,UniProt,Q8P804,GenBank,AAM41724,,,ATCC 33913,gumI,,,,,,PHI:6662; PHI:6663; PHI:6664,339,Xanthomonas campestris,340,pv. campestris strain XcFC2,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,glycosyltransferases,,,xanthan biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,reduced callose deposition,gene mutation,,,YVS,27464764,PubMed,10.1094/MPMI-06-16-0106-R,Mol Plant Microbe Interact. 2016 Sep;29(9):688-699. Epub 2016 Aug 25,avojnov@fundacioncassara.org.ar,"Lack of acetylation of Man(int), pyruvilation of Man(ext), or absence of Man(ext) affect bacterial adhesion and biofilm architecture. Ketal-Pyr substituents and Man(ext) residues of xanthan molecules are required for X. campestris pv. campestris virulence in Arabidopsis thaliana plants.",M I Bianco 2016,2016,4 genes,Bianco-2016-Xanthan Pyruvilation Is Essential,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8702,PHI:6666,UniProt,P0C7Y0,GenBank,PSMA1_STAA3,,,USA300,PSMa1,,,,,,PHI:6667; PHI:6668; PHI:6669,1280,Staphylococcus aureus,367830,USA300,sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood,phenol-soluble modulin alpha peptide involved in mobilizing lipoproteins,,,TLR2 pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27470911,PubMed,10.1038/ncomms12304,Nat Commun. 2016 Jul 29;7:12304,dorothee.kretschmer@uni-tuebingen.de,"Strong TLR2 stimulation depends on high-level production of phenol-soluble modulin (PSM) peptides in response to the global virulence activator Agr. PSMs are required for mobilizing lipoproteins, the TLR2 agonists, from the staphylococcal cytoplasmic membrane.",D Hanzelmann 2016,2016,4 genes,Hanzelmann-2016-Toll-like receptor 2 activatio,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8703,PHI:6667,UniProt,P0C7Z2,GenBank,PSMA2_STAA3,,,USA300,PSMa2,,,,,,PHI:6666; PHI:6668; PHI:6669,1280,Staphylococcus aureus,367830,USA300,sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood,phenol-soluble modulin alpha peptide involved in mobilizing lipoproteins,,,TLR2 pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27470911,PubMed,10.1038/ncomms12304,Nat Commun. 2016 Jul 29;7:12304,dorothee.kretschmer@uni-tuebingen.de,"Strong TLR2 stimulation depends on high-level production of phenol-soluble modulin (PSM) peptides in response to the global virulence activator Agr. PSMs are required for mobilizing lipoproteins, the TLR2 agonists, from the staphylococcal cytoplasmic membrane.",D Hanzelmann 2016,2016,4 genes,Hanzelmann-2016-Toll-like receptor 2 activatio,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8704,PHI:6668,UniProt,P0C804,GenBank,PSMA3_STAA3,,,USA300,PSMa3,,,,,,PHI:6666; PHI:6667; PHI:6669,1280,Staphylococcus aureus,367830,USA300,sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood,phenol-soluble modulin alpha peptide involved in mobilizing lipoproteins,,,TLR2 pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27470911,PubMed,10.1038/ncomms12304,Nat Commun. 2016 Jul 29;7:12304,dorothee.kretschmer@uni-tuebingen.de,"Strong TLR2 stimulation depends on high-level production of phenol-soluble modulin (PSM) peptides in response to the global virulence activator Agr. PSMs are required for mobilizing lipoproteins, the TLR2 agonists, from the staphylococcal cytoplasmic membrane.",D Hanzelmann 2016,2016,4 genes,Hanzelmann-2016-Toll-like receptor 2 activatio,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8705,PHI:6669,UniProt,P0C817,GenBank,PSMA4_STAA3,,,USA300,PSMa4,,,,,,PHI:6666; PHI:6667; PHI:6668,1280,Staphylococcus aureus,367830,USA300,sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood,phenol-soluble modulin alpha peptide involved in mobilizing lipoproteins,,,TLR2 pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27470911,PubMed,10.1038/ncomms12304,Nat Commun. 2016 Jul 29;7:12304,dorothee.kretschmer@uni-tuebingen.de,"Strong TLR2 stimulation depends on high-level production of phenol-soluble modulin (PSM) peptides in response to the global virulence activator Agr. PSMs are required for mobilizing lipoproteins, the TLR2 agonists, from the staphylococcal cytoplasmic membrane.",D Hanzelmann 2016,2016,4 genes,Hanzelmann-2016-Toll-like receptor 2 activatio,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8706,PHI:6670,UniProt,Q4WJD1,GenBank,EAL88351,,,Af293,SchA,chromosome 1,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,"ser/Thr kinase of AGC family (the cAMP-dependent PKA, cGMP dependent protein kinase G and phospholipid-dependent protein kinase C family)",,,HOG and calcium-calcineurin/CrzA pathways,loss of pathogenicity,,,,,,,,,,no,NaCl; sorbitol; CaCl2; MnCl2; fludioxonil; iprodione; caspofungin; echinocandin; rapamycin; myriocin; aureobasidin A,"NaCl: CHEBI:26710; sorbitol: CHEBI:30911; CaCl2: CHEBI:3312; MnCl2: CHEBI:63041; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; caspofungin: CHEBI:474180; echinocandin: CHEBI:57248; rapamycin: CHEBI:9168; l,  myriocin: CHEBI:582124; aureobasidin A: CHEBI:61739",,,,,gene deletion: full; gene complementation,,,YVS,27538790,PubMed,10.1111/mmi.13484,Mol Microbiol. 2016 Nov;102(4):642-671,ggoldman@usp.br,The double mutants DeltaschA DeltasakA and DeltaschA DeltampkC were more sensitive to osmotic stress than the corresponding parental strains.,P A de Castro 2016,2016,1 gene,Alves de Castro-2016-The Aspergillus fumigatus,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8707,PHI:6670,UniProt,Q4WJD1,GenBank,EAL88351,,,Af293,SchA,chromosome 1,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,"ser/Thr kinase of AGC family (the cAMP-dependent PKA, cGMP dependent protein kinase G and phospholipid-dependent protein kinase C family)",,,HOG and calcium-calcineurin/CrzA pathways,loss of pathogenicity,,,,,,,,,,no,NaCl; sorbitol; CaCl2; MnCl2; fludioxonil; iprodione; caspofungin; echinocandin; rapamycin; myriocin; aureobasidin A,"NaCl: CHEBI:26710; sorbitol: CHEBI:30911; CaCl2: CHEBI:3312; MnCl2: CHEBI:63041; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; caspofungin: CHEBI:474180; echinocandin: CHEBI:57248; rapamycin: CHEBI:9168; l,  myriocin: CHEBI:582124; aureobasidin A: CHEBI:61739",,,,,gene deletion: full; gene complementation,,,YVS,27538790,PubMed,10.1111/mmi.13484,Mol Microbiol. 2016 Nov;102(4):642-671,ggoldman@usp.br,The double mutants DeltaschA DeltasakA and DeltaschA DeltampkC were more sensitive to osmotic stress than the corresponding parental strains.,P A de Castro 2016,2016,1 gene,Alves de Castro-2016-The Aspergillus fumigatus,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8708,PHI:6671,UniProt,Q59X67,GenBank,EFG1_CANAL,,,SC5314,Efg1,,,,,,,5476,Candida albicans,,DAY185,denture stomatitis,rodents,10114,Rattus (related: rat),,,,palate,transcription factors,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27453977,PubMed,10.1371/journal.pone.0159692,PLoS One. 2016 Jul 25;11(7):e0159692,mnover@lsuhsc.edu,"Biofilm formation is associated with tissue damage during DS and that Efg1 and Bcr1, both central regulators of virulence in C. albicans, have pivotal roles in pathogenesis of DS.",J Yano 2016,2016,2 genes,Yano-2016-Transcription Factors Efg1 and Bcr1,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8709,PHI:6672,UniProt,Q59U10,GenBank,BCR1_CANAL,,,SC5314,Bcr1,,,,,,,5476,Candida albicans,,DAY185,denture stomatitis,rodents,10114,Rattus (related: rat),,,,palate,transcription factors,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27453977,PubMed,10.1371/journal.pone.0159692,PLoS One. 2016 Jul 25;11(7):e0159692,mnover@lsuhsc.edu,"Biofilm formation is associated with tissue damage during DS and that Efg1 and Bcr1, both central regulators of virulence in C. albicans, have pivotal roles in pathogenesis of DS.",J Yano 2016,2016,2 genes,Yano-2016-Transcription Factors Efg1 and Bcr1,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8710,PHI:6673,UniProt,A0A0H3JRA8,GenBank,BAB57484,,,Mu50,SAV1322,,,,,,,1280,Staphylococcus aureus,158878,Mu50,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; kidney,two-component response regulator,,,,reduced virulence,,,,,,,,wild type,,no,vancomycin; daptomycin; gentamicin; erythromycin; tigecycline; imipenem; linezolid; oxacillin; penicillin; teicoplanin; tetracycline; H2O2,vancomycin: CHEBI:28001; daptomycin: CHEBI:600103; gentamicin: CHEBI:17833; erythromycin: CHEBI:48923; tigecycline: CHEBI:149836; imipenem: CHEBI:471744; linezolid: CHEBI:63607; oxacillin: CHEBI:7809; penicillin: CHEBI:17334; teicoplanin: CHEBI:29687; tetracycline: CHEBI:27902; H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,27599615,PubMed,10.1186/s12866-016-0824-2,BMC Microbiol. 2016 Sep 6;16(1):206,knihyoo@naver.com,"S. aureus SAV1322 locus plays a pronounced role in temperature adaptation, antibiotic resistance and virulence by regulating a wide range of genes and proteins involved in metabolism and stress tolerance.",J W Kim 2016,2016,1 gene,Kim-2016-The SAV1322 gene from Staphylococcus,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8711,PHI:6674,UniProt,G4MY64,GenBank,EHA54395,,,70-15,MoTRX2,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"thioredoxin oxidoreductase, a target of MoAP1 transcription factor governing oxidative response",,,,reduced virulence,yes,,,yes,,reduced,reduced,reduced; aberrant,,no,diphenyleneiodonium,diphenyleneiodonium: CHEBI:77986,,,,,gene deletion: full; gene complementation,,,YVS,27560036,PubMed,10.1111/mpp.12484,Mol Plant Pathol. 2016 Aug 25,zhgzhang@njau.edu.cn,"DeltaMotrx2 mutants display higher intracellular ROS levels during conidial germination, but lower peroxidase and laccase activities, which contribute to the attenuation in virulence.",J Wang 2016,2016,1 gene,Wang-2016-The thioredoxin MoTrx2 protein media,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8712,PHI:6675,UniProt,Q52BY4,GenBank,EHA55375,,,70-15,MoMBF1,,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,"multiprotein bridging factor 1, a transcriptional co-activator",,,,reduced virulence,,no,yes,yes,,wild type,,reduced,wild type,no,D-sorbitol; H2O2; NaCl,D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,27485943,PubMed,10.1007/s00294-016-0636-9,Curr Genet. 2016 Aug 2,gdlufafu@163.com,"MoMBF1 is required for vegetative growth, pathogenicity and stress response in M. oryzae.",G Fan 2016,2016,1 gene,Fan-2016-Multiprotein-bridging factor 1 regula,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8713,PHI:6676,UniProt,G4PE73,GenBank,AEQ07639,,,NI,yejA1,chromosome I,,,,,PHI:6677; PHI:6678; PHI:6679; PHI:6680,29459,Brucella melitensis,1029825,NI,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,putative extracellular solute-binding protein,,,,loss of pathogenicity,,,,,,,,wild type,,no,polymyxin B,polymixin B: CHEBI:8310,,,,,gene mutation,,,YVS,27550726,PubMed,10.1038/srep31876,Sci Rep. 2016 Aug 23;6:31876,wuqm@cau.edu.cn,YejABEF proteins contribute to resistance to acidic conditions. Deletion of the yejE gene confers susceptibility to polymyxin B.,Z Wang 2016,2016,4 genes,Wang-2016-The ABC transporter YejABEF is requi,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8714,PHI:6677,UniProt,G4PE72,GenBank,AEQ07638,,,NI,yejA2,chromosome I,,,,,PHI:6676; PHI:6678; PHI:6679; PHI:6680,29459,Brucella melitensis,1029825,NI,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,putative extracellular solute-binding protein,,,,loss of pathogenicity,,,,,,,,wild type,,no,polymyxin B,polymixin B: CHEBI:8310,,,,,gene mutation,,,YVS,27550726,PubMed,10.1038/srep31876,Sci Rep. 2016 Aug 23;6:31876,wuqm@cau.edu.cn,YejABEF proteins contribute to resistance to acidic conditions. Deletion of the yejE gene confers susceptibility to polymyxin B.,Z Wang 2016,2016,4 genes,Wang-2016-The ABC transporter YejABEF is requi,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8715,PHI:6678,UniProt,G4PE71,GenBank,AEQ07637,,,NI,yejB,chromosome I,,,,,PHI:6676; PHI:6677; PHI:6679; PHI:6680,29459,Brucella melitensis,1029825,NI,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,transport system permease component,,,,loss of pathogenicity,,,,,,,,wild type,,no,polymyxin B,polymixin B: CHEBI:8310,,,,,gene mutation,,,YVS,27550726,PubMed,10.1038/srep31876,Sci Rep. 2016 Aug 23;6:31876,wuqm@cau.edu.cn,YejABEF proteins contribute to resistance to acidic conditions. Deletion of the yejE gene confers susceptibility to polymyxin B.,Z Wang 2016,2016,4 genes,Wang-2016-The ABC transporter YejABEF is requi,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8716,PHI:6679,,no data found,GenBank,AEQ07636,,,NI,yejE,chromosome I,,,,,PHI:6676; PHI:6677; PHI:6678; PHI:6680,29459,Brucella melitensis,1029825,NI,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,transport system permease component,,,,loss of pathogenicity,,,,,,,,wild type,,no,polymyxin B,polymixin B: CHEBI:8310,,,,,gene mutation,,,YVS,27550726,PubMed,10.1038/srep31876,Sci Rep. 2016 Aug 23;6:31876,wuqm@cau.edu.cn,YejABEF proteins contribute to resistance to acidic conditions. Deletion of the yejE gene confers susceptibility to polymyxin B.,Z Wang 2016,2016,4 genes,Wang-2016-The ABC transporter YejABEF is requi,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8717,PHI:6680,UniProt,G4PE69,GenBank,AEQ07635,,,NI,yejF,chromosome I,,,,,PHI:6676; PHI:6677; PHI:6678; PHI:6679,29459,Brucella melitensis,1029825,NI,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,ABC transporter system ATP-binding protein,,,,loss of pathogenicity,,,,,,,,wild type,,no,polymyxin B,polymixin B: CHEBI:8310,,,,,gene mutation,,,YVS,27550726,PubMed,10.1038/srep31876,Sci Rep. 2016 Aug 23;6:31876,wuqm@cau.edu.cn,YejABEF proteins contribute to resistance to acidic conditions. Deletion of the yejE gene confers susceptibility to polymyxin B.,Z Wang 2016,2016,4 genes,Wang-2016-The ABC transporter YejABEF is requi,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8718,PHI:6679,,no data found,GenBank,AEQ07636,,,NI,yejE,chromosome I,,,,,,29459,Brucella melitensis,1029825,NI,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,transport system permease component,,,,loss of pathogenicity,,,,,,,,wild type,,no,polymyxin B,polymixin B: CHEBI:8310,,,,,gene mutation; gene complementation,,,YVS,27550726,PubMed,10.1038/srep31876,Sci Rep. 2016 Aug 23;6:31876,wuqm@cau.edu.cn,YejABEF proteins contribute to resistance to acidic conditions. Deletion of the yejE gene confers susceptibility to polymyxin B.,Z Wang 2016,2016,4 genes,Wang-2016-The ABC transporter YejABEF is requi,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8719,PHI:6681,UniProt,K9FEW0,GenBank,EKV07940,,,PHI26,Pdac1,,,,,,,36651,Penicillium digitatum,1170229,PHI26,green mold (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,fruit,adenylyl cyclase,,,cAMP-mediated signaling pathway,reduced virulence,,,,,,increased,,reduced,reduced,no,,,,,,,gene disruption,,,YVS,27664719,PubMed,10.1016/j.micres.2016.05.013,Microbiol Res. 2016 Nov;192:11-20,hyli@zju.edu.cn,"Fungal mutants lacking Pdac1 produced abundant conidia, which failed to germinate effectively and displayed an elevated sensitivity to heat treatment. Pdac1 mutant failed to utilize carbohydrates effectively and thus displayed severe growth retardation on rich and synthetic media.",W Wang 2016,2016,1 gene,Wang-2016-Adenylyl cyclase is required for cAM,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8720,PHI:6682,UniProt,A0A160YF90,GenBank,CZR74664,,,CD105KSE1,agr1,,,,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,toxin production and virulence,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,RP,27531912,PubMed,10.1128/mBio.01237-16,MBio. 2016 Aug 16;7(4). pii: e01237-16,Charles.darkoh@uth.tmc.edu,"The agr1 mutant cannot produce toxins A and B; toxin production can be restored by complementation with wild-type agr1. Furthermore, the agr1 mutant is able to colonize but unable to cause disease in a murine model. Pathogen formerly called Clostridium difficile",C Darkoh 2016,2016,1 gene,Darkoh-2016-Accessory Gene Regulator-1 Locus I,BATCH_063B,2016-12-01,MC,,,,,,,,,,,,,
,,Record 8721,PHI:6182,UniProt,B2SU53,GenBank,AY495676,,,PXO99A,pthXo1,,re-introduction of pthXo1 into pthXo1 minus strain PXO99AME2,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,contains Xa5 (Recessive resistance gene),UniProt: B7EAK7; GenBank: AEP20535,leaf,transcription activation-like (TAL) effector gene,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,return to susceptible,,functional test in host,,,RP,26991395,PubMed,10.1111/tpj.13164,Plant J. 2016 Apr;86(2):186-94,ffwhite@ufl.edu,"xa5 functions as a quantitative trait locus, dampening effector function and, regardless of compatibility, target gene expression. Xa5 is a recessive resistance gene and challenge with pthXo1 containing strain results in compatibility (disease).",S Huang 2016,2016,1 gene,Huang-2016-The broadly effective recessive res,BATCH_058B,2016-05-01,MC,,,,,,,,,,,,,
,,Record 8722,PHI:6683,UniProt,B8NSU9,GenBank,EED47088,,,NRRL3357,AflgcnE,,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,histone acetyltransferase,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,NaCl; KCl; Congo red; calcofluor; tert-butyl hydroperoxide (tBOOH); hydroxyurea; methyl methanesulfonate; H2O2,NaCl: CHEBI:26710; KCl: CHEBI:32588; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; tert-butyl hydroperoxide (tBOOH): CHEBI:64090; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,27625637,PubMed,10.3389/fmicb.2016.01324,Front Microbiol. 2016 Aug 30;7:1324,wshyyl@sina.com,"Deletion of AflgcnE inhibited the growth of A. flavus and decreased the hydrophobicity of the cell surface. The AflgcnE mutant exhibited a lack of asexual sporulation, was unable to generate sclerotia and did not produce alfatoxins, which was consistent with a significant downregulation of alfatoxin gene expression levels. Additionally, AflgcnE was required to maintain cell wall integrity and genotoxic stress responses.",H Lan 2016,2016,1 gene,Lan-2016-The Aspergillus flavus Histone Acetyl,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8723,PHI:6684,UniProt,Q2YRY5,GenBank,CAJ11717,,,2308,pyk,chromosome I,,,,,,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,pyruvate kinase,,,glycolysis pathway,reduced virulence,,,,,,,,,,no,H2O2; polymixin B,H2O2: CHEBI:16240; polymixin B: CHEBI:8310,,,,,gene mutation; gene complementation,,,YVS,27561260,PubMed,10.1186/s13567-016-0372-7,Vet Res.2016 Aug 25;47(1):87,yus@shvri.ac.cn,"Pyk plays an important role in B. abortus growth, especially under the conditions of nutrition deprivation, and resistance to oxidative stress. Pyk is necessary for B. abortus survival and evading fusion with lysosomes.",J Gao 2016,2016,1 gene,Gao-2016-Pyruvate kinase is necessary for Bruc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8724,PHI:6685,UniProt,Q9PID1,GenBank,YP_002343808,,,NCTC 11168,cj0371,,cj0371::cmr,,,,,197,Campylobacter jejuni,192222,NCTC 11168,campylobacteriosis; gastroenteritis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,cecum; colon,virulence-associated gene,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene disruption; gene complementation,,,YVS,27471500,PubMed,10.3389/fmicb.2016.01094,Front Microbiol. 2016 Jul 14;7:1094,jinlin@yzu.edu.cn,"cj0371 Mutant displays hypermotility, enhanced chemotaxis and enhanced growth kinetics.",X Du 2016,2016,1 gene,Du-2016-cj0371_ A Novel Virulence-Associated G,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8725,PHI:6686,UniProt,A0A125YRV6,GenBank,EPR64742,,,GT1,gra1,chromosome VIII,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8726,PHI:6687,UniProt,S7V5D0,GenBank,EPR64872,,,GT1,gra10,chromosome VIII,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8727,PHI:6688,UniProt,S7UXS8,GenBank,EPR62387,,,GT1,gra2,chromosome X,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8728,PHI:6689,UniProt,A0A125YJQ7,GenBank,EPR62304,,,GT1,gra3,chromosome X,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8729,PHI:6690,UniProt,S7UT91,GenBank,EPR61166,,,GT1,gra4,chromosome XI,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8730,PHI:6691,UniProt,A0A125YQQ2,GenBank,EPR59442,,,GT1,gra5,chromosome V,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8731,PHI:6692,UniProt,S7UQL8,GenBank,EPR60010,,,GT1,gra6,chromosome X,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8732,PHI:6693,UniProt,A0A125YVB8,GenBank,EPR61672,,,GT1,gra7,chromosome VIIa,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8733,PHI:6694,UniProt,A0A125YYI5,GenBank,EPR59113,,,GT1,gra8,chromosome III,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8734,PHI:6695,UniProt,A0A125YWK4,GenBank,EPR63320,,,GT1,gra9,chromosome XII,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8735,PHI:6689,UniProt,A0A125YJQ7,GenBank,EPR62304,,,GT1,gra3,chromosome X,,,,,PHI:6691,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8736,PHI:6691,UniProt,A0A125YQQ2,GenBank,EPR59442,,,GT1,gra5,chromosome V,,,,,PHI:6689,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8737,PHI:6689,UniProt,A0A125YJQ7,GenBank,EPR62304,,,GT1,gra3,chromosome X,,,,,PHI:6693,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8738,PHI:6693,UniProt,A0A125YVB8,GenBank,EPR61672,,,GT1,gra7,chromosome VIIa,,,,,PHI:6689,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8739,PHI:6688,UniProt,S7UXS8,GenBank,EPR62387,,,GT1,gra2,chromosome X,,,,,PHI:6690,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8740,PHI:6690,UniProt,S7UT91,GenBank,EPR61166,,,GT1,gra4,chromosome XI,,,,,PHI:6688,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8741,PHI:6688,UniProt,S7UXS8,GenBank,EPR62387,,,GT1,gra2,chromosome X,,,,,PHI:6692,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8742,PHI:6692,UniProt,S7UQL8,GenBank,EPR60010,,,GT1,gra6,chromosome X,,,,,PHI:6688,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8743,PHI:6690,UniProt,S7UT91,GenBank,EPR61166,,,GT1,gra4,chromosome XI,,,,,PHI:6692,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8744,PHI:6692,UniProt,S7UQL8,GenBank,EPR60010,,,GT1,gra6,chromosome X,,,,,PHI:6690,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27458822,PubMed,10.1371/journal.pone.0159306,PLoS One.2016 Jul 26;11(7):e0159306,David.J.Bzik@dartmouth.edu,Deletion of GRA2-9 does not affect acute infection or virulence in vivo,L M Rommereim 2016,2016,10 genes,Rommereim-2016-Phenotypes Associated with Knoc,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8745,PHI:6696,UniProt,A0A0D5SDQ0,GenBank,AJZ41372,,,5208,pel3,,,,,,,346,Xanthomonas citri,611301,subsp. citri strain XW19,canker (Citrus),eudicots,159033,Citrus x aurantiifolia (related: lime),,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,YVS,27664718,PubMed,10.1016/j.micres.2016.05.011,Microbiol Res.2016 Nov;192:1-10,Kctzeng@nchu.edu.tw,"Pel3 mutant displayed reduced growth and induced smaller canker lesions on the leaves of Mexican lime, demonstrating that Pel3 of Xcc strain XW19 is a virulence factor.",S C Chang 2016,2016,1 gene,Chang-2016-Differential expression of pectolyt,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8746,PHI:6697,UniProt,A0A0U1J4N7,GenBank,CNQ39570,,,CH43,yqiC,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,cervical adenocarcinoma cell line,membrane fusogenic activity,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene disruption; gene complementation,,,YVS,27777572,PubMed,10.3389/fmicb.2016.01614,Front Microbiol.2016 Oct 10;7:1614. eCollection 2016,sbfang@tmu.edu.tw,"The phenotype of yqiC mutant exhibited few and short flagella, fimbriae on the cell surface, enhanced biofilm formation, upregulated type-1 fimbriae expression and reduced bacterial motility.",K C Wang 2016,2016,1 gene,Wang-2016-Role of yqiC in the Pathogenicity of,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8747,PHI:6697,UniProt,A0A0U1J4N7,GenBank,CNQ39570,,,CH43,yqiC,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic cancer cell line,membrane fusogenic activity,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene disruption; gene complementation,,,YVS,27777572,PubMed,10.3389/fmicb.2016.01614,Front Microbiol.2016 Oct 10;7:1614. eCollection 2016,sbfang@tmu.edu.tw,"The phenotype of yqiC mutant exhibited few and short flagella, fimbriae on the cell surface, enhanced biofilm formation, upregulated type-1 fimbriae expression and reduced bacterial motility.",K C Wang 2016,2016,1 gene,Wang-2016-Role of yqiC in the Pathogenicity of,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8748,PHI:6697,UniProt,A0A0U1J4N7,GenBank,CNQ39570,,,CH43,yqiC,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,membrane fusogenic activity,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene disruption; gene complementation,,,YVS,27777572,PubMed,10.3389/fmicb.2016.01614,Front Microbiol.2016 Oct 10;7:1614. eCollection 2016,sbfang@tmu.edu.tw,"The phenotype of yqiC mutant exhibited few and short flagella, fimbriae on the cell surface, enhanced biofilm formation, upregulated type-1 fimbriae expression and reduced bacterial motility.",K C Wang 2016,2016,1 gene,Wang-2016-Role of yqiC in the Pathogenicity of,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8749,PHI:6697,UniProt,A0A0U1J4N7,GenBank,CNQ39570,,,CH43,yqiC,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),LS174T cell line,,,colonic cancer cell line,membrane fusogenic activity,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene disruption; gene complementation,,,YVS,27777572,PubMed,10.3389/fmicb.2016.01614,Front Microbiol.2016 Oct 10;7:1614. eCollection 2016,sbfang@tmu.edu.tw,"The phenotype of yqiC mutant exhibited few and short flagella, fimbriae on the cell surface, enhanced biofilm formation, upregulated type-1 fimbriae expression and reduced bacterial motility.",K C Wang 2016,2016,1 gene,Wang-2016-Role of yqiC in the Pathogenicity of,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8750,PHI:6698,UniProt,A0A0H6NEI3,GenBank,CSB90785,,,A232,edd,,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,6-phosphogluconate dehydratase,,,entner-Doudoroff pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27650573,PubMed,10.1093/femspd/ftw085,Pathog Dis. 2016 Nov;74(8). pii: ftw085. Epub 2016 Sep 19,nandyrk@icmr.org.in,Growth defect of mutants in Gnt-supplemented media confirmed obligate involvement of these genes in Gnt utilization and defective Gnt utilization resulted in attenuation of colonization potential and reduction of cholera toxin secretion in V. cholerae. The ED pathway mutants showed the highest level of virulence attenuation.,S Roy 2016,2016,5 genes,Roy-2016-Characterization of the gluconate uti,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8751,PHI:6698,UniProt,A0A0H6NEI3,GenBank,CSB90785,,,A232,edd,,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,intestine,6-phosphogluconate dehydratase,,,entner-Doudoroff pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27650573,PubMed,10.1093/femspd/ftw085,Pathog Dis. 2016 Nov;74(8). pii: ftw085. Epub 2016 Sep 19,nandyrk@icmr.org.in,Growth defect of mutants in Gnt-supplemented media confirmed obligate involvement of these genes in Gnt utilization and defective Gnt utilization resulted in attenuation of colonization potential and reduction of cholera toxin secretion in V. cholerae. The ED pathway mutants showed the highest level of virulence attenuation.,S Roy 2016,2016,5 genes,Roy-2016-Characterization of the gluconate uti,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8752,PHI:6699,UniProt,A0A0H6T2F5,GenBank,AKO73834,,,TSY216,eda,chromosome 1,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,2-keto-3-deoxy-6-phosphogluconate aldolase,,,entner-Doudoroff pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27650573,PubMed,10.1093/femspd/ftw085,Pathog Dis. 2016 Nov;74(8). pii: ftw085. Epub 2016 Sep 19,nandyrk@icmr.org.in,Growth defect of mutants in Gnt-supplemented media confirmed obligate involvement of these genes in Gnt utilization and defective Gnt utilization resulted in attenuation of colonization potential and reduction of cholera toxin secretion in V. cholerae. The ED pathway mutants showed the highest level of virulence attenuation.,S Roy 2016,2016,5 genes,Roy-2016-Characterization of the gluconate uti,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8753,PHI:6699,UniProt,A0A0H6T2F5,GenBank,AKO73834,,,TSY216,eda,chromosome 1,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,intestine,2-keto-3-deoxy-6-phosphogluconate aldolase,,,entner-Doudoroff pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27650573,PubMed,10.1093/femspd/ftw085,Pathog Dis. 2016 Nov;74(8). pii: ftw085. Epub 2016 Sep 19,nandyrk@icmr.org.in,Growth defect of mutants in Gnt-supplemented media confirmed obligate involvement of these genes in Gnt utilization and defective Gnt utilization resulted in attenuation of colonization potential and reduction of cholera toxin secretion in V. cholerae. The ED pathway mutants showed the highest level of virulence attenuation.,S Roy 2016,2016,5 genes,Roy-2016-Characterization of the gluconate uti,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8754,PHI:6700,UniProt,A0A0H3Q531,GenBank,EEO18541,,,B33,gntU,,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,low-affinity permease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27650573,PubMed,10.1093/femspd/ftw085,Pathog Dis. 2016 Nov;74(8). pii: ftw085. Epub 2016 Sep 19,nandyrk@icmr.org.in,Growth defect of mutants in Gnt-supplemented media confirmed obligate involvement of these genes in Gnt utilization and defective Gnt utilization resulted in attenuation of colonization potential and reduction of cholera toxin secretion in V. cholerae. The ED pathway mutants showed the highest level of virulence attenuation.,S Roy 2016,2016,5 genes,Roy-2016-Characterization of the gluconate uti,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8755,PHI:6700,UniProt,A0A0H3Q531,GenBank,EEO18541,,,B33,gntU,,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,intestine,low-affinity permease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27650573,PubMed,10.1093/femspd/ftw085,Pathog Dis. 2016 Nov;74(8). pii: ftw085. Epub 2016 Sep 19,nandyrk@icmr.org.in,Growth defect of mutants in Gnt-supplemented media confirmed obligate involvement of these genes in Gnt utilization and defective Gnt utilization resulted in attenuation of colonization potential and reduction of cholera toxin secretion in V. cholerae. The ED pathway mutants showed the highest level of virulence attenuation.,S Roy 2016,2016,5 genes,Roy-2016-Characterization of the gluconate uti,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8756,PHI:6701,UniProt,A0A0H6FRN3,GenBank,CSB09787,,,A51,gntK,,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,thermo-resistant gluconate kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27650573,PubMed,10.1093/femspd/ftw085,Pathog Dis. 2016 Nov;74(8). pii: ftw085. Epub 2016 Sep 19,nandyrk@icmr.org.in,Growth defect of mutants in Gnt-supplemented media confirmed obligate involvement of these genes in Gnt utilization and defective Gnt utilization resulted in attenuation of colonization potential and reduction of cholera toxin secretion in V. cholerae. The ED pathway mutants showed the highest level of virulence attenuation.,S Roy 2016,2016,5 genes,Roy-2016-Characterization of the gluconate uti,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8757,PHI:6701,UniProt,A0A0H6FRN3,GenBank,CSB09787,,,A51,gntK,,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,intestine,thermo-resistant gluconate kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27650573,PubMed,10.1093/femspd/ftw085,Pathog Dis. 2016 Nov;74(8). pii: ftw085. Epub 2016 Sep 19,nandyrk@icmr.org.in,Growth defect of mutants in Gnt-supplemented media confirmed obligate involvement of these genes in Gnt utilization and defective Gnt utilization resulted in attenuation of colonization potential and reduction of cholera toxin secretion in V. cholerae. The ED pathway mutants showed the highest level of virulence attenuation.,S Roy 2016,2016,5 genes,Roy-2016-Characterization of the gluconate uti,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8758,PHI:6702,UniProt,A5F6Z2,GenBank,ABQ21763,,,O395,gntR,chromosome 2,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,regulatory molecule,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27650573,PubMed,10.1093/femspd/ftw085,Pathog Dis. 2016 Nov;74(8). pii: ftw085. Epub 2016 Sep 19,nandyrk@icmr.org.in,Growth defect of mutants in Gnt-supplemented media confirmed obligate involvement of these genes in Gnt utilization and defective Gnt utilization resulted in attenuation of colonization potential and reduction of cholera toxin secretion in V. cholerae. The ED pathway mutants showed the highest level of virulence attenuation.,S Roy 2016,2016,5 genes,Roy-2016-Characterization of the gluconate uti,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8759,PHI:6702,UniProt,A5F6Z2,GenBank,ABQ21763,,,O395,gntR,chromosome 2,,,,,,666,Vibrio cholerae,243277,serotype O1 biovar El Tor strain N16961,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,intestine,regulatory molecule,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27650573,PubMed,10.1093/femspd/ftw085,Pathog Dis. 2016 Nov;74(8). pii: ftw085. Epub 2016 Sep 19,nandyrk@icmr.org.in,Growth defect of mutants in Gnt-supplemented media confirmed obligate involvement of these genes in Gnt utilization and defective Gnt utilization resulted in attenuation of colonization potential and reduction of cholera toxin secretion in V. cholerae. The ED pathway mutants showed the highest level of virulence attenuation.,S Roy 2016,2016,5 genes,Roy-2016-Characterization of the gluconate uti,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8760,PHI:6703,UniProt,T0LLS6,GenBank,EQB52656,,,Cg-14,CgRhoB,,,,,,,474922,Colletotrichum gloeosporioides,,CFCC80308,anthracnose (poplar),eudicots,1217306,Populus x beijingensis (no common name found),,,,leaf,Rho GTPase protein,,,,reduced virulence,,yes,,,,reduced,,reduced,reduced; aberrant,no,calcofluor white; congo red; NaCl; H2O2; sorbitol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; NaCl: CHEBI:26710; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene disruption; gene complementation,,,YVS,27670809,PubMed,10.1016/j.fgb.2016.09.002,Fungal Genet Biol.2016 Sep 23;96:12-24,liangym@bjfu.edu.cn,Deletion of CgRhoB had discernible effect upon the sensitivity of C. gloeosporioides to cell wall perturbing agents and altered the distribution of chitin on the cell wall.,X Xu 2016,2016,1 gene,Xu-2016-The Colletotrichum gloeosporioides Rho,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8761,PHI:6705,UniProt,A0A0H2Z644,GenBank,ABJ03844,,,APEC O1,ibeA,,,,,,,562,Escherichia coli,1392869,K1 ZD1,neonatal sepsis; neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),,Vimentin (NF-kappaB regulator)(gene mutation vim-),UniProt: P20152; GenBank: AAA40555,brain; blood,invasion protein,,,NF-kappaB signaling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27657497,PubMed,10.1371/journal.pone.0162641,PLoS One. 2016 Sep 22;11(9):e0162641,shhuang@usc.edu,"IbeA-induced NF-kappaB activation, E. coli K1 invasion and polymorphonuclear neutrophil (PMN) transmigration across the BBB were significantly reduced in Vim-/-mice.",S H Huang 2016,2016,2 genes,"Huang-2016-Vimentin, a Novel NF-kappaB Regulat",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8762,PHI:6706,UniProt,A0A160EFI3,GenBank,ANB45613,,,APCE01,eivC,,,,,,,562,Escherichia coli,,APCE94,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),,,,liver; spleen; lung; blood,type III secretion system 2 ATPase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27630634,PubMed,10.3389/fmicb.2016.01387,Front Microbiol. 2016 Aug 31;7:1387,yus@shvri.ac.cn,Inactivation of eivC led to impaired flagella production and augmented fimbriae on the bacterial surface and consequently reduced bacterial motility.,S Wang 2016,2016,1 gene,Wang-2016-Escherichia coli Type III Secretion,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8763,PHI:6708,UniProt,B2HK68,GenBank,ACC43565,,,M,MarP,,marP::Tn,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,membrane serine protease involved in acid tolerance,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27512905,PubMed,10.1016/j.chom.2016.07.007,Cell Host Microbe.2016 Aug 10;20(2):250-8,lr404@cam.ac.uk,"IFNg enhances macrophage killing through multiple mechanisms, and dead mycobacteria are trafficked to macrophage lysosomes independently of IFNg.larval hindbrain ventricle; larval caudal vein",S Levitte 2016,2016,3 genes,Levitte-2016-Mycobacterial Acid Tolerance Enab,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8764,PHI:6709,UniProt,B2HHN7,GenBank,ACC41735,,,M,ptpA,,ptpA::Tn,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,tyrosine phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27512905,PubMed,10.1016/j.chom.2016.07.007,Cell Host Microbe.2016 Aug 10;20(2):250-8,lr404@cam.ac.uk,"IFNg enhances macrophage killing through multiple mechanisms, and dead mycobacteria are trafficked to macrophage lysosomes independently of IFNg.larval hindbrain ventricle; larval caudal vein",S Levitte 2016,2016,3 genes,Levitte-2016-Mycobacterial Acid Tolerance Enab,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8765,PHI:6710,,no data found,,,,,,ESX-1,,,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,secretion system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27512905,PubMed,10.1016/j.chom.2016.07.007,Cell Host Microbe.2016 Aug 10;20(2):250-8,lr404@cam.ac.uk,"IFNg enhances macrophage killing through multiple mechanisms, and dead mycobacteria are trafficked to macrophage lysosomes independently of IFNg.larval hindbrain ventricle; larval caudal vein",S Levitte 2016,2016,3 genes,Levitte-2016-Mycobacterial Acid Tolerance Enab,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8766,PHI:6711,UniProt,G4MV25,GenBank,EHA55759,,,RKS2993,gel1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8767,PHI:6712,UniProt,G4ML85,GenBank,EHA56821,,,70-15,gel2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8768,PHI:6713,UniProt,G4MWC3,GenBank,EHA55883,,,70-15,gel3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,wild type,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8769,PHI:6714,UniProt,G4MLP9,GenBank,EHA56882,,,70-15,gel4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,wild type,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8770,PHI:6715,UniProt,G4NAB0,GenBank,EHA50455,,,70-15,gel5,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8771,PHI:6713,UniProt,G4MWC3,GenBank,EHA55883,,,70-15,gel3,,,,,,PHI:6714,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,wild type,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8772,PHI:6714,UniProt,G4MLP9,GenBank,EHA56882,,,70-15,gel4,,,,,,PHI:6713,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,wild type,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8773,PHI:6712,UniProt,G4ML85,GenBank,EHA56821,,,70-15,gel2,,,,,,PHI:6713,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8774,PHI:6713,UniProt,G4MWC3,GenBank,EHA55883,,,70-15,gel3,,,,,,PHI:6712,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8775,PHI:6711,UniProt,G4MV25,GenBank,EHA55759,,,RKS2993,gel1,,,,,,PHI:6713; PHI:6714,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8776,PHI:6713,UniProt,G4MWC3,GenBank,EHA55883,,,70-15,gel3,,,,,,PHI:6711; PHI:6714,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8777,PHI:6714,UniProt,G4MLP9,GenBank,EHA56882,,,70-15,gel4,,,,,,PHI:6711; PHI:6713,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8778,PHI:6712,UniProt,G4ML85,GenBank,EHA56821,,,70-15,gel2,,,,,,PHI:6713; PHI:6714,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8779,PHI:6713,UniProt,G4MWC3,GenBank,EHA55883,,,70-15,gel3,,,,,,PHI:6712; PHI:6714,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8780,PHI:6714,UniProt,G4MLP9,GenBank,EHA56882,,,70-15,gel4,,,,,,PHI:6712; PHI:6713,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8781,PHI:6715,UniProt,G4NAB0,GenBank,EHA50455,,,70-15,gel5,,,,,,PHI:6713; PHI:6714,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8782,PHI:6713,UniProt,G4MWC3,GenBank,EHA55883,,,70-15,gel3,,,,,,PHI:6714; PHI:6715,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8783,PHI:6714,UniProt,G4MLP9,GenBank,EHA56882,,,70-15,gel4,,,,,,PHI:6713; PHI:6715,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8784,PHI:6711,UniProt,G4MV25,GenBank,EHA55759,,,RKS2993,gel1,,,,,,PHI:6712; PHI:6715,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8785,PHI:6712,UniProt,G4ML85,GenBank,EHA56821,,,70-15,gel2,,,,,,PHI:6711; PHI:6715,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8786,PHI:6715,UniProt,G4NAB0,GenBank,EHA50455,,,70-15,gel5,,,,,,PHI:6711; PHI:6712,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8787,PHI:6713,UniProt,G4MWC3,GenBank,EHA55883,,,70-15,gel3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,wild type,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8788,PHI:6714,UniProt,G4MLP9,GenBank,EHA56882,,,70-15,gel4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,wild type,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8789,PHI:6713,UniProt,G4MWC3,GenBank,EHA55883,,,70-15,gel3,,,,,,PHI:6714,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,wild type,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8790,PHI:6714,UniProt,G4MLP9,GenBank,EHA56882,,,70-15,gel4,,,,,,PHI:6713,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,no,no,no,,wild type,,wild type,,no,Congo red; calcofluor white; SDS; sorbitol; glycerol; hydrogen peroxide; NaCl,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; glycerol: CHEBI:17754; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,27568483,PubMed,10.1111/cmi.12659,CellMicrobiol.2016 Aug 29,s.j.gurr@exeter.ac.uk,"Gel proteins are expressed during infection-related development and plant infection and a mutant defective in three Gel enzymes (Gel1, Gel2 and Gel3) does not cause rice blast disease.",M Samalova 2016,2016,5 genes,"Samalova-2016-The beta-1,3-glucanosyltransfera",BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8791,PHI:6716,UniProt,H1VKZ0,GenBank,CCF40893,,,IMI 349063,ChSte7,,,,,,,80884,Colletotrichum higginsianum,,IMI349061,anthracnose (Cruciferae),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,"encodes a 522-amino acid protein containing a serine/threonine protein kinases, catalytic domain",,,Ste11-Ste7-Fus3/Kss1 kinase pathway,loss of pathogenicity,,yes,yes,yes,,wild type,,reduced; aberrant,reduced,no,,,,,,,gene disruption; gene complementation,,,YVS,27563675,PubMed,10.1155/2016/7496569,Biomed Res Int.2016;2016:7496569,luzheng@mail.hzau.edu.cn,"ChSte7is involved in regulation ofvegetativegrowth, appressorial formation of C. higginsianum and postinvasivegrowthin host tissues.",Q Yuan 2016,2016,1 gene,Yuan-2016-ChSte7 Is Required for Vegetative Gr,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8792,PHI:6717,UniProt,Q5SC61,GenBank,AAT95334,,,,mapk1,,,,,,,5811,Toxoplasma gondii,507601,GT1,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,mitogen-activated protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27475900,PubMed,10.1016/j.micinf.2016.07.004,Microbes Infect.2016 Nov;18(11):696-700,liuquan1973@hotmail.com,MAPKs are associated with inflammasome activation in T. gondii-infected mice.,S Wang 2016,2016,2 genes,Wang-2016-Toxoplasma gondii mitogen-activated,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8793,PHI:6718,UniProt,S7WC30,GenBank,EPR64414,,,GT1,mapk2,,,,,,,5811,Toxoplasma gondii,507601,GT1,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,mitogen-activated protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27475900,PubMed,10.1016/j.micinf.2016.07.004,Microbes Infect.2016 Nov;18(11):696-700,liuquan1973@hotmail.com,MAPKs are associated with inflammasome activation in T. gondii-infected mice.,S Wang 2016,2016,2 genes,Wang-2016-Toxoplasma gondii mitogen-activated,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8794,PHI:6719,UniProt,I1RPD3,GenBank,CEF88526,,,PH-1,FgPLC1,chromosome 3,,,,,,5518,Fusarium graminearum,,SF01-3,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,phospholipid hydrolase,,,Gpmk1 and Mgv1 MAP kinase signaling pathways,reduced virulence,yes,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,Congo red; SDS; D-sorbitol; H2O2; NaCl; KCl,Congo red: CHEBI:34653; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene disruption; gene complementation,,,YVS,27777035,PubMed,10.1016/j.fgb.2016.10.004,Fungal Genet Biol.2016 Dec;97:1-9,liangyc@sdau.edu.cn,"Deletion of FgPLC1, but not the other five FgPLC genes (FgPLC2, FgPLC3, FgPLC4, FgPLC5, FgPLC6), affected hyphal growth and conidiation.",Q Zhu 2016,2016,1 gene,Zhu-2016-The phospholipase C (FgPLC1) is invol,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8795,PHI:6720,UniProt,A0A0H3N294,GenBank,CAZ56804,,,BM407,relA,,,,,,PHI:6721,1307,Streptococcus suis,,SC19,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),Kunming,,,blood; brain; lung,bifunctional protein with (p)ppGpp synthetase and hydrolase domains,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27524648,PubMed,10.1016/j.micres.2016.05.007,Microbiol Res.2016 Oct;191:1-11,rzhou@mail.hzau.edu.cn,"Disruption of relA and relQ led to decreased adhesive and invasive ability to HEp-2 cells, and increased sensitivity to the blood killing and phagocytosis.",J Zhu 2016,2016,2 genes,Zhu-2016-(p)ppGpp synthetases regulate the pat,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8796,PHI:6721,,no data found,,,,,,relQ,,,,,,PHI:6720,1307,Streptococcus suis,,SC19,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),Kunming,,,blood; brain; lung,(p)ppGpp synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,27524648,PubMed,10.1016/j.micres.2016.05.007,Microbiol Res.2016 Oct;191:1-11,rzhou@mail.hzau.edu.cn,"Disruption of relA and relQ led to decreased adhesive and invasive ability to HEp-2 cells, and increased sensitivity to the blood killing and phagocytosis.",J Zhu 2016,2016,2 genes,Zhu-2016-(p)ppGpp synthetases regulate the pat,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8797,PHI:6722,UniProt,Q8PGN7,GenBank,AAM38422,,,306,xanA,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,159033,Citrus x aurantiifolia (related: lime),,,,leaf,phosphoglucomutase,,,xanthan biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,27567706,PubMed,10.1016/j.bbapap.2016.08.014,Biochim Biophys Acta. 2016 Dec; 1864(12):1658-1666,seiji_l@hotmail.com,Phosphoglucomutase does not seem to be mandatory to the development of citrus canker symptoms but the impaired xanthan synthesis should affect citrus canker in some way.,L S Goto 2016,2016,1 gene,Goto-2016-Structural and functional characteri,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8798,PHI:6723,UniProt,Q8XNW2,GenBank,BAB79926,,,13,ChtD,,,,,,PHI:6724,1502,Clostridium perfringens,,JIR325,gas gangrene (human); clostridial myonecrosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,NEAT domain-containing cell surface protein involved in heme binding,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,27637108,PubMed,10.1371/journal.pone.0162981,PLoS One. 2016 Sep 16;11(9):e0162981,milena.awad@monash.edu,"Although the mutants were attenuated for virulence when tested in a mouse myonecrosis model, the virulence phenotype could not be restored via complementation and, secondary mutations were identified indicating that the chtD, chtE and srt genes of the cht locus do not appear to be essential for the growth and virulence of C. perfringens strain JIR325.",J M Choo 2016,2016,3 genes,Choo-2016-The NEAT Domain-Containing Proteins,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8799,PHI:6724,UniProt,Q8XNW1,GenBank,BAB79927,,,13,ChtE,,,,,,PHI:6723,1502,Clostridium perfringens,,JIR325,gas gangrene (human); clostridial myonecrosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,NEAT domain-containing cell surface protein involved in heme binding,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,27637108,PubMed,10.1371/journal.pone.0162981,PLoS One. 2016 Sep 16;11(9):e0162981,milena.awad@monash.edu,"Although the mutants were attenuated for virulence when tested in a mouse myonecrosis model, the virulence phenotype could not be restored via complementation and, secondary mutations were identified indicating that the chtD, chtE and srt genes of the cht locus do not appear to be essential for the growth and virulence of C. perfringens strain JIR325.",J M Choo 2016,2016,3 genes,Choo-2016-The NEAT Domain-Containing Proteins,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8800,PHI:6725,UniProt,Q8XNW0,GenBank,BAB79928,,,13,srt,,,,,,,1502,Clostridium perfringens,,JIR325,gas gangrene (human); clostridial myonecrosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,transpeptidase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,27637108,PubMed,10.1371/journal.pone.0162981,PLoS One. 2016 Sep 16;11(9):e0162981,milena.awad@monash.edu,"Although the mutants were attenuated for virulence when tested in a mouse myonecrosis model, the virulence phenotype could not be restored via complementation and, secondary mutations were identified indicating that the chtD, chtE and srt genes of the cht locus do not appear to be essential for the growth and virulence of C. perfringens strain JIR325.",J M Choo 2016,2016,3 genes,Choo-2016-The NEAT Domain-Containing Proteins,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8801,PHI:6726,UniProt,B2HMS5,GenBank,ACC43844,,,M,WhiB6,,,,,,,1781,Mycobacterium marinum,216594,M,granuloma,bony fishes,7955,Danio rerio (related: zebrafish),,,,,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27545883,PubMed,10.1016/j.celrep.2016.07.080,Cell Rep. 2016 Aug 30;16(9):2512-24,sychen@wh.iov.cn,WhiB6 differentially regulates the ESX-1 secretion system which is necessary for virulence and DosR dormancy regulons through its Fe-S cluster.,Z Chen 2016,2016,1 gene,Chen-2016-Mycobacterial WhiB6 Differentially R,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8802,PHI:6726,UniProt,B2HMS5,GenBank,ACC43844,,,M,WhiB6,,MB6-4CS,,,,,1781,Mycobacterium marinum,216594,M,granuloma,bony fishes,7955,Danio rerio (related: zebrafish),,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27545883,PubMed,10.1016/j.celrep.2016.07.080,Cell Rep. 2016 Aug 30;16(9):2512-24,sychen@wh.iov.cn,WhiB6 differentially regulates the ESX-1 secretion system which is necessary for virulence and DosR dormancy regulons through its Fe-S cluster.,Z Chen 2016,2016,1 gene,Chen-2016-Mycobacterial WhiB6 Differentially R,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8803,PHI:6727,UniProt,Q887C1,,,,,DC3000,hrcC,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,RPT2a (Subunit of 19S regulatory particle of 26S proteasome) (mutation),UniProt: Q9SZD4; GenBank: BAD18016,leaf,type III secretion system,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation,,,YVS,27613851,PubMed,10.1104/pp.16.00808,Plant Physiol. 2016 Nov;172(3):1941-1958. Epub 2016 Sep 9,suayib.ustun@slu.se,Pseudomonas syringae pv. tomato DC3000 (Pst) inhibits proteasome activity in a type III secretion-dependent manner. Non-pathogenic Pst hrcC mutant causes higher bacterial densities in proteasome mutants than wild-type Arabidopsis,S Üstün 2016,2016,2 genes,Ustun-2016-The Proteasome Acts as a Hub for Pl,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8804,PHI:6728,UniProt,Q887C1,,,,,DC3000,hrcC,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,RPN12a (Subunit of 19S regulatory particle of 26S proteasome) (mutation),UniProt: Q9SGW3; GenBank: AAP86673,leaf,type III secretion system,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation,,,YVS,27613851,PubMed,10.1104/pp.16.00808,Plant Physiol. 2016 Nov;172(3):1941-1958. Epub 2016 Sep 9,suayib.ustun@slu.se,Pseudomonas syringae pv. tomato DC3000 (Pst) inhibits proteasome activity in a type III secretion-dependent manner. Non-pathogenic Pst hrcC mutant causes higher bacterial densities in proteasome mutants than wild-type Arabidopsis,S Üstün 2016,2016,2 genes,Ustun-2016-The Proteasome Acts as a Hub for Pl,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8805,PHI:6729,UniProt,P11557,GenBank,CAA33253,,,K-12,damX,,,,,,,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,urinary bladder,cell division protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,27486187,PubMed,10.1128/mBio.00642-16,MBio. 2016 Aug 2;7(4). pii: e00642-16,jakobm@bmb.sdu.dk,A lack of reversible bacterial filamentation in a damX deletion mutant in vitro and absence of a filamentous response by this mutant in a murine model of cystitis was demonstrated.,S Khandige 2016,2016,1 gene,Khandige-2016-DamX Controls Reversible Cell Mo,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8806,PHI:6730,UniProt,K9FDB7,GenBank,EKV07229,,,PHI26,PdMpkB,,,,,,,36651,Penicillium digitatum,1170229,PHI26,green mold (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),,,,fruit,mitogen-activated protein kinase,,,Fus3/Kiss1 MAP kinase-mediated signaling pathway,reduced virulence,,,no,yes,,reduced,,reduced; aberrant,,no,D-sorbitol; NaCl; CaCl2; MgCl2,D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; CaCl2: CHEBI:3312; MgCl2: CHEBI:6636,,,,,gene disruption; gene complementation,,,YVS,27529663,PubMed,10.1016/j.ijfoodmicro.2016.08.001,Int J Food Microbiol. 2016 Nov 7;236:167-76,krchung@nchu.edu.tw,"Inactivation of PdMpkB impacted expression of the genes associated with cell wall-degrading enzyme activities, carbohydrate and amino acid metabolisms, conidial formation and numerous metabolic processes.",H Ma 2016,2016,1 gene,Ma-2016-The citrus postharvest pathogen Penici,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8807,PHI:6731,UniProt,P9WN43,GenBank,CCP43969,,,H37Rv,glgC,,,,,,PHI:6732,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,glucose-1-phosphate adenylyltransferase,,,alpha-glucan biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27513637,PubMed,10.1371/journal.ppat.1005768,PLoS Pathog.2016 Aug 11;12(8):e1005768,rainer.kalscheuer@uni-duesseldorf.de,"alpha-Glucan biosynthesis in mycobacteria is carried out by GlgC-GlgA, Rv3032 and TreS-Pep2-GlgE pathways.",H K Brandl 2016,2016,2 genes,Koliwer-Brandl-2016-Metabolic Network for the,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8808,PHI:6732,UniProt,P9WQ19,GenBank,CCP42851,,,H37Rv,treS,,,,,,PHI:6731,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,trehalose synthase,,,alpha-glucan biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27513637,PubMed,10.1371/journal.ppat.1005768,PLoS Pathog.2016 Aug 11;12(8):e1005768,rainer.kalscheuer@uni-duesseldorf.de,"alpha-Glucan biosynthesis in mycobacteria is carried out by GlgC-GlgA, Rv3032 and TreS-Pep2-GlgE pathways.",H K Brandl 2016,2016,2 genes,Koliwer-Brandl-2016-Metabolic Network for the,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8809,PHI:6732,UniProt,P9WQ19,GenBank,CCP42851,,,H37Rv,treS,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,trehalose synthase,,,alpha-glucan biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27513637,PubMed,10.1371/journal.ppat.1005768,PLoS Pathog.2016 Aug 11;12(8):e1005768,rainer.kalscheuer@uni-duesseldorf.de,"alpha-Glucan biosynthesis in mycobacteria is carried out by GlgC-GlgA, Rv3032 and TreS-Pep2-GlgE pathways.",H K Brandl 2016,2016,2 genes,Koliwer-Brandl-2016-Metabolic Network for the,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8810,PHI:6733,UniProt,P24216,GenBank,AAC74991,,,K-12,fliD,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,flagellar filament capping protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27655246,PubMed,10.1007/s00203-016-1291-8,Arch Microbiol.2016 Sep 21,rudi.vogel@wzw.tum.de,"Co-feeding enterohemorrhagic E. coli (EHEC) with Enterococcus faecalis Symbioflor®, a protective probiotic, significantly increased the worms' lifespan. Downregulation of several virulence-associated genes in the presence of Symbioflor®, including virulence key genes was observed.",K Neuhaus 2016,2016,5 genes,Neuhaus-2016-Probiotic Enterococcus faecalis S,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8811,PHI:6734,UniProt,Q8XC86,GenBank,AE005594_13,,,EDL933,espB,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,secreted protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27655246,PubMed,10.1007/s00203-016-1291-8,Arch Microbiol.2016 Sep 21,rudi.vogel@wzw.tum.de,"Co-feeding enterohemorrhagic E. coli (EHEC) with Enterococcus faecalis Symbioflor®, a protective probiotic, significantly increased the worms' lifespan. Downregulation of several virulence-associated genes in the presence of Symbioflor®, including virulence key genes was observed.",K Neuhaus 2016,2016,5 genes,Neuhaus-2016-Probiotic Enterococcus faecalis S,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8812,PHI:6735,UniProt,Q8X3Z4,GenBank,AE005423_4,,,EDL933,Z3136,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27655246,PubMed,10.1007/s00203-016-1291-8,Arch Microbiol.2016 Sep 21,rudi.vogel@wzw.tum.de,"Co-feeding enterohemorrhagic E. coli (EHEC) with Enterococcus faecalis Symbioflor®, a protective probiotic, significantly increased the worms' lifespan. Downregulation of several virulence-associated genes in the presence of Symbioflor®, including virulence key genes was observed.",K Neuhaus 2016,2016,5 genes,Neuhaus-2016-Probiotic Enterococcus faecalis S,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8813,PHI:6736,UniProt,Q8X415,GenBank,AE005492_1,,,EDL933,Z3917,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27655246,PubMed,10.1007/s00203-016-1291-8,Arch Microbiol.2016 Sep 21,rudi.vogel@wzw.tum.de,"Co-feeding enterohemorrhagic E. coli (EHEC) with Enterococcus faecalis Symbioflor®, a protective probiotic, significantly increased the worms' lifespan. Downregulation of several virulence-associated genes in the presence of Symbioflor®, including virulence key genes was observed.",K Neuhaus 2016,2016,5 genes,Neuhaus-2016-Probiotic Enterococcus faecalis S,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8814,PHI:6737,UniProt,O82887,GenBank,AAC70120,,,EDL933,L7052,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27655246,PubMed,10.1007/s00203-016-1291-8,Arch Microbiol.2016 Sep 21,rudi.vogel@wzw.tum.de,"Co-feeding enterohemorrhagic E. coli (EHEC) with Enterococcus faecalis Symbioflor®, a protective probiotic, significantly increased the worms' lifespan. Downregulation of several virulence-associated genes in the presence of Symbioflor®, including virulence key genes was observed.",K Neuhaus 2016,2016,5 genes,Neuhaus-2016-Probiotic Enterococcus faecalis S,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8815,PHI:6738,UniProt,O30916,GenBank,AIE04888,,,VNP20009,sopB,,SopB delta288-309,,,,,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,food poisoning; gastroenteritis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,intestinal epithelium,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,N-acetyl-L-cysteine,N-acetyl-L-cysteine: CHEBI:28939,,,,,gene mutation; gene complementation,,,YVS,27473656,PubMed,10.1016/j.bbrc.2016.07.116,Biochem Biophys Res Commun. 2016 Sep 16;478(2):618-23,ruanhaihua@tjcu.edu.cn,"By studying the response of Traf6+/+ and Traf6-/- mouse embryonic fibroblasts to S. typhimurium infection, it was found that TRAF6 promoted apoptosis by increasing ROS accumulation. SopB binds to TRAF6 and forms a trap preventing the mitochondrial recruitment of TRAF6.",H Ruan 2016,2016,1 gene,Ruan-2016-The Salmonella effector SopB prevent,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8816,PHI:6739,UniProt,G4ML12,GenBank,XP_003711051,,,70-15,MoGls2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,glycoside hydrolase,,,,reduced virulence,,yes,yes,yes,,increased,reduced,reduced,reduced,no,NaCl; KCl; sorbitol; CFW; CR; SDS,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:17924; CFW: CHEBI:50011; CR: CHEBI:34653; SDS: CHEBI:8984,,,,,gene disruption; gene complementation,,,YVS,27607237,PubMed,10.1371/journal.pone.0162243,PLoS One. 2016 Sep 8;11(9):e0162243,hfzhang@njau.edu.cn,MoGLS2 likely have a potential role in the infection process of the rice blast fungus.,M Li 2016,2016,1 gene,Li-2016-Glycoside Hydrolase MoGls2 Controls As,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8817,PHI:6739,UniProt,G4ML12,GenBank,XP_003711051,,,70-15,MoGls2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,glycoside hydrolase,,,,reduced virulence,,yes,yes,yes,,increased,reduced,reduced,reduced,no,NaCl; KCl; sorbitol; CFW; CR; SDS,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:17924; CFW: CHEBI:50011; CR: CHEBI:34653; SDS: CHEBI:8984,,,,,gene disruption; gene complementation,,,YVS,27607237,PubMed,10.1371/journal.pone.0162243,PLoS One. 2016 Sep 8;11(9):e0162243,hfzhang@njau.edu.cn,MoGLS2 likely have a potential role in the infection process of the rice blast fungus.,M Li 2016,2016,1 gene,Li-2016-Glycoside Hydrolase MoGls2 Controls As,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8818,PHI:6740,,no data found,,,,,,CPS (capsular polysaccharide),,none unaltered wild-type serotype III,,,,,1311,Streptococcus agalactiae,1319,group B strain 83-T-61,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,Siglec-9,UniProt: Q9Y336; GenBank: AAD26428,blood,sialic acid-binding Ig-like lectin 9,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,27544323,PubMed,10.1016/j.micpath.2016.08.014,Microb Pathog. 2016 Oct;99:106-110,msaito@med.uoeh-u.ac.jp,sSiglec-9 provides an antibacterial benefit against GBS serotype III infection in the transgenic mice mediated by interfering with the down-regulation of the immune responsiveness of neutrophils.,M Saito 2016,2016,1 gene,Saito-2016-A soluble form of Siglec-9 provides,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8819,PHI:6741,,no data found,GenBank,CXA39877,,,3135STDY5861208,marT,,,,,,,28901,Salmonella enterica,1443995,subsp. enterica serovar Typhi strain STH2370,salmonellosis,primates,9606,Homo sapiens (related: human),U-937 cell line,,,macrophage,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,27567490,PubMed,10.1016/j.meegid.2016.08.029,Infect Genet Evol.2016 Nov;45:111-121,all.ortega@uandresbello.edu,"marT pseudogenization in S.Typhi contributes to the surV-dependent survival to H2O2, and to the proliferation inside U937 cells.",A P Ortega 2016,2016,2 genes,Ortega-2016-Lose to win_ marT pseudogenization,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8820,PHI:6742,UniProt,Q8Z2I7,GenBank,AAO71250,,,Ty2,surV,,,,,,,28901,Salmonella enterica,1443995,subsp. enterica serovar Typhi strain STH2370,salmonellosis,primates,9606,Homo sapiens (related: human),U-937 cell line,,,macrophage,contributes to H2O2 resistance,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,27567490,PubMed,10.1016/j.meegid.2016.08.029,Infect Genet Evol.2016 Nov;45:111-121,all.ortega@uandresbello.edu,"marT pseudogenization in S.Typhi contributes to the surV-dependent survival to H2O2, and to the proliferation inside U937 cells.",A P Ortega 2016,2016,2 genes,Ortega-2016-Lose to win_ marT pseudogenization,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8821,PHI:6741,,no data found,GenBank,CXA39877,,,3135STDY5861208,marT,,,,,,,28901,Salmonella enterica,1443995,subsp. enterica serovar Typhi strain STH2370,salmonellosis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,27567490,PubMed,10.1016/j.meegid.2016.08.029,Infect Genet Evol.2016 Nov;45:111-121,all.ortega@uandresbello.edu,"marT pseudogenization in S.Typhi contributes to the surV-dependent survival to H2O2, and to the proliferation inside U937 cells.",A P Ortega 2016,2016,2 genes,Ortega-2016-Lose to win_ marT pseudogenization,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8822,PHI:6742,UniProt,Q8Z2I7,GenBank,AAO71250,,,Ty2,surV,,,,,,,28901,Salmonella enterica,1443995,subsp. enterica serovar Typhi strain STH2370,salmonellosis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,contributes to H2O2 resistance,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,27567490,PubMed,10.1016/j.meegid.2016.08.029,Infect Genet Evol.2016 Nov;45:111-121,all.ortega@uandresbello.edu,"marT pseudogenization in S.Typhi contributes to the surV-dependent survival to H2O2, and to the proliferation inside U937 cells.",A P Ortega 2016,2016,2 genes,Ortega-2016-Lose to win_ marT pseudogenization,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8823,PHI:6743,UniProt,Q7CR58,GenBank,AAL19233,,,LT2,Hcp1,,,,Tae4,UniProt: A0A0U1JRP7; GenBank: CNR22342,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,cecum; colon,T6SS subunit and a putative cytoplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27503894,PubMed,10.1073/pnas.1608858113,Proc Natl Acad Sci U S A.2016 Aug 23;113(34):E5044-51,dmonack@stanford.edu,K. oxytoca is killed in the host gut in an Hcp1-dependent manner and that the T6SS antibacterial activity is essential for Salmonella to establish infection within the host gut. These findings provide an example of pathogen T6SS-dependent killing of commensal bacteria as a mechanism to successfully colonize the host gut.,T G Sana 2016,2016,3 genes,Sana-2016-Salmonella Typhimurium utilizes a T6,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8824,PHI:6744,UniProt,Q93IS3,GenBank,AAL19236,,,LT2,Hcp2,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,cecum; colon,T6SS subunit and a putative cytoplasmic protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27503894,PubMed,10.1073/pnas.1608858113,Proc Natl Acad Sci U S A.2016 Aug 23;113(34):E5044-51,dmonack@stanford.edu,K. oxytoca is killed in the host gut in an Hcp1-dependent manner and that the T6SS antibacterial activity is essential for Salmonella to establish infection within the host gut. These findings provide an example of pathogen T6SS-dependent killing of commensal bacteria as a mechanism to successfully colonize the host gut.,T G Sana 2016,2016,3 genes,Sana-2016-Salmonella Typhimurium utilizes a T6,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8825,PHI:6745,UniProt,A0A0U1JRP7,GenBank,CNR22342,,,CH43,Tae4,,,,Hcp1,UniProt: Q7CR58; GenBank: AAL19233,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,cecum; colon,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27503894,PubMed,10.1073/pnas.1608858113,Proc Natl Acad Sci U S A.2016 Aug 23;113(34):E5044-51,dmonack@stanford.edu,K. oxytoca is killed in the host gut in an Hcp1-dependent manner and that the T6SS antibacterial activity is essential for Salmonella to establish infection within the host gut. These findings provide an example of pathogen T6SS-dependent killing of commensal bacteria as a mechanism to successfully colonize the host gut.,T G Sana 2016,2016,3 genes,Sana-2016-Salmonella Typhimurium utilizes a T6,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8826,PHI:6743,UniProt,Q7CR58,GenBank,AAL19233,,,LT2,Hcp1,,,,Tae4,UniProt: A0A0U1JRP7; GenBank: CNR22342,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,T6SS subunit and a putative cytoplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27503894,PubMed,10.1073/pnas.1608858113,Proc Natl Acad Sci U S A.2016 Aug 23;113(34):E5044-51,dmonack@stanford.edu,K. oxytoca is killed in the host gut in an Hcp1-dependent manner and that the T6SS antibacterial activity is essential for Salmonella to establish infection within the host gut. These findings provide an example of pathogen T6SS-dependent killing of commensal bacteria as a mechanism to successfully colonize the host gut.,T G Sana 2016,2016,3 genes,Sana-2016-Salmonella Typhimurium utilizes a T6,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8827,PHI:6744,UniProt,Q93IS3,GenBank,AAL19236,,,LT2,Hcp2,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,T6SS subunit and a putative cytoplasmic protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27503894,PubMed,10.1073/pnas.1608858113,Proc Natl Acad Sci U S A.2016 Aug 23;113(34):E5044-51,dmonack@stanford.edu,K. oxytoca is killed in the host gut in an Hcp1-dependent manner and that the T6SS antibacterial activity is essential for Salmonella to establish infection within the host gut. These findings provide an example of pathogen T6SS-dependent killing of commensal bacteria as a mechanism to successfully colonize the host gut.,T G Sana 2016,2016,3 genes,Sana-2016-Salmonella Typhimurium utilizes a T6,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8828,PHI:6745,UniProt,A0A0U1JRP7,GenBank,CNR22342,,,CH43,Tae4,,,,Hcp1,UniProt: Q7CR58; GenBank: AAL19233,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27503894,PubMed,10.1073/pnas.1608858113,Proc Natl Acad Sci U S A.2016 Aug 23;113(34):E5044-51,dmonack@stanford.edu,K. oxytoca is killed in the host gut in an Hcp1-dependent manner and that the T6SS antibacterial activity is essential for Salmonella to establish infection within the host gut. These findings provide an example of pathogen T6SS-dependent killing of commensal bacteria as a mechanism to successfully colonize the host gut.,T G Sana 2016,2016,3 genes,Sana-2016-Salmonella Typhimurium utilizes a T6,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8829,PHI:6746,UniProt,J5JMB3,GenBank,EJP64226,,,ARSEF 2860,Mdj1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,biogenesis of functional mitochondria,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,reduced,no,H2O2; Congo red; NaCl; menadione; carbendazim,"H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; menadione: CHEBI:28869; carbendazim: CHEBI:3392, CAS:10605-21-7",,,,,gene disruption; gene complementation,,,YVS,27514385,PubMed,10.1007/s00253-016-7757-4,Appl Microbiol Biotechnol. 2017 Jan;101(1):185-195,mgfeng@zju.edu.cn,"Compared to wild-type, the deletion mutant was significantly more sensitive to the stresses of cell wall perturbation, high osmolarity, oxidation, carbendazim fungicide, several metal ions, and acidic/alkaline pH during conidial germination and/or colony growth.",J Wang 2016,2016,1 gene,Wang-2016-Vital role for the J-domain protein,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8830,PHI:6747,UniProt,P54291,GenBank,AAC44037,,,PAO1,rhlI,chromosome 1,deltaRhlI::Tn501,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),LACA,,,kidney; bladder,acyl-homoserine-lactone synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27549211,PubMed,10.1007/s10482-016-0755-9,Antonie Van Leeuwenhoek. 2016 Dec;109(12):1535-1544,rkgupta08@gmail.com,The rhl QSS mutant strains showed significantly reduced pathogenicity.,R K Gupta 2016,2016,2 genes,Gupta-2016-Rhl quorum sensing affects the viru,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8831,PHI:6748,UniProt,P54292,GenBank,AAC44036,,,PAO1,rhlR,chromosome 1,deltaRhlR::Tn501,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),LACA,,,kidney; bladder,QSS regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27549211,PubMed,10.1007/s10482-016-0755-9,Antonie Van Leeuwenhoek. 2016 Dec;109(12):1535-1544,rkgupta08@gmail.com,The rhl QSS mutant strains showed significantly reduced pathogenicity.,R K Gupta 2016,2016,2 genes,Gupta-2016-Rhl quorum sensing affects the viru,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8832,PHI:6749,UniProt,Q55M11,GenBank,EAL18940,,,B-3501A,UGT1,chromosome 9,,,,,,5207,Cryptococcus neoformans,214684,JEC21,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,UDP-galactose/UDP-GalNAc transporter,,,,loss of pathogenicity,yes,,,,,,,reduced,,no,Congo red; SDS; D-sorbitol; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,YVS,27496760,PubMed,10.1093/glycob/cww078,Glycobiology. 2017 Jan;27(1):87-98,doering@wustl.edu,Deletion of UGT1 resulted in growth and mating defects along with altered capsule and cellular morphology.,L X Li 2016,2016,1 gene,Li-2016-Cryptococcus neoformans UGT1 encodes a,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8833,PHI:6750,UniProt,Q4WYT1,GenBank,EAL92172,,,Af293,Fbx15,chromosome 3,,,GlcA; SkpA,UniProt: Q4WJS6; GenBank: EAL88206; UniProt: Q4WTT8; GenBank: EAL91988,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,controls transcriptional repression and is a part of SCF E3 ubiquitin ligases,,,stress response pathways,loss of pathogenicity,,,,,,,,,,no,H2O2; menadione sodium bisulfite,H2O2: CHEBI:16240; menadione sodium bisulfite: CHEBI:63928,,,,,gene mutation; gene complementation,,,YVS,27649508,PubMed,10.1371/journal.ppat.1005899,PLoS Pathog. 2016 Sep 20;12(9):e1005899,gbraus@gwdg.de,"During non-stress conditions Fbx15 is phosphorylatedand F-box mediated interaction with SkpA preferentially happens in smaller subpopulations in the cytoplasm. Fbx15 is required for an appropriate oxidative stress response, which results in rapid dephosphorylation of Fbx15 and a shift of the cellular interaction with SkpA to the nucleus.",B Jöhnk 2016,2016,4 genes,Johnk-2016-SCF Ubiquitin Ligase F-box Protein,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8834,PHI:6751,UniProt,Q4WQ36,GenBank,EAL89648,,,Af293,Fbx23,chromosome 4,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,initiates asexual development,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,27649508,PubMed,10.1371/journal.ppat.1005899,PLoS Pathog. 2016 Sep 20;12(9):e1005899,gbraus@gwdg.de,"During non-stress conditions Fbx15 is phosphorylatedand F-box mediated interaction with SkpA preferentially happens in smaller subpopulations in the cytoplasm. Fbx15 is required for an appropriate oxidative stress response, which results in rapid dephosphorylation of Fbx15 and a shift of the cellular interaction with SkpA to the nucleus.",B Jöhnk 2016,2016,4 genes,Johnk-2016-SCF Ubiquitin Ligase F-box Protein,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8835,PHI:6752,UniProt,Q4WJH3,GenBank,EAL88309,,,Af293,GrrA,chromosome 1,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,required for maturation of sexual spores,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,27649508,PubMed,10.1371/journal.ppat.1005899,PLoS Pathog. 2016 Sep 20;12(9):e1005899,gbraus@gwdg.de,"During non-stress conditions Fbx15 is phosphorylatedand F-box mediated interaction with SkpA preferentially happens in smaller subpopulations in the cytoplasm. Fbx15 is required for an appropriate oxidative stress response, which results in rapid dephosphorylation of Fbx15 and a shift of the cellular interaction with SkpA to the nucleus.",B Jöhnk 2016,2016,4 genes,Johnk-2016-SCF Ubiquitin Ligase F-box Protein,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8836,PHI:6753,UniProt,Q4WJS6,GenBank,EAL88206,,,Af293,GlcA,chromosome 1,,,Fbx15,UniProt: Q4WYT1; GenBank: EAL92172,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,serine/threonine-protein phosphatase,,,,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,YVS,27649508,PubMed,10.1371/journal.ppat.1005899,PLoS Pathog. 2016 Sep 20;12(9):e1005899,gbraus@gwdg.de,"During non-stress conditions Fbx15 is phosphorylatedand F-box mediated interaction with SkpA preferentially happens in smaller subpopulations in the cytoplasm. Fbx15 is required for an appropriate oxidative stress response, which results in rapid dephosphorylation of Fbx15 and a shift of the cellular interaction with SkpA to the nucleus.",B Jöhnk 2016,2016,4 genes,Johnk-2016-SCF Ubiquitin Ligase F-box Protein,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8837,PHI:6754,,no data found,,,,,,bbf1,,mutant lacking bbf1-18,,,,PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,bbf31-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.,P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8838,PHI:6755,,no data found,,,,,,bbf2,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8839,PHI:6756,,no data found,,,,,,bbf3,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8840,PHI:6757,,no data found,,,,,,bbf4,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8841,PHI:6758,,no data found,,,,,,bbf5,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8842,PHI:6759,,no data found,,,,,,bbf6,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8843,PHI:6760,,no data found,,,,,,bbf7,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8844,PHI:6761,,no data found,,,,,,bbf8,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8845,PHI:6762,,no data found,,,,,,bbf9,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8846,PHI:6763,,no data found,,,,,,bbf10,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8847,PHI:6764,,no data found,,,,,,bbf11,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8848,PHI:6765,,no data found,,,,,,bbf12,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8849,PHI:6766,,no data found,,,,,,bbf13,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6767; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8850,PHI:6767,,no data found,,,,,,bbf14,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6768; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8851,PHI:6768,,no data found,,,,,,bbf15,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6769; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8852,PHI:6769,,no data found,,,,,,bbf16,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6770; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8853,PHI:6770,,no data found,,,,,,bbf17,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6771,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8854,PHI:6771,,no data found,,,,,,bbf18,,mutant lacking bbf1-18,,,,PHI:6754; PHI:6755; PHI:6756; PHI:6757; PHI:6758; PHI:6759; PHI:6760; PHI:6761; PHI:6762; PHI:6763; PHI:6764; PHI:6765; PHI:6766; PHI:6767; PHI:6768; PHI:6769; PHI:6770,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8855,PHI:6772,,no data found,,,,,,bbf19,,mutant lacking bbf19-22,,,,PHI:6773; PHI:6774; PHI:6775,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8856,PHI:6773,UniProt,O51025,GenBank,AAC66376,,,B31,bbf20,,mutant lacking bbf19-22,,,,PHI:6772; PHI:6774; PHI:6775,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8857,PHI:6774,,no data found,,,,,,bbf21,,mutant lacking bbf19-22,,,,PHI:6772; PHI:6773; PHI:6775,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8858,PHI:6775,,no data found,,,,,,bbf22,,mutant lacking bbf19-22,,,,PHI:6772; PHI:6773; PHI:6774,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8859,PHI:6776,,no data found,,,,,,bbf27,,mutant lacking bbf27-30,,,,PHI:6777; PHI:6778; PHI:6779,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8860,PHI:6777,,no data found,,,,,,bbf28,,mutant lacking bbf27-30,,,,PHI:6776; PHI:6778; PHI:6779,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8861,PHI:6778,,no data found,,,,,,bbf29,,mutant lacking bbf27-30,,,,PHI:6776; PHI:6777; PHI:6779,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8862,PHI:6779,,no data found,,,,,,bbf30,,mutant lacking bbf27-30,,,,PHI:6776; PHI:6777; PHI:6778,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood; heart; joint; bladder; ear,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27502325,PubMed,10.1186/s12866-016-0806-4.,BMC Microbiol.2016 Aug 8;16(1):180,tbankhead@vetmed.wsu.edu,"28kb linear plasmid, 1p28-1 with 32 ORF designated bbf01-bbf32 contains the VMP-like sequence (vls) locus responsible for antigenic variation of a vls-expressed (VlsE) lipoprotein.",P R H Magunda 2016,2016,26 genes,Magunda-2016-Investigating the potential role,BATCH_063C,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8863,PHI:6780,UniProt,G4NCS2,GenBank,EHA48315,,,70-15,MoCreC,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,catabolite repression protein,,,carbon catabolite repression pathway,reduced virulence,,yes,yes,,,reduced,,,,no,Congo red; SDS,Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene disruption; gene complementation,,,YVS,27909797,PubMed,10.1007/s00294-016-0668-1,Curr Genet.2016 Dec 1,gdlufafu@163.com,"Carbon catabolite repression was defective as the mutant was more sensitive to allyl alcohol in the presence of glucose, and 2-deoxyglucose was unable to fully repress utilization of secondary carbon sources.",K A O Matar 2016,2016,1 gene,Matar-2016-WD40-repeat protein MoCreC is essen,BATCH_064A,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8864,PHI:6780,UniProt,G4NCS2,GenBank,EHA48315,,,70-15,MoCreC,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,catabolite repression protein,,,carbon catabolite repression pathway,reduced virulence,,yes,yes,,,reduced,,,,no,Congo red; SDS,Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene disruption; gene complementation,,,YVS,27909797,PubMed,10.1007/s00294-016-0668-1,Curr Genet.2016 Dec 1,gdlufafu@163.com,"Carbon catabolite repression was defective as the mutant was more sensitive to allyl alcohol in the presence of glucose, and 2-deoxyglucose was unable to fully repress utilization of secondary carbon sources.",K A O Matar 2016,2016,1 gene,Matar-2016-WD40-repeat protein MoCreC is essen,BATCH_064A,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8865,PHI:6781,UniProt,Q8Y0E7,GenBank,CAD14799,,,GMI1000,efpR,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Super Marmande,,,xylem,catabolic repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27911943,PubMed,10.1371/journal.ppat.1006044,PLoS Pathog.2016 Dec 2;12(12):e1006044,alice.guidot@inra.fr,efpR loss of function enhances R. solanacearum swimming and twitching motility.,A Perrier 2016,2016,1 gene,Perrier-2016-Enhanced in planta Fitness throug,BATCH_064A,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8866,PHI:6782,UniProt,D0C624,GenBank,EEX04439,,,ATCC 19606,kdpE,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,potassium-dependent protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,27923956,PubMed,10.1093/infdis/jiw476,J Infect Dis.2016 Dec 15;214(12):2006-2013. Epub 2016 Oct 5,ahmed.s.attia@staff.cu.edu.eg,The deltakdpE mutant is deficient in growth in K+-limited conditions.,R Samir 2016,2016,1 gene,Samir-2016-Adaptation to Potassium-Limitation,BATCH_064A,2017-01-01,MC,,,,,,,,,,,,,
,,Record 8867,PHI:6783,UniProt,P0CY27,GenBank,CARP1_CANAL,,,,sap1,,,,,,,5476,Candida albicans,237561,SC5314,oral candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,10540295,PubMed,10.1046/j.1365-2958.1999.01590.x,Mol Microbiol. 1999 Oct;34(1):169-80,hube@botanik.uni-hamburg.de,"Sap1-3, but not Sap4-6, contribute to tissue damage.",M Schaller 1999,1999,6 genes,Schaller-1999-Secreted aspartic proteinase (Sa,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8868,PHI:6784,UniProt,P0DJ06,GenBank,AAM21050,,,CAI4,sap2,,,,,,,5476,Candida albicans,237561,SC5314,oral candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10540295,PubMed,10.1046/j.1365-2958.1999.01590.x,Mol Microbiol. 1999 Oct;34(1):169-80,hube@botanik.uni-hamburg.de,"Sap1-3, but not Sap4-6, contribute to tissue damage.",M Schaller 1999,1999,6 genes,Schaller-1999-Secreted aspartic proteinase (Sa,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8869,PHI:6785,UniProt,P0CY29,GenBank,CARP3_CANAL,,,,sap3,,,,,,,5476,Candida albicans,237561,SC5314,oral candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,10540295,PubMed,10.1046/j.1365-2958.1999.01590.x,Mol Microbiol. 1999 Oct;34(1):169-80,hube@botanik.uni-hamburg.de,"Sap1-3, but not Sap4-6, contribute to tissue damage.",M Schaller 1999,1999,6 genes,Schaller-1999-Secreted aspartic proteinase (Sa,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8870,PHI:6783,UniProt,P0CY27,GenBank,CARP1_CANAL,,,,sap1,,,,,,PHI:6785,5476,Candida albicans,237561,SC5314,oral candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,10540295,PubMed,10.1046/j.1365-2958.1999.01590.x,Mol Microbiol. 1999 Oct;34(1):169-80,hube@botanik.uni-hamburg.de,"Sap1-3, but not Sap4-6, contribute to tissue damage.",M Schaller 1999,1999,6 genes,Schaller-1999-Secreted aspartic proteinase (Sa,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8871,PHI:6785,UniProt,P0CY29,GenBank,CARP3_CANAL,,,,sap3,,,,,,PHI:6783,5476,Candida albicans,237561,SC5314,oral candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,10540295,PubMed,10.1046/j.1365-2958.1999.01590.x,Mol Microbiol. 1999 Oct;34(1):169-80,hube@botanik.uni-hamburg.de,"Sap1-3, but not Sap4-6, contribute to tissue damage.",M Schaller 1999,1999,6 genes,Schaller-1999-Secreted aspartic proteinase (Sa,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8872,PHI:6786,UniProt,Q5A8N2,GenBank,CARP4_CANAL,,,,sap4,,,,,,PHI:6787; PHI:6788,5476,Candida albicans,237561,SC5314,oral candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10540295,PubMed,10.1046/j.1365-2958.1999.01590.x,Mol Microbiol. 1999 Oct;34(1):169-80,hube@botanik.uni-hamburg.de,"Sap1-3, but not Sap4-6, contribute to tissue damage.",M Schaller 1999,1999,6 genes,Schaller-1999-Secreted aspartic proteinase (Sa,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8873,PHI:6787,UniProt,P43094,GenBank,CAA82923,,,Ca74,sap5,,,,,,PHI:6786; PHI:6788,5476,Candida albicans,237561,SC5314,oral candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10540295,PubMed,10.1046/j.1365-2958.1999.01590.x,Mol Microbiol. 1999 Oct;34(1):169-80,hube@botanik.uni-hamburg.de,"Sap1-3, but not Sap4-6, contribute to tissue damage.",M Schaller 1999,1999,6 genes,Schaller-1999-Secreted aspartic proteinase (Sa,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8874,PHI:6788,UniProt,Q5AC08,GenBank,CARP6_CANAL,,,,sap6,,,,,,PHI:6786; PHI:6787,5476,Candida albicans,237561,SC5314,oral candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10540295,PubMed,10.1046/j.1365-2958.1999.01590.x,Mol Microbiol. 1999 Oct;34(1):169-80,hube@botanik.uni-hamburg.de,"Sap1-3, but not Sap4-6, contribute to tissue damage.",M Schaller 1999,1999,6 genes,Schaller-1999-Secreted aspartic proteinase (Sa,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8875,PHI:6789,UniProt,P0CY27,GenBank,CARP1_CANAL,,,,sap1,,,,,,,5476,Candida albicans,237561,SC5314,vaginal candidiasis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,vagina,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9841840,PubMed,10.1086/314546,J Infect Dis. 1999 Jan;179(1):201-8,cassone@iss.it,Null sap1 to sap3 but not sap4 to sap6 mutants lost most of the virulence of their parental strain SC5314.,F De Bernardis 1999,1999,6 genes,De Bernardis-1999-Evidence that members of the,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8876,PHI:6790,UniProt,P0DJ06,GenBank,AAM21050,,,CAI4,sap2,,,,,,,5476,Candida albicans,237561,SC5314,vaginal candidiasis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,vagina,secreted aspartic peptidase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,9841840,PubMed,10.1086/314546,J Infect Dis. 1999 Jan;179(1):201-8,cassone@iss.it,Null sap1 to sap3 but not sap4 to sap6 mutants lost most of the virulence of their parental strain SC5314.,F De Bernardis 1999,1999,6 genes,De Bernardis-1999-Evidence that members of the,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8877,PHI:6791,UniProt,P0CY29,GenBank,CARP3_CANAL,,,,sap3,,,,,,,5476,Candida albicans,237561,SC5314,vaginal candidiasis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,vagina,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9841840,PubMed,10.1086/314546,J Infect Dis. 1999 Jan;179(1):201-8,cassone@iss.it,Null sap1 to sap3 but not sap4 to sap6 mutants lost most of the virulence of their parental strain SC5314.,F De Bernardis 1999,1999,6 genes,De Bernardis-1999-Evidence that members of the,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8878,PHI:6792,UniProt,Q5A8N2,GenBank,CARP4_CANAL,,,,sap4,,,,,,,5476,Candida albicans,237561,SC5314,vaginal candidiasis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,vagina,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9841840,PubMed,10.1086/314546,J Infect Dis. 1999 Jan;179(1):201-8,cassone@iss.it,Null sap1 to sap3 but not sap4 to sap6 mutants lost most of the virulence of their parental strain SC5314.,F De Bernardis 1999,1999,6 genes,De Bernardis-1999-Evidence that members of the,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8879,PHI:6793,UniProt,P43094,GenBank,CAA82923,,,Ca74,sap5,,,,,,,5476,Candida albicans,237561,SC5314,vaginal candidiasis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,vagina,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9841840,PubMed,10.1086/314546,J Infect Dis. 1999 Jan;179(1):201-8,cassone@iss.it,Null sap1 to sap3 but not sap4 to sap6 mutants lost most of the virulence of their parental strain SC5314.,F De Bernardis 1999,1999,6 genes,De Bernardis-1999-Evidence that members of the,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8880,PHI:6794,UniProt,Q5AC08,GenBank,CARP6_CANAL,,,,sap6,,,,,,,5476,Candida albicans,237561,SC5314,vaginal candidiasis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,vagina,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9841840,PubMed,10.1086/314546,J Infect Dis. 1999 Jan;179(1):201-8,cassone@iss.it,Null sap1 to sap3 but not sap4 to sap6 mutants lost most of the virulence of their parental strain SC5314.,F De Bernardis 1999,1999,6 genes,De Bernardis-1999-Evidence that members of the,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8881,PHI:6792,UniProt,Q5A8N2,GenBank,CARP4_CANAL,,,,sap4,,,,,,PHI:6793; PHI:6794,5476,Candida albicans,237561,SC5314,vaginal candidiasis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,vagina,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9841840,PubMed,10.1086/314546,J Infect Dis. 1999 Jan;179(1):201-8,cassone@iss.it,Null sap1 to sap3 but not sap4 to sap6 mutants lost most of the virulence of their parental strain SC5314.,F De Bernardis 1999,1999,6 genes,De Bernardis-1999-Evidence that members of the,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8882,PHI:6793,UniProt,P43094,GenBank,CAA82923,,,Ca74,sap5,,,,,,PHI:6792; PHI:6794,5476,Candida albicans,237561,SC5314,vaginal candidiasis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,vagina,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9841840,PubMed,10.1086/314546,J Infect Dis. 1999 Jan;179(1):201-8,cassone@iss.it,Null sap1 to sap3 but not sap4 to sap6 mutants lost most of the virulence of their parental strain SC5314.,F De Bernardis 1999,1999,6 genes,De Bernardis-1999-Evidence that members of the,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8883,PHI:6794,UniProt,Q5AC08,GenBank,CARP6_CANAL,,,,sap6,,,,,,PHI:6792; PHI:6793,5476,Candida albicans,237561,SC5314,vaginal candidiasis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,vagina,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9841840,PubMed,10.1086/314546,J Infect Dis. 1999 Jan;179(1):201-8,cassone@iss.it,Null sap1 to sap3 but not sap4 to sap6 mutants lost most of the virulence of their parental strain SC5314.,F De Bernardis 1999,1999,6 genes,De Bernardis-1999-Evidence that members of the,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8884,PHI:6795,UniProt,Q5ANA8,GenBank,MCA1_CANAL,,,,CaMCA1,,C292A,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,metacaspase-1,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,27815149,PubMed,10.1016/j.fgb.2016.10.007,Fungal Genet Biol. 2016 Dec;97:18-23,jmkim@cnu.ac.kr,"Edc3 is a key regulator of CaMca1 expression and both play essential roles in the oxidative stress-induced apoptosis and virulence. Filamentation defects were observed in the Camca1/Camca1 mutant cells, whereas this defect was only partial in CaMCA1C292A mutant cells.",J H Jeong 2016,2016,2 genes,Jeong-2016-Mutational analysis of metacaspase,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8885,PHI:6795,UniProt,Q5ANA8,GenBank,MCA1_CANAL,,,,CaMCA1,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,metacaspase-1,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,27815149,PubMed,10.1016/j.fgb.2016.10.007,Fungal Genet Biol. 2016 Dec;97:18-23,jmkim@cnu.ac.kr,"Edc3 is a key regulator of CaMca1 expression and both play essential roles in the oxidative stress-induced apoptosis and virulence. Filamentation defects were observed in the Camca1/Camca1 mutant cells, whereas this defect was only partial in CaMCA1C292A mutant cells.",J H Jeong 2016,2016,2 genes,Jeong-2016-Mutational analysis of metacaspase,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8886,PHI:6796,UniProt,A0A1D8PM93,GenBank,AOW29258,,,SC5314,Edc3,chromosome 4,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,mRNA decapping activator and a scaffold protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,27815149,PubMed,10.1016/j.fgb.2016.10.007,Fungal Genet Biol. 2016 Dec;97:18-23,jmkim@cnu.ac.kr,"Edc3 is a key regulator of CaMca1 expression and both play essential roles in the oxidative stress-induced apoptosis and virulence. Filamentation defects were observed in the Camca1/Camca1 mutant cells, whereas this defect was only partial in CaMCA1C292A mutant cells.",J H Jeong 2016,2016,2 genes,Jeong-2016-Mutational analysis of metacaspase,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8887,PHI:6797,UniProt,Q00909,GenBank,AAB72033,,,w-8,Tri5,,,,,,,5518,Fusarium graminearum,449239,GZ3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Wheaton,,,seedling,trichodiene synthase,,,trichothecene biosynthetic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,9274012,PubMed,10.1099/00221287-143-8-2583,Microbiology.1997 Aug;143 ( Pt 8):2583-91,proctorh@mail.ncaur.usda.gov,Trichothecenes contribute to the virulence of plant-pathogenic fungi.,R H Proctor 1997,1997,1 gene,9274012_Proctor1997,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8888,PHI:6798,UniProt,A0A0F6B5U6,GenBank,ACY89891,,,14028S,sptP,,,,SicP,UniProt: P0CL16; GenBank: AAL21759,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,27920299,PubMed,10.1128/JB.00647-16,J Bacteriol. 2017 Jan 30;199(4). pii: e00647-16,g.frankel@imperial.ac.uk,"Deletion of sptP from S. Typhi Ty2 did not affect invasion efficiency into HeLa cells and did not affect cytoskeletal recovery post-infection, whereas, deletion of sptP from S. Typhimurium resulted in significant phenotypic differences, including increased invasion and a failure to recover the host cytoskeleton post-infection.",R Johnson 2016,2016,3 genes,Johnson-2016-The type III secretion system eff,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8889,PHI:6798,UniProt,P74851,GenBank,AAO70341,,,Ty2,sptP,,,,SicP,UniProt: P0CL16; GenBank: AAL21759,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,27920299,PubMed,10.1128/JB.00647-16,J Bacteriol. 2017 Jan 30;199(4). pii: e00647-16,g.frankel@imperial.ac.uk,"Deletion of sptP from S. Typhi Ty2 did not affect invasion efficiency into HeLa cells and did not affect cytoskeletal recovery post-infection, whereas, deletion of sptP from S. Typhimurium resulted in significant phenotypic differences, including increased invasion and a failure to recover the host cytoskeleton post-infection.",R Johnson 2016,2016,3 genes,Johnson-2016-The type III secretion system eff,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8890,PHI:6799,UniProt,Q9RPM6,GenBank,AAD54239,,,X3744,SopE,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,YVS,27920299,PubMed,10.1128/JB.00647-16,J Bacteriol. 2017 Jan 30;199(4). pii: e00647-16,g.frankel@imperial.ac.uk,"Deletion of sptP from S. Typhi Ty2 did not affect invasion efficiency into HeLa cells and did not affect cytoskeletal recovery post-infection, whereas, deletion of sptP from S. Typhimurium resulted in significant phenotypic differences, including increased invasion and a failure to recover the host cytoskeleton post-infection.",R Johnson 2016,2016,3 genes,Johnson-2016-The type III secretion system eff,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8891,PHI:6799,UniProt,O52623,GenBank,AAC02071,,,SL1344,SopE,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,YVS,27920299,PubMed,10.1128/JB.00647-16,J Bacteriol. 2017 Jan 30;199(4). pii: e00647-16,g.frankel@imperial.ac.uk,"Deletion of sptP from S. Typhi Ty2 did not affect invasion efficiency into HeLa cells and did not affect cytoskeletal recovery post-infection, whereas, deletion of sptP from S. Typhimurium resulted in significant phenotypic differences, including increased invasion and a failure to recover the host cytoskeleton post-infection.",R Johnson 2016,2016,3 genes,Johnson-2016-The type III secretion system eff,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8892,PHI:6799,UniProt,O52623,GenBank,AAC02071,,,SL1344,SopE,,,,,,PHI:6800,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,YVS,27920299,PubMed,10.1128/JB.00647-16,J Bacteriol. 2017 Jan 30;199(4). pii: e00647-16,g.frankel@imperial.ac.uk,"Deletion of sptP from S. Typhi Ty2 did not affect invasion efficiency into HeLa cells and did not affect cytoskeletal recovery post-infection, whereas, deletion of sptP from S. Typhimurium resulted in significant phenotypic differences, including increased invasion and a failure to recover the host cytoskeleton post-infection.",R Johnson 2016,2016,3 genes,Johnson-2016-The type III secretion system eff,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8893,PHI:6800,UniProt,Q7CQD4,GenBank,AF217274_1,,,SL1345,SopE2,,,,,,PHI:6799,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene disruption,,,YVS,27920299,PubMed,10.1128/JB.00647-16,J Bacteriol. 2017 Jan 30;199(4). pii: e00647-16,g.frankel@imperial.ac.uk,"Deletion of sptP from S. Typhi Ty2 did not affect invasion efficiency into HeLa cells and did not affect cytoskeletal recovery post-infection, whereas, deletion of sptP from S. Typhimurium resulted in significant phenotypic differences, including increased invasion and a failure to recover the host cytoskeleton post-infection.",R Johnson 2016,2016,3 genes,Johnson-2016-The type III secretion system eff,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8894,PHI:6801,UniProt,A0A1D8PTM1,GenBank,AOW31479,,,SC5314,efg1,chromosome R,,,,,PHI:6802,5476,Candida albicans,237561,SC5314,disseminated candidiasis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,tongue,enhanced filamentous growth protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10377153,PubMed,no data found,Infect Immun.1999 Jul;67(7):3649-52,ckumamot@opal.tufts.edu,Deletion of EFG1 and CPH1 resulted in a mutant strain with reduced virulence but the loss of these two transcription factors was not sufficient to eliminate filamentous growth during infection or the development of invasive lesions in the tongue of immunosuppressed gnotobiotic piglets demonstrating that an Efg1p and Cph1p-independent pathway for promotion of filamentous growth exists.,P J Riggle 1999,1999,2 genes,Riggle-1999-Invasive lesions containing filame,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8895,PHI:6802,UniProt,P43079,GenBank,AAA64692,,,,cph1,chromosome 3,,,,,PHI:6801,5476,Candida albicans,237561,SC5314,disseminated candidiasis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,tongue,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10377153,PubMed,no data found,Infect Immun.1999 Jul;67(7):3649-52,ckumamot@opal.tufts.edu,Deletion of EFG1 and CPH1 resulted in a mutant strain with reduced virulence but the loss of these two transcription factors was not sufficient to eliminate filamentous growth during infection or the development of invasive lesions in the tongue of immunosuppressed gnotobiotic piglets demonstrating that an Efg1p and Cph1p-independent pathway for promotion of filamentous growth exists.,P J Riggle 1999,1999,2 genes,Riggle-1999-Invasive lesions containing filame,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8896,PHI:6803,UniProt,A0A1D8PET2,GenBank,AOW26651,,,SC5314,cla4,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,endothelial cell,serine/threonine protein kinase,,,filamentation regulatory pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10816502,PubMed,10.1128/IAI.68.6.3485-3490.2000,Infect Immun. 2000 Jun;68(6):3485-90,sfiller@ucla.edu,Efg1p and Tup1p contribute to virulence by regulating hyphal formation and the factors that enable C. albicans to invade and injure endothelial cells.,Q T Phan 2000,2000,4 genes,Phan-2000-Role of hyphal formation in interact,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8897,PHI:6804,UniProt,P43079,GenBank,AAA64692,,,,cph1,chromosome 3,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,endothelial cell,transcription factor,,,filamentation regulatory pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10816502,PubMed,10.1128/IAI.68.6.3485-3490.2000,Infect Immun. 2000 Jun;68(6):3485-90,sfiller@ucla.edu,Efg1p and Tup1p contribute to virulence by regulating hyphal formation and the factors that enable C. albicans to invade and injure endothelial cells.,Q T Phan 2000,2000,4 genes,Phan-2000-Role of hyphal formation in interact,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8898,PHI:6805,UniProt,A0A1D8PTM1,GenBank,AOW31479,,,SC5314,efg1,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,endothelial cell,enhanced filamentous growth protein,,,filamentation regulatory pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10816502,PubMed,10.1128/IAI.68.6.3485-3490.2000,Infect Immun. 2000 Jun;68(6):3485-90,sfiller@ucla.edu,Efg1p and Tup1p contribute to virulence by regulating hyphal formation and the factors that enable C. albicans to invade and injure endothelial cells.,Q T Phan 2000,2000,4 genes,Phan-2000-Role of hyphal formation in interact,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8899,PHI:6806,UniProt,C4YFX2,GenBank,AAB63195,,,W-01,tup1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,endothelial cell,transcriptional repressor,,,filamentation regulatory pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10816502,PubMed,10.1128/IAI.68.6.3485-3490.2000,Infect Immun. 2000 Jun;68(6):3485-90,sfiller@ucla.edu,Efg1p and Tup1p contribute to virulence by regulating hyphal formation and the factors that enable C. albicans to invade and injure endothelial cells.,Q T Phan 2000,2000,4 genes,Phan-2000-Role of hyphal formation in interact,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8900,PHI:6804,UniProt,P43079,GenBank,AAA64692,,,,cph1,chromosome 3,,,,,PHI:6805,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,endothelial cell,transcription factor,,,filamentation regulatory pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10816502,PubMed,10.1128/IAI.68.6.3485-3490.2000,Infect Immun. 2000 Jun;68(6):3485-90,sfiller@ucla.edu,Efg1p and Tup1p contribute to virulence by regulating hyphal formation and the factors that enable C. albicans to invade and injure endothelial cells.,Q T Phan 2000,2000,4 genes,Phan-2000-Role of hyphal formation in interact,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8901,PHI:6805,UniProt,A0A1D8PTM1,GenBank,AOW31479,,,SC5314,efg1,chromosome R,,,,,PHI:6804,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,endothelial cell,enhanced filamentous growth protein,,,filamentation regulatory pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10816502,PubMed,10.1128/IAI.68.6.3485-3490.2000,Infect Immun. 2000 Jun;68(6):3485-90,sfiller@ucla.edu,Efg1p and Tup1p contribute to virulence by regulating hyphal formation and the factors that enable C. albicans to invade and injure endothelial cells.,Q T Phan 2000,2000,4 genes,Phan-2000-Role of hyphal formation in interact,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8902,PHI:6807,UniProt,Q5A8N2,GenBank,CARP4_CANAL,,,,sap4,,,,,,PHI:6808; PHI:6809,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,peritoneal macrophage,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9632257,PubMed,10.1046/j.1365-2958.1998.00815.x,Mol Microbiol.1998 May;28(3):543-54,Michel.Monod@chuv.hospvd.ch,"deltasap4,5,6null mutant was killed 53% more effectively after contact with macrophages than the wild-type strain.",M B Zepelin 1998,1998,3 genes,Borg-von Zepeli-1998-The expression of the sec,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8903,PHI:6808,UniProt,P43094,GenBank,CAA82923,,,Ca74,sap5,,,,,,PHI:6807; PHI:6809,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,peritoneal macrophage,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9632257,PubMed,10.1046/j.1365-2958.1998.00815.x,Mol Microbiol.1998 May;28(3):543-54,Michel.Monod@chuv.hospvd.ch,"deltasap4,5,6null mutant was killed 53% more effectively after contact with macrophages than the wild-type strain.",M B Zepelin 1998,1998,3 genes,Borg-von Zepeli-1998-The expression of the sec,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8904,PHI:6809,UniProt,Q5AC08,GenBank,CARP6_CANAL,,,,sap6,,,,,,PHI:6807; PHI:6808,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,peritoneal macrophage,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,9632257,PubMed,10.1046/j.1365-2958.1998.00815.x,Mol Microbiol.1998 May;28(3):543-54,Michel.Monod@chuv.hospvd.ch,"deltasap4,5,6null mutant was killed 53% more effectively after contact with macrophages than the wild-type strain.",M B Zepelin 1998,1998,3 genes,Borg-von Zepeli-1998-The expression of the sec,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8905,PHI:6810,UniProt,O74205,GenBank,AAD13811,,,SB111,TOXE,,,,,,,5017,Bipolaris zeicola,,SB111,leaf spot (maize),monocots,4577,Zea mays (related: maize),,,,leaf,transcription factor,,,cyclic peptide biosynthesis,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,9894916,PubMed,10.1007/PL00008632,Mol Gen Genet.1998 Dec;260(5):462-9,walton@pilot.msu.edu,Mutation of TOXE by targeted gene disruption has no effect on growth and sporulation but abolishes HC-toxin production and pathogenicity. pathogen formerly called Cochliobolus carbonum teleomorph name,J H Ahn 1998,1998,1 gene,9894916_Ahn1998,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8906,PHI:6811,UniProt,P0CY27,GenBank,CARP1_CANAL,,,,sap1,,,,,,,5476,Candida albicans,237561,SC5314,peritonitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; pancreas; peritoneal cavity,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10569785,PubMed,no data found,Infect Immun.1999 Dec;67(12):6637-42,thomas.nichterlein@imh.ma.uni-heidelberg.de,"In contrast to the deltasap1, deltasap2 and deltasap3 mutants, only deltasap4-6 triple mutant induced a significantly reduced activity of ALT in comparison to the reference strain.",M KRETSCHMAR 1999,1999,6 genes,Kretschmar-1999-Germ tubes and proteinase acti,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8907,PHI:6812,UniProt,P0DJ06,GenBank,AAM21050,,,CAI4,sap2,,,,,,,5476,Candida albicans,237561,SC5314,peritonitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; pancreas; peritoneal cavity,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10569785,PubMed,no data found,Infect Immun.1999 Dec;67(12):6637-42,thomas.nichterlein@imh.ma.uni-heidelberg.de,"In contrast to the deltasap1, deltasap2 and deltasap3 mutants, only deltasap4-6 triple mutant induced a significantly reduced activity of ALT in comparison to the reference strain.",M KRETSCHMAR 1999,1999,6 genes,Kretschmar-1999-Germ tubes and proteinase acti,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8908,PHI:6813,UniProt,P0CY29,GenBank,CARP3_CANAL,,,,sap3,,,,,,,5476,Candida albicans,237561,SC5314,peritonitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; pancreas; peritoneal cavity,secreted aspartic peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10569785,PubMed,no data found,Infect Immun.1999 Dec;67(12):6637-42,thomas.nichterlein@imh.ma.uni-heidelberg.de,"In contrast to the deltasap1, deltasap2 and deltasap3 mutants, only deltasap4-6 triple mutant induced a significantly reduced activity of ALT in comparison to the reference strain.",M KRETSCHMAR 1999,1999,6 genes,Kretschmar-1999-Germ tubes and proteinase acti,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8909,PHI:6814,UniProt,Q5A8N2,GenBank,CARP4_CANAL,,,,sap4,,,,,,PHI:6815; PHI:6816,5476,Candida albicans,237561,SC5314,peritonitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; pancreas; peritoneal cavity,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10569785,PubMed,no data found,Infect Immun.1999 Dec;67(12):6637-42,thomas.nichterlein@imh.ma.uni-heidelberg.de,"In contrast to the deltasap1, deltasap2 and deltasap3 mutants, only deltasap4-6 triple mutant induced a significantly reduced activity of ALT in comparison to the reference strain.",M KRETSCHMAR 1999,1999,6 genes,Kretschmar-1999-Germ tubes and proteinase acti,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8910,PHI:6815,UniProt,P43094,GenBank,CAA82923,,,Ca74,sap5,,,,,,PHI:6814; PHI:6816,5476,Candida albicans,237561,SC5314,peritonitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; pancreas; peritoneal cavity,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10569785,PubMed,no data found,Infect Immun.1999 Dec;67(12):6637-42,thomas.nichterlein@imh.ma.uni-heidelberg.de,"In contrast to the deltasap1, deltasap2 and deltasap3 mutants, only deltasap4-6 triple mutant induced a significantly reduced activity of ALT in comparison to the reference strain.",M KRETSCHMAR 1999,1999,6 genes,Kretschmar-1999-Germ tubes and proteinase acti,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8911,PHI:6816,UniProt,Q5AC08,GenBank,CARP6_CANAL,,,,sap6,,,,,,PHI:6814; PHI:6815,5476,Candida albicans,237561,SC5314,peritonitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; pancreas; peritoneal cavity,secreted aspartic peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,10569785,PubMed,no data found,Infect Immun.1999 Dec;67(12):6637-42,thomas.nichterlein@imh.ma.uni-heidelberg.de,"In contrast to the deltasap1, deltasap2 and deltasap3 mutants, only deltasap4-6 triple mutant induced a significantly reduced activity of ALT in comparison to the reference strain.",M KRETSCHMAR 1999,1999,6 genes,Kretschmar-1999-Germ tubes and proteinase acti,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8912,PHI:6817,UniProt,O13328,GenBank,AAB66482,,,70-15,mac1,,deltamac1 sum1-99,,,,PHI:6818,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,adenylate cyclase,,,PMK1 MAPK pathway,reduced virulence,,no,,,,,,,,no,,,,,,,gene mutation,,,YVS,11006342,PubMed,10.1105/tpc.12.9.1703,Plant Cell.2000 Sep;12(9):1703-18,N.J.Talbot@exeter.ac.uk,"The regulatory PKA subunit mutant deltamac1 sum1-99 was originally isolated as a bypass suppressor of deltamac1 that restored its ability to make appressoria, however, the pathogenicity of Dmac1 sum1-99 mutants was not restored completely.",E Thines 2000,2000,2 genes,Thines-2000-MAP kinase and protein kinase A-de,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8913,PHI:6818,UniProt,O14448,GenBank,AAC34140,,,Guy11,sum1,,deltamac1 sum1-99,,,,PHI:6817,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cAMP-dependent protein kinase regulatory subunit,,,PMK1 MAPK pathway,reduced virulence,,no,,,,,,,,no,,,,,,,gene mutation,,,YVS,11006342,PubMed,10.1105/tpc.12.9.1703,Plant Cell.2000 Sep;12(9):1703-18,N.J.Talbot@exeter.ac.uk,"The regulatory PKA subunit mutant deltamac1 sum1-99 was originally isolated as a bypass suppressor of deltamac1 that restored its ability to make appressoria, however, the pathogenicity of Dmac1 sum1-99 mutants was not restored completely.",E Thines 2000,2000,2 genes,Thines-2000-MAP kinase and protein kinase A-de,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8914,PHI:6819,UniProt,Q9I238,GenBank,AE004635_3,,,PAO1,PA2077,,,,,,PHI:6820,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),Oregon R,,,,diol synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27929111,PubMed,10.1038/ncomms13823,Nat Commun.2016 Dec 8;7:13823,jcampos-gomez@southernresearch.org,"Oxylipins promote bacterial organization in microcolonies, increasing the ability of P. aeruginosa to form biofilms in vitro and in vivo.",E Martínez 2016,2016,2 genes,Martinez-2016-Oxylipins produced by Pseudomona,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8915,PHI:6820,UniProt,Q9I237,GenBank,AE004635_4,,,PAO1,PA2078,,,,,,PHI:6819,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),Oregon R,,,,diol synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27929111,PubMed,10.1038/ncomms13823,Nat Commun.2016 Dec 8;7:13823,jcampos-gomez@southernresearch.org,"Oxylipins promote bacterial organization in microcolonies, increasing the ability of P. aeruginosa to form biofilms in vitro and in vivo.",E Martínez 2016,2016,2 genes,Martinez-2016-Oxylipins produced by Pseudomona,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8916,PHI:6819,UniProt,Q9I238,GenBank,AE004635_3,,,PAO1,PA2077,,,,,,PHI:6820,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. longifolia (romaine hearts),,,leaf,diol synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27929111,PubMed,10.1038/ncomms13823,Nat Commun.2016 Dec 8;7:13823,jcampos-gomez@southernresearch.org,"Oxylipins promote bacterial organization in microcolonies, increasing the ability of P. aeruginosa to form biofilms in vitro and in vivo.",E Martínez 2016,2016,2 genes,Martinez-2016-Oxylipins produced by Pseudomona,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8917,PHI:6820,UniProt,Q9I237,GenBank,AE004635_4,,,PAO1,PA2078,,,,,,PHI:6819,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. longifolia (romaine hearts),,,leaf,diol synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27929111,PubMed,10.1038/ncomms13823,Nat Commun.2016 Dec 8;7:13823,jcampos-gomez@southernresearch.org,"Oxylipins promote bacterial organization in microcolonies, increasing the ability of P. aeruginosa to form biofilms in vitro and in vivo.",E Martínez 2016,2016,2 genes,Martinez-2016-Oxylipins produced by Pseudomona,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8918,PHI:6821,UniProt,A0A0N7IDU3,GenBank,ALJ54440,,,EHE-NE18,cnaA,,,,,,,1502,Clostridium perfringens,,EHE-NE18,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 308,,,ileal mucosa,putative adhesin-encoding gene,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene disruption,,,YVS,27938683,PubMed,10.1016/j.vetmic.2016.10.028,Vet Microbiol.2016 Dec 25;197:53-61,rob.moore@rmit.edu.au,Disruption of the cnaA gene led to reduced adherence to collagen types IV and V and gelatin.,B Wade 2016,2016,1 gene,Wade-2016-The adherent abilities of Clostridiu,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8919,PHI:6821,UniProt,A0A0N7IDU3,GenBank,ALJ54440,,,EHE-NE18,cnaA,,,,,,,1502,Clostridium perfringens,,56,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 308,,,ileal mucosa,putative adhesin-encoding gene,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene disruption,,,YVS,27938683,PubMed,10.1016/j.vetmic.2016.10.028,Vet Microbiol.2016 Dec 25;197:53-61,rob.moore@rmit.edu.au,Disruption of the cnaA gene led to reduced adherence to collagen types IV and V and gelatin.,B Wade 2016,2016,1 gene,Wade-2016-The adherent abilities of Clostridiu,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8920,PHI:6822,UniProt,Q5AF55,GenBank,AOW29018,,,SC5314,zcf15,chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene disruption; gene complementation,,,YVS,27932543,PubMed,10.1534/genetics.116.195024,Genetics. 2017 Feb;205(2):559-576,rpr@wpi.edu,Dysregulation of the biochemical nutritional pathways in zcf15/zcf15 and zcf29/zcf29 mutants results in their inability to respond to host-related stresses and thereby reduced virulence.,L Issi 2016,2016,2 genes,Issi-2016-Members of the Zinc Cluster Factor F,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8921,PHI:6823,UniProt,A0A1D8PRB7,GenBank,AOW30666,,,SC5314,zcf29,chromosome 7,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene disruption,,,YVS,27932543,PubMed,10.1534/genetics.116.195024,Genetics. 2017 Feb;205(2):559-576,rpr@wpi.edu,Dysregulation of the biochemical nutritional pathways in zcf15/zcf15 and zcf29/zcf29 mutants results in their inability to respond to host-related stresses and thereby reduced virulence.,L Issi 2016,2016,2 genes,Issi-2016-Members of the Zinc Cluster Factor F,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8922,PHI:6824,UniProt,P17778,GenBank,AAC62580,,,KIM5,YopM,,,,,,,632,Yersinia pestis,,KIM1001,bubonic plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,effector protein,,,pyrin pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911947,PubMed,10.1371/journal.ppat.1006035,PLoS Pathog. 2016 Dec 2;12(12):e1006035,Egil.Lien@umassmed.edu,Host gene alteration data available for Pyrin. YopM blocks YopE-induced Pyrin-mediated caspase-1 dependent IL-1beta/IL-18 production and cell death.,D Ratner 2016,2016,1 gene,Ratner-2016-The Yersinia pestis Effector YopM,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8923,PHI:6825,UniProt,E3Q2L6,GenBank,EFQ25317,,,M1.001,GPI12,,,,,,,31870,Colletotrichum graminicola,,M2,anthracnose (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf,N-acetylglucosaminylphosphatidylinositol deacetylase,,,glycosylphosphatidylinositol (GPI) synthesis pathway,loss of pathogenicity,,yes,,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; calcofluor white; KCl; sorbitol; sucrose,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; KCl: CHEBI:32588; sorbitol: CHEBI:17924,,,,,altered gene expression / gene regulation: silencing,,,YVS,27937175,PubMed,10.1094/MPMI-09-16-0175-R,Mol Plant Microbe Interact. 2016 Nov;29(11):889-901,holger.deising@landw.uni-halle.de,"RNAi strains showed drastic cell-wall defects, resulting in exploding infection cells on the plant surface and severe distortion of in planta-differentiated infection hyphae, including formation of intrahyphal hyphae.",E O G 2016,2016,3 genes,Oliveira-Garcia-2016-The Glycosylphosphatidyli,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8924,PHI:6826,UniProt,E3QI05,GenBank,EFQ30493,,,M1.001,GAA1,,,,,,,31870,Colletotrichum graminicola,,M2,anthracnose (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf,metallo-peptide-synthetase,,,glycosylphosphatidylinositol (GPI) synthesis pathway,loss of pathogenicity,,yes,,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; calcofluor white; KCl; sorbitol; sucrose,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; KCl: CHEBI:32588; sorbitol: CHEBI:17924,,,,,altered gene expression / gene regulation: silencing,,,YVS,27937175,PubMed,10.1094/MPMI-09-16-0175-R,Mol Plant Microbe Interact. 2016 Nov;29(11):889-901,holger.deising@landw.uni-halle.de,"RNAi strains showed drastic cell-wall defects, resulting in exploding infection cells on the plant surface and severe distortion of in planta-differentiated infection hyphae, including formation of intrahyphal hyphae.",E O G 2016,2016,3 genes,Oliveira-Garcia-2016-The Glycosylphosphatidyli,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8925,PHI:6827,UniProt,E3QJK7,GenBank,EFQ31045,,,M1.001,GPI8,,,,,,,31870,Colletotrichum graminicola,,M2,anthracnose (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf,cystein protease,,,glycosylphosphatidylinositol (GPI) synthesis pathway,loss of pathogenicity,,yes,,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; calcofluor white; KCl; sorbitol; sucrose,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; KCl: CHEBI:32588; sorbitol: CHEBI:17924,,,,,altered gene expression / gene regulation: silencing,,,YVS,27937175,PubMed,10.1094/MPMI-09-16-0175-R,Mol Plant Microbe Interact. 2016 Nov;29(11):889-901,holger.deising@landw.uni-halle.de,"RNAi strains showed drastic cell-wall defects, resulting in exploding infection cells on the plant surface and severe distortion of in planta-differentiated infection hyphae, including formation of intrahyphal hyphae.",E O G 2016,2016,3 genes,Oliveira-Garcia-2016-The Glycosylphosphatidyli,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8926,PHI:6828,UniProt,P43078,GenBank,AAC05307,,,,CPP1,,cpp1delta/cpp1delta::URA3,,,,,5476,Candida albicans,237561,SC5314,mycotic mastitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,mammary gland,mitogen-activated protein kinase tyrosine phosphatase,,,MAP kinase pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,9890266,PubMed,10.1111/j.1699-0463.1998.tb00257.x,APMIS.1998 Nov;106(11):1049-55,,Cpplp is involved in colonization at primary sites of infection.,F A Guhad 1998,1998,1 gene,Guhad-1998-Reduced pathogenicity of a Candida,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8927,PHI:6829,UniProt,Q8GA91,GenBank,CAD30218,,,,ascV,,,,,,,645,Aeromonas salmonicida,29491,subsp. salmonicida strain JF2267,furunculosis,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,head kidney,inner membrane protein of socket/cup of T3SS,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27923746,PubMed,10.1016/j.fsi.2016.12.006,Fish Shellfish Immunol.2017 Jan;60:334-345,francesco.origgi@vetsuisse.unibe.ch,"None of the fish challenged with a cured strain, JF2397, devoid of the plasmid encoding for T3SS and its associated toxins and effector molecules showed any sign of disease during the study.",F C Origgi 2016,2016,1 gene,Origgi-2016-Aeromonas salmonicida type III sec,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8928,PHI:6830,UniProt,P17778,GenBank,AAC62580,,,KIM5,YopM,,,,,,,632,Yersinia pestis,229193,91001,plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911947,PubMed,10.1371/journal.ppat.1006035,PLoS Pathog. 2016 Dec 2;12(12):e1006035,Egil.Lien@umassmed.edu,"YopM associates with NLRP3, and its CLD ligase motif mediates the activating K63-linked ubiquitylation of NLRP3, as a result, YopM modulates NLRP3-mediated cell necrosis.",D Ratner 2016,2016,1 gene,Wei-2016-The Yersinia Type III secretion effec,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8929,PHI:6831,UniProt,G2WSX9,GenBank,EGY17220,,,VdLs.17,Vd4LysM,chromosome 1,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Motelle,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8930,PHI:6831,UniProt,G2WSX9,GenBank,EGY17220,,,VdLs.17,Vd4LysM,chromosome 1,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8931,PHI:6831,UniProt,G2WSX9,GenBank,EGY17220,,,VdLs.17,Vd4LysM,chromosome 1,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8932,PHI:6831,UniProt,G2WSX9,GenBank,EGY17220,,,VdLs.17,Vd4LysM,chromosome 1,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8933,PHI:6832,UniProt,G2X444,GenBank,EGY23343,,,VdLs.17,Vd5LysM,chromosome 3,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Motelle,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8934,PHI:6832,UniProt,G2X444,GenBank,EGY23343,,,VdLs.17,Vd5LysM,chromosome 3,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8935,PHI:6832,UniProt,G2X444,GenBank,EGY23343,,,VdLs.17,Vd5LysM,chromosome 3,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8936,PHI:6832,UniProt,G2X444,GenBank,EGY23343,,,VdLs.17,Vd5LysM,chromosome 3,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8937,PHI:6833,UniProt,G2XA95,GenBank,EGY15834,,,VdLs.17,Vd6LysM,chromosome 5,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Motelle,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8938,PHI:6833,UniProt,G2XA95,GenBank,EGY15834,,,VdLs.17,Vd6LysM,chromosome 5,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8939,PHI:6833,UniProt,G2XA95,GenBank,EGY15834,,,VdLs.17,Vd6LysM,chromosome 5,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8940,PHI:6833,UniProt,G2XA95,GenBank,EGY15834,,,VdLs.17,Vd6LysM,chromosome 5,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8941,PHI:6834,UniProt,G2X4U8,GenBank,EGY23742,,,VdLs.17,Vd2LysM,chromosome 4,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Motelle,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8942,PHI:6834,UniProt,G2X4U8,GenBank,EGY23742,,,VdLs.17,Vd2LysM,chromosome 4,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8943,PHI:6834,UniProt,G2X4U8,GenBank,EGY23742,,,VdLs.17,Vd2LysM,chromosome 4,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8944,PHI:6834,UniProt,G2X4U8,GenBank,EGY23742,,,VdLs.17,Vd2LysM,chromosome 4,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27911046,PubMed,10.1111/mpp.12520,Mol Plant Pathol. 2016 Dec 2,bart.thomma@wur.nl,"The targeted deletion of the individual LysM effector genes (Vd4LysM, Vd5LysM and Vd6LysM) in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Remarkably, the lineage-specific effector (Vd2LysM) contributes to virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or on N. benthamiana.",A Kombrink 2016,2016,4 genes,Kombrink-2016-Verticillium dahliae LysM effect,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8945,PHI:6835,UniProt,T2PUN5,GenBank,AIN69423,,,SEJ,ompA,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain CVCC3378,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,liver; blood; spleen; lung; kidney; small intestine,outer membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,27938704,PubMed,10.1016/j.tvjl.2016.10.009,Vet J. 2016 Dec;218:19-26,gsong@yzu.edu.cn,"There were no significant differences between the wild-type and ompA and pgtE mutants in a series of in vitro assays, in contrast, in vivo competition assays revealed that ompA and pgtE mutants underwent attenuated growth in organs of a wild-type strain. cardiac blood",Y Zhou 2016,2016,2 genes,Zhou-2016-Evaluation of ompA and pgtE genes in,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8946,PHI:6836,,no data found,GenBank,CAR33967,,,P125109,pgtE,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain CVCC3378,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,liver; blood; spleen; lung; kidney; small intestine,outer membrane protease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,27938704,PubMed,10.1016/j.tvjl.2016.10.009,Vet J. 2016 Dec;218:19-26,gsong@yzu.edu.cn,"There were no significant differences between the wild-type and ompA and pgtE mutants in a series of in vitro assays, in contrast, in vivo competition assays revealed that ompA and pgtE mutants underwent attenuated growth in organs of a wild-type strain. cardiac blood",Y Zhou 2016,2016,2 genes,Zhou-2016-Evaluation of ompA and pgtE genes in,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8947,PHI:6837,UniProt,A0A1D8PMK1,GenBank,AOW29372,,,SC5314,CEK1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,mammary gland,mitogen-activated protein kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,9741091,PubMed,10.1111/j.1574-6968.1998.tb13194.x,FEMS Microbiol Lett. 1998 Sep 1;166(1):135-9,,Candida albicans strains with a deletion of the mitogen-activated protein kinase CEK1 gene are defective in the yeast to hyphal transition on solid surfaces in vitro.,F A Guhad 1998,1998,1 gene,Guhad-1998-Mitogen-activated protein kinase-de,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8948,PHI:6838,UniProt,Q75WC5,GenBank,BAC98434,,,Pg-10,gyrA,,Ser83Arg,,,,,337,Burkholderia glumae,,Pg-10,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),cv. Koshihikari,,,spikelet,DNA gyrase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,17194844,PubMed,10.1128/AEM.02400-06,Appl Environ Microbiol. 2007 Feb;73(4):1114-9,yhikichi@cc.kochi-u.ac.jp,"Oxolinic acid application may lead to an increase in the ability of GyrA recombinants, especially those with Ser83Arg in GyrA, to grow in rice spikelets.",Y Maeda 2007,2007,1 gene,Maeda-2007-Amino acid substitutions in GyrA of,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8949,PHI:6838,UniProt,Q75WC5,GenBank,BAC98434,,,Pg-10,gyrA,,Gly81Cys or Gly81Asp or Asp87Gly or Asp87Asn,,,,,337,Burkholderia glumae,,Pg-10,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),cv. Koshihikari,,,spikelet,DNA gyrase,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,17194844,PubMed,10.1128/AEM.02400-06,Appl Environ Microbiol. 2007 Feb;73(4):1114-9,yhikichi@cc.kochi-u.ac.jp,"Oxolinic acid application may lead to an increase in the ability of GyrA recombinants, especially those with Ser83Arg in GyrA, to grow in rice spikelets.",Y Maeda 2007,2007,1 gene,Maeda-2007-Amino acid substitutions in GyrA of,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8950,PHI:6838,UniProt,Q75WC5,GenBank,BAC98434,,,Pg-10,gyrA,,Asp82Gly,,,,,337,Burkholderia glumae,,Pg-10,bacterial grain rot,monocots,4530,Oryza sativa (related: rice),cv. Koshihikari,,,spikelet,DNA gyrase,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,17194844,PubMed,10.1128/AEM.02400-06,Appl Environ Microbiol. 2007 Feb;73(4):1114-9,yhikichi@cc.kochi-u.ac.jp,"Oxolinic acid application may lead to an increase in the ability of GyrA recombinants, especially those with Ser83Arg in GyrA, to grow in rice spikelets.",Y Maeda 2007,2007,1 gene,Maeda-2007-Amino acid substitutions in GyrA of,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8951,PHI:6839,UniProt,Q5GZB8,GenBank,AAW75953,,,KACC10331,pglA,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,polygalacturonase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,27907079,PubMed,10.1371/journal.pone.0166396,PLoS One. 2016 Dec 1;11(12):e0166396,sonti@ccmb.res.in,"The polygalacturonase mutant pglA was completely deficient in degrading the substrate Na-polygalacturonicacid (PGA), whereas, strains carrying mutations in the pmt, pel and pelL genes were as efficient as wild type Xoo(BXO43) in cleaving PGA.",L Tayi 2016,2016,4 genes,Tayi-2016-Identification of Pectin Degrading E,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8952,PHI:6840,UniProt,Q5GZC1,GenBank,AAW75950,,,KACC10331,pmt,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,pectin methyl esterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,27907079,PubMed,10.1371/journal.pone.0166396,PLoS One. 2016 Dec 1;11(12):e0166396,sonti@ccmb.res.in,"The polygalacturonase mutant pglA was completely deficient in degrading the substrate Na-polygalacturonicacid (PGA), whereas, strains carrying mutations in the pmt, pel and pelL genes were as efficient as wild type Xoo(BXO43) in cleaving PGA.",L Tayi 2016,2016,4 genes,Tayi-2016-Identification of Pectin Degrading E,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8953,PHI:6841,UniProt,Q5H4P5,GenBank,AAW74075,,,KACC10331,pel,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,pectate lyase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,27907079,PubMed,10.1371/journal.pone.0166396,PLoS One. 2016 Dec 1;11(12):e0166396,sonti@ccmb.res.in,"The polygalacturonase mutant pglA was completely deficient in degrading the substrate Na-polygalacturonicacid (PGA), whereas, strains carrying mutations in the pmt, pel and pelL genes were as efficient as wild type Xoo(BXO43) in cleaving PGA.",L Tayi 2016,2016,4 genes,Tayi-2016-Identification of Pectin Degrading E,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8954,PHI:6842,UniProt,Q5H0K2,GenBank,AAW75519,,,KACC10331,pelL,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,pectate lyase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,27907079,PubMed,10.1371/journal.pone.0166396,PLoS One. 2016 Dec 1;11(12):e0166396,sonti@ccmb.res.in,"The polygalacturonase mutant pglA was completely deficient in degrading the substrate Na-polygalacturonicacid (PGA), whereas, strains carrying mutations in the pmt, pel and pelL genes were as efficient as wild type Xoo(BXO43) in cleaving PGA.",L Tayi 2016,2016,4 genes,Tayi-2016-Identification of Pectin Degrading E,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8955,PHI:6843,UniProt,P43068,GenBank,CAA54129,,,1001 (ATCC 64385),mkc1,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; brain,mitogen-activated protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,16179009,PubMed,10.1111/j.1365-3083.2005.01657.x,Scand J Immunol. 2005 Sep;62(3):224-33,rosaliad@farm.ucm.es,"Host gene alteration data available for IFN-gamma and IL-4. The mutant strain displayed a greater susceptibility to nitric oxide (NO), a reduced inhibitory effect on macrophage NO production and an increased capacity of macrophage stimulation by cell wall extracts.",G Molero 2005,2005,1 gene,Molero-2005-The importance of the phagocytes',BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8956,PHI:6843,UniProt,P43068,GenBank,CAA54129,,,1001 (ATCC 64385),mkc1,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),DBA/2,,,kidney; brain,mitogen-activated protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,16179009,PubMed,10.1111/j.1365-3083.2005.01657.x,Scand J Immunol. 2005 Sep;62(3):224-33,rosaliad@farm.ucm.es,"Host gene alteration data available for IFN-gamma and IL-4. The mutant strain displayed a greater susceptibility to nitric oxide (NO), a reduced inhibitory effect on macrophage NO production and an increased capacity of macrophage stimulation by cell wall extracts.",G Molero 2005,2005,1 gene,Molero-2005-The importance of the phagocytes',BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8957,PHI:6844,UniProt,Q87CH2,GenBank,AAO28954,,,Temecula1,dinJ,,,,,,PHI:6845,2371,Xylella fastidiosa,,Stag's Leap,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,xylem,"antitoxin, DNA-damage-inducible protein",,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation,,,YVS,27938243,PubMed,10.1094/PHYTO-10-16-0374-R,Phytopathology. 2016 Dec 12,lindsey.burbank@ars.usda.gov,"DinJ/RelE acts to prevent excessive population growth, contributing to the ability of the pathogen to spread systemically without completely blocking the xylem vessels, and increasing probability of acquisition by the insect vector.",L P Burbank 2016,2016,2 genes,Burbank-2016-The DinJ_RelE toxin-antitoxin sys,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8958,PHI:6845,UniProt,A0A0E3C5K7,GenBank,KGM19906,,,ATCC 35879,relE,,,,,,PHI:6844,2371,Xylella fastidiosa,,Stag's Leap,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,xylem,endoribonuclease toxin,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation,,,YVS,27938243,PubMed,10.1094/PHYTO-10-16-0374-R,Phytopathology. 2016 Dec 12,lindsey.burbank@ars.usda.gov,"DinJ/RelE acts to prevent excessive population growth, contributing to the ability of the pathogen to spread systemically without completely blocking the xylem vessels, and increasing probability of acquisition by the insect vector.",L P Burbank 2016,2016,2 genes,Burbank-2016-The DinJ_RelE toxin-antitoxin sys,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8959,PHI:6846,UniProt,K3V774,GenBank,EKJ67643,,,CS3096,TRI5,,,,,,,101028,Fusarium pseudograminearum,1028729,CS3096,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kennedy,,,leaf,trichodiene synthase,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27941094,PubMed,10.1093/aob/mcw207,Ann Bot. 2016 Dec 10. pii: mcw207,jonathan.powell@csiro.au,The differences observed in virulence between isolates of F. pseudograminearum suggest many different virulence factors contributing quantitatively to virulence of this pathogen and that in highly aggressive strains the loss of one of these is not as detrimental to the pathogen asit is in a less aggressive isolate.,J J Powell 2016,2016,1 gene,Powell-2016-The Fusarium crown rot pathogen Fu,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8960,PHI:6846,UniProt,K3V774,GenBank,EKJ67643,,,CS3096,TRI5,,,,,,,101028,Fusarium pseudograminearum,1318457,CS3427,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kennedy,,,leaf,trichodiene synthase,,,deoxynivalenol biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27941094,PubMed,10.1093/aob/mcw207,Ann Bot. 2016 Dec 10. pii: mcw207,jonathan.powell@csiro.au,The differences observed in virulence between isolates of F. pseudograminearum suggest many different virulence factors contributing quantitatively to virulence of this pathogen and that in highly aggressive strains the loss of one of these is not as detrimental to the pathogen asit is in a less aggressive isolate.,J J Powell 2016,2016,1 gene,Powell-2016-The Fusarium crown rot pathogen Fu,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8961,PHI:6847,UniProt,D7FGA7,GenBank,CBI67214,,,B8,niuB1,,,,,,PHI:6848,210,Helicobacter pylori,544406,B128-S,gastric infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,stomach,ABC transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27923069,PubMed,10.1371/journal.ppat.1006018,PLoS Pathog. 2016 Dec 6;12(12):e1006018,hdereuse@pasteur.fr,Urease activation by nickel depends on the NiuBDE and NixA systems and NiuBDE is essential for colonization of a mouse model by H. pylori.,F Fischer 2016,2016,4 genes,Fischer-2016-Characterization in Helicobacter,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8962,PHI:6848,UniProt,D7FGA8,GenBank,CBI67215,,,B8,niuB2,,,,,,PHI:6847,210,Helicobacter pylori,544406,B128-S,gastric infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,stomach,ABC transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27923069,PubMed,10.1371/journal.ppat.1006018,PLoS Pathog. 2016 Dec 6;12(12):e1006018,hdereuse@pasteur.fr,Urease activation by nickel depends on the NiuBDE and NixA systems and NiuBDE is essential for colonization of a mouse model by H. pylori.,F Fischer 2016,2016,4 genes,Fischer-2016-Characterization in Helicobacter,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8963,PHI:6849,UniProt,D7FDG3,GenBank,CBI66220,,,B8,niuD,,,,,,,210,Helicobacter pylori,544406,B128-S,gastric infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,stomach,ABC transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27923069,PubMed,10.1371/journal.ppat.1006018,PLoS Pathog. 2016 Dec 6;12(12):e1006018,hdereuse@pasteur.fr,Urease activation by nickel depends on the NiuBDE and NixA systems and NiuBDE is essential for colonization of a mouse model by H. pylori.,F Fischer 2016,2016,4 genes,Fischer-2016-Characterization in Helicobacter,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8964,PHI:6850,UniProt,Q48262,GenBank,CAA88633,,,ATCC 43504,nixA,,,,,,,210,Helicobacter pylori,544406,B128-S,gastric infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,stomach,high-affinity nickel-transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27923069,PubMed,10.1371/journal.ppat.1006018,PLoS Pathog. 2016 Dec 6;12(12):e1006018,hdereuse@pasteur.fr,Urease activation by nickel depends on the NiuBDE and NixA systems and NiuBDE is essential for colonization of a mouse model by H. pylori.,F Fischer 2016,2016,4 genes,Fischer-2016-Characterization in Helicobacter,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8965,PHI:6851,UniProt,A0A1J0M1X4,GenBank,APD13840,,,12.0.082,MPG1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hydrophobin,,,"PMK1 MAPK, cAMP response and nitrogen repression pathways",reduced virulence,,yes,,,,,,,reduced,no,,,,,,,gene mutation; gene complementation,,,YVS,12481998,PubMed,10.1094/MPMI.2002.15.12.1253,Mol Plant Microbe Interact.2002 Dec;15(12):1253-67,N.J.Talbot@exeter.ac.uk,Three regions of the MPG1 promoter were identified which are required for high-level expression of MPG1 during appressorium formation and are necessary for the biological activity of the MPG1 hydrophobin during spore formation and plant infection.,D M Soanes 2002,2002,1 gene,Soanes-2002-Regulation of the MPG1 hydrophobin,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8966,PHI:6852,UniProt,Q71RX8,GenBank,AEX00910,,,8934,SpvD,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,T3SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27789710,PubMed,10.1074/jbc.M116.752782,J Biol Chem. 2016 Dec 9; 291(50): 25853-25863,s.hare@imperial.ac.uk,SpvDG161 variant more potently inhibited NF-B-mediated immune responses in cells in vitro and increased virulence of serovar Typhimurium in mice.,G J Grabe 2016,2016,1 gene,Grabe-2016-The Salmonella Effector SpvD Is a C,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8967,PHI:6853,UniProt,P0C1A3,GenBank,ADM99550,,,3937,PelA,,,,,,PHI:6854; PHI:6855,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27925401,PubMed,10.1111/mpp.12522,Mol Plant Pathol. 2016 Dec 7,expert@agroparistech.fr,Host gene alteration data available for atrbohD and atrbohD/atrbohF. A significant reduction in ROS and callose formation was observed with a bacterial mutant in which genes encoding five pectate lyases (Pels) were disrupted.,D Expert 2016,2016,7 genes,Expert-2016-Dickeya dadantii pectic enzymes ne,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8968,PHI:6854,UniProt,E0SAZ3,GenBank,ADM99552,,,3937,PelD,,,,,,PHI:6853; PHI:6855,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27925401,PubMed,10.1111/mpp.12522,Mol Plant Pathol. 2016 Dec 7,expert@agroparistech.fr,Host gene alteration data available for atrbohD and atrbohD/atrbohF. A significant reduction in ROS and callose formation was observed with a bacterial mutant in which genes encoding five pectate lyases (Pels) were disrupted.,D Expert 2016,2016,7 genes,Expert-2016-Dickeya dadantii pectic enzymes ne,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8969,PHI:6855,UniProt,P0C1A5,GenBank,ADM99551,,,3937,PelE,,,,,,PHI:6853; PHI:6854,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27925401,PubMed,10.1111/mpp.12522,Mol Plant Pathol. 2016 Dec 7,expert@agroparistech.fr,Host gene alteration data available for atrbohD and atrbohD/atrbohF. A significant reduction in ROS and callose formation was observed with a bacterial mutant in which genes encoding five pectate lyases (Pels) were disrupted.,D Expert 2016,2016,7 genes,Expert-2016-Dickeya dadantii pectic enzymes ne,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8970,PHI:6856,UniProt,E0SJQ6,GenBank,ADN00345,,,3937,PelB,,,,,,PHI:6857,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27925401,PubMed,10.1111/mpp.12522,Mol Plant Pathol. 2016 Dec 7,expert@agroparistech.fr,Host gene alteration data available for atrbohD and atrbohD/atrbohF. A significant reduction in ROS and callose formation was observed with a bacterial mutant in which genes encoding five pectate lyases (Pels) were disrupted.,D Expert 2016,2016,7 genes,Expert-2016-Dickeya dadantii pectic enzymes ne,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8971,PHI:6857,UniProt,E0SJQ7,GenBank,ADN00346,,,3937,PelC,,,,,,PHI:6856,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27925401,PubMed,10.1111/mpp.12522,Mol Plant Pathol. 2016 Dec 7,expert@agroparistech.fr,Host gene alteration data available for atrbohD and atrbohD/atrbohF. A significant reduction in ROS and callose formation was observed with a bacterial mutant in which genes encoding five pectate lyases (Pels) were disrupted.,D Expert 2016,2016,7 genes,Expert-2016-Dickeya dadantii pectic enzymes ne,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8972,PHI:6858,UniProt,E0SM75,GenBank,ADM99410,,,3937,PelI,,PelIQ227A,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27925401,PubMed,10.1111/mpp.12522,Mol Plant Pathol. 2016 Dec 7,expert@agroparistech.fr,Host gene alteration data available for atrbohD and atrbohD/atrbohF. A significant reduction in ROS and callose formation was observed with a bacterial mutant in which genes encoding five pectate lyases (Pels) were disrupted.,D Expert 2016,2016,7 genes,Expert-2016-Dickeya dadantii pectic enzymes ne,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8973,PHI:6859,UniProt,Q01564,GenBank,ADM99377,,,3937,OutC,,outC::uidA-Km,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type II secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27925401,PubMed,10.1111/mpp.12522,Mol Plant Pathol. 2016 Dec 7,expert@agroparistech.fr,Host gene alteration data available for atrbohD and atrbohD/atrbohF. A significant reduction in ROS and callose formation was observed with a bacterial mutant in which genes encoding five pectate lyases (Pels) were disrupted.,D Expert 2016,2016,7 genes,Expert-2016-Dickeya dadantii pectic enzymes ne,BATCH_064B,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8974,PHI:6860,UniProt,Q6GD52,GenBank,CAG41810,,,MSSA476,tirS,,,,,,,1280,Staphylococcus aureus,,HT20030749,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,28060920,PubMed,10.1371/journal.ppat.1006092,PLoS Pathog.2017 Jan 6;13(1):e1006092,gerard.lina@univ-lyon1.fr,Infection with deltatirS strain resulted in larger lesions compared with the WT strain.,S Patot 2017,2017,1 gene,Patot-2017-The TIR Homologue Lies near Resista,BATCH_065A,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8975,PHI:6861,UniProt,Q4WLP9,GenBank,EAL89115,,,Af293,rbdA,chromosome 6,,,,,,746128,Aspergillus fumigatus,1266464,akuBKU80,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,rhomboid family putative protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27068092,PubMed,10.1128/IAI.00011-16,Infect Immun. 2016 Jun; 84(6): 1866-1878,nosherov@post.tau.ac.il,The deltarbdAand deltasrbAmutant strains do not form a biofilm.,Y Vaknin 2016,2016,2 genes,Vaknin-2016-Identification and characterizatio,BATCH_065A,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8976,PHI:6861,UniProt,Q4WLP9,GenBank,EAL89115,,,Af293,rbdA,chromosome 6,,,,,,746128,Aspergillus fumigatus,1266464,akuBKU80,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,rhomboid family putative protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27068092,PubMed,10.1128/IAI.00011-16,Infect Immun. 2016 Jun; 84(6): 1866-1878,nosherov@post.tau.ac.il,The deltarbdAand deltasrbAmutant strains do not form a biofilm.,Y Vaknin 2016,2016,2 genes,Vaknin-2016-Identification and characterizatio,BATCH_065A,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8977,PHI:6862,UniProt,Q4WIN1,GenBank,EAL87224,,,Af293,srbA,chromosome 2,,,,,,746128,Aspergillus fumigatus,1266464,akuBKU80,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sterol regulatory element binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27068092,PubMed,10.1128/IAI.00011-16,Infect Immun. 2016 Jun; 84(6): 1866-1878,nosherov@post.tau.ac.il,The deltarbdAand deltasrbAmutant strains do not form a biofilm.,Y Vaknin 2016,2016,2 genes,Vaknin-2016-Identification and characterizatio,BATCH_065A,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8978,PHI:6862,UniProt,Q4WIN1,GenBank,EAL87224,,,Af293,srbA,chromosome 2,,,,,,746128,Aspergillus fumigatus,1266464,akuBKU80,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,sterol regulatory element binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27068092,PubMed,10.1128/IAI.00011-16,Infect Immun. 2016 Jun; 84(6): 1866-1878,nosherov@post.tau.ac.il,The deltarbdAand deltasrbAmutant strains do not form a biofilm.,Y Vaknin 2016,2016,2 genes,Vaknin-2016-Identification and characterizatio,BATCH_065A,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8979,PHI:6863,UniProt,A1KT19,GenBank,CAM10001,,,FAM18,pnp,,,,,,,487,Neisseria meningitidis,,FAM20,meningococcal infection,rodents,10090,Mus musculus (related: house mouse),hCD46Ge,,,blood,polynucleotide phosphorylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26930706,PubMed,10.1128/IAI.01463-15,Infect Immun.2016 Apr 22;84(5):1501-13,ann-beth.jonsson@su.se,Deletion of the gene encoding PNPase leads to hyperaggregation and increased adhesion to epithelial cells.,J Engman 2016,2016,1 gene,Engman-2016-Neisseria meningitidis polynucleot,BATCH_065A,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8980,PHI:6864,UniProt,D2TT37,GenBank,CBG87859,,,ICC168,NleB1,,"NleBE253A, NleBY219A",,,,,67825,Citrobacter rodentium,,ICC169,colitis,rodents,10090,Mus musculus (related: house mouse),B6;129S7-Dbh<tm1Rpa>/Rpa,,,intestine,T3SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,26883593,PubMed,10.1128/IAI.01523-15,Infect Immun.2016 Apr 22;84(5):1346-60,hartland@unimelb.edu.au,Amino acid residues Y219 and E253 are required for NleB function during Citrobacter rodentiuminfection of mice.,T W F Lung 2016,2016,1 gene,Wong Fok Lung-2016-Mutagenesis and functional,BATCH_065A,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8981,PHI:6865,UniProt,Q9LAB5,GenBank,AAF66692,,,M804,IsaB,,deltaisaB::erm,,,,,1280,Staphylococcus aureus,,10833,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),ICR,,,skin,immunodominant surface antigen,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,26134948,PubMed,10.1038/jid.2015.254,J Invest Dermatol.2015 Nov;135(11):2714-22,chunming@ucsd.edu,IsaB diminishes autophagic flux to enhance bacterial survival in cells.,P F Liu 2015,2015,1 gene,Liu-2015-IsaB Inhibits Autophagic Flux to Prom,BATCH_065A,2017-02-01,MC,,,,,,,,,,,,,
,,Record 8982,PHI:6866,UniProt,B3H2N1,,,,,Serotype 7 strain AP76,agt,,,,,,,715,Actinobacillus pleuropneumoniae,,serotype 15 strain HS143,pleuropneumonia (pig),primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,alpha-6-glucosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28077594,PubMed,10.1098/rsob.160212,Open Biol. 2017 Jan;7(1). pii: 160212,brendan.wren@lshtm.ac.uk,NGT and a6GlcT are required for adhesion of Actinobacillus pleuropneumoniae HS143 to A549 cell lines.,J Cuccui 2017,2017,2 genes,Cuccui-2017-The N-linking glycosylation system,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8983,PHI:6867,UniProt,B3H2N2,,,,,Serotype 7 strain AP76,ngt,,,,,,,715,Actinobacillus pleuropneumoniae,,serotype 15 strain HS143,pleuropneumonia (pig),primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,N-linked glucosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28077594,PubMed,10.1098/rsob.160212,Open Biol. 2017 Jan;7(1). pii: 160212,brendan.wren@lshtm.ac.uk,NGT and a6GlcT are required for adhesion of Actinobacillus pleuropneumoniae HS143 to A549 cell lines.,J Cuccui 2017,2017,2 genes,Cuccui-2017-The N-linking glycosylation system,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8984,PHI:6868,UniProt,G4ZHR2,GenBank,EGZ16757,,,P6497,PsXEG1,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,root; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28082413,PubMed,10.1126/science.aai7919,Science. 2017 Feb 17;355(6326):710-714,wangyc@njau.edu.cn,Host gene alteration data available for GmGIP1. GmGIP1 inhibits PsXEG1's contribution to P. sojae virulence.,Z Ma 2017,2017,2 genes,Ma-2017-A paralogous decoy protects Phytophtho,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8985,PHI:6869,UniProt,G4ZHR3,GenBank,XP_009525816,,,P6497,PsXLP1,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,root; hypocotyl,putative glucanase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28082413,PubMed,10.1126/science.aai7919,Science. 2017 Feb 17;355(6326):710-714,wangyc@njau.edu.cn,Host gene alteration data available for GmGIP1. GmGIP1 inhibits PsXEG1's contribution to P. sojae virulence.,Z Ma 2017,2017,2 genes,Ma-2017-A paralogous decoy protects Phytophtho,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8986,PHI:6870,UniProt,A0A165G9C3,GenBank,AMY26905,,,SF1,yeaZ,,,,,,,669,Vibrio harveyi,,SF-1,luminous vibriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,peritoneum,resuscitation-promoting factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,27966258,PubMed,10.1111/jam.13342,J Appl Microbiol. 2017 Feb;122(2):338-346,Li-2017-Promoting resuscitation of viable but,Disruption of yeaZ did not appear to affect the resuscitation of viable but nonculturable cells.,Y Li 2017,2017,1 gene,Li-2017-Promoting resuscitation of viable but,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8987,PHI:6871,UniProt,J9VUY6,GenBank,AFR98073,,,H99,gua1,chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung,GMP synthase,,,purine biosynthesis,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28062578,PubMed,10.1074/jbc.M116.767533,J Biol Chem. 2017 Feb 17;292(7):3049-3059,jafraser@uq.edu.au,"In the absence of GMP synthase, C. neoformans becomes a guanine auxotroph, the production of key virulence factors is compromised, and the ability to infect nematodes and mice is abolished.",J L Chitty 2017,2017,1 gene,Chitty-2017-GMP Synthase is Required for Virul,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8988,PHI:6871,UniProt,J9VUY6,GenBank,AFR98073,,,H99,gua1,chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,GMP synthase,,,purine biosynthesis,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28062578,PubMed,10.1074/jbc.M116.767533,J Biol Chem. 2017 Feb 17;292(7):3049-3059,jafraser@uq.edu.au,"In the absence of GMP synthase, C. neoformans becomes a guanine auxotroph, the production of key virulence factors is compromised, and the ability to infect nematodes and mice is abolished.",J L Chitty 2017,2017,1 gene,Chitty-2017-GMP Synthase is Required for Virul,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8989,PHI:6872,UniProt,Q2UEH7,,,,,ATCC 42149 / RIB 40,atrR,,,,,,,746128,Aspergillus fumigatus,,Af293,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneum,Zn2-Cys6 transcription factor,,,ergosterol biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28052140,PubMed,10.1371/journal.ppat.1006096,PLoS Pathog.2017 Jan 4;13(1):e1006096,gomi@biochem.tohoku.ac.jp,The atrR deletion mutant showed impaired growth under hypoxic conditions and attenuation of virulence in murine infection model for aspergillosis.,D Hagiwara 2017,2017,2 genes,Hagiwara-2017-A Novel Zn2-Cys6 Transcription F,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8990,PHI:6873,UniProt,Q4WIN1,GenBank,EAL87224,,,Af293,srbA,,,,,,,746128,Aspergillus fumigatus,,Af293,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneum,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28052140,PubMed,10.1371/journal.ppat.1006096,PLoS Pathog.2017 Jan 4;13(1):e1006096,gomi@biochem.tohoku.ac.jp,The atrR deletion mutant showed impaired growth under hypoxic conditions and attenuation of virulence in murine infection model for aspergillosis.,D Hagiwara 2017,2017,2 genes,Hagiwara-2017-A Novel Zn2-Cys6 Transcription F,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8991,PHI:6872,UniProt,Q2UEH7,,,,,ATCC 42149 / RIB 40,atrR,,,,,,,746128,Aspergillus fumigatus,,AfS35,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneum,Zn2-Cys6 transcription factor,,,ergosterol biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28052140,PubMed,10.1371/journal.ppat.1006096,PLoS Pathog.2017 Jan 4;13(1):e1006096,gomi@biochem.tohoku.ac.jp,The atrR deletion mutant showed impaired growth under hypoxic conditions and attenuation of virulence in murine infection model for aspergillosis.,D Hagiwara 2017,2017,2 genes,Hagiwara-2017-A Novel Zn2-Cys6 Transcription F,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8992,PHI:6873,UniProt,Q4WIN1,GenBank,EAL87224,,,Af293,srbA,,,,,,,746128,Aspergillus fumigatus,,AfS35,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneum,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28052140,PubMed,10.1371/journal.ppat.1006096,PLoS Pathog.2017 Jan 4;13(1):e1006096,gomi@biochem.tohoku.ac.jp,The atrR deletion mutant showed impaired growth under hypoxic conditions and attenuation of virulence in murine infection model for aspergillosis.,D Hagiwara 2017,2017,2 genes,Hagiwara-2017-A Novel Zn2-Cys6 Transcription F,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8993,PHI:6872,UniProt,Q2UEH7,,,,,ATCC 42149 / RIB 40,atrR,,,,,,PHI:6872,746128,Aspergillus fumigatus,,AfS35,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneum,Zn2-Cys6 transcription factor,,,ergosterol biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28052140,PubMed,10.1371/journal.ppat.1006096,PLoS Pathog.2017 Jan 4;13(1):e1006096,gomi@biochem.tohoku.ac.jp,The atrR deletion mutant showed impaired growth under hypoxic conditions and attenuation of virulence in murine infection model for aspergillosis.,D Hagiwara 2017,2017,2 genes,Hagiwara-2017-A Novel Zn2-Cys6 Transcription F,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8994,PHI:6873,UniProt,Q4WIN1,GenBank,EAL87224,,,Af293,srbA,,,,,,PHI:6871,746128,Aspergillus fumigatus,,AfS35,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneum,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28052140,PubMed,10.1371/journal.ppat.1006096,PLoS Pathog.2017 Jan 4;13(1):e1006096,gomi@biochem.tohoku.ac.jp,The atrR deletion mutant showed impaired growth under hypoxic conditions and attenuation of virulence in murine infection model for aspergillosis.,D Hagiwara 2017,2017,2 genes,Hagiwara-2017-A Novel Zn2-Cys6 Transcription F,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8995,PHI:6874,UniProt,G4NCH6,GenBank,XP_003717857,,,70-15,mopex14/17,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,peroxin,,,peroxisome biogenesis,reduced virulence,,yes,yes,,,reduced,,reduced,reduced,no,H2O2; methyl viologen; Congo red,H2O2: CHEBI:16240; methyl viologen: CHEBI:28786; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,27571711,PubMed,10.1111/mpp.12487,Mol Plant Pathol.2016 Aug 29,sungc01@sina.com,"MoPEX14/17 plays an essential role in the import of PTS1 proteins, as a consequence, participates in the lipid degradation, ROS elimination and cell wall integration.",L Li 2016,2016,1 gene,"Li-2016-Pex14_17, a filamentous fungi specific",BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8996,PHI:6874,UniProt,G4NCH6,GenBank,XP_003717857,,,70-15,mopex14/17,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,peroxin,,,peroxisome biogenesis,reduced virulence,,yes,yes,,,reduced,,reduced,reduced,no,H2O2; methyl viologen; Congo red,H2O2: CHEBI:16240; methyl viologen: CHEBI:28786; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,27571711,PubMed,10.1111/mpp.12487,Mol Plant Pathol.2016 Aug 29,sungc01@sina.com,"MoPEX14/17 plays an essential role in the import of PTS1 proteins, as a consequence, participates in the lipid degradation, ROS elimination and cell wall integration.",L Li 2016,2016,1 gene,"Li-2016-Pex14_17, a filamentous fungi specific",BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8997,PHI:6875,UniProt,J4KQD8,GenBank,EJP69029,,,ARSEF 2860,BbVmaH,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,vacuolarATPasesubunitH,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,H2O2; NaCl; menadione; Congo red,H2O2: CHEBI:16240; NaCl: CHEBI:26710; menadione: CHEBI:28869; Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,YVS,28011319,PubMed,10.1016/j.fgb.2016.12.004,Fungal Genet Biol.2017 Jan;98:52-60,mgfeng@zju.edu.cn,"Deletion of BbvmaH resulted in elevated vacuolar pH, increased Ca2+ level in cytosol but not in vacuoles, accelerated culture acidification and reduced accumulation of extracellular ammonia.",J Zhu 20172017,2017,1 gene,Zhu-2017-Effect of vacuolar ATPase subunit H (,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8998,PHI:6876,UniProt,A0A0H3JWX3,GenBank,BAB58477,,,Mu50,rpiRC,,,,,,,1280,Staphylococcus aureus,,SA564,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,lung; liver; kidney,effector protein,,,pentose phosphate pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27113358,PubMed,10.1128/IAI.00285-16,Infect Immun. 2016 Jul; 84(7): 2031-2041,rosmarie.gaupp@uks.eu,RpiRc attenuates staphylococcal pneumonia and abscess formation.,R Gaupp 2016,2016,1 gene,Gaupp-2016-RpiRc is a pleiotropic effector of,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 8999,PHI:6877,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,,672,Vibrio vulnificus,,CMCP6rif,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,cytolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28060924,PubMed,10.1371/journal.ppat.1006119,PLoS Pathog. 2017 Jan; 13(1): e1006119,k-satchell@northwestern.edu,The MARTX effector domain region is essential for bacterial dissemination from the intestine.,H E Gavin 2017,2017,2 genes,Gavin-2017-The Effector Domain Region of the V,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9000,PHI:6877,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:6877,672,Vibrio vulnificus,,CMCP6rif,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,cytolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28060924,PubMed,10.1371/journal.ppat.1006119,PLoS Pathog. 2017 Jan; 13(1): e1006119,k-satchell@northwestern.edu,The MARTX effector domain region is essential for bacterial dissemination from the intestine.,H E Gavin 2017,2017,2 genes,Gavin-2017-The Effector Domain Region of the V,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9001,PHI:6878,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,,,,,PHI:6876,672,Vibrio vulnificus,,CMCP6rif,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,MARTX cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28060924,PubMed,10.1371/journal.ppat.1006119,PLoS Pathog. 2017 Jan; 13(1): e1006119,k-satchell@northwestern.edu,The MARTX effector domain region is essential for bacterial dissemination from the intestine.,H E Gavin 2017,2017,2 genes,Gavin-2017-The Effector Domain Region of the V,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9002,PHI:6879,UniProt,Q99XV0,GenBank,AAK34694,,,SF370,emm1,,,,,,,1314,Streptococcus pyogenes,,5448,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,"surface-associated protein, virulence factor",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26468750,PubMed,10.1016/j.chom.2015.09.004,Cell Host Microbe. 2015 Oct 14; 18(4): 471-477,vnizet@ucsd.edu,M1 binds murine cathelicidin and its virulence contribution in a murine model of necrotizing skin infection is largely driven by its ability to neutralize this host defense peptide.,C N LaRock 2015,2015,2 genes,LaRock-2015-Group A Streptococcal M1 Protein S,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9003,PHI:6880,UniProt,P16947,GenBank,AEQ25264,,,Alab49,emm49,,,,,,,1314,Streptococcus pyogenes,471876,NZ131,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,virulence related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26468750,PubMed,10.1016/j.chom.2015.09.004,Cell Host Microbe. 2015 Oct 14; 18(4): 471-477,vnizet@ucsd.edu,M1 binds murine cathelicidin and its virulence contribution in a murine model of necrotizing skin infection is largely driven by its ability to neutralize this host defense peptide.,C N LaRock 2015,2015,2 genes,LaRock-2015-Group A Streptococcal M1 Protein S,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9004,PHI:6879,UniProt,Q99XV0,GenBank,AAK34694,,,SF370,emm1,,,,,,,1314,Streptococcus pyogenes,,5448,infection,rodents,10090,Mus musculus (related: house mouse),129X1(B6)-Camp<tm1Rlg>/Kini,,,skin,"surface-associated protein, virulence factor",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26468750,PubMed,10.1016/j.chom.2015.09.004,Cell Host Microbe. 2015 Oct 14; 18(4): 471-477,vnizet@ucsd.edu,M1 binds murine cathelicidin and its virulence contribution in a murine model of necrotizing skin infection is largely driven by its ability to neutralize this host defense peptide.,C N LaRock 2015,2015,2 genes,LaRock-2015-Group A Streptococcal M1 Protein S,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9005,PHI:6880,UniProt,P16947,GenBank,AEQ25264,,,Alab49,emm49,,,,,,,1314,Streptococcus pyogenes,471876,NZ131,infection,rodents,10090,Mus musculus (related: house mouse),129X1(B6)-Camp<tm1Rlg>/Kini,,,skin,virulence related,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26468750,PubMed,10.1016/j.chom.2015.09.004,Cell Host Microbe. 2015 Oct 14; 18(4): 471-477,vnizet@ucsd.edu,M1 binds murine cathelicidin and its virulence contribution in a murine model of necrotizing skin infection is largely driven by its ability to neutralize this host defense peptide.,C N LaRock 2015,2015,2 genes,LaRock-2015-Group A Streptococcal M1 Protein S,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9006,PHI:6881,UniProt,A0A0A2KRU1,GenBank,KGO39425,,,d1,laeA,,,,,,,27334,Penicillium expansum,,Pe-21,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,global regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27528575,PubMed,10.1111/mpp.12469,Mol Plant Pathol.2016 Aug 16,dovprusk@volcani.agri.gov.il,LaeA affects patulin production in P. expansum by positively regulating the expression ofgenes in the patulin biosynthetic cluster.,D Kumar 2016,2016,1 gene,Kumar-2016-LaeA regulation of secondary metabo,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9007,PHI:6881,UniProt,A0A0A2KRU1,GenBank,KGO39425,,,d1,laeA,,,,,,,27334,Penicillium expansum,1407458,Pe-T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,global regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27528575,PubMed,10.1111/mpp.12469,Mol Plant Pathol.2016 Aug 16,dovprusk@volcani.agri.gov.il,LaeA affects patulin production in P. expansum by positively regulating the expression ofgenes in the patulin biosynthetic cluster.,D Kumar 2016,2016,1 gene,Kumar-2016-LaeA regulation of secondary metabo,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9008,PHI:6882,UniProt,P66796,GenBank,CAD03009,,,CT18,QseB,,,,,,,28901,Salmonella enterica,90370,subsp. enterica serovar Typhi strain GIFU10007,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,two-component system response regulator,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation; gene complementation,,,YVS,28062286,PubMed,10.1016/j.micpath.2017.01.010,Microb Pathog.2017 Mar;104:6-11,870054409@qq.com,Biofilm forming abilities of DqseB and DqseC were both significantly weaker than WT.,Y Ji 2016,2016,2 genes,Ji-2017-QseB mediates biofilm formation and in,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9009,PHI:6883,UniProt,Q8Z3P2,GenBank,CAD03010,,,CT18,QseC,,,,,,,28901,Salmonella enterica,90370,subsp. enterica serovar Typhi strain GIFU10007,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,two-component system sensor histidine kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,28062286,PubMed,10.1016/j.micpath.2017.01.010,Microb Pathog.2017 Mar;104:6-11,870054409@qq.com,Biofilm forming abilities of DqseB and DqseC were both significantly weaker than WT.,Y Ji 2016,2016,2 genes,Ji-2017-QseB mediates biofilm formation and in,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9010,PHI:6884,UniProt,O54286,GenBank,AAQ75792,,,2314,MecA,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,penicillin-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26567511,PubMed,10.1016/j.chom.2015.10.011,Cell Host Microbe.2015 Nov 11;18(5):604-12,david.underhill@csmc.edu,"PGN purified from the low-dose cefoxitin-treated mecA-Tn mutant strongly induced IL-1b secretion from macrophages, while PGN from the untreated mecA-Tn mutant did not.",S Muller 2015,2015,1 gene,Muller-2015-Poorly Cross-Linked Peptidoglycan,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9011,PHI:6885,UniProt,Q63IP8,GenBank,CAH39499,,,K96243,BPSS2021,chromosome 2,,,,,PHI:6885,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,putative decarboxylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27632710,PubMed,10.1111/mmi.13531,Mol Microbiol.2016 Dec;102(6):1004-1019,a.r.brown@exeter.ac.uk,S1PL deficient mutants displayed impaired intracellular replication in murine macrophages (associated withan inability to evade the maturing phagosome) and were significantly attenuated in murine and larval infection models.,R Custodio 2016,2016,4 genes,Custodio-2016-Characterization of secreted sph,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9012,PHI:6886,UniProt,Q63IP4,GenBank,CAH39503,,,K96243,BPSS2025,chromosome 2,,,,,PHI:6884,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,putative decarboxylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27632710,PubMed,10.1111/mmi.13531,Mol Microbiol.2016 Dec;102(6):1004-1019,a.r.brown@exeter.ac.uk,S1PL deficient mutants displayed impaired intracellular replication in murine macrophages (associated withan inability to evade the maturing phagosome) and were significantly attenuated in murine and larval infection models.,R Custodio 2016,2016,4 genes,Custodio-2016-Characterization of secreted sph,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9013,PHI:6886,UniProt,Q63IP4,GenBank,CAH39503,,,K96243,BPSS2025,chromosome 2,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,putative decarboxylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27632710,PubMed,10.1111/mmi.13531,Mol Microbiol.2016 Dec;102(6):1004-1019,a.r.brown@exeter.ac.uk,S1PL deficient mutants displayed impaired intracellular replication in murine macrophages (associated withan inability to evade the maturing phagosome) and were significantly attenuated in murine and larval infection models.,R Custodio 2016,2016,4 genes,Custodio-2016-Characterization of secreted sph,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9014,PHI:6887,UniProt,Q2T8I9,GenBank,ABC33975,,,E264,BTH_II0309,chromosome II,,,,,,57975,Burkholderia thailandensis,271848,E264,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sphingosine-1-phosphate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27632710,PubMed,10.1111/mmi.13531,Mol Microbiol.2016 Dec;102(6):1004-1019,a.r.brown@exeter.ac.uk,S1PL deficient mutants displayed impaired intracellular replication in murine macrophages (associated withan inability to evade the maturing phagosome) and were significantly attenuated in murine and larval infection models.,R Custodio 2016,2016,4 genes,Custodio-2016-Characterization of secreted sph,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9015,PHI:6888,UniProt,Q2T8I7,GenBank,ABC35923,,,E264,BTH_II0311,chromosome II,,,,,,57975,Burkholderia thailandensis,271848,E264,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sphingosine-1-phosphate lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27632710,PubMed,10.1111/mmi.13531,Mol Microbiol.2016 Dec;102(6):1004-1019,a.r.brown@exeter.ac.uk,S1PL deficient mutants displayed impaired intracellular replication in murine macrophages (associated withan inability to evade the maturing phagosome) and were significantly attenuated in murine and larval infection models.,R Custodio 2016,2016,4 genes,Custodio-2016-Characterization of secreted sph,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9016,PHI:6889,UniProt,J9VW44,GenBank,AFR98702,,,H99,cdc50,chromosome 13,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; blood; kidney; liver; spleen; brain,cell division control protein,,,,loss of pathogenicity,,,,,,,,reduced,,no,calcofluor white; sorbitol; caspofungin; SDS; Congo red; caffeine; NaCl; KCl; LiCl,calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911; caspofungin: CHEBI:474180; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653; caffeine: CHEBI:27732; NaCl: CHEBI:26710; KCl: CHEBI:32588; LiCl: CHEBI:48607,,,,,gene mutation; gene complementation,,,YVS,28061020,PubMed,10.1111/cmi.12718,Cell Microbiol.2017 Jan 6,kronstad@interchange.ubc.ca,"Cdc50 mutant in C. neoformans was defective for survival in macrophages, attenuated for virulence in mice and impaired in iron acquisition.",G Hu 2017,2017,1 gene,Hu-2017-A P4 - ATPase subunit of the Cdc50 fam,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9017,PHI:6890,UniProt,P40719,GenBank,AAC76062,,,K-12,QseC,,,,,,,562,Escherichia coli,591946,LF82,infection,rodents,10090,Mus musculus (related: house mouse),BALB/cByJ,,,cecum; colon,sensory histidine kinase in two-component regulatory system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27980034,PubMed,10.1073/pnas.1612836114,Proc Natl Acad Sci U S A.2017 Jan 3;114(1):142-147,wgarrett@hsph.harvard.edu,The absence of qseC leads to down-regulated flagellar expression and motility in vitro and reduced colonization in vivo.,M G Rooks 2017,2017,1 gene,Rooks-2017-QseC inhibition as an antivirulence,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9018,PHI:6891,UniProt,Q4WZA8,GenBank,EAL94057,,,Af293,pksP,chromosome 2,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,conidial pigment polyketide synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,26749442,PubMed,10.1016/j.chom.2015.12.002,CellHost Microbe.2016 Jan 13;19(1):79-90,hamilos@imbb.forth.gr,Host gene alteration data available for Atg5. The attenuated virulence of melanin-deficient A. fumigatus is restored in Atg5-deficient macrophages and in mice upon conditional inactivation of Atg5 in hematopoietic cells.,T Akoumianaki 2016,2016,1 gene,Akoumianaki-2016-Aspergillus Cell Wall Melanin,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9019,PHI:6891,UniProt,Q4WZA8,GenBank,EAL94057,,,Af293,pksP,chromosome 2,,,,,,746128,Aspergillus fumigatus,,ATCC 46645,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),Atg5 flox/flox +vavCre,,,lung,conidial pigment polyketide synthase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,26749442,PubMed,10.1016/j.chom.2015.12.002,CellHost Microbe.2016 Jan 13;19(1):79-90,hamilos@imbb.forth.gr,The attenuated virulence of melanin-deficient A. fumigatus is restored in Atg5-deficient macrophages and in mice upon conditional inactivation of Atg5 in hematopoietic cells.,T Akoumianaki 2016,2016,1 gene,Akoumianaki-2016-Aspergillus Cell Wall Melanin,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9020,PHI:6892,UniProt,A0A0L9JQ40,GenBank,APQ81541,,,RM10961,iscU,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,Fe-S cluster sensor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27704705,PubMed,10.1111/cmi.12680,Cell Microbiol.2017 Apr;19(4),aussel@imm.cnrs.fr,"IscU mutant to invade epithelial cells much less efficiently than the wild-type, whereas the sufBC mutant invasion showed no defect compared to the wild-type, iscR mutant presented an efficiency of entry 1.44-fold higher than the wild-type strain.",A Vergnes 2016,2016,4 genes,Vergnes-2016-The iron-sulfur cluster sensor Is,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9021,PHI:6893,UniProt,A0A0F6B0W4,GenBank,ACY88142,,,14028S,sufB,,,,,,PHI:6893,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,sulfur mobilization,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene mutation,,,YVS,27704705,PubMed,10.1111/cmi.12680,Cell Microbiol.2017 Apr;19(4),aussel@imm.cnrs.fr,"IscU mutant to invade epithelial cells much less efficiently than the wild-type, whereas the sufBC mutant invasion showed no defect compared to the wild-type, iscR mutant presented an efficiency of entry 1.44-fold higher than the wild-type strain.",A Vergnes 2016,2016,4 genes,Vergnes-2016-The iron-sulfur cluster sensor Is,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9022,PHI:6894,UniProt,A0A0M2J080,GenBank,APF09033,,,22495,sufC,,,,,,PHI:6892,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,sulfur mobilization,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene mutation,,,YVS,27704705,PubMed,10.1111/cmi.12680,Cell Microbiol.2017 Apr;19(4),aussel@imm.cnrs.fr,"IscU mutant to invade epithelial cells much less efficiently than the wild-type, whereas the sufBC mutant invasion showed no defect compared to the wild-type, iscR mutant presented an efficiency of entry 1.44-fold higher than the wild-type strain.",A Vergnes 2016,2016,4 genes,Vergnes-2016-The iron-sulfur cluster sensor Is,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9023,PHI:6895,UniProt,Q7CQ10,GenBank,AAL21438,,,LT2; SGSC 1412; ATCC 700720,iscR,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,Fe-S cluster sensor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27704705,PubMed,10.1111/cmi.12680,Cell Microbiol.2017 Apr;19(4),aussel@imm.cnrs.fr,"IscU mutant to invade epithelial cells much less efficiently than the wild-type, whereas the sufBC mutant invasion showed no defect compared to the wild-type, iscR mutant presented an efficiency of entry 1.44-fold higher than the wild-type strain.",A Vergnes 2016,2016,4 genes,Vergnes-2016-The iron-sulfur cluster sensor Is,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9024,PHI:6896,UniProt,A4VXN8,,,,,05ZYH33,1910HK (ssu05 1911),,,,,,,1307,Streptococcus suis,391295,serotype 2 strain 05ZYH33,meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; brain; lung,virulence related two-component system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28093234,PubMed,10.1016/j.micpath.2016.12.026,Microb Pathog.2017 Mar;104:137-145,beiwc@mail.hzau.edu.cn,"1910HK/RR deletion had no effecton S.suis 2 growth, but significantly inhibited the adherence and invasion of S.suis 2 to HEp-2 cells.",F Yuan 2017,2017,2 genes,Yuan-2017-The 1910HK_RR two-component system i,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9025,PHI:6897,UniProt,A4VXN7,,,,,05ZYH33,1910RR (ssu05 1910),,,,,,,1307,Streptococcus suis,391295,serotype 2 strain 05ZYH33,meningitis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,brain; lung,virulence related two-component system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28093234,PubMed,10.1016/j.micpath.2016.12.026,Microb Pathog.2017 Mar;104:137-145,beiwc@mail.hzau.edu.cn,"1910HK/RR deletion had no effecton S.suis 2 growth, but significantly inhibited the adherence and invasion of S.suis 2 to HEp-2 cells.",F Yuan 2017,2017,2 genes,Yuan-2017-The 1910HK_RR two-component system i,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9026,PHI:6898,UniProt,Q4I6S5,GenBank,ESU13277,,,PH-1; NRRL 31084,FgMon1,chromosome 4,,,FgRab7,UniProt: I1RMF2; GenBank: ESU11065,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,spikelet,trafficking protein,,,,reduced virulence,yes,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,sodium dodecyl sulfate (SDS); calcofluor white (CFW),sodium dodecyl sulfate (SDS): CHEBI:8984; calcofluor white (CFW): CHEBI:50011,,,,,gene mutation; gene complementation,,,YVS,26657788,PubMed,10.1038/srep18101,Sci Rep.2015 Dec 10;5:18101,hfzhang@njau.edu.cn,FgMon1 likely acts as a guanine nucleotide exchange factor of FgRab7 and constitutively activated FgRab7 was able to rescue the defects of the Fgmon1 mutant.,Y Li 2015,2015,1 gene,"Li-2015-FgMon1, a guanine nucleotide exchange",BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9027,PHI:6899,UniProt,Q87X57,GenBank,AAO57782,,,DC3000,HopE1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26764598,PubMed,10.1016/j.chom.2015,Cell Host Microbe.2016 Jan 13;19(1):67-78,jalfano2@unl.edu,Host gene alteration data available for MAP65-1 and MAP65-1/MAP65-2 double mutant. Arabidopsis map65-1 mutants were immune deficient and were more susceptible to P. syringae.,M Guo 2016,2016,1 gene,Guo-2016-A Bacterial Effector Co-opts Calmodul,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9028,PHI:6900,UniProt,B8F8P8,GenBank,ACL33700,,,SH0165,vacJ,,,,,,,738,Glaesserella parasuis,,HS49,Glasser's disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen; kidney,virulence related outer membrane lipoprotein,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; KCl,H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,27988234,PubMed,10.1016/j.gene.2016.12.009,Gene.2017 Mar 1;603:42-53,zhengshiminbl@sohu.com,"The vacJ mutant strain caused a decreased survival ratio and exhibited a significant decrease in ability to adhere to and invade PK-15 cell, vacJ mutant showed reduced biofilm formation compared to the wild-type strain. Pathogen formerly called Haemophilus parasuis",L Zhao 2017,2017,1 gene,Zhao-2017-Deletion of the vacJ gene affects th,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9029,PHI:6901,UniProt,G1XLM6,GenBank,XP_011125388,,,ATCC24927,AoHex1,,,,,,,2813651,Orbilia oligospora,756982,CBS 115.81,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,virulence related main protein component of woronin body,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,H2O2; NaCl; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28007213,PubMed,10.1016/j.funbio.2016.08.010,Fungal Biol.2017 Jan;121(1):11-20,kqzhang1@ynu.edu.cn,"Woronin body plays an important role in growth, conidiation, anti-stress, trap formation, and virulence against nematodes in A. oligospora. Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.",L Liang 2017,2017,1 gene,Liang-2017-The Woronin body in the nematophago,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9030,PHI:6902,UniProt,G4N6P7,GenBank,XP_003716183,,,70-15,MoAtg14,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,autophagy-related protein,,,,loss of pathogenicity,,yes,yes,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28067330,PubMed,10.1038/srep40018,Sci Rep.2017 Jan 9;7:40018,fuchenglin@zju.edu.cn,"Moatg14 mutant showed delayed breakdown of glycogen, less lipid bodies, reduced turgor pressure in the appressorium and impaired conidial autophagic cell death.",X H Liu 2017,2017,1 gene,Liu-2017-Autophagy-related protein MoAtg14 is,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9031,PHI:6902,UniProt,G4N6P7,GenBank,XP_003716183,,,70-15,MoAtg14,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,autophagy-related protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28067330,PubMed,10.1038/srep40018,Sci Rep.2017 Jan 9;7:40018,fuchenglin@zju.edu.cn,"Moatg14 mutant showed delayed breakdown of glycogen, less lipid bodies, reduced turgor pressure in the appressorium and impaired conidial autophagic cell death.",X H Liu 2017,2017,1 gene,Liu-2017-Autophagy-related protein MoAtg14 is,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9032,PHI:6903,UniProt,P99075,GenBank,BAB43211,,,N315,FbaA,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,fructose-bisphosphate aldolase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,functional test in host: direct injection,,,YVS,27001537,PubMed,10.1128/IAI.00138-16,Infect Immun.2016 May 24;84(6):1672-81,friedrich.goetz@uni-tuebingen.de,"FbaA showed high cytotoxicity to both MonoMac 6 (MM6) and HaCaT cells, while GAPDH was cytotoxic only for MM6 cells.",P Ebner 2016,2016,2 genes,Ebner-2016-Excreted cytoplasmic proteins contr,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9033,PHI:6904,UniProt,P0A038,GenBank,CAB38645,,,BB,GAPDH,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,glyceraldehyde-3-phosphate dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,functional test in host: direct injection,,,YVS,27001537,PubMed,10.1128/IAI.00138-16,Infect Immun.2016 May 24;84(6):1672-81,friedrich.goetz@uni-tuebingen.de,"FbaA showed high cytotoxicity to both MonoMac 6 (MM6) and HaCaT cells, while GAPDH was cytotoxic only for MM6 cells.",P Ebner 2016,2016,2 genes,Ebner-2016-Excreted cytoplasmic proteins contr,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9034,PHI:6905,,no data found,,,,,,emp A,,,,,,,1352,Enterococcus faecium,749520,TX82,endocarditis,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,heart,pilus subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,26930703,PubMed,10.1128/IAI.01396-15,Infect Immun.2016 Apr 22;84(5):1491-500,bem.asst@uth.tmc.edu,"EmpA and EmpB, but not EmpC, contribute to biofilm and adherence to ECM proteins; however,all the Emp pilins are important for E.faecium to cause infection in the urinary tract.",M C Montealegre 2016,2016,3 genes,Montealegre-2016-Role of the Emp Pilus Subunit,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9035,PHI:6905,,no data found,,,,,,emp A,,,,,,,1352,Enterococcus faecium,749520,TX82,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney; bladder,pilus subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26930703,PubMed,10.1128/IAI.01396-15,Infect Immun.2016 Apr 22;84(5):1491-500,bem.asst@uth.tmc.edu,"EmpA and EmpB, but not EmpC, contribute to biofilm and adherence to ECM proteins; however,all the Emp pilins are important for E.faecium to cause infection in the urinary tract.",M C Montealegre 2016,2016,3 genes,Montealegre-2016-Role of the Emp Pilus Subunit,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9036,PHI:6906,,no data found,,,,,,emp B,,,,,,,1352,Enterococcus faecium,749520,TX82,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney; bladder,pilus subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,26930703,PubMed,10.1128/IAI.01396-15,Infect Immun.2016 Apr 22;84(5):1491-500,bem.asst@uth.tmc.edu,"EmpA and EmpB, but not EmpC, contribute to biofilm and adherence to ECM proteins; however,all the Emp pilins are important for E.faecium to cause infection in the urinary tract.",M C Montealegre 2016,2016,3 genes,Montealegre-2016-Role of the Emp Pilus Subunit,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9037,PHI:6907,,no data found,,,,,,emp C,,,,,,,1352,Enterococcus faecium,749520,TX82,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney; bladder,pilus subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,26930703,PubMed,10.1128/IAI.01396-15,Infect Immun.2016 Apr 22;84(5):1491-500,bem.asst@uth.tmc.edu,"EmpA and EmpB, but not EmpC, contribute to biofilm and adherence to ECM proteins; however,all the Emp pilins are important for E.faecium to cause infection in the urinary tract.",M C Montealegre 2016,2016,3 genes,Montealegre-2016-Role of the Emp Pilus Subunit,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9038,PHI:6905,,no data found,,,,,,emp A,,,,,,PHI:6905; PHI:6906,1352,Enterococcus faecium,749520,TX82,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney; bladder,pilus subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26930703,PubMed,10.1128/IAI.01396-15,Infect Immun.2016 Apr 22;84(5):1491-500,bem.asst@uth.tmc.edu,"EmpA and EmpB, but not EmpC, contribute to biofilm and adherence to ECM proteins; however,all the Emp pilins are important for E.faecium to cause infection in the urinary tract.",M C Montealegre 2016,2016,3 genes,Montealegre-2016-Role of the Emp Pilus Subunit,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9039,PHI:6906,,no data found,,,,,,emp B,,,,,,PHI:6904; PHI:6906,1352,Enterococcus faecium,749520,TX82,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney; bladder,pilus subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,26930703,PubMed,10.1128/IAI.01396-15,Infect Immun.2016 Apr 22;84(5):1491-500,bem.asst@uth.tmc.edu,"EmpA and EmpB, but not EmpC, contribute to biofilm and adherence to ECM proteins; however,all the Emp pilins are important for E.faecium to cause infection in the urinary tract.",M C Montealegre 2016,2016,3 genes,Montealegre-2016-Role of the Emp Pilus Subunit,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9040,PHI:6907,,no data found,,,,,,emp C,,,,,,PHI:6905; PHI:6905,1352,Enterococcus faecium,749520,TX82,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney; bladder,pilus subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,26930703,PubMed,10.1128/IAI.01396-15,Infect Immun.2016 Apr 22;84(5):1491-500,bem.asst@uth.tmc.edu,"EmpA and EmpB, but not EmpC, contribute to biofilm and adherence to ECM proteins; however,all the Emp pilins are important for E.faecium to cause infection in the urinary tract.",M C Montealegre 2016,2016,3 genes,Montealegre-2016-Role of the Emp Pilus Subunit,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9041,PHI:6908,UniProt,Q4WY05,GenBank,EAL92448,,,Af293,atfA,chromosome 3,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,b-ZIP transcription factor,,,,reduced virulence,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9042,PHI:6909,UniProt,Q4WVQ7,GenBank,EAL91319,,,Af293,atfB,chromosome 5,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,b-ZIP transcription factor,,,,reduced virulence,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9043,PHI:6910,UniProt,Q4WR67,GenBank,EAL91065,,,Af293,atfC,chromosome 1,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,b-ZIP transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9044,PHI:6911,UniProt,Q4WLV8,GenBank,EAL89056,,,Af293,atfD,chromosome 6,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,b-ZIP transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9045,PHI:6908,UniProt,Q4WY05,GenBank,EAL92448,,,Af293,atfA,chromosome 3,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,b-ZIP transcription factor,,,,reduced virulence,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9046,PHI:6909,UniProt,Q4WVQ7,GenBank,EAL91319,,,Af293,atfB,chromosome 5,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,b-ZIP transcription factor,,,,reduced virulence,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9047,PHI:6910,UniProt,Q4WR67,GenBank,EAL91065,,,Af293,atfC,chromosome 1,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,b-ZIP transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9048,PHI:6911,UniProt,Q4WLV8,GenBank,EAL89056,,,Af293,atfD,chromosome 6,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,b-ZIP transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9049,PHI:6908,UniProt,Q4WY05,GenBank,EAL92448,,,Af293,atfA,chromosome 3,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,b-ZIP transcription factor,,,,reduced virulence,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9050,PHI:6909,UniProt,Q4WVQ7,GenBank,EAL91319,,,Af293,atfB,chromosome 5,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,b-ZIP transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9051,PHI:6910,UniProt,Q4WR67,GenBank,EAL91065,,,Af293,atfC,chromosome 1,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,b-ZIP transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9052,PHI:6911,UniProt,Q4WLV8,GenBank,EAL89056,,,Af293,atfD,chromosome 6,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,b-ZIP transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9053,PHI:6908,UniProt,Q4WY05,GenBank,EAL92448,,,Af293,atfA,chromosome 3,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,b-ZIP transcription factor,,,,reduced virulence,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9054,PHI:6909,UniProt,Q4WVQ7,GenBank,EAL91319,,,Af293,atfB,chromosome 5,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,b-ZIP transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9055,PHI:6910,UniProt,Q4WR67,GenBank,EAL91065,,,Af293,atfC,chromosome 1,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,b-ZIP transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9056,PHI:6911,UniProt,Q4WLV8,GenBank,EAL89056,,,Af293,atfD,chromosome 6,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,b-ZIP transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; caspofungin; Congo red; fludioxonil; iprodione; menadione; paraquat; t-butyl hydroperoxide; H2O2,"calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909, CAS:36734-19-7; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27706915,PubMed,10.1111/cmi.12681,CellMicrobiol.2017 Apr;19(4),ggoldman@usp.br,"MpkC and SakA activate (and possibly AtfB, -C and -D)as a transcription factor upon different kinds of stresses.",L P Silva 2016,2016,4 genes,Pereira Silva-2016-Genome-wide transcriptome a,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9057,PHI:6912,UniProt,A0A086VCI7,GenBank,AJE56481,,,789,ybtP,,,,,,PHI:6912,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,kidney; bladder,ATP binding cassette protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,26883590,PubMed,10.1128/IAI.01211-15,Infect Immun.2016 Apr 22;84(5):1312-9,jhenderson@DOM.wustl.edu,ybtPQ deletion does not affect growth under iron(III)-Ybt independent conditions.,E I Koh 2016,2016,2 genes,Koh-2016-The yersiniabactin-associated ATP bin,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9058,PHI:6913,UniProt,A0A0E0V727,GenBank,AEQ13038,,,CE10,ybtQ,,,,,,PHI:6911,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeOuJ,,,kidney; bladder,ATP binding cassette protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26883590,PubMed,10.1128/IAI.01211-15,Infect Immun.2016 Apr 22;84(5):1312-9,jhenderson@DOM.wustl.edu,ybtPQ deletion does not affect growth under iron(III)-Ybt independent conditions.,E I Koh 2016,2016,2 genes,Koh-2016-The yersiniabactin-associated ATP bin,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9059,PHI:6914,,no data found,,,,,,PALES_06181,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,probable bacteriophage protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9060,PHI:6915,,no data found,,,,,,PALES_08021,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,DNA replication protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9061,PHI:6916,,no data found,,,,,,PALES_13261,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9062,PHI:6917,,no data found,,,,,,PALES_13451,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,putative uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9063,PHI:6918,,no data found,,,,,,PALES_13521,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,putative portal protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9064,PHI:6919,,no data found,,,,,,PALES_13541,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,putative recombinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9065,PHI:6920,,no data found,,,,,,PALES_25621,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,putative lytic enzyme,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9066,PHI:6921,,no data found,,,,,,PALES_30891,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9067,PHI:6922,,no data found,,,,,,PALES_31041,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,propionate catabolism operon regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9068,PHI:6923,,no data found,,,,,,PALES_41191,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9069,PHI:6924,,no data found,,,,,,PALES_45041,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10117,Rattus rattus (related: black rat),,,,lung,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26268854,PubMed,10.1093/infdis/jiv415,J Infect Dis.2016 Feb 1;213(3):395-402,rclevesq@ibis.ulaval.ca,The 11 signature-tagged mutagenesis mutants having insertions in prophage and genomic island genes showed both diminished virulence and reduced phage production.,A A Lemieux 2015,2015,11 genes,Lemieux-2015-Genes Required for Free Phage Pro,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9070,PHI:6925,,no data found,,,,,,myoB,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,class II myosin,,,,reduced virulence,,,,,,wild type,,wild type,reduced,no,calcofluor white; caspofungin; nikkomycin Z,calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,26953327,PubMed,10.1128/IAI.01190-15,Infect Immun. 2016 May; 84(5): 1556-1564,bill.steinbach@duke.edu,"Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but only myoB is required for conidial viability.",H Renshaw 2016,2016,2 genes,Renshaw-2016-Distinct Roles of Myosins in Aspe,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9071,PHI:6926,UniProt,Q4WTN8,GenBank,XP_754076,,,Af293,myoE,chromosome 5,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,classV myosin,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,calcofluor white; caspofungin; nikkomycin Z,calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,26953327,PubMed,10.1128/IAI.01190-15,Infect Immun. 2016 May; 84(5): 1556-1564,bill.steinbach@duke.edu,"Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but only myoB is required for conidial viability.",H Renshaw 2016,2016,2 genes,Renshaw-2016-Distinct Roles of Myosins in Aspe,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9072,PHI:6925,,no data found,,,,,,myoB,,,,,,PHI:6925,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,class II myosin,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,calcofluor white; caspofungin; nikkomycin Z,calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,26953327,PubMed,10.1128/IAI.01190-15,Infect Immun. 2016 May; 84(5): 1556-1564,bill.steinbach@duke.edu,"Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but only myoB is required for conidial viability.",H Renshaw 2016,2016,2 genes,Renshaw-2016-Distinct Roles of Myosins in Aspe,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9073,PHI:6926,UniProt,Q4WTN8,GenBank,XP_754076,,,Af293,myoE,chromosome 5,,,,,PHI:6924,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,classV myosin,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,calcofluor white; caspofungin; nikkomycin Z,calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,26953327,PubMed,10.1128/IAI.01190-15,Infect Immun. 2016 May; 84(5): 1556-1564,bill.steinbach@duke.edu,"Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but only myoB is required for conidial viability.",H Renshaw 2016,2016,2 genes,Renshaw-2016-Distinct Roles of Myosins in Aspe,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9074,PHI:6925,,no data found,,,,,,myoB,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,class II myosin,,,,reduced virulence,,,,,,wild type,,,,no,calcofluor white; caspofungin; nikkomycin Z,calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,26953327,PubMed,10.1128/IAI.01190-15,Infect Immun. 2016 May; 84(5): 1556-1564,bill.steinbach@duke.edu,"Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but only myoB is required for conidial viability.",H Renshaw 2016,2016,2 genes,Renshaw-2016-Distinct Roles of Myosins in Aspe,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9075,PHI:6926,UniProt,Q4WTN8,GenBank,XP_754076,,,Af293,myoE,chromosome 5,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,classV myosin,,,,reduced virulence,,,,,,reduced,,,,no,calcofluor white; caspofungin; nikkomycin Z,calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,26953327,PubMed,10.1128/IAI.01190-15,Infect Immun. 2016 May; 84(5): 1556-1564,bill.steinbach@duke.edu,"Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but only myoB is required for conidial viability.",H Renshaw 2016,2016,2 genes,Renshaw-2016-Distinct Roles of Myosins in Aspe,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9076,PHI:6925,,no data found,,,,,,myoB,,,,,,PHI:6925,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,class II myosin,,,,reduced virulence,,,,,,reduced,,,,no,calcofluor white; caspofungin; nikkomycin Z,calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,26953327,PubMed,10.1128/IAI.01190-15,Infect Immun. 2016 May; 84(5): 1556-1564,bill.steinbach@duke.edu,"Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but only myoB is required for conidial viability.",H Renshaw 2016,2016,2 genes,Renshaw-2016-Distinct Roles of Myosins in Aspe,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9077,PHI:6926,UniProt,Q4WTN8,GenBank,XP_754076,,,Af293,myoE,chromosome 5,,,,,PHI:6924,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,classV myosin,,,,reduced virulence,,,,,,reduced,,,,no,calcofluor white; caspofungin; nikkomycin Z,calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,26953327,PubMed,10.1128/IAI.01190-15,Infect Immun. 2016 May; 84(5): 1556-1564,bill.steinbach@duke.edu,"Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but only myoB is required for conidial viability.",H Renshaw 2016,2016,2 genes,Renshaw-2016-Distinct Roles of Myosins in Aspe,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9078,PHI:6927,UniProt,G4MVC5,GenBank,EHA54947,,,70-15,MoRAD6,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ubiquitin ligase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9079,PHI:6928,UniProt,G4NE79,GenBank,EHA49408,,,70-15,MoBRE1,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ubiquitin ligase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9080,PHI:6929,UniProt,G4MPW7,GenBank,EHA58055,,,70-15,MoUBR1,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ubiquitin ligase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9081,PHI:6930,UniProt,G4NFA1,GenBank,EHA47283,,,70-15,MoRAD18,chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,DNA repair protein,,,,unaffected pathogenicity,,no,no,,,increased,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9082,PHI:6928,UniProt,G4NE79,GenBank,EHA49408,,,70-15,MoBRE1,chromosome 5,,,,,PHI:6928,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ubiquitin ligase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9083,PHI:6929,UniProt,G4MPW7,GenBank,EHA58055,,,70-15,MoUBR1,chromosome 1,,,,,PHI:6927,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ubiquitin ligase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9084,PHI:6927,UniProt,G4MVC5,GenBank,EHA54947,,,70-15,MoRAD6,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,ubiquitin ligase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9085,PHI:6928,UniProt,G4NE79,GenBank,EHA49408,,,70-15,MoBRE1,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,ubiquitin ligase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9086,PHI:6929,UniProt,G4MPW7,GenBank,EHA58055,,,70-15,MoUBR1,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,ubiquitin ligase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9087,PHI:6930,UniProt,G4NFA1,GenBank,EHA47283,,,70-15,MoRAD18,chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,DNA repair protein,,,,unaffected pathogenicity,,no,no,,,increased,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9088,PHI:6928,UniProt,G4NE79,GenBank,EHA49408,,,70-15,MoBRE1,chromosome 5,,,,,PHI:6928,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,ubiquitin ligase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9089,PHI:6929,UniProt,G4MPW7,GenBank,EHA58055,,,70-15,MoUBR1,chromosome 1,,,,,PHI:6927,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,ubiquitin ligase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27581713,PubMed,10.1111/1462-2920.13515,Environ Microbiol.2016 Nov;18(11):4170-4187,fuchenglin@zju.edu.cn,"Disruption of MoRad6 leads to severe defects in growth, sporulation, conidial germination, appressorium formation and plant infection.",H B Shi 2016,2016,4 genes,Shi-2016-MoRad6-mediated ubiquitination pathwa,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9090,PHI:6931,UniProt,Q9XZW7,GenBank,CAB39969,,,MHOM/IL/81/Friedlin,HASPA1,chromosome 23,,,,,,5664,Leishmania major,,MHOM/JL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lymph node,hydrophilic acylated surface protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28095465,PubMed,10.1371/journal.ppat.1006130,PLoS Pathog.2017 Jan 17;13(1):e1006130,deborah.smith@york.ac.uk,"Metacyclogenesis was stalled in HASP/SHERP mutants in vivo and, although still capable of osmotaxis, these mutants failed to secrete promastigote secretory gel, correlating with a lack of parasite accumulation in the thoracic midgut and failure to colonise the stomodeal valve.",J S Doehl 2017,2017,4 genes,Doehl-2017-Leishmania HASP and SHERP Genes are,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9091,PHI:6932,UniProt,A4I0F6,GenBank,CAM68226,,,JPCM5,HASPA2,chromosome 23,,,,,,5664,Leishmania major,,MHOM/JL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lymph node,hydrophilic acylated surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28095465,PubMed,10.1371/journal.ppat.1006130,PLoS Pathog.2017 Jan 17;13(1):e1006130,deborah.smith@york.ac.uk,"Metacyclogenesis was stalled in HASP/SHERP mutants in vivo and, although still capable of osmotaxis, these mutants failed to secrete promastigote secretory gel, correlating with a lack of parasite accumulation in the thoracic midgut and failure to colonise the stomodeal valve.",J S Doehl 2017,2017,4 genes,Doehl-2017-Leishmania HASP and SHERP Genes are,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9092,PHI:6931,UniProt,Q9XZW7,GenBank,CAB39969,,,MHOM/IL/81/Friedlin,HASPA1,chromosome 23,,,,,,5664,Leishmania major,,MHOM/JL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lymph node,hydrophilic acylated surface protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28095465,PubMed,10.1371/journal.ppat.1006130,PLoS Pathog.2017 Jan 17;13(1):e1006130,deborah.smith@york.ac.uk,"Metacyclogenesis was stalled in HASP/SHERP mutants in vivo and, although still capable of osmotaxis, these mutants failed to secrete promastigote secretory gel, correlating with a lack of parasite accumulation in the thoracic midgut and failure to colonise the stomodeal valve.",J S Doehl 2017,2017,4 genes,Doehl-2017-Leishmania HASP and SHERP Genes are,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9093,PHI:6932,UniProt,A4I0F6,GenBank,CAM68226,,,JPCM5,HASPA2,chromosome 23,,,,,,5664,Leishmania major,,MHOM/JL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lymph node,hydrophilic acylated surface protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28095465,PubMed,10.1371/journal.ppat.1006130,PLoS Pathog.2017 Jan 17;13(1):e1006130,deborah.smith@york.ac.uk,"Metacyclogenesis was stalled in HASP/SHERP mutants in vivo and, although still capable of osmotaxis, these mutants failed to secrete promastigote secretory gel, correlating with a lack of parasite accumulation in the thoracic midgut and failure to colonise the stomodeal valve.",J S Doehl 2017,2017,4 genes,Doehl-2017-Leishmania HASP and SHERP Genes are,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9094,PHI:6931,UniProt,Q9XZW7,GenBank,CAB39969,,,MHOM/IL/81/Friedlin,HASPA1,chromosome 23,,,,,,5664,Leishmania major,,MHOM/JL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lymph node,hydrophilic acylated surface protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28095465,PubMed,10.1371/journal.ppat.1006130,PLoS Pathog.2017 Jan 17;13(1):e1006130,deborah.smith@york.ac.uk,"Metacyclogenesis was stalled in HASP/SHERP mutants in vivo and, although still capable of osmotaxis, these mutants failed to secrete promastigote secretory gel, correlating with a lack of parasite accumulation in the thoracic midgut and failure to colonise the stomodeal valve.",J S Doehl 2017,2017,4 genes,Doehl-2017-Leishmania HASP and SHERP Genes are,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9095,PHI:6932,UniProt,A4I0F6,GenBank,CAM68226,,,JPCM5,HASPA2,chromosome 23,,,,,,5664,Leishmania major,,MHOM/JL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lymph node,hydrophilic acylated surface protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28095465,PubMed,10.1371/journal.ppat.1006130,PLoS Pathog.2017 Jan 17;13(1):e1006130,deborah.smith@york.ac.uk,"Metacyclogenesis was stalled in HASP/SHERP mutants in vivo and, although still capable of osmotaxis, these mutants failed to secrete promastigote secretory gel, correlating with a lack of parasite accumulation in the thoracic midgut and failure to colonise the stomodeal valve.",J S Doehl 2017,2017,4 genes,Doehl-2017-Leishmania HASP and SHERP Genes are,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9096,PHI:6933,UniProt,Q9XTN3,GenBank,CAB39971,,,MHOM/IL/81/Friedlin,SHERP2,chromosome 23,,,,,,5664,Leishmania major,,MHOM/JL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lymph node,small hydrophilic endoplasmic reticulum-associated protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28095465,PubMed,10.1371/journal.ppat.1006130,PLoS Pathog.2017 Jan 17;13(1):e1006130,deborah.smith@york.ac.uk,"Metacyclogenesis was stalled in HASP/SHERP mutants in vivo and, although still capable of osmotaxis, these mutants failed to secrete promastigote secretory gel, correlating with a lack of parasite accumulation in the thoracic midgut and failure to colonise the stomodeal valve.",J S Doehl 2017,2017,4 genes,Doehl-2017-Leishmania HASP and SHERP Genes are,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9097,PHI:6934,UniProt,Q25326,GenBank,CAB39972,,,MHOM/IL/81/Friedlin,HASPB,chromosome 23,,,,,,5664,Leishmania major,,MHOM/JL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lymph node,hydrophilic acylated surface protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28095465,PubMed,10.1371/journal.ppat.1006130,PLoS Pathog.2017 Jan 17;13(1):e1006130,deborah.smith@york.ac.uk,"Metacyclogenesis was stalled in HASP/SHERP mutants in vivo and, although still capable of osmotaxis, these mutants failed to secrete promastigote secretory gel, correlating with a lack of parasite accumulation in the thoracic midgut and failure to colonise the stomodeal valve.",J S Doehl 2017,2017,4 genes,Doehl-2017-Leishmania HASP and SHERP Genes are,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9098,PHI:6935,UniProt,J7HBZ2,GenBank,AFP94095,,,Bb0062,BbpacC,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,pH-response transcription factor,,,,reduced virulence,,,,,,,,,reduced,no,sorbitol; SDS; Congo red; NaCl; KCl; LiCl,sorbitol: CHEBI:30911; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; LiCl: CHEBI:48607,,,,,gene disruption; gene complementation,,,YVS,28083986,PubMed,10.1111/1462-2920.13648,Environ Microbiol.2017 Feb;19(2):788-802,keyhani@ufl.edu,"Despite the impaired ability of B.bassiana to grow at alkaline pH, increased stress susceptibility, and decreased production of oxalate and DPA, the BbpacC mutant strain was only mildly affected in virulence against larvae of either G. mellonella (Lepidoptera) or T. molitor (Coleoptera) in topical bioassays.",Z Luo 2017,2017,1 gene,Luo-2017-The PacC transcription factor regulat,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9099,PHI:6935,UniProt,J7HBZ2,GenBank,AFP94095,,,Bb0062,BbpacC,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva; adult,pH-response transcription factor,,,,reduced virulence,,,,,,,,,,no,sorbitol; SDS; Congo red; NaCl; KCl; LiCl,sorbitol: CHEBI:30911; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; LiCl: CHEBI:48607,,,,,gene disruption; gene complementation,,,YVS,28083986,PubMed,10.1111/1462-2920.13648,Environ Microbiol.2017 Feb;19(2):788-802,keyhani@ufl.edu,"Despite the impaired ability of B.bassiana to grow at alkaline pH, increased stress susceptibility, and decreased production of oxalate and DPA, the BbpacC mutant strain was only mildly affected in virulence against larvae of either G. mellonella (Lepidoptera) or T. molitor (Coleoptera) in topical bioassays.",Z Luo 2017,2017,1 gene,Luo-2017-The PacC transcription factor regulat,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9100,PHI:6936,UniProt,A0A0D2YG10,GenBank,KNB17122,,,4287,fub1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,root,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28093838,PubMed,10.1111/mpp.12536,MolPlantPathol.2017 Jan 17,ge2snlpm@uco.es,"FA contributes to virulence of F. oxysporum on mammals, but is not required for dissemination in the host.",C L Díaz 2017,2017,1 gene,Lopez-Diaz-2017-Fusaric acid contributes to vi,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9101,PHI:6936,UniProt,A0A0D2YG10,GenBank,KNB17122,,,4287,fub1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,rodents,10090,Mus musculus (related: house mouse),OF1,,,kidney; liver; lung,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28093838,PubMed,10.1111/mpp.12536,MolPlantPathol.2017 Jan 17,ge2snlpm@uco.es,"FA contributes to virulence of F. oxysporum on mammals, but is not required for dissemination in the host.",C L Díaz 2017,2017,1 gene,Lopez-Diaz-2017-Fusaric acid contributes to vi,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9102,PHI:6937,UniProt,Q51548,GenBank,CAA80959,,,PAO1,pvdA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,L-ornithine N(5)-monooxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9103,PHI:6937,UniProt,Q51548,GenBank,CAA80959,,,PAO1,pvdA,,,,,,PHI:6937,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,L-ornithine N(5)-monooxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9104,PHI:6938,UniProt,Q9HWG3,GenBank,AE004840_2,,,PAO1,pchD,,,,,,PHI:6936,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,pyochelin biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9105,PHI:6939,UniProt,G3XCV1,GenBank,AAG05814,,,PAO1,pvdS,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9106,PHI:6937,UniProt,Q51548,GenBank,CAA80959,,,PAO1,pvdA,,,,,,PHI:6939,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,L-ornithine N(5)-monooxygenase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9107,PHI:6940,UniProt,Q5DIV2,GenBank,AAX16302,,,PAO1,fpvR,,,,,,PHI:6936,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,Fec operon regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9108,PHI:6941,UniProt,A0A0F6UGK4,GenBank,CRQ13186,,,P32_London_17_VIM_2_10_11,feoB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,ferrous iron transport protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9109,PHI:6942,UniProt,Q51368,GenBank,AAG08916,,,PAO1,tonB1,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,fe3+ transport,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9110,PHI:6942,UniProt,Q51368,GenBank,AAG08916,,,PAO1,tonB1,,,,,,PHI:6940,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,fe3+ transport,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9111,PHI:6941,UniProt,A0A0F6UGK4,GenBank,CRQ13186,,,P32_London_17_VIM_2_10_11,feoB,,,,,,PHI:6941,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,ferrous iron transport protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9112,PHI:6943,UniProt,Q9HYJ7,GenBank,AE004762_2,,,PAO1,hasR,,,,,,PHI:6943,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,heme uptake outer membrane receptor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9113,PHI:6944,UniProt,Q9HV88,GenBank,AE004885_1,,,PAO1,phuR,,,,,,PHI:6942,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,haem/haemoglobin uptake outer membrane receptor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9114,PHI:6938,UniProt,Q9HWG3,GenBank,AE004840_2,,,PAO1,pchD,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,pyochelin biosynthesis protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27271740,PubMed,10.1128/IAI.00098-16,Infect Immun.2016 Jul 21;84(8):2324-35,paolo.visca@uniroma3.it,"Deletion of fpvR in the pvdA background partially restored the lethal phenotype, indicating that pyoverdine contributes to the pathogenesis of P.aeruginosa lung infection by combining iron transport and virulence-inducing capabilities.",F Minandri 2016,2016,8 genes,Minandri-2016-Dissecting the Role of Iron Upta,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9115,PHI:6945,,no data found,GenBank,X52917,,,,rrs,,,,,,,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,16S ribosomal RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27245411,PubMed,10.1128/IAI.00417-16,Infect Immun.2016 Jul 21;84(8):2264-73,tkirikae@ri.ncgm.go.jp,"An rRNA mutation, U1406A, which was generated invitro and confers resistance to kanamycin while highly attenuating M.tuberculosis virulence was described.",S Watanabe 2016,2016,1 gene,Watanabe-2016-A mutation in the decoding regio,BATCH_065B,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9116,PHI:6946,UniProt,A0A1B2LQ61,GenBank,AOA33446,,,WT178,CgAP1,,,,,,,474922,Colletotrichum gloeosporioides,,WT178,anthracnose (mango),eudicots,29780,Mangifera indica (related: mango),,,,fruit,bZip transcription factor,,,,loss of pathogenicity,,,,,,,,,,no,sorbitiol; SDS; Congo red; H2O2,sorbitol: CHEBI:30911; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28219524,PubMed,10.1016/j.micres.2017.01.006,Microbiol Res.2017 Apr;197:39-48,liuzhiqiang80@126.com,"Deletion of CgAP1 in C. gloeosporioides resulted in increasing sensitivity to H2O2, changes in cell wall integrity and loss of pathogenicity.",X Li 2017,2017,1 gene,Li-2017-The function and transcriptome analysi,BATCH_066A,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9117,PHI:6947,UniProt,Q5WTL7,GenBank,CAH16747,,,Lens,sidF,,,,,,PHI:6947,446,Legionella pneumophila,866628,serogroup 1 strain 130b,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28261564,PubMed,10.3389/fcimb.2017.00035,FrontCellInfect Microbiol.2017 Feb 16;7:35,thomas.naderer@monash.edu,"Host gene alteration data available for BCL-RAMBO and BNIP3. In the absence of SidF, L. pneumophila was able to replicate, cause loss of mitochondria membrane potential, kill macrophages, and establish infections in lungs of mice, consistent with this, deletion of BNIP3 and BCL-RAMBO did not affect intracellular L. pneumophila replication, macrophage death rates and in vivo bacterial virulence.",M Speir 2017,2017,2 genes,Speir-2017-Legionella pneumophila Strain 130b,BATCH_066A,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9118,PHI:6948,UniProt,B2C317,GenBank,ABY75869,,,Alcoy 2300/99,flaA,,,,,,PHI:6946,446,Legionella pneumophila,866628,serogroup 1 strain 130b,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28261564,PubMed,10.3389/fcimb.2017.00035,FrontCellInfect Microbiol.2017 Feb 16;7:35,thomas.naderer@monash.edu,"Host gene alteration data available for BCL-RAMBO and BNIP3. In the absence of SidF, L. pneumophila was able to replicate, cause loss of mitochondria membrane potential, kill macrophages, and establish infections in lungs of mice, consistent with this, deletion of BNIP3 and BCL-RAMBO did not affect intracellular L. pneumophila replication, macrophage death rates and in vivo bacterial virulence.",M Speir 2017,2017,2 genes,Speir-2017-Legionella pneumophila Strain 130b,BATCH_066A,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9119,PHI:6948,UniProt,B2C317,GenBank,ABY75869,,,Alcoy 2300/99,flaA,,,,,,,446,Legionella pneumophila,866628,serogroup 1 strain 130b,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28261564,PubMed,10.3389/fcimb.2017.00035,FrontCellInfect Microbiol.2017 Feb 16;7:35,thomas.naderer@monash.edu,"Host gene alteration data available for BCL-RAMBO and BNIP3. In the absence of SidF, L. pneumophila was able to replicate, cause loss of mitochondria membrane potential, kill macrophages, and establish infections in lungs of mice, consistent with this, deletion of BNIP3 and BCL-RAMBO did not affect intracellular L. pneumophila replication, macrophage death rates and in vivo bacterial virulence.",M Speir 2017,2017,2 genes,Speir-2017-Legionella pneumophila Strain 130b,BATCH_066A,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9120,PHI:6949,UniProt,G2XWG3,GenBank,CCD44833,,,T4,BcCLA4,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,effector protein,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation,,,YVS,28164413,PubMed,10.1111/mmi.13642,Mol Microbiol.2017 Feb 6,amirsh@tauex.tau.ac.il,"The bccla4 mutant strains had altered nuclei content, thus connecting the BcRac/BcCla4 module with cell cycle control.",A M Dub 2017,2017,3 genes,Minz-Dub-2017-The Botrytis cinerea PAK kinase,BATCH_066A,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9121,PHI:6950,UniProt,G2YY48,GenBank,CCD56546,,,T4,Bcrac,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,Rac-like GTPase,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation,,,YVS,28164413,PubMed,10.1111/mmi.13642,Mol Microbiol.2017 Feb 6,amirsh@tauex.tau.ac.il,"The bccla4 mutant strains had altered nuclei content, thus connecting the BcRac/BcCla4 module with cell cycle control.",A M Dub 2017,2017,3 genes,Minz-Dub-2017-The Botrytis cinerea PAK kinase,BATCH_066A,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9122,PHI:6951,,no data found,Ensembl Genomes,B0510_5011T1,,,,Bcwee1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. N90598,,,leaf,kinase,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation,,,YVS,28164413,PubMed,10.1111/mmi.13642,Mol Microbiol.2017 Feb 6,amirsh@tauex.tau.ac.il,"The bccla4 mutant strains had altered nuclei content, thus connecting the BcRac/BcCla4 module with cell cycle control.",A M Dub 2017,2017,3 genes,Minz-Dub-2017-The Botrytis cinerea PAK kinase,BATCH_066A,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9123,PHI:6952,UniProt,B8NNC6,GenBank,XP_002381930,,,NRRL3357,AflRmtA,,,,,,,5059,Aspergillus flavus,,PTS (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,histone H4 arginine methyltransferase,,,,unaffected pathogenicity,,,,,,increased,,,,no,calcofluor white; SDS; Congo red; NaCl; KCl; tert-butyl hydroperoxide; H2O2,calcofluor white: CHEBI:50011; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653; ;NaCl: CHEBI:26710; KCl: CHEBI:32588; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,28109854,PubMed,10.1016/j.toxicon.2017.01.013,Toxicon.2017 Mar 1;127:112-121,wshyyl@sina.com,"AflrmtA was found to repress conidiation and up-regulate the AFB1 biosynthesis of A. flavus on peanut and corn seeds and also the activities of protease and lipase, but the activity of amylase was down-regulated.",Y Li 2017,2017,1 gene,Li-2017-Histone Methyltransferase aflrmtA gene,BATCH_066A,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9124,PHI:6952,UniProt,B8NNC6,GenBank,XP_002381930,,,NRRL3357,AflRmtA,,,,,,,5059,Aspergillus flavus,,PTS (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,histone H4 arginine methyltransferase,,,,reduced virulence,,,,,,,,,,no,calcofluor white; SDS; Congo red; NaCl; KCl; tert-butyl hydroperoxide; H2O2,calcofluor white: CHEBI:50011; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653; ;NaCl: CHEBI:26710; KCl: CHEBI:32588; tert-butyl hydroperoxide: CHEBI:64090; H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,28109854,PubMed,10.1016/j.toxicon.2017.01.013,Toxicon.2017 Mar 1;127:112-121,wshyyl@sina.com,"AflrmtA was found to repress conidiation and up-regulate the AFB1 biosynthesis of A. flavus on peanut and corn seeds and also the activities of protease and lipase, but the activity of amylase was down-regulated.",Y Li 2017,2017,1 gene,Li-2017-Histone Methyltransferase aflrmtA gene,BATCH_066A,2017-03-01,MC,,,,,,,,,,,,,
,,Record 9125,PHI:6953,UniProt,A0A0J9WXH4,GenBank,ACD59362,,,PXO99A,gigX1,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,nucleotide sugar transaminase,,,glycan biosynthesis,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28213905,PubMed,10.1111/mpp.12543,Mol Plant Pathol. 2017 Feb 18,hechenyang@caas.cn,"In frame deletion of each gigX gene affected flagellin glycosylation modification, leading to the unglycosylated flagellin of the mutants smaller than the glycosylated one of wildtype.",C Yu 2017,2017,10 genes,Yu-2017-A ten gene-containing genomic island d,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9126,PHI:6954,UniProt,A0A0J9WWZ7,GenBank,ACD59363,,,PXO99A,gigX2,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,acyl carrier protein,,,glycan biosynthesis,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28213905,PubMed,10.1111/mpp.12543,Mol Plant Pathol. 2017 Feb 18,hechenyang@caas.cn,"In frame deletion of each gigX gene affected flagellin glycosylation modification, leading to the unglycosylated flagellin of the mutants smaller than the glycosylated one of wildtype.",C Yu 2017,2017,10 genes,Yu-2017-A ten gene-containing genomic island d,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9127,PHI:6955,UniProt,A0A0J9WWZ8,GenBank,ACD59364,,,PXO99A,gigX3,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,3-oxoacyl-ACP synthase,,,glycan biosynthesis,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28213905,PubMed,10.1111/mpp.12543,Mol Plant Pathol. 2017 Feb 18,hechenyang@caas.cn,"In frame deletion of each gigX gene affected flagellin glycosylation modification, leading to the unglycosylated flagellin of the mutants smaller than the glycosylated one of wildtype.",C Yu 2017,2017,10 genes,Yu-2017-A ten gene-containing genomic island d,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9128,PHI:6956,UniProt,A0A0J9WWZ9,GenBank,ACD59365,,,PXO99A,gigX4,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,3-oxoacyl-ACP reductase,,,glycan biosynthesis,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28213905,PubMed,10.1111/mpp.12543,Mol Plant Pathol. 2017 Feb 18,hechenyang@caas.cn,"In frame deletion of each gigX gene affected flagellin glycosylation modification, leading to the unglycosylated flagellin of the mutants smaller than the glycosylated one of wildtype.",C Yu 2017,2017,10 genes,Yu-2017-A ten gene-containing genomic island d,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9129,PHI:6957,UniProt,A0A0J9WX00,GenBank,ACD59366,,,PXO99A,gigX5,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,dehydrogenase,,,glycan biosynthesis,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28213905,PubMed,10.1111/mpp.12543,Mol Plant Pathol. 2017 Feb 18,hechenyang@caas.cn,"In frame deletion of each gigX gene affected flagellin glycosylation modification, leading to the unglycosylated flagellin of the mutants smaller than the glycosylated one of wildtype.",C Yu 2017,2017,10 genes,Yu-2017-A ten gene-containing genomic island d,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9130,PHI:6958,UniProt,A0A0J9WX01,GenBank,ACD59367,,,PXO99A,gigX6,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,acetyltransferase,,,glycan biosynthesis,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28213905,PubMed,10.1111/mpp.12543,Mol Plant Pathol. 2017 Feb 18,hechenyang@caas.cn,"In frame deletion of each gigX gene affected flagellin glycosylation modification, leading to the unglycosylated flagellin of the mutants smaller than the glycosylated one of wildtype.",C Yu 2017,2017,10 genes,Yu-2017-A ten gene-containing genomic island d,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9131,PHI:6959,UniProt,A0A0J9WXI0,GenBank,ACD59368,,,PXO99A,gigX7,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,ring hydroxylating dioxygenase alpha-subunit,,,glycan biosynthesis,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28213905,PubMed,10.1111/mpp.12543,Mol Plant Pathol. 2017 Feb 18,hechenyang@caas.cn,"In frame deletion of each gigX gene affected flagellin glycosylation modification, leading to the unglycosylated flagellin of the mutants smaller than the glycosylated one of wildtype.",C Yu 2017,2017,10 genes,Yu-2017-A ten gene-containing genomic island d,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9132,PHI:6960,UniProt,A0A0J9WXI1,GenBank,ACD59369,,,PXO99A,gigX8,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,hypothetical protein,,,glycan biosynthesis,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28213905,PubMed,10.1111/mpp.12543,Mol Plant Pathol. 2017 Feb 18,hechenyang@caas.cn,"In frame deletion of each gigX gene affected flagellin glycosylation modification, leading to the unglycosylated flagellin of the mutants smaller than the glycosylated one of wildtype.",C Yu 2017,2017,10 genes,Yu-2017-A ten gene-containing genomic island d,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9133,PHI:6961,UniProt,A0A0J9WXI2,GenBank,ACD59370,,,PXO99A,gigX9,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,methyltransferase,,,glycan biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28213905,PubMed,10.1111/mpp.12543,Mol Plant Pathol. 2017 Feb 18,hechenyang@caas.cn,"In frame deletion of each gigX gene affected flagellin glycosylation modification, leading to the unglycosylated flagellin of the mutants smaller than the glycosylated one of wildtype.",C Yu 2017,2017,10 genes,Yu-2017-A ten gene-containing genomic island d,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9134,PHI:6962,UniProt,A0A0J9WXI3,GenBank,ACD59371,,,PXO99A,gigX10,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,glycosyltransferase,,,glycan biosynthesis,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28213905,PubMed,10.1111/mpp.12543,Mol Plant Pathol. 2017 Feb 18,hechenyang@caas.cn,"In frame deletion of each gigX gene affected flagellin glycosylation modification, leading to the unglycosylated flagellin of the mutants smaller than the glycosylated one of wildtype.",C Yu 2017,2017,10 genes,Yu-2017-A ten gene-containing genomic island d,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9135,PHI:6963,UniProt,Q1XEW2,GenBank,CAJ30496,,,ATCC 46645,cipC,,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,stress response protein,,,,reduced virulence,,,,,,,,wild type,wild type,no,menadione; paraquat ; hydrogen peroxide; sodium nitroprusside; calcium chloride; sodium chloride; magnesium sulfate; calcofluor white; Congo red; sodium dodecyl sulfate; amphotericin B; ketoconazole; itraconazole; fluconazole; terbinafine; anidulafungin; nystatin,"menadione: CHEBI:28869; paraquat: CHEBI:34905; hydrogen peroxide: CHEBI:16240; sodium nitroprusside: CHEBI:29321; calcium chloride: CHEBI:3312; sodium chloride: CHEBI:26710; magnesium sulfate: CHEBI:32599; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; amphotericin B: CHEBI:2682; ketoconazole: CHEBI:47519, CAS:65277-42-1; itraconazole: CHEBI:6076; fluconazole: CHEBI:46081, CAS:86386-73-4; terbinafine: CHEBI:9448, CAS:91161-71-6; anidulafungin: CHEBI:55346; nystatin: CHEBI:7660",,,,,gene deletion: full; gene complementation,,,YVS,28120495,PubMed,10.1111/apm.12648,APMIS.2017 Feb;125(2):141-147,mesfe@fcfrp.usp.br,"Although cipC was not essential, its deletion attenuated A. fumigatus virulence in a low-dose murine infection model.",H M S Canela 2017,2017,1 gene,Canela-2017-cipC is important for Aspergillus,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9136,PHI:6964,UniProt,P56113,GenBank,AAD07235,,,26695,hp0169,,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),GES-1 cell line,,,gastric epithelial cell,putative collagenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,28131950,PubMed,10.1016/j.micpath.2017.01.039,Microb Pathog.2017 Mar;104:225-231,sdliboqing@163.com,Cell apoptosis of H. pylori-infected GES-1 cells was not affected by the deletion of hp0169.,H Zhao 2017,2017,1 gene,Zhao-2017-Functional study of gene hp0169 in H,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9137,PHI:6965,UniProt,A0A0H3NKV1,GenBank,CBW17421,,,SL1344,ssrB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,two-component response regulator,,,mTOR signaling pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28192515,PubMed,10.1371/journal.ppat.1006227,PLoS Pathog.2017 Feb 13;13(2):e1006227,nirmal.robinson@uk-koeln.de,"The degradation of cytosolic Sirt1/LKB1/AMPK complex was not observed with two mutant strains of S. Typhimurium, deltassrB and deltassaV, both compromising the pathogenicity island 2 (SPI2).",R Ganesan 2017,2017,2 genes,Ganesan-2017-Salmonella Typhimurium disrupts S,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9138,PHI:6966,UniProt,D0ZWU0,GenBank,ACY88188,,,14028S,ssaV,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,secretion system apparatus protein,,,mTOR signaling pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28192515,PubMed,10.1371/journal.ppat.1006227,PLoS Pathog.2017 Feb 13;13(2):e1006227,nirmal.robinson@uk-koeln.de,"The degradation of cytosolic Sirt1/LKB1/AMPK complex was not observed with two mutant strains of S. Typhimurium, deltassrB and deltassaV, both compromising the pathogenicity island 2 (SPI2).",R Ganesan 2017,2017,2 genes,Ganesan-2017-Salmonella Typhimurium disrupts S,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9139,PHI:6967,UniProt,Q9RGX0,GenBank,AAF21893,,,LO28,spxA1,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver,redox-responsive transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,hydrogen peroxide; sodium nitroprusside,hydrogen peroxide: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene mutation; gene complementation,,,YVS,28193635,PubMed,10.1128/IAI.00978-16,Infect Immun.2017 Feb 13. pii: IAI.00978-16,reniere@uw.edu,"The data demonstrated that spxA1 was essential for aerobic growth of L. monocytogenes, but that oxygen was not rapidly toxic in the absence of spxA1.",A T Whiteley 2017,2017,2 genes,Whiteley-2017-A redox-responsive transcription,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9140,PHI:6968,UniProt,Q8Y4L1,GenBank,CAD00504,,,EGD-e,spxA2,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver,redox-responsive transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,hydrogen peroxide; sodium nitroprusside,hydrogen peroxide: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene mutation,,,YVS,28193635,PubMed,10.1128/IAI.00978-16,Infect Immun.2017 Feb 13. pii: IAI.00978-16,reniere@uw.edu,"The data demonstrated that spxA1 was essential for aerobic growth of L. monocytogenes, but that oxygen was not rapidly toxic in the absence of spxA1.",A T Whiteley 2017,2017,2 genes,Whiteley-2017-A redox-responsive transcription,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9141,PHI:6967,UniProt,Q9RGX0,GenBank,AAF21893,,,LO28,spxA1,,spxA1::Tn deltaspxA2,,,,PHI:6968,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver,redox-responsive transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,hydrogen peroxide; sodium nitroprusside,hydrogen peroxide: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene mutation,,,YVS,28193635,PubMed,10.1128/IAI.00978-16,Infect Immun.2017 Feb 13. pii: IAI.00978-16,reniere@uw.edu,"The data demonstrated that spxA1 was essential for aerobic growth of L. monocytogenes, but that oxygen was not rapidly toxic in the absence of spxA1.",A T Whiteley 2017,2017,2 genes,Whiteley-2017-A redox-responsive transcription,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9142,PHI:6968,UniProt,Q8Y4L1,GenBank,CAD00504,,,EGD-e,spxA2,,spxA1::Tn deltaspxA2,,,,PHI:6967,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver,redox-responsive transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,hydrogen peroxide; sodium nitroprusside,hydrogen peroxide: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene mutation,,,YVS,28193635,PubMed,10.1128/IAI.00978-16,Infect Immun.2017 Feb 13. pii: IAI.00978-16,reniere@uw.edu,"The data demonstrated that spxA1 was essential for aerobic growth of L. monocytogenes, but that oxygen was not rapidly toxic in the absence of spxA1.",A T Whiteley 2017,2017,2 genes,Whiteley-2017-A redox-responsive transcription,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9143,PHI:6969,UniProt,Q1HA66,GenBank,AB259753,,,,cokel2,,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf; cotyledon,cell morphogenesis protein,,,morphogenesis-related NDR kinase pathway,reduced virulence,,no,no,,,,,,,no,,,,,,,gene mutation,,,YVS,28146587,PubMed,10.1371/journal.ppat.1006189,PLoS Pathog. 2017 Feb 1;13(2):e1006189,y_kubo@kpu.ac.jp,CoPag1delta CoKel2delta was reduced in pathogenicity compared to single mutants.,S Kodama 2017,2017,3 genes,Kodama-2017-The morphogenesis-related NDR kina,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9144,PHI:6970,UniProt,N4VBG2,GenBank,ENH85423,,,MAFF 240422,copag1,,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf; cotyledon,cell morphogenesis protein,,,morphogenesis-related NDR kinase pathway,reduced virulence,,no,no,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28146587,PubMed,10.1371/journal.ppat.1006189,PLoS Pathog. 2017 Feb 1;13(2):e1006189,y_kubo@kpu.ac.jp,CoPag1delta CoKel2delta was reduced in pathogenicity compared to single mutants.,S Kodama 2017,2017,3 genes,Kodama-2017-The morphogenesis-related NDR kina,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9145,PHI:6969,UniProt,Q1HA66,GenBank,AB259753,,,,cokel2,,,,,,PHI:6970,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf; cotyledon,cell morphogenesis protein,,,morphogenesis-related NDR kinase pathway,reduced virulence,,yes,yes,,,,,,aberrant,no,,,,,,,gene mutation,,,YVS,28146587,PubMed,10.1371/journal.ppat.1006189,PLoS Pathog. 2017 Feb 1;13(2):e1006189,y_kubo@kpu.ac.jp,CoPag1delta CoKel2delta was reduced in pathogenicity compared to single mutants.,S Kodama 2017,2017,3 genes,Kodama-2017-The morphogenesis-related NDR kina,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9146,PHI:6970,UniProt,N4VBG2,GenBank,ENH85423,,,MAFF 240422,copag1,,,,,,PHI:6969,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf; cotyledon,cell morphogenesis protein,,,morphogenesis-related NDR kinase pathway,reduced virulence,,yes,yes,,,,,,aberrant,no,,,,,,,gene mutation,,,YVS,28146587,PubMed,10.1371/journal.ppat.1006189,PLoS Pathog. 2017 Feb 1;13(2):e1006189,y_kubo@kpu.ac.jp,CoPag1delta CoKel2delta was reduced in pathogenicity compared to single mutants.,S Kodama 2017,2017,3 genes,Kodama-2017-The morphogenesis-related NDR kina,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9147,PHI:6971,UniProt,N4VA68,GenBank,ENH84264,,,MAFF 240422,cocbk1,,M352A,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf; cotyledon,serine threonine kinase,,,morphogenesis-related NDR kinase pathway,reduced virulence,,yes,yes,,,,,,aberrant,no,,,,,,,gene mutation; gene complementation,,,YVS,28146587,PubMed,10.1371/journal.ppat.1006189,PLoS Pathog. 2017 Feb 1;13(2):e1006189,y_kubo@kpu.ac.jp,CoPag1delta CoKel2delta was reduced in pathogenicity compared to single mutants.,S Kodama 2017,2017,3 genes,Kodama-2017-The morphogenesis-related NDR kina,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9148,PHI:6969,UniProt,Q1HA66,GenBank,AB259753,,,,cokel2,,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,cell morphogenesis protein,,,morphogenesis-related NDR kinase pathway,reduced virulence,,no,no,,,,,,,no,,,,,,,gene mutation,,,YVS,28146587,PubMed,10.1371/journal.ppat.1006189,PLoS Pathog. 2017 Feb 1;13(2):e1006189,y_kubo@kpu.ac.jp,CoPag1delta CoKel2delta was reduced in pathogenicity compared to single mutants.,S Kodama 2017,2017,3 genes,Kodama-2017-The morphogenesis-related NDR kina,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9149,PHI:6970,UniProt,N4VBG2,GenBank,ENH85423,,,MAFF 240422,copag1,,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,cell morphogenesis protein,,,morphogenesis-related NDR kinase pathway,reduced virulence,,no,no,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28146587,PubMed,10.1371/journal.ppat.1006189,PLoS Pathog. 2017 Feb 1;13(2):e1006189,y_kubo@kpu.ac.jp,CoPag1delta CoKel2delta was reduced in pathogenicity compared to single mutants.,S Kodama 2017,2017,3 genes,Kodama-2017-The morphogenesis-related NDR kina,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9150,PHI:6969,UniProt,Q1HA66,GenBank,AB259753,,,,cokel2,,,,,,PHI:6970,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,cell morphogenesis protein,,,morphogenesis-related NDR kinase pathway,reduced virulence,,yes,yes,,,,,,,no,,,,,,,gene mutation,,,YVS,28146587,PubMed,10.1371/journal.ppat.1006189,PLoS Pathog. 2017 Feb 1;13(2):e1006189,y_kubo@kpu.ac.jp,CoPag1delta CoKel2delta was reduced in pathogenicity compared to single mutants.,S Kodama 2017,2017,3 genes,Kodama-2017-The morphogenesis-related NDR kina,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9151,PHI:6970,UniProt,N4VBG2,GenBank,ENH85423,,,MAFF 240422,copag1,,,,,,PHI:6969,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,cell morphogenesis protein,,,morphogenesis-related NDR kinase pathway,reduced virulence,,yes,yes,,,,,,,no,,,,,,,gene mutation,,,YVS,28146587,PubMed,10.1371/journal.ppat.1006189,PLoS Pathog. 2017 Feb 1;13(2):e1006189,y_kubo@kpu.ac.jp,CoPag1delta CoKel2delta was reduced in pathogenicity compared to single mutants.,S Kodama 2017,2017,3 genes,Kodama-2017-The morphogenesis-related NDR kina,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9152,PHI:6972,UniProt,J4UUB6,GenBank,EJP69567,,,ARSEF 2860,TpsA,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,trehalose-6-phosphatesynthase,,,trehalose synthesis,reduced virulence,,,,,,reduced,,reduced,,no,menadione; sodium chloride; Congo red; calcofluor white; hydrogen peroxide; sorbitol,menadione: CHEBI:28869; sodium chloride: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hydrogen peroxide: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,28168316,PubMed,10.1007/s00253-017-8155-2,Appl Microbiol Biotechnol.2017 Feb 6,mgfeng@zju.edu.cn,"Conidial quality indicated by viability, density, intracellular trehalose content, cell wall integrity and hydrophobicity was more impaired in deltatpsA than in deltatpsB and mostly in deltatpsA deltatpsB, which was also most sensitive to nutritional, chemical and environmental stresses and least virulent to Galleria mellonella larvae.",J J Wang 2017,2017,2 genes,Wang-2017-Additive roles of two TPS genes in t,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9153,PHI:6973,UniProt,J4KLP9,GenBank,EJP62584,,,ARSEF 2860,TpsB,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,trehalose-6-phosphatesynthase,,,trehalose synthesis,reduced virulence,,,,,,reduced,,reduced,,no,menadione; sodium chloride; Congo red; calcofluor white; hydrogen peroxide; sorbitol,menadione: CHEBI:28869; sodium chloride: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hydrogen peroxide: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,28168316,PubMed,10.1007/s00253-017-8155-2,Appl Microbiol Biotechnol.2017 Feb 6,mgfeng@zju.edu.cn,"Conidial quality indicated by viability, density, intracellular trehalose content, cell wall integrity and hydrophobicity was more impaired in deltatpsA than in deltatpsB and mostly in deltatpsA deltatpsB, which was also most sensitive to nutritional, chemical and environmental stresses and least virulent to Galleria mellonella larvae.",J J Wang 2017,2017,2 genes,Wang-2017-Additive roles of two TPS genes in t,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9154,PHI:6972,UniProt,J4UUB6,GenBank,EJP69567,,,ARSEF 2860,TpsA,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,trehalose-6-phosphatesynthase,,,trehalose synthesis,reduced virulence,,,,,,reduced,,reduced,,no,menadione; sodium chloride; Congo red; calcofluor white; hydrogen peroxide; sorbitol,menadione: CHEBI:28869; sodium chloride: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hydrogen peroxide: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,28168316,PubMed,10.1007/s00253-017-8155-2,Appl Microbiol Biotechnol.2017 Feb 6,mgfeng@zju.edu.cn,"Conidial quality indicated by viability, density, intracellular trehalose content, cell wall integrity and hydrophobicity was more impaired in deltatpsA than in deltatpsB and mostly in deltatpsA deltatpsB, which was also most sensitive to nutritional, chemical and environmental stresses and least virulent to Galleria mellonella larvae.",J J Wang 2017,2017,2 genes,Wang-2017-Additive roles of two TPS genes in t,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9155,PHI:6973,UniProt,J4KLP9,GenBank,EJP62584,,,ARSEF 2860,TpsB,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,trehalose-6-phosphatesynthase,,,trehalose synthesis,reduced virulence,,,,,,reduced,,reduced,,no,menadione; sodium chloride; Congo red; calcofluor white; hydrogen peroxide; sorbitol,menadione: CHEBI:28869; sodium chloride: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hydrogen peroxide: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,28168316,PubMed,10.1007/s00253-017-8155-2,Appl Microbiol Biotechnol.2017 Feb 6,mgfeng@zju.edu.cn,"Conidial quality indicated by viability, density, intracellular trehalose content, cell wall integrity and hydrophobicity was more impaired in deltatpsA than in deltatpsB and mostly in deltatpsA deltatpsB, which was also most sensitive to nutritional, chemical and environmental stresses and least virulent to Galleria mellonella larvae.",J J Wang 2017,2017,2 genes,Wang-2017-Additive roles of two TPS genes in t,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9156,PHI:6974,UniProt,A0A098DGM6,EMBL,FGRAMPH1_01T10607,,,PH-1; NRRL 31084,gil1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Norm,,,spike,protein kinase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,sodium chloride; Congo red; sodium dodecyl sulfate; calcofluor white,sodium chloride: CHEBI:26710; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene mutation,,,YVS,28212314,PubMed,10.3390/ijms18020424,Int J Mol Sci.2017 Feb 16;18(2). pii: E424,jinrong@purdue.edu,"Deletion of GIL1 resulted in increased hyphal branching and increased tolerance to cell wall and cell membrane stresses, gil1 mutants produced straight, elongated conidia lacking of distinct foot cells and being delayed in germination.",D Yu 2017,2017,1 gene,Yu-2017-A Gin4-Like Protein Kinase GIL1 Involv,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9157,PHI:6974,UniProt,A0A098DGM6,EMBL,FGRAMPH1_01T10607,,,PH-1; NRRL 31084,gil1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Pioneer 2375,,,stem; corn silk,protein kinase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,sodium chloride; Congo red; sodium dodecyl sulfate; calcofluor white,sodium chloride: CHEBI:26710; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene mutation,,,YVS,28212314,PubMed,10.3390/ijms18020424,Int J Mol Sci.2017 Feb 16;18(2). pii: E424,jinrong@purdue.edu,"Deletion of GIL1 resulted in increased hyphal branching and increased tolerance to cell wall and cell membrane stresses, gil1 mutants produced straight, elongated conidia lacking of distinct foot cells and being delayed in germination.",D Yu 2017,2017,1 gene,Yu-2017-A Gin4-Like Protein Kinase GIL1 Involv,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9158,PHI:6975,UniProt,A0A0S1LL44,GenBank,ALL29158,,,,SeCHS-A,,,,,,,176275,Beauveria bassiana,,ANU1,white muscardine,moths,7107,Spodoptera exigua (related: beet armyworm),,,,larva,chitin synthase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28094453,PubMed,10.1002/arch.21371,Arch Insect Biochem Physiol.2017 Feb;94(2),happy2pyj@gmail.com,Suppression of the SeCHS-A gene expression significantly increased 35% of mortality on pupation of S. exigua.,J B Lee 2017,2017,1 gene,Lee-2017-Down-regulation of a chitin synthase,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9159,PHI:6976,UniProt,B0Y2J9,GenBank,EDP52170,,,A1163,Erg4B,,,,,,,746128,Aspergillus fumigatus,,A1160 (Δku80 pyrG),invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,C-24(28) sterol reductase,,,ergosterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,reduced,,no,"D-sorbitol, NaCl, Congo red, calcofluor white, H2O2, menadione, itraconazole, voriconazole, terbinafine, amphotericin B, caspofungin","D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869; itraconazole: CHEBI:6076; voriconazole: CHEBI:10023; terbinafine: CHEBI:9448, CAS:91161-71-6; amphotericin B: CHEBI:2682; caspofungin: CHEBI:474180",,,,,gene deletion: full; gene complementation,,,YVS,27986720,PubMed,10.1128/AEM.02924-16,Appl Environ Microbiol. 2017 Feb 1;83(4). pii: e02924-16,linglu@njnu.edu.cn,deltaerg4A deltaerg4B mutant demonstrated wild-type virulence in a compromised mouse model but displayed remarkable increased susceptibility to antifungal azoles.,N Long 2017,2017,2 genes,Long-2017-Erg4A and Erg4B Are Required for Con,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9160,PHI:6977,UniProt,B0XPT3,GenBank,EDP56047,,,A1163,Erg4A,,,,,,,746128,Aspergillus fumigatus,,A1160 (Δku80 pyrG),invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,C-24(28) sterol reductase,,,ergosterol biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,"D-sorbitol, NaCl, Congo red, calcofluor white, H2O2, menadione, itraconazole, voriconazole, terbinafine, amphotericin B, caspofungin","D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869; itraconazole: CHEBI:6076; voriconazole: CHEBI:10023; terbinafine: CHEBI:9448, CAS:91161-71-6; amphotericin B: CHEBI:2682; caspofungin: CHEBI:474180",,,,,gene deletion: full; gene complementation,,,YVS,27986720,PubMed,10.1128/AEM.02924-16,Appl Environ Microbiol. 2017 Feb 1;83(4). pii: e02924-16,linglu@njnu.edu.cn,deltaerg4A deltaerg4B mutant demonstrated wild-type virulence in a compromised mouse model but displayed remarkable increased susceptibility to antifungal azoles.,N Long 2017,2017,2 genes,Long-2017-Erg4A and Erg4B Are Required for Con,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9161,PHI:6976,UniProt,B0Y2J9,GenBank,EDP52170,,,A1163,Erg4B,,,,,,PHI:6977,746128,Aspergillus fumigatus,,A1160 (Δku80 pyrG),invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,C-24(28) sterol reductase,,,ergosterol biosynthesis pathway,unaffected pathogenicity,,,,,,reduced,,reduced; aberrant,,no,"D-sorbitol, NaCl, Congo red, calcofluor white, H2O2, menadione, itraconazole, voriconazole, terbinafine, amphotericin B, caspofungin","D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869; itraconazole: CHEBI:6076; voriconazole: CHEBI:10023; terbinafine: CHEBI:9448, CAS:91161-71-6; amphotericin B: CHEBI:2682; caspofungin: CHEBI:474180",,,,,gene deletion: full; gene complementation,,,YVS,27986720,PubMed,10.1128/AEM.02924-16,Appl Environ Microbiol. 2017 Feb 1;83(4). pii: e02924-16,linglu@njnu.edu.cn,deltaerg4A deltaerg4B mutant demonstrated wild-type virulence in a compromised mouse model but displayed remarkable increased susceptibility to antifungal azoles.,N Long 2017,2017,2 genes,Long-2017-Erg4A and Erg4B Are Required for Con,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9162,PHI:6977,UniProt,B0XPT3,GenBank,EDP56047,,,A1163,Erg4A,,,,,,PHI:6976,746128,Aspergillus fumigatus,,A1160 (Δku80 pyrG),invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,C-24(28) sterol reductase,,,ergosterol biosynthesis pathway,unaffected pathogenicity,,,,,,reduced,,reduced; aberrant,,no,"D-sorbitol, NaCl, Congo red, calcofluor white, H2O2, menadione, itraconazole, voriconazole, terbinafine, amphotericin B, caspofungin","D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869; itraconazole: CHEBI:6076; voriconazole: CHEBI:10023; terbinafine: CHEBI:9448, CAS:91161-71-6; amphotericin B: CHEBI:2682; caspofungin: CHEBI:474180",,,,,gene deletion: full; gene complementation,,,YVS,27986720,PubMed,10.1128/AEM.02924-16,Appl Environ Microbiol. 2017 Feb 1;83(4). pii: e02924-16,linglu@njnu.edu.cn,deltaerg4A deltaerg4B mutant demonstrated wild-type virulence in a compromised mouse model but displayed remarkable increased susceptibility to antifungal azoles.,N Long 2017,2017,2 genes,Long-2017-Erg4A and Erg4B Are Required for Con,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9163,PHI:6978,UniProt,I1RLP3,EMBL,FGRAMPH1_01T16493,,,CS3005,FgTom1,,,,,,,5518,Fusarium graminearum,1450154,CS3005,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Kennedy,,,root; shoot,tomatinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28109774,PubMed,10.1016/j.fgb.2017.01.007,Fungal Genet Biol. 2017 Mar;100:33-41,Jason.Carere@Canada.ca,deltaTom1 mutants were not different from wild type when grown in culture but showed significant reduction in pathogen virulence in root rot and head blight assays.,J Carere 2017,2017,1 gene,Carere-2017-A tomatinase-like enzyme acts as a,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9164,PHI:6979,UniProt,A0A0F6B6Z9,GenBank,ACY90296,,,14028S,aer,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9165,PHI:6979,UniProt,A0A0F6B6Z9,GenBank,ACY90296,,,14028S,aer,,,,,,PHI:6980,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9166,PHI:6980,UniProt,A0A0F6B845,GenBank,ACY90693,,,14028S,tcp,,,,,,PHI:6979,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9167,PHI:6979,UniProt,A0A0F6B6Z9,GenBank,ACY90296,,,14028S,aer,,,,,,PHI:6980; PHI:6981,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9168,PHI:6980,UniProt,A0A0F6B845,GenBank,ACY90693,,,14028S,tcp,,,,,,PHI:6979; PHI:6981,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9169,PHI:6981,UniProt,A0A0F6BB74,GenBank,ACY91777,,,14028S,tsr,,,,,,PHI:6979; PHI:6980,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9170,PHI:6979,UniProt,A0A0F6B6Z9,GenBank,ACY90296,,,14028S,aer,,,,,,PHI:6980; PHI:6981; PHI:6982,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9171,PHI:6980,UniProt,A0A0F6B845,GenBank,ACY90693,,,14028S,tcp,,,,,,PHI:6979; PHI:6981; PHI:6982,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9172,PHI:6981,UniProt,A0A0F6BB74,GenBank,ACY91777,,,14028S,tsr,,,,,,PHI:6979; PHI:6980; PHI:6982,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9173,PHI:6982,UniProt,A0A0F6B1Q1,GenBank,ACY88437,,,14028S,trg,,,,,,PHI:6979; PHI:6980; PHI:6981,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9174,PHI:6979,UniProt,A0A0F6B6Z9,GenBank,ACY90296,,,14028S,aer,,,,,,PHI:6980; PHI:6981; PHI:6982; PHI:6983,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9175,PHI:6980,UniProt,A0A0F6B845,GenBank,ACY90693,,,14028S,tcp,,,,,,PHI:6979; PHI:6981; PHI:6982; PHI:6983,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9176,PHI:6981,UniProt,A0A0F6BB74,GenBank,ACY91777,,,14028S,tsr,,,,,,PHI:6979; PHI:6980; PHI:6982; PHI:6983,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9177,PHI:6982,UniProt,A0A0F6B1Q1,GenBank,ACY88437,,,14028S,trg,,,,,,PHI:6979; PHI:6980; PHI:6981; PHI:6983,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9178,PHI:6983,UniProt,P02941,GenBank,AAL20835,,,LT2; SGSC 1412; ATCC 700720,cheM,,,,,,PHI:6979; PHI:6980; PHI:6981; PHI:6982,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9179,PHI:6979,UniProt,A0A0F6B6Z9,GenBank,ACY90296,,,14028S,aer,,,,,,PHI:6980; PHI:6981; PHI:6982; PHI:6983; PHI:6984,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9180,PHI:6980,UniProt,A0A0F6B845,GenBank,ACY90693,,,14028S,tcp,,,,,,PHI:6979; PHI:6981; PHI:6982; PHI:6983; PHI:6984,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9181,PHI:6981,UniProt,A0A0F6BB74,GenBank,ACY91777,,,14028S,tsr,,,,,,PHI:6979; PHI:6980; PHI:6982; PHI:6983; PHI:6984,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9182,PHI:6982,UniProt,A0A0F6B1Q1,GenBank,ACY88437,,,14028S,trg,,,,,,PHI:6979; PHI:6980; PHI:6981; PHI:6983; PHI:6984,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9183,PHI:6983,UniProt,P02941,GenBank,AAL20835,,,LT2; SGSC 1412; ATCC 700720,cheM,,,,,,PHI:6979; PHI:6980; PHI:6981; PHI:6982; PHI:6984,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9184,PHI:6984,UniProt,A0A0F6B6Z8,GenBank,ACY90295,,,14028S,mcpC,,,,,,PHI:6979; PHI:6980; PHI:6981; PHI:6982; PHI:6983,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9185,PHI:6979,UniProt,A0A0F6B6Z9,GenBank,ACY90296,,,14028S,aer,,,,,,PHI:6980; PHI:6981; PHI:6982; PHI:6983; PHI:6984; PHI:6985,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9186,PHI:6980,UniProt,A0A0F6B845,GenBank,ACY90693,,,14028S,tcp,,,,,,PHI:6979; PHI:6981; PHI:6982; PHI:6983; PHI:6984; PHI:6985,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9187,PHI:6981,UniProt,A0A0F6BB74,GenBank,ACY91777,,,14028S,tsr,,,,,,PHI:6979; PHI:6980; PHI:6982; PHI:6983; PHI:6984; PHI:6985,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9188,PHI:6982,UniProt,A0A0F6B1Q1,GenBank,ACY88437,,,14028S,trg,,,,,,PHI:6979; PHI:6980; PHI:6981; PHI:6983; PHI:6984; PHI:6985,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9189,PHI:6983,UniProt,P02941,GenBank,AAL20835,,,LT2; SGSC 1412; ATCC 700720,cheM,,,,,,PHI:6979; PHI:6980; PHI:6981; PHI:6982; PHI:6984; PHI:6985,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9190,PHI:6984,UniProt,A0A0F6B6Z8,GenBank,ACY90295,,,14028S,mcpC,,,,,,PHI:6979; PHI:6980; PHI:6981; PHI:6982; PHI:6983; PHI:6985,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9191,PHI:6985,UniProt,A0A0F6B6S3,GenBank,ACY90220,,,14028S,mcpB,,,,,,PHI:6979; PHI:6980; PHI:6981; PHI:6982; PHI:6983; PHI:6984,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28212413,PubMed,10.1371/journal.pone.0172630,PLoS One.2017 Feb 17;12(2):e0172630,GerlachR@rki.de,The successive MCP mutants were functionally tested in a HeLa cell infection model which revealed increased invasion rates for non-chemotactic mutants and strains lacking the MCP CheM (Tar).,S Hoffmann 2017,2017,7 genes,Hoffmann-2017-Scarless deletion of up to seven,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9192,PHI:6986,UniProt,P95830,GenBank,AAL14123,,,CP1200,DnaJ,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,heat shock protein. PI3K and JNK signalling pathway,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28152394,PubMed,10.1016/j.molimm.2017.01.021,Mol Immunol.2017 Mar;83:137-146,wanghongljf@cqmu.edu.cn,"Compared with wild-type parent strain, the abilities of rapid colonization and induction of inflammatory responses of deltadnaJin mouse lungs were significantly impaired.",J Cui 2017,2017,1 gene,Cui-2017-DnaJ (hsp40) of Streptococcus pneumon,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9193,PHI:6986,UniProt,P95830,GenBank,AAL14123,,,CP1200,DnaJ,,,,,,,1313,Streptococcus pneumoniae,171101,R6,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,heat shock protein. PI3K and JNK signalling pathway,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28152394,PubMed,10.1016/j.molimm.2017.01.021,Mol Immunol.2017 Mar;83:137-146,wanghongljf@cqmu.edu.cn,"Compared with wild-type parent strain, the abilities of rapid colonization and induction of inflammatory responses of deltadnaJin mouse lungs were significantly impaired.",J Cui 2017,2017,1 gene,Cui-2017-DnaJ (hsp40) of Streptococcus pneumon,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9194,PHI:6987,UniProt,T0KMX6,GenBank,EQB57057,,,Cg-14,CgareA,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,fruit rot,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,GATA transcription factor,,,,reduced virulence,,,,,,increased,,reduced,reduced,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,28027951,PubMed,10.1016/j.fgb.2016.12.006,Fungal Genet Biol.2017 Feb;99:29-39,dovprusk@agri.gov.il,"Pathogenicityassays indicated that the virulence of deltaareAmutant strains were affected by thenitrogencontent, but not the carbon content, of fruit hosts.",F Bi 2017,2017,1 gene,"Bi-2017-Mutation of AREA affects growth, sporu",BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9195,PHI:6987,UniProt,T0KMX6,GenBank,EQB57057,,,Cg-14,CgareA,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,fruit rot,eudicots,3750,Malus domestica (related: apple),,,,fruit,GATA transcription factor,,,,reduced virulence,,,,,,increased,,reduced,reduced,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,28027951,PubMed,10.1016/j.fgb.2016.12.006,Fungal Genet Biol.2017 Feb;99:29-39,dovprusk@agri.gov.il,"Pathogenicityassays indicated that the virulence of deltaareAmutant strains were affected by thenitrogencontent, but not the carbon content, of fruit hosts.",F Bi 2017,2017,1 gene,"Bi-2017-Mutation of AREA affects growth, sporu",BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9196,PHI:6987,UniProt,T0KMX6,GenBank,EQB57057,,,Cg-14,CgareA,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,fruit rot,eudicots,3758,Prunus domestica (related: plum),,,,fruit,GATA transcription factor,,,,reduced virulence,,,,,,increased,,reduced,reduced,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,28027951,PubMed,10.1016/j.fgb.2016.12.006,Fungal Genet Biol.2017 Feb;99:29-39,dovprusk@agri.gov.il,"Pathogenicityassays indicated that the virulence of deltaareAmutant strains were affected by thenitrogencontent, but not the carbon content, of fruit hosts.",F Bi 2017,2017,1 gene,"Bi-2017-Mutation of AREA affects growth, sporu",BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9197,PHI:6987,UniProt,T0KMX6,GenBank,EQB57057,,,Cg-14,CgareA,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,fruit rot,flowering plants,3435,Persea americana (related: avocado),,,,fruit,GATA transcription factor,,,,unaffected pathogenicity,,,,,,increased,,reduced,reduced,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,28027951,PubMed,10.1016/j.fgb.2016.12.006,Fungal Genet Biol.2017 Feb;99:29-39,dovprusk@agri.gov.il,"Pathogenicityassays indicated that the virulence of deltaareAmutant strains were affected by thenitrogencontent, but not the carbon content, of fruit hosts.",F Bi 2017,2017,1 gene,"Bi-2017-Mutation of AREA affects growth, sporu",BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9198,PHI:6988,UniProt,Q51508,GenBank,CAA57969,,,PAO1,pchA,,,,,,PHI:6989,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,iron siderophore,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9199,PHI:6989,UniProt,Q9HWG3,GenBank,AAG07616,,,PAO1,pchD,,,,,,PHI:6988,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,iron siderophore,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9200,PHI:6990,UniProt,Q9I156,GenBank,AAG05813,,,PAO1,pvdG,,,,,,PHI:6991,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,iron siderophore,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9201,PHI:6991,UniProt,Q9I157,GenBank,AAG05812,,,PAO1,pvdL,,,,,,PHI:6990,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,iron siderophore,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9202,PHI:6992,UniProt,P26993,GenBank,AAA25816,,,388,ExsA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,type III secretion regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9203,PHI:6993,UniProt,O34208,GenBank,AAC16023,,,PA103,ExoU,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,type III secreted toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9204,PHI:6994,UniProt,P26275,GenBank,AAA25704,,,,AlgR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,global regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9205,PHI:6995,UniProt,Q9I4N1,GenBank,AE004540_13,,,PAO1,Flil,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9206,PHI:6996,UniProt,P54292,GenBank,AAC44036,,,PAO1,RhlR,chromosome 1,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,acyl-homoserine-lactone-dependent quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9207,PHI:6997,UniProt,P33883,GenBank,AAA25875,,,PAO1,LasI,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,acyl-homoserine-lactone-dependent quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9208,PHI:6998,UniProt,Q9HWI4,GenBank,AAG07584,,,PAO1,BfiS,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; kidney,sensor kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28246361,PubMed,10.1128/mBio.00140-17,MBio.2017 Feb 28;8(1). pii: e00140-17,bob@hancocklab.com,"Mutants defective in flagella or motility, type III secretion, or siderophore biosynthesis were noninvasive and suppressed dermal necrosis inmice, while a strain with a mutation in thebfiSgene encoding a sensor kinase showed enhanced invasiveness and mortality inmicecompared to controls infected with wild-type strain.",D Pletzer 2017,2017,11 genes,Pletzer-2017-New Mouse Model for Chronic Infec,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9209,PHI:6999,,no data found,,,,,,M949_RS01915,,,,,,,34085,Riemerella anatipestifer,1354240,serotype 1 strain CH3,septicemia anserum exsudativa,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,28166822,PubMed,10.1186/s13567-017-0409-6,Vet Res. 2017 Feb 6;48(1):6,yus@shvri.ac.cn,"RA1067 showed higher susceptibility to complement-dependent killing, more than 360-fold attenuated virulence based on the median lethal dose determination, increased bacterial adhesion and invasion capacities to Vero cells and significantly decreased blood bacterial loads in RA1067 infected ducks, when compared to the CH3.",Y Dou 2017,2017,1 gene,Dou-2017-Disruption of the M949_RS01915 gene c,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9210,PHI:7000,UniProt,Q0UI00,GenBank,EAT83782,,,SN15,elcA,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Emu Rock,,,leaf,polyketide synthase,,,cercosporin pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28251756,PubMed,10.1111/1462-2920.13711,Environ Microbiol.2017 Mar 2,yitheng.chooi@uwa.edu.au,"Wheat seedling infection assays showed that deltaelcA exhibited reduced virulence compared to wild type, while infection by an OE strain overproducing elsinochrome C resulted in larger lesions on leaves.",Y H Chooi 2017,2017,2 genes,Chooi-2017-Functional genomics-guided discover,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9211,PHI:7001,UniProt,Q0UI05,GenBank,EAT83777,,,SN15,elcR,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Emu Rock,,,leaf,transcriptional regulator,,,cercosporin pathway,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28251756,PubMed,10.1111/1462-2920.13711,Environ Microbiol.2017 Mar 2,yitheng.chooi@uwa.edu.au,"Wheat seedling infection assays showed that deltaelcA exhibited reduced virulence compared to wild type, while infection by an OE strain overproducing elsinochrome C resulted in larger lesions on leaves.",Y H Chooi 2017,2017,2 genes,Chooi-2017-Functional genomics-guided discover,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9212,PHI:7002,UniProt,P66860,GenBank,CAD00526,,,EGD-e,smpB,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28202229,PubMed,10.1016/j.ijmm.2017.01.007,Int J Med Microbiol.2017 Apr;307(3):166-173,mobarak.mraheil@mikrobio.med.uni-giessen.de,A smpB knockout significantly decreased the intracellular growth rate of L. monocytogenes during infection of murine macrophages.,M A Mraheilal 2017,2017,1 gene,Mraheil-2017-Requirement of the RNA-binding pr,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9213,PHI:7002,UniProt,P66860,GenBank,CAD00526,,,EGD-e,smpB,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,RNA-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28202229,PubMed,10.1016/j.ijmm.2017.01.007,Int J Med Microbiol.2017 Apr;307(3):166-173,mobarak.mraheil@mikrobio.med.uni-giessen.de,A smpB knockout significantly decreased the intracellular growth rate of L. monocytogenes during infection of murine macrophages.,M A Mraheilal 2017,2017,1 gene,Mraheil-2017-Requirement of the RNA-binding pr,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9214,PHI:7003,UniProt,E3PJ90,GenBank,CBJ02741,,,ETEC H10407,YghJ,,,,,,,562,Escherichia coli,,,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum,secreted metalloprotease and surface associated lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,YVS,28212863,PubMed,10.1016/j.micpath.2017.02.020,Microb Pathog.2017 Apr;105:96-99,apal7364@rediffmail.com,YghJ causes substantial tissue hemorrhage in mouse ileum.,R Tapader 2017,2017,1 gene,"Tapader-2017-YghJ, the secreted metalloproteas",BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9215,PHI:7004,UniProt,A8YPQ5,GenBank,CAP16653,,,Reynolds,CapB2,,,,,,,1280,Staphylococcus aureus,,SA75,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C.NU,,,skin,tyrosine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28239370,PubMed,10.3389/fmicb.2017.00184,Front Microbiol.2017 Feb 10;8:184,wzjxyfy@163.com,"Expression of CapB2 promotes S. aureus virulence in a mouse model of skin infection, and that capB2 gene transcription is regulated negatively by SarA.",D Li 2017,2017,1 gene,Li-2017-capB2 Expression Is Associated with St,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9216,PHI:7005,UniProt,A0A0H2ZPC1,GenBank,ABJ54736,,,D39,EstA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),MF1,,,blood; nasopharynx,tributyrin esterase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,28257499,PubMed,10.1371/journal.ppat.1006263,PLoS Pathog.2017 Mar 3;13(3):e1006263,hy3@le.ac.uk,"Mutation of estA alone or in combination with nanA, or the replacement of its putative serine active site to alanine, reduced the pneumococcal ability to utilise BSM as a sole carbon source, sialic acid release, colonization, and virulence in a mouse model of pneumococcal pneumonia.",H F Kahya 2017,2017,3 genes,Kahya-2017-Deacetylation of sialic acid by est,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9217,PHI:7006,UniProt,P62576,GenBank,AAL00340,,,R6,nanA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),MF1,,,blood; nasopharynx,neuraminidase A,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28257499,PubMed,10.1371/journal.ppat.1006263,PLoS Pathog.2017 Mar 3;13(3):e1006263,hy3@le.ac.uk,"Mutation of estA alone or in combination with nanA, or the replacement of its putative serine active site to alanine, reduced the pneumococcal ability to utilise BSM as a sole carbon source, sialic acid release, colonization, and virulence in a mouse model of pneumococcal pneumonia.",H F Kahya 2017,2017,3 genes,Kahya-2017-Deacetylation of sialic acid by est,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9218,PHI:7005,UniProt,A0A0H2ZPC1,GenBank,ABJ54736,,,D39,EstA,,,,,,PHI:7006,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),MF1,,,blood; nasopharynx,tributyrin esterase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28257499,PubMed,10.1371/journal.ppat.1006263,PLoS Pathog.2017 Mar 3;13(3):e1006263,hy3@le.ac.uk,"Mutation of estA alone or in combination with nanA, or the replacement of its putative serine active site to alanine, reduced the pneumococcal ability to utilise BSM as a sole carbon source, sialic acid release, colonization, and virulence in a mouse model of pneumococcal pneumonia.",H F Kahya 2017,2017,3 genes,Kahya-2017-Deacetylation of sialic acid by est,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9219,PHI:7006,UniProt,P62576,GenBank,AAL00340,,,R6,nanA,,,,,,PHI:7005,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),MF1,,,blood; nasopharynx,neuraminidase A,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28257499,PubMed,10.1371/journal.ppat.1006263,PLoS Pathog.2017 Mar 3;13(3):e1006263,hy3@le.ac.uk,"Mutation of estA alone or in combination with nanA, or the replacement of its putative serine active site to alanine, reduced the pneumococcal ability to utilise BSM as a sole carbon source, sialic acid release, colonization, and virulence in a mouse model of pneumococcal pneumonia.",H F Kahya 2017,2017,3 genes,Kahya-2017-Deacetylation of sialic acid by est,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9220,PHI:7007,UniProt,A0A0H2ZR57,GenBank,ABJ55220,,,D39,Axe,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),MF1,,,blood; nasopharynx,acetyl-xylan esterase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28257499,PubMed,10.1371/journal.ppat.1006263,PLoS Pathog.2017 Mar 3;13(3):e1006263,hy3@le.ac.uk,"Mutation of estA alone or in combination with nanA, or the replacement of its putative serine active site to alanine, reduced the pneumococcal ability to utilise BSM as a sole carbon source, sialic acid release, colonization, and virulence in a mouse model of pneumococcal pneumonia.",H F Kahya 2017,2017,3 genes,Kahya-2017-Deacetylation of sialic acid by est,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9221,PHI:7007,UniProt,A0A0H2ZR57,GenBank,ABJ55220,,,D39,Axe,,,,,,PHI:7006,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),MF1,,,blood; nasopharynx,acetyl-xylan esterase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28257499,PubMed,10.1371/journal.ppat.1006263,PLoS Pathog.2017 Mar 3;13(3):e1006263,hy3@le.ac.uk,"Mutation of estA alone or in combination with nanA, or the replacement of its putative serine active site to alanine, reduced the pneumococcal ability to utilise BSM as a sole carbon source, sialic acid release, colonization, and virulence in a mouse model of pneumococcal pneumonia.",H F Kahya 2017,2017,3 genes,Kahya-2017-Deacetylation of sialic acid by est,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9222,PHI:7006,UniProt,P62576,GenBank,AAL00340,,,R6,nanA,,,,,,PHI:7007,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),MF1,,,blood; nasopharynx,neuraminidase A,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28257499,PubMed,10.1371/journal.ppat.1006263,PLoS Pathog.2017 Mar 3;13(3):e1006263,hy3@le.ac.uk,"Mutation of estA alone or in combination with nanA, or the replacement of its putative serine active site to alanine, reduced the pneumococcal ability to utilise BSM as a sole carbon source, sialic acid release, colonization, and virulence in a mouse model of pneumococcal pneumonia.",H F Kahya 2017,2017,3 genes,Kahya-2017-Deacetylation of sialic acid by est,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9223,PHI:7008,UniProt,D0NRX1,GenBank,EEY63512,,,T30-4,PiLLP,,,,,,,4787,Phytophthora infestans,,MX5-1,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Impala,,,leaf,loricrin-like protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,reduced,no,diphenyleneiodium; H2O2,diphenyleneiodium: CHEBI:77986; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,28232841,PubMed,10.3389/fpls.2017.00142,Front Plant Sci.2017 Feb 9;8:142,ppguo@cau.edu.cn,"PiLLPis important for sexual and asexual reproduction, and is required for oxidative stress tolerance and plant infection.",T Guo 2017,2017,1 gene,Guo-2017-The Loricrin-Like Protein (LLP) of Ph,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9224,PHI:7009,UniProt,Q5AND9,GenBank,AOW28511,,,SC5314,arf2,chromosome 3,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue; kidney; liver; brain,small GTPases of the ARF (ADP-ribosylation factor) family which regulate membrane/protein trafficking,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28192532,PubMed,10.1371/journal.ppat.1006205,PLoS Pathog.2017 Feb 13;13(2):e1006205,mbassila@unice.fr,Arl1 and Arf2 as key regulators of hyphal growth and virulence in C. albicans and identify a unique function of Arl1 in secretion.,H Labbaoui 2017,2017,4 genes,Labbaoui-2017-Role of Arf GTPases in fungal mo,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9225,PHI:7010,UniProt,A0A1D8PJ64,GenBank,AOW28189,,,SC5314,arf3,chromosome 3,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue; kidney; liver; brain,small GTPases of the ARF (ADP-ribosylation factor) family which regulate membrane/protein trafficking,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28192532,PubMed,10.1371/journal.ppat.1006205,PLoS Pathog.2017 Feb 13;13(2):e1006205,mbassila@unice.fr,Arl1 and Arf2 as key regulators of hyphal growth and virulence in C. albicans and identify a unique function of Arl1 in secretion.,H Labbaoui 2017,2017,4 genes,Labbaoui-2017-Role of Arf GTPases in fungal mo,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9226,PHI:7011,UniProt,Q5AMP3,GenBank,AOW28960,,,SC5314,arl1,chromosome 4,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue; kidney; liver; brain,ADP-ribosylation factor-like protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28192532,PubMed,10.1371/journal.ppat.1006205,PLoS Pathog.2017 Feb 13;13(2):e1006205,mbassila@unice.fr,Arl1 and Arf2 as key regulators of hyphal growth and virulence in C. albicans and identify a unique function of Arl1 in secretion.,H Labbaoui 2017,2017,4 genes,Labbaoui-2017-Role of Arf GTPases in fungal mo,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9227,PHI:7012,UniProt,A0A1D8PF23,GenBank,AOW26744,,,SC5314,arl3,chromosome 1,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue; kidney; liver; brain,ADP-ribosylation factor-like protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28192532,PubMed,10.1371/journal.ppat.1006205,PLoS Pathog.2017 Feb 13;13(2):e1006205,mbassila@unice.fr,Arl1 and Arf2 as key regulators of hyphal growth and virulence in C. albicans and identify a unique function of Arl1 in secretion.,H Labbaoui 2017,2017,4 genes,Labbaoui-2017-Role of Arf GTPases in fungal mo,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9228,PHI:7013,,no data found,,,,,,gntR,,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; polymixin B,NaCl: CHEBI:26710; polymixin B: CHEBI:8310,,,,,gene deletion: full; gene complementation,,,YVS,28243986,PubMed,10.1007/s11274-017-2230-9,World J Microbiol Biotechnol. 2017 Mar;33(3):60,allanzhh@sohu.com,Mutation of GntR impairs the cytotoxicity of B. abortus to macrophages.,Z Li 2017,2017,1 gene,Li-2017-Transcriptional regulator GntR of Bruc,BATCH_066B,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9229,PHI:7014,UniProt,Q63KU5,GenBank,CAH38736,,,K96243,glbC,chromosome 2,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; blood,putative peptide synthase/polyketide synthase; proteasome inhibitor,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full; chemical complementation,,,YVS,28323151,PubMed,10.1016/j.micpath.2017.03.015,Microb Pathog. 2017 Mar 18;107:175-180,r.w.titball@exeter.ac.uk,The insertional inactivation or deletion of glbC in this cluster in B.pseudomallei could reduce the ability of the bacterium to survive or grow in murine macrophages or in human neutrophils.,S Wagley 2017,2017,1 gene,Wagley-2017-A proteasome inhibitor produced by,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9230,PHI:7014,UniProt,Q63KU5,GenBank,CAH38736,,,K96243,glbC,chromosome 2,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; blood,putative peptide synthase/polyketide synthase; proteasome inhibitor,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full; chemical complementation,,,YVS,28323151,PubMed,10.1016/j.micpath.2017.03.015,Microb Pathog. 2017 Mar 18;107:175-180,r.w.titball@exeter.ac.uk,The insertional inactivation or deletion of glbC in this cluster in B.pseudomallei could reduce the ability of the bacterium to survive or grow in murine macrophages or in human neutrophils.,S Wagley 2017,2017,1 gene,Wagley-2017-A proteasome inhibitor produced by,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9231,PHI:7015,UniProt,Q88BD8,GenBank,AAO53633,,,DC3000,Crc,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,catabolite repression control protein,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide,hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28384054,PubMed,10.1094/MPMI-09-16-0196-R,Mol Plant Microbe Interact. 2017 Apr 6:MPMI09160196R,Melanie.filiatrault@ars.usda.gov,Deletion of crc increased bacterial swarming motility and biofilmformation.,S Chakravarthy 2017,2017,1 gene,Chakravarthy-2017-Virulence of Pseudomonas syr,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9232,PHI:7015,UniProt,Q88BD8,GenBank,AAO53633,,,DC3000,Crc,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,catabolite repression control protein,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide,hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28384054,PubMed,10.1094/MPMI-09-16-0196-R,Mol Plant Microbe Interact. 2017 Apr 6:MPMI09160196R,Melanie.filiatrault@ars.usda.gov,Deletion of crc increased bacterial swarming motility and biofilmformation.,S Chakravarthy 2017,2017,1 gene,Chakravarthy-2017-Virulence of Pseudomonas syr,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9233,PHI:7016,UniProt,Q9I3I6,GenBank,AE004581_3,,,PAO1,smc,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,condensin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,27528506,PubMed,10.1128/JB.00448-16,J Bacteriol. 2016 Oct 7;198(21):2936-2944,valya@ou.edu,"The inactivation ofSMC induced a state characterized by increased adhesion to surfaces as well as defects incompetitive growth and colony formation. In contrast, MksB-deficient cells were impaired in biofilm formation with no obvious defects during planktonic growth.",H Zhao 2016,2016,2 genes,Zhao-2016-Pseudomonas aeruginosa Condensins Su,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9234,PHI:7016,UniProt,Q9I3I6,GenBank,AE004581_3,,,PAO1,smc,,,,,,PHI:7017,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,condensin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,27528506,PubMed,10.1128/JB.00448-16,J Bacteriol. 2016 Oct 7;198(21):2936-2944,valya@ou.edu,"The inactivation ofSMC induced a state characterized by increased adhesion to surfaces as well as defects incompetitive growth and colony formation. In contrast, MksB-deficient cells were impaired in biofilm formation with no obvious defects during planktonic growth.",H Zhao 2016,2016,2 genes,Zhao-2016-Pseudomonas aeruginosa Condensins Su,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9235,PHI:7017,UniProt,Q9HVB1,GenBank,AE004882_2,,,PAO1,mksB,,,,,,PHI:7016,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,condensin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,27528506,PubMed,10.1128/JB.00448-16,J Bacteriol. 2016 Oct 7;198(21):2936-2944,valya@ou.edu,"The inactivation ofSMC induced a state characterized by increased adhesion to surfaces as well as defects incompetitive growth and colony formation. In contrast, MksB-deficient cells were impaired in biofilm formation with no obvious defects during planktonic growth.",H Zhao 2016,2016,2 genes,Zhao-2016-Pseudomonas aeruginosa Condensins Su,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9236,PHI:7018,UniProt,J9QTF0,GenBank,AFR35806,,,RA-CH-1,B739_1208,,,,,,,34085,Riemerella anatipestifer,1228997,RA-CH-1,septicemia anserum exsudativa,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; brain,putative outer membrane hemin receptor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28284604,PubMed,10.1016/j.vetmic.2017.01.027,Vet Microbiol. 2017 Mar;201:162-169,liumafengra@163.com,R. anatipestifer CH-1DB739_1208 mutants were deficient in iron uptake.,M Wang 2017,2017,1 gene,Wang-2017-Identification of the ferric iron ut,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9237,PHI:7019,UniProt,G4MND3,GenBank,EHA57047,,,70-15,MoMyo5,chromosome 1,,,MoSec4,UniProt: G4N5K7; GenBank: EHA52200,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,actin motor myosin protein,,,,loss of pathogenicity,,no,yes,,,reduced,,reduced,,no,calcoflour white,calcoflour white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,28378891,PubMed,10.1111/mpp.12554,Mol Plant Pathol. 2017 Apr 5,pwang@lsuhsc.edu,"MoMyo5 moved dynamically from the cytoplasm to the hyphal tip where it interacted with MoSec4, a Rab GTPase involved in secretory transport, hyphal growth, and fungal pathogenicity.",W Tang 2017,2017,1 gene,Tang-2017-Disruption of actin motor function d,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9238,PHI:7020,UniProt,P08331,GenBank,AAA97109,,,K12,cpdB,,,,,,,562,Escherichia coli,1196033,APEC-34 O91,colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,lung; liver; spleen,"2′,3′-cyclic phosphodiesterase",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28266315,PubMed,10.1016/j.rvsc.2016.11.010,Res Vet Sci. 2017 Apr;111:21-25,siguo_liu@hvri.ac.cn,"The deletion of the cpdB gene in APEC resulted in reduced growth ability, destruction of cellular integrity and decreased expression of virulence genes (ompA, fur and tnaA).",H Liu 2017,2017,1 gene,Liu-2017-Physiology and pathogenicity of cpdB,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9239,PHI:7021,UniProt,G4N2P7,GenBank,EHA52552,,,70-15,MoJMJ1,chromosome 3,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,putative JmjC-domain-containing histone demethylase,,,,reduced virulence,,yes,,,,reduced,,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation; chemical complementation,,,YVS,28381966,PubMed,10.5423/PPJ.OA.11.2016.0244,Plant Pathol J. 2017 Apr;33(2):193-205,yonglee@snu.ac.kr,"Deletion of MoJMJ1, belonging to JARID group, resulted in defects in vegetative growth, asexual reproduction, appressorium formation as well as invasive growth in the fungus.",A Huh 2017,2017,1 gene,"Huh-2017-MoJMJ1, Encoding a Histone Demethylas",BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9240,PHI:7022,UniProt,E9DVX8,GenBank,EFY92175,,,CQMa 102,beta-tubulin,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,nymph,elementary subunit of microtubules,,,,reduced virulence,,yes,,,,reduced,,reduced; aberrant,wild type,no,calcoflour white,calcoflour white: CHEBI:50011,,,,,gene disruption; gene complementation,,,YVS,28336393,PubMed,10.1016/j.fgb.2017.03.005,Fungal Genet Biol.2017 Mar 20. pii: S1087-1845(17)30053-1,yuxianxia@cqu.edu.cn,"The results indicated that M. acridum, beta-tubulin is not essential for survival but contributes to cellular transport of organelles and cell wall materials, impacting growth, appressorial differentiation, virulence and sporulation. fifth instar nymph",J Zhang 2017,2017,1 gene,Zhang-2017-Contributions of beta-tubulin to ce,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9241,PHI:7023,UniProt,P02931,GenBank,AAA24244,,,,ompF,,,,,,,562,Escherichia coli,,TW-XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; brain; lung; spleen,outer membrane porin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28315387,PubMed,10.1016/j.micpath.2017.02.033,Microb Pathog.2017 Mar 14;107:29-37,yaohch@njau.edu.cn,"The data demonstrated that inactivation of these two porins decreased adhesion, invasion, colonization and proliferation capacities.",H M A Hejair 2017,2017,2 genes,Hejair-2017-Functional role of ompF and ompC p,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9242,PHI:7024,UniProt,P06996,GenBank,AAA24243,,,,ompC,,,,,,,562,Escherichia coli,,TW-XM,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; brain; lung; spleen,outer membrane porin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28315387,PubMed,10.1016/j.micpath.2017.02.033,Microb Pathog.2017 Mar 14;107:29-37,yaohch@njau.edu.cn,"The data demonstrated that inactivation of these two porins decreased adhesion, invasion, colonization and proliferation capacities.",H M A Hejair 2017,2017,2 genes,Hejair-2017-Functional role of ompF and ompC p,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9243,PHI:7023,UniProt,P02931,GenBank,AAA24244,,,,ompF,,,,,,,562,Escherichia coli,,TW-XM,meningitis,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; lung; spleen,outer membrane porin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28315387,PubMed,10.1016/j.micpath.2017.02.033,Microb Pathog.2017 Mar 14;107:29-37,yaohch@njau.edu.cn,"The data demonstrated that inactivation of these two porins decreased adhesion, invasion, colonization and proliferation capacities.",H M A Hejair 2017,2017,2 genes,Hejair-2017-Functional role of ompF and ompC p,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9244,PHI:7024,UniProt,P06996,GenBank,AAA24243,,,,ompC,,,,,,,562,Escherichia coli,,TW-XM,meningitis,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; lung; spleen,outer membrane porin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28315387,PubMed,10.1016/j.micpath.2017.02.033,Microb Pathog.2017 Mar 14;107:29-37,yaohch@njau.edu.cn,"The data demonstrated that inactivation of these two porins decreased adhesion, invasion, colonization and proliferation capacities.",H M A Hejair 2017,2017,2 genes,Hejair-2017-Functional role of ompF and ompC p,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9245,PHI:7025,UniProt,A0A0E0SA40,GenBank,CEF83303,,,PH-1,FgRav2,chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Iride,,,seedling; kernel,"hypothetical protein of 318 amino acids, containing a ROGDI like leucine zipper domain known to have a regulatory role",,,trichothecene type B biosynthesis,loss of pathogenicity,,,,,,,,reduced,reduced,no,sorbitol; SDS; NaCl; potassium persulfate; tebuconazole,sorbitol: CHEBI:30911; SDS: CHEBI:8984; NaCl: CHEBI:26710; potassium persulfate: CAS:7727-21-1; tebuconazole: CHEBI:81781,,,,,gene deletion: full; gene complementation,,,YVS,28322011,PubMed,10.1111/mpp.12551,Mol Plant Pathol.2017 Mar 21,matias.pasquali@unimi.it,"Deletion of FcRav2 or its orthologous gene in F. graminearum highlighted its ability to influence a number of functions including virulence, trichothecene type B biosynthesis, resistance to azoles and resistance to osmotic and oxidative stress.",F Spanu 2017,2017,2 genes,"Spanu-2017-FcRav2, A Gene with rogdi domain in",BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9246,PHI:7026,,no data found,GenBank,FCUL_11566.1,,,UK99,FcRav2,,,,,,,5516,Fusarium culmorum,,UK99,Fusarium head blight; Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Iride,,,seedling; kernel,"hypothetical protein of 318 amino acids, containing a ROGDI like leucine zipper domain known to have a regulatory role",,,trichothecene type B biosynthesis,loss of pathogenicity,,,,,,,,reduced,reduced,no,sorbitol; SDS; NaCl; potassium persulfate; tebuconazole,sorbitol: CHEBI:30911; SDS: CHEBI:8984; NaCl: CHEBI:26710; potassium persulfate: CAS:7727-21-1; tebuconazole: CHEBI:81781,,,,,gene deletion: full; gene complementation,,,YVS,28322011,PubMed,10.1111/mpp.12551,Mol Plant Pathol.2017 Mar 21,matias.pasquali@unimi.it,"Deletion of FcRav2 or its orthologous gene in F. graminearum highlighted its ability to influence a number of functions including virulence, trichothecene type B biosynthesis, resistance to azoles and resistance to osmotic and oxidative stress.",F Spanu 2017,2017,2 genes,"Spanu-2017-FcRav2, A Gene with rogdi domain in",BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9247,PHI:7027,UniProt,J7KLB9,GenBank,AFQ98267,,,ZY458,vapE,,,,,,,1307,Streptococcus suis,,serotype 2 strain ZY458,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; liver; lung; spleen; kidney,virulence-associated protein E,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,26821177,PubMed,10.3892/mmr.2016.4818,Mol Med Rep.2016 Mar;13(3):2871-7,fengsz@hotmail.com,,X Ji 2016,2016,1 gene,Ji-2016-A novel virulence-associated protein,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9248,PHI:7028,UniProt,P25535,GenBank,BAA14327,,,K12 CA274,ubiI,,,,,,,562,Escherichia coli,364106,UTI89,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,urinary bladder,aerobic ubiquinone-8 synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27161114,PubMed,10.1128/JB.00030-16,J Bacteriol.2016 Sep 9;198(19):2662-72,maria.hadjifrangiskou@vanderbilt.edu,"The data suggested that during acute bladder infection, there is enough oxygen to induce aerobic respiration within UPEC, and impairment of aerobic ubiquinone synthesis leads to reduced virulence in a murine model of infection.",K A Floyd 2016,2016,1 gene,Floyd-2016-_The UbiI (VisC) aerobic ubiquinone,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9249,PHI:7029,,no data found,JGI,Pc504276,,,,PcLRR-RK1,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,leucine Rich repeat-receptor kinase,,,,reduced virulence,,,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28285663,PubMed,10.1016/j.micres.2017.01.008,Microbiol Res. 2017 May;198:8-15,ddou@njau.edu.cn,"Silencing of the PcLRR-RK1 gene affected the cyst germination and penetration of germ tube into the host tissues, and led to the reduced virulence of P. capsici.",A Safdar 2017,2017,1 gene,Safdar-2017-An LRR receptor kinase regulates g,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9250,PHI:7029,,no data found,GenBank,Pc504276,,,,PcLRR-RK1,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia,,,leaf,leucine Rich repeat-receptor kinase,,,,reduced virulence,,,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28285663,PubMed,10.1016/j.micres.2017.01.008,Microbiol Res. 2017 May;198:8-15,ddou@njau.edu.cn,"Silencing of the PcLRR-RK1 gene affected the cyst germination and penetration of germ tube into the host tissues, and led to the reduced virulence of P. capsici.",A Safdar 2017,2017,1 gene,Safdar-2017-An LRR receptor kinase regulates g,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9251,PHI:7030,UniProt,I1RG19,GenBank,ESU08133,,,PH-1; NRRL 31084,FgLAI12,chromosome 1,,,,,,5518,Fusarium graminearum,,DAOM 180378,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,linoleic acid isomerase,,,,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28387243,PubMed,10.1038/srep46129,Sci Rep. 2017 Apr 7;7:46129,pengfeiqi@hotmail.com,"Disruption of FgLAI12 in F. graminearum resulted in decreased accumulation of cis-9, trans-11 CLA, enhanced sensitivity to salicylic acid, and increased accumulation of linoleic acid and salicylic acid in wheat spikes during infection.",Y Z Zhang 2017,2017,1 gene,Zhang-2017-Linoleic acid isomerase gene FgLAI1,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9252,PHI:7031,UniProt,Q887P8,GenBank,AAM23310,,,DC3000,algD,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,GDP mannose dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27325679,PubMed,10.1128/JB.00276-16,J Bacteriol. 2016 Aug 11;198(17):2330-44,Bryan.Swingle@ars.usda.gov,Leaves infected with the algU mucAB mutant showed reduced chlorosis and fewer necrotic spots and this mutant grew to a lower density in leaves.,E Markel 2016,2016,4 genes,Markel-2016-AlgU controls expression of virule,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9253,PHI:7032,UniProt,F3GTC1,GenBank,EGH50324,,,Cit 7,algU,,,,,,PHI:7033; PHI:7034,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,extracytoplasmic function(ECF) sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27325679,PubMed,10.1128/JB.00276-16,J Bacteriol. 2016 Aug 11;198(17):2330-44,Bryan.Swingle@ars.usda.gov,Leaves infected with the algU mucAB mutant showed reduced chlorosis and fewer necrotic spots and this mutant grew to a lower density in leaves.,E Markel 2016,2016,4 genes,Markel-2016-AlgU controls expression of virule,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9254,PHI:7033,UniProt,Q87XF5,GenBank,AAO57679,,,DC3000,mucA,,,,,,PHI:7032; PHI:7034,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,anti-sigmafactor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27325679,PubMed,10.1128/JB.00276-16,J Bacteriol. 2016 Aug 11;198(17):2330-44,Bryan.Swingle@ars.usda.gov,Leaves infected with the algU mucAB mutant showed reduced chlorosis and fewer necrotic spots and this mutant grew to a lower density in leaves.,E Markel 2016,2016,4 genes,Markel-2016-AlgU controls expression of virule,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9255,PHI:7034,UniProt,Q87XF6,GenBank,AAO57678,,,DC3000,mucB,,,,,,PHI:7032; PHI:7033,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,anti-sigmafactor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27325679,PubMed,10.1128/JB.00276-16,J Bacteriol. 2016 Aug 11;198(17):2330-44,Bryan.Swingle@ars.usda.gov,Leaves infected with the algU mucAB mutant showed reduced chlorosis and fewer necrotic spots and this mutant grew to a lower density in leaves.,E Markel 2016,2016,4 genes,Markel-2016-AlgU controls expression of virule,BATCH_067A,2017-04-01,MC,,,,,,,,,,,,,
,,Record 9256,PHI:7035,UniProt,J5JB66,GenBank,EJP63368,,,ARSEF 2860,Pmt1,,"Mpmt1K88R, Mpmt1K482R",,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,O-mannosyltransferase,,,,reduced virulence,,,,,,reduced,,wild type,,no,H2O2; Congo red; NaCl,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710,,,,,gene mutation: characterised; gene complementation,,,YVS,28295016,PubMed,10.1038/srep44360,Sci Rep. 2017 Mar 15;7:44360,mgfeng@zju.edu.cn,"The results indicated the essentiality of either K88 or K482 for a significant role of Pmt1 in the asexual development, host infection and some stress responses, and also indicated the significance of K360 for the function of Pmt4 in B. bassiana.",Z K Wang 2017,2017,2 genes,Wang-2017-Global Insight into Lysine Acetylati,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9257,PHI:7035,UniProt,J5JB66,GenBank,EJP63368,,,ARSEF 2860,Pmt1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,O-mannosyltransferase,,,,reduced virulence,,,,,,reduced,,,,no,H2O2; Congo red; NaCl,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,YVS,28295016,PubMed,10.1038/srep44360,Sci Rep. 2017 Mar 15;7:44360,mgfeng@zju.edu.cn,"The results indicated the essentiality of either K88 or K482 for a significant role of Pmt1 in the asexual development, host infection and some stress responses, and also indicated the significance of K360 for the function of Pmt4 in B. bassiana.",Z K Wang 2017,2017,2 genes,Wang-2017-Global Insight into Lysine Acetylati,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9258,PHI:7036,UniProt,J5K1X2,GenBank,EJP70423,,,ARSEF 2860,Pmt4,,Mpmt4K360R,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,O-mannosyltransferase,,,,increased virulence (hypervirulence),,,,,,wild type,,increased,,no,H2O2; Congo red; NaCl,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710,,,,,gene mutation: characterised; gene complementation,,,YVS,28295016,PubMed,10.1038/srep44360,Sci Rep. 2017 Mar 15;7:44360,mgfeng@zju.edu.cn,"The results indicated the essentiality of either K88 or K482 for a significant role of Pmt1 in the asexual development, host infection and some stress responses, and also indicated the significance of K360 for the function of Pmt4 in B. bassiana.",Z K Wang 2017,2017,2 genes,Wang-2017-Global Insight into Lysine Acetylati,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9259,PHI:7036,UniProt,J5K1X2,GenBank,EJP70423,,,ARSEF 2860,Pmt4,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,O-mannosyltransferase,,,,reduced virulence,,,,,,reduced,,,,no,H2O2; Congo red; NaCl,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,YVS,28295016,PubMed,10.1038/srep44360,Sci Rep. 2017 Mar 15;7:44360,mgfeng@zju.edu.cn,"The results indicated the essentiality of either K88 or K482 for a significant role of Pmt1 in the asexual development, host infection and some stress responses, and also indicated the significance of K360 for the function of Pmt4 in B. bassiana.",Z K Wang 2017,2017,2 genes,Wang-2017-Global Insight into Lysine Acetylati,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9260,PHI:7037,UniProt,U2UML5,GenBank,ERL19273,,,GA06023,SpxA1,,,,,,,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9261,PHI:7038,UniProt,U2W9V3,GenBank,ERL21461,,,GA06023,SpxA2,,,,,,,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9262,PHI:7037,UniProt,U2UML5,GenBank,ERL19273,,,GA06023,SpxA1,,,,,,PHI:7038,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9263,PHI:7038,UniProt,U2W9V3,GenBank,ERL21461,,,GA06023,SpxA2,,,,,,PHI:7037,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9264,PHI:7039,UniProt,A0A0G2UVN6,GenBank,AKI35490,,,NGAS743,ClpX,,,,,,,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,ATP-dependent Clp protease ATP-binding subunit,,,,reduced virulence,,,,,,,,increased,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9265,PHI:7039,UniProt,A0A0G2UVN6,GenBank,AKI35490,,,NGAS743,ClpX,,,,,,PHI:7037,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,ATP-dependent Clp protease ATP-binding subunit,,,,reduced virulence,,,,,,,,increased,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9266,PHI:7037,UniProt,U2UML5,GenBank,ERL19273,,,GA06023,SpxA1,,,,,,PHI:7039,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9267,PHI:7039,UniProt,A0A0G2UVN6,GenBank,AKI35490,,,NGAS743,ClpX,,,,,,PHI:7038,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,ATP-dependent Clp protease ATP-binding subunit,,,,unaffected pathogenicity,,,,,,,,increased,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9268,PHI:7038,UniProt,U2W9V3,GenBank,ERL21461,,,GA06023,SpxA2,,,,,,PHI:7039,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9269,PHI:7040,UniProt,P0C0J0,GenBank,AAA26978,,,86858,SpeB,,,,,,,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,cysteine protease,,,,reduced virulence,,,,,,,,reduced,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9270,PHI:7040,UniProt,P0C0J0,GenBank,AAA26978,,,86858,SpeB,,,,,,PHI:7038,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,cysteine protease,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9271,PHI:7038,UniProt,U2W9V3,GenBank,ERL21461,,,GA06023,SpxA2,,,,,,PHI:7040,1314,Streptococcus pyogenes,1336746,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,skin,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"1,1'-azobis(N,N-dimethylformamide); paraquat","1,1'-azobis(N,N-dimethylformamide): CHEBI:48958; paraquat: CHEBI:34905",,,,,gene mutation,,,YVS,28351920,PubMed,10.1128/mBio.00288-17,MBio.2017 Mar 28;8(2). pii: e00288-17,caparon@wusm.wustl.edu,"SpxA1- mutants were defective for growth under aerobic conditions, while SpxA2- mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses.",G C Port 2017,2017,4 genes,Port-2017-SpxA1 and SpxA2 Act Coordinately To,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9272,PHI:7041,,no data found,,,,,EDL933,T6SS,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,type VI secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,28288207,PubMed,10.1371/journal.ppat.1006246,PLoS Pathog. 2017 Mar 13;13(3):e1006246,wwj1210@126.com,The deletion mutant of T6SS (z0243 to z0275) was constructed by replacing the 37 kb T6SS gene cluster with chloramphenicol resistance cassette. Primary peritoneal macrophage cell tissue.,B Wan 2017,2017,2 genes,Wan-2017-Type VI secretion system contributes,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9273,PHI:7042,UniProt,Q8XDQ1,GenBank,BAB35075,,,EDL933,katN,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,28288207,PubMed,10.1371/journal.ppat.1006246,PLoS Pathog. 2017 Mar 13;13(3):e1006246,wwj1210@126.com,"The deletion mutant of T6SS was attenuated in virulence compared with the wild type strain, while the deletion mutant of katN had comparable virulence to the wild type strain. Primary peritoneal macrophage cell tissue.",B Wan 2017,2017,2 genes,Wan-2017-Type VI secretion system contributes,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9274,PHI:7043,UniProt,Q99Z27,GenBank,AAK34240,,,SF370,PmtA,,,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,P1B4-type ATPase that functions as an Fe(II) exporter,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28348051,PubMed,10.1128/IAI.00091-17,Infect Immun.2017 Mar 27. pii: IAI.00091-17,mkumaraswami@houstonmethodist.org,"Using two mouse models of invasive infection, it was demonstrated that iron efflux by PmtA is critical for bacterial survival during infection and GAS virulence.",A R VanderWal 2017,2017,1 gene,VanderWal-2017-Iron efflux by PmtA is critical,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9275,PHI:7043,UniProt,Q99Z27,GenBank,AAK34240,,,SF370,PmtA,,,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,skin lesion,rodents,10090,Mus musculus (related: house mouse),Crl:SKH1-Hr<hr>,,,muscle,P1B4-type ATPase that functions as an Fe(II) exporter,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28348051,PubMed,10.1128/IAI.00091-17,Infect Immun.2017 Mar 27. pii: IAI.00091-17,mkumaraswami@houstonmethodist.org,"Using two mouse models of invasive infection, it was demonstrated that iron efflux by PmtA is critical for bacterial survival during infection and GAS virulence.",A R VanderWal 2017,2017,1 gene,VanderWal-2017-Iron efflux by PmtA is critical,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9276,PHI:7044,UniProt,P9WIQ7,GenBank,AAA96136,,,Mt103,RvErp,,,,Rv2212,UniProt: P9WMU7; GenBank: CCP44989,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,exported repetitive protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; heterologous expression,,,YVS,27481930,PubMed,10.1128/JB.00120-16,J Bacteriol.2016 Sep 22;198(20):2841-52,chash71@yahoo.com,Increased cAMP production due to the interaction of RvErp with Rv2212 enhances the survival of M.smegmatis within macrophages.,A A Ganaie 2016,2016,2 genes,Ganaie-2016-Interaction of Erp Protein of Myco,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9277,PHI:7045,UniProt,P9WMU7,GenBank,CCP44989,,,H37Rv,Rv2212,,,,RvErp,UniProt: P9WIQ7; GenBank: AAA96136,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,adenylylcyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,heterologous expression,,,YVS,27481930,PubMed,10.1128/JB.00120-16,J Bacteriol.2016 Sep 22;198(20):2841-52,chash71@yahoo.com,Increased cAMP production due to the interaction of RvErp with Rv2212 enhances the survival of M.smegmatis within macrophages.,A A Ganaie 2016,2016,2 genes,Ganaie-2016-Interaction of Erp Protein of Myco,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9278,PHI:7045,UniProt,P9WMU7,GenBank,CCP44989,,,H37Rv,Rv2212,,,,RvErp,UniProt: P9WIQ7; GenBank: AAA96136,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,adenylylcyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; heterologous expression,,,YVS,27481930,PubMed,10.1128/JB.00120-16,J Bacteriol.2016 Sep 22;198(20):2841-52,chash71@yahoo.com,Increased cAMP production due to the interaction of RvErp with Rv2212 enhances the survival of M.smegmatis within macrophages.,A A Ganaie 2016,2016,2 genes,Ganaie-2016-Interaction of Erp Protein of Myco,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9279,PHI:7044,UniProt,P9WIQ7,GenBank,AAA96136,,,Mt103,RvErp,,,,Rv2212,UniProt: P9WMU7; GenBank: CCP44989,PHI:7045,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,exported repetitive protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; heterologous expression,,,YVS,27481930,PubMed,10.1128/JB.00120-16,J Bacteriol.2016 Sep 22;198(20):2841-52,chash71@yahoo.com,Increased cAMP production due to the interaction of RvErp with Rv2212 enhances the survival of M.smegmatis within macrophages.,A A Ganaie 2016,2016,2 genes,Ganaie-2016-Interaction of Erp Protein of Myco,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9280,PHI:7045,UniProt,P9WMU7,GenBank,CCP44989,,,H37Rv,Rv2212,,,,RvErp,UniProt: P9WIQ7; GenBank: AAA96136,PHI:7044,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,adenylylcyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,heterologous expression,,,YVS,27481930,PubMed,10.1128/JB.00120-16,J Bacteriol.2016 Sep 22;198(20):2841-52,chash71@yahoo.com,Increased cAMP production due to the interaction of RvErp with Rv2212 enhances the survival of M.smegmatis within macrophages.,A A Ganaie 2016,2016,2 genes,Ganaie-2016-Interaction of Erp Protein of Myco,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9281,PHI:7044,UniProt,P9WIQ7,GenBank,AAA96136,,,Mt103,RvErp,,,,Rv2212,UniProt: P9WMU7; GenBank: CCP44989,PHI:7045,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,exported repetitive protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; heterologous expression,,,YVS,27481930,PubMed,10.1128/JB.00120-16,J Bacteriol.2016 Sep 22;198(20):2841-52,chash71@yahoo.com,Increased cAMP production due to the interaction of RvErp with Rv2212 enhances the survival of M.smegmatis within macrophages.,A A Ganaie 2016,2016,2 genes,Ganaie-2016-Interaction of Erp Protein of Myco,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9282,PHI:7045,UniProt,P9WMU7,GenBank,CCP44989,,,H37Rv,Rv2212,,,,RvErp,UniProt: P9WIQ7; GenBank: AAA96136,PHI:7044,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,adenylylcyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; heterologous expression,,,YVS,27481930,PubMed,10.1128/JB.00120-16,J Bacteriol.2016 Sep 22;198(20):2841-52,chash71@yahoo.com,Increased cAMP production due to the interaction of RvErp with Rv2212 enhances the survival of M.smegmatis within macrophages.,A A Ganaie 2016,2016,2 genes,Ganaie-2016-Interaction of Erp Protein of Myco,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9283,PHI:7046,UniProt,A0A0D1C7C6,GenBank,XP_011389130,,,521,Aox1,chromosome 6,,,,,,5270,Ustilago maydis,559306,FB1; FB2,smut,monocots,4577,Zea mays (related: maize),,,,,mitochondrial alternative oxidase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,antimycin A,antimycin A: CHEBI:22584,,,,,gene deletion: full,,,YVS,28273139,PubMed,10.1371/journal.pone.0173389,PLoS One. 2017 Mar 8;12(3):e0173389,pardov@bq.unam.mx,"In both growth forms of U. maydis, i.e. yeast-like and hyphal growth, Aox1 is crucial to cope with respiratory stress.",C A C Monroy 2017,2017,1 gene,Cardenas-Monroy-2017-The mitochondrial alterna,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9284,PHI:7047,UniProt,U3PW09,GenBank,AGW81516,,,CNAG_01742,Aqp1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/J,,,,water channel protein aquaporin,,,HOG pathway,unaffected pathogenicity,,,,,,,,,,no,NaCl; KCl; sorbitol; H2O2; tert-butyl hydroperoxide,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090,,,,,gene mutation; gene complementation,,,YVS,28251810,PubMed,10.1111/1758-2229.12527,Environ Microbiol Rep. 2017 Mar 2,ysbahn@yonsei.ac.kr,Deletion of AQP1 increased hydrophobicity of the cell surface.,G L Meyers 2017,2017,1 gene,Meyers-2017-The water channel protein aquapori,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9285,PHI:7048,UniProt,Q5A663,GenBank,AOW29202,,,SC5314,Oma1,chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,intramitochondrial quality control protease,,,TOR pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,H2O2; NaCl; rapamycin; caffeine; vanillin; caspofungin,"H2O2: CHEBI:16240; NaCl: CHEBI:26710; rapamycin: CHEBI:9168; l,  caffeine: CHEBI:27732; vanillin: CHEBI:18346; caspofungin: CHEBI:474180; oligomycin: CHEBI:25675",,,,,gene deletion: full,,,YVS,27325672,PubMed,10.1128/MCB.00156-16,Mol Cell Biol. 2016 Aug 12;36(17):2300-12,okhalimonchuk2@unl.edu,The deletion mutant of oma1 exhibited increased resistance to PMN killing.,I Bohovych 2016,2016,1 gene,Bohovych-2016-Oma1 links mitochondrial protein,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9286,PHI:7049,UniProt,P9WJX9,GenBank,CCP44014,,,H37Rv,Rv1258c,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bone marrow-derived macrophage,tap efflux pump protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27324481,PubMed,10.1128/IAI.00072-16,Infect Immun.2016 Aug 19;84(9):2505-23,micas@nus.edu.sg,"Rv1258c mutant displayed increased susceptibility to killing by lysosomal SF and the antimicrobial peptide LL-37, as well as attenuated survival in primary murine macrophages and human macrophage cell line THP-1.",W Lin 2016,2016,1 gene,Lin-2016-Transcriptional profiling of Mycobact,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9287,PHI:7049,UniProt,P9WJX9,GenBank,CCP44014,,,H37Rv,Rv1258c,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,tap efflux pump protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27324481,PubMed,10.1128/IAI.00072-16,Infect Immun.2016 Aug 19;84(9):2505-23,micas@nus.edu.sg,"Rv1258c mutant displayed increased susceptibility to killing by lysosomal SF and the antimicrobial peptide LL-37, as well as attenuated survival in primary murine macrophages and human macrophage cell line THP-1.",W Lin 2016,2016,1 gene,Lin-2016-Transcriptional profiling of Mycobact,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9288,PHI:7056,UniProt,Q836D0,GenBank,AAO80984,,,V583,rnjB,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,spleen; kidney,RNase J2,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,28384222,PubMed,10.1371/journal.pone.0175212,PLoS One. 2017 Apr 6;12(4):e0175212,barrett.harvey@uth.tmc,E. faecalis RNase J2 deletion mutant was more sensitive to bile salt and greatly attenuated in in vivo organ infection as determined by an IV-sublethal challenge infection mouse model.,P Gao 2017,2017,1 gene,Gao-2017-Functional studies of E. faecalis RNa,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9289,PHI:7057,UniProt,J5K938,GenBank,EJP70646,,,ARSEF 2860,PilA,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,core eisosome protein,,,rapamycin (TOR) signalling pathway,reduced virulence,,,,,,increased; aberrant,,,wild type,no,H2O2; Congo red; NaCl; calcofluor white,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,28276124,PubMed,10.1111/1462-2920.13727,Environ Microbiol. 2017 May;19(5):2037-2052,yingsh@zju.edu.cn,All single/double deletion mutants of pil1A and pil1B lost almost all pathogenicity due to reduced ability to secrete Pr1 proteases for cuticle degradation.,L B Zhang 2017,2017,2 genes,Zhang-2017-Two eisosome proteins play opposite,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9290,PHI:7058,UniProt,J5JBK6,GenBank,EJP61316,,,ARSEF 2860,PilB,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,core eisosome protein,,,rapamycin (TOR) signalling pathway,reduced virulence,,,,,,aberrant,,,wild type,no,H2O2; Congo red; NaCl; calcofluor white,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,28276124,PubMed,10.1111/1462-2920.13727,Environ Microbiol. 2017 May;19(5):2037-2052,yingsh@zju.edu.cn,All single/double deletion mutants of pil1A and pil1B lost almost all pathogenicity due to reduced ability to secrete Pr1 proteases for cuticle degradation.,L B Zhang 2017,2017,2 genes,Zhang-2017-Two eisosome proteins play opposite,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9291,PHI:7057,UniProt,J5K938,GenBank,EJP70646,,,ARSEF 2860,PilA,,,,,,PHI:7058,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,core eisosome protein,,,rapamycin (TOR) signalling pathway,reduced virulence,,,,,,increased; aberrant,,,wild type,no,H2O2; Congo red; NaCl; calcofluor white,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,28276124,PubMed,10.1111/1462-2920.13727,Environ Microbiol. 2017 May;19(5):2037-2052,yingsh@zju.edu.cn,All single/double deletion mutants of pil1A and pil1B lost almost all pathogenicity due to reduced ability to secrete Pr1 proteases for cuticle degradation.,L B Zhang 2017,2017,2 genes,Zhang-2017-Two eisosome proteins play opposite,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9292,PHI:7058,UniProt,J5JBK6,GenBank,EJP61316,,,ARSEF 2860,PilB,,,,,,PHI:7057,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,core eisosome protein,,,rapamycin (TOR) signalling pathway,reduced virulence,,,,,,increased; aberrant,,,wild type,no,H2O2; Congo red; NaCl; calcofluor white,H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,28276124,PubMed,10.1111/1462-2920.13727,Environ Microbiol. 2017 May;19(5):2037-2052,yingsh@zju.edu.cn,All single/double deletion mutants of pil1A and pil1B lost almost all pathogenicity due to reduced ability to secrete Pr1 proteases for cuticle degradation.,L B Zhang 2017,2017,2 genes,Zhang-2017-Two eisosome proteins play opposite,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9293,PHI:7059,UniProt,P0C0F7,GenBank,AAY49386,,,8004,RpfC,,R15A; D17A; S18A; E19A; Q22A; S3A,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,receptor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28369120,PubMed,10.1371/journal.ppat.1006304,PLoS Pathog. 2017 Apr 3;13(4):e1006304,qianw@im.ac.cn,Disrupting direct DSF-RpfC interaction caused deficiency in bacterial virulence and biofilm development.,Z Cai 2017,2017,1 gene,Cai-2017-Fatty acid DSF binds and allosterical,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9294,PHI:7059,UniProt,P0C0F7,GenBank,AAY49386,,,8004,RpfC,,S18T,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,receptor histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28369120,PubMed,10.1371/journal.ppat.1006304,PLoS Pathog. 2017 Apr 3;13(4):e1006304,qianw@im.ac.cn,Disrupting direct DSF-RpfC interaction caused deficiency in bacterial virulence and biofilm development.,Z Cai 2017,2017,1 gene,Cai-2017-Fatty acid DSF binds and allosterical,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9295,PHI:7060,UniProt,Q83FA5,GenBank,AAO89610,,,RSA 493,CirA,,cirA::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II clone 4,Q fever,rodents,10090,Mus musculus (related: house mouse),C57BL/6<scid>,,,spleen,type IVb effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27324482,PubMed,10.1128/IAI.01554-15,Infect Immun. 2016 Aug 19;84(9):2524-33,jsamuel@medicine.tamhsc.edu,"Overexpression of CirA in mammalian cells results in cell rounding and stress fiber disruption, a phenotype that is rescued by overexpression of wild-type or constitutively active RhoA.",M M Weber 2016,2016,1 gene,Weber-2016-The type IV secreted effector prote,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9296,PHI:7061,UniProt,A0A0U1G333,GenBank,CNR65460,,,CH43,aroA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain BRD509,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; blood,3-phosphoshikimate 1-carboxyvinyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27456828,PubMed,10.1128/IAI.00337-16,Infect Immun. 2016 Sep 19;84(10):2833-41,sjmcsorley@ucdavis.edu,Mice lacking EPO receptor (EPOR) expression on nonerythroid cells (EPOR rescued) had bacterial loads similar to those of wild-type mice following Salmonella infection.,L X Li 2016,2016,5 genes,Li-2016-Salmonella Infection Enhances Erythrop,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9297,PHI:7062,UniProt,A0A0U1GNF3,GenBank,CNQ81581,,,CH43,aroD,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain BRD509,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; blood,3-dehydroquinate dehydratase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27456828,PubMed,10.1128/IAI.00337-16,Infect Immun. 2016 Sep 19;84(10):2833-41,sjmcsorley@ucdavis.edu,Mice lacking EPO receptor (EPOR) expression on nonerythroid cells (EPOR rescued) had bacterial loads similar to those of wild-type mice following Salmonella infection.,L X Li 2016,2016,5 genes,Li-2016-Salmonella Infection Enhances Erythrop,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9298,PHI:7063,UniProt,Q7BVH8,GenBank,AAC28876,,,SL1344,spiB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain BRD509,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; blood,Salmonella pathogenicity island 2 related secretion system apparatus protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27456828,PubMed,10.1128/IAI.00337-16,Infect Immun. 2016 Sep 19;84(10):2833-41,sjmcsorley@ucdavis.edu,Mice lacking EPO receptor (EPOR) expression on nonerythroid cells (EPOR rescued) had bacterial loads similar to those of wild-type mice following Salmonella infection.,L X Li 2016,2016,5 genes,Li-2016-Salmonella Infection Enhances Erythrop,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9299,PHI:7061,UniProt,A0A0U1G333,GenBank,CNR65460,,,CH43,aroA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain BRD509,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; blood,3-phosphoshikimate 1-carboxyvinyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27456828,PubMed,10.1128/IAI.00337-16,Infect Immun. 2016 Sep 19;84(10):2833-41,sjmcsorley@ucdavis.edu,Mice lacking EPO receptor (EPOR) expression on nonerythroid cells (EPOR rescued) had bacterial loads similar to those of wild-type mice following Salmonella infection.,L X Li 2016,2016,5 genes,Li-2016-Salmonella Infection Enhances Erythrop,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9300,PHI:7062,UniProt,A0A0U1GNF3,GenBank,CNQ81581,,,CH43,aroD,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain BRD509,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; blood,3-dehydroquinate dehydratase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27456828,PubMed,10.1128/IAI.00337-16,Infect Immun. 2016 Sep 19;84(10):2833-41,sjmcsorley@ucdavis.edu,Mice lacking EPO receptor (EPOR) expression on nonerythroid cells (EPOR rescued) had bacterial loads similar to those of wild-type mice following Salmonella infection.,L X Li 2016,2016,5 genes,Li-2016-Salmonella Infection Enhances Erythrop,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9301,PHI:7064,UniProt,A0A0T9V9T3,GenBank,CNQ54689,,,CH43,fliC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain BRD509,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; blood,flagellar biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27456828,PubMed,10.1128/IAI.00337-16,Infect Immun. 2016 Sep 19;84(10):2833-41,sjmcsorley@ucdavis.edu,Mice lacking EPO receptor (EPOR) expression on nonerythroid cells (EPOR rescued) had bacterial loads similar to those of wild-type mice following Salmonella infection.,L X Li 2016,2016,5 genes,Li-2016-Salmonella Infection Enhances Erythrop,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9302,PHI:7065,UniProt,A0A0T9VUV2,GenBank,CNR57494,,,CH43,fliB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain BRD509,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; blood,lysine-N-methylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27456828,PubMed,10.1128/IAI.00337-16,Infect Immun. 2016 Sep 19;84(10):2833-41,sjmcsorley@ucdavis.edu,Mice lacking EPO receptor (EPOR) expression on nonerythroid cells (EPOR rescued) had bacterial loads similar to those of wild-type mice following Salmonella infection.,L X Li 2016,2016,5 genes,Li-2016-Salmonella Infection Enhances Erythrop,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9303,PHI:7066,UniProt,A0A0E2ZL83,GenBank,APS91295,,,Schu4 F. tul Mut-127,CipR,,,,,,,263,Francisella tularensis,,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,ciprofloxacin resistance related,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28328947,PubMed,10.1371/journal.pone.0174106,PLoS One.2017 Mar 22;12(3):e0174106,joel.a.bozue.civ@mail.mil,The number of CFUs recovered from J774A.1 macrophage cells infected with CipR or kdsD::ltrBL1 mutant strains had decreased significantly as compared to CFU counts with the wildtype strain.,T Chance 2017,2017,2 genes,"Chance-2017-A spontaneous mutation in kdsD, a",BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9304,PHI:7067,UniProt,Q5NGP7,GenBank,YP_169795,,,SCHU S4,KdsD,,kdsD::ltrBL1,,,,,263,Francisella tularensis,,SCHU S4,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,D-arabinose 5-phosphate isomerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,28328947,PubMed,10.1371/journal.pone.0174106,PLoS One.2017 Mar 22;12(3):e0174106,joel.a.bozue.civ@mail.mil,The number of CFUs recovered from J774A.1 macrophage cells infected with CipR or kdsD::ltrBL1 mutant strains had decreased significantly as compared to CFU counts with the wildtype strain.,T Chance 2017,2017,2 genes,"Chance-2017-A spontaneous mutation in kdsD, a",BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9305,PHI:7068,UniProt,E0W544,GenBank,AEK80501,,,P7064,PsAvh23,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,root; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,28318979,PubMed,10.1016/j.cub.2017.02.044,Curr Biol. 2017 Apr 3;27(7):981-991,wangyc@njau.edu.cn,The results suggested that the virulence activity of PsAvh23 requires the nuclear localization in plant cells.,L Kong 2017,2017,1 gene,Kong-2017-A Phytophthora Effector Manipulates,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9306,PHI:7069,UniProt,A0A0E0USK4,GenBank,AEH91331,,,M7,htrA,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,secreted chaperone/protease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation. macrophage-like cell tissue",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9307,PHI:7070,UniProt,Q71XE6,GenBank,AAT05019,,,4b F2365,prsA2,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,secreted chaperone,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation. macrophage-like cell tissue",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9308,PHI:7069,UniProt,A0A0E0USK4,GenBank,AEH91331,,,M7,htrA,,,,,,PHI:7070,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,secreted chaperone/protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation. macrophage-like cell tissue",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9309,PHI:7070,UniProt,Q71XE6,GenBank,AAT05019,,,4b F2365,prsA2,,,,,,PHI:7069,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,secreted chaperone,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation. macrophage-like cell tissue",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9310,PHI:7069,UniProt,A0A0E0USK4,GenBank,AEH91331,,,M7,htrA,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,marsupials,9310,Potorous tridactylus (related: long-nosed potoroo),PtK2 cell line,,,renal epithelial cell,secreted chaperone/protease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9311,PHI:7070,UniProt,Q71XE6,GenBank,AAT05019,,,4b F2365,prsA2,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,marsupials,9310,Potorous tridactylus (related: long-nosed potoroo),PtK2 cell line,,,renal epithelial cell,secreted chaperone,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9312,PHI:7069,UniProt,A0A0E0USK4,GenBank,AEH91331,,,M7,htrA,,,,,,PHI:7070,1639,Listeria monocytogenes,393133,10403S,listeriosis,marsupials,9310,Potorous tridactylus (related: long-nosed potoroo),PtK2 cell line,,,renal epithelial cell,secreted chaperone/protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9313,PHI:7070,UniProt,Q71XE6,GenBank,AAT05019,,,4b F2365,prsA2,,,,,,PHI:7069,1639,Listeria monocytogenes,393133,10403S,listeriosis,marsupials,9310,Potorous tridactylus (related: long-nosed potoroo),PtK2 cell line,,,renal epithelial cell,secreted chaperone,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9314,PHI:7069,UniProt,A0A0E0USK4,GenBank,AEH91331,,,M7,htrA,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,secreted chaperone/protease,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9315,PHI:7070,UniProt,Q71XE6,GenBank,AAT05019,,,4b F2365,prsA2,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,secreted chaperone,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9316,PHI:7069,UniProt,A0A0E0USK4,GenBank,AEH91331,,,M7,htrA,,,,,,PHI:7070,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,secreted chaperone/protease,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9317,PHI:7070,UniProt,Q71XE6,GenBank,AAT05019,,,4b F2365,prsA2,,,,,,PHI:7069,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,secreted chaperone,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9318,PHI:7069,UniProt,A0A0E0USK4,GenBank,AEH91331,,,M7,htrA,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Henle cell line,,,renal epithelial cell,secreted chaperone/protease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9319,PHI:7070,UniProt,Q71XE6,GenBank,AAT05019,,,4b F2365,prsA2,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Henle cell line,,,renal epithelial cell,secreted chaperone,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9320,PHI:7069,UniProt,A0A0E0USK4,GenBank,AEH91331,,,M7,htrA,,,,,,PHI:7070,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Henle cell line,,,renal epithelial cell,secreted chaperone/protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9321,PHI:7070,UniProt,Q71XE6,GenBank,AAT05019,,,4b F2365,prsA2,,,,,,PHI:7069,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Henle cell line,,,renal epithelial cell,secreted chaperone,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,27481256,PubMed,10.1128/IAI.00312-16,Infect Immun. 2016 Sep 19;84(10):3034-46,nfreitag@uic.edu,"The introduction of a constitutively activated allele of prfA(prfA*) into prsA2 htrAstrains was found to essentially inhibit bacterial growth at 37°C in broth culture and ΔprsA2 ΔhtrA strains were additionally found to be defective for cell invasion and vacuole escape in selected cell types, steps that precede full PrfA activation.",J K Ahmed 2016,2016,2 genes,Ahmed-2016-Secretion Chaperones PrsA2 and HtrA,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9322,PHI:7071,,no data found,,,,,,TeA (tenuazonic acid),,deltaHP001 TeA toxin deficient mutant,,,,,5599,Alternaria alternata,,NEW,brown leaf spot,eudicots,176616,Ageratina adenophora (no common name found),,,,leaf,phytotoxin; photosystem II inhibitor,,,,reduced virulence,,yes,,,,,,aberrant,,no,,tenuazonic acid: CHEBI:9440,,,,,gene mutation; chemical complementation,,,YVS,28324684,PubMed,10.1016/j.plaphy.2017.03.002,Plant Physiol Biochem. 2017 Mar 4;115:73-82,wrl@njau.edu.cn,"Compared with the wild type, HP001 mutant lacking TeA produced morphologically different colonies, hyphae with thinner cell walls, had higher reactive oxygen species (ROS) content and lower peroxidase activity, and failed to form appressoria on the host surface. Tenuazonic acid addition to the mutant partially recovers these characteristics.",Y Kang 2017,2017,1 gene,Kang-2017-TeA is a key virulence factor for Al,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9323,PHI:7072,UniProt,Q5A650,GenBank,AOW29195,,,SC5314,sak1,chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract,serine/threonine kinase,,,,reduced virulence,,,,,,reduced; aberrant,,,,no,Congo red; caffeine; SDS,Congo red: CHEBI:34653; caffeine: CHEBI:27732; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28337802,PubMed,10.1111/mmi.13674,Mol Microbiol. 2017 Mar 23,joachim.morschhaeuser@uni-wuerzburg.de,Snf1-activating kinase Sak1 of C.albicans is a key regulator of Snf1 that is essential for metabolic adaptation and in vivo fitness of this opportunistic fungal pathogen.,B R Zavala 2017,2017,2 genes,Ramirez-Zavala-2017-The Snf1-activating kinase,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9324,PHI:7073,UniProt,P52497,GenBank,AAB48643,,,B311,snf1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,gastrointestinal tract,serine/threonine kinase,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,YVS,28337802,PubMed,10.1111/mmi.13674,Mol Microbiol. 2017 Mar 23,joachim.morschhaeuser@uni-wuerzburg.de,"Snf1-activating kinase Sak1 of C.albicans is a key regulator of Snf1 that is essential for metabolic adaptation and in vivo fitness of this opportunistic fungal pathogen. Failed to generate homozgous SNF1 mutants, although either of the two alleles could be deleted in heterozygous mutants.",B R Zavala 2017,2017,2 genes,Ramirez-Zavala-2017-The Snf1-activating kinase,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9325,PHI:7074,UniProt,Q4WIG8,GenBank,XP_749325,,,A1163,rtfa,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RNA polymerase II transcription elongation factor-like protein,,,,reduced virulence,,,,,,,,reduced,,no,Congo red; SDS; 6-azauracil; nikkomycin Z; sorbitol; KCl; sucrose; menadione,Congo red: CHEBI:34653; SDS: CHEBI:8984; 6-azauracil: CHEBI:53745; nikkomycin Z: CHEBI:623918; sorbitol: CHEBI:30911; KCl: CHEBI:32588; sucrose: CHEBI:17992; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,28453536,PubMed,10.1371/journal.pone.0176702,PLoS One. 2017 Apr 28;12(4):e0176702,amcalvo@niu.edu,"RtfA influenced productionof various secondary metabolites, protease activity levels, sensitivity to oxidative stress and adhesion capacity.",R R Myers 2017,2017,1 gene,"Myers-2017-rtfA controls development, secondar",BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9326,PHI:7074,UniProt,Q4WIG8,GenBank,XP_749325,,,A1163,rtfa,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),Hsd:ICR,,,eye; nasal cavity; mouth,RNA polymerase II transcription elongation factor-like protein,,,,reduced virulence,,,,,,,,reduced,,no,Congo red; SDS; 6-azauracil; nikkomycin Z; sorbitol; KCl; sucrose; menadione,Congo red: CHEBI:34653; SDS: CHEBI:8984; 6-azauracil: CHEBI:53745; nikkomycin Z: CHEBI:623918; sorbitol: CHEBI:30911; KCl: CHEBI:32588; sucrose: CHEBI:17992; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,28453536,PubMed,10.1371/journal.pone.0176702,PLoS One. 2017 Apr 28;12(4):e0176702,amcalvo@niu.edu,"RtfA influenced productionof various secondary metabolites, protease activity levels, sensitivity to oxidative stress and adhesion capacity.",R R Myers 2017,2017,1 gene,"Myers-2017-rtfA controls development, secondar",BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9327,PHI:7075,UniProt,B3GXB6,GenBank,ACE61268,,,AP76,pdxS,,,,,,,715,Actinobacillus pleuropneumoniae,1224142,S8,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; kidney,encodes the putative pyridoxal 5'-phosphate synthase subunit PdxS,,,pyridoxal 5'-phosphate biosynthesis pathway,reduced virulence,,,,,,,,reduced,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: partial; gene complementation,,,YVS,28448619,PubMed,10.1371/journal.pone.0176374,PLoS One. 2017 Apr 27;12(4):e0176374,chunlai.w@hvri.ac.cn,The reduced growth of the pdxS and pdxT deletion mutants under osmotic and oxidative stress conditions suggested that the PLP synthases PdxS/PdxT were associated with the stress tolerance of A. pleuropneumoniae.,F Xie 2017,2017,2 genes,Xie-2017-Pyridoxal phosphate synthases PdxS_Pd,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9328,PHI:7076,UniProt,B3GXB7,GenBank,ACE61269,,,AP76,pdxT,,,,,,,715,Actinobacillus pleuropneumoniae,1224142,S8,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; kidney,encodes the putative pyridoxal 5'-phosphate synthase subunit PdxT,,,pyridoxal 5'-phosphate biosynthesis pathway,reduced virulence,,,,,,,,reduced,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: partial; gene complementation,,,YVS,28448619,PubMed,10.1371/journal.pone.0176374,PLoS One. 2017 Apr 27;12(4):e0176374,chunlai.w@hvri.ac.cn,The reduced growth of the pdxS and pdxT deletion mutants under osmotic and oxidative stress conditions suggested that the PLP synthases PdxS/PdxT were associated with the stress tolerance of A. pleuropneumoniae.,F Xie 2017,2017,2 genes,Xie-2017-Pyridoxal phosphate synthases PdxS_Pd,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9329,PHI:7077,UniProt,A0A1W5X9P3,GenBank,ARH19411,,,,ClVelB,,,,ClVeA; ClVosA,GenBank: ARH19410; GenBank: ARH19412,,5503,Curvularia lunata,1263492,CX-3,Curvularia leaf spot,monocots,4577,Zea mays (related: maize),cv. Huangzao 4,,,leaf,velvet protein which controls the production of conidia and the methyl 5-(hydroxymethyl) furan-2-carboxylate toxin,,,glycerol biosynthesis pathway; cell wall integrity (CWI) pathway,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,NaCl; KCl; iprodione; fludioxonil; H2O2; Congo red; caffeine; SDS,"NaCl: CHEBI:26710; KCl: CHEBI:32588; iprodione: CHEBI:28909, CAS:36734-19-7; fludioxonil: CHEBI:81763; H2O2: CHEBI:16240; Congo red: CHEBI:34653; caffeine: CHEBI:27732; SDS: CHEBI:8984",,,,,gene deletion: full; gene complementation,,,YVS,28393907,PubMed,10.1038/srep46054,Sci Rep. 2017 Apr 10;7:46054,jiechen59@sjtu.edu.cn,The deletion of clvelB led to the increase in aerial hyphae and melanin formation.,J X Gao 2017,2017,1 gene,Gao-2017-Involvement of a velvet protein ClVel,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9330,PHI:7078,UniProt,D4I222,GenBank,CBA23258,,,CFPB1430,tssA-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-661,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9331,PHI:7079,UniProt,D4I208,GenBank,CBA23229,,,CFPB1430,tssA-3,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-662,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9332,PHI:7080,UniProt,D4I235,GenBank,CBA23284,,,CFPB1430,tssB-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-663,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9333,PHI:7081,UniProt,D4I234,GenBank,CBA23281,,,CFPB1430,tssC-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-664,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9334,PHI:7082,UniProt,D4I209,GenBank,CBA23231,,,CFPB1430,tssE-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-665,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9335,PHI:7083,UniProt,D4I221,GenBank,CBA23255,,,CFPB1430,tssF-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-666,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9336,PHI:7084,UniProt,D4I0P5,GenBank,CBA22846,,,CFPB1430,tssG-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-667,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9337,PHI:7085,UniProt,D4I220,GenBank,CBA23253,,,CFPB1430,tssG-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-668,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9338,PHI:7086,UniProt,D4I219,GenBank,CBA23251,,,CFPB1430,tssJ-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-669,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9339,PHI:7087,UniProt,D4I0R5,GenBank,CBA22887,,,CFPB1430,tssK-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-670,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9340,PHI:7088,UniProt,D4I233,GenBank,CBA23279,,,CFPB1430,tssK-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-671,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9341,PHI:7089,UniProt,D4I232,GenBank,CBA23277,,,CFPB1430,tssL-3,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-672,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9342,PHI:7090,UniProt,D4I0R3,GenBank,CBA22883,,,CFPB1430,tssM-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-673,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9343,PHI:7091,UniProt,D4I223,GenBank,CBA23260,,,CFPB1430,tssM-3,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-674,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9344,PHI:7092,UniProt,D4I0N9,GenBank,CBA22834,,,CFPB1430,vgrG-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-675,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9345,PHI:7093,UniProt,D4I227,GenBank,CBA23268,,,CFPB1430,vgrG-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-676,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9346,PHI:7094,UniProt,D4I229,GenBank,CBA23271,,,CFPB1430,clpV-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-3 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-677,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9347,PHI:7095,UniProt,D4I0Q1,GenBank,CBA22859,,,CFPB1430,tagH-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-678,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9348,PHI:7096,UniProt,D4I1S9,GenBank,CBA20570,,,CFPB1430,tagH-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-2 component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-679,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9349,PHI:7097,UniProt,D4I0R1,GenBank,CBA22879,,,CFPB1430,tssA-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-680,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9350,PHI:7098,UniProt,D4I0R0,GenBank,CBA22876,,,CFPB1430,tssB-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-681,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9351,PHI:7099,UniProt,D4I0Q9,GenBank,CBA22875,,,CFPB1430,tssC-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-682,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9352,PHI:7100,UniProt,D4I0P7,GenBank,CBA22850,,,CFPB1430,tssE-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-683,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9353,PHI:7101,UniProt,D4I0P6,GenBank,CBA22848,,,CFPB1430,tssF-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-684,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9354,PHI:7102,UniProt,D4I0R6,GenBank,CBA22889,,,CFPB1430,tssJ-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-685,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9355,PHI:7103,UniProt,D4I0R4,GenBank,CBA22885,,,CFPB1430,tssL-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-686,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9356,PHI:7104,UniProt,D4I1T2,GenBank,CBA20573,,,CFPB1430,tssL-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-2 component,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-687,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9357,PHI:7105,UniProt,D4I1T1,GenBank,CBA20572,,,CFPB1430,tssM-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-2 component,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-688,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9358,PHI:7106,UniProt,D4I0P4,GenBank,CBA22845,,,CFPB1430,clpV-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS-1 component,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-689,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9359,PHI:7107,UniProt,D4I0Q8,GenBank,CBA22873,,,CFPB1430,hcp-1,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-690,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9360,PHI:7108,UniProt,D4I230,GenBank,CBA23273,,,CFPB1430,hcp-2,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-691,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9361,PHI:7109,UniProt,D4I0P2,GenBank,CBA22840,,,CFPB1430,vgrG-3,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-692,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9362,PHI:7110,UniProt,D4I218,GenBank,CBA23250,,,CFPB1430,vgrG-4,,,,,,,552,Erwinia amylovora,,NCPPB 1665,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan,,,fruit,T6SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28421913,PubMed,10.1094/PHYTO-11-16-0393-R,Phytopathology. 2017 Jun;107(6):654-693,hbs@njau.edu.cn,19 Mutants produced less amylovoran or levan or both suggesting the possible link between virulence reductions in the T6SS mutants with EPS production.,Y Tian 2017,2017,33 genes,Tian-2017-Type VI Secretion Systems of Erwinia,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9363,PHI:7111,UniProt,I1RE49,GenBank,CEF74128,,,PH-1,FgCAP1,chromosome 1,,,Fac1,GenBank: XP_011317009,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,adenylate-binding protein,,,trichothecene mycotoxin deoxynivalenol biosynthesis,reduced virulence,,,,,,aberrant,wild type,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28142217,PubMed,10.1111/mpp.12540,MolPlantPathol.2017 Jan 31,jinrong@purdue.edu,"Phosphorylation of FgCap1 at S353 is important for vegetative growth and plant infection, but dispensable for asexual reproduction and DON biosynthesis.",T Yin 2017,2017,1 gene,Yin-2017-The cyclase-associated protein FgCap1,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9364,PHI:7112,UniProt,G4MRH1,GenBank,EHA56598,,,70-15,MoERR1,chromosome 1,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,endoplasmic reticulum retention receptor required for function and integrity of ER,,,,reduced virulence,,,yes,yes,,reduced; aberrant,,reduced,reduced,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,gene disruption; gene complementation,,,YVS,28455525,PubMed,10.1038/s41598-017-01237-x,Sci Rep. 2017 Apr 28;7(1):1259,yonglee@snu.ac.kr,"Targeted disruption of MoERR1 showed pleiotropic effects on phenotypes, while deletion of MoERR2 had no effect on phenotypes examined.",J Goh 2017,2017,2 genes,"Goh-2017-ER retention receptor, MoERR1 is requ",BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9365,PHI:7113,UniProt,G4N6R6,GenBank,EHA49883,,,70-15,MoERR2,chromosome 4,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,endoplasmic reticulum retention receptor required for function and integrity of ER,,,,unaffected pathogenicity,,,,,,,,wild type,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,gene deletion: full,,,YVS,28455525,PubMed,10.1038/s41598-017-01237-x,Sci Rep. 2017 Apr 28;7(1):1259,yonglee@snu.ac.kr,"Targeted disruption of MoERR1 showed pleiotropic effects on phenotypes, while deletion of MoERR2 had no effect on phenotypes examined.",J Goh 2017,2017,2 genes,"Goh-2017-ER retention receptor, MoERR1 is requ",BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9366,PHI:7114,UniProt,E9E402,GenBank,EFY89414,,,CQMa102,Crz1,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,wing,calcineurin-responsive zinc finger transcription factor; pathogenicity factor,,,"calcineurin signaling pathway, MAPK cascades, cAMP-dependent pathway and GTPase signaling pathway",reduced virulence,,yes,,,,aberrant,,wild type,reduced,no,sodium dodecyl sulfate; calcofluor white; Congo red; NaCl; sorbitol; H2O2,sodium dodecyl sulfate: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28424845,PubMed,10.1007/s00253-017-8290-9,Appl Microbiol Biotechnol. 2017 Apr 19,yuxianxia@cqu.edu.cn,"The mutant displayed increased sensitivity to oxidative stress, cell wall perturbing agents, heat stress and ultraviolet irradiation as compared to the wild-type.",X Chen 2017,2017,1 gene,Chen-2017-The regulatory role of the transcrip,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9367,PHI:7115,UniProt,I6Y9F7,GenBank,CCP45279,,,H37Rv,LipQ,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell wall associated putative esterase/ lipase which is involved in the lipid/ester metabolism,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,YVS,28412202,PubMed,10.1016/j.micpath.2017.04.015,Microb Pathog. 2017 Apr 12;107:361-367,anjanibhu@gmail.com,"rLipQ stimulation caused not only significant reduction in the expression of iNOS and NF-kB, but also lowered the level of pro- and increased level of anti-inflammatory cytokines leading to the enhancement in bacillary survival.",A Kumar 2017,2017,1 gene,Kumar-2017-The immunosuppressive effects of a,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9368,PHI:7116,UniProt,J9R8H9,GenBank,YP_006723622,,,RA-CH-1,wza,,,,,,,34085,Riemerella anatipestifer,1228997,RA-CH-1,septicemia; serositis,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood,conserved outer membrane lipoprotein,,,capsular polysaccharide biosynthesis pathway,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28442426,PubMed,10.1016/j.micpath.2017.04.023,Microb Pathog. 2017 Apr 22;107:442-450,mshwang@163.com,The deletion of the wza gene had significantly increased biofilm formation capacity.,H Yi 2017,2017,1 gene,Yi-2017-Identification of a wza-like gene invo,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9369,PHI:7117,UniProt,G4NH08,GenBank,EHA47518,,,70-15,MoGSK1,chromosome 6,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"glycogen synthase kinase, central signal regulator involved in the stress-responsive mechanism",,,MAPK signaling pathway and cell wall integrity pathway,loss of pathogenicity,,no,yes,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28424497,PubMed,10.1038/s41598-017-01006-w,,n.j.talbot@exeter.ac.uk,The MoGSK1 overexpression resulted in production of elongated appressoria on hydrophobic cover slips which were fully capable of penetrating the plant surface and differentiate into invasive hyphae that displayed similar aggression as the Guy11 strain.,T Zhou 2017,2017,1 gene,Zhou-2017-The glycogen synthase kinase MoGsk1,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9370,PHI:7117,UniProt,G4NH08,GenBank,EHA47518,,,70-15,MoGSK1,chromosome 6,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. CDC Silky,,,leaf,"glycogen synthase kinase, central signal regulator involved in the stress-responsive mechanism",,,MAPK signaling pathway and cell wall integrity pathway,loss of pathogenicity,,no,yes,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28424497,PubMed,10.1038/s41598-017-01006-w,Sci Rep. 2017 Apr 19;7(1):945,n.j.talbot@exeter.ac.uk,The MoGSK1 overexpression resulted in production of elongated appressoria on hydrophobic cover slips which were fully capable of penetrating the plant surface and differentiate into invasive hyphae that displayed similar aggression as the Guy11 strain.,T Zhou 2017,2017,1 gene,Zhou-2017-The glycogen synthase kinase MoGsk1,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9371,PHI:7118,UniProt,A0A0H2URT4,GenBank,AAK75965,,,TIGR4,gtfA,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,glycosyltransferase known to attach GlcNAc to SRRPs,,,glycosylation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28408270,PubMed,10.1016/j.micinf.2017.04.001,Microbes Infect. 2017 Apr 10. pii: S1286-4579(17)30043-6,corihuel@uab.edu,"Deletion of gtfA and gtfB did not affect transcription of psrP, thereby suggested that it was PsrP protein stability that was most likely negatively affected by deletion of GtfA and GtfB. type II lung epithelial cell tissue",A Lizcano 2017,2017,3 genes,Lizcano-2017-Transcriptional organization of p,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9372,PHI:7119,UniProt,G6LPL3,GenBank,EHD56520,,,GA44500,gtfB,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,glycosyltransferase known to attach GlcNAc to SRRPs,,,glycosylation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28408270,PubMed,10.1016/j.micinf.2017.04.001,Microbes Infect. 2017 Apr 10. pii: S1286-4579(17)30043-6,corihuel@uab.edu,"Deletion of gtfA and gtfB did not affect transcription of psrP, thereby suggested that it was PsrP protein stability that was most likely negatively affected by deletion of GtfA and GtfB. type II lung epithelial cell tissue",A Lizcano 2017,2017,3 genes,Lizcano-2017-Transcriptional organization of p,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9373,PHI:7120,UniProt,A0A0U0B015,GenBank,COC00526,,,SMRU626,psrP,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,glycoprotein that mediates Streptococcus pneumoniae attachment to lung cells and promotes biofilm formation,,,glycosylation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28408270,PubMed,10.1016/j.micinf.2017.04.001,Microbes Infect. 2017 Apr 10. pii: S1286-4579(17)30043-6,corihuel@uab.edu,"Deletion of gtfA and gtfB did not affect transcription of psrP, thereby suggested that it was PsrP protein stability that was most likely negatively affected by deletion of GtfA and GtfB. type II lung epithelial cell tissue",A Lizcano 2017,2017,3 genes,Lizcano-2017-Transcriptional organization of p,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9374,PHI:7118,UniProt,A0A0H2URT4,GenBank,AAK75965,,,TIGR4,gtfA,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,lung; blood,glycosyltransferase known to attach GlcNAc to SRRPs,,,glycosylation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28408270,PubMed,10.1016/j.micinf.2017.04.001,Microbes Infect. 2017 Apr 10. pii: S1286-4579(17)30043-6,corihuel@uab.edu,"Deletion of gtfA and gtfB did not affect transcription of psrP, thereby suggested that it was PsrP protein stability that was most likely negatively affected by deletion of GtfA and GtfB.",A Lizcano 2017,2017,3 genes,Lizcano-2017-Transcriptional organization of p,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9375,PHI:7119,UniProt,G6LPL3,GenBank,EHD56520,,,GA44500,gtfB,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,lung; blood,glycosyltransferase known to attach GlcNAc to SRRPs,,,glycosylation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28408270,PubMed,10.1016/j.micinf.2017.04.001,Microbes Infect. 2017 Apr 10. pii: S1286-4579(17)30043-6,corihuel@uab.edu,"Deletion of gtfA and gtfB did not affect transcription of psrP, thereby suggested that it was PsrP protein stability that was most likely negatively affected by deletion of GtfA and GtfB.",A Lizcano 2017,2017,3 genes,Lizcano-2017-Transcriptional organization of p,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9376,PHI:7120,UniProt,A0A0U0B015,GenBank,COC00526,,,SMRU626,psrP,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,lung; blood,glycoprotein that mediates Streptococcus pneumoniae attachment to lung cells and promotes biofilm formation,,,glycosylation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28408270,PubMed,10.1016/j.micinf.2017.04.001,Microbes Infect. 2017 Apr 10. pii: S1286-4579(17)30043-6,corihuel@uab.edu,"Deletion of gtfA and gtfB did not affect transcription of psrP, thereby suggested that it was PsrP protein stability that was most likely negatively affected by deletion of GtfA and GtfB.",A Lizcano 2017,2017,3 genes,Lizcano-2017-Transcriptional organization of p,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9377,PHI:7121,UniProt,B0YCA2,GenBank,EDP48233,,,A1163,tslA,,,,CsmA,UniProt: B0XTE0; GenBank: EDP54849,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,trehalose-phosphate synthase subunit,,,trehalose biosynthesis pathway,increased virulence (hypervirulence),,,,,,,,wild type,reduced,no,Congo red; calcofluor white; caspofungin; sorbitol,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911,,,,,gene mutation; gene complementation,,,YVS,28442603,PubMed,10.1128/mBio.00056-17,MBio. 2017 Apr 25;8(2). pii: e00056-17,Robert.A.Cramer.JR@dartmouth.edu,"Increased chitin levels and the decreased beta-glucan levels on the cell wall of the ΔtslA strain alter the immunopathogenesis of murine IPA through increased and differential recruitment of inflammatory cells, likely through alterations in the secretion of proinflammatory cytokines.",A Thammahong 2017,2017,1 gene,Thammahong-2017-Aspergillus fumigatus Trehalos,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9378,PHI:7122,,no data found,GenBank,ABO10601,,,ATCC 17978,A1S_0114,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,virulence related acyl carrier protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28421168,PubMed,10.3389/fcimb.2017.00108,Front Cell Infect Microbiol. 2017 Apr 3;7:108,actisla@miamioh.edu,Deletion of A1S_0114 significantly affected bacterial adherence and biofilm biogenesis.,S Rumbo-Feal 2017,2017,1 gene,Rumbo-Feal-2017-Contribution of the A. baumann,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9379,PHI:7122,,no data found,GenBank,ABO10601,,,ATCC 17978,A1S_0114,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,virulence related acyl carrier protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28421168,PubMed,10.3389/fcimb.2017.00108,Front Cell Infect Microbiol. 2017 Apr 3;7:108,actisla@miamioh.edu,Deletion of A1S_0114 significantly affected bacterial adherence and biofilm biogenesis.,S Rumbo-Feal 2017,2017,1 gene,Rumbo-Feal-2017-Contribution of the A. baumann,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9380,PHI:7122,,no data found,GenBank,ABO10601,,,ATCC 17978,A1S_0114,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,virulence related acyl carrier protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28421168,PubMed,10.3389/fcimb.2017.00108,Front Cell Infect Microbiol. 2017 Apr 3;7:108,actisla@miamioh.edu,Deletion of A1S_0114 significantly affected bacterial adherence and biofilm biogenesis.,S Rumbo-Feal 2017,2017,1 gene,Rumbo-Feal-2017-Contribution of the A. baumann,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9381,PHI:7123,UniProt,A0A098DK45,GenBank,XP_011321275,,,PH-1; NRRL 31084,Fgvps39,,,,FgVam7; FgSso1,GenBank: EYB28243; GenBank: XP_011316692,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower; seedling; kernel,involved in vesicle trafficking from early or late endosomes to vacuoles,,,vesicle trafficking pathway,reduced virulence,yes,,yes,yes,,reduced; aberrant,reduced,reduced,,no,NaCl; KCl; sorbitol; H2O2; azoxystrobin; carbendazim; tebuconazole,"NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; azoxystrobin: CHEBI:40909, CAS:131860-33-8; carbendazim: CHEBI:3392, CAS:10605-21-7; tebuconazole: CHEBI:81781",,,,,gene deletion: full; gene complementation,,,YVS,28437167,PubMed,10.1094/MPMI-11-16-0242-R,Mol Plant Microbe Interact. 2017 May;30(5):410-422,hfzhang@njau.edu.cn,"Fgvps39 mutant was defective in vacuole morphology and autophagy, and it was delayed in endocytosis.",B Li 2017,2017,1 gene,Li-2017-The FgVps39-FgVam7-FgSso1 Complex Medi,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9382,PHI:7123,UniProt,A0A098DK45,GenBank,XP_011321275,,,PH-1; NRRL 31084,Fgvps39,,,,FgVam7; FgSso1,GenBank: EYB28243; GenBank: XP_011316692,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,stem,involved in vesicle trafficking from early or late endosomes to vacuoles,,,vesicle trafficking pathway,reduced virulence,yes,,yes,yes,,reduced; aberrant,reduced,reduced,,no,NaCl; KCl; sorbitol; H2O2; azoxystrobin; carbendazim; tebuconazole,"NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; azoxystrobin: CHEBI:40909, CAS:131860-33-8; carbendazim: CHEBI:3392, CAS:10605-21-7; tebuconazole: CHEBI:81781",,,,,gene deletion: full; gene complementation,,,YVS,28437167,PubMed,10.1094/MPMI-11-16-0242-R,Mol Plant Microbe Interact. 2017 May;30(5):410-422,hfzhang@njau.edu.cn,"Fgvps39 mutant was defective in vacuole morphology and autophagy, and it was delayed in endocytosis.",B Li 2017,2017,1 gene,Li-2017-The FgVps39-FgVam7-FgSso1 Complex Medi,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9383,PHI:7124,UniProt,I1RRB0,GenBank,CEF82959,,,PH-1,FgEB1,chromosome 4,,,FgKar9; FgCDC3; FgCDC10; FgCDC11; FgCDC12,UniProt: I1RAM0; GenBank: CEF72504; UniProt: I1RMW3; GenBank: CEF87389; UniProt: I1RPQ7; Gen,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower; spikelet; kernel,microtubule end-binding protein,,,trichothecene biosynthetic pathway,reduced virulence,,,,,,increased; aberrant,,reduced; aberrant,increased,no,phenamacril; carbendazim,"phenamacril: CAS:3336-69-4; carbendazim: CHEBI:3392, CAS:10605-21-7",,,,,gene deletion: full; gene complementation,,,YVS,28028881,PubMed,10.1111/1462-2920.13651,Environ Microbiol. 2017 May;19(5):1791-1807,ynyin@zju.edu.cn,"Deletion mutant (ΔFgEB1) of Fusarium graminearum exhibits twisted hyphae, increased hyphal branching and curved conidia, indicating that FgEB1 is involved in the regulation of cellular polarity.",Z Liu 2017,2017,2 genes,Liu-2017-The microtubule end-binding protein F,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9384,PHI:7125,UniProt,I1RAM0,GenBank,CEF72504,,,PH-1,FgKar9,chromosome 1,,,FgEB1,UniProt: I1RRB0; GenBank: CEF82959,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,cortical protein,,,,unaffected pathogenicity,,,,,,,,,wild type,no,phenamacril; carbendazim; tebuconazole; iprodione; rapamycin; fludioxonil; fluconazole; congo red; NaCl; pyrimethanil; CaCl2; paraquat,"phenamacril: CAS:3336-69-4; carbendazim: CHEBI:3392, CAS:10605-21-7; tebuconazole: CHEBI:81781; iprodione: CHEBI:28909, CAS:36734-19-7; rapamycin: CHEBI:9168; l,  fludioxonil: CAS:131341-86-1; Congo red: CHEBI:34653; NaCl: CHEBI:26710; fluconazole: CHEBI:46081, CAS:86386-73-4; pyrimethanil: CHEBI:8674; CaCl2: CHEBI:3312; paraquat: CHEBI:34905",,,,,gene deletion: partial,,,YVS,28028881,PubMed,10.1111/1462-2920.13651,Environ Microbiol. 2017 May;19(5):1791-1807,ynyin@zju.edu.cn,"Deletion mutant (ΔFgEB1) of Fusarium graminearum exhibited twisted hyphae, increased hyphal branching and curved conidia, indicating that FgEB1 was involved in the regulation of cellular polarity.",Z Liu 2017,2017,2 genes,Liu-2017-The microtubule end-binding protein F,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9385,PHI:7126,UniProt,A0A1B4Z8V7,GenBank,BAV55829,,,JMUB1235,sof,,,,,,,1314,Streptococcus pyogenes,410076,serotype M89 strain MGAS27556,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,limb; fascia; muscle,cell surface virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28435893,PubMed,10.1128/mSphereDirect.00147-17,mSphere. 2017 Apr 19;2(2). pii: e00147-17,jmmusser@houstonmethodist.org.,There was no significant difference in the magnitude of virulence attenuation of Δsof-OD and Δsof mutant strains.,L Zhu 2017,2017,1 gene,Zhu-2017-Opacification Domain of Serum Opacity,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9386,PHI:7126,UniProt,A0A1B4Z8V7,GenBank,BAV55829,,,JMUB1235,sof,,Δsof-FD,,,,,1314,Streptococcus pyogenes,410076,serotype M89 strain MGAS27556,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,limb; fascia; muscle,cell surface virulence factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,28435893,PubMed,10.1128/mSphereDirect.00147-17,mSphere. 2017 Apr 19;2(2). pii: e00147-17,jmmusser@houstonmethodist.org.,Deletion of the SOF fibronectin-binding domain alone (Δsof-FD strain) did not significantly alter virulence in the bacteremia model.,L Zhu 2017,2017,1 gene,Zhu-2017-Opacification Domain of Serum Opacity,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9387,PHI:7127,UniProt,Q3BM44,GenBank,CAJ26169,,,85-10,XopQ,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,28423458,PubMed,10.1111/tpj.13578,Plant J. 2017 Apr 19,norman.adlung@genetik.uni-halle.de,"Host gene alteration data available for EDS1. XopQ-dependent cell death suppression in N. benthamiana does not reflect the virulence activity, but rather is a side effect of plant ETI, induced by XopQ recognition.",N Adlung 2017,2017,1 gene,Adlung-2017-Dissecting virulence function from,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9388,PHI:7127,UniProt,Q3BM44,GenBank,CAJ26169,,,85-10,XopQ,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,28423458,PubMed,10.1111/tpj.13578,Plant J. 2017 Apr 19,norman.adlung@genetik.uni-halle.de,"XopQ-dependent cell death suppression in N. benthamiana does not reflect the virulence activity, but rather is a side effect of plant ETI, induced by XopQ recognition.",N Adlung 2017,2017,1 gene,Adlung-2017-Dissecting virulence function from,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9389,PHI:7128,UniProt,D3VBH2,GenBank,CBJ89611,,,ATCC 19061,lrp,,,,,,,628,Xenorhabdus nematophila,,ATCC 19061,,moths,7130,Manduca sexta (related: tobacco hornworm),,,,larva,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28411220,PubMed,10.1128/AEM.00185-17,Appl Environ Microbiol.2017 Apr 14. pii: AEM.00185-17,hgblair@utk.edu,The evidence suggested that the underlying cause of high-Lrp-dependent virulence attenuation in M. sexta is hypersensitivity to host immune responses and decreased insecticidal activity and that high-Lrp virulence phenotypes are insect-host specific.,Á M C Torres 2017,2017,1 gene,Casanova-Torres-2017-The global transcription,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9390,PHI:7128,UniProt,D3VBH2,GenBank,CBJ89611,,,ATCC 19061,lrp,,,,,,,628,Xenorhabdus nematophila,,ATCC 19061,,moths,7130,Manduca sexta (related: tobacco hornworm),,,,larva,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28411220,PubMed,10.1128/AEM.00185-17,Appl Environ Microbiol.2017 Apr 14. pii: AEM.00185-17,hgblair@utk.edu,The evidence suggested that the underlying cause of high-Lrp-dependent virulence attenuation in M. sexta is hypersensitivity to host immune responses and decreased insecticidal activity and that high-Lrp virulence phenotypes are insect-host specific.,Á M C Torres 2017,2017,1 gene,Casanova-Torres-2017-The global transcription,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9391,PHI:7128,UniProt,D3VBH2,GenBank,CBJ89611,,,ATCC 19061,lrp,,,,,,,628,Xenorhabdus nematophila,,ATCC 19061,,moths,7130,Manduca sexta (related: tobacco hornworm),,,,larva,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: downregulation,,,YVS,28411220,PubMed,10.1128/AEM.00185-17,Appl Environ Microbiol.2017 Apr 14. pii: AEM.00185-17,hgblair@utk.edu,The evidence suggested that the underlying cause of high-Lrp-dependent virulence attenuation in M. sexta is hypersensitivity to host immune responses and decreased insecticidal activity and that high-Lrp virulence phenotypes are insect-host specific.,Á M C Torres 2017,2017,1 gene,Casanova-Torres-2017-The global transcription,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9392,PHI:7128,UniProt,D3VBH2,GenBank,CBJ89611,,,ATCC 19061,lrp,,,,,,,628,Xenorhabdus nematophila,,ATCC 19061,,flies,7227,Drosophila melanogaster (related: fruit fly),,,,adult,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28411220,PubMed,10.1128/AEM.00185-17,Appl Environ Microbiol.2017 Apr 14. pii: AEM.00185-17,hgblair@utk.edu,The evidence suggested that the underlying cause of high-Lrp-dependent virulence attenuation in M. sexta is hypersensitivity to host immune responses and decreased insecticidal activity and that high-Lrp virulence phenotypes are insect-host specific.,Á M C Torres 2017,2017,1 gene,Casanova-Torres-2017-The global transcription,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9393,PHI:7128,UniProt,D3VBH2,GenBank,CBJ89611,,,ATCC 19061,lrp,,,,,,,628,Xenorhabdus nematophila,,ATCC 19061,,flies,7227,Drosophila melanogaster (related: fruit fly),,,,adult,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28411220,PubMed,10.1128/AEM.00185-17,Appl Environ Microbiol.2017 Apr 14. pii: AEM.00185-17,hgblair@utk.edu,The evidence suggested that the underlying cause of high-Lrp-dependent virulence attenuation in M. sexta is hypersensitivity to host immune responses and decreased insecticidal activity and that high-Lrp virulence phenotypes are insect-host specific.,Á M C Torres 2017,2017,1 gene,Casanova-Torres-2017-The global transcription,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9394,PHI:7128,UniProt,D3VBH2,GenBank,CBJ89611,,,ATCC 19061,lrp,,,,,,,628,Xenorhabdus nematophila,,ATCC 19061,,flies,7227,Drosophila melanogaster (related: fruit fly),,,,adult,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: downregulation,,,YVS,28411220,PubMed,10.1128/AEM.00185-17,Appl Environ Microbiol.2017 Apr 14. pii: AEM.00185-17,hgblair@utk.edu,The evidence suggested that the underlying cause of high-Lrp-dependent virulence attenuation in M. sexta is hypersensitivity to host immune responses and decreased insecticidal activity and that high-Lrp virulence phenotypes are insect-host specific.,Á M C Torres 2017,2017,1 gene,Casanova-Torres-2017-The global transcription,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9395,PHI:7129,UniProt,G2X9W2,GenBank,EGY15993,,,VdLs.17,VdSCP7,,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3634,Gossypium barbadense (related: sea-island cotton),,,,leaf; root,effector protein,,,salicylic acid and jasmonate signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28407259,PubMed,10.1111/nph.14537,New Phytol. 2017 Apr 13,huacl@im.ac.cn,Knockout of the VdSCP7 gene significantly enhanced V.dahliae aggressiveness on cotton.,L Zhang 2017,2017,1 gene,Zhang-2017-The Verticillium-specific protein V,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9396,PHI:7130,UniProt,P64281,GenBank,AAL22169,,,LT2; SGSC 1412; ATCC 700720,greA,,,,,,PHI:7131,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SV5015,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transcription elongation factor,,,regulatory pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28426789,PubMed,10.1371/journal.ppat.1006312,PLoS Pathog. 2017 Apr 20;13(4):e1006312,cbalsalobre@ub.edu,Invasion of HT-29 epithelial cell line was abolished in double mutant strains lacking both GreA and GreB.,T G Cantin 2017,2017,2 genes,Gaviria-Cantin-2017-Gre factors-mediated contr,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9397,PHI:7131,UniProt,Q8ZLJ2,GenBank,AAL22365,,,LT2; SGSC 1412; ATCC 700720,greB,,,,,,PHI:7130,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SV5015,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transcription elongation factor,,,regulatory pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28426789,PubMed,10.1371/journal.ppat.1006312,PLoS Pathog. 2017 Apr 20;13(4):e1006312,cbalsalobre@ub.edu,Invasion of HT-29 epithelial cell line was abolished in double mutant strains lacking both GreA and GreB.,T G Cantin 2017,2017,2 genes,Gaviria-Cantin-2017-Gre factors-mediated contr,BATCH_068A,2017-05-01,MC,,,,,,,,,,,,,
,,Record 9398,PHI:7132,UniProt,H1ZWZ1,GenBank,CBZ39993,,,NCPPB 3335,HopAO1,,,,,,,29438,Pseudomonas savastanoi,693985,pv. savastanoi strain NCPPB3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,leaf,type III effector tyrosine phosphatase,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28529516,PubMed,10.3389/fpls.2017.00680,FrontPlantSci.2017 May 5;8:680,emilia.lopez@upm.es,"A ΔhopAO1mutant ofP.savastanoiNCPBB3335exhibits a reduced fitness and virulence in olive plants, which supports the relevance of thiseffectorduring the interaction of this strain with its host plants.",M P Castañeda-Ojeda 2017,2017,1 gene,Castaneda-Ojeda-2017-Suppression of Plant Immu,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9399,PHI:7133,UniProt,G4N8I6,GenBank,EHA54263,,,70-15,MoRab5A,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,vacuolar protein sorting-associated protein,,,,reduced virulence,yes,,,yes,,reduced,reduced,,,no,calcofluor white,calcofluor white: CHEBI:50011,,,,,gene mutation; altered gene expression / gene regulation: silencing; gene complementation,,,YVS,28529514,PubMed,10.3389/fpls.2017.00620,Front Plant Sci.2017 May 5;8:620,guangpu-li@ouhsc.edu,"It was demonstrated that both MoRab5A and MoRab5B are crucial for vegetative growth and development, conidiogenesis, melanin synthesis, vacuole fusion, endocytosis, sexual reproduction, and plant pathogenesis in M. oryzae.",C D Yang 2017,2017,2 genes,Yang-2017-Two Rab5 Homologs Are Essential for,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9400,PHI:7134,UniProt,G4MWX1,GenBank,EHA51034,,,70-15,MoRab5B,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf; root,GTP-binding protein,,,,reduced virulence,yes,,,yes,,reduced,reduced,,,no,calcofluor white,calcofluor white: CHEBI:50011,,,,,gene mutation; altered gene expression / gene regulation: silencing; gene complementation,,,YVS,28529514,PubMed,10.3389/fpls.2017.00620,Front Plant Sci.2017 May 5;8:620,guangpu-li@ouhsc.edu,"It was demonstrated that both MoRab5A and MoRab5B are crucial for vegetative growth and development, conidiogenesis, melanin synthesis, vacuole fusion, endocytosis, sexual reproduction, and plant pathogenesis in M. oryzae.",C D Yang 2017,2017,2 genes,Yang-2017-Two Rab5 Homologs Are Essential for,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9401,PHI:7135,,no data found,,,,,,PsAtg6a,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,autophagy related protein,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28500315,PubMed,10.1038/s41598-017-01988-7,Sci Rep.2017 May 12;7(1):1879,honglianli@sina.com,The reduced virulence of the PsAtg6a-silenced lines seemed attributable to the inability to produce haustoria.,L Chen 2017,2017,1 gene,Chen-2017-Network and role analysis of autopha,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9402,PHI:7136,UniProt,P0C7U7,GenBank,AAA27641,,,KIM5,lcrV,,lcrVC273A,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lymph node; spleen,virulence-associated V antigen and a cap protein of type III secretion machine,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28512097,PubMed,10.1128/mBio.00646-17,MBio.2017 May 16;8(3). pii: e00646-17,oschnee@bsd.uchicago.edu,The data indicate that a single amino acid substitution (Cys273Ala) associated with loss of LcrV glutathionylation increases the survival of bubonic plague-infected rats.,A Mitchell 2017,2017,1 gene,Mitchell-2017-Glutathionylation of Yersinia pe,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9403,PHI:7136,UniProt,P0C7U7,GenBank,AAA27641,,,KIM5,lcrV,,lcrVC273A,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10116,Rattus norvegicus (related: norway rat),,,,lymph node; spleen,virulence-associated V antigen and a cap protein of type III secretion machine,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28512097,PubMed,10.1128/mBio.00646-17,MBio.2017 May 16;8(3). pii: e00646-17,oschnee@bsd.uchicago.edu,The data indicate that a single amino acid substitution (Cys273Ala) associated with loss of LcrV glutathionylation increases the survival of bubonic plague-infected rats.,A Mitchell 2017,2017,1 gene,Mitchell-2017-Glutathionylation of Yersinia pe,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9404,PHI:7137,UniProt,Q887C0,GenBank,AAO54913,,,DC3000,HrpV,,L108A/G110A,,HrpG; HrpS,UniProt: Q887C2; GenBank: AAO54910; UniProt: Q887C7; GenBank: AAO54902,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,negative regulator of hrp expression,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28488468,PubMed,10.1094/MPMI-03-17-0073-R,Mol Plant Microbe Interact.2017 May 10,m.jovanovic@imperial.ac.uk,Mutually exclusive binding of HrpS and HrpG to the same binding site of HrpV governed a transition from negative control to activation of the HrpRS complex leading to HrpL expression and pathogenicity of Ps. syringae.,M Jovanovic 2017,2017,2 genes,Jovanovic-2017-Functional characterization of,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9405,PHI:7138,UniProt,Q887C2,GenBank,AAO54910,,,DC3000,HrpG,,L101A/L105A,,HrpV,UniProt: Q887C0; GenBank: AAO54913,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,type III secretion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28488468,PubMed,10.1094/MPMI-03-17-0073-R,Mol Plant Microbe Interact.2017 May 10,m.jovanovic@imperial.ac.uk,Mutually exclusive binding of HrpS and HrpG to the same binding site of HrpV governed a transition from negative control to activation of the HrpRS complex leading to HrpL expression and pathogenicity of Ps. syringae.,M Jovanovic 2017,2017,2 genes,Jovanovic-2017-Functional characterization of,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9406,PHI:7139,,no data found,,,,,,VdFTF1,,T-DNA mutant M06D06,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,transcription factor,,,,reduced virulence,,,,,,wild type,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28520093,PubMed,10.1111/mpp.12569,Mol Plant Pathol.2017 May 18,kvsubbarao@ucdavis.edu,"VdFTF1-deletion strains displayed normal vegetative growth, mycelial pigmentation, and conidial morphology, but exhibited significantly reduced virulence on cotton.",W Q Zhang 2017,2017,2 genes,Zhang-2017-Verticillium dahliae Transcription,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9407,PHI:7140,,no data found,,,,,,VEDA_09651,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,putative secreted CAZyme,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28520093,PubMed,10.1111/mpp.12569,Mol Plant Pathol.2017 May 18,kvsubbarao@ucdavis.edu,"VdFTF1-deletion strains displayed normal vegetative growth, mycelial pigmentation, and conidial morphology, but exhibited significantly reduced virulence on cotton.",W Q Zhang 2017,2017,2 genes,Zhang-2017-Verticillium dahliae Transcription,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9408,PHI:7141,UniProt,W7MG03,GenBank,EWG50598,,,7600,Fsr1,chromosome 1,,,FvStp1; FvCyp1; FvScp1; FvSel1,UniProt: W7MUL2; GenBank: EWG48087; UniProt: W7LLK3; GenBank: EWG36323; UniProt: W7M3S4; Gen,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,striatin,,,,reduced virulence,yes,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28467007,PubMed,10.1111/mpp.12562,Mol Plant Pathol.2017 May 3,wbshim@tamu.edu,"The study suggested that FvCyp1, FvScp1 and FvSel1 were necessary for proper localization of Fsr1 to ER in F. verticillioides and perhaps for functional organization of STRIPAK complex.",H Zhang 2017,2017,7 genes,"Zhang-2017-Fsr1, a striatin homolog, forms an",BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9409,PHI:7142,UniProt,W7MUL2,GenBank,EWG48087,,,7600,FvStp1,chromosome 3,,,Fsr1,UniProt: W7MG03; GenBank: EWG50598,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,component of striatin-interacting phosphatase and kinase complex,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28467007,PubMed,10.1111/mpp.12562,Mol Plant Pathol.2017 May 3,wbshim@tamu.edu,"The study suggested that FvCyp1, FvScp1 and FvSel1 were necessary for proper localization of Fsr1 to ER in F. verticillioides and perhaps for functional organization of STRIPAK complex.",H Zhang 2017,2017,7 genes,"Zhang-2017-Fsr1, a striatin homolog, forms an",BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9410,PHI:7143,UniProt,W7LLK3,GenBank,EWG36323,,,7600,FvCYP1,chromosome 1,,,Fsr1,UniProt: W7MG03; GenBank: EWG50598,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,peptidyl-prolyl cis-trans isomerase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28467007,PubMed,10.1111/mpp.12562,Mol Plant Pathol.2017 May 3,wbshim@tamu.edu,"The study suggested that FvCyp1, FvScp1 and FvSel1 were necessary for proper localization of Fsr1 to ER in F. verticillioides and perhaps for functional organization of STRIPAK complex.",H Zhang 2017,2017,7 genes,"Zhang-2017-Fsr1, a striatin homolog, forms an",BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9411,PHI:7144,UniProt,W7M3S4,GenBank,EWG42195,,,7600,FvSCP1,chromosome 2,,,Fsr1,UniProt: W7MG03; GenBank: EWG50598,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,SCP-like extracellular protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28467007,PubMed,10.1111/mpp.12562,Mol Plant Pathol.2017 May 3,wbshim@tamu.edu,"The study suggested that FvCyp1, FvScp1 and FvSel1 were necessary for proper localization of Fsr1 to ER in F. verticillioides and perhaps for functional organization of STRIPAK complex.",H Zhang 2017,2017,7 genes,"Zhang-2017-Fsr1, a striatin homolog, forms an",BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9412,PHI:7145,UniProt,W7N0U7,GenBank,EWG53774,,,7600,FvSEL1,chromosome 4,,,Fsr1,UniProt: W7MG03; GenBank: EWG50598,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,Sel1-repeat protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28467007,PubMed,10.1111/mpp.12562,Mol Plant Pathol.2017 May 3,wbshim@tamu.edu,"The study suggested that FvCyp1, FvScp1 and FvSel1 were necessary for proper localization of Fsr1 to ER in F. verticillioides and perhaps for functional organization of STRIPAK complex.",H Zhang 2017,2017,7 genes,"Zhang-2017-Fsr1, a striatin homolog, forms an",BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9413,PHI:7146,UniProt,W7LTJ2,GenBank,EWG38795,,,7600,FvHEX1,chromosome 6,,,Fsr1,UniProt: W7MG03; GenBank: EWG50598,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,Hex1-like protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28467007,PubMed,10.1111/mpp.12562,Mol Plant Pathol.2017 May 3,wbshim@tamu.edu,"The study suggested that FvCyp1, FvScp1 and FvSel1 were necessary for proper localization of Fsr1 to ER in F. verticillioides and perhaps for functional organization of STRIPAK complex.",H Zhang 2017,2017,7 genes,"Zhang-2017-Fsr1, a striatin homolog, forms an",BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9414,PHI:7147,UniProt,W7MNK7,GenBank,EWG52656,,,7600,FvPEX14,chromosome 9,,,Fsr1,UniProt: W7MG03; GenBank: EWG50598,,117187,Fusarium verticillioides,334819,7600,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem,peroxisomal membrane anchor protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28467007,PubMed,10.1111/mpp.12562,Mol Plant Pathol.2017 May 3,wbshim@tamu.edu,"The study suggested that FvCyp1, FvScp1 and FvSel1 were necessary for proper localization of Fsr1 to ER in F. verticillioides and perhaps for functional organization of STRIPAK complex.",H Zhang 2017,2017,7 genes,"Zhang-2017-Fsr1, a striatin homolog, forms an",BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9415,PHI:7148,UniProt,A6V3V7,GenBank,ABR85931,,,PA7,pumA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,TIR effector,,,TLR signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28483816,PubMed,10.15252/embj.201695343,EMBO J.2017 May 8. pii: e201695343,suzana.salcedo@ibcp.fr,PumA is required for Pseudomonas aeruginosa PA7 virulence in vivo.,P R C Imbert 2017,2017,1 gene,Imbert-2017-A Pseudomonas aeruginosa TIR effec,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9416,PHI:7148,UniProt,A6V3V7,GenBank,ABR85931,,,PA7,pumA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),B6;129S7-Dbh<tm1Rpa>/Rpa,,,lung; spleen,TIR effector,,,TLR signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28483816,PubMed,10.15252/embj.201695343,EMBO J.2017 May 8. pii: e201695343,suzana.salcedo@ibcp.fr,PumA is required for Pseudomonas aeruginosa PA7 virulence in vivo.,P R C Imbert 2017,2017,1 gene,Imbert-2017-A Pseudomonas aeruginosa TIR effec,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9417,PHI:7149,UniProt,G4MSK7,GenBank,EHA54623,,,70-15,Moglo3,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf,ARF GTPase-activating protein,,,unfolded protein response (UPR) pathway,reduced virulence,no,no,yes,yes,,reduced,reduced,reduced,reduced,no,dithiothreitol (DTT); calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28504350,PubMed,10.1111/1462-2920.13798,Environ Microbiol. 2017 May 15,zhgzhang@njau.edu.cn,"Three domain-deleted strains (deltaGAP, deltaBoCCS, deltaGRM) of Moglo3 showed decreased pathogenicity. The deltaGAP mutant strain showed very few lesions, similar to the deltaMoglo3 mutant, whereas the deltaBoCCS and deltaGRM strains caused more lesions on sprayed/injected rice and caused expanded injuries on detached barley.",S Zhang 2017,2017,1 gene,Zhang-2017-The ArfGAP protein MoGlo3 regulates,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9418,PHI:7149,UniProt,G4MSK7,GenBank,EHA54623,,,70-15,Moglo3,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ARF GTPase-activating protein,,,unfolded protein response (UPR) pathway,reduced virulence,no,no,yes,yes,,reduced,reduced,reduced,reduced,no,dithiothreitol (DTT); calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28504350,PubMed,10.1111/1462-2920.13798,Environ Microbiol. 2017 May 15,zhgzhang@njau.edu.cn,"Three domain-deleted strains (deltaGAP, deltaBoCCS, deltaGRM) of Moglo3 showed decreased pathogenicity. The deltaGAP mutant strain showed very few lesions, similar to the deltaMoglo3 mutant, whereas the deltaBoCCS and deltaGRM strains caused more lesions on sprayed/injected rice and caused expanded injuries on detached barley.",S Zhang 2017,2017,1 gene,Zhang-2017-The ArfGAP protein MoGlo3 regulates,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9419,PHI:7150,UniProt,J4VXB0,GenBank,EJP63025,,,ARSEF 2860,eca1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,calcium transporting ATPase,,,calcineurin pathway,reduced virulence,,,,,,reduced,,reduced,reduced,no,H2O2; menadione; congo red; SDS; CaCl2; ZnCl2; MnCl2; CuCl2; FeCl3; EDTA; dithiothreitol; tunicamycin; cyclosporin A,H2O2: CHEBI:16240; menadione: CHEBI:28869; congo red: CHEBI:34653; SDS: CHEBI:8984; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976; MnCl2: CHEBI:63041; CuCl2: CHEBI:49553; FeCl3: CHEBI:30808; EDTA: CHEBI:64758; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699; cyclosporin A: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,28469160,PubMed,10.1038/s41598-017-01570-1,Sci Rep. 2017 May 3;7(1):1420,yingsh@zju.edu.cn,"All deletion mutants showed differential defects in conidial germination, vegetative growth, conidiation capacity, antioxidant activity, cell wall integrity, conidial UV-B resistance and/or virulence.",J Wang 2017,2017,6 genes,Wang-2017-Differential Roles for Six P-Type Ca,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9420,PHI:7151,UniProt,J5K3K8,GenBank,EJP70918,,,ARSEF 2860,pmcA,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,calcium transporting ATPase,,,calcineurin pathway,reduced virulence,,,,,,reduced,,wild type,reduced,no,H2O2; menadione; congo red; SDS; CaCl2; ZnCl2; MnCl2; CuCl2; FeCl3; EDTA; dithiothreitol; tunicamycin; cyclosporin A,H2O2: CHEBI:16240; menadione: CHEBI:28869; congo red: CHEBI:34653; SDS: CHEBI:8984; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976; MnCl2: CHEBI:63041; CuCl2: CHEBI:49553; FeCl3: CHEBI:30808; EDTA: CHEBI:64758; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699; cyclosporin A: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,28469160,PubMed,10.1038/s41598-017-01570-1,Sci Rep. 2017 May 3;7(1):1420,yingsh@zju.edu.cn,"All deletion mutants showed differential defects in conidial germination, vegetative growth, conidiation capacity, antioxidant activity, cell wall integrity, conidial UV-B resistance and/or virulence.",J Wang 2017,2017,6 genes,Wang-2017-Differential Roles for Six P-Type Ca,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9421,PHI:7152,UniProt,J4KMX0,GenBank,EJP64689,,,ARSEF 2860,pmcB,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,calcium transporting ATPase,,,calcineurin pathway,reduced virulence,,,,,,reduced,,reduced,reduced,no,H2O2; menadione; congo red; SDS; CaCl2; ZnCl2; MnCl2; CuCl2; FeCl3; EDTA; dithiothreitol; tunicamycin; cyclosporin A,H2O2: CHEBI:16240; menadione: CHEBI:28869; congo red: CHEBI:34653; SDS: CHEBI:8984; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976; MnCl2: CHEBI:63041; CuCl2: CHEBI:49553; FeCl3: CHEBI:30808; EDTA: CHEBI:64758; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699; cyclosporin A: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,28469160,PubMed,10.1038/s41598-017-01570-1,Sci Rep. 2017 May 3;7(1):1420,yingsh@zju.edu.cn,"All deletion mutants showed differential defects in conidial germination, vegetative growth, conidiation capacity, antioxidant activity, cell wall integrity, conidial UV-B resistance and/or virulence.",J Wang 2017,2017,6 genes,Wang-2017-Differential Roles for Six P-Type Ca,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9422,PHI:7153,UniProt,J5JIF8,GenBank,EJP63186,,,ARSEF 2860,pmcC,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,calcium transporting ATPase,,,calcineurin pathway,reduced virulence,,,,,,reduced,,wild type,reduced,no,H2O2; menadione; congo red; SDS; CaCl2; ZnCl2; MnCl2; CuCl2; FeCl3; EDTA; dithiothreitol; tunicamycin; cyclosporin A,H2O2: CHEBI:16240; menadione: CHEBI:28869; congo red: CHEBI:34653; SDS: CHEBI:8984; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976; MnCl2: CHEBI:63041; CuCl2: CHEBI:49553; FeCl3: CHEBI:30808; EDTA: CHEBI:64758; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699; cyclosporin A: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,28469160,PubMed,10.1038/s41598-017-01570-1,Sci Rep. 2017 May 3;7(1):1420,yingsh@zju.edu.cn,"All deletion mutants showed differential defects in conidial germination, vegetative growth, conidiation capacity, antioxidant activity, cell wall integrity, conidial UV-B resistance and/or virulence.",J Wang 2017,2017,6 genes,Wang-2017-Differential Roles for Six P-Type Ca,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9423,PHI:7154,UniProt,J5JJ15,GenBank,EJP65528,,,ARSEF 2860,spf1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cation-transporting P-type ATPase,,,calcineurin pathway,reduced virulence,,,,,,reduced,,reduced,reduced,no,H2O2; menadione; congo red; SDS; CaCl2; ZnCl2; MnCl2; CuCl2; FeCl3; EDTA; dithiothreitol; tunicamycin; cyclosporin A,H2O2: CHEBI:16240; menadione: CHEBI:28869; congo red: CHEBI:34653; SDS: CHEBI:8984; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976; MnCl2: CHEBI:63041; CuCl2: CHEBI:49553; FeCl3: CHEBI:30808; EDTA: CHEBI:64758; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699; cyclosporin A: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,28469160,PubMed,10.1038/s41598-017-01570-1,Sci Rep. 2017 May 3;7(1):1420,yingsh@zju.edu.cn,"All deletion mutants showed differential defects in conidial germination, vegetative growth, conidiation capacity, antioxidant activity, cell wall integrity, conidial UV-B resistance and/or virulence.",J Wang 2017,2017,6 genes,Wang-2017-Differential Roles for Six P-Type Ca,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9424,PHI:7155,UniProt,J4KLZ9,GenBank,EJP63084,,,ARSEF 2860,pmr1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,calcium-transporting P-type ATPase,,,calcineurin pathway,reduced virulence,,,,,,reduced,,reduced,reduced,no,H2O2; menadione; congo red; SDS; CaCl2; ZnCl2; MnCl2; CuCl2; FeCl3; EDTA; dithiothreitol; tunicamycin; cyclosporin A,H2O2: CHEBI:16240; menadione: CHEBI:28869; congo red: CHEBI:34653; SDS: CHEBI:8984; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976; MnCl2: CHEBI:63041; CuCl2: CHEBI:49553; FeCl3: CHEBI:30808; EDTA: CHEBI:64758; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699; cyclosporin A: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,28469160,PubMed,10.1038/s41598-017-01570-1,Sci Rep. 2017 May 3;7(1):1420,yingsh@zju.edu.cn,"All deletion mutants showed differential defects in conidial germination, vegetative growth, conidiation capacity, antioxidant activity, cell wall integrity, conidial UV-B resistance and/or virulence.",J Wang 2017,2017,6 genes,Wang-2017-Differential Roles for Six P-Type Ca,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9425,PHI:7156,,no data found,,,,,,EsxX,,,,,,,1280,Staphylococcus aureus,523796,ST398,skin infection; blood infection; pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin; kidney; blood,secreted protein,,,ESAT-6 secretion pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28529509,PubMed,10.3389/fmicb.2017.00819,Front Microbiol. 2017 May 5;8:819,ruth_limin@126.com,An esxX deletion mutant led to significantly reduced resistance to neutrophil killing and decreased virulence in murine skin and blood infection models.,Y Dai 2017,2017,1 gene,Dai-2017-A Novel ESAT-6 Secretion System-Secre,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9426,PHI:7157,UniProt,K9FNC7,GenBank,EKV04258,,,PHI26,PdsreA,,,,,,,36651,Penicillium digitatum,,PdW03,green mold (Citrus),eudicots,55188,Citrus unshiu (related: satsuma mandarin),,,,fruit,sterol regulatory element binding protein transcription factor,,,ergosterol biosynthesis pathway,unaffected pathogenicity,,,,,,,,wild type,,no,"menadione; CoCl2; diethyl maleate; H2O2; NaNO2; 2,2'-bipyridine","menadione: CHEBI:28869; CoCl2: CHEBI:35696; diethyl maleate: CHEBI:68508; H2O2: CHEBI:16240; NaNO2: CHEBI:78870; 2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,28467453,PubMed,10.1371/journal.pone.0176485,PLoS One. 2017 May 3;12(5):e0176485,hyli@zju.edu.cn,"Although the size of maceration lesions induced by the wild-type and the SREBP mutants were similar, mycelial growth of the deltaPdsreA on the surface of affected citrus fruits was retarded compared with that of the wildtype strains, while the deltaPdsreB and deltadeltaPdsreAB strains apparently failed to produce aerial mycelia on affected fruits.",R Ruan 2017,2017,2 genes,Ruan-2017-Functional analysis of two sterol re,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9427,PHI:7158,UniProt,K9G6V1,GenBank,EKV08916,,,PHI26,PdsreB,,,,,,,36651,Penicillium digitatum,,PdW03,green mold (Citrus),eudicots,55188,Citrus unshiu (related: satsuma mandarin),,,,fruit,sterol regulatory element binding protein transcription factor,,,ergosterol biosynthesis pathway,unaffected pathogenicity,,,,,,,,wild type,,no,"menadione; CoCl2; diethyl maleate; H2O2; NaNO2; 2,2'-bipyridine","menadione: CHEBI:28869; CoCl2: CHEBI:35696; diethyl maleate: CHEBI:68508; H2O2: CHEBI:16240; NaNO2: CHEBI:78870; 2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,28467453,PubMed,10.1371/journal.pone.0176485,PLoS One. 2017 May 3;12(5):e0176485,hyli@zju.edu.cn,"Although the size of maceration lesions induced by the wild-type and the SREBP mutants were similar, mycelial growth of the deltaPdsreA on the surface of affected citrus fruits was retarded compared with that of the wildtype strains, while the deltaPdsreB and deltadeltaPdsreAB strains apparently failed to produce aerial mycelia on affected fruits.",R Ruan 2017,2017,2 genes,Ruan-2017-Functional analysis of two sterol re,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9428,PHI:7157,UniProt,K9FNC7,GenBank,EKV04258,,,PHI26,PdsreA,,,,,,PHI:7158,36651,Penicillium digitatum,,PdW03,green mold (Citrus),eudicots,55188,Citrus unshiu (related: satsuma mandarin),,,,fruit,sterol regulatory element binding protein transcription factor,,,ergosterol biosynthesis pathway,unaffected pathogenicity,,,,,,,,wild type,,no,"menadione; CoCl2; diethyl maleate; H2O2; NaNO2; 2,2'-bipyridine","menadione: CHEBI:28869; CoCl2: CHEBI:35696; diethyl maleate: CHEBI:68508; H2O2: CHEBI:16240; NaNO2: CHEBI:78870; 2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full,,,YVS,28467453,PubMed,10.1371/journal.pone.0176485,PLoS One. 2017 May 3;12(5):e0176485,hyli@zju.edu.cn,"Although the size of maceration lesions induced by the wild-type and the SREBP mutants were similar, mycelial growth of the deltaPdsreA on the surface of affected citrus fruits was retarded compared with that of the wildtype strains, while the deltaPdsreB and deltadeltaPdsreAB strains apparently failed to produce aerial mycelia on affected fruits.",R Ruan 2017,2017,2 genes,Ruan-2017-Functional analysis of two sterol re,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9429,PHI:7158,UniProt,K9G6V1,GenBank,EKV08916,,,PHI26,PdsreB,,,,,,PHI:7157,36651,Penicillium digitatum,,PdW03,green mold (Citrus),eudicots,55188,Citrus unshiu (related: satsuma mandarin),,,,fruit,sterol regulatory element binding protein transcription factor,,,ergosterol biosynthesis pathway,unaffected pathogenicity,,,,,,,,wild type,,no,"menadione; CoCl2; diethyl maleate; H2O2; NaNO2; 2,2'-bipyridine","menadione: CHEBI:28869; CoCl2: CHEBI:35696; diethyl maleate: CHEBI:68508; H2O2: CHEBI:16240; NaNO2: CHEBI:78870; 2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full,,,YVS,28467453,PubMed,10.1371/journal.pone.0176485,PLoS One. 2017 May 3;12(5):e0176485,hyli@zju.edu.cn,"Although the size of maceration lesions induced by the wild-type and the SREBP mutants were similar, mycelial growth of the deltaPdsreA on the surface of affected citrus fruits was retarded compared with that of the wildtype strains, while the deltaPdsreB and deltadeltaPdsreAB strains apparently failed to produce aerial mycelia on affected fruits.",R Ruan 2017,2017,2 genes,Ruan-2017-Functional analysis of two sterol re,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9430,PHI:7159,UniProt,A6RSE2,GenBank,XP_001558137,,,B05.10,bcelp4,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,elongator complex protein 4,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl; KCl; H2O2; caffeine; congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; caffeine: CHEBI:27732; congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,28474462,PubMed,10.1111/1751-7915.12720,Microb Biotechnol. 2017 May 5,changjun-chen@njau.edu.cn,"The wild-type strain and the complemented strain produced vast sclerotia, while the bcelp4 mutant lost the ability of sclerotia formation. This result indicated that the bcelp4 played an important role in sexual reproduction mechanism in B. cinerea.",W Shao 2017,2017,1 gene,Shao-2017-Involvement of BcElp4 in vegetative,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9431,PHI:7159,UniProt,A6RSE2,GenBank,XP_001558137,,,B05.10,bcelp4,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,elongator complex protein 4,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl; KCl; H2O2; caffeine; congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; caffeine: CHEBI:27732; congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,28474462,PubMed,10.1111/1751-7915.12720,Microb Biotechnol. 2017 May 5,changjun-chen@njau.edu.cn,"The wild-type strain and the complemented strain produced vast sclerotia, while the bcelp4 mutant lost the ability of sclerotia formation. This result indicated that the bcelp4 played an important role in sexual reproduction mechanism in B. cinerea.",W Shao 2017,2017,1 gene,Shao-2017-Involvement of BcElp4 in vegetative,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9432,PHI:7159,UniProt,A6RSE2,GenBank,XP_001558137,,,B05.10,bcelp4,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,elongator complex protein 4,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl; KCl; H2O2; caffeine; congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; caffeine: CHEBI:27732; congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,28474462,PubMed,10.1111/1751-7915.12720,Microb Biotechnol. 2017 May 5,changjun-chen@njau.edu.cn,"The wild-type strain and the complemented strain produced vast sclerotia, while the bcelp4 mutant lost the ability of sclerotia formation. This result indicated that the bcelp4 played an important role in sexual reproduction mechanism in B. cinerea.",W Shao 2017,2017,1 gene,Shao-2017-Involvement of BcElp4 in vegetative,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9433,PHI:7159,UniProt,A6RSE2,GenBank,XP_001558137,,,B05.10,bcelp4,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,elongator complex protein 4,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl; KCl; H2O2; caffeine; congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; caffeine: CHEBI:27732; congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,28474462,PubMed,10.1111/1751-7915.12720,Microb Biotechnol. 2017 May 5,changjun-chen@njau.edu.cn,"The wild-type strain and the complemented strain produced vast sclerotia, while the bcelp4 mutant lost the ability of sclerotia formation. This result indicated that the bcelp4 played an important role in sexual reproduction mechanism in B. cinerea.",W Shao 2017,2017,1 gene,Shao-2017-Involvement of BcElp4 in vegetative,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9434,PHI:7160,UniProt,D4HY24,GenBank,CBJ45669,,,ATCC 49946,lon,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28509355,PubMed,10.1111/mpp.12566,Mol Plant Pathol. 2017 May 16,zhao888@illinois.edu,"Lon suppressed expression of genes required for T3SS and amylovoran in E. amylovora, but was not indispensable for its virulence.",J H Lee 2017,2017,2 genes,Lee-2017-Lon protease modulates virulence trai,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9435,PHI:7161,UniProt,D4HX67,GenBank,CBA19758,,,CFPB1430,csrA,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,RNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28509355,PubMed,10.1111/mpp.12566,Mol Plant Pathol. 2017 May 16,zhao888@illinois.edu,"Lon suppressed expression of genes required for T3SS and amylovoran in E. amylovora, but was not indispensable for its virulence.",J H Lee 2017,2017,2 genes,Lee-2017-Lon protease modulates virulence trai,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9436,PHI:7160,UniProt,D4HY24,GenBank,CBJ45669,,,ATCC 49946,lon,,,,,,PHI:7161,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,protease,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28509355,PubMed,10.1111/mpp.12566,Mol Plant Pathol. 2017 May 16,zhao888@illinois.edu,"Lon suppressed expression of genes required for T3SS and amylovoran in E. amylovora, but was not indispensable for its virulence.",J H Lee 2017,2017,2 genes,Lee-2017-Lon protease modulates virulence trai,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9437,PHI:7161,UniProt,D4HX67,GenBank,CBA19758,,,CFPB1430,csrA,,,,,,PHI:7160,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,RNA-binding protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28509355,PubMed,10.1111/mpp.12566,Mol Plant Pathol. 2017 May 16,zhao888@illinois.edu,"Lon suppressed expression of genes required for T3SS and amylovoran in E. amylovora, but was not indispensable for its virulence.",J H Lee 2017,2017,2 genes,Lee-2017-Lon protease modulates virulence trai,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9438,PHI:7162,UniProt,O87002,GenBank,AAC23932,,,PAO1,chpB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,corneal infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,cornea,protein-glutamate methylesterase,,,Pil-Chp pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28489917,PubMed,10.1371/journal.ppat.1006392,PLoS Pathog. 2017 May 10;13(5):e1006392,fleiszig@berkeley.edu,"Host gene data available for DMBT1 . DMBT1 suppressed twitching motility of P. aeruginosa chemotaxis mutants (chpB, pilK), and an adenylate cyclase mutant (cyaB) suggesting that those genes are not needed for DMBT1-mediated twitching inhibition.",J Li 2017,2017,3 genes,Li-2017-Mucosal fluid glycoprotein DMBT1 suppr,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9439,PHI:7163,UniProt,Q51346,GenBank,CRQ82845,,,E15_London_28_01_14,pilK,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,corneal infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,cornea,chemotaxis protein methyltransferase,,,Pil-Chp pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28489917,PubMed,10.1371/journal.ppat.1006392,PLoS Pathog. 2017 May 10;13(5):e1006392,fleiszig@berkeley.edu,"Host gene data available for DMBT1 . DMBT1 suppressed twitching motility of P. aeruginosa chemotaxis mutants (chpB, pilK), and an adenylate cyclase mutant (cyaB) suggesting that those genes are not needed for DMBT1-mediated twitching inhibition.",J Li 2017,2017,3 genes,Li-2017-Mucosal fluid glycoprotein DMBT1 suppr,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9440,PHI:7164,UniProt,Q9HZ23,GenBank,AE004745_2,,,PAO1,cyaB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,corneal infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,cornea,adenylate cyclase,,,Pil-Chp pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28489917,PubMed,10.1371/journal.ppat.1006392,PLoS Pathog. 2017 May 10;13(5):e1006392,fleiszig@berkeley.edu,"Host gene data available for DMBT1 . DMBT1 suppressed twitching motility of P. aeruginosa chemotaxis mutants (chpB, pilK), and an adenylate cyclase mutant (cyaB) suggesting that those genes are not needed for DMBT1-mediated twitching inhibition.",J Li 2017,2017,3 genes,Li-2017-Mucosal fluid glycoprotein DMBT1 suppr,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9441,PHI:7165,UniProt,Q4WN33,GenBank,EAL88631,,,Af293,AceA,chromosome 6,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,putative copper-binding transcription factor,,,ROI-generating pathway,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,28467895,PubMed,10.1016/j.celrep.2017.04.019,Cell Rep. 2017 May 2;19(5):1008-1021,nosherov@post.tau.ac.il,ΔAceA survival is remediated by dampening of host ROI (chemically or genetically) or enhancement of copper-exporting activity (CrpA) in A. fumigatus.,P Wiemann 2017,2017,4 genes,Wiemann-2017-Aspergillus fumigatus Copper Expo,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9442,PHI:7166,UniProt,Q4WSD1,GenBank,EAL90651,,,Af293,macA,chromosome 1,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,copper-starvation TF,,,ROI-generating pathway,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,28467895,PubMed,10.1016/j.celrep.2017.04.019,Cell Rep. 2017 May 2;19(5):1008-1021,nosherov@post.tau.ac.il,ΔAceA survival is remediated by dampening of host ROI (chemically or genetically) or enhancement of copper-exporting activity (CrpA) in A. fumigatus.,P Wiemann 2017,2017,4 genes,Wiemann-2017-Aspergillus fumigatus Copper Expo,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9443,PHI:7167,UniProt,Q4WIN8,GenBank,EAL87217,,,Af293,cufA,chromosome 2,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,copper-binding TF with specialized function,,,ROI-generating pathway,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,28467895,PubMed,10.1016/j.celrep.2017.04.019,Cell Rep. 2017 May 2;19(5):1008-1021,nosherov@post.tau.ac.il,ΔAceA survival is remediated by dampening of host ROI (chemically or genetically) or enhancement of copper-exporting activity (CrpA) in A. fumigatus.,P Wiemann 2017,2017,4 genes,Wiemann-2017-Aspergillus fumigatus Copper Expo,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9444,PHI:7168,UniProt,Q4WYE4,GenBank,EAL92309,,,Af293,crpA,chromosome 3,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,copper-exporting ATPase,,,ROI-generating pathway,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,28467895,PubMed,10.1016/j.celrep.2017.04.019,Cell Rep. 2017 May 2;19(5):1008-1021,nosherov@post.tau.ac.il,ΔAceA survival is remediated by dampening of host ROI (chemically or genetically) or enhancement of copper-exporting activity (CrpA) in A. fumigatus.,P Wiemann 2017,2017,4 genes,Wiemann-2017-Aspergillus fumigatus Copper Expo,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9445,PHI:7165,UniProt,Q4WN33,GenBank,EAL88631,,,Af293,AceA,chromosome 6,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),Hsd:ICR,,,lung,putative copper-binding transcription factor,,,ROI-generating pathway,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,28467895,PubMed,10.1016/j.celrep.2017.04.019,Cell Rep. 2017 May 2;19(5):1008-1021,nosherov@post.tau.ac.il,ΔAceA survival is remediated by dampening of host ROI (chemically or genetically) or enhancement of copper-exporting activity (CrpA) in A. fumigatus.,P Wiemann 2017,2017,4 genes,Wiemann-2017-Aspergillus fumigatus Copper Expo,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9446,PHI:7166,UniProt,Q4WSD1,GenBank,EAL90651,,,Af293,macA,chromosome 1,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),Hsd:ICR,,,lung,copper-starvation TF,,,ROI-generating pathway,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,28467895,PubMed,10.1016/j.celrep.2017.04.019,Cell Rep. 2017 May 2;19(5):1008-1021,nosherov@post.tau.ac.il,ΔAceA survival is remediated by dampening of host ROI (chemically or genetically) or enhancement of copper-exporting activity (CrpA) in A. fumigatus.,P Wiemann 2017,2017,4 genes,Wiemann-2017-Aspergillus fumigatus Copper Expo,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9447,PHI:7167,UniProt,Q4WIN8,GenBank,EAL87217,,,Af293,cufA,chromosome 2,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),Hsd:ICR,,,lung,copper-binding TF with specialized function,,,ROI-generating pathway,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,28467895,PubMed,10.1016/j.celrep.2017.04.019,Cell Rep. 2017 May 2;19(5):1008-1021,nosherov@post.tau.ac.il,ΔAceA survival is remediated by dampening of host ROI (chemically or genetically) or enhancement of copper-exporting activity (CrpA) in A. fumigatus.,P Wiemann 2017,2017,4 genes,Wiemann-2017-Aspergillus fumigatus Copper Expo,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9448,PHI:7168,UniProt,Q4WYE4,GenBank,EAL92309,,,Af293,crpA,chromosome 3,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),Hsd:ICR,,,lung,copper-exporting ATPase,,,ROI-generating pathway,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,28467895,PubMed,10.1016/j.celrep.2017.04.019,Cell Rep. 2017 May 2;19(5):1008-1021,nosherov@post.tau.ac.il,ΔAceA survival is remediated by dampening of host ROI (chemically or genetically) or enhancement of copper-exporting activity (CrpA) in A. fumigatus.,P Wiemann 2017,2017,4 genes,Wiemann-2017-Aspergillus fumigatus Copper Expo,BATCH_069,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9449,PHI:7169,UniProt,B8ZKB0,GenBank,SPN23F01520,,,,Vp1,,,,,,,1313,Streptococcus pneumoniae,,PN4595-T23,otitis media,rodents,34839,Chinchilla lanigera (related: long-tailed chinchilla),,,,brain; lung,secreted Gly-Gly peptide,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28557053,PubMed,10.1111/mmi.13721,Mol Microbiol.2017 May 29,lhiller@andrew.cmu.edu,The wild-type biofilm is restored with the exogenous addition of synthetic VP1.,R A Cuevas 2017,2017,1 gene,Cuevas-2017-A novel streptococcal cell-cell co,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9450,PHI:7170,,no data found,,,,,,RaxX,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Taipei 309,,,leaf,virulence-associated sulfated peptide,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28556915,PubMed,10.1111/nph.14609,New Phytol.2017 Jul;215(2):725-736,pcronald@ucdavis.edu,"Xanthomonas strain lacking raxX is impaired in its ability to infect rice lacking XA21, suggesting that RaxX is a virulence factor.",R N Pruitt 2017,2017,2 genes,Pruitt-2017-A microbially derived tyrosine-sul,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9451,PHI:7171,UniProt,Q8KWX0,GenBank,AF389909_1,,,,RaxST,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Taipei 309,,,leaf,bacterial sulfotransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28556915,PubMed,10.1111/nph.14609,New Phytol.2017 Jul;215(2):725-736,pcronald@ucdavis.edu,"Xanthomonas strain lacking raxX is impaired in its ability to infect rice lacking XA21, suggesting that RaxX is a virulence factor.",R N Pruitt 2017,2017,2 genes,Pruitt-2017-A microbially derived tyrosine-sul,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9452,PHI:7172,UniProt,G2XHI2,GenBank,EGY19276,,,VdLs.17,Clp-1,chromosome 3,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,Ca2+-dependent cysteine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27668926,PubMed,10.1038/nplants.2016.153,NatPlants.2016 Sep 26;2(10):16153,guohs@im.ac.cn,The fungal virulence genes are specifically targeted by the miRNAs exported from the infected host plants for silencing to confer resistance to the fungal pathogen.,T Zhang 2016,2016,2 genes,Zhang-2016-Cotton plants export microRNAs to i,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9453,PHI:7173,UniProt,G2XIG8,GenBank,EGY19616,,,VdLs.17,HiC-15,chromosome 1,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,isotrichodermin C-15 hydroxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27668926,PubMed,10.1038/nplants.2016.153,NatPlants.2016 Sep 26;2(10):16153,guohs@im.ac.cn,The fungal virulence genes are specifically targeted by the miRNAs exported from the infected host plants for silencing to confer resistance to the fungal pathogen.,T Zhang 2016,2016,2 genes,Zhang-2016-Cotton plants export microRNAs to i,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9454,PHI:7174,UniProt,Q9I0R8,GenBank,AAG05955,,,PAO1,PA2567,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,phosphodiesterase,,,c-diGMP signaling,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,28579350,PubMed,10.1016/j.jiac.2017.05.002,J Infect Chemother.2017 Jun 1. pii: S1341-321X(17)30108-3,kimsou@med.toho-u.ac.jp,"In-frame deletion of the PA2567 gene affected both virulence factors and the quorum-sensing system, and significantly decreased total bacteria in a mouse pneumonia model compared to the wild-type strain. Expression of the PA2567 gene was significantly repressed by azithromycin in a time and dose-dependent manner.",S Kimura 2017,2017,1 gene,"Kimura-2017-Azithromycin Modulates 3',5'-cycli",BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9455,PHI:7177,UniProt,Q56807,GenBank,AAB00675,,,,avrb6,,,,,,,346,Xanthomonas citri,,subsp. malvacearum strain H1005,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,TAL effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28537271,PubMed,10.1038/ncomms15588,Nat Commun.2017 May 24;8:15588,lshan@tamu.edu,"Activation of GhSWEET10 by designer TAL effectors (dTALEs) restores virulence of Xcm avrb6 deletion strains, whereas silencing of GhSWEET10 compromises cotton susceptibility to infections.",K L Cox 2017,2017,3 genes,Cox-2017-TAL effector driven induction of a SW,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9456,PHI:7178,UniProt,J9VNI6,GenBank,AFR94976,,,H99,Ape4,chromosome 5,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,aspartyl aminopeptidase,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; KCl; congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; congo red: CHEBI:34653,,,,,gene disruption; gene complementation,,,YVS,28542452,PubMed,10.1371/journal.pone.0177461,PLoS One.2017 May 25;12(5):e0177461,marcelo.vallim@unifesp.br,"C. neoformans ape4 mutant does not grow at 37°C and is more sensitive to fluconazole, implicating autophagy in antifungal tolerance.",F A Gontijo 2017,2017,1 gene,Gontijo-2017-The role of Aspartyl aminopeptida,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9457,PHI:7179,UniProt,Q46962,GenBank,AAA85196,,,A70.1,CNF-1,,,,,,,562,Escherichia coli,,U8,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,urinary bladder; kidney,cytotoxic necrotizing factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28545489,PubMed,10.1186/s12866-017-1036-0,BMC Microbiol.2017 May 25;17(1):127,jmichau4@jhmi.edu,"No alterations in bacterial burden with the loss of CNF1 were observed, whereas loss of the virulence factor fimH decreased bacterial burdens.",J E Michaud 2017,2017,2 genes,Michaud-2017-Cytotoxic Necrotizing Factor-1 (C,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9458,PHI:7179,UniProt,Q46962,GenBank,AAA85196,,,A70.1,CNF-1,,,,,,,562,Escherichia coli,,U8,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeOuJ,,,urinary bladder; kidney,cytotoxic necrotizing factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28545489,PubMed,10.1186/s12866-017-1036-0,BMC Microbiol.2017 May 25;17(1):127,jmichau4@jhmi.edu,"No alterations in bacterial burden with the loss of CNF1 were observed, whereas loss of the virulence factor fimH decreased bacterial burdens.",J E Michaud 2017,2017,2 genes,Michaud-2017-Cytotoxic Necrotizing Factor-1 (C,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9459,PHI:7179,UniProt,Q46962,GenBank,AAA85196,,,A70.1,CNF-1,,,,,,,562,Escherichia coli,,U8,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urinary bladder; kidney,cytotoxic necrotizing factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28545489,PubMed,10.1186/s12866-017-1036-0,BMC Microbiol.2017 May 25;17(1):127,jmichau4@jhmi.edu,"No alterations in bacterial burden with the loss of CNF1 were observed, whereas loss of the virulence factor fimH decreased bacterial burdens.",J E Michaud 2017,2017,2 genes,Michaud-2017-Cytotoxic Necrotizing Factor-1 (C,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9460,PHI:7179,UniProt,Q46962,GenBank,AAA85196,,,A70.1,CNF-1,,,,,,,562,Escherichia coli,439184,RS218,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeOuJ,,,urinary bladder; kidney,cytotoxic necrotizing factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28545489,PubMed,10.1186/s12866-017-1036-0,BMC Microbiol.2017 May 25;17(1):127,jmichau4@jhmi.edu,"No alterations in bacterial burden with the loss of CNF1 were observed, whereas loss of the virulence factor fimH decreased bacterial burdens.",J E Michaud 2017,2017,2 genes,Michaud-2017-Cytotoxic Necrotizing Factor-1 (C,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9461,PHI:7180,UniProt,P08191,GenBank,CAA29156,,,,fimH,,,,,,,562,Escherichia coli,439184,RS218,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeOuJ,,,urinary bladder; kidney,virulence factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28545489,PubMed,10.1186/s12866-017-1036-0,BMC Microbiol.2017 May 25;17(1):127,jmichau4@jhmi.edu,"No alterations in bacterial burden with the loss of CNF1 were observed, whereas loss of the virulence factor fimH decreased bacterial burdens.",J E Michaud 2017,2017,2 genes,Michaud-2017-Cytotoxic Necrotizing Factor-1 (C,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9462,PHI:7181,UniProt,J4W023,GenBank,EJP63875,,,ARSEF 2860,cypB,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,peptidyl-prolyl cis-trans isomerase-putative secretory protein,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,H2O2; Congo red; menadione; rapamycin; cyclosporin A,H2O2: CHEBI:16240; Congo red: CHEBI:34653; menadione: CHEBI:28869; rapamycin: CHEBI:9168; cyclosporin A: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,28552321,PubMed,10.1016/j.fgb.2017.05.004,Fungal Genet Biol.2017 May 25;105:8-15,mgfeng@zju.edu.cn,CypB also plays an important role in sustaining dimorphic transition and normal blastospore morphology in B. bassiana.,Z J Chu 2017,2017,1 gene,Chu-2017-Vital role for cyclophilin B (CypB) i,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9463,PHI:7182,UniProt,Q10838,GenBank,CCP44758,,,H37Rv,Rv1988,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,histone methyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,26568365,PubMed,10.1038/ncomms9922,Nat Commun.2015 Nov 16;6:8922,sanjuk@cdfd.org.in,"Rv1988 deletion in Mycobacterium tuberculosis reduces bacterial survival in the host, and experimental expression of M. tuberculosis Rv1988 in non-pathogenic Mycobacterium smegmatis negatively affects the health of infected mice.",I Yaseen 2015,2015,1 gene,Yaseen-2015-Mycobacteria modulate host epigene,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9464,PHI:7183,UniProt,Q18C12,GenBank,CAJ68357,,,630,CD1492,,,,,,,1496,Clostridioides difficile,272563,630,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,cecum,two-component sensor histidine kinase,,,,reduced virulence,,,,,,increased,,wild type,reduced,no,,,,,,,gene mutation; gene complementation,,,YVS,27647869,PubMed,10.1128/IAI.00735-16,Infect Immun.2016 Nov 18;84(12):3434-3444,shonna.mcbride@emory.edu,CD1492 negatively affects sporulation and positively influences motility and virulence. Pathogen formerly called Clostridium difficile,K O Childress 2016,2016,1 gene,Childress-2016-The Phosphotransfer Protein CD1,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9465,PHI:7184,UniProt,Q8YFR7,GenBank,AAL52634,,,16M,bpdA,chromosome I,,,,,,29459,Brucella melitensis,224914,16M,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,phosphodiesterase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27672085,PubMed,10.1128/IAI.00531-16,Infect Immun.2016 Nov 18;84(12):3458-3470,mkhan23@wisc.edu,The bpdA mutant fails to establish long-term infection in vitro and in vivo.,M Khan 2016,2016,2 genes,Khan-2016-The bacterial second messenger cycli,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9466,PHI:7185,UniProt,Q8YFK0,GenBank,AAL52701,,,16M,cgsB,chromosome I,,,,,,29459,Brucella melitensis,224914,16M,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,low cyclic-di-GMP guanylate cyclase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,27672085,PubMed,10.1128/IAI.00531-16,Infect Immun.2016 Nov 18;84(12):3458-3470,mkhan23@wisc.edu,The bpdA mutant fails to establish long-term infection in vitro and in vivo.,M Khan 2016,2016,2 genes,Khan-2016-The bacterial second messenger cycli,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9467,PHI:7186,UniProt,J9VSX1,GenBank,AFR96491,,,H99,ADE13,chromosome 8,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung; liver; spleen; kidney,bifunctional enzyme adenylosuccinate (ADS) lyase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28559277,PubMed,10.1074/jbc.M117.787994,J Biol Chem.2017 May 30. pii: jbc.M117.787994,jafraser@uq.edu.au,ΔAde13 mutant is an adenine auxotroph and was unable to successfully cause infections in a murine model of virulence.,J L Chitty 2017,2017,1 gene,Chitty-2017-Cryptococcus neoformans ADS lyase,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9468,PHI:7187,UniProt,G4N6W5,GenBank,EHA50729,,,70-15,MoCAPA,chromosome 4,,,MoArk1,UniProt: G4MV67; GenBank: EHA54082,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,F-actin capping protein homolog,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28542408,PubMed,10.1371/journal.pgen.1006814,PLoS Genet.2017 May 25;13(5):e1006814,zhgzhang@njau.edu.cn,"MoCAP proteins whose functions are regulated by MoArk1 and PIP2 are important for endocytosis and actin dynamics that are directly linked to growth, conidiation and pathogenicity of M. oryzae.",L Li 2017,2017,2 genes,Li-2017-MoCAP proteins regulated by MoArk1-med,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9469,PHI:7188,UniProt,G4MR53,GenBank,EHA57385,,,70-15,MoCAPB,chromosome 1,,,MoArk1,UniProt: G4MV67; GenBank: EHA54082,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,F-actin capping protein homolog,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28542408,PubMed,10.1371/journal.pgen.1006814,PLoS Genet.2017 May 25;13(5):e1006814,zhgzhang@njau.edu.cn,"MoCAP proteins whose functions are regulated by MoArk1 and PIP2 are important for endocytosis and actin dynamics that are directly linked to growth, conidiation and pathogenicity of M. oryzae.",L Li 2017,2017,2 genes,Li-2017-MoCAP proteins regulated by MoArk1-med,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9470,PHI:7187,UniProt,G4N6W5,GenBank,EHA50729,,,70-15,MoCAPA,chromosome 4,,,MoArk1,UniProt: G4MV67; GenBank: EHA54082,PHI:7188,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,F-actin capping protein homolog,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28542408,PubMed,10.1371/journal.pgen.1006814,PLoS Genet.2017 May 25;13(5):e1006814,zhgzhang@njau.edu.cn,"MoCAP proteins whose functions are regulated by MoArk1 and PIP2 are important for endocytosis and actin dynamics that are directly linked to growth, conidiation and pathogenicity of M. oryzae.",L Li 2017,2017,2 genes,Li-2017-MoCAP proteins regulated by MoArk1-med,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9471,PHI:7188,UniProt,G4MR53,GenBank,EHA57385,,,70-15,MoCAPB,chromosome 1,,,MoArk1,UniProt: G4MV67; GenBank: EHA54082,PHI:7187,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,F-actin capping protein homolog,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28542408,PubMed,10.1371/journal.pgen.1006814,PLoS Genet.2017 May 25;13(5):e1006814,zhgzhang@njau.edu.cn,"MoCAP proteins whose functions are regulated by MoArk1 and PIP2 are important for endocytosis and actin dynamics that are directly linked to growth, conidiation and pathogenicity of M. oryzae.",L Li 2017,2017,2 genes,Li-2017-MoCAP proteins regulated by MoArk1-med,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9472,PHI:7187,UniProt,G4N6W5,GenBank,EHA50729,,,70-15,MoCAPA,chromosome 4,,,MoArk1,UniProt: G4MV67; GenBank: EHA54082,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,F-actin capping protein homolog,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28542408,PubMed,10.1371/journal.pgen.1006814,PLoS Genet.2017 May 25;13(5):e1006814,zhgzhang@njau.edu.cn,"MoCAP proteins whose functions are regulated by MoArk1 and PIP2 are important for endocytosis and actin dynamics that are directly linked to growth, conidiation and pathogenicity of M. oryzae.",L Li 2017,2017,2 genes,Li-2017-MoCAP proteins regulated by MoArk1-med,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9473,PHI:7188,UniProt,G4MR53,GenBank,EHA57385,,,70-15,MoCAPB,chromosome 1,,,MoArk1,UniProt: G4MV67; GenBank: EHA54082,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,F-actin capping protein homolog,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28542408,PubMed,10.1371/journal.pgen.1006814,PLoS Genet.2017 May 25;13(5):e1006814,zhgzhang@njau.edu.cn,"MoCAP proteins whose functions are regulated by MoArk1 and PIP2 are important for endocytosis and actin dynamics that are directly linked to growth, conidiation and pathogenicity of M. oryzae.",L Li 2017,2017,2 genes,Li-2017-MoCAP proteins regulated by MoArk1-med,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9474,PHI:7187,UniProt,G4N6W5,GenBank,EHA50729,,,70-15,MoCAPA,chromosome 4,,,MoArk1,UniProt: G4MV67; GenBank: EHA54082,PHI:7188,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,F-actin capping protein homolog,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28542408,PubMed,10.1371/journal.pgen.1006814,PLoS Genet.2017 May 25;13(5):e1006814,zhgzhang@njau.edu.cn,"MoCAP proteins whose functions are regulated by MoArk1 and PIP2 are important for endocytosis and actin dynamics that are directly linked to growth, conidiation and pathogenicity of M. oryzae.",L Li 2017,2017,2 genes,Li-2017-MoCAP proteins regulated by MoArk1-med,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9475,PHI:7188,UniProt,G4MR53,GenBank,EHA57385,,,70-15,MoCAPB,chromosome 1,,,MoArk1,UniProt: G4MV67; GenBank: EHA54082,PHI:7187,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,F-actin capping protein homolog,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28542408,PubMed,10.1371/journal.pgen.1006814,PLoS Genet.2017 May 25;13(5):e1006814,zhgzhang@njau.edu.cn,"MoCAP proteins whose functions are regulated by MoArk1 and PIP2 are important for endocytosis and actin dynamics that are directly linked to growth, conidiation and pathogenicity of M. oryzae.",L Li 2017,2017,2 genes,Li-2017-MoCAP proteins regulated by MoArk1-med,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9476,PHI:7189,UniProt,B2HK79,GenBank,ACC43576,,,M,whiB4,,,,,,,1781,Mycobacterium marinum,1131442,E11,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,liver; kidney; intestine,iron-sulfur containing transcription factor that is highly sensitive to oxygen exposure,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28592799,PubMed,10.1038/s41598-017-03020-4,Sci Rep.2017 Jun 7;7(1):3007,jun.liu@utoronto.ca,"Several antioxidant enzymes were also upregulated in ΔwhiB4, supporting its role in modulation of oxidative stress response.",J Wu 2017,2017,1 gene,Wu-2017-WhiB4 Regulates the PE_PPE Gene Family,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9477,PHI:7190,UniProt,G2XEQ5,GenBank,EGY18306,,,VdLs.17,VDAG_08640,chromosome 2,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,seedling; root,bZiptranscriptionfactor,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28578019,PubMed,10.1016/j.gene.2017.05.061,Gene.2017 May 31. pii: S0378-1119(17)30438-9,ylwang@bjfu.edu.cn,"Compared to the single mutant and wild-type strain, the double mutant exhibited increased sensitivity to oxidative stress.",Y Fang 2017,2017,2 genes,Fang-2017-Functional characterization of two b,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9478,PHI:7191,UniProt,G2XEU1,GenBank,EGY18342,,,VdLs.17,VDAG_08676,chromosome 2,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,seedling; root,bZiptranscriptionfactor,,,,reduced virulence,,,,,,reduced,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28578019,PubMed,10.1016/j.gene.2017.05.061,Gene.2017 May 31. pii: S0378-1119(17)30438-9,ylwang@bjfu.edu.cn,"Compared to the single mutant and wild-type strain, the double mutant exhibited increased sensitivity to oxidative stress.",Y Fang 2017,2017,2 genes,Fang-2017-Functional characterization of two b,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9479,PHI:7192,UniProt,J4KLP6,GenBank,EJP62569,,,ARSEF 2860,VLP4,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,virulence related vacuole-localized protein,,,,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28557308,PubMed,10.1111/1462-2920.13803,Environ Microbiol.2017 May 30,mgfeng@zju.edu.cn,"The deletion mutant formed no autophagosome in hyphal vacuoles and displayed severe defects in aerial conidiation, conidial hydrophobicity to the insect surface, and secretion of cuticle-degrading Pr1 proteases required for normal cuticle infection.",Z J Chu 2017,2017,1 gene,Chu-2017-Discovery of a new intravacuolar prot,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9480,PHI:7193,UniProt,I1RAW4,GenBank,ESU05865,,,PH-1; NRRL 31084,FgLaeA,chromosome 1,,,FgVeA,UniProt: I1S537; GenBank: ESU06761,,5518,Fusarium graminearum,,Z-3643,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,global regulator,,,,reduced virulence,no,,,,,reduced,increased,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,23874628,PubMed,10.1371/journal.pone.0068441,PLoS One.2013 Jul 16;8(7):e68441,sy14@sch.ac.kr,"ΔFgLaeA strains exhibited an earlier induction of sexual fruiting body (perithecia) formation and drastically reduced disease symptoms in wheat, indicating that FgLaeA seems to negatively control perithecial induction, but positively control virulence toward the host plant.",H K Kim 2013,2013,1 gene,Kim-2013-Functional roles of FgLaeA in control,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9481,PHI:7194,UniProt,G5EI24,GenBank,XP_003721317,,,70-15,WISH,chromosome 7,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. HR-12,,,leaf,"transmembrane protein related to water wettability, infection, surface sensing and hyper-conidiation",,,,reduced virulence,,yes,yes,,,increased,,reduced; aberrant,wild type,no,Congo red; calcofluor white,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,28576657,PubMed,10.1016/j.fgb.2017.05.006,Fungal Genet Biol.2017 May 31;105:37-51,subhankarroy.barman@bt.nitdgp.ac.in,WISH mutants are nonpathogenic due to a defect in sensing hydrophobic surface and appressorium differentiation.,N Sabnam 2017,2017,1 gene,"Sabnam-2017-WISH, a novel CFEM GPCR is indispe",BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9482,PHI:7195,UniProt,Q5A4W8,GenBank,AOW29466,,,SC5314,Bdf1,chromosome 5,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,bromo and extra-terminal domain containing protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,28516956,PubMed,10.1038/ncomms15482,Nat Commun.2017 May 18;8:15482,carlo.petosa@ibs.fr,BET protein Bdf1 is essential in C. albicans and that mutations inactivating its two bromodomains result in a loss of viability in vitro and decreased virulence in mice.,F Mietton 2017,2017,1 gene,Mietton-2017-Selective BET bromodomain inhibit,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9483,PHI:7196,UniProt,A0A0H3PA98,,,,,,pgp1,,,,,,,197,Campylobacter jejuni,,81-176,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,dl-carboxypeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27647867,PubMed,10.1128/IAI.00751-16,Infect Immun.2016 Nov 18;84(12):3399-3407,egaynor@mail.ubc.ca,"Host gene alteration data available for SIGIRR. Despite displaying wild-type colonization of the intestinal lumen, the straight rod Δpgp1 and Δpgp2 mutants were essentially nonpathogenic, while all strains with a curved or helical shape retained their expected virulence.",M Stahl 2016,2016,3 genes,Stahl-2016-The helical shape of Campylobacter,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9484,PHI:7197,UniProt,A0A1B3X9V1,GenBank,AOH49994,,,14983A,pgp2,,,,,,,197,Campylobacter jejuni,,81-176,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,dl-carboxypeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27647867,PubMed,10.1128/IAI.00751-16,Infect Immun.2016 Nov 18;84(12):3399-3407,egaynor@mail.ubc.ca,"Host gene alteration data available for SIGIRR. Despite displaying wild-type colonization of the intestinal lumen, the straight rod Δpgp1 and Δpgp2 mutants were essentially nonpathogenic, while all strains with a curved or helical shape retained their expected virulence.",M Stahl 2016,2016,3 genes,Stahl-2016-The helical shape of Campylobacter,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9485,PHI:7198,UniProt,A0A0H3P9Y0,GenBank,EAQ72254,,,81-176,cjj81176_1228,,,,,,,197,Campylobacter jejuni,,81-176,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,dl-carboxypeptidase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,27647867,PubMed,10.1128/IAI.00751-16,Infect Immun.2016 Nov 18;84(12):3399-3407,egaynor@mail.ubc.ca,"Host gene alteration data available for SIGIRR. Despite displaying wild-type colonization of the intestinal lumen, the straight rod Δpgp1 and Δpgp2 mutants were essentially nonpathogenic, while all strains with a curved or helical shape retained their expected virulence.",M Stahl 2016,2016,3 genes,Stahl-2016-The helical shape of Campylobacter,BATCH_070A,2017-06-17,MC,,,,,,,,,,,,,
,,Record 9486,PHI:7199,,no data found,,,,,,AbcR1,,,,,,,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,small RNAs responsible for regulating transcripts encoding ABC-type transport systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28588127,PubMed,10.1128/mBio.00473-17,MBio.2017 Jun 6;8(3). pii: e00473-17,caswellc@vt.edu,Cellular and animal models of infection demonstrated that only M2 in the AbcR sRNAs is required for Brucella virulence.,L M Sheehan 2017,2017,4 genes,Sheehan-2017-A 6-Nucleotide Regulatory Motif w,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9487,PHI:7200,,no data found,,,,,,AbcR2,,,,,,,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,small RNAs responsible for regulating transcripts encoding ABC-type transport systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28588127,PubMed,10.1128/mBio.00473-17,MBio.2017 Jun 6;8(3). pii: e00473-17,caswellc@vt.edu,Cellular and animal models of infection demonstrated that only M2 in the AbcR sRNAs is required for Brucella virulence.,L M Sheehan 2017,2017,4 genes,Sheehan-2017-A 6-Nucleotide Regulatory Motif w,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9488,PHI:7199,,no data found,,,,,,AbcR1,,,,,,PHI:7200,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,small RNAs responsible for regulating transcripts encoding ABC-type transport systems,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28588127,PubMed,10.1128/mBio.00473-17,MBio.2017 Jun 6;8(3). pii: e00473-17,caswellc@vt.edu,Cellular and animal models of infection demonstrated that only M2 in the AbcR sRNAs is required for Brucella virulence.,L M Sheehan 2017,2017,4 genes,Sheehan-2017-A 6-Nucleotide Regulatory Motif w,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9489,PHI:7200,,no data found,,,,,,AbcR2,,,,,,PHI:7199,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,small RNAs responsible for regulating transcripts encoding ABC-type transport systems,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28588127,PubMed,10.1128/mBio.00473-17,MBio.2017 Jun 6;8(3). pii: e00473-17,caswellc@vt.edu,Cellular and animal models of infection demonstrated that only M2 in the AbcR sRNAs is required for Brucella virulence.,L M Sheehan 2017,2017,4 genes,Sheehan-2017-A 6-Nucleotide Regulatory Motif w,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9490,PHI:7199,,no data found,,,,,,AbcR1,,abcR-M1,,,,,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,small RNAs responsible for regulating transcripts encoding ABC-type transport systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,28588127,PubMed,10.1128/mBio.00473-17,MBio.2017 Jun 6;8(3). pii: e00473-17,caswellc@vt.edu,Cellular and animal models of infection demonstrated that only M2 in the AbcR sRNAs is required for Brucella virulence.,L M Sheehan 2017,2017,4 genes,Sheehan-2017-A 6-Nucleotide Regulatory Motif w,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9491,PHI:7200,,no data found,,,,,,AbcR2,,abcR-M2,,,,,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,small RNAs responsible for regulating transcripts encoding ABC-type transport systems,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,28588127,PubMed,10.1128/mBio.00473-17,MBio.2017 Jun 6;8(3). pii: e00473-17,caswellc@vt.edu,Cellular and animal models of infection demonstrated that only M2 in the AbcR sRNAs is required for Brucella virulence.,L M Sheehan 2017,2017,4 genes,Sheehan-2017-A 6-Nucleotide Regulatory Motif w,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9492,PHI:7201,UniProt,Q2YKP4,GenBank,CAJ12778,,,2308,bab2_0612,chromosome II,,,,,,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,putative glutamate-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28588127,PubMed,10.1128/mBio.00473-17,MBio.2017 Jun 6;8(3). pii: e00473-17,caswellc@vt.edu,Cellular and animal models of infection demonstrated that only M2 in the AbcR sRNAs is required for Brucella virulence.,L M Sheehan 2017,2017,4 genes,Sheehan-2017-A 6-Nucleotide Regulatory Motif w,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9493,PHI:7202,UniProt,Q2YK03,GenBank,CAJ13045,,,2308,bab2_0879,chromosome II,,,,,,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,putativepolyamine-bindingprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28588127,PubMed,10.1128/mBio.00473-17,MBio.2017 Jun 6;8(3). pii: e00473-17,caswellc@vt.edu,Cellular and animal models of infection demonstrated that only M2 in the AbcR sRNAs is required for Brucella virulence.,L M Sheehan 2017,2017,4 genes,Sheehan-2017-A 6-Nucleotide Regulatory Motif w,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9494,PHI:7203,UniProt,J9VPP4,GenBank,AFR93680,,,H99,Qsp1,chromosome 3,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung,autoregulatory signaling secreted peptide,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,27212659,PubMed,10.1016/j.chom.2016.05.001,Cell Host Microbe.2016 Jun 8;19(6):849-64,hitenmadhani@gmail.com,"Qsp1 sensing requires an oligopeptide transporter, Opt1, and remarkably, cytoplasmic expression of mature Qsp1 complements multiple phenotypes of qsp1Δ.",C M Homer 2017,2017,1 gene,Homer-2016-Intracellular Action of a Secreted,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9495,PHI:7204,UniProt,P08191,GenBank,AAC77276,,,K-12,fimH,,,,,,,562,Escherichia coli,316401,H10407,urinary tract infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,intestinal epithelium,adhesin which binds mannose with stereochemical specificity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28531220,PubMed,10.1371/journal.pntd.0005586,PLoS Negl Trop Dis.2017 May 22;11(5):e0005586,jfleckenstein@wustl.edu,FimH and fimA mutants were significantly less adherent than the WT H10407 to rabbit ileal intestinal epithelium.,A Sheikh 2017,2017,2 genes,Sheikh-2017-Highly conserved type 1 pili promo,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9496,PHI:7205,UniProt,Q47223,GenBank,AF286465_1,,,LF82,fimA,,,,,,,562,Escherichia coli,316401,H10407,urinary tract infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,intestinal epithelium,"type-1 fimbrial protein, A chain",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28531220,PubMed,10.1371/journal.pntd.0005586,PLoS Negl Trop Dis.2017 May 22;11(5):e0005586,jfleckenstein@wustl.edu,FimH and fimA mutants were significantly less adherent than the WT H10407 to rabbit ileal intestinal epithelium.,A Sheikh 2017,2017,2 genes,Sheikh-2017-Highly conserved type 1 pili promo,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9497,PHI:7206,,no data found,,,,,,pms1,,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; brain,DNA mismatch repair protein,,,mismatch repair pathway,reduced virulence,,,,,,,,,,no,methyl methanesulfonate; ethidium bromide; menadione; paraquat dichloride hydrate; luperox TBH70X tert-butyl hydroperoxide solution; hydrogen peroxide; fluconazole; amphotericin B; Congo red; calcofluor white,"methyl methanesulfonate: CHEBI:25255; ethidium bromide: CHEBI:4883; menadione: CHEBI:28869; paraquat dichloride hydrate: CHEBI:28786; Luperox TBH70X tert-butyl hydroperoxide: CHEBI:64090; hydrogen peroxide: CHEBI:16240; fluconazole: CHEBI:46081, CAS:86386-73-4; amphotericin B: CHEBI:2682; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011",,,,,gene mutation; gene complementation,,,YVS,28559486,PubMed,10.1128/mBio.00595-17,MBio.2017 May 30;8(3). pii: e00595-17,alexander.idnurm@unimelb.edu.au,Deletion of MMR components leads to rapid resistance to antifungal agents.,K J Boyce 2017,2017,3 genes,Boyce-2017-Mismatch Repair of DNA Replication,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9498,PHI:7207,UniProt,Q5KN74,GenBank,AAW41279,,,JEC21,msh2,chromosome 1,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; brain,DNA mismatch repair protein,,,mismatch repair pathway,unaffected pathogenicity,,,,,,,,,,no,methyl methanesulfonate; ethidium bromide; menadione; paraquat dichloride hydrate; luperox TBH70X tert-butyl hydroperoxide solution; hydrogen peroxide; fluconazole; amphotericin B; Congo red; calcofluor white,"methyl methanesulfonate: CHEBI:25255; ethidium bromide: CHEBI:4883; menadione: CHEBI:28869; paraquat dichloride hydrate: CHEBI:28786; Luperox TBH70X tert-butyl hydroperoxide: CHEBI:64090; hydrogen peroxide: CHEBI:16240; fluconazole: CHEBI:46081, CAS:86386-73-4; amphotericin B: CHEBI:2682; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011",,,,,gene mutation; gene complementation,,,YVS,28559486,PubMed,10.1128/mBio.00595-17,MBio.2017 May 30;8(3). pii: e00595-17,alexander.idnurm@unimelb.edu.au,Deletion of MMR components leads to rapid resistance to antifungal agents.,K J Boyce 2017,2017,3 genes,Boyce-2017-Mismatch Repair of DNA Replication,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9499,PHI:7208,UniProt,J9VQQ5,GenBank,OXB36749,,,CCTP51,mlh1,,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; brain,DNA mismatch repair protein,,,mismatch repair pathway,unaffected pathogenicity,,,,,,,,,,no,methyl methanesulfonate; ethidium bromide; menadione; paraquat dichloride hydrate; luperox TBH70X tert-butyl hydroperoxide solution; hydrogen peroxide; fluconazole; amphotericin B; Congo red; calcofluor white,"methyl methanesulfonate: CHEBI:25255; ethidium bromide: CHEBI:4883; menadione: CHEBI:28869; paraquat dichloride hydrate: CHEBI:28786; Luperox TBH70X tert-butyl hydroperoxide: CHEBI:64090; hydrogen peroxide: CHEBI:16240; fluconazole: CHEBI:46081, CAS:86386-73-4; amphotericin B: CHEBI:2682; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011",,,,,gene mutation; gene complementation,,,YVS,28559486,PubMed,10.1128/mBio.00595-17,MBio.2017 May 30;8(3). pii: e00595-17,alexander.idnurm@unimelb.edu.au,Deletion of MMR components leads to rapid resistance to antifungal agents.,K J Boyce 2017,2017,3 genes,Boyce-2017-Mismatch Repair of DNA Replication,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9500,PHI:7209,UniProt,O13289,GenBank,AAC39448,,,ATCC 10261,cat1,,,,,,,5476,Candida albicans,,CEC2908,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,catalase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,28542620,PubMed,10.1371/journal.ppat.1006405,PLoS Pathog.2017 May 22;13(5):e1006405,al.brown@abdn.ac.uk,Catalase inactivation does not significantly perturb the virulence of C.albicans in models of systemic infection.,A Pradhan 2017,2017,1 gene,Pradhan-2017-Elevated catalase expression in a,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9501,PHI:7209,UniProt,O13289,GenBank,AAC39448,,,ATCC 10261,cat1,,,,,,,5476,Candida albicans,,CEC2908,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,catalase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,28542620,PubMed,10.1371/journal.ppat.1006405,PLoS Pathog.2017 May 22;13(5):e1006405,al.brown@abdn.ac.uk,Catalase inactivation does not significantly perturb the virulence of C.albicans in models of systemic infection.,A Pradhan 2017,2017,1 gene,Pradhan-2017-Elevated catalase expression in a,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9502,PHI:7210,UniProt,A0A0F6AZ24,GenBank,ACY87498,,,14028S,STM14_1001,,,,,,PHI:7211; PHI:7212; PHI:7213; PHI:7214; PHI:7215; PHI:7216; PHI:7217,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; liver; spleen,putative cytoplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28575106,PubMed,10.1371/journal.ppat.1006429,PLoS Pathog.2017 Jun 2;13(6):e1006429,wanglei@nankai.edu.cn,"SPI-14 is not involved in systemic infection, and the attenuated virulence of the SPI-14 mutant observed in orally infected mice was likely due to the defect in intestinal invasion.",L Jiang 2017,2017,8 genes,Jiang-2017-Signal transduction pathway mediate,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9503,PHI:7211,UniProt,A0A0F6AZ25,GenBank,ACY87499,,,14028S,STM14_1002,,,,,,PHI:7210; PHI:7212; PHI:7213; PHI:7214; PHI:7215; PHI:7216; PHI:7217,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; liver; spleen,putative electron transfer protein beta subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28575106,PubMed,10.1371/journal.ppat.1006429,PLoS Pathog.2017 Jun 2;13(6):e1006429,wanglei@nankai.edu.cn,"SPI-14 is not involved in systemic infection, and the attenuated virulence of the SPI-14 mutant observed in orally infected mice was likely due to the defect in intestinal invasion.",L Jiang 2017,2017,8 genes,Jiang-2017-Signal transduction pathway mediate,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9504,PHI:7212,UniProt,A0A0F6AZ26,GenBank,ACY87500,,,14028S,STM14_1003,,,,,,PHI:7210; PHI:7211; PHI:7213; PHI:7214; PHI:7215; PHI:7216; PHI:7217,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; liver; spleen,putative electron transfer protein alpha subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28575106,PubMed,10.1371/journal.ppat.1006429,PLoS Pathog.2017 Jun 2;13(6):e1006429,wanglei@nankai.edu.cn,"SPI-14 is not involved in systemic infection, and the attenuated virulence of the SPI-14 mutant observed in orally infected mice was likely due to the defect in intestinal invasion.",L Jiang 2017,2017,8 genes,Jiang-2017-Signal transduction pathway mediate,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9505,PHI:7213,,no data found,,,,,,STM14_1004,,,,,,PHI:7210; PHI:7211; PHI:7212; PHI:7214; PHI:7215; PHI:7216; PHI:7217,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; liver; spleen,pseudogene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28575106,PubMed,10.1371/journal.ppat.1006429,PLoS Pathog.2017 Jun 2;13(6):e1006429,wanglei@nankai.edu.cn,"SPI-14 is not involved in systemic infection, and the attenuated virulence of the SPI-14 mutant observed in orally infected mice was likely due to the defect in intestinal invasion.",L Jiang 2017,2017,8 genes,Jiang-2017-Signal transduction pathway mediate,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9506,PHI:7214,UniProt,A0A0F6AZ27,GenBank,ACY87501,,,14028S,STM14_1005,,,,,,PHI:7210; PHI:7211; PHI:7212; PHI:7213; PHI:7215; PHI:7216; PHI:7217,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; liver; spleen,putative acyl-CoA dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28575106,PubMed,10.1371/journal.ppat.1006429,PLoS Pathog.2017 Jun 2;13(6):e1006429,wanglei@nankai.edu.cn,"SPI-14 is not involved in systemic infection, and the attenuated virulence of the SPI-14 mutant observed in orally infected mice was likely due to the defect in intestinal invasion.",L Jiang 2017,2017,8 genes,Jiang-2017-Signal transduction pathway mediate,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9507,PHI:7215,UniProt,A0A0F6AZ28,GenBank,ACY87502,,,14028S,STM14_1006,,,,,,PHI:7210; PHI:7211; PHI:7212; PHI:7213; PHI:7214; PHI:7216; PHI:7217,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; liver; spleen,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28575106,PubMed,10.1371/journal.ppat.1006429,PLoS Pathog.2017 Jun 2;13(6):e1006429,wanglei@nankai.edu.cn,"SPI-14 is not involved in systemic infection, and the attenuated virulence of the SPI-14 mutant observed in orally infected mice was likely due to the defect in intestinal invasion.",L Jiang 2017,2017,8 genes,Jiang-2017-Signal transduction pathway mediate,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9508,PHI:7216,UniProt,A0A0F6AZ29,GenBank,ACY87503,,,14028S,STM14_1007,,,,,,PHI:7210; PHI:7211; PHI:7212; PHI:7213; PHI:7214; PHI:7215; PHI:7217,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; liver; spleen,putative dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28575106,PubMed,10.1371/journal.ppat.1006429,PLoS Pathog.2017 Jun 2;13(6):e1006429,wanglei@nankai.edu.cn,"SPI-14 is not involved in systemic infection, and the attenuated virulence of the SPI-14 mutant observed in orally infected mice was likely due to the defect in intestinal invasion.",L Jiang 2017,2017,8 genes,Jiang-2017-Signal transduction pathway mediate,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9509,PHI:7217,UniProt,A0A0F6AZ30,GenBank,ACY87504,,,14028S,STM14_1008,,,,,,PHI:7210; PHI:7211; PHI:7212; PHI:7213; PHI:7214; PHI:7215; PHI:7216,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; liver; spleen,"low oxygen induced factor A, putative transcriptional regulator",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28575106,PubMed,10.1371/journal.ppat.1006429,PLoS Pathog.2017 Jun 2;13(6):e1006429,wanglei@nankai.edu.cn,"SPI-14 is not involved in systemic infection, and the attenuated virulence of the SPI-14 mutant observed in orally infected mice was likely due to the defect in intestinal invasion.",L Jiang 2017,2017,8 genes,Jiang-2017-Signal transduction pathway mediate,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9510,PHI:7217,UniProt,A0A0F6AZ30,GenBank,ACY87504,,,14028S,STM14_1008,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; liver; spleen,"low oxygen induced factor A, putative transcriptional regulator",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28575106,PubMed,10.1371/journal.ppat.1006429,PLoS Pathog.2017 Jun 2;13(6):e1006429,wanglei@nankai.edu.cn,"SPI-14 is not involved in systemic infection, and the attenuated virulence of the SPI-14 mutant observed in orally infected mice was likely due to the defect in intestinal invasion.",L Jiang 2017,2017,8 genes,Jiang-2017-Signal transduction pathway mediate,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9511,PHI:7218,UniProt,P9WF41,GenBank,CCP46238,,,H37Rv,whiB3,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,redox-and pH-responsive transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28542477,PubMed,10.1371/journal.ppat.1006389,PLoS Pathog.2017 May 22;13(5):e1006389,asteyn@uab.edu,Infection with the Mtb whiB3 mutant or polyketide mutants had little effect on the macrophage cell cycle and emulated the uninfected cells.,B M Cumming 2017,2017,4 genes,Cumming-2017-Mycobacterium tuberculosis arrest,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9512,PHI:7219,UniProt,A0A0T9DH93,GenBank,CKS33897,,,Bir 180,mas,,Tn:mas,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,multifunctional mycocerosic acid synthase membrane-associated MAS,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28542477,PubMed,10.1371/journal.ppat.1006389,PLoS Pathog.2017 May 22;13(5):e1006389,asteyn@uab.edu,Infection with the Mtb whiB3 mutant or polyketide mutants had little effect on the macrophage cell cycle and emulated the uninfected cells.,B M Cumming 2017,2017,4 genes,Cumming-2017-Mycobacterium tuberculosis arrest,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9513,PHI:7220,UniProt,P9WQE7,GenBank,CCP45734,,,H37Rv,ppsA,,Tn:ppsA,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,phthiocerol synthesis polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28542477,PubMed,10.1371/journal.ppat.1006389,PLoS Pathog.2017 May 22;13(5):e1006389,asteyn@uab.edu,Infection with the Mtb whiB3 mutant or polyketide mutants had little effect on the macrophage cell cycle and emulated the uninfected cells.,B M Cumming 2017,2017,4 genes,Cumming-2017-Mycobacterium tuberculosis arrest,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9514,PHI:7221,UniProt,P9WQE9,GenBank,CCP46654,,,H37Rv,pks2,,Tn:pks2,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28542477,PubMed,10.1371/journal.ppat.1006389,PLoS Pathog.2017 May 22;13(5):e1006389,asteyn@uab.edu,Infection with the Mtb whiB3 mutant or polyketide mutants had little effect on the macrophage cell cycle and emulated the uninfected cells.,B M Cumming 2017,2017,4 genes,Cumming-2017-Mycobacterium tuberculosis arrest,BATCH_070B,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9515,PHI:7222,UniProt,Q4WWU2,GenBank,EAL92861,,,Af293,mybA,chromosome 3,,,,,,746128,Aspergillus fumigatus,1266464,akuBKU80,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,lung,transcription factor,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28677124,PubMed,10.1111/mmi.13744,Mol Microbiol.2017 Jul 5,ozgur.bayram@nuim.ie,MybA protein controls the expression of enzymes involved in trehalose biosynthesis as well as other cell wall and membrane associated proteins and ROS scavenging enzymes.,I Valsecchi 2017,2017,1 gene,"Valsecchi-2017-MybA, a transcription factor in",BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9516,PHI:7223,UniProt,P0CT09,GenBank,EHA52255,,,70-15,Moend3,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,actin cytoskeleton-regulatory complex protein,,,,reduced virulence,yes,yes,yes,,,wild type,reduced,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28628655,PubMed,10.1371/journal.ppat.1006449,PLoS Pathog.2017 Jun 19;13(6):e1006449,zhgzhang@njau.edu.cn,MoEnd3 is dispensable for vegetative growth and conidiation but not sexual reproduction.,X Li 2017,2017,1 gene,Li-2017-MoEnd3 regulates appressorium formatio,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9517,PHI:7223,UniProt,P0CT09,GenBank,EHA52255,,,70-15,Moend3,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,actin cytoskeleton-regulatory complex protein,,,,reduced virulence,yes,yes,yes,,,wild type,reduced,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28628655,PubMed,10.1371/journal.ppat.1006449,PLoS Pathog.2017 Jun 19;13(6):e1006449,zhgzhang@njau.edu.cn,MoEnd3 is dispensable for vegetative growth and conidiation but not sexual reproduction.,X Li 2017,2017,1 gene,Li-2017-MoEnd3 regulates appressorium formatio,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9518,PHI:7224,UniProt,P0CL52,GenBank,AAL21762,,,LT2; SGSC 1412; ATCC 700720,SipA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28630067,PubMed,10.1128/IAI.00393-17,Infect Immun.2017 Jun 19. pii: IAI.00393-17,donal.wall@glasgow.ac.uk,"In macrophages, SipA induced increased caspase-3 activation early in infection, whereas, in polymorphonuclear leukocytes SipA, or other Salmonella Pathogenicity Island 1 effectors had no effect on induction of caspase-3 activation either alone or in the presence of whole bacteria.",A McIntosh 2017,2017,1 gene,McIntosh-2017-SipA activation of caspase-3 is,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9519,PHI:7224,UniProt,P0CL52,GenBank,AAL21762,,,LT2; SGSC 1412; ATCC 700720,SipA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),polymorphonuclear leukocytes,,,blood,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28630067,PubMed,10.1128/IAI.00393-17,Infect Immun.2017 Jun 19. pii: IAI.00393-17,donal.wall@glasgow.ac.uk,"In macrophages SipA induced increased caspase-3 activation early in infection, whereas, in polymorphonuclear leukocytes SipA, or other Salmonella Pathogenicity Island 1 effectors, had no effect on induction of caspase-3 activation either alone or in the presence of whole bacteria.",A McIntosh 2017,2017,1 gene,McIntosh-2017-SipA activation of caspase-3 is,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9520,PHI:7225,UniProt,A0A0F6B1M0,GenBank,ACY88406,,,14028S,ydcR,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; cecum,putative transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28674150,PubMed,10.1074/mcp.M117.068296,Mol Cell Proteomics.2017 Jul 3. pii: mcp.M117.068296,xiaoyun.liu@pku.edu.cn,"Genetic ablation of ydcR did not compromise Salmonella growth in vitro, bacterial invasion or intracellular multiplication during infection of host epithelial cells.",Y Liu 2017,2017,1 gene,Liu-2017-Temporal regulation of a Salmonella T,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9521,PHI:7226,UniProt,Q875L7,GenBank,AAN46744,,,Guy11,tps1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,trehalose-6-phosphate synthase,,,trehalose metabolism,reduced virulence,,no,yes,yes,,reduced,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,12514128,PubMed,10.1093/emboj/cdg018,EMBO J.2003 Jan 15;22(2):225-35.,N.J.Talbot@exeter.ac.uk,"Trehalose synthesis, but not its subsequent breakdown, was required for primary plant infection by M.grisea, while trehalose degradation was important for efficient development of the fungus in plant tissue following initial infection.",A J Foster 2003,2003,3 genes,Foster-2003-Trehalose synthesis and metabolism,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9522,PHI:7227,UniProt,O42622,GenBank,AAB88889,,,4091-5-8,nth1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,neutral trehalase,,,trehalose metabolism,reduced virulence,,no,no,yes,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,12514128,PubMed,10.1093/emboj/cdg018,EMBO J.2003 Jan 15;22(2):225-35.,N.J.Talbot@exeter.ac.uk,"Trehalose synthesis, but not its subsequent breakdown, was required for primary plant infection by M.grisea, while trehalose degradation was important for efficient development of the fungus in plant tissue following initial infection.",A J Foster 2003,2003,3 genes,Foster-2003-Trehalose synthesis and metabolism,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9523,PHI:7228,UniProt,Q8J0H8,GenBank,AAN38003,,,Guy11,tre1,,tre1::Hph,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cell wall-localized enzyme with characteristics of both neutral and acidic trehalases,,,trehalose metabolism,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,12514128,PubMed,10.1093/emboj/cdg018,EMBO J.2003 Jan 15;22(2):225-35.,N.J.Talbot@exeter.ac.uk,"Trehalose synthesis, but not its subsequent breakdown, was required for primary plant infection by M.grisea, while trehalose degradation was important for efficient development of the fungus in plant tissue following initial infection.",A J Foster 2003,2003,3 genes,Foster-2003-Trehalose synthesis and metabolism,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9524,PHI:7229,UniProt,J9VKV9,GenBank,AFR94071,,,H99,Gsb1,chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),A/JJmsSlc,,,,"general stress-related basic, leucine-zipper (bZip) protein",,,,reduced virulence,yes,,,,,,,reduced,,no,Congo red; SDS; caffeine; diamide; H2O2; KCl; NaCl; CdSO4; menadione; tert-butyl-hydrogen peroxide; NaNO2; hydroxyurea; tunicamycin; DTT,Congo red: CHEBI:34653; SDS: CHEBI:8984; caffeine: CHEBI:27732; H2O2: CHEBI:16240; KCl: CHEBI:32588; NaCl: CHEBI:26710; CdSO4: CHEBI:50292; menadione: CHEBI:28869; tert-butyl-hydrogen peroxide: CHEBI:64090; NaNO2: CHEBI:78870; hydroxyurea: CHEBI:44423; tunicamycin: CHEBI:29699; DTT: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,28642475,PubMed,10.1038/s41598-017-04290-8,Sci Rep.2017 Jun 22;7(1):4044,hyunkang@cau.ac.kr,Gsb1Δ showed defective mating and abnormal cell-cycle progression.,S A Cheon 2017,,1 gene,"Cheon-2017-A novel bZIP protein, Gsb1, is requ",BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9525,PHI:7230,UniProt,Q9C402,GenBank,AF324862_1,,,H99,SOD1,,,,,,,5207,Cryptococcus neoformans,235443,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,superoxide dismutase,,,,reduced virulence,,,,,,,,wild type,,no,tert-butylhydroperoxide; paraquat; oxytetracycline,tert-butylhydroperoxide: CHEBI:64090; paraquat: CHEBI:34905; oxytetracycline: CHEBI:27701,,,,,gene disruption; gene complementation,,,YVS,12496163,PubMed,10.1128/IAI.71.1.173-180.2003,Infect Immun.2003 Jan;71(1):173-80,gary.cox@duke.edu,The sod1 mutant strains had marked decreases in SOD activity and were strikingly more susceptible to reactive oxygen species in vitro.,G M Cox 2003,2003,1 gene,Cox-2003-Superoxide dismutase influences the v,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9526,PHI:7231,UniProt,Q9P8P2,GenBank,AF223383_1,,,H99,plb1,,,,,,,5207,Cryptococcus neoformans,235443,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; lymph node; brain; spleen,secreted phospholipase B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,15039347,PubMed,10.1128/IAI.72.4.2229-2239.2004,Infect Immun.2004 Apr;72(4):2229-39,lesleyw@icpmr.wsahs.nsw.gov.au,"PLB activity was necessary for the initiation of interstitial pulmonary infections and for dissemination from the lung via the lymphatics and blood. PLB was not, however, essential for the establishment of neurological infections when cryptococci were presented within, or after passage through, mononuclear phagocytes.",R Santangelo 2004,2004,1 gene,Santangelo-2004-Role of extracellular phosphol,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9527,PHI:7232,UniProt,P23316,GenBank,BAA07738,,,IFO1060,chs1,,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,chitin synthase involved in the repair of damaged chitin,,,,lethal,,,,,,,,,,yes,,,,,,,gene mutation,,,YVS,8636047,PubMed,10.1128/jb.178.8.2416-2419.1996,J Bacteriol.1996 Apr;178(8):2416-9,hisafumi.okabe@roche.com,There were only small differences in virulence to immunocompromised mice of homozygous chs2D and homozygous chs3D null mutants.,T Mio 1996,1996,3 genes,Mio-1996-Role of three chitin synthase genes i,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9528,PHI:7233,UniProt,P30572,GenBank,AAB59308,,,B-792,chs2,,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,chitin synthase required for primary septum formation,,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white; sorbitol,calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene mutation,,,YVS,8636047,PubMed,10.1128/jb.178.8.2416-2419.1996,J Bacteriol.1996 Apr;178(8):2416-9,hisafumi.okabe@roche.com,There were only small differences in virulence to immunocompromised mice of homozygous chs2D and homozygous chs3D null mutants.,T Mio 1996,1996,3 genes,Mio-1996-Role of three chitin synthase genes i,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9529,PHI:7234,UniProt,P30573,GenBank,BAA02707,,,IFO1060,chs3,,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,chitin synthase responsible for overall chitin synthesis,,,,unaffected pathogenicity,,,,,,,,reduced,,no,calcofluor white; sorbitol,calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene mutation,,,YVS,8636047,PubMed,10.1128/jb.178.8.2416-2419.1996,J Bacteriol.1996 Apr;178(8):2416-9,hisafumi.okabe@roche.com,There were only small differences in virulence to immunocompromised mice of homozygous chs2D and homozygous chs3D null mutants.,T Mio 1996,1996,3 genes,Mio-1996-Role of three chitin synthase genes i,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9530,PHI:7235,,no data found,GenBank,KX755251,,,W16,cgABCF2,,,,,,,474922,Colletotrichum gloeosporioides,,W16,fruit rot,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit; leaf,ATP-binding cassette (ABC) protein,,,,reduced virulence,,yes,,,,reduced,reduced,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28645773,PubMed,10.1016/j.micpath.2017.06.028,Microb Pathog.2017 Jun 20;110:85-92,zhangjunxiang@caas.cn,"The CgABCF2 gene was found to be necessary for appressorial formation, pathogenicity as well as sexual reproduction but not for conidial germination.",Z Zhou 2017,2017,1 gene,Zhou-2017-ABC protein CgABCF2 is required for,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9531,PHI:7236,UniProt,O30916,GenBank,AAC46234,,,ATCC 14028s,SopB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HEK-293 cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28664153,PubMed,10.3389/fcimb.2017.00257,FrontCellInfect Microbiol.2017 Jun 15;7:257,r.teasdale@uq.edu.au,"Host gene alteration data available for SNX18. Quantification of bacteria uptake revealed that overexpression of SNX18 increased bacteria internalization, whereas a decrease was detected in cells overexpressing the phosphoinositide-binding mutant R303Q, the ΔSH3 mutant, and in cells where endogenous levels of SNX18 were knocked-down.",D Liebl 2017,2017,1 gene,Liebl-2017-SopB-Mediated Recruitment of SNX18,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9532,PHI:7237,UniProt,Q79LY0,GenBank,AF469470_3,,,DC3000,HopPtoD2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia,,,leaf,type III effector,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,12828637,PubMed,10.1046/j.1365-2958.2003.03616.x,Mol Microbiol.2003 Jul;49(2):389-400,sh53@umail.umd.edu,A ΔhopPtoD2 mutant of DC3000 exhibited strongly reduced virulence in Arabidopsis thaliana.,J R Bretz 2003,2003,1 gene,Bretz-2003-A translocated protein tyrosine pho,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9533,PHI:7238,,no data found,,,,,,elrA,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; urinary bladder,enterococcal leucine-rich protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28676674,PubMed,10.1038/s41598-017-04875-3,Sci Rep. 2017 Jul 4;7(1):4581,alexandre.jamet@inra.fr,"The specific interaction between the E. faecalis ElrA and the human FHL2, a member of the Four-and-a-Half LIM Domains Protein family was required for virulence.",A Jamet 2017,2017,1 gene,Jamet-2017-The Enterococcus faecalis virulence,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9534,PHI:7238,,no data found,,,,,,elrA,,elrAΔFID,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; urinary bladder,enterococcal leucine-rich protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,28676674,PubMed,10.1038/s41598-017-04875-3,Sci Rep. 2017 Jul 4;7(1):4581,alexandre.jamet@inra.fr,"The specific interaction between the E. faecalis ElrA and the human FHL2, a member of the Four-and-a-Half LIM Domains Protein family was required for virulence.",A Jamet 2017,2017,1 gene,Jamet-2017-The Enterococcus faecalis virulence,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9535,PHI:7239,,no data found,,,,,,agI/II,,,,,,,1307,Streptococcus suis,568813,ST7 serotype 2 strain SC84,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,nasal cavity; mouth; saliva; tonsil,multimodal adhesion protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28705175,PubMed,10.1186/s13567-017-0443-4,Vet Res. 2017 Jul 14;48(1):39,marcelo.gottschalk@umontreal.ca,"The data demonstrated that the serotype 9 AgI/II participated in self-aggregation, salivary glycoprotein 340-related aggregation, biofilm formation and increased strain resistance to low pH, as well as in bacterial adhesion to extracellular matrix proteins and epithelial cells.",S Chuzevill 2017,2017,1 gene,Chuzeville-2017-Serotype-specific role of anti,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9536,PHI:7239,,no data found,,,,,,agI/II,,,,,,,1307,Streptococcus suis,,serotype 9 strain 1135776,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,nasal cavity; mouth; saliva; tonsil,multimodal adhesion protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28705175,PubMed,10.1186/s13567-017-0443-4,Vet Res. 2017 Jul 14;48(1):39,marcelo.gottschalk@umontreal.ca,"The data demonstrated that the serotype 9 AgI/II participated in self-aggregation, salivary glycoprotein 340-related aggregation, biofilm formation and increased strain resistance to low pH, as well as in bacterial adhesion to extracellular matrix proteins and epithelial cells.",S Chuzevill 2017,2017,1 gene,Chuzeville-2017-Serotype-specific role of anti,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9537,PHI:7240,UniProt,Q9HGU2,GenBank,AF286533_1,,,,fmk1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,root; fruit,MAP kinase,,,MAPK pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,14977985,PubMed,10.1128/IAI.72.3.1760-1766.2004,Infect Immun. 2004 Mar;72(3):1760-6,ge2dipia@uco.es,The results obtained with the F. oxysporum knockout mutants suggested that certain virulence factors essential in plant pathogenesis were dispensable in animal pathogenesis and vice versa.,M Ortoneda 2004,2004,3 genes,Ortoneda-2004-Fusarium oxysporum as a multihos,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9538,PHI:7240,UniProt,Q9HGU2,GenBank,AF286533_1,,,,fmk1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,rodents,10090,Mus musculus (related: house mouse),OF1,,,liver; spleen; kidney; lung; brain,MAP kinase,,,MAPK pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,14977985,PubMed,10.1128/IAI.72.3.1760-1766.2004,Infect Immun. 2004 Mar;72(3):1760-6,ge2dipia@uco.es,The results obtained with the F. oxysporum knockout mutants suggested that certain virulence factors essential in plant pathogenesis were dispensable in animal pathogenesis and vice versa.,M Ortoneda 2004,2004,3 genes,Ortoneda-2004-Fusarium oxysporum as a multihos,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9539,PHI:7241,UniProt,Q870A3,GenBank,AAM95700,,,,pacC,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,root; fruit,zinc finger transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,14977985,PubMed,10.1128/IAI.72.3.1760-1766.2004,Infect Immun. 2004 Mar;72(3):1760-6,ge2dipia@uco.es,The results obtained with the F. oxysporum knockout mutants suggested that certain virulence factors essential in plant pathogenesis were dispensable in animal pathogenesis and vice versa.,M Ortoneda 2004,2004,3 genes,Ortoneda-2004-Fusarium oxysporum as a multihos,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9540,PHI:7241,UniProt,Q870A3,GenBank,AAM95700,,,,pacC,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,rodents,10090,Mus musculus (related: house mouse),OF1,,,liver; spleen; kidney; lung; brain,zinc finger transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,14977985,PubMed,10.1128/IAI.72.3.1760-1766.2004,Infect Immun. 2004 Mar;72(3):1760-6,ge2dipia@uco.es,The results obtained with the F. oxysporum knockout mutants suggested that certain virulence factors essential in plant pathogenesis were dispensable in animal pathogenesis and vice versa.,M Ortoneda 2004,2004,3 genes,Ortoneda-2004-Fusarium oxysporum as a multihos,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9541,PHI:7242,UniProt,Q873Z8,GenBank,AF484941_1,,,,chsV,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,root; fruit,class V chitin synthase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,14977985,PubMed,10.1128/IAI.72.3.1760-1766.2004,Infect Immun. 2004 Mar;72(3):1760-6,ge2dipia@uco.es,The results obtained with the F. oxysporum knockout mutants suggested that certain virulence factors essential in plant pathogenesis were dispensable in animal pathogenesis and vice versa.,M Ortoneda 2004,2004,3 genes,Ortoneda-2004-Fusarium oxysporum as a multihos,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9542,PHI:7242,UniProt,Q873Z8,GenBank,AF484941_1,,,,chsV,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,vascular wilt,rodents,10090,Mus musculus (related: house mouse),OF1,,,lung,class V chitin synthase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,14977985,PubMed,10.1128/IAI.72.3.1760-1766.2004,Infect Immun. 2004 Mar;72(3):1760-6,ge2dipia@uco.es,The results obtained with the F. oxysporum knockout mutants suggested that certain virulence factors essential in plant pathogenesis were dispensable in animal pathogenesis and vice versa.,M Ortoneda 2004,2004,3 genes,Ortoneda-2004-Fusarium oxysporum as a multihos,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9543,PHI:7243,UniProt,A0A1W5T7B8,GenBank,ARF07871,,,BCC 2660,pks15,,,,,,,176275,Beauveria bassiana,655819,BCC 2660,white muscardine,moths,7107,Spodoptera exigua (related: beet armyworm),,,,larva,clade III polyketide synthase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene disruption,,,YVS,28705395,PubMed,10.1016/j.funbio.2017.04.007,Fungal Biol. 2017 Aug;121(8):664-675,alongkorn@biotec.or.th,"The mortality rate of amoebae engulfing Δpks15 was decreased, Δpks15 mutant had a reduced ability to cope with phagocytosis.",W Toopaang 2017,2017,1 gene,Toopaang-2017-Targeted disruption of the polyk,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9544,PHI:7243,UniProt,A0A1W5T7B8,GenBank,ARF07871,,,BCC 2660,pks15,,,,,,,176275,Beauveria bassiana,655819,BCC 2660,white muscardine,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,clade III polyketide synthase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene disruption,,,YVS,28705395,PubMed,10.1016/j.funbio.2017.04.007,Fungal Biol. 2017 Aug;121(8):664-675,alongkorn@biotec.or.th,"The mortality rate of amoebae engulfing Δpks15 was decreased, Δpks15 mutant had a reduced ability to cope with phagocytosis.",W Toopaang 2017,2017,1 gene,Toopaang-2017-Targeted disruption of the polyk,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9545,PHI:7244,,no data found,GenBank,ZP_03830919,,,WPP14,GCS,,,,,,,554,Pectobacterium carotovorum,558270,subsp. carotovorum strain WPP14,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Yukon Gold,,,tuber,globin coupled sensor protein,,,signaling and quorum sensing pathway,reduced virulence,,,,,,,,,,no,H2O2; salicylic acid; cinnamic acid; N-(3-oxo)-hexanoyl L-homoserine lactone; N-3-(4-bromophenyl)-propanoyl L-homoserine lactone,H2O2: CHEBI:16240; salicylic acid: CHEBI:16914; cinnamic acid: CHEBI:27386; N-(3-oxo)-hexanoyl L-homoserine lactone: CHEBI:6378; N-3-(4-bromophenyl)-propanoyl L-homoserine lactone: CAS:1644190-32-8,,,,,gene deletion,,,YVS,28612602,PubMed,10.1021/acschembio.7b00380,ACS Chem Biol. 2017 Jun 28,emily.weinert@emory.edu,"PccGCS deletion strain was more sensitive to plant-derived phenolic acids, which can function as quorum sensing inhibitors, and exhibited increased N-acylhomoserine lactone (AHL) production.",J L Burns 2017,2017,1 gene,Burns-2017-Oxygen-Dependent Globin Coupled Sen,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9546,PHI:7245,,no data found,FVG,g8266,,,,FvSTR1,Scaffold11:901086..903663 (- strand),deltastr14,,,,,232082,Fusarium virguliforme,994087,Mont-1,sudden death syndrome,eudicots,3847,Glycine max (related: soybean),cv. Spencer,,,root,striatin orthologue required for asexual development and virulence,,,MAP kinase signalling pathway,loss of pathogenicity,,,,,,reduced; aberrant,,wild type,,no,,,,,,,gene disruption,,,YVS,28643182,PubMed,10.1007/s00253-017-8387-1,Appl Microbiol Biotechnol. 2017 Jun 22,amfakhou@siu.edu,"FvSTR1 had a role in the secretion of factors that are important in virulence, such as toxins, cell wall-degrading enzymes or other fungal metabolites that are involved in pathogenesis.",K T Islam 2017,2017,3 genes,"Islam-2017-FvSTR1, a striatin orthologue in Fu",BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9547,PHI:7245,,no data found,FVG,g8266,,,,FvSTR1,Scaffold11:901086..903663 (- strand),deltastr32,,,,,232082,Fusarium virguliforme,994087,Mont-1,sudden death syndrome,eudicots,3847,Glycine max (related: soybean),cv. Spencer,,,root,striatin orthologue required for asexual development and virulence,,,MAP kinase signalling pathway,loss of pathogenicity,,,,,,reduced; aberrant,,wild type,,no,,,,,,,gene disruption,,,YVS,28643182,PubMed,10.1007/s00253-017-8387-1,Appl Microbiol Biotechnol. 2017 Jun 22,amfakhou@siu.edu,"FvSTR1 had a role in the secretion of factors that are important in virulence, such as toxins, cell wall-degrading enzymes or other fungal metabolites that are involved in pathogenesis.",K T Islam 2017,2017,3 genes,"Islam-2017-FvSTR1, a striatin orthologue in Fu",BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9548,PHI:7245,,no data found,FVG,g8266,,,,FvSTR1,Scaffold11:901086..903663 (- strand),Ectstr4 (ectopic),,,,,232082,Fusarium virguliforme,994087,Mont-1,sudden death syndrome,eudicots,3847,Glycine max (related: soybean),cv. Spencer,,,root,striatin orthologue required for asexual development and virulence,,,MAP kinase signalling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,28643182,PubMed,10.1007/s00253-017-8387-1,Appl Microbiol Biotechnol. 2017 Jun 22,amfakhou@siu.edu,"FvSTR1 had a role in the secretion of factors that are important in virulence, such as toxins, cell wall-degrading enzymes or other fungal metabolites that are involved in pathogenesis.",K T Islam 2017,2017,3 genes,"Islam-2017-FvSTR1, a striatin orthologue in Fu",BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9549,PHI:7248,UniProt,P0A9E5,GenBank,AAA87981,,,K-12,fnr,,,,,,,562,Escherichia coli,405955,APEC O1,colibacillosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,macrophage,"transcription factor, is a global regulator of pathways meant to facilitate gene expression",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28690981,PubMed,10.3389/fcimb.2017.00265,Front Cell Infect Microbiol. 2017 Jun 23;7:265,lisa.nolan@uga.edu,"FNR was found to be important to APECO1's growth in iron-deficient media and survival during oxidative stress with the mutant showing a 4-fold decrease in tolerance to oxidative stress, as compared to the wild type.",N L Barbieri 2017,2017,1 gene,Barbieri-2017-FNR Regulates the Expression of,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9550,PHI:7248,UniProt,P0A9E5,GenBank,AAA87981,,,K-12,fnr,,,,,,,562,Escherichia coli,405955,APEC O1,colibacillosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,epithelial cell,"transcription factor, is a global regulator of pathways meant to facilitate gene expression",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28690981,PubMed,10.3389/fcimb.2017.00265,Front Cell Infect Microbiol. 2017 Jun 23;7:265,lisa.nolan@uga.edu,"FNR was found to be important to APECO1's growth in iron-deficient media and survival during oxidative stress with the mutant showing a 4-fold decrease in tolerance to oxidative stress, as compared to the wild type.",N L Barbieri 2017,2017,1 gene,Barbieri-2017-FNR Regulates the Expression of,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9551,PHI:7249,UniProt,A0A0H3MZ24,GenBank,CAZ55634,,,BM407,mntE,,,,,,,1307,Streptococcus suis,,serotype 2 strain SC19,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; heart; liver; spleen; lung; kidney,manganese export protein,,,,reduced virulence,,,,,,,,wild type,,no,MnCl2; FeSO4; Fe(NO3)3; NiSO4; ZnSO4; H2O2; diamide,"MnCl2: CHEBI:63041; FeSO4: CHEBI:75832, 3; Fe(NO3): CAS:10421-48-4; NiSO4: CHEBI:53001; ZnSO4: CHEBI:35176; H2O2: CHEBI:16240; diamide: CHEBI:48958",,,,,gene deletion: full; gene complementation,,,YVS,28629722,PubMed,10.1016/j.micpath.2017.06.022,Microb Pathog. 2017 Jun 16;110:23-30,beiwc@mail.hzau.edu.cn,Manganese homeostasis controlled by the manganese efflux system MntE was important for the pathogenesis of S. suis 2.,J Xu 2017,2017,1 gene,Xu-2017-The manganese efflux system MntE contr,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9552,PHI:7250,UniProt,A0A088U1Z5,GenBank,CDN60672,,,H111,ntrC,chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,σ54 activator protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28662146,PubMed,10.1371/journal.pone.0180362,PLoS One. 2017 Jun 29;12(6):e0180362.,leberl@botinst.uzh.ch,NtrC regulated the EPS production but had only a slight effect on biofilm formation.,Y Liu 2017,2017,1 gene,Liu-2017-NtrC-dependent control of exopolysacc,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9553,PHI:7251,UniProt,E9ETZ6,GenBank,EFZ00899,,,ARSEF 23,Mrtdc,,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seed; root,responsible for conversion of Trp to TAM,,,auxin biosynthetic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,YVS,28708056,PubMed,10.1099/mic.0.000494,Microbiology. 2017 Jul;163(7):980-991,liaoxgang@126.com,"Auxins played an important role in the ability of M. robertsii to promote plant growth, and the endogenous pathways for IAA production may also be involved in regulating entomopathogenicity.",X Liao 2017,2017,1 gene,Liao-2017-Metarhizium robertsii produces indol,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9554,PHI:7251,UniProt,E9ETZ6,GenBank,EFZ00899,,,ARSEF 23,Mrtdc,,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,responsible for conversion of Trp to TAM,,,auxin biosynthetic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,YVS,28708056,PubMed,10.1099/mic.0.000494,Microbiology. 2017 Jul;163(7):980-991,liaoxgang@126.com,"Auxins played an important role in the ability of M. robertsii to promote plant growth, and the endogenous pathways for IAA production may also be involved in regulating entomopathogenicity.",X Liao 2017,2017,1 gene,Liao-2017-Metarhizium robertsii produces indol,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9555,PHI:7252,UniProt,A0A1P8YR90,GenBank,AQA26589,,,Cand-Elsaadany; TDKH-014,INT1,,,,,,,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,kidney; liver,involved in adhesion to epithelial cells and morphologic switching to filamentous forms,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,10444345,PubMed,10.1006/mgme.1999.2875,Mol Genet Metab. 1999 Aug;67(4):343-51,bende001@tc.umn.edu,"Compared to the wild-type strain, mutant strains were associated with reduced mortality but increased C. albicans persistence in the kidney.",C M Bendel 1999,1999,1 gene,Bendel-1999-Systemic infection following intra,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9556,PHI:7253,UniProt,D4I2L5,GenBank,CBA20721,,,CFPB1430,KatA,,,,,,,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Devoe,,,fruit,monofunctional catalase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene mutation; gene complementation,,,YVS,28675630,PubMed,10.1111/mpp.12577,Mol Plant Pathol. 2017 Jul 4,elena.biosca@uv.es,"Catalases KatA and KatG are virulence factors in E. amylovora, with KatG playing a major role during host-pathogen interactions.",R D Santander 2017,2017,2 genes,Santander-2017-Erwinia amylovora catalases Kat,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9557,PHI:7254,UniProt,D4HW09,GenBank,CBA21169,,,CFPB1430,KatG,,,,,,,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Devoe,,,fruit,bifunctional catalase/peroxidase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene mutation; gene complementation,,,YVS,28675630,PubMed,10.1111/mpp.12577,Mol Plant Pathol. 2017 Jul 4,elena.biosca@uv.es,"Catalases KatA and KatG are virulence factors in E. amylovora, with KatG playing a major role during host-pathogen interactions.",R D Santander 2017,2017,2 genes,Santander-2017-Erwinia amylovora catalases Kat,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9558,PHI:7253,UniProt,D4I2L5,GenBank,CBA20721,,,CFPB1430,KatA,,,,,,PHI:7254,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Devoe,,,fruit,monofunctional catalase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene mutation,,,YVS,28675630,PubMed,10.1111/mpp.12577,Mol Plant Pathol. 2017 Jul 4,elena.biosca@uv.es,"Catalases KatA and KatG are virulence factors in E. amylovora, with KatG playing a major role during host-pathogen interactions.",R D Santander 2017,2017,2 genes,Santander-2017-Erwinia amylovora catalases Kat,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9559,PHI:7254,UniProt,D4HW09,GenBank,CBA21169,,,CFPB1430,KatG,,,,,,PHI:7253,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Devoe,,,fruit,bifunctional catalase/peroxidase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene mutation,,,YVS,28675630,PubMed,10.1111/mpp.12577,Mol Plant Pathol. 2017 Jul 4,elena.biosca@uv.es,"Catalases KatA and KatG are virulence factors in E. amylovora, with KatG playing a major role during host-pathogen interactions.",R D Santander 2017,2017,2 genes,Santander-2017-Erwinia amylovora catalases Kat,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9560,PHI:7255,UniProt,A0A0H2X3T0,GenBank,AAY47612,,,8004,XC_0531,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,putative C-type cytochrome biogenesis protein,,,,reduced virulence,,,,,,,,reduced,,no,dithiothreitol; CuSO4,dithiothreitol: CHEBI:42170; CuSO4: CHEBI:23414,,,,,gene deletion: full; gene complementation,,,YVS,28655353,PubMed,10.1186/s12866-017-1056-9,BMC Microbiol. 2017 Jun 27;17(1):142,lugt@gxu.edu.cn,"Mutant of XC_0531 was deficient in biosynthesis of c-type cytochromes, XC_0531 affects the disulfide bond formation and copper tolerance and deletion of XC_0531 delayed cell growth and reduces EPS production.",L Chen 2017,2017,1 gene,Chen-2017-XC_0531 encodes a c-type cytochrome,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9561,PHI:7255,UniProt,A0A0H2X3T0,GenBank,AAY47612,,,8004,XC_0531,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,putative C-type cytochrome biogenesis protein,,,,reduced virulence,,,,,,,,reduced,,no,dithiothreitol; CuSO4,dithiothreitol: CHEBI:42170; CuSO4: CHEBI:23414,,,,,gene deletion: full; gene complementation,,,YVS,28655353,PubMed,10.1186/s12866-017-1056-9,BMC Microbiol. 2017 Jun 27;17(1):142,lugt@gxu.edu.cn,"Mutant of XC_0531 was deficient in biosynthesis of c-type cytochromes, XC_0531 affects the disulfide bond formation and copper tolerance and deletion of XC_0531 delayed cell growth and reduces EPS production.",L Chen 2017,2017,1 gene,Chen-2017-XC_0531 encodes a c-type cytochrome,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9562,PHI:7256,UniProt,P13445,GenBank,BAA02747,,,DH1,RpoS,,,,,,,562,Escherichia coli,574521,E2348/69,diarrhea,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,28662183,PubMed,10.1371/journal.pone.0180381,PLoS One. 2017 Jun 29;12(6):e0180381,benys@usp.br,"Knockout of rpoS strongly impaired resistance to oxidative, osmotic and acid stress in both E2348/69 and LRT9.",G M S C Mata 2017,2017,1 gene,Mata-2017-RpoS role in virulence and fitness i,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9563,PHI:7256,UniProt,P13445,GenBank,BAA02747,,,DH1,RpoS,,,,,,,562,Escherichia coli,397453,LRT9,diarrhea,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,28662183,PubMed,10.1371/journal.pone.0180381,PLoS One. 2017 Jun 29;12(6):e0180381,benys@usp.br,"Knockout of rpoS strongly impaired resistance to oxidative, osmotic and acid stress in both E2348/69 and LRT9.",G M S C Mata 2017,2017,1 gene,Mata-2017-RpoS role in virulence and fitness i,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9564,PHI:7257,UniProt,A0A068B0X0,GenBank,KJ617041,,,,Rs-scp-1,,,,,,,46012,Radopholus similis,,,blackhead toppling disease,monocots,226677,Anthurium andraeanum (related: oilcloth flower),,,,root,"serine carboxypeptidases, esophageal gland-secreted protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28684768,PubMed,10.1038/s41598-017-05093-7,Sci Rep. 2017 Jul 6;7(1):4815,xiehui@scau.edu.cn,"Compared with water treatment, R.similis treated with RNAi were reduced in number and pathogenicity.",X Huang 2017,2017,1 gene,Huang-2017-Cloning and characterization of the,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9565,PHI:7258,UniProt,P0A4L3,GenBank,CAC99311,,,EGD-e,TrxA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,oxidoreductase,,,,reduced virulence,,,,,,,,wild type,,no,paraquat; H2O2; diamide; cadmium chloride; copper(II) chloride,paraquat: CHEBI:34905; H2O2: CHEBI:16240; diamide: CHEBI:48958; cadmium chloride: CHEBI:35456; copper(II) chloride: CHEBI:49553,,,,,gene deletion: full; gene complementation,,,YVS,28702378,PubMed,10.3389/fcimb.2017.00287,Front Cell Infect Microbiol. 2017 Jun 28;7:287,songhh@zafu.edu.cn,"L. monocytogenes thioredoxin A as a vital cellular reductase was essential for maintaining a highly reducing environment in the bacterial cytosol, which provided a favorable condition for protein folding and activation, and therefore contributed to bacterial virulence and motility.",C Cheng 2017,2017,1 gene,Cheng-2017-Thioredoxin A Is Essential for Moti,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9566,PHI:7258,UniProt,P0A4L3,GenBank,CAC99311,,,EGD-e,TrxA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,liver; kidney,oxidoreductase,,,,reduced virulence,,,,,,,,wild type,,no,paraquat; H2O2; diamide; cadmium chloride; copper(II) chloride,paraquat: CHEBI:34905; H2O2: CHEBI:16240; diamide: CHEBI:48958; cadmium chloride: CHEBI:35456; copper(II) chloride: CHEBI:49553,,,,,gene deletion: full; gene complementation,,,YVS,28702378,PubMed,10.3389/fcimb.2017.00287,Front Cell Infect Microbiol. 2017 Jun 28;7:287,songhh@zafu.edu.cn,"L. monocytogenes thioredoxin A as a vital cellular reductase was essential for maintaining a highly reducing environment in the bacterial cytosol, which provided a favorable condition for protein folding and activation, and therefore contributed to bacterial virulence and motility.",C Cheng 2017,2017,1 gene,Cheng-2017-Thioredoxin A Is Essential for Moti,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9567,PHI:7259,UniProt,Q9P8P2,GenBank,AF223383_1,,,H99,plb1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,lung; lymph node; brain,lysophospholipase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,12595473,PubMed,10.1128/IAI.71.3.1538-1547.2003,Infect Immun. 2003 Mar;71(3):1538-47,ghuff@umich.edu,"Mice infected with either H99 or the plb1rec strain generated a nonprotective inflammatory response with subsequent eosinophilia, while mice infected with the plb1 mutant generated a protective immune response that controlled the infection.",M C Noverr 2003,2003,1 gene,Noverr-2003-Role of PLB1 in pulmonary inflamma,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9568,PHI:7259,UniProt,Q9P8P2,GenBank,AF223383_1,,,H99,plb1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),MH-S cell line,,,macrophage,lysophospholipase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,12595473,PubMed,10.1128/IAI.71.3.1538-1547.2003,Infect Immun. 2003 Mar;71(3):1538-47,ghuff@umich.edu,"Mice infected with either H99 or the plb1rec strain generated a nonprotective inflammatory response with subsequent eosinophilia, while mice infected with the plb1 mutant generated a protective immune response that controlled the infection.",M C Noverr 2003,2003,1 gene,Noverr-2003-Role of PLB1 in pulmonary inflamma,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9569,PHI:7260,UniProt,D2Z001,GenBank,BAI67930,,,RS1000,RipAW,,,,,,PHI:7261,305,Ralstonia solanacearum,,RS1000,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,E3 ubiquitin ligase effector,,,MAPK signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28708051,PubMed,10.1099/mic.0.000495,Microbiology. 2017 Jul;163(7):992-1002,mukaihara@bio-ribs.com,"Transgenic Arabidopsis plants expressing RipAW and RipAR showed increased disease susceptibility, suggesting that RipAW and RipAR contributed to bacterial virulence in plants.",M Nakano 2017,2017,2 genes,Nakano-2017-Ralstonia solanacearum novel E3 ub,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9570,PHI:7261,UniProt,D2Z000,GenBank,BAI67929,,,RS1000,RipAR,,,,,,PHI:7260,305,Ralstonia solanacearum,,RS1000,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,E3 ubiquitin ligase effector,,,MAPK signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28708051,PubMed,10.1099/mic.0.000495,Microbiology. 2017 Jul;163(7):992-1002,mukaihara@bio-ribs.com,"Transgenic Arabidopsis plants expressing RipAW and RipAR showed increased disease susceptibility, suggesting that RipAW and RipAR contributed to bacterial virulence in plants.",M Nakano 2017,2017,2 genes,Nakano-2017-Ralstonia solanacearum novel E3 ub,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9571,PHI:7260,UniProt,D2Z001,GenBank,BAI67930,,,RS1000,RipAW,,,,,,PHI:7261,305,Ralstonia solanacearum,,RS1000,wilt,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,E3 ubiquitin ligase effector,,,MAPK signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28708051,PubMed,10.1099/mic.0.000495,Microbiology. 2017 Jul;163(7):992-1002,mukaihara@bio-ribs.com,"Transgenic Arabidopsis plants expressing RipAW and RipAR showed increased disease susceptibility, suggesting that RipAW and RipAR contributed to bacterial virulence in plants.",M Nakano 2017,2017,2 genes,Nakano-2017-Ralstonia solanacearum novel E3 ub,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9572,PHI:7261,UniProt,D2Z000,GenBank,BAI67929,,,RS1000,RipAR,,,,,,PHI:7260,305,Ralstonia solanacearum,,RS1000,wilt,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,E3 ubiquitin ligase effector,,,MAPK signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28708051,PubMed,10.1099/mic.0.000495,Microbiology. 2017 Jul;163(7):992-1002,mukaihara@bio-ribs.com,"Transgenic Arabidopsis plants expressing RipAW and RipAR showed increased disease susceptibility, suggesting that RipAW and RipAR contributed to bacterial virulence in plants.",M Nakano 2017,2017,2 genes,Nakano-2017-Ralstonia solanacearum novel E3 ub,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9573,PHI:7262,UniProt,P0A9Y9,GenBank,AAC06037,,,3027,cspC,,,,,,PHI:7263,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain UMR1,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide; polymyxin B,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309,,,,,gene deletion: full,,,YVS,28611217,PubMed,10.1073/pnas.1620772114,Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6824-6829,joerg.vogel@uni-wuerzburg.de,"Phenotypic assays in vitro demonstrated a crucial role for these proteins in membrane stress, motility and biofilm formation.",C Michaux 2017,2017,2 genes,Michaux-2017-RNA target profiles direct the di,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9574,PHI:7263,UniProt,A0A0F6AYC2,GenBank,ACY87244,,,14028S,cspE,,,,,,PHI:7262,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain UMR1,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide; polymyxin B,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309,,,,,gene deletion: full,,,YVS,28611217,PubMed,10.1073/pnas.1620772114,Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6824-6829,joerg.vogel@uni-wuerzburg.de,"Phenotypic assays in vitro demonstrated a crucial role for these proteins in membrane stress, motility and biofilm formation.",C Michaux 2017,2017,2 genes,Michaux-2017-RNA target profiles direct the di,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9575,PHI:7262,UniProt,P0A9Y9,GenBank,AAC06037,,,3027,cspC,,,,,,PHI:7263,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain UMR1,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,cold shock protein,,,,loss of pathogenicity,,,,,,,,,,no,hydrogen peroxide; polymyxin B,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309,,,,,gene deletion: full,,,YVS,28611217,PubMed,10.1073/pnas.1620772114,Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6824-6829,joerg.vogel@uni-wuerzburg.de,"Phenotypic assays in vitro demonstrated a crucial role for these proteins in membrane stress, motility and biofilm formation.",C Michaux 2017,2017,2 genes,Michaux-2017-RNA target profiles direct the di,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9576,PHI:7263,UniProt,A0A0F6AYC2,GenBank,ACY87244,,,14028S,cspE,,,,,,PHI:7262,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain UMR1,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,cold shock protein,,,,loss of pathogenicity,,,,,,,,,,no,hydrogen peroxide; polymyxin B,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309,,,,,gene deletion: full,,,YVS,28611217,PubMed,10.1073/pnas.1620772114,Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6824-6829,joerg.vogel@uni-wuerzburg.de,"Phenotypic assays in vitro demonstrated a crucial role for these proteins in membrane stress, motility and biofilm formation.",C Michaux 2017,2017,2 genes,Michaux-2017-RNA target profiles direct the di,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9577,PHI:7262,UniProt,P0A9Y9,GenBank,AAC06037,,,3027,cspC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain UMR1,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,cold shock protein,,,,unaffected pathogenicity,,,,,,,,,,no,hydrogen peroxide; polymyxin B,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309,,,,,gene deletion: full,,,YVS,28611217,PubMed,10.1073/pnas.1620772114,Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6824-6829,joerg.vogel@uni-wuerzburg.de,"Phenotypic assays in vitro demonstrated a crucial role for these proteins in membrane stress, motility and biofilm formation.",C Michaux 2017,2017,2 genes,Michaux-2017-RNA target profiles direct the di,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9578,PHI:7263,UniProt,A0A0F6AYC2,GenBank,ACY87244,,,14028S,cspE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain UMR1,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,cold shock protein,,,,unaffected pathogenicity,,,,,,,,,,no,hydrogen peroxide; polymyxin B,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309,,,,,gene deletion: full,,,YVS,28611217,PubMed,10.1073/pnas.1620772114,Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6824-6829,joerg.vogel@uni-wuerzburg.de,"Phenotypic assays in vitro demonstrated a crucial role for these proteins in membrane stress, motility and biofilm formation.",C Michaux 2017,2017,2 genes,Michaux-2017-RNA target profiles direct the di,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9579,PHI:7264,UniProt,P14916,GenBank,BAA84532,,,HPK5,UreA,,,,,,,210,Helicobacter pylori,,X47,gastric infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,stomach,hydrolase,,,,reduced virulence,,,,,,,,,,no,doxycycline; anhydrotetracycline,doxycycline: CHEBI:50845; anhydrotetracycline: CHEBI:17146,,,,,gene mutation,,,YVS,28644872,PubMed,10.1371/journal.ppat.1006464,PLoS Pathog. 2017 Jun 23;13(6):e1006464,aleksandra.debowski@uwa.edu.au,Strong selective pressure on the bacteria for continuous urease expression was further demonstrated by the emergence of escape mutants that successfully repopulated the mouse stomach six weeks after genetic silencing of urease was initiated.,A W Debowski 2017,2017,1 gene,Debowski-2017-Helicobacter pylori gene silenci,BATCH_071A,2017-07-01,MC,,,,,,,,,,,,,
,,Record 9580,PHI:7265,UniProt,Q79LY0,GenBank,AAO43976,,,DC3000,HopPtoD2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector type III secreted protein,,,MAPK pathways,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,12828636,PubMed,10.1046/j.1365-2958.2003.03588.x,Mol Microbiol. 2003 Jul;49(2):377-87,jalfano2@unl.edu,DC3000 hopPtoD2 mutants were slightly reduced in their ability to multiply in planta and displayed an enhanced ability to elicit an HR.,A Espinosa 2003,2003,1 gene,Espinosa-2003-The Pseudomonas syringae type II,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9581,PHI:7265,UniProt,Q79LY0,GenBank,AAO43976,,,DC3000,HopPtoD2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,effector type III secreted protein,,,MAPK pathways,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,12828636,PubMed,10.1046/j.1365-2958.2003.03588.x,Mol Microbiol. 2003 Jul;49(2):377-87,jalfano2@unl.edu,DC3000 hopPtoD2 mutants were slightly reduced in their ability to multiply in planta and displayed an enhanced ability to elicit an HR.,A Espinosa 2003,2003,1 gene,Espinosa-2003-The Pseudomonas syringae type II,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9582,PHI:7265,UniProt,Q79LY0,GenBank,AAO43976,,,DC3000,HopPtoD2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,fruit,effector type III secreted protein,,,MAPK pathways,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,12828636,PubMed,10.1046/j.1365-2958.2003.03588.x,Mol Microbiol. 2003 Jul;49(2):377-87,jalfano2@unl.edu,DC3000 hopPtoD2 mutants were slightly reduced in their ability to multiply in planta and displayed an enhanced ability to elicit an HR.,A Espinosa 2003,2003,1 gene,Espinosa-2003-The Pseudomonas syringae type II,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9583,PHI:7265,UniProt,Q79LY0,GenBank,AAO43976,,,DC3000,HopPtoD2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,effector type III secreted protein,,,MAPK pathways,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,12828636,PubMed,10.1046/j.1365-2958.2003.03588.x,Mol Microbiol. 2003 Jul;49(2):377-87,jalfano2@unl.edu,DC3000 hopPtoD2 mutants were slightly reduced in their ability to multiply in planta and displayed an enhanced ability to elicit an HR.,A Espinosa 2003,2003,1 gene,Espinosa-2003-The Pseudomonas syringae type II,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9584,PHI:7266,UniProt,Q6TKR8,GenBank,AAQ97593,,,,avrRxo1,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,type III secreted effector,,,metabolic pathway,effector (plant avirulence determinant),,,,,,,,,,no,menadione,menadione: CHEBI:28869,,,,,gene mutation,,,YVS,28628666,PubMed,10.1371/journal.ppat.1006442,PLoS Pathog. 2017 Jun 19;13(6):e1006442,lindsay.triplett@CT.gov,"Mutation of the catalytic aspartic acid residue D193 abolished AvrRxo1 kinase activity and several phenotypes of AvrRxo1, including toxicity in yeast, bacteria, and plants, suppression of the flg22-triggered ROS burst and ability to trigger an R gene-mediated hypersensitive response.",T Shidore 2017,2017,1 gene,Shidore-2017-The effector AvrRxo1 phosphorylat,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9585,PHI:7266,UniProt,Q6TKR8,GenBank,AAQ97593,,,,avrRxo1,,,,,,,347,Xanthomonas oryzae,1423890,pv. oryzicola strain MAI10,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,type III secreted effector,,,metabolic pathway,effector (plant avirulence determinant),,,,,,,,,,no,menadione,menadione: CHEBI:28869,,,,,gene mutation,,,YVS,28628666,PubMed,10.1371/journal.ppat.1006442,PLoS Pathog. 2017 Jun 19;13(6):e1006442,lindsay.triplett@CT.gov,"Mutation of the catalytic aspartic acid residue D193 abolished AvrRxo1 kinase activity and several phenotypes of AvrRxo1, including toxicity in yeast, bacteria, and plants, suppression of the flg22-triggered ROS burst and ability to trigger an R gene-mediated hypersensitive response.",T Shidore 2017,2017,1 gene,Shidore-2017-The effector AvrRxo1 phosphorylat,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9586,PHI:7266,UniProt,Q6TKR8,GenBank,AAQ97593,,,,avrRxo1,,,,,,,347,Xanthomonas oryzae,1009853,X11-5A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,type III secreted effector,,,metabolic pathway,effector (plant avirulence determinant),,,,,,,,,,no,menadione,menadione: CHEBI:28869,,,,,gene mutation,,,YVS,28628666,PubMed,10.1371/journal.ppat.1006442,PLoS Pathog. 2017 Jun 19;13(6):e1006442,lindsay.triplett@CT.gov,"Mutation of the catalytic aspartic acid residue D193 abolished AvrRxo1 kinase activity and several phenotypes of AvrRxo1, including toxicity in yeast, bacteria, and plants, suppression of the flg22-triggered ROS burst and ability to trigger an R gene-mediated hypersensitive response.",T Shidore 2017,2017,1 gene,Shidore-2017-The effector AvrRxo1 phosphorylat,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9587,PHI:7267,UniProt,I1RZQ6,GenBank,CEF75210,,,PH-1,PKR,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,scab (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,flower; kernel; spikelet,regulatory subunit of PKA,,,cAMP-PKA pathway,reduced virulence,yes,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28665481,PubMed,10.1111/mpp.12576,Mol Plant Pathol. 2017 Jun 30,wangchenfang@nwafu.edu.cn,"PKR was important for regulating hyphal growth, reproduction, pathogenesis and DON production.",C Li 2017,2017,1 gene,Li-2017-The PKR regulatory subunit of PKA is i,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9588,PHI:7267,UniProt,I1RZQ6,GenBank,CEF75210,,,PH-1,PKR,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,scab (wheat),monocots,4577,Zea mays (related: maize),subsp. mays,,,corn silk,regulatory subunit of PKA,,,cAMP-PKA pathway,reduced virulence,yes,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28665481,PubMed,10.1111/mpp.12576,Mol Plant Pathol. 2017 Jun 30,wangchenfang@nwafu.edu.cn,"PKR was important for regulating hyphal growth, reproduction, pathogenesis and DON production.",C Li 2017,2017,1 gene,Li-2017-The PKR regulatory subunit of PKA is i,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9589,PHI:7268,UniProt,O69690,GenBank,CCP46549,,,H37Rv,Rv3723/LucA,,ΔlucA::hyg,,Rv0199/OmamA; Rv0177/Mam1C; Rv3492/Mam4A,UniProt: O53650; GenBank: CCP42927; UniProt: O07421; GenBank: CCP42903; UniProt: I6YGA5; Gen,,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bone marrow-derived macrophage,lipid uptake coordinator,,,lipid metabolic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28708968,PubMed,10.7554/eLife.26969,Elife. 2017 Jun 27;6. pii: e26969,bcv8@cornell.edu,LucA facilitated the fatty acid and cholesterol uptake in Mtb by stabilizing protein subunits of the Mce1 and Mce4 transporters.,E V Nazarova 2017,2017,1 gene,Nazarova-2017-Rv3723_LucA coordinates fatty ac,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9590,PHI:7268,UniProt,O69690,GenBank,CCP46549,,,H37Rv,Rv3723/LucA,,ΔlucA::hyg,,Rv0199/OmamA; Rv0177/Mam1C; Rv3492/Mam4A,UniProt: O53650; GenBank: CCP42927; UniProt: O07421; GenBank: CCP42903; UniProt: I6YGA5; Gen,,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,primates,9606,Homo sapiens (related: human),,,,macrophage,lipid uptake coordinator,,,lipid metabolic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28708968,PubMed,10.7554/eLife.26969,Elife. 2017 Jun 27;6. pii: e26969,bcv8@cornell.edu,LucA facilitated the fatty acid and cholesterol uptake in Mtb by stabilizing protein subunits of the Mce1 and Mce4 transporters.,E V Nazarova 2017,2017,1 gene,Nazarova-2017-Rv3723_LucA coordinates fatty ac,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9591,PHI:7268,UniProt,O69690,GenBank,CCP46549,,,H37Rv,Rv3723/LucA,,ΔlucA::hyg,,Rv0199/OmamA; Rv0177/Mam1C; Rv3492/Mam4A,UniProt: O53650; GenBank: CCP42927; UniProt: O07421; GenBank: CCP42903; UniProt: I6YGA5; Gen,,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),B6;129S7-Dbh<tm1Rpa>/Rpa,,,lung,lipid uptake coordinator,,,lipid metabolic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28708968,PubMed,10.7554/eLife.26969,Elife. 2017 Jun 27;6. pii: e26969,bcv8@cornell.edu,LucA facilitated the fatty acid and cholesterol uptake in Mtb by stabilizing protein subunits of the Mce1 and Mce4 transporters.,E V Nazarova 2017,2017,1 gene,Nazarova-2017-Rv3723_LucA coordinates fatty ac,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9592,PHI:7269,UniProt,O54305,GenBank,CAB09344,,,,ssrB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28704543,PubMed,10.1371/journal.ppat.1006497,PLoS Pathog. 2017 Jul 13;13(7):e1006497,victor@ibt.unam.mx,SsrB negatively regulates SPI-1 during the course of the intestinal infection of S. Typhimurium in a mouse model. SsrB simultaneously represses SPI-1 and activates SPI-2 inside RAW264.7 mouse macrophages.,D Pérez-Morales 2017,2017,3 genes,Perez-Morales-2017-The transcriptional regulat,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9593,PHI:7270,UniProt,P0CL08,GenBank,AAL21755,,,LT2; SGSC 1412; ATCC 700720,hilD,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28704543,PubMed,10.1371/journal.ppat.1006497,PLoS Pathog. 2017 Jul 13;13(7):e1006497,victor@ibt.unam.mx,SsrB negatively regulates SPI-1 during the course of the intestinal infection of S. Typhimurium in a mouse model.,D Pérez-Morales 2017,2017,3 genes,Perez-Morales-2017-The transcriptional regulat,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9594,PHI:7271,UniProt,P0A2R2,GenBank,AAB96639,,,LT2,flhDC,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28704543,PubMed,10.1371/journal.ppat.1006497,PLoS Pathog. 2017 Jul 13;13(7):e1006497,victor@ibt.unam.mx,SsrB negatively regulates SPI-1 during the course of the intestinal infection of S. Typhimurium in a mouse model.,D Pérez-Morales 2017,2017,3 genes,Perez-Morales-2017-The transcriptional regulat,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9595,PHI:7272,,no data found,GenBank,SPA0021 sRNA,,,,pesA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,infection,primates,9606,Homo sapiens (related: human),IB3-1 cell line,,,bronchial epithelial cell line,pathogenicity island-encoded sRNA A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28665976,PubMed,10.1371/journal.pone.0180386,PLoS One.2017 Jun 30;12(6):e0180386,silvia.ferrara@unimi.it,The deletion of pesA gene resulted in increased sensitivity to UV irradiation and to the fluoroquinolone antibiotic ciprofloxacin.,S Ferrara 2017,2017,1 gene,Ferrara-2017-The PAPI-1 pathogenicity island-e,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9596,PHI:7273,UniProt,G4N549,GenBank,EHA52960,,,70-15,Pmp1,chromosome 3,,,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,"putative protein phosphatase, novel virulence factor",,,MAPK signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28706003,PubMed,10.1074/mcp.M116.066670,Mol Cell Proteomics. 2017 Jul 13. pii: mcp.M116.066670,pengyl@cau.edu.cn,"Phosphorylation of Pmk1, Mps1 was significantly increased in the Δpmp1 mutant and and decreased in the site-directed dominant PMP1S240D allele mutant, Mps1 and Pmk1 are important for conidiation and virulence. Mps1, MAP kinase required for cell wall integrity and appressorium formation.",R Wang 2017,2017,1 gene,Wang-2017-Phosphorylation-Mediated Regulatory,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9597,PHI:7273,UniProt,G4N549,GenBank,EHA52960,,,70-15,Pmp1,chromosome 3,,,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,"putative protein phosphatase, novel virulence factor",,,MAPK signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28706003,PubMed,10.1074/mcp.M116.066670,Mol Cell Proteomics. 2017 Jul 13. pii: mcp.M116.066670,pengyl@cau.edu.cn,"Phosphorylation of Pmk1, Mps1 was significantly increased in the Δpmp1 mutant and and decreased in the site-directed dominant PMP1S240D allele mutant, Mps1 and Pmk1 are important for conidiation and virulence. Mps1, MAP kinase required for cell wall integrity and appressorium formation.",R Wang 2017,2017,1 gene,Wang-2017-Phosphorylation-Mediated Regulatory,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9598,PHI:7273,UniProt,G4N549,GenBank,EHA52960,,,70-15,Pmp1,chromosome 3,PMP1S240D,,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,"putative protein phosphatase, novel virulence factor",,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,28706003,PubMed,10.1074/mcp.M116.066670,Mol Cell Proteomics. 2017 Jul 13. pii: mcp.M116.066670,pengyl@cau.edu.cn,"Phosphorylation of Pmk1, Mps1 was significantly increased in the Δpmp1 mutant and and decreased in the site-directed dominant PMP1S240D allele mutant, Mps1 and Pmk1 are important for conidiation and virulence. Mps1, MAP kinase required for cell wall integrity and appressorium formation.",R Wang 2017,2017,1 gene,Wang-2017-Phosphorylation-Mediated Regulatory,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9599,PHI:7273,UniProt,G4N549,GenBank,EHA52960,,,70-15,Pmp1,chromosome 3,PMP1S240D,,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,"putative protein phosphatase, novel virulence factor",,,MAPK signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,28706003,PubMed,10.1074/mcp.M116.066670,Mol Cell Proteomics. 2017 Jul 13. pii: mcp.M116.066670,pengyl@cau.edu.cn,"Phosphorylation of Pmk1, Mps1 was significantly increased in the Δpmp1 mutant and and decreased in the site-directed dominant PMP1S240D allele mutant, Mps1 and Pmk1 were important for conidiation and virulence.",R Wang 2017,2017,1 gene,Wang-2017-Phosphorylation-Mediated Regulatory,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9600,PHI:7274,UniProt,Q9C410,GenBank,AF321521_1,,,ATCC 10261,NRG1,,,,,,,5476,Candida albicans,,CAF2-1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; brain; spleen,"negative regulator of filamentation, transcriptional repressor of hypha-specific gene",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,14555488,PubMed,10.1128/EC.2.5.1053-1060.2003,Eukaryot Cell. 2003 Oct;2(5):1053-60,saville@uthscsa.edu,"Mice injected with the modified strain under conditions permitting hyphal development succumbed to the infection, whereas all of the animals injected under conditions that inhibited this transition survived.",S P Saville 2003,2003,1 gene,Saville-2003-Engineered control of cell morpho,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9601,PHI:7275,UniProt,Q01928,GenBank,AAA67875,,,race 1,Pep-13,,W231T or P234A,,,,,67593,Phytophthora sojae,,,stem rot (soybean); root rot (soybean),eudicots,4113,Solanum tuberosum (related: potato),,,,leaf,glycoprotein elicitor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,12485989,PubMed,10.1093/emboj/cdf667,EMBO J. 2002 Dec 16;21(24):6681-8,tnuernbe@ipb-halle.de,The data demonstarted that amino acid residues important for transglutaminase (Tgase) activity were identical to those necessary to elicit defense reactions in parsley protoplasts.,F Brunner 2002,2002,1 gene,"Brunner-2002-Pep-13, a plant defense-inducing",BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9602,PHI:7275,UniProt,Q01928,GenBank,AAA67875,,,race 1,Pep-13,,W231T or P234A,,,,,67593,Phytophthora sojae,,,stem rot (soybean); root rot (soybean),eudicots,4043,Petroselinum crispum (related: parsley),,,,,glycoprotein elicitor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,12485989,PubMed,10.1093/emboj/cdf667,EMBO J. 2002 Dec 16;21(24):6681-8,tnuernbe@ipb-halle.de,The data demonstarted that amino acid residues important for transglutaminase (Tgase) activity were identical to those necessary to elicit defense reactions in parsley protoplasts.,F Brunner 2002,2002,1 gene,"Brunner-2002-Pep-13, a plant defense-inducing",BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9603,PHI:7275,UniProt,Q01928,GenBank,AAA67875,,,race 1,Pep-13,,Y241A,,,,,67593,Phytophthora sojae,,,stem rot (soybean); root rot (soybean),eudicots,4043,Petroselinum crispum (related: parsley),,,,,glycoprotein elicitor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,12485989,PubMed,10.1093/emboj/cdf667,EMBO J. 2002 Dec 16;21(24):6681-8,tnuernbe@ipb-halle.de,The data demonstarted that amino acid residues important for transglutaminase (Tgase) activity were identical to those necessary to elicit defense reactions in parsley protoplasts.,F Brunner 2002,2002,1 gene,"Brunner-2002-Pep-13, a plant defense-inducing",BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9604,PHI:7276,UniProt,Q8XRI1,GenBank,CAD18004,,,GMI1000,hpaB,,,,RipG1; RipG4; RipG5; RipO1; RipP1; RipAF1; RipAK; RipAW; RipTPS,UniProt: Q8XRE0; GenBank: CAD18065; UniProt: Q8XYF8; GenBank: CAD15502; UniProt: Q8XYF7; Gen,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Marmande,,,root,"type III chaperones, hypersensitive response and pathogenicity associated protein",,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28687734,PubMed,10.1038/s41598-017-04853-9,Sci Rep. 2017 Jul 7;7(1):4879,fabienne.vailleau@inra.fr,The hpaB gene from X. campestris pv. vesicatoria could complement the R. solanacearum hpaB mutant for HR elicitation on tobacco plants.,F Lonjon 2017,2017,2 genes,Lonjon-2017-HpaB-Dependent Secretion of Type I,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9605,PHI:7277,UniProt,Q8XRI3,GenBank,CAD17999,,,GMI1000,hpaD,,,,RipG4; RipO1; RipP1; RipAF1; RipAV; RipAW; RipTPS; RipTAL,UniProt: Q8XYF8; GenBank: CAD15502; UniProt: Q8XSZ4; GenBank: CAD17474; UniProt: Q8Y164; Gen,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Marmande,,,root,"type III chaperones, hypersensitive response and pathogenicity associated protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28687734,PubMed,10.1038/s41598-017-04853-9,Sci Rep. 2017 Jul 7;7(1):4879,fabienne.vailleau@inra.fr,The hpaB gene from X. campestris pv. vesicatoria could complement the R. solanacearum hpaB mutant for HR elicitation on tobacco plants.,F Lonjon 2017,2017,2 genes,Lonjon-2017-HpaB-Dependent Secretion of Type I,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9606,PHI:7276,UniProt,Q8XRI1,GenBank,CAD18004,,,GMI1000,hpaB,,,,RipG1; RipG4; RipG5; RipO1; RipP1; RipAF1; RipAK; RipAW; RipTPS,UniProt: Q8XRE0; GenBank: CAD18065; UniProt: Q8XYF8; GenBank: CAD15502; UniProt: Q8XYF7; Gen,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,"type III chaperones, hypersensitive response and pathogenicity associated protein",,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28687734,PubMed,10.1038/s41598-017-04853-9,Sci Rep. 2017 Jul 7;7(1):4879,fabienne.vailleau@inra.fr,The hpaB gene from X. campestris pv. vesicatoria could complement the R. solanacearum hpaB mutant for HR elicitation on tobacco plants.,F Lonjon 2017,2017,2 genes,Lonjon-2017-HpaB-Dependent Secretion of Type I,BATCH_071B,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9607,PHI:7278,,no data found,,,,,,PCN,,,,,,,121759,Paracoccidioides brasiliensis,502780,18,paracoccidioidomycosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,multidomain fungal protein with both lectin and enzymatic activities,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28720727,PubMed,10.1128/mBio.00537-17,MBio.2017 Jul 18;8(4). pii: e00537-17,mcrbarre@fmrp.usp.br.,"PCN silencing led to the aggregation of fungal cells, blocked the morphological yeast-to-mycelium transition, and rendered the yeast less resistant to macrophage fungicidal activity.",F F Fernandes 2017,2017,1 gene,Fernandes-2017-Impact of Paracoccin Gene Silen,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9608,PHI:7279,UniProt,J4VTY1,GenBank,EJP61995,,,ARSEF 2860,mpk3,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitogen-activated protein kinase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl; sorbitol; Congo red; H2O2; menadione; fludioxonil,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,28766034,PubMed,10.1007/s00253-017-8434-y,Appl Microbiol Biotechnol.2017 Aug 2,mgfeng@zju.edu.cn,Mpk3 collaborates with Hog1 only in response to heat shock and functions in sustaining the pest control potential of B. bassiana.,J Liu 2017,2017,2 genes,Liu-2017-The Hog1-like MAPK Mpk3 collaborates,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9609,PHI:7280,UniProt,Q6PWX2,GenBank,AAS77871,,,,hog1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitogen-activated protein kinase,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,NaCl; sorbitol; Congo red; H2O2; menadione; fludioxonil,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full,,,YVS,28766034,PubMed,10.1007/s00253-017-8434-y,Appl Microbiol Biotechnol.2017 Aug 2,mgfeng@zju.edu.cn,Mpk3 collaborates with Hog1 only in response to heat shock and functions in sustaining the pest control potential of B. bassiana.,J Liu 2017,2017,2 genes,Liu-2017-The Hog1-like MAPK Mpk3 collaborates,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9610,PHI:7279,UniProt,J4VTY1,GenBank,EJP61995,,,ARSEF 2860,mpk3,,,,,,PHI:7280,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitogen-activated protein kinase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl; sorbitol; Congo red; H2O2; menadione; fludioxonil,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full,,,YVS,28766034,PubMed,10.1007/s00253-017-8434-y,Appl Microbiol Biotechnol.2017 Aug 2,mgfeng@zju.edu.cn,Mpk3 collaborates with Hog1 only in response to heat shock and functions in sustaining the pest control potential of B. bassiana.,J Liu 2017,2017,2 genes,Liu-2017-The Hog1-like MAPK Mpk3 collaborates,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9611,PHI:7280,UniProt,Q6PWX2,GenBank,AAS77871,,,,hog1,,,,,,PHI:7279,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitogen-activated protein kinase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl; sorbitol; Congo red; H2O2; menadione; fludioxonil,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full,,,YVS,28766034,PubMed,10.1007/s00253-017-8434-y,Appl Microbiol Biotechnol.2017 Aug 2,mgfeng@zju.edu.cn,Mpk3 collaborates with Hog1 only in response to heat shock and functions in sustaining the pest control potential of B. bassiana.,J Liu 2017,2017,2 genes,Liu-2017-The Hog1-like MAPK Mpk3 collaborates,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9612,PHI:7281,UniProt,A0A192GP70,GenBank,ANK58184,,,,PsINV,,,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,invertase,,,,reduced virulence,,,,,,reduced,,,reduced,no,,,,,,,altered gene expression / gene regulation: silencing: gene complementation,,,YVS,28744865,PubMed,10.1111/nph.14666,New Phytol.2017 Sep;215(4):1548-1561,kangzs@nwafu.edu.cn,Pst invertase plays a pivotal role in this plant-pathogen interaction probably by boosting sucrose hydrolysis to secure the pathogen's sugar absorption.,Q Chang 2017,2017,1 gene,Chang-2017-A unique invertase is important for,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9613,PHI:7282,UniProt,G1X9G7,GenBank,EGX50199,,,ATCC 24927,76g274,,,,,,,2813651,Orbilia oligospora,756982,CBS 115.81,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,C2H2-type transcription factor,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,H2O2; NaCl; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,YVS,28717216,PubMed,10.1038/s41598-017-06075-5,Sci Rep.2017 Jul 17;7(1):5640,jinkui960@ynu.edu.cn,"Phenotypic analysis found that the deletion mutant did not differ significantly from the WT in growth, resistance to NaCl, SDS and H2O2, Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021. proteolytic activity, as well as trap formation, but the mutant had sharply reduced sporulation yields.",D Jiang 2017,2017,1 gene,Jiang-2017-Random mutagenesis analysis and ide,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9614,PHI:7283,UniProt,I1S2L3,MIPS,FGSG_11011,,,PH-1,Pg1,chromosome 3,,,,,,5518,Fusarium graminearum,,3827,Fusarium head blight,eudicots,3847,Glycine max (related: soybean),cv. Demetra,,,seedling,endo-polygalacturonase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9615,PHI:7284,,no data found,MIPS,FGSG_17662,,,,xyr1,,,,,,,5518,Fusarium graminearum,,3827,Fusarium head blight,eudicots,3847,Glycine max (related: soybean),cv. Demetra,,,seedling,major regulator of xylanase production,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9616,PHI:7283,UniProt,I1S2L3,MIPS,FGSG_11011,,,PH-1,Pg1,chromosome 3,,,,,,5518,Fusarium graminearum,,3827,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,endo-polygalacturonase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9617,PHI:7284,,no data found,MIPS,FGSG_17662,,,,xyr1,,,,,,,5518,Fusarium graminearum,,3827,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,major regulator of xylanase production,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9618,PHI:7283,UniProt,I1S2L3,MIPS,FGSG_11011,,,PH-1,Pg1,chromosome 3,,,,,,5518,Fusarium graminearum,,3827,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,endo-polygalacturonase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9619,PHI:7284,,no data found,MIPS,FGSG_17662,,,,xyr1,,,,,,,5518,Fusarium graminearum,,3827,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,major regulator of xylanase production,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9620,PHI:7283,UniProt,I1S2L3,MIPS,FGSG_11011,,,PH-1,Pg1,chromosome 3,,,,,PHI:7284,5518,Fusarium graminearum,,3827,Fusarium head blight,eudicots,3847,Glycine max (related: soybean),cv. Demetra,,,seedling,endo-polygalacturonase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9621,PHI:7284,,no data found,MIPS,FGSG_17662,,,,xyr1,,,,,,PHI:7283,5518,Fusarium graminearum,,3827,Fusarium head blight,eudicots,3847,Glycine max (related: soybean),cv. Demetra,,,seedling,major regulator of xylanase production,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9622,PHI:7283,UniProt,I1S2L3,MIPS,FGSG_11011,,,PH-1,Pg1,chromosome 3,,,,,PHI:7284,5518,Fusarium graminearum,,3827,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,endo-polygalacturonase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9623,PHI:7284,,no data found,MIPS,FGSG_17662,,,,xyr1,,,,,,PHI:7283,5518,Fusarium graminearum,,3827,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,major regulator of xylanase production,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9624,PHI:7283,UniProt,I1S2L3,MIPS,FGSG_11011,,,PH-1,Pg1,chromosome 3,,,,,PHI:7284,5518,Fusarium graminearum,,3827,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,endo-polygalacturonase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9625,PHI:7284,,no data found,MIPS,FGSG_17662,,,,xyr1,,,,,,PHI:7283,5518,Fusarium graminearum,,3827,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,major regulator of xylanase production,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,28800710,PubMed,10.1094/MPMI-07-17-0179-R,MolPlantMicrobe Interact.2017 Aug 11,luca.sella@unipd.it,"The concurrent presence of endo-polygalacturonase, xylanase and cellulase activities was necessary for full virulence.",M C Paccanaro 2017,2017,2 genes,Paccanaro-2017-Synergistic effect of different,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9626,PHI:7285,UniProt,W7MLS8,GenBank,EWG52036,,,7600,FvCP01,chromosome 11,,,,,,117187,Fusarium verticillioides,,M-3125,stalk rot (maize); ear rot (maize); seedling blight (maize),monocots,4577,Zea mays (related: maize),cv. Silver Queen,,,shoot,catalase-peroxidase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28802018,PubMed,10.1111/mpp.12591,Mol Plant Pathol.2017 Aug 12,anthony.glenn@ars.usda.gov,Both ΔFvCP01 and ΔFvCP02 were more sensitive to H2O2 than the wild type in vitro and the ΔFvCP01/ΔFvCP02 double deletion were the most sensitive to H2O2.,S Gao 2017,2017,2 genes,Gao-2017-Characterization of two catalase-pero,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9627,PHI:7286,UniProt,W7NEP8,GenBank,EWG54767,,,7600,FvCP02,chromosome 11,,,,,,117187,Fusarium verticillioides,,M-3125,stalk rot (maize); ear rot (maize); seedling blight (maize),monocots,4577,Zea mays (related: maize),cv. Silver Queen,,,shoot,catalase-peroxidase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28802018,PubMed,10.1111/mpp.12591,Mol Plant Pathol.2017 Aug 12,anthony.glenn@ars.usda.gov,Both ΔFvCP01 and ΔFvCP02 were more sensitive to H2O2 than the wild type in vitro and the ΔFvCP01/ΔFvCP02 double deletion were the most sensitive to H2O2.,S Gao 2017,2017,2 genes,Gao-2017-Characterization of two catalase-pero,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9628,PHI:7285,UniProt,W7MLS8,GenBank,EWG52036,,,7600,FvCP01,chromosome 11,,,,,,117187,Fusarium verticillioides,,M-3125,stalk rot (maize); ear rot (maize); seedling blight (maize),monocots,4577,Zea mays (related: maize),cv. Silver Queen,,,shoot,catalase-peroxidase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28802018,PubMed,10.1111/mpp.12591,Mol Plant Pathol.2017 Aug 12,anthony.glenn@ars.usda.gov,Both ΔFvCP01 and ΔFvCP02 were more sensitive to H2O2 than the wild type in vitro and the ΔFvCP01/ΔFvCP02 double deletion were the most sensitive to H2O2.,S Gao 2017,2017,2 genes,Gao-2017-Characterization of two catalase-pero,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9629,PHI:7286,UniProt,W7NEP8,GenBank,EWG54767,,,7600,FvCP02,chromosome 11,,,,,,117187,Fusarium verticillioides,,M-3125,stalk rot (maize); ear rot (maize); seedling blight (maize),monocots,4577,Zea mays (related: maize),cv. Silver Queen,,,shoot,catalase-peroxidase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28802018,PubMed,10.1111/mpp.12591,Mol Plant Pathol.2017 Aug 12,anthony.glenn@ars.usda.gov,Both ΔFvCP01 and ΔFvCP02 were more sensitive to H2O2 than the wild type in vitro and the ΔFvCP01/ΔFvCP02 double deletion were the most sensitive to H2O2.,S Gao 2017,2017,2 genes,Gao-2017-Characterization of two catalase-pero,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9630,PHI:7285,UniProt,W7MLS8,GenBank,EWG52036,,,7600,FvCP01,chromosome 11,,,,,,117187,Fusarium verticillioides,,A00999,stalk rot (maize); ear rot (maize); seedling blight (maize),monocots,4577,Zea mays (related: maize),cv. Silver Queen,,,shoot,catalase-peroxidase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28802018,PubMed,10.1111/mpp.12591,Mol Plant Pathol.2017 Aug 12,anthony.glenn@ars.usda.gov,Both ΔFvCP01 and ΔFvCP02 were more sensitive to H2O2 than the wild type in vitro and the ΔFvCP01/ΔFvCP02 double deletion were the most sensitive to H2O2.,S Gao 2017,2017,2 genes,Gao-2017-Characterization of two catalase-pero,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9631,PHI:7286,UniProt,W7NEP8,GenBank,EWG54767,,,7600,FvCP02,chromosome 11,,,,,,117187,Fusarium verticillioides,,A00999,stalk rot (maize); ear rot (maize); seedling blight (maize),monocots,4577,Zea mays (related: maize),cv. Silver Queen,,,shoot,catalase-peroxidase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28802018,PubMed,10.1111/mpp.12591,Mol Plant Pathol.2017 Aug 12,anthony.glenn@ars.usda.gov,Both ΔFvCP01 and ΔFvCP02 were more sensitive to H2O2 than the wild type in vitro and the ΔFvCP01/ΔFvCP02 double deletion were the most sensitive to H2O2.,S Gao 2017,2017,2 genes,Gao-2017-Characterization of two catalase-pero,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9632,PHI:7285,UniProt,W7MLS8,GenBank,EWG52036,,,7600,FvCP01,chromosome 11,,,,,PHI:7286,117187,Fusarium verticillioides,,A00999,stalk rot (maize); ear rot (maize); seedling blight (maize),monocots,4577,Zea mays (related: maize),cv. Silver Queen,,,shoot,catalase-peroxidase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28802018,PubMed,10.1111/mpp.12591,Mol Plant Pathol.2017 Aug 12,anthony.glenn@ars.usda.gov,Both ΔFvCP01 and ΔFvCP02 were more sensitive to H2O2 than the wild type in vitro and the ΔFvCP01/ΔFvCP02 double deletion were the most sensitive to H2O2.,S Gao 2017,2017,2 genes,Gao-2017-Characterization of two catalase-pero,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9633,PHI:7286,UniProt,W7NEP8,GenBank,EWG54767,,,7600,FvCP02,chromosome 11,,,,,PHI:7285,117187,Fusarium verticillioides,,A00999,stalk rot (maize); ear rot (maize); seedling blight (maize),monocots,4577,Zea mays (related: maize),cv. Silver Queen,,,shoot,catalase-peroxidase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28802018,PubMed,10.1111/mpp.12591,Mol Plant Pathol.2017 Aug 12,anthony.glenn@ars.usda.gov,Both ΔFvCP01 and ΔFvCP02 were more sensitive to H2O2 than the wild type in vitro and the ΔFvCP01/ΔFvCP02 double deletion were the most sensitive to H2O2.,S Gao 2017,2017,2 genes,Gao-2017-Characterization of two catalase-pero,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9634,PHI:7287,UniProt,Q87AV4,GenBank,AAO29547,,,Temecula1,MopB,,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana SR1,,,leaf,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28800709,PubMed,10.1094/MPMI-07-17-0161-R,Mol Plant Microbe Interact.2017 Aug 11,lzd0005@auburn.edu,"Deletion of the mopB gene impaired cell-to-cell aggregation, surface attachment, biofilm formation and completely abolished twitching motility.",H Chen 2017,2017,1 gene,Chen-2017-The major outer membrane protein Mop,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9635,PHI:7287,UniProt,Q87AV4,GenBank,AAO29547,,,Temecula1,MopB,,,,,,,2371,Xylella fastidiosa,183190,WM1-1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana SR1,,,leaf,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28800709,PubMed,10.1094/MPMI-07-17-0161-R,Mol Plant Microbe Interact.2017 Aug 11,lzd0005@auburn.edu,"Deletion of the mopB gene impaired cell-to-cell aggregation, surface attachment, biofilm formation and completely abolished twitching motility.",H Chen 2017,2017,1 gene,Chen-2017-The major outer membrane protein Mop,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9636,PHI:7288,UniProt,A0A0H2ZEE6,GenBank,ABJ12731,,,UCBPP-PA14,RhlI,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,LuxI/R quorum-sensing systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9637,PHI:7289,UniProt,A0A0H2ZEG8,GenBank,ABJ12732,,,UCBPP-PA14,RhlR,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,LuxI/R quorum-sensing systems,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9638,PHI:7290,UniProt,A0A0H2Z8S3,GenBank,ABJ10613,,,UCBPP-PA14,LasI,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,LuxI/R quorum-sensing systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9639,PHI:7291,UniProt,A0A0H2Z901,GenBank,ABJ10611,,,UCBPP-PA14,LasR,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,LuxI/R quorum-sensing systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9640,PHI:7292,UniProt,A0A0H2ZGH8,GenBank,ABJ13483,,,UCBPP-PA14,PhzA1,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9641,PHI:7293,UniProt,A0A0H2ZGA6,GenBank,ABJ13484,,,UCBPP-PA14,PhzB1,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9642,PHI:7294,UniProt,A0A0H2ZGB8,GenBank,ABJ13485,,,UCBPP-PA14,PhzC1,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9643,PHI:7295,UniProt,A0A0H2ZF69,GenBank,ABJ13486,,,UCBPP-PA14,PhzD1,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9644,PHI:7296,UniProt,A0A0H2ZG56,GenBank,ABJ13487,,,UCBPP-PA14,PhzE1,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9645,PHI:7297,UniProt,A0A0H2ZGI5,GenBank,ABJ13488,,,UCBPP-PA14,PhzF1,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9646,PHI:7298,UniProt,A0A0H2ZGB1,GenBank,ABJ13489,,,UCBPP-PA14,PhzG1,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9647,PHI:7299,UniProt,A0A0H2Z8X0,GenBank,ABJ11089,,,UCBPP-PA14,PhzA2,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9648,PHI:7300,UniProt,Q02L47,GenBank,ABJ11090,,,UCBPP-PA14,PhzB2,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9649,PHI:7301,UniProt,A0A0H2ZL76,GenBank,ABJ15680,,,UCBPP-PA14,PhzC2,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9650,PHI:7302,UniProt,A0A0H2ZKU3,GenBank,ABJ15681,,,UCBPP-PA14,PhzD2,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9651,PHI:7303,UniProt,A0A0H2Z9Z1,GenBank,ABJ11091,,,UCBPP-PA14,PhzE2,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9652,PHI:7304,UniProt,A0A0H2ZGI5,GenBank,ABJ11092,,,UCBPP-PA14,PhzF2,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9653,PHI:7305,UniProt,A0A0H2Z9T7,GenBank,ABJ11093,,,UCBPP-PA14,PhzG2,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9654,PHI:7292,UniProt,A0A0H2ZGH8,GenBank,ABJ13483,,,UCBPP-PA14,PhzA1,,,,,,PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9655,PHI:7293,UniProt,A0A0H2ZGA6,GenBank,ABJ13484,,,UCBPP-PA14,PhzB1,,,,,,PHI:7292; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9656,PHI:7294,UniProt,A0A0H2ZGB8,GenBank,ABJ13485,,,UCBPP-PA14,PhzC1,,,,,,PHI:7292; PHI:7293; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9657,PHI:7295,UniProt,A0A0H2ZF69,GenBank,ABJ13486,,,UCBPP-PA14,PhzD1,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9658,PHI:7296,UniProt,A0A0H2ZG56,GenBank,ABJ13487,,,UCBPP-PA14,PhzE1,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9659,PHI:7297,UniProt,A0A0H2ZGI5,GenBank,ABJ13488,,,UCBPP-PA14,PhzF1,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9660,PHI:7298,UniProt,A0A0H2ZGB1,GenBank,ABJ13489,,,UCBPP-PA14,PhzG1,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9661,PHI:7299,UniProt,A0A0H2Z8X0,GenBank,ABJ11089,,,UCBPP-PA14,PhzA2,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9662,PHI:7300,UniProt,Q02L47,GenBank,ABJ11090,,,UCBPP-PA14,PhzB2,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9663,PHI:7301,UniProt,A0A0H2ZL76,GenBank,ABJ15680,,,UCBPP-PA14,PhzC2,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7302; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9664,PHI:7302,UniProt,A0A0H2ZKU3,GenBank,ABJ15681,,,UCBPP-PA14,PhzD2,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7303; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9665,PHI:7303,UniProt,A0A0H2Z9Z1,GenBank,ABJ11091,,,UCBPP-PA14,PhzE2,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7304; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9666,PHI:7304,UniProt,A0A0H2ZGI5,GenBank,ABJ11092,,,UCBPP-PA14,PhzF2,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7305; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9667,PHI:7305,UniProt,A0A0H2Z9T7,GenBank,ABJ11093,,,UCBPP-PA14,PhzG2,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7288,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,phenazine biosynthesis genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9668,PHI:7288,UniProt,A0A0H2ZEE6,GenBank,ABJ12731,,,UCBPP-PA14,RhlI,,,,,,PHI:7292; PHI:7293; PHI:7294; PHI:7295; PHI:7296; PHI:7297; PHI:7298; PHI:7299; PHI:7300; PHI:7301; PHI:7302; PHI:7303; PHI:7304; PHI:7305,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,LuxI/R quorum-sensing systems,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9669,PHI:7288,UniProt,A0A0H2ZEE6,GenBank,ABJ12731,,,UCBPP-PA14,RhlI,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,LuxI/R quorum-sensing systems,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9670,PHI:7289,UniProt,A0A0H2ZEG8,GenBank,ABJ12732,,,UCBPP-PA14,RhlR,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,LuxI/R quorum-sensing systems,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9671,PHI:7290,UniProt,A0A0H2Z8S3,GenBank,ABJ10613,,,UCBPP-PA14,LasI,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,LuxI/R quorum-sensing systems,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9672,PHI:7291,UniProt,A0A0H2Z901,GenBank,ABJ10611,,,UCBPP-PA14,LasR,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,LuxI/R quorum-sensing systems,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28715477,PubMed,10.1371/journal.ppat.1006504,PLoS Pathog.2017 Jul 17;13(7):e1006504,bbassler@princeton.edu,"In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.",S Mukherjee 2017,2017,18 genes,Mukherjee-2017-The RhlR quorum-sensing recepto,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9673,PHI:7306,UniProt,C4WYV4,,,,,,KP1_4563,,,,,,,573,Klebsiella pneumoniae,484021,NTUH-K2044,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28732013,PubMed,10.1371/journal.pone.0180666,PLoS One.2017 Jul 21;12(7):e0180666,liylyl@126.com,CRP negatively regulates KP1_4563 by directly binding to the promoter region of KP1_4563 and that KP1_4563 negatively regulates the function of type 3 fimbriae in an unknown manner.,M Luo 2017,2017,1 gene,Luo-2017-The KP1_4563 gene is regulated by the,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9674,PHI:7307,UniProt,A0A0H3N916,GenBank,CBW16569,,,SL1344,AcrB,,D408A,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,efflux pump membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,28720734,PubMed,10.1128/mBio.00968-17,MBio.2017 Jul 18;8(4). pii: e00968-17,l.j.v.piddock@bham.ac.uk,The loss of efflux function of AcrB causes loss of virulence in S. Typhimurium.,X Wang-Kan 2017,2017,1 gene,Zhang-2017-Expression of HopAI interferes with,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9675,PHI:7307,UniProt,A0A0H3N916,GenBank,CBW16569,,,SL1344,AcrB,,D408A,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,efflux pump membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,28720734,PubMed,10.1128/mBio.00968-17,MBio.2017 Jul 18;8(4). pii: e00968-17,l.j.v.piddock@bham.ac.uk,The loss of efflux function of AcrB causes loss of virulence in S. Typhimurium.,X Wang-Kan 2017,2017,1 gene,Zhang-2017-Expression of HopAI interferes with,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9676,PHI:7307,UniProt,A0A0H3N916,GenBank,CBW16569,,,SL1344,AcrB,,D408A,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,intestinal epithelium,efflux pump membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,28720734,PubMed,10.1128/mBio.00968-17,MBio.2017 Jul 18;8(4). pii: e00968-17,l.j.v.piddock@bham.ac.uk,The loss of efflux function of AcrB causes loss of virulence in S. Typhimurium. embryonic intestinal epithelial cells,X Wang-Kan 2017,2017,1 gene,Zhang-2017-Expression of HopAI interferes with,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9677,PHI:7307,UniProt,A0A0H3N916,GenBank,CBW16569,,,SL1344,AcrB,,D408A,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelium,efflux pump membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,28720734,PubMed,10.1128/mBio.00968-17,MBio.2017 Jul 18;8(4). pii: e00968-17,l.j.v.piddock@bham.ac.uk,The loss of efflux function of AcrB causes loss of virulence in S. Typhimurium.,X Wang-Kan 2017,2017,1 gene,Zhang-2017-Expression of HopAI interferes with,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9678,PHI:7307,UniProt,A0A0H3N916,GenBank,CBW16569,,,SL1344,AcrB,,D408A,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,efflux pump membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,28720734,PubMed,10.1128/mBio.00968-17,MBio.2017 Jul 18;8(4). pii: e00968-17,l.j.v.piddock@bham.ac.uk,The loss of efflux function of AcrB causes loss of virulence in S. Typhimurium.,X Wang-Kan 2017,2017,1 gene,Zhang-2017-Expression of HopAI interferes with,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9679,PHI:7307,UniProt,A0A0H3N916,GenBank,CBW16569,,,SL1344,AcrB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,intestinal epithelium,efflux pump membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28720734,PubMed,10.1128/mBio.00968-17,MBio.2017 Jul 18;8(4). pii: e00968-17,l.j.v.piddock@bham.ac.uk,The loss of efflux function of AcrB causes loss of virulence in S. Typhimurium.,X Wang-Kan 2017,2017,1 gene,Zhang-2017-Expression of HopAI interferes with,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9680,PHI:7307,UniProt,A0A0H3N916,GenBank,CBW16569,,,SL1344,AcrB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelium,efflux pump membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28720734,PubMed,10.1128/mBio.00968-17,MBio.2017 Jul 18;8(4). pii: e00968-17,l.j.v.piddock@bham.ac.uk,The loss of efflux function of AcrB causes loss of virulence in S. Typhimurium.,X Wang-Kan 2017,2017,1 gene,Zhang-2017-Expression of HopAI interferes with,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9681,PHI:7307,UniProt,A0A0H3N916,GenBank,CBW16569,,,SL1344,AcrB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,efflux pump membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28720734,PubMed,10.1128/mBio.00968-17,MBio.2017 Jul 18;8(4). pii: e00968-17,l.j.v.piddock@bham.ac.uk,The loss of efflux function of AcrB causes loss of virulence in S. Typhimurium.,X Wang-Kan 2017,2017,1 gene,Zhang-2017-Expression of HopAI interferes with,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9682,PHI:7308,,no data found,GenBank,SPA0084,,,,ReaL,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,virulence related small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28799693,PubMed,10.1111/1462-2920.13886,Environ Microbiol.2017 Aug 11,silvia.ferrara@unimi.it,"Perturbations of ReaL levels affect pyocyanin synthesis, biofilm formation and swarming motility, processes that are known to be influenced by Pseudomonas quinolone signal (PQS) synthesis.",S Carloni 2017,2017,1 gene,Carloni-2017-The small RNA ReaL_ a novel regul,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9683,PHI:7308,,no data found,GenBank,SPA0084,,,,ReaL,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,virulence related small RNA,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28799693,PubMed,10.1111/1462-2920.13886,Environ Microbiol.2017 Aug 11,silvia.ferrara@unimi.it,"Perturbations of ReaL levels affect pyocyanin synthesis, biofilm formation and swarming motility, processes that are known to be influenced by Pseudomonas quinolone signal (PQS) synthesis.",S Carloni 2017,2017,1 gene,Carloni-2017-The small RNA ReaL_ a novel regul,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9684,PHI:7309,UniProt,Q63K35,GenBank,CAH39004,,,K96243,BipC,chromosome 2,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,type III effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,28770177,PubMed,10.3389/fcimb.2017.00333,Front Cell Infect Microbiol.2017 Jul 19;7:333,jo.stevens@roslin.ed.ac.uk,"It was shown that BipC directly interacted with actin, preferentially with actin polymers (F-actin) and had the ability to polymerize actin but did not stabilize F-actin filaments, indicating a functionally distinct interaction with actin.",C W Vander Broek 2017,2017,1 gene,"Vander Broek-2017-BipC, a Predicted Burkholder",BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9685,PHI:7310,UniProt,Q87EB0,GenBank,AAO28287,,,Temecula1,RpfF,,,,,,,2371,Xylella fastidiosa,160492,9a5c,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. RP-1,,,leaf,enzyme having thioesterase and dehydratase activities,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,28777044,PubMed,10.1094/MPMI-07-17-0167-R,Mol Plant Microbe Interact.2017 Aug 4,alessandra@centrodecitricultura.br,Ectopic expression of rpfF in both transgenic tobacco and sweet orange also confers a reduction in disease severity incited by X. fastidiosa and reduces its colonization of those plants.,R Caserta 2017,2017,1 gene,Caserta-2017-Ectopic expression of Xylella fas,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9686,PHI:7310,UniProt,Q87EB0,GenBank,AAO28287,,,Temecula1,RpfF,,,,,,,2371,Xylella fastidiosa,160492,9a5c,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Hamlin,,,leaf,enzyme having thioesterase and dehydratase activities,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,28777044,PubMed,10.1094/MPMI-07-17-0167-R,Mol Plant Microbe Interact.2017 Aug 4,alessandra@centrodecitricultura.br,Ectopic expression of rpfF in both transgenic tobacco and sweet orange also confers a reduction in disease severity incited by X. fastidiosa and reduces its colonization of those plants.,R Caserta 2017,2017,1 gene,Caserta-2017-Ectopic expression of Xylella fas,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9687,PHI:7310,UniProt,Q87EB0,GenBank,AAO28287,,,Temecula1,RpfF,,,,,,,2371,Xylella fastidiosa,160492,9a5c,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pineapple,,,leaf,enzyme having thioesterase and dehydratase activities,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,28777044,PubMed,10.1094/MPMI-07-17-0167-R,Mol Plant Microbe Interact.2017 Aug 4,alessandra@centrodecitricultura.br,Ectopic expression of rpfF in both transgenic tobacco and sweet orange also confers a reduction in disease severity incited by X. fastidiosa and reduces its colonization of those plants.,R Caserta 2017,2017,1 gene,Caserta-2017-Ectopic expression of Xylella fas,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9688,PHI:7311,UniProt,Q5A683,GenBank,AOW29217,,,SC5314,Bas1,chromosome 4,,,,,,5476,Candida albicans,,DAY185,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,transcription factor,,,AMP biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,28776040,PubMed,10.1128/mSphere.00161-17,mSphere.2017 Aug 2;2(4). pii: e00161-17,rolfesr@georgetown.edu,Grf10 coordinated metabolic effects on nucleotide metabolism by interaction with Bas1 and indicated that AMP biosynthesis and its regulation are important for C. albicans growth and virulence.,T Wangsanut 2017,2017,1 gene,Wangsanut-2017-Grf10 and Bas1 Regulate Transcr,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9689,PHI:7312,UniProt,P15926,GenBank,AAA26960,,,,ScpA,,,,,,,1314,Streptococcus pyogenes,301447,serotype M1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,deep inguinal lymph node; spleen; liver; blood,C5a peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,28806402,PubMed,10.1371/journal.ppat.1006493,PLoS Pathog.2017 Aug 14;13(8):e1006493,nicola.lynskey07@imperial.ac.uk,"Host gene alteration data available for C3 and C5. Despite clear effects on human complement, expression of ScpA reduced clearance of group A streptococci in vivo in wildtype and C5 deficient mice, and promoted systemic bacterial dissemination in mice that lacked both C3 and C5, suggesting an additional complement-independent role for ScpA in streptococcal pathogenesis.",N N Lynskey 2017,2017,1 gene,Lynskey-2017-Multi-functional mechanisms of im,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9690,PHI:7312,UniProt,P15926,GenBank,AAA26960,,,,ScpA,,,,,,,1314,Streptococcus pyogenes,410076,serotype M89,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,deep inguinal lymph node; spleen; liver; blood,C5a peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,28806402,PubMed,10.1371/journal.ppat.1006493,PLoS Pathog.2017 Aug 14;13(8):e1006493,nicola.lynskey07@imperial.ac.uk,"Host gene alteration data available for C3 and C5. Despite clear effects on human complement, expression of ScpA reduced clearance of group A streptococci in vivo in wildtype and C5 deficient mice, and promoted systemic bacterial dissemination in mice that lacked both C3 and C5, suggesting an additional complement-independent role for ScpA in streptococcal pathogenesis.",N N Lynskey 2017,2017,1 gene,Lynskey-2017-Multi-functional mechanisms of im,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9691,PHI:7312,UniProt,P15926,GenBank,AAA26960,,,,ScpA,,H193A,,,,,1314,Streptococcus pyogenes,410076,serotype M89,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,deep inguinal lymph node; spleen; liver; blood,C5a peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,28806402,PubMed,10.1371/journal.ppat.1006493,PLoS Pathog.2017 Aug 14;13(8):e1006493,nicola.lynskey07@imperial.ac.uk,"Host gene alteration data available for C3 and C5. Despite clear effects on human complement, expression of ScpA reduced clearance of group A streptococci in vivo in wildtype and C5 deficient mice, and promoted systemic bacterial dissemination in mice that lacked both C3 and C5, suggesting an additional complement-independent role for ScpA in streptococcal pathogenesis.",N N Lynskey 2017,2017,1 gene,Lynskey-2017-Multi-functional mechanisms of im,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9692,PHI:7313,,no data found,,,,,,PcCRN83_152,,,,,,,4784,Phytophthora capsici,763924,LT1534,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28779542,PubMed,10.1111/mpp.12590,Mol Plant Pathol.2017 Aug 5,e.huitema@dundee.ac.uk,PcCRN83_152 induced cell death is not a requisite for virulence function.,T M M M Amaro 2017,2017,1 gene,Amaro-2017-Random mutagenesis screen shows tha,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9693,PHI:7314,UniProt,A0A0J9WWZ0,GenBank,ACD59164,,,PXO99A,fliTX,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. indica cv. IR24,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28793882,PubMed,10.1186/s12866-017-1083-6,BMC Microbiol. 2017 Aug 9;17(1):171,hechenyang@caas.cn,"The expression of two T3SS regulator genes, hrpG and hrpX, were attenuated in the ΔfliTX mutant and decreased hrp gene expression in the ΔfliTX mutant. FliTX is required for flagellar motility.",C Yu 2017,2017,1 gene,Yu-2017-RpoN2- and FliA-regulated fliTX is ind,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9694,PHI:7315,UniProt,Q9I0K5,GenBank,AE004691_12,,,PAO1,srbA,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,sRNA regulator of biofilm,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28771593,PubMed,10.1371/journal.pone.0182582,PLoS One. 2017 Aug 3;12(8):e0182582,tmah@uottawa.ca,"The deleted mutant strain produced only 34% the amount of biofilm (p < 0.05) compared to the wild-type strain, in contrast to its deficiency in biofilm formation, ΔsrbA demonstrated no significant reduction in its ability to adhere to surfaces.",P K Taylor 2017,2017,1 gene,Taylor-2017-A novel small RNA is important for,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9695,PHI:7316,UniProt,B8NKR0,GenBank,EED49233,,,NRRL3357,dot1,,,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::AfpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,histone methyltransferase activity,,,,reduced virulence,,,,,,reduced,,reduced,,no,methylmercuric sulphate; hydroxyurea; sodium dodecyl sulfate (SDS); tert-butyl hydroperoxide,methylmercuric sulphate: CAS:3810-81-9; hydroxyurea: CHEBI:44423; sodium dodecyl sulfate (SDS): CHEBI:8984; tert-butyl hydroperoxide: CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,28737735,PubMed,10.3390/toxins9070232,Toxins (Basel). 2017 Jul 24;9(7). pii: E232,lllyiyuan@sina.com,"Aflatoxin, AFB1 and AFB2 production was severely impaired in the Δdot1 mutant, deltadot1 mutant showed less sensitivity to genotoxicity stress, cell wall-damaging agents and oxidative stress and",L Liang 2017,2017,1 gene,Liang-2017-The Putative Histone Methyltransfer,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9696,PHI:7317,UniProt,G4MY65,GenBank,EHA54396,,,70-15,Tpc1,chromosome 2,,,Mst12,UniProt: G4N3L5; GenBank: EHA52690,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,transcription factor for polarity control 1,,,MAPK-Pmk1 signalling pathway,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced; aberrant,reduced,no,calcofluor white (CFW); Congo red (CR); NaCl,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,28742127,PubMed,10.1371/journal.ppat.1006516,PLoS Pathog. 2017 Jul 24;13(7):e1006516,ane.sesma@upm.es,Transcription factor Tpc1 regulated appressorium maturation and plant infection.,R Galhano 2017,2017,6 genes,Galhano-2017-Tpc1 is an important Zn(II)2Cys6,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9697,PHI:7317,UniProt,G4MY65,GenBank,EHA54396,,,70-15,Tpc1,chromosome 2,,,Mst12,UniProt: G4N3L5; GenBank: EHA52690,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,transcription factor for polarity control 1,,,MAPK-Pmk1 signalling pathway,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced; aberrant,reduced,no,calcofluor white (CFW); Congo red (CR); NaCl,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,28742127,PubMed,10.1371/journal.ppat.1006516,PLoS Pathog. 2017 Jul 24;13(7):e1006516,ane.sesma@upm.es,Transcription factor Tpc1 regulated appressorium maturation and plant infection.,R Galhano 2017,2017,6 genes,Galhano-2017-Tpc1 is an important Zn(II)2Cys6,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9698,PHI:7318,UniProt,G4MRN1,GenBank,EHA57454,,,70-15,noxD,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,root; leaf,PRO41 protein,,,MAPK-Pmk1 signalling pathway,loss of pathogenicity,yes,,yes,,,,,increased,,no,calcofluor white (CFW); Congo red (CR); NaCl; LiCl; methyl viologen; H2O2; diphenylene iodonium,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; methyl viologen: CHEBI:28786; H2O2: CHEBI:16240; diphenyleneiodonium: CHEBI:77986,,,,,gene deletion: full,,,YVS,28742127,PubMed,10.1371/journal.ppat.1006516,PLoS Pathog. 2017 Jul 24;13(7):e1006516,ane.sesma@upm.es,Transcription factor Tpc1 regulated appressorium maturation and plant infection.,R Galhano 2017,2017,6 genes,Galhano-2017-Tpc1 is an important Zn(II)2Cys6,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9699,PHI:7319,UniProt,G4MQ14,GenBank,EHA56407,,,70-15,CON6,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28742127,PubMed,10.1371/journal.ppat.1006516,PLoS Pathog. 2017 Jul 24;13(7):e1006516,ane.sesma@upm.es,Transcription factor Tpc1 regulated appressorium maturation and plant infection.,R Galhano 2017,2017,6 genes,Galhano-2017-Tpc1 is an important Zn(II)2Cys6,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9700,PHI:7320,UniProt,G4MQW5,GenBank,EHA58196,,,70-15,GH18,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,glycosidase hydrolase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28742127,PubMed,10.1371/journal.ppat.1006516,PLoS Pathog. 2017 Jul 24;13(7):e1006516,ane.sesma@upm.es,Transcription factor Tpc1 regulated appressorium maturation and plant infection.,R Galhano 2017,2017,6 genes,Galhano-2017-Tpc1 is an important Zn(II)2Cys6,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9701,PHI:7321,UniProt,G4MM19,GenBank,EHA56904,,,70-15,PEBP1,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28742127,PubMed,10.1371/journal.ppat.1006516,PLoS Pathog. 2017 Jul 24;13(7):e1006516,ane.sesma@upm.es,Transcription factor Tpc1 regulated appressorium maturation and plant infection.,R Galhano 2017,2017,6 genes,Galhano-2017-Tpc1 is an important Zn(II)2Cys6,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9702,PHI:7322,UniProt,G5EI13,GenBank,EAQ70647,,,70-15,PEBP2,chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28742127,PubMed,10.1371/journal.ppat.1006516,PLoS Pathog. 2017 Jul 24;13(7):e1006516,ane.sesma@upm.es,Transcription factor Tpc1 regulated appressorium maturation and plant infection.,R Galhano 2017,2017,6 genes,Galhano-2017-Tpc1 is an important Zn(II)2Cys6,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9703,PHI:7321,UniProt,G4MM19,GenBank,EHA56904,,,70-15,PEBP1,chromosome 1,,,,,PHI:7322,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28742127,PubMed,10.1371/journal.ppat.1006516,PLoS Pathog. 2017 Jul 24;13(7):e1006516,ane.sesma@upm.es,Transcription factor Tpc1 regulated appressorium maturation and plant infection.,R Galhano 2017,2017,6 genes,Galhano-2017-Tpc1 is an important Zn(II)2Cys6,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9704,PHI:7322,UniProt,G5EI13,GenBank,EAQ70647,,,70-15,PEBP2,chromosome 7,,,,,PHI:7321,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28742127,PubMed,10.1371/journal.ppat.1006516,PLoS Pathog. 2017 Jul 24;13(7):e1006516,ane.sesma@upm.es,Transcription factor Tpc1 regulated appressorium maturation and plant infection.,R Galhano 2017,2017,6 genes,Galhano-2017-Tpc1 is an important Zn(II)2Cys6,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9705,PHI:7323,UniProt,Q8XQ67,GenBank,AEC03968,,,GMI1000,ralA,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Craigella,,,root; stem,ralfuranone synthase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28722830,PubMed,10.1111/mpp.12583,Mol Plant Pathol. 2017 Jul 19,yhikichi@kochi-u.ac.jp,The findings indicated that ralfuranones were implicated in not only development of mBFs by strain OE1-1 but also suppression of the QS-mediated negative regulation of mBF formation.,Y Mori 2017,2017,1 gene,Mori-2017-Ralfuranones contribute to mushroom-,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9706,PHI:7324,UniProt,W8SAS9,GenBank,AHM10189,,,,PsCaMKL1,,,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,calmodulin-dependent protein kinase,,,signaling pathway,reduced virulence,,,,,,,,,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,altered gene expression / gene regulation: silencing,,,YVS,28805296,PubMed,10.1111/1462-2920.13881,Environ Microbiol. 2017 Aug 14,guojunwgq@nwafu.edu.cn,Knock down of PsCaMKL1 using host-induced gene silencing (HIGS) reduced the virulence of Pst accompanied by reactive oxygen species (ROS) accumulation and a hypersensitive response.,M Jiao 2017,2017,1 gene,Jiao-2017-Basidiomycete-specific PsCaMKL1 enco,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9707,PHI:7325,,no data found,,,,,,PpzA,,,,SdsA,UniProt: B0XNQ8; GenBank: EDP55818,,746128,Aspergillus fumigatus,1266464,CEA17,invasive aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,catalytic subunit of protein phosphatase Z,,,MpkA pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28753224,PubMed,10.1111/cmi.12770,Cell Microbiol. 2017 Jul 28,ggoldman@usp.br,"PpzA is important for the fungal virulence through multiple mechanisms, such as low tolerance to oxidative stress and iron starvation and the regulation of SM production.",A O Manfiolli 2017,2017,1 gene,Manfiolli-2017-Aspergillus fumigatus protein p,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9708,PHI:7326,UniProt,E9B208,GenBank,CBZ29265,,,MHOM/GT/2001/U1103,ALD1,chromosome 30,,,,,,5665,Leishmania mexicana,,MNYC/BZ/62/M379,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bone marrow-derived macrophage,cytosolic protein that contains a cryptic ATP/GTP binding P-loop,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28742133,PubMed,10.1371/journal.pntd.0005782,PLoS Negl Trop Dis. 2017 Jul 24;11(7):e0005782,vyacheslav.yurchenko@osu.cz,"Results suggested that ALD1 functions in L. mexicana's general metabolic network, rather than function in specific aspect of virulence.",A Ishemgulova 2017,2017,1 gene,Ishemgulova-2017-A putative ATP_GTP binding pr,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9709,PHI:7326,UniProt,E9B208,GenBank,CBZ29265,,,MHOM/GT/2001/U1103,ALD1,chromosome 30,,,,,,5665,Leishmania mexicana,,MNYC/BZ/62/M379,leishmaniasis,flies,7200,Lutzomyia longipalpis (no common name found),,,,gut,cytosolic protein that contains a cryptic ATP/GTP binding P-loop,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28742133,PubMed,10.1371/journal.pntd.0005782,PLoS Negl Trop Dis. 2017 Jul 24;11(7):e0005782,vyacheslav.yurchenko@osu.cz,"Results suggested that ALD1 functions in L. mexicana's general metabolic network, rather than function in specific aspect of virulence.",A Ishemgulova 2017,2017,1 gene,Ishemgulova-2017-A putative ATP_GTP binding pr,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9710,PHI:7326,UniProt,E9B208,GenBank,CBZ29265,,,MHOM/GT/2001/U1103,ALD1,chromosome 30,,,,,,5665,Leishmania mexicana,,MNYC/BZ/62/M379,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ear,cytosolic protein that contains a cryptic ATP/GTP binding P-loop,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28742133,PubMed,10.1371/journal.pntd.0005782,PLoS Negl Trop Dis. 2017 Jul 24;11(7):e0005782,vyacheslav.yurchenko@osu.cz,"Results suggested that ALD1 functions in L. mexicana's general metabolic network, rather than function in specific aspect of virulence.",A Ishemgulova 2017,2017,1 gene,Ishemgulova-2017-A putative ATP_GTP binding pr,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9711,PHI:7327,UniProt,D0ERY7,GenBank,ACX31736,,,B157,MopdeH,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cyclic AMP phosphodiesterase,,,cyclic AMP signaling pathway,reduced virulence,,,,,,reduced; aberrant,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28752677,PubMed,10.1111/mpp.12586,Mol Plant Pathol. 2017 Jul 27,hfzhang@njau.edu.cn,"All domain mutation and chimera transformants showed defects in Mps1 phosphorylation, chimera transformants showed high intracellular cAMP levels, this is due to the defects in phosphodiesterase activity.",L N Yang 2017,2017,2 genes,Yang-2017-New findings on phosphodiesterases,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9712,PHI:7327,UniProt,D0ERY7,GenBank,ACX31736,,,B157,MopdeH,,MoPdeHEAL(AAA) or MoPdeHdeltaHD,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cyclic AMP phosphodiesterase,,,cyclic AMP signaling pathway,reduced virulence,,,,,,reduced; aberrant,,,,no,,,,,,,gene mutation,,,YVS,28752677,PubMed,10.1111/mpp.12586,Mol Plant Pathol. 2017 Jul 27,hfzhang@njau.edu.cn,"All domain mutation and chimera transformants showed defects in Mps1 phosphorylation, chimera transformants showed high intracellular cAMP levels, this is due to the defects in phosphodiesterase activity.",L N Yang 2017,2017,2 genes,Yang-2017-New findings on phosphodiesterases,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9713,PHI:7327,UniProt,D0ERY7,GenBank,ACX31736,,,B157,MopdeH,,MoPdeHdeltaHD+L1L2 or MoPdeHdeltaHD+L1 or MoPdeHdeltaHD+L2,,,,PHI:7328,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cyclic AMP phosphodiesterase,,,cyclic AMP signaling pathway,reduced virulence,,,,,,reduced; aberrant,,,,no,,,,,,,gene mutation,,,YVS,28752677,PubMed,10.1111/mpp.12586,Mol Plant Pathol. 2017 Jul 27,hfzhang@njau.edu.cn,"All domain mutation and chimera transformants showed defects in Mps1 phosphorylation, chimera transformants showed high intracellular cAMP levels, this is due to the defects in phosphodiesterase activity.",L N Yang 2017,2017,2 genes,Yang-2017-New findings on phosphodiesterases,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9714,PHI:7328,UniProt,D0ERY8,GenBank,ACX31737,,,B157,MopdeL,,MoPdeHdeltaHD+L1L2 or MoPdeHdeltaHD+L1 or MoPdeHdeltaHD+L2,,,,PHI:7327,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cyclic AMP phosphodiesterase,,,cyclic AMP signaling pathway,reduced virulence,,,,,,reduced; aberrant,,,,no,,,,,,,gene mutation,,,YVS,28752677,PubMed,10.1111/mpp.12586,Mol Plant Pathol. 2017 Jul 27,hfzhang@njau.edu.cn,"All domain mutation and chimera transformants showed defects in Mps1 phosphorylation, chimera transformants showed high intracellular cAMP levels, this is due to the defects in phosphodiesterase activity.",L N Yang 2017,2017,2 genes,Yang-2017-New findings on phosphodiesterases,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9715,PHI:7328,UniProt,D0ERY8,GenBank,ACX31737,,,B157,MopdeL,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cyclic AMP phosphodiesterase,,,cyclic AMP signaling pathway,reduced virulence,,,,,,reduced; aberrant,,,,no,,,,,,,gene mutation,,,YVS,28752677,PubMed,10.1111/mpp.12586,Mol Plant Pathol. 2017 Jul 27,hfzhang@njau.edu.cn,"All domain mutation and chimera transformants showed defects in Mps1 phosphorylation, chimera transformants showed high intracellular cAMP levels, this is due to the defects in phosphodiesterase activity.",L N Yang 2017,2017,2 genes,Yang-2017-New findings on phosphodiesterases,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9716,PHI:7329,UniProt,G2WYZ0,GenBank,EGY21792,,,VdLs.17,STT3,,,,,,,27337,Verticillium dahliae,,Vd991,Verticillium wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,root; stem; leaf,catalytic subunit of the multi-subunit oligosaccharyl transferase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28798981,PubMed,10.1007/s00294-017-0729-0,Curr Genet. 2017 Aug 10,chenghongmei@caas.cn,"The full virulence of V. dahliae was mediated by STT3 through its impact on various aspects of mycelial growth, conidia production, carbon degradation and glycoprotein secretion. Transgenic tobacco with dsSTT3 elevated the resistance against V. dahliae",X Su 2017,2017,1 gene,Su-2017-The oligosaccharyl transferase subunit,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9717,PHI:7329,UniProt,G2WYZ0,GenBank,EGY21792,,,VdLs.17,STT3,,,,,,,27337,Verticillium dahliae,,Vd991,Verticillium wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,root; stem; leaf,catalytic subunit of the multi-subunit oligosaccharyl transferase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,other evidence: transgenic plants,,,YVS,28798981,PubMed,10.1007/s00294-017-0729-0,Curr Genet. 2017 Aug 10,chenghongmei@caas.cn,"The full virulence of V. dahliae was mediated by STT3 through its impact on various aspects of mycelial growth, conidia production, carbon degradation and glycoprotein secretion. Transgenic tobacco with dsSTT3 elevated the resistance against V. dahliae",X Su 2017,2017,1 gene,Su-2017-The oligosaccharyl transferase subunit,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9718,PHI:7330,UniProt,G2X7U7,GenBank,EGY15065,,,VdLs.17,Vph1,,,,,,,27337,Verticillium dahliae,,Dvd-T5,Verticillium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,root; leaf,transcription factor steA,,,,loss of pathogenicity,,,no,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28727279,PubMed,10.1111/mpp.12584,Mol Plant Pathol. 2017 Jul 20,mariola@eelm.csic.es,Deletion of vph1 impairs penetration of the root cortex whereas deletion of vhb1 affects proliferation in the xylem.,J L Sarmiento-Villamil 2017,2017,2 genes,Sarmiento-Villa-2017-Characterization of Two H,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9719,PHI:7331,UniProt,G2XF54,GenBank,EGY18452,,,VdLs.17,Vhb1,,,,,,,27337,Verticillium dahliae,,Dvd-T5,Verticillium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,root; leaf,homeobox protein 1,,,,loss of pathogenicity,,,no,,,aberrant,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28727279,PubMed,10.1111/mpp.12584,Mol Plant Pathol. 2017 Jul 20,mariola@eelm.csic.es,Deletion of vph1 impairs penetration of the root cortex whereas deletion of vhb1 affects proliferation in the xylem.,J L Sarmiento-Villamil 2017,2017,2 genes,Sarmiento-Villa-2017-Characterization of Two H,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9720,PHI:7330,UniProt,G2X7U7,GenBank,EGY15065,,,VdLs.17,Vph1,,,,,,,27337,Verticillium dahliae,,Dvd-T5,Verticillium wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,root; leaf,transcription factor steA,,,,loss of pathogenicity,,,no,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28727279,PubMed,10.1111/mpp.12584,Mol Plant Pathol. 2017 Jul 20,mariola@eelm.csic.es,Deletion of vph1 impairs penetration of the root cortex whereas deletion of vhb1 affects proliferation in the xylem.,J L Sarmiento-Villamil 2017,2017,2 genes,Sarmiento-Villa-2017-Characterization of Two H,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9721,PHI:7331,UniProt,G2XF54,GenBank,EGY18452,,,VdLs.17,Vhb1,,,,,,,27337,Verticillium dahliae,,Dvd-T5,Verticillium wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,root; leaf,homeobox protein 1,,,,loss of pathogenicity,,,no,,,aberrant,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28727279,PubMed,10.1111/mpp.12584,Mol Plant Pathol. 2017 Jul 20,mariola@eelm.csic.es,Deletion of vph1 impairs penetration of the root cortex whereas deletion of vhb1 affects proliferation in the xylem.,J L Sarmiento-Villamil 2017,2017,2 genes,Sarmiento-Villa-2017-Characterization of Two H,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9722,PHI:7330,UniProt,G2X7U7,GenBank,EGY15065,,,VdLs.17,Vph1,,,,,,,27337,Verticillium dahliae,,Dvd-T5,Verticillium wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,,transcription factor steA,,,,loss of pathogenicity,,,no,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28727279,PubMed,10.1111/mpp.12584,Mol Plant Pathol. 2017 Jul 20,mariola@eelm.csic.es,Deletion of vph1 impairs penetration of the root cortex whereas deletion of vhb1 affects proliferation in the xylem.,J L Sarmiento-Villamil 2017,2017,2 genes,Sarmiento-Villa-2017-Characterization of Two H,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9723,PHI:7331,UniProt,G2XF54,GenBank,EGY18452,,,VdLs.17,Vhb1,,,,,,,27337,Verticillium dahliae,,Dvd-T5,Verticillium wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,,homeobox protein 1,,,,loss of pathogenicity,,,no,,,aberrant,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28727279,PubMed,10.1111/mpp.12584,Mol Plant Pathol. 2017 Jul 20,mariola@eelm.csic.es,Deletion of vph1 impairs penetration of the root cortex whereas deletion of vhb1 affects proliferation in the xylem.,J L Sarmiento-Villamil 2017,2017,2 genes,Sarmiento-Villa-2017-Characterization of Two H,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9724,PHI:7332,UniProt,B0XWE4,GenBank,EDP54396,,,A1163,pptA,,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,phosphopantetheinyl transferase,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28720735,PubMed,10.1128/mBio.01504-16,MBio. 2017 Jul 18;8(4). pii: e01504-16,axel.brakhage@leibniz-hki.de,"PptA is required to synthesize the immunotoxic compound gliotoxin, DHN-melanin, immunotoxic secondary metabolites are absent in pptA null mutant. The pptA null mutant stimulated dendritic cells to produce immunomodulatory cytokines and enhances phagolysosome acidification.",A Johns 2017,2017,4 genes,Johns-2017-A Nonredundant Phosphopantetheinyl,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9725,PHI:7333,UniProt,B0XW64,GenBank,EDP54316,,,A1163,sidA,,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,produce siderophore,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28720735,PubMed,10.1128/mBio.01504-16,MBio. 2017 Jul 18;8(4). pii: e01504-16,axel.brakhage@leibniz-hki.de,"PptA is required to synthesize the immunotoxic compound gliotoxin, DHN-melanin, immunotoxic secondary metabolites are absent in pptA null mutant. The pptA null mutant stimulated dendritic cells to produce immunomodulatory cytokines and enhances phagolysosome acidification.",A Johns 2017,2017,4 genes,Johns-2017-A Nonredundant Phosphopantetheinyl,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9726,PHI:7332,UniProt,B0XWE4,GenBank,EDP54396,,,A1163,pptA,,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,phosphopantetheinyl transferase,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28720735,PubMed,10.1128/mBio.01504-16,MBio. 2017 Jul 18;8(4). pii: e01504-16,axel.brakhage@leibniz-hki.de,"PptA is required to synthesize the immunotoxic compound gliotoxin, DHN-melanin, immunotoxic secondary metabolites are absent in pptA null mutant. The pptA null mutant stimulated dendritic cells to produce immunomodulatory cytokines and enhances phagolysosome acidification.",A Johns 2017,2017,4 genes,Johns-2017-A Nonredundant Phosphopantetheinyl,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9727,PHI:7334,UniProt,B0Y6V5,GenBank,EDP50490,,,A1163,aarA,,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,alpha-aminoadipate reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28720735,PubMed,10.1128/mBio.01504-16,MBio. 2017 Jul 18;8(4). pii: e01504-16,axel.brakhage@leibniz-hki.de,"PptA is required to synthesize the immunotoxic compound gliotoxin, DHN-melanin, immunotoxic secondary metabolites are absent in pptA null mutant. The pptA null mutant stimulated dendritic cells to produce immunomodulatory cytokines and enhances phagolysosome acidification.",A Johns 2017,2017,4 genes,Johns-2017-A Nonredundant Phosphopantetheinyl,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9728,PHI:7335,UniProt,B0XVQ6,GenBank,EDP55264,,,A1163,pksP,,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,polyketide synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28720735,PubMed,10.1128/mBio.01504-16,MBio. 2017 Jul 18;8(4). pii: e01504-16,axel.brakhage@leibniz-hki.de,"PptA is required to synthesize the immunotoxic compound gliotoxin, DHN-melanin, immunotoxic secondary metabolites are absent in pptA null mutant. The pptA null mutant stimulated dendritic cells to produce immunomodulatory cytokines and enhances phagolysosome acidification.",A Johns 2017,2017,4 genes,Johns-2017-A Nonredundant Phosphopantetheinyl,BATCH_072A,2017-08-01,MC,,,,,,,,,,,,,
,,Record 9729,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PRP27-HopAI,,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,no,yes,,,reduced,,wild type,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9730,PHI:7337,UniProt,Q87W07,GenBank,AAO58206,,,DC3000,HopI1,,PRP27-HopI1,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector protein,,,MAP kinase pathway,effector (plant avirulence determinant),,no,no,,,wild type,,wild type,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9731,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PRP27-HopAI,,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,Ku80,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,no,yes,,,reduced,,wild type,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9732,PHI:7337,UniProt,Q87W07,GenBank,AAO58206,,,DC3000,HopI1,,PRP27-HopI1,,,,,318829,Magnaporthe oryzae,,Ku80,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,MAP kinase pathway,effector (plant avirulence determinant),,no,no,,,wild type,,wild type,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9733,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PTrpC-HopAI,,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,,,,,reduced,,wild type,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9734,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PTrpC-HopAI (TA1),,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,KV103,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,,,,,reduced,,,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9735,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PRP27-HopAI (RA11),,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,KV103,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,,,,,,,,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9736,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PBAS1-HopAI (BA1),,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,KV103,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,,,,,reduced,,,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9737,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PMIR1-HopAI (MA3),,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,KV103,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,,,,,,,,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9738,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PTrpC-HopAI (TA1),,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,KV103,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,,,,,reduced,,,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9739,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PRP27-HopAI (RA11),,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,KV103,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,,,,,,,,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9740,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PBAS1-HopAI (BA1),,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,KV103,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,,,,,reduced,,,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9741,PHI:7336,UniProt,Q888W0,GenBank,AAO54440,,,DC3000,HopAI,,PMIR1-HopAI (MA3),,Mps1,UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,KV103,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,"effector protein, phosphothreonine lyase",,,MAP kinase pathway,effector (plant avirulence determinant),,,,,,,,,,no,sorbitol,sorbitol: CHEBI:30911,,,,,heterologous expression,,,YVS,28799700,PubMed,10.1111/1462-2920.13884,Environ Microbiol. 2017 Aug 11,jinrong@purdue.edu,"Mps1 was the major intracellular target of HopAI when it was overexpressed, and MAP kinase signaling was important for cell-to-cell movement of invasive hyphae in M. oryzae.",X Zhang 2017,2017,2 genes,Zhang-2017-Expression of HopAI interferes with,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9742,PHI:7338,UniProt,Q99XV0,GenBank,AAK34694,,,SF370,emm1/M1,,M1ΔB1ΔB2,,,,,1314,Streptococcus pyogenes,,serotype M1 strain 5448,necrotizing fasciitis; toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,peritoneum,"surface-associated protein, virulence factor",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28784982,PubMed,10.1038/s41564-017-0005-6,Nat Microbiol. 2017 Aug 7,pghosh@ucsd.edu,"M1 activated the NLRP3 inflammasome in a scenario involving K+ efflux, activation of caspase-1, processing of pro-IL-1beta and secretion of mature IL-1beta, all accompanied by macrophage pyroptosis.",J A Valderrama 2017,2017,3 genes,Valderrama-2017-Group A streptococcal M protei,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9743,PHI:7339,UniProt,P0C0I3,GenBank,AAK33267,,,SF370,SLO,,,,,,,1314,Streptococcus pyogenes,,serotype M1 strain 5448,necrotizing fasciitis; toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,peritoneum,streptolysin O,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28784982,PubMed,10.1038/s41564-017-0005-6,Nat Microbiol. 2017 Aug 7,pghosh@ucsd.edu,"M1 activated the NLRP3 inflammasome in a scenario involving K+ efflux, activation of caspase-1, processing of pro-IL-1beta and secretion of mature IL-1beta, all accompanied by macrophage pyroptosis.",J A Valderrama 2017,2017,3 genes,Valderrama-2017-Group A streptococcal M protei,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9744,PHI:7338,UniProt,Q99XV0,GenBank,AAK34694,,,SF370,emm1/M1,,,,,,,1314,Streptococcus pyogenes,,serotype M1 strain 5448,necrotizing fasciitis; toxic shock syndrome,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,"surface-associated protein, virulence factor",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28784982,PubMed,10.1038/s41564-017-0005-6,Nat Microbiol. 2017 Aug 7,pghosh@ucsd.edu,"M1 activated the NLRP3 inflammasome in a scenario involving K+ efflux, activation of caspase-1, processing of pro-IL-1beta and secretion of mature IL-1beta, all accompanied by macrophage pyroptosis.",J A Valderrama 2017,2017,3 genes,Valderrama-2017-Group A streptococcal M protei,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9745,PHI:7339,UniProt,P0C0I3,GenBank,AAK33267,,,SF370,SLO,,,,,,,1314,Streptococcus pyogenes,,serotype M1 strain 5448,necrotizing fasciitis; toxic shock syndrome,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,streptolysin O,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28784982,PubMed,10.1038/s41564-017-0005-6,Nat Microbiol. 2017 Aug 7,pghosh@ucsd.edu,"M1 activated the NLRP3 inflammasome in a scenario involving K+ efflux, activation of caspase-1, processing of pro-IL-1beta and secretion of mature IL-1beta, all accompanied by macrophage pyroptosis.",J A Valderrama 2017,2017,3 genes,Valderrama-2017-Group A streptococcal M protei,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9746,PHI:7340,UniProt,J7M2U8,GenBank,BAM29749,,,M1 476,SpyA,chromosome 1,,,,,,1314,Streptococcus pyogenes,,serotype M1 strain 5448,necrotizing fasciitis; toxic shock syndrome,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,C3 family ADP-ribosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28784982,PubMed,10.1038/s41564-017-0005-6,Nat Microbiol. 2017 Aug 7,pghosh@ucsd.edu,"M1 activated the NLRP3 inflammasome in a scenario involving K+ efflux, activation of caspase-1, processing of pro-IL-1beta and secretion of mature IL-1beta, all accompanied by macrophage pyroptosis.",J A Valderrama 2017,2017,3 genes,Valderrama-2017-Group A streptococcal M protei,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9747,PHI:7341,UniProt,A0A191TCF2,GenBank,ANI86041,,,FWDRC-HC138,htrA,,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28770008,PubMed,10.1186/s13099-017-0189-6,Gut Pathog. 2017 Jul 25;9:40,Nicole.Tegtmeyer@fau.de,"Overexpression of HtrA does not afect host cell binding, IL-8 secretion and verexpression of HtrA enhances disruption of cell-to-cell junctions by H. pylori.",A Harrer 2017,2017,1 gene,Harrer-2017-Overexpression of serine protease,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9748,PHI:7341,UniProt,A0A191TCF2,GenBank,ANI86041,,,FWDRC-HC138,htrA,,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),MKN28 cell line,,,epithelial cell,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,yes,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28770008,PubMed,10.1186/s13099-017-0189-6,Gut Pathog. 2017 Jul 25;9:40,Nicole.Tegtmeyer@fau.de,"Overexpression of HtrA does not afect host cell binding, IL-8 secretion and verexpression of HtrA enhances disruption of cell-to-cell junctions by H. pylori.",A Harrer 2017,2017,1 gene,Harrer-2017-Overexpression of serine protease,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9749,PHI:7342,UniProt,Q48252,GenBank,AF282853_14,,,CCUG 17874; NCTC 11638,CagE,,,,,,,210,Helicobacter pylori,,AB31,gastric infection,primates,9606,Homo sapiens (related: human),MKN28 cell line,,,gastric epithelium cell line,CAG pathogenicity island protein,,,signalling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28759055,PubMed,10.1371/journal.pone.0182144,PLoS One. 2017 Jul 28;12(7):e0182144,rob.delahay@nottingham.ac.uk,The study indicated a role for the Tfs3 T4SS in CtkA-mediated pro-inflammatory signalling by H. pylori and identified CtkA as a likely Tfs3 T4SS secretion substrate.,M N Alandiyjany 2017,2017,2 genes,Alandiyjany-2017-A role for the tfs3 ICE-encod,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9750,PHI:7342,UniProt,Q48252,GenBank,AF282853_14,,,CCUG 17874; NCTC 11638,CagE,,,,,,,210,Helicobacter pylori,,10A,gastric infection,primates,9606,Homo sapiens (related: human),MKN28 cell line,,,gastric epithelium cell line,CAG pathogenicity island protein,,,signalling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28759055,PubMed,10.1371/journal.pone.0182144,PLoS One. 2017 Jul 28;12(7):e0182144,rob.delahay@nottingham.ac.uk,The study indicated a role for the Tfs3 T4SS in CtkA-mediated pro-inflammatory signalling by H. pylori and identified CtkA as a likely Tfs3 T4SS secretion substrate.,M N Alandiyjany 2017,2017,2 genes,Alandiyjany-2017-A role for the tfs3 ICE-encod,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9751,PHI:7342,UniProt,Q48252,GenBank,AF282853_14,,,CCUG 17874; NCTC 11638,CagE,,,,,,,210,Helicobacter pylori,,64,gastric infection,primates,9606,Homo sapiens (related: human),MKN28 cell line,,,gastric epithelium cell line,CAG pathogenicity island protein,,,signalling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28759055,PubMed,10.1371/journal.pone.0182144,PLoS One. 2017 Jul 28;12(7):e0182144,rob.delahay@nottingham.ac.uk,The study indicated a role for the Tfs3 T4SS in CtkA-mediated pro-inflammatory signalling by H. pylori and identified CtkA as a likely Tfs3 T4SS secretion substrate.,M N Alandiyjany 2017,2017,2 genes,Alandiyjany-2017-A role for the tfs3 ICE-encod,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9752,PHI:7342,UniProt,Q48252,GenBank,AF282853_14,,,CCUG 17874; NCTC 11638,CagE,,,,,,,210,Helicobacter pylori,,AB5,gastric infection,primates,9606,Homo sapiens (related: human),MKN28 cell line,,,gastric epithelium cell line,CAG pathogenicity island protein,,,signalling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28759055,PubMed,10.1371/journal.pone.0182144,PLoS One. 2017 Jul 28;12(7):e0182144,rob.delahay@nottingham.ac.uk,The study indicated a role for the Tfs3 T4SS in CtkA-mediated pro-inflammatory signalling by H. pylori and identified CtkA as a likely Tfs3 T4SS secretion substrate.,M N Alandiyjany 2017,2017,2 genes,Alandiyjany-2017-A role for the tfs3 ICE-encod,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9753,PHI:7342,UniProt,Q48252,GenBank,AF282853_14,,,CCUG 17874; NCTC 11638,CagE,,AB5ΔvirB9ΔcagE:ctkA,,,,PHI:7343,210,Helicobacter pylori,,AB5,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,CAG pathogenicity island protein,,,signalling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28759055,PubMed,10.1371/journal.pone.0182144,PLoS One. 2017 Jul 28;12(7):e0182144,rob.delahay@nottingham.ac.uk,The study indicated a role for the Tfs3 T4SS in CtkA-mediated pro-inflammatory signalling by H. pylori and identified CtkA as a likely Tfs3 T4SS secretion substrate.,M N Alandiyjany 2017,2017,2 genes,Alandiyjany-2017-A role for the tfs3 ICE-encod,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9754,PHI:7343,UniProt,I9QLN0,GenBank,EJB34014,,,NQ4076,virB9,,AB5ΔvirB9ΔcagE:ctkA,,,,PHI:7342,210,Helicobacter pylori,,AB5,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,required for substrate selection and assembly of the T4SS complex,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28759055,PubMed,10.1371/journal.pone.0182144,PLoS One. 2017 Jul 28;12(7):e0182144,rob.delahay@nottingham.ac.uk,The study indicated a role for the Tfs3 T4SS in CtkA-mediated pro-inflammatory signalling by H. pylori and identified CtkA as a likely Tfs3 T4SS secretion substrate.,M N Alandiyjany 2017,2017,2 genes,Alandiyjany-2017-A role for the tfs3 ICE-encod,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9755,PHI:7342,UniProt,Q48252,GenBank,AF282853_14,,,CCUG 17874; NCTC 11638,CagE,,AB5ΔcagE:ctkA,,,,,210,Helicobacter pylori,,AB5,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,CAG pathogenicity island protein,,,signalling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28759055,PubMed,10.1371/journal.pone.0182144,PLoS One. 2017 Jul 28;12(7):e0182144,rob.delahay@nottingham.ac.uk,The study indicated a role for the Tfs3 T4SS in CtkA-mediated pro-inflammatory signalling by H. pylori and identified CtkA as a likely Tfs3 T4SS secretion substrate.,M N Alandiyjany 2017,2017,2 genes,Alandiyjany-2017-A role for the tfs3 ICE-encod,BATCH_072B,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9756,PHI:7344,UniProt,A0A0H2XG07,GenBank,ABD21364,,,USA300_FPR3757,PurA,,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,adenylosuccinate synthetase,,,de novo biosynthetic pathway for purines,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9757,PHI:7345,UniProt,Q2FFI7,GenBank,ABD20399,,,USA300_FPR3757,PurB,,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,adenylosuccinate lyase,,,de novo biosynthetic pathway for purines,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9758,PHI:7346,UniProt,A0A0H2XK89,GenBank,ABD22723,,,USA300_FPR3757,PabA,,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,"para-aminobenzoate synthase, glutamine amidotransferase, component II",,,tetrahydrofolate biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9759,PHI:7347,UniProt,A0A0Z4HP95,GenBank,CXR53204,,,st1257,PabB,,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,"para-aminobenzoate synthase, glutamine amidotransferase, component I",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9760,PHI:7348,UniProt,A0A0H3KBG6,GenBank,BAF66956,,,Newman,PabC,,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,4-amino-4-deoxychorismate lyase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9761,PHI:7344,UniProt,A0A0H2XG07,GenBank,ABD21364,,,USA300_FPR3757,PurA,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,adenylosuccinate synthetase,,,de novo biosynthetic pathway for purines,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9762,PHI:7345,UniProt,Q2FFI7,GenBank,ABD20399,,,USA300_FPR3757,PurB,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,adenylosuccinate lyase,,,de novo biosynthetic pathway for purines,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9763,PHI:7346,UniProt,A0A0H2XK89,GenBank,ABD22723,,,USA300_FPR3757,PabA,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,"para-aminobenzoate synthase, glutamine amidotransferase, component II",,,tetrahydrofolate biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9764,PHI:7349,UniProt,A0A0H2XIJ3,GenBank,ABD22514,,,USA300_FPR3757,atl,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,autolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9765,PHI:7350,UniProt,Q2FK71,GenBank,ABD22914,,,USA300_FPR3757,murQ,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,N-acetylmuramic acid-6-phosphate etherase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9766,PHI:7351,UniProt,A0A0H2XGW2,GenBank,ABD21797,,,USA300_FPR3757,araC,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,transcription regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9767,PHI:7352,UniProt,Q2FI79,GenBank,ABD21664,,,USA300_FPR3757,mecA,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,adaptor protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9768,PHI:7353,UniProt,Q2FH26,GenBank,ABD22597,,,USA300_FPR3757,odhB,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,dihydrolipoamide succinyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9769,PHI:7354,UniProt,A0A0H2XI72,GenBank,ABD22618,,,USA300_FPR3757,lipA,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,triacylglycerol lipase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9770,PHI:7346,UniProt,A0A0H2XK89,GenBank,ABD22723,,,USA300_FPR3757,PabA,,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,kidney,"para-aminobenzoate synthase, glutamine amidotransferase, component II",,,tetrahydrofolate biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,28808156,PubMed,10.1128/IAI.00337-17,Infect Immun.2017 Aug 14. pii: IAI.00337-17,s.foster@sheffield.ac.uk,"The ability of purine biosynthesis mutants to grow in nutrient rich media suggested that purA and purB have a requirement for nutrients not readily available in human serum, whole blood and the live zebrafish.",J Connolly 2017,2017,12 genes,Connolly-2017-The identification of Staphyloco,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9771,PHI:7355,UniProt,A0A0F6B1M3,GenBank,ACY88409,,,14028S,ugtL,,,,PhoQ,UniProt: D0ZV89; GenBank: ACY87894,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneum,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28851823,PubMed,10.1126/scisignal.aan6284,Sci Signal.2017 Aug 29;10(494). pii: eaan6284,eduardo.groisman@yale.edu,"When Salmonella experiences mildly acidic pH, PhoP activation requires PhoQ to detect pH and UgtL to amplify the PhoQ response.",J Choi 2017,2017,2 genes,Choi-2017-Activation of master virulence regul,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9772,PHI:7356,UniProt,D0ZV89,GenBank,ACY87894,,,14028S,PhoQ,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneum,pH sensing,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28851823,PubMed,10.1126/scisignal.aan6284,Sci Signal.2017 Aug 29;10(494). pii: eaan6284,eduardo.groisman@yale.edu,"When Salmonella experiences mildly acidic pH, PhoP activation requires PhoQ to detect pH and UgtL to amplify the PhoQ response.",J Choi 2017,2017,2 genes,Choi-2017-Activation of master virulence regul,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9773,PHI:7355,UniProt,A0A0F6B1M3,GenBank,ACY88409,,,14028S,ugtL,,,,PhoQ,UniProt: D0ZV89; GenBank: ACY87894,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneum,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28851823,PubMed,10.1126/scisignal.aan6284,Sci Signal.2017 Aug 29;10(494). pii: eaan6284,eduardo.groisman@yale.edu,"When Salmonella experiences mildly acidic pH, PhoP activation requires PhoQ to detect pH and UgtL to amplify the PhoQ response.",J Choi 2017,2017,2 genes,Choi-2017-Activation of master virulence regul,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9774,PHI:7356,UniProt,D0ZV89,GenBank,ACY87894,,,14028S,PhoQ,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,peritoneum,pH sensing,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28851823,PubMed,10.1126/scisignal.aan6284,Sci Signal.2017 Aug 29;10(494). pii: eaan6284,eduardo.groisman@yale.edu,"When Salmonella experiences mildly acidic pH, PhoP activation requires PhoQ to detect pH and UgtL to amplify the PhoQ response.",J Choi 2017,2017,2 genes,Choi-2017-Activation of master virulence regul,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9775,PHI:7357,UniProt,Q6NF16,GenBank,CAE50621,,,NCTC13129,DIP2093,,,,,,,1717,Corynebacterium diphtheriae,257309,NCTC 13129,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,putative adhesin of the serine aspartate repeat (Sdr) protein family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28535857,PubMed,10.1099/mic.0.000467,Microbiology.2017 May;163(5):692-701,andreas.burkovski@fau.de,"Compared to the parental strain, a DIP2093 mutant RN generated in this study was attenuated in its ability to bind to type I collagen, to adhere to and invade epithelial cells, as well as to survive within macrophages.",R S Peixoto 2017,2017,1 gene,Peixoto-2017-Functional characterization of th,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9776,PHI:7357,UniProt,Q6NF16,GenBank,CAE50621,,,NCTC13129,DIP2093,,,,,,,1717,Corynebacterium diphtheriae,257309,NCTC 13129,diphtheria,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,joint,putative adhesin of the serine aspartate repeat (Sdr) protein family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28535857,PubMed,10.1099/mic.0.000467,Microbiology.2017 May;163(5):692-701,andreas.burkovski@fau.de,"Compared to the parental strain, a DIP2093 mutant RN generated in this study was attenuated in its ability to bind to type I collagen, to adhere to and invade epithelial cells, as well as to survive within macrophages.",R S Peixoto 2017,2017,1 gene,Peixoto-2017-Functional characterization of th,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9777,PHI:7358,UniProt,Q86ZB5,GenBank,AAO59283,,,,KLP7,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3827,Cicer arietinum (related: Chickpea),cv. P-256,,,leaf,kinesin-like protein,,,,reduced virulence,,,yes,,,,,,reduced,no,,,,,,,gene disruption; gene complementation,,,YVS,28878341,PubMed,10.1038/s41598-017-09409-5,Sci Rep.2017 Sep 6;7(1):10664,akjohri14@yahoo.com,The mutant was also defective in secretion of oxalic acid (OA) and exhibited reduced activities of polygalacturonase (PG) and pectin methyl esterases (PME).,P Tayal 2017,2017,1 gene,Tayal-2017-A Botrytis cinerea KLP-7 Kinesin ac,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9778,PHI:7359,UniProt,P9WMH5,GenBank,CCP44440,,,H37Rv,Cmr,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),,,,lung; spleen,member of the CRP/FNR super-family of transcription regulator and a redox sensor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28482027,PubMed,10.1093/nar/gkx406,Nucleic Acids Res.2017 Jun 20;45(11):6600-6612,laura.smith@dmu.ac.uk,"A cmr mutant was better able to survive a nitrosative stress challenge but was attenuated in a mouse aerosol infection model and the complemented mutant exhibited a ~2-fold increase in cmr expression, which led to increased sensitivity to nitrosative stress.",L J Smith 2017,2017,1 gene,Smith-2017-Cmr is a redox-responsive regulator,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9779,PHI:7360,,no data found,,,,,,IpfA,,,,,,PHI:7361; PHI:7362; PHI:7363,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9780,PHI:7361,,no data found,,,,,,IpfB,,,,,,PHI:7360; PHI:7362; PHI:7363,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9781,PHI:7362,,no data found,,,,,,IpfC,,,,,,PHI:7360; PHI:7361; PHI:7363,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9782,PHI:7363,,no data found,,,,,,IpfD,,,,,,PHI:7360; PHI:7361; PHI:7362,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9783,PHI:7360,,no data found,,,,,,IpfA,,,,,,PHI:7361; PHI:7362; PHI:7363,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,ileum,plasmid-encoded chaperone-usher fimbriae,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9784,PHI:7361,,no data found,,,,,,IpfB,,,,,,PHI:7360; PHI:7362; PHI:7363,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,ileum,plasmid-encoded chaperone-usher fimbriae,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9785,PHI:7362,,no data found,,,,,,IpfC,,,,,,PHI:7360; PHI:7361; PHI:7363,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,ileum,plasmid-encoded chaperone-usher fimbriae,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9786,PHI:7363,,no data found,,,,,,IpfD,,,,,,PHI:7360; PHI:7361; PHI:7362,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,ileum,plasmid-encoded chaperone-usher fimbriae,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9787,PHI:7364,,no data found,,,,,,KlfA,,,,,,PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9788,PHI:7365,,no data found,,,,,,KlfB,,,,,,PHI:7364; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9789,PHI:7366,,no data found,,,,,,KlfC,,,,,,PHI:7364; PHI:7365; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9790,PHI:7367,,no data found,,,,,,KlfD,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9791,PHI:7368,,no data found,,,,,,KlfE,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9792,PHI:7369,,no data found,,,,,,KlfF,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9793,PHI:7370,,no data found,,,,,,KlfG,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9794,PHI:7371,,no data found,,,,,,KlfH,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9795,PHI:7372,,no data found,,,,,,KlfI,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9796,PHI:7373,,no data found,,,,,,KlfJ,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9797,PHI:7374,,no data found,,,,,,KlfK,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9798,PHI:7375,,no data found,,,,,,KlfL,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; ileum,plasmid-encoded chaperone-usher fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9799,PHI:7360,,no data found,,,,,,IpfA,,,,,,PHI:7361; PHI:7362; PHI:7363,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9800,PHI:7361,,no data found,,,,,,IpfB,,,,,,PHI:7360; PHI:7362; PHI:7363,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9801,PHI:7362,,no data found,,,,,,IpfC,,,,,,PHI:7360; PHI:7361; PHI:7363,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9802,PHI:7363,,no data found,,,,,,IpfD,,,,,,PHI:7360; PHI:7361; PHI:7362,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9803,PHI:7364,,no data found,,,,,,KlfA,,,,,,PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9804,PHI:7365,,no data found,,,,,,KlfB,,,,,,PHI:7364; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9805,PHI:7366,,no data found,,,,,,KlfC,,,,,,PHI:7364; PHI:7365; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9806,PHI:7367,,no data found,,,,,,KlfD,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9807,PHI:7368,,no data found,,,,,,KlfE,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9808,PHI:7369,,no data found,,,,,,KlfF,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9809,PHI:7370,,no data found,,,,,,KlfG,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7371; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9810,PHI:7371,,no data found,,,,,,KlfH,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7372; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9811,PHI:7372,,no data found,,,,,,KlfI,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7373; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9812,PHI:7373,,no data found,,,,,,KlfJ,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7374; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9813,PHI:7374,,no data found,,,,,,KlfK,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7375,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9814,PHI:7375,,no data found,,,,,,KlfL,,,,,,PHI:7364; PHI:7365; PHI:7366; PHI:7367; PHI:7368; PHI:7369; PHI:7370; PHI:7371; PHI:7372; PHI:7373; PHI:7374,28901,Salmonella enterica,595,subsp. enterica serovar Infantis strain 119944,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,duodenum; jejunum; ileum; cecum; colon; liver,plasmid-encoded chaperone-usher fimbriae,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28817673,PubMed,10.1371/journal.ppat.1006559,PLoS Pathog.2017 Aug 17;13(8):e1006559,Ohad.Gal-Mor@sheba.health.gov.il,"It was suggested that by coordinating fimbriae expression according to the host temperature, Salmonella can express a different set of fimbriae in mammalian vs. avian hosts and by that shape the outcome of the infection.",G Aviv 2017,2017,16 genes,Aviv-2017-The plasmid-encoded Ipf and Klf fimb,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9815,PHI:7376,UniProt,J4URT3,GenBank,EJP68242,,,ARSEF 2860,Blys2,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,LysM effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; heterologous complementation,,,YVS,28873459,PubMed,10.1371/journal.ppat.1006604,PLoS Pathog.2017 Sep 5;13(9):e1006604,cswang@sibs.ac.cn,"Relative to the wild-type strain, loss of Blys2 or Blys5 could impair fungal propagation in insect hemocoels and lead to the upregulation of antifungal gene in insects and the virulence defects of ΔBlys2 and ΔBlys5 could be fully restored by complementation with the Slp1 effector from the rice blast fungus Magnaporthe oryzae.",K Cen 2017,2017,6 genes,Cen-2017-Divergent LysM effectors contribute t,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9816,PHI:7377,UniProt,J5JHE8,GenBank,EJP65083,,,ARSEF 2860,Blys4,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,lysin motif (LysM) containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; heterologous complementation,,,YVS,28873459,PubMed,10.1371/journal.ppat.1006604,PLoS Pathog.2017 Sep 5;13(9):e1006604,cswang@sibs.ac.cn,"Relative to the wild-type strain, loss of Blys2 or Blys5 could impair fungal propagation in insect hemocoels and lead to the upregulation of antifungal gene in insects and the virulence defects of ΔBlys2 and ΔBlys5 could be fully restored by complementation with the Slp1 effector from the rice blast fungus Magnaporthe oryzae.",K Cen 2017,2017,6 genes,Cen-2017-Divergent LysM effectors contribute t,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9817,PHI:7378,UniProt,J5J7Y8,GenBank,EJP62518,,,ARSEF 2860,Blys5,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,LysM effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; heterologous complementation,,,YVS,28873459,PubMed,10.1371/journal.ppat.1006604,PLoS Pathog.2017 Sep 5;13(9):e1006604,cswang@sibs.ac.cn,"Relative to the wild-type strain, loss of Blys2 or Blys5 could impair fungal propagation in insect hemocoels and lead to the upregulation of antifungal gene in insects and the virulence defects of ΔBlys2 and ΔBlys5 could be fully restored by complementation with the Slp1 effector from the rice blast fungus Magnaporthe oryzae.",K Cen 2017,2017,6 genes,Cen-2017-Divergent LysM effectors contribute t,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9818,PHI:7379,UniProt,J5JFB6,GenBank,EJP62326,,,ARSEF 2860,Blys6,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,lysin motif (LysM) containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; heterologous complementation,,,YVS,28873459,PubMed,10.1371/journal.ppat.1006604,PLoS Pathog.2017 Sep 5;13(9):e1006604,cswang@sibs.ac.cn,"Relative to the wild-type strain, loss of Blys2 or Blys5 could impair fungal propagation in insect hemocoels and lead to the upregulation of antifungal gene in insects and the virulence defects of ΔBlys2 and ΔBlys5 could be fully restored by complementation with the Slp1 effector from the rice blast fungus Magnaporthe oryzae.",K Cen 2017,2017,6 genes,Cen-2017-Divergent LysM effectors contribute t,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9819,PHI:7380,UniProt,J4VU52,GenBank,EJP62055,,,ARSEF 2860,Blys7,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,lysin motif (LysM) containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; heterologous complementation,,,YVS,28873459,PubMed,10.1371/journal.ppat.1006604,PLoS Pathog.2017 Sep 5;13(9):e1006604,cswang@sibs.ac.cn,"Relative to the wild-type strain, loss of Blys2 or Blys5 could impair fungal propagation in insect hemocoels and lead to the upregulation of antifungal gene in insects and the virulence defects of ΔBlys2 and ΔBlys5 could be fully restored by complementation with the Slp1 effector from the rice blast fungus Magnaporthe oryzae.",K Cen 2017,2017,6 genes,Cen-2017-Divergent LysM effectors contribute t,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9820,PHI:7381,UniProt,J4KL74,GenBank,EJP61709,,,ARSEF 2860,Blys8,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,lysin motif (LysM) containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; heterologous complementation,,,YVS,28873459,PubMed,10.1371/journal.ppat.1006604,PLoS Pathog.2017 Sep 5;13(9):e1006604,cswang@sibs.ac.cn,"Relative to the wild-type strain, loss of Blys2 or Blys5 could impair fungal propagation in insect hemocoels and lead to the upregulation of antifungal gene in insects and the virulence defects of ΔBlys2 and ΔBlys5 could be fully restored by complementation with the Slp1 effector from the rice blast fungus Magnaporthe oryzae.",K Cen 2017,2017,6 genes,Cen-2017-Divergent LysM effectors contribute t,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9821,PHI:7382,UniProt,Q8ZPY9,GenBank,AAL20168,,,LT2; SGSC 1412; ATCC 700720,SopF,,ΔsopF::kan,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; spleen; liver,T3SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28887382,PubMed,10.1074/mcp.RA117.000230,Mol Cell Proteomics.2017 Sep 8. pii: mcp.000230.2017,xiaoyun.liu@pku.edu.cn,Deletion of sopF led to a replication defect of Salmonella in RAW264.7 macrophages but did not affect bacterial virulence during infection of HeLa cells.,S Cheng 2017,2017,1 gene,Cheng-2017-Identification of a novel Salmonell,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9822,PHI:7382,UniProt,Q8ZPY9,GenBank,AAL20168,,,LT2; SGSC 1412; ATCC 700720,SopF,,ΔsopF::kan,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,T3SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28887382,PubMed,10.1074/mcp.RA117.000230,Mol Cell Proteomics.2017 Sep 8. pii: mcp.000230.2017,xiaoyun.liu@pku.edu.cn,Deletion of sopF led to a replication defect of Salmonella in RAW264.7 macrophages but did not affect bacterial virulence during infection of HeLa cells.,S Cheng 2017,2017,1 gene,Cheng-2017-Identification of a novel Salmonell,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9823,PHI:7383,UniProt,G0Z025,GenBank,AEI60186,,,B40,SElX,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,staphylococcal enterotoxin-like toxin X,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28880920,PubMed,10.1371/journal.ppat.1006461,PLoS Pathog.2017 Sep 7;13(9):e1006461,ross.fitzgerald@roslin.ed.ac.uk,It was demonstrated that the neutrophil-binding activity rather than superantigenicity is responsible for the SElX-dependent virulence observed in a necrotizing pneumonia rabbit model of infection.,S W Tuffs 2017,2017,1 gene,Tuffs-2017-The Staphylococcus aureus superanti,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9824,PHI:7383,UniProt,G0Z025,GenBank,AEI60186,,,B40,SElX,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,trachea,staphylococcal enterotoxin-like toxin X,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28880920,PubMed,10.1371/journal.ppat.1006461,PLoS Pathog.2017 Sep 7;13(9):e1006461,ross.fitzgerald@roslin.ed.ac.uk,It was demonstrated that the neutrophil-binding activity rather than superantigenicity is responsible for the SElX-dependent virulence observed in a necrotizing pneumonia rabbit model of infection.,S W Tuffs 2017,2017,1 gene,Tuffs-2017-The Staphylococcus aureus superanti,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9825,PHI:7384,,no data found,,,,,,VvpM,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),,,,ileum,extracellular metalloprotease,,,inflammosome pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28848713,PubMed,10.3389/fcimb.2017.00352,Front Cell Infect Microbiol.2017 Aug 11;7:352,hjhan@snu.ac.kr,VvpM is a major virulence factor of V. vulnificus responsible for IL-1ß production coupled with necroticcelldeath.,S J Lee 2017,2017,1 gene,Lee-2017-A Vibrio vulnificus VvpM Induces IL-1,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9826,PHI:7385,UniProt,G4MZL7,GenBank,EHA54576,,,70-15,MoVps17,chromosome 2,,,MoVps5,UniProt: G4MLL2; GenBank: EHA56845,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,sorting nexin (SNX) and a component of the retromer,,,intracellular trafficking pathway,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28836715,PubMed,10.1111/1462-2920.13896,Environ Microbiol.2017 Aug 24,wangzh@fafu.edu.cn,"MoVps17 was required for the budding of endosome, vacuolar organization and normal endocytosis.",H Zheng 2017,2017,1 gene,Zheng-2017-Sorting nexin (MoVps17) is required,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9827,PHI:7385,UniProt,G4MZL7,GenBank,EHA54576,,,70-15,MoVps17,chromosome 2,,,MoVps5,UniProt: G4MLL2; GenBank: EHA56845,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,sorting nexin (SNX) and a component of the retromer,,,intracellular trafficking pathway,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28836715,PubMed,10.1111/1462-2920.13896,Environ Microbiol.2017 Aug 24,wangzh@fafu.edu.cn,"MoVps17 was required for the budding of endosome, vacuolar organization and normal endocytosis.",H Zheng 2017,2017,1 gene,Zheng-2017-Sorting nexin (MoVps17) is required,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9828,PHI:7386,UniProt,Q60048,GenBank,AAA25275,,,Lm74,CadA,,,,,,,1639,Listeria monocytogenes,169963,serotype 1/2a strain EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,cadmium-dependent efflux pump regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28368435,PubMed,10.1093/infdis/jix118,J Infect Dis.2017 May 1;215(9):1468-1479,didier@ibmc.up.pt,"L.monocytogenes used CadC to repress lspB expression during infection to avoid LpeA exposure to the host immune system, diminishing inflammatory cytokine expression and promoting intramacrophagic survival and virulence.",RPombinho 2017,2017,2 genes,Pombinho-2017-Listeria monocytogenes CadC regu,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9829,PHI:7387,UniProt,Q56405,GenBank,AAA25276,,,Lm74,CadC,,,,,,,1639,Listeria monocytogenes,169963,serotype 1/2a strain EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,cadmium-dependent efflux pump regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28368435,PubMed,10.1093/infdis/jix118,J Infect Dis.2017 May 1;215(9):1468-1479,didier@ibmc.up.pt,"L.monocytogenes used CadC to repress lspB expression during infection to avoid LpeA exposure to the host immune system, diminishing inflammatory cytokine expression and promoting intramacrophagic survival and virulence.",RPombinho 2017,2017,2 genes,Pombinho-2017-Listeria monocytogenes CadC regu,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9830,PHI:7386,UniProt,Q60048,GenBank,AAA25275,,,Lm74,CadA,,,,,,PHI:7387,1639,Listeria monocytogenes,169963,serotype 1/2a strain EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,cadmium-dependent efflux pump regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28368435,PubMed,10.1093/infdis/jix118,J Infect Dis.2017 May 1;215(9):1468-1479,didier@ibmc.up.pt,"L.monocytogenes used CadC to repress lspB expression during infection to avoid LpeA exposure to the host immune system, diminishing inflammatory cytokine expression and promoting intramacrophagic survival and virulence.",RPombinho 2017,2017,2 genes,Pombinho-2017-Listeria monocytogenes CadC regu,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9831,PHI:7387,UniProt,Q56405,GenBank,AAA25276,,,Lm74,CadC,,,,,,PHI:7386,1639,Listeria monocytogenes,169963,serotype 1/2a strain EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,cadmium-dependent efflux pump regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28368435,PubMed,10.1093/infdis/jix118,J Infect Dis.2017 May 1;215(9):1468-1479,didier@ibmc.up.pt,"L.monocytogenes used CadC to repress lspB expression during infection to avoid LpeA exposure to the host immune system, diminishing inflammatory cytokine expression and promoting intramacrophagic survival and virulence.",RPombinho 2017,2017,2 genes,Pombinho-2017-Listeria monocytogenes CadC regu,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9832,PHI:7388,,no data found,JGI,Lema_T071490,,,,Sap1,,,,,,,5022,Leptosphaeria maculans,,D5,blackleg (rapeseed),eudicots,3708,Brassica napus (related: rape),cv. Westar,,,cotyledon,Sit4-associated protein,,,,reduced virulence,,,,yes,,wild type,,reduced; aberrant,wild type,no,,,,,,,gene mutation; gene complementation,,,YVS,28840344,PubMed,10.1007/s00284-017-1338-3,Curr Microbiol.2017 Aug 24,alexander.idnurm@unimelb.edu.au,"The mutant had normal spore production and spore germination, but altered hyphal branching, suggesting that nutrient signaling is impaired in the strain.",A S Urquhart 2017,2017,1 gene,Urquhart-2017-Sit4-Associated Protein is Requi,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9833,PHI:7389,UniProt,A0A0H2ZCE5,GenBank,ABJ12036,,,UCBPP-PA14,mlaA/vacJ,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; blood,outer membrane lipoprotein,,,VacJ/Mla pathway,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); ethylenediaminetetraacetic acid (EDTA); colistin; polymyxin B,SDS: CHEBI:8984; EDTA: CHEBI:64758; colistin: CHEBI:37943; polymyxin B: CHEBI:8309,,,,,gene mutation; gene complementation,,,YVS,28844103,PubMed,10.1007/s00109-017-1579-4,J Mol Med (Berl).2017 Aug 26,vnizet@ucsd.edu,"When exposed to human whole blood and serum complement, the vacJ- mutant was killed more rapidly when compared to the wild-type parent strain and complemented mutant.",J Munguia 2017,2017,1 gene,Munguia-2017-The Mla pathway is critical for P,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9834,PHI:7390,UniProt,Q9HWH2,GenBank,AAG07596,,,PAO1,phzM,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,lung,probable phenazine-specific methyltransferase required for pyocyanin biosynthesis,,,EIF2AK4-EIF2S1-ATF4 autophagy pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,27159636,PubMed,10.1080/15548627.2016.1170256,Autophagy.2016 Jun 2;12(6):1015-28,chgzou@ynu.edu.cn,"When comparing the wild-type and pyocyanin-deficient strains of P. aeruginosa, it was found that lack of pyocyanin caused a higher mortality rate and induced more extensive alveolar wall thickening in the pulmonary airways of rats.",Z S Yang 2016,2016,1 gene,Yang-2016-Pseudomonas toxin pyocyanin triggers,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9835,PHI:7391,UniProt,D4I0P2,GenBank,CBA22840,,,CFPB1430,EAMY _3003,,,,,,PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9836,PHI:7392,UniProt,D4I0P3,GenBank,CBA22843,,,CFPB1430,EAMY _3004,,,,,,PHI:7391; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9837,PHI:7393,UniProt,D4I0P4,GenBank,CBA22845,,,CFPB1430,EAMY _3005,,,,,,PHI:7391; PHI:7392; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9838,PHI:7394,UniProt,D4I0P5,GenBank,CBA22846,,,CFPB1430,EAMY _3006,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9839,PHI:7395,UniProt,D4I0P6,GenBank,CBA22848,,,CFPB1430,EAMY _3007,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9840,PHI:7396,UniProt,D4I0P7,GenBank,CBA22850,,,CFPB1430,EAMY _3008,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9841,PHI:7397,UniProt,D4I0P8,GenBank,CBA22852,,,CFPB1430,EAMY _3009,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9842,PHI:7398,UniProt,D4I0P9,GenBank,CBA22854,,,CFPB1430,EAMY _3010,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9843,PHI:7399,UniProt,D4I0Q0,GenBank,CBA22857,,,CFPB1430,EAMY _3011,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9844,PHI:7400,UniProt,D4I0Q1,GenBank,CBA22859,,,CFPB1430,EAMY _3012,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9845,PHI:7401,UniProt,D4I0Q2,GenBank,CBA22861,,,CFPB1430,EAMY _3013,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9846,PHI:7402,UniProt,D4I0Q3,GenBank,CBA22862,,,CFPB1430,EAMY _3014,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9847,PHI:7403,UniProt,D4I0Q4,GenBank,CBA22864,,,CFPB1430,EAMY _3015,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9848,PHI:7404,UniProt,D4I0Q5,GenBank,CBA22867,,,CFPB1430,EAMY _3016,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9849,PHI:7405,UniProt,D4I0Q6,GenBank,CBA22869,,,CFPB1430,EAMY _3017,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9850,PHI:7406,UniProt,D4I0Q7,GenBank,CBA22870,,,CFPB1430,EAMY _3018,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9851,PHI:7407,UniProt,D4I0Q8,GenBank,CBA22873,,,CFPB1430,EAMY _3019,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9852,PHI:7408,UniProt,D4I0Q9,GenBank,CBA22875,,,CFPB1430,EAMY _3020,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9853,PHI:7409,UniProt,D4I0R0,GenBank,CBA22876,,,CFPB1430,EAMY _3021,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9854,PHI:7410,UniProt,D4I0R1,GenBank,CBA22879,,,CFPB1430,EAMY _3022,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9855,PHI:7411,UniProt,D4I0R2,GenBank,CBA22880,,,CFPB1430,EAMY _3023,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9856,PHI:7412,UniProt,D4I0R3,GenBank,CBA22883,,,CFPB1430,EAMY _3024,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9857,PHI:7413,UniProt,D4I0R4,GenBank,CBA22885,,,CFPB1430,EAMY _3025,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9858,PHI:7414,UniProt,D4I0R5,GenBank,CBA22887,,,CFPB1430,EAMY _3026,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9859,PHI:7415,UniProt,D4I0R6,GenBank,CBA22889,,,CFPB1430,EAMY _3027,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9860,PHI:7416,UniProt,D4I0R7,GenBank,CBA22891,,,CFPB1430,EAMY _3028,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9861,PHI:7417,UniProt,D4I208,GenBank,CBA23229,,,CFPB1430,EAMY _3201,,,,,,PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9862,PHI:7418,UniProt,D4I209,GenBank,CBA23231,,,CFPB1430,EAMY _3202,,,,,,PHI:7417; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9863,PHI:7419,UniProt,D4I210,GenBank,CBA23233,,,CFPB1430,EAMY _3203,,,,,,PHI:7417; PHI:7418; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9864,PHI:7420,UniProt,D4I211,GenBank,CBA23236,,,CFPB1430,EAMY _3204,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9865,PHI:7421,UniProt,D4I212,GenBank,CBA23238,,,CFPB1430,EAMY _3205,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9866,PHI:7422,UniProt,D4I213,GenBank,CBA23240,,,CFPB1430,EAMY _3206,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9867,PHI:7423,UniProt,D4I214,GenBank,CBA23241,,,CFPB1430,EAMY _3207,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9868,PHI:7424,UniProt,D4I215,GenBank,CBA23243,,,CFPB1430,EAMY _3208,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9869,PHI:7425,UniProt,D4I216,GenBank,CBA23246,,,CFPB1430,EAMY _3209,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9870,PHI:7426,UniProt,D4I217,GenBank,CBA23248,,,CFPB1430,EAMY _3210,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9871,PHI:7427,UniProt,D4I218,GenBank,CBA23250,,,CFPB1430,EAMY _3211,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9872,PHI:7428,UniProt,D4I219,GenBank,CBA23251,,,CFPB1430,EAMY _3212,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9873,PHI:7429,UniProt,D4I220,GenBank,CBA23253,,,CFPB1430,EAMY _3213,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9874,PHI:7430,UniProt,D4I221,GenBank,CBA23255,,,CFPB1430,EAMY _3214,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9875,PHI:7431,UniProt,D4I222,GenBank,CBA23258,,,CFPB1430,EAMY _3215,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9876,PHI:7432,UniProt,D4I223,GenBank,CBA23260,,,CFPB1430,EAMY _3216,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9877,PHI:7433,UniProt,D4I224,GenBank,CBA23261,,,CFPB1430,EAMY _3217,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9878,PHI:7434,UniProt,D4I225,GenBank,CBA23263,,,CFPB1430,EAMY _3218,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9879,PHI:7435,UniProt,D4I226,GenBank,CBA23265,,,CFPB1430,EAMY _3219,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9880,PHI:7436,UniProt,D4I227,GenBank,CBA23268,,,CFPB1430,EAMY _3220,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9881,PHI:7437,UniProt,D4I228,GenBank,CBA23270,,,CFPB1430,EAMY _3221,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9882,PHI:7438,UniProt,D4I229,GenBank,CBA23271,,,CFPB1430,EAMY _3222,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9883,PHI:7439,UniProt,D4I230,GenBank,CBA23273,,,CFPB1430,EAMY _3223,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9884,PHI:7440,UniProt,D4I231,GenBank,CBA23275,,,CFPB1430,EAMY _3224,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9885,PHI:7441,UniProt,D4I232,GenBank,CBA23277,,,CFPB1430,EAMY _3225,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9886,PHI:7442,UniProt,D4I233,GenBank,CBA23279,,,CFPB1430,EAMY _3226,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9887,PHI:7443,UniProt,D4I234,GenBank,CBA23281,,,CFPB1430,EAMY _3227,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9888,PHI:7444,UniProt,D4I235,GenBank,CBA23284,,,CFPB1430,EAMY _3228,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9889,PHI:7391,UniProt,D4I0P2,GenBank,CBA22840,,,CFPB1430,EAMY _3003,,,,,,PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9890,PHI:7392,UniProt,D4I0P3,GenBank,CBA22843,,,CFPB1430,EAMY _3004,,,,,,PHI:7391; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9891,PHI:7393,UniProt,D4I0P4,GenBank,CBA22845,,,CFPB1430,EAMY _3005,,,,,,PHI:7391; PHI:7392; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9892,PHI:7394,UniProt,D4I0P5,GenBank,CBA22846,,,CFPB1430,EAMY _3006,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9893,PHI:7395,UniProt,D4I0P6,GenBank,CBA22848,,,CFPB1430,EAMY _3007,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9894,PHI:7396,UniProt,D4I0P7,GenBank,CBA22850,,,CFPB1430,EAMY _3008,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9895,PHI:7397,UniProt,D4I0P8,GenBank,CBA22852,,,CFPB1430,EAMY _3009,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9896,PHI:7398,UniProt,D4I0P9,GenBank,CBA22854,,,CFPB1430,EAMY _3010,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9897,PHI:7399,UniProt,D4I0Q0,GenBank,CBA22857,,,CFPB1430,EAMY _3011,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9898,PHI:7400,UniProt,D4I0Q1,GenBank,CBA22859,,,CFPB1430,EAMY _3012,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9899,PHI:7401,UniProt,D4I0Q2,GenBank,CBA22861,,,CFPB1430,EAMY _3013,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9900,PHI:7402,UniProt,D4I0Q3,GenBank,CBA22862,,,CFPB1430,EAMY _3014,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9901,PHI:7403,UniProt,D4I0Q4,GenBank,CBA22864,,,CFPB1430,EAMY _3015,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9902,PHI:7404,UniProt,D4I0Q5,GenBank,CBA22867,,,CFPB1430,EAMY _3016,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9903,PHI:7405,UniProt,D4I0Q6,GenBank,CBA22869,,,CFPB1430,EAMY _3017,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9904,PHI:7406,UniProt,D4I0Q7,GenBank,CBA22870,,,CFPB1430,EAMY _3018,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9905,PHI:7407,UniProt,D4I0Q8,GenBank,CBA22873,,,CFPB1430,EAMY _3019,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9906,PHI:7408,UniProt,D4I0Q9,GenBank,CBA22875,,,CFPB1430,EAMY _3020,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9907,PHI:7409,UniProt,D4I0R0,GenBank,CBA22876,,,CFPB1430,EAMY _3021,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9908,PHI:7410,UniProt,D4I0R1,GenBank,CBA22879,,,CFPB1430,EAMY _3022,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9909,PHI:7411,UniProt,D4I0R2,GenBank,CBA22880,,,CFPB1430,EAMY _3023,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9910,PHI:7412,UniProt,D4I0R3,GenBank,CBA22883,,,CFPB1430,EAMY _3024,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9911,PHI:7413,UniProt,D4I0R4,GenBank,CBA22885,,,CFPB1430,EAMY _3025,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9912,PHI:7414,UniProt,D4I0R5,GenBank,CBA22887,,,CFPB1430,EAMY _3026,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9913,PHI:7415,UniProt,D4I0R6,GenBank,CBA22889,,,CFPB1430,EAMY _3027,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9914,PHI:7416,UniProt,D4I0R7,GenBank,CBA22891,,,CFPB1430,EAMY _3028,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9915,PHI:7417,UniProt,D4I208,GenBank,CBA23229,,,CFPB1430,EAMY _3201,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9916,PHI:7418,UniProt,D4I209,GenBank,CBA23231,,,CFPB1430,EAMY _3202,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9917,PHI:7419,UniProt,D4I210,GenBank,CBA23233,,,CFPB1430,EAMY _3203,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9918,PHI:7420,UniProt,D4I211,GenBank,CBA23236,,,CFPB1430,EAMY _3204,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9919,PHI:7421,UniProt,D4I212,GenBank,CBA23238,,,CFPB1430,EAMY _3205,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9920,PHI:7422,UniProt,D4I213,GenBank,CBA23240,,,CFPB1430,EAMY _3206,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9921,PHI:7423,UniProt,D4I214,GenBank,CBA23241,,,CFPB1430,EAMY _3207,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9922,PHI:7424,UniProt,D4I215,GenBank,CBA23243,,,CFPB1430,EAMY _3208,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9923,PHI:7425,UniProt,D4I216,GenBank,CBA23246,,,CFPB1430,EAMY _3209,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9924,PHI:7426,UniProt,D4I217,GenBank,CBA23248,,,CFPB1430,EAMY _3210,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9925,PHI:7427,UniProt,D4I218,GenBank,CBA23250,,,CFPB1430,EAMY _3211,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9926,PHI:7428,UniProt,D4I219,GenBank,CBA23251,,,CFPB1430,EAMY _3212,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9927,PHI:7429,UniProt,D4I220,GenBank,CBA23253,,,CFPB1430,EAMY _3213,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9928,PHI:7430,UniProt,D4I221,GenBank,CBA23255,,,CFPB1430,EAMY _3214,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9929,PHI:7431,UniProt,D4I222,GenBank,CBA23258,,,CFPB1430,EAMY _3215,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9930,PHI:7432,UniProt,D4I223,GenBank,CBA23260,,,CFPB1430,EAMY _3216,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9931,PHI:7433,UniProt,D4I224,GenBank,CBA23261,,,CFPB1430,EAMY _3217,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9932,PHI:7434,UniProt,D4I225,GenBank,CBA23263,,,CFPB1430,EAMY _3218,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9933,PHI:7435,UniProt,D4I226,GenBank,CBA23265,,,CFPB1430,EAMY _3219,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9934,PHI:7436,UniProt,D4I227,GenBank,CBA23268,,,CFPB1430,EAMY _3220,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9935,PHI:7437,UniProt,D4I228,GenBank,CBA23270,,,CFPB1430,EAMY _3221,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9936,PHI:7438,UniProt,D4I229,GenBank,CBA23271,,,CFPB1430,EAMY _3222,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9937,PHI:7439,UniProt,D4I230,GenBank,CBA23273,,,CFPB1430,EAMY _3223,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9938,PHI:7440,UniProt,D4I231,GenBank,CBA23275,,,CFPB1430,EAMY _3224,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9939,PHI:7441,UniProt,D4I232,GenBank,CBA23277,,,CFPB1430,EAMY _3225,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9940,PHI:7442,UniProt,D4I233,GenBank,CBA23279,,,CFPB1430,EAMY _3226,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9941,PHI:7443,UniProt,D4I234,GenBank,CBA23281,,,CFPB1430,EAMY _3227,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9942,PHI:7444,UniProt,D4I235,GenBank,CBA23284,,,CFPB1430,EAMY _3228,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Conférence,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9943,PHI:7391,UniProt,D4I0P2,GenBank,CBA22840,,,CFPB1430,EAMY _3003,,,,,,PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9944,PHI:7392,UniProt,D4I0P3,GenBank,CBA22843,,,CFPB1430,EAMY _3004,,,,,,PHI:7391; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9945,PHI:7393,UniProt,D4I0P4,GenBank,CBA22845,,,CFPB1430,EAMY _3005,,,,,,PHI:7391; PHI:7392; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9946,PHI:7394,UniProt,D4I0P5,GenBank,CBA22846,,,CFPB1430,EAMY _3006,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9947,PHI:7395,UniProt,D4I0P6,GenBank,CBA22848,,,CFPB1430,EAMY _3007,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9948,PHI:7396,UniProt,D4I0P7,GenBank,CBA22850,,,CFPB1430,EAMY _3008,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9949,PHI:7397,UniProt,D4I0P8,GenBank,CBA22852,,,CFPB1430,EAMY _3009,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9950,PHI:7398,UniProt,D4I0P9,GenBank,CBA22854,,,CFPB1430,EAMY _3010,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9951,PHI:7399,UniProt,D4I0Q0,GenBank,CBA22857,,,CFPB1430,EAMY _3011,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9952,PHI:7400,UniProt,D4I0Q1,GenBank,CBA22859,,,CFPB1430,EAMY _3012,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9953,PHI:7401,UniProt,D4I0Q2,GenBank,CBA22861,,,CFPB1430,EAMY _3013,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9954,PHI:7402,UniProt,D4I0Q3,GenBank,CBA22862,,,CFPB1430,EAMY _3014,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9955,PHI:7403,UniProt,D4I0Q4,GenBank,CBA22864,,,CFPB1430,EAMY _3015,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9956,PHI:7404,UniProt,D4I0Q5,GenBank,CBA22867,,,CFPB1430,EAMY _3016,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9957,PHI:7405,UniProt,D4I0Q6,GenBank,CBA22869,,,CFPB1430,EAMY _3017,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9958,PHI:7406,UniProt,D4I0Q7,GenBank,CBA22870,,,CFPB1430,EAMY _3018,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9959,PHI:7407,UniProt,D4I0Q8,GenBank,CBA22873,,,CFPB1430,EAMY _3019,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9960,PHI:7408,UniProt,D4I0Q9,GenBank,CBA22875,,,CFPB1430,EAMY _3020,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9961,PHI:7409,UniProt,D4I0R0,GenBank,CBA22876,,,CFPB1430,EAMY _3021,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9962,PHI:7410,UniProt,D4I0R1,GenBank,CBA22879,,,CFPB1430,EAMY _3022,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9963,PHI:7411,UniProt,D4I0R2,GenBank,CBA22880,,,CFPB1430,EAMY _3023,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9964,PHI:7412,UniProt,D4I0R3,GenBank,CBA22883,,,CFPB1430,EAMY _3024,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9965,PHI:7413,UniProt,D4I0R4,GenBank,CBA22885,,,CFPB1430,EAMY _3025,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9966,PHI:7414,UniProt,D4I0R5,GenBank,CBA22887,,,CFPB1430,EAMY _3026,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9967,PHI:7415,UniProt,D4I0R6,GenBank,CBA22889,,,CFPB1430,EAMY _3027,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9968,PHI:7416,UniProt,D4I0R7,GenBank,CBA22891,,,CFPB1430,EAMY _3028,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9969,PHI:7417,UniProt,D4I208,GenBank,CBA23229,,,CFPB1430,EAMY _3201,,,,,,PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9970,PHI:7418,UniProt,D4I209,GenBank,CBA23231,,,CFPB1430,EAMY _3202,,,,,,PHI:7417; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9971,PHI:7419,UniProt,D4I210,GenBank,CBA23233,,,CFPB1430,EAMY _3203,,,,,,PHI:7417; PHI:7418; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9972,PHI:7420,UniProt,D4I211,GenBank,CBA23236,,,CFPB1430,EAMY _3204,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9973,PHI:7421,UniProt,D4I212,GenBank,CBA23238,,,CFPB1430,EAMY _3205,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9974,PHI:7422,UniProt,D4I213,GenBank,CBA23240,,,CFPB1430,EAMY _3206,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9975,PHI:7423,UniProt,D4I214,GenBank,CBA23241,,,CFPB1430,EAMY _3207,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9976,PHI:7424,UniProt,D4I215,GenBank,CBA23243,,,CFPB1430,EAMY _3208,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9977,PHI:7425,UniProt,D4I216,GenBank,CBA23246,,,CFPB1430,EAMY _3209,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9978,PHI:7426,UniProt,D4I217,GenBank,CBA23248,,,CFPB1430,EAMY _3210,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9979,PHI:7427,UniProt,D4I218,GenBank,CBA23250,,,CFPB1430,EAMY _3211,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9980,PHI:7428,UniProt,D4I219,GenBank,CBA23251,,,CFPB1430,EAMY _3212,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9981,PHI:7429,UniProt,D4I220,GenBank,CBA23253,,,CFPB1430,EAMY _3213,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9982,PHI:7430,UniProt,D4I221,GenBank,CBA23255,,,CFPB1430,EAMY _3214,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9983,PHI:7431,UniProt,D4I222,GenBank,CBA23258,,,CFPB1430,EAMY _3215,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9984,PHI:7432,UniProt,D4I223,GenBank,CBA23260,,,CFPB1430,EAMY _3216,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9985,PHI:7433,UniProt,D4I224,GenBank,CBA23261,,,CFPB1430,EAMY _3217,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9986,PHI:7434,UniProt,D4I225,GenBank,CBA23263,,,CFPB1430,EAMY _3218,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9987,PHI:7435,UniProt,D4I226,GenBank,CBA23265,,,CFPB1430,EAMY _3219,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9988,PHI:7436,UniProt,D4I227,GenBank,CBA23268,,,CFPB1430,EAMY _3220,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9989,PHI:7437,UniProt,D4I228,GenBank,CBA23270,,,CFPB1430,EAMY _3221,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9990,PHI:7438,UniProt,D4I229,GenBank,CBA23271,,,CFPB1430,EAMY _3222,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9991,PHI:7439,UniProt,D4I230,GenBank,CBA23273,,,CFPB1430,EAMY _3223,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9992,PHI:7440,UniProt,D4I231,GenBank,CBA23275,,,CFPB1430,EAMY _3224,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9993,PHI:7441,UniProt,D4I232,GenBank,CBA23277,,,CFPB1430,EAMY _3225,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9994,PHI:7442,UniProt,D4I233,GenBank,CBA23279,,,CFPB1430,EAMY _3226,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9995,PHI:7443,UniProt,D4I234,GenBank,CBA23281,,,CFPB1430,EAMY _3227,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9996,PHI:7444,UniProt,D4I235,GenBank,CBA23284,,,CFPB1430,EAMY _3228,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9997,PHI:7391,UniProt,D4I0P2,GenBank,CBA22840,,,CFPB1430,EAMY _3003,,,,,,PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9998,PHI:7392,UniProt,D4I0P3,GenBank,CBA22843,,,CFPB1430,EAMY _3004,,,,,,PHI:7391; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 9999,PHI:7393,UniProt,D4I0P4,GenBank,CBA22845,,,CFPB1430,EAMY _3005,,,,,,PHI:7391; PHI:7392; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10000,PHI:7394,UniProt,D4I0P5,GenBank,CBA22846,,,CFPB1430,EAMY _3006,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10001,PHI:7395,UniProt,D4I0P6,GenBank,CBA22848,,,CFPB1430,EAMY _3007,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10002,PHI:7396,UniProt,D4I0P7,GenBank,CBA22850,,,CFPB1430,EAMY _3008,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10003,PHI:7397,UniProt,D4I0P8,GenBank,CBA22852,,,CFPB1430,EAMY _3009,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10004,PHI:7398,UniProt,D4I0P9,GenBank,CBA22854,,,CFPB1430,EAMY _3010,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10005,PHI:7399,UniProt,D4I0Q0,GenBank,CBA22857,,,CFPB1430,EAMY _3011,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10006,PHI:7400,UniProt,D4I0Q1,GenBank,CBA22859,,,CFPB1430,EAMY _3012,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10007,PHI:7401,UniProt,D4I0Q2,GenBank,CBA22861,,,CFPB1430,EAMY _3013,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10008,PHI:7402,UniProt,D4I0Q3,GenBank,CBA22862,,,CFPB1430,EAMY _3014,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10009,PHI:7403,UniProt,D4I0Q4,GenBank,CBA22864,,,CFPB1430,EAMY _3015,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10010,PHI:7404,UniProt,D4I0Q5,GenBank,CBA22867,,,CFPB1430,EAMY _3016,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10011,PHI:7405,UniProt,D4I0Q6,GenBank,CBA22869,,,CFPB1430,EAMY _3017,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10012,PHI:7406,UniProt,D4I0Q7,GenBank,CBA22870,,,CFPB1430,EAMY _3018,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10013,PHI:7407,UniProt,D4I0Q8,GenBank,CBA22873,,,CFPB1430,EAMY _3019,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10014,PHI:7408,UniProt,D4I0Q9,GenBank,CBA22875,,,CFPB1430,EAMY _3020,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10015,PHI:7409,UniProt,D4I0R0,GenBank,CBA22876,,,CFPB1430,EAMY _3021,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10016,PHI:7410,UniProt,D4I0R1,GenBank,CBA22879,,,CFPB1430,EAMY _3022,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10017,PHI:7411,UniProt,D4I0R2,GenBank,CBA22880,,,CFPB1430,EAMY _3023,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10018,PHI:7412,UniProt,D4I0R3,GenBank,CBA22883,,,CFPB1430,EAMY _3024,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10019,PHI:7413,UniProt,D4I0R4,GenBank,CBA22885,,,CFPB1430,EAMY _3025,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10020,PHI:7414,UniProt,D4I0R5,GenBank,CBA22887,,,CFPB1430,EAMY _3026,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10021,PHI:7415,UniProt,D4I0R6,GenBank,CBA22889,,,CFPB1430,EAMY _3027,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10022,PHI:7416,UniProt,D4I0R7,GenBank,CBA22891,,,CFPB1430,EAMY _3028,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10023,PHI:7417,UniProt,D4I208,GenBank,CBA23229,,,CFPB1430,EAMY _3201,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10024,PHI:7418,UniProt,D4I209,GenBank,CBA23231,,,CFPB1430,EAMY _3202,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10025,PHI:7419,UniProt,D4I210,GenBank,CBA23233,,,CFPB1430,EAMY _3203,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10026,PHI:7420,UniProt,D4I211,GenBank,CBA23236,,,CFPB1430,EAMY _3204,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10027,PHI:7421,UniProt,D4I212,GenBank,CBA23238,,,CFPB1430,EAMY _3205,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10028,PHI:7422,UniProt,D4I213,GenBank,CBA23240,,,CFPB1430,EAMY _3206,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10029,PHI:7423,UniProt,D4I214,GenBank,CBA23241,,,CFPB1430,EAMY _3207,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10030,PHI:7424,UniProt,D4I215,GenBank,CBA23243,,,CFPB1430,EAMY _3208,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10031,PHI:7425,UniProt,D4I216,GenBank,CBA23246,,,CFPB1430,EAMY _3209,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10032,PHI:7426,UniProt,D4I217,GenBank,CBA23248,,,CFPB1430,EAMY _3210,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10033,PHI:7427,UniProt,D4I218,GenBank,CBA23250,,,CFPB1430,EAMY _3211,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10034,PHI:7428,UniProt,D4I219,GenBank,CBA23251,,,CFPB1430,EAMY _3212,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10035,PHI:7429,UniProt,D4I220,GenBank,CBA23253,,,CFPB1430,EAMY _3213,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10036,PHI:7430,UniProt,D4I221,GenBank,CBA23255,,,CFPB1430,EAMY _3214,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10037,PHI:7431,UniProt,D4I222,GenBank,CBA23258,,,CFPB1430,EAMY _3215,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10038,PHI:7432,UniProt,D4I223,GenBank,CBA23260,,,CFPB1430,EAMY _3216,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10039,PHI:7433,UniProt,D4I224,GenBank,CBA23261,,,CFPB1430,EAMY _3217,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10040,PHI:7434,UniProt,D4I225,GenBank,CBA23263,,,CFPB1430,EAMY _3218,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10041,PHI:7435,UniProt,D4I226,GenBank,CBA23265,,,CFPB1430,EAMY _3219,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10042,PHI:7436,UniProt,D4I227,GenBank,CBA23268,,,CFPB1430,EAMY _3220,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10043,PHI:7437,UniProt,D4I228,GenBank,CBA23270,,,CFPB1430,EAMY _3221,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10044,PHI:7438,UniProt,D4I229,GenBank,CBA23271,,,CFPB1430,EAMY _3222,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10045,PHI:7439,UniProt,D4I230,GenBank,CBA23273,,,CFPB1430,EAMY _3223,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,"putative type VI secretion system, effector protein",,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10046,PHI:7440,UniProt,D4I231,GenBank,CBA23275,,,CFPB1430,EAMY _3224,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10047,PHI:7441,UniProt,D4I232,GenBank,CBA23277,,,CFPB1430,EAMY _3225,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10048,PHI:7442,UniProt,D4I233,GenBank,CBA23279,,,CFPB1430,EAMY _3226,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10049,PHI:7443,UniProt,D4I234,GenBank,CBA23281,,,CFPB1430,EAMY _3227,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10050,PHI:7444,UniProt,D4I235,GenBank,CBA23284,,,CFPB1430,EAMY _3228,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,shoot,type VI secretion system protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10051,PHI:7391,UniProt,D4I0P2,GenBank,CBA22840,,,CFPB1430,EAMY _3003,,,,,,PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10052,PHI:7392,UniProt,D4I0P3,GenBank,CBA22843,,,CFPB1430,EAMY _3004,,,,,,PHI:7391; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10053,PHI:7393,UniProt,D4I0P4,GenBank,CBA22845,,,CFPB1430,EAMY _3005,,,,,,PHI:7391; PHI:7392; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10054,PHI:7394,UniProt,D4I0P5,GenBank,CBA22846,,,CFPB1430,EAMY _3006,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10055,PHI:7395,UniProt,D4I0P6,GenBank,CBA22848,,,CFPB1430,EAMY _3007,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10056,PHI:7396,UniProt,D4I0P7,GenBank,CBA22850,,,CFPB1430,EAMY _3008,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10057,PHI:7397,UniProt,D4I0P8,GenBank,CBA22852,,,CFPB1430,EAMY _3009,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10058,PHI:7398,UniProt,D4I0P9,GenBank,CBA22854,,,CFPB1430,EAMY _3010,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10059,PHI:7399,UniProt,D4I0Q0,GenBank,CBA22857,,,CFPB1430,EAMY _3011,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10060,PHI:7400,UniProt,D4I0Q1,GenBank,CBA22859,,,CFPB1430,EAMY _3012,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10061,PHI:7401,UniProt,D4I0Q2,GenBank,CBA22861,,,CFPB1430,EAMY _3013,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10062,PHI:7402,UniProt,D4I0Q3,GenBank,CBA22862,,,CFPB1430,EAMY _3014,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10063,PHI:7403,UniProt,D4I0Q4,GenBank,CBA22864,,,CFPB1430,EAMY _3015,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10064,PHI:7404,UniProt,D4I0Q5,GenBank,CBA22867,,,CFPB1430,EAMY _3016,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10065,PHI:7405,UniProt,D4I0Q6,GenBank,CBA22869,,,CFPB1430,EAMY _3017,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10066,PHI:7406,UniProt,D4I0Q7,GenBank,CBA22870,,,CFPB1430,EAMY _3018,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10067,PHI:7407,UniProt,D4I0Q8,GenBank,CBA22873,,,CFPB1430,EAMY _3019,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10068,PHI:7408,UniProt,D4I0Q9,GenBank,CBA22875,,,CFPB1430,EAMY _3020,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10069,PHI:7409,UniProt,D4I0R0,GenBank,CBA22876,,,CFPB1430,EAMY _3021,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10070,PHI:7410,UniProt,D4I0R1,GenBank,CBA22879,,,CFPB1430,EAMY _3022,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10071,PHI:7411,UniProt,D4I0R2,GenBank,CBA22880,,,CFPB1430,EAMY _3023,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10072,PHI:7412,UniProt,D4I0R3,GenBank,CBA22883,,,CFPB1430,EAMY _3024,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7413; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10073,PHI:7413,UniProt,D4I0R4,GenBank,CBA22885,,,CFPB1430,EAMY _3025,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7414; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10074,PHI:7414,UniProt,D4I0R5,GenBank,CBA22887,,,CFPB1430,EAMY _3026,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7415; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10075,PHI:7415,UniProt,D4I0R6,GenBank,CBA22889,,,CFPB1430,EAMY _3027,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7416,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10076,PHI:7416,UniProt,D4I0R7,GenBank,CBA22891,,,CFPB1430,EAMY _3028,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10077,PHI:7417,UniProt,D4I208,GenBank,CBA23229,,,CFPB1430,EAMY _3201,,,,,,PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10078,PHI:7418,UniProt,D4I209,GenBank,CBA23231,,,CFPB1430,EAMY _3202,,,,,,PHI:7417; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10079,PHI:7419,UniProt,D4I210,GenBank,CBA23233,,,CFPB1430,EAMY _3203,,,,,,PHI:7417; PHI:7418; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10080,PHI:7420,UniProt,D4I211,GenBank,CBA23236,,,CFPB1430,EAMY _3204,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10081,PHI:7421,UniProt,D4I212,GenBank,CBA23238,,,CFPB1430,EAMY _3205,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10082,PHI:7422,UniProt,D4I213,GenBank,CBA23240,,,CFPB1430,EAMY _3206,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10083,PHI:7423,UniProt,D4I214,GenBank,CBA23241,,,CFPB1430,EAMY _3207,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10084,PHI:7424,UniProt,D4I215,GenBank,CBA23243,,,CFPB1430,EAMY _3208,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10085,PHI:7425,UniProt,D4I216,GenBank,CBA23246,,,CFPB1430,EAMY _3209,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10086,PHI:7426,UniProt,D4I217,GenBank,CBA23248,,,CFPB1430,EAMY _3210,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10087,PHI:7427,UniProt,D4I218,GenBank,CBA23250,,,CFPB1430,EAMY _3211,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10088,PHI:7428,UniProt,D4I219,GenBank,CBA23251,,,CFPB1430,EAMY _3212,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10089,PHI:7429,UniProt,D4I220,GenBank,CBA23253,,,CFPB1430,EAMY _3213,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10090,PHI:7430,UniProt,D4I221,GenBank,CBA23255,,,CFPB1430,EAMY _3214,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10091,PHI:7431,UniProt,D4I222,GenBank,CBA23258,,,CFPB1430,EAMY _3215,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10092,PHI:7432,UniProt,D4I223,GenBank,CBA23260,,,CFPB1430,EAMY _3216,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10093,PHI:7433,UniProt,D4I224,GenBank,CBA23261,,,CFPB1430,EAMY _3217,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10094,PHI:7434,UniProt,D4I225,GenBank,CBA23263,,,CFPB1430,EAMY _3218,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10095,PHI:7435,UniProt,D4I226,GenBank,CBA23265,,,CFPB1430,EAMY _3219,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10096,PHI:7436,UniProt,D4I227,GenBank,CBA23268,,,CFPB1430,EAMY _3220,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10097,PHI:7437,UniProt,D4I228,GenBank,CBA23270,,,CFPB1430,EAMY _3221,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10098,PHI:7438,UniProt,D4I229,GenBank,CBA23271,,,CFPB1430,EAMY _3222,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10099,PHI:7439,UniProt,D4I230,GenBank,CBA23273,,,CFPB1430,EAMY _3223,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10100,PHI:7440,UniProt,D4I231,GenBank,CBA23275,,,CFPB1430,EAMY _3224,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10101,PHI:7441,UniProt,D4I232,GenBank,CBA23277,,,CFPB1430,EAMY _3225,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10102,PHI:7442,UniProt,D4I233,GenBank,CBA23279,,,CFPB1430,EAMY _3226,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10103,PHI:7443,UniProt,D4I234,GenBank,CBA23281,,,CFPB1430,EAMY _3227,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10104,PHI:7444,UniProt,D4I235,GenBank,CBA23284,,,CFPB1430,EAMY _3228,,,,,,PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10105,PHI:7391,UniProt,D4I0P2,GenBank,CBA22840,,,CFPB1430,EAMY _3003,,,,,,PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10106,PHI:7392,UniProt,D4I0P3,GenBank,CBA22843,,,CFPB1430,EAMY _3004,,,,,,PHI:7391; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10107,PHI:7393,UniProt,D4I0P4,GenBank,CBA22845,,,CFPB1430,EAMY _3005,,,,,,PHI:7391; PHI:7392; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10108,PHI:7394,UniProt,D4I0P5,GenBank,CBA22846,,,CFPB1430,EAMY _3006,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10109,PHI:7395,UniProt,D4I0P6,GenBank,CBA22848,,,CFPB1430,EAMY _3007,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10110,PHI:7396,UniProt,D4I0P7,GenBank,CBA22850,,,CFPB1430,EAMY _3008,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10111,PHI:7397,UniProt,D4I0P8,GenBank,CBA22852,,,CFPB1430,EAMY _3009,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10112,PHI:7398,UniProt,D4I0P9,GenBank,CBA22854,,,CFPB1430,EAMY _3010,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10113,PHI:7399,UniProt,D4I0Q0,GenBank,CBA22857,,,CFPB1430,EAMY _3011,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10114,PHI:7400,UniProt,D4I0Q1,GenBank,CBA22859,,,CFPB1430,EAMY _3012,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10115,PHI:7401,UniProt,D4I0Q2,GenBank,CBA22861,,,CFPB1430,EAMY _3013,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10116,PHI:7402,UniProt,D4I0Q3,GenBank,CBA22862,,,CFPB1430,EAMY _3014,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10117,PHI:7403,UniProt,D4I0Q4,GenBank,CBA22864,,,CFPB1430,EAMY _3015,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10118,PHI:7404,UniProt,D4I0Q5,GenBank,CBA22867,,,CFPB1430,EAMY _3016,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10119,PHI:7405,UniProt,D4I0Q6,GenBank,CBA22869,,,CFPB1430,EAMY _3017,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10120,PHI:7406,UniProt,D4I0Q7,GenBank,CBA22870,,,CFPB1430,EAMY _3018,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10121,PHI:7407,UniProt,D4I0Q8,GenBank,CBA22873,,,CFPB1430,EAMY _3019,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10122,PHI:7408,UniProt,D4I0Q9,GenBank,CBA22875,,,CFPB1430,EAMY _3020,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10123,PHI:7409,UniProt,D4I0R0,GenBank,CBA22876,,,CFPB1430,EAMY _3021,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10124,PHI:7410,UniProt,D4I0R1,GenBank,CBA22879,,,CFPB1430,EAMY _3022,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10125,PHI:7411,UniProt,D4I0R2,GenBank,CBA22880,,,CFPB1430,EAMY _3023,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10126,PHI:7412,UniProt,D4I0R3,GenBank,CBA22883,,,CFPB1430,EAMY _3024,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10127,PHI:7413,UniProt,D4I0R4,GenBank,CBA22885,,,CFPB1430,EAMY _3025,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10128,PHI:7414,UniProt,D4I0R5,GenBank,CBA22887,,,CFPB1430,EAMY _3026,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10129,PHI:7415,UniProt,D4I0R6,GenBank,CBA22889,,,CFPB1430,EAMY _3027,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10130,PHI:7416,UniProt,D4I0R7,GenBank,CBA22891,,,CFPB1430,EAMY _3028,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10131,PHI:7417,UniProt,D4I208,GenBank,CBA23229,,,CFPB1430,EAMY _3201,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10132,PHI:7418,UniProt,D4I209,GenBank,CBA23231,,,CFPB1430,EAMY _3202,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10133,PHI:7419,UniProt,D4I210,GenBank,CBA23233,,,CFPB1430,EAMY _3203,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10134,PHI:7420,UniProt,D4I211,GenBank,CBA23236,,,CFPB1430,EAMY _3204,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10135,PHI:7421,UniProt,D4I212,GenBank,CBA23238,,,CFPB1430,EAMY _3205,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10136,PHI:7422,UniProt,D4I213,GenBank,CBA23240,,,CFPB1430,EAMY _3206,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10137,PHI:7423,UniProt,D4I214,GenBank,CBA23241,,,CFPB1430,EAMY _3207,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10138,PHI:7424,UniProt,D4I215,GenBank,CBA23243,,,CFPB1430,EAMY _3208,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10139,PHI:7425,UniProt,D4I216,GenBank,CBA23246,,,CFPB1430,EAMY _3209,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10140,PHI:7426,UniProt,D4I217,GenBank,CBA23248,,,CFPB1430,EAMY _3210,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10141,PHI:7427,UniProt,D4I218,GenBank,CBA23250,,,CFPB1430,EAMY _3211,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10142,PHI:7428,UniProt,D4I219,GenBank,CBA23251,,,CFPB1430,EAMY _3212,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10143,PHI:7429,UniProt,D4I220,GenBank,CBA23253,,,CFPB1430,EAMY _3213,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10144,PHI:7430,UniProt,D4I221,GenBank,CBA23255,,,CFPB1430,EAMY _3214,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10145,PHI:7431,UniProt,D4I222,GenBank,CBA23258,,,CFPB1430,EAMY _3215,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10146,PHI:7432,UniProt,D4I223,GenBank,CBA23260,,,CFPB1430,EAMY _3216,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10147,PHI:7433,UniProt,D4I224,GenBank,CBA23261,,,CFPB1430,EAMY _3217,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10148,PHI:7434,UniProt,D4I225,GenBank,CBA23263,,,CFPB1430,EAMY _3218,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10149,PHI:7435,UniProt,D4I226,GenBank,CBA23265,,,CFPB1430,EAMY _3219,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10150,PHI:7436,UniProt,D4I227,GenBank,CBA23268,,,CFPB1430,EAMY _3220,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10151,PHI:7437,UniProt,D4I228,GenBank,CBA23270,,,CFPB1430,EAMY _3221,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10152,PHI:7438,UniProt,D4I229,GenBank,CBA23271,,,CFPB1430,EAMY _3222,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10153,PHI:7439,UniProt,D4I230,GenBank,CBA23273,,,CFPB1430,EAMY _3223,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7440; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,"putative type VI secretion system, effector protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10154,PHI:7440,UniProt,D4I231,GenBank,CBA23275,,,CFPB1430,EAMY _3224,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7441; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10155,PHI:7441,UniProt,D4I232,GenBank,CBA23277,,,CFPB1430,EAMY _3225,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7442; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10156,PHI:7442,UniProt,D4I233,GenBank,CBA23279,,,CFPB1430,EAMY _3226,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7443; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10157,PHI:7443,UniProt,D4I234,GenBank,CBA23281,,,CFPB1430,EAMY _3227,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7444,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10158,PHI:7444,UniProt,D4I235,GenBank,CBA23284,,,CFPB1430,EAMY _3228,,,,,,PHI:7391; PHI:7392; PHI:7393; PHI:7394; PHI:7395; PHI:7396; PHI:7397; PHI:7398; PHI:7399; PHI:7400; PHI:7401; PHI:7402; PHI:7403; PHI:7404; PHI:7405; PHI:7406; PHI:7407; PHI:7408; PHI:7409; PHI:7410; PHI:7411; PHI:7412; PHI:7413; PHI:7414; PHI:7415; PHI:7416; PHI:7417; PHI:7418; PHI:7419; PHI:7420; PHI:7421; PHI:7422; PHI:7423; PHI:7424; PHI:7425; PHI:7426; PHI:7427; PHI:7428; PHI:7429; PHI:7430; PHI:7431; PHI:7432; PHI:7433; PHI:7434; PHI:7435; PHI:7436; PHI:7437; PHI:7438; PHI:7439; PHI:7440; PHI:7441; PHI:7442; PHI:7443,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,flower,type VI secretion system protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,28818038,PubMed,10.1186/s12864-017-4010-1,BMC Genomics.2017 Aug 17;18(1):628,theo.smits@zhaw.ch,"Plant assays showed that mutants in T6SS-3 were slightly more virulent in apple shoots while inducing less disease symptoms on apple flowers, indicating that T6SSs have only a minor effect on virulence of E. amylovora CFBP 1430.",T Kamber 2017,2017,54 genes,Kamber-2017-Role of the type VI secretion syst,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10159,PHI:7445,UniProt,F9X7W8,JGI,Mycgr3G70181,,,,Ssk1,JGI Chr.3 at position 2.499.750 / ID: 70181,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,two-component response regulator,,,HOG pathway,reduced virulence,,,,,,,,wild type,reduced,no,sorbitol; hydrogen peroxide; Congo red; sodium dodecyl sulfate (SDS); NaCl; fludioxonil,sorbitol: CHEBI:30911; H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; fludioxonil: CHEBI:81763,,,,,gene deletion: full; gene complementation,,,YVS,28829795,PubMed,10.1371/journal.pone.0183065,PLoS One.2017 Aug 22;12(8):e0183065,yemelin@ibwf.de,Mutant lacking MYCO4 gene exhibited adenine auxotrophy and mutant lacking ZtSSK1 was sensitive to oxidative and osmotic stress responses and showed fungicide resistance.,A Yemelin 2017,2017,2 genes,Yemelin-2017-Identification of factors involve,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10160,PHI:7446,UniProt,F9XHT2,JGI,Mycgr3G87000,,,,Myco4,JGI Chr.8 at position 84.634 / ID: 87000,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,phosphoribosylamine-glycine ligase,,,de novo purine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28829795,PubMed,10.1371/journal.pone.0183065,PLoS One.2017 Aug 22;12(8):e0183065,yemelin@ibwf.de,Mutant lacking MYCO4 gene exhibited adenine auxotrophy and mutant lacking ZtSSK1 was sensitive to oxidative and osmotic stress responses and showed fungicide resistance.,A Yemelin 2017,2017,2 genes,Yemelin-2017-Identification of factors involve,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10161,PHI:7447,UniProt,A0A1S6JYV9,GenBank,AQS95511,,,,CpSlt2,,,,,,,5116,Cryphonectria parasitica,660469,EP155/2,blight (chestnut),eudicots,21020,Castanea sativa (related: chestnut),,,,bark,MAP kinase,,,cell wall integrity signaling pathway,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,sorbitol; Congo red; sodium dodecyl sulfate (SDS); menadione,sorbitol: CHEBI:30911; Congo red: CHEBI:34653; SDS: CHEBI:8984; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,28831166,PubMed,10.1038/s41598-017-09383-y,Sci Rep.2017 Aug 22;7(1):9038,dhkim@jbnu.ac.kr,CpSlt2-null mutant exhibited CWI-related phenotypic defects including hypersensitivity to cell wall-disturbing agents and other stresses.,K K So 2017,2017,1 gene,So-2017-Mutation of the Slt2 ortholog from Cry,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10162,PHI:7448,UniProt,P52616,GenBank,AAC43354,,,SL 375,fljB,,fljB C1362G,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,peritoneum,flagellin,,,,increased virulence (hypervirulence),,,,,,,,,,,,,,,,,gene mutation,,,YVS,28874555,PubMed,10.1073/pnas.1705437114,Proc Natl Acad Sci U S A.2017 Sep 19;114(38):10232-10237,eunjinlee@khu.ac.kr,"The fljB nucleotide substitution renders Salmonella hypervirulent, indicating that FljB-based motility must be compromised in the phagosomal compartment where Salmonella resides.",E Choi 2017,2017,2 genes,Choi-2017-A trans-acting leader RNA from a Sal,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10163,PHI:7448,UniProt,P52616,GenBank,AAC43354,,,SL 375,fljB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,peritoneum,flagellin,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene mutation,,,YVS,28874555,PubMed,10.1073/pnas.1705437114,Proc Natl Acad Sci U S A.2017 Sep 19;114(38):10232-10237,eunjinlee@khu.ac.kr,"The fljB nucleotide substitution renders Salmonella hypervirulent, indicating that FljB-based motility must be compromised in the phagosomal compartment where Salmonella resides.",E Choi 2017,2017,2 genes,Choi-2017-A trans-acting leader RNA from a Sal,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10164,PHI:7449,UniProt,P06179,GenBank,AAA27072,,,,fliC,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,peritoneum,flagellin,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene mutation,,,YVS,28874555,PubMed,10.1073/pnas.1705437114,Proc Natl Acad Sci U S A.2017 Sep 19;114(38):10232-10237,eunjinlee@khu.ac.kr,"The fljB nucleotide substitution renders Salmonella hypervirulent, indicating that FljB-based motility must be compromised in the phagosomal compartment where Salmonella resides.",E Choi 2017,2017,2 genes,Choi-2017-A trans-acting leader RNA from a Sal,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10165,PHI:7448,UniProt,P52616,GenBank,AAC43354,,,SL 375,fljB,,,,,,PHI:7449,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,peritoneum,flagellin,,,,reduced virulence,,,,,,,,,,,,,,,,,gene mutation,,,YVS,28874555,PubMed,10.1073/pnas.1705437114,Proc Natl Acad Sci U S A.2017 Sep 19;114(38):10232-10237,eunjinlee@khu.ac.kr,"The fljB nucleotide substitution renders Salmonella hypervirulent, indicating that FljB-based motility must be compromised in the phagosomal compartment where Salmonella resides.",E Choi 2017,2017,2 genes,Choi-2017-A trans-acting leader RNA from a Sal,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10166,PHI:7449,UniProt,P06179,GenBank,AAA27072,,,,fliC,,,,,,PHI:7448,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,peritoneum,flagellin,,,,reduced virulence,,,,,,,,,,,,,,,,,gene mutation,,,YVS,28874555,PubMed,10.1073/pnas.1705437114,Proc Natl Acad Sci U S A.2017 Sep 19;114(38):10232-10237,eunjinlee@khu.ac.kr,"The fljB nucleotide substitution renders Salmonella hypervirulent, indicating that FljB-based motility must be compromised in the phagosomal compartment where Salmonella resides.",E Choi 2017,2017,2 genes,Choi-2017-A trans-acting leader RNA from a Sal,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10167,PHI:7450,UniProt,G0Z025,GenBank,AEI60186,,,B40,SElX,,,,,,,1280,Staphylococcus aureus,,JSNZ,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver; kidney,staphylococcal enterotoxin-like toxin X,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28880913,PubMed,10.1371/journal.ppat.1006549,PLoS Pathog.2017 Sep 7;13(9):e1006549,r.langley@auckland.ac.nz,"S. aureus carrying the glycan-binding site mutated selXgene, JSNZselXR141A was affected in the ability of SElX to bind to cells of myeloid origin and significantly reduced its ability to protect S. aureus from destruction in a whole blood killing (WBK) assay.",R J Langley 2017,2017,1 gene,Langley-2017-Staphylococcal enterotoxin-like X,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10168,PHI:7450,UniProt,G0Z025,GenBank,AEI60186,,,B40,SElX,,selXR141A,,,,,1280,Staphylococcus aureus,,JSNZ,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,staphylococcal enterotoxin-like toxin X,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28880913,PubMed,10.1371/journal.ppat.1006549,PLoS Pathog.2017 Sep 7;13(9):e1006549,r.langley@auckland.ac.nz,"S. aureus carrying the glycan-binding site mutated selXgene, JSNZselXR141A was affected in the ability of SElX to bind to cells of myeloid origin and significantly reduced its ability to protect S. aureus from destruction in a whole blood killing (WBK) assay.",R J Langley 2017,2017,1 gene,Langley-2017-Staphylococcal enterotoxin-like X,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10169,PHI:7451,UniProt,Q87Y52,GenBank,AAO57418,,,DC3000,PSPTO_3957,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,conserved hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28073812,PubMed,10.1093/femsle/fnx004,FEMS Microbiol Lett.2017 Apr 1;364(8),Melanie.filiatrault@ars.usda.gov,"PSPTO_3957 did not influence growth on rich media, motility or biofilm formation but was necessary for nitrate assimilation and full virulence in P. syringae.",K D'Amico 2017,2017,1 gene,D'Amico-2017-The conserved hypothetical protei,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10170,PHI:7452,UniProt,P9WI87,GenBank,CCP46132,,,H37Rv,MTP,,,,,,,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C3HeB/FeJ,,,spleen; lung,pilus,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27586540,PubMed,10.1099/mic.0.000368,Microbiology.2016 Oct;162(10):1784-1796,stallings@wusm.wustl.edu,"It was found that neither MTP nor the hypothetical Flp pilus was required for Mtb survival in mouse models of infection, although MTP can contribute to biofilm formation and subsequent isoniazid tolerance.",K M Mann 2016,2016,5 genes,Mann-2016-Analysis of the contribution of MTP,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10171,PHI:7452,UniProt,P9WI87,GenBank,CCP46132,,,H37Rv,MTP,,,,,,,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,pilus,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27586540,PubMed,10.1099/mic.0.000368,Microbiology.2016 Oct;162(10):1784-1796,stallings@wusm.wustl.edu,"It was found that neither MTP nor the hypothetical Flp pilus was required for Mtb survival in mouse models of infection, although MTP can contribute to biofilm formation and subsequent isoniazid tolerance.",K M Mann 2016,2016,5 genes,Mann-2016-Analysis of the contribution of MTP,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10172,PHI:7453,UniProt,P9WMT3,GenBank,CCP46482,,,H37Rv,TadA,,,,,,PHI:7454,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,inner membrane ATPase that drives pilin assembly,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27586540,PubMed,10.1099/mic.0.000368,Microbiology.2016 Oct;162(10):1784-1796,stallings@wusm.wustl.edu,"It was found that neither MTP nor the hypothetical Flp pilus was required for Mtb survival in mouse models of infection, although MTP can contribute to biofilm formation and subsequent isoniazid tolerance.",K M Mann 2016,2016,5 genes,Mann-2016-Analysis of the contribution of MTP,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10173,PHI:7454,UniProt,I6Y479,GenBank,CCP46481,,,H37Rv,TadB,,,,,,PHI:7453,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,secretion apparatus involved in pilin assembly,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27586540,PubMed,10.1099/mic.0.000368,Microbiology.2016 Oct;162(10):1784-1796,stallings@wusm.wustl.edu,"It was found that neither MTP nor the hypothetical Flp pilus was required for Mtb survival in mouse models of infection, although MTP can contribute to biofilm formation and subsequent isoniazid tolerance.",K M Mann 2016,2016,5 genes,Mann-2016-Analysis of the contribution of MTP,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10174,PHI:7455,UniProt,O69625,GenBank,CCP46480,,,H37Rv,TadC,,,,,,PHI:7456,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,secretion apparatus involved in pilin assembly,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27586540,PubMed,10.1099/mic.0.000368,Microbiology.2016 Oct;162(10):1784-1796,stallings@wusm.wustl.edu,"It was found that neither MTP nor the hypothetical Flp pilus was required for Mtb survival in mouse models of infection, although MTP can contribute to biofilm formation and subsequent isoniazid tolerance.",K M Mann 2016,2016,5 genes,Mann-2016-Analysis of the contribution of MTP,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10175,PHI:7456,UniProt,O69624,GenBank,CCP46479,,,H37Rv,flp,,,,,,PHI:7455,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung,major pilin structural unit,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27586540,PubMed,10.1099/mic.0.000368,Microbiology.2016 Oct;162(10):1784-1796,stallings@wusm.wustl.edu,"It was found that neither MTP nor the hypothetical Flp pilus was required for Mtb survival in mouse models of infection, although MTP can contribute to biofilm formation and subsequent isoniazid tolerance.",K M Mann 2016,2016,5 genes,Mann-2016-Analysis of the contribution of MTP,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10176,PHI:7457,UniProt,Q4WPS9,GenBank,EAL89755,,,Af293,RamA,chromosome 4,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,farnesyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,dithiothreitol; brefeldin A; bathophenanthroline disulfonic acid; cobalt chloride; hydrogen peroxide; nikkomycin Z; amphotericin B; voriconazole; itraconazole; caspofungin,dithiothreitol: CHEBI:42170; brefeldin A: CHEBI:48080; bathophenanthroline disulfonic acid: CHEBI:78159; cobalt chloride: CHEBI:35696; hydrogen peroxide: CHEBI:16240; nikkomycin Z: CHEBI:623918; amphotericin B: CHEBI:2682; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,28489963,PubMed,10.1080/21505594.2017.1328343,Virulence.2017 May 10:1-16,jfortwen@uthsc.edu,Loss of ramA reduced susceptibility to the antifungal drug voriconazole.,T S Norton 2017,2017,1 gene,Norton-2017-The Aspergillus fumigatus Farnesyl,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10177,PHI:7458,UniProt,Q8P877,GenBank,AAM41644,,,ATCC 33913,XCC2366,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain Xc17(pRK415),black rot,eudicots,3712,Brassica oleracea (no common name found),,,,leaf,TetR family transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,acriflavin,acriflavin: CHEBI:74728,,,,,gene deletion: full; gene complementation,,,YVS,28821943,PubMed,10.1007/s00284-017-1328-5,Curr Microbiol.2017 Aug 18,ymhsiao@ctust.edu.tw,XCC2366 is involved in the resistance to acriflavin and is necessary for virulence in Xcc.,C T Liao 2017,2017,1 gene,"Liao-2017-XCC2366, A Gene Encoding A Putative",BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10178,PHI:7461,UniProt,O87822,GenBank,CAA07190,,,GMI1000,hrpG,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root; leaf,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28840786,PubMed,10.1094/MPMI-05-17-0109-FI,Mol Plant Microbe Interact.2017 Aug 25,marcvalls@ub.edu,The capacity to colonize Arabidopsis plants of hrpB was significantly higher than of hrpG mutants.,H Lu 2017,2017,5 genes,Lu-2017-Type III secretion-dependent and -inde,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10179,PHI:7462,UniProt,P31778,GenBank,CAB58260,,,GMI1000,hrpB,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root; leaf,virulence regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28840786,PubMed,10.1094/MPMI-05-17-0109-FI,Mol Plant Microbe Interact.2017 Aug 25,marcvalls@ub.edu,The capacity to colonize Arabidopsis plants of hrpB was significantly higher than of hrpG mutants.,H Lu 2017,2017,5 genes,Lu-2017-Type III secretion-dependent and -inde,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10180,PHI:7463,UniProt,Q7ALD9,GenBank,CAD18029,,,GMI1000,prhA,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root; leaf,membrane receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28840786,PubMed,10.1094/MPMI-05-17-0109-FI,Mol Plant Microbe Interact.2017 Aug 25,marcvalls@ub.edu,The capacity to colonize Arabidopsis plants of hrpB was significantly higher than of hrpG mutants.,H Lu 2017,2017,5 genes,Lu-2017-Type III secretion-dependent and -inde,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10181,PHI:7464,UniProt,Q7ALF2,GenBank,CAD18000,,,GMI1000,prhI,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root; leaf,signal transducer,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28840786,PubMed,10.1094/MPMI-05-17-0109-FI,Mol Plant Microbe Interact.2017 Aug 25,marcvalls@ub.edu,The capacity to colonize Arabidopsis plants of hrpB was significantly higher than of hrpG mutants.,H Lu 2017,2017,5 genes,Lu-2017-Type III secretion-dependent and -inde,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10182,PHI:7465,UniProt,Q7ALF0,GenBank,CAD18002,,,GMI1000,prhJ,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,root; leaf,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28840786,PubMed,10.1094/MPMI-05-17-0109-FI,Mol Plant Microbe Interact.2017 Aug 25,marcvalls@ub.edu,The capacity to colonize Arabidopsis plants of hrpB was significantly higher than of hrpG mutants.,H Lu 2017,2017,5 genes,Lu-2017-Type III secretion-dependent and -inde,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10183,PHI:7466,UniProt,E8VX91,GenBank,ADV88279,,,MO6-24/O,VvPlpA,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneum; blood,putative phospholipase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28855258,PubMed,10.1074/jbc.M117.791657,J Biol Chem.2017 Aug 30. pii: jbc.M117.791657,bskim@kribb.re.kr,"PlpA mutation attenuated the release of actin and the cytosolic cyclophilin A from INT-407 cells, indicating that VvPlpA is a virulence factor essential for causing lysis and necrotic death of the epithelial cells.",K K Jang 2017,2017,1 gene,Jang-2017-Identification and characterization,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10184,PHI:7467,UniProt,A0A1B4Z8B0,GenBank,BAV55642,,,JMUB1235,shp,,,,,,,1314,Streptococcus pyogenes,293653,MGAS5005,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; spleen; liver; lung; kidney,streptococcal heme binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28830075,PubMed,10.1093/femspd/ftx085,Pathog Dis.2017 Sep 29;75(7),dzhuhui@aliyun.com,The growth of the Δshp mutant was significantly slower than MGAS5005 and Δshp-c than in non-immune human blood and in incubation with isolated rat neutrophils.,X Zhang 2017,2017,1 gene,Zhang-2017-Streptococcal heme binding protein,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10185,PHI:7467,UniProt,A0A1B4Z8B0,GenBank,BAV55642,,,JMUB1235,shp,,,,,,,1314,Streptococcus pyogenes,293653,MGAS5005,skin lesion,rodents,10117,Rattus rattus (related: black rat),,,,neutrophil,streptococcal heme binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28830075,PubMed,10.1093/femspd/ftx085,Pathog Dis.2017 Sep 29;75(7),dzhuhui@aliyun.com,The growth of the Δshp mutant was significantly slower than MGAS5005 and Δshp-c than in non-immune human blood and in incubation with isolated rat neutrophils.,X Zhang 2017,2017,1 gene,Zhang-2017-Streptococcal heme binding protein,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10186,PHI:7468,,no data found,GenBank,AAZ51319,,,MGAS5005,CpsY,,,,,,,1314,Streptococcus pyogenes,,5448,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin; peritoneum; blood,"surface-associated protein, virulence factor",,,,unaffected pathogenicity,,,,,,,,wild type,,no,carbenicillin; nisin; bacitracin,carbenicillin: CHEBI:3393; nisin: CHEBI:71629; bacitracin: CHEBI:28669,,,,,gene deletion: partial; gene complementation,,,YVS,27993974,PubMed,10.1128/IAI.00925-16,Infect Immun.2017 Feb 23;85(3). pii: e00925-16,kmciver@umd.edu,"CpsY is involved in GAS resistance to innate immune cells of its human host, the loss of CpsY in GAS does not result in virulence defects in murine models of infection, suggesting that CpsY function in immune evasion is specific to the human host.",L A Vega 2017,2017,1 gene,Vega-2017-The Transcriptional Regulator CpsY I,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10187,PHI:7468,,no data found,GenBank,AAZ51319,,,MGAS5005,CpsY,,,,,,,1314,Streptococcus pyogenes,,5448,infection,primates,9606,Homo sapiens (related: human),,,,polymorphonuclear leukocyte; monocyte,"surface-associated protein, virulence factor",,,,reduced virulence,,,,,,,,,,no,carbenicillin; nisin; bacitracin,carbenicillin: CHEBI:3393; nisin: CHEBI:71629; bacitracin: CHEBI:28669,,,,,gene deletion: partial; gene complementation,,,YVS,27993974,PubMed,10.1128/IAI.00925-16,Infect Immun.2017 Feb 23;85(3). pii: e00925-16,kmciver@umd.edu,"CpsY is involved in GAS resistance to innate immune cells of its human host, the loss of CpsY in GAS does not result in virulence defects in murine models of infection, suggesting that CpsY function in immune evasion is specific to the human host.",L A Vega 2017,2017,1 gene,Vega-2017-The Transcriptional Regulator CpsY I,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10188,PHI:7469,UniProt,C6DEJ2,GenBank,ACT12677,,,PC1,RplY,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,94108,Zantedeschia elliottiana (no common name found),cv. Black Magic,,,leaf,50S ribosomal protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28853642,PubMed,10.1094/PHYTO-04-17-0161-R,Phytopathology.2017 Aug 30:PHYTO04170161R,fanjq@njau.edu.cn,"The deletion mutant ΔrplY, exhibited reduced virulence, motility and plant cell wall-degrading enzyme production but not biofilm formation.",H Jiang 2017,2017,1 gene,Jiang-2017-The Ribosomal Protein RplY Is Requi,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10189,PHI:7469,UniProt,C6DEJ2,GenBank,ACT12677,,,PC1,RplY,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,leaf,50S ribosomal protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28853642,PubMed,10.1094/PHYTO-04-17-0161-R,Phytopathology.2017 Aug 30:PHYTO04170161R,fanjq@njau.edu.cn,"The deletion mutant ΔrplY, exhibited reduced virulence, motility and plant cell wall-degrading enzyme production but not biofilm formation.",H Jiang 2017,2017,1 gene,Jiang-2017-The Ribosomal Protein RplY Is Requi,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10190,PHI:7469,UniProt,C6DEJ2,GenBank,ACT12677,,,PC1,RplY,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,50S ribosomal protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28853642,PubMed,10.1094/PHYTO-04-17-0161-R,Phytopathology.2017 Aug 30:PHYTO04170161R,fanjq@njau.edu.cn,"The deletion mutant ΔrplY, exhibited reduced virulence, motility and plant cell wall-degrading enzyme production but not biofilm formation.",H Jiang 2017,2017,1 gene,Jiang-2017-The Ribosomal Protein RplY Is Requi,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10191,PHI:7470,UniProt,P22262,GenBank,AAA25291,,,EGD,prfA,,M7-prfAEGDe,,,,,1639,Listeria monocytogenes,1030009,M7,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,spleen; liver,surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26055558,PubMed,10.1099/jmm.0.000101,J Med Microbiol.2015 Aug;64(8):818-27,whfang@zju.edu.cn,"The low virulence of strain M7 was due to its defects in infecting host cells, possibly as a result of failed anchorage on the bacterial cells of surface proteins like InlB, a major protein involved in adhesion and invasion of pathogenic L. monocytogenes strains.",C Fang 2017,2017,1 gene,Fang-2015-Activation of PrfA results in overex,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10192,PHI:7470,UniProt,P22262,GenBank,AAA25291,,,EGD,prfA,,EGDe-prfAM7 PrfA*(G145S),,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,spleen; liver,surface protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26055558,PubMed,10.1099/jmm.0.000101,J Med Microbiol.2015 Aug;64(8):818-27,whfang@zju.edu.cn,"The low virulence of strain M7 was due to its defects in infecting host cells, possibly as a result of failed anchorage on the bacterial cells of surface proteins like InlB, a major protein involved in adhesion and invasion of pathogenic L. monocytogenes strains.",C Fang 2017,2017,1 gene,Fang-2015-Activation of PrfA results in overex,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10193,PHI:7471,UniProt,A0A0H3MDW1,GenBank,CAP04331,,,434/Bu,ChxR,,,,,,,813,Chlamydia trachomatis,759364,D-LC,ocular disease; sexually transmitted disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,28369275,PubMed,10.1093/femspd/ftx035,Pathog Dis. 2017 Apr 1;75(3),hcaldwell@niaid.nih.gov,"While ChxR null mutants exhibited no growth deficiencies in invitro, they did show significant differences in invivo growth using a mouse genital tract model.",C Yang 2017,2017,1 gene,Yang-2017-Chlamydia trachomatis ChxR is a tran,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10194,PHI:7472,UniProt,Q2A0P1,GenBank,ACY39283,,,BFOL-51,Avr2,,ΔspAvr2R45H,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,28857169,PubMed,10.1111/nph.14733,New Phytol.2017 Aug 31,mark.banfield@jic.ac.uk,"Transgenic tomato and Arabidopsis expressing either wild-type ΔspAvr2 (deleted signal peptide) or the ΔspAvr2R45H variant become hypersusceptible to fungal, and even bacterial infections, suggesting that Avr2 targets a conserved defense mechanism.",X Di 2017,2017,1 gene,Di-2017-Structure-function analysis of the Fus,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10195,PHI:7472,UniProt,Q2A0P1,GenBank,ACY39283,,,BFOL-51,Avr2,,ΔspAvr2R45H,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,reduced,no,,,,,,,other evidence: transgenic plants,,,YVS,28857169,PubMed,10.1111/nph.14733,New Phytol.2017 Aug 31,mark.banfield@jic.ac.uk,"Transgenic tomato and Arabidopsis expressing either wild-type ΔspAvr2 (deleted signal peptide) or the ΔspAvr2R45H variant become hypersusceptible to fungal, and even bacterial infections, suggesting that Avr2 targets a conserved defense mechanism.",X Di 2017,2017,1 gene,Di-2017-Structure-function analysis of the Fus,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10196,PHI:7472,UniProt,Q2A0P1,GenBank,ACY39283,,,BFOL-51,Avr2,,ΔspAvr2R45H,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,reduced,no,,,,,,,other evidence: transgenic plants,,,YVS,28857169,PubMed,10.1111/nph.14733,New Phytol.2017 Aug 31,mark.banfield@jic.ac.uk,"Transgenic tomato and Arabidopsis expressing either wild-type ΔspAvr2 (deleted signal peptide) or the ΔspAvr2R45H variant become hypersusceptible to fungal, and even bacterial infections, suggesting that Avr2 targets a conserved defense mechanism.",X Di 2017,2017,1 gene,Di-2017-Structure-function analysis of the Fus,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10197,PHI:7472,UniProt,Q2A0P1,GenBank,ACY39283,,,BFOL-51,Avr2,,ΔspAvr2R45H,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,reduced,no,,,,,,,other evidence: transgenic plants,,,YVS,28857169,PubMed,10.1111/nph.14733,New Phytol.2017 Aug 31,mark.banfield@jic.ac.uk,"Transgenic tomato and Arabidopsis expressing either wild-type ΔspAvr2 (deleted signal peptide) or the ΔspAvr2R45H variant become hypersusceptible to fungal, and even bacterial infections, suggesting that Avr2 targets a conserved defense mechanism.",X Di 2017,2017,1 gene,Di-2017-Structure-function analysis of the Fus,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10198,PHI:7472,UniProt,Q2A0P1,GenBank,ACY39283,,,BFOL-51,Avr2,,ΔspAvr2R45H,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,reduced,no,,,,,,,other evidence: transgenic plants,,,YVS,28857169,PubMed,10.1111/nph.14733,New Phytol.2017 Aug 31,mark.banfield@jic.ac.uk,"Transgenic tomato and Arabidopsis expressing either wild-type ΔspAvr2 (deleted signal peptide) or the ΔspAvr2R45H variant become hypersusceptible to fungal, and even bacterial infections, suggesting that Avr2 targets a conserved defense mechanism.",X Di 2017,2017,1 gene,Di-2017-Structure-function analysis of the Fus,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10199,PHI:7472,UniProt,Q2A0P1,GenBank,ACY39283,,,BFOL-51,Avr2,,ΔspAvr2R45H,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,reduced,no,,,,,,,other evidence: transgenic plants,,,YVS,28857169,PubMed,10.1111/nph.14733,New Phytol.2017 Aug 31,mark.banfield@jic.ac.uk,"Transgenic tomato and Arabidopsis expressing either wild-type ΔspAvr2 (deleted signal peptide) or the ΔspAvr2R45H variant become hypersusceptible to fungal, and even bacterial infections, suggesting that Avr2 targets a conserved defense mechanism.",X Di 2017,2017,1 gene,Di-2017-Structure-function analysis of the Fus,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10200,PHI:7472,UniProt,Q2A0P1,GenBank,ACY39283,,,BFOL-51,Avr2,,ΔspAvr2R45H,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici strain Fol007,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,reduced,no,,,,,,,other evidence: transgenic plants,,,YVS,28857169,PubMed,10.1111/nph.14733,New Phytol.2017 Aug 31,mark.banfield@jic.ac.uk,"Transgenic tomato and Arabidopsis expressing either wild-type ΔspAvr2 (deleted signal peptide) or the ΔspAvr2R45H variant become hypersusceptible to fungal, and even bacterial infections, suggesting that Avr2 targets a conserved defense mechanism.",X Di 2017,2017,1 gene,Di-2017-Structure-function analysis of the Fus,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10201,PHI:7472,UniProt,Q2A0P1,GenBank,ACY39283,,,BFOL-51,Avr2,,ΔspAvr2R45H,,,,,5507,Fusarium oxysporum,660025,Fo5176,Fusarium wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,reduced,no,,,,,,,other evidence: transgenic plants,,,YVS,28857169,PubMed,10.1111/nph.14733,New Phytol.2017 Aug 31,mark.banfield@jic.ac.uk,"Transgenic tomato and Arabidopsis expressing either wild-type ΔspAvr2 (deleted signal peptide) or the ΔspAvr2R45H variant become hypersusceptible to fungal, and even bacterial infections, suggesting that Avr2 targets a conserved defense mechanism.",X Di 2017,2017,1 gene,Di-2017-Structure-function analysis of the Fus,BATCH_073A,2017-09-01,MC,,,,,,,,,,,,,
,,Record 10202,PHI:7473,UniProt,P18177,GenBank,CAA63562,,,VPI10463,TcdB,,Y284A and D286/288N,,,,,1496,Clostridioides difficile,,,pseudomembranous colitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,major virulent factor toxin which induces autophagy response in host cells through its glucosyltransferase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28874882,PubMed,10.1038/s41598-017-11336-4,Sci Rep.2017 Sep 5;7(1):10532,wswei@pku.edu.cn,"Host gene alteration data available- HeLa/ATG7-/-, MEF/atg7-/- and MEF/tsc2-/-. The glucosyltransferase activity of the GT domain, which is reported to be responsible for the disruption of the cytoskeleton in host cells, was necessary and sufficient to induce autophagy upon TcdB exposure. Pathogen formerly called Clostridium difficile",R He 2017,2017,1 gene,He-2017-Glucosyltransferase Activity of Clostr,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10203,PHI:7474,UniProt,Q9X4P2,GenBank,AF116285_1,,,UCBPP-PA14,PA0336 (RppH),,,,,,,287,Pseudomonas aeruginosa,,PAO1161,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,nudix-type RNA pyrophosphohydrolase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,28833678,PubMed,10.1111/mmi.13771,Mol Microbiol.2017 Nov;106(3):381-394,elzbietak@ibb.waw.pl,The catalytic activity of Pa RppH was essential for its cellular function.,M Kujawa 2017,2017,1 gene,Kujawa-2017-Nudix-type RNA pyrophosphohydrolas,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10204,PHI:7475,UniProt,Q48413,GenBank,AIK80589,,,ATCC 43816 KPPR1,ramA (VK055_1983),,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"bacterial regulatory helix-turn-helix, AraC family protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10205,PHI:7476,UniProt,Q48412,GenBank,AIK80590,,,ATCC 43816 KPPR1,RomA (VK055_1984),,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,metallo-beta-lactamase superfamily protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10206,PHI:7477,UniProt,D8L2S4,GenBank,AIK80588,,,ATCC 43816 KPPR1,orf82 (VK055_1982),,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10207,PHI:7475,UniProt,Q48413,GenBank,AIK80589,,,ATCC 43816 KPPR1,ramA (VK055_1983),,,,,,PHI:7476; PHI:7477,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"bacterial regulatory helix-turn-helix, AraC family protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10208,PHI:7476,UniProt,Q48412,GenBank,AIK80590,,,ATCC 43816 KPPR1,RomA (VK055_1984),,,,,,PHI:7475; PHI:7477,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,metallo-beta-lactamase superfamily protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10209,PHI:7477,UniProt,D8L2S4,GenBank,AIK80588,,,ATCC 43816 KPPR1,orf82 (VK055_1982),,,,,,PHI:7475; PHI:7476,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10210,PHI:7478,UniProt,A0A060VFL5,GenBank,AIK80532,,,ATCC 43816 KPPR1,FepB (VK055_1926),,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,periplasmic enterobactin transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10211,PHI:7479,UniProt,W9BNM8,GenBank,AIK80529,,,ATCC 43816 KPPR1,entB (VK055_1923),,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,isochorismatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10212,PHI:7480,UniProt,W9BHK2,GenBank,CDO15334,,,Kp52.145,ybtS,,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,siderophore protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10213,PHI:7479,UniProt,W9BNM8,GenBank,AIK80529,,,ATCC 43816 KPPR1,entB (VK055_1923),,,,,,PHI:7480,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,isochorismatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10214,PHI:7480,UniProt,W9BHK2,GenBank,CDO15334,,,Kp52.145,ybtS,,,,,,PHI:7479,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,siderophore protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10215,PHI:7481,UniProt,W1B397,GenBank,AIK80533,,,ATCC 43816 KPPR1,entS (VK055_1927),,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,enterobactin exporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10216,PHI:7482,,no data found,GenBank,AIK80539,,,ATCC 43816 KPPR1,fes (VK055_1933),,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,enterochelin esterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10217,PHI:7483,UniProt,W9BNM7,GenBank,AIK80534,,,ATCC 43816 KPPR1,FepD (VK055_1928),,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,ferric enterobactin transport system permease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10218,PHI:7484,,no data found,GenBank,AIK80527,,,ATCC 43816 KPPR1,YbdB2 (VK055_1921),,,,,,PHI:7485; PHI:7479; PHI:7486; PHI:7487,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,proofreading thioesterase in enterobactin biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10219,PHI:7485,UniProt,W9BF24,GenBank,AIK80528,,,ATCC 43816 KPPR1,EntA (VK055_1922),,,,,,PHI:7484; PHI:7479; PHI:7486; PHI:7487,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10220,PHI:7479,UniProt,W9BNM8,GenBank,AIK80529,,,ATCC 43816 KPPR1,entB (VK055_1923),,,,,,PHI:7484; PHI:7485; PHI:7486; PHI:7487,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,isochorismatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10221,PHI:7486,UniProt,W9B580,GenBank,AIK80530,,,ATCC 43816 KPPR1,entE (VK055_1924),,,,,,PHI:7484; PHI:7485; PHI:7479; PHI:7487,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"(2,3-dihydroxybenzoyl)adenylate synthase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10222,PHI:7487,UniProt,A0A085DFX7,GenBank,AIK80531,,,ATCC 43816 KPPR1,EntC (VK055_1925),,,,,,PHI:7484; PHI:7485; PHI:7479; PHI:7486,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,isochorismate synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10223,PHI:7488,,no data found,GenBank,AIK80593,,,ATCC 43816 KPPR1,VK055_1987,,,,,,PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,oxygen-insensitive NADPH nitroreductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10224,PHI:7489,,no data found,GenBank,AIK80592,,,ATCC 43816 KPPR1,VK055_1986,,,,,,PHI:7488; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10225,PHI:7490,,no data found,GenBank,AIK80591,,,ATCC 43816 KPPR1,VK055_1985,,,,,,PHI:7488; PHI:7489; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"bacterial transcriptional regulator, TetR family",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10226,PHI:7476,UniProt,Q48412,GenBank,AIK80590,,,ATCC 43816 KPPR1,RomA (VK055_1984),,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,metallo-beta-lactamase superfamily protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10227,PHI:7475,UniProt,Q48413,GenBank,AIK80589,,,ATCC 43816 KPPR1,ramA (VK055_1983),,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"bacterial regulatory helix-turn-helix, AraC family protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10228,PHI:7477,UniProt,D8L2S4,GenBank,AIK80588,,,ATCC 43816 KPPR1,orf82 (VK055_1982),,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10229,PHI:7491,,no data found,GenBank,AIK80587,,,ATCC 43816 KPPR1,VK055_1981,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,putative aldo/keto reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10230,PHI:7492,UniProt,A0A076ZK37,GenBank,AIK80586,,,ATCC 43816 KPPR1,VK055_1980,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"HADa ATPase, P type",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10231,PHI:7493,,no data found,GenBank,AIK80585,,,ATCC 43816 KPPR1,VK055_1979,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"efflux transporter, RND family, MFP subunit",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10232,PHI:7494,,no data found,GenBank,AIK80584,,,ATCC 43816 KPPR1,BepE (VK055_1978),,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,efflux pump membrane transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10233,PHI:7495,,no data found,GenBank,AIK80583,,,ATCC 43816 KPPR1,VK055_1977,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10234,PHI:7496,UniProt,A0A086IIR8,GenBank,AIK80582,,,ATCC 43816 KPPR1,YbdK (VK055_1976),,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,gamma-glutamyl cysteine ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10235,PHI:7497,UniProt,A0A076ZK32,GenBank,AIK80581,,,ATCC 43816 KPPR1,VK055_1975,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10236,PHI:7498,,no data found,GenBank,AIK80580,,,ATCC 43816 KPPR1,VK055_1974,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,bacterial extracellular solute-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10237,PHI:7499,,no data found,GenBank,AIK80579,,,ATCC 43816 KPPR1,VK055_1973,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,binding-protein-dependent transport system inner membrane component,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10238,PHI:7500,,no data found,GenBank,AIK80578,,,ATCC 43816 KPPR1,VK055_1972,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,binding-protein-dependent transport system inner membrane component,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10239,PHI:7501,,no data found,GenBank,AIK80577,,,ATCC 43816 KPPR1,VK055_1971,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"oligopeptide/dipeptide ABC transporter, ATP binding",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10240,PHI:7502,,no data found,GenBank,AIK80576,,,ATCC 43816 KPPR1,VK055_1970,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"oligopeptide/dipeptide ABC transporter, ATP binding",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10241,PHI:7503,,no data found,GenBank,AIK80575,,,ATCC 43816 KPPR1,VK055_1969,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"amidase, hydatoinase/carbamoylase family protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10242,PHI:7504,,no data found,GenBank,AIK80574,,,ATCC 43816 KPPR1,VK055_1968,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,EamA-like transporter family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10243,PHI:7505,,no data found,GenBank,AIK80572,,,ATCC 43816 KPPR1,VK055_1967,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"bacterial transcriptional regulator, GntR family protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10244,PHI:7506,,no data found,GenBank,AIK80573,,,ATCC 43816 KPPR1,VK055_1966,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"bacterial transcriptional regulator, GntR family protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10245,PHI:7507,,no data found,GenBank,AIK80571,,,ATCC 43816 KPPR1,VK055_1965,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7508; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,bacterial extracellular solute-binding,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10246,PHI:7508,,no data found,GenBank,AIK80570,,,ATCC 43816 KPPR1,VK055_1964,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7509; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"ABC transporter, permease",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10247,PHI:7509,,no data found,GenBank,AIK80569,,,ATCC 43816 KPPR1,VK055_1963,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7510; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"ABC-type amino acid transport system, permease",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10248,PHI:7510,,no data found,GenBank,AIK80568,,,ATCC 43816 KPPR1,VK055_1962,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7511; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,ABC transporter family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10249,PHI:7511,UniProt,A0A076ZHT9,GenBank,AIK80567,,,ATCC 43816 KPPR1,VK055_1961,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7512,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,serine 3-dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10250,PHI:7512,,no data found,GenBank,AIK80566,,,ATCC 43816 KPPR1,VK055_1960,,,,,,PHI:7488; PHI:7489; PHI:7490; PHI:7476; PHI:7475; PHI:7477; PHI:7491; PHI:7492; PHI:7493; PHI:7494; PHI:7495; PHI:7496; PHI:7497; PHI:7498; PHI:7499; PHI:7500; PHI:7501; PHI:7502; PHI:7503; PHI:7504; PHI:7505; PHI:7506; PHI:7507; PHI:7508; PHI:7509; PHI:7510; PHI:7511,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,aminotransferase class III family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10251,PHI:7513,,no data found,GenBank,AIK80565,,,ATCC 43816 KPPR1,VK055_1959,,,,,,PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,ABC transporter family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10252,PHI:7514,,no data found,GenBank,AIK80564,,,ATCC 43816 KPPR1,VK055_1958,,,,,,PHI:7513; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,ABC transporter family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10253,PHI:7515,,no data found,GenBank,AIK80563,,,ATCC 43816 KPPR1,VK055_1957,,,,,,PHI:7513; PHI:7514; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,oligopeptide transport permease family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10254,PHI:7516,,no data found,GenBank,AIK80562,,,ATCC 43816 KPPR1,VK055_1956,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,binding protein-dependent transport system inner membrane component family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10255,PHI:7517,,no data found,GenBank,AIK80561,,,ATCC 43816 KPPR1,VK055_1955,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,bacterial extracellular solute-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10256,PHI:7518,,no data found,GenBank,AIK80560,,,ATCC 43816 KPPR1,VK055_1954,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,acetyltransferase family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10257,PHI:7519,,no data found,GenBank,AIK80559,,,ATCC 43816 KPPR1,VK055_1953,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,choline dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10258,PHI:7520,UniProt,A0A076ZMY5,GenBank,AIK80558,,,ATCC 43816 KPPR1,VK055_1952,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,betaine aldehyde dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10259,PHI:7521,UniProt,B5Y006,GenBank,AIK80557,,,ATCC 43816 KPPR1,BetI (VK055_1951),,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10260,PHI:7522,,no data found,GenBank,AIK80556,,,ATCC 43816 KPPR1,VK055_1950,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"transporter, betaine/carnitine/choline transporter family protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10261,PHI:7523,UniProt,W9B5X1,GenBank,AIK80555,,,ATCC 43816 KPPR1,ykfE (VK055_1949),,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,inhibitor of vertebrate C-type lysozyme,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10262,PHI:7524,,no data found,GenBank,AIK80553,,,ATCC 43816 KPPR1,VK055_1948,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"bacterial regulatory helix-turn-helix, LysR family protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10263,PHI:7525,,no data found,GenBank,AIK80554,,,ATCC 43816 KPPR1,VK055_1947,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,mechanosensitive ion channel family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10264,PHI:7526,,no data found,GenBank,AIK80552,,,ATCC 43816 KPPR1,VK055_1946,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,hypothetical kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10265,PHI:7527,,no data found,GenBank,AIK80551,,,ATCC 43816 KPPR1,VK055_1945,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,glycerol kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10266,PHI:7528,UniProt,A0A076ZPI8,GenBank,AIK80550,,,ATCC 43816 KPPR1,VK055_1944,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"L-fucose isomerase, C-terminal domain protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10267,PHI:7529,,no data found,GenBank,AIK80549,,,ATCC 43816 KPPR1,VK055_1943,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"transketolase, pyrimidine binding domain protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10268,PHI:7530,,no data found,GenBank,AIK80548,,,ATCC 43816 KPPR1,VK055_1942,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"thiamine pyrophosphate enzyme, C-terminal TPPb binding domain protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10269,PHI:7531,,no data found,GenBank,AIK80546,,,ATCC 43816 KPPR1,VK055_1941,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10270,PHI:7532,,no data found,GenBank,AIK80547,,,ATCC 43816 KPPR1,VK055_1940,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,putative transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10271,PHI:7533,UniProt,A0A076ZPI5,GenBank,AIK80545,,,ATCC 43816 KPPR1,VK055_1939,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7534; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,branched-chain amino acid transport system/permease component family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10272,PHI:7534,UniProt,W1ATL3,GenBank,AIK80544,,,ATCC 43816 KPPR1,CcmA (VK055_1938),,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7535; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"heme ABC exporter, ATP-binding protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10273,PHI:7535,,no data found,GenBank,AIK80543,,,ATCC 43816 KPPR1,VK055_1937,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7536; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10274,PHI:7536,,no data found,GenBank,AIK80542,,,ATCC 43816 KPPR1,VK055_1936,,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7537; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,periplasmic binding and sugar binding domain of LacI family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10275,PHI:7537,UniProt,B5XZZ0,GenBank,AIK80541,,,ATCC 43816 KPPR1,EntD (VK055_1935),,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7538,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,4'-phosphopantetheinyl transferase superfamily protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10276,PHI:7538,UniProt,W9B570,GenBank,AIK80540,,,ATCC 43816 KPPR1,FepA (VK055_1934),,,,,,PHI:7513; PHI:7514; PHI:7515; PHI:7516; PHI:7517; PHI:7518; PHI:7519; PHI:7520; PHI:7521; PHI:7522; PHI:7523; PHI:7524; PHI:7525; PHI:7526; PHI:7527; PHI:7528; PHI:7529; PHI:7530; PHI:7531; PHI:7532; PHI:7533; PHI:7534; PHI:7535; PHI:7536; PHI:7537,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,TonB-dependent siderophore receptor family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10277,PHI:7482,,no data found,GenBank,AIK80539,,,ATCC 43816 KPPR1,fes (VK055_1933),,,,,,PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,enterochelin esterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10278,PHI:7539,,no data found,GenBank,AIK80538,,,ATCC 43816 KPPR1,VK055_1932,,,,,,PHI:7482; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,MbtH-like family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10279,PHI:7540,UniProt,B5XZY6,GenBank,AIK80537,,,ATCC 43816 KPPR1,EntF (VK055_1931),,,,,,PHI:7482; PHI:7539; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,amino acid adenylation domain protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10280,PHI:7541,UniProt,W9B5Y9,GenBank,AIK80536,,,ATCC 43816 KPPR1,FepC (VK055_1930),,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"ferric vibriobactin ABC transporter, ATP-binding protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10281,PHI:7542,UniProt,W9B576,GenBank,AIK80535,,,ATCC 43816 KPPR1,FepG (VK055_1929),,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,ferric enterobactin transport system permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10282,PHI:7483,UniProt,W9BNM7,GenBank,AIK80534,,,ATCC 43816 KPPR1,FepD (VK055_1928),,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,ferric enterobactin transport system permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10283,PHI:7481,UniProt,W1B397,GenBank,AIK80533,,,ATCC 43816 KPPR1,entS (VK055_1927),,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,enterobactin exporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10284,PHI:7478,UniProt,A0A060VFL5,GenBank,AIK80532,,,ATCC 43816 KPPR1,FepB (VK055_1926),,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,periplasmic enterobactin transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10285,PHI:7487,UniProt,A0A085DFX7,GenBank,AIK80531,,,ATCC 43816 KPPR1,EntC (VK055_1925),,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,isochorismate synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10286,PHI:7486,UniProt,W9B580,GenBank,AIK80530,,,ATCC 43816 KPPR1,entE (VK055_1924),,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"(2,3-dihydroxybenzoyl)adenylate synthase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10287,PHI:7479,UniProt,W9BNM8,GenBank,AIK80529,,,ATCC 43816 KPPR1,entB (VK055_1923),,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,isochorismatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10288,PHI:7485,UniProt,W9BF24,GenBank,AIK80528,,,ATCC 43816 KPPR1,EntA (VK055_1922),,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10289,PHI:7484,,no data found,GenBank,AIK80527,,,ATCC 43816 KPPR1,YbdB2 (VK055_1921),,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,proofreading thioesterase in enterobactin biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10290,PHI:7543,,no data found,GenBank,AIK80526,,,ATCC 43816 KPPR1,VK055_1920,,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,carbon starvation CstA family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10291,PHI:7544,,no data found,GenBank,AIK80524,,,ATCC 43816 KPPR1,VK055_1919,,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,helix-turn-helix family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10292,PHI:7545,,no data found,GenBank,AIK80525,,,ATCC 43816 KPPR1,VK055_1918,,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10293,PHI:7546,,no data found,GenBank,AIK80523,,,ATCC 43816 KPPR1,VK055_1917,,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,plasmid stabilization system family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10294,PHI:7547,,no data found,GenBank,AIK80522,,,ATCC 43816 KPPR1,VK055_1916,,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7548; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,short-chain dehydrogenase family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10295,PHI:7548,,no data found,GenBank,AIK80521,,,ATCC 43816 KPPR1,VK055_1915,,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7549; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10296,PHI:7549,,no data found,GenBank,AIK80520,,,ATCC 43816 KPPR1,VK055_1914,,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7550; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,ABC transporter family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10297,PHI:7550,,no data found,GenBank,AIK80519,,,ATCC 43816 KPPR1,VK055_1913,,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7551; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,branched-chain amino acid transport system/permease component family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10298,PHI:7551,,no data found,GenBank,AIK80518,,,ATCC 43816 KPPR1,VK055_1912,,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7552,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,periplasmic binding and sugar binding domain of LacI family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10299,PHI:7552,,no data found,GenBank,AIK80517,,,ATCC 43816 KPPR1,VK055_1911,,,,,,PHI:7482; PHI:7539; PHI:7540; PHI:7541; PHI:7542; PHI:7483; PHI:7481; PHI:7478; PHI:7487; PHI:7486; PHI:7479; PHI:7485; PHI:7484; PHI:7543; PHI:7544; PHI:7545; PHI:7546; PHI:7547; PHI:7548; PHI:7549; PHI:7550; PHI:7551,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,LVIVD repeat family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28861522,PubMed,10.1128/mSphere.00341-17,mSphere.2017 Aug 23;2(4). pii: e00341-17,vlmiller@med.unc.edu,"The virulence defect of the smr mutant could be attributed to the loss of FepB, a periplasmic protein required for import of the siderophore enterobactin.",M Palacios 2017,2017,78 genes,Palacios-2017-A Serendipitous Mutation Reveals,BATCH_073B,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10300,PHI:7553,,no data found,,,,,,MarS,,,,,,,1314,Streptococcus pyogenes,294934,group A serotype M49 strain 591,skin lesion,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; lung; kidney; spleen,Mga-activating regulatory small RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28947755,PubMed,10.1038/s41598-017-12507-z,Sci Rep.2017 Sep 25;7(1):12241,nadja.patenge@med.uni-rostock.de,Lack of MarS results in decreased survival of GAS M49 591 in human blood.,R Pappesch 2017,2017,1 gene,Pappesch-2017-The Regulatory Small RNA MarS Su,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10301,PHI:7554,UniProt,P49988,GenBank,AAA19793,,,PAK,RpoN,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,RNA polymerase sigma-54 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28974743,PubMed,10.1038/s41598-017-12667-y,Sci Rep.2017 Oct 3;7(1):12615,ctnomura@esf.edu,Blocking RpoN consensus promoter sites is an effective strategy for abrogation of P. aeruginosa virulence.,M G Lloyd 2017,2017,1 gene,Lloyd-2017-Targeting the alternative sigma fac,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10302,PHI:7555,UniProt,D0MSJ4,GenBank,EEY58463,,,T30-4,PITG_01131,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Bintje,,,leaf,putative cell wall protein,,,,reduced virulence,,yes,,,,,,,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28935716,PubMed,10.1074/mcp.M116.065656,Mol Cell Proteomics.2017 Sep 21. pii: mcp.M116.065656,svante.resjo@slu.se,"PiACWP 1-3 proteins are involved in germ tube and appressorium formation and thus, silencing them directly impacts the ability of P. infestans to initiate infection.",S Resjö 2017,2017,3 genes,Resjo-2017-Proteomic analysis of Phytophthora,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10303,PHI:7556,UniProt,D0MSJ5,GenBank,EEY58464,,,T30-4,PITG_01132,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Bintje,,,leaf,putative cell wall protein,,,,reduced virulence,,yes,,,,,,,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28935716,PubMed,10.1074/mcp.M116.065656,Mol Cell Proteomics.2017 Sep 21. pii: mcp.M116.065656,svante.resjo@slu.se,"PiACWP 1-3 proteins are involved in germ tube and appressorium formation and thus, silencing them directly impacts the ability of P. infestans to initiate infection.",S Resjö 2017,2017,3 genes,Resjo-2017-Proteomic analysis of Phytophthora,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10304,PHI:7557,UniProt,D0NSZ3,GenBank,EEY64705,,,T30-4,PITG_16135,,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Bintje,,,leaf,putative cell wall protein,,,,reduced virulence,,yes,,,,,,,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28935716,PubMed,10.1074/mcp.M116.065656,Mol Cell Proteomics.2017 Sep 21. pii: mcp.M116.065656,svante.resjo@slu.se,"PiACWP 1-3 proteins are involved in germ tube and appressorium formation and thus, silencing them directly impacts the ability of P. infestans to initiate infection.",S Resjö 2017,2017,3 genes,Resjo-2017-Proteomic analysis of Phytophthora,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10305,PHI:7558,UniProt,F9WWD1,GenBank,EGP92529,,,IPO323,ZtGT2,chromosome 1,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,glycosyltransferase,,,,loss of pathogenicity,,,,,,,,aberrant,,no,calcoflour white; caspofungin; H2O2; sorbitol,calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,29020037,PubMed,10.1371/journal.ppat.1006672,PLoS Pathog.2017 Oct 11;13(10):e1006672,Jason.rudd@rothamsted.ac.uk,The inability of Zymoseptoria tritici and Fusarium graminearum to extend surface hyphae resulted in a complete loss of virulence on plants.,R King 2017,2017,2 genes,King-2017-A conserved fungal glycosyltransfera,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10306,PHI:7559,UniProt,I1RB03,GenBank,CEF72686,,,PH-1,FgGT2,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,glycosyltransferase,,,,loss of pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full,,,YVS,29020037,PubMed,10.1371/journal.ppat.1006672,PLoS Pathog.2017 Oct 11;13(10):e1006672,Jason.rudd@rothamsted.ac.uk,The inability of Zymoseptoria tritici and Fusarium graminearum to extend surface hyphae resulted in a complete loss of virulence on plants.,R King 2017,2017,2 genes,King-2017-A conserved fungal glycosyltransfera,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10307,PHI:7560,UniProt,B2FJV0,GenBank,CAQ43987,,,K279a,smlt0387,,,,,,,40324,Stenotrophomonas maltophilia,522373,K279a,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28965241,PubMed,10.1007/s00203-017-1433-7,Arch Microbiol. 2017 Sep 30,s.an@dundee.ac.uk,"Loss by mutation of Ax21 leads to reduced motility, reduced biofilm formation, reduced tolerance to the antibiotic tobramycin and reduced virulence to larvae of Galleria mellonella.",S Q An 2017,2017,1 gene,An-2017-The Ax21 protein influences virulence,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10308,PHI:7561,UniProt,U3PYY2,GenBank,AGW82398,,,MIL31,PLC1,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),,,,leaf,phospholipase C,,,,reduced virulence,,,,,,reduced,,reduced,,no,CaCl2; calcium nitrate; lithium chloride; neomycin,CaCl2: CHEBI:3312; calcium nitrate: CHEBI:64205; lithium chloride: CHEBI:48607; neomycin: CHEBI:7507,,,,,gene disruption; gene complementation,,,YVS,24763426,PubMed,10.1099/mic.0.077818-0,Microbiology. 2014 Jul;160(Pt 7):1453-65,krchung@ufl.edu,"PLC1 and CAL1 were required for vegetative growth, conidial formation and pathogenesis in citrus.",H C Tsai 2014,2014,2 genes,Tsai-2014-Calcineurin phosphatase and phosphol,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10309,PHI:7562,UniProt,U3Q4A0,GenBank,AGW82397,,,MIL31,CAL1,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),,,,leaf,calcineurin phosphatase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene disruption; gene complementation,,,YVS,24763426,PubMed,10.1099/mic.0.077818-0,Microbiology. 2014 Jul;160(Pt 7):1453-65,krchung@ufl.edu,"PLC1 and CAL1 were required for vegetative growth, conidial formation and pathogenesis in citrus.",H C Tsai 2014,2014,2 genes,Tsai-2014-Calcineurin phosphatase and phosphol,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10310,PHI:7563,UniProt,Q63T64,GenBank,CAH36108,,,K96243,BPSL2105,chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,putative phage-shock protein A (PspA) homologue,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26374246,PubMed,10.1099/mic.0.000175,Microbiology. 2015 Nov;161(11):2192-203,sjsouthern@mail.dstl.gov.uk,"B. pseudomallei BPSL2105 encodes a PspA-like protein that was induced in response to extreme heat shock, similar to the PspA protein of E. coli and it is important for survival during stationary phase and during infection of macrophages.",S J Southern 2015,2015,1 gene,Southern-2015-Evaluating the Role of Phage-Sho,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10311,PHI:7564,UniProt,J4UU56,GenBank,EJP69472,,,ARSEF 2860,BbmtrA,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative methyltransferase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25194143,PubMed,10.1099/mic.0.078469-0,Microbiology. 2014 Nov;160(Pt 11):2526-37,keyhani@ufl.edu,"Loss of BbmtrA resulted in pleiotropic effects including reduced germination, growth and conidiation, with growing mycelia displaying greater branching than the WT parent.",Y Qin 2014,2014,1 gene,"Qin-2014-A putative methyltransferase, mtrA, c",BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10312,PHI:7565,UniProt,Q9UWF6,GenBank,AAC72296,,,SS,Plb1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phospholipase B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,11535799,PubMed,10.1099/00221287-147-9-2585,Microbiology. 2001 Sep;147(Pt 9):2585-97,mag3@po.cwru.edu,Histological examinations and analysis of c.f.u. of the pathogen in liver homogenates revealed that the parental and revertant strains were able to invade and traverse the GI mucosa to a significantly greater extent than the plb1 null mutant.,P K Mukherjee 2001,2001,1 gene,Mukherjee-2001-Reintroduction of the PLB1 gene,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10313,PHI:7565,UniProt,Q9UWF6,GenBank,AAC72296,,,SS,Plb1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),Crl:CFW,,,liver; stomach,phospholipase B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,11535799,PubMed,10.1099/00221287-147-9-2585,Microbiology. 2001 Sep;147(Pt 9):2585-97,mag3@po.cwru.edu,Histological examinations and analysis of c.f.u. of the pathogen in liver homogenates revealed that the parental and revertant strains were able to invade and traverse the GI mucosa to a significantly greater extent than the plb1 null mutant.,P K Mukherjee 2001,2001,1 gene,Mukherjee-2001-Reintroduction of the PLB1 gene,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10314,PHI:7566,,no data found,,,,,,Bbcal1,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,caleosin,,,,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene mutation,,,YVS,27655425,PubMed,10.1099/mic.0.000375,Microbiology. 2016 Nov;162(11):1913-1921,keyhani@ufl.edu,"In topical bioassays, the ΔBbcal1 mutant displayed LD50 values 5-40-fold higher than the WT depending upon the growth substrate, with ΔBbcal1 conidia derived from SDAY unable to effectively penetrate the host cuticle, in contrast, intrahaemocoel injection bioassays that bypass cuticle penetration events revealed only minor effects on virulence for either WT or ΔBbcal1 conidia.",A Ortiz-Urquiza 2016,2016,1 gene,Ortiz-Urquiza-2016-Growth substrates and caleo,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10315,PHI:7567,UniProt,A0A0H2ZEM3,GenBank,ABJ12770,,,UCBPP-PA14,EprS,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneum,autotransporter serine protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,YVS,26678838,PubMed,10.1099/mic.0.000228,Microbiology. 2016 Feb;162(2):318-29,yutaka@med.kurume-u.ac.jp,Disruption of eprS resulted in reduced swimming and swarming motilities of P. aeruginosa.,Y Kida 2015,2015,1 gene,"Kida-2015-EprS, an autotransporter serine prot",BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10316,PHI:7568,UniProt,Q0U4L8,GenBank,EAT79180,,,SN15,HOG1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Calingiri,,,leaf,mitogen-activated protein kinase,,,HOG1 mitogen-activated protein kinase signalling pathway,unaffected pathogenicity,,,,,,reduced,,wild type,,no,iprodione; procymidone; fludioxonil; tebuconazole; NaCl; H2O2,"iprodione: CHEBI:28909, CAS:36734-19-7; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; tebuconazole: CHEBI:81781; NaCl: CHEBI:26710; H2O2: CHEBI:16240",,,,,gene deletion: full; gene complementation,,,YVS,26978567,PubMed,10.1099/mic.0.000280,Microbiology. 2016 Jun;162(6):1023-36,Kar-Chun.Tan@curtin.edu.au,"Both Δnik1 and Δhog1 mutants retained the ability to infect and cause necrotic lesions on wheat, wherein, HOG1, but not NIK1, was required for tolerance to heat stress in vitro and for full pycnidiation in planta.",E John 2016,2016,2 genes,John-2016-Dissecting the role of histidine kin,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10317,PHI:7569,UniProt,Q0U9D3,GenBank,EAT81339,,,SN15,NIK1,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Calingiri,,,leaf,histidine kinase,,,HOG1 mitogen-activated protein kinase signalling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,iprodione; procymidone; fludioxonil; tebuconazole; NaCl; H2O2,"iprodione: CHEBI:28909, CAS:36734-19-7; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; tebuconazole: CHEBI:81781; NaCl: CHEBI:26710; H2O2: CHEBI:16240",,,,,gene deletion: full; gene complementation,,,YVS,26978567,PubMed,10.1099/mic.0.000280,Microbiology. 2016 Jun;162(6):1023-36,Kar-Chun.Tan@curtin.edu.au,"Both Δnik1 and Δhog1 mutants retained the ability to infect and cause necrotic lesions on wheat, wherein, HOG1, but not NIK1, was required for tolerance to heat stress in vitro and for full pycnidiation in planta.",E John 2016,2016,2 genes,John-2016-Dissecting the role of histidine kin,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10318,PHI:7570,UniProt,W9BND0,GenBank,CDO12935,,,Kp52.145,yfiR,,,,,,,573,Klebsiella pneumoniae,,LM21,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,negative regulator of YfiBNR system,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,amikacin; ciprofloxacin; imipenem; meropenem,amikacin: CHEBI:2637; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,25261190,PubMed,10.1099/mic.0.081992-0,Microbiology. 2014 Dec;160(Pt 12):2595-606,mzambrano@corpogen.org,"YfiRNB operon was implicated in the production of exopolysaccharides that alter cell surface characteristics and the capacity to form biofilms - a phenotype that does not necessarily correlate with properties related with survival, such as resistance to antibiotics.",M G Huertas 2014,2014,3 genes,Huertas-2014-The Klebsiella pneumoniae yfiRNB,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10319,PHI:7571,UniProt,W9B3Z6,GenBank,CDO12934,,,Kp52.145,yfiN,,,,,,,573,Klebsiella pneumoniae,,LM21,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,c-di-GMP turnover enzyme,,,,unaffected pathogenicity,,,,,,,,,,no,amikacin; ciprofloxacin; imipenem; meropenem,amikacin: CHEBI:2637; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,25261190,PubMed,10.1099/mic.0.081992-0,Microbiology. 2014 Dec;160(Pt 12):2595-606,mzambrano@corpogen.org,"YfiRNB operon was implicated in the production of exopolysaccharides that alter cell surface characteristics and the capacity to form biofilms - a phenotype that does not necessarily correlate with properties related with survival, such as resistance to antibiotics.",M G Huertas 2014,2014,3 genes,Huertas-2014-The Klebsiella pneumoniae yfiRNB,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10320,PHI:7572,UniProt,W9BJ64,GenBank,CDO16329,,,Kp52.145,yfiB,,,,,,,573,Klebsiella pneumoniae,,LM21,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,outer membrane lipoprotein which acts as a sensor of YfiBNR system,,,,unaffected pathogenicity,,,,,,,,,,no,amikacin; ciprofloxacin; imipenem; meropenem,amikacin: CHEBI:2637; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,25261190,PubMed,10.1099/mic.0.081992-0,Microbiology. 2014 Dec;160(Pt 12):2595-606,mzambrano@corpogen.org,"YfiRNB operon was implicated in the production of exopolysaccharides that alter cell surface characteristics and the capacity to form biofilms - a phenotype that does not necessarily correlate with properties related with survival, such as resistance to antibiotics.",M G Huertas 2014,2014,3 genes,Huertas-2014-The Klebsiella pneumoniae yfiRNB,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10321,PHI:7573,UniProt,Q7CIZ1,GenBank,CAL20306,,,CO92,MgtB,,,,,,,632,Yersinia pestis,,GB,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,magnesium ion transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25234474,PubMed,10.1099/mic.0.080556-0,Microbiology. 2014 Dec;160(Pt 12):2710-7,pcoyston@dstl.gov.uk,MgtB was required for macrophage invasion by Y.pestis but not Y. pseudotuberculsis.,D C Ford 2014,2014,1 gene,Ford-2014-The importance of the magnesium tran,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10322,PHI:7573,UniProt,Q669S4,GenBank,CAH21648,,,IP 32953,MgtB,,,,,,,633,Yersinia pseudotuberculosis,,IP32953,zoonotic infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,magnesium ion transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25234474,PubMed,10.1099/mic.0.080556-0,Microbiology. 2014 Dec;160(Pt 12):2710-7,pcoyston@dstl.gov.uk,MgtB was required for macrophage invasion by Y.pestis but not Y. pseudotuberculsis.,D C Ford 2014,2014,1 gene,Ford-2014-The importance of the magnesium tran,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10323,PHI:7574,UniProt,Q9I5N6,GenBank,AE004504_3,,,PAO1,PdtA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,hypothetical exoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,25009238,PubMed,10.1099/mic.0.079616-0,Microbiology. 2014 Sep;160(Pt 9):1940-52,sbigot@imm.cnrs.fr,"It was demonstrated that PdtA is implicated in the virulence of P. aeruginosa, however, the function played by PdtA during C. elegans infection is still unknown.",L M Faure 2014,2014,1 gene,Faure-2014-Characterization of a novel Two-Par,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10324,PHI:7575,UniProt,Q8ZJY5,GenBank,AAL23350,,,LT2; SGSC 1412; ATCC 700720,yjiY,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,Peyer's gland; cecum,peptide-utilizing carbon starvation protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26497384,PubMed,10.1099/mic.0.000204,Microbiology. 2015 Oct 22,dipa@mcbl.iisc.ernet.in,"Systemic infection in the mouse model did not depend on yjiY, as the presence of flagella is dispensable for systemic infection by Salmonella in the mouse model.",P Garai 2015,2015,3 genes,Garai-2015-Peptide utilizing carbon starvation,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10325,PHI:7576,UniProt,P06179,GenBank,AAL20871,,,LT2; SGSC 1412; ATCC 700720,fliC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cecum,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,26497384,PubMed,10.1099/mic.0.000204,Microbiology. 2015 Oct 22,dipa@mcbl.iisc.ernet.in,"Systemic infection in the mouse model did not depend on yjiY, as the presence of flagella is dispensable for systemic infection by Salmonella in the mouse model.",P Garai 2015,2015,3 genes,Garai-2015-Peptide utilizing carbon starvation,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10326,PHI:7575,UniProt,Q8ZJY5,GenBank,AAL23350,,,LT2; SGSC 1412; ATCC 700720,yjiY,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,peptide-utilizing carbon starvation protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26497384,PubMed,10.1099/mic.0.000204,Microbiology. 2015 Oct 22,dipa@mcbl.iisc.ernet.in,"Systemic infection in the mouse model did not depend on yjiY, as the presence of flagella is dispensable for systemic infection by Salmonella in the mouse model.",P Garai 2015,2015,3 genes,Garai-2015-Peptide utilizing carbon starvation,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10327,PHI:7575,UniProt,Q8ZJY5,GenBank,AAL23350,,,LT2; SGSC 1412; ATCC 700720,yjiY,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,intestine,peptide-utilizing carbon starvation protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26497384,PubMed,10.1099/mic.0.000204,Microbiology. 2015 Oct 22,dipa@mcbl.iisc.ernet.in,"Systemic infection in the mouse model did not depend on yjiY, as the presence of flagella is dispensable for systemic infection by Salmonella in the mouse model.",P Garai 2015,2015,3 genes,Garai-2015-Peptide utilizing carbon starvation,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10328,PHI:7577,UniProt,Q8ZR28,GenBank,AAL19551,,,LT2; SGSC 1412; ATCC 700720,cstA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,intestine,peptide-utilizing carbon starvation protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,26497384,PubMed,10.1099/mic.0.000204,Microbiology. 2015 Oct 22,dipa@mcbl.iisc.ernet.in,"Systemic infection in the mouse model did not depend on yjiY, as the presence of flagella is dispensable for systemic infection by Salmonella in the mouse model.",P Garai 2015,2015,3 genes,Garai-2015-Peptide utilizing carbon starvation,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10329,PHI:7578,UniProt,P9WJG3,GenBank,CCP46406,,,H37Rv,CarD,,CarD127F; CarD127W,,,,,1773,Mycobacterium tuberculosis,652616,Erdman,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,RNA polymerase binding transcription factor,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene mutation,,,YVS,27920294,PubMed,10.1128/JB.00698-16,J Bacteriol. 2017 Jan 30;199(4). pii: e00698-16,stallings@wustl.edu,It was shown that increasing the affinity of CarD for RNAP reduced M. tuberculosis virulence in a mouse model of infection despite the improved growth rate in vitro.,A L Garner 2016,2016,1 gene,Garner-2016-Effects of Increasing the Affinity,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10330,PHI:7579,UniProt,G8BJ61,GenBank,CCE44676,,,CDC317,CPAR2_404800 (CpALS7),,,,,,,5480,Candida parapsilosis,,CBS 604,mycosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,congo red; calcofluor white; fluconazole; caffeine,"congo red: CHEBI:34653; calcofluor white: CHEBI:50011; fluconazole: CHEBI:46081, CAS:86386-73-4; caffeine: CHEBI:27732",,,,,gene disruption; gene complementation,,,YVS,26632333,PubMed,10.1080/21505594.2015.1112491,Virulence. 2016;7(2):85-97,arianna.tavanti@unipi.it,"When compared for adhesion to abiotic surface, CPAR2_404800 null mutants exhibited amarked reduction in their adhesion to buccal epithelial cells.",A Bertini 2015,2015,1 gene,Bertini-2015-Targeted gene disruption in Candi,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10331,PHI:7579,UniProt,G8BJ61,GenBank,CCE44676,,,CDC317,CPAR2_404800 (CpALS7),,,,,,,5480,Candida parapsilosis,,CBS 604,mycosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; bladder,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,congo red; calcofluor white; fluconazole; caffeine,"congo red: CHEBI:34653; calcofluor white: CHEBI:50011; fluconazole: CHEBI:46081, CAS:86386-73-4; caffeine: CHEBI:27732",,,,,gene disruption; gene complementation,,,YVS,26632333,PubMed,10.1080/21505594.2015.1112491,Virulence. 2016;7(2):85-97,arianna.tavanti@unipi.it,"When compared for adhesion to abiotic surface, CPAR2_404800 null mutants exhibited amarked reduction in their adhesion to buccal epithelial cells.",A Bertini 2015,2015,1 gene,Bertini-2015-Targeted gene disruption in Candi,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10332,PHI:7580,UniProt,P9WHW9,GenBank,CCP46702,,,H37Rv,Rv3873 (PPE68),,,,Rv2626c; Rv0462; Rv0652; Rv1093; Rv1388; Rv1837c; Rv2220,UniProt: P9WJA3; GenBank: CCP45424; UniProt: P9WHH9; GenBank: CCP43195; UniProt: P9WHE3; Gen,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,PPE family immunomodulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,26605666,PubMed,10.1080/21505594.2015.1102832,Virulence. 2016;7(1):23-32,lia.danelishvili@oregonstate.edu,"In vitro studies revealed no differences between Mtb parental strain and Rv2626c knockout clone growth within human macrophages; however, the Rv2626c knockout clone showed significantly lower levels of cell necrosis evident at 5 days post-infection.",L Danelishvili 2015,2015,8 genes,Danelishvili-2015-Mycobacterium tuberculosis P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10333,PHI:7581,UniProt,P9WJA3,GenBank,CCP45424,,,H37Rv,Rv2626c,,,,Rv3873,UniProt: P9WHW9; GenBank: CCP46702,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,hypoxic response protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,26605666,PubMed,10.1080/21505594.2015.1102832,Virulence. 2016;7(1):23-32,lia.danelishvili@oregonstate.edu,"In vitro studies revealed no differences between Mtb parental strain and Rv2626c knockout clone growth within human macrophages; however, the Rv2626c knockout clone showed significantly lower levels of cell necrosis evident at 5 days post-infection.",L Danelishvili 2015,2015,8 genes,Danelishvili-2015-Mycobacterium tuberculosis P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10334,PHI:7582,UniProt,P9WHH9,GenBank,CCP43195,,,H37Rv,Rv0462 (lpdC),,,,Rv3873,UniProt: P9WHW9; GenBank: CCP46702,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,dihydrolipoamide dehydrogenase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,26605666,PubMed,10.1080/21505594.2015.1102832,Virulence. 2016;7(1):23-32,lia.danelishvili@oregonstate.edu,"In vitro studies revealed no differences between Mtb parental strain and Rv2626c knockout clone growth within human macrophages; however, the Rv2626c knockout clone showed significantly lower levels of cell necrosis evident at 5 days post-infection.",L Danelishvili 2015,2015,8 genes,Danelishvili-2015-Mycobacterium tuberculosis P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10335,PHI:7583,UniProt,P9WHE3,GenBank,CCP43395,,,H37Rv,Rv0652 (rplL),,,,Rv3873,UniProt: P9WHW9; GenBank: CCP46702,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,50S ribosomal protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,26605666,PubMed,10.1080/21505594.2015.1102832,Virulence. 2016;7(1):23-32,lia.danelishvili@oregonstate.edu,"In vitro studies revealed no differences between Mtb parental strain and Rv2626c knockout clone growth within human macrophages; however, the Rv2626c knockout clone showed significantly lower levels of cell necrosis evident at 5 days post-infection.",L Danelishvili 2015,2015,8 genes,Danelishvili-2015-Mycobacterium tuberculosis P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10336,PHI:7584,UniProt,P9WGI9,GenBank,CCP43846,,,H37Rv,Rv1093 (glyA1),,,,Rv3873,UniProt: P9WHW9; GenBank: CCP46702,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,serine hydroxymethyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,26605666,PubMed,10.1080/21505594.2015.1102832,Virulence. 2016;7(1):23-32,lia.danelishvili@oregonstate.edu,"In vitro studies revealed no differences between Mtb parental strain and Rv2626c knockout clone growth within human macrophages; however, the Rv2626c knockout clone showed significantly lower levels of cell necrosis evident at 5 days post-infection.",L Danelishvili 2015,2015,8 genes,Danelishvili-2015-Mycobacterium tuberculosis P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10337,PHI:7585,UniProt,P71658,GenBank,CCP44147,,,H37Rv,Rv1388 (mihF),,,,Rv3873,UniProt: P9WHW9; GenBank: CCP46702,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,putative integration host factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,26605666,PubMed,10.1080/21505594.2015.1102832,Virulence. 2016;7(1):23-32,lia.danelishvili@oregonstate.edu,"In vitro studies revealed no differences between Mtb parental strain and Rv2626c knockout clone growth within human macrophages; however, the Rv2626c knockout clone showed significantly lower levels of cell necrosis evident at 5 days post-infection.",L Danelishvili 2015,2015,8 genes,Danelishvili-2015-Mycobacterium tuberculosis P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10338,PHI:7586,UniProt,P9WK17,GenBank,CCP44603,,,H37Rv,Rv1837c (glcB),,,,Rv3873,UniProt: P9WHW9; GenBank: CCP46702,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,malate synthase G,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,26605666,PubMed,10.1080/21505594.2015.1102832,Virulence. 2016;7(1):23-32,lia.danelishvili@oregonstate.edu,"In vitro studies revealed no differences between Mtb parental strain and Rv2626c knockout clone growth within human macrophages; however, the Rv2626c knockout clone showed significantly lower levels of cell necrosis evident at 5 days post-infection.",L Danelishvili 2015,2015,8 genes,Danelishvili-2015-Mycobacterium tuberculosis P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10339,PHI:7587,UniProt,P9WN39,GenBank,CCP44998,,,H37Rv,Rv2220 (glnA1),,,,Rv3873,UniProt: P9WHW9; GenBank: CCP46702,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,glutamine synthetase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,26605666,PubMed,10.1080/21505594.2015.1102832,Virulence. 2016;7(1):23-32,lia.danelishvili@oregonstate.edu,"In vitro studies revealed no differences between Mtb parental strain and Rv2626c knockout clone growth within human macrophages; however, the Rv2626c knockout clone showed significantly lower levels of cell necrosis evident at 5 days post-infection.",L Danelishvili 2015,2015,8 genes,Danelishvili-2015-Mycobacterium tuberculosis P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10340,PHI:7581,UniProt,P9WJA3,GenBank,CCP45424,,,H37Rv,Rv2626c,,,,Rv3873,UniProt: P9WHW9; GenBank: CCP46702,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,hypoxic response protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,26605666,PubMed,10.1080/21505594.2015.1102832,Virulence. 2016;7(1):23-32,lia.danelishvili@oregonstate.edu,"In vitro studies revealed no differences between Mtb parental strain and Rv2626c knockout clone growth within human macrophages; however, the Rv2626c knockout clone showed significantly lower levels of cell necrosis evident at 5 days post-infection.",L Danelishvili 2015,2015,8 genes,Danelishvili-2015-Mycobacterium tuberculosis P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10341,PHI:7588,UniProt,A0A0D2Y8P9,GenBank,KNB12966,,,4287,Foatg8,chromosome 9,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici strain H1-ChFP,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,ubiquitin-like protein conjugated to PE involved in phagophore expansion,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25560310,PubMed,10.4161/15548627.2014.994413,Autophagy. 2015;11(1):131-44,ge2rurom@uco.es,Autophagy is required for virulence of F. oxysporum on plant and animal hosts.,C Corral-Ramos 2015,2015,1 gene,Corral-Ramos-2015-Autophagy contributes to reg,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10342,PHI:7588,UniProt,A0A0D2Y8P9,GenBank,KNB12966,,,4287,Foatg8,chromosome 9,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici strain H1-ChFP,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ubiquitin-like protein conjugated to PE involved in phagophore expansion,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25560310,PubMed,10.4161/15548627.2014.994413,Autophagy. 2015;11(1):131-44,ge2rurom@uco.es,Autophagy is required for virulence of F. oxysporum on plant and animal hosts.,C Corral-Ramos 2015,2015,1 gene,Corral-Ramos-2015-Autophagy contributes to reg,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10343,PHI:7589,UniProt,A0A0H2XGW3,GenBank,ABD21090,,,USA300_FPR3757,ctpA,,,,,,,1280,Staphylococcus aureus,,USA300 HOU,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,brain; heart; lung; liver; kidney; spleen,lone S41 family C-terminal processing protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,24928312,PubMed,10.1099/mic.0.079798-0,Microbiology. 2014 Aug;160(Pt 8):1737-48,shaw@usf.edu,Disruption of the ctpA gene led to decreased heat tolerance and increased sensitivity when exposed to components of the host immune system.,R K Carroll 2014,2014,1 gene,Carroll-2014-The lone S41 family C-terminal pr,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10344,PHI:7589,UniProt,A0A0H2XGW3,GenBank,ABD21090,,,USA300_FPR3757,ctpA,,,,,,,1280,Staphylococcus aureus,,USA300 HOU,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,lone S41 family C-terminal processing protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,24928312,PubMed,10.1099/mic.0.079798-0,Microbiology. 2014 Aug;160(Pt 8):1737-48,shaw@usf.edu,Disruption of the ctpA gene led to decreased heat tolerance and increased sensitivity when exposed to components of the host immune system.,R K Carroll 2014,2014,1 gene,Carroll-2014-The lone S41 family C-terminal pr,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10345,PHI:7590,UniProt,B0YAC2,GenBank,EDP48965,,,A1163,erg25A,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,C4-sterol methyl oxidase,,,canonical ergosterol biosynthesis,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; paraquat; ferrous sulfate; fluconazole; voriconazole; amphotericin B; dithiothreitol,"calcofluor white: CHEBI:50011; paraquat: CHEBI:34905; ferrous sulfate: CHEBI:75832; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; dithiothreitol: CHEBI:42170",,,,,gene deletion: full; gene complementation,,,YVS,25107308,PubMed,10.1099/mic.0.080440-0,Microbiology. 2014 Nov;160(Pt 11):2492-506,Robert.a.cramer.jr@dartmouth.edu,"A Δerg25A strain displayed moderate susceptibility to hypoxia and the endoplasmic reticulum stress-inducing agent DTT, but was not required for virulence in murine or insect models of invasive aspergillosis.",S J Blosser 2014,2014,2 genes,Blosser-2014-Two C4-Sterol Methyl Oxidases (Er,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10346,PHI:7591,UniProt,B0YE73,GenBank,EDP47217,,,A1163,erg25B,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,C4-sterol methyl oxidase,,,canonical ergosterol biosynthesis,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; paraquat; ferrous sulfate; fluconazole; voriconazole; amphotericin B; dithiothreitol,"calcofluor white: CHEBI:50011; paraquat: CHEBI:34905; ferrous sulfate: CHEBI:75832; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; dithiothreitol: CHEBI:42170",,,,,gene deletion: full; gene complementation,,,YVS,25107308,PubMed,10.1099/mic.0.080440-0,Microbiology. 2014 Nov;160(Pt 11):2492-506,Robert.a.cramer.jr@dartmouth.edu,"A Δerg25A strain displayed moderate susceptibility to hypoxia and the endoplasmic reticulum stress-inducing agent DTT, but was not required for virulence in murine or insect models of invasive aspergillosis.",S J Blosser 2014,2014,2 genes,Blosser-2014-Two C4-Sterol Methyl Oxidases (Er,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10347,PHI:7590,UniProt,B0YAC2,GenBank,EDP48965,,,A1163,erg25A,,,,,,PHI:7591,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,C4-sterol methyl oxidase,,,canonical ergosterol biosynthesis,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; paraquat; ferrous sulfate; fluconazole; voriconazole; amphotericin B; dithiothreitol,"calcofluor white: CHEBI:50011; paraquat: CHEBI:34905; ferrous sulfate: CHEBI:75832; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; dithiothreitol: CHEBI:42170",,,,,gene deletion: full; gene complementation,,,YVS,25107308,PubMed,10.1099/mic.0.080440-0,Microbiology. 2014 Nov;160(Pt 11):2492-506,Robert.a.cramer.jr@dartmouth.edu,"A Δerg25A strain displayed moderate susceptibility to hypoxia and the endoplasmic reticulum stress-inducing agent DTT, but was not required for virulence in murine or insect models of invasive aspergillosis.",S J Blosser 2014,2014,2 genes,Blosser-2014-Two C4-Sterol Methyl Oxidases (Er,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10348,PHI:7591,UniProt,B0YE73,GenBank,EDP47217,,,A1163,erg25B,,,,,,PHI:7590,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,C4-sterol methyl oxidase,,,canonical ergosterol biosynthesis,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; paraquat; ferrous sulfate; fluconazole; voriconazole; amphotericin B; dithiothreitol,"calcofluor white: CHEBI:50011; paraquat: CHEBI:34905; ferrous sulfate: CHEBI:75832; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; dithiothreitol: CHEBI:42170",,,,,gene deletion: full; gene complementation,,,YVS,25107308,PubMed,10.1099/mic.0.080440-0,Microbiology. 2014 Nov;160(Pt 11):2492-506,Robert.a.cramer.jr@dartmouth.edu,"A Δerg25A strain displayed moderate susceptibility to hypoxia and the endoplasmic reticulum stress-inducing agent DTT, but was not required for virulence in murine or insect models of invasive aspergillosis.",S J Blosser 2014,2014,2 genes,Blosser-2014-Two C4-Sterol Methyl Oxidases (Er,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10349,PHI:7590,UniProt,B0YAC2,GenBank,EDP48965,,,A1163,erg25A,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,larva,C4-sterol methyl oxidase,,,canonical ergosterol biosynthesis,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; paraquat; ferrous sulfate; fluconazole; voriconazole; amphotericin B; dithiothreitol,"calcofluor white: CHEBI:50011; paraquat: CHEBI:34905; ferrous sulfate: CHEBI:75832; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; dithiothreitol: CHEBI:42170",,,,,gene deletion: full; gene complementation,,,YVS,25107308,PubMed,10.1099/mic.0.080440-0,Microbiology. 2014 Nov;160(Pt 11):2492-506,Robert.a.cramer.jr@dartmouth.edu,"A Δerg25A strain displayed moderate susceptibility to hypoxia and the endoplasmic reticulum stress-inducing agent DTT, but was not required for virulence in murine or insect models of invasive aspergillosis.",S J Blosser 2014,2014,2 genes,Blosser-2014-Two C4-Sterol Methyl Oxidases (Er,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10350,PHI:7592,UniProt,Q6NIN5,GenBank,CAE49255,,,NCTC13129,DIP0733,,,,,,,1717,Corynebacterium diphtheriae,698965,CDC-E8392,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,virulence related non-fimbrial surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,25635272,PubMed,10.1099/mic.0.000020,Microbiology. 2015 Mar;161(Pt 3):639-47,andreas.burkovski@fau.de,The mutant showed an altered adhesion pattern and a drastically reduced ability to adhere and invade epithelial cells.,C A Antunes 2015,2015,1 gene,"Antunes-2015-Characterization of DIP0733, a mu",BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10351,PHI:7592,UniProt,Q6NIN5,GenBank,CAE49255,,,NCTC13129,DIP0733,,,,,,,1717,Corynebacterium diphtheriae,698965,CDC-E8392,diphtheria,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,virulence related non-fimbrial surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,25635272,PubMed,10.1099/mic.0.000020,Microbiology. 2015 Mar;161(Pt 3):639-47,andreas.burkovski@fau.de,The mutant showed an altered adhesion pattern and a drastically reduced ability to adhere and invade epithelial cells.,C A Antunes 2015,2015,1 gene,"Antunes-2015-Characterization of DIP0733, a mu",BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10352,PHI:7593,UniProt,J4WD57,GenBank,EJP67980,,,ARSEF 2860,VVD,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,blue-light photoreceptor,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28967173,PubMed,10.1111/1462-2920.13951,Environ Microbiol. 2017 Oct 2,mgfeng@zju.edu.cn,The drastic delay of the lethal action in Δvvd through either normal or cuticle-bypassing infection indicated an essential role of VVD not only in the infection of host by B. bassiana through cuticular penetration but also in the development of the fungal infection after entry into the host hemocoel.,S M Tong 2017,2017,1 gene,Tong-2017-Daylight length-dependent translocat,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10353,PHI:7594,UniProt,A6SR05,GenBank,XP_001546261,,,B05.10,BcCFEM1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),N9059,,,leaf,putative secretory protein,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,NaCl; sorbitol; H2O2; Congo red; SDS; calcofluor white,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,28979251,PubMed,10.3389/fmicb.2017.01807,Front Microbiol. 2017 Sep 20;8:1807,82862108@qq.com,"Targeted deletion of BcCFEM1 in B. cinerea affected virulence, conidial production and stress tolerance, but not growth rate, conidial germination, colony morphology and sclerotial formation.",W Zhu 2017,2017,1 gene,"Zhu-2017-BcCFEM1, a CFEM Domain-Containing Pro",BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10354,PHI:7594,UniProt,A6SR05,GenBank,XP_001546261,,,B05.10,BcCFEM1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),N9059,,,leaf,putative secretory protein,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,NaCl; sorbitol; H2O2; Congo red; SDS; calcofluor white,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white: CHEBI:50011,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28979251,PubMed,10.3389/fmicb.2017.01807,Front Microbiol. 2017 Sep 20;8:1807,82862108@qq.com,"Targeted deletion of BcCFEM1 in B. cinerea affected virulence, conidial production and stress tolerance, but not growth rate, conidial germination, colony morphology and sclerotial formation.",W Zhu 2017,2017,1 gene,"Zhu-2017-BcCFEM1, a CFEM Domain-Containing Pro",BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10355,PHI:7595,UniProt,C8UF66,GenBank,BAI37388,,,11128,EtrA,,,,,,,562,Escherichia coli,,APCE94,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),,,,liver; spleen; lung,type III secretion system 2 regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28895515,PubMed,10.1099/mic.0.000525,Microbiology. 2017 Oct;163(10):1515-1524,yus@shvri.ac.cn,"EtrA gene deletion significantly reduced bacterial survival in macrophages, and proliferation and virulence in ducks.",S Wang 2017,2017,1 gene,Wang-2017-Escherichia coli type III secretion,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10356,PHI:7596,UniProt,I6PDX4,GenBank,AFH78146,,,CQMa102,MakatG1,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,nymph,catalase-peroxidase,,,,reduced virulence,,yes,yes,,,,,wild type,wild type,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,28925548,PubMed,10.1111/1462-2920.13932,Environ Microbiol. 2017 Oct;19(10):4365-4378,yueqingcao@cqu.edu.cn,"Insect bioassays revealed significantly reduced virulence of the ΔMakatG1 mutant when topically inoculated, but no impairment when the insectcuticle was bypassed. Tissue tested fifth instar nymph cuticle",G Li 2017,2017,1 gene,"Li-2017-A bifunctional catalase-peroxidase, Ma",BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10357,PHI:7596,UniProt,I6PDX4,GenBank,AFH78146,,,CQMa102,MakatG1,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,hemocoel,catalase-peroxidase,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,28925548,PubMed,10.1111/1462-2920.13932,Environ Microbiol. 2017 Oct;19(10):4365-4378,yueqingcao@cqu.edu.cn,"Insect bioassays revealed significantly reduced virulence of the ΔMakatG1 mutant when topically inoculated, but no impairment when the insectcuticle was bypassed.",G Li 2017,2017,1 gene,"Li-2017-A bifunctional catalase-peroxidase, Ma",BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10358,PHI:7597,UniProt,W7MCU7,GenBank,EWG49353,,,7600,FvDim5,chromosome 5,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,stem; kernel,lysine histone methyltransferase,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; sorbitol,NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,28957455,PubMed,10.1093/femsle/fnx184,FEMS Microbiol Lett. 2017 Oct 16;364(19),gaoxw@njau.edu.cn,It was found that deletion of FvDIM5 resulted in increased tolerance to osmotic stresses and upregulated FvHog1 phosphorylation.,Q Gu 2017,2017,1 gene,Gu-2017-Histone H3 lysine 9 methyltransferase,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10359,PHI:7598,UniProt,A0A0H2UQ73,GenBank,AAK75339,,,TIGR4; ATCC BAA-334,niaX,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; blood,NAD salvage pathway importer,,,NAD salvage pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26311256,PubMed,10.1099/mic.0.000164,Microbiology. 2015 Nov;161(11):2127-36,jason.rosch@stjude.org,PnuC is critical for lung colonization and bacterial virulence in mice whereas NiaX is dispensable.,M D Johnson 2015,2015,2 genes,Johnson-2015-Characterization of NAD Salvage P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10360,PHI:7599,UniProt,A0A0H2URH5,GenBank,AAK75931,,,TIGR4; ATCC BAA-334,pnuC,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; blood,NAD salvage pathway importer,,,NAD salvage pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26311256,PubMed,10.1099/mic.0.000164,Microbiology. 2015 Nov;161(11):2127-36,jason.rosch@stjude.org,PnuC is critical for lung colonization and bacterial virulence in mice whereas NiaX is dispensable.,M D Johnson 2015,2015,2 genes,Johnson-2015-Characterization of NAD Salvage P,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10361,PHI:7600,UniProt,A0A0H3PB79,GenBank,EAQ73146,,,81-176,CmeB,,81-176/cmeB::kan r,,,,,197,Campylobacter jejuni,,81-176,gastroenteritis,eukaryotes,5757,Acanthamoeba polyphaga (no common name found),Linc Ap-1,,,,RND-type efflux pump membrane transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,YVS,28916560,PubMed,10.1128/AEM.01600-17,Appl Environ Microbiol. 2017 Sep 15. pii: AEM.01600-17,a.karlyshev@kingston.ac.uk,"MDR pump was beneficial for the intracellular survival and multiplication of C. jejuni in A. polyphaga, but was dispensable for biofilm formation and motility.",A Vieira 2017,2017,1 gene,Vieira-2017-CmeABC multidrug efflux pump contr,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10362,PHI:7601,UniProt,Q7DB85,GenBank,AE005594_9,,,EDL933,EspF,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28983470,PubMed,10.3389/fcimb.2017.00410,Front Cell Infect Microbiol. 2017 Sep 21;7:410,gzwcs@smu.edu.cn,The N-terminal domain of the Enterohemorrhagic E. coli O157:H7 EspF more strongly promotes apoptosis and inflammation than the C-terminal domain.,X Wang 2017,2017,1 gene,Wang-2017-The EspF N-Terminal of Enterohemorrh,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10363,PHI:7601,UniProt,Q7DB85,GenBank,AE005594_9,,,EDL933,EspF,,ΔespFN,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,28983470,PubMed,10.3389/fcimb.2017.00410,Front Cell Infect Microbiol. 2017 Sep 21;7:410,gzwcs@smu.edu.cn,The N-terminal domain of the Enterohemorrhagic E. coli O157:H7 EspF more strongly promotes apoptosis and inflammation than the C-terminal domain.,X Wang 2017,2017,1 gene,Wang-2017-The EspF N-Terminal of Enterohemorrh,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10364,PHI:7601,UniProt,Q7DB85,GenBank,AE005594_9,,,EDL933,EspF,,ΔespFC,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,28983470,PubMed,10.3389/fcimb.2017.00410,Front Cell Infect Microbiol. 2017 Sep 21;7:410,gzwcs@smu.edu.cn,The N-terminal domain of the Enterohemorrhagic E. coli O157:H7 EspF more strongly promotes apoptosis and inflammation than the C-terminal domain.,X Wang 2017,2017,1 gene,Wang-2017-The EspF N-Terminal of Enterohemorrh,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10365,PHI:7602,UniProt,O42720,GenBank,EEH05536,,,G186AR,cbp1,,,,,,,5037,Histoplasma capsulatum,,G217B ura5Δ,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,secreted protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28953979,PubMed,10.1371/journal.ppat.1006589,PLoS Pathog. 2017 Sep 27;13(9):e1006589,sil@cgl.ucsf.edu,"Host gene alteration data available for CHOP and TRIB3. Strains bearing a non-lytic allele of CBP1 (D58A) failed to activate integrated stress response (ISR), whereas a partially lytic CBP1 allele (D10A) triggerd intermediate levels of activation and the macrophages deficient for CHOP or TRIB3 were partially resistant to lysis during Hc infection, indicating that the ISR was critical for susceptibility to Hc-mediated cell death.",B C English 2017,2017,1 gene,"English-2017-The transcription factor CHOP, an",BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10366,PHI:7602,UniProt,O42720,GenBank,EEH05536,,,G186AR,cbp1,,D10A; D58A,,,,,5037,Histoplasma capsulatum,,G217B ura5Δ,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,secreted protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28953979,PubMed,10.1371/journal.ppat.1006589,PLoS Pathog. 2017 Sep 27;13(9):e1006589,sil@cgl.ucsf.edu,"Host gene alteration data available for CHOP and TRIB3. Strains bearing a non-lytic allele of CBP1 (D58A) failed to activate integrated stress response (ISR), whereas a partially lytic CBP1 allele (D10A) triggerd intermediate levels of activation and the macrophages deficient for CHOP or TRIB3 were partially resistant to lysis during Hc infection, indicating that the ISR was critical for susceptibility to Hc-mediated cell death.",B C English 2017,2017,1 gene,"English-2017-The transcription factor CHOP, an",BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10367,PHI:7603,UniProt,Q57EK6,GenBank,AAX73928,,,9-941,rfbE,chromosome I,,,,,,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,O-antigen export system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10368,PHI:7603,UniProt,Q57EK6,GenBank,AAX73928,,,9-941,rfbE,chromosome I,,,,,PHI:7604; PHI:7605; PHI:7606,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,O-antigen export system ATP-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10369,PHI:7604,UniProt,Q2YIT5,GenBank,AF226278_1,,,2308,virB1,,,,,,PHI:7603; PHI:7605; PHI:7606,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,type IV secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10370,PHI:7605,UniProt,Q2YIT6,GenBank,AF226278_2,,,2308,virB2,,,,,,PHI:7603; PHI:7604; PHI:7606,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,type IV secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10371,PHI:7606,UniProt,Q2YIT7,GenBank,AF226278_3,,,2308,virB3,,,,,,PHI:7603; PHI:7604; PHI:7605,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,type IV secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10372,PHI:7603,UniProt,Q57EK6,GenBank,AAX73928,,,9-941,rfbE,chromosome I,,,,,PHI:7607,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,O-antigen export system ATP-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10373,PHI:7607,UniProt,Q2YJ50,GenBank,CAJ12284,,,2308,vjbR,chromosome II,,,,,PHI:7603,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,HTH-type quorum sensing-dependent transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10374,PHI:7603,UniProt,Q57EK6,GenBank,AAX73928,,,9-941,rfbE,chromosome I,,,,,PHI:7608,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,O-antigen export system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10375,PHI:7608,,no data found,,,,,,MdrA,,,,,,PHI:7603,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,MarR-like sodium deoxycholate-responsive activator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10376,PHI:7603,UniProt,Q57EK6,GenBank,AAX73928,,,9-941,rfbE,chromosome I,,,,,PHI:7609,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,O-antigen export system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10377,PHI:7609,UniProt,Q2YP49,GenBank,CAJ10146,,,2308,BlxR,chromosome I,,,,,PHI:7603,235,Brucella abortus,,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,quorum sensing-related regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29021973,PubMed,10.3389/fcimb.2017.00422,Front Cell Infect Microbiol. 2017 Sep 27;7:422,yus@shvri.ac.cn,Deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression.,P Li 2017,2017,7 genes,Li-2017-Brucella Rough Mutant Induce Macrophag,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10378,PHI:7610,UniProt,B5LBI1,GenBank,ACH56227,,,,cathepsin S (Rs-cps),,,,,,,46012,Radopholus similis,,,blackhead toppling disease,eudicots,4100,Nicotiana benthamiana (no common name found),,,,root,cysteine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29030572,PubMed,10.1038/s41598-017-13024-9,Sci Rep. 2017 Oct 13;7(1):13126,sbj8624@sina.com,Rs-cps transgenic N. benthamiana plants were resistant to R. similis and the reproduction and hatching rate of R. similis isolated from the Rs-cps transgenic plants were also significantly reduced.,Y Li 2017,2017,1 gene,Li-2017-Transgenic Nicotiana benthamiana plant,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10379,PHI:7611,UniProt,P52698,GenBank,CAD16455,,,GMI1000,phcA,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,root,LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28951474,PubMed,10.1128/mBio.00895-17,MBio. 2017 Sep 26;8(5). pii: e00895-17,callen@wisc.edu,"PhcA helped R. solanacearum to survive in nutrient-poor environmental habitats and to grow rapidly during early pathogenesis, however, after R. solanacearum reached high cell densities in planta, PhcA mediated a trade-off from maximizing growth to producing costly virulence factors.",D Khokhani 2017,2017,1 gene,Khokhani-2017-A Single Regulator Mediates Stra,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10380,PHI:7612,,no data found,,,,,,cpaA,,,,cpaB,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,metallopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28982978,PubMed,10.1074/jbc.M117.808394,J Biol Chem. 2017 Oct 5. pii: jbc.M117.808394,mariofeldman@wustl.edu,The virulence defects resulting from the deletion of cpaA are comparable to those observed upon abrogation of T2SS activity.,R L Kinsella 2017,2017,2 genes,Kinsella-2017-Defining the interaction of the,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10381,PHI:7613,UniProt,A0A2T7FJE6,GenBank,OUJ94081,,,CAS04,gspD,,,,,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,outer membrane secretin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28982978,PubMed,10.1074/jbc.M117.808394,J Biol Chem. 2017 Oct 5. pii: jbc.M117.808394,mariofeldman@wustl.edu,The virulence defects resulting from the deletion of cpaA are comparable to those observed upon abrogation of T2SS activity.,R L Kinsella 2017,2017,2 genes,Kinsella-2017-Defining the interaction of the,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10382,PHI:7612,,no data found,,,,,,cpaA,,,,cpaB,,,106654,Acinetobacter nosocomialis,1343071,M2,bacteremia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,lung; spleen,metallopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28982978,PubMed,10.1074/jbc.M117.808394,J Biol Chem. 2017 Oct 5. pii: jbc.M117.808394,mariofeldman@wustl.edu,The virulence defects resulting from the deletion of cpaA were comparable to those observed upon abrogation of T2SS activity.,R L Kinsella 2017,2017,2 genes,Kinsella-2017-Defining the interaction of the,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10383,PHI:7614,UniProt,Q54913,GenBank,CAA56616,,,CS101,orf-1,,,,,,,1314,Streptococcus pyogenes,530008,serotype M3 strain MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,hypothetical protein,,,RopB-SIP signaling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28923955,PubMed,10.1073/pnas.1705972114,Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8498-E8507,mkumaraswami@houstonmethodist.org,SIP signaling pathway was active during infection and contributed significantly to GAS pathogenesis at multiple host anatomic sites.,H Do 2017,2017,3 genes,Do-2017-Leaderless secreted peptide signaling,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10384,PHI:7615,UniProt,A0A0K0P1E4,GenBank,AKP99533,,,2000V1019P,ropB,,,,,,,1314,Streptococcus pyogenes,530008,serotype M3 strain MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,transcriptional regulator of protease B,,,RopB-SIP signaling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28923955,PubMed,10.1073/pnas.1705972114,Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8498-E8507,mkumaraswami@houstonmethodist.org,SIP signaling pathway was active during infection and contributed significantly to GAS pathogenesis at multiple host anatomic sites.,H Do 2017,2017,3 genes,Do-2017-Leaderless secreted peptide signaling,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10385,PHI:7616,UniProt,A0A0H3C0P3,GenBank,ACI61943,,,NZ131; ATCC BAA-1633,speB,,,,,,,1314,Streptococcus pyogenes,530008,serotype M3 strain MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,secreted cysteine protease,,,RopB-SIP signaling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28923955,PubMed,10.1073/pnas.1705972114,Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8498-E8507,mkumaraswami@houstonmethodist.org,SIP signaling pathway was active during infection and contributed significantly to GAS pathogenesis at multiple host anatomic sites.,H Do 2017,2017,3 genes,Do-2017-Leaderless secreted peptide signaling,BATCH_074A,2017-10-01,MC,,,,,,,,,,,,,
,,Record 10386,PHI:7617,UniProt,Q8Y6G5,GenBank,CAC99800,,,EGD-e,Lmo1722,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,DExD-box RNA-helicase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25590644,PubMed,10.1080/15476286.2014.996099,RNA Biol. 2014;11(11):1457-66,karolis.vaitkevicius@molbiol.umu.se,"Although the expression of the PrfA regulated virulence factors ActA and LLO decreased in the quadruple mutant strain, this strain showed a slightly increased infection ability. Epithelial colorectal adenocarcinoma cells",C Bareclev 2015,2015,4 genes,Bareclev-2015-DExD-box RNA-helicases in Lister,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10387,PHI:7618,UniProt,Q8Y7M8,GenBank,CAC99324,,,EGD-e,Lmo1246,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,DExD-box RNA-helicase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25590644,PubMed,10.1080/15476286.2014.996099,RNA Biol. 2014;11(11):1457-66,karolis.vaitkevicius@molbiol.umu.se,"Although the expression of the PrfA regulated virulence factors ActA and LLO decreased in the quadruple mutant strain, this strain showed a slightly increased infection ability. Epithelial colorectal adenocarcinoma cells",C Bareclev 2015,2015,4 genes,Bareclev-2015-DExD-box RNA-helicases in Lister,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10388,PHI:7619,UniProt,Q8Y755,GenBank,CAC99528,,,EGD-e,Lmo1450,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,DExD-box RNA-helicase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25590644,PubMed,10.1080/15476286.2014.996099,RNA Biol. 2014;11(11):1457-66,karolis.vaitkevicius@molbiol.umu.se,"Although the expression of the PrfA regulated virulence factors ActA and LLO decreased in the quadruple mutant strain, this strain showed a slightly increased infection ability. Epithelial colorectal adenocarcinoma cells",C Bareclev 2015,2015,4 genes,Bareclev-2015-DExD-box RNA-helicases in Lister,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10389,PHI:7620,UniProt,Q8Y8N0,GenBank,CAC98944,,,EGD-e,Lmo0866,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,DExD-box RNA-helicase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25590644,PubMed,10.1080/15476286.2014.996099,RNA Biol. 2014;11(11):1457-66,karolis.vaitkevicius@molbiol.umu.se,"Although the expression of the PrfA regulated virulence factors ActA and LLO decreased in the quadruple mutant strain, this strain showed a slightly increased infection ability. Epithelial colorectal adenocarcinoma cells",C Bareclev 2015,2015,4 genes,Bareclev-2015-DExD-box RNA-helicases in Lister,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10390,PHI:7617,UniProt,Q8Y6G5,GenBank,CAC99800,,,EGD-e,Lmo1722,,,,,,PHI:7618; PHI:7619; PHI:7620,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,DExD-box RNA-helicase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,25590644,PubMed,10.1080/15476286.2014.996099,RNA Biol. 2014;11(11):1457-66,karolis.vaitkevicius@molbiol.umu.se,"Although the expression of the PrfA regulated virulence factors ActA and LLO decreased in the quadruple mutant strain, this strain showed a slightly increased infection ability. Epithelial colorectal adenocarcinoma cells",C Bareclev 2015,2015,4 genes,Bareclev-2015-DExD-box RNA-helicases in Lister,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10391,PHI:7618,UniProt,Q8Y7M8,GenBank,CAC99324,,,EGD-e,Lmo1246,,,,,,PHI:7617; PHI:7619; PHI:7620,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,DExD-box RNA-helicase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,25590644,PubMed,10.1080/15476286.2014.996099,RNA Biol. 2014;11(11):1457-66,karolis.vaitkevicius@molbiol.umu.se,"Although the expression of the PrfA regulated virulence factors ActA and LLO decreased in the quadruple mutant strain, this strain showed a slightly increased infection ability. Epithelial colorectal adenocarcinoma cells",C Bareclev 2015,2015,4 genes,Bareclev-2015-DExD-box RNA-helicases in Lister,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10392,PHI:7619,UniProt,Q8Y755,GenBank,CAC99528,,,EGD-e,Lmo1450,,,,,,PHI:7617; PHI:7618; PHI:7620,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,DExD-box RNA-helicase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,25590644,PubMed,10.1080/15476286.2014.996099,RNA Biol. 2014;11(11):1457-66,karolis.vaitkevicius@molbiol.umu.se,"Although the expression of the PrfA regulated virulence factors ActA and LLO decreased in the quadruple mutant strain, this strain showed a slightly increased infection ability. Epithelial colorectal adenocarcinoma cells",C Bareclev 2015,2015,4 genes,Bareclev-2015-DExD-box RNA-helicases in Lister,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10393,PHI:7620,UniProt,Q8Y8N0,GenBank,CAC98944,,,EGD-e,Lmo0866,,,,,,PHI:7617; PHI:7618; PHI:7619,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,DExD-box RNA-helicase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,25590644,PubMed,10.1080/15476286.2014.996099,RNA Biol. 2014;11(11):1457-66,karolis.vaitkevicius@molbiol.umu.se,"Although the expression of the PrfA regulated virulence factors ActA and LLO decreased in the quadruple mutant strain, this strain showed a slightly increased infection ability. Epithelial colorectal adenocarcinoma cells",C Bareclev 2015,2015,4 genes,Bareclev-2015-DExD-box RNA-helicases in Lister,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10394,PHI:7621,,no data found,,,,,,ExpI,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10395,PHI:7621,,no data found,,,,,,ExpI,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10396,PHI:7621,,no data found,,,,,,ExpI,,,,,,,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10397,PHI:7621,,no data found,,,,,,ExpI,,,,,,,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10398,PHI:7621,,no data found,,,,,,ExpI,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10399,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10400,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10401,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10402,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10403,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10404,PHI:7623,,no data found,,,,,,vfmA,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10405,PHI:7623,,no data found,,,,,,vfmA,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10406,PHI:7623,,no data found,,,,,,vfmA,,,,,,,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10407,PHI:7623,,no data found,,,,,,vfmA,,,,,,,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10408,PHI:7623,,no data found,,,,,,vfmA,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10409,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10410,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10411,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10412,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10413,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10414,PHI:7625,,no data found,,,,,,vfmH,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10415,PHI:7625,,no data found,,,,,,vfmH,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10416,PHI:7625,,no data found,,,,,,vfmH,,,,,,,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10417,PHI:7625,,no data found,,,,,,vfmH,,,,,,,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10418,PHI:7625,,no data found,,,,,,vfmH,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10419,PHI:7626,,no data found,,,,,,vfmI,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10420,PHI:7626,,no data found,,,,,,vfmI,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10421,PHI:7626,,no data found,,,,,,vfmI,,,,,,,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10422,PHI:7626,,no data found,,,,,,vfmI,,,,,,,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10423,PHI:7626,,no data found,,,,,,vfmI,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10424,PHI:7627,,no data found,,,,,,vfmK,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10425,PHI:7627,,no data found,,,,,,vfmK,,,,,,,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10426,PHI:7627,,no data found,,,,,,vfmK,,,,,,,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10427,PHI:7627,,no data found,,,,,,vfmK,,,,,,,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10428,PHI:7627,,no data found,,,,,,vfmK,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10429,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10430,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10431,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10432,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10433,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10434,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10435,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10436,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10437,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10438,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10439,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10440,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10441,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10442,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10443,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10444,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10445,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10446,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10447,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10448,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10449,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10450,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10451,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10452,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10453,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10454,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10455,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10456,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10457,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10458,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10459,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10460,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10461,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10462,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10463,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10464,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10465,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0123,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10466,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0158,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10467,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0221,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10468,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate chicory leaves in Figure 1. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10469,PHI:7621,,no data found,,,,,,ExpI,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10470,PHI:7621,,no data found,,,,,,ExpI,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10471,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10472,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10473,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10474,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10475,PHI:7626,,no data found,,,,,,vfmI,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10476,PHI:7626,,no data found,,,,,,vfmI,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10477,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10478,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10479,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10480,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10481,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10482,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10483,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7621,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10484,PHI:7621,,no data found,,,,,,ExpI,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10485,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10486,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10487,PHI:7626,,no data found,,,,,,vfmI,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10488,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7626,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10489,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10490,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10491,PHI:7624,UniProt,U6ZIB1,GenBank,ERO59133,,,D s0432-1,vfmE,,,,,,PHI:7622,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10492,PHI:7622,UniProt,U6ZIC9,GenBank,ERO59153,,,D s0432-1,ExpR,,,,,,PHI:7624,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28921772,PubMed,10.1111/mpp.12614,Mol Plant Pathol.2017 Sep 18,marta.potrykus@biotech.ug.edu.pl,Phenotype was assigned based on D. solani mutants ability to macerate potato tuber tissue in Table 2. Data also available for production of plant cell wall degrading enzymes (PCWDE) and motility.,M Potrykus 2017,2017,7 genes,Potrykus-2017-Interplay of classic Exp and spe,BATCH_074B,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10493,PHI:7628,UniProt,A0A125YYK6,GenBank,EPT30740,,,ME49,TgIST,chromosome VI,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27414498,PubMed,10.1016/j.chom.2016.06.006,Cell Host Microbe.2016 Jul 13;20(1):72-82,sibley@wustl.edu,"The decreased virulence of the TgIST knockout was restored in IFN-γ-receptor 1 deficient mice (Ifngr1-/-), indicating it was not intrinsically impaired in vivo.",P Olias 2016,2016,1 gene,Olias-2016-Toxoplasma Effector Recruits the Mi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10494,PHI:7629,UniProt,E9DSK0,GenBank,EFY93360,,,CQMa 102,MaSte12,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,nymph,Ste12-like transcription factor,,,,reduced virulence,,yes,,,,wild type,,wild type,reduced,no,calcofluor white; Congo red; NaCl; SDS; sorbitol; H2O2,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; NaCl: CHEBI:26710; SDS: CHEBI:8984; sorbitol: CHEBI:17924; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29079863,PubMed,10.1007/s00253-017-8569-x,Appl Microbiol Biotechnol.2017 Oct 28,yuxianxia@cqu.edu.cn,MaSte12 is involved in fungal virulence but not conidial yield or fungal stress tolerance in M. acridum. fifth instar nymphs,Q Wei 2017,2017,1 gene,Wei-2017-The Ste12-like transcription factor M,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10495,PHI:7630,UniProt,Q9HVW7,GenBank,AAG07838,,,PAO1,murA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,lung,UDP-N-acetylglucosamine 1-carboxyvinyltransferase,,,cell wall biosynthesis,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10496,PHI:7631,UniProt,Q9HVZ9,GenBank,AE004856_13,,,PAO1,murD,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,lung,UDP-N-acetylmuramoylalanine--D-glutamate ligase,,,cell wall biosynthesis,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10497,PHI:7632,UniProt,Q9HVZ7,GenBank,AAG07804,,,PAO1,murF,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,lung,peptidyl-prolyl cis-trans isomerase,,,cell wall biosynthesis,unaffected pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10498,PHI:7633,UniProt,Q9I2U9,GenBank,AE004605_4,,,PAO1,ppiB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,lung,peptidyl-prolyl cis-trans isomerase,,,cell wall biosynthesis,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10499,PHI:7634,UniProt,Q9HU22,GenBank,AE004929_3,,,PAO1,rmlA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,lung,glucose-1-phosphate thymidylyltransferase,,,cell wall biosynthesis,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10500,PHI:7635,UniProt,Q9HUH7,GenBank,AE004911_8,,,PAO1,waaA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,lung,3-deoxy-D-manno-octulosonic-acid (KDO) transferase,,,cell wall biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10501,PHI:7630,UniProt,Q9HVW7,GenBank,AAG07838,,,PAO1,murA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,UDP-N-acetylglucosamine 1-carboxyvinyltransferase,,,cell wall biosynthesis,unaffected pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10502,PHI:7631,UniProt,Q9HVZ9,GenBank,AE004856_13,,,PAO1,murD,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,UDP-N-acetylmuramoylalanine--D-glutamate ligase,,,cell wall biosynthesis,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10503,PHI:7632,UniProt,Q9HVZ7,GenBank,AAG07804,,,PAO1,murF,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,peptidyl-prolyl cis-trans isomerase,,,cell wall biosynthesis,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10504,PHI:7633,UniProt,Q9I2U9,GenBank,AE004605_4,,,PAO1,ppiB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,peptidyl-prolyl cis-trans isomerase,,,cell wall biosynthesis,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10505,PHI:7634,UniProt,Q9HU22,GenBank,AE004929_3,,,PAO1,rmlA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,glucose-1-phosphate thymidylyltransferase,,,cell wall biosynthesis,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10506,PHI:7635,UniProt,Q9HUH7,GenBank,AE004911_8,,,PAO1,waaA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,3-deoxy-D-manno-octulosonic-acid (KDO) transferase,,,cell wall biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29045498,PubMed,10.1371/journal.pone.0186801,PLoS One.2017 Oct 18;12(10):e0186801,info@lionex.de,"In macrophage-mediated bactericidal assay, deletion of cell wall biosynthesis genes resulted in a significantly decreased survival of the bacteria.",A A Elamin 2017,2017,6 genes,Elamin-2017-Novel drug targets in cell wall bi,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10507,PHI:7636,UniProt,A0A0D2XPQ9,GenBank,KNB03469,,,4287,PARG,chromosome 2a,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,poly(ADP-ribose) glycohydrolase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,28956188,PubMed,10.1007/s10482-017-0951-2,Antonie Van Leeuwenhoek.2017 Sep 27,bfranco@ugto.mx,PARG protein of F. oxysporum f. sp. lycopersici is involved in DNA repair and does not act in pathogenicity as an effector.,C A Araiza-Cervantes 2017,2017,1 gene,Araiza-Cervante-2017-Biochemical and genetic a,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10508,PHI:7636,UniProt,A0A0D2XPQ9,GenBank,KNB03469,,,4287,PARG,chromosome 2a,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,poly(ADP-ribose) glycohydrolase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,28956188,PubMed,10.1007/s10482-017-0951-2,Antonie Van Leeuwenhoek.2017 Sep 27,bfranco@ugto.mx,PARG protein of F. oxysporum f. sp. lycopersici is involved in DNA repair and does not act in pathogenicity as an effector.,C A Araiza-Cervantes 2017,2017,1 gene,Araiza-Cervante-2017-Biochemical and genetic a,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10509,PHI:7637,UniProt,P0A355,GenBank,CAA62903,,,ATCC 23074,CspA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10510,PHI:7638,UniProt,P0A357,GenBank,CAD00094,,,EGD-e,CspB,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10511,PHI:7639,UniProt,Q92AD0,GenBank,CAC99957,,,EGD-e,CspD,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10512,PHI:7637,UniProt,P0A355,GenBank,CAA62903,,,ATCC 23074,CspA,,,,,,PHI:7638,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10513,PHI:7638,UniProt,P0A357,GenBank,CAD00094,,,EGD-e,CspB,,,,,,PHI:7637,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10514,PHI:7637,UniProt,P0A355,GenBank,CAA62903,,,ATCC 23074,CspA,,,,,,PHI:7639,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10515,PHI:7639,UniProt,Q92AD0,GenBank,CAC99957,,,EGD-e,CspD,,,,,,PHI:7637,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10516,PHI:7638,UniProt,P0A357,GenBank,CAD00094,,,EGD-e,CspB,,,,,,PHI:7639,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10517,PHI:7639,UniProt,Q92AD0,GenBank,CAC99957,,,EGD-e,CspD,,,,,,PHI:7638,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10518,PHI:7637,UniProt,P0A355,GenBank,CAA62903,,,ATCC 23074,CspA,,,,,,PHI:7638; PHI:7639,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10519,PHI:7638,UniProt,P0A357,GenBank,CAD00094,,,EGD-e,CspB,,,,,,PHI:7637; PHI:7639,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10520,PHI:7639,UniProt,Q92AD0,GenBank,CAC99957,,,EGD-e,CspD,,,,,,PHI:7637; PHI:7638,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10521,PHI:7637,UniProt,P0A355,GenBank,CAA62903,,,ATCC 23074,CspA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10522,PHI:7638,UniProt,P0A357,GenBank,CAD00094,,,EGD-e,CspB,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10523,PHI:7639,UniProt,Q92AD0,GenBank,CAC99957,,,EGD-e,CspD,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10524,PHI:7637,UniProt,P0A355,GenBank,CAA62903,,,ATCC 23074,CspA,,,,,,PHI:7638,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10525,PHI:7638,UniProt,P0A357,GenBank,CAD00094,,,EGD-e,CspB,,,,,,PHI:7637,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10526,PHI:7637,UniProt,P0A355,GenBank,CAA62903,,,ATCC 23074,CspA,,,,,,PHI:7639,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10527,PHI:7639,UniProt,Q92AD0,GenBank,CAC99957,,,EGD-e,CspD,,,,,,PHI:7637,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10528,PHI:7638,UniProt,P0A357,GenBank,CAD00094,,,EGD-e,CspB,,,,,,PHI:7639,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10529,PHI:7639,UniProt,Q92AD0,GenBank,CAC99957,,,EGD-e,CspD,,,,,,PHI:7638,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10530,PHI:7637,UniProt,P0A355,GenBank,CAA62903,,,ATCC 23074,CspA,,,,,,PHI:7638; PHI:7639,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10531,PHI:7638,UniProt,P0A357,GenBank,CAD00094,,,EGD-e,CspB,,,,,,PHI:7637; PHI:7639,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10532,PHI:7639,UniProt,Q92AD0,GenBank,CAC99957,,,EGD-e,CspD,,,,,,PHI:7637; PHI:7638,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29124040,PubMed,10.3389/fcimb.2017.00453,Front Cell Infect Microbiol.2017 Oct 26;7:453,tasarat@fsafety.uzh.ch,"An evaluation of double csp gene deletion mutant (ΔcspBD, ΔcspAD and ΔcspAB) strains that produce single csp genes showed that there is redundancy as well as functional differences among the three L.monocytogenes Csps in their contributions to virulence, cellular aggregation, flagella production and swarming motility.",A K Eshwar 2017,2017,3 genes,Eshwar-2017-Cold-Shock Domain Family Proteins,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10533,PHI:7640,UniProt,Q9KTU5,GenBank,AAF93957,,,N16961,oadB,chromosome I,,,,,,666,Vibrio cholerae,,PSU 966,cholera,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,oxaloacetate decarboxylase beta subunit,,,,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene mutation; chemical complementation,,,YVS,27407302,PubMed,10.1007/s12088-016-0592-6,Indian J Microbiol.2016 Sep;56(3):368-74,varaporn.v@psu.ac.th,"Thus, accumulation of Na+ ions in an oxaloacetate decarboxylase mutant of V. cholerae could be the plausible mechanism behind indole negative phenotype and virulence reduction in the V. cholerae mutant.",T Nuidate 2016,2016,1 gene,Nuidate-2016-Role of Indole Production on Viru,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10534,PHI:7641,,no data found,,,,,,Pmc1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,H+/Ca2+ exchanger protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29113016,PubMed,10.1111/cmi.12803,Cell Microbiol.2017 Nov 7,liviak@cbiot.ufrgs.br,The complete absence of pmc1 mutant infection in the brain in the mouse model was the impaired ability of this mutant to transmigrate through the blood brain barrier and to survive within the brain parenchyma.,E D Squizani 2017,2017,2 genes,Squizani-2017-Cryptococcal dissemination to th,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10535,PHI:7642,,no data found,,,,,,Vcx1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,Ca2+-ATPase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29113016,PubMed,10.1111/cmi.12803,Cell Microbiol.2017 Nov 7,liviak@cbiot.ufrgs.br,The complete absence of pmc1 mutant infection in the brain in the mouse model was the impaired ability of this mutant to transmigrate through the blood brain barrier and to survive within the brain parenchyma.,E D Squizani 2017,2017,2 genes,Squizani-2017-Cryptococcal dissemination to th,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10536,PHI:7641,,no data found,,,,,,Pmc1,,,,,,PHI:7642,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,H+/Ca2+ exchanger protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29113016,PubMed,10.1111/cmi.12803,Cell Microbiol.2017 Nov 7,liviak@cbiot.ufrgs.br,The complete absence of pmc1 mutant infection in the brain in the mouse model was the impaired ability of this mutant to transmigrate through the blood brain barrier and to survive within the brain parenchyma.,E D Squizani 2017,2017,2 genes,Squizani-2017-Cryptococcal dissemination to th,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10537,PHI:7642,,no data found,,,,,,Vcx1,,,,,,PHI:7641,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,Ca2+-ATPase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29113016,PubMed,10.1111/cmi.12803,Cell Microbiol.2017 Nov 7,liviak@cbiot.ufrgs.br,The complete absence of pmc1 mutant infection in the brain in the mouse model was the impaired ability of this mutant to transmigrate through the blood brain barrier and to survive within the brain parenchyma.,E D Squizani 2017,2017,2 genes,Squizani-2017-Cryptococcal dissemination to th,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10538,PHI:7643,UniProt,P0AA34,GenBank,AAL20878,,,LT2; SGSC 1412; ATCC 700720,yedF,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,cervical adenocarcinoma cell line,hypothetical transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29127378,PubMed,10.1038/s41598-017-15369-7,Sci Rep.2017 Nov 10;7(1):15291,anna.fabrega@vhir.org,For STM1441 and yedF a reduced ability to interact with HeLa cells was observed in the knock-out mutants.,C Ballesté-Delpierre 2017,2017,1 gene,Balleste-Delpie-2017-First insights into the p,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10539,PHI:7644,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ece1,chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,"candidalysin, a short, amphipathic pore-forming peptide",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29101209,PubMed,10.1126/sciimmunol.aam8834,Sci Immunol.2017 Nov 3;2(17). pii: eaam8834,julian.naglik@kcl.ac.uk,Candidalysin-deficient strains of C. albicans caused minimal epithelial damage and elicited a blunted type 17 immune response.,A H Verma 2017,2017,1 gene,Verma-2017-Oral epithelial cells orchestrate i,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10540,PHI:7645,UniProt,A0A0H2XCS3,GenBank,AAY51279,,,8004,XccbphP,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,bacteriophytochrome photoreceptor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27621284,PubMed,10.15252/embr.201541691,EMBO Rep.2016 Nov;17(11):1565-1577,hbonomi@leloir.org.ar,The capacity of XccBphP to respond to light both in vitro and in vivo was abolished by a mutation on the conserved Cys13 residue.,H R Bonomi 2016,2016,1 gene,Bonomi-2016-Xanthomonas campestris attenuates,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10541,PHI:7646,UniProt,P0ACR9,GenBank,CAA38090,,,K-12,mprA,,,,,,,562,Escherichia coli,,PA45B,urinary tract infection,primates,9606,Homo sapiens (related: human),,,,blood,transcriptional repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29066548,PubMed,10.1128/mBio.01558-17,MBio.2017 Oct 24;8(5). pii: e01558-17,m.schembri@uq.edu.au,Loss of MprA or overexpression of LrhA affected the transcription of capsule biosynthesis genes in PA45B and increased sensitivity to killing in whole blood.,K G K Goh 2017,2017,2 genes,Goh-2017-Genome-Wide Discovery of Genes Requir,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10542,PHI:7647,UniProt,P36771,GenBank,CAA52637,,,K-12,LrhA,,,,,,,562,Escherichia coli,,PA45B,urinary tract infection,primates,9606,Homo sapiens (related: human),,,,blood,probable HTH-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29066548,PubMed,10.1128/mBio.01558-17,MBio.2017 Oct 24;8(5). pii: e01558-17,m.schembri@uq.edu.au,Loss of MprA or overexpression of LrhA affected the transcription of capsule biosynthesis genes in PA45B and increased sensitivity to killing in whole blood.,K G K Goh 2017,2017,2 genes,Goh-2017-Genome-Wide Discovery of Genes Requir,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10543,PHI:7648,UniProt,I1RAN7,GenBank,CEF72524,,,PH-1,FgPR-IL-1,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Wheaton,,,spikelet,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29117786,PubMed,10.1094/PHYTO-08-17-0268-R,Phytopathology.2017 Nov 8,Shunwen.Lu@ars.usda.gov,Virulence phenotypes of the wild type isolate of Fusarium graminearum and the FgPR-1L-4 deletion mutants on resistant wheat showed that none of the treatments caused bleached spikelets on Sumai 3 (resistant) cultivar that were observed on susceptible wheat under the same conditions.,S Lu 2017,2017,4 genes,Lu-2017-Molecular Characterization and Functio,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10544,PHI:7649,UniProt,I1RG88,GenBank,CEF75101,,,PH-1,FgPR-IL-2,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Wheaton,,,spikelet,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29117786,PubMed,10.1094/PHYTO-08-17-0268-R,Phytopathology.2017 Nov 8,Shunwen.Lu@ars.usda.gov,Virulence phenotypes of the wild type isolate of Fusarium graminearum and the FgPR-1L-4 deletion mutants on resistant wheat showed that none of the treatments caused bleached spikelets on Sumai 3 (resistant) cultivar that were observed on susceptible wheat under the same conditions.,S Lu 2017,2017,4 genes,Lu-2017-Molecular Characterization and Functio,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10545,PHI:7650,UniProt,I1RH65,GenBank,CEF77846,,,PH-1,FgPR-IL-3,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Wheaton,,,spikelet,uncharacterized protein,,,,unaffected pathogenicity,yes,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29117786,PubMed,10.1094/PHYTO-08-17-0268-R,Phytopathology.2017 Nov 8,Shunwen.Lu@ars.usda.gov,Virulence phenotypes of the wild type isolate of Fusarium graminearum and the FgPR-1L-4 deletion mutants on resistant wheat showed that none of the treatments caused bleached spikelets on Sumai 3 (resistant) cultivar that were observed on susceptible wheat under the same conditions.,S Lu 2017,2017,4 genes,Lu-2017-Molecular Characterization and Functio,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10546,PHI:7651,UniProt,I1RHQ1,GenBank,CEF78090,,,PH-1,FgPR-IL-4,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Wheaton,,,spikelet,uncharacterized protein,,,,reduced virulence,no,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29117786,PubMed,10.1094/PHYTO-08-17-0268-R,Phytopathology.2017 Nov 8,Shunwen.Lu@ars.usda.gov,Virulence phenotypes of the wild type isolate of Fusarium graminearum and the FgPR-1L-4 deletion mutants on resistant wheat showed that none of the treatments caused bleached spikelets on Sumai 3 (resistant) cultivar that were observed on susceptible wheat under the same conditions.,S Lu 2017,2017,4 genes,Lu-2017-Molecular Characterization and Functio,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10547,PHI:7652,UniProt,Q4WVS3,GenBank,EAL91303,,,Af293,aroC,chromosome 5,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,chorismate mutase,,,aromatic amino acid biosynthesis pathway,reduced virulence,,,,,,,,reduced,reduced,no,carbonyl cyanide m-chlorophenyl hydrazone; sodium azide,carbonyl cyanide m-chlorophenyl hydrazone: CHEBI:3259; sodium azide: CHEBI:278547,,,,,gene deletion: full; gene complementation,,,YVS,26605426,PubMed,10.1080/21505594.2015.1109766,Virulence.2016;7(1):56-62,sven.krappmann@uk-erlangen.de,"The essentiality of the complete biosynthetic pathway was demonstrated, corroborated by conditional gene expression in infected animals and inhibitor studies.",A Sasse 2015,2015,3 genes,Sasse-2015-Mutant Characterisation and In Vivo,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10548,PHI:7653,UniProt,Q4WLR6,GenBank,EAL89098,,,Af293,trpA,chromosome 6,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,anthranilate synthase component I,,,,reduced virulence,,,,,,,,reduced,,no,carbonyl cyanide m-chlorophenyl hydrazone; sodium azide,carbonyl cyanide m-chlorophenyl hydrazone: CHEBI:3259; sodium azide: CHEBI:278547,,,,,gene deletion: full; gene complementation,,,YVS,26605426,PubMed,10.1080/21505594.2015.1109766,Virulence.2016;7(1):56-62,sven.krappmann@uk-erlangen.de,"The essentiality of the complete biosynthetic pathway was demonstrated, corroborated by conditional gene expression in infected animals and inhibitor studies.",A Sasse 2015,2015,3 genes,Sasse-2015-Mutant Characterisation and In Vivo,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10549,PHI:7654,UniProt,Q4WJ77,GenBank,EAL88405,,,Af293,aroB,chromosome 1,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,chorismate synthase,,,,reduced virulence,,,,,,,,,,no,carbonyl cyanide m-chlorophenyl hydrazone; sodium azide,carbonyl cyanide m-chlorophenyl hydrazone: CHEBI:3259; sodium azide: CHEBI:278547,,,,,gene deletion: full; gene complementation,,,YVS,26605426,PubMed,10.1080/21505594.2015.1109766,Virulence.2016;7(1):56-62,sven.krappmann@uk-erlangen.de,"The essentiality of the complete biosynthetic pathway was demonstrated, corroborated by conditional gene expression in infected animals and inhibitor studies.",A Sasse 2015,2015,3 genes,Sasse-2015-Mutant Characterisation and In Vivo,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10550,PHI:7655,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,PHI:7656,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,transcriptional activator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,29089927,PubMed,10.3389/fmicb.2017.01944,Front Microbiol.2017 Oct 17;8:1944,yujialin468@163.com,"P. aeruginosa lasR rhlR mutant has weaker biofilm formation and reduced virulence factor production as compared with PAO1, however, the addition of AI-2 to P. aeruginosa lasR rhlR mutant cultures resulted in no significant changes as compared to P. aeruginosa lasR rhlR mutant group.",H Li 2017,2017,2 genes,Li-2017-Autoinducer-2 Facilitates Pseudomonas,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10551,PHI:7656,UniProt,P54292,GenBank,AAC44036,,,PAO1,rhlR,chromosome 1,,,,,PHI:7655,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,regulatory protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,29089927,PubMed,10.3389/fmicb.2017.01944,Front Microbiol.2017 Oct 17;8:1944,yujialin468@163.com,"P. aeruginosa lasR rhlR mutant has weaker biofilm formation and reduced virulence factor production as compared with PAO1, however, the addition of AI-2 to P. aeruginosa lasR rhlR mutant cultures resulted in no significant changes as compared to P. aeruginosa lasR rhlR mutant group.",H Li 2017,2017,2 genes,Li-2017-Autoinducer-2 Facilitates Pseudomonas,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10552,PHI:7657,UniProt,A0A0F6B1X1,GenBank,ACY88508,,,14028S,pspA,,ΔpspABCD::Cm (Cmr),,,,PHI:7658; PHI:7659; PHI:7660,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10553,PHI:7658,UniProt,A0A0F6B1X0,GenBank,ACY88507,,,14028S,pspB,,ΔpspABCD::Cm (Cmr),,,,PHI:7657; PHI:7659; PHI:7660,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10554,PHI:7659,UniProt,A0A0F6B1W9,GenBank,ACY88506,,,14028S,pspC,,ΔpspABCD::Cm (Cmr),,,,PHI:7657; PHI:7658; PHI:7660,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10555,PHI:7660,UniProt,A0A0F6B1W8,GenBank,ACY88505,,,14028S,pspD,,ΔpspABCD::Cm (Cmr),,,,PHI:7657; PHI:7658; PHI:7659,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10556,PHI:7657,UniProt,A0A0F6B1X1,GenBank,ACY88508,,,14028S,pspA,,ΔpspA::Kan (kanr),,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10557,PHI:7658,UniProt,A0A0F6B1X0,GenBank,ACY88507,,,14028S,pspB,,"ΔpspB::Kan+pINS06 (kanr, ampr)",,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10558,PHI:7659,UniProt,A0A0F6B1W9,GenBank,ACY88506,,,14028S,pspC,,ΔpspC::Kan (kanr),,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,spleen,phage-shock protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10559,PHI:7660,UniProt,A0A0F6B1W8,GenBank,ACY88505,,,14028S,pspD,,ΔpspD::Kan (kanr),,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,spleen,phage-shock protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10560,PHI:7661,UniProt,A0A0F6BA89,GenBank,ACY91441,,,14028S,pspG,,ΔpspG::Kan (kanr),,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,spleen,phage-shock protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10561,PHI:7657,UniProt,A0A0F6B1X1,GenBank,ACY88508,,,14028S,pspA,,ΔpspABCD::Cm (Cmr),,,,PHI:7658; PHI:7659; PHI:7660,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (NRAMP1-),,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10562,PHI:7658,UniProt,A0A0F6B1X0,GenBank,ACY88507,,,14028S,pspB,,ΔpspABCD::Cm (Cmr),,,,PHI:7657; PHI:7659; PHI:7660,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (NRAMP1-),,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10563,PHI:7659,UniProt,A0A0F6B1W9,GenBank,ACY88506,,,14028S,pspC,,ΔpspABCD::Cm (Cmr),,,,PHI:7657; PHI:7658; PHI:7660,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (NRAMP1-),,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10564,PHI:7660,UniProt,A0A0F6B1W8,GenBank,ACY88505,,,14028S,pspD,,ΔpspABCD::Cm (Cmr),,,,PHI:7657; PHI:7658; PHI:7659,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (NRAMP1-),,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10565,PHI:7657,UniProt,A0A0F6B1X1,GenBank,ACY88508,,,14028S,pspA,,ΔpspA::Kan (kanr),,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (NRAMP1-),,,spleen,phage-shock protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10566,PHI:7658,UniProt,A0A0F6B1X0,GenBank,ACY88507,,,14028S,pspB,,"ΔpspB::Kan+pINS06 (kanr, ampr)",,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (NRAMP1-),,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10567,PHI:7659,UniProt,A0A0F6B1W9,GenBank,ACY88506,,,14028S,pspC,,ΔpspC::Kan (kanr),,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (NRAMP1-),,,spleen,phage-shock protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10568,PHI:7660,UniProt,A0A0F6B1W8,GenBank,ACY88505,,,14028S,pspD,,ΔpspD::Kan (kanr),,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (NRAMP1-),,,spleen,phage-shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10569,PHI:7661,UniProt,A0A0F6BA89,GenBank,ACY91441,,,14028S,pspG,,ΔpspG::Kan (kanr),,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (NRAMP1-),,,spleen,phage-shock protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,24713356,PubMed,10.1099/jmm.0.072223-0,J Med Microbiol.2014 Jun;63(Pt 6):788-95,jeo@sund.ku.dk,"Removal of PspB reduces virulence in S. Typhimurium independently of host NRAMP1 expression, demonstrating that PspB has roles in intra-host survival distinct from the reported contributions of PspA.",I Wallrodt 2014,2014,5 genes,Wallrodt-2014-Removal of the Phage Shock Prote,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10570,PHI:7662,UniProt,P08870,GenBank,AAL22592,,,LT2; SGSC 1412; ATCC 700720,pyrE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA431,salmonellosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,cecum; tonsil; spleen; liver; bursa of Fabricius,orotate phosphoribosyltransferase,,,de novo pyrimidine biosynthetic pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; chemical complementation,,,YVS,29040285,PubMed,10.1371/journal.pone.0183751,PLoS One.2017 Oct 17;12(10):e0183751,handrews@medicine.tamhsc.edu,"Colonization defect of a pyrE mutant during infection occured in chicks, but not in CBA/J mice or ligated ileal loops in calves, and the uracil supplementation restored the ability of the pyrE mutant to colonize chicks.",H J Yang 2017,2017,1 gene,Yang-2017-De novo pyrimidine synthesis is nece,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10571,PHI:7662,UniProt,P08870,GenBank,AAL22592,,,LT2; SGSC 1412; ATCC 700720,pyrE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA431,salmonellosis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,cecum; Peyer's gland; mesenteric lymph node; spleen; liver,orotate phosphoribosyltransferase,,,de novo pyrimidine biosynthetic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; chemical complementation,,,YVS,29040285,PubMed,10.1371/journal.pone.0183751,PLoS One.2017 Oct 17;12(10):e0183751,handrews@medicine.tamhsc.edu,"Colonization defect of a pyrE mutant during infection occured in chicks, but not in CBA/J mice or ligated ileal loops in calves, and the uracil supplementation restored the ability of the pyrE mutant to colonize chicks.",H J Yang 2017,2017,1 gene,Yang-2017-De novo pyrimidine synthesis is nece,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10572,PHI:7662,UniProt,P08870,GenBank,AAL22592,,,LT2; SGSC 1412; ATCC 700720,pyrE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA431,salmonellosis,even-toed ungulates,9913,Bos taurus (related: cattle),Angus cross,,,ileum,orotate phosphoribosyltransferase,,,de novo pyrimidine biosynthetic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; chemical complementation,,,YVS,29040285,PubMed,10.1371/journal.pone.0183751,PLoS One.2017 Oct 17;12(10):e0183751,handrews@medicine.tamhsc.edu,"Colonization defect of a pyrE mutant during infection occured in chicks, but not in CBA/J mice or ligated ileal loops in calves, and the uracil supplementation restored the ability of the pyrE mutant to colonize chicks.",H J Yang 2017,2017,1 gene,Yang-2017-De novo pyrimidine synthesis is nece,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10573,PHI:7663,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney,mitogen-activated protein kinase,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,tunicamycin,tunicamycin: CHEBI:29699,,,,,gene mutation,,,YVS,27191378,PubMed,10.1080/21505594.2016.1163458,Virulence.2016 Jul 3;7(5):558-77,jesuspla@farm.ucm.es,"Mice defective in this lectin were found to be more resistant to fungal infection compared to galectin-3+/+ mice, showing a less pronounced weight loss and in general, less fungal burden on target organs.",E Roman 2016,2016,1 gene,Roman-2016-The Cek1mediated MAP kinase pathway,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10574,PHI:7663,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; brain; liver,mitogen-activated protein kinase,,,,reduced virulence,,,,,,,,,,no,tunicamycin,tunicamycin: CHEBI:29699,,,,,gene mutation,,,YVS,27191378,PubMed,10.1080/21505594.2016.1163458,Virulence.2016 Jul 3;7(5):558-77,jesuspla@farm.ucm.es,"Mice defective in this lectin were found to be more resistant to fungal infection compared to galectin-3+/+ mice, showing a less pronounced weight loss and in general, less fungal burden on target organs.",E Roman 2016,2016,1 gene,Roman-2016-The Cek1mediated MAP kinase pathway,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10575,PHI:7664,UniProt,A0A0A2ILW0,GenBank,KGO57615,,,MD-8,LysM1,,,,,,,27334,Penicillium expansum,,PE100/PEX2,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,LysM effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,29084256,PubMed,10.1371/journal.pone.0186023,PLoS One. 2017 Oct 30;12(10):e0186023,samird@volcani.agri.gov.iI,"PeLysM3 has a potential role in growth processes, howerver, no significant effect of PeLysM1-4 null mutations on the rate of lesion development was observed relative to the ectopic mutants and WT strain.",E Levin 2017,2017,4 genes,Levin-2017-Identification and characterization,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10576,PHI:7665,UniProt,A0A0A2JVC2,GenBank,KGO58766,,,MD-8,LysM2,,,,,,,27334,Penicillium expansum,,PE100/PEX2,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,LysM effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,29084256,PubMed,10.1371/journal.pone.0186023,PLoS One. 2017 Oct 30;12(10):e0186023,samird@volcani.agri.gov.iI,"PeLysM3 has a potential role in growth processes, howerver, no significant effect of PeLysM1-4 null mutations on the rate of lesion development was observed relative to the ectopic mutants and WT strain.",E Levin 2017,2017,4 genes,Levin-2017-Identification and characterization,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10577,PHI:7666,UniProt,A0A0A2JY92,GenBank,KGO59781,,,MD-8,LysM3,,,,,,,27334,Penicillium expansum,,PE100/PEX2,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,LysM effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full,,,YVS,29084256,PubMed,10.1371/journal.pone.0186023,PLoS One. 2017 Oct 30;12(10):e0186023,samird@volcani.agri.gov.iI,"PeLysM3 has a potential role in growth processes, howerver, no significant effect of PeLysM1-4 null mutations on the rate of lesion development was observed relative to the ectopic mutants and WT strain.",E Levin 2017,2017,4 genes,Levin-2017-Identification and characterization,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10578,PHI:7667,UniProt,A0A0A2JB06,GenBank,KGO51991,,,MD-8,LysM4,,,,,,,27334,Penicillium expansum,,PE100/PEX2,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,LysM effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,29084256,PubMed,10.1371/journal.pone.0186023,PLoS One. 2017 Oct 30;12(10):e0186023,samird@volcani.agri.gov.iI,"PeLysM3 has a potential role in growth processes, howerver, no significant effect of PeLysM1-4 null mutations on the rate of lesion development was observed relative to the ectopic mutants and WT strain.",E Levin 2017,2017,4 genes,Levin-2017-Identification and characterization,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10579,PHI:7668,UniProt,A0A059ZQI8,GenBank,AKA32956,,,AB5075-UW,gigA,,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,noncanonical two-component system (TCS) response regulator (RR) harboring a protein phosphatase domain,,,,reduced virulence,,,,,,,,reduced,,no,kanamycin; gentamycin; ZnCl2,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,28264991,PubMed,10.1128/JB.00066-17,J Bacteriol. 2017 Apr 25;199(10). pii: e00066-17,mgebhardt@uchicago.edu,GigA and GigB are required for in vitro stress resistance.,M J Gebhardt 2017,2017,2 genes,Gebhardt-2017-GigA and GigB are Master Regulat,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10580,PHI:7669,UniProt,A0A0D5YL42,GenBank,AKA32957,,,AB5075-UW,gigB,,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,anti-sigma factor antagonist,,,,reduced virulence,,,,,,,,reduced,,no,kanamycin; gentamycin; ZnCl2,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,28264991,PubMed,10.1128/JB.00066-17,J Bacteriol. 2017 Apr 25;199(10). pii: e00066-17,mgebhardt@uchicago.edu,GigA and GigB are required for in vitro stress resistance.,M J Gebhardt 2017,2017,2 genes,Gebhardt-2017-GigA and GigB are Master Regulat,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10581,PHI:7668,UniProt,A0A059ZQI8,GenBank,AKA32956,,,AB5075-UW,gigA,,,,,,PHI:7669,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,noncanonical two-component system (TCS) response regulator (RR) harboring a protein phosphatase domain,,,,reduced virulence,,,,,,,,reduced,,no,kanamycin; gentamycin; ZnCl2,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,28264991,PubMed,10.1128/JB.00066-17,J Bacteriol. 2017 Apr 25;199(10). pii: e00066-17,mgebhardt@uchicago.edu,GigA and GigB are required for in vitro stress resistance.,M J Gebhardt 2017,2017,2 genes,Gebhardt-2017-GigA and GigB are Master Regulat,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10582,PHI:7669,UniProt,A0A0D5YL42,GenBank,AKA32957,,,AB5075-UW,gigB,,,,,,PHI:7668,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,anti-sigma factor antagonist,,,,reduced virulence,,,,,,,,reduced,,no,kanamycin; gentamycin; ZnCl2,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,28264991,PubMed,10.1128/JB.00066-17,J Bacteriol. 2017 Apr 25;199(10). pii: e00066-17,mgebhardt@uchicago.edu,GigA and GigB are required for in vitro stress resistance.,M J Gebhardt 2017,2017,2 genes,Gebhardt-2017-GigA and GigB are Master Regulat,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10583,PHI:7670,UniProt,D0F0C3,GenBank,ACX53639,,,CYR32,PsFUZ7,,,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,yellow rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,mitogen-activated protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29070517,PubMed,10.1104/pp.17.01223,Plant Physiol. 2017 Oct 25. pii: pp.01223.2017,guojunwgq@nwsuaf.edu.cn,"A PsFUZ7 RNAi construct stably expressed in two independent transgenic wheat lines confered strong resistance to Pst, hyphal development was strongly restricted, and necrosis of plant cells in resistance responses was significantly induced.",X Zhu 2017,2017,1 gene,Zhu-2017-Host-induced gene silencing of the MA,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10584,PHI:7671,UniProt,A1JQ74,GenBank,CAL13026,,,8081,ybeY,,,,,,,630,Yersinia enterocolitica,34054,serotype O:3 strain 6471/76,yersiniosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,cervical adenocarcinoma cell line,endoribonuclease,,,,reduced virulence,,,,,,,,reduced,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full; gene complementation,,,YVS,25416689,PubMed,10.1099/mic.0.083097-0,Microbiology. 2015 Feb;161(Pt 2):285-99,mikael.skurnik@helsinki.fi,"HeLa cell infections showed that the inactivation of the ybeY gene decreased the ability of the bacteria to infect the eukaryotic cells, the most severe defect could be seen in adhesion, whereas the ybeY bacteria showed no apparent impairment in invasion of the HeLa cells by the cell-associated bacteria.",K Leskinen 2014,2014,1 gene,Leskinen-2014-The absence of YbeY ribonuclease,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10585,PHI:7672,UniProt,I1RXT3,GenBank,CEF83060,,,PH-1,FgLetm1,chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Wheaton,,,spikelet,mitochondrial membrane protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,NaCl; KCl; iprodione; phenamacril; FeSO4; CaCl2,"NaCl: CHEBI:26710; KCl: CHEBI:32588; iprodione: CHEBI:28909, CAS:36734-19-7; phenamacril: CAS:3336-69-4; FeSO4: CHEBI:75832; CaCl2: CHEBI:3312",,,,,gene deletion: full; gene complementation,,,YVS,29077257,PubMed,10.1111/mpp.12633,Mol Plant Pathol. 2017 Oct 27,chenyun0927@zju.edu.cn,"The FgLetm1 deletion mutant had a vegetative growth defect, abnormal conidia, the mutant was also more sensitive to various stress agents and significantly reduced the levels of cellular ROS, decreased DON biosynthesis and attenuated virulence in planta.",G Tang 2017,2017,2 genes,Tang-2017-The mitochondrial membrane protein F,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10586,PHI:7673,UniProt,I1S047,GenBank,CEF75402,,,PH-1,FgLetm2,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Wheaton,,,spikelet,mitochondrial membrane protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; KCl; iprodione; phenamacril; FeSO4; CaCl2,"NaCl: CHEBI:26710; KCl: CHEBI:32588; iprodione: CHEBI:28909, CAS:36734-19-7; phenamacril: CAS:3336-69-4; FeSO4: CHEBI:75832; CaCl2: CHEBI:3312",,,,,gene deletion: full; gene complementation,,,YVS,29077257,PubMed,10.1111/mpp.12633,Mol Plant Pathol. 2017 Oct 27,chenyun0927@zju.edu.cn,"The FgLetm1 deletion mutant had a vegetative growth defect, abnormal conidia, the mutant was also more sensitive to various stress agents and significantly reduced the levels of cellular ROS, decreased DON biosynthesis and attenuated virulence in planta.",G Tang 2017,2017,2 genes,Tang-2017-The mitochondrial membrane protein F,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10587,PHI:7672,UniProt,I1RXT3,GenBank,CEF83060,,,PH-1,FgLetm1,chromosome 4,,,,,PHI:7673,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Wheaton,,,spikelet,mitochondrial membrane protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,NaCl; KCl; iprodione; phenamacril; FeSO4; CaCl2,"NaCl: CHEBI:26710; KCl: CHEBI:32588; iprodione: CHEBI:28909, CAS:36734-19-7; phenamacril: CAS:3336-69-4; FeSO4: CHEBI:75832; CaCl2: CHEBI:3312",,,,,gene deletion: full; gene complementation,,,YVS,29077257,PubMed,10.1111/mpp.12633,Mol Plant Pathol. 2017 Oct 27,chenyun0927@zju.edu.cn,"The FgLetm1 deletion mutant had a vegetative growth defect, abnormal conidia, the mutant was also more sensitive to various stress agents and significantly reduced the levels of cellular ROS, decreased DON biosynthesis and attenuated virulence in planta.",G Tang 2017,2017,2 genes,Tang-2017-The mitochondrial membrane protein F,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10588,PHI:7673,UniProt,I1S047,GenBank,CEF75402,,,PH-1,FgLetm2,chromosome 1,,,,,PHI:7672,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Wheaton,,,spikelet,mitochondrial membrane protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,NaCl; KCl; iprodione; phenamacril; FeSO4; CaCl2,"NaCl: CHEBI:26710; KCl: CHEBI:32588; iprodione: CHEBI:28909, CAS:36734-19-7; phenamacril: CAS:3336-69-4; FeSO4: CHEBI:75832; CaCl2: CHEBI:3312",,,,,gene deletion: full; gene complementation,,,YVS,29077257,PubMed,10.1111/mpp.12633,Mol Plant Pathol. 2017 Oct 27,chenyun0927@zju.edu.cn,"The FgLetm1 deletion mutant had a vegetative growth defect, abnormal conidia, the mutant was also more sensitive to various stress agents and significantly reduced the levels of cellular ROS, decreased DON biosynthesis and attenuated virulence in planta.",G Tang 2017,2017,2 genes,Tang-2017-The mitochondrial membrane protein F,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10589,PHI:7674,UniProt,Q9Z4N7,GenBank,AAK67274,,,MMH594,Esp,,,,,,,1351,Enterococcus faecalis,1158653,MMH594,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal cavity; liver,enterococcal surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26503704,PubMed,10.1177/1753425915611237,Innate Immun. 2016 Jan;22(1):31-9,nathan-shankar@ouhsc.edu,Neutrophil infiltration and tissue damage in the liver was higher in the mice infected with the Esp-expressing strain compared with mice infected with the Esp-deficient mutant.,J Zou 2015,2015,1 gene,Zou-2015-Surface protein Esp enhances pro-infl,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10590,PHI:7674,UniProt,Q9Z4N7,GenBank,AAK67274,,,MMH594,Esp,,,,,,,1351,Enterococcus faecalis,1158653,MMH594,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,enterococcal surface protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,26503704,PubMed,10.1177/1753425915611237,Innate Immun. 2016 Jan;22(1):31-9,nathan-shankar@ouhsc.edu,Neutrophil infiltration and tissue damage in the liver was higher in the mice infected with the Esp-expressing strain compared with mice infected with the Esp-deficient mutant.,J Zou 2015,2015,1 gene,Zou-2015-Surface protein Esp enhances pro-infl,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10591,PHI:7675,UniProt,M9V3B7,GenBank,AGJ74031,,,ATCC 9545,Plx2A,,,,,,,1464,Paenibacillus larvae,147375,subsp. larvae,American foulbrood,moths,7108,Spodoptera frugiperda (related: Fall armyworm),cv. Sf9,,,,RhoA-targeting ADP-ribosyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29124866,PubMed,10.1111/1462-2920.13989,Environ Microbiol.2017 Nov 10,elke.genersch@fu-berlin.de,"Plx2A was cytotoxic to yeast cells, interfered with actin remodelling in murine macrophages and with cytokinesis in insect cells.",J Ebeling 2017,2017,1 gene,Ebeling-2017-Characterization of the toxin Plx,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10592,PHI:7675,UniProt,M9V3B7,GenBank,AGJ74031,,,ATCC 9545,Plx2A,,,,,,,1464,Paenibacillus larvae,147375,subsp. larvae,American foulbrood,moths,7111,Trichoplusia ni (related: Cabbage looper),BTI-Tn-5B1-4 cell line,,,,RhoA-targeting ADP-ribosyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29124866,PubMed,10.1111/1462-2920.13989,Environ Microbiol.2017 Nov 10,elke.genersch@fu-berlin.de,"Plx2A was cytotoxic to yeast cells, interfered with actin remodelling in murine macrophages and with cytokinesis in insect cells.",J Ebeling 2017,2017,1 gene,Ebeling-2017-Characterization of the toxin Plx,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10593,PHI:7676,UniProt,P62576,GenBank,AAL00340,,,R6,NanA,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung,bacterial sialidase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,27593514,PubMed,10.1016/j.chom.2016.07.019,Cell Host Microbe.2016 Sep 14;20(3):307-317,birgitta.henriques@ki.se,Host gene alteration data available for cytidine-monophosphate-N-acetylneuraminic acid hydroxylase (CMAH). Pneumococcal challenge in Cmah-/- mice leads to heightened bacterial loads and virulence.,K Hentrich 2016,2016,5 genes,Hentrich-2016-Streptococcus pneumoniae Senses,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10594,PHI:7677,UniProt,A0A0H2URD1,GenBank,AAK75762,,,TIGR4; ATCC BAA-334,SatA,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung,substrate binding protein of sialic acid transporter,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,27593514,PubMed,10.1016/j.chom.2016.07.019,Cell Host Microbe.2016 Sep 14;20(3):307-317,birgitta.henriques@ki.se,Host gene alteration data available for cytidine-monophosphate-N-acetylneuraminic acid hydroxylase (CMAH). Pneumococcal challenge in Cmah-/- mice leads to heightened bacterial loads and virulence.,K Hentrich 2016,2016,5 genes,Hentrich-2016-Streptococcus pneumoniae Senses,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10595,PHI:7678,UniProt,A0A0H2URB2,GenBank,AAK75761,,,TIGR4; ATCC BAA-334,SatB,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung,"sialic acid transporter, permease protein",,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,27593514,PubMed,10.1016/j.chom.2016.07.019,Cell Host Microbe.2016 Sep 14;20(3):307-317,birgitta.henriques@ki.se,Host gene alteration data available for cytidine-monophosphate-N-acetylneuraminic acid hydroxylase (CMAH). Pneumococcal challenge in Cmah-/- mice leads to heightened bacterial loads and virulence.,K Hentrich 2016,2016,5 genes,Hentrich-2016-Streptococcus pneumoniae Senses,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10596,PHI:7679,UniProt,A0A0H2UR33,GenBank,AAK75760,,,TIGR4; ATCC BAA-334,SatC,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung,"sialic acid transporter, permease protein",,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,27593514,PubMed,10.1016/j.chom.2016.07.019,Cell Host Microbe.2016 Sep 14;20(3):307-317,birgitta.henriques@ki.se,Host gene alteration data available for cytidine-monophosphate-N-acetylneuraminic acid hydroxylase (CMAH). Pneumococcal challenge in Cmah-/- mice leads to heightened bacterial loads and virulence.,K Hentrich 2016,2016,5 genes,Hentrich-2016-Streptococcus pneumoniae Senses,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10597,PHI:7680,UniProt,P0A4H7,GenBank,AAK74935,,,TIGR4; ATCC BAA-334,CiaR,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung,two-component response regulator,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,27593514,PubMed,10.1016/j.chom.2016.07.019,Cell Host Microbe.2016 Sep 14;20(3):307-317,birgitta.henriques@ki.se,Host gene alteration data available for cytidine-monophosphate-N-acetylneuraminic acid hydroxylase (CMAH). Pneumococcal challenge in Cmah-/- mice leads to heightened bacterial loads and virulence.,K Hentrich 2016,2016,5 genes,Hentrich-2016-Streptococcus pneumoniae Senses,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10598,PHI:7681,UniProt,Q4WTJ9,GenBank,EAL90233,,,Af293,RgsC,chromosome 1,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,regulator of G-protein signaling,,,G protein signaling,reduced virulence,,,,,,reduced,,reduced,aberrant,no,Congo red; calcofluor white; caspofungin; H2O2; menadione; paraquat,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; caspofungin: CHEBI:474180; H2O2: CHEBI:16240; menadione: CHEBI:28869; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29109714,PubMed,10.3389/fmicb.2017.02058,Front Microbiol.2017 Oct 23;8:2058,shinks@dju.kr,"RgsC was shown to be necessary for proper growth, development, stress response, GT production and external nutrients sensing.",Y Kim 2017,2017,1 gene,Kim-2017-Characteristics of a Regulator of G-P,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10599,PHI:7682,UniProt,A0A0C4DHR8,GenBank,KNB00710,,,4287,nit1,chromosome 4,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,nitrate reductase,,,nitrate assimilation pathway,unaffected pathogenicity,,,,,,,,reduced,reduced,no,,,,,,,gene mutation,,,YVS,29043485,PubMed,10.1007/s00294-017-0766-8,Curr Genet.2017 Oct 17,ge1gorom@uco.es,The results indicated that the Nit1 and Ntr1 proteins were important for nitrate assimilation of F. oxysporum f.sp. lycopersici incubated under aerobic and anaerobic conditions and that this metabolic process was not essential for the virulence of the fungus.,L Gomez-Gil 2017,2017,4 genes,Gomez-Gil-2017-Nitrate assimilation pathway (N,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10600,PHI:7683,UniProt,A0A0J9ULI2,GenBank,KNB00115,,,4287,nit2,chromosome 4,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,nitrate reductase,,,nitrate assimilation pathway,unaffected pathogenicity,,,,,,,,wild type,wild type,no,,,,,,,gene mutation,,,YVS,29043485,PubMed,10.1007/s00294-017-0766-8,Curr Genet.2017 Oct 17,ge1gorom@uco.es,The results indicated that the Nit1 and Ntr1 proteins were important for nitrate assimilation of F. oxysporum f.sp. lycopersici incubated under aerobic and anaerobic conditions and that this metabolic process was not essential for the virulence of the fungus.,L Gomez-Gil 2017,2017,4 genes,Gomez-Gil-2017-Nitrate assimilation pathway (N,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10601,PHI:7682,UniProt,A0A0C4DHR8,GenBank,KNB00710,,,4287,nit1,chromosome 4,,,,,PHI:7683,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,nitrate reductase,,,nitrate assimilation pathway,unaffected pathogenicity,,,,,,,,reduced,reduced,no,,,,,,,gene mutation,,,YVS,29043485,PubMed,10.1007/s00294-017-0766-8,Curr Genet.2017 Oct 17,ge1gorom@uco.es,The results indicated that the Nit1 and Ntr1 proteins were important for nitrate assimilation of F. oxysporum f.sp. lycopersici incubated under aerobic and anaerobic conditions and that this metabolic process was not essential for the virulence of the fungus.,L Gomez-Gil 2017,2017,4 genes,Gomez-Gil-2017-Nitrate assimilation pathway (N,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10602,PHI:7683,UniProt,A0A0J9ULI2,GenBank,KNB00115,,,4287,nit2,chromosome 4,,,,,PHI:7682,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,nitrate reductase,,,nitrate assimilation pathway,unaffected pathogenicity,,,,,,,,reduced,reduced,no,,,,,,,gene mutation,,,YVS,29043485,PubMed,10.1007/s00294-017-0766-8,Curr Genet.2017 Oct 17,ge1gorom@uco.es,The results indicated that the Nit1 and Ntr1 proteins were important for nitrate assimilation of F. oxysporum f.sp. lycopersici incubated under aerobic and anaerobic conditions and that this metabolic process was not essential for the virulence of the fungus.,L Gomez-Gil 2017,2017,4 genes,Gomez-Gil-2017-Nitrate assimilation pathway (N,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10603,PHI:7684,UniProt,A0A0D2X9S0,GenBank,KNA94738,,,4287,ntr1,chromosome 1,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,high-affinity nitrate/nitrite transporter,,,nitrate assimilation pathway,increased virulence (hypervirulence),,,,,,,,,reduced,no,,,,,,,gene mutation,,,YVS,29043485,PubMed,10.1007/s00294-017-0766-8,Curr Genet.2017 Oct 17,ge1gorom@uco.es,The results indicated that the Nit1 and Ntr1 proteins were important for nitrate assimilation of F. oxysporum f.sp. lycopersici incubated under aerobic and anaerobic conditions and that this metabolic process was not essential for the virulence of the fungus.,L Gomez-Gil 2017,2017,4 genes,Gomez-Gil-2017-Nitrate assimilation pathway (N,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10604,PHI:7685,UniProt,A0A0J9UIM0,GenBank,KNA99039,,,4287,AreA,chromosome 8,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,leaf,nitrogen status-sensing regulatory protein,,,nitrate assimilation pathway,increased virulence (hypervirulence),,,,,,,,reduced,reduced,no,,,,,,,gene mutation; gene complementation,,,YVS,29043485,PubMed,10.1007/s00294-017-0766-8,Curr Genet.2017 Oct 17,ge1gorom@uco.es,The results indicated that the Nit1 and Ntr1 proteins were important for nitrate assimilation of F. oxysporum f.sp. lycopersici incubated under aerobic and anaerobic conditions and that this metabolic process was not essential for the virulence of the fungus.,L Gomez-Gil 2017,2017,4 genes,Gomez-Gil-2017-Nitrate assimilation pathway (N,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10605,PHI:7686,UniProt,G3C9N9,GenBank,CCC55815,,,Emoy2,HaRxL23,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens,,YVS,29106332,PubMed,10.1094/MPMI-07-17-0169-FI,Mol Plant Microbe Interact.2017 Nov 6,johnmcd@vt.edu,HaRxL23 and PsAvh73 suppressed PAMP-triggered immunity (PTI) in N. benthamiana and effector-triggered immunity (ETI) in soybean and transgenic Arabidopsis constitutively expressing HaRxL23 or PsAvh73 exhibited suppression of PTI and enhancement of bacterial and oomycete virulence.,D Deb 2017,2017,2 genes,Deb-2017-Conserved RxLR effectors from oomycet,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10606,PHI:7687,UniProt,E0W5A0,GenBank,AEK80609,,,P7064,PsAvh73,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,downy mildew (Arabidopsis),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: direct injection,proteins were transiently expressed in N. benthamiana leaf cells by agroinfiltration using Agrobacterium tumefaciens,,YVS,29106332,PubMed,10.1094/MPMI-07-17-0169-FI,Mol Plant Microbe Interact.2017 Nov 6,johnmcd@vt.edu,HaRxL23 and PsAvh73 suppressed PAMP-triggered immunity (PTI) in N. benthamiana and effector-triggered immunity (ETI) in soybean and transgenic Arabidopsis constitutively expressing HaRxL23 or PsAvh73 exhibited suppression of PTI and enhancement of bacterial and oomycete virulence.,D Deb 2017,2017,2 genes,Deb-2017-Conserved RxLR effectors from oomycet,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10607,PHI:7686,UniProt,G3C9N9,GenBank,CCC55815,,,Emoy2,HaRxL23,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,soybean leaves were transformed by particle bombardment using a mixture of plasmid DNA comprising the effector DNA,,YVS,29106332,PubMed,10.1094/MPMI-07-17-0169-FI,Mol Plant Microbe Interact.2017 Nov 6,johnmcd@vt.edu,HaRxL23 and PsAvh73 suppressed PAMP-triggered immunity (PTI) in N. benthamiana and effector-triggered immunity (ETI) in soybean and transgenic Arabidopsis constitutively expressing HaRxL23 or PsAvh73 exhibited suppression of PTI and enhancement of bacterial and oomycete virulence.,D Deb 2017,2017,2 genes,Deb-2017-Conserved RxLR effectors from oomycet,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10608,PHI:7687,UniProt,E0W5A0,GenBank,AEK80609,,,P7064,PsAvh73,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,soybean leaves were transformed by particle bombardment using a mixture of plasmid DNA comprising the effector DNA,,YVS,29106332,PubMed,10.1094/MPMI-07-17-0169-FI,Mol Plant Microbe Interact.2017 Nov 6,johnmcd@vt.edu,HaRxL23 and PsAvh73 suppressed PAMP-triggered immunity (PTI) in N. benthamiana and effector-triggered immunity (ETI) in soybean and transgenic Arabidopsis constitutively expressing HaRxL23 or PsAvh73 exhibited suppression of PTI and enhancement of bacterial and oomycete virulence.,D Deb 2017,2017,2 genes,Deb-2017-Conserved RxLR effectors from oomycet,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10609,PHI:7686,UniProt,G3C9N9,GenBank,CCC55815,,,Emoy2,HaRxL23,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: dipping,the constructs were transferred to Agrobacterium tumefaciens GV3101 strain by electroporation and transformed into Arabidopsis Col-0 by the floral dip method,,YVS,29106332,PubMed,10.1094/MPMI-07-17-0169-FI,Mol Plant Microbe Interact.2017 Nov 6,johnmcd@vt.edu,HaRxL23 and PsAvh73 suppressed PAMP-triggered immunity (PTI) in N. benthamiana and effector-triggered immunity (ETI) in soybean and transgenic Arabidopsis constitutively expressing HaRxL23 or PsAvh73 exhibited suppression of PTI and enhancement of bacterial and oomycete virulence.,D Deb 2017,2017,2 genes,Deb-2017-Conserved RxLR effectors from oomycet,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10610,PHI:7687,UniProt,E0W5A0,GenBank,AEK80609,,,P7064,PsAvh73,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: dipping,the constructs were transferred to Agrobacterium tumefaciens GV3101 strain by electroporation and transformed into Arabidopsis Col-0 by the floral dip method,,YVS,29106332,PubMed,10.1094/MPMI-07-17-0169-FI,Mol Plant Microbe Interact.2017 Nov 6,johnmcd@vt.edu,HaRxL23 and PsAvh73 suppressed PAMP-triggered immunity (PTI) in N. benthamiana and effector-triggered immunity (ETI) in soybean and transgenic Arabidopsis constitutively expressing HaRxL23 or PsAvh73 exhibited suppression of PTI and enhancement of bacterial and oomycete virulence.,D Deb 2017,2017,2 genes,Deb-2017-Conserved RxLR effectors from oomycet,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10611,PHI:7688,UniProt,P33383,GenBank,CAD00733,,,EGD-e,orfX,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,nucleomodulin secreted protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29089430,PubMed,10.1128/mBio.01550-17,MBio.2017 Oct 31;8(5). pii: e01550-17,olivier.dussurget@pasteur.fr,OrfX contributes to Listeria multiplication and dampens the oxidative response in macrophages.,A Prokop 2017,2017,1 gene,"Prokop-2017-OrfX, a Nucleomodulin Required for",BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10612,PHI:7689,UniProt,D6XQY8,GenBank,ADI35182,,,v225d,gGT,,hp1118::kan (ΔgGT),,,,,210,Helicobacter pylori,,PMSS1,gastric infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,stomach,γ-glutamyl transferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29057967,PubMed,10.1038/s41598-017-14028-1,Sci Rep.2017 Oct 20;7(1):13636,markus.gerhard@tum.de,"Enzymatic activity of gGT was not only important for initial colonization by the bacterium, but that it profoundly changed the stomach milieu instructing differential recruitment of immune cells into the gastric mucosa.",S Wüstner 2017,2017,1 gene,Wustner-2017-Helicobacter pylori gamma-glutamy,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10613,PHI:7690,UniProt,Q6D5N3,GenBank,CAG74909,,,SCRI1043,ECA2008,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,soft rot (potato); blackleg disease (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Maris Piper,,,tuber,cyclic-di-GMP signalling protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,24760967,PubMed,10.1099/mic.0.076828-0,Microbiology.2014 Jul;160(Pt 7):1427-39,gpcs2@cam.ac.uk,The tuber rot levels were increased three fold for strains overexpressing ECA2008 and decreased when overexpressing ECA3851.,H Tan 2014,2014,2 genes,Tan-2014-Comprehensive overexpression analysis,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10614,PHI:7691,UniProt,Q6D0E8,GenBank,CAG76749,,,SCRI1043,ECA3851,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,soft rot (potato); blackleg disease (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Maris Piper,,,tuber,cyclic-di-GMP signalling protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,24760967,PubMed,10.1099/mic.0.076828-0,Microbiology.2014 Jul;160(Pt 7):1427-39,gpcs2@cam.ac.uk,The tuber rot levels were increased three fold for strains overexpressing ECA2008 and decreased when overexpressing ECA3851.,H Tan 2014,2014,2 genes,Tan-2014-Comprehensive overexpression analysis,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10615,PHI:7692,UniProt,Q4WQM5,GenBank,EAL89459,,,Af293,FlcA,chromosome 4,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,putative flavin transporter,,,,loss of pathogenicity,,,,,,,,reduced,,no,"bathophenanthroline disulfonic acid (BPS); 3-(2-pyridyl)-5,6-bis(4-phenylsulfonic acid)-1,2,4-triazine (ferrozine); FeSO4; LiCl; MnCl2; CaCl2; EDTA; cyclosporin; calcofluor white (CFW); congo red (CR); sodium dodecyl sulfate (SDS); t-butyl hydroxyperoxide; paraquat","bathophenanthroline disulfonic acid (BPS): CHEBI:78159; 3-(2-pyridyl)-5,6-bis(4-phenylsulfonic acid)-1,2,4-triazine (ferrozine): CAS:32796-55-7; FeSO4: CHEBI:75832; LiCl: CHEBI:48607; MnCl2: CHEBI:63041; CaCl2: CHEBI:3312; ethylene glycol tetraacetic acid (EGTA): CAS:67-42-5; cyclosporine: CHEBI:4031; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; t-butyl hydroxyperoxide: CHEBI:64090; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27652896,PubMed,10.1080/21505594.2016.1239010,Virulence.2017 Aug 18;8(6):797-809,ggoldman@usp.br,ΔflcA-C mutants showed reduced flavin adenine dinucleotide (FAD) and were avirulent in a low dose murine infection model.,P A de Castro 2016,2016,3 genes,de Castro-2016-The putative flavin carrier fam,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10616,PHI:7693,UniProt,Q4WZA3,GenBank,EAL94062,,,Af293,FlcB,chromosome 2,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,putative flavin transporter,,,,loss of pathogenicity,,,,,,,,,,no,"bathophenanthroline disulfonic acid (BPS); 3-(2-pyridyl)-5,6-bis(4-phenylsulfonic acid)-1,2,4-triazine (ferrozine); FeSO4; LiCl; MnCl2; CaCl2; EDTA; cyclosporin; calcofluor white (CFW); congo red (CR); sodium dodecyl sulfate (SDS); t-butyl hydroxyperoxide; paraquat","bathophenanthroline disulfonic acid (BPS): CHEBI:78159; 3-(2-pyridyl)-5,6-bis(4-phenylsulfonic acid)-1,2,4-triazine (ferrozine): CAS:32796-55-7; FeSO4: CHEBI:75832; LiCl: CHEBI:48607; MnCl2: CHEBI:63041; CaCl2: CHEBI:3312; ethylene glycol tetraacetic acid (EGTA): CAS:67-42-5; cyclosporin: CHEBI:4031; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; t-butyl hydroxyperoxide: CHEBI:64090; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27652896,PubMed,10.1080/21505594.2016.1239010,Virulence.2017 Aug 18;8(6):797-809,ggoldman@usp.br,ΔflcA-C mutants showed reduced flavin adenine dinucleotide (FAD) and were avirulent in a low dose murine infection model.,P A de Castro 2016,2016,3 genes,de Castro-2016-The putative flavin carrier fam,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10617,PHI:7694,UniProt,Q4WHA4,GenBank,EAL87701,,,Af293,FlcC,chromosome 2,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,putative flavin transporter,,,,loss of pathogenicity,,,,,,,,,,no,"bathophenanthroline disulfonic acid (BPS); 3-(2-pyridyl)-5,6-bis(4-phenylsulfonic acid)-1,2,4-triazine (ferrozine); FeSO4; LiCl; MnCl2; CaCl2; EDTA; cyclosporin; calcofluor white (CFW); congo red (CR); sodium dodecyl sulfate (SDS); t-butyl hydroxyperoxide; paraquat","bathophenanthroline disulfonic acid (BPS): CHEBI:78159; 3-(2-pyridyl)-5,6-bis(4-phenylsulfonic acid)-1,2,4-triazine (ferrozine): CAS:32796-55-7; FeSO4: CHEBI:75832; LiCl: CHEBI:48607; MnCl2: CHEBI:63041; CaCl2: CHEBI:3312; ethylene glycol tetraacetic acid (EGTA): CAS:67-42-5; cyclosporin: CHEBI:4031; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; t-butyl hydroxyperoxide: CHEBI:64090; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,27652896,PubMed,10.1080/21505594.2016.1239010,Virulence.2017 Aug 18;8(6):797-809,ggoldman@usp.br,ΔflcA-C mutants showed reduced flavin adenine dinucleotide (FAD) and were avirulent in a low dose murine infection model.,P A de Castro 2016,2016,3 genes,de Castro-2016-The putative flavin carrier fam,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10618,PHI:7695,UniProt,A7F6T4,GenBank,EDN98455,,,1980,SCD1,,,,,,,5180,Sclerotinia sclerotiorum,,,white mold,eudicots,3708,Brassica napus (related: rape),cv. Westar,,,leaf,scytalone dehydratase,,,,unaffected pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29024255,PubMed,10.1111/mpp.12627,Mol Plant Pathol.2017 Oct 11,liangyuet@126.com,"Disruption ofSCD1orTHR1did not change thepathogenicityof the fungus, but resulted in slower radialgrowth, less biomass, wider-angled hyphae branches, impairedsclerotialdevelopmentand decreased resistance to ultraviolet light.",Y Liang 2017,2017,2 genes,Liang-2017-Deficiency of the melanin biosynthe,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10619,PHI:7696,UniProt,A7F6T5,GenBank,EDN98456,,,1980,THR1,,,,,,,5180,Sclerotinia sclerotiorum,,,white mold,eudicots,3708,Brassica napus (related: rape),cv. Westar,,,leaf,trihydroxynaphthalene reductase,,,,unaffected pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29024255,PubMed,10.1111/mpp.12627,Mol Plant Pathol.2017 Oct 11,liangyuet@126.com,"Disruption ofSCD1orTHR1did not change thepathogenicityof the fungus, but resulted in slower radialgrowth, less biomass, wider-angled hyphae branches, impairedsclerotialdevelopmentand decreased resistance to ultraviolet light.",Y Liang 2017,2017,2 genes,Liang-2017-Deficiency of the melanin biosynthe,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10620,PHI:7697,UniProt,A0A0F7A0T2,GenBank,AKF50594,,,HS191,BphP1,,,,Bsi; Smp,UniProt: Q4ZSY4; GenBank: AAY37738; UniProt: Q4ZTI4; GenBank: AAY37538,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Bush Blue Lake 274,,,leaf,red/far-red-light-sensing bacteriophytochrome,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29066541,PubMed,10.1128/mBio.01178-17,MBio.2017 Oct 24;8(5). pii: e01178-17,gbeattie@iastate.edu,"BphP1, but neither Bsi nor Smp, contributed to leaf colonization; loss of bphP1 reduced survival on leaves immediately following inoculation but enhanced the size of the subsequently established populations.",R McGrane 2017,2017,4 genes,McGrane-2017-Pseudomonas syringae pv. syringae,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10621,PHI:7698,UniProt,Q4ZSY4,GenBank,AAY37738,,,B728a,Bsi,,,,Bsi; Smp,UniProt: Q4ZSY4; GenBank: AAY37738; UniProt: Q4ZTI4; GenBank: AAY37538,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Bush Blue Lake 274,,,leaf,bacteriophytochrome-regulated swarming inhibitor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29066541,PubMed,10.1128/mBio.01178-17,MBio.2017 Oct 24;8(5). pii: e01178-17,gbeattie@iastate.edu,"BphP1, but neither Bsi nor Smp, contributed to leaf colonization; loss of bphP1 reduced survival on leaves immediately following inoculation but enhanced the size of the subsequently established populations.",R McGrane 2017,2017,4 genes,McGrane-2017-Pseudomonas syringae pv. syringae,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10622,PHI:7699,UniProt,Q4ZTI4,GenBank,AAY37538,,,B728a,Smp,,,,Bsi; Smp,UniProt: Q4ZSY4; GenBank: AAY37738; UniProt: Q4ZTI4; GenBank: AAY37538,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Bush Blue Lake 274,,,leaf,swarm motility-promoting regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29066541,PubMed,10.1128/mBio.01178-17,MBio.2017 Oct 24;8(5). pii: e01178-17,gbeattie@iastate.edu,"BphP1, but neither Bsi nor Smp, contributed to leaf colonization; loss of bphP1 reduced survival on leaves immediately following inoculation but enhanced the size of the subsequently established populations.",R McGrane 2017,2017,4 genes,McGrane-2017-Pseudomonas syringae pv. syringae,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10623,PHI:7700,UniProt,Q4ZSY3,GenBank,AAY37739,,,B728a,Lov,,,,Bsi; Smp,UniProt: Q4ZSY4; GenBank: AAY37738; UniProt: Q4ZTI4; GenBank: AAY37538,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Bush Blue Lake 274,,,leaf,light-oxygen-voltage (LOV) domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29066541,PubMed,10.1128/mBio.01178-17,MBio.2017 Oct 24;8(5). pii: e01178-17,gbeattie@iastate.edu,"BphP1, but neither Bsi nor Smp, contributed to leaf colonization; loss of bphP1 reduced survival on leaves immediately following inoculation but enhanced the size of the subsequently established populations.",R McGrane 2017,2017,4 genes,McGrane-2017-Pseudomonas syringae pv. syringae,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10624,PHI:7701,UniProt,Q6S9D7,GenBank,AAR24348,,,,Pb14-3-3,,,,,,,121759,Paracoccidioides brasiliensis,502780,Pb18,paracoccidioidomycosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,26646480,PubMed,10.1080/21505594.2015.1122166,Virulence.2016;7(2):72-84,ana.marisa@uol.com.br,Pb14-3-3 silencing affected yeast cell morphology and morphological transition without affecting cell viability or fungal growth.,C M Marcos 2015,2015,1 gene,Marcos-2015-Decreased expression of 14-3-3 in,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10625,PHI:7702,UniProt,P60378,GenBank,BAB57159,,,Mu50,spx,,,,,,,1280,Staphylococcus aureus,,NCTC 8325-4,skin infection; food poisoning; respiratory disease,,,,Lethal pathogen phenotype,,,,essential gene which is a thiol/oxidative stress sensor,,,,lethal,,,,,,,,,,yes,,,,,,,gene mutation; gene complementation,,,YVS,27432833,PubMed,10.1128/JB.00261-16,J Bacteriol.2016 Sep 9;198(19):2719-31,William.Kelley@unige.ch,"The generation of rifampin resistance libraries led to the discovery of an additional rpoB mutation, R484H, which supported strains with the spx disruption, and also multicopy expression of either trxA (encoding thioredoxin) or trxB (encoding thioredoxin reductase) supported strains with the deletion of spx.",M Villanueva 2016,2016,1 gene,Villanueva-2016-Rifampicin resistant rpoB alle,BATCH_075A,2017-11-01,MC,,,,,,,,,,,,,
,,Record 10626,PHI:7703,UniProt,A0A290WGZ0,GenBank,ATD50206,,,Vd991,VEDA_05193,,,,,,PHI:7704; PHI:7705; PHI:7706; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,"cupin, RmIC-type",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10627,PHI:7704,UniProt,A0A290WHN4,GenBank,ATD50207,,,Vd991,VEDA_05194,,,,,,PHI:7703; PHI:7705; PHI:7706; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,NAD(P)-binding domain protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10628,PHI:7705,UniProt,A0A290WHP2,GenBank,ATD50211,,,Vd991,VEDA_05195,,,,,,PHI:7703; PHI:7704; PHI:7706; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,glucose-methanol-choline oxidoreductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10629,PHI:7706,UniProt,A0A290WI18,GenBank,ATD50212,,,Vd991,VEDA_05196,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,major facilitator superfamily,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10630,PHI:7707,UniProt,A0A290WH42,GenBank,ATD50208,,,Vd991,VEDA_05197,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7706; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,NAD(P)-binding domain protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10631,PHI:7708,UniProt,A0A290WFC9,GenBank,ATD50209,,,Vd991,VEDA_05198,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7706; PHI:7707; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,NAD(P)-binding domain protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10632,PHI:7709,UniProt,A0A290WFK0,GenBank,ATD50210,,,Vd991,VEDA_05199,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7706; PHI:7707; PHI:7708,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,involved in NAPE metabolic process,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10633,PHI:7703,UniProt,A0A290WGZ0,GenBank,ATD50206,,,Vd991,VEDA_05193,,,,,,PHI:7704; PHI:7705; PHI:7706; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,"cupin, RmIC-type",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10634,PHI:7704,UniProt,A0A290WHN4,GenBank,ATD50207,,,Vd991,VEDA_05194,,,,,,PHI:7703; PHI:7705; PHI:7706; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10635,PHI:7705,UniProt,A0A290WHP2,GenBank,ATD50211,,,Vd991,VEDA_05195,,,,,,PHI:7703; PHI:7704; PHI:7706; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,glucose-methanol-choline oxidoreductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10636,PHI:7706,UniProt,A0A290WI18,GenBank,ATD50212,,,Vd991,VEDA_05196,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,major facilitator superfamily,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10637,PHI:7707,UniProt,A0A290WH42,GenBank,ATD50208,,,Vd991,VEDA_05197,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7706; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10638,PHI:7708,UniProt,A0A290WFC9,GenBank,ATD50209,,,Vd991,VEDA_05198,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7706; PHI:7707; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10639,PHI:7709,UniProt,A0A290WFK0,GenBank,ATD50210,,,Vd991,VEDA_05199,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7706; PHI:7707; PHI:7708,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,involved in NAPE metabolic process,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10640,PHI:7703,UniProt,A0A290WGZ0,GenBank,ATD50206,,,Vd991,VEDA_05193,,,,,,PHI:7704; PHI:7705; PHI:7706; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,"cupin, RmIC-type",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10641,PHI:7704,UniProt,A0A290WHN4,GenBank,ATD50207,,,Vd991,VEDA_05194,,,,,,PHI:7703; PHI:7705; PHI:7706; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10642,PHI:7705,UniProt,A0A290WHP2,GenBank,ATD50211,,,Vd991,VEDA_05195,,,,,,PHI:7703; PHI:7704; PHI:7706; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,glucose-methanol-choline oxidoreductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10643,PHI:7706,UniProt,A0A290WI18,GenBank,ATD50212,,,Vd991,VEDA_05196,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7707; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,major facilitator superfamily,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10644,PHI:7707,UniProt,A0A290WH42,GenBank,ATD50208,,,Vd991,VEDA_05197,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7706; PHI:7708; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10645,PHI:7708,UniProt,A0A290WFC9,GenBank,ATD50209,,,Vd991,VEDA_05198,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7706; PHI:7707; PHI:7709,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10646,PHI:7709,UniProt,A0A290WFK0,GenBank,ATD50210,,,Vd991,VEDA_05199,,,,,,PHI:7703; PHI:7704; PHI:7705; PHI:7706; PHI:7707; PHI:7708,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,involved in NAPE metabolic process,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10647,PHI:7706,UniProt,A0A290WI18,GenBank,ATD50212,,,Vd991,VEDA_05196,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,major facilitator superfamily,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10648,PHI:7707,UniProt,A0A290WH42,GenBank,ATD50208,,,Vd991,VEDA_05197,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,NAD(P)-binding domain protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10649,PHI:7708,UniProt,A0A290WFC9,GenBank,ATD50209,,,Vd991,VEDA_05198,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,NAD(P)-binding domain protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10650,PHI:7706,UniProt,A0A290WI18,GenBank,ATD50212,,,Vd991,VEDA_05196,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,major facilitator superfamily,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10651,PHI:7707,UniProt,A0A290WH42,GenBank,ATD50208,,,Vd991,VEDA_05197,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10652,PHI:7708,UniProt,A0A290WFC9,GenBank,ATD50209,,,Vd991,VEDA_05198,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10653,PHI:7706,UniProt,A0A290WI18,GenBank,ATD50212,,,Vd991,VEDA_05196,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,major facilitator superfamily,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10654,PHI:7707,UniProt,A0A290WH42,GenBank,ATD50208,,,Vd991,VEDA_05197,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10655,PHI:7708,UniProt,A0A290WFC9,GenBank,ATD50209,,,Vd991,VEDA_05198,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10656,PHI:7706,UniProt,A0A290WI18,GenBank,ATD50212,,,Vd991,VEDA_05196,,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,major facilitator superfamily,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10657,PHI:7707,UniProt,A0A290WH42,GenBank,ATD50208,,,Vd991,VEDA_05197,,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,NAD(P)-binding domain protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10658,PHI:7708,UniProt,A0A290WFC9,GenBank,ATD50209,,,Vd991,VEDA_05198,,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,NAD(P)-binding domain protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10659,PHI:7706,UniProt,A0A290WI18,GenBank,ATD50212,,,Vd991,VEDA_05196,,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,major facilitator superfamily,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10660,PHI:7707,UniProt,A0A290WH42,GenBank,ATD50208,,,Vd991,VEDA_05197,,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10661,PHI:7708,UniProt,A0A290WFC9,GenBank,ATD50209,,,Vd991,VEDA_05198,,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10662,PHI:7706,UniProt,A0A290WI18,GenBank,ATD50212,,,Vd991,VEDA_05196,,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,major facilitator superfamily,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10663,PHI:7707,UniProt,A0A290WH42,GenBank,ATD50208,,,Vd991,VEDA_05197,,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10664,PHI:7708,UniProt,A0A290WFC9,GenBank,ATD50209,,,Vd991,VEDA_05198,,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Capitata,,,leaf,NAD(P)-binding domain protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenes,,,YVS,29084346,PubMed,10.1111/nph.14861,New Phytol.2018 Jan;217(2):756-770,kvsubbarao@ucdavis.edu,Phylogenetic analyses suggested that G-LSR2 genes was acquired from Fusarium oxysporum f. sp. vasinfectum through horizontal gene transfer.,J Y Chen 2017,2017,7 genes,Chen-2017-Comparative genomics reveals cotton-,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10665,PHI:7710,UniProt,A0A0T9ML40,GenBank,CNG22488,,,R819,YopM,,,,,,,633,Yersinia pseudotuberculosis,,32777,zoonotic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,27569559,PubMed,10.1016/j.chom.2016.07.018,CellHostMicrobe.2016 Sep 14;20(3):296-306,james.bliska@stonybrook.edu,"Host gene alteration data available for pyrin (Mefv gene) . The attenuation of a yopM mutant was fully reversed in pyrin knock-out mice, demonstrating that YopM inhibited pyrin to promote virulence.",L K Chung 2016,2016,1 gene,Chung-2016-The Yersinia Virulence Factor YopM,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10666,PHI:7711,UniProt,P55980,GenBank,AAD07614,,,26695,CagA,,,,,,,210,Helicobacter pylori,,,gastric infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,enterocyte,virulence factor and cytotoxin associated protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: transgenic,,,YVS,29049360,PubMed,10.1371/journal.ppat.1006631,PLoS Pathog.2017 Oct 19;13(10):e1006631,kguillem@uoregon.edu,"The data showed that expression of CagA within stem cells, but not enterocytes, of the gut epithelium was sufficient to promote excess cell proliferation in the Drosophila midgut.",T A Jones 2017,2017,1 gene,Jones-2017-The bacterial virulence factor CagA,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10667,PHI:7711,UniProt,P55980,GenBank,AAD07614,,,26695,CagA,,,,,,,210,Helicobacter pylori,,,gastric infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,intestinal stem cell,virulence factor and cytotoxin associated protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenic,,,YVS,29049360,PubMed,10.1371/journal.ppat.1006631,PLoS Pathog.2017 Oct 19;13(10):e1006631,kguillem@uoregon.edu,"The data showed that expression of CagA within stem cells, but not enterocytes, of the gut epithelium was sufficient to promote excess cell proliferation in the Drosophila midgut.",T A Jones 2017,2017,1 gene,Jones-2017-The bacterial virulence factor CagA,BATCH_075B,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10668,PHI:7712,UniProt,A0A2P1E328,GenBank,KY861062,,,,CgRGS1,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,regulator of G-protein signaling,,,G-protein signaling,reduced virulence,,yes,,,,,reduced,reduced,aberrant,no,H2O2; sodium dodecyl sulfate (SDS); NaCl; sorbitol; sucrose,H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; sucrose: CHEBI:17992,,,,,gene deletion: full; gene complementation,,,YVS,29177869,PubMed,10.1007/s00203-017-1455-1,Arch Microbiol.2017 Nov 25,hdlixiaoyu@126.com,"CgRGS1 deletion mutant had slow vegetative growth, reduced conidia with multi-end germination, low appressorium formation rate, high resistance to oxidative stress and SDS.",Z Q Liu 2017,2017,1 gene,Liu-2017-Functional analysis of a regulator of,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10669,PHI:7713,UniProt,Q7NBK7,GenBank,AAP56611,,,R,MGA_1102,,,,,,,2096,Mycoplasmoides gallisepticum,,Ap3AS,airsacculitis,birds,9031,Gallus gallus (related: chicken),,,,,"hypothetical membrane protein, zinc peptidase-like motif",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28348054,PubMed,10.1128/IAI.00023-17,Infect Immun.2017 May 23;85(6). pii: e00023-17,glenfb@unimelb.edu.au,"The three hypothetical gene mutants and the two with insertions in oppD1 were used to infect chickens, and all five were shown to have a reduced capacity to induce respiratory tract lesions.",C W Tseng 2017,2017,4 genes,Tseng-2017-The oppD gene and putative peptidas,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10670,PHI:7714,UniProt,Q7NAE8,GenBank,AAP57060,,,R,MGA_0588,,,,,,,2096,Mycoplasmoides gallisepticum,,Ap3AS,airsacculitis,birds,9031,Gallus gallus (related: chicken),,,,,"hypothetical membrane protein, multiple paralogs",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28348054,PubMed,10.1128/IAI.00023-17,Infect Immun.2017 May 23;85(6). pii: e00023-17,glenfb@unimelb.edu.au,"The three hypothetical gene mutants and the two with insertions in oppD1 were used to infect chickens, and all five were shown to have a reduced capacity to induce respiratory tract lesions.",C W Tseng 2017,2017,4 genes,Tseng-2017-The oppD gene and putative peptidas,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10671,PHI:7715,UniProt,Q7NAX1,GenBank,AAP56864,,,R,MGA_0220,,,,,,,2096,Mycoplasmoides gallisepticum,,Ap3AS,airsacculitis,birds,9031,Gallus gallus (related: chicken),,,,,oligopeptide transporter ATP-binding protein OppD1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28348054,PubMed,10.1128/IAI.00023-17,Infect Immun.2017 May 23;85(6). pii: e00023-17,glenfb@unimelb.edu.au,"The three hypothetical gene mutants and the two with insertions in oppD1 were used to infect chickens, and all five were shown to have a reduced capacity to induce respiratory tract lesions.",C W Tseng 2017,2017,4 genes,Tseng-2017-The oppD gene and putative peptidas,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10672,PHI:7716,UniProt,Q7NBL9,GenBank,AAP56599,,,R,MGA_1079,,,,,,,2096,Mycoplasmoides gallisepticum,,Ap3AS,airsacculitis,birds,9031,Gallus gallus (related: chicken),,,,,"hypothetical lipoprotein, trypsin-like peptidase motif",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28348054,PubMed,10.1128/IAI.00023-17,Infect Immun.2017 May 23;85(6). pii: e00023-17,glenfb@unimelb.edu.au,"The three hypothetical gene mutants and the two with insertions in oppD1 were used to infect chickens, and all five were shown to have a reduced capacity to induce respiratory tract lesions.",C W Tseng 2017,2017,4 genes,Tseng-2017-The oppD gene and putative peptidas,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10673,PHI:7717,UniProt,I1S0H5,GenBank,XP_011319150,,,PH-1; NRRL 31084,FgOXP1,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,5-oxoprolinase,,,,reduced virulence,no,,,,,wild type,wild type,,,no,NaCl; KCl; H2O2; Congo red; SDS; calcofluor white; sorbitol,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,28918485,PubMed,10.1007/s00294-017-0747-y,Curr Genet.2017 Sep 16,wenhuiz@fafu.edu.cn,"Double deletion of FgOXP1 and FgOXP2 led to more severe defects in conidiation, DON production and virulence on plants, suggesting that both FgOXP1 and FgOXP2 play a role in fungal development and plant colonization.",P Yang 2017,2017,2 genes,Yang-2017-The 5-oxoprolinase is required for c,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10674,PHI:7718,UniProt,I1RLT3,GenBank,XP_011323371,,,PH-1; NRRL 31084,FgOXP2,chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,5-oxoprolinase,,,,reduced virulence,yes,,,,,reduced,reduced,,,no,NaCl; KCl; H2O2; Congo red; SDS; calcofluor white; sorbitol,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,28918485,PubMed,10.1007/s00294-017-0747-y,Curr Genet.2017 Sep 16,wenhuiz@fafu.edu.cn,"Double deletion of FgOXP1 and FgOXP2 led to more severe defects in conidiation, DON production and virulence on plants, suggesting that both FgOXP1 and FgOXP2 play a role in fungal development and plant colonization.",P Yang 2017,2017,2 genes,Yang-2017-The 5-oxoprolinase is required for c,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10675,PHI:7717,UniProt,I1S0H5,GenBank,XP_011319150,,,PH-1; NRRL 31084,FgOXP1,chromosome 1,,,,,PHI:7718,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,5-oxoprolinase,,,,reduced virulence,yes,,,,,reduced,reduced,,,no,NaCl; KCl; H2O2; Congo red; SDS; calcofluor white; sorbitol,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,28918485,PubMed,10.1007/s00294-017-0747-y,Curr Genet.2017 Sep 16,wenhuiz@fafu.edu.cn,"Double deletion of FgOXP1 and FgOXP2 led to more severe defects in conidiation, DON production and virulence on plants, suggesting that both FgOXP1 and FgOXP2 play a role in fungal development and plant colonization.",P Yang 2017,2017,2 genes,Yang-2017-The 5-oxoprolinase is required for c,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10676,PHI:7718,UniProt,I1RLT3,GenBank,XP_011323371,,,PH-1; NRRL 31084,FgOXP2,chromosome 3,,,,,PHI:7717,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,5-oxoprolinase,,,,reduced virulence,yes,,,,,reduced,reduced,,,no,NaCl; KCl; H2O2; Congo red; SDS; calcofluor white; sorbitol,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,28918485,PubMed,10.1007/s00294-017-0747-y,Curr Genet.2017 Sep 16,wenhuiz@fafu.edu.cn,"Double deletion of FgOXP1 and FgOXP2 led to more severe defects in conidiation, DON production and virulence on plants, suggesting that both FgOXP1 and FgOXP2 play a role in fungal development and plant colonization.",P Yang 2017,2017,2 genes,Yang-2017-The 5-oxoprolinase is required for c,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10677,PHI:7719,UniProt,A0A1D8PS71,GenBank,AOW30987,,,SC5314,orf19.3727,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,epithelial cell,phytase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29216308,PubMed,10.1371/journal.pone.0189219,PLoS One.2017 Dec 7;12(12):e0189219,paulwktsang@vtc.edu.hk,"Disruption of C. albicans orf19.3727 led to decreased phytase activity, reduced ability to form hyphae, attenuated in vitro adhesion and reduced ability to penetrate human epithelium, which are the major virulence attributes of this yeast.",P W Tsang 2017,2017,1 gene,Tsang-2017-Candida albicans orf19.3727 encodes,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10678,PHI:7720,UniProt,Q8XK42,GenBank,BAB81267,,,13,AgrB,,,,,,,1502,Clostridium perfringens,,CP1,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 708,,,intestine,quorum sensing system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,28373356,PubMed,10.1128/IAI.00975-16,Infect Immun.2017 May 23;85(6). pii: e00975-16,Joshua.Gong@agr.gc.ca,Agr-like QS system was found to be critical for NE pathogenesis and netB was potentially involved in mediating its effects.,Q Yu 2017,2017,1 gene,Yu-2017-The Agr-like quorum sensing system is,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10679,PHI:7721,UniProt,P18013,GenBank,AAA26524,,,,IpaD,,D144A/N146A/Y149A,,IpaB,UniProt: P18011; GenBank: AAA26522,,623,Shigella flexneri,,serotype 2a strain 2457T,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,type three secretion system tip protein,,,,reduced virulence,,,,,,,,,,no,Congo red,Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,YVS,29134812,PubMed,10.1021/acs.biochem.7b00836,Biochemistry.2017 Dec 12;56(49):6503-6514,nick.dickenson@usu.edu,"Engineered mutations within the pi-helix altered the pathogen's response to DOC, with one mutant construct (IpaD-D144A/N146A/Y149A) in particular exhibiting an unprecedented reduction in virulence following DOC exposure. The identified pi-Helix in IpaD regulates IpaD-IpaB interaction and is critical for DOC enhancement of cellular invasion.",A R Bernard 2017,2017,1 gene,Bernard-2017-Deoxycholate-Enhanced Shigella Vi,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10680,PHI:7722,UniProt,G2YTS7,GenBank,CCD54837,,,T4,BcDGAT2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3827,Cicer arietinum (related: Chickpea),cv. P-256,,,leaf,diacylglycerol O-acyl transferase,,,triacylglycerol synthesis,reduced virulence,,,yes,,,,reduced,aberrant,reduced,no,H2O2; NaCl; sorbitol; polyethylene glycol (PEG-8000); Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; polyethylene glycol (PEG-8000): CHEBI:46793; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28940057,PubMed,10.1007/s00294-017-0752-1,Curr Genet.2017 Sep 22,kapoor_rupam@yahoo.com,The insertional mutant was defective in spore production and lacked sclerotia formation as a consequence of lower accumulation of TAG.,ESharma 2017,2017,1 gene,Sharma-2017-Functional analysis of diacylglyce,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10681,PHI:7722,UniProt,G2YTS7,GenBank,CCD54837,,,T4,BcDGAT2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,diacylglycerol O-acyl transferase,,,triacylglycerol synthesis,reduced virulence,,,yes,,,,reduced,aberrant,reduced,no,H2O2; NaCl; sorbitol; polyethylene glycol (PEG-8000); Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; polyethylene glycol (PEG-8000): CHEBI:46793; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28940057,PubMed,10.1007/s00294-017-0752-1,Curr Genet.2017 Sep 22,kapoor_rupam@yahoo.com,The insertional mutant was defective in spore production and lacked sclerotia formation as a consequence of lower accumulation of TAG.,ESharma 2017,2017,1 gene,Sharma-2017-Functional analysis of diacylglyce,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10682,PHI:7722,UniProt,G2YTS7,GenBank,CCD54837,,,T4,BcDGAT2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,diacylglycerol O-acyl transferase,,,triacylglycerol synthesis,reduced virulence,,,yes,,,,reduced,aberrant,reduced,no,H2O2; NaCl; sorbitol; polyethylene glycol (PEG-8000); Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; polyethylene glycol (PEG-8000): CHEBI:46793; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28940057,PubMed,10.1007/s00294-017-0752-1,Curr Genet.2017 Sep 22,kapoor_rupam@yahoo.com,The insertional mutant was defective in spore production and lacked sclerotia formation as a consequence of lower accumulation of TAG.,ESharma 2017,2017,1 gene,Sharma-2017-Functional analysis of diacylglyce,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10683,PHI:7722,UniProt,G2YTS7,GenBank,CCD54837,,,T4,BcDGAT2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf; fruit,diacylglycerol O-acyl transferase,,,triacylglycerol synthesis,reduced virulence,,,yes,,,,reduced,aberrant,reduced,no,H2O2; NaCl; sorbitol; polyethylene glycol (PEG-8000); Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; polyethylene glycol (PEG-8000): CHEBI:46793; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28940057,PubMed,10.1007/s00294-017-0752-1,Curr Genet.2017 Sep 22,kapoor_rupam@yahoo.com,The insertional mutant was defective in spore production and lacked sclerotia formation as a consequence of lower accumulation of TAG.,ESharma 2017,2017,1 gene,Sharma-2017-Functional analysis of diacylglyce,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10684,PHI:7722,UniProt,G2YTS7,GenBank,CCD54837,,,T4,BcDGAT2,,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,13708,Tagetes erecta (related: african marigold),,,,flower,diacylglycerol O-acyl transferase,,,triacylglycerol synthesis,reduced virulence,,,yes,,,,reduced,aberrant,reduced,no,H2O2; NaCl; sorbitol; polyethylene glycol (PEG-8000); Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; polyethylene glycol (PEG-8000): CHEBI:46793; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28940057,PubMed,10.1007/s00294-017-0752-1,Curr Genet.2017 Sep 22,kapoor_rupam@yahoo.com,The insertional mutant was defective in spore production and lacked sclerotia formation as a consequence of lower accumulation of TAG.,ESharma 2017,2017,1 gene,Sharma-2017-Functional analysis of diacylglyce,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10685,PHI:7723,UniProt,Q8XWV5,GenBank,CAD16072,,,GMI1000,speC (RSc2365),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker; cv. Bonny Best,,,xylem; leaf; root,ornithine decarboxylase,,,putrescine biosynthesis,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29215193,PubMed,10.1111/1462-2920.14020,Environ Microbiol.2017 Dec 7,callen@wisc.edu,"A ΔspeC mutant required 15 µM exogenous putrescine to grow and could not grow alone in xylem even when plants were treated with putrescine, however, co-inoculation with wildtype rescued ΔspeC growth, indicating R. solanacearum produced and exported putrescine to xylem sap.",T M Lowe-Power 2017,2017,1 gene,Lowe-Power-2017-Metabolomics of tomato xylem s,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10686,PHI:7724,UniProt,G5EHP7,GenBank,EHA46164,,,70-15,cpk2,chromosome 7,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,root,second catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,unaffected pathogenicity,,no,no,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10687,PHI:7725,UniProt,G4N7T3,GenBank,EHA50887,,,70-15,cpkA,chromosome 4,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,root,catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,unaffected pathogenicity,,yes,yes,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10688,PHI:7724,UniProt,G5EHP7,GenBank,EHA46164,,,70-15,cpk2,chromosome 7,,,,,PHI:7725,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,root,second catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,reduced virulence,,yes,yes,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10689,PHI:7725,UniProt,G4N7T3,GenBank,EHA50887,,,70-15,cpkA,chromosome 4,,,,,PHI:7724,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,root,catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,reduced virulence,,yes,yes,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10690,PHI:7724,UniProt,G5EHP7,GenBank,EHA46164,,,70-15,cpk2,chromosome 7,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,second catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,unaffected pathogenicity,,no,no,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10691,PHI:7725,UniProt,G4N7T3,GenBank,EHA50887,,,70-15,cpkA,chromosome 4,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,reduced virulence,,yes,yes,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10692,PHI:7724,UniProt,G5EHP7,GenBank,EHA46164,,,70-15,cpk2,chromosome 7,,,,,PHI:7725,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,second catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,reduced virulence,,yes,yes,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10693,PHI:7725,UniProt,G4N7T3,GenBank,EHA50887,,,70-15,cpkA,chromosome 4,,,,,PHI:7724,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,reduced virulence,,yes,yes,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10694,PHI:7724,UniProt,G5EHP7,GenBank,EHA46164,,,70-15,cpk2,chromosome 7,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Express,,,leaf,second catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,unaffected pathogenicity,,no,no,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10695,PHI:7725,UniProt,G4N7T3,GenBank,EHA50887,,,70-15,cpkA,chromosome 4,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Express,,,leaf,catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,reduced virulence,,yes,yes,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10696,PHI:7724,UniProt,G5EHP7,GenBank,EHA46164,,,70-15,cpk2,chromosome 7,,,,,PHI:7725,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Express,,,leaf,second catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,reduced virulence,,yes,yes,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10697,PHI:7725,UniProt,G4N7T3,GenBank,EHA50887,,,70-15,cpkA,chromosome 4,,,,,PHI:7724,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Express,,,leaf,catalytic subunit of cyclic AMP-protein kinase A,,,cyclic AMP PKA signaling,reduced virulence,,yes,yes,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,29209297,PubMed,10.3389/fmicb.2017.02289,Front Microbiol.2017 Nov 21;8:2289,naweed@tll.org.sg,"CpkA being the primary PKA, Cpk2 maintains important function(s) in regulating vegetative growth, conidiation and appressorium formation and also contributes to the spatial and temporal regulation of cAMP-PKA signaling in M.oryzae.",P Selvaraj 2017,2017,2 genes,"Selvaraj-2017-Cpk2, a Catalytic Subunit of Cyc",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10698,PHI:7726,UniProt,B8N780,GenBank,EED54761,,,NRRL3357,AfRafA,,,,,,,5059,Aspergillus flavus,,PTS (Δku70 ΔpyrG::AfpyrG),ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,APSES transcription factor,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29209291,PubMed,10.3389/fmicb.2017.02277,Front Microbiol. 2017 Nov 20;8:2277,wshyyl@sina.com,AfRafA and AfStuA exert an antagonistic role in the regulation of biosynthesis of cyclopiazonic acid.,G Yao 2017,2017,2 genes,Yao-2017-Essential APSES Transcription Factors,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10699,PHI:7727,UniProt,B8NBX4,GenBank,EED52997,,,NRRL3357,AfStuA,,,,,,,5059,Aspergillus flavus,,PTS (Δku70 ΔpyrG::AfpyrG),ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,APSES transcription factor,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29209291,PubMed,10.3389/fmicb.2017.02277,Front Microbiol. 2017 Nov 20;8:2277,wshyyl@sina.com,AfRafA and AfStuA exert an antagonistic role in the regulation of biosynthesis of cyclopiazonic acid.,G Yao 2017,2017,2 genes,Yao-2017-Essential APSES Transcription Factors,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10700,PHI:7726,UniProt,B8N780,GenBank,EED54761,,,NRRL3357,AfRafA,,,,,,,5059,Aspergillus flavus,,PTS (Δku70 ΔpyrG::AfpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,APSES transcription factor,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29209291,PubMed,10.3389/fmicb.2017.02277,Front Microbiol. 2017 Nov 20;8:2277,wshyyl@sina.com,AfRafA and AfStuA exert an antagonistic role in the regulation of biosynthesis of cyclopiazonic acid.,G Yao 2017,2017,2 genes,Yao-2017-Essential APSES Transcription Factors,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10701,PHI:7727,UniProt,B8NBX4,GenBank,EED52997,,,NRRL3357,AfStuA,,,,,,,5059,Aspergillus flavus,,PTS (Δku70 ΔpyrG::AfpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,APSES transcription factor,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29209291,PubMed,10.3389/fmicb.2017.02277,Front Microbiol. 2017 Nov 20;8:2277,wshyyl@sina.com,AfRafA and AfStuA exert an antagonistic role in the regulation of biosynthesis of cyclopiazonic acid.,G Yao 2017,2017,2 genes,Yao-2017-Essential APSES Transcription Factors,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10702,PHI:7728,UniProt,A0A140GPJ0,GenBank,AMN16533,,,,BxATG1,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,3350,Pinus thunbergii (related: Japanese black pine),,,,seedling,serine/threonine-protein kinase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,29211016,PubMed,10.3390/ijms18122639,Int J Mol Sci. 2017 Dec 6;18(12). pii: E2639,denglina121@163.com,"With the increase of temperature, the expression level of autophagy genes BxATG1 and BxATG8 of Pine wood nematode ascended and reached peak, and high temperature stimulated autophagy of PWN.",F Wu 2017,2017,2 genes,Wu-2017-Expression Profiling of Autophagy Gene,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10703,PHI:7729,UniProt,A0A140GPJ1,GenBank,AMN16534,,,,BxATG8,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,3350,Pinus thunbergii (related: Japanese black pine),,,,seedling,autophagy related protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,29211016,PubMed,10.3390/ijms18122639,Int J Mol Sci. 2017 Dec 6;18(12). pii: E2639,denglina121@163.com,"With the increase of temperature, the expression level of autophagy genes BxATG1 and BxATG8 of Pine wood nematode ascended and reached peak, and high temperature stimulated autophagy of PWN.",F Wu 2017,2017,2 genes,Wu-2017-Expression Profiling of Autophagy Gene,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10704,PHI:7730,UniProt,Q5ZU55,GenBank,AAU28022,,,Philadelphia 1,LegC4,,legC4::Tn,,,,,446,Legionella pneumophila,866628,130b,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29133401,PubMed,10.1073/pnas.1708553114,Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10446-E10454,craig.roy@yale.edu,"Host gene alteration data available for NLRC4. Loss-of-function mutations in the gene encoding LegC4 resulted in enhanced L. pneumophila in the lungs of infected mice but not within cultured host cells, which indicates LegC4 augments bacterial clearance by the host immune system.",S R Shames 2017,2017,4 genes,Shames-2017-Multiple Legionella pneumophila ef,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10705,PHI:7731,UniProt,Q5ZZC5,GenBank,AAU26193,,,Philadelphia 1,Lpg0086,,lpg0086::Tn,,,,,446,Legionella pneumophila,866628,130b,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29133401,PubMed,10.1073/pnas.1708553114,Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10446-E10454,craig.roy@yale.edu,"Host gene alteration data available for NLRC4. Loss-of-function mutations in the gene encoding LegC4 resulted in enhanced L. pneumophila in the lungs of infected mice but not within cultured host cells, which indicates LegC4 augments bacterial clearance by the host immune system.",S R Shames 2017,2017,4 genes,Shames-2017-Multiple Legionella pneumophila ef,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10706,PHI:7732,UniProt,Q5ZSL2,GenBank,AAU28565,,,Philadelphia 1,Lpg2505,,lpg2505::Tn,,,,,446,Legionella pneumophila,866628,130b,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29133401,PubMed,10.1073/pnas.1708553114,Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10446-E10454,craig.roy@yale.edu,"Host gene alteration data available for NLRC4. Loss-of-function mutations in the gene encoding LegC4 resulted in enhanced L. pneumophila in the lungs of infected mice but not within cultured host cells, which indicates LegC4 augments bacterial clearance by the host immune system.",S R Shames 2017,2017,4 genes,Shames-2017-Multiple Legionella pneumophila ef,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10707,PHI:7733,UniProt,Q5ZV89,GenBank,AAU27633,,,Philadelphia 1,RavY,,ravY::Tn,,,,,446,Legionella pneumophila,866628,130b,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29133401,PubMed,10.1073/pnas.1708553114,Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10446-E10454,craig.roy@yale.edu,"Host gene alteration data available for NLRC4. Loss-of-function mutations in the gene encoding LegC4 resulted in enhanced L. pneumophila in the lungs of infected mice but not within cultured host cells, which indicates LegC4 augments bacterial clearance by the host immune system.",S R Shames 2017,2017,4 genes,Shames-2017-Multiple Legionella pneumophila ef,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10708,PHI:7734,UniProt,G4MY14,GenBank,EHA53542,,,70-15,CYP1,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cyclophilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29128880,PubMed,10.1007/s00438-017-1395-0,Mol Genet Genomics. 2017 Nov 11,georgios.tzelepis@slu.se,The new strain ΔCyp1+ overexpressing PbCYP3 showed increased virulence on rice compared to the ΔCyp1 strain.,K Singh 2017,2017,2 genes,Singh-2017-The immunophilin repertoire of Plas,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10709,PHI:7735,UniProt,A0A0G4J7R2,GenBank,PBRA_003184,,,,PbCYP3,,ΔCyp1+ overexpressing PbCYP3,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cyclophilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression; altered gene expression / gene regulation: overexpression,,,YVS,29128880,PubMed,10.1007/s00438-017-1395-0,Mol Genet Genomics. 2017 Nov 11,georgios.tzelepis@slu.se,The new strain ΔCyp1+ overexpressing PbCYP3 (from Plasmodiophora brassicae) showed increased virulence on rice compared to the ΔCyp1 strain.,K Singh 2017,2017,2 genes,Singh-2017-The immunophilin repertoire of Plas,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10710,PHI:7736,,no data found,,,,,,XopL,,,,,,,53413,Xanthomonas axonopodis,487838,pv. punicae strain ITCCBD0003,bacterial blight,eudicots,22663,Punica granatum (related: Pomegranate),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29193868,PubMed,10.1111/jipb.12615,J Integr Plant Biol. 2017 Nov 29,mondal_kk@rediffmail.com,XopL supports Xap for its sustained multiplication in pomegranate by suppressing plant cell death (PCD) event.,M Soni 2017,2017,1 gene,Soni-2017-Xanthomonas axonopodis pv. punicae e,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10711,PHI:7737,UniProt,A0A1D9QMN1,GenBank,APA16187,,,1980,SsNsd1,chromosome 16,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,leaf,GATA-type IVb zinc-finger transcription factor,,,,loss of pathogenicity,,yes,yes,,,,reduced,aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29227022,PubMed,10.1111/mpp.12651,Mol Plant Pathol. 2017 Dec 11,rollinsj@ufl.edu,"Loss of SsNsd1 function affected sclerotium structural integrity and disrupted ascogonia formation during conditioning for carpogenic germination, as a consequence, apothecium development was abolished.",J Li 2017,2017,1 gene,Li-2017-The GATA-type IVb zinc-finger transcri,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10712,PHI:7737,UniProt,A0A1D9QMN1,GenBank,APA16187,,,1980,SsNsd1,chromosome 16,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4045,Apium graveolens (no common name found),,,,leaf,GATA-type IVb zinc-finger transcription factor,,,,loss of pathogenicity,,yes,yes,,,,reduced,aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29227022,PubMed,10.1111/mpp.12651,Mol Plant Pathol. 2017 Dec 11,rollinsj@ufl.edu,"Loss of SsNsd1 function affected sclerotium structural integrity and disrupted ascogonia formation during conditioning for carpogenic germination, as a consequence, apothecium development was abolished.",J Li 2017,2017,1 gene,Li-2017-The GATA-type IVb zinc-finger transcri,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10713,PHI:7738,UniProt,Q2G2M2,GenBank,AF145699_2,,,SA113,mprF,,L826F; G299V; L473I; T345A,,,,,1280,Staphylococcus aureus,,NCTC 8325-4,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; liver,phosphatidylglycerol lysyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29170657,PubMed,10.3389/fmicb.2017.02199,Front Microbiol. 2017 Nov 9;8:2199,wanghui@pkuph.edu.cn,"The growth of the three mutant strains was slower than that of the parent strains and in vitro serum tolerance of the mutants was decreased, and the lethality and pathogenicity in mice were weakened.",S Li 2017,2017,3 genes,Li-2017-Fitness Cost of Daptomycin-Resistant S,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10714,PHI:7739,UniProt,Q2G2U4,GenBank,AF136709_2,,,8325-4,walK,,Y225N; F473I,,,,,1280,Staphylococcus aureus,,NCTC 8325-4,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; liver,sensor protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29170657,PubMed,10.3389/fmicb.2017.02199,Front Microbiol. 2017 Nov 9;8:2199,wanghui@pkuph.edu.cn,"The growth of the three mutant strains was slower than that of the parent strains and in vitro serum tolerance of the mutants was decreased, and the lethality and pathogenicity in mice were weakened.",S Li 2017,2017,3 genes,Li-2017-Fitness Cost of Daptomycin-Resistant S,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10715,PHI:7740,UniProt,Q2G0D9,GenBank,ABD29799,,,NCTC 8325,graS,,S52N,,,,,1280,Staphylococcus aureus,,NCTC 8325-4,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; liver,sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29170657,PubMed,10.3389/fmicb.2017.02199,Front Microbiol. 2017 Nov 9;8:2199,wanghui@pkuph.edu.cn,"The growth of the three mutant strains was slower than that of the parent strains and in vitro serum tolerance of the mutants was decreased, and the lethality and pathogenicity in mice were weakened.",S Li 2017,2017,3 genes,Li-2017-Fitness Cost of Daptomycin-Resistant S,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10716,PHI:7741,UniProt,G2X8Y4,GenBank,EGY15452,,,VdLs.17,FreB,chromosome 8,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,root; stem; leaf,transmembrane ferric reductase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29177887,PubMed,10.1007/s00294-017-0780-x,Curr Genet. 2017 Nov 25,chenghongmei@caas.cn,FreB mediates the ferric metabolism and is required for the full virulence in V. dahliae.,LRehman 2017,2017,1 gene,Rehman-2017-FreB is involved in the ferric met,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10717,PHI:7742,UniProt,P0A1P6,GenBank,AAL22846,,,LT2; SGSC 1412; ATCC 700720,glnA,,,,,,,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,salmonellosis,primates,9606,Homo sapiens (related: human),U-937 cell line,,,macrophage,glutamine synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; chemical complementation,,,YVS,29150501,PubMed,10.1128/AEM.01838-17,Appl Environ Microbiol. 2017 Nov 17. pii: AEM.01838-17,fliegera@rki.de,"GlnA mutant displayed attenuated entry into host cells and severely reduced levels of exoproteins, including flagellin and several Salmonella pathogenicity island 1 (SPI-1)-dependent secreted virulence. Supplementation with glutamine or genetic reversion of glnA truncation restored growth, cell entry, gene expression and protein abundance. macrophage-like cells",P Aurass 2017,2017,1 gene,Aurass-2017-glnA truncation in Salmonella ente,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10718,PHI:7743,UniProt,Q53653,GenBank,BAF67028,,,Newman,ClfA,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,tibia,clumping factor A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28320836,PubMed,10.1128/IAI.01005-16,Infect Immun. 2017 May 23;85(6). pii: e01005-16,robert_mooney@urmc.rochester.edu,"The increased infection severity in obese/T2D mice is essentially eliminated when clfA is mutated in S. aureus, however, significant difference in infection severity was observed in lean-fed control mice regardless of S. aureus strain, indicating that the effect was specific to obese/T2D mice.",C W Farnsworth 2017,2017,1 gene,Farnsworth-2017-Adaptive upregulation of Clump,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10719,PHI:7744,UniProt,A0A125YUL2,GenBank,EPT25524,,,ME49,ANK1 (TGME49_216140),,chromosome XI,,,,,5811,Toxoplasma gondii,508771,type II strain ME49,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,brain,ankyrin-like tetratricopeptide repeat-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29180989,PubMed,10.3389/fmicb.2017.02210,Front Microbiol. 2017 Nov 13;8:2210,shenbang@mail.hzau.edu.cn,"Disruption of neither of these two genes affected the growth or replication of tachyzoites in vitro, consistent with their minimal expression at this stage. However, mutants lacking ANK1 or DnaK-TPR displayed modest virulence attenuation during mice infection.",J Yang 2017,2017,2 genes,"Yang-2017-ANK1 and DnaK-TPR, Two Tetratricopep",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10720,PHI:7745,UniProt,S8F6A1,GenBank,EPT30267,,,ME49,Dna-K-TPR (TGME49_202020),,chromosome VIIa,,,,,5811,Toxoplasma gondii,508771,type II strain ME49,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,brain,ankyrin-like tetratricopeptide repeat-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29180989,PubMed,10.3389/fmicb.2017.02210,Front Microbiol. 2017 Nov 13;8:2210,shenbang@mail.hzau.edu.cn,"Disruption of neither of these two genes affected the growth or replication of tachyzoites in vitro, consistent with their minimal expression at this stage. However, mutants lacking ANK1 or DnaK-TPR displayed modest virulence attenuation during mice infection.",J Yang 2017,2017,2 genes,"Yang-2017-ANK1 and DnaK-TPR, Two Tetratricopep",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10721,PHI:7744,UniProt,A0A125YUL2,GenBank,EPT25524,,,ME49,ANK1 (TGME49_216140),,chromosome XI,,,,,5811,Toxoplasma gondii,,TgHB2,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,brain,tetratricopeptide repeat-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29180989,PubMed,10.3389/fmicb.2017.02210,Front Microbiol. 2017 Nov 13;8:2210,shenbang@mail.hzau.edu.cn,"Disruption of neither of these two genes affected the growth or replication of tachyzoites in vitro, consistent with their minimal expression at this stage. However, mutants lacking ANK1 or DnaK-TPR displayed modest virulence attenuation during mice infection.",J Yang 2017,2017,2 genes,"Yang-2017-ANK1 and DnaK-TPR, Two Tetratricopep",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10722,PHI:7745,UniProt,S8F6A1,GenBank,EPT30267,,,ME49,Dna-K-TPR (TGME49_202020),,chromosome VIIa,,,,,5811,Toxoplasma gondii,,TgHB2,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,brain,tetratricopeptide repeat-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29180989,PubMed,10.3389/fmicb.2017.02210,Front Microbiol. 2017 Nov 13;8:2210,shenbang@mail.hzau.edu.cn,"Disruption of neither of these two genes affected the growth or replication of tachyzoites in vitro, consistent with their minimal expression at this stage. However, mutants lacking ANK1 or DnaK-TPR displayed modest virulence attenuation during mice infection.",J Yang 2017,2017,2 genes,"Yang-2017-ANK1 and DnaK-TPR, Two Tetratricopep",BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10723,PHI:7746,UniProt,P9WJS3,GenBank,CCP45919,,,H37Rv,rv3109,,,,,,PHI:7747; PHI:7748; PHI:7749; PHI:7750; PHI:7751; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C3HeB/FeJ,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10724,PHI:7747,UniProt,Q6MX13,GenBank,CCP45920,,,H37Rv,rv3110,,,,,,PHI:7746; PHI:7748; PHI:7749; PHI:7750; PHI:7751; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C3HeB/FeJ,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10725,PHI:7748,UniProt,P9WJR9,GenBank,CCP45921,,,H37Rv,rv3111,,,,,,PHI:7746; PHI:7747; PHI:7749; PHI:7750; PHI:7751; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C3HeB/FeJ,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10726,PHI:7749,UniProt,L7N6B4,GenBank,CCP45922,,,H37Rv,rv3112,,,,,,PHI:7746; PHI:7747; PHI:7748; PHI:7750; PHI:7751; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C3HeB/FeJ,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10727,PHI:7750,UniProt,O05790,GenBank,CCP45923,,,H37Rv,rv3113,,,,,,PHI:7746; PHI:7747; PHI:7748; PHI:7749; PHI:7751; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C3HeB/FeJ,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10728,PHI:7751,UniProt,O05791,GenBank,CCP45924,,,H37Rv,rv3114,,,,,,PHI:7746; PHI:7747; PHI:7748; PHI:7749; PHI:7750; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C3HeB/FeJ,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10729,PHI:7752,UniProt,P96354,GenBank,CCP45925,,,H37Rv,rv3115,,,,,,PHI:7746; PHI:7747; PHI:7748; PHI:7749; PHI:7750; PHI:7751,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C3HeB/FeJ,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10730,PHI:7746,UniProt,P9WJS3,GenBank,CCP45919,,,H37Rv,rv3109,,,,,,PHI:7747; PHI:7748; PHI:7749; PHI:7750; PHI:7751; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10731,PHI:7747,UniProt,Q6MX13,GenBank,CCP45920,,,H37Rv,rv3110,,,,,,PHI:7746; PHI:7748; PHI:7749; PHI:7750; PHI:7751; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10732,PHI:7748,UniProt,P9WJR9,GenBank,CCP45921,,,H37Rv,rv3111,,,,,,PHI:7746; PHI:7747; PHI:7749; PHI:7750; PHI:7751; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10733,PHI:7749,UniProt,L7N6B4,GenBank,CCP45922,,,H37Rv,rv3112,,,,,,PHI:7746; PHI:7747; PHI:7748; PHI:7750; PHI:7751; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10734,PHI:7750,UniProt,O05790,GenBank,CCP45923,,,H37Rv,rv3113,,,,,,PHI:7746; PHI:7747; PHI:7748; PHI:7749; PHI:7751; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10735,PHI:7751,UniProt,O05791,GenBank,CCP45924,,,H37Rv,rv3114,,,,,,PHI:7746; PHI:7747; PHI:7748; PHI:7749; PHI:7750; PHI:7752,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10736,PHI:7752,UniProt,P96354,GenBank,CCP45925,,,H37Rv,rv3115,,,,,,PHI:7746; PHI:7747; PHI:7748; PHI:7749; PHI:7750; PHI:7751,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,involved in hypoxia-responsive molybdenum cofactor biosynthesis,,,hypoxia-responsive molybdenum cofactor biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29176894,PubMed,10.1371/journal.ppat.1006752,PLoS Pathog. 2017 Nov 27;13(11):e1006752,olivier.neyrolles@ipbs.fr,"In vivo, the M. tuberculosis moaA1-D1-null mutant showed impaired survival in hypoxic granulomas in C3HeB/FeJ mice, but not in normoxic lesions in C57BL/6 animals.",F Levillain 2017,2017,7 genes,Levillain-2017-Horizontal acquisition of a hyp,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10737,PHI:7753,UniProt,Q5H5U8,GenBank,AAW73672,,,KACC10331,AnkB (XOO0418),,,,CatB,UniProt: Q5H5U9; GenBank: AAW73671,,347,Xanthomonas oryzae,64187,pv. oryzae strain ZJ173,bacterial leaf blight (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,ankyrin-like protein,,,,reduced virulence,,,,,,,,,,no,phenazine-1-carboxylic acid (PCA); H2O2,phenazine-1-carboxylic acid (PCA): CHEBI:62412; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29180371,PubMed,10.1128/AEM.02145-17,Appl Environ Microbiol. 2017 Nov 27. pii: AEM.02145-17,mgzhou@njau.edu.cn,"Deletion of ankB increased Xoo and Xoc sensitivity to H2O2 and PCA, decreased bacterial biofilm formation, swimming ability and EPS production, and also reduced virulence on rice.",X Pan 2017,2017,2 genes,Pan-2017-The ankyrin-like protein AnkB interac,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10738,PHI:7754,UniProt,G7TM40,GenBank,AEQ98395,,,BLS256,AnkB (XOC_4324),,,,CatB,UniProt: G7TM41; GenBank: AEQ98396,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial leaf streak (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,ankyrin,,,,reduced virulence,,,,,,,,,,no,phenazine-1-carboxylic acid (PCA); H2O2,phenazine-1-carboxylic acid (PCA): CHEBI:62412; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29180371,PubMed,10.1128/AEM.02145-17,Appl Environ Microbiol. 2017 Nov 27. pii: AEM.02145-17,mgzhou@njau.edu.cn,"Deletion of ankB increased Xoo and Xoc sensitivity to H2O2 and PCA, decreased bacterial biofilm formation, swimming ability and EPS production, and also reduced virulence on rice.",X Pan 2017,2017,2 genes,Pan-2017-The ankyrin-like protein AnkB interac,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10739,PHI:7755,UniProt,Q4WV27,GenBank,EAL91549,,,Af293,cofilin (AFUA_5G10570),chromosome 5,,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,actin depolymerizing factor,,,high osmolarity glycerol (HOG) pathway,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; diamide; menadione; paraquat; farnesol; calcofluor white; Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; menadione: CHEBI:28869; paraquat: CHEBI:34905; farnesol: CHEBI:28600; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29170805,PubMed,10.1007/s00294-017-0777-5,Curr Genet. 2017 Nov 23,hanlicdc@163.com,"The cofilin overexpressing strain displayed a slightly different growth phenotype, significantly increased resistance against H2O2and diamide, and increased activation of the high osmolarity glycerol pathway compared to the wild-type strain.",X Jia 2017,2017,1 gene,Jia-2017-Role of actin depolymerizing factor c,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10740,PHI:7755,UniProt,Q4WV27,GenBank,EAL91549,,,Af293,cofilin (AFUA_5G10570),chromosome 5,,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,actin depolymerizing factor,,,high osmolarity glycerol (HOG) pathway,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; diamide; menadione; paraquat; farnesol; calcofluor white; Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; menadione: CHEBI:28869; paraquat: CHEBI:34905; farnesol: CHEBI:28600; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29170805,PubMed,10.1007/s00294-017-0777-5,Curr Genet. 2017 Nov 23,hanlicdc@163.com,"The cofilin overexpressing strain displayed a slightly different growth phenotype, significantly increased resistance against H2O2and diamide, and increased activation of the high osmolarity glycerol pathway compared to the wild-type strain.",X Jia 2017,2017,1 gene,Jia-2017-Role of actin depolymerizing factor c,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10741,PHI:7756,UniProt,E9EJG5,GenBank,EFZ02961,,,ARSEF 23,Mrpct (MAA_00035),,,,,,,568076,Metarhizium robertsii,,,,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,putative phosphocholine cytidylyltransferase,,,cytidine diphosphate (CDP)-choline pathway and phosphatidylethanolamine N-methyltransferase (PEMT) pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29159973,PubMed,10.1111/1462-2920.13998,Environ Microbiol. 2017 Nov 21,cswang@sibs.ac.cn,The results indicated that disruption of Mrpct did not lead to any reduction of totalPC content but impaired fungal virulence andincreased cellular accumulation of triacylglycerol. Deletion of Mrpem reduced PC content and impaired fungal conidiation and infection structure differentiation but did not result in virulence defects.,Y Chen 2017,2017,2 genes,Chen-2017-Diverse effect of phosphatidylcholin,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10742,PHI:7757,UniProt,E9F2M8,GenBank,EFY98317,,,ARSEF 23,Mrpem (MAA_06426),,,,,,,568076,Metarhizium robertsii,,,,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,PE-N-methyltransferase,,,cytidine diphosphate (CDP)-choline pathway and phosphatidylethanolamine N-methyltransferase (PEMT) pathway,unaffected pathogenicity,,yes,yes,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29159973,PubMed,10.1111/1462-2920.13998,Environ Microbiol. 2017 Nov 21,cswang@sibs.ac.cn,The results indicated that disruption of Mrpct did not lead to any reduction of total PC content but impaired fungal virulence andincreased cellular accumulation of triacylglycerol. Deletion of Mrpem reduced PC content and impaired fungal conidiation and infection structure differentiation but did not result invirulence defects.,Y Chen 2017,2017,2 genes,Chen-2017-Diverse effect of phosphatidylcholin,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10743,PHI:7758,UniProt,P14727,GenBank,CAA34257,,,71-21,AvrBs3,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,transcription activator-like (TAL) effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29170655,PubMed,10.3389/fmicb.2017.02180,Front Microbiol. 2017 Nov 9;8:2180,daniela.buettner@genetik.uni-halle.de,"Type 3 secretion (T3S) and translocation of AvrBs3 depended on the N-terminal 10 and 50 amino acids, respectively.",F Scheibner 2017,2017,1 gene,Scheibner-2017-The TAL Effector AvrBs3 from Xa,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10744,PHI:7759,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ece1 (candidalysin),chromosome 4,ece1Δ/Δ+ECE1; ece1Δ/Δ+ECE1Δ184-279,,,,,5476,Candida albicans,,BWP17+cIP30,vulvovaginal candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,vagina,extent of cell elongation protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29109176,PubMed,10.1128/IAI.00645-17,Infect Immun. 2017 Nov 6. pii: IAI.00645-17,julian.naglik@kcl.ac.uk,Candidalysin is required for vaginal immunopathogenesis in vivo and that hypha formation alone is insufficient to elicit immunopathology.,J P Richardson 2017,2017,1 gene,Richardson-2017-Candidalysin drives epithelial,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10745,PHI:7760,UniProt,Q8X4A2,GenBank,AE005295_11,,,EDL933,Stk (ORF: z1444),,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29186483,PubMed,10.1093/infdis/jix160,J Infect Dis. 2017 Nov 27;216(9):1150-1158,geno0109@vip.sina.com,"In EHEC-infected mice, Stk increases serum keratinocyte-derived cytokine levels and hyperactivates the inflammatory response of the colon, intensifying pathological injury of the colon.",T Li 2017,2017,2 genes,Li-2017-Eukaryotic-like Kinase Expression in E,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10746,PHI:7761,,no data found,,,,,,Stx2,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,Shiga toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29186483,PubMed,10.1093/infdis/jix160,J Infect Dis. 2017 Nov 27;216(9):1150-1158,geno0109@vip.sina.com,"In EHEC-infected mice, Stk increases serum keratinocyte-derived cytokine levels and hyperactivates the inflammatory response of the colon, intensifying pathological injury of the colon.",T Li 2017,2017,2 genes,Li-2017-Eukaryotic-like Kinase Expression in E,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10747,PHI:7760,UniProt,Q8X4A2,GenBank,AE005295_11,,,EDL933,Stk (ORF: z1444),,,,,,PHI:7761,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29186483,PubMed,10.1093/infdis/jix160,J Infect Dis. 2017 Nov 27;216(9):1150-1158,geno0109@vip.sina.com,"In EHEC-infected mice, Stk increases serum keratinocyte-derived cytokine levels and hyperactivates the inflammatory response of the colon, intensifying pathological injury of the colon.",T Li 2017,2017,2 genes,Li-2017-Eukaryotic-like Kinase Expression in E,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10748,PHI:7761,,no data found,,,,,,Stx2,,,,,,PHI:7760,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,Shiga toxin 2,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29186483,PubMed,10.1093/infdis/jix160,J Infect Dis. 2017 Nov 27;216(9):1150-1158,geno0109@vip.sina.com,"In EHEC-infected mice, Stk increases serum keratinocyte-derived cytokine levels and hyperactivates the inflammatory response of the colon, intensifying pathological injury of the colon.",T Li 2017,2017,2 genes,Li-2017-Eukaryotic-like Kinase Expression in E,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10749,PHI:7762,UniProt,J9VZ15,GenBank,AFR98701,,,H99,liv7 (cnag_06464),chromosome 13,,,,,,5207,Cryptococcus neoformans,,KN99,disseminated cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6NJ,,,lung; spleen; brain,hypotheticalprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29203547,PubMed,10.1128/IAI.00662-17,Infect Immun. 2017 Dec 4. pii: IAI.00662-17,jessica.brown@path.utah.edu,"The first mutant, liv7Δ, released less glucuronoxylomannan than wild-type cells when capsule is not induced, the second mutant, cnag_00658Δ (ima1Δ), released more exo-GXM under capsule-inducing conditions.",S T Denham 2017,2017,2 genes,Denham-2017-Regulated release of cryptococcal,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10750,PHI:7763,UniProt,J9VEL8,GenBank,AFR92787,,,H99,ima1 (cnag_00658),chromosome 1,,,,,,5207,Cryptococcus neoformans,,KN99,disseminated cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6NJ,,,lung; spleen; brain,inner nuclear membrane protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29203547,PubMed,10.1128/IAI.00662-17,Infect Immun. 2017 Dec 4. pii: IAI.00662-17,jessica.brown@path.utah.edu,"The first mutant, liv7Δ, released less glucuronoxylomannan than wild-type cells when capsule is not induced, the second mutant, cnag_00658Δ (ima1Δ), released more exo-GXM under capsule-inducing conditions.",S T Denham 2017,2017,2 genes,Denham-2017-Regulated release of cryptococcal,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10751,PHI:7764,UniProt,A5U5Y0,GenBank,ABQ74430,,,H37Ra; ATCC 25177,Rv2629,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; kidney; spleen,member of the dosR dormancy regulon and a drug-resistant protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,heterologous expression; altered gene expression / gene regulation: overexpression,,,YVS,29187838,PubMed,10.3389/fmicb.2017.02231,Front Microbiol. 2017 Nov 15;8:2231,zlwqz@163.com,"Overexpression of Rv2629 slightly enhanced the drug resistance of Mycobacterium smegmatis to antibiotics, and increased its survival and pathogenicity in Balb/c mice.",D Liu 2017,2017,1 gene,Liu-2017-Rv2629 Overexpression Delays Mycobact,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10752,PHI:7764,UniProt,A5U5Y0,GenBank,ABQ74430,,,H37Ra; ATCC 25177,Rv2629,,"191A/C mutation (codon 64, Asp to Ala)",,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; kidney; spleen,member of the dosR dormancy regulon and a drug-resistant protein,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene mutation; heterologous expression,,,YVS,29187838,PubMed,10.3389/fmicb.2017.02231,Front Microbiol. 2017 Nov 15;8:2231,zlwqz@163.com,"Overexpression of Rv2629 slightly enhanced the drug resistance of Mycobacterium smegmatis to antibiotics, and increased its survival and pathogenicity in Balb/c mice.",D Liu 2017,2017,1 gene,Liu-2017-Rv2629 Overexpression Delays Mycobact,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10753,PHI:7765,UniProt,A0A0H2ZG25,GenBank,ABJ13403,,,UCBPP-PA14,CcoN4 (PA14_10500),,,,,,PHI:7766; PHI:7767,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,orphan cbb3-type cytochrome oxidase catalytic subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29160206,PubMed,10.7554/eLife.30205,Elife. 2017 Nov 21;6. pii: e30205,LDietrich@ columbia.edu,"CcoN4 colony biofilm development and respiration in the opportunistic pathogen Pseudomonas aeruginosa PA14 and also contributed to the reduction of phenazines, antibiotics that support redox balancing for cells in biofilms, and to virulence in a Caenorhabditis elegans model of infection.",J Jo 2017,2017,3 genes,Jo-2017-An orphan cbb3-type cytochrome oxidase,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10754,PHI:7766,UniProt,A0A0H2Z9C8,GenBank,ABJ10735,,,UCBPP-PA14,CcoN1 (PA14_44370),,,,,,PHI:7765; PHI:7767,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,orphan cbb3-type cytochrome oxidase subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29160206,PubMed,10.7554/eLife.30205,Elife. 2017 Nov 21;6. pii: e30205,LDietrich@ columbia.edu,"CcoN4 colony biofilm development and respiration in the opportunistic pathogen Pseudomonas aeruginosa PA14 and also contributed to the reduction of phenazines, antibiotics that support redox balancing for cells in biofilms, and to virulence in a Caenorhabditis elegans model of infection.",J Jo 2017,2017,3 genes,Jo-2017-An orphan cbb3-type cytochrome oxidase,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10755,PHI:7767,UniProt,A0A0H2Z9B3,GenBank,ABJ10738,,,UCBPP-PA14,CcoN2 (PA14_44340),,,,,,PHI:7765; PHI:7766,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,orphan cbb3-type cytochrome oxidase subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29160206,PubMed,10.7554/eLife.30205,Elife. 2017 Nov 21;6. pii: e30205,LDietrich@ columbia.edu,"CcoN4 colony biofilm development and respiration in the opportunistic pathogen Pseudomonas aeruginosa PA14 and also contributed to the reduction of phenazines, antibiotics that support redox balancing for cells in biofilms, and to virulence in a Caenorhabditis elegans model of infection.",J Jo 2017,2017,3 genes,Jo-2017-An orphan cbb3-type cytochrome oxidase,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10756,PHI:7766,UniProt,A0A0H2Z9C8,GenBank,ABJ10735,,,UCBPP-PA14,CcoN1 (PA14_44370),,,,,,PHI:7767,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,orphan cbb3-type cytochrome oxidase subunit,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29160206,PubMed,10.7554/eLife.30205,Elife. 2017 Nov 21;6. pii: e30205,LDietrich@ columbia.edu,"CcoN4 colony biofilm development and respiration in the opportunistic pathogen Pseudomonas aeruginosa PA14 and also contributed to the reduction of phenazines, antibiotics that support redox balancing for cells in biofilms, and to virulence in a Caenorhabditis elegans model of infection.",J Jo 2017,2017,3 genes,Jo-2017-An orphan cbb3-type cytochrome oxidase,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10757,PHI:7767,UniProt,A0A0H2Z9B3,GenBank,ABJ10738,,,UCBPP-PA14,CcoN2 (PA14_44340),,,,,,PHI:7766,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,orphan cbb3-type cytochrome oxidase subunit,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29160206,PubMed,10.7554/eLife.30205,Elife. 2017 Nov 21;6. pii: e30205,LDietrich@ columbia.edu,"CcoN4 colony biofilm development and respiration in the opportunistic pathogen Pseudomonas aeruginosa PA14 and also contributed to the reduction of phenazines, antibiotics that support redox balancing for cells in biofilms, and to virulence in a Caenorhabditis elegans model of infection.",J Jo 2017,2017,3 genes,Jo-2017-An orphan cbb3-type cytochrome oxidase,BATCH_076,2017-12-01,MC,,,,,,,,,,,,,
,,Record 10758,PHI:7768,UniProt,Q00049,GenBank,NRRL3357,,,,NorA (AflE),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,norsolorinic acid reductase,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29298838,PubMed,10.1074/mcp.RA117.000393,Mol Cell Proteomics. 2018 Jan 3. pii: mcp.RA117.000393,wshyyl@sina.com,"Site-specific mutagenesis and biochemical studies showed that lysine succinylation on the norsolorinic acid reductase NorA (AflE), a key enzyme in aflatoxins biosynthesis, affected the production of sclerotia and aflatoxins biosynthesis in A. flavus.",S Ren 2018,2018,1 gene,Ren-2018-Lysine Succinylation Contributes to A,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10759,PHI:7768,UniProt,Q00049,GenBank,NRRL3357,,,,NorA (AflE),,K370R/K370A,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,norsolorinic acid reductase,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene mutation,,,YVS,29298838,PubMed,10.1074/mcp.RA117.000393,Mol Cell Proteomics. 2018 Jan 3. pii: mcp.RA117.000393,wshyyl@sina.com,"Site-specific mutagenesis and biochemical studies showed that lysine succinylation on the norsolorinic acid reductase NorA (AflE), a key enzyme in aflatoxins biosynthesis, affected the production of sclerotia and aflatoxins biosynthesis in A. flavus.",S Ren 2018,2018,1 gene,Ren-2018-Lysine Succinylation Contributes to A,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10760,PHI:7769,UniProt,Q5ZZB5,GenBank,AAU26203,,,,Ceg4 (Lpg0096),,Ceg4D9A; Ceg4[1-207]; Ceg4[208-397],,,,,446,Legionella pneumophila,,,Legionnaires' disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29301934,PubMed,10.1074/jbc.M117.812727,J Biol Chem. 2018 Jan 4. pii: jbc.M117.812727,alexei.savchenko@ucalgary.ca,Legionella effector Ceg4 which is a bacterial HAD protein tyrosine phosphatase was able to attenuate the MAP kinase responses in both human and yeast cells in vivo.,A T Quaile 2018,2018,1 gene,Quaile-2018-The Legionella pneumophila effecto,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10761,PHI:7770,UniProt,A0A0H6RQV7,GenBank,AKO75949,,,TSY216,leuO,chromosome 1,,,,,PHI:7771; PHI:7772; PHI:7773; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,leucine transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10762,PHI:7771,UniProt,A6P7G9,GenBank,BAF66265,,,NCTC4716,vexB,,,,,,PHI:7770; PHI:7772; PHI:7773; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10763,PHI:7772,UniProt,A6P7H1,GenBank,BAF66267,,,NCTC4716,vexD,,,,,,PHI:7770; PHI:7771; PHI:7773; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10764,PHI:7773,UniProt,A6P7H3,GenBank,BAF66269,,,NCTC4716,vexF,,,,,,PHI:7770; PHI:7771; PHI:7772; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10765,PHI:7774,,no data found,,,,,,vexH,,,,,,PHI:7770; PHI:7771; PHI:7772; PHI:7773; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10766,PHI:7775,,no data found,,,,,,vexK,,,,,,PHI:7770; PHI:7771; PHI:7772; PHI:7773; PHI:7774; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10767,PHI:7776,,no data found,,,,,,vexM,,,,,,PHI:7770; PHI:7771; PHI:7772; PHI:7773; PHI:7774; PHI:7775,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10768,PHI:7777,UniProt,P15795,GenBank,AAF94145,,,N16961,ToxR,,ToxRΔPPD (periplasmic domain),,,,PHI:7771; PHI:7772; PHI:7773; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,"periplasmic sensing system, virulence regulator",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10769,PHI:7771,UniProt,A6P7G9,GenBank,BAF66265,,,NCTC4716,vexB,,,,,,PHI:7777; PHI:7772; PHI:7773; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10770,PHI:7772,UniProt,A6P7H1,GenBank,BAF66267,,,NCTC4716,vexD,,,,,,PHI:7777; PHI:7771; PHI:7773; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10771,PHI:7773,UniProt,A6P7H3,GenBank,BAF66269,,,NCTC4716,vexF,,,,,,PHI:7777; PHI:7771; PHI:7772; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10772,PHI:7774,,no data found,,,,,,vexH,,,,,,PHI:7777; PHI:7771; PHI:7772; PHI:7773; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10773,PHI:7775,,no data found,,,,,,vexK,,,,,,PHI:7777; PHI:7771; PHI:7772; PHI:7773; PHI:7774; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10774,PHI:7776,,no data found,,,,,,vexM,,,,,,PHI:7777; PHI:7771; PHI:7772; PHI:7773; PHI:7774; PHI:7775,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10775,PHI:7771,UniProt,A6P7G9,GenBank,BAF66265,,,NCTC4716,vexB,,,,,,PHI:7772; PHI:7773; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10776,PHI:7772,UniProt,A6P7H1,GenBank,BAF66267,,,NCTC4716,vexD,,,,,,PHI:7771; PHI:7773; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10777,PHI:7773,UniProt,A6P7H3,GenBank,BAF66269,,,NCTC4716,vexF,,,,,,PHI:7771; PHI:7772; PHI:7774; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10778,PHI:7774,,no data found,,,,,,vexH,,,,,,PHI:7771; PHI:7772; PHI:7773; PHI:7775; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10779,PHI:7775,,no data found,,,,,,vexK,,,,,,PHI:7771; PHI:7772; PHI:7773; PHI:7774; PHI:7776,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10780,PHI:7776,,no data found,,,,,,vexM,,,,,,PHI:7771; PHI:7772; PHI:7773; PHI:7774; PHI:7775,666,Vibrio cholerae,,JB58 (Smr ΔlacZ),cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,multidrug efflux transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29304169,PubMed,10.1371/journal.ppat.1006804,PLoS Pathog. 2018 Jan 5;14(1):e1006804,JBina@pitt.edu,ToxR repressed virulence factor production in response to metabolites that are normally effluxed from the cell by the RND transporters.,X R Bina 2018,2018,8 genes,Bina-2018-The Vibrio cholera RND efflux system,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10781,PHI:7778,UniProt,A0A0H2X6Q9,GenBank,AAY48879,,,8004,AmiC1 (XC_1816),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish) cv. Manshenhong,,,leaf,amidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29240286,PubMed,10.1111/mpp.12653,Mol Plant Pathol. 2017 Dec 14,jltang@gxu.edu.cn,AmiC1 and NlpD affected the secretion of type III effector XC3176 and hypersensitive response (HR) induction in planta.,L C Yang 2017,2017,4 genes,Yang-2017-Peptidoglycan hydrolysis mediated by,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10782,PHI:7779,UniProt,B0RTU5,GenBank,CAP51859,,,B100,AmiC2,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish) cv. Manshenhong,,,leaf,amidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29240286,PubMed,10.1111/mpp.12653,Mol Plant Pathol. 2017 Dec 14,jltang@gxu.edu.cn,AmiC1 and NlpD affected the secretion of type III effector XC3176 and hypersensitive response (HR) induction in planta.,L C Yang 2017,2017,4 genes,Yang-2017-Peptidoglycan hydrolysis mediated by,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10783,PHI:7778,UniProt,A0A0H2X6Q9,GenBank,AAY48879,,,8004,AmiC1 (XC_1816),,,,,,PHI:7779,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish) cv. Manshenhong,,,leaf,amidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29240286,PubMed,10.1111/mpp.12653,Mol Plant Pathol. 2017 Dec 14,jltang@gxu.edu.cn,AmiC1 and NlpD affected the secretion of type III effector XC3176 and hypersensitive response (HR) induction in planta.,L C Yang 2017,2017,4 genes,Yang-2017-Peptidoglycan hydrolysis mediated by,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10784,PHI:7779,UniProt,B0RTU5,GenBank,CAP51859,,,B100,AmiC2,,,,,,PHI:7778,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish) cv. Manshenhong,,,leaf,amidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29240286,PubMed,10.1111/mpp.12653,Mol Plant Pathol. 2017 Dec 14,jltang@gxu.edu.cn,AmiC1 and NlpD affected the secretion of type III effector XC3176 and hypersensitive response (HR) induction in planta.,L C Yang 2017,2017,4 genes,Yang-2017-Peptidoglycan hydrolysis mediated by,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10785,PHI:7780,UniProt,A0A0H2X8G8,GenBank,AAY49572,,,8004,NlpD (XC_2522),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish) cv. Manshenhong,,,leaf,LytM family regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29240286,PubMed,10.1111/mpp.12653,Mol Plant Pathol. 2017 Dec 14,jltang@gxu.edu.cn,AmiC1 and NlpD affected the secretion of type III effector XC3176 and hypersensitive response (HR) induction in planta.,L C Yang 2017,2017,4 genes,Yang-2017-Peptidoglycan hydrolysis mediated by,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10786,PHI:7781,UniProt,A0A0H2X2G8,GenBank,AAY47116,,,8004,envC (XC_0022),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish) cv. Manshenhong,,,leaf,LytM family regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29240286,PubMed,10.1111/mpp.12653,Mol Plant Pathol. 2017 Dec 14,jltang@gxu.edu.cn,AmiC1 and NlpD affected the secretion of type III effector XC3176 and hypersensitive response (HR) induction in planta.,L C Yang 2017,2017,4 genes,Yang-2017-Peptidoglycan hydrolysis mediated by,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10787,PHI:7782,,no data found,,,,,,Pmt1,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,mannosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29295913,PubMed,10.1128/mBio.02121-17,MBio. 2018 Jan 2;9(1). pii: e02121-17,rappleye.1@osu.edu,"Histoplasma yeast cells lacking the Pmt1 and Pmt2 protein mannosyltransferases, which catalyzes O-linked mannosylation of proteins, were severely attenuated during infection of mammalian hosts.",A L Garfoot 2018,2018,4 genes,Garfoot-2018-O-Mannosylation of Proteins Enabl,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10788,PHI:7783,,no data found,,,,,,Pmt2,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,mannosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29295913,PubMed,10.1128/mBio.02121-17,MBio. 2018 Jan 2;9(1). pii: e02121-17,rappleye.1@osu.edu,"Histoplasma yeast cells lacking the Pmt1 and Pmt2 protein mannosyltransferases, which catalyzes O-linked mannosylation of proteins, were severely attenuated during infection of mammalian hosts.",A L Garfoot 2018,2018,4 genes,Garfoot-2018-O-Mannosylation of Proteins Enabl,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10789,PHI:7784,,no data found,,,,,,Pmt4,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,mannosyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29295913,PubMed,10.1128/mBio.02121-17,MBio. 2018 Jan 2;9(1). pii: e02121-17,rappleye.1@osu.edu,"Histoplasma yeast cells lacking the Pmt1 and Pmt2 protein mannosyltransferases, which catalyzes O-linked mannosylation of proteins, were severely attenuated during infection of mammalian hosts.",A L Garfoot 2018,2018,4 genes,Garfoot-2018-O-Mannosylation of Proteins Enabl,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10790,PHI:7785,,no data found,,,,,,Mnt1,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,mannosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29295913,PubMed,10.1128/mBio.02121-17,MBio. 2018 Jan 2;9(1). pii: e02121-17,rappleye.1@osu.edu,"Histoplasma yeast cells lacking the Pmt1 and Pmt2 protein mannosyltransferases, which catalyzes O-linked mannosylation of proteins, were severely attenuated during infection of mammalian hosts.",A L Garfoot 2018,2018,4 genes,Garfoot-2018-O-Mannosylation of Proteins Enabl,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10791,PHI:7786,,no data found,GenBank,CAR32588,,,P125109,SEN1005,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,gastroenteritis; bacteremia; enteric fever,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; cecum,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29130383,PubMed,10.1080/21505594.2017.1392428,Virulence. 2017 Nov 13:0,msuar@kiitbiotech.ac.in,ΔSEN1005 displayed significantly reduced entry into cultured epithelial cells as well as uptake by macrophages and failed to cause acute colitis in C57BL/6 mice at day 3 post-infection.,S Das 2017,2017,1 gene,Das-2017-Identification of a novel gene in ROD,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10792,PHI:7787,UniProt,Q88BC5,GenBank,AAO53646,,,DC3000,AldA (PSPTO_0092),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,indole-3-acetaldehyde dehydrogenase,,,indole-3-acetic acid biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,29293681,PubMed,10.1371/journal.ppat.1006811,PLoS Pathog. 2018 Jan 2;14(1):e1006811,kunkel@wustl.edu,"Disruption of aldA and a close homolog, aldB, lead to reduced IAA production in culture and reduced virulence on A. thaliana.",S A McClerklin 2018,2018,2 genes,McClerklin-2018-Indole-3-acetaldehyde dehydrog,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10793,PHI:7788,UniProt,Q882F5,GenBank,AAO56175,,,DC3000,AldB (PSPTO_2673),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,indole-3-acetaldehyde dehydrogenase,,,indole-3-acetic acid biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,29293681,PubMed,10.1371/journal.ppat.1006811,PLoS Pathog. 2018 Jan 2;14(1):e1006811,kunkel@wustl.edu,"Disruption of aldA and a close homolog, aldB, lead to reduced IAA production in culture and reduced virulence on A. thaliana.",S A McClerklin 2018,2018,2 genes,McClerklin-2018-Indole-3-acetaldehyde dehydrog,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10794,PHI:7787,UniProt,Q88BC5,GenBank,AAO53646,,,DC3000,AldA (PSPTO_0092),,,,,,PHI:7788,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,indole-3-acetaldehyde dehydrogenase,,,indole-3-acetic acid biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,29293681,PubMed,10.1371/journal.ppat.1006811,PLoS Pathog. 2018 Jan 2;14(1):e1006811,kunkel@wustl.edu,"Disruption of aldA and a close homolog, aldB, lead to reduced IAA production in culture and reduced virulence on A. thaliana.",S A McClerklin 2018,2018,2 genes,McClerklin-2018-Indole-3-acetaldehyde dehydrog,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10795,PHI:7788,UniProt,Q882F5,GenBank,AAO56175,,,DC3000,AldB (PSPTO_2673),,,,,,PHI:7787,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,indole-3-acetaldehyde dehydrogenase,,,indole-3-acetic acid biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,29293681,PubMed,10.1371/journal.ppat.1006811,PLoS Pathog. 2018 Jan 2;14(1):e1006811,kunkel@wustl.edu,"Disruption of aldA and a close homolog, aldB, lead to reduced IAA production in culture and reduced virulence on A. thaliana.",S A McClerklin 2018,2018,2 genes,McClerklin-2018-Indole-3-acetaldehyde dehydrog,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10796,PHI:7789,UniProt,G7TE26,GenBank,AEQ96351,,,BLS256,Trpr (XOC_2214),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,leaf,transcriptional repressor,,,histidine biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29256829,PubMed,10.1094/PHYTO-09-17-0332-R,Phytopathology. 2017 Dec 19,fqliu20011@sina.com,The his operon in Xoc was not involved in hypersensitive response in non-host tobacco plants.,P Su 2017,2017,3 genes,Su-2017-Insights into the roles of two genes o,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10797,PHI:7790,UniProt,G7TE30,GenBank,AEQ96355,,,BLS256,HisB,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,leaf,bifunctional enzyme implicated in the imidazoleglycerol-phosphate dehydratase activity,,,histidine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29256829,PubMed,10.1094/PHYTO-09-17-0332-R,Phytopathology. 2017 Dec 19,fqliu20011@sina.com,The his operon in Xoc was not involved in hypersensitive response in non-host tobacco plants.,P Su 2017,2017,3 genes,Su-2017-Insights into the roles of two genes o,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10798,PHI:7791,UniProt,G7TM49,GenBank,AEQ98404,,,BLS256,AroE (XOC_4333),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Shanyou 63,,,leaf,shikimate 5-dehydrogenase,,,shikimate pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29256829,PubMed,10.1094/PHYTO-09-17-0332-R,Phytopathology. 2017 Dec 19,fqliu20011@sina.com,The his operon in Xoc was not involved in hypersensitive response in non-host tobacco plants.,P Su 2017,2017,3 genes,Su-2017-Insights into the roles of two genes o,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10799,PHI:7792,UniProt,S8F4S0,GenBank,EPT29682,,,ME49,TgDegP (TGME49_262920),,,,,,,5811,Toxoplasma gondii,383379,RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"serine protease, rhoptry protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29244879,PubMed,10.1371/journal.pone.0189556,PLoS One. 2017 Dec 15;12(12):e0189556,mylebrun@univ-montp2.fr,Genetic disruption of the degP gene did not impact the parasite lytic cycle in vitro but affected virulence in mice.,G Lentini 2017,2017,1 gene,Lentini-2017-Characterization of Toxoplasma De,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10800,PHI:7792,UniProt,S8F4S0,GenBank,EPT29682,,,ME49,TgDegP (TGME49_262920),,,,,,,5811,Toxoplasma gondii,383379,PruΔKu80,,rodents,10090,Mus musculus (related: house mouse),SWR,,,,"serine protease, rhoptry protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29244879,PubMed,10.1371/journal.pone.0189556,PLoS One. 2017 Dec 15;12(12):e0189556,mylebrun@univ-montp2.fr,Genetic disruption of the degP gene did not impact the parasite lytic cycle in vitro but affected virulence in mice.,G Lentini 2017,2017,1 gene,Lentini-2017-Characterization of Toxoplasma De,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10801,PHI:7793,UniProt,G4NKK3,GenBank,EHA45878,,,70-15,Momyo2 (MGG_03060),,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,class II myosin protein,,,,reduced virulence,,yes,yes,,,reduced,,reduced,reduced,no,H2O2; NaCl; calcofluor white; Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28448785,PubMed,10.1080/21505594.2017.1323156,Virulence. 2017 Oct 3;8(7):1335-1354,zhgzhang@njau.edu.cn,"Impairments in conidial germination, glycogen metabolites, tolerance to exogenous stresses and scavenging of host-derived reactive oxygen species were associated with defects on appressorium mediated penetration, and therefore attenuated the virulence of Momyo2 mutants.",M Guo 2017,2017,1 gene,Guo-2017-A Class-II Myosin Is Required for Gro,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10802,PHI:7793,UniProt,G4NKK3,GenBank,EHA45878,,,70-15,Momyo2 (MGG_03060),,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: Barley),cv. Golden Promise,,,leaf,class II myosin protein,,,,reduced virulence,,yes,yes,,,reduced,,reduced,reduced,no,H2O2; NaCl; calcofluor white; Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28448785,PubMed,10.1080/21505594.2017.1323156,Virulence. 2017 Oct 3;8(7):1335-1354,zhgzhang@njau.edu.cn,"Impairments in conidial germination, glycogen metabolites, tolerance to exogenous stresses and scavenging of host-derived reactive oxygen species were associated with defects on appressorium mediated penetration, and therefore attenuated the virulence of Momyo2 mutants.",M Guo 2017,2017,1 gene,Guo-2017-A Class-II Myosin Is Required for Gro,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10803,PHI:7794,,no data found,GenBank,CAZ51128,,,SC84,SSUSC84_0350,,,,,,,1307,Streptococcus suis,,serotype 2,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene mutation; gene complementation,,,YVS,27315343,PubMed,10.1080/21505594.2016.1201256,Virulence. 2017 Jan 2;8(1):53-65,beiwc@mail.hzau.edu.cn,"The Δnox strain exhibited impaired growth under oxidative stress conditions, suggesting that NADH oxidase was involved in oxidative stress tolerance.",C Zheng 2016,2016,4 genes,Zheng-2016-Contribution of NADH oxidase to oxi,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10804,PHI:7795,,no data found,GenBank,CAZ51426,,,SC84,nox,,,,,,,1307,Streptococcus suis,,serotype 2,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,NADH oxidase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene mutation; gene complementation,,,YVS,27315343,PubMed,10.1080/21505594.2016.1201256,Virulence. 2017 Jan 2;8(1):53-65,beiwc@mail.hzau.edu.cn,"The Δnox strain exhibited impaired growth under oxidative stress conditions, suggesting that NADH oxidase was involved in oxidative stress tolerance.",C Zheng 2016,2016,4 genes,Zheng-2016-Contribution of NADH oxidase to oxi,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10805,PHI:7796,,no data found,GenBank,CAZ52022,,,SC84,tpx,,,,,,,1307,Streptococcus suis,,serotype 2,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,thiol peroxidase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene mutation; gene complementation,,,YVS,27315343,PubMed,10.1080/21505594.2016.1201256,Virulence. 2017 Jan 2;8(1):53-65,beiwc@mail.hzau.edu.cn,"The Δnox strain exhibited impaired growth under oxidative stress conditions, suggesting that NADH oxidase was involved in oxidative stress tolerance.",C Zheng 2016,2016,4 genes,Zheng-2016-Contribution of NADH oxidase to oxi,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10806,PHI:7797,,no data found,GenBank,CAZ52023,,,SC84,copA,,,,,,,1307,Streptococcus suis,,serotype 2,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,copper-transporting ATPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene mutation; gene complementation,,,YVS,27315343,PubMed,10.1080/21505594.2016.1201256,Virulence. 2017 Jan 2;8(1):53-65,beiwc@mail.hzau.edu.cn,"The Δnox strain exhibited impaired growth under oxidative stress conditions, suggesting that NADH oxidase was involved in oxidative stress tolerance.",C Zheng 2016,2016,4 genes,Zheng-2016-Contribution of NADH oxidase to oxi,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10807,PHI:7795,,no data found,GenBank,CAZ51426,,,SC84,nox,,,,,,,1307,Streptococcus suis,,serotype 2,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,brain; heart; lung,NADH oxidase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene mutation; gene complementation,,,YVS,27315343,PubMed,10.1080/21505594.2016.1201256,Virulence. 2017 Jan 2;8(1):53-65,beiwc@mail.hzau.edu.cn,"The Δnox strain exhibited impaired growth under oxidative stress conditions, suggesting that NADH oxidase was involved in oxidative stress tolerance.",C Zheng 2016,2016,4 genes,Zheng-2016-Contribution of NADH oxidase to oxi,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10808,PHI:7798,UniProt,A0A0H2ZPU8,GenBank,EDT92177,,,D39,spd1836,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; pleural cavity; lung; blood,membrane occupation and recognition nexus (MORN) repeats-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,Contribution of OM001 operon to pneumococcal virulence was solely due to spd1836.,Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10809,PHI:7799,UniProt,A0A0H2ZQ64,GenBank,EDT92184,,,D39,spd1837,,Δspd1837 C8S,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; pleural cavity; lung; blood,low molecular weight protein tyrosine phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,Contribution of OM001 operon to pneumococcal virulence was solely due to spd1836.,Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10810,PHI:7799,UniProt,A0A0H2ZQ64,GenBank,EDT92184,,,D39,spd1837,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; pleural cavity; lung; blood,low molecular weight protein tyrosine phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,Contribution of OM001 operon to pneumococcal virulence was solely due to spd1836.,Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10811,PHI:7800,UniProt,A0A0H2ZP20,GenBank,ABJ54629,,,D39,spd1838,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; pleural cavity; lung; blood,translocase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,Contribution of OM001 operon to pneumococcal virulence was solely due to spd1836.,Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10812,PHI:7798,UniProt,A0A0H2ZPU8,GenBank,EDT92177,,,D39,spd1836,,,,,,PHI:7799; PHI:7800,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; pleural cavity; lung; blood,membrane occupation and recognition nexus (MORN) repeats-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,Contribution of OM001 operon to pneumococcal virulence was solely due to spd1836.,Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10813,PHI:7799,UniProt,A0A0H2ZQ64,GenBank,EDT92184,,,D39,spd1837,,,,,,PHI:7798; PHI:7800,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; pleural cavity; lung; blood,low molecular weight protein tyrosine phosphatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,Contribution of OM001 operon to pneumococcal virulence was solely due to spd1836.,Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10814,PHI:7800,UniProt,A0A0H2ZP20,GenBank,ABJ54629,,,D39,spd1838,,,,,,PHI:7798; PHI:7799,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; pleural cavity; lung; blood,translocase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,Contribution of OM001 operon to pneumococcal virulence was solely due to spd1836.,Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10815,PHI:7798,UniProt,A0A0H2ZPU8,GenBank,EDT92177,,,D39,spd1836,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,saliva,membrane occupation and recognition nexus (MORN) repeats-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,"The results suggested that deletion in spd1836 and spd1838 reduced pneumococcal survival in human saliva during conditions that mimic transmission (at 25 °C without CO2), but not during conditions that mimic in-host carriage (37 °C with CO2).",Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10816,PHI:7799,UniProt,A0A0H2ZQ64,GenBank,EDT92184,,,D39,spd1837,,Δspd1837 C8S,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,saliva,low molecular weight protein tyrosine phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,"The results suggested that deletion in spd1836 and spd1838 reduced pneumococcal survival in human saliva during conditions that mimic transmission (at 25 °C without CO2), but not during conditions that mimic in-host carriage (37 °C with CO2).",Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10817,PHI:7799,UniProt,A0A0H2ZQ64,GenBank,EDT92184,,,D39,spd1837,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,saliva,low molecular weight protein tyrosine phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,"The results suggested that deletion in spd1836 and spd1838 reduced pneumococcal survival in human saliva during conditions that mimic transmission (at 25 °C without CO2), but not during conditions that mimic in-host carriage (37 °C with CO2).",Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10818,PHI:7800,UniProt,A0A0H2ZP20,GenBank,ABJ54629,,,D39,spd1838,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,saliva,translocase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,"The results suggested that deletion in spd1836 and spd1838 reduced pneumococcal survival in human saliva during conditions that mimic transmission (at 25 °C without CO2), but not during conditions that mimic in-host carriage (37 °C with CO2).",Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10819,PHI:7798,UniProt,A0A0H2ZPU8,GenBank,EDT92177,,,D39,spd1836,,,,,,PHI:7799; PHI:7800,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,saliva,membrane occupation and recognition nexus (MORN) repeats-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,"The results suggested that deletion in spd1836 and spd1838 reduced pneumococcal survival in human saliva during conditions that mimic transmission (at 25 °C without CO2), but not during conditions that mimic in-host carriage (37 °C with CO2).",Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10820,PHI:7799,UniProt,A0A0H2ZQ64,GenBank,EDT92184,,,D39,spd1837,,,,,,PHI:7798; PHI:7800,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,saliva,low molecular weight protein tyrosine phosphatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,"The results suggested that deletion in spd1836 and spd1838 reduced pneumococcal survival in human saliva during conditions that mimic transmission (at 25 °C without CO2), but not during conditions that mimic in-host carriage (37 °C with CO2).",Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10821,PHI:7800,UniProt,A0A0H2ZP20,GenBank,ABJ54629,,,D39,spd1838,,,,,,PHI:7798; PHI:7799,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,saliva,translocase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29293606,PubMed,10.1371/journal.pone.0190402,PLoS One. 2018 Jan 2;13(1):e0190402,alistair.standish@adelaide.edu.au,"The results suggested that deletion in spd1836 and spd1838 reduced pneumococcal survival in human saliva during conditions that mimic transmission (at 25 °C without CO2), but not during conditions that mimic in-host carriage (37 °C with CO2).",Z Ahmad 2018,2018,3 genes,Ahmad-2018-Role of Streptococcus pneumoniae OM,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10822,PHI:7801,UniProt,Q87ZP2,GenBank,AAO56860,,,DC3000,cvsS (PSPTO_3382),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,"Ca2+ induced two-component system, histidine kinase",,,,reduced virulence,,,,,,,,,,no,CaCl2,CaCl2: CHEBI:3312,,,,,gene deletion: full,,,YVS,29263098,PubMed,10.1128/JB.00538-17,J Bacteriol. 2017 Dec 20. pii: JB.00538-17,Melanie.filiatrault@ars.usda.gov,"Phenotypic analysis determined that CvsSR inversely regulated biofilm formation, swarming motility, and cellulose production in a Ca2+-dependent manner.",M R Fishman 2017,2017,2 genes,Fishman-2017-The Ca(2+) induced two-component,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10823,PHI:7802,UniProt,Q87ZP1,GenBank,AAO56861,,,DC3000,cvsR (PSPTO_3383 ),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,"Ca2+ induced two-component system, response regulator",,,,reduced virulence,,,,,,,,,,no,CaCl2,CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,29263098,PubMed,10.1128/JB.00538-17,J Bacteriol. 2017 Dec 20. pii: JB.00538-17,Melanie.filiatrault@ars.usda.gov,"Phenotypic analysis determined that CvsSR inversely regulated biofilm formation, swarming motility, and cellulose production in a Ca2+-dependent manner.",M R Fishman 2017,2017,2 genes,Fishman-2017-The Ca(2+) induced two-component,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10824,PHI:7801,UniProt,Q87ZP2,GenBank,AAO56860,,,DC3000,cvsS (PSPTO_3382),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,"Ca2+ induced two-component system, histidine kinase",,,,reduced virulence,,,,,,,,,,no,CaCl2,CaCl2: CHEBI:3312,,,,,gene deletion: full,,,YVS,29263098,PubMed,10.1128/JB.00538-17,J Bacteriol. 2017 Dec 20. pii: JB.00538-17,Melanie.filiatrault@ars.usda.gov,"Phenotypic analysis determined that CvsSR inversely regulated biofilm formation, swarming motility, and cellulose production in a Ca2+-dependent manner.",M R Fishman 2017,2017,2 genes,Fishman-2017-The Ca(2+) induced two-component,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10825,PHI:7802,UniProt,Q87ZP1,GenBank,AAO56861,,,DC3000,cvsR (PSPTO_3383 ),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,"Ca2+ induced two-component system, response regulator",,,,reduced virulence,,,,,,,,,,no,CaCl2,CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,29263098,PubMed,10.1128/JB.00538-17,J Bacteriol. 2017 Dec 20. pii: JB.00538-17,Melanie.filiatrault@ars.usda.gov,"Phenotypic analysis determined that CvsSR inversely regulated biofilm formation, swarming motility, and cellulose production in a Ca2+-dependent manner.",M R Fishman 2017,2017,2 genes,Fishman-2017-The Ca(2+) induced two-component,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10826,PHI:7803,UniProt,Q8YAR0,GenBank,CAC98271,,,EGD-e,esxA (lmo0056),,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27723420,PubMed,10.1080/21505594.2016.1244589,Virulence. 2017 Aug 18;8(6):993-1004,didier@ibmc.up.pt,L. monocytogenes ESX-1 secretion system and its substrates were dispensable for bacterial invasion and intracellular multiplication ineukaryotic cell lines.,J Pinheiro 2016,2016,3 genes,Pinheiro-2016-Listeria monocytogenes encodes a,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10827,PHI:7804,UniProt,Q8YAQ4,GenBank,CAC98278,,,EGD-e,esxB (lmo0063),,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27723420,PubMed,10.1080/21505594.2016.1244589,Virulence. 2017 Aug 18;8(6):993-1004,didier@ibmc.up.pt,L. monocytogenes ESX-1 secretion system and its substrates were dispensable for bacterial invasion and intracellular multiplication ineukaryotic cell lines.,J Pinheiro 2016,2016,3 genes,Pinheiro-2016-Listeria monocytogenes encodes a,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10828,PHI:7805,UniProt,Q8YAQ5,GenBank,CAC98276,,,EGD-e,essC (lmo0061),,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,integral membrane protein essential for the secretion machinery,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27723420,PubMed,10.1080/21505594.2016.1244589,Virulence. 2017 Aug 18;8(6):993-1004,didier@ibmc.up.pt,L. monocytogenes ESX-1 secretion system and its substrates were dispensable for bacterial invasion and intracellular multiplication ineukaryotic cell lines.,J Pinheiro 2016,2016,3 genes,Pinheiro-2016-Listeria monocytogenes encodes a,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10829,PHI:7803,UniProt,Q8YAR0,GenBank,CAC98271,,,EGD-e,esxA (lmo0056),,+esxA,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,27723420,PubMed,10.1080/21505594.2016.1244589,Virulence. 2017 Aug 18;8(6):993-1004,didier@ibmc.up.pt,L. monocytogenes ESX-1 secretion system and its substrates were dispensable for bacterial invasion and intracellular multiplication ineukaryotic cell lines.,J Pinheiro 2016,2016,3 genes,Pinheiro-2016-Listeria monocytogenes encodes a,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10830,PHI:7806,UniProt,G7SZR2,GenBank,AET56041,,,RKS5078,cigR,,,,,,,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),Hy-line white,,,liver; spleen,type III secretion system 2 effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27163262,PubMed,10.1080/03079457.2016.1187708,Avian Pathol. 2016 Oct;45(5):569-75,jiao@yzu.edu.cn,Deletion of cigR significantly decreased biofilm formation and significantly increased virulence.,J Yin 2016,2016,1 gene,Yin-2016-Construction and characterization of,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10831,PHI:7807,,no data found,,,,,,arg1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,inositol polyphosphate kinase,,,,loss of pathogenicity,,,,,,,,reduced,,no,Congo red; calcofluor white; SDS; caffeine; tunicamycin; DTT,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; caffeine: CHEBI:27732; tunicamycin: CHEBI:29699; DTT: CHEBI:42170,,,,,gene mutation; gene complementation,,,YVS,28976803,PubMed,10.1080/21505594.2017.1385692,Virulence. 2017 Nov 17;8(8):1833-1848,julianne.djordjevic@sydney.edu.au,The more deleterious arg1Δ phenotype correlated with a higher rate of arg1Δ phagocytosis than that of kcs1Δ by human peripheral blood monocytes and rapid arg1Δ clearance from lung in a mouse model.,C Li 2017,2017,2 genes,Li-2017-IP3-4 kinase Arg1 regulates cell wall,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10832,PHI:7808,,no data found,,,,,,kcs1,,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,inositol polyphosphate kinase,,,,reduced virulence,,,,,,,,reduced,,no,Congo red; calcofluor white; SDS; caffeine; tunicamycin; DTT,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; caffeine: CHEBI:27732; tunicamycin: CHEBI:29699; DTT: CHEBI:42170,,,,,gene mutation,,,YVS,28976803,PubMed,10.1080/21505594.2017.1385692,Virulence. 2017 Nov 17;8(8):1833-1848,julianne.djordjevic@sydney.edu.au,The more deleterious arg1Δ phenotype correlated with a higher rate of arg1Δ phagocytosis than that of kcs1Δ by human peripheral blood monocytes and rapid arg1Δ clearance from lung in a mouse model.,C Li 2017,2017,2 genes,Li-2017-IP3-4 kinase Arg1 regulates cell wall,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10833,PHI:7809,UniProt,A3M2U3,GenBank,ABO11237,,,ATCC 17978,adeN,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,TetR type regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,28436748,PubMed,10.1080/21505594.2017.1322240,Virulence. 2017 Oct 3;8(7):1316-1334,prashi2k@gmail.com,Biofilm levels were abrogated in the adeN knockout when compared with the wild type and complemented strain of adeN knockout.,R Saranathan 2017,2017,1 gene,Saranathan-2017-Disruption of tetR type regula,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10834,PHI:7810,UniProt,C5MB73,GenBank,EER32890,,,MYA-3404,CaTpk1 (CTRG_03315),,,,,,PHI:7811,5482,Candida tropicalis,294747,ATCC MYA-3404,oral mucosa infection; genital tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,catalytic subunit of PKA,,,,loss of pathogenicity,,,,yes,,,,wild type,,no,micafungin; anidulafungin; posaconazole; sodium dodecyl sulfate [SDS]; dithiothreitol [DTT]),"micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; posaconazole,  sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170",,,,,gene disruption; gene complementation,,,YVS,29254431,PubMed,10.1080/21505594.2017.1414132,Virulence. 2017 Dec 19:0,ychen28@ntu.edu.tw,"Results suggested that Tpk1 is involved in cell wall integrity and drug tolerance and the tpk2/tpk2 mutants, which have no protein kinase A activity, have reduced hyphal growth and adhesion.",C J Lin 2017,2017,2 genes,Lin-2017-Protein kinase A governs growth and v,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10835,PHI:7811,UniProt,C5M7A4,GenBank,EER34874,,,MYA-3404,CaTpk2 (CTRG_01736),,,,,,PHI:7810,5482,Candida tropicalis,294747,ATCC MYA-3404,oral mucosa infection; genital tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,catalytic subunit of PKA,,,,loss of pathogenicity,,,,yes,,,,wild type,,no,micafungin; anidulafungin; posaconazole; sodium dodecyl sulfate [SDS]; dithiothreitol [DTT]),"micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; posaconazole,  sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170",,,,,gene disruption; gene complementation,,,YVS,29254431,PubMed,10.1080/21505594.2017.1414132,Virulence. 2017 Dec 19:0,ychen28@ntu.edu.tw,"Results suggested that Tpk1 is involved in cell wall integrity and drug tolerance and the tpk2/tpk2 mutants, which have no protein kinase A activity, have reduced hyphal growth and adhesion.",C J Lin 2017,2017,2 genes,Lin-2017-Protein kinase A governs growth and v,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10836,PHI:7810,UniProt,C5MB73,GenBank,EER32890,,,MYA-3404,CaTpk1 (CTRG_03315),,,,,,,5482,Candida tropicalis,294747,ATCC MYA-3404,oral mucosa infection; genital tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,catalytic subunit of PKA,,,,unaffected pathogenicity,,,,yes,,,,wild type,,no,micafungin; anidulafungin; posaconazole; sodium dodecyl sulfate [SDS]; dithiothreitol [DTT]),"micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; posaconazole,  sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170",,,,,gene disruption; gene complementation,,,YVS,29254431,PubMed,10.1080/21505594.2017.1414132,Virulence. 2017 Dec 19:0,ychen28@ntu.edu.tw,"Results suggested that Tpk1 is involved in cell wall integrity and drug tolerance and the tpk2/tpk2 mutants, which have no protein kinase A activity, have reduced hyphal growth and adhesion.",C J Lin 2017,2017,2 genes,Lin-2017-Protein kinase A governs growth and v,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10837,PHI:7811,UniProt,C5M7A4,GenBank,EER34874,,,MYA-3404,CaTpk2 (CTRG_01736),,,,,,,5482,Candida tropicalis,294747,ATCC MYA-3404,oral mucosa infection; genital tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,catalytic subunit of PKA,,,,unaffected pathogenicity,,,,yes,,,,wild type,,no,micafungin; anidulafungin; posaconazole; sodium dodecyl sulfate [SDS]; dithiothreitol [DTT]),"micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; posaconazole,  sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170",,,,,gene disruption; gene complementation,,,YVS,29254431,PubMed,10.1080/21505594.2017.1414132,Virulence. 2017 Dec 19:0,ychen28@ntu.edu.tw,"Results suggested that Tpk1 is involved in cell wall integrity and drug tolerance and the tpk2/tpk2 mutants, which have no protein kinase A activity, have reduced hyphal growth and adhesion.",C J Lin 2017,2017,2 genes,Lin-2017-Protein kinase A governs growth and v,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10838,PHI:7812,UniProt,J9VJ31,GenBank,AFR93401,,,H99,Mgt1 (CNAG_03901),,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,Mg transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29243387,PubMed,10.1002/mbo3.564,Microbiologyopen. 2017 Dec 15,dingchen@mail.neu.edu.cn,"Repressing the expression of MGT2-induced capsule, which resulted in an increased fungal burden in the lungs.",C H Suo 2017,2017,3 genes,Suo-2017-Investigation of Cryptococcus neoform,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10839,PHI:7813,UniProt,J9VTH6,GenBank,AFR96726,,,H99,Mgt2 (CNAG_03502),,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain,Mg transporter,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation; chemical complementation,,,YVS,29243387,PubMed,10.1002/mbo3.564,Microbiologyopen. 2017 Dec 15,dingchen@mail.neu.edu.cn,"Repressing the expression of MGT2-induced capsule, which resulted in an increased fungal burden in the lungs.",C H Suo 2017,2017,3 genes,Suo-2017-Investigation of Cryptococcus neoform,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10840,PHI:7813,UniProt,J9VTH6,GenBank,AFR96726,,,H99,Mgt2 (CNAG_03502),,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,Mg transporter,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation; chemical complementation,,,YVS,29243387,PubMed,10.1002/mbo3.564,Microbiologyopen. 2017 Dec 15,dingchen@mail.neu.edu.cn,"Repressing the expression of MGT2-induced capsule, which resulted in an increased fungal burden in the lungs.",C H Suo 2017,2017,3 genes,Suo-2017-Investigation of Cryptococcus neoform,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10841,PHI:7814,UniProt,J9VDP1,GenBank,AFR92148,,,H99,Mgt3 (CNAG_00010),,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,Mg transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29243387,PubMed,10.1002/mbo3.564,Microbiologyopen. 2017 Dec 15,dingchen@mail.neu.edu.cn,"Repressing the expression of MGT2-induced capsule, which resulted in an increased fungal burden in the lungs.",C H Suo 2017,2017,3 genes,Suo-2017-Investigation of Cryptococcus neoform,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10842,PHI:7815,UniProt,A0A0A2VP56,GenBank,KGQ07950,,,D1-5,Mst2,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone acetyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,Congo red; SDS; hydroxyurea; methyl methanesulfonate (MMS); menadione; sorbitol; H2O2; NaCl,Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; menadione: CHEBI:28869; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29275430,PubMed,10.1007/s00253-017-8703-9,Appl Microbiol Biotechnol. 2018 Feb;102(3):1343-1355,mgfeng@zju.edu.cn,"The Δmst2 conidia suffered slower germination, decreased hydrophobicity, attenuated virulence, and reduced thermotolerance and UV-B resistance.",J J Wang 2017,2017,1 gene,Wang-2017-The histone acetyltransferase Mst2 s,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10843,PHI:7816,UniProt,A0A0H2ZDM9,GenBank,ABJ12377,,,UCBPP-PA14,PA14_23430 (hepP),,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),BW54,,,,heparinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29246112,PubMed,10.1186/s12866-017-1141-0,BMC Microbiol. 2017 Dec 16;17(1):233,abdul.hamood@ttuhsc.edu,The heparinase encoded by hepP is a potential virulence factor for PA14 as HepP influences pellicle formation as well as biofilm development by PA14 and the protein is required for full virulence in the C. elegans model of slow killing.,N Dzvova 2017,2017,2 genes,Dzvova-2017-Isolation and characterization of,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10844,PHI:7817,UniProt,A0A0H2ZDI1,GenBank,ABJ12378,,,UCBPP-PA14,PA14_23420 (zbdP),,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),BW54,,,,putative zinc-binding dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29246112,PubMed,10.1186/s12866-017-1141-0,BMC Microbiol. 2017 Dec 16;17(1):233,abdul.hamood@ttuhsc.edu,The heparinase encoded by hepP is a potential virulence factor for PA14 as HepP influences pellicle formation as well as biofilm development by PA14 and the protein is required for full virulence in the C. elegans model of slow killing.,N Dzvova 2017,2017,2 genes,Dzvova-2017-Isolation and characterization of,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10845,PHI:7818,UniProt,A6QFG2,GenBank,BAF67094,,,Newman,MnhA1,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Hsd:ND4,,,kidney,multi-subunit Na+/H+ (Mnh) antiporter,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl; KCl,NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,29263099,PubMed,10.1128/JB.00611-17,J Bacteriol. 2017 Dec 20. pii: JB.00611-17,terry.krulwich@mssm.edu,"Deletion of the mnhA1 gene led to a major loss of S. aureus virulence in mice, while deletion of mnhA2 led to no change in virulence.",M Vaish 2017,2017,2 genes,Vaish-2017-Roles of Staphylococcus aureus Mnh1,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10846,PHI:7819,UniProt,A6QET3,GenBank,BAF66865,,,Newman,MnhA2,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Hsd:ND4,,,kidney,multi-subunit Na+/H+ (Mnh) antiporter,,,,unaffected pathogenicity,,,,,,,,reduced; aberrant,,no,NaCl; KCl,NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,29263099,PubMed,10.1128/JB.00611-17,J Bacteriol. 2017 Dec 20. pii: JB.00611-17,terry.krulwich@mssm.edu,"Deletion of the mnhA1 gene led to a major loss of S. aureus virulence in mice, while deletion of mnhA2 led to no change in virulence.",M Vaish 2017,2017,2 genes,Vaish-2017-Roles of Staphylococcus aureus Mnh1,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10847,PHI:7820,UniProt,H7C7Q3,GenBank,AAC66722,,,B31,oppD (bb0334),,heterodimeric nucleotide-binding domain (NBD),,,,PHI:7821,139,Borreliella burgdorferi,,B31 5A18 NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,skin; ear; tibiotarsal joint; bladder; heart,oligopepeptide (Opp) transporter that drives transport by hydrolyzing ATP,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation; chemical complementation,,,YVS,29259089,PubMed,10.1128/mBio.02047-17,MBio. 2017 Dec 19;8(6). pii: e02047-17,JRadolf@uchc.edu,"The NBD mutant was avirulent by needle inoculation, but infectivity was partially restored by oral administration of IPTG to infected mice.",A M Groshong 2017,2017,2 genes,Groshong-2017-Peptide Uptake Is Essential for,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10848,PHI:7821,UniProt,H7C7L2,GenBank,AAC66721,,,B31,oppF (bb0335),,heterodimeric nucleotide-binding domain (NBD),,,,PHI:7820,139,Borreliella burgdorferi,,B31 5A18 NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,skin; ear; tibiotarsal joint; bladder; heart,oligopepeptide (Opp) transporter that drives transport by hydrolyzing ATP,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation; chemical complementation,,,YVS,29259089,PubMed,10.1128/mBio.02047-17,MBio. 2017 Dec 19;8(6). pii: e02047-17,JRadolf@uchc.edu,"The NBD mutant was avirulent by needle inoculation, but infectivity was partially restored by oral administration of IPTG to infected mice.",A M Groshong 2017,2017,2 genes,Groshong-2017-Peptide Uptake Is Essential for,BATCH_077,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10849,PHI:7822,UniProt,Q9PL71,GenBank,AAF39108,,,Nigg,tc0237,,,,,,,83560,Chlamydia muridarum,,Nigg3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,small intestine; cecum; colon,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28584162,PubMed,10.1128/IAI.00321-17,Infect Immun. 2017 Jul 19;85(8). pii: e00321-17,Zhongg@UTHSCSA.edu,"C. muridarum with mutations in chromosomal genes tc0237 and/or tc0668 was defective in spreading to the mouse gastrointestinal tract, which correlated with its attenuated pathogenicity in the upper genital tract.",L Shao 2017,2017,2 genes,Shao-2017-Chlamydia muridarum with mutations i,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10850,PHI:7823,UniProt,Q9PK05,GenBank,AAF39490,,,Nigg,tc0668,,,,,,,83560,Chlamydia muridarum,,Nigg3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,small intestine; cecum; colon,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28584162,PubMed,10.1128/IAI.00321-17,Infect Immun. 2017 Jul 19;85(8). pii: e00321-17,Zhongg@UTHSCSA.edu,"C. muridarum with mutations in chromosomal genes tc0237 and/or tc0668 was defective in spreading to the mouse gastrointestinal tract, which correlated with its attenuated pathogenicity in the upper genital tract.",L Shao 2017,2017,2 genes,Shao-2017-Chlamydia muridarum with mutations i,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10851,PHI:7822,UniProt,Q9PL71,GenBank,AAF39108,,,Nigg,tc0237,,,,,,PHI:7823,83560,Chlamydia muridarum,,Nigg3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,small intestine; cecum; colon,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28584162,PubMed,10.1128/IAI.00321-17,Infect Immun. 2017 Jul 19;85(8). pii: e00321-17,Zhongg@UTHSCSA.edu,"C. muridarum with mutations in chromosomal genes tc0237 and/or tc0668 was defective in spreading to the mouse gastrointestinal tract, which correlated with its attenuated pathogenicity in the upper genital tract.",L Shao 2017,2017,2 genes,Shao-2017-Chlamydia muridarum with mutations i,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10852,PHI:7823,UniProt,Q9PK05,GenBank,AAF39490,,,Nigg,tc0668,,,,,,PHI:7822,83560,Chlamydia muridarum,,Nigg3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,small intestine; cecum; colon,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28584162,PubMed,10.1128/IAI.00321-17,Infect Immun. 2017 Jul 19;85(8). pii: e00321-17,Zhongg@UTHSCSA.edu,"C. muridarum with mutations in chromosomal genes tc0237 and/or tc0668 was defective in spreading to the mouse gastrointestinal tract, which correlated with its attenuated pathogenicity in the upper genital tract.",L Shao 2017,2017,2 genes,Shao-2017-Chlamydia muridarum with mutations i,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10853,PHI:7824,UniProt,Q4UX47,GenBank,AAY48376,,,8004,HpaP (XC_1307),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,regulatory protein with ATPase and phosphatase activity,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); phenol; NaCl; H2O2; CoCl2; CdCl2,sodium dodecyl sulfate (SDS): CHEBI:8984; phenol: CHEBI:15882; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CoCl2: CHEBI:35696; CdCl2: CHEBI:35456,,,,,gene deletion: full; gene complementation,,,YVS,29345052,PubMed,10.1111/1462-2920.14046,Environ Microbiol. 2018 Jan 18,lugt@gxu.edu.cn,Clean deletion of hpaP demonstrated reduced virulence and HR (hypersensitive response) induction of Xcc and alterations in cell motility and stress tolerance.,P Cui 2018,2018,1 gene,"Cui-2018-HpaP, a novel regulatory protein with",BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10854,PHI:7824,UniProt,Q4UX47,GenBank,AAY48376,,,8004,HpaP (XC_1307),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,regulatory protein with ATPase and phosphatase activity,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); phenol; NaCl; H2O2; CoCl2; CdCl2,sodium dodecyl sulfate (SDS): CHEBI:8984; phenol: CHEBI:15882; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CoCl2: CHEBI:35696; CdCl2: CHEBI:35456,,,,,gene deletion: full; gene complementation,,,YVS,29345052,PubMed,10.1111/1462-2920.14046,Environ Microbiol. 2018 Jan 18,lugt@gxu.edu.cn,Clean deletion of hpaP demonstrated reduced virulence and HR (hypersensitive response) induction of Xcc and alterations in cell motility and stress tolerance.,P Cui 2018,2018,1 gene,"Cui-2018-HpaP, a novel regulatory protein with",BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10855,PHI:7825,,no data found,GenBank,ABO10717,,,ATCC 17978,A1S_0242 (feoA),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,involved in iron uptake,,,,reduced virulence,,,,,,,,,,no,"2,2′-bipyridil; paraquat","2,2′-bipyridil: CHEBI:30351; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,29334313,PubMed,10.1080/21505594.2017.1420451,Virulence. 2018 Jan 15:0,Margarita.Poza.Dominguez@sergas.es,"A1S_0242 gene (feoA) from A. baumannii ATCC 17978 strain, which is involved in iron uptake and that was found as over-expressed during the course of a pneumonia infection, plays a role in adhesion, biofilm formation and resistance to oxidative stress.",L Alvarez-Fraga 2018,2018,2 genes,Alvarez-Fraga-2018-Pneumonia infection in mice,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10856,PHI:7826,,no data found,GenBank,ABS90275,,,ATCC 17978,A1S_3850,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,involved in iron uptake,,,,reduced virulence,,,,,,,,,,no,"2,2′-bipyridil; paraquat","2,2′-bipyridil: CHEBI:30351; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,29334313,PubMed,10.1080/21505594.2017.1420451,Virulence. 2018 Jan 15:0,Margarita.Poza.Dominguez@sergas.es,"A1S_0242 gene (feoA) from A. baumannii ATCC 17978 strain, which is involved in iron uptake and that was found as over-expressed during the course of a pneumonia infection, plays a role in adhesion, biofilm formation and resistance to oxidative stress.",L Alvarez-Fraga 2018,2018,2 genes,Alvarez-Fraga-2018-Pneumonia infection in mice,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10857,PHI:7825,,no data found,GenBank,ABO10717,,,ATCC 17978,A1S_0242 (feoA),,,,,,PHI:7826,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,involved in iron uptake,,,,reduced virulence,,,,,,,,,,no,"2,2′-bipyridil; paraquat","2,2′-bipyridil: CHEBI:30351; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,29334313,PubMed,10.1080/21505594.2017.1420451,Virulence. 2018 Jan 15:0,Margarita.Poza.Dominguez@sergas.es,"A1S_0242 gene (feoA) from A. baumannii ATCC 17978 strain, which is involved in iron uptake and that was found as over-expressed during the course of a pneumonia infection, plays a role in adhesion, biofilm formation and resistance to oxidative stress.",L Alvarez-Fraga 2018,2018,2 genes,Alvarez-Fraga-2018-Pneumonia infection in mice,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10858,PHI:7826,,no data found,GenBank,ABS90275,,,ATCC 17978,A1S_3850,,,,,,PHI:7825,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,involved in iron uptake,,,,reduced virulence,,,,,,,,,,no,"2,2′-bipyridil; paraquat","2,2′-bipyridil: CHEBI:30351; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,29334313,PubMed,10.1080/21505594.2017.1420451,Virulence. 2018 Jan 15:0,Margarita.Poza.Dominguez@sergas.es,"A1S_0242 gene (feoA) from A. baumannii ATCC 17978 strain, which is involved in iron uptake and that was found as over-expressed during the course of a pneumonia infection, plays a role in adhesion, biofilm formation and resistance to oxidative stress.",L Alvarez-Fraga 2018,2018,2 genes,Alvarez-Fraga-2018-Pneumonia infection in mice,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10859,PHI:7825,,no data found,GenBank,ABO10717,,,ATCC 17978,A1S_0242 (feoA),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; blood,involved in iron uptake,,,,reduced virulence,,,,,,,,,,no,"2,2′-bipyridil; paraquat","2,2′-bipyridil: CHEBI:30351; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,29334313,PubMed,10.1080/21505594.2017.1420451,Virulence. 2018 Jan 15:0,Margarita.Poza.Dominguez@sergas.es,"A1S_0242 gene (feoA) from A. baumannii ATCC 17978 strain, which is involved in iron uptake and that was found as over-expressed during the course of a pneumonia infection, plays a role in adhesion, biofilm formation and resistance to oxidative stress.",L Alvarez-Fraga 2018,2018,2 genes,Alvarez-Fraga-2018-Pneumonia infection in mice,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10860,PHI:7827,UniProt,A0A0H2ZCZ2,GenBank,ABJ12138,,,UCBPP-PA14,AtvR (PA14_26570),,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; liver,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28533471,PubMed,10.1128/IAI.00207-17,Infect Immun. 2017 Jul 19;85(8). pii: e00207-17,baldini@iq.usp.br,Macrophage infection with the atvR mutant strain resulted in higher levels of tumor necrosis factor alpha secretion as well as increased bacterial clearance compared to those for macrophages infected with the wild-type strain.,G H Kaihami 2017,2017,1 gene,Kaihami-2017-The atypical response regulator A,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10861,PHI:7828,UniProt,J9VNE4,GenBank,CNAG_02036,,,H99,Uxt1,,,,,,PHI:7829,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; spleen; brain,UDP-xyltransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346417,PubMed,10.1371/journal.ppat.1006765,PLoS Pathog. 2018 Jan 18;14(1):e1006765,doering@wustl.edu,"Uxt1 and Uxt2 were required for xylose incorporation into capsule and protein; they are also necessary for C. neoformans to cause disease in mice, although surprisingly not for fungal viability in the context of infection.",L X Li 2018,2018,2 genes,Li-2018-Xylose donor transport is critical for,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10862,PHI:7829,UniProt,J9VNC0,GenBank,CNAG_03695,,,H99,Uxt2,,,,,,PHI:7828,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; spleen; brain,UDP-xyltransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346417,PubMed,10.1371/journal.ppat.1006765,PLoS Pathog. 2018 Jan 18;14(1):e1006765,doering@wustl.edu,"Uxt1 and Uxt2 were required for xylose incorporation into capsule and protein; they are also necessary for C. neoformans to cause disease in mice, although surprisingly not for fungal viability in the context of infection.",L X Li 2018,2018,2 genes,Li-2018-Xylose donor transport is critical for,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10863,PHI:7828,UniProt,J9VNE4,GenBank,CNAG_02036,,,H99,Uxt1,,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; spleen; brain,UDP-xyltransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346417,PubMed,10.1371/journal.ppat.1006765,PLoS Pathog. 2018 Jan 18;14(1):e1006765,doering@wustl.edu,"Uxt1 and Uxt2 were required for xylose incorporation into capsule and protein; they are also necessary for C. neoformans to cause disease in mice, although surprisingly not for fungal viability in the context of infection.",L X Li 2018,2018,2 genes,Li-2018-Xylose donor transport is critical for,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10864,PHI:7829,UniProt,J9VNC0,GenBank,CNAG_03695,,,H99,Uxt2,,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; spleen; brain,UDP-xyltransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346417,PubMed,10.1371/journal.ppat.1006765,PLoS Pathog. 2018 Jan 18;14(1):e1006765,doering@wustl.edu,"Uxt1 and Uxt2 were required for xylose incorporation into capsule and protein; they are also necessary for C. neoformans to cause disease in mice, although surprisingly not for fungal viability in the context of infection.",L X Li 2018,2018,2 genes,Li-2018-Xylose donor transport is critical for,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10865,PHI:7828,UniProt,J9VNE4,GenBank,CNAG_02036,,,H99,Uxt1,,,,,,PHI:7829,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; brain,UDP-xyltransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346417,PubMed,10.1371/journal.ppat.1006765,PLoS Pathog. 2018 Jan 18;14(1):e1006765,doering@wustl.edu,"Uxt1 and Uxt2 were required for xylose incorporation into capsule and protein; they are also necessary for C. neoformans to cause disease in mice, although surprisingly not for fungal viability in the context of infection.",L X Li 2018,2018,2 genes,Li-2018-Xylose donor transport is critical for,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10866,PHI:7829,UniProt,J9VNC0,GenBank,CNAG_03695,,,H99,Uxt2,,,,,,PHI:7828,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; brain,UDP-xyltransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346417,PubMed,10.1371/journal.ppat.1006765,PLoS Pathog. 2018 Jan 18;14(1):e1006765,doering@wustl.edu,"Uxt1 and Uxt2 were required for xylose incorporation into capsule and protein; they are also necessary for C. neoformans to cause disease in mice, although surprisingly not for fungal viability in the context of infection.",L X Li 2018,2018,2 genes,Li-2018-Xylose donor transport is critical for,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10867,PHI:7828,UniProt,J9VNE4,GenBank,CNAG_02036,,,H99,Uxt1,,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; brain,UDP-xyltransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346417,PubMed,10.1371/journal.ppat.1006765,PLoS Pathog. 2018 Jan 18;14(1):e1006765,doering@wustl.edu,"Uxt1 and Uxt2 were required for xylose incorporation into capsule and protein; they are also necessary for C. neoformans to cause disease in mice, although surprisingly not for fungal viability in the context of infection.",L X Li 2018,2018,2 genes,Li-2018-Xylose donor transport is critical for,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10868,PHI:7829,UniProt,J9VNC0,GenBank,CNAG_03695,,,H99,Uxt2,,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; brain,UDP-xyltransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346417,PubMed,10.1371/journal.ppat.1006765,PLoS Pathog. 2018 Jan 18;14(1):e1006765,doering@wustl.edu,"Uxt1 and Uxt2 were required for xylose incorporation into capsule and protein; they are also necessary for C. neoformans to cause disease in mice, although surprisingly not for fungal viability in the context of infection.",L X Li 2018,2018,2 genes,Li-2018-Xylose donor transport is critical for,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10869,PHI:7830,UniProt,Q2G2S6,GenBank,ABD31031,,,NCTC 8325,PrsA,,,,,,,1280,Staphylococcus aureus,,HG001,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"membrane-anchored lipoprotein, foldase",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29334195,PubMed,10.1002/pmic.201700195,Proteomics. 2018 Jan 15,luckywu@mail.cgu.edu.tw,"PrsA deficiency can enhance bacterial auto-aggregation and increase the adhesion ability of S. aureus to human lung epithelial cells, moreover, mice infected with PrsA-deficient S. aureus had a better survival rate compared with those infected with the wild-type.",M H Lin 2018,2018,1 gene,Lin-2018-Exoproteome Profiling Reveals the Inv,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10870,PHI:7831,,no data found,GenBank,ATI05617,,,M12,fecA,,,,,,,562,Escherichia coli,1392858,M12,mastitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,mammary gland; spleen,ferric dicitrate transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29101196,PubMed,10.1128/AEM.02190-17,Appl Environ Microbiol. 2018 Jan 2;84(2). pii: e02190-17,david_erickson@byu.edu,Targeted deletion of fecA from strain M12 caused attenuation in G. mellonella larvae and reduced growth in unpasteurized cow's milk and lactating mouse mammary glands.,M A Olson 2018,2018,3 genes,Olson-2018-Genome-Wide Identification of Fitne,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10871,PHI:7831,,no data found,GenBank,ATI05617,,,M12,fecA,,,,,,,562,Escherichia coli,1392858,M12,mastitis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ferric dicitrate transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29101196,PubMed,10.1128/AEM.02190-17,Appl Environ Microbiol. 2018 Jan 2;84(2). pii: e02190-17,david_erickson@byu.edu,Targeted deletion of fecA from strain M12 caused attenuation in G. mellonella larvae and reduced growth in unpasteurized cow's milk and lactating mouse mammary glands.,M A Olson 2018,2018,3 genes,Olson-2018-Genome-Wide Identification of Fitne,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10872,PHI:7832,UniProt,P42217,GenBank,CAA52658,,,K5,kpsC,,,,,,PHI:7833,562,Escherichia coli,1392858,M12,mastitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,mammary gland; spleen,capsule biosynthesis,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29101196,PubMed,10.1128/AEM.02190-17,Appl Environ Microbiol. 2018 Jan 2;84(2). pii: e02190-17,david_erickson@byu.edu,Targeted deletion of fecA from strain M12 caused attenuation in G. mellonella larvae and reduced growth in unpasteurized cow's milk and lactating mouse mammary glands.,M A Olson 2018,2018,3 genes,Olson-2018-Genome-Wide Identification of Fitne,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10873,PHI:7833,UniProt,P42218,GenBank,CAA52659,,,K5,kpsS,,,,,,PHI:7832,562,Escherichia coli,1392858,M12,mastitis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,capsule biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29101196,PubMed,10.1128/AEM.02190-17,Appl Environ Microbiol. 2018 Jan 2;84(2). pii: e02190-17,david_erickson@byu.edu,Targeted deletion of fecA from strain M12 caused attenuation in G. mellonella larvae and reduced growth in unpasteurized cow's milk and lactating mouse mammary glands.,M A Olson 2018,2018,3 genes,Olson-2018-Genome-Wide Identification of Fitne,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10874,PHI:7834,,no data found,GenBank,CCE35745,,,UT205,MmpL11,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,cell wall lipid transporter,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28507063,PubMed,10.1128/IAI.00131-17,Infect Immun. 2017 Jul 19;85(8). pii: e00131-17,purdyg@ohsu.edu,M. tuberculosis mmpL11 mutants had altered biofilms associated with lower levels of mycolic acid wax ester and long-chain triacylglycerols than those for wild-type bacteria.,C C Wright 2017,2017,1 gene,Wright-2017-The Mycobacterium tuberculosis Mmp,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10875,PHI:7834,,no data found,GenBank,CCE35745,,,UT205,MmpL11,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),,,,granuloma cell,cell wall lipid transporter,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28507063,PubMed,10.1128/IAI.00131-17,Infect Immun. 2017 Jul 19;85(8). pii: e00131-17,purdyg@ohsu.edu,M. tuberculosis mmpL11 mutants had altered biofilms associated with lower levels of mycolic acid wax ester and long-chain triacylglycerols than those for wild-type bacteria. granuloma generated from peripheral blood mononuclear cells,C C Wright 2017,2017,1 gene,Wright-2017-The Mycobacterium tuberculosis Mmp,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10876,PHI:7835,UniProt,J9W340,GenBank,AFR98590,,,H99,Cgp1 (CNAG_06352 ),chromosome 13,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,fungal meningitis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,microtubule-associated CAP-glycine protein,,,,reduced virulence,,,,,,,reduced,,,no,sodium dodecyl sulfate (SDS); amphotericin B (AMB); sorbitol; NaCl,sodium dodecyl sulfate (SDS): CHEBI:8984; amphotericin B: CHEBI:2682; sorbitol: CHEBI:30911; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29338542,PubMed,10.1080/21505594.2017.1423189,Virulence. 2018 Jan 17:0,ysbahn@yonsei.ac.kr,"CAP-Gly protein, Cgp1, has pleotropic roles in regulating growth, stress responses, differentiation, and virulence in C. neoformans.",L L Wang 2018,2018,1 gene,Wang-2018-The novel microtubule-associated CAP,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10877,PHI:7836,,no data found,GenBank,ANN28576,,,FORC_017,flp,chromosome 2,,,,,,672,Vibrio vulnificus,1219061,CDC B9629,vibriosis,bivalves,6565,Crassostrea virginica (related: eastern oyster),,,,,tight adherence (tad) pilus,,,,reduced virulence,,,,,,,,increased; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29235706,PubMed,10.1111/1462-2920.14025,Environ Microbiol. 2017 Dec 13,drowemag@indiana.edu,Deletion of the associated pilin (flp) decreased biofilm and aggregate formation.,M Pu 2017,2017,1 gene,Pu-2017-A conserved tad pilus promotes Vibrio,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10878,PHI:7837,UniProt,P09983,GenBank,AAA23975,,,,hlyA,,,,,,,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,pore forming toxin alpha-hemolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10879,PHI:7838,UniProt,Q46962,GenBank,AAA85196,,,A70.1,cnf1,,,,,,,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,cytotoxic necrotizing factor type 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10880,PHI:7839,UniProt,Q9LCC7,GenBank,BAA93674,,,,usp,,,,,,,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,uropathogenic specific protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10881,PHI:7840,UniProt,Q0P7J3,GenBank,ANK35455,,,ECONIH2,clbC,,,,,,PHI:7841; PHI:7842; PHI:7843; PHI:7844,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10882,PHI:7841,UniProt,Q0P7J4,GenBank,ANK32693,,,ECONIH2,clbD,,,,,,PHI:7840; PHI:7842; PHI:7843; PHI:7844,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,3-hydroxybutyryl-CoA dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10883,PHI:7842,UniProt,Q0P7J5,GenBank,ANK35454,,,ECONIH2,clbE,,,,,,PHI:7840; PHI:7841; PHI:7843; PHI:7844,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,alanine-phosphoribitol ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10884,PHI:7843,UniProt,Q0P7J6,GenBank,ANK32692,,,ECONIH2,clbF,,,,,,PHI:7840; PHI:7841; PHI:7842; PHI:7844,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,acyl-CoA dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10885,PHI:7844,UniProt,Q0P7J7,GenBank,ANK32691,,,ECONIH2,clbG,,,,,,PHI:7840; PHI:7841; PHI:7842; PHI:7843,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,transacylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10886,PHI:7845,UniProt,Q9K2Y6,GenBank,AAF71893,,,C664-1992,fliC,,,,,,,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,flagellin protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10887,PHI:7846,UniProt,P08191,GenBank,CAA29156,,,,fimH,,,,,,,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,type 1 pilus-associated adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10888,PHI:7847,UniProt,P13720,GenBank,AAA24285,,,,papG,,,,,,,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,adhesin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10889,PHI:7845,UniProt,Q9K2Y6,GenBank,AAF71893,,,C664-1992,fliC,,,,,,PHI:7846,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,flagellin protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10890,PHI:7846,UniProt,P08191,GenBank,CAA29156,,,,fimH,,,,,,PHI:7845,562,Escherichia coli,340197,F11,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; stomach,type 1 pilus-associated mannose-binding adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29311232,PubMed,10.1128/IAI.00746-17,Infect Immun. 2018 Jan 8. pii: IAI.00746-17,mulvey@path.utah.edu,The mutant missing the type 1 pilus-associated adhesin FimH displayed somewhat reduced persistence within the gut.,C W Russell 2018,2018,11 genes,Russell-2018-Context-dependent Requirements fo,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10891,PHI:7848,UniProt,Q0PC56,GenBank,AF038283_1,,,CH5,CdtA,,,,,,PHI:7849; PHI:7850,197,Campylobacter jejuni,,CS2,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,gut,cytolethal distending toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,29330183,PubMed,10.1128/AEM.01893-17,Appl Environ Microbiol. 2018 Jan 12. pii: AEM.01893-17,ksen@uw.edu,Chicks infected with CS2 had the normal gene cluster suggesting that colonization of C. jejuni was not affected by the cdt gene cluster.,K Sen 2018,2018,3 genes,Sen-2018-Campylobacter jejuni Colonization in,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10892,PHI:7849,UniProt,Q0PC57,GenBank,CAL34251,,,NCTC 11168,CdtB,,,,,,PHI:7848; PHI:7850,197,Campylobacter jejuni,,CS2,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,gut,cytolethal distending toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,29330183,PubMed,10.1128/AEM.01893-17,Appl Environ Microbiol. 2018 Jan 12. pii: AEM.01893-17,ksen@uw.edu,Chicks infected with CS2 had the normal gene cluster suggesting that colonization of C. jejuni was not affected by the cdt gene cluster.,K Sen 2018,2018,3 genes,Sen-2018-Campylobacter jejuni Colonization in,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10893,PHI:7850,UniProt,Q0PC58,GenBank,CAL34250,,,NCTC 11168,CdtC,,,,,,PHI:7849; PHI:7850,197,Campylobacter jejuni,,CS2,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,gut,cytolethal distending toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,29330183,PubMed,10.1128/AEM.01893-17,Appl Environ Microbiol. 2018 Jan 12. pii: AEM.01893-17,ksen@uw.edu,Chicks infected with CS2 had the normal gene cluster suggesting that colonization of C. jejuni was not affected by the cdt gene cluster.,K Sen 2018,2018,3 genes,Sen-2018-Campylobacter jejuni Colonization in,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10894,PHI:7851,,no data found,,,,,,RS14730,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,taurine ATP-binding transport system component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10895,PHI:7852,,no data found,,,,,,RS16805,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,aldehyde dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10896,PHI:7853,,no data found,,,,,,RS17040,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,major facilitator superfamily permease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10897,PHI:7854,,no data found,,,,,,RS17045,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,dihydroxy-acid dehydratase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10898,PHI:7855,,no data found,,,,,,RS17035,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,fumarylacetoacetate hydrolase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10899,PHI:7856,,no data found,,,,,,RS17030,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,aldehyde dehydrogenase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10900,PHI:7857,,no data found,,,,,,RS14735,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10901,PHI:7858,,no data found,,,,,,RS14740,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10902,PHI:7859,,no data found,,,,,,RS17050,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10903,PHI:7860,UniProt,A3M1G3,GenBank,ABO10757,,,ATCC 17978,RpoB,,aminoacid substitution at either Gln522 or Ser540,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,beta-subunit of the RNA polymerase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10904,PHI:7851,,no data found,,,,,,RS14730,,,,,,,470,Acinetobacter baumannii,,MAR002,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,taurine ATP-binding transport system component,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10905,PHI:7852,,no data found,,,,,,RS16805,,,,,,,470,Acinetobacter baumannii,,MAR002,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,aldehyde dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10906,PHI:7853,,no data found,,,,,,RS17040,,,,,,,470,Acinetobacter baumannii,,MAR002,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,major facilitator superfamily permease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10907,PHI:7854,,no data found,,,,,,RS17045,,,,,,,470,Acinetobacter baumannii,,MAR002,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,dihydroxy-acid dehydratase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10908,PHI:7855,,no data found,,,,,,RS17035,,,,,,,470,Acinetobacter baumannii,,MAR002,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,fumarylacetoacetate hydrolase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10909,PHI:7856,,no data found,,,,,,RS17030,,,,,,,470,Acinetobacter baumannii,,MAR002,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,aldehyde dehydrogenase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene disruption,,,YVS,28507065,PubMed,10.1128/IAI.00327-17,Infect Immun. 2017 Jul 19;85(8). pii: e00327-17,jesus.aranda@uab.cat,"The construction of knockout mutants in each of the six downregulated genes revealed a significant reduction in the surface-associated motility and virulence of four of them in the A. baumannii ATCC 17978 strain, as well as in the virulent clinical isolate MAR002.",M Perez-Varela 2017,2017,10 genes,Perez-Varela-2017-Mutants in the beta-subunit,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10910,PHI:7861,UniProt,A0A0U0WTG6,GenBank,CPT98415,,,PAP061,eccB4 (MAB_3759c),,,,,,,36809,Mycobacteroides abscessus,,subsp. massiliense strain CIP 104536T,pulmonary infection; cutaneo-mucous infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,ESX-4 type VII secretion system component,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29343644,PubMed,10.1073/pnas.1713195115,Proc Natl Acad Sci U S A. 2018 Jan 17. pii: 201713195,jean-louis.herrmann@aphp.fr,The mutant was less efficient at blocking phagosomal acidification than its parental strain and the mutant failed to damage phagosomes and showed reduced signs of phagosome-to-cytosol contact.,L Laencina 2018,2018,1 gene,Laencina-2018-Identification of genes required,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10911,PHI:7861,UniProt,A0A0U0WTG6,GenBank,CPT98415,,,PAP061,eccB4 (MAB_3759c),,,,,,,36809,Mycobacteroides abscessus,,subsp. massiliense strain CIP 104536T,pulmonary infection; cutaneo-mucous infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,ESX-4 type VII secretion system component,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29343644,PubMed,10.1073/pnas.1713195115,Proc Natl Acad Sci U S A. 2018 Jan 17. pii: 201713195,jean-louis.herrmann@aphp.fr,The mutant was less efficient at blocking phagosomal acidification than its parental strain and the mutant failed to damage phagosomes and showed reduced signs of phagosome-to-cytosol contact.,L Laencina 2018,2018,1 gene,Laencina-2018-Identification of genes required,BATCH_078,2018-01-01,MC,,,,,,,,,,,,,
,,Record 10912,PHI:7862,UniProt,A0A0E4D570,GenBank,CQR89556,,,CHI-32,vgrG,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,T6SS component (valine-glycine repeat G),,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29394284,PubMed,10.1371/journal.pone.0192288,PLoS One. 2018 Feb 2;13(2):e0192288,yvys119@zju.edu.cn,VgrG gene was not implicated in A. baumannii biofilm formation and also the cell adhesion ability of the wild type cells on BEAS-2b human alveolar epithelial cells was stronger than that of the knockout strain,J Wang 2018,2018,1 gene,Wang-2018-The role of the type VI secretion sy,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10913,PHI:7863,UniProt,G8B6D4,GenBank,CCE40015,,,CDC317,CPAR2_100540,,,,,,,5480,Candida parapsilosis,578454,CDC317,mycosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,transcriptional activator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29358719,PubMed,10.1038/s41598-018-19453-4,Sci Rep. 2018 Jan 22;8(1):1346,gacsera@gmail.com,"During infection, CPAR2_100540 was responsible for nutrient acquisition, CPAR2_200390 for cell wall assembly and morphology switching and CPAR2_303700 for fungal viability.",R Tóth 2018,2018,3 genes,Toth-2018-Investigation of Candida parapsilosi,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10914,PHI:7863,UniProt,G8B6D4,GenBank,CCE40015,,,CDC317,CPAR2_100540,,,,,,,5480,Candida parapsilosis,578454,CDC317,mycosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; kidney,transcriptional activator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29358719,PubMed,10.1038/s41598-018-19453-4,Sci Rep. 2018 Jan 22;8(1):1346,gacsera@gmail.com,"During infection, CPAR2_100540 was responsible for nutrient acquisition, CPAR2_200390 for cell wall assembly and morphology switching and CPAR2_303700 for fungal viability.",R Tóth 2018,2018,3 genes,Toth-2018-Investigation of Candida parapsilosi,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10915,PHI:7864,UniProt,G8BEK7,GenBank,CCE42396,,,CDC317,CPAR2_200390,,,,,,,5480,Candida parapsilosis,578454,CDC317,mycosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,calcoflour white,calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,29358719,PubMed,10.1038/s41598-018-19453-4,Sci Rep. 2018 Jan 22;8(1):1346,gacsera@gmail.com,"During infection, CPAR2_100540 was responsible for nutrient acquisition, CPAR2_200390 for cell wall assembly and morphology switching and CPAR2_303700 for fungal viability.",R Tóth 2018,2018,3 genes,Toth-2018-Investigation of Candida parapsilosi,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10916,PHI:7864,UniProt,G8BEK7,GenBank,CCE42396,,,CDC317,CPAR2_200390,,,,,,,5480,Candida parapsilosis,578454,CDC317,mycosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,hypothetical protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,calcoflour white,calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,29358719,PubMed,10.1038/s41598-018-19453-4,Sci Rep. 2018 Jan 22;8(1):1346,gacsera@gmail.com,"During infection, CPAR2_100540 was responsible for nutrient acquisition, CPAR2_200390 for cell wall assembly and morphology switching and CPAR2_303700 for fungal viability.",R Tóth 2018,2018,3 genes,Toth-2018-Investigation of Candida parapsilosi,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10917,PHI:7865,UniProt,G8B9S9,GenBank,CCE41381,,,CDC317,CPAR2_303700,,,,,,,5480,Candida parapsilosis,578454,CDC317,mycosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29358719,PubMed,10.1038/s41598-018-19453-4,Sci Rep. 2018 Jan 22;8(1):1346,gacsera@gmail.com,"During infection, CPAR2_100540 was responsible for nutrient acquisition, CPAR2_200390 for cell wall assembly and morphology switching and CPAR2_303700 for fungal viability.",R Tóth 2018,2018,3 genes,Toth-2018-Investigation of Candida parapsilosi,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10918,PHI:7865,UniProt,G8B9S9,GenBank,CCE41381,,,CDC317,CPAR2_303700,,,,,,,5480,Candida parapsilosis,578454,CDC317,mycosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; kidney,hypothetical protein,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29358719,PubMed,10.1038/s41598-018-19453-4,Sci Rep. 2018 Jan 22;8(1):1346,gacsera@gmail.com,"During infection, CPAR2_100540 was responsible for nutrient acquisition, CPAR2_200390 for cell wall assembly and morphology switching and CPAR2_303700 for fungal viability.",R Tóth 2018,2018,3 genes,Toth-2018-Investigation of Candida parapsilosi,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10919,PHI:7866,UniProt,A0A0U5BRC2,GenBank,CEG15248,,,,Lon,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,leaf,protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29362236,PubMed,10.1128/mBio.02146-17,MBio. 2018 Jan 23;9(1). pii: e02146-17,nianwang@ufl.edu,Lon negatively regulates bacterial virulence by repressing T3SS gene transcription wherein phosphorylation of Lon protease is required for bacterial virulence and HR induction.,Zhou X 2018,2018,1 gene,Zhou-2018-A Phosphorylation Switch on Lon Prot,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10920,PHI:7866,UniProt,A0A0U5BRC2,GenBank,CEG15248,,,,Lon,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,leaf,protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29362236,PubMed,10.1128/mBio.02146-17,MBio. 2018 Jan 23;9(1). pii: e02146-17,nianwang@ufl.edu,Lon negatively regulates bacterial virulence by repressing T3SS gene transcription wherein phosphorylation of Lon protease is required for bacterial virulence and HR induction.,Zhou X 2018,2018,1 gene,Zhou-2018-A Phosphorylation Switch on Lon Prot,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10921,PHI:7866,UniProt,A0A0U5BRC2,GenBank,CEG15248,,,,Lon,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,leaf,protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29362236,PubMed,10.1128/mBio.02146-17,MBio. 2018 Jan 23;9(1). pii: e02146-17,nianwang@ufl.edu,Lon negatively regulates bacterial virulence by repressing T3SS gene transcription wherein phosphorylation of Lon protease is required for bacterial virulence and HR induction.,Zhou X 2018,2018,1 gene,Zhou-2018-A Phosphorylation Switch on Lon Prot,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10922,PHI:7866,UniProt,A0A0U5BRC2,GenBank,CEG15248,,,,Lon,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,leaf,protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29362236,PubMed,10.1128/mBio.02146-17,MBio. 2018 Jan 23;9(1). pii: e02146-17,nianwang@ufl.edu,Lon negatively regulates bacterial virulence by repressing T3SS gene transcription wherein phosphorylation of Lon protease is required for bacterial virulence and HR induction.,Zhou X 2018,2018,1 gene,Zhou-2018-A Phosphorylation Switch on Lon Prot,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10923,PHI:7866,UniProt,A0A0U5BRC2,GenBank,CEG15248,,,,Lon,,LonS654A,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,leaf,protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29362236,PubMed,10.1128/mBio.02146-17,MBio. 2018 Jan 23;9(1). pii: e02146-17,nianwang@ufl.edu,Lon negatively regulates bacterial virulence by repressing T3SS gene transcription wherein phosphorylation of Lon protease is required for bacterial virulence and HR induction.,Zhou X 2018,2018,1 gene,Zhou-2018-A Phosphorylation Switch on Lon Prot,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10924,PHI:7866,UniProt,A0A0U5BRC2,GenBank,CEG15248,,,,Lon,,LonS654E or LonS654D,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,leaf,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29362236,PubMed,10.1128/mBio.02146-17,MBio. 2018 Jan 23;9(1). pii: e02146-17,nianwang@ufl.edu,Lon negatively regulates bacterial virulence by repressing T3SS gene transcription wherein phosphorylation of Lon protease is required for bacterial virulence and HR induction.,Zhou X 2018,2018,1 gene,Zhou-2018-A Phosphorylation Switch on Lon Prot,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10925,PHI:7867,UniProt,J9VX38,GenBank,AFR97946,,,H99,had1 (CNAG_01744),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,HAD-like hydrolase,,,calcineurin pathway,reduced virulence,,,,,,,,,,no,calcofluor white; Congo red (CR); dithiothreitol; SDS; KCl; NaCl,calcofluor white: CHEBI:50011; Congo red (CR): CHEBI:34653; dithiothreitol: CHEBI:42170; SDS: CHEBI:8984; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29233914,PubMed,10.1534/g3.117.300444,G3 (Bethesda). 2018 Feb 2;8(2):643-652,phsoo97@knu.ac.kr,"The calcineurin-Crz1 pathway and Had1 controled growth at high temperature, stress response, and virulence via parallel pathways.",W H Jung 2018,2018,2 genes,Jung-2018-Had1 Is Required for Cell Wall Integ,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10926,PHI:7868,UniProt,J9VE33,GenBank,AFR92293,,,H99,crz1,chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,zinc finger transcription factor,,,calcineurin pathway,reduced virulence,,,,,,,,,,no,calcofluor white; Congo red (CR); dithiothreitol; SDS; KCl; NaCl,calcofluor white: CHEBI:50011; Congo red (CR): CHEBI:34653; dithiothreitol: CHEBI:42170; SDS: CHEBI:8984; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,29233914,PubMed,10.1534/g3.117.300444,G3 (Bethesda). 2018 Feb 2;8(2):643-652,phsoo97@knu.ac.kr,"The calcineurin-Crz1 pathway and Had1 controled growth at high temperature, stress response, and virulence via parallel pathways.",W H Jung 2018,2018,2 genes,Jung-2018-Had1 Is Required for Cell Wall Integ,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10927,PHI:7867,UniProt,J9VX38,GenBank,AFR97946,,,H99,had1 (CNAG_01744),chromosome 11,,,,,PHI:7868,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,HAD-like hydrolase,,,calcineurin pathway,reduced virulence,,,,,,,,,,no,calcofluor white; Congo red (CR); dithiothreitol; SDS; KCl; NaCl,calcofluor white: CHEBI:50011; Congo red (CR): CHEBI:34653; dithiothreitol: CHEBI:42170; SDS: CHEBI:8984; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,29233914,PubMed,10.1534/g3.117.300444,G3 (Bethesda). 2018 Feb 2;8(2):643-652,phsoo97@knu.ac.kr,"The calcineurin-Crz1 pathway and Had1 controled growth at high temperature, stress response, and virulence via parallel pathways.",W H Jung 2018,2018,2 genes,Jung-2018-Had1 Is Required for Cell Wall Integ,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10928,PHI:7868,UniProt,J9VE33,GenBank,AFR92293,,,H99,crz1,chromosome 1,,,,,PHI:7867,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,zinc finger transcription factor,,,calcineurin pathway,reduced virulence,,,,,,,,,,no,calcofluor white; Congo red (CR); dithiothreitol; SDS; KCl; NaCl,calcofluor white: CHEBI:50011; Congo red (CR): CHEBI:34653; dithiothreitol: CHEBI:42170; SDS: CHEBI:8984; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,29233914,PubMed,10.1534/g3.117.300444,G3 (Bethesda). 2018 Feb 2;8(2):643-652,phsoo97@knu.ac.kr,"The calcineurin-Crz1 pathway and Had1 controled growth at high temperature, stress response, and virulence via parallel pathways.",W H Jung 2018,2018,2 genes,Jung-2018-Had1 Is Required for Cell Wall Integ,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10929,PHI:7869,,no data found,,,,,,PstMCM1-1,,,,PstSTE12; PstbE1,UniProt: A0A1Z2WU64; GenBank: ASB16860; UniProt: no data found,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,MADS-box transcription factor,,,,reduced virulence,yes,,,yes,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29393562,PubMed,10.1111/1462-2920.14054,Environ Microbiol. 2018 Feb 2,kangzs@nwsuaf.edu.cn,"Knock down of PstMCM1-1 resulted in a significant reduction of hyphal extension and haustorium formation and the virulence of Pst on wheat and also, findings indicated that PstMCM1-1 played an important role in sexual reproduction.",X Zhu 2018,2018,1 gene,Zhu-2018-A novel MADS-box transcription factor,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10930,PHI:7870,UniProt,Q83B67,GenBank,AAO91144,,,RSA 493,dotA,,,,,,,777,Coxiella burnetii,,Nine Mile phase II clone 4,Q fever,rodents,10090,Mus musculus (related: house mouse),MH-S cell line,,,alveolar macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29390006,PubMed,10.1371/journal.pone.0192215,PLoS One. 2018 Feb 1;13(2):e0192215,sgilk@iu.edu,"Host gene alteration data available for acyl-CoA transferase-1 (acat-1). T4BSS dotA mutant infected cells had less lipid droplet (LD) accumulation compared to wild type cells demostrating that C. burnetii induces LD accumulation in human and mouse macrophages through a T4BSS-dependent process and blocking LD formation with the pharmacological inhibitors triacsin C or T863, or knocking out acyl-CoA transferase-1 (acat-1) in alveolar macrophages, increased C. burnetii growth at least 2-fold.",M Mulye 2018,2018,1 gene,Mulye-2018-Altering lipid droplet homeostasis,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10931,PHI:7870,UniProt,Q83B67,GenBank,AAO91144,,,RSA 493,dotA,,,,,,,777,Coxiella burnetii,,Nine Mile phase II clone 4,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29390006,PubMed,10.1371/journal.pone.0192215,PLoS One. 2018 Feb 1;13(2):e0192215,sgilk@iu.edu,"Host gene alteration data available for acyl-CoA transferase-1 (acat-1). T4BSS dotA mutant infected cells had less lipid droplet (LD) accumulation compared to wild type cells demostrating that C. burnetii induces LD accumulation in human and mouse macrophages through a T4BSS-dependent process and blocking LD formation with the pharmacological inhibitors triacsin C or T863, or knocking out acyl-CoA transferase-1 (acat-1) in alveolar macrophages, increased C. burnetii growth at least 2-fold.",M Mulye 2018,2018,1 gene,Mulye-2018-Altering lipid droplet homeostasis,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10932,PHI:7871,UniProt,Q5H6J7,GenBank,AAW73423,,,KACC10331,XylR,,,,,,,347,Xanthomonas oryzae,342109,pv. oryzae strain MAFF 311018,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,LacI-type transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29360015,PubMed,10.1094/MPMI-11-17-0277-R,Mol Plant Microbe Interact. 2018 Jan 23,s_tsuge@ kpu.ac.jp,"In the infection process, xylose in rice leaves may have inactivated the negative regulator XylR, and as a result virulence of the mutant was comparable to that of the wild type.",Y Ikawa 2018,2018,1 gene,Ikawa-2018-Concomitant regulation by a LacI-ty,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10933,PHI:7872,UniProt,J4KNK0,GenBank,EJP65839,,,ARSEF 2860,Gcn5 (BBA_05250),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone acetyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2; hydroxyurea; Congo red; menadione; methyl methanesulfonate; camptothecin; NaCl; KCl; sorbitol; calcofluor white,H2O2: CHEBI:16240; hydroxyurea: CHEBI:44423; Congo red: CHEBI:34653; menadione: CHEBI:28869; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,29417710,PubMed,10.1111/1462-2920.14066,Environ Microbiol. 2018 Feb 7,mgfeng@zju.edu.cn,Gcn5 activated asexual development pathway by acetylating H3K14 and regulates the virulence-related cellular events in B. bassiana.,Q Cai 2018,2018,1 gene,Cai-2018-Gcn5-dependent histone H3 acetylation,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10934,PHI:7873,UniProt,G2XE04,GenBank,EGY18052,,,VdLs.17,VdSec22,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,transport protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29419372,PubMed,10.1094/MPMI-12-17-0289-R,Mol Plant Microbe Interact. 2018 Feb 8,kvsubbarao@ucdavis.edu,"Consistent with a role of these enzymes in plant cell wall degradation, pectin, cellulose and xylan utilization were reduced in the VdSec22 or VdSso1 mutant strains, as also a loss of exoproteome cytotoxic activity on cotton leaves.",J Wang 2018,2018,2 genes,Wang-2018-SNARE-Encoding Genes VdSec22 and VdS,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10935,PHI:7874,UniProt,G2WRU5,GenBank,EGY13596,,,VdLs.17,VdSso1,chromosome 2,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,SNARE protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29419372,PubMed,10.1094/MPMI-12-17-0289-R,Mol Plant Microbe Interact. 2018 Feb 8,kvsubbarao@ucdavis.edu,"Consistent with a role of these enzymes in plant cell wall degradation, pectin, cellulose and xylan utilization were reduced in the VdSec22 or VdSso1 mutant strains, as also a loss of exoproteome cytotoxic activity on cotton leaves.",J Wang 2018,2018,2 genes,Wang-2018-SNARE-Encoding Genes VdSec22 and VdS,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10936,PHI:7875,UniProt,Q4WW81,GenBank,EAL91145,,,Af293,FleA,chromosome 5,,,,,,746128,Aspergillus fumigatus,330879,Af293,aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,fucose-specific lectin,,,,increased virulence (hypervirulence),,,,,,,,wild type,aberrant,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29370403,PubMed,10.1093/mmy/myx163,Med Mycol. 2018 Jan 22,ksakai@people.kobe-u.ac.jp,"In the case of the fleA disruptant, the phagocytosed conidia did not contain FleA and induced only a moderate immune response; at the same time, more rapid germination of fleA disruptants facilitated the establishment of infection, since fleA disruption increased fungal pathogenicity.",K Sakai 2018,2018,1 gene,Sakai-2018-Fucose-specific lectin of Aspergill,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10937,PHI:7876,,no data found,,,,,,ndk,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),,,,gingival epithelium,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29359393,PubMed,10.1111/cmi.12825,Cell Microbiol. 2018 Jan 22,yilmaz@musc.edu,"The bacterial control of the host cell death pathways via its effector molecule, Ndk which abrogated epithelial cell death by phosphorylating host cell heat-shock protein 27 (HSP27) on specific serine residues was essential for optimal intracellular life and establishment of P. gingivalis infection in the oral mucosa. gingival epithelial cells (GECs)",J Lee 2018,2018,1 gene,Lee-2018-A novel kinase function of a nucleosi,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10938,PHI:7877,UniProt,A6S8P6,GenBank,ATZ52825,,,B05.10,BcAtg3,BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,ubiquitin-like (UBL) protein-activating enzyme,,,autophagy pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29417220,PubMed,10.1007/s00294-018-0810-3,Curr Genet. 2018 Feb 7,changjun-chen@njau.edu.cn,"The single deletion mutant of BcATG3 and BcATG7 displayed similar biological phenotypes, including the defects in mycelial growth, conidiation and sclerotial formation.",W Ren 2018,2018,2 genes,Ren-2018-Ubiquitin-like activating enzymes BcA,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10939,PHI:7877,UniProt,A6S8P6,GenBank,ATZ52825,,,B05.10,BcAtg3,BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,ubiquitin-like (UBL) protein-activating enzyme,,,autophagy pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29417220,PubMed,10.1007/s00294-018-0810-3,Curr Genet. 2018 Feb 7,changjun-chen@njau.edu.cn,"The single deletion mutant of BcATG3 and BcATG7 displayed similar biological phenotypes, including the defects in mycelial growth, conidiation and sclerotial formation.",W Ren 2018,2018,2 genes,Ren-2018-Ubiquitin-like activating enzymes BcA,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10940,PHI:7877,UniProt,A6S8P6,GenBank,ATZ52825,,,B05.10,BcAtg3,BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,ubiquitin-like (UBL) protein-activating enzyme,,,autophagy pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29417220,PubMed,10.1007/s00294-018-0810-3,Curr Genet. 2018 Feb 7,changjun-chen@njau.edu.cn,"The single deletion mutant of BcATG3 and BcATG7 displayed similar biological phenotypes, including the defects in mycelial growth, conidiation and sclerotial formation.",W Ren 2018,2018,2 genes,Ren-2018-Ubiquitin-like activating enzymes BcA,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10941,PHI:7877,UniProt,A6S8P6,GenBank,ATZ52825,,,B05.10,BcAtg3,BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,ubiquitin-like (UBL) protein-activating enzyme,,,autophagy pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29417220,PubMed,10.1007/s00294-018-0810-3,Curr Genet. 2018 Feb 7,changjun-chen@njau.edu.cn,"The single deletion mutant of BcATG3 and BcATG7 displayed similar biological phenotypes, including the defects in mycelial growth, conidiation and sclerotial formation.",W Ren 2018,2018,2 genes,Ren-2018-Ubiquitin-like activating enzymes BcA,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10942,PHI:7878,UniProt,G2XR75,GenBank,ATZ53677,,,B05.10,BcAtg7,BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,ubiquitin-like (UBL) protein-activating enzyme,,,autophagy pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29417220,PubMed,10.1007/s00294-018-0810-3,Curr Genet. 2018 Feb 7,changjun-chen@njau.edu.cn,"The single deletion mutant of BcATG3 and BcATG7 displayed similar biological phenotypes, including the defects in mycelial growth, conidiation and sclerotial formation.",W Ren 2018,2018,2 genes,Ren-2018-Ubiquitin-like activating enzymes BcA,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10943,PHI:7878,UniProt,G2XR75,GenBank,ATZ53677,,,B05.10,BcAtg7,BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,ubiquitin-like (UBL) protein-activating enzyme,,,autophagy pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29417220,PubMed,10.1007/s00294-018-0810-3,Curr Genet. 2018 Feb 7,changjun-chen@njau.edu.cn,"The single deletion mutant of BcATG3 and BcATG7 displayed similar biological phenotypes, including the defects in mycelial growth, conidiation and sclerotial formation.",W Ren 2018,2018,2 genes,Ren-2018-Ubiquitin-like activating enzymes BcA,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10944,PHI:7878,UniProt,G2XR75,GenBank,ATZ53677,,,B05.10,BcAtg7,BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,ubiquitin-like (UBL) protein-activating enzyme,,,autophagy pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29417220,PubMed,10.1007/s00294-018-0810-3,Curr Genet. 2018 Feb 7,changjun-chen@njau.edu.cn,"The single deletion mutant of BcATG3 and BcATG7 displayed similar biological phenotypes, including the defects in mycelial growth, conidiation and sclerotial formation.",W Ren 2018,2018,2 genes,Ren-2018-Ubiquitin-like activating enzymes BcA,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10945,PHI:7878,UniProt,G2XR75,GenBank,ATZ53677,,,B05.10,BcAtg7,BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,ubiquitin-like (UBL) protein-activating enzyme,,,autophagy pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29417220,PubMed,10.1007/s00294-018-0810-3,Curr Genet. 2018 Feb 7,changjun-chen@njau.edu.cn,"The single deletion mutant of BcATG3 and BcATG7 displayed similar biological phenotypes, including the defects in mycelial growth, conidiation and sclerotial formation.",W Ren 2018,2018,2 genes,Ren-2018-Ubiquitin-like activating enzymes BcA,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10946,PHI:7879,UniProt,J9VFF7,GenBank,AFR93082,,,H99,Cer1 (CNAG_06717),chromosome 2,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/JCrHsd,,,lung; brain,acyl-CoA-dependent ceramide synthase,,,ceramide biosynthesis,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,YVS,29425496,PubMed,10.1016/j.celrep.2018.01.035,Cell Rep. 2018 Feb 6;22(6):1392-1400,maurizio.delpoeta@stonybrook.edu,"Cer1 was critical for the biosynthesis of C18 ceramides, whereas Δcer2 and Δcer3 showed more subtle lipid phenotypes and appear to fine-tune the abundance of less common lipids.",M A Munshi 2018,2018,3 genes,Munshi-2018-The Role of Ceramide Synthases in,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10947,PHI:7880,UniProt,J9VMM2,GenBank,AFR95732,,,H99,Cer2 (CNAG_02086),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/JCrHsd,,,lung; brain,acyl-CoA-dependent ceramide synthase,,,ceramide biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29425496,PubMed,10.1016/j.celrep.2018.01.035,Cell Rep. 2018 Feb 6;22(6):1392-1400,maurizio.delpoeta@stonybrook.edu,"Cer1 was critical for the biosynthesis of C18 ceramides, whereas Δcer2 and Δcer3 showed more subtle lipid phenotypes and appear to fine-tune the abundance of less common lipids.",M A Munshi 2018,2018,3 genes,Munshi-2018-The Role of Ceramide Synthases in,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10948,PHI:7881,UniProt,J9VQN5,GenBank,AFR95731,,,H99,Cer3 (CNAG_02087),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/JCrHsd,,,lung; brain,acyl-CoA-dependent ceramide synthase,,,ceramide biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29425496,PubMed,10.1016/j.celrep.2018.01.035,Cell Rep. 2018 Feb 6;22(6):1392-1400,maurizio.delpoeta@stonybrook.edu,"Cer1 was critical for the biosynthesis of C18 ceramides, whereas Δcer2 and Δcer3 showed more subtle lipid phenotypes and appear to fine-tune the abundance of less common lipids.",M A Munshi 2018,2018,3 genes,Munshi-2018-The Role of Ceramide Synthases in,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10949,PHI:7882,UniProt,Q8XY83,GenBank,CAD15582,,,GMI1000,PrhO (Rsc1880),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,putative LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29363870,PubMed,10.1111/mpp.12660,Mol Plant Pathol. 2018 Jan 24,bioyongzhang@swu.edu.cn,"Deletion of prhO did not alter biofilm formation, swimming mobility and in planta growth.",Y Zhang 2018,2018,1 gene,Zhang-2018-A putative LysR-type transcriptiona,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10950,PHI:7882,UniProt,Q8XY83,GenBank,CAD15582,,,GMI1000,PrhO (Rsc1880),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,putative LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29363870,PubMed,10.1111/mpp.12660,Mol Plant Pathol. 2018 Jan 24,bioyongzhang@swu.edu.cn,"Deletion of prhO did not alter biofilm formation, swimming mobility and in planta growth.",Y Zhang 2018,2018,1 gene,Zhang-2018-A putative LysR-type transcriptiona,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10951,PHI:7882,UniProt,Q8XY83,GenBank,CAD15582,,,GMI1000,PrhO (Rsc1880),,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,putative LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29363870,PubMed,10.1111/mpp.12660,Mol Plant Pathol. 2018 Jan 24,bioyongzhang@swu.edu.cn,"Deletion of prhO did not alter biofilm formation, swimming mobility and in planta growth.",Y Zhang 2018,2018,1 gene,Zhang-2018-A putative LysR-type transcriptiona,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10952,PHI:7882,UniProt,Q8XY83,GenBank,CAD15582,,,GMI1000,PrhO (Rsc1880),,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,putative LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29363870,PubMed,10.1111/mpp.12660,Mol Plant Pathol. 2018 Jan 24,bioyongzhang@swu.edu.cn,"Deletion of prhO did not alter biofilm formation, swimming mobility and in planta growth.",Y Zhang 2018,2018,1 gene,Zhang-2018-A putative LysR-type transcriptiona,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10953,PHI:7883,,no data found,,,,,,PcNmrAL1 (Phyca11_505845),,,,,,,4784,Phytophthora capsici,,LT6535,crown infection; leaf spot; foliar blight,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,candidate transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29419371,PubMed,10.1094/MPMI-07-17-0193-R,Mol Plant Microbe Interact. 2018 Feb 8,E.Huitema@dundee.ac.uk,PcNmrAL1 over-expression induces biotrophy-associated genes whilst repressing those associated with necrotrophy.,J Pham 2018,2018,1 gene,Pham-2018-An NMRA-like protein regulates gene,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10954,PHI:7883,,no data found,,,,,,PcNmrAL1 (Phyca11_505845),,,,,,,4784,Phytophthora capsici,763924,LT1534,crown infection; leaf spot; foliar blight,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,candidate transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29419371,PubMed,10.1094/MPMI-07-17-0193-R,Mol Plant Microbe Interact. 2018 Feb 8,E.Huitema@dundee.ac.uk,PcNmrAL1 over-expression induces biotrophy-associated genes whilst repressing those associated with necrotrophy.,J Pham 2018,2018,1 gene,Pham-2018-An NMRA-like protein regulates gene,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10955,PHI:7884,,no data found,GenBank,ABF-0020368,,,,GcpA,,D418A,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29390166,PubMed,10.1111/mpp.12665,Mol Plant Pathol. 2018 Feb 1,chyang@uwm.edu,"All three virulence factors GcpA, egcpB and ecpC, including Pel production, swimming motility and T3SS were essential for the full virulence of D. dadantii in host plants. B. campestris (Chinese cabbage) as reported in paper is a synonym of B. rapa subsp. Pekinensis",X Yuan 2018,2018,3 genes,Yuan-2018-The diguanylate cyclase GcpA inhibit,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10956,PHI:7885,,no data found,GenBank,ABF-0020123,,,,egcpB,,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29390166,PubMed,10.1111/mpp.12665,Mol Plant Pathol. 2018 Feb 1,chyang@uwm.edu,"All three virulence factors GcpA, egcpB and ecpC, including Pel production, swimming motility and T3SS were essential for the full virulence of D. dadantii in host plants. B. campestris (Chinese cabbage) as reported in paper is a synonym of B. rapa subsp. Pekinensis",X Yuan 2018,2018,3 genes,Yuan-2018-The diguanylate cyclase GcpA inhibit,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10957,PHI:7886,,no data found,GenBank,ABF-0020364,,,,ecpC,,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29390166,PubMed,10.1111/mpp.12665,Mol Plant Pathol. 2018 Feb 1,chyang@uwm.edu,"All three virulence factors GcpA, egcpB and ecpC, including Pel production, swimming motility and T3SS were essential for the full virulence of D. dadantii in host plants. B. campestris (Chinese cabbage) as reported in paper is a synonym of B. rapa subsp. Pekinensis",X Yuan 2018,2018,3 genes,Yuan-2018-The diguanylate cyclase GcpA inhibit,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10958,PHI:7884,,no data found,GenBank,ABF-0020368,,,,GcpA,,D418A,,,,PHI:7885,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,diguanylate cyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29390166,PubMed,10.1111/mpp.12665,Mol Plant Pathol. 2018 Feb 1,chyang@uwm.edu,"All three virulence factors GcpA, egcpB and ecpC, including Pel production, swimming motility and T3SS were essential for the full virulence of D. dadantii in host plants. B. campestris (Chinese cabbage) as reported in paper is a synonym of B. rapa subsp. Pekinensis",X Yuan 2018,2018,3 genes,Yuan-2018-The diguanylate cyclase GcpA inhibit,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10959,PHI:7885,,no data found,GenBank,ABF-0020123,,,,egcpB,,,,,,PHI:7884,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,diguanylate cyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29390166,PubMed,10.1111/mpp.12665,Mol Plant Pathol. 2018 Feb 1,chyang@uwm.edu,"All three virulence factors GcpA, egcpB and ecpC, including Pel production, swimming motility and T3SS were essential for the full virulence of D. dadantii in host plants. B. campestris (Chinese cabbage) as reported in paper is a synonym of B. rapa subsp. Pekinensis",X Yuan 2018,2018,3 genes,Yuan-2018-The diguanylate cyclase GcpA inhibit,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10960,PHI:7884,,no data found,GenBank,ABF-0020368,,,,GcpA,,D418A,,,,PHI:7886,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,diguanylate cyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29390166,PubMed,10.1111/mpp.12665,Mol Plant Pathol. 2018 Feb 1,chyang@uwm.edu,"All three virulence factors GcpA, egcpB and ecpC, including Pel production, swimming motility and T3SS were essential for the full virulence of D. dadantii in host plants. B. campestris (Chinese cabbage) as reported in paper is a synonym of B. rapa subsp. Pekinensis",X Yuan 2018,2018,3 genes,Yuan-2018-The diguanylate cyclase GcpA inhibit,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10961,PHI:7886,,no data found,GenBank,ABF-0020364,,,,ecpC,,,,,,PHI:7884,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,diguanylate cyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29390166,PubMed,10.1111/mpp.12665,Mol Plant Pathol. 2018 Feb 1,chyang@uwm.edu,"All three virulence factors GcpA, egcpB and ecpC, including Pel production, swimming motility and T3SS were essential for the full virulence of D. dadantii in host plants. B. campestris (Chinese cabbage) as reported in paper is a synonym of B. rapa subsp. Pekinensis",X Yuan 2018,2018,3 genes,Yuan-2018-The diguanylate cyclase GcpA inhibit,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10962,PHI:7887,UniProt,B2RM93,GenBank,BAG34488,,,ATCC 33277,rgpA,,,,,,PHI:7888; PHI:7889,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,gingipain production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29409911,PubMed,10.1016/j.ejphar.2018.01.028,Eur J Pharmacol. 2018 Feb 6;824:48-56,,Infection with a gingipain-deficient P. gingivalis mutant led to significant reduction in preterm birth and pregnancy loss.,R Takii 2018,2018,3 genes,Takii-2018-Inhibition of gingipains prevents P,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10963,PHI:7888,UniProt,B2RKU0,GenBank,BAG33985,,,ATCC 33277,rgpB,,,,,,PHI:7887; PHI:7889,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,gingipain production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29409911,PubMed,10.1016/j.ejphar.2018.01.028,Eur J Pharmacol. 2018 Feb 6;824:48-56,,Infection with a gingipain-deficient P. gingivalis mutant led to significant reduction in preterm birth and pregnancy loss.,R Takii 2018,2018,3 genes,Takii-2018-Inhibition of gingipains prevents P,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10964,PHI:7889,UniProt,B2RLK2,GenBank,BAG34247,,,ATCC 33277,kgp,,,,,,PHI:7887; PHI:7888,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,gingipain production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29409911,PubMed,10.1016/j.ejphar.2018.01.028,Eur J Pharmacol. 2018 Feb 6;824:48-56,,Infection with a gingipain-deficient P. gingivalis mutant led to significant reduction in preterm birth and pregnancy loss.,R Takii 2018,2018,3 genes,Takii-2018-Inhibition of gingipains prevents P,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10965,PHI:7890,,no data found,GenBank,CAR32588,,,P125109,SEN1005,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29380670,PubMed,10.1080/21505594.2017.1421829,Virulence. 2018 Jan 30:0,bryan.troxell@gmail.com,"The mutant displayed reduced motility and expression of the flagellin structural gene, fliC.",B Troxell 2018,2018,1 gene,Troxell-2018-A type 6 secretion system (T6SS),BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10966,PHI:7892,UniProt,P14756,GenBank,AE004791_8,,,PAO1,lasB,,lasB::Tn5,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,elastase or pseudolysin which is a secreted type II Zn2+ metalloendopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29415890,PubMed,10.1172/jci.insight.96914,JCI Insight. 2018 Feb 8;3(3). pii: 96914,leejs3@upmc.edu,"Host gene alteration data available for thrombospondin-1 (TSP-1). It was shown that thrombospondin-1 (TSP-1), a matricellular glycoprotein released during inflammation, dose-dependently inhibits PA metalloendoprotease LasB, a virulence factor and dministration of LasB inhibitor, genetic disabling of the PA type II secretion system, or functional deletion of LasB improves host defense and neutrophilic inflammation in mice.",Y Qu 2018,2018,1 gene,Qu-2018-Thrombospondin-1 protects against path,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10967,PHI:7893,UniProt,B4E8H8,GenBank,CAR50845,,,J2315,rqpS (BCAL0535),chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29363827,PubMed,10.1111/mmi.13915,Mol Microbiol. 2018 Jan 24,ydeng@scau.edu.cn,"Mutations in rqpS and rqpR exerted overlapping effects on B. cenocepacia transcriptomes and phenotypes, including motility, biofilm formation and virulence.",C Cui 2018,2018,2 genes,Cui-2018-A novel two-component system modulate,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10968,PHI:7894,UniProt,B4E8H7,GenBank,CAR50844,,,J2315,rqpR (BCAL0534),chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29363827,PubMed,10.1111/mmi.13915,Mol Microbiol. 2018 Jan 24,ydeng@scau.edu.cn,"Mutations in rqpS and rqpR exerted overlapping effects on B. cenocepacia transcriptomes and phenotypes, including motility, biofilm formation and virulence.",C Cui 2018,2018,2 genes,Cui-2018-A novel two-component system modulate,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10969,PHI:7895,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ece1p,chromosome 4,R61A or R93A or R61 + R93A or all KR sites mutated to KA (ALL KA),,,,,5476,Candida albicans,,BWP17+cIP30,oropharyngeal candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,271-amino acid parental preproprotein secereting candidalysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29362237,PubMed,10.1128/mBio.02178-17,MBio. 2018 Jan 23;9(1). pii: e02178-17,Selene.Mogavero@hkijena.de,"C. albicans strains harboring mutations of Arg61 and/or Arg93 did not secrete candidalysin, were unable to induce epithelial damage and in?ammatory responses in vitro, and showed attenuated virulence in vivo in a murine model of oropharyngeal candidiasis.",J P Richardson 2018,2018,1 gene,Richardson-2018-Processing of Candida albicans,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10970,PHI:7895,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ece1p,chromosome 4,all KR sites mutated to KA (ALL KA),,,,,5476,Candida albicans,,BWP17+cIP30,oropharyngeal candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue,271-amino acid parental preproprotein secereting candidalysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29362237,PubMed,10.1128/mBio.02178-17,MBio. 2018 Jan 23;9(1). pii: e02178-17,Selene.Mogavero@hkijena.de,"C. albicans strains harboring mutations of Arg61 and/or Arg93 did not secrete candidalysin, were unable to induce epithelial damage and in?ammatory responses in vitro, and showed attenuated virulence in vivo in a murine model of oropharyngeal candidiasis.",J P Richardson 2018,2018,1 gene,Richardson-2018-Processing of Candida albicans,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10971,PHI:7896,UniProt,C6ZEZ6,GenBank,ACF39937,,,81278ZB15,AvrPiz-t,chromosome 7,,,,,,318829,Magnaporthe oryzae,,RO1-1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,29385213,PubMed,10.1371/journal.ppat.1006878,PLoS Pathog. 2018 Jan 31;14(1):e1006878,ningyuese@caas.cn,"Host gene alteration data available for plasma-membrane-localized K+ channel protein, OsAKT1. AvrPiz-t interacted with the rice plasma-membrane-localized K+ channel protein OsAKT1 and specifically suppressed the OsAKT1 mediated K+ currents.",X Shi 2018,2018,1 gene,Shi-2018-The fungal pathogen Magnaporthe oryza,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10972,PHI:7896,UniProt,C6ZEZ6,GenBank,ACF39937,,,81278ZB15,AvrPiz-t,chromosome 7,,,,,,318829,Magnaporthe oryzae,,RB22,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,29385213,PubMed,10.1371/journal.ppat.1006878,PLoS Pathog. 2018 Jan 31;14(1):e1006878,ningyuese@caas.cn,"Host gene alteration data available for plasma-membrane-localized K+ channel protein, OsAKT1. AvrPiz-t interacted with the rice plasma-membrane-localized K+ channel protein OsAKT1 and specifically suppressed the OsAKT1 mediated K+ currents.",X Shi 2018,2018,1 gene,Shi-2018-The fungal pathogen Magnaporthe oryza,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10973,PHI:7897,UniProt,P13128,GenBank,CAA42639,,,12067,hly,,,,,,,1639,Listeria monocytogenes,,serotype 1/2b strain 2011L-2858,listeriosis,eudicots,3656,Cucumis melo (related: muskmelon),var. cantalupo (cantaloupe),,,rind,hemolysin listeriolysin O,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29389865,PubMed,10.3390/pathogens7010018,Pathogens. 2018 Feb 1;7(1). pii: E18,ctparson@ncsu.edu,"PrfA and to a lesser extent, hly, both contributed to the ability of L. monocytogenes to form biofilms, and both determinants were involved in aggregation of L. monocytogenes, however, neither prfA nor hly were found to be required for adherence, growth or competitive fitness of L. monocytogenes on the cantaloupe rind.",R Price 2018,2018,2 genes,Price-2018-The Listeria monocytogenes Key Viru,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10974,PHI:7898,UniProt,P22262,GenBank,CAA43524,,,LO28,prfA,,,,,,,1639,Listeria monocytogenes,,serotype 1/2b strain 2011L-2858,listeriosis,eudicots,3656,Cucumis melo (related: muskmelon),var. cantalupo (cantaloupe),,,rind,regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29389865,PubMed,10.3390/pathogens7010018,Pathogens. 2018 Feb 1;7(1). pii: E18,ctparson@ncsu.edu,"PrfA and to a lesser extent, hly, both contributed to the ability of L. monocytogenes to form biofilms, and both determinants were involved in aggregation of L. monocytogenes, however, neither prfA nor hly were found to be required for adherence, growth or competitive fitness of L. monocytogenes on the cantaloupe rind.",R Price 2018,2018,2 genes,Price-2018-The Listeria monocytogenes Key Viru,BATCH_079,2018-02-01,MC,,,,,,,,,,,,,
,,Record 10975,PHI:7899,UniProt,G1BJ13,GenBank,AEL04135,,,PXO99,yebN,,49ACAUACU55 deletion,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),,,,leaf,leader RNA that functions as a sensor for mn2+,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29522378,PubMed,10.1094/MPMI-02-18-0043-R,Mol Plant Microbe Interact. 2018 Mar 9,czhe@hainu.edu.cn,The data indicated that Mn2+ was not only required as a microelement for plant growth but also acted as a defense molecule to inhibit pathogen growth.,C Li 2018,2018,1 gene,Li-2018-The YebN Leader RNA Acts as a Mn2+ Sen,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10976,PHI:7900,UniProt,Q667Y0,GenBank,CAH22098,,,IP 32953,iscR,,,,,,,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,HTH-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10977,PHI:7901,UniProt,P10858,GenBank,CAF25356,,,IP 32953,YadA,,,,,,,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,adhesin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10978,PHI:7902,UniProt,P40291,GenBank,AAA73398,,,YPIII(pIB1),yscN,,,,,,,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,probable ATP synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10979,PHI:7903,UniProt,P69987,GenBank,CAF25417,,,IP 32953,yscU,,,,,,,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,putative type III secretion protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10980,PHI:7904,UniProt,I3NI96,GenBank,CAH21672,,,IP 32953,phoP,,,,,,,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,response regulator protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10981,PHI:7905,UniProt,Q66FJ6,GenBank,CAH19580,,,IP 32953,hmuR,,,,,,PHI:7906; PHI:7907; PHI:7908; PHI:7909,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,outer membrane hemin receptor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10982,PHI:7906,UniProt,Q66FJ7,GenBank,CAH19579,,,IP 32953,hmuS,,,,,,PHI:7905; PHI:7907; PHI:7908; PHI:7909,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,possible hemin degradation/transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10983,PHI:7907,UniProt,Q66FJ8,GenBank,CAH19578,,,IP 32953,hmuT,,,,,,PHI:7905; PHI:7906; PHI:7908; PHI:7909,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,"ABC transporter, periplasmic hemin-binding protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10984,PHI:7908,UniProt,Q66FJ9,GenBank,CAH19577,,,IP 32953,hmuU,,,,,,PHI:7905; PHI:7906; PHI:7907; PHI:7909,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,hemin import ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10985,PHI:7909,UniProt,Q66FK0,GenBank,CAH19576,,,IP 32953,hmuV,,,,,,PHI:7905; PHI:7906; PHI:7907; PHI:7908,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,"ABC hemin transporter, permease subunit",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10986,PHI:7906,UniProt,Q66FJ7,GenBank,CAH19579,,,IP 32953,hmuS,,,,,,PHI:7907; PHI:7908; PHI:7909,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,possible hemin degradation/transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10987,PHI:7907,UniProt,Q66FJ8,GenBank,CAH19578,,,IP 32953,hmuT,,,,,,PHI:7906; PHI:7908; PHI:7909,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,"ABC transporter, periplasmic hemin-binding protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10988,PHI:7908,UniProt,Q66FJ9,GenBank,CAH19577,,,IP 32953,hmuU,,,,,,PHI:7906; PHI:7907; PHI:7909,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,hemin import ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10989,PHI:7909,UniProt,Q66FK0,GenBank,CAH19576,,,IP 32953,hmuV,,,,,,PHI:7906; PHI:7907; PHI:7908,633,Yersinia pseudotuberculosis,,IP2666,zoonotic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,"ABC hemin transporter, permease subunit",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29520342,PubMed,10.3389/fcimb.2018.00047,Front Cell Infect Microbiol. 2018 Feb 22;8:47,vastone@ucsc.edu,"Yersinia pseudotuberculosis survival in whole blood did not require the Hmu system, but it did require IscR.",L Schwiesow 2018,2018,10 genes,Schwiesow-2018-Control of hmu Heme Uptake Gene,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10990,PHI:7910,UniProt,G2WT19,GenBank,EGY17260,,,VdLs.17,VdPLP (VDAG_00942),chromosome 1,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,root; leaf,patatin-like phospholipase,,,,reduced virulence,,,yes,,,reduced,,reduced,,no,Congo red; calcoflour white,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,29534051,PubMed,10.3390/genes9030162,Genes (Basel). 2018 Mar 13;9(3). pii: E162,chenghongmei@caas.cn,"Vegetative growth and conidiation of VdPLP deletion mutants (DVdPLP) were significantly reduced compared with wild type and complementary strains, but more microsclerotia was formed.",X Qi 2018,2018,1 gene,"Qi-2018-VdPLP, A Patatin-Like Phospholipase in",BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10991,PHI:7911,UniProt,W2MG57,GenBank,AOV63054,,,98151,ppxyn1,,,,,,,4792,Phytophthora nicotianae,,98151,black shank (tobacco),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,"endo-beta-1,4-xylanase",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29470644,PubMed,10.1007/s00294-018-0814-z,Curr Genet. 2018 Feb 22,rfliou@ntu.edu.tw,Silencing ppxyn1 and ppxyn2 reduced the virulence of P. parasitica toward tobacco (Nicotiana benthamiana) and tomato plants. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',M W Lai 2018,2018,2 genes,Lai-2018-Two genes encoding GH10 xylanases are,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10992,PHI:7912,UniProt,A0A288Q8R8,GenBank,AOV63055,,,98151,ppxyn2,,,,,,,4792,Phytophthora nicotianae,,98151,black shank (tobacco),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,"endo-beta-1,4-xylanase",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29470644,PubMed,10.1007/s00294-018-0814-z,Curr Genet. 2018 Feb 22,rfliou@ntu.edu.tw,Silencing ppxyn1 and ppxyn2 reduced the virulence of P. parasitica toward tobacco (Nicotiana benthamiana) and tomato plants. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',M W Lai 2018,2018,2 genes,Lai-2018-Two genes encoding GH10 xylanases are,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10993,PHI:7911,UniProt,W2MG57,GenBank,AOV63054,,,98151,ppxyn1,,,,,,,4792,Phytophthora nicotianae,,98151,black shank (tobacco),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Summer Sweet,,,leaf,"endo-beta-1,4-xylanase",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29470644,PubMed,10.1007/s00294-018-0814-z,Curr Genet. 2018 Feb 22,rfliou@ntu.edu.tw,Silencing ppxyn1 and ppxyn2 reduced the virulence of P. parasitica toward tobacco (Nicotiana benthamiana) and tomato plants. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',M W Lai 2018,2018,2 genes,Lai-2018-Two genes encoding GH10 xylanases are,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10994,PHI:7912,UniProt,A0A288Q8R8,GenBank,AOV63055,,,98151,ppxyn2,,,,,,,4792,Phytophthora nicotianae,,98151,black shank (tobacco),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Summer Sweet,,,leaf,"endo-beta-1,4-xylanase",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29470644,PubMed,10.1007/s00294-018-0814-z,Curr Genet. 2018 Feb 22,rfliou@ntu.edu.tw,Silencing ppxyn1 and ppxyn2 reduced the virulence of P. parasitica toward tobacco (Nicotiana benthamiana) and tomato plants. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',M W Lai 2018,2018,2 genes,Lai-2018-Two genes encoding GH10 xylanases are,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10995,PHI:7913,UniProt,P43261,GenBank,CAA77642,,,enterohemorrhagic E.coli (EHEC),eae,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,primates,9606,Homo sapiens (related: human),T84 cell line,,,T-84 cell,intimin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29533744,PubMed,10.1099/mic.0.000645,Microbiology. 2018 Mar 13,s.schuller@uea.ac.uk,"No significant differences in bacterial growth, colonization, epithelial permeability, Stx production and translocation were observed in infections with the mutants versus the wild-type strain. colon carcinoma cells",S L Tran 2018,2018,2 genes,Tran-2018-Shiga toxin 2 translocation across i,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10996,PHI:7914,UniProt,O33976,GenBank,AAB71083,,,RDEC-1,espA,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,primates,9606,Homo sapiens (related: human),T84 cell line,,,T-84 cell,T3SS translocation filament,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29533744,PubMed,10.1099/mic.0.000645,Microbiology. 2018 Mar 13,s.schuller@uea.ac.uk,"No significant differences in bacterial growth, colonization, epithelial permeability, Stx production and translocation were observed in infections with the mutants versus the wild-type strain. colon carcinoma cells",S L Tran 2018,2018,2 genes,Tran-2018-Shiga toxin 2 translocation across i,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10997,PHI:7915,UniProt,Q2FZQ3,GenBank,ABD30072,,,NCTC 8325,fabI,,G113C,,,,PHI:7916,1280,Staphylococcus aureus,,F-182,reduced virulence,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,enoyl-ACP reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29497096,PubMed,10.1038/s41598-018-21925-6,Sci Rep. 2018 Mar 1;8(1):3876,andrew.mcbain@manchester.ac.uk,"Virulence, determined using keratinocyte invasion and Galleria mellonella pathogenicity assays was significantly (p < 0.05) attenuated in 3/4 SCVs and in the non-SCV triclosan-adapted bacterium.",A S Bazaid 2018,2018,4 genes,Bazaid-2018-Fatty Acid Supplementation Reverse,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10998,PHI:7916,UniProt,Q99UN8,GenBank,BAB57392,,,Mu50,fabD,,V111D,,,,PHI:7915,1280,Staphylococcus aureus,,F-182,reduced virulence,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,malonyl CoA-acyl carrier protein transacylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29497096,PubMed,10.1038/s41598-018-21925-6,Sci Rep. 2018 Mar 1;8(1):3876,andrew.mcbain@manchester.ac.uk,"Virulence, determined using keratinocyte invasion and Galleria mellonella pathogenicity assays was significantly (p < 0.05) attenuated in 3/4 SCVs and in the non-SCV triclosan-adapted bacterium.",A S Bazaid 2018,2018,4 genes,Bazaid-2018-Fatty Acid Supplementation Reverse,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 10999,PHI:7915,UniProt,Q2FZQ3,GenBank,ABD30072,,,NCTC 8325,fabI,,A95V,,,,PHI:7916; PHI:7917,1280,Staphylococcus aureus,426430,Newman,reduced virulence,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,enoyl-ACP reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29497096,PubMed,10.1038/s41598-018-21925-6,Sci Rep. 2018 Mar 1;8(1):3876,andrew.mcbain@manchester.ac.uk,"Virulence, determined using keratinocyte invasion and Galleria mellonella pathogenicity assays was significantly (p < 0.05) attenuated in 3/4 SCVs and in the non-SCV triclosan-adapted bacterium.",A S Bazaid 2018,2018,4 genes,Bazaid-2018-Fatty Acid Supplementation Reverse,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11000,PHI:7916,UniProt,Q99UN8,GenBank,BAB57392,,,Mu50,fabD,,Q228K,,,,PHI:7915; PHI:7917,1280,Staphylococcus aureus,426430,Newman,reduced virulence,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,malonyl CoA-acyl carrier protein transacylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29497096,PubMed,10.1038/s41598-018-21925-6,Sci Rep. 2018 Mar 1;8(1):3876,andrew.mcbain@manchester.ac.uk,"Virulence, determined using keratinocyte invasion and Galleria mellonella pathogenicity assays was significantly (p < 0.05) attenuated in 3/4 SCVs and in the non-SCV triclosan-adapted bacterium.",A S Bazaid 2018,2018,4 genes,Bazaid-2018-Fatty Acid Supplementation Reverse,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11001,PHI:7917,UniProt,A0A0H3KBS1,GenBank,BAF67098,,,Newman,NWMN_0826,,H107N,,,,PHI:7915; PHI:7916,1280,Staphylococcus aureus,426430,Newman,reduced virulence,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,NADH-dependent flavin oxidoreductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29497096,PubMed,10.1038/s41598-018-21925-6,Sci Rep. 2018 Mar 1;8(1):3876,andrew.mcbain@manchester.ac.uk,"Virulence, determined using keratinocyte invasion and Galleria mellonella pathogenicity assays was significantly (p < 0.05) attenuated in 3/4 SCVs and in the non-SCV triclosan-adapted bacterium.",A S Bazaid 2018,2018,4 genes,Bazaid-2018-Fatty Acid Supplementation Reverse,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11002,PHI:7915,UniProt,Q2FZQ3,GenBank,ABD30072,,,NCTC 8325,fabI,,A95V,,,,,1280,Staphylococcus aureus,,NCTC 13277,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,enoyl-ACP reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29497096,PubMed,10.1038/s41598-018-21925-6,Sci Rep. 2018 Mar 1;8(1):3876,andrew.mcbain@manchester.ac.uk,"Virulence, determined using keratinocyte invasion and Galleria mellonella pathogenicity assays was significantly (p < 0.05) attenuated in 3/4 SCVs and in the non-SCV triclosan-adapted bacterium.",A S Bazaid 2018,2018,4 genes,Bazaid-2018-Fatty Acid Supplementation Reverse,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11003,PHI:7915,UniProt,Q2FZQ3,GenBank,ABD30072,,,NCTC 8325,fabI,,A95V,,,,,1280,Staphylococcus aureus,,SAR17,reduced virulence,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,enoyl-ACP reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29497096,PubMed,10.1038/s41598-018-21925-6,Sci Rep. 2018 Mar 1;8(1):3876,andrew.mcbain@manchester.ac.uk,"Virulence, determined using keratinocyte invasion and Galleria mellonella pathogenicity assays was significantly (p < 0.05) attenuated in 3/4 SCVs and in the non-SCV triclosan-adapted bacterium.",A S Bazaid 2018,2018,4 genes,Bazaid-2018-Fatty Acid Supplementation Reverse,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11004,PHI:7918,UniProt,Q5HDJ9,GenBank,AAG23888,,,COL,tcaA,,G373V,,,,,1280,Staphylococcus aureus,,SAR2831,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,teicoplanin resistance associated membrane,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29497096,PubMed,10.1038/s41598-018-21925-6,Sci Rep. 2018 Mar 1;8(1):3876,andrew.mcbain@manchester.ac.uk,"Virulence, determined using keratinocyte invasion and Galleria mellonella pathogenicity assays was significantly (p < 0.05) attenuated in 3/4 SCVs and in the non-SCV triclosan-adapted bacterium.",A S Bazaid 2018,2018,4 genes,Bazaid-2018-Fatty Acid Supplementation Reverse,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11005,PHI:7919,UniProt,Q8ZNR3,GenBank,AAL20970,,,LT2; SGSC 1412; ATCC 700720,sopA,,,,,,PHI:7920; PHI:7921,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11006,PHI:7920,UniProt,O30916,GenBank,AAL20023,,,LT2; SGSC 1412; ATCC 700720,sopB,,,,,,PHI:7919; PHI:7921,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11007,PHI:7921,UniProt,Q7CQD4,GenBank,AAL20770,,,LT2; SGSC 1412; ATCC 700720,sopE2,,,,,,PHI:7919; PHI:7920,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11008,PHI:7919,UniProt,Q8ZNR3,GenBank,AAL20970,,,LT2; SGSC 1412; ATCC 700720,sopA,,,,,,PHI:7920; PHI:7922,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11009,PHI:7920,UniProt,O30916,GenBank,AAL20023,,,LT2; SGSC 1412; ATCC 700720,sopB,,,,,,PHI:7919; PHI:7922,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11010,PHI:7922,UniProt,P0CL52,GenBank,AAL21762,,,LT2; SGSC 1412; ATCC 700720,sipA,,,,,,PHI:7919; PHI:7920,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11011,PHI:7920,UniProt,O30916,GenBank,AAL20023,,,LT2; SGSC 1412; ATCC 700720,sopB,,,,,,PHI:7921; PHI:7922,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11012,PHI:7921,UniProt,Q7CQD4,GenBank,AAL20770,,,LT2; SGSC 1412; ATCC 700720,sopE2,,,,,,PHI:7920; PHI:7922,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11013,PHI:7922,UniProt,P0CL52,GenBank,AAL21762,,,LT2; SGSC 1412; ATCC 700720,sipA,,,,,,PHI:7920; PHI:7921,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11014,PHI:7919,UniProt,Q8ZNR3,GenBank,AAL20970,,,LT2; SGSC 1412; ATCC 700720,sopA,,,,,,PHI:7921; PHI:7922,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11015,PHI:7921,UniProt,Q7CQD4,GenBank,AAL20770,,,LT2; SGSC 1412; ATCC 700720,sopE2,,,,,,PHI:7919; PHI:7922,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11016,PHI:7922,UniProt,P0CL52,GenBank,AAL21762,,,LT2; SGSC 1412; ATCC 700720,sipA,,,,,,PHI:7919; PHI:7921,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11017,PHI:7921,UniProt,Q7CQD4,GenBank,AAL20770,,,LT2; SGSC 1412; ATCC 700720,sopE2,,,,,,PHI:7922,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11018,PHI:7922,UniProt,P0CL52,GenBank,AAL21762,,,LT2; SGSC 1412; ATCC 700720,sipA,,,,,,PHI:7921,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11019,PHI:7921,UniProt,Q7CQD4,GenBank,AAL20770,,,LT2; SGSC 1412; ATCC 700720,sopE2,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11020,PHI:7922,UniProt,P0CL52,GenBank,AAL21762,,,LT2; SGSC 1412; ATCC 700720,sipA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11021,PHI:7919,UniProt,Q8ZNR3,GenBank,AAL20970,,,LT2; SGSC 1412; ATCC 700720,sopA,,,,,,PHI:7921,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11022,PHI:7921,UniProt,Q7CQD4,GenBank,AAL20770,,,LT2; SGSC 1412; ATCC 700720,sopE2,,,,,,PHI:7919,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11023,PHI:7920,UniProt,O30916,GenBank,AAL20023,,,LT2; SGSC 1412; ATCC 700720,sopB,,,,,,PHI:7921,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11024,PHI:7921,UniProt,Q7CQD4,GenBank,AAL20770,,,LT2; SGSC 1412; ATCC 700720,sopE2,,,,,,PHI:7920,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11025,PHI:7920,UniProt,O30916,GenBank,AAL20023,,,LT2; SGSC 1412; ATCC 700720,sopB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11026,PHI:7923,UniProt,O52623,GenBank,AAC02071,,,SL1344,sopE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29522566,PubMed,10.1371/journal.ppat.1006925,PLoS Pathog. 2018 Mar 9;14(3):e1006925,mhornef@ukaachen.de,"Host gene alteration data available for myeloid differentiation primary response gene 88 (MyD88). Salmonella expressing SopE, SopE2 or SipA but not ΔsopE2sipA Salmonella were able to invade the epithelium indicating that the production of SopE, SopE2 or SipA is necessary and sufficient to facilitate enterocyte invasion in vivo.",K Zhang 2018,2018,5 genes,Zhang-2018-Minimal SPI1-T3SS effector requirem,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11027,PHI:7924,,no data found,,,,,,VeA,,,,,,,27334,Penicillium expansum,,NRRL 35695,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,global transcription factor,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29517851,PubMed,10.1111/mpp.12673,Mol Plant Pathol. 2018 Mar 8,sophie.lorber@inra.fr,"Like the wild-type and the complemented strains, the null mutant PeΔveA strain was still able to sporulate and to colonize apples, but at a lower rate, however, it could not form coremia either in vitro or in vivo thus limiting its dissemination from natural substrates.",C E H Assaf 2018,2018,1 gene,El Hajj Assaf-2018-Impact of veA on the develo,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11028,PHI:7925,UniProt,Q6FJR5,GenBank,CAG62505,,,CBS 138,Cgyps1,chromosome M,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11029,PHI:7926,UniProt,Q6FVJ4,GenBank,CAG58669,,,CBS 138,Cgyps2,chromosome E,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11030,PHI:7927,UniProt,Q6FVI0,GenBank,CAG58683,,,CBS 138,Cgyps3,chromosome E,,,,,PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11031,PHI:7928,UniProt,Q6FVH9,GenBank,CAG58684,,,CBS 138,Cgyps4,chromosome E,,,,,PHI:7927; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11032,PHI:7929,UniProt,Q6FVH8,GenBank,CAG58685,,,CBS 138,Cgyps5,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11033,PHI:7930,UniProt,Q6FVH7,GenBank,CAG58686,,,CBS 138,Cgyps6,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11034,PHI:7932,UniProt,Q6FVH6,GenBank,CAG58687,,,CBS 138,Cgyps8,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11035,PHI:7933,UniProt,Q6FVH5,GenBank,CAG58688,,,CBS 138,Cgyps9,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11036,PHI:7934,UniProt,Q6FVH4,GenBank,CAG58689,,,CBS 138,Cgyps10,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11037,PHI:7935,UniProt,Q6FVH3,GenBank,CAG58690,,,CBS 138,Cgyps11,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11038,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11039,PHI:7925,UniProt,Q6FJR5,GenBank,CAG62505,,,CBS 138,Cgyps1,chromosome M,,,,,PHI:7926,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11040,PHI:7926,UniProt,Q6FVJ4,GenBank,CAG58669,,,CBS 138,Cgyps2,chromosome E,,,,,PHI:7925,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11041,PHI:7925,UniProt,Q6FJR5,GenBank,CAG62505,,,CBS 138,Cgyps1,chromosome M,,,,,PHI:7931,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11042,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,PHI:7925,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11043,PHI:7925,UniProt,Q6FJR5,GenBank,CAG62505,,,CBS 138,Cgyps1,chromosome M,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11044,PHI:7927,UniProt,Q6FVI0,GenBank,CAG58683,,,CBS 138,Cgyps3,chromosome E,,,,,PHI:7925; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11045,PHI:7928,UniProt,Q6FVH9,GenBank,CAG58684,,,CBS 138,Cgyps4,chromosome E,,,,,PHI:7925; PHI:7927; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11046,PHI:7929,UniProt,Q6FVH8,GenBank,CAG58685,,,CBS 138,Cgyps5,chromosome E,,,,,PHI:7925; PHI:7927; PHI:7928; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11047,PHI:7930,UniProt,Q6FVH7,GenBank,CAG58686,,,CBS 138,Cgyps6,chromosome E,,,,,PHI:7925; PHI:7927; PHI:7928; PHI:7929; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11048,PHI:7932,UniProt,Q6FVH6,GenBank,CAG58687,,,CBS 138,Cgyps8,chromosome E,,,,,PHI:7925; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11049,PHI:7933,UniProt,Q6FVH5,GenBank,CAG58688,,,CBS 138,Cgyps9,chromosome E,,,,,PHI:7925; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11050,PHI:7934,UniProt,Q6FVH4,GenBank,CAG58689,,,CBS 138,Cgyps10,chromosome E,,,,,PHI:7925; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11051,PHI:7935,UniProt,Q6FVH3,GenBank,CAG58690,,,CBS 138,Cgyps11,chromosome E,,,,,PHI:7925; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11052,PHI:7925,UniProt,Q6FJR5,GenBank,CAG62505,,,CBS 138,Cgyps1,chromosome M,,,,,PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11053,PHI:7926,UniProt,Q6FVJ4,GenBank,CAG58669,,,CBS 138,Cgyps2,chromosome E,,,,,PHI:7925; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11054,PHI:7927,UniProt,Q6FVI0,GenBank,CAG58683,,,CBS 138,Cgyps3,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11055,PHI:7928,UniProt,Q6FVH9,GenBank,CAG58684,,,CBS 138,Cgyps4,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11056,PHI:7929,UniProt,Q6FVH8,GenBank,CAG58685,,,CBS 138,Cgyps5,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11057,PHI:7930,UniProt,Q6FVH7,GenBank,CAG58686,,,CBS 138,Cgyps6,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11058,PHI:7932,UniProt,Q6FVH6,GenBank,CAG58687,,,CBS 138,Cgyps8,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11059,PHI:7933,UniProt,Q6FVH5,GenBank,CAG58688,,,CBS 138,Cgyps9,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11060,PHI:7934,UniProt,Q6FVH4,GenBank,CAG58689,,,CBS 138,Cgyps10,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11061,PHI:7935,UniProt,Q6FVH3,GenBank,CAG58690,,,CBS 138,Cgyps11,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11062,PHI:7926,UniProt,Q6FVJ4,GenBank,CAG58669,,,CBS 138,Cgyps2,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11063,PHI:7927,UniProt,Q6FVI0,GenBank,CAG58683,,,CBS 138,Cgyps3,chromosome E,,,,,PHI:7926; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11064,PHI:7928,UniProt,Q6FVH9,GenBank,CAG58684,,,CBS 138,Cgyps4,chromosome E,,,,,PHI:7926; PHI:7927; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11065,PHI:7929,UniProt,Q6FVH8,GenBank,CAG58685,,,CBS 138,Cgyps5,chromosome E,,,,,PHI:7926; PHI:7927; PHI:7928; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11066,PHI:7930,UniProt,Q6FVH7,GenBank,CAG58686,,,CBS 138,Cgyps6,chromosome E,,,,,PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11067,PHI:7932,UniProt,Q6FVH6,GenBank,CAG58687,,,CBS 138,Cgyps8,chromosome E,,,,,PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11068,PHI:7933,UniProt,Q6FVH5,GenBank,CAG58688,,,CBS 138,Cgyps9,chromosome E,,,,,PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11069,PHI:7934,UniProt,Q6FVH4,GenBank,CAG58689,,,CBS 138,Cgyps10,chromosome E,,,,,PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11070,PHI:7935,UniProt,Q6FVH3,GenBank,CAG58690,,,CBS 138,Cgyps11,chromosome E,,,,,PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11071,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,PHI:7926,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11072,PHI:7926,UniProt,Q6FVJ4,GenBank,CAG58669,,,CBS 138,Cgyps2,chromosome E,,,,,PHI:7931,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11073,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11074,PHI:7927,UniProt,Q6FVI0,GenBank,CAG58683,,,CBS 138,Cgyps3,chromosome E,,,,,PHI:7931; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11075,PHI:7928,UniProt,Q6FVH9,GenBank,CAG58684,,,CBS 138,Cgyps4,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11076,PHI:7929,UniProt,Q6FVH8,GenBank,CAG58685,,,CBS 138,Cgyps5,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11077,PHI:7930,UniProt,Q6FVH7,GenBank,CAG58686,,,CBS 138,Cgyps6,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11078,PHI:7932,UniProt,Q6FVH6,GenBank,CAG58687,,,CBS 138,Cgyps8,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11079,PHI:7933,UniProt,Q6FVH5,GenBank,CAG58688,,,CBS 138,Cgyps9,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11080,PHI:7934,UniProt,Q6FVH4,GenBank,CAG58689,,,CBS 138,Cgyps10,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11081,PHI:7935,UniProt,Q6FVH3,GenBank,CAG58690,,,CBS 138,Cgyps11,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11082,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11083,PHI:7926,UniProt,Q6FVJ4,GenBank,CAG58669,,,CBS 138,Cgyps2,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11084,PHI:7927,UniProt,Q6FVI0,GenBank,CAG58683,,,CBS 138,Cgyps3,chromosome E,,,,,PHI:7931; PHI:7926; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11085,PHI:7928,UniProt,Q6FVH9,GenBank,CAG58684,,,CBS 138,Cgyps4,chromosome E,,,,,PHI:7931; PHI:7926; PHI:7927; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11086,PHI:7929,UniProt,Q6FVH8,GenBank,CAG58685,,,CBS 138,Cgyps5,chromosome E,,,,,PHI:7931; PHI:7926; PHI:7927; PHI:7928; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11087,PHI:7930,UniProt,Q6FVH7,GenBank,CAG58686,,,CBS 138,Cgyps6,chromosome E,,,,,PHI:7931; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11088,PHI:7932,UniProt,Q6FVH6,GenBank,CAG58687,,,CBS 138,Cgyps8,chromosome E,,,,,PHI:7931; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11089,PHI:7933,UniProt,Q6FVH5,GenBank,CAG58688,,,CBS 138,Cgyps9,chromosome E,,,,,PHI:7931; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11090,PHI:7934,UniProt,Q6FVH4,GenBank,CAG58689,,,CBS 138,Cgyps10,chromosome E,,,,,PHI:7931; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11091,PHI:7935,UniProt,Q6FVH3,GenBank,CAG58690,,,CBS 138,Cgyps11,chromosome E,,,,,PHI:7931; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11092,PHI:7925,UniProt,Q6FJR5,GenBank,CAG62505,,,CBS 138,Cgyps1,chromosome M,,,,,PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11093,PHI:7926,UniProt,Q6FVJ4,GenBank,CAG58669,,,CBS 138,Cgyps2,chromosome E,,,,,PHI:7925; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11094,PHI:7927,UniProt,Q6FVI0,GenBank,CAG58683,,,CBS 138,Cgyps3,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11095,PHI:7928,UniProt,Q6FVH9,GenBank,CAG58684,,,CBS 138,Cgyps4,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11096,PHI:7929,UniProt,Q6FVH8,GenBank,CAG58685,,,CBS 138,Cgyps5,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11097,PHI:7930,UniProt,Q6FVH7,GenBank,CAG58686,,,CBS 138,Cgyps6,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11098,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11099,PHI:7932,UniProt,Q6FVH6,GenBank,CAG58687,,,CBS 138,Cgyps8,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11100,PHI:7933,UniProt,Q6FVH5,GenBank,CAG58688,,,CBS 138,Cgyps9,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11101,PHI:7934,UniProt,Q6FVH4,GenBank,CAG58689,,,CBS 138,Cgyps10,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11102,PHI:7935,UniProt,Q6FVH3,GenBank,CAG58690,,,CBS 138,Cgyps11,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11103,PHI:7925,UniProt,Q6FJR5,GenBank,CAG62505,,,CBS 138,Cgyps1,chromosome M,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11104,PHI:7926,UniProt,Q6FVJ4,GenBank,CAG58669,,,CBS 138,Cgyps2,chromosome E,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11105,PHI:7927,UniProt,Q6FVI0,GenBank,CAG58683,,,CBS 138,Cgyps3,chromosome E,,,,,PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11106,PHI:7928,UniProt,Q6FVH9,GenBank,CAG58684,,,CBS 138,Cgyps4,chromosome E,,,,,PHI:7927; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11107,PHI:7929,UniProt,Q6FVH8,GenBank,CAG58685,,,CBS 138,Cgyps5,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11108,PHI:7930,UniProt,Q6FVH7,GenBank,CAG58686,,,CBS 138,Cgyps6,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11109,PHI:7932,UniProt,Q6FVH6,GenBank,CAG58687,,,CBS 138,Cgyps8,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11110,PHI:7933,UniProt,Q6FVH5,GenBank,CAG58688,,,CBS 138,Cgyps9,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11111,PHI:7934,UniProt,Q6FVH4,GenBank,CAG58689,,,CBS 138,Cgyps10,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11112,PHI:7935,UniProt,Q6FVH3,GenBank,CAG58690,,,CBS 138,Cgyps11,chromosome E,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11113,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11114,PHI:7925,UniProt,Q6FJR5,GenBank,CAG62505,,,CBS 138,Cgyps1,chromosome M,,,,,PHI:7931,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11115,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,PHI:7925,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11116,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,PHI:7926,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11117,PHI:7926,UniProt,Q6FVJ4,GenBank,CAG58669,,,CBS 138,Cgyps2,chromosome E,,,,,PHI:7931,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; brain,cell surface-associated aspartyl protease (yapsins),,,,unaffected pathogenicity,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11118,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11119,PHI:7927,UniProt,Q6FVI0,GenBank,CAG58683,,,CBS 138,Cgyps3,chromosome E,,,,,PHI:7931; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11120,PHI:7928,UniProt,Q6FVH9,GenBank,CAG58684,,,CBS 138,Cgyps4,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11121,PHI:7929,UniProt,Q6FVH8,GenBank,CAG58685,,,CBS 138,Cgyps5,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11122,PHI:7930,UniProt,Q6FVH7,GenBank,CAG58686,,,CBS 138,Cgyps6,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11123,PHI:7932,UniProt,Q6FVH6,GenBank,CAG58687,,,CBS 138,Cgyps8,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11124,PHI:7933,UniProt,Q6FVH5,GenBank,CAG58688,,,CBS 138,Cgyps9,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11125,PHI:7934,UniProt,Q6FVH4,GenBank,CAG58689,,,CBS 138,Cgyps10,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11126,PHI:7935,UniProt,Q6FVH3,GenBank,CAG58690,,,CBS 138,Cgyps11,chromosome E,,,,,PHI:7931; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11127,PHI:7925,UniProt,Q6FJR5,GenBank,CAG62505,,,CBS 138,Cgyps1,chromosome M,,,,,PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11128,PHI:7926,UniProt,Q6FVJ4,GenBank,CAG58669,,,CBS 138,Cgyps2,chromosome E,,,,,PHI:7925; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11129,PHI:7927,UniProt,Q6FVI0,GenBank,CAG58683,,,CBS 138,Cgyps3,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11130,PHI:7928,UniProt,Q6FVH9,GenBank,CAG58684,,,CBS 138,Cgyps4,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11131,PHI:7929,UniProt,Q6FVH8,GenBank,CAG58685,,,CBS 138,Cgyps5,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11132,PHI:7930,UniProt,Q6FVH7,GenBank,CAG58686,,,CBS 138,Cgyps6,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7931; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11133,PHI:7931,UniProt,Q6FY32,GenBank,CAG57763,,,CBS 138,Cgyps7,chromosome A,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7932; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11134,PHI:7932,UniProt,Q6FVH6,GenBank,CAG58687,,,CBS 138,Cgyps8,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7933; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11135,PHI:7933,UniProt,Q6FVH5,GenBank,CAG58688,,,CBS 138,Cgyps9,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7934; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11136,PHI:7934,UniProt,Q6FVH4,GenBank,CAG58689,,,CBS 138,Cgyps10,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7935,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11137,PHI:7935,UniProt,Q6FVH3,GenBank,CAG58690,,,CBS 138,Cgyps11,chromosome E,,,,,PHI:7925; PHI:7926; PHI:7927; PHI:7928; PHI:7929; PHI:7930; PHI:7931; PHI:7932; PHI:7933; PHI:7934,5478,Candida glabrata,,BG2,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,cell surface-associated aspartyl protease (yapsins),,,,reduced virulence,,,,,,,,,,no,MMS (methyl methane sulfonate); sodium nitrite; menadione; calcium chloride; zinc chloride,methyl methanesulfonate: CHEBI:25255; sodium nitrite: CHEBI:78870; menadione: CHEBI:28869; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,29491142,PubMed,10.1074/jbc.M117.813741,J Biol Chem. 2018 Feb 28. pii: jbc.M117.813741,rkaur@cdfd.org.in,"Lack of CgYapsins augmented the inflammatory response of macrophages during infection in an IL-1beta dependent manner, thereby, underscoring the regulatory role of CgYapsins in the host innate immune response.",M Rasheed 2018,2018,11 genes,Rasheed-2018-Aspartyl proteases in Candida gla,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11138,PHI:7936,UniProt,Q9EXF7,GenBank,CAC20634,,,EGD,inlF,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,"internalin, virulence factor",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29487235,PubMed,10.1128/mBio.00160-18,MBio. 2018 Feb 27;9(1). pii: e00160-18,darren_higgins@hms.harvard.edu,Host gene alteration data available for Vimentin. The L. monocytogenes virulence factor InlF was found to bind vimentin and was necessary for optimal bacterial colonization of the brain.,P Ghosh 2018,2018,1 gene,Ghosh-2018-Invasion of the Brain by Listeria m,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11139,PHI:7936,UniProt,Q9EXF7,GenBank,CAC20634,,,EGD,inlF,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,"internalin, virulence factor",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29487235,PubMed,10.1128/mBio.00160-18,MBio. 2018 Feb 27;9(1). pii: e00160-18,darren_higgins@hms.harvard.edu,Host gene alteration data available for Vimentin. The L. monocytogenes virulence factor InlF was found to bind vimentin and was necessary for optimal bacterial colonization of the brain.,P Ghosh 2018,2018,1 gene,Ghosh-2018-Invasion of the Brain by Listeria m,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11140,PHI:7937,,no data found,GenBank,AFT92728,,,FSC200,FTS_0886,,,,,,,263,Francisella tularensis,351581,FSC200,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,DNA-binding protein HU-beta,,,,reduced virulence,,,,,,,,,,no,CuCl2; H2O2,CuCl2: CHEBI:49553; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29473442,PubMed,10.1080/21505594.2018.1441588,Virulence. 2018 Feb 23:1-35,petra.spidlova@unob.cz,"The inability of the FSC200/hupB mutant strain to persist in the conditions of oxidative stress contributed to reduced replication inside murine macrophages and in vivo attenuation, as well.",P Stojkova 2018,2018,1 gene,Stojkova-2018-HU protein is involved in intrac,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11141,PHI:7938,UniProt,Q7MX71,GenBank,AAQ65554,,,W83,PG0343,,,,,,,837,Porphyromonas gingivalis,242619,W83,periodontitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,L-methionine gamma-lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29488863,PubMed,10.1099/mic.0.000640,Microbiology. 2018 Feb 28,aki@po.mdu.ac.jp,"CH3SH produced by PG0343 was essential for abscess formation in mice, and H2S enhances CH3SH-induced abscess formation.",S Nakamura 2018,2018,1 gene,Nakamura-2018-Porphyromonas gingivalis hydroge,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11142,PHI:7939,UniProt,A6S039,GenBank,XP_001555503,,,B05.10,BcYAK1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,member of the dual-specificity tyrosine phosphorylation-regulated protein kinases,,,,reduced virulence,,,,,,reduced,,,,no,H2O2; NaCl; KCl; sorbitol; glycerol; congo red; iprodione; triadimefon,"H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; glycerol: CHEBI:17754; Congo red: CHEBI:34653; iprodione: CHEBI:28909, CAS:36734-19-7; triadimefon: CHEBI:9665",,,,,gene deletion: full; gene complementation,,,YVS,29515556,PubMed,10.3389/fmicb.2018.00281,Front Microbiol. 2018 Feb 21;9:281,wliang1@qau.edu.cn,"The gene deletion mutant ΔBcYak1 exhibited lower pathogenicity, conidiation and sclerotium formation and was also much more sensitive to H2O2 and the ergosterol biosynthesis inhibitor (EBI) triadimefon, however, Lys252 site-directed mutagenesis mutant strain ΔBcYak1-K252Q (mimicking the acetylation of the site) only showed lower sclerotium formation and higher sensitivity to H2O2.",Q Yang 2018,2018,1 gene,Yang-2018-Involvement of BcYak1 in the Regulat,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11143,PHI:7939,UniProt,A6S039,GenBank,XP_001555503,,,B05.10,BcYAK1,,K252Q,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,member of the dual-specificity tyrosine phosphorylation-regulated protein kinases,,,,unaffected pathogenicity,,,,,,reduced,,,,no,H2O2; NaCl; KCl; sorbitol; glycerol; congo red; iprodione; triadimefon,"H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; glycerol: CHEBI:17754; Congo red: CHEBI:34653; iprodione: CHEBI:28909, CAS:36734-19-7; triadimefon: CHEBI:9665",,,,,gene mutation,,,YVS,29515556,PubMed,10.3389/fmicb.2018.00281,Front Microbiol. 2018 Feb 21;9:281,wliang1@qau.edu.cn,"The gene deletion mutant ΔBcYak1 exhibited lower pathogenicity, conidiation and sclerotium formation and was also much more sensitive to H2O2 and the ergosterol biosynthesis inhibitor (EBI) triadimefon, however, Lys252 site-directed mutagenesis mutant strain ΔBcYak1-K252Q (mimicking the acetylation of the site) only showed lower sclerotium formation and higher sensitivity to H2O2.",Q Yang 2018,2018,1 gene,Yang-2018-Involvement of BcYak1 in the Regulat,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11144,PHI:7940,UniProt,A4L7H2,GenBank,ABO38181,,,,hyd1,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Soldier,,,root,hydrophobin,,,,reduced virulence,,,,,,reduced,,aberrant,wild type,no,Congo red; H2O2; NaCl,Congo red: CHEBI:34653; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,YVS,29517481,PubMed,10.1099/mic.0.000644,Microbiology. 2018 Mar 8,mbidochka@brocku.ca,"Δhyd1/Δhyd2 double mutant was less impaired in root association than Δhyd1 or Δhyd2 and loss of hyd genes affected growth rate, conidiation ability and oosporein production.",S Moonjely 2018,2018,2 genes,Moonjely-2018-Hydrophobins contribute to root,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11145,PHI:7941,UniProt,A5A2F8,GenBank,ABP58683,,,,hyd2,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Soldier,,,root,hydrophobin,,,,reduced virulence,,,,,,reduced,,aberrant,wild type,no,Congo red; H2O2; NaCl,Congo red: CHEBI:34653; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,YVS,29517481,PubMed,10.1099/mic.0.000644,Microbiology. 2018 Mar 8,mbidochka@brocku.ca,"Δhyd1/Δhyd2 double mutant was less impaired in root association than Δhyd1 or Δhyd2 and loss of hyd genes affected growth rate, conidiation ability and oosporein production.",S Moonjely 2018,2018,2 genes,Moonjely-2018-Hydrophobins contribute to root,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11146,PHI:7940,UniProt,A4L7H2,GenBank,ABO38181,,,,hyd1,,,,,,PHI:7941,176275,Beauveria bassiana,,ATCC 90517,white muscardine,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Soldier,,,root,hydrophobin,,,,reduced virulence,,,,,,reduced,,aberrant,wild type,no,Congo red; H2O2; NaCl,Congo red: CHEBI:34653; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,YVS,29517481,PubMed,10.1099/mic.0.000644,Microbiology. 2018 Mar 8,mbidochka@brocku.ca,"Δhyd1/Δhyd2 double mutant was less impaired in root association than Δhyd1 or Δhyd2 and loss of hyd genes affected growth rate, conidiation ability and oosporein production.",S Moonjely 2018,2018,2 genes,Moonjely-2018-Hydrophobins contribute to root,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11147,PHI:7941,UniProt,A5A2F8,GenBank,ABP58683,,,,hyd2,,,,,,PHI:7940,176275,Beauveria bassiana,,ATCC 90517,white muscardine,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Soldier,,,root,hydrophobin,,,,reduced virulence,,,,,,reduced,,aberrant,wild type,no,Congo red; H2O2; NaCl,Congo red: CHEBI:34653; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,YVS,29517481,PubMed,10.1099/mic.0.000644,Microbiology. 2018 Mar 8,mbidochka@brocku.ca,"Δhyd1/Δhyd2 double mutant was less impaired in root association than Δhyd1 or Δhyd2 and loss of hyd genes affected growth rate, conidiation ability and oosporein production.",S Moonjely 2018,2018,2 genes,Moonjely-2018-Hydrophobins contribute to root,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11148,PHI:7942,UniProt,Q51548,GenBank,CAA80959,,,PAO1,pvdA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,"L-ornithine N5-oxygenase, siderophore",,,pyoverdine biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29532717,PubMed,10.1080/21505594.2018.1449508,Virulence. 2018 Mar 13:1-41,kirienko@rice.edu,"P. aeruginosa PA14pvdA, a strain deficient in pyoverdine biosynthesis, had no effect on the host iron pool.",D Kang 2018,2018,1 gene,"Kang-2018-Pyoverdine, a siderophore from Pseud",BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11149,PHI:7943,UniProt,P0C7J1,GenBank,AAM39945,,,ATCC 33913,wxcX,,EZ-Tn5 inserted in wxcX gene,,,,,339,Xanthomonas campestris,,pv. campestris strain Xc17,black rot,eudicots,3712,Brassica oleracea (no common name found),,,,leaf,conserved hypothetical protein,,,,reduced virulence,,,,,,reduced,,,,no,copper sulfate; H2O2; sodium dodecyl sulfate,copper sulfate: CHEBI:23414; H2O2: CHEBI:16240; sodium dodecyl sulfate: CHEBI:8984,,,,,gene mutation; gene complementation,,,YVS,29504631,PubMed,10.1002/jobm.201700591,J Basic Microbiol. 2018 Mar 5,ymhsiao@ctust.edu.tw,"Mutation of wxcX resulted in enhanced bacterial attachment, reduced virulence on the host cabbage, and increased sensitivity to sodium dodecyl sulfate.",Y F Li 2018,2018,1 gene,Liu-2018-WxcX is involved in bacterial attachm,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11150,PHI:7944,UniProt,J9VW42,GenBank,AFR98458,,,H99,Uut1 (CNAG_06230),chromosome 12,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; spleen; brain,UDP-GlcA transporter,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,sodium dodecyl sulfate,sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,29382737,PubMed,10.1128/mBio.02319-17,MBio. 2018 Jan 30;9(1). pii: e02319-17,doering@wustl.edu,"Mutant cells with UUT1 deleted lack capsule polysaccharides and are highly sensitive to environmental stress, as a result, the deletion mutant is internalized and cleared by phagocytes more readily than wild-type cells are and is completely avirulent in mice.",L X Li 2018,2018,1 gene,Li-2018-UDP-Glucuronic Acid Transport Is Requi,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11151,PHI:7944,UniProt,J9VW42,GenBank,AFR98458,,,H99,Uut1 (CNAG_06230),chromosome 12,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,UDP-GlcA transporter,,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,sodium dodecyl sulfate,sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,29382737,PubMed,10.1128/mBio.02319-17,MBio. 2018 Jan 30;9(1). pii: e02319-17,doering@wustl.edu,"Mutant cells with UUT1 deleted lack capsule polysaccharides and are highly sensitive to environmental stress, as a result, the deletion mutant is internalized and cleared by phagocytes more readily than wild-type cells are and is completely avirulent in mice.",L X Li 2018,2018,1 gene,Li-2018-UDP-Glucuronic Acid Transport Is Requi,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11152,PHI:7945,UniProt,Q8PC98,GenBank,AAM40151,,,ATCC 33913,pip (proline iminopeptidase),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana SR1,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29517846,PubMed,10.1111/mpp.12677,Mol Plant Pathol. 2018 Mar 8,jiayt@im.ac.cn,"Pip transgenic Arabidopsis plants were more susceptible to Xcc than their wild-type counterparts were, and that PIP enzymatic activity played an important role in repressing host resistance.",J Kan 2018,2018,1 gene,Kan-2018-A dual role for proline iminopeptidas,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11153,PHI:7945,UniProt,Q8PC98,GenBank,AAM40151,,,ATCC 33913,pip (proline iminopeptidase),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana SR1,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29517846,PubMed,10.1111/mpp.12677,Mol Plant Pathol. 2018 Mar 8,jiayt@im.ac.cn,"Pip transgenic Arabidopsis plants were more susceptible to Xcc than their wild-type counterparts were, and that PIP enzymatic activity played an important role in repressing host resistance.",J Kan 2018,2018,1 gene,Kan-2018-A dual role for proline iminopeptidas,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11154,PHI:7945,UniProt,Q8PC98,GenBank,AAM40151,,,ATCC 33913,pip (proline iminopeptidase),,pipS106A,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana SR1,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; functional test in host: transient expression,,,YVS,29517846,PubMed,10.1111/mpp.12677,Mol Plant Pathol. 2018 Mar 8,jiayt@im.ac.cn,"Pip transgenic Arabidopsis plants were more susceptible to Xcc than their wild-type counterparts were, and that PIP enzymatic activity played an important role in repressing host resistance.",J Kan 2018,2018,1 gene,Kan-2018-A dual role for proline iminopeptidas,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11155,PHI:7945,UniProt,Q8PC98,GenBank,AAM40151,,,ATCC 33913,pip (proline iminopeptidase),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29517846,PubMed,10.1111/mpp.12677,Mol Plant Pathol. 2018 Mar 8,jiayt@im.ac.cn,"Pip transgenic Arabidopsis plants were more susceptible to Xcc than their wild-type counterparts were, and that PIP enzymatic activity played an important role in repressing host resistance.",J Kan 2018,2018,1 gene,Kan-2018-A dual role for proline iminopeptidas,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11156,PHI:7945,UniProt,Q8PC98,GenBank,AAM40151,,,ATCC 33913,pip (proline iminopeptidase),,pipS106A,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; functional test in host: transient expression,,,YVS,29517846,PubMed,10.1111/mpp.12677,Mol Plant Pathol. 2018 Mar 8,jiayt@im.ac.cn,"Pip transgenic Arabidopsis plants were more susceptible to Xcc than their wild-type counterparts were, and that PIP enzymatic activity played an important role in repressing host resistance.",J Kan 2018,2018,1 gene,Kan-2018-A dual role for proline iminopeptidas,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11157,PHI:7945,UniProt,Q8PC98,GenBank,AAM40151,,,ATCC 33913,pip (proline iminopeptidase),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,29517846,PubMed,10.1111/mpp.12677,Mol Plant Pathol. 2018 Mar 8,jiayt@im.ac.cn,"Pip transgenic Arabidopsis plants were more susceptible to Xcc than their wild-type counterparts were, and that PIP enzymatic activity played an important role in repressing host resistance.",J Kan 2018,2018,1 gene,Kan-2018-A dual role for proline iminopeptidas,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11158,PHI:7945,UniProt,Q8PC98,GenBank,AAM40151,,,ATCC 33913,pip (proline iminopeptidase),,pipS106A,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: transgenic plants,,,YVS,29517846,PubMed,10.1111/mpp.12677,Mol Plant Pathol. 2018 Mar 8,jiayt@im.ac.cn,"Pip transgenic Arabidopsis plants were more susceptible to Xcc than their wild-type counterparts were, and that PIP enzymatic activity played an important role in repressing host resistance.",J Kan 2018,2018,1 gene,Kan-2018-A dual role for proline iminopeptidas,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11159,PHI:7946,UniProt,W9BFU2,GenBank,ATM55433,,,FDAARGOS_443,lpxL1 (BN49_2155),,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,lipid A late acyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11160,PHI:7947,UniProt,W9B4X1,GenBank,AIT02281,,,PMK1,lpxL2 (BN49_1538),,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,lipid A late acyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11161,PHI:7946,UniProt,W9BFU2,GenBank,ATM55433,,,FDAARGOS_443,lpxL1 (BN49_2155),,,,,,PHI:7947,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,lipid A late acyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11162,PHI:7947,UniProt,W9B4X1,GenBank,AIT02281,,,PMK1,lpxL2 (BN49_1538),,,,,,PHI:7946,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,lipid A late acyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11163,PHI:7948,UniProt,W1I1Q2,GenBank,CDL64297,,,IS39,lpxO,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,fe2+/alpha-ketoglutaratedependent dioxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11164,PHI:7949,UniProt,A6TFA0,GenBank,ABR79234,,,ATCC 700721; MGH 78578,arnB,,,,,,PHI:7950; PHI:7951; PHI:7952; PHI:7953; PHI:7954; PHI:7955,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative aminotransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11165,PHI:7950,UniProt,A6TF99,GenBank,ABR79233,,,ATCC 700721; MGH 78578,arnC,,,,,,PHI:7949; PHI:7951; PHI:7952; PHI:7953; PHI:7954; PHI:7955,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative sugar transferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11166,PHI:7951,UniProt,A6TF98,GenBank,ABR79232,,,ATCC 700721; MGH 78578,arnA,,,,,,PHI:7949; PHI:7950; PHI:7952; PHI:7953; PHI:7954; PHI:7955,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11167,PHI:7952,UniProt,A6TF97,GenBank,ABR79231,,,ATCC 700721; MGH 78578,arnD,,,,,,PHI:7949; PHI:7950; PHI:7951; PHI:7953; PHI:7954; PHI:7955,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11168,PHI:7953,UniProt,A6TF96,GenBank,ABR79230,,,ATCC 700721; MGH 78578,arnT,,,,,,PHI:7949; PHI:7950; PHI:7951; PHI:7952; PHI:7954; PHI:7955,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,4-amino-4-deoxy-L-arabinose transferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11169,PHI:7954,UniProt,A6TF95,GenBank,ABR79229,,,ATCC 700721; MGH 78578,arnE,,,,,,PHI:7949; PHI:7950; PHI:7951; PHI:7952; PHI:7953; PHI:7955,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11170,PHI:7955,UniProt,A6TF94,GenBank,ABR79228,,,ATCC 700721; MGH 78578,arnF,,,,,,PHI:7949; PHI:7950; PHI:7951; PHI:7952; PHI:7953; PHI:7954,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11171,PHI:7956,UniProt,A6T684,GenBank,ABR76105,,,ATCC 700721; MGH 78578,pagP,,,,,,,573,Klebsiella pneumoniae,,52.145,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,acyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28652313,PubMed,10.1128/IAI.00068-17,Infect Immun. 2017 Aug 18;85(9). pii: e00068-17,j.bengoechea@qub.ac.uk,LpxL2-dependent acylation was important for K. pneumoniae survival and virulence in invertebrates.,G Mills 2017,2017,11 genes,Mills-2017-Identification and characterization,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11172,PHI:7957,UniProt,A0A0Q0BGR4,GenBank,KPY88691,,,ICMP16929,HopBB1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,28132837,PubMed,10.1016/j.chom.2017.01.003,Cell Host Microbe. 2017 Feb 8;21(2):156-168,dangl@email.unc.edu,The Pseudomonas syringae type III effector HopBB1 interacted with TCP14 and activated TCP14-repressed JA response genes and promotes bacterial virulence.,L Yang 2017,2017,1 gene,Yang-2017-Pseudomonas syringae Type III Effect,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11173,PHI:7957,UniProt,A0A0Q0BGR4,GenBank,KPY88691,,,ICMP16929,HopBB1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,28132837,PubMed,10.1016/j.chom.2017.01.003,Cell Host Microbe. 2017 Feb 8;21(2):156-168,dangl@email.unc.edu,The Pseudomonas syringae type III effector HopBB1 interacted with TCP14 and activated TCP14-repressed JA response genes and promotes bacterial virulence.,L Yang 2017,2017,1 gene,Yang-2017-Pseudomonas syringae Type III Effect,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11174,PHI:7958,UniProt,S8GJB1,GenBank,EPT28584,,,ME49,Lcat (TGME49_272420),chromosome VIII,,,,,,5811,Toxoplasma gondii,383379,RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,lecithin-cholesterol acyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29507893,PubMed,10.1128/mSphereDirect.00073-18,mSphere. 2018 Feb 28;3(1). pii: e00073-18,vcarruth@umich.edu,"Catalytic activity of LCAT was found to be necessary for its contribution to egress,as complementation of the knock out with a catalytically dead mutant did not restore the phenotype.",A J Schultz 2018,2018,1 gene,Schultz-2018-Toxoplasma gondii LCAT Primarily,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11175,PHI:7958,UniProt,S8GJB1,GenBank,EPT28584,,,ME49,Lcat (TGME49_272420),chromosome VIII,,,,,,5811,Toxoplasma gondii,383379,RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,lecithin-cholesterol acyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29507893,PubMed,10.1128/mSphereDirect.00073-18,mSphere. 2018 Feb 28;3(1). pii: e00073-18,vcarruth@umich.edu,"Catalytic activity of LCAT was found to be necessary for its contribution to egress,as complementation of the knock out with a catalytically dead mutant did not restore the phenotype.",A J Schultz 2018,2018,1 gene,Schultz-2018-Toxoplasma gondii LCAT Primarily,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11176,PHI:7959,UniProt,Q9R304,GenBank,ADI52677,,,SS1681,nga,,,,,,,1314,Streptococcus pyogenes,,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,nicotine adenine dinucleotide glycohydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,28034602,PubMed,10.1016/j.ajpath.2016.11.003,Am J Pathol. 2017 Mar;187(3):605-613,jmmusser@houstonmethodist.org,"Mutants lacking either SPN or SLO are significantly attenuated in the necrotizing myositis, bacteremia, skin and soft tissue infection infection models and in ability to resist killing by human polymorphonuclear leukocytes.",L Zhu 2017,2017,3 genes,Zhu-2017-Contribution of Secreted NADase and S,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11177,PHI:7959,UniProt,Q9R304,GenBank,ADI52677,,,SS1681,nga,,,,,,PHI:7960,1314,Streptococcus pyogenes,,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,nicotine adenine dinucleotide glycohydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,28034602,PubMed,10.1016/j.ajpath.2016.11.003,Am J Pathol. 2017 Mar;187(3):605-613,jmmusser@houstonmethodist.org,"Mutants lacking either SPN or SLO are significantly attenuated in the necrotizing myositis, bacteremia, skin and soft tissue infection infection models and in ability to resist killing by human polymorphonuclear leukocytes.",L Zhu 2017,2017,3 genes,Zhu-2017-Contribution of Secreted NADase and S,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11178,PHI:7960,UniProt,Q2VJ58,GenBank,AAZ38726,,,JRS4,ifs,,,,,,PHI:7959,1314,Streptococcus pyogenes,,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,immunity factor for SPN,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,28034602,PubMed,10.1016/j.ajpath.2016.11.003,Am J Pathol. 2017 Mar;187(3):605-613,jmmusser@houstonmethodist.org,"Mutants lacking either SPN or SLO are significantly attenuated in the necrotizing myositis, bacteremia, skin and soft tissue infection infection models and in ability to resist killing by human polymorphonuclear leukocytes.",L Zhu 2017,2017,3 genes,Zhu-2017-Contribution of Secreted NADase and S,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11179,PHI:7961,UniProt,P0C0I3,GenBank,AAZ50760,,,MGAS5005,slo,,,,,,,1314,Streptococcus pyogenes,,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,streptolysin O,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,28034602,PubMed,10.1016/j.ajpath.2016.11.003,Am J Pathol. 2017 Mar;187(3):605-613,jmmusser@houstonmethodist.org,"Mutants lacking either SPN or SLO are significantly attenuated in the necrotizing myositis, bacteremia, skin and soft tissue infection infection models and in ability to resist killing by human polymorphonuclear leukocytes.",L Zhu 2017,2017,3 genes,Zhu-2017-Contribution of Secreted NADase and S,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11180,PHI:7959,UniProt,Q9R304,GenBank,ADI52677,,,SS1681,nga,,,,,,PHI:7960; PHI:7961,1314,Streptococcus pyogenes,,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,nicotine adenine dinucleotide glycohydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,28034602,PubMed,10.1016/j.ajpath.2016.11.003,Am J Pathol. 2017 Mar;187(3):605-613,jmmusser@houstonmethodist.org,"Mutants lacking either SPN or SLO are significantly attenuated in the necrotizing myositis, bacteremia, skin and soft tissue infection infection models and in ability to resist killing by human polymorphonuclear leukocytes.",L Zhu 2017,2017,3 genes,Zhu-2017-Contribution of Secreted NADase and S,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11181,PHI:7960,UniProt,Q2VJ58,GenBank,AAZ38726,,,JRS4,ifs,,,,,,PHI:7959; PHI:7961,1314,Streptococcus pyogenes,,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,immunity factor for SPN,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,28034602,PubMed,10.1016/j.ajpath.2016.11.003,Am J Pathol. 2017 Mar;187(3):605-613,jmmusser@houstonmethodist.org,"Mutants lacking either SPN or SLO are significantly attenuated in the necrotizing myositis, bacteremia, skin and soft tissue infection infection models and in ability to resist killing by human polymorphonuclear leukocytes.",L Zhu 2017,2017,3 genes,Zhu-2017-Contribution of Secreted NADase and S,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11182,PHI:7961,UniProt,P0C0I3,GenBank,AAZ50760,,,MGAS5005,slo,,,,,,PHI:7959; PHI:7960,1314,Streptococcus pyogenes,,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,streptolysin O,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,28034602,PubMed,10.1016/j.ajpath.2016.11.003,Am J Pathol. 2017 Mar;187(3):605-613,jmmusser@houstonmethodist.org,"Mutants lacking either SPN or SLO are significantly attenuated in the necrotizing myositis, bacteremia, skin and soft tissue infection infection models and in ability to resist killing by human polymorphonuclear leukocytes.",L Zhu 2017,2017,3 genes,Zhu-2017-Contribution of Secreted NADase and S,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11183,PHI:7962,UniProt,P69054,GenBank,AAA23893,,,K-12,sdhC,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,succinate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11184,PHI:7963,UniProt,P0AC44,GenBank,AAA23894,,,K-12,sdhD,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,succinate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11185,PHI:7964,UniProt,P0AC41,GenBank,AAA23895,,,K-12,sdhA,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,succinate dehydrogenase flavoprotein subunit,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11186,PHI:7965,UniProt,P07014,GenBank,AAA23896,,,K-12,sdhB,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,succinate dehydrogenase iron-sulfur subunit,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11187,PHI:7964,UniProt,P0AC41,GenBank,AAA23895,,,K-12,sdhA,,sdhA::Tn5,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,succinate dehydrogenase flavoprotein subunit,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11188,PHI:7962,UniProt,P69054,GenBank,AAA23893,,,K-12,sdhC,,,,,,PHI:7963; PHI:7964; PHI:7965,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,succinate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11189,PHI:7963,UniProt,P0AC44,GenBank,AAA23894,,,K-12,sdhD,,,,,,PHI:7962; PHI:7964; PHI:7965,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,succinate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11190,PHI:7964,UniProt,P0AC41,GenBank,AAA23895,,,K-12,sdhA,,,,,,PHI:7962; PHI:7963; PHI:7965,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,succinate dehydrogenase flavoprotein subunit,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11191,PHI:7965,UniProt,P07014,GenBank,AAA23896,,,K-12,sdhB,,,,,,PHI:7962; PHI:7963; PHI:7964,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,succinate dehydrogenase iron-sulfur subunit,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11192,PHI:7966,UniProt,P0A853,GenBank,AAA24676,,,K-12,tnaA,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,tryptophanase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11193,PHI:7964,UniProt,P0AC41,GenBank,AAA23895,,,K-12,sdhA,,,,,,PHI:7966,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,succinate dehydrogenase flavoprotein subunit,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11194,PHI:7966,UniProt,P0A853,GenBank,AAA24676,,,K-12,tnaA,,,,,,PHI:7964,562,Escherichia coli,155864,EDL933,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,intestine,tryptophanase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29515100,PubMed,10.1038/s41419-018-0423-2,Cell Death Dis. 2018 Mar 7;9(3):381,jc923@mail.ncku.edu.tw,It was observed that the virulence of the wild-type EDL933 and the EDL933:ΔsdhA strains when cultured anaerobically were both significantly attenuated compared to the same strains cultured aerobically supporting the notion that EHEC is more toxic in aerobic metabolism.,C J Kuo 2018,2018,5 genes,Kuo-2018-A multi-omic analysis reveals the rol,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11195,PHI:7967,UniProt,A0A0K0GQ25,GenBank,ACD61037,,,PXO99A,PXO_03177,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,conserved hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,sodium dodecyl sulfate,sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,29392817,PubMed,10.1111/mpp.12664,Mol Plant Pathol. 2018 Feb 2,glqian@njau.edu.cn,Inactivation of PXO_03177 significantly impaired the biofilm formation and tolerance to SDS.,B Wang 2018,2018,6 genes,Wang-2018-Dissecting the virulence-related fun,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11196,PHI:7968,UniProt,A0A0K0GLE8,GenBank,ACD59765,,,PXO99A,PXO_01628,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate,sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full,,,YVS,29392817,PubMed,10.1111/mpp.12664,Mol Plant Pathol. 2018 Feb 2,glqian@njau.edu.cn,Inactivation of PXO_03177 significantly impaired the biofilm formation and tolerance to SDS.,B Wang 2018,2018,6 genes,Wang-2018-Dissecting the virulence-related fun,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11197,PHI:7969,UniProt,A0A0K0GRC4,GenBank,ACD61447,,,PXO99A,PXO_02766,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate,sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full,,,YVS,29392817,PubMed,10.1111/mpp.12664,Mol Plant Pathol. 2018 Feb 2,glqian@njau.edu.cn,Inactivation of PXO_03177 significantly impaired the biofilm formation and tolerance to SDS.,B Wang 2018,2018,6 genes,Wang-2018-Dissecting the virulence-related fun,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11198,PHI:7970,UniProt,A0A0K0GFP9,GenBank,ACD56830,,,PXO99A,PXO_03326,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate,sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full,,,YVS,29392817,PubMed,10.1111/mpp.12664,Mol Plant Pathol. 2018 Feb 2,glqian@njau.edu.cn,Inactivation of PXO_03177 significantly impaired the biofilm formation and tolerance to SDS.,B Wang 2018,2018,6 genes,Wang-2018-Dissecting the virulence-related fun,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11199,PHI:7971,UniProt,A0A0K0GFZ6,GenBank,ACD57027,,,PXO99A,PXO_03847,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate,sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full,,,YVS,29392817,PubMed,10.1111/mpp.12664,Mol Plant Pathol. 2018 Feb 2,glqian@njau.edu.cn,Inactivation of PXO_03177 significantly impaired the biofilm formation and tolerance to SDS.,B Wang 2018,2018,6 genes,Wang-2018-Dissecting the virulence-related fun,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11200,PHI:7972,UniProt,A0A0K0GI94,GenBank,ACD57790,,,PXO99A,PXO_04624,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate,sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full,,,YVS,29392817,PubMed,10.1111/mpp.12664,Mol Plant Pathol. 2018 Feb 2,glqian@njau.edu.cn,Inactivation of PXO_03177 significantly impaired the biofilm formation and tolerance to SDS.,B Wang 2018,2018,6 genes,Wang-2018-Dissecting the virulence-related fun,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11201,PHI:7973,,no data found,GenBank,CDG14660,,,Db11,dsbA1 (SMDB11_4101),,,,,,,615,Serratia marcescens,,Db10,opportunistic infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,periplasmic protein disulfide isomerase I,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346773,PubMed,10.1016/j.celrep.2017.12.075,Cell Rep. 2018 Jan 16;22(3):774-785,s.j.coulthurst@dundee.ac.uk,"Two redundant DsbA proteins were required for virulence and for proper deployment of the T6SS in the opportunistic pathogen Serratia marcescens, with several T6SS components being subject to the action of DsbA in secreting cells.",G Mariano 2018,2018,2 genes,Mariano-2018-Dual Role for DsbA in Attacking a,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11202,PHI:7974,,no data found,GenBank,CDG10831,,,Db11,dsbA2 (SMDB11_0239),,,,,,,615,Serratia marcescens,,Db10,opportunistic infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,thiol:disulfide interchange protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346773,PubMed,10.1016/j.celrep.2017.12.075,Cell Rep. 2018 Jan 16;22(3):774-785,s.j.coulthurst@dundee.ac.uk,"Two redundant DsbA proteins were required for virulence and for proper deployment of the T6SS in the opportunistic pathogen Serratia marcescens, with several T6SS components being subject to the action of DsbA in secreting cells.",G Mariano 2018,2018,2 genes,Mariano-2018-Dual Role for DsbA in Attacking a,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11203,PHI:7973,,no data found,GenBank,CDG14660,,,Db11,dsbA1 (SMDB11_4101),,,,,,PHI:7974,615,Serratia marcescens,,Db10,opportunistic infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,periplasmic protein disulfide isomerase I,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346773,PubMed,10.1016/j.celrep.2017.12.075,Cell Rep. 2018 Jan 16;22(3):774-785,s.j.coulthurst@dundee.ac.uk,"Two redundant DsbA proteins were required for virulence and for proper deployment of the T6SS in the opportunistic pathogen Serratia marcescens, with several T6SS components being subject to the action of DsbA in secreting cells.",G Mariano 2018,2018,2 genes,Mariano-2018-Dual Role for DsbA in Attacking a,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11204,PHI:7974,,no data found,GenBank,CDG10831,,,Db11,dsbA2 (SMDB11_0239),,,,,,PHI:7973,615,Serratia marcescens,,Db10,opportunistic infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,thiol:disulfide interchange protein,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29346773,PubMed,10.1016/j.celrep.2017.12.075,Cell Rep. 2018 Jan 16;22(3):774-785,s.j.coulthurst@dundee.ac.uk,"Two redundant DsbA proteins were required for virulence and for proper deployment of the T6SS in the opportunistic pathogen Serratia marcescens, with several T6SS components being subject to the action of DsbA in secreting cells.",G Mariano 2018,2018,2 genes,Mariano-2018-Dual Role for DsbA in Attacking a,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11205,PHI:7975,UniProt,M7TSY2,GenBank,EMR84269,,,BcDW1,Nop53,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,pre-rRNA processing factor,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,reduced,no,H2O2; NaCl; KCl; sorbitol; glucose; Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; glucose: CHEBI:17234; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,29488307,PubMed,10.1111/1462-2920.14082,Environ Microbiol. 2018 Feb 28,liguihua@jlu.edu.cn,"Loss of BcNOP53 impaired pathogen conidiation and stress adaptation, altered conidial and sclerotial morphology, retarded conidium and sclerotium germination as well as reduced the activities of cell-wall degradation-associated enzymes.",S N Cao 2018,2018,1 gene,Cao-2018-The pre-rRNA processing factor Nop53,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11206,PHI:7975,UniProt,M7TSY2,GenBank,EMR84269,,,BcDW1,Nop53,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf; fruit,pre-rRNA processing factor,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,reduced,no,H2O2; NaCl; KCl; sorbitol; glucose; Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; glucose: CHEBI:17234; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,29488307,PubMed,10.1111/1462-2920.14082,Environ Microbiol. 2018 Feb 28,liguihua@jlu.edu.cn,"Loss of BcNOP53 impaired pathogen conidiation and stress adaptation, altered conidial and sclerotial morphology, retarded conidium and sclerotium germination as well as reduced the activities of cell-wall degradation-associated enzymes.",S N Cao 2018,2018,1 gene,Cao-2018-The pre-rRNA processing factor Nop53,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11207,PHI:7975,UniProt,M7TSY2,GenBank,EMR84269,,,BcDW1,Nop53,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,pre-rRNA processing factor,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,reduced,no,H2O2; NaCl; KCl; sorbitol; glucose; Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; glucose: CHEBI:17234; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,29488307,PubMed,10.1111/1462-2920.14082,Environ Microbiol. 2018 Feb 28,liguihua@jlu.edu.cn,"Loss of BcNOP53 impaired pathogen conidiation and stress adaptation, altered conidial and sclerotial morphology, retarded conidium and sclerotium germination as well as reduced the activities of cell-wall degradation-associated enzymes.",S N Cao 2018,2018,1 gene,Cao-2018-The pre-rRNA processing factor Nop53,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11208,PHI:7975,UniProt,M7TSY2,GenBank,EMR84269,,,BcDW1,Nop53,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,pre-rRNA processing factor,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,reduced,no,H2O2; NaCl; KCl; sorbitol; glucose; Congo red; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; glucose: CHEBI:17234; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,29488307,PubMed,10.1111/1462-2920.14082,Environ Microbiol. 2018 Feb 28,liguihua@jlu.edu.cn,"Loss of BcNOP53 impaired pathogen conidiation and stress adaptation, altered conidial and sclerotial morphology, retarded conidium and sclerotium germination as well as reduced the activities of cell-wall degradation-associated enzymes.",S N Cao 2018,2018,1 gene,Cao-2018-The pre-rRNA processing factor Nop53,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11209,PHI:7976,,no data found,,,,,,rli60,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,riboregulator,,,branched-chain amino acids (BCAA) biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29529043,PubMed,10.1371/journal.pgen.1007283,PLoS Genet. 2018 Mar 12;14(3):e1007283,anathe@post.tau.ac.il,"The double mutant induced virulence gene transcription similarly to WT bacteria, supporting the premise that uncontrolled production of BCAA directly affected CodY regulation, hindering its ability to activate virulence gene expression under low BCAA conditions.",M Brenner 2018,2018,2 genes,Brenner-2018-Controlled branched-chain amino a,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11210,PHI:7977,UniProt,L8DSR3,GenBank,ASW39076,,,FDA00011238,codY,,R61A,,,,PHI:7976,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,global regulator and isoleucine sensor,,,branched-chain amino acids (BCAA) biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29529043,PubMed,10.1371/journal.pgen.1007283,PLoS Genet. 2018 Mar 12;14(3):e1007283,anathe@post.tau.ac.il,"The double mutant induced virulence gene transcription similarly to WT bacteria, supporting the premise that uncontrolled production of BCAA directly affected CodY regulation, hindering its ability to activate virulence gene expression under low BCAA conditions.",M Brenner 2018,2018,2 genes,Brenner-2018-Controlled branched-chain amino a,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11211,PHI:7976,,no data found,,,,,,rli60,,,,,,PHI:7977,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,riboregulator,,,branched-chain amino acids (BCAA) biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29529043,PubMed,10.1371/journal.pgen.1007283,PLoS Genet. 2018 Mar 12;14(3):e1007283,anathe@post.tau.ac.il,"The double mutant induced virulence gene transcription similarly to WT bacteria, supporting the premise that uncontrolled production of BCAA directly affected CodY regulation, hindering its ability to activate virulence gene expression under low BCAA conditions.",M Brenner 2018,2018,2 genes,Brenner-2018-Controlled branched-chain amino a,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11212,PHI:7978,UniProt,I6YHB0,GenBank,CCP46681,,,H37Rv,rv3852,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),Fox Chase SCID,,,lung; spleen,possible histone-like protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28559300,PubMed,10.1128/JB.00129-17,J Bacteriol. 2017 Jul 25;199(16). pii: e00129-17,stewart.cole@epfl.ch,Infection of macrophages as well as severe combined immunodeficient (SCID) mice demonstrated that loss of Rv3852 had no detected influence on the virulence of M. tuberculosis.,N T Odermatt 2017,2017,1 gene,Odermatt-2017-Rv3852 (H-NS) of Mycobacterium t,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11213,PHI:7978,UniProt,I6YHB0,GenBank,CCP46681,,,H37Rv,rv3852,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,possible histone-like protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28559300,PubMed,10.1128/JB.00129-17,J Bacteriol. 2017 Jul 25;199(16). pii: e00129-17,stewart.cole@epfl.ch,Infection of macrophages as well as severe combined immunodeficient (SCID) mice demonstrated that loss of Rv3852 had no detected influence on the virulence of M. tuberculosis.,N T Odermatt 2017,2017,1 gene,Odermatt-2017-Rv3852 (H-NS) of Mycobacterium t,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11214,PHI:7979,UniProt,Q9I5I4,GenBank,AE004509_9,,,PAO1,dspI,,E146A; C127S/C131S; C127S/C131S/C154G,,,,,287,Pseudomonas aeruginosa,652611,PA14,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; kidney,enoyl-coenzyme A (CoA) hydratase,,,pyoverdine production,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29500457,PubMed,10.1038/s41598-018-22300-1,Sci Rep. 2018 Mar 2;8(1):3928,yuluot@scu.edu.cn,"Deletion of dspI results in a remarkable decreased in the pyoverdine production, flagella-dependent swarming motility, and biofilm dispersion as well as attenuated virulence in P. aeruginosa PA14.",L Liu 2018,2018,1 gene,Liu-2018-Structural and functional studies on,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11215,PHI:7979,UniProt,Q9I5I4,GenBank,AE004509_9,,,PAO1,dspI,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; kidney,enoyl-coenzyme A (CoA) hydratase,,,pyoverdine production,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29500457,PubMed,10.1038/s41598-018-22300-1,Sci Rep. 2018 Mar 2;8(1):3928,yuluot@scu.edu.cn,"Deletion of dspI results in a remarkable decreased in the pyoverdine production, flagella-dependent swarming motility, and biofilm dispersion as well as attenuated virulence in P. aeruginosa PA14.",L Liu 2018,2018,1 gene,Liu-2018-Structural and functional studies on,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11216,PHI:7979,UniProt,Q9I5I4,GenBank,AE004509_9,,,PAO1,dspI,,E146A; C127S/C131S; C127S/C131S/C154G,,,,,287,Pseudomonas aeruginosa,652611,PA14,infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,enoyl-coenzyme A (CoA) hydratase,,,pyoverdine production,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29500457,PubMed,10.1038/s41598-018-22300-1,Sci Rep. 2018 Mar 2;8(1):3928,yuluot@scu.edu.cn,"Deletion of dspI results in a remarkable decreased in the pyoverdine production, flagella-dependent swarming motility, and biofilm dispersion as well as attenuated virulence in P. aeruginosa PA14. adenocarcinoma alveolar basal epithelial cells",L Liu 2018,2018,1 gene,Liu-2018-Structural and functional studies on,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11217,PHI:7979,UniProt,Q9I5I4,GenBank,AE004509_9,,,PAO1,dspI,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,enoyl-coenzyme A (CoA) hydratase,,,pyoverdine production,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29500457,PubMed,10.1038/s41598-018-22300-1,Sci Rep. 2018 Mar 2;8(1):3928,yuluot@scu.edu.cn,"Deletion of dspI results in a remarkable decreased in the pyoverdine production, flagella-dependent swarming motility, and biofilm dispersion as well as attenuated virulence in P. aeruginosa PA14. adenocarcinoma alveolar basal epithelial cells",L Liu 2018,2018,1 gene,Liu-2018-Structural and functional studies on,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11218,PHI:7980,UniProt,Q6FXU7,GenBank,CAG57683,,,CBS 138,CgPDR1,chromosome A,G1099D; P927S; L344S; G346D,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,Zn(2)-Cys(6) pleiotropic drug resistance transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29464833,PubMed,10.1111/myc.12756,Mycoses. 2018 Feb 21,pyb9861@sina.com,"GOF mutations in CgPDR1 conferred drug resistance and increased adherence in the clinical strains, possibly endowing C. glabrata with increased viability and pathogenicity.",Q Ni 2018,2018,2 genes,Ni-2018-CgPDR1 gain-of-function mutations lead,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11219,PHI:7980,UniProt,Q6FXU7,GenBank,CAG57683,,,CBS 138,CgPDR1,chromosome A,G1099D; P927S; L344S; G346D,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,primates,9606,Homo sapiens (related: human),HEK293T cell line,,,HEK-293T cell,Zn(2)-Cys(6) pleiotropic drug resistance transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29464833,PubMed,10.1111/myc.12756,Mycoses. 2018 Feb 21,pyb9861@sina.com,"GOF mutations in CgPDR1 conferred drug resistance and increased adherence in the clinical strains, possibly endowing C. glabrata with increased viability and pathogenicity. embryonic kidney epithelial cells",Q Ni 2018,2018,2 genes,Ni-2018-CgPDR1 gain-of-function mutations lead,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11220,PHI:7981,UniProt,Q6FUW5,GenBank,CAG58898,,,CBS 138,EPA1,chromosome E,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,primates,9606,Homo sapiens (related: human),HEK293T cell line,,,HEK-293T cell,adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29464833,PubMed,10.1111/myc.12756,Mycoses. 2018 Feb 21,pyb9861@sina.com,"GOF mutations in CgPDR1 conferred drug resistance and increased adherence in the clinical strains, possibly endowing C. glabrata with increased viability and pathogenicity. embryonic kidney epithelial cells",Q Ni 2018,2018,2 genes,Ni-2018-CgPDR1 gain-of-function mutations lead,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11221,PHI:7982,UniProt,P9WN99,GenBank,CCP42739,,,H37Rv,rodA,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,transglycosylase,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29530985,PubMed,10.1074/jbc.M117.811190,J Biol Chem. 2018 Mar 12. pii: jbc.M117.811190,vinaykn@nii.ac.in,"In a guinea pig infection model, RodA and PbpA were found to be required for both, bacterial survival as well as formation of granuloma structures.",D Arora 2018,2018,2 genes,Arora-2018-The transpeptidase PbpA and non-can,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11222,PHI:7983,UniProt,P9WKD1,GenBank,CCP42738,,,H37Rv,pbpA,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,transpeptidase,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29530985,PubMed,10.1074/jbc.M117.811190,J Biol Chem. 2018 Mar 12. pii: jbc.M117.811190,vinaykn@nii.ac.in,"In a guinea pig infection model, RodA and PbpA were found to be required for both, bacterial survival as well as formation of granuloma structures.",D Arora 2018,2018,2 genes,Arora-2018-The transpeptidase PbpA and non-can,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11223,PHI:7982,UniProt,P9WN99,GenBank,CCP42739,,,H37Rv,rodA,,,,,,PHI:7983,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,transglycosylase,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full,,,YVS,29530985,PubMed,10.1074/jbc.M117.811190,J Biol Chem. 2018 Mar 12. pii: jbc.M117.811190,vinaykn@nii.ac.in,"In a guinea pig infection model, RodA and PbpA were found to be required for both, bacterial survival as well as formation of granuloma structures.",D Arora 2018,2018,2 genes,Arora-2018-The transpeptidase PbpA and non-can,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11224,PHI:7983,UniProt,P9WKD1,GenBank,CCP42738,,,H37Rv,pbpA,,,,,,PHI:7982,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,transpeptidase,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full,,,YVS,29530985,PubMed,10.1074/jbc.M117.811190,J Biol Chem. 2018 Mar 12. pii: jbc.M117.811190,vinaykn@nii.ac.in,"In a guinea pig infection model, RodA and PbpA were found to be required for both, bacterial survival as well as formation of granuloma structures.",D Arora 2018,2018,2 genes,Arora-2018-The transpeptidase PbpA and non-can,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11225,PHI:7982,UniProt,P9WN99,GenBank,CCP42739,,,H37Rv,rodA,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10141,Cavia porcellus (related: domestic guinea pig),Duncan-Hartley,,,lung; spleen,transglycosylase,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29530985,PubMed,10.1074/jbc.M117.811190,J Biol Chem. 2018 Mar 12. pii: jbc.M117.811190,vinaykn@nii.ac.in,"In a guinea pig infection model, RodA and PbpA were found to be required for both, bacterial survival as well as formation of granuloma structures.",D Arora 2018,2018,2 genes,Arora-2018-The transpeptidase PbpA and non-can,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11226,PHI:7983,UniProt,P9WKD1,GenBank,CCP42738,,,H37Rv,pbpA,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10141,Cavia porcellus (related: domestic guinea pig),Duncan-Hartley,,,lung; spleen,transpeptidase,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29530985,PubMed,10.1074/jbc.M117.811190,J Biol Chem. 2018 Mar 12. pii: jbc.M117.811190,vinaykn@nii.ac.in,"In a guinea pig infection model, RodA and PbpA were found to be required for both, bacterial survival as well as formation of granuloma structures.",D Arora 2018,2018,2 genes,Arora-2018-The transpeptidase PbpA and non-can,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11227,PHI:7982,UniProt,P9WN99,GenBank,CCP42739,,,H37Rv,rodA,,,,,,PHI:7983,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10141,Cavia porcellus (related: domestic guinea pig),Duncan-Hartley,,,lung; spleen,transglycosylase,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full,,,YVS,29530985,PubMed,10.1074/jbc.M117.811190,J Biol Chem. 2018 Mar 12. pii: jbc.M117.811190,vinaykn@nii.ac.in,"In a guinea pig infection model, RodA and PbpA were found to be required for both, bacterial survival as well as formation of granuloma structures.",D Arora 2018,2018,2 genes,Arora-2018-The transpeptidase PbpA and non-can,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11228,PHI:7983,UniProt,P9WKD1,GenBank,CCP42738,,,H37Rv,pbpA,,,,,,PHI:7982,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10141,Cavia porcellus (related: domestic guinea pig),Duncan-Hartley,,,lung; spleen,transpeptidase,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full,,,YVS,29530985,PubMed,10.1074/jbc.M117.811190,J Biol Chem. 2018 Mar 12. pii: jbc.M117.811190,vinaykn@nii.ac.in,"In a guinea pig infection model, RodA and PbpA were found to be required for both, bacterial survival as well as formation of granuloma structures.",D Arora 2018,2018,2 genes,Arora-2018-The transpeptidase PbpA and non-can,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11229,PHI:7984,UniProt,Q7DC30,GenBank,AAG54843,,,EDL933,GmrA (Z0639),,,,,,,562,Escherichia coli,83334,serotype O157:H7,hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelium,transcriptional activator,,,flagellar biosynthesis,reduced virulence,,,,,,,,,,no,NaCl; KCl,NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene mutation; gene complementation,,,YVS,29520261,PubMed,10.3389/fmicb.2018.00338,Front Microbiol. 2018 Feb 22;9:338,fenglu63@nankai.edu.cn,"OI-29 was not required for adherence, but deletion of OI-29 reduced motility and flagellar biosynthesis in O157:H7.",B Yang 2018,2018,1 gene,"Yang-2018-Transcriptional Activator GmrA, Enco",BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11230,PHI:7984,UniProt,Q7DC30,GenBank,AAG54843,,,EDL933,GmrA (Z0639),,,,,,,562,Escherichia coli,83334,serotype O157:H7,hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,transcriptional activator,,,flagellar biosynthesis,reduced virulence,,,,,,,,,,no,NaCl; KCl,NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene mutation; gene complementation,,,YVS,29520261,PubMed,10.3389/fmicb.2018.00338,Front Microbiol. 2018 Feb 22;9:338,fenglu63@nankai.edu.cn,"OI-29 was not required for adherence, but deletion of OI-29 reduced motility and flagellar biosynthesis in O157:H7.",B Yang 2018,2018,1 gene,"Yang-2018-Transcriptional Activator GmrA, Enco",BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11231,PHI:7985,UniProt,A0A0K2E3Q5,GenBank,AML47549,,,NSUI060,vraS,,,,,,PHI:7986,1307,Streptococcus suis,,SC19,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; liver; spleen; lung; kidney; brain; blood,sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29471718,PubMed,10.1080/21505594.2018.1428519,Virulence. 2018 Feb 23:0,beiwc@mail.hzau.edu.cn,VraSR contributed to neutrophil resistance and that the decreased survival of ΔvraSR in human blood was due to PMN killing.,P Chang 2018,2018,2 genes,Chang-2018-The VraSR regulatory system contrib,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11232,PHI:7986,UniProt,A0A0Z9GQC2,GenBank,ATZ02919,,,CZ130302,vraR,,,,,,PHI:7985,1307,Streptococcus suis,,SC19,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; liver; spleen; lung; kidney; brain; blood,response regulator,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29471718,PubMed,10.1080/21505594.2018.1428519,Virulence. 2018 Feb 23:0,beiwc@mail.hzau.edu.cn,VraSR contributed to neutrophil resistance and that the decreased survival of ΔvraSR in human blood was due to PMN killing.,P Chang 2018,2018,2 genes,Chang-2018-The VraSR regulatory system contrib,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11233,PHI:7987,UniProt,Q18C34,GenBank,CAJ68380,,,630,pdcA,,pdcA::catP,,,,,1496,Clostridioides difficile,272563,630,pseudomembranous colitis,carnivores,9612,Canis lupus (related: gray wolf),subsp. familiaris MDCK cell line,,,MDCK cell,diguanylate kinase signaling protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28652311,PubMed,10.1128/IAI.00347-17,Infect Immun. 2017 Aug 18;85(9). pii: e00347-17,rita_tamayo@med.unc.edu,PdcA::catP mutation causes a moderate reduction in toxin synthesis and is sufficient to render the pdcA mutant strain less cytopathic and cytotoxic to mammalian cells.,E B Purcell 2017,2017,1 gene,Purcell-2017-A nutrient-regulated cyclic digua,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11234,PHI:7988,UniProt,H9DUR1,GenBank,AFB18185,,,Ls16,VdAve1,,,,,,,27337,Verticillium dahliae,,12008,vascular wilt,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: genetic transformation,,,YVS,29451893,PubMed,10.1371/journal.pone.0191824,PLoS One. 2018 Feb 16;13(2):e0191824,richard.harrison@emr.ac.uk,"Transformation of a virulent non-VdAve1 containing isolate, with VdAve1 was found neither to increase nor decrease virulence when inoculated on a susceptible strawberry cultivar.",R Fan 2018,2018,1 gene,Fan-2018-Vegetative compatibility groups parti,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11235,PHI:7989,,no data found,,,,,,AvrSr50,,,,,,,5297,Puccinia graminis,56615,f. sp. tritici,stem rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29269475,PubMed,10.1126/science.aao4810,Science. 2017 Dec 22;358(6370):1607-1610,robert.park@sydney.edu.au,A spontaneous mutant of Pgt virulent to Sr50 contained a 2.5 mega-base pair loss-of-heterozygosity event.,J Chen 2017,2017,1 gene,Chen-2017-Loss of AvrSr50 by somatic exchange,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11236,PHI:7989,,no data found,,,,,,AvrSr50,,,,,,,5297,Puccinia graminis,56615,f. sp. tritici,stem rust,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29269475,PubMed,10.1126/science.aao4810,Science. 2017 Dec 22;358(6370):1607-1610,robert.park@sydney.edu.au,A spontaneous mutant of Pgt virulent to Sr50 contained a 2.5 mega-base pair loss-of-heterozygosity event.,J Chen 2017,2017,1 gene,Chen-2017-Loss of AvrSr50 by somatic exchange,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11237,PHI:7989,,no data found,,,,,,AvrSr50,,,,,,,5297,Puccinia graminis,56615,f. sp. tritici,stem rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Gabo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29269475,PubMed,10.1126/science.aao4810,Science. 2017 Dec 22;358(6370):1607-1610,robert.park@sydney.edu.au,A spontaneous mutant of Pgt virulent to Sr50 contained a 2.5 mega-base pair loss-of-heterozygosity event.,J Chen 2017,2017,1 gene,Chen-2017-Loss of AvrSr50 by somatic exchange,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11238,PHI:7989,,no data found,,,,,,AvrSr50,,,,,,,5297,Puccinia graminis,56615,f. sp. tritici,stem rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Fielder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29269475,PubMed,10.1126/science.aao4810,Science. 2017 Dec 22;358(6370):1607-1610,robert.park@sydney.edu.au,A spontaneous mutant of Pgt virulent to Sr50 contained a 2.5 mega-base pair loss-of-heterozygosity event.,J Chen 2017,2017,1 gene,Chen-2017-Loss of AvrSr50 by somatic exchange,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11239,PHI:7990,UniProt,A0QHC4,GenBank,ABK69491,,,104,LysX,,,,,,,1764,Mycobacterium avium,439334,subsp. hominissuis strain 104,respiratory disease,primates,9606,Homo sapiens (related: human),,,,macrophage,bifunctional protein with lysyl transferase and lysyl-tRNA synthetase activity,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29471363,PubMed,10.1093/infdis/jiy100,J Infect Dis. 2018 Feb 19,lewina@rki.de,The lysX mutant exhibited an enhanced intracellular growth in human blood-derived monocytes.,G Kirubakar 2018,2018,1 gene,Kirubakar-2018-Proteome Analysis of an M.avium,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11240,PHI:7991,UniProt,G4MKY1,GenBank,EHA57616,,,70-15,PoVps9 (MGG_05379),chromosome 1,,,PoVps21; PoRab11; PoRab1,UniProt: G4N8I6; GenBank: EHA51034; UniProt: G4NCH8; GenBank: EHA48275; UniProt: G4MNT9; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,vacuolar protein sorting-associated protein 9,,,,reduced virulence,,yes,,,,reduced; aberrant,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29468804,PubMed,10.1111/1462-2920.14076,Environ Microbiol. 2018 Feb 22,xhliu@zju.edu.cn,"Deletion of the PoMUK1 gene in the Povps9 mutant background exhibited more severe defects in development, autophagy, and endocytosis compared with the Povps9 mutant, indicating that PoMuk1 has some function in autophagy and in endocytosis.",X M 2018,2018,3 genes,Zhu-2018-VPS9 domain-containing proteins are e,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11241,PHI:7992,UniProt,G4N704,GenBank,EHA50768,,,70-15,PoMuk1 (MGG_06476),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29468804,PubMed,10.1111/1462-2920.14076,Environ Microbiol. 2018 Feb 22,xhliu@zju.edu.cn,"Deletion of the PoMUK1 gene in the Povps9 mutant background exhibited more severe defects in development, autophagy, and endocytosis compared with the Povps9 mutant, indicating that PoMuk1 has some function in autophagy and in endocytosis.",X M 2018,2018,3 genes,Zhu-2018-VPS9 domain-containing proteins are e,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11242,PHI:7993,UniProt,G4MYY5,GenBank,EHA53646,,,70-15,PoVrl1 (MGG_10958),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,29468804,PubMed,10.1111/1462-2920.14076,Environ Microbiol. 2018 Feb 22,xhliu@zju.edu.cn,"Deletion of the PoMUK1 gene in the Povps9 mutant background exhibited more severe defects in development, autophagy, and endocytosis compared with the Povps9 mutant, indicating that PoMuk1 has some function in autophagy and in endocytosis.",X M 2018,2018,3 genes,Zhu-2018-VPS9 domain-containing proteins are e,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11243,PHI:7991,UniProt,G4MKY1,GenBank,EHA57616,,,70-15,PoVps9,chromosome 1,,,PoVps21; PoRab11; PoRab1,UniProt: G4N8I6; GenBank: EHA51034; UniProt: G4NCH8; GenBank: EHA48275; UniProt: G4MNT9; Gen,PHI:7992,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,vacuolar protein sorting-associated protein 9,,,,loss of pathogenicity,,yes,,,,reduced; aberrant,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full,,,YVS,29468804,PubMed,10.1111/1462-2920.14076,Environ Microbiol. 2018 Feb 22,xhliu@zju.edu.cn,"Deletion of the PoMUK1 gene in the Povps9 mutant background exhibited more severe defects in development, autophagy, and endocytosis compared with the Povps9 mutant, indicating that PoMuk1 has some function in autophagy and in endocytosis.",X M 2018,2018,3 genes,Zhu-2018-VPS9 domain-containing proteins are e,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11244,PHI:7992,UniProt,G4N704,GenBank,EHA50768,,,70-15,PoMuk1,chromosome 4,,,,,PHI:7991,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,uncharacterized protein,,,,loss of pathogenicity,,yes,,,,reduced; aberrant,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full,,,YVS,29468804,PubMed,10.1111/1462-2920.14076,Environ Microbiol. 2018 Feb 22,xhliu@zju.edu.cn,"Deletion of the PoMUK1 gene in the Povps9 mutant background exhibited more severe defects in development, autophagy, and endocytosis compared with the Povps9 mutant, indicating that PoMuk1 has some function in autophagy and in endocytosis.",X M 2018,2018,3 genes,Zhu-2018-VPS9 domain-containing proteins are e,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11245,PHI:7992,UniProt,G4N704,GenBank,EHA50768,,,70-15,PoMuk1,chromosome 4,,,,,PHI:7993,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,29468804,PubMed,10.1111/1462-2920.14076,Environ Microbiol. 2018 Feb 22,xhliu@zju.edu.cn,"Deletion of the PoMUK1 gene in the Povps9 mutant background exhibited more severe defects in development, autophagy, and endocytosis compared with the Povps9 mutant, indicating that PoMuk1 has some function in autophagy and in endocytosis.",X M 2018,2018,3 genes,Zhu-2018-VPS9 domain-containing proteins are e,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11246,PHI:7993,UniProt,G4MYY5,GenBank,EHA53646,,,70-15,PoVrl1,chromosome 2,,,,,PHI:7992,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,29468804,PubMed,10.1111/1462-2920.14076,Environ Microbiol. 2018 Feb 22,xhliu@zju.edu.cn,"Deletion of the PoMUK1 gene in the Povps9 mutant background exhibited more severe defects in development, autophagy, and endocytosis compared with the Povps9 mutant, indicating that PoMuk1 has some function in autophagy and in endocytosis.",X M 2018,2018,3 genes,Zhu-2018-VPS9 domain-containing proteins are e,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11247,PHI:7994,UniProt,Q04IN8,GenBank,CAA36714,,,"NCTC 7466, serotype II",ply (pneumolysin),,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,macrophage,"pore forming cytolysin, virulence factor",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28630064,PubMed,10.1128/IAI.00201-17,Infect Immun. 2017 Aug 18;85(9). pii: e00201-17,ktsuchiya@staff.kanazawa-u.ac.jp,Host gene alteration data available for caspase-1 and ASC (apoptosis-associated speck-like protein containing a CARD [caspase activation and recruitment domain]). PLY was dispensable for IL-1alpha transcription and pro-IL-1alpha synthesis but was important for the maturation and secretion of IL-1alpha in S. pneumoniae-infected macrophages.,R Fang 2017,2017,1 gene,Fang-2017-Pneumolysin-dependent calpain activa,BATCH_080,2018-03-01,MC,,,,,,,,,,,,,
,,Record 11248,PHI:7995,UniProt,B8N690,GenBank,EED54602,,,NRRL3357,GpaB,,,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::AfpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,G protein alpha subunit,,,,reduced virulence,,,,,,reduced,,increased; aberrant,,no,calcofluor white; Congo red; H2O2,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29534423,PubMed,10.3390/toxins10030117,Toxins (Basel). 2018 Mar 10;10(3). pii: E117,ykl_long@yeah.net,Alfatoxin (AF) biosynthesis and infection on crop seeds were severely impaired in the gpaB-deficient mutant.,Y Liu 2018,2018,1 gene,Liu-2018-G Protein alpha Subunit GpaB is Requi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11249,PHI:7996,UniProt,A0A0H3B1G5,GenBank,ACA67611,,,YPIII,invD,,,,,,,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; colon,invasin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29535184,PubMed,10.1074/jbc.RA117.001068,J Biol Chem.2018 Mar 13. pii: jbc.RA117.001068,andrea.scrima@helmholtz-hzi.de,InvD was potentially involved in the infection process such as in efficient colonization of the host intestinal tract and/or in host immune evasion.,P Sadana 2018,2018,1 gene,Sadana-2018-The invasin D protein from Yersini,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11250,PHI:7997,UniProt,Q2FVT1,GenBank,SAOUHSC_02611,,,,SpdC,,,,WalK; SaeS,UniProt: Q2G2U4; GenBank: ABD29210; UniProt: Q2G2U1; GenBank: ABD29847,,1280,Staphylococcus aureus,,HG001,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Rj:SWISS,,,kidney,Abi-domain containing membrane anchored protein involved in signal sensing and/or transduction,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29543889,PubMed,10.1371/journal.ppat.1006917,PLoS Pathog.2018 Mar 15;14(3):e1006917,sdubrac@pasteur.fr,SpdC was required for S. aureus biofilm formation and virulence in a murine septicemia model.,O Poupel 2018,2018,1 gene,"Poupel-2018-SpdC, a novel virulence factor, co",BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11251,PHI:7998,UniProt,Q83E43,GenBank,AAO90037,,,RSA 493,pldA (CBU_0489),,,,,,,777,Coxiella burnetii,,Nine Mile phase II clone 4,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,outer membrane phospholipase A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29661138,PubMed,10.1186/s12866-018-1181-0,BMC Microbiol. 2018 Apr 16;18(1):33,rheinzen@niaid.nih.gov,PldA was responsible for membrane remodeling of the small cell variants (SCV) developmental form.,C M Stead 2018,2018,1 gene,Stead-2018-A Coxiella burnetii phospholipase A,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11252,PHI:7999,UniProt,Q9I5F6,GenBank,AE004513_3,,,PAO1,putA,,,,,,,287,Pseudomonas aeruginosa,1009714,PAK,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,bifunctional enzyme which converts proline to glutamate,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29632523,PubMed,10.3389/fmicb.2018.00548,Front Microbiol.2018 Mar 26;9:548,zhihuicheng@nankai.edu.cn,Overexpression of a putA gene rescued the ΔpruR mutant strain from the increased sensitivity to H2O2 mediated killing.,R Zheng 2018,2018,1 gene,Zheng-2018-PutA Is Required for Virulence and,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11253,PHI:8000,UniProt,A0A177DU44,GenBank,OAG22770,,,SRC1lrK2f,csn5,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,COP9 signalosome (CSN) protein complex involved in the ubiquitin-proteasome system,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; CaCl2; H2O2; menadione,NaCl: CHEBI:26710; CaCl2: CHEBI:3312; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,29616013,PubMed,10.3389/fmicb.2018.00508,Front Microbiol.2018 Mar 20;9:508,hyli@zju.edu.cn,The growth of ΔAacsn5 mutant was not affected in response to oxidative and osmotic stresses.,M Wang 2018,2018,1 gene,Wang-2018-Csn5 Is Required for the Conidiogene,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11254,PHI:8001,UniProt,M3AVQ5,GenBank,EME81557,,,CIRAD86,Fus3,,,,,,,1873960,Pseudocercospora fijiensis,,,black sigatoka,monocots,4641,Musa acuminata (related: dwarf banana),Nakitembe clone set,,,leaf,mitogen-activated protein kinase,,,MAPK signaling pathway,reduced virulence,,,,yes,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29593757,PubMed,10.3389/fpls.2018.00291,Front Plant Sci. 2018 Mar 13;9:291,L.Tripathi@cgiar.org,"The PfSlt2 and PfFus3 silenced P. fijiensis transformants showed significantly lower gene expression and reduced virulence, invasive growth and lower biomass in infected leaf tissues of East African Highland Banana (EAHB).",F Onyilo 2018,2018,2 genes,Onyilo-2018-Silencing of the Mitogen-Activated,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11255,PHI:8002,UniProt,M3AFB7,GenBank,EME83271,,,CIRAD86,Slt2,,,,,,,1873960,Pseudocercospora fijiensis,,,black sigatoka,monocots,4641,Musa acuminata (related: dwarf banana),Nakitembe clone set,,,leaf,mitogen-activated protein kinase,,,MAPK signaling pathway,reduced virulence,,,,yes,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29593757,PubMed,10.3389/fpls.2018.00291,Front Plant Sci. 2018 Mar 13;9:291,L.Tripathi@cgiar.org,"The PfSlt2 and PfFus3 silenced P. fijiensis transformants showed significantly lower gene expression and reduced virulence, invasive growth and lower biomass in infected leaf tissues of East African Highland Banana (EAHB).",F Onyilo 2018,2018,2 genes,Onyilo-2018-Silencing of the Mitogen-Activated,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11256,PHI:8003,UniProt,D5AGD5,GenBank,ADE30900,,,GZ1,divIVA,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,macrophage,cell division initiation protein,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,29616196,PubMed,10.3389/fcimb.2018.00085,Front Cell Infect Microbiol.2018 Mar 20;8:85,panxiuzhen_2004@163.com,The inactivation of DivIVA led to severe defects in cell division and strongly attenuates pathogenicity.,H Ni 2018,2018,1 gene,Ni-2018-Streptococcus suis DivIVA Protein Is a,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11257,PHI:8004,UniProt,P23484,GenBank,AAA23766,,,K-12,fecI,,,,,,PHI:8005; PHI:8006; PHI:8007; PHI:8008; PHI:8009; PHI:8010,562,Escherichia coli,1167694,serotype O32:H37 strain P4,bovine mastitis,even-toed ungulates,9913,Bos taurus (related: cattle),Holstein Friesian,,,mammary gland,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29615502,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,shlomo.blum@mail.huji.ac.il,"Deletion of fec reduced the rate of growth in milk of MPEC strain P4, whereas fec-transformed non-mammary gland-pathogenic DFEC strain K71 gained the phenotype of the level of growth in milk observed in MPEC. Udder tissue",S E Blum 2018,2018,7 genes,Blum-2018-Postgenomics Characterization of an,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11258,PHI:8005,UniProt,P23485,GenBank,AAA23767,,,K-12,fecR,,,,,,PHI:8004; PHI:8006; PHI:8007; PHI:8008; PHI:8009; PHI:8010,562,Escherichia coli,1167694,serotype O32:H37 strain P4,bovine mastitis,even-toed ungulates,9913,Bos taurus (related: cattle),Holstein Friesian,,,mammary gland,Fec operon regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29615502,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,shlomo.blum@mail.huji.ac.il,"Deletion of fec reduced the rate of growth in milk of MPEC strain P4, whereas fec-transformed non-mammary gland-pathogenic DFEC strain K71 gained the phenotype of the level of growth in milk observed in MPEC. Udder tissue",S E Blum 2018,2018,7 genes,Blum-2018-Postgenomics Characterization of an,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11259,PHI:8006,UniProt,P13036,GenBank,BAE78282,,,K-12,fecA,,,,,,PHI:8004; PHI:8005; PHI:8007; PHI:8008; PHI:8009; PHI:8010,562,Escherichia coli,1167694,serotype O32:H37 strain P4,bovine mastitis,even-toed ungulates,9913,Bos taurus (related: cattle),Holstein Friesian,,,mammary gland,ferric citrate outer membrane transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29615502,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,shlomo.blum@mail.huji.ac.il,"Deletion of fec reduced the rate of growth in milk of MPEC strain P4, whereas fec-transformed non-mammary gland-pathogenic DFEC strain K71 gained the phenotype of the level of growth in milk observed in MPEC. Udder tissue",S E Blum 2018,2018,7 genes,Blum-2018-Postgenomics Characterization of an,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11260,PHI:8007,UniProt,P15028,GenBank,AAA23762,,,K-12,fecB,,,,,,PHI:8004; PHI:8005; PHI:8006; PHI:8008; PHI:8009; PHI:8010,562,Escherichia coli,1167694,serotype O32:H37 strain P4,bovine mastitis,even-toed ungulates,9913,Bos taurus (related: cattle),Holstein Friesian,,,mammary gland,Fe(3+) dicitrate-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29615502,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,shlomo.blum@mail.huji.ac.il,"Deletion of fec reduced the rate of growth in milk of MPEC strain P4, whereas fec-transformed non-mammary gland-pathogenic DFEC strain K71 gained the phenotype of the level of growth in milk observed in MPEC. Udder tissue",S E Blum 2018,2018,7 genes,Blum-2018-Postgenomics Characterization of an,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11261,PHI:8008,UniProt,P15030,GenBank,AAA23763,,,K-12,fecC,,,,,,PHI:8004; PHI:8005; PHI:8006; PHI:8007; PHI:8009; PHI:8010,562,Escherichia coli,1167694,serotype O32:H37 strain P4,bovine mastitis,even-toed ungulates,9913,Bos taurus (related: cattle),Holstein Friesian,,,mammary gland,Fe(3+) dicitrate transport system permease protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29615502,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,shlomo.blum@mail.huji.ac.il,"Deletion of fec reduced the rate of growth in milk of MPEC strain P4, whereas fec-transformed non-mammary gland-pathogenic DFEC strain K71 gained the phenotype of the level of growth in milk observed in MPEC. Udder tissue",S E Blum 2018,2018,7 genes,Blum-2018-Postgenomics Characterization of an,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11262,PHI:8009,UniProt,P15029,GenBank,AAA23764,,,K-12,fecD,,,,,,PHI:8004; PHI:8005; PHI:8006; PHI:8007; PHI:8008; PHI:8010,562,Escherichia coli,1167694,serotype O32:H37 strain P4,bovine mastitis,even-toed ungulates,9913,Bos taurus (related: cattle),Holstein Friesian,,,mammary gland,Fe(3+) dicitrate transport system permease protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29615502,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,shlomo.blum@mail.huji.ac.il,"Deletion of fec reduced the rate of growth in milk of MPEC strain P4, whereas fec-transformed non-mammary gland-pathogenic DFEC strain K71 gained the phenotype of the level of growth in milk observed in MPEC. Udder tissue",S E Blum 2018,2018,7 genes,Blum-2018-Postgenomics Characterization of an,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11263,PHI:8010,UniProt,P15031,GenBank,AAA23765,,,K-12,fecE,,,,,,PHI:8004; PHI:8005; PHI:8006; PHI:8007; PHI:8008; PHI:8009,562,Escherichia coli,1167694,serotype O32:H37 strain P4,bovine mastitis,even-toed ungulates,9913,Bos taurus (related: cattle),Holstein Friesian,,,mammary gland,Fe(3+) dicitrate transport ATP-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29615502,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,shlomo.blum@mail.huji.ac.il,"Deletion of fec reduced the rate of growth in milk of MPEC strain P4, whereas fec-transformed non-mammary gland-pathogenic DFEC strain K71 gained the phenotype of the level of growth in milk observed in MPEC. Udder tissue",S E Blum 2018,2018,7 genes,Blum-2018-Postgenomics Characterization of an,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11264,PHI:8011,UniProt,B9XXL6,GenBank,EEC25260,,,B128,rhpa,,,,,,,210,Helicobacter pylori,1386083,X47-2AL,gastric infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,stomach,DEAD-box RNA helicase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29588407,PubMed,10.1128/mBio.02071-17,MBio.2018 Mar 27;9(2). pii: e02071-17,hdereuse@pasteur.fr,"RhpA was dispensable for growth at 37°C but crucial at 33°C, suggesting an essential role of the helicase in cold adaptation and ΔrhpA mutant was impaired in motility.",L El Mortaji 2018,2018,1 gene,El Mortaji-2018-The Sole DEAD-Box RNA Helicase,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11265,PHI:8012,UniProt,J9VU19,GenBank,AFR97768,,,H99,hda1 (CNAG_01563),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone deacetylase,,,,reduced virulence,yes,,,,,,,,,no,SDS; calcofluor white; Congo red,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29581526,PubMed,10.1038/s41598-018-21965-y,Sci Rep.2018 Mar 26;8(1):5209,andrew.alspaugh@duke.edu,"Although most of the mutants showed some degree of reduced survival in macrophages, the Δhda1 mutant was the most attenuated, and the Δclr61 mutant demonstrated better survival compared to wild-type in this in vitro model of host-pathogen interaction.",F Brandão 2018,2018,7 genes,Brandao-2018-HDAC genes play distinct and redu,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11266,PHI:8013,UniProt,J9W439,GenBank,AFR98990,,,H99,hos2 (CNAG_05563),chromosome 14,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone deacetylase,,,,reduced virulence,,,,,,,,,,no,SDS; calcofluor white; Congo red,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29581526,PubMed,10.1038/s41598-018-21965-y,Sci Rep.2018 Mar 26;8(1):5209,andrew.alspaugh@duke.edu,"Although most of the mutants showed some degree of reduced survival in macrophages, the Δhda1 mutant was the most attenuated, and the Δclr61 mutant demonstrated better survival compared to wild-type in this in vitro model of host-pathogen interaction.",F Brandão 2018,2018,7 genes,Brandao-2018-HDAC genes play distinct and redu,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11267,PHI:8014,UniProt,J9VP39,GenBank,AFR96008,,,H99,rpd3 (CNAG_05690),chromosome 7,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone deacetylase,,,,reduced virulence,,,,,,,,,,no,SDS; calcofluor white; Congo red,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29581526,PubMed,10.1038/s41598-018-21965-y,Sci Rep.2018 Mar 26;8(1):5209,andrew.alspaugh@duke.edu,"Although most of the mutants showed some degree of reduced survival in macrophages, the Δhda1 mutant was the most attenuated, and the Δclr61 mutant demonstrated better survival compared to wild-type in this in vitro model of host-pathogen interaction.",F Brandão 2018,2018,7 genes,Brandao-2018-HDAC genes play distinct and redu,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11268,PHI:8015,UniProt,J9VS57,GenBank,AFR94535,,,H99,clr62 (CNAG_05276),chromosome 4,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone deacetylase,,,,reduced virulence,,,,,,,,,,no,SDS; calcofluor white; Congo red,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29581526,PubMed,10.1038/s41598-018-21965-y,Sci Rep.2018 Mar 26;8(1):5209,andrew.alspaugh@duke.edu,"Although most of the mutants showed some degree of reduced survival in macrophages, the Δhda1 mutant was the most attenuated, and the Δclr61 mutant demonstrated better survival compared to wild-type in this in vitro model of host-pathogen interaction.",F Brandão 2018,2018,7 genes,Brandao-2018-HDAC genes play distinct and redu,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11269,PHI:8016,UniProt,J9VLP0,GenBank,AFR94361,,,H99,hos1 (CNAG_05096),chromosome 4,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; calcofluor white; Congo red,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29581526,PubMed,10.1038/s41598-018-21965-y,Sci Rep.2018 Mar 26;8(1):5209,andrew.alspaugh@duke.edu,"Although most of the mutants showed some degree of reduced survival in macrophages, the Δhda1 mutant was the most attenuated, and the Δclr61 mutant demonstrated better survival compared to wild-type in this in vitro model of host-pathogen interaction.",F Brandão 2018,2018,7 genes,Brandao-2018-HDAC genes play distinct and redu,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11270,PHI:8017,UniProt,J9VJJ7,GenBank,AFR92789,,,H99,hos3 (CNAG_00660),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; calcofluor white; Congo red,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29581526,PubMed,10.1038/s41598-018-21965-y,Sci Rep.2018 Mar 26;8(1):5209,andrew.alspaugh@duke.edu,"Although most of the mutants showed some degree of reduced survival in macrophages, the Δhda1 mutant was the most attenuated, and the Δclr61 mutant demonstrated better survival compared to wild-type in this in vitro model of host-pathogen interaction.",F Brandão 2018,2018,7 genes,Brandao-2018-HDAC genes play distinct and redu,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11271,PHI:8018,UniProt,J9VUJ5,GenBank,AFR97903,,,H99,clr61 (CNAG_01699),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; calcofluor white; Congo red,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29581526,PubMed,10.1038/s41598-018-21965-y,Sci Rep.2018 Mar 26;8(1):5209,andrew.alspaugh@duke.edu,"Although most of the mutants showed some degree of reduced survival in macrophages, the Δhda1 mutant was the most attenuated, and the Δclr61 mutant demonstrated better survival compared to wild-type in this in vitro model of host-pathogen interaction.",F Brandão 2018,2018,7 genes,Brandao-2018-HDAC genes play distinct and redu,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11272,PHI:8012,UniProt,J9VU19,GenBank,AFR97768,,,H99,hda1 (CNAG_01563),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,histone deacetylase,,,,reduced virulence,yes,,,,,,,,,no,SDS; calcofluor white; Congo red,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29581526,PubMed,10.1038/s41598-018-21965-y,Sci Rep.2018 Mar 26;8(1):5209,andrew.alspaugh@duke.edu,"Although most of the mutants showed some degree of reduced survival in macrophages, the Δhda1 mutant was the most attenuated, and the Δclr61 mutant demonstrated better survival compared to wild-type in this in vitro model of host-pathogen interaction.",F Brandão 2018,2018,7 genes,Brandao-2018-HDAC genes play distinct and redu,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11273,PHI:8019,UniProt,A8YY71,GenBank,ABX30091,,,TCH1516,atpG,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,skin,F1F0 ATPase,,,,reduced virulence,,,,,,,,reduced,,no,"2,2'-dipyridyl; H2O2; kanamycin; vancomycin; chloramphenicol; tetracycline","2,2'-dipyridyl: CHEBI:30351; H2O2: CHEBI:16240; kanamycin: CHEBI:6104; vancomycin: CHEBI:28001; chloramphenicol: CHEBI:17698; tetracycline: CHEBI:27902",,,,,gene mutation; gene complementation,,,YVS,29554137,PubMed,10.1371/journal.ppat.1006907,PLoS Pathog.2018 Mar 19;14(3):e1006907,anthony.richardson@pitt.edu,ΔAtpG was attenuated during non-respiratory growth and was also sensitive to peroxide and kanamycin.,M R Grosser 2018,2018,1 gene,Grosser-2018-Genetic requirements for Staphylo,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11274,PHI:8020,UniProt,A5A9S7,GenBank,CAJ77700,,,CIP104536=ATCC19977,mmpL4a,,,,,,,36809,Mycobacteroides abscessus,,,pulmonary infection; cutaneo-mucous infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,brain,involved in glycopeptidolipids (GPL) synthesis and transport,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29594066,PubMed,10.3389/fcimb.2018.00069,Front Cell Infect Microbiol.2018 Mar 14;8:69,laurent.kremer@irim.cnrs.fr,"Low-level GPL producing mmpS4::pUX3 is more virulent than the S variant in zebra?sh embryos, but not as virulent as the R variant.",A Viljoen 2018,2018,1 gene,Viljoen-2018-A Simple and Rapid Gene Disruptio,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11275,PHI:8021,,no data found,GenBank,AAZ51929,,,MGAS5005,nagC,,,,,,,1314,Streptococcus pyogenes,293653,MGAS5005,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen,glucokinase,,,glucose transport pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29594067,PubMed,10.3389/fcimb.2018.00071,Front Cell Infect Microbiol.2018 Mar 14;8:71,kmciver@umd.edu,"The glucose metabolism through the PTS was important for survival in whole human blood whereas impaired glucose utilization in general led to the early production of Streptolysin S (SLS) toxin, resulting in more severe lesions in vivo.",G S Sundar 2018,2018,2 genes,Sundar-2018-Route of Glucose Uptake in the Gro,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11276,PHI:8022,UniProt,Q99Z66,GenBank,AAK34199,,,SF370,ptsI,,,,,,,1314,Streptococcus pyogenes,293653,MGAS5005,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen,phosphoenolpyruvate-protein phosphotransferase,,,glucose transport pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29594067,PubMed,10.3389/fcimb.2018.00071,Front Cell Infect Microbiol.2018 Mar 14;8:71,kmciver@umd.edu,"The glucose metabolism through the PTS was important for survival in whole human blood whereas impaired glucose utilization in general led to the early production of Streptolysin S (SLS) toxin, resulting in more severe lesions in vivo.",G S Sundar 2018,2018,2 genes,Sundar-2018-Route of Glucose Uptake in the Gro,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11277,PHI:8023,UniProt,A0A0H3NMH7,GenBank,CBW17966,,,SL1344,grhD1 (SL1344_1872),,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cecum; ileum,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29555922,PubMed,10.1038/s41598-018-23068-0,Sci Rep.2018 Mar 19;8(1):4841,victor@ibt.unam.mx,"The ΔgrhD1 mutant showed a reduction in the invasion of both HeLa cells, RAW264.7 mouse macrophages and NRK-49F fibroblasts in comparison to the WT strain.",M M Banda 2018,2018,1 gene,Banda-2018-HilD and PhoP independently regulat,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11278,PHI:8023,UniProt,A0A0H3NMH7,GenBank,CBW17966,,,SL1344,grhD1 (SL1344_1872),,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29555922,PubMed,10.1038/s41598-018-23068-0,Sci Rep.2018 Mar 19;8(1):4841,victor@ibt.unam.mx,"The ΔgrhD1 mutant showed a reduction in the invasion of both HeLa cells, RAW264.7 mouse macrophages and NRK-49F fibroblasts in comparison to the WT strain.",M M Banda 2018,2018,1 gene,Banda-2018-HilD and PhoP independently regulat,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11279,PHI:8024,UniProt,A0A0H3NG92,GenBank,CBW17434,,,SL1344,SseF,,,,SseG,UniProt: A0A0H3NB75; GenBank: CBW17435,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610274,PubMed,10.1074/jbc.M117.811737,J Biol Chem.2018 Apr 2. pii: jbc.M117.811737,6020100065@jsnu.edu.cn,"Host gene alteration data available for Rab1A. S. Typhimurium targeted the Rab1A-dependent pathogen-restriction pathway with two T3SS effector proteins, SseF and SseG, and the Rab1A-mediated autophagy pathway plays a crucial role in host defense against S. Typhimurium.",Z Z Feng 2018,2018,2 genes,Feng-2018-The _em_Salmonella__em_ effectors Ss,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11280,PHI:8025,UniProt,A0A0H3NB75,GenBank,CBW17435,,,SL1344,SseG,,,,SseF,UniProt: A0A0H3NG92; GenBank: CBW17434,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610274,PubMed,10.1074/jbc.M117.811737,J Biol Chem.2018 Apr 2. pii: jbc.M117.811737,6020100065@jsnu.edu.cn,"Host gene alteration data available for Rab1A. S. Typhimurium targeted the Rab1A-dependent pathogen-restriction pathway with two T3SS effector proteins, SseF and SseG, and the Rab1A-mediated autophagy pathway plays a crucial role in host defense against S. Typhimurium.",Z Z Feng 2018,2018,2 genes,Feng-2018-The _em_Salmonella__em_ effectors Ss,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11281,PHI:8026,UniProt,Q52432,GenBank,OPE56537,,,PT23,AvrRps4,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Kordaat,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29601603,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,gassmannw@missouri.edu,"AvrRps4N (133 amnio acids) in the absence of AvrRps4C (88 amnio acids) enhanceed virulence in Col-0, in addition, AvrRps4N triggered a hypersensitive response in lettuce that is attenuated by coexpression of AvrRps4C, further supporting the role of AvrRps4N as a bona fide effector domain.",M K Halane 2018,2018,2 genes,Halane-2018-The bacterial type III-secreted pr,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11282,PHI:8027,UniProt,Q88BH0,GenBank,AAO53599,,,DC3000,hopK1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Kordaat,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29601603,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,gassmannw@missouri.edu,"AvrRps4N (133 amnio acids) in the absence of AvrRps4C (88 amnio acids) enhanceed virulence in Col-0, in addition, AvrRps4N triggered a hypersensitive response in lettuce that is attenuated by coexpression of AvrRps4C, further supporting the role of AvrRps4N as a bona fide effector domain.",M K Halane 2018,2018,2 genes,Halane-2018-The bacterial type III-secreted pr,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11283,PHI:8026,UniProt,Q52432,GenBank,OPE56537,,,PT23,AvrRps4,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; other evidence: transgenic plants,,,YVS,29601603,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,gassmannw@missouri.edu,"AvrRps4N (133 amnio acids) in the absence of AvrRps4C (88 amnio acids) enhanceed virulence in Col-0, in addition, AvrRps4N triggered a hypersensitive response in lettuce that is attenuated by coexpression of AvrRps4C, further supporting the role of AvrRps4N as a bona fide effector domain.",M K Halane 2018,2018,2 genes,Halane-2018-The bacterial type III-secreted pr,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11284,PHI:8027,UniProt,Q88BH0,GenBank,AAO53599,,,DC3000,hopK1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29601603,PubMed,10.1371/journal.ppat.1006984,PLoS Pathog. 2018 Mar 30;14(3):e1006984,gassmannw@missouri.edu,"AvrRps4N (133 amnio acids) in the absence of AvrRps4C (88 amnio acids) enhanceed virulence in Col-0, in addition, AvrRps4N triggered a hypersensitive response in lettuce that is attenuated by coexpression of AvrRps4C, further supporting the role of AvrRps4N as a bona fide effector domain.",M K Halane 2018,2018,2 genes,Halane-2018-The bacterial type III-secreted pr,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11285,PHI:8028,UniProt,Q8MPM3,GenBank,CAD20572,,,,Tkt,,,,,,,5665,Leishmania mexicana,,M379,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,popliteal lymph node,transketolase,,,pentose phosphate pathway,loss of pathogenicity,,,,,,,,wild type,,no,methylene blue; paromomycin; potassium antimonyl tartrate; H2O2; miltefosine; pentamidine,methylene blue: CHEBI:6872; paromomycin: CHEBI:7934; potassium antimonyl tartrate: CAS:28300-74-5; H2O2: CHEBI:16240; miltefosine: CHEBI:75283; pentamidine: CHEBI:45081,,,,,gene deletion: full; gene complementation,,,YVS,29554142,PubMed,10.1371/journal.ppat.1006953,PLoS Pathog. 2018 Mar 19;14(3):e1006953,michael.barrett@glasgow.ac.uk,"ΔTkt promastigotes were more susceptible to oxidative stress and various leishmanicidal drugs than wild-type, in addition to changes consistent with those directly related to the role of TKT in the PPP, central carbon metabolism was substantially decreased, the cells consumed significantly less glucose, flux through glycolysis diminished, and production of the main end products of metabolismwas decreased.",J Kovářová 2018,2018,1 gene,Kovarova-2018-Deletion of transketolase trigge,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11286,PHI:8028,UniProt,Q8MPM3,GenBank,CAD20572,,,,Tkt,,,,,,,5665,Leishmania mexicana,,M379,leishmaniasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,transketolase,,,pentose phosphate pathway,loss of pathogenicity,,,,,,,,wild type,,no,methylene blue; paromomycin; potassium antimonyl tartrate; H2O2; miltefosine; pentamidine,methylene blue: CHEBI:6872; paromomycin: CHEBI:7934; potassium antimonyl tartrate: CAS:28300-74-5; H2O2: CHEBI:16240; miltefosine: CHEBI:75283; pentamidine: CHEBI:45081,,,,,gene deletion: full; gene complementation,,,YVS,29554142,PubMed,10.1371/journal.ppat.1006953,PLoS Pathog. 2018 Mar 19;14(3):e1006953,michael.barrett@glasgow.ac.uk,"ΔTkt promastigotes were more susceptible to oxidative stress and various leishmanicidal drugs than wild-type, in addition to changes consistent with those directly related to the role of TKT in the PPP, central carbon metabolism was substantially decreased, the cells consumed significantly less glucose, flux through glycolysis diminished, and production of the main end products of metabolism was decreased.",J Kovářová 2018,2018,1 gene,Kovarova-2018-Deletion of transketolase trigge,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11287,PHI:8029,UniProt,Q59VG6,GenBank,AOW26151,,,SC5314,ERG3,chromosome 1,,,,,,5476,Candida albicans,,CAF2-1,oropharyngeal candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue epithelium,C-5 sterol desaturase,,,ergosterol biosynthesis pathway,loss of pathogenicity,,,,,,,,,,no,fluconazole,"fluconazole: CHEBI:46081, CAS:86386-73-4",,,,,gene deletion: full,,,YVS,29555898,PubMed,10.1038/s41368-018-0013-2,Int J Oral Sci. 2018 Mar 16;10(2):9,zhouxd@scu.edu.cn,"The erg3Δ/Δ and erg11Δ/Δ strains co-cultured with epithelial cells significantly reduced the adhesion, damage, and cytokine (interleukin-1a (IL-1a)) production, whereas the invasion was not affected in vitro.",Y Zhou 2018,2018,2 genes,Zhou-2018-ERG3 and ERG11 genes are critical fo,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11288,PHI:8030,UniProt,P10613,GenBank,ACF34636,,,CA95,ERG11,chromosome 5,,,,,,5476,Candida albicans,,CAF2-1,oropharyngeal candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue epithelium,lanosterol 14-alpha demethylase,,,ergosterol biosynthesis pathway,loss of pathogenicity,,,,,,,,,,no,fluconazole,"fluconazole: CHEBI:46081, CAS:86386-73-4",,,,,gene deletion: full,,,YVS,29555898,PubMed,10.1038/s41368-018-0013-2,Int J Oral Sci. 2018 Mar 16;10(2):9,zhouxd@scu.edu.cn,"The erg3Δ/Δ and erg11Δ/Δ strains co-cultured with epithelial cells significantly reduced the adhesion, damage, and cytokine (interleukin-1a (IL-1a)) production, whereas the invasion was not affected in vitro.",Y Zhou 2018,2018,2 genes,Zhou-2018-ERG3 and ERG11 genes are critical fo,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11289,PHI:8031,UniProt,Q9RGS9,GenBank,AF105339_1,,,DNM2,HmbR,,,,,,,487,Neisseria meningitidis,,"Norman B:14:P1.7,16",meningococcal infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; spleen,hemoglobin receptor,,,,increased virulence (hypervirulence),,,,,,,,,,no,desferal,desferal: CHEBI:31460,,,,,other evidence: transgenic,,,YVS,29638173,PubMed,10.1080/21505594.2018.1460064,Virulence. 2018 Apr 11:1-18,mktaha@pasteur.fr,"Bacteria and macrophages were only observed in the spleen of mice infected with a phase variant capsulated carriage isolate ""hmbR-ON"", underlying their global enhanced virulence and their capacity to exceed the spleen phagocytosis ability.",J Sevestre 2018,2018,1 gene,Sevestre-2018-Differential expression of hemog,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11290,PHI:8032,UniProt,Q5GWK1,GenBank,AAW76920,,,KACC10331,PhoB,,,,,,PHI:8033,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,two-component signal transduction system response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29575480,PubMed,10.1111/mpp.12680,Mol Plant Pathol. 2018 Mar 25,ruanlifang@mail.hzau.edu.cn,"Growth in phosphate-rich medium and virulence on host rice were reduced in the phoR-deleted mutant, whereas these phenotypes were not affected by the absence of phoB or phoBR.",D Zheng 2018,2018,2 genes,Zheng-2018-Activation of PhoBR under phosphate,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11291,PHI:8033,UniProt,Q5GWK0,GenBank,AAW76921,,,KACC10331,PhoR,,,,,,PHI:8032,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,two-component signal transduction system histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29575480,PubMed,10.1111/mpp.12680,Mol Plant Pathol. 2018 Mar 25,ruanlifang@mail.hzau.edu.cn,"Growth in phosphate-rich medium and virulence on host rice were reduced in the phoR-deleted mutant, whereas these phenotypes were not affected by the absence of phoB or phoBR.",D Zheng 2018,2018,2 genes,Zheng-2018-Activation of PhoBR under phosphate,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11292,PHI:8032,UniProt,Q5GWK1,GenBank,AAW76920,,,KACC10331,PhoB,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,two-component signal transduction system response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29575480,PubMed,10.1111/mpp.12680,Mol Plant Pathol. 2018 Mar 25,ruanlifang@mail.hzau.edu.cn,"Growth in phosphate-rich medium and virulence on host rice were reduced in the phoR-deleted mutant, whereas these phenotypes were not affected by the absence of phoB or phoBR.",D Zheng 2018,2018,2 genes,Zheng-2018-Activation of PhoBR under phosphate,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11293,PHI:8033,UniProt,Q5GWK0,GenBank,AAW76921,,,KACC10331,PhoR,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Minghui 63,,,leaf,two-component signal transduction system histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29575480,PubMed,10.1111/mpp.12680,Mol Plant Pathol. 2018 Mar 25,ruanlifang@mail.hzau.edu.cn,"Growth in phosphate-rich medium and virulence on host rice were reduced in the phoR-deleted mutant, whereas these phenotypes were not affected by the absence of phoB or phoBR.",D Zheng 2018,2018,2 genes,Zheng-2018-Activation of PhoBR under phosphate,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11294,PHI:8034,UniProt,A6RPU4,GenBank,XP_001558833,,,B05.10,BcATG8,chromosome 2,,,BcATG4,UniProt: A6SDQ3; GenBank: EMR82201,,40559,Botrytis cinerea,,BY4741,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29572212,PubMed,10.1128/AEM.02455-17,Appl Environ Microbiol. 2018 Mar 23. pii: AEM.02455-17,jinkui960@ynu.edu.cn,"Deletion of BcATG8 (ΔBcAtg8) blocked autophagy and significantly impaired mycelial growth, conidiation, sclerotial formation and virulence.",W Ren 2018,2018,1 gene,Ren-2018-The autophagy gene BcATG8 regulates v,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11295,PHI:8034,UniProt,A6RPU4,GenBank,XP_001558833,,,B05.10,BcATG8,chromosome 2,,,BcATG4,UniProt: A6SDQ3; GenBank: EMR82201,,40559,Botrytis cinerea,,BY4741,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29572212,PubMed,10.1128/AEM.02455-17,Appl Environ Microbiol. 2018 Mar 23. pii: AEM.02455-17,jinkui960@ynu.edu.cn,"Deletion of BcATG8 (ΔBcAtg8) blocked autophagy and significantly impaired mycelial growth, conidiation, sclerotial formation and virulence.",W Ren 2018,2018,1 gene,Ren-2018-The autophagy gene BcATG8 regulates v,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11296,PHI:8034,UniProt,A6RPU4,GenBank,XP_001558833,,,B05.10,BcATG8,chromosome 2,,,BcATG4,UniProt: A6SDQ3; GenBank: EMR82201,,40559,Botrytis cinerea,,BY4741,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29572212,PubMed,10.1128/AEM.02455-17,Appl Environ Microbiol. 2018 Mar 23. pii: AEM.02455-17,jinkui960@ynu.edu.cn,"Deletion of BcATG8 (ΔBcAtg8) blocked autophagy and significantly impaired mycelial growth, conidiation, sclerotial formation and virulence.",W Ren 2018,2018,1 gene,Ren-2018-The autophagy gene BcATG8 regulates v,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11297,PHI:8034,UniProt,A6RPU4,GenBank,XP_001558833,,,B05.10,BcATG8,chromosome 2,,,BcATG4,UniProt: A6SDQ3; GenBank: EMR82201,,40559,Botrytis cinerea,,BY4741,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29572212,PubMed,10.1128/AEM.02455-17,Appl Environ Microbiol. 2018 Mar 23. pii: AEM.02455-17,jinkui960@ynu.edu.cn,"Deletion of BcATG8 (ΔBcAtg8) blocked autophagy and significantly impaired mycelial growth, conidiation, sclerotial formation and virulence.",W Ren 2018,2018,1 gene,Ren-2018-The autophagy gene BcATG8 regulates v,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11298,PHI:8035,UniProt,G1X6F2,GenBank,EGX51376,,,ATCC 24927,AoRab-7A (AOL_s00054g446),,,,,,,2813651,Orbilia oligospora,756982,CBS 115.81,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,Rab GTPase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,H2O2; NaCl; sodium dodecyl sulfate,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full,,,YVS,29616315,PubMed,10.1007/s00253-018-8929-1,Appl Microbiol Biotechnol. 2018 Apr 3,jinkui960@ynu.edu.cn,"There was no significant difference in morphology and number of traps between the ΔAoRab-2 mutantsand the WT strain, however, none of the nematodes were captured by the ΔAoRab-7A mutants. Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.",X Yang 2018,2018,2 genes,Yang-2018-Two Rab GTPases play different roles,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11299,PHI:8036,UniProt,G1X666,GenBank,EGX51290,,,ATCC 24927,AoRab-2 (AOL_s00054g360),,,,,,,2813651,Orbilia oligospora,756982,CBS 115.81,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,Rab GTPase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,H2O2; NaCl; sodium dodecyl sulfate,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full,,,YVS,29616315,PubMed,10.1007/s00253-018-8929-1,Appl Microbiol Biotechnol. 2018 Apr 3,jinkui960@ynu.edu.cn,"There was no significant difference in morphology and number of traps between the ΔAoRab-2 mutantsand the WT strain, however, none of the nematodes were captured by the ΔAoRab-7A mutants. Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.",X Yang 2018,2018,2 genes,Yang-2018-Two Rab GTPases play different roles,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11300,PHI:8037,UniProt,W7MGE8,GenBank,EWG49946,,,7600,Fvlds1,chromosome 5,,,,,,117187,Fusarium verticillioides,,ITEM 10027,stalk rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,kernel,linoleate diol synthase 1,,,,reduced virulence,,,,,,increased,,,,no,,,,,,,gene deletion: full,,,YVS,29660236,PubMed,10.1111/mpp.12690,Mol Plant Pathol. 2018 Apr 16,kolomiets@tamu.edu,"Host gene alteration data available for lox3, lox4, lox5 and lox12. The ability of ΔFvlds1D mutant strain to colonize seed and produce fumonisin remained significantly impaired compared to the FvWT strain.",P Battilani 2018,2018,1 gene,Battilani-2018-OXYLIPINS FROM BOTH PATHOGEN AN,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11301,PHI:8038,UniProt,G4MPJ3,GenBank,EHA58036,,,70-15,Mosmt3,chromosome 1,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,yes,,,,reduced,,,reduced,no,hydroxyurea; methyl methanesulfonate; H2O2; methyl viologen,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,29633464,PubMed,10.1111/mpp.12687,Mol Plant Pathol. 2018 Apr 6,yonglee@snu.ac.kr,"Deletion mutants for each of the four genes were viable, but showed significant defects in mycelial growth, conidiation, septum formation, conidial germination, appressorium formation and pathogenicity.",Y J Lim 2018,2018,4 genes,Lim-2018-SUMOylation is required for fungal de,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11302,PHI:8039,UniProt,G4MUG1,GenBank,EHA54848,,,70-15,Moaos1,chromosome 2,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,yes,,,,reduced,,,reduced,no,hydroxyurea; methyl methanesulfonate; H2O2; methyl viologen,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,29633464,PubMed,10.1111/mpp.12687,Mol Plant Pathol. 2018 Apr 6,yonglee@snu.ac.kr,"Deletion mutants for each of the four genes were viable, but showed significant defects in mycelial growth, conidiation, septum formation, conidial germination, appressorium formation and pathogenicity.",Y J Lim 2018,2018,4 genes,Lim-2018-SUMOylation is required for fungal de,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11303,PHI:8040,UniProt,G4MLK2,GenBank,EHA56835,,,70-15,Mouba2,chromosome 1,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,yes,,,,reduced,,,reduced,no,hydroxyurea; methyl methanesulfonate; H2O2; methyl viologen,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,29633464,PubMed,10.1111/mpp.12687,Mol Plant Pathol. 2018 Apr 6,yonglee@snu.ac.kr,"Deletion mutants for each of the four genes were viable, but showed significant defects in mycelial growth, conidiation, septum formation, conidial germination, appressorium formation and pathogenicity.",Y J Lim 2018,2018,4 genes,Lim-2018-SUMOylation is required for fungal de,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11304,PHI:8039,UniProt,G4MUG1,GenBank,EHA54848,,,70-15,Moaos1,chromosome 2,,,,,PHI:8040,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,yes,,,,reduced,,,reduced,no,hydroxyurea; methyl methanesulfonate; H2O2; methyl viologen,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,29633464,PubMed,10.1111/mpp.12687,Mol Plant Pathol. 2018 Apr 6,yonglee@snu.ac.kr,"Deletion mutants for each of the four genes were viable, but showed significant defects in mycelial growth, conidiation, septum formation, conidial germination, appressorium formation and pathogenicity.",Y J Lim 2018,2018,4 genes,Lim-2018-SUMOylation is required for fungal de,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11305,PHI:8040,UniProt,G4MLK2,GenBank,EHA56835,,,70-15,Mouba2,chromosome 1,,,,,PHI:8039,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,yes,,,,reduced,,,reduced,no,hydroxyurea; methyl methanesulfonate; H2O2; methyl viologen,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,29633464,PubMed,10.1111/mpp.12687,Mol Plant Pathol. 2018 Apr 6,yonglee@snu.ac.kr,"Deletion mutants for each of the four genes were viable, but showed significant defects in mycelial growth, conidiation, septum formation, conidial germination, appressorium formation and pathogenicity.",Y J Lim 2018,2018,4 genes,Lim-2018-SUMOylation is required for fungal de,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11306,PHI:8041,UniProt,G4ND54,GenBank,EHA48396,,,70-15,Moubc9,chromosome 5,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,yes,,,,reduced,,,reduced,no,hydroxyurea; methyl methanesulfonate; H2O2; methyl viologen,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,29633464,PubMed,10.1111/mpp.12687,Mol Plant Pathol. 2018 Apr 6,yonglee@snu.ac.kr,"Deletion mutants for each of the four genes were viable, but showed significant defects in mycelial growth, conidiation, septum formation, conidial germination, appressorium formation and pathogenicity.",Y J Lim 2018,2018,4 genes,Lim-2018-SUMOylation is required for fungal de,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11307,PHI:8042,UniProt,B2I2B5,GenBank,ACC58902,,,ACICU,lpxA,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung; kidney,N-acetylglucosamine-1-phosphate uridyltransferase,,,lipopolysaccharide (LPS) biosynthesis,reduced virulence,,,,,,,,reduced,,no,chlorhexidine; deoxycholate; sodium dodecyl sulfate; ethanol; povidone iodine,chlorhexidine: CHEBI:3614; deoxycholate: CHEBI:23614; sodium dodecyl sulfate: CHEBI:8984; ethanol: CHEBI:16236; povidone-iodine: CHEBI:8347,,,,,gene mutation; gene complementation,,,YVS,29638177,PubMed,10.1080/21505594.2018.1460187,Virulence. 2018 Apr 11:1-43,mcconnell.mike75@gmail.com,"LPS loss also significantly affected biofilm production, surface motility, growth under iron limitation and susceptibility to multiple disinfectants used in the clinical setting.",M Carretero-Ledesma 2018,2018,1 gene,Carretero-Ledes-2018-Phenotypic Changes Associ,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11308,PHI:8043,UniProt,E9NQ06,GenBank,ADV39930,,,2627,GntR,,,,,,,1307,Streptococcus suis,218494,P1/7,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver,helix-turn-helix (HTH) DNA binding protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29635445,PubMed,10.1093/femsle/fny091,FEMS Microbiol Lett. 2018 Apr 7,lijinquan2007@gmail.com,The results showed that isogenic deletion mutant and an isogenic single-nucleotide substitution mutant of P1/7 gntR had a stronger ability to tolerate the oxidative stress and reproduce in blood.,Y Zhou 2018,2018,1 gene,Zhou-2018-GntR is involved in the expression o,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11309,PHI:8043,UniProt,E9NQ06,GenBank,ADV39930,,,2627,GntR,,Ala407Thr,,,,,1307,Streptococcus suis,218494,P1/7,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver,helix-turn-helix (HTH) DNA binding protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,29635445,PubMed,10.1093/femsle/fny091,FEMS Microbiol Lett. 2018 Apr 7,lijinquan2007@gmail.com,The results showed that isogenic deletion mutant and an isogenic single-nucleotide substitution mutant of P1/7 gntR had a stronger ability to tolerate the oxidative stress and reproduce in blood.,Y Zhou 2018,2018,1 gene,Zhou-2018-GntR is involved in the expression o,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11310,PHI:8044,UniProt,J4UEM9,GenBank,EJP60722,,,ARSEF 2860,hos2,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone deacetylase,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,H2O2; Congo red; NaCl; KCl; menadione; hydroxyurea; trichostatin A; methyl methanesulfonate (MMS),H2O2: CHEBI:16240; Congo red: CHEBI:34653; NaCl: CHEBI:267101; KCl: CHEBI:32588; menadione: CHEBI:28869; hydroxyurea: CHEBI:44423; trichostatin A: CHEBI:46024; methyl methanesulfonate (MMS): CHEBI:25255,,,,,gene deletion: full; gene complementation,,,YVS,29543404,PubMed,10.1111/cmi.12839,Cell Microbiol. 2018 Mar 15:e12839,mgfeng@zju.edu.cn,"The Δhos2 mutant suffered increased sensitivities to DNA-damaging and oxidative stresses, disturbed cell cycle, impeded cytokinesis, increased cell size or length, reduced conidiation capacity, altered conidial properties, and attenuated virulence.",Q Cai 2018,2018,1 gene,Cai-2018-Pleiotropic effects of the histone de,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11311,PHI:8045,UniProt,G4MPJ3,GenBank,EHA58036,,,70-15,Smt3,chromosome 1,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Lijiangxintuanheigu,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate (SDS); H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29663402,PubMed,10.1111/nph.15141,New Phytol. 2018 Apr 16,chenxiaolin@mail.hzau.edu.cn,Mutation of consensus sumoylation sites in each septin all resulted in reduced virulence to the host and dislocation of septins in appressoria.,C Liu 2018,2018,5 genes,Liu-2018-Global analysis of sumoylation functi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11312,PHI:8046,UniProt,G4MUG1,GenBank,EHA54848,,,70-15,Aos1,chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Lijiangxintuanheigu,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate (SDS); H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29663402,PubMed,10.1111/nph.15141,New Phytol. 2018 Apr 16,chenxiaolin@mail.hzau.edu.cn,Mutation of consensus sumoylation sites in each septin all resulted in reduced virulence to the host and dislocation of septins in appressoria.,C Liu 2018,2018,5 genes,Liu-2018-Global analysis of sumoylation functi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11313,PHI:8047,UniProt,G4MLK2,GenBank,EHA56835,,,70-15,Uba2,chromosome 1,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Lijiangxintuanheigu,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate (SDS); H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29663402,PubMed,10.1111/nph.15141,New Phytol. 2018 Apr 16,chenxiaolin@mail.hzau.edu.cn,Mutation of consensus sumoylation sites in each septin all resulted in reduced virulence to the host and dislocation of septins in appressoria.,C Liu 2018,2018,5 genes,Liu-2018-Global analysis of sumoylation functi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11314,PHI:8048,UniProt,G4ND54,GenBank,EHA48396,,,70-15,Ubc9,chromosome 5,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Lijiangxintuanheigu,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate (SDS); H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29663402,PubMed,10.1111/nph.15141,New Phytol. 2018 Apr 16,chenxiaolin@mail.hzau.edu.cn,Mutation of consensus sumoylation sites in each septin all resulted in reduced virulence to the host and dislocation of septins in appressoria.,C Liu 2018,2018,5 genes,Liu-2018-Global analysis of sumoylation functi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11315,PHI:8049,UniProt,G4MV34,GenBank,EHA54049,,,70-15,Siz1,chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Lijiangxintuanheigu,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate (SDS); H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29663402,PubMed,10.1111/nph.15141,New Phytol. 2018 Apr 16,chenxiaolin@mail.hzau.edu.cn,Mutation of consensus sumoylation sites in each septin all resulted in reduced virulence to the host and dislocation of septins in appressoria.,C Liu 2018,2018,5 genes,Liu-2018-Global analysis of sumoylation functi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11316,PHI:8045,UniProt,G4MPJ3,GenBank,EHA58036,,,70-15,Smt3,chromosome 1,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate (SDS); H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29663402,PubMed,10.1111/nph.15141,New Phytol. 2018 Apr 16,chenxiaolin@mail.hzau.edu.cn,Mutation of consensus sumoylation sites in each septin all resulted in reduced virulence to the host and dislocation of septins in appressoria.,C Liu 2018,2018,5 genes,Liu-2018-Global analysis of sumoylation functi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11317,PHI:8046,UniProt,G4MUG1,GenBank,EHA54848,,,70-15,Aos1,chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate (SDS); H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29663402,PubMed,10.1111/nph.15141,New Phytol. 2018 Apr 16,chenxiaolin@mail.hzau.edu.cn,Mutation of consensus sumoylation sites in each septin all resulted in reduced virulence to the host and dislocation of septins in appressoria.,C Liu 2018,2018,5 genes,Liu-2018-Global analysis of sumoylation functi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11318,PHI:8047,UniProt,G4MLK2,GenBank,EHA56835,,,70-15,Uba2,chromosome 1,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate (SDS); H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29663402,PubMed,10.1111/nph.15141,New Phytol. 2018 Apr 16,chenxiaolin@mail.hzau.edu.cn,Mutation of consensus sumoylation sites in each septin all resulted in reduced virulence to the host and dislocation of septins in appressoria.,C Liu 2018,2018,5 genes,Liu-2018-Global analysis of sumoylation functi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11319,PHI:8048,UniProt,G4ND54,GenBank,EHA48396,,,70-15,Ubc9,chromosome 5,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate (SDS); H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29663402,PubMed,10.1111/nph.15141,New Phytol. 2018 Apr 16,chenxiaolin@mail.hzau.edu.cn,Mutation of consensus sumoylation sites in each septin all resulted in reduced virulence to the host and dislocation of septins in appressoria.,C Liu 2018,2018,5 genes,Liu-2018-Global analysis of sumoylation functi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11320,PHI:8049,UniProt,G4MV34,GenBank,EHA54049,,,70-15,Siz1,chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,SUMOylation-associated protein,,,small ubiquitin-like modifier (SUMO) pathway,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate (SDS); H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29663402,PubMed,10.1111/nph.15141,New Phytol. 2018 Apr 16,chenxiaolin@mail.hzau.edu.cn,Mutation of consensus sumoylation sites in each septin all resulted in reduced virulence to the host and dislocation of septins in appressoria.,C Liu 2018,2018,5 genes,Liu-2018-Global analysis of sumoylation functi,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11321,PHI:8050,UniProt,Q44135,GenBank,AAB64445,,,J45,cpxA,,,,,,PHI:8051,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,sensor histidine kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29662838,PubMed,10.3389/fcimb.2018.00072,Front Cell Infect Microbiol. 2018 Mar 20;8:72,beiwc@mail.hzau.edu.cn,CpxA/CpxR contributed to the biofilm formation ability of A. pleuropneumoniae.,H Li 2018,2018,2 genes,Li-2018-The CpxA_CpxR Two-Component System Aff,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11322,PHI:8051,UniProt,E0E7B4,GenBank,EFM85766,,,4074,cpxR,,,,,,PHI:8050,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29662838,PubMed,10.3389/fcimb.2018.00072,Front Cell Infect Microbiol. 2018 Mar 20;8:72,beiwc@mail.hzau.edu.cn,CpxA/CpxR contributed to the biofilm formation ability of A. pleuropneumoniae.,H Li 2018,2018,2 genes,Li-2018-The CpxA_CpxR Two-Component System Aff,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11323,PHI:8052,UniProt,G2XDS1,GenBank,XP_009658323,,,VdLs.17,Vdmyo5,,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,myosin,,,,reduced virulence,,no,no,,,reduced; aberrant,,reduced; aberrant,,no,calcoflour white,calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,29575486,PubMed,10.1111/1462-2920.14101,Environ Microbiol. 2018 Apr;20(4):1607-1621,zskong@im.ac.cn,"The VdMyo5 deletion mutant (ΔVdmyo5) fungi showed obvious defects in the development of conidia and the polarized elongation of vegetative hyphae, but no inhibition of host root penetration.",Z Feng 2018,2018,1 gene,Feng-2018-The Myosin5-mediated actomyosin moti,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11324,PHI:8052,UniProt,G2XDS1,GenBank,XP_009658323,,,VdLs.17,Vdmyo5,,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia,,,leaf,myosin,,,,reduced virulence,,no,no,,,reduced; aberrant,,reduced; aberrant,,no,calcoflour white,calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,29575486,PubMed,10.1111/1462-2920.14101,Environ Microbiol. 2018 Apr;20(4):1607-1621,zskong@im.ac.cn,"The VdMyo5 deletion mutant (ΔVdmyo5) fungi showed obvious defects in the development of conidia and the polarized elongation of vegetative hyphae, but no inhibition of host root penetration.",Z Feng 2018,2018,1 gene,Feng-2018-The Myosin5-mediated actomyosin moti,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11325,PHI:8053,UniProt,L7NCS1,GenBank,AEJ88241,,,,Pc11951,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11326,PHI:8054,UniProt,A0A2R2Z552,GenBank,AUD40034,,,Pc537,Pc107869,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11327,PHI:8055,UniProt,A0A2R2Z560,GenBank,AUD40033,,,Pc537,Pc109095,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11328,PHI:8056,UniProt,A0A2R2Z570,GenBank,AUD40035,,,Pc537,Pc109174,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11329,PHI:8057,UniProt,A0A2R2Z561,GenBank,AUD40036,,,Pc537,Pc118356,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11330,PHI:8058,UniProt,A0A2R2Z564,GenBank,AUD40032,,,Pc537,Pc118551,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11331,PHI:8059,UniProt,A0A2R2Z575,GenBank,AUD40037,,,Pc537,Pc121494,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11332,PHI:8060,UniProt,A0A2R2Z574,GenBank,AUD40038,,,Pc537,Pc129485,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11333,PHI:8061,UniProt,L7NCR0,GenBank,AEJ88232,,,,Pc129892,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11334,PHI:8062,UniProt,A0A2R2Z572,GenBank,AUD40039,,,Pc537,Pc553546,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11335,PHI:8053,UniProt,L7NCS1,GenBank,AEJ88241,,,,Pc11951,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Hanyu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11336,PHI:8054,UniProt,A0A2R2Z552,GenBank,AUD40034,,,Pc537,Pc107869,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Hanyu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11337,PHI:8055,UniProt,A0A2R2Z560,GenBank,AUD40033,,,Pc537,Pc109095,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Hanyu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11338,PHI:8056,UniProt,A0A2R2Z570,GenBank,AUD40035,,,Pc537,Pc109174,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Hanyu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11339,PHI:8057,UniProt,A0A2R2Z561,GenBank,AUD40036,,,Pc537,Pc118356,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Hanyu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11340,PHI:8058,UniProt,A0A2R2Z564,GenBank,AUD40032,,,Pc537,Pc118551,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Hanyu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11341,PHI:8059,UniProt,A0A2R2Z575,GenBank,AUD40037,,,Pc537,Pc121494,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Hanyu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11342,PHI:8060,UniProt,A0A2R2Z574,GenBank,AUD40038,,,Pc537,Pc129485,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Hanyu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11343,PHI:8061,UniProt,L7NCR0,GenBank,AEJ88232,,,,Pc129892,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Hanyu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11344,PHI:8062,UniProt,A0A2R2Z572,GenBank,AUD40039,,,Pc537,Pc553546,,,,,,,4784,Phytophthora capsici,,Pc537,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Hanyu,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29572661,PubMed,10.1007/s00438-018-1432-7,Mol Genet Genomics. 2018 Mar 23,xrchen@yzu.edu.cn,"Full-length Pc11951, Pc107869, Pc109174 and Pc118548 possessed phytotoxic activity, whereas the remaining P. capsici NLPs did not.",X R Chen 2018,2018,10 genes,Chen-2018-Identification and functional analys,BATCH_081,2018-04-01,MC,,,,,,,,,,,,,
,,Record 11345,PHI:8063,UniProt,A0A098DRQ4,GenBank,CEF84540,,,PH-1,FgSnx41 (FGSG_16745),chromosome 4,,,FgSnx4,UniProt: I1RXT2; GenBank: CEF84195,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,flower,sorting nexin protein,,,,reduced virulence,,,,,,wild type,wild type,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29676464,PubMed,10.1111/nph.15178,New Phytol. 2018 Apr 20,wenhuiz@fafu.edu.cn,"In the absence of FgSnx41 or FgSnx4, FgSnc1 is missorted and degraded in the vacuole, and null deletion of either component causes defects in the fungal polarized growth and virulence.",W Zheng 2018,2018,2 genes,Zheng-2018-The endosomal recycling of FgSnc1 b,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11346,PHI:8064,UniProt,I1RXT2,GenBank,CEF84195,,,PH-1,FgSnx4 (FGSG_09157),chromosome 4,,,FgSnx41,UniProt: A0A098DRQ4; GenBank: CEF84540,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,flower,sorting nexin protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29676464,PubMed,10.1111/nph.15178,New Phytol. 2018 Apr 20,wenhuiz@fafu.edu.cn,"In the absence of FgSnx41 or FgSnx4, FgSnc1 is missorted and degraded in the vacuole, and null deletion of either component causes defects in the fungal polarized growth and virulence.",W Zheng 2018,2018,2 genes,Zheng-2018-The endosomal recycling of FgSnc1 b,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11347,PHI:8065,UniProt,Q03456,GenBank,AAC05679,,,PAO1,fur,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ferric uptake regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,28847923,PubMed,10.1128/JB.00472-17,J Bacteriol. 2017 Oct 17;199(22). pii: e00472-17,francesco.imperi@uniroma1.it,"By investigating a P. aeruginosa conditional fur mutant, it was demonstrated that Fur was not essential for P. aeruginosa growth in liquid media, biofilm formation, and pathogenicity in an insect model of infection, conversely, Fur was essential for growth on solid media since Fur-depleted cells were severely impaired in colony formation.",M Pasqua 2017,2017,2 genes,Pasqua-2017-The ferric uptake regulator Fur is,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11348,PHI:8066,UniProt,Q51368,GenBank,AAG08916,,,PAO1,tonB1,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28847923,PubMed,10.1128/JB.00472-17,J Bacteriol. 2017 Oct 17;199(22). pii: e00472-17,francesco.imperi@uniroma1.it,"By investigating a P. aeruginosa conditional fur mutant, it was demonstrated that Fur was not essential for P. aeruginosa growth in liquid media, biofilm formation, and pathogenicity in an insect model of infection, conversely, Fur was essential for growth on solid media since Fur-depleted cells were severely impaired in colony formation.",M Pasqua 2017,2017,2 genes,Pasqua-2017-The ferric uptake regulator Fur is,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11349,PHI:8067,UniProt,Q7WQW5,GenBank,CAE30708,,,RB50,lmp1 (bb0210),,lacking C-terminal region,,htrA,UniProt: O51131; GenBank: AAC66500,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin; heart; joint; bladder,uracil-DNA glycosylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29749010,PubMed,10.1111/cmi.12855,Cell Microbiol. 2018 May 10:e12855,upal@umd.edu,"The studies suggested that, while each Lmp1 domain independently supported B. burgdorferi infectivity, function of full-length protein was required for optimal microbial persistence in the host.",X Zhuang 2018,2018,1 gene,Zhuang-2018-Borrelia burgdorferi surface-locat,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11350,PHI:8067,UniProt,Q7WQW5,GenBank,CAE30708,,,RB50,lmp1 (bb0210),,,,htrA,UniProt: O51131; GenBank: AAC66500,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin; heart; joint; bladder,uracil-DNA glycosylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29749010,PubMed,10.1111/cmi.12855,Cell Microbiol. 2018 May 10:e12855,upal@umd.edu,"The studies suggested that, while each Lmp1 domain independently supported B. burgdorferi infectivity, function of full-length protein was required for optimal microbial persistence in the host.",X Zhuang 2018,2018,1 gene,Zhuang-2018-Borrelia burgdorferi surface-locat,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11351,PHI:8067,UniProt,Q7WQW5,GenBank,CAE30708,,,RB50,lmp1 (bb0210),,lacking C-terminal region,,htrA,UniProt: O51131; GenBank: AAC66500,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,uracil-DNA glycosylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29749010,PubMed,10.1111/cmi.12855,Cell Microbiol. 2018 May 10:e12855,upal@umd.edu,Both N-terminal and middle regions of Lmp1 was necessary for spirochete transmission from ticks to mice.,X Zhuang 2018,2018,1 gene,Zhuang-2018-Borrelia burgdorferi surface-locat,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11352,PHI:8067,UniProt,Q7WQW5,GenBank,CAE30708,,,RB50,lmp1 (bb0210),,,,htrA,UniProt: O51131; GenBank: AAC66500,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,uracil-DNA glycosylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29749010,PubMed,10.1111/cmi.12855,Cell Microbiol. 2018 May 10:e12855,upal@umd.edu,Both N-terminal and middle regions of Lmp1 was necessary for spirochete transmission from ticks to mice.,X Zhuang 2018,2018,1 gene,Zhuang-2018-Borrelia burgdorferi surface-locat,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11353,PHI:8068,UniProt,A0A0D1C5E3,GenBank,XP_011389576,,,521,cce1 (UMAG_12197),chromosome 7,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. EGB,,,leaf,effector protein,,,,effector (plant avirulence determinant),,no,no,,,,,,,no,Congo red; calcofluor white; H2O2; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene mutation; gene complementation,,,YVS,29745456,PubMed,10.1111/mpp.12698,Mol Plant Pathol. 2018 May 10,armin.djamei@gmi.oeaw.ac.at,ΔCce1 mutants were blocked at early stages of infection and induce callose deposition as a plant defense response.,D Seitner 2018,2018,1 gene,Seitner-2018-The Core Effector Cce1 is Require,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11354,PHI:8069,UniProt,A0Q5P2,GenBank,ABK89557,,,U112,GreA (FTN_0665),,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,transcription elongation factor,,,,reduced virulence,,,,,,,,wild type,,no,NaCl,NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,29720697,PubMed,10.1038/s41598-018-25271-5,Sci Rep. 2018 May 2;8(1):6895,suzhang@cau.edu.cn,Deletion of F. novicida greA gene impaired its ability to invade and replicate within host cells.,G Cui 2018,2018,3 genes,Cui-2018-Transcription Elongation Factor GreA,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11355,PHI:8070,UniProt,A0Q850,GenBank,ABK90415,,,U112,ampD (FTN_1551),,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29720697,PubMed,10.1038/s41598-018-25271-5,Sci Rep. 2018 May 2;8(1):6895,suzhang@cau.edu.cn,Deletion of F. novicida greA gene impaired its ability to invade and replicate within host cells.,G Cui 2018,2018,3 genes,Cui-2018-Transcription Elongation Factor GreA,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11356,PHI:8071,UniProt,A0Q757,GenBank,ABK90072,,,U112,pepO (FTN_1186),,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,M13 family metallopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29720697,PubMed,10.1038/s41598-018-25271-5,Sci Rep. 2018 May 2;8(1):6895,suzhang@cau.edu.cn,Deletion of F. novicida greA gene impaired its ability to invade and replicate within host cells.,G Cui 2018,2018,3 genes,Cui-2018-Transcription Elongation Factor GreA,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11357,PHI:8072,UniProt,P0AC51,GenBank,BAE78048,,,K-12,zur,,,,,,,562,Escherichia coli,1206108,J96,pyelonephritis,primates,9606,Homo sapiens (related: human),T24 cell line,,,T-24 cell,zinc uptake regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,ZnCl2,ZnCl2: CHEBI:49976,,,,,gene deletion: partial; gene complementation,,,YVS,29695842,PubMed,10.1038/s41598-018-24964-1,Sci Rep. 2018 Apr 25;8(1):6535,cbalsalobre@ub.edu,ΔZur mutation triggered virulence-associated features such as hemoglobin release and disruption of epithelial cell adhesion. bladder epithelial cells,E Velasco 2018,2018,1 gene,Velasco-2018-A new role for Zinc limitation in,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11358,PHI:8073,,no data found,GenBank,ATV03510,,,O11,saeQ,,,,,,PHI:8073; PHI:8074,1280,Staphylococcus aureus,,NYU Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,kidney; heart,putative membrane protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28924032,PubMed,10.1128/JB.00476-17,J Bacteriol. 2017 Sep 18. pii: JB.00476-17,victor.torres@nyumc.org,"SNP C595T in Newman D2C abolished pathogenesis. The NYU Newman saeR allele restored cytotoxicity to an ΔsaeQRS mutant, whereas the saeQRS allele from Newman D2C provided no restoration of cytotoxicity.",W E Sause 2017,2017,3 genes,Sause-2017-Staphylococcus aureus strain Newman,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11359,PHI:8074,UniProt,Q2G2G2,GenBank,CAD89110,,,Newman,saeR,,,,,,PHI:8073; PHI:8075,1280,Staphylococcus aureus,,NYU Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,kidney; heart,response regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28924032,PubMed,10.1128/JB.00476-17,J Bacteriol. 2017 Sep 18. pii: JB.00476-17,victor.torres@nyumc.org,"SNP C595T in Newman D2C abolished pathogenesis. The NYU Newman saeR allele restored cytotoxicity to an ΔsaeQRS mutant, whereas the saeQRS allele from Newman D2C provided no restoration of cytotoxicity.",W E Sause 2017,2017,3 genes,Sause-2017-Staphylococcus aureus strain Newman,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11360,PHI:8075,UniProt,Q2G2U1,GenBank,CAD89111,,,Newman,saeS,,,,,,PHI:8074; PHI:8075,1280,Staphylococcus aureus,,NYU Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,kidney; heart,histidine kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28924032,PubMed,10.1128/JB.00476-17,J Bacteriol. 2017 Sep 18. pii: JB.00476-17,victor.torres@nyumc.org,"SNP C595T in Newman D2C abolished pathogenesis. The NYU Newman saeR allele restored cytotoxicity to an ΔsaeQRS mutant, whereas the saeQRS allele from Newman D2C provided no restoration of cytotoxicity.",W E Sause 2017,2017,3 genes,Sause-2017-Staphylococcus aureus strain Newman,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11361,PHI:8073,,no data found,GenBank,ATV03510,,,O11,saeQ,,SNP C595T,,,,PHI:8073; PHI:8074,1280,Staphylococcus aureus,,Newman D2C,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,kidney; heart,putative membrane protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28924032,PubMed,10.1128/JB.00476-17,J Bacteriol. 2017 Sep 18. pii: JB.00476-17,victor.torres@nyumc.org,"SNP C595T in Newman D2C abolished pathogenesis. The NYU Newman saeR allele restored cytotoxicity to an ΔsaeQRS mutant, whereas the saeQRS allele from Newman D2C provided no restoration of cytotoxicity.",W E Sause 2017,2017,3 genes,Sause-2017-Staphylococcus aureus strain Newman,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11362,PHI:8074,UniProt,Q2G2G2,GenBank,CAD89110,,,Newman,saeR,,SNP C595T,,,,PHI:8073; PHI:8075,1280,Staphylococcus aureus,,Newman D2C,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,kidney; heart,response regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28924032,PubMed,10.1128/JB.00476-17,J Bacteriol. 2017 Sep 18. pii: JB.00476-17,victor.torres@nyumc.org,"SNP C595T in Newman D2C abolished pathogenesis. The NYU Newman saeR allele restored cytotoxicity to an ΔsaeQRS mutant, whereas the saeQRS allele from Newman D2C provided no restoration of cytotoxicity.",W E Sause 2017,2017,3 genes,Sause-2017-Staphylococcus aureus strain Newman,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11363,PHI:8075,UniProt,Q2G2U1,GenBank,CAD89111,,,Newman,saeS,,SNP C595T,,,,PHI:8074; PHI:8075,1280,Staphylococcus aureus,,Newman D2C,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,kidney; heart,histidine kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28924032,PubMed,10.1128/JB.00476-17,J Bacteriol. 2017 Sep 18. pii: JB.00476-17,victor.torres@nyumc.org,"SNP C595T in Newman D2C abolished pathogenesis. The NYU Newman saeR allele restored cytotoxicity to an ΔsaeQRS mutant, whereas the saeQRS allele from Newman D2C provided no restoration of cytotoxicity.",W E Sause 2017,2017,3 genes,Sause-2017-Staphylococcus aureus strain Newman,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11364,PHI:8076,UniProt,A0A0H2ZP86,GenBank,ABJ54913,,,D39,rgg144 (SPD_0144),,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung; blood,transcriptional activator,,,sugar metabolism,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29686372,PubMed,10.1038/s41598-018-24910-1,Sci Rep. 2018 Apr 23;8(1):6369,hy3@le.ac.uk,"Rgg systems played a key role in colonization and virulence, as deletion mutants of these QS systems were attenuated in the mouse models of colonization and pneumonia.",X Zhi 2018,2018,2 genes,Zhi-2018-Rgg-Shp regulators are important for,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11365,PHI:8076,UniProt,A0A0H2ZP86,GenBank,ABJ54913,,,D39,rgg144 (SPD_0144),,,,,,PHI:8077,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung; blood,transcriptional activator,,,sugar metabolism,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29686372,PubMed,10.1038/s41598-018-24910-1,Sci Rep. 2018 Apr 23;8(1):6369,hy3@le.ac.uk,"Rgg systems played a key role in colonization and virulence, as deletion mutants of these QS systems were attenuated in the mouse models of colonization and pneumonia.",X Zhi 2018,2018,2 genes,Zhi-2018-Rgg-Shp regulators are important for,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11366,PHI:8077,UniProt,A0A0H2ZNB8,GenBank,ABJ54684,,,D39,rgg939 (SPD_0939),,,,,,PHI:8076,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung; blood,transcriptional activator,,,sugar metabolism,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29686372,PubMed,10.1038/s41598-018-24910-1,Sci Rep. 2018 Apr 23;8(1):6369,hy3@le.ac.uk,"Rgg systems played a key role in colonization and virulence, as deletion mutants of these QS systems were attenuated in the mouse models of colonization and pneumonia.",X Zhi 2018,2018,2 genes,Zhi-2018-Rgg-Shp regulators are important for,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11367,PHI:8078,UniProt,A0A177E2S2,Author,MG593564,,,z7,tsa1,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,thioredoxin peroxidase,,,,reduced virulence,,,,,,,,wild type,,no,"H2O2; t-BHP; cumene hydroperoxide; NaCl; SDS; Congo red; chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile); boscalid (2-chloro-N-(4'-chlorobiphenyl-2-yl) nicotinamide); mancozeb; captan","H2O2: CHEBI:16240; t-BHP: CAS:75-91-2; cumene hydroperoxide: CHEBI:78673; NaCl: CHEBI:267101; SDS: CHEBI:8984; Congo red: CHEBI:34653; chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile): CHEBI:3639; boscalid (2-chloro-N-(4'-chlorobiphenyl-2-yl) nicotinamide): CHEBI:81822; mancozeb: CHEBI:52492; captan: CHEBI:34608",,,,,gene deletion: full; gene complementation,,,YVS,29752269,PubMed,10.1128/AEM.00086-18,Appl Environ Microbiol. 2018 May 11. pii: AEM.00086-18,krchung@nchu.edu.tw,Deletion mutants showing growth inhibition by oxidants were defective for H2O2 detoxification and induced smaller lesions on citrus leaves.,H Ma 2018,2018,3 genes,Ma-2018-Thioredoxin and glutaredoxin systems r,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11368,PHI:8079,UniProt,A0A2U8ZU72,Author,MG593563,,,z7,trr1,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,thioredoxin reductase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,"H2O2; t-BHP; cumene hydroperoxide; NaCl; SDS; Congo red; chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile); boscalid (2-chloro-N-(4'-chlorobiphenyl-2-yl) nicotinamide); mancozeb; captan","H2O2: CHEBI:16240; t-BHP: CAS:75-91-2; cumene hydroperoxide: CHEBI:78673; NaCl: CHEBI:267101; SDS: CHEBI:8984; Congo red: CHEBI:34653; chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile): CHEBI:3639; boscalid (2-chloro-N-(4'-chlorobiphenyl-2-yl) nicotinamide): CHEBI:81822; mancozeb: CHEBI:52492; captan: CHEBI:34608",,,,,gene deletion: full; gene complementation,,,YVS,29752269,PubMed,10.1128/AEM.00086-18,Appl Environ Microbiol. 2018 May 11. pii: AEM.00086-18,krchung@nchu.edu.tw,Deletion mutants showing growth inhibition by oxidants were defective for H2O2 detoxification and induced smaller lesions on citrus leaves.,H Ma 2018,2018,3 genes,Ma-2018-Thioredoxin and glutaredoxin systems r,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11369,PHI:8080,UniProt,A0A2U8ZT98,Author,MG593559,,,z7,glr1,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,glutathione reductase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,"H2O2; t-BHP; cumene hydroperoxide; NaCl; SDS; Congo red; chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile); boscalid (2-chloro-N-(4'-chlorobiphenyl-2-yl) nicotinamide); mancozeb; captan","H2O2: CHEBI:16240; tert-butyl-hydroxyperoxide (t-BHP): CHEBI:64090; cumene hydroperoxide: CHEBI:78673; NaCl: CHEBI:267101; SDS: CHEBI:8984; Congo red: CHEBI:34653; chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile): CHEBI:3639; boscalid (2-chloro-N-(4'-chlorobiphenyl-2-yl) nicotinamide): CHEBI:81822; mancozeb: CHEBI:52492; captan: CHEBI:34608",,,,,gene deletion: full; gene complementation,,,YVS,29752269,PubMed,10.1128/AEM.00086-18,Appl Environ Microbiol. 2018 May 11. pii: AEM.00086-18,krchung@nchu.edu.tw,Deletion mutants showing growth inhibition by oxidants were defective for H2O2 detoxification and induced smaller lesions on citrus leaves.,H Ma 2018,2018,3 genes,Ma-2018-Thioredoxin and glutaredoxin systems r,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11370,PHI:8081,,no data found,GenBank,BAH65947,,,NTUH-K2044,PEG344,,,,,,,573,Klebsiella pneumoniae,,hvKP1,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung; spleen; kidney; blood,inner membrane metabolite transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28717029,PubMed,10.1128/IAI.00093-17,Infect Immun. 2017 Sep 20;85(10). pii: e00093-17,trusso@acsu.buffalo.edu,"PEG344 was required for full virulence of hvKP1 in an outbred CD1 mouse pulmonary challenge model, but not required for full virulence in a subcutaneous challenge model.",J Bulger 2017,2017,1 gene,Bulger-2017-The metabolite transporter PEG344,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11371,PHI:8082,UniProt,P0AG82,GenBank,AAC76751,,,K-12,pstS,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney,phosphate ABC transporter periplasmic binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28924030,PubMed,10.1128/JB.00168-17,J Bacteriol. 2017 Nov 14;199(24). pii: e00168-17,charles.dozois@iaf.inrs.ca,"In the pst mutant, inactivation of yaiC restored fim-dependent adhesion to bladder cells and virulence.",S Crepin 2017,2017,4 genes,Crepin-2017-Altered regulation of the Diguanyl,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11372,PHI:8083,UniProt,P0AGH8,GenBank,AAC76750,,,K-12,pstC,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney,phosphate ABC transporter permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28924030,PubMed,10.1128/JB.00168-17,J Bacteriol. 2017 Nov 14;199(24). pii: e00168-17,charles.dozois@iaf.inrs.ca,"In the pst mutant, inactivation of yaiC restored fim-dependent adhesion to bladder cells and virulence.",S Crepin 2017,2017,4 genes,Crepin-2017-Altered regulation of the Diguanyl,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11373,PHI:8084,UniProt,P07654,GenBank,AAC76749,,,K-12,pstA,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney,phosphate ABC transporter permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28924030,PubMed,10.1128/JB.00168-17,J Bacteriol. 2017 Nov 14;199(24). pii: e00168-17,charles.dozois@iaf.inrs.ca,"In the pst mutant, inactivation of yaiC restored fim-dependent adhesion to bladder cells and virulence.",S Crepin 2017,2017,4 genes,Crepin-2017-Altered regulation of the Diguanyl,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11374,PHI:8085,UniProt,P0AAP1,GenBank,AAC73488,,,K-12,yaiC,,,,,,PHI:8082; PHI:8083; PHI:8084,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney,diguanylate cyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28924030,PubMed,10.1128/JB.00168-17,J Bacteriol. 2017 Nov 14;199(24). pii: e00168-17,charles.dozois@iaf.inrs.ca,"In the pst mutant, inactivation of yaiC restored fim-dependent adhesion to bladder cells and virulence.",S Crepin 2017,2017,4 genes,Crepin-2017-Altered regulation of the Diguanyl,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11375,PHI:8082,UniProt,P0AG82,GenBank,AAC76751,,,K-12,pstS,,,,,,PHI:8085; PHI:8083; PHI:8084,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney,phosphate ABC transporter periplasmic binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28924030,PubMed,10.1128/JB.00168-17,J Bacteriol. 2017 Nov 14;199(24). pii: e00168-17,charles.dozois@iaf.inrs.ca,"In the pst mutant, inactivation of yaiC restored fim-dependent adhesion to bladder cells and virulence.",S Crepin 2017,2017,4 genes,Crepin-2017-Altered regulation of the Diguanyl,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11376,PHI:8083,UniProt,P0AGH8,GenBank,AAC76750,,,K-12,pstC,,,,,,PHI:8085; PHI:8082; PHI:8084,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney,phosphate ABC transporter permease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28924030,PubMed,10.1128/JB.00168-17,J Bacteriol. 2017 Nov 14;199(24). pii: e00168-17,charles.dozois@iaf.inrs.ca,"In the pst mutant, inactivation of yaiC restored fim-dependent adhesion to bladder cells and virulence.",S Crepin 2017,2017,4 genes,Crepin-2017-Altered regulation of the Diguanyl,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11377,PHI:8084,UniProt,P07654,GenBank,AAC76749,,,K-12,pstA,,,,,,PHI:8085; PHI:8082; PHI:8083,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney,phosphate ABC transporter permease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28924030,PubMed,10.1128/JB.00168-17,J Bacteriol. 2017 Nov 14;199(24). pii: e00168-17,charles.dozois@iaf.inrs.ca,"In the pst mutant, inactivation of yaiC restored fim-dependent adhesion to bladder cells and virulence.",S Crepin 2017,2017,4 genes,Crepin-2017-Altered regulation of the Diguanyl,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11378,PHI:8086,UniProt,Q9I1S4,GenBank,AE004645_13,,,PAO1,ExoY,,ExoY K81M,,,,,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29734720,PubMed,10.3390/toxins10050185,Toxins (Basel). 2018 May 4;10(5). pii: E185,schirmer.bastian@mh-hannover.de,"Infections with Pseudomonas aeruginosa mutants expressing either nucleotidyl cyclase-active or -inactive ExoY revealed differential cytokine secretion, increased prevalence of apoptosis, and a break of lung barrier integrity in mice infected with cyclase-active ExoY.",C Kloth 2018,2018,1 gene,Kloth-2018-The Role of Pseudomonas aeruginosa,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11379,PHI:8087,UniProt,O94103,Author,CE1179974_10589,,,,CgCdc42,,,,,,,474922,Colletotrichum gloeosporioides,,CFCC80308,anthracnose (poplar),eudicots,1217306,Populus x beijingensis (no common name found),,,,leaf,Rho GTPase,,,,reduced virulence,,yes,,yes,,aberrant,,reduced; aberrant,wild type,no,H2O2; chloral hydrate; calcofluor white (CFW); Congo red (CR),H2O2: CHEBI:16240; chloral hydrate: CHEBI:28142; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,29700579,PubMed,10.1007/s00294-018-0833-9,Curr Genet. 2018 Apr 26,chengmt@bjfu.edu.cn,"ROS scavenging assay indicated that the ΔCgCdc42 mutants maintained wild type pathogenicity in the absence of ROS despite having fewer appressoria than wild type, suggesting that the ΔCgCdc42 mutants were deficient in their tolerance of ROS.",X Wang 2018,2018,1 gene,Wang-2018-A Cdc42 homolog in Colletotrichum gl,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11380,PHI:8089,UniProt,C5MDS0,GenBank,EER32151,,,MNN4 (XP_002549525),MYA-3404,,,,,,,5482,Candida tropicalis,294747,ATCC MYA-3404,oral mucosa infection; genital tract infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,phosphomannosylation pathway,,,,reduced virulence,,,,,,,,wild type,,no,Congo red; calcofluor white; hygromycin B,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hygromycin B: CHEBI:16976,,,,,gene deletion: full; gene complementation,,,YVS,29718196,PubMed,10.1093/femsyr/foy053,FEMS Yeast Res. 2018 Apr 27,hmora@ugto.mx,"The C. tropicalis mnn4Δ did not show defects in the ability to stimulate cytokine production by human mononuclear cells but displayed virulence attenuation in an insect model of candidiasis. Also, the mnn4Δ null mutant strain was barely phagocytosed by human monocyte-derived macrophages.",M J Hernández-Chávez 2018,2018,1 gene,Hernandez-Chave-2018-Role of protein phosphoma,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11381,PHI:8090,UniProt,Q8ZKN5,GenBank,AAL22940,,,LT2; SGSC 1412; ATCC 700720,metB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,cystathionine gamma-synthase,,,methionine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11382,PHI:8091,UniProt,Q9L6N1,GenBank,AAL22809,,,LT2; SGSC 1412; ATCC 700720,metE,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase,,,methionine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11383,PHI:8092,UniProt,P37586,GenBank,AAL23012,,,LT2; SGSC 1412; ATCC 700720,metH,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,methionine synthase,,,methionine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11384,PHI:8091,UniProt,Q9L6N1,GenBank,AAL22809,,,LT2; SGSC 1412; ATCC 700720,metE,,,,,,PHI:8092,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase,,,methionine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11385,PHI:8092,UniProt,P37586,GenBank,AAL23012,,,LT2; SGSC 1412; ATCC 700720,metH,,,,,,PHI:8091,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,methionine synthase,,,methionine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11386,PHI:8093,UniProt,A0A0F6AX50,GenBank,ACY86822,,,14028S,metN,,,,,,PHI:8094; PHI:8095,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,methionine import ATP-binding protein,,,methionine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11387,PHI:8094,UniProt,Q8ZRN0,GenBank,AAL19209,,,LT2; SGSC 1412; ATCC 700720,metI,,,,,,PHI:8093; PHI:8095,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,D-methionine transport system permease protein,,,methionine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11388,PHI:8095,UniProt,Q8ZRN1,GenBank,AAL19208,,,LT2; SGSC 1412; ATCC 700720,metQ,,,,,,PHI:8094; PHI:8095,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,D-methionine-binding lipoprotein,,,methionine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11389,PHI:8093,UniProt,A0A0F6AX50,GenBank,ACY86822,,,14028S,metN,,,,,,PHI:8094; PHI:8095; PHI:8090,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,methionine import ATP-binding protein,,,methionine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11390,PHI:8094,UniProt,Q8ZRN0,GenBank,AAL19209,,,LT2; SGSC 1412; ATCC 700720,metI,,,,,,PHI:8093; PHI:8095; PHI:8090,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,D-methionine transport system permease protein,,,methionine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11391,PHI:8095,UniProt,Q8ZRN1,GenBank,AAL19208,,,LT2; SGSC 1412; ATCC 700720,metQ,,,,,,PHI:8093; PHI:8094; PHI:8090,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,D-methionine-binding lipoprotein,,,methionine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11392,PHI:8090,UniProt,Q8ZKN5,GenBank,AAL22940,,,LT2; SGSC 1412; ATCC 700720,metB,,,,,,PHI:8093; PHI:8094; PHI:8095,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,cystathionine gamma-synthase,,,methionine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11393,PHI:8093,UniProt,A0A0F6AX50,GenBank,ACY86822,,,14028S,metN,,,,,,PHI:8094; PHI:8095; PHI:8091; PHI:8092,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,methionine import ATP-binding protein,,,methionine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11394,PHI:8094,UniProt,Q8ZRN0,GenBank,AAL19209,,,LT2; SGSC 1412; ATCC 700720,metI,,,,,,PHI:8093; PHI:8095; PHI:8091; PHI:8092,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,D-methionine transport system permease protein,,,methionine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11395,PHI:8095,UniProt,Q8ZRN1,GenBank,AAL19208,,,LT2; SGSC 1412; ATCC 700720,metQ,,,,,,PHI:8093; PHI:8094; PHI:8091; PHI:8092,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,D-methionine-binding lipoprotein,,,methionine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11396,PHI:8091,UniProt,Q9L6N1,GenBank,AAL22809,,,LT2; SGSC 1412; ATCC 700720,metE,,,,,,PHI:8093; PHI:8094; PHI:8095; PHI:8092,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase,,,methionine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11397,PHI:8092,UniProt,P37586,GenBank,AAL23012,,,LT2; SGSC 1412; ATCC 700720,metH,,,,,,PHI:8093; PHI:8094; PHI:8095; PHI:8091,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,methionine synthase,,,methionine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,29720401,PubMed,10.1074/jbc.RA118.002592,J Biol Chem. 2018 May 2. pii: jbc.RA118.002592,nancyw@unimelb.edu.au,ΔMetNIQΔmetB and ΔmetNIQΔmetEH are attenuated in mice regardless of the route of infection.,A U Husna 2018,2018,6 genes,Husna-2018-Methionine biosynthesis and transpo,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11398,PHI:8096,UniProt,A0A2P4G5R7,GenBank,POY79830,,,R15300,hopAB1,,,,,,,317,Pseudomonas syringae,,pv. morsprunorum strain R1-5244,bacterial canker,eudicots,42229,Prunus avium (related: Sweet cherry),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: ectopic expression of transconjugants,,,YVS,29726587,PubMed,10.1111/nph.15182,New Phytol. 2018 May 4,richard.harrison@emr.ac.uk,Ectopic expression of hopAB and hopC1 triggered the hypersensitive reaction in cherry leaves.,M T Hulin 2018,2018,4 genes,Hulin-2018-Comparative genomics of Pseudomonas,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11399,PHI:8097,UniProt,F3DUQ1,GenBank,EGH09548,,,M302280,hopAB2,,,,,,,317,Pseudomonas syringae,,pv. morsprunorum strain R1-5244,bacterial canker,eudicots,42229,Prunus avium (related: Sweet cherry),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: ectopic expression of transconjugants,,,YVS,29726587,PubMed,10.1111/nph.15182,New Phytol. 2018 May 4,richard.harrison@emr.ac.uk,Ectopic expression of hopAB and hopC1 triggered the hypersensitive reaction in cherry leaves.,M T Hulin 2018,2018,4 genes,Hulin-2018-Comparative genomics of Pseudomonas,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11400,PHI:8098,UniProt,Q2QCI9,GenBank,ABA00713,,,JL1065,hopAB3,,,,,,,317,Pseudomonas syringae,,pv. morsprunorum strain R1-5244,bacterial canker,eudicots,42229,Prunus avium (related: Sweet cherry),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: ectopic expression of transconjugants,,,YVS,29726587,PubMed,10.1111/nph.15182,New Phytol. 2018 May 4,richard.harrison@emr.ac.uk,Ectopic expression of hopAB and hopC1 triggered the hypersensitive reaction in cherry leaves.,M T Hulin 2018,2018,4 genes,Hulin-2018-Comparative genomics of Pseudomonas,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11401,PHI:8099,UniProt,Q88A08,GenBank,AAO54131,,,DC3000,hopC1,,,,,,,317,Pseudomonas syringae,,pv. morsprunorum strain R1-5244,bacterial canker,eudicots,42229,Prunus avium (related: Sweet cherry),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: ectopic expression of transconjugants,,,YVS,29726587,PubMed,10.1111/nph.15182,New Phytol. 2018 May 4,richard.harrison@emr.ac.uk,Ectopic expression of hopAB and hopC1 triggered the hypersensitive reaction in cherry leaves.,M T Hulin 2018,2018,4 genes,Hulin-2018-Comparative genomics of Pseudomonas,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11402,PHI:8100,UniProt,J7M3X4,GenBank,BAM30714,,,M1 476,rocA,chromosome 1,,,,,,1314,Streptococcus pyogenes,,MGAS2221,infection,primates,9606,Homo sapiens (related: human),,,,blood,sensory transduction protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28808155,PubMed,10.1128/IAI.00274-17,Infect Immun. 2017 Oct 18;85(11). pii: e00274-17,psumby@medicine.nevada.edu,RocA negatively regulated survival in human blood and production of the antiphagocytic capsule.,I Jain 2017,2017,1 gene,Jain-2017-RocA is an accessory protein to the,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11403,PHI:8101,UniProt,A0A384K6E3,GenBank,XP_001546896,,,B05.10,Bcpck1,chromosome 16,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,phosphoenolpyruvate carboxykinase,,,gluconeogenesis,reduced virulence,,yes,yes,,,reduced; aberrant,,wild type,reduced,no,NaCl; KCl; H2O2; sodium dodecyl sulfate (SDS); Congo red,NaCl: CHEBI:267101; KCl: CHEBI:32588; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29614212,PubMed,10.1111/1462-2920.14112,Environ Microbiol. 2018 May;20(5):1794-1814,qmqin@jlu.edu.cn,The wild-type and ΔBcpck1 conidia germinated similarly in the presence of glucose (higher concentration) as the sole carbon source.,J K Liu 2018,2018,1 gene,Liu-2018-The key gluconeogenic gene PCK1 is cr,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11404,PHI:8101,UniProt,A0A384K6E3,GenBank,XP_001546896,,,B05.10,Bcpck1,chromosome 16,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,phosphoenolpyruvate carboxykinase,,,gluconeogenesis,reduced virulence,,yes,yes,,,reduced; aberrant,,wild type,reduced,no,NaCl; KCl; H2O2; sodium dodecyl sulfate (SDS); Congo red,NaCl: CHEBI:267101; KCl: CHEBI:32588; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29614212,PubMed,10.1111/1462-2920.14112,Environ Microbiol. 2018 May;20(5):1794-1814,qmqin@jlu.edu.cn,The wild-type and ΔBcpck1 conidia germinated similarly in the presence of glucose (higher concentration) as the sole carbon source.,J K Liu 2018,2018,1 gene,Liu-2018-The key gluconeogenic gene PCK1 is cr,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11405,PHI:8101,UniProt,A0A384K6E3,GenBank,XP_001546896,,,B05.10,Bcpck1,chromosome 16,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,phosphoenolpyruvate carboxykinase,,,gluconeogenesis,reduced virulence,,yes,yes,,,reduced; aberrant,,wild type,reduced,no,NaCl; KCl; H2O2; sodium dodecyl sulfate (SDS); Congo red,NaCl: CHEBI:267101; KCl: CHEBI:32588; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29614212,PubMed,10.1111/1462-2920.14112,Environ Microbiol. 2018 May;20(5):1794-1814,qmqin@jlu.edu.cn,The wild-type and ΔBcpck1 conidia germinated similarly in the presence of glucose (higher concentration) as the sole carbon source.,J K Liu 2018,2018,1 gene,Liu-2018-The key gluconeogenic gene PCK1 is cr,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11406,PHI:8102,UniProt,A0A0H3JSQ8,GenBank,BAB58226,,,Mu50,sigB,,Q225P,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; skin,"stress response regulator, RNA polymerase sigma factor",,,biosynthesis of golden carotenoid pigment (staphyloxanthin),unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene mutation,,,YVS,29691368,PubMed,10.1038/s41426-018-0078-1,Emerg Microbes Infect. 2018 Apr 25;7(1):72,yangyi19871230@126.com,SigB(Q225P) mutation in S. aureus impaired the staphyloxanthin production but retained bacterial virulence and promoted biofilm formation.,H Liu 2018,2018,1 gene,Liu-2018-A novel SigB(Q225P) mutation in Staph,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11407,PHI:8103,,no data found,Author,OG1RF_RS11640,,,,cstr,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,reactive sulfur species (RSS)-sensing sulfurtransferase repressor,,,,reduced virulence,,,,,,,,,,no,sodium sulfide; angeli's salt,sodium sulfide: CHEBI:76208; Angeli's salt: CAS:13826-64-7,,,,,gene deletion: full,,,YVS,29712426,PubMed,10.1021/acschembio.8b00230,ACS Chem Biol. 2018 May 17,giedroc@indiana.edu,A ΔcstR strain exhibited deficiency in catheter colonization in a catheter-associated urinary tract infection (CAUTI) mouse model suggesting sulfide regulation and homeostasis was critical for pathogenicity.,J Shen 2018,2018,1 gene,Shen-2018-Hydrogen sulfide sensing through rea,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11408,PHI:8104,UniProt,A0A1D8PMR6,GenBank,AOW29418,,,SC5314,zrt1,chromosome 4,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,putative zinc transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29727465,PubMed,10.1371/journal.ppat.1007013,PLoS Pathog. 2018 May 4;14(5):e1007013,Duncan.Wilson@abdn.ac.uk,Host gene alteration data available for calprotectin. Zrt1 and Zrt2 were dispensable for initial kidney colonisation (day one post-infection) and that Zrt2 was important for systemic candidiasis at later stages.,A C Crawford 2018,2018,3 genes,Crawford-2018-Biphasic zinc compartmentalisati,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11409,PHI:8105,UniProt,A0A1D8PGN5,GenBank,AOW27297,,,SC5314,zrt2,chromosome 2,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,putative zinc transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29727465,PubMed,10.1371/journal.ppat.1007013,PLoS Pathog. 2018 May 4;14(5):e1007013,Duncan.Wilson@abdn.ac.uk,Host gene alteration data available for calprotectin. Zrt1 and Zrt2 were dispensable for initial kidney colonisation (day one post-infection) and that Zrt2 was important for systemic candidiasis at later stages.,A C Crawford 2018,2018,3 genes,Crawford-2018-Biphasic zinc compartmentalisati,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11410,PHI:8106,UniProt,A0A1D8PGL8,GenBank,AOW27260,,,SC5314,zrc1 (orf19.1536),chromosome 2,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,putative zinc transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29727465,PubMed,10.1371/journal.ppat.1007013,PLoS Pathog. 2018 May 4;14(5):e1007013,Duncan.Wilson@abdn.ac.uk,Host gene alteration data available for calprotectin. Zrt1 and Zrt2 were dispensable for initial kidney colonisation (day one post-infection) and that Zrt2 was important for systemic candidiasis at later stages.,A C Crawford 2018,2018,3 genes,Crawford-2018-Biphasic zinc compartmentalisati,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11411,PHI:8106,UniProt,A0A1D8PGL8,GenBank,AOW27260,,,SC5314,zrc1 (orf19.1536),chromosome 2,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver,putative zinc transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29727465,PubMed,10.1371/journal.ppat.1007013,PLoS Pathog. 2018 May 4;14(5):e1007013,Duncan.Wilson@abdn.ac.uk,Host gene alteration data available for calprotectin. Zrt1 and Zrt2 were dispensable for initial kidney colonisation (day one post-infection) and that Zrt2 was important for systemic candidiasis at later stages.,A C Crawford 2018,2018,3 genes,Crawford-2018-Biphasic zinc compartmentalisati,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11412,PHI:8107,UniProt,P08191,GenBank,CAA29156,,,,fimH,,,,,,,562,Escherichia coli,,CP9,urinary tract infection; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; lung; liver,type 1 pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28808163,PubMed,10.1128/IAI.00581-17,Infect Immun. 2017 Oct 18;85(11). pii: e00581-17,maresso@bcm.edu,"In a murine model of chemotherapy-induced translocation, ExPEC lacking fimH colonized at levels comparable to that of the wild type but demonstrated a statistically significant reduction in translocation to the kidneys, spleen and lungs indicating that FimH is important for ExPEC translocation.",N M Poole 2017,2017,1 gene,Poole-2017-A Role for FimH in Extraintestinal,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11413,PHI:8108,UniProt,Q0UIQ2,GenBank,EAT84638,,,SN15,PnCon7,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Corack,,,leaf,C2H2 zinc finger transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29722915,PubMed,10.1111/mmi.13968,Mol Microbiol. 2018 May 3,peter.solomon@anu.edu.au,Pathogenicity assays using PnCon7-silenced isolates revealed that the transcription factor was required for Tox3-mediated disease.,S Y Lin 2018,2018,1 gene,Lin-2018-The global regulator of pathogenesis,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11414,PHI:8108,UniProt,Q0UIQ2,GenBank,EAT84638,,,SN15,PnCon7,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Axe,,,leaf,C2H2 zinc finger transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,29722915,PubMed,10.1111/mmi.13968,Mol Microbiol. 2018 May 3,peter.solomon@anu.edu.au,Pathogenicity assays using PnCon7-silenced isolates revealed that the transcription factor was required for Tox3-mediated disease.,S Y Lin 2018,2018,1 gene,Lin-2018-The global regulator of pathogenesis,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11415,PHI:8109,UniProt,G4MQX3,GenBank,EHA58204,,,70-15,MoMip11 (MGG_04719),chromosome 1,,,MoRgs7; MoMagA; MoPdeH,UniProt: G4NF12; GenBank: EHA49531; UniProt: G4MW64; GenBank: EHA55024; UniProt: G4MP01; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,guanine nucleotide-binding protein subunit beta-like protein,,,,reduced virulence,yes,no,yes,,,reduced,reduced,reduced; aberrant,,no,fludioxonil; H2O2; dithiothreitol (DTT),fludioxonil: CHEBI:81763; H2O2: CHEBI:16240; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,29727050,PubMed,10.1111/1462-2920.14102,Environ Microbiol. 2018 May 4,zhgzhang@njau.edu.cn,"MoMip11 was found to be important for growth, asexual and sexual development.",Z Yin 2018,2018,2 genes,"Yin-2018-MoMip11, a MoRgs7-interacting protein",BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11416,PHI:8110,UniProt,G4NF12,GenBank,EHA49531,,,70-15,MoRgs7 (MGG_11693),chromosome 5,,,MoMip11,UniProt: G4MQX3; GenBank: EHA58204,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29727050,PubMed,10.1111/1462-2920.14102,Environ Microbiol. 2018 May 4,zhgzhang@njau.edu.cn,"MoMip11 was found to be important for growth, asexual and sexual development.",Z Yin 2018,2018,2 genes,"Yin-2018-MoMip11, a MoRgs7-interacting protein",BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11417,PHI:8110,UniProt,G4NF12,GenBank,EHA49531,,,70-15,MoRgs7 (MGG_11693),chromosome 5,MoRgs7ΔTM (seven-transmembrane domain),,MoMip11,UniProt: G4MQX3; GenBank: EHA58204,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29727050,PubMed,10.1111/1462-2920.14102,Environ Microbiol. 2018 May 4,zhgzhang@njau.edu.cn,"MoMip11 was found to be important for growth, asexual and sexual development.",Z Yin 2018,2018,2 genes,"Yin-2018-MoMip11, a MoRgs7-interacting protein",BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11418,PHI:8111,UniProt,P15320,GenBank,AAA50323,,,W1436,shlA (SCBI_3479),,,,,,,615,Serratia marcescens,,SCBI,opportunistic infection,moths,7130,Manduca sexta (related: tobacco hornworm),,,,larva,hemolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28784817,PubMed,10.1128/JB.00333-17,J Bacteriol. 2017 Oct 3;199(21). pii: e00333-17,louis.tisa@unh.edu,"Inactivation of the hemolysin gene in Serratia sp. SCBI resulted in loss of hemolytic acitvity, significantly increased motility and increased antimicrobial activity.",L M Petersen 2017,2017,2 genes,Petersen-2017-Inactivation of the major hemoly,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11419,PHI:8112,,no data found,,,,,,swrA (SCBI_4162),,transposon insertion at the bp 8700 position of swrA,,,,,615,Serratia marcescens,,SCBI,opportunistic infection,moths,7130,Manduca sexta (related: tobacco hornworm),,,,larva,nonribosomal peptide synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28784817,PubMed,10.1128/JB.00333-17,J Bacteriol. 2017 Oct 3;199(21). pii: e00333-17,louis.tisa@unh.edu,"Mutation of the swrA gene in Serratia sp. SCBI resulted in highly varied antibiotic activity, motility, virulence, and hemolysis phenotypes that were dependent on the siteof disruption within this 17.75-kb gene.",L M Petersen 2017,2017,2 genes,Petersen-2017-Inactivation of the major hemoly,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11420,PHI:8112,,no data found,,,,,,swrA (SCBI_4162),,transposon insertion at the bp 10242 position of swrA,,,,,615,Serratia marcescens,,SCBI,opportunistic infection,moths,7130,Manduca sexta (related: tobacco hornworm),,,,larva,nonribosomal peptide synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28784817,PubMed,10.1128/JB.00333-17,J Bacteriol. 2017 Oct 3;199(21). pii: e00333-17,louis.tisa@unh.edu,"Mutation of the swrA gene in Serratia sp. SCBI resulted in highly varied antibiotic activity, motility, virulence, and hemolysis phenotypes that were dependent on the siteof disruption within this 17.75-kb gene.",L M Petersen 2017,2017,2 genes,Petersen-2017-Inactivation of the major hemoly,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11421,PHI:8112,,no data found,,,,,,swrA (SCBI_4162),,transposon insertion at the bp 16198 position of swrA,,,,,615,Serratia marcescens,,SCBI,opportunistic infection,moths,7130,Manduca sexta (related: tobacco hornworm),,,,larva,nonribosomal peptide synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28784817,PubMed,10.1128/JB.00333-17,J Bacteriol. 2017 Oct 3;199(21). pii: e00333-17,louis.tisa@unh.edu,"Mutation of the swrA gene in Serratia sp. SCBI resulted in highly varied antibiotic activity, motility, virulence, and hemolysis phenotypes that were dependent on the siteof disruption within this 17.75-kb gene.",L M Petersen 2017,2017,2 genes,Petersen-2017-Inactivation of the major hemoly,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11422,PHI:8113,UniProt,B1I9H6,GenBank,ACA35890,,,Hungary19A-6,ritR,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,10090,Mus musculus (related: house mouse),,,,nasopharynx,two-component-like orphan response regulator,,,,reduced virulence,,,,,,,,,,no,H2O2; dithiothreitol (DTT); diamide,H2O2: CHEBI:16240; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,29750817,PubMed,10.1371/journal.ppat.1007052,PLoS Pathog. 2018 May 11;14(5):e1007052,aulijasz@luc.edu,RitR Cys128 oxidation was required for optimal colonization of the nasopharynx in D39 serotype 2.,D G Glanville 2018,2018,1 gene,Glanville-2018-RitR is an archetype for a nove,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11423,PHI:8113,UniProt,B1I9H6,GenBank,ACA35890,,,Hungary19A-6,ritR,,C128A,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,10090,Mus musculus (related: house mouse),,,,nasopharynx,two-component-like orphan response regulator,,,,reduced virulence,,,,,,,,,,no,H2O2; dithiothreitol (DTT); diamide,H2O2: CHEBI:16240; dithiothreitol (DTT): CHEBI:42170,,,,,gene mutation; gene complementation,,,YVS,29750817,PubMed,10.1371/journal.ppat.1007052,PLoS Pathog. 2018 May 11;14(5):e1007052,aulijasz@luc.edu,RitR Cys128 oxidation was required for optimal colonization of the nasopharynx in D39 serotype 2.,D G Glanville 2018,2018,1 gene,Glanville-2018-RitR is an archetype for a nove,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11424,PHI:8113,UniProt,B1I9H6,GenBank,ACA35890,,,Hungary19A-6,ritR,,C128S,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,10090,Mus musculus (related: house mouse),,,,nasopharynx,two-component-like orphan response regulator,,,,reduced virulence,,,,,,,,,,no,H2O2; dithiothreitol (DTT); diamide,H2O2: CHEBI:16240; dithiothreitol (DTT): CHEBI:42170,,,,,gene mutation; gene complementation,,,YVS,29750817,PubMed,10.1371/journal.ppat.1007052,PLoS Pathog. 2018 May 11;14(5):e1007052,aulijasz@luc.edu,RitR Cys128 oxidation was required for optimal colonization of the nasopharynx in D39 serotype 2.,D G Glanville 2018,2018,1 gene,Glanville-2018-RitR is an archetype for a nove,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11425,PHI:8113,UniProt,B1I9H6,GenBank,ACA35890,,,Hungary19A-6,ritR,,C128D,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,otitis media,rodents,10090,Mus musculus (related: house mouse),,,,nasopharynx,two-component-like orphan response regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; dithiothreitol (DTT); diamide,H2O2: CHEBI:16240; dithiothreitol (DTT): CHEBI:42170,,,,,gene mutation; gene complementation,,,YVS,29750817,PubMed,10.1371/journal.ppat.1007052,PLoS Pathog. 2018 May 11;14(5):e1007052,aulijasz@luc.edu,RitR Cys128 oxidation was required for optimal colonization of the nasopharynx in D39 serotype 2.,D G Glanville 2018,2018,1 gene,Glanville-2018-RitR is an archetype for a nove,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 11426,PHI:8114,UniProt,A0A384JZY5,GenBank,XP_001553895,,,B05.10,BcKMO,chromosome 12,,,,,,40559,Botrytis cinerea,,BC22,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,kynurenine 3-monooxygenase,,,kynurenine pathway,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,NaCl; KCl; fluconazole; Congo red; menadione; H2O2; SQ22536; U0126,"NaCl: CHEBI:26710; KCl: CHEBI:32588; fluconazole: CHEBI:46081, CAS:86386-73-4; Congo red: CHEBI:34653; menadione: CHEBI:28869; H2O2: CHEBI:16240; SQ22536: CHEBI:90232; U0126: CHEBI:90693",,,,,altered gene expression / gene regulation: silencing: gene complementation,,,YVS,29867912,PubMed,10.3389/fmicb.2018.01039,Front Microbiol. 2018 May 18;9:1039,dongjingao@126.com,"BcKMO positively regulated growth and development, but negatively regulated pathogenicity of B. cinerea.",K Zhang 2018,2018,1 gene,Zhang-2018-The Kynurenine 3-Monooxygenase Enco,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11427,PHI:8114,UniProt,A0A384JZY5,GenBank,XP_001553895,,,B05.10,BcKMO,chromosome 12,,,,,,40559,Botrytis cinerea,,BC22,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,kynurenine 3-monooxygenase,,,kynurenine pathway,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,NaCl; KCl; fluconazole; Congo red; menadione; H2O2; SQ22536; U0126,"NaCl: CHEBI:26710; KCl: CHEBI:32588; fluconazole: CHEBI:46081, CAS:86386-73-4; Congo red: CHEBI:34653; menadione: CHEBI:28869; H2O2: CHEBI:16240; SQ22536: CHEBI:90232; U0126: CHEBI:90693",,,,,altered gene expression / gene regulation: silencing: gene complementation,,,YVS,29867912,PubMed,10.3389/fmicb.2018.01039,Front Microbiol. 2018 May 18;9:1039,dongjingao@126.com,"BcKMO positively regulated growth and development, but negatively regulated pathogenicity of B. cinerea.",K Zhang 2018,2018,1 gene,Zhang-2018-The Kynurenine 3-Monooxygenase Enco,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11428,PHI:8115,UniProt,Q8VUN9,GenBank,BAB83969,,,NCTC10234,sntA,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),Kunming,,,blood; brain; lung,"surface exposed protein, bifunctional 2′,3′-cyclic nucleotide 2′-phosphodiesterase/3′-nucleotidase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29868022,PubMed,10.3389/fimmu.2018.01063,Front Immunol. 2018 May 16;9:1063,rzhou@mail.hzau.edu.cn,Snta inhibited the c3 deposition and MAC formation on S. suis.,S Deng 2018,2018,1 gene,Deng-2018-The Surface-Exposed Protein SntA Con,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11429,PHI:8116,UniProt,B8MZ49,GenBank,EED57641,,,NRRL3357,pbsB (AFLA_083380),,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,MAP kinase kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol,sorbitol: CHEBI:30911,,,,,gene deletion: full,,,YVS,29868518,PubMed,10.3389/fcimb.2018.00162,Front Cell Infect Microbiol. 2018 May 17;8:162,ZH_Zhuang@fafu.edu.cn,"Mycelia growth, conidiation, and the formation of sclerotia in ΔpbsB mutant were significantly suppressed, and up-regulated in OE strian compared to wild-type strain.",J Yuan 2018,2018,1 gene,"Yuan-2018-PbsB Regulates Morphogenesis, Aflato",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11430,PHI:8116,UniProt,B8MZ49,GenBank,EED57641,,,NRRL3357,pbsB (AFLA_083380),,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,MAP kinase kinase,,,,increased virulence (hypervirulence),,,,,,increased,,increased,,no,sorbitol,sorbitol: CHEBI:30911,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29868518,PubMed,10.3389/fcimb.2018.00162,Front Cell Infect Microbiol. 2018 May 17;8:162,ZH_Zhuang@fafu.edu.cn,"Mycelia growth, conidiation, and the formation of sclerotia in ΔpbsB mutant were significantly suppressed, and up-regulated in OE strian compared to wild-type strain.",J Yuan 2018,2018,1 gene,"Yuan-2018-PbsB Regulates Morphogenesis, Aflato",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11431,PHI:8116,UniProt,B8MZ49,GenBank,EED57641,,,NRRL3357,pbsB (AFLA_083380),,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,cotyledon,MAP kinase kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol,sorbitol: CHEBI:30911,,,,,gene deletion: full,,,YVS,29868518,PubMed,10.3389/fcimb.2018.00162,Front Cell Infect Microbiol. 2018 May 17;8:162,ZH_Zhuang@fafu.edu.cn,"Mycelia growth, conidiation, and the formation of sclerotia in ΔpbsB mutant were significantly suppressed, and up-regulated in OE strian compared to wild-type strain.",J Yuan 2018,2018,1 gene,"Yuan-2018-PbsB Regulates Morphogenesis, Aflato",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11432,PHI:8116,UniProt,B8MZ49,GenBank,EED57641,,,NRRL3357,pbsB (AFLA_083380),,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,cotyledon,MAP kinase kinase,,,,increased virulence (hypervirulence),,,,,,increased,,increased,,no,sorbitol,sorbitol: CHEBI:30911,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29868518,PubMed,10.3389/fcimb.2018.00162,Front Cell Infect Microbiol. 2018 May 17;8:162,ZH_Zhuang@fafu.edu.cn,"Mycelia growth, conidiation, and the formation of sclerotia in ΔpbsB mutant were significantly suppressed, and up-regulated in OE strian compared to wild-type strain.",J Yuan 2018,2018,1 gene,"Yuan-2018-PbsB Regulates Morphogenesis, Aflato",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11433,PHI:8117,UniProt,Q18CX3,GenBank,CAJ67055,,,630,csra (CD630_02340),,,,,,,1496,Clostridioides difficile,,630Δerm,pseudomembranous colitis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,HT-29 cell,carbon storage regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29859293,PubMed,10.1016/j.micpath.2018.05.052,Microb Pathog. 2018 May 30;121:303-309,jufwang@scut.edu.cn,Overexpression of csrA in C. difficile displayed increased adhesion to Caco-2 cells. Epithelial colorectal adenocarcinoma cells,H Gu 2018,2018,1 gene,Gu-2018-Carbon storage regulator CsrA plays im,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11434,PHI:8117,UniProt,Q18CX3,GenBank,CAJ67055,,,630,csra (CD630_02340),,,,,,,1496,Clostridioides difficile,,630Δerm,pseudomembranous colitis,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,renal epithelial cell,carbon storage regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29859293,PubMed,10.1016/j.micpath.2018.05.052,Microb Pathog. 2018 May 30;121:303-309,jufwang@scut.edu.cn,Overexpression of csrA in C. difficile displayed increased adhesion to Caco-2 cells.,H Gu 2018,2018,1 gene,Gu-2018-Carbon storage regulator CsrA plays im,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11435,PHI:8118,UniProt,A0A0F7PWS5,GenBank,AKI05473,,,BCC 2660,pks14,,,,,,,176275,Beauveria bassiana,,BCC 2660,white muscardine,moths,7107,Spodoptera exigua (related: beet armyworm),,,,larva,reducing clade IIb polyketide synthase,,,,reduced virulence,,,,,,,,wild type,wild type,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene disruption,,,YVS,29790944,PubMed,10.1093/femsle/fny131,FEMS Microbiol Lett. 2018 May 22,alongkorn@biotec.or.th,The Δpks14 hyphal body number was reduced compared to the wild type by 33 to 37% and mycosis caused by Δpks14 mutants was noticeably decreased as compared to the B. bassiana wild type.,C Srisuksam 2018,2018,1 gene,Srisuksam-2018-The reducing clade IIb polyketi,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11436,PHI:8119,UniProt,M1VUY5,GenBank,CCE28582,,,20.1,log (cpur_02269)),,,,,,,5111,Claviceps purpurea,1111077,20.1,ergot,monocots,4550,Secale cereale (related: rye),cv. Lo37-PxLo55-N,,,floret,cytokinin-specific phosphoribohydrolase,,,cytokinin biosynthesis,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,29850931,PubMed,10.1007/s00294-018-0847-3,Curr Genet. 2018 May 30,petr.galuszka@upol.cz,Host gene alteration data available for ZmCKX1 (heterologous overexpression of cytokinin-degrading enzyme from maize).,S Kind 2018,2018,2 genes,Kind-2018-Manipulation of cytokinin level in t,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11437,PHI:8120,UniProt,M1WES1,GenBank,CCE30329,,,20.1,ipt-log (cpur_04177),,,,,,,5111,Claviceps purpurea,1111077,20.1,ergot,monocots,4550,Secale cereale (related: rye),cv. Lo37-PxLo55-N,,,floret,bifunctional cytokinin de novo synthesis enzyme having isopentenyl transferase activity and cytokinin-specific phosphoribohydrolase activity,,,cytokinin biosynthesis,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,29850931,PubMed,10.1007/s00294-018-0847-3,Curr Genet. 2018 May 30,petr.galuszka@upol.cz,Host gene alteration data available for ZmCKX1 (heterologous overexpression of cytokinin-degrading enzyme from maize).,S Kind 2018,2018,2 genes,Kind-2018-Manipulation of cytokinin level in t,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11438,PHI:8119,UniProt,M1VUY5,GenBank,CCE28582,,,20.1,log (cpur_02269)),,,,,,PHI:8120,5111,Claviceps purpurea,1111077,20.1,ergot,monocots,4550,Secale cereale (related: rye),cv. Lo37-PxLo55-N,,,floret,cytokinin-specific phosphoribohydrolase,,,cytokinin biosynthesis,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,29850931,PubMed,10.1007/s00294-018-0847-3,Curr Genet. 2018 May 30,petr.galuszka@upol.cz,Host gene alteration data available for ZmCKX1 (heterologous overexpression of cytokinin-degrading enzyme from maize).,S Kind 2018,2018,2 genes,Kind-2018-Manipulation of cytokinin level in t,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11439,PHI:8120,UniProt,M1WES1,GenBank,CCE30329,,,20.1,ipt-log (cpur_04177),,,,,,PHI:8119,5111,Claviceps purpurea,1111077,20.1,ergot,monocots,4550,Secale cereale (related: rye),cv. Lo37-PxLo55-N,,,floret,bifunctional cytokinin de novo synthesis enzyme having isopentenyl transferase activity and cytokinin-specific phosphoribohydrolase activity,,,cytokinin biosynthesis,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,29850931,PubMed,10.1007/s00294-018-0847-3,Curr Genet. 2018 May 30,petr.galuszka@upol.cz,"Host gene alteration data available for cytokinin-degrading enzyme, ZmCKX1 (heterologous overexpression of cytokinin-degrading enzyme from maize). Zmckx1 overexpressing C. purpurea strains showed strong CKX activity and drastically reduced CK levels with impaired virulence.",S Kind 2018,2018,2 genes,Kind-2018-Manipulation of cytokinin level in t,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11440,PHI:8121,UniProt,A0A1D8PI19,GenBank,AOW27808,,,SC5314,CaPHM7,chromosome 2,,,,,,5476,Candida albicans,,CAI4,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,uncharacterized protein,,,,reduced virulence,,,,yes,,reduced,,reduced,,no,SDS; ketoconazole; rapamycin; zinc chloride,"SDS: CHEBI:8984; ketoconazole: CHEBI:47519, CAS:65277-42-1; rapamycin: CHEBI:9168; l,  zinc chloride: CHEBI:49976",,,,,gene deletion: full; gene complementation,,,YVS,29866033,PubMed,10.1186/s12866-018-1193-9,BMC Microbiol. 2018 Jun 4;18(1):49,linghuojiang@sdut.edu.cn,"Deletion of CaPHM7 led to a filamentation defect, reduced colony growth and attenuated virulence in the mouse model of systemic infection.",L Jiang 2018,2018,1 gene,Jiang-2018-Functions of CaPhm7 in the regulati,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11441,PHI:8122,UniProt,Q59VG6,GenBank,AOW26151,,,SC5314,erg3,chromosome 1,,,,,,5476,Candida albicans,,GP1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,"sterol Δ5,6-desaturase",,,,reduced virulence,,,,,,,,,,no,SDS; NaCl; CaCl2; fluconazole; voriconazole; itraconazole; ketoconazole,"SDS: CHEBI:8984; NaCl: CHEBI:26710; CaCl2: CHEBI:3312; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; ketoconazole: CHEBI:47519, CAS:65277-42-1",,,,,gene deletion: full; gene complementation,,,YVS,29789366,PubMed,10.1128/mBio.00225-18,MBio. 2018 May 22;9(3). pii: e00225-18,gpalmer5@uthsc.edu,"C. albicans erg3Δ/Δ mutant was unable to cause lethality in the disseminated model, it induced pathology in a mouse model of vaginal infection and the erg3Δ/Δ mutant was also more resistant to fluconazole treatment than the wild type in both models of infection.",A Luna-Tapia 2018,2018,1 gene,Luna-Tapia-2018-Loss of Upc2p-Inducible ERG3 T,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11442,PHI:8122,UniProt,Q59VG6,GenBank,AOW26151,,,SC5314,erg3,chromosome 1,,,,,,5476,Candida albicans,,GP1,vaginal candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,vagina,"sterol Δ5,6-desaturase",,,,unaffected pathogenicity,,,,,,,,,,no,SDS; NaCl; CaCl2; fluconazole; voriconazole; itraconazole; ketoconazole,"SDS: CHEBI:8984; NaCl: CHEBI:26710; CaCl2: CHEBI:3312; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; ketoconazole: CHEBI:47519, CAS:65277-42-1",,,,,gene deletion: full; gene complementation,,,YVS,29789366,PubMed,10.1128/mBio.00225-18,MBio. 2018 May 22;9(3). pii: e00225-18,gpalmer5@uthsc.edu,"C. albicans erg3Δ/Δ mutant was unable to cause lethality in the disseminated model, it induced pathology in a mouse model of vaginal infection and the erg3Δ/Δ mutant was also more resistant to fluconazole treatment than the wild type in both models of infection.",A Luna-Tapia 2018,2018,1 gene,Luna-Tapia-2018-Loss of Upc2p-Inducible ERG3 T,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11443,PHI:8122,UniProt,Q59VG6,GenBank,AOW26151,,,SC5314,erg3,chromosome 1,ERG3 ORF with 582 nucleotides (strain shprERG3) of 5' UTR and 303 nt of 3' UTR,,,,,5476,Candida albicans,,GP1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,"sterol Δ5,6-desaturase",,,,unaffected pathogenicity,,,,,,,,,,no,SDS; NaCl; CaCl2; fluconazole; voriconazole; itraconazole; ketoconazole,"SDS: CHEBI:8984; NaCl: CHEBI:26710; CaCl2: CHEBI:3312; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; ketoconazole: CHEBI:47519, CAS:65277-42-1",,,,,altered gene expression / gene regulation,,,YVS,29789366,PubMed,10.1128/mBio.00225-18,MBio. 2018 May 22;9(3). pii: e00225-18,gpalmer5@uthsc.edu,"C. albicans erg3Δ/Δ mutant was unable to cause lethality in the disseminated model, it induced pathology in a mouse model of vaginal infection and the erg3Δ/Δ mutant was also more resistant to fluconazole treatment than the wild type in both models of infection.",A Luna-Tapia 2018,2018,1 gene,Luna-Tapia-2018-Loss of Upc2p-Inducible ERG3 T,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11444,PHI:8122,UniProt,Q59VG6,GenBank,AOW26151,,,SC5314,erg3,chromosome 1,ERG3 ORF with 1000 nucleotides (strain lnprERG3) of 5' UTR and 303 nt of 3' UTR,,,,,5476,Candida albicans,,GP1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,"sterol Δ5,6-desaturase",,,,unaffected pathogenicity,,,,,,,,,,no,SDS; NaCl; CaCl2; fluconazole; voriconazole; itraconazole; ketoconazole,"SDS: CHEBI:8984; NaCl: CHEBI:26710; CaCl2: CHEBI:3312; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; ketoconazole: CHEBI:47519, CAS:65277-42-1",,,,,altered gene expression / gene regulation,,,YVS,29789366,PubMed,10.1128/mBio.00225-18,MBio. 2018 May 22;9(3). pii: e00225-18,gpalmer5@uthsc.edu,"C. albicans erg3Δ/Δ mutant was unable to cause lethality in the disseminated model, it induced pathology in a mouse model of vaginal infection and the erg3Δ/Δ mutant was also more resistant to fluconazole treatment than the wild type in both models of infection.",A Luna-Tapia 2018,2018,1 gene,Luna-Tapia-2018-Loss of Upc2p-Inducible ERG3 T,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11445,PHI:8122,UniProt,Q59VG6,GenBank,AOW26151,,,SC5314,erg3,chromosome 1,ERG3 ORF with 582 nucleotides (strain shprERG3) of 5' UTR and 303 nt of 3' UTR,,,,,5476,Candida albicans,,GP1,vaginal candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,vagina,"sterol Δ5,6-desaturase",,,,unaffected pathogenicity,,,,,,,,,,no,SDS; NaCl; CaCl2; fluconazole; voriconazole; itraconazole; ketoconazole,"SDS: CHEBI:8984; NaCl: CHEBI:26710; CaCl2: CHEBI:3312; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; ketoconazole: CHEBI:47519, CAS:65277-42-1",,,,,altered gene expression / gene regulation,,,YVS,29789366,PubMed,10.1128/mBio.00225-18,MBio. 2018 May 22;9(3). pii: e00225-18,gpalmer5@uthsc.edu,"C. albicans erg3Δ/Δ mutant was unable to cause lethality in the disseminated model, it induced pathology in a mouse model of vaginal infection and the erg3Δ/Δ mutant was also more resistant to fluconazole treatment than the wild type in both models of infection.",A Luna-Tapia 2018,2018,1 gene,Luna-Tapia-2018-Loss of Upc2p-Inducible ERG3 T,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11446,PHI:8122,UniProt,Q59VG6,GenBank,AOW26151,,,SC5314,erg3,chromosome 1,ERG3 ORF with 1000 nucleotides (strain lnprERG3) of 5' UTR and 303 nt of 3' UTR,,,,,5476,Candida albicans,,GP1,vaginal candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,vagina,"sterol Δ5,6-desaturase",,,,unaffected pathogenicity,,,,,,,,,,no,SDS; NaCl; CaCl2; fluconazole; voriconazole; itraconazole; ketoconazole,"SDS: CHEBI:8984; NaCl: CHEBI:26710; CaCl2: CHEBI:3312; fluconazole: CHEBI:46081, CAS:86386-73-4; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; ketoconazole: CHEBI:47519, CAS:65277-42-1",,,,,altered gene expression / gene regulation,,,YVS,29789366,PubMed,10.1128/mBio.00225-18,MBio. 2018 May 22;9(3). pii: e00225-18,gpalmer5@uthsc.edu,"C. albicans erg3Δ/Δ mutant was unable to cause lethality in the disseminated model, it induced pathology in a mouse model of vaginal infection and the erg3Δ/Δ mutant was also more resistant to fluconazole treatment than the wild type in both models of infection.",A Luna-Tapia 2018,2018,1 gene,Luna-Tapia-2018-Loss of Upc2p-Inducible ERG3 T,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11447,PHI:8123,UniProt,Q1R2U0,GenBank,ABE10324,,,UTI89,CNF1,,CNF1-C866S,,,,,562,Escherichia coli,,392 ISS,extraintestinal infection,primates,9606,Homo sapiens (related: human),,,,monocyte-derived dendritic cell,cytotoxic necrotizing factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29738516,PubMed,10.3390/ijms19051408,Int J Mol Sci. 2018 May 8;19(5). pii: E1408,thorkr@sund.ku.dk,"A catalytically inactive form of the toxin did not induce moDC maturation, indicating that the enzymatic activity of CNF1 triggers immature moDCs to undergo phenotypic and functional maturation.",L Gall-Mas 2018,2018,1 gene,Gall-Mas-2018-The Bacterial Toxin CNF1 Induces,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11448,PHI:8124,UniProt,G4N4I8,GenBank,EHA52003,,,70-15,Rtt109 (MGG_05969),chromosome 3,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdong,,,leaf,histone acetyltransferase,,,,reduced virulence,,no,,,,reduced,,reduced; aberrant,wild type,no,hydroxyurea; bleomycin; methyl methanesulphonate (MMS); hydrogen peroxide (H2O2); camptothecin,hydroxyurea: CHEBI:44423; bleomycin: CHEBI:22907; methyl methanesulfonate (MMS): CHEBI:25255; hydrogen peroxide (H2O2): CHEBI:16240; camptothecin: CHEBI:27656,,,,,gene deletion: full; gene complementation,,,YVS,29856240,PubMed,10.1094/MPMI-01-18-0015-R,Mol Plant Microbe Interact. 2018 Jun 1,yonglee@snu.ac.kr,"Targeted deletion of MoRtt109 resulted in significant reduction in acetylation of H3K56 and rendered the fungus defective in hyphal growth and asexual reproduction, furthermore, the deletion mutant displayed hypersensitivity to genotoxic agents.",S Kwon 2018,2018,1 gene,Kwon-2018-Role of the histone acetyltransferas,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11449,PHI:8125,UniProt,P29847,GenBank,CAA42163,,,LT2,cysE,,,,,,PHI:8126,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,serine acetyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; chemical complementation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11450,PHI:8126,UniProt,P37413,GenBank,AAL23006,,,LT2; SGSC 1412; ATCC 700720,metA,,,,,,PHI:8125,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,homoserine O-succinyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; chemical complementation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11451,PHI:8127,UniProt,Q8ZKP2,GenBank,AAL22927,,,LT2; SGSC 1412; ATCC 700720,glpF,,,,,,PHI:8128; PHI:8129; PHI:8130; PHI:8131,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,glycerol diffusion MIP channel,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11452,PHI:8128,UniProt,Q8ZKP3,GenBank,AAL22926,,,LT2; SGSC 1412; ATCC 700720,glpK,,,,,,PHI:8127; PHI:8129; PHI:8130; PHI:8131,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,glycerol kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11453,PHI:8129,UniProt,Q8ZKM9,GenBank,AAL22948,,,LT2; SGSC 1412; ATCC 700720,gldA,,,,,,PHI:8127; PHI:8128; PHI:8130; PHI:8131,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,"glycerol dehydrogenase, NAD",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11454,PHI:8130,UniProt,Q8ZNG6,GenBank,AAL21184,,,LT2; SGSC 1412; ATCC 700720,GlpT,,,,,,PHI:8127; PHI:8128; PHI:8129; PHI:8131,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,"MFS family, sn-glycerol-3-phosphate transport protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11455,PHI:8131,UniProt,Q7CPK0,GenBank,AAL22417,,,LT2; SGSC 1412; ATCC 700720,ugpB,,,,,,PHI:8127; PHI:8128; PHI:8129; PHI:8130,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,Sn-glycerol-3-phosphate-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11456,PHI:8132,UniProt,P63521,GenBank,AAL20733,,,LT2; SGSC 1412; ATCC 700720,fadD,,,,,,PHI:8133,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,acyl-CoA synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11457,PHI:8133,,no data found,GenBank,ASF64156,,,TW-Stm6,fadK,,,,,,PHI:8132,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,cyclohexanecarboxylate-CoA ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11458,PHI:8134,UniProt,P0A2C9,GenBank,AAC38650,,,LT2,fabG,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,3-oxoacyl-[acyl-carrier-protein] reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11459,PHI:8135,UniProt,Q8ZM69,GenBank,AAL21937,,,LT2; SGSC 1412; ATCC 700720,serA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,D-3-phosphoglycerate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11460,PHI:8136,UniProt,P25081,GenBank,AAL20387,,,LT2; SGSC 1412; ATCC 700720,manA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,mannose-6-phosphate isomerase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation; chemical complementation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11461,PHI:8137,UniProt,H9L499,GenBank,AAL21013,,,LT2; SGSC 1412; ATCC 700720,gmd,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,"GDP-mannose 4,6-dehydratase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11462,PHI:8138,UniProt,P26406,GenBank,AAL20986,,,LT2; SGSC 1412; ATCC 700720,rfbP,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eudicots,3879,Medicago sativa (related: alfalfa),,,,seedling,undecaprenyl-phosphate galactose phosphotransferase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29867780,PubMed,10.3389/fmicb.2018.00695,Front Microbiol. 2018 May 8;9:695,jeri.barak@wisc.edu,"Common, simple molecules such as sugars, organic acids and amino acids comprised the diet of S. enterica in both plants and animals.",G Kwan 2018,2018,14 genes,Kwan-2018-Few Differences in Metabolic Network,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11463,PHI:8139,UniProt,A0A0F6B136,GenBank,ACY88218,,,14028S,SlyA (STM14_1742),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,transcription factor,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide; sodium hypochlorite,hydrogen peroxide: CHEBI:16240; sodium hypochlorite: CHEBI:32146,,,,,gene mutation; gene complementation,,,YVS,29857034,PubMed,10.1016/j.resmic.2018.04.003,Res Microbiol. 2018 May 29. pii: S0923-2508(18)30059-7,claudiasaavedrasanchez@gmail.com,The transcriptional factor SlyA was involved in the oxidative stress response and invasion of murine macrophages.,C E Cabezas 2018,2018,1 gene,Cabezas-2018-The transcription factor SlyA fro,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11464,PHI:8140,UniProt,A0A0H2ZNY6,GenBank,ABJ54587,,,D39,tatD (SPD_1789),,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; blood; spleen,extracellular vesicle associated endodeoxyribonuclease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29789571,PubMed,10.1038/s41598-018-25865-z,Sci Rep. 2018 May 22;8(1):7985,devinder@nii.ac.in,"TatD deficient pneumococci showed lower bacterial load in lungs, blood and spleen in a murine sepsis model compared to wildtype strain, and showed less severe lung pathology and compromised virulence.",H Jhelum 2018,2018,1 gene,Jhelum-2018-A novel extracellular vesicle-asso,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11465,PHI:8141,UniProt,Q9KTQ6,GenBank,AAF94004,,,N16961,acfC (VC_0841),chromosome I,,,,,,666,Vibrio cholerae,,S2CHK17,cholera,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,accessory colonisation factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29849063,PubMed,10.1038/s41598-018-26570-7,Sci Rep. 2018 May 30;8(1):8390,Brendan.wren@lshtm.ac.uk,Results indicated that AcfC might be a periplasmic sulfate-binding protein that affected chemotaxis towards mucin and bacterial infectivity in the infant rabbit model of cholera.,E Valiente 2018,2018,1 gene,Valiente-2018-Vibrio cholerae accessory coloni,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11466,PHI:8141,UniProt,Q9KTQ6,GenBank,AAF94004,,,N16961,acfC (VC_0841),chromosome I,,,,,,666,Vibrio cholerae,,S2CHK17,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,small intestine,accessory colonisation factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29849063,PubMed,10.1038/s41598-018-26570-7,Sci Rep. 2018 May 30;8(1):8390,Brendan.wren@lshtm.ac.uk,Results indicated that AcfC might be a periplasmic sulfate-binding protein that affected chemotaxis towards mucin and bacterial infectivity in the infant rabbit model of cholera.,E Valiente 2018,2018,1 gene,Valiente-2018-Vibrio cholerae accessory coloni,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11467,PHI:8142,UniProt,A0A2P5GZ81,GenBank,POQ44667,,,CDPHFDLB-FM17-00100,InlP,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,carnivores,9612,Canis lupus (related: gray wolf),subsp. familiaris MDCK cell line,,,MDCK cell,"internalin P, secreted virulence factor",,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,YVS,29847585,PubMed,10.1371/journal.ppat.1007094,PLoS Pathog. 2018 May 30;14(5):e1007094,abakardjiev@vir.bio,"Host gene alteration data available for afadin (AF-6). L. monocytogenes ΔinlP mutants were deficient in their ability to form actin-rich protrusions from the basal face of polarized epithelial monolayers, a necessary step in the crossing of such monolayers (transcytosis) and a similar phenotype was observed for bacteria expressing an internal in-frame deletion in inlP (inlPΔLRR5) that specifically disrupts its interaction with afadin.",C Faralla 2018,2018,2 genes,Faralla-2018-Listeria monocytogenes InlP inter,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11468,PHI:8143,UniProt,P33379,GenBank,CAA42407,,,EGD,actA,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,carnivores,9612,Canis lupus (related: gray wolf),subsp. familiaris MDCK cell line,,,MDCK cell,actin assembly-inducing protein,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,YVS,29847585,PubMed,10.1371/journal.ppat.1007094,PLoS Pathog. 2018 May 30;14(5):e1007094,abakardjiev@vir.bio,"Host gene alteration data available for afadin (AF-6). L. monocytogenes ΔinlP mutants were deficient in their ability to form actin-rich protrusions from the basal face of polarized epithelial monolayers, a necessary step in the crossing of such monolayers (transcytosis) and a similar phenotype was observed for bacteria expressing an internal in-frame deletion in inlP (inlPΔLRR5) that specifically disrupts its interaction with afadin.",C Faralla 2018,2018,2 genes,Faralla-2018-Listeria monocytogenes InlP inter,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11469,PHI:8142,UniProt,A0A2P5GZ81,GenBank,POQ44667,,,CDPHFDLB-FM17-00100,InlP,,inlP ΔLRR5 (Δamino acids 174-195),,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,carnivores,9612,Canis lupus (related: gray wolf),subsp. familiaris MDCK cell line,,,MDCK cell,"internalin P, secreted virulence factor",,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: partial,,,YVS,29847585,PubMed,10.1371/journal.ppat.1007094,PLoS Pathog. 2018 May 30;14(5):e1007094,abakardjiev@vir.bio,"Host gene alteration data available for afadin (AF-6). L. monocytogenes ΔinlP mutants were deficient in their ability to form actin-rich protrusions from the basal face of polarized epithelial monolayers, a necessary step in the crossing of such monolayers (transcytosis) and a similar phenotype was observed for bacteria expressing an internal in-frame deletion in inlP (inlPΔLRR5) that specifically disrupts its interaction with afadin.",C Faralla 2018,2018,2 genes,Faralla-2018-Listeria monocytogenes InlP inter,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11470,PHI:8144,UniProt,B8N1G3,GenBank,EED55756,,,NRRL3357,CDC14,,,,,,,5059,Aspergillus flavus,,CA14 PTS,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,protein-tyrosine phosphatase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,NaCl; KCl; calcofluor white; Congo red; H2O2; MMS,NaCl: CHEBI:26710; KCl: CHEBI:32588; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; methyl methanesulfonate (MMS): CHEBI:25255,,,,,gene deletion: full; gene complementation,,,YVS,29849063,PubMed,10.3389/fcimb.2018.00141,Front Cell Infect Microbiol. 2018 May 7;8:141,wshyyl@sina.com,AflCDC14 deletion mutant had significant increase in aflatoxin production.,G Yang 2018,2018,1 gene,Yang-2018-The Aspergillus flavus Phosphatase C,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11471,PHI:8144,UniProt,B8N1G3,GenBank,EED55756,,,NRRL3357,CDC14,,,,,,,5059,Aspergillus flavus,,CA14 PTS,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,cotyledon,protein-tyrosine phosphatase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,NaCl; KCl; calcofluor white; Congo red; H2O2; MMS,NaCl: CHEBI:26710; KCl: CHEBI:32588; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; methyl methanesulfonate (MMS): CHEBI:25255,,,,,gene deletion: full; gene complementation,,,YVS,29849063,PubMed,10.3389/fcimb.2018.00141,Front Cell Infect Microbiol. 2018 May 7;8:141,wshyyl@sina.com,AflCDC14 deletion mutant had significant increase in aflatoxin production.,G Yang 2018,2018,1 gene,Yang-2018-The Aspergillus flavus Phosphatase C,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11472,PHI:8145,UniProt,W7N9I2,GenBank,EWG53137,,,7600,fvebp1 (FVEG_11622),chromosome 7,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,mesocotyl,hypothetical protein harboring emopamil-binding protein (EBP) domain,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29844502,PubMed,10.1038/s41598-018-26505-2,Sci Rep. 2018 May 29;8(1):8310,wbshim@tamu.edu,"The data suggested that FvSYN1 and FvEBP1 were important for regulating the expression of closely correlated genes, further providing evidence that these are important hub genes of their respective subnetworks.",M S Kim 2018,2018,2 genes,Kim-2018-Characterizing co-expression networks,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11473,PHI:8146,UniProt,W7LVV1,GenBank,EWG36676,,,7600,fvsyn1 (FVEG_00594),chromosome 1,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,mesocotyl,putative protein harboring syntaxin N-terminal domain and SNARE domain,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29844502,PubMed,10.1038/s41598-018-26505-2,Sci Rep. 2018 May 29;8(1):8310,wbshim@tamu.edu,"The data suggested that FvSYN1 and FvEBP1 were important for regulating the expression of closely correlated genes, further providing evidence that these are important hub genes of their respective subnetworks.",M S Kim 2018,2018,2 genes,Kim-2018-Characterizing co-expression networks,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11474,PHI:8147,,no data found,GenBank,AGB10278,,,BB22OP,luxM,chromosome 1,,,,,,670,Vibrio parahaemolyticus,,ATCC 33847,gastrointestinal disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,erythrocyte,N-(3-hydroxybutanoyl)-L-homoserine lactone synthase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,29785633,PubMed,10.1007/s00284-018-1508-y,Curr Microbiol. 2018 May 21,wangylchina@163.com,"Thermostable direct hemolysin gene (tdh) was negatively regulated by luxM and positively regulated by luxS, and the biofilm formation was negatively regulated by both luxS and luxM.",M Guo 2018,2018,2 genes,Guo-2018-Regulation of Thermostable Direct Hem,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11475,PHI:8148,,no data found,GenBank,AGB10818,,,BB22OP,luxS,chromosome 1,,,,,,670,Vibrio parahaemolyticus,,ATCC 33847,gastrointestinal disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,erythrocyte,S-ribosylhomocysteine lyase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29785633,PubMed,10.1007/s00284-018-1508-y,Curr Microbiol. 2018 May 21,wangylchina@163.com,"Thermostable direct hemolysin gene (tdh) was negatively regulated by luxM and positively regulated by luxS, and the biofilm formation was negatively regulated by both luxS and luxM.",M Guo 2018,2018,2 genes,Guo-2018-Regulation of Thermostable Direct Hem,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11476,PHI:8149,,no data found,GenBank,X86077.1,,,,ROPIP1,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei race A6,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,non-long terminal repeat retroelement Eg-R1,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: transient overexpression,,,YVS,29757394,PubMed,10.1093/jxb/ery174,J Exp Bot. 2018 May 11,hueckelhoven@wzw.tum.de,The data suggested that Bgh ROPIP targeted HvRACB and manipulated host cell microtubule organization for facilitated host cell entry.,M Nottensteiner 2018,2018,1 gene,Nottensteiner-2018-A Barley Powdery Mildew Fun,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11477,PHI:8149,,no data found,GenBank,X86077.1,,,,ROPIP1,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei race A6,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,non-long terminal repeat retroelement Eg-R1,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing: gene complementation,,,YVS,29757394,PubMed,10.1093/jxb/ery174,J Exp Bot. 2018 May 11,hueckelhoven@wzw.tum.de,The data suggested that Bgh ROPIP targeted HvRACB and manipulated host cell microtubule organization for facilitated host cell entry.,M Nottensteiner 2018,2018,1 gene,Nottensteiner-2018-A Barley Powdery Mildew Fun,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11478,PHI:8150,,no data found,GenBank,AIX04136,,,CNCTC 10/84,brpA,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; vagina; kidney; spleen,biofilm regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,chloramphenicol; LL-37; hydrogen peroxide,chloramphenicol: CHEBI:17698; LL-37: CHEBI:81664; H2O2: CHEBI:16240,,,,,gene disruption; gene complementation,,,YVS,29868829,PubMed,10.1093/infdis/jiy341,J Infect Dis. 2018 Jun 4,vnizet@ucsd.edu,GBS ΔbrpA showed decreased acid tolerance and stimulated increased neutrophil reactive oxygen species and proved more susceptible to human and murine blood and neutrophil killing.,K A Patras 2018,2018,1 gene,Patras-2018-Group B Streptococcus Biofilm Regu,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11479,PHI:8150,,no data found,GenBank,AIX04136,,,CNCTC 10/84,brpA,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood,biofilm regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,chloramphenicol; LL-37; hydrogen peroxide,chloramphenicol: CHEBI:17698; LL-37: CHEBI:81664; H2O2: CHEBI:16240,,,,,gene disruption; gene complementation,,,YVS,29868829,PubMed,10.1093/infdis/jiy341,J Infect Dis. 2018 Jun 4,vnizet@ucsd.edu,GBS ΔbrpA showed decreased acid tolerance and stimulated increased neutrophil reactive oxygen species and proved more susceptible to human and murine blood and neutrophil killing.,K A Patras 2018,2018,1 gene,Patras-2018-Group B Streptococcus Biofilm Regu,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11480,PHI:8151,UniProt,R9RJ65,GenBank,AGM49306,,,SS2-1,stk,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cerebrospinal fluid,serine/threonine kinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29797543,PubMed,10.1111/cmi.12862,Cell Microbiol. 2018 May 24:e12862,fhj@njau.edu.cn,"In vitro, compared with ZY05719, the ability of the stk-deficient strain (Δstk) to adhere to and invade both hBMECs and bEnd.3 cells, as well as to cross the BBB, was significantly attenuated.",L Rui 2018,2018,1 gene,Rui-2018-The serine_threonine protein kinase o,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11481,PHI:8152,UniProt,B8MXT5,GenBank,EED57177,,,NRRL3357,aflpex5 (AFLA_078720),,,,,,,5059,Aspergillus flavus,,CA14 PTS,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,peroxisomal protein importer,,,,reduced virulence,yes,,,,,reduced,reduced,reduced,reduced,no,H2O2; menadione sodium bisulfite (MSB); calcofluor white; sodium dodecyl sulfate; diamide,H2O2: CHEBI:16240; menadione sodium bisulfite (MSB): CHEBI:63928; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,29869688,PubMed,10.1007/s00294-018-0851-7,Curr Genet. 2018 Jun 5,wshyyl@sina.com,"Deletion of AflPex5 caused defects in sporulation, sclerotial formation, aflatoxin biosynthesis, stress response, and plant infection.",F Zhang 2018,2018,1 gene,Zhang-2018-Contribution of peroxisomal protein,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11482,PHI:8152,UniProt,B8MXT5,GenBank,EED57177,,,NRRL3357,aflpex5 (AFLA_078720),,,,,,,5059,Aspergillus flavus,,CA14 PTS,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,cotyledon,peroxisomal protein importer,,,,reduced virulence,yes,,,,,reduced,reduced,reduced,reduced,no,H2O2; menadione sodium bisulfite (MSB); calcofluor white; sodium dodecyl sulfate; diamide,H2O2: CHEBI:16240; menadione sodium bisulfite (MSB): CHEBI:63928; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,29869688,PubMed,10.1007/s00294-018-0851-7,Curr Genet. 2018 Jun 5,wshyyl@sina.com,"Deletion of AflPex5 caused defects in sporulation, sclerotial formation, aflatoxin biosynthesis, stress response, and plant infection.",F Zhang 2018,2018,1 gene,Zhang-2018-Contribution of peroxisomal protein,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11483,PHI:8153,UniProt,B0Y7G6,GenBank,EDP49347,,,A1163,aceA (AFUB_073740),,,,,,,746128,Aspergillus fumigatus,,A1160,invasive aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,lung,putative Cu detoxification transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29845725,PubMed,10.1111/cmi.12864,Cell Microbiol. 2018 May 29:e12864,zhendong_cai@126.com,"Cys, RGHR, and KGRP residues within the predicted Zn module and Cu-regulatory domain region of AfAceA are essential for its role in Cu and Zn tolerance and Cys residues of AfAceA within N-terminal region have a key role for virulence in mice.",Z Cai 2018,2018,1 gene,Cai-2018-The Aspergillus fumigatus transcripti,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11484,PHI:8153,UniProt,B0Y7G6,GenBank,EDP49347,,,A1163,aceA (AFUB_073740),,AfAceAC10S; AfAceAC45S,,,,,746128,Aspergillus fumigatus,,A1160,invasive aspergillosis,rodents,10090,Mus musculus (related: house mouse),,,,lung,putative Cu detoxification transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29845725,PubMed,10.1111/cmi.12864,Cell Microbiol. 2018 May 29:e12864,zhendong_cai@126.com,"Cys, RGHR, and KGRP residues within the predicted Zn module and Cu-regulatory domain region of AfAceA are essential for its role in Cu and Zn tolerance and Cys residues of AfAceA within N-terminal region have a key role for virulence in mice.",Z Cai 2018,2018,1 gene,Cai-2018-The Aspergillus fumigatus transcripti,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11485,PHI:8154,UniProt,Q5AME2,GenBank,AOW28880,,,SC5314,Aro1 (orf19.4704),chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,aromatic multifunctional enzyme which catalyzes reactions of shikimate pathway to synthesize aromatic amino acids,,,shikimate pathway,reduced virulence,,,,,,,,reduced,,no,calcoflour white,calcoflour white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,29807722,PubMed,10.1016/j.jmii.2018.04.002,J Microbiol Immunol Infect. 2018 May 17. pii: S1684-1182(18)30105-1,cylan@life.nthu.edu.tw,C. albicans Aro1 negatively affected cell adhesion and biofilm formation.,Y C Yeh 2018,2018,1 gene,Yeh-2018-Candida albicans Aro1 affects cell wa,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11486,PHI:8155,UniProt,Q63W50,GenBank,CAH35035,,,K96243,BPSL1039,chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,integral trans-membrane protein of ABC transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29771915,PubMed,10.1371/journal.pone.0196202,PLoS One. 2018 May 17;13(5):e0196202,sunee.kor@mahidol.ac.th,"BPSL1039/BPSL1040 ABC transporter enhances anaerobic growth of B. pseudomallei through nitrate respiration, hence there was a significantly reduced amount of growth compared with the wildtype strain under anaerobic conditions.",P Pinweha 2018,2018,2 genes,Zhang-2018-Contribution of peroxisomal protein,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11487,PHI:8156,UniProt,Q63W49,GenBank,CAH35036,,,K96243,BPSL1040,chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,"putative ABC transport system, ATP-binding protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29771915,PubMed,10.1371/journal.pone.0196202,PLoS One. 2018 May 17;13(5):e0196202,sunee.kor@mahidol.ac.th,"BPSL1039/BPSL1040 ABC transporter enhances anaerobic growth of B. pseudomallei through nitrate respiration, hence there was a significantly reduced amount of growth compared with the wildtype strain under anaerobic conditions.",P Pinweha 2018,2018,2 genes,Zhang-2018-Contribution of peroxisomal protein,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11488,PHI:8155,UniProt,Q63W50,GenBank,CAH35035,,,K96243,BPSL1039,chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,integral trans-membrane protein of ABC transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29771915,PubMed,10.1371/journal.pone.0196202,PLoS One. 2018 May 17;13(5):e0196202,sunee.kor@mahidol.ac.th,"BPSL1039/BPSL1040 ABC transporter enhances anaerobic growth of B. pseudomallei through nitrate respiration, hence there was a significantly reduced amount of growth compared with the wildtype strain under anaerobic conditions.",P Pinweha 2018,2018,2 genes,Zhang-2018-Contribution of peroxisomal protein,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11489,PHI:8156,UniProt,Q63W49,GenBank,CAH35036,,,K96243,BPSL1040,chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,"putative ABC transport system, ATP-binding protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29771915,PubMed,10.1371/journal.pone.0196202,PLoS One. 2018 May 17;13(5):e0196202,sunee.kor@mahidol.ac.th,"BPSL1039/BPSL1040 ABC transporter enhances anaerobic growth of B. pseudomallei through nitrate respiration, hence there was a significantly reduced amount of growth compared with the wildtype strain under anaerobic conditions.",P Pinweha 2018,2018,2 genes,Zhang-2018-Contribution of peroxisomal protein,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11490,PHI:8155,UniProt,Q63W50,GenBank,CAH35035,,,K96243,BPSL1039,chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,integral trans-membrane protein of ABC transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29771915,PubMed,10.1371/journal.pone.0196202,PLoS One. 2018 May 17;13(5):e0196202,sunee.kor@mahidol.ac.th,"BPSL1039/BPSL1040 ABC transporter enhances anaerobic growth of B. pseudomallei through nitrate respiration, hence there was a significantly reduced amount of growth compared with the wildtype strain under anaerobic conditions. cervical epitheloid cells",P Pinweha 2018,2018,2 genes,Zhang-2018-Contribution of peroxisomal protein,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11491,PHI:8156,UniProt,Q63W49,GenBank,CAH35036,,,K96243,BPSL1040,chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,"putative ABC transport system, ATP-binding protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29771915,PubMed,10.1371/journal.pone.0196202,PLoS One. 2018 May 17;13(5):e0196202,sunee.kor@mahidol.ac.th,"BPSL1039/BPSL1040 ABC transporter enhances anaerobic growth of B. pseudomallei through nitrate respiration, hence there was a significantly reduced amount of growth compared with the wildtype strain under anaerobic conditions. cervical epitheloid cells",P Pinweha 2018,2018,2 genes,Zhang-2018-Contribution of peroxisomal protein,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11492,PHI:8157,UniProt,P77568,GenBank,AAA88426,,,PAO1,fimS,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histidine sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11493,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11494,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54A,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11495,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54E,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11496,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11497,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54A,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11498,PHI:8159,UniProt,Q06198,GenBank,AAC43714,,,PAO1,algu,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,sigma factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11499,PHI:8160,UniProt,Q51534,GenBank,AAA93500,,,PAO1,pilW,,,,,,PHI:8159,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11500,PHI:8159,UniProt,Q06198,GenBank,AAC43714,,,PAO1,algu,,,,,,PHI:8160,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11501,PHI:8161,UniProt,Q9HVM9,GenBank,AE004869_5,,,PAO1,pilX,,,,,,PHI:8159,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11502,PHI:8159,UniProt,Q06198,GenBank,AAC43714,,,PAO1,algu,,,,,,PHI:8161,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11503,PHI:8162,UniProt,Q9HVM8,GenBank,AE004869_6,,,PAO1,pilY1,,,,,,PHI:8159,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative adhesion,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11504,PHI:8159,UniProt,Q06198,GenBank,AAC43714,,,PAO1,algu,,,,,,PHI:8162,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11505,PHI:8160,UniProt,Q51534,GenBank,AAA93500,,,PAO1,pilW,,,,,,PHI:8161; PHI:8162,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11506,PHI:8161,UniProt,Q9HVM9,GenBank,AE004869_5,,,PAO1,pilX,,,,,,PHI:8160; PHI:8162,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11507,PHI:8162,UniProt,Q9HVM8,GenBank,AE004869_6,,,PAO1,pilY1,,,,,,PHI:8160; PHI:8161,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative adhesion,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11508,PHI:8160,UniProt,Q51534,GenBank,AAA93500,,,PAO1,pilW,,,,,,PHI:8157,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11509,PHI:8157,UniProt,P77568,GenBank,AAA88426,,,PAO1,fimS,,,,,,PHI:8160,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histidine sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11510,PHI:8161,UniProt,Q9HVM9,GenBank,AE004869_5,,,PAO1,pilX,,,,,,PHI:8157,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11511,PHI:8157,UniProt,P77568,GenBank,AAA88426,,,PAO1,fimS,,,,,,PHI:8161,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histidine sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11512,PHI:8162,UniProt,Q9HVM8,GenBank,AE004869_6,,,PAO1,pilY1,,,,,,PHI:8157,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative adhesion,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11513,PHI:8157,UniProt,P77568,GenBank,AAA88426,,,PAO1,fimS,,,,,,PHI:8162,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histidine sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11514,PHI:8160,UniProt,Q51534,GenBank,AAA93500,,,PAO1,pilW,,,,,,PHI:8158,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11515,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,,,,,PHI:8160,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11516,PHI:8161,UniProt,Q9HVM9,GenBank,AE004869_5,,,PAO1,pilX,,,,,,PHI:8158,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11517,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,,,,,PHI:8161,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11518,PHI:8162,UniProt,Q9HVM8,GenBank,AE004869_6,,,PAO1,pilY1,,,,,,PHI:8158,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative adhesion,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11519,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,,,,,PHI:8162,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11520,PHI:8160,UniProt,Q51534,GenBank,AAA93500,,,PAO1,pilW,,,,,,PHI:8158,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11521,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54A,,,,PHI:8160,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11522,PHI:8161,UniProt,Q9HVM9,GenBank,AE004869_5,,,PAO1,pilX,,,,,,PHI:8158,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11523,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54A,,,,PHI:8161,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11524,PHI:8162,UniProt,Q9HVM8,GenBank,AE004869_6,,,PAO1,pilY1,,,,,,PHI:8158,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative adhesion,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11525,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54A,,,,PHI:8162,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11526,PHI:8163,UniProt,Q9HW69,GenBank,AAG07720,,,PAO1,sadC,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,inner membrane-localized diguanylate cyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11527,PHI:8163,UniProt,Q9HW69,GenBank,AAG07720,,,PAO1,sadC,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,inner membrane-localized diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11528,PHI:8157,UniProt,P77568,GenBank,AAA88426,,,PAO1,fimS,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histidine sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11529,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11530,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54A,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11531,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54E,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11532,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11533,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54A,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11534,PHI:8159,UniProt,Q06198,GenBank,AAC43714,,,PAO1,algu,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,sigma factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11535,PHI:8160,UniProt,Q51534,GenBank,AAA93500,,,PAO1,pilW,,,,,,PHI:8159,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11536,PHI:8159,UniProt,Q06198,GenBank,AAC43714,,,PAO1,algu,,,,,,PHI:8160,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11537,PHI:8161,UniProt,Q9HVM9,GenBank,AE004869_5,,,PAO1,pilX,,,,,,PHI:8159,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11538,PHI:8159,UniProt,Q06198,GenBank,AAC43714,,,PAO1,algu,,,,,,PHI:8161,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11539,PHI:8162,UniProt,Q9HVM8,GenBank,AE004869_6,,,PAO1,pilY1,,,,,,PHI:8159,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative adhesion,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11540,PHI:8159,UniProt,Q06198,GenBank,AAC43714,,,PAO1,algu,,,,,,PHI:8162,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11541,PHI:8160,UniProt,Q51534,GenBank,AAA93500,,,PAO1,pilW,,,,,,PHI:8161; PHI:8162,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11542,PHI:8161,UniProt,Q9HVM9,GenBank,AE004869_5,,,PAO1,pilX,,,,,,PHI:8160; PHI:8162,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11543,PHI:8162,UniProt,Q9HVM8,GenBank,AE004869_6,,,PAO1,pilY1,,,,,,PHI:8160; PHI:8161,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative adhesion,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11544,PHI:8160,UniProt,Q51534,GenBank,AAA93500,,,PAO1,pilW,,,,,,PHI:8157,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11545,PHI:8157,UniProt,P77568,GenBank,AAA88426,,,PAO1,fimS,,,,,,PHI:8160,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histidine sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11546,PHI:8161,UniProt,Q9HVM9,GenBank,AE004869_5,,,PAO1,pilX,,,,,,PHI:8157,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11547,PHI:8157,UniProt,P77568,GenBank,AAA88426,,,PAO1,fimS,,,,,,PHI:8161,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histidine sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11548,PHI:8162,UniProt,Q9HVM8,GenBank,AE004869_6,,,PAO1,pilY1,,,,,,PHI:8157,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative adhesion,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11549,PHI:8157,UniProt,P77568,GenBank,AAA88426,,,PAO1,fimS,,,,,,PHI:8162,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histidine sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11550,PHI:8160,UniProt,Q51534,GenBank,AAA93500,,,PAO1,pilW,,,,,,PHI:8158,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11551,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,,,,,PHI:8160,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11552,PHI:8161,UniProt,Q9HVM9,GenBank,AE004869_5,,,PAO1,pilX,,,,,,PHI:8158,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11553,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,,,,,PHI:8161,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11554,PHI:8162,UniProt,Q9HVM8,GenBank,AE004869_6,,,PAO1,pilY1,,,,,,PHI:8158,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative adhesion,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11555,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,,,,,PHI:8162,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11556,PHI:8160,UniProt,Q51534,GenBank,AAA93500,,,PAO1,pilW,,,,,,PHI:8158,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11557,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54A,,,,PHI:8160,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11558,PHI:8161,UniProt,Q9HVM9,GenBank,AE004869_5,,,PAO1,pilX,,,,,,PHI:8158,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,minor pilin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11559,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54A,,,,PHI:8161,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11560,PHI:8162,UniProt,Q9HVM8,GenBank,AE004869_6,,,PAO1,pilY1,,,,,,PHI:8158,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative adhesion,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11561,PHI:8158,UniProt,P26275,GenBank,AE004938_8,,,PAO1,algR,,D54A,,,,PHI:8162,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11562,PHI:8163,UniProt,Q9HW69,GenBank,AAG07720,,,PAO1,sadC,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,inner membrane-localized diguanylate cyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11563,PHI:8163,UniProt,Q9HW69,GenBank,AAG07720,,,PAO1,sadC,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,inner membrane-localized diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29775484,PubMed,10.1371/journal.ppat.1007074,PLoS Pathog. 2018 May 18;14(5):e1007074,burrowl@mcmaster.ca,"Loss of specific minor pilins relieved feedback inhibition on FimS-AlgR, increasing transcription of the AlgR regulon and delaying C. elegans killing.",V A Marco 2018,2018,7 genes,Marko-2018-Pseudomonas aeruginosa type IV mino,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11564,PHI:8164,UniProt,Q2VSW6,GenBank,AKA32888,,,AB5075-UW,bfmR,,,,,,PHI:8165,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,peritoneum,two-component system response regulator protein,,,,reduced virulence,,,,,,,,,,no,mecillinam; imipenem; ceftazidime; aztreonam; sulbactam; ampicillin; carbenicillin; cephalexin; phosphomycin; MreB antagonist A22; ciprofloxacin,mecillinam: CHEBI:51208; imipenem: CHEBI:471744; ceftazidime: CHEBI:3508; aztreonam: CHEBI:161680; sulbactam: CHEBI:9321; ampicillin: CHEBI:28971; carbenicillin: CHEBI:3393; cephalexin: CHEBI:3534; phosphomycin: CHEBI:28915; ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,YVS,29795704,PubMed,10.1371/journal.ppat.1007030,PLoS Pathog. 2018 May 24;14(5):e1007030,ralph.isberg@tufts.edu,BfmS negatively regulates the resistance-promoting activities of BfmR.,E Geisinger 2018,2018,2 genes,Geisinger-2018-A global regulatory system link,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11565,PHI:8165,UniProt,Q2VSW5,GenBank,ODP67295,,,XH198,bfmS,,,,,,PHI:8164,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,peritoneum,sensory-transduction system receptor histidine kinase,,,,reduced virulence,,,,,,,,,,no,mecillinam; imipenem; ceftazidime; aztreonam; sulbactam; ampicillin; carbenicillin; cephalexin; phosphomycin; MreB antagonist A22; ciprofloxacin,mecillinam: CHEBI:51208; imipenem: CHEBI:471744; ceftazidime: CHEBI:3508; aztreonam: CHEBI:161680; sulbactam: CHEBI:9321; ampicillin: CHEBI:28971; carbenicillin: CHEBI:3393; cephalexin: CHEBI:3534; phosphomycin: CHEBI:28915; ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,YVS,29795704,PubMed,10.1371/journal.ppat.1007030,PLoS Pathog. 2018 May 24;14(5):e1007030,ralph.isberg@tufts.edu,BfmS negatively regulates the resistance-promoting activities of BfmR.,E Geisinger 2018,2018,2 genes,Geisinger-2018-A global regulatory system link,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11566,PHI:8165,UniProt,Q2VSW5,GenBank,ODP67295,,,XH198,bfmS,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,peritoneum,sensory-transduction system receptor histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,mecillinam; imipenem; ceftazidime; aztreonam; sulbactam; ampicillin; carbenicillin; cephalexin; phosphomycin; MreB antagonist A22; ciprofloxacin,mecillinam: CHEBI:51208; imipenem: CHEBI:471744; ceftazidime: CHEBI:3508; aztreonam: CHEBI:161680; sulbactam: CHEBI:9321; ampicillin: CHEBI:28971; carbenicillin: CHEBI:3393; cephalexin: CHEBI:3534; phosphomycin: CHEBI:28915; ciprofloxacin: CHEBI:100241,,,,,gene deletion: full,,,YVS,29795704,PubMed,10.1371/journal.ppat.1007030,PLoS Pathog. 2018 May 24;14(5):e1007030,ralph.isberg@tufts.edu,BfmS negatively regulates the resistance-promoting activities of BfmR.,E Geisinger 2018,2018,2 genes,Geisinger-2018-A global regulatory system link,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11567,PHI:8165,UniProt,Q2VSW5,GenBank,ODP67295,,,XH198,bfmS,,H234Q,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,peritoneum,sensory-transduction system receptor histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,mecillinam; imipenem; ceftazidime; aztreonam; sulbactam; ampicillin; carbenicillin; cephalexin; phosphomycin; MreB antagonist A22; ciprofloxacin,mecillinam: CHEBI:51208; imipenem: CHEBI:471744; ceftazidime: CHEBI:3508; aztreonam: CHEBI:161680; sulbactam: CHEBI:9321; ampicillin: CHEBI:28971; carbenicillin: CHEBI:3393; cephalexin: CHEBI:3534; phosphomycin: CHEBI:28915; ciprofloxacin: CHEBI:100241,,,,,gene deletion: full,,,YVS,29795704,PubMed,10.1371/journal.ppat.1007030,PLoS Pathog. 2018 May 24;14(5):e1007030,ralph.isberg@tufts.edu,BfmS negatively regulates the resistance-promoting activities of BfmR.,E Geisinger 2018,2018,2 genes,Geisinger-2018-A global regulatory system link,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11568,PHI:8166,UniProt,Q967R0,GenBank,AAP42139,,,CL Brener,UBP1,,,,,,,5693,Trypanosoma cruzi,353153,CL Brener,African trypanosomiasis,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,renal epithelial cell,RNA binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: ectopic expression,,,YVS,29864162,PubMed,10.1371/journal.ppat.1007059,PLoS Pathog. 2018 Jun 4;14(6):e1007059,acassola@iibintech.com.ar,Metacyclic trypomastigotes promoted by ectopic expression of TcUBP1-GFP were functional infective forms as shown by infection of VERO cells in culture.,M A Romaniuk 2018,2018,1 gene,Romaniuk-2018-Translational repression by an R,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11569,PHI:8167,,no data found,,,,,,talA,,,,,,,347,Xanthomonas oryzae,1009853,X11-5A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: biparental conjugation,,,YVS,29864161,PubMed,10.1371/journal.ppat.1007092,PLoS Pathog. 2018 Jun 4;14(6):e1007092,mathildehutin1@gmail.com,Mutation of talB in BAI3 resulted in a decrease of virulence partially complemented by the induction of OsERF#123.,T T Tran 2018,2018,9 genes,Tran-2018-Functional analysis of African Xanth,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11570,PHI:8168,UniProt,G7TEI1,GenBank,AEQ95160,,,BLS256,talB,,,,,,,347,Xanthomonas oryzae,1009853,X11-5A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: biparental conjugation,,,YVS,29864161,PubMed,10.1371/journal.ppat.1007092,PLoS Pathog. 2018 Jun 4;14(6):e1007092,mathildehutin1@gmail.com,Mutation of talB in BAI3 resulted in a decrease of virulence partially complemented by the induction of OsERF#123.,T T Tran 2018,2018,9 genes,Tran-2018-Functional analysis of African Xanth,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11571,PHI:8169,UniProt,G1FM79,GenBank,AEK86668,,,BAI3,talC,,,,,,,347,Xanthomonas oryzae,1009853,X11-5A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: biparental conjugation,,,YVS,29864161,PubMed,10.1371/journal.ppat.1007092,PLoS Pathog. 2018 Jun 4;14(6):e1007092,mathildehutin1@gmail.com,Mutation of talB in BAI3 resulted in a decrease of virulence partially complemented by the induction of OsERF#123.,T T Tran 2018,2018,9 genes,Tran-2018-Functional analysis of African Xanth,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11572,PHI:8170,,no data found,,,,,,talD,,,,,,,347,Xanthomonas oryzae,1009853,X11-5A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: biparental conjugation,,,YVS,29864161,PubMed,10.1371/journal.ppat.1007092,PLoS Pathog. 2018 Jun 4;14(6):e1007092,mathildehutin1@gmail.com,Mutation of talB in BAI3 resulted in a decrease of virulence partially complemented by the induction of OsERF#123.,T T Tran 2018,2018,9 genes,Tran-2018-Functional analysis of African Xanth,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11573,PHI:8171,UniProt,B2SU53,GenBank,ACD58243,,,PXO99A,talE,,,,,,,347,Xanthomonas oryzae,1009853,X11-5A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: biparental conjugation,,,YVS,29864161,PubMed,10.1371/journal.ppat.1007092,PLoS Pathog. 2018 Jun 4;14(6):e1007092,mathildehutin1@gmail.com,Mutation of talB in BAI3 resulted in a decrease of virulence partially complemented by the induction of OsERF#123.,T T Tran 2018,2018,9 genes,Tran-2018-Functional analysis of African Xanth,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11574,PHI:8172,,no data found,,,,,,talF,,,,,,,347,Xanthomonas oryzae,1009853,X11-5A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: biparental conjugation,,,YVS,29864161,PubMed,10.1371/journal.ppat.1007092,PLoS Pathog. 2018 Jun 4;14(6):e1007092,mathildehutin1@gmail.com,Mutation of talB in BAI3 resulted in a decrease of virulence partially complemented by the induction of OsERF#123.,T T Tran 2018,2018,9 genes,Tran-2018-Functional analysis of African Xanth,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11575,PHI:8173,,no data found,,,,,,talG,,,,,,,347,Xanthomonas oryzae,1009853,X11-5A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: biparental conjugation,,,YVS,29864161,PubMed,10.1371/journal.ppat.1007092,PLoS Pathog. 2018 Jun 4;14(6):e1007092,mathildehutin1@gmail.com,Mutation of talB in BAI3 resulted in a decrease of virulence partially complemented by the induction of OsERF#123.,T T Tran 2018,2018,9 genes,Tran-2018-Functional analysis of African Xanth,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11576,PHI:8174,,no data found,,,,,,talH,,,,,,,347,Xanthomonas oryzae,1009853,X11-5A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: biparental conjugation,,,YVS,29864161,PubMed,10.1371/journal.ppat.1007092,PLoS Pathog. 2018 Jun 4;14(6):e1007092,mathildehutin1@gmail.com,Mutation of talB in BAI3 resulted in a decrease of virulence partially complemented by the induction of OsERF#123.,T T Tran 2018,2018,9 genes,Tran-2018-Functional analysis of African Xanth,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11577,PHI:8175,,no data found,,,,,,talI,,,,,,,347,Xanthomonas oryzae,1009853,X11-5A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: biparental conjugation,,,YVS,29864161,PubMed,10.1371/journal.ppat.1007092,PLoS Pathog. 2018 Jun 4;14(6):e1007092,mathildehutin1@gmail.com,Mutation of talB in BAI3 resulted in a decrease of virulence partially complemented by the induction of OsERF#123.,T T Tran 2018,2018,9 genes,Tran-2018-Functional analysis of African Xanth,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11578,PHI:8168,UniProt,G7TEI1,GenBank,AEQ95160,,,BLS256,talB,,,,,,,347,Xanthomonas oryzae,,BAI3,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),Azucena landrace,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29864161,PubMed,10.1371/journal.ppat.1007092,PLoS Pathog. 2018 Jun 4;14(6):e1007092,mathildehutin1@gmail.com,Mutation of talB in BAI3 resulted in a decrease of virulence partially complemented by the induction of OsERF#123.,T T Tran 2018,2018,9 genes,Tran-2018-Functional analysis of African Xanth,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11579,PHI:8176,UniProt,J9VNE8,GenBank,AFR95982,,,H99,mar1 (CNAG_06695),chromosome 7,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,macrophage activating regulator of cell wall,,,,reduced virulence,,,,,,,,wild type,,no,calcofluor white; Congo red; sodium dodecyl sulfate; caffeine; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29864141,PubMed,10.1371/journal.ppat.1007126,PLoS Pathog. 2018 Jun 4;14(6):e1007126,andrew.alspaugh@duke.edu,"Host gene alteration data available for Card9 and MyD88 adaptor proteins, Dectin-1 and TLR2 pattern recognition receptors.",S K Esher 2018,2018,2 genes,Esher-2018-Defects in intracellular traffickin,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11580,PHI:8176,UniProt,J9VNE8,GenBank,AFR95982,,,H99,mar1 (CNAG_06695),chromosome 7,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,macrophage activating regulator of cell wall,,,,loss of pathogenicity,,,,,,,,wild type,,no,calcofluor white; Congo red; sodium dodecyl sulfate; caffeine; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29864141,PubMed,10.1371/journal.ppat.1007126,PLoS Pathog. 2018 Jun 4;14(6):e1007126,andrew.alspaugh@duke.edu,"Host gene alteration data available for Card9 and MyD88 adaptor proteins, Dectin-1 and TLR2 pattern recognition receptors.",S K Esher 2018,2018,2 genes,Esher-2018-Defects in intracellular traffickin,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11581,PHI:8176,UniProt,J9VNE8,GenBank,AFR95982,,,H99,mar1 (CNAG_06695),chromosome 7,,,,,PHI:8177,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,macrophage activating regulator of cell wall,,,,reduced virulence,,,,,,,,wild type,,no,calcofluor white; Congo red; sodium dodecyl sulfate; caffeine; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29864141,PubMed,10.1371/journal.ppat.1007126,PLoS Pathog. 2018 Jun 4;14(6):e1007126,andrew.alspaugh@duke.edu,"Host gene alteration data available for Card9 and MyD88 adaptor proteins, Dectin-1 and TLR2 pattern recognition receptors.",S K Esher 2018,2018,2 genes,Esher-2018-Defects in intracellular traffickin,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11582,PHI:8177,UniProt,E0XG07,GenBank,ADM26138,,,H99,cap59,,,,,,PHI:8176,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,capsular-associated protein,,,capsule biosynthesis,reduced virulence,,,,,,,,,,no,calcofluor white; Congo red; sodium dodecyl sulfate; caffeine; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29864141,PubMed,10.1371/journal.ppat.1007126,PLoS Pathog. 2018 Jun 4;14(6):e1007126,andrew.alspaugh@duke.edu,"Host gene alteration data available for Card9 and MyD88 adaptor proteins, Dectin-1 and TLR2 pattern recognition receptors.",S K Esher 2018,2018,2 genes,Esher-2018-Defects in intracellular traffickin,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11583,PHI:8178,UniProt,J5JZ53,GenBank,EJP67416,,,ARSEF 2860,Bbgas3,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,,,,,,,,wild type,no,Congo red; calcofluor white; sorbitol; H2O2; menadione,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,29802184,PubMed,10.1128/AEM.01086-18,Appl Environ Microbiol. 2018 May 25. pii: AEM.01086-18,keyhani@ufl.edu,"Loss of Bbgas3 resulted in a unique decreased ability to grow at high pH, with little to no effects seen with respect to other stress conditions.",Z Luo 2018,2018,1 gene,Luo-2018-The Bbgas3 beta-glucanosyltransferase,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11584,PHI:8178,UniProt,J5JZ53,GenBank,EJP67416,,,ARSEF 2860,Bbgas3,,,,,,,176275,Beauveria bassiana,,ATCC 90517,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"beta-1,3-glucanosyltransferase",,,,unaffected pathogenicity,,,,,,,,,wild type,no,Congo red; calcofluor white; sorbitol; H2O2; menadione,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,29802184,PubMed,10.1128/AEM.01086-18,Appl Environ Microbiol. 2018 May 25. pii: AEM.01086-18,keyhani@ufl.edu,"Loss of Bbgas3 resulted in a unique decreased ability to grow at high pH, with little to no effects seen with respect to other stress conditions.",Z Luo 2018,2018,1 gene,Luo-2018-The Bbgas3 beta-glucanosyltransferase,BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11585,PHI:8179,UniProt,G4NAY4,GenBank,EHA48746,,,70-15,MoSsb1 (MGG_11513),chromosome 5,,,MoSsz1; MoZuo1,UniProt: G4NLU9; GenBank: EHA46152; UniProt: G5EH26; GenBank: EHA46643,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,heat shock protein,,,CWI MAP kinase pathway,loss of pathogenicity,yes,,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29869941,PubMed,10.1094/MPMI-02-18-0052-R,Mol Plant Microbe Interact. 2018 Jun 5,zhgzhang@njau.edu.cn,"MoSsb1, in complex with MoSsz1 and MoZuo1, contributed to the growth, conidiation and pathogenicity of the blast fungus, likely by modulating MoMkk1 biosynthesis to impact CWI signaling.",J Yang 2018,2018,3 genes,"Yang-2018-Heat shock proteins MoSsb1, MoSsz1",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11586,PHI:8179,UniProt,G4NAY4,GenBank,EHA48746,,,70-15,MoSsb1 (MGG_11513),chromosome 5,V443F,,MoSsz1; MoZuo1,UniProt: G4NLU9; GenBank: EHA46152; UniProt: G5EH26; GenBank: EHA46643,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,heat shock protein,,,CWI MAP kinase pathway,loss of pathogenicity,yes,,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene mutation; gene complementation,,,YVS,29869941,PubMed,10.1094/MPMI-02-18-0052-R,Mol Plant Microbe Interact. 2018 Jun 5,zhgzhang@njau.edu.cn,"MoSsb1, in complex with MoSsz1 and MoZuo1, contributed to the growth, conidiation and pathogenicity of the blast fungus, likely by modulating MoMkk1 biosynthesis to impact CWI signaling.",J Yang 2018,2018,3 genes,"Yang-2018-Heat shock proteins MoSsb1, MoSsz1",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11587,PHI:8180,UniProt,G5EH26,GenBank,EHA46643,,,70-15,MoZuo1 (MGG_10565),chromosome 7,,,MoSsz1; MoSsb1,UniProt: G4NLU9; GenBank: EHA46152; UniProt: G4NAY4; GenBank: EHA48746,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,heat shock protein,,,CWI MAP kinase pathway,loss of pathogenicity,yes,,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29869941,PubMed,10.1094/MPMI-02-18-0052-R,Mol Plant Microbe Interact. 2018 Jun 5,zhgzhang@njau.edu.cn,"MoSsb1, in complex with MoSsz1 and MoZuo1, contributed to the growth, conidiation and pathogenicity of the blast fungus, likely by modulating MoMkk1 biosynthesis to impact CWI signaling.",J Yang 2018,2018,3 genes,"Yang-2018-Heat shock proteins MoSsb1, MoSsz1",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11588,PHI:8181,UniProt,G4NLU9,GenBank,EHA46152,,,70-15,MoSsz1 (MGG_02842),chromosome 7,,,MoSsb1; MoZuo1,UniProt: G4NAY4; GenBank: EHA48746; UniProt: G5EH26; GenBank: EHA46643,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,heat shock protein,,,CWI MAP kinase pathway,loss of pathogenicity,yes,,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29869941,PubMed,10.1094/MPMI-02-18-0052-R,Mol Plant Microbe Interact. 2018 Jun 5,zhgzhang@njau.edu.cn,"MoSsb1, in complex with MoSsz1 and MoZuo1, contributed to the growth, conidiation and pathogenicity of the blast fungus, likely by modulating MoMkk1 biosynthesis to impact CWI signaling.",J Yang 2018,2018,3 genes,"Yang-2018-Heat shock proteins MoSsb1, MoSsz1",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11589,PHI:8179,UniProt,G4NAY4,GenBank,EHA48746,,,70-15,MoSsb1 (MGG_11513),chromosome 5,,,MoSsz1; MoZuo1,UniProt: G4NLU9; GenBank: EHA46152; UniProt: G5EH26; GenBank: EHA46643,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,heat shock protein,,,CWI MAP kinase pathway,loss of pathogenicity,yes,,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29869941,PubMed,10.1094/MPMI-02-18-0052-R,Mol Plant Microbe Interact. 2018 Jun 5,zhgzhang@njau.edu.cn,"MoSsb1, in complex with MoSsz1 and MoZuo1, contributed to the growth, conidiation and pathogenicity of the blast fungus, likely by modulating MoMkk1 biosynthesis to impact CWI signaling.",J Yang 2018,2018,3 genes,"Yang-2018-Heat shock proteins MoSsb1, MoSsz1",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11590,PHI:8180,UniProt,G5EH26,GenBank,EHA46643,,,70-15,MoZuo1 (MGG_10565),chromosome 7,,,MoSsz1; MoSsb1,UniProt: G4NLU9; GenBank: EHA46152; UniProt: G4NAY4; GenBank: EHA48746,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,heat shock protein,,,CWI MAP kinase pathway,loss of pathogenicity,yes,,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29869941,PubMed,10.1094/MPMI-02-18-0052-R,Mol Plant Microbe Interact. 2018 Jun 5,zhgzhang@njau.edu.cn,"MoSsb1, in complex with MoSsz1 and MoZuo1, contributed to the growth, conidiation and pathogenicity of the blast fungus, likely by modulating MoMkk1 biosynthesis to impact CWI signaling.",J Yang 2018,2018,3 genes,"Yang-2018-Heat shock proteins MoSsb1, MoSsz1",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11591,PHI:8181,UniProt,G4NLU9,GenBank,EHA46152,,,70-15,MoSsz1 (MGG_02842),chromosome 7,,,MoSsb1; MoZuo1,UniProt: G4NAY4; GenBank: EHA48746; UniProt: G5EH26; GenBank: EHA46643,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,heat shock protein,,,CWI MAP kinase pathway,loss of pathogenicity,yes,,yes,yes,,reduced,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29869941,PubMed,10.1094/MPMI-02-18-0052-R,Mol Plant Microbe Interact. 2018 Jun 5,zhgzhang@njau.edu.cn,"MoSsb1, in complex with MoSsz1 and MoZuo1, contributed to the growth, conidiation and pathogenicity of the blast fungus, likely by modulating MoMkk1 biosynthesis to impact CWI signaling.",J Yang 2018,2018,3 genes,"Yang-2018-Heat shock proteins MoSsb1, MoSsz1",BATCH_083,2018-06-01,MC,,,,,,,,,,,,,
,,Record 11592,PHI:8182,UniProt,D4GMV8,GenBank,ADD78450,,,LMG 20103,pepM (PANA_3283 ),,,,,,,553,Pantoea ananatis,,OC5a Rpr,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Hendrix,,,bulb; leaf,phosphoenolpyruvate mutase,,,phosphonate biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29953334,PubMed,10.1094/MPMI-04-18-0077-R,Mol Plant Microbe Interact. 2018 Jun 28,svb1@cornell.edu,"Deletion of the pepM gene within this cluster resulted in loss of ability to cause leaf lesions in onions, loss of ability to elicit water-soaking in inoculated onion bulbs, reductions of bacterial growth in onion leaves, and loss of the ability to cause cell death in infiltrated tobacco leaves.",J E Asselin 2018,2018,1 gene,Asselin-2018-Center rot of onion (Allium cepa),BATCH_084AA,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11593,PHI:8183,UniProt,A0A0D1E3D1,GenBank,KIS69025,,,521,Scp2 (UMAG_11938),chromosome 7,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,peroxisomal sterol carrier protein,,,,reduced virulence,,yes,,,,,,wild type,,no,NaCl; sorbitol; calcofluor white; Congo red; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29897130,PubMed,10.1111/nph.15268,New Phytol. 2018 Jun 13,kahmann@mpi-marburg.mpg.de,Scp2 mutants were strongly attenuated in virulence and this defect manifested itself during penetration.,S Krombach 2018,2018,1 gene,Krombach-2018-Virulence function of the Ustila,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11594,PHI:8184,UniProt,Q5F7V4,GenBank,AAW89733,,,FA 1090,SliC (NGO1063),,,,,,,485,Neisseria gonorrhoeae,242231,FA 1090,urogenital tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,vagina,surface-exposed lysozyme inhibitor of c-type lysozyme,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29975784,PubMed,10.1371/journal.ppat.1007081,PLoS Pathog. 2018 Jul 5;14(7):e1007081,Aleksandra.Sikora@oregonstate.edu,"Conserved residues involved in lysozyme inhibition, S83 and K103, were functionally indispensable during infection in wild type mice. vaginal tract",R A Zielke 2018,2018,1 gene,Zielke-2018-SliC is a surface-displayed lipopr,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11595,PHI:8184,UniProt,Q5F7V4,GenBank,AAW89733,,,FA 1090,SliC (NGO1063),,,,,,,485,Neisseria gonorrhoeae,242231,FA 1090,urogenital tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,vagina,surface-exposed lysozyme inhibitor of c-type lysozyme,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: full; gene complementation,,,YVS,29975784,PubMed,10.1371/journal.ppat.1007081,PLoS Pathog. 2018 Jul 5;14(7):e1007081,Aleksandra.Sikora@oregonstate.edu,"Conserved residues involved in lysozyme inhibition, S83 and K103, were functionally indispensable during infection in wild type mice. vaginal tract",R A Zielke 2018,2018,1 gene,Zielke-2018-SliC is a surface-displayed lipopr,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11596,PHI:8185,,no data found,GenBank,XP_011319102,,,PH-1; NRRL 31084,Crz1,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zimai 22,,,spikelet,zinc finger transcription factor,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,NaCl; KCl; Congo red (CR); calcofluor white (CFW); H2O2; LiCl; CaCl2; MgCl2; MnCl2; ZnSO4; carbendazim; tebuconazole; JS399-19,"NaCl: CHEBI:26710; KCl: CHEBI:32588; Congo red (CR): CHEBI:34653; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; LiCl: CHEBI:48607; CaCl2: CHEBI:3312; MgCl2: CHEBI:6636; MnCl2: CHEBI:63041; ZnSO4: CHEBI:35176; carbendazim: CHEBI:3392, CAS:10605-21-7; tebuconazole: CHEBI:81781; JS399-19: CAS:39491-78-6",,,,,gene deletion: full; gene complementation,,,YVS,29947970,PubMed,10.1007/s00294-018-0853-5,Curr Genet. 2018 Jun 8,zhcq@ahau.edu.cn,"Unexpectedly, the deletion mutant was more resistant to osmotic stress and cell wall-damaging agents than the wild-type fungus.",L Chen 2018,2018,1 gene,Chen-2018-The transcription factor FgCrz1A is,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11597,PHI:8185,,no data found,GenBank,XP_011319102,,,PH-1; NRRL 31084,Crz1,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,corn silk,zinc finger transcription factor,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,NaCl; KCl; Congo red (CR); calcofluor white (CFW); H2O2; LiCl; CaCl2; MgCl2; MnCl2; ZnSO4; carbendazim; tebuconazole; JS399-19,"NaCl: CHEBI:26710; KCl: CHEBI:32588; Congo red (CR): CHEBI:34653; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; LiCl: CHEBI:48607; CaCl2: CHEBI:3312; MgCl2: CHEBI:6636; MnCl2: CHEBI:63041; ZnSO4: CHEBI:35176; carbendazim: CHEBI:3392, CAS:10605-21-7; tebuconazole: CHEBI:81781; JS399-19: CAS:39491-78-6",,,,,gene deletion: full; gene complementation,,,YVS,29947970,PubMed,10.1007/s00294-018-0853-5,Curr Genet. 2018 Jun 8,zhcq@ahau.edu.cn,"Unexpectedly, the deletion mutant was more resistant to osmotic stress and cell wall-damaging agents than the wild-type fungus.",L Chen 2018,2018,1 gene,Chen-2018-The transcription factor FgCrz1A is,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11598,PHI:8186,UniProt,Q2G2U9,GenBank,AAL21479,,,,SarA (STM2585),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; thymus,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29924996,PubMed,10.1016/j.celrep.2018.05.072,Cell Rep. 2018 Jun 19;23(12):3525-3536,dennis.ko@duke.edu,ΔSarA showed reduced virulence and reduced p-STAT3 in mice.,S L Jaslow 2018,2018,1 gene,Jaslow-2018-Salmonella Activation of STAT3 Sig,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11599,PHI:8186,UniProt,Q2G2U9,GenBank,AAL21479,,,,SarA (STM2585),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,spleen; liver; cecum,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29924996,PubMed,10.1016/j.celrep.2018.05.072,Cell Rep. 2018 Jun 19;23(12):3525-3536,dennis.ko@duke.edu,ΔSarA showed reduced virulence and reduced p-STAT3 in mice.,S L Jaslow 2018,2018,1 gene,Jaslow-2018-Salmonella Activation of STAT3 Sig,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11600,PHI:8187,UniProt,P10613,GenBank,ACF34636,,,CA95,erg11,chromosome 5,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol 14alpha-demethylase,,,,loss of pathogenicity,,,,,,,,reduced,,no,MnCl2; NaCl; Congo red; SDS; CFW; H2O2,MnCl2: CHEBI:63041; NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29931064,PubMed,10.1093/femsyr/foy057,FEMS Yeast Res. 2018 Nov 1;18(7),ycmzh2012@163.com,C. albicans cells lacking ERG11 were more efficiently killed by macrophages and became avirulent in vivo.,Y Wu 2018,2018,1 gene,Wu-2018-ERG11 couples oxidative stress adaptat,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11601,PHI:8188,UniProt,Q7BLQ1,GenBank,OCJ40122,,,B140/95,virB6a,,,,VirB10,UniProt: P17800; GenBank: AAK90938,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,23013,Kalanchoe daigremontiana (related: devil's backbone),,,,leaf,type IV secretion system protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,YVS,29976757,PubMed,10.1074/jbc.RA118.002751,J Biol Chem. 2018 Jul 5. pii: jbc.RA118.002751,christian.baron@umontreal.ca,"Strains complemented with VirB6aΔ(18-23) and VirB6aΔ(30-35) were avirulent and they did not assemble T-pili, but VirB5 and other VirB proteins and their complexes were stable suggesting that the perturbation of the VirB6-VirB10 interaction explains the phenotype.",C Mary 2018,2018,1 gene,Mary-2018-Interaction via the N terminus of th,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11602,PHI:8188,UniProt,Q7BLQ1,GenBank,OCJ40122,,,B140/95,virB6a,,VirB6aΔ(18-23) and VirB6aΔ(30-35),,VirB10,UniProt: P17800; GenBank: AAK90938,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,23013,Kalanchoe daigremontiana (related: devil's backbone),,,,leaf,type IV secretion system protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,YVS,29976757,PubMed,10.1074/jbc.RA118.002751,J Biol Chem. 2018 Jul 5. pii: jbc.RA118.002751,christian.baron@umontreal.ca,"Strains complemented with VirB6aΔ(18-23) and VirB6aΔ(30-35) were avirulent and they did not assemble T-pili, but VirB5 and other VirB proteins and their complexes were stable suggesting that the perturbation of the VirB6-VirB10 interaction explains the phenotype.",C Mary 2018,2018,1 gene,Mary-2018-Interaction via the N terminus of th,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11603,PHI:8188,UniProt,Q7BLQ1,GenBank,OCJ40122,,,B140/95,virB6a,,VirB6aF20A,,VirB10,UniProt: P17800; GenBank: AAK90938,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,23013,Kalanchoe daigremontiana (related: devil's backbone),,,,leaf,type IV secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,YVS,29976757,PubMed,10.1074/jbc.RA118.002751,J Biol Chem. 2018 Jul 5. pii: jbc.RA118.002751,christian.baron@umontreal.ca,"Strains complemented with VirB6aΔ(18-23) and VirB6aΔ(30-35) were avirulent and they did not assemble T-pili, but VirB5 and other VirB proteins and their complexes were stable suggesting that the perturbation of the VirB6-VirB10 interaction explains the phenotype.",C Mary 2018,2018,1 gene,Mary-2018-Interaction via the N terminus of th,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11604,PHI:8188,UniProt,Q7BLQ1,GenBank,OCJ40122,,,B140/95,virB6a,,VirB6aL18A,,VirB10,UniProt: P17800; GenBank: AAK90938,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,23013,Kalanchoe daigremontiana (related: devil's backbone),,,,leaf,type IV secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: direct injection,,,YVS,29976757,PubMed,10.1074/jbc.RA118.002751,J Biol Chem. 2018 Jul 5. pii: jbc.RA118.002751,christian.baron@umontreal.ca,"Strains complemented with VirB6aΔ(18-23) and VirB6aΔ(30-35) were avirulent and they did not assemble T-pili, but VirB5 and other VirB proteins and their complexes were stable suggesting that the perturbation of the VirB6-VirB10 interaction explains the phenotype.",C Mary 2018,2018,1 gene,Mary-2018-Interaction via the N terminus of th,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11605,PHI:8188,UniProt,Q7BLQ1,GenBank,OCJ40122,,,B140/95,virB6a,,,,VirB10,UniProt: P17800; GenBank: AAK90938,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,4039,Daucus carota (related: carrot),,,,,type IV secretion system protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,YVS,29976757,PubMed,10.1074/jbc.RA118.002751,J Biol Chem. 2018 Jul 5. pii: jbc.RA118.002751,christian.baron@umontreal.ca,"Strains complemented with VirB6aΔ(18-23) and VirB6aΔ(30-35) were avirulent and they did not assemble T-pili, but VirB5 and other VirB proteins and their complexes were stable suggesting that the perturbation of the VirB6-VirB10 interaction explains the phenotype.",C Mary 2018,2018,1 gene,Mary-2018-Interaction via the N terminus of th,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11606,PHI:8188,UniProt,Q7BLQ1,GenBank,OCJ40122,,,B140/95,virB6a,,VirB6aΔ(18-23) and VirB6aΔ(30-35),,VirB10,UniProt: P17800; GenBank: AAK90938,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,4039,Daucus carota (related: carrot),,,,,type IV secretion system protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,YVS,29976757,PubMed,10.1074/jbc.RA118.002751,J Biol Chem. 2018 Jul 5. pii: jbc.RA118.002751,christian.baron@umontreal.ca,"Strains complemented with VirB6aΔ(18-23) and VirB6aΔ(30-35) were avirulent and they did not assemble T-pili, but VirB5 and other VirB proteins and their complexes were stable suggesting that the perturbation of the VirB6-VirB10 interaction explains the phenotype.",C Mary 2018,2018,1 gene,Mary-2018-Interaction via the N terminus of th,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11607,PHI:8188,UniProt,Q7BLQ1,GenBank,OCJ40122,,,B140/95,virB6a,,VirB6aF20A,,VirB10,UniProt: P17800; GenBank: AAK90938,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,4039,Daucus carota (related: carrot),,,,,type IV secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,YVS,29976757,PubMed,10.1074/jbc.RA118.002751,J Biol Chem. 2018 Jul 5. pii: jbc.RA118.002751,christian.baron@umontreal.ca,"Strains complemented with VirB6aΔ(18-23) and VirB6aΔ(30-35) were avirulent and they did not assemble T-pili, but VirB5 and other VirB proteins and their complexes were stable suggesting that the perturbation of the VirB6-VirB10 interaction explains the phenotype.",C Mary 2018,2018,1 gene,Mary-2018-Interaction via the N terminus of th,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11608,PHI:8188,UniProt,Q7BLQ1,GenBank,OCJ40122,,,B140/95,virB6a,,VirB6aL18A,,VirB10,UniProt: P17800; GenBank: AAK90938,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,4039,Daucus carota (related: carrot),,,,,type IV secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,YVS,29976757,PubMed,10.1074/jbc.RA118.002751,J Biol Chem. 2018 Jul 5. pii: jbc.RA118.002751,christian.baron@umontreal.ca,"Strains complemented with VirB6aΔ(18-23) and VirB6aΔ(30-35) were avirulent and they did not assemble T-pili, but VirB5 and other VirB proteins and their complexes were stable suggesting that the perturbation of the VirB6-VirB10 interaction explains the phenotype.",C Mary 2018,2018,1 gene,Mary-2018-Interaction via the N terminus of th,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11609,PHI:8189,UniProt,Q8E3H1,GenBank,CAD47447,,,NEM316,NDH-2,,,,,,,1311,Streptococcus agalactiae,211110,NEM316,group B streptococcal infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; kidney; spleen,"putative type 2 NADH dehydrogenase, homodimeric flavoprotein",,,,reduced virulence,,,,,,,,,,no,alexidine; caspofungin; closantel; triclabendazole; zafirlukast,alexidine: CHEBI:53661; caspofungin: CHEBI:474180; closantel: CHEBI:77053; triclabendazole: CHEBI:94759; zafirlukast: CHEBI:10100,,,,,gene deletion: full; gene complementation,,,YVS,29970468,PubMed,10.1128/mBio.01034-18,MBio. 2018 Jul 3;9(4). pii: e01034-18,lschurig@illinois.edu,Zafirlukast was identified to successfully inhibit both NDH-2 activity and aerobic respiration in intact cells.,A M Lencina 2018,2018,3 genes,Lencina-2018-Type 2 NADH Dehydrogenase Is the,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11610,PHI:8190,UniProt,Q8E3H1,GenBank,CAD47447,,,NEM316,nox-2,,,,,,,1311,Streptococcus agalactiae,211110,NEM316,group B streptococcal infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; kidney; spleen,"putative type 2 NADH dehydrogenase, homodimeric flavoprotein",,,,reduced virulence,,,,,,,,,,no,alexidine; caspofungin; closantel; triclabendazole; zafirlukast,alexidine: CHEBI:53661; caspofungin: CHEBI:474180; closantel: CHEBI:77053; triclabendazole: CHEBI:94759; zafirlukast: CHEBI:10100,,,,,gene mutation,,,YVS,29970468,PubMed,10.1128/mBio.01034-18,MBio. 2018 Jul 3;9(4). pii: e01034-18,lschurig@illinois.edu,Zafirlukast was identified to successfully inhibit both NDH-2 activity and aerobic respiration in intact cells.,A M Lencina 2018,2018,3 genes,Lencina-2018-Type 2 NADH Dehydrogenase Is the,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11611,PHI:8189,UniProt,Q8E3H1,GenBank,CAD47447,,,NEM316,NDH-2,,,,,,PHI:8190,1311,Streptococcus agalactiae,211110,NEM316,group B streptococcal infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; kidney; spleen,"putative type 2 NADH dehydrogenase, homodimeric flavoprotein",,,,reduced virulence,,,,,,,,,,no,alexidine; caspofungin; closantel; triclabendazole; zafirlukast,alexidine: CHEBI:53661; caspofungin: CHEBI:474180; closantel: CHEBI:77053; triclabendazole: CHEBI:94759; zafirlukast: CHEBI:10100,,,,,gene deletion: full,,,YVS,29970468,PubMed,10.1128/mBio.01034-18,MBio. 2018 Jul 3;9(4). pii: e01034-18,lschurig@illinois.edu,Zafirlukast was identified to successfully inhibit both NDH-2 activity and aerobic respiration in intact cells.,A M Lencina 2018,2018,3 genes,Lencina-2018-Type 2 NADH Dehydrogenase Is the,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11612,PHI:8190,UniProt,Q8E3H1,GenBank,CAD47447,,,NEM316,nox-2,,,,,,PHI:8189,1311,Streptococcus agalactiae,211110,NEM316,group B streptococcal infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; kidney; spleen,"putative type 2 NADH dehydrogenase, homodimeric flavoprotein",,,,reduced virulence,,,,,,,,,,no,alexidine; caspofungin; closantel; triclabendazole; zafirlukast,alexidine: CHEBI:53661; caspofungin: CHEBI:474180; closantel: CHEBI:77053; triclabendazole: CHEBI:94759; zafirlukast: CHEBI:10100,,,,,gene mutation,,,YVS,29970468,PubMed,10.1128/mBio.01034-18,MBio. 2018 Jul 3;9(4). pii: e01034-18,lschurig@illinois.edu,Zafirlukast was identified to successfully inhibit both NDH-2 activity and aerobic respiration in intact cells.,A M Lencina 2018,2018,3 genes,Lencina-2018-Type 2 NADH Dehydrogenase Is the,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11613,PHI:8191,UniProt,E7S2J9,GenBank,EFV97951,,,NEM316,cydA,,,,,,,1311,Streptococcus agalactiae,211110,NEM316,group B streptococcal infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; kidney; spleen; liver,cytochrome oxygen reductase,,,,reduced virulence,,,,,,,,,,no,alexidine; caspofungin; closantel; triclabendazole; zafirlukast,alexidine: CHEBI:53661; caspofungin: CHEBI:474180; closantel: CHEBI:77053; triclabendazole: CHEBI:94759; zafirlukast: CHEBI:10100,,,,,gene mutation,,,YVS,29970468,PubMed,10.1128/mBio.01034-18,MBio. 2018 Jul 3;9(4). pii: e01034-18,lschurig@illinois.edu,Zafirlukast was identified to successfully inhibit both NDH-2 activity and aerobic respiration in intact cells.,A M Lencina 2018,2018,3 genes,Lencina-2018-Type 2 NADH Dehydrogenase Is the,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11614,PHI:8192,,no data found,GenBank,ETR92119,,,CI79,trxA,,,,,,,470,Acinetobacter baumannii,1343074,CI79,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,gastrointestinal tract,thioredoxin A,,,,reduced virulence,,,,,,,,aberrant,,no,dithionitrobenzoic acid (DTNB); 1-methylpropyl-2-mercaptoimidazolyl disulfide,dithionitrobenzoic acid: CHEBI:86228; 1-methylpropyl-2-mercaptoimidazolyl disulfide: CAS:141400-58-0,,,,,gene deletion: full; gene complementation,,,YVS,29991584,PubMed,10.1128/mBio.01298-18,MBio. 2018 Jul 10;9(4). pii: e01298-18,bernard.arulanandam@utsa.edu,"SIgA appeared to enhance A. baumannii GI tract colonization, in a process mediated by bacterial thioredoxin A (TrxA), as evidenced by reduction of bacterial attachment in the presence of TrxA inhibitors. Host gene alteration data available for IgA.",P M Ketter 2018,2018,1 gene,Ketter-2018-Acinetobacter baumannii Gastrointe,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11615,PHI:8193,UniProt,V4Z7A0,GenBank,ESS31238,,,VEG,GRA15,,,,,,,5811,Toxoplasma gondii,507601,GT1,toxoplasmosis,rodents,10036,Mesocricetus auratus (related: golden hamster),BHK-21 cell line,,,BHK-21 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,29916065,PubMed,10.1007/s00436-018-5966-8,Parasitol Res. 2018 Jun 19,hejunjun617@163.com,"GRA15II induced upregulation of c-Myc in BHK-21 cells, suggesting that upregulation of c-Myc is a potential mechanism by which GRA15II inhibited apoptosis of infected host cells.",Q Liu 2018,2018,1 gene,Liu-2018-Transcriptomic analysis reveals Toxop,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11616,PHI:8194,UniProt,Q6X972,GenBank,AAP80140,,,BEN 2908,IbeA,,IbeAΔ(229-342),,,,,562,Escherichia coli,,E44,neonatal meningitis,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,invasion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29895952,PubMed,10.1038/s41467-018-04637-3,Nat Commun. 2018 Jun 12;9(1):2296,yhchen@cmu.edu.cn,Host gene alteration data available for Caspr1. 229-342 Domain of E. coli IbeA interacted with the 203-355 domain of endothelial Caspr1 to promote E.coli invasion into brain endothelial cells.,W D Zhao 2018,2018,1 gene,Zhao-2018-Caspr1 is a host receptor for mening,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11617,PHI:8194,UniProt,Q6X972,GenBank,AAP80140,,,BEN 2908,IbeA,,,,,,,562,Escherichia coli,,E44,neonatal meningitis,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,invasion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29895952,PubMed,10.1038/s41467-018-04637-3,Nat Commun. 2018 Jun 12;9(1):2296,yhchen@cmu.edu.cn,Host gene alteration data available for Caspr1. 229-342 Domain of E. coli IbeA interacted with the 203-355 domain of endothelial Caspr1 to promote E.coli invasion into brain endothelial cells.,W D Zhao 2018,2018,1 gene,Zhao-2018-Caspr1 is a host receptor for mening,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11618,PHI:8195,UniProt,Q5A6L6,GenBank,AOW31183,,,SC5314,CaGPI2,chromosome R,,,CaRas1,UniProt: P0CY32; GenBank: AF177670_1,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),MH-S cell line,,,alveolar macrophage,phosphatidylinositol N-acetylglucosaminyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29907567,PubMed,10.1074/jbc.RA117.001225,J Biol Chem. 2018 Jun 15. pii: jbc.RA117.001225,sskomath@mail.jnu.ac.in,The Cagpi2 mutant was more susceptible to macrophage-mediated killing. murine alveolar macrophage cell line,P Jain 2018,2018,1 gene,Jain-2018-Ras signaling activates glycosylphos,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11619,PHI:8196,UniProt,A0A2K1SX57,GenBank,WP_012027976,,,,sbp1,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"srtBCD-associated protein, adhesion-associated factor",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29886087,PubMed,10.1016/j.micpath.2018.06.008,Microb Pathog. 2018 Jun 8;122:90-97,vszw@njau.edu.cn,"SBP1 did not influence the invasion, phagocytosis or intracellular survival of SS2.",Y Qian 2018,2018,1 gene,Qian-2018-SBP1 is an adhesion-associated facto,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11620,PHI:8196,UniProt,A0A2K1SX57,GenBank,WP_012027976,,,,sbp1,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,"srtBCD-associated protein, adhesion-associated factor",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29886087,PubMed,10.1016/j.micpath.2018.06.008,Microb Pathog. 2018 Jun 8;122:90-97,vszw@njau.edu.cn,"SBP1 did not influence the invasion, phagocytosis or intracellular survival of SS2.",Y Qian 2018,2018,1 gene,Qian-2018-SBP1 is an adhesion-associated facto,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11621,PHI:8197,UniProt,A4VUV7,GenBank,ABP89896,,,05ZYH33,tstS (SSU05_0930),,,,,,,1307,Streptococcus suis,,05ZY,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29973920,PubMed,10.3389/fmicb.2018.01309,Front Microbiol. 2018 Jun 19;9:1309,jml8328@126.com,Lack of TstS increased the vulnerability of S.suis to being killed by the PMNs.,Z Xu 2018,2018,1 gene,Xu-2018-Streptococcus suis 2 Transcriptional R,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11622,PHI:8198,UniProt,D0ZAH9,GenBank,ACY83138,,,EIB202,fucP,,,,,,,636,Edwardsiella tarda,498217,EIB202,edwardsiellosis,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,intestine; kidney; spleen,L-fucose permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29886137,PubMed,10.1016/j.fsi.2018.06.011,Fish Shellfish Immunol. 2018 Sep;80:624-630,xpwang@sdau.edu.cn,FucP mutant strain significantly increased LD50 in zebrafish and significantly decreased penetration and motility in mucin than the wild-type strain and tilapia infected with mutant strain show significantly reduced E. tarda adherence and colonization than those infected with the wild-type strain.,J Wu 2018,2018,1 gene,Wu-2018-The role of regulator FucP in Edwardsi,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11623,PHI:8198,UniProt,D0ZAH9,GenBank,ACY83138,,,EIB202,fucP,,,,,,,636,Edwardsiella tarda,498217,EIB202,edwardsiellosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,intestine; kidney; spleen,L-fucose permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29886137,PubMed,10.1016/j.fsi.2018.06.011,Fish Shellfish Immunol. 2018 Sep;80:624-630,xpwang@sdau.edu.cn,FucP mutant strain significantly increased LD50 in zebrafish and significantly decreased penetration and motility in mucin than the wild-type strain and tilapia infected with mutant strain show significantly reduced E. tarda adherence and colonization than those infected with the wild-type strain.,J Wu 2018,2018,1 gene,Wu-2018-The role of regulator FucP in Edwardsi,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11624,PHI:8199,,no data found,GenBank,ACJ42100,,,AB0057,MltB,,,,,,,470,Acinetobacter baumannii,,AB0057Km,pneumonia,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,spleen; kidney; liver; lung,lytic transglycosylase,,,,reduced virulence,,,,,,,,,,no,H2O2; HCl; NaCl,H2O2: CHEBI:16240; HCl: CHEBI:17883; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29884996,PubMed,10.1111/mmi.14000,Mol Microbiol. 2018 Jun 8,hmobley@umich.edu,"Inactivation of mltB not only impaired resistance to serum complement, cationic antimicrobial peptides and oxygen species, but also altered the cell envelope integrity, activated the envelope stress response, drastically reduced the number of pili at the cell surface and finally, significantly decreased colonization of both the bloodstream and the respiratory tract.",S Crépin 2018,2018,1 gene,Crepin-2018-The lytic transglycosylase MltB co,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11625,PHI:8200,UniProt,G5EHI7,GenBank,ACQ73206,,,70-15,BAS1,chromosome IV,,,,,,318829,Magnaporthe oryzae,,95234I-1b,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,biotrophy-associated secreted protein,,,,increased virulence (hypervirulence),,no,,,,reduced,,,reduced,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29931642,PubMed,10.1007/s11356-018-2532-y,Environ Sci Pollut Res Int. 2018 Jun 21,zhongdianshiyansh@163.com,"SA and pH affected morphological development of the BAS1-overexpression blast strain, but had little influence on the pathogenicity of the strain, indicating that BAS1-overexpression may have enhanced the tolerance of this rice blast strain to abiotic stressors.",J Yang 2018,2018,1 gene,Yang-2018-Effects of exogenous salicylic acid,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11626,PHI:8201,UniProt,Q3YJR5,GenBank,ADH04593,,,RH,ROP16,,,,,,,5811,Toxoplasma gondii,,type Chinese 1 strain WH3,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; placenta,rhoptry protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29910815,PubMed,10.3389/fimmu.2018.01222,Front Immunol. 2018 Jun 1;9:1222,xyhong1964@163.com,"WH3Δrop16 strain with GRA15II background of T. gondii type Chinese 1 may cause subversion of immune tolerance at the maternal-fetus interface and in systemic immunity, leading to adverse pregnancy outcomes, which is associated with the Th1 and Th17 biased response.",C Wang 2018,2018,1 gene,Wang-2018-Toxoplasma Chinese 1 Strain of WH3De,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11627,PHI:8203,UniProt,D0ZTB2,GenBank,ACY91682,,,14028S,mgtA,,"mgtA Pro 550,551 Ala",,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,magnesium-transporting ATPase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29949242,PubMed,10.1002/mbo3.680,Microbiologyopen. 2018 Jun 27:e00680,eunjinlee@khu.ac.kr,"The Pro550 and Pro551- substituted mgtA gene promoted Salmonella's intramacrophage survival and mouse virulence, suggesting that EF-P mediated translational control of the mgtA gene was required for Salmonella pathogenesis.",E Choi 2018,2018,1 gene,Choi-2018-Elongation factor P controls transla,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11628,PHI:8203,UniProt,D0ZTB2,GenBank,ACY91682,,,14028S,mgtA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,magnesium-transporting ATPase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29949242,PubMed,10.1002/mbo3.680,Microbiologyopen. 2018 Jun 27:e00680,eunjinlee@khu.ac.kr,"The Pro550 and Pro551- substituted mgtA gene promoted Salmonella's intramacrophage survival and mouse virulence, suggesting that EF-P mediated translational control of the mgtA gene was required for Salmonella pathogenesis.",E Choi 2018,2018,1 gene,Choi-2018-Elongation factor P controls transla,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11629,PHI:8204,UniProt,H7C7K8,,,,,,OppA4,,,,,,,139,Borreliella burgdorferi,,5A18NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,oligopeptide ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29921537,PubMed,10.1016/j.ttbdis.2018.06.006,Ticks Tick Borne Dis. 2018 Jul;9(5):1343-1349,xfyang@iupui.edu,OppA4 was not essential for B. burgdorferi to establish infection in mice.,B Zhou 2018,2018,1 gene,Zhou-2018-The oligopeptide ABC transporter Opp,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11630,PHI:8205,UniProt,Q4UTQ8,GenBank,AAY49565,,,8004,hfq,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. sativus (turnip radish),,,leaf,RNA chaperone,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; SDS; NaCl,H2O2: CHEBI:16240; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29901272,PubMed,10.1111/1758-2229.12657,Environ Microbiol Rep. 2018 Jun 14,jltang@gxu.edu.cn,"Hfq knockout significantly reduced Xcc virulence in Chinese radish and showed a severe defect in the production of virulence factors including extracellular enzymes, extracellular polysaccharide, cell motility and stress tolerance.",J L Lai 2018,2018,1 gene,Lai-2018-The RNA chaperone Hfq is important fo,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11631,PHI:8205,UniProt,Q4UTQ8,GenBank,AAY49565,,,8004,hfq,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,RNA chaperone,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; SDS; NaCl,H2O2: CHEBI:16240; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29901272,PubMed,10.1111/1758-2229.12657,Environ Microbiol Rep. 2018 Jun 14,jltang@gxu.edu.cn,"Hfq knockout significantly reduced Xcc virulence in Chinese radish and showed a severe defect in the production of virulence factors including extracellular enzymes, extracellular polysaccharide, cell motility and stress tolerance.",J L Lai 2018,2018,1 gene,Lai-2018-The RNA chaperone Hfq is important fo,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11632,PHI:8206,UniProt,A9T728,GenBank,XP_001774397,,,Gransden 2004,PpHLP,,chimeric TTSS:PpHLP,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Red Mexican,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous gene expression,,,YVS,29973916,PubMed,10.3389/fmicb.2018.01060,Front Microbiol. 2018 Jun 20;9:1060,krzyma@ibb.waw.pl,PpHLP extended by a TTSS signal of HopQ1 promoted P. syringae growth in bean and was recognized by Nicotiana benthamiana immune system.,M Piechocki 2018,2018,1 gene,Piechocki-2018-An Engineered Distant Homolog o,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11633,PHI:8206,UniProt,A9T728,GenBank,XP_001774397,,,Gransden 2004,PpHLP,,chimeric TTSS:PpHLP,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,4100,Nicotiana benthamiana (no common name found),cv. Xanthi-nc,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous gene expression,,,YVS,29973916,PubMed,10.3389/fmicb.2018.01060,Front Microbiol. 2018 Jun 20;9:1060,krzyma@ibb.waw.pl,PpHLP extended by a TTSS signal of HopQ1 promoted P. syringae growth in bean and was recognized by Nicotiana benthamiana immune system.,M Piechocki 2018,2018,1 gene,Piechocki-2018-An Engineered Distant Homolog o,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11634,PHI:8207,UniProt,G7TBV9,GenBank,RBL98065,,,YN03-24,XopK,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29949665,PubMed,10.1111/nph.15287,New Phytol. 2018 Jun 27,zhangjie@im.ac.cn,Mutation of a putative ubiquitin-conjugation enzyme (E2) binding site abolished XopK-induced degradation of OsSERK2 and compromised XopK-dependent virulence.,J Qin 2018,2018,1 gene,Qin-2018-The Xanthomonas effector XopK harbour,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11635,PHI:8207,UniProt,G7TBV9,GenBank,RBL98065,,,YN03-24,XopK,,ΔxopK/XopK-E2BS,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29949665,PubMed,10.1111/nph.15287,New Phytol. 2018 Jun 27,zhangjie@im.ac.cn,Mutation of a putative ubiquitin-conjugation enzyme (E2) binding site abolished XopK-induced degradation of OsSERK2 and compromised XopK-dependent virulence.,J Qin 2018,2018,1 gene,Qin-2018-The Xanthomonas effector XopK harbour,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11636,PHI:8207,UniProt,G7TBV9,GenBank,RBL98065,,,YN03-24,XopK,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,"XopK-expressing Arabidopsis plants were inoculated with a nonpathogenic mutant strain of P.syringae, hrcC- (hypersensitive response and pathogenicity or conserved gene C), which carries a collection of pathogen/microbe-associated molecular patterns (PAMPs) but lacks a functional type III secretion system.",,YVS,29949665,PubMed,10.1111/nph.15287,New Phytol. 2018 Jun 27,zhangjie@im.ac.cn,"Significantly higher levels of hrcC- growth was detected in the XopK-expressing plants than in the WT plants, indicating that XopK expression suppressed plant resistance against bacterial pathogens.",J Qin 2018,2018,1 gene,Qin-2018-The Xanthomonas effector XopK harbour,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11637,PHI:8208,UniProt,T0JUP9,,,,,Cg-14,BAS2,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),cv. 73-3-97,,,leaf,biotrophy-associated secreted protein,,,,reduced virulence,,,yes,,,reduced,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29941774,PubMed,10.3390/ijms19071860,Int J Mol Sci. 2018 Jun 25;19(7). pii: E1860,czhe@hainu.edu.cn,"The results showed that when inoculated on the wounds of leaves, both WT and ΔBAS2 caused 100% incidence of disease, but when inoculated on nonwounded leaves, the incidence of ΔBAS2-caused disease decreased sharply compared with WT, suggesting that BAS2 was important for the penetration process of pathogen to host.",B An 2018,2018,1 gene,An-2018-BAS2 Is Required for Conidiation and P,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11638,PHI:8209,UniProt,A0QRY7,GenBank,ABK75566,,,MC2 155,MSMEG_1285,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,tetratricopeptide repeat family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,recombinant Mycobacterium smegmatis producing heparin-binding haemagglutinin (HBHA) from M.tuberculosis was used,,YVS,29874861,PubMed,10.3390/ijms19061673,Int J Mol Sci. 2018 Jun 5;19(6). pii: E1673,camille.locht@pasteur-lille.fr,The lack of MSMEG_1285 abolished the clumping phenotype and rough colony morphology of the recombinant M.smegmatis producing HBHA from M. tuberculosis and reduced its adherence to A549 epithelial cells.,R Veyron-Churlet 2018,2018,1 gene,Veyron-Churlet-2018-Rv0613c_MSMEG_1285 Interac,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11639,PHI:8210,UniProt,Q673U2,GenBank,AAT02421,,,,dipeptidylpeptidase IV (DPPIV),,,,,,,1307,Streptococcus suis,,31533,meningitis,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,dipeptidylpeptidase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,29913265,PubMed,10.1016/j.micpath.2018.06.029,Microb Pathog. 2018 Jun 15. pii: S0882-4010(17)31471-7,Daniel.Grenier@greb.ulaval.ca,Pre-incubation of PR-39 with recombinant DPPIV prior to stimulate the microvascular endothelial cells abolished the increased secretion of IL-8 thereby preventing bacterial killing.,G LeBel 2018,2018,1 gene,LeBel-2018-Dipeptidylpeptidase IV of Streptoco,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11640,PHI:8211,UniProt,I1RAX2,GenBank,CEF72640,,,PH-1,FgPex13 (FGSG_00666),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,flower; leaf,docking machinery component,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,,,,,no,H2O2; SDS; Congo red; paraquat,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29901274,PubMed,10.1111/1462-2920.14291,Environ Microbiol. 2018 Jun 14,chenyun0927@zju.edu.cn,Mutants of the docking peroxin exhibited increased sensitivity toward host oxidative bursts and cell wall integrity stress agents and reduced virulence on host plants and FgPex14 was required for pexophagy in F. graminearum.,Y Chen 2018,2018,3 genes,Chen-2018-Contribution of peroxisomal docking,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11641,PHI:8212,UniProt,I1RY32,GenBank,CEF84224,,,PH-1,FgPex14 (FGSG_09263),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,flower; leaf,docking machinery component,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,,,,,no,H2O2; SDS; Congo red; paraquat,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29901274,PubMed,10.1111/1462-2920.14291,Environ Microbiol. 2018 Jun 14,chenyun0927@zju.edu.cn,Mutants of the docking peroxin exhibited increased sensitivity toward host oxidative bursts and cell wall integrity stress agents and reduced virulence on host plants and FgPex14 was required for pexophagy in F. graminearum.,Y Chen 2018,2018,3 genes,Chen-2018-Contribution of peroxisomal docking,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11642,PHI:8211,UniProt,I1RAX2,GenBank,CEF72640,,,PH-1,FgPex13 (FGSG_00666),chromosome 1,,,,,PHI:8212,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,flower; leaf,docking machinery component,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,,,,,no,H2O2; SDS; Congo red; paraquat,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29901274,PubMed,10.1111/1462-2920.14291,Environ Microbiol. 2018 Jun 14,chenyun0927@zju.edu.cn,Mutants of the docking peroxin exhibited increased sensitivity toward host oxidative bursts and cell wall integrity stress agents and reduced virulence on host plants and FgPex14 was required for pexophagy in F. graminearum.,Y Chen 2018,2018,3 genes,Chen-2018-Contribution of peroxisomal docking,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11643,PHI:8212,UniProt,I1RY32,GenBank,CEF84224,,,PH-1,FgPex14 (FGSG_09263),chromosome 4,,,,,PHI:8211,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,flower; leaf,docking machinery component,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,,,,,no,H2O2; SDS; Congo red; paraquat,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29901274,PubMed,10.1111/1462-2920.14291,Environ Microbiol. 2018 Jun 14,chenyun0927@zju.edu.cn,Mutants of the docking peroxin exhibited increased sensitivity toward host oxidative bursts and cell wall integrity stress agents and reduced virulence on host plants and FgPex14 was required for pexophagy in F. graminearum.,Y Chen 2018,2018,3 genes,Chen-2018-Contribution of peroxisomal docking,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11644,PHI:8213,UniProt,I1RKC9,GenBank,CEF79311,,,PH-1,FgPex33 (FGSG_04329),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,flower; leaf,docking machinery component and filamentous fungal specific peroxin,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,,,,,no,H2O2; SDS; Congo red; paraquat,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29901274,PubMed,10.1111/1462-2920.14291,Environ Microbiol. 2018 Jun 14,chenyun0927@zju.edu.cn,Mutants of the docking peroxin exhibited increased sensitivity toward host oxidative bursts and cell wall integrity stress agents and reduced virulence on host plants and FgPex14 was required for pexophagy in F. graminearum.,Y Chen 2018,2018,3 genes,Chen-2018-Contribution of peroxisomal docking,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11645,PHI:8211,UniProt,I1RAX2,GenBank,CEF72640,,,PH-1,FgPex13 (FGSG_00666),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),,,,flower,docking machinery component,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,,,,,no,H2O2; SDS; Congo red; paraquat,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29901274,PubMed,10.1111/1462-2920.14291,Environ Microbiol. 2018 Jun 14,chenyun0927@zju.edu.cn,Mutants of the docking peroxin exhibited increased sensitivity toward host oxidative bursts and cell wall integrity stress agents and reduced virulence on host plants and FgPex14 was required for pexophagy in F. graminearum.,Y Chen 2018,2018,3 genes,Chen-2018-Contribution of peroxisomal docking,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11646,PHI:8212,UniProt,I1RY32,GenBank,CEF84224,,,PH-1,FgPex14 (FGSG_09263),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),,,,flower,docking machinery component,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,,,,,no,H2O2; SDS; Congo red; paraquat,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29901274,PubMed,10.1111/1462-2920.14291,Environ Microbiol. 2018 Jun 14,chenyun0927@zju.edu.cn,Mutants of the docking peroxin exhibited increased sensitivity toward host oxidative bursts and cell wall integrity stress agents and reduced virulence on host plants and FgPex14 was required for pexophagy in F. graminearum.,Y Chen 2018,2018,3 genes,Chen-2018-Contribution of peroxisomal docking,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11647,PHI:8211,UniProt,I1RAX2,GenBank,CEF72640,,,PH-1,FgPex13 (FGSG_00666),chromosome 1,,,,,PHI:8212,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),,,,flower,docking machinery component,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,,,,,no,H2O2; SDS; Congo red; paraquat,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29901274,PubMed,10.1111/1462-2920.14291,Environ Microbiol. 2018 Jun 14,chenyun0927@zju.edu.cn,Mutants of the docking peroxin exhibited increased sensitivity toward host oxidative bursts and cell wall integrity stress agents and reduced virulence on host plants and FgPex14 was required for pexophagy in F. graminearum.,Y Chen 2018,2018,3 genes,Chen-2018-Contribution of peroxisomal docking,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11648,PHI:8212,UniProt,I1RY32,GenBank,CEF84224,,,PH-1,FgPex14 (FGSG_09263),chromosome 4,,,,,PHI:8211,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),,,,flower,docking machinery component,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,,,,,no,H2O2; SDS; Congo red; paraquat,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29901274,PubMed,10.1111/1462-2920.14291,Environ Microbiol. 2018 Jun 14,chenyun0927@zju.edu.cn,Mutants of the docking peroxin exhibited increased sensitivity toward host oxidative bursts and cell wall integrity stress agents and reduced virulence on host plants and FgPex14 was required for pexophagy in F. graminearum.,Y Chen 2018,2018,3 genes,Chen-2018-Contribution of peroxisomal docking,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11649,PHI:8213,UniProt,I1RKC9,GenBank,CEF79311,,,PH-1,FgPex33 (FGSG_04329),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),,,,flower,docking machinery component and filamentous fungal specific peroxin,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,,,,,no,H2O2; SDS; Congo red; paraquat,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29901274,PubMed,10.1111/1462-2920.14291,Environ Microbiol. 2018 Jun 14,chenyun0927@zju.edu.cn,Mutants of the docking peroxin exhibited increased sensitivity toward host oxidative bursts and cell wall integrity stress agents and reduced virulence on host plants and FgPex14 was required for pexophagy in F. graminearum.,Y Chen 2018,2018,3 genes,Chen-2018-Contribution of peroxisomal docking,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11650,PHI:8214,UniProt,Q79GN7,GenBank,CAE42588,,,Tohama I,vag8,,,,,,,520,Bordetella pertussis,743277,B1917,pertussis,primates,9606,Homo sapiens (related: human),,,,blood,complement evasion molecule,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29915576,PubMed,10.3389/fimmu.2018.01172,Front Immunol. 2018 Jun 4;9:1172,i.jongerius@sanquin.nl,Vag8 enhanced contact system activity by binding C1-INH and attenuating its inhibitory function and a Vag8 knockout B. pertussis strain was unable to activate the contact system.,E S Hovingh 2018,2018,1 gene,Hovingh-2018-Virulence Associated Gene 8 of Bo,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11651,PHI:8215,UniProt,Q4QE27,GenBank,XP_001682421,,,Friedlin,PP5,chromosome 18,,,,,,5664,Leishmania major,,MHOM/JL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,protein phosphatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29982859,PubMed,10.1007/s00436-018-5994-4,Parasitol Res. 2018 Jul 8,miguel.morales@nd.edu,"The resulting attenuated virulence of ΔPP5 parasites in the murine model was likely due to defects in the ability of these parasites to cope with stress, with reference to not only potential MAPK pathway alterations but also, more importantly, the efficacy of the HSP83 chaperone machinery.",B Norris-Mullins 2018,2018,1 gene,Norris-Mullins-2018-Leishmania phosphatase PP5,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11652,PHI:8216,UniProt,H9L455,GenBank,AAL22615,,,LT2,MisL,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,autotransporter protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29901711,PubMed,10.1093/femsle/fny142,FEMS Microbiol Lett. 2018 Jun 12,yus@shvri.ac.cn,"MisL deletion reduced bacterial adherence and invasion abilities on HeLa cells, but did not affect the bacterial virulence.",S Wang 2018,2018,1 gene,Wang-2018-Autotransporter MisL of Salmonella e,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11653,PHI:8216,UniProt,H9L455,GenBank,AAL22615,,,LT2,MisL,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,autotransporter protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29901711,PubMed,10.1093/femsle/fny142,FEMS Microbiol Lett. 2018 Jun 12,yus@shvri.ac.cn,"MisL deletion reduced bacterial adherence and invasion abilities on HeLa cells, but did not affect the bacterial virulence.",S Wang 2018,2018,1 gene,Wang-2018-Autotransporter MisL of Salmonella e,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11654,PHI:8216,UniProt,H9L455,GenBank,AAL22615,,,LT2,MisL,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,autotransporter protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29901711,PubMed,10.1093/femsle/fny142,FEMS Microbiol Lett. 2018 Jun 12,yus@shvri.ac.cn,Deletion of misL led to significant impairments in adherence to Caco-2 cells but did not affect invasion capacity. human epithelial colorectal adenocarcinoma cells,S Wang 2018,2018,1 gene,Wang-2018-Autotransporter MisL of Salmonella e,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11655,PHI:8217,UniProt,A0A194VSE0,GenBank,KUI66730,,,03-8,Seb1,chromosome 2,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,transcription factor,,,,reduced virulence,,,,,,increased,,reduced,reduced,no,H2O2; SDS; Congo red; NaCl,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29959044,PubMed,10.1016/j.micpath.2018.06.043,Microb Pathog. 2018 Jun 26;123:132-138,huanglili@nwsuaf.edu.cn,VmSeb1 was not involved in the regulation of pectinase genes expression in V. mali.,Y Wu 2018,2018,1 gene,Wu-2018-Transcription factor VmSeb1 is require,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11656,PHI:8218,UniProt,Q8DQF0,GenBank,AAK99514,,,R6,gls24B (spr0710),,,,,,,1313,Streptococcus pneumoniae,171101,R6,pneumococcal infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,nasopharynx,conserved hypothetical protein,,,,reduced virulence,,,,,,,,reduced,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,29978356,PubMed,10.1007/s00248-018-1218-9,Microb Ecol. 2018 Jul 5,mgaliano@isciii.es,The Δgls24B mutant behaved as a poor colonizer in the nasopharynx of mice and showed 20-fold competence impairment.,M J Ferrándiz 2018,2018,1 gene,Ferrandiz-2018-An Uncharacterized Member of th,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11657,PHI:8219,UniProt,G4MSP1,GenBank,EHA55462,,,70-15,MSP1,chromosome 2,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,leaf,secreted protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host,,,YVS,29970347,PubMed,10.1016/j.jprot.2018.04.015,J Proteomics. 2018 Jun 19. pii: S1874-3919(18)30175-1,stkim71@pusan.ac.kr,MSP1 induced PTI responses in rice leaves.,Q Meng 2018,2018,1 gene,Meng-2018-A proteomic insight into the MSP1 an,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11658,PHI:8220,UniProt,I1RED8,,,,,,Fg02025 (FgArb1),,,,FgSte7,UniProt: A0A2H3HC68; GenBank: PCD40705,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet; leaf,ATP-binding cassette (ABC) transporter,,,,loss of pathogenicity,,,,,,reduced,reduced,reduced,,no,calcofluor white (CFW); H2O2; paraquat,calcoflour white: CHEBI:50011; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29932228,PubMed,10.1111/nph.15261,New Phytol. 2018 Jun 22,zhma@zju.edu.cn,"The FgArb1 mutant exhibited dramatically reduced infective growth within wounded host tissues, likely resulting from its increased sensitivity to oxidative stresses, defective cell wall integrity and reduced deoxynivalenol (DON) production.",Y Yin 2018,2018,6 genes,Yin-2018-The ATP-binding protein FgArb1 is ess,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11659,PHI:8220,UniProt,I1RED8,,,,,,Fg02025 (FgArb1),,,,FgSte7,UniProt: A0A2H3HC68; GenBank: PCD40705,,5518,Fusarium graminearum,229533,PH-1,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,corn silk,ATP-binding cassette (ABC) transporter,,,,loss of pathogenicity,,,,,,reduced,reduced,reduced,,no,calcofluor white (CFW); H2O2; paraquat,calcoflour white: CHEBI:50011; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29932228,PubMed,10.1111/nph.15261,New Phytol. 2018 Jun 22,zhma@zju.edu.cn,"The FgArb1 mutant exhibited dramatically reduced infective growth within wounded host tissues, likely resulting from its increased sensitivity to oxidative stresses, defective cell wall integrity and reduced deoxynivalenol (DON) production.",Y Yin 2018,2018,6 genes,Yin-2018-The ATP-binding protein FgArb1 is ess,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11660,PHI:8221,,no data found,,,,,,Fg10911,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet; leaf,ATP-binding cassette (ABC) transporter,,,,reduced virulence,,,,,,,,reduced,,no,calcofluor white (CFW); H2O2; paraquat,calcoflour white: CHEBI:50011; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29932228,PubMed,10.1111/nph.15261,New Phytol. 2018 Jun 22,zhma@zju.edu.cn,"The FgArb1 mutant exhibited dramatically reduced infective growth within wounded host tissues, likely resulting from its increased sensitivity to oxidative stresses, defective cell wall integrity and reduced deoxynivalenol (DON) production.",Y Yin 2018,2018,6 genes,Yin-2018-The ATP-binding protein FgArb1 is ess,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11661,PHI:8222,UniProt,I1RF50,,,,,,Fg02316,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet; leaf,ATP-binding cassette (ABC) transporter,,,,reduced virulence,,,,,,,,reduced,,no,calcofluor white (CFW); H2O2; paraquat,calcoflour white: CHEBI:50011; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29932228,PubMed,10.1111/nph.15261,New Phytol. 2018 Jun 22,zhma@zju.edu.cn,"The FgArb1 mutant exhibited dramatically reduced infective growth within wounded host tissues, likely resulting from its increased sensitivity to oxidative stresses, defective cell wall integrity and reduced deoxynivalenol (DON) production.",Y Yin 2018,2018,6 genes,Yin-2018-The ATP-binding protein FgArb1 is ess,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11662,PHI:8223,UniProt,I1RW71,GenBank,CEF76898,,,PH-1,Fg08532,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet; leaf,ATP-binding cassette (ABC) transporter,,,,reduced virulence,,,,,,,,reduced,,no,calcofluor white (CFW); H2O2; paraquat,calcoflour white: CHEBI:50011; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29932228,PubMed,10.1111/nph.15261,New Phytol. 2018 Jun 22,zhma@zju.edu.cn,"The FgArb1 mutant exhibited dramatically reduced infective growth within wounded host tissues, likely resulting from its increased sensitivity to oxidative stresses, defective cell wall integrity and reduced deoxynivalenol (DON) production.",Y Yin 2018,2018,6 genes,Yin-2018-The ATP-binding protein FgArb1 is ess,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11663,PHI:8224,UniProt,I1S2J9,,,,,,Fg10995,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet; leaf,ATP-binding cassette (ABC) transporter,,,,reduced virulence,,,,,,,,wild type,,no,calcofluor white (CFW); H2O2; paraquat,calcoflour white: CHEBI:50011; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29932228,PubMed,10.1111/nph.15261,New Phytol. 2018 Jun 22,zhma@zju.edu.cn,"The FgArb1 mutant exhibited dramatically reduced infective growth within wounded host tissues, likely resulting from its increased sensitivity to oxidative stresses, defective cell wall integrity and reduced deoxynivalenol (DON) production.",Y Yin 2018,2018,6 genes,Yin-2018-The ATP-binding protein FgArb1 is ess,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11664,PHI:8225,,no data found,,,,,,Fg04580,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet; leaf,ATP-binding cassette (ABC) transporter,,,,reduced virulence,,,,,,,,wild type,,no,calcofluor white (CFW); H2O2; paraquat,calcoflour white: CHEBI:50011; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,29932228,PubMed,10.1111/nph.15261,New Phytol. 2018 Jun 22,zhma@zju.edu.cn,"The FgArb1 mutant exhibited dramatically reduced infective growth within wounded host tissues, likely resulting from its increased sensitivity to oxidative stresses, defective cell wall integrity and reduced deoxynivalenol (DON) production.",Y Yin 2018,2018,6 genes,Yin-2018-The ATP-binding protein FgArb1 is ess,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11665,PHI:8226,UniProt,V5TAI6,GenBank,AHB60824,,,PA10-7858,RtxA,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,moths,7091,Bombyx mori (related: domestic silkworm),,,,hemocoel,alpha-xylosidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29969671,PubMed,10.1016/j.micpath.2018.06.046,Microb Pathog. 2018 Jun 30;123:74-81,watarai@yamaguchi-u.ac.jp,The mutant strain revealed significantly reduced intracellular growth and cellular cytotoxicity in silkworms and THP1 cells compared with its parental strain of F. novicida.,S S Saha 2018,2018,1 gene,Saha-2018-RtxA like protein contributes to inf,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11666,PHI:8226,UniProt,V5TAI6,GenBank,AHB60824,,,PA10-7858,RtxA,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,alpha-xylosidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29969671,PubMed,10.1016/j.micpath.2018.06.046,Microb Pathog. 2018 Jun 30;123:74-81,watarai@yamaguchi-u.ac.jp,The mutant strain revealed significantly reduced intracellular growth and cellular cytotoxicity in silkworms and THP1 cells compared with its parental strain of F. novicida.,S S Saha 2018,2018,1 gene,Saha-2018-RtxA like protein contributes to inf,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11667,PHI:8226,UniProt,V5TAI6,GenBank,AHB60824,,,PA10-7858,RtxA,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,odd-toed ungulates,9796,Equus caballus (related: horse),,,,erythrocyte,alpha-xylosidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29969671,PubMed,10.1016/j.micpath.2018.06.046,Microb Pathog. 2018 Jun 30;123:74-81,watarai@yamaguchi-u.ac.jp,RtxA of F. novicida did not produce hemolysis in horse RBCs,S S Saha 2018,2018,1 gene,Saha-2018-RtxA like protein contributes to inf,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11668,PHI:8227,UniProt,I1RMS6,,,,,,FgBUD3 (FGSG_05273),,,,FgRho4,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bainong 979,,,spikelet; leaf,Rho4-interacting guanine nucleotide exchange factor,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,,no,calcofluor white (CFW); Congo red,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29930543,PubMed,10.3389/fmicb.2018.01209. eCollection 2018,Front Microbiol. 2018 Jun 7;9:1209,zonghuaw@163.com,The deletion of FgBUD3 completely abolished sexual reproduction and triggered the production of abnormal asexual spores with nearly no septum in ΔFgbud3 strain.,C Zhang 2018,2018,1 gene,"Zhang-2018-FgBud3, a Rho4-Interacting Guanine",BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11669,PHI:8228,UniProt,A0Q7H2,GenBank,ABK90187,,,U112,IglE,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,Francisella pathogenicity island protein intracellular growth locus E,,,,reduced virulence,,,,,,,,,,no,potassium chloride,potassium chloride: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,29978561,PubMed,10.1002/mbo3.684,Microbiologyopen. 2018 Jul 5:e00684,watarai@yamaguchi-u.ac.jp,Deleting iglE from Francisella tularensis subsp. novicida (F. novicida) decreased intracellular growth.,T Shimizu 2018,2018,1 gene,Shimizu-2018-Expression of Francisella pathoge,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11670,PHI:8229,UniProt,J5JXF7,GenBank,EJP66961,,,ARSEF 2860,Ste7 (BBA_04254),,ste7S216A/T220A or ste7S362A,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitogen-activated protein kinase (MAPK) kinase,,,,loss of pathogenicity,,,,,,reduced,,reduced,reduced,no,NaCl; KCl; sorbitol; H2O2; menadione,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene mutation; gene complementation,,,YVS,29948113,PubMed,10.1007/s00253-018-9148-5,Appl Microbiol Biotechnol. 2018 Jun 11,mgfeng@zju.edu.cn,"The fungal infection to host through cuticular penetration was abolished by both the loss-of-function mutation of Ste7 and the mutagenesis of S216/T220 or S362 and severely blocked by the mutagenesis of S440, T391 or S485 in B. bassiana.",Z K Wang 2018,2018,1 gene,Wang-2018-C-terminal Ser_Thr residues are vita,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11671,PHI:8229,UniProt,J5JXF7,GenBank,EJP66961,,,ARSEF 2860,Ste7 (BBA_04254),,ste7S391A or ste7S440A or ste7T485A,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitogen-activated protein kinase (MAPK) kinase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl; KCl; sorbitol; H2O2; menadione,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene mutation; gene complementation,,,YVS,29948113,PubMed,10.1007/s00253-018-9148-5,Appl Microbiol Biotechnol. 2018 Jun 11,mgfeng@zju.edu.cn,"The fungal infection to host through cuticular penetration was abolished by both the loss-of-function mutation of Ste7 and the mutagenesis of S216/T220 or S362 and severely blocked by the mutagenesis of S440, T391 or S485 in B. bassiana.",Z K Wang 2018,2018,1 gene,Wang-2018-C-terminal Ser_Thr residues are vita,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11672,PHI:8229,UniProt,J5JXF7,GenBank,EJP66961,,,ARSEF 2860,Ste7 (BBA_04254),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitogen-activated protein kinase (MAPK) kinase,,,,loss of pathogenicity,,,,,,reduced,,reduced,reduced,no,NaCl; KCl; sorbitol; H2O2; menadione,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,29948113,PubMed,10.1007/s00253-018-9148-5,Appl Microbiol Biotechnol. 2018 Jun 11,mgfeng@zju.edu.cn,"The fungal infection to host through cuticular penetration was abolished by both the loss-of-function mutation of Ste7 and the mutagenesis of S216/T220 or S362 and severely blocked by the mutagenesis of S440, T391 or S485 in B. bassiana.",Z K Wang 2018,2018,1 gene,Wang-2018-C-terminal Ser_Thr residues are vita,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11673,PHI:8230,,no data found,,,,,,PcORP1,,G839W,,,,,4784,Phytophthora capsici,,BYA5,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,oxysterol binding protein related protein-1,,,,unaffected pathogenicity,,,,,,,reduced,,,no,,,,,,,gene mutation,,,YVS,29979095,PubMed,10.1094/PHYTO-01-18-0010-R,Phytopathology. 2018 Jul 6,brett.tyler@oregonstate.edu,"Transformants containing heterozygous G770V, G839W mutations and a point mutation in PcORP1, ΔN837 showed high levels of oxathiapiprolin resistance.",J Miao 2018,2018,2 genes,Miao-2018-Mutations in ORP1 conferring oxathia,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11674,PHI:8230,,no data found,,,,,,PcORP1,,G770V,,,,,4784,Phytophthora capsici,,BYA5,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,oxysterol binding protein related protein-1,,,,unaffected pathogenicity,,,,,,,wild type,,,no,,,,,,,gene mutation,,,YVS,29979095,PubMed,10.1094/PHYTO-01-18-0010-R,Phytopathology. 2018 Jul 6,brett.tyler@oregonstate.edu,"Transformants containing heterozygous G770V, G839W mutations and a point mutation in PcORP1, ΔN837 showed high levels of oxathiapiprolin resistance.",J Miao 2018,2018,2 genes,Miao-2018-Mutations in ORP1 conferring oxathia,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11675,PHI:8230,,no data found,,,,,,PcORP1,,N837,,,,,4784,Phytophthora capsici,,BYA5,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,oxysterol binding protein related protein-1,,,,reduced virulence,,,,,,,reduced,,,no,,,,,,,gene mutation,,,YVS,29979095,PubMed,10.1094/PHYTO-01-18-0010-R,Phytopathology. 2018 Jul 6,brett.tyler@oregonstate.edu,"Transformants containing heterozygous G770V, G839W mutations and a point mutation in PcORP1, ΔN837 showed high levels of oxathiapiprolin resistance.",J Miao 2018,2018,2 genes,Miao-2018-Mutations in ORP1 conferring oxathia,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11676,PHI:8231,,no data found,,,,,,PsORP1,,N837,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,oxysterol binding protein related protein-1,,,,reduced virulence,,,,,,,reduced,,,no,,,,,,,gene mutation,,,YVS,29979095,PubMed,10.1094/PHYTO-01-18-0010-R,Phytopathology. 2018 Jul 6,brett.tyler@oregonstate.edu,"Transformants containing heterozygous G770V, G839W mutations and a point mutation in PcORP1, ΔN837 showed high levels of oxathiapiprolin resistance.",J Miao 2018,2018,2 genes,Miao-2018-Mutations in ORP1 conferring oxathia,BATCH_084A,2018-07-01,MC,,,,,,,,,,,,,
,,Record 11677,PHI:8232,UniProt,G5EHM5,GenBank,EHA46010,,,70-15,MoPmt1 (MGG_02954),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,O-mannosyltransferase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29946987,PubMed,10.1007/s00294-018-0864-2,Curr Genet. 2018 Jun 26,kandylemon@163.com,MoPmt4 PMT motif was found to be essential for the full virulence of M. oryzae,Y Pan 2018,2018,3 genes,Pan-2018-Pleiotropic roles of O-mannosyltransf,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11678,PHI:8233,UniProt,G4MTN1,GenBank,EHA55589,,,70-15,MoPmt2 (MGG_07190),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,O-mannosyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29946987,PubMed,10.1007/s00294-018-0864-2,Curr Genet. 2018 Jun 26,kandylemon@163.com,MoPmt4 PMT motif was found to be essential for the full virulence of M. oryzae,Y Pan 2018,2018,3 genes,Pan-2018-Pleiotropic roles of O-mannosyltransf,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11679,PHI:8234,UniProt,G4MZF8,GenBank,EHA53713,,,70-15,MoPmt4 (MGG_04427),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,O-mannosyltransferase,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,aberrant,reduced,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29946987,PubMed,10.1007/s00294-018-0864-2,Curr Genet. 2018 Jun 26,kandylemon@163.com,MoPmt4 PMT motif was found to be essential for the full virulence of M. oryzae,Y Pan 2018,2018,3 genes,Pan-2018-Pleiotropic roles of O-mannosyltransf,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11680,PHI:8234,UniProt,G4MZF8,GenBank,EHA53713,,,70-15,MoPmt4 (MGG_04427),chromosome 2,MoPmt4ΔPMT-GFP,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,O-mannosyltransferase,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,aberrant,reduced,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,29946987,PubMed,10.1007/s00294-018-0864-2,Curr Genet. 2018 Jun 26,kandylemon@163.com,MoPmt4 PMT motif was found to be essential for the full virulence of M. oryzae,Y Pan 2018,2018,3 genes,Pan-2018-Pleiotropic roles of O-mannosyltransf,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11681,PHI:8234,UniProt,G4MZF8,GenBank,EHA53713,,,70-15,MoPmt4 (MGG_04427),chromosome 2,MoPmt4ΔMIR-GFP,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,O-mannosyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,29946987,PubMed,10.1007/s00294-018-0864-2,Curr Genet. 2018 Jun 26,kandylemon@163.com,MoPmt4 PMT motif was found to be essential for the full virulence of M. oryzae,Y Pan 2018,2018,3 genes,Pan-2018-Pleiotropic roles of O-mannosyltransf,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11682,PHI:8232,UniProt,G5EHM5,GenBank,EHA46010,,,70-15,MoPmt1 (MGG_02954),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,O-mannosyltransferase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29946987,PubMed,10.1007/s00294-018-0864-2,Curr Genet. 2018 Jun 26,kandylemon@163.com,MoPmt4 PMT motif was found to be essential for the full virulence of M. oryzae,Y Pan 2018,2018,3 genes,Pan-2018-Pleiotropic roles of O-mannosyltransf,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11683,PHI:8233,UniProt,G4MTN1,GenBank,EHA55589,,,70-15,MoPmt2 (MGG_07190),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,O-mannosyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29946987,PubMed,10.1007/s00294-018-0864-2,Curr Genet. 2018 Jun 26,kandylemon@163.com,MoPmt4 PMT motif was found to be essential for the full virulence of M. oryzae,Y Pan 2018,2018,3 genes,Pan-2018-Pleiotropic roles of O-mannosyltransf,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11684,PHI:8234,UniProt,G4MZF8,GenBank,EHA53713,,,70-15,MoPmt4 (MGG_04427),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,O-mannosyltransferase,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,aberrant,reduced,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29946987,PubMed,10.1007/s00294-018-0864-2,Curr Genet. 2018 Jun 26,kandylemon@163.com,MoPmt4 PMT motif was found to be essential for the full virulence of M. oryzae,Y Pan 2018,2018,3 genes,Pan-2018-Pleiotropic roles of O-mannosyltransf,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11685,PHI:8234,UniProt,G4MZF8,GenBank,EHA53713,,,70-15,MoPmt4 (MGG_04427),chromosome 2,MoPmt4ΔPMT-GFP,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,O-mannosyltransferase,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,aberrant,reduced,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,29946987,PubMed,10.1007/s00294-018-0864-2,Curr Genet. 2018 Jun 26,kandylemon@163.com,MoPmt4 PMT motif was found to be essential for the full virulence of M. oryzae,Y Pan 2018,2018,3 genes,Pan-2018-Pleiotropic roles of O-mannosyltransf,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11686,PHI:8234,UniProt,G4MZF8,GenBank,EHA53713,,,70-15,MoPmt4 (MGG_04427),chromosome 2,MoPmt4ΔMIR-GFP,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,O-mannosyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,29946987,PubMed,10.1007/s00294-018-0864-2,Curr Genet. 2018 Jun 26,kandylemon@163.com,MoPmt4 PMT motif was found to be essential for the full virulence of M. oryzae,Y Pan 2018,2018,3 genes,Pan-2018-Pleiotropic roles of O-mannosyltransf,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11687,PHI:8235,UniProt,Q87AA4,GenBank,AAO29754,,,Temecula1,pilA1 (PD1924),,,,,,,2371,Xylella fastidiosa,,TemeculaL,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,xylem,fimbrial protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29980551,PubMed,10.1128/AEM.01167-18,Appl Environ Microbiol. 2018 Jul 6. pii: AEM.01167-18,lzd0005@auburn.edu,"Deletion of pilA2 caused loss of twitching motility, whereas deletion of pilA1 did not influence twitching motility but caused hyperpiliation and extended distribution of TFP along the sides of the cell. xylem sap",P P Kandel 2018,2018,2 genes,Kandel-2018-A short protocol for gene knockout,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11688,PHI:8236,UniProt,Q87AA2,GenBank,AAO29756,,,Temecula1,pilA2 (PD1926),,,,,,,2371,Xylella fastidiosa,,TemeculaL,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,xylem,fimbrial protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29980551,PubMed,10.1128/AEM.01167-18,Appl Environ Microbiol. 2018 Jul 6. pii: AEM.01167-18,lzd0005@auburn.edu,"Deletion of pilA2 caused loss of twitching motility, whereas deletion of pilA1 did not influence twitching motility but caused hyperpiliation and extended distribution of TFP along the sides of the cell. xylem sap",P P Kandel 2018,2018,2 genes,Kandel-2018-A short protocol for gene knockout,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11689,PHI:8235,UniProt,Q87AA4,GenBank,AAO29754,,,Temecula1,pilA1 (PD1924),,,,,,PHI:8236,2371,Xylella fastidiosa,,TemeculaL,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,xylem,fimbrial protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29980551,PubMed,10.1128/AEM.01167-18,Appl Environ Microbiol. 2018 Jul 6. pii: AEM.01167-18,lzd0005@auburn.edu,"Deletion of pilA2 caused loss of twitching motility, whereas deletion of pilA1 did not influence twitching motility but caused hyperpiliation and extended distribution of TFP along the sides of the cell. xylem sap",P P Kandel 2018,2018,2 genes,Kandel-2018-A short protocol for gene knockout,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11690,PHI:8236,UniProt,Q87AA2,GenBank,AAO29756,,,Temecula1,pilA2 (PD1926),,,,,,PHI:8235,2371,Xylella fastidiosa,,TemeculaL,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,xylem,fimbrial protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29980551,PubMed,10.1128/AEM.01167-18,Appl Environ Microbiol. 2018 Jul 6. pii: AEM.01167-18,lzd0005@auburn.edu,"Deletion of pilA2 caused loss of twitching motility, whereas deletion of pilA1 did not influence twitching motility but caused hyperpiliation and extended distribution of TFP along the sides of the cell. xylem sap",P P Kandel 2018,2018,2 genes,Kandel-2018-A short protocol for gene knockout,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11691,PHI:8235,UniProt,Q87AA4,GenBank,AAO29754,,,Temecula1,pilA1 (PD1924),,,,,,,2371,Xylella fastidiosa,,WM1-1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,xylem,fimbrial protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29980551,PubMed,10.1128/AEM.01167-18,Appl Environ Microbiol. 2018 Jul 6. pii: AEM.01167-18,lzd0005@auburn.edu,"Deletion of pilA2 caused loss of twitching motility, whereas deletion of pilA1 did not influence twitching motility but caused hyperpiliation and extended distribution of TFP along the sides of the cell. xylem sap",P P Kandel 2018,2018,2 genes,Kandel-2018-A short protocol for gene knockout,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11692,PHI:8236,UniProt,Q87AA2,GenBank,AAO29756,,,Temecula1,pilA2 (PD1926),,,,,,,2371,Xylella fastidiosa,,WM1-1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,xylem,fimbrial protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29980551,PubMed,10.1128/AEM.01167-18,Appl Environ Microbiol. 2018 Jul 6. pii: AEM.01167-18,lzd0005@auburn.edu,"Deletion of pilA2 caused loss of twitching motility, whereas deletion of pilA1 did not influence twitching motility but caused hyperpiliation and extended distribution of TFP along the sides of the cell. xylem sap",P P Kandel 2018,2018,2 genes,Kandel-2018-A short protocol for gene knockout,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11693,PHI:8235,UniProt,Q87AA4,GenBank,AAO29754,,,Temecula1,pilA1 (PD1924),,,,,,PHI:8236,2371,Xylella fastidiosa,,WM1-1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,xylem,fimbrial protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29980551,PubMed,10.1128/AEM.01167-18,Appl Environ Microbiol. 2018 Jul 6. pii: AEM.01167-18,lzd0005@auburn.edu,"Deletion of pilA2 caused loss of twitching motility, whereas deletion of pilA1 did not influence twitching motility but caused hyperpiliation and extended distribution of TFP along the sides of the cell. xylem sap",P P Kandel 2018,2018,2 genes,Kandel-2018-A short protocol for gene knockout,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11694,PHI:8236,UniProt,Q87AA2,GenBank,AAO29756,,,Temecula1,pilA2 (PD1926),,,,,,PHI:8235,2371,Xylella fastidiosa,,WM1-1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,xylem,fimbrial protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29980551,PubMed,10.1128/AEM.01167-18,Appl Environ Microbiol. 2018 Jul 6. pii: AEM.01167-18,lzd0005@auburn.edu,"Deletion of pilA2 caused loss of twitching motility, whereas deletion of pilA1 did not influence twitching motility but caused hyperpiliation and extended distribution of TFP along the sides of the cell. xylem sap",P P Kandel 2018,2018,2 genes,Kandel-2018-A short protocol for gene knockout,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11695,PHI:8237,UniProt,Q6XUI3,GenBank,AAO42611,,,,ump2,,,,,,,5270,Ustilago maydis,559306,FB1,smut,monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling,high affinity ammonium transporter,,,,reduced virulence,yes,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29880199,PubMed,10.1016/j.funbio.2018.03.011,Fungal Biol. 2018 Jul;122(7):639-650,mhperl01@louisville.edu,Deletion of ump2 either in both mating partners or in a solopathogenic haploid strain resulted in a dramatic reduction in disease severity for infected plants.,J A Paul 2018,2018,1 gene,Paul-2018-Coordinate regulation of Ustilago ma,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11696,PHI:8238,,no data found,GenBank,ABV52877,,,81116; NCTC 11828,capC (C8J_1278),,,,,,,197,Campylobacter jejuni,407148,81116,gastroenteritis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,autotransporter protein,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,YVS,29915112,PubMed,10.1128/AEM.01032-18,Appl Environ Microbiol. 2018 Aug 1;84(16). pii: e01032-18,jw.mehat@surrey.ac.uk,"C. jejuni capC mutants displayed significantly reduced adherence to and invasion of non-polarized, partially differentiated Caco-2 and T84 intestinal epithelial cells.",J W Mehat 2018,2018,1 gene,"Mehat-2018-Characterisation of CapC, a novel a",BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11697,PHI:8238,,no data found,GenBank,ABV52877,,,81116; NCTC 11828,capC (C8J_1278),,,,,,,197,Campylobacter jejuni,645464,M1,gastroenteritis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,autotransporter protein,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,YVS,29915112,PubMed,10.1128/AEM.01032-18,Appl Environ Microbiol. 2018 Aug 1;84(16). pii: e01032-18,jw.mehat@surrey.ac.uk,"C. jejuni capC mutants displayed significantly reduced adherence to and invasion of non-polarized, partially differentiated Caco-2 and T84 intestinal epithelial cells.",J W Mehat 2018,2018,1 gene,"Mehat-2018-Characterisation of CapC, a novel a",BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11698,PHI:8239,UniProt,O53623,GenBank,CCP42801,,,H37Rv,Rv0078,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,TetR-like transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29921668,PubMed,10.1128/mBio.00989-18,MBio. 2018 Jun 19;9(3). pii: e00989-18,heran.darwin@med.nyu.edu,Constitutive expression of Rv0077c did not affect antibiotic susceptibility or virulence in mice.,M I Samanovic 2018,2018,1 gene,Samanovic-2018-Cytokinin Signaling in Mycobact,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11699,PHI:8239,UniProt,O53623,GenBank,CCP42801,,,H37Rv,Rv0078,,Rv0078 W100R,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,TetR-like transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29921668,PubMed,10.1128/mBio.00989-18,MBio. 2018 Jun 19;9(3). pii: e00989-18,heran.darwin@med.nyu.edu,Constitutive expression of Rv0077c did not affect antibiotic susceptibility or virulence in mice.,M I Samanovic 2018,2018,1 gene,Samanovic-2018-Cytokinin Signaling in Mycobact,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11700,PHI:8240,UniProt,A0A0F6B0Y6,GenBank,ACY88164,,,14028S,ssrB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11701,PHI:8241,UniProt,A0A0F6AWY4,GenBank,ACY86755,,,14028S,dksA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,RNA polymerase-binding transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11702,PHI:8240,UniProt,A0A0F6B0Y6,GenBank,ACY88164,,,14028S,ssrB,,,,,,PHI:8241,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11703,PHI:8241,UniProt,A0A0F6AWY4,GenBank,ACY86755,,,14028S,dksA,,,,,,PHI:8240,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,RNA polymerase-binding transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11704,PHI:8242,UniProt,A0A0F6B630,GenBank,ACY89977,,,14028S,relA,,,,,,PHI:8243,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,(p)ppGpp synthetase I/GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11705,PHI:8243,UniProt,A0A0F6B8P3,GenBank,ACY90891,,,14028S,spoT,,,,,,PHI:8242,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,bifunctional (P)ppGpp synthetase II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11706,PHI:8242,UniProt,A0A0F6B630,GenBank,ACY89977,,,14028S,relA,,,,,,PHI:8243; PHI:8240,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,(p)ppGpp synthetase I/GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11707,PHI:8243,UniProt,A0A0F6B8P3,GenBank,ACY90891,,,14028S,spoT,,,,,,PHI:8242; PHI:8240,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,bifunctional (P)ppGpp synthetase II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11708,PHI:8240,UniProt,A0A0F6B0Y6,GenBank,ACY88164,,,14028S,ssrB,,,,,,PHI:8242; PHI:8243,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11709,PHI:8244,UniProt,A0A0F6B0Y7,GenBank,ACY88165,,,14028S,ssrA,,ssrADsc,,,,PHI:8242; PHI:8243,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11710,PHI:8242,UniProt,A0A0F6B630,GenBank,ACY89977,,,14028S,relA,,,,,,PHI:8243; PHI:8244,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,(p)ppGpp synthetase I/GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11711,PHI:8243,UniProt,A0A0F6B8P3,GenBank,ACY90891,,,14028S,spoT,,,,,,PHI:8242; PHI:8244,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,bifunctional (P)ppGpp synthetase II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11712,PHI:8244,UniProt,A0A0F6B0Y7,GenBank,ACY88165,,,14028S,ssrA,,ssrADsc,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,oral mucosa,sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11713,PHI:8244,UniProt,A0A0F6B0Y7,GenBank,ACY88165,,,14028S,ssrA,,,,,,PHI:8240,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,oral mucosa,sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11714,PHI:8240,UniProt,A0A0F6B0Y6,GenBank,ACY88164,,,14028S,ssrB,,,,,,PHI:8244,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,oral mucosa,transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11715,PHI:8240,UniProt,A0A0F6B0Y6,GenBank,ACY88164,,,14028S,ssrB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,oral mucosa,transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence.,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11716,PHI:8244,UniProt,A0A0F6B0Y7,GenBank,ACY88165,,,14028S,ssrA,,ssrADsc,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,J-774 cell,sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence. macrophage-like cells,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11717,PHI:8244,UniProt,A0A0F6B0Y7,GenBank,ACY88165,,,14028S,ssrA,,,,,,PHI:8240,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,J-774 cell,sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence. macrophage-like cells,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11718,PHI:8240,UniProt,A0A0F6B0Y6,GenBank,ACY88164,,,14028S,ssrB,,,,,,PHI:8244,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,J-774 cell,transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence. macrophage-like cells,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11719,PHI:8240,UniProt,A0A0F6B0Y6,GenBank,ACY88164,,,14028S,ssrB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,J-774 cell,transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29930310,PubMed,10.1038/s41598-018-27780-9,Sci Rep. 2018 Jun 21;8(1):9465,andres.vazquez-torres@ucdenver.edu,Overexpression of SsrB diminished Salmonella virulence. macrophage-like cells,T Tapscott 2018,2018,5 genes,Tapscott-2018-Guanosine tetraphosphate relieve,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11720,PHI:8245,,no data found,,,,,,CtxAB5,,,,,,,666,Vibrio cholerae,,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,small intestine,Cholera toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29912959,PubMed,10.1371/journal.ppat.1007133,PLoS Pathog. 2018 Jun 18;14(6):e1007133,a1varki@ucsd.edu,"Host gene alteration data available for N-acetylneuraminic acid (Neu5Ac). Although the lack of Neu5Gc increased susceptibility to Ctx toxicity, the Cmah-/-background was not sufficient in itself to make mice susceptible to frank experimental diarrhea induced by oral infection with V. cholera.",F Alisson-Silva 2018,2018,2 genes,Alisson-Silva-2018-Human evolutionary loss of,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11721,PHI:8246,UniProt,C3LNA3,GenBank,ACP06029,,,M66-2,VcN,,,,,,,666,Vibrio cholerae,,serotype O1 biovar El Tor strain N16961,cholera,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,small intestine,neuraminidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,29912959,PubMed,10.1371/journal.ppat.1007133,PLoS Pathog. 2018 Jun 18;14(6):e1007133,a1varki@ucsd.edu,Host gene alteration data available for N-acetylneuraminic acid (Neu5Ac). Human epithelial cells artificially expressing Neu5Gc were less susceptible to Ctx binding and CtxA intoxication following VcN treatment.,F Alisson-Silva 2018,2018,2 genes,Alisson-Silva-2018-Human evolutionary loss of,BATCH_084B,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11722,PHI:8247,UniProt,Q8FBY0,GenBank,ART41963,,,81009,yicS,,,,,,,562,Escherichia coli,,APEC strain SCI-07,colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,lung; liver; heart,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30031479,PubMed,10.1016/j.micres.2018.05.009,Microbiol Res. 2018 Sep;214:28-36,wds@unicamp.br,"Adhesion to HeLa cell line was not impaired, intra-macrophage survival in HD11 cells also showed no differences, however, the ability of the mutant ΔyicS strain to invade and multiply in the human larynx cell line Hep-2 and avian fibroblast line CEC-32 was severely impaired compared to the wild type strain SCI-07.",R Verma 2018,2018,1 gene,Verma-2018-Role of hypothetical protein YicS i,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11723,PHI:8248,,no data found,,,,,,sssP1,,Δ50K-CZ130302,,,,,1307,Streptococcus suis,,CZ130302,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung; blood; kidney,putative secretory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,30030221,PubMed,10.1128/AEM.01385-18,Appl Environ Microbiol. 2018 Jul 20. pii: AEM.01385-18,yaohch@njau.edu.cn,50K genomic island (GI) facilitated the in vivo bacterial proliferation and contributed to the virulence of strain CZ130302. The sssP1 mutation attenuated bacterial adherence in HEp-2 and HBMEC cells when compared with the wild-type.,Y Zhang 2018,2018,1 gene,"Zhang-2018-Sssp1, a Streptococcus suis fimbria",BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11724,PHI:8248,,no data found,,,,,,sssP1,,Δ58K-CZ130302,,,,,1307,Streptococcus suis,,CZ130302,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung; blood; kidney,putative secretory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,30030221,PubMed,10.1128/AEM.01385-18,Appl Environ Microbiol. 2018 Jul 20. pii: AEM.01385-18,yaohch@njau.edu.cn,50K genomic island (GI) facilitated the in vivo bacterial proliferation and contributed to the virulence of strain CZ130302. The sssP1 mutation attenuated bacterial adherence in HEp-2 and HBMEC cells when compared with the wild-type.,Y Zhang 2018,2018,1 gene,"Zhang-2018-Sssp1, a Streptococcus suis fimbria",BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11725,PHI:8249,UniProt,A0A0H2Z7G2,GenBank,ABJ10113,,,UCBPP-PA14,PA14_51940 (PA0952),,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30042200,PubMed,10.1128/mBio.01310-18,MBio. 2018 Jul 24;9(4). pii: e01310-18,burrowl@mcmaster.ca,PilSR deletion mutants had defects in swimming motility that were independent of the loss of PilA.,S L N Kilmury 2018,2018,6 genes,Kilmury-2018-The Pseudomonas aeruginosa PilSR,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11726,PHI:8250,UniProt,A0A0H2ZFX1,GenBank,ABJ13300,,,UCBPP-PA14,PA14_11740 (PA4027),,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30042200,PubMed,10.1128/mBio.01310-18,MBio. 2018 Jul 24;9(4). pii: e01310-18,burrowl@mcmaster.ca,PilSR deletion mutants had defects in swimming motility that were independent of the loss of PilA.,S L N Kilmury 2018,2018,6 genes,Kilmury-2018-The Pseudomonas aeruginosa PilSR,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11727,PHI:8251,UniProt,A0A0H2ZHR7,GenBank,ABJ14064,,,UCBPP-PA14,PA14_61950 (PA4683),,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30042200,PubMed,10.1128/mBio.01310-18,MBio. 2018 Jul 24;9(4). pii: e01310-18,burrowl@mcmaster.ca,PilSR deletion mutants had defects in swimming motility that were independent of the loss of PilA.,S L N Kilmury 2018,2018,6 genes,Kilmury-2018-The Pseudomonas aeruginosa PilSR,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11728,PHI:8252,UniProt,A0A0H2Z8M3,GenBank,ABJ10692,,,UCBPP-PA14,"PA14_44890 (PA1512, hcpA)",,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,secreted protein (T6S),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30042200,PubMed,10.1128/mBio.01310-18,MBio. 2018 Jul 24;9(4). pii: e01310-18,burrowl@mcmaster.ca,PilSR deletion mutants had defects in swimming motility that were independent of the loss of PilA.,S L N Kilmury 2018,2018,6 genes,Kilmury-2018-The Pseudomonas aeruginosa PilSR,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11729,PHI:8253,UniProt,A0A0H2ZHV8,GenBank,ABJ14611,,,UCBPP-PA14,PA14_69040 (PA5228),,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30042200,PubMed,10.1128/mBio.01310-18,MBio. 2018 Jul 24;9(4). pii: e01310-18,burrowl@mcmaster.ca,PilSR deletion mutants had defects in swimming motility that were independent of the loss of PilA.,S L N Kilmury 2018,2018,6 genes,Kilmury-2018-The Pseudomonas aeruginosa PilSR,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11730,PHI:8254,UniProt,A0A0H2Z8M3,GenBank,ABJ14652,,,UCBPP-PA14,"PA14_69560 (PA5267, hcpB)",,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,secreted protein (T6S),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30042200,PubMed,10.1128/mBio.01310-18,MBio. 2018 Jul 24;9(4). pii: e01310-18,burrowl@mcmaster.ca,PilSR deletion mutants had defects in swimming motility that were independent of the loss of PilA.,S L N Kilmury 2018,2018,6 genes,Kilmury-2018-The Pseudomonas aeruginosa PilSR,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11731,PHI:8255,UniProt,Q8Y982,GenBank,CAC98729,,,EGD-e,MouR (Lmo0651),,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transcriptional activator of Agr system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30011022,PubMed,10.1093/nar/gky624,Nucleic Acids Res. 2018 Jul 12,srsousa@ibmc.up.pt,"Data indicated that MouR is necessary for Lm virulence in a mouse oral inoculation model, though not in an IV inoculation murine model.",J Pinheiro 2018,2018,1 gene,Pinheiro-2018-MouR controls the expression of,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11732,PHI:8256,UniProt,A0A0H2ZNN3,GenBank,ABJ54204,,,D39,SPD_1590,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,iron transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30079056,PubMed,10.3389/fmicb.2018.01624,Front Microbiol. 2018 Jul 20;9:1624,tsunxs@jnu.edu.cn,Spd1590 deletion significantly reduced both the adhesion and intracellular invasion of S. pneumoniae compared to WT. lung carcinoma cells,X Miao 2018,2018,1 gene,Miao-2018-A Novel Iron Transporter SPD_1590 in,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11733,PHI:8256,UniProt,A0A0H2ZNN3,GenBank,ABJ54204,,,D39,SPD_1590,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,iron transporter,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30079056,PubMed,10.3389/fmicb.2018.01624,Front Microbiol. 2018 Jul 20;9:1624,tsunxs@jnu.edu.cn,Spd1590 deletion significantly reduced both the adhesion and intracellular invasion of S. pneumoniae compared to WT. lung carcinoma cells,X Miao 2018,2018,1 gene,Miao-2018-A Novel Iron Transporter SPD_1590 in,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11734,PHI:8257,UniProt,A0A0H3JGP4,GenBank,AE005437_4,,,EDL933,z3276,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,fimbrial protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30072979,PubMed,10.3389/fmicb.2018.01628,Front Microbiol. 2018 Jul 19;9:1628,liuxuehan1996@hotmail.com,"The adhesion and invasion ability of Δz3276 to HEp-2 cells showed no significant change, but the invasion ability of 1z3276 to IPEC-J2 cells was attenuated.",B Zhang 2018,2018,1 gene,Zhang-2018-The Fimbrial Gene z3276 in Enterohe,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11735,PHI:8258,UniProt,J9VI98,GenBank,AFR93131,,,H99,vps45 (CNAG_03628),chromosome 2,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; liver; spleen; kidney; blood,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,rotenone; malonic acid; oligomycin; salicylhydroxamic acid (SHAM); antimycin A; potassium cyanide (KCN); hydrogen peroxide (H2O2); paraquat; plumbagin; diphenyleneiodonium chloride (dpi); menadione; aminodarone; cyclosporine A; tacrolimus (FK506); EGTA; miconazole; fluconazole,"rotenone: CHEBI:28201; malonic acid: CHEBI:30794; oligomycin: CHEBI:25675; salicylhydroxamic acid (SHAM): CHEBI:45615; antimycin A: CHEBI:22584; potassium cyanide (KCN): CHEBI:33191; hydrogen peroxide (H2O2): CHEBI:16240; paraquat: CHEBI:34905; plumbagin: CHEBI:8273; diphenyleneiodonium chloride (dpi): CHEBI:77967; menadione: CHEBI:28869; aminodarone: CHEBI:2663; cyclosporine A: CHEBI:4031; tacrolimus (FK506): CHEBI:61049; EGTA: CHEBI:30740; miconazole: CHEBI:6923; fluconazole: CHEBI:46081, CAS:86386-73-4",,,,,gene deletion: full; gene complementation,,,YVS,30071112,PubMed,10.1371/journal.ppat.1007220,PLoS Pathog. 2018 Aug 2;14(8):e1007220,Kronstad@msl.ubc.ca,Vps45 was required for survival in macrophages and virulence in mice.,M Caza 2018,2018,1 gene,Caza-2018-The Sec1_Munc18 (SM) protein Vps45 i,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11736,PHI:8259,UniProt,A0A0F6AZI6,GenBank,ACY87660,,,14028S,gtgA,,GtgA 20 -228 E183Q,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,type III secretion system effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30049795,PubMed,10.1074/jbc.RA118.004255,J Biol Chem. 2018 Jul 26. pii: jbc.RA118.004255,t.thurston@imperial.ac.uk,"Host gene alteration data available for NF-kB subunit p65. Mutation of the glutamate residue in the metal binding HEXXH motif of gtgA effector to alanine, abrogated NF-kB subunit cleavage, confirming that the catalytic activity of this effector was required for function.",E Jennings 2018,2018,1 gene,Jennings-2018-Structure-function analyses of t,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11737,PHI:8259,UniProt,A0A0F6AZI6,GenBank,ACY87660,,,14028S,gtgA,,GtgA 20 -228 E183Q,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HEK-293ET cell line,,,HEK-293ET cell,type III secretion system effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30049795,PubMed,10.1074/jbc.RA118.004255,J Biol Chem. 2018 Jul 26. pii: jbc.RA118.004255,t.thurston@imperial.ac.uk,"Host gene alteration data available for NF-kB subunit p65. Mutation of the glutamate residue in the metal binding HEXXH motif of gtgA effector to alanine, abrogated NF-kB subunit cleavage, confirming that the catalytic activity of this effector was required for function. embryonic kidney cells",E Jennings 2018,2018,1 gene,Jennings-2018-Structure-function analyses of t,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11738,PHI:8260,UniProt,A0A346B5J7,GenBank,AXL48515,,,CYR32,PsKPP4,,,,PsUBC2,GenBank: AXL48516,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,MAP kinase kinase kinase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,30047240,PubMed,10.1111/mpp.12731,Mol Plant Pathol. 2018 Jul 26,guojunwgq@nwsuaf.edu.cn,"PsKPP4, which acts by interacting with PsUBC2, participated in fungal development and contributes to the pathogenicity of Pst.",X Zhu 2018,2018,3 genes,"Zhu-2018-Silencing PsKPP4, a MAP kinase kinase",BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11739,PHI:8261,UniProt,A0A346B5J8,GenBank,AXL48516,,,CYR32,PsUBC2,,,,PsKPP4,GenBank: AXL48515,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,MAP kinase pathway interacting protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,30047240,PubMed,10.1111/mpp.12731,Mol Plant Pathol. 2018 Jul 26,guojunwgq@nwsuaf.edu.cn,"PsKPP4, which acts by interacting with PsUBC2, participated in fungal development and contributes to the pathogenicity of Pst.",X Zhu 2018,2018,3 genes,"Zhu-2018-Silencing PsKPP4, a MAP kinase kinase",BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11740,PHI:8262,UniProt,G4N7X0,GenBank,EHA50924,,,70-15,mst11,,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. NB6,,,leaf,STE/STE11 protein kinase,,,,reduced virulence,,yes,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30047240,PubMed,10.1111/mpp.12731,Mol Plant Pathol. 2018 Jul 26,guojunwgq@nwsuaf.edu.cn,PsKPP4 partially complemented the mst11 function in appressorium formation and plant infection.,X Zhu 2018,2018,3 genes,"Zhu-2018-Silencing PsKPP4, a MAP kinase kinase",BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11741,PHI:8260,UniProt,A0A346B5J7,GenBank,AXL48515,,,CYR32,PsKPP4,,,,,,PHI:8262,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. NB6,,,leaf,MAP kinase kinase kinase,,,,unaffected pathogenicity,,no,,,,,,,,no,,,,,,,other evidence: heterologous complementation,,,YVS,30047240,PubMed,10.1111/mpp.12731,Mol Plant Pathol. 2018 Jul 26,guojunwgq@nwsuaf.edu.cn,PsKPP4 partially complemented the mst11 function in appressorium formation and plant infection.,X Zhu 2018,2018,3 genes,"Zhu-2018-Silencing PsKPP4, a MAP kinase kinase",BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11742,PHI:8262,UniProt,G4N7X0,GenBank,EHA50924,,,70-15,mst11,chromosome 4,,,,,PHI:8260,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. NB6,,,leaf,STE/STE11 protein kinase,,,,unaffected pathogenicity,,no,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30047240,PubMed,10.1111/mpp.12731,Mol Plant Pathol. 2018 Jul 26,guojunwgq@nwsuaf.edu.cn,PsKPP4 partially complemented the mst11 function in appressorium formation and plant infection.,X Zhu 2018,2018,3 genes,"Zhu-2018-Silencing PsKPP4, a MAP kinase kinase",BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11743,PHI:8263,UniProt,I1S9X9,GenBank,XP_011327831,,,PH-1; NRRL 31084,Fgatg9 (FGSG_13660),chromosome 4,,,Fgrab7,UniProt: I1RAB7; GenBank: CEF72377,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,authophagy related protein,,,,reduced virulence,,,,,,wild type,wild type,reduced; aberrant,wild type,no,SDS; H2O2; DTT; NaCl; latrunculin A; nocodazole,SDS: CHEBI:8984; H2O2: CHEBI:16240; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; latrunculin A: CHEBI:69136; nocodazole: CHEBI:34892,,,,,gene deletion: full; gene complementation,,,YVS,30044782,PubMed,10.1371/journal.pgen.1007546,PLoS Genet. 2018 Jul 25;14(7):e1007546,wenhuiz@fafu.edu.cn,The deletion mutant (ΔFgatg9) shows severe defects in autophagy and lipid metabolism in response to carbon starvation.,H Zheng 2018,2018,2 genes,Zheng-2018-Small GTPase Rab7-mediated FgAtg9 t,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11744,PHI:8263,UniProt,I1S9X9,GenBank,XP_011327831,,,PH-1; NRRL 31084,Fgatg9 (FGSG_13660),chromosome 4,ΔFgatg9+MoATG9,,Fgrab7,UniProt: I1RAB7; GenBank: CEF72377,PHI:8264,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,authophagy related protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced; aberrant,wild type,no,SDS; H2O2; DTT; NaCl; latrunculin A; nocodazole,SDS: CHEBI:8984; H2O2: CHEBI:16240; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; latrunculin A: CHEBI:69136; nocodazole: CHEBI:34892,,,,,gene deletion: full; heterologous complementation,,,YVS,30044782,PubMed,10.1371/journal.pgen.1007546,PLoS Genet. 2018 Jul 25;14(7):e1007546,wenhuiz@fafu.edu.cn,The deletion mutant (ΔFgatg9) shows severe defects in autophagy and lipid metabolism in response to carbon starvation.,H Zheng 2018,2018,2 genes,Zheng-2018-Small GTPase Rab7-mediated FgAtg9 t,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11745,PHI:8264,UniProt,Q51WZ9,GenBank,EHA52375,,,70-15,atg9,chromosome 3,ΔFgatg9+MoATG9,,,,PHI:8263,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,authophagy related protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,reduced; aberrant,wild type,no,SDS; H2O2; DTT; NaCl; latrunculin A; nocodazole,SDS: CHEBI:8984; H2O2: CHEBI:16240; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; latrunculin A: CHEBI:69136; nocodazole: CHEBI:34892,,,,,other evidence: heterologous expression,,,YVS,30044782,PubMed,10.1371/journal.pgen.1007546,PLoS Genet. 2018 Jul 25;14(7):e1007546,wenhuiz@fafu.edu.cn,The deletion mutant (ΔFgatg9) shows severe defects in autophagy and lipid metabolism in response to carbon starvation.,H Zheng 2018,2018,2 genes,Zheng-2018-Small GTPase Rab7-mediated FgAtg9 t,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11746,PHI:8265,UniProt,A0A0H3I090,GenBank,AFI69755,,,1026b,lpxO (BP1026B_II1514),chromosome 2,,,,,,28450,Burkholderia pseudomallei,884204,1026b,melioidosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,hypothetical protein with probable aspartyl/asparaginyl beta-hydroxylase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30037795,PubMed,10.1128/IAI.00360-18,Infect Immun. 2018 Jul 23. pii: IAI.00360-18,mhnorris@ufl.edu,The lpxO-mediated hydroxylation of Bp lipid A was important for replication in the established RAW264.7 macrophage model and that pagL played a less significant role,M H Norris 2018,2018,2 genes,Norris-2018-Lipid A remodeling is a patho-adap,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11747,PHI:8266,UniProt,A0A0H3HNI7,GenBank,AFI67576,,,1026b,pagL (BP1026B_I2991),chromosome 1,,,,,,28450,Burkholderia pseudomallei,884204,1026b,melioidosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,lipid A 3-O-deacylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30037795,PubMed,10.1128/IAI.00360-18,Infect Immun. 2018 Jul 23. pii: IAI.00360-18,mhnorris@ufl.edu,The lpxO-mediated hydroxylation of Bp lipid A was important for replication in the established RAW264.7 macrophage model and that pagL played a less significant role,M H Norris 2018,2018,2 genes,Norris-2018-Lipid A remodeling is a patho-adap,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11748,PHI:8267,,no data found,GenBank,CAR35580,,,P125109,alr (SEN4016),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,mesenteric lymph node; spleen; liver; cecum,alanine racemase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties.,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11749,PHI:8268,,no data found,GenBank,CAR32815,,,P125109,dadX (SEN1235),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,mesenteric lymph node; spleen; liver; cecum,alanine racemase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties.,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11750,PHI:8269,,no data found,GenBank,CAR35471,,,P125109,SEN3897,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,mesenteric lymph node; spleen; liver; cecum,alanine racemase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties.,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11751,PHI:8267,,no data found,GenBank,CAR35580,,,P125109,alr (SEN4016),,,,,,PHI:8268,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,mesenteric lymph node; spleen; liver; cecum,alanine racemase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties.,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11752,PHI:8268,,no data found,GenBank,CAR32815,,,P125109,dadX (SEN1235),,,,,,PHI:8267,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,mesenteric lymph node; spleen; liver; cecum,alanine racemase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties.,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11753,PHI:8267,,no data found,GenBank,CAR35580,,,P125109,alr (SEN4016),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,HCT-116 cell,alanine racemase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties. colon carcinoma cells,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11754,PHI:8268,,no data found,GenBank,CAR32815,,,P125109,dadX (SEN1235),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,HCT-116 cell,alanine racemase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties. colon carcinoma cells,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11755,PHI:8269,,no data found,GenBank,CAR35471,,,P125109,SEN3897,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,HCT-116 cell,alanine racemase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties. colon carcinoma cells,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11756,PHI:8267,,no data found,GenBank,CAR35580,,,P125109,alr (SEN4016),,,,,,PHI:8268,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,HCT-116 cell,alanine racemase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties. colon carcinoma cells,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11757,PHI:8268,,no data found,GenBank,CAR32815,,,P125109,dadX (SEN1235),,,,,,PHI:8267,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,HCT-116 cell,alanine racemase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties. colon carcinoma cells,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11758,PHI:8267,,no data found,GenBank,CAR35580,,,P125109,alr (SEN4016),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,alanine racemase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties.,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11759,PHI:8268,,no data found,GenBank,CAR32815,,,P125109,dadX (SEN1235),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,alanine racemase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties.,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11760,PHI:8269,,no data found,GenBank,CAR35471,,,P125109,SEN3897,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,alanine racemase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties.,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11761,PHI:8267,,no data found,GenBank,CAR35580,,,P125109,alr (SEN4016),,,,,,PHI:8268,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,alanine racemase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties.,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11762,PHI:8268,,no data found,GenBank,CAR32815,,,P125109,dadX (SEN1235),,,,,,PHI:8267,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,alanine racemase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30008809,PubMed,10.1186/s13099-018-0257-6,Gut Pathog. 2018 Jul 10;10:30,msuar@kiitbiotech.ac.in,SEN3897 by itself wasn't able to rescue D-alanine auxotrophy in S. Enteritidis which further contributed to its virulence properties.,S Ray 2018,2018,3 genes,Ray-2018-Identification of a new alanine racem,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11763,PHI:8270,UniProt,Q5ANG4,GenBank,AOW28494,,,SC5314,zcf32,chromosome 3,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,spleen; kidney; liver,Zn(II)2Cys6 transcription factor,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30052909,PubMed,10.1093/femsyr/foy078,FEMS Yeast Res. 2018 Jul 24,vraj@iisc.ac.in,Null mutants of each of Zcf32 or Upc2 form better biofilms than the wild-type suggesting that both of them negatively regulate the biofilm development.,P Kakade 2018,2018,2 genes,Kakade-2018-Two negative regulators of biofilm,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11764,PHI:8271,UniProt,Q59QC7,GenBank,AOW26484,,,SC5314,upc2,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,spleen; kidney; liver,Zn(II)2Cys6 transcription factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30052909,PubMed,10.1093/femsyr/foy078,FEMS Yeast Res. 2018 Jul 24,vraj@iisc.ac.in,Null mutants of each of Zcf32 or Upc2 form better biofilms than the wild-type suggesting that both of them negatively regulate the biofilm development.,P Kakade 2018,2018,2 genes,Kakade-2018-Two negative regulators of biofilm,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11765,PHI:8272,UniProt,P0AE82,GenBank,AAC76893,,,K-12,cpxA,,,,,,,562,Escherichia coli,,serotype O2:K1:H7 strain M78,avian colibacillosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,membrane sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30062827,PubMed,10.1111/1462-2920.14368,Environ Microbiol. 2018 Jul 30,miguel_angel_81@live.com,"Adherence, invasiveness, motility, production of type 1 fimbriae, and biofilm were negatively affected in the ΔcpxA mutant",L B Matter 2018,2018,2 genes,Matter-2018-The CpxRA stress response system r,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11766,PHI:8273,UniProt,P0AE88,GenBank,AAC76894,,,K-12,cpxR,,,,,,,562,Escherichia coli,,serotype O2:K1:H7 strain M78,avian colibacillosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,cytoplasmic transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30062827,PubMed,10.1111/1462-2920.14368,Environ Microbiol. 2018 Jul 30,miguel_angel_81@live.com,"Adherence, invasiveness, motility, production of type 1 fimbriae, and biofilm were negatively affected in the ΔcpxA mutant",L B Matter 2018,2018,2 genes,Matter-2018-The CpxRA stress response system r,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11767,PHI:8272,UniProt,P0AE82,GenBank,AAC76893,,,K-12,cpxA,,,,,,PHI:8273,562,Escherichia coli,,serotype O2:K1:H7 strain M78,avian colibacillosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,membrane sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30062827,PubMed,10.1111/1462-2920.14368,Environ Microbiol. 2018 Jul 30,miguel_angel_81@live.com,"Adherence, invasiveness, motility, production of type 1 fimbriae, and biofilm were negatively affected in the ΔcpxA mutant",L B Matter 2018,2018,2 genes,Matter-2018-The CpxRA stress response system r,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11768,PHI:8273,UniProt,P0AE88,GenBank,AAC76894,,,K-12,cpxR,,,,,,PHI:8272,562,Escherichia coli,,serotype O2:K1:H7 strain M78,avian colibacillosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,cytoplasmic transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30062827,PubMed,10.1111/1462-2920.14368,Environ Microbiol. 2018 Jul 30,miguel_angel_81@live.com,"Adherence, invasiveness, motility, production of type 1 fimbriae, and biofilm were negatively affected in the ΔcpxA mutant",L B Matter 2018,2018,2 genes,Matter-2018-The CpxRA stress response system r,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11769,PHI:8274,UniProt,Q4L0V2,GenBank,AAV54519,,,BO5-10,pacC,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Saxa,,,leaf,zinc finger transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30066486,PubMed,10.1111/1758-2229.12663,Environ Microbiol Rep. 2018 Aug 1,nathalie.poussereau@univ-lyon1.fr,"The capacity of the mutant to acidify its environment and, more particularly, to produce oxalic acid was affected, as was production of reactive oxygen species.",C Rascle 2018,2018,1 gene,Rascle-2018-The pH regulator PacC_ A host-depe,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11770,PHI:8274,UniProt,Q4L0V2,GenBank,AAV54519,,,BO5-10,pacC,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4232,Helianthus annuus (related: common sunflower),,,,cotyledon,zinc finger transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30066486,PubMed,10.1111/1758-2229.12663,Environ Microbiol Rep. 2018 Aug 1,nathalie.poussereau@univ-lyon1.fr,"The capacity of the mutant to acidify its environment and, more particularly, to produce oxalic acid was affected, as was production of reactive oxygen species.",C Rascle 2018,2018,1 gene,Rascle-2018-The pH regulator PacC_ A host-depe,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11771,PHI:8274,UniProt,Q4L0V2,GenBank,AAV54519,,,BO5-10,pacC,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,cotyledon,zinc finger transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30066486,PubMed,10.1111/1758-2229.12663,Environ Microbiol Rep. 2018 Aug 1,nathalie.poussereau@univ-lyon1.fr,"The capacity of the mutant to acidify its environment and, more particularly, to produce oxalic acid was affected, as was production of reactive oxygen species.",C Rascle 2018,2018,1 gene,Rascle-2018-The pH regulator PacC_ A host-depe,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11772,PHI:8274,UniProt,Q4L0V2,GenBank,AAV54519,,,BO5-10,pacC,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3663,Cucurbita pepo (no common name found),var. melopepo (zucchini),,,fruit,zinc finger transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30066486,PubMed,10.1111/1758-2229.12663,Environ Microbiol Rep. 2018 Aug 1,nathalie.poussereau@univ-lyon1.fr,"The capacity of the mutant to acidify its environment and, more particularly, to produce oxalic acid was affected, as was production of reactive oxygen species.",C Rascle 2018,2018,1 gene,Rascle-2018-The pH regulator PacC_ A host-depe,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11773,PHI:8274,UniProt,Q4L0V2,GenBank,AAV54519,,,BO5-10,pacC,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,zinc finger transcription factor,,,,unaffected pathogenicity,,,,,,reduced,,reduced,reduced,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30066486,PubMed,10.1111/1758-2229.12663,Environ Microbiol Rep. 2018 Aug 1,nathalie.poussereau@univ-lyon1.fr,"The capacity of the mutant to acidify its environment and, more particularly, to produce oxalic acid was affected, as was production of reactive oxygen species.",C Rascle 2018,2018,1 gene,Rascle-2018-The pH regulator PacC_ A host-depe,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11774,PHI:8274,UniProt,Q4L0V2,GenBank,AAV54519,,,BO5-10,pacC,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,zinc finger transcription factor,,,,unaffected pathogenicity,,,,,,reduced,,reduced,reduced,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30066486,PubMed,10.1111/1758-2229.12663,Environ Microbiol Rep. 2018 Aug 1,nathalie.poussereau@univ-lyon1.fr,"The capacity of the mutant to acidify its environment and, more particularly, to produce oxalic acid was affected, as was production of reactive oxygen species.",C Rascle 2018,2018,1 gene,Rascle-2018-The pH regulator PacC_ A host-depe,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11775,PHI:8274,UniProt,Q4L0V2,GenBank,AAV54519,,,BO5-10,pacC,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,zinc finger transcription factor,,,,unaffected pathogenicity,,,,,,reduced,,reduced,reduced,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30066486,PubMed,10.1111/1758-2229.12663,Environ Microbiol Rep. 2018 Aug 1,nathalie.poussereau@univ-lyon1.fr,"The capacity of the mutant to acidify its environment and, more particularly, to produce oxalic acid was affected, as was production of reactive oxygen species.",C Rascle 2018,2018,1 gene,Rascle-2018-The pH regulator PacC_ A host-depe,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11776,PHI:8275,UniProt,Q9I4B2,GenBank,AE004552_5,,,PAO1,PA1226,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29995308,PubMed,10.1111/mmi.14063,Mol Microbiol. 2018 Jul 11,tongh@hawaii.edu,"Mutation in the gene PA1226 abolished the ability of P. aeruginosa to produce biofilms in vitro, without any effect on the planktonic growth.",Y Heacock-Kang 2018,2018,1 gene,Heacock-Kang-2018-Novel dual regulators of Pse,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11777,PHI:8275,UniProt,Q9I4B2,GenBank,AE004552_5,,,PAO1,PA1226,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29995308,PubMed,10.1111/mmi.14063,Mol Microbiol. 2018 Jul 11,tongh@hawaii.edu,"Mutation in the gene PA1226 abolished the ability of P. aeruginosa to produce biofilms in vitro, without any effect on the planktonic growth.",Y Heacock-Kang 2018,2018,1 gene,Heacock-Kang-2018-Novel dual regulators of Pse,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11778,PHI:8276,UniProt,Q3BY51,GenBank,CAJ22212,,,85-10,XopB,,XopBΔ2-99,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30073738,PubMed,10.1111/mpp.12725,Mol Plant Pathol. 2018 Aug 2,ulla.bonas@genetik.uni-halle.de,"The XopB derivative lacking the N-terminal 99 aa (XopBΔ2-99) induced cell death in N. benthamiana, albeit weaker than the WT protein.",H Prochaska 2018,2018,3 genes,Prochaska-2018-A conserved motif promotes HpaB,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11779,PHI:8276,UniProt,Q3BY51,GenBank,CAJ22212,,,85-10,XopB,,XopB R/A,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30073738,PubMed,10.1111/mpp.12725,Mol Plant Pathol. 2018 Aug 2,ulla.bonas@genetik.uni-halle.de,"The XopB derivative lacking the N-terminal 99 aa (XopBΔ2-99) induced cell death in N. benthamiana, albeit weaker than the WT protein.",H Prochaska 2018,2018,3 genes,Prochaska-2018-A conserved motif promotes HpaB,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11780,PHI:8276,UniProt,Q3BY51,GenBank,CAJ22212,,,85-10,XopB,,XopBΔ2-99,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30073738,PubMed,10.1111/mpp.12725,Mol Plant Pathol. 2018 Aug 2,ulla.bonas@genetik.uni-halle.de,"The XopB derivative lacking the N-terminal 99 aa (XopBΔ2-99) induced cell death in N. benthamiana, albeit weaker than the WT protein.",H Prochaska 2018,2018,3 genes,Prochaska-2018-A conserved motif promotes HpaB,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11781,PHI:8276,UniProt,Q3BY51,GenBank,CAJ22212,,,85-10,XopB,,XopB R/A,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30073738,PubMed,10.1111/mpp.12725,Mol Plant Pathol. 2018 Aug 2,ulla.bonas@genetik.uni-halle.de,"The XopB derivative lacking the N-terminal 99 aa (XopBΔ2-99) induced cell death in N. benthamiana, albeit weaker than the WT protein.",H Prochaska 2018,2018,3 genes,Prochaska-2018-A conserved motif promotes HpaB,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11782,PHI:8277,UniProt,Q3C000,GenBank,CAJ19916,,,85-10,AvrBs1,,AvrBs1 1-111;P48-R51A::AvrBs3Δ2,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30073738,PubMed,10.1111/mpp.12725,Mol Plant Pathol. 2018 Aug 2,ulla.bonas@genetik.uni-halle.de,"Strains expressing the respective TrM mutants (AvrBs11-111;P48-R51A::AvrBs3Δ2, AvrBsTC222A;P57K60A::AvrBs3Δ2) caused delayed cell death reactions.",H Prochaska 2018,2018,3 genes,Prochaska-2018-A conserved motif promotes HpaB,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11783,PHI:8278,UniProt,G0T341,,,,,,AvrBsT,,AvrBsT C222A;P57K60A::AvrBs3Δ2,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30073738,PubMed,10.1111/mpp.12725,Mol Plant Pathol. 2018 Aug 2,ulla.bonas@genetik.uni-halle.de,"Strains expressing the respective TrM mutants (AvrBs11-111;P48-R51A::AvrBs3Δ2, AvrBsTC222A;P57K60A::AvrBs3Δ2) caused delayed cell death reactions.",H Prochaska 2018,2018,3 genes,Prochaska-2018-A conserved motif promotes HpaB,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11784,PHI:8279,,no data found,,,,,,mpe,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,mobile plasmid encoded element,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,K2CrO4; HgCl2,potassium chromate (K2CrO4): CHEBI:75249; mercury dichloride (HgCl2): CHEBI:31823,,,,,other evidence: recombinant plasmid,,,YVS,30063910,PubMed,10.1016/j.plasmid.2018.07.003,Plasmid. 2018 Jul 29;98:15-21,marthaisela_ramirez@hotmail.com,Transference of Mpe increased the virulence of P. aeruginosa PAO1 against the nematode Caenorhabditis elegans.,K C Hernandez-Ramirez 2018,2018,1 gene,Hernandez-Ramir-2018-A plasmid-encoded mobile,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11785,PHI:8280,UniProt,C5W022,GenBank,CAR45112,,,P1/7,ide,,C195S,,,,,1307,Streptococcus suis,,serotype 2 strain 10,meningitis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,"cysteine protease, IgM degrading enzyme",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30001174,PubMed,10.1080/21505594.2018.1496778,Virulence. 2018;9(1):1314-1337,christoph.baums@vetmed.uni-leipzig.de,IgM cleavage of S. suis serotype 2 was not crucial for causing meningitis in growing piglets.,V Rungelrath 2018,2018,1 gene,Rungelrath-2018-IgM cleavage by Streptococcus,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11786,PHI:8280,UniProt,C5W022,GenBank,CAR45112,,,P1/7,ide,,C195S,,,,,1307,Streptococcus suis,,serotype 2 strain 10,meningitis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,brain; cerebrospinal fluid; spleen; liver; lung; endocardium; peritoneum,"cysteine protease, IgM degrading enzyme",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30001174,PubMed,10.1080/21505594.2018.1496778,Virulence. 2018;9(1):1314-1337,christoph.baums@vetmed.uni-leipzig.de,IgM cleavage of S. suis serotype 2 was not crucial for causing meningitis in growing piglets.,V Rungelrath 2018,2018,1 gene,Rungelrath-2018-IgM cleavage by Streptococcus,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11787,PHI:8281,UniProt,Q8VQK4,GenBank,AAX76407,,,9-941,BruAb2_1031,chromosome II,,,,,,235,Brucella abortus,,1119-3,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,ATP-binding cassette transporter permease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30064361,PubMed,10.1186/s12866-018-1223-7,BMC Microbiol. 2018 Jul 31;18(1):82,yoohs@snu.ac.kr,Wild-type had a lower level of intracellular survival as compared to the mutant strains.,M Jung 2018,2018,3 genes,Jung-2018-Global gene-expression profiles of i,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11788,PHI:8282,UniProt,Q579X1,GenBank,AAX75563,,,9-941,BruAb2_0113,chromosome II,,,,,,235,Brucella abortus,,1119-3,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,ABC transporter substrate-binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30064361,PubMed,10.1186/s12866-018-1223-7,BMC Microbiol. 2018 Jul 31;18(1):82,yoohs@snu.ac.kr,Wild-type had a lower level of intracellular survival as compared to the mutant strains.,M Jung 2018,2018,3 genes,Jung-2018-Global gene-expression profiles of i,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11789,PHI:8283,UniProt,Q578J2,GenBank,AAX75942,,,9-941,ahpD,chromosome II,,,,,,235,Brucella abortus,,1119-3,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,alkyl hydroperoxide reductase D,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30064361,PubMed,10.1186/s12866-018-1223-7,BMC Microbiol. 2018 Jul 31;18(1):82,yoohs@snu.ac.kr,Wild-type had a lower level of intracellular survival as compared to the mutant strains.,M Jung 2018,2018,3 genes,Jung-2018-Global gene-expression profiles of i,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11790,PHI:8284,,no data found,,,,,,CreA,,,,,,,27334,Penicillium expansum,,TJT1.1,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,global carbon catabolite regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30047230,PubMed,10.1111/mpp.12734,Mol Plant Pathol. 2018 Jul 26,npkeller@wisc.edu,Loss-of-function creA strains were nearly avirulent and did not produce patulin in apples.,J Tannous 2018,2018,1 gene,Tannous-2018-Fungal attack and host defense pa,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11791,PHI:8285,UniProt,H6BVA1,GenBank,EHY55015,,,NIH/UT8656,PKS1 (HMPREF1120_03173),,,,,,,5970,Exophiala dermatitidis,,CBS 525.76,cutaneous infection,primates,9606,Homo sapiens (related: human),,,,skin,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30018609,PubMed,10.3389/fmicb.2018.01457,Front Microbiol. 2018 Jul 3;9:1457,katja.sterflinger@boku.ac.at,The mutant had only partially covered the skin and showed no invasiveness.,C Poyntner 2018,2018,1 gene,Poyntner-2018-Transcriptome Study of an Exophi,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11792,PHI:8286,UniProt,A0A1D8PF54,GenBank,AOW26772,,,SC5314,PHO84,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis; oropharyngeal candidiasis,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,phosphate transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30018609,PubMed,10.1371/journal.ppat.1007076,PLoS Pathog. 2018 Jul 30;14(7):e1007076,julia.koehler@childrens.harvard.edu,"Pho84-/- mutants hyperactivated oxidativestress signalling and they accumulated intracellular ROS in the absence of extrinsic oxidative stress, in high as well as low ambient phosphate conditions.",N N Liu 2018,2018,1 gene,Liu-2018-Intersection of phosphate transport,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11793,PHI:8286,UniProt,A0A1D8PF54,GenBank,AOW26772,,,SC5314,PHO84,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis; oropharyngeal candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue; kidney,phosphate transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30018609,PubMed,10.1371/journal.ppat.1007076,PLoS Pathog. 2018 Jul 30;14(7):e1007076,julia.koehler@childrens.harvard.edu,"Pho84-/- mutants hyperactivated oxidativestress signalling and they accumulated intracellular ROS in the absence of extrinsic oxidative stress, in high as well as low ambient phosphate conditions.",N N Liu 2018,2018,1 gene,Liu-2018-Intersection of phosphate transport,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11794,PHI:8287,UniProt,A0A0H3W4K4,GenBank,AKJ32477,,,SLW01,Lip40,,,,,,,715,Actinobacillus pleuropneumoniae,,SLW01,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,outer membrane lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30018613,PubMed,10.3389/fmicb.2018.01472,Front Microbiol. 2018 Jul 3;9:1472,qichao@mail.ccnu.edu.cn,Δlip40 exhibited reduced adherence to the St. Jude porcine lung epithelial line.,J Liu 2018,2018,1 gene,Liu-2018-Outer Membrane Lipoprotein Lip40 Modu,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11795,PHI:8287,UniProt,A0A0H3W4K4,GenBank,AKJ32477,,,SLW01,Lip40,,,,,,,715,Actinobacillus pleuropneumoniae,,SLW01,pleuropneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,lung,outer membrane lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30018613,PubMed,10.3389/fmicb.2018.01472,Front Microbiol. 2018 Jul 3;9:1472,qichao@mail.ccnu.edu.cn,Δlip40 exhibited reduced adherence to the St. Jude porcine lung epithelial line.,J Liu 2018,2018,1 gene,Liu-2018-Outer Membrane Lipoprotein Lip40 Modu,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11796,PHI:8288,UniProt,A0A0F6AZ30,GenBank,ACY87504,,,14028S,LoiA (STM14_1008),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30077369,PubMed,10.1016/j.bbrc.2018.07.151,Biochem Biophys Res Commun. 2018 Aug 1. pii: S0006-291X(18)31655-3,liubin1981@nankai.edu.cn,LoiA did not influence the replication ability of S. Typhimurium in macrophages.,H Li 2018,2018,1 gene,Li-2018-Global regulatory function of the low,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11797,PHI:8289,UniProt,A0A069PXM1,GenBank,CEI15988,,,MH19,ctpA,,,,lbcA,UniProt: P42810; GenBank: AE004880_10,,287,Pseudomonas aeruginosa,1009714,PAK,nosocomial infection,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO-K1 cell line,,,CHO-K1 cell,carboxy-terminal processing protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30018106,PubMed,10.1128/mBio.00972-18,MBio. 2018 Jul 17;9(4). pii: e00972-18,andrew.darwin@med.nyu.edu,"ΔMepM did not affect cytotoxicity, but ΔctpA reduced it, and this reduction was suppressed in the ΔctpA ΔmepM double mutant. Chinese hamster ovary cells",D Srivastava 2018,2018,2 genes,Srivastava-2018-A Proteolytic Complex Targets,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11798,PHI:8290,UniProt,Q9I5Q4,GenBank,AE004501_8,,,PAO1,mepM (PA0667),,,,,,,287,Pseudomonas aeruginosa,1009714,PAK,nosocomial infection,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO-K1 cell line,,,CHO-K1 cell,DD-endopeptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30018106,PubMed,10.1128/mBio.00972-18,MBio. 2018 Jul 17;9(4). pii: e00972-18,andrew.darwin@med.nyu.edu,"ΔMepM did not affect cytotoxicity, but ΔctpA reduced it, and this reduction was suppressed in the ΔctpA ΔmepM double mutant. Chinese hamster ovary cells",D Srivastava 2018,2018,2 genes,Srivastava-2018-A Proteolytic Complex Targets,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11799,PHI:8289,UniProt,A0A069PXM1,GenBank,CEI15988,,,MH19,ctpA,,,,lbcA,UniProt: P42810; GenBank: AE004880_10,PHI:8290,287,Pseudomonas aeruginosa,1009714,PAK,nosocomial infection,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO-K1 cell line,,,CHO-K1 cell,carboxy-terminal processing protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30018106,PubMed,10.1128/mBio.00972-18,MBio. 2018 Jul 17;9(4). pii: e00972-18,andrew.darwin@med.nyu.edu,"ΔMepM did not affect cytotoxicity, but ΔctpA reduced it, and this reduction was suppressed in the ΔctpA ΔmepM double mutant. Chinese hamster ovary cells",D Srivastava 2018,2018,2 genes,Srivastava-2018-A Proteolytic Complex Targets,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11800,PHI:8290,UniProt,Q9I5Q4,GenBank,AE004501_8,,,PAO1,mepM (PA0667),,,,,,PHI:8289,287,Pseudomonas aeruginosa,1009714,PAK,nosocomial infection,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO-K1 cell line,,,CHO-K1 cell,DD-endopeptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30018106,PubMed,10.1128/mBio.00972-18,MBio. 2018 Jul 17;9(4). pii: e00972-18,andrew.darwin@med.nyu.edu,"ΔMepM did not affect cytotoxicity, but ΔctpA reduced it, and this reduction was suppressed in the ΔctpA ΔmepM double mutant. Chinese hamster ovary cells",D Srivastava 2018,2018,2 genes,Srivastava-2018-A Proteolytic Complex Targets,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11801,PHI:8291,UniProt,B8NQE4,GenBank,EED47982,,,NRRL3357,rum1 (AFLA_006240),,,,,,,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG::AfpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,PHD transcription factor,,,aflatoxin biosynthesis,reduced virulence,,,,,,increased; aberrant,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30036940,PubMed,10.3390/toxins10070301,Toxins (Basel). 2018 Jul 20;10(7). pii: E301,ZH_Zhuang@fafu.edu.cn,"Rum1 negatively regulated conidiation, positively regulated sclerotia formation, triggered alfatoxin biosynthesis and enhanced the activity of amylase.",Y Hu 2018,2018,1 gene,Hu-2018-The PHD Transcription Factor Rum1 Regu,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11802,PHI:8291,UniProt,B8NQE4,GenBank,EED47982,,,NRRL3357,rum1 (AFLA_006240),,,,,,,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG::AfpyrG),ear rot (corn); yellow mold (peanut),monocots,3818,Arachis hypogaea (related: peanut),,,,kernel,PHD transcription factor,,,aflatoxin biosynthesis,reduced virulence,,,,,,increased; aberrant,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30036940,PubMed,10.3390/toxins10070301,Toxins (Basel). 2018 Jul 20;10(7). pii: E301,ZH_Zhuang@fafu.edu.cn,"Rum1 negatively regulated conidiation, positively regulated sclerotia formation, triggered alfatoxin biosynthesis and enhanced the activity of amylase.",Y Hu 2018,2018,1 gene,Hu-2018-The PHD Transcription Factor Rum1 Regu,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11803,PHI:8292,UniProt,Q87GF7,GenBank,BAC62702,,,O3:K6,vpa1359,chromosome 2,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,KCl,KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,30042203,PubMed,10.1128/mBio.01366-18,MBio. 2018 Jul 24;9(4). pii: e01366-18,kodama@biken.osaka-u.ac.jp,Vpa1360 and vpa1359 were required for T3SS2-dependent enterotoxicity in the rabbit ileal loop model. colon carcinoma cell line,S Tandhavanant 2018,2018,2 genes,Tandhavanant-2018-Vibrio parahaemolyticus Sens,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11804,PHI:8293,UniProt,Q87GF6,GenBank,BAC62703,,,O3:K6,vpa1360,chromosome 2,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,KCl,KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,30042203,PubMed,10.1128/mBio.01366-18,MBio. 2018 Jul 24;9(4). pii: e01366-18,kodama@biken.osaka-u.ac.jp,Vpa1360 and vpa1359 were required for T3SS2-dependent enterotoxicity in the rabbit ileal loop model. colon carcinoma cell line,S Tandhavanant 2018,2018,2 genes,Tandhavanant-2018-Vibrio parahaemolyticus Sens,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11805,PHI:8292,UniProt,Q87GF7,GenBank,BAC62702,,,O3:K6,vpa1359,chromosome 2,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,ileum,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,KCl,KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,30042203,PubMed,10.1128/mBio.01366-18,MBio. 2018 Jul 24;9(4). pii: e01366-18,kodama@biken.osaka-u.ac.jp,Vpa1360 and vpa1359 were required for T3SS2-dependent cytotoxicity against Caco-2 cells after 6h of infection. ileal loop,S Tandhavanant 2018,2018,2 genes,Tandhavanant-2018-Vibrio parahaemolyticus Sens,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11806,PHI:8293,UniProt,Q87GF6,GenBank,BAC62703,,,O3:K6,vpa1360,chromosome 2,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,ileum,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,KCl,KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,30042203,PubMed,10.1128/mBio.01366-18,MBio. 2018 Jul 24;9(4). pii: e01366-18,kodama@biken.osaka-u.ac.jp,Vpa1360 and vpa1359 were required for T3SS2-dependent cytotoxicity against Caco-2 cells after 6h of infection. ileal loop,S Tandhavanant 2018,2018,2 genes,Tandhavanant-2018-Vibrio parahaemolyticus Sens,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11807,PHI:8294,,no data found,GenBank,ABS90210,,,ATCC 17978,Hfq (A1S_3785),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen,hypothetical protein,,,,reduced virulence,,,,,,,,reduced,,no,"NaCl; 2,2-dipyridyl; nalidixic acid; gentamycin; meropenem","NaCl: CHEBI:26710; 2,2-dipyridyl: CHEBI:30351; nalidixic acid: CHEBI:100147; gentamycin: CHEBI:17833; meropenem: CHEBI:43968",,,,,gene deletion: full; gene complementation,,,YVS,30002121,PubMed,10.1074/jbc.RA118.002921,J Biol Chem. 2018 Jul 12. pii: jbc.RA118.002921,ranjanapathania@gmail.com,The bacterial load in mice in case of cells expressing Hfq lacking the CTR was higher than the deletion mutant but significantly less than the cells expressing full length Hfq.,A Sharma 2018,2018,1 gene,Sharma-2018-The unusual glycine rich C-terminu,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11808,PHI:8294,,no data found,GenBank,ABS90210,,,ATCC 17978,Hfq (A1S_3785),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),HEK-293 cell line,,,epithelial cell,hypothetical protein,,,,reduced virulence,,,,,,,,reduced,,no,"NaCl; 2,2-dipyridyl; nalidixic acid; gentamycin; meropenem","NaCl: CHEBI:26710; 2,2-dipyridyl: CHEBI:30351; nalidixic acid: CHEBI:100147; gentamycin: CHEBI:17833; meropenem: CHEBI:43968",,,,,gene deletion: full; gene complementation,,,YVS,30002121,PubMed,10.1074/jbc.RA118.002921,J Biol Chem. 2018 Jul 12. pii: jbc.RA118.002921,ranjanapathania@gmail.com,Adherence of A. baumannii cells expressing Hfq lacking the C-terminus was only partially restored in HEK 293 cells.,A Sharma 2018,2018,1 gene,Sharma-2018-The unusual glycine rich C-terminu,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11809,PHI:8295,,no data found,,,,,,Sshk,,,,,,,5180,Sclerotinia sclerotiorum,,HLJ4,white mold,eudicots,3659,Cucumis sativus (related: cucumber),cv. Xinjinyou 1,,,leaf,group III histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,sodium dodecyl sulfate; Congo red; NaCl; glucose; sucrose; glycerol; hydrogen peroxide; dimethachlone,sodium dodecyl sulfate: CHEBI:8984; Congo red: CHEBI:34653; NaCl: CHEBI:26710; glucose: CHEBI:17234; sucrose: CHEBI:17992; glycerol: CHEBI:17754; hydrogen peroxide: CHEBI:16240; dimethachlone CAS no.: CAS:24096-53-5,,,,,altered gene expression / gene regulation: silencing,,,YVS,30070619,PubMed,10.1094/PHYTO-05-18-0156-R,Phytopathology. 2018 Aug 2,jianhl@mail.hzau.edu.cn,Overexpression of Sshk has a negative effect on the virulence of S. sclerotiorum and resulted in resistance to dimethachlone and increased sensitivity to various stresses and to the cell wall perturbing agents.,J Li 2018,2018,1 gene,Li-2018-Expression of the histidine kinase gen,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11810,PHI:8295,,no data found,,,,,,Sshk,,,,,,,5180,Sclerotinia sclerotiorum,,HLJ4,white mold,eudicots,3708,Brassica napus (related: rape),cv. Zhongshuang 10,,,leaf,group III histidine kinase,,,,reduced virulence,,,,,,,,reduced,,no,sodium dodecyl sulfate; Congo red; NaCl; glucose; sucrose; glycerol; hydrogen peroxide; dimethachlone,sodium dodecyl sulfate: CHEBI:8984; Congo red: CHEBI:34653; NaCl: CHEBI:26710; glucose: CHEBI:17234; sucrose: CHEBI:17992; glycerol: CHEBI:17754; hydrogen peroxide: CHEBI:16240; dimethachlone CAS no.: CAS:24096-53-5,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30070619,PubMed,10.1094/PHYTO-05-18-0156-R,Phytopathology. 2018 Aug 2,jianhl@mail.hzau.edu.cn,Overexpression of Sshk has a negative effect on the virulence of S. sclerotiorum and resulted in resistance to dimethachlone and increased sensitivity to various stresses and to the cell wall perturbing agents.,J Li 2018,2018,1 gene,Li-2018-Expression of the histidine kinase gen,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11811,PHI:8296,UniProt,J7M927,GenBank,BAM31080,,,M1 476,SIC,chromosome 1,,,,,,1314,Streptococcus pyogenes,,AP1,skin lesion,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen,streptococcal inhibitor of complement,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30002122,PubMed,10.1074/jbc.RA118.001988,J Biol Chem. 2018 Jul 12. pii: jbc.RA118.001988,Inga-Maria.Frick@med.lu.se,"The mutant SIC- strain displayed slightly enhanced virulence in the presence of plasminogen, again, in the absence of human plasminogen the SIC- strain was still more virulent as compared to the AP1 strain.",I M Frick 2018,2018,1 gene,Frick-2018-Streptococcal inhibitor of compleme,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11812,PHI:8297,UniProt,Q8GKS5,GenBank,AAN71715,,,H44/76,NalP,,rNalP S426A,,,,,487,Neisseria meningitidis,,MC58,meningococcal infection,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,neisserial autotransporter lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; other evidence: recombinant protein,,,YVS,30081080,PubMed,10.1016/j.micpath.2018.08.001,Microb Pathog. 2018 Aug 4;124:70-75,neil.oldfield@nottingham.ac.uk,"Uptake of proteolytically-active rNalP promoted an increase in HBMEC metabolic activity, whereas, abolition of proteolytic activity in rNalPS426A did not. rNalP proteolytic activity was not required for uptake or subsequent sub-cellular localization.",O A Dufailu 2018,2018,1 gene,Dufailu-2018-Uptake of Neisserial autotranspor,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11813,PHI:8297,UniProt,Q8GKS5,GenBank,AAN71715,,,H44/76,NalP,,,,,,,487,Neisseria meningitidis,,MC58,meningococcal infection,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,neisserial autotransporter lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,30081080,PubMed,10.1016/j.micpath.2018.08.001,Microb Pathog. 2018 Aug 4;124:70-75,neil.oldfield@nottingham.ac.uk,"Uptake of proteolytically-active rNalP promoted an increase in HBMEC metabolic activity, whereas, abolition of proteolytic activity in rNalPS426A did not. rNalP proteolytic activity was not required for uptake or subsequent sub-cellular localization.",O A Dufailu 2018,2018,1 gene,Dufailu-2018-Uptake of Neisserial autotranspor,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11814,PHI:8298,UniProt,O30916,GenBank,AAL20023,,,LT2,SopB,,C462S,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30010242,PubMed,10.1111/cmi.12938,Cell Microbiol. 2018 Jul 16:e12938,john.brumell@sickkids.ca,SopB mediates the recruitment of a subset of Rho family GTPases to invasion sites in a manner that requires its catalytic activity.,D Truong 2018,2018,1 gene,Truong-2018-Salmonella exploits host Rho GTPas,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11815,PHI:8298,UniProt,O30916,GenBank,AAL20023,,,LT2,SopB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30010242,PubMed,10.1111/cmi.12938,Cell Microbiol. 2018 Jul 16:e12938,john.brumell@sickkids.ca,SopB mediates the recruitment of a subset of Rho family GTPases to invasion sites in a manner that requires its catalytic activity.,D Truong 2018,2018,1 gene,Truong-2018-Salmonella exploits host Rho GTPas,BATCH_085A,2018-08-01,MC,,,,,,,,,,,,,
,,Record 11816,PHI:8299,UniProt,S0DVX0,GenBank,CCT65527,,,IMI 58289,SET1 (FFUJ_02475),FFUJ_chr03,,,,,,5127,Fusarium fujikuroi,1279085,IMI58289,bakanae,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,H3K4-specific histone methyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30047187,PubMed,10.1111/1462-2920.14339,Environ Microbiol. 2018 Jul 25,lena.studt@boku.ac.at,"The rice plants infected with ?set1, a strain that did not produce detectable GA3 levels during axenic growth, showed slightly chlorotic and extended internodes.",S Janevska 2018,2018,2 genes,Janevska-2018-Set1 and Kdm5 are antagonists fo,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11817,PHI:8300,UniProt,S0DWK6,GenBank,CCT66850,,,IMI 58289,KDM5 (FFUJ_13017),FFUJ_chr04,,,,,,5127,Fusarium fujikuroi,1279085,IMI58289,bakanae,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,Jumonji C demethylase,,,,unaffected pathogenicity,,,,,,increased,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30047187,PubMed,10.1111/1462-2920.14339,Environ Microbiol. 2018 Jul 25,lena.studt@boku.ac.at,"Both Δkdm5 and OE::KDM5 resulted in a WT-like phenotype, characterised by chlorotic and hyper-elongated rice internodes, albeit the significantly reduced GA3 levels found in Δkdm5 strains during axenic growth.",S Janevska 2018,2018,2 genes,Janevska-2018-Set1 and Kdm5 are antagonists fo,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11818,PHI:8300,UniProt,S0DWK6,GenBank,CCT66850,,,IMI 58289,KDM5 (FFUJ_13017),FFUJ_chr04,,,,,,5127,Fusarium fujikuroi,1279085,IMI58289,bakanae,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,Jumonji C demethylase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30047187,PubMed,10.1111/1462-2920.14339,Environ Microbiol. 2018 Jul 25,lena.studt@boku.ac.at,"Both Δkdm5 and OE::KDM5 resulted in a WT-like phenotype, characterised by chlorotic and hyper-elongated rice internodes, albeit the significantly reduced GA3 levels found in Δkdm5 strains during axenic growth.",S Janevska 2018,2018,2 genes,Janevska-2018-Set1 and Kdm5 are antagonists fo,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11819,PHI:8301,UniProt,P0A1B9,GenBank,AAL21774,,,LT2,invC,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,Salmonella pathogenicity island (SPI) 1 related protein; probable ATP synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30072981,PubMed,10.3389/fmicb.2018.01632,Front Microbiol. 2018 Jul 18;9:1632,dipa@iisc.ac.in,"SPI 1 mutants such as STM ΔinvC, ΔhilA and SPI 2 mutant ΔssaV were able to cross the blood-brain barrier. cortex; midbrain; cerebellum; medulla",D Chaudhuri 2018,2018,4 genes,Chaudhuri-2018-Salmonella Typhimurium Infectio,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11820,PHI:8302,UniProt,P43015,GenBank,AAD12579,,,SL1344,hilA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,Salmonella pathogenicity island (SPI) 1 related protein; transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30072981,PubMed,10.3389/fmicb.2018.01632,Front Microbiol. 2018 Jul 18;9:1632,dipa@iisc.ac.in,"SPI 1 mutants such as STM ΔinvC, ΔhilA and SPI 2 mutant ΔssaV were able to cross the blood-brain barrier. cortex; midbrain; cerebellum; medulla",D Chaudhuri 2018,2018,4 genes,Chaudhuri-2018-Salmonella Typhimurium Infectio,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11821,PHI:8303,UniProt,D0ZWU0,GenBank,ACY88188,,,14028S,ssaV,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,Salmonella pathogenicity island (SPI) 2 related protein; secretion system apparatus protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30072981,PubMed,10.3389/fmicb.2018.01632,Front Microbiol. 2018 Jul 18;9:1632,dipa@iisc.ac.in,"SPI 1 mutants such as STM ΔinvC, ΔhilA and SPI 2 mutant ΔssaV were able to cross the blood-brain barrier. cortex; midbrain; cerebellum; medulla",D Chaudhuri 2018,2018,4 genes,Chaudhuri-2018-Salmonella Typhimurium Infectio,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11822,PHI:8304,UniProt,P02936,GenBank,CAA26037,,,,ompA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; spleen; brain,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30072981,PubMed,10.3389/fmicb.2018.01632,Front Microbiol. 2018 Jul 18;9:1632,dipa@iisc.ac.in,"A reduction in bacterial burden was observed in the liver, spleen, cortex, cerebellum, midbrain and medulla of mice upon oral route infection of STM ΔompA mutant, however, upon intraperitoneal infection, a significant decrement in the bacterial concentration in mouse brain between wild-type S. Typhimurium and STM ΔompA was observed, whereas the bacterial concentrations were similar in liver and spleen. liver; spleen; cortex; midbrain; cerebellum; medulla",D Chaudhuri 2018,2018,4 genes,Chaudhuri-2018-Salmonella Typhimurium Infectio,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11823,PHI:8305,UniProt,Q5GZJ3,GenBank,xoo2624,,,,cheA2,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,chemotaxis auxiliary protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30011125,PubMed,10.1111/mpp.12718,Mol Plant Pathol. 2018 Jul 16,subhadeep@cdfd.org.in,Chemotaxis mutants and the fliC mutant exhibited significant deficiency in leaf entry and virulece compared to the wild type strain.,R K Verma 2018,2018,6 genes,Verma-2018-Xanthomonas oryzae pv. oryzae chemo,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11824,PHI:8306,UniProt,Q5GYW0,GenBank,xoo2857,,,,cheR2,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,chemotaxis auxiliary protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30011125,PubMed,10.1111/mpp.12718,Mol Plant Pathol. 2018 Jul 16,subhadeep@cdfd.org.in,Chemotaxis mutants and the fliC mutant exhibited significant deficiency in leaf entry and virulece compared to the wild type strain.,R K Verma 2018,2018,6 genes,Verma-2018-Xanthomonas oryzae pv. oryzae chemo,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11825,PHI:8307,UniProt,Q5GYY4,GenBank,xoo2833,,,,cheW2,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,chemotaxis auxiliary protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30011125,PubMed,10.1111/mpp.12718,Mol Plant Pathol. 2018 Jul 16,subhadeep@cdfd.org.in,Chemotaxis mutants and the fliC mutant exhibited significant deficiency in leaf entry and virulece compared to the wild type strain.,R K Verma 2018,2018,6 genes,Verma-2018-Xanthomonas oryzae pv. oryzae chemo,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11826,PHI:8308,UniProt,Q5GZJ5,GenBank,xoo2622,,,,cheY1,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,chemotaxis auxiliary protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30011125,PubMed,10.1111/mpp.12718,Mol Plant Pathol. 2018 Jul 16,subhadeep@cdfd.org.in,Chemotaxis mutants and the fliC mutant exhibited significant deficiency in leaf entry and virulece compared to the wild type strain.,R K Verma 2018,2018,6 genes,Verma-2018-Xanthomonas oryzae pv. oryzae chemo,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11827,PHI:8309,UniProt,Q5GYW9,GenBank,AAW76102,,,KACC10331,mcp2 (XOO2848),,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,chemoreceptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30011125,PubMed,10.1111/mpp.12718,Mol Plant Pathol. 2018 Jul 16,subhadeep@cdfd.org.in,"Chemoreceptor Mcp2 was involved in sensing xylem sap and constituents of xylem exudate including methionine, serine and histidine, and played an important role in epiphytic entry and virulence.",R K Verma 2018,2018,6 genes,Verma-2018-Xanthomonas oryzae pv. oryzae chemo,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11828,PHI:8310,UniProt,Q5GZN6,GenBank,AAW75835,,,KACC10331,fliC (XOO2581),,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,non motile flagella,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30011125,PubMed,10.1111/mpp.12718,Mol Plant Pathol. 2018 Jul 16,subhadeep@cdfd.org.in,Chemotaxis mutants and the fliC mutant exhibited significant deficiency in leaf entry and virulece compared to the wild type strain.,R K Verma 2018,2018,6 genes,Verma-2018-Xanthomonas oryzae pv. oryzae chemo,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11829,PHI:8311,,no data found,,,,,,TLObeta2,,,,,,,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,telomere-associated protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,other evidence: heterologous expression,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11830,PHI:8312,,no data found,,,,,,TLOgamma11,,,,,,,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,telomere-associated protein,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,other evidence: heterologous expression,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11831,PHI:8313,,no data found,,,,,,TLOalpha12,,,,,,,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,telomere-associated protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,other evidence: heterologous expression,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11832,PHI:8314,UniProt,B9WKI2,GenBank,CAX40836,,,CD36,tlo1,chromosome 7,,,,,PHI:8315,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11833,PHI:8315,UniProt,B9WN82,GenBank,CAX40549,,,CD36,tlo2,chromosome R,,,,,PHI:8314,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11834,PHI:8314,UniProt,B9WKI2,GenBank,CAX40836,,,CD36,tlo1,chromosome 7,,,,,PHI:8315; PHI:8316,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11835,PHI:8315,UniProt,B9WN82,GenBank,CAX40549,,,CD36,tlo2,chromosome R,,,,,PHI:8314; PHI:8316,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11836,PHI:8316,,no data found,,,,,,TLOalpha1,,,,,,PHI:8314; PHI:8315,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,telomere-associated protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,other evidence: heterologous expression,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11837,PHI:8314,UniProt,B9WKI2,GenBank,CAX40836,,,CD36,tlo1,chromosome 7,,,,,PHI:8315; PHI:8317,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11838,PHI:8315,UniProt,B9WN82,GenBank,CAX40549,,,CD36,tlo2,chromosome R,,,,,PHI:8314; PHI:8317,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11839,PHI:8317,,no data found,,,,,,TLOalpha3,,,,,,PHI:8314; PHI:8315,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,telomere-associated protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,other evidence: heterologous expression,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11840,PHI:8314,UniProt,B9WKI2,GenBank,CAX40836,,,CD36,tlo1,chromosome 7,,,,,PHI:8315; PHI:8318,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11841,PHI:8315,UniProt,B9WN82,GenBank,CAX40549,,,CD36,tlo2,chromosome R,,,,,PHI:8314; PHI:8318,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11842,PHI:8318,,no data found,,,,,,TLOalpha9,,,,,,PHI:8314; PHI:8315,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,telomere-associated protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,other evidence: heterologous expression,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11843,PHI:8314,UniProt,B9WKI2,GenBank,CAX40836,,,CD36,tlo1,chromosome 7,,,,,PHI:8315; PHI:8313,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11844,PHI:8315,UniProt,B9WN82,GenBank,CAX40549,,,CD36,tlo2,chromosome R,,,,,PHI:8314; PHI:8313,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11845,PHI:8313,,no data found,,,,,,TLOalpha12,,,,,,PHI:8314; PHI:8315,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,telomere-associated protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,other evidence: heterologous expression,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11846,PHI:8314,UniProt,B9WKI2,GenBank,CAX40836,,,CD36,tlo1,chromosome 7,,,,,PHI:8315; PHI:8319,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11847,PHI:8315,UniProt,B9WN82,GenBank,CAX40549,,,CD36,tlo2,chromosome R,,,,,PHI:8314; PHI:8319,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11848,PHI:8319,,no data found,,,,,,TLOgamma7,,,,,,PHI:8314; PHI:8315,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,telomere-associated protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,other evidence: heterologous expression,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11849,PHI:8314,UniProt,B9WKI2,GenBank,CAX40836,,,CD36,tlo1,chromosome 7,,,,,PHI:8315; PHI:8312,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11850,PHI:8315,UniProt,B9WN82,GenBank,CAX40549,,,CD36,tlo2,chromosome R,,,,,PHI:8314; PHI:8312,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"transcriptional activator, putative",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11851,PHI:8312,,no data found,,,,,,TLOgamma11,,,,,,PHI:8314; PHI:8315,42374,Candida dubliniensis,,Wü284,erythematous candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,telomere-associated protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,other evidence: heterologous expression,,,YVS,30028853,PubMed,10.1371/journal.pone.0200852,PLoS One. 2018 Jul 20;13(7):e0200852,Gary.Moran@dental.tcd.ie,Data showed that expansion of the TLO gene family in C. dubliniensis resulted in gain of function and that there was functional diversity amongst members of the gene family.,P R Flanagan 2018,2018,9 genes,Flanagan-2018-Expansion of the TLO gene family,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11852,PHI:8320,UniProt,B5R9L9,GenBank,CAR40068,,,287/91,idnT,,,,,,,28901,Salmonella enterica,550538,subsp. enterica serovar Gallinarum strain 287/91,fowl typhoid,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen,l-ido transporter,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30028856,PubMed,10.1371/journal.pone.0200585,PLoS One. 2018 Jul 20;13(7):e0200585,oliveirocaetano@yahoo.com.br,"Infection of chickens with idnTO mutants led to increased numbers of bacteria in the livers and spleens at 5 days post-infection, but with slightly decreased heterophil infiltration in the spleens when compared to the wild-type strain.",D F Alves Batista 2018,2018,3 genes,Alves Batista-2018-Evaluation of pathogenicity,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11853,PHI:8321,UniProt,B5R9M0,GenBank,CAR40069,,,287/91,idnO,,,,,,,28901,Salmonella enterica,550538,subsp. enterica serovar Gallinarum strain 287/91,fowl typhoid,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen,gluconate 5-dehydrogenase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30028856,PubMed,10.1371/journal.pone.0200585,PLoS One. 2018 Jul 20;13(7):e0200585,oliveirocaetano@yahoo.com.br,"Infection of chickens with idnTO mutants led to increased numbers of bacteria in the livers and spleens at 5 days post-infection, but with slightly decreased heterophil infiltration in the spleens when compared to the wild-type strain.",D F Alves Batista 2018,2018,3 genes,Alves Batista-2018-Evaluation of pathogenicity,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11854,PHI:8322,UniProt,B5RC73,GenBank,CAR38107,,,287/91,ccmH,,,,,,,28901,Salmonella enterica,550538,subsp. enterica serovar Gallinarum strain 287/91,fowl typhoid,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen,cytochrome c-type biogenesis protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30028856,PubMed,10.1371/journal.pone.0200585,PLoS One. 2018 Jul 20;13(7):e0200585,oliveirocaetano@yahoo.com.br,No significant phenotypic change was caused by mutation to ccmH genes.,D F Alves Batista 2018,2018,3 genes,Alves Batista-2018-Evaluation of pathogenicity,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11855,PHI:8320,UniProt,B5R9L9,GenBank,CAR40068,,,287/91,idnT,,,,,,,28901,Salmonella enterica,550538,subsp. enterica serovar Gallinarum strain 287/91,fowl typhoid,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen,l-ido transporter,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30028856,PubMed,10.1371/journal.pone.0200585,PLoS One. 2018 Jul 20;13(7):e0200585,oliveirocaetano@yahoo.com.br,"Infection of chickens with idnTO mutants led to increased numbers of bacteria in the livers and spleens at 5 days post-infection, but with slightly decreased heterophil infiltration in the spleens when compared to the wild-type strain.",D F Alves Batista 2018,2018,3 genes,Alves Batista-2018-Evaluation of pathogenicity,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11856,PHI:8321,UniProt,B5R9M0,GenBank,CAR40069,,,287/91,idnO,,,,,,,28901,Salmonella enterica,550538,subsp. enterica serovar Gallinarum strain 287/91,fowl typhoid,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen,gluconate 5-dehydrogenase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30028856,PubMed,10.1371/journal.pone.0200585,PLoS One. 2018 Jul 20;13(7):e0200585,oliveirocaetano@yahoo.com.br,"Infection of chickens with idnTO mutants led to increased numbers of bacteria in the livers and spleens at 5 days post-infection, but with slightly decreased heterophil infiltration in the spleens when compared to the wild-type strain.",D F Alves Batista 2018,2018,3 genes,Alves Batista-2018-Evaluation of pathogenicity,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11857,PHI:8322,UniProt,B5RC73,GenBank,CAR38107,,,287/91,ccmH,,,,,,,28901,Salmonella enterica,550538,subsp. enterica serovar Gallinarum strain 287/91,fowl typhoid,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen,cytochrome c-type biogenesis protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30028856,PubMed,10.1371/journal.pone.0200585,PLoS One. 2018 Jul 20;13(7):e0200585,oliveirocaetano@yahoo.com.br,No significant phenotypic change was caused by mutation to ccmH genes.,D F Alves Batista 2018,2018,3 genes,Alves Batista-2018-Evaluation of pathogenicity,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11858,PHI:8323,UniProt,B8N558,GenBank,EED54844,,,NRRL3357,crpA (AFLA_020960),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,Cu ATPase transporter,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,menadione; hydrogen peroxide,menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30027796,PubMed,10.1080/21505594.2018.1496774,Virulence. 2018;9(1):1273-1286,npkeller@wisc.edu,"Compared to wild type, the mutants were impaired in the ability to colonize maize seed treated with Cu fungicide but showed no difference in virulence on non-treated seed.",K Yang 2018,2018,3 genes,Yang-2018-Contribution of ATPase copper transp,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11859,PHI:8324,UniProt,B8NT64,GenBank,EED47292,,,NRRL3357,crpB (AFLA_053470),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,Cu ATPase transporter,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,menadione; hydrogen peroxide,menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30027796,PubMed,10.1080/21505594.2018.1496774,Virulence. 2018;9(1):1273-1286,npkeller@wisc.edu,"Compared to wild type, the mutants were impaired in the ability to colonize maize seed treated with Cu fungicide but showed no difference in virulence on non-treated seed.",K Yang 2018,2018,3 genes,Yang-2018-Contribution of ATPase copper transp,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11860,PHI:8323,UniProt,B8N558,GenBank,EED54844,,,NRRL3357,crpA (AFLA_020960),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,Cu ATPase transporter,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,menadione; hydrogen peroxide,menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30027796,PubMed,10.1080/21505594.2018.1496774,Virulence. 2018;9(1):1273-1286,npkeller@wisc.edu,"Compared to wild type, the mutants were impaired in the ability to colonize maize seed treated with Cu fungicide but showed no difference in virulence on non-treated seed.",K Yang 2018,2018,3 genes,Yang-2018-Contribution of ATPase copper transp,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11861,PHI:8324,UniProt,B8NT64,GenBank,EED47292,,,NRRL3357,crpB (AFLA_053470),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,Cu ATPase transporter,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,menadione; hydrogen peroxide,menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30027796,PubMed,10.1080/21505594.2018.1496774,Virulence. 2018;9(1):1273-1286,npkeller@wisc.edu,"Compared to wild type, the mutants were impaired in the ability to colonize maize seed treated with Cu fungicide but showed no difference in virulence on non-treated seed.",K Yang 2018,2018,3 genes,Yang-2018-Contribution of ATPase copper transp,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11862,PHI:8325,UniProt,B8N2G1,GenBank,EED56374,,,NRRL3357,aceA (AFLA_036460),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,Cu-fist DNA binding protien,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,menadione; hydrogen peroxide,menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30027796,PubMed,10.1080/21505594.2018.1496774,Virulence. 2018;9(1):1273-1286,npkeller@wisc.edu,"Compared to wild type, the mutants were impaired in the ability to colonize maize seed treated with Cu fungicide but showed no difference in virulence on non-treated seed.",K Yang 2018,2018,3 genes,Yang-2018-Contribution of ATPase copper transp,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11863,PHI:8323,UniProt,B8N558,GenBank,EED54844,,,NRRL3357,crpA (AFLA_020960),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,invasive aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,Cu ATPase transporter,,,,reduced virulence,,,,,,,,reduced,,no,menadione; hydrogen peroxide,menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30027796,PubMed,10.1080/21505594.2018.1496774,Virulence. 2018;9(1):1273-1286,npkeller@wisc.edu,"A mouse model of invasive aspergillosis showed ΔcrpAΔcrpB and to a lesser degree ΔaceA to be significantly reduced in virulence, following the greater sensitivity of ΔcrpAΔcrpB to Cu than ΔaceA.",K Yang 2018,2018,3 genes,Yang-2018-Contribution of ATPase copper transp,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11864,PHI:8324,UniProt,B8NT64,GenBank,EED47292,,,NRRL3357,crpB (AFLA_053470),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,invasive aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,Cu ATPase transporter,,,,reduced virulence,,,,,,,,reduced,,no,menadione; hydrogen peroxide,menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30027796,PubMed,10.1080/21505594.2018.1496774,Virulence. 2018;9(1):1273-1286,npkeller@wisc.edu,"A mouse model of invasive aspergillosis showed ΔcrpAΔcrpB and to a lesser degree ΔaceA to be significantly reduced in virulence, following the greater sensitivity of ΔcrpAΔcrpB to Cu than ΔaceA.",K Yang 2018,2018,3 genes,Yang-2018-Contribution of ATPase copper transp,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11865,PHI:8325,UniProt,B8N2G1,GenBank,EED56374,,,NRRL3357,aceA (AFLA_036460),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,invasive aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,Cu-fist DNA binding protien,,,,unaffected pathogenicity,,,,,,,,reduced,,no,menadione; hydrogen peroxide,menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30027796,PubMed,10.1080/21505594.2018.1496774,Virulence. 2018;9(1):1273-1286,npkeller@wisc.edu,"A mouse model of invasive aspergillosis showed ΔcrpAΔcrpB and to a lesser degree ΔaceA to be significantly reduced in virulence, following the greater sensitivity of ΔcrpAΔcrpB to Cu than ΔaceA.",K Yang 2018,2018,3 genes,Yang-2018-Contribution of ATPase copper transp,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11866,PHI:8326,UniProt,Q48BD8,GenBank,AAZ37975,,,1448A; BAA-978,PphHopQ1,,,,,,PHI:8327,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11867,PHI:8327,UniProt,Q48Q39,GenBank,AAZ37024,,,1448A; BAA-978,PphHopR1,,,,,,PHI:8326,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11868,PHI:8326,UniProt,Q48BD8,GenBank,AAZ37975,,,1448A; BAA-978,PphHopQ1,,,,,,PHI:8328,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11869,PHI:8328,UniProt,Q888Y1,GenBank,AAO54417,,,DC3000,PtoHopR1,,,,,,PHI:8326,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11870,PHI:8329,UniProt,Q888Y7,GenBank,AAO54411,,,DC3000,PtoHopQ1,,,,,,PHI:8327,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11871,PHI:8327,UniProt,Q48Q39,GenBank,AAZ37024,,,1448A; BAA-978,PphHopR1,,,,,,PHI:8329,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11872,PHI:8329,UniProt,Q888Y7,GenBank,AAO54411,,,DC3000,PtoHopQ1,,,,,,PHI:8328,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11873,PHI:8328,UniProt,Q888Y1,GenBank,AAO54417,,,1448A; BAA-978,PtoHopR1,,,,,,PHI:8329,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11874,PHI:8326,UniProt,Q48BD8,GenBank,AAZ37975,,,1448A; BAA-978,PphHopQ1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11875,PHI:8327,UniProt,Q48Q39,GenBank,AAZ37024,,,1448A; BAA-978,PphHopR1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11876,PHI:8329,UniProt,Q888Y7,GenBank,AAO54411,,,DC3000,PtoHopQ1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11877,PHI:8328,UniProt,Q888Y1,GenBank,AAO54417,,,1448A; BAA-978,PtoHopR1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11878,PHI:8326,UniProt,Q48BD8,GenBank,AAZ37975,,,1448A; BAA-978,PphHopQ1,,,,,,PHI:8327,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11879,PHI:8327,UniProt,Q48Q39,GenBank,AAZ37024,,,1448A; BAA-978,PphHopR1,,,,,,PHI:8326,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11880,PHI:8326,UniProt,Q48BD8,GenBank,AAZ37975,,,1448A; BAA-978,PphHopQ1,,,,,,PHI:8328,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11881,PHI:8328,UniProt,Q888Y1,GenBank,AAO54417,,,1448A; BAA-978,PtoHopR1,,,,,,PHI:8326,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11882,PHI:8329,UniProt,Q888Y7,GenBank,AAO54411,,,DC3000,PtoHopQ1,,,,,,PHI:8327,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11883,PHI:8327,UniProt,Q48Q39,GenBank,AAZ37024,,,1448A; BAA-978,PphHopR1,,,,,,PHI:8329,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11884,PHI:8329,UniProt,Q888Y7,GenBank,AAO54411,,,DC3000,PtoHopQ1,,,,,,PHI:8328,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11885,PHI:8328,UniProt,Q888Y1,GenBank,AAO54417,,,1448A; BAA-978,PtoHopR1,,,,,,PHI:8329,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,30042777,PubMed,10.3389/fpls.2018.00978,Front Plant Sci. 2018 Jul 10;9:978,krzyma@ibb.waw.pl,"Substitutions at these two positions did not strongly affect PtoHopQ1 virulence properties in a susceptible host but they reduced bacterial growth and accelerated onset of cell death in a resistant host, suggesting that N-terminal mutations rendered PtoHopQ1 susceptible to processing in planta and, thus, represent a mechanism of recognition avoidance.",P Zembek 2018,2018,4 genes,Zembek-2018-Two Strategies of Pseudomonas syri,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11886,PHI:8330,UniProt,P0A0I5,GenBank,BAB43126,,,N315,agrA,,,,,,,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,virulence gene transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30028663,PubMed,10.1099/mic.0.000695,Microbiology. 2018 Jul 20,s.r.wig@imperial.ac.uk,"Disruption of the master regulator of the agr operon, agrA, led to decrease in S. aureus survival compared to the wildtype strain following 6h incubation in whole human blood.",A Krishna 2018,2018,2 genes,Krishna-2018-Naturally occurring polymorphisms,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11887,PHI:8331,,no data found,,,,,,rsp,,,,,,,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,virulence regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30028663,PubMed,10.1099/mic.0.000695,Microbiology. 2018 Jul 20,s.r.wig@imperial.ac.uk,"Although transposon disruption of rsp resulted in a reduction in agr expression, no corresponding decrease in S. aureus survival was observed.",A Krishna 2018,2018,2 genes,Krishna-2018-Naturally occurring polymorphisms,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11888,PHI:8331,,no data found,,,,,,rsp,,D42STOP; G61D; G84D; K116STOP; S178A; A204V; E313STOP; E378STOP; R456H; P566STOP; Q652del,,,,,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,virulence regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30028663,PubMed,10.1099/mic.0.000695,Microbiology. 2018 Jul 20,s.r.wig@imperial.ac.uk,Loss of function mutations in rsp did not significantly alter S. aureus survival in blood.,A Krishna 2018,2018,2 genes,Krishna-2018-Naturally occurring polymorphisms,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11889,PHI:8331,,no data found,,,,,,rsp,,D103N; G115E; A130V; H474L; D530G; D530Y; V615A; D103N and P626L,,,,,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,virulence regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30028663,PubMed,10.1099/mic.0.000695,Microbiology. 2018 Jul 20,s.r.wig@imperial.ac.uk,Rsp mutations that enhanced agr operon expression were found to significantly improve S. aureus survival following 6h incubation in blood.,A Krishna 2018,2018,2 genes,Krishna-2018-Naturally occurring polymorphisms,BATCH_085B,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11890,PHI:8332,UniProt,F9X894,GenBank,EGP87880,,,IPO323,ZtAbaA,chromosome 4,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu80,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30154771,PubMed,10.3389/fmicb.2018.01859,Front Microbiol. 2018 Aug 14;9:1859,andy.bailey@bristol.ac.uk,"ZtStuA gene was a key regulator of asexual reproduction in Z. tritici which controled initiation of pycnidia development, ZtFlbC and ZtBrlA2 genes were downstream regulators which regulated pycnidia and pycnidiospore production.",A M M Tiley 2018,2018,6 genes,Tiley-2018-Exploring the Genetic Regulation of,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11891,PHI:8333,UniProt,F9WY21,GenBank,EGP91356,,,IPO323,ZtBrlA1,chromosome 1,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu80,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30154771,PubMed,10.3389/fmicb.2018.01859,Front Microbiol. 2018 Aug 14;9:1859,andy.bailey@bristol.ac.uk,"ZtStuA gene was a key regulator of asexual reproduction in Z. tritici which controled initiation of pycnidia development, ZtFlbC and ZtBrlA2 genes were downstream regulators which regulated pycnidia and pycnidiospore production.",A M M Tiley 2018,2018,6 genes,Tiley-2018-Exploring the Genetic Regulation of,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11892,PHI:8334,UniProt,F9X0G7,GenBank,EGP91539,,,IPO323,ZtFlbB,chromosome 1,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu80,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30154771,PubMed,10.3389/fmicb.2018.01859,Front Microbiol. 2018 Aug 14;9:1859,andy.bailey@bristol.ac.uk,"ZtStuA gene was a key regulator of asexual reproduction in Z. tritici which controled initiation of pycnidia development, ZtFlbC and ZtBrlA2 genes were downstream regulators which regulated pycnidia and pycnidiospore production.",A M M Tiley 2018,2018,6 genes,Tiley-2018-Exploring the Genetic Regulation of,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11893,PHI:8335,UniProt,F9XB35,GenBank,EGP87412,,,IPO323,ZtFlbC,chromosome 5,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu80,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30154771,PubMed,10.3389/fmicb.2018.01859,Front Microbiol. 2018 Aug 14;9:1859,andy.bailey@bristol.ac.uk,"ZtStuA gene was a key regulator of asexual reproduction in Z. tritici which controled initiation of pycnidia development, ZtFlbC and ZtBrlA2 genes were downstream regulators which regulated pycnidia and pycnidiospore production.",A M M Tiley 2018,2018,6 genes,Tiley-2018-Exploring the Genetic Regulation of,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11894,PHI:8336,UniProt,F9XGX4,GenBank,EGP84931,,,IPO323,ZtBrlA2,chromosome 8,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu80,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,transcription factor,,,,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30154771,PubMed,10.3389/fmicb.2018.01859,Front Microbiol. 2018 Aug 14;9:1859,andy.bailey@bristol.ac.uk,"ZtStuA gene was a key regulator of asexual reproduction in Z. tritici which controled initiation of pycnidia development, ZtFlbC and ZtBrlA2 genes were downstream regulators which regulated pycnidia and pycnidiospore production.",A M M Tiley 2018,2018,6 genes,Tiley-2018-Exploring the Genetic Regulation of,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11895,PHI:8337,UniProt,F9XD62,GenBank,EGP86429,,,IPO323,ZtstuA,chromosome 6,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu80,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30154771,PubMed,10.3389/fmicb.2018.01859,Front Microbiol. 2018 Aug 14;9:1859,andy.bailey@bristol.ac.uk,"ZtStuA gene was a key regulator of asexual reproduction in Z. tritici which controled initiation of pycnidia development, ZtFlbC and ZtBrlA2 genes were downstream regulators which regulated pycnidia and pycnidiospore production.",A M M Tiley 2018,2018,6 genes,Tiley-2018-Exploring the Genetic Regulation of,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11896,PHI:8338,,no data found,,,,,,Myo5,,,,,,,282267,Fusarium asiaticum,,FaJT041,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Huaimai 33,,,leaf,myosin,,,,reduced virulence,,,,,,,,,,no,tebuconazole; prochloraz; azoxystrobin; carbendazim; phenamacril,"tebuconazole: CHEBI:81781; prochloraz: CHEBI:8434; azoxystrobin: CHEBI:40909, CAS:131860-33-8; carbendazim: CHEBI:3392, CAS:10605-21-7; phenamacril: CAS:3336-69-4",,,,,altered gene expression / gene regulation: silencing: gene complementation,,,YVS,30195381,PubMed,10.1016/j.pestbp.2018.07.004,Pestic Biochem Physiol. 2018 Sep;150:1-9,mgzhou@njau.edu.cn,Myo5 dsRNA increased the sensitivity of the fungus to phenamacril and effected more effective mixing with phenamacril on living plants.,X S Song 2018,2018,1 gene,Song-2018-A myosin5 dsRNA that reduces the fun,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11897,PHI:8339,UniProt,C0NNW1,GenBank,EEH06621,,,G186AR,afp1,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,APSES-family transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,congo red; SDS; fluconazole; H2O2; NaCl,"congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; fluconazole: CHEBI:46081, CAS:86386-73-4; H2O2: CHEBI:16240; NaCl: CHEBI:26710",,,,,altered gene expression / gene regulation: silencing: gene complementation,,,YVS,30101348,PubMed,10.1093/femsyr/foy087,FEMS Yeast Res. 2018 Dec 1;18(8),rappleye.1@osu.edu,"The APSES-family transcription factors were not individually required for H. capsulatum infection of cultured macrophages or murine infection, nor did any contribute significantly to resistance to cellular stresses including cell wall perturbation, osmotic stress, oxidative stress or antifungal treatment.",L V G Longo 2018,2018,4 genes,Longo-2018-Characterization of the APSES-famil,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11898,PHI:8340,UniProt,C0NMA8,GenBank,EEH07759,,,G186AR,stu1,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,APSES-family transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,congo red; SDS; fluconazole; H2O2; NaCl,"congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; fluconazole: CHEBI:46081, CAS:86386-73-4; H2O2: CHEBI:16240; NaCl: CHEBI:26710",,,,,altered gene expression / gene regulation: silencing: gene complementation,,,YVS,30101348,PubMed,10.1093/femsyr/foy087,FEMS Yeast Res. 2018 Dec 1;18(8),rappleye.1@osu.edu,"The APSES-family transcription factors were not individually required for H. capsulatum infection of cultured macrophages or murine infection, nor did any contribute significantly to resistance to cellular stresses including cell wall perturbation, osmotic stress, oxidative stress or antifungal treatment.",L V G Longo 2018,2018,4 genes,Longo-2018-Characterization of the APSES-famil,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11899,PHI:8341,UniProt,C0NX15,GenBank,EEH03881,,,G186AR,xbp1,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,APSES-family transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,congo red; SDS; fluconazole; H2O2; NaCl,"congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; fluconazole: CHEBI:46081, CAS:86386-73-4; H2O2: CHEBI:16240; NaCl: CHEBI:26710",,,,,altered gene expression / gene regulation: silencing: gene complementation,,,YVS,30101348,PubMed,10.1093/femsyr/foy087,FEMS Yeast Res. 2018 Dec 1;18(8),rappleye.1@osu.edu,"The APSES-family transcription factors were not individually required for H. capsulatum infection of cultured macrophages or murine infection, nor did any contribute significantly to resistance to cellular stresses including cell wall perturbation, osmotic stress, oxidative stress or antifungal treatment.",L V G Longo 2018,2018,4 genes,Longo-2018-Characterization of the APSES-famil,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11900,PHI:8342,UniProt,C0NDI1,GenBank,EEH11722,,,G186AR,swi6,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,APSES-family transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,congo red; SDS; fluconazole; H2O2; NaCl,"congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; fluconazole: CHEBI:46081, CAS:86386-73-4; H2O2: CHEBI:16240; NaCl: CHEBI:26710",,,,,altered gene expression / gene regulation: silencing: gene complementation,,,YVS,30101348,PubMed,10.1093/femsyr/foy087,FEMS Yeast Res. 2018 Dec 1;18(8),rappleye.1@osu.edu,"The APSES-family transcription factors were not individually required for H. capsulatum infection of cultured macrophages or murine infection, nor did any contribute significantly to resistance to cellular stresses including cell wall perturbation, osmotic stress, oxidative stress or antifungal treatment.",L V G Longo 2018,2018,4 genes,Longo-2018-Characterization of the APSES-famil,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11901,PHI:8343,UniProt,S7UG79,GenBank,EPR56847,,,GT1,GRA11 (TGGT1_212410),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11902,PHI:8344,UniProt,S7UMP6,GenBank,EPR59251,,,GT1,GRA12 (TGGT1_275850),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11903,PHI:8345,UniProt,S7UHI7,GenBank,EPR57170,,,GT1,GRA13 (TGGT1_237880),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11904,PHI:8346,UniProt,A0A125YJW1,GenBank,EPR60447,,,GT1,GRA14 (TGGT1_239740),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,dense granule protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11905,PHI:8347,UniProt,S7WHF1,GenBank,EPR63758,,,GT1,GRA20 (TGGT1_200010),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11906,PHI:8348,UniProt,S7UG61,GenBank,EPR56827,,,GT1,GRA21 (TGGT1_241610),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11907,PHI:8349,UniProt,S7WBR2,GenBank,EPR64284,,,GT1,GRA28 (TGGT1_231960),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative omega secalin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11908,PHI:8350,UniProt,S7V563,GenBank,EPR64817,,,GT1,GRA29 (TGGT1_269690),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11909,PHI:8351,UniProt,S7V2P3,GenBank,EPR64276,,,GT1,GRA30 (TGGT1_232000),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11910,PHI:8352,UniProt,S7UH01,GenBank,EPR57052,,,GT1,GRA31 (TGGT1_220240),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11911,PHI:8353,UniProt,S7V110,GenBank,EPR63665,,,GT1,GRA33 (TGGT1_247440),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11912,PHI:8354,UniProt,S7UV87,GenBank,EPR61670,,,GT1,GRA34 (TGGT1_203290),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11913,PHI:8355,UniProt,S7W5P1,GenBank,EPR62264,,,GT1,GRA35 (TGGT1_226380),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11914,PHI:8356,UniProt,S7UPB4,GenBank,EPR59512,,,GT1,GRA36 (TGGT1_213067),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11915,PHI:8357,UniProt,A0A125YNW9,GenBank,EPR60246,,,GT1,GRA37 (TGGT1_236890),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11916,PHI:8358,UniProt,S7USQ4,GenBank,EPR61031,,,GT1,GRA38 (TGGT1_312420),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11917,PHI:8359,UniProt,S7V1U8,GenBank,EPR63970,,,GT1,GRA40 (TGGT1_219810),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30211128,PubMed,10.3389/fcimb.2018.00300,Front Cell Infect Microbiol. 2018 Aug 28;8:300,xingquanzhu1@hotmail.com,Targeted deletion of these 17 GRA genes had no significant effect neither on the in vitro growth and egress of the mutant strains from the host cells nor on the parasite virulence in the mouse model of infection.,M J Bai 2018,2018,17 genes,Bai-2018-Functional Characterization of Dense,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11918,PHI:8360,UniProt,G2X4E0,GenBank,EGY23584,,,VdLs.17,VdHapX (VDAG_05022),chromosome 4,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,292731,Cotinus obovatus (no common name found),,,,seedling,bZip transcription factor,,,,reduced virulence,,,yes,,,,,reduced; aberrant,,no,bathophenanthroline disulfonate; H2O2,bathophenanthroline disulfonate: CHEBI:78158; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30185514,PubMed,10.1128/mSphere.00400-18,mSphere. 2018 Sep 5;3(5). pii: e00400-18,ylwang@bjfu.edu.cn,Deletion of VdHapX impaired mycelial growth and conidiation under both iron starvation and iron sufficiency.,Y Wang 2018,2018,1 gene,Wang-2018-The Transcription Factor VdHapX Cont,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11919,PHI:8361,UniProt,P0C0F7,GenBank,CAB89845,,,,rpfC (XC_2333),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,histidine kinase sensor in the two component regulatory system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30176800,PubMed,10.1186/s12866-018-1233-5,BMC Microbiol. 2018 Sep 3;18(1):103,jltang@gxu.edu.cn,RpfC regulates the expression of hrpX in the minimal medium XCM1 as well as in the host plant Chinese radish and influences significantly the expression of hrpG in the host plant tissues.,B L Jiang 2018,2018,1 gene,Jiang-2018-RpfC regulates the expression of th,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11920,PHI:8362,,no data found,,,,,,cigR,,,,,,,28901,Salmonella enterica,604,subsp. enterica serovar Pullorum strain C79-13,pullorum disease,birds,9031,Gallus gallus (related: chicken),Hy-line,,,,T3SS2 effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30173754,PubMed,10.1016/j.vetmic.2018.07.013,Vet Microbiol. 2018 Sep;223:65-71,jiao@yzu.edu.cn,"The deletion of cigR in S. Typhimurium and S. Pullorum enhanced bacterial virulence to both mice and chickens. In addition, infection and proliferation of strain C79-13ΔcigR in the avian macrophage cell line HD-11 and murine macrophages RAW264.7 was higher than that of the wild type strain.",Q Li 2018,2018,1 gene,Li-2018-Salmonella-containing vacuole developm,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11921,PHI:8362,UniProt,H9L434,GenBank,AAL22620,,,LT2,cigR,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,T3SS2 effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30173754,PubMed,10.1016/j.vetmic.2018.07.013,Vet Microbiol. 2018 Sep;223:65-71,jiao@yzu.edu.cn,"The deletion of cigR in S. Typhimurium and S. Pullorum enhanced bacterial virulence to both mice and chickens. In addition, infection and proliferation of strain C79-13ΔcigR in the avian macrophage cell line HD-11 and murine macrophages RAW264.7 was higher than that of the wild type strain.",Q Li 2018,2018,1 gene,Li-2018-Salmonella-containing vacuole developm,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11922,PHI:8363,UniProt,Q8ZQ79,GenBank,AF236075_3,,,14028s,SseI,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,SPI-2 effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30102745,PubMed,10.1371/journal.ppat.1007248,PLoS Pathog. 2018 Aug 13;14(8):e1007248,klaus.aktories@pharmakol.uni-freiburg.de,"Cell viability measured by the metabolic capacity of the cells, was increased after infection with wt-Salmonella as compared to ΔsseI-infected cells.",T Brink 2018,2018,1 gene,Brink-2018-Salmonella Typhimurium effector Sse,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11923,PHI:8364,UniProt,Q1WEM6,GenBank,ABC70473,,,Ea1189,AvrRpt2EA,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Pinova,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30204065,PubMed,10.1094/MPMI-12-17-0300-R,Mol Plant Microbe Interact. 2018 Sep 11:MPMI12170300R,henryk.flachowsky@julius-kuehn.de,Induced expression of AvrRpt2EA led to shoot necrosis and browning of older leaves.,S Schröpfer 2018,2018,1 gene,"Schropfer-2018-A Single Effector Protein, AvrR",BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11924,PHI:8365,UniProt,I1S071,GenBank,CEF75431,,,PH-1,FGSG_10089,chromosome 1,,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,flower,GPI-anchored cell wall protein,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30113774,PubMed,10.1111/mpp.12742,Mol Plant Pathol. 2018 Aug 16,Rajagopal.subramaniam@agr.gc.ca,Cys325 was necessary to cause disease and contribute to overall virulence function of the FGSG_10089 protein.,U Fernando 2018,2018,5 genes,Fernando-2018-Redox signalling from NADPH oxid,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11925,PHI:8365,UniProt,I1S071,GenBank,CEF75431,,,PH-1,FGSG_10089,chromosome 1,"ΔFGSG_10089:FGSG_10089 C to S Oex, ΔFGSG_10089:FGSG_10089C to F Oex",,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,flower,GPI-anchored cell wall protein,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30113774,PubMed,10.1111/mpp.12742,Mol Plant Pathol. 2018 Aug 16,Rajagopal.subramaniam@agr.gc.ca,Cys325 was necessary to cause disease and contribute to overall virulence function of the FGSG_10089 protein.,U Fernando 2018,2018,5 genes,Fernando-2018-Redox signalling from NADPH oxid,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11926,PHI:8366,UniProt,I1RWQ7,GenBank,XP_011319991,,,PH-1; NRRL 31084,FGSG_08737,chromosome 2,,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,flower,"woronin body protein, a glucokinase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30113774,PubMed,10.1111/mpp.12742,Mol Plant Pathol. 2018 Aug 16,Rajagopal.subramaniam@agr.gc.ca,No perithecia were detected in either NoxA/B double mutant strains or the ΔFGSG_08737 deletion strain compared to the wildtype (wt) strains.,U Fernando 2018,2018,5 genes,Fernando-2018-Redox signalling from NADPH oxid,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11927,PHI:8367,,no data found,,,,,,NoxA,,,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,flower,NADPH oxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30113774,PubMed,10.1111/mpp.12742,Mol Plant Pathol. 2018 Aug 16,Rajagopal.subramaniam@agr.gc.ca,No perithecia were detected in either NoxA/B double mutant strains or the ΔFGSG_08737 deletion strain compared to the wildtype (wt) strains.,U Fernando 2018,2018,5 genes,Fernando-2018-Redox signalling from NADPH oxid,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11928,PHI:8368,,no data found,,,,,,NoxB,,,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,flower,NADPH oxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30113774,PubMed,10.1111/mpp.12742,Mol Plant Pathol. 2018 Aug 16,Rajagopal.subramaniam@agr.gc.ca,No perithecia were detected in either NoxA/B double mutant strains or the ΔFGSG_08737 deletion strain compared to the wildtype (wt) strains.,U Fernando 2018,2018,5 genes,Fernando-2018-Redox signalling from NADPH oxid,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11929,PHI:8369,UniProt,V6RPS5,GenBank,CEF85274,,,PH-1,FGSG_09834,chromosome 4,,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,flower,pyruvate decarboxylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30113774,PubMed,10.1111/mpp.12742,Mol Plant Pathol. 2018 Aug 16,Rajagopal.subramaniam@agr.gc.ca,The ΔFGSG_09834 F. graminearum strain had no defects in virulence.,U Fernando 2018,2018,5 genes,Fernando-2018-Redox signalling from NADPH oxid,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11930,PHI:8370,UniProt,Q9I4E6,GenBank,AE004549_8,,,PAO1,ttcA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,tRNA-thiolating enzyme,,,,reduced virulence,,,,,,,,,,no,"H2O2; sodium hypochlorite (NaOCl); cumene hydroperoxide (CHP); paraquat (PQ); N-ethylmaleimide (NEM); 2,2'-dipyridyl (DIPY)","H2O2: CHEBI:16240; sodium hypochlorite (NaOCl): CHEBI:32146; cumene hydroperoxide (CHP): CHEBI:78673; paraquat (PQ): CHEBI:34905; N-ethylmaleimide (NEM): CHEBI:44485; 2,2'-dipyridyl (DIPY): CHEBI:30351",,,,,gene deletion: partial; gene complementation,,,YVS,30089777,PubMed,10.1038/s41598-018-30368-y,Sci Rep. 2018 Aug 8;8(1):11882,adisak.rom@mahidol.ac.th,Site-directed mutagenesis analysis revealed that the conserved cysteine motifs involved in [Fe-S] cluster ligation were required for TtcA function.,A Romsang 2018,2018,1 gene,Romsang-2018-Pseudomonas aeruginosa ttcA encod,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11931,PHI:8370,UniProt,Q9I4E6,GenBank,AE004549_8,,,PAO1,ttcA,,"C115S, C118S, C203S or C206S",,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,tRNA-thiolating enzyme,,,,reduced virulence,,,,,,,,,,no,"H2O2; sodium hypochlorite (NaOCl); cumene hydroperoxide (CHP); paraquat (PQ); N-ethylmaleimide (NEM); 2,2'-dipyridyl (DIPY)","H2O2: CHEBI:16240; sodium hypochlorite (NaOCl): CHEBI:32146; cumene hydroperoxide (CHP): CHEBI:78673; paraquat (PQ): CHEBI:34905; N-ethylmaleimide (NEM): CHEBI:44485; 2,2'-dipyridyl (DIPY): CHEBI:30351",,,,,gene mutation; gene complementation,,,YVS,30089777,PubMed,10.1038/s41598-018-30368-y,Sci Rep. 2018 Aug 8;8(1):11882,adisak.rom@mahidol.ac.th,Site-directed mutagenesis analysis revealed that the conserved cysteine motifs involved in [Fe-S] cluster ligation were required for TtcA function.,A Romsang 2018,2018,1 gene,Romsang-2018-Pseudomonas aeruginosa ttcA encod,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11932,PHI:8370,UniProt,Q9I4E6,GenBank,AE004549_8,,,PAO1,ttcA,,C38 or C184,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,tRNA-thiolating enzyme,,,,unaffected pathogenicity,,,,,,,,,,no,"H2O2; sodium hypochlorite (NaOCl); cumene hydroperoxide (CHP); paraquat (PQ); N-ethylmaleimide (NEM); 2,2'-dipyridyl (DIPY)","H2O2: CHEBI:16240; sodium hypochlorite (NaOCl): CHEBI:32146; cumene hydroperoxide (CHP): CHEBI:78673; paraquat (PQ): CHEBI:34905; N-ethylmaleimide (NEM): CHEBI:44485; 2,2'-dipyridyl (DIPY): CHEBI:30351",,,,,gene mutation; gene complementation,,,YVS,30089777,PubMed,10.1038/s41598-018-30368-y,Sci Rep. 2018 Aug 8;8(1):11882,adisak.rom@mahidol.ac.th,Site-directed mutagenesis analysis revealed that the conserved cysteine motifs involved in [Fe-S] cluster ligation were required for TtcA function.,A Romsang 2018,2018,1 gene,Romsang-2018-Pseudomonas aeruginosa ttcA encod,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11933,PHI:8371,UniProt,P41783,GenBank,AAL21754,,,LT2,prgH,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA420,salmonellosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,cell invasion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30204776,PubMed,10.1371/journal.pone.0203698,PLoS One. 2018 Sep 11;13(9):e0203698,mkpeed@ncsu.edu,STm mutants lacking the type-3 secretion system-1 induced less neutrophil ROS than the virulent WT.,T L Westerman 2018,2018,4 genes,Westerman-2018-The Salmonella type-3 secretion,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11934,PHI:8372,UniProt,P06179,GenBank,AAL20871,,,LT2,fliC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA420,salmonellosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,flagellar biosynthesis; flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30204776,PubMed,10.1371/journal.pone.0203698,PLoS One. 2018 Sep 11;13(9):e0203698,mkpeed@ncsu.edu,STm mutants lacking the type-3 secretion system-1 induced less neutrophil ROS than the virulent WT.,T L Westerman 2018,2018,4 genes,Westerman-2018-The Salmonella type-3 secretion,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11935,PHI:8373,UniProt,P52616,GenBank,AAL21657,,,LT2,fljB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA420,salmonellosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,filament structural protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30204776,PubMed,10.1371/journal.pone.0203698,PLoS One. 2018 Sep 11;13(9):e0203698,mkpeed@ncsu.edu,STm mutants lacking the type-3 secretion system-1 induced less neutrophil ROS than the virulent WT.,T L Westerman 2018,2018,4 genes,Westerman-2018-The Salmonella type-3 secretion,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11936,PHI:8374,UniProt,P55891,GenBank,AAL20839,,,LT2,motA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA420,salmonellosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,motility protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30204776,PubMed,10.1371/journal.pone.0203698,PLoS One. 2018 Sep 11;13(9):e0203698,mkpeed@ncsu.edu,STm mutants lacking the type-3 secretion system-1 induced less neutrophil ROS than the virulent WT.,T L Westerman 2018,2018,4 genes,Westerman-2018-The Salmonella type-3 secretion,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11937,PHI:8375,,no data found,GenBank,EYB27371,,,CS3005,FgABCC9 (FG05_07325),,,,,,,5518,Fusarium graminearum,,DAOM 180378,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,spikelet,ABC-C transporter,,,,reduced virulence,,,,,,,,reduced,,no,tebuconazole,tebuconazole: CHEBI:81781,,,,,gene deletion: full; gene complementation,,,YVS,30103374,PubMed,10.3390/ijms19082351,Int J Mol Sci. 2018 Aug 10;19(8). pii: E2351,ymwei@sicau.edu.cn,"Deletion of FgABCC9 resulted in decreased mycelial growth, increased sensitivity to SA and tebuconazole, reduced accumulation of deoxynivalenol (DON), and less pathogenicity towards wheat.",P F Qi 2018,2018,1 gene,Qi-2018-Fusarium graminearum ATP-Binding Casse,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11938,PHI:8376,UniProt,Q6NIN5,GenBank,CAE49255,,,NCTC13129,DIP0733,,,,,,,1717,Corynebacterium diphtheriae,698965,CDC-E8392,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,putative membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30180805,PubMed,10.1186/s12866-018-1247-z,BMC Microbiol. 2018 Sep 4;18(1):106,camila.a.azevedo@fau.de,"Infections of epithelial cells and transepithelial resistance assays revealed that bacteria expressing the truncated form of C. diphtheriae DIP0733 and C. glutamicum DIP0733 homolog are less virulent, while the fusion of the coiled-coil sequence to the DIP0733 homolog from C. glutamicum resulted in increased pathogenicity.",D Weerasekera 2018,2018,1 gene,Weerasekera-2018-The C-terminal coiled-coil do,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11939,PHI:8376,UniProt,Q6NIN5,GenBank,CAE49255,,,NCTC13129,DIP0733,,,,,,,1717,Corynebacterium diphtheriae,698965,CDC-E8392,diphtheria,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30180805,PubMed,10.1186/s12866-018-1247-z,BMC Microbiol. 2018 Sep 4;18(1):106,camila.a.azevedo@fau.de,"Infections of epithelial cells and transepithelial resistance assays revealed that bacteria expressing the truncated form of C. diphtheriae DIP0733 and C. glutamicum DIP0733 homolog are less virulent, while the fusion of the coiled-coil sequence to the DIP0733 homolog from C. glutamicum resulted in increased pathogenicity.",D Weerasekera 2018,2018,1 gene,Weerasekera-2018-The C-terminal coiled-coil do,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11940,PHI:8377,UniProt,A0A194VVU3,GenBank,KUI68351,,,03-8,VmPOD1,chromosome 4,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,catalase peroxidase,,,,unaffected pathogenicity,,,,,,reduced,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29959044,PubMed,10.1016/j.fgb.2018.08.003,Fungal Genet Biol. 2018 Oct;119:20-28,huanglili@nwsuaf.edu.cn,VmPODs were essential for conidiation and H2O2 stress resistance.,H Feng 2018,2018,3 genes,Feng-2018-Secreted peroxidases VmPODs play cri,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11941,PHI:8378,UniProt,A0A0M4AQD6,GenBank,KUI72246,,,03-8,VmPOD2,chromosome 8,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,chloroperoxidase,,,,unaffected pathogenicity,,,,,,reduced,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29959044,PubMed,10.1016/j.fgb.2018.08.003,Fungal Genet Biol. 2018 Oct;119:20-28,huanglili@nwsuaf.edu.cn,VmPODs were essential for conidiation and H2O2 stress resistance.,H Feng 2018,2018,3 genes,Feng-2018-Secreted peroxidases VmPODs play cri,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11942,PHI:8379,UniProt,A0A194VJP7,GenBank,KUI64100,,,03-8,VmPOD3,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,plant peroxidase-like peroxidase,,,,reduced virulence,,,,,,reduced,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,29959044,PubMed,10.1016/j.fgb.2018.08.003,Fungal Genet Biol. 2018 Oct;119:20-28,huanglili@nwsuaf.edu.cn,VmPODs were essential for conidiation and H2O2 stress resistance.,H Feng 2018,2018,3 genes,Feng-2018-Secreted peroxidases VmPODs play cri,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11943,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Rollag,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11944,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Rollag,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11945,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Velva,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11946,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Velva,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11947,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Jenna,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11948,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Jenna,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11949,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. RB07,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11950,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. RB07,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11951,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Brennan,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11952,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Brennan,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11953,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Glenn,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11954,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Glenn,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11955,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Briggs,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11956,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Briggs,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11957,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Chinese Spring,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11958,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Chinese Spring,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11959,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Prosper,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11960,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Prosper,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11961,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Vantage,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11962,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Vantage,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11963,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Wesley,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11964,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Wesley,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11965,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Howard,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11966,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Howard,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11967,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Kelby,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11968,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Kelby,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11969,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Select,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11970,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Select,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11971,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. SY Soren,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11972,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. SY Soren,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11973,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. SY Tyra,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11974,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. SY Tyra,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11975,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Mott,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11976,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Mott,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11977,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Steele-ND,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11978,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Steele-ND,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11979,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Harry,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11980,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Harry,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11981,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Barlow,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11982,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Barlow,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11983,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Rollag,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11984,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Rollag,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11985,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Velva,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11986,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Velva,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11987,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Jenna,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11988,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Jenna,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11989,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. RB07,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11990,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. RB07,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11991,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Brennan,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11992,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Brennan,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11993,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Glenn,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11994,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Glenn,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11995,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Briggs,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11996,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Briggs,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11997,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Chinese Spring,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11998,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Chinese Spring,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 11999,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Prosper,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12000,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Prosper,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12001,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Vantage,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12002,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Vantage,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12003,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Wesley,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12004,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Wesley,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12005,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Howard,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12006,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Howard,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12007,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Kelby,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12008,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Kelby,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12009,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Select,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12010,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Select,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12011,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. SY Soren,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12012,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. SY Soren,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12013,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. SY Tyra,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12014,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. SY Tyra,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12015,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Mott,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12016,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Mott,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12017,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Steele-ND,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12018,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Steele-ND,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12019,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Harry,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12020,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Harry,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12021,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Barlow,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12022,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Barlow,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12023,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Salamouni,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12024,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Salamouni,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12025,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Glenlea,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12026,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Glenlea,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12027,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. 6B365,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12028,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. 6B365,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12029,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. 6B662,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12030,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. 6B662,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12031,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. ND495,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12032,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. ND495,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12033,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Alkabo,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12034,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Alkabo,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12035,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Lebsock,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12036,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Lebsock,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12037,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Grenora,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12038,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Grenora,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12039,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Carpio,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12040,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Carpio,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12041,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Tioga,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12042,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Tioga,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12043,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Ben,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12044,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Ben,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12045,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Dilse,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12046,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Dilse,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12047,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Divide,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12048,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Divide,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12049,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Langdon,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12050,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Langdon,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12051,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Rusty,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12052,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Rusty,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12053,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Mountrail,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12054,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Mountrail,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12055,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Pierce,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12056,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B16,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Pierce,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12057,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Alkabo,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12058,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Alkabo,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12059,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Lebsock,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12060,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Lebsock,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12061,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Grenora,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12062,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Grenora,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12063,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Carpio,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12064,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Carpio,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12065,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Tioga,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12066,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Tioga,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12067,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Ben,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12068,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Ben,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12069,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Dilse,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12070,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Dilse,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12071,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Divide,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12072,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Divide,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12073,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Langdon,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12074,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Langdon,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12075,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Rusty,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12076,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Rusty,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12077,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Mountrail,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12078,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Mountrail,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12079,PHI:8380,UniProt,P78737,GenBank,ADY05382,,,PTR-01,ToxA (AAB61464),,,,,,PHI:8381,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Pierce,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12080,PHI:8381,UniProt,Q9C173,GenBank,AF483831_1,,,Alg 3-24,ToxB (AAO73337),,,,,,PHI:8380,45151,Pyrenophora tritici-repentis,,race 4 strain B17,tan spot (wheat),monocots,4571,Triticum turgidum (related: rivet wheat),subsp. durum cv. Pierce,,,leaf,necrotrophic effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,YVS,30213041,PubMed,10.3390/pathogens7030074,Pathogens. 2018 Sep 12;7(3). pii: E74,zhh.liu@ndsu.edu,It was demonstrated that the fungal pathogen produced additional necrotrophic effectors or other types of virulence factors besides the three known ones.,J Guo 2018,2018,2 genes,Guo-2018-Characterizing Virulence of the Pyren,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12081,PHI:8382,UniProt,A0A068C8U8,GenBank,AID16239,,,Af293,Rho1,chromosome 6,,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,small GTPase,,,,reduced virulence,,,,,,,,reduced,,no,calcofluor white; Congo red; H2O2; SDS; farnesol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; farnesol: CHEBI:28600,,,,,gene deletion: full,,,YVS,30205199,PubMed,10.1016/j.fgb.2018.09.003,Fungal Genet Biol. 2018 Sep 8;120:30-41,hanlicdc@163.com,Decrease of AfRho1 expression inhibited conidial internalization into lung epithelial cells and inflammatory factor release.,X Zhang 2018,2018,1 gene,Zhang-2018-Role of the small GTPase Rho1 in ce,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12082,PHI:8382,UniProt,A0A068C8U8,GenBank,AID16239,,,Af293,Rho1,chromosome 6,,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,small GTPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white; Congo red; H2O2; SDS; farnesol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; farnesol: CHEBI:28600,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30205199,PubMed,10.1016/j.fgb.2018.09.003,Fungal Genet Biol. 2018 Sep 8;120:30-41,hanlicdc@163.com,Decrease of AfRho1 expression inhibited conidial internalization into lung epithelial cells and inflammatory factor release.,X Zhang 2018,2018,1 gene,Zhang-2018-Role of the small GTPase Rho1 in ce,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12083,PHI:8382,UniProt,A0A068C8U8,GenBank,AID16239,,,Af293,Rho1,chromosome 6,,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,small GTPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white; Congo red; H2O2; SDS; farnesol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; farnesol: CHEBI:28600,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30205199,PubMed,10.1016/j.fgb.2018.09.003,Fungal Genet Biol. 2018 Sep 8;120:30-41,hanlicdc@163.com,Decrease of AfRho1 expression inhibited conidial internalization into lung epithelial cells and inflammatory factor release.,X Zhang 2018,2018,1 gene,Zhang-2018-Role of the small GTPase Rho1 in ce,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12084,PHI:8383,UniProt,Q7MU78,GenBank,AAQ66693,,,W83,pckA (PG1676),,,,,,,837,Porphyromonas gingivalis,242619,W83,periodontitis,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,gingipain production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30126013,PubMed,10.1111/eos.12565,Eur J Oral Sci. 2018 Aug 20,yfw1110@163.com,Inactivation of the pckA gene did not affect bacterial growth and lipopolysaccharide formation but led to a reduction in hemagglutination activity.,L Wu 2018,2018,1 gene,Wu-2018-pckA-deficient Porphyromonas gingivali,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12085,PHI:8384,UniProt,D0MS08,GenBank,EEY58277,,,T30-4,PLD-like-1 (PITG_00921),,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,phospholipase D (PLD) like protein,,,,reduced virulence,,,,,,,,,,no,CaCl2; Ca(NO3)2; MnSO4; MgCl2; ZnCl2,"CaCl2: CHEBI:3312, 2; Ca(NO3): CHEBI:64205; MnSO4 CAS no.: CAS:7785-87-7; MgCl2: CHEBI:6636; ZnCl2: CHEBI:49976",,,,,altered gene expression / gene regulation; other evidence: transgenic plants,,,YVS,30171659,PubMed,10.1111/mpp.12746,Mol Plant Pathol. 2018 Sep 1,francine.govers@wur.nl,"Deletion of the signal peptide and mutations in the catalytic HKD motifs strongly reduced the cell death responses and abolished virulence promotion, demonstrating that the enzymatic activity of the PLDs was the major determinant.",H J G Meijer 2018,2018,3 genes,Meijer-2018-Phytophthora infestans small phosp,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12086,PHI:8385,UniProt,D0NX76,GenBank,EEY67671,,,T30-4,sPLD-like-1 (PITG_18185),,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,phospholipase D (PLD) like protein,,,,reduced virulence,,,,,,,,,,no,CaCl2; Ca(NO3)2; MnSO4; MgCl2; ZnCl2,"CaCl2: CHEBI:3312, 2; Ca(NO3): CHEBI:64205; MnSO4 CAS no.: CAS:7785-87-7; MgCl2: CHEBI:6636; ZnCl2: CHEBI:49976",,,,,altered gene expression / gene regulation; other evidence: transgenic plants,,,YVS,30171659,PubMed,10.1111/mpp.12746,Mol Plant Pathol. 2018 Sep 1,francine.govers@wur.nl,"Deletion of the signal peptide and mutations in the catalytic HKD motifs strongly reduced the cell death responses and abolished virulence promotion, demonstrating that the enzymatic activity of the PLDs was the major determinant.",H J G Meijer 2018,2018,3 genes,Meijer-2018-Phytophthora infestans small phosp,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12087,PHI:8386,UniProt,D0NL74,GenBank,EEY60392,,,T30-4,sPLD-like-12 (PITG_12806),,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,phospholipase D (PLD) like protein,,,,reduced virulence,,,,,,,,,,no,CaCl2; Ca(NO3)2; MnSO4; MgCl2; ZnCl2,"CaCl2: CHEBI:3312, 2; Ca(NO3): CHEBI:64205; MnSO4 CAS no.: CAS:7785-87-7; MgCl2: CHEBI:6636; ZnCl2: CHEBI:49976",,,,,altered gene expression / gene regulation; other evidence: transgenic plants,,,YVS,30171659,PubMed,10.1111/mpp.12746,Mol Plant Pathol. 2018 Sep 1,francine.govers@wur.nl,"Deletion of the signal peptide and mutations in the catalytic HKD motifs strongly reduced the cell death responses and abolished virulence promotion, demonstrating that the enzymatic activity of the PLDs was the major determinant.",H J G Meijer 2018,2018,3 genes,Meijer-2018-Phytophthora infestans small phosp,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12088,PHI:8384,UniProt,D0MS08,GenBank,EEY58277,,,T30-4,PLD-like-1 (PITG_00921),,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,phospholipase D (PLD) like protein,,,,reduced virulence,,,,,,,,,,no,CaCl2; Ca(NO3)2; MnSO4; MgCl2; ZnCl2,"CaCl2: CHEBI:3312, 2; Ca(NO3): CHEBI:64205; MnSO4 CAS no.: CAS:7785-87-7; MgCl2: CHEBI:6636; ZnCl2: CHEBI:49976",,,,,gene mutation,,,YVS,30171659,PubMed,10.1111/mpp.12746,Mol Plant Pathol. 2018 Sep 1,francine.govers@wur.nl,"Deletion of the signal peptide and mutations in the catalytic HKD motifs strongly reduced the cell death responses and abolished virulence promotion, demonstrating that the enzymatic activity of the PLDs was the major determinant.",H J G Meijer 2018,2018,3 genes,Meijer-2018-Phytophthora infestans small phosp,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12089,PHI:8385,UniProt,D0NX76,GenBank,EEY67671,,,T30-4,sPLD-like-1 (PITG_18185),,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,phospholipase D (PLD) like protein,,,,reduced virulence,,,,,,,,,,no,CaCl2; Ca(NO3)2; MnSO4; MgCl2; ZnCl2,"CaCl2: CHEBI:3312, 2; Ca(NO3): CHEBI:64205; MnSO4 CAS no.: CAS:7785-87-7; MgCl2: CHEBI:6636; ZnCl2: CHEBI:49976",,,,,gene mutation,,,YVS,30171659,PubMed,10.1111/mpp.12746,Mol Plant Pathol. 2018 Sep 1,francine.govers@wur.nl,"Deletion of the signal peptide and mutations in the catalytic HKD motifs strongly reduced the cell death responses and abolished virulence promotion, demonstrating that the enzymatic activity of the PLDs was the major determinant.",H J G Meijer 2018,2018,3 genes,Meijer-2018-Phytophthora infestans small phosp,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12090,PHI:8386,UniProt,D0NL74,GenBank,EEY60392,,,T30-4,sPLD-like-12 (PITG_12806),,,,,,,4787,Phytophthora infestans,,NL-88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,phospholipase D (PLD) like protein,,,,reduced virulence,,,,,,,,,,no,CaCl2; Ca(NO3)2; MnSO4; MgCl2; ZnCl2,"CaCl2: CHEBI:3312, 2; Ca(NO3): CHEBI:64205; MnSO4 CAS no.: CAS:7785-87-7; MgCl2: CHEBI:6636; ZnCl2: CHEBI:49976",,,,,gene mutation,,,YVS,30171659,PubMed,10.1111/mpp.12746,Mol Plant Pathol. 2018 Sep 1,francine.govers@wur.nl,"Deletion of the signal peptide and mutations in the catalytic HKD motifs strongly reduced the cell death responses and abolished virulence promotion, demonstrating that the enzymatic activity of the PLDs was the major determinant.",H J G Meijer 2018,2018,3 genes,Meijer-2018-Phytophthora infestans small phosp,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12091,PHI:8387,,no data found,,,,,,rel,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,infective endocarditis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ear; blood,molecular alarmone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30091695,PubMed,10.1099/mic.0.000703,Microbiology. 2018 Aug 9,kristi.frank@usuhs.edu,"Since neither the Δrel nor the ΔrelΔrelQ strain activated the stringent response, but only the Δrel strain was attenuated in infective endocarditis model, the results suggested that activation of the stringent response was not required for E. faecalis IE virulence.",C Colomer-Winter 2018,2018,2 genes,Colomer-Winter-2018-Basal levels of (p)ppGpp d,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12092,PHI:8388,,no data found,,,,,,relQ,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,infective endocarditis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ear; blood,molecular alarmone,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30091695,PubMed,10.1099/mic.0.000703,Microbiology. 2018 Aug 9,kristi.frank@usuhs.edu,"Since neither the Δrel nor the ΔrelΔrelQ strain activated the stringent response, but only the Δrel strain was attenuated in infective endocarditis model, the results suggested that activation of the stringent response was not required for E. faecalis IE virulence.",C Colomer-Winter 2018,2018,2 genes,Colomer-Winter-2018-Basal levels of (p)ppGpp d,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12093,PHI:8387,,no data found,,,,,,rel,,,,,,PHI:8388,1351,Enterococcus faecalis,474186,OG1RF,infective endocarditis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ear; blood,molecular alarmone,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30091695,PubMed,10.1099/mic.0.000703,Microbiology. 2018 Aug 9,kristi.frank@usuhs.edu,"Since neither the Δrel nor the ΔrelΔrelQ strain activated the stringent response, but only the Δrel strain was attenuated in infective endocarditis model, the results suggested that activation of the stringent response was not required for E. faecalis IE virulence.",C Colomer-Winter 2018,2018,2 genes,Colomer-Winter-2018-Basal levels of (p)ppGpp d,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12094,PHI:8388,,no data found,,,,,,relQ,,,,,,PHI:8387,1351,Enterococcus faecalis,474186,OG1RF,infective endocarditis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ear; blood,molecular alarmone,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30091695,PubMed,10.1099/mic.0.000703,Microbiology. 2018 Aug 9,kristi.frank@usuhs.edu,"Since neither the Δrel nor the ΔrelΔrelQ strain activated the stringent response, but only the Δrel strain was attenuated in infective endocarditis model, the results suggested that activation of the stringent response was not required for E. faecalis IE virulence.",C Colomer-Winter 2018,2018,2 genes,Colomer-Winter-2018-Basal levels of (p)ppGpp d,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12095,PHI:8389,UniProt,A8FMC8,GenBank,ABV52615,,,81116; NCTC 11828,FliW,,,,,,,197,Campylobacter jejuni,354242,81-176,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,cecum,flagellar chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30113298,PubMed,10.1099/mic.0.000704,Microbiology. 2018 Aug 16,stthomps@augusta.edu,The defects in flagellar production and motility of ΔfliW mutant were reflected in a chick colonization defect.,J Li 2018,2018,1 gene,Li-2018-FliW controls growth-phase expression,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12096,PHI:8390,UniProt,Q00909,GenBank,AAB72033,,,w-8,tri5,,,,,,,5518,Fusarium graminearum,,Fg 8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spike; rachis node,trichodiene synthase,,,DON biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; chemical complementation,,,YVS,30084118,PubMed,10.1111/nph.15377,New Phytol. 2018 Aug 7,joerg.bormann@uni-bremen.de,"Wild-type infection resulted in an oxidative burst and the induction of plant programmedcell death, while spread of the DON-deficient Δtri5 mutant was blocked in a jasmonate (JA)-related defense reaction in concert with other factors.",J Bonnighausen 2018,2018,1 gene,Bonnighausen-2018-Metabolic profiling of wheat,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12097,PHI:8391,UniProt,S3MCE5,GenBank,EPF64158,,,SM,topB3,,,,,,,317,Pseudomonas syringae,319,pv. phaseolicola strain 1302A,blight (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Tendergreen,,,leaf,type IA topoisomerase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30152900,PubMed,10.1111/mmi.14111,Mol Microbiol. 2018 Aug 28,Dawn.Arnold@uwe.ac.uk,An insertional mutant of topB3 displayed an increase in avrPphB expression and an increase in PPHGI-1 excision as well as reduced population growth in resistant and susceptible cultivars of bean.,H C Neale 2018,2018,1 gene,Neale-2018-Supercoiling of an excised genomic,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12098,PHI:8391,UniProt,S3MCE5,GenBank,EPF64158,,,SM,topB3,,,,,,,317,Pseudomonas syringae,319,pv. phaseolicola strain 1302A,blight (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Canadian Wonder,,,leaf,type IA topoisomerase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30152900,PubMed,10.1111/mmi.14111,Mol Microbiol. 2018 Aug 28,Dawn.Arnold@uwe.ac.uk,An insertional mutant of topB3 displayed an increase in avrPphB expression and an increase in PPHGI-1 excision as well as reduced population growth in resistant and susceptible cultivars of bean.,H C Neale 2018,2018,1 gene,Neale-2018-Supercoiling of an excised genomic,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12099,PHI:8392,UniProt,A0A0K0GFX3,GenBank,ACD56999,,,PXO99A,edpX1,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30217836,PubMed,10.1128/AEM.01717-18,Appl Environ Microbiol. 2018 Sep 14. pii: AEM.01717-18,hechenyang@caas.cn,ΔEdpX1 was defective in secreting exopolysaccharide (EPS) and forming biofilm.,D Xue 2018,2018,1 gene,Xue-2018-Phosphodiesterase EdpX1 promotes viru,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12100,PHI:8392,UniProt,A0A0K0GFX3,GenBank,ACD56999,,,PXO99A,edpX1,,E153A,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30217836,PubMed,10.1128/AEM.01717-18,Appl Environ Microbiol. 2018 Sep 14. pii: AEM.01717-18,hechenyang@caas.cn,ΔEdpX1 was defective in secreting exopolysaccharide (EPS) and forming biofilm.,D Xue 2018,2018,1 gene,Xue-2018-Phosphodiesterase EdpX1 promotes viru,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12101,PHI:8393,UniProt,X5DSM8,GenBank,AVG63806,,,FDAARGOS_6,SSL13,,,,,,,1280,Staphylococcus aureus,426430,subsp. aureus strain Newman,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,neutrophil,neutrophil chemoattractant,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,30098280,PubMed,10.1111/cmi.12941,Cell Microbiol. 2018 Aug 11:e12941,p.j.a.haas@umcutrecht.nl,"Human neutrophil stimulation by SSL13 was inhibited by formyl peptide receptor-like 1 inhibitory protein (FLIPr), not chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS).",Y Zhao 2018,2018,1 gene,Zhao-2018-Staphylococcal superantigen-like pro,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12102,PHI:8393,UniProt,X5DSM8,GenBank,AVG63806,,,FDAARGOS_6,SSL13,,,,,,,1280,Staphylococcus aureus,426430,subsp. aureus strain Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,neutrophil,neutrophil chemoattractant,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,30098280,PubMed,10.1111/cmi.12941,Cell Microbiol. 2018 Aug 11:e12941,p.j.a.haas@umcutrecht.nl,SSL13 was not able to efficiently activate mouse neutrophils.,Y Zhao 2018,2018,1 gene,Zhao-2018-Staphylococcal superantigen-like pro,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12103,PHI:8394,UniProt,Q0P897,GenBank,CAL35627,,,NCTC 11168,cas9,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative CRISPR-associated protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30177957,PubMed,10.3389/fcimb.2018.00285,Front Cell Infect Microbiol. 2018 Aug 20;8:285,haohaihong@mail.hzau.edu.cn,"ΔCas9 mutant was compromised in terms of biofilm formation, motility, adhesion, invasion, intracellular survivability and cytotoxin production compared to wild type strain.",M A B Shabbir 2018,2018,1 gene,Shabbir-2018-The Involvement of the Cas9 Gene,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12104,PHI:8395,UniProt,Q6FIU2,,,,,,Cghog1,,,,,,,5478,Candida glabrata,,BG14,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,MAP kinase,,,high osmolarity glycerol response (HOG) MAP kinase pathway,reduced virulence,,,,,,,,,,no,NaCl; H2O2; glycerol; fluconazole; lactic acid; sorbic acid; phenyl acetic acid; bathophenanthrolinedisulfonic acid,"NaCl: CHEBI:26710; H2O2: CHEBI:16240; glycerol: CHEBI:17754; fluconazole: CHEBI:46081, CAS:86386-73-4; lactic acid: CHEBI:28358; sorbic acid: CHEBI:35962; phenyl acetic acid: CHEBI:30745; bathophenanthrolinedisulfonic acid: CHEBI:78159",,,,,gene mutation; gene complementation,,,YVS,30112857,PubMed,10.1111/cmi.12943,Cell Microbiol. 2018 Aug 15:e12943,christoph.schueller@boku.ac.at,CgHog1 was required for survival in macrophages but was dispensable for systemic infection.,R Beyer 2018,2018,1 gene,Beyer-2018-Competition of Candida glabrata aga,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12105,PHI:8395,UniProt,Q6FIU2,,,,,,Cghog1,,,,,,,5478,Candida glabrata,,BG14,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,brain; kidney; spleen; liver,MAP kinase,,,high osmolarity glycerol response (HOG) MAP kinase pathway,unaffected pathogenicity,,,,,,,,,,no,NaCl; H2O2; glycerol; fluconazole; lactic acid; sorbic acid; phenyl acetic acid; bathophenanthrolinedisulfonic acid,"NaCl: CHEBI:26710; H2O2: CHEBI:16240; glycerol: CHEBI:17754; fluconazole: CHEBI:46081, CAS:86386-73-4; lactic acid: CHEBI:28358; sorbic acid: CHEBI:35962; phenyl acetic acid: CHEBI:30745; bathophenanthrolinedisulfonic acid: CHEBI:78159",,,,,gene mutation; gene complementation,,,YVS,30112857,PubMed,10.1111/cmi.12943,Cell Microbiol. 2018 Aug 15:e12943,christoph.schueller@boku.ac.at,CgHog1 was required for survival in macrophages but was dispensable for systemic infection.,R Beyer 2018,2018,1 gene,Beyer-2018-Competition of Candida glabrata aga,BATCH_086A,2018-09-01,MC,,,,,,,,,,,,,
,,Record 12106,PHI:8396,,no data found,,,,,,FgSec2A,,,,FgRab8,UniProt: no data found; GenBank: no data found,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,guanine nucleotide exchange factor,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,reduced,wild type,reduced; aberrant,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30105886,PubMed,10.1111/1462-2920.14373,Environ Microbiol. 2018 Sep;20(9):3378-3392,jiezhou@fafu.edu.cn,FgSEC2A was dispensable during conidia morphogenesis and sexual reproduction in F.graminearum.,H Zheng 2018,2018,3 genes,"Zheng-2018-FgSec2A, a guanine nucleotide excha",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12107,PHI:8396,,no data found,,,,,,FgSec2A,,,,FgRab8,UniProt: no data found; GenBank: no data found,PHI:8397,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,guanine nucleotide exchange factor,,,deoxynivalenol biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30105886,PubMed,10.1111/1462-2920.14373,Environ Microbiol. 2018 Sep;20(9):3378-3392,jiezhou@fafu.edu.cn,FgSEC2A was dispensable during conidia morphogenesis and sexual reproduction in F.graminearum.,H Zheng 2018,2018,3 genes,"Zheng-2018-FgSec2A, a guanine nucleotide excha",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12108,PHI:8397,,no data found,,,,,,FgRab8,,Constitutionally active - FgRab8CA(Q69L),,FgSec2A,UniProt: no data found; GenBank: no data found,PHI:8396,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,member of Rab GTPase family,,,deoxynivalenol biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30105886,PubMed,10.1111/1462-2920.14373,Environ Microbiol. 2018 Sep;20(9):3378-3392,jiezhou@fafu.edu.cn,FgSEC2A was dispensable during conidia morphogenesis and sexual reproduction in F.graminearum.,H Zheng 2018,2018,3 genes,"Zheng-2018-FgSec2A, a guanine nucleotide excha",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12109,PHI:8396,,no data found,,,,,,FgSec2A,,,,FgRab8,UniProt: no data found; GenBank: no data found,PHI:8397,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,guanine nucleotide exchange factor,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30105886,PubMed,10.1111/1462-2920.14373,Environ Microbiol. 2018 Sep;20(9):3378-3392,jiezhou@fafu.edu.cn,FgSEC2A was dispensable during conidia morphogenesis and sexual reproduction in F.graminearum.,H Zheng 2018,2018,3 genes,"Zheng-2018-FgSec2A, a guanine nucleotide excha",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12110,PHI:8397,,no data found,,,,,,FgRab8,,Dominant negative - FgRab8DN(N123I),,FgSec2A,UniProt: no data found; GenBank: no data found,PHI:8396,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,member of Rab GTPase family,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30105886,PubMed,10.1111/1462-2920.14373,Environ Microbiol. 2018 Sep;20(9):3378-3392,jiezhou@fafu.edu.cn,FgSEC2A was dispensable during conidia morphogenesis and sexual reproduction in F.graminearum.,H Zheng 2018,2018,3 genes,"Zheng-2018-FgSec2A, a guanine nucleotide excha",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12111,PHI:8398,UniProt,I1S8E1,GenBank,XP_011327072,,,PH-1; NRRL 31084,FgSec2B (FGSG_13119),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,guanine nucleotide exchange factor,,,deoxynivalenol biosynthesis,unaffected pathogenicity,,,,,,wild type,wild type,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30105886,PubMed,10.1111/1462-2920.14373,Environ Microbiol. 2018 Sep;20(9):3378-3392,jiezhou@fafu.edu.cn,FgSEC2A was dispensable during conidia morphogenesis and sexual reproduction in F.graminearum.,H Zheng 2018,2018,3 genes,"Zheng-2018-FgSec2A, a guanine nucleotide excha",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12112,PHI:8396,,no data found,,,,,,FgSec2A,,,,FgRab8,UniProt: no data found; GenBank: no data found,PHI:8398,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,guanine nucleotide exchange factor,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,,wild type,reduced; aberrant,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30105886,PubMed,10.1111/1462-2920.14373,Environ Microbiol. 2018 Sep;20(9):3378-3392,jiezhou@fafu.edu.cn,FgSEC2A was dispensable during conidia morphogenesis and sexual reproduction in F.graminearum.,H Zheng 2018,2018,3 genes,"Zheng-2018-FgSec2A, a guanine nucleotide excha",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12113,PHI:8398,UniProt,I1S8E1,GenBank,XP_011327072,,,PH-1; NRRL 31084,FgSec2B (FGSG_13119),chromosome 4,,,,,PHI:8396,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,guanine nucleotide exchange factor,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,,wild type,reduced; aberrant,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30105886,PubMed,10.1111/1462-2920.14373,Environ Microbiol. 2018 Sep;20(9):3378-3392,jiezhou@fafu.edu.cn,FgSEC2A was dispensable during conidia morphogenesis and sexual reproduction in F.graminearum.,H Zheng 2018,2018,3 genes,"Zheng-2018-FgSec2A, a guanine nucleotide excha",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12114,PHI:8399,UniProt,Q92C58,GenBank,CAC99373,,,EGD-e,hfq,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; mesenteric lymph node; liver,regulator factor,,,carbon and nitrogen metabolic pathways,unaffected pathogenicity,,,,,,,,reduced,,no,ethanol; triton X-100,ethanol: CHEBI:16236; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,30172301,PubMed,10.1016/j.micres.2018.07.001,Microbiol Res. 2018 Oct;215:148-154,yylan@yzu.edu.cn,Hfq played a crucial role in biofilm formation and resistance to strongly acidic environments.,H Yao 2018,2018,1 gene,Yao-2018-An essential role for hfq involved in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12115,PHI:8399,UniProt,Q92C58,GenBank,CAC99373,,,EGD-e,hfq,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,regulator factor,,,carbon and nitrogen metabolic pathways,reduced virulence,,,,,,,,reduced,,no,ethanol; triton X-100,ethanol: CHEBI:16236; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,30172301,PubMed,10.1016/j.micres.2018.07.001,Microbiol Res. 2018 Oct;215:148-154,yylan@yzu.edu.cn,Hfq played a crucial role in biofilm formation and resistance to strongly acidic environments.,H Yao 2018,2018,1 gene,Yao-2018-An essential role for hfq involved in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12116,PHI:8399,UniProt,Q92C58,GenBank,CAC99373,,,EGD-e,hfq,,,,,,,1639,Listeria monocytogenes,,NTSN,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; mesenteric lymph node; spleen; liver,regulator factor,,,carbon and nitrogen metabolic pathways,reduced virulence,,,,,,,,reduced,,no,ethanol; triton X-100,ethanol: CHEBI:16236; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,30172301,PubMed,10.1016/j.micres.2018.07.001,Microbiol Res. 2018 Oct;215:148-154,yylan@yzu.edu.cn,Hfq played a crucial role in biofilm formation and resistance to strongly acidic environments.,H Yao 2018,2018,1 gene,Yao-2018-An essential role for hfq involved in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12117,PHI:8399,UniProt,Q92C58,GenBank,CAC99373,,,EGD-e,hfq,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line,,,Caco-2/BBe cell,regulator factor,,,carbon and nitrogen metabolic pathways,reduced virulence,,,,,,,,reduced,,no,ethanol; triton X-100,ethanol: CHEBI:16236; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,30172301,PubMed,10.1016/j.micres.2018.07.001,Microbiol Res. 2018 Oct;215:148-154,yylan@yzu.edu.cn,Hfq played a crucial role in biofilm formation and resistance to strongly acidic environments. colonic adenocarcinoma epithelial cell line,H Yao 2018,2018,1 gene,Yao-2018-An essential role for hfq involved in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12118,PHI:8399,UniProt,Q92C58,GenBank,CAC99373,,,EGD-e,hfq,,,,,,,1639,Listeria monocytogenes,,NTSN,listeriosis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line,,,Caco-2/BBe cell,regulator factor,,,carbon and nitrogen metabolic pathways,reduced virulence,,,,,,,,reduced,,no,ethanol; triton X-100,ethanol: CHEBI:16236; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,30172301,PubMed,10.1016/j.micres.2018.07.001,Microbiol Res. 2018 Oct;215:148-154,yylan@yzu.edu.cn,Hfq played a crucial role in biofilm formation and resistance to strongly acidic environments. colonic adenocarcinoma epithelial cell line,H Yao 2018,2018,1 gene,Yao-2018-An essential role for hfq involved in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12119,PHI:8399,UniProt,Q92C58,GenBank,CAC99373,,,EGD-e,hfq,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,regulator factor,,,carbon and nitrogen metabolic pathways,reduced virulence,,,,,,,,reduced,,no,ethanol; triton X-100,ethanol: CHEBI:16236; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,30172301,PubMed,10.1016/j.micres.2018.07.001,Microbiol Res. 2018 Oct;215:148-154,yylan@yzu.edu.cn,Hfq played a crucial role in biofilm formation and resistance to strongly acidic environments.,H Yao 2018,2018,1 gene,Yao-2018-An essential role for hfq involved in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12120,PHI:8399,UniProt,Q92C58,GenBank,CAC99373,,,EGD-e,hfq,,,,,,,1639,Listeria monocytogenes,,NTSN,listeriosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,regulator factor,,,carbon and nitrogen metabolic pathways,reduced virulence,,,,,,,,reduced,,no,ethanol; triton X-100,ethanol: CHEBI:16236; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,30172301,PubMed,10.1016/j.micres.2018.07.001,Microbiol Res. 2018 Oct;215:148-154,yylan@yzu.edu.cn,Hfq played a crucial role in biofilm formation and resistance to strongly acidic environments.,H Yao 2018,2018,1 gene,Yao-2018-An essential role for hfq involved in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12121,PHI:8400,UniProt,A7E774,GenBank,EDN96226,,,1980,Sssfh1 (SS1G_01151),,,,SsMSG5 (SS1G_06950),UniProt: A7ENQ1; GenBank: EDO04467,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3847,Glycine max (related: soybean),,,,leaf,transcription factor,,,,reduced virulence,,,,,,,,aberrant,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,30131794,PubMed,10.3389/fmicb.2018.01828,Front Microbiol. 2018 Aug 7;9:1828,panhongyu@jlu.edu.cn,"SsSFH1 was involved in growth, ROS accumulation and virulence in S. sclerotiorum.",L Liu 2018,2018,1 gene,"Liu-2018-Sssfh1, a Gene Encoding a Putative Co",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12122,PHI:8400,UniProt,A7E774,GenBank,EDN96226,,,1980,Sssfh1 (SS1G_01151),,,,SsMSG5 (SS1G_06950),UniProt: A7ENQ1; GenBank: EDO04467,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,transcription factor,,,,reduced virulence,,,,,,,,aberrant,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,30131794,PubMed,10.3389/fmicb.2018.01828,Front Microbiol. 2018 Aug 7;9:1828,panhongyu@jlu.edu.cn,"SsSFH1 was involved in growth, ROS accumulation and virulence in S. sclerotiorum.",L Liu 2018,2018,1 gene,"Liu-2018-Sssfh1, a Gene Encoding a Putative Co",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12123,PHI:8400,UniProt,A7E774,GenBank,EDN96226,,,1980,Sssfh1 (SS1G_01151),,,,SsMSG5 (SS1G_06950),UniProt: A7ENQ1; GenBank: EDO04467,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,transcription factor,,,,reduced virulence,,,,,,,,aberrant,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,30131794,PubMed,10.3389/fmicb.2018.01828,Front Microbiol. 2018 Aug 7;9:1828,panhongyu@jlu.edu.cn,"SsSFH1 was involved in growth, ROS accumulation and virulence in S. sclerotiorum.",L Liu 2018,2018,1 gene,"Liu-2018-Sssfh1, a Gene Encoding a Putative Co",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12124,PHI:8401,UniProt,Q2FX12,GenBank,ABD31145,,,NCTC 8325,ptpA,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,secreted tyrosine phosphatase,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene mutation; gene complementation,,,YVS,30131335,PubMed,10.1074/jbc.RA118.003555,J Biol Chem. 2018 Oct 5;293(40):15569-15580,virginie.molle@univ-montp2.fr,Deletion of ptpA in S. aureus affected intramacrophage survival and infectivity.,L Gannoun-Zaki 2018,2018,1 gene,"Gannoun-Zaki-2018-PtpA, a secreted tyrosine ph",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12125,PHI:8401,UniProt,Q2FX12,GenBank,ABD31145,,,NCTC 8325,ptpA,,,,,,,1280,Staphylococcus aureus,,SA564,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,secreted tyrosine phosphatase,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene mutation; gene complementation,,,YVS,30131335,PubMed,10.1074/jbc.RA118.003555,J Biol Chem. 2018 Oct 5;293(40):15569-15580,virginie.molle@univ-montp2.fr,Deletion of ptpA in S. aureus affected intramacrophage survival and infectivity.,L Gannoun-Zaki 2018,2018,1 gene,"Gannoun-Zaki-2018-PtpA, a secreted tyrosine ph",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12126,PHI:8401,UniProt,Q2FX12,GenBank,ABD31145,,,NCTC 8325,ptpA,,,,,,,1280,Staphylococcus aureus,,SA564,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,liver,secreted tyrosine phosphatase,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene mutation; gene complementation,,,YVS,30131335,PubMed,10.1074/jbc.RA118.003555,J Biol Chem. 2018 Oct 5;293(40):15569-15580,virginie.molle@univ-montp2.fr,Deletion of ptpA in S. aureus affected intramacrophage survival and infectivity.,L Gannoun-Zaki 2018,2018,1 gene,"Gannoun-Zaki-2018-PtpA, a secreted tyrosine ph",BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12127,PHI:8402,,no data found,,,,,,GX_XOC1459 (cheB1),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12128,PHI:8403,,no data found,,,,,,GX_XOC2117 (cheB2),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12129,PHI:8404,UniProt,A0A0C5V2Y1,GenBank,PUE92520,,,WHRI 5234,GX_XOC2221 (cheV),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12130,PHI:8405,,no data found,,,,,,GX_XOC3305 (colR) (vgrR),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12131,PHI:8406,,no data found,,,,,,GX_XOC3684 (hpaR2),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12132,PHI:8407,UniProt,Q9KH31,GenBank,PUE90398,,,WHRI 5234,GX_XOC3223 (hrpG),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12133,PHI:8408,UniProt,G7TFW1,GenBank,AEQ95317,,,BLS256,GX_XOC1041 (phoB),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12134,PHI:8409,UniProt,G7TBZ2,GenBank,AEQ97401,,,BLS256,GX_XOC3093 (pilG),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12135,PHI:8410,,no data found,,,,,,GX_XOC3092 (pilR),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12136,PHI:8411,,no data found,,,,,,GX_XOC2227 (ravR) (pdeR),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12137,PHI:8412,UniProt,G7TEN6,GenBank,AEQ96401,,,BLS256,GX_XOC2103 (rpfG),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12138,PHI:8413,,no data found,,,,,,GX_XOC3525 (tctD),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12139,PHI:8414,,no data found,,,,,,GX_XOC2201 (vemR),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation; gene complementation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12140,PHI:8415,UniProt,A0A0C5UKV3,GenBank,AJQ87735,,,CFBP7342,GX_XOC2338 (virG),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12141,PHI:8416,,no data found,,,,,,GX_XOC0722,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12142,PHI:8417,,no data found,,,,,,GX_XOC1206,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12143,PHI:8418,,no data found,,,,,,GX_XOC2451,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12144,PHI:8407,UniProt,Q9KH31,,,,,,GX_XOC3223 (hrpG),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12145,PHI:8414,,no data found,,,,,,GX_XOC2201 (vemR),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12146,PHI:8419,,no data found,,,,,,GX_XOC0329,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12147,PHI:8420,,no data found,,,,,,GX_XOC3947,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; CdSO4; H2O2; sodium dodecyl sulfate (SDS),NaCl: CHEBI:26710; CdSO4: CHEBI:50292; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation,,,YVS,30131784,PubMed,10.3389/fmicb.2018.01789,Front Microbiol. 2018 Aug 7;9:1789,yqhe@gxu.edu.cn,"Results showed that one mutant (insertion in hrpG) totally lost the ability to incite HR and 3 mutants (insertions in vemR, GX_XOC0329, and GX_XOC3947) performed weak HR (Figure 5B), suggesting these RR genes might be involved in regulation of T3SS system.",Z C Zhang 2018,2018,19 genes,Zhang-2018-Genome-Wide Screening for Novel Can,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12148,PHI:8421,UniProt,A0A0D8EM49,GenBank,KZA28837,,,AB3638,acrR,,,,,,,470,Acinetobacter baumannii,,ATCC 17903,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,local repressor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30131944,PubMed,10.3389/fcimb.2018.00270,Front Cell Infect Microbiol. 2018 Aug 7;8:270,choich@cnu.ac.kr,"The deletion of acrR resulted in increased motility, biofilm/pellicle formation and invasion in A. nosocomialis.",B Subhadra 2018,2018,1 gene,Subhadra-2018-Local Repressor AcrR Regulates A,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12149,PHI:8422,,no data found,GenBank,WP_116893338,,,,hopZ1a,,,,,,,317,Pseudomonas syringae,,pv. syringae strain 7B40,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Canadian Wonder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12150,PHI:8422,,no data found,GenBank,WP_116893338,,,,hopZ1a,,C216A,,,,,317,Pseudomonas syringae,264730,pv. phaseolicola strain 1448A,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Canadian Wonder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12151,PHI:8423,UniProt,Q48M21,GenBank,AAZ34495,,,1448A; BAA-978,hrcV,,,,,,,317,Pseudomonas syringae,264730,pv. phaseolicola strain 1448A,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Canadian Wonder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12152,PHI:8424,UniProt,Q48BD8,GenBank,AAZ37975,,,1448A; BAA-978,hopQ1,,,,,,,317,Pseudomonas syringae,264730,pv. phaseolicola strain 1448A,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Canadian Wonder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12153,PHI:8422,,no data found,GenBank,WP_116893338,,,,hopZ1a,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12154,PHI:8425,UniProt,Q8RP13,GenBank,WP_054080048,,,,hopZ1c,,,,,,,317,Pseudomonas syringae,629265,pv. maculicola strain ES4326,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12155,PHI:8422,,no data found,GenBank,WP_116893338,,,,hopZ1a,,,,,,,317,Pseudomonas syringae,264730,pv. phaseolicola strain 1448A,bacterial speck (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12156,PHI:8426,UniProt,Q4ZX47,GenBank,AAY36275,,,B728a,hopZ3,,,,,,,317,Pseudomonas syringae,264730,pv. phaseolicola strain 1448A,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12157,PHI:8426,UniProt,Q4ZX47,GenBank,AAY36275,,,B728a,hopZ3,,,,,,PHI:8427,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12158,PHI:8427,UniProt,Q4ZPS9,GenBank,AAY38843,,,B728a,HopAF1,,,,,,PHI:8426,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12159,PHI:8426,UniProt,Q4ZX47,GenBank,AAY36275,,,B728a,HopZ3,,,,,,PHI:8428,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12160,PHI:8428,UniProt,A0A0N8SZV2,GenBank,KPY75424,,,ICMP3023,HopAI1,,,,,,PHI:8426,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12161,PHI:8426,UniProt,Q4ZX47,GenBank,AAY36275,,,B728a,HopZ3,,,,,,PHI:8429,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12162,PHI:8429,UniProt,A0A0F7A7U6,GenBank,AKF53204,,,HS191,HopAG1,,,,,,PHI:8426,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12163,PHI:8426,UniProt,Q4ZX47,GenBank,AAY36275,,,B728a,HopZ3,,,,,,PHI:8430,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12164,PHI:8430,UniProt,Q4ZX82,GenBank,AAY36240,,,B728a,HopM1,,,,,,PHI:8426,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12165,PHI:8426,UniProt,Q4ZX47,GenBank,AAY36275,,,B728a,HopZ3,,,,,,PHI:8431,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12166,PHI:8431,UniProt,Q4ZX48,GenBank,AAY36274,,,B728a,HopX1,,,,,,PHI:8426,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12167,PHI:8426,UniProt,Q4ZX47,GenBank,AAY36275,,,B728a,HopZ3,,,,,,PHI:8432,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12168,PHI:8432,UniProt,Q4ZV89,GenBank,AAY36933,,,B728a,HopH1,,,,,,PHI:8426,317,Pseudomonas syringae,205918,pv. syringae strain B728a,bacterial speck (tomato),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30154802,PubMed,10.3389/fpls.2018.00977,Front Plant Sci. 2018 Aug 14;9:977,javieruizal@uma.es,"Both effectors, HopZ1a and HopZ3 triggered immunity in their plant hosts only when delivered from heterologous strains, while immunity is suppressed when delivered from their native strains.",J S Rufián 2018,2018,11 genes,Rufian-2018-Suppression of HopZ Effector-Trigg,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12169,PHI:8433,UniProt,A0A0H2XBP7,GenBank,AAY50846,,,8004,XC_3806 (rpoD),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-70 factor,,,,lethal,,,,,,,,reduced,,yes,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12170,PHI:8434,UniProt,A0A0H2XDA9,GenBank,AAY50883,,,8004,XC_3843 (rpoH),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-32 factor,,,,lethal,,,,,,,,reduced,,yes,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12171,PHI:8435,UniProt,A0A0H2X9L5,GenBank,AAY49335,,,8004,XC_2281 (fliA),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12172,PHI:8436,UniProt,A0A0H2X757,GenBank,AAY48380,,,8004,XC_1311 (rpoN1),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-54 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12173,PHI:8437,UniProt,A0A0H2X7T6,GenBank,AAY49306,,,8004,XC_2251 (rpoN2),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-54 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12174,PHI:8436,UniProt,A0A0H2X757,GenBank,AAY48380,,,8004,XC_1311 (rpoN1),,,,,,PHI:8437,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-54 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12175,PHI:8437,UniProt,A0A0H2X7T6,GenBank,AAY49306,,,8004,XC_2251 (rpoN2),,,,,,PHI:8436,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-54 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12176,PHI:8438,UniProt,A0A0H2XB69,GenBank,AAY50022,,,8004,XC_2974 (rpoE1),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-H factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12177,PHI:8439,UniProt,A0A0H2XAJ1,GenBank,AAY50427,,,8004,XC_3383 (rpoE2),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,ECF sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12178,PHI:8440,UniProt,A0A0H2X952,GenBank,AAY49953,,,8004,XC_2905 (rpoE3),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12179,PHI:8441,UniProt,A0A0H2X8J6,GenBank,AAY49616,,,8004,XC_2566 (rpoE4),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-E factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12180,PHI:8442,UniProt,A0A0H2X5J0,GenBank,AAY48542,,,8004,XC_1474 (rpoE5),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase ECF-type sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12181,PHI:8443,UniProt,A0A0H2X5G8,GenBank,AAY48262,,,8004,XC_1193 (rpoE6),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-70 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12182,PHI:8444,UniProt,A0A0H2XB36,GenBank,AAY49982,,,8004,XC_2934 (rpoE7),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12183,PHI:8445,UniProt,A0A0H2XBU6,GenBank,AAY50904,,,8004,XC_3864 (rpoE8),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12184,PHI:8446,UniProt,A0A0H2X3N4,GenBank,AAY47637,,,8004,XC_0556 (rpoE9),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12185,PHI:8447,UniProt,A0A0H2XA14,GenBank,AAY50145,,,8004,XC_3099 (rpoE10),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12186,PHI:8439,UniProt,A0A0H2XAJ1,GenBank,AAY50427,,,8004,XC_3383 (rpoE2),,,,,,PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,ECF sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12187,PHI:8440,UniProt,A0A0H2X952,GenBank,AAY49953,,,8004,XC_2905 (rpoE3),,,,,,PHI:8439; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12188,PHI:8441,UniProt,A0A0H2X8J6,GenBank,AAY49616,,,8004,XC_2566 (rpoE4),,,,,,PHI:8439; PHI:8440; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-E factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12189,PHI:8442,UniProt,A0A0H2X5J0,GenBank,AAY48542,,,8004,XC_1474 (rpoE5),,,,,,PHI:8439; PHI:8440; PHI:8441; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase ECF-type sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12190,PHI:8443,UniProt,A0A0H2X5G8,GenBank,AAY48262,,,8004,XC_1193 (rpoE6),,,,,,PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-70 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12191,PHI:8444,UniProt,A0A0H2XB36,GenBank,AAY49982,,,8004,XC_2934 (rpoE7),,,,,,PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12192,PHI:8445,UniProt,A0A0H2XBU6,GenBank,AAY50904,,,8004,XC_3864 (rpoE8),,,,,,PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12193,PHI:8446,UniProt,A0A0H2X3N4,GenBank,AAY47637,,,8004,XC_0556 (rpoE9),,,,,,PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12194,PHI:8447,UniProt,A0A0H2XA14,GenBank,AAY50145,,,8004,XC_3099 (rpoE10),,,,,,PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12195,PHI:8438,UniProt,A0A0H2XB69,GenBank,AAY50022,,,8004,XC_2974 (rpoE1),,,,,,PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-H factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12196,PHI:8439,UniProt,A0A0H2XAJ1,GenBank,AAY50427,,,8004,XC_3383 (rpoE2),,,,,,PHI:8438; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,ECF sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12197,PHI:8440,UniProt,A0A0H2X952,GenBank,AAY49953,,,8004,XC_2905 (rpoE3),,,,,,PHI:8438; PHI:8439; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12198,PHI:8441,UniProt,A0A0H2X8J6,GenBank,AAY49616,,,8004,XC_2566 (rpoE4),,,,,,PHI:8438; PHI:8439; PHI:8440; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-E factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12199,PHI:8442,UniProt,A0A0H2X5J0,GenBank,AAY48542,,,8004,XC_1474 (rpoE5),,,,,,PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase ECF-type sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12200,PHI:8443,UniProt,A0A0H2X5G8,GenBank,AAY48262,,,8004,XC_1193 (rpoE6),,,,,,PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-70 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12201,PHI:8444,UniProt,A0A0H2XB36,GenBank,AAY49982,,,8004,XC_2934 (rpoE7),,,,,,PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12202,PHI:8445,UniProt,A0A0H2XBU6,GenBank,AAY50904,,,8004,XC_3864 (rpoE8),,,,,,PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12203,PHI:8446,UniProt,A0A0H2X3N4,GenBank,AAY47637,,,8004,XC_0556 (rpoE9),,,,,,PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12204,PHI:8447,UniProt,A0A0H2XA14,GenBank,AAY50145,,,8004,XC_3099 (rpoE10),,,,,,PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12205,PHI:8435,UniProt,A0A0H2X9L5,GenBank,AAY49335,,,8004,XC_2281 (fliA),,,,,,PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12206,PHI:8438,UniProt,A0A0H2XB69,GenBank,AAY50022,,,8004,XC_2974 (rpoE1),,,,,,PHI:8435; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-H factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12207,PHI:8439,UniProt,A0A0H2XAJ1,GenBank,AAY50427,,,8004,XC_3383 (rpoE2),,,,,,PHI:8435; PHI:8438; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,ECF sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12208,PHI:8440,UniProt,A0A0H2X952,GenBank,AAY49953,,,8004,XC_2905 (rpoE3),,,,,,PHI:8435; PHI:8438; PHI:8439; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12209,PHI:8441,UniProt,A0A0H2X8J6,GenBank,AAY49616,,,8004,XC_2566 (rpoE4),,,,,,PHI:8435; PHI:8438; PHI:8439; PHI:8440; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-E factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12210,PHI:8442,UniProt,A0A0H2X5J0,GenBank,AAY48542,,,8004,XC_1474 (rpoE5),,,,,,PHI:8435; PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8443; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase ECF-type sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12211,PHI:8443,UniProt,A0A0H2X5G8,GenBank,AAY48262,,,8004,XC_1193 (rpoE6),,,,,,PHI:8435; PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8444; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma-70 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12212,PHI:8444,UniProt,A0A0H2XB36,GenBank,AAY49982,,,8004,XC_2934 (rpoE7),,,,,,PHI:8435; PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8445; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12213,PHI:8445,UniProt,A0A0H2XBU6,GenBank,AAY50904,,,8004,XC_3864 (rpoE8),,,,,,PHI:8435; PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8446; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12214,PHI:8446,UniProt,A0A0H2X3N4,GenBank,AAY47637,,,8004,XC_0556 (rpoE9),,,,,,PHI:8435; PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8447,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12215,PHI:8447,UniProt,A0A0H2XA14,GenBank,AAY50145,,,8004,XC_3099 (rpoE10),,,,,,PHI:8435; PHI:8438; PHI:8439; PHI:8440; PHI:8441; PHI:8442; PHI:8443; PHI:8444; PHI:8445; PHI:8446,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,The data suggested that the sigma70 factor RpoE1 was required for Xcc full virulence.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12216,PHI:8448,UniProt,Q8P8Y0,GenBank,AAM41388,,,ATCC 33913,AvrBs1,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,"An AvrBs1-defective mutant, was also unable to elicit visible HR symptoms in the pepper cultivar ECW-10R.",L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12217,PHI:8438,UniProt,A0A0H2XB69,GenBank,AAY50022,,,8004,rpoE1,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,RNA polymerase sigma-H factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30123197,PubMed,10.3389/fmicb.2018.01749,Front Microbiol. 2018 Aug 3;9:1749,jltang@gxu.edu.cn,A rpoE1-defective strain showed weaker HR symptoms when compared to those elicited by the wild-type.,L Y Yang 2018,2018,16 genes,Yang-2018-Systematic Functional Analysis of Si,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12218,PHI:8449,,no data found,GenBank,AIK79119,,,ATCC 43816 KPPR1,kvrA (VK055_0496),,,,,,,573,Klebsiella pneumoniae,,KPPR1S,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12219,PHI:8449,,no data found,GenBank,AIK79119,,,ATCC 43816 KPPR1,kvrA (VK055_0496),,,,,,,573,Klebsiella pneumoniae,,NTUH-K2044,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12220,PHI:8449,,no data found,GenBank,AIK79119,,,ATCC 43816 KPPR1,kvrA (VK055_0496),,,,,,,573,Klebsiella pneumoniae,,MKP103,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12221,PHI:8449,,no data found,GenBank,AIK79119,,,ATCC 43816 KPPR1,kvrA (VK055_0496),,,,,,,573,Klebsiella pneumoniae,,KPPR1S,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12222,PHI:8449,,no data found,GenBank,AIK79119,,,ATCC 43816 KPPR1,kvrA (VK055_0496),,,,,,,573,Klebsiella pneumoniae,,NTUH-K2044,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12223,PHI:8449,,no data found,GenBank,AIK79119,,,ATCC 43816 KPPR1,kvrA (VK055_0496),,,,,,,573,Klebsiella pneumoniae,,MKP103,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12224,PHI:8450,UniProt,A0A1Y0PXE8,GenBank,ATN99238,,,ST2017:950142398,kvrB (VK055_4504),,,,,,,573,Klebsiella pneumoniae,,KPPR1S,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12225,PHI:8450,UniProt,A0A1Y0PXE8,GenBank,ATN99238,,,ST2017:950142398,kvrB (VK055_4504),,,,,,,573,Klebsiella pneumoniae,,NTUH-K2044,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12226,PHI:8450,UniProt,A0A1Y0PXE8,GenBank,ATN99238,,,ST2017:950142398,kvrB (VK055_4504),,,,,,,573,Klebsiella pneumoniae,,MKP103,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12227,PHI:8450,UniProt,A0A1Y0PXE8,GenBank,ATN99238,,,ST2017:950142398,kvrB (VK055_4504),,,,,,,573,Klebsiella pneumoniae,,KPPR1S,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,transcriptional repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12228,PHI:8450,UniProt,A0A1Y0PXE8,GenBank,ATN99238,,,ST2017:950142398,kvrB (VK055_4504),,,,,,,573,Klebsiella pneumoniae,,NTUH-K2044,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,transcriptional repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12229,PHI:8450,UniProt,A0A1Y0PXE8,GenBank,ATN99238,,,ST2017:950142398,kvrB (VK055_4504),,,,,,,573,Klebsiella pneumoniae,,MKP103,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,transcriptional repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30087173,PubMed,10.1128/mBio.01443-18,MBio. 2018 Aug 7;9(4). pii: e01443-18,vlmiller@med.unc.edu,KvrA and KvrB affected virulence in classical and hv strains but the effect on virulence may not be exclusively due to effects on capsule production.,M Palacios 2018,2018,2 genes,Palacios-2018-Identification of Two Regulators,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12230,PHI:8451,UniProt,A6SDQ3,GenBank,ATZ47391,,,B05.10,Bcatg4 (Bcin02g06770),chromosome BCIN02,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,cysteine protease,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30167777,PubMed,10.1007/s00294-018-0882-0,Curr Genet. 2018 Aug 30,zhma@zju.edu.cn,"Targeted gene deletion of Bcatg4 (ΔBcatg4) led to autophagy blocking and a significant retardation in growth and conidiation, in addition ΔBcatg4 failed to form sclerotia.",N Liu 2018,2018,1 gene,Liu-2018-Involvement of the cysteine protease,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12231,PHI:8451,UniProt,A6SDQ3,GenBank,ATZ47391,,,B05.10,Bcatg4 (Bcin02g06770),chromosome BCIN02,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,cysteine protease,,,,loss of pathogenicity,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30167777,PubMed,10.1007/s00294-018-0882-0,Curr Genet. 2018 Aug 30,zhma@zju.edu.cn,"Targeted gene deletion of Bcatg4 (ΔBcatg4) led to autophagy blocking and a significant retardation in growth and conidiation, in addition ΔBcatg4 failed to form sclerotia.",N Liu 2018,2018,1 gene,Liu-2018-Involvement of the cysteine protease,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12232,PHI:8452,UniProt,Q9I2P8,GenBank,AE004611_1,,,PAO1,nfuA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,Fe/S biogenesis protein,,,,reduced virulence,,,,,,reduced,,,,no,"plumbagin (PB); menadione (MD); paraquat (PQ); N-ethylmaleimide (NEM); cumene hydroperoxide [CuOOH]; tert-butyl hydroperoxide [tBOOH]; hydrogen peroxide [H2O2]; sodium hypochlorite (NaOCl); 2,2'-dipyridyl; FeCl3; CuCl2; CdCl2; CoCl2","plumbagin (PB): CHEBI:8273; menadione (MD): CHEBI:28869; paraquat (PQ): CHEBI:34905; N-ethylmaleimide (NEM): CHEBI:44485; cumene hydroperoxide [CuOOH]: CHEBI:78673; tert-butyl hydroperoxide [tBOOH]: CHEBI:64090; hydrogen peroxide [H2O2]: CHEBI:16240; sodium hypochlorite (NaOCl): CHEBI:32146; 2,2'-dipyridyl: CHEBI:30351; FeCl3: CHEBI:30808; CuCl2: CHEBI:49553; CdCl2: CHEBI:35456; CoCl2: CHEBI:35696",,,,,gene mutation: characterised; gene complementation,,,YVS,30092083,PubMed,10.1371/journal.pone.0202151,PLoS One. 2018 Aug 9;13(8):e0202151,skorn@cri.or.th,Site directed mutagenesis analysis revealed that the conserved CXXC motif of the Nfu-type scaffold protein domain at the N-terminus was required for the NfuA functions in conferring the stress resistance phenotype.,A Romsang 2018,2018,1 gene,Romsang-2018-Pseudomonas aeruginosa nfuA_ Gene,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12233,PHI:8453,UniProt,P0C0F7,GenBank,AAY49386,,,8004,rpfC,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain Xc1,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,sensory/regulatory protein,,,DSF-family signal biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30156480,PubMed,10.1094/MPMI-07-18-0187-R,Mol Plant Microbe Interact. 2018 Aug 29,yinyue_deng@hotmail.com,"Exogenous addition of cabbage juice that contains large amounts of sucrose and glucose to the rpfC deletion mutant, which overproduces DSF-family signals, slightly increased the bacterial growth rate.",C Zhang 2018,2018,1 gene,Zhang-2018-Xanthomonas campestris promotes dif,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12234,PHI:8454,UniProt,A0A384JD52,GenBank,XP_001549887,,,B05.10,BcMkk1,chromosome 3,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12235,PHI:8454,UniProt,A0A384JD52,GenBank,XP_001549887,,,B05.10,BcMkk1,chromosome 3,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12236,PHI:8454,UniProt,A0A384JD52,GenBank,XP_001549887,,,B05.10,BcMkk1,chromosome 3,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12237,PHI:8454,UniProt,A0A384JD52,GenBank,XP_001549887,,,B05.10,BcMkk1,chromosome 3,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12238,PHI:8455,,no data found,GenBank,XP_024547231,,,B05.10,BcBck1,chromosome 2,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12239,PHI:8455,,no data found,GenBank,XP_024547231,,,B05.10,BcBck1,chromosome 2,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12240,PHI:8455,,no data found,GenBank,XP_024547231,,,B05.10,BcBck1,chromosome 2,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12241,PHI:8455,,no data found,GenBank,XP_024547231,,,B05.10,BcBck1,chromosome 2,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12242,PHI:8456,UniProt,A0A384JS06,GenBank,XP_001554555,,,B05.10,BcBmp3,chromosome 9,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12243,PHI:8456,UniProt,A0A384JS06,GenBank,XP_001554555,,,B05.10,BcBmp3,chromosome 9,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12244,PHI:8456,UniProt,A0A384JS06,GenBank,XP_001554555,,,B05.10,BcBmp3,chromosome 9,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12245,PHI:8456,UniProt,A0A384JS06,GenBank,XP_001554555,,,B05.10,BcBmp3,chromosome 9,,,,,,40559,Botrytis cinerea,,38B1,grey mold,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,MAPK kinase,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,reduced,no,Congo red; H2O2; paraquat,Congo red: CHEBI:34653; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,30212570,PubMed,10.1371/journal.ppat.1007285,PLoS Pathog. 2018 Sep 13;14(9):e1007285,zhma@zju.edu.cn,"ΔBcMkk1 exhibited higher virulence than ΔBcBck1 and ΔBcBmp3, although ΔBcMkk1 displayed more serious defects than the latter in mycelial growth, conidiation, sensitivity to cell wall and oxidative stresses.",Y Yin 2018,2018,3 genes,Yin-2018-The MAPK kinase BcMkk1 suppresses oxa,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12246,PHI:8457,,no data found,,,,,,VmPacC,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; SDS; Congo red; NaCl,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,30190714,PubMed,10.3389/fmicb.2018.01981,Front Microbiol. 2018 Aug 23;9:1981,huanglili@nwsuaf.edu.cn,Expression of pectinase genes increased in deletion mutant during infection.,Y Wu 2018,2018,1 gene,Wu-2018-VmPacC Is Required for Acidification a,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12247,PHI:8458,UniProt,A0A165VNS8,GenBank,AMZ00811,,,CQMa 102,MaADH1,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,wing,ethanol dehydrogenase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30186258,PubMed,10.3389/fmicb.2018.01932,Front Microbiol. 2018 Aug 21;9:1932,yuxianxia@cqu.edu.cn,MaADH1 was critical to growth and sporulation under hypoxic stress by detoxification of acetaldehyde in M. acridum.,E Zhang 2018,2018,1 gene,Zhang-2018-Ethanol Dehydrogenase I Contributes,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12248,PHI:8458,UniProt,A0A165VNS8,GenBank,AMZ00811,,,CQMa 102,MaADH1,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,monocots,4530,Oryza sativa (related: rice),,,,caryopsis,ethanol dehydrogenase,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30186258,PubMed,10.3389/fmicb.2018.01932,Front Microbiol. 2018 Aug 21;9:1932,yuxianxia@cqu.edu.cn,MaADH1 was critical to growth and sporulation under hypoxic stress by detoxification of acetaldehyde in M. acridum.,E Zhang 2018,2018,1 gene,Zhang-2018-Ethanol Dehydrogenase I Contributes,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12249,PHI:8459,UniProt,G4MPF4,GenBank,EHA57996,,,70-15,crf1 (MGG_05709),chromosome 1,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast,monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,basic helix-loop-helix transcription factor,,,,loss of pathogenicity,,yes,,,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30126031,PubMed,10.1111/1462-2920.14387,Environ Microbiol. 2018 Sep;20(9):3427-3441,jplu@zju.edu.cn,"CRF1 was essential for peroxisome and vacuole function, and conidial cell death during appressorium formation.",H Cao 2018,2018,1 gene,Cao-2018-The basic helix-loop-helix transcript,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12250,PHI:8459,UniProt,G4MPF4,GenBank,EHA57996,,,70-15,crf1 (MGG_05709),chromosome 1,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast,monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,basic helix-loop-helix transcription factor,,,,loss of pathogenicity,,yes,yes,yes,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30126031,PubMed,10.1111/1462-2920.14387,Environ Microbiol. 2018 Sep;20(9):3427-3441,jplu@zju.edu.cn,"CRF1 was essential for peroxisome and vacuole function, and conidial cell death during appressorium formation.",H Cao 2018,2018,1 gene,Cao-2018-The basic helix-loop-helix transcript,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12251,PHI:8460,UniProt,B0Y650,GenBank,EDP50235,,,A1163,prx1 (AFUB_065670),,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,peroxiredoxin,,,,reduced virulence,,,,,,,,wild type,wild type,no,H2O2; paraquat; menadione; rotenone; antimycin A; FCCP [carbonyl cyanide 4-trifluoromethoxy) phenylhydrazone]; malonate; oligomycin; SHAM (salicylhydroxamic acid); fludioxonil; iprodione,"H2O2: CHEBI:16240; paraquat: CHEBI:34905; menadione: CHEBI:28869; rotenone: CHEBI:28201; antimycin A: CHEBI:22584; FCCP [carbonyl cyanide 4-trifluoromethoxy) phenylhydrazone]: CHEBI:75458; malonic acid: CHEBI:30794; oligomycin: CHEBI:25675; salicylhydroxamic acid (SHAM): CHEBI:45615; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7",,,,,gene deletion: full; gene complementation,,,YVS,30120327,PubMed,10.1038/s41598-018-30108-2,Sci Rep. 2018 Aug 17;8(1):12314,imalavazi@ufscar.br,Cytosolic Prx1 was important for A. fumigatus survival upon electron transport dysfunction.,M C Rocha 2018,2018,3 genes,Rocha-2018-Analyses of the three 1-Cys Peroxir,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12252,PHI:8461,UniProt,B0Y2W1,GenBank,EDP52217,,,A1163,prxB (AFUB_062560),,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,peroxiredoxin,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,H2O2; paraquat; menadione; rotenone; antimycin A; FCCP [carbonyl cyanide 4-trifluoromethoxy) phenylhydrazone]; malonate; oligomycin; SHAM (salicylhydroxamic acid); fludioxonil; iprodione,"H2O2: CHEBI:16240; paraquat: CHEBI:34905; menadione: CHEBI:28869; rotenone: CHEBI:28201; antimycin A: CHEBI:22584; FCCP [carbonyl cyanide 4-trifluoromethoxy) phenylhydrazone]: CHEBI:75458; malonic acid: CHEBI:30794; oligomycin: CHEBI:25675; salicylhydroxamic acid (SHAM): CHEBI:45615; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7",,,,,gene deletion: full; gene complementation,,,YVS,30120327,PubMed,10.1038/s41598-018-30108-2,Sci Rep. 2018 Aug 17;8(1):12314,imalavazi@ufscar.br,Cytosolic Prx1 was important for A. fumigatus survival upon electron transport dysfunction.,M C Rocha 2018,2018,3 genes,Rocha-2018-Analyses of the three 1-Cys Peroxir,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12253,PHI:8462,UniProt,B0Y9D7,GenBank,EDP48630,,,A1163,prxC (AFUB_080670),,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,peroxiredoxin,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,H2O2; paraquat; menadione; rotenone; antimycin A; FCCP [carbonyl cyanide 4-trifluoromethoxy) phenylhydrazone]; malonate; oligomycin; SHAM (salicylhydroxamic acid); fludioxonil; iprodione,"H2O2: CHEBI:16240; paraquat: CHEBI:34905; menadione: CHEBI:28869; rotenone: CHEBI:28201; antimycin A: CHEBI:22584; FCCP [carbonyl cyanide 4-trifluoromethoxy) phenylhydrazone]: CHEBI:75458; malonic acid: CHEBI:30794; oligomycin: CHEBI:25675; salicylhydroxamic acid (SHAM): CHEBI:45615; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909, CAS:36734-19-7",,,,,gene deletion: full; gene complementation,,,YVS,30120327,PubMed,10.1038/s41598-018-30108-2,Sci Rep. 2018 Aug 17;8(1):12314,imalavazi@ufscar.br,Cytosolic Prx1 was important for A. fumigatus survival upon electron transport dysfunction.,M C Rocha 2018,2018,3 genes,Rocha-2018-Analyses of the three 1-Cys Peroxir,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12254,PHI:8463,UniProt,E9EJ76,GenBank,EFZ03762,,,ARSEF 23,sod1,,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Cu-superoxide dismutase,,,,reduced virulence,,,,,,,,,wild type,no,mendione; H2O2; calcofluor white,mendione: CHEBI:28869; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,30120522,PubMed,10.1007/s00253-018-9302-0,Appl Microbiol Biotechnol. 2018 Nov;102(21):9221-9230,mgfeng@zju.edu.cn,"The three mutants Δsod1, Δsod2 and Δsod3 suffered defects in conidial thermotolerance, UVB resistance and virulence.",X G Zhu 2018,2018,6 genes,Zhu-2018-Antioxidant activities of four supero,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12255,PHI:8464,UniProt,E9EXK0,GenBank,EFY99820,,,ARSEF 23,sod2,,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Mn-superoxide dismutase,,,,reduced virulence,,,,,,,,,reduced,no,mendione; H2O2; calcofluor white,mendione: CHEBI:28869; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,30120522,PubMed,10.1007/s00253-018-9302-0,Appl Microbiol Biotechnol. 2018 Nov;102(21):9221-9230,mgfeng@zju.edu.cn,"The three mutants Δsod1, Δsod2 and Δsod3 suffered defects in conidial thermotolerance, UVB resistance and virulence.",X G Zhu 2018,2018,6 genes,Zhu-2018-Antioxidant activities of four supero,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12256,PHI:8465,UniProt,E9EZI4,GenBank,EFY99375,,,ARSEF 23,sod3,,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Mn-superoxide dismutase,,,,reduced virulence,,,,,,,,,wild type,no,mendione; H2O2; calcofluor white,mendione: CHEBI:28869; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,30120522,PubMed,10.1007/s00253-018-9302-0,Appl Microbiol Biotechnol. 2018 Nov;102(21):9221-9230,mgfeng@zju.edu.cn,"The three mutants Δsod1, Δsod2 and Δsod3 suffered defects in conidial thermotolerance, UVB resistance and virulence.",X G Zhu 2018,2018,6 genes,Zhu-2018-Antioxidant activities of four supero,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12257,PHI:8466,UniProt,E9EWH3,GenBank,EFZ00595,,,ARSEF 23,sod4,,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Fe-superoxide dismutase,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full; gene complementation,,,YVS,30120522,PubMed,10.1007/s00253-018-9302-0,Appl Microbiol Biotechnol. 2018 Nov;102(21):9221-9230,mgfeng@zju.edu.cn,"The three mutants Δsod1, Δsod2 and Δsod3 suffered defects in conidial thermotolerance, UVB resistance and virulence.",X G Zhu 2018,2018,6 genes,Zhu-2018-Antioxidant activities of four supero,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12258,PHI:8467,UniProt,E9EVU3,GenBank,EFZ00365,,,ARSEF 23,sod5,,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Cu-superoxide dismutase,,,,unaffected pathogenicity,,,,,,,,,wild type,no,mendione; H2O2; calcofluor white,mendione: CHEBI:28869; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,30120522,PubMed,10.1007/s00253-018-9302-0,Appl Microbiol Biotechnol. 2018 Nov;102(21):9221-9230,mgfeng@zju.edu.cn,"The three mutants Δsod1, Δsod2 and Δsod3 suffered defects in conidial thermotolerance, UVB resistance and virulence.",X G Zhu 2018,2018,6 genes,Zhu-2018-Antioxidant activities of four supero,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12259,PHI:8468,UniProt,E9FDG4,GenBank,EFY94215,,,ARSEF 23,sod6,,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Cu-superoxide dismutase,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full; gene complementation,,,YVS,30120522,PubMed,10.1007/s00253-018-9302-0,Appl Microbiol Biotechnol. 2018 Nov;102(21):9221-9230,mgfeng@zju.edu.cn,"The three mutants Δsod1, Δsod2 and Δsod3 suffered defects in conidial thermotolerance, UVB resistance and virulence.",X G Zhu 2018,2018,6 genes,Zhu-2018-Antioxidant activities of four supero,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12260,PHI:8469,UniProt,A0A1S6XZH9,GenBank,AQX36265,,,,CpSep1,,,,,,,5116,Cryphonectria parasitica,660469,EP155/2,blight (chestnut),eudicots,21020,Castanea sativa (related: chestnut),,,,bark,hypovirus-regulated septin component,,,,reduced virulence,,,,,,increased; aberrant,,reduced; aberrant,wild type,no,mendione; sorbitol,mendione: CHEBI:28869; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30133338,PubMed,10.1094/MPMI-07-18-0194-R,Mol Plant Microbe Interact. 2018 Aug 22,dhkim@jbnu.ac.kr,The inhibition of colonial growth was partially recovered when the CpSep1-null mutants were cultured in the presence of the osmostabilizing sorbitol.,M Jo 2018,2018,1 gene,Jo-2018-Characterization of a Hypovirus-Regula,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12261,PHI:8469,UniProt,A0A1S6XZH9,GenBank,AQX36265,,,,CpSep1,,,,,,,5116,Cryphonectria parasitica,660469,EP155/2,blight (chestnut),eudicots,3750,Malus domestica (related: apple),,,,fruit,hypovirus-regulated septin component,,,,reduced virulence,,,,,,increased; aberrant,,reduced; aberrant,wild type,no,mendione; sorbitol,mendione: CHEBI:28869; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30133338,PubMed,10.1094/MPMI-07-18-0194-R,Mol Plant Microbe Interact. 2018 Aug 22,dhkim@jbnu.ac.kr,The inhibition of colonial growth was partially recovered when the CpSep1-null mutants were cultured in the presence of the osmostabilizing sorbitol.,M Jo 2018,2018,1 gene,Jo-2018-Characterization of a Hypovirus-Regula,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12262,PHI:8470,UniProt,A0A0B7KV51,GenBank,AUB33215,,,19F,galU,,,,,,,1313,Streptococcus pneumoniae,,85,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,pyrophosphorylase,,,biosynthesis of capsular polysaccharides,reduced virulence,,,,,,,,,,no,erythromycin; amoxicillin; doxycycline; cefuroxime; moxifloxacin; gentamicin,erythromycin: CHEBI:48923; amoxicillin: CHEBI:2676; doxycycline: CHEBI:50845; cefuroxime: CHEBI:3515; moxifloxacin: CHEBI:63611; gentamicin: CHEBI:17833,,,,,gene deletion: partial,,,YVS,30215741,PubMed,10.1093/femspd/fty069,Pathog Dis. 2018 Oct 1;76(7),paul.cos@uantwerpen.be,"Mutation improved streptococcal adherence to epithelial cells and macrophage phagocytosis in vitro, while there was no definitive correlation on biofilm formation between parent and mutant strains.",F Cools 2018,2018,1 gene,Cools-2018-Streptococcus pneumoniae galU gene,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12263,PHI:8470,UniProt,A0A0B7KV51,GenBank,AUB33215,,,19F,galU,,,,,,,1313,Streptococcus pneumoniae,,85,pneumococcal pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,pyrophosphorylase,,,biosynthesis of capsular polysaccharides,reduced virulence,,,,,,,,,,no,erythromycin; amoxicillin; doxycycline; cefuroxime; moxifloxacin; gentamicin,erythromycin: CHEBI:48923; amoxicillin: CHEBI:2676; doxycycline: CHEBI:50845; cefuroxime: CHEBI:3515; moxifloxacin: CHEBI:63611; gentamicin: CHEBI:17833,,,,,gene deletion: partial,,,YVS,30215741,PubMed,10.1093/femspd/fty069,Pathog Dis. 2018 Oct 1;76(7),paul.cos@uantwerpen.be,"Mutation improved streptococcal adherence to epithelial cells and macrophage phagocytosis in vitro, while there was no definitive correlation on biofilm formation between parent and mutant strains.",F Cools 2018,2018,1 gene,Cools-2018-Streptococcus pneumoniae galU gene,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12264,PHI:8470,UniProt,A0A0B7KV51,GenBank,AUB33215,,,19F,galU,,,,,,,1313,Streptococcus pneumoniae,,88,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,pyrophosphorylase,,,biosynthesis of capsular polysaccharides,reduced virulence,,,,,,,,,,no,erythromycin; amoxicillin; doxycycline; cefuroxime; moxifloxacin; gentamicin,erythromycin: CHEBI:48923; amoxicillin: CHEBI:2676; doxycycline: CHEBI:50845; cefuroxime: CHEBI:3515; moxifloxacin: CHEBI:63611; gentamicin: CHEBI:17833,,,,,gene deletion: partial,,,YVS,30215741,PubMed,10.1093/femspd/fty069,Pathog Dis. 2018 Oct 1;76(7),paul.cos@uantwerpen.be,"Mutation improved streptococcal adherence to epithelial cells and macrophage phagocytosis in vitro, while there was no definitive correlation on biofilm formation between parent and mutant strains.",F Cools 2018,2018,1 gene,Cools-2018-Streptococcus pneumoniae galU gene,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12265,PHI:8470,UniProt,A0A0B7KV51,GenBank,AUB33215,,,19F,galU,,,,,,,1313,Streptococcus pneumoniae,,88,pneumococcal pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,pyrophosphorylase,,,biosynthesis of capsular polysaccharides,reduced virulence,,,,,,,,,,no,erythromycin; amoxicillin; doxycycline; cefuroxime; moxifloxacin; gentamicin,erythromycin: CHEBI:48923; amoxicillin: CHEBI:2676; doxycycline: CHEBI:50845; cefuroxime: CHEBI:3515; moxifloxacin: CHEBI:63611; gentamicin: CHEBI:17833,,,,,gene deletion: partial,,,YVS,30215741,PubMed,10.1093/femspd/fty069,Pathog Dis. 2018 Oct 1;76(7),paul.cos@uantwerpen.be,"Mutation improved streptococcal adherence to epithelial cells and macrophage phagocytosis in vitro, while there was no definitive correlation on biofilm formation between parent and mutant strains.",F Cools 2018,2018,1 gene,Cools-2018-Streptococcus pneumoniae galU gene,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12266,PHI:8470,UniProt,A0A0B7KV51,GenBank,AUB33215,,,19F,galU,,,,,,,1313,Streptococcus pneumoniae,,serotype 3 strain M23,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,pyrophosphorylase,,,biosynthesis of capsular polysaccharides,reduced virulence,,,,,,,,,,no,erythromycin; amoxicillin; doxycycline; cefuroxime; moxifloxacin; gentamicin,erythromycin: CHEBI:48923; amoxicillin: CHEBI:2676; doxycycline: CHEBI:50845; cefuroxime: CHEBI:3515; moxifloxacin: CHEBI:63611; gentamicin: CHEBI:17833,,,,,gene deletion: partial,,,YVS,30215741,PubMed,10.1093/femspd/fty069,Pathog Dis. 2018 Oct 1;76(7),paul.cos@uantwerpen.be,"Mutation improved streptococcal adherence to epithelial cells and macrophage phagocytosis in vitro, while there was no definitive correlation on biofilm formation between parent and mutant strains.",F Cools 2018,2018,1 gene,Cools-2018-Streptococcus pneumoniae galU gene,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12267,PHI:8470,UniProt,A0A0B7KV51,GenBank,AUB33215,,,19F,galU,,,,,,,1313,Streptococcus pneumoniae,,serotype 3 strain M23,pneumococcal pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,pyrophosphorylase,,,biosynthesis of capsular polysaccharides,reduced virulence,,,,,,,,,,no,erythromycin; amoxicillin; doxycycline; cefuroxime; moxifloxacin; gentamicin,erythromycin: CHEBI:48923; amoxicillin: CHEBI:2676; doxycycline: CHEBI:50845; cefuroxime: CHEBI:3515; moxifloxacin: CHEBI:63611; gentamicin: CHEBI:17833,,,,,gene deletion: partial,,,YVS,30215741,PubMed,10.1093/femspd/fty069,Pathog Dis. 2018 Oct 1;76(7),paul.cos@uantwerpen.be,"Mutation improved streptococcal adherence to epithelial cells and macrophage phagocytosis in vitro, while there was no definitive correlation on biofilm formation between parent and mutant strains.",F Cools 2018,2018,1 gene,Cools-2018-Streptococcus pneumoniae galU gene,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12268,PHI:8470,UniProt,A0A0B7KV51,GenBank,AUB33215,,,19F,galU,,,,,,,1313,Streptococcus pneumoniae,171101,R6,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,pyrophosphorylase,,,biosynthesis of capsular polysaccharides,reduced virulence,,,,,,,,,,no,erythromycin; amoxicillin; doxycycline; cefuroxime; moxifloxacin; gentamicin,erythromycin: CHEBI:48923; amoxicillin: CHEBI:2676; doxycycline: CHEBI:50845; cefuroxime: CHEBI:3515; moxifloxacin: CHEBI:63611; gentamicin: CHEBI:17833,,,,,gene deletion: partial,,,YVS,30215741,PubMed,10.1093/femspd/fty069,Pathog Dis. 2018 Oct 1;76(7),paul.cos@uantwerpen.be,"Mutation improved streptococcal adherence to epithelial cells and macrophage phagocytosis in vitro, while there was no definitive correlation on biofilm formation between parent and mutant strains.",F Cools 2018,2018,1 gene,Cools-2018-Streptococcus pneumoniae galU gene,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12269,PHI:8470,UniProt,A0A0B7KV51,GenBank,AUB33215,,,19F,galU,,,,,,,1313,Streptococcus pneumoniae,171101,R6,pneumococcal pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,pyrophosphorylase,,,biosynthesis of capsular polysaccharides,reduced virulence,,,,,,,,,,no,erythromycin; amoxicillin; doxycycline; cefuroxime; moxifloxacin; gentamicin,erythromycin: CHEBI:48923; amoxicillin: CHEBI:2676; doxycycline: CHEBI:50845; cefuroxime: CHEBI:3515; moxifloxacin: CHEBI:63611; gentamicin: CHEBI:17833,,,,,gene deletion: partial,,,YVS,30215741,PubMed,10.1093/femspd/fty069,Pathog Dis. 2018 Oct 1;76(7),paul.cos@uantwerpen.be,"Mutation improved streptococcal adherence to epithelial cells and macrophage phagocytosis in vitro, while there was no definitive correlation on biofilm formation between parent and mutant strains.",F Cools 2018,2018,1 gene,Cools-2018-Streptococcus pneumoniae galU gene,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12270,PHI:8471,,no data found,GenBank,PVW94661,,,CAMSA2050,Hcp,,Arg30Ala,,,,,197,Campylobacter jejuni,,,gastroenteritis,primates,9606,Homo sapiens (related: human),Hep-G2 cell line,,,Hep-G2 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,30194714,PubMed,10.1111/febs.14650,FEBS J. 2018 Sep 7,habib@comsats.edu.pk,The extended loop region in Hcp-Cj was important in inducing cytotoxicity in HepG2 cells but had no influence on biofilm formation in C. jejuni. liver hepatocellular carcinoma cells,Z Noreen 2018,2018,1 gene,Noreen-2018-Structural basis for the pathogene,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12271,PHI:8472,UniProt,A0A2Z5YNZ6,GenBank,BBC68983,,,ATCC 927,eccCb1,,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12272,PHI:8473,UniProt,B2HMS9,GenBank,ACC43848,,,M,espG1 (MMAR_5441),,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12273,PHI:8474,UniProt,B2HMT0,GenBank,ACC43849,,,M,espH (MMAR_5442),,,,espE (MMAR_5439),UniProt: B2HMS7; GenBank: ACC43846,,1781,Mycobacterium marinum,,M USA,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,accessory ESX-1 protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12274,PHI:8475,UniProt,B2HMT1,GenBank,ACC43850,,,M,eccA1 (MMAR_5443),,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,accessory ESX-1 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12275,PHI:8472,UniProt,A0A2Z5YNZ6,GenBank,BBC68983,,,ATCC 927,eccCb1,,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12276,PHI:8473,UniProt,B2HMS9,GenBank,ACC43848,,,M,espG1 (MMAR_5441),,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12277,PHI:8474,UniProt,B2HMT0,GenBank,ACC43849,,,M,espH (MMAR_5442),,,,espE (MMAR_5439),UniProt: B2HMS7; GenBank: ACC43846,,1781,Mycobacterium marinum,,M USA,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12278,PHI:8475,UniProt,B2HMT1,GenBank,ACC43850,,,M,eccA1 (MMAR_5443),,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12279,PHI:8472,UniProt,A0A2Z5YNZ6,GenBank,BBC68983,,,ATCC 927,eccCb1,,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12280,PHI:8473,UniProt,B2HMS9,GenBank,ACC43848,,,M,espG1 (MMAR_5441),,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12281,PHI:8474,UniProt,B2HMT0,GenBank,ACC43849,,,M,espH (MMAR_5442),,,,espE (MMAR_5439),UniProt: B2HMS7; GenBank: ACC43846,,1781,Mycobacterium marinum,,M USA,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,accessory ESX-1 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12282,PHI:8475,UniProt,B2HMT1,GenBank,ACC43850,,,M,eccA1 (MMAR_5443),,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,accessory ESX-1 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12283,PHI:8472,UniProt,A0A2Z5YNZ6,GenBank,BBC68983,,,ATCC 927,eccCb1,,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12284,PHI:8473,UniProt,B2HMS9,GenBank,ACC43848,,,M,espG1 (MMAR_5441),,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12285,PHI:8474,UniProt,B2HMT0,GenBank,ACC43849,,,M,espH (MMAR_5442),,,,espE (MMAR_5439),UniProt: B2HMS7; GenBank: ACC43846,,1781,Mycobacterium marinum,,M USA,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12286,PHI:8475,UniProt,B2HMT1,GenBank,ACC43850,,,M,eccA1 (MMAR_5443),,,,,,,1781,Mycobacterium marinum,,M USA,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,accessory ESX-1 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30102741,PubMed,10.1371/journal.ppat.1007247,PLoS Pathog. 2018 Aug 13;14(8):e1007247,w.bitter@vumc.nl,"The ΔespH mutant seemed to have a host-specific or invivo-specific effect, illustrated by a hypervirulent phenotype seen in zebrafish larvae, but not in cell infections in vitro.",T H Phan 2018,2018,4 genes,Phan-2018-EspH is a hypervirulence factor for,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12287,PHI:8476,,no data found,,,,,,MPR1,,MPR1QG,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,primates,9606,Homo sapiens (related: human),hCMEC/D3 cell line,,,HCMEC/D3 cell,secreted metalloprotease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30161190,PubMed,10.1371/journal.pone.0203020,PLoS One. 2018 Aug 30;13(8):e0203020,acgelli@ucdavis.edu,"The study identified the prodomain cleavage sites of Mpr1 and demonstrated that when mutated, the prodomain appears to remain attached to the catalytic C-terminus of Mpr1 rendering a nonfunctional Mpr1 protein and an inability for cryptococci to cross the BBB. brain capillary microvascular endothelial cells",S N Pombejra 2018,2018,1 gene,Na Pombejra-2018-The structure-function analys,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12288,PHI:8476,,no data found,,,,,,MPR1,,MPR1QGA,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,primates,9606,Homo sapiens (related: human),hCMEC/D3 cell line,,,HCMEC/D3 cell,secreted metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30161190,PubMed,10.1371/journal.pone.0203020,PLoS One. 2018 Aug 30;13(8):e0203020,acgelli@ucdavis.edu,"The study identified the prodomain cleavage sites of Mpr1 and demonstrated that when mutated, the prodomain appears to remain attached to the catalytic C-terminus of Mpr1 rendering a nonfunctional Mpr1 protein and an inability for cryptococci to cross the BBB. brain capillary microvascular endothelial cells",S N Pombejra 2018,2018,1 gene,Na Pombejra-2018-The structure-function analys,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12289,PHI:8476,,no data found,,,,,,MPR1,,MPR1QGAA,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,primates,9606,Homo sapiens (related: human),hCMEC/D3 cell line,,,HCMEC/D3 cell,secreted metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30161190,PubMed,10.1371/journal.pone.0203020,PLoS One. 2018 Aug 30;13(8):e0203020,acgelli@ucdavis.edu,"The study identified the prodomain cleavage sites of Mpr1 and demonstrated that when mutated, the prodomain appears to remain attached to the catalytic C-terminus of Mpr1 rendering a nonfunctional Mpr1 protein and an inability for cryptococci to cross the BBB. brain capillary microvascular endothelial cells",S N Pombejra 2018,2018,1 gene,Na Pombejra-2018-The structure-function analys,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12290,PHI:8476,,no data found,,,,,,MPR1,,MPR1ProMut(Myc),,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,primates,9606,Homo sapiens (related: human),hCMEC/D3 cell line,,,HCMEC/D3 cell,secreted metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30161190,PubMed,10.1371/journal.pone.0203020,PLoS One. 2018 Aug 30;13(8):e0203020,acgelli@ucdavis.edu,"The study identified the prodomain cleavage sites of Mpr1 and demonstrated that when mutated, the prodomain appears to remain attached to the catalytic C-terminus of Mpr1 rendering a nonfunctional Mpr1 protein and an inability for cryptococci to cross the BBB. brain capillary microvascular endothelial cells",S N Pombejra 2018,2018,1 gene,Na Pombejra-2018-The structure-function analys,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12291,PHI:8476,,no data found,,,,,,MPR1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,primates,9606,Homo sapiens (related: human),hCMEC/D3 cell line,,,HCMEC/D3 cell,secreted metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30161190,PubMed,10.1371/journal.pone.0203020,PLoS One. 2018 Aug 30;13(8):e0203020,acgelli@ucdavis.edu,"The study identified the prodomain cleavage sites of Mpr1 and demonstrated that when mutated, the prodomain appears to remain attached to the catalytic C-terminus of Mpr1 rendering a nonfunctional Mpr1 protein and an inability for cryptococci to cross the BBB. brain capillary microvascular endothelial cells",S N Pombejra 2018,2018,1 gene,Na Pombejra-2018-The structure-function analys,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12292,PHI:8477,UniProt,Q9KRX4,GenBank,AAF94664,,,N16961,cobB (VC1509),chromosome I,,,,,,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12293,PHI:8478,UniProt,Q9KV59,GenBank,AAF93472,,,N16961,acs (VC0298),chromosome I,,,,,,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,acetyl-CoA synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12294,PHI:8478,UniProt,Q9KV59,GenBank,AAF93472,,,N16961,acs (VC0298),chromosome I,K609R,,,,,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,acetyl-CoA synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12295,PHI:8478,UniProt,Q9KV59,GenBank,AAF93472,,,N16961,acs (VC0298),chromosome I,K609R,,,,PHI:8477,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,acetyl-CoA synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12296,PHI:8477,UniProt,Q9KRX4,GenBank,AAF94664,,,N16961,cobB (VC1509),chromosome I,,,,,PHI:8478,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12297,PHI:8478,UniProt,Q9KV59,GenBank,AAF93472,,,N16961,acs (VC0298),chromosome I,L641A,,,,,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,acetyl-CoA synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12298,PHI:8478,UniProt,Q9KV59,GenBank,AAF93472,,,N16961,acs (VC0298),chromosome I,L641A,,,,PHI:8477,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,acetyl-CoA synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12299,PHI:8477,UniProt,Q9KRX4,GenBank,AAF94664,,,N16961,cobB (VC1509),chromosome I,,,,,PHI:8478,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12300,PHI:8479,UniProt,Q9KM15,GenBank,AAF96476,,,N16961,yfiq (VCA0574),chromosome II,,,,,,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative acetyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12301,PHI:8479,UniProt,Q9KM15,GenBank,AAF96476,,,N16961,yfiq (VCA0574),chromosome II,,,,,PHI:8477,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative acetyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12302,PHI:8477,UniProt,Q9KRX4,GenBank,AAF94664,,,N16961,cobB (VC1509),chromosome I,,,,,PHI:8479,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12303,PHI:8480,UniProt,Q9KQF6,GenBank,AAF95190,,,N16961,acuC (VC2042),chromosome I,,,,,,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12304,PHI:8477,UniProt,Q9KRX4,GenBank,AAF94664,,,N16961,cobB (VC1509),chromosome I,,,,,PHI:8480,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12305,PHI:8480,UniProt,Q9KQF6,GenBank,AAF95190,,,N16961,acuC (VC2042),chromosome I,,,,,PHI:8477,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12306,PHI:8480,UniProt,Q9KQF6,GenBank,AAF95190,,,N16961,acuC (VC2042),chromosome I,,,,,PHI:8479,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12307,PHI:8479,UniProt,Q9KM15,GenBank,AAF96476,,,N16961,yfiq (VCA0574),chromosome II,,,,,PHI:8480,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12308,PHI:8477,UniProt,Q9KRX4,GenBank,AAF94664,,,N16961,cobB (VC1509),chromosome I,,,,,PHI:8480; PHI:8479,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12309,PHI:8480,UniProt,Q9KQF6,GenBank,AAF95190,,,N16961,acuC (VC2042),chromosome I,,,,,PHI:8477; PHI:8479,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12310,PHI:8479,UniProt,Q9KM15,GenBank,AAF96476,,,N16961,yfiq (VCA0574),chromosome II,,,,,PHI:8477; PHI:8480,666,Vibrio cholerae,,SIO,cholera,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,putative deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30143508,PubMed,10.1128/AEM.01113-18,Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e01113-18,apurdy@amherst.edu,It was demonstrated that proteins likely involved in acetylation can modulate the outcome of infection by regulating metabolite exchange between pathogens and their colonized hosts.,K Liimatta 2018,2018,4 genes,Liimatta-2018-A putative acetylation system in,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12311,PHI:8481,UniProt,Q3BW17,GenBank,CAJ22946,,,85-10,hrpX,,,,,,,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,AraC-type transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12312,PHI:8482,UniProt,Q3BS08,GenBank,CAJ24403,,,85-10,XeHypBA1 (XCV2724),,,,,,,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,putative secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12313,PHI:8483,UniProt,Q3BS03,GenBank,CAJ24408,,,85-10,XeHypBA2 (XCV2729),,,,,,,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,putative secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12314,PHI:8484,UniProt,Q3BS04,GenBank,CAJ24407,,,85-10,XeHypAA (XCV2728),,,,,,,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,putative xylosidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12315,PHI:8482,UniProt,Q3BS08,GenBank,CAJ24403,,,85-10,XeHypBA1 (XCV2724),,,,,,PHI:8483; PHI:8484,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,putative secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12316,PHI:8483,UniProt,Q3BS03,GenBank,CAJ24408,,,85-10,XeHypBA2 (XCV2729),,,,,,PHI:8482; PHI:8484,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,putative secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12317,PHI:8484,UniProt,Q3BS04,GenBank,CAJ24407,,,85-10,XeHypAA (XCV2728),,,,,,PHI:8482; PHI:8483,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,putative xylosidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12318,PHI:8483,UniProt,Q3BS03,GenBank,CAJ24408,,,85-10,XeHypBA2 (XCV2729),,,,,,PHI:8484,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,putative secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12319,PHI:8484,UniProt,Q3BS04,GenBank,CAJ24407,,,85-10,XeHypAA (XCV2728),,,,,,PHI:8483,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,putative xylosidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12320,PHI:8481,UniProt,Q3BW17,GenBank,CAJ22946,,,85-10,hrpX,,,,,,,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,AraC-type transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12321,PHI:8482,UniProt,Q3BS08,GenBank,CAJ24403,,,85-10,XeHypBA1 (XCV2724),,,,,,,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,putative secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12322,PHI:8483,UniProt,Q3BS03,GenBank,CAJ24408,,,85-10,XeHypBA2 (XCV2729),,,,,,,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,putative secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12323,PHI:8484,UniProt,Q3BS04,GenBank,CAJ24407,,,85-10,XeHypAA (XCV2728),,,,,,,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,putative xylosidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12324,PHI:8482,UniProt,Q3BS08,GenBank,CAJ24403,,,85-10,XeHypBA1 (XCV2724),,,,,,PHI:8483; PHI:8484,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,putative secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12325,PHI:8483,UniProt,Q3BS03,GenBank,CAJ24408,,,85-10,XeHypBA2 (XCV2729),,,,,,PHI:8482; PHI:8484,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,putative secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12326,PHI:8484,UniProt,Q3BS04,GenBank,CAJ24407,,,85-10,XeHypAA (XCV2728),,,,,,PHI:8482; PHI:8483,456327,Xanthomonas euvesicatoria,,UPB139,bacterial spot (pepper); bacterial spot (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,putative xylosidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30092047,PubMed,10.1371/journal.pone.0201982,PLoS One. 2018 Aug 9;13(8):e0201982,masa@agri.kagoshima-u.ac.jp,"Three single-gene deletion mutants (ΔxehypBA1, ΔxehypBA2, ΔxehypAA) and even a triple-gene deletion mutant (ΔxehypBA1-BA2-AA) remained pathogenic, and had no effect on nonhost resistance.",M Nakamura 2018,2018,4 genes,Nakamura-2018-Functional characterization of u,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12327,PHI:8485,UniProt,Q9KM62,GenBank,AAF96429,,,N16961,clcA,chromosome II,,,,,,666,Vibrio cholerae,,,cholera,rodents,10090,Mus musculus (related: house mouse),,,,gastrointestinal tract,H+/Cl-transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: constitutive expression,,,YVS,30110191,PubMed,10.1080/19490976.2018.1502538,Gut Microbes. 2018 Aug 15:1-7,stefan.schild@uni-graz.at,"Constitutive expression of clcA became detrimental under alkaline conditions, e.g. during colonization of the lower gastrointestinal tract.",F Cakar 2018,2018,1 gene,Cakar-2018-Silence is golden_ gene silencing o,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12328,PHI:8485,UniProt,Q9KM62,GenBank,AAF96429,,,N16961,clcA,chromosome II,,,,,,666,Vibrio cholerae,,,cholera,rodents,10090,Mus musculus (related: house mouse),,,,gastrointestinal tract,H+/Cl-transporter,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30110191,PubMed,10.1080/19490976.2018.1502538,Gut Microbes. 2018 Aug 15:1-7,stefan.schild@uni-graz.at,Silencing of ivr genes seemed to be crucial to achieve full colonization fitness.,F Cakar 2018,2018,1 gene,Cakar-2018-Silence is golden_ gene silencing o,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12329,PHI:8486,,no data found,,,,,,Bmsr1,chromosome 1,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small regulatory RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30173733,PubMed,10.1016/j.vetmic.2018.07.007,Vet Microbiol. 2018 Sep;223:1-8,xuda_official@163.com,"In a mouse model of chronic infection, bmsr1 deletion strain displayed decreased colonization in the spleen while Bmsr1-overexpressed strain showed higher colonization levels than wild type pathogen.",D Xu 2018,2018,1 gene,Xu-2018-A novel small RNA Bmsr1 enhances virul,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12330,PHI:8486,,no data found,,,,,,Bmsr1,chromosome 1,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,small regulatory RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30173733,PubMed,10.1016/j.vetmic.2018.07.007,Vet Microbiol. 2018 Sep;223:1-8,xuda_official@163.com,"In a mouse model of chronic infection, bmsr1 deletion strain displayed decreased colonization in the spleen while Bmsr1-overexpressed strain showed higher colonization levels than wild type pathogen.",D Xu 2018,2018,1 gene,Xu-2018-A novel small RNA Bmsr1 enhances virul,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12331,PHI:8487,UniProt,P28307,GenBank,AAA23616,,,K-12,csgA,,,,,,,562,Escherichia coli,,MS7163,pyelonephritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bladder,Curli major subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30131362,PubMed,10.1128/mBio.01462-18,MBio. 2018 Aug 21;9(4). pii: e01462-18,m.schembri@uq.edu.au,Curli enhanced colonization of the mouse urinary tract.,N T K Nhu 2018,2018,3 genes,Nhu-2018-Discovery of New Genes Involved in Cu,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12332,PHI:8488,UniProt,P0AG16,GenBank,CAA30971,,,K-12,purF,,,,,,,562,Escherichia coli,,MS7163,pyelonephritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bladder,amidophosphoribosyl transferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30131362,PubMed,10.1128/mBio.01462-18,MBio. 2018 Aug 21;9(4). pii: e01462-18,m.schembri@uq.edu.au,Mutation of purF (the first gene in the purine biosynthesis pathway) and rcpA also led to attenuated colonization of the mouse bladder.,N T K Nhu 2018,2018,3 genes,Nhu-2018-Discovery of New Genes Involved in Cu,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12333,PHI:8489,UniProt,A0A024KPG5,GenBank,CDU33739,,,D6-113.11,rcpA,,,,,,,562,Escherichia coli,,MS7163,pyelonephritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bladder,repressor of curli production,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30131362,PubMed,10.1128/mBio.01462-18,MBio. 2018 Aug 21;9(4). pii: e01462-18,m.schembri@uq.edu.au,Mutation of purF (the first gene in the purine biosynthesis pathway) and rcpA also led to attenuated colonization of the mouse bladder.,N T K Nhu 2018,2018,3 genes,Nhu-2018-Discovery of New Genes Involved in Cu,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12334,PHI:8488,UniProt,P0AG16,GenBank,CAA30971,,,K-12,purF,,,,,,,562,Escherichia coli,,MS7163,pyelonephritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,amidophosphoribosyl transferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30131362,PubMed,10.1128/mBio.01462-18,MBio. 2018 Aug 21;9(4). pii: e01462-18,m.schembri@uq.edu.au,Mutation of purF (the first gene in the purine biosynthesis pathway) and rcpA also led to attenuated colonization of the mouse bladder.,N T K Nhu 2018,2018,3 genes,Nhu-2018-Discovery of New Genes Involved in Cu,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12335,PHI:8489,UniProt,A0A024KPG5,GenBank,CDU33739,,,D6-113.11,rcpA,,,,,,,562,Escherichia coli,,MS7163,pyelonephritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,repressor of curli production,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30131362,PubMed,10.1128/mBio.01462-18,MBio. 2018 Aug 21;9(4). pii: e01462-18,m.schembri@uq.edu.au,Mutation of purF (the first gene in the purine biosynthesis pathway) and rcpA also led to attenuated colonization of the mouse bladder.,N T K Nhu 2018,2018,3 genes,Nhu-2018-Discovery of New Genes Involved in Cu,BATCH_086B,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12336,PHI:8490,UniProt,G2X8L4,GenBank,EGY15301,,,VdLs.17,VdPEL1,chromosome 8,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30271415,PubMed,10.3389/fpls.2018.01271,Front Plant Sci. 2018 Sep 13;9:1271,qiudewen@caas.cn,"The mutant VdPEL1rec lacking the enzymatic activity lacked functions to induce both cell death and plant resistance, implying that the enzymatic activity was necessary.",Y Yang 2018,2018,1 gene,Yang-2018-A Verticillium dahliae Pectate Lyase,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12337,PHI:8490,UniProt,G2X8L4,GenBank,EGY15301,,,VdLs.17,VdPEL1,chromosome 8,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30271415,PubMed,10.3389/fpls.2018.01271,Front Plant Sci. 2018 Sep 13;9:1271,qiudewen@caas.cn,"The mutant VdPEL1rec lacking the enzymatic activity lacked functions to induce both cell death and plant resistance, implying that the enzymatic activity was necessary.",Y Yang 2018,2018,1 gene,Yang-2018-A Verticillium dahliae Pectate Lyase,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12338,PHI:8490,UniProt,G2X8L4,GenBank,EGY15301,,,VdLs.17,VdPEL1,chromosome 8,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,pectate lyase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30271415,PubMed,10.3389/fpls.2018.01271,Front Plant Sci. 2018 Sep 13;9:1271,qiudewen@caas.cn,"The mutant VdPEL1rec lacking the enzymatic activity lacked functions to induce both cell death and plant resistance, implying that the enzymatic activity was necessary.",Y Yang 2018,2018,1 gene,Yang-2018-A Verticillium dahliae Pectate Lyase,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12339,PHI:8490,UniProt,G2X8L4,GenBank,EGY15301,,,VdLs.17,VdPEL1,chromosome 8,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,pectate lyase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,30271415,PubMed,10.3389/fpls.2018.01271,Front Plant Sci. 2018 Sep 13;9:1271,qiudewen@caas.cn,"The mutant VdPEL1rec lacking the enzymatic activity lacked functions to induce both cell death and plant resistance, implying that the enzymatic activity was necessary.",Y Yang 2018,2018,1 gene,Yang-2018-A Verticillium dahliae Pectate Lyase,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12340,PHI:8490,UniProt,G2X8L4,GenBank,EGY15301,,,VdLs.17,VdPEL1,chromosome 8,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,pectate lyase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,30271415,PubMed,10.3389/fpls.2018.01271,Front Plant Sci. 2018 Sep 13;9:1271,qiudewen@caas.cn,"The mutant VdPEL1rec lacking the enzymatic activity lacked functions to induce both cell death and plant resistance, implying that the enzymatic activity was necessary.",Y Yang 2018,2018,1 gene,Yang-2018-A Verticillium dahliae Pectate Lyase,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12341,PHI:8490,UniProt,G2X8L4,GenBank,EGY15301,,,VdLs.17,VdPEL1,chromosome 8,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,pectate lyase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,30271415,PubMed,10.3389/fpls.2018.01271,Front Plant Sci. 2018 Sep 13;9:1271,qiudewen@caas.cn,"The mutant VdPEL1rec lacking the enzymatic activity lacked functions to induce both cell death and plant resistance, implying that the enzymatic activity was necessary.",Y Yang 2018,2018,1 gene,Yang-2018-A Verticillium dahliae Pectate Lyase,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12342,PHI:8490,UniProt,G2X8L4,GenBank,EGY15301,,,VdLs.17,VdPEL1,chromosome 8,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3847,Glycine max (related: soybean),,,,leaf,pectate lyase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,30271415,PubMed,10.3389/fpls.2018.01271,Front Plant Sci. 2018 Sep 13;9:1271,qiudewen@caas.cn,"The mutant VdPEL1rec lacking the enzymatic activity lacked functions to induce both cell death and plant resistance, implying that the enzymatic activity was necessary.",Y Yang 2018,2018,1 gene,Yang-2018-A Verticillium dahliae Pectate Lyase,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12343,PHI:8491,UniProt,A0A2P1C6A6,GenBank,AVJ35632,,,,Pst_8713,,,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30254653,PubMed,10.3389/fpls.2018.01294,Front Plant Sci. 2018 Sep 11;9:1294,wangxiaojie@nwsuaf.edu.cn,Effector-triggered immunity (ETI) induced by an avirulent Pst isolate was weakened when we overexpressed Pst_8713 in wheat leaves which accompanied by reduction of reactive oxygen species (ROS) accumulation and hypersensitive response (HR).,M Zhao 2018,2018,1 gene,Zhao-2018-Candidate Effector Pst_8713 Impairs,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12344,PHI:8491,UniProt,A0A2P1C6A6,GenBank,AVJ35632,,,,Pst_8713,,,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30254653,PubMed,10.3389/fpls.2018.01294,Front Plant Sci. 2018 Sep 11;9:1294,wangxiaojie@nwsuaf.edu.cn,Effector-triggered immunity (ETI) induced by an avirulent Pst isolate was weakened when we overexpressed Pst_8713 in wheat leaves which accompanied by reduction of reactive oxygen species (ROS) accumulation and hypersensitive response (HR).,M Zhao 2018,2018,1 gene,Zhao-2018-Candidate Effector Pst_8713 Impairs,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12345,PHI:8491,UniProt,A0A2P1C6A6,GenBank,AVJ35632,,,,Pst_8713,,,,,,,27350,Puccinia striiformis,1240226,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30254653,PubMed,10.3389/fpls.2018.01294,Front Plant Sci. 2018 Sep 11;9:1294,wangxiaojie@nwsuaf.edu.cn,The host induced gene silencing (HIGS) experiment showed that knockdown of Pst_8713 weakened the virulence of Pst by producing fewer uredinia.,M Zhao 2018,2018,1 gene,Zhao-2018-Candidate Effector Pst_8713 Impairs,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12346,PHI:8492,UniProt,Q05938,GenBank,BAA89504,,,BE98-2062,ToxR,,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,virulence regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30234024,PubMed,10.3389/fcimb.2018.00291,Front Cell Infect Microbiol. 2018 Sep 5;8:291,huxinx@ujs.edu.cn,"ToxR inhibited the cytotoxicity, but it activated mouse lethality, hemolytic activity and enterotoxicity of V.parahaemolyticus.",Y Zhang 2018,2018,1 gene,Zhang-2018-Autoregulation of ToxR and Its Regu,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12347,PHI:8492,UniProt,Q05938,GenBank,BAA89504,,,BE98-2062,ToxR,,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,ileum,virulence regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30234024,PubMed,10.3389/fcimb.2018.00291,Front Cell Infect Microbiol. 2018 Sep 5;8:291,huxinx@ujs.edu.cn,"ToxR inhibited the cytotoxicity, but it activated mouse lethality, hemolytic activity and enterotoxicity of V.parahaemolyticus. ileal intestinal tissue",Y Zhang 2018,2018,1 gene,Zhang-2018-Autoregulation of ToxR and Its Regu,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12348,PHI:8492,UniProt,Q05938,GenBank,BAA89504,,,BE98-2062,ToxR,,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,erythrocyte,virulence regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30234024,PubMed,10.3389/fcimb.2018.00291,Front Cell Infect Microbiol. 2018 Sep 5;8:291,huxinx@ujs.edu.cn,"ToxR inhibited the cytotoxicity, but it activated mouse lethality, hemolytic activity and enterotoxicity of V.parahaemolyticus.",Y Zhang 2018,2018,1 gene,Zhang-2018-Autoregulation of ToxR and Its Regu,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12349,PHI:8492,UniProt,Q05938,GenBank,BAA89504,,,BE98-2062,ToxR,,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,virulence regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30234024,PubMed,10.3389/fcimb.2018.00291,Front Cell Infect Microbiol. 2018 Sep 5;8:291,huxinx@ujs.edu.cn,"ToxR inhibited the cytotoxicity, but it activated mouse lethality, hemolytic activity and enterotoxicity of V.parahaemolyticus.",Y Zhang 2018,2018,1 gene,Zhang-2018-Autoregulation of ToxR and Its Regu,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12350,PHI:8493,UniProt,Q1J5K9,GenBank,ABF38377,,,MGAS10750,RocA,,contains a 1-bp insertion in rocA,,,,,1314,Streptococcus pyogenes,,MGAS2096,infection,primates,9606,Homo sapiens (related: human),,,,blood,encodes an accessory protein to the virulence-regulating two-component system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30333182,PubMed,10.1128/mSphere.00519-18,mSphere. 2018 Oct 17;3(5). pii: e00519-18,psumby@med.unr.edu,"Natural mutation of rocA in strain MGAS2096 reduced, rather than enhanced, survival in blood ex vivo and complementation of functional rocA increased the ability of this strain to survive.",P Sarkar 2018,2018,1 gene,Sarkar-2018-Phenotypic Variation in the Group,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12351,PHI:8494,UniProt,Q4WZL4,GenBank,EAL93951,,,Af293,pld,chromosome 2,,,,,,746128,Aspergillus fumigatus,,Af293,invasive pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),HEK-293 cell line,,,epithelial cell,phospholipase D,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30286953,PubMed,10.1016/j.bbrc.2018.09.157,Biochem Biophys Res Commun. 2018 Nov 2;505(3):651-656,kkhuo@fudan.edu.cn,Overexpressed PLD strongly inhibited cell proliferation.,S Yu 2018,2018,1 gene,Yu-2018-Aspergillus fumigatus phospholipase D,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12352,PHI:8495,,no data found,,,,,,BASI74,,,,,,,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,virulence-related sRNA,,,,reduced virulence,,,,,,,,,,no,"H2O2; 2,2-dipyridyl","H2O2: CHEBI:16240; 2,2-dipyridyl: CHEBI:30351",,,,,altered gene expression / gene regulation: overexpression,,,YVS,30271397,PubMed,10.3389/fmicb.2018.02173,Front Microbiol. 2018 Sep 13;9:2173,wuqm@cau.edu.cn,Over-expression of the sRNA BASI74 significantly reduced Brucella virulence in the macrophage infection model.,H Dong 2018,2018,1 gene,"Dong-2018-BASI74, a Virulence-Related sRNA in",BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12353,PHI:8495,,no data found,,,,,,BASI74,,,,,,,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,virulence-related sRNA,,,,unaffected pathogenicity,,,,,,,,,,no,"H2O2; 2,2-dipyridyl","H2O2: CHEBI:16240; 2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30271397,PubMed,10.3389/fmicb.2018.02173,Front Microbiol. 2018 Sep 13;9:2173,wuqm@cau.edu.cn,No significant difference was observed in the splenic CFUs between 2308-ΔBASI74 and wild type 2308-infected groups.,H Dong 2018,2018,1 gene,"Dong-2018-BASI74, a Virulence-Related sRNA in",BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12354,PHI:8496,UniProt,C4YHF1,GenBank,EEQ45183,,,WO-1,MGM1,chromosome 4,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,dynamin-related GTPase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30240789,PubMed,10.1016/j.fgb.2018.09.006,Fungal Genet Biol. 2018 Sep 18;120:42-52,nklimingchun@163.com,The deletion of MGM1 led to mitochondrial fragmentation and mtDNA loss and activated the checkpoint pathway to arrest the cell cycle in G1 phase.,C Liang,2018,1 gene,Liang-2018-Mgm1 is required for maintenance of,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12355,PHI:8496,UniProt,C4YHF1,GenBank,EEQ45183,,,WO-1,MGM1,chromosome 4,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,dynamin-related GTPase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30240789,PubMed,10.1016/j.fgb.2018.09.006,Fungal Genet Biol. 2018 Sep 18;120:42-52,nklimingchun@163.com,The deletion of MGM1 led to mitochondrial fragmentation and mtDNA loss and activated the checkpoint pathway to arrest the cell cycle in G1 phase.,C Liang,2018,1 gene,Liang-2018-Mgm1 is required for maintenance of,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12356,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,hemolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death. Table1 and Fig2",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12357,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltaduf1,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,MARTX cytotoxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death. Table1 and Fig2",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12358,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,hemolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death. Table1 and Fig2",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12359,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltarid,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,MARTX cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death. Table1 and Fig2",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12360,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,hemolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death. Table1 and Fig2",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12361,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltaabh,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,MARTX cytotoxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death. Table1 and Fig2",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12362,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,hemolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death. Table1 and Fig2",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12363,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltamcf,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,MARTX cytotoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death. Table1 and Fig2",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12364,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,hemolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death. Table1 and Fig2",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12365,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltarrsp,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,MARTX cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death. Table1 and Fig2",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12366,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,hemolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death.",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12367,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,hemolysin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death.",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12368,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,intestine; liver; spleen,MARTX cytotoxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"Removal of rid or rrsp significantly reduced V. vulnificus virulence potential, while deletion of duf1 or abh accelerated time to death.",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12369,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hemolysin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12370,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltartxA1,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,MARTX cytotoxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12371,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hemolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12372,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltaduf1,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,MARTX cytotoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12373,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hemolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12374,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltarid,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,MARTX cytotoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12375,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hemolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12376,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltaabh,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,MARTX cytotoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12377,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hemolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12378,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltamcf,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,MARTX cytotoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12379,PHI:8497,UniProt,P19247,GenBank,AAA03245,,,,vvhA,,,,,,PHI:8498,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hemolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12380,PHI:8498,UniProt,F1CLH1,GenBank,ADX36382,,,,rtxA1,,deltarrsp,,,,PHI:8497,672,Vibrio vulnificus,,CMCP6 ΔvvhA Rifr,vibriosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,MARTX cytotoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30289477,PubMed,10.1093/infdis/jiy590,J Infect Dis. 2018 Oct 5,k-satchell@northwestern.edu,"The effector domain region was required for V. vulnificus to inhibit phagocytosis by J774 macrophages, but no single effector domain was required. Fig4",H E Gavin 2018,2018,7 genes,Gavin-2018-RRSP and RID Effector Domains Domin,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12381,PHI:8504,UniProt,D5AHT5,GenBank,ADE31400,,,GZ1,Rex,,,,,,,1307,Streptococcus suis,,SS2-1,septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,redox-sensing regulator,,,"glycolysis/gluconeogenesis, pentose phosphate pathway, citrate cycle (TCA cycle)",reduced virulence,,,,,,,,,,no,H2O2; HCl,H2O2: CHEBI:16240; HCl: CHEBI:17883,,,,,gene deletion: full; gene complementation,,,YVS,30280091,PubMed,10.3389/fcimb.2018.00317,Front Cell Infect Microbiol. 2018 Sep 18;8:317,kwh2003@263.net,Rex-knockout mutant strain Δrex exhibited impaired growth in medium with hydrogen peroxide or a low pH compared with the wildtype strain SS2-1.,H Zhu 2018,2018,1 gene,Zhu-2018-The Redox-Sensing Regulator Rex Contr,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12382,PHI:8504,UniProt,D5AHT5,GenBank,ADE31400,,,GZ1,Rex,,,,,,,1307,Streptococcus suis,,SS2-1,septicemia; meningitis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,redox-sensing regulator,,,"glycolysis/gluconeogenesis, pentose phosphate pathway, citrate cycle (TCA cycle)",reduced virulence,,,,,,,,,,no,H2O2; HCl,H2O2: CHEBI:16240; HCl: CHEBI:17883,,,,,gene deletion: full; gene complementation,,,YVS,30280091,PubMed,10.3389/fcimb.2018.00317,Front Cell Infect Microbiol. 2018 Sep 18;8:317,kwh2003@263.net,Rex-knockout mutant strain Δrex exhibited impaired growth in medium with hydrogen peroxide or a low pH compared with the wildtype strain SS2-1.,H Zhu 2018,2018,1 gene,Zhu-2018-The Redox-Sensing Regulator Rex Contr,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12383,PHI:8504,UniProt,D5AHT5,GenBank,ADE31400,,,GZ1,Rex,,,,,,,1307,Streptococcus suis,,SS2-1,septicemia; meningitis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,redox-sensing regulator,,,"glycolysis/gluconeogenesis, pentose phosphate pathway, citrate cycle (TCA cycle)",unaffected pathogenicity,,,,,,,,,,no,H2O2; HCl,H2O2: CHEBI:16240; HCl: CHEBI:17883,,,,,gene deletion: full; gene complementation,,,YVS,30280091,PubMed,10.3389/fcimb.2018.00317,Front Cell Infect Microbiol. 2018 Sep 18;8:317,kwh2003@263.net,Rex-knockout mutant strain Δrex exhibited impaired growth in medium with hydrogen peroxide or a low pH compared with the wildtype strain SS2-1.,H Zhu 2018,2018,1 gene,Zhu-2018-The Redox-Sensing Regulator Rex Contr,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12384,PHI:8504,UniProt,D5AHT5,GenBank,ADE31400,,,GZ1,Rex,,,,,,,1307,Streptococcus suis,,SS2-1,septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,redox-sensing regulator,,,"glycolysis/gluconeogenesis, pentose phosphate pathway, citrate cycle (TCA cycle)",reduced virulence,,,,,,,,,,no,H2O2; HCl,H2O2: CHEBI:16240; HCl: CHEBI:17883,,,,,gene deletion: full; gene complementation,,,YVS,30280091,PubMed,10.3389/fcimb.2018.00317,Front Cell Infect Microbiol. 2018 Sep 18;8:317,kwh2003@263.net,Rex-knockout mutant strain Δrex exhibited impaired growth in medium with hydrogen peroxide or a low pH compared with the wildtype strain SS2-1.,H Zhu 2018,2018,1 gene,Zhu-2018-The Redox-Sensing Regulator Rex Contr,BATCH_087A,2018-10-01,MC,,,,,,,,,,,,,
,,Record 12385,PHI:5775,UniProt,I1S474,Ensembl Genomes,FGRAMPH1_01G00023,,,PH-1,ScOrtholog_PIG2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,,,,,reduced virulence,,,,,,increased,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12386,PHI:5694,UniProt,I1RAA8,Ensembl Genomes,FGRAMPH1_01G01131,,,PH-1,ScOrtholog_PTC7,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12387,PHI:5695,UniProt,I1RAJ9,Ensembl Genomes,FGRAMPH1_01G01355,,,PH-1,ScOrtholog_PHO11,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,increased,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12388,PHI:5696,UniProt,I1RAL2,Ensembl Genomes,FGRAMPH1_01G01385,,,PH-1,ScOrtholog_CDC14,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,"role in ribosome biogenesis (Fig 8e); mutant contains multiple nuclei in single conidial cells (Fig S3); complements Sc cdc14 mutant. Mutant forms some interconnected conida (Fig 7b), Gene is likely associated with cell division. Yeast2Hybrid assays identified FgTfc7 (FGSG_09985) as interacting protein that is infolved in RNA polymerase III transcription of 5S rRNA.",Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12389,PHI:5697,UniProt,I1RAN3,Ensembl Genomes,FGRAMPH1_01G01439,,,PH-1,ScOrtholog_MIH1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12390,PHI:5698,UniProt,I1RAZ1,Ensembl Genomes,FGRAMPH1_01G01733,,,PH-1,ScOrtholog_SAC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12391,PHI:5699,UniProt,I1RBD6,Ensembl Genomes,FGRAMPH1_01G02133,,,PH-1,ScOrtholog_PPZ1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,serine/threonine-protein phosphatase (EC 3.1.3.16),,,,reduced virulence,,,,,,wild type,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12392,PHI:5700,UniProt,Q4IPC8,Ensembl Genomes,FgramPH1_01G02345,,,PH-1,ScOrtholog_SSU72,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12393,PHI:5701,UniProt,I1RBW6,Ensembl Genomes,FGRAMPH1_01G02643,,,PH-1,ScOrtholog_ISC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12394,PHI:5702,UniProt,V6QW25,Ensembl Genomes,FGRAMPH1_01G03073,,,PH-1,ScOrtholog_INP52,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12395,PHI:5703,UniProt,A0A1C3YIA8,Ensembl Genomes,FGRAMPH1_01G03379,,,PH-1,ScOrtholog_CDC55,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,protein phosphatase PP2A regulatory subunit B,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12396,PHI:5704,UniProt,I1RCY0,Ensembl Genomes,FGRAMPH1_01G03595,,,PH-1,ScOrtholog_SIT4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,serine/threonine-protein phosphatase (EC 3.1.3.16),,,,reduced virulence,,,,,,wild type,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12397,PHI:5705,UniProt,I1RD38,Ensembl Genomes,FGRAMPH1_01G03731,,,PH-1,ScOrtholog_PSR2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,increased,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,reduced hyphal branches,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12398,PHI:5706,UniProt,I1RDH5,Ensembl Genomes,FGRAMPH1_01G04065,,,PH-1,ScOrtholog_SWI14,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12399,PHI:5707,UniProt,I1RE45,Ensembl Genomes,FGRAMPH1_01G04633,,,PH-1,ScOrtholog_PAP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12400,PHI:5708,UniProt,I1REF5,Ensembl Genomes,FGRAMPH1_01G04933,,,PH-1,ScOrtholog_CCR4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12401,PHI:5709,UniProt,I1REK1,Ensembl Genomes,FGRAMPH1_01G05041,,,PH-1,ScOrtholog_INP53,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12402,PHI:5710,UniProt,A0A1C3YIL6,Ensembl Genomes,FGRAMPH1_01G05981,,,PH-1,ScOrtholog_UTR4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12403,PHI:5711,UniProt,I1RGL2,Ensembl Genomes,FGRAMPH1_01G11531,,,PH-1,FGSG_02883,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12404,PHI:5712,UniProt,I1RH75,Ensembl Genomes,FGRAMPH1_01G12109,,,PH-1,ScOrtholog_DPP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12405,PHI:5713,UniProt,I1RHS0,Ensembl Genomes,FGRAMPH1_01G12627,,,PH-1,ScOrtholog_ARC15,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,negative regulator of Gpmk1 mitogen-activated protein kinase signaling pathway,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12406,PHI:5714,UniProt,I1RHV0,Ensembl Genomes,FGRAMPH1_01G12701,,,PH-1,ScOrtholog_ISC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12407,PHI:5715,UniProt,I1RHV1,Ensembl Genomes,FGRAMPH1_01G12703,,,PH-1,ScOrtholog_PHO12,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,increased,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12408,PHI:5716,UniProt,I1RHY5,Ensembl Genomes,FGRAMPH1_01G12793,,,PH-1,ScOrtholog_PHO11,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12409,PHI:5717,UniProt,I1RJ27,Ensembl Genomes,FGRAMPH1_01G13801,,,PH-1,FGSG_03826,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12410,PHI:5718,UniProt,I1RJG6,Ensembl Genomes,FGRAMPH1_01G14187,,,PH-1,ScOrtholog_TOS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12411,PHI:5719,UniProt,I1RJK3,Ensembl Genomes,FGRAMPH1_01G14285,,,PH-1,ScOrtholog_PTC5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12412,PHI:5720,UniProt,I1RJS9,Ensembl Genomes,FGRAMPH1_01G14517,,,PH-1,ScOrtholog_PTC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12413,PHI:5721,UniProt,A0A1C3YN32,Ensembl Genomes,FGRAMPH1_01G14613,,,PH-1,ScOrtholog_PHO8,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,alkaline phosphatase (EC 3.1.3.1),,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12414,PHI:5722,UniProt,I1RK86,Ensembl Genomes,FGRAMPH1_01G14909,,,PH-1,ScOrtholog_FIG4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12415,PHI:5723,UniProt,I1RKA0,Ensembl Genomes,FGRAMPH1_01G14947,,,PH-1,ScOrtholog_PPS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,increased,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12416,PHI:5724,UniProt,I1RM09,Ensembl Genomes,FGRAMPH1_01G16797,,,PH-1,ScOrtholog_TEP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12417,PHI:5725,UniProt,I1RM12,Ensembl Genomes,FGRAMPH1_01G16809,,,PH-1,ScOrtholog_MDP-1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12418,PHI:5726,UniProt,I1RM94,Ensembl Genomes,FGRAMPH1_01G17047,,,PH-1,ScOrtholog_VIP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (EC 2.7.4.21) (EC 2.7.4.24),,,,reduced virulence,,,,,,increased,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12419,PHI:5727,UniProt,I1RMH2,Ensembl Genomes,FGRAMPH1_01G17251,,,PH-1,ScOrtholog_PTC6,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12420,PHI:5728,UniProt,I1RML4,Ensembl Genomes,FGRAMPH1_01G17357,,,PH-1,ScOrtholog_PTC5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12421,PHI:5729,UniProt,I1RMT4,Ensembl Genomes,FGRAMPH1_01G17523,,,PH-1,ScOrtholog_PPG1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,serine/threonine-protein phosphatase (EC 3.1.3.16),,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12422,PHI:5730,UniProt,I1RN66,Ensembl Genomes,FGRAMPH1_01G17901,,,PH-1,ScOrtholog_YMR1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12423,PHI:5731,UniProt,I1RN77,Ensembl Genomes,FGRAMPH1_01G17925,,,PH-1,ScOrtholog_YLR157W-E,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12424,PHI:5732,UniProt,I1RNM8,Ensembl Genomes,FGRAMPH1_01G18327,,,PH-1,ScOrtholog_PTC7,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12425,PHI:5733,UniProt,A0A0E0SKE0,Ensembl Genomes,FGRAMPH1_01G18539,,,PH-1,FGSG_05697,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12426,PHI:5734,UniProt,A0A098DXK5,Ensembl Genomes,FGRAMPH1_01G19013,,,PH-1,ScOrtholog_INP53,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,increased,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12427,PHI:5735,UniProt,A0A0E0SNM6,Ensembl Genomes,FGRAMPH1_01G19019,,,PH-1,ScOrtholog_RTS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit,,,,reduced virulence,,,,,,reduced,,reduced,,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,reduced number of hyphal branches,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12428,PHI:5736,UniProt,I1RPQ2,Ensembl Genomes,FGRAMPH1_01G19321,,,PH-1,ScOrtholog_LCB3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12429,PHI:5737,UniProt,A0A0E0SIE1,Ensembl Genomes,FGRAMPH1_01G19491,,,PH-1,ScOrtholog_CNA1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,serine/threonine-protein phosphatase (EC 3.1.3.16),,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12430,PHI:5738,UniProt,I1RPY2,Ensembl Genomes,FGRAMPH1_01G19515,,,PH-1,ScOrtholog_YDR433W,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12431,PHI:5739,UniProt,I1RQF5,Ensembl Genomes,FGRAMPH1_01G19975,,,PH-1,ScOrtholog_PTP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12432,PHI:5740,UniProt,A0A1C3YKI8,Ensembl Genomes,FGRAMPH1_01G22431,,,PH-1,ScOrtholog_PIG2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,increased,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12433,PHI:5741,UniProt,I1RR94,Ensembl Genomes,FGRAMPH1_01G22711,,,PH-1,ScOrtholog_YKL153W,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12434,PHI:5742,UniProt,I1RRJ3,Ensembl Genomes,FGRAMPH1_01G22995,,,PH-1,ScOrtholog_PHO13,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,4-nitrophenylphosphatase (PNPPase) (EC 3.1.3.41),,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12435,PHI:5743,UniProt,I1RS64,Ensembl Genomes,FGRAMPH1_01G23657,,,PH-1,ScOrtholog_SDP2/MSG5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12436,PHI:5744,UniProt,V6RN16,Ensembl Genomes,FGRAMPH1_01G23949,,,PH-1,ScOrtholog_RHR2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12437,PHI:5745,UniProt,A0A1C3YL99,Ensembl Genomes,FGRAMPH1_01G24303,,,PH-1,ScOrtholog_GLC7,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,serine/threonine-protein phosphatase (EC 3.1.3.16),,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12438,PHI:5746,UniProt,I1RT14,Ensembl Genomes,FGRAMPH1_01G24473,,,PH-1,ScOrtholog_PHS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.134),,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12439,PHI:5747,UniProt,I1RT76,Ensembl Genomes,FGRAMPH1_01G24669,,,PH-1,ScOrtholog_CNB1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12440,PHI:5748,UniProt,I1RT94,Ensembl Genomes,FGRAMPH1_01G24713,,,PH-1,ScOrtholog_PPT1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,serine/threonine-protein phosphatase (EC 3.1.3.16),,,,unaffected pathogenicity,,,,,,wild type,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12441,PHI:5749,UniProt,I1RTF8,Ensembl Genomes,FGRAMPH1_01G24877,,,PH-1,ScOrtholog_MIF2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12442,PHI:5750,UniProt,I1RU06,Ensembl Genomes,FGRAMPH1_01G25367,,,PH-1,ScOrtholog_GIC1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12443,PHI:5751,UniProt,I1RU98,Ensembl Genomes,FGRAMPH1_01G25655,,,PH-1,ScOrtholog_DIA3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12444,PHI:5752,UniProt,I1RUG0,Ensembl Genomes,FGRAMPH1_01G25821,,,PH-1,ScOrtholog_FCP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12445,PHI:5753,UniProt,I1RUM7,Ensembl Genomes,FGRAMPH1_01G25999,,,PH-1,FgTPS2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,increased number of hyphal branches/; encodes trehalose 6-phosphate phophatase involved in the biosynthesis of trehalose,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12446,PHI:5754,UniProt,I1RUN3,Ensembl Genomes,FGRAMPH1_01G26017,,,PH-1,ScOrtholog_NGL3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,increased DON production but defects in plant infection,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12447,PHI:5755,UniProt,I1RW69,Ensembl Genomes,FGRAMPH1_01G10185,,,PH-1,ScOrtholog_SER2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12448,PHI:5756,UniProt,I1RWQ1,Ensembl Genomes,FGRAMPH1_01G10679,,,PH-1,ScOrtholog_INP53,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12449,PHI:5757,UniProt,A0A1C3YML3,Ensembl Genomes,FGRAMPH1_01G11095,,,PH-1,ScOrtholog_APN2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12450,PHI:5758,UniProt,Q4I099,Ensembl Genomes,FGRAMPH1_01G27271,,,PH-1,ScOrtholog_TIM50,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12451,PHI:5759,UniProt,I1RYL8,Ensembl Genomes,FGRAMPH1_01G26995,,,PH-1,ScOrtholog_MSS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,increased,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12452,PHI:5760,UniProt,I1RYS3,Ensembl Genomes,FGRAMPH1_01G26863,,,PH-1,ScOrtholog_MET22,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,"grows on MM amended with 1 mM Met, but not 1mM Asp; defective in the utilization of sulfate and sulfite.",Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12453,PHI:5761,UniProt,I1RZ02,Ensembl Genomes,FGRAMPH1_01G26657,,,PH-1,ScOrtholog_PPH3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,serine/threonine-protein phosphatase (EC 3.1.3.16),,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12454,PHI:5762,UniProt,I1RZH4,Ensembl Genomes,FGRAMPH1_01G26211,,,PH-1,ScOrtholog_PPH21,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,serine/threonine-protein phosphatase (EC 3.1.3.16),,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12455,PHI:5763,UniProt,I1S000,Ensembl Genomes,FGRAMPH1_01G07073,,,PH-1,ScOrtholog_PGM1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,increased,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12456,PHI:5764,UniProt,I1S0K9,Ensembl Genomes,FGRAMPH1_01G07619,,,PH-1,ScOrtholog_PTC3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,increased,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12457,PHI:5765,UniProt,I1S0R5,Ensembl Genomes,FGRAMPH1_01G07773,,,PH-1,ScOrtholog_NEM1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,deletion mutant grows better on MM than on PDA,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12458,PHI:5766,UniProt,I1S0S5,Ensembl Genomes,FGRAMPH1_01G07793,,,PH-1,ScOrtholog_LTP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12459,PHI:5767,UniProt,I1S183,Ensembl Genomes,FGRAMPH1_01G08209,,,PH-1,ScOrtholog_TPP1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12460,PHI:5768,UniProt,I1S1B6,Ensembl Genomes,FGRAMPH1_01G08303,,,PH-1,ScOrtholog_YVH1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,loss of pathogenicity,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,unable to penetrate cellophane membrane; maybe essential for penetrations.,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12461,PHI:5769,UniProt,A0A1C3YIW2,Ensembl Genomes,FGRAMPH1_0G03923,,,PH-1,ScOrtholog_PTP3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12462,PHI:5770,UniProt,I1S5C4,Ensembl Genomes,FGRAMPH1_01G04747,,,PH-1,ScOrtholog_PHO5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12463,PHI:5771,UniProt,A0A098E428,Ensembl Genomes,FGRAMPH1_01G16551,,,PH-1,ScOrtholog_PHS1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.134),,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12464,PHI:5772,UniProt,A0A1C3YKG4,Ensembl Genomes,FGRAMPH1_01G19531,,,PH-1,ScOrtholog_GEP4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,negative regulator of HOG mitogen-activated protein kinase signaling pathway; mutant shows increased tolerance to osmotic stress,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12465,PHI:5773,UniProt,I1S9T8,Ensembl Genomes,FGRAMPH1_01G26577,,,PH-1,ScOrtholog_YNL010W,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12466,PHI:5774,UniProt,I1SAX0,Ensembl Genomes,FGRAMPH1_01G21619,,,PH-1,ScOrtholog_RPL15A,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower,uncharacterized protein,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,na,carbendazim: CHEBI:3392,,,,,gene deletion: full,,MU,MU; AS,25758923,PubMed,10.1111/nph.13374,"New Phytol. 207, 119-134,",zhma@zju.edu.cn,,Y Yu,2015,82,na,na,2019-05-01,RRes,,,,,,,,,,,,,
,,Record 12467,PHI:8505,UniProt,Q7CHU5,GenBank,CAL20379,,,CO92,BfvR (YPO1737),,,,,,,632,Yersinia pestis,229193,biovar Microtus strain 91001,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),,,,,AraC-family transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30333962,PubMed,10.3389/fcimb.2018.00347,Front Cell Infect Microbiol. 2018 Oct 2;8:347,dongshengzhou1977@gmail.com,Modulation of biofilm and virulence-related genes by BfvR led to increased biofilm formation and reduced virulence of Y. pestis biovar Microtus.,H Fang 2018,2018,2 genes,"Fang-2018-BfvR, an AraC-Family Regulator, Cont",BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12468,PHI:8505,UniProt,Q7CHU5,GenBank,CAL20379,,,CO92,BfvR (YPO1737),,,,,,,632,Yersinia pestis,229193,biovar Microtus strain 91001,pneumonic plague,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,AraC-family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30333962,PubMed,10.3389/fcimb.2018.00347,Front Cell Infect Microbiol. 2018 Oct 2;8:347,dongshengzhou1977@gmail.com,Modulation of biofilm and virulence-related genes by BfvR led to increased biofilm formation and reduced virulence of Y. pestis biovar Microtus.,H Fang 2018,2018,2 genes,"Fang-2018-BfvR, an AraC-Family Regulator, Cont",BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12469,PHI:8506,UniProt,P74989,GenBank,AAS61928,,,91001,hmsS,,,,,,,632,Yersinia pestis,229193,biovar Microtus strain 91001,pneumonic plague,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,hemin storage system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30333962,PubMed,10.3389/fcimb.2018.00347,Front Cell Infect Microbiol. 2018 Oct 2;8:347,dongshengzhou1977@gmail.com,Modulation of biofilm and virulence-related genes by BfvR led to increased biofilm formation and reduced virulence of Y. pestis biovar Microtus.,H Fang 2018,2018,2 genes,"Fang-2018-BfvR, an AraC-Family Regulator, Cont",BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12470,PHI:8507,UniProt,Q83F48,GenBank,AAO89667,,,RSA 493,nadB,,,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,putative L-aspartate oxidase,,,de novo NAD biosynthetic pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30315113,PubMed,10.1074/jbc.RA118.005190,J Biol Chem. 2018 Oct 12. pii: jbc.RA118.005190,fsansom@unimelb.edu.au,De novo NAD biosynthesis was required for intracellular replication of C. burnetii in both epithelial and macrophage-like cells.,M A Bitew 2018,2018,1 gene,Bitew-2018-De novo NAD synthesis is required f,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12471,PHI:8507,UniProt,Q83F48,GenBank,AAO89667,,,RSA 493,nadB,,R275L,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,putative L-aspartate oxidase,,,de novo NAD biosynthetic pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,30315113,PubMed,10.1074/jbc.RA118.005190,J Biol Chem. 2018 Oct 12. pii: jbc.RA118.005190,fsansom@unimelb.edu.au,Mutation of the critical amino acid residue R275 of NadB abolished enzymatic function in vitro.,M A Bitew 2018,2018,1 gene,Bitew-2018-De novo NAD synthesis is required f,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12472,PHI:8508,UniProt,A0A1S7DPR5,GenBank,AQY21106,,,HXb2,AS87_RS09170 (bioF),,,,,,,34085,Riemerella anatipestifer,,Yb2,chronic septicemia,birds,8839,Anas platyrhynchos (related: mallard),DEF cells,,,,8-amino-7-oxononanoate synthase,,,biotin biosynthesis,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,30279476,PubMed,10.1038/s41598-018-32905-1,Sci Rep. 2018 Oct 2;8(1):14645,yus@shvri.ac.cn,"The mutant strain Yb2ΔbioF showed an enhanced biofilm formation, increased adhesion and invasion capacities to duck embryo fibroblasts.",X Ren 2018,2018,1 gene,Ren-2018-Riemerella anatipestifer AS87_RS09170,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12473,PHI:8508,UniProt,A0A1S7DPR5,GenBank,AQY21106,,,HXb2,AS87_RS09170 (bioF),,,,,,,34085,Riemerella anatipestifer,,Yb2,chronic septicemia,birds,8839,Anas platyrhynchos (related: mallard),,,,blood,8-amino-7-oxononanoate synthase,,,biotin biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,30279476,PubMed,10.1038/s41598-018-32905-1,Sci Rep. 2018 Oct 2;8(1):14645,yus@shvri.ac.cn,The mutant strain Yb2ΔbioF exhibited reduced capacity to establish systemic infection in a duck infection model.,X Ren 2018,2018,1 gene,Ren-2018-Riemerella anatipestifer AS87_RS09170,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12474,PHI:8509,UniProt,G9MQ09,GenBank,EHK23958,,,Gv29-8,tex10,,,,,,,29875,Trichoderma virens,413071,Gv29-8,non-pathogenic: biocontrol,monocots,4577,Zea mays (related: maize),,,,root,non-ribosomal peptide synthetase,,,ferricrocin biosynthesis,increased virulence (hypervirulence),,,,,,reduced,,increased,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,30278887,PubMed,10.1016/j.bbrc.2018.09.170,Biochem Biophys Res Commun. 2018 Oct 28;505(2):606-611,c-kenerley@tamu.edu,"Disruption of tex10 gene using homologous recombination resulted in mutants with enhanced growth rate, reduced conidiation and hyper-sensitivity to oxidative stress as compared to wildtype strain.",P K Mukherjee 2018,2018,1 gene,"Mukherjee-2018-Ferricrocin, the intracellular",BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12475,PHI:8510,UniProt,A0A1R4AEC9,GenBank,SJL30117,,,SU60,PPAD,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),hTERT TIGKs cell line,,,gingival epithelium,peptidylarginine deiminase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30237466,PubMed,10.1038/s41598-018-32603-y,Sci Rep. 2018 Sep 20;8(1):14144,Piotr.Mydel@uib.no,"PPAD, although it is a potent modulator of the immune response, did not affect bacterial biofilm formation or the ability of P. gingivalis to adhere to and invade gingival epithelial cells.",A Aliko 2018,2018,1 gene,Aliko-2018-Impact of Porphyromonas gingivalis,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12476,PHI:8510,UniProt,A0A1R4AEC9,GenBank,SJL30117,,,SU60,PPAD,,C351A,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),hTERT TIGKs cell line,,,gingival epithelium,peptidylarginine deiminase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30237466,PubMed,10.1038/s41598-018-32603-y,Sci Rep. 2018 Sep 20;8(1):14144,Piotr.Mydel@uib.no,"PPAD, although it is a potent modulator of the immune response, did not affect bacterial biofilm formation or the ability of P. gingivalis to adhere to and invade gingival epithelial cells.",A Aliko 2018,2018,1 gene,Aliko-2018-Impact of Porphyromonas gingivalis,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12477,PHI:8511,UniProt,Q55RM6,GenBank,EAL20585,,,B-3501A,LAS17 (CNBE5050),chromosome 5,,,,,,5207,Cryptococcus neoformans,235443,var. grubii serotype A strain H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical protein,,,clathrin-mediated endocytosis pathway,reduced virulence,,,,,,,,reduced,,no,brefeldin A (BFA); monensin; NaCl; KCl; LiCl,brefeldin A (BFA): CHEBI:48080; monensin: CHEBI:27617; NaCl: CHEBI:26710; KCl: CHEBI:32588; LiCl: CHEBI:48607,,,,,gene deletion: full,,,YVS,30291809,PubMed,10.1111/cmi.12961,Cell Microbiol. 2018 Oct 6:e12961,kronstad@interchange.ubc.ca,"Clathrin-mediated endocytosis component Las17 was required for capsule and melanin production, and for virulence.",G Bairwa 2018,2018,1 gene,Bairwa-2018-Role of clathrin-mediated endocyto,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12478,PHI:8512,UniProt,D2TU76,GenBank,CBG90542,,,ICC168,cpxR,,,,,,PHI:8513,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,colon,two-component response regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30280092,PubMed,10.3389/fcimb.2018.00320,Front Cell Infect Microbiol. 2018 Sep 18;8:320,sebastien.faucher2@mcgill.ca,"It was found that as opposed to the ΔcpxRA strain, neither the ΔnlpE, ΔcpxP nor the ΔnlpEΔcpxP strains were significantly attenuated, and had similar in vivo localization to wild-type C. rodentium.",N Giannakopoulou 2018,2018,4 genes,Giannakopoulou-2018-The Virulence Effect of Cp,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12479,PHI:8513,UniProt,D2TU77,GenBank,CBG90543,,,ICC168,cpxA,,,,,,PHI:8512,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,colon,two-component sensor kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30280092,PubMed,10.3389/fcimb.2018.00320,Front Cell Infect Microbiol. 2018 Sep 18;8:320,sebastien.faucher2@mcgill.ca,"It was found that as opposed to the ΔcpxRA strain, neither the ΔnlpE, ΔcpxP nor the ΔnlpEΔcpxP strains were significantly attenuated, and had similar in vivo localization to wild-type C. rodentium.",N Giannakopoulou 2018,2018,4 genes,Giannakopoulou-2018-The Virulence Effect of Cp,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12480,PHI:8514,UniProt,D2TI83,GenBank,CBG86980,,,ICC168,nlpE,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,colon,outer-membrane lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30280092,PubMed,10.3389/fcimb.2018.00320,Front Cell Infect Microbiol. 2018 Sep 18;8:320,sebastien.faucher2@mcgill.ca,"It was found that as opposed to the ΔcpxRA strain, neither the ΔnlpE, ΔcpxP nor the ΔnlpEΔcpxP strains were significantly attenuated, and had similar in vivo localization to wild-type C. rodentium.",N Giannakopoulou 2018,2018,4 genes,Giannakopoulou-2018-The Virulence Effect of Cp,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12481,PHI:8515,UniProt,D2TU75,GenBank,CBG90541,,,ICC168,cpxP,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,colon,periplasmic protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30280092,PubMed,10.3389/fcimb.2018.00320,Front Cell Infect Microbiol. 2018 Sep 18;8:320,sebastien.faucher2@mcgill.ca,"It was found that as opposed to the ΔcpxRA strain, neither the ΔnlpE, ΔcpxP nor the ΔnlpEΔcpxP strains were significantly attenuated, and had similar in vivo localization to wild-type C. rodentium.",N Giannakopoulou 2018,2018,4 genes,Giannakopoulou-2018-The Virulence Effect of Cp,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12482,PHI:8514,UniProt,D2TI83,GenBank,CBG86980,,,ICC168,nlpE,,,,,,PHI:8515,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,colon,outer-membrane lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30280092,PubMed,10.3389/fcimb.2018.00320,Front Cell Infect Microbiol. 2018 Sep 18;8:320,sebastien.faucher2@mcgill.ca,"It was found that as opposed to the ΔcpxRA strain, neither the ΔnlpE, ΔcpxP nor the ΔnlpEΔcpxP strains were significantly attenuated, and had similar in vivo localization to wild-type C. rodentium.",N Giannakopoulou 2018,2018,4 genes,Giannakopoulou-2018-The Virulence Effect of Cp,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12483,PHI:8515,UniProt,D2TU75,GenBank,CBG90541,,,ICC168,cpxP,,,,,,PHI:8514,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,colon,periplasmic protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30280092,PubMed,10.3389/fcimb.2018.00320,Front Cell Infect Microbiol. 2018 Sep 18;8:320,sebastien.faucher2@mcgill.ca,"It was found that as opposed to the ΔcpxRA strain, neither the ΔnlpE, ΔcpxP nor the ΔnlpEΔcpxP strains were significantly attenuated, and had similar in vivo localization to wild-type C. rodentium.",N Giannakopoulou 2018,2018,4 genes,Giannakopoulou-2018-The Virulence Effect of Cp,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12484,PHI:8516,UniProt,A0A3Q0L2P3,GenBank,AAO09307,,,CMCP6,nab1 (VV1_0803),chromosome I,,,,,,672,Vibrio vulnificus,216895,CMCP6,vibriosis,crustaceans,6661,Artemia franciscana (no common name found),San Francisco Bay Brand ASF65031,,,napulii,N-acetylneuraminate cytidylyltransferase,,,NulO biosynthetic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30315110,PubMed,10.1074/jbc.RA118.004966,J Biol Chem. 2018 Oct 12. pii: jbc.RA118.004966,fboyd@udel.edu,ΔNab1 and Δnab2 mutant of V. vulnificus CMCP6 was defective in biofilm formation and NulO biosynthesis.,N D McDonald 2018,2018,2 genes,McDonald-2018-Structural and functional charac,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12485,PHI:8517,UniProt,A0A3Q0L2L4,GenBank,AAO09312,,,CMCP6,nab2 (VV1_0808),chromosome I,,,,,,672,Vibrio vulnificus,216895,CMCP6,vibriosis,crustaceans,6661,Artemia franciscana (no common name found),San Francisco Bay Brand ASF65031,,,napulii,N-acetylneuraminate synthase,,,NulO biosynthetic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30315110,PubMed,10.1074/jbc.RA118.004966,J Biol Chem. 2018 Oct 12. pii: jbc.RA118.004966,fboyd@udel.edu,ΔNab1 and Δnab2 mutant of V. vulnificus CMCP6 was defective in biofilm formation and NulO biosynthesis.,N D McDonald 2018,2018,2 genes,McDonald-2018-Structural and functional charac,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12486,PHI:8518,UniProt,A0A125YYK6,GenBank,EPT30740,,,ME49,TgIST,chromosome VI,,,,,,5811,Toxoplasma gondii,,type II strain ME49,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30283439,PubMed,10.3389/fimmu.2018.02073,Front Immunol. 2018 Sep 19;9:2073,myamamoto@biken.osaka-u.ac.jp,"Host gene alteration data available for ATG16L1, IDO1 and IDO2. An IFN-gamma-dependent reduction in TgIST-KO parasite numbers was observed, suggesting that TgIST promoted parasite growth in the IFN-gamma-post-stimulated human cells which was mainly due to inhibition of IDO1.",H Bando 2018,2018,1 gene,Bando-2018-Toxoplasma Effector TgIST Targets H,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12487,PHI:8518,UniProt,A0A125YYK6,GenBank,EPT30740,,,ME49,TgIST,chromosome VI,,,,,,5811,Toxoplasma gondii,,type II strain ME49,toxoplasmosis,primates,9606,Homo sapiens (related: human),Huh-7 cell line,,,hepatocyte,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30283439,PubMed,10.3389/fimmu.2018.02073,Front Immunol. 2018 Sep 19;9:2073,myamamoto@biken.osaka-u.ac.jp,"Host gene alteration data available for ATG16L1, IDO1 and IDO2. An IFN-gamma-dependent reduction in TgIST-KO parasite numbers was observed, suggesting that TgIST promoted parasite growth in the IFN-gamma-post-stimulated human cells which was mainly due to inhibition of IDO1.",H Bando 2018,2018,1 gene,Bando-2018-Toxoplasma Effector TgIST Targets H,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12488,PHI:8518,UniProt,A0A125YYK6,GenBank,EPT30740,,,ME49,TgIST,chromosome VI,,,,,,5811,Toxoplasma gondii,,type II strain ME49,toxoplasmosis,primates,9606,Homo sapiens (related: human),HAP1 cell line,,,HAP-1 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30283439,PubMed,10.3389/fimmu.2018.02073,Front Immunol. 2018 Sep 19;9:2073,myamamoto@biken.osaka-u.ac.jp,"Host gene alteration data available for ATG16L1, IDO1 and IDO2. An IFN-gamma-dependent reduction in TgIST-KO parasite numbers was observed, suggesting that TgIST promoted parasite growth in the IFN-gamma-post-stimulated human cells which was mainly due to inhibition of IDO1.",H Bando 2018,2018,1 gene,Bando-2018-Toxoplasma Effector TgIST Targets H,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12489,PHI:8519,UniProt,P9WNI7,GenBank,CCP45134,,,H37Rv,Rv2346c,H37Rv,,,,,,1773,Mycobacterium tuberculosis,419947,H37Ra,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,member of 6-kDa early secreted antigenic target family of proteins,,,P38/miRNA/NFκB pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30232332,PubMed,10.1038/s41426-018-0162-6,Emerg Microbes Infect. 2018 Sep 19;7(1):158,zhu1635253@163.com,Rv2346c inhibited the proliferation of BCG-infected macrophages and enhanced the survival of BCG in U937 and RAW264.7 macrophages.,J Yao 2018,2018,1 gene,Yao-2018-Rv2346c enhances mycobacterial surviv,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12490,PHI:8519,UniProt,P9WNI7,GenBank,CCP45134,,,H37Rv,Rv2346c,H37Rv,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,member of 6-kDa early secreted antigenic target family of proteins,,,P38/miRNA/NFκB pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30232332,PubMed,10.1038/s41426-018-0162-6,Emerg Microbes Infect. 2018 Sep 19;7(1):158,zhu1635253@163.com,Rv2346c inhibited the proliferation of BCG-infected macrophages and enhanced the survival of BCG in U937 and RAW264.7 macrophages.,J Yao 2018,2018,1 gene,Yao-2018-Rv2346c enhances mycobacterial surviv,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12491,PHI:8520,UniProt,G2WWV6,GenBank,EGY21211,,,VdLs.17,PevD1 (VDAG_02735),chromosome 3,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Guoxin,,,leaf; root,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30295911,PubMed,10.1093/jxb/ery351,J Exp Bot. 2018 Oct 5,qiudewen@caas.cn,V. dahliae secreted PevD1 to inhibit GhPR5 antifungal activity to overcome the host defence system.,Y Zhang 2018,2018,1 gene,Zhang-2018-Verticillium dahliae Alt a 1-like p,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12492,PHI:8520,UniProt,G2WWV6,GenBank,EGY21211,,,VdLs.17,PevD1 (VDAG_02735),chromosome 3,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Chuangxin,,,leaf; root,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30295911,PubMed,10.1093/jxb/ery351,J Exp Bot. 2018 Oct 5,qiudewen@caas.cn,V. dahliae secreted PevD1 to inhibit GhPR5 antifungal activity to overcome the host defence system.,Y Zhang 2018,2018,1 gene,Zhang-2018-Verticillium dahliae Alt a 1-like p,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12493,PHI:8520,UniProt,G2WWV6,GenBank,EGY21211,,,VdLs.17,PevD1 (VDAG_02735),chromosome 3,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,other evidence: transgenic plants,,,YVS,30295911,PubMed,10.1093/jxb/ery351,J Exp Bot. 2018 Oct 5,qiudewen@caas.cn,V. dahliae secreted PevD1 to inhibit GhPR5 antifungal activity to overcome the host defence system.,Y Zhang 2018,2018,1 gene,Zhang-2018-Verticillium dahliae Alt a 1-like p,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12494,PHI:8520,UniProt,G2WWV6,GenBank,EGY21211,,,VdLs.17,PevD1 (VDAG_02735),chromosome 3,PevD1-ΔSP,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation; other evidence: transgenic plants,,,YVS,30295911,PubMed,10.1093/jxb/ery351,J Exp Bot. 2018 Oct 5,qiudewen@caas.cn,V. dahliae secreted PevD1 to inhibit GhPR5 antifungal activity to overcome the host defence system.,Y Zhang 2018,2018,1 gene,Zhang-2018-Verticillium dahliae Alt a 1-like p,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12495,PHI:8520,UniProt,G2WWV6,GenBank,EGY21211,,,VdLs.17,PevD1 (VDAG_02735),chromosome 3,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30295911,PubMed,10.1093/jxb/ery351,J Exp Bot. 2018 Oct 5,qiudewen@caas.cn,V. dahliae secreted PevD1 to inhibit GhPR5 antifungal activity to overcome the host defence system.,Y Zhang 2018,2018,1 gene,Zhang-2018-Verticillium dahliae Alt a 1-like p,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12496,PHI:8520,UniProt,G2WWV6,GenBank,EGY21211,,,VdLs.17,PevD1 (VDAG_02735),chromosome 3,,,,,,27337,Verticillium dahliae,,,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30295911,PubMed,10.1093/jxb/ery351,J Exp Bot. 2018 Oct 5,qiudewen@caas.cn,V. dahliae secreted PevD1 to inhibit GhPR5 antifungal activity to overcome the host defence system.,Y Zhang 2018,2018,1 gene,Zhang-2018-Verticillium dahliae Alt a 1-like p,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12497,PHI:8521,UniProt,Q4WSZ7,GenBank,EAL90435,,,Af293,Kin1,chromosome 1,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,serine/threonine protein kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,caspofungin; nikkomycin Z; Congo red; voriconazole; calcofluor white,caspofungin: CHEBI:474180; nikkomycin Z: CHEBI:623918; Congo red: CHEBI:34653; voriconazole: CHEBI:10023; calcofluor white: CHEBI:50011,,,,,gene deletion: full,bimolecular fluorescence complementation,,YVS,30292408,PubMed,10.1016/j.bbrc.2018.09.186,Biochem Biophys Res Commun. 2018 Nov 2;505(3):740-746,bill.steinbach@duke.edu,Kin1 deletion in Aspergillus fumigatus did not affect hyphal growth and septation but resulted in differential susceptibility to antifungals targeting the cell wall and cell membrane.,P R Juvvadi 2018,2018,1 gene,Juvvadi-2018-Kin1 kinase localizes at the hyph,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12498,PHI:8522,UniProt,G4N8G2,GenBank,EHA51010,,,70-15,MoYPEL1 (MGG_06263.7),chromosome 4,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,hypothetical protein,,,mitogen-activated protein kinase (MAPK) pathway,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,"1-octacosanol: CHEBI:28243; 1,16-hexadecanediol: CAS no.: 7735-42-4","1-octacosanol: CHEBI:28243; 1,16-hexadecanediol CAS no.: CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,YVS,30262874,PubMed,10.1038/s41598-018-32633-6,Sci Rep. 2018 Sep 27;8(1):14461,kims@kangwon.ac.kr,"MoYPEL1 was essential for appressorium-mediated penetration, possibly, independent of cAMP-related pathway, and MoYPEL2 was necessary for the full virulence in M. oryzae.",J H Han 2018,2018,2 genes,Han-2018-Distinct roles of the YPEL gene famil,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12499,PHI:8523,UniProt,G4NDI1,GenBank,EHA49266,,,70-15,MoYPEL1 (MGG_06263.7),chromosome 5,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,hypothetical protein,,,mitogen-activated protein kinase (MAPK) pathway,reduced virulence,,no,,,,increased,,wild type,,no,"1-octacosanol: CHEBI:28243; 1,16-hexadecanediol: CAS no.: 7735-42-4","1-octacosanol: CHEBI:28243; 1,16-hexadecanediol CAS no.: CAS:7735-42-4",,,,,gene deletion: full; gene complementation,,,YVS,30262874,PubMed,10.1038/s41598-018-32633-6,Sci Rep. 2018 Sep 27;8(1):14461,kims@kangwon.ac.kr,"MoYPEL1 was essential for appressorium-mediated penetration, possibly, independent of cAMP-related pathway, and MoYPEL2 was necessary for the full virulence in M. oryzae.",J H Han 2018,2018,2 genes,Han-2018-Distinct roles of the YPEL gene famil,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12500,PHI:8522,UniProt,G4N8G2,GenBank,EHA51010,,,70-15,MoYPEL1 (MGG_06263.7),chromosome 4,,,,,PHI:8523,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,hypothetical protein,,,mitogen-activated protein kinase (MAPK) pathway,loss of pathogenicity,,no,,,,reduced,,wild type,,no,"1-octacosanol; 1,16-hexadecanediol","1-octacosanol: CHEBI:28243; 1,16-hexadecanediol CAS no.: CAS:7735-42-4",,,,,gene deletion: full,,,YVS,30262874,PubMed,10.1038/s41598-018-32633-6,Sci Rep. 2018 Sep 27;8(1):14461,kims@kangwon.ac.kr,"MoYPEL1 was essential for appressorium-mediated penetration, possibly, independent of cAMP-related pathway, and MoYPEL2 was necessary for the full virulence in M. oryzae.",J H Han 2018,2018,2 genes,Han-2018-Distinct roles of the YPEL gene famil,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12501,PHI:8523,UniProt,G4NDI1,GenBank,EHA49266,,,70-15,MoYPEL1 (MGG_06263.7),chromosome 5,,,,,PHI:8522,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,hypothetical protein,,,mitogen-activated protein kinase (MAPK) pathway,loss of pathogenicity,,no,,,,reduced,,wild type,,no,"1-octacosanol: CHEBI:28243; 1,16-hexadecanediol: CAS no.: 7735-42-4","1-octacosanol: CHEBI:28243; 1,16-hexadecanediol CAS no.: CAS:7735-42-4",,,,,gene deletion: full,,,YVS,30262874,PubMed,10.1038/s41598-018-32633-6,Sci Rep. 2018 Sep 27;8(1):14461,kims@kangwon.ac.kr,"MoYPEL1 was essential for appressorium-mediated penetration, possibly, independent of cAMP-related pathway, and MoYPEL2 was necessary for the full virulence in M. oryzae.",J H Han 2018,2018,2 genes,Han-2018-Distinct roles of the YPEL gene famil,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12502,PHI:8524,,no data found,,,,,,trans217,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12503,PHI:8525,,no data found,,,,,,trans3287,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12504,PHI:8524,,no data found,,,,,,trans217,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,small non-coding RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12505,PHI:8525,,no data found,,,,,,trans3287,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,small non-coding RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12506,PHI:8526,,no data found,,,,,,trans191,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12507,PHI:8526,,no data found,,,,,,trans191,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12508,PHI:8527,,no data found,,,,,,trans198,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12509,PHI:8528,,no data found,,,,,,trans202,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12510,PHI:8529,,no data found,,,,,,trans2192,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12511,PHI:8530,,no data found,,,,,,trans238,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12512,PHI:8531,,no data found,,,,,,trans1513,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12513,PHI:8532,,no data found,,,,,,trans3288,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12514,PHI:8533,,no data found,,,,,,trans3747,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12515,PHI:8534,,no data found,,,,,,cis3128,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12516,PHI:8535,,no data found,,,,,,cis954,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30326834,PubMed,10.1186/s12870-018-1470-7,BMC Plant Biol. 2018 Oct 16;18(1):237,xuheng@njau.edu.cn,Trans217 and trans3287 were essential not only for the formation of bacterial blight in a susceptible rice variety Nipponbare but also for the induction of hypersensitive response (HR) in nonhost plant tobacco.,Y Hu 2018,2018,12 genes,Hu-2018-Two virulent sRNAs identified by genom,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12517,PHI:8536,,no data found,,,,,,FaDHDPS1,,,,,,,282267,Fusarium asiaticum,,2021,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 5,,,inflorescence,dihydrodipicolinate synthase,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,reduced,,wild type,reduced,no,NaCl; KCl; H2O2; paraquat; Congo red; caffeine; SDS,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; paraquat: CHEBI:34905; Congo red: CHEBI:34653; caffeine: CHEBI:27732; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30290767,PubMed,10.1186/s12866-018-1268-7,BMC Microbiol. 2018 Oct 5;18(1):128,changjun-chen@njau.edu.cn,"Deletion of FaDHDPS1 resulted in tolerance to sodium pyruvate, lysine, low temperature and Congo red.",W Ren 2018,2018,1 gene,Ren-2018-Involvement of a dihydrodipicolinate,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12518,PHI:8537,UniProt,A0A177DXG4,GenBank,OWY53006.1,,,,AaMFS54,,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,major facilitator superfamily transporter,,,,reduced virulence,,,,,,reduced,,reduced,,no,"potassium superoxide; 2,3,5-triiodobenzoic acid; 2-chloro-5-hydroxypyridine; clotrimazole; fludioxonil; vinclozolin; iprodione; CuCl2; H2O2; hematoporphyrin","potassium superoxide CAS no.: CAS:12030-88-5; 2,3,5-triiodobenzoic acid: CHEBI:73175; 2-chloro-5-hydroxypyridine CAS no.: CAS:41288-96-4; clotrimazole: CHEBI:3764; fludioxonil: CAS:131341-86-1; vinclozolin: CHEBI:9986; iprodione: CHEBI:28909; CuCl2: CHEBI:49553; H2O2: CHEBI:16240; hematoporphyrin: CHEBI:36162",,,,,gene deletion: full; gene complementation,,,YVS,30279684,PubMed,10.3389/fmicb.2018.02229,Front Microbiol. 2018 Sep 18;9:2229,krchung@nchu.edu.tw,"Fungal mutant lacking AaMFS54 produced fewer conidia and increased sensitivity to many potent oxidants, xenobiotics and fungicides.",H C Lin 2018,2018,1 gene,Lin-2018-A Major Facilitator Superfamily Trans,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12519,PHI:8538,UniProt,G4NFA2,GenBank,EHA47284,,,70-15,MoSNF7 (MGG_04174),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,SNF7 family protein involved in endocytosis and autophagy,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,NaCl; KCl; sorbitol; H2O2; glutathione; sodium dodecyl sulphate (SDS); calcofluor white (CFW); Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; glutathione: CHEBI:16856; sodium dodecyl sulphate (SDS): CHEBI:8984; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30240788,PubMed,10.1016/j.fgb.2018.09.005,Fungal Genet Biol. 2018 Sep 18;121:29-45,liangyh@njau.edu.cn,"The decreased vegetative growth and pathogenicity of ΔMosnf7 rice blast fungus M. oryzae, was partly due to the conservative roles of MoSnf7 in vesicle trafficking and autophagy pathway.",J Cheng 2018,2018,1 gene,Cheng-2018-Functional analysis of MoSnf7 in Ma,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12520,PHI:8538,UniProt,G4NFA2,GenBank,EHA47284,,,70-15,MoSNF7 (MGG_04174),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,SNF7 family protein involved in endocytosis and autophagy,,,,reduced virulence,,,yes,yes,,reduced,reduced,reduced,,no,NaCl; KCl; sorbitol; H2O2; glutathione; sodium dodecyl sulphate (SDS); calcofluor white (CFW); Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; glutathione: CHEBI:16856; sodium dodecyl sulphate (SDS): CHEBI:8984; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30240788,PubMed,10.1016/j.fgb.2018.09.005,Fungal Genet Biol. 2018 Sep 18;121:29-45,liangyh@njau.edu.cn,"The decreased vegetative growth and pathogenicity of ΔMosnf7 rice blast fungus M. oryzae, was partly due to the conservative roles of MoSnf7 in vesicle trafficking and autophagy pathway.",J Cheng 2018,2018,1 gene,Cheng-2018-Functional analysis of MoSnf7 in Ma,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12521,PHI:8539,,no data found,GenBank,AGQ27279,,,HSC5,CcpA (L897_02310),,,,,,,1314,Streptococcus pyogenes,,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,subcutaneous tissue,DNA-binding transcriptional regulator,,,Embden-Meyerhof-Parnas (EMP) glycolytic pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30250043,PubMed,10.1038/s41598-018-32558-0,Sci Rep. 2018 Sep 24;8(1):14254,caparon@wustl.edu,"The data showed that while ΔCcpA and T307Y had colonization profiles that differed significantly from WT, as ΔCcpA's ability to colonize was attenuated, while T307Y's was enhanced.",E Paluscio 2018,2018,1 gene,Paluscio-2018-CcpA Coordinates Growth_Damage B,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12522,PHI:8539,,no data found,GenBank,AGQ27279,,,HSC5,CcpA (L897_02310),,T307Y,,,,,1314,Streptococcus pyogenes,,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),SKH1,,,subcutaneous tissue,DNA-binding transcriptional regulator,,,Embden-Meyerhof-Parnas (EMP) glycolytic pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,YVS,30250043,PubMed,10.1038/s41598-018-32558-0,Sci Rep. 2018 Sep 24;8(1):14254,caparon@wustl.edu,"The data showed that while ΔCcpA and T307Y had colonization profiles that differed significantly from WT, as ΔCcpA's ability to colonize was attenuated, while T307Y's was enhanced.",E Paluscio 2018,2018,1 gene,Paluscio-2018-CcpA Coordinates Growth_Damage B,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12523,PHI:8539,,no data found,GenBank,AGQ27279,,,HSC5,CcpA (L897_02310),,,,,,,1314,Streptococcus pyogenes,,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,vaginal mucosa,DNA-binding transcriptional regulator,,,Embden-Meyerhof-Parnas (EMP) glycolytic pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30250043,PubMed,10.1038/s41598-018-32558-0,Sci Rep. 2018 Sep 24;8(1):14254,caparon@wustl.edu,"The data showed that while ΔCcpA and T307Y had colonization profiles that differed significantly from WT, as ΔCcpA's ability to colonize was attenuated, while T307Y's was enhanced.",E Paluscio 2018,2018,1 gene,Paluscio-2018-CcpA Coordinates Growth_Damage B,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12524,PHI:8539,,no data found,GenBank,AGQ27279,,,HSC5,CcpA (L897_02310),,T307Y,,,,,1314,Streptococcus pyogenes,,HSC5,skin lesion,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,vaginal mucosa,DNA-binding transcriptional regulator,,,Embden-Meyerhof-Parnas (EMP) glycolytic pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,YVS,30250043,PubMed,10.1038/s41598-018-32558-0,Sci Rep. 2018 Sep 24;8(1):14254,caparon@wustl.edu,"The data showed that while ΔCcpA and T307Y had colonization profiles that differed significantly from WT, as ΔCcpA's ability to colonize was attenuated, while T307Y's was enhanced.",E Paluscio 2018,2018,1 gene,Paluscio-2018-CcpA Coordinates Growth_Damage B,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12525,PHI:8540,UniProt,Q2KKC3,GenBank,AAX97438,,,ATCC 29212,OadA,,,,,,,1351,Enterococcus faecalis,,JH2-2,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,carboxyl transferase,,,citrate fermentation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30335810,PubMed,10.1371/journal.pone.0205787,PLoS One. 2018 Oct 18;13(10):e0205787,blancato@ibr-conicet.gov.ar,E.faecalis citrate fermentation-deficient strain and strains with deletions in the oxaloacetate decarboxylase subunits or in the a-acetolactate synthase were less pathogenic for Galleria mellonella larvae than the wild type.,G P Martino 2018,2018,4 genes,Martino-2018-Implications of the expression of,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12526,PHI:8541,UniProt,Q2KKC0,GenBank,AAX97432,,,ATCC 29212,OadB,,,,,,,1351,Enterococcus faecalis,,JH2-2,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na+ membrane pump,,,citrate fermentation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30335810,PubMed,10.1371/journal.pone.0205787,PLoS One. 2018 Oct 18;13(10):e0205787,blancato@ibr-conicet.gov.ar,E.faecalis citrate fermentation-deficient strain and strains with deletions in the oxaloacetate decarboxylase subunits or in the a-acetolactate synthase were less pathogenic for Galleria mellonella larvae than the wild type.,G P Martino 2018,2018,4 genes,Martino-2018-Implications of the expression of,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12527,PHI:8542,UniProt,Q2KKC1,GenBank,AAX97431,,,ATCC 29212,OadD,,,,,,,1351,Enterococcus faecalis,,JH2-2,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,biotin acceptor protein,,,citrate fermentation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30335810,PubMed,10.1371/journal.pone.0205787,PLoS One. 2018 Oct 18;13(10):e0205787,blancato@ibr-conicet.gov.ar,E.faecalis citrate fermentation-deficient strain and strains with deletions in the oxaloacetate decarboxylase subunits or in the a-acetolactate synthase were less pathogenic for Galleria mellonella larvae than the wild type.,G P Martino 2018,2018,4 genes,Martino-2018-Implications of the expression of,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12528,PHI:8543,UniProt,Q836A5,GenBank,AAO81010,,,V583,AlsS,,,,,,,1351,Enterococcus faecalis,,JH2-2,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,α-acetolactate synthase,,,citrate fermentation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30335810,PubMed,10.1371/journal.pone.0205787,PLoS One. 2018 Oct 18;13(10):e0205787,blancato@ibr-conicet.gov.ar,E.faecalis citrate fermentation-deficient strain and strains with deletions in the oxaloacetate decarboxylase subunits or in the a-acetolactate synthase were less pathogenic for Galleria mellonella larvae than the wild type.,G P Martino 2018,2018,4 genes,Martino-2018-Implications of the expression of,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12529,PHI:8540,UniProt,Q2KKC3,GenBank,AAX97438,,,ATCC 29212,OadA,,,,,,,1351,Enterococcus faecalis,,JH2-2,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,blood,carboxyl transferase,,,citrate fermentation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30335810,PubMed,10.1371/journal.pone.0205787,PLoS One. 2018 Oct 18;13(10):e0205787,blancato@ibr-conicet.gov.ar,Citrate fermentation pathway mutants grew less effectively in blood and urine than the WT. Tissue: defibrinated blood,G P Martino 2018,2018,4 genes,Martino-2018-Implications of the expression of,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12530,PHI:8541,UniProt,Q2KKC0,GenBank,AAX97432,,,ATCC 29212,OadB,,,,,,,1351,Enterococcus faecalis,,JH2-2,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,blood,Na+ membrane pump,,,citrate fermentation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30335810,PubMed,10.1371/journal.pone.0205787,PLoS One. 2018 Oct 18;13(10):e0205787,blancato@ibr-conicet.gov.ar,Citrate fermentation pathway mutants grew less effectively in blood and urine than the WT. Tissue: defibrinated blood,G P Martino 2018,2018,4 genes,Martino-2018-Implications of the expression of,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12531,PHI:8542,UniProt,Q2KKC1,GenBank,AAX97431,,,ATCC 29212,OadD,,,,,,,1351,Enterococcus faecalis,,JH2-2,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),,,,blood,biotin acceptor protein,,,citrate fermentation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30335810,PubMed,10.1371/journal.pone.0205787,PLoS One. 2018 Oct 18;13(10):e0205787,blancato@ibr-conicet.gov.ar,Citrate fermentation pathway mutants grew less effectively in blood and urine than the WT. Tissue: defibrinated blood,G P Martino 2018,2018,4 genes,Martino-2018-Implications of the expression of,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12532,PHI:8540,UniProt,Q2KKC3,GenBank,AAX97438,,,ATCC 29212,OadA,,,,,,,1351,Enterococcus faecalis,,JH2-2,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,carboxyl transferase,,,citrate fermentation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30335810,PubMed,10.1371/journal.pone.0205787,PLoS One. 2018 Oct 18;13(10):e0205787,blancato@ibr-conicet.gov.ar,Citrate fermentation pathway mutants grew less effectively in blood and urine than the WT.,G P Martino 2018,2018,4 genes,Martino-2018-Implications of the expression of,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12533,PHI:8541,UniProt,Q2KKC0,GenBank,AAX97432,,,ATCC 29212,OadB,,,,,,,1351,Enterococcus faecalis,,JH2-2,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,Na+ membrane pump,,,citrate fermentation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30335810,PubMed,10.1371/journal.pone.0205787,PLoS One. 2018 Oct 18;13(10):e0205787,blancato@ibr-conicet.gov.ar,Citrate fermentation pathway mutants grew less effectively in blood and urine than the WT.,G P Martino 2018,2018,4 genes,Martino-2018-Implications of the expression of,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12534,PHI:8542,UniProt,Q2KKC1,GenBank,AAX97431,,,ATCC 29212,OadD,,,,,,,1351,Enterococcus faecalis,,JH2-2,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,biotin acceptor protein,,,citrate fermentation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30335810,PubMed,10.1371/journal.pone.0205787,PLoS One. 2018 Oct 18;13(10):e0205787,blancato@ibr-conicet.gov.ar,Citrate fermentation pathway mutants grew less effectively in blood and urine than the WT.,G P Martino 2018,2018,4 genes,Martino-2018-Implications of the expression of,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12535,PHI:8544,UniProt,E9R0F1,GenBank,EAL90699,,,Af293,CcpA (Afu1g13670),chromosome 1,,,,,,746128,Aspergillus fumigatus,,D141,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,conidial cell wall protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30279286,PubMed,10.1128/mBio.01557-18,MBio. 2018 Oct 2;9(5). pii: e01557-18,axel.brakhage@leibniz-hki.de,CcpA served as a conidial stealth protein by altering the conidial surface structure to minimize innate immune recognition.,V Voltersen 2018,2018,1 gene,Voltersen-2018-Proteome Analysis Reveals the C,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12536,PHI:8544,UniProt,E9R0F1,GenBank,EAL90699,,,Af293,CcpA (Afu1g13670),chromosome 1,,,,,,746128,Aspergillus fumigatus,,D141,aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,conidial cell wall protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30279286,PubMed,10.1128/mBio.01557-18,MBio. 2018 Oct 2;9(5). pii: e01557-18,axel.brakhage@leibniz-hki.de,CcpA served as a conidial stealth protein by altering the conidial surface structure to minimize innate immune recognition.,V Voltersen 2018,2018,1 gene,Voltersen-2018-Proteome Analysis Reveals the C,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12537,PHI:8545,UniProt,P16575,GenBank,CAE42160,,,Tohama I,BvgS,,BvgSΔ65,,,,,520,Bordetella pertussis,,BPSM,pertussis,rodents,10090,Mus musculus (related: house mouse),BALB/cByJ,,,nose; lung,virulence sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,MgSO4,MgSO4: CHEBI:32599,,,,,gene mutation,,,YVS,30307950,PubMed,10.1371/journal.pone.0204861,PLoS One. 2018 Oct 11;13(10):e0204861,francoise.jacob@ibl.cnrs.fr,Recombinant strain expressing moderately lower levels of the virulence genes than its wild type parent was as efficient at colonizing both organs.,E Lesne 2018,2018,1 gene,Lesne-2018-Distinct virulence ranges for infec,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12538,PHI:8546,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),hMDMs,,,macrophage,"candidalysin, a cytolytic peptide toxin",,,,reduced virulence,,,,,,,,,,no,cytochalasin D; nigericin; KCl; glibenclamide; DMSO; H2O2,cytochalasin D: CHEBI:529996; nigericin: CHEBI:7569; KCl: CHEBI:32588; glibenclamide: CHEBI:5441; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30323213,PubMed,10.1038/s41467-018-06607-1,Nat Commun. 2018 Oct 15;9(1):4260,bernhard.hube@leibniz-hki.de,Candidalysin was a key driver of inflammasome-independent cytolysis of macrophages and dendritic cells upon infection with C. albicans.,L Kasper 2018,2018,1 gene,Kasper-2018-The fungal peptide toxin Candidaly,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12539,PHI:8546,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,ECE1Δ184–279,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),hMDMs,,,macrophage,"candidalysin, a cytolytic peptide toxin",,,,reduced virulence,,,,,,,,,,no,cytochalasin D; nigericin; KCl; glibenclamide; DMSO; H2O2,cytochalasin D: CHEBI:529996; nigericin: CHEBI:7569; KCl: CHEBI:32588; glibenclamide: CHEBI:5441; H2O2: CHEBI:16240,,,,,gene deletion: partial; gene complementation,,,YVS,30323213,PubMed,10.1038/s41467-018-06607-1,Nat Commun. 2018 Oct 15;9(1):4260,bernhard.hube@leibniz-hki.de,Candidalysin was a key driver of inflammasome-independent cytolysis of macrophages and dendritic cells upon infection with C. albicans.,L Kasper 2018,2018,1 gene,Kasper-2018-The fungal peptide toxin Candidaly,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12540,PHI:8546,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney,"candidalysin, a cytolytic peptide toxin",,,,reduced virulence,,,,,,,,,,no,cytochalasin D; nigericin; KCl; glibenclamide; DMSO; H2O2,cytochalasin D: CHEBI:529996; nigericin: CHEBI:7569; KCl: CHEBI:32588; glibenclamide: CHEBI:5441; H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,30323213,PubMed,10.1038/s41467-018-06607-1,Nat Commun. 2018 Oct 15;9(1):4260,bernhard.hube@leibniz-hki.de,Candidalysin was a key driver of inflammasome-independent cytolysis of macrophages and dendritic cells upon infection with C. albicans.,L Kasper 2018,2018,1 gene,Kasper-2018-The fungal peptide toxin Candidaly,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12541,PHI:8546,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,"candidalysin, a cytolytic peptide toxin",,,,unaffected pathogenicity,,,,,,,,,,no,cytochalasin D; nigericin; KCl; glibenclamide; DMSO; H2O2,cytochalasin D: CHEBI:529996; nigericin: CHEBI:7569; KCl: CHEBI:32588; glibenclamide: CHEBI:5441; H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,30323213,PubMed,10.1038/s41467-018-06607-1,Nat Commun. 2018 Oct 15;9(1):4260,bernhard.hube@leibniz-hki.de,Candidalysin was a key driver of inflammasome-independent cytolysis of macrophages and dendritic cells upon infection with C. albicans.,L Kasper 2018,2018,1 gene,Kasper-2018-The fungal peptide toxin Candidaly,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12542,PHI:8546,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),mBMDMs,,,bone marrow-derived macrophage,"candidalysin, a cytolytic peptide toxin",,,,unaffected pathogenicity,,,,,,,,,,no,cytochalasin D; nigericin; KCl; glibenclamide; DMSO; H2O2,cytochalasin D: CHEBI:529996; nigericin: CHEBI:7569; KCl: CHEBI:32588; glibenclamide: CHEBI:5441; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30323213,PubMed,10.1038/s41467-018-06607-1,Nat Commun. 2018 Oct 15;9(1):4260,bernhard.hube@leibniz-hki.de,Candidalysin was a key driver of inflammasome-independent cytolysis of macrophages and dendritic cells upon infection with C. albicans.,L Kasper 2018,2018,1 gene,Kasper-2018-The fungal peptide toxin Candidaly,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12543,PHI:8546,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,ECE1Δ184–279,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),mBMDMs,,,bone marrow-derived macrophage,"candidalysin, a cytolytic peptide toxin",,,,unaffected pathogenicity,,,,,,,,,,no,cytochalasin D; nigericin; KCl; glibenclamide; DMSO; H2O2,cytochalasin D: CHEBI:529996; nigericin: CHEBI:7569; KCl: CHEBI:32588; glibenclamide: CHEBI:5441; H2O2: CHEBI:16240,,,,,gene deletion: partial; gene complementation,,,YVS,30323213,PubMed,10.1038/s41467-018-06607-1,Nat Commun. 2018 Oct 15;9(1):4260,bernhard.hube@leibniz-hki.de,Candidalysin was a key driver of inflammasome-independent cytolysis of macrophages and dendritic cells upon infection with C. albicans.,L Kasper 2018,2018,1 gene,Kasper-2018-The fungal peptide toxin Candidaly,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12544,PHI:8546,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),mBMDCs,,,bone marrow-derived dendritic cell,"candidalysin, a cytolytic peptide toxin",,,,unaffected pathogenicity,,,,,,,,,,no,cytochalasin D; nigericin; KCl; glibenclamide; DMSO; H2O2,cytochalasin D: CHEBI:529996; nigericin: CHEBI:7569; KCl: CHEBI:32588; glibenclamide: CHEBI:5441; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30323213,PubMed,10.1038/s41467-018-06607-1,Nat Commun. 2018 Oct 15;9(1):4260,bernhard.hube@leibniz-hki.de,Candidalysin was a key driver of inflammasome-independent cytolysis of macrophages and dendritic cells upon infection with C. albicans.,L Kasper 2018,2018,1 gene,Kasper-2018-The fungal peptide toxin Candidaly,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12545,PHI:8546,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,ECE1Δ184–279,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),mBMDCs,,,bone marrow-derived dendritic cell,"candidalysin, a cytolytic peptide toxin",,,,unaffected pathogenicity,,,,,,,,,,no,cytochalasin D; nigericin; KCl; glibenclamide; DMSO; H2O2,cytochalasin D: CHEBI:529996; nigericin: CHEBI:7569; KCl: CHEBI:32588; glibenclamide: CHEBI:5441; H2O2: CHEBI:16240,,,,,gene deletion: partial; gene complementation,,,YVS,30323213,PubMed,10.1038/s41467-018-06607-1,Nat Commun. 2018 Oct 15;9(1):4260,bernhard.hube@leibniz-hki.de,Candidalysin was a key driver of inflammasome-independent cytolysis of macrophages and dendritic cells upon infection with C. albicans.,L Kasper 2018,2018,1 gene,Kasper-2018-The fungal peptide toxin Candidaly,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12546,PHI:8547,UniProt,P54292,GenBank,AAC44036,,,PAO1,RhlR,chromosome 1,,,,,,287,Pseudomonas aeruginosa,,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,regulatory protein,,,quorum sensing (QS) pathway,loss of pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene mutation; gene complementation,,,YVS,30224496,PubMed,10.1073/pnas.1814023115,Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9411-E9418,bbassler@princeton.edu,PqsE-derived alternative ligand was essential to activate RhlR to promote virulence gene expression in both the C. elegans and the murine animal models.,S Mukherjee 2018,2018,3 genes,Mukherjee-2018-The PqsE and RhlR proteins are,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12547,PHI:8548,UniProt,A0A0H2ZEE6,GenBank,ABJ12731,,,UCBPP-PA14,rhlI,,,,,,,287,Pseudomonas aeruginosa,,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,autoinducer synthesis protein,,,quorum sensing (QS) pathway,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene mutation,,,YVS,30224496,PubMed,10.1073/pnas.1814023115,Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9411-E9418,bbassler@princeton.edu,PqsE-derived alternative ligand was essential to activate RhlR to promote virulence gene expression in both the C. elegans and the murine animal models.,S Mukherjee 2018,2018,3 genes,Mukherjee-2018-The PqsE and RhlR proteins are,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12548,PHI:8549,UniProt,A0A0H2Z6F6,GenBank,ABJ10164,,,UCBPP-PA14,PqsE,,,,,,,287,Pseudomonas aeruginosa,,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,quinolone signal response protein,,,quorum sensing (QS) pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30224496,PubMed,10.1073/pnas.1814023115,Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9411-E9418,bbassler@princeton.edu,PqsE-derived alternative ligand was essential to activate RhlR to promote virulence gene expression in both the C. elegans and the murine animal models.,S Mukherjee 2018,2018,3 genes,Mukherjee-2018-The PqsE and RhlR proteins are,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12549,PHI:8548,UniProt,A0A0H2ZEE6,GenBank,ABJ12731,,,UCBPP-PA14,rhlI,,,,,,PHI:8549,287,Pseudomonas aeruginosa,,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,autoinducer synthesis protein,,,quorum sensing (QS) pathway,loss of pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene mutation,,,YVS,30224496,PubMed,10.1073/pnas.1814023115,Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9411-E9418,bbassler@princeton.edu,PqsE-derived alternative ligand was essential to activate RhlR to promote virulence gene expression in both the C. elegans and the murine animal models.,S Mukherjee 2018,2018,3 genes,Mukherjee-2018-The PqsE and RhlR proteins are,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12550,PHI:8549,UniProt,A0A0H2Z6F6,GenBank,ABJ10164,,,UCBPP-PA14,PqsE,,,,,,PHI:8548,287,Pseudomonas aeruginosa,,PA14,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,quinolone signal response protein,,,quorum sensing (QS) pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30224496,PubMed,10.1073/pnas.1814023115,Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9411-E9418,bbassler@princeton.edu,PqsE-derived alternative ligand was essential to activate RhlR to promote virulence gene expression in both the C. elegans and the murine animal models.,S Mukherjee 2018,2018,3 genes,Mukherjee-2018-The PqsE and RhlR proteins are,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12551,PHI:8547,UniProt,P54292,GenBank,AAC44036,,,PAO1,RhlR,chromosome 1,,,,,,287,Pseudomonas aeruginosa,,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,regulatory protein,,,quorum sensing (QS) pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation; gene complementation,,,YVS,30224496,PubMed,10.1073/pnas.1814023115,Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9411-E9418,bbassler@princeton.edu,PqsE-derived alternative ligand was essential to activate RhlR to promote virulence gene expression in both the C. elegans and the murine animal models.,S Mukherjee 2018,2018,3 genes,Mukherjee-2018-The PqsE and RhlR proteins are,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12552,PHI:8548,UniProt,A0A0H2ZEE6,GenBank,ABJ12731,,,UCBPP-PA14,rhlI,,,,,,,287,Pseudomonas aeruginosa,,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,autoinducer synthesis protein,,,quorum sensing (QS) pathway,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene mutation,,,YVS,30224496,PubMed,10.1073/pnas.1814023115,Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9411-E9418,bbassler@princeton.edu,PqsE-derived alternative ligand was essential to activate RhlR to promote virulence gene expression in both the C. elegans and the murine animal models.,S Mukherjee 2018,2018,3 genes,Mukherjee-2018-The PqsE and RhlR proteins are,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12553,PHI:8549,UniProt,A0A0H2Z6F6,GenBank,ABJ10164,,,UCBPP-PA14,PqsE,,,,,,,287,Pseudomonas aeruginosa,,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,quinolone signal response protein,,,quorum sensing (QS) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30224496,PubMed,10.1073/pnas.1814023115,Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9411-E9418,bbassler@princeton.edu,PqsE-derived alternative ligand was essential to activate RhlR to promote virulence gene expression in both the C. elegans and the murine animal models.,S Mukherjee 2018,2018,3 genes,Mukherjee-2018-The PqsE and RhlR proteins are,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12554,PHI:8548,UniProt,A0A0H2ZEE6,GenBank,ABJ12731,,,UCBPP-PA14,rhlI,,,,,,PHI:8549,287,Pseudomonas aeruginosa,,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,autoinducer synthesis protein,,,quorum sensing (QS) pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation,,,YVS,30224496,PubMed,10.1073/pnas.1814023115,Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9411-E9418,bbassler@princeton.edu,PqsE-derived alternative ligand was essential to activate RhlR to promote virulence gene expression in both the C. elegans and the murine animal models.,S Mukherjee 2018,2018,3 genes,Mukherjee-2018-The PqsE and RhlR proteins are,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12555,PHI:8549,UniProt,A0A0H2Z6F6,GenBank,ABJ10164,,,UCBPP-PA14,PqsE,,,,,,PHI:8548,287,Pseudomonas aeruginosa,,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,quinolone signal response protein,,,quorum sensing (QS) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30224496,PubMed,10.1073/pnas.1814023115,Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9411-E9418,bbassler@princeton.edu,PqsE-derived alternative ligand was essential to activate RhlR to promote virulence gene expression in both the C. elegans and the murine animal models.,S Mukherjee 2018,2018,3 genes,Mukherjee-2018-The PqsE and RhlR proteins are,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12556,PHI:8550,UniProt,B5LUS3,GenBank,ACG80381,,,,PsMAD1,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,MADS-box transcription factor,,,,reduced virulence,,,,,,,reduced,wild type,,no,,,,,,,gene disruption,,,YVS,23840763,PubMed,10.1371/journal.pone.0067670,PLoS One. 2013 Jun 28;8(6):e67670,wangyc@njau.edu.cn,"PsMAD1 was required for sporangia cleavage during zoospore development, leading to the defects in zoospore release.",L Lin 2018,2018,1 gene,Lin-2018-The MADS-box Transcription Factor PsM,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12557,PHI:8551,,no data found,GenBank,AVN85554,,,D39V,BriC,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx,competence-induced protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30308062,PubMed,10.1371/journal.ppat.1007328,PLoS Pathog. 2018 Oct 11;14(10):e1007328,lhiller@andrew.cmu.edu,BriC expression induced by ComE led to increases in biofilm biomass and thickness at 72h and promoted nasopharyngeal colonization in the murine model.,S D Aggarwal 2018,2018,2 genes,Aggarwal-2018-Function of BriC peptide in the,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12558,PHI:8551,,no data found,GenBank,AVN85554,,,D39V,BriC,,disruption of the ComE-binding box (D39ΔbriC::PbriCShuffled ComE-box-briC) within the briC promoter,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx,competence-induced protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation,,,YVS,30308062,PubMed,10.1371/journal.ppat.1007328,PLoS Pathog. 2018 Oct 11;14(10):e1007328,lhiller@andrew.cmu.edu,BriC expression induced by ComE led to increases in biofilm biomass and thickness at 72h and promoted nasopharyngeal colonization in the murine model.,S D Aggarwal 2018,2018,2 genes,Aggarwal-2018-Function of BriC peptide in the,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12559,PHI:8552,UniProt,Q79CK7,GenBank,AAC44897,,,R6x,ComE,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx,master regulator of competence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30308062,PubMed,10.1371/journal.ppat.1007328,PLoS Pathog. 2018 Oct 11;14(10):e1007328,lhiller@andrew.cmu.edu,BriC expression induced by ComE led to increases in biofilm biomass and thickness at 72h and promoted nasopharyngeal colonization in the murine model.,S D Aggarwal 2018,2018,2 genes,Aggarwal-2018-Function of BriC peptide in the,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12560,PHI:8551,,no data found,GenBank,AVN85554,,,D39V,BriC,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx,competence-induced protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30308062,PubMed,10.1371/journal.ppat.1007328,PLoS Pathog. 2018 Oct 11;14(10):e1007328,lhiller@andrew.cmu.edu,"Overexpression of briC by the long promoter fully rescued the comE-deletion induced biofilm defect in vitro, and partially in vivo.",S D Aggarwal 2018,2018,2 genes,Aggarwal-2018-Function of BriC peptide in the,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12561,PHI:8553,UniProt,A0A2X6J1R3,GenBank,SVF15463,,,VREC0288,hcp1,,,,,,,562,Escherichia coli,,CE129,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,embryonic fibroblast cell line,hemolysin co-regulation protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30247772,PubMed,10.1002/jobm.201800156,J Basic Microbiol. 2018 Nov;58(11):938-946,yzgqzhu@yzu.edu.cn,Deletion of hcp1 and hcp2 exerted a negative effect on the ability of APEC adhering to DF1 cells.,X Ding 2018,2018,2 genes,Ding-2018-The different roles of hcp1 and hcp2,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12562,PHI:8554,UniProt,A0A0G3K3H0,GenBank,AKK46827,,,PCN033,hcp2,,,,,,,562,Escherichia coli,,CE129,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,embryonic fibroblast cell line,hemolysin co-regulation protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30247772,PubMed,10.1002/jobm.201800156,J Basic Microbiol. 2018 Nov;58(11):938-946,yzgqzhu@yzu.edu.cn,Deletion of hcp1 and hcp2 exerted a negative effect on the ability of APEC adhering to DF1 cells.,X Ding 2018,2018,2 genes,Ding-2018-The different roles of hcp1 and hcp2,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12563,PHI:8553,UniProt,A0A2X6J1R3,GenBank,SVF15463,,,VREC0288,hcp1,,,,,,PHI:8554,562,Escherichia coli,,CE129,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,embryonic fibroblast cell line,hemolysin co-regulation protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30247772,PubMed,10.1002/jobm.201800156,J Basic Microbiol. 2018 Nov;58(11):938-946,yzgqzhu@yzu.edu.cn,Deletion of hcp1 and hcp2 exerted a negative effect on the ability of APEC adhering to DF1 cells.,X Ding 2018,2018,2 genes,Ding-2018-The different roles of hcp1 and hcp2,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12564,PHI:8554,UniProt,A0A0G3K3H0,GenBank,AKK46827,,,PCN033,hcp2,,,,,,PHI:8553,562,Escherichia coli,,CE129,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,embryonic fibroblast cell line,hemolysin co-regulation protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30247772,PubMed,10.1002/jobm.201800156,J Basic Microbiol. 2018 Nov;58(11):938-946,yzgqzhu@yzu.edu.cn,Deletion of hcp1 and hcp2 exerted a negative effect on the ability of APEC adhering to DF1 cells.,X Ding 2018,2018,2 genes,Ding-2018-The different roles of hcp1 and hcp2,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12565,PHI:8555,UniProt,F4RBY2,GenBank,EGG10259,,,98AG31,Mlp124478,,,,,,,203908,Melampsora laricis-populina,,,leaf rust,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30283062,PubMed,10.1038/s41598-018-32825-0,Sci Rep. 2018 Oct 3;8(1):14718,hugo.germain@uqtr.ca,"Stable constitutive expression of Mlp124478 in A. thaliana repressed the expression of genes involved in immune responses, and also altered leaf morphology by increasing the waviness of rosette leaves.",M B Ahmed 2018,2018,1 gene,Ahmed-2018-A rust fungal effector binds plant,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12566,PHI:8555,UniProt,F4RBY2,GenBank,EGG10259,,,98AG31,Mlp124478,,,,,,,203908,Melampsora laricis-populina,,,leaf rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30283062,PubMed,10.1038/s41598-018-32825-0,Sci Rep. 2018 Oct 3;8(1):14718,hugo.germain@uqtr.ca,"Stable constitutive expression of Mlp124478 in A. thaliana repressed the expression of genes involved in immune responses, and also altered leaf morphology by increasing the waviness of rosette leaves.",M B Ahmed 2018,2018,1 gene,Ahmed-2018-A rust fungal effector binds plant,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12567,PHI:8556,UniProt,O52658,GenBank,AE004613_3,,,PAO1,Acp1 (PA1869),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,acyl carrier protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30294316,PubMed,10.3389/fmicb.2018.02244,Front Microbiol. 2018 Sep 20;9:2244,davies@musc.edu,"Deletion of acp3 from P. aeruginosa strain PAO1 resulted in thicker biofilm formation, increased resistance of the strain to hydrogen peroxide, and higher persistence in a mouse infection model.",W Chen 2018,2018,2 genes,Chen-2018-Acyl Carrier Protein 3 Is Involved i,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12568,PHI:8557,UniProt,Q9HYR1,GenBank,AE004755_9,,,PAO1,Acp3 (PA3334),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,acyl carrier protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30294316,PubMed,10.3389/fmicb.2018.02244,Front Microbiol. 2018 Sep 20;9:2244,davies@musc.edu,"Deletion of acp3 from P. aeruginosa strain PAO1 resulted in thicker biofilm formation, increased resistance of the strain to hydrogen peroxide, and higher persistence in a mouse infection model.",W Chen 2018,2018,2 genes,Chen-2018-Acyl Carrier Protein 3 Is Involved i,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12569,PHI:8556,UniProt,O52658,GenBank,AE004613_3,,,PAO1,Acp1 (PA1869),,,,,,PHI:8557,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,acyl carrier protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30294316,PubMed,10.3389/fmicb.2018.02244,Front Microbiol. 2018 Sep 20;9:2244,davies@musc.edu,"Deletion of acp3 from P. aeruginosa strain PAO1 resulted in thicker biofilm formation, increased resistance of the strain to hydrogen peroxide, and higher persistence in a mouse infection model.",W Chen 2018,2018,2 genes,Chen-2018-Acyl Carrier Protein 3 Is Involved i,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12570,PHI:8557,UniProt,Q9HYR1,GenBank,AE004755_9,,,PAO1,Acp3 (PA3334),,,,,,PHI:8556,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,acyl carrier protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30294316,PubMed,10.3389/fmicb.2018.02244,Front Microbiol. 2018 Sep 20;9:2244,davies@musc.edu,"Deletion of acp3 from P. aeruginosa strain PAO1 resulted in thicker biofilm formation, increased resistance of the strain to hydrogen peroxide, and higher persistence in a mouse infection model.",W Chen 2018,2018,2 genes,Chen-2018-Acyl Carrier Protein 3 Is Involved i,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12571,PHI:8558,UniProt,T1YC56,GenBank,AGU62228,,,CN1,Rho,,,,,,,1280,Staphylococcus aureus,,HG001,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,bicyclomycin,bicyclomycin: CHEBI:60584,,,,,gene mutation; gene complementation,,,YVS,30228237,PubMed,10.1128/mBio.01332-18,MBio. 2018 Sep 18;9(5). pii: e01332-18,ulrike.maeder@uni-greifswald.de,A significant decrease in the survival rate was observed when mice were infected with the mutant compared to the parental strain.,A nagel 2018,2018,1 gene,Nagel-2018-Inhibition of Rho Activity Increase,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12572,PHI:8559,UniProt,G2X5W3,GenBank,EGY14454,,,VdLs.17,SOM1 (VDAG_JR2_Chr1g09120a),chromosome 2,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,root,nuclear transcription factor,,,,loss of pathogenicity,,,yes,,,reduced,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30290010,PubMed,10.1111/nph.15514,New Phytol. 2018 Oct 5,gbraus@gwdg.de,SOM1 and VTA3 deletion strains were impaired in their ability to propagate on the root surface.,T T Bui 2018,2018,2 genes,Bui-2018-Verticillium dahliae transcription fa,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12573,PHI:8560,,no data found,,,,,,VTA3 (VDAG_Chr1g07600a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,root,nuclear transcription factor,,,,loss of pathogenicity,,,no,,,reduced,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30290010,PubMed,10.1111/nph.15514,New Phytol. 2018 Oct 5,gbraus@gwdg.de,SOM1 and VTA3 deletion strains were impaired in their ability to propagate on the root surface.,T T Bui 2018,2018,2 genes,Bui-2018-Verticillium dahliae transcription fa,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12574,PHI:8559,UniProt,G2X5W3,GenBank,EGY14454,,,VdLs.17,SOM1 (VDAG_JR2_Chr1g09120a),chromosome 2,,,,,PHI:8560,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,root,nuclear transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,30290010,PubMed,10.1111/nph.15514,New Phytol. 2018 Oct 5,gbraus@gwdg.de,VTA3 overexpression could not rescue developmental defects caused by the SOM1 deletion.,T T Bui 2018,2018,2 genes,Bui-2018-Verticillium dahliae transcription fa,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12575,PHI:8560,,no data found,,,,,,VTA3 (VDAG_Chr1g07600a),,,,,,PHI:8559,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,root,nuclear transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30290010,PubMed,10.1111/nph.15514,New Phytol. 2018 Oct 5,gbraus@gwdg.de,VTA3 overexpression could not rescue developmental defects caused by the SOM1 deletion.,T T Bui 2018,2018,2 genes,Bui-2018-Verticillium dahliae transcription fa,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12576,PHI:8561,UniProt,Q99ZA6,GenBank,AAK34156,,,SF370,dltA (M5005_Spy_1073),,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,infection,primates,9606,Homo sapiens (related: human),,,,serum,putative D-alanine-D-alanyl carrier protein ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30321240,PubMed,10.1371/journal.ppat.1007348,PLoS Pathog. 2018 Oct 15;14(10):e1007348,nsorge3@umcutrecht.nl,"Both ΔsrtAand ΔdltA bacteria remained more susceptible to hGIIA-mediated killing in serum, whereas the ΔlytR and ΔgacI mutants were equally resistant as WT GAS.",V P Van Hensbergen 2018,2018,4 genes,van Hensbergen-2018-Streptococcal Lancefield p,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12577,PHI:8562,UniProt,P0C0H9,GenBank,AAK33966,,,SF370,srtA,,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,infection,primates,9606,Homo sapiens (related: human),,,,serum,sortase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30321240,PubMed,10.1371/journal.ppat.1007348,PLoS Pathog. 2018 Oct 15;14(10):e1007348,nsorge3@umcutrecht.nl,"Both ΔsrtAand ΔdltA bacteria remained more susceptible to hGIIA-mediated killing in serum, whereas the ΔlytR and ΔgacI mutants were equally resistant as WT GAS.",V P Van Hensbergen 2018,2018,4 genes,van Hensbergen-2018-Streptococcal Lancefield p,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12578,PHI:8563,UniProt,J7M8M0,GenBank,BAM30870,,,M1 476,lytR (M5005_Spy_1474),chromosome 1,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,infection,primates,9606,Homo sapiens (related: human),,,,serum,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30321240,PubMed,10.1371/journal.ppat.1007348,PLoS Pathog. 2018 Oct 15;14(10):e1007348,nsorge3@umcutrecht.nl,"Both ΔsrtAand ΔdltA bacteria remained more susceptible to hGIIA-mediated killing in serum, whereas the ΔlytR and ΔgacI mutants were equally resistant as WT GAS.",V P Van Hensbergen 2018,2018,4 genes,van Hensbergen-2018-Streptococcal Lancefield p,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12579,PHI:8564,UniProt,J7M7C2,GenBank,BAM30000,,,M1 476,gacI (M5005_Spy_0609),,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,infection,primates,9606,Homo sapiens (related: human),,,,serum,phosphoglycerol transferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30321240,PubMed,10.1371/journal.ppat.1007348,PLoS Pathog. 2018 Oct 15;14(10):e1007348,nsorge3@umcutrecht.nl,"Both ΔsrtAand ΔdltA bacteria remained more susceptible to hGIIA-mediated killing in serum, whereas the ΔlytR and ΔgacI mutants were equally resistant as WT GAS.",V P Van Hensbergen 2018,2018,4 genes,van Hensbergen-2018-Streptococcal Lancefield p,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12580,PHI:8565,UniProt,E0SBG4,GenBank,ADM99568,,,3937,gcpA (Dda3937_03858),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,The ΔrsmC and ΔgcpA mutants overgrew the wild type strain.,K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12581,PHI:8566,UniProt,E0SLU4,GenBank,ADM96928,,,3937,rsmC (Dda3937_02456),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,global regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,The ΔrsmC and ΔgcpA mutants overgrew the wild type strain.,K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12582,PHI:8567,UniProt,E0SLG2,GenBank,ADN00484,,,3937,hdfR (Dda3937_04419),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,DNA-binding transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12583,PHI:8568,UniProt,E0SMW8,GenBank,ADM98238,,,3937,clpS,,,,,,PHI:8569,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,ATP-dependent Clp protease adapter protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12584,PHI:8569,UniProt,E0SMW9,GenBank,ADM98239,,,3937,clpA (Dda3937_02363),,,,,,PHI:8568,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,ATP-dependent Clp protease ATP-binding subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12585,PHI:8570,UniProt,E0SGC8,GenBank,ADM96414,,,3937,metB (Dda3937_03888),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,cystathionine gamma-synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12586,PHI:8571,UniProt,E0SIN0,GenBank,ADM99089,,,3937,flhD,,,,,,PHI:8572,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,flagellar transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12587,PHI:8572,UniProt,E0SIM9,GenBank,ADM99088,,,3937,flhC (Dda3937_02784),,,,,,PHI:8571,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,flagellar transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12588,PHI:8573,UniProt,E0SL85,GenBank,ADM99297,,,3937,purF (Dda3937_02099),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,amidophosphoribosyl transferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12589,PHI:8574,UniProt,E0SDK2,GenBank,ADM99812,,,3937,cysJ (Dda3937_00209),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,sulfite reductase alpha subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12590,PHI:8575,UniProt,E0SHD8,GenBank,ADM96537,,,3937,degQ (Dda3937_00697),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12591,PHI:8576,UniProt,E0SLM3,GenBank,ADN00545,,,3937,pyrE (Dda3937_03258),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,orotate phosphoribosyl transferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12592,PHI:8577,UniProt,E0SH08,GenBank,ADN00101,,,3937,carA (Dda3937_01390),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,carbamoyl-phosphate synthase small subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12593,PHI:8578,UniProt,E0SG93,GenBank,ADN00061,,,3937,leuA (Dda3937_04301),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,2-isopropylmalate synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12594,PHI:8579,UniProt,E0SN64,GenBank,ADM99510,,,3937,guaB (Dda3937_00004),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,IMP dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12595,PHI:8580,UniProt,E0SB00,GenBank,ADM99559,,,3937,purL (Dda3937_03379),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,phosphoribosylformyl-glycineamide synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12596,PHI:8581,UniProt,E0SEI0,GenBank,ADM99914,,,3937,lysA (Dda3937_02577),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,diamiopimelate decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30267562,PubMed,10.1111/mpp.12754,Mol Plant Pathol. 2018 Sep 29,erwan.gueguen@univ-lyon1.fr,"The wild type strain overgrew the other in frame deletion mutants that were tested and the lowest competitive indexes were observed with the mutants in biosynthetic pathways such as ΔleuA, ΔguaB, ΔpurL, ΔlysA.",K Royet 2018,2018,17 genes,Royet-2018-Identification by Tn-seq of Dickeya,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12597,PHI:8582,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,508771,type II strain ME49,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30301855,PubMed,10.1128/mBio.01738-18,MBio. 2018 Oct 9;9(5). pii: e01738-18,myamamoto@biken.osaka-u.ac.jp,IL-1beta production occurred in THP-1 cells infected with wild-type but not in THP-1 cells infected with GRA15-KO parasites.,H Bando 2018,2018,1 gene,Bando-2018-Inducible Nitric Oxide Synthase Is,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12598,PHI:8582,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,508771,type II strain ME49,toxoplasmosis,primates,9606,Homo sapiens (related: human),Huh-7 cell line,,,hepatocyte,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30301855,PubMed,10.1128/mBio.01738-18,MBio. 2018 Oct 9;9(5). pii: e01738-18,myamamoto@biken.osaka-u.ac.jp,IL-1 negatively regulates the IFN-gamma induced anti-T. gondii response in the Huh7 hepatocyte line.,H Bando 2018,2018,1 gene,Bando-2018-Inducible Nitric Oxide Synthase Is,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12599,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12600,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12601,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,endocarditis specific antigen,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12602,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12603,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12604,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12605,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12606,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,endocarditis specific antigen,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12607,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8583; PHI:8584; PHI:8585,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12608,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12609,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12610,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,endocarditis specific antigen,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12611,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12612,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12613,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12614,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12615,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12616,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12617,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12618,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12619,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12620,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12621,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,endocarditis specific antigen,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12622,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12623,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12624,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12625,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12626,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12627,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12628,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12629,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12630,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12631,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,heart; spleen,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12632,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12633,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12634,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,endocarditis specific antigen,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12635,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12636,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12637,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12638,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12639,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12640,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8583; PHI:8584; PHI:8585,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12641,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12642,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12643,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12644,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12645,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12646,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12647,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12648,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12649,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12650,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12651,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12652,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12653,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12654,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12655,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12656,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12657,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12658,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12659,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12660,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12661,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,endocarditis specific antigen,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12662,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12663,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12664,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12665,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,manganese/zinc transport system ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12666,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,endocarditis specific antigen,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12667,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8583; PHI:8584; PHI:8585,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12668,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12669,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12670,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12671,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12672,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12673,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12674,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12675,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12676,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,divalent metal cation transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12677,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12678,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12679,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12680,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8583; PHI:8584; PHI:8585,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12681,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12682,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12683,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12684,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12685,PHI:8583,,no data found,GenBank,ADX80648,,,C386,efaC,,,,,,PHI:8584; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12686,PHI:8584,,no data found,GenBank,ADX80647,,,62,efaB,,,,,,PHI:8583; PHI:8585; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,manganese/zinc transport system ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12687,PHI:8585,UniProt,Q47723,GenBank,AAA70056,,,,efaA,,,,,,PHI:8583; PHI:8584; PHI:8586; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,endocarditis specific antigen,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12688,PHI:8586,UniProt,A0A1B4XMK3,GenBank,AQL53186,,,CLB21560,mntH1,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8587,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12689,PHI:8587,UniProt,A0A2R6UD96,GenBank,PTN77979,,,B2535,mntH2,,,,,,PHI:8583; PHI:8584; PHI:8585; PHI:8586,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,divalent metal cation transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30235334,PubMed,10.1371/journal.ppat.1007102,PLoS Pathog. 2018 Sep 20;14(9):e1007102,jlemos@dental.ufl.edu,"The simultaneous inactivation of EfaCBA, MntH1 and MntH2 (ΔefaΔmntH1ΔmntH2 strain) led to drastic reductions in cellular Mn content.",C Colomer-Winter,2018,5 genes,Colomer-Winter-2018-Manganese acquisition is e,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12690,PHI:8588,UniProt,G4NH84,GenBank,EHA47594,,,70-15,Moppe1,chromosome 6,,,MoSap1; MoMkk1,UniProt: G4N8M9; GenBank: EHA50223; UniProt: G4N6Z7; GenBank: EHA50760,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,serine/threonine-protein phosphatase,,,cell wall integrity (CWI) signalling pathway,reduced virulence,,no,yes,yes,,wild type,,reduced,reduced,no,calcofluor white (CFW); Congo red (CR),calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30246284,PubMed,10.1111/1462-2920.14421,Environ Microbiol. 2018 Sep 24,zhgzhang@njau.edu.cn,"MoPpe1 was required for vegetative growth, conidiation and full virulence.",B Qian 2018,2018,1 gene,Qian-2018-MoPpe1 partner with MoSap1 to mediat,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12691,PHI:8588,UniProt,G4NH84,GenBank,EHA47594,,,70-15,Moppe1,chromosome 6,,,MoSap1; MoMkk1,UniProt: G4N8M9; GenBank: EHA50223; UniProt: G4N6Z7; GenBank: EHA50760,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,serine/threonine-protein phosphatase,,,cell wall integrity (CWI) signalling pathway,reduced virulence,,,,,,wild type,,reduced,reduced,no,calcofluor white (CFW); Congo red (CR),calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30246284,PubMed,10.1111/1462-2920.14421,Environ Microbiol. 2018 Sep 24,zhgzhang@njau.edu.cn,"MoPpe1 was required for vegetative growth, conidiation and full virulence.",B Qian 2018,2018,1 gene,Qian-2018-MoPpe1 partner with MoSap1 to mediat,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12692,PHI:8589,UniProt,Q18BV2,GenBank,CAJ68295,,,630,PdaA1 (CD630_14300 ),,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,putative delta-lactam-biosynthetic de-N-acteylase,,,,reduced virulence,,,,,,reduced; aberrant,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30266804,PubMed,10.1074/jbc.RA118.004273,J Biol Chem. 2018 Sep 28. pii: jbc.RA118.004273,Thomas.candela@u-psud.fr,"PdaA1 was the major N-deacetylase for muramic-δ-lactam biosynthesis in C. difficile, contributing to sporulation, heat resistance and virulence.",H Coullon 2018,2018,1 gene,Coullon-2018-N-Deacetylases required for muram,BATCH_087B,2018-11-01,MC,,,,,,,,,,,,,
,,Record 12693,PHI:8590,UniProt,Q4WGN8,GenBank,EAL86903,,,Af293,met8 (AFUA_7G05680),chromosome 7,,,,,,746128,Aspergillus fumigatus,,AfS77,aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,siroheme synthase,,,siroheme biosynthetic pathway,reduced virulence,,,,,,,,wild type,,no,sodium nitrite,sodium nitrite: CHEBI:78870,,,,,gene deletion: full; gene complementation,,,YVS,30483221,PubMed,10.3389/fmicb.2018.02615,Front Microbiol. 2018 Nov 12;9:2615,hubertus.haas@i-med.ac.at,Met8-deficiency caused significantly decreased resistance against nitric oxide (NO) underlining the importance of nitrite reductase in NO detoxification.,A M Dietl 2018,2018,1 gene,Dietl-2018-Siroheme Is Essential for Assimilat,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12694,PHI:8590,UniProt,Q4WGN8,GenBank,EAL86903,,,Af293,met8 (AFUA_7G05680),chromosome 7,,,,,,746128,Aspergillus fumigatus,,AfS77,aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,siroheme synthase,,,siroheme biosynthetic pathway,unaffected pathogenicity,,,,,,,,wild type,,no,sodium nitrite,sodium nitrite: CHEBI:78870,,,,,gene deletion: full; gene complementation,,,YVS,30483221,PubMed,10.3389/fmicb.2018.02615,Front Microbiol. 2018 Nov 12;9:2615,hubertus.haas@i-med.ac.at,Met8-deficiency did not affect virulence in murine models for invasive aspergillosis indicating that neither NO-detoxification nor assimilation of sulfate and nitrate played major roles in virulence in this host.,A M Dietl 2018,2018,1 gene,Dietl-2018-Siroheme Is Essential for Assimilat,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12695,PHI:8591,UniProt,J9VUM7,GenBank,AFR98177,,,H99,Rcv1 (CNAG_01983),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung,Wor1-like transcription factor,,,,reduced virulence,no,,,,,,,reduced,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30483479,PubMed,10.3389/fcimb.2018.00369,Front Cell Infect Microbiol. 2018 Nov 13;8:369,lfernandesmatos@gmail.com,"The Δrcv1 strain was completely avirulent at 37°C and hypovirulent at 30°C relative to wild-type, indicating that virulence loss in this mutant was only partially explained by a defect in adaptation to the temperatures of the mammalian host.",H C Paes 2018,2018,1 gene,Paes-2018-A Wor1-Like Transcription Factor Is,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12696,PHI:8591,UniProt,J9VUM7,GenBank,AFR98177,,,H99,Rcv1 (CNAG_01983),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Wor1-like transcription factor,,,,reduced virulence,no,,,,,,,reduced,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30483479,PubMed,10.3389/fcimb.2018.00369,Front Cell Infect Microbiol. 2018 Nov 13;8:369,lfernandesmatos@gmail.com,"The Δrcv1 strain was completely avirulent at 37°C and hypovirulent at 30°C relative to wild-type, indicating that virulence loss in this mutant was only partially explained by a defect in adaptation to the temperatures of the mammalian host.",H C Paes 2018,2018,1 gene,Paes-2018-A Wor1-Like Transcription Factor Is,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12697,PHI:8591,UniProt,J9VUM7,GenBank,AFR98177,,,H99,Rcv1 (CNAG_01983),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,Wor1-like transcription factor,,,,reduced virulence,no,,,,,,,reduced,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30483479,PubMed,10.3389/fcimb.2018.00369,Front Cell Infect Microbiol. 2018 Nov 13;8:369,lfernandesmatos@gmail.com,"The Δrcv1 strain was completely avirulent at 37°C and hypovirulent at 30°C relative to wild-type, indicating that virulence loss in this mutant was only partially explained by a defect in adaptation to the temperatures of the mammalian host.",H C Paes 2018,2018,1 gene,Paes-2018-A Wor1-Like Transcription Factor Is,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12698,PHI:8592,UniProt,F9XNZ8,GenBank,EGP83081,,,IPO323,ZtPpt,chromosome 12,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,phosphopantetheinyl transferase,,,lysine biosynthesis,loss of pathogenicity,,,,,,,,reduced,,no,H2O2; bathophenanthroline disulphate; desferriferrichrome,H2O2: CHEBI:16240; bathophenanthroline disulphate: CHEBI:78158; desferriferrichrome: CHEBI:90132,,,,,gene deletion: full; gene complementation,,,YVS,30459352,PubMed,10.1038/s41598-018-35223-8,Sci Rep. 2018 Nov 20;8(1):17069,jason.rudd@rothamsted.ac.uk,"The ΔZtPpt strains were auxotrophic for lysine and iron, non-melanised and non-pathogenic on wheat.",M C Derbyshire 2018,2018,6 genes,Derbyshire-2018-Phosphopantetheinyl transferas,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12699,PHI:8593,UniProt,F9XMW3,GenBank,EGP83620,,,IPO323,ZtPks1,chromosome 11,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,melanin synthetase,,,DHN-melanin biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; bathophenanthroline disulphate; desferriferrichrome,H2O2: CHEBI:16240; bathophenanthroline disulphate: CHEBI:78158; desferriferrichrome: CHEBI:90132,,,,,gene deletion: full; gene complementation,,,YVS,30459352,PubMed,10.1038/s41598-018-35223-8,Sci Rep. 2018 Nov 20;8(1):17069,jason.rudd@rothamsted.ac.uk,"Deletion of the three target genes likely affected by ZtPpt loss of function (Aar- lysine; Nrps1-siderophore and Pks1-melanin), highlighted that lysine auxotrophy was the main contributing factor for loss of virulence, with no reduction caused by loss of siderophore production or melanisation.",M C Derbyshire 2018,2018,6 genes,Derbyshire-2018-Phosphopantetheinyl transferas,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12700,PHI:8594,UniProt,F9X2M4,GenBank,EGP89716,,,IPO323,ZtNrps1,chromosome 2,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,putative non-ribosomal peptide synthetase,,,siderophore biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; bathophenanthroline disulphate; desferriferrichrome,H2O2: CHEBI:16240; bathophenanthroline disulphate: CHEBI:78158; desferriferrichrome: CHEBI:90132,,,,,gene deletion: full; gene complementation,,,YVS,30459352,PubMed,10.1038/s41598-018-35223-8,Sci Rep. 2018 Nov 20;8(1):17069,jason.rudd@rothamsted.ac.uk,"Deletion of the three target genes likely affected by ZtPpt loss of function (Aar- lysine; Nrps1-siderophore and Pks1-melanin), highlighted that lysine auxotrophy was the main contributing factor for loss of virulence, with no reduction caused by loss of siderophore production or melanisation.",M C Derbyshire 2018,2018,6 genes,Derbyshire-2018-Phosphopantetheinyl transferas,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12701,PHI:8595,UniProt,F9X701,GenBank,EGP88909,,,IPO323,ZtAar,chromosome 3,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,alpha aminoadipate reductase,,,lysine biosynthesis,loss of pathogenicity,,,,,,,,reduced,,no,H2O2; bathophenanthroline disulphate; desferriferrichrome,H2O2: CHEBI:16240; bathophenanthroline disulphate: CHEBI:78158; desferriferrichrome: CHEBI:90132,,,,,gene deletion: full; gene complementation,,,YVS,30459352,PubMed,10.1038/s41598-018-35223-8,Sci Rep. 2018 Nov 20;8(1):17069,jason.rudd@rothamsted.ac.uk,"Deletion of the three target genes likely affected by ZtPpt loss of function (Aar- lysine; Nrps1-siderophore and Pks1-melanin), highlighted that lysine auxotrophy was the main contributing factor for loss of virulence, with no reduction caused by loss of siderophore production or melanisation.",M C Derbyshire 2018,2018,6 genes,Derbyshire-2018-Phosphopantetheinyl transferas,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12702,PHI:8592,UniProt,F9XNZ8,GenBank,EGP83081,,,IPO323,ZtPpt,chromosome 12,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu70,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,phosphopantetheinyl transferase,,,lysine biosynthesis,loss of pathogenicity,,,,,,,,reduced,,no,H2O2; bathophenanthroline disulphate; desferriferrichrome,H2O2: CHEBI:16240; bathophenanthroline disulphate: CHEBI:78158; desferriferrichrome: CHEBI:90132,,,,,gene deletion: full; gene complementation,,,YVS,30459352,PubMed,10.1038/s41598-018-35223-8,Sci Rep. 2018 Nov 20;8(1):17069,jason.rudd@rothamsted.ac.uk,"The ΔZtPpt strains were auxotrophic for lysine and iron, non-melanised and non-pathogenic on wheat.",M C Derbyshire 2018,2018,6 genes,Derbyshire-2018-Phosphopantetheinyl transferas,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12703,PHI:8593,UniProt,F9XMW3,GenBank,EGP83620,,,IPO323,ZtPks1,chromosome 11,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu70,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,melanin synthetase,,,DHN-melanin biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; bathophenanthroline disulphate; desferriferrichrome,H2O2: CHEBI:16240; bathophenanthroline disulphate: CHEBI:78158; desferriferrichrome: CHEBI:90132,,,,,gene deletion: full; gene complementation,,,YVS,30459352,PubMed,10.1038/s41598-018-35223-8,Sci Rep. 2018 Nov 20;8(1):17069,jason.rudd@rothamsted.ac.uk,"Deletion of the three target genes likely affected by ZtPpt loss of function (Aar- lysine; Nrps1-siderophore and Pks1-melanin), highlighted that lysine auxotrophy was the main contributing factor for loss of virulence, with no reduction caused by loss of siderophore production or melanisation.",M C Derbyshire 2018,2018,6 genes,Derbyshire-2018-Phosphopantetheinyl transferas,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12704,PHI:8594,UniProt,F9X2M4,GenBank,EGP89716,,,IPO323,ZtNrps1,chromosome 2,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu70,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,putative non-ribosomal peptide synthetase,,,siderophore biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; bathophenanthroline disulphate; desferriferrichrome,H2O2: CHEBI:16240; bathophenanthroline disulphate: CHEBI:78158; desferriferrichrome: CHEBI:90132,,,,,gene deletion: full; gene complementation,,,YVS,30459352,PubMed,10.1038/s41598-018-35223-8,Sci Rep. 2018 Nov 20;8(1):17069,jason.rudd@rothamsted.ac.uk,"Deletion of the three target genes likely affected by ZtPpt loss of function (Aar- lysine; Nrps1-siderophore and Pks1-melanin), highlighted that lysine auxotrophy was the main contributing factor for loss of virulence, with no reduction caused by loss of siderophore production or melanisation.",M C Derbyshire 2018,2018,6 genes,Derbyshire-2018-Phosphopantetheinyl transferas,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12705,PHI:8595,UniProt,F9X701,GenBank,EGP88909,,,IPO323,ZtAar,chromosome 3,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu70,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,alpha aminoadipate reductase,,,lysine biosynthesis,loss of pathogenicity,,,,,,,,reduced,,no,H2O2; bathophenanthroline disulphate; desferriferrichrome,H2O2: CHEBI:16240; bathophenanthroline disulphate: CHEBI:78158; desferriferrichrome: CHEBI:90132,,,,,gene deletion: full; gene complementation,,,YVS,30459352,PubMed,10.1038/s41598-018-35223-8,Sci Rep. 2018 Nov 20;8(1):17069,jason.rudd@rothamsted.ac.uk,"Deletion of the three target genes likely affected by ZtPpt loss of function (Aar- lysine; Nrps1-siderophore and Pks1-melanin), highlighted that lysine auxotrophy was the main contributing factor for loss of virulence, with no reduction caused by loss of siderophore production or melanisation.",M C Derbyshire 2018,2018,6 genes,Derbyshire-2018-Phosphopantetheinyl transferas,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12706,PHI:8596,UniProt,F9XFI6,GenBank,EGP85920,,,IPO323,ZtPks7,chromosome 7,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu70,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,polyketide synthase,,,secondary metabolite biosynthesis,unaffected pathogenicity,,,,,,,,,,no,H2O2; bathophenanthroline disulphate; desferriferrichrome,H2O2: CHEBI:16240; bathophenanthroline disulphate: CHEBI:78158; desferriferrichrome: CHEBI:90132,,,,,gene deletion: full; gene complementation,,,YVS,30459352,PubMed,10.1038/s41598-018-35223-8,Sci Rep. 2018 Nov 20;8(1):17069,jason.rudd@rothamsted.ac.uk,PKS7 gene strongly up-regulated during leaf infection were not required for virulence.,M C Derbyshire 2018,2018,6 genes,Derbyshire-2018-Phosphopantetheinyl transferas,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12707,PHI:8597,UniProt,F9XQ63,GenBank,EGP82707,,,IPO323,ZtPks8,chromosome 13,,,,,,1047171,Zymoseptoria tritici,336722,IPO323 ΔKu70,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,polyketide synthase,,,secondary metabolite biosynthesis,unaffected pathogenicity,,,,,,,,,,no,H2O2; bathophenanthroline disulphate; desferriferrichrome,H2O2: CHEBI:16240; bathophenanthroline disulphate: CHEBI:78158; desferriferrichrome: CHEBI:90132,,,,,gene deletion: full; gene complementation,,,YVS,30459352,PubMed,10.1038/s41598-018-35223-8,Sci Rep. 2018 Nov 20;8(1):17069,jason.rudd@rothamsted.ac.uk,PKS8 gene strongly up-regulated during leaf infection were not required for virulence.,M C Derbyshire 2018,2018,6 genes,Derbyshire-2018-Phosphopantetheinyl transferas,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12708,PHI:8598,UniProt,J9VPD7,GenBank,AFR96118,,,H99,Cda1 (CNAG_05799),chromosome 7,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,lung; brain,chitin deacetylase,,,chitosan biosynthesis pathway,reduced virulence,,,,,,,,wild type,,no,H2O2; sodium nitrite; SDS; NaCl,H2O2: CHEBI:16240; sodium nitrite: CHEBI:78870; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,30459196,PubMed,10.1128/mBio.02087-18,MBio. 2018 Nov 20;9(6). pii: e02087-18,lodgejk@wustl.edu,The mere presence of Cda1 protein was not enough to cause fungal pathogenesis but that its chitin deacetylase enzyme activity was essential for virulence in this model.,R Upadhya 2018,2018,3 genes,Upadhya-2018-Cryptococcus neoformans Cda1 and,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12709,PHI:8598,UniProt,J9VPD7,GenBank,AFR96118,,,H99,Cda1 (CNAG_05799),chromosome 7,"cda1 D166N,R254A,D294N (cda1CS)",,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,lung; brain,chitin deacetylase,,,chitosan biosynthesis pathway,reduced virulence,,,,,,,,wild type,,no,H2O2; sodium nitrite; SDS; NaCl,H2O2: CHEBI:16240; sodium nitrite: CHEBI:78870; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene mutation: characterised,,,YVS,30459196,PubMed,10.1128/mBio.02087-18,MBio. 2018 Nov 20;9(6). pii: e02087-18,lodgejk@wustl.edu,The mere presence of Cda1 protein was not enough to cause fungal pathogenesis but that its chitin deacetylase enzyme activity was essential for virulence in this model.,R Upadhya 2018,2018,3 genes,Upadhya-2018-Cryptococcus neoformans Cda1 and,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12710,PHI:8599,UniProt,J9VND2,GenBank,AFR94916,,,H99,Cda2 (CNAG_01230),chromosome 5,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,lung; brain,chitin deacetylase,,,chitosan biosynthesis pathway,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; sodium nitrite; SDS; NaCl,H2O2: CHEBI:16240; sodium nitrite: CHEBI:78870; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,30459196,PubMed,10.1128/mBio.02087-18,MBio. 2018 Nov 20;9(6). pii: e02087-18,lodgejk@wustl.edu,The mere presence of Cda1 protein was not enough to cause fungal pathogenesis but that its chitin deacetylase enzyme activity was essential for virulence in this model.,R Upadhya 2018,2018,3 genes,Upadhya-2018-Cryptococcus neoformans Cda1 and,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12711,PHI:8600,UniProt,P82476,GenBank,AFR94907,,,H99,Cda3 (CNAG_01239),chromosome 5,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,lung; brain,chitin deacetylase,,,chitosan biosynthesis pathway,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; sodium nitrite; SDS; NaCl,H2O2: CHEBI:16240; sodium nitrite: CHEBI:78870; SDS: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,30459196,PubMed,10.1128/mBio.02087-18,MBio. 2018 Nov 20;9(6). pii: e02087-18,lodgejk@wustl.edu,The mere presence of Cda1 protein was not enough to cause fungal pathogenesis but that its chitin deacetylase enzyme activity was essential for virulence in this model.,R Upadhya 2018,2018,3 genes,Upadhya-2018-Cryptococcus neoformans Cda1 and,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12712,PHI:8601,UniProt,Q4WV27,GenBank,EAL91549,,,Af293,cofilin (AFUA_5G10570),chromosome 5,cofilin teton,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,actin depolymerizing factor,,,cell wall integrity pathway,reduced virulence,,,,,,,,reduced,,no,H2O2; SDS; calcofluor white; Congo red; farnesol,H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; farnesol: CHEBI:28600,,,,,promoter mutation,,,YVS,30455681,PubMed,10.3389/fmicb.2018.02667,Front Microbiol. 2018 Nov 2;9:2667,hanlicdc@163.com,"Repressing cofilin expression in A. fumigatus lead to attenuated virulence, which manifested as lower adherence and internalization rates.",X jia 2018,2018,1 gene,Jia-2018-Role of Downregulation and Phosphoryl,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12713,PHI:8601,UniProt,Q4WV27,GenBank,EAL91549,,,Af293,cofilin (AFUA_5G10570),chromosome 5,cofilin teton/cofilinS5E,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,actin depolymerizing factor,,,cell wall integrity pathway,reduced virulence,,,,,,,,reduced,,no,H2O2; SDS; calcofluor white; Congo red; farnesol,H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; farnesol: CHEBI:28600,,,,,promoter mutation,,,YVS,30455681,PubMed,10.3389/fmicb.2018.02667,Front Microbiol. 2018 Nov 2;9:2667,hanlicdc@163.com,"Expression of non-phosphorylated cofilin with a mutation of S5A had little impacts on A. fumigatus, whereas expression of a mimic-phosphorylated cofilin with a mutation of S5E resulted in inhibited growth, increased phospho-MpkA level, and decreased pathogenicity.",X jia 2018,2018,1 gene,Jia-2018-Role of Downregulation and Phosphoryl,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12714,PHI:8601,UniProt,Q4WV27,GenBank,EAL91549,,,Af293,cofilin (AFUA_5G10570),chromosome 5,cofilinS5A,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,actin depolymerizing factor,,,cell wall integrity pathway,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; SDS; calcofluor white; Congo red; farnesol,H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; farnesol: CHEBI:28600,,,,,gene mutation: characterised,,,YVS,30455681,PubMed,10.3389/fmicb.2018.02667,Front Microbiol. 2018 Nov 2;9:2667,hanlicdc@163.com,"Expression of non-phosphorylated cofilin with a mutation of S5A had little impacts on A. fumigatus, whereas expression of a mimic-phosphorylated cofilin with a mutation of S5E resulted in inhibited growth, increased phospho-MpkA level, and decreased pathogenicity.",X jia 2018,2018,1 gene,Jia-2018-Role of Downregulation and Phosphoryl,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12715,PHI:8601,UniProt,Q4WV27,GenBank,EAL91549,,,Af293,cofilin (AFUA_5G10570),chromosome 5,cofilinS5A,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,actin depolymerizing factor,,,cell wall integrity pathway,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; SDS; calcofluor white; Congo red; farnesol,H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; farnesol: CHEBI:28600,,,,,gene mutation: characterised,,,YVS,30455681,PubMed,10.3389/fmicb.2018.02667,Front Microbiol. 2018 Nov 2;9:2667,hanlicdc@163.com,"Expression of non-phosphorylated cofilin with a mutation of S5A had little impacts on A. fumigatus, whereas expression of a mimic-phosphorylated cofilin with a mutation of S5E resulted in inhibited growth, increased phospho-MpkA level, and decreased pathogenicity.",X jia 2018,2018,1 gene,Jia-2018-Role of Downregulation and Phosphoryl,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12716,PHI:8601,UniProt,Q4WV27,GenBank,EAL91549,,,Af293,cofilin (AFUA_5G10570),chromosome 5,cofilin teton,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,actin depolymerizing factor,,,cell wall integrity pathway,reduced virulence,,,,,,,,reduced,,no,H2O2; SDS; calcofluor white; Congo red; farnesol,H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; farnesol: CHEBI:28600,,,,,promoter mutation,,,YVS,30455681,PubMed,10.3389/fmicb.2018.02667,Front Microbiol. 2018 Nov 2;9:2667,hanlicdc@163.com,"Repressing cofilin expression in A. fumigatus lead to attenuated virulence, which manifested as weaker host inflammatory response and shorter survival rate in a Galleria mellonella model.",X jia 2018,2018,1 gene,Jia-2018-Role of Downregulation and Phosphoryl,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12717,PHI:8601,UniProt,Q4WV27,GenBank,EAL91549,,,Af293,cofilin (AFUA_5G10570),chromosome 5,cofilin teton/cofilinS5E,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,actin depolymerizing factor,,,cell wall integrity pathway,reduced virulence,,,,,,,,reduced,,no,H2O2; SDS; calcofluor white; Congo red; farnesol,H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; farnesol: CHEBI:28600,,,,,promoter mutation,,,YVS,30455681,PubMed,10.3389/fmicb.2018.02667,Front Microbiol. 2018 Nov 2;9:2667,hanlicdc@163.com,"Expression of non-phosphorylated cofilin with a mutation of S5A had little impacts on A. fumigatus, whereas expression of a mimic-phosphorylated cofilin with a mutation of S5E resulted in inhibited growth, increased phospho-MpkA level, and decreased pathogenicity.",X jia 2018,2018,1 gene,Jia-2018-Role of Downregulation and Phosphoryl,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12718,PHI:8602,UniProt,A7EP87,GenBank,EDO04653,,,1980,SsSte12 (SS1G_07136),,,,SsMcm1,UniProt: A7EJU3; GenBank: EDO03109,,5180,Sclerotinia sclerotiorum,,UF1,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,transcription regulator,,,mitogen-activated protein kinase (MAPK) pathway,reduced virulence,,,yes,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30386319,PubMed,10.3389/fmicb.2018.02476,Front Microbiol. 2018 Oct 17;9:2476,yh_zhang@jlu.edu.cn,"Silencing SsSte12 in S.sclerotiorum resulted in phenotypes of delayed vegetative growth, reduced size of sclerotia, and fewer appressoria formation.",T Xu 2018,2018,1 gene,Xu-2018-Transcription Factor SsSte12 Was Invol,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12719,PHI:8602,UniProt,A7EP87,GenBank,EDO04653,,,1980,SsSte12 (SS1G_07136),,,,SsMcm1,UniProt: A7EJU3; GenBank: EDO03109,,5180,Sclerotinia sclerotiorum,,UF1,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,transcription regulator,,,mitogen-activated protein kinase (MAPK) pathway,reduced virulence,,,yes,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30386319,PubMed,10.3389/fmicb.2018.02476,Front Microbiol. 2018 Oct 17;9:2476,yh_zhang@jlu.edu.cn,"Silencing SsSte12 in S.sclerotiorum resulted in phenotypes of delayed vegetative growth, reduced size of sclerotia, and fewer appressoria formation.",T Xu 2018,2018,1 gene,Xu-2018-Transcription Factor SsSte12 Was Invol,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12720,PHI:8603,UniProt,Q10896,GenBank,CCP42826,,,H37Rv,nrp (Rv0101),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,nonribosomal peptide synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30381350,PubMed,10.1128/mSphere.00352-18,mSphere. 2018 Oct 31;3(5). pii: e00352-18,margarida.saraiva@ibmc.up.pt,"The nrp mutant was highly attenuated in immunodeficient (SCID-, recombination activating 2 [RAG2]-, and gamma interferon [IFN-gamma]-deficient) mice, suggesting that macrophages controlled the nrp mutant more effciently than they controlled the wild-type strain.",K Bhatt 2018,2018,1 gene,Bhatt-2018-A Nonribosomal Peptide Synthase Gen,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12721,PHI:8603,UniProt,Q10896,GenBank,CCP42826,,,H37Rv,nrp (Rv0101),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,nonribosomal peptide synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30381350,PubMed,10.1128/mSphere.00352-18,mSphere. 2018 Oct 31;3(5). pii: e00352-18,margarida.saraiva@ibmc.up.pt,"The nrp mutant was highly attenuated in immunodeficient (SCID-, recombination activating 2 [RAG2]-, and gamma interferon [IFN-gamma]-deficient) mice, suggesting that macrophages controlled the nrp mutant more effciently than they controlled the wild-type strain.",K Bhatt 2018,2018,1 gene,Bhatt-2018-A Nonribosomal Peptide Synthase Gen,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12722,PHI:8603,UniProt,Q10896,GenBank,CCP42826,,,H37Rv,nrp (Rv0101),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,peritoneal cavity,nonribosomal peptide synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30381350,PubMed,10.1128/mSphere.00352-18,mSphere. 2018 Oct 31;3(5). pii: e00352-18,margarida.saraiva@ibmc.up.pt,"The nrp mutant was highly attenuated in immunodeficient (SCID-, recombination activating 2 [RAG2]-, and gamma interferon [IFN-gamma]-deficient) mice, suggesting that macrophages controlled the nrp mutant more effciently than they controlled the wild-type strain.",K Bhatt 2018,2018,1 gene,Bhatt-2018-A Nonribosomal Peptide Synthase Gen,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12723,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,E281A,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),,,,skin,virulence sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12724,PHI:8605,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovR,,D53A,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),,,,skin,virulence regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12725,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,T284A,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),,,,skin,virulence sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12726,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,E281A,,,,,1314,Streptococcus pyogenes,530008,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),,,,skin,virulence sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12727,PHI:8605,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovR,,D53A,,,,,1314,Streptococcus pyogenes,530008,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),,,,skin,virulence regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12728,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,T284A,,,,,1314,Streptococcus pyogenes,530008,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),,,,skin,virulence sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12729,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,E281A,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),,,,nasopharynx,virulence sensor kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12730,PHI:8605,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovR,,D53A,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),,,,nasopharynx,virulence regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12731,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,T284A,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),,,,nasopharynx,virulence sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12732,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,E281A,,,,,1314,Streptococcus pyogenes,530008,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),,,,nasopharynx,virulence sensor kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12733,PHI:8605,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovR,,D53A,,,,,1314,Streptococcus pyogenes,530008,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),,,,nasopharynx,virulence regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12734,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,T284A,,,,,1314,Streptococcus pyogenes,530008,MGAS2221,infection,rodents,10090,Mus musculus (related: house mouse),,,,nasopharynx,virulence sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12735,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,E281A,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,primates,9606,Homo sapiens (related: human),,,,blood,virulence sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12736,PHI:8605,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovR,,D53A,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,primates,9606,Homo sapiens (related: human),,,,blood,virulence regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12737,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,T284A,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,primates,9606,Homo sapiens (related: human),,,,blood,virulence sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12738,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,E281A,,,,,1314,Streptococcus pyogenes,530008,MGAS2221,infection,primates,9606,Homo sapiens (related: human),,,,blood,virulence sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12739,PHI:8605,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovR,,D53A,,,,,1314,Streptococcus pyogenes,530008,MGAS2221,infection,primates,9606,Homo sapiens (related: human),,,,blood,virulence regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12740,PHI:8604,UniProt,D4QE70,GenBank,AFO38406,,,N38,CovS,,T284A,,,,,1314,Streptococcus pyogenes,530008,MGAS2221,infection,primates,9606,Homo sapiens (related: human),,,,blood,virulence sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,30379939,PubMed,10.1371/journal.ppat.1007354,PLoS Pathog. 2018 Oct 31;14(10):e1007354,sshelburne@manderson.org,"In both serotypes, GAS strains lacking CovS phosphatase activity (CovS-T284A) were profoundly impaired in their ability to cause skin infectionor colonize the oropharynx in mice and to survive neutrophil killing in human blood.",N Horstmann 2018,2018,2 genes,Horstmann-2018-Phosphatase activity of the con,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12741,PHI:8606,UniProt,A0A384JRT5,GenBank,ATZ53308,,,B05.10,BcXyl1,BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,xylanase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30405585,PubMed,10.3389/fmicb.2018.02535,Front Microbiol. 2018 Oct 23;9:2535,qiudewen@caas.cn,"BcXyl1 induced strong cell death in several plants, and cell death activity of BcXyl1 was independent of its xylanase activity.",Y Yang 2018,2018,1 gene,Yang-2018-The Botrytis cinerea Xylanase BcXyl1,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12742,PHI:8606,UniProt,A0A384JRT5,GenBank,ATZ53308,,,B05.10,BcXyl1,BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,xylanase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30405585,PubMed,10.3389/fmicb.2018.02535,Front Microbiol. 2018 Oct 23;9:2535,qiudewen@caas.cn,"BcXyl1 induced strong cell death in several plants, and cell death activity of BcXyl1 was independent of its xylanase activity.",Y Yang 2018,2018,1 gene,Yang-2018-The Botrytis cinerea Xylanase BcXyl1,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12743,PHI:8606,UniProt,A0A384JRT5,GenBank,ATZ53308,,,B05.10,BcXyl1,BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,xylanase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30405585,PubMed,10.3389/fmicb.2018.02535,Front Microbiol. 2018 Oct 23;9:2535,qiudewen@caas.cn,"BcXyl1 induced strong cell death in several plants, and cell death activity of BcXyl1 was independent of its xylanase activity.",Y Yang 2018,2018,1 gene,Yang-2018-The Botrytis cinerea Xylanase BcXyl1,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12744,PHI:8606,UniProt,A0A384JRT5,GenBank,ATZ53308,,,B05.10,BcXyl1,BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,xylanase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30405585,PubMed,10.3389/fmicb.2018.02535,Front Microbiol. 2018 Oct 23;9:2535,qiudewen@caas.cn,"BcXyl1 induced strong cell death in several plants, and cell death activity of BcXyl1 was independent of its xylanase activity.",Y Yang 2018,2018,1 gene,Yang-2018-The Botrytis cinerea Xylanase BcXyl1,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12745,PHI:8607,,no data found,,,,,,CgMCK1,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,seed plants,28977,Cunninghamia lanceolata (related: china fir),,,,leaf,MAPKKK protein,,,mitogen-activated protein kinase (MAPK) signaling pathway,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced,reduced,no,NaCl; SDS; calcofluor white; Congo red; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30413120,PubMed,10.3390/genes9110543,Genes (Basel). 2018 Nov 8;9(11). pii: E543,lhuang@njfu.edu.cn,ΔCgmck1 mutant was more sensitive to antagonistic bacterial Bacillus velezensis and similar result was observed in the ΔCgmck1 and the ΔCgmps1 mutants.,Y L Fang 2018,2018,3 genes,Fang-2018-The MAPKKK CgMck1 Is Required for Ce,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12746,PHI:8607,,no data found,,,,,,CgMCK1,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,eudicots,3690,Populus x canadensis (related: carolina poplar),cv. Nanlin 895,,,leaf,MAPKKK protein,,,mitogen-activated protein kinase (MAPK) signaling pathway,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced,reduced,no,NaCl; SDS; calcofluor white; Congo red; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30413120,PubMed,10.3390/genes9110543,Genes (Basel). 2018 Nov 8;9(11). pii: E543,lhuang@njfu.edu.cn,ΔCgmck1 mutant was more sensitive to antagonistic bacterial Bacillus velezensis and similar result was observed in the ΔCgmck1 and the ΔCgmps1 mutants.,Y L Fang 2018,2018,3 genes,Fang-2018-The MAPKKK CgMck1 Is Required for Ce,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12747,PHI:8608,,no data found,,,,,,CgMKK1,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,seed plants,28977,Cunninghamia lanceolata (related: china fir),,,,leaf,MAPKK protein,,,mitogen-activated protein kinase (MAPK) signaling pathway,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced,reduced,no,NaCl; SDS; calcofluor white; Congo red; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30413120,PubMed,10.3390/genes9110543,Genes (Basel). 2018 Nov 8;9(11). pii: E543,lhuang@njfu.edu.cn,ΔCgmck1 mutant was more sensitive to antagonistic bacterial Bacillus velezensis and similar result was observed in the ΔCgmck1 and the ΔCgmps1 mutants.,Y L Fang 2018,2018,3 genes,Fang-2018-The MAPKKK CgMck1 Is Required for Ce,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12748,PHI:8608,,no data found,,,,,,CgMKK1,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,eudicots,3690,Populus x canadensis (related: carolina poplar),cv. Nanlin 895,,,leaf,MAPKK protein,,,mitogen-activated protein kinase (MAPK) signaling pathway,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced,reduced,no,NaCl; SDS; calcofluor white; Congo red; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30413120,PubMed,10.3390/genes9110543,Genes (Basel). 2018 Nov 8;9(11). pii: E543,lhuang@njfu.edu.cn,ΔCgmck1 mutant was more sensitive to antagonistic bacterial Bacillus velezensis and similar result was observed in the ΔCgmck1 and the ΔCgmps1 mutants.,Y L Fang 2018,2018,3 genes,Fang-2018-The MAPKKK CgMck1 Is Required for Ce,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12749,PHI:8609,,no data found,,,,,,CgMPS1,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,seed plants,28977,Cunninghamia lanceolata (related: china fir),,,,leaf,MAPK protein,,,mitogen-activated protein kinase (MAPK) signaling pathway,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced,reduced,no,NaCl; SDS; calcofluor white; Congo red; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30413120,PubMed,10.3390/genes9110543,Genes (Basel). 2018 Nov 8;9(11). pii: E543,lhuang@njfu.edu.cn,ΔCgmck1 mutant was more sensitive to antagonistic bacterial Bacillus velezensis and similar result was observed in the ΔCgmck1 and the ΔCgmps1 mutants.,Y L Fang 2018,2018,3 genes,Fang-2018-The MAPKKK CgMck1 Is Required for Ce,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12750,PHI:8609,,no data found,,,,,,CgMPS1,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,eudicots,3690,Populus x canadensis (related: carolina poplar),cv. Nanlin 895,,,leaf,MAPK protein,,,mitogen-activated protein kinase (MAPK) signaling pathway,loss of pathogenicity,,yes,yes,yes,,reduced,,reduced,reduced,no,NaCl; SDS; calcofluor white; Congo red; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30413120,PubMed,10.3390/genes9110543,Genes (Basel). 2018 Nov 8;9(11). pii: E543,lhuang@njfu.edu.cn,ΔCgmck1 mutant was more sensitive to antagonistic bacterial Bacillus velezensis and similar result was observed in the ΔCgmck1 and the ΔCgmps1 mutants.,Y L Fang 2018,2018,3 genes,Fang-2018-The MAPKKK CgMck1 Is Required for Ce,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12751,PHI:8610,UniProt,G4N6S1,GenBank,EHA49888,,,70-15,gcn5 (MGG_03677),chromosome 4,,,pyruvate kinase,UniProt: G4MXS1; GenBank: EHA55208,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,histone acetyltransferase,,,,reduced virulence,,,,,,increased,,,,no,,,,,,,gene deletion: full,,,YVS,30505942,PubMed,10.1128/mSystems.00270-18,mSystems. 2018 Nov 20;3(6). pii: e00270-18,dengyz@scau.edu.cn,Regulation of Pk turnover via acetylation and autophagic degradation contributed to proper conidiation and host infection.,M Liang 2018,2018,3 genes,Liang-2018-Label-Free Quantitative Proteomics,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12752,PHI:8611,UniProt,G4MXS1,GenBank,EHA55208,,,70-15,pyruvate kinase,chromosome 2,,,gcn5 (MGG_03677),UniProt: G4N6S1; GenBank: EHA49888,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,pyruvate kinase,,,,unaffected pathogenicity,,no,,,,wild type,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30505942,PubMed,10.1128/mSystems.00270-18,mSystems. 2018 Nov 20;3(6). pii: e00270-18,dengyz@scau.edu.cn,Regulation of Pk turnover via acetylation and autophagic degradation contributed to proper conidiation and host infection.,M Liang 2018,2018,3 genes,Liang-2018-Label-Free Quantitative Proteomics,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12753,PHI:8611,UniProt,G4MXS1,GenBank,EHA55208,,,70-15,pyruvate kinase,chromosome 2,K188R,,gcn5 (MGG_03677),UniProt: G4N6S1; GenBank: EHA49888,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,pyruvate kinase,,,,reduced virulence,,no,,,,wild type,,,,no,,,,,,,gene mutation; altered gene expression / gene regulation: overexpression,,,YVS,30505942,PubMed,10.1128/mSystems.00270-18,mSystems. 2018 Nov 20;3(6). pii: e00270-18,dengyz@scau.edu.cn,Regulation of Pk turnover via acetylation and autophagic degradation contributed to proper conidiation and host infection.,M Liang 2018,2018,3 genes,Liang-2018-Label-Free Quantitative Proteomics,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12754,PHI:8611,UniProt,G4MXS1,GenBank,EHA55208,,,70-15,pyruvate kinase,chromosome 2,K188Q,,gcn5 (MGG_03677),UniProt: G4N6S1; GenBank: EHA49888,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,pyruvate kinase,,,,unaffected pathogenicity,,no,,,,increased,,,,no,,,,,,,gene mutation; altered gene expression / gene regulation: overexpression,,,YVS,30505942,PubMed,10.1128/mSystems.00270-18,mSystems. 2018 Nov 20;3(6). pii: e00270-18,dengyz@scau.edu.cn,Regulation of Pk turnover via acetylation and autophagic degradation contributed to proper conidiation and host infection.,M Liang 2018,2018,3 genes,Liang-2018-Label-Free Quantitative Proteomics,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12755,PHI:8611,UniProt,G4MXS1,GenBank,EHA55208,,,70-15,pyruvate kinase,chromosome 2,K188R,,gcn5 (MGG_03677),UniProt: G4N6S1; GenBank: EHA49888,PHI:8610,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,pyruvate kinase,,,,reduced virulence,,,,,,increased,,,,no,,,,,,,gene mutation; altered gene expression / gene regulation: overexpression,,,YVS,30505942,PubMed,10.1128/mSystems.00270-18,mSystems. 2018 Nov 20;3(6). pii: e00270-18,dengyz@scau.edu.cn,Regulation of Pk turnover via acetylation and autophagic degradation contributed to proper conidiation and host infection.,M Liang 2018,2018,3 genes,Liang-2018-Label-Free Quantitative Proteomics,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12756,PHI:8610,UniProt,G4N6S1,GenBank,EHA49888,,,70-15,gcn5 (MGG_03677),chromosome 4,,,pyruvate kinase,UniProt: G4MXS1; GenBank: EHA55208,PHI:8611,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,histone acetyltransferase,,,,reduced virulence,,,,,,increased,,,,no,,,,,,,gene deletion: full,,,YVS,30505942,PubMed,10.1128/mSystems.00270-18,mSystems. 2018 Nov 20;3(6). pii: e00270-18,dengyz@scau.edu.cn,Regulation of Pk turnover via acetylation and autophagic degradation contributed to proper conidiation and host infection.,M Liang 2018,2018,3 genes,Liang-2018-Label-Free Quantitative Proteomics,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12757,PHI:8611,UniProt,G4MXS1,GenBank,EHA55208,,,70-15,pyruvate kinase,chromosome 2,K188Q,,gcn5 (MGG_03677),UniProt: G4N6S1; GenBank: EHA49888,PHI:8610,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,pyruvate kinase,,,,unaffected pathogenicity,,,,,,wild type,,,,no,,,,,,,gene mutation; altered gene expression / gene regulation: overexpression,,,YVS,30505942,PubMed,10.1128/mSystems.00270-18,mSystems. 2018 Nov 20;3(6). pii: e00270-18,dengyz@scau.edu.cn,Regulation of Pk turnover via acetylation and autophagic degradation contributed to proper conidiation and host infection.,M Liang 2018,2018,3 genes,Liang-2018-Label-Free Quantitative Proteomics,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12758,PHI:8610,UniProt,G4N6S1,GenBank,EHA49888,,,70-15,gcn5 (MGG_03677),chromosome 4,,,pyruvate kinase,UniProt: G4MXS1; GenBank: EHA55208,PHI:8611,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,histone acetyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,,,no,,,,,,,gene deletion: full,,,YVS,30505942,PubMed,10.1128/mSystems.00270-18,mSystems. 2018 Nov 20;3(6). pii: e00270-18,dengyz@scau.edu.cn,Regulation of Pk turnover via acetylation and autophagic degradation contributed to proper conidiation and host infection.,M Liang 2018,2018,3 genes,Liang-2018-Label-Free Quantitative Proteomics,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12759,PHI:8611,UniProt,G4MXS1,GenBank,EHA55208,,,70-15,pyruvate kinase,chromosome 2,K188Q,,gcn5 (MGG_03677),UniProt: G4N6S1; GenBank: EHA49888,PHI:8612,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,pyruvate kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; altered gene expression / gene regulation: overexpression,,,YVS,30505942,PubMed,10.1128/mSystems.00270-18,mSystems. 2018 Nov 20;3(6). pii: e00270-18,dengyz@scau.edu.cn,Regulation of Pk turnover via acetylation and autophagic degradation contributed to proper conidiation and host infection.,M Liang 2018,2018,3 genes,Liang-2018-Label-Free Quantitative Proteomics,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12760,PHI:8612,UniProt,Q52EB3,GenBank,EHA50859,,,70-15,atg 1,chromosome 4,,,,,PHI:8611,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,serine/threonine-protein kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30505942,PubMed,10.1128/mSystems.00270-18,mSystems. 2018 Nov 20;3(6). pii: e00270-18,dengyz@scau.edu.cn,Regulation of Pk turnover via acetylation and autophagic degradation contributed to proper conidiation and host infection.,M Liang 2018,2018,3 genes,Liang-2018-Label-Free Quantitative Proteomics,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12761,PHI:8613,UniProt,A0A0H3PEF7,GenBank,EAQ73062,,,81-176,tlp2 (Cjj81176_0180),,,,,,,197,Campylobacter jejuni,,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,intestine-407 cell,methyl-accepting chemotaxis protein/ transducer-like protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,CuCl2; FeSO4; FeCl3; MnCl2; ZnCl2,CuCl2: CHEBI:49553; FeSO4: CHEBI:75832; FeCl3: CHEBI:30808; MnCl2: CHEBI:63041; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,30505293,PubMed,10.3389/fmicb.2018.02674,Front Microbiol. 2018 Nov 16;9:2674,rajashekara.2@osu.edu,"The tlp2 deletion mutant showed decreased chemotaxis toward aspartate, pyruvate, inorganic phosphate (Pi), and iron (FeSO4).",K Chandrashekhar 2018,2018,1 gene,Chandrashekhar-2018-Transducer-Like Protein in,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12762,PHI:8613,UniProt,A0A0H3PEF7,GenBank,EAQ73062,,,81-176,tlp2 (Cjj81176_0180),,,,,,,197,Campylobacter jejuni,,81-176,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,cecum; duodenum; jejunum,methyl-accepting chemotaxis protein/ transducer-like protein,,,,reduced virulence,,,,,,,,reduced,,no,CuCl2; FeSO4; FeCl3; MnCl2; ZnCl2,CuCl2: CHEBI:49553; FeSO4: CHEBI:75832; FeCl3: CHEBI:30808; MnCl2: CHEBI:63041; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,30505293,PubMed,10.3389/fmicb.2018.02674,Front Microbiol. 2018 Nov 16;9:2674,rajashekara.2@osu.edu,"The tlp2 deletion mutant showed decreased chemotaxis toward aspartate, pyruvate, inorganic phosphate (Pi), and iron (FeSO4).",K Chandrashekhar 2018,2018,1 gene,Chandrashekhar-2018-Transducer-Like Protein in,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12763,PHI:8613,UniProt,A0A0H3PEF7,GenBank,EAQ73062,,,81-176,tlp2 (Cjj81176_0180),,,,,,,197,Campylobacter jejuni,,81-176,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen; bursa of Fabricius,methyl-accepting chemotaxis protein/ transducer-like protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,CuCl2; FeSO4; FeCl3; MnCl2; ZnCl2,CuCl2: CHEBI:49553; FeSO4: CHEBI:75832; FeCl3: CHEBI:30808; MnCl2: CHEBI:63041; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,30505293,PubMed,10.3389/fmicb.2018.02674,Front Microbiol. 2018 Nov 16;9:2674,rajashekara.2@osu.edu,"The tlp2 deletion mutant showed decreased chemotaxis toward aspartate, pyruvate, inorganic phosphate (Pi), and iron (FeSO4).",K Chandrashekhar 2018,2018,1 gene,Chandrashekhar-2018-Transducer-Like Protein in,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12764,PHI:8614,UniProt,P65946,GenBank,AAK75382,,,TIGR4,pyrR (SP_1278),,mutation that interferes with the binding of PyrR to the pyr mRNA,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),,,,blood; lung; nasopharynx,RNA cis-regulator,,,,loss of pathogenicity,,,,,,,,reduced,,no,5-fluoroorotic acid,5-fluoroorotic acid: CHEBI:74498,,,,,gene mutation,,,YVS,30517198,PubMed,10.1371/journal.ppat.1007461,PLoS Pathog. 2018 Dec 5;14(12):e1007461,vanopijn@bc.edu,Regulation by the pyrR RNA element was crucial for in vivo survival and virulence of S. pneumoniae.,I Warrier 2018,2018,1 gene,Warrier-2018-The Transcriptional landscape of,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12765,PHI:8614,UniProt,P65946,GenBank,AAK75382,,,TIGR4,pyrR (SP_1278),,"mutation that renders the regulatory element in an ""always on"" state by destabilizing the rho-independent terminator stem-loop structure that is formed in the presence of UMP",,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),,,,blood; nasopharynx,RNA cis-regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,5-fluoroorotic acid,5-fluoroorotic acid: CHEBI:74498,,,,,gene mutation,,,YVS,30517198,PubMed,10.1371/journal.ppat.1007461,PLoS Pathog. 2018 Dec 5;14(12):e1007461,vanopijn@bc.edu,Regulation by the pyrR RNA element was crucial for in vivo survival and virulence of S. pneumoniae.,I Warrier 2018,2018,1 gene,Warrier-2018-The Transcriptional landscape of,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12766,PHI:8614,UniProt,P65946,GenBank,AAK75382,,,TIGR4,pyrR (SP_1278),,"mutation that renders the regulatory element in an ""always on"" state by destabilizing the rho-independent terminator stem-loop structure that is formed in the presence of UMP",,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),,,,lung,RNA cis-regulator,,,,reduced virulence,,,,,,,,wild type,,no,5-fluoroorotic acid,5-fluoroorotic acid: CHEBI:74498,,,,,gene mutation,,,YVS,30517198,PubMed,10.1371/journal.ppat.1007461,PLoS Pathog. 2018 Dec 5;14(12):e1007461,vanopijn@bc.edu,Regulation by the pyrR RNA element was crucial for in vivo survival and virulence of S. pneumoniae.,I Warrier 2018,2018,1 gene,Warrier-2018-The Transcriptional landscape of,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12767,PHI:8614,UniProt,P65946,GenBank,AAK75382,,,TIGR4,pyrR (SP_1278),,"mutation that locks the terminator and creates an ""always off"" state",,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),,,,blood; lung; nasopharynx,RNA cis-regulator,,,,loss of pathogenicity,,,,,,,,reduced,,no,5-fluoroorotic acid,5-fluoroorotic acid: CHEBI:74498,,,,,gene mutation,,,YVS,30517198,PubMed,10.1371/journal.ppat.1007461,PLoS Pathog. 2018 Dec 5;14(12):e1007461,vanopijn@bc.edu,Regulation by the pyrR RNA element was crucial for in vivo survival and virulence of S. pneumoniae.,I Warrier 2018,2018,1 gene,Warrier-2018-The Transcriptional landscape of,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12768,PHI:8615,UniProt,J9VHR2,GenBank,AFR93743,,,H99,Grx4 (CNAG_02950),chromosome 3,mutant lacking the sequence encoding the C-terminal 157-amino acid region containing the GRX domain,,cir1 (CNAG_04864),UniProt: J9VSB5; GenBank: AFR97352,,5207,Cryptococcus neoformans,235443,H99,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung; spleen,monothiol glutaredoxin,,,heme biosynthesis,loss of pathogenicity,,,,,,,,reduced,,no,"curcumin; ferrozine; FeCl3; FeSO4; heme; chloroquine; CoCl2; phleomycin; rotenone; malonic acid; antimycin A; potassium cyanide [KCN]; salicylic hydroxamate [SHAM]; diphenyleneiodonium [DPI]; t-BOOH; H2O2; 1-chloro-2,4-dinitrobenzene [CDNB]; plumbagin; menadione; paraquat; methyl methanesulfonate; hydroxyurea","curcumin: CHEBI:3962; ferrozine: CAS:32796-55-7; FeCl3: CHEBI:30808; FeSO4: CHEBI:75832; heme: CHEBI:30413; chloroquine: CHEBI:3638; CoCl2: CHEBI:35696; phleomycin,  rotenone: CHEBI:28201; malonic acid: CHEBI:30794; salicylhydroxamic acid (SHAM): CHEBI:45615; antimycin A: CHEBI:22584; potassium cyanide (KCN): CHEBI:33191; hydrogen peroxide (H2O2): CHEBI:16240; paraquat: CHEBI:34905; plumbagin: CHEBI:8273; diphenyleneiodonium chloride (DPI): CHEBI:77967; menadione: CHEBI:28869; t-BOOH: CHEBI:64090; 1-chloro-2,4-dinitrobenzene [CDNB]: CHEBI:34718; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255",,,,,gene deletion: partial; gene complementation,,,YVS,30514787,PubMed,10.1128/mBio.02377-18,MBio. 2018 Dec 4;9(6). pii: e02377-18,kronstad@msl.ubc.ca,"The grx4 mutant was avirulent in mice, a phenotype consistent with observed defects in the key virulence determinants, capsule and melanin, and poor growth at 37°C.",R Attarian 2018,2018,1 gene,Attarian-2018-The Monothiol Glutaredoxin Grx4,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12769,PHI:8616,UniProt,B4EPZ1,GenBank,CAR57157,,,J2315,ShvR (BCAS0225),chromosome 3,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30513124,PubMed,10.1371/journal.ppat.1007473,PLoS Pathog. 2018 Dec 4;14(12):e1007473,annette.vergunst@umontpellier.fr,"Shvr was required for the induction of fatal proinflammatory responses in zebrafish larvae, but was not essential for bacterial survival and replication in macrophages.",MC Gomes 2018,2018,3 genes,Gomes-2018-The afc antifungal activity cluster,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12770,PHI:8617,UniProt,B4EPX4,GenBank,CAR57140,,,J2315,afcE (BCAS0208),chromosome 3,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,acyl-CoA dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30513124,PubMed,10.1371/journal.ppat.1007473,PLoS Pathog. 2018 Dec 4;14(12):e1007473,annette.vergunst@umontpellier.fr,AfcE was critical for the switch from intracellular persistence to fatal infection in zebrafish.,MC Gomes 2018,2018,3 genes,Gomes-2018-The afc antifungal activity cluster,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12771,PHI:8616,UniProt,B4EPZ1,GenBank,CAR57157,,,J2315,ShvR (BCAS0225),chromosome 3,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,LysR-type transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30513124,PubMed,10.1371/journal.ppat.1007473,PLoS Pathog. 2018 Dec 4;14(12):e1007473,annette.vergunst@umontpellier.fr,"Shvr was required for the induction of fatal proinflammatory responses in zebrafish larvae, but was not essential for bacterial survival and replication in macrophages.",MC Gomes 2018,2018,3 genes,Gomes-2018-The afc antifungal activity cluster,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12772,PHI:8616,UniProt,B4EPZ1,GenBank,CAR57157,,,J2315,ShvR (BCAS0225),chromosome 3,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,LysR-type transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30513124,PubMed,10.1371/journal.ppat.1007473,PLoS Pathog. 2018 Dec 4;14(12):e1007473,annette.vergunst@umontpellier.fr,"Shvr was required for the induction of fatal proinflammatory responses in zebrafish larvae, but was not essential for bacterial survival and replication in macrophages.",MC Gomes 2018,2018,3 genes,Gomes-2018-The afc antifungal activity cluster,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12773,PHI:8618,,no data found,,,,,,afc,,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,acyl-CoA dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: cluster,,,YVS,30513124,PubMed,10.1371/journal.ppat.1007473,PLoS Pathog. 2018 Dec 4;14(12):e1007473,annette.vergunst@umontpellier.fr,Acute virulence of H111 depended on the presence of the afc cluster.,MC Gomes 2018,2018,3 genes,Gomes-2018-The afc antifungal activity cluster,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12774,PHI:8616,UniProt,B4EPZ1,GenBank,CAR57157,,,J2315,ShvR (BCAS0225),chromosome 3,,,,,PHI:8618,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30513124,PubMed,10.1371/journal.ppat.1007473,PLoS Pathog. 2018 Dec 4;14(12):e1007473,annette.vergunst@umontpellier.fr,"Shvr was required for the induction of fatal proinflammatory responses in zebrafish larvae, but was not essential for bacterial survival and replication in macrophages.",MC Gomes 2018,2018,3 genes,Gomes-2018-The afc antifungal activity cluster,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12775,PHI:8618,,no data found,,,,,,afc,,,,,,PHI:8616,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,acyl-CoA dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: cluster,,,YVS,30513124,PubMed,10.1371/journal.ppat.1007473,PLoS Pathog. 2018 Dec 4;14(12):e1007473,annette.vergunst@umontpellier.fr,Acute virulence of H111 depended on the presence of the afc cluster.,MC Gomes 2018,2018,3 genes,Gomes-2018-The afc antifungal activity cluster,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12776,PHI:8619,UniProt,Q663K1,GenBank,CAA36129,,,"YPIII/pIB1, serotype III",YopN,,"yopN GAGA mutant, where the putative CCD motif is disrupted encompassing aa 80–86",,,,,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; mesenteric lymph node,outer membrane protein involved in regulation and activation of the T3SS,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30488778,PubMed,10.1080/21505594.2018.1551709,Virulence. 2019 Dec;10(1):10-25,ake.forsberg@molbiol.umu.se,The yopN GAGA cis mutant was impaired for YopH and YopE translocation and was attenuated in the systemic mouse infection model.,S Bamyaci 2019,2019,1 gene,Bamyaci-2019-Identification of specific sequen,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12777,PHI:8620,UniProt,Q8E1M5,GenBank,AE014206_15,,,2603V/R,cel-EIIB (SAG0329),,,,,,,1311,Streptococcus agalactiae,,THN0901,neonatal pneumonia; neonatal meningitis; bovine mastitis; meningoencephalitis (fish),bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,blood; brain; liver; spleen,"phosphoenolpyruvate (PEP)-dependent sugar phosphotransferase system (PTS), cellobiose-specific IIB component",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30374993,PubMed,10.1111/jfd.12907,J Fish Dis. 2019 Jan;42(1):11-19,lianxing@mail.sysu.edu.cn,The cellobiose utilization and biofilm formation ability of Δcel-EIIB strain was significantly decreased relative to S.a.THN0901 strain.,J Xu 2019,2019,1 gene,Xu-2019-Virulence regulation of cel-EIIB prote,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12778,PHI:8621,UniProt,Q9K035,GenBank,AAF41200,,,MC58,cbp (NMB0787),,,,,,,487,Neisseria meningitidis,,NIID84 Δcps,septicemia,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,cysteine-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; H2O2; paraquat,NaCl: CHEBI:26710; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene disruption; gene complementation,,,YVS,30538184,PubMed,10.1128/mBio.02332-18,MBio. 2018 Dec 11;9(6). pii: e02332-18,hideyuki@nih.go.jp.,"N. meningitidis strain deficient in cbp exhibited approximately 100-fold less internalization into human brain microvascular endothelial cells (HBMEC) than the wild-type strain and this deficiency was restored by complementation with the three cts genes (cysteine-binding protein (cbp), cysteine transporter permease (ctp), and cysteine ATP-binding protein (cab)) together.",H Takahashi 2018,2018,4 genes,Takahashi-2018-The Meningococcal Cysteine Tran,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12779,PHI:8621,UniProt,Q9K035,GenBank,AAF41200,,,MC58,cbp (NMB0787),,,,,,,487,Neisseria meningitidis,,NIID84 Δcps,septicemia,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,cysteine-binding protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,NaCl; H2O2; paraquat,NaCl: CHEBI:26710; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,other evidence: ectopic complementation,,,YVS,30538184,PubMed,10.1128/mBio.02332-18,MBio. 2018 Dec 11;9(6). pii: e02332-18,hideyuki@nih.go.jp.,"N. meningitidis strain deficient in cbp exhibited approximately 100-fold less internalization into human brain microvascular endothelial cells (HBMEC) than the wild-type strain and this deficiency was restored by complementation with the three cts genes (cysteine-binding protein (cbp), cysteine transporter permease (ctp), and cysteine ATP-binding protein (cab)) together.",H Takahashi 2018,2018,4 genes,Takahashi-2018-The Meningococcal Cysteine Tran,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12780,PHI:8622,UniProt,Q9K034,GenBank,AAF41201,,,MC58,ctp (NMB0788),,,,,,,487,Neisseria meningitidis,,NIID84 Δcps,septicemia,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,cysteine transporter permease,,,,unaffected pathogenicity,,,,,,,,reduced,,no,NaCl; H2O2; paraquat,NaCl: CHEBI:26710; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,other evidence: ectopic complementation,,,YVS,30538184,PubMed,10.1128/mBio.02332-18,MBio. 2018 Dec 11;9(6). pii: e02332-18,hideyuki@nih.go.jp.,"N. meningitidis strain deficient in cbp exhibited approximately 100-fold less internalization into human brain microvascular endothelial cells (HBMEC) than the wild-type strain and this deficiency was restored by complementation with the three cts genes (cysteine-binding protein (cbp), cysteine transporter permease (ctp), and cysteine ATP-binding protein (cab)) together.",H Takahashi 2018,2018,4 genes,Takahashi-2018-The Meningococcal Cysteine Tran,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12781,PHI:8623,UniProt,Q9K033,GenBank,AAF41202,,,MC58,cab (NMB0789),,,,,,,487,Neisseria meningitidis,,NIID84 Δcps,septicemia,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,cysteine ATP binding protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,NaCl; H2O2; paraquat,NaCl: CHEBI:26710; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,other evidence: ectopic complementation,,,YVS,30538184,PubMed,10.1128/mBio.02332-18,MBio. 2018 Dec 11;9(6). pii: e02332-18,hideyuki@nih.go.jp.,"N. meningitidis strain deficient in cbp exhibited approximately 100-fold less internalization into human brain microvascular endothelial cells (HBMEC) than the wild-type strain and this deficiency was restored by complementation with the three cts genes (cysteine-binding protein (cbp), cysteine transporter permease (ctp), and cysteine ATP-binding protein (cab)) together.",H Takahashi 2018,2018,4 genes,Takahashi-2018-The Meningococcal Cysteine Tran,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12782,PHI:8624,UniProt,Q9JYJ3,GenBank,AAF41913,,,MC58,ghsb,,,,,,,487,Neisseria meningitidis,,NIID84 Δcps,septicemia,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,glutathione synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,NaCl; H2O2; paraquat,NaCl: CHEBI:26710; H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,30538184,PubMed,10.1128/mBio.02332-18,MBio. 2018 Dec 11;9(6). pii: e02332-18,hideyuki@nih.go.jp.,"N. meningitidis strain deficient in cbp exhibited approximately 100-fold less internalization into human brain microvascular endothelial cells (HBMEC) than the wild-type strain and this deficiency was restored by complementation with the three cts genes (cysteine-binding protein (cbp), cysteine transporter permease (ctp), and cysteine ATP-binding protein (cab)) together.",H Takahashi 2018,2018,4 genes,Takahashi-2018-The Meningococcal Cysteine Tran,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12783,PHI:8625,UniProt,Q8I6Z5,GenBank,CAD52383,,,3D7,pfpmv,chromosome 13,the region of the pfpmv gene encoding Asp133 to Thr590 was replaced with two loxP-containing P. falciparum SERA2 introns flanking a recodonised pfpmv gene,,,,,5833,Plasmodium falciparum,36329,3D7,malaria,primates,9606,Homo sapiens (related: human),,,,erythrocyte,aspartic protease,,,plasmodium protein export pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,YVS,30517136,PubMed,10.1371/journal.pone.0207621,PLoS One. 2018 Dec 5;13(12):e0207621,mike.blackman@crick.ac.uk,Functional disruption of PfPMV resulted in developmental arrest at the ring-to-trophozoite transition.,N Boonyalai 2018,2018,1 gene,Boonyalai-2018-Essentiality of Plasmodium falc,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12784,PHI:8626,UniProt,D2TI12,GenBank,CBG90789,,,ICC168,EspO,,,,,,,67825,Citrobacter rodentium,637910,ICC169,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colonic epithelial cell,putative T3SS effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30365535,PubMed,10.1371/journal.ppat.1007406,PLoS Pathog. 2018 Oct 26;14(10):e1007406,g.frankel@imperial.ac.uk,Infection with ΔespO was characterized by diminished recruitment of sub-mucosal neutrophils and triggered significantly lesser nutritional immunity and expression of antimicrobial peptides compared to mice infected with WT C. rodentium.,C N Berger 2018,2018,1 gene,Berger-2018-The Citrobacter rodentium type III,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12785,PHI:8627,UniProt,O52908,GenBank,CAL34238,,,NCTC 11168,flhF,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,campylobacteriosis; gastroenteritis,birds,9031,Gallus gallus (related: chicken),Leghorn,,,cecum; colon; duodenum; jejunum; ileum,flagellar biosynthesis protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30348090,PubMed,10.1186/s12866-018-1318-1,BMC Microbiol. 2018 Oct 22;18(1):149,jiao@yzu.edu.cn,"Adhesion, invasion, autoagglutination and biofilm-formation abilities of the flhF mutant strain were significantly decreased.",F Ren 2018,2018,1 gene,Ren-2018-Insights into the impact of flhF inac,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12786,PHI:8627,UniProt,O52908,GenBank,CAL34238,,,NCTC 11168,flhF,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,campylobacteriosis; gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon; duodenum; jejunum; ileum,flagellar biosynthesis protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30348090,PubMed,10.1186/s12866-018-1318-1,BMC Microbiol. 2018 Oct 22;18(1):149,jiao@yzu.edu.cn,"Adhesion, invasion, autoagglutination and biofilm-formation abilities of the flhF mutant strain were significantly decreased.",F Ren 2018,2018,1 gene,Ren-2018-Insights into the impact of flhF inac,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12787,PHI:8627,UniProt,O52908,GenBank,CAL34238,,,NCTC 11168,flhF,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,campylobacteriosis; gastroenteritis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,flagellar biosynthesis protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30348090,PubMed,10.1186/s12866-018-1318-1,BMC Microbiol. 2018 Oct 22;18(1):149,jiao@yzu.edu.cn,"Adhesion, invasion, autoagglutination and biofilm-formation abilities of the flhF mutant strain were significantly decreased.",F Ren 2018,2018,1 gene,Ren-2018-Insights into the impact of flhF inac,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12788,PHI:8628,UniProt,X0J1D8,GenBank,EXL90176,,,54006,SIX1a (FOIG_16557),,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense TR4 strain II5,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),cv. Grand Nain,,,leaf; root,small secreted fungal protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30346962,PubMed,10.1371/journal.pone.0205896,PLoS One. 2018 Oct 22;13(10):e0205896,m.rep@uva.nl,SIX1a was required for full virulence of Focub II5 in banana.,S Widinugraheni 2018,2018,1 gene,Widinugraheni-2018-A SIX1 homolog in Fusarium,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12789,PHI:8629,UniProt,G4N7U7,GenBank,EHA50901,,,70-15,MoAbp1 (MGG_06358),chromosome 4,,,MoCap1 (MGG_01722); MoArk1 (MGG_11326); MoAct1,UniProt: G4MV90; GenBank: EHA54912; UniProt: G4MV67; GenBank: EHA54082; UniProt: no data fou,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,actin-binding protein,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30451565,PubMed,10.1094/MPMI-10-18-0281-R,Mol Plant Microbe Interact. 2018 Nov 19,zhgzhang@njau.edu.cn,"The ΔMoabp1 mutant exhibited delayed endocytosis and defects in the growth, host penetration and invasive growth.",L Li 2018,2018,1 gene,"Li-2018-Magnaporthe oryzae Abp1, a MoArk1 kina",BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12790,PHI:8629,UniProt,G4N7U7,GenBank,EHA50901,,,70-15,MoAbp1 (MGG_06358),chromosome 4,,,MoCap1 (MGG_01722); MoArk1 (MGG_11326); MoAct1,UniProt: G4MV90; GenBank: EHA54912; UniProt: G4MV67; GenBank: EHA54082; UniProt: no data fou,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,actin-binding protein,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30451565,PubMed,10.1094/MPMI-10-18-0281-R,Mol Plant Microbe Interact. 2018 Nov 19,zhgzhang@njau.edu.cn,"The ΔMoabp1 mutant exhibited delayed endocytosis and defects in the growth, host penetration and invasive growth.",L Li 2018,2018,1 gene,"Li-2018-Magnaporthe oryzae Abp1, a MoArk1 kina",BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12791,PHI:8630,UniProt,J4W5V1,GenBank,EJP65725,,,ARSEF 2860,creA,,,,,,,176275,Beauveria bassiana,,Bb2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,carbon catabolite repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30443979,PubMed,10.1002/ps.5266,Pest Manag Sci. 2018 Nov 16,yulongwa@mtu.edu,The pathogenicity of creA and fkh2 deletion strains on G. mellonella and P. xylostella were attenuated.,Q Zhou 2018,2018,2 genes,Zhou-2018-In vivo transcriptomic analysis of B,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12792,PHI:8631,UniProt,J4VW09,GenBank,EJP62625,,,ARSEF 2860,fkh2,,,,,,,176275,Beauveria bassiana,,Bb2860,white muscardine,moths,51655,Plutella xylostella (related: diamondback moth),,,,larva,"transcription factor, fork head",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30443979,PubMed,10.1002/ps.5266,Pest Manag Sci. 2018 Nov 16,yulongwa@mtu.edu,The pathogenicity of creA and fkh2 deletion strains on G. mellonella and P. xylostella were attenuated.,Q Zhou 2018,2018,2 genes,Zhou-2018-In vivo transcriptomic analysis of B,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12793,PHI:8630,UniProt,J4W5V1,GenBank,EJP65725,,,ARSEF 2860,creA,,,,,,,176275,Beauveria bassiana,,Bb2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,carbon catabolite repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30443979,PubMed,10.1002/ps.5266,Pest Manag Sci. 2018 Nov 16,yulongwa@mtu.edu,The pathogenicity of creA and fkh2 deletion strains on G. mellonella and P. xylostella were attenuated.,Q Zhou 2018,2018,2 genes,Zhou-2018-In vivo transcriptomic analysis of B,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12794,PHI:8631,UniProt,J4VW09,GenBank,EJP62625,,,ARSEF 2860,fkh2,,,,,,,176275,Beauveria bassiana,,Bb2860,white muscardine,moths,51655,Plutella xylostella (related: diamondback moth),,,,larva,"transcription factor, fork head",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30443979,PubMed,10.1002/ps.5266,Pest Manag Sci. 2018 Nov 16,yulongwa@mtu.edu,The pathogenicity of creA and fkh2 deletion strains on G. mellonella and P. xylostella were attenuated.,Q Zhou 2018,2018,2 genes,Zhou-2018-In vivo transcriptomic analysis of B,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12795,PHI:8632,,no data found,,,,,,zmp,,,,,,,1307,Streptococcus suis,218494,P1/7,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,bronchial epithelial cell line,zinc metalloprotease,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30373658,PubMed,10.1186/s13567-018-0606-y,Vet Res. 2018 Oct 29;49(1):109,marcelo.gottschalk@umontreal.ca,"The absence of a functional Zmp protein did not affect the ability of S. suis to adhere to porcine bronchial epithelial cells in vitro, or to colonize the upper respiratory tract of pigs in vivo.",A Dumesnil 2018,2018,1 gene,Dumesnil-2018-Characterization of the zinc met,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12796,PHI:8632,,no data found,,,,,,zmp,,,,,,,1307,Streptococcus suis,218494,P1/7,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,liver; spleen; brain; tonsil; trachea,zinc metalloprotease,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30373658,PubMed,10.1186/s13567-018-0606-y,Vet Res. 2018 Oct 29;49(1):109,marcelo.gottschalk@umontreal.ca,"The absence of a functional Zmp protein did not affect the ability of S. suis to adhere to porcine bronchial epithelial cells in vitro, or to colonize the upper respiratory tract of pigs in vivo.",A Dumesnil 2018,2018,1 gene,Dumesnil-2018-Characterization of the zinc met,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12797,PHI:8632,,no data found,,,,,,zmp,,,,,,,1307,Streptococcus suis,218494,P1/7,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasal cavity; peritoneal cavity,zinc metalloprotease,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30373658,PubMed,10.1186/s13567-018-0606-y,Vet Res. 2018 Oct 29;49(1):109,marcelo.gottschalk@umontreal.ca,Zmp was not implicated in the virulence of S. suis serotype 2 in mouse model of infection.,A Dumesnil 2018,2018,1 gene,Dumesnil-2018-Characterization of the zinc met,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12798,PHI:8633,UniProt,A0A0H3MFV9,GenBank,CAR17120,,,IAI39,wzy,,,,,,,562,Escherichia coli,,DE17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryonic fibroblast cell line,O-antigen polymerase,,,LPS biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30553014,PubMed,10.1016/j.micpath.2018.12.021,Microb Pathog. 2018 Dec 12;127:296-303,hanxgan@163.com,"The wzy mutation significantly decreased the adherence and invasion to DF-1 cells, especially the survival abilities in duck serum and complement.",J Zuo 2018,2018,1 gene,Zuo-2018-The role of the wzy gene in lipopolys,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12799,PHI:8633,UniProt,A0A0H3MFV9,GenBank,CAR17120,,,IAI39,wzy,,,,,,,562,Escherichia coli,,DE17,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood; liver; spleen; kidney,O-antigen polymerase,,,LPS biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30553014,PubMed,10.1016/j.micpath.2018.12.021,Microb Pathog. 2018 Dec 12;127:296-303,hanxgan@163.com,"The bacterial load in the blood, liver, spleen and kidneys of ducks infected with DE17Δwzy was decreased significantly compared with wild-type strain.",J Zuo 2018,2018,1 gene,Zuo-2018-The role of the wzy gene in lipopolys,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12800,PHI:8634,UniProt,Q4Q597,GenBank,CAJ08705,,,Friedlin,SODB1 (XM_001685449),,,,,,,5664,Leishmania major,347515,MHOM/IL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,macrophage; foot,superoxide dismutase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30372439,PubMed,10.1371/journal.pntd.0006921,PLoS Negl Trop Dis. 2018 Oct 29;12(10):e0006921,thomas.morrison@ucdenver.edu,"The persistence of SODB1/Δsodb1 L. major in WT macrophages was impaired, and the development of cutaneous lesions in SODB1/Δsodb1 L. major-infected C57BL/6 and BALB/c mice was strongly reduced.",B J Davenport 2018,2018,1 gene,Davenport-2018-SODB1 is essential for Leishman,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12801,PHI:8634,UniProt,Q4Q597,GenBank,CAJ08705,,,Friedlin,SODB1 (XM_001685449),,,,,,,5664,Leishmania major,347515,MHOM/IL/80/Friedlin,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,foot,superoxide dismutase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30372439,PubMed,10.1371/journal.pntd.0006921,PLoS Negl Trop Dis. 2018 Oct 29;12(10):e0006921,thomas.morrison@ucdenver.edu,"The persistence of SODB1/Δsodb1 L. major in WT macrophages was impaired, and the development of cutaneous lesions in SODB1/Δsodb1 L. major-infected C57BL/6 and BALB/c mice was strongly reduced.",B J Davenport 2018,2018,1 gene,Davenport-2018-SODB1 is essential for Leishman,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12802,PHI:8635,UniProt,P0C0B3,GenBank,BAA02938,,,Su,arcA/sagp,,,,,,,1314,Streptococcus pyogenes,,M49-16,streptococcal sepsis,rodents,10090,Mus musculus (related: house mouse),(C57BL x CBA)F1,,,subcutaneous tissue; lymph node; blood; spleen; thymus,arginine deiminase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial,,,YVS,30471128,PubMed,10.1111/sji.12734,Scand J Immunol. 2018 Nov 24:e12734,Starickova@yandex.ru,Mice infected with S. pyogenes M49-16 delArcA demonstrated less intensive bacterial growth in the primary foci and less pronounced bacterial dissemination as compared with animals infected with the parental strain.,S E Alexandrovna 2018,2018,1 gene,Starikova-2018-Role of arginine deiminase in t,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12803,PHI:8636,UniProt,A0A0U2P760,GenBank,ALZ72743,,,PXO83,CspA (WP_011258294.1),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,cold-shock protein,,,glucan biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30372574,PubMed,10.1111/mpp.12763,Mol Plant Pathol. 2018 Oct 29,gaoxw@njau.edu.cn,CspA was important for cellular growth at low temperature and for virulence against rice.,L Wu 2018,2018,4 genes,Wu-2018-Contribution of the cold shock protein,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12804,PHI:8637,UniProt,A0A0U4VHH3,GenBank,ALZ72162,,,PXO83,CspB (WP_011408744.1),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,cold-shock protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30372574,PubMed,10.1111/mpp.12763,Mol Plant Pathol. 2018 Oct 29,gaoxw@njau.edu.cn,CspA was important for cellular growth at low temperature and for virulence against rice.,L Wu 2018,2018,4 genes,Wu-2018-Contribution of the cold shock protein,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12805,PHI:8638,UniProt,A0A0J9WX69,GenBank,ACD59248,,,PXO99A,CspC ( WP_011258799.1),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,integral membrane protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30372574,PubMed,10.1111/mpp.12763,Mol Plant Pathol. 2018 Oct 29,gaoxw@njau.edu.cn,CspA was important for cellular growth at low temperature and for virulence against rice.,L Wu 2018,2018,4 genes,Wu-2018-Contribution of the cold shock protein,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12806,PHI:8639,UniProt,A0A0K0GLJ4,GenBank,ACD59665,,,PXO99A,CspD ( WP_003488188.1),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30372574,PubMed,10.1111/mpp.12763,Mol Plant Pathol. 2018 Oct 29,gaoxw@njau.edu.cn,CspA was important for cellular growth at low temperature and for virulence against rice.,L Wu 2018,2018,4 genes,Wu-2018-Contribution of the cold shock protein,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12807,PHI:8640,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,transcriptional activator protein LasR,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30411474,PubMed,10.1111/1462-2920.14468,Environ Microbiol. 2018 Nov 8,haeussler@helmholtz-hzi.de,Flagellin appeared to be an important factor for survival of the ΔlasR mutant during chronic biofilm-associated infections. subcutaneous tumour tissue,A Lorenz 2018,2018,2 genes,Lorenz-2018-Importance of flagella in acute an,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12808,PHI:8640,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,PHI:8641,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,transcriptional activator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30411474,PubMed,10.1111/1462-2920.14468,Environ Microbiol. 2018 Nov 8,haeussler@helmholtz-hzi.de,Flagellin appeared to be an important factor for survival of the ΔlasR mutant during chronic biofilm-associated infections. subcutaneous tumour tissue,A Lorenz 2018,2018,2 genes,Lorenz-2018-Importance of flagella in acute an,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12809,PHI:8641,UniProt,P72151,,,,,PAO1,flic,,,,,,PHI:8640,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30411474,PubMed,10.1111/1462-2920.14468,Environ Microbiol. 2018 Nov 8,haeussler@helmholtz-hzi.de,Flagellin appeared to be an important factor for survival of the ΔlasR mutant during chronic biofilm-associated infections. subcutaneous tumour tissue,A Lorenz 2018,2018,2 genes,Lorenz-2018-Importance of flagella in acute an,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12810,PHI:8642,,no data found,GenBank,WP_013036113.1,,,,pdeA,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"The single-deletion mutants Ea1189 ΔpdeA, ΔpdeB and ΔpdeC exhibited similar levels of flagellar swimming motility as that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12811,PHI:8643,UniProt,D4I3P5,GenBank,WP_004160894.1,,,,pdeB,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"The single-deletion mutants Ea1189 ΔpdeA, ΔpdeB and ΔpdeC exhibited similar levels of flagellar swimming motility as that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12812,PHI:8644,UniProt,D4I4B4,GenBank,WP_004161053.1,,,,pdeC,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"The single-deletion mutants Ea1189 ΔpdeA, ΔpdeB and ΔpdeC exhibited similar levels of flagellar swimming motility as that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12813,PHI:8642,,no data found,GenBank,WP_013036113.1,,,,pdeA,,,,,,PHI:8643,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12814,PHI:8643,UniProt,D4I3P5,GenBank,WP_004160894.1,,,,pdeB,,,,,,PHI:8642,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12815,PHI:8642,,no data found,GenBank,WP_013036113.1,,,,pdeA,,,,,,PHI:8644,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12816,PHI:8644,UniProt,D4I4B4,GenBank,WP_004161053.1,,,,pdeC,,,,,,PHI:8642,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12817,PHI:8643,UniProt,D4I3P5,GenBank,WP_004160894.1,,,,pdeB,,,,,,PHI:8644,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12818,PHI:8644,UniProt,D4I4B4,GenBank,WP_004161053.1,,,,pdeC,,,,,,PHI:8643,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12819,PHI:8642,UniProt,D4I4B4,GenBank,WP_004161053.1,,,,pdeA,,,,,,PHI:8642; PHI:8643,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12820,PHI:8643,UniProt,D4I3P5,GenBank,WP_004160894.1,,,,pdeB,,,,,,PHI:8642; PHI:8644,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12821,PHI:8644,UniProt,D4I4B4,GenBank,WP_004161053.1,,,,pdeC,,,,,,PHI:8643; PHI:8644,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12822,PHI:8642,,no data found,GenBank,WP_013036113.1,,,,pdeA,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"The single-deletion mutants Ea1189 ΔpdeA, ΔpdeB and ΔpdeC exhibited similar levels of flagellar swimming motility as that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12823,PHI:8643,UniProt,D4I3P5,GenBank,WP_004160894.1,,,,pdeB,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"The single-deletion mutants Ea1189 ΔpdeA, ΔpdeB and ΔpdeC exhibited similar levels of flagellar swimming motility as that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12824,PHI:8644,UniProt,D4I4B4,GenBank,WP_004161053.1,,,,pdeC,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"The single-deletion mutants Ea1189 ΔpdeA, ΔpdeB and ΔpdeC exhibited similar levels of flagellar swimming motility as that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12825,PHI:8642,,no data found,GenBank,WP_013036113.1,,,,pdeA,,,,,,PHI:8643,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12826,PHI:8643,UniProt,D4I3P5,GenBank,WP_004160894.1,,,,pdeB,,,,,,PHI:8642,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12827,PHI:8642,,no data found,GenBank,WP_013036113.1,,,,pdeA,,,,,,PHI:8644,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12828,PHI:8644,UniProt,D4I4B4,GenBank,WP_004161053.1,,,,pdeC,,,,,,PHI:8642,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12829,PHI:8643,UniProt,D4I3P5,GenBank,WP_004160894.1,,,,pdeB,,,,,,PHI:8644,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12830,PHI:8644,UniProt,D4I4B4,GenBank,WP_004161053.1,,,,pdeC,,,,,,PHI:8643,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12831,PHI:8642,,no data found,GenBank,WP_013036113.1,,,,pdeA,,,,,,PHI:8642; PHI:8643,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12832,PHI:8643,UniProt,D4I3P5,GenBank,WP_004160894.1,,,,pdeB,,,,,,PHI:8642; PHI:8644,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12833,PHI:8644,UniProt,D4I4B4,GenBank,WP_004161053.1,,,,pdeC,,,,,,PHI:8643; PHI:8644,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,phosphodiesterase,,,amylovoran biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30366999,PubMed,10.1128/AEM.02233-18,Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e02233-18,sundin@msu.edu,"Double mutants Ea1189 ΔpdeAB, ΔpdeBC and ΔpdeAC, as well as triple mutant ΔpdeABC exhibited severely reduced motility compared to that of the WT.",R R Kharadi 2019,2019,3 genes,Kharadi-2019-Phosphodiesterase Genes Regulate,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12834,PHI:8645,UniProt,I1R9K2,GenBank,CEF71996,,,PH-1,FgLDHL1 (FGSG_00145),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhengmai,,,spikelet,lactate dehydrogenase,,,,reduced virulence,,,,,,increased,,reduced,reduced,no,H2O2; Congo red; SDS; NaCl; KCl; oxamic acid,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; oxamic acid: CHEBI:18058,,,,,gene deletion: full; gene complementation,,,YVS,30474697,PubMed,10.1007/s00294-018-0909-6,Curr Genet. 2018 Nov 24,GQL3333@163.com,"Both the single-gene deletion mutants of FgLDHL1 or FgLDHL2 exhibited phenotypic defects in vegetative growth, sporulation, spore germination, L-lactate biosynthesis and activity.",W Chen 2018,2018,2 genes,Chen-2018-Involvement of the two L-lactate deh,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12835,PHI:8646,UniProt,A0A0E0S4Y7,GenBank,CEF78562,,,PH-1,FgLDHL2 (FGSG_16220),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,stigma,lactate dehydrogenase,,,,reduced virulence,,,,,,wild type,,reduced,reduced,no,H2O2; Congo red; SDS; NaCl; KCl; oxamic acid,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; oxamic acid: CHEBI:18058,,,,,gene deletion: full; gene complementation,,,YVS,30474697,PubMed,10.1007/s00294-018-0909-6,Curr Genet. 2018 Nov 24,GQL3333@163.com,"Both the single-gene deletion mutants of FgLDHL1 or FgLDHL2 exhibited phenotypic defects in vegetative growth, sporulation, spore germination, L-lactate biosynthesis and activity.",W Chen 2018,2018,2 genes,Chen-2018-Involvement of the two L-lactate deh,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12836,PHI:8647,UniProt,Q8XE85,GenBank,BAB33895,,,Sakai,EspY3 (ECs0472),,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,extraintestinal infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,30373243,PubMed,10.3390/microorganisms6040112,Microorganisms. 2018 Oct 27;6(4). pii: E112,larzabal.mariano@inta.gob.ar,The EspY3 effector induced the elongation of polymerized actin pedestals in infected Caco-2 by EPEC.,M Larzábal 2018,2018,1 gene,Larzabal-2018-Novel Effector Protein EspY3 of,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12837,PHI:8647,UniProt,Q8XE85,GenBank,BAB33895,,,Sakai,EspY3 (ECs0472),,,,,,,562,Escherichia coli,574521,serotype O127:H6 strain E2348/69,extraintestinal infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,30373243,PubMed,10.3390/microorganisms6040112,Microorganisms. 2018 Oct 27;6(4). pii: E112,larzabal.mariano@inta.gob.ar,The EspY3 effector induced the elongation of polymerized actin pedestals in infected Caco-2 by EPEC.,M Larzábal 2018,2018,1 gene,Larzabal-2018-Novel Effector Protein EspY3 of,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12838,PHI:8648,UniProt,G4MSY9,GenBank,EHA54648,,,70-15,Poime4 (MGG_01492),chromosome 2,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,reduced virulence,,no,,,,wild type,wild type,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30535195,PubMed,10.1093/femsle/fny286,FEMS Microbiol Lett. 2018 Dec 11,jplu@zju.edu.cn,Disruption of N6-methyladenosine RNA methylation leads to reduced virulence or/and decreased conidiation in the rice blast fungus.,Y Shi 2018,2018,4 genes,Shi-2018-N6-methyladenosine RNA methylation is,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12839,PHI:8649,UniProt,G4MZ21,GenBank,EHA54488,,,70-15,Poalkb1 (MGG_01363),chromosome 2,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,putative oxidoreductase,,,,reduced virulence,,no,,,,wild type,wild type,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30535195,PubMed,10.1093/femsle/fny286,FEMS Microbiol Lett. 2018 Dec 11,jplu@zju.edu.cn,Disruption of N6-methyladenosine RNA methylation leads to reduced virulence or/and decreased conidiation in the rice blast fungus.,Y Shi 2018,2018,4 genes,Shi-2018-N6-methyladenosine RNA methylation is,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12840,PHI:8650,UniProt,G4MRQ6,GenBank,EHA58271,,,70-15,Poyth1 (MGG_04621),chromosome 1,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,reduced virulence,,no,,,,wild type,wild type,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30535195,PubMed,10.1093/femsle/fny286,FEMS Microbiol Lett. 2018 Dec 11,jplu@zju.edu.cn,Disruption of N6-methyladenosine RNA methylation leads to reduced virulence or/and decreased conidiation in the rice blast fungus.,Y Shi 2018,2018,4 genes,Shi-2018-N6-methyladenosine RNA methylation is,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12841,PHI:8651,UniProt,G4NB33,GenBank,EHA48795,,,70-15,Poyth2 (MGG_00637),chromosome 5,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,reduced virulence,,no,,,,reduced,wild type,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30535195,PubMed,10.1093/femsle/fny286,FEMS Microbiol Lett. 2018 Dec 11,jplu@zju.edu.cn,Disruption of N6-methyladenosine RNA methylation leads to reduced virulence or/and decreased conidiation in the rice blast fungus.,Y Shi 2018,2018,4 genes,Shi-2018-N6-methyladenosine RNA methylation is,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12842,PHI:8652,UniProt,P08179,GenBank,AAA83899,,,K-12,purN,,,,,,,562,Escherichia coli,364106,UTI89,infection,primates,9606,Homo sapiens (related: human),J82 cell line,,,J-82 cell,phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"Inactivation of purN and/or purT significantly affected UPEC invasion of human bladder cells, but not the intracellular survival, cytotoxicity levels to bladder cells were also diminished when both purN and purT were deleted, while single gene mutants did not differ from the wild type.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12843,PHI:8653,UniProt,P33221,GenBank,AAA23861,,,K-12,purT,,,,,,,562,Escherichia coli,364106,UTI89,infection,primates,9606,Homo sapiens (related: human),J82 cell line,,,J-82 cell,formate-dependent phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"Inactivation of purN and/or purT significantly affected UPEC invasion of human bladder cells, but not the intracellular survival, cytotoxicity levels to bladder cells were also diminished when both purN and purT were deleted, while single gene mutants did not differ from the wild type.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12844,PHI:8652,UniProt,P08179,GenBank,AAA83899,,,K-12,purN,,,,,,,562,Escherichia coli,364106,UTI89,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder,phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"Inactivation of purN and/or purT significantly affected UPEC invasion of human bladder cells, but not the intracellular survival, cytotoxicity levels to bladder cells were also diminished when both purN and purT were deleted, while single gene mutants did not differ from the wild type.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12845,PHI:8653,UniProt,P33221,GenBank,AAA23861,,,K-12,purT,,,,,,,562,Escherichia coli,364106,UTI89,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder,formate-dependent phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"Inactivation of purN and/or purT significantly affected UPEC invasion of human bladder cells, but not the intracellular survival, cytotoxicity levels to bladder cells were also diminished when both purN and purT were deleted, while single gene mutants did not differ from the wild type.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12846,PHI:8652,UniProt,P08179,GenBank,AAA83899,,,K-12,purN,,,,,,,562,Escherichia coli,364106,UTI89,infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"When infecting human macrophages, no differences were observed between UTI89 and mutants in uptake, survival or cytotoxicity.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12847,PHI:8653,UniProt,P33221,GenBank,AAA23861,,,K-12,purT,,,,,,,562,Escherichia coli,364106,UTI89,infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,formate-dependent phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"When infecting human macrophages, no differences were observed between UTI89 and mutants in uptake, survival or cytotoxicity.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12848,PHI:8652,UniProt,P08179,GenBank,AAA83899,,,K-12,purN,,,,,,PHI:8653,562,Escherichia coli,364106,UTI89,infection,primates,9606,Homo sapiens (related: human),J82 cell line,,,J-82 cell,phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"Inactivation of purN and/or purT significantly affected UPEC invasion of human bladder cells, but not the intracellular survival, cytotoxicity levels to bladder cells were also diminished when both purN and purT were deleted, while single gene mutants did not differ from the wild type.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12849,PHI:8653,UniProt,P33221,GenBank,AAA23861,,,K-12,purT,,,,,,PHI:8652,562,Escherichia coli,364106,UTI89,infection,primates,9606,Homo sapiens (related: human),J82 cell line,,,J-82 cell,formate-dependent phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"Inactivation of purN and/or purT significantly affected UPEC invasion of human bladder cells, but not the intracellular survival, cytotoxicity levels to bladder cells were also diminished when both purN and purT were deleted, while single gene mutants did not differ from the wild type.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12850,PHI:8652,UniProt,P08179,GenBank,AAA83899,,,K-12,purN,,,,,,PHI:8653,562,Escherichia coli,364106,UTI89,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder,phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"Inactivation of purN and/or purT significantly affected UPEC invasion of human bladder cells, but not the intracellular survival, cytotoxicity levels to bladder cells were also diminished when both purN and purT were deleted, while single gene mutants did not differ from the wild type.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12851,PHI:8653,UniProt,P33221,GenBank,AAA23861,,,K-12,purT,,,,,,PHI:8652,562,Escherichia coli,364106,UTI89,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder,formate-dependent phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"Inactivation of purN and/or purT significantly affected UPEC invasion of human bladder cells, but not the intracellular survival, cytotoxicity levels to bladder cells were also diminished when both purN and purT were deleted, while single gene mutants did not differ from the wild type.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12852,PHI:8652,UniProt,P08179,GenBank,AAA83899,,,K-12,purN,,,,,,PHI:8653,562,Escherichia coli,364106,UTI89,infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"When infecting human macrophages, no differences were observed between UTI89 and mutants in uptake, survival or cytotoxicity.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12853,PHI:8653,UniProt,P33221,GenBank,AAA23861,,,K-12,purT,,,,,,PHI:8652,562,Escherichia coli,364106,UTI89,infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,formate-dependent phosphoribosylglycinamide formyltransferase,,,purine biosynthesis,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30377949,PubMed,10.1007/s11033-018-4441-z,Mol Biol Rep. 2018 Oct 30,ahefr@sund.ku.dk,"When infecting human macrophages, no differences were observed between UTI89 and mutants in uptake, survival or cytotoxicity.",A I S Andersen-Civil 2018,2018,2 genes,Andersen-Civil-2018-The impact of inactivation,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12854,PHI:8654,UniProt,Q9F496,GenBank,CAC13110,,,3937,opgG,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Amandine,,,tuber,glucans biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12855,PHI:8655,UniProt,E0SJT2,GenBank,ADN00371,,,3937,envZ,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Amandine,,,tuber,sensory histidine kinase in two-component regulatory system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12856,PHI:8656,UniProt,E0SJT3,GenBank,ADN00372,,,3937,ompR,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Amandine,,,tuber,DNA-binding response regulator in two-component regulatory system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12857,PHI:8655,UniProt,E0SJT2,GenBank,ADN00371,,,3937,envZ,,,,,,PHI:8654,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Amandine,,,tuber,sensory histidine kinase in two-component regulatory system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12858,PHI:8654,UniProt,Q9F496,GenBank,CAC13110,,,3937,opgG,,,,,,PHI:8655,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Amandine,,,tuber,glucans biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12859,PHI:8656,UniProt,E0SJT3,GenBank,ADN00372,,,3937,ompR,,,,,,PHI:8654,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Amandine,,,tuber,DNA-binding response regulator in two-component regulatory system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12860,PHI:8654,UniProt,Q9F496,GenBank,CAC13110,,,3937,opgG,,,,,,PHI:8656,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Amandine,,,tuber,glucans biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12861,PHI:8654,UniProt,Q9F496,GenBank,CAC13110,,,3937,opgG,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,glucans biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12862,PHI:8655,UniProt,E0SJT2,GenBank,ADN00371,,,3937,envZ,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,sensory histidine kinase in two-component regulatory system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12863,PHI:8656,UniProt,E0SJT3,GenBank,ADN00372,,,3937,ompR,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,DNA-binding response regulator in two-component regulatory system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12864,PHI:8655,UniProt,E0SJT2,GenBank,ADN00371,,,3937,envZ,,,,,,PHI:8654,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,sensory histidine kinase in two-component regulatory system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12865,PHI:8654,UniProt,Q9F496,GenBank,CAC13110,,,3937,opgG,,,,,,PHI:8655,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,glucans biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12866,PHI:8656,UniProt,E0SJT3,GenBank,ADN00372,,,3937,ompR,,,,,,PHI:8654,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,DNA-binding response regulator in two-component regulatory system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12867,PHI:8654,UniProt,Q9F496,GenBank,CAC13110,,,3937,opgG,,,,,,PHI:8656,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,glucans biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30425688,PubMed,10.3389/fmicb.2018.02459,Front Microbiol. 2018 Oct 30;9:2459,jean-marie.lacroix@univ-lille.fr,Inactivation of the EnvZ/OmpR system in an OPG-defective mutant restoreed full synthesis of pectinase but only partial virulence.,M Caby 2018,2018,3 genes,Caby-2018-The EnvZ-OmpR Two-Component Signalin,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12868,PHI:8657,UniProt,B3GXA0,GenBank,ACE61252,,,AP76,flp1,,,,,,,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,type IVb pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30419341,PubMed,10.1016/j.micpath.2018.11.010,Microb Pathog. 2018 Nov 10;126:310-317,rzhou@mail.hzau.edu.cn,"The abilities of biofilm formation, cell adhesion, resistance to phagocytosis, survival in swine whole blood, and in vivo colonization of the two mutants were significantly reduced compared with those of the parental strain.",T Li 2018,2018,2 genes,Li-2018-The roles of flp1 and tadD in Actinoba,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12869,PHI:8657,UniProt,B3GXA0,GenBank,ACE61252,,,AP76,flp1,,,,,,,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),SJPL,,,lung epithelial cell,type IVb pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30419341,PubMed,10.1016/j.micpath.2018.11.010,Microb Pathog. 2018 Nov 10;126:310-317,rzhou@mail.hzau.edu.cn,"The abilities of biofilm formation, cell adhesion, resistance to phagocytosis, survival in swine whole blood, and in vivo colonization of the two mutants were significantly reduced compared with those of the parental strain.",T Li 2018,2018,2 genes,Li-2018-The roles of flp1 and tadD in Actinoba,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12870,PHI:8657,UniProt,B3GXA0,GenBank,ACE61252,,,AP76,flp1,,,,,,,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),PIEC,,,iliac artery endothelial cell line,type IVb pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30419341,PubMed,10.1016/j.micpath.2018.11.010,Microb Pathog. 2018 Nov 10;126:310-317,rzhou@mail.hzau.edu.cn,"The abilities of biofilm formation, cell adhesion, resistance to phagocytosis, survival in swine whole blood, and in vivo colonization of the two mutants were significantly reduced compared with those of the parental strain.",T Li 2018,2018,2 genes,Li-2018-The roles of flp1 and tadD in Actinoba,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12871,PHI:8657,UniProt,B3GXA0,GenBank,ACE61252,,,AP76,flp1,,,,,,,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood; lung; spleen,type IVb pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30419341,PubMed,10.1016/j.micpath.2018.11.010,Microb Pathog. 2018 Nov 10;126:310-317,rzhou@mail.hzau.edu.cn,"The abilities of biofilm formation, cell adhesion, resistance to phagocytosis, survival in swine whole blood, and in vivo colonization of the two mutants were significantly reduced compared with those of the parental strain.",T Li 2018,2018,2 genes,Li-2018-The roles of flp1 and tadD in Actinoba,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12872,PHI:8657,UniProt,B3GXA0,GenBank,ACE61252,,,AP76,flp1,,,,,,,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,type IVb pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30419341,PubMed,10.1016/j.micpath.2018.11.010,Microb Pathog. 2018 Nov 10;126:310-317,rzhou@mail.hzau.edu.cn,"The abilities of biofilm formation, cell adhesion, resistance to phagocytosis, survival in swine whole blood, and in vivo colonization of the two mutants were significantly reduced compared with those of the parental strain.",T Li 2018,2018,2 genes,Li-2018-The roles of flp1 and tadD in Actinoba,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12873,PHI:8658,UniProt,A3MZR5,GenBank,ABN73651,,,L20,tadD,,,,,,,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,tight adherence protein involved in assembly of Flp pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30419341,PubMed,10.1016/j.micpath.2018.11.010,Microb Pathog. 2018 Nov 10;126:310-317,rzhou@mail.hzau.edu.cn,"The abilities of biofilm formation, cell adhesion, resistance to phagocytosis, survival in swine whole blood, and in vivo colonization of the two mutants were significantly reduced compared with those of the parental strain.",T Li 2018,2018,2 genes,Li-2018-The roles of flp1 and tadD in Actinoba,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12874,PHI:8658,UniProt,A3MZR5,GenBank,ABN73651,,,L20,tadD,,,,,,,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),SJPL,,,lung epithelial cell,tight adherence protein involved in assembly of Flp pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30419341,PubMed,10.1016/j.micpath.2018.11.010,Microb Pathog. 2018 Nov 10;126:310-317,rzhou@mail.hzau.edu.cn,"The abilities of biofilm formation, cell adhesion, resistance to phagocytosis, survival in swine whole blood, and in vivo colonization of the two mutants were significantly reduced compared with those of the parental strain.",T Li 2018,2018,2 genes,Li-2018-The roles of flp1 and tadD in Actinoba,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12875,PHI:8658,UniProt,A3MZR5,GenBank,ABN73651,,,L20,tadD,,,,,,,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),PIEC,,,iliac artery endothelial cell line,tight adherence protein involved in assembly of Flp pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30419341,PubMed,10.1016/j.micpath.2018.11.010,Microb Pathog. 2018 Nov 10;126:310-317,rzhou@mail.hzau.edu.cn,"The abilities of biofilm formation, cell adhesion, resistance to phagocytosis, survival in swine whole blood, and in vivo colonization of the two mutants were significantly reduced compared with those of the parental strain.",T Li 2018,2018,2 genes,Li-2018-The roles of flp1 and tadD in Actinoba,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12876,PHI:8658,UniProt,A3MZR5,GenBank,ABN73651,,,L20,tadD,,,,,,,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood; lung; spleen,tight adherence protein involved in assembly of Flp pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30419341,PubMed,10.1016/j.micpath.2018.11.010,Microb Pathog. 2018 Nov 10;126:310-317,rzhou@mail.hzau.edu.cn,"The abilities of biofilm formation, cell adhesion, resistance to phagocytosis, survival in swine whole blood, and in vivo colonization of the two mutants were significantly reduced compared with those of the parental strain.",T Li 2018,2018,2 genes,Li-2018-The roles of flp1 and tadD in Actinoba,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12877,PHI:8658,UniProt,A3MZR5,GenBank,ABN73651,,,L20,tadD,,,,,,,715,Actinobacillus pleuropneumoniae,228399,4074,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,tight adherence protein involved in assembly of Flp pilus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30419341,PubMed,10.1016/j.micpath.2018.11.010,Microb Pathog. 2018 Nov 10;126:310-317,rzhou@mail.hzau.edu.cn,"The abilities of biofilm formation, cell adhesion, resistance to phagocytosis, survival in swine whole blood, and in vivo colonization of the two mutants were significantly reduced compared with those of the parental strain.",T Li 2018,2018,2 genes,Li-2018-The roles of flp1 and tadD in Actinoba,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12878,PHI:8659,,no data found,,,,,,fnrS,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; small intestine; large intestine,small regulatory RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30484918,PubMed,10.1111/mmi.14174,Mol Microbiol. 2018 Nov 28,slauch@illinois.edu,"Loss of FnrS and ArcZ confered a SPI1-independent competitive disadvantage, the increased expression of SPI1 in the sRNA double mutant led to an overall increase in invasion.",K Kim 2018,2018,3 genes,Kim-2018-Oxygen-dependent regulation of SPI1 t,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12879,PHI:8660,,no data found,,,,,,arcZ,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; small intestine; large intestine,small regulatory RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30484918,PubMed,10.1111/mmi.14174,Mol Microbiol. 2018 Nov 28,slauch@illinois.edu,"Loss of FnrS and ArcZ confered a SPI1-independent competitive disadvantage, the increased expression of SPI1 in the sRNA double mutant led to an overall increase in invasion.",K Kim 2018,2018,3 genes,Kim-2018-Oxygen-dependent regulation of SPI1 t,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12880,PHI:8659,,no data found,,,,,,fnrS,,,,,,PHI:8660,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; small intestine; large intestine,small regulatory RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30484918,PubMed,10.1111/mmi.14174,Mol Microbiol. 2018 Nov 28,slauch@illinois.edu,"Loss of FnrS and ArcZ confered a SPI1-independent competitive disadvantage, the increased expression of SPI1 in the sRNA double mutant led to an overall increase in invasion.",K Kim 2018,2018,3 genes,Kim-2018-Oxygen-dependent regulation of SPI1 t,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12881,PHI:8660,,no data found,,,,,,arcZ,,,,,,PHI:8659,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; small intestine; large intestine,small regulatory RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30484918,PubMed,10.1111/mmi.14174,Mol Microbiol. 2018 Nov 28,slauch@illinois.edu,"Loss of FnrS and ArcZ confered a SPI1-independent competitive disadvantage, the increased expression of SPI1 in the sRNA double mutant led to an overall increase in invasion.",K Kim 2018,2018,3 genes,Kim-2018-Oxygen-dependent regulation of SPI1 t,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12882,PHI:8659,,no data found,,,,,,fnrS,,,,,,PHI:8660; PHI:8661,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; small intestine; large intestine,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30484918,PubMed,10.1111/mmi.14174,Mol Microbiol. 2018 Nov 28,slauch@illinois.edu,"Loss of FnrS and ArcZ confered a SPI1-independent competitive disadvantage, the increased expression of SPI1 in the sRNA double mutant led to an overall increase in invasion.",K Kim 2018,2018,3 genes,Kim-2018-Oxygen-dependent regulation of SPI1 t,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12883,PHI:8660,,no data found,,,,,,arcZ,,,,,,PHI:8659; PHI:8661,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; small intestine; large intestine,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30484918,PubMed,10.1111/mmi.14174,Mol Microbiol. 2018 Nov 28,slauch@illinois.edu,"Loss of FnrS and ArcZ confered a SPI1-independent competitive disadvantage, the increased expression of SPI1 in the sRNA double mutant led to an overall increase in invasion.",K Kim 2018,2018,3 genes,Kim-2018-Oxygen-dependent regulation of SPI1 t,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12884,PHI:8661,,no data found,,,,,,spi1,,,,,,PHI:8659; PHI:8660,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; small intestine; large intestine,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30484918,PubMed,10.1111/mmi.14174,Mol Microbiol. 2018 Nov 28,slauch@illinois.edu,"Loss of FnrS and ArcZ confered a SPI1-independent competitive disadvantage, the increased expression of SPI1 in the sRNA double mutant led to an overall increase in invasion.",K Kim 2018,2018,3 genes,Kim-2018-Oxygen-dependent regulation of SPI1 t,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12885,PHI:8662,UniProt,A0A1I7RYM0,,,,,,BxSapB1 (BXY_0583800),,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,3350,Pinus thunbergii (related: Japanese black pine),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30358407,PubMed,10.1021/acs.jproteome.8b00579,J Proteome Res. 2018 Oct 25,xqwu@njfu.edu.cn,The relative expression levels of defense-related genes are significantly reduced in P. thunbergii infected with BxSapB1 silenced.,L Hu 2018,2018,1 gene,"Hu-2018-An effector, BxSapB1, induces cell dea",BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12886,PHI:8662,UniProt,A0A1I7RYM0,,,,,,BxSapB1 (BXY_0583800),,,,,,,6326,Bursaphelenchus xylophilus,,YW4,pine wilt,seed plants,3350,Pinus thunbergii (related: Japanese black pine),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30358407,PubMed,10.1021/acs.jproteome.8b00579,J Proteome Res. 2018 Oct 25,xqwu@njfu.edu.cn,The relative expression levels of defense-related genes are significantly reduced in P. thunbergii infected with BxSapB1 silenced.,L Hu 2018,2018,1 gene,"Hu-2018-An effector, BxSapB1, induces cell dea",BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12887,PHI:8662,UniProt,A0A1I7RYM0,,,,,,BxSapB1 (BXY_0583800),,,,,,,6326,Bursaphelenchus xylophilus,,YW4,pine wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30358407,PubMed,10.1021/acs.jproteome.8b00579,J Proteome Res. 2018 Oct 25,xqwu@njfu.edu.cn,Candidate effector BxSapB1 causes cell death when secreted to the apoplast in Nicotiana benthamiana.,L Hu 2018,2018,1 gene,"Hu-2018-An effector, BxSapB1, induces cell dea",BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12888,PHI:8663,UniProt,L7N681,GenBank,CCP44411,,,H37Rv,PE17 (Rv1646),,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; liver; spleen; kidney; peritoneal macrophage,PE family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,recombinant Mycobacterium smegmatis producing PE17 from M.tuberculosis was used,,YVS,30366126,PubMed,10.1016/j.micpath.2018.10.030,Microb Pathog. 2018 Oct 23;126:63-73,chenliping@caas.cn,"Mouse infection model confirmed that PE17 significantly prolonged the survival of M. smegmatis in vivo, aggravated lesions in organs of infected mice and promoted macrophage necrosis.",Z Li 2018,2018,1 gene,Li-2018-PE17 protein from Mycobacterium tuberc,BATCH_088A,2018-12-01,MC,,,,,,,,,,,,,
,,Record 12889,PHI:8664,UniProt,Q8Z3Y8,GenBank,AAO70495,,,Ty2,T2942/STIV,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colorectal adenocarcinoma cell,virulence-associated secretory protein,,,,reduced virulence,,,,,,,,,,no,SU11274,SU11274 CAS no.: CAS:658084-23-2,,,,,gene mutation,,,YVS,30426648,PubMed,10.1111/cmi.12982,Cell Microbiol. 2018 Nov 13:e12982,dasss.niced@gov.in,"Invasion of the WT, Ty2ΔSTIV and T3SS-1 mutant bacteria was progressively reduced with increasing doses of the Met inhibitor, indicating T3SS-1-independent invasion of S. Typhi by STIV–Met interaction.",R Chowdhury 2018,2018,2 genes,Chowdhury-2018-Epithelial invasion by Salmonel,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12890,PHI:8664,UniProt,Q8Z3Y8,GenBank,AAO70495,,,Ty2,T2942/STIV,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cecum; liver; spleen,virulence-associated secretory protein,,,,reduced virulence,,,,,,,,,,no,SU11274,SU11274 CAS no.: CAS:658084-23-2,,,,,gene mutation,,,YVS,30426648,PubMed,10.1111/cmi.12982,Cell Microbiol. 2018 Nov 13:e12982,dasss.niced@gov.in,"Invasion of the WT, Ty2ΔSTIV and T3SS-1 mutant bacteria was progressively reduced with increasing doses of the Met inhibitor, indicating T3SS-1-independent invasion of S. Typhi by STIV–Met interaction.",R Chowdhury 2018,2018,2 genes,Chowdhury-2018-Epithelial invasion by Salmonel,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12891,PHI:8665,UniProt,Q8Z489,GenBank,AAO70361,,,Ty2,invG,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colorectal adenocarcinoma cell,"invasin, outer membrane protein",,,,reduced virulence,,,,,,,,,,no,SU11274,SU11274 CAS no.: CAS:658084-23-2,,,,,gene mutation,,,YVS,30426648,PubMed,10.1111/cmi.12982,Cell Microbiol. 2018 Nov 13:e12982,dasss.niced@gov.in,"Invasion of the WT, Ty2ΔSTIV and T3SS-1 mutant bacteria was progressively reduced with increasing doses of the Met inhibitor, indicating T3SS-1-independent invasion of S. Typhi by STIV–Met interaction.",R Chowdhury 2018,2018,2 genes,Chowdhury-2018-Epithelial invasion by Salmonel,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12892,PHI:8666,UniProt,I1R9C6,GenBank,CEF71898,,,PH-1,FgKP4L-1 (FGSG_00060),chromosome 1,,,,,PHI:8667; PHI:8668; PHI:8669,5518,Fusarium graminearum,229533,PH-1,seedling rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Ning 7840,,,seedling,uncharacterized protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,gene deletion: cluster; gene complementation,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,Elimination of the FgKP4L-1/-2/-3 gene cluster from the fungal genome results in reduced virulence in seedling rot but not in Fusarium head blight (FHB).,S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12893,PHI:8667,UniProt,I1R9C7,GenBank,CEF71899,,,PH-1,FgKP4L-2 (FGSG_00061),chromosome 1,,,,,PHI:8666; PHI:8668; PHI:8669,5518,Fusarium graminearum,229533,PH-1,seedling rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Ning 7840,,,seedling,uncharacterized protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,gene deletion: cluster; gene complementation,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,Elimination of the FgKP4L-1/-2/-3 gene cluster from the fungal genome results in reduced virulence in seedling rot but not in Fusarium head blight (FHB).,S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12894,PHI:8668,UniProt,I1R9C8,GenBank,CEF71900,,,PH-1,FgKP4L-3 (FGSG_00062),chromosome 1,,,,,PHI:8666; PHI:8667; PHI:8669,5518,Fusarium graminearum,229533,PH-1,seedling rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Ning 7840,,,seedling,uncharacterized protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,gene deletion: cluster; gene complementation,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,Elimination of the FgKP4L-1/-2/-3 gene cluster from the fungal genome results in reduced virulence in seedling rot but not in Fusarium head blight (FHB).,S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12895,PHI:8669,UniProt,I1S1F0,GenBank,CEF75998,,,PH-1,FgKP4L-4 (FGSG_10551),chromosome 1,,,,,PHI:8666; PHI:8667; PHI:8668,5518,Fusarium graminearum,229533,PH-1,seedling rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Ning 7840,,,seedling,uncharacterized protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,gene deletion: cluster; gene complementation,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,Elimination of the FgKP4L-1/-2/-3 gene cluster from the fungal genome results in reduced virulence in seedling rot but not in Fusarium head blight (FHB).,S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12896,PHI:8667,UniProt,I1R9C7,GenBank,CEF71899,,,PH-1,FgKP4L-2 (FGSG_00061),chromosome 1,,,,,,5518,Fusarium graminearum,,,non-pathogenic,monocots,4565,Triticum aestivum (related: bread wheat),cv. Ning 7840,,,seedling,uncharacterized protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,gene deletion: cluster; gene complementation,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,"Recombinant FgKP4L-2 protein did not induce cell death in wheat leaves or spikelets, but inhibited root growth of young seedlings.",S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12897,PHI:8667,UniProt,I1R9C7,GenBank,CEF71899,,,PH-1,FgKP4L-2 (FGSG_00061),chromosome 1,,,,,,5518,Fusarium graminearum,,,non-pathogenic,monocots,4565,Triticum aestivum (related: bread wheat),cv. Auburn,,,seedling,uncharacterized protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,other evidence: heterologous expression of recombinant protein,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,"Recombinant FgKP4L-2 protein did not induce cell death in wheat leaves or spikelets, but inhibited root growth of young seedlings.",S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12898,PHI:8667,UniProt,I1R9C7,GenBank,CEF71899,,,PH-1,FgKP4L-2 (FGSG_00061),chromosome 1,,,,,,5518,Fusarium graminearum,,,non-pathogenic,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bess,,,seedling,uncharacterized protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,other evidence: heterologous expression of recombinant protein,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,"Recombinant FgKP4L-2 protein did not induce cell death in wheat leaves or spikelets, but inhibited root growth of young seedlings.",S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12899,PHI:8667,UniProt,I1R9C7,GenBank,CEF71899,,,PH-1,FgKP4L-2 (FGSG_00061),chromosome 1,,,,,,5518,Fusarium graminearum,,,non-pathogenic,monocots,4565,Triticum aestivum (related: bread wheat),cv. BR34,,,seedling,uncharacterized protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,other evidence: heterologous expression of recombinant protein,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,"Recombinant FgKP4L-2 protein did not induce cell death in wheat leaves or spikelets, but inhibited root growth of young seedlings.",S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12900,PHI:8667,UniProt,I1R9C7,GenBank,CEF71899,,,PH-1,FgKP4L-2 (FGSG_00061),chromosome 1,,,,,,5518,Fusarium graminearum,,,non-pathogenic,monocots,4565,Triticum aestivum (related: bread wheat),cv. Sumai 3,,,seedling,uncharacterized protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,other evidence: heterologous expression of recombinant protein,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,"Recombinant FgKP4L-2 protein did not induce cell death in wheat leaves or spikelets, but inhibited root growth of young seedlings.",S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12901,PHI:8667,UniProt,I1R9C7,GenBank,CEF71899,,,PH-1,FgKP4L-2 (FGSG_00061),chromosome 1,,,,,,5518,Fusarium graminearum,,,non-pathogenic,monocots,4565,Triticum aestivum (related: bread wheat),cv. Grandin,,,seedling,uncharacterized protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,other evidence: heterologous expression of recombinant protein,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,"Recombinant FgKP4L-2 protein did not induce cell death in wheat leaves or spikelets, but inhibited root growth of young seedlings.",S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12902,PHI:8667,UniProt,I1R9C7,GenBank,CEF71899,,,PH-1,FgKP4L-2 (FGSG_00061),chromosome 1,,,,,,5518,Fusarium graminearum,,,non-pathogenic,monocots,4565,Triticum aestivum (related: bread wheat),cv. ND495,,,seedling,uncharacterized protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,other evidence: heterologous expression of recombinant protein,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,"Recombinant FgKP4L-2 protein did not induce cell death in wheat leaves or spikelets, but inhibited root growth of young seedlings.",S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12903,PHI:8667,UniProt,I1R9C7,GenBank,CEF71899,,,PH-1,FgKP4L-2 (FGSG_00061),chromosome 1,,,,,,5518,Fusarium graminearum,,,non-pathogenic,monocots,4565,Triticum aestivum (related: bread wheat),cv. Russ,,,seedling,uncharacterized protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; sorbitol; CaCl2; ZnSO4,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; CaCl2: CHEBI:3312; ZnSO4: CHEBI:35176,,,,,other evidence: heterologous expression of recombinant protein,,,YVS,30465882,PubMed,10.1016/j.fgb.2018.11.002,Fungal Genet Biol. 2018 Nov 19;123:1-13,Shunwen.Lu@ars.usda.gov,"Recombinant FgKP4L-2 protein did not induce cell death in wheat leaves or spikelets, but inhibited root growth of young seedlings.",S Lu 2018,2018,4 genes,Lu-2018-Fusarium graminearum KP4-like proteins,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12904,PHI:8670,UniProt,G2XJR0,GenBank,EGY20763,,,VdLs.17,ACC deaminase (VDAG_10392),,,,,,,27337,Verticillium dahliae,,70V,Verticillium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),Never-ripe mutant,,,leaf,1-aminocyclopropane-1-carboxylate deaminase,,,,reduced virulence,,,,,,increased,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30520678,PubMed,10.1094/MPMI-07-18-0203-R,Mol Plant Microbe Interact. 2018 Dec 6,maria.tsolakidou@cut.ac.cy,Overexpression strains lowered ACC levels in the roots of infected plants while the amount of ACC in the roots of plants infected with deletion mutants increased and both types of mutant produced more ethylene than wild type (70V-WT) strain.,M D Tsolakidou 2018,2018,1 gene,Tsolakidou-2018-Disruption and overexpression,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12905,PHI:8670,UniProt,G2XJR0,GenBank,EGY20763,,,VdLs.17,ACC deaminase (VDAG_10392),,,,,,,27337,Verticillium dahliae,,70V,Verticillium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),Never-ripe mutant,,,leaf,1-aminocyclopropane-1-carboxylate deaminase,,,,increased virulence (hypervirulence),,,,,,increased,,,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30520678,PubMed,10.1094/MPMI-07-18-0203-R,Mol Plant Microbe Interact. 2018 Dec 6,maria.tsolakidou@cut.ac.cy,Overexpression strains lowered ACC levels in the roots of infected plants while the amount of ACC in the roots of plants infected with deletion mutants increased and both types of mutant produced more ethylene than wild type (70V-WT) strain.,M D Tsolakidou 2018,2018,1 gene,Tsolakidou-2018-Disruption and overexpression,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12906,PHI:8670,UniProt,G2XJR0,GenBank,EGY20763,,,VdLs.17,ACC deaminase (VDAG_10392),,,,,,,27337,Verticillium dahliae,,70V,Verticillium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,leaf,1-aminocyclopropane-1-carboxylate deaminase,,,,reduced virulence,,,,,,increased,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30520678,PubMed,10.1094/MPMI-07-18-0203-R,Mol Plant Microbe Interact. 2018 Dec 6,maria.tsolakidou@cut.ac.cy,Overexpression strains lowered ACC levels in the roots of infected plants while the amount of ACC in the roots of plants infected with deletion mutants increased and both types of mutant produced more ethylene than wild type (70V-WT) strain.,M D Tsolakidou 2018,2018,1 gene,Tsolakidou-2018-Disruption and overexpression,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12907,PHI:8670,UniProt,G2XJR0,GenBank,EGY20763,,,VdLs.17,ACC deaminase (VDAG_10392),,,,,,,27337,Verticillium dahliae,,70V,Verticillium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,leaf,1-aminocyclopropane-1-carboxylate deaminase,,,,increased virulence (hypervirulence),,,,,,increased,,,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30520678,PubMed,10.1094/MPMI-07-18-0203-R,Mol Plant Microbe Interact. 2018 Dec 6,maria.tsolakidou@cut.ac.cy,Overexpression strains lowered ACC levels in the roots of infected plants while the amount of ACC in the roots of plants infected with deletion mutants increased and both types of mutant produced more ethylene than wild type (70V-WT) strain.,M D Tsolakidou 2018,2018,1 gene,Tsolakidou-2018-Disruption and overexpression,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12908,PHI:8670,UniProt,G2XJR0,GenBank,EGY20763,,,VdLs.17,ACC deaminase (VDAG_10392),,,,,,,27337,Verticillium dahliae,,70V,Verticillium wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Black Beauty,,,leaf,1-aminocyclopropane-1-carboxylate deaminase,,,,reduced virulence,,,,,,increased,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30520678,PubMed,10.1094/MPMI-07-18-0203-R,Mol Plant Microbe Interact. 2018 Dec 6,maria.tsolakidou@cut.ac.cy,Overexpression strains lowered ACC levels in the roots of infected plants while the amount of ACC in the roots of plants infected with deletion mutants increased and both types of mutant produced more ethylene than wild type (70V-WT) strain.,M D Tsolakidou 2018,2018,1 gene,Tsolakidou-2018-Disruption and overexpression,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12909,PHI:8670,UniProt,G2XJR0,GenBank,EGY20763,,,VdLs.17,ACC deaminase (VDAG_10392),,,,,,,27337,Verticillium dahliae,,70V,Verticillium wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Black Beauty,,,leaf,1-aminocyclopropane-1-carboxylate deaminase,,,,increased virulence (hypervirulence),,,,,,increased,,,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30520678,PubMed,10.1094/MPMI-07-18-0203-R,Mol Plant Microbe Interact. 2018 Dec 6,maria.tsolakidou@cut.ac.cy,Overexpression strains lowered ACC levels in the roots of infected plants while the amount of ACC in the roots of plants infected with deletion mutants increased and both types of mutant produced more ethylene than wild type (70V-WT) strain.,M D Tsolakidou 2018,2018,1 gene,Tsolakidou-2018-Disruption and overexpression,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12910,PHI:8671,UniProt,J4KQS2,GenBank,EJP69699,,,ARSEF 2860,phr1 (EJP69699),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DNA photolyase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30552186,PubMed,10.1128/AEM.02459-18,Appl Environ Microbiol. 2018 Dec 14. pii: AEM.02459-18,mgfeng@zju.edu.cn,"The results indicated no substantial role of each CPF gene in the fungal growth, conidiation and virulence, and overexpression of phr1 or phr2 enhanced conidial UVB resistance and photoreactivation efficiency.",D Y Wang 2018,2018,3 genes,Wang-2018-Two photolyases repair distinct DNA,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12911,PHI:8672,UniProt,J4WK53,GenBank,EJP70165,,,ARSEF 2860,phr2 (EJP70165),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DNA photolyase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30552186,PubMed,10.1128/AEM.02459-18,Appl Environ Microbiol. 2018 Dec 14. pii: AEM.02459-18,mgfeng@zju.edu.cn,"The results indicated no substantial role of each CPF gene in the fungal growth, conidiation and virulence, and overexpression of phr1 or phr2 enhanced conidial UVB resistance and photoreactivation efficiency.",D Y Wang 2018,2018,3 genes,Wang-2018-Two photolyases repair distinct DNA,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12912,PHI:8673,UniProt,J4US35,GenBank,EJP68422,,,ARSEF 2860,cryD (EJP68422),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DASH family cryptochrome,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30552186,PubMed,10.1128/AEM.02459-18,Appl Environ Microbiol. 2018 Dec 14. pii: AEM.02459-18,mgfeng@zju.edu.cn,"The results indicated no substantial role of each CPF gene in the fungal growth, conidiation and virulence.",D Y Wang 2018,2018,3 genes,Wang-2018-Two photolyases repair distinct DNA,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12913,PHI:8674,UniProt,C5AFJ6,GenBank,ACR28603,,,BGR1,hfq1 (bglu_1g14550),chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),var. glutinosa cv. Blanco,,,inflorescence,RNA-binding protein Hfq,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30369851,PubMed,10.5423/PPJ.OA.06.2018.0097,Plant Pathol J. 2018 Oct;34(5):412-425,yseo2011@pusan.ac.kr,The hfq1 gene showed more influence on bacterial motility and toxoflavin production than the hfq2 gene.,J Kim 2018,2018,2 genes,Kim-2018-The Roles of Two hfq Genes in the Vir,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12914,PHI:8675,UniProt,C5AGX2,GenBank,ACR29079,,,BGR1,hfq2 (bglu_1g19700),chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),var. glutinosa cv. Blanco,,,inflorescence,RNA-binding protein Hfq,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30369851,PubMed,10.5423/PPJ.OA.06.2018.0097,Plant Pathol J. 2018 Oct;34(5):412-425,yseo2011@pusan.ac.kr,The hfq1 gene showed more influence on bacterial motility and toxoflavin production than the hfq2 gene.,J Kim 2018,2018,2 genes,Kim-2018-The Roles of Two hfq Genes in the Vir,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12915,PHI:8674,UniProt,C5AFJ6,GenBank,ACR28603,,,BGR1,hfq1 (bglu_1g14550),chromosome 1,,,,,PHI:8675,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),var. glutinosa cv. Blanco,,,inflorescence,RNA-binding protein Hfq,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30369851,PubMed,10.5423/PPJ.OA.06.2018.0097,Plant Pathol J. 2018 Oct;34(5):412-425,yseo2011@pusan.ac.kr,The hfq1 gene showed more influence on bacterial motility and toxoflavin production than the hfq2 gene.,J Kim 2018,2018,2 genes,Kim-2018-The Roles of Two hfq Genes in the Vir,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12916,PHI:8675,UniProt,C5AGX2,GenBank,ACR29079,,,BGR1,hfq2 (bglu_1g19700),chromosome 1,,,,,PHI:8674,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),var. glutinosa cv. Blanco,,,inflorescence,RNA-binding protein Hfq,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30369851,PubMed,10.5423/PPJ.OA.06.2018.0097,Plant Pathol J. 2018 Oct;34(5):412-425,yseo2011@pusan.ac.kr,The hfq1 gene showed more influence on bacterial motility and toxoflavin production than the hfq2 gene.,J Kim 2018,2018,2 genes,Kim-2018-The Roles of Two hfq Genes in the Vir,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12917,PHI:8676,UniProt,Q8NL12,GenBank,AAM35959,,,306,hupB (XAC1081),,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2708,Citrus x limon (related: lemon),cv. Genova,,,leaf,histone-like protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,30537413,PubMed,10.1111/mpp.12777,Mol Plant Pathol. 2018 Dec 8,avojnov@centromilstein.org.ar,The hupB mutant was essentially non-motile as absecne of HupB led to the loss of flagellum.,V P Conforte 2018,2018,1 gene,Conforte-2018-The histone-like protein HupB in,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12918,PHI:8677,UniProt,Q8Y282,GenBank,CAD13982,,,GMI1000,RSc0454,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Hongyangli,,,leaf; petiole,FAD-linked oxidase,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30540527,PubMed,10.1094/MPMI-08-18-0224-R,Mol Plant Microbe Interact. 2018 Dec 12,hszou@fafu.edu.cn,"A single DUF3683, LDH, or SDH domain was insufficient to restore bacterial pathogenicity.",X Hu 2018,2018,1 gene,Hu-2018-The RSc0454 encoded FAD-linked oxidase,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12919,PHI:8677,UniProt,Q8Y282,GenBank,CAD13982,,,GMI1000,RSc0454,,mutant expressing DUF3683 domain,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Hongyangli,,,leaf; petiole,FAD-linked oxidase,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30540527,PubMed,10.1094/MPMI-08-18-0224-R,Mol Plant Microbe Interact. 2018 Dec 12,hszou@fafu.edu.cn,"A single DUF3683, LDH, or SDH domain was insufficient to restore bacterial pathogenicity.",X Hu 2018,2018,1 gene,Hu-2018-The RSc0454 encoded FAD-linked oxidase,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12920,PHI:8677,UniProt,Q8Y282,GenBank,CAD13982,,,GMI1000,RSc0454,,mutant expressing LDH domain,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Hongyangli,,,leaf; petiole,FAD-linked oxidase,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30540527,PubMed,10.1094/MPMI-08-18-0224-R,Mol Plant Microbe Interact. 2018 Dec 12,hszou@fafu.edu.cn,"A single DUF3683, LDH, or SDH domain was insufficient to restore bacterial pathogenicity.",X Hu 2018,2018,1 gene,Hu-2018-The RSc0454 encoded FAD-linked oxidase,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12921,PHI:8677,UniProt,Q8Y282,GenBank,CAD13982,,,GMI1000,RSc0454,,mutant expressing SDH domain,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Hongyangli,,,leaf; petiole,FAD-linked oxidase,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30540527,PubMed,10.1094/MPMI-08-18-0224-R,Mol Plant Microbe Interact. 2018 Dec 12,hszou@fafu.edu.cn,"A single DUF3683, LDH, or SDH domain was insufficient to restore bacterial pathogenicity.",X Hu 2018,2018,1 gene,Hu-2018-The RSc0454 encoded FAD-linked oxidase,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12922,PHI:8678,UniProt,A0A0T9VTM6,GenBank,CNR38834,,,CH43,SopE2,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,typhoid,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30532744,PubMed,10.3389/fmicb.2018.02810,Front Microbiol. 2018 Nov 23;9:2810.,yoonh@ajou.ac.kr,Outer membrane vesicles (OMVs) harboring active T3SS1 effectors during Salmonella infection complemented the attenuated invasion of ΔsopE2 strain into host cell.,S I Kim 2018,2018,1 gene,Kim-2018-Secretion of Salmonella Pathogenicity,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12923,PHI:8679,UniProt,Q8XQT8,GenBank,CAD18281,,,GMI1000,RipN (CAD18281.1),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,type III effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: overexpressing transgenic plants,,,YVS,30499216,PubMed,10.1111/mpp.12773,Mol Plant Pathol. 2018 Nov 30,luyj@mail.sysu.edu.cn,"RipN, a Nudix hydrolase, altered the NADH/NAD+ ratio of plant and contributed to R. solanacearum virulence by suppressing the PTI of host.",Y Sun 2018,2018,1 gene,Sun-2018-The Ralstonia solanacearum effector R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12924,PHI:8679,UniProt,Q8XQT8,GenBank,CAD18281,,,GMI1000,RipN (CAD18281.1),,"essential amino acids at position 219, 220, 223 and 224 changed into Glutamine to get catalytically inactive mutant",,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,type III effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: overexpressing transgenic plants,,,YVS,30499216,PubMed,10.1111/mpp.12773,Mol Plant Pathol. 2018 Nov 30,luyj@mail.sysu.edu.cn,"RipN, a Nudix hydrolase, altered the NADH/NAD+ ratio of plant and contributed to R. solanacearum virulence by suppressing the PTI of host.",Y Sun 2018,2018,1 gene,Sun-2018-The Ralstonia solanacearum effector R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12925,PHI:8680,,no data found,GenBank,CEJ17230,,,IPO1609,RipAB,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. E-Potato 3,,,leaf,effector protein,,,ca2+ pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30499228,PubMed,10.1111/mpp.12774,Mol Plant Pathol. 2018 Nov 30,Chenhuilan@mail.hzau.edu.cn,RipAB interfered with Ca2+ dependent gene expression to promote disease development in potato.,X Zheng 2018,2018,6 genes,Zheng-2018-A systematic screen of conserved R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12926,PHI:8680,,no data found,GenBank,CEJ17230,,,IPO1609,RipAB,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. E-Potato 3,,,leaf,effector protein,,,ca2+ pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30499228,PubMed,10.1111/mpp.12774,Mol Plant Pathol. 2018 Nov 30,Chenhuilan@mail.hzau.edu.cn,RipAB interfered with Ca2+ dependent gene expression to promote disease development in potato.,X Zheng 2018,2018,6 genes,Zheng-2018-A systematic screen of conserved R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12927,PHI:8680,,no data found,GenBank,CEJ17230,,,IPO1609,RipAB,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4108,Solanum chacoense (related: chaco potato),cv. C9701,,,leaf,effector protein,,,ca2+ pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30499228,PubMed,10.1111/mpp.12774,Mol Plant Pathol. 2018 Nov 30,Chenhuilan@mail.hzau.edu.cn,RipAB interfered with Ca2+ dependent gene expression to promote disease development in potato.,X Zheng 2018,2018,6 genes,Zheng-2018-A systematic screen of conserved R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12928,PHI:8681,,no data found,GenBank,CEJ20776,,,IPO1609,RipAM,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4108,Solanum chacoense (related: chaco potato),cv. C9701,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30499228,PubMed,10.1111/mpp.12774,Mol Plant Pathol. 2018 Nov 30,Chenhuilan@mail.hzau.edu.cn,RipAB interfered with Ca2+ dependent gene expression to promote disease development in potato.,X Zheng 2018,2018,6 genes,Zheng-2018-A systematic screen of conserved R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12929,PHI:8682,,no data found,GenBank,CEJ17197,,,IPO1609,RipAN,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4108,Solanum chacoense (related: chaco potato),cv. C9701,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30499228,PubMed,10.1111/mpp.12774,Mol Plant Pathol. 2018 Nov 30,Chenhuilan@mail.hzau.edu.cn,RipAB interfered with Ca2+ dependent gene expression to promote disease development in potato.,X Zheng 2018,2018,6 genes,Zheng-2018-A systematic screen of conserved R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12930,PHI:8683,,no data found,GenBank,CEJ16658,,,IPO1609,RipBH,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4108,Solanum chacoense (related: chaco potato),cv. C9701,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30499228,PubMed,10.1111/mpp.12774,Mol Plant Pathol. 2018 Nov 30,Chenhuilan@mail.hzau.edu.cn,RipAB interfered with Ca2+ dependent gene expression to promote disease development in potato.,X Zheng 2018,2018,6 genes,Zheng-2018-A systematic screen of conserved R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12931,PHI:8680,,no data found,GenBank,CEJ17230,,,IPO1609,RipAB,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,ca2+ pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30499228,PubMed,10.1111/mpp.12774,Mol Plant Pathol. 2018 Nov 30,Chenhuilan@mail.hzau.edu.cn,RipAB interfered with Ca2+ dependent gene expression to promote disease development in potato.,X Zheng 2018,2018,6 genes,Zheng-2018-A systematic screen of conserved R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12932,PHI:8684,,no data found,GenBank,CEJ19312,,,IPO1609,RipV1,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30499228,PubMed,10.1111/mpp.12774,Mol Plant Pathol. 2018 Nov 30,Chenhuilan@mail.hzau.edu.cn,RipAB interfered with Ca2+ dependent gene expression to promote disease development in potato.,X Zheng 2018,2018,6 genes,Zheng-2018-A systematic screen of conserved R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12933,PHI:8683,,no data found,GenBank,CEJ16658,,,IPO1609,RipBH,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30499228,PubMed,10.1111/mpp.12774,Mol Plant Pathol. 2018 Nov 30,Chenhuilan@mail.hzau.edu.cn,RipAB interfered with Ca2+ dependent gene expression to promote disease development in potato.,X Zheng 2018,2018,6 genes,Zheng-2018-A systematic screen of conserved R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12934,PHI:8685,,no data found,GenBank,ALF90854,,,UY031,RipF2,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30499228,PubMed,10.1111/mpp.12774,Mol Plant Pathol. 2018 Nov 30,Chenhuilan@mail.hzau.edu.cn,RipAB interfered with Ca2+ dependent gene expression to promote disease development in potato.,X Zheng 2018,2018,6 genes,Zheng-2018-A systematic screen of conserved R,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12935,PHI:8686,UniProt,B2SU53,GenBank,ACD58243,,,PXO99A,PthXo1,,pthXo1 derivatives with the conserved five amino acid residues of NLS2 substituted by alanine individually,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. Xian cv. IR24,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30499169,PubMed,10.1111/mpp.12772,Mol Plant Pathol. 2018 Nov 30,myuan@mail.hzau.edu.cn,Direct interaction between the second nuclear localization signal of TALEs of Xoo or Xoc and OsImpa1a or OsImpa1b was required for the transportation of TALEs into the nucleus. Host gene alteration data available for OsImpa1a/1b.,S Hui 2018,2018,1 gene,Hui-2018-TALE-carrying bacterial pathogens tra,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12936,PHI:8686,UniProt,B2SU53,GenBank,ACD58243,,,PXO99A,PthXo1,,pthXo1 derivatives with the conserved five amino acid residues of NLS2 substituted by alanine individually,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),subsp. Xian cv. IR24,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30499169,PubMed,10.1111/mpp.12772,Mol Plant Pathol. 2018 Nov 30,myuan@mail.hzau.edu.cn,Direct interaction between the second nuclear localization signal of TALEs of Xoo or Xoc and OsImpa1a or OsImpa1b was required for the transportation of TALEs into the nucleus. Host gene alteration data available for OsImpa1a/1b.,S Hui 2018,2018,1 gene,Hui-2018-TALE-carrying bacterial pathogens tra,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12937,PHI:8687,UniProt,J9VVF7,GenBank,AFR98427,,,H99,Pas3 (CNAG_06200),chromosome 12,,,Bre1,UniProt: P0CQ62; GenBank: AAW45565,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,NaCl; Congo red; fludioxonil,NaCl: CHEBI:26710; Congo red (CR): CHEBI:34653; fludioxonil: CHEBI:81763,,,,,gene deletion: full; gene complementation,,,YVS,30425151,PubMed,10.1128/mBio.02135-18,MBio. 2018 Nov 13;9(6). pii: e02135-18,xiaorong.lin@uga.edu,"PAS domain signaling regulator, Pas3 interacted with a chromatin modifier to control filamentation through their impact on cryptococcal transcriptome.",Y Zhao 2018,2018,1 gene,Zhao-2018-PAS Domain Protein Pas3 Interacts wi,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12938,PHI:8687,UniProt,J9VVF7,GenBank,AFR98427,,,H99,Pas3 (CNAG_06200),chromosome 12,,,Bre1,UniProt: P0CQ62; GenBank: AAW45565,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,NaCl; Congo red; fludioxonil,NaCl: CHEBI:26710; Congo red (CR): CHEBI:34653; fludioxonil: CHEBI:81763,,,,,gene deletion: full; gene complementation,,,YVS,30425151,PubMed,10.1128/mBio.02135-18,MBio. 2018 Nov 13;9(6). pii: e02135-18,xiaorong.lin@uga.edu,"PAS domain signaling regulator, Pas3 interacted with a chromatin modifier to control filamentation through their impact on cryptococcal transcriptome.",Y Zhao 2018,2018,1 gene,Zhao-2018-PAS Domain Protein Pas3 Interacts wi,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12939,PHI:8687,UniProt,J9VVF7,GenBank,AFR98427,,,H99,Pas3 (CNAG_06200),chromosome 12,,,Bre1,UniProt: P0CQ62; GenBank: AAW45565,,5207,Cryptococcus neoformans,1396488,XL280,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,NaCl; Congo red; fludioxonil,NaCl: CHEBI:26710; Congo red (CR): CHEBI:34653; fludioxonil: CHEBI:81763,,,,,gene deletion: full; gene complementation,,,YVS,30425151,PubMed,10.1128/mBio.02135-18,MBio. 2018 Nov 13;9(6). pii: e02135-18,xiaorong.lin@uga.edu,"PAS domain signaling regulator, Pas3 interacted with a chromatin modifier to control filamentation through their impact on cryptococcal transcriptome.",Y Zhao 2018,2018,1 gene,Zhao-2018-PAS Domain Protein Pas3 Interacts wi,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12940,PHI:8688,UniProt,D2TU76,GenBank,CBG90542,,,ICC168,cpxR,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,gut,two-component response regulator,,,,reduced virulence,,,,,,,,,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,30536519,PubMed,10.1111/mmi.14182,Mol Microbiol. 2018 Dec 9,bfinlay@interchange.ubc.ca,"Mouse infections with C. rodentium strains lacking individual Cpx-regulated genes showed that the chaperone/protease DegP and the disulfide bond oxidoreductase DsbA were essential for infection, but Cpx regulation of these genes did not fully account for attenuation of C. rodentium.",S L Vogt 2018,2018,5 genes,Vogt-2018-Characterization of the Citrobacter,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12941,PHI:8689,UniProt,D2TU77,GenBank,CBG90543,,,ICC168,cpxA,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,gut,two-component sensor kinase,,,,reduced virulence,,,,,,,,,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,30536519,PubMed,10.1111/mmi.14182,Mol Microbiol. 2018 Dec 9,bfinlay@interchange.ubc.ca,"Mouse infections with C. rodentium strains lacking individual Cpx-regulated genes showed that the chaperone/protease DegP and the disulfide bond oxidoreductase DsbA were essential for infection, but Cpx regulation of these genes did not fully account for attenuation of C. rodentium.",S L Vogt 2018,2018,5 genes,Vogt-2018-Characterization of the Citrobacter,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12942,PHI:8688,UniProt,D2TU76,GenBank,CBG90542,,,ICC168,cpxR,,,,,,PHI:8689,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,gut,two-component response regulator,,,,reduced virulence,,,,,,,,,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,30536519,PubMed,10.1111/mmi.14182,Mol Microbiol. 2018 Dec 9,bfinlay@interchange.ubc.ca,"Mouse infections with C. rodentium strains lacking individual Cpx-regulated genes showed that the chaperone/protease DegP and the disulfide bond oxidoreductase DsbA were essential for infection, but Cpx regulation of these genes did not fully account for attenuation of C. rodentium.",S L Vogt 2018,2018,5 genes,Vogt-2018-Characterization of the Citrobacter,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12943,PHI:8689,UniProt,D2TU77,GenBank,CBG90543,,,ICC168,cpxA,,,,,,PHI:8688,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,gut,two-component sensor kinase,,,,reduced virulence,,,,,,,,,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,30536519,PubMed,10.1111/mmi.14182,Mol Microbiol. 2018 Dec 9,bfinlay@interchange.ubc.ca,"Mouse infections with C. rodentium strains lacking individual Cpx-regulated genes showed that the chaperone/protease DegP and the disulfide bond oxidoreductase DsbA were essential for infection, but Cpx regulation of these genes did not fully account for attenuation of C. rodentium.",S L Vogt 2018,2018,5 genes,Vogt-2018-Characterization of the Citrobacter,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12944,PHI:8690,UniProt,D2TI49,GenBank,CBG86945,,,ICC168,degP (ROD_01651),,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,gut,periplasmic serine endoprotease DegP-like,,,,loss of pathogenicity,,,,,,,,,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,30536519,PubMed,10.1111/mmi.14182,Mol Microbiol. 2018 Dec 9,bfinlay@interchange.ubc.ca,"Mouse infections with C. rodentium strains lacking individual Cpx-regulated genes showed that the chaperone/protease DegP and the disulfide bond oxidoreductase DsbA were essential for infection, but Cpx regulation of these genes did not fully account for attenuation of C. rodentium.",S L Vogt 2018,2018,5 genes,Vogt-2018-Characterization of the Citrobacter,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12945,PHI:8691,UniProt,D2TUX9,GenBank,CBG90603,,,ICC168,dsbA (ROD_38991),,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,gut,thiol:disulfide interchange protein,,,,loss of pathogenicity,,,,,,,,,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,30536519,PubMed,10.1111/mmi.14182,Mol Microbiol. 2018 Dec 9,bfinlay@interchange.ubc.ca,"Mouse infections with C. rodentium strains lacking individual Cpx-regulated genes showed that the chaperone/protease DegP and the disulfide bond oxidoreductase DsbA were essential for infection, but Cpx regulation of these genes did not fully account for attenuation of C. rodentium.",S L Vogt 2018,2018,5 genes,Vogt-2018-Characterization of the Citrobacter,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12946,PHI:8690,UniProt,D2TI49,GenBank,CBG86945,,,ICC168,degP (ROD_01651),,PdegPΔCpxR (25-bp deletion encompassing the CpxR box in degP promoter region),,,,PHI:8688; PHI:8689,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,gut,periplasmic serine endoprotease DegP-like,,,,unaffected pathogenicity,,,,,,,,,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,altered gene expression / gene regulation,,,YVS,30536519,PubMed,10.1111/mmi.14182,Mol Microbiol. 2018 Dec 9,bfinlay@interchange.ubc.ca,"Mouse infections with C. rodentium strains lacking individual Cpx-regulated genes showed that the chaperone/protease DegP and the disulfide bond oxidoreductase DsbA were essential for infection, but Cpx regulation of these genes did not fully account for attenuation of C. rodentium.",S L Vogt 2018,2018,5 genes,Vogt-2018-Characterization of the Citrobacter,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12947,PHI:8688,UniProt,D2TU76,GenBank,CBG90542,,,ICC168,cpxR,,,,,,PHI:8690; PHI:8689,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,gut,two-component response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,30536519,PubMed,10.1111/mmi.14182,Mol Microbiol. 2018 Dec 9,bfinlay@interchange.ubc.ca,"Mouse infections with C. rodentium strains lacking individual Cpx-regulated genes showed that the chaperone/protease DegP and the disulfide bond oxidoreductase DsbA were essential for infection, but Cpx regulation of these genes did not fully account for attenuation of C. rodentium.",S L Vogt 2018,2018,5 genes,Vogt-2018-Characterization of the Citrobacter,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12948,PHI:8689,UniProt,D2TU77,GenBank,CBG90543,,,ICC168,cpxA,,,,,,PHI:8690; PHI:8688,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,gut,two-component sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,30536519,PubMed,10.1111/mmi.14182,Mol Microbiol. 2018 Dec 9,bfinlay@interchange.ubc.ca,"Mouse infections with C. rodentium strains lacking individual Cpx-regulated genes showed that the chaperone/protease DegP and the disulfide bond oxidoreductase DsbA were essential for infection, but Cpx regulation of these genes did not fully account for attenuation of C. rodentium.",S L Vogt 2018,2018,5 genes,Vogt-2018-Characterization of the Citrobacter,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12949,PHI:8692,UniProt,D2TUY0,GenBank,CBG90604,,,ICC168,rdoA (ROD_39001),,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,gut,putative regulatory protein kinase,,,,unaffected pathogenicity,,,,,,,,,,no,dithiothreitol,dithiothreitol: CHEBI:42170,,,,,promoter mutation,,,YVS,30536519,PubMed,10.1111/mmi.14182,Mol Microbiol. 2018 Dec 9,bfinlay@interchange.ubc.ca,"Mouse infections with C. rodentium strains lacking individual Cpx-regulated genes showed that the chaperone/protease DegP and the disulfide bond oxidoreductase DsbA were essential for infection, but Cpx regulation of these genes did not fully account for attenuation of C. rodentium.",S L Vogt 2018,2018,5 genes,Vogt-2018-Characterization of the Citrobacter,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12950,PHI:8693,UniProt,Q5AF03,GenBank,AOW28295,,,SC5314,GLX3,chromosome 3,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,glutathione-independent methylglyoxalase,,,,loss of pathogenicity,,,,,,,,reduced,,no,H2O2; Congo red; SDS; calcofluor white; amphotericin B,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; amphotericin B: CHEBI:2682,,,,,gene disruption; gene complementation,,,YVS,30476034,PubMed,10.1093/femsyr/foy124,FEMS Yeast Res. 2018 Nov 21,Laucamur@alumni.uv.es,"Homozygous glx3 null mutant displayed a temperature sensitive phenotype, alterations in cell wall organization, reduced biofilm formation, failure to develop germ tubes and was avirulent.",L Cabello 2018,2018,1 gene,Cabello-2018-Deletion of GLX3 in Candida albic,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12951,PHI:8695,UniProt,G4N6P6,GenBank,EHA49863,,,70-15,MoImd4 (MGG_03699),chromosome 4,,,MoPdeH,UniProt: D0ERY7; GenBank: ACX31736,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling; leaf sheath,inosine-5'-monophosphate dehydrogenase,,,purine metabolic pathway,reduced virulence,,no,,,,reduced,,reduced,,no,mycophenolic acid,mycophenolic acid: CHEBI:168396,,,,,gene deletion: full; gene complementation,,,YVS,30426699,PubMed,10.1111/mpp.12770,Mol Plant Pathol. 2018 Nov 13,zhgzhang@njau.edu.cn,"Targeted deletion of MoIMD4 resulted in reduced de novo purine biosynthesis and growth, as well as attenuated pathogenicity, which were suppressed by exogenous xanthosine monophosphate (XMP).",L Yang 2018,2018,1 gene,Yang-2018-MoImd4 mediates crosstalk between Mo,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12952,PHI:8695,UniProt,G4N6P6,GenBank,EHA49863,,,70-15,MoImd4 (MGG_03699),chromosome 4,S345AC347A point mutation,,MoPdeH,UniProt: D0ERY7; GenBank: ACX31736,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,inosine-5'-monophosphate dehydrogenase,,,purine metabolic pathway,reduced virulence,,,,,,,,reduced,,no,mycophenolic acid,mycophenolic acid: CHEBI:168396,,,,,gene mutation: characterised,,,YVS,30426699,PubMed,10.1111/mpp.12770,Mol Plant Pathol. 2018 Nov 13,zhgzhang@njau.edu.cn,"Targeted deletion of MoIMD4 resulted in reduced de novo purine biosynthesis and growth, as well as attenuated pathogenicity, which were suppressed by exogenous xanthosine monophosphate (XMP).",L Yang 2018,2018,1 gene,Yang-2018-MoImd4 mediates crosstalk between Mo,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12953,PHI:8696,UniProt,G8B820,GenBank,CCE40605,,,CDC317,CPAR2_106400,,W1370R amino acid substitution at HS2 region in CASEVO and ANDEVO strains in a homozygous form.,,,,,5480,Candida parapsilosis,,CLIB 214,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; caffeine; congo red; SDS; CdSO4; calcofluor white; caspofungin; anidulafungin; micafungin,H2O2: CHEBI:16240; caffeine: CHEBI:27732; congo red: CHEBI:34653; SDS: CHEBI:8984; CdSO4: CHEBI:50292; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; anidulafungin: CHEBI:55346; micafungin: CHEBI:600520,,,,,gene mutation,,,YVS,30429225,PubMed,10.1128/mSphere.00547-18,mSphere. 2018 Nov 14;3(6). pii: e00547-18,gacsera@gmail.com,Cross-resistance was dependent on the type of echinocandin used to generate the evolved strains and all mutant strains showed attenuated virulence in vivo and also displayed alterations in the exposure of inner cell wall components.,C Papp 2018,2018,1 gene,Papp-2018-Echinocandin-Induced Microevolution,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12954,PHI:8696,UniProt,G8B820,GenBank,CCE40605,,,CDC317,CPAR2_106400,,S656P substitution at the HS1 region in ANDEVO strain in a heterozygous form.,,,,,5480,Candida parapsilosis,,CLIB 214,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; caffeine; congo red; SDS; CdSO4; calcofluor white; caspofungin; anidulafungin; micafungin,H2O2: CHEBI:16240; caffeine: CHEBI:27732; congo red: CHEBI:34653; SDS: CHEBI:8984; CdSO4: CHEBI:50292; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; anidulafungin: CHEBI:55346; micafungin: CHEBI:600520,,,,,gene mutation,,,YVS,30429225,PubMed,10.1128/mSphere.00547-18,mSphere. 2018 Nov 14;3(6). pii: e00547-18,gacsera@gmail.com,Cross-resistance was dependent on the type of echinocandin used to generate the evolved strains and all mutant strains showed attenuated virulence in vivo and also displayed alterations in the exposure of inner cell wall components.,C Papp 2018,2018,1 gene,Papp-2018-Echinocandin-Induced Microevolution,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12955,PHI:8696,UniProt,G8B820,GenBank,CCE40605,,,CDC317,CPAR2_106400,,L703F amino acid substitution at HS3 region in MICAEVO strain in a homozygous form.,,,,,5480,Candida parapsilosis,,CLIB 214,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; caffeine; congo red; SDS; CdSO4; calcofluor white; caspofungin; anidulafungin; micafungin,H2O2: CHEBI:16240; caffeine: CHEBI:27732; congo red: CHEBI:34653; SDS: CHEBI:8984; CdSO4: CHEBI:50292; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; anidulafungin: CHEBI:55346; micafungin: CHEBI:600520,,,,,gene mutation,,,YVS,30429225,PubMed,10.1128/mSphere.00547-18,mSphere. 2018 Nov 14;3(6). pii: e00547-18,gacsera@gmail.com,Cross-resistance was dependent on the type of echinocandin used to generate the evolved strains and all mutant strains showed attenuated virulence in vivo and also displayed alterations in the exposure of inner cell wall components.,C Papp 2018,2018,1 gene,Papp-2018-Echinocandin-Induced Microevolution,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12956,PHI:8696,UniProt,G8B820,GenBank,CCE40605,,,CDC317,CPAR2_106400,,W1370R amino acid substitution at HS2 region in CASEVO and ANDEVO strains in a homozygous form.,,,,,5480,Candida parapsilosis,,CLIB 214,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; caffeine; congo red; SDS; CdSO4; calcofluor white; caspofungin; anidulafungin; micafungin,H2O2: CHEBI:16240; caffeine: CHEBI:27732; congo red: CHEBI:34653; SDS: CHEBI:8984; CdSO4: CHEBI:50292; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; anidulafungin: CHEBI:55346; micafungin: CHEBI:600520,,,,,gene mutation,,,YVS,30429225,PubMed,10.1128/mSphere.00547-18,mSphere. 2018 Nov 14;3(6). pii: e00547-18,gacsera@gmail.com,Cross-resistance was dependent on the type of echinocandin used to generate the evolved strains and all mutant strains showed attenuated virulence in vivo and also displayed alterations in the exposure of inner cell wall components.,C Papp 2018,2018,1 gene,Papp-2018-Echinocandin-Induced Microevolution,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12957,PHI:8696,UniProt,G8B820,GenBank,CCE40605,,,CDC317,CPAR2_106400,,S656P substitution at the HS1 region in ANDEVO strain in a heterozygous form.,,,,,5480,Candida parapsilosis,,CLIB 214,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; caffeine; congo red; SDS; CdSO4; calcofluor white; caspofungin; anidulafungin; micafungin,H2O2: CHEBI:16240; caffeine: CHEBI:27732; congo red: CHEBI:34653; SDS: CHEBI:8984; CdSO4: CHEBI:50292; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; anidulafungin: CHEBI:55346; micafungin: CHEBI:600520,,,,,gene mutation,,,YVS,30429225,PubMed,10.1128/mSphere.00547-18,mSphere. 2018 Nov 14;3(6). pii: e00547-18,gacsera@gmail.com,Cross-resistance was dependent on the type of echinocandin used to generate the evolved strains and all mutant strains showed attenuated virulence in vivo and also displayed alterations in the exposure of inner cell wall components.,C Papp 2018,2018,1 gene,Papp-2018-Echinocandin-Induced Microevolution,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12958,PHI:8696,UniProt,G8B820,GenBank,CCE40605,,,CDC317,CPAR2_106400,,L703F amino acid substitution at HS3 region in MICAEVO strain in a homozygous form.,,,,,5480,Candida parapsilosis,,CLIB 214,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; caffeine; congo red; SDS; CdSO4; calcofluor white; caspofungin; anidulafungin; micafungin,H2O2: CHEBI:16240; caffeine: CHEBI:27732; congo red: CHEBI:34653; SDS: CHEBI:8984; CdSO4: CHEBI:50292; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; anidulafungin: CHEBI:55346; micafungin: CHEBI:600520,,,,,gene mutation,,,YVS,30429225,PubMed,10.1128/mSphere.00547-18,mSphere. 2018 Nov 14;3(6). pii: e00547-18,gacsera@gmail.com,Cross-resistance was dependent on the type of echinocandin used to generate the evolved strains and all mutant strains showed attenuated virulence in vivo and also displayed alterations in the exposure of inner cell wall components.,C Papp 2018,2018,1 gene,Papp-2018-Echinocandin-Induced Microevolution,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12959,PHI:8697,UniProt,C6ZEZ6,GenBank,ACF39937,,,81278ZB15,AvrPiz-t,chromosome 7,lysine-free (LF-AvrPiz-t) mutant,,,,,318829,Magnaporthe oryzae,,RB22,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants; gene mutation,,,YVS,30548752,PubMed,10.1111/mpp.12779,Mol Plant Pathol. 2018 Dec 12,wang.620@osu.edu,Lysine residues of AvrPiz-t were essential for the suppression of plant basal defense.,P Bai 2018,2018,1 gene,Bai-2018-Role of lysine residues of the Magnap,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12960,PHI:8697,UniProt,C6ZEZ6,GenBank,ACF39937,,,81278ZB15,AvrPiz-t,chromosome 7,lysine-free (LF-AvrPiz-t) mutant,,,,,318829,Magnaporthe oryzae,,RB22,blast (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants; gene mutation,,,YVS,30548752,PubMed,10.1111/mpp.12779,Mol Plant Pathol. 2018 Dec 12,wang.620@osu.edu,Lysine residues of AvrPiz-t were essential for the suppression of plant basal defense.,P Bai 2018,2018,1 gene,Bai-2018-Role of lysine residues of the Magnap,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12961,PHI:8697,UniProt,C6ZEZ6,GenBank,ACF39937,,,81278ZB15,AvrPiz-t,chromosome 7,,,,,,318829,Magnaporthe oryzae,,RB22,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30548752,PubMed,10.1111/mpp.12779,Mol Plant Pathol. 2018 Dec 12,wang.620@osu.edu,Lysine residues of AvrPiz-t were essential for the suppression of plant basal defense.,P Bai 2018,2018,1 gene,Bai-2018-Role of lysine residues of the Magnap,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12962,PHI:8697,UniProt,C6ZEZ6,GenBank,ACF39937,,,81278ZB15,AvrPiz-t,chromosome 7,,,,,,318829,Magnaporthe oryzae,,RB22,blast (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30548752,PubMed,10.1111/mpp.12779,Mol Plant Pathol. 2018 Dec 12,wang.620@osu.edu,Lysine residues of AvrPiz-t were essential for the suppression of plant basal defense.,P Bai 2018,2018,1 gene,Bai-2018-Role of lysine residues of the Magnap,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12963,PHI:8698,,no data found,,,,,,afpA,,,,,,PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12964,PHI:8699,,no data found,,,,,,afpG,,,,,,PHI:8698; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12965,PHI:8700,,no data found,,,,,,afpB,,,,,,PHI:8698; PHI:8699; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12966,PHI:8701,,no data found,,,,,,afpC,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12967,PHI:8702,,no data found,,,,,,afpU,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12968,PHI:8703,,no data found,,,,,,afpD,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12969,PHI:8704,,no data found,,,,,,afpE,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12970,PHI:8705,,no data found,,,,,,afpF,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12971,PHI:8706,,no data found,,,,,,afpH,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12972,PHI:8707,,no data found,,,,,,afpP,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12973,PHI:8708,,no data found,,,,,,afpI,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8709; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12974,PHI:8709,,no data found,,,,,,afpJ,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8710; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12975,PHI:8710,,no data found,,,,,,afpK,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8711; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12976,PHI:8711,,no data found,,,,,,afpL,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8712; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12977,PHI:8712,,no data found,,,,,,afpA2,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12978,PHI:8713,UniProt,Q8XBV2,GenBank,EGT68086,,,C227-11,stx2,,,,,,PHI:8698; PHI:8699; PHI:8700; PHI:8701; PHI:8702; PHI:8703; PHI:8704; PHI:8705; PHI:8706; PHI:8707; PHI:8708; PHI:8709; PHI:8710; PHI:8711; PHI:8712,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,Shiga toxin 2 subunit A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12979,PHI:8698,,no data found,,,,,,afpA,,,,,,PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12980,PHI:8713,UniProt,Q8XBV2,GenBank,EGT68086,,,C227-11,stx2,,,,,,PHI:8698,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,Shiga toxin 2 subunit A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12981,PHI:8714,,no data found,,,,,,afpR,,,,,,PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,AraC-like regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12982,PHI:8713,UniProt,Q8XBV2,GenBank,EGT68086,,,C227-11,stx2,,,,,,PHI:8714,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,Shiga toxin 2 subunit A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12983,PHI:8712,,no data found,,,,,,afpA2,,,,,,PHI:8713,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,aggregate-forming pili protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12984,PHI:8713,UniProt,Q8XBV2,GenBank,EGT68086,,,C227-11,stx2,,,,,,PHI:8712,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,Shiga toxin 2 subunit A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12985,PHI:8713,UniProt,Q8XBV2,GenBank,EGT68086,,,C227-11,stx2,,,,,,,562,Escherichia coli,,12-05829,hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,Shiga toxin 2 subunit A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30514915,PubMed,10.1038/s41426-018-0209-8,Emerg Microbes Infect. 2018 Dec 5;7(1):203,fliegera@rki.de,"The deletion of the afp operon, afpA, or a nearby gene (afpR) encoding an AraC-like regulator, but not afpA2, led to a loss of pilin production, piliation, bacterial autoaggregation, and importantly, a>80% reduction in adhesion and cytotoxicity toward epithelial cells.",C Lang 2018,2018,17 genes,Lang-2018-Novel type of pilus associated with,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12986,PHI:8715,UniProt,P87024,GenBank,BAA19594,,,,SKN1,,PTEF1-SKN1 (DNA fragment containing ORF and terminator cloned behind TEF1 promoter),,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),FaDu cell line,,,oral epithelial cell,beta-glucan synthesis-associated protein,,,"β-1,6-glucan biosynthesis",reduced virulence,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); SDS,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30507002,PubMed,10.1111/mmi.14176,Mol Microbiol. 2018 Dec 3,jlsang@bnu.edu.cn,"While deleting KRE6 or SKN1 had no obvious phenotypic consequence, deleting both caused slow growth, cell separation failure, cell wall abnormalities, diminished hyphal growth, poor biofilm formation, and loss of virulence in mice.",Q Han 2018,2018,2 genes,"Han-2018-Blocking beta-1,6-glucan synthesis by",BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12987,PHI:8715,UniProt,P87024,GenBank,BAA19594,,,,SKN1,,PTDH3-SKN1 (DNA fragment containing ORF and terminator cloned behind TDH3 promoter),,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),FaDu cell line,,,oral epithelial cell,beta-glucan synthesis-associated protein,,,"β-1,6-glucan biosynthesis",reduced virulence,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); SDS,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30507002,PubMed,10.1111/mmi.14176,Mol Microbiol. 2018 Dec 3,jlsang@bnu.edu.cn,"While deleting KRE6 or SKN1 had no obvious phenotypic consequence, deleting both caused slow growth, cell separation failure, cell wall abnormalities, diminished hyphal growth, poor biofilm formation, and loss of virulence in mice.",Q Han 2018,2018,2 genes,"Han-2018-Blocking beta-1,6-glucan synthesis by",BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12988,PHI:8715,UniProt,P87024,GenBank,BAA19594,,,,SKN1,,PTEF1-SKN1 (DNA fragment containing ORF and terminator cloned behind TEF1 promoter),,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),MS1 cell line,,,pancreatic islet cell,beta-glucan synthesis-associated protein,,,"β-1,6-glucan biosynthesis",reduced virulence,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); SDS,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30507002,PubMed,10.1111/mmi.14176,Mol Microbiol. 2018 Dec 3,jlsang@bnu.edu.cn,"While deleting KRE6 or SKN1 had no obvious phenotypic consequence, deleting both caused slow growth, cell separation failure, cell wall abnormalities, diminished hyphal growth, poor biofilm formation, and loss of virulence in mice.",Q Han 2018,2018,2 genes,"Han-2018-Blocking beta-1,6-glucan synthesis by",BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12989,PHI:8715,UniProt,P87024,GenBank,BAA19594,,,,SKN1,,PTDH3-SKN1 (DNA fragment containing ORF and terminator cloned behind TDH3 promoter),,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),MS1 cell line,,,pancreatic islet cell,beta-glucan synthesis-associated protein,,,"β-1,6-glucan biosynthesis",reduced virulence,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); SDS,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30507002,PubMed,10.1111/mmi.14176,Mol Microbiol. 2018 Dec 3,jlsang@bnu.edu.cn,"While deleting KRE6 or SKN1 had no obvious phenotypic consequence, deleting both caused slow growth, cell separation failure, cell wall abnormalities, diminished hyphal growth, poor biofilm formation, and loss of virulence in mice.",Q Han 2018,2018,2 genes,"Han-2018-Blocking beta-1,6-glucan synthesis by",BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12990,PHI:8715,UniProt,P87024,GenBank,BAA19594,,,,SKN1,,PTEF1-SKN1 (DNA fragment containing ORF and terminator cloned behind TEF1 promoter),,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,beta-glucan synthesis-associated protein,,,"β-1,6-glucan biosynthesis",reduced virulence,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); SDS,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30507002,PubMed,10.1111/mmi.14176,Mol Microbiol. 2018 Dec 3,jlsang@bnu.edu.cn,"While deleting KRE6 or SKN1 had no obvious phenotypic consequence, deleting both caused slow growth, cell separation failure, cell wall abnormalities, diminished hyphal growth, poor biofilm formation, and loss of virulence in mice.",Q Han 2018,2018,2 genes,"Han-2018-Blocking beta-1,6-glucan synthesis by",BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12991,PHI:8715,UniProt,P87024,GenBank,BAA19594,,,,SKN1,,PTDH3-SKN1 (DNA fragment containing ORF and terminator cloned behind TDH3 promoter),,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,beta-glucan synthesis-associated protein,,,"β-1,6-glucan biosynthesis",reduced virulence,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); SDS,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30507002,PubMed,10.1111/mmi.14176,Mol Microbiol. 2018 Dec 3,jlsang@bnu.edu.cn,"While deleting KRE6 or SKN1 had no obvious phenotypic consequence, deleting both caused slow growth, cell separation failure, cell wall abnormalities, diminished hyphal growth, poor biofilm formation, and loss of virulence in mice.",Q Han 2018,2018,2 genes,"Han-2018-Blocking beta-1,6-glucan synthesis by",BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12992,PHI:8716,UniProt,P87023,GenBank,BAA19593,,,,KRE6,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,"β-1,6-glucan synthase",,,"β-1,6-glucan biosynthesis",unaffected pathogenicity,,,,,,,,reduced; aberrant,,no,calcofluor white (CFW); Congo red (CR); SDS,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30507002,PubMed,10.1111/mmi.14176,Mol Microbiol. 2018 Dec 3,jlsang@bnu.edu.cn,"While deleting KRE6 or SKN1 had no obvious phenotypic consequence, deleting both caused slow growth, cell separation failure, cell wall abnormalities, diminished hyphal growth, poor biofilm formation, and loss of virulence in mice.",Q Han 2018,2018,2 genes,"Han-2018-Blocking beta-1,6-glucan synthesis by",BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12993,PHI:8715,UniProt,P87024,GenBank,BAA19594,,,,SKN1,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,beta-glucan synthesis-associated protein,,,"β-1,6-glucan biosynthesis",unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white (CFW); Congo red (CR); SDS,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30507002,PubMed,10.1111/mmi.14176,Mol Microbiol. 2018 Dec 3,jlsang@bnu.edu.cn,"While deleting KRE6 or SKN1 had no obvious phenotypic consequence, deleting both caused slow growth, cell separation failure, cell wall abnormalities, diminished hyphal growth, poor biofilm formation, and loss of virulence in mice.",Q Han 2018,2018,2 genes,"Han-2018-Blocking beta-1,6-glucan synthesis by",BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12994,PHI:8716,UniProt,P87023,GenBank,BAA19593,,,,KRE6,,,,,,PHI:8715,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,"β-1,6-glucan synthase",,,"β-1,6-glucan biosynthesis",loss of pathogenicity,,,,,,,,reduced; aberrant,,no,calcofluor white (CFW); Congo red (CR); SDS,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30507002,PubMed,10.1111/mmi.14176,Mol Microbiol. 2018 Dec 3,jlsang@bnu.edu.cn,"While deleting KRE6 or SKN1 had no obvious phenotypic consequence, deleting both caused slow growth, cell separation failure, cell wall abnormalities, diminished hyphal growth, poor biofilm formation, and loss of virulence in mice.",Q Han 2018,2018,2 genes,"Han-2018-Blocking beta-1,6-glucan synthesis by",BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12995,PHI:8715,UniProt,P87024,GenBank,BAA19594,,,,SKN1,,,,,,PHI:8716,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,beta-glucan synthesis-associated protein,,,"β-1,6-glucan biosynthesis",loss of pathogenicity,,,,,,,,reduced; aberrant,,no,calcofluor white (CFW); Congo red (CR); SDS,calcoflour white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30507002,PubMed,10.1111/mmi.14176,Mol Microbiol. 2018 Dec 3,jlsang@bnu.edu.cn,"While deleting KRE6 or SKN1 had no obvious phenotypic consequence, deleting both caused slow growth, cell separation failure, cell wall abnormalities, diminished hyphal growth, poor biofilm formation, and loss of virulence in mice.",Q Han 2018,2018,2 genes,"Han-2018-Blocking beta-1,6-glucan synthesis by",BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12996,PHI:8717,UniProt,Q874A5,GenBank,AAO48438,,,,PePacC,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,pH-response transcription factor,,,patulin biosynthesis pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12997,PHI:8718,UniProt,A0A0A2J5T2,GenBank,KGO54114,,,MD-8,PeCrt,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,calreticulin,,,patulin biosynthesis pathway,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12998,PHI:8719,UniProt,A0A0A2JPI4,GenBank,KGO56731,,,MD-8,PePpi,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,peptidyl-prolyl cis-trans isomerase,,,patulin biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 12999,PHI:8720,UniProt,A0A0A2HZI5,GenBank,KGO52578,,,MD-8,PeImp,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,immunogenic protein,,,patulin biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13000,PHI:8721,,no data found,,,,,,PePrdx6,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,peroxiredoxin-6,,,patulin biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13001,PHI:8722,UniProt,A0A0A2JZB1,GenBank,KGO57535,,,MD-8,PeCat,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,catalase,,,patulin biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13002,PHI:8723,UniProt,A0A0A2L0F6,GenBank,KGO49947,,,MD-8,PeTrx,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,thioredoxin,,,patulin biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13003,PHI:8724,UniProt,A0A0A2JZB1,GenBank,KGO57535,,,MD-8,PeSat,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,sulfate adenylyltransferase,,,patulin biosynthesis pathway,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13004,PHI:8725,,no data found,,,,,,PeGod,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,glucose oxidase,,,patulin biosynthesis pathway,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13005,PHI:8717,UniProt,Q874A5,GenBank,AAO48438,,,,PePacC,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: Pear),cv. Pyrus bretschneideri Rehd,,,fruit,pH-response transcription factor,,,patulin biosynthesis pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13006,PHI:8718,UniProt,A0A0A2J5T2,GenBank,KGO54114,,,MD-8,PeCrt,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: Pear),cv. Pyrus bretschneideri Rehd,,,fruit,calreticulin,,,patulin biosynthesis pathway,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13007,PHI:8719,UniProt,A0A0A2JPI4,GenBank,KGO56731,,,MD-8,PePpi,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: Pear),cv. Pyrus bretschneideri Rehd,,,fruit,peptidyl-prolyl cis-trans isomerase,,,patulin biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13008,PHI:8720,UniProt,A0A0A2HZI5,GenBank,KGO52578,,,MD-8,PeImp,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: Pear),cv. Pyrus bretschneideri Rehd,,,fruit,immunogenic protein,,,patulin biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13009,PHI:8721,,no data found,,,,,,PePrdx6,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: Pear),cv. Pyrus bretschneideri Rehd,,,fruit,peroxiredoxin-6,,,patulin biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13010,PHI:8722,UniProt,A0A0A2JZB1,GenBank,KGO57535,,,MD-8,PeCat,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: Pear),cv. Pyrus bretschneideri Rehd,,,fruit,catalase,,,patulin biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13011,PHI:8723,UniProt,A0A0A2L0F6,GenBank,KGO49947,,,MD-8,PeTrx,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: Pear),cv. Pyrus bretschneideri Rehd,,,fruit,thioredoxin,,,patulin biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13012,PHI:8724,UniProt,A0A0A2JZB1,GenBank,KGO57535,,,MD-8,PeSat,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: Pear),cv. Pyrus bretschneideri Rehd,,,fruit,sulfate adenylyltransferase,,,patulin biosynthesis pathway,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13013,PHI:8725,,no data found,,,,,,PeGod,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay; carcinogenesis,eudicots,23211,Pyrus communis (related: Pear),cv. Pyrus bretschneideri Rehd,,,fruit,glucose oxidase,,,patulin biosynthesis pathway,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30370586,PubMed,10.1111/1462-2920.14453,Environ Microbiol. 2018 Nov;20(11):4063-4078,tsp@ibcas.ac.cn,"PePacC played an important role in patulin biosynthesis via limiting expressions of the genes in the cluster, and in pathogenesis via mediating virulence factors such as glucose oxidase (PeGOD), PeCRT and PeSAT.",Y Chen 2018,2018,9 genes,Chen-2018-The pH-responsive PacC transcription,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13014,PHI:8726,UniProt,Q7CPD5,GenBank,AAL22819,,,LT2,tatC,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node; spleen,Sec-independent protein translocase,,,,reduced virulence,,,,,,,,,,no,streptomycin,streptomycin: CHEBI:17076,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13015,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,PHI:8726,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; deoxycholate,streptomycin: CHEBI:17076; deoxycholate: CHEBI:23614,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13016,PHI:8726,UniProt,Q7CPD5,GenBank,AAL22819,,,LT2,tatC,,,,,,PHI:8727,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node,Sec-independent protein translocase,,,,reduced virulence,,,,,,,,,,no,streptomycin; deoxycholate,streptomycin: CHEBI:17076; deoxycholate: CHEBI:23614,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13017,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,PHI:8728,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node,secretion system apparatus protein,,,,unaffected pathogenicity,,,,,,,,,,no,streptomycin; NaCl,streptomycin: CHEBI:17076; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13018,PHI:8728,UniProt,P33772,GenBank,AAL21344,,,LT2,amiA,,,,,,PHI:8727,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node; spleen,N-acetylmuramoyl-L-alanine amidase,,,,unaffected pathogenicity,,,,,,,,,,no,streptomycin; NaCl,streptomycin: CHEBI:17076; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13019,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node; spleen,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; NaCl,streptomycin: CHEBI:17076; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13020,PHI:8729,UniProt,Q8ZMB9,GenBank,AAL21867,,,LT2,amiC,,,,,,PHI:8727,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node; spleen,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin; NaCl,streptomycin: CHEBI:17076; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13021,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,PHI:8728; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node; spleen,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; colestimide; deoxycholate; NaCl; polymixin B,streptomycin: CHEBI:17076; colestimide: CHEBI:31428; deoxycholate: CHEBI:23614; NaCl: CHEBI:26710; polymixin B: CHEBI:8310,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13022,PHI:8728,UniProt,P33772,GenBank,AAL21344,,,LT2,amiA,,,,,,PHI:8727; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node; spleen,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin; colestimide; deoxycholate; NaCl; polymixin B,streptomycin: CHEBI:17076; colestimide: CHEBI:31428; deoxycholate: CHEBI:23614; NaCl: CHEBI:26710; polymixin B: CHEBI:8310,,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13023,PHI:8729,UniProt,Q8ZMB9,GenBank,AAL21867,,,LT2,amiC,,,,,,PHI:8727; PHI:8728,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node; spleen,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin; colestimide; deoxycholate; NaCl; polymixin B,streptomycin: CHEBI:17076; colestimide: CHEBI:31428; deoxycholate: CHEBI:23614; NaCl: CHEBI:26710; polymixin B: CHEBI:8310,,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13024,PHI:8730,UniProt,P35672,GenBank,AAL21778,,,LT2,invG,,,,,,PHI:8727; PHI:8728; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,outer membrane invasion protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13025,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,PHI:8730; PHI:8728; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13026,PHI:8728,UniProt,P33772,GenBank,AAL21344,,,LT2,amiA,,,,,,PHI:8730; PHI:8727; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13027,PHI:8729,UniProt,Q8ZMB9,GenBank,AAL21867,,,LT2,amiC,,,,,,PHI:8730; PHI:8727; PHI:8728,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13028,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,PHI:8730,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13029,PHI:8730,UniProt,P35672,GenBank,AAL21778,,,LT2,invG,,,,,,PHI:8727,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,outer membrane invasion protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13030,PHI:8728,UniProt,P33772,GenBank,AAL21344,,,LT2,amiA,,,,,,PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin; deoxycholate; magainin 2,"streptomycin: CHEBI:17076; deoxycholate: CHEBI:23614, 2; magainin: CHEBI:80190",,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13031,PHI:8729,UniProt,Q8ZMB9,GenBank,AAL21867,,,LT2,amiC,,,,,,PHI:8728,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin; deoxycholate; magainin 2,"streptomycin: CHEBI:17076; deoxycholate: CHEBI:23614, 2; magainin: CHEBI:80190",,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13032,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,PHI:8731,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13033,PHI:8731,UniProt,P40729,GenBank,AAL20829,,,LT2,flhA,,,,,,PHI:8727,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,flagellar biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13034,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,PHI:8731; PHI:8728; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13035,PHI:8731,UniProt,P40729,GenBank,AAL20829,,,LT2,flhA,,,,,,PHI:8727; PHI:8728; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,flagellar biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13036,PHI:8728,UniProt,P33772,GenBank,AAL21344,,,LT2,amiA,,,,,,PHI:8727; PHI:8731; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13037,PHI:8729,UniProt,Q8ZMB9,GenBank,AAL21867,,,LT2,amiC,,,,,,PHI:8727; PHI:8731; PHI:8728,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin; dextran sulfate sodium,streptomycin: CHEBI:17076; dextran sulfate sodium: CHEBI:116735,,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13038,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,PHI:8732,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,streptomycin,streptomycin: CHEBI:17076,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13039,PHI:8732,UniProt,P0A2D5,GenBank,AAL20832,,,LT2,cheY,,,,,,PHI:8727,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,chemotaxis regulator protein,,,,reduced virulence,,,,,,,,,,no,streptomycin,streptomycin: CHEBI:17076,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13040,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,PHI:8732; PHI:8728; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,streptomycin,streptomycin: CHEBI:17076,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13041,PHI:8732,UniProt,P0A2D5,GenBank,AAL20832,,,LT2,cheY,,,,,,PHI:8727; PHI:8728; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,chemotaxis regulator protein,,,,reduced virulence,,,,,,,,,,no,streptomycin,streptomycin: CHEBI:17076,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13042,PHI:8728,UniProt,P33772,GenBank,AAL21344,,,LT2,amiA,,,,,,PHI:8727; PHI:8732; PHI:8729,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin,streptomycin: CHEBI:17076,,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13043,PHI:8729,UniProt,Q8ZMB9,GenBank,AAL21867,,,LT2,amiC,,,,,,PHI:8727; PHI:8732; PHI:8728,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,streptomycin,streptomycin: CHEBI:17076,,,,,gene mutation; gene complementation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13044,PHI:8727,UniProt,P74856,GenBank,AAL20338,,,LT2,ssaV,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,streptomycin; colestimide; deoxycholate; NaCl; polymixin B,streptomycin: CHEBI:17076; colestimide: CHEBI:31428; deoxycholate: CHEBI:23614; NaCl: CHEBI:26710; polymixin B: CHEBI:8310,,,,,gene mutation,,,YVS,30379938,PubMed,10.1371/journal.ppat.1007391,PLoS Pathog. 2018 Oct 31;14(10):e1007391,mikit@pharm.kitasato-u.ac.jp,"Tat and the Tat-exported amidases, AmiA and AmiC, were required for S. Tm luminal fitness in the inflamed gut.",M Fujimoto 2018,2018,7 genes,Fujimoto-2018-Tat-exported peptidoglycan amida,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13045,PHI:8733,UniProt,A0A384JM90,GenBank,ATZ51715,,,B05.10,BcKDM1 (Bcin07g03050),BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,putative H3K36/K9 demethylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; menadione; SDS; ascorbic acid,H2O2: CHEBI:16240; menadione: CHEBI:28869; SDS: CHEBI:8984; ascorbic acid: CHEBI:22652,,,,,gene deletion: full; gene complementation,,,YVS,30445217,PubMed,10.1016/j.fgb.2018.11.003,Fungal Genet Biol. 2018 Nov 13;123:14-24,Julia.schumacher@wwu.de,"Targeted mutagenesis of bckdm1 confirmed the gene-phenotype linkage and indicated that BcKDM1, despite its role in virulence (critical for penetration), was required for coping with excessive light, oxidative stress and for proper expression of light-responsive genes and photomorphogenesis.",J Schumacher 2018,2018,1 gene,Schumacher-2018-The putative H3K36 demethylase,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13046,PHI:8733,UniProt,A0A384JM90,GenBank,ATZ51715,,,B05.10,BcKDM1 (Bcin07g03050),BCIN07,H360A,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,putative H3K36/K9 demethylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; menadione; SDS; ascorbic acid,H2O2: CHEBI:16240; menadione: CHEBI:28869; SDS: CHEBI:8984; ascorbic acid: CHEBI:22652,,,,,gene mutation: characterised,,,YVS,30445217,PubMed,10.1016/j.fgb.2018.11.003,Fungal Genet Biol. 2018 Nov 13;123:14-24,Julia.schumacher@wwu.de,"Targeted mutagenesis of bckdm1 confirmed the gene-phenotype linkage and indicated that BcKDM1, despite its role in virulence (critical for penetration), was required for coping with excessive light, oxidative stress and for proper expression of light-responsive genes and photomorphogenesis.",J Schumacher 2018,2018,1 gene,Schumacher-2018-The putative H3K36 demethylase,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13047,PHI:8733,UniProt,A0A384JM90,GenBank,ATZ51715,,,B05.10,BcKDM1 (Bcin07g03050),BCIN07,mutant expressing a truncated protein of 991 amino acids,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. 90598,,,leaf,putative H3K36/K9 demethylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; menadione; SDS; ascorbic acid,H2O2: CHEBI:16240; menadione: CHEBI:28869; SDS: CHEBI:8984; ascorbic acid: CHEBI:22652,,,,,gene deletion: partial,,,YVS,30445217,PubMed,10.1016/j.fgb.2018.11.003,Fungal Genet Biol. 2018 Nov 13;123:14-24,Julia.schumacher@wwu.de,"Targeted mutagenesis of bckdm1 confirmed the gene-phenotype linkage and indicated that BcKDM1, despite its role in virulence (critical for penetration), was required for coping with excessive light, oxidative stress and for proper expression of light-responsive genes and photomorphogenesis.",J Schumacher 2018,2018,1 gene,Schumacher-2018-The putative H3K36 demethylase,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13048,PHI:8734,UniProt,G4MTG9,GenBank,EHA54720,,,70-15,MoLeu1 (MGG_01553),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,3-isopropylmalate dehydratase,,,leucine biosynthesis,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30357439,PubMed,10.1007/s00253-018-9456-9,Appl Microbiol Biotechnol. 2019 Jan;103(1):327-337,wangzh@fafu.edu.cn,"Targeted gene deletion of MoLEU1 led to leucine auxotrophy, and phenotypic analysis of the generated ΔMoleu1 strain revealed that MoLeu1-mediated leucine biosynthesis was required for vegetative growth, asexual development and pathogenesis of M.oryzae.",W Tang 2018,2018,1 gene,Tang-2018-Isopropylmalate isomerase MoLeu1 orc,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13049,PHI:8734,UniProt,G4MTG9,GenBank,EHA54720,,,70-15,MoLeu1 (MGG_01553),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,3-isopropylmalate dehydratase,,,leucine biosynthesis,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30357439,PubMed,10.1007/s00253-018-9456-9,Appl Microbiol Biotechnol. 2019 Jan;103(1):327-337,wangzh@fafu.edu.cn,"Targeted gene deletion of MoLEU1 led to leucine auxotrophy, and phenotypic analysis of the generated ΔMoleu1 strain revealed that MoLeu1-mediated leucine biosynthesis was required for vegetative growth, asexual development and pathogenesis of M.oryzae.",W Tang 2018,2018,1 gene,Tang-2018-Isopropylmalate isomerase MoLeu1 orc,BATCH_088B,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13050,PHI:8735,UniProt,K9FTS6,GenBank,EKV06178,,,PHI26,Hog1 (PDIG_79560),,,,,,,36651,Penicillium digitatum,1170229,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,mitogen-activated protein kinase,,,mitogen-activated protein kinases (MAPK) pathway,reduced virulence,,,,,,,,aberrant,,no,NaCl; D-sorbitol; fludioxonil; calcofluor white (CFW); congo red (CR); thiabendazole (TBZ); imazalil (IMZ); iprodione (IPD),NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; fludioxonil CAS no.: CAS:131341-86-1; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; thiabendazole (TBZ): CHEBI:45979; imazalil (IMZ): CHEBI:81927; iprodione (IPD): CHEBI:28909,,,,,gene deletion: full,,,YVS,30579886,PubMed,10.1016/j.fgb.2018.12.006,Fungal Genet Biol. 2018 Dec 21;124:17-28,jmarcos@iata.csic.es,"Mutants Δslt2 and Δkss1 showed a strong reduction in virulence, whereas Δhog1 was the least affected, and none sporulated during infection.",M Gandia 2018,2018,3 genes,"Gandia-2018-Differential roles, crosstalk and",BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13051,PHI:8736,UniProt,K9FDB7,GenBank,EKV07229,,,PHI26,Kss1 (PDIG_75030),,,,,,,36651,Penicillium digitatum,1170229,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,mitogen-activated protein kinase,,,mitogen-activated protein kinases (MAPK) pathway,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl; D-sorbitol; fludioxonil; calcofluor white (CFW); congo red (CR); thiabendazole (TBZ); imazalil (IMZ); iprodione (IPD),NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; fludioxonil CAS no.: CAS:131341-86-1; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; thiabendazole (TBZ): CHEBI:45979; imazalil (IMZ): CHEBI:81927; iprodione (IPD): CHEBI:28909,,,,,gene deletion: full,,,YVS,30579886,PubMed,10.1016/j.fgb.2018.12.006,Fungal Genet Biol. 2018 Dec 21;124:17-28,jmarcos@iata.csic.es,"Mutants Δslt2 and Δkss1 showed a strong reduction in virulence, whereas Δhog1 was the least affected, and none sporulated during infection.",M Gandia 2018,2018,3 genes,"Gandia-2018-Differential roles, crosstalk and",BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13052,PHI:8737,UniProt,K9FXQ2,GenBank,EKV07468,,,PHI26,Slt2 (PDIG_73290),,,,,,,36651,Penicillium digitatum,1170229,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,mitogen-activated protein kinase,,,mitogen-activated protein kinases (MAPK) pathway,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; D-sorbitol; fludioxonil; calcofluor white (CFW); congo red (CR); thiabendazole (TBZ); imazalil (IMZ); iprodione (IPD),NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; fludioxonil CAS no.: CAS:131341-86-1; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; thiabendazole (TBZ): CHEBI:45979; imazalil (IMZ): CHEBI:81927; iprodione (IPD): CHEBI:28909,,,,,gene deletion: full; gene complementation,,,YVS,30579886,PubMed,10.1016/j.fgb.2018.12.006,Fungal Genet Biol. 2018 Dec 21;124:17-28,jmarcos@iata.csic.es,"Mutants Δslt2 and Δkss1 showed a strong reduction in virulence, whereas Δhog1 was the least affected, and none sporulated during infection.",M Gandia 2018,2018,3 genes,"Gandia-2018-Differential roles, crosstalk and",BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13053,PHI:8735,UniProt,K9FTS6,GenBank,EKV06178,,,PHI26,Hog1 (PDIG_79560),,,,,,,36651,Penicillium digitatum,1170229,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Clemenules,,,fruit,mitogen-activated protein kinase,,,mitogen-activated protein kinases (MAPK) pathway,unaffected pathogenicity,,,,,,,,aberrant,,no,NaCl; D-sorbitol; fludioxonil; calcofluor white (CFW); congo red (CR); thiabendazole (TBZ); imazalil (IMZ); iprodione (IPD),NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; fludioxonil CAS no.: CAS:131341-86-1; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; thiabendazole (TBZ): CHEBI:45979; imazalil (IMZ): CHEBI:81927; iprodione (IPD): CHEBI:28909,,,,,gene deletion: full,,,YVS,30579886,PubMed,10.1016/j.fgb.2018.12.006,Fungal Genet Biol. 2018 Dec 21;124:17-28,jmarcos@iata.csic.es,"Mutants Δslt2 and Δkss1 showed a strong reduction in virulence, whereas Δhog1 was the least affected, and none sporulated during infection.",M Gandia 2018,2018,3 genes,"Gandia-2018-Differential roles, crosstalk and",BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13054,PHI:8736,UniProt,K9FDB7,GenBank,EKV07229,,,PHI26,Kss1 (PDIG_75030),,,,,,,36651,Penicillium digitatum,1170229,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Clemenules,,,fruit,mitogen-activated protein kinase,,,mitogen-activated protein kinases (MAPK) pathway,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl; D-sorbitol; fludioxonil; calcofluor white (CFW); congo red (CR); thiabendazole (TBZ); imazalil (IMZ); iprodione (IPD),NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; fludioxonil CAS no.: CAS:131341-86-1; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; thiabendazole (TBZ): CHEBI:45979; imazalil (IMZ): CHEBI:81927; iprodione (IPD): CHEBI:28909,,,,,gene deletion: full,,,YVS,30579886,PubMed,10.1016/j.fgb.2018.12.006,Fungal Genet Biol. 2018 Dec 21;124:17-28,jmarcos@iata.csic.es,"Mutants Δslt2 and Δkss1 showed a strong reduction in virulence, whereas Δhog1 was the least affected, and none sporulated during infection.",M Gandia 2018,2018,3 genes,"Gandia-2018-Differential roles, crosstalk and",BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13055,PHI:8737,UniProt,K9FXQ2,GenBank,EKV07468,,,PHI26,Slt2 (PDIG_73290),,,,,,,36651,Penicillium digitatum,1170229,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Clemenules,,,fruit,mitogen-activated protein kinase,,,mitogen-activated protein kinases (MAPK) pathway,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; D-sorbitol; fludioxonil; calcofluor white (CFW); congo red (CR); thiabendazole (TBZ); imazalil (IMZ); iprodione (IPD),NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; fludioxonil CAS no.: CAS:131341-86-1; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; thiabendazole (TBZ): CHEBI:45979; imazalil (IMZ): CHEBI:81927; iprodione (IPD): CHEBI:28909,,,,,gene deletion: full; gene complementation,,,YVS,30579886,PubMed,10.1016/j.fgb.2018.12.006,Fungal Genet Biol. 2018 Dec 21;124:17-28,jmarcos@iata.csic.es,"Mutants Δslt2 and Δkss1 showed a strong reduction in virulence, whereas Δhog1 was the least affected, and none sporulated during infection.",M Gandia 2018,2018,3 genes,"Gandia-2018-Differential roles, crosstalk and",BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13056,PHI:8738,UniProt,A0A0K0GQN3,GenBank,ACD61453,,,PXO99A,XopN,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30631333,PubMed,10.3389/fpls.2018.01857,Front Plant Sci. 2018 Dec 12;9:1857,yangbi@missouri.edu,"The triple mutant of the X. oryzae pv. oryzae strain PXO99A lacking XopZ, XopN and XopV showed additively reduced virulence.",J Long 2018,2018,3 genes,Long-2018-Non-TAL Effectors From Xanthomonas o,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13057,PHI:8739,UniProt,G7TBH8,,,,,PXO99A,XopV,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30631333,PubMed,10.3389/fpls.2018.01857,Front Plant Sci. 2018 Dec 12;9:1857,yangbi@missouri.edu,"The triple mutant of the X. oryzae pv. oryzae strain PXO99A lacking XopZ, XopN and XopV showed additively reduced virulence.",J Long 2018,2018,3 genes,Long-2018-Non-TAL Effectors From Xanthomonas o,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13058,PHI:8740,UniProt,G7TFJ1,,,,,,XopZ,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30631333,PubMed,10.3389/fpls.2018.01857,Front Plant Sci. 2018 Dec 12;9:1857,yangbi@missouri.edu,"The triple mutant of the X. oryzae pv. oryzae strain PXO99A lacking XopZ, XopN and XopV showed additively reduced virulence.",J Long 2018,2018,3 genes,Long-2018-Non-TAL Effectors From Xanthomonas o,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13059,PHI:8738,UniProt,A0A0K0GQN3,GenBank,ACD61453,,,PXO99A,XopN,,,,,,PHI:8739,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30631333,PubMed,10.3389/fpls.2018.01857,Front Plant Sci. 2018 Dec 12;9:1857,yangbi@missouri.edu,"The triple mutant of the X. oryzae pv. oryzae strain PXO99A lacking XopZ, XopN and XopV showed additively reduced virulence.",J Long 2018,2018,3 genes,Long-2018-Non-TAL Effectors From Xanthomonas o,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13060,PHI:8739,UniProt,G7TBH8,,,,,PXO99A,XopV,,,,,,PHI:8738,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30631333,PubMed,10.3389/fpls.2018.01857,Front Plant Sci. 2018 Dec 12;9:1857,yangbi@missouri.edu,"The triple mutant of the X. oryzae pv. oryzae strain PXO99A lacking XopZ, XopN and XopV showed additively reduced virulence.",J Long 2018,2018,3 genes,Long-2018-Non-TAL Effectors From Xanthomonas o,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13061,PHI:8738,UniProt,A0A0K0GQN3,GenBank,ACD61453,,,PXO99A,XopN,,,,,,PHI:8739; PHI:8740,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30631333,PubMed,10.3389/fpls.2018.01857,Front Plant Sci. 2018 Dec 12;9:1857,yangbi@missouri.edu,"The triple mutant of the X. oryzae pv. oryzae strain PXO99A lacking XopZ, XopN and XopV showed additively reduced virulence.",J Long 2018,2018,3 genes,Long-2018-Non-TAL Effectors From Xanthomonas o,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13062,PHI:8739,UniProt,G7TBH8,,,,,PXO99A,XopV,,,,,,PHI:8738; PHI:8740,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30631333,PubMed,10.3389/fpls.2018.01857,Front Plant Sci. 2018 Dec 12;9:1857,yangbi@missouri.edu,"The triple mutant of the X. oryzae pv. oryzae strain PXO99A lacking XopZ, XopN and XopV showed additively reduced virulence.",J Long 2018,2018,3 genes,Long-2018-Non-TAL Effectors From Xanthomonas o,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13063,PHI:8740,UniProt,G7TFJ1,,,,,,XopZ,,,,,,PHI:8738; PHI:8739,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Kitaake,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30631333,PubMed,10.3389/fpls.2018.01857,Front Plant Sci. 2018 Dec 12;9:1857,yangbi@missouri.edu,"The triple mutant of the X. oryzae pv. oryzae strain PXO99A lacking XopZ, XopN and XopV showed additively reduced virulence.",J Long 2018,2018,3 genes,Long-2018-Non-TAL Effectors From Xanthomonas o,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13064,PHI:8741,UniProt,Q5ALW4,GenBank,XP_722512,,,SC5314,Pah1,chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphatidate phosphatase,,,,reduced virulence,,,,yes,,,,reduced; aberrant,,no,NaCl; Congo red; calcofluor white; caspofungin; sorbitol,NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30615943,PubMed,10.1016/j.fgb.2018.12.010,Fungal Genet Biol. 2019 Jan 4;124:47-58,jlsang@bnu.edu.cn,"Deleting PAH1 caused multiple phenotypes, especially severe hyphal defects, increased sensitivity to cell wall stress, and reduced virulence in mice.",C Mu 2019,2019,1 gene,Mu-2019-Phosphatidate phosphatase Pah1 has a r,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13065,PHI:8742,UniProt,Q87IK0,GenBank,BAC61949,,,RIMD 2210633,QsvR (VPA0606),chromosome 2,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative AraC-type regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30623553,PubMed,10.1111/1462-2920.14524,Environ Microbiol. 2019 Jan 8,dongshengzhou1977@gmail.com,"QsvR activated the mouse lethality, cytotoxicity, hemolytic activity, and enterotoxicity of V. parahaemolyticus.",Y Zhang 2019,2019,1 gene,Zhang-2019-QsvR integrates into quorum sensing,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13066,PHI:8742,UniProt,Q87IK0,GenBank,BAC61949,,,RIMD 2210633,QsvR (VPA0606),chromosome 2,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,putative AraC-type regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30623553,PubMed,10.1111/1462-2920.14524,Environ Microbiol. 2019 Jan 8,dongshengzhou1977@gmail.com,"QsvR activated the mouse lethality, cytotoxicity, hemolytic activity, and enterotoxicity of V. parahaemolyticus.",Y Zhang 2019,2019,1 gene,Zhang-2019-QsvR integrates into quorum sensing,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13067,PHI:8742,UniProt,Q87IK0,GenBank,BAC61949,,,RIMD 2210633,QsvR (VPA0606),chromosome 2,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,ileum,putative AraC-type regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30623553,PubMed,10.1111/1462-2920.14524,Environ Microbiol. 2019 Jan 8,dongshengzhou1977@gmail.com,"QsvR activated the mouse lethality, cytotoxicity, hemolytic activity, and enterotoxicity of V. parahaemolyticus.",Y Zhang 2019,2019,1 gene,Zhang-2019-QsvR integrates into quorum sensing,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13068,PHI:8743,UniProt,I1RRW0,GenBank,CEF85136,,,PH-1,FgPEX4 (FGSG_06857),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,inflorescence,uncharacterized protein,,,mycotoxin deoxynivalenol (DON) synthesis,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,H2O2; Congo red; SDS,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30603875,PubMed,10.1007/s00294-018-0925-6,Curr Genet. 2019 Jan 2,jfyu@sdau.edu.cn,"ΔPEX4 displayed reduced mycelial growth, conidiation, and the production of perithecia, ΔPEX4 was defective in pathogenicity and production of the mycotoxin deoxynivalenol (DON).",L Zhang 2019,2019,1 gene,Zhang-2019-FgPEX4 is involved in development,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13069,PHI:8743,UniProt,I1RRW0,GenBank,CEF85136,,,PH-1,FgPEX4 (FGSG_06857),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,uncharacterized protein,,,mycotoxin deoxynivalenol (DON) synthesis,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,H2O2; Congo red; SDS,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30603875,PubMed,10.1007/s00294-018-0925-6,Curr Genet. 2019 Jan 2,jfyu@sdau.edu.cn,"ΔPEX4 displayed reduced mycelial growth, conidiation, and the production of perithecia, ΔPEX4 was defective in pathogenicity and production of the mycotoxin deoxynivalenol (DON).",L Zhang 2019,2019,1 gene,Zhang-2019-FgPEX4 is involved in development,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13070,PHI:8743,UniProt,I1RRW0,GenBank,CEF85136,,,PH-1,FgPEX4 (FGSG_06857),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4530,Oryza sativa (related: rice),,,,caryopsis,uncharacterized protein,,,mycotoxin deoxynivalenol (DON) synthesis,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,H2O2; Congo red; SDS,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30603875,PubMed,10.1007/s00294-018-0925-6,Curr Genet. 2019 Jan 2,jfyu@sdau.edu.cn,"ΔPEX4 displayed reduced mycelial growth, conidiation, and the production of perithecia, ΔPEX4 was defective in pathogenicity and production of the mycotoxin deoxynivalenol (DON).",L Zhang 2019,2019,1 gene,Zhang-2019-FgPEX4 is involved in development,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13071,PHI:8744,UniProt,A0A1I7SAD6,GenBank,AYV64573,,,,Bx-cpl-1,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,88730,Pinus massoniana (related: chinese red pine),,,,seedling,cathepsin L-like cysteine proteinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30626082,PubMed,10.3390/ijms20010215,Int J Mol Sci. 2019 Jan 8;20(1). pii: E215,xqwu_njfu@163.com,"The silencing of Bx-cpl reduced the feeding, reproduction and pathogenicity of PWN.",Q Xue 2019,2019,3 genes,Xue-2019-Cathepsin L-like Cysteine Proteinase,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13072,PHI:8745,UniProt,A0A3G4YQT0,GenBank,AYV64574,,,,Bx-cpl-2,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,88730,Pinus massoniana (related: chinese red pine),,,,seedling,cathepsin L-like cysteine proteinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30626082,PubMed,10.3390/ijms20010215,Int J Mol Sci. 2019 Jan 8;20(1). pii: E215,xqwu_njfu@163.com,"The silencing of Bx-cpl reduced the feeding, reproduction and pathogenicity of PWN.",Q Xue 2019,2019,3 genes,Xue-2019-Cathepsin L-like Cysteine Proteinase,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13073,PHI:8746,UniProt,A0A3G4YQS3,GenBank,AYV64575,,,,Bx-cpl-3,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,88730,Pinus massoniana (related: chinese red pine),,,,seedling,cathepsin L-like cysteine proteinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30626082,PubMed,10.3390/ijms20010215,Int J Mol Sci. 2019 Jan 8;20(1). pii: E215,xqwu_njfu@163.com,"The silencing of Bx-cpl reduced the feeding, reproduction and pathogenicity of PWN.",Q Xue 2019,2019,3 genes,Xue-2019-Cathepsin L-like Cysteine Proteinase,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13074,PHI:8747,UniProt,Q0P9C8,GenBank,CAL35243,,,NCTC 11168,pglB,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,gastroenteritis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,oligosaccharyltransferase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,30617158,PubMed,10.1074/mcp.RA118.001199,Mol Cell Proteomics. 2019 Jan 7. pii: mcp.RA118.001199,cordwell@sydney.edu.au,Significant reduction in human epithelial Caco-2 cell adherence and invasion was observed in ΔpglB C. jejuni NCTC11168 strain.,J A Cain 2019,2019,1 gene,Cain-2019-Proteomics reveals multiple phenotyp,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13075,PHI:8748,UniProt,A7ED62,GenBank,EDO00778,,,1980,Ssams2 (SS1G_03252),,,,,,,5180,Sclerotinia sclerotiorum,,UF1,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,GATA transcription factor,,,,reduced virulence,,yes,yes,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30574138,PubMed,10.3389/fmicb.2018.03031,Front Microbiol. 2018 Dec 6;9:3031,panhongyu@jlu.edu.cn,"Ssams2-silenced strains exhibited defect in hyphal growth, hyphal branching patterns, compound appressoria differentiation and the oxalic acid production compared to the wild-type (WT) strain.",L Liu 2018,2018,1 gene,"Liu-2018-Ssams2, a Gene Encoding GATA Transcri",BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13076,PHI:8749,UniProt,Q5AD07,GenBank,AOW27120,,,SC5314,sod5,chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10117,Rattus rattus (related: black rat),,,,,cell surface Cu-only superoxide dismutase 5,,,,reduced virulence,,,,,,,,wild type,,no,"ammonium tetrathiomolybdate; diethyldithiocarbamate; clioquinol; deferoxamine; pyrithione zinc; ciclopirox; chloroxine; 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt (WST-1)","ammonium tetrathiomolybdate CAS no.: CAS:15060-55-6; diethyldithiocarbamate CAS no.: CAS:392-74-5; clioquinol CAS no.: CAS:130-26-7; deferoxamine CAS no.: CAS:70-51-9; pyrithione zinc: CHEBI:32076; ciclopirox: CHEBI:453011; chloroxine: CHEBI:59477; 2- (4-iodophenyl) -3- (4-nitrophenyl) -5- (2,4-disulfophenyl) -2H-tetrazolium,  monosodium salt (WST-1) CAS no.: CAS:150849-52-8",,,,,gene mutation,,,YVS,30593499,PubMed,10.1074/jbc.RA118.007095,J Biol Chem. 2018 Dec 28. pii: jbc.RA118.007095,vculott1@jhu.edu,Deletion of SOD5 eradicated candidal biofilms on venous catheters in a rodent model and sod5Δ/Δ strains in biofilms were also hypersensitive to killing by neutrophils.,R G Robinett 2018,2018,1 gene,Robinett-2018-Exploiting the vulnerable active,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13077,PHI:8749,UniProt,Q5AD07,GenBank,AOW27120,,,SC5314,sod5,chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,cell surface Cu-only superoxide dismutase 5,,,,reduced virulence,,,,,,,,wild type,,no,"ammonium tetrathiomolybdate; diethyldithiocarbamate; clioquinol; deferoxamine; pyrithione zinc; ciclopirox; chloroxine; 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt (WST-1)","ammonium tetrathiomolybdate CAS no.: CAS:15060-55-6; diethyldithiocarbamate CAS no.: CAS:392-74-5; clioquinol CAS no.: CAS:130-26-7; deferoxamine CAS no.: CAS:70-51-9; pyrithione zinc: CHEBI:32076; ciclopirox: CHEBI:453011; chloroxine: CHEBI:59477; 2- (4-iodophenyl) -3- (4-nitrophenyl) -5- (2,4-disulfophenyl) -2H-tetrazolium,  monosodium salt (WST-1) CAS no.: CAS:150849-52-8",,,,,gene mutation,,,YVS,30593499,PubMed,10.1074/jbc.RA118.007095,,vculott1@jhu.edu,Deletion of SOD5 eradicated candidal biofilms on venous catheters in a rodent model and sod5Δ/Δ strains in biofilms were also hypersensitive to killing by neutrophils.,R G Robinett 2018,2018,1 gene,Robinett-2018-Exploiting the vulnerable active,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13078,PHI:8750,UniProt,A0A0K0GHI2,GenBank,ACD57640,,,PXO99A,triP (PXO_04421),,,,pdeR,UniProt: no data found; GenBank: no data found,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,two-component system regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30589364,PubMed,10.1094/MPMI-09-18-0260-R,Mol Plant Microbe Interact. 2018 Dec 27,hechenyang@caas.cn,"The ΔtriP mutant showed significantly reduced virulence on susceptible rice leaves and impaired EPS production compared to wildtype, whereas the double mutant ΔtriPΔpdeR, likeΔpdeR, caused shorter lesion lengths and produced less EPS than ΔtriP.",H Li 2018,2018,2 genes,Li-2018-Xanthomonas oryzae pv. oryzae response,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13079,PHI:8751,,no data found,,,,,,pdeR,,,,triP (PXO_04421),UniProt: A0A0K0GHI2; GenBank: ACD57640,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,cyclic-di-GMP phosphodiesterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30589364,PubMed,10.1094/MPMI-09-18-0260-R,Mol Plant Microbe Interact. 2018 Dec 27,hechenyang@caas.cn,"The ΔtriP mutant showed significantly reduced virulence on susceptible rice leaves and impaired EPS production compared to wildtype, whereas the double mutant ΔtriPΔpdeR, likeΔpdeR, caused shorter lesion lengths and produced less EPS than ΔtriP.",H Li 2018,2018,2 genes,Li-2018-Xanthomonas oryzae pv. oryzae response,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13080,PHI:8750,UniProt,A0A0K0GHI2,GenBank,ACD57640,,,PXO99A,triP (PXO_04421),,,,pdeR,UniProt: no data found; GenBank: no data found,PHI:8751,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,two-component system regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30589364,PubMed,10.1094/MPMI-09-18-0260-R,Mol Plant Microbe Interact. 2018 Dec 27,hechenyang@caas.cn,"The ΔtriP mutant showed significantly reduced virulence on susceptible rice leaves and impaired EPS production compared to wildtype, whereas the double mutant ΔtriPΔpdeR, likeΔpdeR, caused shorter lesion lengths and produced less EPS than ΔtriP.",H Li 2018,2018,2 genes,Li-2018-Xanthomonas oryzae pv. oryzae response,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13081,PHI:8751,,no data found,,,,,,pdeR,,,,triP (PXO_04421),UniProt: A0A0K0GHI2; GenBank: ACD57640,PHI:8750,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,cyclic-di-GMP phosphodiesterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30589364,PubMed,10.1094/MPMI-09-18-0260-R,Mol Plant Microbe Interact. 2018 Dec 27,hechenyang@caas.cn,"The ΔtriP mutant showed significantly reduced virulence on susceptible rice leaves and impaired EPS production compared to wildtype, whereas the double mutant ΔtriPΔpdeR, likeΔpdeR, caused shorter lesion lengths and produced less EPS than ΔtriP.",H Li 2018,2018,2 genes,Li-2018-Xanthomonas oryzae pv. oryzae response,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13082,PHI:8752,UniProt,G4MRX0,GenBank,EHA56639,,,70-15,RHO2 (MGG_02457),chromosome 1,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,Rho GTPase,,,,reduced virulence,,yes,yes,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30588220,PubMed,10.5423/PPJ.OA.04.2018.0069,Plant Pathol J. 2018 Dec;34(6):470-479,kims@kangwon.ac.kr,"ΔMorho2 mutant was defective in plant penetration, but was still able to cause lesions, albeit at a reduced rate on wounded plants.",T Fu 2018,2018,1 gene,Fu-2018-A Small GTPase RHO2 Plays an Important,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13083,PHI:8753,UniProt,G4MXR2,GenBank,EHA55199,,,70-15,MoChia1 (MGG_08054),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf; leaf sheath,chitinase,,,MAPK pathway,reduced virulence,,yes,yes,,,reduced,,increased,reduced,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30610168,PubMed,10.1105/tpc.18.00382,Plant Cell. 2019 Jan 4. pii: tpc.00382.2018,Junliu@im.ac.cn,Knocking out MoChia1 significantly reduced the virulence of the fungus and MoChia1 binds chitin to suppress the chitin-triggered plant immune response.,C Yang 2019,2019,1 gene,Yang-2019-Binding of the Magnaporthe oryzae ch,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13084,PHI:8753,UniProt,G4MXR2,GenBank,EHA55199,,,70-15,MoChia1 (MGG_08054),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf; leaf sheath,chitinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,Congo red,Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30610168,PubMed,10.1105/tpc.18.00382,Plant Cell. 2019 Jan 4. pii: tpc.00382.2018,Junliu@im.ac.cn,Knocking out MoChia1 significantly reduced the virulence of the fungus and MoChia1 binds chitin to suppress the chitin-triggered plant immune response.,C Yang 2019,2019,1 gene,Yang-2019-Binding of the Magnaporthe oryzae ch,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13085,PHI:8753,UniProt,G4MXR2,GenBank,EHA55199,,,70-15,MoChia1 (MGG_08054),chromosome 2,MoChia1 E137Q overexpression,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf; leaf sheath,chitinase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,Congo red,Congo red: CHEBI:34653,,,,,gene mutation; altered gene expression / gene regulation: overexpression,,,YVS,30610168,PubMed,10.1105/tpc.18.00382,Plant Cell. 2019 Jan 4. pii: tpc.00382.2018,Junliu@im.ac.cn,Knocking out MoChia1 significantly reduced the virulence of the fungus and MoChia1 binds chitin to suppress the chitin-triggered plant immune response.,C Yang 2019,2019,1 gene,Yang-2019-Binding of the Magnaporthe oryzae ch,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13086,PHI:8754,UniProt,G4MSF9,GenBank,EHA53771,,,70-15,MoPer1 (MGG_04527),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,post-GPI attachment to proteins factor 3,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,,no,NaCl; KCl; SDS; Congo red; calcofluor white (CFW); difenoconazole (DCZ),NaCl: CHEBI:26710; KCl: CHEBI:32588; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; difenoconazole (DCZ): CHEBI:81760,,,,,gene deletion: full; gene complementation,,,YVS,30578458,PubMed,10.1186/s12284-018-0255-9,Rice (N Y). 2018 Dec 22;11(1):64,haoasliu@163.com,"MoPer1 was necessary for growth, conidiogenesis and pathogenicity of the fungus.",Y Chen 2018,2018,1 gene,"Chen-2018-MoPer1 is required for growth, conid",BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13087,PHI:8754,UniProt,G4MSF9,GenBank,EHA53771,,,70-15,MoPer1 (MGG_04527),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,post-GPI attachment to proteins factor 3,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,,no,NaCl; KCl; SDS; Congo red; calcofluor white (CFW); difenoconazole (DCZ),NaCl: CHEBI:26710; KCl: CHEBI:32588; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; difenoconazole (DCZ): CHEBI:81760,,,,,gene deletion: full; gene complementation,,,YVS,30578458,PubMed,10.1186/s12284-018-0255-9,Rice (N Y). 2018 Dec 22;11(1):64,haoasliu@163.com,"MoPer1 was necessary for growth, conidiogenesis and pathogenicity of the fungus.",Y Chen 2018,2018,1 gene,"Chen-2018-MoPer1 is required for growth, conid",BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13088,PHI:8755,UniProt,A0A0U1G333,GenBank,CNR65460,,,CH43,aroA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,3-phosphoshikimate 1-carboxyvinyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30574134,PubMed,10.3389/fmicb.2018.03001,Front Microbiol. 2018 Dec 6;9:3001,csantiviago@ciq.uchile.cl,Tat system was crucial for S. Typhimurium to survive and proliferate intracellularly in D. discoideum and for virulence in this host.,I M Urrutia 2018,2018,5 genes,Urrutia-2018-Contribution of the Twin-Arginine,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13089,PHI:8756,UniProt,P26976,GenBank,AAL23143,,,LT2,phoN,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,non-specific acid phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30574134,PubMed,10.3389/fmicb.2018.03001,Front Microbiol. 2018 Dec 6;9:3001,csantiviago@ciq.uchile.cl,Tat system was crucial for S. Typhimurium to survive and proliferate intracellularly in D. discoideum and for virulence in this host.,I M Urrutia 2018,2018,5 genes,Urrutia-2018-Contribution of the Twin-Arginine,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13090,PHI:8757,UniProt,A0A0U1FZZ2,GenBank,CNR43436,,,CH43,tatA,,,,,,PHI:8758; PHI:8759,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30574134,PubMed,10.3389/fmicb.2018.03001,Front Microbiol. 2018 Dec 6;9:3001,csantiviago@ciq.uchile.cl,Tat system was crucial for S. Typhimurium to survive and proliferate intracellularly in D. discoideum and for virulence in this host.,I M Urrutia 2018,2018,5 genes,Urrutia-2018-Contribution of the Twin-Arginine,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13091,PHI:8758,UniProt,A0A0U1FMH1,GenBank,CNR43407,,,CH43,tatB,,,,,,PHI:8757; PHI:8759,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30574134,PubMed,10.3389/fmicb.2018.03001,Front Microbiol. 2018 Dec 6;9:3001,csantiviago@ciq.uchile.cl,Tat system was crucial for S. Typhimurium to survive and proliferate intracellularly in D. discoideum and for virulence in this host.,I M Urrutia 2018,2018,5 genes,Urrutia-2018-Contribution of the Twin-Arginine,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13092,PHI:8759,UniProt,A0A0U1JBY1,GenBank,CNR43379,,,CH43,tatC,,,,,,PHI:8757; PHI:8758,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30574134,PubMed,10.3389/fmicb.2018.03001,Front Microbiol. 2018 Dec 6;9:3001,csantiviago@ciq.uchile.cl,Tat system was crucial for S. Typhimurium to survive and proliferate intracellularly in D. discoideum and for virulence in this host.,I M Urrutia 2018,2018,5 genes,Urrutia-2018-Contribution of the Twin-Arginine,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13093,PHI:8760,UniProt,B8NAR1,GenBank,EED52584,,,NRRL3357,RtfA (XP_002377748.1),,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),cv. NC94022,,,seed,RNA polymerase II transcription elongation factor,,,biosynthesis of secondary metabolites,reduced virulence,,,,,,reduced,,reduced,,no,SDS; menadione,SDS: CHEBI:8984; menadione: CHEBI:28869,,,,,gene mutation; gene complementation,,,YVS,30635379,PubMed,10.1128/AEM.02446-18,Appl Environ Microbiol. 2019 Jan 11. pii: AEM.02446-18,amcalvo@niu.edu,"RtfA positively regulated fungal invasion and colonization of host tissue, adhesion to surfaces, protease and lipase activity, cell wall composition and integrity, and tolerance to oxidative stress.",J M Lohmar 2019,2019,1 gene,Lohmar-2019-The rtfA gene regulates plant and,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13094,PHI:8760,UniProt,B8NAR1,GenBank,EED52584,,,NRRL3357,RtfA (XP_002377748.1),,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RNA polymerase II transcription elongation factor,,,biosynthesis of secondary metabolites,reduced virulence,,,,,,,,reduced,,no,SDS; menadione,SDS: CHEBI:8984; menadione: CHEBI:28869,,,,,gene mutation; gene complementation,,,YVS,30635379,PubMed,10.1128/AEM.02446-18,Appl Environ Microbiol. 2019 Jan 11. pii: AEM.02446-18,amcalvo@niu.edu,"RtfA positively regulated fungal invasion and colonization of host tissue, adhesion to surfaces, protease and lipase activity, cell wall composition and integrity, and tolerance to oxidative stress.",J M Lohmar 2019,2019,1 gene,Lohmar-2019-The rtfA gene regulates plant and,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13095,PHI:8761,,no data found,,,,,,FolCzf1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,root,C2H2 transcription factor,,,fusaric acid biosynthesis,loss of pathogenicity,,no,no,yes,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30631890,PubMed,10.1007/s00294-019-00931-9,Curr Genet. 2019 Jan 10,wangzh@fafu.edu.cn,"FolCzf1 was required for conidiation, secondary metabolism and early host infection in Fol.",Y Yun 2019,2019,1 gene,Yun-2019-Fusarium oxysporum f. sp. Lycopersici,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13096,PHI:8761,,no data found,,,,,,FolCzf1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,C2H2 transcription factor,,,fusaric acid biosynthesis,reduced virulence,,,,,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30631890,PubMed,10.1007/s00294-019-00931-9,Curr Genet. 2019 Jan 10,wangzh@fafu.edu.cn,"FolCzf1 was required for conidiation, secondary metabolism and early host infection in Fol.",Y Yun 2019,2019,1 gene,Yun-2019-Fusarium oxysporum f. sp. lycopersici,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13097,PHI:8761,,no data found,,,,,,FolCzf1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,3750,Malus domestica (related: apple),cv. Ailsa Craig,,,fruit,C2H2 transcription factor,,,fusaric acid biosynthesis,reduced virulence,,,,,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30631890,PubMed,10.1007/s00294-019-00931-9,Curr Genet. 2019 Jan 10,wangzh@fafu.edu.cn,"FolCzf1 was required for conidiation, secondary metabolism and early host infection in Fol.",Y Yun 2019,2019,1 gene,Yun-2019-Fusarium oxysporum f. sp. lycopersici,BATCH_089A,2019-01-01,MC,,,,,,,,,,,,,
,,Record 13098,PHI:8762,UniProt,A0A0D1E0C2,GenBank,KIS68180,,,521,ptn1 (UMAG_03760),chromosome 10,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling,hypothetical protein,,,PTEN/PI3K/mTOR signal transduction pathway,reduced virulence,yes,,,,,reduced,,wild type,reduced,no,sorbitol; NaCl; Congo red (CR); calcofluor white (CFW),sorbitol: CHEBI:30911; NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,30577430,PubMed,10.3390/jof5010001,J Fungi (Basel). 2018 Dec 20;5(1). pii: E1,michael.groeschen@louisville.edu,"While the overexpression of ptn1 had no substantial effects on virulence, ptn1 deletion strains showed slight reductions in mating effciency and significant reductions in virulence; tumor formation on stem and/or leaves were severely reduced.",L M K Vijayakrishnapillai 2018,2018,1 gene,"Vijayakrishnapi-2018-Deletion of ptn1, a PTEN_",BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13099,PHI:8762,UniProt,A0A0D1E0C2,GenBank,KIS68180,,,521,ptn1 (UMAG_03760),chromosome 10,ptn1 otef overexpression strain,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Golden Bantam,,,seedling,hypothetical protein,,,PTEN/PI3K/mTOR signal transduction pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,sorbitol; NaCl; Congo red (CR); calcofluor white (CFW),sorbitol: CHEBI:30911; NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30577430,PubMed,10.3390/jof5010001,J Fungi (Basel). 2018 Dec 20;5(1). pii: E1,michael.groeschen@louisville.edu,"While the overexpression of ptn1 had no substantial effects on virulence, ptn1 deletion strains showed slight reductions in mating effciency and significant reductions in virulence; tumor formation on stem and/or leaves were severely reduced.",L M K Vijayakrishnapillai 2018,2018,1 gene,"Vijayakrishnapi-2018-Deletion of ptn1, a PTEN_",BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13100,PHI:8763,UniProt,P9WJB9,GenBank,CCP46709,,,H37Rv,espL,,,,espD,UniProt: P9WJD5; GenBank: CCP46437,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,ESX-1 secretion-associated protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30571761,PubMed,10.1371/journal.ppat.1007491,PLoS Pathog. 2018 Dec 20;14(12):e1007491,stewart.cole@epfl.ch,Infection of THP-1 cells demonstrated severe reduction of the cytotoxicity of the espL mutant.,C Sala 2018,2018,1 gene,Sala-2018-EspL is essential for virulence and,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13101,PHI:8764,UniProt,G3XCU6,GenBank,AE004601_8,,,PAO1,cysB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,LysR-type transcriptional regulator,,,cysteine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30618115,PubMed,10.1111/mmi.14200,Mol Microbiol. 2019 Jan 7,lianghh@nwu.edu.cn,Deletion of cysB reduced T3SS gene expression and swarming motility but enhanced biofilm formation.,Y Song 2019,2019,2 genes,Song-2019-Molecular insights into the master r,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13102,PHI:8765,UniProt,P26993,GenBank,AE004598_1,,,PAO1,exsa,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,exoenzyme S synthesis regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30618115,PubMed,10.1111/mmi.14200,Mol Microbiol. 2019 Jan 7,lianghh@nwu.edu.cn,The pathogenesis of ΔcysB mutant was more severe than ΔexsA mutant.,Y Song 2019,2019,2 genes,Song-2019-Molecular insights into the master r,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13103,PHI:8766,,no data found,,,,,,bdr1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,amphotericin B,amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,30602579,PubMed,10.1128/mBio.01726-18,MBio. 2019 Jan 2;10(1). pii: e01726-18,ysbahn@yonsei.ac.kr,"Perturbation of both RAD53 and CHK1 attenuated the virulence of C. neoformans, perhaps by promoting phagosome maturation within macrophage, reducing melanin production, and increasing susceptibility to oxidative stresses.",K W Jung 2019,2019,3 genes,Jung-2019-Rad53- and Chk1-Dependent DNA Damage,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13104,PHI:8767,UniProt,A0A226BL10,GenBank,OWZ78984,,,Bt85,rad53,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,protein kinase,,,,unaffected pathogenicity,,,,,,,,,,no,amphotericin B,amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,30602579,PubMed,10.1128/mBio.01726-18,MBio. 2019 Jan 2;10(1). pii: e01726-18,ysbahn@yonsei.ac.kr,"Perturbation of both RAD53 and CHK1 attenuated the virulence of C. neoformans, perhaps by promoting phagosome maturation within macrophage, reducing melanin production, and increasing susceptibility to oxidative stresses.",K W Jung 2019,2019,3 genes,Jung-2019-Rad53- and Chk1-Dependent DNA Damage,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13105,PHI:8768,UniProt,A0A226B923,GenBank,OWZ75473,,,Bt85,chk1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,effector kinase,,,,unaffected pathogenicity,,,,,,,,,,no,amphotericin B,amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,30602579,PubMed,10.1128/mBio.01726-18,MBio. 2019 Jan 2;10(1). pii: e01726-18,ysbahn@yonsei.ac.kr,"Perturbation of both RAD53 and CHK1 attenuated the virulence of C. neoformans, perhaps by promoting phagosome maturation within macrophage, reducing melanin production, and increasing susceptibility to oxidative stresses.",K W Jung 2019,2019,3 genes,Jung-2019-Rad53- and Chk1-Dependent DNA Damage,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13106,PHI:8767,UniProt,A0A226BL10,GenBank,OWZ78984,,,Bt85,rad53,,,,,,PHI:8768,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,protein kinase,,,,reduced virulence,,,,,,,,,,no,amphotericin B,amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,30602579,PubMed,10.1128/mBio.01726-18,MBio. 2019 Jan 2;10(1). pii: e01726-18,ysbahn@yonsei.ac.kr,"Perturbation of both RAD53 and CHK1 attenuated the virulence of C. neoformans, perhaps by promoting phagosome maturation within macrophage, reducing melanin production, and increasing susceptibility to oxidative stresses.",K W Jung 2019,2019,3 genes,Jung-2019-Rad53- and Chk1-Dependent DNA Damage,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13107,PHI:8768,UniProt,A0A226B923,GenBank,OWZ75473,,,Bt85,chk1,,,,,,PHI:8767,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,,effector kinase,,,,reduced virulence,,,,,,,,,,no,amphotericin B,amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,30602579,PubMed,10.1128/mBio.01726-18,MBio. 2019 Jan 2;10(1). pii: e01726-18,ysbahn@yonsei.ac.kr,"Perturbation of both RAD53 and CHK1 attenuated the virulence of C. neoformans, perhaps by promoting phagosome maturation within macrophage, reducing melanin production, and increasing susceptibility to oxidative stresses.",K W Jung 2019,2019,3 genes,Jung-2019-Rad53- and Chk1-Dependent DNA Damage,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13108,PHI:8769,UniProt,E9DS54,GenBank,XP_007806792,,,CQMa 102,MaPpt1,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,,ser/Thr protein phosphatase,,,,unaffected pathogenicity,,,,,,increased; aberrant,,,increased,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30610282,PubMed,10.1007/s00253-018-9567-3,Appl Microbiol Biotechnol. 2019 Jan 4,yuxianxia@cqu.edu.cn,ΔMaPpt1 displayed increased UV tolerance compared to wild type.,J Zhang 2019,2019,1 gene,Zhang-2019-The protein phosphatase gene MaPpt1,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13109,PHI:8770,UniProt,N1PC72,GenBank,EME39782,,,NZE10,cfpks1,,,,,,,5499,Fulvia fulva,,,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,non-reducing polyketide synthase,,,DHN melanin biosynthesis,unaffected pathogenicity,,,,,,,,,,no,hydroquinone; pyroquilon,hydroquinone: CHEBI:17594; pyroquilon: CHEBI:45141,,,,,gene deletion: full; gene complementation,,,YVS,30596695,PubMed,10.1371/journal.pone.0209600,PLoS One. 2018 Dec 31;13(12):e0209600,j.collemare@westerdijkinstitute.nl,"CfPKS1 was needed for proper pigmentation of C. fulvum, but was not required for pathogenicity on tomato.",S A Griffiths 2018,2018,1 gene,Griffiths-2018-Assignment of a dubious gene cl,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13110,PHI:8771,UniProt,E3KHU8,GenBank,EFP83873,,,CRL 75-36-700-3,PgtSR1 (PGTG_09586),,,,,,,5297,Puccinia graminis,,f. sp. tritici,stem rust,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30623449,PubMed,10.1111/nph.15676,New Phytol. 2019 Jan 9,scot_hulbert@wsu.edu,PgtSR1 effector protein suppressed RNA silencing in plants and impeded plant defenses by altering the abundance of small RNAs that serve as defense regulators.,C Yin 2019,2019,1 gene,Yin-2019-A novel fungal effector from Puccinia,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13111,PHI:8771,UniProt,E3KHU8,GenBank,EFP83873,,,CRL 75-36-700-3,PgtSR1 (PGTG_09586),,,,,,,5297,Puccinia graminis,,f. sp. tritici,stem rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. McNair 701,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30623449,PubMed,10.1111/nph.15676,New Phytol. 2019 Jan 9,scot_hulbert@wsu.edu,PgtSR1 effector protein suppressed RNA silencing in plants and impeded plant defenses by altering the abundance of small RNAs that serve as defense regulators.,C Yin 2019,2019,1 gene,Yin-2019-A novel fungal effector from Puccinia,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13112,PHI:8771,UniProt,E3KHU8,GenBank,EFP83873,,,CRL 75-36-700-3,PgtSR1 (PGTG_09586),,,,,,,5297,Puccinia graminis,,f. sp. tritici,stem rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Thatcher-Sr31,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30623449,PubMed,10.1111/nph.15676,New Phytol. 2019 Jan 9,scot_hulbert@wsu.edu,PgtSR1 effector protein suppressed RNA silencing in plants and impeded plant defenses by altering the abundance of small RNAs that serve as defense regulators.,C Yin 2019,2019,1 gene,Yin-2019-A novel fungal effector from Puccinia,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13113,PHI:8771,UniProt,E3KHU8,GenBank,EFP83873,,,CRL 75-36-700-3,PgtSR1 (PGTG_09586),,,,,,,5297,Puccinia graminis,,f. sp. tritici,stem rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30623449,PubMed,10.1111/nph.15676,New Phytol. 2019 Jan 9,scot_hulbert@wsu.edu,PgtSR1 effector protein suppressed RNA silencing in plants and impeded plant defenses by altering the abundance of small RNAs that serve as defense regulators.,C Yin 2019,2019,1 gene,Yin-2019-A novel fungal effector from Puccinia,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13114,PHI:8772,UniProt,Q8PRL3,GenBank,AAM39253,,,306,mltB2.1 (XAC_RS22275),,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera Rio,,,leaf,lytic murein transglycosylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30588403,PubMed,10.7717/peerj.6111,PeerJ. 2018 Dec 19;6:e6111,alessandro.varani@unesp.br,MltB2.1 and mltB2.2 had only a moderate impact on biofilm formation and xanthan gum production but none on cell aggregation and motility.,A C P Oliveira 2018,2018,2 genes,Oliveira-2018-Transposons and pathogenicity in,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13115,PHI:8773,UniProt,Q8PHM6,GenBank,AAM38069,,,306,mltB2.2 (XAC_RS16355),,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Pera Rio,,,leaf,lytic murein transglycosylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30588403,PubMed,10.7717/peerj.6111,PeerJ. 2018 Dec 19;6:e6111,alessandro.varani@unesp.br,MltB2.1 and mltB2.2 had only a moderate impact on biofilm formation and xanthan gum production but none on cell aggregation and motility.,A C P Oliveira 2018,2018,2 genes,Oliveira-2018-Transposons and pathogenicity in,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13116,PHI:8774,UniProt,B0FLN1,GenBank,ABY50954,,,M2,abaI,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,acyl-homoserine-lactone synthase,,,,reduced virulence,,,,,,,,,,no,N-(3-oxo-dodecanoyl)-L-homoserine lactone (3-OH-C12-HSL); H2O2,N-(3-oxo-dodecanoyl)-L-homoserine lactone (3-OH-C12-HSL): CHEBI:44534; H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,30619184,PubMed,10.3389/fmicb.2018.03105,Front Microbiol. 2018 Dec 17;9:3105,ma.del.mar.tomas.carmona@sergas.es,"In an in vivo Galleria mellonella model of A. baumannii infection, the A. baumannii ATCC17978 strain was associated with higher mortality (100% at 24h) than the abaI-deficient strain (70% at 24h).",L Fernandez-Garcia 2018,2018,1 gene,Fernandez-Garci-2018-Relationship Between the,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13117,PHI:8775,,no data found,GenBank,CAH13479,,,Paris,lvbR (Lpp2326),,,,,,,446,Legionella pneumophila,272624,JR32,Legionnaires' disease; pneumonia,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX3,,,,pleotropic transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30623561,PubMed,10.1111/1462-2920.14523,Environ Microbiol. 2019 Jan 8,hilbi@imm.uzh.ch,LvbR played a role in regulating the uptake of L. pneumophila as well as the inhibition of host cell migration and chemotaxis by the pathogen.,R Hochstrasser 2019,2019,1 gene,Hochstrasser-2019-The pleotropic Legionella tr,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13118,PHI:8775,,no data found,GenBank,CAH13479,,,Paris,lvbR (Lpp2326),,,,,,,446,Legionella pneumophila,272624,JR32,Legionnaires' disease; pneumonia,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,pleotropic transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30623561,PubMed,10.1111/1462-2920.14523,Environ Microbiol. 2019 Jan 8,hilbi@imm.uzh.ch,LvbR played a role in regulating the uptake of L. pneumophila as well as the inhibition of host cell migration and chemotaxis by the pathogen.,R Hochstrasser 2019,2019,1 gene,Hochstrasser-2019-The pleotropic Legionella tr,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13119,PHI:8775,,no data found,GenBank,CAH13479,,,Paris,lvbR (Lpp2326),,,,,,,446,Legionella pneumophila,272624,JR32,Legionnaires' disease; pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,pleotropic transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30623561,PubMed,10.1111/1462-2920.14523,Environ Microbiol. 2019 Jan 8,hilbi@imm.uzh.ch,LvbR played a role in regulating the uptake of L. pneumophila as well as the inhibition of host cell migration and chemotaxis by the pathogen.,R Hochstrasser 2019,2019,1 gene,Hochstrasser-2019-The pleotropic Legionella tr,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13120,PHI:8776,UniProt,A0A069B091,GenBank,KGD52748,,,BES,ppk1,,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,polyphosphate kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30597312,PubMed,10.1016/j.jprot.2018.12.024,J Proteomics. 2019 Mar 1;194:14-24,patompon.won@mahidol.ac.th,Ppk1 defective strain showed a decrease in adhesion and invasion abilities to human lung epithelial cells A549.,K Srisanga 2018,2018,1 gene,Srisanga-2018-Polyphosphate kinase 1 of Burkho,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13121,PHI:8777,UniProt,A0A3N9JER8,GenBank,RQV53682,,,Bp8970,tssA,,,,,,,95486,Burkholderia cenocepacia,985075,H111,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30628184,PubMed,10.1002/mbo3.774,Microbiologyopen. 2019 Jan 9:e774,m.s.thomas@sheffield.ac.uk,Burkholderia cenocepacia T6SS-1 was not required for virulence in eukaryotic models of infection.,H L Spiewak 2019,2019,2 genes,Spiewak-2019-Burkholderia cenocepacia utilizes,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13122,PHI:8778,UniProt,B4E6S3,GenBank,CAR50661,,,J2315,tssM,chromosome 1,,,,,,95486,Burkholderia cenocepacia,985075,H111,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30628184,PubMed,10.1002/mbo3.774,Microbiologyopen. 2019 Jan 9:e774,m.s.thomas@sheffield.ac.uk,Burkholderia cenocepacia T6SS-1 was not required for virulence in eukaryotic models of infection.,H L Spiewak 2019,2019,2 genes,Spiewak-2019-Burkholderia cenocepacia utilizes,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13123,PHI:8777,UniProt,A0A3N9JER8,GenBank,RQV53682,,,Bp8970,tssA,,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30628184,PubMed,10.1002/mbo3.774,Microbiologyopen. 2019 Jan 9:e774,m.s.thomas@sheffield.ac.uk,Burkholderia cenocepacia T6SS-1 was not required for virulence in eukaryotic models of infection.,H L Spiewak 2019,2019,2 genes,Spiewak-2019-Burkholderia cenocepacia utilizes,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13124,PHI:8778,UniProt,B4E6S3,GenBank,CAR50661,,,J2315,tssM,chromosome 1,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30628184,PubMed,10.1002/mbo3.774,Microbiologyopen. 2019 Jan 9:e774,m.s.thomas@sheffield.ac.uk,Burkholderia cenocepacia T6SS-1 was not required for virulence in eukaryotic models of infection.,H L Spiewak 2019,2019,2 genes,Spiewak-2019-Burkholderia cenocepacia utilizes,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13125,PHI:8777,UniProt,A0A3N9JER8,GenBank,RQV53682,,,Bp8970,tssA,,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30628184,PubMed,10.1002/mbo3.774,Microbiologyopen. 2019 Jan 9:e774,m.s.thomas@sheffield.ac.uk,Burkholderia cenocepacia T6SS-1 was not required for virulence in eukaryotic models of infection.,H L Spiewak 2019,2019,2 genes,Spiewak-2019-Burkholderia cenocepacia utilizes,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13126,PHI:8778,UniProt,B4E6S3,GenBank,CAR50661,,,J2315,tssM,chromosome 1,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30628184,PubMed,10.1002/mbo3.774,Microbiologyopen. 2019 Jan 9:e774,m.s.thomas@sheffield.ac.uk,Burkholderia cenocepacia T6SS-1 was not required for virulence in eukaryotic models of infection.,H L Spiewak 2019,2019,2 genes,Spiewak-2019-Burkholderia cenocepacia utilizes,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13127,PHI:8779,,no data found,,,,,,MoNIS1,,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30584105,PubMed,10.1073/pnas.1807297116,Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):496-505,ytakano@kais.kyoto-u.ac.jp,Host gene alteration data available for PRR-associated kinases BAK1 and BIK1 from A. thaliana. MoNIS1 expression significantly enhanced lesion development by C. orbiculare in N. benthamiana.,H Irieda 2019,2019,1 gene,Irieda-2019-Conserved fungal effector suppress,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13128,PHI:8779,,no data found,,,,,,MoNIS1,,,,,,,318829,Magnaporthe oryzae,,Guy11 Δku70,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Moukoto,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30584105,PubMed,10.1073/pnas.1807297116,Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):496-505,ytakano@kais.kyoto-u.ac.jp,Host gene alteration data available for PRR-associated kinases BAK1 and BIK1 from A. thaliana. Inoculation assays of MoNIS1 knockout the mutant on barley and rice revealed that it possessed severely reduced virulence.,H Irieda 2019,2019,1 gene,Irieda-2019-Conserved fungal effector suppress,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13129,PHI:8779,,no data found,,,,,,MoNIS1,,,,,,,318829,Magnaporthe oryzae,,Guy11 Δku70,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Nigrate,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30584105,PubMed,10.1073/pnas.1807297116,Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):496-505,ytakano@kais.kyoto-u.ac.jp,Host gene alteration data available for PRR-associated kinases BAK1 and BIK1 from A. thaliana. Inoculation assays of MoNIS1 knockout the mutant on barley and rice revealed that it possessed severely reduced virulence.,H Irieda 2019,2019,1 gene,Irieda-2019-Conserved fungal effector suppress,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13130,PHI:8780,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,PHI:8781,1280,Staphylococcus aureus,367830,USA300,pneumonia,primates,9606,Homo sapiens (related: human),,,,erythrocyte,two-component sensory system response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30619166,PubMed,10.3389/fmicb.2018.03085,Front Microbiol. 2018 Dec 14;9:3085,tyler.nygaard@msu.montana.edu,Aspartic Acid residue 51 of SaeR was essential for the SaeR/S mediated hemolysis of human erythrocytes by USA300.,T K Nygaard 2018,2018,2 genes,Nygaard-2018-Aspartic Acid Residue 51 of SaeR,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13131,PHI:8781,UniProt,Q2G2U1,GenBank,CAD89115,,,ISP479C,saeS,,,,,,PHI:8780,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,primates,9606,Homo sapiens (related: human),,,,erythrocyte,two-component sensory system histidine protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30619166,PubMed,10.3389/fmicb.2018.03085,Front Microbiol. 2018 Dec 14;9:3085,tyler.nygaard@msu.montana.edu,Aspartic Acid residue 51 of SaeR was essential for the SaeR/S mediated hemolysis of human erythrocytes by USA300.,T K Nygaard 2018,2018,2 genes,Nygaard-2018-Aspartic Acid Residue 51 of SaeR,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13132,PHI:8780,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,USA300ΔsaeR-D51A,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,primates,9606,Homo sapiens (related: human),,,,erythrocyte,two-component sensory system response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30619166,PubMed,10.3389/fmicb.2018.03085,Front Microbiol. 2018 Dec 14;9:3085,tyler.nygaard@msu.montana.edu,Aspartic Acid residue 51 of SaeR was essential for the SaeR/S mediated hemolysis of human erythrocytes by USA300.,T K Nygaard 2018,2018,2 genes,Nygaard-2018-Aspartic Acid Residue 51 of SaeR,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13133,PHI:8780,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,USA300ΔsaeR-D46A,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,primates,9606,Homo sapiens (related: human),,,,erythrocyte,two-component sensory system response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30619166,PubMed,10.3389/fmicb.2018.03085,Front Microbiol. 2018 Dec 14;9:3085,tyler.nygaard@msu.montana.edu,Aspartic Acid residue 51 of SaeR was essential for the SaeR/S mediated hemolysis of human erythrocytes by USA300.,T K Nygaard 2018,2018,2 genes,Nygaard-2018-Aspartic Acid Residue 51 of SaeR,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13134,PHI:8780,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,USA300ΔsaeR-D61A,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,primates,9606,Homo sapiens (related: human),,,,erythrocyte,two-component sensory system response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30619166,PubMed,10.3389/fmicb.2018.03085,Front Microbiol. 2018 Dec 14;9:3085,tyler.nygaard@msu.montana.edu,Aspartic Acid residue 51 of SaeR was essential for the SaeR/S mediated hemolysis of human erythrocytes by USA300.,T K Nygaard 2018,2018,2 genes,Nygaard-2018-Aspartic Acid Residue 51 of SaeR,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13135,PHI:8780,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,two-component sensory system response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30619166,PubMed,10.3389/fmicb.2018.03085,Front Microbiol. 2018 Dec 14;9:3085,tyler.nygaard@msu.montana.edu,USA300 pathogenesis during murine soft-tissue infection is dependent upon aspartic acid residue 51 of SaeR while aspartic acid residues 46 and 61 are not essential for causing disease.,T K Nygaard 2018,2018,2 genes,Nygaard-2018-Aspartic Acid Residue 51 of SaeR,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13136,PHI:8781,UniProt,Q2G2U1,GenBank,CAD89115,,,ISP479C,saeS,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,two-component sensory system response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30619166,PubMed,10.3389/fmicb.2018.03085,Front Microbiol. 2018 Dec 14;9:3085,tyler.nygaard@msu.montana.edu,USA300 pathogenesis during murine soft-tissue infection is dependent upon aspartic acid residue 51 of SaeR while aspartic acid residues 46 and 61 are not essential for causing disease.,T K Nygaard 2018,2018,2 genes,Nygaard-2018-Aspartic Acid Residue 51 of SaeR,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13137,PHI:8780,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,USA300ΔsaeR-D51A,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,two-component sensory system response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30619166,PubMed,10.3389/fmicb.2018.03085,Front Microbiol. 2018 Dec 14;9:3085,tyler.nygaard@msu.montana.edu,USA300 pathogenesis during murine soft-tissue infection is dependent upon aspartic acid residue 51 of SaeR while aspartic acid residues 46 and 61 are not essential for causing disease.,T K Nygaard 2018,2018,2 genes,Nygaard-2018-Aspartic Acid Residue 51 of SaeR,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13138,PHI:8780,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,USA300ΔsaeR-D46A,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,two-component sensory system response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30619166,PubMed,10.3389/fmicb.2018.03085,Front Microbiol. 2018 Dec 14;9:3085,tyler.nygaard@msu.montana.edu,USA300 pathogenesis during murine soft-tissue infection is dependent upon aspartic acid residue 51 of SaeR while aspartic acid residues 46 and 61 are not essential for causing disease.,T K Nygaard 2018,2018,2 genes,Nygaard-2018-Aspartic Acid Residue 51 of SaeR,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13139,PHI:8780,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,USA300ΔsaeR-D61A,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,two-component sensory system response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30619166,PubMed,10.3389/fmicb.2018.03085,Front Microbiol. 2018 Dec 14;9:3085,tyler.nygaard@msu.montana.edu,USA300 pathogenesis during murine soft-tissue infection is dependent upon aspartic acid residue 51 of SaeR while aspartic acid residues 46 and 61 are not essential for causing disease.,T K Nygaard 2018,2018,2 genes,Nygaard-2018-Aspartic Acid Residue 51 of SaeR,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13140,PHI:8782,UniProt,A0A346QRX8,GenBank,AXR99089,,,,MaMid1,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,cuticle,putative stretch-activated Ca2+ channel protein,,,,reduced virulence,,,yes,,,,,wild type,,no,calcofluor white; ethylene glycol tetraacetic acid (EGTA),calcofluor white: CHEBI:50011; ethylene glycol tetraacetic acid (EGTA): CAS:67-42-5,,,,,gene deletion: full; gene complementation,,,YVS,30617534,PubMed,10.1007/s00253-018-09589-8,Appl Microbiol Biotechnol. 2019 Jan 7,yueqingcao@cqu.edu.cn,"ΔMaMid1 had decreased virulence, with defects in the ability to penetrate the host cuticle.",M Xie 2019,2019,1 gene,"Xie-2019-Mid1 affects ion transport, cell wall",BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13141,PHI:8783,UniProt,P60317,GenBank,AAL20761,,,LT2,ProQ,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,cervical adenocarcinoma cell line,RNA chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30602583,PubMed,10.1128/mBio.02504-18,MBio. 2019 Jan 2;10(1). pii: e02504-18,joerg.vogel@uniwuerzburg.de,"ProQ was required for optimal virulence gene expression in Salmonella and directly compares the molecular consequences of loss of function of ProQ with those of the primary enterobacterial sRNA-binding chaperone, Hfq.",A J Westermann 2019,2019,1 gene,Westermann-2019-The Major RNA-Binding Protein,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13142,PHI:8783,UniProt,P60317,GenBank,AAL20761,,,LT2,ProQ,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,RNA chaperone,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30602583,PubMed,10.1128/mBio.02504-18,MBio. 2019 Jan 2;10(1). pii: e02504-18,joerg.vogel@uniwuerzburg.de,"ProQ was required for optimal virulence gene expression in Salmonella and directly compares the molecular consequences of loss of function of ProQ with those of the primary enterobacterial sRNA-binding chaperone, Hfq.",A J Westermann 2019,2019,1 gene,Westermann-2019-The Major RNA-Binding Protein,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13143,PHI:8783,UniProt,P60317,GenBank,AAL20761,,,LT2,ProQ,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,RNA chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30602583,PubMed,10.1128/mBio.02504-18,MBio. 2019 Jan 2;10(1). pii: e02504-18,joerg.vogel@uniwuerzburg.de,"ProQ was required for optimal virulence gene expression in Salmonella and directly compares the molecular consequences of loss of function of ProQ with those of the primary enterobacterial sRNA-binding chaperone, Hfq.",A J Westermann 2019,2019,1 gene,Westermann-2019-The Major RNA-Binding Protein,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13144,PHI:8784,UniProt,J9VKY7,GenBank,AFR92345,,,H99,zfp1 (CNAG_07329),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain; spleen,C2H2 zinc finger protein,,,,reduced virulence,,,,,,,reduced,reduced,,no,SDS; congo red; NaCl; sorbitol; H2O2,SDS: CHEBI:8984; Congo red: CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30630094,PubMed,10.1016/j.fgb.2019.01.002,Fungal Genet Biol. 2019 Jan 7;124:59-72,tongbaoliu@swu.edu.cn,"Zfp1 was essential for sexual reproduction, as both the zfp1Δ mutant and the ZFP1 overexpressed strain no longer produced basidiospores, even though they produced normal mating-specific dikaryotic hyphae.",C L Fan 2019,2019,1 gene,Fan-2019-The Cys2His2 zinc finger protein Zfp1,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13145,PHI:8784,UniProt,J9VKY7,GenBank,AFR92345,,,H99,zfp1 (CNAG_07329),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain; spleen,C2H2 zinc finger protein,,,,reduced virulence,,,,,,,reduced,reduced,,no,SDS; congo red; NaCl; sorbitol; H2O2,SDS: CHEBI:8984; Congo red: CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30630094,PubMed,10.1016/j.fgb.2019.01.002,Fungal Genet Biol. 2019 Jan 7;124:59-72,tongbaoliu@swu.edu.cn,"Zfp1 was essential for sexual reproduction, as both the zfp1Δ mutant and the ZFP1 overexpressed strain no longer produced basidiospores, even though they produced normal mating-specific dikaryotic hyphae.",C L Fan 2019,2019,1 gene,Fan-2019-The Cys2His2 zinc finger protein Zfp1,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13146,PHI:8785,UniProt,C9YKX5,GenBank,CBE03622,,,R20291,hatR (CDR20291_1227),,,,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,TetR family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,30576368,PubMed,10.1371/journal.ppat.1007486,PLoS Pathog. 2018 Dec 21;14(12):e1007486,eric.skaar@vumc.org,HatRT operon senses and detoxifies intracellular heme in C. difficile and was required for full pathogenicity during infection.,R J Knippel 2018,2018,2 genes,Knippel-2018-Heme sensing and detoxification b,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13147,PHI:8786,UniProt,C9YKX4,GenBank,CBE03620,,,R20291,hatT (CDR20291_1226),,,,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,major facilitator superfamily transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,30576368,PubMed,10.1371/journal.ppat.1007486,PLoS Pathog. 2018 Dec 21;14(12):e1007486,eric.skaar@vumc.org,HatRT operon senses and detoxifies intracellular heme in C. difficile and was required for full pathogenicity during infection.,R J Knippel 2018,2018,2 genes,Knippel-2018-Heme sensing and detoxification b,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13148,PHI:8787,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,"candidalysin, a cytolytic peptide toxin",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30622184,PubMed,10.1128/mBio.02221-18,MBio. 2019 Jan 8;10(1). pii: e02221-18,andy.wullaert@ugent.be,"Host gene alteration data available for caspase-1, ASC and Nlrp3. The Ece1III peptide induced IL-1beta secretion from wild-type (WT) macrophages but not from macrophages lacking either caspase-1, ASC or Nlrp3.",O Rogiers 2019,2019,1 gene,Rogiers-2019-Candidalysin Crucially Contribute,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13149,PHI:8788,UniProt,J9VX78,GenBank,AFR98863,,,H99,sho1 (CNAG_05435),chromosome 14,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,putative membrane sensor protein,,,,reduced virulence,,,,,,,,,,no,NaCl; fludioxonil; SDS; KCl; Congo red (CR); calcofluor white (CFW),NaCl: CHEBI:26710; fludioxonil: CHEBI:81763; SDS: CHEBI:8984; KCl: CHEBI:32588; Congo red (CR): CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene mutation; gene complementation,,,YVS,30564211,PubMed,10.3389/fmicb.2018.02958,Front Microbiol. 2018 Dec 4;9:2958,ysbahn@yonsei.ac.kr,"Msb2 was particularly important for the early adaptation to the host's lung environment, whereas Sho1 promoted the growth of fungus during the later time points.",Y S So 2018,2018,2 genes,So-2018-Sho1 and Msb2 Play Complementary but D,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13150,PHI:8789,UniProt,J9VMP5,GenBank,AFR94721,,,H99,msb2 (CNAG_01421),chromosome 5,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,mucin like transmembrane protein,,,,reduced virulence,,,,,,,,,,no,NaCl; fludioxonil; SDS; KCl; Congo red (CR); calcofluor white (CFW),NaCl: CHEBI:26710; fludioxonil: CHEBI:81763; SDS: CHEBI:8984; KCl: CHEBI:32588; Congo red (CR): CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene mutation,,,YVS,30564211,PubMed,10.3389/fmicb.2018.02958,Front Microbiol. 2018 Dec 4;9:2958,ysbahn@yonsei.ac.kr,"Msb2 was particularly important for the early adaptation to the host's lung environment, whereas Sho1 promoted the growth of fungus during the later time points.",Y S So 2018,2018,2 genes,So-2018-Sho1 and Msb2 Play Complementary but D,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13151,PHI:8788,UniProt,J9VX78,GenBank,AFR98863,,,H99,sho1 (CNAG_05435),chromosome 14,,,,,PHI:8789,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,putative membrane sensor protein,,,,reduced virulence,,,,,,,,,,no,NaCl; fludioxonil; SDS; KCl; Congo red (CR); calcofluor white (CFW),NaCl: CHEBI:26710; fludioxonil: CHEBI:81763; SDS: CHEBI:8984; KCl: CHEBI:32588; Congo red (CR): CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene mutation,,,YVS,30564211,PubMed,10.3389/fmicb.2018.02958,Front Microbiol. 2018 Dec 4;9:2958,ysbahn@yonsei.ac.kr,"Msb2 was particularly important for the early adaptation to the host's lung environment, whereas Sho1 promoted the growth of fungus during the later time points.",Y S So 2018,2018,2 genes,So-2018-Sho1 and Msb2 Play Complementary but D,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13152,PHI:8789,UniProt,J9VMP5,GenBank,AFR94721,,,H99,msb2 (CNAG_01421),chromosome 5,,,,,PHI:8788,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,mucin like transmembrane protein,,,,reduced virulence,,,,,,,,,,no,NaCl; fludioxonil; SDS; KCl; Congo red (CR); calcofluor white (CFW),NaCl: CHEBI:26710; fludioxonil: CHEBI:81763; SDS: CHEBI:8984; KCl: CHEBI:32588; Congo red (CR): CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene mutation,,,YVS,30564211,PubMed,10.3389/fmicb.2018.02958,Front Microbiol. 2018 Dec 4;9:2958,ysbahn@yonsei.ac.kr,"Msb2 was particularly important for the early adaptation to the host's lung environment, whereas Sho1 promoted the growth of fungus during the later time points.",Y S So 2018,2018,2 genes,So-2018-Sho1 and Msb2 Play Complementary but D,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13153,PHI:8790,UniProt,B0RMF9,GenBank,CAP53772,,,B100,xopL,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30594633,PubMed,10.1016/j.resmic.2018.12.001,Res Microbiol. 2018 Dec 27. pii: S0923-2508(18)30180-3,czhe@hainu.edu.cn,XopLXcc8004 was required for full virulence of Xcc8004 in Chinese cabbage.,X Yan 2018,2018,1 gene,Yan-2018-A type III effector XopLXcc8004 is vi,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13154,PHI:8790,UniProt,B0RMF9,GenBank,CAP53772,,,B100,xopL,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30594633,PubMed,10.1016/j.resmic.2018.12.001,Res Microbiol. 2018 Dec 27. pii: S0923-2508(18)30180-3,czhe@hainu.edu.cn,XopLXcc8004 down-regulated the pathogenesis/defense related genes to promote Xcc8004 proliferation in A. thaliana.,X Yan 2018,2018,1 gene,Yan-2018-A type III effector XopLXcc8004 is vi,BATCH_089B,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13155,PHI:8791,UniProt,A0A1X9I314,GenBank,ANJ64386,,,JH1301,srtR,,,,,,,1307,Streptococcus suis,,SS9-P10,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneum,stress response transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30687648,PubMed,10.3389/fcimb.2018.00452,Front Cell Infect Microbiol. 2019 Jan 10;8:452,xlyu999@126.com,"SrtR regulated stress tolerance and virulence in S. suis, but was not involved in biofilm formation.",Y Hu 2018,2018,1 gene,Hu-2018-The XRE Family Transcriptional Regulat,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13156,PHI:8791,UniProt,A0A1X9I314,GenBank,ANJ64386,,,JH1301,srtR,,,,,,,1307,Streptococcus suis,,DN13,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneum,stress response transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30687648,PubMed,10.3389/fcimb.2018.00452,Front Cell Infect Microbiol. 2019 Jan 10;8:452,xlyu999@126.com,"SrtR regulated stress tolerance and virulence in S. suis, but was not involved in biofilm formation.",Y Hu 2018,2018,1 gene,Hu-2018-The XRE Family Transcriptional Regulat,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13157,PHI:8792,,no data found,,,,,,Teg41,,Teg41Δ3' (deletion of 24 nucleotides in the 3' region of Teg41),,,,,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30723124,PubMed,10.1128/mBio.02484-18,MBio. 2019 Feb 5;10(1). pii: e02484-18,carrolr3@ohio.edu,"Deleting a 24-nucleotide region from the S. aureus genome, corresponding to the 3' end of Teg41, led to a 10-fold reduction in alpha-PSM-dependent hemolytic activity and attenuation of virulence in a murine abscess model of infection.",R L Zapf 2019,2019,1 gene,Zapf-2019-The Small RNA Teg41 Regulates Expres,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13158,PHI:8792,,no data found,,,,,,Teg41,,Teg41Δ3' (deletion of 24 nucleotides in the 3' region of Teg41),,,,,1280,Staphylococcus aureus,,USA300 AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30723124,PubMed,10.1128/mBio.02484-18,MBio. 2019 Feb 5;10(1). pii: e02484-18,carrolr3@ohio.edu,"Deleting a 24-nucleotide region from the S. aureus genome, corresponding to the 3' end of Teg41, led to a 10-fold reduction in alpha-PSM-dependent hemolytic activity and attenuation of virulence in a murine abscess model of infection.",R L Zapf 2019,2019,1 gene,Zapf-2019-The Small RNA Teg41 Regulates Expres,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13159,PHI:8792,,no data found,,,,,,Teg41,,Teg41Δ3' (deletion of 24 nucleotides in the 3' region of Teg41),,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30723124,PubMed,10.1128/mBio.02484-18,MBio. 2019 Feb 5;10(1). pii: e02484-18,carrolr3@ohio.edu,"Deleting a 24-nucleotide region from the S. aureus genome, corresponding to the 3' end of Teg41, led to a 10-fold reduction in alpha-PSM-dependent hemolytic activity and attenuation of virulence in a murine abscess model of infection.",R L Zapf 2019,2019,1 gene,Zapf-2019-The Small RNA Teg41 Regulates Expres,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13160,PHI:8792,,no data found,,,,,,Teg41,,Teg41Δ3' (deletion of 24 nucleotides in the 3' region of Teg41),,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30723124,PubMed,10.1128/mBio.02484-18,MBio. 2019 Feb 5;10(1). pii: e02484-18,carrolr3@ohio.edu,"Deleting a 24-nucleotide region from the S. aureus genome, corresponding to the 3' end of Teg41, led to a 10-fold reduction in alpha-PSM-dependent hemolytic activity and attenuation of virulence in a murine abscess model of infection.",R L Zapf 2019,2019,1 gene,Zapf-2019-The Small RNA Teg41 Regulates Expres,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13161,PHI:8792,,no data found,,,,,,Teg41,,Teg41Δ3' (deletion of 24 nucleotides in the 3' region of Teg41),,,,,1280,Staphylococcus aureus,,UAMS-1,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,subcutaneous tissue,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30723124,PubMed,10.1128/mBio.02484-18,MBio. 2019 Feb 5;10(1). pii: e02484-18,carrolr3@ohio.edu,"Deleting a 24-nucleotide region from the S. aureus genome, corresponding to the 3' end of Teg41, led to a 10-fold reduction in alpha-PSM-dependent hemolytic activity and attenuation of virulence in a murine abscess model of infection.",R L Zapf 2019,2019,1 gene,Zapf-2019-The Small RNA Teg41 Regulates Expres,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13162,PHI:8792,,no data found,,,,,,Teg41,,Teg41Δ3' (deletion of 24 nucleotides in the 3' region of Teg41),,,,,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,blood,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30723124,PubMed,10.1128/mBio.02484-18,MBio. 2019 Feb 5;10(1). pii: e02484-18,carrolr3@ohio.edu,"Deleting a 24-nucleotide region from the S. aureus genome, corresponding to the 3' end of Teg41, led to a 10-fold reduction in alpha-PSM-dependent hemolytic activity and attenuation of virulence in a murine abscess model of infection.",R L Zapf 2019,2019,1 gene,Zapf-2019-The Small RNA Teg41 Regulates Expres,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13163,PHI:8792,,no data found,,,,,,Teg41,,Teg41Δ3' (deletion of 24 nucleotides in the 3' region of Teg41),,,,,1280,Staphylococcus aureus,,USA300 AH1263,skin infection; food poisoning; respiratory disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,blood,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30723124,PubMed,10.1128/mBio.02484-18,MBio. 2019 Feb 5;10(1). pii: e02484-18,carrolr3@ohio.edu,"Deleting a 24-nucleotide region from the S. aureus genome, corresponding to the 3' end of Teg41, led to a 10-fold reduction in alpha-PSM-dependent hemolytic activity and attenuation of virulence in a murine abscess model of infection.",R L Zapf 2019,2019,1 gene,Zapf-2019-The Small RNA Teg41 Regulates Expres,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13164,PHI:8792,,no data found,,,,,,Teg41,,Teg41Δ3' (deletion of 24 nucleotides in the 3' region of Teg41),,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,blood,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30723124,PubMed,10.1128/mBio.02484-18,MBio. 2019 Feb 5;10(1). pii: e02484-18,carrolr3@ohio.edu,"Deleting a 24-nucleotide region from the S. aureus genome, corresponding to the 3' end of Teg41, led to a 10-fold reduction in alpha-PSM-dependent hemolytic activity and attenuation of virulence in a murine abscess model of infection.",R L Zapf 2019,2019,1 gene,Zapf-2019-The Small RNA Teg41 Regulates Expres,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13165,PHI:8792,,no data found,,,,,,Teg41,,Teg41Δ3' (deletion of 24 nucleotides in the 3' region of Teg41),,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,blood,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30723124,PubMed,10.1128/mBio.02484-18,MBio. 2019 Feb 5;10(1). pii: e02484-18,carrolr3@ohio.edu,"Deleting a 24-nucleotide region from the S. aureus genome, corresponding to the 3' end of Teg41, led to a 10-fold reduction in alpha-PSM-dependent hemolytic activity and attenuation of virulence in a murine abscess model of infection.",R L Zapf 2019,2019,1 gene,Zapf-2019-The Small RNA Teg41 Regulates Expres,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13166,PHI:8792,,no data found,,,,,,Teg41,,Teg41Δ3' (deletion of 24 nucleotides in the 3' region of Teg41),,,,,1280,Staphylococcus aureus,,UAMS-1,skin infection; food poisoning; respiratory disease,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,blood,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30723124,PubMed,10.1128/mBio.02484-18,MBio. 2019 Feb 5;10(1). pii: e02484-18,carrolr3@ohio.edu,"Deleting a 24-nucleotide region from the S. aureus genome, corresponding to the 3' end of Teg41, led to a 10-fold reduction in alpha-PSM-dependent hemolytic activity and attenuation of virulence in a murine abscess model of infection.",R L Zapf 2019,2019,1 gene,Zapf-2019-The Small RNA Teg41 Regulates Expres,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13167,PHI:8793,UniProt,J9VVM2,GenBank,AFR98313,,,H99,Cdk8 (CNAG_06086),chromosome 12,,,Ssn8 (CNAG_00440),UniProt: J9VE41; GenBank: AFR92572,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,cyclin-dependent kinase,,,,reduced virulence,yes,,,,,,,reduced,,no,Congo red; calcofluor white; SDS; ethanol; NaNO2; H2O2; sorbitol,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; ethanol: CHEBI:16236; NaNO2: CHEBI:78870; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30755515,PubMed,10.1128/mBio.02818-18,MBio. 2019 Feb 12;10(1). pii: e02818-18,doering@wustl.edu,Deletion of CDK8 yielded altered mitochondrial morphology and the dysregulation of genes involved in oxidation-reduction processes.,A L Chang 2019,2019,2 genes,Chang-2019-Cdk8 and Ssn801 Regulate Oxidative,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13168,PHI:8794,UniProt,J9VE41,GenBank,AFR92572,,,H99,Ssn8 (CNAG_00440),chromosome 1,,,Cdk8 (CNAG_06086),UniProt: J9VVM2; GenBank: AFR98313,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,cyclin C,,,,reduced virulence,no,,,,,,,reduced,,no,Congo red; calcofluor white; SDS; ethanol; NaNO2; H2O2; sorbitol,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; ethanol: CHEBI:16236; NaNO2: CHEBI:78870; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30755515,PubMed,10.1128/mBio.02818-18,MBio. 2019 Feb 12;10(1). pii: e02818-18,doering@wustl.edu,"Lack of Ssn801 caused intracellular survival defects contingent on oxidative stress susceptibility, alterations in mitochondrial morphology and function.",A L Chang 2019,2019,2 genes,Chang-2019-Cdk8 and Ssn801 Regulate Oxidative,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13169,PHI:8793,UniProt,J9VVM2,GenBank,AFR98313,,,H99,Cdk8 (CNAG_06086),chromosome 12,,,Ssn8 (CNAG_00440),UniProt: J9VE41; GenBank: AFR92572,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,cyclin-dependent kinase,,,,reduced virulence,yes,,,,,,,reduced,,no,Congo red; calcofluor white; SDS; ethanol; NaNO2; H2O2; sorbitol,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; ethanol: CHEBI:16236; NaNO2: CHEBI:78870; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30755515,PubMed,10.1128/mBio.02818-18,MBio. 2019 Feb 12;10(1). pii: e02818-18,doering@wustl.edu,Deletion of CDK8 yielded altered mitochondrial morphology and the dysregulation of genes involved in oxidation-reduction processes.,A L Chang 2019,2019,2 genes,Chang-2019-Cdk8 and Ssn801 Regulate Oxidative,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13170,PHI:8793,UniProt,J9VVM2,GenBank,AFR98313,,,H99,Cdk8 (CNAG_06086),chromosome 12,,,Ssn8 (CNAG_00440),UniProt: J9VE41; GenBank: AFR92572,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain,cyclin-dependent kinase,,,,reduced virulence,yes,,,,,,,reduced,,no,Congo red; calcofluor white; SDS; ethanol; NaNO2; H2O2; sorbitol,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; ethanol: CHEBI:16236; NaNO2: CHEBI:78870; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30755515,PubMed,10.1128/mBio.02818-18,MBio. 2019 Feb 12;10(1). pii: e02818-18,doering@wustl.edu,Deletion of CDK8 yielded altered mitochondrial morphology and the dysregulation of genes involved in oxidation-reduction processes.,A L Chang 2019,2019,2 genes,Chang-2019-Cdk8 and Ssn801 Regulate Oxidative,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13171,PHI:8795,UniProt,J9QZI8,GenBank,AFR34829,,,RA-CH-1,gldK (B739_0222),,,,,,,34085,Riemerella anatipestifer,1228997,RA-CH-1,septicemia anserum exsudativa,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood; liver; brain,gliding motility-associated lipoprotein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30690566,PubMed,10.3382/ps/pez028,Poult Sci. 2019 Jan 25,chenganchun@vip.163.com,Deletion of the gldK gene decreased the survival rate of R.Anatipestifer-infected ducks.,H Yuan 2019,2019,1 gene,Yuan-2019-Role of the gldK gene in the virulen,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13172,PHI:8795,UniProt,J9QZI8,GenBank,AFR34829,,,RA-CH-1,gldK (B739_0222),,,,,,,34085,Riemerella anatipestifer,1228997,RA-CH-1,septicemia anserum exsudativa,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,spleen; heart,gliding motility-associated lipoprotein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30690566,PubMed,10.3382/ps/pez028,Poult Sci. 2019 Jan 25,chenganchun@vip.163.com,Deletion of the gldK gene decreased the survival rate of R.Anatipestifer-infected ducks.,H Yuan 2019,2019,1 gene,Yuan-2019-Role of the gldK gene in the virulen,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13173,PHI:8795,UniProt,J9QZI8,GenBank,AFR34829,,,RA-CH-1,gldK (B739_0222),,,,,,,34085,Riemerella anatipestifer,1228997,RA-CH-1,septicemia anserum exsudativa,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,gliding motility-associated lipoprotein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30690566,PubMed,10.3382/ps/pez028,Poult Sci. 2019 Jan 25,chenganchun@vip.163.com,Inactivation of the gldK gene decreased the adhesion and invasion abilities in Vero cells.,H Yuan 2019,2019,1 gene,Yuan-2019-Role of the gldK gene in the virulen,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13174,PHI:8796,UniProt,Q6FM24,GenBank,XP_448720,,,CBS 138,vph2 (CAGL0K11594g),chromosome K,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; liver,assembly factor of V-ATPase,,,,reduced virulence,,,,,,,,,,no,bafilomycin B1; fluconazole; voriconazole; amphotericin B; FK506; NaCl; CaCl2; MnCl2; ZnCl2; desferrioxamine; bathophenanthroline disulfonate,"bafilomycin B1 CAS no.: CAS:88899-56-3; fluconazole: CHEBI:46081; voriconazole: CHEBI:10023; amphotericin B: CHEBI:2682; FK506,  NaCl: CHEBI:26710; CaCl2: CHEBI:3312; ZnCl2: CHEBI:49976; MnCl2: CHEBI:63041; desferrioxamine: CHEBI:4356; bathophenanthroline disulfonate: CHEBI:78158",,,,,gene deletion: full; gene complementation,,,YVS,30673768,PubMed,10.1371/journal.pone.0210883,PLoS One. 2019 Jan 23;14(1):e0210883,taiga-m@nagasaki-u.ac.jp,Loss of Vph2 resulted in increased fungal sensitivity to various environmental stresses.,A Minematsu 2019,2019,1 gene,Minematsu-2019-Vacuolar proton-translocating A,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13175,PHI:8797,,no data found,GenBank,OWY52468,,,Z7,metR,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Ponkan,,,leaf,"methionine biosynthesis regulator, a bZip transcription factor",,,methionine metabolism,loss of pathogenicity,,,yes,,,reduced,,reduced; aberrant,,no,H2O2; cumyl hydroperoxide; diethyl maleate; NaCl; FeSO4; CuSO4,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; diethyl maleate: CHEBI:68508; NaCl: CHEBI:26710; FeSO4: CHEBI:75832; CuSO4: CHEBI:23414,,,,,gene disruption; gene complementation,,,YVS,30642471,PubMed,10.1016/j.micres.2018.11.007,Microbiol Res. 2019 Feb;219:94-109,hyli@zju.edu.cn,ΔAaMetR mutant on their tangerine host could neither penetrate nor cause disease.,Y Gai 2019,2019,1 gene,Gai-2019-The methionine biosynthesis regulator,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13176,PHI:8797,,no data found,GenBank,OWY52468,,,Z7,metR,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,"methionine biosynthesis regulator, a bZip transcription factor",,,methionine metabolism,loss of pathogenicity,,,yes,,,reduced,,reduced; aberrant,,no,H2O2; cumyl hydroperoxide; diethyl maleate; NaCl; FeSO4; CuSO4,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; diethyl maleate: CHEBI:68508; NaCl: CHEBI:26710; FeSO4: CHEBI:75832; CuSO4: CHEBI:23414,,,,,gene disruption; gene complementation,,,YVS,30642471,PubMed,10.1016/j.micres.2018.11.007,Microbiol Res. 2019 Feb;219:94-109,hyli@zju.edu.cn,ΔAaMetR mutant on their tangerine host could neither penetrate nor cause disease.,Y Gai 2019,2019,1 gene,Gai-2019-The methionine biosynthesis regulator,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13177,PHI:8798,UniProt,Q5ZZ51,GenBank,AAU26267,,,Philadelphia 1,RavD (Lpg0160),,,,,,,446,Legionella pneumophila,,Lp01,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30733336,PubMed,10.1074/jbc.RA118.007086,J Biol Chem. 2019 Feb 7. pii: jbc.RA118.007086,neunr@udel.edu,ΔRavD was dispensable for intracellular growth.,C M Pike 2019,2019,2 genes,Pike-2019-Legionella effector RavD binds phosp,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13178,PHI:8798,UniProt,Q5ZZ51,GenBank,AAU26267,,,Philadelphia 1,RavD (Lpg0160),,,,,,,446,Legionella pneumophila,,Lp01,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30733336,PubMed,10.1074/jbc.RA118.007086,J Biol Chem. 2019 Feb 7. pii: jbc.RA118.007086,neunr@udel.edu,ΔRavD was dispensable for intracellular growth.,C M Pike 2019,2019,2 genes,Pike-2019-Legionella effector RavD binds phosp,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13179,PHI:8799,UniProt,Q5ZS33,GenBank,AAU28744,,,Philadelphia 1,DotA,,,,,,,446,Legionella pneumophila,,Lp01,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,conjugal transfer/type IV secretion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30733336,PubMed,10.1074/jbc.RA118.007086,J Biol Chem. 2019 Feb 7. pii: jbc.RA118.007086,neunr@udel.edu,ΔdotA showed impaired growth in both host cell types.,C M Pike 2019,2019,2 genes,Pike-2019-Legionella effector RavD binds phosp,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13180,PHI:8799,UniProt,Q5ZS33,GenBank,AAU28744,,,Philadelphia 1,DotA,,,,,,,446,Legionella pneumophila,,Lp01,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,conjugal transfer/type IV secretion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30733336,PubMed,10.1074/jbc.RA118.007086,J Biol Chem. 2019 Feb 7. pii: jbc.RA118.007086,neunr@udel.edu,ΔdotA showed impaired growth in both host cell types.,C M Pike 2019,2019,2 genes,Pike-2019-Legionella effector RavD binds phosp,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13181,PHI:8800,,no data found,,,,,,S5nA,,,,,,,1314,Streptococcus pyogenes,,serotype M6 strain K006,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,surface-associated 5'-nucleotidase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30703118,PubMed,10.1371/journal.pone.0211074,PLoS One. 2019 Jan 31;14(1):e0211074,tomas.fiedler@med.uni-rostock.de,"The deletion of the S5nA gene does not significantly affect growth in human blood, evasion of phagocytosis by neutrophils, formation of biofilms and virulence in an infection model with larvae of the greater wax moth Galleria mellonella in S. pyogenes serotypes M6, M18 and M49.",M L Dangel 2019,2019,1 gene,Dangel-2019-The 5'-nucleotidase S5nA is dispen,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13182,PHI:8800,,no data found,,,,,,S5nA,,,,,,,1314,Streptococcus pyogenes,186103,serotype M18 strain MGAS8232,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,surface-associated 5'-nucleotidase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30703118,PubMed,10.1371/journal.pone.0211074,PLoS One. 2019 Jan 31;14(1):e0211074,tomas.fiedler@med.uni-rostock.de,"The deletion of the S5nA gene does not significantly affect growth in human blood, evasion of phagocytosis by neutrophils, formation of biofilms and virulence in an infection model with larvae of the greater wax moth Galleria mellonella in S. pyogenes serotypes M6, M18 and M49.",M L Dangel 2019,2019,1 gene,Dangel-2019-The 5'-nucleotidase S5nA is dispen,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13183,PHI:8800,,no data found,,,,,,S5nA,,,,,,,1314,Streptococcus pyogenes,294934,serotype M49 strain M49 591,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,surface-associated 5'-nucleotidase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30703118,PubMed,10.1371/journal.pone.0211074,PLoS One. 2019 Jan 31;14(1):e0211074,tomas.fiedler@med.uni-rostock.de,"The deletion of the S5nA gene does not significantly affect growth in human blood, evasion of phagocytosis by neutrophils, formation of biofilms and virulence in an infection model with larvae of the greater wax moth Galleria mellonella in S. pyogenes serotypes M6, M18 and M49.",M L Dangel 2019,2019,1 gene,Dangel-2019-The 5'-nucleotidase S5nA is dispen,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13184,PHI:8800,,no data found,,,,,,S5nA,,,,,,,1314,Streptococcus pyogenes,,serotype M6 strain K006,infection,primates,9606,Homo sapiens (related: human),,,,blood,surface-associated 5'-nucleotidase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30703118,PubMed,10.1371/journal.pone.0211074,PLoS One. 2019 Jan 31;14(1):e0211074,tomas.fiedler@med.uni-rostock.de,"The deletion of the S5nA gene does not significantly affect growth in human blood, evasion of phagocytosis by neutrophils, formation of biofilms and virulence in an infection model with larvae of the greater wax moth Galleria mellonella in S. pyogenes serotypes M6, M18 and M49.",M L Dangel 2019,2019,1 gene,Dangel-2019-The 5'-nucleotidase S5nA is dispen,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13185,PHI:8800,,no data found,,,,,,S5nA,,,,,,,1314,Streptococcus pyogenes,186103,serotype M18 strain MGAS8232,infection,primates,9606,Homo sapiens (related: human),,,,blood,surface-associated 5'-nucleotidase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30703118,PubMed,10.1371/journal.pone.0211074,PLoS One. 2019 Jan 31;14(1):e0211074,tomas.fiedler@med.uni-rostock.de,"The deletion of the S5nA gene does not significantly affect growth in human blood, evasion of phagocytosis by neutrophils, formation of biofilms and virulence in an infection model with larvae of the greater wax moth Galleria mellonella in S. pyogenes serotypes M6, M18 and M49.",M L Dangel 2019,2019,1 gene,Dangel-2019-The 5'-nucleotidase S5nA is dispen,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13186,PHI:8800,,no data found,,,,,,S5nA,,,,,,,1314,Streptococcus pyogenes,294934,serotype M49 strain M49 591,infection,primates,9606,Homo sapiens (related: human),,,,blood,surface-associated 5'-nucleotidase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30703118,PubMed,10.1371/journal.pone.0211074,PLoS One. 2019 Jan 31;14(1):e0211074,tomas.fiedler@med.uni-rostock.de,"The deletion of the S5nA gene does not significantly affect growth in human blood, evasion of phagocytosis by neutrophils, formation of biofilms and virulence in an infection model with larvae of the greater wax moth Galleria mellonella in S. pyogenes serotypes M6, M18 and M49.",M L Dangel 2019,2019,1 gene,Dangel-2019-The 5'-nucleotidase S5nA is dispen,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13187,PHI:8801,UniProt,Q5VDC5,GenBank,AAS90001,,,BN008,hexA,,,,,,,5059,Aspergillus flavus,,CA14 PTS,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,hexagonal peroxisome protein,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced; aberrant,,wild type,,no,Congo red; calcofluor white; SDS; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,30744561,PubMed,10.1186/s12867-019-0121-3,BMC Mol Biol. 2019 Feb 11;20(1):4,wshyyl@sina.com,The deletion of hexA gene reduced the production of asexual spores and lessened virulence on peanuts and maize seeds markedly.,J Yuan 2019,2019,1 gene,"Yuan-2019-HexA is required for growth, aflatox",BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13188,PHI:8801,UniProt,Q5VDC5,GenBank,AAS90001,,,BN008,hexA,,,,,,,5059,Aspergillus flavus,,CA14 PTS,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,kernel,hexagonal peroxisome protein,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced; aberrant,,wild type,,no,Congo red; calcofluor white; SDS; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,30744561,PubMed,10.1186/s12867-019-0121-3,BMC Mol Biol. 2019 Feb 11;20(1):4,wshyyl@sina.com,The deletion of hexA gene reduced the production of asexual spores and lessened virulence on peanuts and maize seeds markedly.,J Yuan 2019,2019,1 gene,"Yuan-2019-HexA is required for growth, aflatox",BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13189,PHI:8802,UniProt,A0A125YWL1,GenBank,EPT29482,,,ME49,MIC13,chromosome VIIb,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,microneme protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30635773,PubMed,10.1007/s00436-018-06197-3,Parasitol Res. 2019 Jan 11,zhaojunlong@mail.hzau.edu.cn,"Under stress conditions, such as high pH or oxygen limitation, MIC13-disrupted parasites showed significantly slower growth rates compared to the parental strains, suggesting that it was required for optimal parasite growth under bradyzoite-inducing or stress conditions.",S Ye 2019,2019,1 gene,Ye-2019-Micronemal protein 13 contributes to t,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13190,PHI:8802,UniProt,A0A125YWL1,GenBank,EPT29482,,,ME49,MIC13,chromosome VIIb,,,,,,5811,Toxoplasma gondii,508771,type II strain ME49,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,microneme protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,30635773,PubMed,10.1007/s00436-018-06197-3,Parasitol Res. 2019 Jan 11,zhaojunlong@mail.hzau.edu.cn,"Under stress conditions, such as high pH or oxygen limitation, MIC13-disrupted parasites showed significantly slower growth rates compared to the parental strains, suggesting that it was required for optimal parasite growth under bradyzoite-inducing or stress conditions.",S Ye 2019,2019,1 gene,Ye-2019-Micronemal protein 13 contributes to t,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13191,PHI:8802,UniProt,A0A125YWL1,GenBank,EPT29482,,,ME49,MIC13,chromosome VIIb,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,microneme protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30635773,PubMed,10.1007/s00436-018-06197-3,Parasitol Res. 2019 Jan 11,zhaojunlong@mail.hzau.edu.cn,"Under stress conditions, such as high pH or oxygen limitation, MIC13-disrupted parasites showed significantly slower growth rates compared to the parental strains, suggesting that it was required for optimal parasite growth under bradyzoite-inducing or stress conditions.",S Ye 2019,2019,1 gene,Ye-2019-Micronemal protein 13 contributes to t,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13192,PHI:8802,UniProt,A0A125YWL1,GenBank,EPT29482,,,ME49,MIC13,chromosome VIIb,,,,,,5811,Toxoplasma gondii,508771,type II strain ME49,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,microneme protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,30635773,PubMed,10.1007/s00436-018-06197-3,Parasitol Res. 2019 Jan 11,zhaojunlong@mail.hzau.edu.cn,"Under stress conditions, such as high pH or oxygen limitation, MIC13-disrupted parasites showed significantly slower growth rates compared to the parental strains, suggesting that it was required for optimal parasite growth under bradyzoite-inducing or stress conditions.",S Ye 2019,2019,1 gene,Ye-2019-Micronemal protein 13 contributes to t,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13193,PHI:8803,UniProt,I1RIL9,GenBank,CEF78501,,,PH-1,FgShyC (FGSG_03657),chromosome 2,,,,,,5518,Fusarium graminearum,,NRRL 46422,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Spring wheat,,,inflorescence,putative salicylate hydroxylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30671040,PubMed,10.3389/fmicb.2018.03219,Front Microbiol. 2019 Jan 8;9:3219,guixia.hao@ars.usda.gov,Virulence assays revealed that deletion of FgShy1 alone was not sufficient to affect FHB severity.,G Hao 2018,2018,1 gene,Hao-2018-Characterization of a Fusarium gramin,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13194,PHI:8803,UniProt,I1RIL9,GenBank,CEF78501,,,PH-1,FgShyC (FGSG_03657),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Spring wheat,,,inflorescence,putative salicylate hydroxylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30671040,PubMed,10.3389/fmicb.2018.03219,Front Microbiol. 2019 Jan 8;9:3219,guixia.hao@ars.usda.gov,Virulence assays revealed that deletion of FgShy1 alone was not sufficient to affect FHB severity.,G Hao 2018,2018,1 gene,Hao-2018-Characterization of a Fusarium gramin,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13195,PHI:8804,UniProt,E9ESA9,GenBank,EFZ01626,,,ARSEF 23,MrSVP (EFZ01626),,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemolymph,secreted virulence-associated protein,,,,reduced virulence,,no,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30691387,PubMed,10.1186/s12866-019-1396-8,BMC Microbiol. 2019 Jan 28;19(1):25,bhuang@ahau.edu.cn,Conidial germination rate of the ΔMrSVP mutant fungi dramatically decreased after heat shock treatment in a thermotolerance test.,T Xie 2019,2019,1 gene,"Xie-2019-MrSVP, a secreted virulence-associate",BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13196,PHI:8805,UniProt,A0R5R2,GenBank,ABK71860,,,MC2 155,MSMEG_6281,,,,,,,1772,Mycolicibacterium smegmatis,,,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,peptidoglycan amidase,,,,reduced virulence,,,,,,,,,,no,crystal violet; SDS,crystal violet: CHEBI:41688; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30685363,PubMed,10.1016/j.micpath.2019.01.013,Microb Pathog. 2019 Mar;128:405-413,jiangtaodl@163.com,"MSMEG_6281 inactivation in the M sm-ΔM_6281 infected group caused less mycobacterial colonization, reduced pathological signs, decreased the anti-microbial enzymes production including iNOS and β-defensins in mouse lungs.",J He 2019,2019,1 gene,"He-2019-Lack of MSMEG_6281, a peptidoglycan am",BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13197,PHI:8806,UniProt,G4MXR2,GenBank,EHA55199,,,70-15,MoChi1 (MGG_08054),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,chitinase,,,,reduced virulence,,,yes,,,,,reduced; aberrant,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30696749,PubMed,10.1104/pp.18.01594,Plant Physiol. 2019 Jan 29. pii: pp.01594.2018,wangzh@fafu.edu.cn,"Host gene alteration data available for OsMBL1. Overexpression of OsMBL1 led to activation of rice defense responsive genes and a chitin-induced reactive oxygen species (ROS) burst, thereby enhancing resistance to M. oryzae and knockdown of OsMBL1 enhances susceptibility of rice plants to M. oryzae.",Y Han 2019,2019,1 gene,Han-2019-A Magnaporthe Chitinase Interacts wit,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13198,PHI:8806,UniProt,G4MXR2,GenBank,EHA55199,,,70-15,MoChi1 (MGG_08054),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. CO-39,,,leaf,chitinase,,,,reduced virulence,,,yes,,,,,reduced; aberrant,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30696749,PubMed,10.1104/pp.18.01594,Plant Physiol. 2019 Jan 29. pii: pp.01594.2018,wangzh@fafu.edu.cn,"Host gene alteration data available for OsMBL1. Overexpression of OsMBL1 led to activation of rice defense responsive genes and a chitin-induced reactive oxygen species (ROS) burst, thereby enhancing resistance to M. oryzae and knockdown of OsMBL1 enhances susceptibility of rice plants to M. oryzae.",Y Han 2019,2019,1 gene,Han-2019-A Magnaporthe Chitinase Interacts wit,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13199,PHI:8807,,no data found,,,,,,loiA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum,low oxygen-induced transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30648612,PubMed,10.1016/j.resmic.2019.01.001,Res Microbiol. 2019 Jan 12. pii: S0923-2508(19)30001-4,fenglu63@126.com,The repression of lon by LoiA contributed to S. Typhimurium invasion of intestinal epithelial cells and virulence in mice.,L Jiang 2019,2019,2 genes,Jiang-2019-LoiA directly represses lon gene ex,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13200,PHI:8807,,no data found,,,,,,loiA,,,,,,PHI:8808,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum,low oxygen-induced transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30648612,PubMed,10.1016/j.resmic.2019.01.001,Res Microbiol. 2019 Jan 12. pii: S0923-2508(19)30001-4,fenglu63@126.com,The repression of lon by LoiA contributed to S. Typhimurium invasion of intestinal epithelial cells and virulence in mice.,L Jiang 2019,2019,2 genes,Jiang-2019-LoiA directly represses lon gene ex,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13201,PHI:8808,UniProt,A0A0F6AXS9,GenBank,ACY87051,,,14028S,lon,,,,,,PHI:8807,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum,ATP-dependent protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30648612,PubMed,10.1016/j.resmic.2019.01.001,Res Microbiol. 2019 Jan 12. pii: S0923-2508(19)30001-4,fenglu63@126.com,The repression of lon by LoiA contributed to S. Typhimurium invasion of intestinal epithelial cells and virulence in mice.,L Jiang 2019,2019,2 genes,Jiang-2019-LoiA directly represses lon gene ex,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13202,PHI:8807,,no data found,,,,,,loiA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,low oxygen-induced transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30648612,PubMed,10.1016/j.resmic.2019.01.001,Res Microbiol. 2019 Jan 12. pii: S0923-2508(19)30001-4,fenglu63@126.com,The repression of lon by LoiA contributed to S. Typhimurium invasion of intestinal epithelial cells and virulence in mice.,L Jiang 2019,2019,2 genes,Jiang-2019-LoiA directly represses lon gene ex,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13203,PHI:8807,,no data found,,,,,,loiA,,,,,,PHI:8808,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,low oxygen-induced transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30648612,PubMed,10.1016/j.resmic.2019.01.001,Res Microbiol. 2019 Jan 12. pii: S0923-2508(19)30001-4,fenglu63@126.com,The repression of lon by LoiA contributed to S. Typhimurium invasion of intestinal epithelial cells and virulence in mice.,L Jiang 2019,2019,2 genes,Jiang-2019-LoiA directly represses lon gene ex,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13204,PHI:8808,UniProt,A0A0F6AXS9,GenBank,ACY87051,,,14028S,lon,,,,,,PHI:8807,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,ATP-dependent protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30648612,PubMed,10.1016/j.resmic.2019.01.001,Res Microbiol. 2019 Jan 12. pii: S0923-2508(19)30001-4,fenglu63@126.com,The repression of lon by LoiA contributed to S. Typhimurium invasion of intestinal epithelial cells and virulence in mice.,L Jiang 2019,2019,2 genes,Jiang-2019-LoiA directly represses lon gene ex,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13205,PHI:8807,,no data found,,,,,,loiA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,low oxygen-induced transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30648612,PubMed,10.1016/j.resmic.2019.01.001,Res Microbiol. 2019 Jan 12. pii: S0923-2508(19)30001-4,fenglu63@126.com,LoiA did not influence lon expression during S. Typhimurium growth in macrophages.,L Jiang 2019,2019,2 genes,Jiang-2019-LoiA directly represses lon gene ex,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13206,PHI:8809,UniProt,A0A411NN20,,,,,,RxLR207,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,30703564,PubMed,10.1016/j.molp.2019.01.018,Mol Plant. 2019 Jan 28. pii: S1674-2052(19)30024-3,ddou@njau.edu.cn,RxLR207-transgenic plants exhibited enhanced ROS-mediated resistance and cell death.,Q Li 2019,2019,1 gene,Li-2019-A Phytophthora capsici effector target,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13207,PHI:8809,UniProt,A0A411NN20,,,,,,RxLR207,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30703564,PubMed,10.1016/j.molp.2019.01.018,Mol Plant. 2019 Jan 28. pii: S1674-2052(19)30024-3,ddou@njau.edu.cn,RxLR207 was indispensable for pathogen infection and was involved in transition from biotrophic to necrotrophic stage.,Q Li 2019,2019,1 gene,Li-2019-A Phytophthora capsici effector target,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13208,PHI:8809,UniProt,A0A411NN20,,,,,,RxLR207,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30703564,PubMed,10.1016/j.molp.2019.01.018,Mol Plant. 2019 Jan 28. pii: S1674-2052(19)30024-3,ddou@njau.edu.cn,RxLR207 was indispensable for pathogen infection and was involved in transition from biotrophic to necrotrophic stage.,Q Li 2019,2019,1 gene,Li-2019-A Phytophthora capsici effector target,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13209,PHI:8809,UniProt,A0A411NN20,,,,,,RxLR207,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30703564,PubMed,10.1016/j.molp.2019.01.018,Mol Plant. 2019 Jan 28. pii: S1674-2052(19)30024-3,ddou@njau.edu.cn,RxLR207 was indispensable for pathogen infection and was involved in transition from biotrophic to necrotrophic stage.,Q Li 2019,2019,1 gene,Li-2019-A Phytophthora capsici effector target,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13210,PHI:8809,UniProt,A0A411NN20,,,,,,RxLR207,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30703564,PubMed,10.1016/j.molp.2019.01.018,Mol Plant. 2019 Jan 28. pii: S1674-2052(19)30024-3,ddou@njau.edu.cn,RxLR207-transgenic plants exhibited enhanced ROS-mediated resistance and cell death.,Q Li 2019,2019,1 gene,Li-2019-A Phytophthora capsici effector target,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13211,PHI:8810,UniProt,Q8ZM34,GenBank,AAL21996,,,LT2,STM3122,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,putative arylsulfatase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30648943,PubMed,10.1099/mic.0.000769,Microbiology. 2019 Jan 16,prasadg@uwm.edu,Mutants lacking STM3122 and STM3124 showed decreased survival in zebrafish.,S Das 2019,2019,2 genes,Das-2019-Dopamine-induced sulfatase and its re,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13212,PHI:8811,UniProt,Q8ZM32,GenBank,AAL21998,,,LT2,STM3124,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,putative response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30648943,PubMed,10.1099/mic.0.000769,Microbiology. 2019 Jan 16,prasadg@uwm.edu,Mutants lacking STM3122 and STM3124 showed decreased survival in zebrafish.,S Das 2019,2019,2 genes,Das-2019-Dopamine-induced sulfatase and its re,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13213,PHI:8812,UniProt,A0A0D5YKF1,GenBank,AKA32424,,,AB5075-UW,CopA (ABUW_2707),,copA::T26,,,,,470,Acinetobacter baumannii,,AB5075_UW,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),SWR,,,nasopharynx epithelium,copper-translocating P-type ATPase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,CuSO4; paraquat,CuSO4: CHEBI:23414; paraquat: CHEBI:34905,,,,,gene mutation,,,YVS,30699983,PubMed,10.3390/ijms20030575,Int J Mol Sci. 2019 Jan 29;20(3). pii: E575,bart.eijkelkamp@adelaide.edu.au,CopA provided a high level of copper resistance and protected the cell against oxidative stress.,S F Alquethamy 2019,2019,1 gene,Alquethamy-2019-The Role of the CopA Copper Ef,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13214,PHI:8812,UniProt,A0A0D5YKF1,GenBank,AKA32424,,,AB5075-UW,CopA (ABUW_2707),,copA::T26,,,,,470,Acinetobacter baumannii,,AB5075_UW,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),SWR,,,nasopharynx; bronchoalveolar lavage fluid; lung,copper-translocating P-type ATPase,,,,reduced virulence,,,,,,,,reduced,,no,CuSO4; paraquat,CuSO4: CHEBI:23414; paraquat: CHEBI:34905,,,,,gene mutation,,,YVS,30699983,PubMed,10.3390/ijms20030575,Int J Mol Sci. 2019 Jan 29;20(3). pii: E575,bart.eijkelkamp@adelaide.edu.au,CopA provided a high level of copper resistance and protected the cell against oxidative stress.,S F Alquethamy 2019,2019,1 gene,Alquethamy-2019-The Role of the CopA Copper Ef,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13215,PHI:8813,UniProt,A0A1D9Q1W2,GenBank,APA08927,,,1980,SsC6TF1 (Sscle04g036970),chromosome 4,,,,,,5180,Sclerotinia sclerotiorum,,Scl02-05,white mold,eudicots,3888,Pisum sativum (related: Pea),cv. PI240515,,,leaf,putative C6 transcription factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30674647,PubMed,10.1128/mSphere.00615-18,mSphere. 2019 Jan 23;4(1). pii: e00615-18,chilvers@msu.edu,"SsC6TF1 was not required for vegetative hyphal growth, but it was a positive regulator for sclerotial development and virulence on pea.",H Sang 2019,2019,1 gene,Sang-2019-A Sclerotinia sclerotiorum Transcrip,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13216,PHI:8813,UniProt,A0A1D9Q1W2,GenBank,APA08927,,,1980,SsC6TF1 (Sscle04g036970),chromosome 4,,,,,,5180,Sclerotinia sclerotiorum,,Scl02-05,white mold,eudicots,3888,Pisum sativum (related: Pea),cv. Lifter,,,leaf,putative C6 transcription factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30674647,PubMed,10.1128/mSphere.00615-18,mSphere. 2019 Jan 23;4(1). pii: e00615-18,chilvers@msu.edu,"SsC6TF1 was not required for vegetative hyphal growth, but it was a positive regulator for sclerotial development and virulence on pea.",H Sang 2019,2019,1 gene,Sang-2019-A Sclerotinia sclerotiorum Transcrip,BATCH_090A,2019-02-01,MC,,,,,,,,,,,,,
,,Record 13217,PHI:8814,,no data found,,,,,,SiiE,,,,,,,28901,Salmonella enterica,149539,serovar Enteritidis strain 90-13-706,salmonellosis,primates,9606,Homo sapiens (related: human),HT-29-MTX cell line,,,HT-29-MTX cell,adhesin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30716138,PubMed,10.1371/journal.ppat.1007566,PLoS Pathog. 2019 Feb 4;15(2):e1007566,K.Strijbis@uu.nl,Host gene alteration data available for MUC1. Invasion through MUC1 was completely abolished in the siiE mutant bacteria.,X Li 2019,2019,1 gene,Li-2019-MUC1 is a receptor for the Salmonella,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13218,PHI:8815,,no data found,,,,,,TgApiAT5-3,,apiAT5-3 Δ188–504,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,apicomplexan amino acid transporter,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30742695,PubMed,10.1371/journal.ppat.1007577,PLoS Pathog. 2019 Feb 11;15(2):e1007577,stefan.broeer@anu.edu.au,"Parasites lacking TgApiAT5-3 were avirulent in mice, and could only grow at extracellular L-Tyr concentrations above ~1 mM, well above the plasma concentration of L-Tyr in mammals.",K E R Parker 2019,2019,1 gene,Parker-2019-The tyrosine transporter of Toxopl,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13219,PHI:8816,UniProt,A0A0D1DWQ2,GenBank,XP_011391476,,,521,Cmu1,chromosome 16,Cmu1-ΔELR,,,,,5270,Ustilago maydis,,AB33,smut,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30651637,PubMed,10.1038/s41586-018-0857-9,Nature. 2019 Jan;565(7741):650-653,gert.bange@synmikro.uni-marburg.de,Host gene alteration data available for kiwellin ZmKWL1. ZmKWL1 inhibited the chorismate mutase activity of Cmu1 but not of Cmu1 that lacks the extensive loop region (Cmu1-ΔELR).,X Han 2019,2019,1 gene,Han-2019-A kiwellin disarms the metabolic acti,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13220,PHI:8817,,no data found,,,,,,aap1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,amino acid permease,,,,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl; KCl; H2O2; SDS; Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30682168,PubMed,10.1371/journal.pone.0211393,PLoS One. 2019 Jan 25;14(1):e0211393,renata.pascon@gmail.com,"Virulence attenuation in the case of the double mutant was due to the combination of low capsule production, and also the inability of the mutants (aap8Δ and aap1Δ/aap2Δ) to properly uptake amino acids at the high temperature.",C L Calvete 2019,2019,4 genes,Calvete-2019-Amino acid permeases in Cryptococ,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13221,PHI:8818,,no data found,,,,,,aap6,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,amino acid permease,,,,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl; KCl; H2O2; SDS; Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30682168,PubMed,10.1371/journal.pone.0211393,PLoS One. 2019 Jan 25;14(1):e0211393,renata.pascon@gmail.com,"Virulence attenuation in the case of the double mutant was due to the combination of low capsule production, and also the inability of the mutants (aap8Δ and aap1Δ/aap2Δ) to properly uptake amino acids at the high temperature.",C L Calvete 2019,2019,4 genes,Calvete-2019-Amino acid permeases in Cryptococ,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13222,PHI:8819,,no data found,,,,,,aap8,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,amino acid permease,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; KCl; H2O2; SDS; Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30682168,PubMed,10.1371/journal.pone.0211393,PLoS One. 2019 Jan 25;14(1):e0211393,renata.pascon@gmail.com,"Virulence attenuation in the case of the double mutant was due to the combination of low capsule production, and also the inability of the mutants (aap8Δ and aap1Δ/aap2Δ) to properly uptake amino acids at the high temperature.",C L Calvete 2019,2019,4 genes,Calvete-2019-Amino acid permeases in Cryptococ,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13223,PHI:8817,,no data found,,,,,,aap1,,,,,,PHI:8820,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,amino acid permease,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; KCl; H2O2; SDS; Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30682168,PubMed,10.1371/journal.pone.0211393,PLoS One. 2019 Jan 25;14(1):e0211393,renata.pascon@gmail.com,"Virulence attenuation in the case of the double mutant was due to the combination of low capsule production, and also the inability of the mutants (aap8Δ and aap1Δ/aap2Δ) to properly uptake amino acids at the high temperature.",C L Calvete 2019,2019,4 genes,Calvete-2019-Amino acid permeases in Cryptococ,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13224,PHI:8820,,no data found,,,,,,aap2,,,,,,PHI:8817,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,amino acid permease,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; KCl; H2O2; SDS; Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,30682168,PubMed,10.1371/journal.pone.0211393,PLoS One. 2019 Jan 25;14(1):e0211393,renata.pascon@gmail.com,"Virulence attenuation in the case of the double mutant was due to the combination of low capsule production, and also the inability of the mutants (aap8Δ and aap1Δ/aap2Δ) to properly uptake amino acids at the high temperature.",C L Calvete 2019,2019,4 genes,Calvete-2019-Amino acid permeases in Cryptococ,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13225,PHI:8821,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30707095,PubMed,10.1099/mic.0.000778,Microbiology. 2019 Feb 1,gloria@biomedicas.unam.mx,"ΔLasR mutant and the ΔlasR–ΔrhlR double mutant showed decreased ability to form biofilm, while the ΔrhlR mutant produced more biofilm than the PAO1 strain.",M P Soto-Aceves 2019,2019,2 genes,Soto-Aceves-2019-Inactivation of the quorum-se,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13226,PHI:8822,UniProt,P54292,GenBank,AAC44036,,,PAO1,rhlR,chromosome 1,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30707095,PubMed,10.1099/mic.0.000778,Microbiology. 2019 Feb 1,gloria@biomedicas.unam.mx,"ΔLasR mutant and the ΔlasR–ΔrhlR double mutant showed decreased ability to form biofilm, while the ΔrhlR mutant produced more biofilm than the PAO1 strain.",M P Soto-Aceves 2019,2019,2 genes,Soto-Aceves-2019-Inactivation of the quorum-se,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13227,PHI:8821,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,PHI:8822,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30707095,PubMed,10.1099/mic.0.000778,Microbiology. 2019 Feb 1,gloria@biomedicas.unam.mx,"ΔLasR mutant and the ΔlasR–ΔrhlR double mutant showed decreased ability to form biofilm, while the ΔrhlR mutant produced more biofilm than the PAO1 strain.",M P Soto-Aceves 2019,2019,2 genes,Soto-Aceves-2019-Inactivation of the quorum-se,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13228,PHI:8822,UniProt,P54292,GenBank,AAC44036,,,PAO1,rhlR,chromosome 1,,,,,PHI:8821,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30707095,PubMed,10.1099/mic.0.000778,Microbiology. 2019 Feb 1,gloria@biomedicas.unam.mx,"ΔLasR mutant and the ΔlasR–ΔrhlR double mutant showed decreased ability to form biofilm, while the ΔrhlR mutant produced more biofilm than the PAO1 strain.",M P Soto-Aceves 2019,2019,2 genes,Soto-Aceves-2019-Inactivation of the quorum-se,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13229,PHI:8823,,no data found,GenBank,PTC37135,,,CLJ1,sagS,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,,sensor histidine kinase/response regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,tobramycin,tobramycin: CHEBI:28864,,,,,gene mutation; gene complementation,,,YVS,30710463,PubMed,10.1111/mmi.14215,Mol Microbiol. 2019 Feb 2,ksauer@binghamton.edu,Mutation of residue D105A enhanced the susceptibility of P. aeruginosa to tobramycin treatment in the murine chronic pneumonia model.,J Dingemans 2019,2019,1 gene,Dingemans-2019-Controlling chronic Pseudomonas,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13230,PHI:8823,,no data found,GenBank,PTC37135,,,CLJ1,sagS,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,sensor histidine kinase/response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,tobramycin,tobramycin: CHEBI:28864,,,,,gene mutation; gene complementation,,,YVS,30710463,PubMed,10.1111/mmi.14215,Mol Microbiol. 2019 Feb 2,ksauer@binghamton.edu,Mutation of residue D105A enhanced the susceptibility of P. aeruginosa to tobramycin treatment in the murine chronic pneumonia model.,J Dingemans 2019,2019,1 gene,Dingemans-2019-Controlling chronic Pseudomonas,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13231,PHI:8823,,no data found,GenBank,PTC37135,,,CLJ1,sagS,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,sensor histidine kinase/response regulator,,,,reduced virulence,,,,,,,,wild type,,no,tobramycin,tobramycin: CHEBI:28864,,,,,gene mutation; gene complementation,,,YVS,30710463,PubMed,10.1111/mmi.14215,Mol Microbiol. 2019 Feb 2,ksauer@binghamton.edu,Mutation of residue D105A enhanced the susceptibility of P. aeruginosa to tobramycin treatment in the murine chronic pneumonia model.,J Dingemans 2019,2019,1 gene,Dingemans-2019-Controlling chronic Pseudomonas,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13232,PHI:8823,,no data found,GenBank,PTC37135,,,CLJ1,sagS,,ΔsagS::sagS_L154A,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,sensor histidine kinase/response regulator,,,,reduced virulence,,,,,,,,wild type,,no,tobramycin,tobramycin: CHEBI:28864,,,,,gene mutation; gene complementation,,,YVS,30710463,PubMed,10.1111/mmi.14215,Mol Microbiol. 2019 Feb 2,ksauer@binghamton.edu,Mutation of residue D105A enhanced the susceptibility of P. aeruginosa to tobramycin treatment in the murine chronic pneumonia model.,J Dingemans 2019,2019,1 gene,Dingemans-2019-Controlling chronic Pseudomonas,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13233,PHI:8823,,no data found,GenBank,PTC37135,,,CLJ1,sagS,,ΔsagS::sagS_L154A,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,sensor histidine kinase/response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,tobramycin,tobramycin: CHEBI:28864,,,,,gene mutation; gene complementation,,,YVS,30710463,PubMed,10.1111/mmi.14215,Mol Microbiol. 2019 Feb 2,ksauer@binghamton.edu,Mutation of residue D105A enhanced the susceptibility of P. aeruginosa to tobramycin treatment in the murine chronic pneumonia model.,J Dingemans 2019,2019,1 gene,Dingemans-2019-Controlling chronic Pseudomonas,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13234,PHI:8824,UniProt,B4E6H5,GenBank,CAR52750,,,J2315,bcal2449,chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative cyclic-di-GMP signaling protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13235,PHI:8825,UniProt,B4E7D8,GenBank,CAR50741,,,J2315,bcal0430,chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13236,PHI:8826,UniProt,B4E8Q7,GenBank,CAR51933,,,J2315,bcal1635,chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative cyclic-di-GMP signaling protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13237,PHI:8827,UniProt,B4EBK3,GenBank,CAR52276,,,J2315,bcal1975,chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13238,PHI:8828,UniProt,B4EA36,GenBank,CAR51324,,,J2315,bcal2852,chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13239,PHI:8829,UniProt,B4EM50,GenBank,CAR54608,,,J2315,bcam0748,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13240,PHI:8830,UniProt,B4EGR6,GenBank,CAR55017,,,J2315,bcam1161,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative cyclic-di-GMP signaling protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13241,PHI:8831,UniProt,B4EJP6,GenBank,CAR55410,,,J2315,bcam1554,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13242,PHI:8832,UniProt,B4EKR9,GenBank,CAR55526,,,J2315,bcam1670,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative cyclic-di-GMP signaling protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13243,PHI:8833,UniProt,B4EGX2,GenBank,CAR56115,,,J2315,bcam2256,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative cyclic-di-GMP signaling protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13244,PHI:8834,UniProt,B4EM00,GenBank,CAR56685,,,J2315,bcam2822,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13245,PHI:8835,UniProt,B4EM14,GenBank,CAR56699,,,J2315,bcam2836,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13246,PHI:8836,UniProt,B4ENE7,GenBank,CAR57329,,,J2315,bcas0398,chromosome 3,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13247,PHI:8837,UniProt,B4E944,GenBank,CAR50931,,,J2315,bcal0621,chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative cyclic-di-GMP signaling protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13248,PHI:8838,UniProt,B4ED05,GenBank,CAR51372,,,J2315,cdpA (bcal1069),chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative cyclic-di-GMP signaling protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13249,PHI:8839,UniProt,B4EKM4,GenBank,CAR54438,,,J2315,rpfR (bcam0580),chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative cyclic-di-GMP signaling protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13250,PHI:8840,UniProt,B4EGR5,GenBank,CAR55016,,,J2315,bcam1160,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative cyclic-di-GMP signaling protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13251,PHI:8841,UniProt,B4E974,GenBank,CAR50961,,,J2315,bcal0652,chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate phosphodiesterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13252,PHI:8842,UniProt,B4ED36,GenBank,CAR51403,,,J2315,bcal1100,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate phosphodiesterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13253,PHI:8843,UniProt,B4E9E8,GenBank,CAR53049,,,J2315,bcal2749,chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate phosphodiesterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13254,PHI:8844,UniProt,B4ECX9,GenBank,CAR53511,,,J2315,bcal3188,chromosome 1,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate phosphodiesterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13255,PHI:8845,UniProt,B4EH58,GenBank,CAR54015,,,J2315,bcam0158,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate phosphodiesterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13256,PHI:8846,UniProt,B4EI45,GenBank,CAR56290,,,J2315,bcam2426,chromosome 2,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative diguanylate phosphodiesterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13257,PHI:8847,UniProt,B4EQ30,GenBank,CAR57196,,,J2315,bcas0263,chromosome 3,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"two-component regulatory system, response regulator protein",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13258,PHI:8848,UniProt,B4ENC8,GenBank,CAR57310,,,J2315,bcas0378,chromosome 3,,,,,,95486,Burkholderia cenocepacia,1055524,H111,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,LuxR superfamily regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30687272,PubMed,10.3389/fmicb.2018.03286,Front Microbiol. 2019 Jan 10;9:3286,ttn@sund.ku.dk,Decreased c-di-GMP level mediated by the Bcal2449 protein was required for virulence of B. cenocepacia.,A M Richter 2018,2018,25 genes,Richter-2018-Key Players and Individualists of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13259,PHI:8849,UniProt,Q8Z3Y9,GenBank,AAO70494,,,Ty2,STY3178 (YfdX),,,,,,,28901,Salmonella enterica,90370,subsp. enterica serovar Typhi strain UK-1,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,conserved hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,penicillin G; carbenicillin,penicillin G: CHEBI:18208; carbenicillin: CHEBI:3393,,,,,gene deletion: full; gene complementation,,,YVS,30692978,PubMed,10.3389/fmicb.2018.03329,Front Microbiol. 2019 Jan 14;9:3329,ksj@kribb.re.kr,Oligomeric form but not the monomeric form of st_YfdX was functional and necessary to suppress Salmonella virulence.,H S Lee 2018,2018,1 gene,Lee-2018-Structural and Physiological Explorat,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13260,PHI:8849,UniProt,Q8Z3Y9,GenBank,AAO70494,,,Ty2,STY3178 (YfdX),,"st_YfdX(FFY) - three core residues (Phe42, Phe45 and Tyr165) were substituted with alanine",,,,,28901,Salmonella enterica,90370,subsp. enterica serovar Typhi strain UK-1,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,conserved hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,penicillin G; carbenicillin,penicillin G: CHEBI:18208; carbenicillin: CHEBI:3393,,,,,gene deletion: full; gene complementation,,,YVS,30692978,PubMed,10.3389/fmicb.2018.03329,Front Microbiol. 2019 Jan 14;9:3329,ksj@kribb.re.kr,Oligomeric form but not the monomeric form of st_YfdX was functional and necessary to suppress Salmonella virulence.,H S Lee 2018,2018,1 gene,Lee-2018-Structural and Physiological Explorat,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13261,PHI:8849,UniProt,Q8Z3Y9,GenBank,AAO70494,,,Ty2,STY3178 (YfdX),,st_YfdX(YI) - two hydrophobic residues (Tyr100 and Ile137) were mutated to alanine,,,,,28901,Salmonella enterica,90370,subsp. enterica serovar Typhi strain UK-1,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,penicillin G; carbenicillin,penicillin G: CHEBI:18208; carbenicillin: CHEBI:3393,,,,,gene deletion: full; gene complementation,,,YVS,30692978,PubMed,10.3389/fmicb.2018.03329,Front Microbiol. 2019 Jan 14;9:3329,ksj@kribb.re.kr,Oligomeric form but not the monomeric form of st_YfdX was functional and necessary to suppress Salmonella virulence.,H S Lee 2018,2018,1 gene,Lee-2018-Structural and Physiological Explorat,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13262,PHI:8850,UniProt,C5AG42,GenBank,ACR28799,,,BGR1,prtA (bglu_1g16590),chromosome 1,,,,,,337,Burkholderia glumae,1417989,336gr-1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Trenasse,,,seed,serine metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30694091,PubMed,10.1094/MPMI-11-18-0312-R,Mol Plant Microbe Interact. 2019 Jan 29,jham@agcenter.lsu.edu,PrtA was a major virulence factor among the type II secretion system-dependent extracellular proteins of B. glumae.,T Lelis 2019,2019,2 genes,Lelis-2019-The virulence function and regulati,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13263,PHI:8851,UniProt,Q9LBJ0,GenBank,AAV52806,,,BGR1,toxA,,,,,,,337,Burkholderia glumae,1417989,336gr-1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Trenasse,,,seed,toxoflavin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30694091,PubMed,10.1094/MPMI-11-18-0312-R,Mol Plant Microbe Interact. 2019 Jan 29,jham@agcenter.lsu.edu,PrtA was a major virulence factor among the type II secretion system-dependent extracellular proteins of B. glumae.,T Lelis 2019,2019,2 genes,Lelis-2019-The virulence function and regulati,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13264,PHI:8850,UniProt,C5AG42,GenBank,ACR28799,,,BGR1,prtA (bglu_1g16590),chromosome 1,,,,,PHI:8851,337,Burkholderia glumae,1417989,336gr-1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Trenasse,,,seed,serine metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30694091,PubMed,10.1094/MPMI-11-18-0312-R,Mol Plant Microbe Interact. 2019 Jan 29,jham@agcenter.lsu.edu,PrtA was a major virulence factor among the type II secretion system-dependent extracellular proteins of B. glumae.,T Lelis 2019,2019,2 genes,Lelis-2019-The virulence function and regulati,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13265,PHI:8851,UniProt,Q9LBJ0,GenBank,AAV52806,,,BGR1,toxA,,,,,,PHI:8850,337,Burkholderia glumae,1417989,336gr-1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Trenasse,,,seed,toxoflavin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30694091,PubMed,10.1094/MPMI-11-18-0312-R,Mol Plant Microbe Interact. 2019 Jan 29,jham@agcenter.lsu.edu,PrtA was a major virulence factor among the type II secretion system-dependent extracellular proteins of B. glumae.,T Lelis 2019,2019,2 genes,Lelis-2019-The virulence function and regulati,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13266,PHI:8852,UniProt,Q8PLC3,GenBank,AAM36741,,,306,rpfF,,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,37656,Citrus x paradisi (related: grapefruit),cv. Duncan,,,leaf,putative enoyl-CoA hydratase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30654743,PubMed,10.1186/s12864-018-5384-4,BMC Genomics. 2019 Jan 17;20(1):55,nianwang@ufl.edu,The ΔrpfF mutant produced weaker water soaking phenotypes compared to wild type strain 306.,L Li 2019,2019,1 gene,Li-2019-Diffusible signal factor (DSF)-mediate,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13267,PHI:8853,UniProt,A0A386NHW9,GenBank,AYE22913,,,QJ-2D-Sal,SseL,,,,,,,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),Hy-line white,,,,effector protein,,,NF-κB pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30703474,PubMed,10.1016/j.micpath.2019.01.035,Microb Pathog. 2019 Jan 29;129:1-6,jiao@yzu.edu.cn,"SseL significantly enhanced the virulence of Salmonella Pullorum in chickens and suppressed activation of the cellular NF-κB pathway, thus inhibiting cellular inflammatory cytokine expression.",S Geng 2019,2019,1 gene,Geng-2019-The SseL protein inhibits the intrac,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13268,PHI:8853,UniProt,A0A386NHW9,GenBank,AYE22913,,,QJ-2D-Sal,SseL,,,,,,,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,effector protein,,,NF-κB pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30703474,PubMed,10.1016/j.micpath.2019.01.035,Microb Pathog. 2019 Jan 29;129:1-6,jiao@yzu.edu.cn,The sseL mutant exhibited a decreased replication ability and an inhibitory effect on inflammatory cytokines in HD11 cells.,S Geng 2019,2019,1 gene,Geng-2019-The SseL protein inhibits the intrac,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13269,PHI:8854,UniProt,B8NTM0,GenBank,EED46287,,,NRRL3357,AFLA_099500 (sakA),,,,,,,5059,Aspergillus flavus,,,aspergillosis,monocots,4577,Zea mays (related: maize),,,,kernel,mitogen-activated protein kinase,,,aflatoxin biosynthesis,increased virulence (hypervirulence),,,,,,reduced; aberrant,increased,,,no,NaCl; D-sorbitol; SDS; Congo red,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30646608,PubMed,10.3390/toxins11010041,Toxins (Basel). 2019 Jan 14;11(1). pii: E41,yjmail2008@fafu.edu.cn,The virulence assay on both maize kernel and peanut seeds showed that ΔAfsakA strain drastically produced more conidia and Aflatoxin B1 than wild-type and complementary strains.,E Tumukunde 2019,2019,1 gene,Tumukunde-2019-Osmotic-Adaptation Response of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13270,PHI:8854,UniProt,B8NTM0,GenBank,EED46287,,,NRRL3357,AFLA_099500 (sakA),,,,,,,5059,Aspergillus flavus,,,aspergillosis,eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,mitogen-activated protein kinase,,,aflatoxin biosynthesis,increased virulence (hypervirulence),,,,,,reduced; aberrant,increased,,,no,NaCl; D-sorbitol; SDS; Congo red,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30646608,PubMed,10.3390/toxins11010041,Toxins (Basel). 2019 Jan 14;11(1). pii: E41,yjmail2008@fafu.edu.cn,The virulence assay on both maize kernel and peanut seeds showed that ΔAfsakA strain drastically produced more conidia and Aflatoxin B1 than wild-type and complementary strains.,E Tumukunde 2019,2019,1 gene,Tumukunde-2019-Osmotic-Adaptation Response of,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13271,PHI:8855,UniProt,Q4UUK7,GenBank,AAY49266,,,8004,lolA,,,,,,,339,Xanthomonas campestris,340,pv. campestris strain Xc17,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Capitata,,,leaf,outer-membrane lipoprotein carrier protein,,,,reduced virulence,,,,,,,,wild type,,no,SDS; EDTA; polymyxin B,SDS: CHEBI:8984; EDTA: CHEBI:64758; polymyxin B: CHEBI:8309,,,,,gene deletion: full; gene complementation,,,YVS,30665348,PubMed,10.1186/s12866-019-1387-9,BMC Microbiol. 2019 Jan 21;19(1):20,ymhsiao@ctust.edu.tw,"The lolA mutant exhibited significant reductions in bacterial attachment, extracellular enzyme production, virulence, and tolerance in the presence of myriad membrane-perturbing agents.",C T Liao 2019,2019,1 gene,Liao-2019-Functional characterization and prot,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13272,PHI:8856,UniProt,A0A2I7YRH9,GenBank,AUS82351,,,WT178,CgAzf1 (KY581593),,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,C2H2 zinc-finger protein transcription factor,,,melanin biosynthesis pathway,reduced virulence,,yes,,,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30725325,PubMed,10.1007/s10482-019-01243-1,Antonie Van Leeuwenhoek. 2019 Feb 6,liuzhiqiang80@126.com,Deletion of CgAzf1 resulted in decreased melanin production and hydrophilicity of aerial mycelium was increased.,X Li 2019,2019,1 gene,Li-2019-Transcription factor CgAzf1 regulates,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13273,PHI:8856,UniProt,A0A2I7YRH9,GenBank,AUS82351,,,WT178,CgAzf1 (KY581593),,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,C2H2 zinc-finger protein transcription factor,,,melanin biosynthesis pathway,reduced virulence,,yes,,,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30725325,PubMed,10.1007/s10482-019-01243-1,Antonie Van Leeuwenhoek. 2019 Feb 6,liuzhiqiang80@126.com,Deletion of CgAzf1 resulted in decreased melanin production and hydrophilicity of aerial mycelium was increased.,X Li 2019,2019,1 gene,Li-2019-Transcription factor CgAzf1 regulates,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13274,PHI:8857,UniProt,D5LHI2,GenBank,ADE34180,,,89 A2 2-3,slnCl1 (GU907087),,,,,,,290576,Colletotrichum lindemuthianum,,89 A2 2-3,anthracnose,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Rosinha,,,leaf,histidine kinase class IV,,,,reduced virulence,,yes,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,30642461,PubMed,10.1016/j.micres.2018.10.005,Microbiol Res. 2019 Feb;219:110-122,mvqueiro@ufv.br,SlnCl1-silenced strain was deficient on melanin production and showed a delayed production of non-melanized apressoria compared to wild-type C. lindemuthianum.,G B Nogueira 2019,2019,1 gene,Bicalho Nogueir-2019-The histidine kinase slnC,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13275,PHI:8858,UniProt,G2XD68,GenBank,EGY16936,,,VdLs.17,VdSSEP1 (VDAG-08100),chromosome 6,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. R15,,,leaf,serin endopeptidase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30651348,PubMed,10.1105/tpc.18.00390,Plant Cell. 2019 Jan 16. pii: tpc.00390.2018,xiagx@im.ac.cn,Host gene alteration data available for chitinase 28 (Chi28) and cysteine-rich repeat protein 1 (CRR1). Knockout of VdSSEP1 in V. dahliae destroyed the pathogenicity of this fungus.,L B Han 2019,2019,1 gene,Han-2019-The Cotton Apoplastic Protein CRR1 St,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13276,PHI:8859,UniProt,Q4WDW4,GenBank,EAL86213,,,Af293,RgsD (Afu5g00900),chromosome 5,,,GpaB; GanA; GpaA,UniProt: Q8TFX6; GenBank: CAC81805; UniProt: Q4WYB0; GenBank: EAL92343; UniProt: Q8J132; Gen,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative G-protein signalling regulator,,,PKA signaling pathway,increased virulence (hypervirulence),,,,,,increased,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,30692551,PubMed,10.1038/s41598-018-37124-2,Sci Rep. 2019 Jan 28;9(1):811,jyu1@wisc.edu,The ΔrgsD mutant displayed increased gliotoxin production and elevated virulence towards Galleria mellonella wax moth larvae.,Y Kim 2019,2019,1 gene,Kim-2019-RgsD negatively controls development,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13277,PHI:8860,UniProt,B5F1X4,GenBank,ACH49260,,,SL483,SopB,,,,,,PHI:8861,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung; intestine; kidney,inositol phosphate phosphatase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30671294,PubMed,10.7717/peerj.5989,PeerJ. 2019 Jan 16;7:e5989,ykcheah@upm.edu.my,"The survival rate for wild-type (WT) infected mice is 33.33%, 83.33% for BD, 50% for LD and 83.33% for BDLA.",C P Gwee 2019,2019,4 genes,Gwee-2019-Targeted inactivation of Salmonella,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13278,PHI:8861,UniProt,A0A2T9I433,GenBank,RKD14147,,,400100 5-3,SopD,,,,,,PHI:8860,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung; intestine; kidney,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30671294,PubMed,10.7717/peerj.5989,PeerJ. 2019 Jan 16;7:e5989,ykcheah@upm.edu.my,"The survival rate for wild-type (WT) infected mice is 33.33%, 83.33% for BD, 50% for LD and 83.33% for BDLA.",C P Gwee 2019,2019,4 genes,Gwee-2019-Targeted inactivation of Salmonella,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13279,PHI:8862,UniProt,B5F7U8,GenBank,ACH50288,,,SL483,LeuB,,,,,,PHI:8863,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung; intestine; kidney,3-isopropylmalate dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30671294,PubMed,10.7717/peerj.5989,PeerJ. 2019 Jan 16;7:e5989,ykcheah@upm.edu.my,"The survival rate for wild-type (WT) infected mice is 33.33%, 83.33% for BD, 50% for LD and 83.33% for BDLA.",C P Gwee 2019,2019,4 genes,Gwee-2019-Targeted inactivation of Salmonella,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13280,PHI:8863,UniProt,B5F8I0,GenBank,ACH49836,,,SL483,ArgD,,,,,,PHI:8862,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung; intestine; kidney,acetylornithine/succinyldiaminopimelate aminotransferase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30671294,PubMed,10.7717/peerj.5989,PeerJ. 2019 Jan 16;7:e5989,ykcheah@upm.edu.my,"The survival rate for wild-type (WT) infected mice is 33.33%, 83.33% for BD, 50% for LD and 83.33% for BDLA.",C P Gwee 2019,2019,4 genes,Gwee-2019-Targeted inactivation of Salmonella,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13281,PHI:8860,UniProt,B5F1X4,GenBank,ACH49260,,,SL483,SopB,,,,,,PHI:8861; PHI:8862; PHI:8863,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung; intestine; kidney,SPI-1 type III secretion system effector inositol phosphate phosphatase SopB,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30671294,PubMed,10.7717/peerj.5989,PeerJ. 2019 Jan 16;7:e5989,ykcheah@upm.edu.my,"The survival rate for wild-type (WT) infected mice is 33.33%, 83.33% for BD, 50% for LD and 83.33% for BDLA.",C P Gwee 2019,2019,4 genes,Gwee-2019-Targeted inactivation of Salmonella,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13282,PHI:8861,UniProt,A0A2T9I433,GenBank,RKD14147,,,400100 5-3,SopD,,,,,,PHI:8860; PHI:8862; PHI:8863,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung; intestine; kidney,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30671294,PubMed,10.7717/peerj.5989,PeerJ. 2019 Jan 16;7:e5989,ykcheah@upm.edu.my,"The survival rate for wild-type (WT) infected mice is 33.33%, 83.33% for BD, 50% for LD and 83.33% for BDLA.",C P Gwee 2019,2019,4 genes,Gwee-2019-Targeted inactivation of Salmonella,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13283,PHI:8862,UniProt,B5F7U8,GenBank,ACH50288,,,SL483,LeuB,,,,,,PHI:8860; PHI:8861; PHI:8863,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung; intestine; kidney,3-isopropylmalate dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30671294,PubMed,10.7717/peerj.5989,PeerJ. 2019 Jan 16;7:e5989,ykcheah@upm.edu.my,"The survival rate for wild-type (WT) infected mice is 33.33%, 83.33% for BD, 50% for LD and 83.33% for BDLA.",C P Gwee 2019,2019,4 genes,Gwee-2019-Targeted inactivation of Salmonella,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13284,PHI:8863,UniProt,B5F8I0,GenBank,ACH49836,,,SL483,ArgD,,,,,,PHI:8860; PHI:8861; PHI:8862,28901,Salmonella enterica,58095,subsp. enterica serovar Agona strain Ag 1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung; intestine; kidney,acetylornithine/succinyldiaminopimelate aminotransferase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30671294,PubMed,10.7717/peerj.5989,PeerJ. 2019 Jan 16;7:e5989,ykcheah@upm.edu.my,"The survival rate for wild-type (WT) infected mice is 33.33%, 83.33% for BD, 50% for LD and 83.33% for BDLA.",C P Gwee 2019,2019,4 genes,Gwee-2019-Targeted inactivation of Salmonella,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13285,PHI:8864,UniProt,Q5GA16,GenBank,AAW32456,,,,WipA,,D180A,,,,,446,Legionella pneumophila,1080311,Lp02,Legionnaires' disease,primates,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression; gene complementation,,,YVS,30702192,PubMed,10.1111/cmi.13014,Cell Microbiol. 2019 Jan 31:e13014,luyj@mail.sysu.edu.cn,"The wipA/legK2 double mutant manifested ~4 fold growth defect compared to the wild-type, ΔwipA or ΔlegK2 mutant strain in macrophages, indicating that WipA and LegK2 was required for optimal intracellular replication of L. pneumophila.",L He 2019,2019,2 genes,He-2019-The Legionella pneumophila Effector Wi,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13286,PHI:8865,UniProt,Q5ZTM4,GenBank,AAU28203,,,Philadelphia 1,legK2,,,,,,,446,Legionella pneumophila,1080311,Lp02,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30702192,PubMed,10.1111/cmi.13014,Cell Microbiol. 2019 Jan 31:e13014,luyj@mail.sysu.edu.cn,"The wipA/legK2 double mutant manifested ~4 fold growth defect compared to the wild-type, ΔwipA or ΔlegK2 mutant strain in macrophages, indicating that WipA and LegK2 was required for optimal intracellular replication of L. pneumophila.",L He 2019,2019,2 genes,He-2019-The Legionella pneumophila Effector Wi,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13287,PHI:8864,UniProt,Q5GA16,GenBank,AAW32456,,,,WipA,,,,,,PHI:8865,446,Legionella pneumophila,1080311,Lp02,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30702192,PubMed,10.1111/cmi.13014,Cell Microbiol. 2019 Jan 31:e13014,luyj@mail.sysu.edu.cn,"The wipA/legK2 double mutant manifested ~4 fold growth defect compared to the wild-type, ΔwipA or ΔlegK2 mutant strain in macrophages, indicating that WipA and LegK2 was required for optimal intracellular replication of L. pneumophila.",L He 2019,2019,2 genes,He-2019-The Legionella pneumophila Effector Wi,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13288,PHI:8865,UniProt,Q5ZTM4,GenBank,AAU28203,,,Philadelphia 1,legK2,,,,,,PHI:8864,446,Legionella pneumophila,1080311,Lp02,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30702192,PubMed,10.1111/cmi.13014,Cell Microbiol. 2019 Jan 31:e13014,luyj@mail.sysu.edu.cn,"The wipA/legK2 double mutant manifested ~4 fold growth defect compared to the wild-type, ΔwipA or ΔlegK2 mutant strain in macrophages, indicating that WipA and LegK2 was required for optimal intracellular replication of L. pneumophila.",L He 2019,2019,2 genes,He-2019-The Legionella pneumophila Effector Wi,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13289,PHI:8866,UniProt,Q5AJ65,GenBank,AOW28170,,,SC5314,Pmc1,chromosome 3,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,calcium-transporting P-type ATPase,,,,reduced virulence,,,,,,,,reduced,,no,LiCl; CdSO4; SDS; CaCl2; fluconazole; amorolfine; EGTA,LiCl: CHEBI:48607; CdSO4: CHEBI:50292; SDS: CHEBI:8984; CaCl2: CHEBI:3312; fluconazole: CHEBI:46081; amorolfine: CHEBI:599440; EGTA: CHEBI:30740,,,,,gene deletion: full; gene complementation,,,YVS,30728284,PubMed,10.1128/mSphere.00715-18,mSphere. 2019 Feb 6;4(1). pii: e00715-18,gpalmer5@uthsc.edu,"Pmc1p, but not Vcx1p, was required for C. albicans pathogenicity following dissemination through the bloodstream.",A Luna-Tapia 2019,2019,2 genes,Luna-Tapia-2019-The Vacuolar Ca(2+) ATPase Pum,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13290,PHI:8867,UniProt,Q59QB4,GenBank,AOW26496,,,SC5314,vcx1,chromosome 1,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,H+/Ca2+ exchanger,,,,unaffected pathogenicity,,,,,,,,wild type,,no,LiCl; CdSO4; SDS; CaCl2; fluconazole; amorolfine; EGTA,LiCl: CHEBI:48607; CdSO4: CHEBI:50292; SDS: CHEBI:8984; CaCl2: CHEBI:3312; fluconazole: CHEBI:46081; amorolfine: CHEBI:599440; EGTA: CHEBI:30740,,,,,gene deletion: full; gene complementation,,,YVS,30728284,PubMed,10.1128/mSphere.00715-18,mSphere. 2019 Feb 6;4(1). pii: e00715-18,gpalmer5@uthsc.edu,"Pmc1p, but not Vcx1p, was required for C. albicans pathogenicity following dissemination through the bloodstream.",A Luna-Tapia 2019,2019,2 genes,Luna-Tapia-2019-The Vacuolar Ca(2+) ATPase Pum,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13291,PHI:8868,UniProt,X5FDX7,GenBank,AUG94584,,,MS8345,vgrG1,,,,,,PHI:8869,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),,,,brain microvascular endothelial cell line,actin cross-linking toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13292,PHI:8869,,no data found,,,,,,PCN033_0248,,,,,,PHI:8868,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),,,,brain microvascular endothelial cell line,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13293,PHI:8870,UniProt,A0A0G3K3W0,GenBank,AKK48148,,,PCN033,vgrG2,,,,,,PHI:8871,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),,,,brain microvascular endothelial cell line,type VI secretion system Vgr family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13294,PHI:8871,,no data found,,,,,,PCN033_1588,,,,,,PHI:8870,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),,,,brain microvascular endothelial cell line,type VI secretion system Vgr family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13295,PHI:8868,UniProt,X5FDX7,GenBank,AUG94584,,,MS8345,vgrG1,,,,,,PHI:8869; PHI:8870; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),,,,brain microvascular endothelial cell line,actin cross-linking toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13296,PHI:8869,,no data found,,,,,,PCN033_0248,,,,,,PHI:8868; PHI:8870; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),,,,brain microvascular endothelial cell line,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13297,PHI:8870,UniProt,A0A0G3K3W0,GenBank,AKK48148,,,PCN033,vgrG2,,,,,,PHI:8868; PHI:8869; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),,,,brain microvascular endothelial cell line,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13298,PHI:8871,,no data found,,,,,,PCN033_1588,,,,,,PHI:8868; PHI:8869; PHI:8870,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),,,,brain microvascular endothelial cell line,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13299,PHI:8868,UniProt,X5FDX7,GenBank,AUG94584,,,MS8345,vgrG1,,,,,,PHI:8869,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,actin cross-linking toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13300,PHI:8869,,no data found,,,,,,PCN033_0248,,,,,,PHI:8868,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13301,PHI:8870,UniProt,A0A0G3K3W0,GenBank,AKK48148,,,PCN033,vgrG2,,,,,,PHI:8871,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13302,PHI:8871,,no data found,,,,,,PCN033_1588,,,,,,PHI:8870,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13303,PHI:8868,UniProt,X5FDX7,GenBank,AUG94584,,,MS8345,vgrG1,,,,,,PHI:8869; PHI:8870; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,actin cross-linking toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13304,PHI:8869,,no data found,,,,,,PCN033_0248,,,,,,PHI:8868; PHI:8870; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13305,PHI:8870,UniProt,A0A0G3K3W0,GenBank,AKK48148,,,PCN033,vgrG2,,,,,,PHI:8868; PHI:8869; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13306,PHI:8871,,no data found,,,,,,PCN033_1588,,,,,,PHI:8868; PHI:8869; PHI:8870,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13307,PHI:8868,UniProt,X5FDX7,GenBank,AUG94584,,,MS8345,vgrG1,,,,,,PHI:8870; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,actin cross-linking toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13308,PHI:8870,UniProt,A0A0G3K3W0,GenBank,AKK48148,,,PCN033,vgrG2,,,,,,PHI:8868; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13309,PHI:8871,,no data found,,,,,,PCN033_1588,,,,,,PHI:8868; PHI:8870,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13310,PHI:8869,,no data found,,,,,,PCN033_0248,,,,,,PHI:8870; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13311,PHI:8870,UniProt,A0A0G3K3W0,GenBank,AKK48148,,,PCN033,vgrG2,,,,,,PHI:8869; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13312,PHI:8871,,no data found,,,,,,PCN033_1588,,,,,,PHI:8869; PHI:8870,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,type VI secretion system Vgr family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13313,PHI:8868,UniProt,X5FDX7,GenBank,AUG94584,,,MS8345,vgrG1,,,,,,PHI:8869,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,actin cross-linking toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13314,PHI:8869,,no data found,,,,,,PCN033_0248,,,,,,PHI:8868,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13315,PHI:8868,UniProt,X5FDX7,GenBank,AUG94584,,,MS8345,vgrG1,,,,,,PHI:8869; PHI:8870; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,actin cross-linking toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13316,PHI:8869,,no data found,,,,,,PCN033_0248,,,,,,PHI:8868; PHI:8870; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13317,PHI:8870,UniProt,A0A0G3K3W0,GenBank,AKK48148,,,PCN033,vgrG2,,,,,,PHI:8868; PHI:8869; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13318,PHI:8871,,no data found,,,,,,PCN033_1588,,,,,,PHI:8868; PHI:8869; PHI:8870,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,type VI secretion system Vgr family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13319,PHI:8869,,no data found,,,,,,PCN033_0248,,,,,,PHI:8870; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,type VI secretion system Vgr family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13320,PHI:8870,UniProt,A0A0G3K3W0,GenBank,AKK48148,,,PCN033,vgrG2,,,,,,PHI:8869; PHI:8871,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,type VI secretion system Vgr family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13321,PHI:8871,,no data found,,,,,,PCN033_1588,,,,,,PHI:8869; PHI:8870,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,type VI secretion system Vgr family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30676217,PubMed,10.1080/21505594.2019.1573491,Virulence. 2019 Dec;10(1):118-132,tanchen@mail.hzau.edu.cn,"Deletion of vgrG1 significantly led to the decrease in the multiplication capacity of PCN033, however, the deletion of 0248 and/or the deletion of vgrG2 and 1588 had no effect on the pathogenicity of PCN033.",B Zong 2019,2019,4 genes,Zong-2019-Characterization of multiple type-VI,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13322,PHI:8872,,no data found,GenBank,ABO10774,,,ATCC 17978,LpxO,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,blood,aspartyl beta-hydroxylase,,,,reduced virulence,,,,,,,,wild type,,no,polymyxin B; colistin,polymyxin B: CHEBI:8309; colistin: CHEBI:37943,,,,,gene mutation; gene complementation,,,YVS,30745327,PubMed,10.1128/IAI.00066-19,Infect Immun. 2019 Feb 11. pii: IAI.00066-19,j.bengoechea@qub.ac.uk,The decreased survival of the lpxO mutant in whole human blood was associated with the lack of 2-hydroxylation in the lipid A.,T L Bartholomew 2019,2019,1 gene,Bartholomew-2019-2-hydroxylation of Acinetobac,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13323,PHI:8872,,no data found,GenBank,ABO10774,,,ATCC 17978,LpxO,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,aspartyl beta-hydroxylase,,,,reduced virulence,,,,,,,,wild type,,no,polymyxin B; colistin,polymyxin B: CHEBI:8309; colistin: CHEBI:37943,,,,,gene mutation; gene complementation,,,YVS,30745327,PubMed,10.1128/IAI.00066-19,Infect Immun. 2019 Feb 11. pii: IAI.00066-19,j.bengoechea@qub.ac.uk,LpxO-mediated 2-hydroxylation of A. baumannii lipid A was necessary for the virulence of this pathogen in G. mellonella by limiting the production of antimicrobial peptides and promoting resistance to them.,T L Bartholomew 2019,2019,1 gene,Bartholomew-2019-2-hydroxylation of Acinetobac,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13324,PHI:8872,,no data found,GenBank,ABO10774,,,ATCC 17978,LpxO,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BoMaMa-J2imm cell line,,,bone marrow-derived macrophage,aspartyl beta-hydroxylase,,,,reduced virulence,,,,,,,,wild type,,no,polymyxin B; colistin,polymyxin B: CHEBI:8309; colistin: CHEBI:37943,,,,,gene mutation; gene complementation,,,YVS,30745327,PubMed,10.1128/IAI.00066-19,Infect Immun. 2019 Feb 11. pii: IAI.00066-19,j.bengoechea@qub.ac.uk,The heightened inflammation induced by the lpxO mutant was due to the lack of 2-hydroxylation in the lipid A.,T L Bartholomew 2019,2019,1 gene,Bartholomew-2019-2-hydroxylation of Acinetobac,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13325,PHI:8873,UniProt,Q8X696,GenBank,AF461166_1,,,C984; ATCC 43890,Stx1a,,,,,,,562,Escherichia coli,,TW08571,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,Shiga toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,30670557,PubMed,10.1128/IAI.00787-18,Infect Immun. 2019 Jan 22. pii: IAI.00787-18,angela.melton-celsa@usuhs.edu,Stx1a reduced both the pathogenicity of Stx2 in vivo and cytotoxicity in vitro.,C D Petro 2019,2019,2 genes,Petro-2019-Shiga toxin (Stx) type 1a reduces t,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13326,PHI:8874,UniProt,Q8XBV2,GenBank,AF175707_1,,,O157 KNIH317,Stx2a,,,,,,,562,Escherichia coli,,TW08571,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,Shiga toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,30670557,PubMed,10.1128/IAI.00787-18,Infect Immun. 2019 Jan 22. pii: IAI.00787-18,angela.melton-celsa@usuhs.edu,Stx1a reduced both the pathogenicity of Stx2 in vivo and cytotoxicity in vitro.,C D Petro 2019,2019,2 genes,Petro-2019-Shiga toxin (Stx) type 1a reduces t,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13327,PHI:8873,UniProt,Q8X696,GenBank,AF461166_1,,,C984; ATCC 43890,Stx1a,,,,,,,562,Escherichia coli,,TW08571,infection,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,,Shiga toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,30670557,PubMed,10.1128/IAI.00787-18,Infect Immun. 2019 Jan 22. pii: IAI.00787-18,angela.melton-celsa@usuhs.edu,Stx1a reduced both the pathogenicity of Stx2 in vivo and cytotoxicity in vitro.,C D Petro 2019,2019,2 genes,Petro-2019-Shiga toxin (Stx) type 1a reduces t,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13328,PHI:8874,UniProt,Q8XBV2,GenBank,AF175707_1,,,O157 KNIH317,Stx2a,,,,,,,562,Escherichia coli,,TW08571,infection,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,,Shiga toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,30670557,PubMed,10.1128/IAI.00787-18,Infect Immun. 2019 Jan 22. pii: IAI.00787-18,angela.melton-celsa@usuhs.edu,Stx1a reduced both the pathogenicity of Stx2 in vivo and cytotoxicity in vitro.,C D Petro 2019,2019,2 genes,Petro-2019-Shiga toxin (Stx) type 1a reduces t,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13329,PHI:8875,UniProt,Q4WZP3,GenBank,EAL93922,,,Af293,gefA (Afu2g16240),chromosome 2,,,,,,746128,Aspergillus fumigatus,,ku80 ΔpyrG,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,cell division control protein,,,,unaffected pathogenicity,,,,,,,,reduced,reduced,no,calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; H2O2; caspofungin; voriconazole; nikkomycin Z,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full; gene complementation,,,YVS,30698898,PubMed,10.1111/cmi.13013,Cell Microbiol. 2019 Jan 30:e13013,jfortwen@uthsc.edu,"RasGEF single deletion mutants displayed no statistically significant change in 15-day survival rates, however, the ΔgefA/pTetOn-gefB double mutant displayed complete avirulence in mice models.",A Martin-Vicente 2019,2019,3 genes,Martin-Vicente-2019-SH3-class Ras Guanine Nucl,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13330,PHI:8876,UniProt,Q4WNQ3,GenBank,EAL90131,,,Af293,gefB (Afu4g06570),chromosome 4,,,,,,746128,Aspergillus fumigatus,,ku80 ΔpyrG,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,"Ras guanine-nucleotide exchange protein, putative",,,,unaffected pathogenicity,,,,,,,,reduced,increased,no,calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; H2O2; caspofungin; voriconazole; nikkomycin Z,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full; gene complementation,,,YVS,30698898,PubMed,10.1111/cmi.13013,Cell Microbiol. 2019 Jan 30:e13013,jfortwen@uthsc.edu,"RasGEF single deletion mutants displayed no statistically significant change in 15-day survival rates, however, the ΔgefA/pTetOn-gefB double mutant displayed complete avirulence in mice models.",A Martin-Vicente 2019,2019,3 genes,Martin-Vicente-2019-SH3-class Ras Guanine Nucl,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13331,PHI:8877,UniProt,Q4WJV1,GenBank,EAL88181,,,Af293,gefC (Afu1g04700),chromosome 1,,,,,,746128,Aspergillus fumigatus,,ku80 ΔpyrG,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,"Ras guanyl-nucleotide exchange factor RasGEF, putative",,,,unaffected pathogenicity,,,,,,,,reduced,reduced,no,calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; H2O2; caspofungin; voriconazole; nikkomycin Z,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full; gene complementation,,,YVS,30698898,PubMed,10.1111/cmi.13013,Cell Microbiol. 2019 Jan 30:e13013,jfortwen@uthsc.edu,"RasGEF single deletion mutants displayed no statistically significant change in 15-day survival rates, however, the ΔgefA/pTetOn-gefB double mutant displayed complete avirulence in mice models.",A Martin-Vicente 2019,2019,3 genes,Martin-Vicente-2019-SH3-class Ras Guanine Nucl,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13332,PHI:8875,UniProt,Q4WZP3,GenBank,EAL93922,,,Af293,gefA (Afu2g16240),chromosome 2,ΔgefA/pTetOn-gefB,,,,PHI:8876,746128,Aspergillus fumigatus,,ku80 ΔpyrG,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,cell division control protein,,,,loss of pathogenicity,,,,,,aberrant,,reduced,,no,calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; H2O2; caspofungin; voriconazole; nikkomycin Z,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; nikkomycin Z: CHEBI:623918,,,,,promoter mutation,,,YVS,30698898,PubMed,10.1111/cmi.13013,Cell Microbiol. 2019 Jan 30:e13013,jfortwen@uthsc.edu,"RasGEF single deletion mutants displayed no statistically significant change in 15-day survival rates, however, the ΔgefA/pTetOn-gefB double mutant displayed complete avirulence in mice models.",A Martin-Vicente 2019,2019,3 genes,Martin-Vicente-2019-SH3-class Ras Guanine Nucl,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13333,PHI:8876,UniProt,Q4WNQ3,GenBank,EAL90131,,,Af293,gefB (Afu4g06570),chromosome 4,ΔgefA/pTetOn-gefB,,,,PHI:8875,746128,Aspergillus fumigatus,,ku80 ΔpyrG,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,"Ras guanine-nucleotide exchange protein, putative",,,,loss of pathogenicity,,,,,,aberrant,,reduced,,no,calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; H2O2; caspofungin; voriconazole; nikkomycin Z,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; nikkomycin Z: CHEBI:623918,,,,,promoter mutation,,,YVS,30698898,PubMed,10.1111/cmi.13013,Cell Microbiol. 2019 Jan 30:e13013,jfortwen@uthsc.edu,"RasGEF single deletion mutants displayed no statistically significant change in 15-day survival rates, however, the ΔgefA/pTetOn-gefB double mutant displayed complete avirulence in mice models.",A Martin-Vicente 2019,2019,3 genes,Martin-Vicente-2019-SH3-class Ras Guanine Nucl,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13334,PHI:8878,UniProt,H1VQ06,GenBank,CCF42312,,,IMI 349063,ChBUB2 (XP_018164413),,,,,,,80884,Colletotrichum higginsianum,,337-5,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,TBC domain-containing protein,,,MEN/SIN pathway,reduced virulence,,yes,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30715740,PubMed,10.1111/nph.15728,New Phytol. 2019 Feb 4,y_kubo@kpu.ac.jp,"In bub2 mutants of both fungi, C. higginsianum and M. oryzae, S phase initiation was earlier, and septum formation coordinated with a septation initiation network protein and contractile actin ring was impaired.",F Fukuda 2019,2019,3 genes,Fukada-2019-Plant pathogenic fungi Colletotric,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13335,PHI:8879,UniProt,G4MRC5,GenBank,EHA58250,,,70-15,MoBUB2 (XP_003710862),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Hoku-1,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Nakaizumi-zairai,,,leaf,mitotic check point protein,,,MEN/SIN pathway,reduced virulence,,yes,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30715740,PubMed,10.1111/nph.15728,New Phytol. 2019 Feb 4,y_kubo@kpu.ac.jp,"In bub2 mutants of both fungi, C. higginsianum and M. oryzae, S phase initiation was earlier, and septum formation coordinated with a septation initiation network protein and contractile actin ring was impaired.",F Fukuda 2019,2019,3 genes,Fukada-2019-Plant pathogenic fungi Colletotric,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13336,PHI:8880,UniProt,N4VRT7,GenBank,EHA58250,,,MAFF 240422,CoBUB2 (ENH83696),,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,two-component GTPase activating protein (GAP) complex,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30715740,PubMed,10.1111/nph.15728,New Phytol. 2019 Feb 4,y_kubo@kpu.ac.jp,Infection of cobub2Δ resulted in enhanced callose and ROS accumulation.,F Fukuda 2019,2019,3 genes,Fukada-2019-Plant pathogenic fungi Colletotric,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13337,PHI:8881,UniProt,A9CL19,GenBank,AAK90947,,,C58,VirD5,,,,,,,358,Agrobacterium tumefaciens,,C58,crown gall,basidiomycetes,5537,Rhodotorula mucilaginosa (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host,,,YVS,30667529,PubMed,10.1111/nph.15700,New Phytol. 2019 Jan 22,P.J.J.Hooykaas@biology.leidenuniv.nl,Enhanced activity of conserved kinase VirD5 delayed mitotic progression and caused chromosome missegregation and aneuploidy.,X Zhang 2019,2019,1 gene,Zhang-2019-The Agrobacterium VirD5 protein hyp,BATCH_090B,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13338,PHI:8882,UniProt,E0WK31,GenBank,CBV36702,,,v225,cagY,,,,,,,210,Helicobacter pylori,,7.13,gastric infection,rodents,10047,Meriones unguiculatus (related: Mongolian gerbil),,,,gastric epithelial cell,"outer membrane protein, T4SS needle core complex component",,,,reduced virulence,,,,,,,,,,no,α-difluoromethylornithine,α-difluoromethylornithine: CHEBI:41948,,,,,gene deletion: full; gene complementation,,,YVS,30804204,PubMed,10.1073/pnas.1814497116,Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5077-5085,keith.wilson@vumc.org,H. pylori output strains isolated from gerbils treated with DFMO exhibited reduced ability to translocate CagA in gastric epithelial cells.,J C Sierra 2019,2019,1 gene,Sierra-2019-alpha-Difluoromethylornithine redu,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13339,PHI:8883,UniProt,A7EKQ2,GenBank,EDO03418,,,1980,SsTrr1 (SS1G_05899),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,thioredoxin reductase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; auranofin,H2O2: CHEBI:16240; auranofin: CHEBI:2922,,,,,altered gene expression / gene regulation: silencing,,,YVS,30837967,PubMed,10.3389/fmicb.2019.00233,Front Microbiol. 2019 Feb 14;10:233,zbyuyang@swu.edu.cn,SsTrr1 gene-silenced strains produced a smaller number of larger sclerotia on potato dextrose agar medium.,J Zhang 2019,2019,1 gene,Zhang-2019-Sclerotinia sclerotiorum Thioredoxi,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13340,PHI:8883,UniProt,A7EKQ2,GenBank,EDO03418,,,1980,SsTrr1 (SS1G_05899),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,thioredoxin reductase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; auranofin,H2O2: CHEBI:16240; auranofin: CHEBI:2922,,,,,altered gene expression / gene regulation: silencing,,,YVS,30837967,PubMed,10.3389/fmicb.2019.00233,Front Microbiol. 2019 Feb 14;10:233,zbyuyang@swu.edu.cn,SsTrr1 gene-silenced strains produced a smaller number of larger sclerotia on potato dextrose agar medium.,J Zhang 2019,2019,1 gene,Zhang-2019-Sclerotinia sclerotiorum Thioredoxi,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13341,PHI:8884,UniProt,Q8XW15,GenBank,CAD16367,,,GMI1000,aroG1,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,phospho-2-dehydro-3-deoxyheptonate aldolase,,,shikimate pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30809210,PubMed,10.3389/fmicb.2019.00183,Front Microbiol. 2019 Feb 12;10:183,bioyongzhang@swu.edu.cn,"Virulence of the aroG1/2 or aroG1 mutants was completely diminished or significantly impaired in tomato and tobacco plants, but not the aroG2 mutants.",W Zhang 2019,2019,2 genes,Zhang-2019-Functional Characterization of Two,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13342,PHI:8885,UniProt,Q8Y1E7,GenBank,CAD14273,,,GMI1000,aroG2,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,phospho-2-dehydro-3-deoxyheptonate aldolase,,,shikimate pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30809210,PubMed,10.3389/fmicb.2019.00183,Front Microbiol. 2019 Feb 12;10:183,bioyongzhang@swu.edu.cn,"Virulence of the aroG1/2 or aroG1 mutants was completely diminished or significantly impaired in tomato and tobacco plants, but not the aroG2 mutants.",W Zhang 2019,2019,2 genes,Zhang-2019-Functional Characterization of Two,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13343,PHI:8884,UniProt,Q8XW15,GenBank,CAD16367,,,GMI1000,aroG1,,,,,,PHI:8885,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,phospho-2-dehydro-3-deoxyheptonate aldolase,,,shikimate pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30809210,PubMed,10.3389/fmicb.2019.00183,Front Microbiol. 2019 Feb 12;10:183,bioyongzhang@swu.edu.cn,"Virulence of the aroG1/2 or aroG1 mutants was completely diminished or significantly impaired in tomato and tobacco plants, but not the aroG2 mutants.",W Zhang 2019,2019,2 genes,Zhang-2019-Functional Characterization of Two,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13344,PHI:8885,UniProt,Q8Y1E7,GenBank,CAD14273,,,GMI1000,aroG2,,,,,,PHI:8884,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,phospho-2-dehydro-3-deoxyheptonate aldolase,,,shikimate pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30809210,PubMed,10.3389/fmicb.2019.00183,Front Microbiol. 2019 Feb 12;10:183,bioyongzhang@swu.edu.cn,"Virulence of the aroG1/2 or aroG1 mutants was completely diminished or significantly impaired in tomato and tobacco plants, but not the aroG2 mutants.",W Zhang 2019,2019,2 genes,Zhang-2019-Functional Characterization of Two,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13345,PHI:8884,UniProt,Q8XW15,GenBank,CAD16367,,,GMI1000,aroG1,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,phospho-2-dehydro-3-deoxyheptonate aldolase,,,shikimate pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30809210,PubMed,10.3389/fmicb.2019.00183,Front Microbiol. 2019 Feb 12;10:183,bioyongzhang@swu.edu.cn,"Virulence of the aroG1/2 or aroG1 mutants was completely diminished or significantly impaired in tomato and tobacco plants, but not the aroG2 mutants.",W Zhang 2019,2019,2 genes,Zhang-2019-Functional Characterization of Two,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13346,PHI:8885,UniProt,Q8Y1E7,GenBank,CAD14273,,,GMI1000,aroG2,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,phospho-2-dehydro-3-deoxyheptonate aldolase,,,shikimate pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30809210,PubMed,10.3389/fmicb.2019.00183,Front Microbiol. 2019 Feb 12;10:183,bioyongzhang@swu.edu.cn,"Virulence of the aroG1/2 or aroG1 mutants was completely diminished or significantly impaired in tomato and tobacco plants, but not the aroG2 mutants.",W Zhang 2019,2019,2 genes,Zhang-2019-Functional Characterization of Two,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13347,PHI:8884,UniProt,Q8XW15,GenBank,CAD16367,,,GMI1000,aroG1,,,,,,PHI:8885,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,phospho-2-dehydro-3-deoxyheptonate aldolase,,,shikimate pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30809210,PubMed,10.3389/fmicb.2019.00183,Front Microbiol. 2019 Feb 12;10:183,bioyongzhang@swu.edu.cn,"Virulence of the aroG1/2 or aroG1 mutants was completely diminished or significantly impaired in tomato and tobacco plants, but not the aroG2 mutants.",W Zhang 2019,2019,2 genes,Zhang-2019-Functional Characterization of Two,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13348,PHI:8885,UniProt,Q8Y1E7,GenBank,CAD14273,,,GMI1000,aroG2,,,,,,PHI:8884,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,phospho-2-dehydro-3-deoxyheptonate aldolase,,,shikimate pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30809210,PubMed,10.3389/fmicb.2019.00183,Front Microbiol. 2019 Feb 12;10:183,bioyongzhang@swu.edu.cn,"Virulence of the aroG1/2 or aroG1 mutants was completely diminished or significantly impaired in tomato and tobacco plants, but not the aroG2 mutants.",W Zhang 2019,2019,2 genes,Zhang-2019-Functional Characterization of Two,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13349,PHI:8886,UniProt,O68698,GenBank,AAC62576,,,KIM5,yopB,,,,,,,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),,,,spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13350,PHI:8887,UniProt,A0A384KVC5,GenBank,AE013942_4,,,KIM,ylrA (y3400),,,,,,PHI:8888; PHI:8889,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),,,,spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13351,PHI:8888,UniProt,A0A380PJQ0,GenBank,AE013942_3,,,KIM,ylrB (y3399),,,,,,PHI:8887; PHI:8889,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),,,,spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13352,PHI:8889,UniProt,A0A384KQ49,GenBank,AE013942_1,,,KIM,ylrC (y3397),,,,,,PHI:8887; PHI:8888,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),,,,spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13353,PHI:8886,UniProt,O68698,GenBank,AAC62576,,,KIM5,yopB,,,,,,,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13354,PHI:8887,UniProt,A0A384KVC5,GenBank,AE013942_4,,,KIM,ylrA (y3400),,,,,,,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13355,PHI:8888,UniProt,A0A380PJQ0,GenBank,AE013942_3,,,KIM,ylrB (y3399),,,,,,,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13356,PHI:8889,UniProt,A0A384KQ49,GenBank,AE013942_1,,,KIM,ylrC (y3397),,,,,,,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13357,PHI:8887,UniProt,A0A384KVC5,GenBank,AE013942_4,,,KIM,ylrA (y3400),,,,,,PHI:8888; PHI:8889,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13358,PHI:8888,UniProt,A0A380PJQ0,GenBank,AE013942_3,,,KIM,ylrB (y3399),,,,,,PHI:8887; PHI:8889,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13359,PHI:8889,UniProt,A0A384KQ49,GenBank,AE013942_1,,,KIM,ylrC (y3397),,,,,,PHI:8887; PHI:8888,632,Yersinia pestis,,KIM5,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30854334,PubMed,10.3389/fcimb.2019.00023,Front Cell Infect Microbiol. 2019 Feb 22;9:23,kschesser@med.miami.edu,"Engineered strains with deletions of y3397 (ylrC), y3399 (ylrB), or y3400 (ylrA), exhibited infection defects both in cultured cells and in the mouse.",S Schesser Bartra 2019,2019,4 genes,Schesser Bartra-2019-Chromosomally-Encoded Yer,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13360,PHI:8890,,no data found,,,,,,floA,,,,rny,UniProt: Q2FZ08; GenBank: BAF96735,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,fotillin-homolog protein,,,,reduced virulence,,,,,,,,,,no,zaragozic acid,zaragozic acid: CHEBI:75170,,,,,gene mutation; gene complementation,,,YVS,28669526,PubMed,10.1016/j.chembiol.2017.05.027,Cell Chem Biol. 2017 Jul 20;24(7):845-857.e6,dlopez@cnb.csic.es,Small-molecule inhibitors of FloA oligomerization reduce Rny activity and attenuate virulence in staphylococcal infections.,G Koch 2017,2017,2 genes,Koch-2017-Attenuating Staphylococcus aureus Vi,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13361,PHI:8891,UniProt,Q2FZ08,GenBank,BAF96735,,,,rny,,,,floA,UniProt: no data found; GenBank: no data found,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ribonuclease Y,,,,reduced virulence,,,,,,,,,,no,zaragozic acid,zaragozic acid: CHEBI:75170,,,,,gene mutation,,,YVS,28669526,PubMed,10.1016/j.chembiol.2017.05.027,Cell Chem Biol. 2017 Jul 20;24(7):845-857.e6,dlopez@cnb.csic.es,Small-molecule inhibitors of FloA oligomerization reduce Rny activity and attenuate virulence in staphylococcal infections.,G Koch 2017,2017,2 genes,Koch-2017-Attenuating Staphylococcus aureus Vi,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13362,PHI:8890,,no data found,,,,,,floA,,,,rny,UniProt: Q2FZ08; GenBank: BAF96735,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,fotillin-homolog protein,,,,reduced virulence,,,,,,,,,,no,zaragozic acid,zaragozic acid: CHEBI:75170,,,,,gene mutation; gene complementation,,,YVS,28669526,PubMed,10.1016/j.chembiol.2017.05.027,Cell Chem Biol. 2017 Jul 20;24(7):845-857.e6,dlopez@cnb.csic.es,Small-molecule inhibitors of FloA oligomerization reduce Rny activity and attenuate virulence in staphylococcal infections.,G Koch 2017,2017,2 genes,Koch-2017-Attenuating Staphylococcus aureus Vi,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13363,PHI:8892,UniProt,Q5ADP6,GenBank,AOW28708,,,SC5314,Sus1,chromosome 3,,,,,,5476,Candida albicans,,DAY1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,kidney,transcription and mRNA export factor,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,29326041,PubMed,10.1016/j.bbrc.2018.01.044,Biochem Biophys Res Commun. 2018 Feb 5;496(2):253-259,nklimingchun@163.com,"Sus1Δ/Δ displayed hyper-sensitivity to extracellular oxidative stress, enhanced ROS accumulation and severe oxidative stress-related cell death.",C Xiao 2018,2018,1 gene,Xiao-2018-Role of the mRNA export factor Sus1,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13364,PHI:8893,UniProt,G4MSZ4,GenBank,EHA54653,,,70-15,RGS1 (MGG_14517),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143189,Y-34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,developmental regulator,,,DHN-melanin biosynthesis pathway,increased virulence (hypervirulence),,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30874825,PubMed,10.1007/s00203-019-01646-8,Arch Microbiol. 2019 Mar 14,czhe@hainu.edu.cn,The melanin content of the single and double mutants was remarkably lower than that of the WT.,H Na 2019,2019,2 genes,Na-2019-Synergistic deletion of RGS1 and COS1,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13365,PHI:8894,,no data found,,,,,,COS1,,,,,,,318829,Magnaporthe oryzae,1143189,Y-34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,uncharacterized protein,,,DHN-melanin biosynthesis pathway,increased virulence (hypervirulence),,no,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30874825,PubMed,10.1007/s00203-019-01646-8,Arch Microbiol. 2019 Mar 14,czhe@hainu.edu.cn,The melanin content of the single and double mutants was remarkably lower than that of the WT.,H Na 2019,2019,2 genes,Na-2019-Synergistic deletion of RGS1 and COS1,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13366,PHI:8893,UniProt,G4MSZ4,GenBank,EHA54653,,,70-15,RGS1 (MGG_14517),chromosome 2,,,,,PHI:8894,318829,Magnaporthe oryzae,1143189,Y-34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,developmental regulator,,,DHN-melanin biosynthesis pathway,reduced virulence,,yes,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,30874825,PubMed,10.1007/s00203-019-01646-8,Arch Microbiol. 2019 Mar 14,czhe@hainu.edu.cn,The melanin content of the single and double mutants was remarkably lower than that of the WT.,H Na 2019,2019,2 genes,Na-2019-Synergistic deletion of RGS1 and COS1,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13367,PHI:8894,,no data found,,,,,,COS1,,,,,,PHI:8893,318829,Magnaporthe oryzae,1143189,Y-34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,uncharacterized protein,,,DHN-melanin biosynthesis pathway,reduced virulence,,yes,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full,,,YVS,30874825,PubMed,10.1007/s00203-019-01646-8,Arch Microbiol. 2019 Mar 14,czhe@hainu.edu.cn,The melanin content of the single and double mutants was remarkably lower than that of the WT.,H Na 2019,2019,2 genes,Na-2019-Synergistic deletion of RGS1 and COS1,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13368,PHI:8895,UniProt,Q59LV5,GenBank,AOW30998,,,SC5314,Pem1 (CR_02540W_A),chromosome R,,,,,PHI:8896,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,phosphatidylethanolamine N-methyltransferase,,,Kennedy pathway,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30792701,PubMed,10.3389/fmicb.2019.00086,Front Microbiol. 2019 Feb 7;10:86,treynol6@utk.edu,"Thus, the PENO1-EPT1 and pem1Δ/Δ pem2Δ/Δ mutants both accumulated PE and exhibited hypervirulence.",R N Tams 2019,2019,3 genes,Tams-2019-Overproduction of Phospholipids by t,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13369,PHI:8896,UniProt,A0A1D8PKM5,GenBank,AOW28663,,,SC5314,Pem2 (C3_06570C_A),chromosome 3,,,,,PHI:8895,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,phosphatidyl-N-methylethanolamine N-methyltransferase,,,Kennedy pathway,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30792701,PubMed,10.3389/fmicb.2019.00086,Front Microbiol. 2019 Feb 7;10:86,treynol6@utk.edu,"Thus, the PENO1-EPT1 and pem1Δ/Δ pem2Δ/Δ mutants both accumulated PE and exhibited hypervirulence.",R N Tams 2019,2019,3 genes,Tams-2019-Overproduction of Phospholipids by t,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13370,PHI:8897,UniProt,Q59M00,GenBank,AOW30624,,,SC5314,Ept1 (C7_02690C_A),chromosome 7,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,bifunctional diacylglycerol cholinephosphotransferase/ethanolaminephosphotransferase,,,Kennedy pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30792701,PubMed,10.3389/fmicb.2019.00086,Front Microbiol. 2019 Feb 7;10:86,treynol6@utk.edu,"Thus, the PENO1-EPT1 and pem1Δ/Δ pem2Δ/Δ mutants both accumulated PE and exhibited hypervirulence.",R N Tams 2019,2019,3 genes,Tams-2019-Overproduction of Phospholipids by t,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13371,PHI:8897,UniProt,Q59M00,GenBank,AOW30624,,,SC5314,Ept1 (C7_02690C_A),chromosome 7,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,bifunctional diacylglycerol cholinephosphotransferase/ethanolaminephosphotransferase,,,Kennedy pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30792701,PubMed,10.3389/fmicb.2019.00086,Front Microbiol. 2019 Feb 7;10:86,treynol6@utk.edu,"Thus, the PENO1-EPT1 and pem1Δ/Δ pem2Δ/Δ mutants both accumulated PE and exhibited hypervirulence.",R N Tams 2019,2019,3 genes,Tams-2019-Overproduction of Phospholipids by t,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13372,PHI:8897,UniProt,Q59M00,GenBank,AOW30624,,,SC5314,Ept1 (C7_02690C_A),chromosome 7,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),FaDu cell line,,,oral epithelial cell,bifunctional diacylglycerol cholinephosphotransferase/ethanolaminephosphotransferase,,,Kennedy pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30792701,PubMed,10.3389/fmicb.2019.00086,Front Microbiol. 2019 Feb 7;10:86,treynol6@utk.edu,"The ept11/1 mutant exhibited decreased cytotoxicity against oral epithelial cells in vitro, whereas the EPT1 overexpression strain exhibited increased cytotoxicity.",R N Tams 2019,2019,3 genes,Tams-2019-Overproduction of Phospholipids by t,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13373,PHI:8897,UniProt,Q59M00,GenBank,AOW30624,,,SC5314,Ept1 (C7_02690C_A),chromosome 7,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),FaDu cell line,,,oral epithelial cell,bifunctional diacylglycerol cholinephosphotransferase/ethanolaminephosphotransferase,,,Kennedy pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30792701,PubMed,10.3389/fmicb.2019.00086,Front Microbiol. 2019 Feb 7;10:86,treynol6@utk.edu,"The ept11/1 mutant exhibited decreased cytotoxicity against oral epithelial cells in vitro, whereas the EPT1 overexpression strain exhibited increased cytotoxicity.",R N Tams 2019,2019,3 genes,Tams-2019-Overproduction of Phospholipids by t,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13374,PHI:8898,UniProt,Q8ZFR1,GenBank,CAL20275,,,CO92,cobB (Yp_1760),,,,,,,632,Yersinia pestis,,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,protein deacetylase,,,,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29610260,PubMed,10.1128/IAI.00224-18,Infect Immun. 2018 May 22;86(6). pii: e00224-18,zmduams@163.com,"Protein acetylation impairment in cobB and yfiQ mutants greatly decreased bacterial tolerance to cold, hot, high-salt, and acidic environments.",W Liu 2019,2019,2 genes,Liu-2018-Protein Acetylation Mediated by YfiQ,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13375,PHI:8899,UniProt,Q8D179,GenBank,AE013695_1,,,KIM,yfiQ (Yp_0659),,,,,,,632,Yersinia pestis,,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,protein acetyltransferase,,,,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,29610260,PubMed,10.1128/IAI.00224-18,Infect Immun. 2018 May 22;86(6). pii: e00224-18,zmduams@163.com,"Protein acetylation impairment in cobB and yfiQ mutants greatly decreased bacterial tolerance to cold, hot, high-salt, and acidic environments.",W Liu 2019,2019,2 genes,Liu-2018-Protein Acetylation Mediated by YfiQ,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13376,PHI:8900,,no data found,,,,,,AtrR,,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,transcription factor,,,,loss of pathogenicity,,,,,,,,,,no,voriconazole; fluconazole,voriconazole: CHEBI:10023; fluconazole: CHEBI:46081,,,,,gene deletion: full,,,YVS,30862750,PubMed,10.1128/mBio.02563-18,MBio. 2019 Mar 12;10(2). pii: e02563-18,scott-moye-rowley@uiowa.edu,A loss of atrR rendered the resulting mutant strain avirulent.,S Paul 2019,2019,2 genes,Paul-2019-AtrR Is an Essential Determinant of,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13377,PHI:8900,,no data found,,,,,,AtrR,,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,transcription factor,,,,reduced virulence,,,,,,,,,,no,voriconazole,voriconazole: CHEBI:10023,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30862750,PubMed,10.1128/mBio.02563-18,MBio. 2019 Mar 12;10(2). pii: e02563-18,scott-moye-rowley@uiowa.edu,Elevating the expression of AtrR via insertion of the hspA promoter led to a delay in mortality caused by this strain.,S Paul 2019,2019,2 genes,Paul-2019-AtrR Is an Essential Determinant of,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13378,PHI:8901,UniProt,E9RBG1,GenBank,EAL90765,,,Af293,abcG1,chromosome 1,,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,ATP-binding cassette (ABC) transporter,,,,unaffected pathogenicity,,,,,,,,,,no,voriconazole,voriconazole: CHEBI:10023,,,,,gene mutation,,,YVS,30862750,PubMed,10.1128/mBio.02563-18,MBio. 2019 Mar 12;10(2). pii: e02563-18,scott-moye-rowley@uiowa.edu,Loss of the abcG1 gene did not have an observable effect on virulence.,S Paul 2019,2019,2 genes,Paul-2019-AtrR Is an Essential Determinant of,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13379,PHI:8902,UniProt,A0A125YWK4,GenBank,EPR63320,,,GT1,GRA9 type I (TGGT1_251540),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,dense granule protein GRA9,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30849416,PubMed,10.1016/j.molbiopara.2019.01.003,Mol Biochem Parasitol. 2019 Mar 5;229:53-61,gen@obihiro.ac.jp,The survival rate was not significantly different between BALB/c mice infected with RH and RHΔGRA9 strains.,H Guo 2019,2019,2 genes,Guo-2019-Characterization of strain-specific p,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13380,PHI:8903,UniProt,A0A125YVM0,GenBank,EPT25219,,,ME49,GRA9 type II (TGME49_251540),chromosome XII,,,,,,5811,Toxoplasma gondii,,PLK,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,dense granule protein GRA9,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30849416,PubMed,10.1016/j.molbiopara.2019.01.003,Mol Biochem Parasitol. 2019 Mar 5;229:53-61,gen@obihiro.ac.jp,PLKΔGRA9 parasites exhibit attenuated virulence in mice.,H Guo 2019,2019,2 genes,Guo-2019-Characterization of strain-specific p,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13381,PHI:8902,UniProt,A0A125YWK4,GenBank,EPR63320,,,GT1,GRA9 type I (TGGT1_251540),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,dense granule protein GRA9,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30849416,PubMed,10.1016/j.molbiopara.2019.01.003,Mol Biochem Parasitol. 2019 Mar 5;229:53-61,gen@obihiro.ac.jp,"GRA9 was dispensable during replication of parasites in host cells, and the invasive ability of both RHΔGRA9 and PLKΔGRA9 strains was inhibited.",H Guo 2019,2019,2 genes,Guo-2019-Characterization of strain-specific p,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13382,PHI:8903,UniProt,A0A125YVM0,GenBank,EPT25219,,,ME49,GRA9 type II (TGME49_251540),chromosome XII,,,,,,5811,Toxoplasma gondii,,PLK,toxoplasmosis,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,dense granule protein GRA9,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30849416,PubMed,10.1016/j.molbiopara.2019.01.003,Mol Biochem Parasitol. 2019 Mar 5;229:53-61,gen@obihiro.ac.jp,"GRA9 was dispensable during replication of parasites in host cells, and the invasive ability of both RHΔGRA9 and PLKΔGRA9 strains was inhibited.",H Guo 2019,2019,2 genes,Guo-2019-Characterization of strain-specific p,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13383,PHI:8904,UniProt,A0A1D8PFF4,GenBank,AOW26845,,,SC5314,VPH2,chromosome 1,,,,,,5476,Candida albicans,,SN76,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,vacuolar-type H+-ATPase,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,reduced,,no,caspofungin; calcofluor white (CFW); hygromycin B; sorbitol,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011; hygromycin B: CHEBI:16976; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,29522815,PubMed,10.1016/j.fgb.2018.03.001,Fungal Genet Biol. 2018 May;114:1-11,nklimingchun@163.com,The vph2Δ/Δ and vma6Δ/Δ mutants displayed decreased cell wall stress resistance and CWI induction.,C Jia 2018,2018,2 genes,Jia-2018-Roles of VPH2 and VMA6 in localizatio,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13384,PHI:8905,UniProt,A0A1D8PKX3,GenBank,AOW28795,,,SC5314,VMA6,chromosome 4,,,,,,5476,Candida albicans,,SN76,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,vacuolar-type H+-ATPase,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,reduced,,no,caspofungin; calcofluor white (CFW); hygromycin B; sorbitol,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011; hygromycin B: CHEBI:16976; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,29522815,PubMed,10.1016/j.fgb.2018.03.001,Fungal Genet Biol. 2018 May;114:1-11,nklimingchun@163.com,The vph2Δ/Δ and vma6Δ/Δ mutants displayed decreased cell wall stress resistance and CWI induction.,C Jia 2018,2018,2 genes,Jia-2018-Roles of VPH2 and VMA6 in localizatio,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13385,PHI:8906,UniProt,A7H2F1,GenBank,ABS43157,,,269.97,HtrA,,,,,,,197,Campylobacter jejuni,354242,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30805031,PubMed,10.1186/s13099-019-0283-z,Gut Pathog. 2019 Feb 13;11:4,Steffen.Backert@fau.de,Host gene alteration data available for occludin. ΔHtrA deletion mutant adhered to and invaded into host cell line at significant lower levels compared to wild-type bacteria.,A Harrer 2019,2019,1 gene,Harrer-2019-Campylobacter jejuni enters gut ep,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13386,PHI:8907,,no data found,GenBank,XP_011318607,,,PH-1; NRRL 31084,FgVPS23 (FGSG_02656),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,ESCRT (endosomal sorting complexes required for transport) protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,Congo red; calcofluor white (CFW); SDS; NaCl; KCl; H2O2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30809208,PubMed,10.3389/fmicb.2019.00180,Front Microbiol. 2019 Feb 12;10:180,yxxc19204@126.com,"ESCRT deletion mutants displayed severe defects in growth, deoxynivalenol (DON) production, virulence, sexual and asexual reproduction.",Q Xie 2019,2019,9 genes,Xie-2019-Component Interaction of ESCRT Comple,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13387,PHI:8908,UniProt,I1R9X6,GenBank,CEF72194,,,PH-1,FgVPS28 (FGSG_00291),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,ESCRT (endosomal sorting complexes required for transport) protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,Congo red; calcofluor white (CFW); SDS; NaCl; KCl; H2O2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30809208,PubMed,10.3389/fmicb.2019.00180,Front Microbiol. 2019 Feb 12;10:180,yxxc19204@126.com,"ESCRT deletion mutants displayed severe defects in growth, deoxynivalenol (DON) production, virulence, sexual and asexual reproduction.",Q Xie 2019,2019,9 genes,Xie-2019-Component Interaction of ESCRT Comple,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13388,PHI:8909,UniProt,I1RJT8,GenBank,CEF79072,,,PH-1,FgVPS22 (FGSG_04120),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,ESCRT (endosomal sorting complexes required for transport) protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,Congo red; calcofluor white (CFW); SDS; NaCl; KCl; H2O2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30809208,PubMed,10.3389/fmicb.2019.00180,Front Microbiol. 2019 Feb 12;10:180,yxxc19204@126.com,"ESCRT deletion mutants displayed severe defects in growth, deoxynivalenol (DON) production, virulence, sexual and asexual reproduction.",Q Xie 2019,2019,9 genes,Xie-2019-Component Interaction of ESCRT Comple,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13389,PHI:8910,,no data found,GenBank,XP_011320375,,,PH-1; NRRL 31084,FgVPS25 (FGSG_08401),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,ESCRT (endosomal sorting complexes required for transport) protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,Congo red; calcofluor white (CFW); SDS; NaCl; KCl; H2O2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30809208,PubMed,10.3389/fmicb.2019.00180,Front Microbiol. 2019 Feb 12;10:180,yxxc19204@126.com,"ESCRT deletion mutants displayed severe defects in growth, deoxynivalenol (DON) production, virulence, sexual and asexual reproduction.",Q Xie 2019,2019,9 genes,Xie-2019-Component Interaction of ESCRT Comple,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13390,PHI:8911,UniProt,I1RMR7,GenBank,CEF87172,,,PH-1,FgVPS36 (FGSG_05263),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,ESCRT (endosomal sorting complexes required for transport) protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,Congo red; calcofluor white (CFW); SDS; NaCl; KCl; H2O2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30809208,PubMed,10.3389/fmicb.2019.00180,Front Microbiol. 2019 Feb 12;10:180,yxxc19204@126.com,"ESCRT deletion mutants displayed severe defects in growth, deoxynivalenol (DON) production, virulence, sexual and asexual reproduction.",Q Xie 2019,2019,9 genes,Xie-2019-Component Interaction of ESCRT Comple,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13391,PHI:8912,UniProt,I1S297,GenBank,XP_011325503,,,PH-1; NRRL 31084,FgVPS20 (FGSG_10883),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,ESCRT (endosomal sorting complexes required for transport) protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,Congo red; calcofluor white (CFW); SDS; NaCl; KCl; H2O2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30809208,PubMed,10.3389/fmicb.2019.00180,Front Microbiol. 2019 Feb 12;10:180,yxxc19204@126.com,"ESCRT deletion mutants displayed severe defects in growth, deoxynivalenol (DON) production, virulence, sexual and asexual reproduction.",Q Xie 2019,2019,9 genes,Xie-2019-Component Interaction of ESCRT Comple,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13392,PHI:8913,UniProt,I1RJT0,GenBank,SCB65904,,,PH-1,FgVPS2 (FGSG_04112),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,ESCRT (endosomal sorting complexes required for transport) protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,YVS,30809208,PubMed,10.3389/fmicb.2019.00180,Front Microbiol. 2019 Feb 12;10:180,yxxc19204@126.com,"ESCRT deletion mutants displayed severe defects in growth, deoxynivalenol (DON) production, virulence, sexual and asexual reproduction.",Q Xie 2019,2019,9 genes,Xie-2019-Component Interaction of ESCRT Comple,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13393,PHI:8914,UniProt,I1S248,GenBank,CEF88739,,,PH-1,FgVPS24 (FGSG_10832),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,ESCRT (endosomal sorting complexes required for transport) protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,YVS,30809208,PubMed,10.3389/fmicb.2019.00180,Front Microbiol. 2019 Feb 12;10:180,yxxc19204@126.com,"ESCRT deletion mutants displayed severe defects in growth, deoxynivalenol (DON) production, virulence, sexual and asexual reproduction.",Q Xie 2019,2019,9 genes,Xie-2019-Component Interaction of ESCRT Comple,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13394,PHI:8915,UniProt,I1S074,GenBank,CEF75435,,,PH-1,FgVPS32 (FGSG_10092),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,ESCRT (endosomal sorting complexes required for transport) protein,,,,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,YVS,30809208,PubMed,10.3389/fmicb.2019.00180,Front Microbiol. 2019 Feb 12;10:180,yxxc19204@126.com,"ESCRT deletion mutants displayed severe defects in growth, deoxynivalenol (DON) production, virulence, sexual and asexual reproduction.",Q Xie 2019,2019,9 genes,Xie-2019-Component Interaction of ESCRT Comple,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13395,PHI:8916,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,,,,,,83560,Chlamydia muridarum,243161,Nigg,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,reproductive system,virulence plasmid protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30805313,PubMed,10.3389/fcimb.2019.00013,Front Cell Infect Microbiol. 2019 Feb 5;9:13,Liuyuanjun1980@126.com,The attenuated pathogenicity of the transformants harboring Pgp3 domain deletions was correlated with impaired invitro growth and significantly reduced infectivity in the mouse lower genital tract.,Y Huang 2019,2019,1 gene,Huang-2019-The Structural Integrity of Plasmid,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13396,PHI:8916,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,pgp3Δn N-terminus gene deletion mutant,,,,,83560,Chlamydia muridarum,243161,Nigg,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,reproductive system,virulence plasmid protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: partial,,,YVS,30805313,PubMed,10.3389/fcimb.2019.00013,Front Cell Infect Microbiol. 2019 Feb 5;9:13,Liuyuanjun1980@126.com,The attenuated pathogenicity of the transformants harboring Pgp3 domain deletions was correlated with impaired invitro growth and significantly reduced infectivity in the mouse lower genital tract.,Y Huang 2019,2019,1 gene,Huang-2019-The Structural Integrity of Plasmid,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13397,PHI:8916,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,pgp3Δc C-terminus gene deletion mutant,,,,,83560,Chlamydia muridarum,243161,Nigg,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,reproductive system,virulence plasmid protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: partial,,,YVS,30805313,PubMed,10.3389/fcimb.2019.00013,Front Cell Infect Microbiol. 2019 Feb 5;9:13,Liuyuanjun1980@126.com,The attenuated pathogenicity of the transformants harboring Pgp3 domain deletions was correlated with impaired invitro growth and significantly reduced infectivity in the mouse lower genital tract.,Y Huang 2019,2019,1 gene,Huang-2019-The Structural Integrity of Plasmid,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13398,PHI:8916,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,pgp3Δm M-terminus gene deletion mutant,,,,,83560,Chlamydia muridarum,243161,Nigg,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,reproductive system,virulence plasmid protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: partial,,,YVS,30805313,PubMed,10.3389/fcimb.2019.00013,Front Cell Infect Microbiol. 2019 Feb 5;9:13,Liuyuanjun1980@126.com,The attenuated pathogenicity of the transformants harboring Pgp3 domain deletions was correlated with impaired invitro growth and significantly reduced infectivity in the mouse lower genital tract.,Y Huang 2019,2019,1 gene,Huang-2019-The Structural Integrity of Plasmid,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13399,PHI:8916,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,,,,,,83560,Chlamydia muridarum,243161,Nigg,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,reproductive system,virulence plasmid protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30805313,PubMed,10.3389/fcimb.2019.00013,Front Cell Infect Microbiol. 2019 Feb 5;9:13,Liuyuanjun1980@126.com,The attenuated pathogenicity of the transformants harboring Pgp3 domain deletions was correlated with impaired invitro growth and significantly reduced infectivity in the mouse lower genital tract.,Y Huang 2019,2019,1 gene,Huang-2019-The Structural Integrity of Plasmid,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13400,PHI:8916,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,pgp3Δn N-terminus gene deletion mutant,,,,,83560,Chlamydia muridarum,243161,Nigg,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,reproductive system,virulence plasmid protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: partial,,,YVS,30805313,PubMed,10.3389/fcimb.2019.00013,Front Cell Infect Microbiol. 2019 Feb 5;9:13,Liuyuanjun1980@126.com,The attenuated pathogenicity of the transformants harboring Pgp3 domain deletions was correlated with impaired invitro growth and significantly reduced infectivity in the mouse lower genital tract.,Y Huang 2019,2019,1 gene,Huang-2019-The Structural Integrity of Plasmid,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13401,PHI:8916,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,pgp3Δc C-terminus gene deletion mutant,,,,,83560,Chlamydia muridarum,243161,Nigg,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,reproductive system,virulence plasmid protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: partial,,,YVS,30805313,PubMed,10.3389/fcimb.2019.00013,Front Cell Infect Microbiol. 2019 Feb 5;9:13,Liuyuanjun1980@126.com,The attenuated pathogenicity of the transformants harboring Pgp3 domain deletions was correlated with impaired invitro growth and significantly reduced infectivity in the mouse lower genital tract.,Y Huang 2019,2019,1 gene,Huang-2019-The Structural Integrity of Plasmid,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13402,PHI:8916,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,pgp3Δm M-terminus gene deletion mutant,,,,,83560,Chlamydia muridarum,243161,Nigg,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,reproductive system,virulence plasmid protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: partial,,,YVS,30805313,PubMed,10.3389/fcimb.2019.00013,Front Cell Infect Microbiol. 2019 Feb 5;9:13,Liuyuanjun1980@126.com,The attenuated pathogenicity of the transformants harboring Pgp3 domain deletions was correlated with impaired invitro growth and significantly reduced infectivity in the mouse lower genital tract.,Y Huang 2019,2019,1 gene,Huang-2019-The Structural Integrity of Plasmid,BATCH_091A,2019-03-01,MC,,,,,,,,,,,,,
,,Record 13403,PHI:8917,UniProt,Q6FPK7,GenBank,CAG60786,,,CBS 138,ICL1,chromosome J,,,,,,5478,Candida glabrata,,HTL,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,isocitrate lyase,,,glyoxylate cycle,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30808979,PubMed,10.1038/s41598-019-39117-1,Sci Rep. 2019 Feb 26;9(1):2843,leslie@upm.edu.my,The results showed the icl1Δ mutant was much more susceptible to macrophage killing than the WT control strain.,S Y Chew 2019,2019,1 gene,Chew-2019-Glyoxylate cycle gene ICL1 is essent,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13404,PHI:8917,UniProt,Q6FPK7,GenBank,CAG60786,,,CBS 138,ICL1,chromosome J,,,,,,5478,Candida glabrata,,HTL,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,isocitrate lyase,,,glyoxylate cycle,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30808979,PubMed,10.1038/s41598-019-39117-1,Sci Rep. 2019 Feb 26;9(1):2843,leslie@upm.edu.my,C. glabrata icl1Δ cells displayed significantly reduced biofilm growth in the presence of several alternative carbon sources.,S Y Chew 2019,2019,1 gene,Chew-2019-Glyoxylate cycle gene ICL1 is essent,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13405,PHI:8917,UniProt,Q6FPK7,GenBank,CAG60786,,,CBS 138,ICL1,chromosome J,,,,,,5478,Candida glabrata,,HTL,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,isocitrate lyase,,,glyoxylate cycle,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30808979,PubMed,10.1038/s41598-019-39117-1,Sci Rep. 2019 Feb 26;9(1):2843,leslie@upm.edu.my,C. glabrata icl1Δ cells displayed significantly reduced biofilm growth in the presence of several alternative carbon sources.,S Y Chew 2019,2019,1 gene,Chew-2019-Glyoxylate cycle gene ICL1 is essent,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13406,PHI:8918,UniProt,N1JJ94,GenBank,CCU83233,,,CSEP0064/BEC1054,DH14,,,,,,,34373,Blumeria graminis,62690,f. sp. tritici,powdery mildew (cereals); powdery mildew (grass),monocots,4565,Triticum aestivum (related: bread wheat),cv. Cerco,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30856238,PubMed,10.1371/journal.ppat.1007620,PLoS Pathog. 2019 Mar 11;15(3):e1007620,p.spanu@imperial.ac.uk,"Transgenic expression of CSEP0064/BEC1054 promoted virulence of diverse adapted pathogens (B. graminis f.sp. tritici, P. tabacina) in monocotyledonous (wheat) and dicotyledonous (N. benthamiana) plant species.",H G Pennington 2019,2019,1 gene,Pennington-2019-The fungal ribonuclease-like e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13407,PHI:8918,UniProt,N1JJ94,GenBank,CCU83233,,,CSEP0064/BEC1054,DH14,,,,,,,230439,Peronospora tabacina,,,blue mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30856238,PubMed,10.1371/journal.ppat.1007620,PLoS Pathog. 2019 Mar 11;15(3):e1007620,p.spanu@imperial.ac.uk,"Transgenic expression of CSEP0064/BEC1054 promoted virulence of diverse adapted pathogens (B. graminis f.sp. tritici, P. tabacina) in monocotyledonous (wheat) and dicotyledonous (N. benthamiana) plant species.",H G Pennington 2019,2019,1 gene,Pennington-2019-The fungal ribonuclease-like e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13408,PHI:8919,UniProt,O51534,GenBank,AAB91519,,,B31,Bgp (BB_0588),,,,,,,139,Borreliella burgdorferi,,B31 5A18,Lyme disease,primates,9606,Homo sapiens (related: human),HEK-293 cell line,,,epithelial cell,Borrelia glycosaminoglycan binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,29158428,PubMed,10.1128/IAI.00667-17,Infect Immun. 2018 Jan 22;86(2). pii: e00667-17,Parveeni@njms.rutgers.edu,"Loss of Bgp impaired spirochete adherence, infectivity, and tissue colonization, resulting in a reduction of inflammatory manifestations of Lyme disease.",S Schlachter 2017,2017,1 gene,Schlachter-2017-Borrelia burgdorferi glycosami,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13409,PHI:8919,UniProt,O51534,GenBank,AAB91519,,,B31,Bgp (BB_0588),,,,,,,139,Borreliella burgdorferi,,B31 5A18,Lyme disease,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,Borrelia glycosaminoglycan binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,29158428,PubMed,10.1128/IAI.00667-17,Infect Immun. 2018 Jan 22;86(2). pii: e00667-17,Parveeni@njms.rutgers.edu,"Loss of Bgp impaired spirochete adherence, infectivity, and tissue colonization, resulting in a reduction of inflammatory manifestations of Lyme disease.",S Schlachter 2017,2017,1 gene,Schlachter-2017-Borrelia burgdorferi glycosami,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13410,PHI:8919,UniProt,O51534,GenBank,AAB91519,,,B31,Bgp (BB_0588),,,,,,,139,Borreliella burgdorferi,,B31 5A18,Lyme disease,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,EAhy 926 cell,Borrelia glycosaminoglycan binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,29158428,PubMed,10.1128/IAI.00667-17,Infect Immun. 2018 Jan 22;86(2). pii: e00667-17,Parveeni@njms.rutgers.edu,"Loss of Bgp impaired spirochete adherence, infectivity, and tissue colonization, resulting in a reduction of inflammatory manifestations of Lyme disease.",S Schlachter 2017,2017,1 gene,Schlachter-2017-Borrelia burgdorferi glycosami,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13411,PHI:8919,UniProt,O51534,GenBank,AAB91519,,,B31,Bgp (BB_0588),,,,,,,139,Borreliella burgdorferi,,B31 5A18,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,ear; skin; bladder,Borrelia glycosaminoglycan binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption; gene complementation,,,YVS,29158428,PubMed,10.1128/IAI.00667-17,Infect Immun. 2018 Jan 22;86(2). pii: e00667-17,Parveeni@njms.rutgers.edu,"Loss of Bgp impaired spirochete adherence, infectivity, and tissue colonization, resulting in a reduction of inflammatory manifestations of Lyme disease.",S Schlachter 2017,2017,1 gene,Schlachter-2017-Borrelia burgdorferi glycosami,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13412,PHI:8920,UniProt,A0A223HBP4,GenBank,AST35797,,,28185,ZafA,,,,,,,523103,Trichophyton mentagrophytes,,360-A,ringworm,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,skin,zinc-responsive activating factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30781401,PubMed,10.3390/ijms20040848,Int J Mol Sci. 2019 Feb 15;20(4). pii: E848,zhxk1983@sina.com,"ZafA-hph's growth performance, reproduction ability, and zinc ion absorption capacity were significantly lower than the wild-type T. mentagrophytes.",P Dai 2019,2019,1 gene,Dai-2019-ZafA Gene Is Important for Trichophyt,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13413,PHI:8921,UniProt,A0A1D9ELP8,GenBank,AOY64023,,,8ra,EadM,,,,,,,53413,Xanthomonas axonopodis,,pv. glycines strain 8ra,bacterial blight,eudicots,3847,Glycine max (related: soybean),cv. Jinju1,,,leaf,DNA methyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,ciprofloxacin; D-sorbitol; isopropyl beta-D-1-thiogalactopyranoside (IPTG),ciprofloxacin: CHEBI:100241; D-sorbitol: CHEBI:17924; isopropyl beta-D-1-thiogalactopyranoside (IPTG): CHEBI:61448,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30792399,PubMed,10.1038/s41598-019-38650-3,Sci Rep. 2019 Feb 21;9(1):2446,swhan@cau.ac.kr,"Xag(EadM) showed decreased stress tolerance against ciprofloxacin and sorbitol, but enhanced resistance to desiccation.",H J Park 2019,2019,1 gene,Park-2019-Functional characterization of a put,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13414,PHI:8922,UniProt,Q2YPX3,GenBank,AAB97420,,,2308,lon,,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,Lon protease,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"SDS; H2O2; 2,2'-dipyridyl; ampicillin; penicillin G; carbenicillin; ciprofloxacin; tetracycline; streptomycin","SDS: CHEBI:8984; H2O2: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351; ampicillin: CHEBI:28971; penicillin G: CHEBI:18208; carbenicillin: CHEBI:3393; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; streptomycin: CHEBI:17076",,,,,gene mutation; gene complementation,,,YVS,30797816,PubMed,10.1016/j.micpath.2019.01.010,Microb Pathog. 2019 Feb 21;130:112-119,chensa727@vip.126.com,Lon protein was involved in resistance to various stress conditions and all the beta-lactam antibiotics tested.,Y Liu 2019,2019,1 gene,Liu-2019-RNA-seq reveals the critical role of,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13415,PHI:8922,UniProt,Q2YPX3,GenBank,AAB97420,,,2308,lon,,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,Lon protease,,,,reduced virulence,,,,,,,,reduced,,no,"SDS; H2O2; 2,2'-dipyridyl; ampicillin; penicillin G; carbenicillin; ciprofloxacin; tetracycline; streptomycin","SDS: CHEBI:8984; H2O2: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351; ampicillin: CHEBI:28971; penicillin G: CHEBI:18208; carbenicillin: CHEBI:3393; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; streptomycin: CHEBI:17076",,,,,gene mutation; gene complementation,,,YVS,30797816,PubMed,10.1016/j.micpath.2019.01.010,Microb Pathog. 2019 Feb 21;130:112-119,chensa727@vip.126.com,Lon protein was involved in resistance to various stress conditions and all the beta-lactam antibiotics tested.,Y Liu 2019,2019,1 gene,Liu-2019-RNA-seq reveals the critical role of,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13416,PHI:8923,UniProt,I1RMV4,GenBank,HG970334,,,PH-1,FgHLTF1 (FGSG_05304),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 33,,,inflorescence,putative histone-like transcription factor,,,high osmolarity glycerol response pathway,reduced virulence,,,yes,,,,reduced,reduced; aberrant,,no,sorbitol; KCl; NaCl,sorbitol: CHEBI:30911; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,30852625,PubMed,10.1007/s00294-019-00953-3,Curr Genet. 2019 Mar 9,zhywang@zju.edu.cn,FgHLTF1 was a negative regulator of DON biosynthesis in F. graminearum.,W Lv 2019,2019,1 gene,Lv-2019-The putative histone-like transcriptio,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13417,PHI:8923,UniProt,I1RMV4,GenBank,HG970334,,,PH-1,FgHLTF1 (FGSG_05304),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 33,,,inflorescence,putative histone-like transcription factor,,,high osmolarity glycerol response pathway,reduced virulence,,,yes,,,,reduced,reduced; aberrant,,no,sorbitol; KCl; NaCl,sorbitol: CHEBI:30911; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,30852625,PubMed,10.1007/s00294-019-00953-3,Curr Genet. 2019 Mar 9,zhywang@zju.edu.cn,FgHLTF1 was a negative regulator of DON biosynthesis in F. graminearum.,W Lv 2019,2019,1 gene,Lv-2019-The putative histone-like transcriptio,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13418,PHI:8924,UniProt,I1RZR4,GenBank,HG970332,,,PH-1,FgPLD1 (FGSG_09917),chromosome 1,,,,,,5518,Fusarium graminearum,,SF01-3,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,phospholipase,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29079075,PubMed,10.1016/j.fgb.2017.10.007,Fungal Genet Biol. 2017 Dec;109:46-52,liangyc@sdau.edu.cn,"Deletion of FgPLD1, but not FgPLD2 or FgPLD3, affected hyphal growth, conidiation, perithecium formation and showed reduced deoxynivalenol (DON) production.",M Ding 2017,2017,3 genes,Ding-2017-Differential roles of three FgPLD ge,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13419,PHI:8925,UniProt,I1RE91,GenBank,HG970332,,,PH-1,FgPLD2 (FGSG_01973),chromosome 1,,,,,,5518,Fusarium graminearum,,SF01-3,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,phospholipase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29079075,PubMed,10.1016/j.fgb.2017.10.007,Fungal Genet Biol. 2017 Dec;109:46-52,liangyc@sdau.edu.cn,"Deletion of FgPLD1, but not FgPLD2 or FgPLD3, affected hyphal growth, conidiation, perithecium formation and showed reduced deoxynivalenol (DON) production.",M Ding 2017,2017,3 genes,Ding-2017-Differential roles of three FgPLD ge,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13420,PHI:8926,,no data found,GenBank,XP_011324813,,,PH-1; NRRL 31084,FgPLD3 (FGSG_06175),chromosome 3,,,,,,5518,Fusarium graminearum,,SF01-3,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29079075,PubMed,10.1016/j.fgb.2017.10.007,Fungal Genet Biol. 2017 Dec;109:46-52,liangyc@sdau.edu.cn,"Deletion of FgPLD1, but not FgPLD2 or FgPLD3, affected hyphal growth, conidiation, perithecium formation and showed reduced deoxynivalenol (DON) production.",M Ding 2017,2017,3 genes,Ding-2017-Differential roles of three FgPLD ge,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13421,PHI:8924,UniProt,I1RZR4,GenBank,HG970332,,,PH-1,FgPLD1 (FGSG_09917),chromosome 1,,,,,,5518,Fusarium graminearum,,SF01-3,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,phospholipase,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29079075,PubMed,10.1016/j.fgb.2017.10.007,Fungal Genet Biol. 2017 Dec;109:46-52,liangyc@sdau.edu.cn,"Deletion of FgPLD1, but not FgPLD2 or FgPLD3, affected hyphal growth, conidiation, perithecium formation and showed reduced deoxynivalenol (DON) production.",M Ding 2017,2017,3 genes,Ding-2017-Differential roles of three FgPLD ge,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13422,PHI:8925,UniProt,I1RE91,GenBank,HG970332,,,PH-1,FgPLD2 (FGSG_01973),chromosome 1,,,,,,5518,Fusarium graminearum,,SF01-3,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,phospholipase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29079075,PubMed,10.1016/j.fgb.2017.10.007,Fungal Genet Biol. 2017 Dec;109:46-52,liangyc@sdau.edu.cn,"Deletion of FgPLD1, but not FgPLD2 or FgPLD3, affected hyphal growth, conidiation, perithecium formation and showed reduced deoxynivalenol (DON) production.",M Ding 2017,2017,3 genes,Ding-2017-Differential roles of three FgPLD ge,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13423,PHI:8926,,no data found,GenBank,XP_011324813,,,PH-1; NRRL 31084,FgPLD3 (FGSG_06175),chromosome 3,,,,,,5518,Fusarium graminearum,,SF01-3,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29079075,PubMed,10.1016/j.fgb.2017.10.007,Fungal Genet Biol. 2017 Dec;109:46-52,liangyc@sdau.edu.cn,"Deletion of FgPLD1, but not FgPLD2 or FgPLD3, affected hyphal growth, conidiation, perithecium formation and showed reduced deoxynivalenol (DON) production.",M Ding 2017,2017,3 genes,Ding-2017-Differential roles of three FgPLD ge,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13424,PHI:8927,UniProt,A4QTE3,GenBank,EHA52813,,,70-15,MoSCAD1 (MGG_05096),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,3-ketoacyl-CoA reductase,,,β-oxidation pathway,reduced virulence,,,,,,wild type,,reduced; aberrant,,no,Congo red; calcofluor white; dithiothreitol (DTT); NaCl; SDS,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30822500,PubMed,10.1016/j.fgb.2019.02.010,Fungal Genet Biol. 2019 Feb 27;127:23-34,jk_norvienyeku@fafu.edu.cn,Deletion of MoSCAD2 triggered the most dramatic reduction in virulence while the disruption of MoSCAD1 and ΔMoSCAD3 only caused a mild decrease in virulence of ΔMoscad1 and ΔMoscad3 strains.,S R Aliyu 2019,2019,3 genes,Aliyu-2019-Disruption of putative short-chain,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13425,PHI:8928,UniProt,G4NFW7,GenBank,EHA46924,,,70-15,MoSCAD2 (MGG_08690),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,3-hydroxy acylCoA dehydrogenase,,,β-oxidation pathway,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,reduced,no,Congo red; calcofluor white; dithiothreitol (DTT); NaCl; SDS,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30822500,PubMed,10.1016/j.fgb.2019.02.010,Fungal Genet Biol. 2019 Feb 27;127:23-34,jk_norvienyeku@fafu.edu.cn,Deletion of MoSCAD2 triggered the most dramatic reduction in virulence while the disruption of MoSCAD1 and ΔMoSCAD3 only caused a mild decrease in virulence of ΔMoscad1 and ΔMoscad3 strains.,S R Aliyu 2019,2019,3 genes,Aliyu-2019-Disruption of putative short-chain,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13426,PHI:8929,UniProt,G4MWK9,GenBank,EHA54257,,,70-15,MoSCAD3 (MGG_01180),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,short-chain specific acyl-CoA dehydrogenase,,,β-oxidation pathway,reduced virulence,,,,,,wild type,,wild type,,no,Congo red; calcofluor white; dithiothreitol (DTT); NaCl; SDS,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30822500,PubMed,10.1016/j.fgb.2019.02.010,Fungal Genet Biol. 2019 Feb 27;127:23-34,jk_norvienyeku@fafu.edu.cn,Deletion of MoSCAD2 triggered the most dramatic reduction in virulence while the disruption of MoSCAD1 and ΔMoSCAD3 only caused a mild decrease in virulence of ΔMoscad1 and ΔMoscad3 strains.,S R Aliyu 2019,2019,3 genes,Aliyu-2019-Disruption of putative short-chain,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13427,PHI:8928,UniProt,G4NFW7,GenBank,EHA46924,,,70-15,MoSCAD2 (MGG_08690),chromosome 6,,,,,PHI:8927,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,3-hydroxy acylCoA dehydrogenase,,,β-oxidation pathway,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,reduced,no,Congo red; calcofluor white; dithiothreitol (DTT); NaCl; SDS,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30822500,PubMed,10.1016/j.fgb.2019.02.010,Fungal Genet Biol. 2019 Feb 27;127:23-34,jk_norvienyeku@fafu.edu.cn,Deletion of MoSCAD2 triggered the most dramatic reduction in virulence while the disruption of MoSCAD1 and ΔMoSCAD3 only caused a mild decrease in virulence of ΔMoscad1 and ΔMoscad3 strains.,S R Aliyu 2019,2019,3 genes,Aliyu-2019-Disruption of putative short-chain,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13428,PHI:8927,UniProt,A4QTE3,GenBank,EHA52813,,,70-15,MoSCAD1 (MGG_05096),chromosome 3,,,,,PHI:8928,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,3-ketoacyl-CoA reductase,,,β-oxidation pathway,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,Congo red; calcofluor white; dithiothreitol (DTT); NaCl; SDS,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30822500,PubMed,10.1016/j.fgb.2019.02.010,Fungal Genet Biol. 2019 Feb 27;127:23-34,jk_norvienyeku@fafu.edu.cn,Deletion of MoSCAD2 triggered the most dramatic reduction in virulence while the disruption of MoSCAD1 and ΔMoSCAD3 only caused a mild decrease in virulence of ΔMoscad1 and ΔMoscad3 strains.,S R Aliyu 2019,2019,3 genes,Aliyu-2019-Disruption of putative short-chain,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13429,PHI:8927,UniProt,A4QTE3,GenBank,EHA52813,,,70-15,MoSCAD1 (MGG_05096),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,3-ketoacyl-CoA reductase,,,β-oxidation pathway,reduced virulence,,,,,,wild type,,reduced; aberrant,,no,Congo red; calcofluor white; dithiothreitol (DTT); NaCl; SDS,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30822500,PubMed,10.1016/j.fgb.2019.02.010,Fungal Genet Biol. 2019 Feb 27;127:23-34,jk_norvienyeku@fafu.edu.cn,Deletion of MoSCAD2 triggered the most dramatic reduction in virulence while the disruption of MoSCAD1 and ΔMoSCAD3 only caused a mild decrease in virulence of ΔMoscad1 and ΔMoscad3 strains.,S R Aliyu 2019,2019,3 genes,Aliyu-2019-Disruption of putative short-chain,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13430,PHI:8928,UniProt,G4NFW7,GenBank,EHA46924,,,70-15,MoSCAD2 (MGG_08690),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,3-hydroxy acylCoA dehydrogenase,,,β-oxidation pathway,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,reduced,no,Congo red; calcofluor white; dithiothreitol (DTT); NaCl; SDS,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30822500,PubMed,10.1016/j.fgb.2019.02.010,Fungal Genet Biol. 2019 Feb 27;127:23-34,jk_norvienyeku@fafu.edu.cn,Deletion of MoSCAD2 triggered the most dramatic reduction in virulence while the disruption of MoSCAD1 and ΔMoSCAD3 only caused a mild decrease in virulence of ΔMoscad1 and ΔMoscad3 strains.,S R Aliyu 2019,2019,3 genes,Aliyu-2019-Disruption of putative short-chain,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13431,PHI:8929,UniProt,G4MWK9,GenBank,EHA54257,,,70-15,MoSCAD3 (MGG_01180),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,short-chain specific acyl-CoA dehydrogenase,,,β-oxidation pathway,reduced virulence,,,,,,wild type,,wild type,,no,Congo red; calcofluor white; dithiothreitol (DTT); NaCl; SDS,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30822500,PubMed,10.1016/j.fgb.2019.02.010,Fungal Genet Biol. 2019 Feb 27;127:23-34,jk_norvienyeku@fafu.edu.cn,Deletion of MoSCAD2 triggered the most dramatic reduction in virulence while the disruption of MoSCAD1 and ΔMoSCAD3 only caused a mild decrease in virulence of ΔMoscad1 and ΔMoscad3 strains.,S R Aliyu 2019,2019,3 genes,Aliyu-2019-Disruption of putative short-chain,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13432,PHI:8928,UniProt,G4NFW7,GenBank,EHA46924,,,70-15,MoSCAD2 (MGG_08690),chromosome 6,,,,,PHI:8927,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,3-hydroxy acylCoA dehydrogenase,,,β-oxidation pathway,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,reduced,no,Congo red; calcofluor white; dithiothreitol (DTT); NaCl; SDS,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30822500,PubMed,10.1016/j.fgb.2019.02.010,Fungal Genet Biol. 2019 Feb 27;127:23-34,jk_norvienyeku@fafu.edu.cn,Deletion of MoSCAD2 triggered the most dramatic reduction in virulence while the disruption of MoSCAD1 and ΔMoSCAD3 only caused a mild decrease in virulence of ΔMoscad1 and ΔMoscad3 strains.,S R Aliyu 2019,2019,3 genes,Aliyu-2019-Disruption of putative short-chain,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13433,PHI:8927,UniProt,A4QTE3,GenBank,EHA52813,,,70-15,MoSCAD1 (MGG_05096),chromosome 3,,,,,PHI:8928,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,3-ketoacyl-CoA reductase,,,β-oxidation pathway,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,Congo red; calcofluor white; dithiothreitol (DTT); NaCl; SDS,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; dithiothreitol (DTT): CHEBI:42170; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30822500,PubMed,10.1016/j.fgb.2019.02.010,Fungal Genet Biol. 2019 Feb 27;127:23-34,jk_norvienyeku@fafu.edu.cn,Deletion of MoSCAD2 triggered the most dramatic reduction in virulence while the disruption of MoSCAD1 and ΔMoSCAD3 only caused a mild decrease in virulence of ΔMoscad1 and ΔMoscad3 strains.,S R Aliyu 2019,2019,3 genes,Aliyu-2019-Disruption of putative short-chain,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13434,PHI:8930,UniProt,A0A384JR79,GenBank,ATZ52897,,,B05.10,BcSHO1 (Bcin08p05150),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13435,PHI:8931,UniProt,A0A384K2E5,GenBank,ATZ56995,,,B05.10,BcSLN1 (Bcin14p01870),chromosome BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13436,PHI:8930,UniProt,A0A384JR79,GenBank,ATZ52897,,,B05.10,BcSHO1 (Bcin08p05150),chromosome BCIN08,,,,,PHI:8931,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13437,PHI:8931,UniProt,A0A384K2E5,GenBank,ATZ56995,,,B05.10,BcSLN1 (Bcin14p01870),chromosome BCIN14,,,,,PHI:8930,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13438,PHI:8930,UniProt,A0A384JR79,GenBank,ATZ52897,,,B05.10,BcSHO1 (Bcin08p05150),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13439,PHI:8931,UniProt,A0A384K2E5,GenBank,ATZ56995,,,B05.10,BcSLN1 (Bcin14p01870),chromosome BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13440,PHI:8930,UniProt,A0A384JR79,GenBank,ATZ52897,,,B05.10,BcSHO1 (Bcin08p05150),chromosome BCIN08,,,,,PHI:8931,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13441,PHI:8931,UniProt,A0A384K2E5,GenBank,ATZ56995,,,B05.10,BcSLN1 (Bcin14p01870),chromosome BCIN14,,,,,PHI:8930,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13442,PHI:8930,UniProt,A0A384JR79,GenBank,ATZ52897,,,B05.10,BcSHO1 (Bcin08p05150),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13443,PHI:8931,UniProt,A0A384K2E5,GenBank,ATZ56995,,,B05.10,BcSLN1 (Bcin14p01870),chromosome BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13444,PHI:8930,UniProt,A0A384JR79,GenBank,ATZ52897,,,B05.10,BcSHO1 (Bcin08p05150),chromosome BCIN08,,,,,PHI:8931,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13445,PHI:8931,UniProt,A0A384K2E5,GenBank,ATZ56995,,,B05.10,BcSLN1 (Bcin14p01870),chromosome BCIN14,,,,,PHI:8930,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,transmembrane osmosensor protein,,,high-osmolarity glycerol (HOG) signaling pathway,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,iprodione; procymidone; fludioxonil; NaCl; KCl; sorbitol,iprodione: CHEBI:28909; procymidone: CHEBI:8450; fludioxonil: CHEBI:81763; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,30858841,PubMed,10.3389/fmicb.2019.00328,Front Microbiol. 2019 Feb 25;10:328,gql3333@163.com,"ΔBcSln1-Sho1 produced much more, but smaller sclerotia than ΔBcSho1 and the wild-type (WT) strain, while ΔBcSln1 failed to develop sclerotia on all tested media, instead, formed a large number of conidia.",W Ren 2019,2019,2 genes,Ren-2019-The Sensor Proteins BcSho1 and BcSln1,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13446,PHI:8932,UniProt,A0A116Q7Z1,GenBank,CYV08090,,,LSS37,adhE,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,acetaldehyde-CoA/alcohol dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29247804,PubMed,10.1016/j.jprot.2017.12.001,J Proteomics. 2018 May 30;180:41-52,vszw@njau.edu.cn,Deletion of adhE attenuated the virulence of S. suis serotype 2.,Y Yu 2017,2017,1 gene,Yu-2017-Infection and adaption-based proteomic,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13447,PHI:8932,UniProt,A0A116Q7Z1,GenBank,CYV08090,,,LSS37,adhE,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,acetaldehyde-CoA/alcohol dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29247804,PubMed,10.1016/j.jprot.2017.12.001,J Proteomics. 2018 May 30;180:41-52,vszw@njau.edu.cn,AdhE was indispensable for adhesion to Caco-2 cells.,Y Yu 2017,2017,1 gene,Yu-2017-Infection and adaption-based proteomic,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13448,PHI:8932,UniProt,A0A116Q7Z1,GenBank,CYV08090,,,LSS37,adhE,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,acetaldehyde-CoA/alcohol dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29247804,PubMed,10.1016/j.jprot.2017.12.001,J Proteomics. 2018 May 30;180:41-52,vszw@njau.edu.cn,AdhE was indispensable for adhesion to Caco-2 cells.,Y Yu 2017,2017,1 gene,Yu-2017-Infection and adaption-based proteomic,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13449,PHI:8933,UniProt,Q6D803,GenBank,CAG74082,,,SCRI1043,rsmS (ECA1172),,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,soft rot (potato); blackleg disease (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Maris Piper,,,tuber,uncharacterized protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,carbapenem,carbapenem: CHEBI:46765,,,,,gene deletion: full,,,YVS,30872786,PubMed,10.1038/s41598-019-40970-3,Sci Rep. 2019 Mar 14;9(1):4525,gpcs2@cam.ac.uk,"Single rsmS mutants, overproduced plant cell wall degrading enzymes (pCWDes) and N-3-oxohexanoyl-homoserine lactone (OHHL) relative to wild type P. atrosepticum and exhibited hypervirulence in potato.",R E Monson 2019,2019,1 gene,Monson-2019-The rsmS (ybaM) mutation causes by,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13450,PHI:8934,UniProt,Q4WER9,GenBank,EAL85908,,,Af293,ldpA (Afu5g03980),chromosome 5,,,,,PHI:8935,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,"LysM domain protein, putative",,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white (CFW); Congo red; NaCl; KCl; sorbitol,calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,YVS,30833675,PubMed,10.1038/s41598-019-40039-1,Sci Rep. 2019 Mar 4;9(1):3345,y.muraosa@faculty.chiba-u.jp,The deletion of A. fumigatus ldpA and ldpB did not affect cell wall integrity or chitin content.,Y Muraosa 2019,2019,2 genes,Muraosa-2019-Characterisation of novel-cell-wa,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13451,PHI:8935,UniProt,Q4WRR0,GenBank,EAL90872,,,Af293,ldpB (Afu1g15420),chromosome 1,,,,,PHI:8934,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,LysM domain protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white (CFW); Congo red; NaCl; KCl; sorbitol,calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,YVS,30833675,PubMed,10.1038/s41598-019-40039-1,Sci Rep. 2019 Mar 4;9(1):3345,y.muraosa@faculty.chiba-u.jp,The deletion of A. fumigatus ldpA and ldpB did not affect cell wall integrity or chitin content.,Y Muraosa 2019,2019,2 genes,Muraosa-2019-Characterisation of novel-cell-wa,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13452,PHI:8936,UniProt,A0A2B6C4K2,GenBank,AAT32769,,,Ames Ancestor; A2084,HtrA,,,,,,,1392,Bacillus anthracis,260799,Sterne,anthrax,rodents,10090,Mus musculus (related: house mouse),ICR,,,,serine protease HtrA,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,30833938,PubMed,10.3389/fmicb.2019.00255,Front Microbiol. 2019 Feb 18;10:255,theodorc@iibr.gov.il,"The proteolytic activity of HtrA was essential for its autolysis and secretion, for the role of HtrA in stress resistance and for manifestation of B. anthracis virulence, and the unique PDZ domain was dispensable for all these processes.",M Israeli 2019,2019,1 gene,Israeli-2019-Distinct Contribution of the HtrA,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13453,PHI:8936,UniProt,A0A2B6C4K2,GenBank,AAT32769,,,Ames Ancestor; A2084,HtrA,,partial deletion encompassing the PDZ domain (htrAΔPDZ),,,,,1392,Bacillus anthracis,260799,Sterne,anthrax,rodents,10090,Mus musculus (related: house mouse),ICR,,,,serine protease HtrA,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: partial,,,YVS,30833938,PubMed,10.3389/fmicb.2019.00255,Front Microbiol. 2019 Feb 18;10:255,theodorc@iibr.gov.il,"The proteolytic activity of HtrA was essential for its autolysis and secretion, for the role of HtrA in stress resistance and for manifestation of B. anthracis virulence, and the unique PDZ domain was dispensable for all these processes.",M Israeli 2019,2019,1 gene,Israeli-2019-Distinct Contribution of the HtrA,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13454,PHI:8936,UniProt,A0A2B6C4K2,GenBank,AAT32769,,,Ames Ancestor; A2084,HtrA,,non-proteolytic form (point replacement mutation of the catalytic serine residue) htrAS255A,,,,,1392,Bacillus anthracis,260799,Sterne,anthrax,rodents,10090,Mus musculus (related: house mouse),ICR,,,,serine protease HtrA,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene mutation,,,YVS,30833938,PubMed,10.3389/fmicb.2019.00255,Front Microbiol. 2019 Feb 18;10:255,theodorc@iibr.gov.il,"The proteolytic activity of HtrA was essential for its autolysis and secretion, for the role of HtrA in stress resistance and for manifestation of B. anthracis virulence, and the unique PDZ domain was dispensable for all these processes.",M Israeli 2019,2019,1 gene,Israeli-2019-Distinct Contribution of the HtrA,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13455,PHI:8937,UniProt,Q9I0J4,GenBank,AE004693_3,,,PAO1,nuoI (PA2644),,,,,,PHI:8938,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,NADH-quinone oxidoreductase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13456,PHI:8938,UniProt,Q9I0J3,GenBank,AE004693_4,,,PAO1,nuoJ (PA2645),,,,,,PHI:8937,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,NADH-quinone oxidoreductase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13457,PHI:8939,UniProt,Q9HVN9,GenBank,AE004867_12,,,PAO1,ndh (PA4538),,,,,,PHI:8937; PHI:8938,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,NADH dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13458,PHI:8937,UniProt,Q9I0J4,GenBank,AE004693_3,,,PAO1,nuoI (PA2644),,,,,,PHI:8939; PHI:8938,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,NADH-quinone oxidoreductase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13459,PHI:8938,UniProt,Q9I0J3,GenBank,AE004693_4,,,PAO1,nuoJ (PA2645),,,,,,PHI:8939; PHI:8937,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,NADH-quinone oxidoreductase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13460,PHI:8940,UniProt,Q9HZL1,GenBank,AE004724_11,,,PAO1,nqrF (PA2994),,,,,,PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13461,PHI:8941,UniProt,Q9HZL0,GenBank,AE004724_12,,,PAO1,nqrE (PA2995),,,,,,PHI:8940; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13462,PHI:8942,UniProt,Q9HZK9,GenBank,AE004724_13,,,PAO1,nqrD (PA2996),,,,,,PHI:8940; PHI:8941; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13463,PHI:8943,UniProt,Q9HZK8,GenBank,AE004724_14,,,PAO1,nqrC (PA2997),,,,,,PHI:8940; PHI:8941; PHI:8942; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13464,PHI:8944,UniProt,Q9HZK7,GenBank,AE004724_15,,,PAO1,nqrB (PA2998),,,,,,PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13465,PHI:8945,UniProt,Q9HZK6,GenBank,AE004724_16,,,PAO1,nqrA (PA2999),,,,,,PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13466,PHI:8939,UniProt,Q9HVN9,GenBank,AE004867_12,,,PAO1,ndh (PA4538),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,NADH dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13467,PHI:8939,UniProt,Q9HVN9,GenBank,AE004867_12,,,PAO1,ndh (PA4538),,,,,,PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,NADH dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13468,PHI:8940,UniProt,Q9HZL1,GenBank,AE004724_11,,,PAO1,nqrF (PA2994),,,,,,PHI:8939; PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13469,PHI:8941,UniProt,Q9HZL0,GenBank,AE004724_12,,,PAO1,nqrE (PA2995),,,,,,PHI:8939; PHI:8940; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13470,PHI:8942,UniProt,Q9HZK9,GenBank,AE004724_13,,,PAO1,nqrD (PA2996),,,,,,PHI:8939; PHI:8940; PHI:8941; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13471,PHI:8943,UniProt,Q9HZK8,GenBank,AE004724_14,,,PAO1,nqrC (PA2997),,,,,,PHI:8939; PHI:8940; PHI:8941; PHI:8942; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13472,PHI:8944,UniProt,Q9HZK7,GenBank,AE004724_15,,,PAO1,nqrB (PA2998),,,,,,PHI:8939; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13473,PHI:8945,UniProt,Q9HZK6,GenBank,AE004724_16,,,PAO1,nqrA (PA2999),,,,,,PHI:8939; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13474,PHI:8937,UniProt,Q9I0J4,GenBank,AE004693_3,,,PAO1,nuoI (PA2644),,,,,,PHI:8938; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,NADH-quinone oxidoreductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13475,PHI:8938,UniProt,Q9I0J3,GenBank,AE004693_4,,,PAO1,nuoJ (PA2645),,,,,,PHI:8937; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,NADH-quinone oxidoreductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13476,PHI:8940,UniProt,Q9HZL1,GenBank,AE004724_11,,,PAO1,nqrF (PA2994),,,,,,PHI:8937; PHI:8938; PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13477,PHI:8941,UniProt,Q9HZL0,GenBank,AE004724_12,,,PAO1,nqrE (PA2995),,,,,,PHI:8937; PHI:8938; PHI:8940; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13478,PHI:8942,UniProt,Q9HZK9,GenBank,AE004724_13,,,PAO1,nqrD (PA2996),,,,,,PHI:8937; PHI:8938; PHI:8940; PHI:8941; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13479,PHI:8943,UniProt,Q9HZK8,GenBank,AE004724_14,,,PAO1,nqrC (PA2997),,,,,,PHI:8937; PHI:8938; PHI:8940; PHI:8941; PHI:8942; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13480,PHI:8944,UniProt,Q9HZK7,GenBank,AE004724_15,,,PAO1,nqrB (PA2998),,,,,,PHI:8937; PHI:8938; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13481,PHI:8945,UniProt,Q9HZK6,GenBank,AE004724_16,,,PAO1,nqrA (PA2999),,,,,,PHI:8937; PHI:8938; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In the Galleria mellonella model, neither deletion of NDH1 nor NDH-2 led to a change in median lethal dose, although death occurred more slowly in the NDH-1 deletion infections.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13482,PHI:8939,UniProt,Q9HVN9,GenBank,AE004867_12,,,PAO1,ndh (PA4538),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,NADH dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13483,PHI:8940,UniProt,Q9HZL1,GenBank,AE004724_11,,,PAO1,nqrF (PA2994),,,,,,PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13484,PHI:8941,UniProt,Q9HZL0,GenBank,AE004724_12,,,PAO1,nqrE (PA2995),,,,,,PHI:8940; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13485,PHI:8942,UniProt,Q9HZK9,GenBank,AE004724_13,,,PAO1,nqrD (PA2996),,,,,,PHI:8940; PHI:8941; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13486,PHI:8943,UniProt,Q9HZK8,GenBank,AE004724_14,,,PAO1,nqrC (PA2997),,,,,,PHI:8940; PHI:8941; PHI:8942; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13487,PHI:8944,UniProt,Q9HZK7,GenBank,AE004724_15,,,PAO1,nqrB (PA2998),,,,,,PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13488,PHI:8945,UniProt,Q9HZK6,GenBank,AE004724_16,,,PAO1,nqrA (PA2999),,,,,,PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13489,PHI:8939,UniProt,Q9HVN9,GenBank,AE004867_12,,,PAO1,ndh (PA4538),,,,,,PHI:8937; PHI:8938,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,NADH dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13490,PHI:8937,UniProt,Q9I0J4,GenBank,AE004693_3,,,PAO1,nuoI (PA2644),,,,,,PHI:8939; PHI:8938,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,NADH-quinone oxidoreductase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13491,PHI:8938,UniProt,Q9I0J3,GenBank,AE004693_4,,,PAO1,nuoJ (PA2645),,,,,,PHI:8939; PHI:8937,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,NADH-quinone oxidoreductase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13492,PHI:8939,UniProt,Q9HVN9,GenBank,AE004867_12,,,PAO1,ndh (PA4538),,,,,,PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,NADH dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13493,PHI:8940,UniProt,Q9HZL1,GenBank,AE004724_11,,,PAO1,nqrF (PA2994),,,,,,PHI:8939; PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13494,PHI:8941,UniProt,Q9HZL0,GenBank,AE004724_12,,,PAO1,nqrE (PA2995),,,,,,PHI:8939; PHI:8940; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13495,PHI:8942,UniProt,Q9HZK9,GenBank,AE004724_13,,,PAO1,nqrD (PA2996),,,,,,PHI:8939; PHI:8940; PHI:8941; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13496,PHI:8943,UniProt,Q9HZK8,GenBank,AE004724_14,,,PAO1,nqrC (PA2997),,,,,,PHI:8939; PHI:8940; PHI:8941; PHI:8942; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13497,PHI:8944,UniProt,Q9HZK7,GenBank,AE004724_15,,,PAO1,nqrB (PA2998),,,,,,PHI:8939; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13498,PHI:8945,UniProt,Q9HZK6,GenBank,AE004724_16,,,PAO1,nqrA (PA2999),,,,,,PHI:8939; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13499,PHI:8937,UniProt,Q9I0J4,GenBank,AE004693_3,,,PAO1,nuoI (PA2644),,,,,,PHI:8938; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,NADH-quinone oxidoreductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13500,PHI:8938,UniProt,Q9I0J3,GenBank,AE004693_4,,,PAO1,nuoJ (PA2645),,,,,,PHI:8937; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,NADH-quinone oxidoreductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13501,PHI:8940,UniProt,Q9HZL1,GenBank,AE004724_11,,,PAO1,nqrF (PA2994),,,,,,PHI:8937; PHI:8938; PHI:8941; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13502,PHI:8941,UniProt,Q9HZL0,GenBank,AE004724_12,,,PAO1,nqrE (PA2995),,,,,,PHI:8937; PHI:8938; PHI:8940; PHI:8942; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13503,PHI:8942,UniProt,Q9HZK9,GenBank,AE004724_13,,,PAO1,nqrD (PA2996),,,,,,PHI:8937; PHI:8938; PHI:8940; PHI:8941; PHI:8943; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13504,PHI:8943,UniProt,Q9HZK8,GenBank,AE004724_14,,,PAO1,nqrC (PA2997),,,,,,PHI:8937; PHI:8938; PHI:8940; PHI:8941; PHI:8942; PHI:8944; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13505,PHI:8944,UniProt,Q9HZK7,GenBank,AE004724_15,,,PAO1,nqrB (PA2998),,,,,,PHI:8937; PHI:8938; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8945,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13506,PHI:8945,UniProt,Q9HZK6,GenBank,AE004724_16,,,PAO1,nqrA (PA2999),,,,,,PHI:8937; PHI:8938; PHI:8940; PHI:8941; PHI:8942; PHI:8943; PHI:8944,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,Na(+)-translocating NADH-quinone reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13507,PHI:8937,UniProt,Q9I0J4,GenBank,AE004693_3,,,PAO1,nuoI (PA2644),,,,,,PHI:8938,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,NADH-quinone oxidoreductase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13508,PHI:8938,UniProt,Q9I0J3,GenBank,AE004693_4,,,PAO1,nuoJ (PA2645),,,,,,PHI:8937,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romaine,,,leaf,NADH-quinone oxidoreductase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30804898,PubMed,10.3389/fmicb.2019.00075,Front Microbiol. 2019 Feb 5;10:75,zemkea@upmc.edu,"In a lettuce model of virulence, loss of NDH-1 caused a decrease in recovered viable bacteria and a decrease in visual tissue damage. The compound deletion of NDH-1/NDH-2 causes a severe growth defect, both under aerobic and anaerobic conditions.",A Torres 2019,2019,9 genes,Torres-2019-NADH Dehydrogenases in Pseudomonas,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13509,PHI:8946,,no data found,,,,,,FAZ5,,,,,,,5665,Leishmania mexicana,,MNYC/BZ/62/M379,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,footpad; lymph node,short flagellum attachment zone protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30850532,PubMed,10.1073/pnas.1812462116,Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6351-6360,jsunter@brookes.ac.uk,"FAZ5 deletion did not affect parasite proliferation and differentiation in culture; however, it dramatically reduced parasite proliferation in the sand fly and mouse.",J D Sunter 2019,2019,1 gene,Sunter-2019-Leishmania flagellum attachment zo,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13510,PHI:8946,,no data found,,,,,,FAZ5,,,,,,,5665,Leishmania mexicana,,MNYC/BZ/62/M379,leishmaniasis,flies,7200,Lutzomyia longipalpis (no common name found),,,,gut,short flagellum attachment zone protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30850532,PubMed,10.1073/pnas.1812462116,Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6351-6360,jsunter@brookes.ac.uk,"FAZ5 deletion did not affect parasite proliferation and differentiation in culture; however, it dramatically reduced parasite proliferation in the sand fly and mouse.",J D Sunter 2019,2019,1 gene,Sunter-2019-Leishmania flagellum attachment zo,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13511,PHI:8947,UniProt,Q99SZ7,GenBank,BAB42971,,,N315,vraS,,,,,,,1280,Staphylococcus aureus,,CB5014,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sensor protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30760612,PubMed,10.1128/mSphere.00557-18,mSphere. 2019 Feb 13;4(1). pii: e00557-18,aerosato@houstonmethodist.org,"DAPr CB1634 and CB5014 MRSA strains with vraSR upregulation were less virulent than their susceptible counterparts, CB1631 and CB5013.",A Taglialegna 2019,2019,2 genes,Taglialegna-2019-VraSR and Virulence Trait Mod,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13512,PHI:8948,UniProt,Q7A4R9,GenBank,BAB69827,,,N315,vraR,,,,,,,1280,Staphylococcus aureus,,CB5014,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,response regulator protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30760612,PubMed,10.1128/mSphere.00557-18,mSphere. 2019 Feb 13;4(1). pii: e00557-18,aerosato@houstonmethodist.org,"DAPr CB1634 and CB5014 MRSA strains with vraSR upregulation were less virulent than their susceptible counterparts, CB1631 and CB5013.",A Taglialegna 2019,2019,2 genes,Taglialegna-2019-VraSR and Virulence Trait Mod,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13513,PHI:8947,UniProt,Q99SZ7,GenBank,BAB42971,,,N315,vraS,,,,,,,1280,Staphylococcus aureus,,CB1634,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sensor protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30760612,PubMed,10.1128/mSphere.00557-18,mSphere. 2019 Feb 13;4(1). pii: e00557-18,aerosato@houstonmethodist.org,"DAPr CB1634 and CB5014 MRSA strains with vraSR upregulation were less virulent than their susceptible counterparts, CB1631 and CB5013.",A Taglialegna 2019,2019,2 genes,Taglialegna-2019-VraSR and Virulence Trait Mod,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13514,PHI:8948,UniProt,Q7A4R9,GenBank,BAB69827,,,N315,vraR,,,,,,,1280,Staphylococcus aureus,,CB1634,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,response regulator protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30760612,PubMed,10.1128/mSphere.00557-18,mSphere. 2019 Feb 13;4(1). pii: e00557-18,aerosato@houstonmethodist.org,"DAPr CB1634 and CB5014 MRSA strains with vraSR upregulation were less virulent than their susceptible counterparts, CB1631 and CB5013.",A Taglialegna 2019,2019,2 genes,Taglialegna-2019-VraSR and Virulence Trait Mod,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13515,PHI:8949,,no data found,,,,,,phz,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,phenazine biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30850535,PubMed,10.1073/pnas.1817259116,Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6146-6151,cole.haynes@umassmed.edu,"Host gene alteration data available for bZIP protein ZIP-3. Wild-type worm survival was similar upon exposure to wild type or P. aeruginosa-Δphz, suggesting the associated mitochondrial perturbation did not decrease survival.",P Deng 2019,2019,1 gene,Deng-2019-Mitochondrial UPR repression during,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13516,PHI:8950,,no data found,,,,,,SPI19,,,,,,,28901,Salmonella enterica,594,subsp. enterica serovar Gallinarum strain G9,fowl typhoid,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,type VI secretion system (T6SS),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster; gene complementation,,,YVS,30827393,PubMed,10.1016/j.vetmic.2019.01.006,Vet Microbiol. 2019 Mar;230:23-31,jeo@sund.ku.dk,T6SS encoded from SPI19 had different roles in the two serovars and that it was a virulence-factor after oral challenge of mice in S. Dublin.,C Schroll 2019,2019,1 gene,Schroll-2019-The SPI-19 encoded type-six secre,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13517,PHI:8950,,no data found,,,,,,SPI19,,,,,,,28901,Salmonella enterica,594,subsp. enterica serovar Gallinarum strain G9,fowl typhoid,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,HD-11 cell,type VI secretion system (T6SS),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster; gene complementation,,,YVS,30827393,PubMed,10.1016/j.vetmic.2019.01.006,Vet Microbiol. 2019 Mar;230:23-31,jeo@sund.ku.dk,T6SS encoded from SPI19 had different roles in the two serovars and that it was a virulence-factor after oral challenge of mice in S. Dublin.,C Schroll 2019,2019,1 gene,Schroll-2019-The SPI-19 encoded type-six secre,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13518,PHI:8950,,no data found,,,,,,SPI19,,,,,,,28901,Salmonella enterica,594,subsp. enterica serovar Gallinarum strain G9,fowl typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestine; mouth; spleen,type VI secretion system (T6SS),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster; gene complementation,,,YVS,30827393,PubMed,10.1016/j.vetmic.2019.01.006,Vet Microbiol. 2019 Mar;230:23-31,jeo@sund.ku.dk,T6SS encoded from SPI19 had different roles in the two serovars and that it was a virulence-factor after oral challenge of mice in S. Dublin.,C Schroll 2019,2019,1 gene,Schroll-2019-The SPI-19 encoded type-six secre,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13519,PHI:8950,,no data found,,,,,,SPI19,,,,,,,28901,Salmonella enterica,594,subsp. enterica serovar Gallinarum strain J91,fowl typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestine; mouth; spleen,type VI secretion system (T6SS),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster; gene complementation,,,YVS,30827393,PubMed,10.1016/j.vetmic.2019.01.006,Vet Microbiol. 2019 Mar;230:23-31,jeo@sund.ku.dk,T6SS encoded from SPI19 had different roles in the two serovars and that it was a virulence-factor after oral challenge of mice in S. Dublin.,C Schroll 2019,2019,1 gene,Schroll-2019-The SPI-19 encoded type-six secre,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13520,PHI:8950,,no data found,,,,,,SPI19,,,,,,,28901,Salmonella enterica,98360,subsp. enterica serovar Dublin strain 2229,salmonellosis (cattle),birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,type VI secretion system (T6SS),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster; gene complementation,,,YVS,30827393,PubMed,10.1016/j.vetmic.2019.01.006,Vet Microbiol. 2019 Mar;230:23-31,jeo@sund.ku.dk,T6SS encoded from SPI19 had different roles in the two serovars and that it was a virulence-factor after oral challenge of mice in S. Dublin.,C Schroll 2019,2019,1 gene,Schroll-2019-The SPI-19 encoded type-six secre,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13521,PHI:8950,,no data found,,,,,,SPI19,,,,,,,28901,Salmonella enterica,98360,subsp. enterica serovar Dublin strain 2229,salmonellosis (cattle),rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestine,type VI secretion system (T6SS),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster; gene complementation,,,YVS,30827393,PubMed,10.1016/j.vetmic.2019.01.006,Vet Microbiol. 2019 Mar;230:23-31,jeo@sund.ku.dk,T6SS encoded from SPI19 had different roles in the two serovars and that it was a virulence-factor after oral challenge of mice in S. Dublin.,C Schroll 2019,2019,1 gene,Schroll-2019-The SPI-19 encoded type-six secre,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13522,PHI:8950,,no data found,,,,,,SPI19,,,,,,,28901,Salmonella enterica,98360,subsp. enterica serovar Dublin strain 2229,salmonellosis (cattle),rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,mouth; spleen,type VI secretion system (T6SS),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster; gene complementation,,,YVS,30827393,PubMed,10.1016/j.vetmic.2019.01.006,Vet Microbiol. 2019 Mar;230:23-31,jeo@sund.ku.dk,T6SS encoded from SPI19 had different roles in the two serovars and that it was a virulence-factor after oral challenge of mice in S. Dublin.,C Schroll 2019,2019,1 gene,Schroll-2019-The SPI-19 encoded type-six secre,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13523,PHI:8951,UniProt,B2HJI8,GenBank,ACC38657,,,M,esxB_1 (MMAR_0187),,,,,,,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESAT-6 like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13524,PHI:8952,UniProt,B2HJI5,GenBank,ACC38654,,,M,MMAR_0184,,deletion of extended ESX-6 locus,,,,PHI:8953; PHI:8954; PHI:8951; PHI:8955; PHI:8956; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,conserved hypothetical membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13525,PHI:8953,UniProt,B2HJI6,GenBank,ACC38655,,,M,PE35,,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8954; PHI:8951; PHI:8955; PHI:8956; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,PE family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13526,PHI:8954,UniProt,A0A2Z5Y7Z1,GenBank,BBC63291,,,ATCC 927,PPE68_1,,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8951; PHI:8955; PHI:8956; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,PPE family immunomodulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13527,PHI:8951,UniProt,B2HJI8,GenBank,ACC38657,,,M,esxB_1 (MMAR_0187),,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8955; PHI:8956; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESAT-6 like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13528,PHI:8955,UniProt,B2HJI9,GenBank,ACC38658,,,M,esxA_1 (MMAR_0188),,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8951; PHI:8956; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESAT-6 like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13529,PHI:8956,UniProt,B2HJJ0,GenBank,ACC38659,,,M,esxA_3 (MMAR_0189),,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8951; PHI:8955; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,conserved hypothetical EsxA-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13530,PHI:8957,UniProt,B2HKF6,GenBank,ACC38661,,,M,MMAR_0191,,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8951; PHI:8955; PHI:8956; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,PPE family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13531,PHI:8958,UniProt,B2HKF9,GenBank,ACC38664,,,M,esxB_2 (MMAR_0195),,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8951; PHI:8955; PHI:8956; PHI:8957; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,conserved hypothetical EsxB-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13532,PHI:8959,UniProt,B2HKG0,GenBank,ACC38665,,,M,esxA_2 (MMAR_0196),,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8951; PHI:8955; PHI:8956; PHI:8957; PHI:8958,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,conserved hypothetical EsxA-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13533,PHI:8960,UniProt,B2HJI8,GenBank,ACC43856,,,M,esxB,,,,,,PHI:8961,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESAT-6 like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13534,PHI:8961,UniProt,B2HNQ2,GenBank,ACC43857,,,M,esxA,,,,,,PHI:8960,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESAT-6 like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13535,PHI:8960,UniProt,B2HJI8,GenBank,ACC43856,,,M,esxB,,,,,,PHI:8961; PHI:8951,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESAT-6 like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13536,PHI:8961,UniProt,B2HNQ2,GenBank,ACC43857,,,M,esxA,,,,,,PHI:8960; PHI:8951,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESAT-6 like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13537,PHI:8951,UniProt,B2HJI8,GenBank,ACC38657,,,M,esxB_1 (MMAR_0187),,,,,,PHI:8960; PHI:8961,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESAT-6 like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13538,PHI:8952,UniProt,B2HJI5,GenBank,ACC38654,,,M,MMAR_0184,,deletion of extended ESX-6 locus,,,,PHI:8953; PHI:8954; PHI:8951; PHI:8955; PHI:8956; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,conserved hypothetical membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13539,PHI:8953,UniProt,B2HJI6,GenBank,ACC38655,,,M,PE35,,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8954; PHI:8951; PHI:8955; PHI:8956; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,PE family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13540,PHI:8954,UniProt,A0A2Z5Y7Z1,GenBank,BBC63291,,,ATCC 927,PPE68_1,,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8951; PHI:8955; PHI:8956; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,PPE family immunomodulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13541,PHI:8951,UniProt,B2HJI8,GenBank,ACC38657,,,M,esxB_1 (MMAR_0187),,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8955; PHI:8956; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,ESAT-6 like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13542,PHI:8955,UniProt,B2HJI9,GenBank,ACC38658,,,M,esxA_1 (MMAR_0188),,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8951; PHI:8956; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,ESAT-6 like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13543,PHI:8956,UniProt,B2HJJ0,GenBank,ACC38659,,,M,esxA_3 (MMAR_0189),,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8951; PHI:8955; PHI:8957; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,conserved hypothetical EsxA-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13544,PHI:8957,UniProt,B2HKF6,GenBank,ACC38661,,,M,MMAR_0191,,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8951; PHI:8955; PHI:8956; PHI:8958; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,PPE family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13545,PHI:8958,UniProt,B2HKF9,GenBank,ACC38664,,,M,esxB_2 (MMAR_0195),,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8951; PHI:8955; PHI:8956; PHI:8957; PHI:8959,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,conserved hypothetical EsxB-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13546,PHI:8959,UniProt,B2HKG0,GenBank,ACC38665,,,M,esxA_2 (MMAR_0196),,deletion of extended ESX-6 locus,,,,PHI:8952; PHI:8953; PHI:8954; PHI:8951; PHI:8955; PHI:8956; PHI:8957; PHI:8958,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,conserved hypothetical EsxA-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13547,PHI:8960,UniProt,B2HJI8,GenBank,ACC43856,,,M,esxB,,,,,,PHI:8961,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,ESAT-6 like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13548,PHI:8961,UniProt,B2HNQ2,GenBank,ACC43857,,,M,esxA,,,,,,PHI:8960,1781,Mycobacterium marinum,1348799,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,ESAT-6 like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13549,PHI:8951,UniProt,B2HJI8,GenBank,ACC38657,,,M,esxB_1 (MMAR_0187),,,,,,,1781,Mycobacterium marinum,1348799,M,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,ESAT-6 like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29555701,PubMed,10.1128/JB.00726-17,J Bacteriol. 2018 May 9;200(11). pii: e00726-17,pchampio@nd.edu,EsxB_1 gene and the extended ESX-6 region were not required for ESX-1 secretion or virulence.,R E Bosserman 2018,2018,11 genes,Bosserman-2018-Esx paralogs are functionally e,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13550,PHI:8962,UniProt,B5Y1W2,GenBank,ACI08908,,,342,leuA,,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; bronchoalveolar lavage fluid,2-isopropylmalate synthase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29712730,PubMed,10.1128/IAI.00135-18,Infect Immun. 2018 Jun 21;86(7). pii: e00135-18,mwargo@uvm.edu,BALF collected from mice infected with the leuABCD deletion strain demonstrated a reduction in the neutrophilic response to the mutant strain.,G G Willsey 2018,2018,7 genes,Willsey-2018-Pulmonary surfactant promotes vir,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13551,PHI:8963,UniProt,W9BCN0,GenBank,AIT01852,,,PMK1,leuB,,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; bronchoalveolar lavage fluid,3-isopropylmalate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29712730,PubMed,10.1128/IAI.00135-18,Infect Immun. 2018 Jun 21;86(7). pii: e00135-18,mwargo@uvm.edu,BALF collected from mice infected with the leuABCD deletion strain demonstrated a reduction in the neutrophilic response to the mutant strain.,G G Willsey 2018,2018,7 genes,Willsey-2018-Pulmonary surfactant promotes vir,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13552,PHI:8964,UniProt,W9BBU8,GenBank,AIT01851,,,PMK1,leuC,,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; bronchoalveolar lavage fluid,3-isopropylmalate dehydratase large subunit,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29712730,PubMed,10.1128/IAI.00135-18,Infect Immun. 2018 Jun 21;86(7). pii: e00135-18,mwargo@uvm.edu,BALF collected from mice infected with the leuABCD deletion strain demonstrated a reduction in the neutrophilic response to the mutant strain.,G G Willsey 2018,2018,7 genes,Willsey-2018-Pulmonary surfactant promotes vir,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13553,PHI:8965,UniProt,W9BQ45,GenBank,AIT01850,,,PMK1,leuD,,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; bronchoalveolar lavage fluid,3-isopropylmalate dehydratase small subunit,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29712730,PubMed,10.1128/IAI.00135-18,Infect Immun. 2018 Jun 21;86(7). pii: e00135-18,mwargo@uvm.edu,BALF collected from mice infected with the leuABCD deletion strain demonstrated a reduction in the neutrophilic response to the mutant strain.,G G Willsey 2018,2018,7 genes,Willsey-2018-Pulmonary surfactant promotes vir,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13554,PHI:8966,UniProt,A0A1C1TY69,GenBank,AUY17561,,,KPNIH48,mdtJ,,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; bronchoalveolar lavage fluid,multidrug transporter subunit,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29712730,PubMed,10.1128/IAI.00135-18,Infect Immun. 2018 Jun 21;86(7). pii: e00135-18,mwargo@uvm.edu,"BALF collected from mice infected with KPPR1 ΔmdtJI contained significantly fewer infiltrating leukocytes, neutrophils and macrophages than BALF collected from mice infected with the WT strain.",G G Willsey 2018,2018,7 genes,Willsey-2018-Pulmonary surfactant promotes vir,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13555,PHI:8967,UniProt,B5XR94,GenBank,ACI10803,,,342,mdtI,,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; bronchoalveolar lavage fluid,multidrug resistance protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29712730,PubMed,10.1128/IAI.00135-18,Infect Immun. 2018 Jun 21;86(7). pii: e00135-18,mwargo@uvm.edu,"BALF collected from mice infected with KPPR1 ΔmdtJI contained significantly fewer infiltrating leukocytes, neutrophils and macrophages than BALF collected from mice infected with the WT strain.",G G Willsey 2018,2018,7 genes,Willsey-2018-Pulmonary surfactant promotes vir,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13556,PHI:8968,UniProt,A0A086IQC3,GenBank,AIS99989,,,PMK1,proV,,,,,,,573,Klebsiella pneumoniae,,KPPR1,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; bronchoalveolar lavage fluid,glycine betaine/L-proline transport ATP-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29712730,PubMed,10.1128/IAI.00135-18,Infect Immun. 2018 Jun 21;86(7). pii: e00135-18,mwargo@uvm.edu,BALF collected from these mice indicated that deletion of proV altered polymorphonuclear leukocyte (PMN) recruitment.,G G Willsey 2018,2018,7 genes,Willsey-2018-Pulmonary surfactant promotes vir,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13557,PHI:8969,UniProt,J9VQ04,GenBank,AFR95476,,,H99,bta1 (CNAG_02353),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; blood; brain,betaine lipid synthase,,,phosphate sensing and acquisition (PHO) pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30789965,PubMed,10.1371/journal.pone.0212651,PLoS One. 2019 Feb 21;14(2):e0212651,julianne.djordjevic@sydney.edu.au,Bta1Δ tolerated alkaline pH and disseminated to the brain.,S Lev 2019,2019,1 gene,Lev-2019-The PHO signaling pathway directs lip,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13558,PHI:8970,UniProt,P83776,GenBank,AOW31187,,,SC5314,Cahxk2,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical hexokinase,,,,reduced virulence,,,,,,,,reduced,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full; gene complementation,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13559,PHI:8970,UniProt,P83776,GenBank,AOW31187,,,SC5314,Cahxk2,chromosome R,,,,,PHI:8971,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical hexokinase,,,,reduced virulence,,,,,,,,reduced,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13560,PHI:8971,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,Caglk1,chromosome R,,,,,PHI:8970,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical glucokinase,,,,reduced virulence,,,,,,,,reduced,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13561,PHI:8971,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,Caglk1,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical glucokinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13562,PHI:8971,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,Caglk1,chromosome R,,,,,PHI:8972,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical glucokinase,,,,reduced virulence,,,,,,,,wild type,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13563,PHI:8972,UniProt,Q59RR7,GenBank,AOW31442,,,SC5314,Caglk4,chromosome R,,,,,PHI:8971,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical glucokinase,,,,reduced virulence,,,,,,,,wild type,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13564,PHI:8970,UniProt,P83776,GenBank,AOW31187,,,SC5314,Cahxk2,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hypothetical hexokinase,,,,reduced virulence,,,,,,,,reduced,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full; gene complementation,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13565,PHI:8970,UniProt,P83776,GenBank,AOW31187,,,SC5314,Cahxk2,chromosome R,,,,,PHI:8971,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hypothetical hexokinase,,,,reduced virulence,,,,,,,,reduced,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13566,PHI:8971,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,Caglk1,chromosome R,,,,,PHI:8970,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hypothetical glucokinase,,,,reduced virulence,,,,,,,,reduced,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13567,PHI:8971,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,Caglk1,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hypothetical glucokinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13568,PHI:8971,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,Caglk1,chromosome R,,,,,PHI:8972,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hypothetical glucokinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13569,PHI:8972,UniProt,Q59RR7,GenBank,AOW31442,,,SC5314,Caglk4,chromosome R,,,,,PHI:8971,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,hypothetical glucokinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,KCl; H2O2; SDS; caffeine,KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full,,,YVS,30858840,PubMed,10.3389/fmicb.2019.00327,Front Microbiol. 2019 Feb 25;10:327,pascale.cotton@univ-lyon1.fr,"Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing by C. albicans.",R Laurian 2019,2019,3 genes,Laurian-2019-Hexokinase and Glucokinases Are E,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13570,PHI:8973,UniProt,A0A0K0GJS5,,,,,,PXO_RS08445,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13571,PHI:8974,UniProt,A0A0K0GJF6,,,,,,PXO_RS08330,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13572,PHI:8975,UniProt,A0A0K0GJK9,GenBank,ACD58392,,,PXO99A,PXO_RS08270 (RpfG),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13573,PHI:8976,UniProt,A0A0K0GJ33,,,,,,PXO_RS07450,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13574,PHI:8977,UniProt,A0A0K0GJS7,,,,,,PXO_RS09090,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13575,PHI:8978,UniProt,A0A0K0GJQ2,,,,,,PXO_RS08775,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13576,PHI:8979,UniProt,A0A0K0GKL7,,,,,,PXO_RS10565,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,hybrid protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13577,PHI:8980,UniProt,A0A0K0GKB7,,,,,,PXO_RS10155,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13578,PHI:8981,UniProt,A0A0K0GKJ8,,,,,,PXO_RS11120,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13579,PHI:8982,UniProt,A0A0K0GL01,,,,,,PXO_RS11220,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13580,PHI:8983,UniProt,A0A0J9WX31,,,,,,PXO_RS12150/ PXO_RS13080,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13581,PHI:8984,UniProt,A0A0J9WXH2,,,,,,PXO_RS11975/ PXO_RS12905,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13582,PHI:8985,UniProt,A0A0J9WWX5,,,,,,PXO_RS11880/ PXO_RS12810,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13583,PHI:8986,UniProt,A0A0J9WWX0,,,,,,PXO_RS11855/ PXO_RS12785,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13584,PHI:8987,UniProt,A0A0K0GME1,,,,,,PXO_RS15740,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,hybrid protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13585,PHI:8988,UniProt,A0A0K0GM14,,,,,,PXO_RS15395,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13586,PHI:8989,UniProt,A0A0K0GM26,,,,,,PXO_RS15100,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13587,PHI:8990,UniProt,A0A0K0GLZ9,,,,,,PXO_RS14975,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13588,PHI:8991,UniProt,A0A0K0GLV1,,,,,,PXO_RS14970,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13589,PHI:8992,UniProt,A0A0K0GLN5,,,,,,PXO_RS14605,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,hybrid protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13590,PHI:8993,UniProt,A0A0K0GLS1,,,,,,PXO_RS14600,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,hybrid protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13591,PHI:8994,UniProt,A0A0K0GL88,,,,,,PXO_RS14595,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,hybrid protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13592,PHI:8995,UniProt,A0A0K0GLP3,,,,,,PXO_RS14460,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13593,PHI:8996,UniProt,A0A0K0GN07,GenBank,ACD60420,,,PXO99A,PXO_RS18055 (HrpG),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13594,PHI:8997,UniProt,A0A0K0GP04,,,,,,PXO_RS19035,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13595,PHI:8998,UniProt,A0A0K0GP68,,,,,,PXO_RS19400,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13596,PHI:8999,UniProt,Q5H3W2,GenBank,AAW74359,,,KACC10331,PXO_RS19415,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13597,PHI:9000,UniProt,A0A0K0GNX3,GenBank,ACD60781,,,PXO99A,PXO_RS19870,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13598,PHI:9001,UniProt,A0A0K0GPN6,,,,,,PXO_RS20355,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13599,PHI:9002,UniProt,A0A0K0GPS7,,,,,,PXO_RS20535,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13600,PHI:9003,UniProt,A0A0K0GR43,,,,,,PXO_RS23080,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,hybrid protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13601,PHI:9004,UniProt,A0A0K0GQ67,,,,,,PXO_RS22160,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13602,PHI:9005,UniProt,A0A0K0GQR9,,,,,,PXO_RS21800,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13603,PHI:9006,UniProt,A0A0K0GQF3,,,,,,PXO_RS21790,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13604,PHI:9007,,no data found,,,,,,PXO_RS21740,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13605,PHI:9008,UniProt,A0A0K0GQF6,,,,,,PXO_RS21605,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13606,PHI:9009,UniProt,A0A0K0GQL3,,,,,,PXO_RS21535 (StoS),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,hybrid protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13607,PHI:9010,UniProt,A0A0K0GRC2,,,,,,PXO_RS23555,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13608,PHI:9011,UniProt,A0A0K0GFV0,,,,,,PXO_RS01340,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13609,PHI:9012,UniProt,A0A0K0GGA9,,,,,,PXO_RS02255,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13610,PHI:9013,UniProt,A0A0K0GGA9,,,,,,PXO_RS02040,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13611,PHI:9014,UniProt,A0A0K0GGF6,,,,,,PXO_RS02690,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13612,PHI:9015,UniProt,A0A0K0GH16,,,,,,PXO_RS03980,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13613,PHI:9016,UniProt,A0A0K0GHK1,,,,,,PXO_RS04300,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13614,PHI:9017,UniProt,A0A0K0GHK1,,,,,,PXO_RS04305,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,hybrid protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13615,PHI:9018,UniProt,A0A0K0GHP2,,,,,,PXO_RS04760,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13616,PHI:9019,UniProt,A0A0K0GHI2,,,,,,PXO_RS04595,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13617,PHI:9020,UniProt,A0A0K0GI78,,,,,,PXO_RS06090,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13618,PHI:9021,UniProt,A0A0K0GHV7,,,,,,PXO_RS05400,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13619,PHI:9022,UniProt,A0A0K0GIA5,,,,,,PXO_RS05395,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13620,PHI:9023,UniProt,A0A0K0GI30,,,,,,PXO_RS05125 (DetR),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13621,PHI:9024,UniProt,A0A0K0GIC0,,,,,,PXO_RS06365,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13622,PHI:9025,UniProt,A0A0K0GI67,,,,,,PXO_RS06355,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13623,PHI:9026,UniProt,A0A0K0GIX3,,,,,,PXO_RS06785,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13624,PHI:9027,UniProt,A0A0K0GIH5,,,,,,PXO_RS06935,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30828283,PubMed,10.5423/PPJ.NT.09.2018.0193,Plant Pathol J. 2019 Feb;35(1):84-89,swlee6803@khu.ac.kr,Virulence of the 55 mutant strains was examined on leaves of Dong-jin rice plants of which lesion lengths on leaves of 9 mutant strains were significantly reduced compared to other mutants and PXO99A.,S W Han 2019,2019,55 genes,Han-2019-Genome-wide Screening to Identify Res,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13625,PHI:9028,UniProt,P16154,GenBank,CAA63564,,,VPI10463,TcdA,,,,,,,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon; cecum,exotoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30510170,PubMed,10.1038/s41564-018-0300-x,Nat Microbiol. 2019 Feb;4(2):269-279,xchen1@bidmc.harvard.edu,Increased colonic vascular permeability in CDI mice and elevated vascular endothelial growth factor A (VEGF-A) was induced in vivo by infection with TcdA- and/or TcdB-producing C. difficile strains but not with a TcdA-TcdB- isogenic mutant.,J Huang 2018,2018,2 genes,Huang-2018-Clostridium difficile toxins induce,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13626,PHI:9029,UniProt,P18177,GenBank,CAA63562,,,VPI10463,TcdB,,,,,,,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon; cecum,exotoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30510170,PubMed,10.1038/s41564-018-0300-x,Nat Microbiol. 2019 Feb;4(2):269-279,xchen1@bidmc.harvard.edu,Increased colonic vascular permeability in CDI mice and elevated vascular endothelial growth factor A (VEGF-A) was induced in vivo by infection with TcdA- and/or TcdB-producing C. difficile strains but not with a TcdA-TcdB- isogenic mutant.,J Huang 2018,2018,2 genes,Huang-2018-Clostridium difficile toxins induce,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13627,PHI:9028,UniProt,P16154,GenBank,CAA63564,,,VPI10463,TcdA,,,,,,PHI:9029,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon; cecum,exotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30510170,PubMed,10.1038/s41564-018-0300-x,Nat Microbiol. 2019 Feb;4(2):269-279,xchen1@bidmc.harvard.edu,Increased colonic vascular permeability in CDI mice and elevated vascular endothelial growth factor A (VEGF-A) was induced in vivo by infection with TcdA- and/or TcdB-producing C. difficile strains but not with a TcdA-TcdB- isogenic mutant.,J Huang 2018,2018,2 genes,Huang-2018-Clostridium difficile toxins induce,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13628,PHI:9029,UniProt,P18177,GenBank,CAA63562,,,VPI10463,TcdB,,,,,,PHI:9028,1496,Clostridioides difficile,,M7404,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon; cecum,exotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30510170,PubMed,10.1038/s41564-018-0300-x,Nat Microbiol. 2019 Feb;4(2):269-279,xchen1@bidmc.harvard.edu,Increased colonic vascular permeability in CDI mice and elevated vascular endothelial growth factor A (VEGF-A) was induced in vivo by infection with TcdA- and/or TcdB-producing C. difficile strains but not with a TcdA-TcdB- isogenic mutant.,J Huang 2018,2018,2 genes,Huang-2018-Clostridium difficile toxins induce,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13629,PHI:9030,,no data found,,,,,,mapZ,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,chemotaxis methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30804897,PubMed,10.3389/fmicb.2019.00067,Front Microbiol. 2019 Feb 5;10:67,xulinghui@scau.edu.cn,Chemotaxis assays showed that overexpression of MapZ hampered the taxis of P. aeruginosa toward chemoattractants and scratch-wounded human cells.,S Sheng 2019,2019,2 genes,Sheng-2019-The MapZ-Mediated Methylation of Ch,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13630,PHI:9030,,no data found,,,,,,mapZ,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver,chemotaxis methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30804897,PubMed,10.3389/fmicb.2019.00067,Front Microbiol. 2019 Feb 5;10:67,xulinghui@scau.edu.cn,Chemotaxis assays showed that overexpression of MapZ hampered the taxis of P. aeruginosa toward chemoattractants and scratch-wounded human cells.,S Sheng 2019,2019,2 genes,Sheng-2019-The MapZ-Mediated Methylation of Ch,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13631,PHI:9031,UniProt,O87131,,,,,,cheR1,,D144A-Y222A,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver,c-di-GMP-binding adaptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30804897,PubMed,10.3389/fmicb.2019.00067,Front Microbiol. 2019 Feb 5;10:67,xulinghui@scau.edu.cn,Chemotaxis assays showed that overexpression of MapZ hampered the taxis of P. aeruginosa toward chemoattractants and scratch-wounded human cells.,S Sheng 2019,2019,2 genes,Sheng-2019-The MapZ-Mediated Methylation of Ch,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13632,PHI:9032,UniProt,G4N7K8,GenBank,EHA50865,,,70-15,Mocrn1 (MGG_06389),chromosome 4,,,MoRGS7 (MGG_11693); MoMagA (MGG_01818); MoCAP1(MGG_01722),UniProt: G4NF12; GenBank: EHA49531; UniProt: G4MW64; GenBank: EHA55024; UniProt: G4MV90; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,coronin,,,,reduced virulence,,yes,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30802274,PubMed,10.1371/journal.ppat.1007382,PLoS Pathog. 2019 Feb 25;15(2):e1007382,zhgzhang@njau.edu.cn,MoCrn1 was involved in appressorium development and pathogenicity through regulating intracellular cAMP levels.,X Li 2019,2019,2 genes,Li-2019-The seven transmembrane domain protein,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13633,PHI:9032,UniProt,G4N7K8,GenBank,EHA50865,,,70-15,Mocrn1 (MGG_06389),chromosome 4,,,MoRGS7 (MGG_11693); MoMagA (MGG_01818); MoCAP1(MGG_01722),UniProt: G4NF12; GenBank: EHA49531; UniProt: G4MW64; GenBank: EHA55024; UniProt: G4MV90; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,coronin,,,,reduced virulence,,yes,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30802274,PubMed,10.1371/journal.ppat.1007382,PLoS Pathog. 2019 Feb 25;15(2):e1007382,zhgzhang@njau.edu.cn,MoCrn1 was involved in appressorium development and pathogenicity through regulating intracellular cAMP levels.,X Li 2019,2019,2 genes,Li-2019-The seven transmembrane domain protein,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13634,PHI:9032,UniProt,G4N7K8,GenBank,EHA50865,,,70-15,Mocrn1 (MGG_06389),chromosome 4,,,MoRGS7 (MGG_11693); MoMagA (MGG_01818); MoCAP1(MGG_01722),UniProt: G4NF12; GenBank: EHA49531; UniProt: G4MW64; GenBank: EHA55024; UniProt: G4MV90; Gen,PHI:9033,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,coronin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30802274,PubMed,10.1371/journal.ppat.1007382,PLoS Pathog. 2019 Feb 25;15(2):e1007382,zhgzhang@njau.edu.cn,MoCrn1 was involved in appressorium development and pathogenicity through regulating intracellular cAMP levels.,X Li 2019,2019,2 genes,Li-2019-The seven transmembrane domain protein,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13635,PHI:9033,UniProt,G4MW64,GenBank,EHA55024,,,70-15,MoMagA (MGG_01818),chromosome 2,G187S,,MoRGS7 (MGG_11693); MoCRN1 (MGG_06389); MoCAP1(MGG_01722),UniProt: G4NF12; GenBank: EHA49531; UniProt: G4N7K8; GenBank: EHA50865; UniProt: G4MV90; Gen,PHI:9032,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,guanine nucleotide-binding protein alpha-3 subunit,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30802274,PubMed,10.1371/journal.ppat.1007382,PLoS Pathog. 2019 Feb 25;15(2):e1007382,zhgzhang@njau.edu.cn,MoCrn1 was involved in appressorium development and pathogenicity through regulating intracellular cAMP levels.,X Li 2019,2019,2 genes,Li-2019-The seven transmembrane domain protein,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13636,PHI:9034,,no data found,,,,,,mntE,,mntE::Tn,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,kidney; heart,Mn exporter,,,,reduced virulence,,,,,,,,reduced,,no,sodium hypochlorite; paraquat,sodium hypochlorite: CHEBI:32146; paraquat: CHEBI:34905,,,,,gene mutation,,,YVS,30808698,PubMed,10.1128/mBio.02915-18,MBio. 2019 Feb 26;10(1). pii: e02915-18,eric.skaar@vumc.org,"Strains inactivated for mntE were more sensitive to the oxidants NaOCl and paraquat, indicating Mn homeostasis was critical for resisting oxidative stress.",C M Grunenwald 2019,2019,2 genes,Grunenwald-2019-Manganese Detoxification by Mn,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13637,PHI:9034,,no data found,,,,,,mntE,,mntE::Tn ΔmntR,,,,PHI:9035,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,kidney; heart,Mn exporter,,,,reduced virulence,,,,,,,,reduced,,no,sodium hypochlorite; paraquat,sodium hypochlorite: CHEBI:32146; paraquat: CHEBI:34905,,,,,gene mutation,,,YVS,30808698,PubMed,10.1128/mBio.02915-18,MBio. 2019 Feb 26;10(1). pii: e02915-18,eric.skaar@vumc.org,"Strains inactivated for mntE were more sensitive to the oxidants NaOCl and paraquat, indicating Mn homeostasis was critical for resisting oxidative stress.",C M Grunenwald 2019,2019,2 genes,Grunenwald-2019-Manganese Detoxification by Mn,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13638,PHI:9035,UniProt,Q99VY1,GenBank,AF452622_1,,,8325-4,mntR,,mntE::Tn ΔmntR,,,,PHI:9034,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,kidney; heart,transcriptional repressor,,,,reduced virulence,,,,,,,,reduced,,no,sodium hypochlorite; paraquat,sodium hypochlorite: CHEBI:32146; paraquat: CHEBI:34905,,,,,gene mutation,,,YVS,30808698,PubMed,10.1128/mBio.02915-18,MBio. 2019 Feb 26;10(1). pii: e02915-18,eric.skaar@vumc.org,"Strains inactivated for mntE were more sensitive to the oxidants NaOCl and paraquat, indicating Mn homeostasis was critical for resisting oxidative stress.",C M Grunenwald 2019,2019,2 genes,Grunenwald-2019-Manganese Detoxification by Mn,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13639,PHI:9034,,no data found,,,,,,mntE,,mntE::Tn,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,liver,Mn exporter,,,,reduced virulence,,,,,,,,reduced,,no,sodium hypochlorite; paraquat,sodium hypochlorite: CHEBI:32146; paraquat: CHEBI:34905,,,,,gene mutation,,,YVS,30808698,PubMed,10.1128/mBio.02915-18,MBio. 2019 Feb 26;10(1). pii: e02915-18,eric.skaar@vumc.org,"Strains inactivated for mntE were more sensitive to the oxidants NaOCl and paraquat, indicating Mn homeostasis was critical for resisting oxidative stress.",C M Grunenwald 2019,2019,2 genes,Grunenwald-2019-Manganese Detoxification by Mn,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13640,PHI:9034,,no data found,,,,,,mntE,,mntE::Tn ΔmntR,,,,PHI:9035,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,liver,Mn exporter,,,,reduced virulence,,,,,,,,reduced,,no,sodium hypochlorite; paraquat,sodium hypochlorite: CHEBI:32146; paraquat: CHEBI:34905,,,,,gene mutation,,,YVS,30808698,PubMed,10.1128/mBio.02915-18,MBio. 2019 Feb 26;10(1). pii: e02915-18,eric.skaar@vumc.org,"Strains inactivated for mntE were more sensitive to the oxidants NaOCl and paraquat, indicating Mn homeostasis was critical for resisting oxidative stress.",C M Grunenwald 2019,2019,2 genes,Grunenwald-2019-Manganese Detoxification by Mn,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13641,PHI:9035,UniProt,Q99VY1,GenBank,AF452622_1,,,8325-4,mntR,,mntE::Tn ΔmntR,,,,PHI:9034,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,liver,transcriptional repressor,,,,reduced virulence,,,,,,,,reduced,,no,sodium hypochlorite; paraquat,sodium hypochlorite: CHEBI:32146; paraquat: CHEBI:34905,,,,,gene mutation,,,YVS,30808698,PubMed,10.1128/mBio.02915-18,MBio. 2019 Feb 26;10(1). pii: e02915-18,eric.skaar@vumc.org,"Strains inactivated for mntE were more sensitive to the oxidants NaOCl and paraquat, indicating Mn homeostasis was critical for resisting oxidative stress.",C M Grunenwald 2019,2019,2 genes,Grunenwald-2019-Manganese Detoxification by Mn,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13642,PHI:9035,UniProt,Q99VY1,GenBank,AF452622_1,,,8325-4,mntR,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,kidney; heart; liver,transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,sodium hypochlorite; paraquat,sodium hypochlorite: CHEBI:32146; paraquat: CHEBI:34905,,,,,gene mutation,,,YVS,30808698,PubMed,10.1128/mBio.02915-18,MBio. 2019 Feb 26;10(1). pii: e02915-18,eric.skaar@vumc.org,"Strains inactivated for mntE were more sensitive to the oxidants NaOCl and paraquat, indicating Mn homeostasis was critical for resisting oxidative stress.",C M Grunenwald 2019,2019,2 genes,Grunenwald-2019-Manganese Detoxification by Mn,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13643,PHI:9036,UniProt,I1S2J9,GenBank,XP_011325375,,,PH-1; NRRL 31084,fgm5 (FGSG_10995),chromosome 3,,,,,PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043; PHI:9044; PHI:9045,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,ABC transporter,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13644,PHI:9037,UniProt,I1S2J8,GenBank,CEF88559,,,PH-1,fgm4 (FGSG_10994),chromosome 3,,,,,PHI:9036; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043; PHI:9044; PHI:9045,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,protein containing ankyrin repeats,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13645,PHI:9038,UniProt,I1S2J7,GenBank,XP_011325377,,,PH-1; NRRL 31084,fgm3 (FGSG_10993),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043; PHI:9044; PHI:9045,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,aspartate aminotransferase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13646,PHI:9039,UniProt,I1S2J6,GenBank,CEF88824,,,PH-1,fgm2 (FGSG_10992),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9040; PHI:9041; PHI:9042; PHI:9043; PHI:9044; PHI:9045,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,deacetylase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13647,PHI:9040,UniProt,I1S2J5,GenBank,CEF86137,,,PH-1,fgm1 (FGSG_10991),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9041; PHI:9042; PHI:9043; PHI:9044; PHI:9045,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,cytochrome P450,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13648,PHI:9041,UniProt,I1S2J3,GenBank,CEF87006,,,PH-1,fgm9 (FGSG_10989),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9042; PHI:9043; PHI:9044; PHI:9045,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13649,PHI:9042,UniProt,I1SAJ7,GenBank,CEF87111,,,PH-1,nrps5 (FGSG_13878),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9043; PHI:9044; PHI:9045,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,non-ribosomal peptide synthetase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13650,PHI:9043,UniProt,I1S2J4,GenBank,CEF88261,,,PH-1,nrps9 (FGSG_10990),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9044; PHI:9045,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,non-ribosomal peptide synthetase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13651,PHI:9044,UniProt,I1S2K0,GenBank,CEF87546,,,PH-1,FGSG_10996,chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043; PHI:9045,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13652,PHI:9045,UniProt,I1SAJ8,GenBank,CEF87887,,,PH-1,FGSG_13879,chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043; PHI:9044,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13653,PHI:9036,UniProt,I1S2J9,GenBank,XP_011325375,,,PH-1; NRRL 31084,fgm5 (FGSG_10995),chromosome 3,,,,,PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,ABC transporter,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13654,PHI:9037,UniProt,I1S2J8,GenBank,CEF88559,,,PH-1,fgm4 (FGSG_10994),chromosome 3,,,,,PHI:9036; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,protein containing ankyrin repeats,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13655,PHI:9038,UniProt,I1S2J7,GenBank,XP_011325377,,,PH-1; NRRL 31084,fgm3 (FGSG_10993),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,aspartate aminotransferase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13656,PHI:9039,UniProt,I1S2J6,GenBank,CEF88824,,,PH-1,fgm2 (FGSG_10992),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9040; PHI:9041; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,deacetylase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13657,PHI:9040,UniProt,I1S2J5,GenBank,CEF86137,,,PH-1,fgm1 (FGSG_10991),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9041; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,cytochrome P450,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13658,PHI:9041,UniProt,I1S2J3,GenBank,CEF87006,,,PH-1,fgm9 (FGSG_10989),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13659,PHI:9042,UniProt,I1SAJ7,GenBank,CEF87111,,,PH-1,nrps5 (FGSG_13878),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,non-ribosomal peptide synthetase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13660,PHI:9043,UniProt,I1S2J4,GenBank,CEF88261,,,PH-1,nrps9 (FGSG_10990),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,non-ribosomal peptide synthetase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13661,PHI:9036,UniProt,I1S2J9,GenBank,XP_011325375,,,PH-1; NRRL 31084,fgm5 (FGSG_10995),chromosome 3,,,,,PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,ABC transporter,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13662,PHI:9037,UniProt,I1S2J8,GenBank,CEF88559,,,PH-1,fgm4 (FGSG_10994),chromosome 3,,,,,PHI:9036; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,protein containing ankyrin repeats,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13663,PHI:9038,UniProt,I1S2J7,GenBank,XP_011325377,,,PH-1; NRRL 31084,fgm3 (FGSG_10993),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9039; PHI:9040; PHI:9041; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,aspartate aminotransferase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13664,PHI:9039,UniProt,I1S2J6,GenBank,CEF88824,,,PH-1,fgm2 (FGSG_10992),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9040; PHI:9041; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,deacetylase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13665,PHI:9040,UniProt,I1S2J5,GenBank,CEF86137,,,PH-1,fgm1 (FGSG_10991),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9041; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,cytochrome P450,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13666,PHI:9041,UniProt,I1S2J3,GenBank,CEF87006,,,PH-1,fgm9 (FGSG_10989),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9042; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13667,PHI:9042,UniProt,I1SAJ7,GenBank,CEF87111,,,PH-1,nrps5 (FGSG_13878),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9043,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,non-ribosomal peptide synthetase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13668,PHI:9043,UniProt,I1S2J4,GenBank,CEF88261,,,PH-1,nrps9 (FGSG_10990),chromosome 3,,,,,PHI:9036; PHI:9037; PHI:9038; PHI:9039; PHI:9040; PHI:9041; PHI:9042,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spikelet; coleoptile,non-ribosomal peptide synthetase,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13669,PHI:9037,UniProt,I1S2J8,GenBank,CEF88559,,,PH-1,fgm4 (FGSG_10994),chromosome 3,,,,,PHI:9040; PHI:9041,5518,Fusarium graminearum,229533,PH-1,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,corn silk,protein containing ankyrin repeats,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13670,PHI:9040,UniProt,I1S2J5,GenBank,CEF86137,,,PH-1,fgm1 (FGSG_10991),chromosome 3,,,,,PHI:9037; PHI:9041,5518,Fusarium graminearum,229533,PH-1,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,corn silk,cytochrome P450,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13671,PHI:9041,UniProt,I1S2J3,GenBank,CEF87006,,,PH-1,fgm9 (FGSG_10989),chromosome 3,,,,,PHI:9037; PHI:9040,5518,Fusarium graminearum,229533,PH-1,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,corn silk,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,"hydrogen peroxide; 2,2'-dipyridyl","hydrogen peroxide: CHEBI:16240; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,30804501,PubMed,10.1038/s41467-019-08726-9,Nat Commun. 2019 Feb 25;10(1):922,whtang@sibs.ac.cn,"Fusaoctaxin A, an octapeptide product of NRPS5 and NRPS9 was capable of complementing the deficiency of the mutant FGΔfg3_54 during cell-to-cell invasion and suppressing host defense in wheat infection.",L J Jia 2019,2019,10 genes,Jia-2019-A linear nonribosomal octapeptide fro,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13672,PHI:9046,UniProt,J5JFS1,GenBank,EJP62461,,,ARSEF 2860,BbATG7 (BBA_08545),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,E1-like activating enzyme,,,,reduced virulence,,,,,,reduced,,reduced,,no,menadione; Congo red; sorbitol; sodium chloride; hydrogen peroxide,menadione: CHEBI:28869; Congo red: CHEBI:34653; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30879087,PubMed,10.1007/s00294-019-00955-1,Curr Genet. 2019 Mar 16,yingsh@zju.edu.cn,Ablation of BbATG7 gene blocked the autophagic process under starvation stress.,H Y Lin 2019,2019,1 gene,Lin-2019-Autophagy-related gene ATG7 participa,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13673,PHI:9047,UniProt,I1RBE8,GenBank,XP_011316593,,,PH-1; NRRL 31084,FgPah1 (FGSG_00866),chromosome 1,,,FgSpo7,UniProt: I1RM32; GenBank: CEF87495,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,inflorescence; leaf,phosphatidate phosphatase,,,lipid droplet biosynthesis,reduced virulence,,,,,,,reduced,reduced,,no,H2O2; SDS; Congo red; paraquat; rapamycin,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905; rapamycin: CHEBI:9168,,,,,gene deletion: full; gene complementation,,,YVS,30767239,PubMed,10.1111/nph.15748,New Phytol. 2019 Feb 14,chenyun0927@zju.edu.cn,"LD biogenesis regulated by FgNem1/Spo7-FgPah1 cascade played critical roles in vegetative growth, sexual development and virulence in F. graminearum.",N Liu 2019,2019,3 genes,Liu-2019-Lipid droplet biogenesis regulated by,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13674,PHI:9048,UniProt,I1RM32,GenBank,CEF87495,,,PH-1,FgSpo7 (FGSG_05009),chromosome 3,,,FgPah1; FgNem1,UniProt: I1RBE8; GenBank: XP_011316593; UniProt: I1S0R5; GenBank: CEF75690,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,inflorescence; leaf,protein phosphatase,,,lipid droplet biosynthesis,reduced virulence,,,,,,,reduced,reduced,,no,H2O2; SDS; Congo red; paraquat; rapamycin,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905; rapamycin: CHEBI:9168,,,,,gene deletion: full; gene complementation,,,YVS,30767239,PubMed,10.1111/nph.15748,New Phytol. 2019 Feb 14,chenyun0927@zju.edu.cn,"LD biogenesis regulated by FgNem1/Spo7-FgPah1 cascade played critical roles in vegetative growth, sexual development and virulence in F. graminearum.",N Liu 2019,2019,3 genes,Liu-2019-Lipid droplet biogenesis regulated by,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13675,PHI:9049,UniProt,I1S0R5,GenBank,CEF75690,,,PH-1,FgNem1 (FGSG_10302),chromosome 1,,,FgSpo7,UniProt: I1RM32; GenBank: CEF87495,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,inflorescence; leaf,protein phosphatase,,,lipid droplet biosynthesis,reduced virulence,,,,,,,reduced,reduced,,no,H2O2; SDS; Congo red; paraquat; rapamycin,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905; rapamycin: CHEBI:9168,,,,,gene deletion: full; gene complementation,,,YVS,30767239,PubMed,10.1111/nph.15748,New Phytol. 2019 Feb 14,chenyun0927@zju.edu.cn,"LD biogenesis regulated by FgNem1/Spo7-FgPah1 cascade played critical roles in vegetative growth, sexual development and virulence in F. graminearum.",N Liu 2019,2019,3 genes,Liu-2019-Lipid droplet biogenesis regulated by,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13676,PHI:9047,UniProt,I1RBE8,GenBank,XP_011316593,,,PH-1; NRRL 31084,FgPah1 (FGSG_00866),chromosome 1,,,FgSpo7,UniProt: I1RM32; GenBank: CEF87495,,5518,Fusarium graminearum,229533,PH-1,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,corn silk,phosphatidate phosphatase,,,lipid droplet biosynthesis,reduced virulence,,,,,,,reduced,reduced,,no,H2O2; SDS; Congo red; paraquat; rapamycin,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905; rapamycin: CHEBI:9168,,,,,gene deletion: full; gene complementation,,,YVS,30767239,PubMed,10.1111/nph.15748,New Phytol. 2019 Feb 14,chenyun0927@zju.edu.cn,"LD biogenesis regulated by FgNem1/Spo7-FgPah1 cascade played critical roles in vegetative growth, sexual development and virulence in F. graminearum.",N Liu 2019,2019,3 genes,Liu-2019-Lipid droplet biogenesis regulated by,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13677,PHI:9048,UniProt,I1RM32,GenBank,CEF87495,,,PH-1,FgSpo7 (FGSG_05009),chromosome 3,,,FgPah1; FgNem1,UniProt: I1RBE8; GenBank: XP_011316593; UniProt: I1S0R5; GenBank: CEF75690,,5518,Fusarium graminearum,229533,PH-1,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,corn silk,protein phosphatase,,,lipid droplet biosynthesis,reduced virulence,,,,,,,reduced,reduced,,no,H2O2; SDS; Congo red; paraquat; rapamycin,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905; rapamycin: CHEBI:9168,,,,,gene deletion: full; gene complementation,,,YVS,30767239,PubMed,10.1111/nph.15748,New Phytol. 2019 Feb 14,chenyun0927@zju.edu.cn,"LD biogenesis regulated by FgNem1/Spo7-FgPah1 cascade played critical roles in vegetative growth, sexual development and virulence in F. graminearum.",N Liu 2019,2019,3 genes,Liu-2019-Lipid droplet biogenesis regulated by,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13678,PHI:9049,UniProt,I1S0R5,GenBank,CEF75690,,,PH-1,FgNem1 (FGSG_10302),chromosome 1,,,FgSpo7,UniProt: I1RM32; GenBank: CEF87495,,5518,Fusarium graminearum,229533,PH-1,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,corn silk,protein phosphatase,,,lipid droplet biosynthesis,reduced virulence,,,,,,,reduced,reduced,,no,H2O2; SDS; Congo red; paraquat; rapamycin,H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; paraquat: CHEBI:34905; rapamycin: CHEBI:9168,,,,,gene deletion: full; gene complementation,,,YVS,30767239,PubMed,10.1111/nph.15748,New Phytol. 2019 Feb 14,chenyun0927@zju.edu.cn,"LD biogenesis regulated by FgNem1/Spo7-FgPah1 cascade played critical roles in vegetative growth, sexual development and virulence in F. graminearum.",N Liu 2019,2019,3 genes,Liu-2019-Lipid droplet biogenesis regulated by,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13679,PHI:9050,UniProt,A0A0D2XEI7,GenBank,KNA97769,,,4287,FolVam7 (FOXG_02319),chromosome 5,,,,,,5507,Fusarium oxysporum,660037,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,SNARE protein,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced,,no,NaCl; KCl; sorbitol; Congo red (CR); calcofluor white (CFW); sodium dodecylsulfate (SDS),NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,30848031,PubMed,10.1111/1462-2920.14585,Environ Microbiol. 2019 Mar 7,oysq@yzu.edu.cn,"The ΔFolvam7 mutant was insensitive to salt and osmotic stresses, and hypersensitive to cell wall stressors.",B Li 2019,2019,1 gene,Li-2019-The SNARE protein FolVam7 mediates int,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13680,PHI:9051,UniProt,P9WHZ3,GenBank,CCP45569,,,H37Rv,Rv2770c (PPE44),,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,uncharacterized PPE family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; SDS; diamide,H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,heterologous expression,,,YVS,28743081,PubMed,10.1016/j.intimp.2017.06.028,Int Immunopharmacol. 2017 Sep;50:319-329,georgex@swu.edu.cn,"The Rv2770c could enhance M. smegmatis survival within macrophages and under stresses such as H2O2, SDS, diamide exposure, and low pH condition.",Z Yu 2017,2017,1 gene,Yu-2017-Mycobacterium tuberculosis PPE44 (Rv27,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13681,PHI:9051,UniProt,P9WHZ3,GenBank,CCP45569,,,H37Rv,Rv2770c (PPE44),,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,uncharacterized PPE family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; SDS; diamide,H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,heterologous expression,,,YVS,28743081,PubMed,10.1016/j.intimp.2017.06.028,Int Immunopharmacol. 2017 Sep;50:319-329,georgex@swu.edu.cn,"The Rv2770c could enhance M. smegmatis survival within macrophages and under stresses such as H2O2, SDS, diamide exposure, and low pH condition.",Z Yu 2017,2017,1 gene,Yu-2017-Mycobacterium tuberculosis PPE44 (Rv27,BATCH_091B,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13682,PHI:9052,UniProt,Q63K74,GenBank,CAH38964,,,K96243,BimC (bpss1491),chromosome 2,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774A.1 cell,putative glycosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30968000,PubMed,10.3389/fcimb.2019.00063,Front Cell Infect Microbiol. 2019; 9: 63,jo.stevens@roslin.ed.ac.uk,"The bimC mutant was defective in cell to cell spread as demonstrated by ablation of plaque formation in HeLa cells, and by the inability to form multi-nucleated giant cells in J774.1 cells.",V Srinon 2019,2019,2 genes,Srinon-2019-Burkholderia pseudomallei BimC Is,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13683,PHI:9052,UniProt,Q63K74,GenBank,CAH38964,,,K96243,BimC (bpss1491),chromosome 2,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,macrophage,putative glycosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30968000,PubMed,10.3389/fcimb.2019.00063,Front Cell Infect Microbiol. 2019; 9: 63,jo.stevens@roslin.ed.ac.uk,"The bimC mutant was defective in cell to cell spread as demonstrated by ablation of plaque formation in HeLa cells, and by the inability to form multi-nucleated giant cells in J774.1 cells.",V Srinon 2019,2019,2 genes,Srinon-2019-Burkholderia pseudomallei BimC Is,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13684,PHI:9052,UniProt,Q63K74,GenBank,CAH38964,,,K96243,BimC (bpss1491),chromosome 2,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative glycosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30968000,PubMed,10.3389/fcimb.2019.00063,Front Cell Infect Microbiol. 2019; 9: 63,jo.stevens@roslin.ed.ac.uk,"The bimC mutant was defective in cell to cell spread as demonstrated by ablation of plaque formation in HeLa cells, and by the inability to form multi-nucleated giant cells in J774.1 cells.",V Srinon 2019,2019,2 genes,Srinon-2019-Burkholderia pseudomallei BimC Is,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13685,PHI:9053,UniProt,Q63K73,GenBank,CAH38965,,,K96243,BimA (bpss1492),chromosome 2,,,,,,28450,Burkholderia pseudomallei,,10276,melioidosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30968000,PubMed,10.3389/fcimb.2019.00063,Front Cell Infect Microbiol. 2019; 9: 63,jo.stevens@roslin.ed.ac.uk,"The bimC mutant was defective in cell to cell spread as demonstrated by ablation of plaque formation in HeLa cells, and by the inability to form multi-nucleated giant cells in J774.1 cells.",V Srinon 2019,2019,2 genes,Srinon-2019-Burkholderia pseudomallei BimC Is,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13686,PHI:9054,UniProt,G5EHL4,GenBank,EHA46564,,,70-15,MoMCP1,chromosome 7,,,,,,318829,Magnaporthe oryzae,,YN125,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,cytochrome P450,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30934953,PubMed,10.3390/ijms20071590,Int J Mol Sci. 2019 Mar 29;20(7). pii: E1590,laj7411@126.com,The ΔMomcp1 mutant showed less and smaller mycelium under the Mn2+ treatment compared with WT and the conidial production ability in the ΔMomcp1 mutant was decreased significantly under Mn2+ stress.,Y Wang 2019,2019,1 gene,"Wang-2019-MoMCP1, a Cytochrome P450 Gene, Is R",BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13687,PHI:9055,UniProt,G5EHZ3,GenBank,EHA46518,,,70-15,MoIVD (MGG_02540),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,isovaleryl CoA dehydrogenase,,,,reduced virulence,,no,,yes,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30923517,PubMed,10.3389/fmicb.2019.00444,Front Microbiol. 2019 Mar 14;10:444,gdlufafu@163.com,"The Δmoivd mutant showed reduced growth, decreased conidiation and compromised pathogenicity, while the conidial germination and appressorial formation appeared normal.",Y Li 2019,2019,1 gene,Li-2019-MoIVD-Mediated Leucine Catabolism Is R,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13688,PHI:9055,UniProt,G5EHZ3,GenBank,EHA46518,,,70-15,MoIVD (MGG_02540),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,isovaleryl CoA dehydrogenase,,,,reduced virulence,,no,,yes,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30923517,PubMed,10.3389/fmicb.2019.00444,Front Microbiol. 2019 Mar 14;10:444,gdlufafu@163.com,"The Δmoivd mutant showed reduced growth, decreased conidiation and compromised pathogenicity, while the conidial germination and appressorial formation appeared normal.",Y Li 2019,2019,1 gene,Li-2019-MoIVD-Mediated Leucine Catabolism Is R,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13689,PHI:9056,UniProt,I1RBF3,GenBank,CEF72891,,,PH-1,FgTRR (FGSG_00871),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,inflorescence; leaf,thioredoxin reductase,,,,reduced virulence,,,,,,reduced,aberrant,reduced; aberrant,reduced,no,NaCl; KCl; sorbitol; Congo red (CR); SDS; H2O2; menadione,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30899249,PubMed,10.3389/fmicb.2019.00393,Front Microbiol. 2019 Mar 7;10:393,liangyc@sdau.edu.cn,ΔTRR mutants were more sensitive to oxidative stress and aggravated apoptosis-like cell death compared with the wild type strain.,X Fan 2019,2019,1 gene,Fan-2019-Thioredoxin Reductase Is Involved in,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13690,PHI:9056,UniProt,I1RBF3,GenBank,CEF72891,,,PH-1,FgTRR (FGSG_00871),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,corn silk,thioredoxin reductase,,,,reduced virulence,,,,,,reduced,aberrant,reduced; aberrant,reduced,no,NaCl; KCl; sorbitol; Congo red (CR); SDS; H2O2; menadione,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,30899249,PubMed,10.3389/fmicb.2019.00393,Front Microbiol. 2019 Mar 7;10:393,liangyc@sdau.edu.cn,ΔTRR mutants were more sensitive to oxidative stress and aggravated apoptosis-like cell death compared with the wild type strain.,X Fan 2019,2019,1 gene,Fan-2019-Thioredoxin Reductase Is Involved in,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13691,PHI:9057,UniProt,Q9P8P2,GenBank,AF223383_1,,,H99,plb1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,secreted phospholipase B,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30921435,PubMed,10.1371/journal.ppat.1007597,PLoS Pathog. 2019 Mar 28;15(3):e1007597,s.a.johnston@sheffield.ac.uk,Prostaglandin E2 was required by C. neoformans for proliferation within macrophages and in vivo during infection in eicosanoid deficient cryptococcal mutants Δplb1 and Δlac1.,R J Evans 2019,2019,2 genes,Evans-2019-15-keto-prostaglandin E2 activates,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13692,PHI:9057,UniProt,Q9P8P2,GenBank,AF223383_1,,,H99,plb1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,secreted phospholipase B,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30921435,PubMed,10.1371/journal.ppat.1007597,PLoS Pathog. 2019 Mar 28;15(3):e1007597,s.a.johnston@sheffield.ac.uk,Prostaglandin E2 was required by C. neoformans for proliferation within macrophages and in vivo during infection in eicosanoid deficient cryptococcal mutants Δplb1 and Δlac1.,R J Evans 2019,2019,2 genes,Evans-2019-15-keto-prostaglandin E2 activates,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13693,PHI:9058,UniProt,J9VY90,GenBank,AFR96690,,,H99,lac1,chromosome 8,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,laccase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30921435,PubMed,10.1371/journal.ppat.1007597,PLoS Pathog. 2019 Mar 28;15(3):e1007597,s.a.johnston@sheffield.ac.uk,Prostaglandin E2 was required by C. neoformans for proliferation within macrophages and in vivo during infection in eicosanoid deficient cryptococcal mutants Δplb1 and Δlac1.,R J Evans 2019,2019,2 genes,Evans-2019-15-keto-prostaglandin E2 activates,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13694,PHI:9058,UniProt,J9VY90,GenBank,AFR96690,,,H99,lac1,chromosome 8,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,laccase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30921435,PubMed,10.1371/journal.ppat.1007597,PLoS Pathog. 2019 Mar 28;15(3):e1007597,s.a.johnston@sheffield.ac.uk,Prostaglandin E2 was required by C. neoformans for proliferation within macrophages and in vivo during infection in eicosanoid deficient cryptococcal mutants Δplb1 and Δlac1.,R J Evans 2019,2019,2 genes,Evans-2019-15-keto-prostaglandin E2 activates,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13695,PHI:9059,,no data found,GenBank,VDAG_JR2_Chr1g18420a,,,,VdFKBP12 (VDAG_JR2_Chr1g18420a),chromosome 1,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,rapamycin binding protein,,,,reduced virulence,,,,,,,,wild type,,no,rapamycin,rapamycin: CHEBI:9168,,,,,other evidence: overexpressing transgenic plants,,,YVS,30918504,PubMed,10.3389/fmicb.2019.00501,Front Microbiol. 2019 Mar 13;10:501,renmaozhi@cqu.edu.cn,Deletion of VdFKBP12 (Mfkbp12) led to resistance to RAP in V. dahliae.,L Li 2019,2019,1 gene,Li-2019-Functional Characterization of Target,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13696,PHI:9060,UniProt,Q0P928,GenBank,CAL35343,,,NCTC 11168,HtrA,,protease-inactive HtrA-S197A,,,,,197,Campylobacter jejuni,192222,NCTC 11168,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-10<-/->),,,stomach; ileum; duodenum; colon,secreted serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30984628,PubMed,10.3389/fcimb.2019.00079,Front Cell Infect Microbiol. 2019 Mar 29;9:79,markus.heimesaat@charite.de,"HtrA's protease activity was not required for intestinal colonization and establishment of disease, but aggravated campylobacteriosis by triggering apoptosis and pro-inflammatory immune responses.",A M Schmidt 2019,2019,1 gene,Schmidt-2019-Protease Activity of Campylobacte,BATCH_092A,2019-04-01,MC,,,,,,,,,,,,,
,,Record 13697,PHI:5776,UniProt,I1RJK1,Ensembl Genomes,FgramPH1_01t14279,,,PH-1,Fgsg04023,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 97.9%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13698,PHI:5777,UniProt,I1S3J6,Ensembl Genomes,FgramPH1_01t21925,,,PH-1,Fgsg11381,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 107.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13699,PHI:5778,,no data found,Broad,FGSG_11351,,,PH-1,Fgsg11351,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 109.4%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13700,PHI:5779,UniProt,I1RBX1,Ensembl Genomes,FgramPH1_01t02657,,,PH-1,Fgsg01064,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 85.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13701,PHI:5780,UniProt,A0A0E0S648,Ensembl Genomes,FgramPH1_01t14341,,,PH-1,Fgsg04051,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 106.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13702,PHI:5781,UniProt,I1RG07,Ensembl Genomes,FgramPH1_01t06371,,,PH-1,PRE2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,defective,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 106.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13703,PHI:5782,,no data found,Broad,FGSG_03091,,,PH-1,Fgsg03091,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,increased,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 94.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13704,PHI:5783,UniProt,I1RW42,Ensembl Genomes,FgramPH1_01t10103,,,PH-1,Fgsg08496,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 100%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13705,PHI:5784,UniProt,I1RNJ6,Ensembl Genomes,FgramPH1_01t18251,,,PH-1,Fgsg05579,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 89.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13706,PHI:5785,UniProt,I1RTP1,Ensembl Genomes,FgramPH1_01t25085,,,PH-1,Fgsg07554,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 89.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13707,PHI:5786,UniProt,I1RCV8,Ensembl Genomes,FgramPH1_01t03539,,,PH-1,Fgsg01440,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 108.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13708,PHI:5787,UniProt,A0A1C3YMJ9,Ensembl Genomes,FgramPH1_01t11969,,,PH-1,Fgsg03064,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 102%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13709,PHI:5788,UniProt,A0A1C3YMR1,Ensembl Genomes,FgramPH1_01t12337,,,PH-1,Fgsg03215,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 92%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13710,PHI:5789,,no data found,Broad,FGSG_09749,,,PH-1,Fgsg09749,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,increased,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 95.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13711,PHI:5790,UniProt,I1RJE6,Ensembl Genomes,FgramPH1_01t14135,,,PH-1,Fgsg03962,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 98.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13712,PHI:5791,,no data found,Broad,FGSG_02402,,,PH-1,Fgsg02402,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 116.9%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13713,PHI:5792,UniProt,I1RI51,Ensembl Genomes,FgramPH1_01t12975,,,PH-1,Fgsg03476,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 99%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13714,PHI:5793,UniProt,I1RF68,Ensembl Genomes,FgramPH1_01t05613,,,PH-1,Fgsg02334,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 102%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13715,PHI:5794,UniProt,A0A1C3YMM6,Ensembl Genomes,FgramPH1_01t12299,,,PH-1,Fgsg12490,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 103.4%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13716,PHI:5795,UniProt,I1RHP9,Ensembl Genomes,FgramPH1_01t12571,,,PH-1,Fgsg03310,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 91.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13717,PHI:5796,UniProt,A0A1C3YJ97,Ensembl Genomes,FgramPH1_01t06157,,,PH-1,Fgsg02569,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 96.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13718,PHI:5797,UniProt,I1R9P8,Ensembl Genomes,FgramPH1_01t00541,,,PH-1,Fgsg00201,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 97.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13719,PHI:5798,,no data found,Broad,FGSG_04815,,,PH-1,Fgsg04815,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 106.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13720,PHI:5799,,no data found,Broad,FGSG_10958,,,PH-1,Fgsg10958,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 106.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13721,PHI:5800,UniProt,I1S3J8,Ensembl Genomes,FgramPH1_01t21935,,,PH-1,Fgsg11385,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 104.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13722,PHI:5801,UniProt,A0A098DMJ4,Ensembl Genomes,FgramPH1_01t15745,,,PH-1,Fgsg04628,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 93.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13723,PHI:5802,UniProt,A0A098DTB5,Ensembl Genomes,FgramPH1_01t24387,,,PH-1,PRE1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 112.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13724,PHI:5803,,no data found,Broad,FGSG_00527,,,PH-1,Fgsg00527,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 97.9%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13725,PHI:5804,UniProt,A0A1C3YJF1,Ensembl Genomes,FgramPH1_01t16867,,,PH-1,Fgsg05006,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 95%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13726,PHI:5805,,no data found,Broad,FGSG_09693,,,PH-1,Fgsg09693,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 94.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13727,PHI:5806,UniProt,I1RMP5,Ensembl Genomes,FgramPH1_01t17439,,,PH-1,Fgsg05239,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,increased,defective,wild type,,no,,,,,,,gene deletion; complementation,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 92.7%; forms only proto-perithecia on carrot agar,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13728,PHI:5807,UniProt,I1RGZ0,Ensembl Genomes,FgramPH1_01t11875,,,PH-1,Fgsg03023,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 96.9%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13729,PHI:5808,UniProt,I1RU37,Ensembl Genomes,FgramPH1_01t25463,,,PH-1,Fgsg07716,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 83.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13730,PHI:5809,UniProt,I1RDZ2,Ensembl Genomes,FgramPH1_01t04509,,,PH-1,Fgsg01861,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 112.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13731,PHI:5810,UniProt,I1RBN5,Ensembl Genomes,FgramPH1_01t02427,,,PH-1,Fgsg00966,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 101.4%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13732,PHI:5811,UniProt,I1RUA7,Ensembl Genomes,FgramPH1_01t25677,,,PH-1,Fgsg07792,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 102.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13733,PHI:5812,UniProt,I1RKT3,Ensembl Genomes,FgramPH1_01t15453,,,PH-1,Fgsg04500,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 113.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13734,PHI:5813,,no data found,Broad,FGSG_04865,,,PH-1,Fgsg04865,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 105.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13735,PHI:5814,,no data found,Broad,FGSG_03192,,,PH-1,Fgsg03192,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 93.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13736,PHI:5815,UniProt,I1RIF6,Ensembl Genomes,FgramPH1_01t13229,,,PH-1,Fgsg03588,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 101.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13737,PHI:5816,UniProt,I1RDW5,Ensembl Genomes,FgramPH1_01t04433,,,PH-1,Fgsg01833,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 116.4%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13738,PHI:5817,UniProt,I1S3G2,Ensembl Genomes,FgramPH1_01t21831,,,PH-1,Fgsg11343,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 103.4%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13739,PHI:5818,UniProt,A0A1C3YKY7,Ensembl Genomes,FgramPH1_01t24051,,,PH-1,Fgsg07136,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 100.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13740,PHI:5819,UniProt,I1RYC5,Ensembl Genomes,FgramPH1_01t27249,,,PH-1,Fgsg09370,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 94.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13741,PHI:5820,UniProt,I1RU73,Ensembl Genomes,FgramPH1_01t25579,,,PH-1,Fgsg07757,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,increased,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 95.6%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13742,PHI:5821,UniProt,I1RLF3,Ensembl Genomes,FgramPH1_01t16225,,,PH-1,Fgsg04749,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 91.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13743,PHI:5822,UniProt,I1REA6,Ensembl Genomes,FgramPH1_01t04803,,,PH-1,Fgsg01989,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 87.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13744,PHI:5823,,no data found,Broad,FGSG_11529,,,PH-1,Fgsg11529,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 98.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13745,PHI:5824,UniProt,I1RGH9,Ensembl Genomes,FgramPH1_01t11443,,,PH-1,Fgsg02844,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 104.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13746,PHI:5825,,no data found,Broad,FGSG_02614,,,PH-1,GIV2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,reduced virulence,,,,,,increased,wild type,wild type,,no,,,,,,,gene deletion; complementation,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 27.5%; defective in cell-to-cell spreading,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13747,PHI:5826,UniProt,I1RYB0,Ensembl Genomes,FgramPH1_01t27289,,,PH-1,GIV4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,reduced virulence,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 74.4%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13748,PHI:5827,,no data found,Broad,FGSG_02981,,,PH-1,GIV5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 74.6%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13749,PHI:5828,UniProt,I1RP41,Ensembl Genomes,FgramPH1_01t18775,,,PH-1,GIV6,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 100.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13750,PHI:5829,,no data found,Broad,FGSG_03104,,,PH-1,GIV3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,reduced virulence,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion; complementation,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 58.6%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13751,PHI:5830,UniProt,I1RIP6,Ensembl Genomes,FgramPH1_01t13467,,,PH-1,Fgsg03688,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 117.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13752,PHI:5831,,no data found,Broad,FGSG_13461,,,PH-1,Fgsg13461,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,increased,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 112.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13753,PHI:5832,,no data found,Broad,FGSG_02134,,,PH-1,Fgsg02134,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 100.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13754,PHI:5833,UniProt,A0A1C3YI15,Ensembl Genomes,FgramPH1_01t02493,,,PH-1,Fgsg00994,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 92.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13755,PHI:5834,UniProt,I1RGX7,Ensembl Genomes,FgramPH1_01t11837,,,PH-1,Fgsg03009,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 112.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13756,PHI:5835,UniProt,I1RR34,Ensembl Genomes,FgramPH1_01t22539,,,PH-1,Fgsg06541,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,increased,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 99%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13757,PHI:5836,UniProt,I1RHZ0,Ensembl Genomes,FgramPH1_01t12817,,,PH-1,Fgsg03409,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 85.9%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13758,PHI:5837,,no data found,Broad,FGSG_03464,,,PH-1,Fgsg03464,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 101.6%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13759,PHI:5838,UniProt,A0A098DCR9,Ensembl Genomes,FgramPH1_01t09881,,,PH-1,Fgsg08408,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,increased,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 97.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13760,PHI:5839,UniProt,A0A1C3YL50,Ensembl Genomes,FgramPH1_01t24935,,,PH-1,Fgsg07489,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,increased,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 93.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13761,PHI:5840,UniProt,I1RLD6,Ensembl Genomes,FgramPH1_01t16185,,,PH-1,Fgsg04731,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 100.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13762,PHI:5841,UniProt,I1RLA6,Ensembl Genomes,FgramPH1_01t16083,,,PH-1,GIV1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,reduced virulence,,,,,,increased,wild type,wild type,,no,,,,,,,gene deletion; complementation,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 37.5%; defective in infection-cushion formation; Expressing a dominant active FST7 partially rescues the defects of giv1 mutant.,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13763,PHI:5842,UniProt,I1S9F6,Ensembl Genomes,FgramPH1_01t28239,,,PH-1,Fgsg13487,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 89.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13764,PHI:5843,UniProt,I1RUF1,Ensembl Genomes,FgramPH1_01t25793,,,PH-1,Fgsg07841,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 96.9%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13765,PHI:5844,UniProt,A0A1C3YMZ9,Ensembl Genomes,FgramPH1_01t14063,,,PH-1,Fgsg03932,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 109.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13766,PHI:5845,UniProt,I1RTZ3,Ensembl Genomes,FgramPH1_01t25327,,,PH-1,Fgsg07663,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 99.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13767,PHI:5846,UniProt,A0A098DRE2,Ensembl Genomes,FgramPH1_01t25309,,,PH-1,Fgsg07655,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 107.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13768,PHI:5847,UniProt,A0A098DG53,Ensembl Genomes,FgramPH1_01t12209,,,PH-1,Fgsg16316,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 95.1%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13769,PHI:5848,,no data found,Broad,FGSG_03005,,,PH-1,Fgsg03005,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 92.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13770,PHI:5849,UniProt,I1RI77,Ensembl Genomes,FgramPH1_01t13041,,,PH-1,Fgsg03504,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 114.1%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13771,PHI:5850,UniProt,I1S068,Ensembl Genomes,FgramPH1_01t07245,,,PH-1,Fgsg10085,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 110.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13772,PHI:5851,UniProt,I1RM58,Ensembl Genomes,FgramPH1_01t16943,,,PH-1,Fgsg05039,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 91.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13773,PHI:5852,UniProt,I1RHS3,Ensembl Genomes,FgramPH1_01t12633,,,PH-1,Fgsg03336,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 97.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13774,PHI:5853,,no data found,Broad,FGSG_04825,,,PH-1,GCD1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 96.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13775,PHI:5854,UniProt,A0A1C3YKG6,Ensembl Genomes,FgramPH1_01t21947,,,PH-1,GCD2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 97.6%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13776,PHI:5855,UniProt,A0A1C3YJ88,Ensembl Genomes,FgramPH1_01t08575,,,PH-1,GCD3,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 93.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13777,PHI:5856,,no data found,Broad,FGSG_12419,,,PH-1,GCD4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 102.1%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13778,PHI:5857,UniProt,A0A1C3YIJ6,Ensembl Genomes,FgramPH1_01t05763,,,PH-1,GCD5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 93.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13779,PHI:5858,,no data found,Broad,FGSG_03707,,,PH-1,GCD6,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 95.1%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13780,PHI:5859,UniProt,A0A1C3YMZ2,Ensembl Genomes,FgramPH1_01t13985,,,PH-1,GCD7,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 115.9%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13781,PHI:5860,UniProt,I1RER0,Ensembl Genomes,FgramPH1_01t05193,,,PH-1,GCD8,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 93.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13782,PHI:5861,,no data found,Broad,FGSG_02374,,,PH-1,GCD9,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 102.1%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13783,PHI:5862,UniProt,I1RUE9,Ensembl Genomes,FgramPH1_01t25789,,,PH-1,GCD10,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 98.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13784,PHI:5863,UniProt,I1RP68,Ensembl Genomes,FgramPH1_01t18835,,,PH-1,GCD11,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 102.1%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13785,PHI:5864,UniProt,A0A098DM90,Ensembl Genomes,FgramPH1_01t15521,,,PH-1,GCD12,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 107.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13786,PHI:5865,UniProt,I1RDT9,Ensembl Genomes,FgramPH1_01t04377,,,PH-1,Fgsg01806,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 102.1%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13787,PHI:5866,UniProt,A0A1C3YMR4,Ensembl Genomes,FgramPH1_01t12389,,,PH-1,Fgsg03237,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 96.9%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13788,PHI:5867,,no data found,Broad,FGSG_03959,,,PH-1,Fgsg03959,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 109.2%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13789,PHI:5868,UniProt,A0A1C3YMS1,Ensembl Genomes,FgramPH1_01t12565,,,PH-1,Fgsg12463,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 87.5%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13790,PHI:5869,UniProt,A0A1C3YK62,Ensembl Genomes,FgramPH1_01t20281,,,PH-1,Fgsg11598,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 111.1%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13791,PHI:5870,UniProt,I1RJX5,Ensembl Genomes,FgramPH1_01t14631,,,PH-1,Fgsg04159,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 90.6%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13792,PHI:5871,UniProt,A0A1C3YKC6,Ensembl Genomes,FgramPH1_01t21179,,,PH-1,Fgsg11080,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 101.6%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13793,PHI:5872,UniProt,A0A1C3YMM2,Ensembl Genomes,FgramPH1_01t11465,,,PH-1,Fgsg02853,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 102.4%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13794,PHI:5873,UniProt,I1RQT9,Ensembl Genomes,FgramPH1_01t22281,,,PH-1,Fgsg06439,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 100.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13795,PHI:5874,UniProt,I1RF11,Ensembl Genomes,FgramPH1_01t05487,,,PH-1,Fgsg02274,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 100.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13796,PHI:5875,,no data found,Broad,FGSG_03823,,,PH-1,Fgsg03823,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 91.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13797,PHI:5876,UniProt,I1RHL8,Ensembl Genomes,FgramPH1_01t12485,,,PH-1,Fgsg03277,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 93.1%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13798,PHI:5877,,no data found,Broad,FGSG_07601,,,PH-1,Fgsg07601,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 91.7%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13799,PHI:5878,,no data found,Broad,FGSG_05722,,,PH-1,Fgsg05722,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 111.4%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13800,PHI:5879,,no data found,Broad,FGSG_12205,,,PH-1,Fgsg12205,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 95.8%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13801,PHI:5880,,no data found,Broad,FGSG_12474,,,PH-1,Fgsg12474,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4564,Triticum (related: wheat),cv. Xiaoyan 22,,,spike,GPCR gene,,,,unaffected pathogenicity,,,,,,reduced,wild type,wild type,,no,,,,,,,gene deletion,,MU,MU,31160822,PubMed,10.1038/s41564-019-0468-8,,jinrong@purdue.edu,Virulence value = 88.3%,C Jiang 2019,2019,,,,2019-07-31,RRes,"Xu, X. R.",,,,,,,,,,,,
,,Record 13802,PHI:9061,UniProt,Q2YJ35,GenBank,CAJ12598,,,2308,nikR (bab2_0432),chromosome II,,,,,,235,Brucella abortus,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage; spleen,nickel-responsive regulator,,,,unaffected pathogenicity,,,,,,,,,,no,NiSO4; CuCl2; ZnCl2,NiSO4: CHEBI:53001; CuCl2: CHEBI:49553; ZnCl2: CHEBI:49976,,,,,gene mutation,,,YVS,30062985,PubMed,10.1099/mic.0.000702,Microbiology. 2018 Oct;164(10):1320-1325,caswellc@vt.edu,"Deletion of nikR in B. abortus did not alter the ability of B. abortus to survive and replicate in peritoneally derived macrophages, or to colonize the spleens of BALB/c mice infected intraperitoneally.",J A Budnick 2018,2018,1 gene,Budnick-2018-Defining the regulatory mechanism,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13803,PHI:9062,UniProt,A0A098DJU9,GenBank,ESU09330,,,PH-1; NRRL 31084,katG2 (FGSG_12369),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68; cv. Bobwhite,,,spike; coleoptile,putative secreted catalase-peroxidase,,,,reduced virulence,,,,,,,wild type,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30919582,PubMed,10.1111/mpp.12785,Mol Plant Pathol. 2019 May;20(5):685-700,whtang@sibs.ac.cn,KatG2 contributed to F. graminearum pathogenicity by alleviating oxidative stress in the vicinity of invasion hyphae.,Y Guo 2019,2019,1 gene,Guo-2019-The spatiotemporal control of KatG2 c,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13804,PHI:9062,UniProt,A0A098DJU9,GenBank,ESU09330,,,PH-1; NRRL 31084,katG2 (FGSG_12369),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,stem,putative secreted catalase-peroxidase,,,,reduced virulence,,,,,,,wild type,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30919582,PubMed,10.1111/mpp.12785,Mol Plant Pathol. 2019 May;20(5):685-700,whtang@sibs.ac.cn,KatG2 contributed to F. graminearum pathogenicity by alleviating oxidative stress in the vicinity of invasion hyphae.,Y Guo 2019,2019,1 gene,Guo-2019-The spatiotemporal control of KatG2 c,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13805,PHI:9063,UniProt,Q4WSD1,GenBank,afu1g13190,,,,Afmac1,,,,,,,746128,Aspergillus fumigatus,,A1160,invasive aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,putative Cu detoxification transcription factor,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28803907,PubMed,10.1016/j.fgb.2017.08.003,Fungal Genet Biol. 2017 Oct;107:31-43,linglu@njnu.edu.cn,"Cu starvation-induced Mac1 was responsible for normal growth, conidiation and the intracellular Cu content in A. fumigatus",Z Cai 2017,2017,1 gene,Cai-2017-Cu-sensing transcription factor Mac1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13806,PHI:9064,UniProt,B8N6C9,GenBank,EED54641,,,NRRL3357,cap (AFLA_018930),,,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::pyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,adenylate cyclase-associated protein,,,mycotoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30916945,PubMed,10.1021/acs.jafc.8b07115,J Agric Food Chem. 2019 Apr 17;67(15):4200-4213,wshyyl@sina.com,The Δcap mutant exhibited increasing aflatoxin B1 (AFB1) production compared to the wild type.,K Yang 2019,2019,1 gene,Yang-2019-Cyclase-Associated Protein Cap with,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13807,PHI:9064,UniProt,B8N6C9,GenBank,EED54641,,,NRRL3357,cap (AFLA_018930),,Cap-S35A point mutation,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::pyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,adenylate cyclase-associated protein,,,mycotoxin biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30916945,PubMed,10.1021/acs.jafc.8b07115,J Agric Food Chem. 2019 Apr 17;67(15):4200-4213,wshyyl@sina.com,Phosphorylation of Cap at S35 was dispensable for fungal growth and mycotoxin biosynthesis.,K Yang 2019,2019,1 gene,Yang-2019-Cyclase-Associated Protein Cap with,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13808,PHI:9064,UniProt,B8N6C9,GenBank,EED54641,,,NRRL3357,cap (AFLA_018930),,capΔACB,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::pyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,adenylate cyclase-associated protein,,,mycotoxin biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30916945,PubMed,10.1021/acs.jafc.8b07115,J Agric Food Chem. 2019 Apr 17;67(15):4200-4213,wshyyl@sina.com,P1 and CARP domains were critical for the fungal development and virulence of Cap in A. flavus.,K Yang 2019,2019,1 gene,Yang-2019-Cyclase-Associated Protein Cap with,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13809,PHI:9064,UniProt,B8N6C9,GenBank,EED54641,,,NRRL3357,cap (AFLA_018930),,capΔP1,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::pyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,adenylate cyclase-associated protein,,,mycotoxin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30916945,PubMed,10.1021/acs.jafc.8b07115,J Agric Food Chem. 2019 Apr 17;67(15):4200-4213,wshyyl@sina.com,P1 and CARP domains were critical for the fungal development and virulence of Cap in A. flavus.,K Yang 2019,2019,1 gene,Yang-2019-Cyclase-Associated Protein Cap with,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13810,PHI:9064,UniProt,B8N6C9,GenBank,EED54641,,,NRRL3357,cap (AFLA_018930),,capΔP2,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::pyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,adenylate cyclase-associated protein,,,mycotoxin biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30916945,PubMed,10.1021/acs.jafc.8b07115,J Agric Food Chem. 2019 Apr 17;67(15):4200-4213,wshyyl@sina.com,P1 and CARP domains were critical for the fungal development and virulence of Cap in A. flavus.,K Yang 2019,2019,1 gene,Yang-2019-Cyclase-Associated Protein Cap with,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13811,PHI:9064,UniProt,B8N6C9,GenBank,EED54641,,,NRRL3357,cap (AFLA_018930),,capΔCARP,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::pyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,adenylate cyclase-associated protein,,,mycotoxin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30916945,PubMed,10.1021/acs.jafc.8b07115,J Agric Food Chem. 2019 Apr 17;67(15):4200-4213,wshyyl@sina.com,P1 and CARP domains were critical for the fungal development and virulence of Cap in A. flavus.,K Yang 2019,2019,1 gene,Yang-2019-Cyclase-Associated Protein Cap with,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13812,PHI:9065,,no data found,,,,,,cbu0414 (coxH1),,cbu0414::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13813,PHI:9066,UniProt,Q83E23,GenBank,AAO90059,,,RSA 493,cbu0513,,cbu0513::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13814,PHI:9067,UniProt,Q83CX3,GenBank,AAO90500,,,RSA 493,cbu0978 (cem3),,cbu0978::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13815,PHI:9068,UniProt,Q83BV2,GenBank,AAO90890,,,RSA 493,cbu1387 (cem6),,cbu1387::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13816,PHI:9069,UniProt,A0A142K489,GenBank,AMS00631,,,F3,cbu1524 (caeA),,cbu1524::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13817,PHI:9070,UniProt,Q83AX5,GenBank,AAO91246,,,RSA 493,cbu1752,,cbu1752::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13818,PHI:9071,UniProt,Q83A80,GenBank,AAO91515,,,RSA 493,cbu2028,,cbu2028::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13819,PHI:9065,,no data found,,,,,,cbu0414 (coxH1),,cbu0414::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13820,PHI:9066,UniProt,Q83E23,GenBank,AAO90059,,,RSA 493,cbu0513,,cbu0513::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13821,PHI:9067,UniProt,Q83CX3,GenBank,AAO90500,,,RSA 493,cbu0978 (cem3),,cbu0978::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13822,PHI:9068,UniProt,Q83BV2,GenBank,AAO90890,,,RSA 493,cbu1387 (cem6),,cbu1387::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13823,PHI:9069,UniProt,A0A142K489,GenBank,AMS00631,,,F3,cbu1524 (caeA),,cbu1524::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13824,PHI:9070,UniProt,Q83AX5,GenBank,AAO91246,,,RSA 493,cbu1752,,cbu1752::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13825,PHI:9071,UniProt,Q83A80,GenBank,AAO91515,,,RSA 493,cbu2028,,cbu2028::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13826,PHI:9065,,no data found,,,,,,cbu0414 (coxH1),,cbu0414::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13827,PHI:9066,UniProt,Q83E23,GenBank,AAO90059,,,RSA 493,cbu0513,,cbu0513::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13828,PHI:9067,UniProt,Q83CX3,GenBank,AAO90500,,,RSA 493,cbu0978 (cem3),,cbu0978::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13829,PHI:9068,UniProt,Q83BV2,GenBank,AAO90890,,,RSA 493,cbu1387 (cem6),,cbu1387::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13830,PHI:9069,UniProt,A0A142K489,GenBank,AMS00631,,,F3,cbu1524 (caeA),,cbu1524::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13831,PHI:9070,UniProt,Q83AX5,GenBank,AAO91246,,,RSA 493,cbu1752,,cbu1752::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13832,PHI:9071,UniProt,Q83A80,GenBank,AAO91515,,,RSA 493,cbu2028,,cbu2028::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13833,PHI:9065,,no data found,,,,,,cbu0414 (coxH1),,cbu0414::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO cell line,,,ovary cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13834,PHI:9066,UniProt,Q83E23,GenBank,AAO90059,,,RSA 493,cbu0513,,cbu0513::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO cell line,,,ovary cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13835,PHI:9067,UniProt,Q83CX3,GenBank,AAO90500,,,RSA 493,cbu0978 (cem3),,cbu0978::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO cell line,,,ovary cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13836,PHI:9068,UniProt,Q83BV2,GenBank,AAO90890,,,RSA 493,cbu1387 (cem6),,cbu1387::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO cell line,,,ovary cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13837,PHI:9069,UniProt,A0A142K489,GenBank,AMS00631,,,F3,cbu1524 (caeA),,cbu1524::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO cell line,,,ovary cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13838,PHI:9070,UniProt,Q83AX5,GenBank,AAO91246,,,RSA 493,cbu1752,,cbu1752::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO cell line,,,ovary cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13839,PHI:9071,UniProt,Q83A80,GenBank,AAO91515,,,RSA 493,cbu2028,,cbu2028::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10036,Mesocricetus auratus (related: golden hamster),CHO cell line,,,ovary cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13840,PHI:9065,,no data found,,,,,,cbu0414 (coxH1),,cbu0414::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13841,PHI:9066,UniProt,Q83E23,GenBank,AAO90059,,,RSA 493,cbu0513,,cbu0513::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13842,PHI:9067,UniProt,Q83CX3,GenBank,AAO90500,,,RSA 493,cbu0978 (cem3),,cbu0978::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13843,PHI:9068,UniProt,Q83BV2,GenBank,AAO90890,,,RSA 493,cbu1387 (cem6),,cbu1387::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13844,PHI:9069,UniProt,A0A142K489,GenBank,AMS00631,,,F3,cbu1524 (caeA),,cbu1524::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13845,PHI:9070,UniProt,Q83AX5,GenBank,AAO91246,,,RSA 493,cbu1752,,cbu1752::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13846,PHI:9071,UniProt,Q83A80,GenBank,AAO91515,,,RSA 493,cbu2028,,cbu2028::Tn,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,effector protein,,,Coxiella-containing vacuole (CCV) biogenesis,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29339460,PubMed,10.1128/IAI.00758-17,Infect Immun. 2018 Mar 22;86(4). pii: e00758-17,craig.roy@yale.edu,"The cbu2028::Tn mutant, though unable to develop large CCVs, had intracellular replication rates similar to the rate of the parental strain of C. burnetii, whereas the other six effector mutants defective in CCV biogenesis displayed significant reductions in intracellular replication.",E Crabill 2018,2018,7 genes,Crabill-2018-Dot_Icm-translocated proteins imp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13847,PHI:9072,UniProt,E3QPY3,GenBank,EFQ32921.1,,,,nps6,,,,,,,31870,Colletotrichum graminicola,,CgM2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),UH002 line,,,leaf,siderophore biosynthesis protein,,,siderophore biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,24512386,PubMed,10.1111/ppl.12166,Physiol Plant. 2014 Jul;151(3):280-92,vonwiren@ipk-gatersleben.de,The necrotrophic growth phase of C. graminicola was largely independent of the Fe nutritional status of maize leaves.,F Ye 2014,2014,4 genes,Ye-2014-An adequate Fe nutritional status of m,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13848,PHI:9073,UniProt,E3QKK8,GenBank,EFQ31396.1,,,,sid1,,,,,,,31870,Colletotrichum graminicola,,CgM2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),UH002 line,,,leaf,siderophore biosynthesis protein,,,siderophore biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,24512386,PubMed,10.1111/ppl.12166,Physiol Plant. 2014 Jul;151(3):280-92,vonwiren@ipk-gatersleben.de,The necrotrophic growth phase of C. graminicola was largely independent of the Fe nutritional status of maize leaves.,F Ye 2014,2014,4 genes,Ye-2014-An adequate Fe nutritional status of m,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13849,PHI:9074,UniProt,E3QRA4,GenBank,EFQ33392.1,,,,fet3-1,,,,,,,31870,Colletotrichum graminicola,,CgM2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),UH002 line,,,leaf,ferroxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,24512386,PubMed,10.1111/ppl.12166,Physiol Plant. 2014 Jul;151(3):280-92,vonwiren@ipk-gatersleben.de,The necrotrophic growth phase of C. graminicola was largely independent of the Fe nutritional status of maize leaves.,F Ye 2014,2014,4 genes,Ye-2014-An adequate Fe nutritional status of m,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13850,PHI:9074,UniProt,E3QRA4,GenBank,EFQ33392.1,,,,fet3-1,,,,,,PHI:9075,31870,Colletotrichum graminicola,,CgM2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),UH002 line,,,leaf,ferroxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,24512386,PubMed,10.1111/ppl.12166,Physiol Plant. 2014 Jul;151(3):280-92,vonwiren@ipk-gatersleben.de,The necrotrophic growth phase of C. graminicola was largely independent of the Fe nutritional status of maize leaves.,F Ye 2014,2014,4 genes,Ye-2014-An adequate Fe nutritional status of m,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13851,PHI:9075,UniProt,E3Q7G1,GenBank,EFQ26799.1,,,,fet3-2,,,,,,PHI:9074,31870,Colletotrichum graminicola,,CgM2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),UH002 line,,,leaf,ferroxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,24512386,PubMed,10.1111/ppl.12166,Physiol Plant. 2014 Jul;151(3):280-92,vonwiren@ipk-gatersleben.de,The necrotrophic growth phase of C. graminicola was largely independent of the Fe nutritional status of maize leaves.,F Ye 2014,2014,4 genes,Ye-2014-An adequate Fe nutritional status of m,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13852,PHI:9076,UniProt,A6UZF3,GenBank,PTC38980,,,CLJ1,Vfr (PSPA7_0793),,,,,,,287,Pseudomonas aeruginosa,,IHMA879472,infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29632090,PubMed,10.1128/JB.00135-18,J Bacteriol. 2018 May 24;200(12). pii: e00135-18,sylvie.elsen@cea.fr,"The Vfr binding sequence in the exlBA promoter was mutated in situ, resulting in reduced cytotoxicity of the mutant, showing that Vfr was required for the exlBA expression during intoxication of epithelial cells.",A Berry 2018,2018,3 genes,Berry-2018-cAMP and Vfr control Exolysin expre,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13853,PHI:9077,UniProt,A0A0V3MA40,GenBank,PTC35039,,,CLJ1,exlA,,,,,,,287,Pseudomonas aeruginosa,,IHMA879472,infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,exolysin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29632090,PubMed,10.1128/JB.00135-18,J Bacteriol. 2018 May 24;200(12). pii: e00135-18,sylvie.elsen@cea.fr,"The Vfr binding sequence in the exlBA promoter was mutated in situ, resulting in reduced cytotoxicity of the mutant, showing that Vfr was required for the exlBA expression during intoxication of epithelial cells.",A Berry 2018,2018,3 genes,Berry-2018-cAMP and Vfr control Exolysin expre,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13854,PHI:9078,UniProt,P04739,GenBank,AE004866_7,,,PAO1,pilA,,,,,,,287,Pseudomonas aeruginosa,,IHMA879472,infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,fimbrial protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29632090,PubMed,10.1128/JB.00135-18,J Bacteriol. 2018 May 24;200(12). pii: e00135-18,sylvie.elsen@cea.fr,Vfr also regulated function of type 4 pili shown to facilitate ExlA activity on epithelial cells.,A Berry 2018,2018,3 genes,Berry-2018-cAMP and Vfr control Exolysin expre,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13855,PHI:9079,UniProt,L0AQG4,GenBank,AFZ76985,,,CFCC 1336,pcs,,,,,,,317,Pseudomonas syringae,,pv. syringae strain CFCC 1336,bacterial canker,eudicots,326968,Ziziphus jujuba (related: common jujube),,,,fruit,phosphatidylcholine synthase,,,phosphatidylcholine synthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29146248,PubMed,10.1016/j.micres.2017.10.001,Microbiol Res. 2018 Jan;206:113-120,xgwang@hubu.edu.cn,1336 pcs- mutant was unable to cause necrosis of Chinese date fruits and inhibit fungal growth.,F Cao 2018,2018,1 gene,Cao-2018-Phosphatidylcholine absence affects t,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13856,PHI:9080,UniProt,C9W7X1,GenBank,ACN32207,,,,Cgpks1,,,,,,,31870,Colletotrichum graminicola,,CgM2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Golden Jubilee,,,leaf,polyketide synthase,,,melanin biosynthesis,reduced virulence,,no,yes,,,,,aberrant,wild type,no,,,,,,,gene disruption; gene complementation,,,YVS,24261846,PubMed,10.1094/MPMI-09-13-0267-R,Mol Plant Microbe Interact. 2014 Apr;27(4):315-27,ralf.horbach@landw.uni-halle.de,Nonmelanized Cgpks1 appressoria were sensitive to externally applied cell-wall-degrading enzymes whereas melanized appressoria were not affected.,N Ludwig 2014,2014,1 gene,Ludwig-2014-Melanin is not required for turgor,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13857,PHI:9081,UniProt,Q4WJ81,GenBank,EAL88401,,,Af293,CrzA,chromosome 1,CrzA with 20 phosphorylation sites mutated generated with glutamate substitutions in place of serine/threonine residues at multiple cluster combinations,,,,,746128,Aspergillus fumigatus,,akuBKU80,,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,C2H2 finger domain transcription factor,,,,reduced virulence,,,,,,reduced,,wild type,,no,CaCl2; caspofungin; voriconazole; itraconazole,CaCl2: CHEBI:3312; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076,,,,,gene mutation; gene complementation,,,YVS,30927289,PubMed,10.1111/mmi.14254,Mol Microbiol. 2019 Mar 29,bill.steinbach@duke.edu,Virulence of the CrzA-13 strain was much closer to that of the ΔcrzA strain than to the CrzA-C strain,E K Shwab 2019,2019,1 gene,Shwab-2019-Calcineurin-dependent dephosphoryla,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13858,PHI:9081,UniProt,Q4WJ81,GenBank,EAL88401,,,Af293,CrzA,chromosome 1,CrzA with 20 phosphorylation sites mutated generated with glutamate substitutions in place of serine/threonine residues at multiple cluster combinations,,,,,746128,Aspergillus fumigatus,,akuBKU80,,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,C2H2 finger domain transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,,no,CaCl2; caspofungin; voriconazole; itraconazole,CaCl2: CHEBI:3312; caspofungin: CHEBI:474180; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076,,,,,gene deletion: full; gene complementation,,,YVS,30927289,PubMed,10.1111/mmi.14254,Mol Microbiol. 2019 Mar 29,bill.steinbach@duke.edu,Virulence of the CrzA-13 strain was much closer to that of the ΔcrzA strain than to the CrzA-C strain,E K Shwab 2019,2019,1 gene,Shwab-2019-Calcineurin-dependent dephosphoryla,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13859,PHI:9082,UniProt,Q4X022,GenBank,EAL93793,,,Af293,tptA (AFUA_2G14980),chromosome 2,,,,,,746128,Aspergillus fumigatus,,A1160 (Δku80 pyrG1),invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,thiamine pyrophosphate transporter,,,,reduced virulence,,,,,,reduced,,reduced,,no,FeCl3; bathophenanthroline disulfonate (BPS),FeCl3: CHEBI:30808; bathophenanthroline disulfonate (BPS): CHEBI:78158,,,,,gene deletion: full; gene complementation,,,YVS,30880633,PubMed,10.1080/21505594.2019.1596505,Virulence. 2019 Dec;10(1):234-247,szzhang@njnu.edu.cn,"Overexpression of hapX which is a major transcription factor indispensable for adaptation to iron starvation, greatly rescued the growth defect and siderophore production by A. fumigatus in iron-depleted conditions in the ΔtptA strain.",J Huang 2019,2019,1 gene,Huang-2019-The mitochondrial thiamine pyrophos,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13860,PHI:9083,UniProt,P06203,GenBank,AAL22939,,,LT2,metJ,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,ileum; spleen,master repressor of the methionine regulon,,,methionine metabolism pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29866910,PubMed,10.1128/IAI.00429-18,Infect Immun. 2018 Aug 22;86(9). pii: e00429-18,dennis.ko@duke.edu,"The ΔmetJ mutant displayed reduced motility, host cell pyroptosis and invasion.",J S Bourgeois 2018,2018,2 genes,Bourgeois-2018-Methylthioadenosine suppresses,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13861,PHI:9084,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,ileum; spleen,master SPI-1 regulator,,,methionine metabolism pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29866910,PubMed,10.1128/IAI.00429-18,Infect Immun. 2018 Aug 22;86(9). pii: e00429-18,dennis.ko@duke.edu,"The ΔmetJ mutant displayed reduced motility, host cell pyroptosis and invasion.",J S Bourgeois 2018,2018,2 genes,Bourgeois-2018-Methylthioadenosine suppresses,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13862,PHI:9083,UniProt,P06203,GenBank,AAL22939,,,LT2,metJ,,,,,,PHI:9084,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,ileum; spleen,master repressor of the methionine regulon,,,methionine metabolism pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29866910,PubMed,10.1128/IAI.00429-18,Infect Immun. 2018 Aug 22;86(9). pii: e00429-18,dennis.ko@duke.edu,"The ΔmetJ mutant displayed reduced motility, host cell pyroptosis and invasion.",J S Bourgeois 2018,2018,2 genes,Bourgeois-2018-Methylthioadenosine suppresses,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13863,PHI:9084,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,,,,,PHI:9083,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,ileum; spleen,master SPI-1 regulator,,,methionine metabolism pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29866910,PubMed,10.1128/IAI.00429-18,Infect Immun. 2018 Aug 22;86(9). pii: e00429-18,dennis.ko@duke.edu,"The ΔmetJ mutant displayed reduced motility, host cell pyroptosis and invasion.",J S Bourgeois 2018,2018,2 genes,Bourgeois-2018-Methylthioadenosine suppresses,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13864,PHI:9083,UniProt,P06203,GenBank,AAL22939,,,LT2,metJ,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,primates,9606,Homo sapiens (related: human),LCL 18592,,,lymphoblastoid cell line,master repressor of the methionine regulon,,,methionine metabolism pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29866910,PubMed,10.1128/IAI.00429-18,Infect Immun. 2018 Aug 22;86(9). pii: e00429-18,dennis.ko@duke.edu,"The ΔmetJ mutant displayed reduced motility, host cell pyroptosis and invasion.",J S Bourgeois 2018,2018,2 genes,Bourgeois-2018-Methylthioadenosine suppresses,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13865,PHI:9083,UniProt,P06203,GenBank,AAL22939,,,LT2,metJ,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,master repressor of the methionine regulon,,,methionine metabolism pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29866910,PubMed,10.1128/IAI.00429-18,Infect Immun. 2018 Aug 22;86(9). pii: e00429-18,dennis.ko@duke.edu,"The ΔmetJ mutant displayed reduced motility, host cell pyroptosis and invasion.",J S Bourgeois 2018,2018,2 genes,Bourgeois-2018-Methylthioadenosine suppresses,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13866,PHI:9083,UniProt,P06203,GenBank,AAL22939,,,LT2,metJ,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,master repressor of the methionine regulon,,,methionine metabolism pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29866910,PubMed,10.1128/IAI.00429-18,Infect Immun. 2018 Aug 22;86(9). pii: e00429-18,dennis.ko@duke.edu,"The ΔmetJ mutant displayed reduced motility, host cell pyroptosis and invasion.",J S Bourgeois 2018,2018,2 genes,Bourgeois-2018-Methylthioadenosine suppresses,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13867,PHI:9085,,no data found,,,,,,bbd01,,,,,,PHI:9086; PHI:9087,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13868,PHI:9086,,no data found,,,,,,bbd02,,,,,,PHI:9085; PHI:9087,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13869,PHI:9087,,no data found,,,,,,bbd03,,,,,,PHI:9085; PHI:9086,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13870,PHI:9085,,no data found,,,,,,bbd01,,,,,,PHI:9086; PHI:9087; PHI:9088; PHI:9089,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13871,PHI:9086,,no data found,,,,,,bbd02,,,,,,PHI:9085; PHI:9087; PHI:9088; PHI:9089,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13872,PHI:9087,,no data found,,,,,,bbd03,,,,,,PHI:9085; PHI:9086; PHI:9088; PHI:9089,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13873,PHI:9088,,no data found,,,,,,bbd04,,,,,,PHI:9085; PHI:9086; PHI:9087; PHI:9089,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13874,PHI:9089,,no data found,,,,,,bbd05,,,,,,PHI:9085; PHI:9086; PHI:9087; PHI:9088,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13875,PHI:9085,,no data found,,,,,,bbd01,,,,,,PHI:9086; PHI:9087; PHI:9088; PHI:9089; PHI:9090; PHI:9091,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13876,PHI:9086,,no data found,,,,,,bbd02,,,,,,PHI:9085; PHI:9087; PHI:9088; PHI:9089; PHI:9090; PHI:9091,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13877,PHI:9087,,no data found,,,,,,bbd03,,,,,,PHI:9085; PHI:9086; PHI:9088; PHI:9089; PHI:9090; PHI:9091,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13878,PHI:9088,,no data found,,,,,,bbd04,,,,,,PHI:9085; PHI:9086; PHI:9087; PHI:9089; PHI:9090; PHI:9091,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13879,PHI:9089,,no data found,,,,,,bbd05,,,,,,PHI:9085; PHI:9086; PHI:9087; PHI:9088; PHI:9090; PHI:9091,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13880,PHI:9090,,no data found,,,,,,bbd06,,,,,,PHI:9085; PHI:9086; PHI:9087; PHI:9088; PHI:9089; PHI:9091,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13881,PHI:9091,,no data found,,,,,,bbd07,,,,,,PHI:9085; PHI:9086; PHI:9087; PHI:9088; PHI:9089; PHI:9090,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; bladder; heart; blood; tibiotarsal joint,linear plasmid 17,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30945408,PubMed,10.1111/cmi.13029,Cell Microbiol. 2019 Apr 3:e13029,tbankhead@wsu.edu,Dissemination from the inoculation site to distal tissues was impaired for the mutant strain lacking bbd01-bbd07.,T Casselli 2019,2019,7 genes,Casselli-2019-A small intergenic region of lp1,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13882,PHI:9092,UniProt,Q8ZPS2,GenBank,AAL20275,,,LT2,ydiD,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),CBA,,,cecum,plant pathogenicity factor-like protein,,,anaerobic beta-oxidation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29447698,PubMed,10.1016/j.chom.2018.01.004,Cell Host Microbe. 2018 Feb 14;23(2):266-273.e4,ajbaumler@ucdavis.edu,Deletion of ydiD attenuated the ability of S. Typhimurium to trigger intestinal inflammation.,D N Bronner 2018,2018,2 genes,Bronner-2018-Genetic Ablation of Butyrate Util,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13883,PHI:9093,UniProt,Q8ZR36,GenBank,AAL19540,,,LT2,fepE,,phoN::viaB fepE,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),CBA,,,cecum,ferric enterobactin (enterochelin) transporter,,,anaerobic beta-oxidation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29447698,PubMed,10.1016/j.chom.2018.01.004,Cell Host Microbe. 2018 Feb 14;23(2):266-273.e4,ajbaumler@ucdavis.edu,Deletion of ydiD attenuated the ability of S. Typhimurium to trigger intestinal inflammation.,D N Bronner 2018,2018,2 genes,Bronner-2018-Genetic Ablation of Butyrate Util,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13884,PHI:9092,UniProt,Q8ZPS2,GenBank,AAL20275,,,LT2,ydiD,,,,,,PHI:9093,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),CBA,,,cecum,plant pathogenicity factor-like protein,,,anaerobic beta-oxidation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29447698,PubMed,10.1016/j.chom.2018.01.004,Cell Host Microbe. 2018 Feb 14;23(2):266-273.e4,ajbaumler@ucdavis.edu,Deletion of ydiD cooperated with inactivation of fepE and acquisition of viaB in moderating intestinal inflammation during typhoid fever.,D N Bronner 2018,2018,2 genes,Bronner-2018-Genetic Ablation of Butyrate Util,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13885,PHI:9093,UniProt,Q8ZR36,GenBank,AAL19540,,,LT2,fepE,,phoN::viaB fepE,,,,PHI:9092,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,rodents,10090,Mus musculus (related: house mouse),CBA,,,cecum,ferric enterobactin (enterochelin) transporter,,,anaerobic beta-oxidation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29447698,PubMed,10.1016/j.chom.2018.01.004,Cell Host Microbe. 2018 Feb 14;23(2):266-273.e4,ajbaumler@ucdavis.edu,Deletion of ydiD cooperated with inactivation of fepE and acquisition of viaB in moderating intestinal inflammation during typhoid fever.,D N Bronner 2018,2018,2 genes,Bronner-2018-Genetic Ablation of Butyrate Util,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13886,PHI:9094,UniProt,O02616,GenBank,AAC47549,,,,Fe-SODB,,,,,,,5693,Trypanosoma cruzi,1416333,Dm28c,Chagas disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood,iron superoxide dismutase B,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30979807,PubMed,10.1073/pnas.1821487116,Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8879-8888,rradi@fmed.edu.uy,T. cruzi cytosolic Fe-SODB overexpression exhibited higher resistance to macrophage-dependent killing and enhanced intracellular proliferation compared with wild-type (WT) parasites.,A Martínez 2019,2019,1 gene,Martinez-2019-Cytosolic Fe-superoxide dismutas,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13887,PHI:9094,UniProt,O02616,GenBank,AAC47549,,,,Fe-SODB,,,,,,,5693,Trypanosoma cruzi,1416333,Dm28c,Chagas disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,iron superoxide dismutase B,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30979807,PubMed,10.1073/pnas.1821487116,Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8879-8888,rradi@fmed.edu.uy,T. cruzi cytosolic Fe-SODB overexpression exhibited higher resistance to macrophage-dependent killing and enhanced intracellular proliferation compared with wild-type (WT) parasites.,A Martínez 2019,2019,1 gene,Martinez-2019-Cytosolic Fe-superoxide dismutas,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13888,PHI:9095,UniProt,I1S1A3,GenBank,CEF75937,,,PH-1,Fgvps60 (FGSG_10503),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,uncharacterized protein,,,DON biosynthesis,loss of pathogenicity,,,,,,reduced,reduced,reduced; aberrant,,no,calcofluor white (CFW); Congo red (CR); SDS; H2O2; KCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,30927052,PubMed,10.1007/s00294-019-00949-z,Curr Genet. 2019 Mar 29,wangzh@fafu.edu.cn,FgVps60 but not FgIst1 and FgDid2 is necessary for endocytosis.,Q Xie 2019,2019,3 genes,Xie-2019-ESCRT-III accessory proteins regulate,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13889,PHI:9096,UniProt,I1RMA7,GenBank,CEF85825,,,PH-1,Fgdid2 (FGSG_05094),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,uncharacterized protein,,,DON biosynthesis,loss of pathogenicity,,,,,,reduced,reduced,reduced; aberrant,,no,calcofluor white (CFW); Congo red (CR); SDS; H2O2; KCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,30927052,PubMed,10.1007/s00294-019-00949-z,Curr Genet. 2019 Mar 29,wangzh@fafu.edu.cn,"ΔFgvps60 and ΔFgdid2 but not ΔFgist1 also showed significant reduction in hydrophobicity on cell surface, conidiation, perithecia production and virulence.",Q Xie 2019,2019,3 genes,Xie-2019-ESCRT-III accessory proteins regulate,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13890,PHI:9097,UniProt,A0A0E0S1S6,GenBank,CEF77451,,,PH-1,Fgist1 (FGSG_12578),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,uncharacterized protein,,,DON biosynthesis,reduced virulence,,,,,,wild type,wild type,reduced; aberrant,,no,calcofluor white (CFW); Congo red (CR); SDS; H2O2; KCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,30927052,PubMed,10.1007/s00294-019-00949-z,Curr Genet. 2019 Mar 29,wangzh@fafu.edu.cn,ΔFgist1 mutant produced a significantly higher level of DON while showing a minor reduction in pathogenicity.,Q Xie 2019,2019,3 genes,Xie-2019-ESCRT-III accessory proteins regulate,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13891,PHI:9098,UniProt,A0A455ZLU4,GenBank,DAC76742,,,SF370,spnA,,ΔspnA::spnA_H716A,,,,,1314,Streptococcus pyogenes,,SF370,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cell wall-anchored nuclease A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29158081,PubMed,10.1016/j.jmii.2017.09.006,J Microbiol Immunol Infect. 2017 Nov 13. pii: S1684-1182(17)30236-0,t.proft@auckland.ac.nz,"GAS ΔspnA::spnA_H716A was less virulent than WT GAS, but has significantly higher virulence compared to GAS ΔspnA::spnA.",C Chalmers 2017,2017,1 gene,Chalmers-2017-Streptococcus pyogenes nuclease,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13892,PHI:9098,UniProt,A0A455ZLU4,GenBank,DAC76742,,,SF370,spnA,,,,,,,1314,Streptococcus pyogenes,,SF370,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cell wall-anchored nuclease A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29158081,PubMed,10.1016/j.jmii.2017.09.006,J Microbiol Immunol Infect. 2017 Nov 13. pii: S1684-1182(17)30236-0,t.proft@auckland.ac.nz,"GAS ΔspnA::spnA_H716A was less virulent than WT GAS, but has significantly higher virulence compared to GAS ΔspnA::spnA.",C Chalmers 2017,2017,1 gene,Chalmers-2017-Streptococcus pyogenes nuclease,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13893,PHI:9099,,no data found,GenBank,QBR98154,,,DAPP-PG722,cneA,,,,,,,29438,Pseudomonas savastanoi,,pv. savastanoi strain DAPP-PG 722,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,leaf,Na+/Ca2+ exchanger,,,,reduced virulence,,,,,,,,,,no,nifedipine; LiCl,nifedipine: CHEBI:7565; LiCl: CHEBI:48607,,,,,gene deletion: full; gene complementation,,,YVS,30912619,PubMed,10.1111/mpp.12787,Mol Plant Pathol. 2019 May;20(5):716-730,chiaraluce.moretti@unipg.it,"Mutation of cneA compromised not only Ca2+ entry, but also compromised the Hypersensitive response (HR) in tobacco leaves and blocked the ability to induce knots in olive stems.",C Moretti 2019,2019,1 gene,Moretti-2019-A Na(+) _Ca(2+) exchanger of the,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13894,PHI:9099,,no data found,GenBank,QBR98154,,,DAPP-PG722,cneA,,,,,,,29438,Pseudomonas savastanoi,,pv. savastanoi strain DAPP-PG 722,knot (olive),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Havana 425,,,leaf,Na+/Ca2+ exchanger,,,,reduced virulence,,,,,,,,,,no,nifedipine; LiCl,nifedipine: CHEBI:7565; LiCl: CHEBI:48607,,,,,gene deletion: full; gene complementation,,,YVS,30912619,PubMed,10.1111/mpp.12787,Mol Plant Pathol. 2019 May;20(5):716-730,chiaraluce.moretti@unipg.it,"Mutation of cneA compromised not only Ca2+ entry, but also compromised the Hypersensitive response (HR) in tobacco leaves and blocked the ability to induce knots in olive stems.",C Moretti 2019,2019,1 gene,Moretti-2019-A Na(+) _Ca(2+) exchanger of the,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13895,PHI:9100,UniProt,G4NE57,GenBank,EHA49386,,,70-15,Mopex13 (MGG_00157),chromosome 5,,,Mopex5; Mopex7; Mopex14,UniProt: G4MYV5; GenBank: EHA53616; UniProt: G4MSX7; GenBank: EHA54636; UniProt: G4NCT7; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,peroxisomal membrane protein,,,,loss of pathogenicity,,no,yes,yes,,reduced,reduced,reduced; aberrant,reduced,no,H2O2; methyl viologen; rose bengal; Congo red (CR); calcofluor white (CFW),H2O2: CHEBI:16240; methyl viologen: CHEBI:28786; rose bengal: CHEBI:52261; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,30905264,PubMed,10.1080/21505594.2019.1598172,Virulence. 2019 Dec;10(1):292-314,sungc01@sina.com,The infection failures in Δmopex13 and Δmopex14 were also due to their reduced ability to degrade fatty acids and to endure reactive oxygen species and cell wall-disrupting compounds.,J Y Wang 2019,2019,2 genes,"Wang-2019-Pex13 and Pex14, the key components",BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13896,PHI:9101,UniProt,G4NCT7,GenBank,EHA48330,,,70-15,Mopex14 (MGG_01028),chromosome 5,,,Mopex5; Mopex7; Mopex13; Mopex14; Mopex14/17 (pex33),UniProt: G4MYV5; GenBank: EHA53616; UniProt: G4MSX7; GenBank: EHA54636; UniProt: G4NE57; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,loss of pathogenicity,,no,yes,yes,,reduced,reduced,reduced; aberrant,reduced,no,H2O2; methyl viologen; rose bengal; Congo red (CR); calcofluor white (CFW),H2O2: CHEBI:16240; methyl viologen: CHEBI:28786; rose bengal: CHEBI:52261; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,30905264,PubMed,10.1080/21505594.2019.1598172,Virulence. 2019 Dec;10(1):292-314,sungc01@sina.com,The infection failures in Δmopex13 and Δmopex14 were also due to their reduced ability to degrade fatty acids and to endure reactive oxygen species and cell wall-disrupting compounds.,J Y Wang 2019,2019,2 genes,"Wang-2019-Pex13 and Pex14, the key components",BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13897,PHI:9100,UniProt,G4NE57,GenBank,EHA49386,,,70-15,Mopex13 (MGG_00157),chromosome 5,,,Mopex5; Mopex7; Mopex14,UniProt: G4MYV5; GenBank: EHA53616; UniProt: G4MSX7; GenBank: EHA54636; UniProt: G4NCT7; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,peroxisomal membrane protein,,,,loss of pathogenicity,,no,yes,yes,,reduced,reduced,reduced; aberrant,reduced,no,H2O2; methyl viologen; rose bengal; Congo red (CR); calcofluor white (CFW),H2O2: CHEBI:16240; methyl viologen: CHEBI:28786; rose bengal: CHEBI:52261; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,30905264,PubMed,10.1080/21505594.2019.1598172,Virulence. 2019 Dec;10(1):292-314,sungc01@sina.com,The infection failures in Δmopex13 and Δmopex14 were also due to their reduced ability to degrade fatty acids and to endure reactive oxygen species and cell wall-disrupting compounds.,J Y Wang 2019,2019,2 genes,"Wang-2019-Pex13 and Pex14, the key components",BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13898,PHI:9101,UniProt,G4NCT7,GenBank,EHA48330,,,70-15,Mopex14 (MGG_01028),chromosome 5,,,Mopex5; Mopex7; Mopex13; Mopex14; Mopex14/17 (pex33),UniProt: G4MYV5; GenBank: EHA53616; UniProt: G4MSX7; GenBank: EHA54636; UniProt: G4NE57; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,hypothetical protein,,,,loss of pathogenicity,,no,yes,yes,,reduced,reduced,reduced; aberrant,reduced,no,H2O2; methyl viologen; rose bengal; Congo red (CR); calcofluor white (CFW),H2O2: CHEBI:16240; methyl viologen: CHEBI:28786; rose bengal: CHEBI:52261; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,30905264,PubMed,10.1080/21505594.2019.1598172,Virulence. 2019 Dec;10(1):292-314,sungc01@sina.com,The infection failures in Δmopex13 and Δmopex14 were also due to their reduced ability to degrade fatty acids and to endure reactive oxygen species and cell wall-disrupting compounds.,J Y Wang 2019,2019,2 genes,"Wang-2019-Pex13 and Pex14, the key components",BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13899,PHI:9102,UniProt,J5JQG0,GenBank,EJP65091,,,ARSEF 2860,BbRei1 (BBA_05861),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cytoplasm-specific pre-60S subunit export factor,,,,reduced virulence,,,yes,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30932324,PubMed,10.1111/1462-2920.14616,Environ Microbiol. 2019 Apr 1,mgfeng@zju.edu.cn,"In ΔBbrei1, greatly attenuated virulence correlated with reduced activities of enzymes secreted for cuticular penetration and blocked formation of hyphal bodies in vivoessential for facilitation of host mummification.",W Shao 2019,2019,1 gene,Shao-2019-Rei1-like protein regulates nutritio,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13900,PHI:9103,UniProt,I1RUA7,GenBank,CEF82868,,,PH-1,FGRRES_07792,chromosome 4,,,,,,5518,Fusarium graminearum,,3827,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite,,,spikelet,class X G-protein coupled receptor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30934025,PubMed,10.1371/journal.ppat.1007666,PLoS Pathog. 2019 Apr 1;15(4):e1007666,n.a.brown@bath.ac.uk,"Class X receptors FGRRES_07792 and FGRRES_16221 were involved in virulence, but were not essential for DON production",T Dilks 2019,2019,2 genes,Dilks-2019-Non-canonical fungal G-protein coup,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13901,PHI:9104,UniProt,A0A0E0S4Y5,GenBank,CEF78560,,,PH-1,FGRRES_16221,chromosome 2,,,,,,5518,Fusarium graminearum,,3827,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Landsberg erecta,,,inflorescence,class X G-protein coupled receptor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30934025,PubMed,10.1371/journal.ppat.1007666,PLoS Pathog. 2019 Apr 1;15(4):e1007666,n.a.brown@bath.ac.uk,"Class X receptors FGRRES_07792 and FGRRES_16221 were involved in virulence, but were not essential for DON production",T Dilks 2019,2019,2 genes,Dilks-2019-Non-canonical fungal G-protein coup,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13902,PHI:9105,UniProt,A0A0B6E6Q6,GenBank,AJI50601,,,FTT_1,silC (FTL_0686),,,,,,,263,Francisella tularensis,376619,subsp. holarctica strain LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,outer membrane efflux family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29378894,PubMed,10.1128/JB.00693-17,J Bacteriol. 2018 Mar 26;200(8). pii: e00693-17,Shekhar_Bakshi@nymc.edu,"The ΔsilC mutant exhibited increased sensitivity to antibiotics, oxidants, silver, diminished intramacrophage growth, and attenuated virulence in mice compared to wild-type F. tularensis",M Alqahtani 2018,2018,1 gene,Alqahtani-2018-Characterization of a Unique Ou,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13903,PHI:9105,UniProt,A0A0B6E6Q6,GenBank,AJI50601,,,FTT_1,silC (FTL_0686),,,,,,,263,Francisella tularensis,376619,subsp. holarctica strain LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),gp91phox<-/->,,,,outer membrane efflux family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29378894,PubMed,10.1128/JB.00693-17,J Bacteriol. 2018 Mar 26;200(8). pii: e00693-17,Shekhar_Bakshi@nymc.edu,"The ΔsilC mutant exhibited increased sensitivity to antibiotics, oxidants, silver, diminished intramacrophage growth, and attenuated virulence in mice compared to wild-type F. tularensis",M Alqahtani 2018,2018,1 gene,Alqahtani-2018-Characterization of a Unique Ou,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13904,PHI:9105,UniProt,A0A0B6E6Q6,GenBank,AJI50601,,,FTT_1,silC (FTL_0686),,,,,,,263,Francisella tularensis,376619,subsp. holarctica strain LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane efflux family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29378894,PubMed,10.1128/JB.00693-17,J Bacteriol. 2018 Mar 26;200(8). pii: e00693-17,Shekhar_Bakshi@nymc.edu,"The ΔsilC mutant exhibited increased sensitivity to antibiotics, oxidants, silver, diminished intramacrophage growth, and attenuated virulence in mice compared to wild-type F. tularensis",M Alqahtani 2018,2018,1 gene,Alqahtani-2018-Characterization of a Unique Ou,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13905,PHI:9106,UniProt,I6ZFI8,GenBank,AFN68300,,,ATCC 66981,PksI,,,,,,,5599,Alternaria alternata,,ATCC 66981,brown spot,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30947377,PubMed,10.1111/mmi.14258,Mol Microbiol. 2019 Apr 4,reinhard.fischer@KIT.edu,"The pksI-deletion strain displayed reduced virulence on tomato, citrus and apple suggesting AOH and the derivatives as virulence and colonization factors.",M Wenderoth 2019,2019,1 gene,Wenderoth-2019-Alternariol as virulence and co,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13906,PHI:9106,UniProt,I6ZFI8,GenBank,AFN68300,,,ATCC 66981,PksI,,,,,,,5599,Alternaria alternata,,ATCC 66981,brown spot,eudicots,3750,Malus domestica (related: apple),,,,fruit,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30947377,PubMed,10.1111/mmi.14258,Mol Microbiol. 2019 Apr 4,reinhard.fischer@KIT.edu,"The pksI-deletion strain displayed reduced virulence on tomato, citrus and apple suggesting AOH and the derivatives as virulence and colonization factors.",M Wenderoth 2019,2019,1 gene,Wenderoth-2019-Alternariol as virulence and co,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13907,PHI:9106,UniProt,I6ZFI8,GenBank,AFN68300,,,ATCC 66981,PksI,,,,,,,5599,Alternaria alternata,,ATCC 66981,brown spot,eudicots,2706,Citrus (no common name found),,,,fruit,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30947377,PubMed,10.1111/mmi.14258,Mol Microbiol. 2019 Apr 4,reinhard.fischer@KIT.edu,"The pksI-deletion strain displayed reduced virulence on tomato, citrus and apple suggesting AOH and the derivatives as virulence and colonization factors.",M Wenderoth 2019,2019,1 gene,Wenderoth-2019-Alternariol as virulence and co,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13908,PHI:9107,UniProt,Q663K1,GenBank,CAA36129,,,"YPIII/pIB1, serotype III",YopN,,YopNΔ76-181,,,,,633,Yersinia pseudotuberculosis,,YPIII/pIB102,zoonotic infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29760214,PubMed,10.1128/IAI.00957-17,Infect Immun. 2018 Jul 23;86(8). pii: e00957-17,ake.forsberg@umu.se,YopN deletion mutant lost its ability to block phagocytosis by macrophages.,S Bamyaci 2018,2018,2 genes,Bamyaci-2018-YopN is required for efficient ef,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13909,PHI:9107,UniProt,Q663K1,GenBank,CAA36129,,,"YPIII/pIB1, serotype III",YopN,,YopNΔ131-167,,,,,633,Yersinia pseudotuberculosis,,YPIII/pIB102,zoonotic infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29760214,PubMed,10.1128/IAI.00957-17,Infect Immun. 2018 Jul 23;86(8). pii: e00957-17,ake.forsberg@umu.se,YopN deletion mutant lost its ability to block phagocytosis by macrophages.,S Bamyaci 2018,2018,2 genes,Bamyaci-2018-YopN is required for efficient ef,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13910,PHI:9107,UniProt,Q663K1,GenBank,CAA36129,,,"YPIII/pIB1, serotype III",YopN,,YopNΔ170-207,,,,,633,Yersinia pseudotuberculosis,,YPIII/pIB102,zoonotic infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29760214,PubMed,10.1128/IAI.00957-17,Infect Immun. 2018 Jul 23;86(8). pii: e00957-17,ake.forsberg@umu.se,YopN deletion mutant lost its ability to block phagocytosis by macrophages.,S Bamyaci 2018,2018,2 genes,Bamyaci-2018-YopN is required for efficient ef,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13911,PHI:9108,UniProt,P23994,GenBank,AAA27645,,,YPIII(pIB1),lcrV,,,,,,,633,Yersinia pseudotuberculosis,,YPIII/pIB102,zoonotic infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,virulence-associated V antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29760214,PubMed,10.1128/IAI.00957-17,Infect Immun. 2018 Jul 23;86(8). pii: e00957-17,ake.forsberg@umu.se,LcrV deletion mutant lost its ability to block phagocytosis by macrophages.,S Bamyaci 2018,2018,2 genes,Bamyaci-2018-YopN is required for efficient ef,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13912,PHI:9107,UniProt,Q663K1,GenBank,CAA36129,,,"YPIII/pIB1, serotype III",YopN,,YopNΔ76-181,,,,,633,Yersinia pseudotuberculosis,,YPIII/pIB102,zoonotic infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29760214,PubMed,10.1128/IAI.00957-17,Infect Immun. 2018 Jul 23;86(8). pii: e00957-17,ake.forsberg@umu.se,YopN deletion variants displayed delayed cytotoxicity in HeLa cells.,S Bamyaci 2018,2018,2 genes,Bamyaci-2018-YopN is required for efficient ef,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13913,PHI:9107,UniProt,Q663K1,GenBank,CAA36129,,,"YPIII/pIB1, serotype III",YopN,,YopNΔ131-167,,,,,633,Yersinia pseudotuberculosis,,YPIII/pIB102,zoonotic infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29760214,PubMed,10.1128/IAI.00957-17,Infect Immun. 2018 Jul 23;86(8). pii: e00957-17,ake.forsberg@umu.se,YopN deletion variants displayed delayed cytotoxicity in HeLa cells.,S Bamyaci 2018,2018,2 genes,Bamyaci-2018-YopN is required for efficient ef,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13914,PHI:9107,UniProt,Q663K1,GenBank,CAA36129,,,"YPIII/pIB1, serotype III",YopN,,YopNΔ170-207,,,,,633,Yersinia pseudotuberculosis,,YPIII/pIB102,zoonotic infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,29760214,PubMed,10.1128/IAI.00957-17,Infect Immun. 2018 Jul 23;86(8). pii: e00957-17,ake.forsberg@umu.se,YopN deletion variants displayed delayed cytotoxicity in HeLa cells.,S Bamyaci 2018,2018,2 genes,Bamyaci-2018-YopN is required for efficient ef,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13915,PHI:9109,UniProt,E3QSY2,GenBank,GLRG09114,,,,Cgtrpf1,,,,,,,31870,Colletotrichum graminicola,,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Golden Jubilee,,,leaf,transient receptor potential (TRP) channel family protein,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,27359114,PubMed,10.1371/journal.pone.0158561,PLoS One. 2016 Jun 30;11(6):e0158561,edgar.peiter@landw.uni-halle.de,"Deletion strains for the CgTRPF genes were not altered in processes thought to involve Ca2+ release from internal stores, i.e. spore germination, the utilization of complex carbon sources, and the generation of tip-focussed [Ca2+]cyt spikes.",M Lange 2016,2016,4 genes,Lange-2016-The Transient Receptor Potential (T,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13916,PHI:9110,UniProt,E3QXS6,GenBank,GLRG10771,,,,Cgtrpf2,,,,,,,31870,Colletotrichum graminicola,,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Golden Jubilee,,,leaf,transient receptor potential (TRP) channel family protein,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,27359114,PubMed,10.1371/journal.pone.0158561,PLoS One. 2016 Jun 30;11(6):e0158561,edgar.peiter@landw.uni-halle.de,"Deletion strains for the CgTRPF genes were not altered in processes thought to involve Ca2+ release from internal stores, i.e. spore germination, the utilization of complex carbon sources, and the generation of tip-focussed [Ca2+]cyt spikes.",M Lange 2016,2016,4 genes,Lange-2016-The Transient Receptor Potential (T,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13917,PHI:9111,UniProt,E3QQT6,GenBank,GLRG08368,,,,Cgtrpf3,,,,,,,31870,Colletotrichum graminicola,,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Golden Jubilee,,,leaf,transient receptor potential (TRP) channel family protein,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,27359114,PubMed,10.1371/journal.pone.0158561,PLoS One. 2016 Jun 30;11(6):e0158561,edgar.peiter@landw.uni-halle.de,"Deletion strains for the CgTRPF genes were not altered in processes thought to involve Ca2+ release from internal stores, i.e. spore germination, the utilization of complex carbon sources, and the generation of tip-focussed [Ca2+]cyt spikes.",M Lange 2016,2016,4 genes,Lange-2016-The Transient Receptor Potential (T,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13918,PHI:9112,UniProt,E3QV14,GenBank,GLRG09848,,,,Cgtrpf4,,,,,,,31870,Colletotrichum graminicola,,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Golden Jubilee,,,leaf,transient receptor potential (TRP) channel family protein,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,27359114,PubMed,10.1371/journal.pone.0158561,PLoS One. 2016 Jun 30;11(6):e0158561,edgar.peiter@landw.uni-halle.de,"Deletion strains for the CgTRPF genes were not altered in processes thought to involve Ca2+ release from internal stores, i.e. spore germination, the utilization of complex carbon sources, and the generation of tip-focussed [Ca2+]cyt spikes.",M Lange 2016,2016,4 genes,Lange-2016-The Transient Receptor Potential (T,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13919,PHI:9113,UniProt,Q8GM84,GenBank,AAL25250,,,5055,rcsB,,,,,,,573,Klebsiella pneumoniae,,KPPR1S,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,transcriptional regulator of capsule synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30914502,PubMed,10.1128/mBio.00089-19,MBio. 2019 Mar 26;10(2). pii: e00089-19,kawalker@med.unc.edu,The ΔrmpA and ΔrcsB strains showed between 5 to 8-fold increases in host-cell associations compared to KPPR1S.,K A Walker 2019,2019,3 genes,Walker-2019-A Klebsiella pneumoniae Regulatory,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13920,PHI:9114,UniProt,Q8GM81,GenBank,AAL25252,,,5055,rmpA,,,,,,,573,Klebsiella pneumoniae,,KPPR1S,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,regulator of mucoid phenotype,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30914502,PubMed,10.1128/mBio.00089-19,MBio. 2019 Mar 26;10(2). pii: e00089-19,kawalker@med.unc.edu,The ΔrmpA and ΔrcsB strains showed between 5 to 8-fold increases in host-cell associations compared to KPPR1S.,K A Walker 2019,2019,3 genes,Walker-2019-A Klebsiella pneumoniae Regulatory,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13921,PHI:9115,,no data found,GenBank,AIK83625,,,,rmpC,,,,,,,573,Klebsiella pneumoniae,,KPPR1S,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; spleen,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30914502,PubMed,10.1128/mBio.00089-19,MBio. 2019 Mar 26;10(2). pii: e00089-19,kawalker@med.unc.edu,The ΔrmpC strain exhibited a wild-type-like phenotype with very low adherence at 3%.,K A Walker 2019,2019,3 genes,Walker-2019-A Klebsiella pneumoniae Regulatory,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13922,PHI:9116,UniProt,E3QI14,GenBank,EFQ30502,,,M1.001,GLS1,,,,,,,31870,Colletotrichum graminicola,,M2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Nathan,,,leaf,"β-1,3-glucan synthase",,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,23898035,PubMed,10.1105/tpc.112.103499,Plant Cell. 2013 Jun;25(6):2356-78,holger.deising@landw.uni-halle.de,"Although β-1,3-glucan synthesis was required for cell wall rigidity in appressoria and fast-growing necrotrophic hyphae, constitutive expression of GLS1 led to exposure of β-1,3-glucan on biotrophic hyphae, massive induction of broad-spectrum defense responses and significantly reduced disease symptom severity.",E Oliveira-Garcia 2013,2013,1 gene,Oliveira-Garcia-2013-Infection structure-speci,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13923,PHI:9117,UniProt,D0CEJ1,GenBank,EEX02051,,,ATCC 19606,TonB-dependent copper receptor,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,"TonB-dependent copper receptor, outer membraneprotein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29505819,PubMed,10.1016/j.meegid.2018.03.001,Infect Genet Evol. 2018 Jun;60:181-190,rasooli@shahed.ac.ir,"Deletion of this gene led to cessation in biofilm formation, adherence, hydrophobicity, resistance to human sera and in vivo dissemination of the bacterium.",S Abdollahi 2018,2018,1 gene,Abdollahi-2018-The role of TonB-dependent copp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13924,PHI:9117,UniProt,D0CEJ1,GenBank,EEX02051,,,ATCC 19606,TonB-dependent copper receptor,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"TonB-dependent copper receptor, outer membraneprotein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,29505819,PubMed,10.1016/j.meegid.2018.03.001,Infect Genet Evol. 2018 Jun;60:181-190,rasooli@shahed.ac.ir,TonB-dependent copper receptor played a major role in adherence of A. baumannii to epithelial cells.,S Abdollahi 2018,2018,1 gene,Abdollahi-2018-The role of TonB-dependent copp,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13925,PHI:9118,UniProt,Q8PI46,GenBank,AAM37897,,,306,TfmR (XAC3052),,Xcc XAC3052:Tn5,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruit,"TetR-family transcriptional regulator, T3SS and fatty acid mechanism regulator",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,30919570,PubMed,10.1111/mpp.12786,Mol Plant Pathol. 2019 May;20(5):701-715,nianwang@ufl.edu,XccΔtfmR showed significant reduction in motility and production of exopolysaccharides (EPS).,D Teper 2019,2019,2 genes,"Teper-2019-TfmR, a novel TetR-family transcrip",BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13926,PHI:9118,UniProt,Q8PI46,GenBank,AAM37897,,,306,TfmR (XAC3052),,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruit,"TetR-family transcriptional regulator, T3SS and fatty acid mechanism regulator",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30919570,PubMed,10.1111/mpp.12786,Mol Plant Pathol. 2019 May;20(5):701-715,nianwang@ufl.edu,XccΔtfmR showed significant reduction in motility and production of exopolysaccharides (EPS).,D Teper 2019,2019,2 genes,"Teper-2019-TfmR, a novel TetR-family transcrip",BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13927,PHI:9118,UniProt,Q8PI46,GenBank,AAM37897,,,306,TfmR (XAC3052),,,,,,PHI:9119,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruit,"TetR-family transcriptional regulator, T3SS and fatty acid mechanism regulator",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30919570,PubMed,10.1111/mpp.12786,Mol Plant Pathol. 2019 May;20(5):701-715,nianwang@ufl.edu,"Overexpression of hrpG restored the virulence of ΔXAC3052, suggesting that the loss of virulence is caused by reduction of T3SS gene expression.",D Teper 2019,2019,2 genes,"Teper-2019-TfmR, a novel TetR-family transcrip",BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13928,PHI:9119,UniProt,Q8PN09,GenBank,AAM36136,,,306,HrpG,,,,,,PHI:9118,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruit,master transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30919570,PubMed,10.1111/mpp.12786,Mol Plant Pathol. 2019 May;20(5):701-715,nianwang@ufl.edu,"Overexpression of hrpG restored the virulence of ΔXAC3052, suggesting that the loss of virulence is caused by reduction of T3SS gene expression.",D Teper 2019,2019,2 genes,"Teper-2019-TfmR, a novel TetR-family transcrip",BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13929,PHI:9120,UniProt,Q1JJJ3,GenBank,ABF32980,,,MGAS9429,PepO,,,,,,,1314,Streptococcus pyogenes,,5448,infection,rodents,10090,Mus musculus (related: house mouse),AlbPLG1<+/->,,,,endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29378883,PubMed,10.1128/JB.00654-17,J Bacteriol. 2018 Mar 26;200(8). pii: e00654-17,mark.walker@uq.edu.au,5448ΔpepO mutant strain is more susceptible to killing by human neutrophils and is attenuated in virulence in a murine model of invasiveGAS infection.,S Brouwer 2018,2018,1 gene,Brouwer-2018-The endopeptidase PepO regulates,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13930,PHI:9120,UniProt,Q1JJJ3,GenBank,ABF32980,,,MGAS9429,PepO,,,,,,,1314,Streptococcus pyogenes,,5448,infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29378883,PubMed,10.1128/JB.00654-17,J Bacteriol. 2018 Mar 26;200(8). pii: e00654-17,mark.walker@uq.edu.au,5448ΔpepO mutant strain is more susceptible to killing by human neutrophils and is attenuated in virulence in a murine model of invasiveGAS infection.,S Brouwer 2018,2018,1 gene,Brouwer-2018-The endopeptidase PepO regulates,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13931,PHI:9121,UniProt,J5JMW3,GenBank,EJP64381,,,ARSEF 2860,Bbmcm1 (BBA_06763),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MADS-box transcription factor,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,30972885,PubMed,10.1111/1462-2920.14629,Environ Microbiol. 2019 Apr 10,yjzhang@swu.edu.cn,"ΔBbmcm1 displayed impaired cell integrity, with distorted cell wall structure and altered cell wall component.",X Zhao 2019,2019,1 gene,Zhao-2019-MADS-box transcription factor Mcm1 c,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13932,PHI:9122,UniProt,P0AD45,GenBank,AE005485_7,,,EDL933,qseG,,,,SepL,UniProt: Q7DB79; GenBank: ACG59619,,562,Escherichia coli,,86-24,urinary tract infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,colon,"outer membrane lipoprotein, quorum sensing regulator",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29358334,PubMed,10.1128/IAI.00936-17,Infect Immun. 2018 Mar 22;86(4). pii: e00936-17,vanessa.sperandio@utsouthwestern.edu,EHEC ΔqseG mutant had reduced intestinal colonization in an infant rabbit model.,E A Cameron 2018,2018,3 genes,Cameron-2018-The QseG lipoprotein impacts the,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13933,PHI:9123,UniProt,D2TU09,GenBank,CBG89241,,,ICC168,qseG,,,,,,,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,colon,"outer membrane lipoprotein, quorum sensing regulator",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29358334,PubMed,10.1128/IAI.00936-17,Infect Immun. 2018 Mar 22;86(4). pii: e00936-17,vanessa.sperandio@utsouthwestern.edu,"In Citrobacter rodentium, an AE lesion-forming pathogen like EHEC, QseG is required for full virulence in a mouse model.",E A Cameron 2018,2018,3 genes,Cameron-2018-The QseG lipoprotein impacts the,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13934,PHI:9124,UniProt,A0A0U1H4M7,GenBank,CNR35847,,,CH43,qseG,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,"outer membrane lipoprotein, quorum sensing regulator",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29358334,PubMed,10.1128/IAI.00936-17,Infect Immun. 2018 Mar 22;86(4). pii: e00936-17,vanessa.sperandio@utsouthwestern.edu,S Typhimurium ΔqseG mutant caused a more severe inflammatory response and was attenuated versus the wild-type strain.,E A Cameron 2018,2018,3 genes,Cameron-2018-The QseG lipoprotein impacts the,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13935,PHI:9124,UniProt,A0A0U1H4M7,GenBank,CNR35847,,,CH43,qseG,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,colitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,"outer membrane lipoprotein, quorum sensing regulator",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29358334,PubMed,10.1128/IAI.00936-17,Infect Immun. 2018 Mar 22;86(4). pii: e00936-17,vanessa.sperandio@utsouthwestern.edu,"Absence of qseG did not affect S. Typhimurium motility, cell invasion, or intracellular replication in infection of tissue-cultured cells but provoked increased inflammatory cytokine production versus the wild type in T84 colonic epithelial cells.",E A Cameron 2018,2018,3 genes,Cameron-2018-The QseG lipoprotein impacts the,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13936,PHI:9124,UniProt,A0A0U1H4M7,GenBank,CNR35847,,,CH43,qseG,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,colitis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,"outer membrane lipoprotein, quorum sensing regulator",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29358334,PubMed,10.1128/IAI.00936-17,Infect Immun. 2018 Mar 22;86(4). pii: e00936-17,vanessa.sperandio@utsouthwestern.edu,"Absence of qseG did not affect S. Typhimurium motility, cell invasion, or intracellular replication in infection of tissue-cultured cells but provoked increased inflammatory cytokine production versus the wild type in T84 colonic epithelial cells.",E A Cameron 2018,2018,3 genes,Cameron-2018-The QseG lipoprotein impacts the,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13937,PHI:9124,UniProt,A0A0U1H4M7,GenBank,CNR35847,,,CH43,qseG,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,colitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,"outer membrane lipoprotein, quorum sensing regulator",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29358334,PubMed,10.1128/IAI.00936-17,Infect Immun. 2018 Mar 22;86(4). pii: e00936-17,vanessa.sperandio@utsouthwestern.edu,"Absence of qseG did not affect S. Typhimurium motility, cell invasion, or intracellular replication in infection of tissue-cultured cells but provoked increased inflammatory cytokine production versus the wild type in T84 colonic epithelial cells.",E A Cameron 2018,2018,3 genes,Cameron-2018-The QseG lipoprotein impacts the,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13938,PHI:9125,UniProt,Q2YQS6,GenBank,CAJ12112,,,2308,ybeY (bab1_2156),chromosome I,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage; spleen,endoribonuclease,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,"deoxycholate; polymyxin B; hydrogen peroxide; SDS; paraquat; dodecyltrimethyl ammonium bromide; promethazine; alexidine; dichlofluanid; chloroxylenol; sodium m-periodate; lidocaine; josamycin; thioridazine; patulin; tetrazolium violet; fusaric acid; 1-chloro-2,4-dinitrobenzene; 2-phenylphenol; antimony (III) chloride; pentachloro-phenol; azathioprine; phenethicillin; lawsone","deoxycholate: CHEBI:23614; polymyxin B: CHEBI:8309; hydrogen peroxide: CHEBI:16240; SDS: CHEBI:8984; paraquat: CHEBI:34905; dodecyltrimethyl ammonium bromide: CHEBI:282662; promethazine: CHEBI:8461; alexidine: CHEBI:53661; dichlofluanid: CHEBI:74875; chloroxylenol: CHEBI:34393; sodium m-periodate: CHEBI:75226; lidocaine: CHEBI:6456; josamycin: CHEBI:31739; thioridazine: CHEBI:9566; patulin: CHEBI:74926; tetrazolium violet: CHEBI:75193; fusaric acid: CHEBI:5199; 1-chloro-2,4-dinitrobenzene: CHEBI:34718; 2-phenylphenol: CHEBI:17043; antimony (III) chloride: CHEBI:74856; pentachloro-phenol: CHEBI:17642; azathioprine: CHEBI:2948; phenethicillin: CHEBI:52427; lawsone: CHEBI:44401",,,,,gene disruption; gene complementation,,,YVS,29632093,PubMed,10.1128/JB.00105-18,J Bacteriol. 2018 May 24;200(12). pii: e00105-18,caswellc@vt.edu,YbeY was necessary for the ability of B. abortus to sustain infection in macrophages and mice.,J A Budnick 2018,2018,10 genes,Budnick-2018-The endoribonuclease YbeY is link,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13939,PHI:9126,UniProt,Q2YIV2,GenBank,CAJ12443,,,2308,bab2_0277,chromosome II,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,choline dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29632093,PubMed,10.1128/JB.00105-18,J Bacteriol. 2018 May 24;200(12). pii: e00105-18,caswellc@vt.edu,"Mutants Δbab2_0822, Δbab2_1109 and Δbab2_0700 were less able to survive and replicate in the macrophages than parental strain 2308 at 48 h postinfection, while the other deletion strains displayed wild-type levels of infection.",J A Budnick 2018,2018,10 genes,Budnick-2018-The endoribonuclease YbeY is link,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13940,PHI:9127,UniProt,Q2YLB9,GenBank,CAJ12448,,,2308,bab2_0282,chromosome II,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,ABC transporter permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29632093,PubMed,10.1128/JB.00105-18,J Bacteriol. 2018 May 24;200(12). pii: e00105-18,caswellc@vt.edu,"Mutants Δbab2_0822, Δbab2_1109 and Δbab2_0700 were less able to survive and replicate in the macrophages than parental strain 2308 at 48 h postinfection, while the other deletion strains displayed wild-type levels of infection.",J A Budnick 2018,2018,10 genes,Budnick-2018-The endoribonuclease YbeY is link,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13941,PHI:9128,UniProt,Q2YK58,GenBank,CAJ12988,,,2308,bab2_0822,chromosome II,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,ABC transporter periplasmic binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29632093,PubMed,10.1128/JB.00105-18,J Bacteriol. 2018 May 24;200(12). pii: e00105-18,caswellc@vt.edu,"Mutants Δbab2_0822, Δbab2_1109 and Δbab2_0700 were less able to survive and replicate in the macrophages than parental strain 2308 at 48 h postinfection, while the other deletion strains displayed wild-type levels of infection.",J A Budnick 2018,2018,10 genes,Budnick-2018-The endoribonuclease YbeY is link,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13942,PHI:9129,UniProt,Q2YJE8,GenBank,CAJ13275,,,2308,bab2_1109,chromosome II,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,ABC transporter periplasmic binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29632093,PubMed,10.1128/JB.00105-18,J Bacteriol. 2018 May 24;200(12). pii: e00105-18,caswellc@vt.edu,"Mutants Δbab2_0822, Δbab2_1109 and Δbab2_0700 were less able to survive and replicate in the macrophages than parental strain 2308 at 48 h postinfection, while the other deletion strains displayed wild-type levels of infection.",J A Budnick 2018,2018,10 genes,Budnick-2018-The endoribonuclease YbeY is link,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13943,PHI:9130,UniProt,Q2YKG0,GenBank,CAJ12866,,,2308,bab2_0700,chromosome II,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,ABC transporter periplasmic binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29632093,PubMed,10.1128/JB.00105-18,J Bacteriol. 2018 May 24;200(12). pii: e00105-18,caswellc@vt.edu,"Mutants Δbab2_0822, Δbab2_1109 and Δbab2_0700 were less able to survive and replicate in the macrophages than parental strain 2308 at 48 h postinfection, while the other deletion strains displayed wild-type levels of infection.",J A Budnick 2018,2018,10 genes,Budnick-2018-The endoribonuclease YbeY is link,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13944,PHI:9131,UniProt,Q2YKU8,GenBank,CAJ12714,,,2308,bab2_0548,chromosome II,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,ABC transporter permease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29632093,PubMed,10.1128/JB.00105-18,J Bacteriol. 2018 May 24;200(12). pii: e00105-18,caswellc@vt.edu,"Mutants Δbab2_0822, Δbab2_1109 and Δbab2_0700 were less able to survive and replicate in the macrophages than parental strain 2308 at 48 h postinfection, while the other deletion strains displayed wild-type levels of infection.",J A Budnick 2018,2018,10 genes,Budnick-2018-The endoribonuclease YbeY is link,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13945,PHI:9132,UniProt,Q2YK50,GenBank,CAJ12996,,,2308,bab2_0830,chromosome II,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,ABC transporter periplasmic binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29632093,PubMed,10.1128/JB.00105-18,J Bacteriol. 2018 May 24;200(12). pii: e00105-18,caswellc@vt.edu,"Mutants Δbab2_0822, Δbab2_1109 and Δbab2_0700 were less able to survive and replicate in the macrophages than parental strain 2308 at 48 h postinfection, while the other deletion strains displayed wild-type levels of infection.",J A Budnick 2018,2018,10 genes,Budnick-2018-The endoribonuclease YbeY is link,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13946,PHI:9133,UniProt,Q2YPA8,GenBank,CAJ10221,,,2308,bab1_0265,chromosome I,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29632093,PubMed,10.1128/JB.00105-18,J Bacteriol. 2018 May 24;200(12). pii: e00105-18,caswellc@vt.edu,"Mutants Δbab2_0822, Δbab2_1109 and Δbab2_0700 were less able to survive and replicate in the macrophages than parental strain 2308 at 48 h postinfection, while the other deletion strains displayed wild-type levels of infection.",J A Budnick 2018,2018,10 genes,Budnick-2018-The endoribonuclease YbeY is link,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13947,PHI:9134,UniProt,Q2YQ23,GenBank,CAJ11026,,,2308,bab1_1070,chromosome I,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,NADPH dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29632093,PubMed,10.1128/JB.00105-18,J Bacteriol. 2018 May 24;200(12). pii: e00105-18,caswellc@vt.edu,"Mutants Δbab2_0822, Δbab2_1109 and Δbab2_0700 were less able to survive and replicate in the macrophages than parental strain 2308 at 48 h postinfection, while the other deletion strains displayed wild-type levels of infection.",J A Budnick 2018,2018,10 genes,Budnick-2018-The endoribonuclease YbeY is link,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13948,PHI:9135,UniProt,P0CP70,GenBank,AAW46622,,,JEC21,ATG1,chromosome 12,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; blood; liver; spleen; kidney,serine/threonine-protein kinase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29986893,PubMed,10.1128/IAI.00069-18,Infect Immun. 2018 Aug 22;86(9). pii: e00069-18,kronstad@msl.ubc.ca,"The atg1Δ and atg8Δ mutants stimulated an exaggerated host immune response, which, in turn, contributed to disease severity.",H Ding 2018,2018,4 genes,Ding-2018-ATG genes influence the virulence of,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13949,PHI:9136,UniProt,P0CM38,GenBank,AAW45433,,,JEC21,ATG7,chromosome 9,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; blood; liver; spleen; kidney,"ubiquitin-like conjugating enzyme, putative",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29986893,PubMed,10.1128/IAI.00069-18,Infect Immun. 2018 Aug 22;86(9). pii: e00069-18,kronstad@msl.ubc.ca,"The atg1Δ and atg8Δ mutants stimulated an exaggerated host immune response, which, in turn, contributed to disease severity.",H Ding 2018,2018,4 genes,Ding-2018-ATG genes influence the virulence of,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13950,PHI:9137,UniProt,P0CO54,GenBank,AAW41320,,,JEC21,ATG8,chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; blood; liver; spleen; kidney,"microtubule binding protein, putative",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29986893,PubMed,10.1128/IAI.00069-18,Infect Immun. 2018 Aug 22;86(9). pii: e00069-18,kronstad@msl.ubc.ca,"The atg1Δ and atg8Δ mutants stimulated an exaggerated host immune response, which, in turn, contributed to disease severity.",H Ding 2018,2018,4 genes,Ding-2018-ATG genes influence the virulence of,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13951,PHI:9138,UniProt,P0CM40,GenBank,AAW43167,,,JEC21,ATG9,chromosome 4,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; blood; liver; spleen; kidney,"autophagic vacuole formation-related protein, putative",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29986893,PubMed,10.1128/IAI.00069-18,Infect Immun. 2018 Aug 22;86(9). pii: e00069-18,kronstad@msl.ubc.ca,"The atg1Δ and atg8Δ mutants stimulated an exaggerated host immune response, which, in turn, contributed to disease severity.",H Ding 2018,2018,4 genes,Ding-2018-ATG genes influence the virulence of,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13952,PHI:9135,UniProt,P0CP70,GenBank,AAW46622,,,JEC21,ATG1,chromosome 12,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,serine/threonine-protein kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29986893,PubMed,10.1128/IAI.00069-18,Infect Immun. 2018 Aug 22;86(9). pii: e00069-18,kronstad@msl.ubc.ca,Only the atg7Δ mutant showed significantly reduced intracellular replication during a 24-h incubation with the J774.A1 murine macrophage-like cell line.,H Ding 2018,2018,4 genes,Ding-2018-ATG genes influence the virulence of,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13953,PHI:9136,UniProt,P0CM38,GenBank,AAW45433,,,JEC21,ATG7,chromosome 9,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,"ubiquitin-like conjugating enzyme, putative",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29986893,PubMed,10.1128/IAI.00069-18,Infect Immun. 2018 Aug 22;86(9). pii: e00069-18,kronstad@msl.ubc.ca,Only the atg7Δ mutant showed significantly reduced intracellular replication during a 24-h incubation with the J774.A1 murine macrophage-like cell line.,H Ding 2018,2018,4 genes,Ding-2018-ATG genes influence the virulence of,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13954,PHI:9137,UniProt,P0CO54,GenBank,AAW41320,,,JEC21,ATG8,chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,"microtubule binding protein, putative",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29986893,PubMed,10.1128/IAI.00069-18,Infect Immun. 2018 Aug 22;86(9). pii: e00069-18,kronstad@msl.ubc.ca,Only the atg7Δ mutant showed significantly reduced intracellular replication during a 24-h incubation with the J774.A1 murine macrophage-like cell line.,H Ding 2018,2018,4 genes,Ding-2018-ATG genes influence the virulence of,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13955,PHI:9138,UniProt,P0CM40,GenBank,AAW43167,,,JEC21,ATG9,chromosome 4,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,"autophagic vacuole formation-related protein, putative",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29986893,PubMed,10.1128/IAI.00069-18,Infect Immun. 2018 Aug 22;86(9). pii: e00069-18,kronstad@msl.ubc.ca,Only the atg7Δ mutant showed significantly reduced intracellular replication during a 24-h incubation with the J774.A1 murine macrophage-like cell line.,H Ding 2018,2018,4 genes,Ding-2018-ATG genes influence the virulence of,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13956,PHI:9139,UniProt,Q17ZY8,GenBank,CAJ70142,,,630,PrdR,,,,,,,1496,Clostridioides difficile,,JIR8094,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,proline-responsive regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,clindamycin,clindamycin: CHEBI:3745,,,,,gene deletion: full; gene complementation,,,YVS,30882947,PubMed,10.1111/mmi.14245,Mol Microbiol. 2019 Mar 18,linc.sonenshein@tufts.edu,A null mutation in prdR but not in rex increased the severity of C. difficile infection in hamsters.,L Bouillaut 2019,2019,2 genes,Bouillaut-2019-Role of the global regulator Re,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13957,PHI:9140,UniProt,Q18CR5,GenBank,CAJ66992,,,630,Rex,,,,,,,1496,Clostridioides difficile,,JIR8094,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,global redox-sensing regulator,,,,reduced virulence,,,,,,,,,,no,clindamycin,clindamycin: CHEBI:3745,,,,,gene deletion: full; gene complementation,,,YVS,30882947,PubMed,10.1111/mmi.14245,Mol Microbiol. 2019 Mar 18,linc.sonenshein@tufts.edu,A null mutation in prdR but not in rex increased the severity of C. difficile infection in hamsters.,L Bouillaut 2019,2019,2 genes,Bouillaut-2019-Role of the global regulator Re,BATCH_092B,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13958,PHI:9141,UniProt,K9G0Q2,GenBank,EKV14402,,,Pd1,PdSlt2 (PDIP_43770),,,,,,,36651,Penicillium digitatum,1170230,Pd1,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,mitogen-activated protein (MAP) kinase,,,,reduced virulence,,,,,,reduced; aberrant,,,,no,imazalil (IMZ); prochloraz (PCL); philabuster(PHI); thiabendazol(TBZ),imazalil (IMZ): CHEBI:83829; prochloraz (PCL): CHEBI:8434; Philabuster (PHI) thiabendazole (TBZ): CHEBI:45979,,,,,gene deletion: full,,,YVS,29122178,PubMed,10.1016/j.funbio.2017.09.004,Fungal Biol. 2017 Dec;121(12):1063-1074,pasantor@upv.es,"The ΔPdSlt2 mutants were defective in asexual reproduction, showing impairment of sporulation during citrus infection.",M de Ramón-Carbonell 2017,2017,1 gene,de Ramon-Carbon-2017-PdSlt2 Penicillium digita,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13959,PHI:9142,UniProt,V6RQ48,GenBank,CEF85771,,,PH-1,FgAP2alpha (FGSG_09735),chromosome 4,,,FgAP2β (FGSG_00824),UniProt: I1RBB2; GenBank: XP_011316539,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower; spikelet,AP-2 complex subunit alpha,,,,reduced virulence,,no,,,,reduced; aberrant,wild type,reduced; aberrant,reduced,no,calcofluor white (CFW); Congo red (CR); SDS; H2O2; KCl; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31087807,PubMed,10.1111/cmi.13041,Cell Microbiol. 2019 May 14:e13041,lgd@fafu.edu.cn,"Lack of any subunit (FgAP2α , FgAP2β , FgAP2σ and FgAP2mu) of the FgAP-2 complex significantly affected the fungal vegetative growth, conidial morphology and germination.",J Zhang 2019,2019,4 genes,Zhang-2019-FgAP-2 complex is essential for pat,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13960,PHI:9143,UniProt,I1RBB2,GenBank,XP_011316539,,,PH-1; NRRL 31084,FgAP2beta (FGSG_00824),chromosome 1,,,FgAP2α (FGSG_09735); FgAP2mu (FGSG_05093),UniProt: V6RQ48; GenBank: CEF85771; UniProt: Q4ICG5; GenBank: ESU11011,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower; spikelet,AP-2 complex subunit beta,,,,reduced virulence,,no,,,,reduced; aberrant,wild type,reduced; aberrant,reduced,no,calcofluor white (CFW); Congo red (CR); SDS; H2O2; KCl; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31087807,PubMed,10.1111/cmi.13041,Cell Microbiol. 2019 May 14:e13041,lgd@fafu.edu.cn,"Lack of any subunit (FgAP2α , FgAP2β , FgAP2σ and FgAP2mu) of the FgAP-2 complex significantly affected the fungal vegetative growth, conidial morphology and germination.",J Zhang 2019,2019,4 genes,Zhang-2019-FgAP-2 complex is essential for pat,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13961,PHI:9144,UniProt,I1REC8,GenBank,CEF74238,,,PH-1,FgAP2sigma (FGSG_02015),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower; spikelet,carboxylic ester hydrolase,,,,reduced virulence,,no,,,,reduced; aberrant,wild type,reduced; aberrant,reduced,no,calcofluor white (CFW); Congo red (CR); SDS; H2O2; KCl; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31087807,PubMed,10.1111/cmi.13041,Cell Microbiol. 2019 May 14:e13041,lgd@fafu.edu.cn,"Lack of any subunit (FgAP2α , FgAP2β , FgAP2σ and FgAP2mu) of the FgAP-2 complex significantly affected the fungal vegetative growth, conidial morphology and germination.",J Zhang 2019,2019,4 genes,Zhang-2019-FgAP-2 complex is essential for pat,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13962,PHI:9145,UniProt,Q4ICG5,GenBank,ESU11011,,,PH-1; NRRL 31084,FgAP2mu (FGSG_05093),chromosome 3,,,FgAP2β (FGSG_00824),UniProt: I1RBB2; GenBank: XP_011316539,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,flower; spikelet,AP-2 complex subunit sigma,,,,reduced virulence,,no,,,,reduced; aberrant,wild type,reduced; aberrant,reduced,no,calcofluor white (CFW); Congo red (CR); SDS; H2O2; KCl; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31087807,PubMed,10.1111/cmi.13041,Cell Microbiol. 2019 May 14:e13041,lgd@fafu.edu.cn,"Lack of any subunit (FgAP2α , FgAP2β , FgAP2σ and FgAP2mu) of the FgAP-2 complex significantly affected the fungal vegetative growth, conidial morphology and germination.",J Zhang 2019,2019,4 genes,Zhang-2019-FgAP-2 complex is essential for pat,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13963,PHI:9146,UniProt,A0A1D8PQ78,GenBank,AOW30295,,,SC5314,CaCDC50 (orf19.5735),chromosome 6,,,,,,5476,Candida albicans,,RM1000,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,lipid flippase subunit,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,terbinafine; caspofungin; fluconazole; ketoconazole; itraconazole; sodium dodecyl sulfate; ZnSO4; CuSO4; CdCl2; CoCl2; LiCl,terbinafine: CHEBI:9448; caspofungin: CHEBI:474180; fluconazole: CHEBI:46081; ketoconazole: CHEBI:48336; itraconazole: CHEBI:6076; sodium dodecyl sulfate: CHEBI:8984; ZnSO4: CHEBI:35176; CuSO4: CHEBI:23414; CoCl2: CHEBI:35696; CdCl2: CHEBI:35456; LiCl: CHEBI:48607,,,,,gene deletion: full; gene complementation,,,YVS,31004489,PubMed,10.1093/femsyr/foz033,FEMS Yeast Res. 2019 May 1;19(3). pii: foz033,lifengmicro@163.com,"Deletion of CaCDC50 rendered C. albicans cells defective in endocytosis, vacuolar function and the ion stress response.",D Xu 2019,2019,1 gene,Xu-2019-The lipid flippase subunit Cdc50 is re,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13964,PHI:9147,UniProt,B1MGW0,GenBank,CAM60644,,,ATCC 19977,lsr2 (MAB_0545),,,,,,,36809,Mycobacteroides abscessus,,19977-IP,pulmonary infection; cutaneo-mucous infection,rodents,10090,Mus musculus (related: house mouse),J774.2 cell line,,,macrophage,small nucleoid-associated protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31114557,PubMed,10.3389/fmicb.2019.00905,Front Microbiol. 2019 Apr 30;10:905,jean-louis.herrmann@aphp.fr,Lsr2 was required for intracellular survival of M. abscessus S/R forms in both macrophages and amoebae.,V Le Moigne 2019,2019,1 gene,Le Moigne-2019-Lsr2 Is an Important Determinan,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13965,PHI:9147,UniProt,B1MGW0,GenBank,CAM60644,,,ATCC 19977,lsr2 (MAB_0545),,,,,,,36809,Mycobacteroides abscessus,,19977-IP,pulmonary infection; cutaneo-mucous infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),ATCC 30010,,,,small nucleoid-associated protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31114557,PubMed,10.3389/fmicb.2019.00905,Front Microbiol. 2019 Apr 30;10:905,jean-louis.herrmann@aphp.fr,Lsr2 was required for intracellular survival of M. abscessus S/R forms in both macrophages and amoebae.,V Le Moigne 2019,2019,1 gene,Le Moigne-2019-Lsr2 Is an Important Determinan,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13966,PHI:9147,UniProt,B1MGW0,GenBank,CAM60644,,,ATCC 19977,lsr2 (MAB_0545),,,,,,,36809,Mycobacteroides abscessus,,19977-IP,pulmonary infection; cutaneo-mucous infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; liver,small nucleoid-associated protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31114557,PubMed,10.3389/fmicb.2019.00905,Front Microbiol. 2019 Apr 30;10:905,jean-louis.herrmann@aphp.fr,Virulence of the Lsr2 mutants was considerably diminished in cellular models (macrophage and amoeba) as well as in infected animals (mouse and zebrafish).,V Le Moigne 2019,2019,1 gene,Le Moigne-2019-Lsr2 Is an Important Determinan,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13967,PHI:9147,UniProt,B1MGW0,GenBank,CAM60644,,,ATCC 19977,lsr2 (MAB_0545),,,,,,,36809,Mycobacteroides abscessus,,19977-IP,pulmonary infection; cutaneo-mucous infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,small nucleoid-associated protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31114557,PubMed,10.3389/fmicb.2019.00905,Front Microbiol. 2019 Apr 30;10:905,jean-louis.herrmann@aphp.fr,Virulence of the Lsr2 mutants was considerably diminished in cellular models (macrophage and amoeba) as well as in infected animals (mouse and zebrafish).,V Le Moigne 2019,2019,1 gene,Le Moigne-2019-Lsr2 Is an Important Determinan,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13968,PHI:9148,UniProt,Q4WAU2,GenBank,EAL84644,,,Af293,cpsA,chromosome 7,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),Hsd:ICR,,,,putative polysaccharide synthase,,,,reduced virulence,,,,,,reduced,,reduced,,no,nikkomycin Z; SDS; menadione; potassium chloride (KCl); sodium chloride (NaCl); sucrose; sorbitol,nikkomycin Z: CHEBI:623918; SDS: CHEBI:8984; menadione: CHEBI:28869; potassium chloride (KCl): CHEBI:32588; sodium chloride (NaCl): CHEBI:26710; sucrose: CHEBI:17992; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,31026268,PubMed,10.1371/journal.pone.0216092,PLoS One. 2019 Apr 26;14(4):e0216092,amcalvo@niu.edu,"Both deletion and overexpression of cpsA resulted in a reduction in the ability of A. fumigatus to adhere to surfaces, and caused increased sensitivity to oxidative stress.",B Nepal 2019,2019,1 gene,Nepal-2019-Characterization of the putative po,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13969,PHI:9148,UniProt,Q4WAU2,GenBank,EAL84644,,,Af293,cpsA,chromosome 7,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),Hsd:ICR,,,,putative polysaccharide synthase,,,,reduced virulence,,,,,,reduced,,increased; aberrant,,no,nikkomycin Z; SDS; menadione; potassium chloride (KCl); sodium chloride (NaCl); sucrose; sorbitol,nikkomycin Z: CHEBI:623918; SDS: CHEBI:8984; menadione: CHEBI:28869; potassium chloride (KCl): CHEBI:32588; sodium chloride (NaCl): CHEBI:26710; sucrose: CHEBI:17992; sorbitol: CHEBI:30911,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31026268,PubMed,10.1371/journal.pone.0216092,PLoS One. 2019 Apr 26;14(4):e0216092,amcalvo@niu.edu,"Both deletion and overexpression of cpsA resulted in a reduction in the ability of A. fumigatus to adhere to surfaces, and caused increased sensitivity to oxidative stress.",B Nepal 2019,2019,1 gene,Nepal-2019-Characterization of the putative po,BATCH_093A,2019-05-01,MC,,,,,,,,,,,,,
,,Record 13970,PHI:9149,UniProt,A0A384JU41,GenBank,XP_001555733,,,B05.10,Bcbag1 (Bcin10g01250.1/BC1G_05107),chromosome 10,,,Bcbip1; Bcsks2,UniProt: A0A384JT90; GenBank: ATZ53740; UniProt: no data found; GenBank: no data found,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,cytoprotective co-chaperone,,,,reduced virulence,,yes,,,,reduced,,aberrant,reduced,no,NaCl; D-sorbitol; DTT; H2O2; tert-butyl hydroperoxide (TBHP); bortezomib (bort); MG132; calcofluor white (CFW); SDS; iprodione (ipro); fludioxonil (flud); tricyclazole,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; DTT: CHEBI:42170; H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090; bortezomib (Bort): CHEBI:52717; MG132: CHEBI:75142; calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; iprodione (Ipro): CHEBI:28909; fludioxonil (Flud): CHEBI:81763; tricyclazole: CHEBI:81783,,,,,gene deletion: full; gene complementation,,,YVS,31024482,PubMed,10.3389/fmicb.2019.00685,Front Microbiol. 2019 Apr 9;10:685,wangzh@fafu.edu.cn,"BcBAG1 deletion mutants (ΔBcbag1) exhibited decreased conidiation, enhanced melanin accumulation and lost the ability to develop sclerotia.",H Zhang 2019,2019,1 gene,Zhang-2019-Cytoprotective Co-chaperone BcBAG1,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13971,PHI:9149,UniProt,A0A384JU41,GenBank,XP_001555733,,,B05.10,Bcbag1 (Bcin10g01250.1/BC1G_05107),chromosome 10,,,Bcbip1; Bcsks2,UniProt: A0A384JT90; GenBank: ATZ53740; UniProt: no data found; GenBank: no data found,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,cytoprotective co-chaperone,,,,reduced virulence,,yes,,,,reduced,,aberrant,reduced,no,NaCl; D-sorbitol; DTT; H2O2; tert-butyl hydroperoxide (TBHP); bortezomib (bort); MG132; calcofluor white (CFW); SDS; iprodione (ipro); fludioxonil (flud); tricyclazole,NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; DTT: CHEBI:42170; H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090; bortezomib (Bort): CHEBI:52717; MG132: CHEBI:75142; calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; iprodione (Ipro): CHEBI:28909; fludioxonil (Flud): CHEBI:81763; tricyclazole: CHEBI:81783,,,,,gene deletion: full; gene complementation,,,YVS,31024482,PubMed,10.3389/fmicb.2019.00685,Front Microbiol. 2019 Apr 9;10:685,wangzh@fafu.edu.cn,"BcBAG1 deletion mutants (ΔBcbag1) exhibited decreased conidiation, enhanced melanin accumulation and lost the ability to develop sclerotia.",H Zhang 2019,2019,1 gene,Zhang-2019-Cytoprotective Co-chaperone BcBAG1,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13972,PHI:9150,UniProt,P60651,GenBank,AAC75974,,,K-12,speB,,,,,,PHI:9151,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen,agmatinase,,,putrescine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,"The ΔspeB/C mutant showed significantly lower CFU counts in the liver and spleen, but not in the lungs compared with the wild-type.",P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13973,PHI:9151,UniProt,P21169,GenBank,AAC76002,,,K-12,speC,,,,,,PHI:9150,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen,constitutive ornithine decarboxylase,,,putrescine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,"The ΔspeB/C mutant showed significantly lower CFU counts in the liver and spleen, but not in the lungs compared with the wild-type.",P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13974,PHI:9150,UniProt,P60651,GenBank,AAC75974,,,K-12,speB,,,,,,PHI:9151,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,lung,agmatinase,,,putrescine biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,"The ΔspeB/C mutant showed significantly lower CFU counts in the liver and spleen, but not in the lungs compared with the wild-type.",P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13975,PHI:9151,UniProt,P21169,GenBank,AAC76002,,,K-12,speC,,,,,,PHI:9150,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,lung,constitutive ornithine decarboxylase,,,putrescine biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,"The ΔspeB/C mutant showed significantly lower CFU counts in the liver and spleen, but not in the lungs compared with the wild-type.",P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13976,PHI:9152,UniProt,P0A7F6,GenBank,AAC73231,,,K-12,speD,,,,,,PHI:9151,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; lung,S-adenosylmethionine decarboxylase proenzyme,,,spermidine biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,All organs from birds infected with ΔspeD/E showed similar bacterial counts to those observed in the WT infected group.,P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13977,PHI:9153,UniProt,P09158,GenBank,AAC73232,,,K-12,speE,,,,,,PHI:9150,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; lung,polyamine aminopropyltransferase,,,spermidine biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,All organs from birds infected with ΔspeD/E showed similar bacterial counts to those observed in the WT infected group.,P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13978,PHI:9154,UniProt,P0AAF1,GenBank,AAC73786,,,K-12,potE,,,,,,,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,liver; spleen; lung,,,,spermidine biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,"Deletion of polyamine genes, especially the putrescine transport gene potE, resulted in attenuation of the virulence of an APEC strain.",P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13979,PHI:9150,UniProt,P60651,GenBank,AAC75974,,,K-12,speB,,,,,,PHI:9151,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,embryo,agmatinase,,,putrescine biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,No significant difference in the mortality rate of chicken embryos was observed between WT and polyamine biosynthesis and transport mutants.,P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13980,PHI:9151,UniProt,P21169,GenBank,AAC76002,,,K-12,speC,,,,,,PHI:9150,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,embryo,constitutive ornithine decarboxylase,,,putrescine biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,No significant difference in the mortality rate of chicken embryos was observed between WT and polyamine biosynthesis and transport mutants.,P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13981,PHI:9152,UniProt,P0A7F6,GenBank,AAC73231,,,K-12,speD,,,,,,PHI:9153,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,embryo,S-adenosylmethionine decarboxylase proenzyme,,,spermidine biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,No significant difference in the mortality rate of chicken embryos was observed between WT and polyamine biosynthesis and transport mutants.,P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13982,PHI:9153,UniProt,P09158,GenBank,AAC73232,,,K-12,speE,,,,,,PHI:9152,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,embryo,polyamine aminopropyltransferase,,,spermidine biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,No significant difference in the mortality rate of chicken embryos was observed between WT and polyamine biosynthesis and transport mutants.,P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13983,PHI:9154,UniProt,P0AAF1,GenBank,AAC73786,,,K-12,potE,,,,,,,562,Escherichia coli,,APEC serotype O83:H4 ST117,colibacillosis,birds,9031,Gallus gallus (related: chicken),White Leghorn,,,embryo,,,,spermidine biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29519523,PubMed,10.1016/j.vetmic.2018.01.011,Vet Microbiol. 2018 Mar;216:38-44,jeo@sund.ku.dk,No significant difference in the mortality rate of chicken embryos was observed between WT and polyamine biosynthesis and transport mutants.,P R Guerra 2018,2018,5 genes,Guerra-2018-The membrane transporter PotE is r,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13984,PHI:9155,UniProt,I1RE18,GenBank,CEF74091,,,PH-1,FgPep12 (FGSG_01890),chromosome 1,,,FgVam7; FgNeo1,UniProt: A0A098DWK6; GenBank: CEF85729; UniProt: I1RMF9; GenBank: CEF87437,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,t-SNARE protein,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,reduced; aberrant,wild type,reduced; aberrant,,no,CsCl; glyburide; TMB8; DIDS; 9-AC,CsCl: CHEBI:63039; glyburide: CHEBI:5441; TMB8 CAS no.: CAS:57818-92-5; DIDS: CHEBI:36511; 9-anthracenecarboxylic acid (9-AC): CHEBI:34507,,,,,gene mutation; gene complementation,,,YVS,31067272,PubMed,10.1371/journal.ppat.1007754,PLoS Pathog. 2019 May 8;15(5):e1007754,hfzhang@njau.edu.cn,"Deletion of FgPep12 caused defects in vegetative growth, conidiogenesis, deoxynivalenol production and virulence.",B Li 2019,2019,3 genes,"Li-2019-The t-SNARE protein FgPep12, associate",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13985,PHI:9156,UniProt,A0A098DWK6,GenBank,CEF85729,,,PH-1,FgVam7,chromosome 4,,,FgPep12; FgNeo1,UniProt: I1RE18; GenBank: CEF74091; UniProt: I1RMF9; GenBank: CEF87437,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,SNARE protein,,,,reduced virulence,,,,,,,reduced,,,no,CsCl; glyburide; TMB8; DIDS; 9-AC,CsCl: CHEBI:63039; glyburide: CHEBI:5441; TMB8 CAS no.: CAS:57818-92-5; DIDS: CHEBI:36511; 9-anthracenecarboxylic acid (9-AC): CHEBI:34507,,,,,gene mutation,,,YVS,31067272,PubMed,10.1371/journal.ppat.1007754,PLoS Pathog. 2019 May 8;15(5):e1007754,hfzhang@njau.edu.cn,Both FgPep12 and FgVam7 were essential for ascospore discharge through interaction with and trafficking of the Ca2+ ATPase FgNeo1 between the Golgi and endosomal/vacuolar system.,B Li 2019,2019,3 genes,"Li-2019-The t-SNARE protein FgPep12, associate",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13986,PHI:9157,UniProt,I1RMF9,GenBank,CEF87437,,,PH-1,FgNeo1 (FGSG_05149),chromosome 3,,,FgPep12; FgVam7,UniProt: I1RE18; GenBank: CEF74091; UniProt: A0A098DWK6; GenBank: CEF85729,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,phospholipid-transporting ATPase,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,,,,,,,gene mutation,,,YVS,31067272,PubMed,10.1371/journal.ppat.1007754,PLoS Pathog. 2019 May 8;15(5):e1007754,hfzhang@njau.edu.cn,Both FgPep12 and FgVam7 were essential for ascospore discharge through interaction with and trafficking of the Ca2+ ATPase FgNeo1 between the Golgi and endosomal/vacuolar system.,B Li 2019,2019,3 genes,"Li-2019-The t-SNARE protein FgPep12, associate",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13987,PHI:9158,,no data found,GenBank,AGS64743,,,S06004,bcsA,,,,,,,28901,Salmonella enterica,605,serovar Pullorum strain S6702,pullorum disease,birds,9031,Gallus gallus (related: chicken),,,,spleen,cellulose synthase catalytic subunit,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28470089,PubMed,10.1080/03079457.2017.1324198,Avian Pathol. 2017 Oct;46(5):541-547,pengdx@yzu.edu.cn,"ΔCsgA showed decreased production of curli fimbriae, while ΔbcsA had reduced cellulose production and both mutants had a reduced ability to form biofilms.",M El Hag 2017,2017,2 genes,El Hag-2017-Contribution of the csgA and bcsA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13988,PHI:9158,,no data found,GenBank,AGS64743,,,S06004,bcsA,,,,,,,28901,Salmonella enterica,605,serovar Pullorum strain S6702,pullorum disease,birds,9031,Gallus gallus (related: chicken),,,,liver,cellulose synthase catalytic subunit,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28470089,PubMed,10.1080/03079457.2017.1324198,Avian Pathol. 2017 Oct;46(5):541-547,pengdx@yzu.edu.cn,"ΔCsgA showed decreased production of curli fimbriae, while ΔbcsA had reduced cellulose production and both mutants had a reduced ability to form biofilms.",M El Hag 2017,2017,2 genes,El Hag-2017-Contribution of the csgA and bcsA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13989,PHI:9159,,no data found,GenBank,AGS65306,,,S06004,csgA,,,,,,,28901,Salmonella enterica,605,serovar Pullorum strain S6702,pullorum disease,birds,9031,Gallus gallus (related: chicken),,,,spleen,major curlin subunit,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28470089,PubMed,10.1080/03079457.2017.1324198,Avian Pathol. 2017 Oct;46(5):541-547,pengdx@yzu.edu.cn,"ΔCsgA showed decreased production of curli fimbriae, while ΔbcsA had reduced cellulose production and both mutants had a reduced ability to form biofilms.",M El Hag 2017,2017,2 genes,El Hag-2017-Contribution of the csgA and bcsA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13990,PHI:9159,,no data found,GenBank,AGS65306,,,S06004,csgA,,,,,,,28901,Salmonella enterica,605,serovar Pullorum strain S6702,pullorum disease,birds,9031,Gallus gallus (related: chicken),,,,liver,major curlin subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28470089,PubMed,10.1080/03079457.2017.1324198,Avian Pathol. 2017 Oct;46(5):541-547,pengdx@yzu.edu.cn,"ΔCsgA showed decreased production of curli fimbriae, while ΔbcsA had reduced cellulose production and both mutants had a reduced ability to form biofilms.",M El Hag 2017,2017,2 genes,El Hag-2017-Contribution of the csgA and bcsA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13991,PHI:9158,,no data found,GenBank,AGS64743,,,S06004,bcsA,,,,,,,28901,Salmonella enterica,605,serovar Pullorum strain S6702,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,cellulose synthase catalytic subunit,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28470089,PubMed,10.1080/03079457.2017.1324198,Avian Pathol. 2017 Oct;46(5):541-547,pengdx@yzu.edu.cn,ΔBcsA exhibited increased proliferation in HD11 cells.,M El Hag 2017,2017,2 genes,El Hag-2017-Contribution of the csgA and bcsA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13992,PHI:9159,,no data found,GenBank,AGS65306,,,S06004,csgA,,,,,,,28901,Salmonella enterica,605,serovar Pullorum strain S6702,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,major curlin subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28470089,PubMed,10.1080/03079457.2017.1324198,Avian Pathol. 2017 Oct;46(5):541-547,pengdx@yzu.edu.cn,ΔCsgA exhibited decreased intracellular proliferation in HD11 macrophages.,M El Hag 2017,2017,2 genes,El Hag-2017-Contribution of the csgA and bcsA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13993,PHI:9158,,no data found,GenBank,AGS64743,,,S06004,bcsA,,,,,,,28901,Salmonella enterica,605,serovar Pullorum strain S6702,pullorum disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,cellulose synthase catalytic subunit,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28470089,PubMed,10.1080/03079457.2017.1324198,Avian Pathol. 2017 Oct;46(5):541-547,pengdx@yzu.edu.cn,"ΔCsgA was reduced in adhesion and invasion to HeLa cells, as compared with the WT and ΔbcsA strains.",M El Hag 2017,2017,2 genes,El Hag-2017-Contribution of the csgA and bcsA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13994,PHI:9159,,no data found,GenBank,AGS65306,,,S06004,csgA,,,,,,,28901,Salmonella enterica,605,serovar Pullorum strain S6702,pullorum disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,major curlin subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28470089,PubMed,10.1080/03079457.2017.1324198,Avian Pathol. 2017 Oct;46(5):541-547,pengdx@yzu.edu.cn,"ΔCsgA was reduced in adhesion and invasion to HeLa cells, as compared with the WT and ΔbcsA strains.",M El Hag 2017,2017,2 genes,El Hag-2017-Contribution of the csgA and bcsA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13995,PHI:9160,UniProt,Q8ZKC5,GenBank,AAL23144,,,LT2,VarN,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,putative MerR family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29751061,PubMed,10.1016/j.resmic.2018.03.003,Res Microbiol. 2018 May - Jun;169(4-5):214-221,jianglingyan@nankai.edu.cn,"Deletion of varN decreased the transcription of Salmonella pathogenicity island-2 (SPI-2) genes, which were required for S. Typhimurium growth in macrophages.",X Jiang 2018,2018,1 gene,Jiang-2018-The transcriptional regulator VarN,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13996,PHI:9160,UniProt,Q8ZKC5,GenBank,AAL23144,,,LT2,VarN,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative MerR family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29751061,PubMed,10.1016/j.resmic.2018.03.003,Res Microbiol. 2018 May - Jun;169(4-5):214-221,jianglingyan@nankai.edu.cn,"VarN contributed to S. Typhimurium growth in macrophages, but was not involved in intestinal invasion.",X Jiang 2018,2018,1 gene,Jiang-2018-The transcriptional regulator VarN,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13997,PHI:9160,UniProt,Q8ZKC5,GenBank,AAL23144,,,LT2,VarN,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),Caco-2 cell line,,,CACO-2 cell,putative MerR family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,29751061,PubMed,10.1016/j.resmic.2018.03.003,Res Microbiol. 2018 May - Jun;169(4-5):214-221,jianglingyan@nankai.edu.cn,"VarN contributed to S. Typhimurium growth in macrophages, but was not involved in intestinal invasion.",X Jiang 2018,2018,1 gene,Jiang-2018-The transcriptional regulator VarN,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13998,PHI:9161,UniProt,Q8Z447,GenBank,AAO70421,,,Ty2,RelA,,,,,,PHI:9162,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,FeCl3; desferrioxamine,FeCl3: CHEBI:30808; desferrioxamine: CHEBI:4356,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Absence of the Vi-polysaccharide capsule rendered the mutant strain highly susceptible to complement-mediated lysis.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 13999,PHI:9162,UniProt,Q8Z2I0,GenBank,AAO71259,,,Ty2,SpoT,,,,,,PHI:9161,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,"bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase",,,,reduced virulence,,,,,,,,reduced,,no,FeCl3; desferrioxamine,FeCl3: CHEBI:30808; desferrioxamine: CHEBI:4356,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Absence of the Vi-polysaccharide capsule rendered the mutant strain highly susceptible to complement-mediated lysis.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14000,PHI:9161,UniProt,Q8Z447,GenBank,AAO70421,,,Ty2,RelA,,,,,,PHI:9162,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14001,PHI:9162,UniProt,Q8Z2I0,GenBank,AAO71259,,,Ty2,SpoT,,,,,,PHI:9161,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,"bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14002,PHI:9161,UniProt,Q8Z447,GenBank,AAO70421,,,Ty2,RelA,,,,,,PHI:9162,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colorectal adenocarcinoma cell line,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14003,PHI:9162,UniProt,Q8Z2I0,GenBank,AAO71259,,,Ty2,SpoT,,,,,,PHI:9161,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colorectal adenocarcinoma cell line,"bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14004,PHI:9161,UniProt,Q8Z447,GenBank,AAO70421,,,Ty2,RelA,,,,,,PHI:9162,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),Caco-2 cell line,,,CACO-2 cell,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14005,PHI:9162,UniProt,Q8Z2I0,GenBank,AAO71259,,,Ty2,SpoT,,,,,,PHI:9161,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),Caco-2 cell line,,,CACO-2 cell,"bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14006,PHI:9161,UniProt,Q8Z447,GenBank,AAO70421,,,Ty2,RelA,,,,,,PHI:9162,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14007,PHI:9162,UniProt,Q8Z2I0,GenBank,AAO71259,,,Ty2,SpoT,,,,,,PHI:9161,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,"bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14008,PHI:9161,UniProt,Q8Z447,GenBank,AAO70421,,,Ty2,RelA,,,,,,PHI:9162,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colorectal adenocarcinoma cell line,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14009,PHI:9162,UniProt,Q8Z2I0,GenBank,AAO71259,,,Ty2,SpoT,,,,,,PHI:9161,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colorectal adenocarcinoma cell line,"bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14010,PHI:9161,UniProt,Q8Z447,GenBank,AAO70421,,,Ty2,RelA,,,,,,PHI:9162,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),Caco-2 cell line,,,CACO-2 cell,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14011,PHI:9162,UniProt,Q8Z2I0,GenBank,AAO71259,,,Ty2,SpoT,,,,,,PHI:9161,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),Caco-2 cell line,,,CACO-2 cell,"bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31013389,PubMed,10.1111/cmi.13034,Cell Microbiol. 2019 Apr 23:e13034,santasabujdas@yahoo.com,Ty2ΔRelAΔSpoT had markedly elongated morphology with incomplete septa formation and demonstrated severely attenuated motility and chemotaxis due to the loss of flagella.,S Dasgupta 2019,2019,2 genes,Dasgupta-2019-Small alarmones (p)ppGpp regulat,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14012,PHI:9163,UniProt,A0A063C0A1,GenBank,KDB14758,,,UV-8b,UvBI-1,,,,,,,1159556,Ustilaginoidea virens,,JZ11-28,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,seed,transmembrane BAX inhibitor motif-containing protein,,,,loss of pathogenicity,,,,,,increased,,increased,,no,NaCl; sorbitol; H2O2; sodium dodecyl sulfate (SDS); calcofluor white (CFW); Congo red,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,30993412,PubMed,10.1007/s00294-019-00970-2,Curr Genet. 2019 Apr 11,wxyin@mail.hzau.edu.cn,"The Uvbi-1 mutants exhibited higher sensitivity to osmotic and salt stress, hydrogen peroxide stress, and cell wall or membrane stress than the wild-type strain.",S Xie 2019,2019,1 gene,"Xie-2019-The Bax inhibitor UvBI-1, a negative",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14013,PHI:9164,UniProt,Q7MVN8,GenBank,AAQ66132,,,W83,PG_RS04465 (PG1010),,,,,,,837,Porphyromonas gingivalis,242619,W83,periodontitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"ABC transporter, ATP-binding protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31081181,PubMed,10.1002/jcb.28887,J Cell Biochem. 2019 May 12,zhaochuanjiang17@sina.com,"Knockdown of PG_RS07320, but not PG_RS04465, caused decreased endotoxin level in the bacteria.",L Gao 2019,2019,2 genes,Gao-2019-Research on the roles of genes coding,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14014,PHI:9165,UniProt,Q7MU82,GenBank,AAQ66684,,,W83,PG_RS07320 (PG1665),,,,,,,837,Porphyromonas gingivalis,242619,W83,periodontitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"ABC transporter, permease protein, putative",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31081181,PubMed,10.1002/jcb.28887,J Cell Biochem. 2019 May 12,zhaochuanjiang17@sina.com,"Knockdown of PG_RS07320, but not PG_RS04465, caused decreased endotoxin level in the bacteria.",L Gao 2019,2019,2 genes,Gao-2019-Research on the roles of genes coding,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14015,PHI:9164,UniProt,Q7MVN8,GenBank,AAQ66132,,,W83,PG_RS04465 (PG1010),,,,,,,837,Porphyromonas gingivalis,242619,W83,periodontitis,primates,9606,Homo sapiens (related: human),,,,gingival epithelium,"ABC transporter, ATP-binding protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31081181,PubMed,10.1002/jcb.28887,J Cell Biochem. 2019 May 12,zhaochuanjiang17@sina.com,"Both mutant strains showed decreased Arg- and Lys-gingipains activities, with significantly reduced adhesion and invasion capabilities.",L Gao 2019,2019,2 genes,Gao-2019-Research on the roles of genes coding,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14016,PHI:9165,UniProt,Q7MU82,GenBank,AAQ66684,,,W83,PG_RS07320 (PG1665),,,,,,,837,Porphyromonas gingivalis,242619,W83,periodontitis,primates,9606,Homo sapiens (related: human),,,,gingival epithelium,"ABC transporter, permease protein, putative",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31081181,PubMed,10.1002/jcb.28887,J Cell Biochem. 2019 May 12,zhaochuanjiang17@sina.com,"Both mutant strains showed decreased Arg- and Lys-gingipains activities, with significantly reduced adhesion and invasion capabilities.",L Gao 2019,2019,2 genes,Gao-2019-Research on the roles of genes coding,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14017,PHI:9166,UniProt,A0A0H2X986,GenBank,AAY49876,,,8004,XC_2827,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,transcriptional regulator marR family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31090173,PubMed,10.1111/mpp.12818,Mol Plant Pathol. 2019 May 14,jltang@gxu.edu.cn,Flp influenced previously uncharacterized virulence factors independently of HrpX regulation in Xcc.,M Leng 2019,2019,7 genes,"Leng-2019-Flp, a Fis-like protein, contributes",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14018,PHI:9167,UniProt,A0A0H2XA38,GenBank,AAY50174,,,8004,XC_3129,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,inner membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31090173,PubMed,10.1111/mpp.12818,Mol Plant Pathol. 2019 May 14,jltang@gxu.edu.cn,Flp influenced previously uncharacterized virulence factors independently of HrpX regulation in Xcc.,M Leng 2019,2019,7 genes,"Leng-2019-Flp, a Fis-like protein, contributes",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14019,PHI:9168,UniProt,A0A0H2XBB0,GenBank,AAY50734,,,8004,XC_3694,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31090173,PubMed,10.1111/mpp.12818,Mol Plant Pathol. 2019 May 14,jltang@gxu.edu.cn,Flp influenced previously uncharacterized virulence factors independently of HrpX regulation in Xcc.,M Leng 2019,2019,7 genes,"Leng-2019-Flp, a Fis-like protein, contributes",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14020,PHI:9169,UniProt,A0A0H2X5M1,GenBank,AAY48342,,,8004,XC_1273,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,voltage-gated potassium channel,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31090173,PubMed,10.1111/mpp.12818,Mol Plant Pathol. 2019 May 14,jltang@gxu.edu.cn,Flp influenced previously uncharacterized virulence factors independently of HrpX regulation in Xcc.,M Leng 2019,2019,7 genes,"Leng-2019-Flp, a Fis-like protein, contributes",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14021,PHI:9170,UniProt,A0A0H2X8T1,GenBank,AAY49708,,,8004,XC_2659,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,quinoprotein glucose dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31090173,PubMed,10.1111/mpp.12818,Mol Plant Pathol. 2019 May 14,jltang@gxu.edu.cn,Flp influenced previously uncharacterized virulence factors independently of HrpX regulation in Xcc.,M Leng 2019,2019,7 genes,"Leng-2019-Flp, a Fis-like protein, contributes",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14022,PHI:9171,UniProt,A0A0H2XC47,GenBank,AAY51041,,,8004,XC_4002,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31090173,PubMed,10.1111/mpp.12818,Mol Plant Pathol. 2019 May 14,jltang@gxu.edu.cn,Flp influenced previously uncharacterized virulence factors independently of HrpX regulation in Xcc.,M Leng 2019,2019,7 genes,"Leng-2019-Flp, a Fis-like protein, contributes",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14023,PHI:9172,UniProt,A0A0H2X4X9,GenBank,AAY47601,,,8004,XC_0520 (flp),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,Fis-like DNA-binding protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); H2O2; NaCl; phenol; CdCl2; CuSO4,sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:26710; phenol: CHEBI:15882; CdCl2: CHEBI:35456; CuSO4: CHEBI:23414,,,,,gene deletion: full; gene complementation,,,YVS,31090173,PubMed,10.1111/mpp.12818,Mol Plant Pathol. 2019 May 14,jltang@gxu.edu.cn,The constitutive expression of hrpX in the flp mutant restored the HR phenotype but not full virulence.,M Leng 2019,2019,7 genes,"Leng-2019-Flp, a Fis-like protein, contributes",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14024,PHI:9172,UniProt,A0A0H2X4X9,GenBank,AAY47601,,,8004,XC_0520 (flp),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,Fis-like DNA-binding protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); H2O2; NaCl; phenol; CdCl2; CuSO4,sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:26710; phenol: CHEBI:15882; CdCl2: CHEBI:35456; CuSO4: CHEBI:23414,,,,,gene deletion: full; gene complementation,,,YVS,31090173,PubMed,10.1111/mpp.12818,Mol Plant Pathol. 2019 May 14,jltang@gxu.edu.cn,The constitutive expression of hrpX in the flp mutant restored the HR phenotype but not full virulence.,M Leng 2019,2019,7 genes,"Leng-2019-Flp, a Fis-like protein, contributes",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14025,PHI:9173,UniProt,A0A384JJ77,GenBank,XP_024549063,,,B05.10,BcHBF1 (BCIN_06g00240),chromosome 6,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,B. cinerea hyphal branching-related factor 1,,,,reduced virulence,,yes,yes,,,aberrant,,wild type,wild type,no,NaCl; KCl; H2O2; sodium dodecyl sulfate (SDS); Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31008573,PubMed,10.1111/mpp.12788,Mol Plant Pathol. 2019 May;20(5):731-747,qmqin@jlu.edu.cn,"Deletion of BcHBF1 in B. cinerea did not impair radial growth of mycelia, conidiation, conidial germination, osmotic- and oxidative-stress adaptation, as well as cell wall integrity of the mutant strains.",Y Liu 2019,2019,1 gene,Liu-2019-A novel Botrytis cinerea-specific gen,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14026,PHI:9174,UniProt,I1RD66,GenBank,CEF73702,,,PH-1,FgTfmI (FGSG_01555),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,b-ZIP transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,phenamacril,phenamacril: CAS:3336-69-4,,,,,gene deletion: full; gene complementation,,,YVS,31025482,PubMed,10.1002/ps.5454,Pest Manag Sci. 2019 Apr 26,chenyun0927@zju.edu.cn,The deletion mutant of FgTFMI (ΔFgTfmI) displayed a slight growth defect and showed hypersensitivity to phenamacril.,N Liu 2019,2019,1 gene,Liu-2019-The b-ZIP transcription factor FgTfmI,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14027,PHI:9174,UniProt,I1RD66,GenBank,CEF73702,,,PH-1,FgTfmI (FGSG_01555),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,b-ZIP transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,phenamacril,phenamacril: CAS:3336-69-4,,,,,gene deletion: full; gene complementation,,,YVS,31025482,PubMed,10.1002/ps.5454,Pest Manag Sci. 2019 Apr 26,chenyun0927@zju.edu.cn,The deletion mutant of FgTFMI (ΔFgTfmI) displayed a slight growth defect and showed hypersensitivity to phenamacril.,N Liu 2019,2019,1 gene,Liu-2019-The b-ZIP transcription factor FgTfmI,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14028,PHI:9175,UniProt,P74856,GenBank,CAA70536,,,LT2,ssaV,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,phenylarsine oxide (PAO); DPI,phenylarsine oxide (PAO): CHEBI:75253; diphenyleneiodonium chloride (dpi): CHEBI:77967,,,,,gene mutation,,,YVS,31009521,PubMed,10.1371/journal.ppat.1007741,PLoS Pathog. 2019 Apr 22;15(4):e1007741,Michael.Hensel@biologie.uni-osnabrueck.de,"STM infection of macrophages induced ROS generation, and ROS affected intracellular survival and replication of STM ΔsseF and ΔssaV more severely than STM WT.",J Noster 2019,2019,2 genes,Noster-2019-Proteomics of intracellular Salmon,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14029,PHI:9176,UniProt,H9L407,GenBank,AAL20328,,,LT2,sseF,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,SPI-2 effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,phenylarsine oxide (PAO); DPI,phenylarsine oxide (PAO): CHEBI:75253; diphenyleneiodonium chloride (dpi): CHEBI:77967,,,,,gene mutation,,,YVS,31009521,PubMed,10.1371/journal.ppat.1007741,PLoS Pathog. 2019 Apr 22;15(4):e1007741,Michael.Hensel@biologie.uni-osnabrueck.de,"STM infection of macrophages induced ROS generation, and ROS affected intracellular survival and replication of STM ΔsseF and ΔssaV more severely than STM WT.",J Noster 2019,2019,2 genes,Noster-2019-Proteomics of intracellular Salmon,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14030,PHI:9177,UniProt,A0A0F6B8Q0,GenBank,ACY90898,,,14028S,HilE (STM14_4514),,,,HilD,UniProt: P0CL08; GenBank: AAL21755,PHI:9178,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; spleen,putative inner membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29378886,PubMed,10.1128/JB.00750-17,J Bacteriol. 2018 Mar 26;200(8),slauch@illinois.edu,Deletion of hilE was capable of partially rescuing the invasion deficit conferred by ΔfliZ.,J R Grenz 2018,2018,2 genes,Grenz-2018-HilE Regulates HilD by Blocking DNA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14031,PHI:9178,UniProt,P0A210,GenBank,BAA36398,,,KK1004,FliZ,,,,,,PHI:9177,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; spleen,flagellar protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29378886,PubMed,10.1128/JB.00750-17,J Bacteriol. 2018 Mar 26;200(8),slauch@illinois.edu,Deletion of hilE was capable of partially rescuing the invasion deficit conferred by ΔfliZ.,J R Grenz 2018,2018,2 genes,Grenz-2018-HilE Regulates HilD by Blocking DNA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14032,PHI:9177,UniProt,A0A0F6B8Q0,GenBank,ACY90898,,,14028S,HilE (STM14_4514),,,,HilD,UniProt: P0CL08; GenBank: AAL21755,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; spleen,putative inner membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29378886,PubMed,10.1128/JB.00750-17,J Bacteriol. 2018 Mar 26;200(8),slauch@illinois.edu,Deletion of hilE was capable of partially rescuing the invasion deficit conferred by ΔfliZ.,J R Grenz 2018,2018,2 genes,Grenz-2018-HilE Regulates HilD by Blocking DNA,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14033,PHI:9179,UniProt,G4N6V5,GenBank,EHA50719,,,70-15,MoAP1 (MGG_12814),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Taipei309,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31024598,PubMed,10.3389/fpls.2019.00433,Front Plant Sci. 2019 Apr 9;10:433,j316wenmingwang@sicau.edu.cn,"Silencing of M. oryzae MoAP1 resulted in inhibited fungal growth, abnormal spores and decreased pathogenicity.",X Y Guo 2019,2019,4 genes,Guo-2019-Host-Induced Gene Silencing of MoAP1,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14034,PHI:9180,UniProt,G4MXJ4,GenBank,EHA54325,,,70-15,MoSSADH (MGG_01230),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Taipei309,,,leaf,succinate-semialdehyde dehydrogenase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31024598,PubMed,10.3389/fpls.2019.00433,Front Plant Sci. 2019 Apr 9;10:433,j316wenmingwang@sicau.edu.cn,"The asiRNAs targeting three other genes (i.e., MoSSADH, MoACT, and MoSOM1) had no effect on fungal growth.",X Y Guo 2019,2019,4 genes,Guo-2019-Host-Induced Gene Silencing of MoAP1,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14035,PHI:9181,,no data found,GenBank,MGG_15157,,,,MoACT (MGG_15157),,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Taipei309,,,leaf,acetyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31024598,PubMed,10.3389/fpls.2019.00433,Front Plant Sci. 2019 Apr 9;10:433,j316wenmingwang@sicau.edu.cn,"The asiRNAs targeting three other genes (i.e., MoSSADH, MoACT, and MoSOM1) had no effect on fungal growth.",X Y Guo 2019,2019,4 genes,Guo-2019-Host-Induced Gene Silencing of MoAP1,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14036,PHI:9182,UniProt,G4MR98,GenBank,EHA58223,,,70-15,MoSOM1 (MGG_04708),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Taipei309,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31024598,PubMed,10.3389/fpls.2019.00433,Front Plant Sci. 2019 Apr 9;10:433,j316wenmingwang@sicau.edu.cn,"The asiRNAs targeting three other genes (i.e., MoSSADH, MoACT, and MoSOM1) had no effect on fungal growth.",X Y Guo 2019,2019,4 genes,Guo-2019-Host-Induced Gene Silencing of MoAP1,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14037,PHI:9183,UniProt,B0XQR1,GenBank,EDP56375,,,A1163,ssdA (AFUB_010850),,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,cell wall biogenesis protein phosphatase,,,,reduced virulence,,,,,,,,reduced,reduced,no,Congo red; calcofluor white; caspofungin,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; caspofungin: CHEBI:474180,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31068436,PubMed,10.1128/mSphere.00244-19,mSphere. 2019 May 8;4(3),Robert.A.Cramer.Jr@dartmouth.edu,"Increased SsdA levels attenuated A. fumigatus virulence, likely through fungal fitness defects, while loss of SsdA altered the host immune response and modestly increased fungal virulence in vivo.",A Thammahong 2019,2019,1 gene,Thammahong-2019-An Ssd1 Homolog Impacts Trehal,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14038,PHI:9183,UniProt,B0XQR1,GenBank,EDP56375,,,A1163,ssdA (AFUB_010850),,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,cell wall biogenesis protein phosphatase,,,,increased virulence (hypervirulence),,,,,,,,reduced,increased,no,Congo red; calcofluor white; caspofungin,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31068436,PubMed,10.1128/mSphere.00244-19,mSphere. 2019 May 8;4(3),Robert.A.Cramer.Jr@dartmouth.edu,"Increased SsdA levels attenuated A. fumigatus virulence, likely through fungal fitness defects, while loss of SsdA altered the host immune response and modestly increased fungal virulence in vivo.",A Thammahong 2019,2019,1 gene,Thammahong-2019-An Ssd1 Homolog Impacts Trehal,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14039,PHI:9184,UniProt,A0A0H3LK50,GenBank,CAE32125,,,RB50,bscN,,,,,,,518,Bordetella bronchiseptica,,S798,infectious bronchitis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,trachea,putative ATP synthase in type III secretion,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31019000,PubMed,10.1128/mSphere.00093-19,mSphere. 2019 Apr 24;4(2),horiguti@biken.osaka-u.ac.jp,"Rats infected with S798 (ΔbscN), which is deficient in type III secretion, tended to exhibit more frequent coughing during the period of counting; however, the difference was statistically nonsignificant.",K Nakamura 2019,2019,7 genes,"Nakamura-2019-BspR_BtrA, an Anti-sigma Factor",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14040,PHI:9185,UniProt,A0A0H3LK84,GenBank,CAE32136,,,RB50,BB_RS08175 (BspR/BtrA/(BB1639),,single base (C) deletion,,,,,518,Bordetella bronchiseptica,,S798,infectious bronchitis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,trachea,"anti-σ factor, type III secreted protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31019000,PubMed,10.1128/mSphere.00093-19,mSphere. 2019 Apr 24;4(2),horiguti@biken.osaka-u.ac.jp,"Infection with bspR (btrA)-deficient strains caused significantly less frequent coughing than the wild type; however, intranasal inoculation of the lysates from a bspR (btrA)-deficient strain caused coughing similarly to the wild type, suggesting that BspR/BtrA regulated the production of the cough factor(s) only when the bacteria colonize host bodies.",K Nakamura 2019,2019,7 genes,"Nakamura-2019-BspR_BtrA, an Anti-sigma Factor",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14041,PHI:9186,UniProt,Q7WDU8,GenBank,CAE35253,,,RB50,ptxA,,"RB50 derivative, ptxA-ptlH::Cmr",,,,PHI:9187,518,Bordetella bronchiseptica,257310,RB50,infectious bronchitis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,trachea,pertussis toxin subunit 1 precursor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31019000,PubMed,10.1128/mSphere.00093-19,mSphere. 2019 Apr 24;4(2),horiguti@biken.osaka-u.ac.jp,"RΔptxptl also caused coughing, demonstrating that pertussis toxin did not play a role in cough production even if produced by B. bronchiseptica.",K Nakamura 2019,2019,7 genes,"Nakamura-2019-BspR_BtrA, an Anti-sigma Factor",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14042,PHI:9187,UniProt,Q7WDT5,GenBank,CAE35266,,,RB50,ptlH,,"RB50 derivative, ptxA-ptlH::Cmr",,,,PHI:9186,518,Bordetella bronchiseptica,257310,RB50,infectious bronchitis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,trachea,putative bacterial secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31019000,PubMed,10.1128/mSphere.00093-19,mSphere. 2019 Apr 24;4(2),horiguti@biken.osaka-u.ac.jp,"RΔptxptl also caused coughing, demonstrating that pertussis toxin did not play a role in cough production even if produced by B. bronchiseptica.",K Nakamura 2019,2019,7 genes,"Nakamura-2019-BspR_BtrA, an Anti-sigma Factor",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14043,PHI:9185,UniProt,A0A0H3LK84,GenBank,CAE32136,,,RB50,BB_RS08175 (BspR/BtrA/(BB1639),,single base (C) deletion,,,,,518,Bordetella bronchiseptica,257310,RB50,infectious bronchitis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,trachea,"anti-σ factor, type III secreted protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31019000,PubMed,10.1128/mSphere.00093-19,mSphere. 2019 Apr 24;4(2),horiguti@biken.osaka-u.ac.jp,"Infection with bspR (btrA)-deficient strains caused significantly less frequent coughing than the wild type; however, intranasal inoculation of the lysates from a bspR (btrA)-deficient strain caused coughing similarly to the wild type, suggesting that BspR/BtrA regulated the production of the cough factor(s) only when the bacteria colonize host bodies.",K Nakamura 2019,2019,7 genes,"Nakamura-2019-BspR_BtrA, an Anti-sigma Factor",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14044,PHI:9188,UniProt,A0A0H3LPR7,GenBank,CAE32015,,,RB50,BB_RS07570 (BB1518),,single base (G) insertion,,,,,518,Bordetella bronchiseptica,257310,RB50,infectious bronchitis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,trachea,putative hydrolase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31019000,PubMed,10.1128/mSphere.00093-19,mSphere. 2019 Apr 24;4(2),horiguti@biken.osaka-u.ac.jp,Mutant strains with deletion in BB_RS07570 (RΔ07570) or BB_RS14645 (RΔ14645) colonized rat tracheas and produced cough to an extent comparable to the wild type.,K Nakamura 2019,2019,7 genes,"Nakamura-2019-BspR_BtrA, an Anti-sigma Factor",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14045,PHI:9189,UniProt,A0A0H3LPZ5,GenBank,CAE33410,,,RB50,BB_RS14645 (BB2918),,nonsynonymous base substitution (C to A),,,,,518,Bordetella bronchiseptica,257310,RB50,infectious bronchitis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,trachea,putative type I polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31019000,PubMed,10.1128/mSphere.00093-19,mSphere. 2019 Apr 24;4(2),horiguti@biken.osaka-u.ac.jp,Mutant strains with deletion in BB_RS07570 (RΔ07570) or BB_RS14645 (RΔ14645) colonized rat tracheas and produced cough to an extent comparable to the wild type.,K Nakamura 2019,2019,7 genes,"Nakamura-2019-BspR_BtrA, an Anti-sigma Factor",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14046,PHI:9190,UniProt,Q7VWI6,GenBank,CAE42509,,,Tohama I,BspR/BtrA (BP2233),,,,,,,520,Bordetella pertussis,257313,Tohama I,pertussis,rodents,10117,Rattus rattus (related: black rat),Wistar,,,trachea,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31019000,PubMed,10.1128/mSphere.00093-19,mSphere. 2019 Apr 24;4(2),horiguti@biken.osaka-u.ac.jp,BspR (btrA) (BP2233)-deficient mutant (TΔbspR) of B. pertussis Tohama I induced rat coughing.,K Nakamura 2019,2019,7 genes,"Nakamura-2019-BspR_BtrA, an Anti-sigma Factor",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14047,PHI:9191,UniProt,W7MG06,GenBank,EWG46455,,,7600,Fvset2 (FVEG_06937),chromosome 7,,,,,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),cv. B73,,,kernel,histone-lysine N-methyltransferase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28778753,PubMed,10.1016/j.fgb.2017.07.007,Fungal Genet Biol. 2017 Oct;107:24-30,hjwu@njau.edu.cn,"The FvSET2 deletion mutant (ΔFvSet2) showed significant defects in vegetative growth, FB1 biosynthesis, pigmentation and fungal virulence.",Q Gu 2017,2017,1 gene,"Gu-2017-FvSet2 regulates fungal growth, pathog",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14048,PHI:9192,UniProt,A0A0D2X8F5,GenBank,KNA93804,,,4287,Foatg22,chromosome 1,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,tuber; leaf,ubiquitin-like protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31086099,PubMed,10.3390/genes10050365,Genes (Basel). 2019 May 13;10(5),haseeb78692@yahoo.com,"ΔFoatg22 strains exhibited a decrease in hyphal development and conidiation, and reduction in pathogenicity on potato tubers and leaves of potato plant.",A R Khalid 2019,2019,1 gene,Khalid-2019-Role of Autophagy-Related Gene atg,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14049,PHI:9192,UniProt,A0A0D2X8F5,GenBank,KNA93804,,,4287,Foatg22,chromosome 1,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,tuber; leaf,ubiquitin-like protein,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31086099,PubMed,10.3390/genes10050365,Genes (Basel). 2019 May 13;10(5),haseeb78692@yahoo.com,"ΔFoatg22 strains exhibited a decrease in hyphal development and conidiation, and reduction in pathogenicity on potato tubers and leaves of potato plant.",A R Khalid 2019,2019,1 gene,Khalid-2019-Role of Autophagy-Related Gene atg,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14050,PHI:9193,UniProt,E9ETR6,GenBank,EFZ00819,,,ARSEF 23,MrArk1 (MAA_03415),,,,,,,176275,Beauveria bassiana,568076,ARSEF 2575,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,actin-regulatingkinase,,,,reduced virulence,,yes,yes,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31025075,PubMed,10.1007/s00253-019-09836-6,Appl Microbiol Biotechnol. 2019 Jun;103(12):4859-4868,bhuang@ahau.edu.cn,"The deletion mutant showed a significant decrease in its tolerance to heat shock, but not to UV-B irradiation.",Z Wang 2019,2019,1 gene,"Wang-2019-MrArk1, an actin-regulating kinase g",BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14051,PHI:9194,UniProt,M2UKY5,JGI,1110585,,,,ste20,,,,,,,5016,Bipolaris maydis,,HITO7711,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. Takanestar,,,leaf,PAK (p21-activated protein kinases)-like kinase,,,,unaffected pathogenicity,,no,no,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,31028454,PubMed,10.1007/s00294-019-00977-9,Curr Genet. 2019 Apr 26,chihiro@kais.kyoto-u.ac.jp,"Ste20 was partially involved in pseudothecium development but was dispensable for maternity, while Cla4 was essential for maternal pseudothecium development and also involved in ascospore development in paternal pseudothecium.",Y Kitade 2019,2019,2 genes,Kitade-2019-Cla4 PAK-like kinase is required f,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14052,PHI:9195,UniProt,M2UDZ5,JGI,32463,,,,cla4,,,,,,,5016,Bipolaris maydis,,HITO7711,southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. Takanestar,,,leaf,PAK (p21-activated protein kinases)-like kinase,,,,reduced virulence,,yes,no,,,reduced; aberrant,reduced,reduced,wild type,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,31028454,PubMed,10.1007/s00294-019-00977-9,Curr Genet. 2019 Apr 26,chihiro@kais.kyoto-u.ac.jp,"Ste20 was partially involved in pseudothecium development but was dispensable for maternity, while Cla4 was essential for maternal pseudothecium development and also involved in ascospore development in paternal pseudothecium.",Y Kitade 2019,2019,2 genes,Kitade-2019-Cla4 PAK-like kinase is required f,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14053,PHI:9196,UniProt,A0A063CBJ7,,,,,,SCRE2 (UV_1261),,,,,,,1159556,Ustilaginoidea virens,,P1,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Liangyoupeijiu 9,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,31105658,PubMed,10.3389/fmicb.2019.00845,Front Microbiol. 2019 Apr 24;10:845,wxs@cau.edu.cn,Ectopic expression of SCRE2 in the transgenic rice cells significantly inhibited pathogen-associated molecular pattern-triggered immunity including flg22- and chitin-induced defense gene expression and oxidative burst.,A Fang 2019,2019,1 gene,Fang-2019-A Novel Effector Gene SCRE2 Contribu,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14054,PHI:9196,UniProt,A0A063CBJ7,,,,,,SCRE2 (UV_1261),,,,,,,1159556,Ustilaginoidea virens,,P1,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Liangyoupeijiu 9,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31105658,PubMed,10.3389/fmicb.2019.00845,Front Microbiol. 2019 Apr 24;10:845,wxs@cau.edu.cn,The scre2 knockout mutant generated by the CRISPR/Cas9 system greatly attenuated in U. virens virulence to rice.,A Fang 2019,2019,1 gene,Fang-2019-A Novel Effector Gene SCRE2 Contribu,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14055,PHI:9196,UniProt,A0A063CBJ7,,,,,,SCRE2 (UV_1261),,,,,,,1159556,Ustilaginoidea virens,,P1,false smut (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31105658,PubMed,10.3389/fmicb.2019.00845,Front Microbiol. 2019 Apr 24;10:845,wxs@cau.edu.cn,Transient expression of SCRE2 in Nicotiana benthamiana suppressed necrosis-like defense symptoms triggered by the mammalian BAX and oomycete elicitin INF1 proteins.,A Fang 2019,2019,1 gene,Fang-2019-A Novel Effector Gene SCRE2 Contribu,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14056,PHI:9197,UniProt,Q8X6L3,GenBank,AE005571_13,,,EDL933,z4861,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,ciprofloxacin; levofloxacin,ciprofloxacin: CHEBI:100241; levofloxacin: CHEBI:63598,,,,,gene deletion: full,,,YVS,31019555,PubMed,10.1186/s13099-019-0296-7,Gut Pathog. 2019 Apr 18;11:15,ramy.aziz@salmonella.org,Knocking out mmpL-like genes showed slight differences in adhesion of the WT and mutant either on epithelial colon cells (Caco-2 cell line) or on biofilm formation that were not statistically significant.,S H Hussein 2019,2019,2 genes,Hussein-2019-Two putative MmpL homologs contri,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14057,PHI:9198,UniProt,W8ZK20,GenBank,CDN82752,,,EC958,yegN,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,multidrug efflux system subunit,,,,reduced virulence,,,,,,,,wild type,,no,ciprofloxacin; levofloxacin,ciprofloxacin: CHEBI:100241; levofloxacin: CHEBI:63598,,,,,gene deletion: full,,,YVS,31019555,PubMed,10.1186/s13099-019-0296-7,Gut Pathog. 2019 Apr 18;11:15,ramy.aziz@salmonella.org,Knocking out mmpL-like genes showed slight differences in adhesion of the WT and mutant either on epithelial colon cells (Caco-2 cell line) or on biofilm formation that were not statistically significant.,S H Hussein 2019,2019,2 genes,Hussein-2019-Two putative MmpL homologs contri,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14058,PHI:9197,UniProt,Q8X6L3,GenBank,AE005571_13,,,EDL933,z4861,,,,,,PHI:9198,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,ciprofloxacin; levofloxacin,ciprofloxacin: CHEBI:100241; levofloxacin: CHEBI:63598,,,,,gene deletion: full,,,YVS,31019555,PubMed,10.1186/s13099-019-0296-7,Gut Pathog. 2019 Apr 18;11:15,ramy.aziz@salmonella.org,Knocking out mmpL-like genes showed slight differences in adhesion of the WT and mutant either on epithelial colon cells (Caco-2 cell line) or on biofilm formation that were not statistically significant.,S H Hussein 2019,2019,2 genes,Hussein-2019-Two putative MmpL homologs contri,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14059,PHI:9198,UniProt,W8ZK20,GenBank,CDN82752,,,EC958,yegN,,,,,,PHI:9197,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,multidrug efflux system subunit,,,,reduced virulence,,,,,,,,wild type,,no,ciprofloxacin; levofloxacin,ciprofloxacin: CHEBI:100241; levofloxacin: CHEBI:63598,,,,,gene deletion: full,,,YVS,31019555,PubMed,10.1186/s13099-019-0296-7,Gut Pathog. 2019 Apr 18;11:15,ramy.aziz@salmonella.org,Knocking out mmpL-like genes showed slight differences in adhesion of the WT and mutant either on epithelial colon cells (Caco-2 cell line) or on biofilm formation that were not statistically significant.,S H Hussein 2019,2019,2 genes,Hussein-2019-Two putative MmpL homologs contri,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14060,PHI:9199,UniProt,G4NC35,GenBank,EHA49038,,,70-15,MoCKb1 (MGG_00446),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,serine/threonine kinase regulatory subunit,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31058100,PubMed,10.3389/fcimb.2019.00113,Front Cell Infect Microbiol. 2019 Apr 17;9:113,wangzh@fafu.edu.cn,CK2 holoenzyme needed to be intact for normal localization at septal pores and at appressorium penetration pores.,L Zhang 2019,2019,3 genes,Zhang-2019-Magnaporthe oryzae CK2 Accumulates,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14061,PHI:9200,UniProt,G4MNM6,GenBank,EHA57932,,,70-15,MoCKb2 (MGG_05651),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,serine/threonine kinase regulatory subunit,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31058100,PubMed,10.3389/fcimb.2019.00113,Front Cell Infect Microbiol. 2019 Apr 17;9:113,wangzh@fafu.edu.cn,CK2 holoenzyme needed to be intact for normal localization at septal pores and at appressorium penetration pores.,L Zhang 2019,2019,3 genes,Zhang-2019-Magnaporthe oryzae CK2 Accumulates,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14062,PHI:9199,UniProt,G4NC35,GenBank,EHA49038,,,70-15,MoCKb1 (MGG_00446),chromosome 5,GFP-MoCKb1 fusion protein,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,serine/threonine kinase regulatory subunit,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31058100,PubMed,10.3389/fcimb.2019.00113,Front Cell Infect Microbiol. 2019 Apr 17;9:113,wangzh@fafu.edu.cn,CK2 holoenzyme needed to be intact for normal localization at septal pores and at appressorium penetration pores.,L Zhang 2019,2019,3 genes,Zhang-2019-Magnaporthe oryzae CK2 Accumulates,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14063,PHI:9200,UniProt,G4MNM6,GenBank,EHA57932,,,70-15,MoCKb2 (MGG_05651),chromosome 1,GFP-MoCKb2 fusion protein,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,serine/threonine kinase regulatory subunit,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31058100,PubMed,10.3389/fcimb.2019.00113,Front Cell Infect Microbiol. 2019 Apr 17;9:113,wangzh@fafu.edu.cn,CK2 holoenzyme needed to be intact for normal localization at septal pores and at appressorium penetration pores.,L Zhang 2019,2019,3 genes,Zhang-2019-Magnaporthe oryzae CK2 Accumulates,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14064,PHI:9201,UniProt,G4N6P9,GenBank,EHA49866,,,70-15,MoCKa1 (MGG_03696),chromosome 4,GFP-MoCKa fusion protein,,,,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,CMGC/CK2 protein kinase catalytic subunit,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31058100,PubMed,10.3389/fcimb.2019.00113,Front Cell Infect Microbiol. 2019 Apr 17;9:113,wangzh@fafu.edu.cn,CK2 holoenzyme needed to be intact for normal localization at septal pores and at appressorium penetration pores.,L Zhang 2019,2019,3 genes,Zhang-2019-Magnaporthe oryzae CK2 Accumulates,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14065,PHI:9202,UniProt,B8QGZ7,GenBank,ACD67884,,,CP24-03,delta toxin,,,,,,,1502,Clostridium perfringens,,,intestinal disease,rodents,10090,Mus musculus (related: house mouse),ICR,,,small intestine,secreted pore-forming delta-toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,31013617,PubMed,10.3390/toxins11040232.,Toxins (Basel). 2019 Apr 22;11(4).,kobakei@ph.bunri-u.ac.jp,Delta-toxin induced intestinal epithelium injury caused by the loss of E-cadherin digested by ADAM10 activation.,S Seike 2019,2019,1 gene,Seike-2019-Clostridium perfringens Delta-Toxin,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14066,PHI:9203,UniProt,Q4WQF6,GenBank,EAL89528,,,Af293,gcnE (AFUA 4g12650),chromosome 4,,,,,,746128,Aspergillus fumigatus,,akuBKU80,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced; aberrant,,no,H2O2; sodium dodecyl sulfate (SDS); Congo red; LiCl; menadione,H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653; LiCl: CHEBI:48607; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,31100153,PubMed,10.1093/mmy/myz043,Med Mycol. 2019 May 17,ychen28@ntu.edu.tw,GcnE was critical for conidiation and biofilm formation but not virulence in A. fumigatus.,C J Lin 2019,2019,1 gene,Lin-2019-The histone acetyltransferase GcnE re,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14067,PHI:9204,UniProt,A0A0D1E4M7,GenBank,KIS69395,,,521,Spp1 (UMAG_02729),chromosome 6,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,signal peptide peptidase,,,,loss of pathogenicity,,no,no,yes,,,,wild type,,no,diphenyleneiodonium,diphenyleneiodonium: CHEBI:77986,,,,,gene mutation; gene complementation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,Proliferation of fungal hyphae after plant penetration was highly reduced in ΔSpp1 strain.,N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14068,PHI:9204,UniProt,A0A0D1E4M7,GenBank,KIS69395,,,521,Spp1 (UMAG_02729),chromosome 6,D279A,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,signal peptide peptidase,,,,loss of pathogenicity,,,,,,,,wild type,,no,diphenyleneiodonium,diphenyleneiodonium: CHEBI:77986,,,,,gene mutation; gene complementation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,Proliferation of fungal hyphae after plant penetration was highly reduced in ΔSpp1 strain.,N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14069,PHI:9205,UniProt,A0A0D1D175,GenBank,KIS72123,,,521,Hrd1 (UMAG_00542),chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,ubiquitin protein ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14070,PHI:9206,UniProt,A0A0D1CL60,GenBank,KIS67488,,,521,Doa10 (UMAG_10911),chromosome 13,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,ubiquitin protein ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14071,PHI:9207,UniProt,A0A0D1DU92,GenBank,KIS66160,,,521,Der1 (UMAG_05898),chromosome 20,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,Derlin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14072,PHI:9208,UniProt,A0A0D1E0M1,GenBank,KIS69759,,,521,Der2 (UMAG_11402),chromosome 5,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,Derlin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14073,PHI:9205,UniProt,A0A0D1D175,GenBank,KIS72123,,,521,Hrd1 (UMAG_00542),chromosome 1,,,,,PHI:9206,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,ubiquitin protein ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14074,PHI:9206,UniProt,A0A0D1CL60,GenBank,KIS67488,,,521,Doa10 (UMAG_10911),chromosome 13,,,,,PHI:9205,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,ubiquitin protein ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14075,PHI:9205,UniProt,A0A0D1D175,GenBank,KIS72123,,,521,Hrd1 (UMAG_00542),chromosome 1,,,,,PHI:9206; PHI:9207,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,ubiquitin protein ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14076,PHI:9206,UniProt,A0A0D1CL60,GenBank,KIS67488,,,521,Doa10 (UMAG_10911),chromosome 13,,,,,PHI:9205; PHI:9207,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,ubiquitin protein ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14077,PHI:9207,UniProt,A0A0D1DU92,GenBank,KIS66160,,,521,Der1 (UMAG_05898),chromosome 20,,,,,PHI:9205; PHI:9206,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,Derlin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14078,PHI:9205,UniProt,A0A0D1D175,GenBank,KIS72123,,,521,Hrd1 (UMAG_00542),chromosome 1,,,,,PHI:9206; PHI:9208,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,ubiquitin protein ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14079,PHI:9206,UniProt,A0A0D1CL60,GenBank,KIS67488,,,521,Doa10 (UMAG_10911),chromosome 13,,,,,PHI:9205; PHI:9208,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,ubiquitin protein ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14080,PHI:9208,UniProt,A0A0D1E0M1,GenBank,KIS69759,,,521,Der2 (UMAG_11402),chromosome 5,,,,,PHI:9205; PHI:9206,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,Derlin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,"Neither ER stress resistance nor virulence was affected in any of the single, double or triple mutants of genes encoding the conserved ERAD components.",N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14081,PHI:9209,UniProt,A0A0D1DRD3,GenBank,KIS66939,,,521,srb1 (UMAG_05721),chromosome 16,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,putative sterol regulatory element binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,Neither ER stress resistance nor virulence was affected in srb1 deletion mutant.,N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14082,PHI:9210,UniProt,A0A0D1E942,GenBank,KIS72379,,,521,UMAG_00783,chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,heme oxygenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30998787,PubMed,10.1371/journal.ppat.1007734,PLoS Pathog. 2019 Apr 18;15(4):e1007734,kheimel@gwdg.de,Virulence defect of Spp1 mutants was not related to the function of heme oxygenase (UMAG_00783).,N Pinter 2019,2019,7 genes,Pinter-2019-Signal peptide peptidase activity,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14083,PHI:9211,UniProt,G5EI20,GenBank,ACQ73209,,,70-15,BAS4,chromosome VI,,,,,,318829,Magnaporthe oryzae,,A1343R-7,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,extrainvasive hyphal membrane matrix protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31049006,PubMed,10.1016/j.sjbs.2019.01.003,Saudi J Biol Sci. 2019 May;26(4):795-807,yangjin-18@163.com,More serious blast disease symptom and more biomass also appeared in lesion of leaves inoculated with BAS4-overexpressed strain than those of leaves inoculated with the wild-type strain and expression level of pathogenicity-related genes appeared lower in biotrophic phase and higher in necrotrophic phase of infection.,C Wang 2019,2019,1 gene,Wang-2019-The biotrophy-associated secreted pr,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14084,PHI:9212,UniProt,A7E9D9,GenBank,EDN96991,,,1980,SsSvf1 (SS1G_01919),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia,,,leaf,survival factor 1,,,,reduced virulence,,yes,,,,,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,altered gene expression / gene regulation: silencing,,,YVS,31074170,PubMed,10.1111/mpp.12801,Mol Plant Pathol. 2019 May 9,jiasencheng@mail.hzau.edu.cn,Silencing of SsSvf1 resulted in increased sensitivity to oxidative stress in culture and increased levels of intracellular ROS.,Y Yu 2019,2019,1 gene,Yu-2019-Survival factor 1 contributes to the o,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14085,PHI:9212,UniProt,A7E9D9,GenBank,EDN96991,,,1980,SsSvf1 (SS1G_01919),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),cv. Zhongyou 821,,,leaf,survival factor 1,,,,reduced virulence,,yes,,,,,,,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,altered gene expression / gene regulation: silencing,,,YVS,31074170,PubMed,10.1111/mpp.12801,Mol Plant Pathol. 2019 May 9,jiasencheng@mail.hzau.edu.cn,Silencing of SsSvf1 resulted in increased sensitivity to oxidative stress in culture and increased levels of intracellular ROS.,Y Yu 2019,2019,1 gene,Yu-2019-Survival factor 1 contributes to the o,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14086,PHI:9213,UniProt,P49988,GenBank,AE004860_6,,,PAO1,RpoN,,,,,,,287,Pseudomonas aeruginosa,,SCH0057-7,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cis-acting peptide of RNA polymerase sigma-54 factor,,,,reduced virulence,,,,,,,,,,no,gentamicin; cefotaxime; cefepime; ceftazidime; piperacillin; imipenem,gentamicin: CHEBI:17833; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; ceftazidime: CHEBI:3508; piperacillin: CHEBI:8232; imipenem: CHEBI:471744,,,,,"other evidence: P. aeruginosa CF isolate SCH0057-7 transformed with cis-acting peptide, RpoN*-expression vector",,,YVS,31040330,PubMed,10.1038/s41598-019-43060-6,Sci Rep. 2019 Apr 30;9(1):6677,moffatj@upstate.edu,"Cis-acting peptide, RpoN* expression reduced motility, biofilm formation and pathogenesis in a P. aeruginosa-C. elegans infection model.",M G Lloyd 2019,2019,1 gene,Lloyd-2019-Blocking RpoN reduces virulence of,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14087,PHI:9214,UniProt,A0A0E0UWL3,GenBank,AEH92837,,,M7,virR,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,putative two-component response regulator,,,,reduced virulence,,,,,,,,,,no,nisin; baciracin; triton X-100,nisin: CHEBI:71629; bacitracin: CHEBI:28669; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,29263107,PubMed,10.1128/IAI.00901-17,Infect Immun. 2018 Feb 20;86(3),darren_higgins@hms.harvard.edu,ΔVirR and ΔvirAB mutants were defective in cell-to-cell spread due to a lower average movement rate of intracellular bacteria.,D Grubaugh 2017,2017,3 genes,Grubaugh-2017-The VirAB ABC transporter is req,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14088,PHI:9215,UniProt,Q8Y6E1,GenBank,CAC99824,,,EGD-e,virA (lmo1746),,,,,,PHI:9216,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,ABC transporter,,,,reduced virulence,,,,,,,,,,no,nisin; baciracin; triton X-100,nisin: CHEBI:71629; bacitracin: CHEBI:28669; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,29263107,PubMed,10.1128/IAI.00901-17,Infect Immun. 2018 Feb 20;86(3),darren_higgins@hms.harvard.edu,ΔVirR and ΔvirAB mutants were defective in cell-to-cell spread due to a lower average movement rate of intracellular bacteria.,D Grubaugh 2017,2017,3 genes,Grubaugh-2017-The VirAB ABC transporter is req,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14089,PHI:9216,UniProt,Q8Y6E0,GenBank,CAC99825,,,EGD-e,virB (lmo1747),,,,,,PHI:9215,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,ABC transporter,,,,reduced virulence,,,,,,,,,,no,nisin; baciracin; triton X-100,nisin: CHEBI:71629; bacitracin: CHEBI:28669; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,29263107,PubMed,10.1128/IAI.00901-17,Infect Immun. 2018 Feb 20;86(3),darren_higgins@hms.harvard.edu,ΔVirR and ΔvirAB mutants were defective in cell-to-cell spread due to a lower average movement rate of intracellular bacteria.,D Grubaugh 2017,2017,3 genes,Grubaugh-2017-The VirAB ABC transporter is req,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14090,PHI:9214,UniProt,A0A0E0UWL3,GenBank,AEH92837,,,M7,virR,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),L2 cell line,,,fibroblast cell line,putative two-component response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,nisin; baciracin; triton X-100,nisin: CHEBI:71629; bacitracin: CHEBI:28669; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,29263107,PubMed,10.1128/IAI.00901-17,Infect Immun. 2018 Feb 20;86(3),darren_higgins@hms.harvard.edu,ΔVirR and ΔvirAB mutants were defective in cell-to-cell spread due to a lower average movement rate of intracellular bacteria.,D Grubaugh 2017,2017,3 genes,Grubaugh-2017-The VirAB ABC transporter is req,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14091,PHI:9215,UniProt,Q8Y6E1,GenBank,CAC99824,,,EGD-e,virA (lmo1746),,,,,,PHI:9216,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),L2 cell line,,,fibroblast cell line,ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,no,nisin; baciracin; triton X-100,nisin: CHEBI:71629; bacitracin: CHEBI:28669; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,29263107,PubMed,10.1128/IAI.00901-17,Infect Immun. 2018 Feb 20;86(3),darren_higgins@hms.harvard.edu,ΔVirR and ΔvirAB mutants were defective in cell-to-cell spread due to a lower average movement rate of intracellular bacteria.,D Grubaugh 2017,2017,3 genes,Grubaugh-2017-The VirAB ABC transporter is req,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14092,PHI:9216,UniProt,Q8Y6E0,GenBank,CAC99825,,,EGD-e,virB (lmo1747),,,,,,PHI:9215,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),L2 cell line,,,fibroblast cell line,ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,no,nisin; baciracin; triton X-100,nisin: CHEBI:71629; bacitracin: CHEBI:28669; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,29263107,PubMed,10.1128/IAI.00901-17,Infect Immun. 2018 Feb 20;86(3),darren_higgins@hms.harvard.edu,ΔVirR and ΔvirAB mutants were defective in cell-to-cell spread due to a lower average movement rate of intracellular bacteria.,D Grubaugh 2017,2017,3 genes,Grubaugh-2017-The VirAB ABC transporter is req,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14093,PHI:9214,UniProt,A0A0E0UWL3,GenBank,AEH92837,,,M7,virR,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,putative two-component response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,nisin; baciracin; triton X-100,nisin: CHEBI:71629; bacitracin: CHEBI:28669; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,29263107,PubMed,10.1128/IAI.00901-17,Infect Immun. 2018 Feb 20;86(3),darren_higgins@hms.harvard.edu,ΔVirR and ΔvirAB mutants were defective in cell-to-cell spread due to a lower average movement rate of intracellular bacteria.,D Grubaugh 2017,2017,3 genes,Grubaugh-2017-The VirAB ABC transporter is req,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14094,PHI:9215,UniProt,Q8Y6E1,GenBank,CAC99824,,,EGD-e,virA (lmo1746),,,,,,PHI:9216,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,no,nisin; baciracin; triton X-100,nisin: CHEBI:71629; bacitracin: CHEBI:28669; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,29263107,PubMed,10.1128/IAI.00901-17,Infect Immun. 2018 Feb 20;86(3),darren_higgins@hms.harvard.edu,ΔVirR and ΔvirAB mutants were defective in cell-to-cell spread due to a lower average movement rate of intracellular bacteria.,D Grubaugh 2017,2017,3 genes,Grubaugh-2017-The VirAB ABC transporter is req,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14095,PHI:9216,UniProt,Q8Y6E0,GenBank,CAC99825,,,EGD-e,virB (lmo1747),,,,,,PHI:9215,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,no,nisin; baciracin; triton X-100,nisin: CHEBI:71629; bacitracin: CHEBI:28669; Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,29263107,PubMed,10.1128/IAI.00901-17,Infect Immun. 2018 Feb 20;86(3),darren_higgins@hms.harvard.edu,ΔVirR and ΔvirAB mutants were defective in cell-to-cell spread due to a lower average movement rate of intracellular bacteria.,D Grubaugh 2017,2017,3 genes,Grubaugh-2017-The VirAB ABC transporter is req,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14096,PHI:9217,UniProt,I1RFJ3,GenBank,CEF74768,,,PH-1,FgMed1,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,transcription factor,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,reduced,reduced,reduced,,no,sorbitol; NaCl; H2O2; CFW; SDS; Congo red,sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31115634,PubMed,10.1007/s00253-019-09872-2,Appl Microbiol Biotechnol. 2019 May 21,gdlufafu@163.com,"DON production, assayed in rice grain cultures, showed that ΔFgMed1 mutants have a very low level of DON than the wild-type.",G Fan 2019,2019,1 gene,Fan-2019-The transcription factor FgMed1 is in,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14097,PHI:9218,UniProt,B8NRT5,GenBank,EED47023,,,NRRL3357,ppci1 (AFLA_050760),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,peptidyl-prolyl cis-trans isomerase,,,,increased virulence (hypervirulence),,,,,,increased,,reduced,,no,tacrolimus (FK506); cyclosporin A (CsA); rapamycin (rap); N-ethylmaleimide (NEM),tacrolimus (FK506): CHEBI:61049; cyclosporin A (CsA): CHEBI:4031; rapamycin (Rap): CHEBI:9168; N-ethylmaleimide (NEM): CHEBI:44485,,,,,gene deletion: full; gene complementation,,,YVS,31060313,PubMed,10.3390/ijms20092206,Int J Mol Sci. 2019 May 5;20(9),elitumu09@yahoo.fr,A. flavus growth and sclerotia formation were reduced and conidiation was increased in Δppci1 compared with the wild-type.,S Ahmad 2019,2019,1 gene,Ahmad-2019-Functional Analysis of Peptidyl-pro,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14098,PHI:9219,UniProt,B8NGC8,GenBank,EED50705,,,NRRL3357,creA (AFLA_134680),,,,,,,5059,Aspergillus flavus,,,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,"C2H2 transcription factor, carbon catabolite repression protein",,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,NaCl; KCl; CFW; SDS; MMS,NaCl: CHEBI:26710; KCl: CHEBI:32588; CFW: CHEBI:50011; SDS: CHEBI:8984; methyl methanesulfonate: CHEBI:25255,,,,,gene deletion: full,,,YVS,29655909,PubMed,10.1016/j.fgb.2018.04.008,Fungal Genet Biol. 2018 Jun;115:41-51,wshyyl@sina.com,"ΔCreA produced insignificant amount of aflatoxin in complete medium, and its ability to colonize hosts was also impaired.",O E Fasoyin 2018,2018,1 gene,Esther Fasoyin-2018-Carbon catabolite repressi,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14099,PHI:9219,UniProt,B8NGC8,GenBank,EED50705,,,NRRL3357,creA (AFLA_134680),,,,,,,5059,Aspergillus flavus,,,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,"C2H2 transcription factor, carbon catabolite repression protein",,,aflatoxin biosynthesis,increased virulence (hypervirulence),,,,,,increased,,wild type,,no,NaCl; KCl; CFW; SDS; MMS,NaCl: CHEBI:26710; KCl: CHEBI:32588; CFW: CHEBI:50011; SDS: CHEBI:8984; methyl methanesulfonate: CHEBI:25255,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29655909,PubMed,10.1016/j.fgb.2018.04.008,Fungal Genet Biol. 2018 Jun;115:41-51,wshyyl@sina.com,"ΔCreA produced insignificant amount of aflatoxin in complete medium, and its ability to colonize hosts was also impaired.",O E Fasoyin 2018,2018,1 gene,Esther Fasoyin-2018-Carbon catabolite repressi,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14100,PHI:9219,UniProt,B8NGC8,GenBank,EED50705,,,NRRL3357,creA (AFLA_134680),,,,,,,5059,Aspergillus flavus,,,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,"C2H2 transcription factor, carbon catabolite repression protein",,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,NaCl; KCl; CFW; SDS; MMS,NaCl: CHEBI:26710; KCl: CHEBI:32588; CFW: CHEBI:50011; SDS: CHEBI:8984; methyl methanesulfonate: CHEBI:25255,,,,,gene deletion: full,,,YVS,29655909,PubMed,10.1016/j.fgb.2018.04.008,Fungal Genet Biol. 2018 Jun;115:41-51,wshyyl@sina.com,"ΔCreA produced insignificant amount of aflatoxin in complete medium, and its ability to colonize hosts was also impaired.",O E Fasoyin 2018,2018,1 gene,Esther Fasoyin-2018-Carbon catabolite repressi,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14101,PHI:9219,UniProt,B8NGC8,GenBank,EED50705,,,NRRL3357,creA (AFLA_134680),,,,,,,5059,Aspergillus flavus,,,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,"C2H2 transcription factor, carbon catabolite repression protein",,,aflatoxin biosynthesis,increased virulence (hypervirulence),,,,,,increased,,wild type,,no,NaCl; KCl; CFW; SDS; MMS,NaCl: CHEBI:26710; KCl: CHEBI:32588; CFW: CHEBI:50011; SDS: CHEBI:8984; methyl methanesulfonate: CHEBI:25255,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29655909,PubMed,10.1016/j.fgb.2018.04.008,Fungal Genet Biol. 2018 Jun;115:41-51,wshyyl@sina.com,"ΔCreA produced insignificant amount of aflatoxin in complete medium, and its ability to colonize hosts was also impaired.",O E Fasoyin 2018,2018,1 gene,Esther Fasoyin-2018-Carbon catabolite repressi,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14102,PHI:9220,UniProt,A0A482CLE6,GenBank,QBL89733,,,abta14,AbSte7 (MH559277),,,,,,,29001,Alternaria brassicicola,,abta14,black spot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,mitogen-activated protein kinase kinase,,,,reduced virulence,,,,,,aberrant,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,31007639,PubMed,10.5423/PPJ.OA.07.2018.0125,Plant Pathol J. 2019 Apr;35(2):91-99,khbaek@ynu.ac.kr,Disruption of the AbSte7 gene also severely impaired fungal detoxification of reactive oxygen species and could not efficiently detoxify cruciferous phytoalexin brassinin.,K Lu 2019,2019,1 gene,Lu-2019-The MAP Kinase Kinase Gene AbSte7 Regu,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14103,PHI:9221,,no data found,GenBank,ARV23137,,,12-2,ompA (A9D66_11115),,,,,,,53413,Xanthomonas axonopodis,,pv. glycines strain KU-P-SW005,bacterial blight,eudicots,3847,Glycine max (related: soybean),cv. Spencer,,,leaf,outer membrane or secreted lipoprotein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31089795,PubMed,10.1007/s00284-019-01702-y,Curr Microbiol. 2019 May 14,athinova6@hotmail.com,"Multiple defects were caused in the ompA mutant including altered biofilm formation, decreased cellulase and pectase lyase activity, reduced polysaccharide production, and possibly reduced adhesion and motility.",D Athinuwat 2019,2019,1 gene,Athinuwat-2019-The OmpA Gene of Xanthomonas ax,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14104,PHI:9222,UniProt,I1RSI3,GenBank,CEF83248,,,PH-1,FgPEX1 (FGSG_07104),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,inflorescence,peroxin,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,H2O2; SDS; Congo red,H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31111312,PubMed,10.1007/s00294-019-00994-8,Curr Genet. 2019 May 20,jfyu@sdau.edu.cn,"Both mutants displayed reduced mycelial growth, conidiation and production of perithecia.",L Zhang 2019,2019,2 genes,Zhang-2019-FgPEX1 and FgPEX10 are required for,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14105,PHI:9223,UniProt,I1RSG0,GenBank,CEF85647,,,PH-1,FgPEX10 (FGSG_07078),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,inflorescence,peroxin,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,H2O2; SDS; Congo red,H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31111312,PubMed,10.1007/s00294-019-00994-8,Curr Genet. 2019 May 20,jfyu@sdau.edu.cn,"Both mutants displayed reduced mycelial growth, conidiation and production of perithecia.",L Zhang 2019,2019,2 genes,Zhang-2019-FgPEX1 and FgPEX10 are required for,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14106,PHI:9222,UniProt,I1RSI3,GenBank,CEF83248,,,PH-1,FgPEX1 (FGSG_07104),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,peroxin,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,H2O2; SDS; Congo red,H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31111312,PubMed,10.1007/s00294-019-00994-8,Curr Genet. 2019 May 20,jfyu@sdau.edu.cn,"Both mutants displayed reduced mycelial growth, conidiation and production of perithecia.",L Zhang 2019,2019,2 genes,Zhang-2019-FgPEX1 and FgPEX10 are required for,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14107,PHI:9223,UniProt,I1RSG0,GenBank,CEF85647,,,PH-1,FgPEX10 (FGSG_07078),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,peroxin,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,reduced,no,H2O2; SDS; Congo red,H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31111312,PubMed,10.1007/s00294-019-00994-8,Curr Genet. 2019 May 20,jfyu@sdau.edu.cn,"Both mutants displayed reduced mycelial growth, conidiation and production of perithecia.",L Zhang 2019,2019,2 genes,Zhang-2019-FgPEX1 and FgPEX10 are required for,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14108,PHI:9224,UniProt,Q5AK01,GenBank,AOW29930,,,SC5314,CaPsy4,chromosome 5,,,CaPsy2; CaPph3,UniProt: A0A1D8PCN8; GenBank: AOW25913; UniProt: A0A1D8PSJ8; GenBank: AOW31118,,5476,Candida albicans,,RM1000,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,methyl methanesulfonate (MMS); hydroxyurea (HU); cisplatin (CP),methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea (HU): CHEBI:44423; cisplatin (CP): CHEBI:27899,,,,,gene deletion: full; gene complementation,,,YVS,28967545,PubMed,10.1016/j.ijmm.2017.09.017,Int J Med Microbiol. 2017 Dec;307(8):471-480,linghuojiang@hotmail.com,Deletion of CaPSY4 caused C. albicans cells a sensitivity to genotoxic reagents and a defect in DNA damage-induced filamentation.,J Feng 2017,2017,3 genes,Feng-2017-The N-terminal pY33XL motif of CaPsy,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14109,PHI:9225,UniProt,A0A1D8PCN8,GenBank,AOW25913,,,SC5314,CaPsy2,chromosome 1,,,CaPsy4; CaPph3,UniProt: Q5AK01; GenBank: AOW29930; UniProt: A0A1D8PSJ8; GenBank: AOW31118,,5476,Candida albicans,,RM1000,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphoprotein phosphatase PP4 regulatory subunit,,,,increased virulence (hypervirulence),,,,,,,,,,no,methyl methanesulfonate (MMS); hydroxyurea (HU); cisplatin (CP),methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea (HU): CHEBI:44423; cisplatin (CP): CHEBI:27899,,,,,gene deletion: full; gene complementation,,,YVS,28967545,PubMed,10.1016/j.ijmm.2017.09.017,Int J Med Microbiol. 2017 Dec;307(8):471-480,linghuojiang@hotmail.com,"C. albicans cells lacking CaPPH3, CaPSY2 or CaPSY4 and C. albicans cells carrying the Y33A mutation of CaPSY2, show increased virulence to mice.",J Feng 2017,2017,3 genes,Feng-2017-The N-terminal pY33XL motif of CaPsy,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14110,PHI:9225,UniProt,A0A1D8PCN8,GenBank,AOW25913,,,SC5314,CaPsy2,chromosome 1,Y33A,,CaPsy4; CaPph3,UniProt: Q5AK01; GenBank: AOW29930; UniProt: A0A1D8PSJ8; GenBank: AOW31118,,5476,Candida albicans,,RM1000,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphoprotein phosphatase PP4 regulatory subunit,,,,increased virulence (hypervirulence),,,,,,,,,,no,methyl methanesulfonate (MMS); hydroxyurea (HU); cisplatin (CP),methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea (HU): CHEBI:44423; cisplatin (CP): CHEBI:27899,,,,,gene deletion: full; gene complementation,,,YVS,28967545,PubMed,10.1016/j.ijmm.2017.09.017,Int J Med Microbiol. 2017 Dec;307(8):471-480,linghuojiang@hotmail.com,"C. albicans cells lacking CaPPH3, CaPSY2 or CaPSY4 and C. albicans cells carrying the Y33A mutation of CaPSY2, show increased virulence to mice.",J Feng 2017,2017,3 genes,Feng-2017-The N-terminal pY33XL motif of CaPsy,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14111,PHI:9226,UniProt,A0A1D8PSJ8,GenBank,AOW31118,,,SC5314,CaPph3,,,,CaPsy4; CaPsy2,UniProt: Q5AK01; GenBank: AOW29930; UniProt: A0A1D8PCN8; GenBank: AOW25913,,5476,Candida albicans,,RM1000,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphoprotein phosphatase PP4 catalytic subunit,,,,increased virulence (hypervirulence),,,,,,,,,,no,methyl methanesulfonate (MMS); hydroxyurea (HU); cisplatin (CP),methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea (HU): CHEBI:44423; cisplatin (CP): CHEBI:27899,,,,,gene deletion: full; gene complementation,,,YVS,28967545,PubMed,10.1016/j.ijmm.2017.09.017,Int J Med Microbiol. 2017 Dec;307(8):471-480,linghuojiang@hotmail.com,"C. albicans cells lacking CaPPH3, CaPSY2 or CaPSY4 and C. albicans cells carrying the Y33A mutation of CaPSY2, show increased virulence to mice.",J Feng 2017,2017,3 genes,Feng-2017-The N-terminal pY33XL motif of CaPsy,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14112,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,PHI:9228; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14113,PHI:9228,UniProt,P0AF54,GenBank,AAC77038,,,K-12,yjcH,,,,,,PHI:9227; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,conserved inner membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14114,PHI:9229,UniProt,P32705,GenBank,AAC77037,,,K-12,actP,,,,,,PHI:9227; PHI:9228,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,acetate/glycolate:cation symporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14115,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14116,PHI:9229,UniProt,P32705,GenBank,AAC77037,,,K-12,actP,,,,,,,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,acetate/glycolate:cation symporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14117,PHI:9230,UniProt,P0AC98,GenBank,AAC73121,,,K-12,satP,,,,,,,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,succinate-acetate/proton symporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14118,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,,562,Escherichia coli,,FY26,avian colisepticemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14119,PHI:9229,UniProt,P32705,GenBank,AAC77037,,,K-12,actP,,,,,,,562,Escherichia coli,,FY26,avian colisepticemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,acetate/glycolate:cation symporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14120,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,PHI:9228; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14121,PHI:9228,UniProt,P0AF54,GenBank,AAC77038,,,K-12,yjcH,,,,,,PHI:9227; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,conserved inner membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14122,PHI:9229,UniProt,P32705,GenBank,AAC77037,,,K-12,actP,,,,,,PHI:9227; PHI:9228,562,Escherichia coli,,FY26,avian colisepticemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,acetate/glycolate:cation symporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14123,PHI:9230,UniProt,P0AC98,GenBank,AAC73121,,,K-12,satP,,,,,,,562,Escherichia coli,,FY26,avian colisepticemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,succinate-acetate/proton symporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Acetate assimilation system encoded by acs-yjcH-actP operon was required for APEC-induced cytotoxicity to macrophages.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14124,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,,562,Escherichia coli,,FY26,avian colisepticemia,birds,8839,Anas platyrhynchos (related: mallard),HBK-Q-SPF,,,lung,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of actP/yjcH/acs genes attenuated APEC virulence and colonization capability in avian lungs in vivo for colibacillosis infection models.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14125,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,PHI:9228; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,birds,8839,Anas platyrhynchos (related: mallard),HBK-Q-SPF,,,lung,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of actP/yjcH/acs genes attenuated APEC virulence and colonization capability in avian lungs in vivo for colibacillosis infection models.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14126,PHI:9228,UniProt,P0AF54,GenBank,AAC77038,,,K-12,yjcH,,,,,,PHI:9227; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,birds,8839,Anas platyrhynchos (related: mallard),HBK-Q-SPF,,,lung,conserved inner membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of actP/yjcH/acs genes attenuated APEC virulence and colonization capability in avian lungs in vivo for colibacillosis infection models.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14127,PHI:9229,UniProt,P32705,GenBank,AAC77037,,,K-12,actP,,,,,,PHI:9227; PHI:9228,562,Escherichia coli,,FY26,avian colisepticemia,birds,8839,Anas platyrhynchos (related: mallard),HBK-Q-SPF,,,lung,acetate/glycolate:cation symporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of actP/yjcH/acs genes attenuated APEC virulence and colonization capability in avian lungs in vivo for colibacillosis infection models.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14128,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,,562,Escherichia coli,,FY26,avian colisepticemia,birds,8839,Anas platyrhynchos (related: mallard),HBK-Q-SPF,,,blood; liver; spleen; brain; kidney,acetyl-coenzyme A synthetase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,"Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in bacteria proliferation in the avian blood, spleen, liver, brain and kidney tissues in vivo.",X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14129,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,PHI:9228; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,birds,8839,Anas platyrhynchos (related: mallard),HBK-Q-SPF,,,blood; liver; spleen; brain; kidney,acetyl-coenzyme A synthetase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,"Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in bacteria proliferation in the avian blood, spleen, liver, brain and kidney tissues in vivo.",X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14130,PHI:9228,UniProt,P0AF54,GenBank,AAC77038,,,K-12,yjcH,,,,,,PHI:9227; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,birds,8839,Anas platyrhynchos (related: mallard),HBK-Q-SPF,,,blood; liver; spleen; brain; kidney,conserved inner membrane protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,"Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in bacteria proliferation in the avian blood, spleen, liver, brain and kidney tissues in vivo.",X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14131,PHI:9229,UniProt,P32705,GenBank,AAC77037,,,K-12,actP,,,,,,PHI:9227; PHI:9228,562,Escherichia coli,,FY26,avian colisepticemia,birds,8839,Anas platyrhynchos (related: mallard),HBK-Q-SPF,,,blood; liver; spleen; brain; kidney,acetate/glycolate:cation symporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,"Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in bacteria proliferation in the avian blood, spleen, liver, brain and kidney tissues in vivo.",X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14132,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),,,,lung,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of actP/yjcH/acs genes attenuated APEC virulence and colonization capability in avian lungs in vivo for colibacillosis infection models.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14133,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,PHI:9228; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),,,,lung,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of actP/yjcH/acs genes attenuated APEC virulence and colonization capability in avian lungs in vivo for colibacillosis infection models.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14134,PHI:9228,UniProt,P0AF54,GenBank,AAC77038,,,K-12,yjcH,,,,,,PHI:9227; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),,,,lung,conserved inner membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of actP/yjcH/acs genes attenuated APEC virulence and colonization capability in avian lungs in vivo for colibacillosis infection models.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14135,PHI:9229,UniProt,P32705,GenBank,AAC77037,,,K-12,actP,,,,,,PHI:9227; PHI:9228,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),,,,lung,acetate/glycolate:cation symporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of actP/yjcH/acs genes attenuated APEC virulence and colonization capability in avian lungs in vivo for colibacillosis infection models.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14136,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),,,,blood,acetyl-coenzyme A synthetase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in bacteria proliferation in the avian blood in vivo.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14137,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,PHI:9228; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),,,,blood,acetyl-coenzyme A synthetase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in bacteria proliferation in the avian blood in vivo.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14138,PHI:9228,UniProt,P0AF54,GenBank,AAC77038,,,K-12,yjcH,,,,,,PHI:9227; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),,,,blood,conserved inner membrane protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in bacteria proliferation in the avian blood in vivo.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14139,PHI:9229,UniProt,P32705,GenBank,AAC77037,,,K-12,actP,,,,,,PHI:9227; PHI:9228,562,Escherichia coli,,FY26,avian colisepticemia,birds,9031,Gallus gallus (related: chicken),,,,blood,acetate/glycolate:cation symporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in bacteria proliferation in the avian blood in vivo.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14140,PHI:9227,UniProt,P27550,GenBank,AAC43163,,,K-12,acs,,,,,,PHI:9228; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,rodents,10090,Mus musculus (related: house mouse),,,,,acetyl-coenzyme A synthetase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in murine sepsis model.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14141,PHI:9228,UniProt,P0AF54,GenBank,AAC77038,,,K-12,yjcH,,,,,,PHI:9227; PHI:9229,562,Escherichia coli,,FY26,avian colisepticemia,rodents,10090,Mus musculus (related: house mouse),,,,,conserved inner membrane protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in murine sepsis model.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14142,PHI:9229,UniProt,P32705,GenBank,AAC77037,,,K-12,actP,,,,,,PHI:9227; PHI:9228,562,Escherichia coli,,FY26,avian colisepticemia,rodents,10090,Mus musculus (related: house mouse),,,,,acetate/glycolate:cation symporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31046828,PubMed,10.1186/s13567-019-0650-2,Vet Res. 2019 May 2;50(1):31,daijianjun@njau.edu.cn,Deletion of acs-yjcH-actP operon had no effect on the APEC virulence in murine sepsis model.,X Zhuge 2019,2019,4 genes,Zhuge-2019-Acetate metabolic requirement of av,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14143,PHI:9231,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,invasion regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31017982,PubMed,10.1371/journal.ppat.1007700,PLoS Pathog. 2019 Apr 24;15(4):e1007700,altier@cornell.edu,"Changing a single base pair within first stem-loop (SL1) of hilD, predicted to augment its stability, eliminated expression of invasion genes and significantly reduced Salmonella virulence in mice.",C C Hung 2019,2019,1 gene,Hung-2019-Salmonella invasion is controlled th,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14144,PHI:9231,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,A25G/T53C,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,invasion regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31017982,PubMed,10.1371/journal.ppat.1007700,PLoS Pathog. 2019 Apr 24;15(4):e1007700,altier@cornell.edu,"Changing a single base pair within first stem-loop (SL1) of hilD, predicted to augment its stability, eliminated expression of invasion genes and significantly reduced Salmonella virulence in mice.",C C Hung 2019,2019,1 gene,Hung-2019-Salmonella invasion is controlled th,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14145,PHI:9231,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,A57T/G58C/T59C,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,invasion regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31017982,PubMed,10.1371/journal.ppat.1007700,PLoS Pathog. 2019 Apr 24;15(4):e1007700,altier@cornell.edu,"Changing a single base pair within first stem-loop (SL1) of hilD, predicted to augment its stability, eliminated expression of invasion genes and significantly reduced Salmonella virulence in mice.",C C Hung 2019,2019,1 gene,Hung-2019-Salmonella invasion is controlled th,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14146,PHI:9231,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,A25G,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,invasion regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31017982,PubMed,10.1371/journal.ppat.1007700,PLoS Pathog. 2019 Apr 24;15(4):e1007700,altier@cornell.edu,"Changing a single base pair within first stem-loop (SL1) of hilD, predicted to augment its stability, eliminated expression of invasion genes and significantly reduced Salmonella virulence in mice.",C C Hung 2019,2019,1 gene,Hung-2019-Salmonella invasion is controlled th,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14147,PHI:9231,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,T53C,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,invasion regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31017982,PubMed,10.1371/journal.ppat.1007700,PLoS Pathog. 2019 Apr 24;15(4):e1007700,altier@cornell.edu,"Changing a single base pair within first stem-loop (SL1) of hilD, predicted to augment its stability, eliminated expression of invasion genes and significantly reduced Salmonella virulence in mice.",C C Hung 2019,2019,1 gene,Hung-2019-Salmonella invasion is controlled th,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14148,PHI:9231,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,A25G/T53C,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c (Slc11a1<-/->),,,spleen; liver,invasion regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31017982,PubMed,10.1371/journal.ppat.1007700,PLoS Pathog. 2019 Apr 24;15(4):e1007700,altier@cornell.edu,"Changing a single base pair within first stem-loop (SL1) of hilD, predicted to augment its stability, eliminated expression of invasion genes and significantly reduced Salmonella virulence in mice.",C C Hung 2019,2019,1 gene,Hung-2019-Salmonella invasion is controlled th,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14149,PHI:9231,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,A25G,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c (Slc11a1<-/->),,,spleen; liver,invasion regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31017982,PubMed,10.1371/journal.ppat.1007700,PLoS Pathog. 2019 Apr 24;15(4):e1007700,altier@cornell.edu,"Changing a single base pair within first stem-loop (SL1) of hilD, predicted to augment its stability, eliminated expression of invasion genes and significantly reduced Salmonella virulence in mice.",C C Hung 2019,2019,1 gene,Hung-2019-Salmonella invasion is controlled th,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14150,PHI:9231,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,T53C,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c (Slc11a1<-/->),,,spleen; liver,invasion regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31017982,PubMed,10.1371/journal.ppat.1007700,PLoS Pathog. 2019 Apr 24;15(4):e1007700,altier@cornell.edu,"Changing a single base pair within first stem-loop (SL1) of hilD, predicted to augment its stability, eliminated expression of invasion genes and significantly reduced Salmonella virulence in mice.",C C Hung 2019,2019,1 gene,Hung-2019-Salmonella invasion is controlled th,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14151,PHI:9232,UniProt,A0A0H2ZDM9,GenBank,ABJ12377,,,UCBPP-PA14,hepP (PA14_23430),,PA14/MrT7::PA14_23430-480 Gmr (MAR2xT7 transposon is inserted at nucleotide 480),,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,spleen; liver; blood; skin,heparinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29061710,PubMed,10.1128/IAI.00755-17,Infect Immun. 2017 Dec 19;86(1),abdul.hamood@ttuhsc.edu,"Despite the inability of PA14::hepP to spread systemically, PA14::hepP formed perivascular cuffs around the blood vessels within the skin of the thermally injured/infected mice.",N Dzvova 2017,2017,3 genes,Dzvova-2017-Heparinase Is Essential for Pseudo,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14152,PHI:9232,UniProt,A0A0H2ZDM9,GenBank,ABJ12377,,,UCBPP-PA14,hepP (PA14_23430),,PA14/MrT7::PA14_23430-480 Gmr (MAR2xT7 transposon is inserted at nucleotide 480),,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,skin,heparinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29061710,PubMed,10.1128/IAI.00755-17,Infect Immun. 2017 Dec 19;86(1),abdul.hamood@ttuhsc.edu,PA14::hepP was not defective in its growth within the injured skin but was defective in its systemic spread within the bodies of the thermally injured/infected mice.,N Dzvova 2017,2017,3 genes,Dzvova-2017-Heparinase Is Essential for Pseudo,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14153,PHI:9233,UniProt,A0A0H2ZIL1,GenBank,ABJ14383,,,UCBPP-PA14,PA14_66100,,PA14/MrT7::PA14_66100-136 Gmr (MAR2xT7 transposon is inserted at nucleotide 136),,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,spleen; liver,hypothetical membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29061710,PubMed,10.1128/IAI.00755-17,Infect Immun. 2017 Dec 19;86(1),abdul.hamood@ttuhsc.edu,"The number of CFU obtained from the livers and spleens of injured mice infected with mutants, PA14::66100 and PA14::wzz paralleled with mice infected with PA14.",N Dzvova 2017,2017,3 genes,Dzvova-2017-Heparinase Is Essential for Pseudo,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14154,PHI:9234,UniProt,A0A0H2ZDL1,GenBank,ABJ12384,,,UCBPP-PA14,PA14_23360 (wzz),,PA14/MrT7::PA14_23360-113 Gmr (MAR2xT7 transposon is inserted at nucleotide 113),,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,spleen; liver,hypothetical membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29061710,PubMed,10.1128/IAI.00755-17,Infect Immun. 2017 Dec 19;86(1),abdul.hamood@ttuhsc.edu,"The number of CFU obtained from the livers and spleens of injured mice infected with mutants, PA14::66100 and PA14::wzz paralleled with mice infected with PA14.",N Dzvova 2017,2017,3 genes,Dzvova-2017-Heparinase Is Essential for Pseudo,BATCH_093B,2019-06-01,MC,,,,,,,,,,,,,
,,Record 14155,PHI:9235,UniProt,A0A0U5FK20,GenBank,CEG18794,,,,phoP,,,,,,,346,Xanthomonas citri,,subsp. citri strain XHG3,canker (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Xinhuigan,,,leaf,virulence transcriptional regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,YVS,31064142,PubMed,10.3390/genes10050340,Genes (Basel). 2019 May 6;10(5). pii: E340,qgliu@scau.edu.cn,Mutation of phoP reduced motility and biofilm formation in X. citri subsp. citri.,C Wei 2019,2019,1 gene,Wei-2019-Global Regulator PhoP is Necessary fo,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14156,PHI:9235,UniProt,A0A0U5FK20,GenBank,CEG18794,,,,phoP,,,,,,,346,Xanthomonas citri,,subsp. citri strain XHG3,canker (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Orah,,,leaf,virulence transcriptional regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,YVS,31064142,PubMed,10.3390/genes10050340,Genes (Basel). 2019 May 6;10(5). pii: E340,qgliu@scau.edu.cn,Mutation of phoP reduced motility and biofilm formation in X. citri subsp. citri.,C Wei 2019,2019,1 gene,Wei-2019-Global Regulator PhoP is Necessary fo,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14157,PHI:9236,UniProt,Q18CB9,GenBank,CAJ66847,,,630,CdPpiB (CD630_00330),,,,lrp; fliC; cysK,UniProt: A0A069AM73; GenBank: KPI47362; UniProt: Q9RQU7; GenBank: AF065259_1; UniProt: Q186F,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),NIH 3T3 cell line,,,fibroblast cell line,cyclophilin-type peptidyl-prolyl-cis/trans-isomerase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31024308,PubMed,10.3389/fphar.2019.00340,Front Pharmacol. 2019 Apr 5;10:340,unal@tau.edu.tr,Deletion of ppiB increased toxin production and cytotoxic activity.,C M Unal 2019,2019,1 gene,Unal-2019-Pleiotropic Clostridioides difficile,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14158,PHI:9237,UniProt,A0A0H2ZHS2,GenBank,ABJ14014,,,UCBPP-PA14,mgtC,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,alveolar macrophage,putative magnesium transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31001488,PubMed,10.3389/fcimb.2019.00084,Front Cell Infect Microbiol. 2019 Apr 2;9:84,anne.blanc-potard@univ-montp2.fr,Survival defect of P. aeruginosa mgtC mutant was not linked to increased production of Psl or alginate.,M Moussouni 2019,2019,4 genes,Moussouni-2019-Activity of a Synthetic Peptide,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14159,PHI:9237,UniProt,A0A0H2ZHS2,GenBank,ABJ14014,,,UCBPP-PA14,mgtC,,,,,,PHI:9238,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,alveolar macrophage,putative magnesium transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31001488,PubMed,10.3389/fcimb.2019.00084,Front Cell Infect Microbiol. 2019 Apr 2;9:84,anne.blanc-potard@univ-montp2.fr,Survival defect of P. aeruginosa mgtC mutant was not linked to increased production of Psl or alginate.,M Moussouni 2019,2019,4 genes,Moussouni-2019-Activity of a Synthetic Peptide,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14160,PHI:9238,UniProt,Q9I1N5,GenBank,AE004649_13,,,PAO1,pslD,,,,,,PHI:9237,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,alveolar macrophage,biofilm formation protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31001488,PubMed,10.3389/fcimb.2019.00084,Front Cell Infect Microbiol. 2019 Apr 2;9:84,anne.blanc-potard@univ-montp2.fr,Survival defect of P. aeruginosa mgtC mutant was not linked to increased production of Psl or alginate.,M Moussouni 2019,2019,4 genes,Moussouni-2019-Activity of a Synthetic Peptide,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14161,PHI:9237,UniProt,A0A0H2ZHS2,GenBank,ABJ14014,,,UCBPP-PA14,mgtC,,,,,,PHI:9239,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,alveolar macrophage,putative magnesium transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31001488,PubMed,10.3389/fcimb.2019.00084,Front Cell Infect Microbiol. 2019 Apr 2;9:84,anne.blanc-potard@univ-montp2.fr,Survival defect of P. aeruginosa mgtC mutant was not linked to increased production of Psl or alginate.,M Moussouni 2019,2019,4 genes,Moussouni-2019-Activity of a Synthetic Peptide,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14162,PHI:9239,UniProt,Q52463,GenBank,AE004774_7,,,PAO1,alg8,,,,,,PHI:9237,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,alveolar macrophage,alginate biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31001488,PubMed,10.3389/fcimb.2019.00084,Front Cell Infect Microbiol. 2019 Apr 2;9:84,anne.blanc-potard@univ-montp2.fr,Survival defect of P. aeruginosa mgtC mutant was not linked to increased production of Psl or alginate.,M Moussouni 2019,2019,4 genes,Moussouni-2019-Activity of a Synthetic Peptide,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14163,PHI:9240,,no data found,,,,,,mgtR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,alveolar macrophage,regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,other evidence: recombinant protein,,,YVS,31001488,PubMed,10.3389/fcimb.2019.00084,Front Cell Infect Microbiol. 2019 Apr 2;9:84,anne.blanc-potard@univ-montp2.fr,"Exogenously added synthetic MgtR peptide lowered the intramacrophage survival of wild-type P. aeruginosa PAO1, thus mimicking the phenotype of an mgtC mutant as well as the effect of endogenously produced MgtR peptide.",M Moussouni 2019,2019,4 genes,Moussouni-2019-Activity of a Synthetic Peptide,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14164,PHI:9241,UniProt,I1RDQ0,GenBank,CEF73950,,,PH-1,Fghyd2 (FGSG_01764),chromosome 1,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,reduced virulence,,,yes,,,wild type,wild type,reduced,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14165,PHI:9242,UniProt,I1RXJ5,GenBank,CEF84703,,,PH-1,Fghyd3 (FGSG_09066),chromosome 4,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,reduced virulence,,,yes,,,wild type,wild type,wild type,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14166,PHI:9243,UniProt,I1RJE5,GenBank,CEF78867,,,PH-1,Fghyd4 (FGSG_03960),chromosome 2,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,hydrophobin,,,,reduced virulence,,,no,,,wild type,wild type,wild type,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14167,PHI:9241,UniProt,I1RDQ0,GenBank,CEF73950,,,PH-1,Fghyd2 (FGSG_01764),chromosome 1,,,,,PHI:9242; PHI:9243,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,reduced virulence,,,yes,,,wild type,wild type,reduced,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14168,PHI:9242,UniProt,I1RXJ5,GenBank,CEF84703,,,PH-1,Fghyd3 (FGSG_09066),chromosome 4,,,,,PHI:9241; PHI:9243,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,reduced virulence,,,yes,,,wild type,wild type,reduced,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14169,PHI:9243,UniProt,I1RJE5,GenBank,CEF78867,,,PH-1,Fghyd4 (FGSG_03960),chromosome 2,,,,,PHI:9241; PHI:9242,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,hydrophobin,,,,reduced virulence,,,yes,,,wild type,wild type,reduced,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14170,PHI:9244,UniProt,I1RDP9,GenBank,CEF73949,,,PH-1,Fghyd1 (FGSG_01763),chromosome 1,,,,,PHI:9241; PHI:9242,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,reduced virulence,,,yes,,,wild type,wild type,reduced,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14171,PHI:9241,UniProt,I1RDQ0,GenBank,CEF73950,,,PH-1,Fghyd2 (FGSG_01764),chromosome 1,,,,,PHI:9244; PHI:9242,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,reduced virulence,,,yes,,,wild type,wild type,reduced,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14172,PHI:9242,UniProt,I1RXJ5,GenBank,CEF84703,,,PH-1,Fghyd3 (FGSG_09066),chromosome 4,,,,,PHI:9244; PHI:9241,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,reduced virulence,,,yes,,,wild type,wild type,reduced,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14173,PHI:9241,UniProt,I1RDQ0,GenBank,CEF73950,,,PH-1,Fghyd2 (FGSG_01764),chromosome 1,,,,,PHI:9242; PHI:9245,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,reduced virulence,,,yes,,,wild type,wild type,reduced,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14174,PHI:9242,UniProt,I1RXJ5,GenBank,CEF84703,,,PH-1,Fghyd3 (FGSG_09066),chromosome 4,,,,,PHI:9241; PHI:9245,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,reduced virulence,,,yes,,,wild type,wild type,reduced,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14175,PHI:9245,UniProt,I1RDW3,GenBank,CEF74021,,,PH-1,Fghyd5 (FGSG_01831),chromosome 1,,,,,PHI:9241; PHI:9242,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,reduced virulence,,,yes,,,wild type,wild type,reduced,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14176,PHI:9244,UniProt,I1RDP9,GenBank,CEF73949,,,PH-1,Fghyd1 (FGSG_01763),chromosome 1,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,unaffected pathogenicity,,,no,,,wild type,wild type,wild type,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14177,PHI:9245,UniProt,I1RDW3,GenBank,CEF74021,,,PH-1,Fghyd5 (FGSG_01831),chromosome 1,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Nandu,,,spikelet,uncharacterised protein,,,,unaffected pathogenicity,,,no,,,wild type,wild type,wild type,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14178,PHI:9241,UniProt,I1RDQ0,GenBank,CEF73950,,,PH-1,Fghyd2 (FGSG_01764),chromosome 1,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Amaretto,,,spikelet,uncharacterised protein,,,,reduced virulence,,,,,,,,,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14179,PHI:9242,UniProt,I1RXJ5,GenBank,CEF84703,,,PH-1,Fghyd3 (FGSG_09066),chromosome 4,,,,,,5518,Fusarium graminearum,,8/1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Amaretto,,,spikelet,uncharacterised protein,,,,reduced virulence,,,,,,,,,,no,KCl; sorbitol; hydrogen peroxide (H2O2); calcofluor white; tebuconazole,KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; calcofluor white: CHEBI:50011; tebuconazole: CHEBI:81781,,,,,gene deletion; gene complementation,,,YVS,31031728,PubMed,10.3389/fmicb.2019.00751,Front Microbiol. 2019 Apr 12;10:751,analiliamartinezrocha@gmail.com,"Triple hydrophobin mutants were significantly more inhibited than wild-type by the treatment with a systemic triazole fungicide, while no defects at the cell wall level were observed.",A Quarantin 2019,2019,5 genes,Quarantin-2019-Different Hydrophobins of Fusar,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14180,PHI:9246,UniProt,Q8Z2C1,GenBank,AAO71335,,,Ty2,malS,,malS-5′UTR,,,,,28901,Salmonella enterica,90370,subsp. enterica serovar Typhi strain GIFU10007,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocytic leukemia cell line,regulatory non-coding RNA,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29306008,PubMed,10.1016/j.micpath.2017.12.072,Microb Pathog. 2018 Feb;115:321-331,huxinx@ujs.edu.cn,Overexpression of the malS-5′UTR decreased S. Typhi survival within macrophages.,F Dong 2018,2018,1 gene,Dong-2018-The malS-5'UTR weakens the ability o,BATCH_093C,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14181,PHI:9247,UniProt,A0QLI5,GenBank,ABK66967,,,104,MAV_4644,,MAV_4644:Tn,,,,,1764,Mycobacterium avium,439334,subsp. hominissuis strain 104,respiratory disease,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,putative pore-forming function and ADP-ribosyltransferase activity,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31117286,PubMed,10.3390/microorganisms7050144,Microorganisms. 2019 May 21;7(5),luiz.bermudez@oregonstate.edu,Knocking-down the cathepsin Z in human macrophages rescued the attenuated phenotype of MAV_4644:Tn clone.,M S Lewis 2019,2019,1 gene,Lewis-2019-MAV_4644 Interaction with the Host,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14182,PHI:9247,UniProt,A0QLI5,GenBank,ABK66967,,,104,MAV_4644,,MAV_4644:Tn,,,,,1764,Mycobacterium avium,439334,subsp. hominissuis strain 104,respiratory disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative pore-forming function and ADP-ribosyltransferase activity,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31117286,PubMed,10.3390/microorganisms7050144,Microorganisms. 2019 May 21;7(5),luiz.bermudez@oregonstate.edu,Knocking-down the cathepsin Z in human macrophages rescued the attenuated phenotype of MAV_4644:Tn clone.,M S Lewis 2019,2019,1 gene,Lewis-2019-MAV_4644 Interaction with the Host,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14183,PHI:9248,UniProt,Q87KC3,GenBank,BAC61317,,,O3:K6,VpDsbA1 (VP3054),chromosome 1,,,,,,670,Vibrio parahaemolyticus,,HZ,gastrointestinal disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,,thiol:disulfide interchange protein,,,,unaffected pathogenicity,,,,,,,,,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,31156607,PubMed,10.3389/fmicb.2019.01103,Front Microbiol. 2019 May 16;10:1103,yangmh@zafu.edu.cn,"V. parahaemolyticus lacking dsbA showed reduced attachment to Caco-2 cells, decreased b-hemolytic activity, and less toxicity to both zebraffish and HeLa cells.",C Q Wu 2019,2019,2 genes,Wu-2019-Two DsbA Proteins Are Important for Vi,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14184,PHI:9249,UniProt,Q87GP4,GenBank,BAC62614,,,O3:K6,VpDsbA2 (VPA1271),chromosome 2,,,,,,670,Vibrio parahaemolyticus,,HZ,gastrointestinal disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,,thiol:disulfide interchange protein,,,,unaffected pathogenicity,,,,,,,,,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,31156607,PubMed,10.3389/fmicb.2019.01103,Front Microbiol. 2019 May 16;10:1103,yangmh@zafu.edu.cn,"V. parahaemolyticus lacking dsbA showed reduced attachment to Caco-2 cells, decreased b-hemolytic activity, and less toxicity to both zebraffish and HeLa cells.",C Q Wu 2019,2019,2 genes,Wu-2019-Two DsbA Proteins Are Important for Vi,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14185,PHI:9248,UniProt,Q87KC3,GenBank,BAC61317,,,O3:K6,VpDsbA1 (VP3054),chromosome 1,,,,,PHI:9249,670,Vibrio parahaemolyticus,,HZ,gastrointestinal disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,,thiol:disulfide interchange protein,,,,reduced virulence,,,,,,,,,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,31156607,PubMed,10.3389/fmicb.2019.01103,Front Microbiol. 2019 May 16;10:1103,yangmh@zafu.edu.cn,"V. parahaemolyticus lacking dsbA showed reduced attachment to Caco-2 cells, decreased b-hemolytic activity, and less toxicity to both zebraffish and HeLa cells.",C Q Wu 2019,2019,2 genes,Wu-2019-Two DsbA Proteins Are Important for Vi,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14186,PHI:9249,UniProt,Q87GP4,GenBank,BAC62614,,,O3:K6,VpDsbA2 (VPA1271),chromosome 2,,,,,PHI:9248,670,Vibrio parahaemolyticus,,HZ,gastrointestinal disease,bony fishes,7955,Danio rerio (related: zebrafish),,,,,thiol:disulfide interchange protein,,,,reduced virulence,,,,,,,,,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,31156607,PubMed,10.3389/fmicb.2019.01103,Front Microbiol. 2019 May 16;10:1103,yangmh@zafu.edu.cn,"V. parahaemolyticus lacking dsbA showed reduced attachment to Caco-2 cells, decreased b-hemolytic activity, and less toxicity to both zebraffish and HeLa cells.",C Q Wu 2019,2019,2 genes,Wu-2019-Two DsbA Proteins Are Important for Vi,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14187,PHI:9248,UniProt,Q87KC3,GenBank,BAC61317,,,O3:K6,VpDsbA1 (VP3054),chromosome 1,,,,,,670,Vibrio parahaemolyticus,,HZ,gastrointestinal disease,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,thiol:disulfide interchange protein,,,,reduced virulence,,,,,,,,,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,31156607,PubMed,10.3389/fmicb.2019.01103,Front Microbiol. 2019 May 16;10:1103,yangmh@zafu.edu.cn,"V. parahaemolyticus lacking dsbA showed reduced attachment to Caco-2 cells, decreased b-hemolytic activity, and less toxicity to both zebraffish and HeLa cells.",C Q Wu 2019,2019,2 genes,Wu-2019-Two DsbA Proteins Are Important for Vi,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14188,PHI:9249,UniProt,Q87GP4,GenBank,BAC62614,,,O3:K6,VpDsbA2 (VPA1271),chromosome 2,,,,,,670,Vibrio parahaemolyticus,,HZ,gastrointestinal disease,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,thiol:disulfide interchange protein,,,,reduced virulence,,,,,,,,,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,31156607,PubMed,10.3389/fmicb.2019.01103,Front Microbiol. 2019 May 16;10:1103,yangmh@zafu.edu.cn,"V. parahaemolyticus lacking dsbA showed reduced attachment to Caco-2 cells, decreased b-hemolytic activity, and less toxicity to both zebraffish and HeLa cells.",C Q Wu 2019,2019,2 genes,Wu-2019-Two DsbA Proteins Are Important for Vi,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14189,PHI:9248,UniProt,Q87KC3,GenBank,BAC61317,,,O3:K6,VpDsbA1 (VP3054),chromosome 1,,,,,PHI:9249,670,Vibrio parahaemolyticus,,HZ,gastrointestinal disease,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,thiol:disulfide interchange protein,,,,reduced virulence,,,,,,,,,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,31156607,PubMed,10.3389/fmicb.2019.01103,Front Microbiol. 2019 May 16;10:1103,yangmh@zafu.edu.cn,"V. parahaemolyticus lacking dsbA showed reduced attachment to Caco-2 cells, decreased b-hemolytic activity, and less toxicity to both zebraffish and HeLa cells.",C Q Wu 2019,2019,2 genes,Wu-2019-Two DsbA Proteins Are Important for Vi,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14190,PHI:9249,UniProt,Q87GP4,GenBank,BAC62614,,,O3:K6,VpDsbA2 (VPA1271),chromosome 2,,,,,PHI:9248,670,Vibrio parahaemolyticus,,HZ,gastrointestinal disease,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,thiol:disulfide interchange protein,,,,reduced virulence,,,,,,,,,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,31156607,PubMed,10.3389/fmicb.2019.01103,Front Microbiol. 2019 May 16;10:1103,yangmh@zafu.edu.cn,"V. parahaemolyticus lacking dsbA showed reduced attachment to Caco-2 cells, decreased b-hemolytic activity, and less toxicity to both zebraffish and HeLa cells.",C Q Wu 2019,2019,2 genes,Wu-2019-Two DsbA Proteins Are Important for Vi,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14191,PHI:9248,UniProt,Q87KC3,GenBank,BAC61317,,,O3:K6,VpDsbA1 (VP3054),chromosome 1,,,,,PHI:9249,670,Vibrio parahaemolyticus,,HZ,gastrointestinal disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,thiol:disulfide interchange protein,,,,reduced virulence,,,,,,,,,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,31156607,PubMed,10.3389/fmicb.2019.01103,Front Microbiol. 2019 May 16;10:1103,yangmh@zafu.edu.cn,"V. parahaemolyticus lacking dsbA showed reduced attachment to Caco-2 cells, decreased b-hemolytic activity, and less toxicity to both zebraffish and HeLa cells.",C Q Wu 2019,2019,2 genes,Wu-2019-Two DsbA Proteins Are Important for Vi,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14192,PHI:9249,UniProt,Q87GP4,GenBank,BAC62614,,,O3:K6,VpDsbA2 (VPA1271),chromosome 2,,,,,PHI:9248,670,Vibrio parahaemolyticus,,HZ,gastrointestinal disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,thiol:disulfide interchange protein,,,,reduced virulence,,,,,,,,,,no,cadmium,cadmium: CHEBI:37249,,,,,gene deletion: full; gene complementation,,,YVS,31156607,PubMed,10.3389/fmicb.2019.01103,Front Microbiol. 2019 May 16;10:1103,yangmh@zafu.edu.cn,"V. parahaemolyticus lacking dsbA showed reduced attachment to Caco-2 cells, decreased b-hemolytic activity, and less toxicity to both zebraffish and HeLa cells.",C Q Wu 2019,2019,2 genes,Wu-2019-Two DsbA Proteins Are Important for Vi,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14193,PHI:9250,UniProt,A0A0L0VJ47,GenBank,PSTG_07828,,,,PsRPs26,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici strain CYR31,yellow rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,40S ribosomal subunit structural protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31134016,PubMed,10.3389/fmicb.2019.00968,Front Microbiol. 2019 May 10;10:968,kangzs@nwsuaf.edu.cn,Knockdown of PsRPs26 by a host-induced gene silencing system inhibited growth and limited urediospore production in Pst.,B Wang 2019,2019,1 gene,"Wang-2019-PsRPs26, a 40S Ribosomal Protein Sub",BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14194,PHI:9251,UniProt,Q7VWL6,GenBank,CAE42471,,,Tohama I,hfq,,,,,,,520,Bordetella pertussis,257313,Tohama I,pertussis,primates,9606,Homo sapiens (related: human),,,,serum,putative RNA-binding regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31238496,PubMed,10.3390/ijms20123073,Int J Mol Sci. 2019 Jun 24;20(12),vecerek@biomed.cas.cz,ΔHfq strain displayed strongly impaired secretion of substrates of Type III secretion system (T3SS) and substantially reduced resistance to serum killing.,A Dienstbier 2019,2019,1 gene,Dienstbier-2019-Comparative Integrated Omics A,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14195,PHI:9252,UniProt,Q7BU69,GenBank,BAA05480,,,YSH6000,virA,,,,,,,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),Caco-2/TC7 cell line,,,colonic epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31209035,PubMed,10.1073/pnas.1902922116,Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13582-13591,nathalie.sauvonnet@pasteur.fr,IpaJ and VirA induced large-scale impairment of host protein secretion and block the recycling of surface receptors.,M L Ferrari 2019,2019,2 genes,Ferrari-2019-Shigella promotes major alteratio,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14196,PHI:9253,UniProt,Q54150,GenBank,AAA84386,,,M9OT-W,ipaJ,,,,,,,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),Caco-2/TC7 cell line,,,colonic epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31209035,PubMed,10.1073/pnas.1902922116,Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13582-13591,nathalie.sauvonnet@pasteur.fr,IpaJ and VirA induced large-scale impairment of host protein secretion and block the recycling of surface receptors.,M L Ferrari 2019,2019,2 genes,Ferrari-2019-Shigella promotes major alteratio,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14197,PHI:9252,UniProt,Q7BU69,GenBank,BAA05480,,,YSH6000,virA,,,,,,PHI:9253,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),Caco-2/TC7 cell line,,,colonic epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31209035,PubMed,10.1073/pnas.1902922116,Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13582-13591,nathalie.sauvonnet@pasteur.fr,IpaJ and VirA induced large-scale impairment of host protein secretion and block the recycling of surface receptors.,M L Ferrari 2019,2019,2 genes,Ferrari-2019-Shigella promotes major alteratio,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14198,PHI:9253,UniProt,Q54150,GenBank,AAA84386,,,M9OT-W,ipaJ,,,,,,PHI:9252,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),Caco-2/TC7 cell line,,,colonic epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31209035,PubMed,10.1073/pnas.1902922116,Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13582-13591,nathalie.sauvonnet@pasteur.fr,IpaJ and VirA induced large-scale impairment of host protein secretion and block the recycling of surface receptors.,M L Ferrari 2019,2019,2 genes,Ferrari-2019-Shigella promotes major alteratio,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14199,PHI:9254,UniProt,T0KBL8,GenBank,EQB52767,,,Cg-14,CgGCS,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,fruit rot,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,glucosylceramide synthase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31164871,PubMed,10.3389/fmicb.2019.01016,Front Microbiol. 2019 May 21;10:1016,yiganjun@vip.163.com,Disruption of CgGCS resulted in a severe reduction of mycelial growth and defects in conidiogenesis.,Y Huang 2019,2019,1 gene,"Huang-2019-CgGCS, Encoding a Glucosylceramide",BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14200,PHI:9254,UniProt,T0KBL8,GenBank,EQB52767,,,Cg-14,CgGCS,,,,,,,474922,Colletotrichum gloeosporioides,1237896,Cg-14,fruit rot,eudicots,29780,Mangifera indica (related: mango),,,,fruit,glucosylceramide synthase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31164871,PubMed,10.3389/fmicb.2019.01016,Front Microbiol. 2019 May 21;10:1016,yiganjun@vip.163.com,Disruption of CgGCS resulted in a severe reduction of mycelial growth and defects in conidiogenesis.,Y Huang 2019,2019,1 gene,"Huang-2019-CgGCS, Encoding a Glucosylceramide",BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14201,PHI:9255,UniProt,Q4W9Q8,GenBank,EAL84555,,,Af293,msbA (AFUA_4G04070),chromosome 4,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,signalling mucin and core sensor,,,,increased virulence (hypervirulence),,,,,,reduced,,reduced,,no,Congo red; calcofluor white; nikkomycin Z; NaCl; voriconazole; itraconazole; caspofungin,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; nikkomycin Z: CHEBI:623918; NaCl: CHEBI:26710; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31217305,PubMed,10.1128/mSphere.00350-19,mSphere. 2019 Jun 19;4(3),fredsori@icb.ufmg.br,"The ΔmsbA mutant strain induced less inflammation with diminished cell influx into the lungs and lower cytokine production, culminating in increased lethality rate.",I L D S Gurgel 2019,2019,1 gene,Gurgel-2019-The Aspergillus fumigatus Mucin Ms,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14202,PHI:9255,UniProt,Q4W9Q8,GenBank,EAL84555,,,Af293,msbA (AFUA_4G04070),chromosome 4,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive aspergillosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,signalling mucin and core sensor,,,,increased virulence (hypervirulence),,,,,,reduced,,reduced,,no,Congo red; calcofluor white; nikkomycin Z; NaCl; voriconazole; itraconazole; caspofungin,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; nikkomycin Z: CHEBI:623918; NaCl: CHEBI:26710; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31217305,PubMed,10.1128/mSphere.00350-19,mSphere. 2019 Jun 19;4(3),fredsori@icb.ufmg.br,"The ΔmsbA mutant strain induced less inflammation with diminished cell influx into the lungs and lower cytokine production, culminating in increased lethality rate.",I L D S Gurgel 2019,2019,1 gene,Gurgel-2019-The Aspergillus fumigatus Mucin Ms,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14203,PHI:9256,UniProt,P37194,GenBank,AAA60370,,,K-12,slp,,,,,,,562,Escherichia coli,,serotype O157:H7 strain EDL932,urinary tract infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelium,carbon starvation-inducible lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31188867,PubMed,10.1371/journal.pone.0216791,PLoS One. 2019 Jun 12;14(6):e0216791,skariyawasam@ufl.edu,"Disruption of Slp expression in E. coli O157:H7, produced a significant adherence deficiency to Caco-2 cells at early time points associated with initial adherence.",C Fedorchuk 2019,2019,1 gene,Fedorchuk-2019-The Escherichia coli O157_H7 ca,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14204,PHI:9257,UniProt,Q5A9D6,GenBank,AOW30904,,,SC5314,CaGPI15,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),MH-S cell line,,,alveolar macrophage cell line,phosphatidylinositol N-acetylglucosaminyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,ketoconazole,ketoconazole: CHEBI:48336,,,,,gene mutation; gene complementation,,,YVS,31186458,PubMed,10.1038/s41598-019-44919-4,Sci Rep. 2019 Jun 11;9(1):8508,sskomath@mail.jnu.ac.in,CaGPI15 mutant was susceptible to killing by macrophages and epithelial cells and had reduced ability to damage either of these cell lines relative to the wild type strain.,P Jain 2019,2019,1 gene,Jain-2019-Modulation of azole sensitivity and,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14205,PHI:9257,UniProt,Q5A9D6,GenBank,AOW30904,,,SC5314,CaGPI15,chromosome R,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),LA-4 cell line,,,epithelial cell,phosphatidylinositol N-acetylglucosaminyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,ketoconazole,ketoconazole: CHEBI:48336,,,,,gene mutation; gene complementation,,,YVS,31186458,PubMed,10.1038/s41598-019-44919-4,Sci Rep. 2019 Jun 11;9(1):8508,sskomath@mail.jnu.ac.in,CaGPI15 mutant was susceptible to killing by macrophages and epithelial cells and had reduced ability to damage either of these cell lines relative to the wild type strain.,P Jain 2019,2019,1 gene,Jain-2019-Modulation of azole sensitivity and,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14206,PHI:9258,UniProt,J9VS56,GenBank,AFR95419,,,H99,Annexin C1 (CNAG_02415),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,annexin,,,,unaffected pathogenicity,,,,,,,,,,no,"FK506; 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA); NaCl; calcofluor white; Congo red; caffeine; NiSO4; ZnSO4; H2O2; NaNO2","FK506: CHEBI:61049; 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA): CHEBI:60888; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; caffeine: CHEBI:27732; NiSO4: CHEBI:53001; ZnSO4: CHEBI:35176; H2O2: CHEBI:16240; NaNO2: CHEBI:78870",,,,,gene mutation,,,YVS,31140968,PubMed,10.1099/mic.0.000815,Microbiology. 2019 May 29,c.coelho@exeter.ac.uk,The only alteration observed in strains deleted for AnnexinC1 was a small increase in the titan cells' formation in vitro.,M Maryam 2019,2019,1 gene,Maryam-2019-The enigmatic role of fungal annex,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14207,PHI:9258,UniProt,J9VS56,GenBank,AFR95419,,,H99,Annexin C1 (CNAG_02415),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,alveolar macrophage,annexin,,,,unaffected pathogenicity,,,,,,,,,,no,"FK506; 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA); NaCl; calcofluor white; Congo red; caffeine; NiSO4; ZnSO4; H2O2; NaNO2","FK506: CHEBI:61049; 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA): CHEBI:60888; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; caffeine: CHEBI:27732; NiSO4: CHEBI:53001; ZnSO4: CHEBI:35176; H2O2: CHEBI:16240; NaNO2: CHEBI:78870",,,,,gene mutation,,,YVS,31140968,PubMed,10.1099/mic.0.000815,Microbiology. 2019 May 29,c.coelho@exeter.ac.uk,The only alteration observed in strains deleted for AnnexinC1 was a small increase in the titan cells' formation in vitro.,M Maryam 2019,2019,1 gene,Maryam-2019-The enigmatic role of fungal annex,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14208,PHI:9258,UniProt,J9VS56,GenBank,AFR95419,,,H99,Annexin C1 (CNAG_02415),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BV-2 cell line,,,microglial cell line,annexin,,,,unaffected pathogenicity,,,,,,,,,,no,"FK506; 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA); NaCl; calcofluor white; Congo red; caffeine; NiSO4; ZnSO4; H2O2; NaNO2","FK506: CHEBI:61049; 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA): CHEBI:60888; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; caffeine: CHEBI:27732; NiSO4: CHEBI:53001; ZnSO4: CHEBI:35176; H2O2: CHEBI:16240; NaNO2: CHEBI:78870",,,,,gene mutation,,,YVS,31140968,PubMed,10.1099/mic.0.000815,Microbiology. 2019 May 29,c.coelho@exeter.ac.uk,The only alteration observed in strains deleted for AnnexinC1 was a small increase in the titan cells' formation in vitro.,M Maryam 2019,2019,1 gene,Maryam-2019-The enigmatic role of fungal annex,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14209,PHI:9258,UniProt,J9VS56,GenBank,AFR95419,,,H99,Annexin C1 (CNAG_02415),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,annexin,,,,unaffected pathogenicity,,,,,,,,,,no,"FK506; 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA); NaCl; calcofluor white; Congo red; caffeine; NiSO4; ZnSO4; H2O2; NaNO2","FK506: CHEBI:61049; 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA): CHEBI:60888; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; caffeine: CHEBI:27732; NiSO4: CHEBI:53001; ZnSO4: CHEBI:35176; H2O2: CHEBI:16240; NaNO2: CHEBI:78870",,,,,gene mutation,,,YVS,31140968,PubMed,10.1099/mic.0.000815,Microbiology. 2019 May 29,c.coelho@exeter.ac.uk,The only alteration observed in strains deleted for AnnexinC1 was a small increase in the titan cells' formation in vitro.,M Maryam 2019,2019,1 gene,Maryam-2019-The enigmatic role of fungal annex,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14210,PHI:9258,UniProt,J9VS56,GenBank,AFR95419,,,H99,Annexin C1 (CNAG_02415),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,annexin,,,,unaffected pathogenicity,,,,,,,,,,no,"FK506; 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA); NaCl; calcofluor white; Congo red; caffeine; NiSO4; ZnSO4; H2O2; NaNO2","FK506: CHEBI:61049; 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA): CHEBI:60888; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; caffeine: CHEBI:27732; NiSO4: CHEBI:53001; ZnSO4: CHEBI:35176; H2O2: CHEBI:16240; NaNO2: CHEBI:78870",,,,,gene mutation,,,YVS,31140968,PubMed,10.1099/mic.0.000815,Microbiology. 2019 May 29,c.coelho@exeter.ac.uk,The only alteration observed in strains deleted for AnnexinC1 was a small increase in the titan cells' formation in vitro.,M Maryam 2019,2019,1 gene,Maryam-2019-The enigmatic role of fungal annex,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14211,PHI:9259,UniProt,G4N339,GenBank,EHA52595,,,70-15,MoBIR1 (MGG_04912),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,inhibitor of apoptosis protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,31175429,PubMed,10.1007/s00253-019-09931-8,Appl Microbiol Biotechnol. 2019 Jun 7,hfzhang@njau.edu.cn,"M. oryzae transformants overexpressing the MoBIR1 gene demonstrated increased growth rate and biomass, delayed mycelial aging, and enhanced resistance to hydrogen peroxide but reduced reactive oxygen species generation and virulence.",L Zhang 2019,2019,1 gene,Zhang-2019-The inhibitor of apoptosis protein,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14212,PHI:9259,UniProt,G4N339,GenBank,EHA52595,,,70-15,MoBIR1 (MGG_04912),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,inhibitor of apoptosis protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,31175429,PubMed,10.1007/s00253-019-09931-8,Appl Microbiol Biotechnol. 2019 Jun 7,hfzhang@njau.edu.cn,"M. oryzae transformants overexpressing the MoBIR1 gene demonstrated increased growth rate and biomass, delayed mycelial aging, and enhanced resistance to hydrogen peroxide but reduced reactive oxygen species generation and virulence.",L Zhang 2019,2019,1 gene,Zhang-2019-The inhibitor of apoptosis protein,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14213,PHI:9259,UniProt,G4N339,GenBank,EHA52595,,,70-15,MoBIR1 (MGG_04912),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,inhibitor of apoptosis protein,,,,reduced virulence,,,,,,,,increased,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31175429,PubMed,10.1007/s00253-019-09931-8,Appl Microbiol Biotechnol. 2019 Jun 7,hfzhang@njau.edu.cn,"M. oryzae transformants overexpressing the MoBIR1 gene demonstrated increased growth rate and biomass, delayed mycelial aging, and enhanced resistance to hydrogen peroxide but reduced reactive oxygen species generation and virulence.",L Zhang 2019,2019,1 gene,Zhang-2019-The inhibitor of apoptosis protein,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14214,PHI:9259,UniProt,G4N339,GenBank,EHA52595,,,70-15,MoBIR1 (MGG_04912),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,inhibitor of apoptosis protein,,,,reduced virulence,,,,,,,,increased,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31175429,PubMed,10.1007/s00253-019-09931-8,Appl Microbiol Biotechnol. 2019 Jun 7,hfzhang@njau.edu.cn,"M. oryzae transformants overexpressing the MoBIR1 gene demonstrated increased growth rate and biomass, delayed mycelial aging, and enhanced resistance to hydrogen peroxide but reduced reactive oxygen species generation and virulence.",L Zhang 2019,2019,1 gene,Zhang-2019-The inhibitor of apoptosis protein,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14215,PHI:9260,UniProt,W8U6D4,GenBank,AUS75592,,,MRSA107,purR,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,neutrophil,purine biosynthesis regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31217288,PubMed,10.1073/pnas.1904280116,Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13563-13572,victor.torres@nyulangone.org,Inactivating the purine biosynthesis regulator purR resulted in a strain that was acutely virulent in bloodstream infection models in mice and in ex vivo models using primary human neutrophils.,W E Sause 2019,2019,1 gene,Sause-2019-The purine biosynthesis regulator P,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14216,PHI:9260,UniProt,W8U6D4,GenBank,AUS75592,,,MRSA107,purR,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,kidney; liver; spleen; lung; heart; blood,purine biosynthesis regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31217288,PubMed,10.1073/pnas.1904280116,Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13563-13572,victor.torres@nyulangone.org,Inactivating the purine biosynthesis regulator purR resulted in a strain that was acutely virulent in bloodstream infection models in mice and in ex vivo models using primary human neutrophils.,W E Sause 2019,2019,1 gene,Sause-2019-The purine biosynthesis regulator P,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14217,PHI:9261,UniProt,Q4WHP3,GenBank,EAL87562,,,Af293,pakA (Afu2g04680),chromosome 2,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,high osmolarity glycerol mitogen activated protein kinase,,,,reduced virulence,,,,,,,,wild type,,no,Congo red; calcofluor white (CFW); echinocandin; caspofungin; sorbitol,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; echinocandin: CHEBI:57248; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911,,,,,gene deletion,,,YVS,31134001,PubMed,10.3389/fmicb.2019.00918,Front Microbiol. 2019 May 7;10:918,Ozgur.Bayram@mu.ie,"The ΔpakA strain was more sensitive to cell wall damaging agents as congo red, calcofluor white and caspofungin.",A O Manfiolli 2019,2019,1 gene,Manfiolli-2019-Aspergillus fumigatus High Osmo,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14218,PHI:9262,UniProt,P9WJD7,GenBank,CCP46438,,,H37Rv,espC (rv3615c),,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,ESX-1 secretion-associated protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,heterologous expression; altered gene expression / gene regulation: overexpression,,,YVS,31134163,PubMed,10.3389/fcimb.2019.00158,Front Cell Infect Microbiol. 2019 May 10;9:158,xuelianzhang@fudan.edu.cn,EspC overexpression enhanced the survival of M. smegmatis within macrophages and under stress conditions.,Q Guo 2019,2019,1 gene,Guo-2019-ESX Secretion-Associated Protein C Fr,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14219,PHI:9263,UniProt,Q03974,GenBank,AAA65534,,,RM7004,lic2A,,,,,,,727,Haemophilus influenzae,,NTHi 375,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,glycosyltransferase involved in LPS biosynthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31157175,PubMed,10.3389/fcimb.2019.00160,Front Cell Infect Microbiol. 2019 May 15;9:160,bakerley@umc.edu,The galE mutants exhibited restored virulence properties in a lic2A mutant background.,S M Wong 2019,2019,2 genes,Wong-2019-Suppression of Alternative Lipooligo,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14220,PHI:9264,UniProt,P24325,GenBank,CAA40568,,,RM.7004,galE,,,,,,,727,Haemophilus influenzae,,NTHi 375,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,UDP-glucose 4-epimerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31157175,PubMed,10.3389/fcimb.2019.00160,Front Cell Infect Microbiol. 2019 May 15;9:160,bakerley@umc.edu,The galE mutants exhibited restored virulence properties in a lic2A mutant background.,S M Wong 2019,2019,2 genes,Wong-2019-Suppression of Alternative Lipooligo,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14221,PHI:9263,UniProt,Q03974,GenBank,AAA65534,,,RM7004,lic2A,,,,,,PHI:9264,727,Haemophilus influenzae,,NTHi 375,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,glycosyltransferase involved in LPS biosynthesis,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31157175,PubMed,10.3389/fcimb.2019.00160,Front Cell Infect Microbiol. 2019 May 15;9:160,bakerley@umc.edu,The galE mutants exhibited restored virulence properties in a lic2A mutant background.,S M Wong 2019,2019,2 genes,Wong-2019-Suppression of Alternative Lipooligo,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14222,PHI:9264,UniProt,P24325,GenBank,CAA40568,,,RM.7004,galE,,,,,,PHI:9263,727,Haemophilus influenzae,,NTHi 375,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,UDP-glucose 4-epimerase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31157175,PubMed,10.3389/fcimb.2019.00160,Front Cell Infect Microbiol. 2019 May 15;9:160,bakerley@umc.edu,The galE mutants exhibited restored virulence properties in a lic2A mutant background.,S M Wong 2019,2019,2 genes,Wong-2019-Suppression of Alternative Lipooligo,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14223,PHI:9265,UniProt,V9TKV7,GenBank,AHC70491,,,ITEM 2287,FUM1,,,,,,,948311,Fusarium proliferatum,,FP9,root rot,monocots,4530,Oryza sativa (related: rice),cv. Xiushui 134,,,spikelet,fumonisin biosynthetic polyketide synthase,,,fumonisin biosynthesis,reduced virulence,,,,,,increased,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31181598,PubMed,10.3390/toxins11060327,Toxins (Basel). 2019 Jun 7;11(6),huangshiwen@caas.cn,Inhibition of the synthesis of the mycotoxin fumonisin weakened the pathogenicity of rice spikelet rot disease (RSRD).,L Sun 2019,2019,5 genes,Sun-2019-Effects of Disruption of Five FUM Gen,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14224,PHI:9266,UniProt,V9TM92,GenBank,AHC70507,,,ITEM 2287,FUM6,,,,,,,948311,Fusarium proliferatum,,FP9,root rot,monocots,4530,Oryza sativa (related: rice),cv. Xiushui 134,,,spikelet,"fumonisin C-14,C15-hydroxylase",,,fumonisin biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31181598,PubMed,10.3390/toxins11060327,Toxins (Basel). 2019 Jun 7;11(6),huangshiwen@caas.cn,Inhibition of the synthesis of the mycotoxin fumonisin weakened the pathogenicity of rice spikelet rot disease (RSRD).,L Sun 2019,2019,5 genes,Sun-2019-Effects of Disruption of Five FUM Gen,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14225,PHI:9267,UniProt,B1GXZ2,GenBank,CAQ16828,,,Fpro-278,FUM8,,,,,,,948311,Fusarium proliferatum,,FP9,root rot,monocots,4530,Oryza sativa (related: rice),cv. Xiushui 134,,,spikelet,oxamine synthase,,,fumonisin biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31181598,PubMed,10.3390/toxins11060327,Toxins (Basel). 2019 Jun 7;11(6),huangshiwen@caas.cn,Inhibition of the synthesis of the mycotoxin fumonisin weakened the pathogenicity of rice spikelet rot disease (RSRD).,L Sun 2019,2019,5 genes,Sun-2019-Effects of Disruption of Five FUM Gen,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14226,PHI:9268,UniProt,V9TMT1,GenBank,AHC70697,,,ITEM 2287,FUM19,,,,,,,948311,Fusarium proliferatum,,FP9,root rot,monocots,4530,Oryza sativa (related: rice),cv. Xiushui 134,,,spikelet,fumonisin biosynthetic ABC transporter,,,,reduced virulence,,,,,,increased,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31181598,PubMed,10.3390/toxins11060327,Toxins (Basel). 2019 Jun 7;11(6),huangshiwen@caas.cn,Inhibition of the synthesis of the mycotoxin fumonisin weakened the pathogenicity of rice spikelet rot disease (RSRD).,L Sun 2019,2019,5 genes,Sun-2019-Effects of Disruption of Five FUM Gen,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14227,PHI:9269,UniProt,V9TNW6,GenBank,AHC70694,,,ITEM 2287,FUM21,,,,,,,948311,Fusarium proliferatum,,FP9,root rot,monocots,4530,Oryza sativa (related: rice),cv. Xiushui 134,,,spikelet,fumonisin biosynthetic transcription factor,,,fumonisin biosynthesis,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31181598,PubMed,10.3390/toxins11060327,Toxins (Basel). 2019 Jun 7;11(6),huangshiwen@caas.cn,Inhibition of the synthesis of the mycotoxin fumonisin weakened the pathogenicity of rice spikelet rot disease (RSRD).,L Sun 2019,2019,5 genes,Sun-2019-Effects of Disruption of Five FUM Gen,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14228,PHI:9270,UniProt,A4VWD1,GenBank,ABP90420,,,05ZYH33,mnmE,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; lung; spleen; blood,central tRNA-modifying GTPase,,,arginine metabolic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31179247,PubMed,10.3389/fcimb.2019.00173,Front Cell Infect Microbiol. 2019 May 24;9:173,rzhou@mail.hzau.edu.cn,"The ΔmnmE strain displayed deficient growth, attenuated pathogenicity, and perturbation of the arginine metabolic pathway mediated by the arginine deiminase system (ADS).",T Gao 2019,2019,1 gene,"Gao-2019-MnmE, a Central tRNA-Modifying GTPase",BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14229,PHI:9270,UniProt,A4VWD1,GenBank,ABP90420,,,05ZYH33,mnmE,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,central tRNA-modifying GTPase,,,arginine metabolic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31179247,PubMed,10.3389/fcimb.2019.00173,Front Cell Infect Microbiol. 2019 May 24;9:173,rzhou@mail.hzau.edu.cn,The inactivation of mnmE impaired the capacity of S. suis to adhere to and invade in epithelial cells.,T Gao 2019,2019,1 gene,"Gao-2019-MnmE, a Central tRNA-Modifying GTPase",BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14230,PHI:9271,UniProt,Q6FW72,GenBank,CAG58433,,,CBS 138,Cgfig4 (CAGL0D02464g),chromosome D,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage; liver; spleen; brain,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,fluconazole; congo red; calcofluor white; zinc chloride; caspofungin,fluconazole: CHEBI:46081; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; zinc chloride: CHEBI:49976; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31138567,PubMed,10.1128/AAC.00886-19,Antimicrob Agents Chemother. 2019 May 28,rkaur@cdfd.org.in,"Three main components of the PI(3,5)P2 regulatory complex, CgFab1, CgVac7 and CgVac14, were required for maintenance of the cell wall composition and survival of the cell wall and caspofungin stress in C. glabrata.",D K Choudhary 2019,2019,4 genes,Choudhary-2019-An essential role for the PI(3,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14231,PHI:9272,UniProt,Q6FTM4,GenBank,CAG59347,,,CBS 138,Cgvac7 (CAGL0G01342g),chromosome G,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage; kidney; liver; spleen; brain,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,fluconazole; congo red; calcofluor white; zinc chloride; caspofungin,fluconazole: CHEBI:46081; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; zinc chloride: CHEBI:49976; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31138567,PubMed,10.1128/AAC.00886-19,Antimicrob Agents Chemother. 2019 May 28,rkaur@cdfd.org.in,"Three main components of the PI(3,5)P2 regulatory complex, CgFab1, CgVac7 and CgVac14, were required for maintenance of the cell wall composition and survival of the cell wall and caspofungin stress in C. glabrata.",D K Choudhary 2019,2019,4 genes,Choudhary-2019-An essential role for the PI(3,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14232,PHI:9273,UniProt,Q6FRR6,GenBank,CAG60011,,,CBS 138,Cgvac14 (CAGL0H06501g),chromosome H,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage; brain; kidney,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,fluconazole; congo red; calcofluor white; zinc chloride; caspofungin,fluconazole: CHEBI:46081; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; zinc chloride: CHEBI:49976; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31138567,PubMed,10.1128/AAC.00886-19,Antimicrob Agents Chemother. 2019 May 28,rkaur@cdfd.org.in,"Three main components of the PI(3,5)P2 regulatory complex, CgFab1, CgVac7 and CgVac14, were required for maintenance of the cell wall composition and survival of the cell wall and caspofungin stress in C. glabrata.",D K Choudhary 2019,2019,4 genes,Choudhary-2019-An essential role for the PI(3,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14233,PHI:9274,UniProt,Q6FM73,GenBank,XP_448671,,,CBS 138,Cgfab1,chromosome K,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage; kidney; liver; spleen; brain,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,fluconazole; congo red; calcofluor white; zinc chloride; caspofungin,fluconazole: CHEBI:46081; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; zinc chloride: CHEBI:49976; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31138567,PubMed,10.1128/AAC.00886-19,Antimicrob Agents Chemother. 2019 May 28,rkaur@cdfd.org.in,"Three main components of the PI(3,5)P2 regulatory complex, CgFab1, CgVac7 and CgVac14, were required for maintenance of the cell wall composition and survival of the cell wall and caspofungin stress in C. glabrata.",D K Choudhary 2019,2019,4 genes,Choudhary-2019-An essential role for the PI(3,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14234,PHI:9271,UniProt,Q6FW72,GenBank,CAG58433,,,CBS 138,Cgfig4 (CAGL0D02464g),chromosome D,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,fluconazole; congo red; calcofluor white; zinc chloride; caspofungin,fluconazole: CHEBI:46081; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; zinc chloride: CHEBI:49976; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31138567,PubMed,10.1128/AAC.00886-19,Antimicrob Agents Chemother. 2019 May 28,rkaur@cdfd.org.in,"Three main components of the PI(3,5)P2 regulatory complex, CgFab1, CgVac7 and CgVac14, were required for maintenance of the cell wall composition and survival of the cell wall and caspofungin stress in C. glabrata.",D K Choudhary 2019,2019,4 genes,Choudhary-2019-An essential role for the PI(3,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14235,PHI:9273,UniProt,Q6FRR6,GenBank,CAG60011,,,CBS 138,Cgvac14 (CAGL0H06501g),chromosome H,,,,,,5478,Candida glabrata,,BG2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,fluconazole; congo red; calcofluor white; zinc chloride; caspofungin,fluconazole: CHEBI:46081; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; zinc chloride: CHEBI:49976; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31138567,PubMed,10.1128/AAC.00886-19,Antimicrob Agents Chemother. 2019 May 28,rkaur@cdfd.org.in,"Three main components of the PI(3,5)P2 regulatory complex, CgFab1, CgVac7 and CgVac14, were required for maintenance of the cell wall composition and survival of the cell wall and caspofungin stress in C. glabrata.",D K Choudhary 2019,2019,4 genes,Choudhary-2019-An essential role for the PI(3,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14236,PHI:9275,UniProt,E4TDE3,GenBank,AFD56812,,,ATCC 11845,gldM (AS87_RS08465),,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,chronic septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood,protein involved in gliding motility,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31164171,PubMed,10.1186/s13567-019-0660-0,Vet Res. 2019 Jun 4;50(1):43,yus@shvri.ac.cn,Yb2ΔgldM was found to be defective in gliding motility and protein secretion.,Z Chen 2019,2019,1 gene,Chen-2019-Riemerella anatipestifer GldM is req,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14237,PHI:9275,UniProt,E4TDE3,GenBank,AFD56812,,,ATCC 11845,gldM (AS87_RS08465),,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,chronic septicemia,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,protein involved in gliding motility,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31164171,PubMed,10.1186/s13567-019-0660-0,Vet Res. 2019 Jun 4;50(1):43,yus@shvri.ac.cn,Deletion of gldM reduced bacterial adherence and invasion capacities.,Z Chen 2019,2019,1 gene,Chen-2019-Riemerella anatipestifer GldM is req,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14238,PHI:9276,UniProt,Q4WND8,GenBank,Afu6g06710,,,,cdc43,,,,,,,746128,Aspergillus fumigatus,,ku80 ΔpyrG,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,protein geranylgeranyltransferase type I subunit,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; nikkomycin Z; caspofungin,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; nikkomycin Z: CHEBI:623918; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31131706,PubMed,10.1080/21505594.2019.1620063,Virulence. 2019 Dec;10(1):511-526,jfortwen@uthsc.edu,"Studies with A. fumigatus established that ramB, but not cdc43, was essential for virulence.",A C O Souza 2019,2019,4 genes,Souza-2019-Differential requirements of protei,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14239,PHI:9277,,no data found,,,,,,ramB,,,,,,,746128,Aspergillus fumigatus,,ku80 ΔpyrG,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; nikkomycin Z; caspofungin,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; nikkomycin Z: CHEBI:623918; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,31131706,PubMed,10.1080/21505594.2019.1620063,Virulence. 2019 Dec;10(1):511-526,jfortwen@uthsc.edu,"Studies with A. fumigatus established that ramB, but not cdc43, was essential for virulence.",A C O Souza 2019,2019,4 genes,Souza-2019-Differential requirements of protei,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14240,PHI:9278,UniProt,A0A1D8PSW8,GenBank,AOW31224,,,SC5314,CDC43,chromosome R,tetracycline repressible expression of CDC43 (PTETO-CDC43),,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,protein geranylgeranyltransferase type I subunit,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; nikkomycin Z; caspofungin,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; nikkomycin Z: CHEBI:623918; caspofungin: CHEBI:474180,,,,,gene mutation,,,YVS,31131706,PubMed,10.1080/21505594.2019.1620063,Virulence. 2019 Dec;10(1):511-526,jfortwen@uthsc.edu,"Only 1 of 7 PTETO-CDC43 infected mice, and none of the PTETO-RAM2 infected mice succumbed to infection in the doxycycline treatment group.",A C O Souza 2019,2019,4 genes,Souza-2019-Differential requirements of protei,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14241,PHI:9279,UniProt,Q9Y765,GenBank,AF110691_1,,,,ram2,,tetracycline repressible expression of RAM2 (PTETO-RAM2),,,,,5476,Candida albicans,,,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; nikkomycin Z; caspofungin,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; nikkomycin Z: CHEBI:623918; caspofungin: CHEBI:474180,,,,,gene mutation,,,YVS,31131706,PubMed,10.1080/21505594.2019.1620063,Virulence. 2019 Dec;10(1):511-526,jfortwen@uthsc.edu,"Only 1 of 7 PTETO-CDC43 infected mice, and none of the PTETO-RAM2 infected mice succumbed to infection in the doxycycline treatment group.",A C O Souza 2019,2019,4 genes,Souza-2019-Differential requirements of protei,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14242,PHI:9280,UniProt,Q9HTY6,GenBank,AE004933_4,,,PAO1,gshA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,glutamate-cysteine ligase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,YVS,31157178,PubMed,10.3389/fcimb.2019.00164,Front Cell Infect Microbiol. 2019 May 16;9:164,lianghh@nwu.edu.cn,"The ΔgshAΔgshB was attenuated in a mouse model of acute pneumonia, swimming and swarming motilities, and biofilm formation.",Y Zhang 2019,2019,2 genes,Zhang-2019-Glutathione Activates Type III Secr,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14243,PHI:9281,UniProt,Q9I697,GenBank,AE004478_1,,,PAO1,gshB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,glutathione synthetase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,YVS,31157178,PubMed,10.3389/fcimb.2019.00164,Front Cell Infect Microbiol. 2019 May 16;9:164,lianghh@nwu.edu.cn,"The ΔgshAΔgshB was attenuated in a mouse model of acute pneumonia, swimming and swarming motilities, and biofilm formation.",Y Zhang 2019,2019,2 genes,Zhang-2019-Glutathione Activates Type III Secr,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14244,PHI:9280,UniProt,Q9HTY6,GenBank,AE004933_4,,,PAO1,gshA,,,,,,PHI:9281,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,glutamate-cysteine ligase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,YVS,31157178,PubMed,10.3389/fcimb.2019.00164,Front Cell Infect Microbiol. 2019 May 16;9:164,lianghh@nwu.edu.cn,"The ΔgshAΔgshB was attenuated in a mouse model of acute pneumonia, swimming and swarming motilities, and biofilm formation.",Y Zhang 2019,2019,2 genes,Zhang-2019-Glutathione Activates Type III Secr,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14245,PHI:9281,UniProt,Q9I697,GenBank,AE004478_1,,,PAO1,gshB,,,,,,PHI:9280,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,glutathione synthetase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion; gene complementation,,,YVS,31157178,PubMed,10.3389/fcimb.2019.00164,Front Cell Infect Microbiol. 2019 May 16;9:164,lianghh@nwu.edu.cn,"The ΔgshAΔgshB was attenuated in a mouse model of acute pneumonia, swimming and swarming motilities, and biofilm formation.",Y Zhang 2019,2019,2 genes,Zhang-2019-Glutathione Activates Type III Secr,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14246,PHI:9282,UniProt,A0A384JIS4,GenBank,ATZ50499,,,B05.10,mfsG (BCIN_06g00026),chromosome BCIN06,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,major facilitator superfamily transporter,,,,reduced virulence,,,,,,,,,,no,propyl isothiocyanate; benzyl isothiocyanate; 2-phenethyl isothiocyanate,propyl isothiocyanate CAS no.: CAS:628-30-8; benzyl isothiocyanate: CHEBI:17484; 2-phenethyl isothiocyanate: CHEBI:351346,,,,,gene deletion: full; gene complementation,,,YVS,31253809,PubMed,10.1038/s41467-019-10860-3,Nat Commun. 2019 Jun 28;10(1):2886,maggie.levy@mail.huji.ac.il,A B. cinerea strain lacking functional mfsG transporter was deficient in efflux ability and accumulated more isothiocyanates (ITCs) and was therefore more sensitive to this compound in vitro; it was also less virulent to glucosinolates-containing plants.,D Vela-Corcia 2019,2019,1 gene,Vela-Corcia-2019-MFS transporter from Botrytis,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14247,PHI:9283,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,ompAD268A,,,,,470,Acinetobacter baumannii,,Ab169,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31121924,PubMed,10.3390/molecules24101972,Molecules. 2019 May 22;24(10),jurate.skerniskyte@gf.vu.lt,"The Ab169 OmpA D268-mediated association to peptidoglycan was required for the manifestation of twitching motility, desiccation resistance, serum-induced killing, adhesion to epithelial cells and virulence in a nematode infection model",J Skerniskyte 2019,2019,1 gene,Skerniskyte-2019-The Mutation of Conservative,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14248,PHI:9283,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,ompAD268A,,,,,470,Acinetobacter baumannii,,Ab169,pneumonia,rodents,10090,Mus musculus (related: house mouse),LL/2 (LLC1) cell line,,,lung epithelial cell,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31121924,PubMed,10.3390/molecules24101972,Molecules. 2019 May 22;24(10),jurate.skerniskyte@gf.vu.lt,"The Ab169 OmpA D268-mediated association to peptidoglycan was required for the manifestation of twitching motility, desiccation resistance, serum-induced killing, adhesion to epithelial cells and virulence in a nematode infection model",J Skerniskyte 2019,2019,1 gene,Skerniskyte-2019-The Mutation of Conservative,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14249,PHI:9283,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,,,,,,470,Acinetobacter baumannii,,Ab169,pneumonia,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31121924,PubMed,10.3390/molecules24101972,Molecules. 2019 May 22;24(10),jurate.skerniskyte@gf.vu.lt,"The Ab169 OmpA D268-mediated association to peptidoglycan was required for the manifestation of twitching motility, desiccation resistance, serum-induced killing, adhesion to epithelial cells and virulence in a nematode infection model",J Skerniskyte 2019,2019,1 gene,Skerniskyte-2019-The Mutation of Conservative,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14250,PHI:9283,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,,,,,,470,Acinetobacter baumannii,,Ab169,pneumonia,rodents,10090,Mus musculus (related: house mouse),LL/2 (LLC1) cell line,,,lung epithelial cell,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31121924,PubMed,10.3390/molecules24101972,Molecules. 2019 May 22;24(10),jurate.skerniskyte@gf.vu.lt,"The Ab169 OmpA D268-mediated association to peptidoglycan was required for the manifestation of twitching motility, desiccation resistance, serum-induced killing, adhesion to epithelial cells and virulence in a nematode infection model",J Skerniskyte 2019,2019,1 gene,Skerniskyte-2019-The Mutation of Conservative,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14251,PHI:9284,UniProt,Q59PZ5,GenBank,AOW31368,,,SC5314,gcn5,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage; myeloid dendritic cell,histone acetyl transferase,,,,loss of pathogenicity,,,,,,,,,,no,caspofungin; caffeine; SDS; Congo red; hydrogen peroxide; itraconazole; fuconazole; ketoconazole; voriconazole,caspofungin: CHEBI:474180; caffeine: CHEBI:27732; SDS: CHEBI:8984; Congo red: CHEBI:34653; hydrogen peroxide: CHEBI:16240; itraconazole: CHEBI:6076; fluconazole: CHEBI:46081; ketoconazole: CHEBI:48336; voriconazole: CHEBI:10023,,,,,gene deletion: full; gene complementation,,,YVS,31263212,PubMed,10.1038/s41598-019-45817-5,Sci Rep. 2019 Jul 1;9(1):9445,karl.kuchler@meduniwien.ac.at,Gcn5 was required for intracellular survival in BMDMs and essential for fungal virulence.,R Shivarathri 2019,2019,1 gene,Shivarathri-2019-The Fungal Histone Acetyl Tra,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14252,PHI:9285,UniProt,V5VGM8,GenBank,AKA32972,,,AB5075-UW,trxA,,,,,,,470,Acinetobacter baumannii,,CI79,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen; blood,thioredoxin A,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,31265467,PubMed,10.1371/journal.pone.0218505,PLoS One. 2019 Jul 2;14(7):e0218505,bernard.arulanandam@utsa.edu,Lack of TrxA was associated with decreased expression of type IV pili related genes and an inability to undergo normal twitching motility.,H C May 2019,2019,1 gene,May-2019-Thioredoxin-A is a virulence factor a,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14253,PHI:9286,,no data found,,,,,,dicF,,,,,,,562,Escherichia coli,,serotype O157:H7 strain 86-24,urinary tract infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,small RNA,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31235565,PubMed,10.1073/pnas.1902725116,Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14210-14215,melissakendall@virginia.edu,ΔDicF strain was attenuated for AE lesion formation in HeLa cells.,E M Melson 2019,2019,1 gene,Melson-2019-The sRNA DicF integrates oxygen se,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14254,PHI:9287,UniProt,A0A0J9W5C7,GenBank,KNB18234,,,4287,rad21nc (FOXG_15850),chromosome 8,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,seedling,hypothetical protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,methyl methanesulfonate (MMS); benomyl; hydroxyurea,methyl methanesulfonate: CHEBI:25255; benomyl: CHEBI:3015; hydroxyurea: CHEBI:44423,,,,,gene deletion: full,,,YVS,31275285,PubMed,10.3389/fmicb.2019.01370,Front Microbiol. 2019 Jun 18;10:1370,shay.covo@mail.huji.ac.il,"ΔRad21nc and 1rec8 single mutants were proficient in sporulation, conidia germination, hyphal growth and pathogenicity under optimal growth conditions.",M Pareek 2019,2019,2 genes,Pareek-2019-Alternative Functional rad21 Paral,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14255,PHI:9288,UniProt,A0A0D2XHJ2,GenBank,KNA99462,,,4287,rec8 (FOXG_03390),chromosome 8,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,seedling,hypothetical protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,methyl methanesulfonate (MMS); benomyl; hydroxyurea,methyl methanesulfonate: CHEBI:25255; benomyl: CHEBI:3015; hydroxyurea: CHEBI:44423,,,,,gene deletion: full,,,YVS,31275285,PubMed,10.3389/fmicb.2019.01370,Front Microbiol. 2019 Jun 18;10:1370,shay.covo@mail.huji.ac.il,"ΔRad21nc and 1rec8 single mutants were proficient in sporulation, conidia germination, hyphal growth and pathogenicity under optimal growth conditions.",M Pareek 2019,2019,2 genes,Pareek-2019-Alternative Functional rad21 Paral,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14256,PHI:9289,UniProt,C5AD21,GenBank,ACR30136,,,BGR1,PVF11 (bglu_1g30730),chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,seedling; stem,putative TetR family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31244573,PubMed,10.5423/PPJ.NT.02.2019.0026,Plant Pathol J. 2019 Jun;35(3):280-286,yseo2011@pusan.ac.kr,"PVF11 defective mutant showed reduced virulence in rice seedlings and stems but not in rice panicles, indicating that PVF11 involvement in B. glumae virulence in rice was stage-dependent.",J Kim 2019,2019,1 gene,Kim-2019-Characterization of Burkholderia glum,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14257,PHI:9289,UniProt,C5AD21,GenBank,ACR30136,,,BGR1,PVF11 (bglu_1g30730),chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,panicle,putative TetR family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31244573,PubMed,10.5423/PPJ.NT.02.2019.0026,Plant Pathol J. 2019 Jun;35(3):280-286,yseo2011@pusan.ac.kr,"PVF11 defective mutant showed reduced virulence in rice seedlings and stems but not in rice panicles, indicating that PVF11 involvement in B. glumae virulence in rice was stage-dependent.",J Kim 2019,2019,1 gene,Kim-2019-Characterization of Burkholderia glum,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14258,PHI:9290,UniProt,G4MY67,GenBank,EHA54398,,,70-15,RAM1 (MGG_01287T0),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,farnesyltransferase beta-subunit,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,reduced,no,tipifarnib; calcofluor white (CFW); Congo red (CR); sodium dodecyl sulphate (SDS); H2O2; NaCl; 3-isobutyl-1-methylxanthine (IBMX),tipifarnib: CHEBI:141969; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulphate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:26710; 3-isobutyl-1-methylxanthine (IBMX): CHEBI:48518,,,,,gene deletion: full; gene complementation,,,YVS,31250536,PubMed,10.1111/mpp.12838,Mol Plant Pathol. 2019 Jun 27,chenxiaolin@mail.hzau.edu.cn,"Targeted disruption of RAM1 resulted in the reduction of hyphal growth and sporulation, and an increase in the sensitivity to various stresses.",A A Hendy 2019,2019,1 gene,Aboelfotoh Hend-2019-The farnesyltransferase b,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14259,PHI:9290,UniProt,G4MY67,GenBank,EHA54398,,,70-15,RAM1 (MGG_01287T0),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,farnesyltransferase beta-subunit,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,reduced,no,tipifarnib; calcofluor white (CFW); Congo red (CR); sodium dodecyl sulphate (SDS); H2O2; NaCl; 3-isobutyl-1-methylxanthine (IBMX),tipifarnib: CHEBI:141969; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulphate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:26710; 3-isobutyl-1-methylxanthine (IBMX): CHEBI:48518,,,,,gene deletion: full; gene complementation,,,YVS,31250536,PubMed,10.1111/mpp.12838,Mol Plant Pathol. 2019 Jun 27,chenxiaolin@mail.hzau.edu.cn,"Targeted disruption of RAM1 resulted in the reduction of hyphal growth and sporulation, and an increase in the sensitivity to various stresses.",A A Hendy 2019,2019,1 gene,Aboelfotoh Hend-2019-The farnesyltransferase b,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14260,PHI:9291,UniProt,A0A0H3PAL0,GenBank,EAQ72738,,,81-176,cadF,,,,,,,197,Campylobacter jejuni,,81-176,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-10<-/->),,,stomach; duodenum; ileum; colon; liver; lung; spleen; mesenteric lymph node,adhesin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31131028,PubMed,10.1186/s13099-019-0306-9,Gut Pathog. 2019 May 17;11:24,markus.heimesaat@charite.de,"C. jejuni flagellins A/B, but not adhesion mediated by CadF, were essential for inducing murine campylobacteriosis.",A M Schmidt 2019,2019,3 genes,Schmidt-2019-Immunopathological properties of,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14261,PHI:9291,UniProt,A0A0H3PAL0,GenBank,EAQ72738,,,81-176,cadF,,,,,,,197,Campylobacter jejuni,,81-176,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-10<-/->),,,kidney,adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31131028,PubMed,10.1186/s13099-019-0306-9,Gut Pathog. 2019 May 17;11:24,markus.heimesaat@charite.de,"C. jejuni flagellins A/B, but not adhesion mediated by CadF, were essential for inducing murine campylobacteriosis.",A M Schmidt 2019,2019,3 genes,Schmidt-2019-Immunopathological properties of,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14262,PHI:9292,UniProt,P22251,GenBank,AAA23024,,,81116,flaA,,,,,,PHI:9293,197,Campylobacter jejuni,,81-176,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-10<-/->),,,stomach; duodenum; ileum; liver; lung; spleen; kidney; mesenteric lymph node,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31131028,PubMed,10.1186/s13099-019-0306-9,Gut Pathog. 2019 May 17;11:24,markus.heimesaat@charite.de,"C. jejuni flagellins A/B, but not adhesion mediated by CadF, were essential for inducing murine campylobacteriosis.",A M Schmidt 2019,2019,3 genes,Schmidt-2019-Immunopathological properties of,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14263,PHI:9293,UniProt,P22252,GenBank,AAA23025,,,81116,flaB,,,,,,PHI:9292,197,Campylobacter jejuni,,81-176,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-10<-/->),,,stomach; duodenum; ileum; liver; lung; spleen; kidney,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31131028,PubMed,10.1186/s13099-019-0306-9,Gut Pathog. 2019 May 17;11:24,markus.heimesaat@charite.de,"C. jejuni flagellins A/B, but not adhesion mediated by CadF, were essential for inducing murine campylobacteriosis.",A M Schmidt 2019,2019,3 genes,Schmidt-2019-Immunopathological properties of,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14264,PHI:9292,UniProt,P22251,GenBank,AAA23024,,,81116,flaA,,,,,,PHI:9293,197,Campylobacter jejuni,,81-176,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-10<-/->),,,colon,flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31131028,PubMed,10.1186/s13099-019-0306-9,Gut Pathog. 2019 May 17;11:24,markus.heimesaat@charite.de,"C. jejuni flagellins A/B, but not adhesion mediated by CadF, were essential for inducing murine campylobacteriosis.",A M Schmidt 2019,2019,3 genes,Schmidt-2019-Immunopathological properties of,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14265,PHI:9293,UniProt,P22252,GenBank,AAA23025,,,81116,flaB,,,,,,PHI:9292,197,Campylobacter jejuni,,81-176,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-10<-/->),,,colon,flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31131028,PubMed,10.1186/s13099-019-0306-9,Gut Pathog. 2019 May 17;11:24,markus.heimesaat@charite.de,"C. jejuni flagellins A/B, but not adhesion mediated by CadF, were essential for inducing murine campylobacteriosis.",A M Schmidt 2019,2019,3 genes,Schmidt-2019-Immunopathological properties of,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14266,PHI:9294,UniProt,Q88A90,GenBank,AAO54046,,,DC3000,HopF2,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,31148337,PubMed,10.1111/tpj.14425,Plant J. 2019 May 31,darrell.desveaux@utoronto.ca,The type III secreted effectors (T3SEs) HopF2Pto and HopF3Pph6 promoted abscisic acid (ABA) hypersensitivity and enhanced pathogen susceptibility.,F Y Cao 2019,2019,2 genes,Cao-2019-A host-pathogen interactome uncovers,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14267,PHI:9295,UniProt,Q48G35,GenBank,AAZ37227,,,1448A; BAA-978,HopF3,,,,,,,317,Pseudomonas syringae,,pv. phaseolicola race 6,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,31148337,PubMed,10.1111/tpj.14425,Plant J. 2019 May 31,darrell.desveaux@utoronto.ca,The type III secreted effectors (T3SEs) HopF2Pto and HopF3Pph6 promoted abscisic acid (ABA) hypersensitivity and enhanced pathogen susceptibility.,F Y Cao 2019,2019,2 genes,Cao-2019-A host-pathogen interactome uncovers,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14268,PHI:9296,,no data found,GenBank,BAV54653,,,JMUB1235,mtsR,,,,,,,1314,Streptococcus pyogenes,530008,MGAS10870,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,DtxR family metal-dependent transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene disruption; gene complementation,,,YVS,31188450,PubMed,10.1093/nar/gkz524,Nucleic Acids Res. 2019 Jun 12,mkumaraswami@houstonmethodist.org,The mtsR mutant strains defective in metal sensing and oligomerization were attenuated for virulence in a mouse model of invasive infection.,H Do 2019,2019,1 gene,Do-2019-Metal sensing and regulation of adapti,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14269,PHI:9297,UniProt,A0A384JDU6,GenBank,ATZ48597,,,B05.10,Bcexo70,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,exocyst complex protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31183512,PubMed,10.1007/s00294-019-01002-9,Curr Genet. 2019 Jun 10,thzhu@zjut.edu.cn,Knockout of the Bcexo70 gene significantly reduced the fungal growth and hindered the production of conidia and sclerotia.,W Guan 2019,2019,1 gene,Guan-2019-Functional analysis of the exocyst s,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14270,PHI:9298,UniProt,A0A0A2JW21,GenBank,KGO56415,,,MD-8,Penlp1 (PEX2_080220),,,,,,,27334,Penicillium expansum,,PEX2,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,necrosis inducing protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31208074,PubMed,10.3390/microorganisms7060175,Microorganisms. 2019 Jun 15;7(6),samird@volcani.agri.gov.il,"Deletion of Penlp1, but not Penlp2, resulted in reduced virulence on apples manifested by reduced rate of lesion development.",E Levin 2019,2019,2 genes,Levin-2019-Identification and Functional Analy,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14271,PHI:9299,UniProt,A0A0A2JGQ7,GenBank,KGO54582,,,MD-8,Penlp2 (PEX2_071150),,,,,,,27334,Penicillium expansum,,PEX2,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,necrosis inducing protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31208074,PubMed,10.3390/microorganisms7060175,Microorganisms. 2019 Jun 15;7(6),samird@volcani.agri.gov.il,"Deletion of Penlp1, but not Penlp2, resulted in reduced virulence on apples manifested by reduced rate of lesion development.",E Levin 2019,2019,2 genes,Levin-2019-Identification and Functional Analy,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14272,PHI:9298,UniProt,A0A0A2JW21,GenBank,KGO56415,,,MD-8,Penlp1 (PEX2_080220),,,,,,,27334,Penicillium expansum,,PEX2,blue mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,necrosis inducing protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,functional test in host: transient expression,,,YVS,31208074,PubMed,10.3390/microorganisms7060175,Microorganisms. 2019 Jun 15;7(6),samird@volcani.agri.gov.il,"Deletion of Penlp1, but not Penlp2, resulted in reduced virulence on apples manifested by reduced rate of lesion development.",E Levin 2019,2019,2 genes,Levin-2019-Identification and Functional Analy,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14273,PHI:9299,UniProt,A0A0A2JGQ7,GenBank,KGO54582,,,MD-8,Penlp2 (PEX2_071150),,,,,,,27334,Penicillium expansum,,PEX2,blue mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,necrosis inducing protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,functional test in host: transient expression,,,YVS,31208074,PubMed,10.3390/microorganisms7060175,Microorganisms. 2019 Jun 15;7(6),samird@volcani.agri.gov.il,"Deletion of Penlp1, but not Penlp2, resulted in reduced virulence on apples manifested by reduced rate of lesion development.",E Levin 2019,2019,2 genes,Levin-2019-Identification and Functional Analy,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14274,PHI:9300,UniProt,P0DJM0,GenBank,CAC20628,,,EGD,inlA,,Premature stop codon (PMSC) mutation in inlA,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,internalin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31206562,PubMed,10.1371/journal.ppat.1007841,PLoS Pathog. 2019 Jun 17;15(6):e1007841,mewats@med.umich.edu,The PMSC mutations in inlA correlated with the inability of the L. monocytogenes isolates to invade Caco-2 cells.,T M Nye 2019,2019,1 gene,Nye-2019-DNA methylation from a Type I restric,BATCH_094A,2019-07-01,MC,,,,,,,,,,,,,
,,Record 14275,PHI:9301,UniProt,G4N7U4,GenBank,EHA50898,,,70-15,Modnm1 (MGG_06361),chromosome 4,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,dynamin-A,,,,reduced virulence,,,yes,yes,,,,,,no,N-acetyl-L-cysteine,N-acetyl-L-cysteine: CHEBI:28939,,,,,gene deletion: full; gene complementation,,,YVS,31218796,PubMed,10.1111/mpp.12822,Mol Plant Pathol. 2019 Aug;20(8):1147-1162,naweed@tll.org.sg,"Characterization of Modnm1Δ, Mofzo1Δ and Moatg24Δ strains, and Mdivi-1-based chemical inhibition of mitochondrial division revealed that mitochondrial fusion and fission machineries and mitophagy were required for maintaining mitochondrial dynamics and were necessary for proper infection and pathogenesis in M. oryzae.",Y Kou 2019,2019,3 genes,Kou-2019-Mitochondrial dynamics and mitophagy,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14276,PHI:9302,UniProt,G4N536,GenBank,EHA52947,,,70-15,Mofzo1 (MGG_05209),chromosome 3,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,transmembrane GTPase,,,,reduced virulence,,,yes,yes,,,,,,no,N-acetyl-L-cysteine,N-acetyl-L-cysteine: CHEBI:28939,,,,,gene deletion: full; gene complementation,,,YVS,31218796,PubMed,10.1111/mpp.12822,Mol Plant Pathol. 2019 Aug;20(8):1147-1162,naweed@tll.org.sg,"Characterization of Modnm1Δ, Mofzo1Δ and Moatg24Δ strains, and Mdivi-1-based chemical inhibition of mitochondrial division revealed that mitochondrial fusion and fission machineries and mitophagy were required for maintaining mitochondrial dynamics and were necessary for proper infection and pathogenesis in M. oryzae.",Y Kou 2019,2019,3 genes,Kou-2019-Mitochondrial dynamics and mitophagy,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14277,PHI:9303,UniProt,Q522W5,GenBank,EHA49932,,,70-15,Moatg24 (XP_003716251.1),chromosome 4,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,sorting nexin-4,,,,reduced virulence,,,yes,yes,,,,,,no,N-acetyl-L-cysteine,N-acetyl-L-cysteine: CHEBI:28939,,,,,gene deletion: full; gene complementation,,,YVS,31218796,PubMed,10.1111/mpp.12822,Mol Plant Pathol. 2019 Aug;20(8):1147-1162,naweed@tll.org.sg,"Characterization of Modnm1Δ, Mofzo1Δ and Moatg24Δ strains, and Mdivi-1-based chemical inhibition of mitochondrial division revealed that mitochondrial fusion and fission machineries and mitophagy were required for maintaining mitochondrial dynamics and were necessary for proper infection and pathogenesis in M. oryzae.",Y Kou 2019,2019,3 genes,Kou-2019-Mitochondrial dynamics and mitophagy,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14278,PHI:9304,,no data found,GenBank,AVT56810,,,3-2,wcaG,,,,,,,554,Pectobacterium carotovorum,555,subsp. carotovorum strain Ecc71,soft rot,eudicots,4045,Apium graveolens (no common name found),dulce group,,,petiole,NAD-dependent epimerase/dehydratase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31200539,PubMed,10.3390/microorganisms7060172,Microorganisms. 2019 Jun 13;7(6),ataheri1@tnstate.edu,"WcaG mutants macerated less tissue of celery petioles and carrot root discs in comparison with the parental strain, but did not affect the survival and multiplication ability of the pathogen.",R Islam 2019,2019,1 gene,Islam-2019-The Gene Encoding NAD-Dependent Epi,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14279,PHI:9304,,no data found,GenBank,AVT56810,,,3-2,wcaG,,,,,,,554,Pectobacterium carotovorum,555,subsp. carotovorum strain Ecc71,soft rot,eudicots,4039,Daucus carota (related: carrot),,,,root,NAD-dependent epimerase/dehydratase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31200539,PubMed,10.3390/microorganisms7060172,Microorganisms. 2019 Jun 13;7(6),ataheri1@tnstate.edu,"WcaG mutants macerated less tissue of celery petioles and carrot root discs in comparison with the parental strain, but did not affect the survival and multiplication ability of the pathogen.",R Islam 2019,2019,1 gene,Islam-2019-The Gene Encoding NAD-Dependent Epi,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14280,PHI:9305,UniProt,D4I307,GenBank,CBA23647,,,CFPB1430,argD,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,acetylornithine/succinyldiaminopimelate aminotransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14281,PHI:9306,UniProt,D4HYB2,GenBank,CBA21987,,,CFPB1430,guaB,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,inosine-5'-monophosphate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14282,PHI:9307,UniProt,D4I0W8,GenBank,CBA20393,,,CFPB1430,pyrC,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,dihydroorotase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14283,PHI:9308,UniProt,D4I4L2,GenBank,CBA24212,,,CFPB1430,glmS,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,glucosamine-fructose-6-phosphateaminotransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14284,PHI:9309,UniProt,D4HUC7,GenBank,CBA19050,,,CFPB1430,pfkA,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,ATP-dependent 6-phosphofructokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14285,PHI:9310,UniProt,D4I2T0,GenBank,CBA23505,,,CFPB1430,pgi,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,glucose-6-phosphate isomerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14286,PHI:9311,UniProt,D4HXP5,GenBank,CBA21825,,,CFPB1430,ptsH,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,phosphocarrier protein HPr,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14287,PHI:9312,UniProt,D4HXP6,GenBank,CBA21827,,,CFPB1430,ptsI,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,phosphoenolpyruvate-protein phosphotransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14288,PHI:9313,UniProt,D4I2T4,GenBank,CBA23513,,,CFPB1430,metA,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,homoserine O-succinyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14289,PHI:9314,UniProt,D4HUF7,GenBank,CBA19080,,,CFPB1430,metB,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,cystathionine gamma-synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14290,PHI:9315,UniProt,D4HUM7,GenBank,CBA19150,,,CFPB1430,metE,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14291,PHI:9316,UniProt,D4HUG4,GenBank,CBA19087,,,CFPB1430,argG,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,argininosuccinate synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14292,PHI:9317,UniProt,D4HXG4,GenBank,CBA21663,,,CFPB1430,purF,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,amidophosphoribosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14293,PHI:9318,UniProt,D4HUI1,GenBank,CBA19104,,,CFPB1430,ilvA,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,threonine dehydratase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14294,PHI:9319,UniProt,D4I012,GenBank,CBA22649,,,CFPB1430,leuB,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,3-isopropylmalate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14295,PHI:9320,UniProt,D4HYF4,GenBank,CBA22070,,,CFPB1430,purL,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,phosphoribosylformylglycinamidine synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14296,PHI:9321,UniProt,D4I3E6,GenBank,CBA20869,,,CFPB1430,trpB,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,tryptophan synthase beta chain,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14297,PHI:9322,UniProt,D4HUG1,GenBank,CBA19084,,,CFPB1430,ppc,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit; shoot,phosphoenolpyruvate carboxylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14298,PHI:9323,UniProt,D4HWM2,GenBank,CBA19698,,,CFPB1430,cysI3,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit; shoot,sulfite reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14299,PHI:9324,UniProt,D4HW76,GenBank,CBA21303,,,CFPB1430,hisA,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'-phosphoribosyl)-4-imidazolecarboxamide isomerase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14300,PHI:9325,UniProt,D4HUG0,GenBank,CBA19083,,,CFPB1430,metF,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,methylenetetrahydrofolate reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14301,PHI:9326,UniProt,D4HUM6,GenBank,CBA19149,,,CFPB1430,metR,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,HTH-type transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14302,PHI:9327,UniProt,D4HYW4,GenBank,CBA20089,,,CFPB1430,asnB,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,fruit,asparagine synthase B,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14303,PHI:9324,UniProt,D4HW76,GenBank,CBA21303,,,CFPB1430,hisA,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'-phosphoribosyl)-4-imidazolecarboxamide isomerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14304,PHI:9328,UniProt,D4I0H1,GenBank,CBA22700,,,CFPB1430,carA,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,carbamoyl-phosphate synthase small chain,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14305,PHI:9319,UniProt,D4I012,GenBank,CBA22649,,,CFPB1430,leuB,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,3-isopropylmalate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14306,PHI:9329,UniProt,D4I013,GenBank,CBA22651,,,CFPB1430,leuC,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,3-isopropylmalate dehydratase large subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14307,PHI:9315,UniProt,D4HUM7,GenBank,CBA19150,,,CFPB1430,metE,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14308,PHI:9323,UniProt,D4HWM2,GenBank,CBA19698,,,CFPB1430,cysI3,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,sulfite reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14309,PHI:9324,UniProt,D4HW76,GenBank,CBA21303,,,CFPB1430,hisA,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'-phosphoribosyl)-4-imidazolecarboxamide isomerase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14310,PHI:9305,UniProt,D4I307,GenBank,CBA23647,,,CFPB1430,argD,,,,,,,552,Erwinia amylovora,,HKN06P1,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,acetylornithine/succinyldiaminopimelate aminotransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31152019,PubMed,10.1128/AEM.00935-19,Appl Environ Microbiol. 2019 Jul 18;85(15),twm4@psu.edu,"On detached apple fruitlets, mutants defective in arginine, guanine, hexosamine, isoleucine/valine, leucine, lysine, proline, purine, pyrimidine, sorbitol, threonine, tryptophan, and glucose metabolism had reduced virulence compared to wild-type, while mutants defective in asparagine, cysteine, glutamic acid, histidine, and serine biosynthesis were as virulent as the wild-type.",S M Klee 2019,2019,25 genes,Klee-2019-Erwinia amylovora auxotrophic mutant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14311,PHI:9330,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,rop18,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),SF268 cell line,,,glioblastoma cell line,rhoptry kinase family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31164145,PubMed,10.1186/s13071-019-3529-1,Parasit Vectors. 2019 Jun 4;12(1):284,floriapeng@hotmail.com,"TgROP18 inhibited ATP-induced apoptosis of SF268 with P2X1 expression, but had no effect on RAW264.7 or THP-1 cells without detectable P2X1 expression.",L J Zhou 2019,2019,1 gene,Zhou-2019-Toxoplasma gondii ROP18 inhibits hum,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14312,PHI:9330,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,rop18,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte; macrophage,rhoptry kinase family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31164145,PubMed,10.1186/s13071-019-3529-1,Parasit Vectors. 2019 Jun 4;12(1):284,floriapeng@hotmail.com,"TgROP18 inhibited ATP-induced apoptosis of SF268 with P2X1 expression, but had no effect on RAW264.7 or THP-1 cells without detectable P2X1 expression.",L J Zhou 2019,2019,1 gene,Zhou-2019-Toxoplasma gondii ROP18 inhibits hum,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14313,PHI:9330,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,rop18,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,rhoptry kinase family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31164145,PubMed,10.1186/s13071-019-3529-1,Parasit Vectors. 2019 Jun 4;12(1):284,floriapeng@hotmail.com,"TgROP18 inhibited ATP-induced apoptosis of SF268 with P2X1 expression, but had no effect on RAW264.7 or THP-1 cells without detectable P2X1 expression.",L J Zhou 2019,2019,1 gene,Zhou-2019-Toxoplasma gondii ROP18 inhibits hum,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14314,PHI:9330,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,rop18,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9534,Chlorocebus aethiops (related: grivet),COS7 cell line,,,COS-7 cell,rhoptry kinase family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; other evidence: transgenic,,,YVS,31164145,PubMed,10.1186/s13071-019-3529-1,Parasit Vectors. 2019 Jun 4;12(1):284,floriapeng@hotmail.com,"TgROP18 interacted with P2X1, and overexpression of ROP18 in COS7 cells significantly inhibited cell apoptosis mediated by P2X1.",L J Zhou 2019,2019,1 gene,Zhou-2019-Toxoplasma gondii ROP18 inhibits hum,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14315,PHI:9331,UniProt,D2TKD7,GenBank,CBG89706,,,ICC168,espF,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-22<-/->),,,colonic epithelial cell; liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31251784,PubMed,10.1371/journal.ppat.1007898,PLoS Pathog. 2019 Jun 28;15(6):e1007898,fwan1@jhu.edu,Chromosomal deletion of espF in CR recapitulated the avirulent phenotype without impacting colonization and proliferation of CR.,X Xia 2019,2019,5 genes,Xia-2019-EspF is crucial for Citrobacter roden,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14316,PHI:9332,UniProt,D2TKF5,GenBank,CBG89725,,,ICC168,escN,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-22<-/->),,,colon; liver; spleen,T3SS translocator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,31251784,PubMed,10.1371/journal.ppat.1007898,PLoS Pathog. 2019 Jun 28;15(6):e1007898,fwan1@jhu.edu,The escN-interrupted mutant CR failed to colonize in IL22-/-mice.,X Xia 2019,2019,5 genes,Xia-2019-EspF is crucial for Citrobacter roden,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14317,PHI:9333,UniProt,D2TKD5,GenBank,CBG89704,,,ICC168,espG,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-22<-/->),,,colon; liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,31251784,PubMed,10.1371/journal.ppat.1007898,PLoS Pathog. 2019 Jun 28;15(6):e1007898,fwan1@jhu.edu,Chromosomal deletion of other known TJ-damaging effector genes espG and map failed to impede CR virulence in Il22-/mice.,X Xia 2019,2019,5 genes,Xia-2019-EspF is crucial for Citrobacter roden,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14318,PHI:9334,UniProt,D2TI55,GenBank,CBG86951,,,ICC168,map,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-22<-/->),,,colon; liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,31251784,PubMed,10.1371/journal.ppat.1007898,PLoS Pathog. 2019 Jun 28;15(6):e1007898,fwan1@jhu.edu,Chromosomal deletion of other known TJ-damaging effector genes espG and map failed to impede CR virulence in Il22-/mice.,X Xia 2019,2019,5 genes,Xia-2019-EspF is crucial for Citrobacter roden,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14319,PHI:9335,UniProt,Q6T6T6,GenBank,AAR84051,,,DBS100,nleA,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (IL-22<-/->),,,colon; liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,31251784,PubMed,10.1371/journal.ppat.1007898,PLoS Pathog. 2019 Jun 28;15(6):e1007898,fwan1@jhu.edu,"The fecal CFUs of ΔnleA CR were dramatically attenuated compared to other strains, indicating a marked defect in CR colonization and proliferation in vivo.",X Xia 2019,2019,5 genes,Xia-2019-EspF is crucial for Citrobacter roden,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14320,PHI:9336,,no data found,GenBank,AEX80148,,,HC04,CDHC04_0155,,,,,,,1717,Corynebacterium diphtheriae,698970,HC04,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,putative ribosome-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14321,PHI:9336,,no data found,GenBank,AEX80148,,,HC04,CDHC04_0155,,,,,,,1717,Corynebacterium diphtheriae,698970,HC04,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,putative ribosome-binding protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14322,PHI:9337,,no data found,GenBank,AEG80717,,,809,CULC809_00177,,,,,,,65058,Corynebacterium ulcerans,,809,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,putative ribosome-binding protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14323,PHI:9336,,no data found,GenBank,AEX80148,,,HC04,CDHC04_0155,,,,,,,1717,Corynebacterium diphtheriae,698970,HC04,diphtheria,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative ribosome-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14324,PHI:9336,,no data found,GenBank,AEX80148,,,HC04,CDHC04_0155,,,,,,,1717,Corynebacterium diphtheriae,698970,HC04,diphtheria,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative ribosome-binding protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14325,PHI:9337,,no data found,GenBank,AEG80717,,,809,CULC809_00177,,,,,,,65058,Corynebacterium ulcerans,,809,diphtheria,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative ribosome-binding protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14326,PHI:9336,,no data found,GenBank,AEX80148,,,HC04,CDHC04_0155,,,,,,,1717,Corynebacterium diphtheriae,698970,HC04,diphtheria,primates,9606,Homo sapiens (related: human),Detroit 562 cell line,,,hypopharyngeal carcinoma cell line,putative ribosome-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14327,PHI:9336,,no data found,GenBank,AEX80148,,,HC04,CDHC04_0155,,,,,,,1717,Corynebacterium diphtheriae,698970,HC04,diphtheria,primates,9606,Homo sapiens (related: human),Detroit 562 cell line,,,hypopharyngeal carcinoma cell line,putative ribosome-binding protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14328,PHI:9337,,no data found,GenBank,AEG80717,,,809,CULC809_00177,,,,,,,65058,Corynebacterium ulcerans,,809,diphtheria,primates,9606,Homo sapiens (related: human),Detroit 562 cell line,,,hypopharyngeal carcinoma cell line,putative ribosome-binding protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14329,PHI:9336,,no data found,GenBank,AEX80148,,,HC04,CDHC04_0155,,,,,,,1717,Corynebacterium diphtheriae,698970,HC04,diphtheria,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,putative ribosome-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14330,PHI:9336,,no data found,GenBank,AEX80148,,,HC04,CDHC04_0155,,,,,,,1717,Corynebacterium diphtheriae,698970,HC04,diphtheria,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,putative ribosome-binding protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14331,PHI:9337,,no data found,GenBank,AEG80717,,,809,CULC809_00177,,,,,,,65058,Corynebacterium ulcerans,,809,diphtheria,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,putative ribosome-binding protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31162026,PubMed,10.1099/mic.0.000820,Microbiology. 2019 Jun 4,andreas.burkovski@fau.de,Corynebacterial Rbps were cytotoxic and were involved in the break-down of transepithelial resistance of epithelial cell monolayers.,D Weerasekera 2019,2019,2 genes,Weerasekera-2019-Beyond diphtheria toxin_ cyto,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14332,PHI:9338,UniProt,A4VY17,GenBank,ABP91006,,,05ZYH33,pdh,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen; kidney; lung,pyruvate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31232165,PubMed,10.1080/21505594.2019.1631661,Virulence. 2019 Dec;10(1):588-599,wangyocean@163.com,"The ability to adhere to and invade PK15 cells, biofilm formation, survival rate in RAW264.7 macrophages, distribution of viable bacteria in the blood and organs of mice and stress resistance of Δpdh were significantly reduced.",Y Wang 2019,2019,1 gene,Wang-2019-pdh modulate virulence through reduc,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14333,PHI:9338,UniProt,A4VY17,GenBank,ABP91006,,,05ZYH33,pdh,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,pyruvate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31232165,PubMed,10.1080/21505594.2019.1631661,Virulence. 2019 Dec;10(1):588-599,wangyocean@163.com,"The ability to adhere to and invade PK15 cells, biofilm formation, survival rate in RAW264.7 macrophages, distribution of viable bacteria in the blood and organs of mice and stress resistance of Δpdh were significantly reduced.",Y Wang 2019,2019,1 gene,Wang-2019-pdh modulate virulence through reduc,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14334,PHI:9338,UniProt,A4VY17,GenBank,ABP91006,,,05ZYH33,pdh,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),PK-15 cell line,,,kidney cell line,pyruvate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31232165,PubMed,10.1080/21505594.2019.1631661,Virulence. 2019 Dec;10(1):588-599,wangyocean@163.com,"The ability to adhere to and invade PK15 cells, biofilm formation, survival rate in RAW264.7 macrophages, distribution of viable bacteria in the blood and organs of mice and stress resistance of Δpdh were significantly reduced.",Y Wang 2019,2019,1 gene,Wang-2019-pdh modulate virulence through reduc,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14335,PHI:9339,UniProt,D4I076,GenBank,CBA20283,,,CFPB1430,lrp,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,leucine-responsive regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"Lrp had no effect on type III secretion, as loss of lrp in wild-type or ΔarcZ mutant strains did not affect the hypersensitive response in nonhost tobacco.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14336,PHI:9340,,no data found,,,,,,arcZ,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"Lrp had no effect on type III secretion, as loss of lrp in wild-type or ΔarcZ mutant strains did not affect the hypersensitive response in nonhost tobacco.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14337,PHI:9339,UniProt,D4I076,GenBank,CBA20283,,,CFPB1430,lrp,,,,,,PHI:9340,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,leucine-responsive regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"Lrp had no effect on type III secretion, as loss of lrp in wild-type or ΔarcZ mutant strains did not affect the hypersensitive response in nonhost tobacco.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14338,PHI:9340,,no data found,,,,,,arcZ,,,,,,PHI:9339,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,small RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"The reduced virulence of the Δlrp mutant in the apple shoot model of infection but not in the immature pear infection model indicated that this cascade, with both Lrp and ArcZ, was required for proper regulation of E. amylovora behaviors during host infection.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14339,PHI:9339,UniProt,D4I076,GenBank,CBA20283,,,CFPB1430,lrp,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,leucine-responsive regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"The reduced virulence of the Δlrp mutant in the apple shoot model of infection but not in the immature pear infection model indicated that this cascade, with both Lrp and ArcZ, was required for proper regulation of E. amylovora behaviors during host infection.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14340,PHI:9340,,no data found,,,,,,arcZ,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"The reduced virulence of the Δlrp mutant in the apple shoot model of infection but not in the immature pear infection model indicated that this cascade, with both Lrp and ArcZ, was required for proper regulation of E. amylovora behaviors during host infection.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14341,PHI:9339,UniProt,D4I076,GenBank,CBA20283,,,CFPB1430,lrp,,,,,,PHI:9340,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,leucine-responsive regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"The reduced virulence of the Δlrp mutant in the apple shoot model of infection but not in the immature pear infection model indicated that this cascade, with both Lrp and ArcZ, was required for proper regulation of E. amylovora behaviors during host infection.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14342,PHI:9340,,no data found,,,,,,arcZ,,,,,,PHI:9339,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,small RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"The reduced virulence of the Δlrp mutant in the apple shoot model of infection but not in the immature pear infection model indicated that this cascade, with both Lrp and ArcZ, was required for proper regulation of E. amylovora behaviors during host infection.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14343,PHI:9339,UniProt,D4I076,GenBank,CBA20283,,,CFPB1430,lrp,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,leucine-responsive regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"The reduced virulence of the Δlrp mutant in the apple shoot model of infection but not in the immature pear infection model indicated that this cascade, with both Lrp and ArcZ, was required for proper regulation of E. amylovora behaviors during host infection.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14344,PHI:9340,,no data found,,,,,,arcZ,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"The reduced virulence of the Δlrp mutant in the apple shoot model of infection but not in the immature pear infection model indicated that this cascade, with both Lrp and ArcZ, was required for proper regulation of E. amylovora behaviors during host infection.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14345,PHI:9339,UniProt,D4I076,GenBank,CBA20283,,,CFPB1430,lrp,,,,,,PHI:9340,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,leucine-responsive regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"The reduced virulence of the Δlrp mutant in the apple shoot model of infection but not in the immature pear infection model indicated that this cascade, with both Lrp and ArcZ, was required for proper regulation of E. amylovora behaviors during host infection.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14346,PHI:9340,,no data found,,,,,,arcZ,,,,,,PHI:9339,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31138749,PubMed,10.1128/mBio.00757-19,MBio. 2019 May 28;10(3),sundin@msu.edu,"The reduced virulence of the Δlrp mutant in the apple shoot model of infection but not in the immature pear infection model indicated that this cascade, with both Lrp and ArcZ, was required for proper regulation of E. amylovora behaviors during host infection.",J K Schachterle 2019,2019,2 genes,Schachterle-2019-The Leucine-Responsive Regula,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14347,PHI:9341,UniProt,A0A059XKS9,GenBank,AIA26429,,,RH,crt,,,,,,,5811,Toxoplasma gondii,383379,RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,chloroquine resistance transporter,,,,reduced virulence,,,,,,,,wild type,,no,zaprinast,zaprinast: CAS:37762-06-4,,,,,gene deletion: full; gene complementation,,,YVS,31170269,PubMed,10.1371/journal.ppat.1007775,PLoS Pathog. 2019 Jun 6;15(6):e1007775,zdou@clemson.edu,Toxoplasma parasites required the TgCRT protein for optimal invasion and acute virulence but not for replication and egress.,L B Thornton 2019,2019,1 gene,Thornton-2019-An ortholog of Plasmodium falcip,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14348,PHI:9341,UniProt,A0A059XKS9,GenBank,AIA26429,,,RH,crt,,,,,,,5811,Toxoplasma gondii,383379,RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,chloroquine resistance transporter,,,,reduced virulence,,,,,,,,wild type,,no,zaprinast,zaprinast: CAS:37762-06-4,,,,,gene deletion: full; gene complementation,,,YVS,31170269,PubMed,10.1371/journal.ppat.1007775,PLoS Pathog. 2019 Jun 6;15(6):e1007775,zdou@clemson.edu,The Δcrt mutant showed reduction in host cell attachment and had slower invasion kinetics compared to WT.,L B Thornton 2019,2019,1 gene,Thornton-2019-An ortholog of Plasmodium falcip,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14349,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB, but neither RipP1 nor RipAA, acted as a major Avr effector that restricted the host range of RS1002 to N. benthamiana.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14350,PHI:9343,UniProt,Q700W1,,,,,,ripP1 (PopP1),,,,,,PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB, but neither RipP1 nor RipAA, acted as a major Avr effector that restricted the host range of RS1002 to N. benthamiana.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14351,PHI:9344,UniProt,A0A0S4UFN8,GenBank,CEJ18476,,,IPO1609,ripAA,,,,,,PHI:9343,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB, but neither RipP1 nor RipAA, acted as a major Avr effector that restricted the host range of RS1002 to N. benthamiana.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14352,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,PHI:9343,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,RipP1 and RipAA acted as minor Avr effectors that reduced bacterial virulence in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14353,PHI:9343,UniProt,Q700W1,,,,,,ripP1 (PopP1),,,,,,PHI:9342,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,RipP1 and RipAA acted as minor Avr effectors that reduced bacterial virulence in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14354,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,RipP1 and RipAA acted as minor Avr effectors that reduced bacterial virulence in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14355,PHI:9344,UniProt,A0A0S4UFN8,GenBank,CEJ18476,,,IPO1609,ripAA,,,,,,PHI:9342,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,RipP1 and RipAA acted as minor Avr effectors that reduced bacterial virulence in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14356,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,PHI:9343; PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,RipP1 and RipAA acted as minor Avr effectors that reduced bacterial virulence in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14357,PHI:9343,UniProt,Q700W1,,,,,,ripP1 (PopP1),,,,,,PHI:9342; PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,RipP1 and RipAA acted as minor Avr effectors that reduced bacterial virulence in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14358,PHI:9344,UniProt,A0A0S4UFN8,GenBank,CEJ18476,,,IPO1609,ripAA,,,,,,PHI:9342; PHI:9343,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,RipP1 and RipAA acted as minor Avr effectors that reduced bacterial virulence in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14359,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,,305,Ralstonia solanacearum,,RS1000,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,The C-terminal-truncated RipB mutants did not act as an Avr effector in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14360,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,,305,Ralstonia solanacearum,,BK1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,The C-terminal-truncated RipB mutants did not act as an Avr effector in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14361,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14362,PHI:9343,UniProt,Q700W1,,,,,,ripP1 (PopP1),,,,,,PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14363,PHI:9344,UniProt,A0A0S4UFN8,GenBank,CEJ18476,,,IPO1609,ripAA,,,,,,PHI:9343,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14364,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,PHI:9343; PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14365,PHI:9343,UniProt,Q700W1,,,,,,ripP1 (PopP1),,,,,,PHI:9342; PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14366,PHI:9344,UniProt,A0A0S4UFN8,GenBank,CEJ18476,,,IPO1609,ripAA,,,,,,PHI:9342; PHI:9343,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14367,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4091,Nicotiana otophora (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14368,PHI:9343,UniProt,Q700W1,,,,,,ripP1 (PopP1),,,,,,PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4091,Nicotiana otophora (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14369,PHI:9344,UniProt,A0A0S4UFN8,GenBank,CEJ18476,,,IPO1609,ripAA,,,,,,PHI:9343,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4091,Nicotiana otophora (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14370,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,PHI:9343; PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4091,Nicotiana otophora (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14371,PHI:9343,UniProt,Q700W1,,,,,,ripP1 (PopP1),,,,,,PHI:9342; PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4091,Nicotiana otophora (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14372,PHI:9344,UniProt,A0A0S4UFN8,GenBank,CEJ18476,,,IPO1609,ripAA,,,,,,PHI:9342; PHI:9343,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4091,Nicotiana otophora (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14373,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4096,Nicotiana sylvestris (related: wood tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14374,PHI:9343,UniProt,Q700W1,,,,,,ripP1 (PopP1),,,,,,PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4096,Nicotiana sylvestris (related: wood tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14375,PHI:9344,UniProt,A0A0S4UFN8,GenBank,CEJ18476,,,IPO1609,ripAA,,,,,,PHI:9343,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4096,Nicotiana sylvestris (related: wood tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14376,PHI:9342,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,ripB,,,,,,PHI:9343; PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4096,Nicotiana sylvestris (related: wood tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14377,PHI:9343,UniProt,Q700W1,,,,,,ripP1 (PopP1),,,,,,PHI:9342; PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4096,Nicotiana sylvestris (related: wood tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14378,PHI:9344,UniProt,A0A0S4UFN8,GenBank,CEJ18476,,,IPO1609,ripAA,,,,,,PHI:9342; PHI:9343,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4096,Nicotiana sylvestris (related: wood tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,"RipB was recognized as an Avr effector in N. tabacum and N. otophora, but not in N. sylvestris.",M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14379,PHI:9345,UniProt,F6G5M5,GenBank,AEG70452,,,Po82,roq1,,,,,,PHI:9343; PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,nucleotide-binding leucine-rich repeat (NLR) protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,Roq1 was involved in the recognition of RipB in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14380,PHI:9343,UniProt,Q700W1,,,,,,ripP1 (PopP1),,,,,,PHI:9345; PHI:9344,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,Roq1 was involved in the recognition of RipB in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14381,PHI:9344,UniProt,A0A0S4UFN8,GenBank,CEJ18476,,,IPO1609,ripAA,,,,,,PHI:9345; PHI:9343,305,Ralstonia solanacearum,,RS1002,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31218811,PubMed,10.1111/mpp.12824,Mol Plant Pathol. 2019 Jun 20,mukaihara@bio-ribs.com,Roq1 was involved in the recognition of RipB in N. benthamiana.,M Nakano 2019,2019,4 genes,Nakano-2019-The type III effector RipB from Ra,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14382,PHI:9346,UniProt,A0A411HAI4,GenBank,QBB20986,,,QT598,tagB,,,,,,,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease tandem autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14383,PHI:9347,UniProt,A0A411HAJ2,GenBank,QBB20996,,,QT598,tagC,,,,,,,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease tandem autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14384,PHI:9348,,no data found,GenBank,QDB64255,,,QT598,sha,,,,,,,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease hemaglutinin autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14385,PHI:9349,,no data found,GenBank,QDX43250,,,BCE049,vat,,,,,,,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14386,PHI:9350,,no data found,GenBank,QDB64251,,,QT598,tsh,,,,,,,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14387,PHI:9346,UniProt,A0A411HAI4,GenBank,QBB20986,,,QT598,tagB,,,,,,PHI:9347,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease tandem autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14388,PHI:9347,UniProt,A0A411HAJ2,GenBank,QBB20996,,,QT598,tagC,,,,,,PHI:9346,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease tandem autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14389,PHI:9346,UniProt,A0A411HAI4,GenBank,QBB20986,,,QT598,tagB,,,,,,PHI:9347; PHI:9348; PHI:9349; PHI:9350,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease tandem autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14390,PHI:9347,UniProt,A0A411HAJ2,GenBank,QBB20996,,,QT598,tagC,,,,,,PHI:9346; PHI:9348; PHI:9349; PHI:9350,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease tandem autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14391,PHI:9348,,no data found,GenBank,QDB64255,,,QT598,sha,,,,,,PHI:9346; PHI:9347; PHI:9349; PHI:9350,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease hemaglutinin autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14392,PHI:9349,,no data found,GenBank,QDX43250,,,BCE049,vat,,,,,,PHI:9346; PHI:9347; PHI:9348; PHI:9350,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14393,PHI:9350,,no data found,GenBank,QDB64251,,,QT598,tsh,,,,,,PHI:9346; PHI:9347; PHI:9348; PHI:9349,562,Escherichia coli,,QCT598,neonatal meningitis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder,serine protease autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14394,PHI:9346,UniProt,A0A411HAI4,GenBank,QBB20986,,,QT598,tagB,,,,,,PHI:9347; PHI:9348; PHI:9349; PHI:9350,562,Escherichia coli,,QCT598,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; bladder,serine protease tandem autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14395,PHI:9347,UniProt,A0A411HAJ2,GenBank,QBB20996,,,QT598,tagC,,,,,,PHI:9346; PHI:9348; PHI:9349; PHI:9350,562,Escherichia coli,,QCT598,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; bladder,serine protease tandem autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14396,PHI:9348,,no data found,GenBank,QDB64255,,,QT598,sha,,,,,,PHI:9346; PHI:9347; PHI:9349; PHI:9350,562,Escherichia coli,,QCT598,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; bladder,serine protease hemaglutinin autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14397,PHI:9349,,no data found,GenBank,QDX43250,,,BCE049,vat,,,,,,PHI:9346; PHI:9347; PHI:9348; PHI:9350,562,Escherichia coli,,QCT598,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; bladder,serine protease autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14398,PHI:9350,,no data found,GenBank,QDB64251,,,QT598,tsh,,,,,,PHI:9346; PHI:9347; PHI:9348; PHI:9349,562,Escherichia coli,,QCT598,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; bladder,serine protease autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14399,PHI:9346,UniProt,A0A411HAI4,GenBank,QBB20986,,,QT598,tagB,,,,,,PHI:9347,562,Escherichia coli,,QCT598,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; bladder,serine protease tandem autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14400,PHI:9347,UniProt,A0A411HAJ2,GenBank,QBB20996,,,QT598,tagC,,,,,,PHI:9346,562,Escherichia coli,,QCT598,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; bladder,serine protease tandem autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14401,PHI:9348,,no data found,GenBank,QDB64255,,,QT598,sha,,,,,,,562,Escherichia coli,,QCT598,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; bladder,serine protease hemaglutinin autotransporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31198092,PubMed,10.1080/21505594.2019.1624102,Virulence. 2019 Dec;10(1):568-587,charles.dozois@inrs.ca,"Deletion of all 5 SPATEs, significantly reduced competitive colonization of the kidney supporting a cumulative role of SPATEs for QT598 in the mouse UTI model.",H Habouria 2019,2019,5 genes,Habouria-2019-Three new serine-protease autotr,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14402,PHI:9351,UniProt,A0A2T6IKH7,GenBank,PUA85834,,,TgCATBr9,pyk1,,insertion of ATc-regulatable promoter (pSAG1-TetO7) along with the pyrimethamine selection marker (dihydrofolate reductase [DHFR]) immediately upstream of the coding sequence of PYK1,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,peritoneal fluid,pyruvate kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: downregulation,,,YVS,31186321,PubMed,10.1128/mBio.00898-19,MBio. 2019 Jun 11;10(3),shenbang@mail.hzau.edu.cn,"Conditional depletion of PYK1 resulted in global alteration of carbon metabolism, amylopectin accumulation, and reduced cellular ATP, leading to severe growth impairment.",N Xia 2019,2019,2 genes,Xia-2019-Pyruvate Homeostasis as a Determinant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14403,PHI:9352,,no data found,,,,,,pyk2,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,peritoneal fluid,pyruvate kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31186321,PubMed,10.1128/mBio.00898-19,MBio. 2019 Jun 11;10(3),shenbang@mail.hzau.edu.cn,"PYK2 located in the apicoplast was not required for parasite survival, growth, or virulence.",N Xia 2019,2019,2 genes,Xia-2019-Pyruvate Homeostasis as a Determinant,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14404,PHI:9353,UniProt,G4N5B0,GenBank,EHA52967,,,70-15,leu2A (MGG_05223),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,3-isopropylmalate dehydrogenase,,,leucine biosynthesis,reduced virulence,,yes,yes,yes,,reduced,wild type,reduced; aberrant,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14405,PHI:9354,UniProt,G4NIK0,GenBank,EHA48060,,,70-15,leu2B (MGG_09813),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,3-isopropylmalate dehydrogenase,,,,unaffected pathogenicity,,no,no,no,,wild type,wild type,wild type,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14406,PHI:9353,UniProt,G4N5B0,GenBank,EHA52967,,,70-15,leu2A (MGG_05223),chromosome 3,,,,,PHI:9354,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,3-isopropylmalate dehydrogenase,,,leucine biosynthesis,reduced virulence,,yes,yes,yes,,reduced,wild type,reduced; aberrant,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14407,PHI:9354,UniProt,G4NIK0,GenBank,EHA48060,,,70-15,leu2B (MGG_09813),chromosome 6,,,,,PHI:9353,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,3-isopropylmalate dehydrogenase,,,leucine biosynthesis,reduced virulence,,yes,yes,yes,,reduced,wild type,reduced; aberrant,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14408,PHI:9355,UniProt,G4MTG9,GenBank,EHA54720,,,70-15,leu1 (MGG_01553),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,3-isopropylmalate dehydratase,,,leucine biosynthesis,reduced virulence,,yes,yes,,,reduced,wild type,reduced; aberrant,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14409,PHI:9356,UniProt,G4N6T3,GenBank,EHA49900,,,70-15,leu4 (MGG_13485),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,2-isopropylmalate synthase,,,leucine biosynthesis,reduced virulence,,yes,yes,,,reduced,wild type,reduced; aberrant,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14410,PHI:9353,UniProt,G4N5B0,GenBank,EHA52967,,,70-15,leu2A (MGG_05223),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf; root,3-isopropylmalate dehydrogenase,,,leucine biosynthesis,reduced virulence,,yes,yes,yes,,reduced,wild type,reduced; aberrant,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14411,PHI:9354,UniProt,G4NIK0,GenBank,EHA48060,,,70-15,leu2B (MGG_09813),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf; root,3-isopropylmalate dehydrogenase,,,,unaffected pathogenicity,,no,no,no,,wild type,wild type,wild type,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14412,PHI:9353,UniProt,G4N5B0,GenBank,EHA52967,,,70-15,leu2A (MGG_05223),chromosome 3,,,,,PHI:9354,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf; root,3-isopropylmalate dehydrogenase,,,leucine biosynthesis,reduced virulence,,yes,yes,yes,,reduced,wild type,reduced; aberrant,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14413,PHI:9354,UniProt,G4NIK0,GenBank,EHA48060,,,70-15,leu2B (MGG_09813),chromosome 6,,,,,PHI:9353,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf; root,3-isopropylmalate dehydrogenase,,,leucine biosynthesis,reduced virulence,,yes,yes,yes,,reduced,wild type,reduced; aberrant,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14414,PHI:9355,UniProt,G4MTG9,GenBank,EHA54720,,,70-15,leu1 (MGG_01553),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf; root,3-isopropylmalate dehydratase,,,leucine biosynthesis,reduced virulence,,yes,yes,,,reduced,wild type,reduced; aberrant,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14415,PHI:9356,UniProt,G4N6T3,GenBank,EHA49900,,,70-15,leu4 (MGG_13485),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf; root,2-isopropylmalate synthase,,,leucine biosynthesis,reduced virulence,,yes,yes,,,reduced,wild type,reduced; aberrant,,no,sorbitol; mannitol; NaCl; KCl; H2O2; SDS; Congo red,sorbitol: CHEBI:17924; mannitol: CHEBI:29864; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"Targeted gene deletion mutants of LEU1, LEU2A or LEU4 were leucine auxotrophs, and severely defective in pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14416,PHI:9357,UniProt,I1RYX6,GenBank,CEF83100,,,PH-1,Fgleu1 (FGSG_09589),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,3-isopropylmalate dehydratase,,,leucine biosynthesis,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"FgLEU1, FgLEU3 and FgLEU4 were essential for wheat head blight disease, suggesting that leucine biosynthesis in filamentous fungal pathogens may be a conserved factor for fungal pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14417,PHI:9358,UniProt,I1RB16,GenBank,XP_011316425,,,PH-1; NRRL 31084,Fgleu3 (FGSG_00719),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,Zn(2)-C6 fungal-type domain-containing protein,,,leucine biosynthesis,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"FgLEU1, FgLEU3 and FgLEU4 were essential for wheat head blight disease, suggesting that leucine biosynthesis in filamentous fungal pathogens may be a conserved factor for fungal pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14418,PHI:9359,UniProt,A0A098DUS9,GenBank,XP_011326252,,,PH-1; NRRL 31084,Fgleu4 (FGSG_12952),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,2-isopropylmalate synthase,,,leucine biosynthesis,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"FgLEU1, FgLEU3 and FgLEU4 were essential for wheat head blight disease, suggesting that leucine biosynthesis in filamentous fungal pathogens may be a conserved factor for fungal pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14419,PHI:9360,UniProt,I1RYQ4,GenBank,CEF83161,,,PH-1,Fgbat1/2 (FGSG_09512),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,branched-chain-amino-acid aminotransferase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31263943,PubMed,10.1007/s00294-019-01009-2,Curr Genet. 2019 Jul 1,zhywang@zju.edu.cn,"FgLEU1, FgLEU3 and FgLEU4 were essential for wheat head blight disease, suggesting that leucine biosynthesis in filamentous fungal pathogens may be a conserved factor for fungal pathogenicity.",Y Que 2019,2019,8 genes,Que-2019-Leucine biosynthesis is required for,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14420,PHI:9361,UniProt,Q5XE42,GenBank,AAT86321,,,MGAS10394,NADase,,,,,,,1314,Streptococcus pyogenes,,serotype M1 strain 854,necrotizing fasciitis; toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),B6 BMDM,,,bone marrow-derived macrophage,beta-NAD+-glycohydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31275321,PubMed,10.3389/fimmu.2019.01385,Front Immunol. 2019 Jun 18;10:1385,jenny_j.persson@med.lu.se,"Bacteria expressing a functional NADase evaded P2X7 activation, while infection with a NADase-deficient GAS strain led to a P2X7-mediated increase in IL-1β.",E Westerlund 2019,2019,1 gene,Westerlund-2019-The Secreted Virulence Factor,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14421,PHI:9361,UniProt,Q5XE42,GenBank,AAT86321,,,MGAS10394,NADase,,,,,,,1314,Streptococcus pyogenes,,serotype M1 strain 854,necrotizing fasciitis; toxic shock syndrome,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,beta-NAD+-glycohydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31275321,PubMed,10.3389/fimmu.2019.01385,Front Immunol. 2019 Jun 18;10:1385,jenny_j.persson@med.lu.se,"Bacteria expressing a functional NADase evaded P2X7 activation, while infection with a NADase-deficient GAS strain led to a P2X7-mediated increase in IL-1β.",E Westerlund 2019,2019,1 gene,Westerlund-2019-The Secreted Virulence Factor,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14422,PHI:9362,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,aminoguanidine,aminoguanidine: CHEBI:40618,,,,,gene deletion: full,,,YVS,31119110,PubMed,10.3389/fcimb.2019.00140,Front Cell Infect Microbiol. 2019 May 1;9:140,myamamoto@biken.osaka-u.ac.jp,"Co-culturing type II T. gondii infected THP-1 human monocytes with the brain cell lines (A172; glioblastoma, IMR-32; neuroblastoma, and T98G; glioblastoma) inhibited the IDO1-mediated anti-T. gondii response in a GRA15-dependent manner.",H Bando 2019,2019,1 gene,Bando-2019-Toxoplasma Effector GRA15-Dependent,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14423,PHI:9362,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),A-172 cell line,,,glioblastoma cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,aminoguanidine,aminoguanidine: CHEBI:40618,,,,,gene deletion: full,,,YVS,31119110,PubMed,10.3389/fcimb.2019.00140,Front Cell Infect Microbiol. 2019 May 1;9:140,myamamoto@biken.osaka-u.ac.jp,"Co-culturing type II T. gondii infected THP-1 human monocytes with the brain cell lines (A172; glioblastoma, IMR-32; neuroblastoma, and T98G; glioblastoma) inhibited the IDO1-mediated anti-T. gondii response in a GRA15-dependent manner.",H Bando 2019,2019,1 gene,Bando-2019-Toxoplasma Effector GRA15-Dependent,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14424,PHI:9362,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),IMR-32 cell line,,,neuroblastoma cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,aminoguanidine,aminoguanidine: CHEBI:40618,,,,,gene deletion: full,,,YVS,31119110,PubMed,10.3389/fcimb.2019.00140,Front Cell Infect Microbiol. 2019 May 1;9:140,myamamoto@biken.osaka-u.ac.jp,"Co-culturing type II T. gondii infected THP-1 human monocytes with the brain cell lines (A172; glioblastoma, IMR-32; neuroblastoma, and T98G; glioblastoma) inhibited the IDO1-mediated anti-T. gondii response in a GRA15-dependent manner.",H Bando 2019,2019,1 gene,Bando-2019-Toxoplasma Effector GRA15-Dependent,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14425,PHI:9362,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),T98G cell line,,,glioblastoma cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,aminoguanidine,aminoguanidine: CHEBI:40618,,,,,gene deletion: full,,,YVS,31119110,PubMed,10.3389/fcimb.2019.00140,Front Cell Infect Microbiol. 2019 May 1;9:140,myamamoto@biken.osaka-u.ac.jp,"Co-culturing type II T. gondii infected THP-1 human monocytes with the brain cell lines (A172; glioblastoma, IMR-32; neuroblastoma, and T98G; glioblastoma) inhibited the IDO1-mediated anti-T. gondii response in a GRA15-dependent manner.",H Bando 2019,2019,1 gene,Bando-2019-Toxoplasma Effector GRA15-Dependent,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14426,PHI:9363,UniProt,P0AE88,GenBank,AAC36868,,,L547,CpxR,,,,,,,562,Escherichia coli,,serotype O2:K1 strain DE719,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),,,,lung; liver; spleen,two-component regulatory system response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31126325,PubMed,10.1186/s13567-019-0658-7,Vet Res. 2019 May 24;50(1):40,yus@shvri.ac.cn,"Inactivation of cpxR led to significant defects in the interbacterial competition activity, invasion and survival of APEC in vitro and in vivo.",Z Yi 2019,2019,1 gene,Yi-2019-The CpxR regulates type VI secretion s,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14427,PHI:9363,UniProt,P0AE88,GenBank,AAC36868,,,L547,CpxR,,,,,,,562,Escherichia coli,,serotype O2:K1 strain DE719,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryonic fibroblast cell line,two-component regulatory system response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31126325,PubMed,10.1186/s13567-019-0658-7,Vet Res. 2019 May 24;50(1):40,yus@shvri.ac.cn,"Inactivation of cpxR led to significant defects in the interbacterial competition activity, invasion and survival of APEC in vitro and in vivo.",Z Yi 2019,2019,1 gene,Yi-2019-The CpxR regulates type VI secretion s,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14428,PHI:9364,UniProt,S7VZX5,GenBank,EPR60419,,,GT1,TGGT1 238950,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,glioblastoma cell,stearoyl-coenzyme A (CoA) desaturase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31139819,PubMed,10.1093/abbs/gmz040,Acta Biochim Biophys Sin (Shanghai). 2019 Jun 20;51(6):615-626,qunliu@cau.edu.cn,The growth in vitro and pathogenicity in mice of the mutants suggested that SCD might be dispensable for tachyzoite growth and proliferation.,P Hao 2019,2019,1 gene,Hao-2019-Identification and characterization o,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14429,PHI:9364,UniProt,S7VZX5,GenBank,EPR60419,,,GT1,TGGT1 238950,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,stearoyl-coenzyme A (CoA) desaturase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31139819,PubMed,10.1093/abbs/gmz040,Acta Biochim Biophys Sin (Shanghai). 2019 Jun 20;51(6):615-626,qunliu@cau.edu.cn,The growth in vitro and pathogenicity in mice of the mutants suggested that SCD might be dispensable for tachyzoite growth and proliferation.,P Hao 2019,2019,1 gene,Hao-2019-Identification and characterization o,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14430,PHI:9364,UniProt,S7VZX5,GenBank,EPR60419,,,GT1,TGGT1 238950,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,glioblastoma cell,stearoyl-coenzyme A (CoA) desaturase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31139819,PubMed,10.1093/abbs/gmz040,Acta Biochim Biophys Sin (Shanghai). 2019 Jun 20;51(6):615-626,qunliu@cau.edu.cn,"The SCD-overexpressing tachyzoites propagated slower than the parental strain, with a decreased invasion capability and weaker pathogenicity in mice.",P Hao 2019,2019,1 gene,Hao-2019-Identification and characterization o,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14431,PHI:9364,UniProt,S7VZX5,GenBank,EPR60419,,,GT1,TGGT1 238950,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,stearoyl-coenzyme A (CoA) desaturase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31139819,PubMed,10.1093/abbs/gmz040,Acta Biochim Biophys Sin (Shanghai). 2019 Jun 20;51(6):615-626,qunliu@cau.edu.cn,"The SCD-overexpressing tachyzoites propagated slower than the parental strain, with a decreased invasion capability and weaker pathogenicity in mice.",P Hao 2019,2019,1 gene,Hao-2019-Identification and characterization o,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14432,PHI:9365,UniProt,P0DJM0,GenBank,CAC20628,,,EGD,inlA,,premature stop codon (PMSC) mutation,,,,,1639,Listeria monocytogenes,169963,SHL006,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31198443,PubMed,10.1186/s13099-019-0307-8,Gut Pathog. 2019 Jun 10;11:30,jmeng@umd.edu,The PMSC mutations in inlA correlated with the inability of the L. monocytogenes isolates to invade Caco-2 cells.,X Su 2019,2019,1 gene,Su-2019-Characterization of internalin genes i,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14433,PHI:9365,UniProt,P0DJM0,GenBank,CAC20628,,,EGD,inlA,,premature stop codon (PMSC) mutation,,,,,1639,Listeria monocytogenes,169963,LM430,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31198443,PubMed,10.1186/s13099-019-0307-8,Gut Pathog. 2019 Jun 10;11:30,jmeng@umd.edu,The PMSC mutations in inlA correlated with the inability of the L. monocytogenes isolates to invade Caco-2 cells.,X Su 2019,2019,1 gene,Su-2019-Characterization of internalin genes i,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14434,PHI:9365,UniProt,P0DJM0,GenBank,CAC20628,,,EGD,inlA,,premature stop codon (PMSC) mutation,,,,,1639,Listeria monocytogenes,169963,LM440,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31198443,PubMed,10.1186/s13099-019-0307-8,Gut Pathog. 2019 Jun 10;11:30,jmeng@umd.edu,The PMSC mutations in inlA correlated with the inability of the L. monocytogenes isolates to invade Caco-2 cells.,X Su 2019,2019,1 gene,Su-2019-Characterization of internalin genes i,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14435,PHI:9365,UniProt,P0DJM0,GenBank,CAC20628,,,EGD,inlA,,premature stop codon (PMSC) mutation,,,,,1639,Listeria monocytogenes,169963,LM470,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31198443,PubMed,10.1186/s13099-019-0307-8,Gut Pathog. 2019 Jun 10;11:30,jmeng@umd.edu,The PMSC mutations in inlA correlated with the inability of the L. monocytogenes isolates to invade Caco-2 cells.,X Su 2019,2019,1 gene,Su-2019-Characterization of internalin genes i,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14436,PHI:9365,UniProt,P0DJM0,GenBank,CAC20628,,,EGD,inlA,,premature stop codon (PMSC) mutation,,,,,1639,Listeria monocytogenes,169963,SHL12-2,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31198443,PubMed,10.1186/s13099-019-0307-8,Gut Pathog. 2019 Jun 10;11:30,jmeng@umd.edu,The PMSC mutations in inlA correlated with the inability of the L. monocytogenes isolates to invade Caco-2 cells.,X Su 2019,2019,1 gene,Su-2019-Characterization of internalin genes i,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14437,PHI:9365,UniProt,P0DJM0,GenBank,CAC20628,,,EGD,inlA,,premature stop codon (PMSC) mutation,,,,,1639,Listeria monocytogenes,169963,SHL12-22,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31198443,PubMed,10.1186/s13099-019-0307-8,Gut Pathog. 2019 Jun 10;11:30,jmeng@umd.edu,The PMSC mutations in inlA correlated with the inability of the L. monocytogenes isolates to invade Caco-2 cells.,X Su 2019,2019,1 gene,Su-2019-Characterization of internalin genes i,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14438,PHI:9365,UniProt,P0DJM0,GenBank,CAC20628,,,EGD,inlA,,premature stop codon (PMSC) mutation,,,,,1639,Listeria monocytogenes,169963,SHL13-12,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31198443,PubMed,10.1186/s13099-019-0307-8,Gut Pathog. 2019 Jun 10;11:30,jmeng@umd.edu,The PMSC mutations in inlA correlated with the inability of the L. monocytogenes isolates to invade Caco-2 cells.,X Su 2019,2019,1 gene,Su-2019-Characterization of internalin genes i,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14439,PHI:9366,UniProt,P54292,GenBank,AAC44036,,,PAO1,RhlR,chromosome 1,RhlR Y64F W68F V133F triple mutant,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,quorum-sensing receptor,,,pyocyanin production,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31194839,PubMed,10.1371/journal.ppat.1007820,PLoS Pathog. 2019 Jun 13;15(6):e1007820,bbassler@princeton.edu,RhlR mutant exhibited wildtype biofilm formation and infection in a nematode animal model.,A R McCready 2019,2019,3 genes,McCready-2019-An autoinducer-independent RhlR,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14440,PHI:9367,UniProt,P54291,GenBank,AAA82725,,,DSM2659,rhlI,,,,,,PHI:9368,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative autoinducer synthetase,,,pyocyanin production,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31194839,PubMed,10.1371/journal.ppat.1007820,PLoS Pathog. 2019 Jun 13;15(6):e1007820,bbassler@princeton.edu,"The rhlR* ΔrhlI ΔpqsE mutant P. aeruginosa strain killed 75% of the C.elegans, however, less than the wildtype, by contrast, the ΔrhlI ΔpqsE strain was highly attenuated, killing only 2% of the nematodes.",A R McCready 2019,2019,3 genes,McCready-2019-An autoinducer-independent RhlR,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14441,PHI:9368,UniProt,P20581,GenBank,AAA88447,,,PAO1,pqsE,,,,,,PHI:9367,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,2-aminobenzoylacetyl-CoA thioesterase,,,pyocyanin production,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31194839,PubMed,10.1371/journal.ppat.1007820,PLoS Pathog. 2019 Jun 13;15(6):e1007820,bbassler@princeton.edu,"The rhlR* ΔrhlI ΔpqsE mutant P. aeruginosa strain killed 75% of the C.elegans, however, less than the wildtype, by contrast, the ΔrhlI ΔpqsE strain was highly attenuated, killing only 2% of the nematodes.",A R McCready 2019,2019,3 genes,McCready-2019-An autoinducer-independent RhlR,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14442,PHI:9366,UniProt,P54292,GenBank,AAC44036,,,PAO1,RhlR,chromosome 1,RhlR Y64F W68F V133F triple mutant,,,,PHI:9367; PHI:9368,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,quorum-sensing receptor,,,pyocyanin production,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31194839,PubMed,10.1371/journal.ppat.1007820,PLoS Pathog. 2019 Jun 13;15(6):e1007820,bbassler@princeton.edu,"The rhlR* ΔrhlI ΔpqsE mutant P. aeruginosa strain killed 75% of the C.elegans, however, less than the wildtype, by contrast, the ΔrhlI ΔpqsE strain was highly attenuated, killing only 2% of the nematodes.",A R McCready 2019,2019,3 genes,McCready-2019-An autoinducer-independent RhlR,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14443,PHI:9367,UniProt,P54291,GenBank,AAA82725,,,DSM2659,rhlI,,,,,,PHI:9366; PHI:9368,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative autoinducer synthetase,,,pyocyanin production,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31194839,PubMed,10.1371/journal.ppat.1007820,PLoS Pathog. 2019 Jun 13;15(6):e1007820,bbassler@princeton.edu,"The rhlR* ΔrhlI ΔpqsE mutant P. aeruginosa strain killed 75% of the C.elegans, however, less than the wildtype, by contrast, the ΔrhlI ΔpqsE strain was highly attenuated, killing only 2% of the nematodes.",A R McCready 2019,2019,3 genes,McCready-2019-An autoinducer-independent RhlR,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14444,PHI:9368,UniProt,P20581,GenBank,AAA88447,,,PAO1,pqsE,,,,,,PHI:9366; PHI:9367,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,2-aminobenzoylacetyl-CoA thioesterase,,,pyocyanin production,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31194839,PubMed,10.1371/journal.ppat.1007820,PLoS Pathog. 2019 Jun 13;15(6):e1007820,bbassler@princeton.edu,"The rhlR* ΔrhlI ΔpqsE mutant P. aeruginosa strain killed 75% of the C.elegans, however, less than the wildtype, by contrast, the ΔrhlI ΔpqsE strain was highly attenuated, killing only 2% of the nematodes.",A R McCready 2019,2019,3 genes,McCready-2019-An autoinducer-independent RhlR,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14445,PHI:9369,UniProt,Q7CKC8,GenBank,ACN50512,,,Kimberley53,nlpD,,,,,,,632,Yersinia pestis,,Kim53,bubonic plague,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,lipoprotein,,,,reduced virulence,,,,,,,,reduced,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene mutation; gene complementation,,,YVS,31170147,PubMed,10.1371/journal.pntd.0007449,PLoS Negl Trop Dis. 2019 Jun 6;13(6):e0007449,emmym@iibr.gov.il,NlpD essentiality in iron utilization involved the activity of the Tat system.,A Tidhar 2019,2019,4 genes,Tidhar-2019-Disruption of the NlpD lipoprotein,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14446,PHI:9370,UniProt,Q8ZAM2,GenBank,CAL22364,,,CO92,tatA,,,,,,,632,Yersinia pestis,,Kim53,bubonic plague,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene mutation; gene complementation,,,YVS,31170147,PubMed,10.1371/journal.pntd.0007449,PLoS Negl Trop Dis. 2019 Jun 6;13(6):e0007449,emmym@iibr.gov.il,NlpD essentiality in iron utilization involved the activity of the Tat system.,A Tidhar 2019,2019,4 genes,Tidhar-2019-Disruption of the NlpD lipoprotein,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14447,PHI:9371,UniProt,A0A3N4B6D7,GenBank,AAS63441,,,91001,tatC,,,,,,,632,Yersinia pestis,,Kim53,bubonic plague,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene mutation; gene complementation,,,YVS,31170147,PubMed,10.1371/journal.pntd.0007449,PLoS Negl Trop Dis. 2019 Jun 6;13(6):e0007449,emmym@iibr.gov.il,NlpD essentiality in iron utilization involved the activity of the Tat system.,A Tidhar 2019,2019,4 genes,Tidhar-2019-Disruption of the NlpD lipoprotein,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14448,PHI:9372,UniProt,A0A380PMR4,GenBank,ROZ92390,,,FDAARGOS_605,amiC,,,,,,,632,Yersinia pestis,,Kim53,bubonic plague,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,N-acetylmuramoyl-L-alanine amidase,,,,unaffected pathogenicity,,,,,,,,,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene mutation,,,YVS,31170147,PubMed,10.1371/journal.pntd.0007449,PLoS Negl Trop Dis. 2019 Jun 6;13(6):e0007449,emmym@iibr.gov.il,NlpD essentiality in iron utilization involved the activity of the Tat system.,A Tidhar 2019,2019,4 genes,Tidhar-2019-Disruption of the NlpD lipoprotein,BATCH_094B,2019-08-01,MC,,,,,,,,,,,,,
,,Record 14449,PHI:9373,UniProt,A0A0L9JUE7,GenBank,AIY53972,,,C50041,tcpS,,,,,,,28901,Salmonella enterica,,subsp. enterica serovar Enteritidis strain C50041,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31315056,PubMed,10.1016/j.celrep.2019.06.048,Cell Rep. 2019 Jul 16;28(3):804-818.e7,jiao@yzu.edu.cn,"S. Enteritidis effector TcpS inhibited TLR specific signaling, thus suppressing inflammatory responsesby escaping the innate immunity and promoting the bacterial survival in the early stage of infection.",D Xiong 2019,2019,1 gene,Xiong-2019-Salmonella Coiled-Coil- and TIR-Con,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14450,PHI:9373,UniProt,A0A0L9JUE7,GenBank,AIY53972,,,C50041,tcpS,,,,,,,28901,Salmonella enterica,,subsp. enterica serovar Enteritidis strain C50041,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31315056,PubMed,10.1016/j.celrep.2019.06.048,Cell Rep. 2019 Jul 16;28(3):804-818.e7,jiao@yzu.edu.cn,"S. Enteritidis effector TcpS inhibited TLR specific signaling, thus suppressing inflammatory responsesby escaping the innate immunity and promoting the bacterial survival in the early stage of infection.",D Xiong 2019,2019,1 gene,Xiong-2019-Salmonella Coiled-Coil- and TIR-Con,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14451,PHI:9374,UniProt,B3GV24,GenBank,VFC16102,,,Liv050a,slpA,,,,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,cecum; colon,S-layer precursor protein,,,,loss of pathogenicity,,,,,,reduced,,,wild type,no,,,,,,,gene mutation; gene complementation,,,YVS,28878013,PubMed,10.1126/scitranslmed.aah6813,Sci Transl Med. 2017 Sep 6;9(406). pii: eaah6813,ggovons@gmail.com,S-layer null mutants were completely avirulent despite persistent gut colonization.,J A Kirk 2017,2017,1 gene,Kirk-2017-New class of precision antimicrobial,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14452,PHI:9375,,no data found,GenBank,KAA1351064,,,EcFF133,irp2,,,,,,,562,Escherichia coli,,A1749,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder; kidney,yersiniabactin non-ribosomal peptide synthetase,,,yersiniabactin synthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29702209,PubMed,10.1016/j.micpath.2018.04.048,Microb Pathog. 2018 Jul;120:128-131,johns007@umn.edu,Irp2 mutants were attenuated mildly in the UTI model and profoundly in the sepsis model.,J R Johnson 2018,2018,1 gene,Johnson-2018-Contribution of yersiniabactin to,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14453,PHI:9375,,no data found,GenBank,KAA1351064,,,EcFF133,irp2,,,,,,,562,Escherichia coli,,A1749,sepsis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,yersiniabactin non-ribosomal peptide synthetase,,,yersiniabactin synthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29702209,PubMed,10.1016/j.micpath.2018.04.048,Microb Pathog. 2018 Jul;120:128-131,johns007@umn.edu,Irp2 mutants were attenuated mildly in the UTI model and profoundly in the sepsis model.,J R Johnson 2018,2018,1 gene,Johnson-2018-Contribution of yersiniabactin to,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14454,PHI:9376,UniProt,K9GAI0,GenBank,EKV18930,,,Pd1,prtT (PDIP_25240),,,,,,,36651,Penicillium digitatum,1170230,Pd1,green rot,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelate; cv. Lane late,,,fruit,transcriptional activator of proteases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,"ZnSO4; CuSO4; MnSO4; FeSO4; 1,10-phenanthroline; bestatin; phosphoramidon; EDTA; EGTA; ferrozine; DETC; 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride (AEBSF); pepstatin A; E-64","ZnSO4: CHEBI:35176; CuSO4: CHEBI:23414; MnSO4: CHEBI:86360; FeSO4: CHEBI:75832; 1,10-phenanthroline: CHEBI:44975; bestatin: CHEBI:3070; phosphoramidon: CHEBI:45353; EDTA: CHEBI:64758; EGTA: CHEBI:30740; ferrozine CAS no.: CAS:63451-29-6; DETC: CHEBI:144359; 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride (AEBSF) CAS no.: CAS:30827-99-7, 7989; pepstatin ACHEBI  E-64: CHEBI:30270",,,,,gene deletion: full,,,YVS,31336863,PubMed,10.3390/microorganisms7070198,Microorganisms. 2019 Jul 12;7(7). pii: E198,lgonzalez@iata.csic.es,"Deletion of prtT caused a significant loss in secreted protease activity during in vitro growth assays, however, there was no effect on virulence.",A R Ballester 2019,2019,1 gene,Ballester-2019-Functional and Pharmacological,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14455,PHI:9377,UniProt,G2X1Q3,GenBank,EGY22789,,,VdLs.17,VdMsn2 (VDAG_04227),chromosome 1,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,269719,Cotinus coggygria (related: smokebush),,,,seedling,C2H2 transcriptionfactor,,,,reduced virulence,,,yes,yes,,reduced,,reduced; aberrant,wild type,no,calcofluor white (CFW); Congo red,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,29122172,PubMed,10.1016/j.funbio.2017.08.005,Fungal Biol. 2017 Dec;121(12):1001-1010,ylwang@bjfu.edu.cn,VdMsn2 deletion mutants produce significantly more microsclerotia than the wild-type and exhibit attenuated virulence to smoke trees because of poor penetration.,L Tian 2017,2017,1 gene,Tian-2017-The C2H2 transcription factor VdMsn2,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14456,PHI:9378,UniProt,G2XIN6,GenBank,EGY20389,,,VdLs.17,VdOGDH (VDAG_10018),chromosome 4,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Coker 312,,,seedling,alpha-oxoglutarate dehydrogenase,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,hydrogen peroxide,hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31422448,PubMed,10.1007/s00294-019-01025-2,Curr Genet. 2019 Aug 17,guoning@ahau.edu.cn,VdOGDH was important for energy metabolism and melanin accumulation.,X Li 2019,2019,1 gene,Li-2019-VdOGDH is involved in energy metabolis,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14457,PHI:9379,,no data found,GenBank,CDK43174,,,QOC1,InlP1,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"In Caco2 cells, the invasion efficiencies of the inlP1 and the inlP3 deletion mutant strain were significantly lower compared to the wild type.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14458,PHI:9380,,no data found,,,,,,InlPq,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"In Caco2 cells, the invasion efficiencies of the inlP1 and the inlP3 deletion mutant strain were significantly lower compared to the wild type.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14459,PHI:9381,,no data found,GenBank,EHY61402,,,FSL J1-208,InlP3,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"In Caco2 cells, the invasion efficiencies of the inlP1 and the inlP3 deletion mutant strain were significantly lower compared to the wild type.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14460,PHI:9382,,no data found,GenBank,QCC72463,,,QOC1,InlP4,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"In Caco2 cells, the invasion efficiencies of the inlP1 and the inlP3 deletion mutant strain were significantly lower compared to the wild type.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14461,PHI:9379,,no data found,GenBank,CDK43174,,,QOC1,InlP1,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,primates,9606,Homo sapiens (related: human),Hep-G2 cell line,,,Hep-G2 cell,internalin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"The complemented inlP1, inlP3 and inlP4 mutant strain showed significantly enhanced invasion efficiencies in HEPG2 cells.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14462,PHI:9380,,no data found,,,,,,InlPq,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,primates,9606,Homo sapiens (related: human),Hep-G2 cell line,,,Hep-G2 cell,internalin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"The complemented inlP1, inlP3 and inlP4 mutant strain showed significantly enhanced invasion efficiencies in HEPG2 cells.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14463,PHI:9381,,no data found,GenBank,EHY61402,,,FSL J1-208,InlP3,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,primates,9606,Homo sapiens (related: human),Hep-G2 cell line,,,Hep-G2 cell,internalin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"The complemented inlP1, inlP3 and inlP4 mutant strain showed significantly enhanced invasion efficiencies in HEPG2 cells.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14464,PHI:9382,,no data found,GenBank,QCC72463,,,QOC1,InlP4,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,primates,9606,Homo sapiens (related: human),Hep-G2 cell line,,,Hep-G2 cell,internalin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"The complemented inlP1, inlP3 and inlP4 mutant strain showed significantly enhanced invasion efficiencies in HEPG2 cells.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14465,PHI:9379,,no data found,GenBank,CDK43174,,,QOC1,InlP1,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; liver; spleen,internalin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"Colonization of the liver and the spleen was slightly, but significantly reduced 72 h post infection in an oral mouse infection model when inlP1 or inlP4 was deleted.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14466,PHI:9380,,no data found,,,,,,InlPq,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine,internalin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"Colonization of the liver and the spleen was slightly, but significantly reduced 72 h post infection in an oral mouse infection model when inlP1 or inlP4 was deleted.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14467,PHI:9381,,no data found,GenBank,EHY61402,,,FSL J1-208,InlP3,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine,internalin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"Colonization of the liver and the spleen was slightly, but significantly reduced 72 h post infection in an oral mouse infection model when inlP1 or inlP4 was deleted.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14468,PHI:9382,,no data found,GenBank,QCC72463,,,QOC1,InlP4,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine; liver; spleen,internalin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"Colonization of the liver and the spleen was slightly, but significantly reduced 72 h post infection in an oral mouse infection model when inlP1 or inlP4 was deleted.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14469,PHI:9380,,no data found,,,,,,InlPq,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,internalin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"Colonization of the liver and the spleen was slightly, but significantly reduced 72 h post infection in an oral mouse infection model when inlP1 or inlP4 was deleted.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14470,PHI:9381,,no data found,GenBank,EHY61402,,,FSL J1-208,InlP3,,,,,,,1639,Listeria monocytogenes,1288293,QOC1,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,internalin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31396177,PubMed,10.3389/fmicb.2019.01644,Front Microbiol. 2019 Jul 23;10:1644,kathrin.rychli@vetmeduni.ac.at,"Colonization of the liver and the spleen was slightly, but significantly reduced 72 h post infection in an oral mouse infection model when inlP1 or inlP4 was deleted.",E Harter 2019,2019,4 genes,Harter-2019-The Novel Internalins InlP1 and In,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14471,PHI:9383,UniProt,Q54972,GenBank,AAA27018,,,,PspA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),,,,neutrophil,pneumococcal surface protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31398527,PubMed,10.1016/j.micpath.2019.103653,Microb Pathog. 2019 Aug 6;136:103653,shaper.mirza@lums.edu.pk,PspA mutants were more susceptible to bactericidal effects of NETs.,P J Martinez 2019,2019,1 gene,Martinez-2019-PspA facilitates evasion of pneu,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14472,PHI:9383,UniProt,Q54972,GenBank,AAA27018,,,,PspA,,,,,,,1313,Streptococcus pneumoniae,880525,WU2,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),,,,neutrophil,pneumococcal surface protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31398527,PubMed,10.1016/j.micpath.2019.103653,Microb Pathog. 2019 Aug 6;136:103653,shaper.mirza@lums.edu.pk,PspA mutants were more susceptible to bactericidal effects of NETs.,P J Martinez 2019,2019,1 gene,Martinez-2019-PspA facilitates evasion of pneu,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14473,PHI:9383,UniProt,Q54972,GenBank,AAA27018,,,,PspA,,,,,,,1313,Streptococcus pneumoniae,,EF3030,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),,,,neutrophil,pneumococcal surface protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31398527,PubMed,10.1016/j.micpath.2019.103653,Microb Pathog. 2019 Aug 6;136:103653,shaper.mirza@lums.edu.pk,PspA mutants were more susceptible to bactericidal effects of NETs.,P J Martinez 2019,2019,1 gene,Martinez-2019-PspA facilitates evasion of pneu,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14474,PHI:9384,UniProt,A0A0H2YXK5,GenBank,ABJ00255,,,APEC O1,ybjX,,,,,,PHI:9385,562,Escherichia coli,,AE17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryonic fibroblast cell line,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31326704,PubMed,10.1016/j.rvsc.2019.07.008,Res Vet Sci. 2019 Aug;125:279-284,qkz@ahau.edu.cn,"The APECΔybjX/pagP mutant strain exhibited reduced invasion of chicken embryo fibroblast (DF-1) cells, but had no effect on virulence in a chicken model.",K Qi 2019,2019,2 genes,Song-2019-Outer membrane proteins YbjX and Pag,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14475,PHI:9385,UniProt,A0A0H2YXJ2,GenBank,ABJ00040,,,APEC O1,pagP,,,,,,PHI:9384,562,Escherichia coli,,AE17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryonic fibroblast cell line,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31326704,PubMed,10.1016/j.rvsc.2019.07.008,Res Vet Sci. 2019 Aug;125:279-284,qkz@ahau.edu.cn,"The APECΔybjX/pagP mutant strain exhibited reduced invasion of chicken embryo fibroblast (DF-1) cells, but had no effect on virulence in a chicken model.",K Qi 2019,2019,2 genes,Song-2019-Outer membrane proteins YbjX and Pag,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14476,PHI:9384,UniProt,A0A0H2YXK5,GenBank,ABJ00255,,,APEC O1,ybjX,,,,,,PHI:9385,562,Escherichia coli,,AE17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31326704,PubMed,10.1016/j.rvsc.2019.07.008,Res Vet Sci. 2019 Aug;125:279-284,qkz@ahau.edu.cn,"The APECΔybjX/pagP mutant strain exhibited reduced invasion of chicken embryo fibroblast (DF-1) cells, but had no effect on virulence in a chicken model.",K Qi 2019,2019,2 genes,Song-2019-Outer membrane proteins YbjX and Pag,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14477,PHI:9385,UniProt,A0A0H2YXJ2,GenBank,ABJ00040,,,APEC O1,pagP,,,,,,PHI:9384,562,Escherichia coli,,AE17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31326704,PubMed,10.1016/j.rvsc.2019.07.008,Res Vet Sci. 2019 Aug;125:279-284,qkz@ahau.edu.cn,"The APECΔybjX/pagP mutant strain exhibited reduced invasion of chicken embryo fibroblast (DF-1) cells, but had no effect on virulence in a chicken model.",K Qi 2019,2019,2 genes,Song-2019-Outer membrane proteins YbjX and Pag,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14478,PHI:9386,UniProt,K3W2C6,GenBank,EKJ77415,,,CS3096,FpNPS9 (FPSE_02493),,,,,,,101028,Fusarium pseudograminearum,,WZ-8A,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Aikang 58,,,coleoptile; spikelet,non-ribosomal peptide synthetase,,,,reduced virulence,,,,yes,,wild type,,wild type,,no,NaCl; KCl; sorbitol; SDS; Congo red; H2O2,NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; sodium dodecyl sulfate: CHEBI:8984; Congo red: CHEBI:34653; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31312935,PubMed,10.1007/s00294-019-01017-2,Curr Genet. 2019 Jul 16,shengliding@henau.edu.cn,Deoxynivalenol production in the mutant was signifcantly reduced.,R Kang 2019,2019,1 gene,Kang-2019-Expression of Fusarium pseudogramine,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14479,PHI:9386,UniProt,K3W2C6,GenBank,EKJ77415,,,CS3096,FpNPS9 (FPSE_02493),,,,,,,101028,Fusarium pseudograminearum,,WZ-8A,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Guomai 301,,,coleoptile; spikelet,non-ribosomal peptide synthetase,,,,reduced virulence,,,,yes,,wild type,,wild type,,no,NaCl; KCl; sorbitol; SDS; Congo red; H2O2,NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; sodium dodecyl sulfate: CHEBI:8984; Congo red: CHEBI:34653; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31312935,PubMed,10.1007/s00294-019-01017-2,Curr Genet. 2019 Jul 16,shengliding@henau.edu.cn,Deoxynivalenol production in the mutant was signifcantly reduced.,R Kang 2019,2019,1 gene,Kang-2019-Expression of Fusarium pseudogramine,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14480,PHI:9386,UniProt,K3W2C6,GenBank,EKJ77415,,,CS3096,FpNPS9 (FPSE_02493),,,,,,,101028,Fusarium pseudograminearum,,WZ-8A,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhoumai 24,,,coleoptile; spikelet,non-ribosomal peptide synthetase,,,,reduced virulence,,,,yes,,wild type,,wild type,,no,NaCl; KCl; sorbitol; SDS; Congo red; H2O2,NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; sodium dodecyl sulfate: CHEBI:8984; Congo red: CHEBI:34653; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31312935,PubMed,10.1007/s00294-019-01017-2,Curr Genet. 2019 Jul 16,shengliding@henau.edu.cn,Deoxynivalenol production in the mutant was signifcantly reduced.,R Kang 2019,2019,1 gene,Kang-2019-Expression of Fusarium pseudogramine,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14481,PHI:9387,UniProt,Q9HXD2,GenBank,AAG07267,,,PAO1,AnvM (PA3880),,,,mvfR,UniProt: Q9I4X0; GenBank: AE004533_3,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,alveolar macrophage; lung,anaerobic and virulence modulator,,,,reduced virulence,,,,,,,,,,no,H2O2; cumene hydroperoxide,H2O2: CHEBI:16240; cumene hydroperoxide: CHEBI:78673,,,,,gene deletion: full; gene complementation,,,YVS,31337721,PubMed,10.1128/mBio.01362-19,MBio. 2019 Jul 23;10(4). pii: e01362-19,xindeng@cityu.edu.hk,"Loss of the PA3880 protein significantly blunted the pathogenicity of P. aeruginosa, resulting in increased host survival, decreased bacterial burdens, reduced inflammatory responses, and fewer lung injuries in challenged mice hosts.",Y Zhang 2019,2019,1 gene,Zhang-2019-Pseudomonas aeruginosa Regulatory P,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14482,PHI:9387,UniProt,Q9HXD2,GenBank,AAG07267,,,PAO1,AnvM (PA3880),,AnvM C44S,,mvfR,UniProt: Q9I4X0; GenBank: AE004533_3,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),MH-S cell line,,,alveolar macrophage cell line,anaerobic and virulence modulator,,,,reduced virulence,,,,,,,,,,no,H2O2; cumene hydroperoxide,H2O2: CHEBI:16240; cumene hydroperoxide: CHEBI:78673,,,,,gene mutation,,,YVS,31337721,PubMed,10.1128/mBio.01362-19,MBio. 2019 Jul 23;10(4). pii: e01362-19,xindeng@cityu.edu.hk,"The complementation strain with AnvM C44S (Cys44 was mutated to Ser) had significantly reduced levels of phagocytosis and ROS production in AM, suggesting that the Cys44 was a critical site for the full function of AnvM.",Y Zhang 2019,2019,1 gene,Zhang-2019-Pseudomonas aeruginosa Regulatory P,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14483,PHI:9388,UniProt,J7QX79,GenBank,AJE54458,,,789,Pfs,,,,,,,562,Escherichia coli,,DE17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryonic fibroblast cell line,5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase,,,LuxS/Pfs pathway,reduced virulence,,,,,,,,wild type,,no,D-mannose,D-mannose: CHEBI:16024,,,,,gene deletion: full; gene complementation,,,YVS,29102113,PubMed,10.1016/j.vetmic.2017.10.017,Vet Microbiol. 2017 Nov;211:160-168,hanxgan@163.com,The DE17Δpfs strain exhibited significantly reduced adherence and invasion.,D Xu 2017,2017,2 genes,Xu-2017-Different activated methyl cycle pathw,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14484,PHI:9388,UniProt,J7QX79,GenBank,AJE54458,,,789,Pfs,,,,,,PHI:9389,562,Escherichia coli,,DE17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryonic fibroblast cell line,5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase,,,LuxS/Pfs pathway,unaffected pathogenicity,,,,,,,,wild type,,no,D-mannose,D-mannose: CHEBI:16024,,,,,gene deletion: full; gene complementation,,,YVS,29102113,PubMed,10.1016/j.vetmic.2017.10.017,Vet Microbiol. 2017 Nov;211:160-168,hanxgan@163.com,The DE17Δpfs strain exhibited significantly reduced adherence and invasion.,D Xu 2017,2017,2 genes,Xu-2017-Different activated methyl cycle pathw,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14485,PHI:9389,UniProt,K7QUT8,GenBank,AFV74796,,,V14447,sahH,,,,,,PHI:9388,562,Escherichia coli,,DE17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryonic fibroblast cell line,S-adenosyl-L-homocysteine hydrolase,,,SahH pathway,unaffected pathogenicity,,,,,,,,wild type,,no,D-mannose,D-mannose: CHEBI:16024,,,,,heterologous expression,,,YVS,29102113,PubMed,10.1016/j.vetmic.2017.10.017,Vet Microbiol. 2017 Nov;211:160-168,hanxgan@163.com,The DE17Δpfs strain exhibited significantly reduced adherence and invasion.,D Xu 2017,2017,2 genes,Xu-2017-Different activated methyl cycle pathw,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14486,PHI:9389,UniProt,K7QUT8,GenBank,AFV74796,,,V14447,sahH,,,,,,,562,Escherichia coli,,DE17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryonic fibroblast cell line,S-adenosyl-L-homocysteine hydrolase,,,SahH pathway,reduced virulence,,,,,,,,wild type,,no,D-mannose,D-mannose: CHEBI:16024,,,,,heterologous expression,,,YVS,29102113,PubMed,10.1016/j.vetmic.2017.10.017,Vet Microbiol. 2017 Nov;211:160-168,hanxgan@163.com,The DE17Δpfs strain exhibited significantly reduced adherence and invasion.,D Xu 2017,2017,2 genes,Xu-2017-Different activated methyl cycle pathw,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14487,PHI:9388,UniProt,J7QX79,GenBank,AJE54458,,,789,Pfs,,,,,,,562,Escherichia coli,,DE17,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,liver; spleen; kidney; blood,5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase,,,LuxS/Pfs pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29102113,PubMed,10.1016/j.vetmic.2017.10.017,Vet Microbiol. 2017 Nov;211:160-168,hanxgan@163.com,The DE17Δpfs and SahH-DE17Δpfs strains showed reduced survival in vivo.,D Xu 2017,2017,2 genes,Xu-2017-Different activated methyl cycle pathw,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14488,PHI:9388,UniProt,J7QX79,GenBank,AJE54458,,,789,Pfs,,,,,,PHI:9389,562,Escherichia coli,,DE17,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,liver; spleen; kidney; blood,5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase,,,LuxS/Pfs pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29102113,PubMed,10.1016/j.vetmic.2017.10.017,Vet Microbiol. 2017 Nov;211:160-168,hanxgan@163.com,The DE17Δpfs and SahH-DE17Δpfs strains showed reduced survival in vivo.,D Xu 2017,2017,2 genes,Xu-2017-Different activated methyl cycle pathw,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14489,PHI:9389,UniProt,K7QUT8,GenBank,AFV74796,,,V14447,sahH,,,,,,PHI:9388,562,Escherichia coli,,DE17,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,liver; spleen; kidney; blood,S-adenosyl-L-homocysteine hydrolase,,,SahH pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,heterologous expression,,,YVS,29102113,PubMed,10.1016/j.vetmic.2017.10.017,Vet Microbiol. 2017 Nov;211:160-168,hanxgan@163.com,The DE17Δpfs and SahH-DE17Δpfs strains showed reduced survival in vivo.,D Xu 2017,2017,2 genes,Xu-2017-Different activated methyl cycle pathw,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14490,PHI:9389,UniProt,K7QUT8,GenBank,AFV74796,,,V14447,sahH,,,,,,,562,Escherichia coli,,DE17,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,liver; spleen; kidney; blood,S-adenosyl-L-homocysteine hydrolase,,,SahH pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,heterologous expression,,,YVS,29102113,PubMed,10.1016/j.vetmic.2017.10.017,Vet Microbiol. 2017 Nov;211:160-168,hanxgan@163.com,The DE17Δpfs and SahH-DE17Δpfs strains showed reduced survival in vivo.,D Xu 2017,2017,2 genes,Xu-2017-Different activated methyl cycle pathw,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14491,PHI:9390,UniProt,A0A2J8FBI5,GenBank,PNH46024,,,12251,VdSsk2 (VD0003_g9086),,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,seedling,mitogen activated protein kinase kinase kinase,,,melanin biosynthesis,reduced virulence,,no,yes,no,,,,wild type,,no,NaCl; sorbitol; fludioxonil; iprodione; calcofluor white; Congo red; CaCl2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,31292234,PubMed,10.1128/mSphere.00426-19,mSphere. 2019 Jul 10;4(4). pii: e00426-19,ylwang@bjfu.edu.cn,"Deletion of VdSsk2, but not VdSte11, affected responses to osmotic stress, fungicidal response, and cell wall stressors.",J Yu 2019,2019,2 genes,"Yu-2019-Two Verticillium dahliae MAPKKKs, VdSs",BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14492,PHI:9391,UniProt,A0A366PED9,GenBank,RBQ90958,,,Gwydir1A3,VdSte11,,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,seedling,mitogen activated protein kinase kinase kinase,,,melanin biosynthesis,loss of pathogenicity,,yes,yes,yes,,,,reduced; aberrant,,no,NaCl; sorbitol; fludioxonil; iprodione; calcofluor white; Congo red; CaCl2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,31292234,PubMed,10.1128/mSphere.00426-19,mSphere. 2019 Jul 10;4(4). pii: e00426-19,ylwang@bjfu.edu.cn,"Deletion of VdSsk2, but not VdSte11, affected responses to osmotic stress, fungicidal response, and cell wall stressors.",J Yu 2019,2019,2 genes,"Yu-2019-Two Verticillium dahliae MAPKKKs, VdSs",BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14493,PHI:9392,UniProt,Q4WV27,GenBank,EAL91549,,,Af293,cofilin (AFUA_5G10570),chromosome 5,D19A-R21A; K36A,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,actin-depolymerizing factor family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,simvastatin; terbinafine,simvastatin: CHEBI:9150; terbinafine: CHEBI:9448,,,,,gene mutation: characterised,,,YVS,29483117,PubMed,10.1128/AAC.01659-17,Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e01659-17,hanlicdc@163.com,"Mutation of charged residues (D11A-E12A, K26A, D54A, and E56A) in cofilin essential for mitochondrial function led to apoptosis in A. fumigatus.",Z Lu 2018,2018,1 gene,Lu-2018-Identification and Characterization of,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14494,PHI:9392,UniProt,Q4WV27,GenBank,EAL91549,,,Af293,cofilin (AFUA_5G10570),chromosome 5,E48A,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80),aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,actin-depolymerizing factor family protein,,,,unaffected pathogenicity,,,,,,,,,,no,simvastatin; terbinafine,simvastatin: CHEBI:9150; terbinafine: CHEBI:9448,,,,,gene mutation: characterised,,,YVS,29483117,PubMed,10.1128/AAC.01659-17,Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e01659-17,hanlicdc@163.com,"Mutation of charged residues (D11A-E12A, K26A, D54A, and E56A) in cofilin essential for mitochondrial function led to apoptosis in A. fumigatus.",Z Lu 2018,2018,1 gene,Lu-2018-Identification and Characterization of,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14495,PHI:9393,UniProt,W7M195,GenBank,EWG45353,,,7600,FvSec4 (FVEG_06175),chromosome 2,,,,,,117187,Fusarium verticillioides,334819,7600,stalk rot (corn),monocots,4577,Zea mays (related: maize),cv. Silver Queen,,,seedling,Rab GTPase,,,fumonisin B1 production,reduced virulence,no,,,,,reduced,wild type,reduced,wild type,no,SDS; Congo red; H2O2,sodium dodecyl sulfate: CHEBI:8984; Congo red: CHEBI:34653; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31292685,PubMed,10.1007/s00294-019-01013-6,Curr Genet. 2019 Jul 11,wbshim@tamu.edu,The mutant exhibited defect in corn stalk rot virulence and also signifcant alteration of fumonisin B1 production.,H Yan 2019,2019,1 gene,Yan-2019-A Rab GTPase protein FvSec4 is necess,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14496,PHI:9394,UniProt,A0A112UV06,GenBank,CWW35875,,,2842STDY5753961,NOX,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,infection,primates,9606,Homo sapiens (related: human),U-251MG cell line,,,glioma cell line,NADH oxidase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28916475,PubMed,10.1016/j.freeradbiomed.2017.09.003,Free Radic Biol Med. 2017 Nov;112:608-615,lisen_1027@126.com,Nox mutant strain (Δnox) had enhanced invasiveness during the invasion of glial cells and mice brain compared to wildtype strain.,S Li 2017,2017,1 gene,Li-2017-Deletion of NADH oxidase in Listeria m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14497,PHI:9394,UniProt,A0A112UV06,GenBank,CWW35875,,,2842STDY5753961,NOX,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,NADH oxidase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28916475,PubMed,10.1016/j.freeradbiomed.2017.09.003,Free Radic Biol Med. 2017 Nov;112:608-615,lisen_1027@126.com,Nox mutant strain (Δnox) had enhanced invasiveness during the invasion of glial cells and mice brain compared to wildtype strain.,S Li 2017,2017,1 gene,Li-2017-Deletion of NADH oxidase in Listeria m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14498,PHI:9395,UniProt,M2YPW9,GenBank,XP_007930394,,,,PKS8-4,,,,,,,1873960,Pseudocercospora fijiensis,,10CR1-24,black sigatoka,monocots,4641,Musa acuminata (related: dwarf banana),,,,leaf,polyketide synthase,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: cluster,,,YVS,31344104,PubMed,10.1371/journal.pone.0220319,PLoS One. 2019 Jul 25;14(7):e0220319,margaret_daub@ncsu.edu,"A disruption mutant of pks8-4 retained normal pathogenicity on banana, and no differences were observed in growth, conidial production, and spermagonia production.",R D Noar 2019,2019,1 gene,Noar-2019-A polyketide synthase gene cluster a,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14499,PHI:9396,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15II (TGME49_275470),chromosome X,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,primates,9606,Homo sapiens (related: human),T-REx-293 cell line,,,embryonic kidney cell line,effector protein,,,NF-kappaB pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31311877,PubMed,10.1128/mBio.00808-19,MBio. 2019 Jul 16;10(4). pii: e00808-19,jsaeij@ucdavis.edu,"Deletion of TRAF-binding sites in GRA15 greatly reduces its ability to activate the NF-kappaB pathway, and TRAF2 knockout cells have impaired GRA15-mediated NF-kappaB activation.",LO Sangaré 2019,2019,1 gene,Sangare-2019-Toxoplasma GRA15 Activates the NF,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14500,PHI:9397,UniProt,A0A0H2ZNJ1,GenBank,ABJ54397,,,D39,AliB (SPD_1357),,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,brain,oligopeptide ABC transporter,,,,reduced virulence,,,,,,,,wild type,,no,hydrogen peroxide; sodium hypochloride; paraquat,hydrogen peroxide: CHEBI:16240; sodium hypochloride: CHEBI:63005; paraquat: CHEBI:34908,,,,,gene mutation,,,YVS,31356624,PubMed,10.1371/journal.ppat.1007987,PLoS Pathog. 2019 Jul 29;15(7):e1007987,sven.hammerschmidt@uni-greifswald.de,"In the mouse meningitis model, AliB-, ComDE-, or AliB-ComDE-deficiency resulted in attenuated meningeal inflammation and disease severity when compared to wild-type.",F Schmidt 2019,2019,3 genes,Schmidt-2019-In vivo proteomics identifies the,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14501,PHI:9398,UniProt,A0A0H2ZM50,GenBank,ABJ53801,,,D39,ComD (SPD_2064),,,,,,PHI:9399,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,brain,putative sensor histidine kinase ComD,,,,reduced virulence,,,,,,,,wild type,,no,hydrogen peroxide; sodium hypochloride; paraquat,hydrogen peroxide: CHEBI:16240; sodium hypochloride: CHEBI:63005; paraquat: CHEBI:34908,,,,,gene mutation,,,YVS,31356624,PubMed,10.1371/journal.ppat.1007987,PLoS Pathog. 2019 Jul 29;15(7):e1007987,sven.hammerschmidt@uni-greifswald.de,"In the mouse meningitis model, AliB-, ComDE-, or AliB-ComDE-deficiency resulted in attenuated meningeal inflammation and disease severity when compared to wild-type.",F Schmidt 2019,2019,3 genes,Schmidt-2019-In vivo proteomics identifies the,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14502,PHI:9399,UniProt,A0A0H2ZLR3,GenBank,ABJ53793,,,D39,ComE (SPD_2063),,,,,,PHI:9398,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,brain,response regulator,,,,reduced virulence,,,,,,,,wild type,,no,hydrogen peroxide; sodium hypochloride; paraquat,hydrogen peroxide: CHEBI:16240; sodium hypochloride: CHEBI:63005; paraquat: CHEBI:34908,,,,,gene mutation,,,YVS,31356624,PubMed,10.1371/journal.ppat.1007987,PLoS Pathog. 2019 Jul 29;15(7):e1007987,sven.hammerschmidt@uni-greifswald.de,"In the mouse meningitis model, AliB-, ComDE-, or AliB-ComDE-deficiency resulted in attenuated meningeal inflammation and disease severity when compared to wild-type.",F Schmidt 2019,2019,3 genes,Schmidt-2019-In vivo proteomics identifies the,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14503,PHI:9397,UniProt,A0A0H2ZNJ1,GenBank,ABJ54397,,,D39,AliB (SPD_1357),,,,,,PHI:9398; PHI:9399,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,brain,oligopeptide ABC transporter,,,,reduced virulence,,,,,,,,wild type,,no,hydrogen peroxide; sodium hypochloride; paraquat,hydrogen peroxide: CHEBI:16240; sodium hypochloride: CHEBI:63005; paraquat: CHEBI:34908,,,,,gene mutation,,,YVS,31356624,PubMed,10.1371/journal.ppat.1007987,PLoS Pathog. 2019 Jul 29;15(7):e1007987,sven.hammerschmidt@uni-greifswald.de,"In the mouse meningitis model, AliB-, ComDE-, or AliB-ComDE-deficiency resulted in attenuated meningeal inflammation and disease severity when compared to wild-type.",F Schmidt 2019,2019,3 genes,Schmidt-2019-In vivo proteomics identifies the,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14504,PHI:9398,UniProt,A0A0H2ZM50,GenBank,ABJ53801,,,D39,ComD (SPD_2064),,,,,,PHI:9397; PHI:9399,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,brain,putative sensor histidine kinase ComD,,,,reduced virulence,,,,,,,,wild type,,no,hydrogen peroxide; sodium hypochloride; paraquat,hydrogen peroxide: CHEBI:16240; sodium hypochloride: CHEBI:63005; paraquat: CHEBI:34908,,,,,gene mutation,,,YVS,31356624,PubMed,10.1371/journal.ppat.1007987,PLoS Pathog. 2019 Jul 29;15(7):e1007987,sven.hammerschmidt@uni-greifswald.de,"In the mouse meningitis model, AliB-, ComDE-, or AliB-ComDE-deficiency resulted in attenuated meningeal inflammation and disease severity when compared to wild-type.",F Schmidt 2019,2019,3 genes,Schmidt-2019-In vivo proteomics identifies the,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14505,PHI:9399,UniProt,A0A0H2ZLR3,GenBank,ABJ53793,,,D39,ComE (SPD_2063),,,,,,PHI:9397; PHI:9398,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,brain,response regulator,,,,reduced virulence,,,,,,,,wild type,,no,hydrogen peroxide; sodium hypochloride; paraquat,hydrogen peroxide: CHEBI:16240; sodium hypochloride: CHEBI:63005; paraquat: CHEBI:34908,,,,,gene mutation,,,YVS,31356624,PubMed,10.1371/journal.ppat.1007987,PLoS Pathog. 2019 Jul 29;15(7):e1007987,sven.hammerschmidt@uni-greifswald.de,"In the mouse meningitis model, AliB-, ComDE-, or AliB-ComDE-deficiency resulted in attenuated meningeal inflammation and disease severity when compared to wild-type.",F Schmidt 2019,2019,3 genes,Schmidt-2019-In vivo proteomics identifies the,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14506,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14507,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14508,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14509,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14510,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14511,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14512,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14513,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14514,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14515,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14516,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14517,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,moths,7137,Galleria mellonella (related: greater wax moth),TruLarv,,,larva,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14518,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14519,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14520,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14521,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14522,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14523,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14524,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14525,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14526,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14527,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14528,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14529,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14530,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14531,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14532,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14533,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14534,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14535,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14536,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14537,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14538,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14539,PHI:9400,UniProt,G8B6X1,GenBank,CCE40203,,,CDC317,RI_SAPP1 (CPAR2_102410),,,,,,PHI:9401; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14540,PHI:9401,UniProt,G8B6Y8,GenBank,CCE40220,,,CDC317,RI_SAPP2 (CPAR2_102580),,,,,,PHI:9400; PHI:9402,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14541,PHI:9402,UniProt,G8B6X2,GenBank,CCE40204,,,CDC317,RI_SAPP3 (CPAR2_102420),,,,,,PHI:9400; PHI:9401,5480,Candida parapsilosis,1431531,GA1,mycosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,peptidase A1 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,glycerol; sorbitol; NaCl; H2O2; CdSO4; menadione; caffeine; calcoflour white; congo red; SDS; CuSO4; CuCl2; EDTA; BPS,glycerol: CHEBI:17754; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CdSO4: CHEBI:50292; menadione: CHEBI:28869; caffeine: CHEBI:27732; calcoflour white: CHEBI:50011; congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414; CuCl2: CHEBI:49553; EDTA: CHEBI:42191; BPS: CHEBI:34372,,,,,gene deletion: full,,,YVS,31434748,PubMed,10.1128/mSphere.00484-19,mSphere. 2019 Aug 21;4(4). pii: e00484-19,gacsera@bio.u-szeged.hu,"SAPP1 and SAPP2 (not SAPP3), influenced host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing and cytokine secretion.",D K Singh 2019,2019,3 genes,Singh-2019-Functional Characterization of Secr,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14542,PHI:9403,UniProt,J9VT55,GenBank,AFR97418,,,H99,cys3 (CNAG_04798),chromosome 10,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,bZip regulatory protein,,,sulfur amino acid biosynthetic pathway,reduced virulence,,,,,,,,reduced,,no,NaCl; KCl; H2O2; SDS; triton; congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; triton: CHEBI:29234; congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31417135,PubMed,10.1038/s41598-019-48433-5,Sci Rep. 2019 Aug 15;9(1):11923,renata.pascon@gmail.com,"Cys3 controls all branches of the sulfur amino acid biosynthesis, and sulfur starvation leads to induction of several amino acid biosynthetic routes.",A T de Melo 2019,2019,1 gene,de Melo-2019-The regulation of the sulfur amin,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14543,PHI:9404,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,primates,9606,Homo sapiens (related: human),HDMEC-IM cell line,,,dermal microvascular endothelial cell,cytolytic peptide toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31401652,PubMed,10.1093/infdis/jiz322,J Infect Dis. 2019 Sep 26;220(9):1477-1488,julian.naglik@kcl.ac.uk,Candidalysin induces immune activation and neutrophil recruitment in vivo.,M Swidergall 2019,2019,1 gene,Swidergall-2019-Candidalysin Is Required for N,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14544,PHI:9404,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,primates,9606,Homo sapiens (related: human),HMEC-1 cell line,,,microvascular endothelial cell line,cytolytic peptide toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31401652,PubMed,10.1093/infdis/jiz322,J Infect Dis. 2019 Sep 26;220(9):1477-1488,julian.naglik@kcl.ac.uk,Candidalysin induces immune activation and neutrophil recruitment in vivo.,M Swidergall 2019,2019,1 gene,Swidergall-2019-Candidalysin Is Required for N,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14545,PHI:9404,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,cytolytic peptide toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31401652,PubMed,10.1093/infdis/jiz322,J Infect Dis. 2019 Sep 26;220(9):1477-1488,julian.naglik@kcl.ac.uk,Candidalysin induces immune activation and neutrophil recruitment in vivo.,M Swidergall 2019,2019,1 gene,Swidergall-2019-Candidalysin Is Required for N,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14546,PHI:9404,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; brain; kidney,cytolytic peptide toxin,,,,reduced virulence,,,,,,,,,,no,5-fluorouracil,5-fluorouracil: CHEBI:46345,,,,,gene deletion: full; gene complementation,,,YVS,31401652,PubMed,10.1093/infdis/jiz322,J Infect Dis. 2019 Sep 26;220(9):1477-1488,julian.naglik@kcl.ac.uk,Candidalysin induces immune activation and neutrophil recruitment in vivo.,M Swidergall 2019,2019,1 gene,Swidergall-2019-Candidalysin Is Required for N,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14547,PHI:9405,UniProt,I1RCP1,GenBank,CEF73487,,,PH-1,CCH1 (FGSG_01364),chromosome 1,,,,,,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,EF-hand domain-containing protein,,,,reduced virulence,,,,,,reduced,aberrant,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14548,PHI:9406,UniProt,I1RTB7,GenBank,CEF84370,,,PH-1,MID1 (FGSG_07418),chromosome 4,,,,,,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,uncharacterized protein,,,,reduced virulence,,,,,,reduced,aberrant,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14549,PHI:9407,UniProt,I3VPY1,GenBank,AFK83825,,,PH-1,FIG1 (FGSG_06302),,,,,,,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,factor-induced protein 1,,,,reduced virulence,,,,,,wild type,reduced,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14550,PHI:9405,UniProt,I1RCP1,GenBank,CEF73487,,,PH-1,CCH1 (FGSG_01364),chromosome 1,,,,,PHI:9406,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,EF-hand domain-containing protein,,,,reduced virulence,,,,,,reduced,aberrant,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14551,PHI:9406,UniProt,I1RTB7,GenBank,CEF84370,,,PH-1,MID1 (FGSG_07418),chromosome 4,,,,,PHI:9405,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,uncharacterized protein,,,,reduced virulence,,,,,,reduced,aberrant,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14552,PHI:9405,UniProt,I1RCP1,GenBank,CEF73487,,,PH-1,CCH1 (FGSG_01364),chromosome 1,,,,,PHI:9407,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,EF-hand domain-containing protein,,,,reduced virulence,,,,,,wild type,reduced,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14553,PHI:9407,UniProt,I3VPY1,GenBank,AFK83825,,,PH-1,FIG1 (FGSG_06302),,,,,,PHI:9405,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,factor-induced protein 1,,,,reduced virulence,,,,,,wild type,reduced,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14554,PHI:9406,UniProt,I1RTB7,GenBank,CEF84370,,,PH-1,MID1 (FGSG_07418),chromosome 4,,,,,PHI:9407,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,uncharacterized protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14555,PHI:9407,UniProt,I3VPY1,GenBank,AFK83825,,,PH-1,FIG1 (FGSG_06302),,,,,,PHI:9406,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,factor-induced protein 1,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14556,PHI:9405,UniProt,I1RCP1,GenBank,CEF73487,,,PH-1,CCH1 (FGSG_01364),chromosome 1,,,,,PHI:9406; PHI:9407,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,EF-hand domain-containing protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14557,PHI:9406,UniProt,I1RTB7,GenBank,CEF84370,,,PH-1,MID1 (FGSG_07418),chromosome 4,,,,,PHI:9405; PHI:9407,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,uncharacterized protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14558,PHI:9407,UniProt,I3VPY1,GenBank,AFK83825,,,PH-1,FIG1 (FGSG_06302),,,,,,PHI:9405; PHI:9406,5518,Fusarium graminearum,,FSK511,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,factor-induced protein 1,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,CaCl2; EGTA,CaCl2: CHEBI:3312; EGTA: CHEBI:30740,,,,,gene deletion: full,,,YVS,29175365,PubMed,10.1016/j.fgb.2017.11.005,Fungal Genet Biol. 2018 Feb;111:30-46,sxk55@psu.edu,"Disruption of CCH1, MID1 and FIG1 negatively affects the periodicity and interval of [Ca2+]c pulses, and the effect of mutation is influenced by external Ca2+ concentration.",H S Kim 2017,2017,3 gene,Kim-2017-Roles of three Fusarium graminearum m,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14559,PHI:9408,UniProt,G2WVA9,GenBank,EGY20234,,,VdLs.17,VdSkn7 (VDAG_02250),chromosome 7,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,root,two-component response regulator,,,,reduced virulence,,,yes,,,reduced,,wild type,wild type,no,KCl; NaCl; sorbitol; calcofluor white; sodium dodecyl sulfate; congo red; hydrogen peroxide; t-butyl hydrogen peroxide,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; congo red: CHEBI:34653; hydrogen peroxide: CHEBI:16240; t-butyl hydrogen peroxide: CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,28917999,PubMed,10.1016/j.fgb.2017.09.002,Fungal Genet Biol. 2017 Nov;108:26-35,ylwang@bjfu.edu.cn,Melanized microsclerotia formation and conidiation were significantly inhibited in the VdSkn7 deletion mutants.,C Tang 2017,2017,1 gene,Tang-2017-The two-component response regulator,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14560,PHI:9409,UniProt,J5K1T7,GenBank,EJP68141,,,ARSEF 2860,Krs (BBA_03037),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,lysine-tRNA synthetase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29029702,PubMed,10.1016/j.funbio.2017.08.003,Fungal Biol. 2017 Nov;121(11):956-965,mgfeng@zju.edu.cn,"Deletion of krs resulted in 10-h delayed germination, decreased (15 %) thermotolerance, and lowered (46 %) UV-B resistance of aerial conidia despite limited impact on conidiation capacity.",X G Zhu 2017,2017,1 gene,Zhu-2017-Lysyl-tRNA synthetase (Krs) acts a vi,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14561,PHI:9410,,no data found,GenBank,BAX74398,,,No.10,psmalpha,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,keratinocyte,phenol-soluble modulin alpha 4 peptide,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29120744,PubMed,10.1016/j.chom.2017.10.008,Cell Host Microbe. 2017 Nov 8;22(5):667-677.e5,yumi01@chiba-u.jp,"The ability of the psmα mutant strain to induce skin disease, epidermal thickening and neutrophil infiltration were impaired compared with the WT and psmβ mutant strains.",S Nakagawa 2017,2017,2 genes,Nakagawa-2017-Staphylococcus aureus Virulent P,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14562,PHI:9411,UniProt,I3G603,GenBank,EIK18987,,,VRS8,psmbeta,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,keratinocyte,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29120744,PubMed,10.1016/j.chom.2017.10.008,Cell Host Microbe. 2017 Nov 8;22(5):667-677.e5,yumi01@chiba-u.jp,"The ability of the psmα mutant strain to induce skin disease, epidermal thickening and neutrophil infiltration were impaired compared with the WT and psmβ mutant strains.",S Nakagawa 2017,2017,2 genes,Nakagawa-2017-Staphylococcus aureus Virulent P,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14563,PHI:9410,,no data found,GenBank,BAX74398,,,No.10,psmalpha,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection,primates,9606,Homo sapiens (related: human),,,,keratinocyte,phenol-soluble modulin alpha 4 peptide,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29120744,PubMed,10.1016/j.chom.2017.10.008,Cell Host Microbe. 2017 Nov 8;22(5):667-677.e5,yumi01@chiba-u.jp,"The ability of the psmα mutant strain to induce skin disease, epidermal thickening and neutrophil infiltration were impaired compared with the WT and psmβ mutant strains.",S Nakagawa 2017,2017,2 genes,Nakagawa-2017-Staphylococcus aureus Virulent P,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14564,PHI:9411,UniProt,I3G603,GenBank,EIK18987,,,VRS8,psmbeta,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection,primates,9606,Homo sapiens (related: human),,,,keratinocyte,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29120744,PubMed,10.1016/j.chom.2017.10.008,Cell Host Microbe. 2017 Nov 8;22(5):667-677.e5,yumi01@chiba-u.jp,"The ability of the psmα mutant strain to induce skin disease, epidermal thickening and neutrophil infiltration were impaired compared with the WT and psmβ mutant strains.",S Nakagawa 2017,2017,2 genes,Nakagawa-2017-Staphylococcus aureus Virulent P,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14565,PHI:9412,UniProt,A0A509AIG4,GenBank,VUC54567,,,ANKA,GEXP15 (PBANKA_0515400),chromosome 5,,,PP1,UniProt: A0A0Y9XAE0; GenBank: SCM17954,,5821,Plasmodium berghei,,,cerebral malaria,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood,Plasmodium specific protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31348803,PubMed,10.1371/journal.ppat.1007973,PLoS Pathog. 2019 Jul 26;15(7):e1007973,jamal.khalife@pasteur-lille.fr,GEXP15 deficient P. berghei blood parasites showed that they were unable to develop lethal infection in BALB/c mice or to establish experimental cerebral malaria in C57BL/6 mice.,T Hollin 2019,2019,1 gene,Hollin-2019-Essential role of GEXP15 a specif,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14566,PHI:9412,UniProt,A0A509AIG4,GenBank,VUC54567,,,ANKA,GEXP15 (PBANKA_0515400),chromosome 5,,,PP1,UniProt: A0A0Y9XAE0; GenBank: SCM17954,,5821,Plasmodium berghei,,,malaria; hyperparasitemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,Plasmodium specific protein,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31348803,PubMed,10.1371/journal.ppat.1007973,PLoS Pathog. 2019 Jul 26;15(7):e1007973,jamal.khalife@pasteur-lille.fr,GEXP15 deficient P. berghei blood parasites showed that they were unable to develop lethal infection in BALB/c mice or to establish experimental cerebral malaria in C57BL/6 mice.,T Hollin 2019,2019,1 gene,Hollin-2019-Essential role of GEXP15 a specif,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14567,PHI:9413,UniProt,A0A1D8PF20,GenBank,AOW26725,,,SC5314,RTG3,chromosome 1,,,,,,5476,Candida albicans,,HBCA 16,candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,intestine,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31400863,PubMed,10.1016/j.mycmed.2019.07.003,J Mycol Med. 2019 Jul 26. pii: S1156-5233(19)30007-1,saifhameed@yahoo.co.in,RTG signaling disruption leads to inhibited biofilm formation.,S Hans 2019,2019,1 gene,Hans-2019-Retrograde signaling disruption infl,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14568,PHI:9413,UniProt,A0A1D8PF20,GenBank,AOW26725,,,SC5314,RTG3,chromosome 1,,,,,,5476,Candida albicans,,HBCA 16,candidiasis,primates,9606,Homo sapiens (related: human),,,,oral epithelial cell,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31400863,PubMed,10.1016/j.mycmed.2019.07.003,J Mycol Med. 2019 Jul 26. pii: S1156-5233(19)30007-1,saifhameed@yahoo.co.in,RTG signaling disruption leads to inhibited cell adherence to buccal epithelial cells.,S Hans 2019,2019,1 gene,Hans-2019-Retrograde signaling disruption infl,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14569,PHI:9414,UniProt,P27243,GenBank,AAA24524,,,GBGD28,rfaL (ocw),,,,,,,562,Escherichia coli,439184,RS218,bacterial sepsis; neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; kidney; liver; lung; spleen,O antigen ligase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31400443,PubMed,10.1016/j.micpath.2019.103656,Microb Pathog. 2019 Aug 7;136:103656,tanchen@mail.hzau.edu.cn,"Ocw affected the lipopolysaccharide synthesis, ROS tolerance and survival of E. coli in the host environment.",Y Zheng 2019,2019,1 gene,Zheng-2019-Effect of O antigen ligase gene mut,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14570,PHI:9414,UniProt,P27243,GenBank,AAA24524,,,GBGD28,rfaL (ocw),,,,,,,562,Escherichia coli,439184,RS218,bacterial sepsis; neonatal meningitis,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,O antigen ligase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16241,,,,,gene deletion: full; gene complementation,,,YVS,31400443,PubMed,10.1016/j.micpath.2019.103656,Microb Pathog. 2019 Aug 7;136:103656,tanchen@mail.hzau.edu.cn,Significantly lower adhesion and invasion of Δocw on HBMECs was observed.,Y Zheng 2019,2019,1 gene,Zheng-2019-Effect of O antigen ligase gene mut,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14571,PHI:9414,UniProt,P27243,GenBank,AAA24524,,,GBGD28,rfaL (ocw),,,,,,,562,Escherichia coli,439184,RS218,bacterial sepsis; neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,O antigen ligase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16241,,,,,gene deletion: full; gene complementation,,,YVS,31400443,PubMed,10.1016/j.micpath.2019.103656,Microb Pathog. 2019 Aug 7;136:103656,tanchen@mail.hzau.edu.cn,Ocw affected bacterial resistance to phagocytosis and intracellular survival.,Y Zheng 2019,2019,1 gene,Zheng-2019-Effect of O antigen ligase gene mut,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14572,PHI:9415,UniProt,P0DM78,GenBank,AAA27188,,,,phoP,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,bony fishes,7955,Danio rerio (related: zebrafish),AB/TL,,,larva,DNA-binding transcription activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31428591,PubMed,10.3389/fcimb.2019.00279,Front Cell Infect Microbiol. 2019 Aug 2;9:279,a.h.meijer@biology.leidenuniv.nl,PhoP contributed to S. Typhimurium infection establishment and virulence in the zebrafish host.,S Masud 2019,2019,5 genes,Masud-2019-Rubicon-Dependent Lc3 Recruitment t,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14573,PHI:9416,UniProt,P65882,GenBank,AAL23186,,,LT2,purA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,bony fishes,7955,Danio rerio (related: zebrafish),AB/TL,,,larva,adenylosuccinate synthetase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31428591,PubMed,10.3389/fcimb.2019.00279,Front Cell Infect Microbiol. 2019 Aug 2;9:279,a.h.meijer@biology.leidenuniv.nl,PurA contributed to S. Typhimurium infection establishment and virulence in the zebrafish host.,S Masud 2019,2019,5 genes,Masud-2019-Rubicon-Dependent Lc3 Recruitment t,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14574,PHI:9417,UniProt,Q56019,GenBank,AAA75169,,,LT2,sipB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,bony fishes,7955,Danio rerio (related: zebrafish),AB/TL,,,larva,SPI1 translocator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31428591,PubMed,10.3389/fcimb.2019.00279,Front Cell Infect Microbiol. 2019 Aug 2;9:279,a.h.meijer@biology.leidenuniv.nl,"SPI1 and SPI2 factors, SipB, and SsrB were dispensible for establishing systemic infection in zebrafish embryos.",S Masud 2019,2019,5 genes,Masud-2019-Rubicon-Dependent Lc3 Recruitment t,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14575,PHI:9418,UniProt,O54305,GenBank,CAB09344,,,,ssrB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,bony fishes,7955,Danio rerio (related: zebrafish),AB/TL,,,larva,SPI2-protein regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31428591,PubMed,10.3389/fcimb.2019.00279,Front Cell Infect Microbiol. 2019 Aug 2;9:279,a.h.meijer@biology.leidenuniv.nl,"SPI1 and SPI2 factors, SipB, and SsrB were dispensible for establishing systemic infection in zebrafish embryos.",S Masud 2019,2019,5 genes,Masud-2019-Rubicon-Dependent Lc3 Recruitment t,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14576,PHI:9419,UniProt,P0A2R2,GenBank,AAB96639,,,LT2,flhD,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,bony fishes,7955,Danio rerio (related: zebrafish),AB/TL,,,larva,flagellar transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31428591,PubMed,10.3389/fcimb.2019.00279,Front Cell Infect Microbiol. 2019 Aug 2;9:279,a.h.meijer@biology.leidenuniv.nl,Mutation of the flagellin transcriptional regulator FlhD increases virulence of S. Typhimurium in the systemically infected zebrafish host.,S Masud 2019,2019,5 genes,Masud-2019-Rubicon-Dependent Lc3 Recruitment t,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14577,PHI:9420,UniProt,J9VSP4,GenBank,AFR95644,,,H99,CNAG_02176,chromosome 6,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,uncharacterised protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31311883,PubMed,10.1128/mBio.01440-19,MBio. 2019 Jul 16;10(4). pii: e01440-19,knielsen@umn.edu,Reduced pathogenesis observed in the itr4 mutant was likely due to reduced growth in or delayed dissemination to the brain.,A C Gerstein 2019,2019,6 genes,Gerstein-2019-Identification of Pathogen Genom,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14578,PHI:9421,UniProt,J9VR25,GenBank,AFR95861,,,H99,CNAG_06574,chromosome 7,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,antiphagocytic protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31311883,PubMed,10.1128/mBio.01440-19,MBio. 2019 Jul 16;10(4). pii: e01440-19,knielsen@umn.edu,Reduced pathogenesis observed in the itr4 mutant was likely due to reduced growth in or delayed dissemination to the brain.,A C Gerstein 2019,2019,6 genes,Gerstein-2019-Identification of Pathogen Genom,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14579,PHI:9422,UniProt,J9W327,GenBank,AFR98570,,,H99,CNAG_06332,chromosome 13,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,F-box domain-containing protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31311883,PubMed,10.1128/mBio.01440-19,MBio. 2019 Jul 16;10(4). pii: e01440-19,knielsen@umn.edu,Reduced pathogenesis observed in the itr4 mutant was likely due to reduced growth in or delayed dissemination to the brain.,A C Gerstein 2019,2019,6 genes,Gerstein-2019-Identification of Pathogen Genom,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14580,PHI:9423,UniProt,J9VW71,GenBank,AFR98488,,,H99,CNAG_06986,chromosome 12,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,sugar transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31311883,PubMed,10.1128/mBio.01440-19,MBio. 2019 Jul 16;10(4). pii: e01440-19,knielsen@umn.edu,Reduced pathogenesis observed in the itr4 mutant was likely due to reduced growth in or delayed dissemination to the brain.,A C Gerstein 2019,2019,6 genes,Gerstein-2019-Identification of Pathogen Genom,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14581,PHI:9424,UniProt,J9VV44,GenBank,AFR97291,,,H99,CNAG_04922,chromosome 10,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31311883,PubMed,10.1128/mBio.01440-19,MBio. 2019 Jul 16;10(4). pii: e01440-19,knielsen@umn.edu,Reduced pathogenesis observed in the itr4 mutant was likely due to reduced growth in or delayed dissemination to the brain.,A C Gerstein 2019,2019,6 genes,Gerstein-2019-Identification of Pathogen Genom,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14582,PHI:9425,UniProt,J9VXU6,GenBank,AFR99093,,,H99,itr4 (CNAG_05662),chromosome 14,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung,inositol transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31311883,PubMed,10.1128/mBio.01440-19,MBio. 2019 Jul 16;10(4). pii: e01440-19,knielsen@umn.edu,Reduced pathogenesis observed in the itr4 mutant was likely due to reduced growth in or delayed dissemination to the brain.,A C Gerstein 2019,2019,6 genes,Gerstein-2019-Identification of Pathogen Genom,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14583,PHI:9426,UniProt,J5JC27,GenBank,EJP63618,,,ARSEF 2860,brlA (BBA_07544),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,C2H2 type master regulator of conidiophore development,,,,reduced virulence,,,yes,,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31289140,PubMed,10.1128/mSystems.00140-19,mSystems. 2019 Jul 9;4(4). pii: e00140-19,mgfeng@zju.edu.cn,The hyphae of either deletion mutant lost insect pathogenicity through normal cuticle penetration.,A X Zhang 2019,2019,2 genes,Zhang-2019-BrlA and AbaA Govern Virulence-Requ,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14584,PHI:9427,UniProt,J4WLR8,GenBank,EJP70670,,,ARSEF 2860,abaA (BBA_00300),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2861,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,conidiophore development regulator,,,,reduced virulence,,,yes,,,reduced,,increased,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31289140,PubMed,10.1128/mSystems.00140-19,mSystems. 2019 Jul 9;4(4). pii: e00140-19,mgfeng@zju.edu.cn,The hyphae of either deletion mutant lost insect pathogenicity through normal cuticle penetration.,A X Zhang 2019,2019,2 genes,Zhang-2019-BrlA and AbaA Govern Virulence-Requ,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14585,PHI:9428,UniProt,A7EXN1,GenBank,EDN94223,,,1980,SsSm1 (SS1G_10096),,,,,,,5180,Sclerotinia sclerotiorum,,FXGD2,stem rot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,cerato-platanin family protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl; SDS; Congo red; sorbitol; H2O2; carbendazim,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; carbendazim: CHEBI:3392,,,,,other evidence: transient expression,,,YVS,29576085,PubMed,10.1016/j.plantsci.2018.02.001,Plant Sci. 2018 May;270:37-46,gaozhimou@126.com,"SsSm1 silencing caused weak tolerance to NaCl, sorbitol and SDS, and the sensitivity of mutants to carbendazim was also significantly decreased.",Y Pan 2018,2018,1 gene,Pan-2018-SsSm1 a Cerato-platanin family prote,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14586,PHI:9428,UniProt,A7EXN1,GenBank,EDN94223,,,1980,SsSm1 (SS1G_10096),,,,,,,5180,Sclerotinia sclerotiorum,,FXGD2,stem rot,eudicots,3708,Brassica napus (related: rape),,,,leaf,cerato-platanin family protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl; SDS; Congo red; sorbitol; H2O2; carbendazim,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; carbendazim: CHEBI:3392,,,,,altered gene expression / gene regulation: silencing,,,YVS,29576085,PubMed,10.1016/j.plantsci.2018.02.001,Plant Sci. 2018 May;270:37-46,gaozhimou@126.com,"SsSm1 silencing caused weak tolerance to NaCl, sorbitol and SDS, and the sensitivity of mutants to carbendazim was also significantly decreased.",Y Pan 2018,2018,1 gene,Pan-2018-SsSm1 a Cerato-platanin family prote,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14587,PHI:9428,UniProt,A7EXN1,GenBank,EDN94223,,,1980,SsSm1 (SS1G_10096),,,,,,,5180,Sclerotinia sclerotiorum,,FXGD2,stem rot,eudicots,3847,Glycine max (related: soybean),,,,leaf,cerato-platanin family protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,NaCl; SDS; Congo red; sorbitol; H2O2; carbendazim,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; carbendazim: CHEBI:3392,,,,,altered gene expression / gene regulation: silencing,,,YVS,29576085,PubMed,10.1016/j.plantsci.2018.02.001,Plant Sci. 2018 May;270:37-46,gaozhimou@126.com,"SsSm1 silencing caused weak tolerance to NaCl, sorbitol and SDS, and the sensitivity of mutants to carbendazim was also significantly decreased.",Y Pan 2018,2018,1 gene,Pan-2018-SsSm1 a Cerato-platanin family prote,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14588,PHI:9429,UniProt,Q63QH7,GenBank,CAH37057,,,K96243,ltgG (BPSL3046),chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung,lytic transglycosylase,,,,reduced virulence,,,,,,,,aberrant,,no,carbenicillin; ceftazidime,carbenicillin: CHEBI:3393; ceftazidime: CHEBI:3508,,,,,gene deletion: full; gene complementation,,,YVS,31363151,PubMed,10.1038/s41598-019-47483-z,Sci Rep. 2019 Jul 30;9(1):11060,gvm4@leicester.ac.uk,"LtgG was a key contributor to cellular morphology, division, motility and virulence in BALB/c mice.",C H Jenkins 2019,2019,1 gene,Jenkins-2019-The lytic transglycosylase LtgG,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14589,PHI:9430,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,cystic fibrosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,quorum sensing regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14590,PHI:9430,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,cystic fibrosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,quorum sensing regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14591,PHI:9430,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,cystic fibrosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,neutrophil,quorum sensing regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14592,PHI:9430,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,cystic fibrosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,neutrophil,quorum sensing regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14593,PHI:9431,UniProt,P14756,GenBank,AE004791_8,,,PAO1,lasB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,cystic fibrosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,elastase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14594,PHI:9432,UniProt,P54292,GenBank,AAC44036,,,PAO1,rhlR,chromosome 1,,,,,,287,Pseudomonas aeruginosa,652611,PA14,cystic fibrosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14595,PHI:9433,,no data found,GenBank,QDL04481,,,AZPAE15042,pqsR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,cystic fibrosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14596,PHI:9430,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,cystic fibrosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,quorum sensing regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14597,PHI:9432,UniProt,P54292,GenBank,AAC44036,,,PAO1,rhlR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,cystic fibrosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14598,PHI:9430,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,cystic fibrosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,quorum sensing regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14599,PHI:9433,,no data found,GenBank,QDL04481,,,AZPAE15042,pqsR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,cystic fibrosis,primates,9606,Homo sapiens (related: human),,,,neutrophil,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31379861,PubMed,10.3389/fimmu.2019.01670,Front Immunol. 2019 Jul 18;10:1670,william.f.c.rigby@dartmouth.edu,"LasR-deficient P. aeruginosa strains failed to induce robust NET formation in both human and murine neutrophils, independently of bacterial motility or LPS expression.",S Skopelja-Gardner 2019,2019,4 genes,Skopelja-Gardne-2019-Regulation of Pseudomonas,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14600,PHI:9434,UniProt,Q8ZRE1,GenBank,AAL19352,,,LT2,phoR,,phoR L421A,,MgtC,UniProt: D0ZLQ7; GenBank: AAD16960,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31346161,PubMed,10.1038/s41467-019-11318-2,Nat Commun. 2019 Jul 25;10(1):3326,eunjinlee@korea.ac.kr,"The removal of MgtC's effect on the ability to transport phosphate rendered Salmonella hypervirulent and decreases a non-replicating population inside macrophages, indicating that MgtC-mediated phosphate transport was required for normal Salmonella pathogenesis.",S Choi 2019,2019,4 genes,Choi-2019-The Salmonella virulence protein Mgt,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14601,PHI:9435,UniProt,D0ZLQ7,GenBank,AAD16960,,,14028s,mgtC,,,,phoR,UniProt: Q8ZRE1; GenBank: AAL19352,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,virulence protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31346161,PubMed,10.1038/s41467-019-11318-2,Nat Commun. 2019 Jul 25;10(1):3326,eunjinlee@korea.ac.kr,"The removal of MgtC's effect on the ability to transport phosphate rendered Salmonella hypervirulent and decreases a non-replicating population inside macrophages, indicating that MgtC-mediated phosphate transport was required for normal Salmonella pathogenesis.",S Choi 2019,2019,4 genes,Choi-2019-The Salmonella virulence protein Mgt,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14602,PHI:9434,UniProt,Q8ZRE1,GenBank,AAL19352,,,LT2,phoR,,phoR L421A,,MgtC,UniProt: D0ZLQ7; GenBank: AAD16960,PHI:9435,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31346161,PubMed,10.1038/s41467-019-11318-2,Nat Commun. 2019 Jul 25;10(1):3326,eunjinlee@korea.ac.kr,"The removal of MgtC's effect on the ability to transport phosphate rendered Salmonella hypervirulent and decreases a non-replicating population inside macrophages, indicating that MgtC-mediated phosphate transport was required for normal Salmonella pathogenesis.",S Choi 2019,2019,4 genes,Choi-2019-The Salmonella virulence protein Mgt,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14603,PHI:9435,UniProt,D0ZLQ7,GenBank,AAD16960,,,14028s,mgtC,,,,phoR,UniProt: Q8ZRE1; GenBank: AAL19352,PHI:9434,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,virulence protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31346161,PubMed,10.1038/s41467-019-11318-2,Nat Commun. 2019 Jul 25;10(1):3326,eunjinlee@korea.ac.kr,"The removal of MgtC's effect on the ability to transport phosphate rendered Salmonella hypervirulent and decreases a non-replicating population inside macrophages, indicating that MgtC-mediated phosphate transport was required for normal Salmonella pathogenesis.",S Choi 2019,2019,4 genes,Choi-2019-The Salmonella virulence protein Mgt,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14604,PHI:9436,UniProt,A0A0F6B941,GenBank,ACY91043,,,14028s,atpB,,phoR L421A,,,,PHI:9435,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,F0F1 ATP synthase subunit A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31346161,PubMed,10.1038/s41467-019-11318-2,Nat Commun. 2019 Jul 25;10(1):3326,eunjinlee@korea.ac.kr,"The removal of MgtC's effect on the ability to transport phosphate rendered Salmonella hypervirulent and decreases a non-replicating population inside macrophages, indicating that MgtC-mediated phosphate transport was required for normal Salmonella pathogenesis.",S Choi 2019,2019,4 genes,Choi-2019-The Salmonella virulence protein Mgt,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14605,PHI:9435,UniProt,D0ZLQ7,GenBank,AAD16960,,,14028s,mgtC,,,,phoR,UniProt: Q8ZRE1; GenBank: AAL19352,PHI:9436,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,virulence protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31346161,PubMed,10.1038/s41467-019-11318-2,Nat Commun. 2019 Jul 25;10(1):3326,eunjinlee@korea.ac.kr,"The removal of MgtC's effect on the ability to transport phosphate rendered Salmonella hypervirulent and decreases a non-replicating population inside macrophages, indicating that MgtC-mediated phosphate transport was required for normal Salmonella pathogenesis.",S Choi 2019,2019,4 genes,Choi-2019-The Salmonella virulence protein Mgt,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14606,PHI:9437,UniProt,D0ZV90,GenBank,ACY87895,,,14028s,phoB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31346161,PubMed,10.1038/s41467-019-11318-2,Nat Commun. 2019 Jul 25;10(1):3326,eunjinlee@korea.ac.kr,"The removal of MgtC's effect on the ability to transport phosphate rendered Salmonella hypervirulent and decreases a non-replicating population inside macrophages, indicating that MgtC-mediated phosphate transport was required for normal Salmonella pathogenesis.",S Choi 2019,2019,4 genes,Choi-2019-The Salmonella virulence protein Mgt,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14607,PHI:9434,UniProt,Q8ZRE1,GenBank,AAL19352,,,LT2,phoR,,phoR L421A,,MgtC,UniProt: D0ZLQ7; GenBank: AAD16960,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31346161,PubMed,10.1038/s41467-019-11318-2,Nat Commun. 2019 Jul 25;10(1):3326,eunjinlee@korea.ac.kr,"The removal of MgtC's effect on the ability to transport phosphate rendered Salmonella hypervirulent and decreases a non-replicating population inside macrophages, indicating that MgtC-mediated phosphate transport was required for normal Salmonella pathogenesis.",S Choi 2019,2019,4 genes,Choi-2019-The Salmonella virulence protein Mgt,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14608,PHI:9435,UniProt,D0ZLQ7,GenBank,AAD16960,,,14028s,mgtC,,,,phoR,UniProt: Q8ZRE1; GenBank: AAL19352,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,virulence protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31346161,PubMed,10.1038/s41467-019-11318-2,Nat Commun. 2019 Jul 25;10(1):3326,eunjinlee@korea.ac.kr,"The removal of MgtC's effect on the ability to transport phosphate rendered Salmonella hypervirulent and decreases a non-replicating population inside macrophages, indicating that MgtC-mediated phosphate transport was required for normal Salmonella pathogenesis.",S Choi 2019,2019,4 genes,Choi-2019-The Salmonella virulence protein Mgt,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14609,PHI:9437,UniProt,D0ZV90,GenBank,ACY87895,,,14028s,phoB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31346161,PubMed,10.1038/s41467-019-11318-2,Nat Commun. 2019 Jul 25;10(1):3326,eunjinlee@korea.ac.kr,"The removal of MgtC's effect on the ability to transport phosphate rendered Salmonella hypervirulent and decreases a non-replicating population inside macrophages, indicating that MgtC-mediated phosphate transport was required for normal Salmonella pathogenesis.",S Choi 2019,2019,4 genes,Choi-2019-The Salmonella virulence protein Mgt,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14610,PHI:9438,UniProt,P09545,GenBank,CAA68637,,,017,hlyA,,4-base deletion of nucleotide 1088 to 1091,,,,,666,Vibrio cholerae,1124478,El Tor C6706,cholera,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,hemolysin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31338129,PubMed,10.1186/s13099-019-0316-7,Gut Pathog. 2019 Jul 12;11:38,kanbiao@icdc.cn,Negative hemolytic phenotype resulted from the base deletion mutation of nucleotide 1088 to 1091 in hlyA genes.,Y Fan 2019,2019,1 gene,Fan-2019-Nonhemolysis of epidemic El Tor bioty,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14611,PHI:9438,UniProt,P09545,GenBank,CAA68637,,,017,hlyA,,,,,,,666,Vibrio cholerae,1124478,El Tor C6706,cholera,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,hemolysin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31338129,PubMed,10.1186/s13099-019-0316-7,Gut Pathog. 2019 Jul 12;11:38,kanbiao@icdc.cn,Negative hemolytic phenotype resulted from the base deletion mutation of nucleotide 1088 to 1091 in hlyA genes.,Y Fan 2019,2019,1 gene,Fan-2019-Nonhemolysis of epidemic El Tor bioty,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14612,PHI:9438,UniProt,P09545,GenBank,CAA68637,,,017,hlyA,,"point mutation was detected at nucleotide position 1358, causing the F453S mutation; point mutation at 1979 (C→T)",,,,,666,Vibrio cholerae,1124478,El Tor C6706,cholera,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,hemolysin A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31338129,PubMed,10.1186/s13099-019-0316-7,Gut Pathog. 2019 Jul 12;11:38,kanbiao@icdc.cn,Negative hemolytic phenotype resulted from the base deletion mutation of nucleotide 1088 to 1091 in hlyA genes.,Y Fan 2019,2019,1 gene,Fan-2019-Nonhemolysis of epidemic El Tor bioty,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14613,PHI:9439,UniProt,Q72RN4,GenBank,AAS70300,,,Fiocruz L1-130,LIC11711,chromosome I,,,,,,173,Leptospira interrogans,,serovar Copenhageni strain M20,leptospirosis,primates,9606,Homo sapiens (related: human),BALB/c,,,serum,putative lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31422744,PubMed,10.1080/21505594.2019.1650613,Virulence. 2019 Dec;10(1):734-753,ana.nascimento@butantan.gov.br,Blocking LIC11711 and LIC12587 on bacterial cells by the respective antiserum reduced leptospiral cell viability when exposed to normal human serum.,L T Kochi 2019,2019,2 genes,Kochi-2019-The interaction of two novel putati,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14614,PHI:9440,UniProt,Q72P88,GenBank,AAS71148,,,Fiocruz L1-130,LIC12587,chromosome I,,,,,,173,Leptospira interrogans,,serovar Copenhageni strain M20,leptospirosis,primates,9606,Homo sapiens (related: human),BALB/c,,,serum,putative lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31422744,PubMed,10.1080/21505594.2019.1650613,Virulence. 2019 Dec;10(1):734-753,ana.nascimento@butantan.gov.br,Blocking LIC11711 and LIC12587 on bacterial cells by the respective antiserum reduced leptospiral cell viability when exposed to normal human serum.,L T Kochi 2019,2019,2 genes,Kochi-2019-The interaction of two novel putati,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14615,PHI:9439,UniProt,Q72RN4,GenBank,AAS70300,,,Fiocruz L1-130,LIC11711,chromosome I,,,,,,173,Leptospira interrogans,,serovar Copenhageni strain M20,leptospirosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,serum,putative lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31422744,PubMed,10.1080/21505594.2019.1650613,Virulence. 2019 Dec;10(1):734-753,ana.nascimento@butantan.gov.br,Blocking LIC11711 and LIC12587 on bacterial cells by the respective antiserum reduced leptospiral cell viability when exposed to normal human serum.,L T Kochi 2019,2019,2 genes,Kochi-2019-The interaction of two novel putati,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14616,PHI:9440,UniProt,Q72P88,GenBank,AAS71148,,,Fiocruz L1-130,LIC12587,chromosome I,,,,,,173,Leptospira interrogans,,serovar Copenhageni strain M20,leptospirosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,serum,putative lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31422744,PubMed,10.1080/21505594.2019.1650613,Virulence. 2019 Dec;10(1):734-753,ana.nascimento@butantan.gov.br,Blocking LIC11711 and LIC12587 on bacterial cells by the respective antiserum reduced leptospiral cell viability when exposed to normal human serum.,L T Kochi 2019,2019,2 genes,Kochi-2019-The interaction of two novel putati,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14617,PHI:9441,UniProt,P0A0I7,GenBank,AAA26597,,,,agr,,,,,,,1280,Staphylococcus aureus,93061,NCTC 8325,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HEK-293 cell line,,,embryonic kidney cell line,accessory gene regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,31387948,PubMed,10.1074/jbc.RA119.008923,J Biol Chem. 2019 Sep 27;294(39):14289-14307,eywc@queensu.ca,"Agr mutant did not lead to cell killing, even at 500 MOI, indicating that this mutant detective strain was completely non-harmful to cells.",O A Radhi 2019,2019,1 gene,Radhi-2019-Inhibition of the ULK1 protein comp,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14618,PHI:9441,UniProt,P0A0I7,GenBank,AAA26597,,,,agr,,,,,,,1280,Staphylococcus aureus,93061,NCTC 8325,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,accessory gene regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,YVS,31387948,PubMed,10.1074/jbc.RA119.008923,J Biol Chem. 2019 Sep 27;294(39):14289-14307,eywc@queensu.ca,"Agr mutant did not lead to cell killing, even at 500 MOI, indicating that this mutant detective strain was completely non-harmful to cells.",O A Radhi 2019,2019,1 gene,Radhi-2019-Inhibition of the ULK1 protein comp,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14619,PHI:9442,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,BWP17,oral candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,candidalysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29891557,PubMed,10.4049/jimmunol.1800515,J Immunol. 2018 Jul 15;201(2):627-634,sarah.gaffen@pitt.edu,Expression of all three IL-36 cytokines was markedly reduced following infection with an ece1Δ/Δ mutant.,A H Verma 2018,2018,1 gene,Verma-2018-IL-36 and IL-1_IL-17 Drive Immunity,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14620,PHI:9442,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,ECE1Δ184-279,,,,,5476,Candida albicans,,BWP17,oral candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,buccal epithelial cell,candidalysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,29891557,PubMed,10.4049/jimmunol.1800515,J Immunol. 2018 Jul 15;201(2):627-634,sarah.gaffen@pitt.edu,Expression of all three IL-36 cytokines was markedly reduced following infection with an ece1Δ/Δ mutant.,A H Verma 2018,2018,1 gene,Verma-2018-IL-36 and IL-1_IL-17 Drive Immunity,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14621,PHI:9442,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,BWP17,oral candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,candidalysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29891557,PubMed,10.4049/jimmunol.1800515,J Immunol. 2018 Jul 15;201(2):627-634,sarah.gaffen@pitt.edu,"Host gene alteration data available for IL-1R1, IL-23R, IL-36R. Expression of all three IL-36 cytokines was markedly reduced following infection with an ece1Δ/Δ mutant.",A H Verma 2018,2018,1 gene,Verma-2018-IL-36 and IL-1_IL-17 Drive Immunity,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14622,PHI:9443,UniProt,Q5KN72,GenBank,AAW41281,,,JEC21,RAD23 (CNA07500),chromosome 1,deletion of entire rad23 gene (rad23Δ),,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,UV excision repair protein,,,nucleotide excision repair (NER) pathway,reduced virulence,,,,,,,,,,no,tunicamycin; dithiothreitol; tert-butyl-hydroperoxide; hydrogen peroxide; paraquat,tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:18320; tert-butyl-hydroperoxide: CHEBI:64090; hydrogen peroxide: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,31400407,PubMed,10.1016/j.gene.2019.144043,Gene. 2019 Oct 30;717:144043,alexander.idnurm@unimelb.edu.au,The role of RAD23 in virulence is due to its function in proteasomal-mediated protein degradation rather than NER.,S Verma 2019,2019,1 gene,Verma-2019-The dual function gene RAD23 contri,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14623,PHI:9443,UniProt,Q5KN72,GenBank,AAW41281,,,JEC21,RAD23 (CNA07500),chromosome 1,deletion of XPCB domain of rad23 gene (rad23Δ + RAD23-xpcbΔ),,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,UV excision repair protein,,,nucleotide excision repair (NER) pathway,unaffected pathogenicity,,,,,,,,,,no,tunicamycin; dithiothreitol; tert-butyl-hydroperoxide; hydrogen peroxide; paraquat,tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:18320; tert-butyl-hydroperoxide: CHEBI:64090; hydrogen peroxide: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: partial; gene complementation,,,YVS,31400407,PubMed,10.1016/j.gene.2019.144043,Gene. 2019 Oct 30;717:144043,alexander.idnurm@unimelb.edu.au,The role of RAD23 in virulence is due to its function in proteasomal-mediated protein degradation rather than NER.,S Verma 2019,2019,1 gene,Verma-2019-The dual function gene RAD23 contri,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14624,PHI:9443,UniProt,Q5KN72,GenBank,AAW41281,,,JEC21,RAD23 (CNA07500),chromosome 1,deletion of UBL domain of rad23 gene (rad23Δ + RAD23-ublΔ),,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,UV excision repair protein,,,nucleotide excision repair (NER) pathway,unaffected pathogenicity,,,,,,,,,,no,tunicamycin; dithiothreitol; tert-butyl-hydroperoxide; hydrogen peroxide; paraquat,tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:18320; tert-butyl-hydroperoxide: CHEBI:64090; hydrogen peroxide: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: partial; gene complementation,,,YVS,31400407,PubMed,10.1016/j.gene.2019.144043,Gene. 2019 Oct 30;717:144043,alexander.idnurm@unimelb.edu.au,The role of RAD23 in virulence is due to its function in proteasomal-mediated protein degradation rather than NER.,S Verma 2019,2019,1 gene,Verma-2019-The dual function gene RAD23 contri,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14625,PHI:9443,UniProt,Q5KN72,GenBank,AAW41281,,,JEC21,RAD23 (CNA07500),chromosome 1,deletion of UBA1 domain of rad23 gene (rad23Δ + RAD23-uba1Δ),,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,UV excision repair protein,,,nucleotide excision repair (NER) pathway,unaffected pathogenicity,,,,,,,,,,no,tunicamycin; dithiothreitol; tert-butyl-hydroperoxide; hydrogen peroxide; paraquat,tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:18320; tert-butyl-hydroperoxide: CHEBI:64090; hydrogen peroxide: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: partial; gene complementation,,,YVS,31400407,PubMed,10.1016/j.gene.2019.144043,Gene. 2019 Oct 30;717:144043,alexander.idnurm@unimelb.edu.au,The role of RAD23 in virulence is due to its function in proteasomal-mediated protein degradation rather than NER.,S Verma 2019,2019,1 gene,Verma-2019-The dual function gene RAD23 contri,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14626,PHI:9443,UniProt,Q5KN72,GenBank,AAW41281,,,JEC21,RAD23 (CNA07500),chromosome 1,deletion of UBA1 and UBL domain of rad23 gene (rad23Δ + RAD23-ublΔ + uba1Δ),,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,UV excision repair protein,,,nucleotide excision repair (NER) pathway,unaffected pathogenicity,,,,,,,,,,no,tunicamycin; dithiothreitol; tert-butyl-hydroperoxide; hydrogen peroxide; paraquat,tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:18320; tert-butyl-hydroperoxide: CHEBI:64090; hydrogen peroxide: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: partial; gene complementation,,,YVS,31400407,PubMed,10.1016/j.gene.2019.144043,Gene. 2019 Oct 30;717:144043,alexander.idnurm@unimelb.edu.au,The role of RAD23 in virulence is due to its function in proteasomal-mediated protein degradation rather than NER.,S Verma 2019,2019,1 gene,Verma-2019-The dual function gene RAD23 contri,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14627,PHI:9443,UniProt,Q5KN72,GenBank,AAW41281,,,JEC21,RAD23 (CNA07500),chromosome 1,deletion of UBA2 domain of rad23 gene (rad23Δ + RAD23-uba2Δ),,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,UV excision repair protein,,,nucleotide excision repair (NER) pathway,reduced virulence,,,,,,,,,,no,tunicamycin; dithiothreitol; tert-butyl-hydroperoxide; hydrogen peroxide; paraquat,tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:18320; tert-butyl-hydroperoxide: CHEBI:64090; hydrogen peroxide: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: partial; gene complementation,,,YVS,31400407,PubMed,10.1016/j.gene.2019.144043,Gene. 2019 Oct 30;717:144043,alexander.idnurm@unimelb.edu.au,The role of RAD23 in virulence is due to its function in proteasomal-mediated protein degradation rather than NER.,S Verma 2019,2019,1 gene,Verma-2019-The dual function gene RAD23 contri,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14628,PHI:9443,UniProt,Q5KN72,GenBank,AAW41281,,,JEC21,RAD23 (CNA07500),chromosome 1,deletion of UBA1 and UBA2 domains of rad23 gene (rad23Δ + RAD23-uba1Δ + uba2Δ),,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,UV excision repair protein,,,nucleotide excision repair (NER) pathway,reduced virulence,,,,,,,,,,no,tunicamycin; dithiothreitol; tert-butyl-hydroperoxide; hydrogen peroxide; paraquat,tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:18320; tert-butyl-hydroperoxide: CHEBI:64090; hydrogen peroxide: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: partial; gene complementation,,,YVS,31400407,PubMed,10.1016/j.gene.2019.144043,Gene. 2019 Oct 30;717:144043,alexander.idnurm@unimelb.edu.au,The role of RAD23 in virulence is due to its function in proteasomal-mediated protein degradation rather than NER.,S Verma 2019,2019,1 gene,Verma-2019-The dual function gene RAD23 contri,BATCH_095,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14629,PHI:9444,UniProt,J4VZT4,GenBank,EJP63790,,,ARSEF 2860,Bbakr1 (XP_008600433.1),,,,,,,176275,Beauveria bassiana,,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,aldo/keto reductase,,,,unaffected pathogenicity,,,,,,reduced,,,reduced,no,H2O2; NaCl; Cr(NO3)3; Congo red,"H2O2: CAS:7722-84-1; NaCl: CHEBI:26710, 3; Cr(NO3): CHEBI:86204; Congo red (CR): CHEBI:34653",,,,,gene disruption; gene complementation,,,YVS,29305969,PubMed,10.1016/j.fgb.2018.01.001,Fungal Genet Biol. 2018 Feb;111:7-15,yjzhang@swu.edu.cn,"Little effect on virulence was seen for either the ΔBbakr1 or overexpression strains in insect bioassays via cuticle infection or intrahemocoel injection assays, suggesting that Bbakr1 is not required for virulence.",H Wang 2018,2018,1 gene,"Wang-2018-An aldo-keto reductase, Bbakr1, is i",BATCH_096A,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14630,PHI:9444,UniProt,J4VZT4,GenBank,EJP63790,,,ARSEF 2860,Bbakr1 (XP_008600433.1),,,,,,,176275,Beauveria bassiana,,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,aldo/keto reductase,,,,unaffected pathogenicity,,,,,,reduced,,,reduced,no,H2O2; NaCl; Cr(NO3)3; Congo red,"H2O2: CAS:7722-84-1; NaCl: CHEBI:26710, 3; Cr(NO3): CHEBI:86204; Congo red (CR): CHEBI:34653",,,,,altered gene expression / gene regulation: overexpression,,,YVS,29305969,PubMed,10.1016/j.fgb.2018.01.001,Fungal Genet Biol. 2018 Feb;111:7-15,yjzhang@swu.edu.cn,"Little effect on virulence was seen for either the ΔBbakr1 or overexpression strains in insect bioassays via cuticle infection or intrahemocoel injection assays, suggesting that Bbakr1 is not required for virulence.",H Wang 2018,2018,1 gene,"Wang-2018-An aldo-keto reductase, Bbakr1, is i",BATCH_096A,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14631,PHI:9445,UniProt,G7SDV6,GenBank,AER19030,,,D12,PrsA,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,parvulin-type peptidyl-prolyl isomerase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31500724,PubMed,10.1016/j.vetmic.2019.07.027,Vet Microbiol. 2019 Sep;236:108375,whfang@zju.edu.cn,PrsA did not have direct involvement in cell adhesion.,H Liu 2019,2019,1 gene,Liu-2019-PrsA contributes to Streptococcus sui,BATCH_096A,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14632,PHI:9445,UniProt,G7SDV6,GenBank,AER19030,,,D12,PrsA,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),bEnd.3 cell line,,,brain microvascular endothelial cell line,parvulin-type peptidyl-prolyl isomerase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31500724,PubMed,10.1016/j.vetmic.2019.07.027,Vet Microbiol. 2019 Sep;236:108375,whfang@zju.edu.cn,PrsA did not have direct involvement in cell adhesion.,H Liu 2019,2019,1 gene,Liu-2019-PrsA contributes to Streptococcus sui,BATCH_096A,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14633,PHI:9445,UniProt,G7SDV6,GenBank,AER19030,,,D12,PrsA,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage cell line,parvulin-type peptidyl-prolyl isomerase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31500724,PubMed,10.1016/j.vetmic.2019.07.027,Vet Microbiol. 2019 Sep;236:108375,whfang@zju.edu.cn,Deletion of prsA rendered the bacteria more susceptible to phagocytic killing.,H Liu 2019,2019,1 gene,Liu-2019-PrsA contributes to Streptococcus sui,BATCH_096A,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14634,PHI:9445,UniProt,G7SDV6,GenBank,AER19030,,,D12,PrsA,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,parvulin-type peptidyl-prolyl isomerase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31500724,PubMed,10.1016/j.vetmic.2019.07.027,Vet Microbiol. 2019 Sep;236:108375,whfang@zju.edu.cn,Survival of ΔprsA was significantly reduced in blood.,H Liu 2019,2019,1 gene,Liu-2019-PrsA contributes to Streptococcus sui,BATCH_096A,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14635,PHI:9445,UniProt,G7SDV6,GenBank,AER19030,,,D12,PrsA,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,parvulin-type peptidyl-prolyl isomerase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31500724,PubMed,10.1016/j.vetmic.2019.07.027,Vet Microbiol. 2019 Sep;236:108375,whfang@zju.edu.cn,PrsA deletion led to attenuated virulence of S. suis 2 in mice.,H Liu 2019,2019,1 gene,Liu-2019-PrsA contributes to Streptococcus sui,BATCH_096A,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14636,PHI:9446,UniProt,P95844,GenBank,AAP42796,,,ATCC 25904; NCTC 10833,sigB,,,,,,,1280,Staphylococcus aureus,273036,RF122,bovine mastitis,rodents,10090,Mus musculus (related: house mouse),CF1,,,,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31530887,PubMed,10.1038/s41598-019-49981-6,Sci Rep. 2019 Sep 17;9(1):13479,tom.grunert@vetmeduni.ac.at,"No diferences were seen in internalization, persistence or binding to fibronectin between SigB-defcient variants.",H Marbach 2019,2019,1 gene,Marbach-2019-Within-host evolution of bovine S,BATCH_096A,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14637,PHI:9446,UniProt,P95844,GenBank,AAP42796,,,ATCC 25904; NCTC 10833,sigB,,,,,,,1280,Staphylococcus aureus,273036,RF122,bovine mastitis,even-toed ungulates,9913,Bos taurus (related: cattle),MAC-T cell line,,,,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31530887,PubMed,10.1038/s41598-019-49981-6,Sci Rep. 2019 Sep 17;9(1):13479,tom.grunert@vetmeduni.ac.at,"No diferences were seen in internalization, persistence or binding to fibronectin between SigB-defcient variants.",H Marbach 2019,2019,1 gene,Marbach-2019-Within-host evolution of bovine S,BATCH_096A,2019-09-01,MC,,,,,,,,,,,,,
,,Record 14638,PHI:9447,UniProt,Q7A5Q2,GenBank,BAB42481,,,N315,PstS,,,,,,PHI:9448; PHI:9449; PHI:9450,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,phosphate-binding protein/ thioredoxine reductase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14639,PHI:9448,,no data found,GenBank,VFS05436,,,NCTC8532,PstC,,,,,,PHI:9447; PHI:9449; PHI:9450,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,"ABC-type phosphate transport system, permease component",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14640,PHI:9449,,no data found,GenBank,KFL07504,,,CDC 73-57501,PstA,,,,,,PHI:9447; PHI:9448; PHI:9450,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,"phosphate ABC transporter, permease protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14641,PHI:9450,UniProt,Q2FYQ0,GenBank,ABD30480,,,NCTC 8325,PstB,,,,,,PHI:9447; PHI:9448; PHI:9449,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,phosphate import ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14642,PHI:9451,UniProt,A0A2S6D5Q7,GenBank,PPJ74719,,,G703N2B1,PitA,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,inorganic phosphate transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14643,PHI:9452,UniProt,A0A0H2JIX0,GenBank,GBV19690,,,M1K003,NptA,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,Na+/phosphate symporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14644,PHI:9447,UniProt,Q7A5Q2,GenBank,BAB42481,,,N315,PstS,,,,,,PHI:9448; PHI:9449; PHI:9450; PHI:9451,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,phosphate-binding protein/ thioredoxine reductase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14645,PHI:9448,,no data found,GenBank,VFS05436,,,NCTC8532,PstC,,,,,,PHI:9447; PHI:9449; PHI:9450; PHI:9451,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,"ABC-type phosphate transport system, permease component",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14646,PHI:9449,,no data found,GenBank,KFL07504,,,CDC 73-57501,PstA,,,,,,PHI:9447; PHI:9448; PHI:9450; PHI:9451,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,"phosphate ABC transporter, permease protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14647,PHI:9450,UniProt,Q2FYQ0,GenBank,ABD30480,,,NCTC 8325,PstB,,,,,,PHI:9447; PHI:9448; PHI:9449; PHI:9451,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,phosphate import ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14648,PHI:9451,UniProt,A0A2S6D5Q7,GenBank,PPJ74719,,,G703N2B1,PitA,,,,,,PHI:9447; PHI:9448; PHI:9449; PHI:9450,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,inorganic phosphate transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14649,PHI:9447,UniProt,Q7A5Q2,GenBank,BAB42481,,,N315,PstS,,,,,,PHI:9448; PHI:9449; PHI:9450; PHI:9452,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,phosphate-binding protein/ thioredoxine reductase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14650,PHI:9448,,no data found,GenBank,VFS05436,,,NCTC8532,PstC,,,,,,PHI:9447; PHI:9449; PHI:9450; PHI:9452,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,"ABC-type phosphate transport system, permease component",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14651,PHI:9449,,no data found,GenBank,KFL07504,,,CDC 73-57501,PstA,,,,,,PHI:9447; PHI:9448; PHI:9450; PHI:9452,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,"phosphate ABC transporter, permease protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14652,PHI:9450,UniProt,Q2FYQ0,GenBank,ABD30480,,,NCTC 8325,PstB,,,,,,PHI:9447; PHI:9448; PHI:9449; PHI:9452,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,phosphate import ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14653,PHI:9452,UniProt,A0A0H2JIX0,GenBank,GBV19690,,,M1K003,NptA,,,,,,PHI:9447; PHI:9448; PHI:9449; PHI:9450,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,Na+/phosphate symporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14654,PHI:9452,UniProt,A0A0H2JIX0,GenBank,GBV19690,,,M1K003,NptA,,,,,,PHI:9451,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,Na+/phosphate symporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14655,PHI:9451,UniProt,A0A2S6D5Q7,GenBank,PPJ74719,,,G703N2B1,PitA,,,,,,PHI:9452,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; heart; kidney,inorganic phosphate transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29084897,PubMed,10.1128/IAI.00631-17,Infect Immun. 2017 Dec 19;86(1). pii: e00631-17,kehlfie@illinois.edu,Inorganic phosphate uptake by S. aureus differs from established models and that acquisition of a third transporter enhances the ability of the bacterium to cause infection,J L Kelliher 2017,2017,6 genes,Kelliher-2017-Acquisition of the phosphate tra,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14656,PHI:9453,UniProt,G1XP67,GenBank,EGX45134,,,ATCC 24927,AoSlt2 (XP_011126279),,,,,,,2813651,Orbilia oligospora,756982,CBS 115.81,nematode trapping fungus,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,mitogen-activated protein (MAP) kinase,,,,loss of pathogenicity,,,,,,reduced,,reduced,,no,sodium dodecyl sulfate; Congo red; H2O2; menadione; NaCl; sorbitol,SDS: CHEBI:8984; Congo red (CR): CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,YVS,29702229,PubMed,10.1016/j.fgb.2018.04.011,Fungal Genet Biol. 2018 Jul;116:42-50,jinkui960@ynu.edu.cn,"Disruption of AoSlt2 and MhSlt2 led to reduced mycelial growth, increased sensitivity to environmental stresses. Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.",Z Zhen 2018,2018,2 genes,Zhen-2018-MAP kinase Slt2 orthologs play simil,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14657,PHI:9454,UniProt,S8A502,GenBank,EPS36201,,,CBS 200.50,MhSlt2 (XP_011115715),,,,,,,430498,Dactylellina haptotyla,1284197,CBS 200.50,nematode trapping fungus,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,mitogen-activated protein (MAP) kinase,,,,loss of pathogenicity,,,,,,reduced,,reduced,,no,sodium dodecyl sulfate; Congo red; H2O2; menadione; NaCl; sorbitol,SDS: CHEBI:8984; Congo red (CR): CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,YVS,29702229,PubMed,10.1016/j.fgb.2018.04.011,Fungal Genet Biol. 2018 Jul;116:42-50,jinkui960@ynu.edu.cn,"Disruption of AoSlt2 and MhSlt2 led to reduced mycelial growth, increased sensitivity to environmental stresses.",Z Zhen 2018,2018,2 genes,Zhen-2018-MAP kinase Slt2 orthologs play simil,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14658,PHI:9455,,no data found,,,,,,stnc640,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain 50336,salmonellosis,birds,9031,Gallus gallus (related: chicken),,,,liver; spleen; cecum,small non-coding RNA,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31488137,PubMed,10.1186/s12917-019-2066-7,BMC Vet Res. 2019 Sep 5;15(1):319,mengxia_1@126.com,The virulence of 50336Δstnc640 was enhanced in a one-day-old chicken model of S. Enteritidis disease.,X Meng 2019,2019,1 gene,Meng-2019-Small non-coding RNA STnc640 regulat,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14659,PHI:9455,,no data found,,,,,,stnc640,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain 50336,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,small non-coding RNA,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31488137,PubMed,10.1186/s12917-019-2066-7,BMC Vet Res. 2019 Sep 5;15(1):319,mengxia_1@126.com,The adhesion ability of 50336Δstnc640 to Caco-2 cells was increased compared to the 50336 WT strain.,X Meng 2019,2019,1 gene,Meng-2019-Small non-coding RNA STnc640 regulat,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14660,PHI:9456,UniProt,G1X756,GenBank,EGX50964,,,ATCC 24927,AoVosA (AOL_s00054g700),,,,,,,2813651,Orbilia oligospora,756982,CBS 115.81,nematode trapping fungus,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,velvet family protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,reduced,no,"sodium dodecyl sulfate, Congo red, H2O2; NaCl; sorbitol; menadione",SDS: CHEBI:8984; Congo red (CR): CHEBI:34653; H2O2: CHEBI:16240; NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,31481946,PubMed,10.3389/fmicb.2019.01917,Front Microbiol. 2019 Aug 20;10:1917,jinkui960@ynu.edu.cn,"AoVelB was essential for conidiation, trap formation, and pathogenicity in A. oligospora, while AoVosA played a role in the regulation of conidial germination and heat shock stress. Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.",G Zhang 2019,2019,2 genes,Zhang-2019-The Velvet Proteins VosA and VelB P,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14661,PHI:9457,UniProt,G1X7G7,GenBank,EGX51075,,,ATCC 24927,AoVelB (AOL_s00054g811),,,,,,,2813651,Orbilia oligospora,756982,CBS 115.81,nematode trapping fungus,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,velvet family protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,"sodium dodecyl sulfate, Congo red, H2O2; NaCl; sorbitol; menadione",SDS: CHEBI:8984; Congo red (CR): CHEBI:34653; H2O2: CHEBI:16240; NaCl: CHEBI:26710; D-sorbitol: CHEBI:17924; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,31481946,PubMed,10.3389/fmicb.2019.01917,Front Microbiol. 2019 Aug 20;10:1917,jinkui960@ynu.edu.cn,"AoVelB was essential for conidiation, trap formation, and pathogenicity in A. oligospora, while AoVosA played a role in the regulation of conidial germination and heat shock stress. Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.",G Zhang 2019,2019,2 genes,Zhang-2019-The Velvet Proteins VosA and VelB P,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14662,PHI:9458,UniProt,Q2FIE9,GenBank,ABD22039,,,USA300_FPR3757,lipA (SAUSA300_0829),,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,lipoic acid synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29056428,PubMed,10.1016/j.chom.2017.09.004,Cell Host Microbe. 2017 Nov 8;22(5):678-687.e9,falonzo@luc.edu,"LipA-deficient strain induces heightened pro-inflammatory cytokine production, which is diminished in the absence of TLR2.",J P Grayczyk 2017,2017,1 gene,Grayczyk-2017-A Lipoylated Metabolic Protein R,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14663,PHI:9458,UniProt,Q2FIE9,GenBank,ABD22039,,,USA300_FPR3757,lipA (SAUSA300_0829),,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,peritoneal fluid; kidney,lipoic acid synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29056428,PubMed,10.1016/j.chom.2017.09.004,Cell Host Microbe. 2017 Nov 8;22(5):678-687.e9,falonzo@luc.edu,"LipA-deficient strain induces heightened pro-inflammatory cytokine production, which is diminished in the absence of TLR2. lavage fluid; kidney",J P Grayczyk 2017,2017,1 gene,Grayczyk-2017-A Lipoylated Metabolic Protein R,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14664,PHI:9459,UniProt,P19786,GenBank,CAD05378,,,CT18,aroA,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,3-phosphoshikimate 1-carboxyvinyltransferase,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14665,PHI:9460,UniProt,Q8Z8K9,GenBank,AAO69872,,,Ty2,entA,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,"2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase",,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14666,PHI:9461,UniProt,Q8Z4H3,GenBank,AAO70240,,,Ty2,iroC,,,,,,PHI:9462; PHI:9463; PHI:9464,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,putative ABC transporter protein,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14667,PHI:9462,UniProt,Q8Z4H2,GenBank,AAO70241,,,Ty2,iroD,,,,,,PHI:9461; PHI:9463; PHI:9464,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,putative ferric enterochelin esterase,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14668,PHI:9463,UniProt,O54506,GenBank,AAO70242,,,Ty2,iroE,,,,,,PHI:9461; PHI:9462; PHI:9464,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,alpha/beta hydrolase,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14669,PHI:9464,UniProt,Q8Z4H1,GenBank,AAO70243,,,Ty2,iroN,,,,,,PHI:9461; PHI:9462; PHI:9463,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,TonB-dependent outer membrane siderophore receptor protein,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14670,PHI:9465,UniProt,Q8Z7H2,GenBank,AAO69314,,,Ty2,phoP,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,virulence transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14671,PHI:9466,UniProt,Q04976,GenBank,AAO71801,,,Ty2,vexA,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,Vi polysaccharide export protein,,,,unaffected pathogenicity,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14672,PHI:9467,UniProt,P0A1I4,GenBank,AAO70359,,,Ty2,invA,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,invasion protein,,,,unaffected pathogenicity,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14673,PHI:9468,UniProt,Q8XFU4,GenBank,AAO68911,,,Ty2,ssrB,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,DNA-binding response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14674,PHI:9469,UniProt,Q8Z6A7,GenBank,AAO68774,,,Ty2,cdtB,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,putative toxin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14675,PHI:9466,UniProt,Q04976,GenBank,AAO71801,,,Ty2,vexA,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),hu-SRC-SCID,,,liver; spleen,Vi polysaccharide export protein,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14676,PHI:9460,UniProt,Q8Z8K9,GenBank,AAO69872,,,Ty2,entA,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),hu-SRC-SCID,,,liver; spleen,"2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase",,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14677,PHI:9461,UniProt,Q8Z4H3,GenBank,AAO70240,,,Ty2,iroC,,,,,,PHI:9462; PHI:9463; PHI:9464,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),hu-SRC-SCID,,,liver; spleen,putative ABC transporter protein,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14678,PHI:9462,UniProt,Q8Z4H2,GenBank,AAO70241,,,Ty2,iroD,,,,,,PHI:9461; PHI:9463; PHI:9464,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),hu-SRC-SCID,,,liver; spleen,putative ferric enterochelin esterase,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14679,PHI:9463,UniProt,O54506,GenBank,AAO70242,,,Ty2,iroE,,,,,,PHI:9461; PHI:9462; PHI:9464,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),hu-SRC-SCID,,,liver; spleen,alpha/beta hydrolase,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14680,PHI:9464,UniProt,Q8Z4H1,GenBank,AAO70243,,,Ty2,iroN,,,,,,PHI:9461; PHI:9462; PHI:9463,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),hu-SRC-SCID,,,liver; spleen,TonB-dependent outer membrane siderophore receptor protein,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14681,PHI:9459,UniProt,P19786,GenBank,CAD05378,,,CT18,aroA,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),hu-SRC-SCID,,,liver; spleen,3-phosphoshikimate 1-carboxyvinyltransferase,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14682,PHI:9465,UniProt,Q8Z7H2,GenBank,AAO69314,,,Ty2,phoP,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),hu-SRC-SCID,,,spleen,virulence transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14683,PHI:9468,UniProt,Q8XFU4,GenBank,AAO68911,,,Ty2,ssrB,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),hu-SRC-SCID,,,liver; spleen,DNA-binding response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14684,PHI:9469,UniProt,Q8Z6A7,GenBank,AAO68774,,,Ty2,cdtB,,,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),hu-SRC-SCID,,,liver; spleen,putative toxin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,"2,2-dipyridyl","2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full,,,YVS,31447308,PubMed,10.1016/j.chom.2019.08.001,Cell Host Microbe. 2019 Sep 11;26(3):426-434.e6,fcfang@uw.edu,"Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for virulence, along with the siderophore salmochelin.",J E Karlinsey 2019,2019,11 genes,Karlinsey-2019-Genome-wide Analysis of Salmone,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14685,PHI:9470,UniProt,Q8E5R9,GenBank,CAD46555,,,NEM316,cas9,,,,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; vagina,CRISPR-associated protein-9,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31497003,PubMed,10.3389/fmicb.2019.01930,Front Microbiol. 2019 Aug 21;10:1930,kelly.doran@cuanschutz.edu,Cas9 mutants were attenuated in murine models of hematogenous meningitis and vaginal colonization and exhibited significantly decreased invasion of human brain endothelium and adherence to vaginal epithelium.,B L Spencer 2019,2019,2 genes,Spencer-2019-Cas9 Contributes to Group B Strep,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14686,PHI:9470,UniProt,Q8E5R9,GenBank,CAD46555,,,NEM316,cas9,,,,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; lung,CRISPR-associated protein-9,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31497003,PubMed,10.3389/fmicb.2019.01930,Front Microbiol. 2019 Aug 21;10:1930,kelly.doran@cuanschutz.edu,Cas9 mutants were attenuated in murine models of hematogenous meningitis and vaginal colonization and exhibited significantly decreased invasion of human brain endothelium and adherence to vaginal epithelium.,B L Spencer 2019,2019,2 genes,Spencer-2019-Cas9 Contributes to Group B Strep,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14687,PHI:9470,UniProt,Q8E5R9,GenBank,CAD46555,,,NEM316,cas9,,,,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,primates,9606,Homo sapiens (related: human),HCMEC,,,brain microvascular endothelial cell line,CRISPR-associated protein-9,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31497003,PubMed,10.3389/fmicb.2019.01930,Front Microbiol. 2019 Aug 21;10:1930,kelly.doran@cuanschutz.edu,Cas9 mutants were attenuated in murine models of hematogenous meningitis and vaginal colonization and exhibited significantly decreased invasion of human brain endothelium and adherence to vaginal epithelium.,B L Spencer 2019,2019,2 genes,Spencer-2019-Cas9 Contributes to Group B Strep,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14688,PHI:9470,UniProt,Q8E5R9,GenBank,CAD46555,,,NEM316,cas9,,,,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,primates,9606,Homo sapiens (related: human),HVEC cell line,,,vaginal epithelial cell line,CRISPR-associated protein-9,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31497003,PubMed,10.3389/fmicb.2019.01930,Front Microbiol. 2019 Aug 21;10:1930,kelly.doran@cuanschutz.edu,Cas9 mutants were attenuated in murine models of hematogenous meningitis and vaginal colonization and exhibited significantly decreased invasion of human brain endothelium and adherence to vaginal epithelium.,B L Spencer 2019,2019,2 genes,Spencer-2019-Cas9 Contributes to Group B Strep,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14689,PHI:9471,UniProt,R4Z8M6,GenBank,AIK75708,,,GBS6,ciaR,,,,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,vagina,two component system response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31497003,PubMed,10.3389/fmicb.2019.01930,Front Microbiol. 2019 Aug 21;10:1930,kelly.doran@cuanschutz.edu,CiaR contributed to GBS vaginal colonization and persistence.,B L Spencer 2019,2019,2 genes,Spencer-2019-Cas9 Contributes to Group B Strep,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14690,PHI:9472,UniProt,A0A059UDR8,GenBank,AHZ59730,,,,BEC1019,,,,,,,34373,Blumeria graminis,62690,f. sp. tritici,powdery mildew (barley),monocots,4565,Triticum aestivum (related: bread wheat),cv. Aikang 58; cv. Zhoumai 26,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,31489906,PubMed,10.3390/ijms20184376,Int J Mol Sci. 2019 Sep 6;20(18),guotiancai@henau.edu.cn,"Overexpression of BEC1019 increased wheat susceptibility to Bgt and Ggt, whereas silencing BEC1019 enhanced resistance to both biotrophic and necrotrophic pathogens.",Y Zhang 2019,2019,1 gene,Zhang-2019-The Highly Conserved Barley Powdery,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14691,PHI:9472,UniProt,A0A059UDR8,GenBank,AHZ59730,,,,BEC1019,,,,,,,29850,Gaeumannomyces graminis,,var. tritici strain LY3-21,powdery mildew (barley),monocots,4565,Triticum aestivum (related: bread wheat),cv. Aikang 58; cv. Zhoumai 26,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; other evidence: transgenic plants,,,YVS,31489906,PubMed,10.3390/ijms20184376,Int J Mol Sci. 2019 Sep 6;20(18),guotiancai@henau.edu.cn,"Overexpression of BEC1019 increased wheat susceptibility to Bgt and Ggt, whereas silencing BEC1019 enhanced resistance to both biotrophic and necrotrophic pathogens.",Y Zhang 2019,2019,1 gene,Zhang-2019-The Highly Conserved Barley Powdery,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14692,PHI:9472,UniProt,A0A059UDR8,GenBank,AHZ59730,,,,BEC1019,,,,,,,34373,Blumeria graminis,62690,f. sp. tritici,powdery mildew (barley),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transient expression,,,YVS,31489906,PubMed,10.3390/ijms20184376,Int J Mol Sci. 2019 Sep 6;20(18),guotiancai@henau.edu.cn,Full and partial sequences of BEC1019 could trigger cell death in Nicotiana benthamiana leaves.,Y Zhang 2019,2019,1 gene,Zhang-2019-The Highly Conserved Barley Powdery,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14693,PHI:9473,,no data found,GenBank,ABO12519,,,ATCC 17978,prpA (A1S_2092),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,pilin subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29891547,PubMed,10.1128/IAI.00442-18,Infect Immun. 2018 Aug 22;86(9),actisla@MiamiOH.edu,Disruption of A1S_2091 abolished surface motility and pellicle formation but significantly enhanced biofilm formation on plastic by bacteria cultured in darkness.,C R Wood 2018,2018,1 gene,Wood-2018-A light-regulated type I pilus contr,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14694,PHI:9473,,no data found,GenBank,ABO12519,,,ATCC 17978,prpA (A1S_2092),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,pilin subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,29891547,PubMed,10.1128/IAI.00442-18,Infect Immun. 2018 Aug 22;86(9),actisla@MiamiOH.edu,Disruption of A1S_2091 abolished surface motility and pellicle formation but significantly enhanced biofilm formation on plastic by bacteria cultured in darkness.,C R Wood 2018,2018,1 gene,Wood-2018-A light-regulated type I pilus contr,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14695,PHI:9474,UniProt,O13359,GenBank,AOW26534,,,SC5314,kex2,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31486049,PubMed,10.1007/s42770-019-00140-z,Braz J Microbiol. 2019 Sep 4,mstaniszewska@ch.pw.edu.pl,"Hypersensitive to Sulfone, kex2Δ/kex2Δ reduced virulence in survival.",M Staniszewska 2019,2019,1 gene,Staniszewska-2019-New antifungal 4-chloro-3-ni,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14696,PHI:9475,UniProt,E9DRL9,GenBank,EFY93897,,,CQMa 102,MapacC (MAC_00388),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,hemolymph,pH-response transcription factor,,,Pal pH signaling pathway,reduced virulence,,yes,yes,,,reduced,,,wild type,no,,,,,,,gene disruption; gene complementation,,,YVS,31471639,PubMed,10.1007/s00294-019-01032-3,Curr Genet. 2019 Aug 30,jinkai@cqu.edu.cn,"The virulence of the disruptant against a locust species was markedly attenuated due to delayed appressorium formation, repressed expression of some insect cuticle hydrolases and slowed growth in locust hemolymph.",M Zhang 2019,2019,1 gene,"Zhang-2019-MaPacC, a pH-responsive transcripti",BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14697,PHI:9476,UniProt,N4VLC7,GenBank,TDZ23299,,,104-T,CoTHR4 (Cob_04177),,,,,,,5465,Colletotrichum orbiculare,1213857,MAFF240422,anthracnose,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,threonine synthase,,,threonine biosynthesis pathway,reduced virulence,,yes,yes,,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31525401,PubMed,10.1016/j.micpath.2019.103746,Microb Pathog. 2019 Sep 13:103746,a16029@mail.ryukoku.ac.jp,The conidia produced from the threonine-treated cothr4 mutant remained attenuated in pathogenicity on cucumber cotyledons even in the presence of threonine.,K Harata 2019,2019,1 gene,Harata-2019-Threonine synthase CoTHR4 is invol,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14698,PHI:9477,UniProt,Q9I4G8,GenBank,AE004547_4,,,PA01,loxA (PA1169),,,,,,,287,Pseudomonas aeruginosa,1009714,PAK,nosocomial pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,arachidonate 15-lipoxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31474948,PubMed,10.3389/fmicb.2019.01826,Front Microbiol. 2019 Aug 14;10:1826,si-tahar@univ-tours.fr,"LoxA inhibited the expression of major chemokines (e.g., MIPs and KC) and the recruitment of key leukocytes.",E Morello 2019,2019,1 gene,Morello-2019-Pseudomonas aeruginosa Lipoxygena,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14699,PHI:9477,UniProt,Q9I4G8,GenBank,AE004547_4,,,PA01,loxA (PA1169),,,,,,,287,Pseudomonas aeruginosa,1009714,PAK,nosocomial pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,arachidonate 15-lipoxygenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,31474948,PubMed,10.3389/fmicb.2019.01826,Front Microbiol. 2019 Aug 14;10:1826,si-tahar@univ-tours.fr,"LoxA inhibited the expression of major chemokines (e.g., MIPs and KC) and the recruitment of key leukocytes.",E Morello 2019,2019,1 gene,Morello-2019-Pseudomonas aeruginosa Lipoxygena,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14700,PHI:9477,UniProt,Q9I4G8,GenBank,AE004547_4,,,PA01,loxA (PA1169),,,,,,,287,Pseudomonas aeruginosa,1009714,PAK,nosocomial pneumonia,primates,9606,Homo sapiens (related: human),NCI-H292,,,lung epithelial cell,arachidonate 15-lipoxygenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31474948,PubMed,10.3389/fmicb.2019.01826,Front Microbiol. 2019 Aug 14;10:1826,si-tahar@univ-tours.fr,No significant difference could be observed in bacterial load or in the secretion of 102 cytokines and chemokines induced by either PAK'ΔloxA or PAK'overloxA.,E Morello 2019,2019,1 gene,Morello-2019-Pseudomonas aeruginosa Lipoxygena,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14701,PHI:9478,,no data found,GenBank,NJ56_RS12465,,,,Stir-2,,,,,,,29486,Yersinia ruckeri,,SC09,infection,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,liver; spleen; kidney; macrophage,TIR domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31500298,PubMed,10.3390/ijms20184409,Int J Mol Sci. 2019 Sep 7;20(18),kywang1955@126.com,The knockout of the stir-2 gene in the Yersinia ruckeri SC09 strain affected intracellular bacterial survival but not bacterial adherence and invasion.,T Liu 2019,2019,1 gene,Liu-2019-A Yersinia ruckeri TIR Domain-Contain,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14702,PHI:9479,UniProt,Q9I6V6,GenBank,AAG03566,,,PA01,"mcpB (aer2, PA0176)",,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,insects,189513,Chrysoperla carnea (no common name found),,,,,chemoreceptor,,,Che2 pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31511598,PubMed,10.1038/s41598-019-49697-7,Sci Rep. 2019 Sep 11;9(1):13166,manzanera@ugr.es,The deletion of mcpB increased the environmental and human safety index (EHSI) of P. Aeruginosa.,C Garcia-Fontana 2019,2019,1 gene,Garcia-Fontana-2019-The involvement of McpB ch,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14703,PHI:9479,UniProt,Q9I6V6,GenBank,AAG03566,,,PA01,"mcpB (aer2, PA0176)",,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,beetles,7084,Adalia bipunctata (related: two-spotted ladybird beetle),,,,,chemoreceptor,,,Che2 pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31511598,PubMed,10.1038/s41598-019-49697-7,Sci Rep. 2019 Sep 11;9(1):13166,manzanera@ugr.es,The deletion of mcpB increased the environmental and human safety index (EHSI) of P. Aeruginosa.,C Garcia-Fontana 2019,2019,1 gene,Garcia-Fontana-2019-The involvement of McpB ch,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14704,PHI:9479,UniProt,Q9I6V6,GenBank,AAG03566,,,PA01,"mcpB (aer2, PA0176)",,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,segmented worms,6396,Eisenia fetida (related: common brandling worm),,,,,chemoreceptor,,,Che2 pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31511598,PubMed,10.1038/s41598-019-49697-7,Sci Rep. 2019 Sep 11;9(1):13166,manzanera@ugr.es,The deletion of mcpB increased the environmental and human safety index (EHSI) of P. Aeruginosa.,C Garcia-Fontana 2019,2019,1 gene,Garcia-Fontana-2019-The involvement of McpB ch,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14705,PHI:9479,UniProt,Q9I6V6,GenBank,AAG03566,,,PA01,"mcpB (aer2, PA0176)",,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,crustaceans,35525,Daphnia magna (no common name found),,,,,chemoreceptor,,,Che2 pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31511598,PubMed,10.1038/s41598-019-49697-7,Sci Rep. 2019 Sep 11;9(1):13166,manzanera@ugr.es,The deletion of mcpB increased the environmental and human safety index (EHSI) of P. Aeruginosa.,C Garcia-Fontana 2019,2019,1 gene,Garcia-Fontana-2019-The involvement of McpB ch,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14706,PHI:9479,UniProt,Q9I6V6,GenBank,AAG03566,,,PA01,"mcpB (aer2, PA0176)",,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,chemoreceptor,,,Che2 pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31511598,PubMed,10.1038/s41598-019-49697-7,Sci Rep. 2019 Sep 11;9(1):13166,manzanera@ugr.es,The deletion of mcpB increased the environmental and human safety index (EHSI) of P. Aeruginosa.,C Garcia-Fontana 2019,2019,1 gene,Garcia-Fontana-2019-The involvement of McpB ch,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14707,PHI:9479,UniProt,Q9I6V6,GenBank,AAG03566,,,PA01,"mcpB (aer2, PA0176)",,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4072,Capsicum annuum (no common name found),cv. Maor,,,,chemoreceptor,,,Che2 pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31511598,PubMed,10.1038/s41598-019-49697-7,Sci Rep. 2019 Sep 11;9(1):13166,manzanera@ugr.es,The deletion of mcpB increased the environmental and human safety index (EHSI) of P. Aeruginosa.,C Garcia-Fontana 2019,2019,1 gene,Garcia-Fontana-2019-The involvement of McpB ch,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14708,PHI:9480,UniProt,A0A063C6H4,GenBank,GAO15831,,,IPU010,UvPmk1 (KDB_16903.1),,,,,,PHI:9481,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,CMGC kinase,,,MAPK signaling pathways,reduced virulence,,,,yes,,reduced,,wild type,,no,NaCl; sorbitol; calcofluor white; Congo red; SDS; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31489464,PubMed,10.1007/s00294-019-01029-y,Curr Genet. 2019 Sep 5,junbinhuang@mail.hzau.edu.cn,"Both UvPmk1 and UvCDC2 knockout mutants showed increases in tolerance to hyperosmotic and cell wall stresses, but they, respectively, exhibited decreases and increases in tolerance to oxidative stress compared with the wild-type strain HWD-2.",J Tang 2019,2019,2 genes,Tang-2019-Two protein kinases UvPmk1 and UvCDC,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14709,PHI:9481,UniProt,A0A063BQI0,GenBank,GAO15002,,,IPU010,UvCDC2 (KDB_12816.1),,,,,,PHI:9480,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,CMGC kinase,,,MAPK signaling pathways,reduced virulence,,,,yes,,reduced,,wild type,,no,NaCl; sorbitol; calcofluor white; Congo red; SDS; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31489464,PubMed,10.1007/s00294-019-01029-y,Curr Genet. 2019 Sep 5,junbinhuang@mail.hzau.edu.cn,"Both UvPmk1 and UvCDC2 knockout mutants showed increases in tolerance to hyperosmotic and cell wall stresses, but they, respectively, exhibited decreases and increases in tolerance to oxidative stress compared with the wild-type strain HWD-2.",J Tang 2019,2019,2 genes,Tang-2019-Two protein kinases UvPmk1 and UvCDC,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14710,PHI:9482,UniProt,G4NI28,GenBank,EHA47888,,,70-15,Spf1 (MGG_12005),chromosome 6,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,P5-type ATPase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,tunicamycin; dithiothreitol; H2O2; paraquat; NaCl; CaCl2; sorbitol,tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:17456; H2O2: CHEBI:16240; paraquat: CHEBI:34905; NaCl: CHEBI:26710; CaCl2: CHEBI:3312; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,31471638,PubMed,10.1007/s00294-019-01030-5,Curr Genet. 2019 Aug 30,fuchenglin@zju.edu.cn,"SPF1 was involved in some basal ER mechanisms of P. oryzae including UPR pathway and responses to ER related stresses, therefore, affecting fungal development and virulence.",Y Qu 2019,2019,1 gene,Qu-2019-The P5-type ATPase Spf1 is required fo,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14711,PHI:9482,UniProt,G4NI28,GenBank,EHA47888,,,70-15,Spf1 (MGG_12005),chromosome 6,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,P5-type ATPase,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,reduced,no,tunicamycin; dithiothreitol; H2O2; paraquat; NaCl; CaCl2; sorbitol,tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:17456; H2O2: CHEBI:16240; paraquat: CHEBI:34905; NaCl: CHEBI:26710; CaCl2: CHEBI:3312; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,31471638,PubMed,10.1007/s00294-019-01030-5,Curr Genet. 2019 Aug 30,fuchenglin@zju.edu.cn,"SPF1 was involved in some basal ER mechanisms of P. oryzae including UPR pathway and responses to ER related stresses, therefore, affecting fungal development and virulence.",Y Qu 2019,2019,1 gene,Qu-2019-The P5-type ATPase Spf1 is required fo,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14712,PHI:9483,UniProt,A7U5T7,,,,,,malR (bpsr4),,,,,,,28450,Burkholderia pseudomallei,,Bp82,melioidosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,polyketide (PK) biosynthetic gene,,,malleilactone biosynthesis,reduced virulence,,,,,,,,,,no,trimethoprim; sulfamethoxazole; ceftazidime; piperacillin; ciprofloxacin; imipenem; polymyxin B; kanamycin; paraquat,trimethoprim: CHEBI:45924; sulfamethoxazole: CHEBI:9332; ceftazidime: CHEBI:3508; piperacillin: CHEBI:8232; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; polymyxin B: CHEBI:8309; kanamycin: CHEBI:6104; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,29735757,PubMed,10.1128/JB.00008-18,J Bacteriol. 2018 Jun 25;200(14). pii: e00008-18,jrchandler@ku.edu,MalR and the mal genes contributed to the ability of B. pseudomallei to kill Caenorhabditis elegans.,J R Klaus 2018,2018,2 genes,Klaus-2018-Malleilactone is a Burkholderia pse,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14713,PHI:9484,,no data found,,,,,,malF,,,,,,,28450,Burkholderia pseudomallei,,Bp82,melioidosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,"maltose/maltodextrin ABC transporter, permease protein MalF",,,malleilactone biosynthesis,reduced virulence,,,,,,,,,,no,trimethoprim; sulfamethoxazole; ceftazidime; piperacillin; ciprofloxacin; imipenem; polymyxin B; kanamycin; paraquat,trimethoprim: CHEBI:45924; sulfamethoxazole: CHEBI:9332; ceftazidime: CHEBI:3508; piperacillin: CHEBI:8232; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; polymyxin B: CHEBI:8309; kanamycin: CHEBI:6104; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,29735757,PubMed,10.1128/JB.00008-18,J Bacteriol. 2018 Jun 25;200(14). pii: e00008-18,jrchandler@ku.edu,MalR and the mal genes contributed to the ability of B. pseudomallei to kill Caenorhabditis elegans.,J R Klaus 2018,2018,2 genes,Klaus-2018-Malleilactone is a Burkholderia pse,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14714,PHI:9485,UniProt,F9FUE8,GenBank,EGU79444,,,Fo5176,Foatg3,,,,,,,5507,Fusarium oxysporum,,,Fusarium wilt,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full,,,YVS,31466418,PubMed,10.3390/genes10090658,Genes (Basel). 2019 Aug 28;10(9). pii: E658,renmaozhi@cqu.edu.cn,A significant reduction in conidiation and hyphal growth was shown by the Foatg3Δ strains resulting in loss of virulence on potato tubers.,A R Khalid 2019,2019,1 gene,Khalid-2019-Autophagy Related Gene (ATG3) is a,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14715,PHI:9485,UniProt,F9FUE8,GenBank,EGU79444,,,Fo5176,Foatg3,,,,,,,5507,Fusarium oxysporum,,,Fusarium wilt,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,autophagy-related protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31466418,PubMed,10.3390/genes10090658,Genes (Basel). 2019 Aug 28;10(9). pii: E658,renmaozhi@cqu.edu.cn,A significant reduction in conidiation and hyphal growth was shown by the Foatg3Δ strains resulting in loss of virulence on potato tubers.,A R Khalid 2019,2019,1 gene,Khalid-2019-Autophagy Related Gene (ATG3) is a,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14716,PHI:9486,UniProt,Q99ZW2,GenBank,AAK33936,,,SF370,cas9,,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,primates,9606,Homo sapiens (related: human),,,,blood,CRISPR-associated endonuclease,,,,reduced virulence,,,,,,,,reduced,,no,vancomycin; penicillin,vancomycin: CHEBI:28001; penicillin: CHEBI:17334,,,,,gene deletion: full; gene complementation,,,YVS,31507572,PubMed,10.3389/fmicb.2019.01967,Front Microbiol. 2019 Aug 22;10:1967,valderrama@ucsd.edu,"Cas9 was required for efficient GAS adherence to epithelial cells, growth in human blood, and full virulence in a murine skin infection model.",N J Gao 2019,2019,1 gene,Gao-2019-Functional and Proteomic Analysis of,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14717,PHI:9486,UniProt,Q99ZW2,GenBank,AAK33936,,,SF370,cas9,,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,CRISPR-associated endonuclease,,,,reduced virulence,,,,,,,,reduced,,no,vancomycin; penicillin,vancomycin: CHEBI:28001; penicillin: CHEBI:17334,,,,,gene deletion: full; gene complementation,,,YVS,31507572,PubMed,10.3389/fmicb.2019.01967,Front Microbiol. 2019 Aug 22;10:1967,valderrama@ucsd.edu,"Cas9 was required for efficient GAS adherence to epithelial cells, growth in human blood, and full virulence in a murine skin infection model.",N J Gao 2019,2019,1 gene,Gao-2019-Functional and Proteomic Analysis of,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14718,PHI:9486,UniProt,Q99ZW2,GenBank,AAK33936,,,SF370,cas9,,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin,CRISPR-associated endonuclease,,,,reduced virulence,,,,,,,,reduced,,no,vancomycin; penicillin,vancomycin: CHEBI:28001; penicillin: CHEBI:17334,,,,,gene deletion: full; gene complementation,,,YVS,31507572,PubMed,10.3389/fmicb.2019.01967,Front Microbiol. 2019 Aug 22;10:1967,valderrama@ucsd.edu,"Cas9 was required for efficient GAS adherence to epithelial cells, growth in human blood, and full virulence in a murine skin infection model.",N J Gao 2019,2019,1 gene,Gao-2019-Functional and Proteomic Analysis of,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14719,PHI:9487,UniProt,E9EDR6,GenBank,EFY85931,,,CQMa 102,MaChsI (XP_007814354.1),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,,chitin synthase I,,,,unaffected pathogenicity,,no,,,,reduced,,wild type,reduced,no,Congo red; calcofluor white; H2O2; SDS; sorbitol; NaCl,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31461507,PubMed,10.1371/journal.ppat.1007964,PLoS Pathog. 2019 Aug 28;15(8):e1007964,yuxianxia@cqu.edu.cn,"Inactivation of MaChsIII, MaChsV, or MaChsVII impaired appressorium formation, affected growth of in insecta produced hyphal bodies, and altered the surface properties of conidia and hyphal bodies, resulting in defects in the ability of the mutant strains to evade insect immune responses.",J Zhang 2019,2019,7 genes,Zhang-2019-Members of chitin synthase family i,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14720,PHI:9488,UniProt,E9EE69,GenBank,EFY85782,,,CQMa 102,MaChsII (XP_007814507.1),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,,chitin synthase II,,,,unaffected pathogenicity,,no,,,,reduced,,wild type,increased,no,Congo red; calcofluor white; H2O2; SDS; sorbitol; NaCl,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31461507,PubMed,10.1371/journal.ppat.1007964,PLoS Pathog. 2019 Aug 28;15(8):e1007964,yuxianxia@cqu.edu.cn,"Inactivation of MaChsIII, MaChsV, or MaChsVII impaired appressorium formation, affected growth of in insecta produced hyphal bodies, and altered the surface properties of conidia and hyphal bodies, resulting in defects in the ability of the mutant strains to evade insect immune responses.",J Zhang 2019,2019,7 genes,Zhang-2019-Members of chitin synthase family i,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14721,PHI:9489,UniProt,E9ECB5,GenBank,EFY86435,,,CQMa 102,MaChsIV (XP_007813853.1),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,,class IV chitin synthase,,,,unaffected pathogenicity,,no,,,,reduced,,wild type,reduced,no,Congo red; calcofluor white; H2O2; SDS; sorbitol; NaCl,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31461507,PubMed,10.1371/journal.ppat.1007964,PLoS Pathog. 2019 Aug 28;15(8):e1007964,yuxianxia@cqu.edu.cn,"Inactivation of MaChsIII, MaChsV, or MaChsVII impaired appressorium formation, affected growth of in insecta produced hyphal bodies, and altered the surface properties of conidia and hyphal bodies, resulting in defects in the ability of the mutant strains to evade insect immune responses.",J Zhang 2019,2019,7 genes,Zhang-2019-Members of chitin synthase family i,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14722,PHI:9490,UniProt,E9EFH8,GenBank,EFY85326,,,CQMa 102,MaChsVI (XP_007814966.1),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,,class VI chitin synthase,,,,unaffected pathogenicity,,no,,,,reduced,,wild type,reduced,no,Congo red; calcofluor white; H2O2; SDS; sorbitol; NaCl,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31461507,PubMed,10.1371/journal.ppat.1007964,PLoS Pathog. 2019 Aug 28;15(8):e1007964,yuxianxia@cqu.edu.cn,"Inactivation of MaChsIII, MaChsV, or MaChsVII impaired appressorium formation, affected growth of in insecta produced hyphal bodies, and altered the surface properties of conidia and hyphal bodies, resulting in defects in the ability of the mutant strains to evade insect immune responses.",J Zhang 2019,2019,7 genes,Zhang-2019-Members of chitin synthase family i,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14723,PHI:9491,UniProt,E9E1W3,GenBank,EFY90060,,,CQMa 102,MaChsIII (XP_007810158.1),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,,chitin synthase III,,,,reduced virulence,,yes,,,,reduced,,reduced; aberrant,increased,no,Congo red; calcofluor white; H2O2; SDS; sorbitol; NaCl,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31461507,PubMed,10.1371/journal.ppat.1007964,PLoS Pathog. 2019 Aug 28;15(8):e1007964,yuxianxia@cqu.edu.cn,"Inactivation of MaChsIII, MaChsV, or MaChsVII impaired appressorium formation, affected growth of in insecta produced hyphal bodies, and altered the surface properties of conidia and hyphal bodies, resulting in defects in the ability of the mutant strains to evade insect immune responses.",J Zhang 2019,2019,7 genes,Zhang-2019-Members of chitin synthase family i,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14724,PHI:9492,UniProt,E9EFJ1,GenBank,EFY85339,,,CQMa 102,MaChsV (XP_007814979.1),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,,class V chitin synthase,,,,reduced virulence,,yes,,,,reduced,,reduced; aberrant,wild type,no,Congo red; calcofluor white; H2O2; SDS; sorbitol; NaCl,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31461507,PubMed,10.1371/journal.ppat.1007964,PLoS Pathog. 2019 Aug 28;15(8):e1007964,yuxianxia@cqu.edu.cn,"Inactivation of MaChsIII, MaChsV, or MaChsVII impaired appressorium formation, affected growth of in insecta produced hyphal bodies, and altered the surface properties of conidia and hyphal bodies, resulting in defects in the ability of the mutant strains to evade insect immune responses.",J Zhang 2019,2019,7 genes,Zhang-2019-Members of chitin synthase family i,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14725,PHI:9493,UniProt,E9EFJ0,GenBank,EFY85338,,,CQMa 102,MaChsVII (XP_007814978.1),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,,class VII chitin synthase,,,,reduced virulence,,yes,,,,reduced,,reduced; aberrant,reduced,no,Congo red; calcofluor white; H2O2; SDS; sorbitol; NaCl,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,31461507,PubMed,10.1371/journal.ppat.1007964,PLoS Pathog. 2019 Aug 28;15(8):e1007964,yuxianxia@cqu.edu.cn,"Inactivation of MaChsIII, MaChsV, or MaChsVII impaired appressorium formation, affected growth of in insecta produced hyphal bodies, and altered the surface properties of conidia and hyphal bodies, resulting in defects in the ability of the mutant strains to evade insect immune responses.",J Zhang 2019,2019,7 genes,Zhang-2019-Members of chitin synthase family i,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14726,PHI:9494,UniProt,G4MWY1,GenBank,EHA54273,,,70-15,MoGT2 (MGG_01191),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,type 2 glycosyltransferase,,,KEGG pathway,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,,no,NaCl; KCl; sorbitol; sodium dodecyl sulfate; Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31484736,PubMed,10.1128/mSphere.00309-19,mSphere. 2019 Sep 4;4(5),dengyz@scau.edu.cn.,"Targeted gene deletion mutants of MoGT2 (mogt2Δ strains) were nonpathogenic and were impaired in vegetative growth, conidiation, and appressorium formation at hyphal tips.",S Deng 2019,2019,1 gene,Deng-2019-MoGT2 Is Essential for Morphogenesis,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14727,PHI:9494,UniProt,G4MWY1,GenBank,EHA54273,,,70-15,MoGT2 (MGG_01191),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,type 2 glycosyltransferase,,,KEGG pathway,loss of pathogenicity,,yes,,,,reduced,,reduced; aberrant,,no,NaCl; KCl; sorbitol; sodium dodecyl sulfate; Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31484736,PubMed,10.1128/mSphere.00309-19,mSphere. 2019 Sep 4;4(5),dengyz@scau.edu.cn.,"Targeted gene deletion mutants of MoGT2 (mogt2Δ strains) were nonpathogenic and were impaired in vegetative growth, conidiation, and appressorium formation at hyphal tips.",S Deng 2019,2019,1 gene,Deng-2019-MoGT2 Is Essential for Morphogenesis,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14728,PHI:9495,,no data found,GenBank,BAH62712,,,NTUH-K2044,frwC (KP1_1992),,,,,,,573,Klebsiella pneumoniae,484021,NTUH-2044,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative fructose-specific phosphotransferase enzyme IIC,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29844239,PubMed,10.1128/IAI.00340-18,Infect Immun. 2018 Jul 23;86(8),libei2381@sina.com,FrwC deletion enhanced biofilm formation and capsular polysaccharide (CPS) biosynthesis but decreased the growth rate and lethality in mice.,D Lin 2018,2018,1 gene,Lin-2018-The Fructose-Specific Phosphotransfer,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14729,PHI:9496,UniProt,A0A0H3NC59,GenBank,CBW17849,,,SL1344,yeaB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,RNA methyltransferase,,,pstSCAB regulatory pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31487966,PubMed,10.3390/ijms20184339,Int J Mol Sci. 2019 Sep 4;20(18),jianglingyan@nankai.edu.cn,Deletion of yaeB significantly impaired S. Typhimurium growth in macrophages and virulence in mice.,H Zhang 2019,2019,1 gene,"Zhang-2019-YaeB, Expressed in Response to the",BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14730,PHI:9496,UniProt,A0A0H3NC59,GenBank,CBW17849,,,SL1344,yeaB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage cell line,RNA methyltransferase,,,pstSCAB regulatory pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31487966,PubMed,10.3390/ijms20184339,Int J Mol Sci. 2019 Sep 4;20(18),jianglingyan@nankai.edu.cn,Deletion of yaeB significantly impaired S. Typhimurium growth in macrophages and virulence in mice.,H Zhang 2019,2019,1 gene,"Zhang-2019-YaeB, Expressed in Response to the",BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14731,PHI:9497,UniProt,A0A2R4HWN2,GenBank,EAA7695473,,,CFSAN043232,sseK1,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain 13076,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),,,,peritoneal macrophage,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29458091,PubMed,10.1016/j.micpath.2018.02.030,Microb Pathog. 2018 Apr;117:270-275,cjzhang@sina.com,"SseK1 deletion mutant resulted in deficient biofilm formation, and then decreased the proliferation of bacteria in macrophages and in vivo.",Y Yang 2018,2018,1 gene,Yang-2018-Role of the sseK1 gene in the pathog,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14732,PHI:9497,UniProt,A0A2R4HWN2,GenBank,EAA7695473,,,CFSAN043232,sseK1,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain 13076,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29458091,PubMed,10.1016/j.micpath.2018.02.030,Microb Pathog. 2018 Apr;117:270-275,cjzhang@sina.com,"SseK1 deletion mutant resulted in deficient biofilm formation, and then decreased the proliferation of bacteria in macrophages and in vivo.",Y Yang 2018,2018,1 gene,Yang-2018-Role of the sseK1 gene in the pathog,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14733,PHI:9497,UniProt,A0A2R4HWN2,GenBank,EAA7695473,,,CFSAN043232,sseK1,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain 13076,gastroenteritis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29458091,PubMed,10.1016/j.micpath.2018.02.030,Microb Pathog. 2018 Apr;117:270-275,cjzhang@sina.com,"SseK1 deletion mutant did not affect the growth, adherence and invasion of Salmonella enteritidis when compared to the wild-type.",Y Yang 2018,2018,1 gene,Yang-2018-Role of the sseK1 gene in the pathog,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14734,PHI:9498,UniProt,K9GFD1,GenBank,EKV11981,,,Pd1,SUT1 (PDIP_54000),,,,,,,36651,Penicillium digitatum,1170230,Pd1,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),,,,exocarp,putative sucrose transporter,,,,reduced virulence,,,,,,,,wild type,,no,imazalil; prochloraz; philabuster; thiabendazol,imazalil: CHEBI:81927; prochloraz: CHEBI:8434; Philabuster cas no.: CAS:494775-01-8; thiabendazole: CHEBI:45979,,,,,gene deletion: full,,,YVS,28754208,PubMed,10.1016/j.micres.2017.06.008,Microbiol Res. 2017 Oct;203:57-67,pasantor@upv.es,"The ΔPdSUT1 mutants generated by gene elimination showed reduction in fungal virulence during citrus fruit infection assayed in mature fruit at 20°C, however, the overexpression mutants did not increased disease severity.",M de Ramon-Carbonell 2017,2017,1 gene,Ramon-Carbonell-2017-Involvement of Penicilliu,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14735,PHI:9498,UniProt,K9GFD1,GenBank,EKV11981,,,Pd1,SUT1 (PDIP_54000),,,,,,,36651,Penicillium digitatum,1170230,Pd1,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),,,,exocarp,putative sucrose transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,imazalil; prochloraz; philabuster; thiabendazol,imazalil: CHEBI:81927; prochloraz: CHEBI:8434; Philabuster cas no.: CAS:494775-01-8; thiabendazole: CHEBI:45979,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28754208,PubMed,10.1016/j.micres.2017.06.008,Microbiol Res. 2017 Oct;203:57-67,pasantor@upv.es,"The ΔPdSUT1 mutants generated by gene elimination showed reduction in fungal virulence during citrus fruit infection assayed in mature fruit at 20°C, however, the overexpression mutants did not increased disease severity.",M de Ramon-Carbonell 2017,2017,1 gene,Ramon-Carbonell-2017-Involvement of Penicilliu,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14736,PHI:9498,UniProt,K9GFD1,GenBank,EKV11981,,,Pd1,SUT1 (PDIP_54000),,,,,,,36651,Penicillium digitatum,,Pd27,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),,,,exocarp,putative sucrose transporter,,,,reduced virulence,,,,,,,,wild type,,no,imazalil; prochloraz; philabuster; thiabendazol,imazalil: CHEBI:81927; prochloraz: CHEBI:8434; Philabuster cas no.: CAS:494775-01-8; thiabendazole: CHEBI:45979,,,,,gene deletion: full,,,YVS,28754208,PubMed,10.1016/j.micres.2017.06.008,Microbiol Res. 2017 Oct;203:57-67,pasantor@upv.es,"The ΔPdSUT1 mutants generated by gene elimination showed reduction in fungal virulence during citrus fruit infection assayed in mature fruit at 20°C, however, the overexpression mutants did not increased disease severity.",M de Ramon-Carbonell 2017,2017,1 gene,Ramon-Carbonell-2017-Involvement of Penicilliu,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14737,PHI:9498,UniProt,K9GFD1,GenBank,EKV11981,,,Pd1,SUT1 (PDIP_54000),,,,,,,36651,Penicillium digitatum,,Pd27,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),,,,exocarp,putative sucrose transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,imazalil; prochloraz; philabuster; thiabendazol,imazalil: CHEBI:81927; prochloraz: CHEBI:8434; Philabuster cas no.: CAS:494775-01-8; thiabendazole: CHEBI:45979,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28754208,PubMed,10.1016/j.micres.2017.06.008,Microbiol Res. 2017 Oct;203:57-67,pasantor@upv.es,"The ΔPdSUT1 mutants generated by gene elimination showed reduction in fungal virulence during citrus fruit infection assayed in mature fruit at 20°C, however, the overexpression mutants did not increased disease severity.",M de Ramon-Carbonell 2017,2017,1 gene,Ramon-Carbonell-2017-Involvement of Penicilliu,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14738,PHI:9498,UniProt,K9GFD1,GenBank,EKV11981,,,Pd1,SUT1 (PDIP_54000),,,,,,,36651,Penicillium digitatum,,Pd149,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),,,,exocarp,putative sucrose transporter,,,,reduced virulence,,,,,,,,wild type,,no,imazalil; prochloraz; philabuster; thiabendazol,imazalil: CHEBI:81927; prochloraz: CHEBI:8434; Philabuster cas no.: CAS:494775-01-8; thiabendazole: CHEBI:45979,,,,,gene deletion: full,,,YVS,28754208,PubMed,10.1016/j.micres.2017.06.008,Microbiol Res. 2017 Oct;203:57-67,pasantor@upv.es,"The ΔPdSUT1 mutants generated by gene elimination showed reduction in fungal virulence during citrus fruit infection assayed in mature fruit at 20°C, however, the overexpression mutants did not increased disease severity.",M de Ramon-Carbonell 2017,2017,1 gene,Ramon-Carbonell-2017-Involvement of Penicilliu,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14739,PHI:9498,UniProt,K9GFD1,GenBank,EKV11981,,,Pd1,SUT1 (PDIP_54000),,,,,,,36651,Penicillium digitatum,,Pd149,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),,,,exocarp,putative sucrose transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,imazalil; prochloraz; philabuster; thiabendazol,imazalil: CHEBI:81927; prochloraz: CHEBI:8434; Philabuster cas no.: CAS:494775-01-8; thiabendazole: CHEBI:45979,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28754208,PubMed,10.1016/j.micres.2017.06.008,Microbiol Res. 2017 Oct;203:57-67,pasantor@upv.es,"The ΔPdSUT1 mutants generated by gene elimination showed reduction in fungal virulence during citrus fruit infection assayed in mature fruit at 20°C, however, the overexpression mutants did not increased disease severity.",M de Ramon-Carbonell 2017,2017,1 gene,Ramon-Carbonell-2017-Involvement of Penicilliu,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14740,PHI:9499,UniProt,C3T127,GenBank,ACI80411,,,493/89,ptsI,,,,,,,562,Escherichia coli,,serotype O2 strain DE17,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,heart; liver; spleen; blood; kidney,phosphoenolpyruvate-protein phosphotransferase,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29111323,PubMed,10.1016/j.micpath.2017.10.048,Microb Pathog. 2017 Dec;113:321-329,zhaoguochen@shvri.ac.cn,The deletion of the ptsI gene changed the morphotype and decreased motility and biofilm formation in APEC.,X Wu 2017,2017,1 gene,Wu-2017-The role of the ptsI gene on AI-2 inte,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14741,PHI:9500,UniProt,Q6FMQ2,GenBank,CAG61453,,,CBS 138,ADA2 (CAGL0K06193g),chromosome K,,,,,,5478,Candida glabrata,284593,CBS 138,candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,spleen; kidney; brain,transcriptional adapter 2,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,sodium dodecyl sulfate; calcofluor white; congo red; dithiothreitol; tunicamycin; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B,sodium dodecyl sulfate: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699; fluconazole: CHEBI:46081; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; anidulafungin: CHEBI:55346; micafungin: CHEBI:600520; amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,29311082,PubMed,10.1128/AAC.01924-17,Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e01924-17,ychen28@ntu.edu.tw,"Surprisingly, ada2 mutants were hypervirulent in a murine model of systemic infection, possibly due to the upregulation of multiple adhesin-like genes, increased agar invasion, and overstimulation of murine tumor necrosis factor alpha production.",S J Yu 2018,2018,1 gene,Yu-2018-Deletion of ADA2 increases antifungal,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14742,PHI:9501,UniProt,Q725C8,GenBank,AAT02833,,,4b F2365,aguB (LMOf2365_0045),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,putrescine carbamoyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31480280,PubMed,10.3390/toxins11090508,Toxins (Basel). 2019 Aug 30;11(9),abdelhamed@cvm.msstate.edu,"Bacterial loads in mouse liver and spleen infected by F2365 was significantly higher than it was for F2365ΔaguB, F2365ΔinlC2, F2365Δeiic, F2365Δtkt, and F2365ΔbglG strains.",H Abdelhamed 2019,2019,5 genes,Abdelhamed-2019-Validation of Predicted Virule,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14743,PHI:9502,,no data found,GenBank,AAT03068,,,4b F2365,inlC2 (LMOf2365_0281),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,internalin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31480280,PubMed,10.3390/toxins11090508,Toxins (Basel). 2019 Aug 30;11(9),abdelhamed@cvm.msstate.edu,"Bacterial loads in mouse liver and spleen infected by F2365 was significantly higher than it was for F2365ΔaguB, F2365ΔinlC2, F2365Δeiic, F2365Δtkt, and F2365ΔbglG strains.",H Abdelhamed 2019,2019,5 genes,Abdelhamed-2019-Validation of Predicted Virule,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14744,PHI:9503,,no data found,GenBank,AAT03443,,,4b F2365,eiic (LMOf2365_0661),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,fructose-like permease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31480280,PubMed,10.3390/toxins11090508,Toxins (Basel). 2019 Aug 30;11(9),abdelhamed@cvm.msstate.edu,"Bacterial loads in mouse liver and spleen infected by F2365 was significantly higher than it was for F2365ΔaguB, F2365ΔinlC2, F2365Δeiic, F2365Δtkt, and F2365ΔbglG strains.",H Abdelhamed 2019,2019,5 genes,Abdelhamed-2019-Validation of Predicted Virule,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14745,PHI:9504,,no data found,GenBank,AAT03831,,,4b F2365,tkt (LMOf2365_1054),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transketolase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31480280,PubMed,10.3390/toxins11090508,Toxins (Basel). 2019 Aug 30;11(9),abdelhamed@cvm.msstate.edu,"Bacterial loads in mouse liver and spleen infected by F2365 was significantly higher than it was for F2365ΔaguB, F2365ΔinlC2, F2365Δeiic, F2365Δtkt, and F2365ΔbglG strains.",H Abdelhamed 2019,2019,5 genes,Abdelhamed-2019-Validation of Predicted Virule,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14746,PHI:9505,,no data found,GenBank,AAT05528,,,4b F2365,bglG (LMOf2365_2763),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transcription antiterminator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31480280,PubMed,10.3390/toxins11090508,Toxins (Basel). 2019 Aug 30;11(9),abdelhamed@cvm.msstate.edu,"Bacterial loads in mouse liver and spleen infected by F2365 was significantly higher than it was for F2365ΔaguB, F2365ΔinlC2, F2365Δeiic, F2365Δtkt, and F2365ΔbglG strains.",H Abdelhamed 2019,2019,5 genes,Abdelhamed-2019-Validation of Predicted Virule,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14747,PHI:9501,UniProt,Q725C8,GenBank,AAT02833,,,4b F2365,aguB (LMOf2365_0045),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,putrescine carbamoyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31480280,PubMed,10.3390/toxins11090508,Toxins (Basel). 2019 Aug 30;11(9),abdelhamed@cvm.msstate.edu,"F2365ΔinlC2, F2365Δeiic and F2365Δtkt exhibited a significant reduction in adhesion to Caco-2 cells compared to parent F2365 strain, the invasion of F2365ΔaguB, F2365ΔinlC2, and F2365ΔbglG decreased significantly compared with the parent strain.",H Abdelhamed 2019,2019,5 genes,Abdelhamed-2019-Validation of Predicted Virule,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14748,PHI:9502,,no data found,GenBank,AAT03068,,,4b F2365,inlC2 (LMOf2365_0281),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31480280,PubMed,10.3390/toxins11090508,Toxins (Basel). 2019 Aug 30;11(9),abdelhamed@cvm.msstate.edu,"F2365ΔinlC2, F2365Δeiic and F2365Δtkt exhibited a significant reduction in adhesion to Caco-2 cells compared to parent F2365 strain, the invasion of F2365ΔaguB, F2365ΔinlC2, and F2365ΔbglG decreased significantly compared with the parent strain.",H Abdelhamed 2019,2019,5 genes,Abdelhamed-2019-Validation of Predicted Virule,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14749,PHI:9503,,no data found,GenBank,AAT03443,,,4b F2365,eiic (LMOf2365_0661),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,fructose-like permease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31480280,PubMed,10.3390/toxins11090508,Toxins (Basel). 2019 Aug 30;11(9),abdelhamed@cvm.msstate.edu,"F2365ΔinlC2, F2365Δeiic and F2365Δtkt exhibited a significant reduction in adhesion to Caco-2 cells compared to parent F2365 strain, the invasion of F2365ΔaguB, F2365ΔinlC2, and F2365ΔbglG decreased significantly compared with the parent strain.",H Abdelhamed 2019,2019,5 genes,Abdelhamed-2019-Validation of Predicted Virule,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14750,PHI:9504,,no data found,GenBank,AAT03831,,,4b F2365,tkt (LMOf2365_1054),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,transketolase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31480280,PubMed,10.3390/toxins11090508,Toxins (Basel). 2019 Aug 30;11(9),abdelhamed@cvm.msstate.edu,"F2365ΔinlC2, F2365Δeiic and F2365Δtkt exhibited a significant reduction in adhesion to Caco-2 cells compared to parent F2365 strain, the invasion of F2365ΔaguB, F2365ΔinlC2, and F2365ΔbglG decreased significantly compared with the parent strain.",H Abdelhamed 2019,2019,5 genes,Abdelhamed-2019-Validation of Predicted Virule,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14751,PHI:9505,,no data found,GenBank,AAT05528,,,4b F2365,bglG (LMOf2365_2763),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,transcription antiterminator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31480280,PubMed,10.3390/toxins11090508,Toxins (Basel). 2019 Aug 30;11(9),abdelhamed@cvm.msstate.edu,"F2365ΔinlC2, F2365Δeiic and F2365Δtkt exhibited a significant reduction in adhesion to Caco-2 cells compared to parent F2365 strain, the invasion of F2365ΔaguB, F2365ΔinlC2, and F2365ΔbglG decreased significantly compared with the parent strain.",H Abdelhamed 2019,2019,5 genes,Abdelhamed-2019-Validation of Predicted Virule,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14752,PHI:9506,,no data found,,,,,,sRNA34,,,,,,,1307,Streptococcus suis,391295,05ZYH33,meningitis; septicemia; endocarditis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,regulatory small non-coding RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31499182,PubMed,10.1016/j.micpath.2019.103730,Microb Pathog. 2019 Sep 6;137:103730,nkuyfq@163.com,"The inactivation of sRNA34 significantly elongated the cellular chain, remarkably increased sensitivity to phagocytosis by RAW264.7, and attenuated virulence in a mouse infection model.",X Gong 2019,2019,1 gene,Gong-2019-A novel small RNA contributes to res,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14753,PHI:9506,,no data found,,,,,,sRNA34,,,,,,,1307,Streptococcus suis,391295,05ZYH33,meningitis; septicemia; endocarditis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,regulatory small non-coding RNA,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31499182,PubMed,10.1016/j.micpath.2019.103730,Microb Pathog. 2019 Sep 6;137:103730,nkuyfq@163.com,There was no significant difference in adhesion to epithelial cells between the mutant strain and the wild type.,X Gong 2019,2019,1 gene,Gong-2019-A novel small RNA contributes to res,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14754,PHI:9506,,no data found,,,,,,sRNA34,,,,,,,1307,Streptococcus suis,391295,05ZYH33,meningitis; septicemia; endocarditis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage cell line,regulatory small non-coding RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31499182,PubMed,10.1016/j.micpath.2019.103730,Microb Pathog. 2019 Sep 6;137:103730,nkuyfq@163.com,"The inactivation of sRNA34 significantly elongated the cellular chain, remarkably increased sensitivity to phagocytosis by RAW264.7, and attenuated virulence in a mouse infection model.",X Gong 2019,2019,1 gene,Gong-2019-A novel small RNA contributes to res,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14755,PHI:9507,UniProt,P43464,GenBank,CAA83535,,,enteroaggregative 17-2,aggR,,,,,,,562,Escherichia coli,216592,EAEC 042,diarrhea,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31456762,PubMed,10.3389/fmicb.2019.01791,Front. Microbiol. 10:1791,liliana.spano@ufes.br,The EAEC 042 aggR mutant strain showed a significant reduction in the mortality of the inoculated larvae compared to the wild-type strain.,C G Guerrieri 2019,2019,1 gene,Guerrieri-2019-Typical and Atypical Enteroaggr,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14756,PHI:9508,UniProt,Q8X6J9,GenBank,AE005205_3,,,EDL933,ovrB (Z0346),,,,,,,562,Escherichia coli,,serotype O157,hemorrhagic colitis; hemolytic uremic syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,intestine,LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31502495,PubMed,10.1080/21505594.2019.1661721,"Virulence, 10:1, 783-792",yangbin@nankai.edu.cn,OvrB promoted O157 colonization in the mouse intestine.,B Yang 2019,2019,1 gene,Liu-2019-LysR-type transcriptional regulator O,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14757,PHI:9508,UniProt,Q8X6J9,GenBank,AE005205_3,,,EDL933,ovrB (Z0346),,,,,,,562,Escherichia coli,,serotype O157,hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31502495,PubMed,10.1080/21505594.2019.1661721,"Virulence, 10:1, 783-792",yangbin@nankai.edu.cn,OvrB was required for bacterial adherence to host cells.,B Yang 2019,2019,1 gene,Liu-2019-LysR-type transcriptional regulator O,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14758,PHI:9508,UniProt,Q8X6J9,GenBank,AE005205_3,,,EDL933,ovrB (Z0346),,,,,,,562,Escherichia coli,,serotype O157,hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31502495,PubMed,10.1080/21505594.2019.1661721,"Virulence, 10:1, 783-792",yangbin@nankai.edu.cn,OvrB was required for bacterial adherence to host cells.,B Yang 2019,2019,1 gene,Liu-2019-LysR-type transcriptional regulator O,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14759,PHI:9509,UniProt,Q83EQ0,GenBank,AAO89823,,,RSA 493,CBU_0265,,,,,,,777,Coxiella burnetii,,RSA 439,Q fever,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glucose/galactose transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31527117,PubMed,10.1042/BCJ20190504,Biochem J. 2019 Oct 15;476(19):2851-2867,hnewton@unimelb.edu.au,Loss of CBU0265 and CBU0347 had no impact on intracellular replication or virulence.,H J Newton 2019,2019,2 genes,Kuba-2019-Coxiella burnetii utilizes both glut,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14760,PHI:9509,UniProt,Q83EQ0,GenBank,AAO89823,,,RSA 493,CBU_0265,,,,,,,777,Coxiella burnetii,,RSA 439,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,glucose/galactose transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31527117,PubMed,10.1042/BCJ20190504,Biochem J. 2019 Oct 15;476(19):2851-2867,hnewton@unimelb.edu.au,Loss of CBU0265 and CBU0347 had no impact on intracellular replication or virulence.,H J Newton 2019,2019,2 genes,Kuba-2019-Coxiella burnetii utilizes both glut,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14761,PHI:9509,UniProt,Q83EQ0,GenBank,AAO89823,,,RSA 493,CBU_0265,,,,,,,777,Coxiella burnetii,,RSA 439,Q fever,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,glucose/galactose transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31527117,PubMed,10.1042/BCJ20190504,Biochem J. 2019 Oct 15;476(19):2851-2867,hnewton@unimelb.edu.au,Loss of CBU0265 and CBU0347 had no impact on intracellular replication or virulence.,H J Newton 2019,2019,2 genes,Kuba-2019-Coxiella burnetii utilizes both glut,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14762,PHI:9510,UniProt,Q83EH4,GenBank,AAO89902,,,RSA 493,CBU_0347,,,,,,,777,Coxiella burnetii,,RSA 439,Q fever,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,D-xylose-proton symporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31527117,PubMed,10.1042/BCJ20190504,Biochem J. 2019 Oct 15;476(19):2851-2867,hnewton@unimelb.edu.au,Loss of CBU0265 and CBU0347 had no impact on intracellular replication or virulence.,H J Newton 2019,2019,2 genes,Kuba-2019-Coxiella burnetii utilizes both glut,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14763,PHI:9511,,no data found,GenBank,NJ56_RS12465,,,,tcpA,,,,,,,29486,Yersinia ruckeri,,SC09,enteric redmouth disease,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,liver; kidney; spleen; head kidney,TIR-containing virulent protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31470137,PubMed,10.1016/j.fsi.2019.08.069,Fish Shellfish Immunol.2019 Nov;94 (2019):58–65,kywang1955@126.com,"The tcpA deletion mutant from the Yersinia ruckeri SC09 affected intracellular survival, but not adherence and invasion capacities in primary rainbow trout head kidney macrophages.",T Liu 2019,2019,1 gene,"Liu-2019-TcpA, a novel Yersinia ruckeri TIR-co",BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14764,PHI:9512,,no data found,,,,,,ZtVf1,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Obelisk,,,leaf,transcription factor,,,,reduced virulence,,,yes,yes,,reduced,,reduced,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29031630,PubMed,10.1016/j.fgb.2017.10.003,Fungal Genet Biol. 2017 Dec;109:26-35,r.mehrabi@areeo.ac.ir,ZtVf1 deletion affected hyphal branching and biomass production.,N Mohammadi 2017,2017,1 gene,Mohammadi-2017-The ZtVf1 transcription factor_1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14765,PHI:9513,UniProt,A0A125YA45,GenBank,ACO25785,,,03BB102,pagA2,,,,,,,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen,protective antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"PagA2 minimally contributed to virulence of B. cereus G9241, whereas, PagA1 was essential for virulence of B. cereus G9241 during s.c. and i.n challenge of mice.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14766,PHI:9513,UniProt,A0A125YA45,GenBank,ACO25785,,,03BB102,pagA2,,,,,,,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,protective antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"PagA2 minimally contributed to virulence of B. cereus G9241, whereas, PagA1 was essential for virulence of B. cereus G9241 during s.c. and i.n challenge of mice.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14767,PHI:9514,UniProt,A0A125YA28,GenBank,ACO25768,,,03BB102,pagA1,,,,,,,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen,protective antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"PagA2 minimally contributed to virulence of B. cereus G9241, whereas, PagA1 was essential for virulence of B. cereus G9241 during s.c. and i.n challenge of mice.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14768,PHI:9514,UniProt,A0A125YA28,GenBank,ACO25768,,,03BB102,pagA1,,,,,,,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,protective antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"PagA2 minimally contributed to virulence of B. cereus G9241, whereas, PagA1 was essential for virulence of B. cereus G9241 during s.c. and i.n challenge of mice.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14769,PHI:9514,UniProt,A0A125YA28,GenBank,ACO25768,,,03BB102,pagA1,,,,,,PHI:9513,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen,protective antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"PagA2 minimally contributed to virulence of B. cereus G9241, whereas, PagA1 was essential for virulence of B. cereus G9241 during s.c. and i.n challenge of mice.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14770,PHI:9513,UniProt,A0A125YA45,GenBank,ACO25785,,,03BB102,pagA2,,,,,,PHI:9514,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,protective antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"PagA2 minimally contributed to virulence of B. cereus G9241, whereas, PagA1 was essential for virulence of B. cereus G9241 during s.c. and i.n challenge of mice.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14771,PHI:9514,UniProt,A0A125YA62,GenBank,ACO25768,,,03BB102,pagA1,,,,,,PHI:9513,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen,protective antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"PagA2 minimally contributed to virulence of B. cereus G9241, whereas, PagA1 was essential for virulence of B. cereus G9241 during s.c. and i.n challenge of mice.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14772,PHI:9513,UniProt,A0A125YA79,GenBank,ACO25785,,,03BB102,pagA2,,,,,,PHI:9514,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,protective antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"PagA2 minimally contributed to virulence of B. cereus G9241, whereas, PagA1 was essential for virulence of B. cereus G9241 during s.c. and i.n challenge of mice.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14773,PHI:9515,UniProt,Q4MV79,GenBank,EAL15945,,,G9241,cer,,,,,,,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen,putative ADP-ribosyltransferase certhrax,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"While lethal factor contributed to virulence in B. cereus G9241, Certhrax attenuated virulence of the pathogen.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14774,PHI:9515,UniProt,Q4MV79,GenBank,EAL15945,,,G9241,cer,,,,,,,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,putative ADP-ribosyltransferase certhrax,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"While lethal factor contributed to virulence in B. cereus G9241, Certhrax attenuated virulence of the pathogen.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14775,PHI:9516,UniProt,A0A125YA09,GenBank,ACO25749,,,03BB102,lef,,,,,,,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen,anthrax lethal factor endopeptidase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"While lethal factor contributed to virulence in B. cereus G9241, Certhrax attenuated virulence of the pathogen.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14776,PHI:9516,UniProt,A0A125YA09,GenBank,ACO25749,,,03BB102,lef,,,,,,,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,anthrax lethal factor endopeptidase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"While lethal factor contributed to virulence in B. cereus G9241, Certhrax attenuated virulence of the pathogen.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14777,PHI:9515,UniProt,Q4MV79,GenBank,EAL15945,,,G9241,cer,,,,,,PHI:9516,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen,putative ADP-ribosyltransferase certhrax,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"While lethal factor contributed to virulence in B. cereus G9241, Certhrax attenuated virulence of the pathogen.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14778,PHI:9516,UniProt,A0A125YA09,GenBank,ACO25749,,,03BB102,lef,,,,,,PHI:9515,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,anthrax lethal factor endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"While lethal factor contributed to virulence in B. cereus G9241, Certhrax attenuated virulence of the pathogen.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14779,PHI:9515,UniProt,Q4MV79,GenBank,EAL15945,,,G9241,cer,,,,,,PHI:9516,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen,putative ADP-ribosyltransferase certhrax,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"While lethal factor contributed to virulence in B. cereus G9241, Certhrax attenuated virulence of the pathogen.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14780,PHI:9516,UniProt,A0A125YA09,GenBank,ACO25749,,,03BB102,lef,,,,,,PHI:9515,1396,Bacillus cereus,269801,G9241,anthrax-like lung infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,anthrax lethal factor endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29610258,PubMed,10.1128/IAI.00207-18,Infect Immun. 2018 May 22;86(6),alison.obrien@usuhs.edu,"While lethal factor contributed to virulence in B. cereus G9241, Certhrax attenuated virulence of the pathogen.",Y I Seldina 2018,2018,4 genes,Seldina-2018-Certhrax is an Anti-Virulence Fac,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14781,PHI:9517,UniProt,I1S8D3,GenBank,CEF85795,,,PH-1,FgEch1 (FGSG_13111),chromosome 4,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,,enoyl-CoA hydratase,,,,reduced virulence,,,,,,reduced,wild type,reduced,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31463774,PubMed,10.1007/s00294-019-01028-z,Curr Genet. 2019 Aug 28,liangyc@sdau.edu.cn,Deletion of FgEch1 led to increased production of lipid droplets and autophagy.,L Tang 2019,2019,1 gene,Tang-2019-Mitochondrial FgEch1 is responsible,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14782,PHI:9518,UniProt,A0A0H2XIZ5,GenBank,ABD21986,,,USA300_FPR3757,SAUSA300_1968,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,soft tissue lesion; pneumonia; toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),,,,peritoneal macrophage,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31445123,PubMed,10.1016/j.micpath.2019.103690,Microb Pathog. 2019;136:103690,zhengf82@gmail.com,Inactivation of SAUSA300_1968 enhanced S. aureus survival in mouse macrophages.,Y Yue 2019,2019,1 gene,Yue-2019-Influence of transcription regulator,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14783,PHI:9519,UniProt,A7EXS0,GenBank,EDN94262,,,1980,SsFdh1 (SS1G_10135),,,,Ssnsd1,UniProt: no data found; GenBank: no data found,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,formaldehyde dehydrogenase,,,,reduced virulence,,yes,,yes,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,gene deletion: full; gene complementation,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,"SsFdh1 functions in formaldehyde detoxification, nitrogen metabolism, sclerotium development, and pathogenicity.",G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14784,PHI:9519,UniProt,A7EXS0,GenBank,EDN94262,,,1980,SsFdh1 (SS1G_10135),,,,Ssnsd1,UniProt: no data found; GenBank: no data found,PHI:9520,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,formaldehyde dehydrogenase,,,,reduced virulence,,no,,no,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,Overexpressing Ssfdh1 in the ΔSsnsd1 background allowed host penetration but symptom development was delayed.,G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14785,PHI:9520,UniProt,A0A1D9QMN1,GenBank,sscle_16g109570,,,,Ssnsd1,,,,SsFdh1,UniProt: A7EXS0; GenBank: EDN94262,PHI:9519,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,GATA transcription factor,,,,reduced virulence,,no,,no,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,gene deletion: full; gene complementation,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,Overexpressing Ssfdh1 in the ΔSsnsd1 background allowed host penetration but symptom development was delayed.,G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14786,PHI:9520,UniProt,A0A1D9QMN1,GenBank,sscle_16g109570,,,,Ssnsd1,,,,SsFdh1,UniProt: A7EXS0; GenBank: EDN94262,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,GATA transcription factor,,,,reduced virulence,,yes,,yes,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,gene deletion: full; gene complementation,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,Both ΔSsfdh1 mutant and the ΔSsnsd1mutant was nonpathogenic on unwounded host tissue.,G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14787,PHI:9520,UniProt,A0A1D9QMN1,GenBank,sscle_16g109570,,,,Ssnsd1,,,,SsFdh1,UniProt: A7EXS0; GenBank: EDN94262,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,GATA transcription factor,,,,reduced virulence,,yes,,yes,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,gene deletion: full; gene complementation,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,Both ΔSsfdh1 mutant and the ΔSsnsd1mutant was nonpathogenic on unwounded host tissue.,G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14788,PHI:9519,UniProt,A7EXS0,GenBank,EDN94262,,,1980,SsFdh1 (SS1G_10135),,,,Ssnsd1,UniProt: no data found; GenBank: no data found,PHI:9520,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,formaldehyde dehydrogenase,,,,reduced virulence,,no,,no,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,Overexpressing Ssfdh1 in the ΔSsnsd1 background allowed host penetration but symptom development was delayed.,G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14789,PHI:9520,UniProt,A0A1D9QMN1,GenBank,sscle_16g109570,,,,Ssnsd1,,,,SsFdh1,UniProt: A7EXS0; GenBank: EDN94262,PHI:9519,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,GATA transcription factor,,,,reduced virulence,,no,,no,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,gene deletion: full; gene complementation,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,Overexpressing Ssfdh1 in the ΔSsnsd1 background allowed host penetration but symptom development was delayed.,G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14790,PHI:9519,UniProt,A7EXS0,GenBank,EDN94262,,,1980,SsFdh1 (SS1G_10135),,C44/C173,,Ssnsd1,UniProt: no data found; GenBank: no data found,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,formaldehyde dehydrogenase,,,,reduced virulence,,yes,,yes,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,gene mutation,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,"SsFdh1 functions in formaldehyde detoxification, nitrogen metabolism, sclerotium development, and pathogenicity.",G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14791,PHI:9520,UniProt,A0A1D9QMN1,GenBank,sscle_16g109570,,,,Ssnsd1,,C331/C334,,SsFdh1,UniProt: A7EXS0; GenBank: EDN94262,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,GATA transcription factor,,,,reduced virulence,,yes,,yes,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,gene mutation,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,Both ΔSsfdh1 mutant and the ΔSsnsd1mutant was nonpathogenic on unwounded host tissue.,G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14792,PHI:9519,UniProt,A7EXS0,GenBank,EDN94262,,,1980,SsFdh1 (SS1G_10135),,C44/C173,,Ssnsd1,UniProt: no data found; GenBank: no data found,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,formaldehyde dehydrogenase,,,,reduced virulence,,yes,,yes,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,gene mutation,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,"SsFdh1 functions in formaldehyde detoxification, nitrogen metabolism, sclerotium development, and pathogenicity.",G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14793,PHI:9520,UniProt,A0A1D9QMN1,GenBank,sscle_16g109570,,,,Ssnsd1,,C331/C334,,SsFdh1,UniProt: A7EXS0; GenBank: EDN94262,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,GATA transcription factor,,,,reduced virulence,,yes,,yes,,,reduced,reduced,,no,KCl; NaCl; sorbitol; H2O2; formaldehyde,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; formaldehyde: CHEBI:16842,,,,,gene mutation,,,YVS,31506263,PubMed,10.1128/mSystems.00397-19,mSystems. 2019 Sep 10;4(5),panhongyu@jlu.edu.cn,Both ΔSsfdh1 mutant and the ΔSsnsd1mutant was nonpathogenic on unwounded host tissue.,G Zhu 2019,2019,2 genes,Zhu-2019-The Formaldehyde Dehydrogenase SsFdh1,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14794,PHI:9521,UniProt,A0A0H3NC74,GenBank,CBW17864,,,SL1344,yobH (SL1344_1770),,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,invasion factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31484980,PubMed,10.1038/s41598-019-49192-z,Sci Rep. 2019 Sep 4;9(1):12725,victor@ibt.unam.mx,The ΔyobH mutant showed a ∼3-fold decrease in the invasion of both HeLa cells and RAW264.7 macrophages with respect to the WT.,M M Banda 2019,2019,3 genes,Banda-2019-HilD induces expression of a novel,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14795,PHI:9521,UniProt,A0A0H3NC74,GenBank,CBW17864,,,SL1344,yobH (SL1344_1770),,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,invasion factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31484980,PubMed,10.1038/s41598-019-49192-z,Sci Rep. 2019 Sep 4;9(1):12725,victor@ibt.unam.mx,The ΔyobH mutant showed a ∼3-fold decrease in the invasion of both HeLa cells and RAW264.7 macrophages with respect to the WT.,M M Banda 2019,2019,3 genes,Banda-2019-HilD induces expression of a novel,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14796,PHI:9522,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,AraC-like transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31484980,PubMed,10.1038/s41598-019-49192-z,Sci Rep. 2019 Sep 4;9(1):12725,victor@ibt.unam.mx,The ΔhilD mutant was unable to invade the HeLa cells and RAW264.7 macrophages.,M M Banda 2019,2019,3 genes,Banda-2019-HilD induces expression of a novel,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14797,PHI:9522,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,AraC-like transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31484980,PubMed,10.1038/s41598-019-49192-z,Sci Rep. 2019 Sep 4;9(1):12725,victor@ibt.unam.mx,The ΔhilD mutant was unable to invade the HeLa cells and RAW264.7 macrophages.,M M Banda 2019,2019,3 genes,Banda-2019-HilD induces expression of a novel,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14798,PHI:9523,UniProt,A0A0H3NKV1,GenBank,CBW17421,,,SL1344,ssrB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31484980,PubMed,10.1038/s41598-019-49192-z,Sci Rep. 2019 Sep 4;9(1):12725,victor@ibt.unam.mx,The ΔssrB mutant invaded these cells at similar levels to those showed by the WT.,M M Banda 2019,2019,3 genes,Banda-2019-HilD induces expression of a novel,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14799,PHI:9523,UniProt,A0A0H3NKV1,GenBank,CBW17421,,,SL1344,ssrB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31484980,PubMed,10.1038/s41598-019-49192-z,Sci Rep. 2019 Sep 4;9(1):12725,victor@ibt.unam.mx,The ΔssrB mutant invaded these cells at similar levels to those showed by the WT.,M M Banda 2019,2019,3 genes,Banda-2019-HilD induces expression of a novel,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14800,PHI:9524,UniProt,A0A1D8PP43,GenBank,AOW29909,,,SC5314,ADH1,chromosome 5,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney; liver,alcohol dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31471070,PubMed,10.1016/j.ijmm.2019.151330,Int J Med Microbiol. 2019 Sep;309(6):151330,tzhangh@jnu.edu.cn,ADH1 deletion reduced the adhesion and filamentation ability of C. albicans.,Y Song 2019,2019,1 gene,Song-2019-ADH1 promotes Candida albicans patho,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14801,PHI:9524,UniProt,A0A1D8PP43,GenBank,AOW29909,,,SC5314,ADH1,chromosome 5,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,alcohol dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31471070,PubMed,10.1016/j.ijmm.2019.151330,Int J Med Microbiol. 2019 Sep;309(6):151330,tzhangh@jnu.edu.cn,ADH1 deletion reduced the adhesion and filamentation ability of C. albicans.,Y Song 2019,2019,1 gene,Song-2019-ADH1 promotes Candida albicans patho,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14802,PHI:9524,UniProt,A0A1D8PP43,GenBank,AOW29909,,,SC5314,ADH1,chromosome 5,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,alcohol dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31471070,PubMed,10.1016/j.ijmm.2019.151330,Int J Med Microbiol. 2019 Sep;309(6):151330,tzhangh@jnu.edu.cn,ADH1 deletion reduced the adhesion and filamentation ability of C. albicans.,Y Song 2019,2019,1 gene,Song-2019-ADH1 promotes Candida albicans patho,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14803,PHI:9525,UniProt,A0A384K208,GenBank,ATZ56870,,,B05.10,Bcpg1,BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Wassilewskija,,,leaf,endopolygalacturonase 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31501325,PubMed,10.1073/pnas.1900317116,Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19743-19752,samantha.vernhettes@inra.fr,B. cinerea infection assays showed low virulence for Bcpg1 mutant and a comparable or a higher virulence (on older leaves) for Bcpme1/2 mutants relative to the WT.,A Voxeur 2019,2019,3 genes,Voxeur-2019-Oligogalacturonide production upon,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14804,PHI:9526,UniProt,A0A384JQ57,GenBank,ATZ52640,,,B05.10,Bcpme1,BCIN08,,,,,PHI:9527,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Wassilewskija,,,leaf,pectin esterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31501325,PubMed,10.1073/pnas.1900317116,Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19743-19752,samantha.vernhettes@inra.fr,B. cinerea infection assays showed low virulence for Bcpg1 mutant and a comparable or a higher virulence (on older leaves) for Bcpme1/2 mutants relative to the WT.,A Voxeur 2019,2019,3 genes,Voxeur-2019-Oligogalacturonide production upon,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14805,PHI:9527,UniProt,A0A384JCI5,GenBank,ATZ48137,,,B05.10,Bcpme2,BCIN03,,,,,PHI:9526,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Wassilewskija,,,leaf,pectin esterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31501325,PubMed,10.1073/pnas.1900317116,Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19743-19752,samantha.vernhettes@inra.fr,B. cinerea infection assays showed low virulence for Bcpg1 mutant and a comparable or a higher virulence (on older leaves) for Bcpme1/2 mutants relative to the WT.,A Voxeur 2019,2019,3 genes,Voxeur-2019-Oligogalacturonide production upon,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14806,PHI:9528,UniProt,Q9L8R8,GenBank,AF196486_1,,,240B1,aiiA,,,,,,,644,Aeromonas hydrophila,,YJ-1,diarrhea; nausea; vomiting,bony fishes,90988,Pimephales promelas (related: fathead minnow),EPC cell line,,,skin,N-acyl homoserine lactonase,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31461929,PubMed,10.3390/md17090499,Mar Drugs. 2019 Aug 27;17(9). pii: E499,chuweihua@cpu.edu.cn,AiiAQSI-1 protein exhibited inhibitory activity in both adherence and internalization of A. hydrophila YJ-1 to Epithelioma Papulosum Cyprini (EPC) cells.,B Zhang 2019,2019,1 gene,Zhang-2019-Recombinant N-acyl homoserine lacto,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14807,PHI:9528,UniProt,Q9L8R8,GenBank,AF196486_1,,,240B1,aiiA,,,,,,,644,Aeromonas hydrophila,,YJ-1,diarrhea; nausea; vomiting,bony fishes,217509,Carassius carassius (related: crucian carp),,,,liver; spleen; kidney,N-acyl homoserine lactonase,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31461929,PubMed,10.3390/md17090499,Mar Drugs. 2019 Aug 27;17(9). pii: E499,chuweihua@cpu.edu.cn,AiiAQSI-1 was not toxic for Crucian Carp.,B Zhang 2019,2019,1 gene,Zhang-2019-Recombinant N-acyl homoserine lacto,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14808,PHI:9529,UniProt,O87753,GenBank,ADG27466,,,KP187/08,ompk35,,,,,,,573,Klebsiella pneumoniae,,,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; blood,porin,,,,reduced virulence,,,,,,,,,,no,carbapenem,carbapenem: CHEBI:46765,,,,,gene mutation,,,YVS,31477712,PubMed,10.1038/s41467-019-11756-y,Nat Commun. 2019 Sep 2;10(1):3957,g.frankel@imperial.ac.uk,Loss of both porins in OmpK35ST258/ ΔOmpK36 caused significant attenuation and this strain failed to reach a high pulmonary burden associated with a low level of bacteraemia.,J L C Wong 2019,2019,2 genes,Wong-2019-OmpK36-mediated Carbapenem resistanc,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14809,PHI:9530,UniProt,J9QY50,GenBank,AFR33748,,,HS092187,ompk36,,,,,,,573,Klebsiella pneumoniae,,,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; blood,porin,,,,reduced virulence,,,,,,,,,,no,carbapenem,carbapenem: CHEBI:46765,,,,,gene mutation,,,YVS,31477712,PubMed,10.1038/s41467-019-11756-y,Nat Commun. 2019 Sep 2;10(1):3957,g.frankel@imperial.ac.uk,Loss of both porins in OmpK35ST258/ ΔOmpK36 caused significant attenuation and this strain failed to reach a high pulmonary burden associated with a low level of bacteraemia.,J L C Wong 2019,2019,2 genes,Wong-2019-OmpK36-mediated Carbapenem resistanc,BATCH_096B,2019-10-01,MC,,,,,,,,,,,,,
,,Record 14810,PHI:9531,UniProt,E9EVY3,GenBank,EFZ00405,,,ARSEF 23,mepC (MAA_04182),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ammonium permease,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14811,PHI:9532,UniProt,E9EYA3,GenBank,EFZ00074,,,ARSEF 23,mep2 (MAA_05002),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ammonium permease,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14812,PHI:9533,UniProt,E9F5A9,GenBank,EFY97162,,,ARSEF 23,urease (MAA_07458),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,urease,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14813,PHI:9534,UniProt,E9F076,GenBank,EFY98536,,,ARSEF 23,pr1A (MAA_05675),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,alkaline serine protease,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14814,PHI:9535,UniProt,E9F9L0,GenBank,EFY95503,,,ARSEF 23,hypo (MAA_08959),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,unaffected pathogenicity,,,,,,wild type,,aberrant,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14815,PHI:9536,UniProt,E9FDE9,GenBank,EFY94230,,,ARSEF 23,hyd3 (MAA_10298),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hydrophobin,,,,unaffected pathogenicity,,,,,,reduced,,wild type,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14816,PHI:9531,UniProt,E9EVY3,GenBank,EFZ00405,,,ARSEF 23,mepC (MAA_04182),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,ammonium permease,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14817,PHI:9532,UniProt,E9EYA3,GenBank,EFZ00074,,,ARSEF 23,mep2 (MAA_05002),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,ammonium permease,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14818,PHI:9533,UniProt,E9F5A9,GenBank,EFY97162,,,ARSEF 23,urease (MAA_07458),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,urease,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14819,PHI:9534,UniProt,E9F076,GenBank,EFY98536,,,ARSEF 23,pr1A (MAA_05675),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,alkaline serine protease,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14820,PHI:9535,UniProt,E9F9L0,GenBank,EFY95503,,,ARSEF 23,hypo (MAA_08959),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,hypothetical protein,,,,unaffected pathogenicity,,,,,,wild type,,aberrant,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14821,PHI:9536,UniProt,E9FDE9,GenBank,EFY94230,,,ARSEF 23,hyd3 (MAA_10298),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,hydrophobin,,,,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14822,PHI:9531,UniProt,E9EVY3,GenBank,EFZ00405,,,ARSEF 23,mepC (MAA_04182),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,monocots,4513,Hordeum vulgare (related: Barley),cv. Sprout Master,,,leaf,ammonium permease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14823,PHI:9532,UniProt,E9EYA3,GenBank,EFZ00074,,,ARSEF 23,mep2 (MAA_05002),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,monocots,4513,Hordeum vulgare (related: Barley),cv. Sprout Master,,,leaf,ammonium permease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14824,PHI:9533,UniProt,E9F5A9,GenBank,EFY97162,,,ARSEF 23,urease (MAA_07458),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,monocots,4513,Hordeum vulgare (related: Barley),cv. Sprout Master,,,leaf,urease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14825,PHI:9534,UniProt,E9F076,GenBank,EFY98536,,,ARSEF 23,pr1A (MAA_05675),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,monocots,4513,Hordeum vulgare (related: Barley),cv. Sprout Master,,,leaf,alkaline serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14826,PHI:9535,UniProt,E9F9L0,GenBank,EFY95503,,,ARSEF 23,hypo (MAA_08959),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,monocots,4513,Hordeum vulgare (related: Barley),cv. Sprout Master,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14827,PHI:9536,UniProt,E9FDE9,GenBank,EFY94230,,,ARSEF 23,hyd3 (MAA_10298),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,monocots,4513,Hordeum vulgare (related: Barley),cv. Sprout Master,,,leaf,hydrophobin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31618269,PubMed,10.1371/journal.pone.0223718,PLoS One. 2019 Oct 16;14(10):e0223718,mbidochka@brocku.ca,The enhanced rhizoplane colonization of ?Mep2 and ?MepC and insect derived nitrogen transfer to plant hosts suggested the role of MepC and Mep2 in Metarhizium-plant symbiosis.,S Moonjely 2019,2019,6 genes,Moonjely-2019-Metarhizium robertsii ammonium p,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14828,PHI:9537,UniProt,A0A0B5JGW8,GenBank,AJG01371,,,,cyp-33C9,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,3350,Pinus thunbergii (related: Japanese black pine),,,,seedling,cytochrome P450 family protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31547281,PubMed,10.3390/ijms20184520,Int J Mol Sci. 2019 Sep 12;20(18),gxzhou@issas.ac.cn,Silencing of the cyp-33C9 gene decreased the percentage wilting of P.thunbergii seedlings and reduced the pathogenicity of B.xylophilus.,X Qiu 2019,2019,1 gene,Qiu-2019-Silencing of cyp-33C9 Gene Affects th,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14829,PHI:9538,UniProt,I1S746,GenBank,CEF88366,,,PH-1,acd2 (FGSG_12669),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Apogee,,,spikelet,ACC deaminases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31552072,PubMed,10.3389/fpls.2019.01072,Front Plant Sci. 2019 Sep 10;10:1072,thomas.svoboda@boku.ac.at,"No statistically significant effect of the gene disruptions on fungal spread or mycotoxin content was detected, indicating that the ability of the fungus to manipulate the production of the gaseous plant hormones ethylene and H2S is dispensable for full virulence.",T Svoboda 2019,2019,2 genes,Svoboda-2019-Biochemical Characterization of t,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14830,PHI:9539,UniProt,I1RG29,GenBank,CEF75013,,,PH-1,dcs1 (FGSG_02678),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Apogee,,,spikelet,D-cysteine desulfhydrase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31552072,PubMed,10.3389/fpls.2019.01072,Front Plant Sci. 2019 Sep 10;10:1072,thomas.svoboda@boku.ac.at,"No statistically significant effect of the gene disruptions on fungal spread or mycotoxin content was detected, indicating that the ability of the fungus to manipulate the production of the gaseous plant hormones ethylene and H2S is dispensable for full virulence.",T Svoboda 2019,2019,2 genes,Svoboda-2019-Biochemical Characterization of t,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14831,PHI:9538,UniProt,I1S746,GenBank,CEF88366,,,PH-1,acd2 (FGSG_12669),chromosome 3,,,,,PHI:9539,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Apogee,,,spikelet,ACC deaminases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31552072,PubMed,10.3389/fpls.2019.01072,Front Plant Sci. 2019 Sep 10;10:1072,thomas.svoboda@boku.ac.at,"No statistically significant effect of the gene disruptions on fungal spread or mycotoxin content was detected, indicating that the ability of the fungus to manipulate the production of the gaseous plant hormones ethylene and H2S is dispensable for full virulence.",T Svoboda 2019,2019,2 genes,Svoboda-2019-Biochemical Characterization of t,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14832,PHI:9539,UniProt,I1RG29,GenBank,CEF75013,,,PH-1,dcs1 (FGSG_02678),chromosome 1,,,,,PHI:9538,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Apogee,,,spikelet,D-cysteine desulfhydrase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31552072,PubMed,10.3389/fpls.2019.01072,Front Plant Sci. 2019 Sep 10;10:1072,thomas.svoboda@boku.ac.at,"No statistically significant effect of the gene disruptions on fungal spread or mycotoxin content was detected, indicating that the ability of the fungus to manipulate the production of the gaseous plant hormones ethylene and H2S is dispensable for full virulence.",T Svoboda 2019,2019,2 genes,Svoboda-2019-Biochemical Characterization of t,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14833,PHI:9540,UniProt,Q4WXH8,GenBank,EAL92625,,,Af293,cysB,chromosome 3,,,,,PHI:9541,746128,Aspergillus fumigatus,,ATCC 46645,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cysteine synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31649650,PubMed,10.3389/fmicb.2019.02311,Front Microbiol. 2019 Oct 9;10:2311,jorge.amichelias@manchester.ac.uk,P. aeruginosa could cross-feed A. fumigatus when grown on murine lung tissue and on human bronchial epithelial cells.,J Scott 2019,2019,2 genes,Scott-2019-Pseudomonas aeruginosa-Derived Vola,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14834,PHI:9541,UniProt,Q4WEU7,GenBank,EAL85880,,,Af293,cysD,chromosome 5,,,,,PHI:9540,746128,Aspergillus fumigatus,,ATCC 46645,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,homocysteine synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31649650,PubMed,10.3389/fmicb.2019.02311,Front Microbiol. 2019 Oct 9;10:2311,jorge.amichelias@manchester.ac.uk,P. aeruginosa could cross-feed A. fumigatus when grown on murine lung tissue and on human bronchial epithelial cells.,J Scott 2019,2019,2 genes,Scott-2019-Pseudomonas aeruginosa-Derived Vola,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14835,PHI:9542,UniProt,A0A1D8PRZ8,GenBank,AOW30911,,,SC5314,PTC2,chromosome R,,,,,,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,protein phosphatase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,methyl methanesulfonate (MMS); H2O2; hydroxyurea; cisplatin,H2O2: CHEBI:16240; methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899,,,,,gene mutation,,,YVS,31644792,PubMed,10.1093/femsyr/foz075,FEMS Yeast Res. 2019 Oct 23. pii: foz075,jinrong532@163.com,"Deletion of PTC2 alone resulted in no significant change in cell virulence, but double deletion of PTC2 PPH3 significantly decreased virulence, while double deletions of either PTC2 PSY2 or PTC2 PSY4 caused increased in virulence.",J Feng 2019,2019,4 genes,Feng-2019-Genetic interaction between Ptc2 and,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14836,PHI:9542,UniProt,A0A1D8PRZ8,GenBank,AOW30911,,,SC5314,PTC2,chromosome R,,,,,PHI:9543,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,protein phosphatase,,,,reduced virulence,,,,,,,,increased,,no,methyl methanesulfonate (MMS); H2O2; hydroxyurea; cisplatin,H2O2: CHEBI:16240; methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899,,,,,gene mutation,,,YVS,31644792,PubMed,10.1093/femsyr/foz075,FEMS Yeast Res. 2019 Oct 23. pii: foz075,jinrong532@163.com,"Deletion of PTC2 alone resulted in no significant change in cell virulence, but double deletion of PTC2 PPH3 significantly decreased virulence, while double deletions of either PTC2 PSY2 or PTC2 PSY4 caused increased in virulence.",J Feng 2019,2019,4 genes,Feng-2019-Genetic interaction between Ptc2 and,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14837,PHI:9543,UniProt,A0A1D8PSJ8,GenBank,AOW31118,,,SC5314,PPH3,chromosome R,,,,,PHI:9542,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphoprotein phosphatase PP4 catalytic subunit,,,,reduced virulence,,,,,,,,increased,,no,methyl methanesulfonate (MMS); H2O2; hydroxyurea; cisplatin,H2O2: CHEBI:16240; methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899,,,,,gene mutation,,,YVS,31644792,PubMed,10.1093/femsyr/foz075,FEMS Yeast Res. 2019 Oct 23. pii: foz075,jinrong532@163.com,"Deletion of PTC2 alone resulted in no significant change in cell virulence, but double deletion of PTC2 PPH3 significantly decreased virulence, while double deletions of either PTC2 PSY2 or PTC2 PSY4 caused increased in virulence.",J Feng 2019,2019,4 genes,Feng-2019-Genetic interaction between Ptc2 and,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14838,PHI:9542,UniProt,A0A1D8PRZ8,GenBank,AOW30911,,,SC5314,PTC2,chromosome R,,,,,PHI:9544,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,protein phosphatase,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,methyl methanesulfonate (MMS); H2O2; hydroxyurea; cisplatin,H2O2: CHEBI:16240; methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899,,,,,gene mutation,,,YVS,31644792,PubMed,10.1093/femsyr/foz075,FEMS Yeast Res. 2019 Oct 23. pii: foz075,jinrong532@163.com,"Deletion of PTC2 alone resulted in no significant change in cell virulence, but double deletion of PTC2 PPH3 significantly decreased virulence, while double deletions of either PTC2 PSY2 or PTC2 PSY4 caused increased in virulence.",J Feng 2019,2019,4 genes,Feng-2019-Genetic interaction between Ptc2 and,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14839,PHI:9544,UniProt,A0A1D8PCN8,GenBank,AOW25913,,,SC5314,PSY2,chromosome 1,,,,,PHI:9542,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,methyl methanesulfonate (MMS); H2O2; hydroxyurea; cisplatin,H2O2: CHEBI:16240; methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899,,,,,gene mutation,,,YVS,31644792,PubMed,10.1093/femsyr/foz075,FEMS Yeast Res. 2019 Oct 23. pii: foz075,jinrong532@163.com,"Deletion of PTC2 alone resulted in no significant change in cell virulence, but double deletion of PTC2 PPH3 significantly decreased virulence, while double deletions of either PTC2 PSY2 or PTC2 PSY4 caused increased in virulence.",J Feng 2019,2019,4 genes,Feng-2019-Genetic interaction between Ptc2 and,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14840,PHI:9542,UniProt,A0A1D8PRZ8,GenBank,AOW30911,,,SC5314,PTC2,chromosome R,,,,,PHI:9545,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,protein phosphatase,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,methyl methanesulfonate (MMS); H2O2; hydroxyurea; cisplatin,H2O2: CHEBI:16240; methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899,,,,,gene mutation,,,YVS,31644792,PubMed,10.1093/femsyr/foz075,FEMS Yeast Res. 2019 Oct 23. pii: foz075,jinrong532@163.com,"Deletion of PTC2 alone resulted in no significant change in cell virulence, but double deletion of PTC2 PPH3 significantly decreased virulence, while double deletions of either PTC2 PSY2 or PTC2 PSY4 caused increased in virulence.",J Feng 2019,2019,4 genes,Feng-2019-Genetic interaction between Ptc2 and,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14841,PHI:9545,UniProt,Q5AK01,GenBank,AOW29930,,,SC5314,PSY4,chromosome 5,,,,,PHI:9542,5476,Candida albicans,,RM1000,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,methyl methanesulfonate (MMS); H2O2; hydroxyurea; cisplatin,H2O2: CHEBI:16240; methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899,,,,,gene mutation,,,YVS,31644792,PubMed,10.1093/femsyr/foz075,FEMS Yeast Res. 2019 Oct 23. pii: foz075,jinrong532@163.com,"Deletion of PTC2 alone resulted in no significant change in cell virulence, but double deletion of PTC2 PPH3 significantly decreased virulence, while double deletions of either PTC2 PSY2 or PTC2 PSY4 caused increased in virulence.",J Feng 2019,2019,4 genes,Feng-2019-Genetic interaction between Ptc2 and,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14842,PHI:9546,UniProt,J4UIJ0,GenBank,EJP63372,,,ARSEF 2860,BbepnL-1 (BBA_07766),,,,,,,176275,Beauveria bassiana,,GXsk1011,white muscardine,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,endothiapepsin-like protein,,,,reduced virulence,,,,,,increased,,reduced; aberrant,,no,SDS; H2O2; Congo red; NaCl; calcofluor white,"SDS: CHEBI:8984; H2O2: CHEBI:16240; C,  Congo red: CHEBI:34653; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011",,,,,gene deletion: full; gene complementation,,,YVS,31715184,PubMed,10.1016/j.jip.2019.107277,J Invertebr Pathol. 2019 Nov 9:107277,canbl3312@126.com,The recombinant endothiapepsin-like protein showed enzyme activity and degraded the protein components of the silkworm cuticle.,C X Gu 2019,2019,1 gene,Gu-2019-Characterization of the endothiapepsin,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14843,PHI:9547,UniProt,G4N9S6,GenBank,EHA49583,,,70-15,Moarf6,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ADP-ribosylation factor 6,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14844,PHI:9548,UniProt,G4N3J3,GenBank,EHA52668,,,70-15,Moarl1,chromosome 3,,,Mogga1; Moarf1,UniProt: G4NE07; GenBank: EHA48542; UniProt: G4N8F9; GenBank: EHA51007,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ADP-ribosylation factor-like protein 1,,,,reduced virulence,,no,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14845,PHI:9549,UniProt,G4MV60,GenBank,EHA54075,,,70-15,Moarl3,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ADP-ribosylation factor family protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14846,PHI:9550,UniProt,A0A2L1CF02,GenBank,AVC05419,,,Guy11,Mocin4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ARF family GTPase,,,,reduced virulence,,,yes,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14847,PHI:9551,UniProt,G4MTV1,GenBank,EHA54745,,,70-15,Moarl8,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ADP-ribosylation factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14848,PHI:9552,UniProt,G4NE07,GenBank,EHA48542,,,70-15,Mogga1,chromosome 5,,,Moarl1; Moarf1,UniProt: G4N3J3; GenBank: EHA52668; UniProt: G4N8F9; GenBank: EHA51007,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ADP-ribosylation factor-binding protein,,,,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14849,PHI:9553,UniProt,G4N8F9,GenBank,EHA51007,,,70-15,Moarf1,chromosome 4,,,Moarl1; Mogga1,UniProt: G4N3J3; GenBank: EHA52668; UniProt: G4NE07; GenBank: EHA48542,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,eukaryotic peptide chain release factor subunit,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14850,PHI:9554,UniProt,P0CT16,GenBank,EHA50896,,,70-15,Mosar1,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,small COPII coat GTPase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14851,PHI:9547,UniProt,G4N9S6,GenBank,EHA49583,,,70-15,Moarf6,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ADP-ribosylation factor 6,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14852,PHI:9548,UniProt,G4N3J3,GenBank,EHA52668,,,70-15,Moarl1,chromosome 3,,,Mogga1; Moarf1,UniProt: G4NE07; GenBank: EHA48542; UniProt: G4N8F9; GenBank: EHA51007,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ADP-ribosylation factor-like protein 1,,,,reduced virulence,,no,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14853,PHI:9549,UniProt,G4MV60,GenBank,EHA54075,,,70-15,Moarl3,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ADP-ribosylation factor family protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14854,PHI:9550,UniProt,A0A2L1CF02,GenBank,AVC05419,,,Guy11,Mocin4,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ARF family GTPase,,,,reduced virulence,,,yes,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14855,PHI:9551,UniProt,G4MTV1,GenBank,EHA54745,,,70-15,Moarl8,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ADP-ribosylation factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14856,PHI:9552,UniProt,G4NE07,GenBank,EHA48542,,,70-15,Mogga1,chromosome 5,,,Moarl1; Moarf1,UniProt: G4N3J3; GenBank: EHA52668; UniProt: G4N8F9; GenBank: EHA51007,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ADP-ribosylation factor-binding protein,,,,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14857,PHI:9553,UniProt,G4N8F9,GenBank,EHA51007,,,70-15,Moarf1,chromosome 4,,,Moarl1; Mogga1,UniProt: G4N3J3; GenBank: EHA52668; UniProt: G4NE07; GenBank: EHA48542,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,eukaryotic peptide chain release factor subunit,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14858,PHI:9554,UniProt,P0CT16,GenBank,EHA50896,,,70-15,Mosar1,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,small COPII coat GTPase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31615964,PubMed,10.1128/mBio.02398-19,MBio. 2019 Oct 15;10(5). pii: e02398-19,zhgzhang@njau.edu.cn,"MoArl1, MoCin4, and MoGga1 were involved in pathogenicity through the regulation of host penetration and invasive hyphal growth.",S Zhang 2019,2019,8 genes,Zhang-2019-System-Wide Characterization of MoA,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14859,PHI:9555,UniProt,A0A0B6RPI1,GenBank,AJK45263,,,PG1,wbiF,chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,panicle,glycosyl transferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,hydrogen peroxide; polymyxin B; SDS,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31632220,PubMed,10.5423/PPJ.OA.04.2019.0124,Plant Pathol J. 2019 Oct;35(5):445-458,yseo2011@pusan.ac.kr,"The core OS-related gene, waaC, was required for the full virulence of B. glumae BGR1 to rice plants.",C Lee 2019,2019,5 genes,Lee-2019-Stress Tolerance and Virulence-Relate,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14860,PHI:9556,UniProt,A0A0B6RSX9,GenBank,AJK45264,,,PG1,wbiG,chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,panicle,UDP-glucose 4-epimerase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,hydrogen peroxide; polymyxin B; SDS,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31632220,PubMed,10.5423/PPJ.OA.04.2019.0124,Plant Pathol J. 2019 Oct;35(5):445-458,yseo2011@pusan.ac.kr,"The core OS-related gene, waaC, was required for the full virulence of B. glumae BGR1 to rice plants.",C Lee 2019,2019,5 genes,Lee-2019-Stress Tolerance and Virulence-Relate,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14861,PHI:9557,UniProt,A0A0B6RW42,GenBank,AJK45265,,,PG1,wbiH,chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,panicle,glycosyl transferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,hydrogen peroxide; polymyxin B; SDS,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31632220,PubMed,10.5423/PPJ.OA.04.2019.0124,Plant Pathol J. 2019 Oct;35(5):445-458,yseo2011@pusan.ac.kr,"The core OS-related gene, waaC, was required for the full virulence of B. glumae BGR1 to rice plants.",C Lee 2019,2019,5 genes,Lee-2019-Stress Tolerance and Virulence-Relate,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14862,PHI:9558,,no data found,,,,,,wbiI,chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,panicle,O-antigen,,,,unaffected pathogenicity,,,,,,,,wild type,,no,hydrogen peroxide; polymyxin B; SDS,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31632220,PubMed,10.5423/PPJ.OA.04.2019.0124,Plant Pathol J. 2019 Oct;35(5):445-458,yseo2011@pusan.ac.kr,"The core OS-related gene, waaC, was required for the full virulence of B. glumae BGR1 to rice plants.",C Lee 2019,2019,5 genes,Lee-2019-Stress Tolerance and Virulence-Relate,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14863,PHI:9559,UniProt,A0A2J9HCW0,GenBank,PNL02369,,,FDAARGOS_346,waaC,chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,panicle,lipopolysaccharide heptosyltransferase,,,,reduced virulence,,,,,,,,reduced,,no,hydrogen peroxide; polymyxin B; SDS,hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31632220,PubMed,10.5423/PPJ.OA.04.2019.0124,Plant Pathol J. 2019 Oct;35(5):445-458,yseo2011@pusan.ac.kr,"The core OS-related gene, waaC, was required for the full virulence of B. glumae BGR1 to rice plants.",C Lee 2019,2019,5 genes,Lee-2019-Stress Tolerance and Virulence-Relate,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14864,PHI:9560,UniProt,K3VKP6,GenBank,EKJ75402,,,CS3096,FpAda1 (FPSE_04421),,,,,,,101028,Fusarium pseudograminearum,,WZ2-8,Fusarium crown rot; Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Aikang 58,,,coleoptile,bZip transcription factor,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31696258,PubMed,10.1007/s00294-019-01042-1,Curr Genet. 2019 Nov 6,honglianli@sina.com,"Deletion of FpAda1 in F. pseudograminearum resulted in defects in hyphal growth, mycelial branching and conidia formation.",L Chen 2019,2019,1 gene,Chen-2019-The bZIP transcription factor FpAda1,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14865,PHI:9560,UniProt,K3VKP6,GenBank,EKJ75402,,,CS3096,FpAda1 (FPSE_04421),,,,,,,101028,Fusarium pseudograminearum,,WZ2-8,Fusarium crown rot; Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),,,,leaf,bZip transcription factor,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31696258,PubMed,10.1007/s00294-019-01042-1,Curr Genet. 2019 Nov 6,honglianli@sina.com,"Deletion of FpAda1 in F. pseudograminearum resulted in defects in hyphal growth, mycelial branching and conidia formation.",L Chen 2019,2019,1 gene,Chen-2019-The bZIP transcription factor FpAda1,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14866,PHI:9561,UniProt,G8BCG7,GenBank,CCE41832,,,CDC317,UME6,,tetO-UME6,,,,,5480,Candida parapsilosis,,,systemic candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; brain,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31619502,PubMed,10.1128/mSphere.00656-19,mSphere. 2019 Oct 16;4(5). pii: e00656-19,kadosh@uthscsa.edu,Both strains showed a dramatic reduction in organ fungal burden in response to UME6 expression.,M Banerjee 2019,2019,3 genes,Banerjee-2019-Filamentation Is Associated with,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14867,PHI:9561,,no data found,,,,,,UME6,,tetO-UME6,,,,,5482,Candida tropicalis,,,systemic candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; brain,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31619502,PubMed,10.1128/mSphere.00656-19,mSphere. 2019 Oct 16;4(5). pii: e00656-19,kadosh@uthscsa.edu,Both strains showed a dramatic reduction in organ fungal burden in response to UME6 expression.,M Banerjee 2019,2019,3 genes,Banerjee-2019-Filamentation Is Associated with,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14868,PHI:9562,,no data found,,,,,,nrg1,,,,,,,5482,Candida tropicalis,,,systemic candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; brain,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31619502,PubMed,10.1128/mSphere.00656-19,mSphere. 2019 Oct 16;4(5). pii: e00656-19,kadosh@uthscsa.edu,The nrg1Δ/Δ mutant showed significantly reduced fungal burden compared to the wild-type (WT) strain in both the kidneys and brain.,M Banerjee 2019,2019,3 genes,Banerjee-2019-Filamentation Is Associated with,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14869,PHI:9563,,no data found,,,,,,hgc1,,,,,,,5482,Candida tropicalis,,,systemic candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; brain,cyclin-like protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31619502,PubMed,10.1128/mSphere.00656-19,mSphere. 2019 Oct 16;4(5). pii: e00656-19,kadosh@uthscsa.edu,C. tropicalis hgc1Δ/Δ mutant showed slightly increased organ fungal burdens compared to those of the WT.,M Banerjee 2019,2019,3 genes,Banerjee-2019-Filamentation Is Associated with,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14870,PHI:9564,UniProt,B0XSF6,GenBank,EDP54642,,,A1163,LeuA (AFUB_027020),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,3-isopropylmalate dehydratase,,,leucine biosynthetic pathway,reduced virulence,,,,,,,reduced,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31694453,PubMed,10.1080/21505594.2019.1682760,Virulence. 2019 Dec;10(1):925-934,hubertus.haas@i-med.ac.at,"Compared to lack of LeuA, lack of LeuC resulted in increased leucine dependence, a growth defect during iron starvation and decreased expression of LeuB-regulated genes including genes involved in iron acquisition.",T Orasch 2019,2019,2 genes,Orasch-2019-The leucine biosynthetic pathway i,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14871,PHI:9565,UniProt,B0XN47,GenBank,EDP56737,,,A1163,LeuC (AFUB_014560),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,2-isopropylmalate synthase,,,leucine biosynthetic pathway,reduced virulence,,,,,,,reduced,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31694453,PubMed,10.1080/21505594.2019.1682760,Virulence. 2019 Dec;10(1):925-934,hubertus.haas@i-med.ac.at,"Compared to lack of LeuA, lack of LeuC resulted in increased leucine dependence, a growth defect during iron starvation and decreased expression of LeuB-regulated genes including genes involved in iron acquisition.",T Orasch 2019,2019,2 genes,Orasch-2019-The leucine biosynthetic pathway i,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14872,PHI:9565,UniProt,B0XN47,GenBank,EDP56737,,,A1163,LeuC (AFUB_014560),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,2-isopropylmalate synthase,,,leucine biosynthetic pathway,loss of pathogenicity,,,,,,,reduced,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31694453,PubMed,10.1080/21505594.2019.1682760,Virulence. 2019 Dec;10(1):925-934,hubertus.haas@i-med.ac.at,"Compared to lack of LeuA, lack of LeuC resulted in increased leucine dependence, a growth defect during iron starvation and decreased expression of LeuB-regulated genes including genes involved in iron acquisition.",T Orasch 2019,2019,2 genes,Orasch-2019-The leucine biosynthetic pathway i,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14873,PHI:9566,UniProt,D4GNZ9,GenBank,ADD78704,,,LMG 20103,hfq (PANA_RS17940),,,,,,,553,Pantoea ananatis,1378093,LMG 2665,center rot (onion),monocots,4679,Allium cepa (related: onion),,,,bulb,RNA-binding protein,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31572315,PubMed,10.3389/fmicb.2019.02075. eCollection 2019,Front Microbiol. 2019 Sep 11;10:2075,Teresa.Coutinho@up.ac.za,Inactivation of the hfq gene in P. ananatis LMG 2665T resulted in a significant reduction of quorum sensing signal molecule acyl-homoserine lactone (AHL) production and biofilm formation.,G Y Shin 2019,2019,1 gene,Shin-2019-Functional Characterization of a Glo,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14874,PHI:9567,UniProt,B8NNI1,GenBank,EED48569,,,,crzA (AFLA_127920),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,aspergillosis,monocots,4577,Zea mays (related: maize),subsp. mays,,,kernel,C2H2-type transcription factor,,,calcineurin pathway,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol; NaCl; KCl; CaCl2; calcofluor white; Congo red; H2O2,sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31569747,PubMed,10.3390/toxins11100567,Toxins (Basel). 2019 Sep 27;11(10). pii: E567,13mjkim@gmail.com,"Absence of crzA resulted in decreased colony growth, the number of conidia, sclerocia production and reduced aflatoxin production.",S Y Lim 2019,2019,1 gene,Lim-2019-Function of crzA in Fungal Developmen,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14875,PHI:9568,UniProt,A0A4R6B9E2,GenBank,ADV85270,,,MO6-24/O,VvHmpA (VVMO6_00248),chromosome I,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage cell line,NO-inducible flavohemoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,31616401,PubMed,10.3389/fmicb.2019.02208,Front Microbiol. 2019 Sep 24;10:2208,choish@snu.ac.kr,The cytotoxicity and survival of the VvhmpA mutant infecting the NO-producing murine macrophage cells were lower than those of the wild type.,D Kim 2019,2019,1 gene,Kim-2019-Transcriptomic Identification and Bio,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14876,PHI:9568,UniProt,A0A4R6B9E2,GenBank,ADV85270,,,MO6-24/O,VvHmpA (VVMO6_00248),chromosome I,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,NO-inducible flavohemoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,YVS,31616401,PubMed,10.3389/fmicb.2019.02208,Front Microbiol. 2019 Sep 24;10:2208,choish@snu.ac.kr,The mouse lethality of the VvhmpA mutant was reduced compared to that of the parental wild type.,D Kim 2019,2019,1 gene,Kim-2019-Transcriptomic Identification and Bio,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14877,PHI:9569,UniProt,C9YRB0,GenBank,CBE06969,,,R20291,CmrR (CDR20291_3128),,,,,,,1496,Clostridioides difficile,645463,R20291,nosocomial diarrhea,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,feces; cecum,two-component response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31658249,PubMed,10.1371/journal.pbio.3000379,PLoS Biol. 2019 Oct 28;17(10):e3000379,Rita_tamayo@med.unc.edu,"CmrR, but not CmrT, was important for the ability of C. difficile to colonize the intestinal tract and cause disease in the hamster model.",E M Garrett 2019,2019,2 genes,Garrett-2019-Phase variation of a signal trans,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14878,PHI:9570,UniProt,C9YRA8,GenBank,CBE06965,,,R20291,CmrT (CDR20291_3126),,,,,,,1496,Clostridioides difficile,645463,R20291,nosocomial diarrhea,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,feces; cecum,two-component response regulator,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31658249,PubMed,10.1371/journal.pbio.3000379,PLoS Biol. 2019 Oct 28;17(10):e3000379,Rita_tamayo@med.unc.edu,"CmrR, but not CmrT, was important for the ability of C. difficile to colonize the intestinal tract and cause disease in the hamster model.",E M Garrett 2019,2019,2 genes,Garrett-2019-Phase variation of a signal trans,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14879,PHI:9571,UniProt,A0A0E1DUV6,GenBank,AIA68450,,,CY,SezV (WP_038674722.1),,,,,,,1336,Streptococcus equi,1051072,subsp. zooepidemicus strain C74-63,septicemia; meningitis; mastitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,brain; blood,AraC family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31641092,PubMed,10.1128/mBio.02500-19,MBio. 2019 Oct 22;10(5). pii: e02500-19,mazhe@njau.edu.cn,SEZ strains with inactivating mutations in either sezV or szM were highly attenuated in a mouse model of infection.,J D D'Gama 2019,2019,2 genes,D'Gama-2019-A Conserved Streptococcal Virulenc,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14880,PHI:9572,UniProt,A0A0E1DVG8,GenBank,AIA68451,,,CY,szM (WP_014623570.1),,,,,,,1336,Streptococcus equi,1051072,subsp. zooepidemicus strain C74-63,septicemia; meningitis; mastitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,brain; blood,peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31641092,PubMed,10.1128/mBio.02500-19,MBio. 2019 Oct 22;10(5). pii: e02500-19,mazhe@njau.edu.cn,SEZ strains with inactivating mutations in either sezV or szM were highly attenuated in a mouse model of infection.,J D D'Gama 2019,2019,2 genes,D'Gama-2019-A Conserved Streptococcal Virulenc,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14881,PHI:9573,UniProt,B2RKZ9,GenBank,BAG34044,,,ATCC 33277,php1 (PGN_1525),,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone,tyrosine phosphatase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31551334,PubMed,10.1128/mBio.02004-19,MBio. 2019 Sep 24;10(5). pii: e02004-19,rich.lamont@louisville.edu,Loss of Php1 rendered P. gingivalis nonvirulent in an animal model of periodontal disease.,Y J Jung 2019,2019,1 gene,Jung-2019-Porphyromonas gingivalis Tyrosine Ph,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14882,PHI:9574,UniProt,Q7VWL6,GenBank,CAE42471,,,Tohama I,Hfq,,,,,,,520,Bordetella pertussis,257313,Tohama I,pertussis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,RNA-binding protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31669358,PubMed,10.1016/j.jprot.2019.103559,J Proteomics. 2020 Jan 16;211:103559,mer@quimica.unlp.edu.ar,The increase of B. pertussis oxidative stress tolerance in response to low iron availability depended on Hfq.,J A Hayes 2019,2019,1 gene,Alvarez Hayes-2019-Hfq modulates global protei,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14883,PHI:9575,UniProt,A0A4Q2TW30,GenBank,QCH84387,,,FWSEC0004,OvrA,,,,,,,562,Escherichia coli,83334,serotype O157:H7,diarrhea,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,putative transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31630185,PubMed,10.1093/infdis/jiz458,J Infect Dis. 2019 Sep 6. pii: jiz458,yangbin@nankai.edu.cn,The ovrA mutant exhibited significantly decreased host cell adherence and reduced colonization in the mouse intestinal tract.,B Liu 2019,2019,1 gene,Liu-2019-Transcriptional Activator OvrA Encode,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14884,PHI:9575,UniProt,A0A4Q2TW30,GenBank,QCH84387,,,FWSEC0004,OvrA,,,,,,,562,Escherichia coli,83334,serotype O157:H7,diarrhea,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,putative transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31630185,PubMed,10.1093/infdis/jiz458,J Infect Dis. 2019 Sep 6. pii: jiz458,yangbin@nankai.edu.cn,The ovrA mutant exhibited significantly decreased host cell adherence and reduced colonization in the mouse intestinal tract.,B Liu 2019,2019,1 gene,Liu-2019-Transcriptional Activator OvrA Encode,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14885,PHI:9575,UniProt,A0A4Q2TW30,GenBank,QCH84387,,,FWSEC0004,OvrA,,,,,,,562,Escherichia coli,83334,serotype O157:H7,diarrhea,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ileum; colon,putative transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,31630185,PubMed,10.1093/infdis/jiz458,J Infect Dis. 2019 Sep 6. pii: jiz458,yangbin@nankai.edu.cn,The ovrA mutant exhibited significantly decreased host cell adherence and reduced colonization in the mouse intestinal tract.,B Liu 2019,2019,1 gene,Liu-2019-Transcriptional Activator OvrA Encode,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14886,PHI:9576,UniProt,B4E5A2,GenBank,CAR50527,,,J2315,paaA,chromosome 1,,,,,PHI:9577; PHI:9578; PHI:9579; PHI:9580,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetic acid degradation protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,"While loss of PaaABCDE decreased virulence, deletion of the paaK genes resulted in a more virulent phenotype than the wild type strain.",T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14887,PHI:9577,UniProt,A0A088U4K2,GenBank,AIO32166,,,DDS 22E-1,paaB,chromosome 1,,,,,PHI:9576; PHI:9578; PHI:9579; PHI:9580,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate degradation putative enoyl-CoA hydratase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,"While loss of PaaABCDE decreased virulence, deletion of the paaK genes resulted in a more virulent phenotype than the wild type strain.",T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14888,PHI:9578,UniProt,B4E5A0,GenBank,CAR50525,,,J2315,paaC,chromosome 1,,,,,PHI:9576; PHI:9577; PHI:9579; PHI:9580,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetic acid degradation protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,"While loss of PaaABCDE decreased virulence, deletion of the paaK genes resulted in a more virulent phenotype than the wild type strain.",T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14889,PHI:9579,UniProt,A0A088UAI6,GenBank,AIO34196,,,DDS 22E-1,paaD,chromosome 1,,,,,PHI:9576; PHI:9577; PHI:9578; PHI:9580,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetic acid degradation protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,"While loss of PaaABCDE decreased virulence, deletion of the paaK genes resulted in a more virulent phenotype than the wild type strain.",T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14890,PHI:9580,UniProt,B4E598,GenBank,CAR50523,,,J2315,paaE,chromosome 1,,,,,PHI:9576; PHI:9577; PHI:9578; PHI:9579,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative phenylacetic acid degradation NADH oxidoreductase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,"While loss of PaaABCDE decreased virulence, deletion of the paaK genes resulted in a more virulent phenotype than the wild type strain.",T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14891,PHI:9576,UniProt,B4E5A2,GenBank,CAR50527,,,J2315,paaA,chromosome 1,,,,,PHI:9577; PHI:9578; PHI:9579; PHI:9580; PHI:9581,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetic acid degradation protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14892,PHI:9577,UniProt,A0A088U4K2,GenBank,AIO32166,,,DDS 22E-1,paaB,chromosome 1,,,,,PHI:9576; PHI:9578; PHI:9579; PHI:9580; PHI:9581,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate degradation putative enoyl-CoA hydratase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14893,PHI:9578,UniProt,B4E5A0,GenBank,CAR50525,,,J2315,paaC,chromosome 1,,,,,PHI:9576; PHI:9577; PHI:9579; PHI:9580; PHI:9581,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetic acid degradation protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14894,PHI:9579,UniProt,A0A088UAI6,GenBank,AIO34196,,,DDS 22E-1,paaD,chromosome 1,,,,,PHI:9576; PHI:9577; PHI:9578; PHI:9580; PHI:9581,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetic acid degradation protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14895,PHI:9580,UniProt,B4E598,GenBank,CAR50523,,,J2315,paaE,chromosome 1,,,,,PHI:9576; PHI:9577; PHI:9578; PHI:9579; PHI:9581,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative phenylacetic acid degradation NADH oxidoreductase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14896,PHI:9581,UniProt,B4EMD2,GenBank,CAR55728,,,J2315,cepI,chromosome 2,,,,,PHI:9576; PHI:9577; PHI:9578; PHI:9579; PHI:9580,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,N-acylhomoserine lactone synthase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14897,PHI:9576,UniProt,B4E5A2,GenBank,CAR50527,,,J2315,paaA,chromosome 1,,,,,PHI:9577; PHI:9578; PHI:9579; PHI:9580; PHI:9582,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetic acid degradation protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14898,PHI:9577,UniProt,A0A088U4K2,GenBank,AIO32166,,,DDS 22E-1,paaB,chromosome 1,,,,,PHI:9576; PHI:9578; PHI:9579; PHI:9580; PHI:9582,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate degradation putative enoyl-CoA hydratase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14899,PHI:9578,UniProt,B4E5A0,GenBank,CAR50525,,,J2315,paaC,chromosome 1,,,,,PHI:9576; PHI:9577; PHI:9579; PHI:9580; PHI:9582,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetic acid degradation protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14900,PHI:9579,UniProt,A0A088UAI6,GenBank,AIO34196,,,DDS 22E-1,paaD,chromosome 1,,,,,PHI:9576; PHI:9577; PHI:9578; PHI:9580; PHI:9582,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetic acid degradation protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14901,PHI:9580,UniProt,B4E598,GenBank,CAR50523,,,J2315,paaE,chromosome 1,,,,,PHI:9576; PHI:9577; PHI:9578; PHI:9579; PHI:9582,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative phenylacetic acid degradation NADH oxidoreductase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14902,PHI:9582,UniProt,B4EMD0,GenBank,CAR55726,,,J2315,cepR,chromosome 2,,,,,PHI:9576; PHI:9577; PHI:9578; PHI:9579; PHI:9580,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,N-acylhomoserine lactone dependent regulatory protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,Removal of paaABCDE in the cepI mutant and cepR mutant did not impact its attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14903,PHI:9583,UniProt,A0A1V2Y2U7,GenBank,ONU87697,,,VC14762,paaK1,,,,,,PHI:9584,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate-coenzyme A ligase,,,phenylalanine catabolism,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,"While loss of PaaABCDE decreased virulence, deletion of the paaK genes resulted in a more virulent phenotype than the wild type strain.",T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14904,PHI:9584,UniProt,A0A1V2WCB4,GenBank,ONU93896,,,VC14762,paaK2,,,,,,PHI:9583,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate-coenzyme A ligase,,,phenylalanine catabolism,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,"While loss of PaaABCDE decreased virulence, deletion of the paaK genes resulted in a more virulent phenotype than the wild type strain.",T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14905,PHI:9583,UniProt,A0A1V2Y2U7,GenBank,ONU87697,,,VC14762,paaK1,,,,,,PHI:9584; PHI:9581,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate-coenzyme A ligase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,A low virulence cepR mutant reverted to a virulent phenotype upon removal of the paaK genes.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14906,PHI:9584,UniProt,A0A1V2WCB4,GenBank,ONU93896,,,VC14762,paaK2,,,,,,PHI:9583; PHI:9581,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate-coenzyme A ligase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,A low virulence cepR mutant reverted to a virulent phenotype upon removal of the paaK genes.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14907,PHI:9581,UniProt,B4EMD2,GenBank,CAR55728,,,J2315,cepI,chromosome 2,,,,,PHI:9583; PHI:9584,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,N-acylhomoserine lactone synthase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,A low virulence cepR mutant reverted to a virulent phenotype upon removal of the paaK genes.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14908,PHI:9583,UniProt,A0A1V2Y2U7,GenBank,ONU87697,,,VC14762,paaK1,,,,,,PHI:9584; PHI:9582,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate-coenzyme A ligase,,,phenylalanine catabolism,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,A low virulence cepR mutant reverted to a virulent phenotype upon removal of the paaK genes.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14909,PHI:9584,UniProt,A0A1V2WCB4,GenBank,ONU93896,,,VC14762,paaK2,,,,,,PHI:9583; PHI:9582,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate-coenzyme A ligase,,,phenylalanine catabolism,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,A low virulence cepR mutant reverted to a virulent phenotype upon removal of the paaK genes.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14910,PHI:9582,UniProt,B4EMD0,GenBank,CAR55726,,,J2315,cepR,chromosome 2,,,,,PHI:9583; PHI:9584,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,N-acylhomoserine lactone dependent regulatory protein,,,phenylalanine catabolism,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,A low virulence cepR mutant reverted to a virulent phenotype upon removal of the paaK genes.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14911,PHI:9583,UniProt,A0A1V2Y2U7,GenBank,ONU87697,,,VC14762,paaK1,,,,,,,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate-coenzyme A ligase,,,phenylalanine catabolism,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,"While loss of PaaABCDE decreased virulence, deletion of the paaK genes resulted in a more virulent phenotype than the wild type strain.",T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14912,PHI:9584,UniProt,A0A1V2WCB4,GenBank,ONU93896,,,VC14762,paaK2,,,,,,,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phenylacetate-coenzyme A ligase,,,phenylalanine catabolism,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,"While loss of PaaABCDE decreased virulence, deletion of the paaK genes resulted in a more virulent phenotype than the wild type strain.",T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14913,PHI:9581,UniProt,B4EMD2,GenBank,CAR55728,,,J2315,cepI,chromosome 2,,,,,,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,N-acylhomoserine lactone synthase,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,The cepI and cepR mutantions in wild type had attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14914,PHI:9582,UniProt,B4EMD0,GenBank,CAR55726,,,J2315,cepR,chromosome 2,,,,,,95486,Burkholderia cenocepacia,,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,N-acylhomoserine lactone dependent regulatory protein,,,phenylalanine catabolism,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31585996,PubMed,10.1128/AEM.01594-19,Appl Environ Microbiol. 2019 Oct 4. pii: AEM.01594-19,Silvia.Cardona@umanitoba.ca,The cepI and cepR mutantions in wild type had attenuated phenotype.,T J Lightly 2019,2019,9 genes,"Lightly-2019-Phenylacetyl-CoA, not phenylaceti",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14915,PHI:9585,UniProt,G7TKV5,GenBank,AEQ95811,,,BLS256,XOC_1643,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,outer membrane channel protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31581193,PubMed,10.1371/journal.pone.0218844,PLoS One. 2019 Oct 3;14(10):e0218844,ryc@zjnu.cn,"The XOC_1643, XOC_3249 and XOC_2868 mutants clearly displayed a greater sensitivity to H2O2 than did the BLS256 wild-type, however, the XOC_1946 mutant showed a greater resistance to H2O2.",Y Fang 2019,2019,4 genes,Fang-2019-Transcriptome analysis of Xanthomona,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14916,PHI:9586,UniProt,G7TB42,GenBank,AEQ97343,,,BLS256,XOC_3249,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,membrane protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31581193,PubMed,10.1371/journal.pone.0218844,PLoS One. 2019 Oct 3;14(10):e0218844,ryc@zjnu.cn,"The XOC_1643, XOC_3249 and XOC_2868 mutants clearly displayed a greater sensitivity to H2O2 than did the BLS256 wild-type, however, the XOC_1946 mutant showed a greater resistance to H2O2.",Y Fang 2019,2019,4 genes,Fang-2019-Transcriptome analysis of Xanthomona,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14917,PHI:9587,UniProt,G7TK41,GenBank,AEQ96974,,,BLS256,XOC_2868,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31581193,PubMed,10.1371/journal.pone.0218844,PLoS One. 2019 Oct 3;14(10):e0218844,ryc@zjnu.cn,"The XOC_1643, XOC_3249 and XOC_2868 mutants clearly displayed a greater sensitivity to H2O2 than did the BLS256 wild-type, however, the XOC_1946 mutant showed a greater resistance to H2O2.",Y Fang 2019,2019,4 genes,Fang-2019-Transcriptome analysis of Xanthomona,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14918,PHI:9588,UniProt,G7TBM8,GenBank,AEQ96099,,,BLS256,XOC_1946,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,TonB-dependent receptor,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31581193,PubMed,10.1371/journal.pone.0218844,PLoS One. 2019 Oct 3;14(10):e0218844,ryc@zjnu.cn,"The XOC_1643, XOC_3249 and XOC_2868 mutants clearly displayed a greater sensitivity to H2O2 than did the BLS256 wild-type, however, the XOC_1946 mutant showed a greater resistance to H2O2.",Y Fang 2019,2019,4 genes,Fang-2019-Transcriptome analysis of Xanthomona,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14919,PHI:9589,UniProt,A0A0D2XIB5,GenBank,KNA99961,,,4287,pmt1 (FOXG_03668),chromosome 8,,,,,,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain CGMCC3.2830,Fusarium wilt,eudicots,3659,Cucumis sativus (related: cucumber),cv. Zhong Nong 16,,,seedling; root,dolichyl-phosphate-mannose-protein mannosyltransferase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,SDS; Congo red; calcofluor white; D-sorbitol; polyoxin; tunicamycin; DTT; brefeldin A,SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; D-sorbitol: CHEBI:17924; polyoxin: CHEBI:26194; tunicamycin: CHEBI:29699; DTT: CHEBI:42170; brefeldin A: CHEBI:48080,,,,,gene deletion: full,,,YVS,31648060,PubMed,10.1016/j.fgb.2019.103285,Fungal Genet Biol. 2019 Oct 21;134:103285,jinc@im.ac.cn,"PMTs were vital for cell wall integrity, morphogenesis, and virulence.",Y Xu 2019,2019,3 genes,Xu-2019-Genetical and O-glycoproteomic analyse,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14920,PHI:9590,UniProt,A0A0D2X980,GenBank,KNA94356,,,4287,pmt4 (FOXG_00440),chromosome 1,,,,,,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain CGMCC3.2830,Fusarium wilt,eudicots,3659,Cucumis sativus (related: cucumber),cv. Zhong Nong 16,,,seedling; root,dolichyl-phosphate-mannose-protein mannosyltransferase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,SDS; Congo red; calcofluor white; D-sorbitol; polyoxin; tunicamycin; DTT; brefeldin A,SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; D-sorbitol: CHEBI:17924; polyoxin: CHEBI:26194; tunicamycin: CHEBI:29699; DTT: CHEBI:42170; brefeldin A: CHEBI:48080,,,,,gene deletion: full,,,YVS,31648060,PubMed,10.1016/j.fgb.2019.103285,Fungal Genet Biol. 2019 Oct 21;134:103285,jinc@im.ac.cn,"PMTs were vital for cell wall integrity, morphogenesis, and virulence.",Y Xu 2019,2019,3 genes,Xu-2019-Genetical and O-glycoproteomic analyse,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14921,PHI:9591,UniProt,A0A0J9VK23,GenBank,KNB11180,,,4287,pmt2 (FOXG_11176),chromosome 1,pNiiA-pmt2 (conditional mutant by replacing the native pmt2 promoter with the niiA promoter),,,,,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain CGMCC3.2830,Fusarium wilt,eudicots,3659,Cucumis sativus (related: cucumber),cv. Zhong Nong 16,,,seedling; root,dolichyl-phosphate-mannose-protein mannosyltransferase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,SDS; Congo red; calcofluor white; D-sorbitol; polyoxin; tunicamycin; DTT; brefeldin A,SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; D-sorbitol: CHEBI:17924; polyoxin: CHEBI:26194; tunicamycin: CHEBI:29699; DTT: CHEBI:42170; brefeldin A: CHEBI:48080,,,,,promoter mutation,,,YVS,31648060,PubMed,10.1016/j.fgb.2019.103285,Fungal Genet Biol. 2019 Oct 21;134:103285,jinc@im.ac.cn,"PMTs were vital for cell wall integrity, morphogenesis, and virulence.",Y Xu 2019,2019,3 genes,Xu-2019-Genetical and O-glycoproteomic analyse,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14922,PHI:9592,UniProt,P26471,GenBank,AAA27206,,,LT2,rfaL,,,,,,,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,salmonellosis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,small intestine; mesenteric lymph node; liver; spleen; lung; blood,O-antigen ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31540295,PubMed,10.3390/toxins11090534,Toxins (Basel). 2019 Sep 13;11(9). pii: E534,splichalova@gnotobio.cz,The absence of O-antigen resulted in residual virulence but the absence of an outer core of LPS resulted in complete avirulence.,A Splichalova 2019,2019,3 genes,Splichalova-2019-Impact of the Lipopolysacchar,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14923,PHI:9593,UniProt,H9L435,GenBank,AAL22581,,,LT2,rfaG,,,,,,,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,salmonellosis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,small intestine; mesenteric lymph node; liver; spleen; lung; blood,glucosyltransferase I,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31540295,PubMed,10.3390/toxins11090534,Toxins (Basel). 2019 Sep 13;11(9). pii: E534,splichalova@gnotobio.cz,The absence of O-antigen resulted in residual virulence but the absence of an outer core of LPS resulted in complete avirulence.,A Splichalova 2019,2019,3 genes,Splichalova-2019-Impact of the Lipopolysacchar,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14924,PHI:9594,UniProt,P26469,GenBank,AAL22571,,,LT2,rfaC,,,,,,,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,salmonellosis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,small intestine; mesenteric lymph node; liver; spleen; lung; blood,heptosyl transferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31540295,PubMed,10.3390/toxins11090534,Toxins (Basel). 2019 Sep 13;11(9). pii: E534,splichalova@gnotobio.cz,The absence of O-antigen resulted in residual virulence but the absence of an outer core of LPS resulted in complete avirulence.,A Splichalova 2019,2019,3 genes,Splichalova-2019-Impact of the Lipopolysacchar,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14925,PHI:9595,UniProt,A0A0K0M9E0,GenBank,AJW67288,,,NXY61,Bx-tlp-1,,,,,,,6326,Bursaphelenchus xylophilus,,NXY61,pine wilt,seed plants,88730,Pinus massoniana (related: chinese red pine),,,,stem,thaumatin-like protein-1,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31573422,PubMed,10.1094/PHYTO-03-19-0082-R,Phytopathology. 2019 Nov;109(11):1949-1956,lyx020419@caf.ac.cn,"Bx-tlp-1 was crucial for B. xylophilus, not only because it influenced nematode reproduction but also because it influenced the extent of PWD symptoms.",F Meng 2019,2019,1 gene,Meng-2019-Thaumatin-Like Protein-1 Gene (Bx-tl,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14926,PHI:9596,UniProt,P9WQJ1,GenBank,CCP44029,,,H37Rv,Rv1273c,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,ABC transporter,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,heterologous expression,,,YVS,31593717,PubMed,10.1016/j.ijbiomac.2019.09.103 0141-8130,Int J Biol Macromol. 2019 Oct 5. pii: S0141-8130(19)33691-8,shampa_anupurba@yahoo.co.in,Expression of Rv1273c resulted in enhanced intracellular survival of of M. smegmatis in macrophage as well as modified cell wall architecture.,S Gupta 2019,2019,1 gene,"Gupta-2019-Rv1273c, an ABC transporter of Myco",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14927,PHI:9597,UniProt,B2HE92,GenBank,ACC41372,,,M,pecA (MMAR_2933),,,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),Casper,,,larva,aspartic acid protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31662454,PubMed,10.1128/mBio.01951-19,MBio. 2019 Oct 29;10(5). pii: e01951-19,c.kuijl@vumc.nl,Mutants lacking PecA showed growth attenuation in vivo.,M J Burggraaf 2019,2019,1 gene,Burggraaf-2019-Type VII Secretion Substrates o,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14928,PHI:9597,UniProt,B2HE92,GenBank,ACC41372,,,M,pecA (MMAR_2933),,,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,aspartic acid protease,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31662454,PubMed,10.1128/mBio.01951-19,MBio. 2019 Oct 29;10(5). pii: e01951-19,c.kuijl@vumc.nl,Mutants lacking PecA showed growth attenuation in vivo.,M J Burggraaf 2019,2019,1 gene,Burggraaf-2019-Type VII Secretion Substrates o,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14929,PHI:9597,UniProt,B2HE92,GenBank,ACC41372,,,M,pecA (MMAR_2933),,,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,aspartic acid protease,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31662454,PubMed,10.1128/mBio.01951-19,MBio. 2019 Oct 29;10(5). pii: e01951-19,c.kuijl@vumc.nl,Mutants lacking PecA showed growth attenuation in vivo.,M J Burggraaf 2019,2019,1 gene,Burggraaf-2019-Type VII Secretion Substrates o,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14930,PHI:9598,UniProt,C7LAK4,GenBank,ACU47539,,,CCM 4915,wbkE (BMI_I539),chromosome 1,,,,,,444163,Brucella microti,568815,CCM4915,brucellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774 cell,glycosyltransferase,,,lipopolysaccharide (LPS) O-polysaccharide biosynthesis,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31635539,PubMed,10.1080/21505594.2019.1682762,Virulence. 2019 Dec;10(1):868-878,stephan.kohler@irim.cnrs.fr,"A spontaneous rough (R) mutant strain formed due to the deletion of wbkE gene, showed increased macrophage colonization and was non-lethal in murine infections. macrophage-like cells",S Ouahrani 2019,2019,1 gene,Ouahrani-Bettac-2019-Lethality of Brucella mic,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14931,PHI:9598,UniProt,C7LAK4,GenBank,ACU47539,,,CCM 4915,wbkE (BMI_I539),chromosome 1,,,,,,29461,Brucella suis,204722,1330,brucellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774 cell,glycosyltransferase,,,lipopolysaccharide (LPS) O-polysaccharide biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31635539,PubMed,10.1080/21505594.2019.1682762,Virulence. 2019 Dec;10(1):868-878,stephan.kohler@irim.cnrs.fr,"A spontaneous rough (R) mutant strain formed due to the deletion of wbkE gene, showed increased macrophage colonization and was non-lethal in murine infections. macrophage-like cells",S Ouahrani 2019,2019,1 gene,Ouahrani-Bettac-2019-Lethality of Brucella mic,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14932,PHI:9598,UniProt,C7LAK4,GenBank,ACU47539,,,CCM 4915,wbkE (BMI_I539),chromosome 1,,,,,,444163,Brucella microti,568815,CCM4915,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,glycosyltransferase,,,lipopolysaccharide (LPS) O-polysaccharide biosynthesis,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31635539,PubMed,10.1080/21505594.2019.1682762,Virulence. 2019 Dec;10(1):868-878,stephan.kohler@irim.cnrs.fr,"A spontaneous rough (R) mutant strain formed due to the deletion of wbkE gene, showed increased macrophage colonization and was non-lethal in murine infections.",S Ouahrani 2019,2019,1 gene,Ouahrani-Bettac-2019-Lethality of Brucella mic,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14933,PHI:9599,UniProt,Q9I730,GenBank,AE004449_1,,,PAO1,psCA1,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,β-carbonic anhydrase,,,,reduced virulence,,,,,,,,,,no,3-aminobenzene sulfonamide; acetazolamide; sulfamide; CaCl2,3-aminobenzene sulfonamide: CAS:98-18-0; acetazolamide: CHEBI:27690; sulfamide: CHEBI:29368; CaCl2: CHEBI:3312,,,,,gene deletion: full,,,YVS,31589941,PubMed,10.1016/j.ceca.2019.102080,Cell Calcium. 2019 Sep 27;84:102080,m.patrauchan@okstate.edu,"β-CA psCA1 in P. aeruginosa contributed to virulence likely by enabling calcium salt deposition, which can be partially controlled by inhibiting its catalytic activity.",S R Lotlikar 2019,2019,1 gene,Lotlikar-2019-Pseudomonas aeruginosa beta-carb,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14934,PHI:9600,UniProt,A0A384JKP5,GenBank,ATZ51041.1,,,B05.10,Bcgpr3,chromosome BCIN06,,,,,,40559,Botrytis cinerea,,FJ1-3,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hongfen,,,fruit,G-protein-coupled receptor,,,,reduced virulence,,,,,,,,,,no,benzaldehyde; ethylene,benzaldehyde: CHEBI:17169; ethylene: CHEBI:29362,,,,,gene mutation,,,YVS,31693347,PubMed,10.1021/acs.jafc.9b05778,J Agric Food Chem. 2019 Nov 6,zhong591@fafu.edu.cn,"The inactivated BcGPR3 failed to transmit signals to the cAMP signal pathway, reducing the pathogenic effects of B. cinerea on tomato fruits.",Y Lin 2019,2019,1 gene,Lin-2019-Ethylene and benzaldehyde emitted fro,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14935,PHI:9601,UniProt,A0A0E1M219,GenBank,AJF56459,,,1303,RstA,,,,,,,562,Escherichia coli,,serotype O157:H7,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,two-component response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31695752,PubMed,10.1186/s13099-019-0335-4,Gut Pathog. 2019 Nov 1;11:53,yangbin@nankai.edu.cn,Biofilm formation was significantly increased in the ΔrstA mutant compared to that in the EHEC O157 WT.,Y Liu 2019,2019,1 gene,"Liu-2019-RstA, a two-component response regula",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14936,PHI:9601,UniProt,A0A0E1M219,GenBank,AJF56459,,,1303,RstA,,,,,,,562,Escherichia coli,,serotype O157:H7,infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,two-component response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31695752,PubMed,10.1186/s13099-019-0335-4,Gut Pathog. 2019 Nov 1;11:53,yangbin@nankai.edu.cn,The deletion of rstA significantly reduced bacterial adherence to HeLa cells compared with that of the EHEC O157 WT.,Y Liu 2019,2019,1 gene,"Liu-2019-RstA, a two-component response regula",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14937,PHI:9602,UniProt,I1RC07,GenBank,XP_011316870,,,PH-1; NRRL 31084,Ars2 (FGSG_01106),chromosome 1,,,FgCbp80 (FGSG_05488); FgCbp20 (FGSG_07328),UniProt: I1RNB8; GenBank: CEF86131; UniProt: I1RT35; GenBank: CEF85203,,5518,Fusarium graminearum,449239,Z-3639,head blight (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,inflorescence,arsenite-resistance protein,,,,reduced virulence,,,,,,defective,reduced; aberrant,reduced; aberrant,reduced,no,,,,,,,gene mutation; gene complementation,,,YVS,31681199,PubMed,10.3389/fmicb.2019.02326,Front Microbiol. 2019 Oct 15;10:2326,sja815@ssu.ac.kr,"Fgars2 mutants were irregular in nuclear division, and conidial germination was significantly retarded, causing the fungus to manifest its hypersensitive phenotypes under DNA damage stress.",D C Bui 2019,2019,1 gene,Bui-2019-ARS2 Plays Diverse Roles in DNA Damag,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14938,PHI:9603,UniProt,A4VX44,GenBank,ABP90683,,,05ZYH33,SSU05_1717 (hp1717),,,,,,,1307,Streptococcus suis,391295,05ZY,streptococcal toxic shock-like syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; liver; spleen; kidney,predicted periplasmic solute-binding protein,,,,reduced virulence,,,,,,,,,,no,SB203580; SP600125; pyrrolidine dithiocarbamate; LY294002; U0126,SB203580: CHEBI:90705; SP600125: CHEBI:90695; pyrrolidine dithiocarbamate: CHEBI:78782; LY294002: CHEBI:65329; U0126: CHEBI:90693,,,,,gene deletion: full,,,YVS,31684161,PubMed,10.3390/microorganisms7110522,Microorganisms. 2019 Nov 3;7(11),jinmeilin@mail.hzau.edu.cn,"The deletion of hp1717 in SS2 reduced the lethality, pro-inflammatory activity, bacterial loads in mice and displayed reduced resistance to whole-blood killing.",L Liu 2019,2019,1 gene,Liu-2019-HP1717 Contributes to Streptococcus s,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14939,PHI:9604,UniProt,P0ACN8,GenBank,AAN83315,,,CFT073,CytR,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,primates,9606,Homo sapiens (related: human),5637 cell line,,,bladder,HTH-type transcriptional repressor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption,,,YVS,31677792,PubMed,10.1016/j.bbrc.2019.10.165,Biochem Biophys Res Commun. 2019 Oct 30,hirakawa@gunma-u.ac.jp,The cytR mutant exhibited higher motility and promoted bacterial aggregation within the bladder epithelial cells.,H Hirakawa 2019,2019,1 gene,"Hirakawa-2019-Roles of CytR, an anti-activator",BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14940,PHI:9605,,no data found,GenBank,MGG_14621.6,,,,MoSDT1,,,,,,,318829,Magnaporthe oryzae,,95234I-1b,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Ilimi,,,leaf,C2H2 transcriptionFactor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; other evidence: transgenic plants,,,YVS,31557947,PubMed,10.3390/ijms20194762,Int J Mol Sci. 2019 Sep 25;20(19),yangjing@ynau.edu.cn,"Transgenic overexpression of MoSDT1 confered improved rice blast resistance in rice, through modulation of callose deposition, ROS accumulation, the expression of defense-related genes, and the accumulation of some primary metabolites.",C Wang 2019,2019,1 gene,Wang-2019-Overexpression of Magnaporthe Oryzae,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14941,PHI:9606,UniProt,Q0TY40,GenBank,EAT77040,,,SN15,PnPf2,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Halberd,,,leaf,Zn2Cys6 transcription factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,31685928,PubMed,10.1038/s41598-019-52444-7,Sci Rep. 2019 Nov 4;9(1):15884,Kar-Chun.Tan@curtin.edu.au,PnPf2 was required for full hyphal proliferation during host infection.,D A B Jones 2019,2019,1 gene,Jones-2019-A specific fungal transcription fac,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14942,PHI:9607,UniProt,I1S3D7,GenBank,EYB22994,,,CS3005,FgCWM1 (FG05_11315),,,,,,,5518,Fusarium graminearum,,DAOM 180378,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,inflorescence,cell wall mannoprotein,,,,reduced virulence,,,,,,,,wild type,,no,salicylic acid,salicylic acid: CHEBI:16914,,,,,gene deletion: full; gene complementation,,,YVS,31671876,PubMed,10.3390/toxins11110628,Toxins (Basel). 2019 Oct 29;11(11),ymwei@sicau.edu.cn,"Disruption of FgCWM1 reduced mannose and protein accumulation in the fungal cell wall, especially under SA treatment, and resulted in defective fungal cell walls, leading to increased fungal sensitivity to SA.",Y Z Zhang 2019,2019,1 gene,Zhang-2019-Fusarium graminearum FgCWM1 Encodes,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14943,PHI:9608,UniProt,Q882Z2,GenBank,AAO55987,,,DC3000,PscA (PSPTO_2480),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31575767,PubMed,10.1128/mBio.01868-19,MBio. 2019 Oct 1;10(5),emilia.lopez@upm.es,Infection assays with the wild-type strain showed that the presence of saturating concentrations of D-Asp also reduced bacterial virulence.,J P Cerna-Vargas 2019,2019,1 gene,Cerna-Vargas-2019-Chemoperception of Specific,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14944,PHI:9609,UniProt,I1RMN3,GenBank,CEF87472,,,PH-1,FgSec22 (FGSG_05226),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,soluble N-ethylmaleimide-sensitive factor attachment protein receptor,,,deoxynivalenol (DON) biosynthesis,reduced virulence,,,,,,reduced; aberrant,wild type,reduced; aberrant,reduced,no,KCl; NaCl; sorbitol; sodium dodecyl sulfate; calcofluor white; Congo red; H2O2,KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; sodium dodecyl sulfate: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31667538,PubMed,10.1007/s00294-019-01037-y,Curr Genet. 2019 Oct 30,lgd@fafu.edu.cn,"FgSec22 in F. graminearum was indispensable for normal conidiation, conidial morphology and pathogenesis.",M Adnan 2019,2019,1 gene,Adnan-2019-R-SNARE FgSec22 is essential for gr,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14945,PHI:9610,UniProt,K9G1V0,GenBank,EKV15950,,,PHI26,chsII (PDIG_23050),,,,,,,36651,Penicillium digitatum,,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,chitin synthase B,,,chitin biosynthesis,unaffected pathogenicity,,,,,,reduced; aberrant,,wild type,,no,sorbitol; NaCl; calcofluor white; sodium dodecyl sulfate; H2O2; nikkomycin Z,sorbitol: CHEBI:17924; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; H2O2: CHEBI:16240; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,31681248,PubMed,10.3389/fmicb.2019.02400,Front Microbiol. 2019 Oct 18;10:2400,mgandia@iata.csic.es,Deletion of ChsII did not produce significant changes in the morphology or virulence of the fungus but affected its conidia formation process.,M Gandia 2019,2019,3 genes,Gandia-2019-The Myosin Motor Domain-Containing,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14946,PHI:9611,UniProt,K9FIR4,GenBank,EKV08102,,,PHI26,chsV (PDIG_69930),,,,,,,36651,Penicillium digitatum,,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,chitin synthase ChsE,,,chitin biosynthesis,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,sorbitol; NaCl; calcofluor white; sodium dodecyl sulfate; H2O2; nikkomycin Z,sorbitol: CHEBI:17924; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; H2O2: CHEBI:16240; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,31681248,PubMed,10.3389/fmicb.2019.02400,Front Microbiol. 2019 Oct 18;10:2400,mgandia@iata.csic.es,"Mutants in MMD-Chs from division II compromised growth, morphology, and virulence of the fungus, and influenced the sensitivity to antifungal proteins.",M Gandia 2019,2019,3 genes,Gandia-2019-The Myosin Motor Domain-Containing,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14947,PHI:9612,UniProt,K9G4B8,GenBank,EKV08101,,,PHI26,chsVII (PDIG_69920),,,,,,,36651,Penicillium digitatum,,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navelina,,,fruit,"chitin synthase, putative",,,chitin biosynthesis,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,sorbitol; NaCl; calcofluor white; sodium dodecyl sulfate; H2O2; nikkomycin Z,sorbitol: CHEBI:17924; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; H2O2: CHEBI:16240; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,31681248,PubMed,10.3389/fmicb.2019.02400,Front Microbiol. 2019 Oct 18;10:2400,mgandia@iata.csic.es,"Mutants in MMD-Chs from division II compromised growth, morphology, and virulence of the fungus, and influenced the sensitivity to antifungal proteins.",M Gandia 2019,2019,3 genes,Gandia-2019-The Myosin Motor Domain-Containing,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14948,PHI:9613,UniProt,F9XGF4,GenBank,EGP85550,,,IPO323,ZtvelB (MYCGRDRAFT_86705),chromosome 7,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,velvet complex subunit B,,,,unaffected pathogenicity,,,,,,defective,,aberrant,,no,,,,,,,gene deletion: full,,,YVS,31632366,PubMed,10.3389/fmicb.2019.02210,Front Microbiol. 2019 Oct 1;10:2210,andy.bailey@bristol.ac.uk,The ΔztvelB mutants produced abnormal pycnidia that were impaired in macropycnidiospore production but could still produce viable infectious micropycnidiospores.,A M M Tiley 2019,2019,1 gene,Tiley-2019-The ZtvelB Gene Is Required for Veg,BATCH_097A,2019-11-01,MC,,,,,,,,,,,,,
,,Record 14949,PHI:9614,UniProt,A0A5C2EX03,GenBank,QEO97331,,,GX01,XOCgx_2341,,,,,,PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14950,PHI:9615,UniProt,A0A5C2ESG4,GenBank,QEO97332,,,GX01,XOCgx_2342,,,,,,PHI:9614; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14951,PHI:9616,UniProt,A0A5C2ETU4,GenBank,QEO97333,,,GX01,hcp1 (XOCgx_2343),,,,,,PHI:9614; PHI:9615; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14952,PHI:9617,UniProt,A0A5C2ESE0,GenBank,QEO97334,,,GX01,XOCgx_2344,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9618; PHI:9619; PHI:9620; PHI:9621,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14953,PHI:9618,UniProt,A0A5C2ERP3,GenBank,QEO97335,,,GX01,XOCgx_2345,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9619; PHI:9620; PHI:9621,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14954,PHI:9619,UniProt,A0A5C2ETJ9,GenBank,QEO97336,,,GX01,XOCgx_2346,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9620; PHI:9621,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14955,PHI:9620,UniProt,A0A5C2F1E1,GenBank,QEO97337,,,GX01,XOCgx_2347,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9621,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14956,PHI:9621,UniProt,A0A5C2ESP6,GenBank,QEO97338,,,GX01,XOCgx_2348,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,chaperone,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14957,PHI:9622,UniProt,A0A5C2EW12,GenBank,QEO98572,,,GX01,XOCgx_3583,,,,,,PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,protease associated ATPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14958,PHI:9623,UniProt,A0A5C2EX05,GenBank,QEO98573,,,GX01,XOCgx_3584,,,,,,PHI:9622; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14959,PHI:9624,UniProt,A0A5C2EW38,GenBank,QEO98574,,,GX01,XOCgx_3585,,,,,,PHI:9622; PHI:9623; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14960,PHI:9625,UniProt,A0A5C2EVF3,GenBank,QEO98575,,,GX01,XOCgx_3586,,,,,,PHI:9622; PHI:9623; PHI:9624; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14961,PHI:9626,UniProt,A0A5C2EXK8,GenBank,QEO98576,,,GX01,XOCgx_3587,,,,,,PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14962,PHI:9627,UniProt,A0A0C5UMV1,GenBank,QEO98577,,,GX01,hcp2 (XOCgx_3588),,,,,,PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,"type VI secretion system effector, Hcp family protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14963,PHI:9628,UniProt,A0A0C5V2D4,GenBank,QEO98578,,,GX01,XOCgx_3589,,,,,,PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14964,PHI:9614,UniProt,A0A5C2EX03,GenBank,QEO97331,,,GX01,XOCgx_2341,,,,,,PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14965,PHI:9615,UniProt,A0A5C2ESG4,GenBank,QEO97332,,,GX01,XOCgx_2342,,,,,,PHI:9614; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14966,PHI:9616,UniProt,A0A5C2ETU4,GenBank,QEO97333,,,GX01,hcp1 (XOCgx_2343),,,,,,PHI:9614; PHI:9615; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14967,PHI:9617,UniProt,A0A5C2ESE0,GenBank,QEO97334,,,GX01,XOCgx_2344,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14968,PHI:9618,UniProt,A0A5C2ERP3,GenBank,QEO97335,,,GX01,XOCgx_2345,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14969,PHI:9619,UniProt,A0A5C2ETJ9,GenBank,QEO97336,,,GX01,XOCgx_2346,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14970,PHI:9620,UniProt,A0A5C2F1E1,GenBank,QEO97337,,,GX01,XOCgx_2347,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14971,PHI:9621,UniProt,A0A5C2ESP6,GenBank,QEO97338,,,GX01,XOCgx_2348,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,chaperone,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14972,PHI:9622,UniProt,A0A5C2EW12,GenBank,QEO98572,,,GX01,XOCgx_3583,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,protease associated ATPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14973,PHI:9623,UniProt,A0A5C2EX05,GenBank,QEO98573,,,GX01,XOCgx_3584,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9624; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14974,PHI:9624,UniProt,A0A5C2EW38,GenBank,QEO98574,,,GX01,XOCgx_3585,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9625; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14975,PHI:9625,UniProt,A0A5C2EVF3,GenBank,QEO98575,,,GX01,XOCgx_3586,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9626; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14976,PHI:9626,UniProt,A0A5C2EXK8,GenBank,QEO98576,,,GX01,XOCgx_3587,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9627; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14977,PHI:9627,UniProt,A0A0C5UMV1,GenBank,QEO98577,,,GX01,hcp2 (XOCgx_3588),,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9628,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,"type VI secretion system effector, Hcp family protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14978,PHI:9628,UniProt,A0A0C5V2D4,GenBank,QEO98578,,,GX01,XOCgx_3589,,,,,,PHI:9614; PHI:9615; PHI:9616; PHI:9617; PHI:9618; PHI:9619; PHI:9620; PHI:9621; PHI:9622; PHI:9623; PHI:9624; PHI:9625; PHI:9626; PHI:9627,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: cluster,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14979,PHI:9616,UniProt,A0A5C2ETU4,GenBank,QEO97333,,,GX01,hcp1 (XOCgx_2343),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system secreted protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14980,PHI:9627,UniProt,A0A0C5UMV1,GenBank,QEO98577,,,GX01,hcp2 (XOCgx_3588),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,"type VI secretion system effector, Hcp family protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14981,PHI:9616,UniProt,A0A5C2ETU4,GenBank,QEO97333,,,GX01,hcp1 (XOCgx_2343),,,,,,PHI:9627,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,type VI secretion system secreted protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14982,PHI:9627,UniProt,A0A0C5UMV1,GenBank,QEO98577,,,GX01,hcp2 (XOCgx_3588),,,,,,PHI:9616,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,"type VI secretion system effector, Hcp family protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31676435,PubMed,10.1016/j.resmic.2019.10.004,Res Microbiol. 2019 Oct 29,jltang@gxu.edu.cn,"Mutational assays demonstrated that T6SS1 and T6SS2 are not required for the virulence of Xoc GX01 on rice, nevertheless, T6SS2, but not T6SS1, played an important role in bacterial killing.",P C Zhu 2019,2019,15 genes,Zhu-2019-Type VI secretion system is not requi,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14983,PHI:9629,UniProt,F3HS45,GenBank,EGH62165,,,ES4326,PMA4326_25462,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,3-phosphoglyceratede hydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14984,PHI:9630,UniProt,F3HE21,GenBank,EGH57574,,,ES4326,PMA4326_01907,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,D-amino acid dehydrogenase small subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14985,PHI:9631,UniProt,F3HPJ8,GenBank,EGH61268,,,ES4326,PMA4326_20937,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,N-acetyl-gamma-glutamyl-phosphate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14986,PHI:9632,UniProt,F3HE78,GenBank,EGH57628,,,ES4326,PMA4326_02177,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,tryptophan synthase subunit alpha,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14987,PHI:9633,UniProt,F3HN57,GenBank,EGH60808,,,ES4326,PMA4326_18563,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,N-ethylammeline chlorohydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14988,PHI:9634,UniProt,F3HFP1,GenBank,EGH58154,,,ES4326,PMA4326_04881,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,taurine catabolism dioxygenase TauD,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14989,PHI:9635,UniProt,F3HTI7,GenBank,EGH62657,,,ES4326,PMA4326_27962,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,error-prone DNA polymerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14990,PHI:9636,UniProt,F3HQH9,GenBank,EGH61599,,,ES4326,PMA4326_22604,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,helicase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14991,PHI:9637,UniProt,F3HPI6,GenBank,EGH61256,,,ES4326,PMA4326_20877,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,helicase UvrD,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14992,PHI:9638,UniProt,F3HUM4,GenBank,EGH63044,,,ES4326,PMA4326_29937,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,integrase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14993,PHI:9639,UniProt,F3HUN9,GenBank,EGH63059,,,ES4326,PMA4326_30012,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,mobilization protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14994,PHI:9640,UniProt,F3HNW0,GenBank,EGH61030,,,ES4326,PMA4326_19710,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,N-methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14995,PHI:9641,UniProt,F3HM84,GenBank,EGH60454,,,ES4326,PMA4326_16681,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,ArsR transcriptional factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14996,PHI:9642,UniProt,F3HSX2,GenBank,EGH62442,,,ES4326,PMA4326_26857,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,Fis family transcriptional factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14997,PHI:9643,UniProt,F3HEA0,GenBank,EGH57650,,,ES4326,PMA4326_02287,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,HexR transcriptional factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14998,PHI:9644,UniProt,F3HHI8,GenBank,EGH58801,,,ES4326,PMA4326_08221,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,LysR family transcriptional factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 14999,PHI:9645,UniProt,F3HQ15,GenBank,EGH61435,,,ES4326,PMA4326_21784,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,AraC family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15000,PHI:9646,UniProt,F3HU22,GenBank,EGH62842,,,ES4326,PMA4326_28915,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,DNA topoisomerase III,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15001,PHI:9647,UniProt,F3HU30,GenBank,EGH62850,,,ES4326,PMA4326_28955,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,relaxase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15002,PHI:9648,UniProt,F3HSF7,GenBank,EGH62277,,,ES4326,PMA4326_26032,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,D-tyrosyl-tRNA(Tyr) deacylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15003,PHI:9649,UniProt,F3HQN7,GenBank,EGH61657,,,ES4326,PMA4326_22906,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,phosphoribosylaminoimidazole carboxylase ATPase subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15004,PHI:9650,UniProt,F3HG40,GenBank,EGH58305,,,ES4326,PMA4326_05636,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,polynucleotide phosphorylase/polyadenylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15005,PHI:9651,UniProt,F3HFA0,GenBank,EGH58013,,,ES4326,PMA4326_04134,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15006,PHI:9652,UniProt,F3HNX1,GenBank,EGH61041.1,,,ES4326,PMA4326_19765,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,phosphoribosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15007,PHI:9653,UniProt,F3HPD8,GenBank,EGH61208,,,ES4326,PMA4326_20637,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,acetyltransferase family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15008,PHI:9654,UniProt,F3HMP2,GenBank,EGH60612,,,ES4326,PMA4326_17521,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,lipid kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15009,PHI:9655,UniProt,F3HIN0,GenBank,EGH59200,,,ES4326,PMA4326_10330,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,acyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15010,PHI:9656,UniProt,F3HSF9,GenBank,EGH62279,,,ES4326,PMA4326_26042,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,glycogen phosphorylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15011,PHI:9657,UniProt,F3HI87,GenBank,EGH59057,,,ES4326,PMA4326_09615,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,glycerol kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15012,PHI:9658,UniProt,F3HP60,GenBank,EGH61130,,,ES4326,PMA4326_20235,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,malate:quinone oxidoreductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15013,PHI:9659,UniProt,F3HDI9,GenBank,EGH57402,,,ES4326,PMA4326_01045,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,polyphosphate kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15014,PHI:9660,UniProt,F3HJT6,GenBank,EGH59606,,,ES4326,PMA4326_12408,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,RND transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15015,PHI:9661,UniProt,F3HSJ9,GenBank,EGH62319,,,ES4326,PMA4326_26242,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,sulfonate ABC transporter substrate-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15016,PHI:9662,UniProt,F3HLK2,GenBank,EGH60222.1,,,ES4326,PMA4326_15504,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,D-alanyl-D-alanine carboxypeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15017,PHI:9663,UniProt,F3HQR8,GenBank,EGH61688,,,ES4326,PMA4326_23061,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15018,PHI:9664,UniProt,F3HMA2,GenBank,EGH60472,,,ES4326,PMA4326_16771,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15019,PHI:9665,UniProt,F3HFG0,GenBank,EGH58079,,,ES4326,PMA4326_04474,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,HDOD domain protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15020,PHI:9666,UniProt,F3HEI6,GenBank,EGH57749,,,ES4326,PMA4326_02782,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,type III secretion protein HrcQb,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15021,PHI:9667,UniProt,F3HPK7,GenBank,EGH61277,,,ES4326,PMA4326_20982,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,lipoate-protein ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15022,PHI:9668,UniProt,F3HM07,GenBank,EGH60377.1,,,ES4326,PMA4326_16286,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,nitrate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15023,PHI:9669,UniProt,F3HD58,GenBank,EGH57271,,,ES4326,PMA4326_00370,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,16S rRNA methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15024,PHI:9670,UniProt,F3HET5,GenBank,EGH57848.1,,,ES4326,PMA4326_03299,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,heme oxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15025,PHI:9671,UniProt,F3HNQ0,GenBank,EGH60970,,,ES4326,PMA4326_19408,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15026,PHI:9672,UniProt,F3HIW4,GenBank,EGH59284,,,ES4326,PMA4326_10750,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,YD repeat-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15027,PHI:9673,UniProt,F3HUW0,GenBank,EGH63130,,,ES4326,PMA4326_30377,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15028,PHI:9674,UniProt,F3HT34,GenBank,EGH62504,,,ES4326,PMA4326_27167,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15029,PHI:9675,UniProt,F3HU84,GenBank,EGH62904,,,ES4326,PMA4326_29225,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15030,PHI:9676,UniProt,F3HTA8,GenBank,EGH62578.1,,,ES4326,PMA4326_27567,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15031,PHI:9677,,no data found,GenBank,EGH58845,,,ES4326,PMA4326_08475,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15032,PHI:9678,UniProt,F3HN98,GenBank,EGH60818,,,ES4326,PMA4326_18613,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Kinkei 201,,,seedling,rhodanese-like domain protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15033,PHI:9632,UniProt,F3HE78,GenBank,EGH57628,,,ES4326,PMA4326_02177,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,tryptophan synthase subunit alpha,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15034,PHI:9629,UniProt,F3HS45,GenBank,EGH62165,,,ES4326,PMA4326_25462,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,3-phosphoglyceratede hydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15035,PHI:9631,UniProt,F3HPJ8,GenBank,EGH61268,,,ES4326,PMA4326_20937,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,N-acetyl-gamma-glutamyl-phosphate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15036,PHI:9630,UniProt,F3HE21,GenBank,EGH57574,,,ES4326,PMA4326_01907,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,D-amino acid dehydrogenase small subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15037,PHI:9643,UniProt,F3HEA0,GenBank,EGH57650,,,ES4326,PMA4326_02287,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,HexR transcriptional factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15038,PHI:9641,UniProt,F3HM84,GenBank,EGH60454,,,ES4326,PMA4326_16681,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,ArsR transcriptional factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15039,PHI:9644,UniProt,F3HHI8,GenBank,EGH58801,,,ES4326,PMA4326_08221,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,LysR family transcriptional factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15040,PHI:9642,UniProt,F3HSX2,GenBank,EGH62442,,,ES4326,PMA4326_26857,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,Fis family transcriptional factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15041,PHI:9649,UniProt,F3HQN7,GenBank,EGH61657,,,ES4326,PMA4326_22906,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,phosphoribosylaminoimidazole carboxylase ATPase subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15042,PHI:9650,UniProt,F3HG40,GenBank,EGH58305,,,ES4326,PMA4326_05636,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,polynucleotide phosphorylase/polyadenylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15043,PHI:9648,UniProt,F3HSF7,GenBank,EGH62277,,,ES4326,PMA4326_26032,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,D-tyrosyl-tRNA(Tyr) deacylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15044,PHI:9646,UniProt,F3HU22,GenBank,EGH62842,,,ES4326,PMA4326_28915,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,DNA topoisomerase III,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15045,PHI:9635,UniProt,F3HTI7,GenBank,EGH62657,,,ES4326,PMA4326_27962,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,error-prone DNA polymerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15046,PHI:9662,UniProt,F3HLK2,GenBank,EGH60222.1,,,ES4326,PMA4326_15504,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,D-alanyl-D-alanine carboxypeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15047,PHI:9663,UniProt,F3HQR8,GenBank,EGH61688,,,ES4326,PMA4326_23061,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15048,PHI:9658,UniProt,F3HP60,GenBank,EGH61130,,,ES4326,PMA4326_20235,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,malate:quinone oxidoreductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15049,PHI:9659,UniProt,F3HDI9,GenBank,EGH57402,,,ES4326,PMA4326_01045,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,polyphosphate kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15050,PHI:9660,UniProt,F3HJT6,GenBank,EGH59606,,,ES4326,PMA4326_12408,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,RND transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15051,PHI:9661,UniProt,F3HSJ9,GenBank,EGH62319,,,ES4326,PMA4326_26242,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,sulfonate ABC transporter substrate-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15052,PHI:9653,UniProt,F3HPD8,GenBank,EGH61208,,,ES4326,PMA4326_20637,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,acetyltransferase family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15053,PHI:9654,UniProt,F3HMP2,GenBank,EGH60612,,,ES4326,PMA4326_17521,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,lipid kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15054,PHI:9666,UniProt,F3HEI6,GenBank,EGH57749,,,ES4326,PMA4326_02782,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,type III secretion protein HrcQb,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15055,PHI:9668,UniProt,F3HM07,GenBank,EGH60377.1,,,ES4326,PMA4326_16286,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,nitrate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15056,PHI:9669,UniProt,F3HD58,GenBank,EGH57271,,,ES4326,PMA4326_00370,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,16S rRNA methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15057,PHI:9667,UniProt,F3HPK7,GenBank,EGH61277,,,ES4326,PMA4326_20982,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,lipoate-protein ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15058,PHI:9656,UniProt,F3HSF9,GenBank,EGH62279,,,ES4326,PMA4326_26042,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,glycogen phosphorylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15059,PHI:9664,UniProt,F3HMA2,GenBank,EGH60472,,,ES4326,PMA4326_16771,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15060,PHI:9647,UniProt,F3HU30,GenBank,EGH62850,,,ES4326,PMA4326_28955,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,relaxase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15061,PHI:9671,UniProt,F3HNQ0,GenBank,EGH60970,,,ES4326,PMA4326_19408,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15062,PHI:9672,UniProt,F3HIW4,EMBL,EGH59284,,,ES4326,PMA4326_10750,,,,,,,86840,Pseudomonas cannabina,757414,pv. alisalensis strain KB211,blight,monocots,38783,Avena strigosa (related: black oat),cv. Hayoat,,,seedling,YD repeat-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31579596,PubMed,10.7717/peerj.7698,PeerJ. 2019 Sep 20;7:e7698,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Pcal optimized its virulence factors for pathogenicity on different host plants.,N Sakata 2019,2019,50 genes,Sakata-2019-Transposon mutagenesis reveals Pse,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15063,PHI:9679,UniProt,Q07730,EMBL,AAA34338,,,SC5314,ECE1,,,,,,,5476,Candida albicans,,M1477,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver,extent of cell elongation protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31606552,PubMed,10.1016/j.jhep.2019.09.029,J Hepatol. 2019 Oct 10. pii: S0168-8278(19)30599-9,beschnabl@ucsd.edu,Candidalysin is associated with progression of ethanol-induced liver disease.,H Chu 2019,2019,1 gene,Chu-2019-The Candida albicans exotoxin Candida,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15064,PHI:9679,UniProt,Q07730,EMBL,AAA34338,,,SC5314,ECE1,,ECE1Δ184–279,,,,,5476,Candida albicans,,M1477,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver,extent of cell elongation protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31606552,PubMed,10.1016/j.jhep.2019.09.029,J Hepatol. 2019 Oct 10. pii: S0168-8278(19)30599-9,beschnabl@ucsd.edu,Candidalysin is associated with progression of ethanol-induced liver disease.,H Chu 2019,2019,1 gene,Chu-2019-The Candida albicans exotoxin Candida,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15065,PHI:9679,UniProt,Q07730,EMBL,AAA34338,,,SC5314,ECE1,,,,,,,5476,Candida albicans,,M1477,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (Clec7a<-/->),,,bone marrow,extent of cell elongation protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31606552,PubMed,10.1016/j.jhep.2019.09.029,J Hepatol. 2019 Oct 10. pii: S0168-8278(19)30599-9,beschnabl@ucsd.edu,Candidalysin is associated with progression of ethanol-induced liver disease.,H Chu 2019,2019,1 gene,Chu-2019-The Candida albicans exotoxin Candida,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15066,PHI:9679,UniProt,Q07730,EMBL,AAA34338,,,SC5314,ECE1,,,,,,,5476,Candida albicans,,M1477,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestinal epithelial cell,extent of cell elongation protein 1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31606552,PubMed,10.1016/j.jhep.2019.09.029,J Hepatol. 2019 Oct 10. pii: S0168-8278(19)30599-9,beschnabl@ucsd.edu,Candidalysin is associated with progression of ethanol-induced liver disease.,H Chu 2019,2019,1 gene,Chu-2019-The Candida albicans exotoxin Candida,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15067,PHI:9680,UniProt,N4XA40,GenBank,ENI02037,,,ATCC 48331,cdc3,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,septin,,,,unaffected pathogenicity,,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31698077,PubMed,10.1016/j.fgb.2019.103291,Fungal Genet Biol. 2019 Nov 4;135:103291,zhangxianghui1982@126.com,Reduced virulence was demonstrated to be correlated with lower germination rate of cdc10 mutant conidia.,X Zhang 2019,2019,5 genes,Zhang-2019-Septins are required for reproducti,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15068,PHI:9681,UniProt,N4X719,GenBank,ENI01022,,,ATCC 48331,cdc10,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,septin,,,,reduced virulence,,,,,,,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31698077,PubMed,10.1016/j.fgb.2019.103291,Fungal Genet Biol. 2019 Nov 4;135:103291,zhangxianghui1982@126.com,Reduced virulence was demonstrated to be correlated with lower germination rate of cdc10 mutant conidia.,X Zhang 2019,2019,5 genes,Zhang-2019-Septins are required for reproducti,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15069,PHI:9682,UniProt,N4WKL9,GenBank,ENI00909,,,ATCC 48331,cdc11,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,septin,,,,unaffected pathogenicity,,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31698077,PubMed,10.1016/j.fgb.2019.103291,Fungal Genet Biol. 2019 Nov 4;135:103291,zhangxianghui1982@126.com,Reduced virulence was demonstrated to be correlated with lower germination rate of cdc10 mutant conidia.,X Zhang 2019,2019,5 genes,Zhang-2019-Septins are required for reproducti,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15070,PHI:9683,UniProt,N4XRR6,GenBank,ENI07852,,,ATCC 48331,cdc12,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,septin,,,,unaffected pathogenicity,,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31698077,PubMed,10.1016/j.fgb.2019.103291,Fungal Genet Biol. 2019 Nov 4;135:103291,zhangxianghui1982@126.com,Reduced virulence was demonstrated to be correlated with lower germination rate of cdc10 mutant conidia.,X Zhang 2019,2019,5 genes,Zhang-2019-Septins are required for reproducti,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15071,PHI:9680,UniProt,N4XA40,GenBank,ENI02037,,,ATCC 48331,cdc3,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,septin,,,,reduced virulence,,,,,,,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31698077,PubMed,10.1016/j.fgb.2019.103291,Fungal Genet Biol. 2019 Nov 4;135:103291,zhangxianghui1982@126.com,Reduced virulence was demonstrated to be correlated with lower germination rate of cdc10 mutant conidia.,X Zhang 2019,2019,5 genes,Zhang-2019-Septins are required for reproducti,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15072,PHI:9681,UniProt,N4X719,GenBank,ENI01022,,,ATCC 48331,cdc10,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,septin,,,,reduced virulence,,,,,,,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31698077,PubMed,10.1016/j.fgb.2019.103291,Fungal Genet Biol. 2019 Nov 4;135:103291,zhangxianghui1982@126.com,Reduced virulence was demonstrated to be correlated with lower germination rate of cdc10 mutant conidia.,X Zhang 2019,2019,5 genes,Zhang-2019-Septins are required for reproducti,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15073,PHI:9680,UniProt,N4XA40,GenBank,ENI02037,,,ATCC 48331,cdc3,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,septin,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31698077,PubMed,10.1016/j.fgb.2019.103291,Fungal Genet Biol. 2019 Nov 4;135:103291,zhangxianghui1982@126.com,Reduced virulence was demonstrated to be correlated with lower germination rate of cdc10 mutant conidia.,X Zhang 2019,2019,5 genes,Zhang-2019-Septins are required for reproducti,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15074,PHI:9682,UniProt,N4WKL9,GenBank,ENI00909,,,ATCC 48331,cdc11,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,septin,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31698077,PubMed,10.1016/j.fgb.2019.103291,Fungal Genet Biol. 2019 Nov 4;135:103291,zhangxianghui1982@126.com,Reduced virulence was demonstrated to be correlated with lower germination rate of cdc10 mutant conidia.,X Zhang 2019,2019,5 genes,Zhang-2019-Septins are required for reproducti,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15075,PHI:9684,UniProt,N4XXT4,GenBank,ENI09997,,,ATCC 48331,cdc100,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-T,,,leaf,septin,,,,unaffected pathogenicity,,,,,,,reduced,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31698077,PubMed,10.1016/j.fgb.2019.103291,Fungal Genet Biol. 2019 Nov 4;135:103291,zhangxianghui1982@126.com,Reduced virulence was demonstrated to be correlated with lower germination rate of cdc10 mutant conidia.,X Zhang 2019,2019,5 genes,Zhang-2019-Septins are required for reproducti,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15076,PHI:9681,UniProt,N4X719,GenBank,ENI01022,,,ATCC 48331,cdc10,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. W64A-N,,,leaf,septin,,,,unaffected pathogenicity,,,,,,,reduced,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31698077,PubMed,10.1016/j.fgb.2019.103291,Fungal Genet Biol. 2019 Nov 4;135:103291,zhangxianghui1982@126.com,Reduced virulence was demonstrated to be correlated with lower germination rate of cdc10 mutant conidia.,X Zhang 2019,2019,5 genes,Zhang-2019-Septins are required for reproducti,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15077,PHI:9685,UniProt,Q880X6,GenBank,AAO56514,,,DC3000,gacA,,Tn5::gacA,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,DNA-binding response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,31600319,PubMed,10.1371/journal.pone.0223637,PLoS One. 2019 Oct 10;14(10):e0223637,anderje2@oregonstate.edu,Defects in anmK and uvrC are together sufficient to account for the decreased virulence of AC811.,M R O'Malley 2019,2019,4 genes,O'Malley-2019-Re-evaluation of a Tn5__gacA mut,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15078,PHI:9686,UniProt,Q889Z1,GenBank,AAO54148,,,DC3000,anmK (PSPTO_0606),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,"1,6-anhydromuramic acid kinase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31600319,PubMed,10.1371/journal.pone.0223637,PLoS One. 2019 Oct 10;14(10):e0223637,anderje2@oregonstate.edu,Defects in anmK and uvrC are together sufficient to account for the decreased virulence of AC811.,M R O'Malley 2019,2019,4 genes,O'Malley-2019-Re-evaluation of a Tn5__gacA mut,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15079,PHI:9685,UniProt,Q880X6,GenBank,AAO56514,,,DC3000,gacA,,ΔgacA anmK+,,,,PHI:9687,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,DNA-binding response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31600319,PubMed,10.1371/journal.pone.0223637,PLoS One. 2019 Oct 10;14(10):e0223637,anderje2@oregonstate.edu,Defects in anmK and uvrC are together sufficient to account for the decreased virulence of AC811.,M R O'Malley 2019,2019,4 genes,O'Malley-2019-Re-evaluation of a Tn5__gacA mut,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15080,PHI:9687,UniProt,Q880X7,GenBank,AAO56513,,,DC3000,uvrC,,ΔgacA anmK+,,,,PHI:9685,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,"excinuclease ABC, C subunit",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31600319,PubMed,10.1371/journal.pone.0223637,PLoS One. 2019 Oct 10;14(10):e0223637,anderje2@oregonstate.edu,Defects in anmK and uvrC are together sufficient to account for the decreased virulence of AC811.,M R O'Malley 2019,2019,4 genes,O'Malley-2019-Re-evaluation of a Tn5__gacA mut,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15081,PHI:9688,UniProt,Q888F9,GenBank,AAO54596,,,DC3000,PSPTO_1067,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,"glycosyl transferase, group 2 family protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31600319,PubMed,10.1371/journal.pone.0223637,PLoS One. 2019 Oct 10;14(10):e0223637,anderje2@oregonstate.edu,Defects in anmK and uvrC are together sufficient to account for the decreased virulence of AC811.,M R O'Malley 2019,2019,4 genes,O'Malley-2019-Re-evaluation of a Tn5__gacA mut,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15082,PHI:9685,UniProt,Q880X6,GenBank,AAO56514,,,DC3000,gacA,,ΔgacA anmK+,,,,PHI:9686,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,DNA-binding response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31600319,PubMed,10.1371/journal.pone.0223637,PLoS One. 2019 Oct 10;14(10):e0223637,anderje2@oregonstate.edu,Defects in anmK and uvrC are together sufficient to account for the decreased virulence of AC811.,M R O'Malley 2019,2019,4 genes,O'Malley-2019-Re-evaluation of a Tn5__gacA mut,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15083,PHI:9686,UniProt,Q889Z1,GenBank,AAO54148,,,DC3000,anmK (PSPTO_0606),,ΔgacA anmK+,,,,PHI:9685,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,"1,6-anhydromuramic acid kinase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31600319,PubMed,10.1371/journal.pone.0223637,PLoS One. 2019 Oct 10;14(10):e0223637,anderje2@oregonstate.edu,Defects in anmK and uvrC are together sufficient to account for the decreased virulence of AC811.,M R O'Malley 2019,2019,4 genes,O'Malley-2019-Re-evaluation of a Tn5__gacA mut,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15084,PHI:9689,UniProt,A0A3M4WG27,GenBank,RMR62990,,,ICMP 6917,wbpL,,,,,,,36746,Pseudomonas cichorii,,ATCC 10857,bacterial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,glycosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31559681,PubMed,10.1111/mpp.12864,Mol Plant Pathol. 2019 Nov;20(11):1535-1549,alexander.kutschera@tum.de,WbpL knockout diminished swarming motility,A Kutschera 2019,2019,2 genes,Kutschera-2019-Loss of wbpL disrupts O-polysac,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15085,PHI:9690,UniProt,A0A3M3PL36,GenBank,RMN72646,,,1188_1,wbpL,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial infection,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,glycosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31559681,PubMed,10.1111/mpp.12864,Mol Plant Pathol. 2019 Nov;20(11):1535-1549,alexander.kutschera@tum.de,WbpL knockout diminished swarming motility,A Kutschera 2019,2019,2 genes,Kutschera-2019-Loss of wbpL disrupts O-polysac,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15086,PHI:9691,,no data found,,,,,,Pbp1,,,,Mkt1,UniProt: J9VT48; GenBank: AFR97408,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,poly(A)-binding protein-binding protein,,,,reduced virulence,yes,,,,,,reduced,,,no,,,,,,,gene deletion: full,,,YVS,31681631,PubMed,10.3389/fcimb.2019.00355,Front Cell Infect Microbiol. 2019 Oct 17;9:355,phsoo97@knu.ac.kr,Pbp1 deletion mutants and mkt1 deletion mutants exhibited defective dikaryotic hyphal production and reduced pheromone gene (MFa1) expression during mating.,Y E Son 2019,2019,3 genes,Son-2019-Pbp1-Interacting Protein Mkt1 Regulat,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15087,PHI:9692,UniProt,J9VT48,GenBank,AFR97408,,,H99,Mkt1 (CNAG_04808),chromosome 10,,,Pbp1,UniProt: P53297; GenBank: AAB94294,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,XPG N-terminal domain-containing protein,,,,reduced virulence,yes,,,,,,reduced,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31681631,PubMed,10.3389/fcimb.2019.00355,Front Cell Infect Microbiol. 2019 Oct 17;9:355,phsoo97@knu.ac.kr,Pbp1 deletion mutants and mkt1 deletion mutants exhibited defective dikaryotic hyphal production and reduced pheromone gene (MFa1) expression during mating.,Y E Son 2019,2019,3 genes,Son-2019-Pbp1-Interacting Protein Mkt1 Regulat,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15088,PHI:9693,UniProt,Q9Y879,GenBank,AAD44336,,,JEC21,cna1,,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,serine/threonine-protein phosphatase,,,,reduced virulence,yes,,,,,,reduced,,,no,,,,,,,gene deletion: full,,,YVS,31681631,PubMed,10.3389/fcimb.2019.00355,Front Cell Infect Microbiol. 2019 Oct 17;9:355,phsoo97@knu.ac.kr,Pbp1 deletion mutants and mkt1 deletion mutants exhibited defective dikaryotic hyphal production and reduced pheromone gene (MFa1) expression during mating.,Y E Son 2019,2019,3 genes,Son-2019-Pbp1-Interacting Protein Mkt1 Regulat,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15089,PHI:9694,UniProt,Q7ALE2,GenBank,CAD18017,,,GMI1000,hrpJ,,,,hpaP,UniProt: P35651; GenBank: CAB58249,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,putative component of the T3SS apparatus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31567040,PubMed,10.1094/MPMI-05-19-0139-R,Mol Plant Microbe Interact. 2019 Sep 30,fabienne.vailleau@inra.fr,"The hrpJ mutant did not elicit any HR, unlike the wild-type strain.",F Lonjon 2019,2019,1 gene,"Lonjon-2019-HpaP sequesters HrpJ, an essential",BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15090,PHI:9694,UniProt,Q7ALE2,GenBank,CAD18017,,,GMI1000,hrpJ,,,,hpaP,UniProt: P35651; GenBank: CAB58249,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,putative component of the T3SS apparatus,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31567040,PubMed,10.1094/MPMI-05-19-0139-R,Mol Plant Microbe Interact. 2019 Sep 30,fabienne.vailleau@inra.fr,No disease was observed on A. thaliana inoculated with the hrpJ mutant.,F Lonjon 2019,2019,1 gene,"Lonjon-2019-HpaP sequesters HrpJ, an essential",BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15091,PHI:9695,,no data found,,,,,,PstGSRE1,,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,31606466,PubMed,10.1016/j.molp.2019.09.010,Mol Plant. 2019 Oct 10,guojunwgq@nwsuaf.edu.cn,Host-induced gene silencing of PstGSRE1 significantly reduced the virulence of Pst and increased H2O2 accumulation in wheat.,T Qi 2019,2019,1 gene,Qi-2019-Stripe Rust Effector PstGSRE1 Disrupts,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15092,PHI:9696,UniProt,A0A3V8MN56,GenBank,EAA9114050,,,,MgtR,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hydrophobic membrane peptide,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31649255,PubMed,10.1038/s41598-019-51760-2,Sci Rep. 2019 Oct 24;9(1):15253,anne.blanc-potard@umontpellier.fr,"Endogenous overproduction of MgtR reduced Salmonella replication inside macrophages and lowered MgtC protein level, whereas a peptide variant of MgtR (MgtR-S17I), had no effect.",M R Olvera 2019,2019,1 gene,Olvera-2019-Synthetic hydrophobic peptides der,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15093,PHI:9696,UniProt,A0A3V8MN56,GenBank,EAA9114050,,,,MgtR,,MgtR-S17I,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hydrophobic membrane peptide,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant mutant proteins,,,YVS,31649255,PubMed,10.1038/s41598-019-51760-2,Sci Rep. 2019 Oct 24;9(1):15253,anne.blanc-potard@umontpellier.fr,"Endogenous overproduction of MgtR reduced Salmonella replication inside macrophages and lowered MgtC protein level, whereas a peptide variant of MgtR (MgtR-S17I), had no effect.",M R Olvera 2019,2019,1 gene,Olvera-2019-Synthetic hydrophobic peptides der,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15094,PHI:9697,UniProt,A0A454GIY0,GenBank,OSO91949,,,BSK-10,norV,,,,,,,644,Aeromonas hydrophila,,NJ-35,infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,anaerobic nitric oxide reductase flavorubredoxin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31547881,PubMed,10.1186/s13567-019-0683-6,Vet Res. 2019 Sep 23;50(1):67,liuyongjie@njau.edu.cn,"The deletion of norV exhibited markedly decreased cytotoxicity, hemolytic and protease activities under aerobic and anaerobic conditions.",J Liu 2019,2019,1 gene,Liu-2019-Diverse effects of nitric oxide reduc,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15095,PHI:9697,UniProt,A0A454GIY0,GenBank,OSO91949,,,BSK-10,norV,,,,,,,644,Aeromonas hydrophila,,NJ-35,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,anaerobic nitric oxide reductase flavorubredoxin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31547881,PubMed,10.1186/s13567-019-0683-6,Vet Res. 2019 Sep 23;50(1):67,liuyongjie@njau.edu.cn,"The deletion of norV exhibited markedly decreased cytotoxicity, hemolytic and protease activities under aerobic and anaerobic conditions.",J Liu 2019,2019,1 gene,Liu-2019-Diverse effects of nitric oxide reduc,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15096,PHI:9698,UniProt,A0A0B3WJ97,GenBank,AJI51145,,,FTT_1,RelA (FTL_0285),,,,,,,263,Francisella tularensis,,subsp. holarctica strain LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,H2O2; paraquat; pyrogallol,H2O2: CHEBI:16240; paraquat: CHEBI:34905; pyrogallol: CHEBI:16164,,,,,gene deletion: full; gene complementation,,,YVS,31648246,PubMed,10.1371/journal.pone.0224094,PLoS One. 2019 Oct 24;14(10):e0224094,Shekhar_Bakshi@nymc.edu,"The lack of stringent response in relA/spoT gene deletion mutants of F. tularensis made bacteria more susceptible to oxidants, attenuated survival in macrophages, and virulence in mice.",Z Ma 2019,2019,2 genes,Ma-2019-Stringent response governs the oxidati,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15097,PHI:9698,UniProt,A0A0B3WJ97,GenBank,AJI51145,,,FTT_1,RelA (FTL_0285),,,,,,PHI:9699,263,Francisella tularensis,,subsp. holarctica strain LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,H2O2; paraquat; pyrogallol,H2O2: CHEBI:16240; paraquat: CHEBI:34905; pyrogallol: CHEBI:16164,,,,,gene deletion: full; gene complementation,,,YVS,31648246,PubMed,10.1371/journal.pone.0224094,PLoS One. 2019 Oct 24;14(10):e0224094,Shekhar_Bakshi@nymc.edu,"The lack of stringent response in relA/spoT gene deletion mutants of F. tularensis made bacteria more susceptible to oxidants, attenuated survival in macrophages, and virulence in mice.",Z Ma 2019,2019,2 genes,Ma-2019-Stringent response governs the oxidati,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15098,PHI:9699,UniProt,A0A0B3VE08,GenBank,AJI50907,,,FTT_1,SpoT (FTL_1413),,,,,,PHI:9698,263,Francisella tularensis,,subsp. holarctica strain LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,guanosine-3' 5'-bis (diphosphate) 3'-phosphohydrolase/(p)ppGpp synthase,,,,reduced virulence,,,,,,,,,,no,H2O2; paraquat; pyrogallol,H2O2: CHEBI:16240; paraquat: CHEBI:34905; pyrogallol: CHEBI:16164,,,,,gene deletion: full; gene complementation,,,YVS,31648246,PubMed,10.1371/journal.pone.0224094,PLoS One. 2019 Oct 24;14(10):e0224094,Shekhar_Bakshi@nymc.edu,"The lack of stringent response in relA/spoT gene deletion mutants of F. tularensis made bacteria more susceptible to oxidants, attenuated survival in macrophages, and virulence in mice.",Z Ma 2019,2019,2 genes,Ma-2019-Stringent response governs the oxidati,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15099,PHI:9698,UniProt,A0A0B3WJ97,GenBank,AJI51145,,,FTT_1,RelA (FTL_0285),,,,,,,263,Francisella tularensis,,subsp. holarctica strain LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,H2O2; paraquat; pyrogallol,H2O2: CHEBI:16240; paraquat: CHEBI:34905; pyrogallol: CHEBI:16164,,,,,gene deletion: full; gene complementation,,,YVS,31648246,PubMed,10.1371/journal.pone.0224094,PLoS One. 2019 Oct 24;14(10):e0224094,Shekhar_Bakshi@nymc.edu,"The lack of stringent response in relA/spoT gene deletion mutants of F. tularensis made bacteria more susceptible to oxidants, attenuated survival in macrophages, and virulence in mice.",Z Ma 2019,2019,2 genes,Ma-2019-Stringent response governs the oxidati,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15100,PHI:9698,UniProt,A0A0B3WJ97,GenBank,AJI51145,,,FTT_1,RelA (FTL_0285),,,,,,PHI:9699,263,Francisella tularensis,,subsp. holarctica strain LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,H2O2; paraquat; pyrogallol,H2O2: CHEBI:16240; paraquat: CHEBI:34905; pyrogallol: CHEBI:16164,,,,,gene deletion: full; gene complementation,,,YVS,31648246,PubMed,10.1371/journal.pone.0224094,PLoS One. 2019 Oct 24;14(10):e0224094,Shekhar_Bakshi@nymc.edu,"The lack of stringent response in relA/spoT gene deletion mutants of F. tularensis made bacteria more susceptible to oxidants, attenuated survival in macrophages, and virulence in mice.",Z Ma 2019,2019,2 genes,Ma-2019-Stringent response governs the oxidati,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15101,PHI:9699,UniProt,A0A0B3VE08,GenBank,AJI50907,,,FTT_1,SpoT (FTL_1413),,,,,,PHI:9698,263,Francisella tularensis,,subsp. holarctica strain LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,guanosine-3' 5'-bis (diphosphate) 3'-phosphohydrolase/(p)ppGpp synthase,,,,reduced virulence,,,,,,,,,,no,H2O2; paraquat; pyrogallol,H2O2: CHEBI:16240; paraquat: CHEBI:34905; pyrogallol: CHEBI:16164,,,,,gene deletion: full; gene complementation,,,YVS,31648246,PubMed,10.1371/journal.pone.0224094,PLoS One. 2019 Oct 24;14(10):e0224094,Shekhar_Bakshi@nymc.edu,"The lack of stringent response in relA/spoT gene deletion mutants of F. tularensis made bacteria more susceptible to oxidants, attenuated survival in macrophages, and virulence in mice.",Z Ma 2019,2019,2 genes,Ma-2019-Stringent response governs the oxidati,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15102,PHI:9700,UniProt,K3V3D7,GenBank,EKJ79781,,,CS3096,FpDEP1 (FPSE_00061),,,,,,,101028,Fusarium pseudograminearum,,WZ-8A,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Aikang 58,,,coleoptile,component of Rpd3L histone deacetylase complex,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,H2O2; SDS,H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31706014,PubMed,10.1016/j.fgb.2019.103299,Fungal Genet Biol. 2019 Nov 6:103299,shengliding@henau.edu.cn,The ΔFpdep1 mutant presented delayed endocytosis.,Y Zhang 2019,2019,1 gene,"Zhang-2019-FpDep1, a component of Rpd3L histon",BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15103,PHI:9700,UniProt,K3V3D7,GenBank,EKJ79781,,,CS3096,FpDEP1 (FPSE_00061),,,,,,,101028,Fusarium pseudograminearum,,WZ-8A,Fusarium crown rot,monocots,4513,Hordeum vulgare (related: barley),cv. Kenpi-7,,,leaf,component of Rpd3L histone deacetylase complex,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,H2O2; SDS,H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31706014,PubMed,10.1016/j.fgb.2019.103299,Fungal Genet Biol. 2019 Nov 6:103299,shengliding@henau.edu.cn,The ΔFpdep1 mutant presented delayed endocytosis.,Y Zhang 2019,2019,1 gene,"Zhang-2019-FpDep1, a component of Rpd3L histon",BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15104,PHI:9701,UniProt,A0A2T0ANK5,GenBank,PRR70560,,,DSM 5974,lrp,,,,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon; cecum,transcriptionalRegulator,,,,increased virulence (hypervirulence),,,,,,increased,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31681632,PubMed,10.3389/fcimb.2019.00356,Front Cell Infect Microbiol. 2019 Oct 17;9:356,ihsiuhuang@mail.ncku.edu.tw,Significantly decreased cecum weight was observed in the lrp mutant group compared with the wild type group.,K Y Chen 2019,2019,1 gene,Chen-2019-The Transcriptional Regulator Lrp Co,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15105,PHI:9701,UniProt,A0A2T0ANK5,GenBank,PRR70560,,,DSM 5974,lrp,,,,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,transcriptionalRegulator,,,,increased virulence (hypervirulence),,,,,,increased,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31681632,PubMed,10.3389/fcimb.2019.00356,Front Cell Infect Microbiol. 2019 Oct 17;9:356,ihsiuhuang@mail.ncku.edu.tw,R20291 lrp mutants displayed higher cytotoxicity towards both Caco-2 and Vero cells. epithelial colorectal adenocarcinoma cells,K Y Chen 2019,2019,1 gene,Chen-2019-The Transcriptional Regulator Lrp Co,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15106,PHI:9701,UniProt,A0A2T0ANK5,GenBank,PRR70560,,,DSM 5974,lrp,,,,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,transcriptionalRegulator,,,,increased virulence (hypervirulence),,,,,,increased,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31681632,PubMed,10.3389/fcimb.2019.00356,Front Cell Infect Microbiol. 2019 Oct 17;9:356,ihsiuhuang@mail.ncku.edu.tw,R20291 lrp mutants displayed higher cytotoxicity towards both Caco-2 and Vero cells.Kidney epithelial cells,K Y Chen 2019,2019,1 gene,Chen-2019-The Transcriptional Regulator Lrp Co,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15107,PHI:9701,UniProt,A0A2T0ANK5,GenBank,PRR70560,,,DSM 5974,lrp,,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,transcriptionalRegulator,,,,increased virulence (hypervirulence),,,,,,increased,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31681632,PubMed,10.3389/fcimb.2019.00356,Front Cell Infect Microbiol. 2019 Oct 17;9:356,ihsiuhuang@mail.ncku.edu.tw,R20291 lrp mutants displayed higher cytotoxicity towards both Caco-2 and Vero cells. epithelial colorectal adenocarcinoma cells,K Y Chen 2019,2019,1 gene,Chen-2019-The Transcriptional Regulator Lrp Co,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15108,PHI:9701,UniProt,A0A2T0ANK5,GenBank,PRR70560,,,DSM 5974,lrp,,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,transcriptionalRegulator,,,,increased virulence (hypervirulence),,,,,,increased,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,31681632,PubMed,10.3389/fcimb.2019.00356,Front Cell Infect Microbiol. 2019 Oct 17;9:356,ihsiuhuang@mail.ncku.edu.tw,R20291 lrp mutants displayed higher cytotoxicity towards both Caco-2 and Vero cells.Kidney epithelial cells,K Y Chen 2019,2019,1 gene,Chen-2019-The Transcriptional Regulator Lrp Co,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15109,PHI:9702,UniProt,A0A1I7RW40,,,,,,SapB3 (BXY_0495300),,,,,,,6326,Bursaphelenchus xylophilus,,,pine wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31559428,PubMed,10.1093/abbs/gmz100,Acta Biochim Biophys Sin (Shanghai). 2019 Sep 6;51(10):1071-1078,xqwu@njfu.edu.cn,The process of pine wilt disease was delayed when BxSapB3 was silenced in Bursaphelenchus xylophilus.,X Huang 2019,2019,1 gene,Huang-2019-Identification of a novel effector,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15110,PHI:9702,UniProt,A0A1I7RW40,,,,,,SapB3 (BXY_0495300),,,,,,,6326,Bursaphelenchus xylophilus,,,pine wilt,seed plants,3350,Pinus thunbergii (related: Japanese black pine),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31559428,PubMed,10.1093/abbs/gmz100,Acta Biochim Biophys Sin (Shanghai). 2019 Sep 6;51(10):1071-1078,xqwu@njfu.edu.cn,The process of pine wilt disease was delayed when BxSapB3 was silenced in Bursaphelenchus xylophilus.,X Huang 2019,2019,1 gene,Huang-2019-Identification of a novel effector,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15111,PHI:9703,UniProt,O94072,GenBank,CAA22028,,,1161,VMA4,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,vacuolar Hþ-ATPase complex,,,,loss of pathogenicity,,,,,,,,reduced,,no,fluconazole; terbinafine; amphotericin B; ZnCl2; CoCl2; CuSO4; MnCl2; NiSO4,fluconazole: CHEBI:46081; terbinafine: CHEBI:9448; amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,31542189,PubMed,10.1016/j.funbio.2019.06.002,Fungal Biol. 2019 Oct;123(10):709-722,joonkim@korea.ac.kr,Deleting VMA4 or VMA10 abolished vacuolar functions and hyphal morphogenesis.,S W Kim 2019,2019,2 genes,Kim-2019-Subunits of the vacuolar H+-ATPase co,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15112,PHI:9704,UniProt,Q59U85,GenBank,AOW27757,,,SC5314,vma10,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,vacuolar Hþ-ATPase complex,,,,loss of pathogenicity,,,,,,,,reduced,,no,fluconazole; terbinafine; amphotericin B,fluconazole: CHEBI:46081; terbinafine: CHEBI:9448; amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,31542189,PubMed,10.1016/j.funbio.2019.06.002,Fungal Biol. 2019 Oct;123(10):709-722,joonkim@korea.ac.kr,Deleting VMA4 or VMA10 abolished vacuolar functions and hyphal morphogenesis.,S W Kim 2019,2019,2 genes,Kim-2019-Subunits of the vacuolar H+-ATPase co,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15113,PHI:9703,UniProt,O94072,GenBank,CAA22028,,,1161,VMA4,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,vacuolar Hþ-ATPase complex,,,,loss of pathogenicity,,,,,,,,reduced,,no,fluconazole; terbinafine; amphotericin B; ZnCl2; CoCl2; CuSO4; MnCl2; NiSO4,fluconazole: CHEBI:46081; terbinafine: CHEBI:9448; amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,31542189,PubMed,10.1016/j.funbio.2019.06.002,Fungal Biol. 2019 Oct;123(10):709-722,joonkim@korea.ac.kr,Deleting VMA4 or VMA10 abolished vacuolar functions and hyphal morphogenesis.,S W Kim 2019,2019,2 genes,Kim-2019-Subunits of the vacuolar H+-ATPase co,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15114,PHI:9704,UniProt,Q59U85,GenBank,AOW27757,,,SC5314,vma10,,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,vacuolar Hþ-ATPase complex,,,,loss of pathogenicity,,,,,,,,reduced,,no,fluconazole; terbinafine; amphotericin B,fluconazole: CHEBI:46081; terbinafine: CHEBI:9448; amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,31542189,PubMed,10.1016/j.funbio.2019.06.002,Fungal Biol. 2019 Oct;123(10):709-722,joonkim@korea.ac.kr,Deleting VMA4 or VMA10 abolished vacuolar functions and hyphal morphogenesis.,S W Kim 2019,2019,2 genes,Kim-2019-Subunits of the vacuolar H+-ATPase co,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15115,PHI:9705,,no data found,,,,,,tal1,,,,,,,343,Xanthomonas translucens,152263,pv. cerealis strain NXtc01,bacterial leaf streak,monocots,4565,Triticum aestivum (related: bread wheat),cv. Yangmai 158,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31551976,PubMed,10.3389/fmicb.2019.02040,Front Microbiol. 2019 Sep 4;10:2040,gyouchen@sjtu.edu.cn,"The tal1 and tal-free deletion mutants were impaired with respect to symptom development and growth in wheat, suggesting that tal1 is a virulence factor in NXtc01.",S M A Shah 2019,2019,3 genes,Shah-2019-Tal1NXtc01 in Xanthomonas translucen,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15116,PHI:9706,,no data found,,,,,,tal2,,,,,,,343,Xanthomonas translucens,152263,pv. cerealis strain NXtc01,bacterial leaf streak,monocots,4565,Triticum aestivum (related: bread wheat),cv. Yangmai 158,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31551976,PubMed,10.3389/fmicb.2019.02040,Front Microbiol. 2019 Sep 4;10:2040,gyouchen@sjtu.edu.cn,"The tal1 and tal-free deletion mutants were impaired with respect to symptom development and growth in wheat, suggesting that tal1 is a virulence factor in NXtc01.",S M A Shah 2019,2019,3 genes,Shah-2019-Tal1NXtc01 in Xanthomonas translucen,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15117,PHI:9707,UniProt,A0A514EI82,GenBank,QDI05737,,,01,hrcC,,,,,,,343,Xanthomonas translucens,152263,pv. cerealis strain NXtc01,bacterial leaf streak,monocots,4565,Triticum aestivum (related: bread wheat),cv. Yangmai 158,,,leaf,type III secretion system outer membrane ring protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31551976,PubMed,10.3389/fmicb.2019.02040,Front Microbiol. 2019 Sep 4;10:2040,gyouchen@sjtu.edu.cn,The hrcC mutant was non-pathogenic on wheat and unable to elicit a hypersensitive response in the non-host Nicotiana benthamiana.,S M A Shah 2019,2019,3 genes,Shah-2019-Tal1NXtc01 in Xanthomonas translucen,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15118,PHI:9707,UniProt,A0A514EI82,GenBank,QDI05737,,,01,hrcC,,,,,,,343,Xanthomonas translucens,152263,pv. cerealis strain NXtc01,bacterial leaf streak,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,type III secretion system outer membrane ring protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31551976,PubMed,10.3389/fmicb.2019.02040,Front Microbiol. 2019 Sep 4;10:2040,gyouchen@sjtu.edu.cn,The hrcC mutant was non-pathogenic on wheat and unable to elicit a hypersensitive response in the non-host Nicotiana benthamiana.,S M A Shah 2019,2019,3 genes,Shah-2019-Tal1NXtc01 in Xanthomonas translucen,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15119,PHI:9708,UniProt,B2RLK2,GenBank,BAG34247,,,ATCC 33277,kgp,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),,,,gingival epithelium,lysine-specific cysteine proteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31697789,PubMed,10.1371/journal.ppat.1008124,PLoS Pathog. 2019 Nov 7;15(11):e1008124,amanoa@dent.osaka-u.ac.jp,"P. gingivalis gingipains disrupted barrier function of stratified squamous epithelium via degradation of JAM1, allowing bacterial virulence factors to penetrate into subepithelial tissues.",H Takeuchi 2019,2019,3 genes,Takeuchi-2019-Porphyromonas gingivalis induces,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15120,PHI:9709,UniProt,B2RM93,GenBank,BAG34488,,,ATCC 33277,rgpA,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),,,,gingival epithelium,arginine-specific cysteine proteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31697789,PubMed,10.1371/journal.ppat.1008124,PLoS Pathog. 2019 Nov 7;15(11):e1008124,amanoa@dent.osaka-u.ac.jp,"P. gingivalis gingipains disrupted barrier function of stratified squamous epithelium via degradation of JAM1, allowing bacterial virulence factors to penetrate into subepithelial tissues.",H Takeuchi 2019,2019,3 genes,Takeuchi-2019-Porphyromonas gingivalis induces,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15121,PHI:9710,UniProt,P95493,GenBank,AAB41892,,,HG66,rgpB,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),,,,gingival epithelium,arginine-specific cysteine proteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31697789,PubMed,10.1371/journal.ppat.1008124,PLoS Pathog. 2019 Nov 7;15(11):e1008124,amanoa@dent.osaka-u.ac.jp,"P. gingivalis gingipains disrupted barrier function of stratified squamous epithelium via degradation of JAM1, allowing bacterial virulence factors to penetrate into subepithelial tissues.",H Takeuchi 2019,2019,3 genes,Takeuchi-2019-Porphyromonas gingivalis induces,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15122,PHI:9711,UniProt,L8WVP3,GenBank,AG1IA_05142,,,,AGLIP1,,,,,,,456999,Rhizoctonia solani,,,sheath blight (rice),eudicots,3702,Arabidopsis thaliana (related: thale cress),cv. Ws-eds1,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31611861,PubMed,10.3389/fmicb.2019.02228,Front Microbiol. 2019 Sep 26;10:2228,lishuai@syau.edu.cn,AGLIP1 contributed to virulence by inhibiting PAMP-triggered immune signaling in plants.,S Li 2019,2019,1 gene,Li-2019-The Effector AGLIP1 in Rhizoctonia sol,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15123,PHI:9712,UniProt,A0A0W0EKQ2,GenBank,KTB24647,,,3A,srx1,,,,,,,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,sulfiredoxin,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15124,PHI:9713,UniProt,Q6FM56,GenBank,CAG61651,,,CBS 138,cta1,chromosome K,,,,,,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,catalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15125,PHI:9714,UniProt,Q6FMP9,GenBank,CAG61456,,,CBS 138,Tsa1,chromosome K,,,,,,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,thioredoxin domain-containing protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15126,PHI:9715,,no data found,,,,,,Tsa2,,,,,,,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,peroxiredoxin,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15127,PHI:9712,UniProt,A0A0W0EKQ2,GenBank,KTB24647,,,3A,srx1,,,,,,PHI:9713,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,sulfiredoxin,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15128,PHI:9713,UniProt,Q6FM56,GenBank,CAG61651,,,CBS 138,cta1,,,,,,PHI:9712,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,catalase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15129,PHI:9713,UniProt,Q6FM56,GenBank,CAG61651,,,CBS 138,cta1,,,,,,PHI:9714,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,catalase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15130,PHI:9714,UniProt,Q6FMP9,GenBank,CAG61456,,,CBS 138,Tsa1,,,,,,PHI:9713,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,thioredoxin domain-containing protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15131,PHI:9713,UniProt,Q6FM56,GenBank,CAG61651,,,CBS 138,cta1,,,,,,PHI:9715,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,catalase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15132,PHI:9715,,no data found,,,,,,Tsa2,,,,,,PHI:9713,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,peroxiredoxin,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15133,PHI:9714,UniProt,Q6FMP9,GenBank,CAG61456,,,CBS 138,Tsa1,,,,,,PHI:9715,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,thioredoxin domain-containing protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15134,PHI:9715,,no data found,,,,,,Tsa2,,,,,,PHI:9714,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,peroxiredoxin,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15135,PHI:9713,UniProt,Q6FM56,GenBank,CAG61651,,,CBS 138,cta1,,,,,,PHI:9714; PHI:9715,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,catalase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15136,PHI:9714,UniProt,Q6FMP9,GenBank,CAG61456,,,CBS 138,Tsa1,,,,,,PHI:9713; PHI:9715,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,thioredoxin domain-containing protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15137,PHI:9715,,no data found,,,,,,Tsa2,,,,,,PHI:9713; PHI:9714,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,peroxiredoxins,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15138,PHI:9716,,no data found,GenBank,KTB26212,,,3A,yap1,,,,,,,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,AP-1-like transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15139,PHI:9717,UniProt,Q6FTT1,GenBank,CAG59287,,,CBS 138,skn7,chromosome F,,,,,,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,response regulatory domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15140,PHI:9716,,no data found,GenBank,KTB26212,,,3A,yap1,,,,,,PHI:9717,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,AP-1-like transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15141,PHI:9717,UniProt,Q6FTT1,GenBank,CAG59287,,,CBS 138,skn7,chromosome F,,,,,PHI:9716,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,response regulatory domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15142,PHI:9718,UniProt,Q6FU62,GenBank,CAG59156,,,CBS 138,msn2,chromosome F,,,,,,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15143,PHI:9718,UniProt,Q6FU62,GenBank,CAG59156,,,CBS 138,msn2,chromosome F,,,,,PHI:9719,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15144,PHI:9719,UniProt,Q6FIM7,GenBank,CAG62897,,,CBS 138,msn4,chromosome M,,,,,PHI:9718,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15145,PHI:9716,,no data found,GenBank,KTB26212,,,3A,yap1,,,,,,PHI:9717; PHI:9718; PHI:9719,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,AP-1-like transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15146,PHI:9717,UniProt,Q6FTT1,GenBank,CAG59287,,,CBS 138,skn7,chromosome F,,,,,PHI:9716; PHI:9718; PHI:9719,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,response regulatory domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15147,PHI:9718,UniProt,Q6FU62,GenBank,CAG59156,,,CBS 138,msn2,chromosome F,,,,,PHI:9716; PHI:9717; PHI:9719,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15148,PHI:9719,UniProt,Q6FIM7,GenBank,CAG62897,,,CBS 138,msn4,chromosome M,,,,,PHI:9716; PHI:9717; PHI:9718,5478,Candida glabrata,,BG14,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31654781,PubMed,10.1016/j.fgb.2019.103287,Fungal Genet Biol. 2019 Oct 22;135:103287,cano@ipicyt.edu.mx,TSA1 and TSA2 are induced in the presence of neutrophils and required for survival in these phagocytic cells.,G Gutiérrez-Escobedo 2019,2019,8 genes,Gutierrez-Escob-2019-Candida glabrata peroxire,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15149,PHI:9720,UniProt,B1ML88,GenBank,CAM64733,,,ATCC:19977,MAB_4664,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15150,PHI:9721,UniProt,B1MKN8,GenBank,CAM61330,,,ATCC:19977,MAB_1242c,,,,,,PHI:9722; PHI:9723; PHI:9724; PHI:9725; PHI:9726,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15151,PHI:9722,UniProt,B1MKN9,GenBank,CAM61331,,,ATCC:19977,MAB_1243c,,,,,,PHI:9721; PHI:9723; PHI:9724; PHI:9725; PHI:9726,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15152,PHI:9723,UniProt,B1MKP0,GenBank,CAM61332,,,ATCC:19977,MAB_1244c,,,,,,PHI:9721; PHI:9722; PHI:9724; PHI:9725; PHI:9726,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15153,PHI:9724,UniProt,B1MKP1,GenBank,CAM61333,,,ATCC:19977,MAB_1245c,,,,,,PHI:9721; PHI:9722; PHI:9723; PHI:9725; PHI:9726,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15154,PHI:9725,UniProt,B1MKP2,GenBank,CAM61334,,,ATCC:19977,MAB_1246c,,,,,,PHI:9721; PHI:9722; PHI:9723; PHI:9724; PHI:9726,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15155,PHI:9726,UniProt,B1MKP3,GenBank,CAM61335,,,ATCC:19977,MAB_1247c,,,,,,PHI:9721; PHI:9722; PHI:9723; PHI:9724; PHI:9725,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15156,PHI:9727,UniProt,B1MMP1,GenBank,CAM61603,,,ATCC:19977,MAB_1517c,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,probable O-methyltransferase Omt,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15157,PHI:9728,UniProt,B1MBV8,GenBank,CAM62729,,,ATCC:19977,MAB_2649,,,,,,PHI:9729,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,putative membrane protein. MmpS family,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15158,PHI:9729,UniProt,B1MBV9,GenBank,CAM62730,,,ATCC:19977,MAB_2650,,,,,,PHI:9728,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,putative membrane protein. MmpL family,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15159,PHI:9730,UniProt,B1ML87,GenBank,CAM64732,,,ATCC:19977,MAB_4663,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15160,PHI:9731,UniProt,B1MM74,GenBank,CAM64859,,,ATCC:19977,MAB_4791c,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15161,PHI:9732,UniProt,B1MEC2,GenBank,CAM60186,,,ATCC:19977,MAB_0086,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,taurine catabolism dioxygenase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15162,PHI:9733,UniProt,B1MI08,GenBank,CAM60830,,,ATCC:19977,MAB_0734,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15163,PHI:9734,UniProt,B1MD88,GenBank,CAM63209,,,ATCC:19977,MAB_3132c,,,,,,PHI:9735; PHI:9736,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15164,PHI:9735,UniProt,B1MD89,GenBank,CAM63210,,,ATCC:19977,MAB_3133c,,,,,,PHI:9734; PHI:9736,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hemin transporter,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15165,PHI:9736,UniProt,B1MD90,GenBank,CAM63211,,,ATCC:19977,MAB_3134c,,,,,,PHI:9734; PHI:9735,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15166,PHI:9737,UniProt,B1MK71,GenBank,CAM64578,,,ATCC:19977,MAB_4509c,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15167,PHI:9738,UniProt,B1MKV6,GenBank,CAM64601,,,ATCC:19977,MAB_4532c,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,eis N-acetyl transferase protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15168,PHI:9739,UniProt,B1MIH6,GenBank,CAM64197,,,ATCC:19977,MAB_4124,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,eis N-acetyl transferase protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15169,PHI:9720,UniProt,B1ML88,GenBank,CAM64733,,,ATCC:19977,MAB_4664,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15170,PHI:9721,UniProt,B1MKN8,GenBank,CAM61330,,,ATCC:19977,MAB_1242c,,,,,,PHI:9722; PHI:9723; PHI:9724; PHI:9725; PHI:9726,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15171,PHI:9722,UniProt,B1MKN9,GenBank,CAM61331,,,ATCC:19977,MAB_1243c,,,,,,PHI:9721; PHI:9723; PHI:9724; PHI:9725; PHI:9726,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15172,PHI:9723,UniProt,B1MKP0,GenBank,CAM61332,,,ATCC:19977,MAB_1244c,,,,,,PHI:9721; PHI:9722; PHI:9724; PHI:9725; PHI:9726,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15173,PHI:9724,UniProt,B1MKP1,GenBank,CAM61333,,,ATCC:19977,MAB_1245c,,,,,,PHI:9721; PHI:9722; PHI:9723; PHI:9725; PHI:9726,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15174,PHI:9725,UniProt,B1MKP2,GenBank,CAM61334,,,ATCC:19977,MAB_1246c,,,,,,PHI:9721; PHI:9722; PHI:9723; PHI:9724; PHI:9726,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15175,PHI:9726,UniProt,B1MKP3,GenBank,CAM61335,,,ATCC:19977,MAB_1247c,,,,,,PHI:9721; PHI:9722; PHI:9723; PHI:9724; PHI:9725,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15176,PHI:9727,UniProt,B1MMP1,GenBank,CAM61603,,,ATCC:19977,MAB_1517c,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,probable O-methyltransferase Omt,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15177,PHI:9728,UniProt,B1MBV8,GenBank,CAM62729,,,ATCC:19977,MAB_2649,,,,,,PHI:9729,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,putative membrane protein. MmpS family,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15178,PHI:9729,UniProt,B1MBV9,GenBank,CAM62730,,,ATCC:19977,MAB_2650,,,,,,PHI:9728,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,putative membrane protein. MmpL family,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15179,PHI:9730,UniProt,B1ML87,GenBank,CAM64732,,,ATCC:19977,MAB_4663,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15180,PHI:9731,UniProt,B1MM74,GenBank,CAM64859,,,ATCC:19977,MAB_4791c,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15181,PHI:9732,UniProt,B1MEC2,GenBank,CAM60186,,,ATCC:19977,MAB_0086,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,taurine catabolism dioxygenase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15182,PHI:9733,UniProt,B1MI08,GenBank,CAM60830,,,ATCC:19977,MAB_0734,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15183,PHI:9734,UniProt,B1MD88,GenBank,CAM63209,,,ATCC:19977,MAB_3132c,,,,,,PHI:9735; PHI:9736,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15184,PHI:9735,UniProt,B1MD89,GenBank,CAM63210,,,ATCC:19977,MAB_3133c,,,,,,PHI:9734; PHI:9736,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hemin transporter,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15185,PHI:9736,UniProt,B1MD90,GenBank,CAM63211,,,ATCC:19977,MAB_3134c,,,,,,PHI:9734; PHI:9735,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15186,PHI:9737,UniProt,B1MK71,GenBank,CAM64578,,,ATCC:19977,MAB_4509c,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15187,PHI:9738,UniProt,B1MKV6,GenBank,CAM64601,,,ATCC:19977,MAB_4532c,,,,,,,36809,Mycobacteroides abscessus,,CIP 104536T,pulmonary disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,eis N-acetyl transferase protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15188,PHI:9722,UniProt,B1MKN9,GenBank,CAM61331,,,ATCC:19977,MAB_1243c,,,,,,,1774,Mycobacteroides chelonae,1460372,CCUG 47445,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15189,PHI:9727,UniProt,B1MMP1,GenBank,CAM61603,,,ATCC:19977,MAB_1517c,,,,,,,1774,Mycobacteroides chelonae,1460372,CCUG 47445,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,probable O-methyltransferase Omt,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15190,PHI:9728,UniProt,B1MBV8,GenBank,CAM62729,,,ATCC:19977,MAB_2649,,,,,,,1774,Mycobacteroides chelonae,1460372,CCUG 47445,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,putative membrane protein. MmpS family,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15191,PHI:9731,UniProt,B1MM74,GenBank,CAM64859,,,ATCC:19977,MAB_4791c,,,,,,,1774,Mycobacteroides chelonae,1460372,CCUG 47445,pulmonary disease,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31703112,PubMed,10.1371/journal.ppat.1008069,PLoS Pathog. 2019 Nov 8;15(11):e1008069,fabienne.misguich@uvsq.fr,"M. abscessus intra-amoeba and intra-murine macrophage transcriptomes revealed the capacity of M. abscessus to adapt to an intracellular lifestyle, with amoeba largely contributing to the enhancement of M. abscessus intra-murine macrophage survival.",V Dubois 2019,2019,20 genes,Dubois-2019-Mycobacterium abscessus virulence,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15192,PHI:9740,UniProt,Q4ICI6,GenBank,ESU10985,,,PH-1; NRRL 31084,FgSvf1 (FGSG_05072),chromosome 3,,,,,,5518,Fusarium graminearum,,GZ3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,inflorescence; spikelet,survival factor 1,,,glycolysis,reduced virulence,,,,,,reduced,reduced,reduced,reduced,no,NaCl; NaNO3; KCl; KNO3; H2O2; prochloraz,NaCl: CHEBI:26710; NaNO3 CAS no.: CAS:7631-99-4; KCl: CHEBI:32588; KNO3 CAS no.: CAS:7757-79-1; H2O2: CHEBI:16240; prochloraz: CHEBI:8434,,,,,gene deletion: full; gene complementation,,,YVS,31632215,PubMed,10.5423/PPJ.OA.03.2019.0070,Plant Pathol J. 2019 Oct;35(5):393-405,jungle@dau.ac.kr,"The FgSvf1 deletion mutant showed reduced resistance to osmotic, fungicide, and cold stress and reduced sensitivity to oxidative stress when compared to the WT strain.",T Li 2019,2019,1 gene,Li-2019-Survival Factor Gene FgSvf1 Is Require,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15193,PHI:9740,UniProt,Q4ICI6,GenBank,ESU10985,,,PH-1; NRRL 31084,FgSvf1 (FGSG_05072),chromosome 3,,,,,,5518,Fusarium graminearum,,GZ3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,inflorescence; spikelet,survival factor 1,,,glycolysis,unaffected pathogenicity,,,,,,wild type,wild type,wild type,wild type,no,NaCl; NaNO3; KCl; KNO3; H2O2; prochloraz,NaCl: CHEBI:26710; NaNO3 CAS no.: CAS:7631-99-4; KCl: CHEBI:32588; KNO3 CAS no.: CAS:7757-79-1; H2O2: CHEBI:16240; prochloraz: CHEBI:8434,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31632215,PubMed,10.5423/PPJ.OA.03.2019.0070,Plant Pathol J. 2019 Oct;35(5):393-405,jungle@dau.ac.kr,"The FgSvf1 deletion mutant showed reduced resistance to osmotic, fungicide, and cold stress and reduced sensitivity to oxidative stress when compared to the WT strain.",T Li 2019,2019,1 gene,Li-2019-Survival Factor Gene FgSvf1 Is Require,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15194,PHI:9741,UniProt,M4BU64,,,,,,cesA3 (HpaG810051),,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: thale cress),cv. Ws-eds1,,,seedling,cellulose synthase A3,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31557400,PubMed,10.1111/mpp.12863,Mol Plant Pathol. 2019 Nov;20(11):1523-1534,m.tor@worc.ac.uk,Antisense sRNAs inhibited spore germination and hence infection.,O Bilir 2019,2019,1 gene,Bilir-2019-Small RNA inhibits infection by dow,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15195,PHI:9742,UniProt,P0CP22,GenBank,AAW44776,,,JEC21,ccr4,chromosome 7,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,alveolar macrophage,major mRNA deadenylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31666517,PubMed,10.1038/s41467-019-12907-x,Nat Commun. 2019 Oct 30;10(1):4950,jcp25@buffalo.edu,"The mutant displayed increased exposure of cell wall glucans, and recognition by Dectin-1 results in increased phagocytosis by lung macrophages, linking mRNA decay to adaptation and immune evasion.",A L M Bloom 2019,2019,1 gene,Bloom-2019-Thermotolerance in the pathogen Cry,BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15196,PHI:9743,UniProt,I1RS35,GenBank,CEF83621,,,PH-1,Pex3 (FGSG_06942),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,integral peroxisomal membrane protein,,,peroxisome biogenesis,reduced virulence,,,,,,reduced,reduced,reduced; aberrant,,no,SDS; Congo red; caffeine; calcofluor white; sodium chloride; lithium chloride,SDS: CHEBI:8984; Congo red (CR): CHEBI:34653; caffeine: CHEBI:27732; calcofluor white (CFW): CHEBI:50011; sodium chloride: CHEBI:26710; lithium chloride: CHEBI:48607,,,,,gene deletion: full; gene complementation,,,YVS,31616386,PubMed,10.3389/fmicb.2019.02088,Front Microbiol. 2019 Sep 20;10:2088,wqchen@ippcaas.cn,Deletion of FgPex3 affected fatty acid beta-oxidation in F. graminearum and significantly reduced the utilization of fatty acids.,X Kong 2019,2019,1 gene,"Kong-2019-FgPex3, a Peroxisome Biogenesis Fact",BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15197,PHI:9743,UniProt,I1RS35,GenBank,CEF83621,,,PH-1,Pex3 (FGSG_06942),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Yangmai 158,,,spikelet,integral peroxisomal membrane protein,,,peroxisome biogenesis,reduced virulence,,,,,,reduced,reduced,reduced; aberrant,,no,SDS; Congo red; caffeine; calcofluor white; sodium chloride; lithium chloride,SDS: CHEBI:8984; Congo red (CR): CHEBI:34653; caffeine: CHEBI:27732; calcofluor white (CFW): CHEBI:50011; sodium chloride: CHEBI:26710; lithium chloride: CHEBI:48607,,,,,gene deletion: full; gene complementation,,,YVS,31616386,PubMed,10.3389/fmicb.2019.02088,Front Microbiol. 2019 Sep 20;10:2088,wqchen@ippcaas.cn,Deletion of FgPex3 affected fatty acid beta-oxidation in F. graminearum and significantly reduced the utilization of fatty acids.,X Kong 2019,2019,1 gene,"Kong-2019-FgPex3, a Peroxisome Biogenesis Fact",BATCH_097B,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15198,PHI:9744,UniProt,A0A0J9U8I9,GenBank,KNA94410,,,4287,FolVPS9 (FOXG_00470),chromosome 1,,,FolVps21,UniProt: A0A0J9U8I9; GenBank: KNA94410,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,root; stem,hypothetical protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31798569,PubMed,10.3389/fmicb.2019.02658,Front Microbiol. 2019 Nov 14;10:2658,oysq@yzu.edu.cn,"FolVps9 acted as a FolVps21 guanine nucleotide exchange factor (GEFs) to modulate endocytosis and autophagy, thereby controlling vegetative growth, asexual development and pathogenicity in Fol.",B Li 2019,2019,2 genes,"Li-2019-FolVps9, a Guanine Nucleotide Exchange",BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15199,PHI:9745,UniProt,A0A0D2XZG3,GenBank,KNB08569,,,4287,FolVPS21 (FOXG_09392),chromosome 9,,,FolVPS9,UniProt: A0A0D2XZG3; GenBank: KNB08569,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,root; stem,Rab family protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31798569,PubMed,10.3389/fmicb.2019.02658,Front Microbiol. 2019 Nov 14;10:2658,oysq@yzu.edu.cn,"FolVps9 acted as a FolVps21 guanine nucleotide exchange factor (GEFs) to modulate endocytosis and autophagy, thereby controlling vegetative growth, asexual development and pathogenicity in Fol.",B Li 2019,2019,2 genes,"Li-2019-FolVps9, a Guanine Nucleotide Exchange",BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15200,PHI:9746,UniProt,I1RII8,GenBank,ESU09578,,,PH-1,FGSG_03624,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Bobwhite; cv. Nandu,,,spikelet,"endo-1,4-beta-xylanase B",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,23337356,PubMed,10.1016/j.plaphy.2012.12.008,Plant Physiol Biochem. 2013 Mar;64:1-10,luca.sella@unipd.it,"F. graminearum mutants with the FG_03624 gene disrupted showed about 40% reduction of xylanase activity in comparison to the wild type, however, they were fully virulent on wheat.",L Sella 2013,2013,1 gene,Sella-2013-A Fusarium graminearum xylanase exp,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15201,PHI:9747,UniProt,A0A2S1GUJ8,GenBank,AWD93473,,,RUN1793,rip36,,,,,,,305,Ralstonia solanacearum,267608,RS1002,bacterial wilt,eudicots,119830,Solanum torvum (related: turkey berry),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,24745046,PubMed,10.1111/mpp.12079,Mol Plant Pathol. 2014 Apr;15(3):297-303,yuki@cc.okayama-u.ac.jp,RS1002-derived Δrip36 and rip36E149A mutants lost the ability to induce HR in S. torvum.,K Nahar 2014,2014,1 gene,Nahar-2014-Ralstonia solanacearum type III sec,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15202,PHI:9747,UniProt,A0A2S1GUJ8,GenBank,AWD93473,,,RUN1793,rip36,,Tnrip36E149A,,,,,305,Ralstonia solanacearum,267608,RS1002,bacterial wilt,eudicots,119830,Solanum torvum (related: turkey berry),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,24745046,PubMed,10.1111/mpp.12079,Mol Plant Pathol. 2014 Apr;15(3):297-303,yuki@cc.okayama-u.ac.jp,RS1002-derived Δrip36 and rip36E149A mutants lost the ability to induce HR in S. torvum.,K Nahar 2014,2014,1 gene,Nahar-2014-Ralstonia solanacearum type III sec,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15203,PHI:9748,UniProt,Q2G0X7,GenBank,ABD29550,,,NCTC 8325,SSL3 (SAOUHSC_00386),,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; kidney,staphylococcal superantigen-like protein 3,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28858870,PubMed,10.1159/000479100,J Innate Immun. 2017;9(6):561-573,karger@karger.com,Constitutive expression of SSL3 increased virulence compared to the parental strain in a murine model that was found to be TLR2 dependent.,K J Koymans 2017,2017,2 genes,Koymans-2017-The TLR2 Antagonist Staphylococca,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15204,PHI:9749,UniProt,Q2G1S8,GenBank,ABD29552,,,NCTC 8325,SSL4 (SAOUHSC_00389),,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; kidney,staphylococcal superantigen-like protein 3,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28858870,PubMed,10.1159/000479100,J Innate Immun. 2017;9(6):561-573,karger@karger.com,Constitutive expression of SSL3 increased virulence compared to the parental strain in a murine model that was found to be TLR2 dependent.,K J Koymans 2017,2017,2 genes,Koymans-2017-The TLR2 Antagonist Staphylococca,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15205,PHI:9748,UniProt,Q2G0X7,GenBank,ABD29550,,,NCTC 8325,SSL3 (SAOUHSC_00386),,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; kidney,staphylococcal superantigen-like protein 3,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28858870,PubMed,10.1159/000479100,J Innate Immun. 2017;9(6):561-573,karger@karger.com,Constitutive expression of SSL3 increased virulence compared to the parental strain in a murine model that was found to be TLR2 dependent.,K J Koymans 2017,2017,2 genes,Koymans-2017-The TLR2 Antagonist Staphylococca,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15206,PHI:9750,UniProt,A0A140GT66,GenBank,AMN36760,,,JP838,dgc,,,,,,,1502,Clostridium perfringens,,CP1,fatal canine hemorrhagic gastroenteritis; fatal foal necrotizing enterocolitis,birds,9031,Gallus gallus (related: chicken),White Plymouth Rock,,,jejunum,diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28888651,PubMed,10.1016/j.vetmic.2017.07.012,Vet Microbiol. 2017 Sep;208:69-73,prescott@uoguelph.ca,Mutation of either gene resulted in almost total attenuation of the mutants to cause necrotic enteritis in experimentally-infected broiler chickens.,V R Parreira 2017,2017,2 genes,Parreira-2017-Necrotic enteritis locus 1 digua,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15207,PHI:9751,UniProt,A0A127EH21,GenBank,AMN35281,,,JP838,pde,,,,,,,1502,Clostridium perfringens,,CP1,fatal canine hemorrhagic gastroenteritis; fatal foal necrotizing enterocolitis,birds,9031,Gallus gallus (related: chicken),White Plymouth Rock,,,jejunum,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28888651,PubMed,10.1016/j.vetmic.2017.07.012,Vet Microbiol. 2017 Sep;208:69-73,prescott@uoguelph.ca,Mutation of either gene resulted in almost total attenuation of the mutants to cause necrotic enteritis in experimentally-infected broiler chickens.,V R Parreira 2017,2017,2 genes,Parreira-2017-Necrotic enteritis locus 1 digua,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15208,PHI:9752,,no data found,,,,,,HbxA,,,,,,,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,reduced; aberrant,,reduced,increased,no,SDS,SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31757831,PubMed,10.1128/AEM.01779-19,Appl Environ Microbiol. 2019 Nov 22. pii: AEM.01779-19,amcalvo@niu.edu,Infection of neutropenic mice showed an increase in virulence in the hbxA deletion mutant compared to the A. fumigatus wild-type strain.,T Satterlee 2019,2019,1 gene,Satterlee-2019-The transcriptional regulator H,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15209,PHI:9753,UniProt,J4KMV6,GenBank,EJP64619,,,ARSEF 2860,BbpksP,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,polyketide synthase,,,,reduced virulence,,,,,,aberrant,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31751556,PubMed,10.1016/j.jip.2019.107280,J Invertebr Pathol. 2019 Nov 18;169:107280,fyh@swu.edu.cn,The lack of BbpksP gene reduced the UV-B tolerance of B. bassiana conidia.,J Wang 2019,2019,1 gene,"Wang-2019-A polyketide synthase, BbpksP, contr",BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15210,PHI:9754,UniProt,A0A0A2KLD7,GenBank,KGO62944,,,MD-8,PeSte12 (PEX1_013250),,,,,,,27334,Penicillium expansum,,CMP-1,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Smoothie,,,fruit,transcription factor,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full,,,YVS,28941893,PubMed,10.1016/j.fm.2017.08.005,Food Microbiol. 2018 Feb;69:123-135,pasantor@upv.es,"PeSte12 mutants resulted defective in asexual reproduction, producing less conidia.",P Sanchez-Torres 2018,2018,1 gene,Sanchez-Torres-2018-Unravelling the contributi,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15211,PHI:9755,UniProt,A0A0H2XI00,GenBank,ABD22510,,,USA300_FPR3757,phoP,,,,,,PHI:9756,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,alkaline phosphatase synthesis transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15212,PHI:9756,UniProt,A0A0H2XFS9,GenBank,ABD20494,,,USA300_FPR3757,phoR,,,,,,PHI:9755,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,sensory box histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15213,PHI:9757,UniProt,Q7A5Q2,GenBank,BAB42481,,,N315,PstS,,,,,,PHI:9758; PHI:9759; PHI:9760; PHI:9761,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,phosphate-binding protein/ thioredoxine reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15214,PHI:9758,,no data found,GenBank,VFS05436,,,NCTC8532,PstC,,,,,,PHI:9757; PHI:9759; PHI:9760; PHI:9761,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,"ABC-type phosphate transport system, permease component",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15215,PHI:9759,,no data found,GenBank,KFL07504,,,CDC 73-57501,PstA,,,,,,PHI:9757; PHI:9758; PHI:9760; PHI:9761,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,"phosphate ABC transporter, permease protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15216,PHI:9760,UniProt,Q2FYQ0,GenBank,ABD30480,,,NCTC 8325,PstB,,,,,,PHI:9757; PHI:9758; PHI:9759; PHI:9761,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,phosphate import ATP-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15217,PHI:9761,UniProt,A0A0H2JIX0,GenBank,GBV19690,,,M1K003,nptA,,,,,,PHI:9757; PHI:9758; PHI:9759; PHI:9760,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,Na+/phosphate symporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15218,PHI:9757,UniProt,Q7A5Q2,GenBank,BAB42481,,,N315,PstS,,,,,,PHI:9758; PHI:9759; PHI:9760; PHI:9761; PHI:9755; PHI:9756,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,phosphate-binding protein/ thioredoxine reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15219,PHI:9758,,no data found,GenBank,VFS05436,,,NCTC8532,PstC,,,,,,PHI:9757; PHI:9759; PHI:9760; PHI:9761; PHI:9755; PHI:9756,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,"ABC-type phosphate transport system, permease component",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15220,PHI:9759,,no data found,GenBank,KFL07504,,,CDC 73-57501,PstA,,,,,,PHI:9757; PHI:9758; PHI:9760; PHI:9761; PHI:9755; PHI:9756,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,"phosphate ABC transporter, permease protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15221,PHI:9760,UniProt,Q2FYQ0,GenBank,ABD30480,,,NCTC 8325,PstB,,,,,,PHI:9757; PHI:9758; PHI:9759; PHI:9761; PHI:9755; PHI:9756,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,phosphate import ATP-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15222,PHI:9761,UniProt,A0A0H2JIX0,GenBank,GBV19690,,,M1K003,nptA,,,,,,PHI:9757; PHI:9758; PHI:9759; PHI:9760; PHI:9755; PHI:9756,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,Na+/phosphate symporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15223,PHI:9755,UniProt,A0A0H2XI00,GenBank,ABD22510,,,USA300_FPR3757,phoP,,,,,,PHI:9757; PHI:9758; PHI:9759; PHI:9760; PHI:9761; PHI:9756,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,alkaline phosphatase synthesis transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15224,PHI:9756,UniProt,A0A0H2XFS9,GenBank,ABD20494,,,USA300_FPR3757,phoR,,,,,,PHI:9757; PHI:9758; PHI:9759; PHI:9760; PHI:9761; PHI:9755,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver,sensory box histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30061377,PubMed,10.1128/IAI.00371-18,Infect Immun. 2018 Sep 21;86(10). pii: e00371-18,kehlfie@illinois.edu,"PhoPR regulated factors, in addition to Pi transporters, were critical for staphylococcal pathogenesis.",J L Kelliher 2018,2018,1 gene,Kelliher-2018-PhoPR contributes to Staphylococ,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15225,PHI:9762,UniProt,Q2YRY5,GenBank,CAJ11717,,,2308,PykM (BAB1_1761),chromosome I,,,,,,29459,Brucella melitensis,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,manganese-dependent pyruvate kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30275278,PubMed,10.1128/JB.00471-18,J Bacteriol. 2018 Nov 26;200(24). pii: e00471-18,roopr@ecu.edu,PykM and PpdK made distinctly different contributions to carbon metabolism and virulence in these bacteria.,J E Pitzer 2018,2018,2 genes,Pitzer-2018-The manganese-dependent pyruvate k,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15226,PHI:9763,UniProt,Q2YMM9,GenBank,CAJ10481,,,2308,ppdK (BAB1_0525),chromosome I,,,,,,29459,Brucella melitensis,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,pyruvate phosphate dikinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30275278,PubMed,10.1128/JB.00471-18,J Bacteriol. 2018 Nov 26;200(24). pii: e00471-18,roopr@ecu.edu,PykM and PpdK made distinctly different contributions to carbon metabolism and virulence in these bacteria.,J E Pitzer 2018,2018,2 genes,Pitzer-2018-The manganese-dependent pyruvate k,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15227,PHI:9762,UniProt,Q2YRY5,GenBank,CAJ11717,,,2308,PykM (BAB1_1761),chromosome I,,,,,PHI:9763,29459,Brucella melitensis,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,manganese-dependent pyruvate kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30275278,PubMed,10.1128/JB.00471-18,J Bacteriol. 2018 Nov 26;200(24). pii: e00471-18,roopr@ecu.edu,PykM and PpdK made distinctly different contributions to carbon metabolism and virulence in these bacteria.,J E Pitzer 2018,2018,2 genes,Pitzer-2018-The manganese-dependent pyruvate k,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15228,PHI:9763,UniProt,Q2YMM9,GenBank,CAJ10481,,,2308,ppdK (BAB1_0525),chromosome I,,,,,PHI:9762,29459,Brucella melitensis,1310173,2308,ovine brucellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,pyruvate phosphate dikinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30275278,PubMed,10.1128/JB.00471-18,J Bacteriol. 2018 Nov 26;200(24). pii: e00471-18,roopr@ecu.edu,PykM and PpdK made distinctly different contributions to carbon metabolism and virulence in these bacteria.,J E Pitzer 2018,2018,2 genes,Pitzer-2018-The manganese-dependent pyruvate k,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15229,PHI:9764,UniProt,P00448,GenBank,AAB03041,,,K-12,sodA,,,,,,,562,Escherichia coli,,E058,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,superoxide dismutase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30602490,PubMed,10.1128/JB.00625-18,J Bacteriol. 2019 Feb 25;201(6). pii: e00625-18,gsong@yzu.edu.cn,The sodA mutant was significantly more easily phagocytosed by chicken macrophages than was the wild-type strain.,Q Gao 2019,2019,1 gene,Gao-2019-SodA contributes to the virulence of,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15230,PHI:9764,UniProt,P00448,GenBank,AAB03041,,,K-12,sodA,,,,,,,562,Escherichia coli,,E058,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,blood; liver; lung; spleen,superoxide dismutase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30602490,PubMed,10.1128/JB.00625-18,J Bacteriol. 2019 Feb 25;201(6). pii: e00625-18,gsong@yzu.edu.cn,The sodA mutant was significantly more easily phagocytosed by chicken macrophages than was the wild-type strain.,Q Gao 2019,2019,1 gene,Gao-2019-SodA contributes to the virulence of,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15231,PHI:9765,UniProt,Q9HWH7,GenBank,AE004837_2,,,PAO1,PpgL,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,metal-independent β-propeller gluconolactonase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30642898,PubMed,10.1128/IAI.00847-18,Infect Immun. 2019 Mar 25;87(4). pii: e00847-18,baorui@scu.edu.cn,Deletion of ppgL resulted in reduced biofilm formation and attenuated invasion phenotype.,Y J Song 2019,2019,1 gene,Song-2019-Structural and functional insights i,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15232,PHI:9766,UniProt,G4MUC7,GenBank,EHA54814,,,70-15,MoHOS2 (MGG_01633),chromosome 2,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nagdong,,,leaf,histone deacetylase,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31758396,PubMed,10.1007/s12275-019-9363-5,J Microbiol. 2019 Dec;57(12):1115-1125,jjeon@yu.ac.kr,Lack of MoHOS2 caused decrease in radial growth and impinged dramatically on asexual sporulation.,J Lee 2019,2019,1 gene,"Lee-2019-A histone deacetylase, MoHOS2 regulat",BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15233,PHI:9767,UniProt,A0A384JK85,GenBank,XP_001556179,,,B05.10,BcAOX (BC1G_05703),chromosome 6,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,ubiquinol terminal oxidase,,,mitochondrial oxidative phosphorylation,reduced virulence,,,,,,reduced; aberrant,,wild type,reduced,no,boscalid; fluopyram; azoxystrobin; pyraclostrobin; kresoxim-methyl; paraquat; fludioxonil; procymidone; H2O2; NaCl; KCl,boscalid: CHEBI:81822; fluopyram: CHEBI:83070; azoxystrobin: CHEBI:40909; pyraclostrobin: CHEBI:78780; kresoxim-methyl: CHEBI:2962; paraquat: CHEBI:34905; fludioxonil: CHEBI:81763; procymidone: CHEBI:8450; H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,31479404,PubMed,10.1094/PHYTO-01-19-0012-R,Phytopathology. 2019 Oct;109(10):1679-1688,cqzhang@zafu.edu.cn,The sensitivity of the mutants to quinone outside inhibitor fungicides and oxidative stress were increased.,Z Lin 2019,2019,1 gene,Lin-2019-Alternative Oxidase Is Involved in th,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15234,PHI:9767,UniProt,A0A384JK85,GenBank,XP_001556179,,,B05.10,BcAOX (BC1G_05703),chromosome 6,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,ubiquinol terminal oxidase,,,mitochondrial oxidative phosphorylation,reduced virulence,,,,,,reduced; aberrant,,wild type,reduced,no,boscalid; fluopyram; azoxystrobin; pyraclostrobin; kresoxim-methyl; paraquat; fludioxonil; procymidone; H2O2; NaCl; KCl,boscalid: CHEBI:81822; fluopyram: CHEBI:83070; azoxystrobin: CHEBI:40909; pyraclostrobin: CHEBI:78780; kresoxim-methyl: CHEBI:2962; paraquat: CHEBI:34905; fludioxonil: CHEBI:81763; procymidone: CHEBI:8450; H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,31479404,PubMed,10.1094/PHYTO-01-19-0012-R,Phytopathology. 2019 Oct;109(10):1679-1688,cqzhang@zafu.edu.cn,The sensitivity of the mutants to quinone outside inhibitor fungicides and oxidative stress were increased.,Z Lin 2019,2019,1 gene,Lin-2019-Alternative Oxidase Is Involved in th,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15235,PHI:9767,UniProt,A0A384JK85,GenBank,XP_001556179,,,B05.10,BcAOX (BC1G_05703),chromosome 6,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,leaf,ubiquinol terminal oxidase,,,mitochondrial oxidative phosphorylation,reduced virulence,,,,,,reduced; aberrant,,wild type,reduced,no,boscalid; fluopyram; azoxystrobin; pyraclostrobin; kresoxim-methyl; paraquat; fludioxonil; procymidone; H2O2; NaCl; KCl,boscalid: CHEBI:81822; fluopyram: CHEBI:83070; azoxystrobin: CHEBI:40909; pyraclostrobin: CHEBI:78780; kresoxim-methyl: CHEBI:2962; paraquat: CHEBI:34905; fludioxonil: CHEBI:81763; procymidone: CHEBI:8450; H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,31479404,PubMed,10.1094/PHYTO-01-19-0012-R,Phytopathology. 2019 Oct;109(10):1679-1688,cqzhang@zafu.edu.cn,The sensitivity of the mutants to quinone outside inhibitor fungicides and oxidative stress were increased.,Z Lin 2019,2019,1 gene,Lin-2019-Alternative Oxidase Is Involved in th,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15236,PHI:9768,UniProt,A0A4T2HBP6,GenBank,TII09320,,,WUSS425,SntA,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood; lung; brain,heme-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28823793,PubMed,10.1016/j.micpath.2017.08.018,Microb Pathog. 2017 Oct;111:145-155,rzhou@mail.hzau.edu.cn,Snta streptococcal heme-binding protein interacted with a host antioxidant protein and consequently inhibited its antioxidant activity.,Y Wan 2017,2017,1 gene,Wan-2017-Characterization of a novel streptoco,BATCH_098A,2019-12-01,MC,,,,,,,,,,,,,
,,Record 15237,PHI:9769,UniProt,Q92207,GenBank,CAA62214,,,1001,HOG1,,,,,,PHI:9770,5476,Candida albicans,,RM100,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,mitogen-activated protein kinase HOG1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31731583,PubMed,10.3390/jof5040107,J Fungi (Basel). 2019 Nov 15;5(4). pii: E107,realonso@ucm.es,"Sko1 was not required for virulence, but lack of Sko1 enhanced the virulence of a hog1 mutant.",V Urrialde 2019,2019,2 genes,Urrialde-2019-Deletion of the SKO1 Gene in a h,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15238,PHI:9770,UniProt,Q59VR1,GenBank,AOW26054,,,SC5314,SKO1,chromosome 1,,,,,PHI:9769,5476,Candida albicans,,RM100,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,transcriptional regulator SKO1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31731583,PubMed,10.3390/jof5040107,J Fungi (Basel). 2019 Nov 15;5(4). pii: E107,realonso@ucm.es,"Sko1 was not required for virulence, but lack of Sko1 enhanced the virulence of a hog1 mutant.",V Urrialde 2019,2019,2 genes,Urrialde-2019-Deletion of the SKO1 Gene in a h,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15239,PHI:9770,UniProt,Q59VR1,GenBank,AOW26054,,,SC5314,SKO1,chromosome 1,,,,,,5476,Candida albicans,,RM100,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,transcriptional regulator SKO1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31731583,PubMed,10.3390/jof5040107,J Fungi (Basel). 2019 Nov 15;5(4). pii: E107,realonso@ucm.es,"Sko1 was not required for virulence, but lack of Sko1 enhanced the virulence of a hog1 mutant.",V Urrialde 2019,2019,2 genes,Urrialde-2019-Deletion of the SKO1 Gene in a h,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15240,PHI:9769,UniProt,Q92207,GenBank,CAA62214,,,1001,HOG1,,,,,,,5476,Candida albicans,,RM100,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,intestine,mitogen-activated protein kinase HOG1,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31731583,PubMed,10.3390/jof5040107,J Fungi (Basel). 2019 Nov 15;5(4). pii: E107,realonso@ucm.es,"Sko1 was not required for virulence, but lack of Sko1 enhanced the virulence of a hog1 mutant.",V Urrialde 2019,2019,2 genes,Urrialde-2019-Deletion of the SKO1 Gene in a h,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15241,PHI:9769,UniProt,Q92207,GenBank,CAA62214,,,1001,HOG1,,,,,,PHI:9770,5476,Candida albicans,,RM100,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitogen-activated protein kinase HOG1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31731583,PubMed,10.3390/jof5040107,J Fungi (Basel). 2019 Nov 15;5(4). pii: E107,realonso@ucm.es,"Sko1 was not required for virulence, but lack of Sko1 enhanced the virulence of a hog1 mutant.",V Urrialde 2019,2019,2 genes,Urrialde-2019-Deletion of the SKO1 Gene in a h,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15242,PHI:9770,UniProt,Q59VR1,GenBank,AOW26054,,,SC5314,SKO1,chromosome 1,,,,,PHI:9769,5476,Candida albicans,,RM100,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,transcriptional regulator SKO1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31731583,PubMed,10.3390/jof5040107,J Fungi (Basel). 2019 Nov 15;5(4). pii: E107,realonso@ucm.es,"Sko1 was not required for virulence, but lack of Sko1 enhanced the virulence of a hog1 mutant.",V Urrialde 2019,2019,2 genes,Urrialde-2019-Deletion of the SKO1 Gene in a h,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15243,PHI:9770,UniProt,Q59VR1,GenBank,AOW26054,,,SC5314,SKO1,chromosome 1,,,,,,5476,Candida albicans,,RM100,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,transcriptional regulator SKO1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31731583,PubMed,10.3390/jof5040107,J Fungi (Basel). 2019 Nov 15;5(4). pii: E107,realonso@ucm.es,"Sko1 was not required for virulence, but lack of Sko1 enhanced the virulence of a hog1 mutant.",V Urrialde 2019,2019,2 genes,Urrialde-2019-Deletion of the SKO1 Gene in a h,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15244,PHI:9769,UniProt,Q92207,GenBank,CAA62214,,,1001,HOG1,,,,,,,5476,Candida albicans,,RM100,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitogen-activated protein kinase HOG1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31731583,PubMed,10.3390/jof5040107,J Fungi (Basel). 2019 Nov 15;5(4). pii: E107,realonso@ucm.es,"Sko1 was not required for virulence, but lack of Sko1 enhanced the virulence of a hog1 mutant.",V Urrialde 2019,2019,2 genes,Urrialde-2019-Deletion of the SKO1 Gene in a h,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15245,PHI:9771,UniProt,G4MKK5,GenBank,EHA58388,,,70-15,MoSNT2 (MGG_04421),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced; aberrant,,no,H2O2; calcofluor white; Congo red,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: partial; gene complementation,,,YVS,29929416,PubMed,10.1080/15548627.2018.1458171,Autophagy. 2018;14(9):1543-1561,xwchen88@163.com,Deletion mutants of MoSNT2 were compromised in autophagy homeostasis and displayed severe defects in autophagy-dependent fungal cell death and pathogenicity.,M He 2018,2018,1 gene,He-2018-MoSnt2-dependent deacetylation of hist,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15246,PHI:9772,UniProt,C1G4T3,GenBank,EEH45799,,,Pb18,TufM (PADG_01949),,,,,,,121759,Paracoccidioides brasiliensis,502780,Pb18,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitochondrial elongation factor Tu,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,31748561,PubMed,10.1038/s41598-019-51540-y,Sci Rep. 2019 Nov 20;9(1):17206,almeidaf@fcfar.unesp.br,"Silencing PbTUFM yielded phenotypic differences, such as altered translation elongation, respiratory defects, increased sensitivity of yeast cells to reactive oxygen stress, survival after macrophage phagocytosis, and reduced interaction with pneumocytes.",C M Marcos 2019,2019,1 gene,Marcos-2019-Down-regulation of TUFM impairs ho,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15247,PHI:9772,UniProt,C1G4T3,GenBank,EEH45799,,,Pb18,TufM (PADG_01949),,,,,,,121759,Paracoccidioides brasiliensis,502780,Pb18,infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,mitochondrial elongation factor Tu,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31748561,PubMed,10.1038/s41598-019-51540-y,Sci Rep. 2019 Nov 20;9(1):17206,almeidaf@fcfar.unesp.br,"Silencing PbTUFM yielded phenotypic differences, such as altered translation elongation, respiratory defects, increased sensitivity of yeast cells to reactive oxygen stress, survival after macrophage phagocytosis, and reduced interaction with pneumocytes.",C M Marcos 2019,2019,1 gene,Marcos-2019-Down-regulation of TUFM impairs ho,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15248,PHI:9772,UniProt,C1G4T3,GenBank,EEH45799,,,Pb18,TufM (PADG_01949),,,,,,,121759,Paracoccidioides brasiliensis,502780,Pb18,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitochondrial elongation factor Tu,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31748561,PubMed,10.1038/s41598-019-51540-y,Sci Rep. 2019 Nov 20;9(1):17206,almeidaf@fcfar.unesp.br,"Silencing PbTUFM yielded phenotypic differences, such as altered translation elongation, respiratory defects, increased sensitivity of yeast cells to reactive oxygen stress, survival after macrophage phagocytosis, and reduced interaction with pneumocytes.",C M Marcos 2019,2019,1 gene,Marcos-2019-Down-regulation of TUFM impairs ho,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15249,PHI:9772,UniProt,C1G4T3,GenBank,EEH45799,,,Pb18,TufM (PADG_01949),,,,,,,121759,Paracoccidioides brasiliensis,502780,Pb18,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,mitochondrial elongation factor Tu,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,31748561,PubMed,10.1038/s41598-019-51540-y,Sci Rep. 2019 Nov 20;9(1):17206,almeidaf@fcfar.unesp.br,"Silencing PbTUFM yielded phenotypic differences, such as altered translation elongation, respiratory defects, increased sensitivity of yeast cells to reactive oxygen stress, survival after macrophage phagocytosis, and reduced interaction with pneumocytes.",C M Marcos 2019,2019,1 gene,Marcos-2019-Down-regulation of TUFM impairs ho,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15250,PHI:9773,UniProt,Q87AG9,GenBank,AAO29688,,,Temecula1,EngXCA1 (PD1856),,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,leaf,extracellular endoglucanase precursor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31216219,PubMed,10.1094/MPMI-04-19-0096-R,"MPMI Vol. 32, No. 10, 2019, pp. 1402–1414",caroline.roper@ucr.edu,The loss of EngXCA1 and EngXCA2 in tandem reduces both X. fastidiosa virulence and population size and slows the rate of PD symptom development and progression.,B Ingel 2019,2019,2 genes,Ingel-2019-Xylella fastidiosa Endoglucanases M,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15251,PHI:9774,UniProt,Q87AH4,GenBank,AAO29683,,,Temecula1,EngXCA2 (PD1851),,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,leaf,"endo-1,4-beta-glucanase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31216219,PubMed,10.1094/MPMI-04-19-0096-R,"MPMI Vol. 32, No. 10, 2019, pp. 1402–1414",caroline.roper@ucr.edu,The loss of EngXCA1 and EngXCA2 in tandem reduces both X. fastidiosa virulence and population size and slows the rate of PD symptom development and progression.,B Ingel 2019,2019,2 genes,Ingel-2019-Xylella fastidiosa Endoglucanases M,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15252,PHI:9773,UniProt,Q87AG9,GenBank,AAO29688,,,Temecula1,EngXCA1 (PD1856),,,,,,PHI:9774,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,leaf,extracellular endoglucanase precursor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31216219,PubMed,10.1094/MPMI-04-19-0096-R,"MPMI Vol. 32, No. 10, 2019, pp. 1402–1414",caroline.roper@ucr.edu,The loss of EngXCA1 and EngXCA2 in tandem reduces both X. fastidiosa virulence and population size and slows the rate of PD symptom development and progression.,B Ingel 2019,2019,2 genes,Ingel-2019-Xylella fastidiosa Endoglucanases M,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15253,PHI:9774,UniProt,Q87AH4,GenBank,AAO29683,,,Temecula1,EngXCA2 (PD1851),,,,,,PHI:9773,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,leaf,"endo-1,4-beta-glucanase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31216219,PubMed,10.1094/MPMI-04-19-0096-R,"MPMI Vol. 32, No. 10, 2019, pp. 1402–1414",caroline.roper@ucr.edu,The loss of EngXCA1 and EngXCA2 in tandem reduces both X. fastidiosa virulence and population size and slows the rate of PD symptom development and progression.,B Ingel 2019,2019,2 genes,Ingel-2019-Xylella fastidiosa Endoglucanases M,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15254,PHI:9773,UniProt,Q87AG9,GenBank,AAO29688,,,Temecula1,EngXCA1 (PD1856),,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Cabernet Sauvignon,,,leaf,extracellular endoglucanase precursor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31216219,PubMed,10.1094/MPMI-04-19-0096-R,"MPMI Vol. 32, No. 10, 2019, pp. 1402–1414",caroline.roper@ucr.edu,The loss of EngXCA1 and EngXCA2 in tandem reduces both X. fastidiosa virulence and population size and slows the rate of PD symptom development and progression.,B Ingel 2019,2019,2 genes,Ingel-2019-Xylella fastidiosa Endoglucanases M,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15255,PHI:9774,UniProt,Q87AH4,GenBank,AAO29683,,,Temecula1,EngXCA2 (PD1851),,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Cabernet Sauvignon,,,leaf,"endo-1,4-beta-glucanase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31216219,PubMed,10.1094/MPMI-04-19-0096-R,"MPMI Vol. 32, No. 10, 2019, pp. 1402–1414",caroline.roper@ucr.edu,The loss of EngXCA1 and EngXCA2 in tandem reduces both X. fastidiosa virulence and population size and slows the rate of PD symptom development and progression.,B Ingel 2019,2019,2 genes,Ingel-2019-Xylella fastidiosa Endoglucanases M,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15256,PHI:9773,UniProt,Q87AG9,GenBank,AAO29688,,,Temecula1,EngXCA1 (PD1856),,,,,,PHI:9774,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Cabernet Sauvignon,,,leaf,extracellular endoglucanase precursor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31216219,PubMed,10.1094/MPMI-04-19-0096-R,"MPMI Vol. 32, No. 10, 2019, pp. 1402–1414",caroline.roper@ucr.edu,The loss of EngXCA1 and EngXCA2 in tandem reduces both X. fastidiosa virulence and population size and slows the rate of PD symptom development and progression.,B Ingel 2019,2019,2 genes,Ingel-2019-Xylella fastidiosa Endoglucanases M,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15257,PHI:9774,UniProt,Q87AH4,GenBank,AAO29683,,,Temecula1,EngXCA2 (PD1851),,,,,,PHI:9773,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes,eudicots,29760,Vitis vinifera (related: wine grape),cv. Cabernet Sauvignon,,,leaf,"endo-1,4-beta-glucanase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31216219,PubMed,10.1094/MPMI-04-19-0096-R,"MPMI Vol. 32, No. 10, 2019, pp. 1402–1414",caroline.roper@ucr.edu,The loss of EngXCA1 and EngXCA2 in tandem reduces both X. fastidiosa virulence and population size and slows the rate of PD symptom development and progression.,B Ingel 2019,2019,2 genes,Ingel-2019-Xylella fastidiosa Endoglucanases M,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15258,PHI:9775,,no data found,,,,,,Foc 1324,,,,,,,5507,Fusarium oxysporum,61366,f. sp. cubense race 4,wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),cv. BX,,,pseudostem,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31783262,PubMed,10.1016/j.micres.2019.126375,Microbiol Res. 2019 Nov 18;232:126375,cularmy@163.com,Knockout of Foc 1324 impaired the virulence of Foc 4 pathogen.,W Chang 2019,2019,1 gene,Chang-2019-Identification of mimp-associated e,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15259,PHI:9776,UniProt,Q9HZQ8,GenBank,AAG06327,,,PAO1,PaAP (PA2939),,,,,,,287,Pseudomonas aeruginosa,,S470,chronic lung infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,probable aminopeptidase,,,,reduced virulence,,,,,,,,,,no,colistin,colistin: CHEBI:37943,,,,,gene deletion: full; gene complementation,,,YVS,31744920,PubMed,10.1128/mBio.02548-19.,mBio. 2019 Nov 19;10(6). pii: e02548-19,kuehn@duke.edu,The PaAP mutant strain formed biofilms with substantially greater cellular biomass than the WT strain,C N Esoda 2019,2019,1 gene,Esoda-2019-Pseudomonas aeruginosa Leucine Amin,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15260,PHI:9776,UniProt,Q9HZQ8,GenBank,AAG06327,,,PAO1,PaAP (PA2939),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,chronic lung infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,probable aminopeptidase,,,,reduced virulence,,,,,,,,,,no,colistin,colistin: CHEBI:37943,,,,,gene deletion: full; gene complementation,,,YVS,31744920,PubMed,10.1128/mBio.02548-19.,mBio. 2019 Nov 19;10(6). pii: e02548-19,kuehn@duke.edu,The PaAP mutant strain formed biofilms with substantially greater cellular biomass than the WT strain,C N Esoda 2019,2019,1 gene,Esoda-2019-Pseudomonas aeruginosa Leucine Amin,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15261,PHI:9777,UniProt,A0A240FGL5,GenBank,ARR28601,,,BRIP44012,SIX2,,,,,,,5507,Fusarium oxysporum,1089451,f. sp. cubense TR4,wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),AAA group cv. Brazilian,,,leaf; rhizome; pseudostem,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,4-aminopyridine; barium(2+); clofilium,4-aminopyridine: CHEBI:34385; barium(2+): CHEBI:37136; clofilium: CHEBI:34649,,,,,gene deletion: full,,,YVS,31053331,PubMed,10.1016/j.funbio.2019.03.001,Fungal Biol. 2019 May;123(5):423-430,czhe@hainu.edu.cn,The plantlets inoculated with ΔSIX2 showed the similar disease progress as the WT strain treated ones.,B An 2019,2019,2 genes,An-2019-The effector SIX8 is required for viru,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15262,PHI:9778,UniProt,A0A240FGM0,GenBank,ARR28606,,,BRIP40340,SIX8,,,,,,,5507,Fusarium oxysporum,1089451,f. sp. cubense TR4,wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),AAA group cv. Brazilian,,,leaf; rhizome; pseudostem,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,4-aminopyridine; barium(2+); clofilium,4-aminopyridine: CHEBI:34385; barium(2+): CHEBI:37136; clofilium: CHEBI:34649,,,,,gene deletion: full; gene complementation,,,YVS,31053331,PubMed,10.1016/j.funbio.2019.03.001,Fungal Biol. 2019 May;123(5):423-430,czhe@hainu.edu.cn,"The plantlets inoculated with ΔSIX8 showed few disease symptoms after treatment for 5 week, with healthy leaves, rhizome and pseudostem, suggesting significant impairment in virulence of ΔSIX8.",B An 2019,2019,2 genes,An-2019-The effector SIX8 is required for viru,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15263,PHI:9779,UniProt,A0A509AS68,GenBank,VUC57675,,,ANKA,KCh2 (PB001143),chromosome 13,,,,,,5821,Plasmodium berghei,5823,ANKA,infection,rodents,10090,Mus musculus (related: house mouse),,,,,potassium channel K2,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,28864420,PubMed,10.1016/j.bbrc.2017.08.128,Biochem Biophys Res Commun. 2017 Nov 4;493(1):690-696,p.ellekvist@dadlnet.dk,The median oocyst numbers obtained with WT and Kch2-null parasites in the mosquito midguts were comparable indicating unperturbed transmission capability of both Kch2-null and WT parasites.,P Ellekvist 2017,2017,1 gene,Ellekvist-2017-Functional characterization of,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15264,PHI:9780,,no data found,,,,,,UvAc1,,,,,,,1159556,Ustilaginoidea virens,,P1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seed,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,,,,,reduced; aberrant,,wild type,aberrant,no,sodium dodecyl sulfate; calcofluor white; Congo red; sorbitol; sodium chloride; hydrogen peroxide; 3-isobutyl-1-methylxanthine (IBMX),sodium dodecyl sulfate: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:17924; sodium chloride: CHEBI:26710; hydrogen peroxide: CHEBI:16240; 3-isobutyl-1-methylxanthine (IBMX): CHEBI:48518,,,,,gene deletion: full; gene complementation,,,YVS,31063805,PubMed,10.1016/j.fgb.2019.04.017,Fungal Genet Biol. 2019 Aug;129:65-73,hfzhang@njau.edu.cn,"ΔUvac1 and ΔUvpdeH mutant fungi showed defects in conidial production, morphology, and germination; reduced toxicity against germinating rice seeds; and reduced virulence on rice panicles.",W Guo 2019,2019,2 genes,Guo-2019-The adenylate cyclase UvAc1 and phosp,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15265,PHI:9781,,no data found,,,,,,UvPdeH,,,,,,,1159556,Ustilaginoidea virens,,P1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seed,phosphodiesterase H,,,cAMP signaling pathway,reduced virulence,,,,,,reduced; aberrant,,wild type,aberrant,no,sodium dodecyl sulfate; calcofluor white; Congo red; sorbitol; sodium chloride; hydrogen peroxide; 3-isobutyl-1-methylxanthine (IBMX),sodium dodecyl sulfate: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:17924; sodium chloride: CHEBI:26710; hydrogen peroxide: CHEBI:16240; 3-isobutyl-1-methylxanthine (IBMX): CHEBI:48518,,,,,gene deletion: full; gene complementation,,,YVS,31063805,PubMed,10.1016/j.fgb.2019.04.017,Fungal Genet Biol. 2019 Aug;129:65-73,hfzhang@njau.edu.cn,"ΔUvac1 and ΔUvpdeH mutant fungi showed defects in conidial production, morphology, and germination; reduced toxicity against germinating rice seeds; and reduced virulence on rice panicles.",W Guo 2019,2019,2 genes,Guo-2019-The adenylate cyclase UvAc1 and phosp,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15266,PHI:9782,UniProt,J4WJ14,GenBank,EJP69785,,,ARSEF 2860,Mtf (BBA_01750),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitochondrial inner membrane protein mitofilin,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,sorbitol; hydrogen peroxide; menadione; Congo red,sorbitol: CHEBI:17924; Congo red: CHEBI:34653; menadione: CHEBI:28869; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31279975,PubMed,10.1016/j.fgb.2019.103250,Fungal Genet Biol. 2019 Nov;132:103250,yingsh@zju.edu.cn,"The BbMtf gene was required for conidiation and blastospore formation, and its absence led to a significant reduction in conidiation (40%) and blastospore yield (70%) in the mutant strain compared to the control.",J J Wang 2019,2019,1 gene,Wang-2019-Functional analysis of the mitochond,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15267,PHI:9783,UniProt,Q4WNC3,GenBank,EAL88541,,,Af293,rgsA (Afu6g06860),,,,,,,746128,Aspergillus fumigatus,330879,AF293.1,infection,rodents,10090,Mus musculus (related: house mouse),CrlOri:CD-1,,,lung,regulator of G protein signaling domain protein,,,,increased virulence (hypervirulence),,,,,,increased,,increased,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,31717953,PubMed,10.3390/ijms20225628,Int J Mol Sci. 2019 Nov 11;20(22). pii: E5628,jyu1@wisc.edu,The ΔrgsA spores showed enhanced tolerance against oxidative stressors.,H P Lwin 2019,2019,1 gene,"Lwin-2019-RgsA Attenuates the PKA Signaling, S",BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15268,PHI:9784,UniProt,G4NCH6,GenBank,EHA48273,,,70-15,mopex14/17,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,hypothetical protein,,,peroxisomal biogenesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31188736,PubMed,10.1094/PDIS-11-18-1964-RE,Plant Dis. 2019 Aug;103(8):1967-1973,cqzhang@zafu.edu.cn,The q-LAMP assay was successfully used to detect the presence of the virulence of M. oryzae strains (wild type) in comparison with that of the two mutant strains by quantifying the biomass within host tissue.,L Li 2019,2019,2 genes,Li-2019-Establishment of a Rapid Detection Met,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15269,PHI:9785,UniProt,G4ND53,GenBank,EHA48395,,,70-15,mopex19,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,hypothetical protein,,,peroxisomal biogenesis,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31188736,PubMed,10.1094/PDIS-11-18-1964-RE,Plant Dis. 2019 Aug;103(8):1967-1973,cqzhang@zafu.edu.cn,The q-LAMP assay was successfully used to detect the presence of the virulence of M. oryzae strains (wild type) in comparison with that of the two mutant strains by quantifying the biomass within host tissue.,L Li 2019,2019,2 genes,Li-2019-Establishment of a Rapid Detection Met,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15270,PHI:9786,,no data found,GenBank,AKG39814,,,ZY05719,VraSSS (ZY05719_02080),,,,,,PHI:9787,1307,Streptococcus suis,,ZY05719,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,histidine kinase,,,capsular polysaccharide (CPS) biosynthesis,reduced virulence,,,,,,,,,,no,ampicillin; amikacin; ceftriaxone; gentamicin; kanamycin; penicillin; streptomycin; vancomycin; bacitracin; colistin; polymyxin B; nisin,"ampicillin: CHEBI:28971; amikacin: CHEBI:2637; ceftriaxone: CHEBI:29007; gentamicin: CHEBI:17833; kanamycin: CHEBI:6104; penicillin: CHEBI:17334; streptomycin,  vancomycin: CHEBI:28001; bacitracin: CHEBI:28669; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; nisin: CHEBI:71629",,,,,gene deletion: full; gene complementation,,,YVS,29685990,PubMed,10.1128/IAI.00096-18,Infect Immun. 2018 Jun 21;86(7). pii: e00096-18,yaohch@njau.edu.cn,Downregulation of CPS biosynthesis caused by vraSRSS deletion was responsible for the increased adhesion to bEnd.3 cells and attenuated antiphagocytosis against RAW 264.7 cells.,X Zhong 2018,2018,2 genes,Zhong-2018-The two-component signaling system,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15271,PHI:9787,,no data found,GenBank,AKG39815,,,ZY05719,VraRSS (ZY05719_02085),,,,,,PHI:9786,1307,Streptococcus suis,,ZY05719,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,LuxR family transcriptional regulator,,,capsular polysaccharide (CPS) biosynthesis,reduced virulence,,,,,,,,,,no,ampicillin; amikacin; ceftriaxone; gentamicin; kanamycin; penicillin; streptomycin; vancomycin; bacitracin; colistin; polymyxin B; nisin,"ampicillin: CHEBI:28971; amikacin: CHEBI:2637; ceftriaxone: CHEBI:29007; gentamicin: CHEBI:17833; kanamycin: CHEBI:6104; penicillin: CHEBI:17334; streptomycin,  vancomycin: CHEBI:28001; bacitracin: CHEBI:28669; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; nisin: CHEBI:71629",,,,,gene deletion: full; gene complementation,,,YVS,29685990,PubMed,10.1128/IAI.00096-18,Infect Immun. 2018 Jun 21;86(7). pii: e00096-18,yaohch@njau.edu.cn,Downregulation of CPS biosynthesis caused by vraSRSS deletion was responsible for the increased adhesion to bEnd.3 cells and attenuated antiphagocytosis against RAW 264.7 cells.,X Zhong 2018,2018,2 genes,Zhong-2018-The two-component signaling system,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15272,PHI:9786,,no data found,GenBank,AKG39814,,,ZY05719,VraSSS (ZY05719_02080),,,,,,PHI:9787,1307,Streptococcus suis,,ZY05719,infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,histidine kinase,,,capsular polysaccharide (CPS) biosynthesis,reduced virulence,,,,,,,,,,no,ampicillin; amikacin; ceftriaxone; gentamicin; kanamycin; penicillin; streptomycin; vancomycin; bacitracin; colistin; polymyxin B; nisin,"ampicillin: CHEBI:28971; amikacin: CHEBI:2637; ceftriaxone: CHEBI:29007; gentamicin: CHEBI:17833; kanamycin: CHEBI:6104; penicillin: CHEBI:17334; streptomycin,  vancomycin: CHEBI:28001; bacitracin: CHEBI:28669; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; nisin: CHEBI:71629",,,,,gene deletion: full; gene complementation,,,YVS,29685990,PubMed,10.1128/IAI.00096-18,Infect Immun. 2018 Jun 21;86(7). pii: e00096-18,yaohch@njau.edu.cn,Downregulation of CPS biosynthesis caused by vraSRSS deletion was responsible for the increased adhesion to bEnd.3 cells and attenuated antiphagocytosis against RAW 264.7 cells.,X Zhong 2018,2018,2 genes,Zhong-2018-The two-component signaling system,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15273,PHI:9787,,no data found,GenBank,AKG39815,,,ZY05719,VraRSS (ZY05719_02085),,,,,,PHI:9786,1307,Streptococcus suis,,ZY05719,infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,LuxR family transcriptional regulator,,,capsular polysaccharide (CPS) biosynthesis,reduced virulence,,,,,,,,,,no,ampicillin; amikacin; ceftriaxone; gentamicin; kanamycin; penicillin; streptomycin; vancomycin; bacitracin; colistin; polymyxin B; nisin,"ampicillin: CHEBI:28971; amikacin: CHEBI:2637; ceftriaxone: CHEBI:29007; gentamicin: CHEBI:17833; kanamycin: CHEBI:6104; penicillin: CHEBI:17334; streptomycin,  vancomycin: CHEBI:28001; bacitracin: CHEBI:28669; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; nisin: CHEBI:71629",,,,,gene deletion: full; gene complementation,,,YVS,29685990,PubMed,10.1128/IAI.00096-18,Infect Immun. 2018 Jun 21;86(7). pii: e00096-18,yaohch@njau.edu.cn,Downregulation of CPS biosynthesis caused by vraSRSS deletion was responsible for the increased adhesion to bEnd.3 cells and attenuated antiphagocytosis against RAW 264.7 cells.,X Zhong 2018,2018,2 genes,Zhong-2018-The two-component signaling system,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15274,PHI:9786,,no data found,GenBank,AKG39814,,,ZY05719,VraSSS (ZY05719_02080),,,,,,PHI:9787,1307,Streptococcus suis,,ZY05719,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,histidine kinase,,,capsular polysaccharide (CPS) biosynthesis,reduced virulence,,,,,,,,,,no,ampicillin; amikacin; ceftriaxone; gentamicin; kanamycin; penicillin; streptomycin; vancomycin; bacitracin; colistin; polymyxin B; nisin,"ampicillin: CHEBI:28971; amikacin: CHEBI:2637; ceftriaxone: CHEBI:29007; gentamicin: CHEBI:17833; kanamycin: CHEBI:6104; penicillin: CHEBI:17334; streptomycin,  vancomycin: CHEBI:28001; bacitracin: CHEBI:28669; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; nisin: CHEBI:71629",,,,,gene deletion: full; gene complementation,,,YVS,29685990,PubMed,10.1128/IAI.00096-18,Infect Immun. 2018 Jun 21;86(7). pii: e00096-18,yaohch@njau.edu.cn,Downregulation of CPS biosynthesis caused by vraSRSS deletion was responsible for the increased adhesion to bEnd.3 cells and attenuated antiphagocytosis against RAW 264.7 cells.,X Zhong 2018,2018,2 genes,Zhong-2018-The two-component signaling system,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15275,PHI:9787,,no data found,GenBank,AKG39815,,,ZY05719,VraRSS (ZY05719_02085),,,,,,PHI:9786,1307,Streptococcus suis,,ZY05719,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,LuxR family transcriptional regulator,,,capsular polysaccharide (CPS) biosynthesis,reduced virulence,,,,,,,,,,no,ampicillin; amikacin; ceftriaxone; gentamicin; kanamycin; penicillin; streptomycin; vancomycin; bacitracin; colistin; polymyxin B; nisin,"ampicillin: CHEBI:28971; amikacin: CHEBI:2637; ceftriaxone: CHEBI:29007; gentamicin: CHEBI:17833; kanamycin: CHEBI:6104; penicillin: CHEBI:17334; streptomycin,  vancomycin: CHEBI:28001; bacitracin: CHEBI:28669; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; nisin: CHEBI:71629",,,,,gene deletion: full; gene complementation,,,YVS,29685990,PubMed,10.1128/IAI.00096-18,Infect Immun. 2018 Jun 21;86(7). pii: e00096-18,yaohch@njau.edu.cn,Downregulation of CPS biosynthesis caused by vraSRSS deletion was responsible for the increased adhesion to bEnd.3 cells and attenuated antiphagocytosis against RAW 264.7 cells.,X Zhong 2018,2018,2 genes,Zhong-2018-The two-component signaling system,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15276,PHI:9788,UniProt,P08191,GenBank,CAA29156,,,UTI89,fimH,,,,,,,562,Escherichia coli,,F149H1S2,salpingitis,birds,9031,Gallus gallus (related: chicken),Bovans Brown,,,oviduct,type 1 fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31767071,PubMed,10.1016/j.vetmic.2019.108445,Vet Microbiol. 2019 Dec;239:108445,jeo@sund.ku.dk,"No infection differences were observed between the UPEC UTI89 wild type and a mutant strain with knock-out of the well known virulence gene, fimH.",S Mortensen 2019,2019,1 gene,Mortensen-2019-Infectious potential of human d,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15277,PHI:9788,UniProt,P08191,GenBank,CAA29156,,,UTI89,fimH,,,,,,,562,Escherichia coli,,F149H1S2,salpingitis,birds,9031,Gallus gallus (related: chicken),Lohmann Brown,,,oviduct,type 1 fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31767071,PubMed,10.1016/j.vetmic.2019.108445,Vet Microbiol. 2019 Dec;239:108445,jeo@sund.ku.dk,"No infection differences were observed between the UPEC UTI89 wild type and a mutant strain with knock-out of the well known virulence gene, fimH.",S Mortensen 2019,2019,1 gene,Mortensen-2019-Infectious potential of human d,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15278,PHI:9788,UniProt,P08191,GenBank,CAA29156,,,UTI89,fimH,,,,,,,562,Escherichia coli,,UTI89,salpingitis,birds,9031,Gallus gallus (related: chicken),Bovans Brown,,,oviduct,type 1 fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31767071,PubMed,10.1016/j.vetmic.2019.108445,Vet Microbiol. 2019 Dec;239:108445,jeo@sund.ku.dk,"No infection differences were observed between the UPEC UTI89 wild type and a mutant strain with knock-out of the well known virulence gene, fimH.",S Mortensen 2019,2019,1 gene,Mortensen-2019-Infectious potential of human d,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15279,PHI:9788,UniProt,P08191,GenBank,CAA29156,,,UTI89,fimH,,,,,,,562,Escherichia coli,,UTI89,salpingitis,birds,9031,Gallus gallus (related: chicken),Lohmann Brown,,,oviduct,type 1 fimbriae,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31767071,PubMed,10.1016/j.vetmic.2019.108445,Vet Microbiol. 2019 Dec;239:108445,jeo@sund.ku.dk,"No infection differences were observed between the UPEC UTI89 wild type and a mutant strain with knock-out of the well known virulence gene, fimH.",S Mortensen 2019,2019,1 gene,Mortensen-2019-Infectious potential of human d,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15280,PHI:9789,,no data found,,,,,,EsR240,,,,,,,636,Edwardsiella tarda,,ET13,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,small non-coding RNA,,,,reduced virulence,,,,,,,,,,no,sodium chloride; hydrogen peroxide,sodium chloride: CHEBI:26710; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30955819,PubMed,10.1016/j.vetmic.2019.03.023,Vet Microbiol. 2019 Apr;231:254-263,dgao2@seu.edu.cn,EsR240 mutants exhibited decreased survival under stress conditions.,D Gao 2019,2019,1 gene,"Gao-2019-EsR240, a non-coding sRNA, is require",BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15281,PHI:9789,,no data found,,,,,,EsR240,,,,,,,636,Edwardsiella tarda,,ET13,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small non-coding RNA,,,,reduced virulence,,,,,,,,,,no,sodium chloride; hydrogen peroxide,sodium chloride: CHEBI:26710; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30955819,PubMed,10.1016/j.vetmic.2019.03.023,Vet Microbiol. 2019 Apr;231:254-263,dgao2@seu.edu.cn,EsR240 mutants exhibited decreased survival under stress conditions.,D Gao 2019,2019,1 gene,"Gao-2019-EsR240, a non-coding sRNA, is require",BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15282,PHI:9790,UniProt,Q03470,GenBank,AAA23028,,,UA580,gyrA,,"Thr86Ile; Thr86Ile, Asp90Asn",,,,,197,Campylobacter jejuni,192222,NCTC 11168,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DNA gyrase subunit A,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,nalidixic acid; ciprofloxacin,nalidixic acid: CHEBI:100147; ciprofloxacin: CHEBI:100241,,,,,gene mutation: characterised,,,YVS,31796849,PubMed,10.1038/s41598-019-54620-1,Sci Rep. 2019 Dec 3;9(1):18216,Tadhg.OCroinin@ucd.ie,Fluoroquinolone resistance in C. jejuni was associated with an increase in virulence and the ability to form viable biofilms in oxygen rich environments.,M V X Whelan 2019,2019,2 genes,Whelan-2019-Acquisition of fluoroquinolone res,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15283,PHI:9790,UniProt,Q03470,GenBank,AAA23028,,,UA580,gyrA,,Thr86Ile,,,,PHI:9791,197,Campylobacter jejuni,192222,NCTC 11168,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DNA gyrase subunit A,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,nalidixic acid; ciprofloxacin,nalidixic acid: CHEBI:100147; ciprofloxacin: CHEBI:100241,,,,,gene mutation: characterised,,,YVS,31796849,PubMed,10.1038/s41598-019-54620-1,Sci Rep. 2019 Dec 3;9(1):18216,Tadhg.OCroinin@ucd.ie,Fluoroquinolone resistance in C. jejuni was associated with an increase in virulence and the ability to form viable biofilms in oxygen rich environments.,M V X Whelan 2019,2019,2 genes,Whelan-2019-Acquisition of fluoroquinolone res,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15284,PHI:9791,UniProt,O87667,GenBank,CAL34184,,,NCTC 11168,gyrB,,Leu458Lys,,,,PHI:9790,197,Campylobacter jejuni,192222,NCTC 11168,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DNA gyrase subunit B,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,nalidixic acid; ciprofloxacin,nalidixic acid: CHEBI:100147; ciprofloxacin: CHEBI:100241,,,,,gene mutation: characterised,,,YVS,31796849,PubMed,10.1038/s41598-019-54620-1,Sci Rep. 2019 Dec 3;9(1):18216,Tadhg.OCroinin@ucd.ie,Fluoroquinolone resistance in C. jejuni was associated with an increase in virulence and the ability to form viable biofilms in oxygen rich environments.,M V X Whelan 2019,2019,2 genes,Whelan-2019-Acquisition of fluoroquinolone res,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15285,PHI:9790,UniProt,Q03470,GenBank,AAA23028,,,UA580,gyrA,,"Thr86Ile; Thr86Ile, Asp90Asn",,,,,197,Campylobacter jejuni,192222,NCTC 11168,infection,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,epithelial cell,DNA gyrase subunit A,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,nalidixic acid; ciprofloxacin,nalidixic acid: CHEBI:100147; ciprofloxacin: CHEBI:100241,,,,,gene mutation: characterised,,,YVS,31796849,PubMed,10.1038/s41598-019-54620-1,Sci Rep. 2019 Dec 3;9(1):18216,Tadhg.OCroinin@ucd.ie,Fluoroquinolone resistance in C. jejuni was associated with an increase in virulence and the ability to form viable biofilms in oxygen rich environments.,M V X Whelan 2019,2019,2 genes,Whelan-2019-Acquisition of fluoroquinolone res,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15286,PHI:9790,UniProt,Q03470,GenBank,AAA23028,,,UA580,gyrA,,Thr86Ile,,,,PHI:9791,197,Campylobacter jejuni,192222,NCTC 11168,infection,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,epithelial cell,DNA gyrase subunit A,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,nalidixic acid; ciprofloxacin,nalidixic acid: CHEBI:100147; ciprofloxacin: CHEBI:100241,,,,,gene mutation: characterised,,,YVS,31796849,PubMed,10.1038/s41598-019-54620-1,Sci Rep. 2019 Dec 3;9(1):18216,Tadhg.OCroinin@ucd.ie,Fluoroquinolone resistance in C. jejuni was associated with an increase in virulence and the ability to form viable biofilms in oxygen rich environments.,M V X Whelan 2019,2019,2 genes,Whelan-2019-Acquisition of fluoroquinolone res,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15287,PHI:9791,UniProt,O87667,GenBank,CAL34184,,,NCTC 11168,gyrB,,Leu458Lys,,,,PHI:9790,197,Campylobacter jejuni,192222,NCTC 11168,infection,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,epithelial cell,DNA gyrase subunit B,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,nalidixic acid; ciprofloxacin,nalidixic acid: CHEBI:100147; ciprofloxacin: CHEBI:100241,,,,,gene mutation: characterised,,,YVS,31796849,PubMed,10.1038/s41598-019-54620-1,Sci Rep. 2019 Dec 3;9(1):18216,Tadhg.OCroinin@ucd.ie,Fluoroquinolone resistance in C. jejuni was associated with an increase in virulence and the ability to form viable biofilms in oxygen rich environments.,M V X Whelan 2019,2019,2 genes,Whelan-2019-Acquisition of fluoroquinolone res,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15288,PHI:9792,UniProt,Q9ZM18,GenBank,AAD05980,,,J99,HtrA,,,,,,,210,Helicobacter pylori,102616,N6,infection,primates,9606,Homo sapiens (related: human),MKN28 cell line,,,gastric adenocarcinoma cell,periplasmic serine endoprotease DegP-like,,,,reduced virulence,,,,,,,,wild type,,no,sucrose; NaCl; MgCl2; metronidazole; puromycin,sodium chloride: CHEBI:26710; sucrose: CHEBI:17992; magnesium dichloride: CHEBI:6636; metronidazole: CHEBI:6909; puromycin: CHEBI:17939,,,,,gene deletion: full; gene complementation,,,YVS,31796064,PubMed,10.1186/s12964-019-0481-9,Cell Commun Signal. 2019 Dec 3;17(1):161,steffen.backert@fau.de,Expression of HtrA by H. pylori was important for disruption of E-cadherin in the adherens junctions of polarized MKN28 cells.,U Zarzecka 2019,2019,1 gene,Zarzecka-2019-Chaperone activity of serine pro,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15289,PHI:9792,UniProt,Q9ZM18,GenBank,AAD05980,,,J99,HtrA,,HtrA S221A,,,,,210,Helicobacter pylori,102616,N6,infection,primates,9606,Homo sapiens (related: human),MKN28 cell line,,,gastric adenocarcinoma cell,periplasmic serine endoprotease DegP-like,,,,reduced virulence,,,,,,,,wild type,,no,sucrose; NaCl; MgCl2; metronidazole; puromycin,sodium chloride: CHEBI:26710; sucrose: CHEBI:17992; magnesium dichloride: CHEBI:6636; metronidazole: CHEBI:6909; puromycin: CHEBI:17939,,,,,gene mutation; gene complementation,,,YVS,31796064,PubMed,10.1186/s12964-019-0481-9,Cell Commun Signal. 2019 Dec 3;17(1):161,steffen.backert@fau.de,Expression of HtrA by H. pylori was important for disruption of E-cadherin in the adherens junctions of polarized MKN28 cells.,U Zarzecka 2019,2019,1 gene,Zarzecka-2019-Chaperone activity of serine pro,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15290,PHI:9793,UniProt,G2WX41,GenBank,EGY21296,,,VdLs.17,VdOCH1,chromosome 3,,,,,,27337,Verticillium dahliae,,VdGn3,yellow wilt (sunflower),eudicots,4232,Helianthus annuus (related: common sunflower),cv. LD5009,,,seedling,"initiation-specific alpha-1,6-mannosyltransferase",,,,reduced virulence,,,yes,,,reduced,,aberrant,reduced,no,sodium dodecyl sulfate; congo red,sodium dodecyl sulfate: CHEBI:8984; congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31196523,PubMed,10.1016/j.funbio.2019.05.007,Fungal Biol. 2019 Jul;123(7):539-546,zhaojun@imau.edu.cn,"ΔVdOCH1 mutants were more sensitive to the cell wall perturbing reagents, such as SDS and Congo red, lost their penetration ability through cellophane membrane, and exhibited dramatically decreased pathogenicity to sunflower.",J Zhang 2019,2019,1 gene,"Zhang-2019-The alpha-1,6-mannosyltransferase V",BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15291,PHI:9793,UniProt,G2WX41,GenBank,EGY21296,,,VdLs.17,VdOCH1,chromosome 3,T-DNA insertion mutant,,,,,27337,Verticillium dahliae,,VdGn3,yellow wilt (sunflower),eudicots,4232,Helianthus annuus (related: common sunflower),cv. LD5009,,,seedling,"initiation-specific alpha-1,6-mannosyltransferase",,,,reduced virulence,,,yes,,,reduced,,aberrant,reduced,no,sodium dodecyl sulfate; congo red,sodium dodecyl sulfate: CHEBI:8984; congo red: CHEBI:34653,,,,,gene mutation,,,YVS,31196523,PubMed,10.1016/j.funbio.2019.05.007,Fungal Biol. 2019 Jul;123(7):539-546,zhaojun@imau.edu.cn,"ΔVdOCH1 mutants were more sensitive to the cell wall perturbing reagents, such as SDS and Congo red, lost their penetration ability through cellophane membrane, and exhibited dramatically decreased pathogenicity to sunflower.",J Zhang 2019,2019,1 gene,"Zhang-2019-The alpha-1,6-mannosyltransferase V",BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15292,PHI:9794,UniProt,A0A1A5HM84,GenBank,HXb2AQY22494,,,HXb2,GldK (AS87_08785),,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood,gliding motility lipoprotein GldK,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30955831,PubMed,10.1016/j.vetmic.2019.03.006,Vet Microbiol. 2019 Apr;231:93-99,yus@shvri.ac.cn,"The mutant strain Yb2ΔgldK displayed defective gliding motility on agar plates, reduced protease activity, and a reduced capacity for protein secretion.",K K Malhi 2019,2019,1 gene,Malhi-2019-Riemerella anatipestifer gene AS87_,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15293,PHI:9794,UniProt,A0A1A5HM84,GenBank,HXb2AQY22494,,,HXb2,GldK (AS87_08785),,,,,,,34085,Riemerella anatipestifer,1455062,Yb2,septicemia,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,gliding motility lipoprotein GldK,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30955831,PubMed,10.1016/j.vetmic.2019.03.006,Vet Microbiol. 2019 Apr;231:93-99,yus@shvri.ac.cn,Both the adherence and invasion capacities of mutant strain Yb2ΔgldK were significantly reduced compared with those of Yb2.Kidney epithelial cells,K K Malhi 2019,2019,1 gene,Malhi-2019-Riemerella anatipestifer gene AS87_,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15294,PHI:9795,,no data found,,,,,,SypA,,,,,,,50340,Pseudomonas fuscovaginae,1246628,DAR77795,sheath brown rot,monocots,4530,Oryza sativa (related: rice),cv. Amaroo; cv. Nipponbare,,,seedling,syringopeptin synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31804903,PubMed,10.1094/PHYTO-07-19-0235-R,Phytopathology. 2019 Dec 5,niruwee@gmail.com,"Rice and wheat inoculated with sypA mutants caused a significantly higher number of roots, length of roots and seedling height compared to their respective wild types.",N Weeraratne 2019,2019,1 gene,Weeraratne-2019-Syringopeptin contributes to t,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15295,PHI:9795,,no data found,,,,,,SypA,,,,,,,50340,Pseudomonas fuscovaginae,1367450,DAR77800,sheath brown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Rosella,,,seedling,syringopeptin synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31804903,PubMed,10.1094/PHYTO-07-19-0235-R,Phytopathology. 2019 Dec 5,niruwee@gmail.com,"Rice and wheat inoculated with sypA mutants caused a significantly higher number of roots, length of roots and seedling height compared to their respective wild types.",N Weeraratne 2019,2019,1 gene,Weeraratne-2019-Syringopeptin contributes to t,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15296,PHI:9795,,no data found,,,,,,SypA,,,,,,,50340,Pseudomonas fuscovaginae,1246628,DAR77795,sheath brown rot,monocots,4530,Oryza sativa (related: rice),cv. Amaroo; cv. Nipponbare,,,seedling,syringopeptin synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31804903,PubMed,10.1094/PHYTO-07-19-0235-R,Phytopathology. 2019 Dec 5,niruwee@gmail.com,"Rice and wheat inoculated with sypA mutants caused a significantly higher number of roots, length of roots and seedling height compared to their respective wild types.",N Weeraratne 2019,2019,1 gene,Weeraratne-2019-Syringopeptin contributes to t,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15297,PHI:9795,,no data found,,,,,,SypA,,,,,,,50340,Pseudomonas fuscovaginae,1367450,DAR77800,sheath brown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Rosella,,,seedling,syringopeptin synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31804903,PubMed,10.1094/PHYTO-07-19-0235-R,Phytopathology. 2019 Dec 5,niruwee@gmail.com,"Rice and wheat inoculated with sypA mutants caused a significantly higher number of roots, length of roots and seedling height compared to their respective wild types.",N Weeraratne 2019,2019,1 gene,Weeraratne-2019-Syringopeptin contributes to t,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15298,PHI:9796,UniProt,A0A0K0GFI3,GenBank,ACD56737,,,PXO99A,hrpE,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,blight,monocots,4530,Oryza sativa (related: rice),,,,leaf,type III pilin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31752133,PubMed,10.3390/microorganisms7110572,Microorganisms. 2019 Nov 18;7(11). pii: E572,lyZhang@sdau.edu.cn,Deletion of hrpE affected the pathogen virulence in a host and the hypersensitive response in a non-host.,T M M Sheikh 2019,2019,1 gene,Sheikh-2019-The Type III Accessory Protein Hrp,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15299,PHI:9796,UniProt,A0A0K0GFI3,GenBank,ACD56737,,,PXO99A,hrpE,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,type III pilin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31752133,PubMed,10.3390/microorganisms7110572,Microorganisms. 2019 Nov 18;7(11). pii: E572,lyZhang@sdau.edu.cn,Deletion of hrpE affected the pathogen virulence in a host and the hypersensitive response in a non-host.,T M M Sheikh 2019,2019,1 gene,Sheikh-2019-The Type III Accessory Protein Hrp,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15300,PHI:9797,UniProt,E0WJS2,GenBank,CBV36593,,,RE7006,CagQ,,,,,,,210,Helicobacter pylori,85962,26695,chronic gastritis,primates,9606,Homo sapiens (related: human),GES-1 cell line,,,gastric epithelial cell,Cag pathogenicity island protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29306012,PubMed,10.1016/j.micpath.2017.12.076,Microb Pathog. 2018 Mar;116:1-7,shaoshihe2006@163.com,CagQ knock out inhibited CagA-induced apoptosis in gastric epithelial cells.,Y Yao 2018,2018,1 gene,Yao-2018-Preliminary study and bioinformatics,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15301,PHI:9798,UniProt,Q9A0L9,GenBank,AAK33667,,,SF370,adcA,,,,,,PHI:9799,1314,Streptococcus pyogenes,,5448,skin lesion,rodents,10090,Mus musculus (related: house mouse),AlbPLG1<+/->,,,skin; blood,zinc-binding protein,,,,reduced virulence,,,,,,,,,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,29581188,PubMed,10.1128/IAI.00048-18,Infect Immun. 2018 May 22;86(6),y.ong@uq.edu.au,"The ΔczcD mutant and the ΔadcA ΔadcAII mutant were less virulent than 5448 GAS WT, with the ΔadcA ΔadcAII mutant showing the greatest attenuation of virulence.",C Y Ong 2018,2018,4 genes,Ong-2018-The role of zinc acquisition and zinc,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15302,PHI:9799,UniProt,Q9A0D2,,,,,,adcAII,,,,,,PHI:9798,1314,Streptococcus pyogenes,,5448,skin lesion,rodents,10090,Mus musculus (related: house mouse),AlbPLG1<+/->,,,skin; blood,zinc-binding protein,,,,reduced virulence,,,,,,,,,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,29581188,PubMed,10.1128/IAI.00048-18,Infect Immun. 2018 May 22;86(6),y.ong@uq.edu.au,"The ΔczcD mutant and the ΔadcA ΔadcAII mutant were less virulent than 5448 GAS WT, with the ΔadcA ΔadcAII mutant showing the greatest attenuation of virulence.",C Y Ong 2018,2018,4 genes,Ong-2018-The role of zinc acquisition and zinc,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15303,PHI:9800,UniProt,Q1JHF9,GenBank,ABF33777,,,MGAS10270,czcD,,,,,,,1314,Streptococcus pyogenes,,5448,skin lesion,rodents,10090,Mus musculus (related: house mouse),AlbPLG1<+/->,,,skin; blood,cobalt-zinc-cadmium resistance protein,,,,reduced virulence,,,,,,,,,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,29581188,PubMed,10.1128/IAI.00048-18,Infect Immun. 2018 May 22;86(6),y.ong@uq.edu.au,"The ΔczcD mutant and the ΔadcA ΔadcAII mutant were less virulent than 5448 GAS WT, with the ΔadcA ΔadcAII mutant showing the greatest attenuation of virulence.",C Y Ong 2018,2018,4 genes,Ong-2018-The role of zinc acquisition and zinc,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15304,PHI:9798,UniProt,Q9A0L9,GenBank,AAK33667,,,SF370,adcA,,,,,,PHI:9799,1314,Streptococcus pyogenes,,5448,skin lesion,primates,9606,Homo sapiens (related: human),,,,neutrophil,zinc-binding protein,,,,reduced virulence,,,,,,,,,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,29581188,PubMed,10.1128/IAI.00048-18,Infect Immun. 2018 May 22;86(6),y.ong@uq.edu.au,"The ΔczcD mutant and the ΔadcA ΔadcAII mutant were less virulent than 5448 GAS WT, with the ΔadcA ΔadcAII mutant showing the greatest attenuation of virulence.",C Y Ong 2018,2018,4 genes,Ong-2018-The role of zinc acquisition and zinc,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15305,PHI:9799,UniProt,Q9A0D2,,,,,,adcAII,,,,,,PHI:9798,1314,Streptococcus pyogenes,,5448,skin lesion,primates,9606,Homo sapiens (related: human),,,,neutrophil,zinc-binding protein,,,,reduced virulence,,,,,,,,,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,29581188,PubMed,10.1128/IAI.00048-18,Infect Immun. 2018 May 22;86(6),y.ong@uq.edu.au,"The ΔczcD mutant and the ΔadcA ΔadcAII mutant were less virulent than 5448 GAS WT, with the ΔadcA ΔadcAII mutant showing the greatest attenuation of virulence.",C Y Ong 2018,2018,4 genes,Ong-2018-The role of zinc acquisition and zinc,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15306,PHI:9800,UniProt,Q1JHF9,GenBank,ABF33777,,,MGAS10270,czcD,,,,,,,1314,Streptococcus pyogenes,,5448,skin lesion,primates,9606,Homo sapiens (related: human),,,,neutrophil,cobalt-zinc-cadmium resistance protein,,,,reduced virulence,,,,,,,,,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,29581188,PubMed,10.1128/IAI.00048-18,Infect Immun. 2018 May 22;86(6),y.ong@uq.edu.au,"The ΔczcD mutant and the ΔadcA ΔadcAII mutant were less virulent than 5448 GAS WT, with the ΔadcA ΔadcAII mutant showing the greatest attenuation of virulence.",C Y Ong 2018,2018,4 genes,Ong-2018-The role of zinc acquisition and zinc,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15307,PHI:9801,UniProt,Q675N6,GenBank,AAS09918,,,M1T1,sda1,,,,,,,1314,Streptococcus pyogenes,,5448,skin lesion,primates,9606,Homo sapiens (related: human),,,,neutrophil,phage-encoded extracellular streptodornase D,,,,reduced virulence,,,,,,,,,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,29581188,PubMed,10.1128/IAI.00048-18,Infect Immun. 2018 May 22;86(6),y.ong@uq.edu.au,"The ΔczcD mutant and the ΔadcA ΔadcAII mutant were less virulent than 5448 GAS WT, with the ΔadcA ΔadcAII mutant showing the greatest attenuation of virulence.",C Y Ong 2018,2018,4 genes,Ong-2018-The role of zinc acquisition and zinc,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15308,PHI:9798,UniProt,Q9A0L9,GenBank,AAK33667,,,SF370,adcA,,,,,,PHI:9799,1314,Streptococcus pyogenes,,5448,skin lesion,primates,9606,Homo sapiens (related: human),,,,serum,zinc-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,29581188,PubMed,10.1128/IAI.00048-18,Infect Immun. 2018 May 22;86(6),y.ong@uq.edu.au,"The ΔczcD mutant and the ΔadcA ΔadcAII mutant were less virulent than 5448 GAS WT, with the ΔadcA ΔadcAII mutant showing the greatest attenuation of virulence.",C Y Ong 2018,2018,4 genes,Ong-2018-The role of zinc acquisition and zinc,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15309,PHI:9799,UniProt,Q9A0D2,,,,,,adcAII,,,,,,PHI:9798,1314,Streptococcus pyogenes,,5448,skin lesion,primates,9606,Homo sapiens (related: human),,,,serum,zinc-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,29581188,PubMed,10.1128/IAI.00048-18,Infect Immun. 2018 May 22;86(6),y.ong@uq.edu.au,"The ΔczcD mutant and the ΔadcA ΔadcAII mutant were less virulent than 5448 GAS WT, with the ΔadcA ΔadcAII mutant showing the greatest attenuation of virulence.",C Y Ong 2018,2018,4 genes,Ong-2018-The role of zinc acquisition and zinc,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15310,PHI:9800,UniProt,Q1JHF9,GenBank,ABF33777,,,MGAS10270,czcD,,,,,,,1314,Streptococcus pyogenes,,5448,skin lesion,primates,9606,Homo sapiens (related: human),,,,serum,cobalt-zinc-cadmium resistance protein,,,,unaffected pathogenicity,,,,,,,,,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,29581188,PubMed,10.1128/IAI.00048-18,Infect Immun. 2018 May 22;86(6),y.ong@uq.edu.au,"The ΔczcD mutant and the ΔadcA ΔadcAII mutant were less virulent than 5448 GAS WT, with the ΔadcA ΔadcAII mutant showing the greatest attenuation of virulence.",C Y Ong 2018,2018,4 genes,Ong-2018-The role of zinc acquisition and zinc,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15311,PHI:9802,UniProt,A0A454XUZ2,GenBank,AE013779_9,,,KIM,PtsG,,,,,,,632,Yersinia pestis,214092,CO92,plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; blood,phosphotransferase system glucose transporter subunit IIBC,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29555700,PubMed,10.1128/JB.00737-17,J Bacteriol. 2018 May 9;200(11),jeremy.ritzert@northwestern.edu,"Y. pestis was responsible for depletion of glucose, likely by increasing the import of glucose dependent upon PtsG.",J T Ritzert 2018,2018,1 gene,Ritzert-2018-Depletion of Glucose Activates Ca,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15312,PHI:9803,UniProt,B3V1X9,GenBank,ACF17708,,,CM 2733,cyp51A,,"point mutations: F46Y, M172V, N248T, D255E, E427K",,,,,746128,Aspergillus fumigatus,,akuBKU80,aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,14-alpha sterol demethylase,,,,unaffected pathogenicity,,,,,,,,,,no,voriconazole,voriconazole: CHEBI:10023,,,,,gene deletion: full,,,YVS,29632011,PubMed,10.1128/AAC.00241-18,Antimicrob Agents Chemother. 2018 May 25;62(6),emellado@isciii.es,A. fumigatus strains with cyp51A SNPs at the time of diagnosis could influence the treatment response and outcomes of patients,R Garcia-Rubio 2018,2018,1 gene,Garcia-Rubio-2018-Aspergillus fumigatus cyp51A,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15313,PHI:9803,UniProt,B3V1X9,GenBank,ACF17708,,,CM 2733,cyp51A,,"point mutations: F46Y, M172V, N248T, D255E, E427K",,,,,746128,Aspergillus fumigatus,,akuBKU80,aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,14-alpha sterol demethylase,,,,unaffected pathogenicity,,,,,,,,,,no,voriconazole,voriconazole: CHEBI:10023,,,,,gene deletion: full,,,YVS,29632011,PubMed,10.1128/AAC.00241-18,Antimicrob Agents Chemother. 2018 May 25;62(6),emellado@isciii.es,A. fumigatus strains with cyp51A SNPs at the time of diagnosis could influence the treatment response and outcomes of patients,R Garcia-Rubio 2018,2018,1 gene,Garcia-Rubio-2018-Aspergillus fumigatus cyp51A,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15314,PHI:9804,UniProt,Q9X961,GenBank,CAB40914,,,KF 92,int,,,,,,PHI:9805,28901,Salmonella enterica,149539,subsp. enterica serovar Dublin strain PT4,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,small intestine; cecum; colon; blood; mesenteric lymph node; gall bladder; liver; spleen,integrase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31800631,PubMed,10.1371/journal.ppat.1008152,PLoS Pathog. 2019 Dec 4;15(12):e1008152,sbueno@bio.puc.cl,ROD21 excision by genes encoding for the integrase (int) and recombination directionality factor (RDF) was required to cross intestinal epithelial barrier and initiate colonization of internal organs.,C Pardo-Roa 2019,2019,4 genes,Pardo-Roa-2019-Pathogenicity island excision d,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15315,PHI:9805,UniProt,A0A6C7HRI3,GenBank,SEN1998,,,,rdf,,,,,,PHI:9804,28901,Salmonella enterica,149539,subsp. enterica serovar Dublin strain PT4,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,small intestine; cecum; colon; blood; mesenteric lymph node; gall bladder; liver; spleen,recombination directionality factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31800631,PubMed,10.1371/journal.ppat.1008152,PLoS Pathog. 2019 Dec 4;15(12):e1008152,sbueno@bio.puc.cl,ROD21 excision by genes encoding for the integrase (int) and recombination directionality factor (RDF) was required to cross intestinal epithelial barrier and initiate colonization of internal organs.,C Pardo-Roa 2019,2019,4 genes,Pardo-Roa-2019-Pathogenicity island excision d,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15316,PHI:9804,UniProt,Q9X961,GenBank,CAB40914,,,KF 92,int,,,,,,PHI:9806,28901,Salmonella enterica,149539,subsp. enterica serovar Dublin strain PT4,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,small intestine; cecum; colon; blood; mesenteric lymph node; gall bladder; liver; spleen,integrase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31800631,PubMed,10.1371/journal.ppat.1008152,PLoS Pathog. 2019 Dec 4;15(12):e1008152,sbueno@bio.puc.cl,ROD21 excision by genes encoding for the integrase (int) and recombination directionality factor (RDF) was required to cross intestinal epithelial barrier and initiate colonization of internal organs.,C Pardo-Roa 2019,2019,4 genes,Pardo-Roa-2019-Pathogenicity island excision d,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15317,PHI:9806,,no data found,,,,,,DRS,,,,,,PHI:9804,28901,Salmonella enterica,149539,subsp. enterica serovar Dublin strain PT4,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,small intestine; cecum; colon; blood; mesenteric lymph node; gall bladder; liver; spleen,direct repeated sequences,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31800631,PubMed,10.1371/journal.ppat.1008152,PLoS Pathog. 2019 Dec 4;15(12):e1008152,sbueno@bio.puc.cl,ROD21 excision by genes encoding for the integrase (int) and recombination directionality factor (RDF) was required to cross intestinal epithelial barrier and initiate colonization of internal organs.,C Pardo-Roa 2019,2019,4 genes,Pardo-Roa-2019-Pathogenicity island excision d,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15318,PHI:9807,,no data found,,,,,,ROD21,,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Dublin strain PT4,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,small intestine; cecum; colon; blood; mesenteric lymph node; gall bladder; liver; spleen,region of difference 21,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31800631,PubMed,10.1371/journal.ppat.1008152,PLoS Pathog. 2019 Dec 4;15(12):e1008152,sbueno@bio.puc.cl,Transfer of ROD21 improved the ability of S. Typhimurium to cause infection in mice.,C Pardo-Roa 2019,2019,4 genes,Pardo-Roa-2019-Pathogenicity island excision d,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15319,PHI:9807,,no data found,,,,,,ROD21,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; liver,region of difference 21,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: conjugation,,,YVS,31800631,PubMed,10.1371/journal.ppat.1008152,PLoS Pathog. 2019 Dec 4;15(12):e1008152,sbueno@bio.puc.cl,Transfer of ROD21 improved the ability of S. Typhimurium to cause infection in mice.,C Pardo-Roa 2019,2019,4 genes,Pardo-Roa-2019-Pathogenicity island excision d,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15320,PHI:9808,UniProt,P0CW86,GenBank,AAB62385,,,,SodCI,,,,,,PHI:9809,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),Perforin-2 KO 129 x 1/SvJ mice,,,spleen; liver,superoxide dismutase [Cu-Zn] 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30249808,PubMed,10.4049/jimmunol.1800365,J Immunol. 2018 Nov 1;201(9):2710-2720,gmunson@miami.edu,"Unlike the ΔsodCI sodCII+ strain that was killed by WT but not Perforin-2 KO phagocytes, the ΔsodCI sodCII::kan strain was killed by both Perforin-2 WT and KO phagocytes.",F Bai 2018,2018,2 genes,Bai-2018-Perforin-2 Breaches the Envelope of P,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15321,PHI:9809,UniProt,O68901,GenBank,AAC13559,,,14028s,SodCII,,,,,,PHI:9808,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),Perforin-2 KO 129 x 1/SvJ mice,,,spleen; liver,superoxide dismutase [Cu-Zn] 2,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30249808,PubMed,10.4049/jimmunol.1800365,J Immunol. 2018 Nov 1;201(9):2710-2720,gmunson@miami.edu,"Unlike the ΔsodCI sodCII+ strain that was killed by WT but not Perforin-2 KO phagocytes, the ΔsodCI sodCII::kan strain was killed by both Perforin-2 WT and KO phagocytes.",F Bai 2018,2018,2 genes,Bai-2018-Perforin-2 Breaches the Envelope of P,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15322,PHI:9808,UniProt,P0CW86,GenBank,AAB62385,,,,SodCI,,,,,,,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),Perforin-2 KO 129 x 1/SvJ mice,,,spleen; liver,superoxide dismutase [Cu-Zn] 1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30249808,PubMed,10.4049/jimmunol.1800365,J Immunol. 2018 Nov 1;201(9):2710-2720,gmunson@miami.edu,"Unlike the ΔsodCI sodCII+ strain that was killed by WT but not Perforin-2 KO phagocytes, the ΔsodCI sodCII::kan strain was killed by both Perforin-2 WT and KO phagocytes.",F Bai 2018,2018,2 genes,Bai-2018-Perforin-2 Breaches the Envelope of P,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15323,PHI:9808,UniProt,P0CW86,GenBank,AAB62385,,,,SodCI,,,,,,,28901,Salmonella enterica,99287,subsp. enterica serovar Typhimurium strain LT2,salmonellosis,rodents,10090,Mus musculus (related: house mouse),129X1/SvJ,,,spleen; liver,superoxide dismutase [Cu-Zn] 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30249808,PubMed,10.4049/jimmunol.1800365,J Immunol. 2018 Nov 1;201(9):2710-2720,gmunson@miami.edu,"Unlike the ΔsodCI sodCII+ strain that was killed by WT but not Perforin-2 KO phagocytes, the ΔsodCI sodCII::kan strain was killed by both Perforin-2 WT and KO phagocytes.",F Bai 2018,2018,2 genes,Bai-2018-Perforin-2 Breaches the Envelope of P,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15324,PHI:9810,UniProt,O50665,GenBank,AAC65998,,,B31,cspZ,,,,,,,139,Borreliella burgdorferi,,B31 A3,Lyme disease,primates,9606,Homo sapiens (related: human),,,,serum; blood,complement regulator-acquiring surface protein 2 (CRASP-2),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30571845,PubMed,10.1111/cmi.12998,Cell Microbiol. 2019 Feb;21(2):e12998,yi-pin.lin@health.ny.gov,Host gene alteration data available for C3 complement protein. Complement evasion mediated by CspZ–FH interactions facilitated blood-treated spirochete to survive in mouse bloodstream and tissues.,A L Marcinkiewicz 2018,2018,1 gene,Marcinkiewicz-2018-Blood treatment of Lyme bor,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15325,PHI:9810,UniProt,O50665,GenBank,AAC65998,,,B31,cspZ,,,,,,,139,Borreliella burgdorferi,,B31 A3,Lyme disease,birds,2567903,Coturnix coromandelica (related: rain quail),,,,serum,complement regulator-acquiring surface protein 2 (CRASP-2),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30571845,PubMed,10.1111/cmi.12998,Cell Microbiol. 2019 Feb;21(2):e12998,yi-pin.lin@health.ny.gov,Host gene alteration data available for C3 complement protein. Complement evasion mediated by CspZ–FH interactions facilitated blood-treated spirochete to survive in mouse bloodstream and tissues.,A L Marcinkiewicz 2018,2018,1 gene,Marcinkiewicz-2018-Blood treatment of Lyme bor,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15326,PHI:9810,UniProt,O50665,GenBank,AAC65998,,,B31,cspZ,,,,,,,139,Borreliella burgdorferi,,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; heart; bladder; joint,complement regulator-acquiring surface protein 2 (CRASP-2),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30571845,PubMed,10.1111/cmi.12998,Cell Microbiol. 2019 Feb;21(2):e12998,yi-pin.lin@health.ny.gov,Host gene alteration data available for C3 complement protein. Complement evasion mediated by CspZ–FH interactions facilitated blood-treated spirochete to survive in mouse bloodstream and tissues.,A L Marcinkiewicz 2018,2018,1 gene,Marcinkiewicz-2018-Blood treatment of Lyme bor,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15327,PHI:9811,UniProt,Q8RJQ0,GenBank,AAL78292,,,75-3,xopD,,,,,,,456327,Xanthomonas euvesicatoria,316273,Xe85-10,bacterial spot,eudicots,4081,Solanum lycopersicum (related: tomato),cv. VF36,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,salicylic acid; ethephon; methyl jasmonate,salicylic acid: CHEBI:16914; ethephon: CHEBI:52741; methyl jasmonate: CHEBI:15929,,,,,gene mutation,,,YVS,31322482,PubMed,10.1094/MPMI-05-19-0122-R,Mol Plant Microbe Interact. 2019 Dec;32(12):1614-1622,mudgett@stanford.edu,Host gene alteration data available for bHLH132. The non-TAL effector XopD strongly activated the transcription of bHLH132 in X. euvesicatoria–infected tomato leaves and bHLH132 was required and sufficient to protect tomato plants from X. euvesicatoria infection.,J G Kim 2019,2019,1 gene,Kim-2019-Tomato bHLH132 transcription factor c,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15328,PHI:9812,UniProt,Q9HWH1,GenBank,AAC64489,,,PAO1,phzA1,,,,,,PHI:9813,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),Kunming,,,lung; spleen; kidney; liver,phenazine biosynthesis protein,,,pyocyanin production,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31759864,PubMed,10.1016/j.ijmm.2019.151379,Int J Med Microbiol. 2019 Nov 11:151379,Kangmin.Duan@umanitoba.ca,"Disruption of the phzA1 and phzA2 eliminated the exacerbated pathogenicity in the co-infection group, indicating that the elevated pyocyanin production was the main contributing factor.",Q Peng 2019,2019,2 genes,Peng-2019-Co-existence of Citrobacter freundii,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15329,PHI:9813,UniProt,Q9I2J9,GenBank,AAD45624,,,UCBPP-PA14,phzA2,,,,,,PHI:9812,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),Kunming,,,lung; spleen; kidney; liver,phenazine biosynthesis protein,,,pyocyanin production,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31759864,PubMed,10.1016/j.ijmm.2019.151379,Int J Med Microbiol. 2019 Nov 11:151379,Kangmin.Duan@umanitoba.ca,"Disruption of the phzA1 and phzA2 eliminated the exacerbated pathogenicity in the co-infection group, indicating that the elevated pyocyanin production was the main contributing factor.",Q Peng 2019,2019,2 genes,Peng-2019-Co-existence of Citrobacter freundii,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15330,PHI:9814,UniProt,Q8XQW3,GenBank,CAD18256,,,GMI1000,otsA,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,stem,trehalose-6-phosphate synthase,,,trehalose biosynthetic pathway,reduced virulence,,,,,,,,wild type,,no,sodium chloride; polyethylene glycol; paraquat,sodium chloride: CHEBI:26710; polyethylene glycol: CHEBI:46793; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,31765286,PubMed,10.1094/MPMI-08-19-0218-R,Mol Plant Microbe Interact. 2019 Nov 25,cza@plantpath.wisc.edu,The lower colonization rates of the mutant strains and their significantly reduced competitive fitness indices suggested that Rs must synthesize trehalose to effectively colonize plants and cause disease.,A M MacIntyre 2019,2019,3 genes,MacIntyre-2019-Trehalose synthesis contributes,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15331,PHI:9815,UniProt,Q8XT80,GenBank,CAD17386,,,GMI1000,treY,,,,,,PHI:9816; PHI:9814,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,stem,trehalose synthase,,,trehalose biosynthetic pathway,reduced virulence,,,,,,,,wild type,,no,sodium chloride; polyethylene glycol; paraquat,sodium chloride: CHEBI:26710; polyethylene glycol: CHEBI:46793; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,31765286,PubMed,10.1094/MPMI-08-19-0218-R,Mol Plant Microbe Interact. 2019 Nov 25,cza@plantpath.wisc.edu,The lower colonization rates of the mutant strains and their significantly reduced competitive fitness indices suggested that Rs must synthesize trehalose to effectively colonize plants and cause disease.,A M MacIntyre 2019,2019,3 genes,MacIntyre-2019-Trehalose synthesis contributes,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15332,PHI:9816,UniProt,A0A0S4VR07,GenBank,CUV36794,,,Phyl III-seqv23,treS,chromosome 7,,,,,PHI:9815; PHI:9814,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,stem,trehalose synthase,,,trehalose biosynthetic pathway,reduced virulence,,,,,,,,wild type,,no,sodium chloride; polyethylene glycol; paraquat,sodium chloride: CHEBI:26710; polyethylene glycol: CHEBI:46793; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,31765286,PubMed,10.1094/MPMI-08-19-0218-R,Mol Plant Microbe Interact. 2019 Nov 25,cza@plantpath.wisc.edu,The lower colonization rates of the mutant strains and their significantly reduced competitive fitness indices suggested that Rs must synthesize trehalose to effectively colonize plants and cause disease.,A M MacIntyre 2019,2019,3 genes,MacIntyre-2019-Trehalose synthesis contributes,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15333,PHI:9814,UniProt,Q8XQW3,GenBank,CAD18256,,,GMI1000,otsA,,,,,,PHI:9815; PHI:9816,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,stem,trehalose-6-phosphate synthase,,,trehalose biosynthetic pathway,reduced virulence,,,,,,,,wild type,,no,sodium chloride; polyethylene glycol; paraquat,sodium chloride: CHEBI:26710; polyethylene glycol: CHEBI:46793; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,31765286,PubMed,10.1094/MPMI-08-19-0218-R,Mol Plant Microbe Interact. 2019 Nov 25,cza@plantpath.wisc.edu,The lower colonization rates of the mutant strains and their significantly reduced competitive fitness indices suggested that Rs must synthesize trehalose to effectively colonize plants and cause disease.,A M MacIntyre 2019,2019,3 genes,MacIntyre-2019-Trehalose synthesis contributes,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15334,PHI:9817,UniProt,P0DJM0,GenBank,CAC20628,,,EGD,inlA (lmo0433),,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29715536,PubMed,10.1016/j.micpath.2018.04.059,Microb Pathog. 2018 Jul;120:79-84,liuq@usst.edu.cn,"Compared with EGD-e, mutant strains showed significantly decreased invasion and apoptosis, however, mutant strains were capable to evoke cytokines transcription of IL-8, MCP-1, TNF-a, IL-1β, IL-6 and CXCL-2 production in Caco-2 cells.",M Xie 2018,2018,5 genes,Xie-2018-Evaluation of Caco-2cells response to,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15335,PHI:9818,UniProt,P0DQD2,GenBank,CAC98513,,,EGD-e,inlB (lmo0434),,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,internalin B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29715536,PubMed,10.1016/j.micpath.2018.04.059,Microb Pathog. 2018 Jul;120:79-84,liuq@usst.edu.cn,"Compared with EGD-e, mutant strains showed significantly decreased invasion and apoptosis, however, mutant strains were capable to evoke cytokines transcription of IL-8, MCP-1, TNF-a, IL-1β, IL-6 and CXCL-2 production in Caco-2 cells.",M Xie 2018,2018,5 genes,Xie-2018-Evaluation of Caco-2cells response to,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15336,PHI:9819,UniProt,P13128,GenBank,CAA33223,,,EGD serotype 1/2 a,hly (lmo0202),,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,listeriolysin O,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29715536,PubMed,10.1016/j.micpath.2018.04.059,Microb Pathog. 2018 Jul;120:79-84,liuq@usst.edu.cn,"Compared with EGD-e, mutant strains showed significantly decreased invasion and apoptosis, however, mutant strains were capable to evoke cytokines transcription of IL-8, MCP-1, TNF-a, IL-1β, IL-6 and CXCL-2 production in Caco-2 cells.",M Xie 2018,2018,5 genes,Xie-2018-Evaluation of Caco-2cells response to,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15337,PHI:9820,UniProt,P33379,GenBank,AAA25269,,,L028,actA (lmo0204),,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,actin assembly-inducing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29715536,PubMed,10.1016/j.micpath.2018.04.059,Microb Pathog. 2018 Jul;120:79-84,liuq@usst.edu.cn,"Compared with EGD-e, mutant strains showed significantly decreased invasion and apoptosis, however, mutant strains were capable to evoke cytokines transcription of IL-8, MCP-1, TNF-a, IL-1β, IL-6 and CXCL-2 production in Caco-2 cells.",M Xie 2018,2018,5 genes,Xie-2018-Evaluation of Caco-2cells response to,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15338,PHI:9821,UniProt,Q8Y4A8,GenBank,CAD00621,,,EGD-e,prfA (lmo2543),,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,peptide chain release factor 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29715536,PubMed,10.1016/j.micpath.2018.04.059,Microb Pathog. 2018 Jul;120:79-84,liuq@usst.edu.cn,"Compared with EGD-e, mutant strains showed significantly decreased invasion and apoptosis, however, mutant strains were capable to evoke cytokines transcription of IL-8, MCP-1, TNF-a, IL-1β, IL-6 and CXCL-2 production in Caco-2 cells.",M Xie 2018,2018,5 genes,Xie-2018-Evaluation of Caco-2cells response to,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15339,PHI:9822,UniProt,I1RAY2,GenBank,CEF72653,,,PH-1,Fg00677,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),Bd21-3 line,,,spikelet,protein kinase domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,31737001,PubMed,10.3389/fpls.2019.01362,Front Plant Sci. 2019 Oct 30;10:1362,guojunwgq@nwsuaf.edu.cn,"Fg00677-RNAi, Fg08731-RNAi and CYP51RNAi transgenic lines exhibited strong resistance to F. graminearum, suggesting that silencing molecules produced by transgenic plants reduced pathogenicity.",F He 2019,2019,5 genes,He-2019-Host-Induced Silencing of Fusarium gra,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15340,PHI:9823,UniProt,A0A0E0S0W9,GenBank,CEF77144,,,PH-1,Fg08731,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),Bd21-3 line,,,spikelet,protein kinase domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,31737001,PubMed,10.3389/fpls.2019.01362,Front Plant Sci. 2019 Oct 30;10:1362,guojunwgq@nwsuaf.edu.cn,"Fg00677-RNAi, Fg08731-RNAi and CYP51RNAi transgenic lines exhibited strong resistance to F. graminearum, suggesting that silencing molecules produced by transgenic plants reduced pathogenicity.",F He 2019,2019,5 genes,He-2019-Host-Induced Silencing of Fusarium gra,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15341,PHI:9824,UniProt,I6YDU0,GenBank,AFN66169,,,,CYP51A,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),Bd21-3 line,,,spikelet,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,31737001,PubMed,10.3389/fpls.2019.01362,Front Plant Sci. 2019 Oct 30;10:1362,guojunwgq@nwsuaf.edu.cn,"Fg00677-RNAi, Fg08731-RNAi and CYP51RNAi transgenic lines exhibited strong resistance to F. graminearum, suggesting that silencing molecules produced by transgenic plants reduced pathogenicity.",F He 2019,2019,5 genes,He-2019-Host-Induced Silencing of Fusarium gra,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15342,PHI:9825,UniProt,I1RBR4,GenBank,CEF73055,,,PH-1,CYP51B,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),Bd21-3 line,,,spikelet,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,31737001,PubMed,10.3389/fpls.2019.01362,Front Plant Sci. 2019 Oct 30;10:1362,guojunwgq@nwsuaf.edu.cn,"Fg00677-RNAi, Fg08731-RNAi and CYP51RNAi transgenic lines exhibited strong resistance to F. graminearum, suggesting that silencing molecules produced by transgenic plants reduced pathogenicity.",F He 2019,2019,5 genes,He-2019-Host-Induced Silencing of Fusarium gra,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15343,PHI:9826,UniProt,L7WLT2,GenBank,AGC81882,,,,CYP51C,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),Bd21-3 line,,,spikelet,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,31737001,PubMed,10.3389/fpls.2019.01362,Front Plant Sci. 2019 Oct 30;10:1362,guojunwgq@nwsuaf.edu.cn,"Fg00677-RNAi, Fg08731-RNAi and CYP51RNAi transgenic lines exhibited strong resistance to F. graminearum, suggesting that silencing molecules produced by transgenic plants reduced pathogenicity.",F He 2019,2019,5 genes,He-2019-Host-Induced Silencing of Fusarium gra,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15344,PHI:9827,UniProt,O53340,GenBank,CCP46006,,,H37Rv,rv3194c,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,heterologous expression,,,YVS,31731061,PubMed,10.1016/j.tube.2019.101880,Tuberculosis (Edinb). 2019 Dec,liusiguo@caas.cn,"In mice, Rv3194c enhanced the persistence of Mycobacterium smegmatis (Ms) in the lung, induced lung lesions, and promoted the release of inflammatory cytokines.",H Li 2019,2019,1 gene,Li-2019-Characterization of a novel Mycobacter,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15345,PHI:9827,UniProt,O53340,GenBank,CCP46006,,,H37Rv,rv3194c,,D308A/ S309A,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; heterologous expression,,,YVS,31731061,PubMed,10.1016/j.tube.2019.101880,Tuberculosis (Edinb). 2019 Dec,liusiguo@caas.cn,"In mice, Rv3194c enhanced the persistence of Mycobacterium smegmatis (Ms) in the lung, induced lung lesions, and promoted the release of inflammatory cytokines.",H Li 2019,2019,1 gene,Li-2019-Characterization of a novel Mycobacter,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15346,PHI:9827,UniProt,O53340,GenBank,CCP46006,,,H37Rv,rv3194c,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,heterologous expression,,,YVS,31731061,PubMed,10.1016/j.tube.2019.101880,Tuberculosis (Edinb). 2019 Dec,liusiguo@caas.cn,"Rv3194c inhibited THP1-derived macrophage migration, degraded the complement components, C3b and C5a, causing inhibition of phagocytosis and chemotaxis.",H Li 2019,2019,1 gene,Li-2019-Characterization of a novel Mycobacter,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15347,PHI:9827,UniProt,O53340,GenBank,CCP46006,,,H37Rv,rv3194c,,D308A/ S309A,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; heterologous expression,,,YVS,31731061,PubMed,10.1016/j.tube.2019.101880,Tuberculosis (Edinb). 2019 Dec,liusiguo@caas.cn,"Rv3194c inhibited THP1-derived macrophage migration, degraded the complement components, C3b and C5a, causing inhibition of phagocytosis and chemotaxis.",H Li 2019,2019,1 gene,Li-2019-Characterization of a novel Mycobacter,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15348,PHI:9828,UniProt,Q8DRI0,GenBank,VTI81216,,,GPSC81,PspA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,pneumococcal surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30323030,PubMed,10.1128/IAI.00742-18,Infect Immun. 2018 Dec 19;87(1). pii: e00742-18,njlynch67@gmail.com,PspA and PspC helped the pneumococcus to evade complement attack by binding C4BP and so inactivating C4b.,K S Haleem 2018,2018,2 genes,Haleem-2018-The pneumococcal surface proteins,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15349,PHI:9829,UniProt,Q9KK37,GenBank,AAF73791,,,g389,PspC,,,,,,,1313,Streptococcus pneumoniae,373154,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,pneumococcal surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30323030,PubMed,10.1128/IAI.00742-18,Infect Immun. 2018 Dec 19;87(1). pii: e00742-18,njlynch67@gmail.com,PspA and PspC helped the pneumococcus to evade complement attack by binding C4BP and so inactivating C4b.,K S Haleem 2018,2018,2 genes,Haleem-2018-The pneumococcal surface proteins,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15350,PHI:9828,UniProt,Q8DRI0,GenBank,VTI81216,,,GPSC81,PspA,,,,,,PHI:9829,1313,Streptococcus pneumoniae,373155,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,pneumococcal surface protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30323030,PubMed,10.1128/IAI.00742-18,Infect Immun. 2018 Dec 19;87(1). pii: e00742-18,njlynch67@gmail.com,PspA and PspC helped the pneumococcus to evade complement attack by binding C4BP and so inactivating C4b.,K S Haleem 2018,2018,2 genes,Haleem-2018-The pneumococcal surface proteins,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15351,PHI:9829,UniProt,Q9KK37,GenBank,AAF73791,,,g389,PspC,,,,,,PHI:9828,1313,Streptococcus pneumoniae,373156,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,pneumococcal surface protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30323030,PubMed,10.1128/IAI.00742-18,Infect Immun. 2018 Dec 19;87(1). pii: e00742-18,njlynch67@gmail.com,PspA and PspC helped the pneumococcus to evade complement attack by binding C4BP and so inactivating C4b.,K S Haleem 2018,2018,2 genes,Haleem-2018-The pneumococcal surface proteins,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15352,PHI:9830,,no data found,,,,,,bstA,,,,,,,28901,Salmonella enterica,909945,subsp. enterica serovar Dublin strain SD3246,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,uncharacterized protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29109173,PubMed,10.1128/IAI.00784-17,Infect Immun. 2017 Dec 19;86(1). pii: e00784-17,ahefr@sund.ku.dk,S. Dublin ΔbstA showed higher levels of uptake than the wild-type strain during infection of mouse and cattle macrophages and higher net replication within human THP-1 cells.,A Herrero-Fresno 2017,2017,2 genes,Herrero-Fresno-2017-The homolog of the gene bs,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15353,PHI:9830,,no data found,,,,,,bstA,,,,,,,28901,Salmonella enterica,909945,subsp. enterica serovar Dublin strain SD3246,salmonellosis,even-toed ungulates,9913,Bos taurus (related: cattle),BoMac cell line,,,macrophage,uncharacterized protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29109173,PubMed,10.1128/IAI.00784-17,Infect Immun. 2017 Dec 19;86(1). pii: e00784-17,ahefr@sund.ku.dk,S. Dublin ΔbstA showed higher levels of uptake than the wild-type strain during infection of mouse and cattle macrophages and higher net replication within human THP-1 cells.,A Herrero-Fresno 2017,2017,2 genes,Herrero-Fresno-2017-The homolog of the gene bs,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15354,PHI:9830,,no data found,,,,,,bstA,,,,,,,28901,Salmonella enterica,909945,subsp. enterica serovar Dublin strain SD3246,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,uncharacterized protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29109173,PubMed,10.1128/IAI.00784-17,Infect Immun. 2017 Dec 19;86(1). pii: e00784-17,ahefr@sund.ku.dk,S. Dublin ΔbstA showed higher levels of uptake than the wild-type strain during infection of mouse and cattle macrophages and higher net replication within human THP-1 cells.,A Herrero-Fresno 2017,2017,2 genes,Herrero-Fresno-2017-The homolog of the gene bs,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15355,PHI:9830,,no data found,,,,,,bstA,,,,,,,28901,Salmonella enterica,909945,subsp. enterica serovar Dublin strain SD3246,salmonellosis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,intestinal epithelium,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29109173,PubMed,10.1128/IAI.00784-17,Infect Immun. 2017 Dec 19;86(1). pii: e00784-17,ahefr@sund.ku.dk,Deletion of the bstA gene did not affect S. Dublin adhesion to or invasion of cells of human epithelial cell line Int-407.,A Herrero-Fresno 2017,2017,2 genes,Herrero-Fresno-2017-The homolog of the gene bs,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15356,PHI:9830,,no data found,,,,,,bstA,,,,,,,28901,Salmonella enterica,909945,subsp. enterica serovar Dublin strain SD3246,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node,uncharacterized protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29109173,PubMed,10.1128/IAI.00784-17,Infect Immun. 2017 Dec 19;86(1). pii: e00784-17,ahefr@sund.ku.dk,S. Dublin ΔbstA showed higher levels of uptake than the wild-type strain during infection of mouse and cattle macrophages and higher net replication within human THP-1 cells.,A Herrero-Fresno 2017,2017,2 genes,Herrero-Fresno-2017-The homolog of the gene bs,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15357,PHI:9831,UniProt,D0ZWU0,GenBank,ACY88188,,,14028S,ssaV,,,,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,secretion system apparatus protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29109173,PubMed,10.1128/IAI.00784-17,Infect Immun. 2017 Dec 19;86(1). pii: e00784-17,ahefr@sund.ku.dk,The strain S. Typhimurium 4/74 ΔssaV showed a significant decrease in net replication compared to that of the WT 4/74 strain.,A Herrero-Fresno 2017,2017,2 genes,Herrero-Fresno-2017-The homolog of the gene bs,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15358,PHI:9832,UniProt,D0ZWU0,GenBank,ACY88188,,,14028S,ssaV,,,,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,even-toed ungulates,9913,Bos taurus (related: cattle),BoMac cell line,,,macrophage,secretion system apparatus protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29109173,PubMed,10.1128/IAI.00784-17,Infect Immun. 2017 Dec 19;86(1). pii: e00784-17,ahefr@sund.ku.dk,The strain S. Typhimurium 4/74 ΔssaV showed a significant decrease in net replication compared to that of the WT 4/74 strain.,A Herrero-Fresno 2017,2017,2 genes,Herrero-Fresno-2017-The homolog of the gene bs,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15359,PHI:9833,UniProt,D0ZWU0,GenBank,ACY88188,,,14028S,ssaV,,,,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,secretion system apparatus protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29109173,PubMed,10.1128/IAI.00784-17,Infect Immun. 2017 Dec 19;86(1). pii: e00784-17,ahefr@sund.ku.dk,The strain S. Typhimurium 4/74 ΔssaV showed a significant decrease in net replication compared to that of the WT 4/74 strain.,A Herrero-Fresno 2017,2017,2 genes,Herrero-Fresno-2017-The homolog of the gene bs,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15360,PHI:9832,UniProt,E9AVK8,GenBank,CBZ26991,,,MHOM/GT/2001/U1103,LmDUSP1 (LmxM.22.0250),,,,,,,5665,Leishmania mexicana,,MNYC/BZ/62/M379,leishmaniasis,flies,7200,Lutzomyia longipalpis (no common name found),,,,midgut,dual specificity protein/lipid phosphatase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31744234,PubMed,10.3390/pathogens8040241,Pathogens. 2019 Nov 17;8(4). pii: E241,vyacheslav.yurchenko@osu.cz,"Despite significant upregulation of LmxM.22.0250 expression in metacyclic promastigotes, its ablation did not affect the ability of mutant cells to differentiate into virulent stages in insects.",N Kraeva 2019,2019,1 gene,Kraeva-2019-LmxM.22.0250-Encoded Dual Specific,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15361,PHI:9832,UniProt,E9AVK8,GenBank,CBZ26991,,,MHOM/GT/2001/U1103,LmDUSP1 (LmxM.22.0250),,,,,,,5665,Leishmania mexicana,,MNYC/BZ/62/M379,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,macrophage,dual specificity protein/lipid phosphatase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31744234,PubMed,10.3390/pathogens8040241,Pathogens. 2019 Nov 17;8(4). pii: E241,vyacheslav.yurchenko@osu.cz,"Despite significant upregulation of LmxM.22.0250 expression in metacyclic promastigotes, its ablation did not affect the ability of mutant cells to differentiate into virulent stages in insects. Macrophages ears",N Kraeva 2019,2019,1 gene,Kraeva-2019-LmxM.22.0250-Encoded Dual Specific,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15362,PHI:9833,UniProt,Q8PBY5,GenBank,AAM40281,,,ATCC 33913,clpX,,,,,,,339,Xanthomonas campestris,,pv. campestris strain Xc17,black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,ATP-binding subunit of ATP-dependent Clp protease,,,,reduced virulence,,,,,,,,wild type,,no,hydrogen peroxide; polymyxin B; puromycin; sodium dodecyl sulfate,"hydrogen peroxide: CHEBI:16240; polymyxin B: CHEBI:8309; puromycin 17939,  sodium dodecyl sulfate (SDS): CHEBI:8984",,,,,gene mutation; gene complementation,,,YVS,31741013,PubMed,10.1007/s00203-019-01772-3,Arch Microbiol. 2019 Nov 19,ymhsiao@ctust.edu.tw,"The clpX mutant exhibited reduced bacterial attachment, extracellular enzyme production and virulence.",H H Lo 2019,2019,1 gene,Lo-2019-The clpX gene plays an important role,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15363,PHI:9834,UniProt,A0A384JD01,GenBank,ATZ48466,,,B05.10,bcnoxR,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,regulatory subunit of NOX,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide,hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31230563,PubMed,10.1094/MPMI-05-19-0124-R,Mol Plant Microbe Interact. 2019 Nov;32(11):1508-1516,gzqin@ibcas.ac.cn,BcNoxR was essential for maintaining the equilibrium of the redox state in B. cinerea.,H Li 2019,2019,2 genes,Li-2019-NADPH oxidase is crucial for the cellu,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15364,PHI:9835,UniProt,A0A384JMC8,GenBank,ATZ51660,,,B05.10,bcpgd,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,6-phosphogluconate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide,hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31230563,PubMed,10.1094/MPMI-05-19-0124-R,Mol Plant Microbe Interact. 2019 Nov;32(11):1508-1516,gzqin@ibcas.ac.cn,"BcNoxR regulated the oxidative stress response and pathogenesis, at least partially, by affecting the oxidation state of BcPGD.",H Li 2019,2019,2 genes,Li-2019-NADPH oxidase is crucial for the cellu,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15365,PHI:9836,UniProt,Q9A0F1,GenBank,AAK33739,,,SF370,ess (SPy_0802),,,,,,,1314,Streptococcus pyogenes,,serotype M1 strain 5448,systemic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; spleen,S protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31801066,PubMed,10.1016/j.celrep.2019.11.001,Cell Rep. 2019 Dec 3;29(10):2979-2989.e15,djgonzalez@ucsd.edu,"Invivo, the absence of S protein resulted in attenuation of virulence and promoted a robust immune response and immunological memory.",I H Wierzbicki 2019,2019,1 gene,Wierzbicki-2019-Group A Streptococcal S Protei,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15366,PHI:9836,UniProt,Q9A0F1,GenBank,AAK33739,,,SF370,ess (SPy_0802),,,,,,,1314,Streptococcus pyogenes,,serotype M1 strain 5448,systemic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (Ifnar<-/->),,,,S protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31801066,PubMed,10.1016/j.celrep.2019.11.001,Cell Rep. 2019 Dec 3;29(10):2979-2989.e15,djgonzalez@ucsd.edu,"Invivo, the absence of S protein resulted in attenuation of virulence and promoted a robust immune response and immunological memory.",I H Wierzbicki 2019,2019,1 gene,Wierzbicki-2019-Group A Streptococcal S Protei,BATCH_098B,2020-01-01,MC,,,,,,,,,,,,,
,,Record 15367,PHI:9837,UniProt,A0A2R8EF82,GenBank,AWB75295,,,A1552,CrbS,,crbSΔSTAC,,,,,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15368,PHI:9838,UniProt,A0A085PGU8,GenBank,CPR25558,,,V. cholerae 116-17a,acs,,,,,,PHI:9837,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15369,PHI:9837,UniProt,A0A2R8EF82,GenBank,AWB75295,,,A1552,CrbS,,crbSΔSTAC,,,,PHI:9838,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15370,PHI:9837,UniProt,A0A2R8EF82,GenBank,AWB75295,,,A1552,CrbS,,mutations in the putative CrbS Na+ binding site (S337A/T338V),,,,,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15371,PHI:9837,UniProt,A0A2R8EF82,GenBank,AWB75295,,,A1552,CrbS,,"excision of entire transporter domain coding sequence, including codons for amino acids 4 to 504",,,,,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15372,PHI:9837,UniProt,A0A2R8EF82,GenBank,AWB75295,,,A1552,CrbS,,,,,,,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15373,PHI:9838,UniProt,A0A085PGU8,GenBank,CPR25558,,,V. cholerae 116-17a,acs,,,,,,,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15374,PHI:9839,UniProt,O34015,GenBank,AAC45784,,,O395,crp,,,,,,,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,cyclic AMP receptor protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15375,PHI:9840,UniProt,Q9KVL9,GenBank,AAF93300,,,N16961,cya,chromosome I,,,,,,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,adenylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15376,PHI:9841,UniProt,O51804,GenBank,AAC38175,,,92A1552,rpoS,,,,,,,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15377,PHI:9842,UniProt,Q9KT08,GenBank,AAF94256,,,N16961,pta,,,,,,,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,phosphate acetyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15378,PHI:9843,UniProt,A0A0H3Q0Y8,GenBank,EEO15930,,,B33,ackA,,,,,,,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,acetate kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15379,PHI:9842,UniProt,Q9KT08,GenBank,AAF94256,,,N16961,pta,,,,,,PHI:9843,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,phosphate acetyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15380,PHI:9843,UniProt,A0A0H3Q0Y8,GenBank,EEO15930,,,B33,ackA,,,,,,PHI:9842,666,Vibrio cholerae,,SIO,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,gastrointestinal tract,acetate kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30224439,PubMed,10.1128/JB.00380-18,J Bacteriol. 2018 Nov 6;200(23),apurdy@amherst.edu,Information funneled through CrbS is detectable to the bacterium only at times when preferred carbon sources are absent and that the environment may affect CrbS-dependent signaling mechanisms.,I Muzhingi 2018,2018,7 genes,Muzhingi-2018-Modulation of CrbS-dependent act,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15381,PHI:9844,UniProt,I6XER9,GenBank,CCP45415,,,H37Rv,Rv2617c,,,,,,,1773,Mycobacterium tuberculosis,,CDC 1551,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,integral membrane protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31782338,PubMed,10.1080/21505594.2019.1693714,Virulence. 2019 Dec;10(1):1026-1033,bigi.fabiana@inta.gob.ar,Knockout of the Rv2617c gene in M. tuberculosis CDC1551 reduced the replication of the pathogen in a mouse model of infection and favored the trafficking of mycobacteria to phagolysosomes.,M A Forrellad 2019,2019,1 gene,Forrellad-2019-Rv2617c and P36 are virulence f,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15382,PHI:9844,UniProt,I6XER9,GenBank,CCP45415,,,H37Rv,Rv2617c,,,,,,,1773,Mycobacterium tuberculosis,,CDC 1551,tuberculosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,integral membrane protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31782338,PubMed,10.1080/21505594.2019.1693714,Virulence. 2019 Dec;10(1):1026-1033,bigi.fabiana@inta.gob.ar,The lack of Rv2617c impaired the modulation of phagosomal maturation induced by M. tuberculosis inside murine macrophages.,M A Forrellad 2019,2019,1 gene,Forrellad-2019-Rv2617c and P36 are virulence f,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15383,PHI:9845,UniProt,I1RBZ5,GenBank,XP_011316857,,,PH-1; NRRL 31084,FgEaf6 (FGSG-01094.1),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Qingmai 6,,,inflorescence; coleoptile,hypothetical protein,,,,reduced virulence,,,,,,reduced; aberrant,reduced; aberrant,reduced; aberrant,,no,H2O2; NaCl; sodium dodecyl sulfate; Congo red,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulfate: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31728616,PubMed,10.1007/s00294-019-01043-0,Curr Genet. 2019 Nov 14,zhoushanyao@126.com,"ΔFgEaf6 mutant exhibited manifold defects in hyphal growth, conidial septation, asexual and sexual reproduction.",J Qin 2019,2019,1 gene,"Qin-2019-FgEaf6 regulates virulence, asexual_s",BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15384,PHI:9846,UniProt,A0A226BSF5,GenBank,OWZ81264,,,Bt85,Yap1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung; liver; spleen; kidney,bZip domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; diamide; tert-butyl hydroperoxide; menadione; calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; CdSO4; fluconazole; amphotericin B; fludioxonil; flucytosine,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; menadione: CHEBI:28869; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; CdSO4: CHEBI:50292; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; fludioxonil: CHEBI:81763; flucytosine: CHEBI:5100,,,,,gene mutation; gene complementation,,,YVS,31748248,PubMed,10.1128/mSphere.00785-19,mSphere. 2019 Nov 20;4(6),ysbahn@yonsei.ac.kr.,"Yap1 played a minor role in C. neoformans virulence, whereas Atf1 was mostly dispensable.",Y So 2019,2019,2 genes,So-2019-Regulatory Mechanism of the Atypical A,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15385,PHI:9847,,no data found,,,,,,atf1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung; liver; spleen; kidney,basic leucine zipper (bZip) protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; diamide; tert-butyl hydroperoxide; menadione; calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; CdSO4; fluconazole; amphotericin B; fludioxonil; flucytosine,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; menadione: CHEBI:28869; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; CdSO4: CHEBI:50292; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; fludioxonil: CHEBI:81763; flucytosine: CHEBI:5100,,,,,gene mutation,,,YVS,31748248,PubMed,10.1128/mSphere.00785-19,mSphere. 2019 Nov 20;4(6),ysbahn@yonsei.ac.kr.,"Yap1 played a minor role in C. neoformans virulence, whereas Atf1 was mostly dispensable.",Y So 2019,2019,2 genes,So-2019-Regulatory Mechanism of the Atypical A,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15386,PHI:9847,,no data found,,,,,,atf1,,,,,,PHI:9846,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung; liver; spleen; kidney,basic leucine zipper (bZip) protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; diamide; tert-butyl hydroperoxide; menadione; calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; CdSO4; fluconazole; amphotericin B; fludioxonil; flucytosine,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; menadione: CHEBI:28869; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; CdSO4: CHEBI:50292; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; fludioxonil: CHEBI:81763; flucytosine: CHEBI:5100,,,,,gene mutation,,,YVS,31748248,PubMed,10.1128/mSphere.00785-19,mSphere. 2019 Nov 20;4(6),ysbahn@yonsei.ac.kr.,"Yap1 played a minor role in C. neoformans virulence, whereas Atf1 was mostly dispensable.",Y So 2019,2019,2 genes,So-2019-Regulatory Mechanism of the Atypical A,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15387,PHI:9846,UniProt,A0A226BSF5,GenBank,OWZ81264,,,Bt85,Yap1,,,,,,PHI:9847,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung; liver; spleen; kidney,bZip domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; diamide; tert-butyl hydroperoxide; menadione; calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; CdSO4; fluconazole; amphotericin B; fludioxonil; flucytosine,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; menadione: CHEBI:28869; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; CdSO4: CHEBI:50292; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; fludioxonil: CHEBI:81763; flucytosine: CHEBI:5100,,,,,gene mutation; gene complementation,,,YVS,31748248,PubMed,10.1128/mSphere.00785-19,mSphere. 2019 Nov 20;4(6),ysbahn@yonsei.ac.kr.,"Yap1 played a minor role in C. neoformans virulence, whereas Atf1 was mostly dispensable.",Y So 2019,2019,2 genes,So-2019-Regulatory Mechanism of the Atypical A,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15388,PHI:9846,UniProt,A0A226BSF5,GenBank,OWZ81264,,,Bt85,Yap1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/J,,,brain; lung,bZip domain-containing protein,,,,reduced virulence,,,,,,,,,,no,H2O2; diamide; tert-butyl hydroperoxide; menadione; calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; CdSO4; fluconazole; amphotericin B; fludioxonil; flucytosine,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; menadione: CHEBI:28869; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; CdSO4: CHEBI:50292; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; fludioxonil: CHEBI:81763; flucytosine: CHEBI:5100,,,,,gene mutation; gene complementation,,,YVS,31748248,PubMed,10.1128/mSphere.00785-19,mSphere. 2019 Nov 20;4(6),ysbahn@yonsei.ac.kr.,"The yap1 Δ mutant showed weakly reduced virulence in an A/J mouse model but normal virulence in a BALB/c mouse model, indicating that the role of Yap1 in C. neoformans virulence may depend on host systems.",Y So 2019,2019,2 genes,So-2019-Regulatory Mechanism of the Atypical A,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15389,PHI:9847,,no data found,,,,,,atf1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/J,,,brain; lung,basic leucine zipper (bZip) protein,,,,reduced virulence,,,,,,,,,,no,H2O2; diamide; tert-butyl hydroperoxide; menadione; calcofluor white; Congo red; SDS; NaCl; KCl; sorbitol; CdSO4; fluconazole; amphotericin B; fludioxonil; flucytosine,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; menadione: CHEBI:28869; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; CdSO4: CHEBI:50292; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; fludioxonil: CHEBI:81763; flucytosine: CHEBI:5100,,,,,gene mutation,,,YVS,31748248,PubMed,10.1128/mSphere.00785-19,mSphere. 2019 Nov 20;4(6),ysbahn@yonsei.ac.kr.,"The yap1 Δ mutant showed weakly reduced virulence in an A/J mouse model but normal virulence in a BALB/c mouse model, indicating that the role of Yap1 in C. neoformans virulence may depend on host systems.",Y So 2019,2019,2 genes,So-2019-Regulatory Mechanism of the Atypical A,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15390,PHI:9848,UniProt,J9VMK1,GenBank,AFR93834,,,H99,ali1 (CNAG_02857),chromosome 3,,,,,,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,arrestin_C domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15391,PHI:9848,UniProt,J9VMK1,GenBank,AFR93834,,,H99,ali1 (CNAG_02857),chromosome 3,,,,,,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,arrestin_C domain-containing protein,,,,reduced virulence,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15392,PHI:9849,UniProt,J9VMM3,GenBank,AFR95488,,,H99,ali2 (CNAG_02341),chromosome 6,,,,,,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,cyclin binding protein,,,,reduced virulence,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15393,PHI:9850,UniProt,J9VQX7,GenBank,AFR96867,,,H99,ali3 (CNAG_04137),chromosome 9,,,,,,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,arrestin_C domain-containing protein,,,,reduced virulence,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15394,PHI:9851,UniProt,J9VWA9,GenBank,AFR98767,,,H99,ali4 (CNAG_05343),chromosome 14,,,,,,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,arrestin_C domain-containing protein,,,,reduced virulence,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15395,PHI:9848,UniProt,J9VMK1,GenBank,AFR93834,,,H99,ali1 (CNAG_02857),chromosome 3,,,,,PHI:9849,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,arrestin_C domain-containing protein,,,,reduced virulence,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15396,PHI:9849,UniProt,J9VMM3,GenBank,AFR95488,,,H99,ali2 (CNAG_02341),chromosome 6,,,,,PHI:9848,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,cyclin binding protein,,,,reduced virulence,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15397,PHI:9848,UniProt,J9VMK1,GenBank,AFR93834,,,H99,ali1 (CNAG_02857),chromosome 3,,,,,PHI:9849; PHI:9850; PHI:9851,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,arrestin_C domain-containing protein,,,,reduced virulence,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15398,PHI:9849,UniProt,J9VMM3,GenBank,AFR95488,,,H99,ali2 (CNAG_02341),chromosome 6,,,,,PHI:9848; PHI:9850; PHI:9851,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,cyclin binding protein,,,,reduced virulence,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15399,PHI:9850,UniProt,J9VQX7,GenBank,AFR96867,,,H99,ali3 (CNAG_04137),chromosome 9,,,,,PHI:9848; PHI:9849; PHI:9851,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,arrestin_C domain-containing protein,,,,reduced virulence,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15400,PHI:9851,UniProt,J9VWA9,GenBank,AFR98767,,,H99,ali4 (CNAG_05343),chromosome 14,,,,,PHI:9848; PHI:9849; PHI:9850,5207,Cryptococcus neoformans,,MATa KN99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,arrestin_C domain-containing protein,,,,reduced virulence,,,,,,,,,,no,caffeine; SDS; NaCl; sorbitol; glycerol,caffeine: CHEBI:27732; SDS: CHEBI:8984; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; glycerol: CHEBI:17754,,,,,gene mutation; gene complementation,,,YVS,31744923,PubMed,10.1128/mBio.02682-19,mBio. 2019 Nov 19;10(6),andrew.alspaugh@duke.edu,Ali1 had modest contributions to in vitro survival in the presence of macrophages but did not promote in vivo virulence in a murine inhalation infection model.,C L Telzrow 2019,2019,4 genes,Telzrow-2019-A Fungal Arrestin Protein Contrib,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15401,PHI:9852,UniProt,W8U4L6,GenBank,AUS74103,,,MRSA107,eap,,,,,,,1280,Staphylococcus aureus,,MR23,skin infection; food poisoning; respiratory disease,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,adherence protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30670553,PubMed,10.1128/IAI.00894-18,Infect Immun. 2019 Mar 25;87(4),ssugimoto@jikei.ac.jp,The rate of mortality of larvae infected with the Δeap ΔsasG strain was significantly lower than that of wild type which was associated with the strain's reduced biofilm-forming capacity in vitro.,K Yonemoto 2019,2019,2 genes,Yonemoto-2019-Redundant and Distinct Roles of,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15402,PHI:9853,UniProt,A0A2Z6G142,GenBank,BBE38030,,,MR23,sasG,,,,,,,1280,Staphylococcus aureus,,MR23,skin infection; food poisoning; respiratory disease,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,surface protein G,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30670553,PubMed,10.1128/IAI.00894-18,Infect Immun. 2019 Mar 25;87(4),ssugimoto@jikei.ac.jp,The rate of mortality of larvae infected with the Δeap ΔsasG strain was significantly lower than that of wild type which was associated with the strain's reduced biofilm-forming capacity in vitro.,K Yonemoto 2019,2019,2 genes,Yonemoto-2019-Redundant and Distinct Roles of,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15403,PHI:9853,UniProt,A0A2Z6G142,GenBank,BBE38030,,,MR23,sasG,,,,,,PHI:9852,1280,Staphylococcus aureus,,MR23,skin infection; food poisoning; respiratory disease,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,adherence protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30670553,PubMed,10.1128/IAI.00894-18,Infect Immun. 2019 Mar 25;87(4),ssugimoto@jikei.ac.jp,The rate of mortality of larvae infected with the Δeap ΔsasG strain was significantly lower than that of wild type which was associated with the strain's reduced biofilm-forming capacity in vitro.,K Yonemoto 2019,2019,2 genes,Yonemoto-2019-Redundant and Distinct Roles of,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15404,PHI:9852,UniProt,W8U4L6,GenBank,AUS74103,,,MRSA107,eap,,,,,,PHI:9853,1280,Staphylococcus aureus,,MR23,skin infection; food poisoning; respiratory disease,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,surface protein G,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30670553,PubMed,10.1128/IAI.00894-18,Infect Immun. 2019 Mar 25;87(4),ssugimoto@jikei.ac.jp,The rate of mortality of larvae infected with the Δeap ΔsasG strain was significantly lower than that of wild type which was associated with the strain's reduced biofilm-forming capacity in vitro.,K Yonemoto 2019,2019,2 genes,Yonemoto-2019-Redundant and Distinct Roles of,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15405,PHI:9854,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,pGP3,,,,,,,83560,Chlamydia muridarum,1434769,Nigg3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,stomach; duodenum; jejunum; ileum; cecum; colon; rectum; vagina; uterus; ovary,genital tract virulence factor,,,,reduced virulence,,,,,,,,,,no,HCl; pepsin; sarkosyl,HCl: CHEBI:17883; pepsin CAS no.: CAS:9001-75-6; sarkosyl CAS no.: CAS:137-16-6,,,,,gene mutation,,,YVS,30858342,PubMed,10.1128/IAI.00844-18,Infect Immun. 2019 Apr 23;87(5),Zhongg@uthscsa.edu,"The pGP3-deficient mutant was rapidly cleared in the stomach and was 100-fold more susceptible to gastric killing, and in the genital tract, survival was reduced in the mouse vagina and susceptibility to vaginal killing increased by 8 times.",T Zhang 2019,2019,1 gene,Zhang-2019-The plasmid-encoded pGP3 promotes C,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15406,PHI:9855,,no data found,,,,,,cps,,,,,,,573,Klebsiella pneumoniae,,Kp52.145,pneumonia,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,lung,capsule polysaccharide,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31796543,PubMed,10.1128/mBio.02802-19,mBio. 2019 Dec 3;10(6),j.bengoechea@qub.ac.uk,Infection with the cps mutant strain reduced alveolar septal thickening.,A Dumigan 2019,2019,1 gene,Dumigan-2019-A Porcine Ex Vivo Lung Perfusion,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15407,PHI:9856,UniProt,A3M8A5,GenBank,ABO13149,,,ATCC 17978,A1S_2736 (RND),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,RND family drug transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15408,PHI:9857,UniProt,A3MA16,GenBank,ABO13760,,,ATCC 17978,A1S_3371 (MATE),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative MATE family drug transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15409,PHI:9858,UniProt,A3M2L0,GenBank,ABO11154,,,ATCC 17978,A1S_0710 (SMR),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative SMR family drug transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15410,PHI:9859,UniProt,A3M426,GenBank,ABO11670,,,ATCC 17978,A1S_1242,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative ABC family drug transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15411,PHI:9860,UniProt,A3M7Z5,GenBank,ABO13039,,,ATCC 17978,A1S_2622,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15412,PHI:9861,UniProt,A3M245,GenBank,ABO10989,,,ATCC 17978,A1S_0536,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,macrolide transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15413,PHI:9862,UniProt,A3M4W8,GenBank,ABO11962,,,ATCC 17978,A1S_1535,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15414,PHI:9863,UniProt,A3M0S8,GenBank,ABO10522,,,ATCC 17978,A1S_0027,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,alkanesulfonate transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15415,PHI:9864,UniProt,A3M3J5,GenBank,ABO11489,,,ATCC 17978,A1S_1057 (ABC),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative oligopeptide transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15416,PHI:9865,UniProt,A3M4T6,GenBank,ABO11930,,,ATCC 17978,A1S_1503,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,transmembrane pair,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15417,PHI:9866,UniProt,A3M6E6,GenBank,ABO12490,,,ATCC 17978,A1S_2063 (PACE),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,putative membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15418,PHI:9856,UniProt,A3M8A5,GenBank,ABO13149,,,ATCC 17978,A1S_2736 (RND),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,RND family drug transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15419,PHI:9857,UniProt,A3MA16,GenBank,ABO13760,,,ATCC 17978,A1S_3371 (MATE),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative MATE family drug transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15420,PHI:9858,UniProt,A3M2L0,GenBank,ABO11154,,,ATCC 17978,A1S_0710 (SMR),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative SMR family drug transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15421,PHI:9859,UniProt,A3M426,GenBank,ABO11670,,,ATCC 17978,A1S_1242,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative ABC family drug transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15422,PHI:9860,UniProt,A3M7Z5,GenBank,ABO13039,,,ATCC 17978,A1S_2622,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15423,PHI:9861,UniProt,A3M245,GenBank,ABO10989,,,ATCC 17978,A1S_0536,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,macrolide transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15424,PHI:9862,UniProt,A3M4W8,GenBank,ABO11962,,,ATCC 17978,A1S_1535,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15425,PHI:9863,UniProt,A3M0S8,GenBank,ABO10522,,,ATCC 17978,A1S_0027,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,alkanesulfonate transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15426,PHI:9864,UniProt,A3M3J5,GenBank,ABO11489,,,ATCC 17978,A1S_1057 (ABC),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative oligopeptide transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15427,PHI:9865,UniProt,A3M4T6,GenBank,ABO11930,,,ATCC 17978,A1S_1503,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,transmembrane pair,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15428,PHI:9866,UniProt,A3M6E6,GenBank,ABO12490,,,ATCC 17978,A1S_2063 (PACE),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30642939,PubMed,10.1128/AAC.02190-18,Antimicrob Agents Chemother. 2019 Feb 26;63(3),aranda@uab.cat,All mutants lacking an efflux transporter involved in surface-associated motility were less virulent.,M Perez-Varela 2019,2019,11 genes,Perez-Varela-2019-The roles of efflux pumps fr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15429,PHI:9867,UniProt,A0A0D1E191,GenBank,KIS69929,,,521,Pdi (UMAG_10156),chromosome 5,,,,,,5270,Ustilago maydis,559306,FB1,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,protein disulfide-isomerase,,,,reduced virulence,,no,no,,,,,,,no,calcofluor white; Congo red; tunicamycin; sorbitol; DMSO; H2O2; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; tunicamycin: CHEBI:29699; sorbitol: CHEBI:17924; DMSO: CHEBI:28262; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,31730668,PubMed,10.1371/journal.ppat.1007687,PLoS Pathog. 2019 Nov 15;15(11),aferalv@upo.es,Loss of Pdi1 N-glycosylation mimiced Δpdi1 virulence defects .,M Marin-Menguian 2019,2019,1 gene,Marin-Menguiano-2019-N-glycosylation of the pr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15430,PHI:9867,UniProt,A0A0D1E191,GenBank,KIS69929,,,521,Pdi (UMAG_10156),chromosome 5,"putative O-glycosylation sites were substituted with alanine (S4A, S24A, S340A, S344A, S346A, S350A, S477A and T486A) residues (Pdi1ΔO-gly)",,,,,5270,Ustilago maydis,559306,FB1,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,protein disulfide-isomerase,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white; Congo red; tunicamycin; sorbitol; DMSO; H2O2; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; tunicamycin: CHEBI:29699; sorbitol: CHEBI:17924; DMSO: CHEBI:28262; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene mutation; gene complementation,,,YVS,31730668,PubMed,10.1371/journal.ppat.1007687,PLoS Pathog. 2019 Nov 15;15(11),aferalv@upo.es,Loss of Pdi1 N-glycosylation mimiced Δpdi1 virulence defects .,M Marin-Menguian 2019,2019,1 gene,Marin-Menguiano-2019-N-glycosylation of the pr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15431,PHI:9867,UniProt,A0A0D1E191,GenBank,KIS69929,,,521,Pdi (UMAG_10156),chromosome 5,putative N-glycosylation sites were substituted with glutamine (N36Q and N484Q) residues (Pdi1ΔN-gly),,,,,5270,Ustilago maydis,559306,FB1,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,protein disulfide-isomerase,,,,reduced virulence,,,,,,,,,,no,calcofluor white; Congo red; tunicamycin; sorbitol; DMSO; H2O2; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; tunicamycin: CHEBI:29699; sorbitol: CHEBI:17924; DMSO: CHEBI:28262; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene mutation; gene complementation,,,YVS,31730668,PubMed,10.1371/journal.ppat.1007687,PLoS Pathog. 2019 Nov 15;15(11),aferalv@upo.es,Loss of Pdi1 N-glycosylation mimiced Δpdi1 virulence defects .,M Marin-Menguian 2019,2019,1 gene,Marin-Menguiano-2019-N-glycosylation of the pr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15432,PHI:9867,UniProt,A0A0D1E191,GenBank,KIS69929,,,521,Pdi (UMAG_10156),chromosome 5,"putative O- and N-glycosylation sites were substituted with alanine (S4A, S24A, S340A, S344A, S346A, S350A, S477A and T486A) and glutamine (N36Q and N484Q) residues (Pdi1ΔN,O-gly)",,,,,5270,Ustilago maydis,559306,FB1,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,seedling,protein disulfide-isomerase,,,,reduced virulence,,,,,,,,,,no,calcofluor white; Congo red; tunicamycin; sorbitol; DMSO; H2O2; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; tunicamycin: CHEBI:29699; sorbitol: CHEBI:17924; DMSO: CHEBI:28262; H2O2: CHEBI:16240; NaCl: CHEBI:267101,,,,,gene mutation; gene complementation,,,YVS,31730668,PubMed,10.1371/journal.ppat.1007687,PLoS Pathog. 2019 Nov 15;15(11),aferalv@upo.es,Loss of Pdi1 N-glycosylation mimiced Δpdi1 virulence defects .,M Marin-Menguian 2019,2019,1 gene,Marin-Menguiano-2019-N-glycosylation of the pr,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15433,PHI:9868,UniProt,Q4QNL8,GenBank,AAX87379,,,86-028NP,vapB-1,,,,,,PHI:9869,727,Haemophilus influenzae,,86-028NP,otitis media; invasive disease,primates,9606,Homo sapiens (related: human),,,,bronchial epithelial cell line,antitoxin,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full; gene complementation,,,YVS,30936373,PubMed,10.1128/JB.00026-19,J Bacteriol. 2019 May 22;201(12),ddaines@odu.edu,Targeting any of these individual residues in the toxin could potentially result in a significant decrease in survival of NTHi during infection.EpiAirway tissues,A L Molinaro 2019,2019,2 genes,Molinaro-2019-Crystal structure of VapBC-1 fro,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15434,PHI:9869,UniProt,Q4QNL7,GenBank,AAX87380,,,86-028NP,vapC-1,,,,,,PHI:9868,727,Haemophilus influenzae,,86-028NP,otitis media; invasive disease,primates,9606,Homo sapiens (related: human),,,,bronchial epithelial cell line,ribonuclease,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full; gene complementation,,,YVS,30936373,PubMed,10.1128/JB.00026-19,J Bacteriol. 2019 May 22;201(12),ddaines@odu.edu,Targeting any of these individual residues in the toxin could potentially result in a significant decrease in survival of NTHi during infection.EpiAirway tissues,A L Molinaro 2019,2019,2 genes,Molinaro-2019-Crystal structure of VapBC-1 fro,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15435,PHI:9869,UniProt,Q4QNL7,GenBank,AAX87380,,,86-028NP,vapC-1,,D6N; D99N; D6N and D99N; E43Q; E43Q and D99N; E120Q,,,,,727,Haemophilus influenzae,,86-028NP,otitis media; invasive disease,primates,9606,Homo sapiens (related: human),,,,bronchial epithelial cell line,ribonuclease,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene mutation; gene complementation,,,YVS,30936373,PubMed,10.1128/JB.00026-19,J Bacteriol. 2019 May 22;201(12),ddaines@odu.edu,Targeting any of these individual residues in the toxin could potentially result in a significant decrease in survival of NTHi during infection.EpiAirway tissues,A L Molinaro 2019,2019,2 genes,Molinaro-2019-Crystal structure of VapBC-1 fro,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15436,PHI:9870,UniProt,Q5ZYD1,GenBank,AAU26538,,,Philadelphia 1,icmT,,,,,,,446,Legionella pneumophila,,JR32,Legionnaires' disease,primates,9606,Homo sapiens (related: human),,,,macrophage,uncharacterized protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28867389,PubMed,10.1016/j.chom.2017.07.020,Cell Host Microbe. 2017 Sep 13;22(3):302-316,cbuch@pasteur.fr,Host gene alteration data available for DNM1L. The T4SS effector MitF induced DNM1L-dependent mitochondrial fragmentation.Monocyte-derived macrophages,P Escoll 2017,2017,4 genes,Escoll-2017-Legionella pneumophila Modulates M,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15437,PHI:9871,UniProt,Q5WTB2,GenBank,CAH16854,,,Lens,dotA,,,,,,,446,Legionella pneumophila,297246,Paris,Legionnaires' disease,primates,9606,Homo sapiens (related: human),,,,macrophage,defect in organelle trafficking protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28867389,PubMed,10.1016/j.chom.2017.07.020,Cell Host Microbe. 2017 Sep 13;22(3):302-316,cbuch@pasteur.fr,Host gene alteration data available for DNM1L. The T4SS effector MitF induced DNM1L-dependent mitochondrial fragmentation.Monocyte-derived macrophages,P Escoll 2017,2017,4 genes,Escoll-2017-Legionella pneumophila Modulates M,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15438,PHI:9872,UniProt,Q5ZU32,GenBank,AAU28045,,,Philadelphia 1,MitF/ LegG1 (Lpg1976),,,,,,,446,Legionella pneumophila,297246,Paris,Legionnaires' disease,primates,9606,Homo sapiens (related: human),,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28867389,PubMed,10.1016/j.chom.2017.07.020,Cell Host Microbe. 2017 Sep 13;22(3):302-316,cbuch@pasteur.fr,Host gene alteration data available for DNM1L. The T4SS effector MitF induced DNM1L-dependent mitochondrial fragmentation.Monocyte-derived macrophages,P Escoll 2017,2017,4 genes,Escoll-2017-Legionella pneumophila Modulates M,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15439,PHI:9873,UniProt,Q5WV98,GenBank,CAH16159,,,Lens,RalF,,,,,,,446,Legionella pneumophila,297246,Paris,Legionnaires' disease,primates,9606,Homo sapiens (related: human),,,,macrophage,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28867389,PubMed,10.1016/j.chom.2017.07.020,Cell Host Microbe. 2017 Sep 13;22(3):302-316,cbuch@pasteur.fr,Host gene alteration data available for DNM1L. The T4SS effector MitF induced DNM1L-dependent mitochondrial fragmentation.Monocyte-derived macrophages,P Escoll 2017,2017,4 genes,Escoll-2017-Legionella pneumophila Modulates M,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15440,PHI:9874,UniProt,Q9P8P2,GenBank,AF223383_1,,,H99,plb1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,phospholipase B,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin,ciprofloxacin: CHEBI:100241,,,,,gene mutation; gene complementation,,,YVS,29858266,PubMed,10.4049/jimmunol.1700958,J Immunol. 2018 Jul 15;201(2):583-603,acasade1@jhu.edu,Macrophages infected with a C. neoformans Δplb1 mutant had reduced phagolysosomal membrane permeabilization (PMP) compared with wild type strain.,C M De Leon-Rodriguez 2018,2018,1 gene,De Leon-Rodrigu-2018-The Outcome of the Crypto,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15441,PHI:9874,UniProt,Q9P8P2,GenBank,AF223383_1,,,H99,plb1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774.16 cell line,,,macrophage,phospholipase B,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin,ciprofloxacin: CHEBI:100241,,,,,gene mutation; gene complementation,,,YVS,29858266,PubMed,10.4049/jimmunol.1700958,J Immunol. 2018 Jul 15;201(2):583-603,acasade1@jhu.edu,Macrophages infected with a C. neoformans Δplb1 mutant had reduced phagolysosomal membrane permeabilization (PMP) compared with wild type strain.,C M De Leon-Rodriguez 2018,2018,1 gene,De Leon-Rodrigu-2018-The Outcome of the Crypto,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15442,PHI:9875,UniProt,Q2FI75,GenBank,ABD21733,,,USA300_FPR3757,yjbI (SAUSA300_0904),,,,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; liver; spleen,conserved hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,"diethylenetriamine NONOate; H2O2; methyl viologen; 2,2-dipyridyl","diethylenetriamine NONOate: CHEBI:50154; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786; 2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,30885928,PubMed,10.1128/IAI.00155-19,Infect Immun. 2019 May 21;87(6),jbose@kumc.edu,Absence of YjbIH resulted in enhanced colonization of animals during a systemic infection.,C M Austin 2019,2019,2 genes,Austin-2019-Contribution of YjbIH to virulence,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15443,PHI:9876,UniProt,A0A0H2XHR2,GenBank,ABD22445,,,USA300_FPR3757,yjbH (SAUSA300_0903),,,,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; liver; spleen,protozoan/cyanobacterial globin family protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,"diethylenetriamine NONOate; H2O2; methyl viologen; 2,2-dipyridyl","diethylenetriamine NONOate: CHEBI:50154; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786; 2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,30885928,PubMed,10.1128/IAI.00155-19,Infect Immun. 2019 May 21;87(6),jbose@kumc.edu,Absence of YjbIH resulted in enhanced colonization of animals during a systemic infection.,C M Austin 2019,2019,2 genes,Austin-2019-Contribution of YjbIH to virulence,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15444,PHI:9875,UniProt,Q2FI75,GenBank,ABD21733,,,USA300_FPR3757,yjbI (SAUSA300_0904),,,,,,PHI:9876,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; liver; spleen,conserved hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,"diethylenetriamine NONOate; H2O2; methyl viologen; 2,2-dipyridyl","diethylenetriamine NONOate: CHEBI:50154; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786; 2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,30885928,PubMed,10.1128/IAI.00155-19,Infect Immun. 2019 May 21;87(6),jbose@kumc.edu,Absence of YjbIH resulted in enhanced colonization of animals during a systemic infection.,C M Austin 2019,2019,2 genes,Austin-2019-Contribution of YjbIH to virulence,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15445,PHI:9876,UniProt,A0A0H2XHR2,GenBank,ABD22445,,,USA300_FPR3757,yjbH (SAUSA300_0903),,,,,,PHI:9875,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; liver; spleen,protozoan/cyanobacterial globin family protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,"diethylenetriamine NONOate; H2O2; methyl viologen; 2,2-dipyridyl","diethylenetriamine NONOate: CHEBI:50154; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786; 2,2-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,30885928,PubMed,10.1128/IAI.00155-19,Infect Immun. 2019 May 21;87(6),jbose@kumc.edu,Absence of YjbIH resulted in enhanced colonization of animals during a systemic infection.,C M Austin 2019,2019,2 genes,Austin-2019-Contribution of YjbIH to virulence,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15446,PHI:9877,UniProt,A0A0H2XEK8,GenBank,ABD20720,,,USA300_FPR3757,SAUSA300_1984 (mroQ),,,,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,macrophage,membrane protease regulator of Agr quorum sensing,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30833334,PubMed,10.1128/IAI.00019-19,Infect Immun. 2019 Apr 23;87(5),falonzo@luc.edu,"The ΔmroQ and Δagr mutants exhibited significantly reduced hemolytic activity compared to the WT, and both strains were similarly attenuated in a murine intradermal infection model.",C J Cosgriff 2019,2019,5 genes,Cosgriff-2019-Control of Staphylococcus aureus,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15447,PHI:9877,UniProt,A0A0H2XEK8,GenBank,ABD20720,,,USA300_FPR3757,SAUSA300_1984 (mroQ),,ΔmroQ(E141A),,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,macrophage,membrane protease regulator of Agr quorum sensing,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30833334,PubMed,10.1128/IAI.00019-19,Infect Immun. 2019 Apr 23;87(5),falonzo@luc.edu,"The ΔmroQ and Δagr mutants exhibited significantly reduced hemolytic activity compared to the WT, and both strains were similarly attenuated in a murine intradermal infection model.",C J Cosgriff 2019,2019,5 genes,Cosgriff-2019-Control of Staphylococcus aureus,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15448,PHI:9877,UniProt,A0A0H2XEK8,GenBank,ABD20720,,,USA300_FPR3757,SAUSA300_1984 (mroQ),,ΔmroQ(E142A); ΔmroQ(H180A),,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,macrophage,membrane protease regulator of Agr quorum sensing,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30833334,PubMed,10.1128/IAI.00019-19,Infect Immun. 2019 Apr 23;87(5),falonzo@luc.edu,"The ΔmroQ and Δagr mutants exhibited significantly reduced hemolytic activity compared to the WT, and both strains were similarly attenuated in a murine intradermal infection model.",C J Cosgriff 2019,2019,5 genes,Cosgriff-2019-Control of Staphylococcus aureus,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15449,PHI:9878,UniProt,Q2FWM7,GenBank,AF230358_2,,,RN4220,agrB,,,,,,PHI:9879; PHI:9880; PHI:9881,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,macrophage,accessory gene regulator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30833334,PubMed,10.1128/IAI.00019-19,Infect Immun. 2019 Apr 23;87(5),falonzo@luc.edu,"The ΔmroQ and Δagr mutants exhibited significantly reduced hemolytic activity compared to the WT, and both strains were similarly attenuated in a murine intradermal infection model.",C J Cosgriff 2019,2019,5 genes,Cosgriff-2019-Control of Staphylococcus aureus,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15450,PHI:9879,UniProt,Q53643,GenBank,AAB80779,,,KSI54 (S6C),agrD,,,,,,PHI:9878; PHI:9880; PHI:9881,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,macrophage,accessory gene regulator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30833334,PubMed,10.1128/IAI.00019-19,Infect Immun. 2019 Apr 23;87(5),falonzo@luc.edu,"The ΔmroQ and Δagr mutants exhibited significantly reduced hemolytic activity compared to the WT, and both strains were similarly attenuated in a murine intradermal infection model.",C J Cosgriff 2019,2019,5 genes,Cosgriff-2019-Control of Staphylococcus aureus,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15451,PHI:9880,UniProt,O07911,GenBank,AAB80777,,,KSI54 (S6C),agrC,,,,,,PHI:9878; PHI:9879; PHI:9881,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,macrophage,accessory gene regulator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30833334,PubMed,10.1128/IAI.00019-19,Infect Immun. 2019 Apr 23;87(5),falonzo@luc.edu,"The ΔmroQ and Δagr mutants exhibited significantly reduced hemolytic activity compared to the WT, and both strains were similarly attenuated in a murine intradermal infection model.",C J Cosgriff 2019,2019,5 genes,Cosgriff-2019-Control of Staphylococcus aureus,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15452,PHI:9881,UniProt,P0A0I5,GenBank,BAB43126,,,N315,agrA,,,,,,PHI:9878; PHI:9879; PHI:9880,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,macrophage,accessory gene regulator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30833334,PubMed,10.1128/IAI.00019-19,Infect Immun. 2019 Apr 23;87(5),falonzo@luc.edu,"The ΔmroQ and Δagr mutants exhibited significantly reduced hemolytic activity compared to the WT, and both strains were similarly attenuated in a murine intradermal infection model.",C J Cosgriff 2019,2019,5 genes,Cosgriff-2019-Control of Staphylococcus aureus,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15453,PHI:9882,UniProt,A6QIR4,GenBank,BAF68246,,,Newman,mazF,,,,,,,1280,Staphylococcus aureus,,JE2,abscess; sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,thigh muscle,endoribonuclease,,,,increased virulence (hypervirulence),,,,,,,,,,no,cefazolin; vancomycin,cefazolin: CHEBI:474053; vancomycin: CHEBI:28001,,,,,gene mutation; gene complementation,,,YVS,31772059,PubMed,10.1128/mBio.01658-19,mBio. 2019 Nov 26;10(6). pii: e01658-19,urishk2@upmc.edu,MazF contributed to a phenotype of decreased virulence and pathogenesis.,D Ma 2019,2019,5 genes,Ma-2019-The Toxin-Antitoxin MazEF Drives Staph,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15454,PHI:9883,UniProt,Q9RQP9,GenBank,AF086783_3,,,ATCC 35556,icaA,,mazF::Tn/ΔicaADBC,,,,PHI:9884; PHI:9885; PHI:9886; PHI:9882,1280,Staphylococcus aureus,,JE2,abscess; sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,thigh muscle,"poly-beta-1,6-N-acetyl-D-glucosamine synthase",,,,unaffected pathogenicity,,,,,,,,,,no,cefazolin; vancomycin,cefazolin: CHEBI:474053; vancomycin: CHEBI:28001,,,,,gene deletion: full,,,YVS,31772059,PubMed,10.1128/mBio.01658-19,mBio. 2019 Nov 26;10(6). pii: e01658-19,urishk2@upmc.edu,The ability of the mazF::Tn/ΔicaADBC strain to restore survival in the murine abscess model confirmed a role for ica in the control of biofilm formation in pathogenesis.,D Ma 2019,2019,5 genes,Ma-2019-The Toxin-Antitoxin MazEF Drives Staph,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15455,PHI:9884,UniProt,Q9RQP7,GenBank,AF086783_5,,,ATCC 35556,icaB,,mazF::Tn/ΔicaADBC,,,,PHI:9883; PHI:9885; PHI:9886; PHI:9882,1280,Staphylococcus aureus,,JE2,abscess; sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,thigh muscle,"poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase",,,,unaffected pathogenicity,,,,,,,,,,no,cefazolin; vancomycin,cefazolin: CHEBI:474053; vancomycin: CHEBI:28001,,,,,gene deletion: full,,,YVS,31772059,PubMed,10.1128/mBio.01658-19,mBio. 2019 Nov 26;10(6). pii: e01658-19,urishk2@upmc.edu,The ability of the mazF::Tn/ΔicaADBC strain to restore survival in the murine abscess model confirmed a role for ica in the control of biofilm formation in pathogenesis.,D Ma 2019,2019,5 genes,Ma-2019-The Toxin-Antitoxin MazEF Drives Staph,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15456,PHI:9885,UniProt,Q9RQP6,GenBank,AF086783_6,,,ATCC 35556,icaC,,mazF::Tn/ΔicaADBC,,,,PHI:9883; PHI:9884; PHI:9886; PHI:9882,1280,Staphylococcus aureus,,JE2,abscess; sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,thigh muscle,"probable poly-beta-1,6-N-acetyl-D-glucosamine export protein",,,,unaffected pathogenicity,,,,,,,,,,no,cefazolin; vancomycin,cefazolin: CHEBI:474053; vancomycin: CHEBI:28001,,,,,gene deletion: full,,,YVS,31772059,PubMed,10.1128/mBio.01658-19,mBio. 2019 Nov 26;10(6). pii: e01658-19,urishk2@upmc.edu,The ability of the mazF::Tn/ΔicaADBC strain to restore survival in the murine abscess model confirmed a role for ica in the control of biofilm formation in pathogenesis.,D Ma 2019,2019,5 genes,Ma-2019-The Toxin-Antitoxin MazEF Drives Staph,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15457,PHI:9886,UniProt,Q9RQP8,GenBank,AF086783_4,,,ATCC 35556,icaD,,mazF::Tn/ΔicaADBC,,,,PHI:9883; PHI:9884; PHI:9885; PHI:9882,1280,Staphylococcus aureus,,JE2,abscess; sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,thigh muscle,"poly-beta-1,6-N-acetyl-D-glucosamine synthesis protein",,,,unaffected pathogenicity,,,,,,,,,,no,cefazolin; vancomycin,cefazolin: CHEBI:474053; vancomycin: CHEBI:28001,,,,,gene deletion: full,,,YVS,31772059,PubMed,10.1128/mBio.01658-19,mBio. 2019 Nov 26;10(6). pii: e01658-19,urishk2@upmc.edu,The ability of the mazF::Tn/ΔicaADBC strain to restore survival in the murine abscess model confirmed a role for ica in the control of biofilm formation in pathogenesis.,D Ma 2019,2019,5 genes,Ma-2019-The Toxin-Antitoxin MazEF Drives Staph,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15458,PHI:9882,UniProt,A6QIR4,GenBank,BAF68246,,,Newman,mazF,,mazF::Tn/ΔicaADBC,,,,PHI:9883; PHI:9884; PHI:9885; PHI:9886,1280,Staphylococcus aureus,,JE2,abscess; sepsis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,thigh muscle,endoribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,cefazolin; vancomycin,cefazolin: CHEBI:474053; vancomycin: CHEBI:28001,,,,,gene mutation; gene complementation,,,YVS,31772059,PubMed,10.1128/mBio.01658-19,mBio. 2019 Nov 26;10(6). pii: e01658-19,urishk2@upmc.edu,The ability of the mazF::Tn/ΔicaADBC strain to restore survival in the murine abscess model confirmed a role for ica in the control of biofilm formation in pathogenesis.,D Ma 2019,2019,5 genes,Ma-2019-The Toxin-Antitoxin MazEF Drives Staph,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15459,PHI:9887,UniProt,A0A0H3AIG7,GenBank,ABQ19866,,,O395,VgrG-1,chromosome 1,VgrG-1-ACD V1013A and M1014A; I1017A and K1018A,,,,,666,Vibrio cholerae,45888,serogroup O139,cholera,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,actin cross-linking toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31002899,PubMed,10.1016/j.ijbiomac.2019.04.026,Int J Biol Macromol. 2019 Jul 15;133:775-785,spm@iiserkol.ac.in,VgrG-1-ACD having the mutated ABM could not cross-link actin efficiently in vitro and manifested less actin cytoskeleton disruption when transfected in HeLa cells.,P Dutta 2019,2019,1 gene,Dutta-2019-Presence of actin binding motif in,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15460,PHI:9888,UniProt,Q0SXL9,GenBank,ABF06196,,,8401,fimA,,,,,,,562,Escherichia coli,,JM103,infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,major type 1 subunit fimbrin (pilin),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,"Although fimbria deficiency in Shigella conferred its poor ability to adhere intrinsically, this deficiency greatly augmented the ability of HD5 to mediate adhesion to host epithelial cells.",D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15461,PHI:9889,UniProt,P0A1K9,GenBank,AAA26543,,,M9OT,Spa33,,,,,,,623,Shigella flexneri,,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,surface presentation of antigens protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,Deletion of multiple bacterial surface proteins led to reduced HD5-mediated adhesion.,D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15462,PHI:9890,UniProt,Q7BCK4,GenBank,CAC05837,,,M90T,IcsA,,,,,,,623,Shigella flexneri,,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,outer membrane protein IcsA autotransporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,Deletion of multiple bacterial surface proteins led to reduced HD5-mediated adhesion.,D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15463,PHI:9891,UniProt,A0A2S4N3N0,GenBank,AAN42586,,,301,OmpA,,,,,,,623,Shigella flexneri,,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,Deletion of multiple bacterial surface proteins led to reduced HD5-mediated adhesion.,D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15464,PHI:9892,UniProt,A0A2S4MYF8,GenBank,AAN43817,,,301,OmpC,,,,,,,623,Shigella flexneri,,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,outer membrane protein C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,Deletion of multiple bacterial surface proteins led to reduced HD5-mediated adhesion.,D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15465,PHI:9891,UniProt,A0A2S4N3N0,GenBank,AAN42586,,,301,OmpA,,,,,,PHI:9892,623,Shigella flexneri,,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,Deletion of multiple bacterial surface proteins led to reduced HD5-mediated adhesion.,D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15466,PHI:9892,UniProt,A0A2S4MYF8,GenBank,AAN43817,,,301,OmpC,,,,,,PHI:9891,623,Shigella flexneri,,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,outer membrane protein C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,Deletion of multiple bacterial surface proteins led to reduced HD5-mediated adhesion.,D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15467,PHI:9889,UniProt,P0A1K9,GenBank,AAA26543,,,M9OT,Spa33,,,,,,PHI:9891,623,Shigella flexneri,,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,surface presentation of antigens protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,Deletion of multiple bacterial surface proteins led to reduced HD5-mediated adhesion.,D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15468,PHI:9891,UniProt,A0A2S4N3N0,GenBank,AAN42586,,,301,OmpA,,,,,,PHI:9889,623,Shigella flexneri,,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,Deletion of multiple bacterial surface proteins led to reduced HD5-mediated adhesion.,D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15469,PHI:9889,UniProt,P0A1K9,GenBank,AAA26543,,,M9OT,Spa33,,,,,,PHI:9892,623,Shigella flexneri,,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,surface presentation of antigens protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,Deletion of multiple bacterial surface proteins led to reduced HD5-mediated adhesion.,D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15470,PHI:9892,UniProt,A0A2S4MYF8,GenBank,AAN43817,,,301,OmpC,,,,,,PHI:9889,623,Shigella flexneri,,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,outer membrane protein C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,YVS,29858013,PubMed,10.1016/j.immuni.2018.04.014,Immunity. 2018 Jun 19;48(6):1233-1244.e6,yongping.shao@xjtu.edu.cn,Deletion of multiple bacterial surface proteins led to reduced HD5-mediated adhesion.,D Xu 2018,2018,5 genes,Xu-2018-Human Enteric alpha-Defensin 5 Promote,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15471,PHI:9893,UniProt,Q6VE93,GenBank,RVU53737,,,WSPS007,HopZ1a,,,,,,,317,Pseudomonas syringae,,pv. syringae strain A2,bacterial speck (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31012804,PubMed,10.1094/MPMI-04-19-0105-R,Mol Plant Microbe Interact. 2019 Sep;32(9):1229-1242,boernke@igzev.de,Downregulation of NbREM4 did not affect HopZ1a-dependent ETI.,P Albers 2019,2019,2 genes,Albers-2019-A remorin from Nicotiana benthamia,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15472,PHI:9893,UniProt,Q6VE93,GenBank,RVU53737,,,WSPS007,HopZ1a,,HopZ1 C/A carrying a cysteine to alanine substitution,,,,,317,Pseudomonas syringae,,pv. syringae strain A2,bacterial speck (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31012804,PubMed,10.1094/MPMI-04-19-0105-R,Mol Plant Microbe Interact. 2019 Sep;32(9):1229-1242,boernke@igzev.de,Ion leakage from HopZ1a-infiltrated leaf tissue was significantly increased whereas expression of inactive HopZ1C/A variant did not increase electrolyte efflux.,P Albers 2019,2019,2 genes,Albers-2019-A remorin from Nicotiana benthamia,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15473,PHI:9894,UniProt,Q3BYG1,GenBank,CAJ22102,,,85-10,AvrRxv,,,,,,,339,Xanthomonas campestris,,pv. campestris,bacterial speck (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31012804,PubMed,10.1094/MPMI-04-19-0105-R,Mol Plant Microbe Interact. 2019 Sep;32(9):1229-1242,boernke@igzev.de,HopZ1a infiltrated areas showed clear signs of cell death that were even more prominent than those triggered by AvrRxv.,P Albers 2019,2019,2 genes,Albers-2019-A remorin from Nicotiana benthamia,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15474,PHI:9895,UniProt,G9MUG3,GenBank,XP_013956100,,,Gv29-8,TBRG-1,,,,,,,29875,Trichoderma virens,413071,Gv29-8,non-pathogenic: biocontrol,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,seed; seedling,trichoderma big Ras-GTPase-1,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31730908,PubMed,10.1016/j.fgb.2019.103292,Fungal Genet Biol. 2019 Nov 12;136:103292,scasas@ipicyt.edu.mx,Seedlings treated with Δtbrg-1 showed shorter and weaker roots compared with those treated with the wt. ΔTbrg-1 strain also showed a diminished biocontrol capability against R. solani.,M Dautt-Castro 2019,2019,1 gene,Dautt-Castro-2019-TBRG-1 a Ras-like protein in,BATCH_098C,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15475,PHI:9896,UniProt,P23865,GenBank,BAA00577,,,K-12,Prc,,,,,,,562,Escherichia coli,439184,RS218,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney,tail-specific protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31900139,PubMed,10.1186/s12929-019-0605-y,J Biomed Sci. 2020 Jan 3;27(1):14,chteng@mail.ncku.edu.tw,The impaired motility of the prc mutant was responsible for attenuated UT colonization of the mutant.,W C Huang 2020,2020,2 genes,Huang-2020-The role of the bacterial protease,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15476,PHI:9897,UniProt,P00722,GenBank,AAA24053,,,,lacZ,,,,,,,562,Escherichia coli,439184,RS218,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney,beta-galactosidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31900139,PubMed,10.1186/s12929-019-0605-y,J Biomed Sci. 2020 Jan 3;27(1):14,chteng@mail.ncku.edu.tw,The impaired motility of the prc mutant was responsible for attenuated UT colonization of the mutant.,W C Huang 2020,2020,2 genes,Huang-2020-The role of the bacterial protease,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15477,PHI:9898,UniProt,A3M3H0,GenBank,ABO11464,,,ATCC 17978,ata,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),HUVEC-C cell line,,,umbilical vein endothelial cell,trimeric autotransporter adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31874074,PubMed,10.1080/21505594.2018.1558693,Virulence. 2019 Dec;10(1):68-81,stephan.goettig@kgu.de,"Ata mediated adhesion and invasion, induced apoptosis and contributed to pathogenicity in vivo.",M Weidensdorfer 2019,2019,1 gene,Weidensdorfer-2019-The Acinetobacter trimeric,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15478,PHI:9898,UniProt,A3M3H0,GenBank,ABO11464,,,ATCC 17978,ata,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),HMEC-1 cell line,,,microvascular endothelial cell line,trimeric autotransporter adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31874074,PubMed,10.1080/21505594.2018.1558693,Virulence. 2019 Dec;10(1):68-81,stephan.goettig@kgu.de,"Ata mediated adhesion and invasion, induced apoptosis and contributed to pathogenicity in vivo.",M Weidensdorfer 2019,2019,1 gene,Weidensdorfer-2019-The Acinetobacter trimeric,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15479,PHI:9898,UniProt,A3M3H0,GenBank,ABO11464,,,ATCC 17978,ata,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),HDMEC-IM cell line,,,dermal microvascular endothelial cell,trimeric autotransporter adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31874074,PubMed,10.1080/21505594.2018.1558693,Virulence. 2019 Dec;10(1):68-81,stephan.goettig@kgu.de,"Ata mediated adhesion and invasion, induced apoptosis and contributed to pathogenicity in vivo.",M Weidensdorfer 2019,2019,1 gene,Weidensdorfer-2019-The Acinetobacter trimeric,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15480,PHI:9898,UniProt,A3M3H0,GenBank,ABO11464,,,ATCC 17978,ata,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,trimeric autotransporter adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31874074,PubMed,10.1080/21505594.2018.1558693,Virulence. 2019 Dec;10(1):68-81,stephan.goettig@kgu.de,"Ata mediated adhesion and invasion, induced apoptosis and contributed to pathogenicity in vivo.",M Weidensdorfer 2019,2019,1 gene,Weidensdorfer-2019-The Acinetobacter trimeric,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15481,PHI:9899,UniProt,Q4WI19,GenBank,EAL87436,,,Af293,RpdA (Afu2g03390),chromosome 2,rpdA promoter exchanged by the xylP promoter,,,,,746128,Aspergillus fumigatus,,AfS35,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,lysine deacetylase,,,,loss of pathogenicity,,,,yes,,,,,,no,xylose,xylose: CHEBI:18222,,,,,promoter mutation,,,YVS,31866965,PubMed,10.3389/fmicb.2019.02773,Front Microbiol. 2019 Dec 4;10:2773,hubertus.haas@i-med.ac.at,The avirulence of rpdAxylP without xylose supplementation compared to the virulence of rpdAxylP with xylose supplementation demonstrated that the xylP promoter allowed control of expression during infection by xylose feeding.,I Bauer 2019,2019,1 gene,Bauer-2019-The Lysine Deacetylase RpdA Is Esse,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15482,PHI:9900,UniProt,J9VX38,GenBank,AFR97946,,,H99,Gpp2 (CNAG_01744),chromosome 11,,,,,,5207,Cryptococcus neoformans,,CNU125,fungal meningitis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,glycerol-3-phosphate phosphatase,,,,reduced virulence,,,,,,,,,,no,NaCl; Congo red; SDS; H2O2; KCl,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; hydrogen peroxide: CHEBI:16240; potassium chloride: CHEBI:32588,,,,,gene mutation; gene complementation,,,YVS,31849880,PubMed,10.3389/fmicb.2019.02728,Front Microbiol. 2019 Nov 26;10:2728,Renata.pascon@gmail.com,"Gpp2Δ strain fails to express virulence factors, as melanin, phospholipase, urease and has virulence attenuation in Galleria mellonella.",K F Martho 2019,2019,1 gene,Martho-2019-The Glycerol Phosphatase Gpp2_ A L,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15483,PHI:9901,UniProt,B8N4E0,GenBank,EQ963473,,,NRRL3357,Aflste20 (AFLA_035530),,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,non-specific serine/threonine protein kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; tert-butyl hydroperoxide; calcofluor white (CFW); SDS,NaCl: CHEBI:26710; tert-butyl hydroperoxide: CHEBI:64090; calcofluor white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31847206,PubMed,10.3390/toxins11120730,Toxins (Basel). 2019 Dec 13;11(12),yjmail2008@fafu.edu.cn,"Aflste20 knockout mutant (ΔAflste20) showed a significant decrease in growth, sporogenesis, sclerotinogenesis, virulence, and infection compared to the WT.",D Li 2019,2019,1 gene,"Li-2019-AflSte20 Regulates Morphogenesis, Stre",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15484,PHI:9901,UniProt,B8N4E0,GenBank,EQ963473,,,NRRL3357,Aflste20 (AFLA_035530),,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,non-specific serine/threonine protein kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; tert-butyl hydroperoxide; calcofluor white (CFW); SDS,NaCl: CHEBI:26710; tert-butyl hydroperoxide: CHEBI:64090; calcofluor white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31847206,PubMed,10.3390/toxins11120730,Toxins (Basel). 2019 Dec 13;11(12),yjmail2008@fafu.edu.cn,"Aflste20 knockout mutant (ΔAflste20) showed a significant decrease in growth, sporogenesis, sclerotinogenesis, virulence, and infection compared to the WT.",D Li 2019,2019,1 gene,"Li-2019-AflSte20 Regulates Morphogenesis, Stre",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15485,PHI:9902,UniProt,A0A384JVF6,GenBank,ATZ54237,,,B05.10,Bcser1 (Bcin10g02530),chromosome BCIN10,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,subtilisin-like protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31963451,PubMed,10.3390/ijms21020603,Int J Mol Sci. 2020 Jan 17;21(2),jiasencheng@mail.hzau.edu.cn,"Subtilisin-like protease Bcser2 is crucial for the sclerotial formation, conidiation, and virulence of B.cinerea",X Liu 2020,2020,2 genes,Liu-2020-The Subtilisin-Like Protease Bcser2 A,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15486,PHI:9903,UniProt,A0A384JPY4,GenBank,ATZ52642,,,B05.10,Bcser2 (Bcin08g02990),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,subtilisin-like protease,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31963451,PubMed,10.3390/ijms21020603,Int J Mol Sci. 2020 Jan 17;21(2),jiasencheng@mail.hzau.edu.cn,"Subtilisin-like protease Bcser2 is crucial for the sclerotial formation, conidiation, and virulence of B.cinerea",X Liu 2020,2020,2 genes,Liu-2020-The Subtilisin-Like Protease Bcser2 A,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15487,PHI:9902,UniProt,A0A384JVF6,GenBank,ATZ54237,,,B05.10,Bcser1 (Bcin10g02530),chromosome BCIN10,,,,,PHI:9903,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,subtilisin-like protease,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31963451,PubMed,10.3390/ijms21020603,Int J Mol Sci. 2020 Jan 17;21(2),jiasencheng@mail.hzau.edu.cn,"Subtilisin-like protease Bcser2 is crucial for the sclerotial formation, conidiation, and virulence of B.cinerea",X Liu 2020,2020,2 genes,Liu-2020-The Subtilisin-Like Protease Bcser2 A,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15488,PHI:9903,UniProt,A0A384JPY4,GenBank,ATZ52642,,,B05.10,Bcser2 (Bcin08g02990),chromosome BCIN08,,,,,PHI:9902,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,subtilisin-like protease,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31963451,PubMed,10.3390/ijms21020603,Int J Mol Sci. 2020 Jan 17;21(2),jiasencheng@mail.hzau.edu.cn,"Subtilisin-like protease Bcser2 is crucial for the sclerotial formation, conidiation, and virulence of B.cinerea",X Liu 2020,2020,2 genes,Liu-2020-The Subtilisin-Like Protease Bcser2 A,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15489,PHI:9902,UniProt,A0A384JVF6,GenBank,ATZ54237,,,B05.10,Bcser1 (Bcin10g02530),chromosome BCIN10,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,subtilisin-like protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31963451,PubMed,10.3390/ijms21020603,Int J Mol Sci. 2020 Jan 17;21(2),jiasencheng@mail.hzau.edu.cn,"Subtilisin-like protease Bcser2 is crucial for the sclerotial formation, conidiation, and virulence of B.cinerea",X Liu 2020,2020,2 genes,Liu-2020-The Subtilisin-Like Protease Bcser2 A,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15490,PHI:9903,UniProt,A0A384JPY4,GenBank,ATZ52642,,,B05.10,Bcser2 (Bcin08g02990),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,subtilisin-like protease,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31963451,PubMed,10.3390/ijms21020603,Int J Mol Sci. 2020 Jan 17;21(2),jiasencheng@mail.hzau.edu.cn,"Subtilisin-like protease Bcser2 is crucial for the sclerotial formation, conidiation, and virulence of B.cinerea",X Liu 2020,2020,2 genes,Liu-2020-The Subtilisin-Like Protease Bcser2 A,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15491,PHI:9902,UniProt,A0A384JVF6,GenBank,ATZ54237,,,B05.10,Bcser1 (Bcin10g02530),chromosome BCIN10,,,,,PHI:9903,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,subtilisin-like protease,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31963451,PubMed,10.3390/ijms21020603,Int J Mol Sci. 2020 Jan 17;21(2),jiasencheng@mail.hzau.edu.cn,"Subtilisin-like protease Bcser2 is crucial for the sclerotial formation, conidiation, and virulence of B.cinerea",X Liu 2020,2020,2 genes,Liu-2020-The Subtilisin-Like Protease Bcser2 A,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15492,PHI:9903,UniProt,A0A384JPY4,GenBank,ATZ52642,,,B05.10,Bcser2 (Bcin08g02990),chromosome BCIN08,,,,,PHI:9902,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,subtilisin-like protease,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31963451,PubMed,10.3390/ijms21020603,Int J Mol Sci. 2020 Jan 17;21(2),jiasencheng@mail.hzau.edu.cn,"Subtilisin-like protease Bcser2 is crucial for the sclerotial formation, conidiation, and virulence of B.cinerea",X Liu 2020,2020,2 genes,Liu-2020-The Subtilisin-Like Protease Bcser2 A,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15493,PHI:9904,,no data found,,,,,,PsYPK1,,,,PsGPA1,UniProt: B2ZFL2; GenBank: ACD03826,,67593,Phytophthora sojae,1094619,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Hefeng 47,,,seedling,serine/threonine protein kinase,,,,reduced virulence,,,,,,,reduced,reduced,,no,rapamycin,rapamycin: CHEBI:68481,,,,,gene deletion: full; gene complementation,,,YVS,31961913,PubMed,10.1371/journal.ppat.1008138,PLoS Pathog. 2020 Jan 21;16(1):e1008138,wangyc@njau.edu.cn,"Deletion of PsYPK1 resulted in a pronounced reduction in the production of sporangia and oospores, in mycelial growth on nutrient poor medium, and in virulence.",M Qiu 2020,2020,1 gene,Qiu-2020-G protein alpha subunit suppresses sp,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15494,PHI:9905,UniProt,A0A1D8PNL1,GenBank,AOW29716,,,SC5314,Mig1,chromosome 5,,,,,,5476,Candida albicans,,CW542,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,transcriptional repressor,,,glucose repression pathway,unaffected pathogenicity,,,,,,,,reduced,,no,caspofungin; calcofluor white; fluconazole,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,YVS,31961865,PubMed,10.1371/journal.pgen.1008582,PLoS Genet. 2020 Jan 21;16(1):e1008582,Aaron.Mitchell@uga.edu,Mig1 and Mig2 were redundant for major biological functions and indicate that Mig1 and Mig2 were required for pathogenicity-associated phenotypes.,K Lagree 2020,2020,2 genes,Lagree-2020-Roles of Candida albicans Mig1 and,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15495,PHI:9906,UniProt,Q5A5S3,,,,,,Mig2,,,,,,,5476,Candida albicans,,CW542,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,transcriptional repressor,,,glucose repression pathway,unaffected pathogenicity,,,,,,,,wild type,,no,caspofungin; calcofluor white; fluconazole,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,YVS,31961865,PubMed,10.1371/journal.pgen.1008582,PLoS Genet. 2020 Jan 21;16(1):e1008582,Aaron.Mitchell@uga.edu,Mig1 and Mig2 were redundant for major biological functions and indicate that Mig1 and Mig2 were required for pathogenicity-associated phenotypes.,K Lagree 2020,2020,2 genes,Lagree-2020-Roles of Candida albicans Mig1 and,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15496,PHI:9905,UniProt,A0A1D8PNL1,GenBank,AOW29716,,,SC5314,Mig1,chromosome 2,,,,,PHI:9906,5476,Candida albicans,,CW542,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,transcriptional repressor,,,glucose repression pathway,reduced virulence,,,,,,,,reduced,,no,caspofungin; calcofluor white; fluconazole,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,YVS,31961865,PubMed,10.1371/journal.pgen.1008582,PLoS Genet. 2020 Jan 21;16(1):e1008582,Aaron.Mitchell@uga.edu,Mig1 and Mig2 were redundant for major biological functions and indicate that Mig1 and Mig2 were required for pathogenicity-associated phenotypes.,K Lagree 2020,2020,2 genes,Lagree-2020-Roles of Candida albicans Mig1 and,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15497,PHI:9906,UniProt,Q5A5S3,,,,,,Mig2,,,,,,PHI:9905,5476,Candida albicans,,CW542,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,transcriptional repressor,,,glucose repression pathway,reduced virulence,,,,,,,,reduced,,no,caspofungin; calcofluor white; fluconazole,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,YVS,31961865,PubMed,10.1371/journal.pgen.1008582,PLoS Genet. 2020 Jan 21;16(1):e1008582,Aaron.Mitchell@uga.edu,Mig1 and Mig2 were redundant for major biological functions and indicate that Mig1 and Mig2 were required for pathogenicity-associated phenotypes.,K Lagree 2020,2020,2 genes,Lagree-2020-Roles of Candida albicans Mig1 and,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15498,PHI:9905,UniProt,A0A1D8PNL1,GenBank,AOW29716,,,SC5314,Mig1,chromosome 2,,,,,,5476,Candida albicans,,CW542,disseminated candidiasis,primates,9606,Homo sapiens (related: human),HUVEC-C cell line,,,umbilical vein endothelial cell,transcriptional repressor,,,glucose repression pathway,unaffected pathogenicity,,,,,,,,reduced,,no,caspofungin; calcofluor white; fluconazole,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,YVS,31961865,PubMed,10.1371/journal.pgen.1008582,PLoS Genet. 2020 Jan 21;16(1):e1008582,Aaron.Mitchell@uga.edu,Mig1 and Mig2 were redundant for major biological functions and indicate that Mig1 and Mig2 were required for pathogenicity-associated phenotypes.,K Lagree 2020,2020,2 genes,Lagree-2020-Roles of Candida albicans Mig1 and,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15499,PHI:9906,UniProt,Q5A5S3,,,,,,Mig2,,,,,,,5476,Candida albicans,,CW542,disseminated candidiasis,primates,9606,Homo sapiens (related: human),HUVEC-C cell line,,,umbilical vein endothelial cell,transcriptional repressor,,,glucose repression pathway,unaffected pathogenicity,,,,,,,,wild type,,no,caspofungin; calcofluor white; fluconazole,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,YVS,31961865,PubMed,10.1371/journal.pgen.1008582,PLoS Genet. 2020 Jan 21;16(1):e1008582,Aaron.Mitchell@uga.edu,Mig1 and Mig2 were redundant for major biological functions and indicate that Mig1 and Mig2 were required for pathogenicity-associated phenotypes.,K Lagree 2020,2020,2 genes,Lagree-2020-Roles of Candida albicans Mig1 and,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15500,PHI:9905,UniProt,A0A1D8PNL1,GenBank,AOW29716,,,SC5314,Mig1,chromosome 2,,,,,PHI:9906,5476,Candida albicans,,CW542,disseminated candidiasis,primates,9606,Homo sapiens (related: human),HUVEC-C cell line,,,umbilical vein endothelial cell,transcriptional repressor,,,glucose repression pathway,reduced virulence,,,,,,,,reduced,,no,caspofungin; calcofluor white; fluconazole,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,YVS,31961865,PubMed,10.1371/journal.pgen.1008582,PLoS Genet. 2020 Jan 21;16(1):e1008582,Aaron.Mitchell@uga.edu,Mig1 and Mig2 were redundant for major biological functions and indicate that Mig1 and Mig2 were required for pathogenicity-associated phenotypes.,K Lagree 2020,2020,2 genes,Lagree-2020-Roles of Candida albicans Mig1 and,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15501,PHI:9906,UniProt,Q5A5S3,,,,,,Mig2,,,,,,PHI:9905,5476,Candida albicans,,CW542,disseminated candidiasis,primates,9606,Homo sapiens (related: human),HUVEC-C cell line,,,umbilical vein endothelial cell,transcriptional repressor,,,glucose repression pathway,reduced virulence,,,,,,,,reduced,,no,caspofungin; calcofluor white; fluconazole,caspofungin: CHEBI:474180; calcofluor white (CFW): CHEBI:50011; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,YVS,31961865,PubMed,10.1371/journal.pgen.1008582,PLoS Genet. 2020 Jan 21;16(1):e1008582,Aaron.Mitchell@uga.edu,Mig1 and Mig2 were redundant for major biological functions and indicate that Mig1 and Mig2 were required for pathogenicity-associated phenotypes.,K Lagree 2020,2020,2 genes,Lagree-2020-Roles of Candida albicans Mig1 and,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15502,PHI:9907,UniProt,Q55996,GenBank,AAQ19849,,,SS2-1,SLY,,,,,,,1307,Streptococcus suis,,,meningitis; septicemia; arthritis; pneumonia (pig),primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,thiol-activated cytolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31905867,PubMed,10.3390/pathogens9010033,Pathogens. 2019 Dec 30;9(1). pii: E33,peter.valentin@tiho-hannover.de,"HEp-2 cells were most susceptible, whereas primary epithelial cells were hardly affected by the toxin. laryngeal epithelial cells",D Votsch 2019,2019,1 gene,"Votsch-2019-Membrane Binding, Cellular Cholest",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15503,PHI:9907,UniProt,Q55996,GenBank,AAQ19849,,,SS2-1,SLY,,,,,,,1307,Streptococcus suis,,,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),NPTr cell line,,,tracheal epithelium,thiol-activated cytolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31905867,PubMed,10.3390/pathogens9010033,Pathogens. 2019 Dec 30;9(1). pii: E33,peter.valentin@tiho-hannover.de,"HEp-2 cells were most susceptible, whereas primary epithelial cells were hardly affected by the toxin.newborn pig tracheal epithelial cells",D Votsch 2019,2019,1 gene,"Votsch-2019-Membrane Binding, Cellular Cholest",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15504,PHI:9907,UniProt,Q55996,GenBank,AAQ19849,,,SS2-1,SLY,,,,,,,1307,Streptococcus suis,,,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),hTERT-PTECs cell line,,,tracheal epithelium,thiol-activated cytolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31905867,PubMed,10.3390/pathogens9010033,Pathogens. 2019 Dec 30;9(1). pii: E33,peter.valentin@tiho-hannover.de,"HEp-2 cells were most susceptible, whereas primary epithelial cells were hardly affected by the toxin. primary porcine tracheal epithelial cells",D Votsch 2019,2019,1 gene,"Votsch-2019-Membrane Binding, Cellular Cholest",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15505,PHI:9907,UniProt,Q55996,GenBank,AAQ19849,,,SS2-1,SLY,,,,,,,1307,Streptococcus suis,,,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),hTERT-PBEC cell line,,,bronchial epithelial cell line,thiol-activated cytolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31905867,PubMed,10.3390/pathogens9010033,Pathogens. 2019 Dec 30;9(1). pii: E33,peter.valentin@tiho-hannover.de,"HEp-2 cells were most susceptible, whereas primary epithelial cells were hardly affected by the toxin. primary porcine bronchial epithelial cells",D Votsch 2019,2019,1 gene,"Votsch-2019-Membrane Binding, Cellular Cholest",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15506,PHI:9907,UniProt,Q55996,GenBank,AAQ19849,,,SS2-1,SLY,,,,,,,1307,Streptococcus suis,,,meningitis; septicemia; arthritis; pneumonia (pig),primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,thiol-activated cytolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31905867,PubMed,10.3390/pathogens9010033,Pathogens. 2019 Dec 30;9(1). pii: E33,peter.valentin@tiho-hannover.de,"HEp-2 cells were most susceptible, whereas primary epithelial cells were hardly affected by the toxin. laryngeal epithelial cells",D Votsch 2019,2019,1 gene,"Votsch-2019-Membrane Binding, Cellular Cholest",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15507,PHI:9907,UniProt,Q55996,GenBank,AAQ19849,,,SS2-1,SLY,,,,,,,1307,Streptococcus suis,,,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),NPTr cell line,,,tracheal epithelium,thiol-activated cytolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31905867,PubMed,10.3390/pathogens9010033,Pathogens. 2019 Dec 30;9(1). pii: E33,peter.valentin@tiho-hannover.de,"HEp-2 cells were most susceptible, whereas primary epithelial cells were hardly affected by the toxin.newborn pig tracheal epithelial cells",D Votsch 2019,2019,1 gene,"Votsch-2019-Membrane Binding, Cellular Cholest",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15508,PHI:9907,UniProt,Q55996,GenBank,AAQ19849,,,SS2-1,SLY,,,,,,,1307,Streptococcus suis,,,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),hTERT-PTECs cell line,,,tracheal epithelium,thiol-activated cytolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31905867,PubMed,10.3390/pathogens9010033,Pathogens. 2019 Dec 30;9(1). pii: E33,peter.valentin@tiho-hannover.de,"HEp-2 cells were most susceptible, whereas primary epithelial cells were hardly affected by the toxin. primary porcine tracheal epithelial cells",D Votsch 2019,2019,1 gene,"Votsch-2019-Membrane Binding, Cellular Cholest",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15509,PHI:9907,UniProt,Q55996,GenBank,AAQ19849,,,SS2-1,SLY,,,,,,,1307,Streptococcus suis,,,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),hTERT-PBEC cell line,,,bronchial epithelial cell line,thiol-activated cytolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31905867,PubMed,10.3390/pathogens9010033,Pathogens. 2019 Dec 30;9(1). pii: E33,peter.valentin@tiho-hannover.de,"HEp-2 cells were most susceptible, whereas primary epithelial cells were hardly affected by the toxin.primary porcine bronchial epithelial cells",D Votsch 2019,2019,1 gene,"Votsch-2019-Membrane Binding, Cellular Cholest",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15510,PHI:9908,UniProt,I1S4P6,GenBank,CEF72701,,,PH-1,Rad50 (FGSG_11814),,,,,,,5518,Fusarium graminearum,229533,PH-1,head blight (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,spikelet,unnamed protein product,,,DON biosynthesis,reduced virulence,,,,,,reduced,reduced,reduced,,no,camptothecin (CPT); methyl methanesulfonate (MMS); hydroxyurea (HU); 4-nitroquinoline (4-NQ); SDS; Congo red (CR); calcofluor white (CFW),camptothecin (CPT): CHEBI:27656; methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea (HU): CHEBI:44423; 4-nitroquinoline (4-NQ) CAS no.: CAS:3741-15-9; SDS: CHEBI:8984; Congo red (CR): CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,31998262,PubMed,10.3389/fmicb.2019.02970,Front. Microbiol. 10:2970,chenlii@ahau.edu.cn,"The FgRad50 deletion mutant (ΔfgRad50) exhibited defective vegetative growth, asexual/sexual development and virulence, as well as disrupted deoxynivalenol biosynthesis.",C Zhang 2019,2019,1 gene,Zhang-2019-FgRad50 Regulates Fungal Developmen,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15511,PHI:9909,UniProt,Q04IN8,GenBank,ABJ53672,,,D39,ply,,,,,,,1313,Streptococcus pneumoniae,,519/43 ST 5316,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung; blood,pneumolysin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: partial,,,YVS,31996316,PubMed,10.1016/j.micpath.2020.103999,Microb Pathog. 2020 Jan 26;141:103999,vanessa.terra@lshtm.ac.uk,"When mice were infected intranasally with the mutant 519/43Δply there was no significant difference between the load of bacteria in lungs and blood when compared to the wild type 519/43, when mice were infected intraperitoneally there were significantly fewer bacteria recovered from blood for the mutant 519/43Δplystrain.",VS Terra 2020,2020,1 gene,Terra-2020-Construction of a pneumolysin defic,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15512,PHI:9910,UniProt,G1XQC8,GenBank,EGX44472,,,ATCC 24927,ime2 (AOL_s00188g140),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,protein kinase domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,hydrogen peroxide; menadione; sodium chloride; sorbitol; sodium dodecyl sulfate; Congo red,hydrogen peroxide: CHEBI:16240; menadione: CHEBI:28869; sodium chloride: CHEBI:26710; sorbitol: CHEBI:17924; sodium dodecyl sulfate: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene disruption,,,YVS,31993040,PubMed,10.3389/fmicb.2019.03065,Front Microbiol. 2020 Jan 14;10:3065,jinkui960@ynu.edu.cn,Ime2 was critical for osmotic-pressure adaptation in A. oligospora. Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.,M Xie 2019,2019,1 gene,Xie-2019-Protein Kinase Ime2 Is Required for M,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15513,PHI:9911,UniProt,G2Y8F7,GenBank,CCD48885,,,T4,Hpt,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,histidine phosphotransfer protein,,,high-osmolarity glycerol (HOG) transduction pathway,reduced virulence,,,no,,,wild type,,reduced,,no,sodium chloride; potassium chloride; hydrogen peroxide; congo red; caffeine; iprodione; triadimefon,sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; hydrogen peroxide: CHEBI:16240; Congo red: CHEBI:34653; caffeine: CHEBI:27732; iprodione: CHEBI:28909; triadimefon: CHEBI:9665,,,,,gene mutation,,,YVS,31969871,PubMed,10.3389/fmicb.2019.02965,Front Microbiol. 2020 Jan 8;10:2965,wliang1@qau.edu.cn,"The mutant strain ΔBcHPt + BcHptK161Q-GFP, which exhibited a slower growth rate; lower pathogenicity; higher sensitivity to multiple stresses.",Q Yang 2019,2019,1 gene,Yang-2019-Acetylation of BcHpt Lysine 161 Regu,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15514,PHI:9912,UniProt,B8NSN6,GenBank,EED46934,,,NRRL3357,AreA (AFLA_049870),,,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::AfpyrG ΔniaD),infection,eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,GATA transcriptional activator,,,aflatoxin B1 production,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,sodium chloride; potassium chloride; hydrogen peroxide; congo red; calcofluor white,sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; hydrogen peroxide: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,31835504,PubMed,10.3390/toxins11120718,Toxins (Basel). 2019 Dec 10;11(12). pii: E718,wshmail@m.fafu.edu.cn,The ΔareA strain was unable to efficiently utilize secondary nitrogen sources for growth of A. Flavus.,O E Fasoyin 2019,2019,1 gene,"Fasoyin-2019-Regulation of Morphology, Aflatox",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15515,PHI:9912,UniProt,B8NSN6,GenBank,EED46934,,,NRRL3357,AreA (AFLA_049870),,,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::AfpyrG ΔniaD),infection,eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,GATA transcriptional activator,,,aflatoxin B1 production,unaffected pathogenicity,,,,,,wild type,,wild type,,no,sodium chloride; potassium chloride; hydrogen peroxide; congo red; calcofluor white,sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; hydrogen peroxide: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31835504,PubMed,10.3390/toxins11120718,Toxins (Basel). 2019 Dec 10;11(12). pii: E718,wshmail@m.fafu.edu.cn,The ΔareA strain was unable to efficiently utilize secondary nitrogen sources for growth of A. Flavus.,O E Fasoyin 2019,2019,1 gene,"Fasoyin-2019-Regulation of Morphology, Aflatox",BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15516,PHI:9913,UniProt,B8N3S2,GenBank,EED55884,,,NRRL3357,AflBck1,,,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::AfpyrG ΔniaD),infection,eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,cell wall integrity-related MAP kinase kinase kinase,,,mitogen-activated protein kinase pathway,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,sorbitol; sodium dodecyl sulfate; hydrogen peroxide; congo red; calcofluor white,sorbitol: CHEBI:17924; sodium dodecyl sulfate: CHEBI:8984; hydrogen peroxide: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,31922927,PubMed,10.1094/MPMI-11-19-0327-R,Mol Plant Microbe Interact. 2020 Jan 10,wshyyl@sina.com,"ΔAflBck1 displayed an enhanced ability to produce aflatoxin, a potential carcinogenic mycotoxin.",F Zhang 2020,2020,1 gene,Zhang-2020-A cell wall integrity-related MAP k,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15517,PHI:9914,UniProt,Q0P8C5,GenBank,CAL35599,,,NCTC 11168,Cj1492c,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,gastroenteritis,primates,9606,Homo sapiens (related: human),HT-29/B6 cell line,,,intestinal epithelial cell,two-component sensor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,32064001,PubMed,10.1186/s13099-020-00347-8,Gut Pathog. 2020 Feb 11;12:8,greta.goelz@fu-berlin.de,"Both mutants showed significantly diminished intracellular survival rates compared to the wild type, however no difference in host cell viability and induction of the pro-inflammatory chemokine IL-8 were determined between both mutants and the wild type.",D Xi 2020,2020,2 genes,Xi-2020-Campylobacter jejuni genes Cj1492c and,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15518,PHI:9915,UniProt,Q0P8B1,GenBank,CAL35613,,,NCTC 11168,Cj1507c,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,gastroenteritis,primates,9606,Homo sapiens (related: human),HT-29/B6 cell line,,,intestinal epithelial cell,regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,32064001,PubMed,10.1186/s13099-020-00347-8,Gut Pathog. 2020 Feb 11;12:8,greta.goelz@fu-berlin.de,"Both mutants showed significantly diminished intracellular survival rates compared to the wild type, however no difference in host cell viability and induction of the pro-inflammatory chemokine IL-8 were determined between both mutants and the wild type.",D Xi 2020,2020,2 genes,Xi-2020-Campylobacter jejuni genes Cj1492c and,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15519,PHI:9916,UniProt,A6VF14,GenBank,ABR81513,,,PA7,dksA1,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,RNA polymerase-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32047111,PubMed,10.1074/jbc.RA119.011692,J Biol Chem. 2020 Feb 11. pii: jbc.RA119.011692,sangsun_yoon@yuhs.ac,"Mice infected with PAO1 and ΔdksA2 mutants were affected at a significantly faster rate, whereas mice infected with ΔdksA1 and ΔdksA1ΔdksA2 mutants died slowly and survived for up to 22 hours.",K B Min 2020,2020,2 genes,Min-2020-Transcriptome analysis reveals that t,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15520,PHI:9917,UniProt,A6VCH8,GenBank,ABR86497,,,PA7,dksA2,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,RNA polymerase-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32047111,PubMed,10.1074/jbc.RA119.011692,J Biol Chem. 2020 Feb 11. pii: jbc.RA119.011692,sangsun_yoon@yuhs.ac,"Mice infected with PAO1 and ΔdksA2 mutants were affected at a significantly faster rate, whereas mice infected with ΔdksA1 and ΔdksA1ΔdksA2 mutants died slowly and survived for up to 22 hours.",K B Min 2020,2020,2 genes,Min-2020-Transcriptome analysis reveals that t,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15521,PHI:9916,UniProt,A6VF14,GenBank,ABR81513,,,PA7,dksA1,,,,,,PHI:9917,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,RNA polymerase-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32047111,PubMed,10.1074/jbc.RA119.011692,J Biol Chem. 2020 Feb 11. pii: jbc.RA119.011692,sangsun_yoon@yuhs.ac,"Mice infected with PAO1 and ΔdksA2 mutants were affected at a significantly faster rate, whereas mice infected with ΔdksA1 and ΔdksA1ΔdksA2 mutants died slowly and survived for up to 22 hours.",K B Min 2020,2020,2 genes,Min-2020-Transcriptome analysis reveals that t,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15522,PHI:9917,UniProt,A6VCH8,GenBank,ABR86497,,,PA7,dksA2,,,,,,PHI:9916,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,RNA polymerase-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32047111,PubMed,10.1074/jbc.RA119.011692,J Biol Chem. 2020 Feb 11. pii: jbc.RA119.011692,sangsun_yoon@yuhs.ac,"Mice infected with PAO1 and ΔdksA2 mutants were affected at a significantly faster rate, whereas mice infected with ΔdksA1 and ΔdksA1ΔdksA2 mutants died slowly and survived for up to 22 hours.",K B Min 2020,2020,2 genes,Min-2020-Transcriptome analysis reveals that t,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15523,PHI:9918,UniProt,P9WFK3,GenBank,CCP43241,,,H37Rv,HadD (Rv0504c),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C.B-17/Icr<scid>,,,lung; spleen,dehydratase protein,,,,reduced virulence,,,,,,,,,,no,rifampicin,rifampicin: CHEBI:28077,,,,,gene deletion: full; gene complementation,,,YVS,32034201,PubMed,10.1038/s41598-020-58967-8,Sci Rep. 2020 Feb 7;10(1):2112,annaik.quemard@ipbs.fr,"Phenotyping of Mtb hadD deletion mutant revealed the influence of HadDMtb on the planktonic growth, colony morphology and biofilm structuration, as well as on low temperature tolerance.",C Lefebvre 2020,2020,1 gene,Lefebvre-2020-Discovery of a novel dehydratase,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15524,PHI:9918,UniProt,P9WFK3,GenBank,CCP43241,,,H37Rv,HadD (Rv0504c),,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C.B-17/Icr<scid>,,,lung; spleen,dehydratase protein,,,,unaffected pathogenicity,,,,,,,,,,no,rifampicin,rifampicin: CHEBI:28077,,,,,heterologous expression,,,YVS,32034201,PubMed,10.1038/s41598-020-58967-8,Sci Rep. 2020 Feb 7;10(1):2112,annaik.quemard@ipbs.fr,"Phenotyping of Mtb hadD deletion mutant revealed the influence of HadDMtb on the planktonic growth, colony morphology and biofilm structuration, as well as on low temperature tolerance.",C Lefebvre 2020,2020,1 gene,Lefebvre-2020-Discovery of a novel dehydratase,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15525,PHI:9919,UniProt,P9WPD1,GenBank,CCP43114,,,H37Rv,clpB,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,chaperone protein,,,MAPK and NF-κB pathways,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32014406,PubMed,10.1016/j.ijmm.2020.151402,Int J Med Microbiol. 2020 Jan 23:151402,janendra@nii.ac.in,"The disruption of ClpB resulted in aberrant cellular morphology, impaired biofilm formation and reduced infectivity of Mtb ex vivo.",P Tripathi 2020,2020,1 gene,Tripathi-2020-ClpB is an essential stress regu,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15526,PHI:9920,UniProt,G4NGH0,GenBank,EHA47127,,,70-15,ZFC3 (MGG_04317),chromosome 6,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. JJ88,,,leaf,C3HC type zinc-finger protein,,,,increased virulence (hypervirulence),,,,,,increased,,,,no,H2O2; Congo red; SDS,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32000669,PubMed,10.1186/s12866-020-1711-4,BMC Microbiol. 2020 Jan 30;20(1):23,zhang_sh@jlu.edu.cn,The knock-out strain showed more melanin accumulation displaying faster hypha infiltration in host rice.,S Liu 2020,2020,1 gene,Liu-2020-The C3HC type zinc-finger protein (ZF,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15527,PHI:9920,UniProt,G4NGH0,GenBank,EHA47127,,,70-15,ZFC3 (MGG_04317),chromosome 6,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,C3HC type zinc-finger protein,,,,increased virulence (hypervirulence),,,,,,increased,,,,no,H2O2; Congo red; SDS,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32000669,PubMed,10.1186/s12866-020-1711-4,BMC Microbiol. 2020 Jan 30;20(1):23,zhang_sh@jlu.edu.cn,The knock-out strain showed more melanin accumulation displaying faster hypha infiltration in host rice.,S Liu 2020,2020,1 gene,Liu-2020-The C3HC type zinc-finger protein (ZF,BATCH_099A,2020-02-01,MC,,,,,,,,,,,,,
,,Record 15528,PHI:9921,UniProt,no data found,GenBank,OFA14088,,,OB15,liaR,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,daptomycin,daptomycin: CHEBI:600103,,,,,gene deletion: full,,,YVS,31818937,PubMed,10.1073/pnas.1916037116,Proc Natl Acad Sci U S A. 2019 Dec 9,Cesar.Arias@uth.tmc.edu,"Host gene alteration data available for Δpmk-1. Addition of exogenous N terminus of LiaX did not, however, alter the virulence of OG1RF ΔliaR and TM ΔliaR.",A Khan 2019,2019,2 genes,Khan-2019-Antimicrobial sensing coupled with c,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15529,PHI:9922,UniProt,no data found,GenBank,QIJ68253,,,OB15,liaX,,N terminus of LiaX,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,daptomycin-sensing surface protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,daptomycin,daptomycin: CHEBI:600103,,,,,functional test in host,,,YVS,31818937,PubMed,10.1073/pnas.1916037116,Proc Natl Acad Sci U S A. 2019 Dec 9,Cesar.Arias@uth.tmc.edu,Host gene alteration data available for Δpmk-1. OG1RF and S613 were more virulent on addition of the N terminus of LiaX.,A Khan 2019,2019,2 genes,Khan-2019-Antimicrobial sensing coupled with c,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15530,PHI:9921,UniProt,no data found,GenBank,OFA14088,,,CG_E,liaR,,,,,,PHI:9922,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,daptomycin,daptomycin: CHEBI:600103,,,,,gene deletion: full,,,YVS,31818937,PubMed,10.1073/pnas.1916037116,Proc Natl Acad Sci U S A. 2019 Dec 9,Cesar.Arias@uth.tmc.edu,"Host gene alteration data available for Δpmk-1. Addition of exogenous N terminus of LiaX did not, however, alter the virulence of OG1RF ΔliaR and TM ΔliaR.",A Khan 2019,2019,2 genes,Khan-2019-Antimicrobial sensing coupled with c,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15531,PHI:9922,UniProt,no data found,GenBank,QIJ68253,,,OB15,liaX,,N terminus of LiaX,,,,PHI:9921,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,daptomycin-sensing surface protein,,,,reduced virulence,,,,,,,,,,no,daptomycin,daptomycin: CHEBI:600103,,,,,functional test in host,,,YVS,31818937,PubMed,10.1073/pnas.1916037116,Proc Natl Acad Sci U S A. 2019 Dec 9,Cesar.Arias@uth.tmc.edu,"Host gene alteration data available for Δpmk-1. Addition of exogenous N terminus of LiaX did not, however, alter the virulence of OG1RF ΔliaR and TM ΔliaR.",A Khan 2019,2019,2 genes,Khan-2019-Antimicrobial sensing coupled with c,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15532,PHI:9921,UniProt,no data found,GenBank,OFA14088,,,OB15,liaR,,,,,,,1351,Enterococcus faecalis,699185,S613,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,daptomycin,daptomycin: CHEBI:600103,,,,,gene deletion: full,,,YVS,31818937,PubMed,10.1073/pnas.1916037116,Proc Natl Acad Sci U S A. 2019 Dec 9,Cesar.Arias@uth.tmc.edu,"Host gene alteration data available for Δpmk-1. Addition of exogenous N terminus of LiaX did not, however, alter the virulence of OG1RF ΔliaR and TM ΔliaR.",A Khan 2019,2019,2 genes,Khan-2019-Antimicrobial sensing coupled with c,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15533,PHI:9922,UniProt,no data found,GenBank,QIJ68253,,,OB15,liaX,,N terminus of LiaX,,,,,1351,Enterococcus faecalis,699185,S613,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,daptomycin-sensing surface protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,daptomycin,daptomycin: CHEBI:600103,,,,,functional test in host,,,YVS,31818937,PubMed,10.1073/pnas.1916037116,Proc Natl Acad Sci U S A. 2019 Dec 9,Cesar.Arias@uth.tmc.edu,Host gene alteration data available for Δpmk-1. OG1RF and S613 were more virulent on addition of the N terminus of LiaX.,A Khan 2019,2019,2 genes,Khan-2019-Antimicrobial sensing coupled with c,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15534,PHI:9921,UniProt,no data found,GenBank,OFA14088,,,CG_E,liaR,,,,,,PHI:9922,1351,Enterococcus faecalis,699185,S613,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,daptomycin,daptomycin: CHEBI:600103,,,,,gene deletion: full,,,YVS,31818937,PubMed,10.1073/pnas.1916037116,Proc Natl Acad Sci U S A. 2019 Dec 9,Cesar.Arias@uth.tmc.edu,"Host gene alteration data available for Δpmk-1. Addition of exogenous N terminus of LiaX did not, however, alter the virulence of OG1RF ΔliaR and TM ΔliaR.",A Khan 2019,2019,2 genes,Khan-2019-Antimicrobial sensing coupled with c,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15535,PHI:9922,UniProt,no data found,GenBank,QIJ68253,,,OB15,liaX,,N terminus of LiaX,,,,PHI:9921,1351,Enterococcus faecalis,699185,S613,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,daptomycin-sensing surface protein,,,,reduced virulence,,,,,,,,,,no,daptomycin,daptomycin: CHEBI:600103,,,,,functional test in host,,,YVS,31818937,PubMed,10.1073/pnas.1916037116,Proc Natl Acad Sci U S A. 2019 Dec 9,Cesar.Arias@uth.tmc.edu,"Host gene alteration data available for Δpmk-1. Addition of exogenous N terminus of LiaX did not, however, alter the virulence of OG1RF ΔliaR and TM ΔliaR.",A Khan 2019,2019,2 genes,Khan-2019-Antimicrobial sensing coupled with c,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15536,PHI:9923,UniProt,P0A1C1,GenBank,AAA26541,,,M9OT,Spa47,,"Spa47 K165A, Spa47 E188A, Spa47 R350",,,,,623,Shigella flexneri,198215,2457T,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,oligomerization-activated T3SS ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31978132,PubMed,10.1371/journal.pone.0228227,PLoS One. 2020 Jan 24;15(1):e0228227,nick.dickenson@usu.edu,"The N-terminus of Spa47, and not the ATPase activity, was responsible for incorporation into the injectisome where the mutant strains exhibited a dominant negative effect on T3SS function and Shigella virulence.",J L Burgess 2020,2020,1 gene,Burgess-2020-Dominant negative effects by inac,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15537,PHI:9923,UniProt,P0A1C1,GenBank,AAA26541,,,M9OT,Spa47,,"Spa47 K165A, Spa47 E188A, Spa47 R350",,,,,623,Shigella flexneri,198215,2457T,shigellosis,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,oligomerization-activated T3SS ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31978132,PubMed,10.1371/journal.pone.0228227,PLoS One. 2020 Jan 24;15(1):e0228227,nick.dickenson@usu.edu,"The N-terminus of Spa47, and not the ATPase activity, was responsible for incorporation into the injectisome where the mutant strains exhibited a dominant negative effect on T3SS function and Shigella virulence.",J L Burgess 2020,2020,1 gene,Burgess-2020-Dominant negative effects by inac,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15538,PHI:9923,UniProt,P0A1C1,GenBank,AAA26541,,,M9OT,Spa47,,Spa47 E188A/R350A,,,,,623,Shigella flexneri,198215,2457T,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,oligomerization-activated T3SS ATPase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31978132,PubMed,10.1371/journal.pone.0228227,PLoS One. 2020 Jan 24;15(1):e0228227,nick.dickenson@usu.edu,"The N-terminus of Spa47, and not the ATPase activity, was responsible for incorporation into the injectisome where the mutant strains exhibited a dominant negative effect on T3SS function and Shigella virulence.",J L Burgess 2020,2020,1 gene,Burgess-2020-Dominant negative effects by inac,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15539,PHI:9923,UniProt,P0A1C1,GenBank,AAA26541,,,M9OT,Spa47,,Spa47 E188A/R350A,,,,,623,Shigella flexneri,198215,2457T,shigellosis,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,oligomerization-activated T3SS ATPase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31978132,PubMed,10.1371/journal.pone.0228227,PLoS One. 2020 Jan 24;15(1):e0228227,nick.dickenson@usu.edu,"The N-terminus of Spa47, and not the ATPase activity, was responsible for incorporation into the injectisome where the mutant strains exhibited a dominant negative effect on T3SS function and Shigella virulence.",J L Burgess 2020,2020,1 gene,Burgess-2020-Dominant negative effects by inac,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15540,PHI:9923,UniProt,P0A1C1,GenBank,AAA26541,,,M9OT,Spa47,,,,,,,623,Shigella flexneri,198215,2457T,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,oligomerization-activated T3SS ATPase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31978132,PubMed,10.1371/journal.pone.0228227,PLoS One. 2020 Jan 24;15(1):e0228227,nick.dickenson@usu.edu,"The N-terminus of Spa47, and not the ATPase activity, was responsible for incorporation into the injectisome where the mutant strains exhibited a dominant negative effect on T3SS function and Shigella virulence.",J L Burgess 2020,2020,1 gene,Burgess-2020-Dominant negative effects by inac,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15541,PHI:9923,UniProt,P0A1C1,GenBank,AAA26541,,,M9OT,Spa47,,,,,,,623,Shigella flexneri,198215,2457T,shigellosis,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,oligomerization-activated T3SS ATPase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31978132,PubMed,10.1371/journal.pone.0228227,PLoS One. 2020 Jan 24;15(1):e0228227,nick.dickenson@usu.edu,"The N-terminus of Spa47, and not the ATPase activity, was responsible for incorporation into the injectisome where the mutant strains exhibited a dominant negative effect on T3SS function and Shigella virulence.",J L Burgess 2020,2020,1 gene,Burgess-2020-Dominant negative effects by inac,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15542,PHI:9923,UniProt,P0A1C1,GenBank,AAA26541,,,M9OT,Spa47,,oligomerization deficient and ATPase inactive Spa47 Δ1–79 N-terminal truncation mutant,,,,,623,Shigella flexneri,198215,2457T,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,oligomerization-activated T3SS ATPase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31978132,PubMed,10.1371/journal.pone.0228227,PLoS One. 2020 Jan 24;15(1):e0228227,nick.dickenson@usu.edu,"The N-terminus of Spa47, and not the ATPase activity, was responsible for incorporation into the injectisome where the mutant strains exhibited a dominant negative effect on T3SS function and Shigella virulence.",J L Burgess 2020,2020,1 gene,Burgess-2020-Dominant negative effects by inac,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15543,PHI:9923,UniProt,P0A1C1,GenBank,AAA26541,,,M9OT,Spa47,,oligomerization deficient and ATPase inactive Spa47 Δ1–79 N-terminal truncation mutant,,,,,623,Shigella flexneri,198215,2457T,shigellosis,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,oligomerization-activated T3SS ATPase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31978132,PubMed,10.1371/journal.pone.0228227,PLoS One. 2020 Jan 24;15(1):e0228227,nick.dickenson@usu.edu,"The N-terminus of Spa47, and not the ATPase activity, was responsible for incorporation into the injectisome where the mutant strains exhibited a dominant negative effect on T3SS function and Shigella virulence.",J L Burgess 2020,2020,1 gene,Burgess-2020-Dominant negative effects by inac,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15544,PHI:9924,UniProt,A0A2J9HLA0,GenBank,PNL05296,,,FDAARGOS_346,"bcsQ (yhjQ, BGLU_RS28225)",,,,,,,337,Burkholderia glumae,626418,BGR1,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Milyang 23,,,stem,putative cellulose biosynthetic genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32010117,PubMed,10.3389/fmicb.2019.03090,Front Microbiol. 2020 Jan 17;10:3090,jinwoo@gnu.ac.kr,"Pellicle-defective mutants did not colonize as successfully as the wild-type strain BGR1 in rice plants, which resulted in a significant reduction in virulence.",G Y Kwak 2019,2019,2 genes,Kwak-2019-Quorum Sensing-Independent Cellulase,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15545,PHI:9925,UniProt,A0A2J9HL87,GenBank,PNL05293,,,FDAARGOS_346,bcsC (BGLU_RS28245),,,,,,,337,Burkholderia glumae,626418,BGR1,panicle blight,monocots,4530,Oryza sativa (related: rice),cv. Milyang 23,,,stem,putative cellulose biosynthetic genes,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32010117,PubMed,10.3389/fmicb.2019.03090,Front Microbiol. 2020 Jan 17;10:3090,jinwoo@gnu.ac.kr,"Pellicle-defective mutants did not colonize as successfully as the wild-type strain BGR1 in rice plants, which resulted in a significant reduction in virulence.",G Y Kwak 2019,2019,2 genes,Kwak-2019-Quorum Sensing-Independent Cellulase,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15546,PHI:9926,UniProt,B2HMS6,GenBank,ACC43845,,,M,EspM (MMAR_5438),,,,,,,1781,Mycobacterium marinum,216594,M,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,conserved transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32019792,PubMed,10.1128/mBio.02807-19,mBio. 2020 Feb 4;11(1),pchampio@nd.edu.,"The absence of the espM gene, the ESX-1 system promoted higher levels of macrophage lysis.",K G Sanchez 2020,2020,2 genes,Sanchez-2020-EspM Is a Conserved Transcription,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15547,PHI:9927,UniProt,A0A3E2MUT9,GenBank,RFZ40190,,,Davis1,eccCb1,,,,,,,1781,Mycobacterium marinum,216594,M,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,ESX-1 secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32019792,PubMed,10.1128/mBio.02807-19,mBio. 2020 Feb 4;11(1),pchampio@nd.edu.,Infection with the ΔeccCb1 strain resulted in a significant reduction in macrophage lysis compared to infection with the WT strain.,K G Sanchez 2020,2020,2 genes,Sanchez-2020-EspM Is a Conserved Transcription,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15548,PHI:9928,UniProt,Q4WMK0,GenBank,EAL88814,,,Af293,GliZ (6g09630),chromosome 6,,,,,,746128,Aspergillus fumigatus,,A1160,fungal infection,rodents,10090,Mus musculus (related: house mouse),,,,lung,C6 finger domain transcription factor,,,gliotoxin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,promoter mutation,,,YVS,31817957,PubMed,10.3390/ijms20246192,Int J Mol Sci. 2019 Dec 8;20(24),dcomtrue@korea.ac.kr,"Mutation of the ZafA-binding motifs in GliZ resulted in an increase in the conidial killing activity of human macrophage and neutrophil cells, and virulence was decreased in a murine model.",H Seo 2019,2019,1 gene,Seo-2019-The Role of Zinc in Gliotoxin Biosynt,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15549,PHI:9928,UniProt,Q4WMK0,GenBank,EAL88814,,,Af293,GliZ (6g09630),chromosome 6,,,,,,746128,Aspergillus fumigatus,,A1160,fungal infection,rodents,10090,Mus musculus (related: house mouse),,,,lung,C6 finger domain transcription factor,,,gliotoxin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31817957,PubMed,10.3390/ijms20246192,Int J Mol Sci. 2019 Dec 8;20(24),dcomtrue@korea.ac.kr,"Mutation of the ZafA-binding motifs resulted in an increase in the conidial killing activity of human macrophage and neutrophil cells, and virulence was decreased in a murine model.",H Seo 2019,2019,1 gene,Seo-2019-The Role of Zinc in Gliotoxin Biosynt,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15550,PHI:9928,UniProt,Q4WMK0,GenBank,EAL88814,,,Af293,GliZ (6g09630),chromosome 6,,,,,,746128,Aspergillus fumigatus,,A1160,fungal infection,primates,9606,Homo sapiens (related: human),HL-60 cell line,,,macrophage,C6 finger domain transcription factor,,,gliotoxin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,promoter mutation,,,YVS,31817957,PubMed,10.3390/ijms20246192,Int J Mol Sci. 2019 Dec 8;20(24),dcomtrue@korea.ac.kr,"Mutation of the ZafA-binding motifs resulted in an increase in the conidial killing activity of human macrophage and neutrophil cells, and virulence was decreased in a murine model.",H Seo 2019,2019,1 gene,Seo-2019-The Role of Zinc in Gliotoxin Biosynt,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15551,PHI:9928,UniProt,Q4WMK0,GenBank,EAL88814,,,Af293,GliZ (6g09630),chromosome 6,,,,,,746128,Aspergillus fumigatus,,A1160,fungal infection,primates,9606,Homo sapiens (related: human),HL-60 cell line,,,neutrophil,C6 finger domain transcription factor,,,gliotoxin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,promoter mutation,,,YVS,31817957,PubMed,10.3390/ijms20246192,Int J Mol Sci. 2019 Dec 8;20(24),dcomtrue@korea.ac.kr,"Mutation of the ZafA-binding motifs resulted in an increase in the conidial killing activity of human macrophage and neutrophil cells, and virulence was decreased in a murine model.",H Seo 2019,2019,1 gene,Seo-2019-The Role of Zinc in Gliotoxin Biosynt,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15552,PHI:9929,UniProt,W7MR09,GenBank,EWG50183,,,7600,Myo1,chromosome 1,"FvMyo1 S73L, FvMyo1 E276K",,,,,117187,Fusarium verticillioides,334819,7600,ear rot,monocots,4577,Zea mays (related: maize),,,,stem,myosin-1,,,,unaffected pathogenicity,,,,,,,,,,no,carbendazim; tebuconazole; phenamacril,carbendazim: CHEBI:3392; tebuconazole: CHEBI:81781; phenamacril: CAS:3336-69-4,,,,,gene mutation,,,YVS,31961255,PubMed,10.1094/PHYTO-11-19-0407-R,Phytopathology. 2020 Jan 21,changjun-chen@njau.edu.cn,"Compared with the wild-type strain 7600, the ultraviolet (UV) induced resistant mutants showed a significant decrease in mycelial growth, conidiation and virulence.",W Ren 2020,2020,1 gene,Ren-2020-Characterization of the resistance me,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15553,PHI:9929,UniProt,W7MR09,GenBank,EWG50183,,,7600,Myo1,chromosome 1,codon175 (TCA) for serine was changed to a codon (TTA) for leucine; codon276 (GAG) for glutamic acid was changed to a codon (AAG) for lysine,,,,,117187,Fusarium verticillioides,334819,7600,ear rot,monocots,4577,Zea mays (related: maize),,,,stem,myosin-1,,,,reduced virulence,,,,,,,,,,no,carbendazim; tebuconazole; phenamacril,carbendazim: CHEBI:3392; tebuconazole: CHEBI:81781; phenamacril: CAS:3336-69-4,,,,,gene mutation,,,YVS,31961255,PubMed,10.1094/PHYTO-11-19-0407-R,Phytopathology. 2020 Jan 21,changjun-chen@njau.edu.cn,"Compared with the wild-type strain 7600, the ultraviolet (UV) induced resistant mutants showed a significant decrease in mycelial growth, conidiation and virulence.",W Ren 2020,2020,1 gene,Ren-2020-Characterization of the resistance me,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15554,PHI:9930,UniProt,A0A125SDP7,GenBank,AME21449,,,21603,VopC,,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestinal mucosa; liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31848276,PubMed,10.1128/mBio.02608-19,mBio. 2019 Dec 17;10(6),bvallance@cw.bc.ca,"A strain expressing the T3SS2 but lacking VopC (POR2ΔvopC), a T3SS2 effector implicated in epithelial cell invasion in culture, was strongly attenuated in invading the intestinal mucosa and in causing gastroenteritis, although infection with this mutant resulted in more pathology than the ΔT3SS2 strain.",H Yang 2019,2019,1 gene,Yang-2019-A Novel Mouse Model of Enteric Vibri,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15555,PHI:9931,UniProt,A0A069PXM6,GenBank,CEI16009,,,MH19,lpxO1,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,blood,aspartyl/asparaginyl beta-hydroxylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,sodium dodecyl sulphate (SDS); colistin; novobiocin; ciprofloxacin; imipenem; rifampicin; streptomycin; tobramycin; erythromycin,sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; novobiocin: CHEBI:28368; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; rifampicin: CHEBI:28077; streptomycin: CHEBI:17076; tobramycin: CHEBI:28864; erythromycin: CHEBI:48923,,,,,gene deletion: full; gene complementation,,,YVS,31835493,PubMed,10.3390/pathogens8040291,Pathogens. 2019 Dec 10;8(4),francesco.imperi@uniroma3.it,"None of the lpxO mutants showed significant dierences in survival in whole human blood with respect to their parental strain, indicating that hydroxylation in the lipid A secondary chains did not contribute to blood resistance in P. aeruginosa.",A Lo Sciuto 2019,2019,2 genes,Lo Sciuto-2019-Genetic Basis and Physiological,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15556,PHI:9932,UniProt,Q9I522,GenBank,AE004528_3,,,PAO1,lpxO2,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,blood,lipopolysaccharide biosynthetic protein LpxO2,,,,unaffected pathogenicity,,,,,,,,wild type,,no,sodium dodecyl sulphate (SDS); colistin; novobiocin; ciprofloxacin; imipenem; rifampicin; streptomycin; tobramycin; erythromycin,sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; novobiocin: CHEBI:28368; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; rifampicin: CHEBI:28077; streptomycin: CHEBI:17076; tobramycin: CHEBI:28864; erythromycin: CHEBI:48923,,,,,gene deletion: full; gene complementation,,,YVS,31835493,PubMed,10.3390/pathogens8040291,Pathogens. 2019 Dec 10;8(4),francesco.imperi@uniroma3.it,"None of the lpxO mutants showed significant dierences in survival in whole human blood with respect to their parental strain, indicating that hydroxylation in the lipid A secondary chains did not contribute to blood resistance in P. aeruginosa.",A Lo Sciuto 2019,2019,2 genes,Lo Sciuto-2019-Genetic Basis and Physiological,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15557,PHI:9931,UniProt,A0A069PXM6,GenBank,CEI16009,,,MH19,lpxO1,,,,,,PHI:9932,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,blood,aspartyl/asparaginyl beta-hydroxylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,sodium dodecyl sulphate (SDS); colistin; novobiocin; ciprofloxacin; imipenem; rifampicin; streptomycin; tobramycin; erythromycin,sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; novobiocin: CHEBI:28368; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; rifampicin: CHEBI:28077; streptomycin: CHEBI:17076; tobramycin: CHEBI:28864; erythromycin: CHEBI:48923,,,,,gene deletion: full; gene complementation,,,YVS,31835493,PubMed,10.3390/pathogens8040291,Pathogens. 2019 Dec 10;8(4),francesco.imperi@uniroma3.it,"None of the lpxO mutants showed significant dierences in survival in whole human blood with respect to their parental strain, indicating that hydroxylation in the lipid A secondary chains did not contribute to blood resistance in P. aeruginosa.",A Lo Sciuto 2019,2019,2 genes,Lo Sciuto-2019-Genetic Basis and Physiological,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15558,PHI:9932,UniProt,Q9I522,GenBank,AE004528_3,,,PAO1,lpxO2,,,,,,PHI:9931,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,blood,lipopolysaccharide biosynthetic protein LpxO2,,,,unaffected pathogenicity,,,,,,,,wild type,,no,sodium dodecyl sulphate (SDS); colistin; novobiocin; ciprofloxacin; imipenem; rifampicin; streptomycin; tobramycin; erythromycin,sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; novobiocin: CHEBI:28368; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; rifampicin: CHEBI:28077; streptomycin: CHEBI:17076; tobramycin: CHEBI:28864; erythromycin: CHEBI:48923,,,,,gene deletion: full; gene complementation,,,YVS,31835493,PubMed,10.3390/pathogens8040291,Pathogens. 2019 Dec 10;8(4),francesco.imperi@uniroma3.it,"None of the lpxO mutants showed significant dierences in survival in whole human blood with respect to their parental strain, indicating that hydroxylation in the lipid A secondary chains did not contribute to blood resistance in P. aeruginosa.",A Lo Sciuto 2019,2019,2 genes,Lo Sciuto-2019-Genetic Basis and Physiological,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15559,PHI:9931,UniProt,A0A069PXM6,GenBank,CEI16009,,,MH19,lpxO1,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,aspartyl/asparaginyl beta-hydroxylase,,,,reduced virulence,,,,,,,,wild type,,no,sodium dodecyl sulphate (SDS); colistin; novobiocin; ciprofloxacin; imipenem; rifampicin; streptomycin; tobramycin; erythromycin,sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; novobiocin: CHEBI:28368; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; rifampicin: CHEBI:28077; streptomycin: CHEBI:17076; tobramycin: CHEBI:28864; erythromycin: CHEBI:48923,,,,,gene deletion: full; gene complementation,,,YVS,31835493,PubMed,10.3390/pathogens8040291,Pathogens. 2019 Dec 10;8(4),francesco.imperi@uniroma3.it,"A four-and almost eight-fold increase in the LD90 of the ΔlpxO2 and ΔlpxO1ΔlpxO2 mutants was observed with respect to the wild type, respectively.",A Lo Sciuto 2019,2019,2 genes,Lo Sciuto-2019-Genetic Basis and Physiological,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15560,PHI:9932,UniProt,Q9I522,GenBank,AE004528_3,,,PAO1,lpxO2,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,lipopolysaccharide biosynthetic protein LpxO2,,,,reduced virulence,,,,,,,,wild type,,no,sodium dodecyl sulphate (SDS); colistin; novobiocin; ciprofloxacin; imipenem; rifampicin; streptomycin; tobramycin; erythromycin,sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; novobiocin: CHEBI:28368; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; rifampicin: CHEBI:28077; streptomycin: CHEBI:17076; tobramycin: CHEBI:28864; erythromycin: CHEBI:48923,,,,,gene deletion: full; gene complementation,,,YVS,31835493,PubMed,10.3390/pathogens8040291,Pathogens. 2019 Dec 10;8(4),francesco.imperi@uniroma3.it,"A four-and almost eight-fold increase in the LD90 of the ΔlpxO2 and ΔlpxO1ΔlpxO2 mutants was observed with respect to the wild type, respectively.",A Lo Sciuto 2019,2019,2 genes,Lo Sciuto-2019-Genetic Basis and Physiological,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15561,PHI:9931,UniProt,A0A069PXM6,GenBank,CEI16009,,,MH19,lpxO1,,,,,,PHI:9932,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,aspartyl/asparaginyl beta-hydroxylase,,,,reduced virulence,,,,,,,,wild type,,no,sodium dodecyl sulphate (SDS); colistin; novobiocin; ciprofloxacin; imipenem; rifampicin; streptomycin; tobramycin; erythromycin,sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; novobiocin: CHEBI:28368; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; rifampicin: CHEBI:28077; streptomycin: CHEBI:17076; tobramycin: CHEBI:28864; erythromycin: CHEBI:48923,,,,,gene deletion: full; gene complementation,,,YVS,31835493,PubMed,10.3390/pathogens8040291,Pathogens. 2019 Dec 10;8(4),francesco.imperi@uniroma3.it,"A four-and almost eight-fold increase in the LD90 of the ΔlpxO2 and ΔlpxO1ΔlpxO2 mutants was observed with respect to the wild type, respectively.",A Lo Sciuto 2019,2019,2 genes,Lo Sciuto-2019-Genetic Basis and Physiological,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15562,PHI:9932,UniProt,Q9I522,GenBank,AE004528_3,,,PAO1,lpxO2,,,,,,PHI:9931,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,lipopolysaccharide biosynthetic protein LpxO2,,,,reduced virulence,,,,,,,,wild type,,no,sodium dodecyl sulphate (SDS); colistin; novobiocin; ciprofloxacin; imipenem; rifampicin; streptomycin; tobramycin; erythromycin,sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; novobiocin: CHEBI:28368; ciprofloxacin: CHEBI:100241; imipenem: CHEBI:471744; rifampicin: CHEBI:28077; streptomycin: CHEBI:17076; tobramycin: CHEBI:28864; erythromycin: CHEBI:48923,,,,,gene deletion: full; gene complementation,,,YVS,31835493,PubMed,10.3390/pathogens8040291,Pathogens. 2019 Dec 10;8(4),francesco.imperi@uniroma3.it,"A four-and almost eight-fold increase in the LD90 of the ΔlpxO2 and ΔlpxO1ΔlpxO2 mutants was observed with respect to the wild type, respectively.",A Lo Sciuto 2019,2019,2 genes,Lo Sciuto-2019-Genetic Basis and Physiological,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15563,PHI:9933,UniProt,A0A5A4WCC8,GenBank,BBN48638,,,JP-H-1,lysX,,,,,,,1764,Mycobacterium avium,243243,subsp. hominissuis strain 104,lung disease; subacute cervical lymphadenitis; chronic cervical lymphadenitis,primates,9606,Homo sapiens (related: human),hMDMs,,,macrophage,lysylphosphatidylglycerol biosynthesis bifunctional protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,hydrogen peroxide (H2O2); diethylenetriamine/nitric oxide adduct,hydrogen peroxide (H2O2): CHEBI:16240; diethylenetriamine/nitric oxide adduct CAS no.: CAS:146724-94-9,,,,,gene deletion: full; gene complementation,,,YVS,31996090,PubMed,10.1080/21505594.2020.1713690,Virulence. 2020 Dec;11(1):132-144,Lewina@rki.de,The lysX mutant exhibited increased inflammatory response in PBMC and multi-nucleated giant cell (MGC) formation in human macrophages during infection studies.Monocyte-derived macrophages,G Kirubakar 2020,2020,1 gene,Kirubakar-2020-Mutation on lysX from Mycobacte,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15564,PHI:9933,UniProt,A0A5A4WCC8,GenBank,BBN48638,,,JP-H-1,lysX,,,,,,,1764,Mycobacterium avium,243243,subsp. hominissuis strain 104,lung disease; subacute cervical lymphadenitis; chronic cervical lymphadenitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,lysylphosphatidylglycerol biosynthesis bifunctional protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,hydrogen peroxide (H2O2); diethylenetriamine/nitric oxide adduct,hydrogen peroxide (H2O2): CHEBI:16240; diethylenetriamine/nitric oxide adduct CAS no.: CAS:146724-94-9,,,,,gene deletion: full; gene complementation,,,YVS,31996090,PubMed,10.1080/21505594.2020.1713690,Virulence. 2020 Dec;11(1):132-144,Lewina@rki.de,The lysX mutant strain revealed to be more reproductive in the Galleria mellonella infection model.,G Kirubakar 2020,2020,1 gene,Kirubakar-2020-Mutation on lysX from Mycobacte,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15565,PHI:9934,UniProt,A0A133Q5J9,GenBank,KXA38142,,,MJR7738,lytS,,,,,,PHI:9935,28035,Staphylococcus lugdunensis,,DSM 4804,infective endocarditis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,sensor protein,,,,reduced virulence,,,,,,,,,,no,triton X-100,Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,32038604,PubMed,10.3389/fmicb.2020.00039,Front Microbiol. 2020 Jan 24;11:39,sandrine.dahyot@chu-rouen.fr,Deletion of lytSR was found to hamper biofilm formation.,S Dahyot 2020,2020,2 genes,Dahyot-2020-Role of the LytSR Two-Component Re,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15566,PHI:9935,UniProt,A0A133QAP1,GenBank,KXA39972,,,MJR7738,lytR,,,,,,PHI:9934,28035,Staphylococcus lugdunensis,,DSM 4804,infective endocarditis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,putative transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,triton X-100,Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,32038604,PubMed,10.3389/fmicb.2020.00039,Front Microbiol. 2020 Jan 24;11:39,sandrine.dahyot@chu-rouen.fr,Deletion of lytSR was found to hamper biofilm formation.,S Dahyot 2020,2020,2 genes,Dahyot-2020-Role of the LytSR Two-Component Re,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15567,PHI:9934,UniProt,A0A133Q5J9,GenBank,KXA38142,,,MJR7738,lytS,,,,,,PHI:9935,28035,Staphylococcus lugdunensis,,DSM 4804,infective endocarditis,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,sensor protein,,,,unaffected pathogenicity,,,,,,,,,,no,triton X-100,Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,32038604,PubMed,10.3389/fmicb.2020.00039,Front Microbiol. 2020 Jan 24;11:39,sandrine.dahyot@chu-rouen.fr,Deletion of lytSR was found to hamper biofilm formation.,S Dahyot 2020,2020,2 genes,Dahyot-2020-Role of the LytSR Two-Component Re,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15568,PHI:9935,UniProt,A0A133QAP1,GenBank,KXA39972,,,MJR7738,lytR,,,,,,PHI:9934,28035,Staphylococcus lugdunensis,,DSM 4804,infective endocarditis,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,putative transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,triton X-100,Triton X-100: CHEBI:9750,,,,,gene deletion: full; gene complementation,,,YVS,32038604,PubMed,10.3389/fmicb.2020.00039,Front Microbiol. 2020 Jan 24;11:39,sandrine.dahyot@chu-rouen.fr,Deletion of lytSR was found to hamper biofilm formation.,S Dahyot 2020,2020,2 genes,Dahyot-2020-Role of the LytSR Two-Component Re,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15569,PHI:9936,UniProt,no data found,GenBank,,,,,M949_RS00050,,,,,,,34085,Riemerella anatipestifer,1354240,serotype 1 strain CH3,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,serum,putative protein containing an outer membrane protein beta-barrel domain,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31902494,PubMed,10.1016/j.vetmic.2019.108548,Vet Microbiol. 2020 Jan;240:108548,yus@shvri.ac.cn,"Bacterial adherence and invasion abilities, bacterial capsular polysaccharide quantity, biofilm formation capacity and the bacterial virulence of the mutant strain were decreased, compared to the wild-type strain CH3.",T Li 2020,2020,1 gene,Li-2020-Characterization of the Riemerella ana,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15570,PHI:9936,UniProt,no data found,GenBank,,,,,M949_RS00050,,,,,,,34085,Riemerella anatipestifer,1354240,serotype 1 strain CH3,septicemia,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,putative protein containing an outer membrane protein beta-barrel domain,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,31902494,PubMed,10.1016/j.vetmic.2019.108548,Vet Microbiol. 2020 Jan;240:108548,yus@shvri.ac.cn,The capacity for the invasion of CH3ΔM949_RS00050 to Vero cells was decreased.Kidney epithelial cells,T Li 2020,2020,1 gene,Li-2020-Characterization of the Riemerella ana,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15571,PHI:9937,UniProt,A0A1D8PJZ6,GenBank,AOW28447,,,SC5314,snf5,chromosome 3,,,,,,5476,Candida albicans,,SN250,candidiasis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,stomach; cecum; colon,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,Congo red,Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,YVS,31809527,PubMed,10.1371/journal.ppat.1007823,PLoS Pathog. 2019 Dec 6;15(12):e1007823,adnane.sellam.1@ulaval.ca,"Snf5 mutant was unable to maintain its growth in stomach, cecum and colon of mice.",A Burgain 2019,2019,1 gene,Burgain-2019-A novel genetic circuitry governi,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15572,PHI:9937,UniProt,A0A1D8PJZ6,GenBank,AOW28447,,,SC5314,snf5,chromosome 3,,,,,,5476,Candida albicans,,SN250,candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,Congo red,Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,YVS,31809527,PubMed,10.1371/journal.ppat.1007823,PLoS Pathog. 2019 Dec 6;15(12):e1007823,adnane.sellam.1@ulaval.ca,Snf5 mutant was also avirulent as it was unable to invade Galleria larvae or to cause damage to human enterocytes and murine macrophages.,A Burgain 2019,2019,1 gene,Burgain-2019-A novel genetic circuitry governi,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15573,PHI:9937,UniProt,A0A1D8PJZ6,GenBank,AOW28447,,,SC5314,snf5,chromosome 3,,,,,,5476,Candida albicans,,SN250,candidiasis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colon epithelial cell,transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,Congo red,Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,YVS,31809527,PubMed,10.1371/journal.ppat.1007823,PLoS Pathog. 2019 Dec 6;15(12):e1007823,adnane.sellam.1@ulaval.ca,Snf5 mutant was also avirulent as it was unable to invade Galleria larvae or to cause damage to human enterocytes and murine macrophages.,A Burgain 2019,2019,1 gene,Burgain-2019-A novel genetic circuitry governi,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15574,PHI:9937,UniProt,A0A1D8PJZ6,GenBank,AOW28447,,,SC5314,snf5,chromosome 3,,,,,,5476,Candida albicans,,SN250,candidiasis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,Congo red,Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,YVS,31809527,PubMed,10.1371/journal.ppat.1007823,PLoS Pathog. 2019 Dec 6;15(12):e1007823,adnane.sellam.1@ulaval.ca,Snf5 mutant was also avirulent as it was unable to invade Galleria larvae or to cause damage to human enterocytes and murine macrophages.,A Burgain 2019,2019,1 gene,Burgain-2019-A novel genetic circuitry governi,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15575,PHI:9938,UniProt,A0A0P9VJL6,GenBank,AOR51355,,,Psn23,matE,,,,,,,29438,Pseudomonas savastanoi,360921,pv. nerii strain Psn23,plant disease,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Burley White,,,leaf,toxic compound extrusion transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31979049,PubMed,10.3390/microorganisms8020156,Microorganisms. 2020 Jan 22;8(2),stefania.tegli@unifi.it,A hypovirulent phenotype was scored for the Psn23 mutants having their MATE transporter somehow impaired and also showed a reduced in vitro IAA production in comparison with the wild-type Psn23.,S Tegli 2020,2020,1 gene,Tegli-2020-A MATE Transporter is Involved in P,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15576,PHI:9938,UniProt,A0A0P9VJL6,GenBank,AOR51355,,,Psn23,matE,,"D182A, Y200A and T17035A",,,,,29438,Pseudomonas savastanoi,360921,pv. nerii strain Psn23,plant disease,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Burley White,,,leaf,toxic compound extrusion transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,YVS,31979049,PubMed,10.3390/microorganisms8020156,Microorganisms. 2020 Jan 22;8(2),stefania.tegli@unifi.it,A hypovirulent phenotype was scored for the Psn23 mutants having their MATE transporter somehow impaired and also showed a reduced in vitro IAA production in comparison with the wild-type Psn23.,S Tegli 2020,2020,1 gene,Tegli-2020-A MATE Transporter is Involved in P,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15577,PHI:9939,UniProt,B8NSQ3,GenBank,EED46951,,,NRRL3357,dnjA (AFLA_050040 ),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,infection,monocots,4577,Zea mays (related: maize),,,,kernel,J domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32060628,PubMed,10.1007/s00294-020-01058-y,Curr Genet. 2020 Feb 14,phsoo97@knu.ac.kr,"The deletion of dnjA decreased the number of asexual spores (conidia), produced abnormal conidiophores, and reduced sexual fruiting bodies (cleistothecia) or sclerotia.",Y E Son 2020,2020,1 gene,Son-2020-The role of the VosA-repressed dnjA g,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15578,PHI:9940,UniProt,Q0P9D3,GenBank,CAL35238,,,NCTC 11168,pglE,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,gastroenteritis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line,,,intestinal epithelial cell,UDP-N-acetylbacillosamine transaminase,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,YVS,31965157,PubMed,10.1093/glycob/cwz105,Glycobiology. 2020 Jan 15,imper@mit.edu,The glycosylation-impaired strain 11168 ΔpglE was 100-fold less capable of adhering to and invading this intestinal model in cell infectivity assays.,C Y Zamora 2020,2020,1 gene,Zamora-2020-Application of a gut-immune co-cul,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15579,PHI:9940,UniProt,Q0P9D3,GenBank,CAL35238,,,NCTC 11168,pglE,,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,gastroenteritis,primates,9606,Homo sapiens (related: human),HT-29-MTX cell line,,,intestinal epithelial cell,UDP-N-acetylbacillosamine transaminase,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,YVS,31965157,PubMed,10.1093/glycob/cwz105,Glycobiology. 2020 Jan 15,imper@mit.edu,The glycosylation-impaired strain 11168 ΔpglE was 100-fold less capable of adhering to and invading this intestinal model in cell infectivity assays.,C Y Zamora 2020,2020,1 gene,Zamora-2020-Application of a gut-immune co-cul,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15580,PHI:9941,UniProt,S7UWV2,GenBank,EPR62185,,,GT1,SABP1 (TGGT1_225940),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,dendritic cell,sialic acid-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32060530,PubMed,10.1093/infdis/jiaa072,J Infect Dis. 2020 Feb 15,qijunchen759@syau.edu.cn,Parasites with TgSABP1 gene deletion lost their invasion capability.,M Xing 2020,2020,1 gene,Xing-2020-A sialic acid-binding protein SABP1,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15581,PHI:9941,UniProt,S7UWV2,GenBank,EPR62185,,,GT1,SABP1 (TGGT1_225940),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,sialic acid-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32060530,PubMed,10.1093/infdis/jiaa072,J Infect Dis. 2020 Feb 15,qijunchen759@syau.edu.cn,Parasites with TgSABP1 gene deletion lost their invasion capability. Kidney epithelial cells,M Xing 2020,2020,1 gene,Xing-2020-A sialic acid-binding protein SABP1,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15582,PHI:9943,UniProt,A0A507D1H9,GenBank,QDG08162,,,MB42,avrSen1 (SeMB42_g04087),,,,,,,286115,Synchytrium endobioticum,,pathotype 1(D1) isolate MB42,potato wart,eudicots,4113,Solanum tuberosum (related: potato),cv. Erika,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31246152,PubMed,10.1094/MPMI-05-19-0138-R,Mol Plant Microbe Interact. 2019 Nov;32(11):1536-1546,jack.vossen@wur.nl,"Expression of this candidate in potato Sen1 plants showed a specific hypersensitive response (HR), which cosegregated with the Sen1 resistance in potato populations. No HR was obtained with truncated genes found in pathotypes that evaded recognition by Sen1.",B T L H van de Vossenberg 2019,2019,1 gene,van de Vossenbe-2019-The Synchytrium endobioti,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15583,PHI:9944,UniProt,A0A2U8ZT94,GenBank,AWO14273,,,Z7,Ste12,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),,,,leaf,transcription factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31824437,PubMed,10.3389/fmicb.2019.02514,Front Microbiol. 2019 Nov 22;10:2514,hyli@zju.edu.cn,Pathogenicity tests assayed on detached Dancy leaves revealed a marked reduction in virulence of ΔSte12.,H Ma 2019,2019,3 genes,Ma-2019-Cell-Wall-Degrading Enzymes Required f,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15584,PHI:9945,UniProt,no data found,GenBank,OWY42162,,,Z7,AaCut3 (AALT_g1915),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),,,,leaf,cutinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31824437,PubMed,10.3389/fmicb.2019.02514,Front Microbiol. 2019 Nov 22;10:2514,hyli@zju.edu.cn,The AaCut3 or AaCut7 deficient strain unchanged in cutinase activities and incited wild-type lesions on Dancy leaves.,H Ma 2019,2019,3 genes,Ma-2019-Cell-Wall-Degrading Enzymes Required f,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15585,PHI:9946,UniProt,no data found,GenBank,OWY48646,,,Z7,AaCut7 (AALT_g8018),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),,,,leaf,cutinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31824437,PubMed,10.3389/fmicb.2019.02514,Front Microbiol. 2019 Nov 22;10:2514,hyli@zju.edu.cn,The AaCut3 or AaCut7 deficient strain unchanged in cutinase activities and incited wild-type lesions on Dancy leaves.,H Ma 2019,2019,3 genes,Ma-2019-Cell-Wall-Degrading Enzymes Required f,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15586,PHI:9945,UniProt,no data found,GenBank,OWY42162,,,Z7,AaCut3 (AALT_g1915),,,,,,PHI:9946,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),,,,leaf,cutinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31824437,PubMed,10.3389/fmicb.2019.02514,Front Microbiol. 2019 Nov 22;10:2514,hyli@zju.edu.cn,The strain carrying an AaCut3 AaCut7 double mutation produced and secreted significantly fewer cutinases and incited smaller necrotic lesions than wild type.,H Ma 2019,2019,3 genes,Ma-2019-Cell-Wall-Degrading Enzymes Required f,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15587,PHI:9946,UniProt,no data found,GenBank,OWY48646,,,Z7,AaCut7 (AALT_g8018),,,,,,PHI:9945,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),,,,leaf,cutinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31824437,PubMed,10.3389/fmicb.2019.02514,Front Microbiol. 2019 Nov 22;10:2514,hyli@zju.edu.cn,The strain carrying an AaCut3 AaCut7 double mutation produced and secreted significantly fewer cutinases and incited smaller necrotic lesions than wild type.,H Ma 2019,2019,3 genes,Ma-2019-Cell-Wall-Degrading Enzymes Required f,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15588,PHI:9947,UniProt,J9XY03,GenBank,AFS33086,,,FS090425-1,eha,,,,,,,636,Edwardsiella tarda,,ET13,necrotic abscesses,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,hemolysin activator protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31865430,PubMed,10.1007/s00203-019-01794-x,Arch Microbiol. 2019 Dec 21,yzgqzhu@yzu.edu.cn,"Biofilm formation, hemolytic activity and adhesion to Caco-2 cells were decreased in an E. tarda mutant strain with deletion in-frame isogenic gene eha (Δeha). Epithelial colorectal adenocarcinoma cells",H A Hassan 2019,2019,1 gene,Hassan-2019-Fish borne Edwardsiella tarda eha,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15589,PHI:9947,UniProt,J9XY03,GenBank,AFS33086,,,FS090425-1,eha,,,,,,,636,Edwardsiella tarda,,ET13,necrotic abscesses,bony fishes,7955,Danio rerio (related: zebrafish),,,,,hemolysin activator protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31865430,PubMed,10.1007/s00203-019-01794-x,Arch Microbiol. 2019 Dec 21,yzgqzhu@yzu.edu.cn,"Biofilm formation, hemolytic activity and adhesion to Caco-2 cells were decreased in an E. tarda mutant strain with deletion in-frame isogenic gene eha (Δeha).",H A Hassan 2019,2019,1 gene,Hassan-2019-Fish borne Edwardsiella tarda eha,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15590,PHI:9948,UniProt,K9G6R2,GenBank,QIA50577,,,,dcl1,,,,,,,36651,Penicillium digitatum,,,blue mold (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruit; exocarp,dicer-like protein 1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,32033176,PubMed,10.3390/cells9020363,Cells. 2020 Feb 4;9(2),sy6302@sohu.com,"Neither transformant showed a change in mycelial growth or sporulation ability, but the pathogenicity of the Pit-DCL2 RNAi transformant to citrus fruits was severely impaired, compared to that of the Pit-DCL1 RNAi transformant and the wild type.",C Yin 2020,2020,2 genes,Yin-2020-Silencing Dicer-Like Genes Reduces Vi,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15591,PHI:9949,UniProt,no data found,GenBank,QIA50578,,,,dcl2,,,,,,,36651,Penicillium digitatum,,,blue mold (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruit; exocarp,dicer-like protein 2,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,32033176,PubMed,10.3390/cells9020363,Cells. 2020 Feb 4;9(2),sy6302@sohu.com,"Neither transformant showed a change in mycelial growth or sporulation ability, but the pathogenicity of the Pit-DCL2 RNAi transformant to citrus fruits was severely impaired, compared to that of the Pit-DCL1 RNAi transformant and the wild type.",C Yin 2020,2020,2 genes,Yin-2020-Silencing Dicer-Like Genes Reduces Vi,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15592,PHI:9950,UniProt,no data found,GenBank,,,,,LmCBP1,,,,,,,5022,Leptosphaeria maculans,985895,JN3,blackleg,eudicots,3708,Brassica napus (related: rape),cv. Westar; cv. MT29; cv. Glacier; cv. 02-22-2-1; cv. Jet Neuf; cv. Forge; cv. 01-23-2; cv. Goeland; cv. 1135; cv. Surpass400,,,cotyledon,secreted chitin-binding protein,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,YVS,31863838,PubMed,10.1016/j.fgb.2019.103320,Fungal Genet Biol. 2019 Dec 19;136:103320,dilantha.fernando@umanitoba.ca,The mutants were more sensitive to H2O2 compared to wild type.,F Liu 2019,2019,1 gene,"Liu-2019-LmCBP1, a secreted chitin-binding pro",BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15593,PHI:9950,UniProt,no data found,GenBank,,,,,LmCBP1,,,,,,,5022,Leptosphaeria maculans,985895,JN3,blackleg,eudicots,3708,Brassica napus (related: rape),cv. Westar; cv. MT29; cv. Glacier; cv. 02-22-2-1; cv. Jet Neuf; cv. Forge; cv. 01-23-2; cv. Goeland; cv. 1135; cv. Surpass400,,,cotyledon,secreted chitin-binding protein,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,YVS,31863838,PubMed,10.1016/j.fgb.2019.103320,Fungal Genet Biol. 2019 Dec 19;136:103320,dilantha.fernando@umanitoba.ca,The mutants were more sensitive to H2O2 compared to wild type.,F Liu 2019,2019,1 gene,"Liu-2019-LmCBP1, a secreted chitin-binding pro",BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15594,PHI:9951,UniProt,G4MND2,GenBank,EHA57046,,,70-15,MoFap7 (MGG_16212),chromosome 1,,,MoCdc42 (MGG_00466); MoRac1 (MGG_02731); MoMst50 (MGG_05199); MoRps14 (MGG_05238),UniProt: G4NC11; GenBank: EHA49014; UniProt: G5EH19; GenBank: EHA46282; UniProt: G4N525; Gen,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ribosome assembly factor,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31814506,PubMed,10.1080/21505594.2019.1697123,Virulence. 2019 Dec;10(1):1047-1063,fuchenglin@zju.edu.cn,"ΔMofap7 mutants exhibited defects in growth and development, conidial morphology, appressorium formation and infection, and were sensitive to oxidative stress.",L Li 2019,2019,1 gene,"Li-2019-MoFap7, a ribosome assembly factor, is",BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15595,PHI:9951,UniProt,G4MND2,GenBank,EHA57046,,,70-15,MoFap7 (MGG_16212),chromosome 1,,,MoCdc42 (MGG_00466); MoRac1 (MGG_02731); MoMst50 (MGG_05199); MoRps14 (MGG_05238),UniProt: G4NC11; GenBank: EHA49014; UniProt: G5EH19; GenBank: EHA46282; UniProt: G4N525; Gen,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,ribosome assembly factor,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31814506,PubMed,10.1080/21505594.2019.1697123,Virulence. 2019 Dec;10(1):1047-1063,fuchenglin@zju.edu.cn,"ΔMofap7 mutants exhibited defects in growth and development, conidial morphology, appressorium formation and infection, and were sensitive to oxidative stress.",L Li 2019,2019,1 gene,"Li-2019-MoFap7, a ribosome assembly factor, is",BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15596,PHI:9952,UniProt,G4N3H1,GenBank,EHA52646,,,70-15,Ubp4 (MGG_04957),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,seedling,putative ubiquitin carboxyl-terminal hydrolase,,,,loss of pathogenicity,,yes,yes,yes,,reduced,wild type,reduced,reduced,no,SDS; Congo red,SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31872271,PubMed,10.1007/s00294-019-01049-8,Curr Genet. 2019 Dec 23,zhywang@zju.edu.cn,"Targeted gene deletion mutants of MoUBP4 are signifcantly reduced in mycelial growth, conidiation, and increased in tolerance to SDS and CR (Congo red) cell-wall damage.",Y Que 2019,2019,1 gene,Que-2019-The putative deubiquitinating enzyme,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15597,PHI:9952,UniProt,G4N3H1,GenBank,EHA52646,,,70-15,Ubp4 (MGG_04957),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,putative ubiquitin carboxyl-terminal hydrolase,,,,loss of pathogenicity,,yes,yes,yes,,reduced,wild type,reduced,reduced,no,SDS; Congo red,SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,31872271,PubMed,10.1007/s00294-019-01049-8,Curr Genet. 2019 Dec 23,zhywang@zju.edu.cn,"Targeted gene deletion mutants of MoUBP4 are signifcantly reduced in mycelial growth, conidiation, and increased in tolerance to SDS and CR (Congo red) cell-wall damage.",Y Que 2019,2019,1 gene,Que-2019-The putative deubiquitinating enzyme,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15598,PHI:9953,UniProt,no data found,GenBank,EKJ70677,,,CS3096,PKS6,,,,,,PHI:9954,101028,Fusarium pseudograminearum,,CS11286,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Mace,,,seedling,polyketide synthase,,,fusaristatin A production,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full,,,YVS,31809785,PubMed,10.1016/j.fgb.2019.103314,Fungal Genet Biol. 2019 Dec 4;136:103314,Khudhair@csiro.au,Fusaristatin A had a negative effect on fungal development and aggressiveness.,M Khudhair 2019,2019,2 genes,Khudhair-2019-Fusaristatin A production negati,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15599,PHI:9954,UniProt,no data found,GenBank,,,,,NRPS7,,,,,,PHI:9953,101028,Fusarium pseudograminearum,,CS11286,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Mace,,,seedling,non-ribosomal peptide synthetase,,,fusaristatin A production,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full,,,YVS,31809785,PubMed,10.1016/j.fgb.2019.103314,Fungal Genet Biol. 2019 Dec 4;136:103314,Khudhair@csiro.au,Fusaristatin A had a negative effect on fungal development and aggressiveness.,M Khudhair 2019,2019,2 genes,Khudhair-2019-Fusaristatin A production negati,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15600,PHI:9953,UniProt,no data found,GenBank,EKJ70677,,,CS3096,PKS6,,,,,,PHI:9954,101028,Fusarium pseudograminearum,,CS5519,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Mace,,,seedling,polyketide synthase,,,fusaristatin A production,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full,,,YVS,31809785,PubMed,10.1016/j.fgb.2019.103314,Fungal Genet Biol. 2019 Dec 4;136:103314,Khudhair@csiro.au,Fusaristatin A had a negative effect on fungal development and aggressiveness.,M Khudhair 2019,2019,2 genes,Khudhair-2019-Fusaristatin A production negati,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15601,PHI:9954,UniProt,no data found,GenBank,,,,,NRPS7,,,,,,PHI:9953,101028,Fusarium pseudograminearum,,CS5519,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Mace,,,seedling,non-ribosomal peptide synthetase,,,fusaristatin A production,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full,,,YVS,31809785,PubMed,10.1016/j.fgb.2019.103314,Fungal Genet Biol. 2019 Dec 4;136:103314,Khudhair@csiro.au,Fusaristatin A had a negative effect on fungal development and aggressiveness.,M Khudhair 2019,2019,2 genes,Khudhair-2019-Fusaristatin A production negati,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15602,PHI:9955,UniProt,P10069,GenBank,AAA33300,,,,brlA,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,C2H2 type master regulator of conidiophore development,,,conidiation pathway,reduced virulence,,,,,,,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32019801,PubMed,10.1128/mBio.03202-19,mBio. 2020 Feb 4;11(1),don.sheppard@mcgill.ca,Overexpression of brlA attenuated A. fumigatus virulence in both an invertebrate and mouse model of invasive aspergillosis.,J I P Stewart 2020,2020,1 gene,Stewart-2020-Reducing Aspergillus fumigatus Vi,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15603,PHI:9955,UniProt,P10069,GenBank,AAA33300,,,,brlA,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,C2H2 type master regulator of conidiophore development,,,conidiation pathway,reduced virulence,,,,,,,,reduced,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32019801,PubMed,10.1128/mBio.03202-19,mBio. 2020 Feb 4;11(1),don.sheppard@mcgill.ca,Overexpression of brlA attenuated A. fumigatus virulence in both an invertebrate and mouse model of invasive aspergillosis.,J I P Stewart 2020,2020,1 gene,Stewart-2020-Reducing Aspergillus fumigatus Vi,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15604,PHI:9956,UniProt,G4NEN3,GenBank,EHA48663,,,70-15,RBP9 (MGG_00753),chromosome 5,,,,,,318829,Magnaporthe oryzae,,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,seedling; leaf sheath; leaf,Ran-binding protein microtubule-organizing center,,,,reduced virulence,,yes,,,,reduced,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31832037,PubMed,10.5423/PPJ.OA.07.2019.0204,Plant Pathol J. 2019 Dec;35(6):564-574,kims@kangwon.ac.kr,"ΔMorbp9 still developed aberrantly shaped appressorium-like structures at hyphal tips on the same surface, suggesting that MoRBP9 is involved in the morphology of appressorium-like structures from hyphal tips and is critical for development of appressorium from germ tubes.",T Fu 2019,2019,1 gene,Fu-2019-MoRBP9 Encoding a Ran-Binding Protein,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15605,PHI:9961,UniProt,J9VHN6,GenBank,AFR93917,,,H99,bim1 (CNAG_02775),chromosome 3,,,,,PHI:9962,5207,Cryptococcus neoformans,235443,H99,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),A/J,,,,uncharacterized protein,,,copper uptake pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31932719,PubMed,10.1038/s41589-019-0437-9,Nat Chem Biol. 2020 Mar;16(3):337-344,dennis.thiele@duke.edu,Bim1 participated in Cu uptake in concert with Ctr1 and expression of this pathway drives brain colonization in mouse infection models.,S Garcia-Santamarina 2020,2020,2 genes,Garcia-Santamar-2020-A lytic polysaccharide mo,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15606,PHI:9962,UniProt,J9VLN4,GenBank,AFR95168,,,H99,ctr4,chromosome 5,,,,,PHI:9961,5207,Cryptococcus neoformans,235443,H99,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),A/J,,,,copper transport protein,,,copper uptake pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31932719,PubMed,10.1038/s41589-019-0437-9,Nat Chem Biol. 2020 Mar;16(3):337-344,dennis.thiele@duke.edu,Bim1 participated in Cu uptake in concert with Ctr1 and expression of this pathway drives brain colonization in mouse infection models.,S Garcia-Santamarina 2020,2020,2 genes,Garcia-Santamar-2020-A lytic polysaccharide mo,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15607,PHI:9961,UniProt,J9VHN6,GenBank,AFR93917,,,H99,bim1 (CNAG_02775),chromosome 3,,,,,PHI:9962,5207,Cryptococcus neoformans,235443,H99,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,uncharacterized protein,,,copper uptake pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31932719,PubMed,10.1038/s41589-019-0437-9,Nat Chem Biol. 2020 Mar;16(3):337-344,dennis.thiele@duke.edu,Bim1 participated in Cu uptake in concert with Ctr1 and expression of this pathway drives brain colonization in mouse infection models.,S Garcia-Santamarina 2020,2020,2 genes,Garcia-Santamar-2020-A lytic polysaccharide mo,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15608,PHI:9962,UniProt,J9VLN4,GenBank,AFR95168,,,H99,ctr4,chromosome 5,,,,,PHI:9961,5207,Cryptococcus neoformans,235443,H99,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,copper transport protein,,,copper uptake pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31932719,PubMed,10.1038/s41589-019-0437-9,Nat Chem Biol. 2020 Mar;16(3):337-344,dennis.thiele@duke.edu,Bim1 participated in Cu uptake in concert with Ctr1 and expression of this pathway drives brain colonization in mouse infection models.,S Garcia-Santamarina 2020,2020,2 genes,Garcia-Santamar-2020-A lytic polysaccharide mo,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15609,PHI:9962,UniProt,J9VLN4,GenBank,AFR95168,,,H99,ctr4,chromosome 5,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,copper transport protein,,,copper uptake pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31932719,PubMed,10.1038/s41589-019-0437-9,Nat Chem Biol. 2020 Mar;16(3):337-344,dennis.thiele@duke.edu,Bim1 participated in Cu uptake in concert with Ctr1 and expression of this pathway drives brain colonization in mouse infection models.,S Garcia-Santamarina 2020,2020,2 genes,Garcia-Santamar-2020-A lytic polysaccharide mo,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15610,PHI:9963,UniProt,Q88AM7,GenBank,AAO53906,,,DC3000,setA (PSPTO_0362),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,chlorosis,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,"transcriptional regulator, DeoR family",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31829102,PubMed,10.1094/MPMI-10-19-0290-R,Mol Plant Microbe Interact. 2020 Mar;33(3):509-518,anderje2@oregonstate.edu,A setA::Tn5 mutant had decreased T3SS deployment during infection and was compromised in its ability to grow in planta and cause disease.,S E Turner 2020,2020,1 gene,Turner-2020-A DeoR-Type Transcription Regulato,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15611,PHI:9964,UniProt,D0ZHS9,GenBank,ACY86472,,,14028S,spvB,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain ATCC 14028s (ΔsipB),typhoid fever-like disease; septicemia; bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,dendritic cell,mono(ADP-ribosyl)transferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31815949,PubMed,10.1371/journal.pone.0226126,PLoS One. 2019 Dec 9;14(12):e0226126,micah.worley@louisville.edu,"SrfH and spvB had a negligible effect, ΔspvC however displayed a 4.2-fold defect at triggering reverse transmigration.",A Gopinath 2019,2019,3 genes,Gopinath-2019-The Salmonella type III effector,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15612,PHI:9965,UniProt,Q8ZQ79,GenBank,AAF73990,,,14028s,srfH,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain ATCC 14028s (ΔsipB),typhoid fever-like disease; septicemia; bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,dendritic cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31815949,PubMed,10.1371/journal.pone.0226126,PLoS One. 2019 Dec 9;14(12):e0226126,micah.worley@louisville.edu,"SrfH and spvB had a negligible effect, ΔspvC however displayed a 4.2-fold defect at triggering reverse transmigration.",A Gopinath 2019,2019,3 genes,Gopinath-2019-The Salmonella type III effector,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15613,PHI:9966,UniProt,P0A2M9,GenBank,AAA27162,,,14028s,spvC,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain ATCC 14028s (ΔsipB),typhoid fever-like disease; septicemia; bacteremia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,dendritic cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31815949,PubMed,10.1371/journal.pone.0226126,PLoS One. 2019 Dec 9;14(12):e0226126,micah.worley@louisville.edu,"SrfH and spvB had a negligible effect, ΔspvC however displayed a 4.2-fold defect at triggering reverse transmigration.",A Gopinath 2019,2019,3 genes,Gopinath-2019-The Salmonella type III effector,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15614,PHI:9967,UniProt,A0A638ILJ8,GenBank,AHS41752,,,EC20120051,cas3 (AV79_16420),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain SE211,food poisoning,rodents,10090,Mus musculus (related: house mouse),MH-S cell line,,,macrophage,CRISPR-associated helicase/endonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31936769,PubMed,10.3390/pathogens9010053,Pathogens. 2020 Jan 10;9(1),cuiluqing@webmail.hzau.edu.cn,Salmonella Δcas3 strain exhibited lower invasion to cell lines.,L Cui 2020,2020,1 gene,Cui-2020-CRISPR-cas3 of Salmonella Upregulates,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15615,PHI:9967,UniProt,A0A638ILJ8,GenBank,AHS41752,,,EC20120051,cas3 (AV79_16420),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain SE211,food poisoning,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,CRISPR-associated helicase/endonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31936769,PubMed,10.3390/pathogens9010053,Pathogens. 2020 Jan 10;9(1),cuiluqing@webmail.hzau.edu.cn,Salmonella Δcas3 strain exhibited lower invasion to cell lines.,L Cui 2020,2020,1 gene,Cui-2020-CRISPR-cas3 of Salmonella Upregulates,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15616,PHI:9967,UniProt,A0A638ILJ8,GenBank,AHS41752,,,EC20120051,cas3 (AV79_16420),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain SE211,food poisoning,primates,9606,Homo sapiens (related: human),SW480 cell line,,,colonic cancer cell line,CRISPR-associated helicase/endonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31936769,PubMed,10.3390/pathogens9010053,Pathogens. 2020 Jan 10;9(1),cuiluqing@webmail.hzau.edu.cn,Salmonella Δcas3 strain exhibited lower invasion to cell lines.,L Cui 2020,2020,1 gene,Cui-2020-CRISPR-cas3 of Salmonella Upregulates,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15617,PHI:9967,UniProt,A0A638ILJ8,GenBank,AHS41752,,,EC20120051,cas3 (AV79_16420),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain SE211,food poisoning,primates,9606,Homo sapiens (related: human),SW620 cell line,,,colonic cancer cell line,CRISPR-associated helicase/endonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31936769,PubMed,10.3390/pathogens9010053,Pathogens. 2020 Jan 10;9(1),cuiluqing@webmail.hzau.edu.cn,Salmonella Δcas3 strain exhibited lower invasion to cell lines.,L Cui 2020,2020,1 gene,Cui-2020-CRISPR-cas3 of Salmonella Upregulates,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15618,PHI:9967,UniProt,A0A638ILJ8,GenBank,AHS41752,,,EC20120051,cas3 (AV79_16420),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain SE211,food poisoning,even-toed ungulates,9823,Sus scrofa (related: pig),IPEC-J2 cell line,,,intestinal epithelial cell,CRISPR-associated helicase/endonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31936769,PubMed,10.3390/pathogens9010053,Pathogens. 2020 Jan 10;9(1),cuiluqing@webmail.hzau.edu.cn,Salmonella Δcas3 strain exhibited lower invasion to cell lines.,L Cui 2020,2020,1 gene,Cui-2020-CRISPR-cas3 of Salmonella Upregulates,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15619,PHI:9967,UniProt,A0A638ILJ8,GenBank,AHS41752,,,EC20120051,cas3 (AV79_16420),,,,,,,28901,Salmonella enterica,149539,subsp. enterica serovar Enteritidis strain SE211,food poisoning,birds,9031,Gallus gallus (related: chicken),,,,blood; liver; spleen; cecum,CRISPR-associated helicase/endonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31936769,PubMed,10.3390/pathogens9010053,Pathogens. 2020 Jan 10;9(1),cuiluqing@webmail.hzau.edu.cn,Biofilm-forming ability of cas3 deleted strain was reduced.,L Cui 2020,2020,1 gene,Cui-2020-CRISPR-cas3 of Salmonella Upregulates,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15620,PHI:9968,UniProt,Q81LW0,GenBank,QEF18766,,,09,sodA1,,,,,,,1396,Bacillus cereus,,0-9,,moths,29058,Helicoverpa armigera (related: cotton bollworm),,,,,superoxide dismutase,,,,reduced virulence,,,,,,reduced,,,,no,paraquat; menadione (vitamin K3),paraquat: CHEBI:34905; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,31897767,PubMed,10.1007/s11274-019-2786-7,World J Microbiol Biotechnol. 2020 Jan 2;36(1):12,gwangbio@henu.edu.cn,"Mutant lacking all four sod genesc aused a reduced death rate of H. armigera of 46.70%, which was slightly higher than that caused by the ΔsodS and ΔsodC strains.",J Zhang 2020,2020,4 genes,Zhang-2020-Four superoxide dismutases of Bacil,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15621,PHI:9969,UniProt,Q814I6,GenBank,QEF19841,,,09,sodA2,,,,,,,1396,Bacillus cereus,,0-9,,moths,29058,Helicoverpa armigera (related: cotton bollworm),,,,,superoxide dismutase,,,,reduced virulence,,,,,,reduced,,,,no,paraquat; menadione (vitamin K3),paraquat: CHEBI:34905; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,31897767,PubMed,10.1007/s11274-019-2786-7,World J Microbiol Biotechnol. 2020 Jan 2;36(1):12,gwangbio@henu.edu.cn,"Mutant lacking all four sod genesc aused a reduced death rate of H. armigera of 46.70%, which was slightly higher than that caused by the ΔsodS and ΔsodC strains.",J Zhang 2020,2020,4 genes,Zhang-2020-Four superoxide dismutases of Bacil,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15622,PHI:9970,UniProt,no data found,GenBank,QEF16174,,,09,sodS,,,,,,,1396,Bacillus cereus,,0-9,,moths,29058,Helicoverpa armigera (related: cotton bollworm),,,,,superoxide dismutase,,,,reduced virulence,,,,,,increased,,,,no,paraquat; menadione (vitamin K3),paraquat: CHEBI:34905; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,31897767,PubMed,10.1007/s11274-019-2786-7,World J Microbiol Biotechnol. 2020 Jan 2;36(1):12,gwangbio@henu.edu.cn,"Mutant lacking all four sod genesc aused a reduced death rate of H. armigera of 46.70%, which was slightly higher than that caused by the ΔsodS and ΔsodC strains.",J Zhang 2020,2020,4 genes,Zhang-2020-Four superoxide dismutases of Bacil,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15623,PHI:9971,UniProt,A0A063CKB3,GenBank,QEF19351,,,09,sodC,,,,,,,1396,Bacillus cereus,,0-9,,moths,29058,Helicoverpa armigera (related: cotton bollworm),,,,,superoxide dismutase,,,,reduced virulence,,,,,,reduced,,,,no,paraquat; menadione (vitamin K3),paraquat: CHEBI:34905; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,31897767,PubMed,10.1007/s11274-019-2786-7,World J Microbiol Biotechnol. 2020 Jan 2;36(1):12,gwangbio@henu.edu.cn,"Mutant lacking all four sod genesc aused a reduced death rate of H. armigera of 46.70%, which was slightly higher than that caused by the ΔsodS and ΔsodC strains.",J Zhang 2020,2020,4 genes,Zhang-2020-Four superoxide dismutases of Bacil,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15624,PHI:9968,UniProt,Q81LW0,GenBank,QEF18766,,,09,sodA1,,,,,,PHI:9969; PHI:9970; PHI:9971,1396,Bacillus cereus,,0-9,,moths,29058,Helicoverpa armigera (related: cotton bollworm),,,,,superoxide dismutase,,,,reduced virulence,,,,,,reduced,,,,no,paraquat; menadione (vitamin K3),paraquat: CHEBI:34905; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,31897767,PubMed,10.1007/s11274-019-2786-7,World J Microbiol Biotechnol. 2020 Jan 2;36(1):12,gwangbio@henu.edu.cn,"Mutant lacking all four sod genesc aused a reduced death rate of H. armigera of 46.70%, which was slightly higher than that caused by the ΔsodS and ΔsodC strains.",J Zhang 2020,2020,4 genes,Zhang-2020-Four superoxide dismutases of Bacil,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15625,PHI:9969,UniProt,Q814I6,GenBank,QEF19841,,,09,sodA2,,,,,,PHI:9968; PHI:9970; PHI:9971,1396,Bacillus cereus,,0-9,,moths,29058,Helicoverpa armigera (related: cotton bollworm),,,,,superoxide dismutase,,,,reduced virulence,,,,,,reduced,,,,no,paraquat; menadione (vitamin K3),paraquat: CHEBI:34905; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,31897767,PubMed,10.1007/s11274-019-2786-7,World J Microbiol Biotechnol. 2020 Jan 2;36(1):12,gwangbio@henu.edu.cn,"Mutant lacking all four sod genesc aused a reduced death rate of H. armigera of 46.70%, which was slightly higher than that caused by the ΔsodS and ΔsodC strains.",J Zhang 2020,2020,4 genes,Zhang-2020-Four superoxide dismutases of Bacil,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15626,PHI:9970,UniProt,no data found,GenBank,QEF16174,,,09,sodS,,,,,,PHI:9968; PHI:9969; PHI:9971,1396,Bacillus cereus,,0-9,,moths,29058,Helicoverpa armigera (related: cotton bollworm),,,,,superoxide dismutase,,,,reduced virulence,,,,,,reduced,,,,no,paraquat; menadione (vitamin K3),paraquat: CHEBI:34905; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,31897767,PubMed,10.1007/s11274-019-2786-7,World J Microbiol Biotechnol. 2020 Jan 2;36(1):12,gwangbio@henu.edu.cn,"Mutant lacking all four sod genesc aused a reduced death rate of H. armigera of 46.70%, which was slightly higher than that caused by the ΔsodS and ΔsodC strains.",J Zhang 2020,2020,4 genes,Zhang-2020-Four superoxide dismutases of Bacil,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15627,PHI:9971,UniProt,A0A063CKB3,GenBank,QEF19351,,,09,sodC,,,,,,PHI:9968; PHI:9969; PHI:9970,1396,Bacillus cereus,,0-9,,moths,29058,Helicoverpa armigera (related: cotton bollworm),,,,,superoxide dismutase,,,,reduced virulence,,,,,,reduced,,,,no,paraquat; menadione (vitamin K3),paraquat: CHEBI:34905; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,31897767,PubMed,10.1007/s11274-019-2786-7,World J Microbiol Biotechnol. 2020 Jan 2;36(1):12,gwangbio@henu.edu.cn,"Mutant lacking all four sod genesc aused a reduced death rate of H. armigera of 46.70%, which was slightly higher than that caused by the ΔsodS and ΔsodC strains.",J Zhang 2020,2020,4 genes,Zhang-2020-Four superoxide dismutases of Bacil,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15628,PHI:9972,UniProt,Q5HJX6,GenBank,AAW37408,,,COL,yycG,,,,,,,1280,Staphylococcus aureus,1413495,MRSA-118,osteomyelitis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,bone,sensory box histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: overexpression,,,YVS,31831035,PubMed,10.1186/s13018-019-1508-z,J Orthop Surg Res. 2019 Dec 12;14(1):433,leilei@scu.edu.cn,ASyycG suppressed the invasive ability and pathogenicity of the strain in vivo using an SPF (specific pathogen free) rat model.,S Wu 2019,2019,1 gene,Wu-2019-Virulence of methicillin-resistant Sta,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15629,PHI:9973,UniProt,A0A1C3YLQ3,GenBank,XP_011328484,,,PH-1; NRRL 31084,srp2 (FGSG_09282),chromosome 4,,,srp1,UniProt: I1RZL5; GenBank: CEF75159,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,uncharacterized protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2); sodium dodecyl sulphate (SDS); Congo red,hydrogen peroxide (H2O2): CHEBI:16240; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32040734,PubMed,10.1007/s00294-020-01054-2,Curr Genet. 2020 Feb 10,jinrong@purdue.edu,"FgSrp2 regulates vegetative growth, sexual reproduction and pre-mRNA processing by interacting with FgSrp1.",Y Zhang 2020,2020,2 genes,Zhang-2020-The SR-protein FgSrp2 regulates veg,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15630,PHI:9973,UniProt,A0A1C3YLQ3,GenBank,XP_011328484,,,PH-1; NRRL 31084,srp2 (FGSG_09282),chromosome 4,,,srp1,UniProt: I1RZL5; GenBank: CEF75159,PHI:9974,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,uncharacterized protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2); sodium dodecyl sulphate (SDS); Congo red,hydrogen peroxide (H2O2): CHEBI:16240; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32040734,PubMed,10.1007/s00294-020-01054-2,Curr Genet. 2020 Feb 10,jinrong@purdue.edu,"FgSrp2 regulates vegetative growth, sexual reproduction and pre-mRNA processing by interacting with FgSrp1.",Y Zhang 2020,2020,2 genes,Zhang-2020-The SR-protein FgSrp2 regulates veg,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15631,PHI:9974,UniProt,I1RZL5,GenBank,CEF75159,,,PH-1,srp1,chromosome 1,,,srp2,UniProt: A0A1C3YLQ3; GenBank: XP_011328484,PHI:9973,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spikelet,RRM domain-containing protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2); sodium dodecyl sulphate (SDS); Congo red,hydrogen peroxide (H2O2): CHEBI:16240; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32040734,PubMed,10.1007/s00294-020-01054-2,Curr Genet. 2020 Feb 10,jinrong@purdue.edu,"FgSrp2 regulates vegetative growth, sexual reproduction and pre-mRNA processing by interacting with FgSrp1.",Y Zhang 2020,2020,2 genes,Zhang-2020-The SR-protein FgSrp2 regulates veg,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15632,PHI:9975,UniProt,no data found,GenBank,,,,,SsPI-1,,,,,,,1307,Streptococcus suis,391295,05ZYH33,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),,,,lung; spleen; liver; heart; kidney,chromosomal pathogenicity island,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31817637,PubMed,10.3390/pathogens8040287,Pathogens. 2019 Dec 6;8(4),liming@tmmu.edu.cn,The SsPI-1 mutant causes no significant pathological lesions and exhibits an impaired ability to induce proinflammatory cytokine production.,Y Zhao 2019,2019,1 gene,Zhao-2019-The Impact of SsPI-1 Deletion on Str,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15633,PHI:9975,UniProt,no data found,GenBank,,,,,SsPI-1,,,,,,,1307,Streptococcus suis,391295,05ZYH33,meningitis; septicemia; arthritis; pneumonia (pig),primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,chromosomal pathogenicity island,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31817637,PubMed,10.3390/pathogens8040287,Pathogens. 2019 Dec 6;8(4),liming@tmmu.edu.cn,Deletion of SsPI-1 significantly reduces adherence of S. suis to epithelial cells. laryngeal epithelial cells,Y Zhao 2019,2019,1 gene,Zhao-2019-The Impact of SsPI-1 Deletion on Str,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 15634,PHI:9979,UniProt,A0A0K0GP65,GenBank,ACD60893,,,PXO99A,leuB (PXO_02610),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,3-isopropylmalate dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15635,PHI:9980,UniProt,B2SNH3,GenBank,ACD60895,,,PXO99A,leuD (PXO_02612),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,3-isopropylmalate dehydratase small subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15636,PHI:9981,UniProt,B2SNH4,GenBank,ACD60896,,,PXO99A,leuC (PXO_02613),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,3-isopropylmalate dehydratase large subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15637,PHI:9982,UniProt,A0A0K0GKF0,GenBank,ACD58967,,,PXO99A,thrC (PXO_00822),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,threonine synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15638,PHI:9983,UniProt,A0A0K0GKU8,GenBank,ACD58960,,,PXO99A,hisD (PXO_00833),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,histidinol dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15639,PHI:9984,UniProt,B2SL03,GenBank,ACD57280,,,PXO99A,trpC (PXO_04004),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,indole-3-glycerol phosphate synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15640,PHI:9985,UniProt,B2SHW2,GenBank,ACD58622,,,PXO99A,argH (PXO_00346),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,argininosuccinate lyase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15641,PHI:9986,UniProt,A0A0K0GQB7,GenBank,ACD61061,,,PXO99A,metB (PXO_03157),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,cystathionine gamma-synthase (CGS) (O-succinylhomoserine(thiol)-lyase),,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15642,PHI:9987,UniProt,A0A0K0GPX0,GenBank,ACD61146,,,PXO99A,lrp (PXO_03072),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,leucine responsive regulatory protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15643,PHI:9988,UniProt,B2SNG5,GenBank,ACD60887,,,PXO99A,ilvC (PXO_02605),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,ketol-acid reductoisomerase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15644,PHI:9989,UniProt,A0A0K0GPI8,GenBank,ACD60708,,,PXO99A,aspC (PXO_02420),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,aspartate aminotransferase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31847108,PubMed,10.3390/microorganisms7120693,Microorganisms. 2019 Dec 13;7(12),chun_xia_li@126.com,Limiting amino acid availability in rice leaves may restrict Xoo growth in planta.,T Li 2019,2019,11 genes,Li-2019-Biosynthesis of Amino Acids in Xanthom,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15645,PHI:9990,UniProt,P77432,GenBank,AAC74584,,,K-12,lsrK,,,,,,,562,Escherichia coli,,APEC94,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; spleen; kidney,autoinducer-2 kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31831050,PubMed,10.1186/s13567-019-0725-0,Vet Res. 2019 Dec 12;50(1):109,hanxgan@163.com,The lsr operon mutant was found to be defective in motility and Autoinducer-2 (AI-2) uptake.,J Zuo 2019,2019,8 genes,Zuo-2019-Lsr operon is associated with AI-2 tr,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15646,PHI:9991,UniProt,P76141,GenBank,AAC74585,,,K-12,lsrR,,,,,,,562,Escherichia coli,,APEC94,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; spleen; kidney,DNA-binding transcriptional repressor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31831050,PubMed,10.1186/s13567-019-0725-0,Vet Res. 2019 Dec 12;50(1):109,hanxgan@163.com,The lsr operon mutant was found to be defective in motility and Autoinducer-2 (AI-2) uptake.,J Zuo 2019,2019,8 genes,Zuo-2019-Lsr operon is associated with AI-2 tr,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15647,PHI:9992,UniProt,P77257,GenBank,AAC74586,,,K-12,lsrA,,,,,,,562,Escherichia coli,,APEC94,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; spleen; kidney,autoinducer-2 ABC transporter ATP binding subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31831050,PubMed,10.1186/s13567-019-0725-0,Vet Res. 2019 Dec 12;50(1):109,hanxgan@163.com,The lsr operon mutant was found to be defective in motility and Autoinducer-2 (AI-2) uptake.,J Zuo 2019,2019,8 genes,Zuo-2019-Lsr operon is associated with AI-2 tr,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15648,PHI:9993,UniProt,P77672,GenBank,AAC74587,,,K-12,lsrC,,,,,,,562,Escherichia coli,,APEC94,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; spleen; kidney,autoinducer-2 ABC transporter membrane subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31831050,PubMed,10.1186/s13567-019-0725-0,Vet Res. 2019 Dec 12;50(1):109,hanxgan@163.com,The lsr operon mutant was found to be defective in motility and Autoinducer-2 (AI-2) uptake.,J Zuo 2019,2019,8 genes,Zuo-2019-Lsr operon is associated with AI-2 tr,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15649,PHI:9994,UniProt,P0AFS1,GenBank,AAC74588,,,K-12,lsrD,,,,,,,562,Escherichia coli,,APEC94,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; spleen; kidney,autoinducer-2 ABC transporter membrane subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31831050,PubMed,10.1186/s13567-019-0725-0,Vet Res. 2019 Dec 12;50(1):109,hanxgan@163.com,The lsr operon mutant was found to be defective in motility and Autoinducer-2 (AI-2) uptake.,J Zuo 2019,2019,8 genes,Zuo-2019-Lsr operon is associated with AI-2 tr,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15650,PHI:9995,UniProt,P76142,GenBank,AAC74589,,,K-12,lsrB,,,,,,,562,Escherichia coli,,APEC94,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; spleen; kidney,autoinducer-2 ABC transporter periplasmic binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31831050,PubMed,10.1186/s13567-019-0725-0,Vet Res. 2019 Dec 12;50(1):109,hanxgan@163.com,The lsr operon mutant was found to be defective in motility and Autoinducer-2 (AI-2) uptake.,J Zuo 2019,2019,8 genes,Zuo-2019-Lsr operon is associated with AI-2 tr,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15651,PHI:9996,UniProt,P76143,GenBank,AAC74590,,,K-12,lsrF,,,,,,,562,Escherichia coli,,APEC94,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; spleen; kidney,"3-hydroxy-2,4-pentadione 5-phosphate thiolase",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31831050,PubMed,10.1186/s13567-019-0725-0,Vet Res. 2019 Dec 12;50(1):109,hanxgan@163.com,The lsr operon mutant was found to be defective in motility and Autoinducer-2 (AI-2) uptake.,J Zuo 2019,2019,8 genes,Zuo-2019-Lsr operon is associated with AI-2 tr,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15652,PHI:9997,UniProt,P64461,GenBank,AAC74591,,,K-12,lsrG,,,,,,,562,Escherichia coli,,APEC94,meningitis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; spleen; kidney,"(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31831050,PubMed,10.1186/s13567-019-0725-0,Vet Res. 2019 Dec 12;50(1):109,hanxgan@163.com,The lsr operon mutant was found to be defective in motility and Autoinducer-2 (AI-2) uptake.,J Zuo 2019,2019,8 genes,Zuo-2019-Lsr operon is associated with AI-2 tr,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15653,PHI:9998,UniProt,J9VRC4,GenBank,AFR94270,,,H99,atg1 (CNAG_05005),chromosome 4,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,ULK/ULK protein kinase,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15654,PHI:9999,UniProt,J9VFE3,GenBank,AFR93067,,,H99,atg2 (CNAG_06732),chromosome 2,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15655,PHI:10000,UniProt,J9VIW1,GenBank,AFR94148,,,H99,atg3 (CNAG_06892),chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,autophagy-related protein,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15656,PHI:10001,UniProt,J9VN57,GenBank,AFR94029,,,H99,atg4 (CNAG_02662),chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,cysteine protease,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15657,PHI:10002,UniProt,J9VWV8,GenBank,AFR98748,,,H99,atg5 (CNAG_06519),chromosome 13,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,autophagy protein,,,,reduced virulence,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15658,PHI:10003,UniProt,J9VX66,GenBank,AFR97976,,,H99,atg6 (CNAG_01773),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,beclin 1,,,,loss of pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15659,PHI:10004,UniProt,J9VS05,GenBank,AFR97257,,,H99,atg7 (CNAG_04538),chromosome 9,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,ubiquitin-like modifier-activating enzyme,,,,reduced virulence,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15660,PHI:10005,UniProt,J9VF50,GenBank,AFR92947,,,H99,atg8 (CNAG_00816),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,autophagy-related protein/ microtubule binding protein,,,,reduced virulence,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15661,PHI:10006,UniProt,J9VKC3,GenBank,AFR94698,,,H99,atg9 (CNAG_01445),chromosome 5,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,autophagy-related protein,,,,reduced virulence,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15662,PHI:10007,UniProt,J9VKD8,GenBank,AFR94718,,,H99,atg11 (CNAG_01424),chromosome 5,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,hypothetical protein,,,,loss of pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15663,PHI:10008,UniProt,J9VV55,GenBank,AFR95590,,,H99,atg12 (CNAG_07645),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,ubiquitin-like protein,,,,reduced virulence,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15664,PHI:10009,UniProt,J9VK04,GenBank,AFR92909,,,H99,atg13 (CNAG_00778),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,autophagy-related protein,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15665,PHI:10010,UniProt,J9VFI3,GenBank,AFR93112,,,H99,atg14-03 (CNAG_03608),chromosome 2,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,hypothetical protein,,,,loss of pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15666,PHI:10011,UniProt,J9W3Z8,GenBank,AFR98925,,,H99,atg14-05 (CNAG_05500),chromosome 14,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15667,PHI:10012,UniProt,J9W153,GenBank,AFR97805,,,H99,atg15 (CNAG_01601),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,lipase,,,,reduced virulence,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15668,PHI:10013,UniProt,J9VL02,GenBank,AFR94116,,,H99,atg16 (CNAG_02576),chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15669,PHI:10014,UniProt,J9VM57,GenBank,AFR95557,,,H99,atg18 (CNAG_02269),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,autophagy-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15670,PHI:10015,UniProt,J9VN05,GenBank,AFR93959,,,H99,atg20 (CNAG_02730),chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,sorting nexin-41,,,,reduced virulence,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15671,PHI:10016,UniProt,J9VPS1,GenBank,AFR96263,,,H99,atg22 (CNAG_07685),chromosome 7,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,autophagy-related protein,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15672,PHI:10017,UniProt,J9VYM9,GenBank,AFR97759,,,H99,atg24 (CNAG_01554),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,sorting nexin-4,,,,reduced virulence,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15673,PHI:10018,UniProt,P0CN91,GenBank,EAL22129,,,B-3501A,atg26 (CNAG_12261),chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,sterol 3-beta-glucosyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15674,PHI:10019,UniProt,J9VRN9,GenBank,AFR97137,,,H99,atg27 (CNAG_04406),chromosome 9,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15675,PHI:10020,UniProt,J9VM91,GenBank,AFR95592,,,H99,atg101 (CNAG_07646),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,32038502,PubMed,10.3389/fmicb.2019.02690,Front Microbiol. 2019 Nov 26;10:2690,zhu11187@bnu.edu.cn,Approximately half of the atg1 strains displayed higher sensitivity to 1.5 M NaCl and remarkably lower virulence in the Galleria mellonella model than the wild type.,X Zhao 2019,2019,23 genes,Zhao-2019-Conserved Autophagy Pathway Contribu,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15676,PHI:10021,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,extracellular signal-regulated kinase 1,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15677,PHI:10022,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15678,PHI:10023,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15679,PHI:10024,UniProt,Q92207,GenBank,AOW27369,,,SC5314,hog1,chromosome 2,,,,,,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15680,PHI:10021,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,PHI:10022,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,extracellular signal-regulated kinase 1,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15681,PHI:10022,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,PHI:10021,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15682,PHI:10021,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome R,,,,,PHI:10023,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,extracellular signal-regulated kinase 1,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15683,PHI:10023,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,PHI:10021,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15684,PHI:10021,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,PHI:10024,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,extracellular signal-regulated kinase 1,,,cell wall integrity (CWI) pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15685,PHI:10024,UniProt,Q92207,GenBank,AOW27369,,,SC5314,hog1,chromosome 2,,,,,PHI:10021,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15686,PHI:10022,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,PHI:10024,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15687,PHI:10024,UniProt,Q92207,GenBank,AOW27369,,,SC5314,hog1,chromosome 2,,,,,PHI:10022,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15688,PHI:10022,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,PHI:10023,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15689,PHI:10023,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,PHI:10022,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15690,PHI:10024,UniProt,Q92207,GenBank,AOW27369,,,SC5314,hog1,chromosome 2,,,,,PHI:10023,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15691,PHI:10023,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,PHI:10024,5476,Candida albicans,,CAF2,systemic candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,oral epithelial cell,mitogen-activated protein kinase,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31881718,PubMed,10.3390/microorganisms8010048,Microorganisms. 2019 Dec 25;8(1),inescorreia351@gmail.com,"The Mkc1 cell wall integrity (CWI) and Cek1 pathways, were both required for oral epithelial damage.",I Correia 2019,2019,4 genes,Correia-2019-Cooperative Role of MAPK Pathways,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15692,PHI:10025,UniProt,no data found,GenBank,,,,,eps1 (Bc5279-Bc5263),,,,,,,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,exopolysaccharide production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility.",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15693,PHI:10026,UniProt,no data found,GenBank,,,,,eps2 (Bc1583-Bc1591),,,,,,,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,capsular polysaccharide,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility.",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15694,PHI:10025,UniProt,no data found,GenBank,,,,,eps1 (Bc5279-Bc5263),,,,,,PHI:10026,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,exopolysaccharide production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility.",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15695,PHI:10026,UniProt,no data found,GenBank,,,,,eps2 (Bc1583-Bc1591),,,,,,PHI:10025,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,capsular polysaccharide,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility.",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15696,PHI:10025,UniProt,no data found,GenBank,,,,,eps1 (Bc5279-Bc5263),,,,,,,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,primates,9606,Homo sapiens (related: human),MDA cell line,,,epithelial cell,exopolysaccharide production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility.",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15697,PHI:10026,UniProt,no data found,GenBank,,,,,eps2 (Bc1583-Bc1591),,,,,,,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,primates,9606,Homo sapiens (related: human),MDA cell line,,,epithelial cell,capsular polysaccharide,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility.",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15698,PHI:10025,UniProt,no data found,GenBank,,,,,eps1 (Bc5279-Bc5263),,,,,,PHI:10026,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,primates,9606,Homo sapiens (related: human),MDA cell line,,,epithelial cell,exopolysaccharide production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility.",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15699,PHI:10026,UniProt,no data found,GenBank,,,,,eps2 (Bc1583-Bc1591),,,,,,PHI:10025,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,primates,9606,Homo sapiens (related: human),MDA cell line,,,epithelial cell,capsular polysaccharide,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility.",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15700,PHI:10025,UniProt,no data found,GenBank,,,,,eps1 (Bc5279-Bc5263),,,,,,,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,exopolysaccharide production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility. larval GI tract",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15701,PHI:10026,UniProt,no data found,GenBank,,,,,eps2 (Bc1583-Bc1591),,,,,,,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,capsular polysaccharide,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility. larval GI tract",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15702,PHI:10025,UniProt,no data found,GenBank,,,,,eps1 (Bc5279-Bc5263),,,,,,PHI:10026,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,exopolysaccharide production,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility. larval GI tract",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15703,PHI:10026,UniProt,no data found,GenBank,,,,,eps2 (Bc1583-Bc1591),,,,,,PHI:10025,1396,Bacillus cereus,,ATCC 14579,diarrhea; nausea; vomiting,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,capsular polysaccharide,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31969664,PubMed,10.1038/s41598-020-57970-3,Sci Rep. 2020 Jan 22;10(1):1000,diego_romero@uma.es,"Eps2 region was involved in bacterial adhesion to surfaces, cell-to-cell interaction, cellular aggregation and bioflm formation, while the eps1 region appeared to be involved in a kind of social bacterial motility. larval GI tract",J Caro-Astorga 2020,2020,2 genes,Caro-Astorga-2020-Two genomic regions encoding,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15704,PHI:10027,UniProt,no data found,GenBank,,,,,PpCRN7,,,,,,,4792,Phytophthora nicotianae,,IAC_01/95.1,black shank (tobacco),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31810451,PubMed,10.1186/s12870-019-2129-8,BMC Plant Biol. 2019 Dec 6;19(1):544,marcos@ccsm.br,Transient expression of PpCRN7 and PpCRN20 increased N. benthamiana susceptibility. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',H J Maximo 2019,2019,2 genes,Maximo-2019-PpCRN7 and PpCRN20 of Phythophthor,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15705,PHI:10028,UniProt,no data found,GenBank,,,,,PpCRN20,,,,,,,4792,Phytophthora nicotianae,,IAC_01/95.1,black shank (tobacco),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31810451,PubMed,10.1186/s12870-019-2129-8,BMC Plant Biol. 2019 Dec 6;19(1):544,marcos@ccsm.br,Transient expression of PpCRN7 and PpCRN20 increased N. benthamiana susceptibility. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae',H J Maximo 2019,2019,2 genes,Maximo-2019-PpCRN7 and PpCRN20 of Phythophthor,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15706,PHI:10037,UniProt,Q9KM66,GenBank,AAF96425,,,N16961,cqsS,chromosome II,,,,,PHI:10038; PHI:10039; PHI:10040,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,sensor histidine kinase/response regulator,,,,reduced virulence,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene mutation,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15707,PHI:10038,UniProt,Q9KLK7,GenBank,AAF96635,,,N16961,luxQ,chromosome II,,,,,PHI:10037; PHI:10039; PHI:10040,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,autoinducer 2 sensor kinase/phosphatase,,,,reduced virulence,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene mutation,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15708,PHI:10039,UniProt,no data found,GenBank,,,,,cqsR,,,,,,PHI:10037; PHI:10038; PHI:10040,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,quorum sensing receptor,,,,reduced virulence,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene mutation,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15709,PHI:10040,UniProt,no data found,GenBank,,,,,vpsS,,,,,,PHI:10037; PHI:10038; PHI:10039,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,quorum sensing receptor,,,,reduced virulence,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene mutation,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15710,PHI:10037,UniProt,Q9KM66,GenBank,AAF96425,,,N16961,cqsS,,,,,,PHI:10038; PHI:10040,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,sensor histidine kinase/response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene mutation,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15711,PHI:10038,UniProt,Q9KLK7,GenBank,AAF96635,,,N16961,luxQ,,,,,,PHI:10037; PHI:10040,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,autoinducer 2 sensor kinase/phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene mutation,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15712,PHI:10040,UniProt,no data found,GenBank,,,,,vpsS,,,,,,PHI:10037; PHI:10038,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,quorum sensing receptor,,,,unaffected pathogenicity,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene mutation,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15713,PHI:10037,UniProt,Q9KM66,GenBank,AAF96425,,,N16961,cqsS,,,,,,PHI:10038; PHI:10040; PHI:10039,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,sensor histidine kinase/response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene deletion: full,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15714,PHI:10038,UniProt,Q9KLK7,GenBank,AAF96635,,,N16961,luxQ,,,,,,PHI:10037; PHI:10040; PHI:10039,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,autoinducer 2 sensor kinase/phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene deletion: full,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15715,PHI:10040,UniProt,no data found,GenBank,,,,,vpsS,,,,,,PHI:10037; PHI:10038; PHI:10039,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,quorum sensing receptor,,,,unaffected pathogenicity,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene deletion: full,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15716,PHI:10039,UniProt,no data found,GenBank,,,,,cqsR,,ΔcqsS ΔluxQ ΔvpsS cqsR+,,,,PHI:10037; PHI:10038; PHI:10040,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,quorum sensing receptor,,,,reduced virulence,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,other evidence: constitutive expression,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15717,PHI:10039,UniProt,no data found,GenBank,,,,,cqsR,,cqsR D171V,,,,,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,quorum sensing receptor,,,,reduced virulence,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene mutation,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15718,PHI:10041,UniProt,Q60153,GenBank,AAF93991,,,N16961,tcpa,chromosome I,,,,,,666,Vibrio cholerae,948564,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine; large intestine,toxin coregulated pilin,,,,reduced virulence,,,,,,,,,,no,ethanolamine; serinol; L-alaninol; D-alaninol,ethanolamine: CHEBI:16000; serinol cas no.: CAS:534-03-2; L-alaninol cas no.: CAS:2749-11-3; D-alaninol cas no.: CAS:35320-23-1,,,,,gene mutation,,,YVS,32059031,PubMed,10.1371/journal.ppat.1008313,PLoS Pathog. 2020 Feb 14;16(2):e1008313,wai-leung.ng@tufts.edu,The mutants expressing only CqsR without the other three QS receptors were defective in colonizing the host large intestine.,S Watve 2020,2020,5 genes,Watve-2020-Parallel quorum-sensing system in V,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15719,PHI:10042,UniProt,no data found,GenBank,AZA30841,,,IP2666pIB1,cnfY,,,,,,,633,Yersinia pseudotuberculosis,,YP216,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,mesenteric lymph node; spleen; liver,cytotoxic necrotizing factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31951643,PubMed,10.1371/journal.ppat.1008184,PLoS Pathog. 2020 Jan 17;16(1):e1008184,franz.narberhaus@rub.de,Y. pseudotuberculosis strains carrying stabilized RNA thermometer variants upstream of cnfY were avirulent and attenuated in their ability to disseminate into mesenteric lymph nodes and spleen.,C Twittenhoff 2020,2020,1 gene,Twittenhoff-2020-An RNA thermometer dictates p,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15720,PHI:10044,UniProt,Q9UQY5,GenBank,AF193614_1,,,a2b3,kpp2,,,,rok1,UniProt: no data found; GenBank: no data found,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,mitogen-activated protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31848283,PubMed,10.1128/mBio.02756-19,mBio. 2019 Dec 17;10(6),kheimel@gwdg.de,Kpp2 was required for the mating process and important for appressoria formation but dispensable for pathogenic development in planta.,L Schmitz 2019,2019,2 genes,Schmitz-2019-The Unfolded Protein Response Reg,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15721,PHI:10044,UniProt,Q9UQY5,GenBank,AF193614_1,,,a2b3,kpp2,,constructs expressing kpp2 under the control of the conditional promoters PUMAG_12184 and PUMAG_03597,,rok1,UniProt: no data found; GenBank: no data found,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,mitogen-activated protein kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: conditional gene expression,,,YVS,31848283,PubMed,10.1128/mBio.02756-19,mBio. 2019 Dec 17;10(6),kheimel@gwdg.de,Kpp2 was required for the mating process and important for appressoria formation but dispensable for pathogenic development in planta.,L Schmitz 2019,2019,2 genes,Schmitz-2019-The Unfolded Protein Response Reg,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15722,PHI:10045,UniProt,no data found,GenBank,,,,,rok1,,cib1s-expressing,,kpp2,UniProt: Q9UQY5; GenBank: AF193614_1,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,dual specificity phosphatase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31848283,PubMed,10.1128/mBio.02756-19,mBio. 2019 Dec 17;10(6),kheimel@gwdg.de,"Deletion of the dual specificity phosphatase rok1 fully suppressed UPR-dependent inhibition of Kpp2 phosphorylation, formation of infectious filaments and fungal virulence.",L Schmitz 2019,2019,2 genes,Schmitz-2019-The Unfolded Protein Response Reg,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15723,PHI:10046,UniProt,P40720,GenBank,AAL20388,,,LT2,fumA,,,,,,PHI:10047; PHI:10048,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"fumarate hydratase class I, aerobic",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15724,PHI:10047,UniProt,Q8ZKE2,GenBank,AAL23124,,,LT2,fumB,,,,,,PHI:10046; PHI:10048,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class I,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15725,PHI:10048,UniProt,Q8ZPL7,GenBank,AAL20389,,,LT2,fumC,,,,,,PHI:10046; PHI:10047,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15726,PHI:10046,UniProt,P40720,GenBank,AAL20388,,,LT2,fumA,,,,,,PHI:10047; PHI:10048; PHI:10049,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"fumarate hydratase class I, aerobic",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15727,PHI:10047,UniProt,Q8ZKE2,GenBank,AAL23124,,,LT2,fumB,,,,,,PHI:10046; PHI:10048; PHI:10049,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class I,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15728,PHI:10048,UniProt,Q8ZPL7,GenBank,AAL20389,,,LT2,fumC,,,,,,PHI:10046; PHI:10047; PHI:10049,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15729,PHI:10049,UniProt,P0A2D5,GenBank,AAL20832,,,LT2,cheY,,,,,,PHI:10046; PHI:10047; PHI:10048,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,chemotaxis regulator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15730,PHI:10046,UniProt,P40720,GenBank,AAL20388,,,LT2,fumA,,,,,,PHI:10047; PHI:10048; PHI:10050,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"fumarate hydratase class I, aerobic",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15731,PHI:10047,UniProt,Q8ZKE2,GenBank,AAL23124,,,LT2,fumB,,,,,,PHI:10046; PHI:10048; PHI:10050,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class I,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15732,PHI:10048,UniProt,Q8ZPL7,GenBank,AAL20389,,,LT2,fumC,,,,,,PHI:10046; PHI:10047; PHI:10050,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15733,PHI:10050,UniProt,P07800,GenBank,AAL20831,,,LT2,cheZ,,,,,,PHI:10046; PHI:10047; PHI:10048,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,protein phosphatase/ chemotactic response protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15734,PHI:10046,UniProt,P40720,GenBank,AAL20388,,,LT2,fumA,,,,,,PHI:10047; PHI:10048; PHI:10051,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"fumarate hydratase class I, aerobic",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15735,PHI:10047,UniProt,Q8ZKE2,GenBank,AAL23124,,,LT2,fumB,,,,,,PHI:10046; PHI:10048; PHI:10051,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class I,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15736,PHI:10048,UniProt,Q8ZPL7,GenBank,AAL20389,,,LT2,fumC,,,,,,PHI:10046; PHI:10047; PHI:10051,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15737,PHI:10051,UniProt,P05416,GenBank,AAL22395,,,LT2,glgA,,,,,,PHI:10046; PHI:10047; PHI:10048,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,glycogen synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15738,PHI:10046,UniProt,P40720,GenBank,AAL20388,,,LT2,fumA,,,,,,PHI:10047; PHI:10048; PHI:10051; PHI:10049,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"fumarate hydratase class I, aerobic",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15739,PHI:10047,UniProt,Q8ZKE2,GenBank,AAL23124,,,LT2,fumB,,,,,,PHI:10046; PHI:10048; PHI:10051; PHI:10049,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class I,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15740,PHI:10048,UniProt,Q8ZPL7,GenBank,AAL20389,,,LT2,fumC,,,,,,PHI:10046; PHI:10047; PHI:10051; PHI:10049,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15741,PHI:10051,UniProt,P05416,GenBank,AAL22395,,,LT2,glgA,,,,,,PHI:10046; PHI:10047; PHI:10048; PHI:10049,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,glycogen synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15742,PHI:10049,UniProt,P0A2D5,GenBank,AAL20832,,,LT2,cheY,,,,,,PHI:10046; PHI:10047; PHI:10048; PHI:10051,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,chemotaxis regulator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15743,PHI:10046,UniProt,P40720,GenBank,AAL20388,,,LT2,fumA,,,,,,PHI:10047; PHI:10048; PHI:10051; PHI:10050,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"fumarate hydratase class I, aerobic",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15744,PHI:10047,UniProt,Q8ZKE2,GenBank,AAL23124,,,LT2,fumB,,,,,,PHI:10046; PHI:10048; PHI:10051; PHI:10050,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class I,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15745,PHI:10048,UniProt,Q8ZPL7,GenBank,AAL20389,,,LT2,fumC,,,,,,PHI:10046; PHI:10047; PHI:10051; PHI:10050,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,fumarate hydratase class II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15746,PHI:10051,UniProt,P05416,GenBank,AAL22395,,,LT2,glgA,,,,,,PHI:10046; PHI:10047; PHI:10048; PHI:10050,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,glycogen synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15747,PHI:10050,UniProt,P07800,GenBank,AAL20831,,,LT2,chez,,,,,,PHI:10046; PHI:10047; PHI:10048; PHI:10051,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain NCTC 12023,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,chemotaxis regulator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31826974,PubMed,10.1128/mSphere.00796-19,mSphere. 2019 Dec 11;4(6),Janina.Noster@biologie.uni-osnabrueck.de,The increased phagocytic uptake of fumarase-deficient S. Typhimurium was due to enhanced CCW flagellar rotation and partially depended on glycogen synthesis.,J Noster 2019,2019,6 genes,Noster-2019-Blocks in Tricarboxylic Acid Cycle,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15748,PHI:10052,UniProt,A0A0F6B5P2,GenBank,ACY89836,,,14028S,STM14_RS15195 (srlA),,,,,,PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,PTS sorbitol transporter subunit IIC,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15749,PHI:10053,UniProt,A0A0F6B5P3,GenBank,ACY89837,,,14028S,STM14_RS15200 (srlE),,,,,,PHI:10052; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,PTS sorbitol transporter subunit IIB,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15750,PHI:10054,UniProt,A0A0F6B5P4,GenBank,ACY89838,,,14028S,STM14_RS15205 (slrB),,,,,,PHI:10052; PHI:10053; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,PTS glucitol/sorbitol transporter subunit IIA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15751,PHI:10055,UniProt,A0A0F6B5P5,GenBank,ACY89839,,,14028S,STM14_RS15210 (srlD),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,sorbitol-6-phosphate dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15752,PHI:10056,UniProt,A0A0F6B5P6,GenBank,ACY89840,,,14028S,STM14_RS15215 (gutM),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15753,PHI:10057,UniProt,no data found,GenBank,,,,,STM14_RS15220,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,glucitol operon transcriptional repressor: DeoR family,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15754,PHI:10058,UniProt,A0A0F6B5P8,GenBank,ACY89842,,,14028S,STM14_RS15225,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,arabinose 5-phosphate isomerase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15755,PHI:10059,UniProt,A0A0F6B5P9,GenBank,ACY89843,,,14028S,STM14_RS15230,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,NorR family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15756,PHI:10060,UniProt,A0A0F6B5Q0,GenBank,ACY89844,,,14028S,STM14_RS15235,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,anaerobic nitric oxide reductase flavorubredoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15757,PHI:10061,UniProt,A0A0F6B5Q1,GenBank,ACY89845,,,14028S,STM14_RS15240,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,NADH:flavorubredoxin reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15758,PHI:10062,UniProt,A0A0F6B5Q2,GenBank,ACY89846,,,14028S,STM14_RS15245,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,carbamoyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15759,PHI:10063,UniProt,A0A0F6B5Q4,GenBank,ACY89848,,,14028S,STM14_RS15250,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,electron transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15760,PHI:10064,UniProt,A0A0F6B5Q6,GenBank,ACY89850,,,14028S,STM14_RS15255,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15761,PHI:10065,UniProt,A0A0F6B5Q8,GenBank,ACY89852,,,14028S,STM14_RS15260,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hydrogenase maturation peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15762,PHI:10066,UniProt,A0A0F6B5Q9,GenBank,ACY89853,,,14028S,STM14_RS15265,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,formate hydrogenlyase maturation protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15763,PHI:10067,UniProt,A0A0F6B5R0,GenBank,ACY89854,,,14028S,STM14_RS15270,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,NADH-quinone oxidoreductase subunit,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15764,PHI:10068,UniProt,A0A0F6B5R1,GenBank,ACY89855,,,14028S,STM14_RS15275,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,formate hydrogenlyase complex iron-sulfur subunit,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15765,PHI:10069,UniProt,A0A0F6B5R2,GenBank,ACY89856,,,14028S,STM14_RS15280,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,formate hydrogenlyase subunit 5,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15766,PHI:10070,UniProt,A0A0F6B5R3,GenBank,ACY89857,,,14028S,STM14_RS15285,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,formate hydrogenlyase subunit 4,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15767,PHI:10071,UniProt,A0A0F6B5R4,GenBank,ACY89858,,,14028S,STM14_RS15290,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,formate hydrogenlyase subunit 3,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15768,PHI:10072,UniProt,A0A0F6B5R5,GenBank,ACY89859,,,14028S,STM14_RS15295,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,formate hydrogenlyase subunit 2,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15769,PHI:10073,UniProt,A0A0F6B5R6,GenBank,ACY89860,,,14028S,STM14_RS15300,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,formate hydrogenlyase regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15770,PHI:10074,UniProt,A0A0F6B5R8,GenBank,ACY89862,,,14028S,STM14_RS15305,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hydrogenase maturation nickel metallochaperone,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15771,PHI:10075,UniProt,A0A0F6B5S0,GenBank,ACY89864,,,14028S,STM14_RS15310,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hydrogenase nickel incorporation protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15772,PHI:10076,UniProt,A0A0F6B5S1,GenBank,ACY89865,,,14028S,STM14_RS15315,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hydrogenase assembly chaperone,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15773,PHI:10077,UniProt,A0A0F6B5S2,GenBank,ACY89866,,,14028S,STM14_RS15320,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hydrogenase formation protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15774,PHI:10078,UniProt,A0A0F6B5S3,GenBank,ACY89867,,,14028S,STM14_RS15325,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hydrogenase expression/formation protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15775,PHI:10079,UniProt,A0A0F6B5S4,GenBank,ACY89868,,,14028S,STM14_RS15330,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,formate hydrogenlyase transcriptional activator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15776,PHI:10080,UniProt,no data found,GenBank,,,,,STM14_RS15335,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,nitrous oxide-stimulated promoter family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15777,PHI:10081,UniProt,A0A0F6B5S6,GenBank,ACY89870,,,14028S,STM14_RS15340,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,iron ABC transporter substrate-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15778,PHI:10082,UniProt,A0A0F6B5S8,GenBank,ACY89872,,,14028S,STM14_RS15345,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,manganese/iron ABC transporter ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15779,PHI:10083,UniProt,A0A0F6B5S9,GenBank,ACY89873,,,14028S,STM14_RS15350,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,iron ABC transporter permease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15780,PHI:10084,UniProt,A0A0F6B5T0,GenBank,ACY89874,,,14028S,STM14_RS15355,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,iron ABC transporter permease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15781,PHI:10085,UniProt,A0A0F6B5T1,GenBank,ACY89875,,,14028S,STM14_RS15360,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,putative inner membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15782,PHI:10086,UniProt,no data found,GenBank,,,,,STM14_RS15365,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15783,PHI:10087,UniProt,A0A0F6B5T3,GenBank,ACY89877,,,14028S,STM14_RS15370,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,AraC family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15784,PHI:10088,UniProt,A0A0F6B5T5,GenBank,ACY89879,,,14028S,STM14_RS15375,,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15785,PHI:10089,UniProt,A0A0F6B5T7,GenBank,ACY89881,,,14028S,STM14_RS15380 (orgC),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system effector protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15786,PHI:10090,UniProt,A0A0F6B5T8,GenBank,ACY89882,,,14028S,STM14_RS15385 (orgB),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,oxygen-regulated invasion protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15787,PHI:10091,UniProt,D0ZV07,GenBank,ACY89883,,,14028S,STM14_RS15390 (orgA),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,oxygen-regulated invasion protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15788,PHI:10092,UniProt,A0A0F6B5T9,GenBank,ACY89884,,,14028S,STM14_RS15395 (prgK),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system inner membrane ring lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15789,PHI:10093,UniProt,A0A0F6B5U0,GenBank,ACY89885,,,14028S,STM14_RS15400 (prgJ),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10094; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system inner rod protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15790,PHI:10094,UniProt,A0A0F6B5U1,GenBank,ACY89886,,,14028S,STM14_RS15405 (prgI),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10095; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system needle complex protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15791,PHI:10095,UniProt,A0A0F6B5U2,GenBank,ACY89887,,,14028S,STM14_RS15410 (prgH),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10096; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system inner membrane ring protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15792,PHI:10096,UniProt,A0A0F6B5U3,GenBank,ACY89888,,,14028S,STM14_RS15415 (hilD),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10097; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15793,PHI:10097,UniProt,A0A0F6B5U4,GenBank,ACY89889,,,14028S,STM14_RS15420 (hilA),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10098,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15794,PHI:10098,UniProt,A0A0F6B5U5,GenBank,ACY89890,,,14028S,STM14_RS15425 (iagB),,,,,,PHI:10052; PHI:10053; PHI:10054; PHI:10055; PHI:10056; PHI:10057; PHI:10058; PHI:10059; PHI:10060; PHI:10061; PHI:10062; PHI:10063; PHI:10064; PHI:10065; PHI:10066; PHI:10067; PHI:10068; PHI:10069; PHI:10070; PHI:10071; PHI:10072; PHI:10073; PHI:10074; PHI:10075; PHI:10076; PHI:10077; PHI:10078; PHI:10079; PHI:10080; PHI:10081; PHI:10082; PHI:10083; PHI:10084; PHI:10085; PHI:10086; PHI:10087; PHI:10088; PHI:10089; PHI:10090; PHI:10091; PHI:10092; PHI:10093; PHI:10094; PHI:10095; PHI:10096; PHI:10097,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,SPI-1 type III secretion system invasion protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15795,PHI:10099,UniProt,A0A0F6B0W4,GenBank,ACY88142,,,14028S,STM14_RS07705 (sufB),,,,,,PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,Fe-S cluster assembly protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15796,PHI:10100,UniProt,A0A0F6B0W5,GenBank,ACY88143,,,14028S,STM14_RS07710 (sufC),,,,,,PHI:10099; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,Fe-S cluster assembly ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15797,PHI:10101,UniProt,A0A0F6B0W6,GenBank,ACY88144,,,14028S,STM14_RS07715 (sufD),,,,,,PHI:10099; PHI:10100; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,Fe-S cluster assembly protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15798,PHI:10102,UniProt,A0A0F6B0W7,GenBank,ACY88145,,,14028S,STM14_RS07720 (sufS),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,cysteine desulfurase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15799,PHI:10103,UniProt,A0A0F6B0W8,GenBank,ACY88146,,,14028S,STM14_RS07725 (ynhA/sufE),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,cysteine desulfuration protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15800,PHI:10104,UniProt,A0A0F6B0W9,GenBank,ACY88147,,,14028S,STM14_RS07730 (ynhG),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,"murein L,D-transpeptidase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15801,PHI:10105,UniProt,A0A0F6B0X0,GenBank,ACY88148,,,14028S,STM14_RS07735 (lppB),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15802,PHI:10106,UniProt,A0A0F6B0X1,GenBank,ACY88149,,,14028S,STM14_RS07740 (lpp),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,murein lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15803,PHI:10107,UniProt,A0A0F6B0X2,GenBank,ACY88150,,,14028S,STM14_RS07745 (pykF),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,pyruvate kinase I,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15804,PHI:10108,UniProt,no data found,GenBank,,,,,STM14_RS24765,,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15805,PHI:10109,UniProt,A0A0F6B0X3,GenBank,ACY88151,,,14028S,STM14_RS07750 (orf48),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,APC family permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15806,PHI:10110,UniProt,A0A0F6B0X4,GenBank,ACY88152,,,14028S,STM14_RS07755 (orf32),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,alpha/beta fold hydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15807,PHI:10111,UniProt,A0A0F6B0X5,GenBank,ACY88153,,,14028S,STM14_RS07760 (orf245),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15808,PHI:10112,UniProt,A0A0F6B0X6,GenBank,ACY88154,,,14028S,STM14_RS07765 (orf408),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,DeoR family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15809,PHI:10113,UniProt,A0A0F6B0X7,GenBank,ACY88155,,,14028S,STM14_RS07770 (ttrA),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,tetrathionate reductase subunit A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15810,PHI:10114,UniProt,A0A0F6B0X8,GenBank,ACY88156,,,14028S,STM14_RS07775 (ttrC),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,tetrathionate reductase subunit C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15811,PHI:10115,UniProt,A0A0F6B0X9,GenBank,ACY88157,,,14028S,STM14_RS07780 (ttrB),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,tetrathionate reductase subunit B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15812,PHI:10116,UniProt,A0A0F6B0Y0,GenBank,ACY88158,,,14028S,STM14_RS07785 (ttrS),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,two-component system sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15813,PHI:10117,UniProt,Q7CQM8,GenBank,,,,,STM14_RS07790 (ttrR),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,two-component system response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15814,PHI:10118,UniProt,A0A0F6B0Y2,GenBank,ACY88160,,,14028S,STM14_RS07795 (orf70),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15815,PHI:10119,UniProt,A0A0F6B0Y3,GenBank,ACY88161,,,14028S,STM14_RS07800 (orf319),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,DUF523 and DUF1722 domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15816,PHI:10120,UniProt,A0A0F6B0Y4,GenBank,ACY88162,,,14028S,STM14_RS07805 (orf242),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,MerR family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15817,PHI:10121,UniProt,A0A0F6B0Y6,GenBank,ACY88164,,,14028S,STM14_RS07810 (ssrB),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,two component system response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15818,PHI:10122,UniProt,A0A0F6B0Y7,GenBank,ACY88165,,,14028S,STM14_RS07815 (ssrA),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hybrid sensor histidine kinase/response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15819,PHI:10123,UniProt,D0ZWR8,GenBank,ACY88166,,,14028S,STM14_RS07820 (ssaB/spiC),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,pathogenicity island chaperone protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15820,PHI:10124,UniProt,D0ZWR9,GenBank,ACY88167,,,14028S,STM14_RS07825 (ssaC/spiA),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,EscC/YscC/HrcC family type III secretion system outer membrane ring protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15821,PHI:10125,UniProt,A0A0F6B0Y8,GenBank,ACY88168,,,14028S,STM14_RS07830 (ssaD),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,EscD/YscD/HrpQ family type III secretion system inner membrane ring protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15822,PHI:10126,UniProt,A0A0F6B0Y9,GenBank,ACY88169,,,14028S,STM14_RS07835 (ssaE),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,EscE/YscE/SsaE family type III secretion system needle protein co-chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15823,PHI:10127,UniProt,A0A0F6B0Z1,GenBank,ACY88171,,,14028S,STM14_RS07840 (sseA),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,SPI-2 type III secretion system chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15824,PHI:10128,UniProt,A0A0F6B0Z2,GenBank,ACY88172,,,14028S,STM14_RS07845 (sseB),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,pathogenicity island 2 effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15825,PHI:10129,UniProt,A0A0F6B0Z3,GenBank,ACY88173,,,14028S,STM14_RS07850 (sscA),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,CesD/SycD/LcrH family type III secretion system chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15826,PHI:10130,UniProt,A0A0F6B0Z4,GenBank,ACY88174,,,14028S,STM14_RS07855 (sseC),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,pathogenicity island 2 effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15827,PHI:10131,UniProt,A0A0F6B0Z5,GenBank,ACY88175,,,14028S,STM14_RS07860 (sseD),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,pathogenicity island 2 effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15828,PHI:10132,UniProt,A0A0F6B0Z6,GenBank,ACY88176,,,14028S,STM14_RS07865 (sseE),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,pathogenicity island 2 effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15829,PHI:10133,UniProt,A0A0F6B0Z7,GenBank,ACY88177,,,14028S,STM14_RS07870 (sscB),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,CesD/SycD/LcrH family type III secretion system chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15830,PHI:10134,UniProt,A0A0F6B0Z8,GenBank,ACY88178,,,14028S,STM14_RS07875 (sseF),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,pathogenicity island 2 effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15831,PHI:10135,UniProt,A0A0F6B0Z9,GenBank,ACY88179,,,14028S,STM14_RS07880 (sseG),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,pathogenicity island 2 effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15832,PHI:10136,UniProt,A0A0F6B100,GenBank,ACY88180,,,14028S,STM14_RS07885 (ssaG),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system needle protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15833,PHI:10137,UniProt,A0A0F6B101,GenBank,,,,,STM14_RS07890 (ssaH),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system needle protein co-chaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15834,PHI:10138,UniProt,A0A0F6B102,GenBank,ACY88182,,,14028S,STM14_RS07895 (ssaI),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system inner rod protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15835,PHI:10139,UniProt,D0ZWT5,GenBank,ACY88183,,,14028S,STM14_RS07900 (ssaJ),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion inner membrane ring protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15836,PHI:10140,UniProt,A0A0F6B103,GenBank,ACY88184,,,14028S,STM14_RS07905,,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15837,PHI:10141,UniProt,A0A0F6B104,GenBank,ACY88185,,,14028S,STM14_RS07910 (ssaK),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15838,PHI:10142,UniProt,A0A0F6B105,GenBank,ACY88186,,,14028S,STM14_RS07915 (ssaL),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15839,PHI:10143,UniProt,A0A0F6B106,GenBank,ACY88187,,,14028S,STM14_RS07920 (ssaM),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15840,PHI:10144,UniProt,D0ZWU0,GenBank,ACY88188,,,14028S,STM14_RS07925 (ssaV),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system export apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15841,PHI:10145,UniProt,A0A0F6B107,GenBank,ACY88189,,,14028S,STM14_RS07930 (ssaN),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15842,PHI:10146,UniProt,A0A0F6B108,GenBank,ACY88190,,,14028S,STM14_RS07935 (ssaO),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15843,PHI:10147,UniProt,A0A0F6B109,GenBank,ACY88191,,,14028S,STM14_RS07940 (ssaP),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10148; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15844,PHI:10148,UniProt,A0A0F6B110,GenBank,ACY88192,,,14028S,STM14_RS07945 (ssaQ),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10149; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,secretion system apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15845,PHI:10149,UniProt,A0A0F6B111,GenBank,ACY88193,,,14028S,STM14_RS07950 (ssaR),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10150; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system export apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15846,PHI:10150,UniProt,A0A0F6B112,GenBank,ACY88194,,,14028S,STM14_RS07955 (ssaS),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10151; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system export apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15847,PHI:10151,UniProt,A0A0F6B113,GenBank,ACY88195,,,14028S,STM14_RS07960 (ssaT),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10152,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system export apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15848,PHI:10152,UniProt,A0A0F6B114,GenBank,ACY88196,,,14028S,STM14_RS07965 (ssaU),,,,,,PHI:10099; PHI:10100; PHI:10101; PHI:10102; PHI:10103; PHI:10104; PHI:10105; PHI:10106; PHI:10107; PHI:10108; PHI:10109; PHI:10110; PHI:10111; PHI:10112; PHI:10113; PHI:10114; PHI:10115; PHI:10116; PHI:10117; PHI:10118; PHI:10119; PHI:10120; PHI:10121; PHI:10122; PHI:10123; PHI:10124; PHI:10125; PHI:10126; PHI:10127; PHI:10128; PHI:10129; PHI:10130; PHI:10131; PHI:10132; PHI:10133; PHI:10134; PHI:10135; PHI:10136; PHI:10137; PHI:10138; PHI:10139; PHI:10140; PHI:10141; PHI:10142; PHI:10143; PHI:10144; PHI:10145; PHI:10146; PHI:10147; PHI:10148; PHI:10149; PHI:10150; PHI:10151,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),var. crispa cv. Salinas,,,leaf,type III secretion system export apparatus switch protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32038592,PubMed,10.3389/fmicb.2020.00006,Front Microbiol. 2020 Jan 24;11:6,melotto@ucdavis.edu,"The growth of mutants lacking SPI-2, but not mutants lacking SPI-1, was significantly impaired in the leaf apoplastic wash fluid (AWF) suggesting that the STm persistence in the apoplast may be linked to nutrient acquisition capabilities or overall bacterial fitness in this niche, which are dependent on the gene(s) deleted in the mutant strain lacking SPI-2.",J Montano 2020,2020,101 genes,Montano-2020-Salmonella enterica Serovar Typhi,BATCH_099C,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15849,PHI:10153,UniProt,A0A0Z8IRD4,GenBank,CYV40285,,,LSS69,atlA,,,,,,,1307,Streptococcus suis,,CZ130302,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung; blood; kidney,putative autolysin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31213278,PubMed,10.1016/j.vetmic.2019.05.020,Vet Microbiol. 2019 Jul;234:92-100,yaohch@njau.edu.cn,"AtlASS autolysin modulated bacterial chain length, and contributed to the full virulence of SS during infection.",Y Zhang 2019,2019,1 gene,Zhang-2019-A novel autolysin AtlASS mediates b,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15850,PHI:10153,UniProt,A0A0Z8IRD4,GenBank,CYV40285,,,LSS69,atlA,,,,,,,1307,Streptococcus suis,,CZ130302,meningitis; septicemia; arthritis; pneumonia (pig),primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,putative autolysin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31213278,PubMed,10.1016/j.vetmic.2019.05.020,Vet Microbiol. 2019 Jul;234:92-100,yaohch@njau.edu.cn,"AtlASS autolysin modulated bacterial chain length, and contributed to the full virulence of SS during infection.",Y Zhang 2019,2019,1 gene,Zhang-2019-A novel autolysin AtlASS mediates b,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15851,PHI:10154,UniProt,B2HE54,GenBank,ACC41334,,,M,MMAR_2894,,,,,,,1781,Mycobacterium marinum,1348799,M,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,PE family protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30833360,PubMed,10.1128/JB.00760-18,J Bacteriol. 2019 Jun 21;201(14),pchampio@nd.edu,MMAR_2894 is dispensable for cytolysis of RAW 264.7 cells.,R E Bosserman 2019,2019,2 genes,Bosserman-2019-A new ESX-1 substrate in M. mar,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15852,PHI:10154,UniProt,A0A3E2MUT9,GenBank,RFZ40190,,,Davis1,eccCb1,,,,,,,1781,Mycobacterium marinum,1348799,M,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,ESX-1 secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30833360,PubMed,10.1128/JB.00760-18,J Bacteriol. 2019 Jun 21;201(14),pchampio@nd.edu,MMAR_2894 is dispensable for cytolysis of RAW 264.7 cells.,R E Bosserman 2019,2019,2 genes,Bosserman-2019-A new ESX-1 substrate in M. mar,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15853,PHI:10155,UniProt,B2HE54,GenBank,ACC41334,,,M,MMAR_2894,,,,,,,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,PE family protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30833360,PubMed,10.1128/JB.00760-18,J Bacteriol. 2019 Jun 21;201(14),pchampio@nd.edu,MMAR_2894 gene was required for the optimal secretion of ESX-1 substrates in vitro and for hemolysis.,R E Bosserman 2019,2019,2 genes,Bosserman-2019-A new ESX-1 substrate in M. mar,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15854,PHI:10156,UniProt,A1KRA2,GenBank,CAM09378,,,FAM18,cssA,,,,,,,487,Neisseria meningitidis,,93/4286,meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,N-acetylglucosamine-6-phosphate 2-epimerase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30718288,PubMed,10.1128/IAI.00688-18,Infect Immun. 2019 Mar 25;87(4),psalvato@unina.it,Mice infected with the cssA-defective mutant showed reduced intracerebral hemorrhages.,R Colicchio 2019,2019,1 gene,Colicchio-2019-Virulence traits of serogroup C,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15855,PHI:10157,UniProt,A0A0H3MCG4,GenBank,CAP03507,,,434/Bu,tmeA (CTL0063),,,,,,,813,Chlamydia trachomatis,,L2,urinary tract infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full; gene complementation,,,YVS,28970272,PubMed,10.1128/IAI.00640-17,Infect Immun. 2017 Nov 17;85(12),Ken.fields@uky.edu,Disruption of either tmeA or ctl0065 negatively impacts the ability of chlamydiae to sustain infection.,M J McKuen 2017,2017,3 genes,McKuen-2017-FRAEM reveals a role for C. tracho,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15856,PHI:10158,UniProt,A0A0H3MJS5,GenBank,CAP03508,,,434/Bu,tmeB (CTL0064),,,,,,,813,Chlamydia trachomatis,,L2,urinary tract infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,28970272,PubMed,10.1128/IAI.00640-17,Infect Immun. 2017 Nov 17;85(12),Ken.fields@uky.edu,TmeB-deficient strain showed no decrease in infectivity.,M J McKuen 2017,2017,3 genes,McKuen-2017-FRAEM reveals a role for C. tracho,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15857,PHI:10157,UniProt,A0A0H3MCG4,GenBank,CAP03507,,,434/Bu,tmeA (CTL0063),,,,,,,813,Chlamydia trachomatis,,L2,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),MEF,,,embryonic fibroblast cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full; gene complementation,,,YVS,28970272,PubMed,10.1128/IAI.00640-17,Infect Immun. 2017 Nov 17;85(12),Ken.fields@uky.edu,Disruption of either tmeA or ctl0065 negatively impacts the ability of chlamydiae to sustain infection.,M J McKuen 2017,2017,3 genes,McKuen-2017-FRAEM reveals a role for C. tracho,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15858,PHI:10158,UniProt,A0A0H3MCG4,GenBank,CAP03507,,,434/Bu,tmeA (CTL0063),,,,,,,813,Chlamydia trachomatis,,L2,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full; gene complementation,,,YVS,28970272,PubMed,10.1128/IAI.00640-17,Infect Immun. 2017 Nov 17;85(12),Ken.fields@uky.edu,Disruption of either tmeA or ctl0065 negatively impacts the ability of chlamydiae to sustain infection.,M J McKuen 2017,2017,3 genes,McKuen-2017-FRAEM reveals a role for C. tracho,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15859,PHI:10159,UniProt,A0A0H3MB65,GenBank,CAP03509,,,434/Bu,CTL0065,,,,,,,813,Chlamydia trachomatis,,L2,urinary tract infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,conserved hypothetical protein,,,,reduced virulence,,,,,,,,reduced,,no,cytochalasin D,cytochalasin D: CHEBI:529996,,,,,gene deletion: full,,,YVS,28970272,PubMed,10.1128/IAI.00640-17,Infect Immun. 2017 Nov 17;85(12),Ken.fields@uky.edu,Disruption of either tmeA or ctl0065 negatively impacts the ability of chlamydiae to sustain infection.,M J McKuen 2017,2017,3 genes,McKuen-2017-FRAEM reveals a role for C. tracho,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15860,PHI:10160,UniProt,A0A158LZB4,GenBank,ENV27259,,,NIPH 190,ksgA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,skin infection; soft tissue infection; urinary tract infection; meningitis; wound infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,16S rRNA methyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,kanamycin; gentamicin; paromomycin; tobramycin; neomycin; amikacin; kasugamycin,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; paromomycin: CHEBI:7934; tobramycin: CHEBI:28864; neomycin: CHEBI:7507; amikacin: CHEBI:2637; kasugamycin: CHEBI:81419,,,,,gene deletion: full; gene complementation,,,YVS,30082289,PubMed,10.1128/AAC.00853-18,Antimicrob Agents Chemother. 2018 Sep 24;62(10),JunZheng@umac.mo,KsgA was important for bacterial survival both in the presence of aminoglycoside and inside the host.,J Zou 2018,2018,1 gene,Zou-2018-Studies on Aminoglycoside Susceptibil,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15861,PHI:10162,UniProt,Q2T7Q1,GenBank,ABC35933,,,ATCC 700388,ohrR (BTH_II0598),chromosome II,,,,,,57975,Burkholderia thailandensis,271848,ATCC 700388D-5,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,"transcription factor, organic hydroperoxide reductase regulator",,,,reduced virulence,,,,,,,,,,no,cumene hydroperoxide; H2O2; NaOCl,cumene hydroperoxide: CHEBI:78673; H2O2: CHEBI:16240; sodium hypochlorite (NaOCl): CHEBI:32146,,,,,gene disruption; gene complementation,,,YVS,29967095,PubMed,10.1128/IAI.00322-18,Infect Immun. 2018 Aug 22;86(9),agrove@lsu.edu,"While Δohr cells were more virulent in a Caenorhabditis elegans model of infection, ΔohrR cells were less so.",A Pande 2018,2018,2 genes,Pande-2018-Gene regulation by redox-sensitive,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15862,PHI:10163,UniProt,Q2T7Q2,GenBank,ABC35439,,,ATCC 700388,ohr (BTH_II0597),chromosome II,,,,,,57975,Burkholderia thailandensis,271848,ATCC 700388D-5,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,organic hydroperoxide resistance protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,cumene hydroperoxide; H2O2; NaOCl,cumene hydroperoxide: CHEBI:78673; H2O2: CHEBI:16240; sodium hypochlorite (NaOCl): CHEBI:32146,,,,,gene disruption; gene complementation,,,YVS,29967095,PubMed,10.1128/IAI.00322-18,Infect Immun. 2018 Aug 22;86(9),agrove@lsu.edu,"While Δohr cells were more virulent in a Caenorhabditis elegans model of infection, ΔohrR cells were less so.",A Pande 2018,2018,2 genes,Pande-2018-Gene regulation by redox-sensitive,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15863,PHI:10164,UniProt,A0A2K1SXK6,GenBank,PNS44263,,,NJAU-TF-202,PnuC,,,,,,,1307,Streptococcus suis,,ZY05719,septicemia; meningitis; arthritis; endocarditis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,nicotinamide mononucleotide transporter,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,29519516,PubMed,10.1016/j.vetmic.2018.02.013,Vet Microbiol. 2018 Mar;216:198-206,vszw@njau.edu.cn,PnuC was involved in the oxidative stress tolerance and virulence of S. suis 2 during infection.,Q Li 2018,2018,1 gene,Li-2018-Characterization and functional analys,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15864,PHI:10164,UniProt,A0A2K1SXK6,GenBank,PNS44263,,,NJAU-TF-202,PnuC,,,,,,,1307,Streptococcus suis,,ZY05719,septicemia; meningitis; arthritis; endocarditis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,nicotinamide mononucleotide transporter,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,29519516,PubMed,10.1016/j.vetmic.2018.02.013,Vet Microbiol. 2018 Mar;216:198-206,vszw@njau.edu.cn,PnuC was involved in the oxidative stress tolerance and virulence of S. suis 2 during infection.,Q Li 2018,2018,1 gene,Li-2018-Characterization and functional analys,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15865,PHI:10164,UniProt,A0A2K1SXK6,GenBank,PNS44263,,,NJAU-TF-202,PnuC,,,,,,,1307,Streptococcus suis,,ZY05719,septicemia; meningitis; arthritis; endocarditis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,nicotinamide mononucleotide transporter,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,29519516,PubMed,10.1016/j.vetmic.2018.02.013,Vet Microbiol. 2018 Mar;216:198-206,vszw@njau.edu.cn,PnuC did not play a role in the bacterial adherence and invasion to host cells.,Q Li 2018,2018,1 gene,Li-2018-Characterization and functional analys,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15866,PHI:10164,UniProt,A0A2K1SXK6,GenBank,PNS44263,,,NJAU-TF-202,PnuC,,,,,,,1307,Streptococcus suis,,ZY05719,septicemia; meningitis; arthritis; endocarditis,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,nicotinamide mononucleotide transporter,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,29519516,PubMed,10.1016/j.vetmic.2018.02.013,Vet Microbiol. 2018 Mar;216:198-206,vszw@njau.edu.cn,PnuC did not play a role in the bacterial adherence and invasion to host cells.,Q Li 2018,2018,1 gene,Li-2018-Characterization and functional analys,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15867,PHI:10165,UniProt,Q48S41,GenBank,AAX72469,,,MGAS6180,RocA,,,,,,,1314,Streptococcus pyogenes,,serotype M28 strain MGAS28426,pharyngitis; necrotizing fasciitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,limb,sensory transduction protein kinase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30126898,PubMed,10.1128/IAI.00467-18,Infect Immun. 2018 Oct 25;86(11),rjolsen@houstonmethodist.org,RocA inactivation significantly increased GAS virulence in a mouse model of necrotizing myositis.,P E Bernard 2018,2018,1 gene,Bernard-2018-RocA has serotype-specific gene r,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15868,PHI:10166,UniProt,S8FDJ8,GenBank,XP_002369451,,,,HSD (TGME49_253960),,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,estradiol regulatory factor-hydroxysteroid dehydrogenase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28887145,PubMed,10.1016/j.jsbmb.2017.09.001,J Steroid Biochem Mol Biol. 2017 Nov;174:176-182,qunliu@cau.edu.cn,Tg-HSD -overexpressing parasites showed significantly enhanced pathogenicity and up-regulation of estradiol levels in mice.,X Zhang 2017,2017,1 gene,Zhang-2017-Role of an estradiol regulatory fac,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15869,PHI:10167,UniProt,O51113,GenBank,AAC66471,,,B31,badP (bb0086),,,,,,,139,Borreliella burgdorferi,,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,abdomen; spleen; bladder; heart; deep inguinal lymph node; tibiotarsal joint; macrophage,host adaptation regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29685985,PubMed,10.1128/IAI.00057-18,Infect Immun. 2018 Jun 21;86(7),j.seshu@utsa.edu,The badP mutant was unable to colonize C3H/HeN mice at all time points postinfection.,T C Smith 2018,2018,1 gene,Smith-2018-Borrelia host adaptation Protein (B,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15870,PHI:10168,UniProt,Q2FV90,GenBank,ABD31845,,,NCTC 8325,fphB (SAOUHSC_02844),,,,,,,1280,Staphylococcus aureus,426430,Newman,infection,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,liver; heart,abhydrolase_3 domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29769740,PubMed,10.1038/s41589-018-0060-1,Nat Chem Biol. 2018 Jun;14(6):609-617,mbogyo@stanford.edu,"Mice infected with the fphB transposon mutant strain had ~10- to 100-fold lower bacterial loads than the WT strain in liver and heart tissues, but equal colony-forming unit (CFU) numbers in the kidneys.",C S Lentz 2018,2018,2 genes,Lentz-2018-Identification of a S. aureus virul,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15871,PHI:10168,UniProt,Q2FV90,GenBank,ABD31845,,,NCTC 8325,fphB (SAOUHSC_02844),,,,,,,1280,Staphylococcus aureus,426430,Newman,infection,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,kidney,abhydrolase_3 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,29769740,PubMed,10.1038/s41589-018-0060-1,Nat Chem Biol. 2018 Jun;14(6):609-617,mbogyo@stanford.edu,"Mice infected with the fphB transposon mutant strain had ~10- to 100-fold lower bacterial loads than the WT strain in liver and heart tissues, but equal colony-forming unit (CFU) numbers in the kidneys.",C S Lentz 2018,2018,2 genes,Lentz-2018-Identification of a S. aureus virul,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15872,PHI:10169,UniProt,no data found,GenBank,,,,,fphE,,,,,,,1280,Staphylococcus aureus,426430,Newman,infection,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,liver,abhydrolase_3 domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29769740,PubMed,10.1038/s41589-018-0060-1,Nat Chem Biol. 2018 Jun;14(6):609-617,mbogyo@stanford.edu,"Infection with the fphE transposon mutant resulted in only a small, though statistically significant, reduction of bacterial loads in the liver, and no reduction in the hearts or kidneys of infected mice.",C S Lentz 2018,2018,2 genes,Lentz-2018-Identification of a S. aureus virul,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15873,PHI:10169,UniProt,no data found,GenBank,,,,,fphE,,,,,,,1280,Staphylococcus aureus,426430,Newman,infection,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,kidney; heart,abhydrolase_3 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29769740,PubMed,10.1038/s41589-018-0060-1,Nat Chem Biol. 2018 Jun;14(6):609-617,mbogyo@stanford.edu,"Infection with the fphE transposon mutant resulted in only a small, though statistically significant, reduction of bacterial loads in the liver, and no reduction in the hearts or kidneys of infected mice.",C S Lentz 2018,2018,2 genes,Lentz-2018-Identification of a S. aureus virul,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15874,PHI:10170,UniProt,A0A1B2VWC1,GenBank,AOD41683,,,SC1516,tolC1,,,,,,,715,Actinobacillus pleuropneumoniae,,SC1516,porcine contagious pleuropneumoniae,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,KCl; H2O2,KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31212036,PubMed,10.1016/j.micpath.2019.103596,Microb Pathog. 2019 Sep;134:103596,xintian3211@126.com,"The tolC1 mutant was hypersensitive to oxidative, osmotic and acid challenges by in vitro stress assays.",Y Li 2019,2019,1 gene,Li-2019-A requirement of TolC1 for effective s,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15875,PHI:10171,UniProt,Q7MBB2,GenBank,AAP56827,,,R,groEL,,,,,,,2096,Mycoplasmoides gallisepticum,233150,R,airsacculitis,primates,9606,Homo sapiens (related: human),HEK293T cell line,,,HEK-293T cell,60 kDa chaperonin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31235640,PubMed,10.1128/IAI.00248-19,Infect Immun. 2019 Aug 21;87(9),wanggang@caas.cn,"GroEL induced apoptosis in host cells by interacting with annexin A2, a novel virulence mechanism in Mycoplasma gallisepticum. Host gene alteration data available for annexin A2.",Y Yu 2019,2019,1 gene,Yu-2019-GroEL protein (Heat shock protein 60),BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15876,PHI:10171,UniProt,Q7MBB2,GenBank,AAP56827,,,R,groEL,,,,,,,2096,Mycoplasmoides gallisepticum,233150,R,airsacculitis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryo fibroblast cell line; blood,60 kDa chaperonin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31235640,PubMed,10.1128/IAI.00248-19,Infect Immun. 2019 Aug 21;87(9),wanggang@caas.cn,"GroEL induced apoptosis in host cells by interacting with annexin A2, a novel virulence mechanism in Mycoplasma gallisepticum. Host gene alteration data available for annexin A2.",Y Yu 2019,2019,1 gene,Yu-2019-GroEL protein (Heat shock protein 60),BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15877,PHI:10171,UniProt,Q7MBB2,GenBank,AAP56827,,,R,groEL,,,,,,,2096,Mycoplasmoides gallisepticum,233150,R,airsacculitis,birds,9031,Gallus gallus (related: chicken),PBMCs,,,peripheral blood mononuclear cell,60 kDa chaperonin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,31235640,PubMed,10.1128/IAI.00248-19,Infect Immun. 2019 Aug 21;87(9),wanggang@caas.cn,"GroEL induced apoptosis in host cells by interacting with annexin A2, a novel virulence mechanism in Mycoplasma gallisepticum. Host gene alteration data available for annexin A2.",Y Yu 2019,2019,1 gene,Yu-2019-GroEL protein (Heat shock protein 60),BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15878,PHI:10172,UniProt,A4VXJ5,GenBank,ABP90834,,,05ZYH33,oppA (05ssu1868),,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,oligopeptide permease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,29614370,PubMed,10.1016/j.micpath.2018.03.061,Microb Pathog. 2018 May;118:322-329,panxiuzhen_2004@163.com,Mouse infection experiment showed that inactivation of oppA greatly attenuated the high pathogenicity of S. suis 2.,F Zheng 2018,2018,1 gene,Zheng-2018-Identification of oligopeptide-bind,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15879,PHI:10172,UniProt,A4VXJ5,GenBank,ABP90834,,,05ZYH33,oppA (05ssu1868),,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,oligopeptide permease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,29614370,PubMed,10.1016/j.micpath.2018.03.061,Microb Pathog. 2018 May;118:322-329,panxiuzhen_2004@163.com,Adherence of the ΔoppA strain to human epithelial cells was greatly reduced comparing to the wild strain.,F Zheng 2018,2018,1 gene,Zheng-2018-Identification of oligopeptide-bind,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15880,PHI:10173,UniProt,Q9HXB5,GenBank,AE004807_4,,,PAO1,PA3898,,PA3898::Tn,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,flies,7227,Drosophila melanogaster (related: fruit fly),Canton-S,,,,AraC family transcriptional regulator,,,phenazine biosynthesis,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30297364,PubMed,10.1128/AAC.01459-18,Antimicrob Agents Chemother. 2018 Nov 26;62(12),tongh@hawaii.edu,A PA3898 mutant was significantly reduced in ability of P. aeruginosa to produce biofilm in vitro.,Y Heacock-Kang 2018,2018,1 gene,"Heacock-Kang-2018-Two regulators, PA3898 and P",BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15881,PHI:10173,UniProt,Q9HXB5,GenBank,AE004807_4,,,PAO1,PA3898,,PA3898::Tn,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,AraC family transcriptional regulator,,,phenazine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,30297364,PubMed,10.1128/AAC.01459-18,Antimicrob Agents Chemother. 2018 Nov 26;62(12),tongh@hawaii.edu,A PA3898 mutant was significantly reduced in ability of P. aeruginosa to produce biofilm in vitro.,Y Heacock-Kang 2018,2018,1 gene,"Heacock-Kang-2018-Two regulators, PA3898 and P",BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15882,PHI:10174,UniProt,P40719,GenBank,AAC76062,,,K-12,QseC,,,,,,,562,Escherichia coli,1048254,C227-11,hemolytic uremic syndrome; colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,gut,histidine kinase sensor,,,,unaffected pathogenicity,,,,,,,,,,no,N-phenyl-4-[[(phenylamino)thioxomethyl]amino]-benzenesulfonamide (LED209),N-phenyl-4-[[(phenylamino)thioxomethyl]amino]-benzenesulfonamide (LED209) cas no.: CAS:245342-14-7,,,,,gene mutation; gene complementation,,,YVS,31235511,PubMed,10.1128/JB.00203-19,J Bacteriol. 2019 Aug 8;201(17),cg.moreira@unesp.br,The blocking of QseC of EAEC C227-11 (Stx) strain by N-phenyl-4-{[(phenylamino) thioxomethyl]amino}-benzenesulfonamide (also known as LED209) invivo demonstrated a lower efficiency of colonization.,T R Machado Ribeiro 2019,2019,1 gene,Ribeiro-2019-QseC signaling in the outbreak O1,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15883,PHI:10174,UniProt,P40719,GenBank,AAC76062,,,K-12,QseC,,,,,,,562,Escherichia coli,1048254,C227-11,hemolytic uremic syndrome; colitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,histidine kinase sensor,,,,unaffected pathogenicity,,,,,,,,,,no,N-phenyl-4-[[(phenylamino)thioxomethyl]amino]-benzenesulfonamide (LED209),N-phenyl-4-[[(phenylamino)thioxomethyl]amino]-benzenesulfonamide (LED209) cas no.: CAS:245342-14-7,,,,,gene mutation; gene complementation,,,YVS,31235511,PubMed,10.1128/JB.00203-19,J Bacteriol. 2019 Aug 8;201(17),cg.moreira@unesp.br,No significant difference was demonstrated for the ::qseC mutant in adhesion ability to HeLa cells.,T R Machado Ribeiro 2019,2019,1 gene,Ribeiro-2019-QseC signaling in the outbreak O1,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15884,PHI:10175,UniProt,Q9RL81,GenBank,AUS74922,,,MRSA107,Stp1,,,,,,,1280,Staphylococcus aureus,426430,Newman,endocarditis; pneumonia; septicemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver,protein-serine/threonine phosphatase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27499528,PubMed,10.1016/j.chembiol.2016.06.014,Cell Chem Biol. 2016 Aug 18;23(8):1002-13,lizg@pkusz.edu.cn,"ATA did not affect in vitro growth of Staphylococcus aureus, while simultaneously attenuating staphylococcal virulence in mice.",W Zheng 2016,2016,1 gene,Zheng-2016-Structure-Based Identification of a,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15885,PHI:10175,UniProt,Q9RL81,GenBank,AUS74922,,,MRSA107,Stp1,,,,,,,1280,Staphylococcus aureus,426430,Newman,endocarditis; pneumonia; septicemia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,protein-serine/threonine phosphatase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27499528,PubMed,10.1016/j.chembiol.2016.06.014,Cell Chem Biol. 2016 Aug 18;23(8):1002-13,lizg@pkusz.edu.cn,ΔStp1 strain was not affected by ATA but did display reduced hemolysis compared with the WT strain.,W Zheng 2016,2016,1 gene,Zheng-2016-Structure-Based Identification of a,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15886,PHI:10176,UniProt,A0A0H3NXZ9,GenBank,CCG27797,,,SL1344,yshB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; macrophage,conserved sORF,,,,reduced virulence,,,,,,,,,,no,streptomycin; kanamycin,streptomycin: CHEBI:17076; kanamycin: CHEBI:6104,,,,,gene disruption; gene complementation,,,YVS,31182500,PubMed,10.1128/JB.00314-19,J Bacteriol. 2019 Aug 8;201(17),zhoud@purdue.edu,Lack of YshB resulted in reduced bacterial survival within the macrophages and led to reduced virulence in a mouse model of infection.,R Bomjan 2019,2019,1 gene,Bomjan-2019-YshB promotes intracellular replic,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15887,PHI:10176,UniProt,A0A0H3NXZ9,GenBank,CCG27797,,,SL1344,yshB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,conserved sORF,,,,reduced virulence,,,,,,,,,,no,streptomycin; kanamycin,streptomycin: CHEBI:17076; kanamycin: CHEBI:6104,,,,,gene disruption; gene complementation,,,YVS,31182500,PubMed,10.1128/JB.00314-19,J Bacteriol. 2019 Aug 8;201(17),zhoud@purdue.edu,Lack of YshB resulted in reduced bacterial survival within the macrophages and led to reduced virulence in a mouse model of infection.,R Bomjan 2019,2019,1 gene,Bomjan-2019-YshB promotes intracellular replic,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15888,PHI:10177,UniProt,P75829,GenBank,AAC73964,,,K-12,ybjX,,,,,,,562,Escherichia coli,,AE17,colibacillosis,birds,9031,Gallus gallus (related: chicken),Roman hens,,,,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,polymyxin B,polymixin B: CHEBI:8310,,,,,gene mutation; gene complementation,,,YVS,29517278,PubMed,10.1080/03079457.2018.1448053,Avian Pathol. 2018 Jun;47(3):294-299,qkz@ahau.edu.cn,"The results indicated that mutation of ybjX may attenuate APEC pathogenicity, not only by affecting bacterial adhesion and invasion, but also via reducing resistance to avian beta-defensin by increasing outer membrane permeabilization of bacteria.",X Song 2018,2018,1 gene,Song-2018-The role of the outer membrane prote,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15889,PHI:10177,UniProt,P75829,GenBank,AAC73964,,,K-12,ybjX,,,,,,,562,Escherichia coli,,AE17,colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryo fibroblast cell line,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,polymyxin B,polymixin B: CHEBI:8310,,,,,gene mutation; gene complementation,,,YVS,29517278,PubMed,10.1080/03079457.2018.1448053,Avian Pathol. 2018 Jun;47(3):294-299,qkz@ahau.edu.cn,The mutant strain displayed significantly reduced adherence to and invasion of chicken embryo fibroblast cell line (DF-1) cells.,X Song 2018,2018,1 gene,Song-2018-The role of the outer membrane prote,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15890,PHI:10178,UniProt,A0A0K0GQW7,GenBank,AJQ85091,,,PXO86,rocF (PXO_RS22625),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,arginase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31290730,PubMed,10.1094/PHYTO-02-19-0058-R,Phytopathology. 2019 Nov;109(11):1869-1877,fqliu20011@sina.com,"The rocF deletion mutant strain showed elevated sensitivity to hydrogen peroxide, reduced extracellular polysaccharide (EPS) production, and reduced biofilm formation.",Y Zhang 2019,2019,1 gene,Zhang-2019-Role of a host-induced arginase of,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15891,PHI:10179,UniProt,A0A0D6I594,GenBank,AKH06467,,,YU39,tnpA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,small intestine; cecum; colon,regulatory RNA/ transposase for IS200,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29120256,PubMed,10.1080/15476286.2017.1403001,RNA Biol. 2018 Feb 1;15(2):176-181,haniford@uwo.ca,IS200 elements were important for colonization of the mouse gastrointestinal tract.,M J Ellis 2017,2017,1 gene,Ellis-2017-Silent but deadly_ IS200 promotes p,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15892,PHI:10179,UniProt,A0A0D6I594,GenBank,AKH06467,,,YU39,tnpA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,regulatory RNA/ transposase for IS200,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29120256,PubMed,10.1080/15476286.2017.1403001,RNA Biol. 2018 Feb 1;15(2):176-181,haniford@uwo.ca,IS200 elements were important for colonization of the mouse gastrointestinal tract.,M J Ellis 2017,2017,1 gene,Ellis-2017-Silent but deadly_ IS200 promotes p,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15893,PHI:10179,UniProt,A0A0D6I594,GenBank,AKH06467,,,YU39,tnpA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,regulatory RNA/ transposase for IS200,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29120256,PubMed,10.1080/15476286.2017.1403001,RNA Biol. 2018 Feb 1;15(2):176-181,haniford@uwo.ca,IS200 elements were important for colonization of the mouse gastrointestinal tract.,M J Ellis 2017,2017,1 gene,Ellis-2017-Silent but deadly_ IS200 promotes p,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15894,PHI:10180,UniProt,A0A1B2VWB5,GenBank,AOD41684,,,SC1516,tolC2,,,,,,,715,Actinobacillus pleuropneumoniae,,SC1516,pleuropneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,outer membrane channel component,,,,reduced virulence,,,,,,,,,,no,H2O2; KCl,H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,28758624,PubMed,10.1099/jmm.0.000544,J Med Microbiol. 2017 Aug;66(8):1170-1176,maixiaodonglynn@163.com,"The deletion of tolC2 caused increased sensitivity to oxidative, thermal and acid challenges, indicating a critical role of TolC2 in A. pleuropneumoniae survival under stress conditions.",Y Li 2017,2017,1 gene,Li-2017-TolC2 is required for the resistance,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15895,PHI:10181,UniProt,no data found,GenBank,,,,,RyeC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SB300,salmonellosis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,HCT-116 cell,acid-induced small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29730297,PubMed,10.1016/j.biochi.2018.05.001,Biochimie. 2018 Jul;150:48-56,msuar@kiitbiotech.ac.in,"Over-expression of RyeC in Salmonella produced a general attenuation of several invitro phenotypes including acid survival, motility, adhesion and invasion of epithelial cell lines as well as replication within macrophages.colon carcinoma cell",D Ryan 2018,2018,1 gene,Ryan-2018-Biological and regulatory roles of a,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15896,PHI:10181,UniProt,no data found,GenBank,,,,,RyeC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SB300,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,acid-induced small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,29730297,PubMed,10.1016/j.biochi.2018.05.001,Biochimie. 2018 Jul;150:48-56,msuar@kiitbiotech.ac.in,"Over-expression of RyeC in Salmonella produced a general attenuation of several invitro phenotypes including acid survival, motility, adhesion and invasion of epithelial cell lines as well as replication within macrophages.",D Ryan 2018,2018,1 gene,Ryan-2018-Biological and regulatory roles of a,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15897,PHI:10182,UniProt,A0A194W6H1,GenBank,KUI72106,,,03-8,Pmk1,chromosome 8,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,mitogen-activated protein kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; SDS; H2O2; NaCl,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,28888885,PubMed,10.1016/j.micpath.2017.09.003,Microb Pathog. 2017 Oct;111:298-306,huanglili@nwsuaf.edu.cn,Expression of many cell wall degrading enzyme (CWDE) genes declined in the VmPmk1 deletion mutant during infection.,Y Wu 2017,2017,1 gene,Wu-2017-A mitogen-activated protein kinase gen,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15898,PHI:10183,UniProt,A0A081HZA4,GenBank,KEF96761,,,TKK-01-0059,PtkA,,,,,,,1773,Mycobacterium tuberculosis,419947,H37Ra,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,protein tyrosine kinase transcriptional regulator,,,MEK-JNK-cJUN pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29545176,PubMed,10.1016/j.bbrc.2018.03.075,Biochem Biophys Res Commun. 2018 Apr 15;498(4):884-890,kishore@cdri.res.in,PtkA regulated Galectin 3 level and stimulated host macrophage through MEK-JNK-cJUN pathway and initiated early apoptosis in H37Ra infected macrophage.,S Jaiswal 2018,2018,1 gene,Jaiswal-2018-Protein tyrosine kinase A modulat,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15899,PHI:10183,UniProt,A0A081HZA4,GenBank,KEF96761,,,TKK-01-0059,PtkA,,,,,,,1773,Mycobacterium tuberculosis,419947,H37Ra,tuberculosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,protein tyrosine kinase transcriptional regulator,,,MEK-JNK-cJUN pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29545176,PubMed,10.1016/j.bbrc.2018.03.075,Biochem Biophys Res Commun. 2018 Apr 15;498(4):884-890,kishore@cdri.res.in,PtkA regulated Galectin 3 level and stimulated host macrophage through MEK-JNK-cJUN pathway and initiated early apoptosis in H37Ra infected macrophage.,S Jaiswal 2018,2018,1 gene,Jaiswal-2018-Protein tyrosine kinase A modulat,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15900,PHI:10184,UniProt,P43015,GenBank,AAD12579,,,SL1344,HilA,,K231bmK; K527bmK; K533bmK,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31740807,PubMed,10.1038/s41589-019-0392-5,Nat Chem Biol. 2020 Jan;16(1):95-103,hhang@rockefeller.edu,Site-specific butyrylation of K90 on HilA nearly phenocopied ΔhilA and was sufficient to attenuate S. Typhimurium invasion and dissemination in vivo.,Z J Zhang 2019,2019,1 gene,Zhang-2019-Site-specific acylation of a bacter,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15901,PHI:10184,UniProt,P43015,GenBank,AAD12579,,,SL1344,HilA,,K57bmK; K90bmK; K324bmK; K456bmK,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31740807,PubMed,10.1038/s41589-019-0392-5,Nat Chem Biol. 2020 Jan;16(1):95-103,hhang@rockefeller.edu,Site-specific butyrylation of K90 on HilA nearly phenocopied ΔhilA and was sufficient to attenuate S. Typhimurium invasion and dissemination in vivo.,Z J Zhang 2019,2019,1 gene,Zhang-2019-Site-specific acylation of a bacter,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15902,PHI:10184,UniProt,P43015,GenBank,AAD12579,,,SL1344,HilA,,K57bmK; K90bmK; K231bmK; K324bmK; K456bmK; K527bmK; K533bmK,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31740807,PubMed,10.1038/s41589-019-0392-5,Nat Chem Biol. 2020 Jan;16(1):95-103,hhang@rockefeller.edu,Site-specific butyrylation of K90 on HilA nearly phenocopied ΔhilA and was sufficient to attenuate S. Typhimurium invasion and dissemination in vivo.,Z J Zhang 2019,2019,1 gene,Zhang-2019-Site-specific acylation of a bacter,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15903,PHI:10184,UniProt,P43015,GenBank,AAD12579,,,SL1344,HilA,,K231bmK,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; mesenteric lymph node,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31740807,PubMed,10.1038/s41589-019-0392-5,Nat Chem Biol. 2020 Jan;16(1):95-103,hhang@rockefeller.edu,Site-specific butyrylation of K90 on HilA nearly phenocopied ΔhilA and was sufficient to attenuate S. Typhimurium invasion and dissemination in vivo.,Z J Zhang 2019,2019,1 gene,Zhang-2019-Site-specific acylation of a bacter,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15904,PHI:10184,UniProt,P43015,GenBank,AAD12579,,,SL1344,HilA,,K90bmK,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; mesenteric lymph node,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31740807,PubMed,10.1038/s41589-019-0392-5,Nat Chem Biol. 2020 Jan;16(1):95-103,hhang@rockefeller.edu,Site-specific butyrylation of K90 on HilA nearly phenocopied ΔhilA and was sufficient to attenuate S. Typhimurium invasion and dissemination in vivo.,Z J Zhang 2019,2019,1 gene,Zhang-2019-Site-specific acylation of a bacter,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15905,PHI:10184,UniProt,P43015,GenBank,AAD12579,,,SL1344,HilA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; mesenteric lymph node,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31740807,PubMed,10.1038/s41589-019-0392-5,Nat Chem Biol. 2020 Jan;16(1):95-103,hhang@rockefeller.edu,Site-specific butyrylation of K90 on HilA nearly phenocopied ΔhilA and was sufficient to attenuate S. Typhimurium invasion and dissemination in vivo.,Z J Zhang 2019,2019,1 gene,Zhang-2019-Site-specific acylation of a bacter,BATCH_100A,2020-04-01,MC,,,,,,,,,,,,,
,,Record 15906,PHI:5881,UniProt,I1R9N9,Ensembl Genomes,FgramPH1_01T00521,,,PH-1,PRB1,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15907,PHI:5882,UniProt,I1SAE5,Ensembl Genomes,FgramPH1_01T21527,,,PH-1,FGSG_13826,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15908,PHI:5883,UniProt,A0A098DNT5,Ensembl Genomes,FgramPH1_01T15643,,,PH-1,FGSG_12224,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15909,PHI:5884,UniProt,A0A098DI68,Ensembl Genomes,FgramPH1_01T11705,,,PH-1,FGSG_12545,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15910,PHI:5885,UniProt,A0A098DBM1,Ensembl Genomes,FgramPH1_01T08093,,,PH-1,FGSG_10432,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15911,PHI:5886,UniProt,I1RB96,Ensembl Genomes,FgramPH1_01T02019,,,PH-1,FGSG_00806,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15912,PHI:5887,UniProt,A0A098DK85,Ensembl Genomes,FgramPH1_01T15137,,,PH-1,FGSG_04375,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15913,PHI:5888,UniProt,A0A1C3YN95,Ensembl Genomes,FgramPH1_01T15469,,,PH-1,FGSG_12242,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15914,PHI:5889,UniProt,I1RUV5,Ensembl Genomes,FgramPH1_01T08909,,,PH-1,FGSG_08012,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15915,PHI:5890,UniProt,I1RW12,Ensembl Genomes,FgramPH1_01T10027,,,PH-1,FGSG_08464,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15916,PHI:5891,UniProt,A0A1C3YLU4,Ensembl Genomes,FgramPH1_01T27889,,,PH-1,FGSG_09115,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15917,PHI:5892,UniProt,A0A1C3YLW9,Ensembl Genomes,FgramPH1_01T27223,,,PH-1,FGSG_09382,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15918,PHI:5893,UniProt,I1S1C5,Ensembl Genomes,FgramPH1_01T08331,,,PH-1,FGSG_10525,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15919,PHI:5894,UniProt,I1S1J0,Ensembl Genomes,FgramPH1_01T08489,,,PH-1,FGSG_10595,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15920,PHI:5895,UniProt,I1S1U2,Ensembl Genomes,FgramPH1_01T08759,,,PH-1,FGSG_10712,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15921,PHI:5896,UniProt,A0A1C3YKT7,Ensembl Genomes,FgramPH1_01T21981,,,PH-1,FGSG_11405,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15922,PHI:5897,UniProt,I1RGU8,Ensembl Genomes,FgramPH1_01T11753,,,PH-1,FGSG_02976,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15923,PHI:5898,UniProt,I1RHQ4,Ensembl Genomes,FgramPH1_01T12585,,,PH-1,FGSG_03315,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15924,PHI:5899,UniProt,I1RR60,Ensembl Genomes,FgramPH1_01T22617,,,PH-1,FGSG_06572,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15925,PHI:5900,UniProt,I1S3S6,Ensembl Genomes,FgramPH1_01T22149,,,PH-1,FGSG_11472,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15926,PHI:5901,UniProt,I1RH33,Ensembl Genomes,FgramPH1_01T11987,,,PH-1,FGSG_03072,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15927,PHI:5902,UniProt,I1S0V3,Ensembl Genomes,FgramPH1_01T07871,,,PH-1,FGSG_10343,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15928,PHI:5903,UniProt,I1S5M1,Ensembl Genomes,FgramPH1_01T05915,,,PH-1,FGSG_12142,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium ear blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,MU,32890707,PubMed,10.1016/j.fgb.2020.103449,Fungal Genet Biol. 2020 Sep 2;144:103449.,chenahai0717@126.com,,Xu et al 2020,2020,,,MU curated Sept 2020 for 4.10 release,2020-09-01,RRes,,,,,,,,,,,,,
,,Record 15929,PHI:10185,UniProt,Q48473,GenBank,CAA83913,,,C3,OmpK36,,,,,,PHI:10186,573,Klebsiella pneumoniae,,ATCC 43816,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane porin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31010630,PubMed,10.1016/j.ijmm.2019.04.001,Int J Med Microbiol. 2019 May - Jun;309(3-4):213-224,terri.ellis@unf.edu,Loss of OmpK35 alone or dual porin loss was further associated with reduced oxidative burst by macrophages and increased ability of the bacteria to survive phagocytic killing.,D N Brunson 2019,2019,2 genes,Brunson-2019-Porin loss in Klebsiella pneumoni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15930,PHI:10186,UniProt,O87753,GenBank,ADG27466,,,KP187/08,OmpK35,,,,,,PHI:10185,573,Klebsiella pneumoniae,,ATCC 43816,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane porin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31010630,PubMed,10.1016/j.ijmm.2019.04.001,Int J Med Microbiol. 2019 May - Jun;309(3-4):213-224,terri.ellis@unf.edu,Loss of OmpK35 alone or dual porin loss was further associated with reduced oxidative burst by macrophages and increased ability of the bacteria to survive phagocytic killing.,D N Brunson 2019,2019,2 genes,Brunson-2019-Porin loss in Klebsiella pneumoni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15931,PHI:10185,UniProt,Q48473,GenBank,CAA83913,,,C3,OmpK36,,,,,,,573,Klebsiella pneumoniae,,ATCC 43816,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane porin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31010630,PubMed,10.1016/j.ijmm.2019.04.001,Int J Med Microbiol. 2019 May - Jun;309(3-4):213-224,terri.ellis@unf.edu,Loss of OmpK35 alone or dual porin loss was further associated with reduced oxidative burst by macrophages and increased ability of the bacteria to survive phagocytic killing.,D N Brunson 2019,2019,2 genes,Brunson-2019-Porin loss in Klebsiella pneumoni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15932,PHI:10186,UniProt,O87753,GenBank,ADG27466,,,KP187/08,OmpK35,,,,,,,573,Klebsiella pneumoniae,,ATCC 43816,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane porin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31010630,PubMed,10.1016/j.ijmm.2019.04.001,Int J Med Microbiol. 2019 May - Jun;309(3-4):213-224,terri.ellis@unf.edu,Loss of OmpK35 alone or dual porin loss was further associated with reduced oxidative burst by macrophages and increased ability of the bacteria to survive phagocytic killing.,D N Brunson 2019,2019,2 genes,Brunson-2019-Porin loss in Klebsiella pneumoni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15933,PHI:10187,UniProt,no data found,GenBank,,,,,TTSS-1,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,ileum; cecum; liver; spleen,type III secretion system 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,30396895,PubMed,10.1128/IAI.00503-18,Infect Immun. 2018 Dec 19;87(1),cre43@cornell.edu,"Coinoculation of an SPI-1 mutant with the wild-type strain increased the number of mutant organisms in intestinal tissue and contents, suggesting that the wild type rescues the mutant.",C R Eade 2018,2018,1 gene,Eade-2018-Salmonella Pathogenicity Island One,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15934,PHI:10187,UniProt,no data found,GenBank,,,,,TTSS-1,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,birds,9031,Gallus gallus (related: chicken),Leghorn,,,ileum; cecum; liver; spleen,type III secretion system 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,30396895,PubMed,10.1128/IAI.00503-18,Infect Immun. 2018 Dec 19;87(1),cre43@cornell.edu,"Coinoculation of an SPI-1 mutant with the wild-type strain increased the number of mutant organisms in intestinal tissue and contents, suggesting that the wild type rescues the mutant.",C R Eade 2018,2018,1 gene,Eade-2018-Salmonella Pathogenicity Island One,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15935,PHI:10188,UniProt,A0A2H4QBA5,GenBank,ATX61795,,,KK002,modK1,,,,,,,504,Kingella kingae,,KK003,skeletal disease (children); infective endocarditis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,adenine specific DNA methylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28947652,PubMed,10.1128/IAI.00319-17,Infect Immun. 2017 Nov 17;85(12),yogitha.srikhanta@monash.edu,ModK1 phasevarion influences the host inflammatory response and provides the first evidence of this phase variable epigenetic mechanism of gene regulation in K. kingae.,Y N Srikhanta 2017,2017,2 genes,Srikhanta-2017-Phasevarion regulated virulence,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15936,PHI:10189,UniProt,A0A1X7QMH9,GenBank,SMH72683,,,PED21,rtxA,,,,,,,504,Kingella kingae,,KK003,skeletal disease (children); infective endocarditis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,"Ca2+-binding protein, RTX toxin-related",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,28947652,PubMed,10.1128/IAI.00319-17,Infect Immun. 2017 Nov 17;85(12),yogitha.srikhanta@monash.edu,"90 min post infection, the toxin had a significant role in the suppression of neutrophilrecruitment (IL-8) and apoptosis (TNF).",Y N Srikhanta 2017,2017,2 genes,Srikhanta-2017-Phasevarion regulated virulence,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15937,PHI:10190,UniProt,Q8ZNG2,GenBank,AAL21188,,,LT2,sseL,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31091452,PubMed,10.1016/j.celrep.2019.04.021,Cell Rep. 2019 May 14;27(7):2147-2156.e5,millersi@uw.edu,Host gene alteration data available for oxysterol binding protein 1 (OSBP1). Deletion of both SseJ and SseL reduced vacuolar integrity with increased bacteria released into the eukaryotic cytoplasm of epithelial cells.,A M Kolodziejek 2019,2019,2 genes,Kolodziejek-2019-Salmonella Translocated Effec,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15938,PHI:10191,UniProt,Q9FD10,GenBank,AF294582_1,,,SGSC1412,SseJ,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31091452,PubMed,10.1016/j.celrep.2019.04.021,Cell Rep. 2019 May 14;27(7):2147-2156.e5,millersi@uw.edu,Host gene alteration data available for oxysterol binding protein 1 (OSBP1). Deletion of both SseJ and SseL reduced vacuolar integrity with increased bacteria released into the eukaryotic cytoplasm of epithelial cells.,A M Kolodziejek 2019,2019,2 genes,Kolodziejek-2019-Salmonella Translocated Effec,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15939,PHI:10190,UniProt,Q8ZNG2,GenBank,AAL21188,,,LT2,sseL,,,,,,PHI:10191,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31091452,PubMed,10.1016/j.celrep.2019.04.021,Cell Rep. 2019 May 14;27(7):2147-2156.e5,millersi@uw.edu,Host gene alteration data available for oxysterol binding protein 1 (OSBP1). Deletion of both SseJ and SseL reduced vacuolar integrity with increased bacteria released into the eukaryotic cytoplasm of epithelial cells.,A M Kolodziejek 2019,2019,2 genes,Kolodziejek-2019-Salmonella Translocated Effec,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15940,PHI:10191,UniProt,Q9FD10,GenBank,AF294582_1,,,SGSC1412,SseJ,,,,,,PHI:10190,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31091452,PubMed,10.1016/j.celrep.2019.04.021,Cell Rep. 2019 May 14;27(7):2147-2156.e5,millersi@uw.edu,Host gene alteration data available for oxysterol binding protein 1 (OSBP1). Deletion of both SseJ and SseL reduced vacuolar integrity with increased bacteria released into the eukaryotic cytoplasm of epithelial cells.,A M Kolodziejek 2019,2019,2 genes,Kolodziejek-2019-Salmonella Translocated Effec,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15941,PHI:10192,UniProt,Q59MD2,GenBank,AOW26289,,,SC5314,ume6,chromosome 1,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,stomach; jejunum; ileum; cecum; large intestine,transcriptional regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30870623,PubMed,10.1016/j.chom.2019.02.008,Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6,suzanne.noble@ucsf.edu,"Ume6, a master regulator of ?lamentation, inhibited gut colonization by activating the expression of a hypha-speci?c pro-inflammatory secreted protease, Sap6, and a hyphal cell surface adhesin, Hyr1.",J N Witchley 2019,2019,7 genes,Witchley-2019-Candida albicans Morphogenesis P,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15942,PHI:10192,UniProt,Q59MD2,GenBank,AOW26289,,,SC5314,ume6,chromosome 1,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,stomach; jejunum; ileum; cecum; large intestine,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30870623,PubMed,10.1016/j.chom.2019.02.008,Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6,suzanne.noble@ucsf.edu,"Ume6, a master regulator of ?lamentation, inhibited gut colonization by activating the expression of a hypha-speci?c pro-inflammatory secreted protease, Sap6, and a hyphal cell surface adhesin, Hyr1.",J N Witchley 2019,2019,7 genes,Witchley-2019-Candida albicans Morphogenesis P,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15943,PHI:10193,UniProt,Q5AC08,GenBank,AOW30203,,,SC5314,sap6,chromosome 6,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,stomach; jejunum; ileum; cecum; large intestine,candidapepsin-6,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30870623,PubMed,10.1016/j.chom.2019.02.008,Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6,suzanne.noble@ucsf.edu,"Ume6, a master regulator of ?lamentation, inhibited gut colonization by activating the expression of a hypha-speci?c pro-inflammatory secreted protease, Sap6, and a hyphal cell surface adhesin, Hyr1.",J N Witchley 2019,2019,7 genes,Witchley-2019-Candida albicans Morphogenesis P,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15944,PHI:10193,UniProt,Q5AC08,GenBank,AOW30203,,,SC5314,sap6,chromosome 6,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,stomach; jejunum; ileum; cecum; large intestine,candidapepsin-6,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30870623,PubMed,10.1016/j.chom.2019.02.008,Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6,suzanne.noble@ucsf.edu,"Ume6, a master regulator of ?lamentation, inhibited gut colonization by activating the expression of a hypha-speci?c pro-inflammatory secreted protease, Sap6, and a hyphal cell surface adhesin, Hyr1.",J N Witchley 2019,2019,7 genes,Witchley-2019-Candida albicans Morphogenesis P,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15945,PHI:10194,UniProt,Q5AL03,GenBank,AOW26950,,,SC5314,hyr1,chromosome 1,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,stomach; jejunum; ileum; cecum; large intestine,hyphally regulated cell wall protein 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30870623,PubMed,10.1016/j.chom.2019.02.008,Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6,suzanne.noble@ucsf.edu,"Ume6, a master regulator of ?lamentation, inhibited gut colonization by activating the expression of a hypha-speci?c pro-inflammatory secreted protease, Sap6, and a hyphal cell surface adhesin, Hyr1.",J N Witchley 2019,2019,7 genes,Witchley-2019-Candida albicans Morphogenesis P,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15946,PHI:10195,UniProt,Q59X67,GenBank,AOW31479,,,SC5314,efg1,chromosome R,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,stomach; jejunum; ileum; cecum; large intestine,enhanced filamentous growth protein 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30870623,PubMed,10.1016/j.chom.2019.02.008,Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6,suzanne.noble@ucsf.edu,"Ume6, a master regulator of ?lamentation, inhibited gut colonization by activating the expression of a hypha-speci?c pro-inflammatory secreted protease, Sap6, and a hyphal cell surface adhesin, Hyr1.",J N Witchley 2019,2019,7 genes,Witchley-2019-Candida albicans Morphogenesis P,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15947,PHI:10196,UniProt,Q59LY1,GenBank,AOW26184,,,SC5314,brg1,chromosome 1,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,stomach; jejunum; ileum; cecum; large intestine,biofilm regulator 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30870623,PubMed,10.1016/j.chom.2019.02.008,Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6,suzanne.noble@ucsf.edu,"Ume6, a master regulator of ?lamentation, inhibited gut colonization by activating the expression of a hypha-speci?c pro-inflammatory secreted protease, Sap6, and a hyphal cell surface adhesin, Hyr1.",J N Witchley 2019,2019,7 genes,Witchley-2019-Candida albicans Morphogenesis P,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15948,PHI:10197,UniProt,A0A1D8PFP2,GenBank,AOW26964,,,SC5314,rob1,chromosome 1,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,stomach; jejunum; ileum; cecum; large intestine,Zn(II)2Cys6 transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30870623,PubMed,10.1016/j.chom.2019.02.008,Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6,suzanne.noble@ucsf.edu,"Ume6, a master regulator of ?lamentation, inhibited gut colonization by activating the expression of a hypha-speci?c pro-inflammatory secreted protease, Sap6, and a hyphal cell surface adhesin, Hyr1.",J N Witchley 2019,2019,7 genes,Witchley-2019-Candida albicans Morphogenesis P,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15949,PHI:10198,UniProt,Q5ANJ4,GenBank,AOW28471,,,SC5314,tec1,chromosome 3,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,stomach; jejunum; ileum; cecum; large intestine,transcription activator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30870623,PubMed,10.1016/j.chom.2019.02.008,Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6,suzanne.noble@ucsf.edu,"Ume6, a master regulator of ?lamentation, inhibited gut colonization by activating the expression of a hypha-speci?c pro-inflammatory secreted protease, Sap6, and a hyphal cell surface adhesin, Hyr1.",J N Witchley 2019,2019,7 genes,Witchley-2019-Candida albicans Morphogenesis P,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15950,PHI:10199,UniProt,P13482,GenBank,AAC74281,,,K-12,treA,,,,,,,562,Escherichia coli,,MT78,urinary tract infection,birds,9031,Gallus gallus (related: chicken),CEC-32 cell line,,,fibroblast cell line,periplasmic trehalase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29844238,PubMed,10.1128/IAI.00241-18,Infect Immun. 2018 Jul 23;86(8):e00241-18,fabiana.horn@ufrgs.br,The treA mutant is less adherent and invasive for avian cells.,D B Pavanelo 2018,2018,1 gene,Pavanelo-2018-The periplasmic trehalase affect,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15951,PHI:10199,UniProt,P13482,GenBank,AAC74281,,,K-12,treA,,,,,,,562,Escherichia coli,,MT78,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,bladder,periplasmic trehalase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29844238,PubMed,10.1128/IAI.00241-18,Infect Immun. 2018 Jul 23;86(8):e00241-18,fabiana.horn@ufrgs.br,Loss of treA significantly reduced its cell invasion capacity and colonization of the bladder in a murine model of urinary tract infection.,D B Pavanelo 2018,2018,1 gene,Pavanelo-2018-The periplasmic trehalase affect,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15952,PHI:10199,UniProt,P13482,GenBank,AAC74281,,,K-12,treA,,,,,,,562,Escherichia coli,,MT78,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney,periplasmic trehalase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,29844238,PubMed,10.1128/IAI.00241-18,Infect Immun. 2018 Jul 23;86(8):e00241-18,fabiana.horn@ufrgs.br,Loss of treA significantly reduced its cell invasion capacity and colonization of the bladder in a murine model of urinary tract infection.,D B Pavanelo 2018,2018,1 gene,Pavanelo-2018-The periplasmic trehalase affect,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15953,PHI:10200,UniProt,A0A194VW85,GenBank,KUI68257,,,,DCL1,chromosome 4,,,,,,105487,Valsa mali,,03-8,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,dicer-like protein 1,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; KCl,H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion full; gene complementation,,,YVS,28690605,PubMed,10.3389/fmicb.2017.01166.eCollection 2017.Erratum in: Front Microbiol.2017 Jul 28;8:1457,Front Microbiol. 2017 Jun 23;8:1166,huanglili@nwsuaf.edu.cn,"VmDCLs function in the H2O2 and KCl stress response, pathogenicity and generation of sRNAs.",H Feng 2017,2017,2 genes,Feng-2017-Dicer-Like Genes Are Required for H2,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15954,PHI:10201,UniProt,A0A194WBI8,GenBank,KUI73784,,,,DCL2,chromosome 11,,,,,,105487,Valsa mali,,03-8,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,dicer-like protein 2,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; KCl,H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion full; gene complementation,,,YVS,28690605,PubMed,10.3389/fmicb.2017.01166.eCollection 2017.Erratum in: Front Microbiol.2017 Jul 28;8:1457,Front Microbiol. 2017 Jun 23;8:1166,huanglili@nwsuaf.edu.cn,"VmDCLs function in the H2O2 and KCl stress response, pathogenicity and generation of sRNAs.",H Feng 2017,2017,2 genes,Feng-2017-Dicer-Like Genes Are Required for H2,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15955,PHI:10200,UniProt,A0A194VW85,GenBank,KUI68257,,,,DCL1,chromosome 4,,,,,PHI:10201,105487,Valsa mali,,03-8,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,dicer-like protein 1,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; KCl,H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion full; gene complementation,,,YVS,28690605,PubMed,10.3389/fmicb.2017.01166.eCollection 2017.Erratum in: Front Microbiol.2017 Jul 28;8:1457,Front Microbiol. 2017 Jun 23;8:1166,huanglili@nwsuaf.edu.cn,"VmDCLs function in the H2O2 and KCl stress response, pathogenicity and generation of sRNAs.",H Feng 2017,2017,2 genes,Feng-2017-Dicer-Like Genes Are Required for H2,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15956,PHI:10201,UniProt,A0A194WBI8,GenBank,KUI73784,,,,DCL2,chromosome 11,,,,,PHI:10200,105487,Valsa mali,,03-8,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,dicer-like protein 2,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; KCl,H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion full; gene complementation,,,YVS,28690605,PubMed,10.3389/fmicb.2017.01166.eCollection 2017.Erratum in: Front Microbiol.2017 Jul 28;8:1457,Front Microbiol. 2017 Jun 23;8:1166,huanglili@nwsuaf.edu.cn,"VmDCLs function in the H2O2 and KCl stress response, pathogenicity and generation of sRNAs.",H Feng 2017,2017,2 genes,Feng-2017-Dicer-Like Genes Are Required for H2,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15957,PHI:10203,UniProt,Q2FZ27,GenBank,KHF80889,,,UAMS-1,CodY (QV15_05910),,,,,,,1280,Staphylococcus aureus,,UAMS-1,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,neutrophil,GTP-sensing transcriptional pleiotropic repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29378891,PubMed,10.1128/JB.00012-18,J Bacteriol. 2018 Mar 26;200(8),shaun.brinsmade@georgetown.edu,CodY acted as a master regulator of pathogenesis by tying nutrient availability to virulence gene expression.,K D Mlynek 2018,2018,2 genes,Mlynek-2018-Nutritional regulation of the Sae,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15958,PHI:10203,UniProt,Q2FZ27,GenBank,KHF80889,,,UAMS-1,CodY (QV15_05910),,,,,,PHI:10204,1280,Staphylococcus aureus,,UAMS-1,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,neutrophil,GTP-sensing transcriptional pleiotropic repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29378891,PubMed,10.1128/JB.00012-18,J Bacteriol. 2018 Mar 26;200(8),shaun.brinsmade@georgetown.edu,CodY acted as a master regulator of pathogenesis by tying nutrient availability to virulence gene expression.,K D Mlynek 2018,2018,2 genes,Mlynek-2018-Nutritional regulation of the Sae,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15959,PHI:10204,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,PHI:10203,1280,Staphylococcus aureus,,UAMS-1,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,neutrophil,GTP-sensing transcriptional pleiotropic repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29378891,PubMed,10.1128/JB.00012-18,J Bacteriol. 2018 Mar 26;200(8),shaun.brinsmade@georgetown.edu,CodY acted as a master regulator of pathogenesis by tying nutrient availability to virulence gene expression.,K D Mlynek 2018,2018,2 genes,Mlynek-2018-Nutritional regulation of the Sae,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15960,PHI:10205,UniProt,G3FT04,GenBank,AEO27492,,,AJ218,mrkA,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,major pilin subunit of type 3 fimbriae,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29158434,PubMed,10.1128/IAI.00647-17,Infect Immun. 2018 Jan 22;86(2),rosend@wustl.edu,Attenuation of K. pneumoniae virulence by high c-di-GMP levels was abrogated when type 1 pilus expression was silenced.,D A Rosen 2017,2017,10 genes,Rosen-2017-High Levels of Cyclic di-GMP in Kle,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15961,PHI:10206,UniProt,no data found,GenBank,,,,,fimS,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,fimbrial protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29158434,PubMed,10.1128/IAI.00647-17,Infect Immun. 2018 Jan 22;86(2),rosend@wustl.edu,Attenuation of K. pneumoniae virulence by high c-di-GMP levels was abrogated when type 1 pilus expression was silenced.,D A Rosen 2017,2017,10 genes,Rosen-2017-High Levels of Cyclic di-GMP in Kle,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15962,PHI:10207,UniProt,A0A0S3FFR9,GenBank,AUU95694,,,KPNIH49,fimA,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,fimbrial protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29158434,PubMed,10.1128/IAI.00647-17,Infect Immun. 2018 Jan 22;86(2),rosend@wustl.edu,Attenuation of K. pneumoniae virulence by high c-di-GMP levels was abrogated when type 1 pilus expression was silenced.,D A Rosen 2017,2017,10 genes,Rosen-2017-High Levels of Cyclic di-GMP in Kle,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15963,PHI:10208,UniProt,B0LF83,GenBank,ABW24954,,,3091,fimI,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,pilin (type 1 fimbria component protein),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29158434,PubMed,10.1128/IAI.00647-17,Infect Immun. 2018 Jan 22;86(2),rosend@wustl.edu,Attenuation of K. pneumoniae virulence by high c-di-GMP levels was abrogated when type 1 pilus expression was silenced.,D A Rosen 2017,2017,10 genes,Rosen-2017-High Levels of Cyclic di-GMP in Kle,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15964,PHI:10209,UniProt,A0A086ITU0,GenBank,AUU95693,,,KPNIH49,fimC,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,molecular chaperone,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29158434,PubMed,10.1128/IAI.00647-17,Infect Immun. 2018 Jan 22;86(2),rosend@wustl.edu,Attenuation of K. pneumoniae virulence by high c-di-GMP levels was abrogated when type 1 pilus expression was silenced.,D A Rosen 2017,2017,10 genes,Rosen-2017-High Levels of Cyclic di-GMP in Kle,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15965,PHI:10210,UniProt,A0A2X3EJX6,GenBank,SQC44282,,,NCTC13465,fimD,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,type 1 fimbriae anchoring protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29158434,PubMed,10.1128/IAI.00647-17,Infect Immun. 2018 Jan 22;86(2),rosend@wustl.edu,Attenuation of K. pneumoniae virulence by high c-di-GMP levels was abrogated when type 1 pilus expression was silenced.,D A Rosen 2017,2017,10 genes,Rosen-2017-High Levels of Cyclic di-GMP in Kle,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15966,PHI:10211,UniProt,A0A0T5I632,GenBank,SBY39291,,,PB463,fimF,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,putative fimbrial subunit,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29158434,PubMed,10.1128/IAI.00647-17,Infect Immun. 2018 Jan 22;86(2),rosend@wustl.edu,Attenuation of K. pneumoniae virulence by high c-di-GMP levels was abrogated when type 1 pilus expression was silenced.,D A Rosen 2017,2017,10 genes,Rosen-2017-High Levels of Cyclic di-GMP in Kle,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15967,PHI:10212,UniProt,B0LF87,GenBank,ABW24958,,,3091,fimG,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,pilin (type 1 fimbria component protein),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29158434,PubMed,10.1128/IAI.00647-17,Infect Immun. 2018 Jan 22;86(2),rosend@wustl.edu,Attenuation of K. pneumoniae virulence by high c-di-GMP levels was abrogated when type 1 pilus expression was silenced.,D A Rosen 2017,2017,10 genes,Rosen-2017-High Levels of Cyclic di-GMP in Kle,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15968,PHI:10213,UniProt,B0LF88,GenBank,ABW24959,,,3091,fimH,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,type 1 fimbriae adhesin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29158434,PubMed,10.1128/IAI.00647-17,Infect Immun. 2018 Jan 22;86(2),rosend@wustl.edu,Attenuation of K. pneumoniae virulence by high c-di-GMP levels was abrogated when type 1 pilus expression was silenced.,D A Rosen 2017,2017,10 genes,Rosen-2017-High Levels of Cyclic di-GMP in Kle,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15969,PHI:10214,UniProt,Q08859,GenBank,AAA25064,,,,fimK,,,,,,,573,Klebsiella pneumoniae,,TOP52,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,fimbrial adhesin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29158434,PubMed,10.1128/IAI.00647-17,Infect Immun. 2018 Jan 22;86(2),rosend@wustl.edu,Attenuation of K. pneumoniae virulence by high c-di-GMP levels was abrogated when type 1 pilus expression was silenced.,D A Rosen 2017,2017,10 genes,Rosen-2017-High Levels of Cyclic di-GMP in Kle,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15970,PHI:10215,UniProt,G8CP73,GenBank,AEQ93530,,,,pumA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,putative addiction module killer protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28970172,PubMed,10.1016/j.micpath.2017.09.060,Microb Pathog. 2017 Nov;112:259-268,marthaisela_ramirez@hotmail.com,PumAB genes encoded a Toxin-Antitoxin system where the PumB protein countered the toxic effects of the PumA toxin.,K C Hernandez-Ramirez 2017,2017,2 genes,Hernandez-Ramir-2017-Plasmid pUM505 encodes a,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15971,PHI:10216,UniProt,G8CP74,GenBank,AEQ93531,,,,pumB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,helix-turn-helix XRE-family like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28970172,PubMed,10.1016/j.micpath.2017.09.060,Microb Pathog. 2017 Nov;112:259-268,marthaisela_ramirez@hotmail.com,PumAB genes encoded a Toxin-Antitoxin system where the PumB protein countered the toxic effects of the PumA toxin.,K C Hernandez-Ramirez 2017,2017,2 genes,Hernandez-Ramir-2017-Plasmid pUM505 encodes a,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15972,PHI:10215,UniProt,G8CP73,GenBank,AEQ93530,,,,pumA,,,,,,PHI:10216,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,putative addiction module killer protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28970172,PubMed,10.1016/j.micpath.2017.09.060,Microb Pathog. 2017 Nov;112:259-268,marthaisela_ramirez@hotmail.com,PumAB genes encoded a Toxin-Antitoxin system where the PumB protein countered the toxic effects of the PumA toxin.,K C Hernandez-Ramirez 2017,2017,2 genes,Hernandez-Ramir-2017-Plasmid pUM505 encodes a,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15973,PHI:10216,UniProt,G8CP74,GenBank,AEQ93531,,,,pumB,,,,,,PHI:10215,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,helix-turn-helix XRE-family like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28970172,PubMed,10.1016/j.micpath.2017.09.060,Microb Pathog. 2017 Nov;112:259-268,marthaisela_ramirez@hotmail.com,PumAB genes encoded a Toxin-Antitoxin system where the PumB protein countered the toxic effects of the PumA toxin.,K C Hernandez-Ramirez 2017,2017,2 genes,Hernandez-Ramir-2017-Plasmid pUM505 encodes a,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15974,PHI:10215,UniProt,G8CP73,GenBank,AEQ93530,,,,pumA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; lung; kidney,,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28970172,PubMed,10.1016/j.micpath.2017.09.060,Microb Pathog. 2017 Nov;112:259-268,marthaisela_ramirez@hotmail.com,PumAB genes encoded a Toxin-Antitoxin system where the PumB protein countered the toxic effects of the PumA toxin.,K C Hernandez-Ramirez 2017,2017,2 genes,Hernandez-Ramir-2017-Plasmid pUM505 encodes a,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15975,PHI:10216,UniProt,G8CP74,GenBank,AEQ93531,,,,pumB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart,,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28970172,PubMed,10.1016/j.micpath.2017.09.060,Microb Pathog. 2017 Nov;112:259-268,marthaisela_ramirez@hotmail.com,PumAB genes encoded a Toxin-Antitoxin system where the PumB protein countered the toxic effects of the PumA toxin.,K C Hernandez-Ramirez 2017,2017,2 genes,Hernandez-Ramir-2017-Plasmid pUM505 encodes a,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15976,PHI:10215,UniProt,G8CP73,GenBank,AEQ93530,,,,pumA,,,,,,PHI:10216,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; lung; kidney,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28970172,PubMed,10.1016/j.micpath.2017.09.060,Microb Pathog. 2017 Nov;112:259-268,marthaisela_ramirez@hotmail.com,PumAB genes encoded a Toxin-Antitoxin system where the PumB protein countered the toxic effects of the PumA toxin.,K C Hernandez-Ramirez 2017,2017,2 genes,Hernandez-Ramir-2017-Plasmid pUM505 encodes a,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15977,PHI:10216,UniProt,G8CP74,GenBank,AEQ93531,,,,pumB,,,,,,PHI:10215,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; lung; kidney,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28970172,PubMed,10.1016/j.micpath.2017.09.060,Microb Pathog. 2017 Nov;112:259-268,marthaisela_ramirez@hotmail.com,PumAB genes encoded a Toxin-Antitoxin system where the PumB protein countered the toxic effects of the PumA toxin.,K C Hernandez-Ramirez 2017,2017,2 genes,Hernandez-Ramir-2017-Plasmid pUM505 encodes a,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15978,PHI:10216,UniProt,G8CP74,GenBank,AEQ93531,,,,pumB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; kidney,,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28970172,PubMed,10.1016/j.micpath.2017.09.060,Microb Pathog. 2017 Nov;112:259-268,marthaisela_ramirez@hotmail.com,PumAB genes encoded a Toxin-Antitoxin system where the PumB protein countered the toxic effects of the PumA toxin.,K C Hernandez-Ramirez 2017,2017,2 genes,Hernandez-Ramir-2017-Plasmid pUM505 encodes a,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15979,PHI:10217,UniProt,no data found,GenBank,,,,,VdmilR1,,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,miRNA-like small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30967013,PubMed,10.1098/rstb.2018.0309,Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180309,guohs@im.ac.cn,VdHy1 was essential for fungal virulence.,Y Jin 2019,2019,2 genes,Jin-2019-A fungal milRNA mediates epigenetic r,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15980,PHI:10218,UniProt,G2XDV1,GenBank,EGY17999,,,VdLs.17,Vdhy1 (VDAG_08333),,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30967013,PubMed,10.1098/rstb.2018.0309,Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180309,guohs@im.ac.cn,VdHy1 was essential for fungal virulence.,Y Jin 2019,2019,2 genes,Jin-2019-A fungal milRNA mediates epigenetic r,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15981,PHI:10219,UniProt,A0A194VQ92,GenBank,KUI65995,,,03–8,FAEA1 (VM1G_01793),chromosome 2,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,putative feruloyl esterase A,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15982,PHI:10220,UniProt,no data found,GenBank,,,,,FAEB1 (VM09901),,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15983,PHI:10221,UniProt,no data found,GenBank,,,,,FAEC1 (VM04403),,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15984,PHI:10222,UniProt,A0A194VK59,GenBank,KUI64534,,,03–8,FAEC2 (VM1G_00022),chromosome 1,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,carboxylic ester hydrolase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15985,PHI:10223,UniProt,A0A194W2D2,GenBank,KUI70248,,,03–8,FAEC3 (VM1G_06347),chromosome 6,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,putative feruloyl esterase B-2,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15986,PHI:10224,UniProt,A0A194W3E0,GenBank,KUI70598,,,03–8,FAED1 (VM1G_06527),chromosome 6,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase B,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15987,PHI:10225,UniProt,A0A194VKY8,GenBank,KUI64826,,,03–8,FAED2 (VM1G_00901),chromosome 1,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase B,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15988,PHI:10220,UniProt,no data found,GenBank,,,,,FAEB1 (VM09901),,,,,,PHI:10221,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15989,PHI:10221,UniProt,no data found,GenBank,,,,,FAEC1 (VM04403),,,,,,PHI:10220,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15990,PHI:10220,UniProt,no data found,GenBank,,,,,FAEB1 (VM09901),,,,,,PHI:10224,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15991,PHI:10224,UniProt,A0A194W3E0,GenBank,KUI70598,,,03–8,FAED1 (VM1G_06527),chromosome 6,,,,,PHI:10220,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase B,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15992,PHI:10224,UniProt,A0A194W3E0,GenBank,KUI70598,,,03–8,FAED1 (VM1G_06527),chromosome 6,,,,,PHI:10225,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase B,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15993,PHI:10225,UniProt,A0A194VKY8,GenBank,KUI64826,,,03–8,FAED2 (VM1G_00901),chromosome 1,,,,,PHI:10224,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase B,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15994,PHI:10219,UniProt,A0A194VQ92,GenBank,KUI65995,,,03–8,FAEA1 (VM1G_01793),chromosome 2,,,,,PHI:10220,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,putative feruloyl esterase A,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15995,PHI:10220,UniProt,no data found,GenBank,,,,,FAEB1 (VM09901),,,,,,PHI:10219,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15996,PHI:10221,UniProt,no data found,GenBank,,,,,FAEC1 (VM04403),,,,,,PHI:10222,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15997,PHI:10222,UniProt,A0A194VK59,GenBank,KUI64534,,,03–8,FAEC2 (VM1G_00022),chromosome 1,,,,,PHI:10221,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,carboxylic ester hydrolase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15998,PHI:10221,UniProt,no data found,GenBank,,,,,FAEC1 (VM04403),,,,,,PHI:10224,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 15999,PHI:10224,UniProt,A0A194W3E0,GenBank,KUI70598,,,03–8,FAED1 (VM1G_06527),chromosome 6,,,,,PHI:10221,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,feruloyl esterase B,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28960871,PubMed,10.1111/mpp.12619,Mol Plant Pathol. 2018 Jun;19(6):1353-1363,gxning@nwsuaf.edu.cn,Secreted FAEs were required for the full pathogenicity of the phytopathogenic fungus V. mali.,M Xu 2017,2017,7 genes,Xu-2017-The feruloyl esterase genes are requir,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16000,PHI:10226,UniProt,B9A8A3,GenBank,BAH16702,,,SA83,Cnm,,,,,,,1309,Streptococcus mutans,857099,OMZ175,dental caries,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,collagen-binding adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30201780,PubMed,10.1128/JB.00141-18,J Bacteriol. 2018 Nov 6;200(23),jabranches@dental.ufl.edu,Overexpression of vicRKX was associated with decreased rates of intracellular invasion.,L A Alves 2018,2018,5 genes,Alves-2018-CovR and VicRKX regulate transcript,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16001,PHI:10227,UniProt,A0A2J9QDB5,GenBank,PNM00564,,,FDAARGOS_258,vicK,,,,,,,1309,Streptococcus mutans,857099,OMZ175,dental caries,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell wall metabolism sensor histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,30201780,PubMed,10.1128/JB.00141-18,J Bacteriol. 2018 Nov 6;200(23),jabranches@dental.ufl.edu,Overexpression of vicRKX was associated with decreased rates of intracellular invasion.,L A Alves 2018,2018,5 genes,Alves-2018-CovR and VicRKX regulate transcript,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16002,PHI:10228,UniProt,Q93MY4,GenBank,AAK71319,,,NG8,covR,,,,,,,1309,Streptococcus mutans,857099,OMZ175,dental caries,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,responder protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,30201780,PubMed,10.1128/JB.00141-18,J Bacteriol. 2018 Nov 6;200(23),jabranches@dental.ufl.edu,Overexpression of vicRKX was associated with decreased rates of intracellular invasion.,L A Alves 2018,2018,5 genes,Alves-2018-CovR and VicRKX regulate transcript,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16003,PHI:10226,UniProt,B9A8A3,GenBank,BAH16702,,,SA83,Cnm,,,,,,,1309,Streptococcus mutans,857099,OMZ175,dental caries,primates,9606,Homo sapiens (related: human),HCAEC,,,HCAEC cell,collagen-binding adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30201780,PubMed,10.1128/JB.00141-18,J Bacteriol. 2018 Nov 6;200(23),jabranches@dental.ufl.edu,Overexpression of vicRKX was associated with decreased rates of intracellular invasion.,L A Alves 2018,2018,5 genes,Alves-2018-CovR and VicRKX regulate transcript,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16004,PHI:10227,UniProt,A0A2J9QDB5,GenBank,PNM00564,,,FDAARGOS_258,vicK,,,,,,,1309,Streptococcus mutans,857099,OMZ175,dental caries,primates,9606,Homo sapiens (related: human),HCAEC,,,HCAEC cell,cell wall metabolism sensor histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,30201780,PubMed,10.1128/JB.00141-18,J Bacteriol. 2018 Nov 6;200(23),jabranches@dental.ufl.edu,Overexpression of vicRKX was associated with decreased rates of intracellular invasion.,L A Alves 2018,2018,5 genes,Alves-2018-CovR and VicRKX regulate transcript,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16005,PHI:10228,UniProt,Q93MY4,GenBank,AAK71319,,,NG8,covR,,,,,,,1309,Streptococcus mutans,857099,OMZ175,dental caries,primates,9606,Homo sapiens (related: human),HCAEC,,,HCAEC cell,responder protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,30201780,PubMed,10.1128/JB.00141-18,J Bacteriol. 2018 Nov 6;200(23),jabranches@dental.ufl.edu,Overexpression of vicRKX was associated with decreased rates of intracellular invasion.,L A Alves 2018,2018,5 genes,Alves-2018-CovR and VicRKX regulate transcript,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16006,PHI:10229,UniProt,no data found,GenBank,GAW70352,,,HM,vicR,,,,,,PHI:10227; PHI:10230,1309,Streptococcus mutans,857099,OMZ175,dental caries,primates,9606,Homo sapiens (related: human),HCAEC,,,HCAEC cell,two-component response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30201780,PubMed,10.1128/JB.00141-18,J Bacteriol. 2018 Nov 6;200(23),jabranches@dental.ufl.edu,Overexpression of vicRKX was associated with decreased rates of intracellular invasion.,L A Alves 2018,2018,5 genes,Alves-2018-CovR and VicRKX regulate transcript,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16007,PHI:10227,UniProt,A0A2J9QDB5,GenBank,PNM00564,,,FDAARGOS_258,vicK,,,,,,PHI:10229; PHI:10230,1309,Streptococcus mutans,857099,OMZ175,dental caries,primates,9606,Homo sapiens (related: human),HCAEC,,,HCAEC cell,cell wall metabolism sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30201780,PubMed,10.1128/JB.00141-18,J Bacteriol. 2018 Nov 6;200(23),jabranches@dental.ufl.edu,Overexpression of vicRKX was associated with decreased rates of intracellular invasion.,L A Alves 2018,2018,5 genes,Alves-2018-CovR and VicRKX regulate transcript,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16008,PHI:10230,UniProt,no data found,GenBank,AE014984_1,,,UA159,vicX,,,,,,PHI:10229; PHI:10227,1309,Streptococcus mutans,857099,OMZ175,dental caries,primates,9606,Homo sapiens (related: human),HCAEC,,,HCAEC cell,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30201780,PubMed,10.1128/JB.00141-18,J Bacteriol. 2018 Nov 6;200(23),jabranches@dental.ufl.edu,Overexpression of vicRKX was associated with decreased rates of intracellular invasion.,L A Alves 2018,2018,5 genes,Alves-2018-CovR and VicRKX regulate transcript,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16009,PHI:10231,UniProt,Q59X67,GenBank,AOW31479,,,SC5314,EFG1,chromosome R,,,,,PHI:10232,5476,Candida albicans,237561,SC5314,invasive candidiasis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,enhanced filamentous growth protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30037799,PubMed,10.1128/IAI.00415-18,Infect Immun. 2018 Sep 21;86(10),robert.wheeler1@maine.edu,Two hypofilamentous mutants (the efg1Δ/Δ cph1Δ/Δ and eed1Δ/Δ mutants) and a yeast-locked overexpression strain (NRG1OEX) caused disseminated infection with low mortality.,B G Seman 2018,2018,5 genes,Seman-2018-Yeast and filaments have specialize,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16010,PHI:10232,UniProt,P43079,GenBank,AAA59355,,,SC5314,CPH1,,,,,,PHI:10231,5476,Candida albicans,237561,SC5314,invasive candidiasis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30037799,PubMed,10.1128/IAI.00415-18,Infect Immun. 2018 Sep 21;86(10),robert.wheeler1@maine.edu,Two hypofilamentous mutants (the efg1Δ/Δ cph1Δ/Δ and eed1Δ/Δ mutants) and a yeast-locked overexpression strain (NRG1OEX) caused disseminated infection with low mortality.,B G Seman 2018,2018,5 genes,Seman-2018-Yeast and filaments have specialize,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16011,PHI:10233,UniProt,G1UB67,GenBank,AOW31643,,,SC5314,EED1,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,invasive candidiasis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30037799,PubMed,10.1128/IAI.00415-18,Infect Immun. 2018 Sep 21;86(10),robert.wheeler1@maine.edu,Two hypofilamentous mutants (the efg1Δ/Δ cph1Δ/Δ and eed1Δ/Δ mutants) and a yeast-locked overexpression strain (NRG1OEX) caused disseminated infection with low mortality.,B G Seman 2018,2018,5 genes,Seman-2018-Yeast and filaments have specialize,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16012,PHI:10234,UniProt,Q5A0E5,GenBank,AOW30760,,,SC5314,NRG1,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,invasive candidiasis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30037799,PubMed,10.1128/IAI.00415-18,Infect Immun. 2018 Sep 21;86(10),robert.wheeler1@maine.edu,Two hypofilamentous mutants (the efg1Δ/Δ cph1Δ/Δ and eed1Δ/Δ mutants) and a yeast-locked overexpression strain (NRG1OEX) caused disseminated infection with low mortality.,B G Seman 2018,2018,5 genes,Seman-2018-Yeast and filaments have specialize,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16013,PHI:10235,UniProt,Q59MD2,GenBank,AOW26289,,,SC5314,UME6,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,invasive candidiasis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30037799,PubMed,10.1128/IAI.00415-18,Infect Immun. 2018 Sep 21;86(10),robert.wheeler1@maine.edu,Both wild-type-strain and filament-dominant UME6OEX infections produced rapid invasion and mortality but did not spread through the blood.,B G Seman 2018,2018,5 genes,Seman-2018-Yeast and filaments have specialize,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16014,PHI:10236,UniProt,H7C8J5,GenBank,BAL68069,,,NN2193-1,cbm,,,,,,,1309,Streptococcus mutans,,LAR01,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,collagen-binding adhesin,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion full; gene complementation,,,YVS,29524318,PubMed,10.1111/omi.12222,Mol Oral Microbiol. 2018 Jun;33(3):257-269,jlemos@dental.ufl.edu,The mortality rates of G. mellonella larvae infected with the Δcbm strain was significantly lower when compared to the parental LAR01 strain.,A Aviles-Reyes 2018,2018,1 gene,Aviles-Reyes-2018-Whole genome sequence and ph,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16015,PHI:10236,UniProt,H7C8J5,GenBank,BAL68069,,,NN2193-1,cbm,,,,,,,1309,Streptococcus mutans,,LAR01,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HCAEC,,,HCAEC cell,collagen-binding adhesin,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion full; gene complementation,,,YVS,29524318,PubMed,10.1111/omi.12222,Mol Oral Microbiol. 2018 Jun;33(3):257-269,jlemos@dental.ufl.edu,Collagen or laminin binding and HCAECs invasion were drastically reduced in the Δcbm strain.,A Aviles-Reyes 2018,2018,1 gene,Aviles-Reyes-2018-Whole genome sequence and ph,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16016,PHI:10237,UniProt,Q9KIJ3,GenBank,AF232688_3,,,ATCC 25175,SloC,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,primates,9606,Homo sapiens (related: human),,,,saliva,"ABC transporter, substrate binding protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31915219,PubMed,10.1128/mSphere.00764-19,mSphere. 2020 Jan 8;5(1),jlemos@dental.ufl.edu,Disruption of Mn transport resulted in diminished stress tolerance and reduced biofilm formation in the presence of sucrose.,J K Kajfasz 2020,2020,2 genes,"Kajfasz-2020-Manganese Uptake, Mediated by Slo",BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16017,PHI:10238,UniProt,Q8DUX1,GenBank,AE014918_8,,,UA159,MntH,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,primates,9606,Homo sapiens (related: human),,,,saliva,manganese transporter periplasmic protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31915219,PubMed,10.1128/mSphere.00764-19,mSphere. 2020 Jan 8;5(1),jlemos@dental.ufl.edu,Disruption of Mn transport resulted in diminished stress tolerance and reduced biofilm formation in the presence of sucrose.,J K Kajfasz 2020,2020,2 genes,"Kajfasz-2020-Manganese Uptake, Mediated by Slo",BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16018,PHI:10237,UniProt,Q9KIJ3,GenBank,AF232688_3,,,ATCC 25175,SloC,,,,,,PHI:10238,1309,Streptococcus mutans,210007,UA159,infective endocarditis,primates,9606,Homo sapiens (related: human),,,,saliva,"ABC transporter, substrate binding protein",,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31915219,PubMed,10.1128/mSphere.00764-19,mSphere. 2020 Jan 8;5(1),jlemos@dental.ufl.edu,Disruption of Mn transport resulted in diminished stress tolerance and reduced biofilm formation in the presence of sucrose.,J K Kajfasz 2020,2020,2 genes,"Kajfasz-2020-Manganese Uptake, Mediated by Slo",BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16019,PHI:10238,UniProt,Q8DUX1,GenBank,AE014918_8,,,UA159,MntH,,,,,,PHI:10237,1309,Streptococcus mutans,210007,UA159,infective endocarditis,primates,9606,Homo sapiens (related: human),,,,saliva,manganese transporter periplasmic protein,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31915219,PubMed,10.1128/mSphere.00764-19,mSphere. 2020 Jan 8;5(1),jlemos@dental.ufl.edu,Disruption of Mn transport resulted in diminished stress tolerance and reduced biofilm formation in the presence of sucrose.,J K Kajfasz 2020,2020,2 genes,"Kajfasz-2020-Manganese Uptake, Mediated by Slo",BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16020,PHI:10239,UniProt,Q8DT66,GenBank,AE014983_6,,,UA159,rnc,,,,,,,1309,Streptococcus mutans,210007,UA159,sulcal caries,rodents,10114,Rattus (related: rat),Osborne-Mendel,,,tooth,ribonuclease 3,,,exopolysaccharide synthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,27242713,PubMed,10.3389/fmicb.2016.00687,Front Microbiol. 2016 May 10;7:687,hutao@scu.edu.cn,The cariogenecity of S. mutans was decreased by deletion of rnc in a specific pathogen-free (SPF) rat model.,M Y Mao 2016,2016,1 gene,Mao-2016-The rnc Gene Promotes Exopolysacchari,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16021,PHI:10239,UniProt,Q8DT66,GenBank,AE014983_6,,,UA159,rnc,,,,,,,1309,Streptococcus mutans,210007,UA159,sulcal caries,rodents,10114,Rattus (related: rat),Osborne-Mendel,,,tooth,ribonuclease 3,,,exopolysaccharide synthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,27242713,PubMed,10.3389/fmicb.2016.00687,Front Microbiol. 2016 May 10;7:687,hutao@scu.edu.cn,The cariogenecity of S. mutans was decreased by deletion of rnc in a specific pathogen-free (SPF) rat model.,M Y Mao 2016,2016,1 gene,Mao-2016-The rnc Gene Promotes Exopolysacchari,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16022,PHI:10240,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,SaeR,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,infective endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,response regulator SaeR,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31209148,PubMed,10.1128/IAI.00231-19,Infect Immun. 2019 Aug 21;87(9),clee2@uams.edu,There was a direct effect of hla regulation by SaeR on pathogenesis but that the effect depended on the animal model used.,D D Gudeta 2019,2019,2 genes,Gudeta-2019-Contribution of hla regulation by,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16023,PHI:10241,UniProt,P09616,GenBank,CAA25801,,,WOOD 46,hla,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,infective endocarditis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,alpha-hemolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,promoter mutation,,,YVS,31209148,PubMed,10.1128/IAI.00231-19,Infect Immun. 2019 Aug 21;87(9),clee2@uams.edu,There was a direct effect of hla regulation by SaeR on pathogenesis but that the effect depended on the animal model used.,D D Gudeta 2019,2019,2 genes,Gudeta-2019-Contribution of hla regulation by,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16024,PHI:10240,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,SaeR,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,skin infection; soft tissue infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,response regulator SaeR,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31209148,PubMed,10.1128/IAI.00231-19,Infect Immun. 2019 Aug 21;87(9),clee2@uams.edu,There was a direct effect of hla regulation by SaeR on pathogenesis but that the effect depended on the animal model used.,D D Gudeta 2019,2019,2 genes,Gudeta-2019-Contribution of hla regulation by,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16025,PHI:10241,UniProt,P09616,GenBank,CAA25801,,,WOOD 46,hla,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,skin infection; soft tissue infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,heart,alpha-hemolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31209148,PubMed,10.1128/IAI.00231-19,Infect Immun. 2019 Aug 21;87(9),clee2@uams.edu,There was a direct effect of hla regulation by SaeR on pathogenesis but that the effect depended on the animal model used.,D D Gudeta 2019,2019,2 genes,Gudeta-2019-Contribution of hla regulation by,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16026,PHI:10242,UniProt,Q9HZR3,GenBank,AAG06322,,,,cif,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung; bronchoalveolar lavage fluid,CFTR inhibitory factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,28982736,PubMed,10.1152/ajplung.00383.2017,Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L150-L156,dean.madden@dartmouth.edu,Deletion of Cif slowed PA14 inhibition of mucociliary transport (MCT).,K L Hvorecny 2017,2017,1 gene,Hvorecny-2017-An epoxide hydrolase secreted by,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16027,PHI:10243,UniProt,Q51917,GenBank,ARX33819,,,AR_0155,pmpA,,,,,,PHI:10244; PHI:10245,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,F7-2 fimbrial protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16028,PHI:10244,UniProt,no data found,GenBank,,,,,fim8A,,,,,,PHI:10243; PHI:10245,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16029,PHI:10245,UniProt,no data found,GenBank,,,,,fim14A,,,,,,PHI:10243; PHI:10244,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16030,PHI:10243,UniProt,Q51917,GenBank,ARX33819,,,AR_0155,pmpA,,,,,,PHI:10244,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,F7-2 fimbrial protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16031,PHI:10244,UniProt,no data found,GenBank,,,,,fim8A,,,,,,PHI:10243,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16032,PHI:10243,UniProt,Q51917,GenBank,ARX33819,,,AR_0155,pmpA,,,,,,PHI:10245,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,F7-2 fimbrial protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16033,PHI:10245,UniProt,no data found,GenBank,,,,,fim14A,,,,,,PHI:10243,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16034,PHI:10245,UniProt,no data found,GenBank,,,,,fim14A,,,,,,PHI:10244,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16035,PHI:10244,UniProt,no data found,GenBank,,,,,fim8A,,,,,,PHI:10245,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16036,PHI:10243,UniProt,Q51917,GenBank,ARX33819,,,AR_0155,pmpA,,,,,,,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,F7-2 fimbrial protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16037,PHI:10244,UniProt,no data found,GenBank,,,,,fim8A,,,,,,,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16038,PHI:10245,UniProt,no data found,GenBank,,,,,fim14A,,,,,,,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urine; bladder; kidney; spleen,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30082479,PubMed,10.1128/IAI.00388-18,Infect Immun. 2018 Sep 21;86(10),mpears@umich.edu,"MrpJ-regulated fimbrial targets fim8A, fim14A and pmpA contributed to pathogenesis of UTI.",I Debnath 2018,2018,3 genes,Debnath-2018-MrpJ Directly Regulates Proteus m,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16039,PHI:10246,UniProt,Q2YLF3,GenBank,CAJ11756,,,2308,prpA,chromosome I,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,4-hydroxyproline epimerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30126897,PubMed,10.1128/IAI.00402-18,Infect Immun. 2018 Oct 25;86(11),jugalde@iibintech.com.ar,Palmitoylation sites were required for PrpA immunomodulatory activities in vivo.,J M Spera 2018,2018,1 gene,Spera-2018-Brucella hijacks host-mediated palm,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16040,PHI:10246,UniProt,Q2YLF3,GenBank,CAJ11756,,,2308,prpA,chromosome I,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,4-hydroxyproline epimerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,30126897,PubMed,10.1128/IAI.00402-18,Infect Immun. 2018 Oct 25;86(11),jugalde@iibintech.com.ar,Palmitoylation sites were required for PrpA immunomodulatory activities in vivo.,J M Spera 2018,2018,1 gene,Spera-2018-Brucella hijacks host-mediated palm,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16041,PHI:10246,UniProt,Q2YLF3,GenBank,CAJ11756,,,2308,prpA,chromosome I,point mutation changing the cysteine codons (TGC) at positions 8 and 14 of PrpA to serine (AGC),,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,4-hydroxyproline epimerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30126897,PubMed,10.1128/IAI.00402-18,Infect Immun. 2018 Oct 25;86(11),jugalde@iibintech.com.ar,Palmitoylation sites were required for PrpA immunomodulatory activities in vivo.,J M Spera 2018,2018,1 gene,Spera-2018-Brucella hijacks host-mediated palm,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16042,PHI:10246,UniProt,Q2YLF3,GenBank,CAJ11756,,,2308,prpA,chromosome I,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,4-hydroxyproline epimerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30126897,PubMed,10.1128/IAI.00402-18,Infect Immun. 2018 Oct 25;86(11),jugalde@iibintech.com.ar,Palmitoylation sites were required for PrpA immunomodulatory activities in vivo.,J M Spera 2018,2018,1 gene,Spera-2018-Brucella hijacks host-mediated palm,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16043,PHI:10246,UniProt,Q2YLF3,GenBank,CAJ11756,,,2308,prpA,chromosome I,point mutation changing the cysteine codons (TGC) at positions 8 and 14 of PrpA to serine (AGC),,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,4-hydroxyproline epimerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,30126897,PubMed,10.1128/IAI.00402-18,Infect Immun. 2018 Oct 25;86(11),jugalde@iibintech.com.ar,Palmitoylation sites were required for PrpA immunomodulatory activities in vivo.,J M Spera 2018,2018,1 gene,Spera-2018-Brucella hijacks host-mediated palm,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16044,PHI:10247,UniProt,P31778,GenBank,CAB58260,,,GMI1000,hrpB,,,,,,,305,Ralstonia solanacearum,1394180,Rs-09-161,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Agassaim,,,seedling,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30013282,PubMed,10.1007/s12088-018-0736-y,Indian J Microbiol. 2018 Sep;58(3):372-380,trupti_00@yahoo.com,"The mutants were non-pathogenic on its highly susceptible hosts, brinjal and tomato.",T Asolkar 2018,2018,2 genes,Asolkar-2018-Development of T3SS Mutants (hrpB,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16045,PHI:10248,UniProt,P35656,GenBank,CAB58250,,,GMI1000,hrcV,,,,,,,305,Ralstonia solanacearum,1394180,Rs-09-161,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Agassaim,,,seedling,hypersensitivity response secretion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30013282,PubMed,10.1007/s12088-018-0736-y,Indian J Microbiol. 2018 Sep;58(3):372-380,trupti_00@yahoo.com,"The mutants were non-pathogenic on its highly susceptible hosts, brinjal and tomato.",T Asolkar 2018,2018,2 genes,Asolkar-2018-Development of T3SS Mutants (hrpB,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16046,PHI:10247,UniProt,P31778,GenBank,CAB58260,,,GMI1000,hrpB,,,,,,,305,Ralstonia solanacearum,1394180,Rs-09-161,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Pusa Ruby,,,seedling,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30013282,PubMed,10.1007/s12088-018-0736-y,Indian J Microbiol. 2018 Sep;58(3):372-380,trupti_00@yahoo.com,"The mutants were non-pathogenic on its highly susceptible hosts, brinjal and tomato.",T Asolkar 2018,2018,2 genes,Asolkar-2018-Development of T3SS Mutants (hrpB,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16047,PHI:10248,UniProt,P35656,GenBank,CAB58250,,,GMI1000,hrcV,,,,,,,305,Ralstonia solanacearum,1394180,Rs-09-161,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Pusa Ruby,,,seedling,hypersensitivity response secretion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,30013282,PubMed,10.1007/s12088-018-0736-y,Indian J Microbiol. 2018 Sep;58(3):372-380,trupti_00@yahoo.com,"The mutants were non-pathogenic on its highly susceptible hosts, brinjal and tomato.",T Asolkar 2018,2018,2 genes,Asolkar-2018-Development of T3SS Mutants (hrpB,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16048,PHI:10249,UniProt,A0A0C4DHU3,GenBank,KNB06072,,,4287,Fmk1 (FOXG_08140),chromosome 4,,,,,,5507,Fusarium oxysporum,59765,f .sp. lycopersici,wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,seedling; fruit,mitogen-activated protein kinase,,,MAP kinase signalling pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28800849,PubMed,10.1016/j.funbio.2017.05.005,Fungal Biol. 2017 Sep;121(9):775-784,rajam.mv@gmail.com,"Fmk1, Hog1,and Pbs2 silencing led to reduced virulence on tomato seedlings.",M Pareek 2017,2017,3 genes,Pareek-2017-RNAi-mediated silencing of MAP kin,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16049,PHI:10250,UniProt,A0A0D2XQS0,GenBank,KNB04056,,,4287,hog1 (FOXG_06318),chromosome 2a,,,,,,5507,Fusarium oxysporum,59765,f .sp. lycopersici,wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,seedling; fruit,mitogen-activated protein kinase,,,MAP kinase signalling pathway,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28800849,PubMed,10.1016/j.funbio.2017.05.005,Fungal Biol. 2017 Sep;121(9):775-784,rajam.mv@gmail.com,"Fmk1, Hog1,and Pbs2 silencing led to reduced virulence on tomato seedlings.",M Pareek 2017,2017,3 genes,Pareek-2017-RNAi-mediated silencing of MAP kin,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16050,PHI:10251,UniProt,A0A0D2XGR3,GenBank,KNA98914,,,4287,pbs2 (FOXG_03107),chromosome 8,,,,,,5507,Fusarium oxysporum,59765,f .sp. lycopersici,wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,seedling; fruit,STE/STE7 protein kinase,,,MAP kinase signalling pathway,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,28800849,PubMed,10.1016/j.funbio.2017.05.005,Fungal Biol. 2017 Sep;121(9):775-784,rajam.mv@gmail.com,"Fmk1, Hog1,and Pbs2 silencing led to reduced virulence on tomato seedlings.",M Pareek 2017,2017,3 genes,Pareek-2017-RNAi-mediated silencing of MAP kin,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16051,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M3,systemic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,Lancefield group A carbohydrate antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16052,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M28,systemic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,Lancefield group A carbohydrate antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16053,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M1,systemic infection,primates,9606,Homo sapiens (related: human),,,,blood; neutrophil,Lancefield group A carbohydrate antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16054,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M3,systemic infection,primates,9606,Homo sapiens (related: human),,,,blood; neutrophil,Lancefield group A carbohydrate antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16055,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M2,systemic infection,primates,9606,Homo sapiens (related: human),,,,blood,Lancefield group A carbohydrate antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16056,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M4,systemic infection,primates,9606,Homo sapiens (related: human),,,,blood,Lancefield group A carbohydrate antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16057,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M28,systemic infection,primates,9606,Homo sapiens (related: human),,,,blood,Lancefield group A carbohydrate antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16058,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M89,systemic infection,primates,9606,Homo sapiens (related: human),,,,blood,Lancefield group A carbohydrate antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16059,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M2,systemic infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,Lancefield group A carbohydrate antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16060,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M4,systemic infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,Lancefield group A carbohydrate antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16061,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M89,systemic infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,Lancefield group A carbohydrate antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16062,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M28,systemic infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,Lancefield group A carbohydrate antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16063,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M1,systemic infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,serum,Lancefield group A carbohydrate antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16064,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M2,systemic infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,serum,Lancefield group A carbohydrate antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16065,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M3,systemic infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,serum,Lancefield group A carbohydrate antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16066,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M4,systemic infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,serum,Lancefield group A carbohydrate antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16067,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M28,systemic infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,serum,Lancefield group A carbohydrate antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16068,PHI:10252,UniProt,no data found,GenBank,,,,,gacI,,,,,,,1314,Streptococcus pyogenes,,serotype M89,systemic infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),,,,serum,Lancefield group A carbohydrate antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,29382733,PubMed,10.1128/mBio.02294-17,mBio. 2018 Jan 30;9(1),vnizet@ucsd.edu,"GlcNAc side chain of GAC contributed to the innate immune resistance of GAS, but was not a universal prerequisite for virulence in the animal model.",A Henningham 2018,2018,1 gene,Henningham-2018-Virulence Role of the GlcNAc S,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16069,PHI:10253,UniProt,A0A1B7YJY4,GenBank,OBR12214,,,IMI 349063,CHCAP (CH63R_04510),chromosome 3,,,,,,80884,Colletotrichum higginsianum,,CH-1,anthracnose,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,adenylyl cyclase-associated protein,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced; aberrant,,no,NaCl; H2O2; Congo red; calcofluor white (CFW); SDS,NaCl: CHEBI:26710; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,31128679,PubMed,10.1016/j.plantsci.2019.02.012,Plant Sci. 2019 Jun;283:1-10,w-chen@wsu.edu,"Appressorial formation rate, turgor pressure, penetration ability and switch from biotrophic to necrotrophic phases decreased in ΔChCAP mutants.",W Zhu 2019,2019,1 gene,Zhu-2019-The cyclase-associated protein ChCAP,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16070,PHI:10254,UniProt,P69913,GenBank,AAA71919,,,K-12,csrA,,,,,,,562,Escherichia coli,83334,serotype O157:H7,hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelial cell,post-transcriptional regulator,,,flagella biosynthesis,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28870757,PubMed,10.1016/j.resmic.2017.08.003,Res Microbiol. 2017 Oct;168(8):700-709,yangbin@nankai.edu.cn,"Inactivation of CsrA in EHEC O157:H7 resulted in a significant increase in bacterial adherence to host epithelial cells, with a concomitant loss of swimming motility on semi-solid agar plates.",S Wang 2017,2017,1 gene,Wang-2017-Global effect of CsrA on gene expres,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16071,PHI:10254,UniProt,P69913,GenBank,AAA71919,,,K-12,csrA,,,,,,,562,Escherichia coli,83334,serotype O157:H7,hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,post-transcriptional regulator,,,flagella biosynthesis,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,28870757,PubMed,10.1016/j.resmic.2017.08.003,Res Microbiol. 2017 Oct;168(8):700-709,yangbin@nankai.edu.cn,"Inactivation of CsrA in EHEC O157:H7 resulted in a significant increase in bacterial adherence to host epithelial cells, with a concomitant loss of swimming motility on semi-solid agar plates.",S Wang 2017,2017,1 gene,Wang-2017-Global effect of CsrA on gene expres,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16072,PHI:10254,UniProt,P69913,GenBank,AAA71919,,,K-12,csrA,,,,,,,562,Escherichia coli,83334,serotype O157:H7,hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelial cell,post-transcriptional regulator,,,flagella biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28870757,PubMed,10.1016/j.resmic.2017.08.003,Res Microbiol. 2017 Oct;168(8):700-709,yangbin@nankai.edu.cn,"Inactivation of CsrA in EHEC O157:H7 resulted in a significant increase in bacterial adherence to host epithelial cells, with a concomitant loss of swimming motility on semi-solid agar plates.",S Wang 2017,2017,1 gene,Wang-2017-Global effect of CsrA on gene expres,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16073,PHI:10254,UniProt,P69913,GenBank,AAA71919,,,K-12,csrA,,,,,,,562,Escherichia coli,83334,serotype O157:H7,hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,post-transcriptional regulator,,,flagella biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,28870757,PubMed,10.1016/j.resmic.2017.08.003,Res Microbiol. 2017 Oct;168(8):700-709,yangbin@nankai.edu.cn,"Inactivation of CsrA in EHEC O157:H7 resulted in a significant increase in bacterial adherence to host epithelial cells, with a concomitant loss of swimming motility on semi-solid agar plates.",S Wang 2017,2017,1 gene,Wang-2017-Global effect of CsrA on gene expres,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16074,PHI:10255,UniProt,A0A0N9DQW5,GenBank,ALF05564,,,,VmXyl1,,,,,,,105487,Valsa mali,,LXS080601,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; stem,"endo-beta-1,4-xylanase",,,,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29868105,PubMed,10.3389/fpls.2018.00663,Front Plant Sci. 2018 May 17;9:663,cxwang@qau.edu.cn,"The deletion of VmXyl1 did not affect mycelia growth; however, it significantly reduced pycnidia formation in V. mali.",C Yu 2018,2018,1 gene,"Yu-2018-Deletion of Endo-beta-1,4-Xylanase VmX",BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16075,PHI:10256,UniProt,T4N9Q8,GenBank,EQJ51999,,,P28,PrkC,,,,,,,1496,Clostridioides difficile,,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,gut,ser/Thr kinase,,,,unaffected pathogenicity,,,,,,wild type,,aberrant,,no,vancomycin; teicoplanin; amoxicillin; imipenem; cefoxitin; ceftazidime; cefepime; cefotaxime; polymyxin B; bacitracin; nisin,vancomycin: CHEBI:28001; teicoplanin: CHEBI:29687; amoxicillin: CHEBI:2676; imipenem: CHEBI:471744; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefepime: CHEBI:478164; cefotaxime: CHEBI:204928; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669; nisin: CHEBI:71629,,,,,gene deletion: full; gene complementation,,,YVS,31085703,PubMed,10.1128/IAI.00005-19,Infect Immun. 2019 Jul 23;87(8),isabelle.martin-verstraete@pasteur.fr,ΔPrkC mutant was less motile and formed more biofilm.,E Cuenot 2019,2019,1 gene,Cuenot-2019-The Ser_Thr kinase PrkC participat,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16076,PHI:10257,UniProt,Q8DVB6,GenBank,AAN58318,,,UA159,lytS,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10114,Rattus (related: rat),Wistar,,,blood,sensor protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31143407,PubMed,10.1080/20002297.2019.1607505,J Oral Microbiol. 2019 May 9;11(1):1607505,mklein@foar.unesp.br,Inactivation of lytST and dltAD impaired S. mutans cariogenicity and virulence in vivo.,M C Castillo Pedraza 2019,2019,5 genes,Castillo Pedraz-2019-Inactivation of Streptoco,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16077,PHI:10258,UniProt,no data found,GenBank,,,,,lytT,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10114,Rattus (related: rat),Wistar,,,blood,response regulator,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31143407,PubMed,10.1080/20002297.2019.1607505,J Oral Microbiol. 2019 May 9;11(1):1607505,mklein@foar.unesp.br,Inactivation of lytST and dltAD impaired S. mutans cariogenicity and virulence in vivo.,M C Castillo Pedraza 2019,2019,5 genes,Castillo Pedraz-2019-Inactivation of Streptoco,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16078,PHI:10259,UniProt,A0A2J9QCW3,GenBank,PNM00420,,,FDAARGOS_258,dltA,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10114,Rattus (related: rat),Wistar,,,blood,D-alanine--poly(phosphoribitol) ligase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31143407,PubMed,10.1080/20002297.2019.1607505,J Oral Microbiol. 2019 May 9;11(1):1607505,mklein@foar.unesp.br,Inactivation of lytST and dltAD impaired S. mutans cariogenicity and virulence in vivo.,M C Castillo Pedraza 2019,2019,5 genes,Castillo Pedraz-2019-Inactivation of Streptoco,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16079,PHI:10260,UniProt,O68578,GenBank,AAC05777,,,LT11,dltD,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10114,Rattus (related: rat),Wistar,,,blood,extramembranal protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31143407,PubMed,10.1080/20002297.2019.1607505,J Oral Microbiol. 2019 May 9;11(1):1607505,mklein@foar.unesp.br,Inactivation of lytST and dltAD impaired S. mutans cariogenicity and virulence in vivo.,M C Castillo Pedraza 2019,2019,5 genes,Castillo Pedraz-2019-Inactivation of Streptoco,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16080,PHI:10261,UniProt,M4JBX5,GenBank,AGC00466,,,LT11,gtfB,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10114,Rattus (related: rat),Wistar,,,blood,glucosyltransferase-I,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31143407,PubMed,10.1080/20002297.2019.1607505,J Oral Microbiol. 2019 May 9;11(1):1607505,mklein@foar.unesp.br,Inactivation of lytST and dltAD impaired S. mutans cariogenicity and virulence in vivo.,M C Castillo Pedraza 2019,2019,5 genes,Castillo Pedraz-2019-Inactivation of Streptoco,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16081,PHI:10257,UniProt,Q8DVB6,GenBank,AAN58318,,,UA159,lytS,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,moths,7137,Galleria mellonella (related: greater wax moth),Wistar,,,larva,sensor protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31143407,PubMed,10.1080/20002297.2019.1607505,J Oral Microbiol. 2019 May 9;11(1):1607505,mklein@foar.unesp.br,Inactivation of lytST and dltAD impaired S. mutans cariogenicity and virulence in vivo.,M C Castillo Pedraza 2019,2019,5 genes,Castillo Pedraz-2019-Inactivation of Streptoco,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16082,PHI:10258,UniProt,no data found,GenBank,,,,,lytT,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,moths,7137,Galleria mellonella (related: greater wax moth),Wistar,,,larva,response regulator,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31143407,PubMed,10.1080/20002297.2019.1607505,J Oral Microbiol. 2019 May 9;11(1):1607505,mklein@foar.unesp.br,Inactivation of lytST and dltAD impaired S. mutans cariogenicity and virulence in vivo.,M C Castillo Pedraza 2019,2019,5 genes,Castillo Pedraz-2019-Inactivation of Streptoco,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16083,PHI:10259,UniProt,A0A2J9QCW3,GenBank,PNM00420,,,FDAARGOS_258,dltA,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,moths,7137,Galleria mellonella (related: greater wax moth),Wistar,,,larva,D-alanine--poly(phosphoribitol) ligase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31143407,PubMed,10.1080/20002297.2019.1607505,J Oral Microbiol. 2019 May 9;11(1):1607505,mklein@foar.unesp.br,Inactivation of lytST and dltAD impaired S. mutans cariogenicity and virulence in vivo.,M C Castillo Pedraza 2019,2019,5 genes,Castillo Pedraz-2019-Inactivation of Streptoco,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16084,PHI:10260,UniProt,O68578,GenBank,AAC05777,,,LT11,dltD,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,moths,7137,Galleria mellonella (related: greater wax moth),Wistar,,,larva,extramembranal protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31143407,PubMed,10.1080/20002297.2019.1607505,J Oral Microbiol. 2019 May 9;11(1):1607505,mklein@foar.unesp.br,Inactivation of lytST and dltAD impaired S. mutans cariogenicity and virulence in vivo.,M C Castillo Pedraza 2019,2019,5 genes,Castillo Pedraz-2019-Inactivation of Streptoco,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16085,PHI:10261,UniProt,M4JBX5,GenBank,AGC00466,,,LT11,gtfB,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,moths,7137,Galleria mellonella (related: greater wax moth),Wistar,,,larva,glucosyltransferase-I,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,31143407,PubMed,10.1080/20002297.2019.1607505,J Oral Microbiol. 2019 May 9;11(1):1607505,mklein@foar.unesp.br,Inactivation of lytST and dltAD impaired S. mutans cariogenicity and virulence in vivo.,M C Castillo Pedraza 2019,2019,5 genes,Castillo Pedraz-2019-Inactivation of Streptoco,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16086,PHI:10262,UniProt,E9ERE3,GenBank,EFZ01310,,,ARSEF 23,Mras1 (MAA_02539),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,fungal infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell surface protein,,,,reduced virulence,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30967021,PubMed,10.1098/rstb.2018.0321,Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180321,cswang@sibs.ac.cn,Insect bioassays revealed that the virulence of most null mutants were significantly impaired during topical infection but not during injection of insects.,W Huang 2019,2019,8 genes,Huang-2019-Unveiling the function and regulati,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16087,PHI:10263,UniProt,E9F7P0,GenBank,EFY96178,,,ARSEF 23,Mras2 (MAA_08289),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,fungal infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell surface protein,,,,reduced virulence,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30967021,PubMed,10.1098/rstb.2018.0321,Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180321,cswang@sibs.ac.cn,Insect bioassays revealed that the virulence of most null mutants were significantly impaired during topical infection but not during injection of insects.,W Huang 2019,2019,8 genes,Huang-2019-Unveiling the function and regulati,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16088,PHI:10264,UniProt,E9F453,GenBank,EFY97410,,,ARSEF 23,Mras3 (MAA_07052),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,fungal infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell surface protein,,,,reduced virulence,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30967021,PubMed,10.1098/rstb.2018.0321,Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180321,cswang@sibs.ac.cn,Insect bioassays revealed that the virulence of most null mutants were significantly impaired during topical infection but not during injection of insects.,W Huang 2019,2019,8 genes,Huang-2019-Unveiling the function and regulati,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16089,PHI:10265,UniProt,E9ESD4,GenBank,EFZ01651,,,ARSEF 23,Mras4 (MAA_02880),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,fungal infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,uncharacterized protein,,,,reduced virulence,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30967021,PubMed,10.1098/rstb.2018.0321,Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180321,cswang@sibs.ac.cn,Insect bioassays revealed that the virulence of most null mutants were significantly impaired during topical infection but not during injection of insects.,W Huang 2019,2019,8 genes,Huang-2019-Unveiling the function and regulati,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16090,PHI:10266,UniProt,E9EYL2,GenBank,EFY99053,,,ARSEF 23,Mras5 (MAA_05111),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,fungal infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"CND1, Gas1-like protein",,,,reduced virulence,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30967021,PubMed,10.1098/rstb.2018.0321,Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180321,cswang@sibs.ac.cn,Insect bioassays revealed that the virulence of most null mutants were significantly impaired during topical infection but not during injection of insects.,W Huang 2019,2019,8 genes,Huang-2019-Unveiling the function and regulati,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16091,PHI:10267,UniProt,E9F5F3,GenBank,EFY96956,,,ARSEF 23,Mras6 (MAA_07502),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,fungal infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,uncharacterized protein,,,,reduced virulence,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30967021,PubMed,10.1098/rstb.2018.0321,Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180321,cswang@sibs.ac.cn,Insect bioassays revealed that the virulence of most null mutants were significantly impaired during topical infection but not during injection of insects.,W Huang 2019,2019,8 genes,Huang-2019-Unveiling the function and regulati,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16092,PHI:10268,UniProt,E9EYX4,GenBank,EFY99165,,,ARSEF 23,Mras7 (MAA_05223),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,fungal infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,CAS1 protein,,,,reduced virulence,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,30967021,PubMed,10.1098/rstb.2018.0321,Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180321,cswang@sibs.ac.cn,Insect bioassays revealed that the virulence of most null mutants were significantly impaired during topical infection but not during injection of insects.,W Huang 2019,2019,8 genes,Huang-2019-Unveiling the function and regulati,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16093,PHI:10269,UniProt,E9F0Y0,GenBank,EFY98790,,,ARSEF 23,Mrst12 (MAA_05929),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,fungal infection,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,transcription factor,,,,reduced virulence,,yes,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30967021,PubMed,10.1098/rstb.2018.0321,Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180321,cswang@sibs.ac.cn,Insect bioassays revealed that the virulence of most null mutants were significantly impaired during topical infection but not during injection of insects.,W Huang 2019,2019,8 genes,Huang-2019-Unveiling the function and regulati,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16094,PHI:10270,UniProt,Q8UID9,GenBank,AAK86175,,,ATCC 33970,ybeY (atu0358),circular,,,,,,358,Agrobacterium tumefaciens,,C58,tumor,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,endoribonuclease,,,,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30885931,PubMed,10.1128/JB.00730-18,J Bacteriol. 2019 May 8;201(11),franz.narberhaus@rub.de,"Deletion of ybeY alone resulted in a less pronounced growth defect and the ΔhfqΔybeY double mutant exhibited the most severe growth defect, which could be rescued by ectopically expressed hfq or ybeY from A. tumefaciens.",P Moller 2019,2019,2 genes,Moller-2019-The RNase YbeY is vital for riboso,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16095,PHI:10271,UniProt,F7UA14,GenBank,EGP57160,,,F2,hfq,C,,,,,,358,Agrobacterium tumefaciens,,C58,tumor,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,RNA-binding protein,,,,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30885931,PubMed,10.1128/JB.00730-18,J Bacteriol. 2019 May 8;201(11),franz.narberhaus@rub.de,"Deletion of ybeY alone resulted in a less pronounced growth defect and the ΔhfqΔybeY double mutant exhibited the most severe growth defect, which could be rescued by ectopically expressed hfq or ybeY from A. tumefaciens.",P Moller 2019,2019,2 genes,Moller-2019-The RNase YbeY is vital for riboso,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16096,PHI:10270,UniProt,Q8UID9,GenBank,AAK86175,,,ATCC 33970,ybeY (atu0358),circular,,,,,,358,Agrobacterium tumefaciens,,C58,tumor,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling; root,endoribonuclease,,,,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30885931,PubMed,10.1128/JB.00730-18,J Bacteriol. 2019 May 8;201(11),franz.narberhaus@rub.de,"Deletion of ybeY alone resulted in a less pronounced growth defect and the ΔhfqΔybeY double mutant exhibited the most severe growth defect, which could be rescued by ectopically expressed hfq or ybeY from A. tumefaciens.",P Moller 2019,2019,2 genes,Moller-2019-The RNase YbeY is vital for riboso,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16097,PHI:10271,UniProt,F7UA14,GenBank,EGP57160,,,F2,hfq,C,,,,,,358,Agrobacterium tumefaciens,,C58,tumor,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling; root,RNA-binding protein,,,,reduced virulence,,,,,,wild type,,reduced,,no,,,,,,,gene deletion: full,,,YVS,30885931,PubMed,10.1128/JB.00730-18,J Bacteriol. 2019 May 8;201(11),franz.narberhaus@rub.de,"Deletion of ybeY alone resulted in a less pronounced growth defect and the ΔhfqΔybeY double mutant exhibited the most severe growth defect, which could be rescued by ectopically expressed hfq or ybeY from A. tumefaciens.",P Moller 2019,2019,2 genes,Moller-2019-The RNase YbeY is vital for riboso,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16098,PHI:10272,UniProt,E5A7E1,GenBank,CBX99536,,,,abl1 (Lema_T087750.1),,,,,,,5022,Leptosphaeria maculans,,D5,blackleg (rapeseed),eudicots,3708,Brassica napus (related: rape),cv. Westar,,,cotyledon,cytochrome P450 monooxygenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31034868,PubMed,10.1016/j.fgb.2019.04.015,Fungal Genet Biol. 2019 Sep;130:62-71,alexander.idnurm@unimelb.edu.au,The abl1 and pks5 genes were not required for pathogenicity on B.napus cotyledons.,R Darma 2019,2019,2 genes,Darma-2019-Identification of a gene cluster fo,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16099,PHI:10273,UniProt,E5A7D9,GenBank,CBX99534,,,,pks5 (Lema_T087730.1),,,,,,,5022,Leptosphaeria maculans,,D5,blackleg (rapeseed),eudicots,3708,Brassica napus (related: rape),cv. Westar,,,cotyledon,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31034868,PubMed,10.1016/j.fgb.2019.04.015,Fungal Genet Biol. 2019 Sep;130:62-71,alexander.idnurm@unimelb.edu.au,The abl1 and pks5 genes were not required for pathogenicity on B.napus cotyledons.,R Darma 2019,2019,2 genes,Darma-2019-Identification of a gene cluster fo,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16100,PHI:10274,UniProt,W8U4X9,GenBank,AHM68836,,,502A,qoxD,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,quinol oxidase subunit 4,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16101,PHI:10275,UniProt,A0A390C306,GenBank,AHM68850,,,502A,menD,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16102,PHI:10276,UniProt,A0A2Y2A0B5,GenBank,AHM70338,,,502A,murA,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,UDP-N-acetylglucosamine 1-carboxyvinyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16103,PHI:10277,UniProt,W8US24,GenBank,AHM68945,,,502A,ndhC,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,NADH dehydrogenase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16104,PHI:10278,UniProt,W8U6D4,GenBank,AHM69351,,,502A,purR,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,purine operon repressor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16105,PHI:10279,UniProt,no data found,GenBank,AHM70948,,,502A,ebh,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,matrix-binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16106,PHI:10280,UniProt,no data found,GenBank,AHM69286,,,502A,sdrC,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,hydrolase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16107,PHI:10281,UniProt,W8TUA3,GenBank,AHM70189,,,502A,unnamedB,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,hypothetical membrane protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16108,PHI:10278,UniProt,W8U6D4,GenBank,AHM69351,,,502A,purR,,,,,,PHI:10282,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,purine operon repressor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16109,PHI:10282,UniProt,W8TRT9,GenBank,AHM69299,,,502A,tufA,,Ala271Val,,,,PHI:10278,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,elongation factor Tu,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16110,PHI:10282,UniProt,W8TRT9,GenBank,AHM69299,,,502A,tufA,,Ala271Val,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,elongation factor Tu,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16111,PHI:10283,UniProt,no data found,GenBank,AHM69226,,,502A,mnhA,,Ala722Thr,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,monovalent cation/H+ antiporter subunit A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16112,PHI:10284,UniProt,A0A390LLR3,GenBank,AHM68851,,,502A,menF,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,isochorismate synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16113,PHI:10285,UniProt,W8TTB7,GenBank,AHM70893,,,502A,srrA,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16114,PHI:10286,UniProt,A0A3M8WT54,GenBank,AHM69943,,,502A,ypfH,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,carboxylesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16115,PHI:10287,UniProt,A0A3A5M417,GenBank,AHM70790,,,502A,aroE,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,shikimate dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16116,PHI:10288,UniProt,H9BRP9,GenBank,AHM69145,,,502A,saeS,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16117,PHI:10289,UniProt,Q9X668,GenBank,AHM69205,,,502A,nupC,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,nucleoside permease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16118,PHI:10290,UniProt,W8UWD7,GenBank,AHM70475,,,502A,yhcF,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,GntR family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16119,PHI:10291,UniProt,A0A0C6DRX4,GenBank,AHM68983,,,502A,unnamed A,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,hypothetical peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16120,PHI:10292,UniProt,W8TWD5,GenBank,AHM70974,,,502A,brnQ2,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,branched-chain amino acid ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16121,PHI:10293,UniProt,W8U4S5,GenBank,AHM68781,,,502A,ctaB,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,protoheme IX farnesyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16122,PHI:10294,UniProt,W8TW76,GenBank,AHM70914,,,502A,ubiE,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,ubiquinone biosynthesis methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene disruption; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16123,PHI:10292,UniProt,W8U4S5,GenBank,AHM68781,,,502A,ctaB,,Thr222Ile,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,protoheme IX farnesyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16124,PHI:10287,UniProt,A0A3A5M417,GenBank,AHM70790,,,502A,aroE,,Thr182Ile,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,shikimate dehydrogenase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16125,PHI:10288,UniProt,H9BRP9,GenBank,AHM69145,,,502A,saeS,,Ala106Thr,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16126,PHI:10291,UniProt,A0A0C6DRX4,GenBank,AHM68983,,,502A,unnamed A,,Asp486Glu,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,hypothetical peptidase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16127,PHI:10290,UniProt,W8UWD7,GenBank,AHM70475,,,502A,yhcF,,Thr74Ile,,,,,1280,Staphylococcus aureus,,ATCC 29213,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,GntR family transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,30642903,PubMed,10.1128/IAI.00884-18,Infect Immun. 2019 Mar 25;87(4),stevesal@uw.edu,Directed inactivating lesions identified loss-of-function mutations that contributed to pathogenicity phenotypes.,K McLean 2019,2019,21 genes,McLean-2019-Artificial selection for pathogeni,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16128,PHI:10295,UniProt,A0A194WD70,GenBank,KUI74297,,,03–8,Gvm2 (VM1G_09956),chromosome 12,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; stem,guanine nucleotide-binding protein alpha-2 subunit,,,,reduced virulence,,,,,,reduced,,wild type,,no,NaCl; H2O2; SDS,NaCl: CHEBI:26710; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28267786,PubMed,10.1371/journal.pone.0173141,PLoS One. 2017 Mar 7;12(3):e0173141,huanglili@nwsuaf.edu.cn,"Gvm2 and Gvm3 seem to be involved in asexual reproduction, and mutants were hypersensitive to oxidative and cell membrane stresses.",N Song 2017,2017,2 genes,Song-2017-Galpha proteins Gvm2 and Gvm3 regula,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16129,PHI:10296,UniProt,A0A194VWI2,GenBank,KUI68175,,,03–8,Gvm3 (VM1G_04248),chromosome 4,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; stem,guanine nucleotide-binding protein alpha-3 subunit,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; H2O2; SDS,NaCl: CHEBI:26710; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,28267786,PubMed,10.1371/journal.pone.0173141,PLoS One. 2017 Mar 7;12(3):e0173141,huanglili@nwsuaf.edu.cn,"Gvm2 and Gvm3 seem to be involved in asexual reproduction, and mutants were hypersensitive to oxidative and cell membrane stresses.",N Song 2017,2017,2 genes,Song-2017-Galpha proteins Gvm2 and Gvm3 regula,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16130,PHI:10297,UniProt,no data found,GenBank,,,,,pinT,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,intestinal epithelium,PhoPQ-activated sRNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31262841,PubMed,10.1128/JB.00312-19,J Bacteriol. 2019 Sep 6;201(19),slauch@illinois.edu,PinT controled a series of virulence genes at the posttranscriptional level in order to adapt Salmonella from the invasion stage to intracellular survival.,K Kim 2019,2019,2 genes,Kim-2019-The sRNA PinT contributes to PhoP-med,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16131,PHI:10297,UniProt,no data found,GenBank,,,,,pinT,,,,,,PHI:10298,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,intestinal epithelium,PhoPQ-activated sRNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31262841,PubMed,10.1128/JB.00312-19,J Bacteriol. 2019 Sep 6;201(19),slauch@illinois.edu,PinT controled a series of virulence genes at the posttranscriptional level in order to adapt Salmonella from the invasion stage to intracellular survival.,K Kim 2019,2019,2 genes,Kim-2019-The sRNA PinT contributes to PhoP-med,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16132,PHI:10298,UniProt,no data found,GenBank,,,,,spi1,,,,,,PHI:10297,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,intestinal epithelium,Salmonella pathogenicity island 1 (SPI1) type III secretion system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31262841,PubMed,10.1128/JB.00312-19,J Bacteriol. 2019 Sep 6;201(19),slauch@illinois.edu,PinT controled a series of virulence genes at the posttranscriptional level in order to adapt Salmonella from the invasion stage to intracellular survival.,K Kim 2019,2019,2 genes,Kim-2019-The sRNA PinT contributes to PhoP-med,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16133,PHI:10297,UniProt,no data found,GenBank,,,,,pinT,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,PhoPQ-activated sRNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31262841,PubMed,10.1128/JB.00312-19,J Bacteriol. 2019 Sep 6;201(19),slauch@illinois.edu,PinT controled a series of virulence genes at the posttranscriptional level in order to adapt Salmonella from the invasion stage to intracellular survival.,K Kim 2019,2019,2 genes,Kim-2019-The sRNA PinT contributes to PhoP-med,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16134,PHI:10297,UniProt,no data found,GenBank,,,,,pinT,,,,,,PHI:10298,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,PhoPQ-activated sRNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31262841,PubMed,10.1128/JB.00312-19,J Bacteriol. 2019 Sep 6;201(19),slauch@illinois.edu,PinT controled a series of virulence genes at the posttranscriptional level in order to adapt Salmonella from the invasion stage to intracellular survival.,K Kim 2019,2019,2 genes,Kim-2019-The sRNA PinT contributes to PhoP-med,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16135,PHI:10298,UniProt,no data found,GenBank,,,,,spi1,,,,,,PHI:10297,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,Salmonella pathogenicity island 1 (SPI1) type III secretion system,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,31262841,PubMed,10.1128/JB.00312-19,J Bacteriol. 2019 Sep 6;201(19),slauch@illinois.edu,PinT controled a series of virulence genes at the posttranscriptional level in order to adapt Salmonella from the invasion stage to intracellular survival.,K Kim 2019,2019,2 genes,Kim-2019-The sRNA PinT contributes to PhoP-med,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16136,PHI:10299,UniProt,P42383,GenBank,CAA52062,,,CCUG 17874,HpHSP60,,,,,,,210,Helicobacter pylori,,,gastric infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,stomach,heat shock protein 60,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,YVS,29660522,PubMed,10.1016/j.micpath.2018.04.016,Microb Pathog. 2018 Jun;119:152-161,liaonms@mail.nctu.edu.tw,The results indicate that chronic H. pylori infection was correlated with HpHSP60 and that the blockage of HpHSP60 could decrease H.pylori colonization and the generation of Treg cells.,W T Hsu 2018,2018,1 gene,Hsu-2018-Helicobacter pylori-derived heat shoc,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16137,PHI:10299,UniProt,P42383,GenBank,CAA52062,,,CCUG 17874,HpHSP60,,,,,,,210,Helicobacter pylori,,,gastric infection,primates,9606,Homo sapiens (related: human),PBMC,,,peripheral blood mononuclear cell,heat shock protein 60,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,YVS,29660522,PubMed,10.1016/j.micpath.2018.04.016,Microb Pathog. 2018 Jun;119:152-161,liaonms@mail.nctu.edu.tw,The results indicate that chronic H. pylori infection was correlated with HpHSP60 and that the blockage of HpHSP60 could decrease H.pylori colonization and the generation of Treg cells.,W T Hsu 2018,2018,1 gene,Hsu-2018-Helicobacter pylori-derived heat shoc,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16138,PHI:10299,UniProt,P42383,GenBank,CAA52062,,,CCUG 17874,HpHSP60,,,,,,,210,Helicobacter pylori,,,gastric infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,heat shock protein 60,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,YVS,29660522,PubMed,10.1016/j.micpath.2018.04.016,Microb Pathog. 2018 Jun;119:152-161,liaonms@mail.nctu.edu.tw,The results indicate that chronic H. pylori infection was correlated with HpHSP60 and that the blockage of HpHSP60 could decrease H.pylori colonization and the generation of Treg cells.,W T Hsu 2018,2018,1 gene,Hsu-2018-Helicobacter pylori-derived heat shoc,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16139,PHI:10300,UniProt,A0Q7I0,GenBank,ABK90195,,,U112,pdpC,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30057173,PubMed,10.1016/j.chom.2018.07.003,Cell Host Microbe. 2018 Aug 8;24(2):285-295.e8,mougous@uw.edu,Deletion of opiA further diminished the in vivo growth of F.novicida ΔpdpC and led to an additional decrease in morbidity compared with that exhibited by mice infected with F. novicida ΔpdpC.,H E Ledvina 2018,2018,2 genes,Ledvina-2018-A Phosphatidylinositol 3-Kinase E,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16140,PHI:10300,UniProt,A0Q7I0,GenBank,ABK90195,,,U112,pdpC,,,,,,PHI:10301,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,30057173,PubMed,10.1016/j.chom.2018.07.003,Cell Host Microbe. 2018 Aug 8;24(2):285-295.e8,mougous@uw.edu,Deletion of opiA further diminished the in vivo growth of F.novicida ΔpdpC and led to an additional decrease in morbidity compared with that exhibited by mice infected with F. novicida ΔpdpC.,H E Ledvina 2018,2018,2 genes,Ledvina-2018-A Phosphatidylinositol 3-Kinase E,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16141,PHI:10301,UniProt,no data found,GenBank,,,,,opiA,,,,,,PHI:10300,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,"outside pathogenicity island A (OpiA), a family of wortmannin-resistant bacterial phosphatidylinositol (PI)3-kinase enzymes",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,30057173,PubMed,10.1016/j.chom.2018.07.003,Cell Host Microbe. 2018 Aug 8;24(2):285-295.e8,mougous@uw.edu,Deletion of opiA further diminished the in vivo growth of F.novicida ΔpdpC and led to an additional decrease in morbidity compared with that exhibited by mice infected with F. novicida ΔpdpC.,H E Ledvina 2018,2018,2 genes,Ledvina-2018-A Phosphatidylinositol 3-Kinase E,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16142,PHI:10302,UniProt,no data found,GenBank,,,,,PSR2,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,30595554,PubMed,10.1016/j.chom.2018.11.007,Cell Host Microbe. 2019 Jan 9;25(1):153-165.e5,wenbo.ma@ucr.edu,Phytophthora effector PSR2 specifically inhibited secondary siRNA biogenesis in Arabidopsis and promoted infection.,Y Hou 2019,2019,1 gene,Hou-2019-A Phytophthora Effector Suppresses Tr,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16143,PHI:10303,UniProt,Q9PL71,GenBank,AAF39108,,,Nigg,tc0237,,,,,,,83560,Chlamydia muridarum,1434769,Nigg3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,stomach; small intestine; duodenum; jejunum; ileum; large intestine; cecum; colon; rectum,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31160366,PubMed,10.1128/IAI.00265-19,Infect Immun. 2019 Jul 23;87(8),Zhongg@UTHSCSA.EDU,The chromosomal mutant was rapidly cleared from the colon while the plasmid mutant was able to continuously colonize the colon following an intracolonic inoculation.,J J Koprivsek 2019,2019,3 genes,Koprivsek-2019-Distinct roles of chromosome- v,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16144,PHI:10304,UniProt,Q9PK05,GenBank,AAF39490,,,Nigg,tc0668,,,,,,,83560,Chlamydia muridarum,1434769,Nigg3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,stomach; small intestine; duodenum; jejunum; ileum; large intestine; cecum; colon; rectum,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31160366,PubMed,10.1128/IAI.00265-19,Infect Immun. 2019 Jul 23;87(8),Zhongg@UTHSCSA.EDU,The chromosomal mutant was rapidly cleared from the colon while the plasmid mutant was able to continuously colonize the colon following an intracolonic inoculation.,J J Koprivsek 2019,2019,3 genes,Koprivsek-2019-Distinct roles of chromosome- v,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16145,PHI:10305,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,pgp3,,,,,,,83560,Chlamydia muridarum,1434769,Nigg3,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,stomach; small intestine; duodenum; jejunum; ileum; large intestine; cecum; colon; rectum,virulence plasmid protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31160366,PubMed,10.1128/IAI.00265-19,Infect Immun. 2019 Jul 23;87(8),Zhongg@UTHSCSA.EDU,The chromosomal mutant was rapidly cleared from the colon while the plasmid mutant was able to continuously colonize the colon following an intracolonic inoculation.,J J Koprivsek 2019,2019,3 genes,Koprivsek-2019-Distinct roles of chromosome- v,BATCH_100B,2020-05-01,MC,,,,,,,,,,,,,
,,Record 16146,PHI:10306,UniProt,O54081,GenBank,CAA73667,,,Newman,lukE,,,,,,PHI:10307,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,leukotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16147,PHI:10307,UniProt,O54082,GenBank,CAA73668,,,Newman,lukD,,,,,,PHI:10306,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,leukotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16148,PHI:10308,UniProt,P0A074,GenBank,AAA26637,,,,hlgA,,,,,,PHI:10309; PHI:10310,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,gamma-hemolysin component A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16149,PHI:10309,UniProt,Q07227,GenBank,AAA26638,,,,hlgC,,,,,,PHI:10308; PHI:10310,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,gamma-hemolysin component C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16150,PHI:10310,UniProt,P0A077,GenBank,AAA26639,,,,hlgB,,,,,,PHI:10308; PHI:10309,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,gamma-hemolysin component A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16151,PHI:10306,UniProt,O54081,GenBank,CAA73667,,,Newman,lukE,,,,,,PHI:10307; PHI:10308; PHI:10309; PHI:10310,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,leukotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16152,PHI:10307,UniProt,O54082,GenBank,CAA73668,,,Newman,lukD,,,,,,PHI:10306; PHI:10308; PHI:10309; PHI:10310,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,leukotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16153,PHI:10308,UniProt,P0A074,GenBank,AAA26637,,,,hlgA,,,,,,PHI:10306; PHI:10307; PHI:10309; PHI:10310,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,gamma-hemolysin component A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16154,PHI:10309,UniProt,Q07227,GenBank,AAA26638,,,,hlgC,,,,,,PHI:10306; PHI:10307; PHI:10308; PHI:10310,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,gamma-hemolysin component C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16155,PHI:10310,UniProt,P0A077,GenBank,AAA26639,,,,hlgB,,,,,,PHI:10306; PHI:10307; PHI:10308; PHI:10309,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,gamma-hemolysin component A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16156,PHI:10306,UniProt,O54081,GenBank,CAA73667,,,Newman,lukE,,,,,,PHI:10307,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,leukotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16157,PHI:10307,UniProt,O54082,GenBank,CAA73668,,,Newman,lukD,,,,,,PHI:10306,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,heart; kidney,leukotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30799265,PubMed,10.1016/j.chom.2019.01.015,Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9,victor.torres@nyulangone.org,"Neither LukED nor HlgAB deficiency alleviated S. aureus burdens in the tissues examined, suggesting that the toxins directly mediated lethality, instead of indirectly by increasing bacterial burden.",A Lubkin 2019,2019,5 genes,Lubkin-2019-Staphylococcus aureus Leukocidins,BATCH_100C,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16158,PHI:10311,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,S1407P,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,adenylate cyclase,,,,reduced virulence,,,,,,aberrant,,reduced,reduced,no,Congo red,Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,YVS,32326350,PubMed,10.3390/ijms21082912,Int J Mol Sci.2020 Apr 21;21(8):2912,lxu@bio.ecnu.edu.cn,"The S1407P mutation exhibited decreased spore germination rate and infection cushion formation, and increased sensitivity to cell wall stress.",X Chen 2020,2020,1 gene,Chen-2020-A Single Nucleotide Mutation in Aden,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16159,PHI:10311,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,S1407P,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),subsp. sylvestris (wild grape),,,fruit,adenylate cyclase,,,,reduced virulence,,,,,,aberrant,,reduced,reduced,no,Congo red,Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,YVS,32326350,PubMed,10.3390/ijms21082912,Int J Mol Sci.2020 Apr 21;21(8):2912,lxu@bio.ecnu.edu.cn,"The S1407P mutation exhibited decreased spore germination rate and infection cushion formation, and increased sensitivity to cell wall stress.",X Chen 2020,2020,1 gene,Chen-2020-A Single Nucleotide Mutation in Aden,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16160,PHI:10311,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,S1407P,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: paradise apple),,,,fruit,adenylate cyclase,,,,reduced virulence,,,,,,aberrant,,reduced,reduced,no,Congo red,Congo red: CHEBI:34653,,,,,gene mutation; gene complementation,,,YVS,32326350,PubMed,10.3390/ijms21082912,Int J Mol Sci.2020 Apr 21;21(8):2912,lxu@bio.ecnu.edu.cn,"The S1407P mutation exhibited decreased spore germination rate and infection cushion formation, and increased sensitivity to cell wall stress.",X Chen 2020,2020,1 gene,Chen-2020-A Single Nucleotide Mutation in Aden,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16161,PHI:10312,UniProt,P31554,GenBank,BAA34130,,,K-12,LptD,,G580S,,,,,562,Escherichia coli,,KP7600,urinary tract infection,moths,7091,Bombyx mori (related: domestic silkworm),,,,,LPS-assembly protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,cholic acid; vancomycin; n-hexane; chloramphenicol,cholic acid: CHEBI:16359; vancomycin: CHEBI:28001; n-hexane: CHEBI:29021; chloramphenicol: CHEBI:17698,,,,,gene mutation,,,YVS,32324807,PubMed,10.1371/journal.ppat.1008469,PLoS Pathog.2020 Apr 23;16(4):e1008469,ckaito@okayama-u.ac.jp,LptD G580S and LptE T95I exhibited increased production of outer membrane vesicles.,C Kaito 2020,2020,2 genes,Kaito-2020-Non-pathogenic Escherichia coli acq,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16162,PHI:10313,UniProt,P0ADC1,GenBank,BAA35288,,,K-12,LptE,,T95I,,,,,562,Escherichia coli,,KP7600,urinary tract infection,moths,7091,Bombyx mori (related: domestic silkworm),,,,,LPS-assembly protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,cholic acid; vancomycin; n-hexane; chloramphenicol,cholic acid: CHEBI:16359; vancomycin: CHEBI:28001; n-hexane: CHEBI:29021; chloramphenicol: CHEBI:17698,,,,,gene mutation,,,YVS,32324807,PubMed,10.1371/journal.ppat.1008469,PLoS Pathog.2020 Apr 23;16(4):e1008469,ckaito@okayama-u.ac.jp,LptD G580S and LptE T95I exhibited increased production of outer membrane vesicles.,C Kaito 2020,2020,2 genes,Kaito-2020-Non-pathogenic Escherichia coli acq,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16163,PHI:10312,UniProt,P31554,GenBank,BAA34130,,,K-12,LptD,,G580S,,,,,562,Escherichia coli,,KP7600,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,feces,LPS-assembly protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,cholic acid; vancomycin; n-hexane; chloramphenicol,cholic acid: CHEBI:16359; vancomycin: CHEBI:28001; n-hexane: CHEBI:29021; chloramphenicol: CHEBI:17698,,,,,gene mutation,,,YVS,32324807,PubMed,10.1371/journal.ppat.1008469,PLoS Pathog.2020 Apr 23;16(4):e1008469,ckaito@okayama-u.ac.jp,LptD G580S and LptE T95I exhibited increased production of outer membrane vesicles.,C Kaito 2020,2020,2 genes,Kaito-2020-Non-pathogenic Escherichia coli acq,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16164,PHI:10313,UniProt,P0ADC1,GenBank,BAA35288,,,K-12,LptE,,T95I,,,,,562,Escherichia coli,,KP7600,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,feces,LPS-assembly protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,cholic acid; vancomycin; n-hexane; chloramphenicol,cholic acid: CHEBI:16359; vancomycin: CHEBI:28001; n-hexane: CHEBI:29021; chloramphenicol: CHEBI:17698,,,,,gene mutation,,,YVS,32324807,PubMed,10.1371/journal.ppat.1008469,PLoS Pathog.2020 Apr 23;16(4):e1008469,ckaito@okayama-u.ac.jp,LptD G580S and LptE T95I exhibited increased production of outer membrane vesicles.,C Kaito 2020,2020,2 genes,Kaito-2020-Non-pathogenic Escherichia coli acq,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16165,PHI:10314,UniProt,J4WG70,GenBank,EJP68925,,,ARSEF 2860,ssr4 (BBA_01960),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,SWI/SNF and RSC complexes subunit,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32317391,PubMed,10.1128/mSystems.00677-19,mSystems.2020 Apr 21;5(2):e00677-19,mgfeng@zju.edu.cn,"Deletion of ssr4 resulted in severe growth defects on different carbon/nitrogen sources, increased hyphal hydrophilicity, blocked hyphal differentiation and 98% reduced conidiation capacity.",W Shao 2020,2020,1 gene,Shao-2020-Nuclear Ssr4 Is Required for the In,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16166,PHI:10315,,no data found,,,,,,SCP27,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16167,PHI:10316,,no data found,,,,,,SCP113,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16168,PHI:10317,,no data found,,,,,,SCP126,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16169,PHI:10315,,no data found,,,,,,SCP27,,,,,,PHI:10316,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16170,PHI:10316,,no data found,,,,,,SCP113,,,,,,PHI:10315,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16171,PHI:10315,,no data found,,,,,,SCP27,,,,,,PHI:10317,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16172,PHI:10317,,no data found,,,,,,SCP126,,,,,,PHI:10315,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16173,PHI:10316,,no data found,,,,,,SCP113,,,,,,PHI:10317,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16174,PHI:10317,,no data found,,,,,,SCP126,,,,,,PHI:10316,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16175,PHI:10315,,no data found,,,,,,SCP27,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16176,PHI:10316,,no data found,,,,,,SCP113,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16177,PHI:10317,,no data found,,,,,,SCP126,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16178,PHI:10315,,no data found,,,,,,SCP27,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16179,PHI:10316,,no data found,,,,,,SCP113,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16180,PHI:10317,,no data found,,,,,,SCP126,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16181,PHI:10315,,no data found,,,,,,SCP27,,,,,,PHI:10316,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16182,PHI:10316,,no data found,,,,,,SCP113,,,,,,PHI:10315,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16183,PHI:10315,,no data found,,,,,,SCP27,,,,,,PHI:10317,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted small cysteine-rich protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16184,PHI:10317,,no data found,,,,,,SCP126,,,,,,PHI:10315,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted small cysteine-rich protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16185,PHI:10316,,no data found,,,,,,SCP113,,,,,,PHI:10317,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16186,PHI:10317,,no data found,,,,,,SCP126,,,,,,PHI:10316,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted small cysteine-rich protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32314529,PubMed,10.1111/mpp.12921,Mol Plant Pathol.2020 May;21(5):667-685,daixiaofeng0002@126.com,"The expression of these three proteins, VdSCP27, VdSCP113, and VdSCP126, in N. benthamiana resulted in cell death accompanied by a reactive oxygen species burst, callose deposition, and induction of defence genes.",D Wang 2020,2020,3 genes,Wang-2020-Functional analyses of small secrete,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16187,PHI:10318,UniProt,P43079,GenBank,AOW26385,,,SC5314,cph1,chromosome 1,,,,,PHI:10319,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,TR-146 cell,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32345638,PubMed,10.1128/mBio.00206-20,mBio.2020 Apr 28;11(2):e00206-20,ronny.martin@uni-wuerzburg.de,Ahr1 and Tup1 are key contributors in the complex regulation of virulence-associated genes in the different C. albicans,S Ruben 2020,2020,3 genes,Ruben-2020-Ahr1 and Tup1 Contribute to the Tra,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16188,PHI:10319,UniProt,Q59X67,GenBank,AOW31479,,,SC5314,efg1,chromosome R,,,,,PHI:10318,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,TR-146 cell,enhanced filamentous growth protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32345638,PubMed,10.1128/mBio.00206-20,mBio.2020 Apr 28;11(2):e00206-20,ronny.martin@uni-wuerzburg.de,Ahr1 and Tup1 are key contributors in the complex regulation of virulence-associated genes in the different C. albicans,S Ruben 2020,2020,3 genes,Ruben-2020-Ahr1 and Tup1 Contribute to the Tra,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16189,PHI:10318,UniProt,P43079,GenBank,AOW26385,,,SC5314,cph1,chromosome 1,,,,,PHI:10319; PHI:10320,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,TR-146 cell,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32345638,PubMed,10.1128/mBio.00206-20,mBio.2020 Apr 28;11(2):e00206-20,ronny.martin@uni-wuerzburg.de,Ahr1 and Tup1 are key contributors in the complex regulation of virulence-associated genes in the different C. albicans,S Ruben 2020,2020,3 genes,Ruben-2020-Ahr1 and Tup1 Contribute to the Tra,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16190,PHI:10319,UniProt,Q59X67,GenBank,AOW31479,,,SC5314,efg1,chromosome R,,,,,PHI:10318; PHI:10320,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,TR-146 cell,enhanced filamentous growth protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32345638,PubMed,10.1128/mBio.00206-20,mBio.2020 Apr 28;11(2):e00206-20,ronny.martin@uni-wuerzburg.de,Ahr1 and Tup1 are key contributors in the complex regulation of virulence-associated genes in the different C. albicans,S Ruben 2020,2020,3 genes,Ruben-2020-Ahr1 and Tup1 Contribute to the Tra,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16191,PHI:10320,UniProt,Q5A4F3,GenBank,AOW28608,,,SC5314,Ahr1,chromosome 3,,,,,PHI:10318; PHI:10319,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,TR-146 cell,adhesion and hyphal regulator 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32345638,PubMed,10.1128/mBio.00206-20,mBio.2020 Apr 28;11(2):e00206-20,ronny.martin@uni-wuerzburg.de,Ahr1 and Tup1 are key contributors in the complex regulation of virulence-associated genes in the different C. albicans,S Ruben 2020,2020,3 genes,Ruben-2020-Ahr1 and Tup1 Contribute to the Tra,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16192,PHI:10321,UniProt,B8N2M2,GenBank,EED56523,,,NRRL3357,Aflset1,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,methyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red; calcofluor white; methylmercuric sulphate,hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; methylmercuric sulphate: CAS:3810-81-9,,,,,gene deletion: full; gene complementation,,,YVS,32132990,PubMed,10.3389/fmicb.2020.00234,Front Microbiol. 2020 Feb 18;11:234,wshyyl@sina.com,"AflSet1 was deeply involved in fungal resistance against osmotic, oxidative and cell membrane stress.",Y Liu 2020,2020,1 gene,Liu-2020-The Methyltransferase AflSet1 Is Invo,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16193,PHI:10321,UniProt,B8N2M2,GenBank,EED56523,,,NRRL3357,Aflset1,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,cotyledon,methyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,hydrogen peroxide (H2O2); NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red; calcofluor white; methylmercuric sulphate,hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; methylmercuric sulphate: CAS:3810-81-9,,,,,gene deletion: full; gene complementation,,,YVS,32132990,PubMed,10.3389/fmicb.2020.00234,Front Microbiol. 2020 Feb 18;11:234,wshyyl@sina.com,"AflSet1 was deeply involved in fungal resistance against osmotic, oxidative and cell membrane stress.",Y Liu 2020,2020,1 gene,Liu-2020-The Methyltransferase AflSet1 Is Invo,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16194,PHI:10322,UniProt,J9VRC4,GenBank,AFR94270,,,H99,atg1 (CNAG_05005),chromosome 4,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,ULK/ULK protein kinase,,,,reduced virulence,yes,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16195,PHI:10323,UniProt,J9VFE3,GenBank,AFR93067,,,H99,atg2 (CNAG_06732),chromosome 2,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,uncharacterized protein,,,,unaffected pathogenicity,yes,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16196,PHI:10324,UniProt,J9VIW1,GenBank,AFR94148,,,H99,atg3 (CNAG_06892),chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,autophagy-related protein 3,,,,unaffected pathogenicity,yes,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16197,PHI:10325,UniProt,J9VN57,GenBank,AFR94029,,,H99,atg4 (CNAG_02662),chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,cysteine protease,,,,reduced virulence,yes,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16198,PHI:10326,UniProt,J9VWV8,GenBank,AFR98748,,,H99,atg5 (CNAG_06519),chromosome 13,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,autophagy protein 5,,,,unaffected pathogenicity,yes,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16199,PHI:10327,UniProt,J9VX66,GenBank,AFR97976,,,H99,atg6 (CNAG_01773),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,beclin 1,,,,loss of pathogenicity,yes,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16200,PHI:10328,UniProt,J9VS05,GenBank,AFR97257,,,H99,atg7 (CNAG_04538),chromosome 9,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,ubiquitin-like modifier-activating enzyme ATG7,,,,reduced virulence,yes,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16201,PHI:10329,UniProt,J9VF50,GenBank,AFR92947,,,H99,atg8 (CNAG_00816),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,microtubule binding protein,,,,reduced virulence,yes,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16202,PHI:10330,UniProt,J9VKC3,GenBank,AFR94698,,,H99,atg9 (CNAG_01445),chromosome 5,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,autophagy-like protein 9,,,,reduced virulence,yes,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16203,PHI:10331,UniProt,J9VV55,GenBank,AFR95590,,,H99,atg12 (CNAG_07645),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,ubiquitin-like protein,,,,reduced virulence,yes,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16204,PHI:10332,UniProt,J9VK04,GenBank,AFR92909,,,H99,atg13 (CNAG_00778),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,autophagy-related protein 13,,,,reduced virulence,yes,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16205,PHI:10333,UniProt,J9VFI3,GenBank,AFR93112,,,H99,atg14 (CNAG_03608),chromosome 2,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,uncharacterized protein,,,,loss of pathogenicity,yes,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16206,PHI:10334,UniProt,J9VL02,GenBank,AFR94116,,,H99,atg16 (CNAG_02576),chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,ATG16 domain-containing protein,,,,reduced virulence,yes,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16207,PHI:10335,UniProt,J9VM57,GenBank,AFR95557,,,H99,atg18 (CNAG_02269),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,autophagy-like protein 18,,,,loss of pathogenicity,yes,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32528953,PubMed,10.3389/fcell.2020.00374,Front Cell Dev Biol. 2020; 8: 374,tongbaoliu@swu.edu.cn,Fungal mating assays showed that all the 14 ATGs were essential for fungal sexual reproduction as basidiospore production was blocked in bilateral mating between each atg1 mutants.,S T Jiang 2020,2020,14 genes,Jiang-2020-Autophagy Regulates Fungal Virulenc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16208,PHI:10336,UniProt,Q5AFK0,GenBank,AOW30430,,,SC5314,mac1,chromosome 7,,,,,,5476,Candida albicans,,SN250,oral candidiasis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,enterocyte,copper utilization regulator,,,,reduced virulence,,,,,,,,,,no,ketoconazole; amphotericin B; fluconazole; miconazole,ketoconazole: CHEBI:48336; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; miconazole: CHEBI:6923,,,,,gene mutation; gene complementation,,,YVS,32508775,PubMed,10.3389/fmicb.2020.00935,Front Microbiol. 2020 May 19;11:935,adnane.sellam@gmail.com,Mac1 was required for the invasion and adhesion to host cells and antifungal tolerance.,I Khemiri 2020,2020,1 gene,Khemiri-2020-Transcriptome Analysis Uncovers a,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16209,PHI:10337,UniProt,Q4WHC8,GenBank,EAL87677,,,Af293,pmrA (Afu2g05860),chromosome 2,,,,,,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,"calcium/mangenease P-type ATPase, putative",,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16210,PHI:10338,UniProt,Q4WND5,GenBank,EAL88529,,,Af293,srcA (Afu6g06740),chromosome 6,,,,,,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,calcium-transporting ATPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16211,PHI:10337,UniProt,Q4WHC8,GenBank,EAL87677,,,Af293,pmrA (Afu2g05860),chromosome 2,,,,,PHI:10338,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,"calcium/mangenease P-type ATPase, putative",,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16212,PHI:10338,UniProt,Q4WND5,GenBank,EAL88529,,,Af293,srcA (Afu6g06740),chromosome 6,,,,,PHI:10337,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,calcium-transporting ATPase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16213,PHI:10337,UniProt,Q4WHC8,GenBank,EAL87677,,,Af293,pmrA (Afu2g05860),chromosome 2,,,,,,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"calcium/mangenease P-type ATPase, putative",,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16214,PHI:10338,UniProt,Q4WND5,GenBank,EAL88529,,,Af293,srcA (Afu6g06740),chromosome 6,,,,,,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,calcium-transporting ATPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16215,PHI:10337,UniProt,Q4WHC8,GenBank,EAL87677,,,Af293,pmrA (Afu2g05860),chromosome 2,,,,,PHI:10338,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"calcium/mangenease P-type ATPase, putative",,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16216,PHI:10338,UniProt,Q4WND5,GenBank,EAL88529,,,Af293,srcA (Afu6g06740),chromosome 6,,,,,PHI:10337,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,calcium-transporting ATPase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16217,PHI:10337,UniProt,Q4WHC8,GenBank,EAL87677,,,Af293,pmrA (Afu2g05860),chromosome 2,,,,,,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"calcium/mangenease P-type ATPase, putative",,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16218,PHI:10338,UniProt,Q4WND5,GenBank,EAL88529,,,Af293,srcA (Afu6g06740),chromosome 6,,,,,,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,calcium-transporting ATPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16219,PHI:10337,UniProt,Q4WHC8,GenBank,EAL87677,,,Af293,pmrA (Afu2g05860),chromosome 2,,,,,PHI:10338,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"calcium/mangenease P-type ATPase, putative",,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16220,PHI:10338,UniProt,Q4WND5,GenBank,EAL88529,,,Af293,srcA (Afu6g06740),chromosome 6,,,,,PHI:10337,746128,Aspergillus fumigatus,,ku70,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,calcium-transporting ATPase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32487759,PubMed,10.1128/mBio.01060-20,mBio. 2020 Jun 2;11(3):e01060-20,david.askew@uc.edu,"ΔsrcA/ΔpmrA mutant displayed a severe polarity defect, was hypersensitive to ER stress, and showed attenuated virulence.",M Weichert 2020,2020,2 genes,Weichert-2020-Functional Coupling between the,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16221,PHI:10339,,no data found,,,,,,decr,,,,,,,5664,Leishmania major,,WHOM/IR/-/173,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"putative 2,4-dienoyl-coenzyme A (CoA) reductase",,,,loss of pathogenicity,,,,,,,,,,no,dithiothreitol; N-acetyl-L-cysteine,dithiothreitol (DTT): CHEBI:42170; N-acetyl-L-cysteine: CHEBI:28939,,,,,gene deletion: full; gene complementation,,,YVS,32487758,PubMed,10.1128/mBio.01057-20,mBio. 2020 Jun 2;11(3):e01057-20,AebischerA@rki.de,L. major Δdecr mutant was unable to survive in macrophages and was avirulent in BALB/c mice.,G Semini 2020,2020,1 gene,Semini-2020-Leishmania Encodes a Bacterium-lik,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16222,PHI:10339,,no data found,,,,,,decr,,,,,,,5664,Leishmania major,,WHOM/IR/-/173,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,"putative 2,4-dienoyl-coenzyme A (CoA) reductase",,,,loss of pathogenicity,,,,,,,,,,no,dithiothreitol; N-acetyl-L-cysteine,dithiothreitol (DTT): CHEBI:42170; N-acetyl-L-cysteine: CHEBI:28939,,,,,gene deletion: full; gene complementation,,,YVS,32487758,PubMed,10.1128/mBio.01057-20,mBio. 2020 Jun 2;11(3):e01057-20,AebischerA@rki.de,L. major Δdecr mutant was unable to survive in macrophages and was avirulent in BALB/c mice.,G Semini 2020,2020,1 gene,Semini-2020-Leishmania Encodes a Bacterium-lik,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16223,PHI:10340,UniProt,P06179,GenBank,AAL20871,,,LT2,fliC,,,,,,PHI:10341,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,phase 1 flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32485895,PubMed,10.3390/microorganisms8060815,Microorganisms. 2020 May 29;8(6):E815,adam.schikora@julius-kuehn.de,"No differences were detected between these strains concerning their respective abilities to reach distal, non-inoculated parts of the plant.",A A Zarkani 2020,2020,2 genes,Zarkani-2020-Salmonella Heterogeneously Expres,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16224,PHI:10341,UniProt,P52616,GenBank,AAL21657,,,,fljB,,,,,,PHI:10340,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,phase 2 flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32485895,PubMed,10.3390/microorganisms8060815,Microorganisms. 2020 May 29;8(6):E815,adam.schikora@julius-kuehn.de,"No differences were detected between these strains concerning their respective abilities to reach distal, non-inoculated parts of the plant.",A A Zarkani 2020,2020,2 genes,Zarkani-2020-Salmonella Heterogeneously Expres,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16225,PHI:10342,UniProt,A0A550KY48,GenBank,TGB21132,,,Y3X,ntrB,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,heart; liver; lung; spleen; kidney,"nitrate ABC transporter, permease protein",,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32431676,PubMed,10.3389/fmicb.2020.00773,Front Microbiol. 2020 May 5;11:773,bob@hancocklab.com,"Mutants (ΔntrB, ΔntrC, and ΔntrBC) were reduced in their ability to invade and cause damage in a high-density abscess model in vivo.",M A Alford 2020,2020,2 genes,Alford-2020-NtrBC Regulates Invasiveness and V,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16226,PHI:10343,UniProt,A0A072ZJC4,GenBank,CEI13406,,,MH19,ntrC,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,heart; liver; lung; spleen; kidney,DNA-binding transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32431676,PubMed,10.3389/fmicb.2020.00773,Front Microbiol. 2020 May 5;11:773,bob@hancocklab.com,"Mutants (ΔntrB, ΔntrC, and ΔntrBC) were reduced in their ability to invade and cause damage in a high-density abscess model in vivo.",M A Alford 2020,2020,2 genes,Alford-2020-NtrBC Regulates Invasiveness and V,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16227,PHI:10342,UniProt,A0A550KY48,GenBank,TGB21132,,,Y3X,ntrB,,,,,,PHI:10343,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,heart; liver; lung; spleen; kidney,"nitrate ABC transporter, permease protein",,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32431676,PubMed,10.3389/fmicb.2020.00773,Front Microbiol. 2020 May 5;11:773,bob@hancocklab.com,"Mutants (ΔntrB, ΔntrC, and ΔntrBC) were reduced in their ability to invade and cause damage in a high-density abscess model in vivo.",M A Alford 2020,2020,2 genes,Alford-2020-NtrBC Regulates Invasiveness and V,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16228,PHI:10343,UniProt,A0A072ZJC4,GenBank,CEI13406,,,MH19,ntrC,,,,,,PHI:10342,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,heart; liver; lung; spleen; kidney,DNA-binding transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32431676,PubMed,10.3389/fmicb.2020.00773,Front Microbiol. 2020 May 5;11:773,bob@hancocklab.com,"Mutants (ΔntrB, ΔntrC, and ΔntrBC) were reduced in their ability to invade and cause damage in a high-density abscess model in vivo.",M A Alford 2020,2020,2 genes,Alford-2020-NtrBC Regulates Invasiveness and V,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16229,PHI:10344,,no data found,,,,,,fakA,,,,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,thigh,fatty acid kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32430471,PubMed,10.1128/mBio.00920-20,mBio. 2020 May-Jun; 11(3): e00920-20,charles.rock@stjude.org,Inactivation of host FA utilization did not impact the virulence of S. aureus in the thigh model.,M W Frank 2020,2020,5 genes,Frank-2020-Host Fatty Acid Utilization by Stap,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16230,PHI:10345,UniProt,A0A6B0BG40,GenBank,MVI57412,,,S_4031.LGMP.AI,fakB1,,,,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,thigh,fatty acid kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32430471,PubMed,10.1128/mBio.00920-20,mBio. 2020 May-Jun; 11(3): e00920-20,charles.rock@stjude.org,Inactivation of host FA utilization did not impact the virulence of S. aureus in the thigh model.,M W Frank 2020,2020,5 genes,Frank-2020-Host Fatty Acid Utilization by Stap,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16231,PHI:10346,UniProt,A0A4T9YUF5,GenBank,QBZ85624,,,WCUH29,fakB2,,,,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,thigh,fatty acid kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32430471,PubMed,10.1128/mBio.00920-20,mBio. 2020 May-Jun; 11(3): e00920-20,charles.rock@stjude.org,Inactivation of host FA utilization did not impact the virulence of S. aureus in the thigh model.,M W Frank 2020,2020,5 genes,Frank-2020-Host Fatty Acid Utilization by Stap,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16232,PHI:10346,UniProt,A0A4T9YUF5,GenBank,QBZ85624,,,WCUH29,fakB2,,,,,,PHI:10345,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,thigh,fatty acid kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32430471,PubMed,10.1128/mBio.00920-20,mBio. 2020 May-Jun; 11(3): e00920-20,charles.rock@stjude.org,Inactivation of host FA utilization did not impact the virulence of S. aureus in the thigh model.,M W Frank 2020,2020,5 genes,Frank-2020-Host Fatty Acid Utilization by Stap,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16233,PHI:10345,UniProt,A0A6B0BG40,GenBank,MVI57412,,,S_4031.LGMP.AI,fakB1,,,,,,PHI:10346,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,thigh,fatty acid kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32430471,PubMed,10.1128/mBio.00920-20,mBio. 2020 May-Jun; 11(3): e00920-20,charles.rock@stjude.org,Inactivation of host FA utilization did not impact the virulence of S. aureus in the thigh model.,M W Frank 2020,2020,5 genes,Frank-2020-Host Fatty Acid Utilization by Stap,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16234,PHI:10347,UniProt,X5ELF9,GenBank,AUS74912,,,MRSA107,plsX,,,,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,thigh,phosphate acyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32430471,PubMed,10.1128/mBio.00920-20,mBio. 2020 May-Jun; 11(3): e00920-20,charles.rock@stjude.org,Inactivation of host FA utilization did not impact the virulence of S. aureus in the thigh model.,M W Frank 2020,2020,5 genes,Frank-2020-Host Fatty Acid Utilization by Stap,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16235,PHI:10348,UniProt,Q5HF73,GenBank,AAW36851,,,COL,accD,,,,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,thigh,acetyl-coenzyme A carboxylase carboxyl transferase subunit beta,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32430471,PubMed,10.1128/mBio.00920-20,mBio. 2020 May-Jun; 11(3): e00920-20,charles.rock@stjude.org,Inactivation of host FA utilization did not impact the virulence of S. aureus in the thigh model.,M W Frank 2020,2020,5 genes,Frank-2020-Host Fatty Acid Utilization by Stap,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16236,PHI:10349,UniProt,Q9I5D3,GenBank,AE004515_10,,,PAO1,PA0805.1,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,primates,9606,Homo sapiens (related: human),HBE cell line,,,bronchial epithelial cell line,small noncoding RNA,,,,reduced virulence,,,,,,,,,,no,tobramycin,tobramycin: CHEBI:28864,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32430407,PubMed,10.1128/mSystems.00204-20,mSystems. 2020 May 19;5(3):e00204-20,bob@hancocklab.com,"Overexpression of PA0805.1 reduced swarming, swimming, and twitching motilities, as well as increased adherence, cytotoxicity, and tobramycin resistance.",S R Coleman 2020,2020,1 gene,Coleman-2020-Overexpression of the Small RNA P,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16237,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,158878,Mu50,septic shock,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; lung; kidney,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16238,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,158878,Mu50,septic shock,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16239,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,158878,Mu50,septic shock,primates,9606,Homo sapiens (related: human),MCF-7 cell line,,,MCF-7 cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16240,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,158878,Mu50,septic shock,primates,9606,Homo sapiens (related: human),HCMEC,,,HCMEC cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16241,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,158878,Mu50,septic shock,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16242,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,158878,Mu50,septic shock,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16243,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,,BA01611,septic shock,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16244,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,,BA01611,septic shock,primates,9606,Homo sapiens (related: human),MCF-7 cell line,,,MCF-7 cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16245,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,,BA01611,septic shock,primates,9606,Homo sapiens (related: human),HCMEC,,,HCMEC cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16246,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,,BA01611,septic shock,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16247,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,426430,Newman,septic shock,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16248,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,426430,Newman,septic shock,primates,9606,Homo sapiens (related: human),MCF-7 cell line,,,MCF-7 cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16249,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,426430,Newman,septic shock,primates,9606,Homo sapiens (related: human),HCMEC,,,HCMEC cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16250,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,426430,Newman,septic shock,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16251,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,561307,RN4220,septic shock,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16252,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,561307,RN4220,septic shock,primates,9606,Homo sapiens (related: human),MCF-7 cell line,,,MCF-7 cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16253,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,561307,RN4220,septic shock,primates,9606,Homo sapiens (related: human),HCMEC,,,HCMEC cell,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16254,PHI:10350,,no data found,,,,,,lcpC,,,,,,,1280,Staphylococcus aureus,561307,RN4220,septic shock,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,"cell wall ligase, LytR-CpsA-Psr protein",,,,reduced virulence,,,,,,,,,,no,oxacillin; teicoplanin; cefazolin; penicillin; vancomycin; ciprofloxacin; tetracycline; chloramphenicol; streptomycin,oxacillin: CHEBI:7809; teicoplanin: CHEBI:29687; cefazolin: CHEBI:474053; penicillin: CHEBI:17334; vancomycin: CHEBI:28001; ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32425893,PubMed,10.3389/fmicb.2020.00557,Front Microbiol. 2020 Apr 16;11:557,xin.zhao@mcgill.ca,Deficiency in LcpC decreased the antimicrobial resistance to beta-lactams and glycopeptides and impeded the binding to various epithelial cells.,F Li 2020,2020,1 gene,"Li-2020-Impairment of the Cell Wall Ligase, Ly",BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16255,PHI:10351,UniProt,Q2YPB1,GenBank,CAJ10216,,,2308,FlgJ (BAB1_0260),chromosome I,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,flagellar protein; peptidoglycan hydrolase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32411617,PubMed,10.3389/fcimb.2020.00178,Front Cell Infect Microbiol. 2020 Apr 28;10:178,aonate@udec.cl,"Elimination of the flgJ gene delayed the growth rate of B. abortus in culture, reduced its intracellular survival capacity in professional and non-professional phagocytic cells.",R F C Rivero 2020,2020,1 gene,Coloma-Rivero-2020-The Role of the Flagellar P,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16256,PHI:10351,UniProt,Q2YPB1,GenBank,CAJ10216,,,2308,FlgJ (BAB1_0260),chromosome I,,,,,,235,Brucella abortus,359391,2308,brucellosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,flagellar protein; peptidoglycan hydrolase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32411617,PubMed,10.3389/fcimb.2020.00178,Front Cell Infect Microbiol. 2020 Apr 28;10:178,aonate@udec.cl,"Elimination of the flgJ gene delayed the growth rate of B. abortus in culture, reduced its intracellular survival capacity in professional and non-professional phagocytic cells.",R F C Rivero 2020,2020,1 gene,Coloma-Rivero-2020-The Role of the Flagellar P,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16257,PHI:10351,UniProt,Q2YPB1,GenBank,CAJ10216,,,2308,FlgJ (BAB1_0260),chromosome I,,,,,,235,Brucella abortus,359391,2308,brucellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,flagellar protein; peptidoglycan hydrolase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32411617,PubMed,10.3389/fcimb.2020.00178,Front Cell Infect Microbiol. 2020 Apr 28;10:178,aonate@udec.cl,"Elimination of the flgJ gene delayed the growth rate of B. abortus in culture, reduced its intracellular survival capacity in professional and non-professional phagocytic cells.",R F C Rivero 2020,2020,1 gene,Coloma-Rivero-2020-The Role of the Flagellar P,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16258,PHI:10352,UniProt,J9VJ03,GenBank,AFR94407,,,H99,alg3 (CNAG_05142),chromosome 4,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,"dolichyl-phosphate-mannose (dol-P-man)-dependent-1,3-mannosyltransferase",,,,loss of pathogenicity,,,,,,,,wild type,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16259,PHI:10352,UniProt,J9VJ03,GenBank,AFR94407,,,H99,alg3 (CNAG_05142),chromosome 4,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"dolichyl-phosphate-mannose (dol-P-man)-dependent-1,3-mannosyltransferase",,,,unaffected pathogenicity,,,,,,,,wild type,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16260,PHI:10352,UniProt,J9VJ03,GenBank,AFR94407,,,H99,alg3 (CNAG_05142),chromosome 4,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,"dolichyl-phosphate-mannose (dol-P-man)-dependent-1,3-mannosyltransferase",,,,reduced virulence,,,,,,,,wild type,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16261,PHI:10352,UniProt,J9VJ03,GenBank,AFR94407,,,H99,alg3 (CNAG_05142),chromosome 4,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,"dolichyl-phosphate-mannose (dol-P-man)-dependent-1,3-mannosyltransferase",,,,reduced virulence,,,,,,,,wild type,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16262,PHI:10353,UniProt,E0XG07,GenBank,AAC13946,,,,cap59,,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,capsular-associated protein,,,,unaffected pathogenicity,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16263,PHI:10353,UniProt,E0XG07,GenBank,AAC13946,,,,cap59,,,,,,PHI:10352,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,capsular-associated protein,,,,reduced virulence,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16264,PHI:10352,UniProt,J9VJ03,GenBank,AFR94407,,,H99,alg3 (CNAG_05142),chromosome 4,,,,,PHI:10353,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,"dolichyl-phosphate-mannose (dol-P-man)-dependent-1,3-mannosyltransferase",,,,reduced virulence,,,,,,,,wild type,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16265,PHI:10353,UniProt,E0XG07,GenBank,AAC13946,,,,cap59,,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,capsular-associated protein,,,,unaffected pathogenicity,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16266,PHI:10353,UniProt,E0XG07,GenBank,AAC13946,,,,cap59,,,,,,PHI:10352,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,capsular-associated protein,,,,reduced virulence,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16267,PHI:10352,UniProt,J9VJ03,GenBank,AFR94407,,,H99,alg3 (CNAG_05142),chromosome 4,,,,,PHI:10353,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,"dolichyl-phosphate-mannose (dol-P-man)-dependent-1,3-mannosyltransferase",,,,reduced virulence,,,,,,,,wild type,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16268,PHI:10353,UniProt,E0XG07,GenBank,AAC13946,,,,cap59,,,,,,PHI:10354,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,capsular-associated protein,,,,reduced virulence,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16269,PHI:10354,UniProt,J9VWV3,GenBank,AFR96200,,,H99,alg9 (CNAG_05881),chromosome 7,,,,,PHI:10353,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,"alpha-1,2-mannosyltransferase",,,,reduced virulence,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16270,PHI:10353,UniProt,E0XG07,GenBank,AAC13946,,,,cap59,,,,,,PHI:10355,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,capsular-associated protein,,,,reduced virulence,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16271,PHI:10355,UniProt,J9VN17,GenBank,AFR93974,,,H99,alg12 (CNAG_02715),chromosome 3,,,,,PHI:10353,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,"alpha-1,6-mannosyltransferase",,,,reduced virulence,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16272,PHI:10353,UniProt,E0XG07,GenBank,AAC13946,,,,cap59,,,,,,PHI:10356,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,capsular-associated protein,,,,unaffected pathogenicity,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16273,PHI:10356,UniProt,Q55JF3,GenBank,XP_772554,,,B-3501A,och1,chromosome 12,,,,,PHI:10353,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage cell line,mannosyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16274,PHI:10354,UniProt,J9VWV3,GenBank,AFR96200,,,H99,alg9 (CNAG_05881),chromosome 7,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung,"alpha-1,2-mannosyltransferase",,,,reduced virulence,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16275,PHI:10355,UniProt,J9VN17,GenBank,AFR93974,,,H99,alg12 (CNAG_02715),chromosome 3,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung,"alpha-1,6-mannosyltransferase",,,,reduced virulence,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16276,PHI:10356,UniProt,Q55JF3,GenBank,XP_772554,,,B-3501A,och1,chromosome 12,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung,mannosyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16277,PHI:10352,UniProt,J9VJ03,GenBank,AFR94407,,,H99,alg3 (CNAG_05142),chromosome 4,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung,"dolichyl-phosphate-mannose (dol-P-man)-dependent-1,3-mannosyltransferase",,,,reduced virulence,,,,,,,,wild type,,no,dithiothreitol (DTT); calcofluor white (CFW); vanadate; fluconazole; tunicamycin (TM); Congo red (CR); sodium dodecyl sulfate (SDS); caffeine; NaCl; sorbitol; ketoconazole; fludioxonil,dithiothreitol (DTT): CHEBI:42170; calcofluor white (CFW): CHEBI:50011; vanadate: CHEBI:46442; fluconazole: CHEBI:46081; tunicamycin (TM): CHEBI:29699; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; caffeine: CHEBI:27732; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; ketoconazole: CHEBI:48336; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,32398313,PubMed,10.1128/mBio.00711-20,mBio. 2020 May-Jun; 11(3): e00711-20,hyunkang@cau.ac.kr,"The alg null mutants producing truncated core N-glycans were defective in inducing host cell death after phagocytosis, which was triggered as a mechanism of pulmonary escape and dissemination of C. neoformans, thus becoming inactive in causing fatal infection.",E J Thak 2020,2020,5 genes,Thak-2020-Core N-Glycan Structures Are Critica,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16278,PHI:10357,UniProt,A0A1B5KZM5,GenBank,GAO16575,,,IPU010,UvHrip1 (UVI_02019870),chromosome 4,,,,,,1159556,Ustilaginoidea virens,,P1,infection,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32397668,PubMed,10.3390/ijms21093376www,Int J Mol Sci. 2020 May; 21(9): 3376,lishuai@syau.edu.cn,UvHrip1 inhibited INF1-induced cell death in N.benthamiana.,S Wei 2020,2020,1 gene,Wei-2020-The Conserved Effector UvHrip1 intera,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16279,PHI:10358,UniProt,G4N560,GenBank,EHA52118,,,70-15,MoAa91 (MGG_06069),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,homolog of the auxiliary activity family 9 protein,,,,reduced virulence,,yes,yes,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32209696,PubMed,10.1128/mBio.03304-19,mBio. 2020 Mar-Apr; 11(2): e03304-19,zhgzhang@njau.edu.cn,MoAA91 disruption resulted in defects in both appressorium formation on the artificial inductive surface and full virulence of the pathogen.,Y Li 2020,2020,1 gene,Li-2020-Magnaporthe oryzae Auxiliary Activity,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16280,PHI:10359,,no data found,GenBank,ATV03511,,,O11,saeP,,,,,,,1280,Staphylococcus aureus,367830,USA300,infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,cognate sensor kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16281,PHI:10360,,no data found,GenBank,ATV03510,,,O11,saeQ,,,,,,,1280,Staphylococcus aureus,367830,USA300,infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,transmembrane protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16282,PHI:10359,,no data found,GenBank,ATV03511,,,O11,saeP,,,,,,PHI:10360,1280,Staphylococcus aureus,367830,USA300,infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,cognate sensor kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16283,PHI:10360,,no data found,GenBank,ATV03510,,,O11,saeQ,,,,,,PHI:10359,1280,Staphylococcus aureus,367830,USA300,infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,transmembrane protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16284,PHI:10359,,no data found,GenBank,ATV03511,,,O11,saeP,,,,,,PHI:10360; PHI:10361; PHI:10362,1280,Staphylococcus aureus,367830,USA300,infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,cognate sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16285,PHI:10360,,no data found,GenBank,ATV03510,,,O11,saeQ,,,,,,PHI:10359; PHI:10361; PHI:10362,1280,Staphylococcus aureus,367830,USA300,infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,transmembrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16286,PHI:10361,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,PHI:10359; PHI:10360; PHI:10362,1280,Staphylococcus aureus,367830,USA300,infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16287,PHI:10362,UniProt,Q2G2U1,GenBank,CAD89115,,,ISP479C,saeS,,,,,,PHI:10359; PHI:10360; PHI:10361,1280,Staphylococcus aureus,367830,USA300,infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,sensory kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16288,PHI:10359,,no data found,GenBank,ATV03511,,,O11,saeP,,,,,,,1280,Staphylococcus aureus,367830,USA300,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; soft-tissue,cognate sensor kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16289,PHI:10360,,no data found,GenBank,ATV03510,,,O11,saeQ,,,,,,,1280,Staphylococcus aureus,367830,USA300,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; soft-tissue,transmembrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16290,PHI:10359,,no data found,GenBank,ATV03511,,,O11,saeP,,,,,,PHI:10360,1280,Staphylococcus aureus,367830,USA300,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; soft-tissue; kidney,cognate sensor kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16291,PHI:10360,,no data found,GenBank,ATV03510,,,O11,saeQ,,,,,,PHI:10359,1280,Staphylococcus aureus,367830,USA300,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; soft-tissue; kidney,transmembrane protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16292,PHI:10359,,no data found,GenBank,ATV03511,,,O11,saeP,,,,,,PHI:10360; PHI:10361; PHI:10362,1280,Staphylococcus aureus,367830,USA300,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; soft-tissue,cognate sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16293,PHI:10360,,no data found,GenBank,ATV03510,,,O11,saeQ,,,,,,PHI:10359; PHI:10361; PHI:10362,1280,Staphylococcus aureus,367830,USA300,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; soft-tissue,transmembrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16294,PHI:10361,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,PHI:10359; PHI:10360; PHI:10362,1280,Staphylococcus aureus,367830,USA300,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; soft-tissue,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16295,PHI:10362,UniProt,Q2G2U1,GenBank,CAD89115,,,ISP479C,saeS,,,,,,PHI:10359; PHI:10360; PHI:10361,1280,Staphylococcus aureus,367830,USA300,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; soft-tissue,sensory kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32390958,PubMed,10.3389/fmicb.2020.00561,Front. Microbiol. 11:561,jovanka@montana.edu,The enhanced cytotoxicity of USA300 ΔsaeP cells toward human neutrophils correlated with an increased expression of bi-component leukocidins known to target these immune cells.,M M Collins 2020,2020,4 genes,Collins-2020-The Accessory Gene saeP of the Sa,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16296,PHI:10363,UniProt,A0A384K6V9,GenBank,ATZ58384,,,B05.10,BcCGF1 (BCIN_16g01820),chromosome BCIN16,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,conidial germination protein,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,,reduced,no,NaCl; KCl; H2O2; sodium dodecyl sulphate (SDS); Congo red (CR); dithiothreitol (DTT),NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,32301267,PubMed,10.1111/mpp.12934,Mol Plant Pathol. 2020 Jun;21(6):834-853,qmqin@jlu.edu.cn,Loss of BcCGF1 impaired endogenous ROS production and cAMP rescued the infection-related development in the BcCGF1 deletion strains.,M Z Zhang 2020,2020,8 genes,Zhang-2020-Transcriptome analysis and function,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16297,PHI:10363,UniProt,A0A384K6V9,GenBank,ATZ58384,,,B05.10,BcCGF1 (BCIN_16g01820),chromosome BCIN16,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,conidial germination protein,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,,reduced,no,NaCl; KCl; H2O2; sodium dodecyl sulphate (SDS); Congo red (CR); dithiothreitol (DTT),NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,32301267,PubMed,10.1111/mpp.12934,Mol Plant Pathol. 2020 Jun;21(6):834-853,qmqin@jlu.edu.cn,Loss of BcCGF1 impaired endogenous ROS production and cAMP rescued the infection-related development in the BcCGF1 deletion strains.,M Z Zhang 2020,2020,8 genes,Zhang-2020-Transcriptome analysis and function,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16298,PHI:10363,UniProt,A0A384K6V9,GenBank,ATZ58384,,,B05.10,BcCGF1 (BCIN_16g01820),chromosome BCIN16,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,conidial germination protein,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,,reduced,no,NaCl; KCl; H2O2; sodium dodecyl sulphate (SDS); Congo red (CR); dithiothreitol (DTT),NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,32301267,PubMed,10.1111/mpp.12934,Mol Plant Pathol. 2020 Jun;21(6):834-853,qmqin@jlu.edu.cn,Loss of BcCGF1 impaired endogenous ROS production and cAMP rescued the infection-related development in the BcCGF1 deletion strains.,M Z Zhang 2020,2020,8 genes,Zhang-2020-Transcriptome analysis and function,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16299,PHI:10364,UniProt,A0A384JBE1,GenBank,ATZ47873,,,B05.10,BCIN_03g01540,chromosome BCIN03,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,putative beta-glucosidase,,,,reduced virulence,,,,,,,,,,no,NaCl; KCl; H2O2; sodium dodecyl sulphate (SDS); Congo red (CR); dithiothreitol (DTT),NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,32301267,PubMed,10.1111/mpp.12934,Mol Plant Pathol. 2020 Jun;21(6):834-853,qmqin@jlu.edu.cn,Loss of BcCGF1 impaired endogenous ROS production and cAMP rescued the infection-related development in the BcCGF1 deletion strains.,M Z Zhang 2020,2020,8 genes,Zhang-2020-Transcriptome analysis and function,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16300,PHI:10365,UniProt,A0A384JSB2,GenBank,ATZ53410,,,B05.10,BcBGL1 (BCIN_09g02640),chromosome BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,putative beta-glucosidase,,,,reduced virulence,,,,,,,,,,no,NaCl; KCl; H2O2; sodium dodecyl sulphate (SDS); Congo red (CR); dithiothreitol (DTT),NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,32301267,PubMed,10.1111/mpp.12934,Mol Plant Pathol. 2020 Jun;21(6):834-853,qmqin@jlu.edu.cn,Loss of BcCGF1 impaired endogenous ROS production and cAMP rescued the infection-related development in the BcCGF1 deletion strains.,M Z Zhang 2020,2020,8 genes,Zhang-2020-Transcriptome analysis and function,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16301,PHI:10366,UniProt,A0A384JTB8,GenBank,ATZ53770,,,B05.10,BcBGL2 (BCIN_09g05460),chromosome BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,putative beta-glucosidase,,,,reduced virulence,,,,,,,,,,no,NaCl; KCl; H2O2; sodium dodecyl sulphate (SDS); Congo red (CR); dithiothreitol (DTT),NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,32301267,PubMed,10.1111/mpp.12934,Mol Plant Pathol. 2020 Jun;21(6):834-853,qmqin@jlu.edu.cn,Loss of BcCGF1 impaired endogenous ROS production and cAMP rescued the infection-related development in the BcCGF1 deletion strains.,M Z Zhang 2020,2020,8 genes,Zhang-2020-Transcriptome analysis and function,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16302,PHI:10367,UniProt,A0A384JWC5,GenBank,ATZ54567,,,B05.10,BcBGL3 (BCIN_10g05590),chromosome BCIN10,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,putative beta-glucosidase,,,,reduced virulence,,,,,,,,,,no,NaCl; KCl; H2O2; sodium dodecyl sulphate (SDS); Congo red (CR); dithiothreitol (DTT),NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,32301267,PubMed,10.1111/mpp.12934,Mol Plant Pathol. 2020 Jun;21(6):834-853,qmqin@jlu.edu.cn,Loss of BcCGF1 impaired endogenous ROS production and cAMP rescued the infection-related development in the BcCGF1 deletion strains.,M Z Zhang 2020,2020,8 genes,Zhang-2020-Transcriptome analysis and function,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16303,PHI:10368,UniProt,A0A384JDM0,GenBank,ATZ48686,,,B05.10,BcBGL4 (BCIN_03g08710),chromosome BCIN03,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,putative beta-glucosidase,,,,reduced virulence,,,,,,,,,,no,NaCl; KCl; H2O2; sodium dodecyl sulphate (SDS); Congo red (CR); dithiothreitol (DTT),NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,32301267,PubMed,10.1111/mpp.12934,Mol Plant Pathol. 2020 Jun;21(6):834-853,qmqin@jlu.edu.cn,Loss of BcCGF1 impaired endogenous ROS production and cAMP rescued the infection-related development in the BcCGF1 deletion strains.,M Z Zhang 2020,2020,8 genes,Zhang-2020-Transcriptome analysis and function,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16304,PHI:10369,UniProt,A0A384K1X9,GenBank,ATZ56846,,,B05.10,BcBGL5 (BCIN_14g00650),chromosome BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,putative beta-glucosidase,,,,reduced virulence,,,,,,,,,,no,NaCl; KCl; H2O2; sodium dodecyl sulphate (SDS); Congo red (CR); dithiothreitol (DTT),NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,32301267,PubMed,10.1111/mpp.12934,Mol Plant Pathol. 2020 Jun;21(6):834-853,qmqin@jlu.edu.cn,Loss of BcCGF1 impaired endogenous ROS production and cAMP rescued the infection-related development in the BcCGF1 deletion strains.,M Z Zhang 2020,2020,8 genes,Zhang-2020-Transcriptome analysis and function,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16305,PHI:10370,UniProt,A0A384JUP3,GenBank,ATZ54250,,,B05.10,BcBGL6 (BCIN_10g02650),chromosome BCIN10,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,putative beta-glucosidase,,,,reduced virulence,,,,,,,,,,no,NaCl; KCl; H2O2; sodium dodecyl sulphate (SDS); Congo red (CR); dithiothreitol (DTT),NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,32301267,PubMed,10.1111/mpp.12934,Mol Plant Pathol. 2020 Jun;21(6):834-853,qmqin@jlu.edu.cn,Loss of BcCGF1 impaired endogenous ROS production and cAMP rescued the infection-related development in the BcCGF1 deletion strains.,M Z Zhang 2020,2020,8 genes,Zhang-2020-Transcriptome analysis and function,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16306,PHI:10371,UniProt,A0A6B0BLK0,GenBank,MVI56578,,,S_4031.LGMP.AI,Rsp,,,,,,,1280,Staphylococcus aureus,93061,NCTC 8325,nosocomial infection; abscess; skin lesion,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,AraC family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32248753,PubMed,10.1080/22221751.2020.1752116,Emerg Microbes Infect. 2020 Dec;9(1):796-812,sunb@ustc.edu.cn,Rsp has no influence on the virulence of S.aureus ?agr strain in a subcutaneous abscess model of mice.,B Liu 2020,2020,2 genes,Liu-2020-Rsp promotes the transcription of vir,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16307,PHI:10372,UniProt,P0A0I7,GenBank,AAA26597,,,,Agr,,,,,,,1280,Staphylococcus aureus,93061,NCTC 8325,nosocomial infection; abscess; skin lesion,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,accessory gene regulator protein A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32248753,PubMed,10.1080/22221751.2020.1752116,Emerg Microbes Infect. 2020 Dec;9(1):796-812,sunb@ustc.edu.cn,Rsp has no influence on the virulence of S.aureus ?agr strain in a subcutaneous abscess model of mice.,B Liu 2020,2020,2 genes,Liu-2020-Rsp promotes the transcription of vir,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16308,PHI:10371,UniProt,A0A6B0BLK0,GenBank,MVI56578,,,S_4031.LGMP.AI,Rsp,,,,,,PHI:10372,1280,Staphylococcus aureus,93061,NCTC 8325,nosocomial infection; abscess; skin lesion,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,AraC family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32248753,PubMed,10.1080/22221751.2020.1752116,Emerg Microbes Infect. 2020 Dec;9(1):796-812,sunb@ustc.edu.cn,Rsp has no influence on the virulence of S.aureus ?agr strain in a subcutaneous abscess model of mice.,B Liu 2020,2020,2 genes,Liu-2020-Rsp promotes the transcription of vir,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16309,PHI:10372,UniProt,P0A0I7,GenBank,AAA26597,,,,Agr,,,,,,PHI:10371,1280,Staphylococcus aureus,93061,NCTC 8325,nosocomial infection; abscess; skin lesion,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,accessory gene regulator protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32248753,PubMed,10.1080/22221751.2020.1752116,Emerg Microbes Infect. 2020 Dec;9(1):796-812,sunb@ustc.edu.cn,Rsp has no influence on the virulence of S.aureus ?agr strain in a subcutaneous abscess model of mice.,B Liu 2020,2020,2 genes,Liu-2020-Rsp promotes the transcription of vir,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16310,PHI:10371,UniProt,A0A6B0BLK0,GenBank,MVI56578,,,S_4031.LGMP.AI,Rsp,,,,,,,1280,Staphylococcus aureus,93061,NCTC 8325,nosocomial infection; abscess; skin lesion,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,AraC family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32248753,PubMed,10.1080/22221751.2020.1752116,Emerg Microbes Infect. 2020 Dec;9(1):796-812,sunb@ustc.edu.cn,Rsp has no influence on the virulence of S.aureus ?agr strain in a subcutaneous abscess model of mice.,B Liu 2020,2020,2 genes,Liu-2020-Rsp promotes the transcription of vir,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16311,PHI:10372,UniProt,P0A0I7,GenBank,AAA26597,,,,Agr,,,,,,,1280,Staphylococcus aureus,93061,NCTC 8325,nosocomial infection; abscess; skin lesion,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,accessory gene regulator protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32248753,PubMed,10.1080/22221751.2020.1752116,Emerg Microbes Infect. 2020 Dec;9(1):796-812,sunb@ustc.edu.cn,Rsp has no influence on the virulence of S.aureus ?agr strain in a subcutaneous abscess model of mice.,B Liu 2020,2020,2 genes,Liu-2020-Rsp promotes the transcription of vir,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16312,PHI:10371,UniProt,A0A6B0BLK0,GenBank,MVI56578,,,S_4031.LGMP.AI,Rsp,,,,,,PHI:10372,1280,Staphylococcus aureus,93061,NCTC 8325,nosocomial infection; abscess; skin lesion,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,AraC family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32248753,PubMed,10.1080/22221751.2020.1752116,Emerg Microbes Infect. 2020 Dec;9(1):796-812,sunb@ustc.edu.cn,Rsp has no influence on the virulence of S.aureus ?agr strain in a subcutaneous abscess model of mice.,B Liu 2020,2020,2 genes,Liu-2020-Rsp promotes the transcription of vir,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16313,PHI:10372,UniProt,P0A0I7,GenBank,AAA26597,,,,Agr,,,,,,PHI:10371,1280,Staphylococcus aureus,93061,NCTC 8325,nosocomial infection; abscess; skin lesion,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,accessory gene regulator protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32248753,PubMed,10.1080/22221751.2020.1752116,Emerg Microbes Infect. 2020 Dec;9(1):796-812,sunb@ustc.edu.cn,Rsp has no influence on the virulence of S.aureus ?agr strain in a subcutaneous abscess model of mice.,B Liu 2020,2020,2 genes,Liu-2020-Rsp promotes the transcription of vir,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16314,PHI:10373,UniProt,no data found,GenBank,AVN87035,,,D39V,Pde1,,,,,,,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage cell line,DHH family phosphoesterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16315,PHI:10374,UniProt,no data found,GenBank,AVN86254,,,D39V,Pde2,,,,,,,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage cell line,DHH family phosphoesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16316,PHI:10373,UniProt,no data found,GenBank,AVN87035,,,D39V,Pde1,,,,,,PHI:10374,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage cell line,DHH family phosphoesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16317,PHI:10374,UniProt,no data found,GenBank,AVN86254,,,D39V,Pde2,,,,,,PHI:10373,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage cell line,DHH family phosphoesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16318,PHI:10373,UniProt,no data found,GenBank,AVN87035,,,D39V,Pde1,,,,,,,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,alveolar macrophage; lung,DHH family phosphoesterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16319,PHI:10374,UniProt,no data found,GenBank,AVN86254,,,D39V,Pde2,,,,,,,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,alveolar macrophage; lung,DHH family phosphoesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16320,PHI:10373,UniProt,no data found,GenBank,AVN87035,,,D39V,Pde1,,,,,,PHI:10374,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,alveolar macrophage; lung,DHH family phosphoesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16321,PHI:10374,UniProt,no data found,GenBank,AVN86254,,,D39V,Pde2,,,,,,PHI:10373,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,alveolar macrophage; lung,DHH family phosphoesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16322,PHI:10373,UniProt,no data found,GenBank,AVN87035,,,D39V,Pde1,,,,,,,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,DHH family phosphoesterase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16323,PHI:10374,UniProt,no data found,GenBank,AVN86254,,,D39V,Pde2,,,,,,,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,DHH family phosphoesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16324,PHI:10373,UniProt,no data found,GenBank,AVN87035,,,D39V,Pde1,,,,,,PHI:10374,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,DHH family phosphoesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16325,PHI:10374,UniProt,no data found,GenBank,AVN86254,,,D39V,Pde2,,,,,,PHI:10373,1313,Streptococcus pneumoniae,,,pneumococcal pneumonia,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage cell line,DHH family phosphoesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,stronger defence response,gene deletion: full,,,YVS,32300347,PubMed,10.3389/fimmu.2020.00554,Front Immunol. 2020 Mar 31;11:554,jmizgerd@bu.edu,Macrophage hyperactivation by Pde2-deficient pneumococci led to rapid cell death.,A K Wooten 2020,2020,2 genes,Wooten-2020-Unique Roles for Streptococcus pne,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16326,PHI:10375,UniProt,G4N2V4,GenBank,EHA53403,,,70-15,LAEA (MGG_07964),,,,MoVeA,UniProt: G4N5X8; GenBank: EHA49754,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. HR12,,,leaf,global regulator of secondary metabolism,,,,unaffected pathogenicity,,,,,,reduced,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,32238572,PubMed,10.1128/mSphere.00936-19,mSphere. 2020 Apr 1;5(2):e00936-19,subhankar.roybarman@bt.nitdgp.ac.in,"Overexpression of MoLAEA increased penicillin G production, whereas the silenced strain showed a complete absence of penicillin G compared to its presence in the wild type.",P Saha 2020,2020,1 gene,Saha-2020-MoLAEA Regulates Secondary Metabolis,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16327,PHI:10375,UniProt,G4N2V4,GenBank,EHA53403,,,70-15,LAEA (MGG_07964),,,,MoVeA,UniProt: G4N5X8; GenBank: EHA49754,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. HR12,,,leaf,global regulator of secondary metabolism,,,,unaffected pathogenicity,,,,,,increased,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32238572,PubMed,10.1128/mSphere.00936-19,mSphere. 2020 Apr 1;5(2):e00936-19,subhankar.roybarman@bt.nitdgp.ac.in,"Overexpression of MoLAEA increased penicillin G production, whereas the silenced strain showed a complete absence of penicillin G compared to its presence in the wild type.",P Saha 2020,2020,1 gene,Saha-2020-MoLAEA Regulates Secondary Metabolis,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16328,PHI:10376,UniProt,Q8X482,GenBank,AE005419_8,,,EDL933,espFu,,,,,,,562,Escherichia coli,,BA320,acute diarrhea,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,gene deletion: full; gene complementation,,,YVS,32291304,PubMed,10.1128/mBio.00617-20,mBio. 2020 Apr 14;11(2):e00617-20,vanessa.sperandio@utsouthwestern.edu waldir.elias@butantan.gov.br,EspFu promoted actin remodeling and bacterial attachment to epithelial cells.,F H Martins 2020,2020,2 genes,Martins-2020-EspFu-Mediated Actin Assembly Enh,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16329,PHI:10377,UniProt,B7UM99,GenBank,AAB88410,,,E2348/69,Tir,,,,,,,562,Escherichia coli,,BA320,acute diarrhea,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,gene deletion: full; gene complementation,,,YVS,32291304,PubMed,10.1128/mBio.00617-20,mBio. 2020 Apr 14;11(2):e00617-20,vanessa.sperandio@utsouthwestern.edu waldir.elias@butantan.gov.br,EspFu promoted actin remodeling and bacterial attachment to epithelial cells.,F H Martins 2020,2020,2 genes,Martins-2020-EspFu-Mediated Actin Assembly Enh,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16330,PHI:10376,UniProt,Q8X482,GenBank,AE005419_8,,,EDL933,espFu,,,,,,PHI:10377,562,Escherichia coli,,BA320,acute diarrhea,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,gene deletion: full; gene complementation,,,YVS,32291304,PubMed,10.1128/mBio.00617-20,mBio. 2020 Apr 14;11(2):e00617-20,vanessa.sperandio@utsouthwestern.edu waldir.elias@butantan.gov.br,EspFu promoted actin remodeling and bacterial attachment to epithelial cells.,F H Martins 2020,2020,2 genes,Martins-2020-EspFu-Mediated Actin Assembly Enh,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16331,PHI:10377,UniProt,B7UM99,GenBank,AAB88410,,,E2348/69,Tir,,,,,,PHI:10376,562,Escherichia coli,,BA320,acute diarrhea,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,gene deletion: full; gene complementation,,,YVS,32291304,PubMed,10.1128/mBio.00617-20,mBio. 2020 Apr 14;11(2):e00617-20,vanessa.sperandio@utsouthwestern.edu waldir.elias@butantan.gov.br,EspFu promoted actin remodeling and bacterial attachment to epithelial cells.,F H Martins 2020,2020,2 genes,Martins-2020-EspFu-Mediated Actin Assembly Enh,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16332,PHI:10378,UniProt,G2XF49,GenBank,EGY18447,,,VdLs.17,Dpb4 (VDAG_08781),chromosome 1,,,Isw2,UniProt: G2WUQ0; GenBank: EGY17841,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,hypothetical protein,,,,reduced virulence,,no,no,,,reduced; aberrant,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32298394,PubMed,10.1371/journal.ppat.1008481,PLoS Pathog. 2020 Apr 16;16(4):e1008481,guohs@im.ac.cn,A knockout mutant of either VdDpb4 or VdIsw2 reduced the efficiency of DNA repair in the presence of DNA-dam-aging agents and virulence during plant infection.,S Wang 2020,2020,2 genes,Wang-2020-Verticillium dahliae chromatin remod,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16333,PHI:10378,UniProt,G2XF49,GenBank,EGY18447,,,VdLs.17,Dpb4 (VDAG_08781),chromosome 1,,,Isw2,UniProt: G2WUQ0; GenBank: EGY17841,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,hypothetical protein,,,,reduced virulence,,no,no,,,aberrant; reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32298394,PubMed,10.1371/journal.ppat.1008481,PLoS Pathog. 2020 Apr 16;16(4):e1008481,guohs@im.ac.cn,A knockout mutant of either VdDpb4 or VdIsw2 reduced the efficiency of DNA repair in the presence of DNA-dam-aging agents and virulence during plant infection.,S Wang 2020,2020,2 genes,Wang-2020-Verticillium dahliae chromatin remod,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16334,PHI:10379,UniProt,G2WUQ0,GenBank,EGY17841,,,VdLs.17,Isw2,chromosome 1,,,Dpb4,UniProt: G2XF49; GenBank: EGY18447,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,ISWI chromatin-remodeling complex ATPase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32298394,PubMed,10.1371/journal.ppat.1008481,PLoS Pathog. 2020 Apr 16;16(4):e1008481,guohs@im.ac.cn,A knockout mutant of either VdDpb4 or VdIsw2 reduced the efficiency of DNA repair in the presence of DNA-dam-aging agents and virulence during plant infection.,S Wang 2020,2020,2 genes,Wang-2020-Verticillium dahliae chromatin remod,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16335,PHI:10379,UniProt,G2WUQ0,GenBank,EGY17841,,,VdLs.17,Isw2,chromosome 1,,,Dpb4,UniProt: G2XF49; GenBank: EGY18447,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf,ISWI chromatin-remodeling complex ATPase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32298394,PubMed,10.1371/journal.ppat.1008481,PLoS Pathog. 2020 Apr 16;16(4):e1008481,guohs@im.ac.cn,A knockout mutant of either VdDpb4 or VdIsw2 reduced the efficiency of DNA repair in the presence of DNA-dam-aging agents and virulence during plant infection.,S Wang 2020,2020,2 genes,Wang-2020-Verticillium dahliae chromatin remod,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16336,PHI:10380,UniProt,A3M645,GenBank,ABO12389,,,ATCC 17978,RecA,,,,A1S_2813,UniProt: no data found; GenBank: APP29846,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,DNA strand exchange and recombination protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32255384,PubMed,10.1080/21505594.2020.1748923,Virulence. 2020 Dec;11(1):315-326,jesus.aranda@uab.cat,RecA and CheW-like proteins were involved in the surface-associated motility and chemotaxis of A. baumannii strain ATCC 17978.,J Corral 2020,2020,2 genes,Corral-2020-Direct interaction between RecA an,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16337,PHI:10380,UniProt,A3M645,GenBank,ABO12389,,,ATCC 17978,RecA,,,,A1S_2813,UniProt: no data found; GenBank: APP29846,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,DNA strand exchange and recombination protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32255384,PubMed,10.1080/21505594.2020.1748923,Virulence. 2020 Dec;11(1):315-326,jesus.aranda@uab.cat,RecA and CheW-like proteins were involved in the surface-associated motility and chemotaxis of A. baumannii strain ATCC 17978.,J Corral 2020,2020,2 genes,Corral-2020-Direct interaction between RecA an,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16338,PHI:10381,UniProt,no data found,GenBank,APP29846,,,ATCC 17978,A1S_2813 (AUO97_03055),,,,RecA,UniProt: A3M645; GenBank: ABO12389,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,twitching motility protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32255384,PubMed,10.1080/21505594.2020.1748923,Virulence. 2020 Dec;11(1):315-326,jesus.aranda@uab.cat,RecA and CheW-like proteins were involved in the surface-associated motility and chemotaxis of A. baumannii strain ATCC 17978.,J Corral 2020,2020,2 genes,Corral-2020-Direct interaction between RecA an,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16339,PHI:10381,UniProt,no data found,GenBank,APP29846,,,ATCC 17978,A1S_2813 (AUO97_03055),,,,RecA,UniProt: A3M645; GenBank: ABO12389,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,twitching motility protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32255384,PubMed,10.1080/21505594.2020.1748923,Virulence. 2020 Dec;11(1):315-326,jesus.aranda@uab.cat,RecA and CheW-like proteins were involved in the surface-associated motility and chemotaxis of A. baumannii strain ATCC 17978.,J Corral 2020,2020,2 genes,Corral-2020-Direct interaction between RecA an,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16340,PHI:10382,UniProt,no data found,GenBank,ALF89517,,,UY031,RipI,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient overexpression,,,YVS,32285606,PubMed,10.1111/mpp.12937,Mol Plant Pathol. 2020 Jul;21(7):999-1004,hszou@fafu.edu.cn,"Transient overexpression of RipI induces the hypersensitive response (HR), up-regulating the HR marker gene hin1, in Nicotiana benthamiana.",T Zhuo 2020,2020,1 gene,Zhuo-2020-The Ralstonia solanacearum effector,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16341,PHI:10382,UniProt,no data found,GenBank,ALF89517,,,UY031,RipI,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32285606,PubMed,10.1111/mpp.12937,Mol Plant Pathol. 2020 Jul;21(7):999-1004,hszou@fafu.edu.cn,Deletion of R. solanacearum ripI led to increased virulence in tomato (Solanum lycopersicum) plants.,T Zhuo 2020,2020,1 gene,Zhuo-2020-The Ralstonia solanacearum effector,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16342,PHI:10383,UniProt,Q8P9D0,GenBank,AAM41224,,,ATCC 33913,RpoN2 (XCC1935),,,,,,,339,Xanthomonas campestris,,pv. campestris strain Xc1,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,RNA polymerase sigma-54 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32281725,PubMed,10.1111/mpp.12938,Mol Plant Pathol. 2020 Jul;21(7):907-922,wanghh36@scau.edu.cn,"RpoN2, but not rpoN1, was required for the virulence of X. campestris.",K Li 2020,2020,2 genes,Li-2020-RpoN1 and RpoN2 play different regulat,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16343,PHI:10384,UniProt,Q8P712,GenBank,AAM42074,,,ATCC 33913,RpoN1 (XCC2802),,,,,,,339,Xanthomonas campestris,,pv. campestris strain Xc1,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,RNA polymerase sigma-54 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32281725,PubMed,10.1111/mpp.12938,Mol Plant Pathol. 2020 Jul;21(7):907-922,wanghh36@scau.edu.cn,"RpoN2, but not rpoN1, was required for the virulence of X. campestris.",K Li 2020,2020,2 genes,Li-2020-RpoN1 and RpoN2 play different regulat,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16344,PHI:10383,UniProt,Q8P9D0,GenBank,AAM41224,,,ATCC 33913,RpoN2 (XCC1935),,,,,,PHI:10384,339,Xanthomonas campestris,,pv. campestris strain Xc1,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,RNA polymerase sigma-54 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32281725,PubMed,10.1111/mpp.12938,Mol Plant Pathol. 2020 Jul;21(7):907-922,wanghh36@scau.edu.cn,"RpoN2, but not rpoN1, was required for the virulence of X. campestris.",K Li 2020,2020,2 genes,Li-2020-RpoN1 and RpoN2 play different regulat,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16345,PHI:10384,UniProt,Q8P712,GenBank,AAM42074,,,ATCC 33913,RpoN1 (XCC2802),,,,,,PHI:10383,339,Xanthomonas campestris,,pv. campestris strain Xc1,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,RNA polymerase sigma-54 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32281725,PubMed,10.1111/mpp.12938,Mol Plant Pathol. 2020 Jul;21(7):907-922,wanghh36@scau.edu.cn,"RpoN2, but not rpoN1, was required for the virulence of X. campestris.",K Li 2020,2020,2 genes,Li-2020-RpoN1 and RpoN2 play different regulat,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16346,PHI:10385,UniProt,S3MI24,GenBank,EPF66103,,,SM,pvdD,,,,,,,317,Pseudomonas syringae,,MB03,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,pyoverdine side chain non-ribosomal peptide synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,YVS,32235814,PubMed,10.3390/ijms21062198,Int J Mol Sci. 2020 Mar 22;21(6):2198,lilin@mail.hzau.edu.cn,Mutant strains showed abrogated pyoverdine production and attenuated virulence against C. elegans.,A Bashir 2020,2020,2 genes,Bashir-2020-Pyoverdine-Mediated Killing of Cae,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16347,PHI:10386,UniProt,S3MF12,GenBank,EPF66102,,,SM,pvdJ,,,,,,,317,Pseudomonas syringae,,MB03,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,pyoverdine side chain non-ribosomal peptide synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption; gene complementation,,,YVS,32235814,PubMed,10.3390/ijms21062198,Int J Mol Sci. 2020 Mar 22;21(6):2198,lilin@mail.hzau.edu.cn,Mutant strains showed abrogated pyoverdine production and attenuated virulence against C. elegans.,A Bashir 2020,2020,2 genes,Bashir-2020-Pyoverdine-Mediated Killing of Cae,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16348,PHI:10387,UniProt,A0A6C7HPB2,GenBank,CAR33117,,,P125109,SEN1538,,,,,,,28901,Salmonella enterica,550537,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,mesenteric lymph node; spleen; cecum; liver,conserved hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32193977,PubMed,10.1080/21505594.2020.1743540,Virulence. 2020 Dec;11(1):295-314,msuar@kiitbiotech.ac.in,"When SEN1538 was deleted, the pathogen showed reduced survival during antimicrobial peptide introduction and heat stress at 55°C compared to WT.",A Arunima 2020,2020,1 gene,Arunima-2020-RpoS-regulated SEN1538 gene promo,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16349,PHI:10387,UniProt,A0A6C7HPB2,GenBank,CAR33117,,,P125109,SEN1538,,,,,,,28901,Salmonella enterica,550537,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,colon epithelial cell,conserved hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32193977,PubMed,10.1080/21505594.2020.1743540,Virulence. 2020 Dec;11(1):295-314,msuar@kiitbiotech.ac.in,"When SEN1538 was deleted, the pathogen showed reduced survival during antimicrobial peptide introduction and heat stress at 55°C compared to WT.",A Arunima 2020,2020,1 gene,Arunima-2020-RpoS-regulated SEN1538 gene promo,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16350,PHI:10387,UniProt,A0A6C7HPB2,GenBank,CAR33117,,,P125109,SEN1538,,,,,,,28901,Salmonella enterica,550537,subsp. enterica serovar Enteritidis strain P125109,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,conserved hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32193977,PubMed,10.1080/21505594.2020.1743540,Virulence. 2020 Dec;11(1):295-314,msuar@kiitbiotech.ac.in,"When SEN1538 was deleted, the pathogen showed reduced survival during antimicrobial peptide introduction and heat stress at 55°C compared to WT.",A Arunima 2020,2020,1 gene,Arunima-2020-RpoS-regulated SEN1538 gene promo,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16351,PHI:10388,UniProt,I1RC79,GenBank,XP_011316954,,,PH-1; NRRL 31084,FCT1 (FGSG_01182),chromosome 1,,,FCT2 (FGSG_05304),UniProt: I1RMV4; GenBank: XP_011323816,,5518,Fusarium graminearum,449239,Z-3639,head blight (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,CCAAT-binding transcription factor,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32184445,PubMed,10.1038/s41598-020-61885-4,Sci Rep. 2020 Mar 17;10(1):4898,hogongi7@snu.ac.kr,FCT1 and FCT2 were important for virulence and total trichothecene production.,J E Kim 2020,2020,2 genes,Kim-2020-Characterization of the CCAAT-binding,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16352,PHI:10389,UniProt,I1RMV4,GenBank,XP_011323816,,,PH-1; NRRL 31084,FCT2 (FGSG_05304),chromosome 3,,,FCT1 (FGSG_01182),UniProt: I1RC79; GenBank: XP_011316954,,5518,Fusarium graminearum,449239,Z-3639,head blight (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,CCAAT-binding transcription factor,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32184445,PubMed,10.1038/s41598-020-61885-4,Sci Rep. 2020 Mar 17;10(1):4898,hogongi7@snu.ac.kr,FCT1 and FCT2 were important for virulence and total trichothecene production.,J E Kim 2020,2020,2 genes,Kim-2020-Characterization of the CCAAT-binding,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16353,PHI:10390,UniProt,Q9HYN5,GenBank,AE004758_6,,,PAO1,lecB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,carnivores,9612,Canis lupus (related: gray wolf),subsp. familiaris MDCK cell line,,,MDCK cell,lectin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32156827,PubMed,10.1128/mBio.03260-19,mBio. 2020 Mar 10;11(2):e03260-19,winfried.roemer@bioss.uni-freiburg.de,Knockout of LecB significantly reduced crawling events.,R Thuenauer 2020,2020,1 gene,Thuenauer-2020-The Pseudomonas aeruginosa Lect,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16354,PHI:10391,UniProt,A0A0D5YLV4,GenBank,AKA32929,,,AB5075-UW,pcoB (ABUW_3227),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,copper resistance protein B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32117089,PubMed,10.3389/fmicb.2020.00016,Front Microbiol. 2020 Feb 6;11:16,dmerrell@usuhs.mil,"Copper possessed antimicrobial activity against multidrug-resistant A. baumannii, and copper sensitivity was further increased when copper homeostasis mechanisms were interrupted.",C L Williams 2020,2020,8 genes,Williams-2020-Characterization of Acinetobacte,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16355,PHI:10392,UniProt,A0A0D5YKR5,GenBank,AKA32930,,,AB5075-UW,pcoA (ABUW_3228),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,copper resistance protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32117089,PubMed,10.3389/fmicb.2020.00016,Front Microbiol. 2020 Feb 6;11:16,dmerrell@usuhs.mil,"Copper possessed antimicrobial activity against multidrug-resistant A. baumannii, and copper sensitivity was further increased when copper homeostasis mechanisms were interrupted.",C L Williams 2020,2020,8 genes,Williams-2020-Characterization of Acinetobacte,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16356,PHI:10393,UniProt,A0A0D5YLC8,GenBank,AKA33017,,,AB5075-UW,cueO (ABUW_3321),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,copper resistance protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32117089,PubMed,10.3389/fmicb.2020.00016,Front Microbiol. 2020 Feb 6;11:16,dmerrell@usuhs.mil,"Copper possessed antimicrobial activity against multidrug-resistant A. baumannii, and copper sensitivity was further increased when copper homeostasis mechanisms were interrupted.",C L Williams 2020,2020,8 genes,Williams-2020-Characterization of Acinetobacte,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16357,PHI:10394,UniProt,A0A090BEA2,GenBank,AKA33020,,,AB5075-UW,cusS (ABUW_3324),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sensor kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32117089,PubMed,10.3389/fmicb.2020.00016,Front Microbiol. 2020 Feb 6;11:16,dmerrell@usuhs.mil,"Copper possessed antimicrobial activity against multidrug-resistant A. baumannii, and copper sensitivity was further increased when copper homeostasis mechanisms were interrupted.",C L Williams 2020,2020,8 genes,Williams-2020-Characterization of Acinetobacte,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16358,PHI:10395,UniProt,A0A090B6B0,GenBank,AKA33023,,,AB5075-UW,copD (ABUW_3327),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,copper resistance D,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32117089,PubMed,10.3389/fmicb.2020.00016,Front Microbiol. 2020 Feb 6;11:16,dmerrell@usuhs.mil,"Copper possessed antimicrobial activity against multidrug-resistant A. baumannii, and copper sensitivity was further increased when copper homeostasis mechanisms were interrupted.",C L Williams 2020,2020,8 genes,Williams-2020-Characterization of Acinetobacte,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16359,PHI:10396,UniProt,A0A090C282,GenBank,AKA33016,,,AB5075-UW,copB (ABUW_3320),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,autotransporter domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32117089,PubMed,10.3389/fmicb.2020.00016,Front Microbiol. 2020 Feb 6;11:16,dmerrell@usuhs.mil,"Copper possessed antimicrobial activity against multidrug-resistant A. baumannii, and copper sensitivity was further increased when copper homeostasis mechanisms were interrupted.",C L Williams 2020,2020,8 genes,Williams-2020-Characterization of Acinetobacte,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16360,PHI:10397,UniProt,A0A090B8T6,GenBank,AKA33019,,,AB5075-UW,cusR (ABUW_3323),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DNA-binding response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32117089,PubMed,10.3389/fmicb.2020.00016,Front Microbiol. 2020 Feb 6;11:16,dmerrell@usuhs.mil,"Copper possessed antimicrobial activity against multidrug-resistant A. baumannii, and copper sensitivity was further increased when copper homeostasis mechanisms were interrupted.",C L Williams 2020,2020,8 genes,Williams-2020-Characterization of Acinetobacte,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16361,PHI:10398,UniProt,A0A090BCG3,GenBank,AKA33022,,,AB5075-UW,copC (ABUW_3326),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,copper resistance protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32117089,PubMed,10.3389/fmicb.2020.00016,Front Microbiol. 2020 Feb 6;11:16,dmerrell@usuhs.mil,"Copper possessed antimicrobial activity against multidrug-resistant A. baumannii, and copper sensitivity was further increased when copper homeostasis mechanisms were interrupted.",C L Williams 2020,2020,8 genes,Williams-2020-Characterization of Acinetobacte,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16362,PHI:10397,UniProt,A0A090B8T6,GenBank,AKA33019,,,AB5075-UW,cusR (ABUW_3323),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,DNA-binding response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32117089,PubMed,10.3389/fmicb.2020.00016,Front Microbiol. 2020 Feb 6;11:16,dmerrell@usuhs.mil,"Copper possessed antimicrobial activity against multidrug-resistant A. baumannii, and copper sensitivity was further increased when copper homeostasis mechanisms were interrupted.",C L Williams 2020,2020,8 genes,Williams-2020-Characterization of Acinetobacte,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16363,PHI:10395,UniProt,A0A090B6B0,GenBank,AKA33023,,,AB5075-UW,copD (ABUW_3327),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,copper resistance D,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32117089,PubMed,10.3389/fmicb.2020.00016,Front Microbiol. 2020 Feb 6;11:16,dmerrell@usuhs.mil,"Copper possessed antimicrobial activity against multidrug-resistant A. baumannii, and copper sensitivity was further increased when copper homeostasis mechanisms were interrupted.",C L Williams 2020,2020,8 genes,Williams-2020-Characterization of Acinetobacte,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16364,PHI:10399,UniProt,J9VP29,GenBank,AFR95191,,,H99,mrj1 (CNAG_00938),chromosome 5,,,,,,5207,Cryptococcus neoformans,1298968,H99,systemic cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; kidney; brain; lung; blood,mitochondrial co-chaperone,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32518190,PubMed,10.1128/mBio.01127-20,mBio. 2020 Jun 9;11(3):e01127-20,kronstad@msl.ubc.ca,"The mrj1 mutants were deficient in mitochondrial functions, including growth on alternative carbon sources, growth without iron, and mitochondrial polarization.",L C Horianopoulos 2020,2020,1 gene,Horianopoulos-2020-The Novel J-Domain Protein,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16365,PHI:10400,UniProt,Q6XVV0,GenBank,AAP79030,,,,Sfgtr4 (ORF186),,,,SfpdgA,UniProt: no data found; GenBank: no data found,,623,Shigella flexneri,,M90T-Sm,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,putative lipopolysaccharides (LPS) glycosyltransferase (Gtr),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32512756,PubMed,10.3390/microorganisms8060841,Microorganisms. 2020 Jun 4;8(6):E841,abdelmoughit.kaoukab@gmail.com,"Sfgtr4 mutant significantly reduced HeLa cells invasion without impairing type III effectors secretion, increased susceptibility to lysozyme degradation, and enhanced bacterial killing by polymorphonuclear neutrophils (PMNs).",A Kaoukab-Raji 2020,2020,2 genes,Kaoukab-Raji-2020-Inactivation of the sfgtr4 G,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16366,PHI:10400,UniProt,Q6XVV0,GenBank,AAP79030,,,,Sfgtr4 (ORF186),,,,SfpdgA,UniProt: no data found; GenBank: no data found,PHI:10401,623,Shigella flexneri,,M90T-Sm,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,putative lipopolysaccharides (LPS) glycosyltransferase (Gtr),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32512756,PubMed,10.3390/microorganisms8060841,Microorganisms. 2020 Jun 4;8(6):E841,abdelmoughit.kaoukab@gmail.com,"Sfgtr4 mutant significantly reduced HeLa cells invasion without impairing type III effectors secretion, increased susceptibility to lysozyme degradation, and enhanced bacterial killing by polymorphonuclear neutrophils (PMNs).",A Kaoukab-Raji 2020,2020,2 genes,Kaoukab-Raji-2020-Inactivation of the sfgtr4 G,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16367,PHI:10401,,no data found,GenBank,EIQ77839,,,1236-66,SfpgdA,,,,Sfgtr4,UniProt: Q6XVV0; GenBank: AAP79030,PHI:10400,623,Shigella flexneri,,M90T-Sm,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,peptidoglycan deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32512756,PubMed,10.3390/microorganisms8060841,Microorganisms. 2020 Jun 4;8(6):E841,abdelmoughit.kaoukab@gmail.com,"Sfgtr4 mutant significantly reduced HeLa cells invasion without impairing type III effectors secretion, increased susceptibility to lysozyme degradation, and enhanced bacterial killing by polymorphonuclear neutrophils (PMNs).",A Kaoukab-Raji 2020,2020,2 genes,Kaoukab-Raji-2020-Inactivation of the sfgtr4 G,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16368,PHI:10402,,no data found,,,,,,PcPdeH (Pc_511692),,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,high-affinity phosphodiesterase,,,cAMP signaling pathway,reduced virulence,,,,yes,,,,reduced; aberrant,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,32220377,PubMed,10.1016/j.funbio.2020.01.006,Fungal Biol. Mar-Apr 2020;124(3-4):164-173,dyzhang78@163.com,The knockout transformants of PcPdeH showed vegetative growth defects and abnormal cyst germination.,X Li 2020,2020,1 gene,Li-2020-The high-affinity phosphodiesterase Pc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16369,PHI:10402,,no data found,,,,,,PcPdeH (Pc_511692),,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,high-affinity phosphodiesterase,,,cAMP signaling pathway,reduced virulence,,,,yes,,,,reduced; aberrant,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,32220377,PubMed,10.1016/j.funbio.2020.01.006,Fungal Biol. Mar-Apr 2020;124(3-4):164-173,dyzhang78@163.com,The knockout transformants of PcPdeH showed vegetative growth defects and abnormal cyst germination.,X Li 2020,2020,1 gene,Li-2020-The high-affinity phosphodiesterase Pc,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16370,PHI:10403,,no data found,,,,,,ittA,,,,,,,139,Borreliella burgdorferi,,ML23,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,ear; skin; deep inguinal lymph node; heart; bladder; tibiotarsal joint,intergenic trans-acting small non-coding RNA,,,,reduced virulence,,,,,,,,,,no,gentamicin; streptomycin,gentamicin: CHEBI:17833; streptomycin: CHEBI:17076,,,,,gene deletion: full; gene complementation,,,YVS,32365143,PubMed,10.1371/journal.ppat.1008423,PLoS Pathog.2020 May 4;16(5):e1008423,jskare@tamu.edu,"The genetic inactivation of ittA resulted in a significant attenuation in infectivity, with decreased spirochetal load in ear, heart, skin and joint tissues.",D N Medina-Perez 2020,2020,1 gene,Medina-Perez-2020-The intergenic small non-cod,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16371,PHI:10404,UniProt,A0A0A2JAN7,GenBank,XP_016595169,,,MD-8,SntB,,,,,,,27334,Penicillium expansum,,Pe-21,blue rot,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,"zinc finger, PHD-type, histone modifying protein",,,,reduced virulence,,,,,,reduced,,reduced; aberrant,increased,no,hygromycin B,hygromycin B: CHEBI:16976,,,,,gene deletion: full; gene complementation,,,YVS,32328048,PubMed,10.3389/fmicb.2020.00610,Front Microbiol.2020 Apr 9;11:610,npkeller@wisc.edu,"Deletion of sntB in P. expansum resulted in several phenotypic changes in the fungus including stunted vegetative growth, reduced conidiation, but enhanced germination rates as well as decreased virulence on Golden Delicious apples.",J Tannous 2020,2020,1 gene,Tannous-2020-New Insight Into Pathogenicity an,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16372,PHI:10405,UniProt,Q4WUE0,GenBank,EAL91786,,,Af293,ArgJ (AFUA_5G08120),chromosome 5,,,,,,746128,Aspergillus fumigatus,,AfS77,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"arginine biosynthesis bifunctional protein ArgJ, mitochondrial",,,arginine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32326414,PubMed,10.3390/genes11040423,Genes (Basel).2020 Apr 15;11(4):423,hubertus.haas@i-med.ac.at,Inactivation of either ArgJ or ArgB resulted in arginine auxotrophy.,A M Dietl 2020,2020,2 genes,Dietl-2020-Arginine Auxotrophy Affects Siderop,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16373,PHI:10406,UniProt,Q4WNW5,GenBank,EAL90069,,,Af293,ArgB (AFUA_4G07190),chromosome 4,,,,,,746128,Aspergillus fumigatus,,AfS77,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,ornithine carbamoyltransferase,,,arginine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32326414,PubMed,10.3390/genes11040423,Genes (Basel).2020 Apr 15;11(4):423,hubertus.haas@i-med.ac.at,Inactivation of either ArgJ or ArgB resulted in arginine auxotrophy.,A M Dietl 2020,2020,2 genes,Dietl-2020-Arginine Auxotrophy Affects Siderop,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16374,PHI:10405,UniProt,Q4WUE0,GenBank,EAL91786,,,Af293,ArgJ (AFUA_5G08120),chromosome 5,,,,,,746128,Aspergillus fumigatus,,AfS77,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,"arginine biosynthesis bifunctional protein ArgJ, mitochondrial",,,arginine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32326414,PubMed,10.3390/genes11040423,Genes (Basel).2020 Apr 15;11(4):423,hubertus.haas@i-med.ac.at,Inactivation of either ArgJ or ArgB resulted in arginine auxotrophy.,A M Dietl 2020,2020,2 genes,Dietl-2020-Arginine Auxotrophy Affects Siderop,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16375,PHI:10406,UniProt,Q4WNW5,GenBank,EAL90069,,,Af293,ArgB (AFUA_4G07190),chromosome 4,,,,,,746128,Aspergillus fumigatus,,AfS77,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,ornithine carbamoyltransferase,,,arginine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32326414,PubMed,10.3390/genes11040423,Genes (Basel).2020 Apr 15;11(4):423,hubertus.haas@i-med.ac.at,Inactivation of either ArgJ or ArgB resulted in arginine auxotrophy.,A M Dietl 2020,2020,2 genes,Dietl-2020-Arginine Auxotrophy Affects Siderop,BATCH_101A,2020-06-01,MC,,,,,,,,,,,,,
,,Record 16376,PHI:10407,UniProt,J5K7R4,GenBank,EJP70161,,,ARSEF 2860,RAD23 (BBA_01030),,,,phr2,UniProt: J4WK53; GenBank: EJP70165,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,UV excision repair protein,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,,no,hydroxyurea; camptothecin; H2O2; menadione; NaCl; sorbitol; Congo red; calcofluor white,hydroxyurea: CHEBI:44423; camptothecin: CHEBI:27656; H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion full; gene complementation,,,YVS,32245759,PubMed,10.1128/AEM.00287-20,Appl Environ Microbiol. 2020 May 19;86(11):e00287-20. doi: 10.1128/AEM.00287-20. Print 2020 May 19,mgfeng@zju.edu.cn,"The deletion mutant was severely compromised in radial growth, conidiation, conidial quality, virulence, multiple stress tolerance, and transcriptional expression of many phenotype-related genes.",D Y Wang 2020,2020,1 gene,Wang-2020-Photoprotective Role of Photolyase-I,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16377,PHI:10408,UniProt,A6H110,GenBank,CAL44034,,,JIP02/86,gldN,,,,,,,96345,Flavobacterium psychrophilum,,OSU THCO2-90,bacterial cold-water disease,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,gill; spleen,gliding motility protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32532872,PubMed,10.1128/AEM.00799-20,Appl Environ Microbiol. 2020 Jun 12:AEM.00799-20. doi: 10.1128/AEM.00799-20. Online ahead of print,mcbride@uwm.edu,"The ΔgldN mutant was deficient in adhesion, gliding motility, and in extracellular proteolytic and hemolytic activities.",P Barbier 2020,2020,1 gene,Barbier-2020-The type IX secretion system is r,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16378,PHI:10409,UniProt,A0A3L8GGZ3,GenBank,RLU55934,,,QMA0445,MurI,,,,,,,1346,Streptococcus iniae,,HNM-1,bacteremia; cellulitis; meningitis; osteomyelitis,bony fishes,61970,Acipenser sinensis (related: Chinese sturgeon),,,,blood,glutamate racemase,,,,reduced virulence,,,,,,,,reduced,,no,hydroxylamine; DTT; EDTA,hydroxylamine: CHEBI:15429; DTT: CHEBI:42170; EDTA: CHEBI:64758,,,,,gene deletion: full,,,YVS,32093601,PubMed,10.1134/S0006297920020121,Biochemistry (Mosc). 2020 Feb;85(2):248-256. doi: 10.1134/S0006297920020121,pqw1234@163.com,MurI was found to be essential for the viability and cell wall integrity of S. iniae.,M Muhammad 2020,2020,1 gene,Muhammad-2020-Significance of Glutamate Racema,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16379,PHI:10410,UniProt,G2X6A8,GenBank,EGY14526,,,VdLs.17,VdTHI20,chromosome 4,,,,,,27337,Verticillium dahliae,,991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,root; leaf,phosphomethylpyrimidine kinase,,,pyrimidine biosynthesis,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32085660,PubMed,10.3390/ijms21041378,Int J Mol Sci. 2020 Feb 18;21(4):1378. doi: 10.3390/ijms21041378,wangqinglian666@gmail.com,"When the RNAi constructs of VdTHI20 were used to transform Nicotiana benthamiana, the transgenic lines expressing dsVdTHI20 showed elevated resistance to V. dahliae.",T Qin 2020,2020,1 gene,"Qin-2020-Verticillium dahliae VdTHI20, Involve",BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16380,PHI:10411,UniProt,G4N7R8,GenBank,EHA50073,,,70-15,UBP8 (MGG-03527),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ubiquitinyl hydrolase 1,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,reduced,no,NaCl; sorbitol; sodium dodecyl sulfate (SDS); H2O2; Congo red (CR),NaCl: CHEBI:26710; sorbitol: CHEBI:30911; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32274561,PubMed,10.1007/s00253-020-10572-5,Appl Microbiol Biotechnol. 2020 Jun;104(11):5081-5094. doi: 10.1007/s00253-020-10572-5. Epub 2020 Apr 9,lgd@fafu.edu.cn,"Reduced melanin in the ΔMoubp8 mutant is highly responsible for the attenuated pathogenicity since the appressoria of the ΔMoubp8 mutant was much more fragile than those of the wild type, due to the defective turgidity.",J Yang 2020,2020,1 gene,Yang-2020-The deubiquitinating enzyme MoUbp8 i,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16381,PHI:10411,UniProt,G4N7R8,GenBank,EHA50073,,,70-15,UBP8 (MGG-03527),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4513,Hordeum vulgare (related: barley),,,,plant epidermal cell,ubiquitinyl hydrolase 1,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,reduced,no,NaCl; sorbitol; sodium dodecyl sulfate (SDS); H2O2; Congo red (CR),NaCl: CHEBI:26710; sorbitol: CHEBI:30911; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32274561,PubMed,10.1007/s00253-020-10572-5,Appl Microbiol Biotechnol. 2020 Jun;104(11):5081-5094. doi: 10.1007/s00253-020-10572-5. Epub 2020 Apr 9,lgd@fafu.edu.cn,"Reduced melanin in the ΔMoubp8 mutant is highly responsible for the attenuated pathogenicity since the appressoria of the ΔMoubp8 mutant was much more fragile than those of the wild type, due to the defective turgidity.",J Yang 2020,2020,1 gene,Yang-2020-The deubiquitinating enzyme MoUbp8 i,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16382,PHI:10411,UniProt,G4N7R8,GenBank,EHA50073,,,70-15,UBP8 (MGG-03527),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4679,Allium cepa (related: onion),,,,plant epidermal cell,ubiquitinyl hydrolase 1,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,reduced,no,NaCl; sorbitol; sodium dodecyl sulfate (SDS); H2O2; Congo red (CR),NaCl: CHEBI:26710; sorbitol: CHEBI:30911; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; Congo red (CR): CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32274561,PubMed,10.1007/s00253-020-10572-5,Appl Microbiol Biotechnol. 2020 Jun;104(11):5081-5094. doi: 10.1007/s00253-020-10572-5. Epub 2020 Apr 9,lgd@fafu.edu.cn,"Reduced melanin in the ΔMoubp8 mutant is highly responsible for the attenuated pathogenicity since the appressoria of the ΔMoubp8 mutant was much more fragile than those of the wild type, due to the defective turgidity.",J Yang 2020,2020,1 gene,Yang-2020-The deubiquitinating enzyme MoUbp8 i,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16383,PHI:10412,UniProt,A0A172QB96,GenBank,QID98947,,,EX2016-02,SCD1,,,,,,,474922,Colletotrichum gloeosporioides,,EX2016-02,bitter rot,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. VF36,,,fruit; leaf,scytalone dehydratase,,,melanin synthesis,reduced virulence,,no,yes,yes,,,,wild type,wild type,no,,,,,,,gene deletion full; gene complementation,,,YVS,32093195,PubMed,10.3390/pathogens9020141,Pathogens. 2020 Feb 20;9(2):141. doi: 10.3390/pathogens9020141,lxu@bio.ecnu.edu.cn,"Decreased virulence of the DCgscd1 mutant was due to the damaged penetration ability of appressoria but that this was not related to turgor pressure, which was unchanged.",T Wang 2020,2020,1 gene,Wang-2020-CgSCD1 Is Essential for Melanin Bios,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16384,PHI:10412,UniProt,A0A172QB96,GenBank,QID98947,,,EX2016-02,SCD1,,,,,,,474922,Colletotrichum gloeosporioides,,EX2016-02,bitter rot,eudicots,159033,Citrus x aurantiifolia (related: lime),,,,fruit,scytalone dehydratase,,,melanin synthesis,reduced virulence,,no,yes,yes,,,,wild type,wild type,no,,,,,,,gene deletion full; gene complementation,,,YVS,32093195,PubMed,10.3390/pathogens9020141,Pathogens. 2020 Feb 20;9(2):141. doi: 10.3390/pathogens9020141,lxu@bio.ecnu.edu.cn,"Decreased virulence of the DCgscd1 mutant was due to the damaged penetration ability of appressoria but that this was not related to turgor pressure, which was unchanged.",T Wang 2020,2020,1 gene,Wang-2020-CgSCD1 Is Essential for Melanin Bios,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16385,PHI:10413,UniProt,P9WJ97,GenBank,CCP43071,,,H37Rv,Rv0341,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,isoniazid inductible gene protein,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,H2O2; SDS; diamide,H2O2: CHEBI:16240; SDS: CHEBI:8984; diamide: CHEBI:48958,,,,,heterologous expression,,,YVS,32521796,PubMed,10.3390/pathogens9060454,Pathogens. 2020 Jun 8;9(6):E454. doi: 10.3390/pathogens9060454,georgex@swu.edu.cn,Rv0341 expression increased Mycobacterium survival in macrophages.,A E Abdalla 2020,2020,1 gene,Abdalla-2020-Mycobacterium tuberculosis Rv0341,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16386,PHI:10413,UniProt,P9WJ97,GenBank,CCP43071,,,H37Rv,Rv0341,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,isoniazid inductible gene protein,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,H2O2; SDS; diamide,H2O2: CHEBI:16240; SDS: CHEBI:8984; diamide: CHEBI:48958,,,,,heterologous expression,,,YVS,32521796,PubMed,10.3390/pathogens9060454,Pathogens. 2020 Jun 8;9(6):E454. doi: 10.3390/pathogens9060454,georgex@swu.edu.cn,Rv0341 expression increased Mycobacterium survival in macrophages.,A E Abdalla 2020,2020,1 gene,Abdalla-2020-Mycobacterium tuberculosis Rv0341,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16387,PHI:10414,UniProt,F5ZP95,GenBank,AEF07105,,,UK-1,phoP,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,virulence transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32317368,PubMed,10.1126/scisignal.aaz3334,Sci Signal. 2020 Apr 21;13(628):eaaz3334. doi: 10.1126/scisignal.aaz3334,garciavescovi@ibr-conicet.gov.ar,The inability of the mutant phoP strain to disseminate systemically remained unchanged by CLA treatment.,M A Carabajal 2020,2020,1 gene,Carabajal-2020-PhoQ is an unsaturated fatty ac,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16388,PHI:10414,UniProt,F5ZP95,GenBank,AEF07105,,,UK-1,phoP,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,virulence transcriptional regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32317368,PubMed,10.1126/scisignal.aaz3334,Sci Signal. 2020 Apr 21;13(628):eaaz3334. doi: 10.1126/scisignal.aaz3334,garciavescovi@ibr-conicet.gov.ar,The inability of the mutant phoP strain to disseminate systemically remained unchanged by CLA treatment.,M A Carabajal 2020,2020,1 gene,Carabajal-2020-PhoQ is an unsaturated fatty ac,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16389,PHI:10415,UniProt,A0A411HE34,GenBank,AKC05671,,,3HP,PirA,,,,PirB,UniProt: A0A411J1B8; GenBank: AKC05670,,670,Vibrio parahaemolyticus,,M0904,acute hepatopancreatic necrosis disease,rodents,10114,Rattus (related: rat),Wistar,,,erythrocyte,toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32138213,PubMed,10.3390/pathogens9030182,Pathogens. 2020 Mar 3;9(3):182. doi: 10.3390/pathogens9030182,ssoto@ciad.mx,The rPirAvp showed no hemagglutinating capacity towards the animal red cells tested.,M Victorio-De Los Santos 2020,2020,2 genes,Victorio-De Los-2020-The B Subunit of PirAB(vp,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16390,PHI:10415,UniProt,A0A411HE34,GenBank,AKC05671,,,3HP,PirA,,,,PirB,UniProt: A0A411J1B8; GenBank: AKC05670,,670,Vibrio parahaemolyticus,,M0904,acute hepatopancreatic necrosis disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,erythrocyte,toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32138213,PubMed,10.3390/pathogens9030182,Pathogens. 2020 Mar 3;9(3):182. doi: 10.3390/pathogens9030182,ssoto@ciad.mx,The rPirAvp showed no hemagglutinating capacity towards the animal red cells tested.,M Victorio-De Los Santos 2020,2020,2 genes,Victorio-De Los-2020-The B Subunit of PirAB(vp,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16391,PHI:10415,UniProt,A0A411HE34,GenBank,AKC05671,,,3HP,PirA,,,,PirB,UniProt: A0A411J1B8; GenBank: AKC05670,,670,Vibrio parahaemolyticus,,M0904,acute hepatopancreatic necrosis disease,primates,9606,Homo sapiens (related: human),,,,erythrocyte,toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32138213,PubMed,10.3390/pathogens9030182,Pathogens. 2020 Mar 3;9(3):182. doi: 10.3390/pathogens9030182,ssoto@ciad.mx,The rPirAvp showed no hemagglutinating capacity towards the animal red cells tested.,M Victorio-De Los Santos 2020,2020,2 genes,Victorio-De Los-2020-The B Subunit of PirAB(vp,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16392,PHI:10415,UniProt,A0A411HE34,GenBank,AKC05671,,,3HP,PirA,,,,PirB,UniProt: A0A411J1B8; GenBank: AKC05670,,670,Vibrio parahaemolyticus,,M0904,acute hepatopancreatic necrosis disease,rodents,9986,Oryctolagus cuniculus (related: rabbit),,,,erythrocyte,toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32138213,PubMed,10.3390/pathogens9030182,Pathogens. 2020 Mar 3;9(3):182. doi: 10.3390/pathogens9030182,ssoto@ciad.mx,The rPirAvp showed no hemagglutinating capacity towards the animal red cells tested.,M Victorio-De Los Santos 2020,2020,2 genes,Victorio-De Los-2020-The B Subunit of PirAB(vp,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16393,PHI:10415,UniProt,A0A411HE34,GenBank,AKC05671,,,3HP,PirA,,,,PirB,UniProt: A0A411J1B8; GenBank: AKC05670,,670,Vibrio parahaemolyticus,,M0904,acute hepatopancreatic necrosis disease,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32138213,PubMed,10.3390/pathogens9030182,Pathogens. 2020 Mar 3;9(3):182. doi: 10.3390/pathogens9030182,ssoto@ciad.mx,The rPirAvp showed no hemagglutinating capacity towards the animal red cells tested.,M Victorio-De Los Santos 2020,2020,2 genes,Victorio-De Los-2020-The B Subunit of PirAB(vp,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16394,PHI:10416,UniProt,A0A411J1B8,GenBank,AKC05670,,,3HP,PirB,,,,PirA,UniProt: A0A411HE34; GenBank: AKC05671,,670,Vibrio parahaemolyticus,,M0904,acute hepatopancreatic necrosis disease,rodents,10114,Rattus (related: rat),Wistar,,,erythrocyte,toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32138213,PubMed,10.3390/pathogens9030182,Pathogens. 2020 Mar 3;9(3):182. doi: 10.3390/pathogens9030182,ssoto@ciad.mx,The PirABvp complex and the rPirBvp showed hemagglutinating activity toward rat erythrocytes.,M Victorio-De Los Santos 2020,2020,2 genes,Victorio-De Los-2020-The B Subunit of PirAB(vp,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16395,PHI:10416,UniProt,A0A411J1B8,GenBank,AKC05670,,,3HP,PirB,,,,PirA,UniProt: A0A411HE34; GenBank: AKC05671,,670,Vibrio parahaemolyticus,,M0904,acute hepatopancreatic necrosis disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,erythrocyte,toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32138213,PubMed,10.3390/pathogens9030182,Pathogens. 2020 Mar 3;9(3):182. doi: 10.3390/pathogens9030182,ssoto@ciad.mx,The PirABvp complex and the rPirBvp showed hemagglutinating activity toward rat erythrocytes.,M Victorio-De Los Santos 2020,2020,2 genes,Victorio-De Los-2020-The B Subunit of PirAB(vp,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16396,PHI:10416,UniProt,A0A411J1B8,GenBank,AKC05670,,,3HP,PirB,,,,PirA,UniProt: A0A411HE34; GenBank: AKC05671,,670,Vibrio parahaemolyticus,,M0904,acute hepatopancreatic necrosis disease,rodents,9986,Oryctolagus cuniculus (related: rabbit),,,,erythrocyte,toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32138213,PubMed,10.3390/pathogens9030182,Pathogens. 2020 Mar 3;9(3):182. doi: 10.3390/pathogens9030182,ssoto@ciad.mx,The PirABvp complex and the rPirBvp showed hemagglutinating activity toward rat erythrocytes.,M Victorio-De Los Santos 2020,2020,2 genes,Victorio-De Los-2020-The B Subunit of PirAB(vp,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16397,PHI:10416,UniProt,A0A411J1B8,GenBank,AKC05670,,,3HP,PirB,,,,PirA,UniProt: A0A411HE34; GenBank: AKC05671,,670,Vibrio parahaemolyticus,,M0904,acute hepatopancreatic necrosis disease,primates,9606,Homo sapiens (related: human),,,,erythrocyte,toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32138213,PubMed,10.3390/pathogens9030182,Pathogens. 2020 Mar 3;9(3):182. doi: 10.3390/pathogens9030182,ssoto@ciad.mx,The PirABvp complex and the rPirBvp showed hemagglutinating activity toward rat erythrocytes.,M Victorio-De Los Santos 2020,2020,2 genes,Victorio-De Los-2020-The B Subunit of PirAB(vp,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16398,PHI:10416,UniProt,A0A411J1B8,GenBank,AKC05670,,,3HP,PirB,,,,PirA,UniProt: A0A411HE34; GenBank: AKC05671,,670,Vibrio parahaemolyticus,,M0904,acute hepatopancreatic necrosis disease,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32138213,PubMed,10.3390/pathogens9030182,Pathogens. 2020 Mar 3;9(3):182. doi: 10.3390/pathogens9030182,ssoto@ciad.mx,The PirABvp complex and the rPirBvp showed hemagglutinating activity toward rat erythrocytes.,M Victorio-De Los Santos 2020,2020,2 genes,Victorio-De Los-2020-The B Subunit of PirAB(vp,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16399,PHI:10417,UniProt,Q7A656,GenBank,BAB42225,,,N315,IsdB,,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; blood infection; pneumonia,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,iron-regulated surface determinant protein B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32499371,PubMed,10.1074/jbc.RA120.013510,J Biol Chem. 2020 Jun 4:jbc.RA120.013510. doi: 10.1074/jbc.RA120.013510. Online ahead of print,pspeziale@unipv.it,S. aureus used Vn as a molecular bridge between surface-expressed IsdB and the alphavbeta3 integrin for promoting efficient adhesion and gaining entry of bacteria into HeLa or HUVEC cells.,G Pietrocola 2020,2020,1 gene,Pietrocola-2020-The iron-regulated surface det,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16400,PHI:10417,UniProt,Q7A656,GenBank,BAB42225,,,N315,IsdB,,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; blood infection; pneumonia,primates,9606,Homo sapiens (related: human),HUVEC-C cell line,,,umbilical vein endothelial cell,iron-regulated surface determinant protein B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32499371,PubMed,10.1074/jbc.RA120.013510,J Biol Chem. 2020 Jun 4:jbc.RA120.013510. doi: 10.1074/jbc.RA120.013510. Online ahead of print,pspeziale@unipv.it,S. aureus used Vn as a molecular bridge between surface-expressed IsdB and the alphavbeta3 integrin for promoting efficient adhesion and gaining entry of bacteria into HeLa or HUVEC cells.,G Pietrocola 2020,2020,1 gene,Pietrocola-2020-The iron-regulated surface det,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16401,PHI:10418,UniProt,A0A177DLA2,GenBank,OAG19619,,,SRC1lrK2f,AaBre1,,,,,,,5599,Alternaria alternata,,,infection,eudicots,41568,Chrysanthemum x morifolium (related: mum),,,,leaf,ubiquitin E3 ligase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32098172,PubMed,10.3390/genes11020229,Genes (Basel). 2020 Feb 21;11(2):229. doi: 10.3390/genes11020229,chenfd@njau.edu.cn,"AaBRE1 product, through its effect on histone 2B monoubiquitination and histone 3 lysine 4 trimethylation, made an important contribution to the fungus's hyphal growth, conidial formation and pathogenicity.",Y Liu 2020,2020,1 gene,Liu-2020-Ubiquitin E3 Ligase AaBre1 Responsibl,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16402,PHI:10419,UniProt,Q8Y8E0,GenBank,CAC99042,,,EGD-e,YjbH (lmo0964),,,,spxa1,UniProt: A0A112VBE9; GenBank: APA83455,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),L2 cell line,,,fibroblast cell line,protease adaptor,,,,reduced virulence,,,,,,,,,,no,ethanol; diamide; sodium nitroprusside; hydrogen peroxide,ethanol: CHEBI:16236; diamide: CHEBI:48958; sodium nitroprusside: CHEBI:29321; hydrogen peroxide: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,32253340,PubMed,10.1128/JB.00099-20,J Bacteriol. 2020 May 27;202(12):e00099-20. doi: 10.1128/JB.00099-20. Print 2020 May 27,reniere@uw.edu,"YjbH thioredoxin domain active motif was essential for L. monocytogenes sensitivity to nitrosative stress, cell-to-cell spread in a tissue culture model of infection",B R Ruhland 2020,2020,1 gene,Ruhland-2020-YjbH Requires Its Thioredoxin Act,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16403,PHI:10420,UniProt,A0A1E7X3M1,GenBank,EYB25165,,,CS3005,FgNahG (FG05_08116),,,,,,,5518,Fusarium graminearum,,DAOM 180378,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,salicylate hydroxylase,,,,reduced virulence,,,,,,,,reduced,,no,salicylic acid,salicylic acid: CHEBI:16914,,,,,gene deletion: full; gene complementation,,,YVS,30678154,PubMed,10.3390/toxins11020059,Toxins (Basel). 2019 Jan 22;11(2):59. doi: 10.3390/toxins11020059,ymwei@sicau.edu.cn,"Disrupting the FgNahG gene led to enhanced sensitivity to SA, increased accumulation of SA in wheat spikes during the early infection stage and inhibited development of head blight symptoms.",P F Qi 2019,2019,1 gene,Qi-2019-Functional Analysis of FgNahG Clarifie,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16404,PHI:10420,UniProt,A0A1E7X3M1,GenBank,EYB25165,,,CS3005,FgNahG (FG05_08116),,,,,,,5518,Fusarium graminearum,,DAOM 180378,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,salicylate hydroxylase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,salicylic acid,salicylic acid: CHEBI:16914,,,,,other evidence: transgenic plants,,,YVS,30678154,PubMed,10.3390/toxins11020059,Toxins (Basel). 2019 Jan 22;11(2):59. doi: 10.3390/toxins11020059,ymwei@sicau.edu.cn,"Disrupting the FgNahG gene led to enhanced sensitivity to SA, increased accumulation of SA in wheat spikes during the early infection stage and inhibited development of head blight symptoms.",P F Qi 2019,2019,1 gene,Qi-2019-Functional Analysis of FgNahG Clarifie,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16405,PHI:10421,UniProt,A0A0H2X6S6,GenBank,AAY48253,,,8004,PilG (XC_1183),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),,,,leaf,single domain response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32070276,PubMed,10.1186/s12866-020-1712-3,BMC Microbiol. 2020 Feb 18;20(1):37. doi: 10.1186/s12866-020-1712-3,lugt@gxu.edu.cn,PilG and PilH contributed to the regulation of chemotaxis and virulence in Xcc.,Y H Qi 2020,2020,2 genes,Qi-2020-PilG and PilH antagonistically control,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16406,PHI:10422,UniProt,A0A0H2X4W0,GenBank,AAY48254,,,8004,PilH (XC_1184),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),,,,leaf,single domain response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32070276,PubMed,10.1186/s12866-020-1712-3,BMC Microbiol. 2020 Feb 18;20(1):37. doi: 10.1186/s12866-020-1712-3,lugt@gxu.edu.cn,PilG and PilH contributed to the regulation of chemotaxis and virulence in Xcc.,Y H Qi 2020,2020,2 genes,Qi-2020-PilG and PilH antagonistically control,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16407,PHI:10423,UniProt,A0A0A1V4H7,GenBank,EXV05084,,,ARSEF 2575,kmt2,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,infection,mosquitos,30069,Anopheles stephensi (related: Asian malaria mosquito),Dutch strain,,,cuticle,histone lysine methyltransferase,,,,reduced virulence,,yes,yes,,,reduced,,reduced,wild type,no,,,,,,,gene deletion full; gene complementation,,,YVS,32232158,PubMed,10.1126/sciadv.aaz1659,Sci Adv. 2020 Mar 25;6(13):eaaz1659. doi: 10.1126/sciadv.aaz1659. eCollection 2020 Mar,weigang@picb.ac.cn,MrKMT2 regulated infection-related morphogenesis and fungal pathogenicity via MrCre1.,Y Lai 2020,2020,2 genes,Lai-2020-Coordinated regulation of infection-r,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16408,PHI:10424,UniProt,A0A0A1UVV3,GenBank,EXV01725,,,ARSEF 2575,cre1,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,infection,mosquitos,30069,Anopheles stephensi (related: Asian malaria mosquito),Dutch strain,,,cuticle,zinc-finger double-domain-containing transcription factor,,,,reduced virulence,,yes,yes,,,reduced,,reduced,wild type,no,,,,,,,gene deletion full; gene complementation,,,YVS,32232158,PubMed,10.1126/sciadv.aaz1659,Sci Adv. 2020 Mar 25;6(13):eaaz1659. doi: 10.1126/sciadv.aaz1659. eCollection 2020 Mar,weigang@picb.ac.cn,MrKMT2 regulated infection-related morphogenesis and fungal pathogenicity via MrCre1.,Y Lai 2020,2020,2 genes,Lai-2020-Coordinated regulation of infection-r,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16409,PHI:10424,UniProt,A0A0A1UVV3,GenBank,EXV01725,,,ARSEF 2575,cre1,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,infection,mosquitos,30069,Anopheles stephensi (related: Asian malaria mosquito),Dutch strain,,,cuticle,zinc-finger double-domain-containing transcription factor,,,,unaffected pathogenicity,,no,no,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32232158,PubMed,10.1126/sciadv.aaz1659,Sci Adv. 2020 Mar 25;6(13):eaaz1659. doi: 10.1126/sciadv.aaz1659. eCollection 2020 Mar,weigang@picb.ac.cn,MrKMT2 regulated infection-related morphogenesis and fungal pathogenicity via MrCre1.,Y Lai 2020,2020,2 genes,Lai-2020-Coordinated regulation of infection-r,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16410,PHI:10425,UniProt,G4NJI5,GenBank,EHA46401,,,70-15,PoMet3 (MGG_15027),chromosome 7,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast,monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,sulfate adenylyltransferase,,,,reduced virulence,,no,yes,yes,,wild type,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32125494,PubMed,10.1007/s00294-020-01055-1,Curr Genet. 2020 Mar 3,xhliu@zju.edu.cn,The defects of the null mutants could be restored by supplementing with exogenous cysteine or methionine.,Y Li 2020,2020,2 genes,Li-2020-PoMet3 and PoMet14 associated with sul,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16411,PHI:10426,UniProt,G4N7W0,GenBank,EHA50914,,,70-15,PoMet14 (MGG_06348),chromosome 4,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast,monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,adenylyl-sulfate kinase,,,,reduced virulence,,no,yes,yes,,wild type,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32125494,PubMed,10.1007/s00294-020-01055-1,Curr Genet. 2020 Mar 3,xhliu@zju.edu.cn,The defects of the null mutants could be restored by supplementing with exogenous cysteine or methionine.,Y Li 2020,2020,2 genes,Li-2020-PoMet3 and PoMet14 associated with sul,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16412,PHI:10425,UniProt,G4NJI5,GenBank,EHA46401,,,70-15,PoMet3 (MGG_15027),chromosome 7,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast,monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,sulfate adenylyltransferase,,,,reduced virulence,,no,yes,yes,,wild type,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32125494,PubMed,10.1007/s00294-020-01055-1,Curr Genet. 2020 Mar 3,xhliu@zju.edu.cn,The defects of the null mutants could be restored by supplementing with exogenous cysteine or methionine.,Y Li 2020,2020,2 genes,Li-2020-PoMet3 and PoMet14 associated with sul,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16413,PHI:10426,UniProt,G4N7W0,GenBank,EHA50914,,,70-15,PoMet14 (MGG_06348),chromosome 4,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast,monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,adenylyl-sulfate kinase,,,,reduced virulence,,no,yes,yes,,wild type,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32125494,PubMed,10.1007/s00294-020-01055-1,Curr Genet. 2020 Mar 3,xhliu@zju.edu.cn,The defects of the null mutants could be restored by supplementing with exogenous cysteine or methionine.,Y Li 2020,2020,2 genes,Li-2020-PoMet3 and PoMet14 associated with sul,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16414,PHI:10427,UniProt,Q9I5P9,GenBank,AE004503_2,,,PAO1,Vrei,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,bony fishes,7955,Danio rerio (related: zebrafish),Casper,,,embryo,ECF sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32081993,PubMed,10.1038/s41598-020-60197-x,Sci Rep. 2020 Feb 21;10(1):3139. doi: 10.1038/s41598-020-60197-x,llamas@eez.csic.es,"The vreI-vreR genes are expressed under inorganic phosphate (pi) starvation, a physiological condition often encountered in the host that increased P. aeruginosa pathogenicity.",J R Otero-Asman 2020,2020,2 genes,Otero-Asman-2020-The extracytoplasmic function,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16415,PHI:10428,UniProt,G3XCU5,GenBank,AE004503_3,,,PAO1,vreR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,bony fishes,7955,Danio rerio (related: zebrafish),Casper,,,embryo,sigma factor regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32081993,PubMed,10.1038/s41598-020-60197-x,Sci Rep. 2020 Feb 21;10(1):3139. doi: 10.1038/s41598-020-60197-x,llamas@eez.csic.es,"The vreI-vreR genes are expressed under inorganic phosphate (pi) starvation, a physiological condition often encountered in the host that increased P. aeruginosa pathogenicity.",J R Otero-Asman 2020,2020,2 genes,Otero-Asman-2020-The extracytoplasmic function,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16416,PHI:10427,UniProt,Q9I5P9,GenBank,AE004503_2,,,PAO1,Vrei,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,ECF sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32081993,PubMed,10.1038/s41598-020-60197-x,Sci Rep. 2020 Feb 21;10(1):3139. doi: 10.1038/s41598-020-60197-x,llamas@eez.csic.es,"The vreI-vreR genes are expressed under inorganic phosphate (pi) starvation, a physiological condition often encountered in the host that increased P. aeruginosa pathogenicity.",J R Otero-Asman 2020,2020,2 genes,Otero-Asman-2020-The extracytoplasmic function,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16417,PHI:10428,UniProt,G3XCU5,GenBank,AE004503_3,,,PAO1,vreR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,sigma factor regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32081993,PubMed,10.1038/s41598-020-60197-x,Sci Rep. 2020 Feb 21;10(1):3139. doi: 10.1038/s41598-020-60197-x,llamas@eez.csic.es,"The vreI-vreR genes are expressed under inorganic phosphate (pi) starvation, a physiological condition often encountered in the host that increased P. aeruginosa pathogenicity.",J R Otero-Asman 2020,2020,2 genes,Otero-Asman-2020-The extracytoplasmic function,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16418,PHI:10429,UniProt,Q8VLH6,GenBank,AF453441_49,,,83/39,NleB,,,,,,,562,Escherichia coli,574521,E2348/69,enteric disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32432056,PubMed,10.3389/fcimb.2020.00197,Front Cell Infect Microbiol. 2020 May 5;10:197. doi: 10.3389/fcimb.2020.00197. eCollection 2020,lishan@mail.hzau.edu.cn,"Mutation of the auto-modification sites of NleB, SseK1, and SseK3 abolished or attenuated the capability of enzyme activity toward their death domain targets during infection.",J Xue 2020,2020,3 genes,Xue-2020-Auto Arginine-GlcNAcylation Is Crucia,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16419,PHI:10429,UniProt,Q8VLH6,GenBank,AF453441_49,,,83/39,NleB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32432056,PubMed,10.3389/fcimb.2020.00197,Front Cell Infect Microbiol. 2020 May 5;10:197. doi: 10.3389/fcimb.2020.00197. eCollection 2020,lishan@mail.hzau.edu.cn,"Mutation of the auto-modification sites of NleB, SseK1, and SseK3 abolished or attenuated the capability of enzyme activity toward their death domain targets during infection.",J Xue 2020,2020,3 genes,Xue-2020-Auto Arginine-GlcNAcylation Is Crucia,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16420,PHI:10430,UniProt,A0A0H3NK84,GenBank,CBW20184,,,SL1344,SseK1,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32432056,PubMed,10.3389/fcimb.2020.00197,Front Cell Infect Microbiol. 2020 May 5;10:197. doi: 10.3389/fcimb.2020.00197. eCollection 2020,lishan@mail.hzau.edu.cn,"Mutation of the auto-modification sites of NleB, SseK1, and SseK3 abolished or attenuated the capability of enzyme activity toward their death domain targets during infection.",J Xue 2020,2020,3 genes,Xue-2020-Auto Arginine-GlcNAcylation Is Crucia,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16421,PHI:10430,UniProt,A0A0H3NK84,GenBank,CBW20184,,,SL1344,SseK1,,,,,,,562,Escherichia coli,574521,E2348/69,enteric disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32432056,PubMed,10.3389/fcimb.2020.00197,Front Cell Infect Microbiol. 2020 May 5;10:197. doi: 10.3389/fcimb.2020.00197. eCollection 2020,lishan@mail.hzau.edu.cn,"Mutation of the auto-modification sites of NleB, SseK1, and SseK3 abolished or attenuated the capability of enzyme activity toward their death domain targets during infection.",J Xue 2020,2020,3 genes,Xue-2020-Auto Arginine-GlcNAcylation Is Crucia,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16422,PHI:10431,UniProt,A0A0H3NMP8,GenBank,CBW18025,,,SL1344,SseK3,,,,,,,562,Escherichia coli,574521,E2348/69,enteric disease,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32432056,PubMed,10.3389/fcimb.2020.00197,Front Cell Infect Microbiol. 2020 May 5;10:197. doi: 10.3389/fcimb.2020.00197. eCollection 2020,lishan@mail.hzau.edu.cn,"Mutation of the auto-modification sites of NleB, SseK1, and SseK3 abolished or attenuated the capability of enzyme activity toward their death domain targets during infection.",J Xue 2020,2020,3 genes,Xue-2020-Auto Arginine-GlcNAcylation Is Crucia,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16423,PHI:10431,UniProt,A0A0H3NMP8,GenBank,CBW18025,,,SL1344,SseK3,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32432056,PubMed,10.3389/fcimb.2020.00197,Front Cell Infect Microbiol. 2020 May 5;10:197. doi: 10.3389/fcimb.2020.00197. eCollection 2020,lishan@mail.hzau.edu.cn,"Mutation of the auto-modification sites of NleB, SseK1, and SseK3 abolished or attenuated the capability of enzyme activity toward their death domain targets during infection.",J Xue 2020,2020,3 genes,Xue-2020-Auto Arginine-GlcNAcylation Is Crucia,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16424,PHI:10432,UniProt,A0A384K0L8,GenBank,ATZ56370,,,B05.10,bcCBH (Bcin13g02100),chromosome BCIN13,,,,,,40559,Botrytis cinerea,332648,B05.10,infection,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf; fruit,cellobiohydrolase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32098836,PubMed,10.1128/mSystems.00732-19,mSystems. 2020 Feb 25;5(1):e00732-19. doi: 10.1128/mSystems.00732-19,tsp@ibcas.ac.cn,BcactA played a crucial role in regulating the secretion of extracellular virulence factors.,H Li 2020,2020,3 genes,Li-2020-Actin Is Required for Cellular Develop,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16425,PHI:10433,UniProt,A0A384JRK6,GenBank,ATZ53132,,,B05.10,BcEG (Bcin09g00200),chromosome BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,infection,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf; fruit,beta-endoglucanase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32098836,PubMed,10.1128/mSystems.00732-19,mSystems. 2020 Feb 25;5(1):e00732-19. doi: 10.1128/mSystems.00732-19,tsp@ibcas.ac.cn,BcactA played a crucial role in regulating the secretion of extracellular virulence factors.,H Li 2020,2020,3 genes,Li-2020-Actin Is Required for Cellular Develop,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16426,PHI:10434,UniProt,A0A384K6F2,GenBank,ATZ58410,,,B05.10,BcactA (Bcin16g02020),chromosome BCIN16,,,,,,40559,Botrytis cinerea,332648,B05.10,infection,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf; fruit,conserved actin protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32098836,PubMed,10.1128/mSystems.00732-19,mSystems. 2020 Feb 25;5(1):e00732-19. doi: 10.1128/mSystems.00732-19,tsp@ibcas.ac.cn,BcactA played a crucial role in regulating the secretion of extracellular virulence factors.,H Li 2020,2020,3 genes,Li-2020-Actin Is Required for Cellular Develop,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16427,PHI:10432,UniProt,A0A384K0L8,GenBank,ATZ56370,,,B05.10,bcCBH (Bcin13g02100),chromosome BCIN13,,,,,,40559,Botrytis cinerea,332648,B05.10,infection,eudicots,3750,Malus domestica (related: apple),,,,fruit,cellobiohydrolase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32098836,PubMed,10.1128/mSystems.00732-19,mSystems. 2020 Feb 25;5(1):e00732-19. doi: 10.1128/mSystems.00732-19,tsp@ibcas.ac.cn,BcactA played a crucial role in regulating the secretion of extracellular virulence factors.,H Li 2020,2020,3 genes,Li-2020-Actin Is Required for Cellular Develop,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16428,PHI:10433,UniProt,A0A384JRK6,GenBank,ATZ53132,,,B05.10,BcEG (Bcin09g00200),chromosome BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,infection,eudicots,3750,Malus domestica (related: apple),,,,fruit,beta-endoglucanase,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32098836,PubMed,10.1128/mSystems.00732-19,mSystems. 2020 Feb 25;5(1):e00732-19. doi: 10.1128/mSystems.00732-19,tsp@ibcas.ac.cn,BcactA played a crucial role in regulating the secretion of extracellular virulence factors.,H Li 2020,2020,3 genes,Li-2020-Actin Is Required for Cellular Develop,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16429,PHI:10434,UniProt,A0A384K6F2,GenBank,ATZ58410,,,B05.10,BcactA (Bcin16g02020),chromosome BCIN16,,,,,,40559,Botrytis cinerea,332648,B05.10,infection,eudicots,3750,Malus domestica (related: apple),,,,fruit,conserved actin protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32098836,PubMed,10.1128/mSystems.00732-19,mSystems. 2020 Feb 25;5(1):e00732-19. doi: 10.1128/mSystems.00732-19,tsp@ibcas.ac.cn,BcactA played a crucial role in regulating the secretion of extracellular virulence factors.,H Li 2020,2020,3 genes,Li-2020-Actin Is Required for Cellular Develop,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16430,PHI:10435,UniProt,J9VXM5,GenBank,AFR99008,,,H99,chs3,chromosome 14,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,chitin synthase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32071275,PubMed,10.1128/mBio.03373-19,mBio. 2020 Feb 18;11(1):e03373-19,pengfeiqi@sicau.edu.cn,Rapid rate of mortality observed in mice inoculated with chs3Δ is neutrophil dependent.,C R Hole 2020,2020,4 genes,Hole-2020-Cryptococcus neoformans Chitin Synth,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16431,PHI:10435,UniProt,J9VXM5,GenBank,AFR99008,,,H99,chs3,chromosome 14,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,chitin synthase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32071275,PubMed,10.1128/mBio.03373-19,mBio. 2020 Feb 18;11(1):e03373-19,pengfeiqi@sicau.edu.cn,Rapid rate of mortality observed in mice inoculated with chs3Δ is neutrophil dependent.,C R Hole 2020,2020,4 genes,Hole-2020-Cryptococcus neoformans Chitin Synth,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16432,PHI:10435,UniProt,J9VXM5,GenBank,AFR99008,,,H99,chs3,chromosome 14,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,lung,chitin synthase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32071275,PubMed,10.1128/mBio.03373-19,mBio. 2020 Feb 18;11(1):e03373-19,pengfeiqi@sicau.edu.cn,Rapid rate of mortality observed in mice inoculated with chs3Δ is neutrophil dependent.,C R Hole 2020,2020,4 genes,Hole-2020-Cryptococcus neoformans Chitin Synth,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16433,PHI:10436,UniProt,Q5KFG8,GenBank,XP_571516,,,JEC21,cda1,chromosome 6,,,,,PHI:10437; PHI:10438,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,chitin deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32071275,PubMed,10.1128/mBio.03373-19,mBio. 2020 Feb 18;11(1):e03373-19,pengfeiqi@sicau.edu.cn,Rapid rate of mortality observed in mice inoculated with chs3Δ is neutrophil dependent.,C R Hole 2020,2020,4 genes,Hole-2020-Cryptococcus neoformans Chitin Synth,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16434,PHI:10437,UniProt,Q5KIC2,GenBank,AAW43254,,,JEC21,cda2,chromosome 4,,,,,PHI:10436; PHI:10438,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,chitin deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32071275,PubMed,10.1128/mBio.03373-19,mBio. 2020 Feb 18;11(1):e03373-19,pengfeiqi@sicau.edu.cn,Rapid rate of mortality observed in mice inoculated with chs3Δ is neutrophil dependent.,C R Hole 2020,2020,4 genes,Hole-2020-Cryptococcus neoformans Chitin Synth,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16435,PHI:10438,UniProt,P0CP76,GenBank,AAW42893,,,JEC21,cda3,chromosome 4,,,,,PHI:10436; PHI:10437,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,chitin deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32071275,PubMed,10.1128/mBio.03373-19,mBio. 2020 Feb 18;11(1):e03373-19,pengfeiqi@sicau.edu.cn,Rapid rate of mortality observed in mice inoculated with chs3Δ is neutrophil dependent.,C R Hole 2020,2020,4 genes,Hole-2020-Cryptococcus neoformans Chitin Synth,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16436,PHI:10439,UniProt,no data found,GenBank,,,,,nps2,,,,,,,5599,Alternaria alternata,,ATCC 66981,leaf blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,non-ribosomal peptide synthase,,,,reduced virulence,,,,,,increased,,aberrant,,no,,,,,,,gene deletion: full,,,YVS,32107432,PubMed,10.1038/s41598-020-60468-7,Sci Rep. 2020 Feb 27;10(1):3587. doi: 10.1038/s41598-020-60468-7,reinhard.fischer@KIT.edu,"Nps2, was required for the biosynthesis of intracellular ferricrocin, whereas Nps6 was needed for the formation of extracellular coprogen and coprogen B.",B Voß 2020,2020,2 genes,Voß-2020-Alternaria alternata uses two siderop,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16437,PHI:10440,UniProt,I6YWH2,GenBank,AFN69082,,,EV-MIL31,nps6,,,,,,,5599,Alternaria alternata,,ATCC 66981,leaf blight,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,non-ribosomal peptide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32107432,PubMed,10.1038/s41598-020-60468-7,Sci Rep. 2020 Feb 27;10(1):3587. doi: 10.1038/s41598-020-60468-7,reinhard.fischer@KIT.edu,"Nps2, was required for the biosynthesis of intracellular ferricrocin, whereas Nps6 was needed for the formation of extracellular coprogen and coprogen B.",B Voß 2020,2020,2 genes,Voß-2020-Alternaria alternata uses two siderop,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16438,PHI:10441,UniProt,G1X5C4,GenBank,EGX51669,,,ATCC 24927,Aoglo3 ((AOL_s00054g68)),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,cuticle,putative GTPase activating protein for ARF,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,reduced,no,Congo red; NaCl; sorbitol,Congo red: CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,YVS,32087364,PubMed,10.1016/j.fgb.2020.103352,Fungal Genet Biol. 2020 May;138:103352,jinkui960@ynu.edu.cn,Deletion of the Aoglo3 gene resulted in growth defects and an increase in hyphal septum. Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.,Y Ma 2020,2020,1 gene,Ma-2020-The Arf-GAP AoGlo3 regulates conidiati,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16439,PHI:10442,UniProt,I6YG87,GenBank,CCP46299,,,H37Rv,PE31 (Rv3477),,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,PE family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,diamide; H2O2,diamide: CHEBI:48958; H2O2: CHEBI:16240,,,,,heterologous expression,,,YVS,32117813,PubMed,10.3389/fcimb.2020.00040,Front Cell Infect Microbiol. 2020 Feb 7;10:40. doi: 10.3389/fcimb.2020.00040. eCollection 2020,georgex@swu.edu.cn,"PE31 expressing M. smegmatis showed more resistant to the low pH, diamide, H2O2 and surface stress.",M K Ali 2020,2020,1 gene,Ali-2020-Mycobacterium tuberculosis PE31 (Rv34,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16440,PHI:10443,UniProt,no data found,GenBank,AKJ35788,,,NJ-35,tle1,,,,,,,644,Aeromonas hydrophila,1416915,NJ-35,,bony fishes,7955,Danio rerio (related: zebrafish),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32448355,PubMed,10.1186/s13567-020-00794-w,Vet Res. 2020 May 24;51(1):71. doi: 10.1186/s13567-020-00794-w,liuyongjie@njau.edu.cn,"The deletion of tle1 resulted in signifcantly decreased bioflm formation, antibacterial competition ability and virulence in zebrafsh.",S Ma 2020,2020,1 gene,Ma-2020-Identification of a new effector-immun,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16441,PHI:10443,UniProt,no data found,GenBank,AKJ35788,,,NJ-35,tle1,,,,,,,644,Aeromonas hydrophila,1416915,NJ-35,,bony fishes,217509,Carassius carassius (related: crucian carp),,,,heart; hepatopancreas; spleen; kidney,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32448355,PubMed,10.1186/s13567-020-00794-w,Vet Res. 2020 May 24;51(1):71. doi: 10.1186/s13567-020-00794-w,liuyongjie@njau.edu.cn,"The deletion of tle1 resulted in signifcantly decreased bioflm formation, antibacterial competition ability and virulence in zebrafsh.",S Ma 2020,2020,1 gene,Ma-2020-Identification of a new effector-immun,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16442,PHI:10444,UniProt,Q8FDW4,GenBank,AF289092_1,,,CFT073,sat,,,,,,,562,Escherichia coli,,EAEC CV323/77,infection,rodents,10090,Mus musculus (related: house mouse),Y1 cell line,,,adrenocortical cell,secreted serine protease autotransporter toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,32084148,PubMed,10.1371/journal.pone.0228959,PLoS One. 2020 Feb 21;15(2):e0228959. doi: 10.1371/journal.pone.0228959. eCollection 2020,rita.ruiz@butantan.gov.br,Sat induced cytotoxic effect during EAEC infection in vitro.,P C G Vieira 2020,2020,1 gene,Vieira-2020-Secreted autotransporter toxin (Sa,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16443,PHI:10444,UniProt,Q8FDW4,GenBank,AF289092_1,,,CFT073,sat,,,,,,,562,Escherichia coli,,EAEC CV323/77,infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colorectal adenocarcinoma cell,secreted serine protease autotransporter toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,32084148,PubMed,10.1371/journal.pone.0228959,PLoS One. 2020 Feb 21;15(2):e0228959. doi: 10.1371/journal.pone.0228959. eCollection 2020,rita.ruiz@butantan.gov.br,Sat induced cytotoxic effect during EAEC infection in vitro.,P C G Vieira 2020,2020,1 gene,Vieira-2020-Secreted autotransporter toxin (Sa,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16444,PHI:10444,UniProt,Q8FDW4,GenBank,AF289092_1,,,CFT073,sat,,,,,,,562,Escherichia coli,,EAEC CV323/77,infection,primates,9606,Homo sapiens (related: human),LLC-PK1 cell line,,,kidney cell line,secreted serine protease autotransporter toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,32084148,PubMed,10.1371/journal.pone.0228959,PLoS One. 2020 Feb 21;15(2):e0228959. doi: 10.1371/journal.pone.0228959. eCollection 2020,rita.ruiz@butantan.gov.br,Sat induced cytotoxic effect during EAEC infection in vitro.,P C G Vieira 2020,2020,1 gene,Vieira-2020-Secreted autotransporter toxin (Sa,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16445,PHI:10444,UniProt,Q8FDW4,GenBank,AF289092_1,,,CFT073,sat,,,,,,,562,Escherichia coli,,EAEC CV323/77,infection,primates,9606,Homo sapiens (related: human),HUVEC-C cell line,,,umbilical vein endothelial cell,secreted serine protease autotransporter toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression of recombinant protein,,,YVS,32084148,PubMed,10.1371/journal.pone.0228959,PLoS One. 2020 Feb 21;15(2):e0228959. doi: 10.1371/journal.pone.0228959. eCollection 2020,rita.ruiz@butantan.gov.br,Sat induced cytotoxic effect during EAEC infection in vitro.,P C G Vieira 2020,2020,1 gene,Vieira-2020-Secreted autotransporter toxin (Sa,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16446,PHI:10445,UniProt,A0A2L1CGE9,GenBank,AVC43502,,,TCH2015,ClpB,,,,dnaK,UniProt: A0A1I9YAX2; GenBank: CWW61749,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,chaperone protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32275693,PubMed,10.1371/journal.ppat.1008466,PLoS Pathog. 2020 Apr 10;16(4):e1008466. doi: 10.1371/journal.ppat.1008466. eCollection 2020 Apr,anders.sjostedt@umu.se,"The N-terminus of clpB was dispensable for heat shock, but required for T6S, intracellular replication in macrophages, and virulence.",A Alam 2020,2020,1 gene,Alam-2020-Dissociation between the critical ro,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16447,PHI:10445,UniProt,A0A2L1CGE9,GenBank,AVC43502,,,TCH2015,ClpB,,Y503Acis,,dnaK,UniProt: A0A1I9YAX2; GenBank: CWW61749,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,chaperone protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32275693,PubMed,10.1371/journal.ppat.1008466,PLoS Pathog. 2020 Apr 10;16(4):e1008466. doi: 10.1371/journal.ppat.1008466. eCollection 2020 Apr,anders.sjostedt@umu.se,"The N-terminus of clpB was dispensable for heat shock, but required for T6S, intracellular replication in macrophages, and virulence.",A Alam 2020,2020,1 gene,Alam-2020-Dissociation between the critical ro,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16448,PHI:10445,UniProt,A0A2L1CGE9,GenBank,AVC43502,,,TCH2015,ClpB,,"single Walker A motif double mutants of NBD-1 (K212A, designated WA1) and NBD-2 (K613A–WA2); Walker B motif double mutants of NBD-1 (E279A–WB1) and NBD-2 (E680A–WB2); Arginine finger double mutants of NBD-1 (R332A–Arg1) and NBD-2 (R757A–Arg2)",,dnaK,UniProt: A0A1I9YAX2; GenBank: CWW61749,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,chaperone protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32275693,PubMed,10.1371/journal.ppat.1008466,PLoS Pathog. 2020 Apr 10;16(4):e1008466. doi: 10.1371/journal.ppat.1008466. eCollection 2020 Apr,anders.sjostedt@umu.se,"The N-terminus of clpB was dispensable for heat shock, but required for T6S, intracellular replication in macrophages, and virulence.",A Alam 2020,2020,1 gene,Alam-2020-Dissociation between the critical ro,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16449,PHI:10445,UniProt,A0A2L1CGE9,GenBank,AVC43502,,,TCH2015,ClpB,,N-terminal truncated (ΔNClpB) variant of ClpB lacking 1-56 amino acids,,dnaK,UniProt: A0A1I9YAX2; GenBank: CWW61749,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,chaperone protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32275693,PubMed,10.1371/journal.ppat.1008466,PLoS Pathog. 2020 Apr 10;16(4):e1008466. doi: 10.1371/journal.ppat.1008466. eCollection 2020 Apr,anders.sjostedt@umu.se,"The N-terminus of clpB was dispensable for heat shock, but required for T6S, intracellular replication in macrophages, and virulence.",A Alam 2020,2020,1 gene,Alam-2020-Dissociation between the critical ro,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16450,PHI:10446,UniProt,A0A014QTQ8,GenBank,EXU96288,,,ARSEF 2575,M35-4,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,M35 family metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32079481,PubMed,10.1080/21505594.2020.1731126,Virulence. 2020 Dec;11(1):222-237,wangcs@sippe.ac.cn,MrM35-4 was required in M. robertsii to inhibit melanization activity and suppressing antifungal gene expression in insects.,A Huang 2020,2020,1 gene,Huang-2020-A M35 family metalloprotease is req,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16451,PHI:10447,UniProt,Q9I321,GenBank,AE004598_2,,,PAO1,exsD,,,,,,PHI:10448,287,Pseudomonas aeruginosa,208964,PAO1,infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ear,T3SS activator,,,alginate biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32416139,PubMed,10.1016/j.micpath.2020.104254,Microb Pathog. 2020 May 13;147:104254,kai.p.leung.civ@mail.mil,The re-epithelialization of infected-wound was signicantly delayed in double mutants.,S L R Karna 2020,2020,2 genes,Karna-2020-T3SS and alginate biosynthesis of P,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16452,PHI:10448,UniProt,P11759,GenBank,AE004774_6,,,PAO1,algD,,,,,,PHI:10447,287,Pseudomonas aeruginosa,208964,PAO1,infection,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ear,GDP-mannose 6-dehydrogenase,,,alginate biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32416139,PubMed,10.1016/j.micpath.2020.104254,Microb Pathog. 2020 May 13;147:104254,kai.p.leung.civ@mail.mil,The re-epithelialization of infected-wound was signicantly delayed in double mutants.,S L R Karna 2020,2020,2 genes,Karna-2020-T3SS and alginate biosynthesis of P,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16453,PHI:10447,UniProt,Q9I321,GenBank,AE004598_2,,,PAO1,exsD,,,,,,PHI:10448,287,Pseudomonas aeruginosa,208964,PAO1,infection,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,T3SS activator,,,alginate biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32416139,PubMed,10.1016/j.micpath.2020.104254,Microb Pathog. 2020 May 13;147:104254,kai.p.leung.civ@mail.mil,The double mutant showed greater susceptibility to macrophage phagocytosis in vitro than all other strains.,S L R Karna 2020,2020,2 genes,Karna-2020-T3SS and alginate biosynthesis of P,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16454,PHI:10448,UniProt,P11759,GenBank,AE004774_6,,,PAO1,algD,,,,,,PHI:10447,287,Pseudomonas aeruginosa,208964,PAO1,infection,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,GDP-mannose 6-dehydrogenase,,,alginate biosynthesis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32416139,PubMed,10.1016/j.micpath.2020.104254,Microb Pathog. 2020 May 13;147:104254,kai.p.leung.civ@mail.mil,The double mutant showed greater susceptibility to macrophage phagocytosis in vitro than all other strains.,S L R Karna 2020,2020,2 genes,Karna-2020-T3SS and alginate biosynthesis of P,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16455,PHI:10449,UniProt,A0A098DJU9,GenBank,CEF78732,,,PH-1,FCA7 (FGSG_12369),chromosome 2,,,,,,5518,Fusarium graminearum,449239,GZ3639,head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,bifunctional catalase-peroxidase,,,,reduced virulence,,,,,,wild type,wild type,,,no,H2O2; menadione; diamide,H2O2: CHEBI:16240; menadione: CHEBI:28869; diamide: CHEBI:48958,,,,,gene deletion: full,,,YVS,28387997,PubMed,10.1111/mpp.12557,Mol Plant Pathol. 2018 Mar;19(3):715-730. doi: 10.1111/mpp.12557. Epub 2017 May 2,lee2443@snu.ac.kr,Deletion mutants of FCA7 exhibited reduced virulence and increased trichothecene production compared with those of the wild-type strain.,Y Lee 2018,2018,7 genes,Lee-2018-Genome-wide functional characterizati,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16456,PHI:10450,UniProt,I1RGU6,GenBank,CEF77677,,,PH-1,FCA6 (FGSG_02974),chromosome 2,,,,,,5518,Fusarium graminearum,449239,GZ3639,head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,bifunctional catalase-peroxidase,,,,unaffected pathogenicity,,,,,,wild type,wild type,,,no,H2O2; menadione; diamide,H2O2: CHEBI:16240; menadione: CHEBI:28869; diamide: CHEBI:48958,,,,,gene deletion: full,,,YVS,28387997,PubMed,10.1111/mpp.12557,Mol Plant Pathol. 2018 Mar;19(3):715-730. doi: 10.1111/mpp.12557. Epub 2017 May 2,lee2443@snu.ac.kr,Deletion mutants of FCA7 exhibited reduced virulence and increased trichothecene production compared with those of the wild-type strain.,Y Lee 2018,2018,7 genes,Lee-2018-Genome-wide functional characterizati,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16457,PHI:10451,UniProt,Q4ING3,GenBank,ESU06535,,,PH-1,FPX1 (FGSG_01245),chromosome 1,,,,,,5518,Fusarium graminearum,449239,GZ3639,head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,cytochrome c peroxidase,,,,unaffected pathogenicity,,,,,,wild type,wild type,,,no,H2O2; menadione; diamide,H2O2: CHEBI:16240; menadione: CHEBI:28869; diamide: CHEBI:48958,,,,,gene deletion: full,,,YVS,28387997,PubMed,10.1111/mpp.12557,Mol Plant Pathol. 2018 Mar;19(3):715-730. doi: 10.1111/mpp.12557. Epub 2017 May 2,lee2443@snu.ac.kr,Deletion mutants of FCA7 exhibited reduced virulence and increased trichothecene production compared with those of the wild-type strain.,Y Lee 2018,2018,7 genes,Lee-2018-Genome-wide functional characterizati,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16458,PHI:10452,UniProt,A0A098DJ03,GenBank,CEF77926,,,PH-1,FPX15 (FGSG_03180),chromosome 2,,,,,,5518,Fusarium graminearum,449239,GZ3639,head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,peroxiredoxin,,,,unaffected pathogenicity,,,,,,wild type,wild type,,,no,H2O2; menadione; diamide,H2O2: CHEBI:16240; menadione: CHEBI:28869; diamide: CHEBI:48958,,,,,gene deletion: full,,,YVS,28387997,PubMed,10.1111/mpp.12557,Mol Plant Pathol. 2018 Mar;19(3):715-730. doi: 10.1111/mpp.12557. Epub 2017 May 2,lee2443@snu.ac.kr,Deletion mutants of FCA7 exhibited reduced virulence and increased trichothecene production compared with those of the wild-type strain.,Y Lee 2018,2018,7 genes,Lee-2018-Genome-wide functional characterizati,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16459,PHI:10453,UniProt,I1RB34,GenBank,CEF72736,,,PH-1,noxA (FGSG_00739),chromosome 1,,,,,,5518,Fusarium graminearum,449239,GZ3639,head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,NADPH oxidase,,,,reduced virulence,,,,,,wild type,reduced; aberrant,,,no,H2O2; menadione; diamide,H2O2: CHEBI:16240; menadione: CHEBI:28869; diamide: CHEBI:48958,,,,,gene deletion: full,,,YVS,28387997,PubMed,10.1111/mpp.12557,Mol Plant Pathol. 2018 Mar;19(3):715-730. doi: 10.1111/mpp.12557. Epub 2017 May 2,lee2443@snu.ac.kr,Deletion mutants of FCA7 exhibited reduced virulence and increased trichothecene production compared with those of the wild-type strain.,Y Lee 2018,2018,7 genes,Lee-2018-Genome-wide functional characterizati,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16460,PHI:10454,UniProt,A0A0E0SQ29,GenBank,CEF88542,,,PH-1,noxB (FGSG_10807),chromosome 3,,,,,,5518,Fusarium graminearum,449239,GZ3639,head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,NADPH oxidase,,,,unaffected pathogenicity,,,,,,wild type,wild type,,,no,H2O2; menadione; diamide,H2O2: CHEBI:16240; menadione: CHEBI:28869; diamide: CHEBI:48958,,,,,gene deletion: full,,,YVS,28387997,PubMed,10.1111/mpp.12557,Mol Plant Pathol. 2018 Mar;19(3):715-730. doi: 10.1111/mpp.12557. Epub 2017 May 2,lee2443@snu.ac.kr,Deletion mutants of FCA7 exhibited reduced virulence and increased trichothecene production compared with those of the wild-type strain.,Y Lee 2018,2018,7 genes,Lee-2018-Genome-wide functional characterizati,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16461,PHI:10455,UniProt,I1S333,GenBank,CEF87058,,,PH-1,noxC (FGSG_11195),chromosome 3,,,,,,5518,Fusarium graminearum,449239,GZ3639,head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,NADPH oxidase,,,,unaffected pathogenicity,,,,,,wild type,wild type,,,no,H2O2; menadione; diamide,H2O2: CHEBI:16240; menadione: CHEBI:28869; diamide: CHEBI:48958,,,,,gene deletion: full,,,YVS,28387997,PubMed,10.1111/mpp.12557,Mol Plant Pathol. 2018 Mar;19(3):715-730. doi: 10.1111/mpp.12557. Epub 2017 May 2,lee2443@snu.ac.kr,Deletion mutants of FCA7 exhibited reduced virulence and increased trichothecene production compared with those of the wild-type strain.,Y Lee 2018,2018,7 genes,Lee-2018-Genome-wide functional characterizati,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16462,PHI:10456,UniProt,no data found,GenBank,,,,,cnx1,,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,calnexin,,,,reduced virulence,,no,yes,yes,,reduced,,reduced,,no,tunicamycin,tunicamycin: CHEBI:29699,,,,,gene deletion: full; gene complementation,,,YVS,32092131,PubMed,10.1371/journal.ppat.1008355,PLoS Pathog. 2020 Feb 24;16(2):e1008355. doi: 10.1371/journal.ppat.1008355. eCollection 2020 Feb,wendeliu@126.com,"Gls1, Gls2, GTB1 and Cnx1, were important for mycelial growth, conidiation, and invasive hyphal growth in host cells.",X L Chen 2020,2020,4 genes,Chen-2020-Quantitative proteomics analysis rev,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16463,PHI:10457,UniProt,L7JF68,GenBank,ELQ66876,,,P131,Gls1,,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,"1,3-beta-glucan synthase component",,,,reduced virulence,,no,yes,yes,,reduced,,reduced,,no,tunicamycin,tunicamycin: CHEBI:29699,,,,,gene deletion: full; gene complementation,,,YVS,32092131,PubMed,10.1371/journal.ppat.1008355,PLoS Pathog. 2020 Feb 24;16(2):e1008355. doi: 10.1371/journal.ppat.1008355. eCollection 2020 Feb,wendeliu@126.com,"Gls1, Gls2, GTB1 and Cnx1, were important for mycelial growth, conidiation, and invasive hyphal growth in host cells.",X L Chen 2020,2020,4 genes,Chen-2020-Quantitative proteomics analysis rev,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16464,PHI:10458,UniProt,no data found,GenBank,,,,,Gls2,,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,"1,3-beta-glucan synthase component",,,,reduced virulence,,no,yes,yes,,reduced,,reduced,,no,tunicamycin,tunicamycin: CHEBI:29699,,,,,gene deletion: full; gene complementation,,,YVS,32092131,PubMed,10.1371/journal.ppat.1008355,PLoS Pathog. 2020 Feb 24;16(2):e1008355. doi: 10.1371/journal.ppat.1008355. eCollection 2020 Feb,wendeliu@126.com,"Gls1, Gls2, GTB1 and Cnx1, were important for mycelial growth, conidiation, and invasive hyphal growth in host cells.",X L Chen 2020,2020,4 genes,Chen-2020-Quantitative proteomics analysis rev,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16465,PHI:10459,UniProt,L7JCL9,GenBank,ELQ65951,,,P131,Gtb1,,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,glucosidase 2 subunit beta,,,,reduced virulence,,no,yes,yes,,reduced,,reduced,,no,tunicamycin,tunicamycin: CHEBI:29699,,,,,gene deletion: full; gene complementation,,,YVS,32092131,PubMed,10.1371/journal.ppat.1008355,PLoS Pathog. 2020 Feb 24;16(2):e1008355. doi: 10.1371/journal.ppat.1008355. eCollection 2020 Feb,wendeliu@126.com,"Gls1, Gls2, GTB1 and Cnx1, were important for mycelial growth, conidiation, and invasive hyphal growth in host cells.",X L Chen 2020,2020,4 genes,Chen-2020-Quantitative proteomics analysis rev,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16466,PHI:10457,UniProt,L7JF68,GenBank,ELQ66876,,,P131,Gls1,,Gls1 N497Q,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,"1,3-beta-glucan synthase component",,,,reduced virulence,,no,yes,yes,,reduced,,wild type,,no,tunicamycin,tunicamycin: CHEBI:29699,,,,,gene mutation; gene complementation,,,YVS,32092131,PubMed,10.1371/journal.ppat.1008355,PLoS Pathog. 2020 Feb 24;16(2):e1008355. doi: 10.1371/journal.ppat.1008355. eCollection 2020 Feb,wendeliu@126.com,"Gls1 N-glycosite N497 was important for invasive hyphal growth and partially required for conidiation, but didn't affect colony growth.",X L Chen 2020,2020,4 genes,Chen-2020-Quantitative proteomics analysis rev,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16467,PHI:10460,UniProt,O60026,GenBank,CAA76740,,,ATCC 46645,pksP,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32071276,PubMed,10.1128/mBio.03415-19,mBio. 2020 Feb 18;11(1):e03415-19. doi: 10.1128/mBio.03415-19,npkeller@wisc.edu,DHN-melanin role in virulence in three A. fumigatus isolates did not correlate with its role in UV-C protection.,A Blachowicz 2020,2020,4 genes,Blachowicz-2020-Contributions of Spore Seconda,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16468,PHI:10460,UniProt,O60026,GenBank,CAA76740,,,ATCC 46645,pksP,,,,,,,746128,Aspergillus fumigatus,,IF1SW-F4,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32071276,PubMed,10.1128/mBio.03415-19,mBio. 2020 Feb 18;11(1):e03415-19. doi: 10.1128/mBio.03415-19,npkeller@wisc.edu,DHN-melanin role in virulence in three A. fumigatus isolates did not correlate with its role in UV-C protection.,A Blachowicz 2020,2020,4 genes,Blachowicz-2020-Contributions of Spore Seconda,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16469,PHI:10460,UniProt,O60026,GenBank,CAA76740,,,ATCC 46645,pksP,,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32071276,PubMed,10.1128/mBio.03415-19,mBio. 2020 Feb 18;11(1):e03415-19. doi: 10.1128/mBio.03415-19,npkeller@wisc.edu,DHN-melanin role in virulence in three A. fumigatus isolates did not correlate with its role in UV-C protection.,A Blachowicz 2020,2020,4 genes,Blachowicz-2020-Contributions of Spore Seconda,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16470,PHI:10461,UniProt,Q4WLW5,GenBank,EAL89049,,,Af293,fmqA,chromosome 6,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,"nonribosomal peptide synthase, putative",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32071276,PubMed,10.1128/mBio.03415-19,mBio. 2020 Feb 18;11(1):e03415-19. doi: 10.1128/mBio.03415-19,npkeller@wisc.edu,DHN-melanin role in virulence in three A. fumigatus isolates did not correlate with its role in UV-C protection.,A Blachowicz 2020,2020,4 genes,Blachowicz-2020-Contributions of Spore Seconda,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16471,PHI:10462,UniProt,Q50EL0,GenBank,AAX08549,,,AF293/B5233,dmaW,,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,tryptophan dimethylallyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32071276,PubMed,10.1128/mBio.03415-19,mBio. 2020 Feb 18;11(1):e03415-19. doi: 10.1128/mBio.03415-19,npkeller@wisc.edu,DHN-melanin role in virulence in three A. fumigatus isolates did not correlate with its role in UV-C protection.,A Blachowicz 2020,2020,4 genes,Blachowicz-2020-Contributions of Spore Seconda,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16472,PHI:10463,UniProt,Q4WQZ5,GenBank,EAL89339,,,Af293,tpcC,chromosome 4,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,"polyketide synthase, putative",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32071276,PubMed,10.1128/mBio.03415-19,mBio. 2020 Feb 18;11(1):e03415-19. doi: 10.1128/mBio.03415-19,npkeller@wisc.edu,DHN-melanin role in virulence in three A. fumigatus isolates did not correlate with its role in UV-C protection.,A Blachowicz 2020,2020,4 genes,Blachowicz-2020-Contributions of Spore Seconda,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16473,PHI:10464,UniProt,D0P1A8,GenBank,EEY54134,,,T30-4,Avrblb2,,,,,,,4787,Phytophthora infestans,,F80029,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Bintje; cv. Bionika,,,leaf,effector protein,,,,effector (plant avirulence determinant),yes,,,,,,reduced,,,no,,,,,,,gene deletion: full,,,YVS,32153537,PubMed,10.3389/fmicb.2020.00252,Front Microbiol. 2020 Feb 21;11:252. doi: 10.3389/fmicb.2020.00252. eCollection 2020,georgios.tzelepis@slu.se,"Avrblb2 knock-down strains displayed a reduction in virulence and oospore formation, suggesting a role during the mating process.",G Tzelepis 2020,2020,1 gene,Tzelepis-2020-Dominance of Mating Type A1 and,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16474,PHI:10465,UniProt,D3YN29,GenBank,ADC80912,,,,mp1,,,,,,,173,Leptospira interrogans,57678,Lai,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,blood; lung; liver; kidney; urine,M16-type metallopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32274497,PubMed,10.1093/infdis/jiaa176,J Infect Dis. 2020 Apr 10:jiaa176. doi: 10.1093/infdis/jiaa176. Online ahead of print,med_bp@zju.edu.cn,"The transmigration of the ΔMP1/3 mutants, but not ΔMP2 mutant, through FHC, HUVEC, or HEK293 cell monolayers was significantly attenuated compared to transmigration of the wild-type.",Y M Ge 2020,2020,3 genes,Ge-2020-M16-type metallopeptidases are involve,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16475,PHI:10466,UniProt,no data found,GenBank,,,,,mp3,,,,,,,173,Leptospira interrogans,57678,Lai,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,blood; lung; liver; kidney; urine,M16-type metallopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32274497,PubMed,10.1093/infdis/jiaa176,J Infect Dis. 2020 Apr 10:jiaa176. doi: 10.1093/infdis/jiaa176. Online ahead of print,med_bp@zju.edu.cn,"The transmigration of the ΔMP1/3 mutants, but not ΔMP2 mutant, through FHC, HUVEC, or HEK293 cell monolayers was significantly attenuated compared to transmigration of the wild-type.",Y M Ge 2020,2020,3 genes,Ge-2020-M16-type metallopeptidases are involve,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16476,PHI:10467,UniProt,no data found,GenBank,,,,,mp2,,,,,,,173,Leptospira interrogans,57678,Lai,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,blood; lung; liver; kidney; urine,M16-type metallopeptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32274497,PubMed,10.1093/infdis/jiaa176,J Infect Dis. 2020 Apr 10:jiaa176. doi: 10.1093/infdis/jiaa176. Online ahead of print,med_bp@zju.edu.cn,"The transmigration of the ΔMP1/3 mutants, but not ΔMP2 mutant, through FHC, HUVEC, or HEK293 cell monolayers was significantly attenuated compared to transmigration of the wild-type.",Y M Ge 2020,2020,3 genes,Ge-2020-M16-type metallopeptidases are involve,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16477,PHI:10468,UniProt,F2SSE4,GenBank,EGD89154,,,CBS 118892,hacA (TERG_05396),,,,,,,5551,Trichophyton rubrum,,CBS 118892,skin infection; nail infection,primates,9606,Homo sapiens (related: human),,,,nail,bZip domain-containing protein,,,,reduced virulence,,,,,,,,,,no,DTT; ketoconazole; griseofulvin; terbinafine,DTT: CHEBI:42170; ketoconazole: CHEBI:48336; griseofulvin: CHEBI:27779; terbinafine: CHEBI:9448,,,,,gene deletion: full,,,YVS,32153523,PubMed,10.3389/fmicb.2020.00193,Front Microbiol. 2020 Feb 20;11:193. doi: 10.3389/fmicb.2020.00193. eCollection 2020,nmmrossi@usp.br,The ΔhacA mutant presented significant defects in important virulence traits like thermotolerance and growth on keratin substrates.,T A Bitencourt 2020,2020,1 gene,Bitencourt-2020-HacA Governs Virulence Traits,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16478,PHI:10468,UniProt,F2SSE4,GenBank,EGD89154,,,CBS 118892,hacA (TERG_05396),,,,,,,5551,Trichophyton rubrum,,CBS 118892,skin infection; nail infection,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,bZip domain-containing protein,,,,reduced virulence,,,,,,,,,,no,DTT; ketoconazole; griseofulvin; terbinafine,DTT: CHEBI:42170; ketoconazole: CHEBI:48336; griseofulvin: CHEBI:27779; terbinafine: CHEBI:9448,,,,,gene deletion: full,,,YVS,32153523,PubMed,10.3389/fmicb.2020.00193,Front Microbiol. 2020 Feb 20;11:193. doi: 10.3389/fmicb.2020.00193. eCollection 2020,nmmrossi@usp.br,The ΔhacA mutant presented significant defects in important virulence traits like thermotolerance and growth on keratin substrates.,T A Bitencourt 2020,2020,1 gene,Bitencourt-2020-HacA Governs Virulence Traits,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16479,PHI:10469,UniProt,A1JLB7,GenBank,CAL11489,,,8081,RcsB (YE1397),,,,,,,630,Yersinia enterocolitica,,,yersiniosis; acute gastroenteritis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,transcriptional regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32488337,PubMed,10.1007/s00294-020-01083-x,Curr Genet. 2020 Jun 3. doi: 10.1007/s00294-020-01083-x. Online ahead of print,chenjy@cau.edu.cn,"ΔRcsB mutant activated chemotactic behavior and flagella biosynthesis, and exhibited enhanced adhesion and invasion of Y. enterocolitica to Caco-2 cells.",J Meng 2020,2020,1 gene,Meng-2020-Transcriptomic analysis reveals the,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16480,PHI:10470,UniProt,Q2FUX7,GenBank,ABD31958,,,NCTC 8325,arcA,,,,,,,1280,Staphylococcus aureus,,USA300 2406,skin infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,arginine deiminase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32085445,PubMed,10.3390/microorganisms8020275,Microorganisms. 2020 Feb 18;8(2):275. doi: 10.3390/microorganisms8020275,kzhang@ucalgary.ca,"ACME did not contribute to bacterial virulence in cell invasion and cytotoxicity assays, invertebrate killing assays and a mouse skin infection model.",K Wu 2020,2020,2 genes,Wu-2020-Arginine Catabolic Mobile Element in E,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16481,PHI:10471,UniProt,no data found,GenBank,,,,,ACME,,,,,,,1280,Staphylococcus aureus,,USA300 2406,skin infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,arginine catabolic mobile element,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32085445,PubMed,10.3390/microorganisms8020275,Microorganisms. 2020 Feb 18;8(2):275. doi: 10.3390/microorganisms8020275,kzhang@ucalgary.ca,"ACME did not contribute to bacterial virulence in cell invasion and cytotoxicity assays, invertebrate killing assays and a mouse skin infection model.",K Wu 2020,2020,2 genes,Wu-2020-Arginine Catabolic Mobile Element in E,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16482,PHI:10471,UniProt,no data found,GenBank,,,,,ACME,,,,,,,1280,Staphylococcus aureus,,USA300 2406,skin infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,arginine catabolic mobile element,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32085445,PubMed,10.3390/microorganisms8020275,Microorganisms. 2020 Feb 18;8(2):275. doi: 10.3390/microorganisms8020275,kzhang@ucalgary.ca,"ACME did not contribute to bacterial virulence in cell invasion and cytotoxicity assays, invertebrate killing assays and a mouse skin infection model.",K Wu 2020,2020,2 genes,Wu-2020-Arginine Catabolic Mobile Element in E,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16483,PHI:10471,UniProt,no data found,GenBank,,,,,ACME,,,,,,,1280,Staphylococcus aureus,,USA300 2406,skin infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,arginine catabolic mobile element,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32085445,PubMed,10.3390/microorganisms8020275,Microorganisms. 2020 Feb 18;8(2):275. doi: 10.3390/microorganisms8020275,kzhang@ucalgary.ca,"ACME did not contribute to bacterial virulence in cell invasion and cytotoxicity assays, invertebrate killing assays and a mouse skin infection model.",K Wu 2020,2020,2 genes,Wu-2020-Arginine Catabolic Mobile Element in E,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16484,PHI:10471,UniProt,no data found,GenBank,,,,,ACME,,,,,,,1280,Staphylococcus aureus,,USA300 2406,skin infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,arginine catabolic mobile element,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32085445,PubMed,10.3390/microorganisms8020275,Microorganisms. 2020 Feb 18;8(2):275. doi: 10.3390/microorganisms8020275,kzhang@ucalgary.ca,"ACME did not contribute to bacterial virulence in cell invasion and cytotoxicity assays, invertebrate killing assays and a mouse skin infection model.",K Wu 2020,2020,2 genes,Wu-2020-Arginine Catabolic Mobile Element in E,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16485,PHI:10472,UniProt,H1UV33,GenBank,CCF31834,,,IMI 349063,CDC25 (CH063_04363),,,,Ras2,UniProt: H1V7E3; GenBank: CCF36145,,80884,Colletotrichum higginsianum,,CH-1,anthracnose,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,RasGEF domain-containing protein,,,cAMP signaling pathway,reduced virulence,,yes,yes,yes,,reduced,,reduced; aberrant,reduced,no,Congo red; SDS; H2O2; NaCl; sorbitol,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,32457707,PubMed,10.3389/fmicb.2020.00763,Front Microbiol. 2020 May 8;11:763. doi: 10.3389/fmicb.2020.00763. eCollection 2020,luzheng@mail.hzau.edu.cn,Deletion of ChCDC25 led to increased sensitivity to cell wall stress and resulted in resistance to osmotic stress.,Y Yan 2020,2020,1 gene,Yan-2020-ChCDC25 Regulates Infection-Related M,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16486,PHI:10473,UniProt,J9VNP9,GenBank,AFR93320,,,H99,Erg6 (CNAG_03819),chromosome 2,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,sterol C-24 methyltransferase,,,ergosterol biosynthesis,reduced virulence,,,,,,,,,,no,amphothericin B; fluconazole; itraconazole; ketoconazole; FK506; nystatin; cerulenin; brefeldin A; terbinafine; NaCl; KCl; calcofluor white; H2O2,amphothericin B: CHEBI:2682; fluconazole: CHEBI:46081; itraconazole: CHEBI:6076; ketoconazole: CHEBI:48336; FK506: CHEBI:61049; nystatin: CHEBI:7660; cerulenin: CHEBI:171741; brefeldin A: CHEBI:48080; terbinafine: CHEBI:9448; NaCl: CHEBI:26710; KCl: CHEBI:32588; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32201128,PubMed,10.1016/j.fgb.2020.103368,Fungal Genet Biol. 2020 Jul;140:103368. doi: 10.1016/j.fgb.2020.103368. Epub 2020 Mar 19,larissaf@unb.br,"The erg6 mutant displayed impaired thermotolerance and increased susceptibility to osmotic and oxidative stress, as well as to different antifungal drugs.",F F M Oliveira 2020,2020,1 gene,Oliveira-2020-Erg6 affects membrane compositio,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16487,PHI:10473,UniProt,J9VNP9,GenBank,AFR93320,,,H99,Erg6 (CNAG_03819),chromosome 2,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,sterol C-24 methyltransferase,,,ergosterol biosynthesis,reduced virulence,,,,,,,,,,no,amphothericin B; fluconazole; itraconazole; ketoconazole; FK506; nystatin; cerulenin; brefeldin A; terbinafine; NaCl; KCl; calcofluor white; H2O2,amphothericin B: CHEBI:2682; fluconazole: CHEBI:46081; itraconazole: CHEBI:6076; ketoconazole: CHEBI:48336; FK506: CHEBI:61049; nystatin: CHEBI:7660; cerulenin: CHEBI:171741; brefeldin A: CHEBI:48080; terbinafine: CHEBI:9448; NaCl: CHEBI:26710; KCl: CHEBI:32588; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32201128,PubMed,10.1016/j.fgb.2020.103368,Fungal Genet Biol. 2020 Jul;140:103368. doi: 10.1016/j.fgb.2020.103368. Epub 2020 Mar 19,larissaf@unb.br,"The erg6 mutant displayed impaired thermotolerance and increased susceptibility to osmotic and oxidative stress, as well as to different antifungal drugs.",F F M Oliveira 2020,2020,1 gene,Oliveira-2020-Erg6 affects membrane compositio,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16488,PHI:10474,UniProt,no data found,GenBank,ABO10946,,,ATCC 17978,Ctp (A1S_0493),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,bacteremia; meningitis; urinary tract infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,carboxy-terminal processing protease,,,,reduced virulence,,,,,,,,,,no,NaCl; triton X-100; H2O2,NaCl: CHEBI:26710; Triton X-100: CHEBI:9750; H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,32357487,PubMed,10.3390/pathogens9050322,Pathogens. 2020 Apr 26;9(5):322. doi: 10.3390/pathogens9050322,mingder@gms.tcu.edu.tw,"Mutation of the ctp gene reduced invasion and adhesion of A. baumannii to airway epithelial cells, potentially due to increased hydrophobicity.",R Roy 2020,2020,1 gene,Roy-2020-Mutation of the Carboxy-Terminal Proc,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16489,PHI:10474,UniProt,no data found,GenBank,ABO10946,,,ATCC 17978,Ctp (A1S_0493),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,bacteremia; meningitis; urinary tract infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,carboxy-terminal processing protease,,,,reduced virulence,,,,,,,,,,no,NaCl; triton X-100; H2O2,NaCl: CHEBI:26710; Triton X-100: CHEBI:9750; H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,32357487,PubMed,10.3390/pathogens9050322,Pathogens. 2020 Apr 26;9(5):322. doi: 10.3390/pathogens9050322,mingder@gms.tcu.edu.tw,"Mutation of the ctp gene reduced invasion and adhesion of A. baumannii to airway epithelial cells, potentially due to increased hydrophobicity.",R Roy 2020,2020,1 gene,Roy-2020-Mutation of the Carboxy-Terminal Proc,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16490,PHI:10475,UniProt,Q9PLC3,GenBank,AE002160,,,Nigg,GlgA,,S342F; H131Y,,,,,83560,Chlamydia muridarum,243161,Nigg,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,uterine cervix; uterine horn; oviduct; ovary,glycogen synthase A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,YVS,32533831,PubMed,10.1093/femspd/ftaa027,Pathog Dis. 2020 Jun 13:ftaa027. doi: 10.1093/femspd/ftaa027. Online ahead of print,liuyuanjun1980@126.com,"Glycogen synthase A-deficient Chlamydia muridarum induced reduction of hydrosalpinx and attenuated the extent of oviduct dilatation in mice, and exhibited reduced growth and proliferation in the mouse lower genital tract.",C Hu 2020,2020,1 gene,Hu-2020-GlgA plays an important role in the in,BATCH_101B,2020-07-01,MC,,,,,,,,,,,,,
,,Record 16491,PHI:10476,UniProt,J9VW97,GenBank,AFR98518,,,H99,liv4 (CNAG_06283),chromosome 13,,,,,,5207,Cryptococcus neoformans,1298968,H99,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; spleen; macrophage,transcription factor,,,,reduced virulence,,,,,,,reduced,,,no,H2O2; NaNO2,H2O2: CHEBI:16240; NaNO2: CHEBI:78870,,,,,gene deletion: full; gene complementation,,,YVS,32391887,PubMed,10.1093/femsyr/foaa015,FEMS Yeast Res. 2020 May 1;20(3):foaa015. doi: 10.1093/femsyr/foaa015,guizhen-wang@163.com,"Deletion of TF Liv4 protein resulted in growth defect under both normal and stress conditions (such as high temperature and cell wall/membrane damaging agents), drastic morphological damage and also attenuated virulence in C. neoformans.",J Yi 2020,2020,1 gene,Yi-2020-Transcription factor Liv4 is required,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16492,PHI:10476,UniProt,J9VW97,GenBank,AFR98518,,,H99,liv4 (CNAG_06283),chromosome 13,,,,,,5207,Cryptococcus neoformans,1298968,H99,meningoencephalitis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,transcription factor,,,,reduced virulence,,,,,,,reduced,,,no,H2O2; NaNO2,H2O2: CHEBI:16240; NaNO2: CHEBI:78870,,,,,gene deletion: full; gene complementation,,,YVS,32391887,PubMed,10.1093/femsyr/foaa015,FEMS Yeast Res. 2020 May 1;20(3):foaa015. doi: 10.1093/femsyr/foaa015,guizhen-wang@163.com,"Deletion of TF Liv4 protein resulted in growth defect under both normal and stress conditions (such as high temperature and cell wall/membrane damaging agents), drastic morphological damage and also attenuated virulence in C. neoformans.",J Yi 2020,2020,1 gene,Yi-2020-Transcription factor Liv4 is required,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16493,PHI:10477,UniProt,A0A0H2ZL68,GenBank,ABJ53701,,,D39,spd1495,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical ABC sugar-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32098834,PubMed,10.1128/mSystems.00025-20,mSystems. 2020 Feb 25;5(1):e00025-20. doi: 10.1128/mSystems.00025-20,tsunxs@jnu.edu.cn,"Knockout of spd1495 resulted in increased capsular polysaccharide synthesis, as well as increased bacterial virulence.",Y D Zheng 2020,2020,1 gene,Zheng-2020-SPD_1495 Contributes to Capsular Po,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16494,PHI:10477,UniProt,A0A0H2ZL68,GenBank,ABJ53701,,,D39,spd1495,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,hypothetical ABC sugar-binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32098834,PubMed,10.1128/mSystems.00025-20,mSystems. 2020 Feb 25;5(1):e00025-20. doi: 10.1128/mSystems.00025-20,tsunxs@jnu.edu.cn,"Knockout of spd1495 resulted in increased capsular polysaccharide synthesis, as well as increased bacterial virulence.",Y D Zheng 2020,2020,1 gene,Zheng-2020-SPD_1495 Contributes to Capsular Po,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16495,PHI:10478,UniProt,A0A0H3NK84,GenBank,CBW20184,,,SL1344,sseK1,,,,,,PHI:10479; PHI:10480,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32504010,PubMed,10.1038/s42003-020-1005-2,Commun Biol. 2020 Jun 5;3(1):287. doi: 10.1038/s42003-020-1005-2,lishan@mail.hzau.edu.cn,The arginine GlcNAc transferase activity of SseK3 was required for the replication of Salmonella in RAW264.7 macrophages and bacterial virulence in the mouse model of Salmonella infection.,K Meng 2020,2020,3 genes,Meng-2020-Arginine GlcNAcylation of Rab small,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16496,PHI:10479,UniProt,A0A0H3NIW0,GenBank,CBW18209,,,SL1344,sseK2,,,,,,PHI:10478; PHI:10480,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32504010,PubMed,10.1038/s42003-020-1005-2,Commun Biol. 2020 Jun 5;3(1):287. doi: 10.1038/s42003-020-1005-2,lishan@mail.hzau.edu.cn,The arginine GlcNAc transferase activity of SseK3 was required for the replication of Salmonella in RAW264.7 macrophages and bacterial virulence in the mouse model of Salmonella infection.,K Meng 2020,2020,3 genes,Meng-2020-Arginine GlcNAcylation of Rab small,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16497,PHI:10480,UniProt,A0A0H3NMP8,GenBank,CBW18025,,,SL1344,sseK3,,,,,,PHI:10478; PHI:10479,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32504010,PubMed,10.1038/s42003-020-1005-2,Commun Biol. 2020 Jun 5;3(1):287. doi: 10.1038/s42003-020-1005-2,lishan@mail.hzau.edu.cn,The arginine GlcNAc transferase activity of SseK3 was required for the replication of Salmonella in RAW264.7 macrophages and bacterial virulence in the mouse model of Salmonella infection.,K Meng 2020,2020,3 genes,Meng-2020-Arginine GlcNAcylation of Rab small,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16498,PHI:10478,UniProt,A0A0H3NK84,GenBank,CBW20184,,,SL1344,sseK1,,,,,,PHI:10479; PHI:10480,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32504010,PubMed,10.1038/s42003-020-1005-2,Commun Biol. 2020 Jun 5;3(1):287. doi: 10.1038/s42003-020-1005-2,lishan@mail.hzau.edu.cn,The arginine GlcNAc transferase activity of SseK3 was required for the replication of Salmonella in RAW264.7 macrophages and bacterial virulence in the mouse model of Salmonella infection.,K Meng 2020,2020,3 genes,Meng-2020-Arginine GlcNAcylation of Rab small,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16499,PHI:10479,UniProt,A0A0H3NIW0,GenBank,CBW18209,,,SL1344,sseK2,,,,,,PHI:10478; PHI:10480,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32504010,PubMed,10.1038/s42003-020-1005-2,Commun Biol. 2020 Jun 5;3(1):287. doi: 10.1038/s42003-020-1005-2,lishan@mail.hzau.edu.cn,The arginine GlcNAc transferase activity of SseK3 was required for the replication of Salmonella in RAW264.7 macrophages and bacterial virulence in the mouse model of Salmonella infection.,K Meng 2020,2020,3 genes,Meng-2020-Arginine GlcNAcylation of Rab small,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16500,PHI:10480,UniProt,A0A0H3NMP8,GenBank,CBW18025,,,SL1344,sseK3,,,,,,PHI:10478; PHI:10479,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32504010,PubMed,10.1038/s42003-020-1005-2,Commun Biol. 2020 Jun 5;3(1):287. doi: 10.1038/s42003-020-1005-2,lishan@mail.hzau.edu.cn,The arginine GlcNAc transferase activity of SseK3 was required for the replication of Salmonella in RAW264.7 macrophages and bacterial virulence in the mouse model of Salmonella infection.,K Meng 2020,2020,3 genes,Meng-2020-Arginine GlcNAcylation of Rab small,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16501,PHI:10478,UniProt,A0A0H3NK84,GenBank,CBW20184,,,SL1344,sseK1,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HEK293T cell line,,,embryonic kidney cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,other evidence: ectopic expression,,,YVS,32504010,PubMed,10.1038/s42003-020-1005-2,Commun Biol. 2020 Jun 5;3(1):287. doi: 10.1038/s42003-020-1005-2,lishan@mail.hzau.edu.cn,The arginine GlcNAc transferase activity of SseK3 was required for the replication of Salmonella in RAW264.7 macrophages and bacterial virulence in the mouse model of Salmonella infection.,K Meng 2020,2020,3 genes,Meng-2020-Arginine GlcNAcylation of Rab small,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16502,PHI:10480,UniProt,A0A0H3NMP8,GenBank,CBW18025,,,SL1344,sseK3,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),HEK293T cell line,,,embryonic kidney cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,other evidence: ectopic expression,,,YVS,32504010,PubMed,10.1038/s42003-020-1005-2,Commun Biol. 2020 Jun 5;3(1):287. doi: 10.1038/s42003-020-1005-2,lishan@mail.hzau.edu.cn,The arginine GlcNAc transferase activity of SseK3 was required for the replication of Salmonella in RAW264.7 macrophages and bacterial virulence in the mouse model of Salmonella infection.,K Meng 2020,2020,3 genes,Meng-2020-Arginine GlcNAcylation of Rab small,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16503,PHI:10481,UniProt,I1RBC0,GenBank,CEF72842,,,PH-1,sey1 (FGSG_00833),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spike; coleoptile,dynamin-like GTPase protein,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,sorbitol; NaCl; KCl; CaCl2; H2O2; SDS; Congo red,sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32220839,PubMed,10.1128/AEM.02720-19,Appl Environ Microbiol. 2020 May 19;86(11):e02720-19. doi: 10.1128/AEM.02720-19. Print 2020 May 19,zouss@sdau.edu.cn,"GTPase activity of FgSey1 was essential for vegetative growth, pathogenicity, and LD formation.",X Chong 2020,2020,1 gene,Chong-2020-The Dynamin-Like GTPase FgSey1 Play,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16504,PHI:10481,UniProt,I1RBC0,GenBank,CEF72842,,,PH-1,sey1 (FGSG_00833),chromosome 1,FgSey1K63A; FgSey1T87A,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,coleoptile,dynamin-like GTPase protein,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,sorbitol; NaCl; KCl; CaCl2; H2O2; SDS; Congo red,sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene mutation,,,YVS,32220839,PubMed,10.1128/AEM.02720-19,Appl Environ Microbiol. 2020 May 19;86(11):e02720-19. doi: 10.1128/AEM.02720-19. Print 2020 May 19,zouss@sdau.edu.cn,"GTPase activity of FgSey1 was essential for vegetative growth, pathogenicity, and LD formation.",X Chong 2020,2020,1 gene,Chong-2020-The Dynamin-Like GTPase FgSey1 Play,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16505,PHI:10481,UniProt,I1RBC0,GenBank,CEF72842,,,PH-1,sey1 (FGSG_00833),chromosome 1,FgSey1A644V,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,coleoptile,dynamin-like GTPase protein,,,deoxynivalenol biosynthesis,unaffected pathogenicity,,,,,,reduced; aberrant,,reduced; aberrant,,no,sorbitol; NaCl; KCl; CaCl2; H2O2; SDS; Congo red,sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene mutation,,,YVS,32220839,PubMed,10.1128/AEM.02720-19,Appl Environ Microbiol. 2020 May 19;86(11):e02720-19. doi: 10.1128/AEM.02720-19. Print 2020 May 19,zouss@sdau.edu.cn,"GTPase activity of FgSey1 was essential for vegetative growth, pathogenicity, and LD formation.",X Chong 2020,2020,1 gene,Chong-2020-The Dynamin-Like GTPase FgSey1 Play,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16506,PHI:10482,UniProt,Q1JIA8,GenBank,ABF33415,,,MGAS10270,spyA,,,,,,,1314,Streptococcus pyogenes,,MGAS27961,vaginal infection; necrotizing myositis; uterine wall infection,primates,9541,Macaca fascicularis (related: crab-eating macaque),,,,vagina; uterus; skeletal muscle,C3 family ADP-ribosyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32200972,PubMed,10.1016/j.ajpath.2019.12.003,Am J Pathol. 2020 Apr;190(4):862-873. doi: 10.1016/j.ajpath.2019.12.003. Epub 2020 Mar 19,jmmusser@houstonmethodist. org,Isogenic mutant strains ΔspyAD and Δisp2 are significantly impaired in ability to colonize the primate genital tract and cause uterine wall pathologic findings.,L Zhu 2020,2020,3 genes,Zhu-2020-Genome-Wide Screens Identify Group A,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16507,PHI:10483,UniProt,no data found,GenBank,,,,,spyD,,,,,,,1314,Streptococcus pyogenes,,MGAS27961,vaginal infection; necrotizing myositis; uterine wall infection,primates,9541,Macaca fascicularis (related: crab-eating macaque),,,,vagina; uterus; skeletal muscle,surface-exclusion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32200972,PubMed,10.1016/j.ajpath.2019.12.003,Am J Pathol. 2020 Apr;190(4):862-873. doi: 10.1016/j.ajpath.2019.12.003. Epub 2020 Mar 19,jmmusser@houstonmethodist. org,Isogenic mutant strains ΔspyAD and Δisp2 are significantly impaired in ability to colonize the primate genital tract and cause uterine wall pathologic findings.,L Zhu 2020,2020,3 genes,Zhu-2020-Genome-Wide Screens Identify Group A,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16508,PHI:10484,UniProt,J7MB23,GenBank,BAM30927,,,,isp2,,,,,,,1314,Streptococcus pyogenes,,MGAS27961,vaginal infection; necrotizing myositis; uterine wall infection,primates,9541,Macaca fascicularis (related: crab-eating macaque),,,,vagina; uterus; skeletal muscle,immunogenic secreted protein 2,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32200972,PubMed,10.1016/j.ajpath.2019.12.003,Am J Pathol. 2020 Apr;190(4):862-873. doi: 10.1016/j.ajpath.2019.12.003. Epub 2020 Mar 19,jmmusser@houstonmethodist. org,Isogenic mutant strains ΔspyAD and Δisp2 are significantly impaired in ability to colonize the primate genital tract and cause uterine wall pathologic findings.,L Zhu 2020,2020,3 genes,Zhu-2020-Genome-Wide Screens Identify Group A,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16509,PHI:10485,UniProt,Q9HV44,GenBank,AE004889_9,,,PAO1,dnaJ,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,opportunistic infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,heat shock protein,,,pyocyanin production,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,32178243,PubMed,10.3390/microorganisms8030395,Microorganisms. 2020 Mar 12;8(3):395. doi: 10.3390/microorganisms8030395,zengbo6201@gmail.com,"A dnaJ mutant produced hardly any pyocyanin and formed significantly less biofilms, which contributed to decreased pathogenicity.",B Zeng 2020,2020,1 gene,Zeng-2020-Heat Shock Protein DnaJ in Pseudomon,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16510,PHI:10486,UniProt,no data found,GenBank,WP_011259198,,,,rpoN2,,,,Uniprot: A0A0K0GIH5; Genbank: ACD58129; Uniprot: A0A0K0GMM5; Genbank: ACD60058,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,σ54 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32112711,PubMed,10.1111/mpp.12920,Mol Plant Pathol. 2020 May;21(5):652-666. doi: 10.1111/mpp.12920. Epub 2020 Feb 29,chenhuamin@caas.cn,"RpoN2, PilRX, PilAX, and PilCX genes positively regulated biofilm formation and were required for twitching and swimming motility in Xanthomonas oryzae pv. oryzae.",C Yu 2020,2020,5 genes,Yu-2020-The RpoN2-PilRX regulatory system gove,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16511,PHI:10487,UniProt,A0A0K0GIH5,GenBank,ACD58129,,,PXO99A,pilR (PXO_04881),,,,Uniprot: no data found; Genbank: WP_011259198,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32112711,PubMed,10.1111/mpp.12920,Mol Plant Pathol. 2020 May;21(5):652-666. doi: 10.1111/mpp.12920. Epub 2020 Feb 29,chenhuamin@caas.cn,"RpoN2, PilRX, PilAX, and PilCX genes positively regulated biofilm formation and were required for twitching and swimming motility in Xanthomonas oryzae pv. oryzae.",C Yu 2020,2020,5 genes,Yu-2020-The RpoN2-PilRX regulatory system gove,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16512,PHI:10488,UniProt,A0A0K0GMM5,GenBank,ACD60058,,,PXO99A,pilX (PXO_01323),,,,Uniprot: no data found; Genbank: WP_011259198,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,minor pilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32112711,PubMed,10.1111/mpp.12920,Mol Plant Pathol. 2020 May;21(5):652-666. doi: 10.1111/mpp.12920. Epub 2020 Feb 29,chenhuamin@caas.cn,"RpoN2, PilRX, PilAX, and PilCX genes positively regulated biofilm formation and were required for twitching and swimming motility in Xanthomonas oryzae pv. oryzae.",C Yu 2020,2020,5 genes,Yu-2020-The RpoN2-PilRX regulatory system gove,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16513,PHI:10489,UniProt,A0A0K0GIS0,GenBank,ACD58122,,,PXO99A,pilA (PXO_04886),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,major pilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32112711,PubMed,10.1111/mpp.12920,Mol Plant Pathol. 2020 May;21(5):652-666. doi: 10.1111/mpp.12920. Epub 2020 Feb 29,chenhuamin@caas.cn,"RpoN2, PilRX, PilAX, and PilCX genes positively regulated biofilm formation and were required for twitching and swimming motility in Xanthomonas oryzae pv. oryzae.",C Yu 2020,2020,5 genes,Yu-2020-The RpoN2-PilRX regulatory system gove,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16514,PHI:10488,UniProt,A0A0K0GMM5,GenBank,ACD60058,,,PXO99A,pilX (PXO_01323),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,minor pilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32112711,PubMed,10.1111/mpp.12920,Mol Plant Pathol. 2020 May;21(5):652-666. doi: 10.1111/mpp.12920. Epub 2020 Feb 29,chenhuamin@caas.cn,"RpoN2, PilRX, PilAX, and PilCX genes positively regulated biofilm formation and were required for twitching and swimming motility in Xanthomonas oryzae pv. oryzae.",C Yu 2020,2020,5 genes,Yu-2020-The RpoN2-PilRX regulatory system gove,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16515,PHI:10490,UniProt,A0A0K0GIM7,GenBank,ACD58121,,,PXO99A,PilC (PXO_04887),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,pilin biogenesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32112711,PubMed,10.1111/mpp.12920,Mol Plant Pathol. 2020 May;21(5):652-666. doi: 10.1111/mpp.12920. Epub 2020 Feb 29,chenhuamin@caas.cn,"RpoN2, PilRX, PilAX, and PilCX genes positively regulated biofilm formation and were required for twitching and swimming motility in Xanthomonas oryzae pv. oryzae.",C Yu 2020,2020,5 genes,Yu-2020-The RpoN2-PilRX regulatory system gove,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16516,PHI:10488,UniProt,A0A0K0GMM5,GenBank,ACD60058,,,PXO99A,pilX (PXO_01323),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,minor pilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32112711,PubMed,10.1111/mpp.12920,Mol Plant Pathol. 2020 May;21(5):652-666. doi: 10.1111/mpp.12920. Epub 2020 Feb 29,chenhuamin@caas.cn,"RpoN2, PilRX, PilAX, and PilCX genes positively regulated biofilm formation and were required for twitching and swimming motility in Xanthomonas oryzae pv. oryzae.",C Yu 2020,2020,5 genes,Yu-2020-The RpoN2-PilRX regulatory system gove,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16517,PHI:10491,UniProt,no data found,GenBank,,,,,Exl1,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,soft rot (potato); blackleg disease (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,petiole; tuber,expansin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32385404,PubMed,10.1038/s41598-020-64529-9,Sci Rep. 2020 May 8;10(1):7747. doi: 10.1038/s41598-020-64529-9,cma@ibt.unam.mx,"ΔExl1 exhibiting less maceration of potato plants, fewer bacteria were observed at distance from the inoculation site.",D A Narvaez-Barraga 2020,2020,1 gene,Narvaez-Barraga-2020-Expansin-like Exl1 from P,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16518,PHI:10492,UniProt,no data found,GenBank,,,,,Exl1,,,,,,,180957,Pectobacterium brasiliense,,BF45,grey mold,eudicots,4113,Solanum tuberosum (related: potato),,,,petiole; tuber,expansin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32385404,PubMed,10.1038/s41598-020-64529-9,Sci Rep. 2020 May 8;10(1):7747. doi: 10.1038/s41598-020-64529-9,cma@ibt.unam.mx,"ΔExl1 exhibiting less maceration of potato plants, fewer bacteria were observed at distance from the inoculation site.",D A Narvaez-Barraga 2020,2020,1 gene,Narvaez-Barraga-2020-Expansin-like Exl1 from P,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16519,PHI:10491,UniProt,no data found,GenBank,,,,,Exl1,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI 1043,soft rot (potato); blackleg disease (potato),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,expansin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32385404,PubMed,10.1038/s41598-020-64529-9,Sci Rep. 2020 May 8;10(1):7747. doi: 10.1038/s41598-020-64529-9,cma@ibt.unam.mx,"ΔExl1 exhibiting less maceration of potato plants, fewer bacteria were observed at distance from the inoculation site.",D A Narvaez-Barraga 2020,2020,1 gene,Narvaez-Barraga-2020-Expansin-like Exl1 from P,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16520,PHI:10492,UniProt,no data found,GenBank,,,,,Exl1,,,,,,,180957,Pectobacterium brasiliense,,BF45,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,expansin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32385404,PubMed,10.1038/s41598-020-64529-9,Sci Rep. 2020 May 8;10(1):7747. doi: 10.1038/s41598-020-64529-9,cma@ibt.unam.mx,"ΔExl1 exhibiting less maceration of potato plants, fewer bacteria were observed at distance from the inoculation site.",D A Narvaez-Barraga 2020,2020,1 gene,Narvaez-Barraga-2020-Expansin-like Exl1 from P,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16521,PHI:10492,UniProt,no data found,GenBank,,,,,Exl1,,,,,,,180957,Pectobacterium brasiliense,,BF45,grey mold,eudicots,4045,Apium graveolens (no common name found),,,,petiole,expansin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32385404,PubMed,10.1038/s41598-020-64529-9,Sci Rep. 2020 May 8;10(1):7747. doi: 10.1038/s41598-020-64529-9,cma@ibt.unam.mx,Increased celery tissue maceration by exl1 over-expression (OE) was observed in P. brasiliense BF45.,D A Narvaez-Barraga 2020,2020,1 gene,Narvaez-Barraga-2020-Expansin-like Exl1 from P,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16522,PHI:10493,,no data found,GenBank,EYB23554,,,CS3005,Fgank1 (FG05_02877),,,,FgZC1 (FG05_05068),UniProt: no data found; GenBank: EYB23554,,5518,Fusarium graminearum,1450154,CS3005,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),,,,root,ankyrin-repeat domain containing protein,,,nitric oxide synthesis,reduced virulence,,,,,,,,aberrant,,no,NaCl; H2O2; calcofluor white,NaCl: CHEBI:26710; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,32376629,PubMed,10.1073/pnas.1918977117,Proc Natl Acad Sci U S A. 2020 May 19;117(20):11147-11157. doi: 10.1073/pnas.1918977117. Epub 2020 May 6,kazan@csiro.au,"Disruption of the ankyrin domain region of FgANK1 resulted in a loss of interaction capability, and consequently impaired NO production.",Y Ding 2020,2020,2 genes,Ding-2020-Regulators of nitric oxide signaling,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16523,PHI:10494,UniProt,A0A0E0SMG6,GenBank,EYB31819,,,CS3005,FgZC1 (FG05_05068),,,,Fgank1 (FG05_02877),UniProt: no data found; GenBank: EYB31819,,5518,Fusarium graminearum,1450154,CS3005,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),,,,root,zinc finger transcription factor,,,nitric oxide synthesis,reduced virulence,,,,,,,,wild type,,no,NaCl; H2O2; calcofluor white,NaCl: CHEBI:26710; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,32376629,PubMed,10.1073/pnas.1918977117,Proc Natl Acad Sci U S A. 2020 May 19;117(20):11147-11157. doi: 10.1073/pnas.1918977117. Epub 2020 May 6,kazan@csiro.au,"Disruption of the ankyrin domain region of FgANK1 resulted in a loss of interaction capability, and consequently impaired NO production.",Y Ding 2020,2020,2 genes,Ding-2020-Regulators of nitric oxide signaling,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16524,PHI:10495,UniProt,A0A6C7HN39,GenBank,CAR32591,,,P125109,SEN1008,,,,,,,28901,Salmonella enterica,550537,subsp. enterica serovar Enteritidis strain P125109,salmonellosis; colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,mesenteric lymph node; spleen; liver; cecum,putative exported protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32116124,PubMed,10.1080/21505594.2020.1733203,Virulence. 2020 Dec;11(1):247-259. doi: 10.1080/21505594.2020.1733203,msbiotek@yahoo.com,The isogenic mutant strain displayed reduced adhesion to epithelial cells in vitro as well as was highly immotile.,S Das 2020,2020,1 gene,Das-2020-A ROD9 island encoded gene in Salmone,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16525,PHI:10495,UniProt,A0A6C7HN39,GenBank,CAR32591,,,P125109,SEN1008,,,,,,,28901,Salmonella enterica,550537,subsp. enterica serovar Enteritidis strain P125109,salmonellosis; colitis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,HCT-116 cell,putative exported protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32116124,PubMed,10.1080/21505594.2020.1733203,Virulence. 2020 Dec;11(1):247-259. doi: 10.1080/21505594.2020.1733203,msbiotek@yahoo.com,The isogenic mutant strain displayed reduced adhesion to epithelial cells in vitro as well as was highly immotile.,S Das 2020,2020,1 gene,Das-2020-A ROD9 island encoded gene in Salmone,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16526,PHI:10495,UniProt,A0A6C7HN39,GenBank,CAR32591,,,P125109,SEN1008,,,,,,,28901,Salmonella enterica,550537,subsp. enterica serovar Enteritidis strain P125109,salmonellosis; colitis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative exported protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32116124,PubMed,10.1080/21505594.2020.1733203,Virulence. 2020 Dec;11(1):247-259. doi: 10.1080/21505594.2020.1733203,msbiotek@yahoo.com,The isogenic mutant strain displayed reduced adhesion to epithelial cells in vitro as well as was highly immotile.,S Das 2020,2020,1 gene,Das-2020-A ROD9 island encoded gene in Salmone,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16527,PHI:10496,UniProt,A0A6B9WEF9,GenBank,QHQ96671,,,Bmpc7,Ofd1,,,,,,,38448,Monilinia fructicola,,Bmpc7,blossom blight; twig canker; fruit rot,eudicots,3760,Prunus persica (related: peach),cv. Fei Cheng,,,fruit,oxidoreductase,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,H2O2; glycerol; D-sorbitol; NaCl; iprodione; dimethachlon; SDS; Congo red; MgSO4,H2O2: CHEBI:16240; glycerol: CHEBI:17754; D-sorbitol: CHEBI:30911; NaCl: CHEBI:26710; iprodione: CHEBI:28909; dimethachlone CAS no.: CAS:24096-53-5; SDS: CHEBI:8984; Congo red: CHEBI:34653; MgSO4: CHEBI:32599,,,,,gene deletion: full,,,YVS,32319202,PubMed,10.1111/mpp.12933,Mol Plant Pathol. 2020 Jun;21(6):820-833. doi: 10.1111/mpp.12933. Epub 2020 Apr 21,luo@mail.hzau.edu.cn,"MfOfd1 gene played an important role in M. fructicola in sporulation, oxidative response, osmotic stress tolerance, and virulence.",M M Zhang 2020,2020,1 gene,Zhang-2020-MfOfd1 is crucial for stress respon,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16528,PHI:10497,UniProt,no data found,GenBank,,,,,CvpF,,,,,,,777,Coxiella burnetii,,Nine Mile phase II,zoonotic Q fever,rodents,10090,Mus musculus (related: house mouse),C.B-17IcrHsd-Prkdc<scid>,,,spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32116095,PubMed,10.1080/15548627.2020.1728098,Autophagy. 2020 Mar 1:1-17. doi: 10.1080/15548627.2020.1728098. Online ahead of print,matteo.bonazzi@irim.cnrs.fr,"CvpF::Tn mutants were highly attenuated compared to wild-type bacteria in the SCID mouse model of infection, suggesting that CvpF manipulated endosomal trafficking and macroautophagy/autophagy induction for optimal C. burnetii vacuole biogenesis.",F A Siadous 2020,2020,1 gene,Siadous-2020-Coxiella effector protein CvpF su,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16529,PHI:10497,UniProt,no data found,GenBank,,,,,CvpF,,,,,,,777,Coxiella burnetii,,Nine Mile phase II,zoonotic Q fever,primates,9606,Homo sapiens (related: human),U2OS,,,U2-OS cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32116095,PubMed,10.1080/15548627.2020.1728098,Autophagy. 2020 Mar 1:1-17. doi: 10.1080/15548627.2020.1728098. Online ahead of print,matteo.bonazzi@irim.cnrs.fr,"CvpF::Tn mutants were highly attenuated compared to wild-type bacteria in the SCID mouse model of infection, suggesting that CvpF manipulated endosomal trafficking and macroautophagy/autophagy induction for optimal C. burnetii vacuole biogenesis.",F A Siadous 2020,2020,1 gene,Siadous-2020-Coxiella effector protein CvpF su,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16530,PHI:10497,UniProt,no data found,GenBank,,,,,CvpF,,,,,,,777,Coxiella burnetii,,Nine Mile phase II,zoonotic Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32116095,PubMed,10.1080/15548627.2020.1728098,Autophagy. 2020 Mar 1:1-17. doi: 10.1080/15548627.2020.1728098. Online ahead of print,matteo.bonazzi@irim.cnrs.fr,"CvpF::Tn mutants were highly attenuated compared to wild-type bacteria in the SCID mouse model of infection, suggesting that CvpF manipulated endosomal trafficking and macroautophagy/autophagy induction for optimal C. burnetii vacuole biogenesis.",F A Siadous 2020,2020,1 gene,Siadous-2020-Coxiella effector protein CvpF su,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16531,PHI:10500,UniProt,Q8XXX7,GenBank,CAD15688,,,GMI1000,tapV (Rsc1986),,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,probable type iv pilus assembly fimv-related transmembrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32196936,PubMed,10.1111/mpp.12930,Mol Plant Pathol. 2020 Jun;21(6):777-793. doi: 10.1111/mpp.12930. Epub 2020 Mar 20,kouheio@kochi-u.ac.jp,"TapV is important for T4p-dependent swimming motility and root adherence, but negatively affects biofilm information in R. solanacearum",Y Zhang 2020,2020,3 genes,Zhang-2020-Expression of Ralstonia solanacearu,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16532,PHI:10500,UniProt,Q8XXX7,GenBank,CAD15688,,,GMI1000,tapV (Rsc1986),,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,probable type iv pilus assembly fimv-related transmembrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32196936,PubMed,10.1111/mpp.12930,Mol Plant Pathol. 2020 Jun;21(6):777-793. doi: 10.1111/mpp.12930. Epub 2020 Mar 20,kouheio@kochi-u.ac.jp,"TapV is important for T4p-dependent swimming motility and root adherence, but negatively affects biofilm information in R. solanacearum",Y Zhang 2020,2020,3 genes,Zhang-2020-Expression of Ralstonia solanacearu,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16533,PHI:10501,UniProt,A0A0S4V9F3,GenBank,CUV17790,,,Phyl III-seqv23,pilA,chromosome 3,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,type 4 fimbrial pilin signal peptide protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32196936,PubMed,10.1111/mpp.12930,Mol Plant Pathol. 2020 Jun;21(6):777-793. doi: 10.1111/mpp.12930. Epub 2020 Mar 20,kouheio@kochi-u.ac.jp,"TapV is important for T4p-dependent swimming motility and root adherence, but negatively affects biofilm information in R. solanacearum",Y Zhang 2020,2020,3 genes,Zhang-2020-Expression of Ralstonia solanacearu,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16534,PHI:10501,UniProt,A0A0S4V9F3,GenBank,CUV17790,,,Phyl III-seqv23,pilA,chromosome 3,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,type 4 fimbrial pilin signal peptide protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32196936,PubMed,10.1111/mpp.12930,Mol Plant Pathol. 2020 Jun;21(6):777-793. doi: 10.1111/mpp.12930. Epub 2020 Mar 20,kouheio@kochi-u.ac.jp,"TapV is important for T4p-dependent swimming motility and root adherence, but negatively affects biofilm information in R. solanacearum",Y Zhang 2020,2020,3 genes,Zhang-2020-Expression of Ralstonia solanacearu,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16535,PHI:10502,UniProt,Q8XTC4,GenBank,CAD17340,,,GMI1000,rsp0189,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,probable type iv pilus assembly fimv-related transmembrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32196936,PubMed,10.1111/mpp.12930,Mol Plant Pathol. 2020 Jun;21(6):777-793. doi: 10.1111/mpp.12930. Epub 2020 Mar 20,kouheio@kochi-u.ac.jp,"TapV is important for T4p-dependent swimming motility and root adherence, but negatively affects biofilm information in R. solanacearum",Y Zhang 2020,2020,3 genes,Zhang-2020-Expression of Ralstonia solanacearu,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16536,PHI:10502,UniProt,Q8XTC4,GenBank,CAD17340,,,GMI1000,rsp0189,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,probable type iv pilus assembly fimv-related transmembrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32196936,PubMed,10.1111/mpp.12930,Mol Plant Pathol. 2020 Jun;21(6):777-793. doi: 10.1111/mpp.12930. Epub 2020 Mar 20,kouheio@kochi-u.ac.jp,"TapV is important for T4p-dependent swimming motility and root adherence, but negatively affects biofilm information in R. solanacearum",Y Zhang 2020,2020,3 genes,Zhang-2020-Expression of Ralstonia solanacearu,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16537,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16538,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16539,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,PHI:10504,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16540,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,PHI:10503,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16541,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16542,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16543,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,PHI:10504,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16544,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,PHI:10503,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16545,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,Deletion of GRA15 and GRA24 led to enhanced parasite virulence in Tlr11-/- mice.,D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16546,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,Deletion of GRA15 and GRA24 led to enhanced parasite virulence in Tlr11-/- mice.,D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16547,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,PHI:10504,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,Deletion of GRA15 and GRA24 led to enhanced parasite virulence in Tlr11-/- mice.,D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16548,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,PHI:10503,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,Deletion of GRA15 and GRA24 led to enhanced parasite virulence in Tlr11-/- mice.,D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16549,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,foreskin fibroblast cell line,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16550,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,foreskin fibroblast cell line,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16551,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,PHI:10504,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,foreskin fibroblast cell line,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16552,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,PHI:10503,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,foreskin fibroblast cell line,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16553,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16554,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16555,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,PHI:10504,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16556,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,PHI:10503,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,"GRA15 was required for the secretion of IL1β and TNFα from BMDM, both GRA15 and GRA24 were required for the secretion of IL12/IL23p40.",D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16557,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,GRA15 and GRA24 induced cytokine secretion by human PBMCs.,D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16558,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,GRA15 and GRA24 induced cytokine secretion by human PBMCs.,D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16559,PHI:10503,UniProt,A0A125YGQ9,GenBank,EPT26400,,,ME49,GRA15,chromosome X,,,,,PHI:10504,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,GRA15 and GRA24 induced cytokine secretion by human PBMCs.,D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16560,PHI:10504,UniProt,A0A125YG37,GenBank,EPT29037,,,ME49,GRA24 (TgME49_230180),chromosome VIII,,,,,PHI:10503,5811,Toxoplasma gondii,1209523,type II,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,dense granule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32453782,PubMed,10.1371/journal.ppat.1008586,PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May,jsaeij@ucdavis.edu,GRA15 and GRA24 induced cytokine secretion by human PBMCs.,D Mukhopadhyay 2020,2020,2 genes,Mukhopadhyay-2020-Toxoplasma GRA15 and GRA24,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16561,PHI:10505,UniProt,Q9AJ23,GenBank,AF200363_14,,,RDEC-1,GrlA,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,locus of enterocyte effacement (LEE) transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32277032,PubMed,10.1073/pnas.1917500117,Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9519-9528. doi: 10.1073/pnas.1917500117. Epub 2020 Apr 10,Anne.Marie.Krachler@uth.tmc.edu,EHEC strains that harbored either grlA:ML1 grlA:ML2 mutations or a grlR deletion attached to epithelial cells significantly more than wild-type bacteria and EHEC ΔgrlA strain was hypoadherent.,N Sirisaengtaksin 2020,2020,2 genes,Sirisaengtaksin-2020-The E. coli transcription,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16562,PHI:10505,UniProt,Q9AJ23,GenBank,AF200363_14,,,RDEC-1,GrlA,,grlA:ML1 (K111A R114A),,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,locus of enterocyte effacement (LEE) transcriptional activator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32277032,PubMed,10.1073/pnas.1917500117,Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9519-9528. doi: 10.1073/pnas.1917500117. Epub 2020 Apr 10,Anne.Marie.Krachler@uth.tmc.edu,EHEC strains that harbored either grlA:ML1 grlA:ML2 mutations or a grlR deletion attached to epithelial cells significantly more than wild-type bacteria and EHEC ΔgrlA strain was hypoadherent.,N Sirisaengtaksin 2020,2020,2 genes,Sirisaengtaksin-2020-The E. coli transcription,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16563,PHI:10505,UniProt,Q9AJ23,GenBank,AF200363_14,,,RDEC-1,GrlA,,grlA:ML2 (R132A K135A),,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,locus of enterocyte effacement (LEE) transcriptional activator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32277032,PubMed,10.1073/pnas.1917500117,Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9519-9528. doi: 10.1073/pnas.1917500117. Epub 2020 Apr 10,Anne.Marie.Krachler@uth.tmc.edu,EHEC strains that harbored either grlA:ML1 grlA:ML2 mutations or a grlR deletion attached to epithelial cells significantly more than wild-type bacteria and EHEC ΔgrlA strain was hypoadherent.,N Sirisaengtaksin 2020,2020,2 genes,Sirisaengtaksin-2020-The E. coli transcription,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16564,PHI:10506,UniProt,Q9AJ24,GenBank,AF200363_13,,,RDEC-1,GrlR,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32277032,PubMed,10.1073/pnas.1917500117,Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9519-9528. doi: 10.1073/pnas.1917500117. Epub 2020 Apr 10,Anne.Marie.Krachler@uth.tmc.edu,EHEC strains that harbored either grlA:ML1 grlA:ML2 mutations or a grlR deletion attached to epithelial cells significantly more than wild-type bacteria and EHEC ΔgrlA strain was hypoadherent.,N Sirisaengtaksin 2020,2020,2 genes,Sirisaengtaksin-2020-The E. coli transcription,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16565,PHI:10505,UniProt,Q9AJ23,GenBank,AF200363_14,,,RDEC-1,GrlA,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,locus of enterocyte effacement (LEE) transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32277032,PubMed,10.1073/pnas.1917500117,Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9519-9528. doi: 10.1073/pnas.1917500117. Epub 2020 Apr 10,Anne.Marie.Krachler@uth.tmc.edu,"Both deletion strains (EHEC ΔgrlA and EHEC ΔgrlR) as well as both EHEC grlA:ML1 and grlA:ML2 strain, had significantly decreased bacterial burdens.",N Sirisaengtaksin 2020,2020,2 genes,Sirisaengtaksin-2020-The E. coli transcription,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16566,PHI:10505,UniProt,Q9AJ23,GenBank,AF200363_14,,,RDEC-1,GrlA,,grlA:ML1 (K111A R114A),,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,locus of enterocyte effacement (LEE) transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32277032,PubMed,10.1073/pnas.1917500117,Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9519-9528. doi: 10.1073/pnas.1917500117. Epub 2020 Apr 10,Anne.Marie.Krachler@uth.tmc.edu,"Both deletion strains (EHEC ΔgrlA and EHEC ΔgrlR) as well as both EHEC grlA:ML1 and grlA:ML2 strain, had significantly decreased bacterial burdens.",N Sirisaengtaksin 2020,2020,2 genes,Sirisaengtaksin-2020-The E. coli transcription,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16567,PHI:10505,UniProt,Q9AJ23,GenBank,AF200363_14,,,RDEC-1,GrlA,,grlA:ML2 (R132A K135A),,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,locus of enterocyte effacement (LEE) transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32277032,PubMed,10.1073/pnas.1917500117,Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9519-9528. doi: 10.1073/pnas.1917500117. Epub 2020 Apr 10,Anne.Marie.Krachler@uth.tmc.edu,"Both deletion strains (EHEC ΔgrlA and EHEC ΔgrlR) as well as both EHEC grlA:ML1 and grlA:ML2 strain, had significantly decreased bacterial burdens.",N Sirisaengtaksin 2020,2020,2 genes,Sirisaengtaksin-2020-The E. coli transcription,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16568,PHI:10506,UniProt,Q9AJ24,GenBank,AF200363_13,,,RDEC-1,GrlR,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32277032,PubMed,10.1073/pnas.1917500117,Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9519-9528. doi: 10.1073/pnas.1917500117. Epub 2020 Apr 10,Anne.Marie.Krachler@uth.tmc.edu,"Both deletion strains (EHEC ΔgrlA and EHEC ΔgrlR) as well as both EHEC grlA:ML1 and grlA:ML2 strain, had significantly decreased bacterial burdens.",N Sirisaengtaksin 2020,2020,2 genes,Sirisaengtaksin-2020-The E. coli transcription,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16569,PHI:10507,UniProt,E9DWQ2,GenBank,EFY91765,,,CQMa 102,Sho1 (MAC_02050),,,,,,,92637,Metarhizium acridum,,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,nymph,transmembrane protein,,,,reduced virulence,,yes,,,,increased,,,wild type,no,Congo red; calcofluor white; sodium dodecyl sulphate; menadione; sorbitol; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulphate: CHEBI:8984; menadione: CHEBI:28869; sorbitol: CHEBI:30911; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,32170386,PubMed,10.1007/s00253-020-10523-0,Appl Microbiol Biotechnol. 2020 May;104(9):4005-4015. doi: 10.1007/s00253-020-10523-0. Epub 2020 Mar 13,jinkai@cqu.edu.cn,"Targeted gene disruption of MaSho1 impaired cell wall integrity, virulence, and tolerances to UV-B and oxidative stresses, while none of them was affected when the SH3 domain was deleted.",T Zhao 2020,2020,1 gene,Zhao-2020-The transmembrane protein MaSho1 neg,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16570,PHI:10507,UniProt,E9DWQ2,GenBank,EFY91765,,,CQMa 102,Sho1 (MAC_02050),,MaSho1 ΔSH3,,,,,92637,Metarhizium acridum,,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,nymph,transmembrane protein,,,,unaffected pathogenicity,,yes,,,,wild type,,,wild type,no,Congo red; calcofluor white; sodium dodecyl sulphate; menadione; sorbitol; NaCl,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulphate: CHEBI:8984; menadione: CHEBI:28869; sorbitol: CHEBI:30911; NaCl: CHEBI:26710,,,,,gene mutation; gene complementation,,,YVS,32170386,PubMed,10.1007/s00253-020-10523-0,Appl Microbiol Biotechnol. 2020 May;104(9):4005-4015. doi: 10.1007/s00253-020-10523-0. Epub 2020 Mar 13,jinkai@cqu.edu.cn,"Targeted gene disruption of MaSho1 impaired cell wall integrity, virulence, and tolerances to UV-B and oxidative stresses, while none of them was affected when the SH3 domain was deleted.",T Zhao 2020,2020,1 gene,Zhao-2020-The transmembrane protein MaSho1 neg,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16571,PHI:10508,UniProt,no data found,GenBank,,,,,pecT,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),cv. Irga,,,tuber,negative global regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32068796,PubMed,10.1093/femsec/fiaa023,FEMS Microbiol Ecol. 2020 Mar 1;96(3):fiaa023. doi: 10.1093/femsec/fiaa023,marta.potrykus@gumed.edu.pl,PecT mutants had a higher maceration capacity of potato tissue and showed a higher pectinolytic activity than the wild-type strain.,M Potrykus 2020,2020,2 genes,Potrykus-2020-The metabolic shift in highly an,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16572,PHI:10509,UniProt,no data found,GenBank,,,,,expI,,,,,,,1089444,Dickeya solani,,IFB0223,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),cv. Irga,,,tuber,AHL synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32068796,PubMed,10.1093/femsec/fiaa023,FEMS Microbiol Ecol. 2020 Mar 1;96(3):fiaa023. doi: 10.1093/femsec/fiaa023,marta.potrykus@gumed.edu.pl,"Mutation in expI gene, had an insignificant effect on the cell metabolism, although it slightly reduced the potato tissue maceration.",M Potrykus 2020,2020,2 genes,Potrykus-2020-The metabolic shift in highly an,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16573,PHI:10508,UniProt,no data found,GenBank,,,,,pecT,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),cv. Irga,,,tuber,negative global regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32068796,PubMed,10.1093/femsec/fiaa023,FEMS Microbiol Ecol. 2020 Mar 1;96(3):fiaa023. doi: 10.1093/femsec/fiaa023,marta.potrykus@gumed.edu.pl,PecT mutants had a higher maceration capacity of potato tissue and showed a higher pectinolytic activity than the wild-type strain.,M Potrykus 2020,2020,2 genes,Potrykus-2020-The metabolic shift in highly an,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16574,PHI:10509,UniProt,no data found,GenBank,,,,,expI,,,,,,,1089444,Dickeya solani,,IFB0099,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),cv. Irga,,,tuber,AHL synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32068796,PubMed,10.1093/femsec/fiaa023,FEMS Microbiol Ecol. 2020 Mar 1;96(3):fiaa023. doi: 10.1093/femsec/fiaa023,marta.potrykus@gumed.edu.pl,"Mutation in expI gene, had an insignificant effect on the cell metabolism, although it slightly reduced the potato tissue maceration.",M Potrykus 2020,2020,2 genes,Potrykus-2020-The metabolic shift in highly an,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16575,PHI:10510,UniProt,A0A505MF50,GenBank,TPS01751,,,MRSN7460,ggt,,,,,,,470,Acinetobacter baumannii,,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; kidney,gamma-glutamyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32421167,PubMed,10.1093/infdis/jiaa262,J Infect Dis. 2020 May 18:jiaa262. doi: 10.1093/infdis/jiaa262. Online ahead of print,ahmed.attia@ pharma.cu.edu.eg,The ggt::Tn mutant caused significantly less pathological damage compared with the WT.,N M Elhossieny 2020,2020,1 gene,Elhossieny-2020-Gamma-glutamyl transferase is,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16576,PHI:10510,UniProt,A0A505MF50,GenBank,TPS01751,,,MRSN7460,ggt,,,,,,,470,Acinetobacter baumannii,,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,gamma-glutamyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32421167,PubMed,10.1093/infdis/jiaa262,J Infect Dis. 2020 May 18:jiaa262. doi: 10.1093/infdis/jiaa262. Online ahead of print,ahmed.attia@ pharma.cu.edu.eg,The ggt::Tn mutant caused significantly less pathological damage compared with the WT.,N M Elhossieny 2020,2020,1 gene,Elhossieny-2020-Gamma-glutamyl transferase is,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16577,PHI:10511,UniProt,no data found,GenBank,,,,,SCRE1 (UV_2799),,,,,,,1159556,Ustilaginoidea virens,,P1,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,caryopsis,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,gene deletion: full; gene complementation,,,YVS,32087618,PubMed,10.1111/mpp.12894,Mol Plant Pathol. 2020 Apr;21(4):445-459. doi: 10.1111/mpp.12894. Epub 2020 Feb 22,wxs@cau.edu.cn,The scre1 knockout mutant was attenuated in U. virens virulence to rice.,N Zhang 2020,2020,1 gene,Zhang-2020-The essential effector SCRE1 in Ust,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16578,PHI:10511,UniProt,no data found,GenBank,,,,,SCRE1 (UV_2799 ),,SCRE1 1-179(45AAAAA49),,,,,1159556,Ustilaginoidea virens,,P1,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,caryopsis,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,functional test in host: purified protein,,,YVS,32087618,PubMed,10.1111/mpp.12894,Mol Plant Pathol. 2020 Apr;21(4):445-459. doi: 10.1111/mpp.12894. Epub 2020 Feb 22,wxs@cau.edu.cn,The scre1 knockout mutant was attenuated in U. virens virulence to rice.,N Zhang 2020,2020,1 gene,Zhang-2020-The essential effector SCRE1 in Ust,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16579,PHI:10511,UniProt,no data found,GenBank,,,,,SCRE1 (UV_2799 ),,SCRE1 1-179,,,,,1159556,Ustilaginoidea virens,,P1,bacterial blight,monocots,4530,Oryza sativa (related: rice),,,,caryopsis,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,functional test in host: purified protein,,,YVS,32087618,PubMed,10.1111/mpp.12894,Mol Plant Pathol. 2020 Apr;21(4):445-459. doi: 10.1111/mpp.12894. Epub 2020 Feb 22,wxs@cau.edu.cn,The scre1 knockout mutant was attenuated in U. virens virulence to rice.,N Zhang 2020,2020,1 gene,Zhang-2020-The essential effector SCRE1 in Ust,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16580,PHI:10511,UniProt,no data found,GenBank,,,,,SCRE1 (UV_2799 ),,,,,,,1159556,Ustilaginoidea virens,,P1,bacterial blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,functional test in host: transient expression,,,YVS,32087618,PubMed,10.1111/mpp.12894,Mol Plant Pathol. 2020 Apr;21(4):445-459. doi: 10.1111/mpp.12894. Epub 2020 Feb 22,wxs@cau.edu.cn,The scre1 knockout mutant was attenuated in U. virens virulence to rice.,N Zhang 2020,2020,1 gene,Zhang-2020-The essential effector SCRE1 in Ust,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16581,PHI:10511,UniProt,no data found,GenBank,,,,,SCRE1 (UV_2799 ),,SCRE1 45-70,,,,,1159556,Ustilaginoidea virens,,P1,bacterial blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,functional test in host: transient expression,,,YVS,32087618,PubMed,10.1111/mpp.12894,Mol Plant Pathol. 2020 Apr;21(4):445-459. doi: 10.1111/mpp.12894. Epub 2020 Feb 22,wxs@cau.edu.cn,The scre1 knockout mutant was attenuated in U. virens virulence to rice.,N Zhang 2020,2020,1 gene,Zhang-2020-The essential effector SCRE1 in Ust,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16582,PHI:10511,UniProt,no data found,GenBank,,,,,SCRE1 (UV_2799 ),,SCRE1 50-70 and SCRE1 45-65,,,,,1159556,Ustilaginoidea virens,,P1,bacterial blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,functional test in host: transient expression,,,YVS,32087618,PubMed,10.1111/mpp.12894,Mol Plant Pathol. 2020 Apr;21(4):445-459. doi: 10.1111/mpp.12894. Epub 2020 Feb 22,wxs@cau.edu.cn,The scre1 knockout mutant was attenuated in U. virens virulence to rice.,N Zhang 2020,2020,1 gene,Zhang-2020-The essential effector SCRE1 in Ust,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16583,PHI:10511,UniProt,no data found,GenBank,,,,,SCRE1 (UV_2799 ),,SCRE1 1-179(45AAAAA49),,,,,1159556,Ustilaginoidea virens,,P1,bacterial blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,functional test in host: transient expression,,,YVS,32087618,PubMed,10.1111/mpp.12894,Mol Plant Pathol. 2020 Apr;21(4):445-459. doi: 10.1111/mpp.12894. Epub 2020 Feb 22,wxs@cau.edu.cn,The scre1 knockout mutant was attenuated in U. virens virulence to rice.,N Zhang 2020,2020,1 gene,Zhang-2020-The essential effector SCRE1 in Ust,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16584,PHI:10511,UniProt,no data found,GenBank,,,,,SCRE1 (UV_2799 ),,SCRE1 45AAAAA49,,,,,1159556,Ustilaginoidea virens,,P1,bacterial blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,weaker defence response,functional test in host: transient expression,,,YVS,32087618,PubMed,10.1111/mpp.12894,Mol Plant Pathol. 2020 Apr;21(4):445-459. doi: 10.1111/mpp.12894. Epub 2020 Feb 22,wxs@cau.edu.cn,The scre1 knockout mutant was attenuated in U. virens virulence to rice.,N Zhang 2020,2020,1 gene,Zhang-2020-The essential effector SCRE1 in Ust,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16585,PHI:10512,UniProt,P09152,GenBank,CAA34303,,,TG1,narG,,,,,,PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,respiratory nitrate reductase 1 alpha chain,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16586,PHI:10513,UniProt,P11349,GenBank,CAA34304,,,TG1,narH,,,,,,PHI:10512; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,respiratory nitrate reductase 1 beta chain,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16587,PHI:10514,UniProt,P0AF26,GenBank,AAC74310,,,K-12,narJ,,,,,,PHI:10512; PHI:10513; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,nitrate reductase molybdenum cofactor assembly chaperone,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16588,PHI:10515,UniProt,P11350,GenBank,AAC74311,,,K-12,narI,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,respiratory nitrate reductase 1 gamma chain,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16589,PHI:10516,UniProt,P19319,GenBank,AAC74550,,,K-12,narZ,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,respiratory nitrate reductase 2 alpha chain,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16590,PHI:10517,UniProt,P19318,GenBank,AAC74549,,,K-12,narY,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,respiratory nitrate reductase 2 beta chain,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16591,PHI:10518,UniProt,P19317,GenBank,AAC74548,,,K-12,narW,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,probable nitrate reductase molybdenum cofactor assembly chaperone,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16592,PHI:10519,UniProt,P0AF32,GenBank,BAA15102,,,K-12,narV,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,respiratory nitrate reductase 2 gamma chain,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16593,PHI:10520,UniProt,P0AAL0,GenBank,AAC75268,,,K-12,napF,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,ferredoxin-type protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16594,PHI:10521,UniProt,P0A9I5,GenBank,AAC75267,,,K-12,napD,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10522; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,chaperone,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16595,PHI:10522,UniProt,P33937,GenBank,AAC75266,,,K-12,napA,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10523; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,periplasmic nitrate reductase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16596,PHI:10523,UniProt,P0AAL3,GenBank,AAC75265,,,K-12,napG,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10524; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,ferredoxin-type protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16597,PHI:10524,UniProt,P33934,GenBank,AAC75264,,,K-12,napH,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10525; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,ferredoxin-type protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16598,PHI:10525,UniProt,P0ABL3,GenBank,AAC75263,,,K-12,napB,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10526,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,"periplasmic nitrate reductase, electron transfer subunit",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16599,PHI:10526,UniProt,P0ABL5,GenBank,AAC75262,,,K-12,napC,,,,,,PHI:10512; PHI:10513; PHI:10514; PHI:10515; PHI:10516; PHI:10517; PHI:10518; PHI:10519; PHI:10520; PHI:10521; PHI:10522; PHI:10523; PHI:10524; PHI:10525,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,bladder; kidney,cytochrome c-type protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32082279,PubMed,10.3389/fmicb.2020.00026,Front Microbiol. 2020 Jan 31;11:26. doi: 10.3389/fmicb.2020.00026. eCollection 2020,agneta.richter.dahlfors@ki.se,Nitrate reduction was implicated as a bacterial fitness factor for colonization of the urinary tract by UPEC.,A J Martin-Rodriguez 2020,2020,15 genes,Martin-Rodriguez-2020-Nitrate Metabolism Modula,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16600,PHI:10527,UniProt,Q4WCU5,GenBank,EAL85793,,,Af293,GNA1,chromosome 6,,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (akuBKU80),aspergillosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,glucosamine-6-phosphate-N-acetyltransferase,,,,loss of pathogenicity,,,,,,,,,,no,Congo red; calcofluor white; sodium dodecyl sulphate; echinocandin; caspofungin,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulphate: CHEBI:8984; echinocandin: CHEBI:57248; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,32341126,PubMed,10.1074/jbc.RA120.012985,J Biol Chem. 2020 Apr 27:jbc.RA120.012985. doi: 10.1074/jbc.RA120.012985. Online ahead of print,dmfvanaalten@dundee.ac.uk,GNA1 deletion resulted in loss of fungal viability and disruption of the cell wall.,D E A Lockhart 2020,2020,1 gene,Lockhart-2020-Targeting a critical step in fun,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16601,PHI:10528,UniProt,A0A1D8PGE3,GenBank,AOW27228,,,SC5314,Rad23,chromosome 2,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,macrophage,nucleotide excision repair protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32075883,PubMed,10.1128/mSphere.00062-20,mSphere. 2020 Feb 19;5(1):e00062-20. doi: 10.1128/mSphere.00062-20,jinrong532@163.com,"The RAD23 deletion strain and overexpression strain both exhibited UV sensitivity, confirming the critical role of RAD23 in the nucleotide ex-cision repair pathway.",J Feng 2020,2020,2 genes,Feng-2020-Nucleotide Excision Repair Protein R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16602,PHI:10528,UniProt,A0A1D8PGE3,GenBank,AOW27228,,,SC5314,Rad23,chromosome 2,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,macrophage,nucleotide excision repair protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32075883,PubMed,10.1128/mSphere.00062-20,mSphere. 2020 Feb 19;5(1):e00062-20. doi: 10.1128/mSphere.00062-20,jinrong532@163.com,"The RAD23 deletion strain and overexpression strain both exhibited UV sensitivity, confirming the critical role of RAD23 in the nucleotide ex-cision repair pathway.",J Feng 2020,2020,2 genes,Feng-2020-Nucleotide Excision Repair Protein R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16603,PHI:10529,UniProt,Q5ADX0,GenBank,AOW28765,,,SC5314,Rad4,chromosome 3,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,macrophage,nucleotide excision repair protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32075883,PubMed,10.1128/mSphere.00062-20,mSphere. 2020 Feb 19;5(1):e00062-20. doi: 10.1128/mSphere.00062-20,jinrong532@163.com,"The RAD23 deletion strain and overexpression strain both exhibited UV sensitivity, confirming the critical role of RAD23 in the nucleotide ex-cision repair pathway.",J Feng 2020,2020,2 genes,Feng-2020-Nucleotide Excision Repair Protein R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16604,PHI:10530,UniProt,E9EUQ4,GenBank,EFZ01157,,,ARSEF 23,MrMao-1 (MAA_03753),,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,hemolymph,monoamine oxidase-1,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32271756,PubMed,10.1371/journal.pgen.1008675,PLoS Genet. 2020 Apr 9;16(4):e1008675. doi: 10.1371/journal.pgen.1008675. eCollection 2020 Apr,lkang@ioz.ac.cn,Tryptamine activated the aryl hydrocarbon receptor of locusts (LmAhR) that produced damaging effects by regulating reactive oxygen species production and suppressing the immune system of locusts.,X Tong 2020,2020,1 gene,Tong-2020-Tryptamine accumulation caused by de,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16605,PHI:10530,UniProt,E9EUQ4,GenBank,EFZ01157,,,ARSEF 23,MrMao-1 (MAA_03753),,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,monoamine oxidase-1,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32271756,PubMed,10.1371/journal.pgen.1008675,PLoS Genet. 2020 Apr 9;16(4):e1008675. doi: 10.1371/journal.pgen.1008675. eCollection 2020 Apr,lkang@ioz.ac.cn,Tryptamine activated the aryl hydrocarbon receptor of locusts (LmAhR) that produced damaging effects by regulating reactive oxygen species production and suppressing the immune system of locusts.,X Tong 2020,2020,1 gene,Tong-2020-Tryptamine accumulation caused by de,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16606,PHI:10530,UniProt,E9EUQ4,GenBank,EFZ01157,,,ARSEF 23,MrMao-1 (MAA_03753),,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,monoamine oxidase-1,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32271756,PubMed,10.1371/journal.pgen.1008675,PLoS Genet. 2020 Apr 9;16(4):e1008675. doi: 10.1371/journal.pgen.1008675. eCollection 2020 Apr,lkang@ioz.ac.cn,Tryptamine activated the aryl hydrocarbon receptor of locusts (LmAhR) that produced damaging effects by regulating reactive oxygen species production and suppressing the immune system of locusts.,X Tong 2020,2020,1 gene,Tong-2020-Tryptamine accumulation caused by de,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16607,PHI:10530,UniProt,E9EUQ4,GenBank,EFZ01157,,,ARSEF 23,MrMao-1 (MAA_03753),,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,aphids,7029,Acyrthosiphon pisum (related: pea aphid),,,,,monoamine oxidase-1,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32271756,PubMed,10.1371/journal.pgen.1008675,PLoS Genet. 2020 Apr 9;16(4):e1008675. doi: 10.1371/journal.pgen.1008675. eCollection 2020 Apr,lkang@ioz.ac.cn,Tryptamine activated the aryl hydrocarbon receptor of locusts (LmAhR) that produced damaging effects by regulating reactive oxygen species production and suppressing the immune system of locusts.,X Tong 2020,2020,1 gene,Tong-2020-Tryptamine accumulation caused by de,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16608,PHI:10530,UniProt,E9EUQ4,GenBank,EFZ01157,,,ARSEF 23,MrMao-1 (MAA_03753),,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,mosquitos,7159,Aedes aegypti (related: yellow fever mosquito),,,,,monoamine oxidase-1,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32271756,PubMed,10.1371/journal.pgen.1008675,PLoS Genet. 2020 Apr 9;16(4):e1008675. doi: 10.1371/journal.pgen.1008675. eCollection 2020 Apr,lkang@ioz.ac.cn,Tryptamine activated the aryl hydrocarbon receptor of locusts (LmAhR) that produced damaging effects by regulating reactive oxygen species production and suppressing the immune system of locusts.,X Tong 2020,2020,1 gene,Tong-2020-Tryptamine accumulation caused by de,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16609,PHI:10530,UniProt,E9EUQ4,GenBank,EFZ01157,,,ARSEF 23,MrMao-1 (MAA_03753),,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,roaches,6978,Periplaneta americana (related: American cockroach),,,,,monoamine oxidase-1,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32271756,PubMed,10.1371/journal.pgen.1008675,PLoS Genet. 2020 Apr 9;16(4):e1008675. doi: 10.1371/journal.pgen.1008675. eCollection 2020 Apr,lkang@ioz.ac.cn,Tryptamine activated the aryl hydrocarbon receptor of locusts (LmAhR) that produced damaging effects by regulating reactive oxygen species production and suppressing the immune system of locusts.,X Tong 2020,2020,1 gene,Tong-2020-Tryptamine accumulation caused by de,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16610,PHI:10531,UniProt,S3MJJ8,GenBank,EPF68055,,,SM,mexB,,,,,,,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,infection,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,efflux pump membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,catechol; coumarin; acetovanillone; ampicillin; chloramphenicol,catechol: CHEBI:18135; coumarin: CHEBI:28794; acetovanillone: CHEBI:2781; ampicillin: CHEBI:28971; chloramphenicol: CHEBI:17698,,,,,gene deletion: full,,,YVS,32296294,PubMed,10.5423/PPJ.OA.11.2019.0273,Plant Pathol J. 2020 Apr 1;36(2):148-156. doi: 10.5423/PPJ.OA.11.2019.0273,yuki@okayama-u.ac.jp,The swarming and swimming motilities were impaired in ΔmexF and ΔmexBΔmexF mutants.,Y Ichinose 2020,2020,3 genes,Ichinose-2020-Role of Two Sets of RND-Type Mul,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16611,PHI:10532,UniProt,A0A1U7ET34,GenBank,BAX00074,,,6605,mexF,,,,,,,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,infection,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,multidrug efflux RND transporter,,,,reduced virulence,,,,,,,,wild type,,no,catechol; coumarin; acetovanillone; ampicillin; chloramphenicol,catechol: CHEBI:18135; coumarin: CHEBI:28794; acetovanillone: CHEBI:2781; ampicillin: CHEBI:28971; chloramphenicol: CHEBI:17698,,,,,gene deletion: full,,,YVS,32296294,PubMed,10.5423/PPJ.OA.11.2019.0273,Plant Pathol J. 2020 Apr 1;36(2):148-156. doi: 10.5423/PPJ.OA.11.2019.0273,yuki@okayama-u.ac.jp,The swarming and swimming motilities were impaired in ΔmexF and ΔmexBΔmexF mutants.,Y Ichinose 2020,2020,3 genes,Ichinose-2020-Role of Two Sets of RND-Type Mul,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16612,PHI:10531,UniProt,S3MJJ8,GenBank,EPF68055,,,SM,mexB,,,,,,PHI:10532,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,infection,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,efflux pump membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,catechol; coumarin; acetovanillone; ampicillin; chloramphenicol,catechol: CHEBI:18135; coumarin: CHEBI:28794; acetovanillone: CHEBI:2781; ampicillin: CHEBI:28971; chloramphenicol: CHEBI:17698,,,,,gene deletion: full,,,YVS,32296294,PubMed,10.5423/PPJ.OA.11.2019.0273,Plant Pathol J. 2020 Apr 1;36(2):148-156. doi: 10.5423/PPJ.OA.11.2019.0273,yuki@okayama-u.ac.jp,The swarming and swimming motilities were impaired in ΔmexF and ΔmexBΔmexF mutants.,Y Ichinose 2020,2020,3 genes,Ichinose-2020-Role of Two Sets of RND-Type Mul,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16613,PHI:10532,UniProt,A0A1U7ET34,GenBank,BAX00074,,,6605,mexF,,,,,,PHI:10531,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,infection,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,multidrug efflux RND transporter,,,,reduced virulence,,,,,,,,wild type,,no,catechol; coumarin; acetovanillone; ampicillin; chloramphenicol,catechol: CHEBI:18135; coumarin: CHEBI:28794; acetovanillone: CHEBI:2781; ampicillin: CHEBI:28971; chloramphenicol: CHEBI:17698,,,,,gene deletion: full,,,YVS,32296294,PubMed,10.5423/PPJ.OA.11.2019.0273,Plant Pathol J. 2020 Apr 1;36(2):148-156. doi: 10.5423/PPJ.OA.11.2019.0273,yuki@okayama-u.ac.jp,The swarming and swimming motilities were impaired in ΔmexF and ΔmexBΔmexF mutants.,Y Ichinose 2020,2020,3 genes,Ichinose-2020-Role of Two Sets of RND-Type Mul,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16614,PHI:10533,UniProt,C5IJF6,GenBank,ACR46692,,,ATCC 11528,hrcC,,,,,,,317,Pseudomonas syringae,1189622,pv. tabaci strain 6605,infection,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,type 3 secretion system secretin,,,,unaffected pathogenicity,,,,,,,,wild type,,no,catechol; coumarin; acetovanillone; ampicillin; chloramphenicol,catechol: CHEBI:18135; coumarin: CHEBI:28794; acetovanillone: CHEBI:2781; ampicillin: CHEBI:28971; chloramphenicol: CHEBI:17698,,,,,gene deletion: full,,,YVS,32296294,PubMed,10.5423/PPJ.OA.11.2019.0273,Plant Pathol J. 2020 Apr 1;36(2):148-156. doi: 10.5423/PPJ.OA.11.2019.0273,yuki@okayama-u.ac.jp,The swarming and swimming motilities were impaired in ΔmexF and ΔmexBΔmexF mutants.,Y Ichinose 2020,2020,3 genes,Ichinose-2020-Role of Two Sets of RND-Type Mul,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16615,PHI:10534,UniProt,Q5HFT0,GenBank,AAW36728,,,COL,srrA,,,,,,PHI:10535,1280,Staphylococcus aureus,548470,MN8,infective endocarditis; sepsis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,aortic valve,transcriptional regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32354997,PubMed,10.1073/pnas.1921307117,Proc Natl Acad Sci U S A. 2020 May 19;117(20):10989-10999. doi: 10.1073/pnas.1921307117. Epub 2020 Apr 30,ernesto-fuentes@uiowa.edu,"SrrB cysteine disulfide bond was important for SrrAB function in vivo and, in its absence, repression of virulence by the SrrAB TCS was relieved.",N Tiwari 2020,2020,2 genes,Tiwari-2020-The SrrAB two-component system reg,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16616,PHI:10535,UniProt,Q5HFT1,GenBank,AAW36727,,,COL,srrB,,,,,,PHI:10534,1280,Staphylococcus aureus,548470,MN8,infective endocarditis; sepsis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,aortic valve,sensor histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32354997,PubMed,10.1073/pnas.1921307117,Proc Natl Acad Sci U S A. 2020 May 19;117(20):10989-10999. doi: 10.1073/pnas.1921307117. Epub 2020 Apr 30,ernesto-fuentes@uiowa.edu,"SrrB cysteine disulfide bond was important for SrrAB function in vivo and, in its absence, repression of virulence by the SrrAB TCS was relieved.",N Tiwari 2020,2020,2 genes,Tiwari-2020-The SrrAB two-component system reg,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16617,PHI:10534,UniProt,Q5HFT0,GenBank,AAW36728,,,COL,srrA,,,,,,PHI:10535,1280,Staphylococcus aureus,548470,MN8,infective endocarditis; sepsis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,aortic valve,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32354997,PubMed,10.1073/pnas.1921307117,Proc Natl Acad Sci U S A. 2020 May 19;117(20):10989-10999. doi: 10.1073/pnas.1921307117. Epub 2020 Apr 30,ernesto-fuentes@uiowa.edu,"SrrB cysteine disulfide bond was important for SrrAB function in vivo and, in its absence, repression of virulence by the SrrAB TCS was relieved.",N Tiwari 2020,2020,2 genes,Tiwari-2020-The SrrAB two-component system reg,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16618,PHI:10535,UniProt,Q5HFT1,GenBank,AAW36727,,,COL,srrB,,,,,,PHI:10534,1280,Staphylococcus aureus,548470,MN8,infective endocarditis; sepsis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,aortic valve,sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32354997,PubMed,10.1073/pnas.1921307117,Proc Natl Acad Sci U S A. 2020 May 19;117(20):10989-10999. doi: 10.1073/pnas.1921307117. Epub 2020 Apr 30,ernesto-fuentes@uiowa.edu,"SrrB cysteine disulfide bond was important for SrrAB function in vivo and, in its absence, repression of virulence by the SrrAB TCS was relieved.",N Tiwari 2020,2020,2 genes,Tiwari-2020-The SrrAB two-component system reg,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16619,PHI:10534,UniProt,Q5HFT0,GenBank,AAW36728,,,COL,srrA,,,,,,PHI:10535,1280,Staphylococcus aureus,548470,MN8,infective endocarditis; sepsis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,aortic valve,transcriptional regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32354997,PubMed,10.1073/pnas.1921307117,Proc Natl Acad Sci U S A. 2020 May 19;117(20):10989-10999. doi: 10.1073/pnas.1921307117. Epub 2020 Apr 30,ernesto-fuentes@uiowa.edu,"SrrB cysteine disulfide bond was important for SrrAB function in vivo and, in its absence, repression of virulence by the SrrAB TCS was relieved.",N Tiwari 2020,2020,2 genes,Tiwari-2020-The SrrAB two-component system reg,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16620,PHI:10535,UniProt,Q5HFT1,GenBank,AAW36727,,,COL,srrB,,srrB C501A overexpression,,,,PHI:10534,1280,Staphylococcus aureus,548470,MN8,infective endocarditis; sepsis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,aortic valve,sensor histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; altered gene expression / gene regulation: overexpression,,,YVS,32354997,PubMed,10.1073/pnas.1921307117,Proc Natl Acad Sci U S A. 2020 May 19;117(20):10989-10999. doi: 10.1073/pnas.1921307117. Epub 2020 Apr 30,ernesto-fuentes@uiowa.edu,"SrrB cysteine disulfide bond was important for SrrAB function in vivo and, in its absence, repression of virulence by the SrrAB TCS was relieved.",N Tiwari 2020,2020,2 genes,Tiwari-2020-The SrrAB two-component system reg,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16621,PHI:10536,UniProt,D2TR63,GenBank,CBG87650,,,ICC168,artP,,,,,,,67825,Citrobacter rodentium,,DBS770,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,intestine,"arginine ABC transporter, ATP-binding protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32409599,PubMed,10.1073/pnas.1919683117,Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12387-12393. doi: 10.1073/pnas.1919683117. Epub 2020 May 14,vanessa.sperandio@utsouthwestern.edu,"The ΔartP strain of DBS770 did not colonize the murine intestine, and consequently, mice infected with this mutant survived infection.",Z Menezes-Garcia 2020,2020,2 genes,Menezes-Garcia-2020-l-Arginine sensing regulat,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16622,PHI:10537,UniProt,D2TNF0,GenBank,CBG91281,,,ICC168,argR,,,,,,,67825,Citrobacter rodentium,,DBS770,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,cecum; colon,arginine repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32409599,PubMed,10.1073/pnas.1919683117,Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12387-12393. doi: 10.1073/pnas.1919683117. Epub 2020 May 14,vanessa.sperandio@utsouthwestern.edu,The ΔargR mutant presented decreased inflammation in the colon and delayed mortality.,Z Menezes-Garcia 2020,2020,2 genes,Menezes-Garcia-2020-l-Arginine sensing regulat,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16623,PHI:10538,UniProt,P54292,GenBank,AAC44036,,,PAO1,RhlR,chromosome 1,,,,,,287,Pseudomonas aeruginosa,652611,PA14,bacterial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,regulatory protein RhlR,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32265891,PubMed,10.3389/fmicb.2020.00471,Front Microbiol. 2020 Mar 20;11:471. doi: 10.3389/fmicb.2020.00471. eCollection 2020,lisa.kirchhoff@uk-essen.de,"Both biofilm and planktonic culture filtrate of Pa increased the killing of Ed-infected larvae, whereas, planktonic culture filtrates of both QS-deficient mutants were comparable to those associated with the WT.",L Kirchhoff 2020,2020,2 genes,Kirchhoff-2020-Phenotypical Characteristics of,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16624,PHI:10539,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,bacterial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,transcriptional activator protein LasR,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32265891,PubMed,10.3389/fmicb.2020.00471,Front Microbiol. 2020 Mar 20;11:471. doi: 10.3389/fmicb.2020.00471. eCollection 2020,lisa.kirchhoff@uk-essen.de,"Both biofilm and planktonic culture filtrate of Pa increased the killing of Ed-infected larvae, whereas, planktonic culture filtrates of both QS-deficient mutants were comparable to those associated with the WT.",L Kirchhoff 2020,2020,2 genes,Kirchhoff-2020-Phenotypical Characteristics of,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16625,PHI:10540,UniProt,A0A2K8W3I0,GenBank,AUC44067,,,RNS 08.23.3.1.A,lon,,,,,,,1089444,Dickeya solani,1225786,IPO 2222,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),cv. Vineta,,,tuber,protease,,,,reduced virulence,,,,,,,,wild type,,no,sucrose; NaCl; H2O2,sucrose: CHEBI:17992; NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32456249,PubMed,10.3390/ijms21103687,Int J Mol Sci. 2020 May 23;21(10):3687. doi: 10.3390/ijms21103687,donata.figaj@ug.edu.pl,"No difference was observed in the degree of maceration of the tuber or leaf tissues between the WT and mutant strains, hence, the observed delay in the potato plant infection process was most probably due to reduced motility of the Δlon strain.",D Figaj 2020,2020,1 gene,Figaj-2020-Lon Protease Is Important for Growt,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16626,PHI:10541,UniProt,O53168,GenBank,CCP44237,,,H37Rv,RipA (rv1477),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,"D,L-endopeptidase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32127458,PubMed,10.1128/mBio.03315-19,mBio. 2020 Mar 3;11(2):e03315-19. doi: 10.1128/mBio.03315-19,sae2004@med.cornell.edu,Depletion of RipA prevented M. tuberculosis from replicating in macrophages and led to dramatic killing of the bacteria in mice.,C Healy 2020,2020,2 genes,Healy-2020-Peptidoglycan Hydrolases RipA and A,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16627,PHI:10542,UniProt,I6Y4D2,GenBank,CCP46543,,,H37Rv,Ami1 (Rv3717),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,N-acetylmuramyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32127458,PubMed,10.1128/mBio.03315-19,mBio. 2020 Mar 3;11(2):e03315-19. doi: 10.1128/mBio.03315-19,sae2004@med.cornell.edu,Ami1 was dispensable for cell division in M. tuberculosis in vitro yet contributed to the bacterium's ability to persist during chronic infection in mice.,C Healy 2020,2020,2 genes,Healy-2020-Peptidoglycan Hydrolases RipA and A,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16628,PHI:10542,UniProt,I6Y4D2,GenBank,CCP46543,,,H37Rv,Ami1 (Rv3717),,(Δami1::ami1E200A),,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,N-acetylmuramyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32127458,PubMed,10.1128/mBio.03315-19,mBio. 2020 Mar 3;11(2):e03315-19. doi: 10.1128/mBio.03315-19,sae2004@med.cornell.edu,Ami1 was dispensable for cell division in M. tuberculosis in vitro yet contributed to the bacterium's ability to persist during chronic infection in mice.,C Healy 2020,2020,2 genes,Healy-2020-Peptidoglycan Hydrolases RipA and A,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16629,PHI:10541,UniProt,O53168,GenBank,CCP44237,,,H37Rv,RipA (rv1477),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,"D,L-endopeptidase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32127458,PubMed,10.1128/mBio.03315-19,mBio. 2020 Mar 3;11(2):e03315-19. doi: 10.1128/mBio.03315-19,sae2004@med.cornell.edu,Depletion of RipA prevented M. tuberculosis from replicating in macrophages and led to dramatic killing of the bacteria in mice.,C Healy 2020,2020,2 genes,Healy-2020-Peptidoglycan Hydrolases RipA and A,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16630,PHI:10542,UniProt,I6Y4D2,GenBank,CCP46543,,,H37Rv,Ami1 (Rv3717),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,N-acetylmuramyl-L-alanine amidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32127458,PubMed,10.1128/mBio.03315-19,mBio. 2020 Mar 3;11(2):e03315-19. doi: 10.1128/mBio.03315-19,sae2004@med.cornell.edu,No attenuation of the M. tuberculosis Δami1 mutant was observed during macrophage infection.,C Healy 2020,2020,2 genes,Healy-2020-Peptidoglycan Hydrolases RipA and A,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16631,PHI:10543,UniProt,J7MBE3,GenBank,BAM31097,,,M1 476,spd,chromosome 1,,,,,,1314,Streptococcus pyogenes,,ATCC 11434,acute glomerulonephritis; pharyngitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; lymph node; spleen; liver; blood,deoxyribonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32094510,PubMed,10.1038/s41598-020-60306-w,Sci Rep. 2020 Feb 24;10(1):3251. doi: 10.1038/s41598-020-60306-w,motanaka-tky@umin.ac.jp,"Mice infected with deoxyribonuclease knockout GAS mutants (Δspd, ΔendA, and ΔsdaD2) survived signifcantly better than those infected with wild-type GAS.",M Tanaka 2020,2020,3 genes,Tanaka-2020-Group A Streptococcus establishes,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16632,PHI:10544,UniProt,Q1JMI4,GenBank,ABF31828,,,MGAS9429,endA,,,,,,,1314,Streptococcus pyogenes,,ATCC 11434,acute glomerulonephritis; pharyngitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; lymph node; spleen; liver; blood,deoxyribonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32094510,PubMed,10.1038/s41598-020-60306-w,Sci Rep. 2020 Feb 24;10(1):3251. doi: 10.1038/s41598-020-60306-w,motanaka-tky@umin.ac.jp,"Mice infected with deoxyribonuclease knockout GAS mutants (Δspd, ΔendA, and ΔsdaD2) survived signifcantly better than those infected with wild-type GAS.",M Tanaka 2020,2020,3 genes,Tanaka-2020-Group A Streptococcus establishes,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16633,PHI:10545,UniProt,J7MAX3,GenBank,BAM30812,,,M1 476,sdaD2,chromosome 1,,,,,,1314,Streptococcus pyogenes,,ATCC 11434,acute glomerulonephritis; pharyngitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; lymph node; spleen; liver; blood,deoxyribonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32094510,PubMed,10.1038/s41598-020-60306-w,Sci Rep. 2020 Feb 24;10(1):3251. doi: 10.1038/s41598-020-60306-w,motanaka-tky@umin.ac.jp,"Mice infected with deoxyribonuclease knockout GAS mutants (Δspd, ΔendA, and ΔsdaD2) survived signifcantly better than those infected with wild-type GAS.",M Tanaka 2020,2020,3 genes,Tanaka-2020-Group A Streptococcus establishes,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16634,PHI:10543,UniProt,J7MBE3,GenBank,BAM31097,,,M1 476,spd,,,,,,,1314,Streptococcus pyogenes,,ATCC 11434,acute glomerulonephritis; pharyngitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,deoxyribonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32094510,PubMed,10.1038/s41598-020-60306-w,Sci Rep. 2020 Feb 24;10(1):3251. doi: 10.1038/s41598-020-60306-w,motanaka-tky@umin.ac.jp,"Mice infected with deoxyribonuclease knockout GAS mutants (Δspd, ΔendA, and ΔsdaD2) survived signifcantly better than those infected with wild-type GAS.",M Tanaka 2020,2020,3 genes,Tanaka-2020-Group A Streptococcus establishes,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16635,PHI:10544,UniProt,Q1JMI4,GenBank,ABF31828,,,MGAS9429,endA,,,,,,,1314,Streptococcus pyogenes,,ATCC 11434,acute glomerulonephritis; pharyngitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,deoxyribonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32094510,PubMed,10.1038/s41598-020-60306-w,Sci Rep. 2020 Feb 24;10(1):3251. doi: 10.1038/s41598-020-60306-w,motanaka-tky@umin.ac.jp,"Mice infected with deoxyribonuclease knockout GAS mutants (Δspd, ΔendA, and ΔsdaD2) survived signifcantly better than those infected with wild-type GAS.",M Tanaka 2020,2020,3 genes,Tanaka-2020-Group A Streptococcus establishes,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16636,PHI:10545,UniProt,J7MAX3,GenBank,BAM30812,,,M1 476,sdaD2,,,,,,,1314,Streptococcus pyogenes,,ATCC 11434,acute glomerulonephritis; pharyngitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,deoxyribonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32094510,PubMed,10.1038/s41598-020-60306-w,Sci Rep. 2020 Feb 24;10(1):3251. doi: 10.1038/s41598-020-60306-w,motanaka-tky@umin.ac.jp,"Mice infected with deoxyribonuclease knockout GAS mutants (Δspd, ΔendA, and ΔsdaD2) survived signifcantly better than those infected with wild-type GAS.",M Tanaka 2020,2020,3 genes,Tanaka-2020-Group A Streptococcus establishes,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16637,PHI:10543,UniProt,J7MBE3,GenBank,BAM31097,,,M1 476,spd,,,,,,,1314,Streptococcus pyogenes,,ATCC 11434,acute glomerulonephritis; pharyngitis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,deoxyribonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32094510,PubMed,10.1038/s41598-020-60306-w,Sci Rep. 2020 Feb 24;10(1):3251. doi: 10.1038/s41598-020-60306-w,motanaka-tky@umin.ac.jp,"Mice infected with deoxyribonuclease knockout GAS mutants (Δspd, ΔendA, and ΔsdaD2) survived signifcantly better than those infected with wild-type GAS.",M Tanaka 2020,2020,3 genes,Tanaka-2020-Group A Streptococcus establishes,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16638,PHI:10544,UniProt,Q1JMI4,GenBank,ABF31828,,,MGAS9429,endA,,,,,,,1314,Streptococcus pyogenes,,ATCC 11434,acute glomerulonephritis; pharyngitis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,deoxyribonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32094510,PubMed,10.1038/s41598-020-60306-w,Sci Rep. 2020 Feb 24;10(1):3251. doi: 10.1038/s41598-020-60306-w,motanaka-tky@umin.ac.jp,"Mice infected with deoxyribonuclease knockout GAS mutants (Δspd, ΔendA, and ΔsdaD2) survived signifcantly better than those infected with wild-type GAS.",M Tanaka 2020,2020,3 genes,Tanaka-2020-Group A Streptococcus establishes,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16639,PHI:10545,UniProt,J7MAX3,GenBank,BAM30812,,,M1 476,sdaD2,,,,,,,1314,Streptococcus pyogenes,,ATCC 11434,acute glomerulonephritis; pharyngitis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,deoxyribonuclease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32094510,PubMed,10.1038/s41598-020-60306-w,Sci Rep. 2020 Feb 24;10(1):3251. doi: 10.1038/s41598-020-60306-w,motanaka-tky@umin.ac.jp,"Mice infected with deoxyribonuclease knockout GAS mutants (Δspd, ΔendA, and ΔsdaD2) survived signifcantly better than those infected with wild-type GAS.",M Tanaka 2020,2020,3 genes,Tanaka-2020-Group A Streptococcus establishes,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16640,PHI:10546,UniProt,A0A168D336,GenBank,ANC22315,,,HN001,plcR (WR52_27275),,,,,,,1396,Bacillus cereus,,HN001,diarrhea; nausea; vomiting,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,helix-turn-helix transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32507026,PubMed,10.1080/21505594.2020.1773077,Virulence. 2020 Dec;11(1):769-780. doi: 10.1080/21505594.2020.1773077,jiangyq@bmi.ac.cn,Flagellin knockout decreases the lethality of B. cereus in a murine infection model.,S Gao 2020,2020,2 genes,Gao-2020-The interaction between flagellin and,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16641,PHI:10547,UniProt,A0A160HAV3,GenBank,ANC18764,,,HN001,fla (WR52_08290),,,,,,,1396,Bacillus cereus,,HN001,diarrhea; nausea; vomiting,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32507026,PubMed,10.1080/21505594.2020.1773077,Virulence. 2020 Dec;11(1):769-780. doi: 10.1080/21505594.2020.1773077,jiangyq@bmi.ac.cn,Flagellin knockout decreases the lethality of B. cereus in a murine infection model.,S Gao 2020,2020,2 genes,Gao-2020-The interaction between flagellin and,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16642,PHI:10547,UniProt,A0A160HAV3,GenBank,ANC18764,,,HN001,fla (WR52_08290),,,,,,,1396,Bacillus cereus,,HN001,diarrhea; nausea; vomiting,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32507026,PubMed,10.1080/21505594.2020.1773077,Virulence. 2020 Dec;11(1):769-780. doi: 10.1080/21505594.2020.1773077,jiangyq@bmi.ac.cn,Host gene alteration data available for Gb3 (host-cell-surface-localized glycosphingolipid).,S Gao 2020,2020,2 genes,Gao-2020-The interaction between flagellin and,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16643,PHI:10548,UniProt,A0A0D6I2I2,GenBank,AKH09371,,,YU39,spoT,,SpoT protein that lacks the C-terminal regulatory elements,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,liver; spleen,(P)ppGpp synthetase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,32098823,PubMed,10.1128/mBio.03397-19,mBio. 2020 Feb 25;11(1):e03397-19. doi: 10.1128/mBio.03397-19,Andres.Vazquez-Torres@cuanschutz.edu,SpoT serves a unique function in the adaptation of Salmonella to the intracellular environment of host phagocytes that cannot be compensated by the presence of a functional RelA.,L F Fitzsimmons 2020,2020,2 genes,Fitzsimmons-2020-SpoT Induces Intracellular Sa,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16644,PHI:10548,UniProt,A0A0D6I2I2,GenBank,AKH09371,,,YU39,spoT,,SpoT protein that lacks the C-terminal regulatory elements,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,(P)ppGpp synthetase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,32098823,PubMed,10.1128/mBio.03397-19,mBio. 2020 Feb 25;11(1):e03397-19. doi: 10.1128/mBio.03397-19,Andres.Vazquez-Torres@cuanschutz.edu,SpoT serves a unique function in the adaptation of Salmonella to the intracellular environment of host phagocytes that cannot be compensated by the presence of a functional RelA.,L F Fitzsimmons 2020,2020,2 genes,Fitzsimmons-2020-SpoT Induces Intracellular Sa,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16645,PHI:10548,UniProt,A0A0D6I2I2,GenBank,AKH09371,,,YU39,spoT,,SpoT protein that lacks the C-terminal regulatory elements,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,(P)ppGpp synthetase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,32098823,PubMed,10.1128/mBio.03397-19,mBio. 2020 Feb 25;11(1):e03397-19. doi: 10.1128/mBio.03397-19,Andres.Vazquez-Torres@cuanschutz.edu,SpoT serves a unique function in the adaptation of Salmonella to the intracellular environment of host phagocytes that cannot be compensated by the presence of a functional RelA.,L F Fitzsimmons 2020,2020,2 genes,Fitzsimmons-2020-SpoT Induces Intracellular Sa,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16646,PHI:10549,UniProt,Q8ZME2,GenBank,AAL21836,,,LT2,relA,,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,(P)ppGpp synthetase I,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,32098823,PubMed,10.1128/mBio.03397-19,mBio. 2020 Feb 25;11(1):e03397-19. doi: 10.1128/mBio.03397-19,Andres.Vazquez-Torres@cuanschutz.edu,SpoT serves a unique function in the adaptation of Salmonella to the intracellular environment of host phagocytes that cannot be compensated by the presence of a functional RelA.,L F Fitzsimmons 2020,2020,2 genes,Fitzsimmons-2020-SpoT Induces Intracellular Sa,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16647,PHI:10549,UniProt,Q8ZME2,GenBank,AAL21836,,,LT2,relA,,,,,,PHI:10548,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,(P)ppGpp synthetase I,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,32098823,PubMed,10.1128/mBio.03397-19,mBio. 2020 Feb 25;11(1):e03397-19. doi: 10.1128/mBio.03397-19,Andres.Vazquez-Torres@cuanschutz.edu,SpoT serves a unique function in the adaptation of Salmonella to the intracellular environment of host phagocytes that cannot be compensated by the presence of a functional RelA.,L F Fitzsimmons 2020,2020,2 genes,Fitzsimmons-2020-SpoT Induces Intracellular Sa,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16648,PHI:10548,UniProt,A0A0D6I2I2,GenBank,AKH09371,,,YU39,spoT,,,,,,PHI:10549,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,(P)ppGpp synthetase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,32098823,PubMed,10.1128/mBio.03397-19,mBio. 2020 Feb 25;11(1):e03397-19. doi: 10.1128/mBio.03397-19,Andres.Vazquez-Torres@cuanschutz.edu,SpoT serves a unique function in the adaptation of Salmonella to the intracellular environment of host phagocytes that cannot be compensated by the presence of a functional RelA.,L F Fitzsimmons 2020,2020,2 genes,Fitzsimmons-2020-SpoT Induces Intracellular Sa,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16649,PHI:10550,UniProt,I1RUP1,GenBank,CEF83458,,,PH-1,FgWC1 (FGSG_07941),chromosome 4,,,,,,282267,Fusarium asiaticum,,EXAP-08,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68,,,leaf,blue light receptor white collar complex protein,,,carotenoid biosynthesis,reduced virulence,,,,,,,reduced; aberrant,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32150839,PubMed,10.3390/microorganisms8030365,Microorganisms. 2020 Mar 5;8(3):365. doi: 10.3390/microorganisms8030365,lxu@bio.ecnu.edu.cn,"The two mutants showed similar defects in light-induced carotenoid biosynthesis, UV-C resistance, sexual fruiting body development.",Y Tang 2020,2020,2 genes,Tang-2020-The Photoreceptor Components FaWC1 a,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16650,PHI:10551,UniProt,I1RB11,GenBank,CEF72699,,,PH-1,FgWC2 (FGSG_00710),chromosome 1,,,,,,282267,Fusarium asiaticum,,EXAP-08,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68,,,leaf,blue light receptor white collar complex protein,,,carotenoid biosynthesis,unaffected pathogenicity,,,,,,,reduced; aberrant,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32150839,PubMed,10.3390/microorganisms8030365,Microorganisms. 2020 Mar 5;8(3):365. doi: 10.3390/microorganisms8030365,lxu@bio.ecnu.edu.cn,"The two mutants showed similar defects in light-induced carotenoid biosynthesis, UV-C resistance, sexual fruiting body development.",Y Tang 2020,2020,2 genes,Tang-2020-The Photoreceptor Components FaWC1 a,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16651,PHI:10552,UniProt,W8U6D4,GenBank,AUS75592,,,MRSA107,purR,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,purine biosynthesis regulator,,,purine biosynthesis,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32094249,PubMed,10.1128/IAI.00104-20,Infect Immun. 2020 Apr 20;88(5):e00104-20. doi: 10.1128/IAI.00104-20. Print 2020 Apr 20,deh@uwo.ca,Purine biosynthesis mutants demonstrated decreased replication in epithelial cells.,M I Goncheva 2020,2020,2 genes,Goncheva-2020-De Novo Purine Biosynthesis Is R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16652,PHI:10552,UniProt,W8U6D4,GenBank,AUS75592,,,MRSA107,purR,,,,,,PHI:10553,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,purine biosynthesis regulator,,,purine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32094249,PubMed,10.1128/IAI.00104-20,Infect Immun. 2020 Apr 20;88(5):e00104-20. doi: 10.1128/IAI.00104-20. Print 2020 Apr 20,deh@uwo.ca,Purine biosynthesis mutants demonstrated decreased replication in epithelial cells.,M I Goncheva 2020,2020,2 genes,Goncheva-2020-De Novo Purine Biosynthesis Is R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16653,PHI:10553,UniProt,Q6GAE8,GenBank,CAG42775,,,MSSA476,purK,,,,,,PHI:10552,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,purine biosynthesis regulator,,,phosphoribosylaminoimidazole carboxylase ATPase subunit,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32094249,PubMed,10.1128/IAI.00104-20,Infect Immun. 2020 Apr 20;88(5):e00104-20. doi: 10.1128/IAI.00104-20. Print 2020 Apr 20,deh@uwo.ca,Purine biosynthesis mutants demonstrated decreased replication in epithelial cells.,M I Goncheva 2020,2020,2 genes,Goncheva-2020-De Novo Purine Biosynthesis Is R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16654,PHI:10552,UniProt,W8U6D4,GenBank,AUS75592,,,MRSA107,purR,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; heart,purine biosynthesis regulator,,,purine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32094249,PubMed,10.1128/IAI.00104-20,Infect Immun. 2020 Apr 20;88(5):e00104-20. doi: 10.1128/IAI.00104-20. Print 2020 Apr 20,deh@uwo.ca,The purK mutation in the ΔpurR strain converted what was a hypervirulent purR mutant strain into an attenuated strain.,M I Goncheva 2020,2020,2 genes,Goncheva-2020-De Novo Purine Biosynthesis Is R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16655,PHI:10552,UniProt,W8U6D4,GenBank,AUS75592,,,MRSA107,purR,,,,,,PHI:10553,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; heart,purine biosynthesis regulator,,,purine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32094249,PubMed,10.1128/IAI.00104-20,Infect Immun. 2020 Apr 20;88(5):e00104-20. doi: 10.1128/IAI.00104-20. Print 2020 Apr 20,deh@uwo.ca,The purK mutation in the ΔpurR strain converted what was a hypervirulent purR mutant strain into an attenuated strain.,M I Goncheva 2020,2020,2 genes,Goncheva-2020-De Novo Purine Biosynthesis Is R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16656,PHI:10553,UniProt,Q6GAE8,GenBank,CAG42775,,,MSSA476,purK,,,,,,PHI:10552,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; heart,purine biosynthesis regulator,,,phosphoribosylaminoimidazole carboxylase ATPase subunit,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32094249,PubMed,10.1128/IAI.00104-20,Infect Immun. 2020 Apr 20;88(5):e00104-20. doi: 10.1128/IAI.00104-20. Print 2020 Apr 20,deh@uwo.ca,The purK mutation in the ΔpurR strain converted what was a hypervirulent purR mutant strain into an attenuated strain.,M I Goncheva 2020,2020,2 genes,Goncheva-2020-De Novo Purine Biosynthesis Is R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16657,PHI:10552,UniProt,W8U6D4,GenBank,AUS75592,,,MRSA107,purR,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,purine biosynthesis regulator,,,purine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32094249,PubMed,10.1128/IAI.00104-20,Infect Immun. 2020 Apr 20;88(5):e00104-20. doi: 10.1128/IAI.00104-20. Print 2020 Apr 20,deh@uwo.ca,De novo purine biosynthesis was required for S. aureus replication in macrophages.,M I Goncheva 2020,2020,2 genes,Goncheva-2020-De Novo Purine Biosynthesis Is R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16658,PHI:10552,UniProt,W8U6D4,GenBank,AUS75592,,,MRSA107,purR,,,,,,PHI:10553,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,purine biosynthesis regulator,,,purine biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32094249,PubMed,10.1128/IAI.00104-20,Infect Immun. 2020 Apr 20;88(5):e00104-20. doi: 10.1128/IAI.00104-20. Print 2020 Apr 20,deh@uwo.ca,De novo purine biosynthesis was required for S. aureus replication in macrophages.,M I Goncheva 2020,2020,2 genes,Goncheva-2020-De Novo Purine Biosynthesis Is R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16659,PHI:10553,UniProt,Q6GAE8,GenBank,CAG42775,,,MSSA476,purK,,,,,,PHI:10552,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,purine biosynthesis regulator,,,phosphoribosylaminoimidazole carboxylase ATPase subunit,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32094249,PubMed,10.1128/IAI.00104-20,Infect Immun. 2020 Apr 20;88(5):e00104-20. doi: 10.1128/IAI.00104-20. Print 2020 Apr 20,deh@uwo.ca,De novo purine biosynthesis was required for S. aureus replication in macrophages.,M I Goncheva 2020,2020,2 genes,Goncheva-2020-De Novo Purine Biosynthesis Is R,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16660,PHI:10554,UniProt,P29485,GenBank,CAA45453,,,"ssp. classical 01, Z17561",TcpP,,TcpP C58S,,,,,666,Vibrio cholerae,,El Tor C6706,diarrhea; cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,small intestine,toxin coregulated pilus biosynthesis protein P,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32117142,PubMed,10.3389/fmicb.2020.00118,Front Microbiol. 2020 Feb 6;11:118. doi: 10.3389/fmicb.2020.00118. eCollection 2020,yangmh@zafu.edu.cn,C58 of TcpP is indispensable for TcpP function and is essential for V. cholerae virulence factor production and pathogenesis.,M Shi 2020,2020,1 gene,Shi-2020-The 58th Cysteine of TcpP Is Essentia,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16661,PHI:10554,UniProt,P29485,GenBank,CAA45453,,,"ssp. classical 01, Z17561",TcpP,,TcpP C1951/124S,,,,,666,Vibrio cholerae,,El Tor C6706,diarrhea; cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,small intestine,toxin coregulated pilus biosynthesis protein P,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32117142,PubMed,10.3389/fmicb.2020.00118,Front Microbiol. 2020 Feb 6;11:118. doi: 10.3389/fmicb.2020.00118. eCollection 2020,yangmh@zafu.edu.cn,C58 of TcpP is indispensable for TcpP function and is essential for V. cholerae virulence factor production and pathogenesis.,M Shi 2020,2020,1 gene,Shi-2020-The 58th Cysteine of TcpP Is Essentia,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16662,PHI:10556,UniProt,A0A5P8AM17,GenBank,QFN66992,,,Xss-V2-18,tal2,,,,,,,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16663,PHI:10557,UniProt,A0A5P8AM20,GenBank,QFN66993,,,Xss-V2-18,tal3,,,,,,,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16664,PHI:10556,UniProt,A0A5P8AM17,GenBank,QFN66992,,,Xss-V2-18,tal2,,,,,,PHI:10558,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16665,PHI:10558,UniProt,A0A5P8AM02,GenBank,QFN66994,,,Xss-V2-18,tal4,,,,,,PHI:10556,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16666,PHI:10556,UniProt,A0A5P8AM17,GenBank,QFN66992,,,Xss-V2-18,tal2,,,,,,PHI:10558; PHI:10559; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16667,PHI:10558,UniProt,A0A5P8AM02,GenBank,QFN66994,,,Xss-V2-18,tal4,,,,,,PHI:10556; PHI:10559; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16668,PHI:10559,UniProt,A0A5P8ALZ8,GenBank,QFN66995,,,Xss-V2-18,tal5,,,,,,PHI:10556; PHI:10558; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16669,PHI:10560,UniProt,A0A5P8AM41,GenBank,QFN66996,,,Xss-V2-18,tal6,,,,,,PHI:10556; PHI:10558; PHI:10559,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16670,PHI:10556,UniProt,A0A5P8AM17,GenBank,QFN66992,,,Xss-V2-18,tal2,,,,,,PHI:10557; PHI:10558; PHI:10559; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16671,PHI:10557,UniProt,A0A5P8AM20,GenBank,QFN66993,,,Xss-V2-18,tal3,,,,,,PHI:10556; PHI:10558; PHI:10559; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16672,PHI:10558,UniProt,A0A5P8AM02,GenBank,QFN66994,,,Xss-V2-18,tal4,,,,,,PHI:10556; PHI:10557; PHI:10559; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16673,PHI:10559,UniProt,A0A5P8ALZ8,GenBank,QFN66995,,,Xss-V2-18,tal5,,,,,,PHI:10556; PHI:10557; PHI:10558; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16674,PHI:10560,UniProt,A0A5P8AM41,GenBank,QFN66996,,,Xss-V2-18,tal6,,,,,,PHI:10556; PHI:10557; PHI:10558; PHI:10559,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16675,PHI:10555,UniProt,A0A5P8APB0,GenBank,QFN66991,,,Xss-V2-18,tal1,,,,,,PHI:10556; PHI:10557; PHI:10558; PHI:10559; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16676,PHI:10556,UniProt,A0A5P8AM17,GenBank,QFN66992,,,Xss-V2-18,tal2,,,,,,PHI:10555; PHI:10557; PHI:10558; PHI:10559; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16677,PHI:10557,UniProt,A0A5P8AM20,GenBank,QFN66993,,,Xss-V2-18,tal3,,,,,,PHI:10555; PHI:10556; PHI:10558; PHI:10559; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16678,PHI:10558,UniProt,A0A5P8AM02,GenBank,QFN66994,,,Xss-V2-18,tal4,,,,,,PHI:10555; PHI:10556; PHI:10557; PHI:10559; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16679,PHI:10559,UniProt,A0A5P8ALZ8,GenBank,QFN66995,,,Xss-V2-18,tal5,,,,,,PHI:10555; PHI:10556; PHI:10557; PHI:10558; PHI:10560,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16680,PHI:10560,UniProt,A0A5P8AM41,GenBank,QFN66996,,,Xss-V2-18,tal6,,,,,,PHI:10555; PHI:10556; PHI:10557; PHI:10558; PHI:10559,346,Xanthomonas citri,,pv. malvacearum strain Xss-V2-18,bacterial blight (cotton),eudicots,3635,Gossypium hirsutum (related: cotton),cv. TM-1,,,leaf,TAL-effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32293266,PubMed,10.1186/s12866-020-01783-x,BMC Microbiol. 2020 Apr 15;20(1):91. doi: 10.1186/s12866-020-01783-x,gyouchen@sjtu.edu.cn,Tal2 was a major pathogenicity factor in Xcm strain Xss-V2–18 that contributed significantly in BBC.,F Haq 2020,2020,6 genes,Haq-2020-Identification of a virulence tal gen,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16681,PHI:10561,UniProt,A0A385EXL2,GenBank,AXQ91222,,,WM99c,pstS,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,phosphate-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32324853,PubMed,10.1093/infdis/jiaa201,J Infect Dis. 2020 Apr 23:jiaa201. doi: 10.1093/infdis/jiaa201. Online ahead of print,ysmani-ibis@us.es,PstS loss reduced motility and biofilm-forming ability of A. baumannii.,M L Gil-Marques 2020,2020,1 gene,Gil-Marqués-2020-Role of PstS on the pathogene,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16682,PHI:10561,UniProt,A0A385EXL2,GenBank,AXQ91222,,,WM99c,pstS,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,phosphate-binding protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32324853,PubMed,10.1093/infdis/jiaa201,J Infect Dis. 2020 Apr 23:jiaa201. doi: 10.1093/infdis/jiaa201. Online ahead of print,ysmani-ibis@us.es,PstS loss reduced motility and biofilm-forming ability of A. baumannii.,M L Gil-Marques 2020,2020,1 gene,Gil-Marqués-2020-Role of PstS on the pathogene,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16683,PHI:10561,UniProt,A0A385EXL2,GenBank,AXQ91222,,,WM99c,pstS,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; kidney,phosphate-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32324853,PubMed,10.1093/infdis/jiaa201,J Infect Dis. 2020 Apr 23:jiaa201. doi: 10.1093/infdis/jiaa201. Online ahead of print,ysmani-ibis@us.es,PstS loss reduced motility and biofilm-forming ability of A. baumannii.,M L Gil-Marques 2020,2020,1 gene,Gil-Marqués-2020-Role of PstS on the pathogene,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16684,PHI:10562,UniProt,Q0P8D9,GenBank,CAL35585,,,NCTC 11168,cadF,,,,,,,197,Campylobacter jejuni,354242,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,intestine-407 cell,outer membrane fibronectin-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32168837,PubMed,10.3390/microorganisms8030389,Microorganisms. 2020 Mar 11;8(3):389. doi: 10.3390/microorganisms8030389,kyrah.turner@wsu.edu,"Both CadF and FlpA were required for the delivery of the C. jejuni Cia effector proteins into the cytosol of host target cells, which was required for the C. jejuni invasion of host cells.",P K Talukdar 2020,2020,2 genes,Talukdar-2020-Molecular Dissection of the Camp,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16685,PHI:10563,UniProt,no data found,GenBank,,,,,flpA,,,,,,,197,Campylobacter jejuni,354242,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,intestine-407 cell,adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32168837,PubMed,10.3390/microorganisms8030389,Microorganisms. 2020 Mar 11;8(3):389. doi: 10.3390/microorganisms8030389,kyrah.turner@wsu.edu,"Both CadF and FlpA were required for the delivery of the C. jejuni Cia effector proteins into the cytosol of host target cells, which was required for the C. jejuni invasion of host cells.",P K Talukdar 2020,2020,2 genes,Talukdar-2020-Molecular Dissection of the Camp,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16686,PHI:10562,UniProt,Q0P8D9,GenBank,CAL35585,,,NCTC 11168,cadF,,,,,,PHI:10563,197,Campylobacter jejuni,354242,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,intestine-407 cell,outer membrane fibronectin-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32168837,PubMed,10.3390/microorganisms8030389,Microorganisms. 2020 Mar 11;8(3):389. doi: 10.3390/microorganisms8030389,kyrah.turner@wsu.edu,"Both CadF and FlpA were required for the delivery of the C. jejuni Cia effector proteins into the cytosol of host target cells, which was required for the C. jejuni invasion of host cells.",P K Talukdar 2020,2020,2 genes,Talukdar-2020-Molecular Dissection of the Camp,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16687,PHI:10563,UniProt,no data found,GenBank,,,,,flpA,,,,,,PHI:10562,197,Campylobacter jejuni,354242,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,intestine-407 cell,adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32168837,PubMed,10.3390/microorganisms8030389,Microorganisms. 2020 Mar 11;8(3):389. doi: 10.3390/microorganisms8030389,kyrah.turner@wsu.edu,"Both CadF and FlpA were required for the delivery of the C. jejuni Cia effector proteins into the cytosol of host target cells, which was required for the C. jejuni invasion of host cells.",P K Talukdar 2020,2020,2 genes,Talukdar-2020-Molecular Dissection of the Camp,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16688,PHI:10564,UniProt,D5AK26,GenBank,ADE32191,,,GZ1,endoSS (gh85),,,,,,,1307,Streptococcus suis,,ZY05719,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; blood; spleen; kidney,mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32443590,PubMed,10.3390/pathogens9050387,Pathogens. 2020 May 18;9(5):387. doi: 10.3390/pathogens9050387,yaohch@njau.edu.cn,"Both GH92 and EndoSS contributed to bacterial virulence, but that only EndoSS was required for optimal growth of SS2 in host serum.",J Ma 2020,2020,2 genes,Ma-2020-Streptococcus suis Uptakes Carbohydrat,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16689,PHI:10565,UniProt,D5AK25,GenBank,ADE32190,,,GZ1,gh92,,,,,,,1307,Streptococcus suis,,ZY05719,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; blood; spleen; kidney,"alpha-1,2-mannosidase, putative",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32443590,PubMed,10.3390/pathogens9050387,Pathogens. 2020 May 18;9(5):387. doi: 10.3390/pathogens9050387,yaohch@njau.edu.cn,"Both GH92 and EndoSS contributed to bacterial virulence, but that only EndoSS was required for optimal growth of SS2 in host serum.",J Ma 2020,2020,2 genes,Ma-2020-Streptococcus suis Uptakes Carbohydrat,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16690,PHI:10564,UniProt,D5AK26,GenBank,ADE32191,,,GZ1,endoSS (gh85),,,,,,,1307,Streptococcus suis,,ZY05719,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,serum,mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32443590,PubMed,10.3390/pathogens9050387,Pathogens. 2020 May 18;9(5):387. doi: 10.3390/pathogens9050387,yaohch@njau.edu.cn,"Both GH92 and EndoSS contributed to bacterial virulence, but that only EndoSS was required for optimal growth of SS2 in host serum.",J Ma 2020,2020,2 genes,Ma-2020-Streptococcus suis Uptakes Carbohydrat,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16691,PHI:10564,UniProt,D5AK26,GenBank,ADE32191,,,GZ1,endoSS (gh85),,,,,,,1307,Streptococcus suis,,ZY05719,infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32443590,PubMed,10.3390/pathogens9050387,Pathogens. 2020 May 18;9(5):387. doi: 10.3390/pathogens9050387,yaohch@njau.edu.cn,"Both GH92 and EndoSS contributed to bacterial virulence, but that only EndoSS was required for optimal growth of SS2 in host serum.",J Ma 2020,2020,2 genes,Ma-2020-Streptococcus suis Uptakes Carbohydrat,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16692,PHI:10565,UniProt,D5AK25,GenBank,ADE32190,,,GZ1,gh92,,,,,,,1307,Streptococcus suis,,ZY05719,infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,"alpha-1,2-mannosidase, putative",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32443590,PubMed,10.3390/pathogens9050387,Pathogens. 2020 May 18;9(5):387. doi: 10.3390/pathogens9050387,yaohch@njau.edu.cn,"Both GH92 and EndoSS contributed to bacterial virulence, but that only EndoSS was required for optimal growth of SS2 in host serum.",J Ma 2020,2020,2 genes,Ma-2020-Streptococcus suis Uptakes Carbohydrat,BATCH_101C,2020-08-01,MC,,,,,,,,,,,,,
,,Record 16693,PHI:10566,UniProt,Q7Z7W3,GenBank,CAC85614,,,DH14,beta2-tubulin,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei isolate K1,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,Beta2-tubulin housekeeping gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,32211008,PubMed,10.3389/fpls.2020.00253,Front Plant Sci. 2020 Mar 10;11:253. doi: 10.3389/fpls.2020.00253. eCollection 2020,salim.bourras@slu.se,"Transient HIGS of an essential housekeeping gene in B.g. tritici and B.g. hordei led to very similar, quantitative loss of virulence.",L K Schaefer 2020,2020,5 genes,Schaefer-2020-Cross-Kingdom RNAi of Pathogen E,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16694,PHI:10567,UniProt,Q7LLP2,GenBank,CAC85615,,,JIW28,beta2-tubulin,,,,,,,34373,Blumeria graminis,62690,f. sp. tritici isolate Bgt_JIW2,powdery mildew (barley),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,Beta2-tubulin housekeeping gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,32211008,PubMed,10.3389/fpls.2020.00253,Front Plant Sci. 2020 Mar 10;11:253. doi: 10.3389/fpls.2020.00253. eCollection 2020,salim.bourras@slu.se,"Transient HIGS of an essential housekeeping gene in B.g. tritici and B.g. hordei led to very similar, quantitative loss of virulence.",L K Schaefer 2020,2020,5 genes,Schaefer-2020-Cross-Kingdom RNAi of Pathogen E,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16695,PHI:10566,UniProt,Q7Z7W3,GenBank,CAC85614,,,DH14,beta2-tubulin,,,,,,,34373,Blumeria graminis,62688,f. sp. hordei isolate K1,powdery mildew (barley),monocots,4565,Triticum aestivum (related: bread wheat),cv. Chancellor,,,leaf,Beta2-tubulin housekeeping gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,32211008,PubMed,10.3389/fpls.2020.00253,Front Plant Sci. 2020 Mar 10;11:253. doi: 10.3389/fpls.2020.00253. eCollection 2020,salim.bourras@slu.se,"Transient HIGS of an essential housekeeping gene in B.g. tritici and B.g. hordei led to very similar, quantitative loss of virulence.",L K Schaefer 2020,2020,5 genes,Schaefer-2020-Cross-Kingdom RNAi of Pathogen E,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16696,PHI:10567,UniProt,Q7LLP2,GenBank,CAC85615,,,JIW28,beta2-tubulin,,,,,,,34373,Blumeria graminis,62690,f. sp. tritici isolate Bgt_JIW2,powdery mildew (barley),monocots,4565,Triticum aestivum (related: bread wheat),cv. Chancellor,,,leaf,Beta2-tubulin housekeeping gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,32211008,PubMed,10.3389/fpls.2020.00253,Front Plant Sci. 2020 Mar 10;11:253. doi: 10.3389/fpls.2020.00253. eCollection 2020,salim.bourras@slu.se,"Transient HIGS of an essential housekeeping gene in B.g. tritici and B.g. hordei led to very similar, quantitative loss of virulence.",L K Schaefer 2020,2020,5 genes,Schaefer-2020-Cross-Kingdom RNAi of Pathogen E,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16697,PHI:10568,UniProt,A0A2P0ZEB6,GenBank,,,,,SvrPm3a1/f 1,,,,,,,34373,Blumeria graminis,62690,f. sp. tritici isolate Bgt_JIW2,powdery mildew (barley),monocots,4565,Triticum aestivum (related: bread wheat),cv. Chancellor,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,32211008,PubMed,10.3389/fpls.2020.00253,Front Plant Sci. 2020 Mar 10;11:253. doi: 10.3389/fpls.2020.00253. eCollection 2020,salim.bourras@slu.se,"Targeted effectors effectively downregulated by HIGS, resulted in reduced fungal virulence on adult wheat plants.",L K Schaefer 2020,2020,5 genes,Schaefer-2020-Cross-Kingdom RNAi of Pathogen E,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16698,PHI:10569,UniProt,A0A061HMY2,GenBank,EPQ67234,,,96224,Bgt_Bcg-6,,,,,,,34373,Blumeria graminis,62690,f. sp. tritici isolate Bgt_JIW2,powdery mildew (barley),monocots,4565,Triticum aestivum (related: bread wheat),cv. Chancellor,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,32211008,PubMed,10.3389/fpls.2020.00253,Front Plant Sci. 2020 Mar 10;11:253. doi: 10.3389/fpls.2020.00253. eCollection 2020,salim.bourras@slu.se,"Targeted effectors effectively downregulated by HIGS, resulted in reduced fungal virulence on adult wheat plants.",L K Schaefer 2020,2020,5 genes,Schaefer-2020-Cross-Kingdom RNAi of Pathogen E,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16699,PHI:10570,UniProt,A0A061HK55,GenBank,EPQ67136,,,96224,Bgt_Bcg-7,,,,,,,34373,Blumeria graminis,62690,f. sp. tritici isolate Bgt_JIW2,powdery mildew (barley),monocots,4565,Triticum aestivum (related: bread wheat),cv. Chancellor,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,32211008,PubMed,10.3389/fpls.2020.00253,Front Plant Sci. 2020 Mar 10;11:253. doi: 10.3389/fpls.2020.00253. eCollection 2020,salim.bourras@slu.se,"Targeted effectors effectively downregulated by HIGS, resulted in reduced fungal virulence on adult wheat plants.",L K Schaefer 2020,2020,5 genes,Schaefer-2020-Cross-Kingdom RNAi of Pathogen E,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16700,PHI:10571,UniProt,A0A139Y2L7,GenBank,KYF45120,,,ARI,Rab11A,,Rab11A-DN (strain that over-expresses in a rapidly inducible manner an inactive GDP locked version of Rab11A),,,,,5811,Toxoplasma gondii,383379,RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,small GTPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32463830,PubMed,10.1371/journal.ppat.1008106,PLoS Pathog. 2020 May; 16(5): e1008106,sabrina.marion@pasteur-lille.fr,Rab11A-DN tachyzoites were severely impaired in surface attachment to human fibroblast (HFF) monolayers compared to Rab11A-WT parasites.,K Venugopal 2020,2020,1 gene,Venugopal-2020-Rab11A regulates dense granule,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16701,PHI:10572,UniProt,C6DIX1,GenBank,ACT13241,,,PC1,PccS1_003557,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,"two component transcriptional regulator, LuxR family",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16702,PHI:10572,UniProt,C6DIX1,GenBank,ACT13241,,,PC1,PccS1_003557,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,"two component transcriptional regulator, LuxR family",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16703,PHI:10572,UniProt,C6DIX1,GenBank,ACT13241,,,PC1,PccS1_003557,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,"two component transcriptional regulator, LuxR family",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16704,PHI:10573,UniProt,C6DEY6,GenBank,ACT14650,,,PC1,rsmA,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,ribosomal RNA small subunit methyltransferase A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16705,PHI:10574,UniProt,C6DDF7,GenBank,ACT14364,,,PC1,rpoS,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16706,PHI:10575,UniProt,C6DDJ0,GenBank,ACT14397,,,PC1,PccS1_000262,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,"transcriptional regulator, LysR family",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16707,PHI:10576,UniProt,C6DI95,GenBank,ACT15089,,,PC1,PccS1_001441,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,"transcriptional regulator, LysR family, MetR",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16708,PHI:10577,UniProt,C6DIJ6,GenBank,ACT11296,,,PC1,PccS1_001523,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,"transcriptional regulator, Fis family, Fis",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16709,PHI:10578,UniProt,C6DD61,GenBank,ACT12440,,,PC1,PccS1_002702,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,"transcriptional regulator, LysR family",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16710,PHI:10579,UniProt,no data found,GenBank,AFR03241,,,PCC21,hexR,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,DNA-binding transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16711,PHI:10580,UniProt,C6DI28,GenBank,ACT13201,,,PC1,PccS1_003516,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,"transcriptional regulator, GntR family",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16712,PHI:10581,UniProt,no data found,GenBank,,,,,detD,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16713,PHI:10582,UniProt,C6DKR0,GenBank,ACT13511,,,PC1,PccS1_003836,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,"transcriptional regulator, AraC family",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16714,PHI:10583,UniProt,C6DKY6,GenBank,ACT13587,,,PC1,betL,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,HTH-type transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16715,PHI:10584,UniProt,C6D9H7,GenBank,ACT13704,,,PC1,PccS1_004012,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,"LysR family transcriptional regulator, partial",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16716,PHI:10585,UniProt,no data found,GenBank,,,,,alsD,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16717,PHI:10586,UniProt,no data found,GenBank,,,,,dudB,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16718,PHI:10587,UniProt,A0A518VKX7,GenBank,QHP58461,,,JR1.1,kduD,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16719,PHI:10588,UniProt,no data found,GenBank,,,,,hmuU,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16720,PHI:10589,UniProt,no data found,GenBank,,,,,nasD,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16721,PHI:10590,UniProt,no data found,GenBank,,,,,nrtB,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16722,PHI:10591,UniProt,no data found,GenBank,KML70453,,,ICMP 5702,nrtA,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,monocots,69721,Zantedeschia aethiopica (related: arum-lily),,,,petiole,"ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16723,PHI:10592,UniProt,no data found,GenBank,PLY35781,,,F164,vgrG,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,type VI secretion system tip protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16724,PHI:10593,UniProt,C6DF39,GenBank,ACT12748,,,PC1,hcp,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,hydroxylamine reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16725,PHI:10594,UniProt,A0A1M5U341,GenBank,SHH57083,,,DSM 30168,impL,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16726,PHI:10595,UniProt,C6DC70,GenBank,ACT14164,,,PC1,clpB,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,chaperone protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16727,PHI:10596,UniProt,A0A1M5U2L7,GenBank,SHH56903,,,DSM 30168,impJ,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16728,PHI:10597,UniProt,C6DCT4,GenBank,ACT14259,,,PC1,hcp1,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,"type VI secretion system effector, Hcp1 family",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16729,PHI:10598,UniProt,no data found,GenBank,,,,,vgrG3,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16730,PHI:10599,UniProt,A0A518VKC1,GenBank,QDX97452,,,67,hrpN,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,type III secretion protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16731,PHI:10600,UniProt,B1A4F4,GenBank,ABZ05770,,,35,hrpA,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,Hrp pili protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16732,PHI:10601,UniProt,Q6WEG0,GenBank,AAQ73897,,,SCC1,hrpL,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,type III secretion sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16733,PHI:10602,UniProt,C6DIX6,GenBank,ACT13246,,,PC1,hrpQ,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,type III secretion apparatus protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16734,PHI:10603,UniProt,Q6WEF6,GenBank,AAQ73901,,,SCC1,hrcN,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,H(+)-transporting two-sector ATPase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16735,PHI:10592,UniProt,no data found,GenBank,PLY35781,,,F164,vgrG,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,type VI secretion system tip protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16736,PHI:10593,UniProt,C6DF39,GenBank,ACT12748,,,PC1,hcp,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,hydroxylamine reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16737,PHI:10594,UniProt,A0A1M5U341,GenBank,SHH57083,,,DSM 30168,impL,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16738,PHI:10595,UniProt,C6DC70,GenBank,ACT14164,,,PC1,clpB,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,chaperone protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16739,PHI:10596,UniProt,A0A1M5U2L7,GenBank,SHH56903,,,DSM 30168,impJ,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16740,PHI:10597,UniProt,C6DCT4,GenBank,ACT14259,,,PC1,hcp1,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,"type VI secretion system effector, Hcp1 family",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16741,PHI:10598,UniProt,no data found,GenBank,,,,,vgrG3,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16742,PHI:10599,UniProt,A0A518VKC1,GenBank,QDX97452,,,67,hrpN,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,type III secretion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16743,PHI:10600,UniProt,B1A4F4,GenBank,ABZ05770,,,35,hrpA,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,Hrp pili protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16744,PHI:10601,UniProt,Q6WEG0,GenBank,AAQ73897,,,SCC1,hrpL,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,type III secretion sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16745,PHI:10602,UniProt,C6DIX6,GenBank,ACT13246,,,PC1,hrpQ,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,type III secretion apparatus protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16746,PHI:10603,UniProt,Q6WEF6,GenBank,AAQ73901,,,SCC1,hrcN,,,,,,,554,Pectobacterium carotovorum,1150613,subsp. carotovorum strain PccS1,soft rot,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,H(+)-transporting two-sector ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32267092,PubMed,10.1111/mpp.12936,Mol Plant Pathol. 2020 Jun;21(6):871-891. doi: 10.1111/mpp.12936. Epub 2020 Apr 8,fanjq@njau.edu.cn,"The maceration caused by PccS1 was mainly due to the depression of plant callose deposition for resistance by the related bacterial genes and the superlytic ability of pectinolytic enzymes produced in PccS1, rather than the promotion of plant cell death elicited by the T3SS.",J Fan 2020,2020,32 genes,Fan-2020-Transcriptome of Pectobacterium carot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16747,PHI:10604,UniProt,Q9HZP1,GenBank,AE004722_1,,,PAO1,PvrA (PA2957),,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,TetR-family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16748,PHI:10605,UniProt,A0A0H2Z768,GenBank,ABJ10003,,,UCBPP-PA14,plcH (PA14 53360),,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,hemolyticphospholipaseC,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16749,PHI:10606,UniProt,A0A0H2ZCP3,GenBank,ABJ12550,,,UCBPP-PA14,fadD1 (PA14 21370),,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,long-chain-fatty-acid–CoAligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16750,PHI:10607,UniProt,A0A0H2ZFF9,GenBank,ABJ13110,,,UCBPP-PA14,fadD6 (PA14 13110),,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,probablemedium-chainacyl-CoAligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16751,PHI:10608,UniProt,Q9I610,GenBank,AE004488_1,,,PAO1,PA0508,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,probableacyl-CoAdehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16752,PHI:10606,UniProt,A0A0H2ZCP3,GenBank,ABJ12550,,,UCBPP-PA14,fadD1 (PA14 21370),,,,,,PHI:10607,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,long-chain-fatty-acid–CoAligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16753,PHI:10607,UniProt,A0A0H2ZFF9,GenBank,ABJ13110,,,UCBPP-PA14,fadD6 (PA14 13110),,,,,,PHI:10606,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,probablemedium-chainacyl-CoAligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16754,PHI:10606,UniProt,Q9HYU4,GenBank,AE004752_3,,,PAO1,fadD1,,,,,,PHI:10608,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,long-chain-fatty-acid–CoAligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16755,PHI:10608,UniProt,Q9I610,GenBank,AE004488_1,,,PAO1,PA0508,,,,,,PHI:10606,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,probableacyl-CoAdehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16756,PHI:10606,UniProt,A0A0H2ZCP3,GenBank,ABJ12550,,,UCBPP-PA14,fadD1 (PA14 21370),,,,,,PHI:10607; PHI:10608,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,long-chain-fatty-acid–CoAligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16757,PHI:10607,UniProt,A0A0H2ZFF9,GenBank,ABJ13110,,,UCBPP-PA14,fadD6 (PA14 13110),,,,,,PHI:10606; PHI:10608,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,probablemedium-chainacyl-CoAligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16758,PHI:10608,UniProt,Q9HYU4,GenBank,AE004752_3,,,PAO1,PA0508,,,,,,PHI:10606; PHI:10607,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,probableacyl-CoAdehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16759,PHI:10606,UniProt,A0A0H2ZCP3,GenBank,ABJ12550,,,UCBPP-PA14,fadD1 (PA14 21370),,,,,,PHI:10607; PHI:10608; PHI:10605,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,long-chain-fatty-acid–CoAligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16760,PHI:10607,UniProt,A0A0H2ZFF9,GenBank,ABJ13110,,,UCBPP-PA14,fadD6 (PA14 13110),,,,,,PHI:10606; PHI:10608; PHI:10605,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,probablemedium-chainacyl-CoAligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16761,PHI:10608,UniProt,Q9HYU4,GenBank,AE004752_3,,,PAO1,PA0508,,,,,,PHI:10606; PHI:10607; PHI:10605,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,probableacyl-CoAdehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16762,PHI:10605,UniProt,A0A0H2Z768,GenBank,ABJ10003,,,UCBPP-PA14,plcH (PA14 53360),,,,,,PHI:10606; PHI:10607; PHI:10608,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,hemolyticphospholipaseC,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32406921,PubMed,10.1093/nar/gkaa377,Nucleic Acids Res. 2020 Jun 19;48(11):5967-5985. doi: 10.1093/nar/gkaa377,wuweihui@nankai.edu.cn,PvrA directly regulated genes involved in phosphatidylcholine utilization and fatty acid catabolism.,X Pan 2020,2020,5 genes,Pan-2020-PvrA is a novel regulator that contri,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16763,PHI:10609,UniProt,Q8I2D9,GenBank,CAD48950,,,3D7,GEXP07 (PF3D7_0113900),chromosome 1,,,,,,5833,Plasmodium falciparum,,CS2,malaria,primates,9606,Homo sapiens (related: human),,,,erythrocyte,CX3CL1-binding protein 1,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene deletion: full,,,YVS,32184257,PubMed,10.1128/mBio.03320-19,mBio. 2020 Mar 17;11(2):e03320-19. doi: 10.1128/mBio.03320-19,matthew.dixon@unimelb.edu.au,"Gene knockout of GEXP07 led to a PfEMP1 trafficking defect, increased deformability, and increased cellular fragility.",E McHugh 2020,2020,1 gene,McHugh-2020-Role of Plasmodium falciparum Prot,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16764,PHI:10610,UniProt,A0A380UNQ5,GenBank,SUU19893,,,NCTC13305,lpxA,,LpxA V128- (deletion of 128 valine),,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,multifunctional fusion protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32373082,PubMed,10.3389/fmicb.2020.00573,Front Microbiol. 2020 Apr 17;11:573,kamoshida@mb.kyoto-phu.ac.jp,LPS-defective A. baumannii stimulated lower levels of ROS and inflammatory cytokines in neutrophils.,G Kamoshida 2020,2020,3 genes,Kamoshida-2020-Lipopolysaccharide-Deficient Ac,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16765,PHI:10611,UniProt,V5VDY4,GenBank,AKA31479,,,AB5075-UW,lpxD,,LpxD E312* (truncation of C-terminal 45 aa)T LpxC D104E,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,UDP-3-O-acylglucosamine N-acyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32373082,PubMed,10.3389/fmicb.2020.00573,Front Microbiol. 2020 Apr 17;11:573,kamoshida@mb.kyoto-phu.ac.jp,LPS-defective A. baumannii stimulated lower levels of ROS and inflammatory cytokines in neutrophils.,G Kamoshida 2020,2020,3 genes,Kamoshida-2020-Lipopolysaccharide-Deficient Ac,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16766,PHI:10612,UniProt,B2I1I9,GenBank,ACC58837,,,ACICU,lpxC,,LpxC F191L,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,UDP-3-O-acyl-N-acetylglucosamine deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32373082,PubMed,10.3389/fmicb.2020.00573,Front Microbiol. 2020 Apr 17;11:573,kamoshida@mb.kyoto-phu.ac.jp,LPS-defective A. baumannii stimulated lower levels of ROS and inflammatory cytokines in neutrophils.,G Kamoshida 2020,2020,3 genes,Kamoshida-2020-Lipopolysaccharide-Deficient Ac,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16767,PHI:10612,UniProt,B2I1I9,GenBank,ACC58837,,,ACICU,lpxC,,LpxC D141* (truncation of C-terminal 160 aa),,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,neutrophil,UDP-3-O-acyl-N-acetylglucosamine deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32373082,PubMed,10.3389/fmicb.2020.00573,Front Microbiol. 2020 Apr 17;11:573,kamoshida@mb.kyoto-phu.ac.jp,LPS-defective A. baumannii stimulated lower levels of ROS and inflammatory cytokines in neutrophils.,G Kamoshida 2020,2020,3 genes,Kamoshida-2020-Lipopolysaccharide-Deficient Ac,BATCH_101D,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16768,PHI:10613,UniProt,P71622,GenBank,CCP45631,,,H37Rv,VapB22,,,,VapC22,UniProt: P71623; GenBank: CCP45630,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,antitoxin,,,,reduced virulence,,,,,,,,,,no,H2O2; NaNO2; SDS; isoniazid; rifampicin; ethambutol; levofloxacin,H2O2: CHEBI:16240; NaNO2: CHEBI:78870; SDS: CHEBI:8984; isoniazid: CHEBI:6030; rifampicin: CHEBI:28077; ethambutol: CHEBI:4877; levofloxacin: CHEBI:63598,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32537511,PubMed,10.1126/sciadv.aba6944,Sci Adv. 2020 Jun 3;6(23):eaba6944,ramandeep@thsti.res.in,Both the ΔvapC22 mutant and VapB22 overexpression strains of M. tuberculosis were susceptible to killing upon exposure to oxidative stress and showed attenuated growth in guinea pigs and mice.,S Agarwal 2020,2020,2 genes,Agarwal-2020-VapBC22 toxin-antitoxin system fr,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16769,PHI:10614,UniProt,P71623,GenBank,CCP45630,,,H37Rv,VapC22,,,,VapB22,UniProt: P71622; GenBank: CCP45631,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,ribonuclease,,,,reduced virulence,,,,,,,,increased,,no,H2O2; NaNO2; SDS; isoniazid; rifampicin; ethambutol; levofloxacin,H2O2: CHEBI:16240; NaNO2: CHEBI:78870; SDS: CHEBI:8984; isoniazid: CHEBI:6030; rifampicin: CHEBI:28077; ethambutol: CHEBI:4877; levofloxacin: CHEBI:63598,,,,,gene deletion: full; gene complementation,,,YVS,32537511,PubMed,10.1126/sciadv.aba6944,Sci Adv. 2020 Jun 3;6(23):eaba6944,ramandeep@thsti.res.in,Both the ΔvapC22 mutant and VapB22 overexpression strains of M. tuberculosis were susceptible to killing upon exposure to oxidative stress and showed attenuated growth in guinea pigs and mice.,S Agarwal 2020,2020,2 genes,Agarwal-2020-VapBC22 toxin-antitoxin system fr,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16770,PHI:10613,UniProt,P71622,GenBank,CCP45631,,,H37Rv,VapB22,,,,VapC22,UniProt: P71623; GenBank: CCP45630,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10141,Cavia porcellus (related: Domestic Guinea pig),,,,lung; spleen,antitoxin,,,,reduced virulence,,,,,,,,,,no,H2O2; NaNO2; SDS; isoniazid; rifampicin; ethambutol; levofloxacin,H2O2: CHEBI:16240; NaNO2: CHEBI:78870; SDS: CHEBI:8984; isoniazid: CHEBI:6030; rifampicin: CHEBI:28077; ethambutol: CHEBI:4877; levofloxacin: CHEBI:63598,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32537511,PubMed,10.1126/sciadv.aba6944,Sci Adv. 2020 Jun 3;6(23):eaba6944,ramandeep@thsti.res.in,Both the ΔvapC22 mutant and VapB22 overexpression strains of M. tuberculosis were susceptible to killing upon exposure to oxidative stress and showed attenuated growth in guinea pigs and mice.,S Agarwal 2020,2020,2 genes,Agarwal-2020-VapBC22 toxin-antitoxin system fr,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16771,PHI:10614,UniProt,P71623,GenBank,CCP45630,,,H37Rv,VapC22,,,,VapB22,UniProt: P71622; GenBank: CCP45631,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10141,Cavia porcellus (related: Domestic Guinea pig),,,,lung; spleen,ribonuclease,,,,reduced virulence,,,,,,,,increased,,no,H2O2; NaNO2; SDS; isoniazid; rifampicin; ethambutol; levofloxacin,H2O2: CHEBI:16240; NaNO2: CHEBI:78870; SDS: CHEBI:8984; isoniazid: CHEBI:6030; rifampicin: CHEBI:28077; ethambutol: CHEBI:4877; levofloxacin: CHEBI:63598,,,,,gene deletion: full; gene complementation,,,YVS,32537511,PubMed,10.1126/sciadv.aba6944,Sci Adv. 2020 Jun 3;6(23):eaba6944,ramandeep@thsti.res.in,Both the ΔvapC22 mutant and VapB22 overexpression strains of M. tuberculosis were susceptible to killing upon exposure to oxidative stress and showed attenuated growth in guinea pigs and mice.,S Agarwal 2020,2020,2 genes,Agarwal-2020-VapBC22 toxin-antitoxin system fr,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16772,PHI:10615,UniProt,I1RW14,GenBank,CEF76821,,,PH-1,FgCrpA (FGRAMPH1_01G10037),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 10,,,spike,P-type ATPase transporter,,,,reduced virulence,,,,,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32676062,PubMed,10.3389/fmicb.2020.01392,Front Microbiol. 2020 Jun 26;11:1392,npkeller@wisc.edu,ΔFgCrpA and ΔFgAceA were reduced in virulence in flowering wheat heads and synthesized decreased amounts of the mycotoxin deoxynivalenol when challenged with excess Cu.,X Liu 2020,2020,3 genes,Liu-2020-Copper Tolerance Mediated by FgAceA a,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16773,PHI:10616,UniProt,I1RVU8,GenBank,CEF76724,,,PH-1,FgAceA (FGRAMPH1_01G09843),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 10,,,spike,Cu fist transcription factor,,,,reduced virulence,,,,,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32676062,PubMed,10.3389/fmicb.2020.01392,Front Microbiol. 2020 Jun 26;11:1392,npkeller@wisc.edu,ΔFgCrpA and ΔFgAceA were reduced in virulence in flowering wheat heads and synthesized decreased amounts of the mycotoxin deoxynivalenol when challenged with excess Cu.,X Liu 2020,2020,3 genes,Liu-2020-Copper Tolerance Mediated by FgAceA a,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16774,PHI:10615,UniProt,I1RW14,GenBank,CEF76821,,,PH-1,FgCrpA (FGRAMPH1_01G10037),chromosome 2,,,,,PHI:10616,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 10,,,spike,P-type ATPase transporter,,,,reduced virulence,,,,,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32676062,PubMed,10.3389/fmicb.2020.01392,Front Microbiol. 2020 Jun 26;11:1392,npkeller@wisc.edu,ΔFgCrpA and ΔFgAceA were reduced in virulence in flowering wheat heads and synthesized decreased amounts of the mycotoxin deoxynivalenol when challenged with excess Cu.,X Liu 2020,2020,3 genes,Liu-2020-Copper Tolerance Mediated by FgAceA a,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16775,PHI:10616,UniProt,I1RVU8,GenBank,CEF76724,,,PH-1,FgAceA (FGRAMPH1_01G09843),chromosome 2,,,,,PHI:10615,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 10,,,spike,Cu fist transcription factor,,,,reduced virulence,,,,,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32676062,PubMed,10.3389/fmicb.2020.01392,Front Microbiol. 2020 Jun 26;11:1392,npkeller@wisc.edu,ΔFgCrpA and ΔFgAceA were reduced in virulence in flowering wheat heads and synthesized decreased amounts of the mycotoxin deoxynivalenol when challenged with excess Cu.,X Liu 2020,2020,3 genes,Liu-2020-Copper Tolerance Mediated by FgAceA a,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16776,PHI:10617,UniProt,I1RVA6,GenBank,CEF76443,,,PH-1,FgCrdA (FGRAMPH1_01G09281),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 10,,,spike,metallothionein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32676062,PubMed,10.3389/fmicb.2020.01392,Front Microbiol. 2020 Jun 26;11:1392,npkeller@wisc.edu,Deletion of FgCrpA but not FgCrdA resulted in reduced tolerance to Cu toxicity.,X Liu 2020,2020,3 genes,Liu-2020-Copper Tolerance Mediated by FgAceA a,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16777,PHI:10618,UniProt,A0A384JMC1,GenBank,ATZ51739,,,B05.10,Bcin07g03260,BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,non-GPCR membrane-bound CFEM-containing protein,,,,reduced virulence,,,,,,wild type,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32674341,PubMed,10.3390/microorganisms8071043,Microorganisms. 2020 Jul 14;8(7):1043,aryeharel@volcani.agri.gov.il,ΔCFEM-Bcin07g03260 mutants showed significantly reduced progression of a necrotic lesion on tomato.,G C Arya 2020,2020,1 gene,Arya-2020-Characterization of the Role of a No,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16778,PHI:10619,UniProt,Q87XK3,GenBank,AAO57631,,,DC3000,aauS (PSPTO_4175),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,"two-component system, sensor histidine kinase",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32673374,PubMed,10.1371/journal.ppat.1008680,PLoS Pathog. 2020 Jul 16;16(7):e1008680,anderje2@oregonstate.edu,"Mutants of P. syringae strain DC3000 lacking aauS, aauR or aatJ had decreased T3SS deployment and virulence during infection of Arabidopsis.",Q Yan 2020,2020,5 genes,Yan-2020-Ancient co-option of an amino acid AB,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16779,PHI:10620,UniProt,A0A1I5AAS6,GenBank,NAO52100,,,P108,aauR,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,"two-component system, response regulator",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32673374,PubMed,10.1371/journal.ppat.1008680,PLoS Pathog. 2020 Jul 16;16(7):e1008680,anderje2@oregonstate.edu,"Mutants of P. syringae strain DC3000 lacking aauS, aauR or aatJ had decreased T3SS deployment and virulence during infection of Arabidopsis.",Q Yan 2020,2020,5 genes,Yan-2020-Ancient co-option of an amino acid AB,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16780,PHI:10621,UniProt,Q87XK7,GenBank,AAO57627,,,DC3000,aatJ (PSPTO_4171),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,substrate-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32673374,PubMed,10.1371/journal.ppat.1008680,PLoS Pathog. 2020 Jul 16;16(7):e1008680,anderje2@oregonstate.edu,"Mutants of P. syringae strain DC3000 lacking aauS, aauR or aatJ had decreased T3SS deployment and virulence during infection of Arabidopsis.",Q Yan 2020,2020,5 genes,Yan-2020-Ancient co-option of an amino acid AB,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16781,PHI:10622,UniProt,Q887C8,GenBank,AAO54901,,,DC3000,hrpR (PSPTO_1379),,deletion of 20-bp region of hrpRS promoter containing AauR-binding motif,,,,PHI:10623,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,type III transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,promoter mutation,,,YVS,32673374,PubMed,10.1371/journal.ppat.1008680,PLoS Pathog. 2020 Jul 16;16(7):e1008680,anderje2@oregonstate.edu,"Mutants of P. syringae strain DC3000 lacking aauS, aauR or aatJ had decreased T3SS deployment and virulence during infection of Arabidopsis.",Q Yan 2020,2020,5 genes,Yan-2020-Ancient co-option of an amino acid AB,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16782,PHI:10623,UniProt,Q887C7,GenBank,AAO54902,,,DC3000,hrpS,,AauR-binding motif,,,,PHI:10622,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,type III transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,promoter mutation,,,YVS,32673374,PubMed,10.1371/journal.ppat.1008680,PLoS Pathog. 2020 Jul 16;16(7):e1008680,anderje2@oregonstate.edu,"Mutants of P. syringae strain DC3000 lacking aauS, aauR or aatJ had decreased T3SS deployment and virulence during infection of Arabidopsis.",Q Yan 2020,2020,5 genes,Yan-2020-Ancient co-option of an amino acid AB,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16783,PHI:10620,UniProt,A0A1I5AAS6,GenBank,NAO52100,,,P108,aauR,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,"two-component system, response regulator",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32673374,PubMed,10.1371/journal.ppat.1008680,PLoS Pathog. 2020 Jul 16;16(7):e1008680,anderje2@oregonstate.edu,"An aauR deletion mutant of P. syringae strain B728a, a bean pathogen, had decreased T3SS expression and growth in host plants.",Q Yan 2020,2020,5 genes,Yan-2020-Ancient co-option of an amino acid AB,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16784,PHI:10624,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,CaArv1,chromosome 3,,,CaErg11,UniProt: P10613; GenBank: CAA31658,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,reduced virulence,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence using a disseminated candidiasis mouse model.,M L Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16785,PHI:10624,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,CaArv1,chromosome 3,C3A,,CaErg11,UniProt: P10613; GenBank: CAA31658,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,unaffected pathogenicity,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence using a disseminated candidiasis mouse model.,M L Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16786,PHI:10624,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,CaArv1,chromosome 3,C28A,,CaErg11,UniProt: P10613; GenBank: CAA31658,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,reduced virulence,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence using a disseminated candidiasis mouse model.,M L Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16787,PHI:10624,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,CaArv1,chromosome 3,Y38A,,CaErg11,UniProt: P10613; GenBank: CAA31658,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,unaffected pathogenicity,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence using a disseminated candidiasis mouse model.,M L Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16788,PHI:10624,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,CaArv1,chromosome 3,C3A,,CaErg11,UniProt: P10613; GenBank: CAA31658,PHI:10625,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,unaffected pathogenicity,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence using a disseminated candidiasis mouse model.,M L Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16789,PHI:10625,UniProt,P10613,GenBank,CAA31658,,,SC5314,CaErg11,,Y132L F145L,,CaArv1,UniProt: Q5ANH2; GenBank: AOW28488,PHI:10624,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,lanosterol 14-alpha demethylase,,,,unaffected pathogenicity,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence using a disseminated candidiasis mouse model.,M L Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16790,PHI:10624,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,CaArv1,chromosome 3,C28A,,CaErg11,UniProt: P10613; GenBank: CAA31658,PHI:10625,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,reduced virulence,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence using a disseminated candidiasis mouse model.,M L Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16791,PHI:10625,UniProt,P10613,GenBank,CAA31658,,,SC5314,CaErg11,,Y132L F145L,,CaArv1,UniProt: Q5ANH2; GenBank: AOW28488,PHI:10624,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,lanosterol 14-alpha demethylase,,,,reduced virulence,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence using a disseminated candidiasis mouse model.,M L Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16792,PHI:10624,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,CaArv1,chromosome 3,C38A,,CaErg11,UniProt: P10613; GenBank: CAA31658,PHI:10625,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,unaffected pathogenicity,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence using a disseminated candidiasis mouse model.,M L Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16793,PHI:10625,UniProt,P10613,GenBank,CAA31658,,,SC5314,CaErg11,,Y132L F145L,,CaArv1,UniProt: Q5ANH2; GenBank: AOW28488,PHI:10624,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,lanosterol 14-alpha demethylase,,,,unaffected pathogenicity,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence using a disseminated candidiasis mouse model.,M L Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16794,PHI:10626,UniProt,Q4WQJ0,GenBank,EAL89494,,,Af293,TrxR (Afu4g12990),chromosome 4,tetOFF:trxR promoter replacement,,,,,746128,Aspergillus fumigatus,,AfS35,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,thioredoxin reductase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; voriconazole; doxycycline,H2O2: CHEBI:16240; voriconazole: CHEBI:10023; doxycycline: CHEBI:50845,,,,,promoter mutation,,,YVS,32670238,PubMed,10.3389/fmicb.2020.01383,Front Microbiol. 2020 Jun 25;11:1383,sven.krappmann@uk-erlangen.de,"The tetOFF:trxR strain mirrored virulence capacities of the wild-type progenitor in the absence of doxycycline, while doxycycline treatment resulted in a signi?cantly elevated survival rate of 40% for the infected cohort.",J Binder 2020,2020,1 gene,Binder-2020-The Essential Thioredoxin Reductas,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16795,PHI:10627,UniProt,Q4WTI4,GenBank,EAL90248,,,Af293,RglT (Afu1g09190),chromosome 1,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,C6 Zn cluster-type transcription factor,,,gliotoxin biosynthesis,reduced virulence,,,,,,,,,,no,acrolein; menadione; t-butyl hydroperoxide,acrolein: CHEBI:15368; menadione: CHEBI:28869; t-butyl hydroperoxide: CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,32667960,PubMed,10.1371/journal.ppat.1008645,PLoS Pathog. 2020 Jul 15;16(7):e1008645,koonhowong3@gmail.com,The ΔrglT strain was hypovirulent in a chemotherapeutic murine model of IPA.,L N A Ries 2020,2020,1 gene,Ries-2020-The Aspergillus fumigatus transcript,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16796,PHI:10627,UniProt,Q4WTI4,GenBank,EAL90248,,,Af293,RglT (Afu1g09190),chromosome 1,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,C6 Zn cluster-type transcription factor,,,gliotoxin biosynthesis,reduced virulence,,,,,,,,,,no,acrolein; menadione; t-butyl hydroperoxide,acrolein: CHEBI:15368; menadione: CHEBI:28869; t-butyl hydroperoxide: CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,32667960,PubMed,10.1371/journal.ppat.1008645,PLoS Pathog. 2020 Jul 15;16(7):e1008645,koonhowong3@gmail.com,The ΔrglT strain was found to be significantly more susceptible to macrophage-mediated phagocytosis and killing.,L N A Ries 2020,2020,1 gene,Ries-2020-The Aspergillus fumigatus transcript,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16797,PHI:10628,UniProt,C5AA67,GenBank,ACR27590,,,BGR1,tssD1 (bglu_1g03910),chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16798,PHI:10629,UniProt,C5ALD1,GenBank,ACR30632,,,BGR1,tssD2 (bglu_2g01440),chromosome 2,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16799,PHI:10630,UniProt,C5AHX3,GenBank,ACR31503,,,BGR1,tssD4 (bglu_2g11090),chromosome 2,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16800,PHI:10631,UniProt,C5AMW5,GenBank,ACR31166,,,BGR1,tssD5 (bglu_2g07470),chromosome 2,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16801,PHI:10628,UniProt,C5AA67,GenBank,ACR27590,,,BGR1,tssD1 (bglu_1g03910),chromosome 1,,,,,PHI:10629,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16802,PHI:10629,UniProt,C5ALD1,GenBank,ACR30632,,,BGR1,tssD2 (bglu_2g01440),chromosome 2,,,,,PHI:10628,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16803,PHI:10630,UniProt,C5AHX3,GenBank,ACR31503,,,BGR1,tssD4 (bglu_2g11090),chromosome 2,,,,,PHI:10631,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16804,PHI:10631,UniProt,C5AMW5,GenBank,ACR31166,,,BGR1,tssD5 (bglu_2g07470),chromosome 2,,,,,PHI:10630,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16805,PHI:10628,UniProt,C5AA67,GenBank,ACR27590,,,BGR1,tssD1 (bglu_1g03910),chromosome 1,,,,,PHI:10629; PHI:10630; PHI:10631,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16806,PHI:10629,UniProt,C5ALD1,GenBank,ACR30632,,,BGR1,tssD2 (bglu_2g01440),chromosome 2,,,,,PHI:10628; PHI:10630; PHI:10631,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16807,PHI:10630,UniProt,C5AHX3,GenBank,ACR31503,,,BGR1,tssD4 (bglu_2g11090),chromosome 2,,,,,PHI:10628; PHI:10629; PHI:10631,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16808,PHI:10631,UniProt,C5AMW5,GenBank,ACR31166,,,BGR1,tssD5 (bglu_2g07470),chromosome 2,,,,,PHI:10628; PHI:10629; PHI:10630,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32643866,PubMed,10.1111/mpp.12966. Epub 2020 Jul 9,Mol Plant Pathol. 2020 Aug;21(8):1055-1069,yseo2011@pusan.ac.kr,"Of the tested tssD mutants (ΔtssD1, ΔtssD2, ΔtssD4, ΔtssD5, ΔtssD12, ΔtssD45, and ΔtssD1245), only ΔtssD4, ΔtssD5, ΔtssD45, and ΔtssD1245 showed reduced virulenc suggesting that the genes tssD4 and tssD5 contributed to virulence towards rice plants.",N Kim 2020,2020,4 genes,Kim-2020-Type VI secretion systems of plant-pa,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16809,PHI:10632,UniProt,D0NVB5,GenBank,EEY66592,,,T30-4,Avr1 (PITG_16663),,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32636869,PubMed,10.3389/fpls.2020.00919,Front Plant Sci. 2020 Jun 19;11:919,wxshan@nwafu.edu.cn,"Transient expression of 10 known avirulence genes showed that PiAvr4 and PiAvr8 (PiAvrsmira2) could induce HR in Qingshu9, and PiAvrvnt1.1 in Longshu7, respectively.",A S M Elnahal 2020,2020,10 genes,Elnahal-2020-Identification of Natural Resista,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16810,PHI:10633,UniProt,D0NDJ8,GenBank,EEY56155,,,T30-4,Avr2 (PITG_22870),,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32636869,PubMed,10.3389/fpls.2020.00919,Front Plant Sci. 2020 Jun 19;11:919,wxshan@nwafu.edu.cn,"Transient expression of 10 known avirulence genes showed that PiAvr4 and PiAvr8 (PiAvrsmira2) could induce HR in Qingshu9, and PiAvrvnt1.1 in Longshu7, respectively.",A S M Elnahal 2020,2020,10 genes,Elnahal-2020-Identification of Natural Resista,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16811,PHI:10634,UniProt,D0NPN8,GenBank,EEY62600,,,T30-4,Avr3a (PITG_14371),,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32636869,PubMed,10.3389/fpls.2020.00919,Front Plant Sci. 2020 Jun 19;11:919,wxshan@nwafu.edu.cn,"Transient expression of 10 known avirulence genes showed that PiAvr4 and PiAvr8 (PiAvrsmira2) could induce HR in Qingshu9, and PiAvrvnt1.1 in Longshu7, respectively.",A S M Elnahal 2020,2020,10 genes,Elnahal-2020-Identification of Natural Resista,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16812,PHI:10635,UniProt,D0NXM3,GenBank,EEY67823,,,T30-4,Avr3b (PITG_18215),,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32636869,PubMed,10.3389/fpls.2020.00919,Front Plant Sci. 2020 Jun 19;11:919,wxshan@nwafu.edu.cn,"Transient expression of 10 known avirulence genes showed that PiAvr4 and PiAvr8 (PiAvrsmira2) could induce HR in Qingshu9, and PiAvrvnt1.1 in Longshu7, respectively.",A S M Elnahal 2020,2020,10 genes,Elnahal-2020-Identification of Natural Resista,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16813,PHI:10636,UniProt,B1NNT7,GenBank,EEY53788,,,T30-4,Avr4 (PITG_07387),,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32636869,PubMed,10.3389/fpls.2020.00919,Front Plant Sci. 2020 Jun 19;11:919,wxshan@nwafu.edu.cn,"Transient expression of 10 known avirulence genes showed that PiAvr4 and PiAvr8 (PiAvrsmira2) could induce HR in Qingshu9, and PiAvrvnt1.1 in Longshu7, respectively.",A S M Elnahal 2020,2020,10 genes,Elnahal-2020-Identification of Natural Resista,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16814,PHI:10637,UniProt,D0P3S7,GenBank,EEY61733,,,T30-4,Avrblb1 (PITG_21388),,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32636869,PubMed,10.3389/fpls.2020.00919,Front Plant Sci. 2020 Jun 19;11:919,wxshan@nwafu.edu.cn,"Transient expression of 10 known avirulence genes showed that PiAvr4 and PiAvr8 (PiAvrsmira2) could induce HR in Qingshu9, and PiAvrvnt1.1 in Longshu7, respectively.",A S M Elnahal 2020,2020,10 genes,Elnahal-2020-Identification of Natural Resista,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16815,PHI:10638,UniProt,D0P1A8,GenBank,EEY54134,,,T30-4,Avrblb2 (PITG_20300),,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32636869,PubMed,10.3389/fpls.2020.00919,Front Plant Sci. 2020 Jun 19;11:919,wxshan@nwafu.edu.cn,"Transient expression of 10 known avirulence genes showed that PiAvr4 and PiAvr8 (PiAvrsmira2) could induce HR in Qingshu9, and PiAvrvnt1.1 in Longshu7, respectively.",A S M Elnahal 2020,2020,10 genes,Elnahal-2020-Identification of Natural Resista,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16816,PHI:10639,UniProt,D0N8M0,GenBank,EEY53905,,,T30-4,Avrsmira1 (PITG_07550),,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32636869,PubMed,10.3389/fpls.2020.00919,Front Plant Sci. 2020 Jun 19;11:919,wxshan@nwafu.edu.cn,"Transient expression of 10 known avirulence genes showed that PiAvr4 and PiAvr8 (PiAvrsmira2) could induce HR in Qingshu9, and PiAvrvnt1.1 in Longshu7, respectively.",A S M Elnahal 2020,2020,10 genes,Elnahal-2020-Identification of Natural Resista,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16817,PHI:10640,UniProt,D0N8M8,GenBank,EEY53913,,,T30-4,Avrsmira2/Avr8 (PITG_07558),,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32636869,PubMed,10.3389/fpls.2020.00919,Front Plant Sci. 2020 Jun 19;11:919,wxshan@nwafu.edu.cn,"Transient expression of 10 known avirulence genes showed that PiAvr4 and PiAvr8 (PiAvrsmira2) could induce HR in Qingshu9, and PiAvrvnt1.1 in Longshu7, respectively.",A S M Elnahal 2020,2020,10 genes,Elnahal-2020-Identification of Natural Resista,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16818,PHI:10641,UniProt,D0NTY1,GenBank,EEY65105,,,T30-4,Avrvnt1 (PITG_16294),,,,,,,4787,Phytophthora infestans,,,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32636869,PubMed,10.3389/fpls.2020.00919,Front Plant Sci. 2020 Jun 19;11:919,wxshan@nwafu.edu.cn,"Transient expression of 10 known avirulence genes showed that PiAvr4 and PiAvr8 (PiAvrsmira2) could induce HR in Qingshu9, and PiAvrvnt1.1 in Longshu7, respectively.",A S M Elnahal 2020,2020,10 genes,Elnahal-2020-Identification of Natural Resista,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16819,PHI:10642,UniProt,Q59RW5,GenBank,AOW30374,,,SC5314,hxk1,chromosome 6,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,N-acetylglucosamine kinase 1,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16820,PHI:10643,UniProt,P83776,GenBank,AOW31187,,,SC5314,hxk2,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,hexokinase 2,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16821,PHI:10642,UniProt,Q59RW5,GenBank,AOW30374,,,SC5314,hxk1,chromosome 6,,,,,PHI:10643,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,N-acetylglucosamine kinase 1,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16822,PHI:10643,UniProt,P83776,GenBank,AOW31187,,,SC5314,hxk2,chromosome R,,,,,PHI:10642,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,hexokinase 2,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16823,PHI:10644,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,glk1,chromosome R,,,,,PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphotransferase,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16824,PHI:10645,UniProt,Q59RR7,GenBank,AOW31442,,,SC5314,glk4,chromosome R,,,,,PHI:10644,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphotransferase,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16825,PHI:10642,UniProt,Q59RW5,GenBank,AOW30374,,,SC5314,hxk1,chromosome 6,,,,,PHI:10644; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,N-acetylglucosamine kinase 1,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16826,PHI:10644,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,glk1,chromosome R,,,,,PHI:10642; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphotransferase,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16827,PHI:10645,UniProt,Q59RR7,GenBank,AOW31442,,,SC5314,glk4,chromosome R,,,,,PHI:10642; PHI:10644,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphotransferase,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16828,PHI:10643,UniProt,P83776,GenBank,AOW31187,,,SC5314,hxk2,chromosome R,,,,,PHI:10644; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,hexokinase 2,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16829,PHI:10644,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,glk1,chromosome R,,,,,PHI:10643; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphotransferase,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16830,PHI:10645,UniProt,Q59RR7,GenBank,AOW31442,,,SC5314,glk4,chromosome R,,,,,PHI:10643; PHI:10644,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphotransferase,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16831,PHI:10642,UniProt,Q59RW5,GenBank,AOW30374,,,SC5314,hxk1,chromosome 6,,,,,PHI:10643; PHI:10644; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,N-acetylglucosamine kinase 1,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16832,PHI:10643,UniProt,P83776,GenBank,AOW31187,,,SC5314,hxk2,chromosome R,,,,,PHI:10642; PHI:10644; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,hexokinase 2,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16833,PHI:10644,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,glk1,chromosome R,,,,,PHI:10642; PHI:10643; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphotransferase,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16834,PHI:10645,UniProt,Q59RR7,GenBank,AOW31442,,,SC5314,glk4,chromosome R,,,,,PHI:10642; PHI:10643; PHI:10644,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,phosphotransferase,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16835,PHI:10642,UniProt,Q59RW5,GenBank,AOW30374,,,SC5314,hxk1,chromosome 6,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,N-acetylglucosamine kinase 1,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16836,PHI:10643,UniProt,P83776,GenBank,AOW31187,,,SC5314,hxk2,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,hexokinase 2,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16837,PHI:10642,UniProt,Q59RW5,GenBank,AOW30374,,,SC5314,hxk1,chromosome 6,,,,,PHI:10643,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,N-acetylglucosamine kinase 1,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16838,PHI:10643,UniProt,P83776,GenBank,AOW31187,,,SC5314,hxk2,chromosome R,,,,,PHI:10642,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,hexokinase 2,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16839,PHI:10644,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,glk1,chromosome R,,,,,PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,phosphotransferase,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16840,PHI:10645,UniProt,Q59RR7,GenBank,AOW31442,,,SC5314,glk4,chromosome R,,,,,PHI:10644,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,phosphotransferase,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16841,PHI:10642,UniProt,Q59RW5,GenBank,AOW30374,,,SC5314,hxk1,chromosome 6,,,,,PHI:10644; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,N-acetylglucosamine kinase 1,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16842,PHI:10644,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,glk1,chromosome R,,,,,PHI:10642; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,phosphotransferase,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16843,PHI:10645,UniProt,Q59RR7,GenBank,AOW31442,,,SC5314,glk4,chromosome R,,,,,PHI:10642; PHI:10644,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,phosphotransferase,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16844,PHI:10643,UniProt,P83776,GenBank,AOW31187,,,SC5314,hxk2,chromosome R,,,,,PHI:10644; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,hexokinase 2,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16845,PHI:10644,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,glk1,chromosome R,,,,,PHI:10643; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,phosphotransferase,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16846,PHI:10645,UniProt,Q59RR7,GenBank,AOW31442,,,SC5314,glk4,chromosome R,,,,,PHI:10643; PHI:10644,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,phosphotransferase,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16847,PHI:10642,UniProt,Q59RW5,GenBank,AOW30374,,,SC5314,hxk1,chromosome 6,,,,,PHI:10643; PHI:10644; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,N-acetylglucosamine kinase 1,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16848,PHI:10643,UniProt,P83776,GenBank,AOW31187,,,SC5314,hxk2,chromosome R,,,,,PHI:10642; PHI:10644; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,hexokinase 2,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16849,PHI:10644,UniProt,Q59TZ8,GenBank,AOW31410,,,SC5314,glk1,chromosome R,,,,,PHI:10642; PHI:10643; PHI:10645,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,phosphotransferase,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16850,PHI:10645,UniProt,Q59RR7,GenBank,AOW31442,,,SC5314,glk4,chromosome R,,,,,PHI:10642; PHI:10643; PHI:10644,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,phosphotransferase,,,glycolytic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32612591,PubMed,10.3389/fmicb.2020.01274,Front Microbiol. 2020 Jun 16;11:1274,patrick.vandijck@kuleuven.vib.be,A disrupted glycolytic pathway affects the adhesion capacity of C. albicans.,S Wijnants 2020,2020,4 genes,Wijnants-2020-Sugar Phosphorylation Controls C,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16851,PHI:10646,UniProt,I1RG07,GenBank,CEF74989,,,PH-1,Fgste2,chromosome 1,,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,coleoptile,pheromone-sensing G-protein-coupled receptor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32612109,PubMed,10.1038/s41598-020-67597-z,Sci Rep. 2020 Jul 1;10(1):10770,Michele.Loewen@nrc-cnrc.gc.ca,"Deletion of STE2 signifcantly decreased infection on germinating wheat coleoptiles, highlighting an association between Ste2, chemotropism and infection by F. graminearum.",P S Sridhar 2020,2020,1 gene,Sridhar-2020-Ste2 receptor-mediated chemotropi,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16852,PHI:10647,UniProt,Q02SF0,GenBank,ABJ13257,,,UCBPP-PA14,YbeY (PA14_12310),,,,YbeZ,UniProt: V6A9P6; GenBank: CDH75399,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,endoribonuclease,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16853,PHI:10648,UniProt,O52762,GenBank,AE004841_2,,,PAO1,katA,,,,,,PHI:10647,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,catalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16854,PHI:10647,UniProt,Q02SF0,GenBank,ABJ13257,,,UCBPP-PA14,YbeY (PA14_12310),,,,YbeZ,UniProt: V6A9P6; GenBank: CDH75399,PHI:10648,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,endoribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16855,PHI:10649,UniProt,P45684,GenBank,AE004782_8,,,PAO1,rpoS,,,,,,PHI:10647,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16856,PHI:10647,UniProt,Q02SF0,GenBank,ABJ13257,,,UCBPP-PA14,YbeY (PA14_12310),,,,YbeZ,UniProt: V6A9P6; GenBank: CDH75399,PHI:10649,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,endoribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16857,PHI:10650,UniProt,no data found,GenBank,,,,,reaL,,,,,,PHI:10647,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,small RNA,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16858,PHI:10647,UniProt,Q02SF0,GenBank,ABJ13257,,,UCBPP-PA14,YbeY (PA14_12310),,,,YbeZ,UniProt: V6A9P6; GenBank: CDH75399,PHI:10650,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,endoribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16859,PHI:10647,UniProt,Q02SF0,GenBank,ABJ13257,,,UCBPP-PA14,YbeY (PA14_12310),,,,YbeZ,UniProt: V6A9P6; GenBank: CDH75399,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,primates,9606,Homo sapiens (related: human),HL-60 cell line,,,neutrophil,endoribonuclease,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16860,PHI:10648,UniProt,O52762,GenBank,AE004841_2,,,PAO1,katA,,,,,,PHI:10647,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,primates,9606,Homo sapiens (related: human),HL-60 cell line,,,neutrophil,catalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16861,PHI:10647,UniProt,Q02SF0,GenBank,ABJ13257,,,UCBPP-PA14,YbeY (PA14_12310),,,,YbeZ,UniProt: V6A9P6; GenBank: CDH75399,PHI:10648,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,primates,9606,Homo sapiens (related: human),HL-60 cell line,,,neutrophil,endoribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16862,PHI:10649,UniProt,P45684,GenBank,AE004782_8,,,PAO1,rpoS,,,,,,PHI:10647,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,primates,9606,Homo sapiens (related: human),HL-60 cell line,,,neutrophil,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16863,PHI:10647,UniProt,Q02SF0,GenBank,ABJ13257,,,UCBPP-PA14,YbeY (PA14_12310),,,,YbeZ,UniProt: V6A9P6; GenBank: CDH75399,PHI:10649,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,primates,9606,Homo sapiens (related: human),HL-60 cell line,,,neutrophil,endoribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16864,PHI:10650,UniProt,no data found,GenBank,,,,,reaL,,,,,,PHI:10647,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,primates,9606,Homo sapiens (related: human),HL-60 cell line,,,neutrophil,small RNA,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16865,PHI:10647,UniProt,Q02SF0,GenBank,ABJ13257,,,UCBPP-PA14,YbeY (PA14_12310),,,,YbeZ,UniProt: V6A9P6; GenBank: CDH75399,PHI:10650,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,primates,9606,Homo sapiens (related: human),HL-60 cell line,,,neutrophil,endoribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32605982,PubMed,10.1128/mBio.00659-20,mBio. 2020 Jun 30;11(3):e00659-20,wuweihui@nankai.edu.cn,YbeY mutant was more susceptible to H2O2 and neutrophil-mediated killing.,Y Xia 2020,2020,4 genes,Xia-2020-Endoribonuclease YbeY Is Essential fo,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16866,PHI:10651,UniProt,Q8Y1L8,GenBank,CAD14202,,,GMI1000,RS01577,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Xinjinfeng 1,,,root; stem,hybrid sensor histidine kinase/response regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32599676,PubMed,10.1111/mpp.12963,Mol Plant Pathol. 2020 Aug;21(8):1099-1110,dayuleepong@163.com,Deletion of RS01577 resulted in a significant reduction in not only cell colonization but also pathogenicity in the host plants,F Shen 2020,2020,1 gene,Shen-2020-Ralstonia solanacearum promotes path,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16867,PHI:10652,UniProt,A0A1D8PNW2,GenBank,AOW29833,,,SC5314,mrv8,chromosome 5,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,primates,9606,Homo sapiens (related: human),TR146 cell line,,,TR-146 cell,four-pass transmembrane protein,,,,reduced virulence,,,,,,,,wild type,,no,caspofungin; cyclosporin A; fluconazole; amphotericin B; calcium chloride; calcofuor white,caspofungin: CHEBI:474180; cyclosporin A: CHEBI:4031; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; calcium chloride: CHEBI:3312; calcofuor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,32584995,PubMed,10.1093/femsyr/foaa033,FEMS Yeast Res. 2020 Aug 1;20(5):foaa033,duncan.wilson@exeter.ac.uk,"Deletion of MRV8 did not affect C. albicans adherence to, or initial invasion into human oral epithelia, but inhibited mycelial development and strongly reduced epithelial damage.",A C B P Costa 2020,2020,1 gene,"Costa-2020-Candida albicans Mrv8, is involved",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16868,PHI:10653,UniProt,Q5A5E0,GenBank,AOW30658,,,SC5314,dfr1,chromosome 7,PTETO-DFR1,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,dihydrofolate reductase,,,,reduced virulence,,,,,,,,reduced,,no,methotrexate; doxycycline,methotrexate: CHEBI:44185; doxycycline: CHEBI:50845,,,,,promoter mutation,,,YVS,32581079,PubMed,10.1128/mSphere.00374-20,mSphere. 2020 Jun 24;5(3):e00374-20,gpalmer5@uthsc.edu,The PTETO-DFR1 strain was rendered avirulent in a mouse model of disseminated candidiasis upon doxycycline treatment.,C DeJarnette 2020,2020,1 gene,DeJarnette-2020-Dihydrofolate Reductase Is a V,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16869,PHI:10654,UniProt,A0A0W0DPZ9,GenBank,KTA97333,,,2A,Elm1,,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,serine/threonine-protein kinase,,,,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,Congo red; calcofuor white; sodium dodecyl sulphate; calcium chloride,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulphate: CHEBI:8984; calcium chloride: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,32555245,PubMed,10.1038/s41598-020-66620-7,Sci Rep. 2020 Jun 17;10(1):9789,taiga-m@nagasaki-u.ac.jp,"Although the elm1Δ strain exhibited slower growth than the wild-type and ELM1-overexpression strains, as well as increased sensitivity to high temperature and cell-wall-damaging agents, it showed increased virulence in a Galleria mellonella-infection model.",Y Ito 2020,2020,1 gene,Ito-2020-Roles of Elm1 in antifungal susceptib,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16870,PHI:10654,UniProt,A0A0W0DPZ9,GenBank,KTA97333,,,2A,Elm1,,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen,serine/threonine-protein kinase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,Congo red; calcofuor white; sodium dodecyl sulphate; calcium chloride,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulphate: CHEBI:8984; calcium chloride: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,32555245,PubMed,10.1038/s41598-020-66620-7,Sci Rep. 2020 Jun 17;10(1):9789,taiga-m@nagasaki-u.ac.jp,"Although the elm1Δ strain exhibited slower growth than the wild-type and ELM1-overexpression strains, as well as increased sensitivity to high temperature and cell-wall-damaging agents, it showed increased virulence in a Galleria mellonella-infection model.",Y Ito 2020,2020,1 gene,Ito-2020-Roles of Elm1 in antifungal susceptib,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16871,PHI:10654,UniProt,A0A0W0DPZ9,GenBank,KTA97333,,,2A,Elm1,,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,serine/threonine-protein kinase,,,,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,Congo red; calcofuor white; sodium dodecyl sulphate; calcium chloride,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulphate: CHEBI:8984; calcium chloride: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,32555245,PubMed,10.1038/s41598-020-66620-7,Sci Rep. 2020 Jun 17;10(1):9789,taiga-m@nagasaki-u.ac.jp,"Although the elm1Δ strain exhibited slower growth than the wild-type and ELM1-overexpression strains, as well as increased sensitivity to high temperature and cell-wall-damaging agents, it showed increased virulence in a Galleria mellonella-infection model.",Y Ito 2020,2020,1 gene,Ito-2020-Roles of Elm1 in antifungal susceptib,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16872,PHI:10654,UniProt,A0A0W0DPZ9,GenBank,KTA97333,,,2A,Elm1,,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,serine/threonine-protein kinase,,,,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,Congo red; calcofuor white; sodium dodecyl sulphate; calcium chloride,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulphate: CHEBI:8984; calcium chloride: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,32555245,PubMed,10.1038/s41598-020-66620-7,Sci Rep. 2020 Jun 17;10(1):9789,taiga-m@nagasaki-u.ac.jp,The elm1Δ strain showed signifcantly higher adhesion to epithelial cells (A549 and Caco2 cells) as compared with the wild-type and ELM1-overexpression strains.,Y Ito 2020,2020,1 gene,Ito-2020-Roles of Elm1 in antifungal susceptib,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16873,PHI:10654,UniProt,A0A0W0DPZ9,GenBank,KTA97333,,,2A,Elm1,,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelial cell,serine/threonine-protein kinase,,,,increased virulence (hypervirulence),,,,,,,,reduced; aberrant,,no,Congo red; calcofuor white; sodium dodecyl sulphate; calcium chloride,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulphate: CHEBI:8984; calcium chloride: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,32555245,PubMed,10.1038/s41598-020-66620-7,Sci Rep. 2020 Jun 17;10(1):9789,taiga-m@nagasaki-u.ac.jp,The elm1Δ strain showed signifcantly higher adhesion to epithelial cells (A549 and Caco2 cells) as compared with the wild-type and ELM1-overexpression strains.,Y Ito 2020,2020,1 gene,Ito-2020-Roles of Elm1 in antifungal susceptib,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16874,PHI:10655,UniProt,no data found,GenBank,VUY44866,,,PAK,clpV3,chromosome 1,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cytoplasmic AAA+ ATPase protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32547522,PubMed,10.3389/fmicb.2020.01096,Front Microbiol. 2020 May 29;11:1096,Kangmin.Duan@umanitoba.ca,"An H3-T6SS deletion mutant PAO1(ΔclpV3) significantly affected the virulence-related phenotypes including pyocyanin production, biofilm formation, proteolytic activity, and motilities.",Y Li 2020,2020,1 gene,Li-2020-ClpV3 of the H3-Type VI Secretion Syst,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16875,PHI:10656,UniProt,G4NCI1,GenBank,EHA48278,,,70-15,hda1 (MGG_01076),chromosome 5,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdong,,,leaf,class II histone deacetylase,,,,reduced virulence,,,yes,,,reduced,,reduced,reduced,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32788890,PubMed,10.5423/PPJ.OA.06.2020.0099,Plant Pathol J.2020 Aug 1;36(4):314-322,jjeon@yu.ac.kr,MoHDA1-dependent histone deacetylation was important for effcient asexual development and infection of host plants in M. oryzae.,T Kim 2020,2020,1 gene,"Kim-2020-A Histone Deacetylase, MoHDA1 Regulat",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16876,PHI:10657,UniProt,A0A063BP02,GenBank,KDB12146,,,UV-8b,UvAtg8,,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,leaf,microtubule-associated protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,wild type,no,H2O2; NaCl; sorbitol; SDS; calcofluor white; Congo red,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32785866,PubMed,10.1186/s12284-020-00418-z,Rice (N Y).2020 Aug 12;13(1):56,kouyanjun241@hotmail.com,"ΔUvatg8 mutant was defective in the vegetative growth, conidiation, adaption to oxidative, hyperosmotic, cell wall stresses, and production of toxic compounds.",S Meng 2020,2020,1 gene,Meng-2020-UvAtg8-Mediated Autophagy Regulates,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16877,PHI:10658,UniProt,A0A384J8J3,GenBank,ATZ46936,,,B05.10,BcFET1 (Bcin02g02780),BCIN02,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Venus,,,leaf,ferroxidase,,,,increased virulence (hypervirulence),,,,,,,reduced,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32753496,PubMed,10.1128/mBio.01379-20,mBio.2020 Aug 4;11(4):e01379-20,paulo.canessa@unab.cl,"The bcfet1 mutant displayed delayed conidiation, iron-dependent sclerotium production, and significantly reduced whole-cell iron content.",E Vasquez-Montano 2020,2020,1 gene,Vasquez-Montaño-2020-Defects in the Ferroxidas,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16878,PHI:10658,UniProt,A0A384J8J3,GenBank,ATZ46936,,,B05.10,BcFET1 (Bcin02g02780),BCIN02,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,ferroxidase,,,,increased virulence (hypervirulence),,,,,,,reduced,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32753496,PubMed,10.1128/mBio.01379-20,mBio.2020 Aug 4;11(4):e01379-20,paulo.canessa@unab.cl,"The bcfet1 mutant displayed delayed conidiation, iron-dependent sclerotium production, and significantly reduced whole-cell iron content.",E Vasquez-Montano 2020,2020,1 gene,Vasquez-Montaño-2020-Defects in the Ferroxidas,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16879,PHI:10659,UniProt,G4ZRT3,GenBank,EGZ13970,,,P6497,PsGH7a,,,,,,,67593,Phytophthora sojae,1094619,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,hypocotyl; leaf,conserved glycoside hydrolase family 7 cellobiohydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32714289,PubMed,10.3389/fmicb.2020.01285,Front Microbiol.2020 Jul 2;11:1285,wangqunqing@163.com,PsGH7a is an elicitor and induced hypersensitive responses in various plants.,X Tan 2020,2020,1 gene,Tan-2020-A Conserved Glycoside Hydrolase Famil,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16880,PHI:10660,,no data found,,,,,,ESX-1,,,,,,,1781,Mycobacterium marinum,1348799,M,opportunistic infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,ESX-1 secretion-associated protein EspB,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32701962,PubMed,10.1371/journal.pone.0233252,PLoS One.2020 Jul 23;15(7):e0233252,lr404@cam.ac.uk,Phthiocerol dimycocerosate (PDIM) enhanced the membrane disrupting activity of pathogenic mycobacteria and indicates that the role they play in damaging phagosomal and red blood cell membranes may differ.,M M Osman 2020,2020,2 genes,Osman-2020-Mycobacterium marinum phthiocerol d,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16881,PHI:10661,UniProt,B2HIL9,GenBank,ACC40213,,,M,mmpL7,,,,,,,1781,Mycobacterium marinum,1348799,M,opportunistic infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,conserved transmembrane transport protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32701962,PubMed,10.1371/journal.pone.0233252,PLoS One.2020 Jul 23;15(7):e0233252,lr404@cam.ac.uk,Phthiocerol dimycocerosate (PDIM) enhanced the membrane disrupting activity of pathogenic mycobacteria and indicates that the role they play in damaging phagosomal and red blood cell membranes may differ.,M M Osman 2020,2020,2 genes,Osman-2020-Mycobacterium marinum phthiocerol d,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16882,PHI:10660,,no data found,,,,,,ESX-1,,,,,,,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESX-1 secretion-associated protein EspB,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32701962,PubMed,10.1371/journal.pone.0233252,PLoS One.2020 Jul 23;15(7):e0233252,lr404@cam.ac.uk,Phthiocerol dimycocerosate (PDIM) enhanced the membrane disrupting activity of pathogenic mycobacteria and indicates that the role they play in damaging phagosomal and red blood cell membranes may differ.,M M Osman 2020,2020,2 genes,Osman-2020-Mycobacterium marinum phthiocerol d,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16883,PHI:10661,UniProt,B2HIL9,GenBank,ACC40213,,,M,mmpL7,,,,,,,1781,Mycobacterium marinum,1348799,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,conserved transmembrane transport protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32701962,PubMed,10.1371/journal.pone.0233252,PLoS One.2020 Jul 23;15(7):e0233252,lr404@cam.ac.uk,Phthiocerol dimycocerosate (PDIM) enhanced the membrane disrupting activity of pathogenic mycobacteria and indicates that the role they play in damaging phagosomal and red blood cell membranes may differ.,M M Osman 2020,2020,2 genes,Osman-2020-Mycobacterium marinum phthiocerol d,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16884,PHI:10662,UniProt,Q8XPQ7,GenBank,CAD18732,,,GMI1000,katE,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Marmande,,,leaf,catalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32849714,PubMed,10.3389/fpls.2020.01156,Front Plant Sci. 2020 Jul 31;11:1156,orellano@ibr-conicet.gov.ar,"No statistical differences were observed in wilting symptoms in plants inoculated with the wild type, the katE disruption mutant or the complemented strain.",M L Tondo 2020,2020,1 gene,Tondo-2020-KatE From the Bacterial Plant Patho,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16885,PHI:10663,UniProt,A0A0H2ZEY4,GenBank,ABJ13052,,,UCBPP-PA14,oprC,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,outer membrane copper receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32849593,PubMed,10.3389/fimmu.2020.01696,Front Immunol. 2020; 11: 1696,lianghh@nwu.edu.cn,OprC deficiency significantly alleviated pyroptosis in macrophages.,P Gao 2020,2020,1 gene,Gao-2020-oprC Impairs Host Defense by Increasi,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16886,PHI:10664,,no data found,,,,,,Avr7,,,,,,,5022,Leptosphaeria maculans,,DS103,blackleg (rapeseed),eudicots,3708,Brassica napus (related: rape),cv. 01-23-2-1; cv. Westar,,,seedling,avirulence gene,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,32849487,PubMed,10.3389/fmicb.2020.01969,Front Microbiol. 2020; 11: 1969,Dilantha.Fernando@umanitoba.ca,The Δumavr7 mutant isolate produced large gray/green lesions on cotyledons.,Z Zou 2020,2020,1 gene,Zou-2020-Generation and Characterization of a,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16887,PHI:10665,UniProt,A0A384JGZ2,GenBank,ATZ49859,,,B05.10,RPD3 (Bcin05g02590),BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,histone deacetylase,,,,reduced virulence,,,,,,wild type,,reduced,reduced,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32849432,PubMed,10.3389/fmicb.2020.01832,Front Microbiol. 2020; 11: 1832.,wliang1@qau.edu.cn,"The BcRPD3 overexpression strains showed slightly delayed vegetative growth, dramatically impaired infection structure formation, oxidative stress response, and virulence.",N Zhang 2020,2020,1 gene,Zhang-2020-BcRPD3-Mediated Histone Deacetylati,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16888,PHI:10666,UniProt,A0A1C3YHM4,GenBank,SCB64083,,,PH-1,VPS9 (FGRAMPH1_01G01477),chromosome 1,,,FgRab51; FgRab52,UniProt: A0A098DVM4; GenBank: CEF85885; UniProt: A0A1C3YHW1; GenBank: SCB64102,,5518,Fusarium graminearum,229533,PH-1,scab (wheat),monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,Rab5 guanine nucleotide exchange factor,,,DON biosynthesis,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32849361,PubMed,10.3389/fmicb.2020.01714,Front Microbiol. 2020; 11: 1714,jiezhou@fafu.edu.cn,"Deletion of FgVPS9 resulted in impaired vegetative growth, conidiation, and autophagy, as well as defects in endocytosis, DON biosynthesis, and plant infection in F. graminearum.",C Yang 2020,2020,1 gene,"Yang-2020-FgVps9, a Rab5 GEF, Is Critical for",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16889,PHI:10667,,no data found,,,,,,bspP (BGLU_RS28885),,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Milyang 23,,,leaf sheath,"protein containing PDC2, PAS-9, SpoIIE, and HATPase domains",,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32833990,PubMed,10.1371/journal.pone.0238151,PLoS One. 2020 Aug 24;15(8):e0238151,ingyu@snu.ac.kr,The bspP null mutant was less virulent and exhibited less effective colonization of rice lants than the wild type.,G Y Kwak 2020,2020,1 gene,Kwak-2020-Adverse effects of adaptive mutation,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16890,PHI:10668,UniProt,A0A6C8TBQ7,GenBank,KAE9675871,,,TzEc076,norV,,,,,,PHI:10669,562,Escherichia coli,1078030,serotype O91:H21 strain B2F1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon,anaerobic nitric oxide reductase flavorubredoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32825770,PubMed,10.3390/pathogens9090683,"Pathogens 2020, 9(9), 683",gardette.marion@gmail.com,"The deletion of norVW in the strain O91:H21 B2F1 had no impact on its virulence, whereas it reduced the ability of the strain O157:H7 620 to persist in the mouse gut.",M Gardette 2020,2020,2 genes,Gardette-2020-Role of the Nitric Oxide Reducta,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16891,PHI:10669,UniProt,P37596,GenBank,BAA05934,,,TzEc076,norW,,,,,,PHI:10668,562,Escherichia coli,1078030,serotype O91:H21 strain B2F1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon,NO reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32825770,PubMed,10.3390/pathogens9090683,"Pathogens 2020, 9(9), 683",gardette.marion@gmail.com,"The deletion of norVW in the strain O91:H21 B2F1 had no impact on its virulence, whereas it reduced the ability of the strain O157:H7 620 to persist in the mouse gut.",M Gardette 2020,2020,2 genes,Gardette-2020-Role of the Nitric Oxide Reducta,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16892,PHI:10668,UniProt,A0A6C8TBQ7,GenBank,KAE9675871,,,TzEc076,norV,,,,,,PHI:10669,562,Escherichia coli,,serotype O157:H7 strain 620,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon,anaerobic nitric oxide reductase flavorubredoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32825770,PubMed,10.3390/pathogens9090683,"Pathogens 2020, 9(9), 683",gardette.marion@gmail.com,"The deletion of norVW in the strain O91:H21 B2F1 had no impact on its virulence, whereas it reduced the ability of the strain O157:H7 620 to persist in the mouse gut.",M Gardette 2020,2020,2 genes,Gardette-2020-Role of the Nitric Oxide Reducta,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16893,PHI:10669,UniProt,P37596,GenBank,BAA05934,,,TzEc076,norW,,,,,,PHI:10668,562,Escherichia coli,,serotype O157:H7 strain 620,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon,NO reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32825770,PubMed,10.3390/pathogens9090683,"Pathogens 2020, 9(9), 683",gardette.marion@gmail.com,"The deletion of norVW in the strain O91:H21 B2F1 had no impact on its virulence, whereas it reduced the ability of the strain O157:H7 620 to persist in the mouse gut.",M Gardette 2020,2020,2 genes,Gardette-2020-Role of the Nitric Oxide Reducta,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16894,PHI:10670,,no data found,GenBank,CAZ50822,,,SC84,comR (SSUSC84_0046),,,,,,,1307,Streptococcus suis,,SC-19,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood,transcriptional regulator helix-turn-helix domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32825733,PubMed,10.3390/genes11090972,"Genes 2020, 11(9), 972",jinmeilin@mail.hzau.edu.cn,"The survival and pro-inflammatory abilities of ΔcomR, ΔsitR, and ΔsxvR mutant strains in blood was significantly reduced.",l Liu 2020,2020,3 genes,Liu-2020-Screening of Virulence-Related Transc,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16895,PHI:10671,,no data found,GenBank,CAZ51651,,,SC84,sitR (SSUSC84_0874),,,,,,,1307,Streptococcus suis,,SC-19,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood,abortive infection system Abi protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32825733,PubMed,10.3390/genes11090972,"Genes 2020, 11(9), 972",jinmeilin@mail.hzau.edu.cn,"The survival and pro-inflammatory abilities of ΔcomR, ΔsitR, and ΔsxvR mutant strains in blood was significantly reduced.",l Liu 2020,2020,3 genes,Liu-2020-Screening of Virulence-Related Transc,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16896,PHI:10672,,no data found,GenBank,CAZ52563,,,SC84,sxvR (SSUSC84_1787),,,,,,,1307,Streptococcus suis,,SC-19,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood,putative transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32825733,PubMed,10.3390/genes11090972,"Genes 2020, 11(9), 972",jinmeilin@mail.hzau.edu.cn,"The survival and pro-inflammatory abilities of ΔcomR, ΔsitR, and ΔsxvR mutant strains in blood was significantly reduced.",l Liu 2020,2020,3 genes,Liu-2020-Screening of Virulence-Related Transc,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16897,PHI:10673,,no data found,GenBank,QNQ74175,,,,pgc4,,,,,,,5507,Fusarium oxysporum,61366,f. sp. cubense race 4,vascular wilt,monocots,4641,Musa acuminata (related: dwarf banana),cv. Guangfen-1,,,leaf,exo-polygalacturonase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32824317,PubMed,10.3390/ijms21165886,"Int. J. Mol. Sci. 2020, 21, 5886",08luomei@163.com,"Foc4Δpgc4 mutant strain showed a lower aerial hyphal growth, grew slower, and had a reduced virulence.",Z Dong 2020,2020,1 gene,Dong-2020-An Exo-Polygalacturonase Pgc4 Regula,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16898,PHI:10673,,no data found,GenBank,QNQ74175,,,,pgc4,,,,,,,5507,Fusarium oxysporum,61366,f. sp. cubense race 4,vascular wilt,monocots,4641,Musa acuminata (related: dwarf banana),cv. Baxi,,,leaf,exo-polygalacturonase,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32824317,PubMed,10.3390/ijms21165886,"Int. J. Mol. Sci. 2020, 21, 5886",08luomei@163.com,"Foc4Δpgc4 mutant strain showed a lower aerial hyphal growth, grew slower, and had a reduced virulence.",Z Dong 2020,2020,1 gene,Dong-2020-An Exo-Polygalacturonase Pgc4 Regula,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16899,PHI:10674,UniProt,P0CE18,GenBank,CAA29894,,,L1/440/LN,Pgp3,,,,,,,813,Chlamydia trachomatis,272561,D/UW-3/CX,sexually transmitted disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,urogenital system,plasmid gene protein 3,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32817110,PubMed,10.1128/mBio.01902-20,mBio.2020 Aug 18;11(4):e01902-20. doi: 10.1128/mBio.01902-20,hcaldwell@niaid.nih.gov,"Mice infected with CtD pgp3–, CtD pgp4–, and CtD pgp3– pgp4– strains showed no or minimal uterine horn dilation.",C Yang 2020,2020,2 genes,Yang-2020-Chlamydia trachomatis Plasmid Gene P,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16900,PHI:10675,UniProt,P0CE23,GenBank,CAB41600,,,L1/440/LN,Pgp4,,,,,,,813,Chlamydia trachomatis,272561,D/UW-3/CX,sexually transmitted disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,urogenital system,plasmid gene protein 4,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32817110,PubMed,10.1128/mBio.01902-20,mBio.2020 Aug 18;11(4):e01902-20. doi: 10.1128/mBio.01902-20,hcaldwell@niaid.nih.gov,"Mice infected with CtD pgp3–, CtD pgp4–, and CtD pgp3– pgp4– strains showed no or minimal uterine horn dilation.",C Yang 2020,2020,2 genes,Yang-2020-Chlamydia trachomatis Plasmid Gene P,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16901,PHI:10674,UniProt,P0CE18,GenBank,CAA29894,,,L1/440/LN,Pgp3,,,,,,,813,Chlamydia trachomatis,580047,A2497,sexually transmitted disease,primates,9541,Macaca fascicularis (related: crab-eating macaque),,,,eye,plasmid gene protein 3,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32817110,PubMed,10.1128/mBio.01902-20,mBio.2020 Aug 18;11(4):e01902-20. doi: 10.1128/mBio.01902-20,hcaldwell@niaid.nih.gov,A C. trachomatis Pgp3 null ocular strain did not produce persistent infection in nonhuman primates.,C Yang 2020,2020,2 genes,Yang-2020-Chlamydia trachomatis Plasmid Gene P,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16902,PHI:10676,UniProt,A0A559L303,GenBank,TVY67095,,,160527,Sge1,,,,,,,5507,Fusarium oxysporum,1229664,f. sp. cubense race 1,wilt,monocots,4641,Musa acuminata (related: dwarf banana),cv. Rasthali,,,corm,global transcription regulator,,,,reduced virulence,,,,,,reduced,,wild type,,no,glycerol; sorbitol; sodium chloride; potassium chloride; sodium nitrite; Congo red; calcofluor white; hydrogen peroxide; menadione,glycerol: CHEBI:17754; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; potassium chloride: CHEBI:32588; sodium nitrite: CHEBI:78870; Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,32795268,PubMed,10.1186/s12866-020-01936-y,BMC Microbiol. 2020 Aug 14;20(1):255. doi: 10.1186/s12866-020-01936-y,siddhesh.ghag@cbs.ac.in,"The deletion mutant, FocSge1 displayed poor conidial count, loss of hydrophobicity, reduced pigmentation, decrease in fusaric acid production and pathogenicity.",V Gurdaswani 2020,2020,1 gene,Gurdaswani-2020-FocSge1 in Fusarium oxysporum,BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16903,PHI:10677,UniProt,Q9LBD5,GenBank,AAF61278,,,PXO86,Hpa2,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16904,PHI:10678,UniProt,Q6QJ83,GenBank,QIE14262,,,IXO1088,HrpF,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,serine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16905,PHI:10679,UniProt,K4LAY3,GenBank,AFV08857,,,ITCC BB0001,XopN,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16906,PHI:10680,UniProt,Q9K2U6,GenBank,AF320050_5,,,13751,hrcV,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16907,PHI:10681,UniProt,B2SU53,GenBank,ACD58243,,,PXO99A,PthXo1,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16908,PHI:10681,UniProt,B2SU53,GenBank,ACD58243,,,PXO99A,PthXo1,,,,,,PHI:10677,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16909,PHI:10677,UniProt,Q9LBD5,GenBank,AAF61278,,,PXO86,Hpa2,,,,,,PHI:10681,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16910,PHI:10681,UniProt,B2SU53,GenBank,ACD58243,,,PXO99A,PthXo1,,,,,,PHI:10679,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16911,PHI:10679,UniProt,K4LAY3,GenBank,AFV08857,,,ITCC BB0001,XopN,,,,,,PHI:10681,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16912,PHI:10681,UniProt,B2SU53,GenBank,ACD58243,,,PXO99A,PthXo1,,,,,,PHI:10678,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16913,PHI:10678,UniProt,Q6QJ83,GenBank,QIE14262,,,IXO1088,HrpF,,,,,,PHI:10681,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,serine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793141,PubMed,10.3389/fmicb.2020.01601,Front Microbiol.2020 Jul 22;11:1601. doi: 10.3389/fmicb.2020.01601. eCollection 2020,chenlei@sdau.edu.cn,"The three translocators (Hpa2, HrpF, and XopN) synergistically promote PthXo1 to perform its virulent role.",X Mo 2020,2020,5 genes,"Mo-2020-Three Proteins (Hpa2, HrpF and XopN) A",BATCH_102A,2020-09-01,MC,,,,,,,,,,,,,
,,Record 16914,PHI:10682,UniProt,Q8XY07,GenBank,CAD15658,,,GMI1000,murI,,,,,,,305,Ralstonia solanacearum,,SL341,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker; cv. Hawaii 7996,,,root; leaf,glutamate racemase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32788894,PubMed,10.5423/PPJ.OA.03.2020.0049,Plant Pathol J. 2020 Aug 1;36(4):355-363. doi: 10.5423/PPJ.OA.03.2020.0049,seonlee@dau.ac.kr,"The mutant strain lost its motility, and its virulence in the tomato plant was markedly diminished compared to that of the wild type.",K Choi 2020,2020,1 gene,Choi-2020-Contribution of the murI Gene Encodi,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16915,PHI:10683,UniProt,G8HWS9,GenBank,AEX09623,,,CN3718,agrB,,,,,,,1502,Clostridium perfringens,,ATCC 3624,intestinal disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skeletal muscle,membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32554714,PubMed,10.1128/mSphere.00500-20,mSphere. 2020 Jun 17;5(3):e00500-20,fauzal@ucdavis.edu,An agrB-null mutant strain produced significantly less severe changes in the skeletal muscle of challenged mice.,M A Navarro 2020,2020,1 gene,Navarro-2020-The Agr-Like Quorum-Sensing Syste,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16916,PHI:10684,UniProt,E9EN82,GenBank,EFZ03708,,,ARSEF 23,MrHex1 (MAA_00782),,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,wing,woronin body major protein,,,,reduced virulence,,yes,yes,,,reduced,,reduced,,no,SDS; KCl; sorbitol; farnesol; calcofluor white; Congo red,SDS: CHEBI:8984; KCl: CHEBI:32588; sorbitol: CHEBI:30911; farnesol: CHEBI:28600; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32937856,PubMed,10.3390/jof6030172,J Fungi (Basel). 2020 Sep 14;6(3):E172. doi: 10.3390/jof6030172,wangcs@sippe.ac.cn,Woronin body major protein,G Tang 2020,2020,1 gene,Tang-2020-MrHex1 is Required for Woronin Body,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16917,PHI:10684,UniProt,E9EN82,GenBank,EFZ03708,,,ARSEF 23,MrHex1 (MAA_00782),,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,woronin body major protein,,,,reduced virulence,,yes,yes,,,reduced,,reduced,,no,SDS; KCl; sorbitol; farnesol; calcofluor white; Congo red,SDS: CHEBI:8984; KCl: CHEBI:32588; sorbitol: CHEBI:30911; farnesol: CHEBI:28600; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32937856,PubMed,10.3390/jof6030172,J Fungi (Basel). 2020 Sep 14;6(3):E172. doi: 10.3390/jof6030172,wangcs@sippe.ac.cn,Woronin body major protein,G Tang 2020,2020,1 gene,Tang-2020-MrHex1 is Required for Woronin Body,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16918,PHI:10684,UniProt,E9EN82,GenBank,EFZ03708,,,ARSEF 23,MrHex1 (MAA_00782),,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,woronin body major protein,,,,reduced virulence,,yes,yes,,,reduced,,reduced,,no,SDS; KCl; sorbitol; farnesol; calcofluor white; Congo red,SDS: CHEBI:8984; KCl: CHEBI:32588; sorbitol: CHEBI:30911; farnesol: CHEBI:28600; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32937856,PubMed,10.3390/jof6030172,J Fungi (Basel). 2020 Sep 14;6(3):E172. doi: 10.3390/jof6030172,wangcs@sippe.ac.cn,Woronin body major protein,G Tang 2020,2020,1 gene,Tang-2020-MrHex1 is Required for Woronin Body,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16919,PHI:10685,UniProt,A4D9V5,GenBank,EBA27302,,,Af293,shoA (Afu2g00660),chromosome 2,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"sensor histidine kinase/response regulator, putative",,,,reduced virulence,,,,,,,,reduced,,no,CaCl2; menadione; caspofungin; sorbitol; calcofluor white; Congo red,CaCl2: CHEBI:3312; menadione: CHEBI:28869; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32938702,PubMed,10.1128/mSphere.00818-20,mSphere. 2020 Sep 16;5(5):e00818-20. doi: 10.1128/mSphere.00818-20,ggoldman@usp.br,"The shoA, msbA, and opyA singly and doubly null mutants are important for the cell wall integrity (CWI) pathway, oxidative stress, and virulence as assessed by a Galleria mellonella model.",L P Silva 2020,2020,3 genes,Silva-2020-Putative Membrane Receptors Contrib,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16920,PHI:10686,UniProt,Q4W9Q8,GenBank,EAL84555,,,Af293,msbA (Afu4g04070),chromosome 4,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"mucin family signaling protein, putative",,,,reduced virulence,,,,,,,,reduced,,no,CaCl2; menadione; caspofungin; sorbitol; calcofluor white; Congo red,CaCl2: CHEBI:3312; menadione: CHEBI:28869; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32938702,PubMed,10.1128/mSphere.00818-20,mSphere. 2020 Sep 16;5(5):e00818-20. doi: 10.1128/mSphere.00818-20,ggoldman@usp.br,"The shoA, msbA, and opyA singly and doubly null mutants are important for the cell wall integrity (CWI) pathway, oxidative stress, and virulence as assessed by a Galleria mellonella model.",L P Silva 2020,2020,3 genes,Silva-2020-Putative Membrane Receptors Contrib,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16921,PHI:10687,UniProt,Q4WYV6,GenBank,EAL92147,,,Af293,opyA (Afu3g14410),chromosome 3,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,conserved hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,CaCl2; menadione; caspofungin; sorbitol; calcofluor white; Congo red,CaCl2: CHEBI:3312; menadione: CHEBI:28869; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32938702,PubMed,10.1128/mSphere.00818-20,mSphere. 2020 Sep 16;5(5):e00818-20. doi: 10.1128/mSphere.00818-20,ggoldman@usp.br,"The shoA, msbA, and opyA singly and doubly null mutants are important for the cell wall integrity (CWI) pathway, oxidative stress, and virulence as assessed by a Galleria mellonella model.",L P Silva 2020,2020,3 genes,Silva-2020-Putative Membrane Receptors Contrib,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16922,PHI:10685,UniProt,A4D9V5,GenBank,EBA27302,,,Af293,shoA (Afu2g00660),chromosome 2,,,,,PHI:10686,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"sensor histidine kinase/response regulator, putative",,,,reduced virulence,,,,,,,,reduced,,no,CaCl2; menadione; caspofungin; sorbitol; calcofluor white; Congo red,CaCl2: CHEBI:3312; menadione: CHEBI:28869; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32938702,PubMed,10.1128/mSphere.00818-20,mSphere. 2020 Sep 16;5(5):e00818-20. doi: 10.1128/mSphere.00818-20,ggoldman@usp.br,"The shoA, msbA, and opyA singly and doubly null mutants are important for the cell wall integrity (CWI) pathway, oxidative stress, and virulence as assessed by a Galleria mellonella model.",L P Silva 2020,2020,3 genes,Silva-2020-Putative Membrane Receptors Contrib,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16923,PHI:10686,UniProt,Q4W9Q8,GenBank,EAL84555,,,Af293,msbA (Afu4g04070),chromosome 4,,,,,PHI:10685,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"mucin family signaling protein, putative",,,,reduced virulence,,,,,,,,reduced,,no,CaCl2; menadione; caspofungin; sorbitol; calcofluor white; Congo red,CaCl2: CHEBI:3312; menadione: CHEBI:28869; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32938702,PubMed,10.1128/mSphere.00818-20,mSphere. 2020 Sep 16;5(5):e00818-20. doi: 10.1128/mSphere.00818-20,ggoldman@usp.br,"The shoA, msbA, and opyA singly and doubly null mutants are important for the cell wall integrity (CWI) pathway, oxidative stress, and virulence as assessed by a Galleria mellonella model.",L P Silva 2020,2020,3 genes,Silva-2020-Putative Membrane Receptors Contrib,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16924,PHI:10685,UniProt,A4D9V5,GenBank,EBA27302,,,Af293,shoA (Afu2g00660),chromosome 2,,,,,PHI:10687,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"sensor histidine kinase/response regulator, putative",,,,reduced virulence,,,,,,,,reduced,,no,CaCl2; menadione; caspofungin; sorbitol; calcofluor white; Congo red,CaCl2: CHEBI:3312; menadione: CHEBI:28869; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32938702,PubMed,10.1128/mSphere.00818-20,mSphere. 2020 Sep 16;5(5):e00818-20. doi: 10.1128/mSphere.00818-20,ggoldman@usp.br,"The shoA, msbA, and opyA singly and doubly null mutants are important for the cell wall integrity (CWI) pathway, oxidative stress, and virulence as assessed by a Galleria mellonella model.",L P Silva 2020,2020,3 genes,Silva-2020-Putative Membrane Receptors Contrib,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16925,PHI:10687,UniProt,Q4WYV6,GenBank,EAL92147,,,Af293,opyA (Afu3g14410),chromosome 3,,,,,PHI:10685,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,conserved hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,CaCl2; menadione; caspofungin; sorbitol; calcofluor white; Congo red,CaCl2: CHEBI:3312; menadione: CHEBI:28869; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32938702,PubMed,10.1128/mSphere.00818-20,mSphere. 2020 Sep 16;5(5):e00818-20. doi: 10.1128/mSphere.00818-20,ggoldman@usp.br,"The shoA, msbA, and opyA singly and doubly null mutants are important for the cell wall integrity (CWI) pathway, oxidative stress, and virulence as assessed by a Galleria mellonella model.",L P Silva 2020,2020,3 genes,Silva-2020-Putative Membrane Receptors Contrib,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16926,PHI:10686,UniProt,Q4W9Q8,GenBank,EAL84555,,,Af293,msbA (Afu4g04070),chromosome 4,,,,,PHI:10687,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"mucin family signaling protein, putative",,,,reduced virulence,,,,,,,,reduced,,no,CaCl2; menadione; caspofungin; sorbitol; calcofluor white; Congo red,CaCl2: CHEBI:3312; menadione: CHEBI:28869; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32938702,PubMed,10.1128/mSphere.00818-20,mSphere. 2020 Sep 16;5(5):e00818-20. doi: 10.1128/mSphere.00818-20,ggoldman@usp.br,"The shoA, msbA, and opyA singly and doubly null mutants are important for the cell wall integrity (CWI) pathway, oxidative stress, and virulence as assessed by a Galleria mellonella model.",L P Silva 2020,2020,3 genes,Silva-2020-Putative Membrane Receptors Contrib,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16927,PHI:10687,UniProt,Q4WYV6,GenBank,EAL92147,,,Af293,opyA (Afu3g14410),chromosome 3,,,,,PHI:10686,746128,Aspergillus fumigatus,1266464,CEA17,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,conserved hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,CaCl2; menadione; caspofungin; sorbitol; calcofluor white; Congo red,CaCl2: CHEBI:3312; menadione: CHEBI:28869; caspofungin: CHEBI:474180; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32938702,PubMed,10.1128/mSphere.00818-20,mSphere. 2020 Sep 16;5(5):e00818-20. doi: 10.1128/mSphere.00818-20,ggoldman@usp.br,"The shoA, msbA, and opyA singly and doubly null mutants are important for the cell wall integrity (CWI) pathway, oxidative stress, and virulence as assessed by a Galleria mellonella model.",L P Silva 2020,2020,3 genes,Silva-2020-Putative Membrane Receptors Contrib,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16928,PHI:10688,UniProt,J9VY90,GenBank,AFR96690,,,H99,lac1,chromosome 8,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),,,,macrophage,laccase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32900810,PubMed,10.1128/mBio.02085-20,mBio. 2020 Sep 8;11(5):e02085-20. doi: 10.1128/mBio.02085-20,palbuquerque@unb.br,Fungi lacking Lac1 enzyme are nonlytically exocytosed less often and the process was independent of melanin production.,S O Frazão 2020,2020,1 gene,Frazão-2020-Laccase Affects the Rate of Crypto,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16929,PHI:10689,,no data found,GenBank,AWB40297,,,12567,ciaD,,,,,,,197,Campylobacter jejuni,1408176,F38011,gastroenteritis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,intestine,invasion antigen D,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32887530,PubMed,10.1080/19490976.2020.1814121,Gut Microbes. 2020 Nov 9;12(1):1-25. doi: 10.1080/19490976.2020.1814121,konkel@wsu.edu,"Infection with the noninvasive C. jejuni ΔciaD mutant resulted in a blunted infammatory response, with less infammatory cytokines and neutrophil markers.",N M Negretti 2020,2020,1 gene,Negretti-2020-A porcine ligated loop model rev,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16930,PHI:10690,UniProt,I1RWD1,GenBank,CEF76973,,,PH-1,FgDnfA (FGSG_08595),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; coleoptile,"phospholipid-transporting ATPase, flippase",,,DON biosynthesis,reduced virulence,,,,,,reduced; aberrant,reduced; aberrant,reduced,reduced,no,SDS; NaCl; calcofluor white; Congo red,SDS: CHEBI:8984; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32881238,PubMed,10.1111/mpp.12985,Mol Plant Pathol. 2020 Sep 2;21(10):1307-21. doi: 10.1111/mpp.12985. Online ahead of print,wenhuiz@fafu.edu.cn,"FgDnfB and FgDnfD had redundant functions in the regulation of phosphatidylcholine transport, and double deletion of FgDNFB and FgDNFD showed serious defects in fungal development, DON synthesis, and virulence.",Y Yun 2020,2020,5 genes,Yun-2020-Flippases play specific but distinct,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16931,PHI:10691,UniProt,I1RMF9,GenBank,CEF87437,,,PH-1,FgDnfD (FGSG_05149),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; coleoptile,"phospholipid-transporting ATPase, flippase",,,DON biosynthesis,reduced virulence,,,,,,reduced; aberrant,reduced; aberrant,wild type,,no,SDS; NaCl; calcofluor white; Congo red,SDS: CHEBI:8984; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32881238,PubMed,10.1111/mpp.12985,Mol Plant Pathol. 2020 Sep 2;21(10):1307-21. doi: 10.1111/mpp.12985. Online ahead of print,wenhuiz@fafu.edu.cn,"FgDnfB and FgDnfD had redundant functions in the regulation of phosphatidylcholine transport, and double deletion of FgDNFB and FgDNFD showed serious defects in fungal development, DON synthesis, and virulence.",Y Yun 2020,2020,5 genes,Yun-2020-Flippases play specific but distinct,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16932,PHI:10692,UniProt,I1RRL4,GenBank,CEF84829,,,PH-1,FgDnfB (FGSG_06743),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; coleoptile,"phospholipid-transporting ATPase, flippase",,,DON biosynthesis,unaffected pathogenicity,,,,,,reduced; aberrant,reduced; aberrant,wild type,,no,SDS; NaCl; calcofluor white; Congo red,SDS: CHEBI:8984; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32881238,PubMed,10.1111/mpp.12985,Mol Plant Pathol. 2020 Sep 2;21(10):1307-21. doi: 10.1111/mpp.12985. Online ahead of print,wenhuiz@fafu.edu.cn,"FgDnfB and FgDnfD had redundant functions in the regulation of phosphatidylcholine transport, and double deletion of FgDNFB and FgDNFD showed serious defects in fungal development, DON synthesis, and virulence.",Y Yun 2020,2020,5 genes,Yun-2020-Flippases play specific but distinct,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16933,PHI:10693,UniProt,I1RXF4,GenBank,CEF83308,,,PH-1,FgDnfC1 (FGSG_09020),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; coleoptile,"phospholipid-transporting ATPase, flippase",,,DON biosynthesis,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,SDS; NaCl; calcofluor white; Congo red,SDS: CHEBI:8984; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32881238,PubMed,10.1111/mpp.12985,Mol Plant Pathol. 2020 Sep 2;21(10):1307-21. doi: 10.1111/mpp.12985. Online ahead of print,wenhuiz@fafu.edu.cn,"FgDnfB and FgDnfD had redundant functions in the regulation of phosphatidylcholine transport, and double deletion of FgDNFB and FgDNFD showed serious defects in fungal development, DON synthesis, and virulence.",Y Yun 2020,2020,5 genes,Yun-2020-Flippases play specific but distinct,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16934,PHI:10694,UniProt,I1RAR0,GenBank,CEF72557,,,PH-1,FgDnfC2 (FGSG_00595),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; coleoptile,"phospholipid-transporting ATPase, flippase",,,DON biosynthesis,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,SDS; NaCl; calcofluor white; Congo red,SDS: CHEBI:8984; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32881238,PubMed,10.1111/mpp.12985,Mol Plant Pathol. 2020 Sep 2;21(10):1307-21. doi: 10.1111/mpp.12985. Online ahead of print,wenhuiz@fafu.edu.cn,"FgDnfB and FgDnfD had redundant functions in the regulation of phosphatidylcholine transport, and double deletion of FgDNFB and FgDNFD showed serious defects in fungal development, DON synthesis, and virulence.",Y Yun 2020,2020,5 genes,Yun-2020-Flippases play specific but distinct,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16935,PHI:10691,UniProt,I1RMF9,GenBank,CEF87437,,,PH-1,FgDnfD (FGSG_05149),chromosome 3,,,,,PHI:10692,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; coleoptile,"phospholipid-transporting ATPase, flippase",,,DON biosynthesis,reduced virulence,,,,,,reduced,reduced,reduced,,no,SDS; NaCl; calcofluor white; Congo red,SDS: CHEBI:8984; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32881238,PubMed,10.1111/mpp.12985,Mol Plant Pathol. 2020 Sep 2;21(10):1307-21. doi: 10.1111/mpp.12985. Online ahead of print,wenhuiz@fafu.edu.cn,"FgDnfB and FgDnfD had redundant functions in the regulation of phosphatidylcholine transport, and double deletion of FgDNFB and FgDNFD showed serious defects in fungal development, DON synthesis, and virulence.",Y Yun 2020,2020,5 genes,Yun-2020-Flippases play specific but distinct,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16936,PHI:10692,UniProt,I1RRL4,GenBank,CEF84829,,,PH-1,FgDnfB (FGSG_06743),chromosome 4,,,,,PHI:10691,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; coleoptile,"phospholipid-transporting ATPase, flippase",,,DON biosynthesis,reduced virulence,,,,,,reduced,reduced,reduced,,no,SDS; NaCl; calcofluor white; Congo red,SDS: CHEBI:8984; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,32881238,PubMed,10.1111/mpp.12985,Mol Plant Pathol. 2020 Sep 2;21(10):1307-21. doi: 10.1111/mpp.12985. Online ahead of print,wenhuiz@fafu.edu.cn,"FgDnfB and FgDnfD had redundant functions in the regulation of phosphatidylcholine transport, and double deletion of FgDNFB and FgDNFD showed serious defects in fungal development, DON synthesis, and virulence.",Y Yun 2020,2020,5 genes,Yun-2020-Flippases play specific but distinct,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16937,PHI:10695,UniProt,A0A0D2XH67,GenBank,KNA99247,,,4287,crpF (FOXG_03265),chromosome 8,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,root,Cu transporter protein,,,,unaffected pathogenicity,,,,,,,,,,no,CdCl2; CuSO4; ZnCl2,CdCl2: CHEBI:35456; CuSO4: CHEBI:23414; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,32862758,PubMed,10.1080/21505594.2020.1809324,Virulence. 2020 Dec;11(1):1108-1121. doi: 10.1080/21505594.2020.1809324,loidalopezfernandez@gmail.com,"Targeted deletion of crpF did not significantly alter the resistance of the fungus to macrophage killing, nor its pathogenic behaviour on the tomato plants.",D Lorenzo-Gutiérrez 2020,2020,1 gene,Lorenzo-Gutiérr-2020-Cu transporter protein Cr,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16938,PHI:10695,UniProt,A0A0D2XH67,GenBank,KNA99247,,,4287,crpF (FOXG_03265),chromosome 8,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,Cu transporter protein,,,,unaffected pathogenicity,,,,,,,,,,no,CdCl2; CuSO4; ZnCl2,CdCl2: CHEBI:35456; CuSO4: CHEBI:23414; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,32862758,PubMed,10.1080/21505594.2020.1809324,Virulence. 2020 Dec;11(1):1108-1121. doi: 10.1080/21505594.2020.1809324,loidalopezfernandez@gmail.com,"Targeted deletion of crpF did not significantly alter the resistance of the fungus to macrophage killing, nor its pathogenic behaviour on the tomato plants.",D Lorenzo-Gutiérrez 2020,2020,1 gene,Lorenzo-Gutiérr-2020-Cu transporter protein Cr,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16939,PHI:10695,UniProt,A0A0D2XH67,GenBank,KNA99247,,,4287,crpF (FOXG_03265),chromosome 8,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,rodents,10090,Mus musculus (related: house mouse),OF1,,,kidney; lung,Cu transporter protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,CdCl2; CuSO4; ZnCl2,CdCl2: CHEBI:35456; CuSO4: CHEBI:23414; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,32862758,PubMed,10.1080/21505594.2020.1809324,Virulence. 2020 Dec;11(1):1108-1121. doi: 10.1080/21505594.2020.1809324,loidalopezfernandez@gmail.com,Targeted deletion mutant ΔcrpF showed increased virulence in a murine model of systemic infection compared to wild-type strain.,D Lorenzo-Gutiérrez 2020,2020,1 gene,Lorenzo-Gutiérr-2020-Cu transporter protein Cr,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16940,PHI:10696,,no data found,GenBank,ABO10717,,,ATCC 17978,feoA (A1S_0242),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,ferrous iron transport protein A,,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16941,PHI:10697,,no data found,GenBank,ABO11221,,,ATCC 17978,mtnN (A1S_0781),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,nucleosidase,,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16942,PHI:10698,,no data found,GenBank,ABO12084,,,ATCC 17978,bnfL (A1S_1657),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,"N-acetyltransferase, baumanoferrin biosynthesis protein",,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16943,PHI:10699,,no data found,GenBank,ABO12670,,,ATCC 17978,yfgC (A1S_2247),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,putative periplasmic metalloprotease,,,,reduced virulence,,,,,,,,reduced,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16944,PHI:10700,,no data found,GenBank,ABO12809,,,ATCC 17978,basB (A1S_2390),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,acinetobactin biosynthesis protein,,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16945,PHI:10701,UniProt,A3M9P1,GenBank,ABO13635,,,ATCC 17978,hisF (A1S_3245),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,imidazole glycerol phosphate synthase cyclase subunit,,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16946,PHI:10702,,no data found,GenBank,ABO13799,,,ATCC 17978,oatA (A1S_3410),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,acyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16947,PHI:10703,,no data found,GenBank,ABO10583,,,ATCC 17978,lrp (A1S_0094),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16948,PHI:10704,,no data found,GenBank,ABO10779,,,ATCC 17978,oxygenase-like (A1S_0315),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,DNA repair system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16949,PHI:10705,,no data found,GenBank,ABO10782,,,ATCC 17978,fusE-MFP/ hylD (A1S_0318),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,membrane fusion protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16950,PHI:10706,,no data found,GenBank,ABO11328,,,ATCC 17978,pilU (A1S_0896),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,twitching motility protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16951,PHI:10707,,no data found,GenBank,ABO11460,,,ATCC 17978,ligB (A1S_1028),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,aromatic ring-opening dioxygenase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16952,PHI:10708,,no data found,GenBank,ABO13429,,,ATCC 17978,tonB-like (A1S_3032),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,biological transducer,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16953,PHI:10709,,no data found,GenBank,ABO13679,,,ATCC 17978,esvF2 (A1S_3290),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,thiaminase (transcriptional activator),,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Mutant strains lacking the feoA, mtnN, yfgC, basB, hisF, oatA and bfnL showed a significant loss of virulence in murine pneumonia.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16954,PHI:10696,,no data found,GenBank,ABO10717,,,ATCC 17978,feoA (A1S_0242),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,ferrous iron transport protein A,,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16955,PHI:10704,,no data found,GenBank,ABO10779,,,ATCC 17978,oxygenase-like (A1S_0315),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,DNA repair system,,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16956,PHI:10698,,no data found,GenBank,ABO12084,,,ATCC 17978,bnfL (A1S_1657),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"N-acetyltransferase, baumanoferrin biosynthesis protein",,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16957,PHI:10700,,no data found,GenBank,ABO12809,,,ATCC 17978,basB (A1S_2390),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,acinetobactin biosynthesis protein,,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16958,PHI:10708,,no data found,GenBank,ABO13429,,,ATCC 17978,tonB-like (A1S_3032),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,biological transducer,,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16959,PHI:10709,,no data found,GenBank,ABO13679,,,ATCC 17978,esvF2 (A1S_3290),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,thiaminase (transcriptional activator),,,,reduced virulence,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16960,PHI:10697,,no data found,GenBank,ABO11221,,,ATCC 17978,mtnN (A1S_0781),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,nucleosidase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16961,PHI:10699,,no data found,GenBank,ABO12670,,,ATCC 17978,yfgC (A1S_2247),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,putative periplasmic metalloprotease,,,,unaffected pathogenicity,,,,,,,,reduced,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16962,PHI:10701,UniProt,A3M9P1,GenBank,ABO13635,,,ATCC 17978,hisF (A1S_3245),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,imidazole glycerol phosphate synthase cyclase subunit,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16963,PHI:10702,,no data found,GenBank,ABO13799,,,ATCC 17978,oatA (A1S_3410),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,acyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16964,PHI:10703,,no data found,GenBank,ABO10583,,,ATCC 17978,lrp (A1S_0094),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16965,PHI:10705,,no data found,GenBank,ABO10782,,,ATCC 17978,fusE-MFP/ hylD (A1S_0318),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,membrane fusion protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16966,PHI:10706,,no data found,GenBank,ABO11328,,,ATCC 17978,pilU (A1S_0896),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,twitching motility protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16967,PHI:10707,,no data found,GenBank,ABO11460,,,ATCC 17978,ligB (A1S_1028),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,aromatic ring-opening dioxygenase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,ampicillin; piperacillin; tazobactam; cefoxitin; ceftazidime; cefotaxime; cefepime; imipenem; meropenem,ampicillin: CHEBI:28971; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefoxitin: CHEBI:209807; ceftazidime: CHEBI:3508; cefotaxime: CHEBI:204928; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968,,,,,gene deletion: full; gene complementation,,,YVS,32840575,PubMed,10.1093/infdis/jiaa522,J Infect Dis. 2020 Aug 25:jiaa522. doi: 10.1093/infdis/jiaa522. Online ahead of print,Margarita.Poza.Dominguez@sergas.es,"Deletion of feoA (A1S_0242), an oxygenase-like (A1S_0315), bnfL (A1S_1657), basB (A1S_2390), a tonB-like (A1S_3032) and esvF2 (A1S_3290) genes resulted in a significant reduction in the ability of ATCC 17978 to adhere to A549 human alveolar epithelial cells.",M Martínez-Guitián 2020,2020,14 genes,Martínez-Guitiá-2020-Global transcriptomic ana,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16968,PHI:10710,UniProt,Q59KN8,GenBank,AOW29092,,,SC5314,ipk1,chromosome 4,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,macrophage,inositol polyphosphate kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32833009,PubMed,10.1093/femsyr/foaa050,FEMS Yeast Res. 2020 Sep 1;20(6):foaa050. doi: 10.1093/femsyr/foaa050,nklimingchun@163.com,"The ipk1Δ/Δ mutant also displayed hypersensitivity to a series of environmental stresses, such as antifungal drugs, oxidants, cell wall perturbing agents and macrophage attacks, followed by attenuation of virulence in a mouse systematic infection model.",H Zhu 2020,2020,1 gene,Zhu-2020-The inositol polyphosphate kinase Ipk,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16969,PHI:10711,UniProt,Q63IS0,GenBank,CAH39474,,,K96243,BPSS1996,chromosome 2,,,,,,28450,Burkholderia pseudomallei,320373,MSHR668,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative exported protein,,,,reduced virulence,,,,,,,,wild type,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full; gene complementation,,,YVS,32835600,PubMed,10.1080/21505594.2020.1806675,Virulence. 2020 Dec;11(1):1041-1058. doi: 10.1080/21505594.2020.1806675,david.deshazer.civ@mail.mil,"BPSS1996 was an important B. pseudomallei virulence factor, on the other hand, BPSL2748, was not required for virulence.",S Welkos 2020,2020,2 genes,Welkos-2020-A DUF4148 family protein produced,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16970,PHI:10712,UniProt,Q63RC4,GenBank,CAH36756,,,K96243,BPSL2748,chromosome 1,,,,,,28450,Burkholderia pseudomallei,320373,MSHR668,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,alkyl hydroperoxide reductase C,,,,unaffected pathogenicity,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full; gene complementation,,,YVS,32835600,PubMed,10.1080/21505594.2020.1806675,Virulence. 2020 Dec;11(1):1041-1058. doi: 10.1080/21505594.2020.1806675,david.deshazer.civ@mail.mil,"BPSS1996 was an important B. pseudomallei virulence factor, on the other hand, BPSL2748, was not required for virulence.",S Welkos 2020,2020,2 genes,Welkos-2020-A DUF4148 family protein produced,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16971,PHI:10713,,no data found,,,,,,htpsA,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,immunogenic cell surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32815473,PubMed,10.1080/21505594.2020.1792080,Virulence. 2020 Dec;11(1):927-940. doi: 10.1080/21505594.2020.1792080,jimingao@yahoo.com,The ΔhtpsA mutant strain lost its typical encapsulated structure with decreased concentrations of sialic acid.,H Ni 2020,2020,1 gene,Ni-2020-Inactivation of the htpsA gene affects,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16972,PHI:10713,,no data found,,,,,,htpsA,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,immunogenic cell surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32815473,PubMed,10.1080/21505594.2020.1792080,Virulence. 2020 Dec;11(1):927-940. doi: 10.1080/21505594.2020.1792080,jimingao@yahoo.com,"The survival rate in whole blood, the anti-phagocytosis by RAW264.7 murine macrophage, and the adherence ability to HEp-2 cells were all significantly affected in the ?htpsA.",H Ni 2020,2020,1 gene,Ni-2020-Inactivation of the htpsA gene affects,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16973,PHI:10713,,no data found,,,,,,htpsA,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,immunogenic cell surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32815473,PubMed,10.1080/21505594.2020.1792080,Virulence. 2020 Dec;11(1):927-940. doi: 10.1080/21505594.2020.1792080,jimingao@yahoo.com,"The survival rate in whole blood, the anti-phagocytosis by RAW264.7 murine macrophage, and the adherence ability to HEp-2 cells were all significantly affected in the ?htpsA.",H Ni 2020,2020,1 gene,Ni-2020-Inactivation of the htpsA gene affects,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16974,PHI:10713,,no data found,,,,,,htpsA,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),,,,blood,immunogenic cell surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32815473,PubMed,10.1080/21505594.2020.1792080,Virulence. 2020 Dec;11(1):927-940. doi: 10.1080/21505594.2020.1792080,jimingao@yahoo.com,"The survival rate in whole blood, the anti-phagocytosis by RAW264.7 murine macrophage, and the adherence ability to HEp-2 cells were all significantly affected in the ?htpsA.",H Ni 2020,2020,1 gene,Ni-2020-Inactivation of the htpsA gene affects,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16975,PHI:10714,UniProt,D4F0Q0,GenBank,EFE24560,,,ATCC 23685,tamA,,,,,,,636,Edwardsiella tarda,,TX01,edwardsiellosis,bony fishes,244447,Cynoglossus semilaevis (related: tongue sole),,,,kidney; spleen; blood; leukocyte,autotransporter assembly factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793174,PubMed,10.3389/fmicb.2020.01743,Front Microbiol. 2020 Jul 24;11:1743. doi: 10.3389/fmicb.2020.01743. eCollection 2020,lsun@qdio.ac.cn,"TX01ΔtamA and TX01ΔtamB were signifiucantly impaired in the ability to survive under low pH and oxidizing conditions, and were unable to maintain their internal pH balance and cellular structures in acidic environments, which led to increased susceptibility to lysozyme destruction.",M F Li 2020,2020,2 genes,Li-2020-The Translocation and Assembly Module,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16976,PHI:10715,UniProt,D4F0Q2,GenBank,EFE24562,,,ATCC 23685,tamB,,,,,,,636,Edwardsiella tarda,,TX01,edwardsiellosis,bony fishes,244447,Cynoglossus semilaevis (related: tongue sole),,,,kidney; spleen; blood; leukocyte,autotransporter assembly complex proetin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32793174,PubMed,10.3389/fmicb.2020.01743,Front Microbiol. 2020 Jul 24;11:1743. doi: 10.3389/fmicb.2020.01743. eCollection 2020,lsun@qdio.ac.cn,"TX01ΔtamA and TX01ΔtamB were signifiucantly impaired in the ability to survive under low pH and oxidizing conditions, and were unable to maintain their internal pH balance and cellular structures in acidic environments, which led to increased susceptibility to lysozyme destruction.",M F Li 2020,2020,2 genes,Li-2020-The Translocation and Assembly Module,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16977,PHI:10716,UniProt,A0A384JPG6,GenBank,ATZ52244,,,B05.10,pdeR (BCIN_08g00160),BCIN08,,,,,,40559,Botrytis cinerea,,NY76,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Seokwang,,,leaf,Zn(II)2Cys6 zinc finger transcription factor,,,,reduced virulence,,,yes,,,,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32786857,PubMed,10.1021/acs.jafc.0c02420,J Agric Food Chem. 2020 Aug 26;68(34):9171-9179. doi: 10.1021/acs.jafc.0c02420. Epub 2020 Aug 15,swhan@cau.ac.kr,"When the ΔpdeR strain was inoculated onto pepper plant, the ΔpdeR strain did not cause expansion of the disease lesions from the infection sites, which grew on the surface without any penetration.",J W Han 2020,2020,1 gene,Han-2020-Transcription Factor PdeR Is Involved,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16978,PHI:10716,UniProt,A0A384JPG6,GenBank,ATZ52244,,,B05.10,pdeR (BCIN_08g00160),BCIN08,,,,,,40559,Botrytis cinerea,,NY76,grey mold,eudicots,4072,Capsicum annuum (no common name found),cv. Bugang,,,leaf,Zn(II)2Cys6 zinc finger transcription factor,,,,reduced virulence,,,yes,,,,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32786857,PubMed,10.1021/acs.jafc.0c02420,J Agric Food Chem. 2020 Aug 26;68(34):9171-9179. doi: 10.1021/acs.jafc.0c02420. Epub 2020 Aug 15,swhan@cau.ac.kr,"When the ΔpdeR strain was inoculated onto pepper plant, the ΔpdeR strain did not cause expansion of the disease lesions from the infection sites, which grew on the surface without any penetration.",J W Han 2020,2020,1 gene,Han-2020-Transcription Factor PdeR Is Involved,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16979,PHI:10717,UniProt,Q180Y6,GenBank,CAJ70391,,,630,Rho,,contains stop codons early in the rho coding sequence: N66-FS (stop codon at position 73),,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,transcription termination factor Rho,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,,,,,,,gene mutation,,,YVS,32785266,PubMed,10.1371/journal.ppat.1008708,PLoS Pathog. 2020 Aug 12;16(8):e1008708. doi: 10.1371/journal.ppat.1008708. eCollection 2020 Aug,rita_tamayo@med.unc.edu,"Rho was important for initial colonization of the intestine in a mouse model of infection, which may in part be due to the sporulation and growth defects observed in the rho mutants.",D Trzilova 2020,2020,1 gene,Trzilova-2020-Rho factor mediates flagellum an,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16980,PHI:10717,UniProt,Q180Y6,GenBank,CAJ70391,,,630,Rho,,contains stop codons early in the rho coding sequence: E113-St,,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,transcription termination factor Rho,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,,,,,,,gene mutation,,,YVS,32785266,PubMed,10.1371/journal.ppat.1008708,PLoS Pathog. 2020 Aug 12;16(8):e1008708. doi: 10.1371/journal.ppat.1008708. eCollection 2020 Aug,rita_tamayo@med.unc.edu,"Rho was important for initial colonization of the intestine in a mouse model of infection, which may in part be due to the sporulation and growth defects observed in the rho mutants.",D Trzilova 2020,2020,1 gene,Trzilova-2020-Rho factor mediates flagellum an,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16981,PHI:10718,UniProt,G3C9N7,GenBank,CCC55813,,,Emoy2,HaRxL21,,,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32785253,PubMed,10.1371/journal.ppat.1008835,PLoS Pathog. 2020 Aug 12;16(8):e1008835. doi: 10.1371/journal.ppat.1008835. eCollection 2020 Aug,Jens.Steinbrenner@agrar.uni-giessen.de,"RxL21 and TPL interact via an EAR motif at the C-terminus of the effector, mimicking the host plant mechanism for recruiting TPL to sites of transcriptional repression which was necessary for the virulence function of the effector.",S Harvey 2020,2020,1 gene,Harvey-2020-Downy Mildew effector HaRxL21 inte,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16982,PHI:10718,UniProt,G3C9N7,GenBank,CCC55813,,,Emoy2,HaRxL21,,RxL21ΔEAR,,,,,272952,Hyaloperonospora arabidopsidis,559515,Emoy2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene mutation,,,YVS,32785253,PubMed,10.1371/journal.ppat.1008835,PLoS Pathog. 2020 Aug 12;16(8):e1008835. doi: 10.1371/journal.ppat.1008835. eCollection 2020 Aug,Jens.Steinbrenner@agrar.uni-giessen.de,"RxL21 and TPL interact via an EAR motif at the C-terminus of the effector, mimicking the host plant mechanism for recruiting TPL to sites of transcriptional repression which was necessary for the virulence function of the effector.",S Harvey 2020,2020,1 gene,Harvey-2020-Downy Mildew effector HaRxL21 inte,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16983,PHI:10719,UniProt,A0A177DHG5,GenBank,OAG18808,,,SRC1lrK2f,Aatfb5,,,,Aatbf2,UniProt: A0A177DAI7; GenBank: OAG16227,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,basal transcription factor II H (TFIIH) subunit,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,methyl methanesulfonate (MMS); hydroxyurea; cisplatin; hydrogen peroxide; diethyl maleate; cumyl hydroperoxide; menadione; tert-butyl-hydroxyperoxide; sodium dodecyl sulphate; Congo red; calcofluor white,methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899; hydrogen peroxide: CHEBI:16240; diethyl maleate: CHEBI:68508; cumyl hydroperoxide: CHEBI:78673; menadione: CHEBI:28869; tert-butyl-hydroxyperoxide: CHEBI:64090; sodium dodecyl sulphate: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,32776683,PubMed,10.1111/mpp.12982,Mol Plant Pathol. 2020 Aug 10;21(10):1337-52. doi: 10.1111/mpp.12982. Online ahead of print,hyli@zju.edu.cn,"A. alternata tfb5 was required for resistance to DNA-damaging and oxidative stress, maintenance of surface hydrophobicity, and cell wall integrity and full virulence.",H Fu 2020,2020,3 genes,Fu-2020-The basal transcription factor II H su,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16984,PHI:10720,,no data found,GenBank,OWY43683,,,Z7,Aacut2 (AALT_g5432),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,basal transcription factor II H (TFIIH) subunit,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,methyl methanesulfonate (MMS); hydroxyurea; cisplatin; hydrogen peroxide; diethyl maleate; cumyl hydroperoxide; menadione; tert-butyl-hydroxyperoxide; sodium dodecyl sulphate; Congo red; calcofluor white,methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899; hydrogen peroxide: CHEBI:16240; diethyl maleate: CHEBI:68508; cumyl hydroperoxide: CHEBI:78673; menadione: CHEBI:28869; tert-butyl-hydroxyperoxide: CHEBI:64090; sodium dodecyl sulphate: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,32776683,PubMed,10.1111/mpp.12982,Mol Plant Pathol. 2020 Aug 10;21(10):1337-52. doi: 10.1111/mpp.12982. Online ahead of print,hyli@zju.edu.cn,"Necrotic lesions induced by the ΔAacut2, ΔAacut15 single and double mutation strain were significantly smaller than those induced by Z7.",H Fu 2020,2020,3 genes,Fu-2020-The basal transcription factor II H su,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16985,PHI:10721,,no data found,GenBank,OWY50335,,,Z7,Aacut15 (AALT_g7939),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,basal transcription factor II H (TFIIH) subunit,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,methyl methanesulfonate (MMS); hydroxyurea; cisplatin; hydrogen peroxide; diethyl maleate; cumyl hydroperoxide; menadione; tert-butyl-hydroxyperoxide; sodium dodecyl sulphate; Congo red; calcofluor white,methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899; hydrogen peroxide: CHEBI:16240; diethyl maleate: CHEBI:68508; cumyl hydroperoxide: CHEBI:78673; menadione: CHEBI:28869; tert-butyl-hydroxyperoxide: CHEBI:64090; sodium dodecyl sulphate: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,32776683,PubMed,10.1111/mpp.12982,Mol Plant Pathol. 2020 Aug 10;21(10):1337-52. doi: 10.1111/mpp.12982. Online ahead of print,hyli@zju.edu.cn,"Necrotic lesions induced by the ΔAacut2, ΔAacut15 single and double mutation strain were significantly smaller than those induced by Z7.",H Fu 2020,2020,3 genes,Fu-2020-The basal transcription factor II H su,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16986,PHI:10720,,no data found,GenBank,OWY43683,,,Z7,Aacut2 (AALT_g5432),,,,,,PHI:10721,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,basal transcription factor II H (TFIIH) subunit,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,methyl methanesulfonate (MMS); hydroxyurea; cisplatin; hydrogen peroxide; diethyl maleate; cumyl hydroperoxide; menadione; tert-butyl-hydroxyperoxide; sodium dodecyl sulphate; Congo red; calcofluor white,methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899; hydrogen peroxide: CHEBI:16240; diethyl maleate: CHEBI:68508; cumyl hydroperoxide: CHEBI:78673; menadione: CHEBI:28869; tert-butyl-hydroxyperoxide: CHEBI:64090; sodium dodecyl sulphate: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,32776683,PubMed,10.1111/mpp.12982,Mol Plant Pathol. 2020 Aug 10;21(10):1337-52. doi: 10.1111/mpp.12982. Online ahead of print,hyli@zju.edu.cn,"Necrotic lesions induced by the ΔAacut2, ΔAacut15 single and double mutation strain were significantly smaller than those induced by Z7.",H Fu 2020,2020,3 genes,Fu-2020-The basal transcription factor II H su,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16987,PHI:10721,,no data found,GenBank,OWY50335,,,Z7,Aacut15 (AALT_g7939),,,,,,PHI:10720,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,basal transcription factor II H (TFIIH) subunit,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,methyl methanesulfonate (MMS); hydroxyurea; cisplatin; hydrogen peroxide; diethyl maleate; cumyl hydroperoxide; menadione; tert-butyl-hydroxyperoxide; sodium dodecyl sulphate; Congo red; calcofluor white,methyl methanesulfonate (MMS): CHEBI:25255; hydroxyurea: CHEBI:44423; cisplatin: CHEBI:27899; hydrogen peroxide: CHEBI:16240; diethyl maleate: CHEBI:68508; cumyl hydroperoxide: CHEBI:78673; menadione: CHEBI:28869; tert-butyl-hydroxyperoxide: CHEBI:64090; sodium dodecyl sulphate: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,32776683,PubMed,10.1111/mpp.12982,Mol Plant Pathol. 2020 Aug 10;21(10):1337-52. doi: 10.1111/mpp.12982. Online ahead of print,hyli@zju.edu.cn,"Necrotic lesions induced by the ΔAacut2, ΔAacut15 single and double mutation strain were significantly smaller than those induced by Z7.",H Fu 2020,2020,3 genes,Fu-2020-The basal transcription factor II H su,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16988,PHI:10722,,no data found,GenBank,AWB76402,,,A1552,VqmA,,"point mutation was detected at nucleotide position 1358, causing the F453S mutation; point mutation at 1979 (C→T)",,,,,666,Vibrio cholerae,1124478,C6706,cholera,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,quorum-sensing receptor-transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32723922,PubMed,10.1128/mBio.01572-20,mBio. 2020 Jul 28;11(4):e01572-20. doi: 10.1128/mBio.01572-20,bbassler@princeton.edu,The presence of bile salts increased V. cholerae-mediated cytotoxicity to Caco-2 cells with the ΔvqmA strain driving twice as much killing as WT V. cholerae.,A A Mashruwala 2020,2020,1 gene,Mashruwala-2020-The Vibrio cholerae Quorum-Sen,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16989,PHI:10723,UniProt,D2TJZ5,GenBank,CBG87124,,,ICC168,cexE,,,,,,,67825,Citrobacter rodentium,,GPM1831a,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,small intestine; large intestine,secreted coat protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32714302,PubMed,10.3389/fmicb.2020.01374,Front Microbiol. 2020 Jun 30;11:1374. doi: 10.3389/fmicb.2020.01374. eCollection 2020,gmunson@miami.edu,A cexE mutant was significantly attenuated with 45% neonate survival.,Z P Rivas 2020,2020,2 genes,Rivas-2020-CexE Is a Coat Protein and Virulenc,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16990,PHI:10724,,no data found,,,,,,cexC,,,,,,,67825,Citrobacter rodentium,,GPM1831a,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,small intestine; large intestine,putative ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32714302,PubMed,10.3389/fmicb.2020.01374,Front Microbiol. 2020 Jun 30;11:1374. doi: 10.3389/fmicb.2020.01374. eCollection 2020,gmunson@miami.edu,"Insertion mutants of cexC, the putative ATPase of the CexE secretion system, were attenuated in our murine model.",Z P Rivas 2020,2020,2 genes,Rivas-2020-CexE Is a Coat Protein and Virulenc,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16991,PHI:10725,UniProt,C5M2V0,GenBank,XP_002545608,,,MYA-3404,ron1,,,,,,,5482,Candida tropicalis,294747,ATCC MYA-3404,oral mucosa infection; genital tract infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney; brain,NDT80 domain-containing protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32712662,PubMed,10.1093/mmy/myaa063,Med Mycol. 2020 Jul 25:myaa063. doi: 10.1093/mmy/myaa063. Online ahead of print,chinghsuanlin@ntu.edu.tw,"CtRON1, but not CaRON1, deletion mutants exhibited signifcantly impaired hyphal growth and bioflm formation.",Y D Song 2020,2020,1 gene,Song-2020-Candida tropicalis RON1 is required,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16992,PHI:10726,UniProt,Q8PBY6,GenBank,AAM40280,,,ATCC 33913,clpP,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain Xc17,black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,ATP-dependent Clp protease proteolytic subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32623486,PubMed,10.1007/s00284-020-02093-1,Curr Microbiol. 2020 Oct;77(10):2876-2885. doi: 10.1007/s00284-020-02093-1. Epub 2020 Jul 4,ymhsiao@ctust.edu.tw,"Inactivation of clpP also revealed an attenuation of virulence on the host plant and a reduction in the production of extracellular cellulase, mannanase, pectinase, and protease.",C E Li 2020,2020,1 gene,Li-2020-Functional Characterization and Transc,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16993,PHI:10727,UniProt,A0A0H3PAK7,GenBank,EAQ73232,,,81-176,pepP (CJJ81176_0681),,,,,,,197,Campylobacter jejuni,354242,81-176,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,stomach; duodenum; ileum; colon; liver; lung; kidney; mesenteric lymph node,aminopeptidase P family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32584649,PubMed,10.1080/19490976.2020.1770017,Gut Microbes. 2020 Nov 9;12(1):1770017. doi: 10.1080/19490976.2020.1770017. Epub 2020 Jun 25,stefen.backert@fau.de,Apoptosis in the colon was signifcantly diminished in mice infected with the pepP mutant highlighted the epithelial layer as the first and main target of PepP in the intestine.,M M Heimesaat 2020,2020,1 gene,Heimesaat-2020-Peptidase PepP is a novel virul,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16994,PHI:10728,UniProt,Q71YZ2,GenBank,AAT04472,,,4b F2365,menD,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16995,PHI:10729,UniProt,Q8Y6K7,GenBank,CAC99755,,,EGD-e,menA,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver,"1,4-dihydroxy-2-naphthoate octaprenyltransferase",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16996,PHI:10730,UniProt,A0A0B8R3T8,GenBank,GAM95310,,,NIHS-28,ytoI,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),L2 cell line,,,fibroblast cell line,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16997,PHI:10728,UniProt,Q71YZ2,GenBank,AAT04472,,,4b F2365,menD,,,,,,PHI:10730,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),L2 cell line,,,fibroblast cell line,2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16998,PHI:10730,UniProt,A0A0B8R3T8,GenBank,GAM95310,,,NIHS-28,ytoI,,,,,,PHI:10728,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),L2 cell line,,,fibroblast cell line,conserved hypothetical protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 16999,PHI:10728,UniProt,Q71YZ2,GenBank,AAT04472,,,4b F2365,menD,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),,,,spleen; liver,2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17000,PHI:10730,UniProt,A0A0B8R3T8,GenBank,GAM95310,,,NIHS-28,ytoI,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),,,,macrophage,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17001,PHI:10728,UniProt,Q71YZ2,GenBank,AAT04472,,,4b F2365,menD,,,,,,PHI:10730,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),,,,macrophage,2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17002,PHI:10730,UniProt,A0A0B8R3T8,GenBank,GAM95310,,,NIHS-28,ytoI,,,,,,PHI:10728,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),,,,macrophage,conserved hypothetical protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17003,PHI:10728,UniProt,Q71YZ2,GenBank,AAT04472,,,4b F2365,menD,,,,,,PHI:10731,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),,,,macrophage,2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17004,PHI:10731,UniProt,Q8Y6V6,GenBank,CAC99653,,,EGD-e,lmo1575,,,,,,PHI:10728,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),,,,macrophage,putative phosphodiesterase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31685546,PubMed,10.1128/IAI.00366-19,Infect Immun. 2019 Dec 17;88(1):e00366-19. doi: 10.1128/IAI.00366-19. Print 2019 Dec 17,sauer3@wisc.edu,Clean deletion and complementation in trans confirmed that loss of ytoI could restore plaquing and cytosolic survival of DHNA-deficient L. monocytogenes.,G Y Chen 2019,2019,4 genes,Chen-2019-Mutation of the transcriptional regu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17005,PHI:10732,UniProt,A0A0K0GN93,GenBank,ACD60330,,,PXO99A,hcp1 (PXO_02047),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,leaf,Hcp family protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32547344,PubMed,10.5423/PPJ.NT.02.2020.0026,Plant Pathol J. 2020 Jun 1;36(3):289-296. doi: 10.5423/PPJ.NT.02.2020.0026,yseo2011@pusan.ac.kr,"Hcp in T6SS-2, but not T6SS-1, was involved in bacterial virulence to rice plants.",Y Choi 2020,2020,2 genes,Choi-2020-Characterization of Type VI Secretio,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17006,PHI:10733,UniProt,A0A0K0GJ58,GenBank,ACD58207,,,PXO99A,hcp2 (PXO_00264),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,leaf,Hcp family protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32547344,PubMed,10.5423/PPJ.NT.02.2020.0026,Plant Pathol J. 2020 Jun 1;36(3):289-296. doi: 10.5423/PPJ.NT.02.2020.0026,yseo2011@pusan.ac.kr,"Hcp in T6SS-2, but not T6SS-1, was involved in bacterial virulence to rice plants.",Y Choi 2020,2020,2 genes,Choi-2020-Characterization of Type VI Secretio,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17007,PHI:10733,UniProt,A0A0K0GJ58,GenBank,ACD58207,,,PXO99A,hcp2 (PXO_00264),,,,,,PHI:10732,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,leaf,Hcp family protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32547344,PubMed,10.5423/PPJ.NT.02.2020.0026,Plant Pathol J. 2020 Jun 1;36(3):289-296. doi: 10.5423/PPJ.NT.02.2020.0026,yseo2011@pusan.ac.kr,"Hcp in T6SS-2, but not T6SS-1, was involved in bacterial virulence to rice plants.",Y Choi 2020,2020,2 genes,Choi-2020-Characterization of Type VI Secretio,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17008,PHI:10732,UniProt,A0A0K0GN93,GenBank,ACD60330,,,PXO99A,hcp1 (PXO_02047),,,,,,PHI:10733,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight,monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,leaf,Hcp family protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32547344,PubMed,10.5423/PPJ.NT.02.2020.0026,Plant Pathol J. 2020 Jun 1;36(3):289-296. doi: 10.5423/PPJ.NT.02.2020.0026,yseo2011@pusan.ac.kr,"Hcp in T6SS-2, but not T6SS-1, was involved in bacterial virulence to rice plants.",Y Choi 2020,2020,2 genes,Choi-2020-Characterization of Type VI Secretio,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17009,PHI:10734,UniProt,P29717,GenBank,CAA39908,,,ATCC 10261,XOG1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,"glucan 1,3-beta-glucosidase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,weaker defence response,gene deletion: full; gene complementation,,,YVS,32636248,PubMed,10.1128/mBio.00984-20,mBio. 2020 Jul 7;11(4):e00984-20. doi: 10.1128/mBio.00984-20,a.j.p.brown@exeter.ac.uk,Either deleting XOG1 or inhibiting exoglucanase significantly attenuated lactate-induced beta-glucan remodeling and innate immune evasion.,D S Childers 2020,2020,1 gene,Childers-2020-Epitope Shaving Promotes Fungal,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17010,PHI:10734,UniProt,P29717,GenBank,CAA39908,,,ATCC 10261,XOG1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,"glucan 1,3-beta-glucosidase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,weaker defence response,gene deletion: full; gene complementation,,,YVS,32636248,PubMed,10.1128/mBio.00984-20,mBio. 2020 Jul 7;11(4):e00984-20. doi: 10.1128/mBio.00984-20,a.j.p.brown@exeter.ac.uk,Either deleting XOG1 or inhibiting exoglucanase significantly attenuated lactate-induced beta-glucan remodeling and innate immune evasion.,D S Childers 2020,2020,1 gene,Childers-2020-Epitope Shaving Promotes Fungal,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17011,PHI:10734,UniProt,P29717,GenBank,CAA39908,,,ATCC 10261,XOG1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"glucan 1,3-beta-glucosidase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32636248,PubMed,10.1128/mBio.00984-20,mBio. 2020 Jul 7;11(4):e00984-20. doi: 10.1128/mBio.00984-20,a.j.p.brown@exeter.ac.uk,Either deleting XOG1 or inhibiting exoglucanase significantly attenuated lactate-induced beta-glucan remodeling and innate immune evasion.,D S Childers 2020,2020,1 gene,Childers-2020-Epitope Shaving Promotes Fungal,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17012,PHI:10735,UniProt,A0A384J7N9,GenBank,XP_024546792,,,B05.10,Jar1 (BCIN_02g00190),chromosome 2,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,monocots,4679,Allium cepa (related: onion),,,,leaf epidermis,H3K4 demethylase,,,,reduced virulence,,yes,yes,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31529514,PubMed,10.1111/nph.16200,New Phytol. 2020 Jan;225(2):930-947. doi: 10.1111/nph.16200. Epub 2019 Oct 16,qmqin@jlu.edu.cn,"Loss of BcJAR1 impaired conidiation, appressorium formation and stress adaptation; abolished infection cushion formation and virulence, but promoted sclerotium production in the ΔBcjar1 mutants.",J Hou 2019,2019,1 gene,Hou-2019-The H3K4 demethylase Jar1 orchestrate,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17013,PHI:10736,UniProt,A0A1H1XDV4,GenBank,OUM09249,,,PDD-32b-74,algU,,,,,,PHI:10737; PHI:10738,317,Pseudomonas syringae,223283,pv. tomato strain DC3000 D36E,infection,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31740494,PubMed,10.1128/JB.00418-19,J Bacteriol. 2020 Jan 29;202(4):e00418-19. doi: 10.1128/JB.00418-19. Print 2020 Jan 29,bryan.swingle@ars.usda.gov,AlgU was necessary for downregulating bacterial flagellin expression in planta and that this resulted in a corresponding reduction in plant immune elicitation.,Z Bao 2019,2019,4 genes,Bao-2019-Pseudomonas syringae AlgU downregulat,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17014,PHI:10737,UniProt,Q87XF5,GenBank,AAO57679,,,DC3000,mucA,,,,,,PHI:10736; PHI:10738,317,Pseudomonas syringae,223283,pv. tomato strain DC3000 D36E,infection,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,sigma factor algU negative regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31740494,PubMed,10.1128/JB.00418-19,J Bacteriol. 2020 Jan 29;202(4):e00418-19. doi: 10.1128/JB.00418-19. Print 2020 Jan 29,bryan.swingle@ars.usda.gov,AlgU was necessary for downregulating bacterial flagellin expression in planta and that this resulted in a corresponding reduction in plant immune elicitation.,Z Bao 2019,2019,4 genes,Bao-2019-Pseudomonas syringae AlgU downregulat,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17015,PHI:10738,UniProt,Q87XF6,GenBank,AAO57678,,,DC3000,mucB,,,,,,PHI:10736; PHI:10737,317,Pseudomonas syringae,223283,pv. tomato strain DC3000 D36E,infection,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,sigma factor algU regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31740494,PubMed,10.1128/JB.00418-19,J Bacteriol. 2020 Jan 29;202(4):e00418-19. doi: 10.1128/JB.00418-19. Print 2020 Jan 29,bryan.swingle@ars.usda.gov,AlgU was necessary for downregulating bacterial flagellin expression in planta and that this resulted in a corresponding reduction in plant immune elicitation.,Z Bao 2019,2019,4 genes,Bao-2019-Pseudomonas syringae AlgU downregulat,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17016,PHI:10739,UniProt,Q884Y7,GenBank,AAO55467,,,DC3000,fliC,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000 D36E,infection,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31740494,PubMed,10.1128/JB.00418-19,J Bacteriol. 2020 Jan 29;202(4):e00418-19. doi: 10.1128/JB.00418-19. Print 2020 Jan 29,bryan.swingle@ars.usda.gov,AlgU was necessary for downregulating bacterial flagellin expression in planta and that this resulted in a corresponding reduction in plant immune elicitation.,Z Bao 2019,2019,4 genes,Bao-2019-Pseudomonas syringae AlgU downregulat,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17017,PHI:10736,UniProt,A0A1H1XDV4,GenBank,OUM09249,,,PDD-32b-74,algU,,,,,,PHI:10737; PHI:10738; PHI:10739,317,Pseudomonas syringae,223283,pv. tomato strain DC3000 D36E,infection,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31740494,PubMed,10.1128/JB.00418-19,J Bacteriol. 2020 Jan 29;202(4):e00418-19. doi: 10.1128/JB.00418-19. Print 2020 Jan 29,bryan.swingle@ars.usda.gov,AlgU was necessary for downregulating bacterial flagellin expression in planta and that this resulted in a corresponding reduction in plant immune elicitation.,Z Bao 2019,2019,4 genes,Bao-2019-Pseudomonas syringae AlgU downregulat,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17018,PHI:10737,UniProt,Q87XF5,GenBank,AAO57679,,,DC3000,mucA,,,,,,PHI:10736; PHI:10738; PHI:10739,317,Pseudomonas syringae,223283,pv. tomato strain DC3000 D36E,infection,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,sigma factor algU negative regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31740494,PubMed,10.1128/JB.00418-19,J Bacteriol. 2020 Jan 29;202(4):e00418-19. doi: 10.1128/JB.00418-19. Print 2020 Jan 29,bryan.swingle@ars.usda.gov,AlgU was necessary for downregulating bacterial flagellin expression in planta and that this resulted in a corresponding reduction in plant immune elicitation.,Z Bao 2019,2019,4 genes,Bao-2019-Pseudomonas syringae AlgU downregulat,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17019,PHI:10738,UniProt,Q87XF6,GenBank,AAO57678,,,DC3000,mucB,,,,,,PHI:10736; PHI:10737; PHI:10739,317,Pseudomonas syringae,223283,pv. tomato strain DC3000 D36E,infection,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,sigma factor algU regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31740494,PubMed,10.1128/JB.00418-19,J Bacteriol. 2020 Jan 29;202(4):e00418-19. doi: 10.1128/JB.00418-19. Print 2020 Jan 29,bryan.swingle@ars.usda.gov,AlgU was necessary for downregulating bacterial flagellin expression in planta and that this resulted in a corresponding reduction in plant immune elicitation.,Z Bao 2019,2019,4 genes,Bao-2019-Pseudomonas syringae AlgU downregulat,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17020,PHI:10739,UniProt,Q884Y7,GenBank,AAO55467,,,DC3000,fliC,,,,,,PHI:10736; PHI:10737; PHI:10738,317,Pseudomonas syringae,223283,pv. tomato strain DC3000 D36E,infection,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31740494,PubMed,10.1128/JB.00418-19,J Bacteriol. 2020 Jan 29;202(4):e00418-19. doi: 10.1128/JB.00418-19. Print 2020 Jan 29,bryan.swingle@ars.usda.gov,AlgU was necessary for downregulating bacterial flagellin expression in planta and that this resulted in a corresponding reduction in plant immune elicitation.,Z Bao 2019,2019,4 genes,Bao-2019-Pseudomonas syringae AlgU downregulat,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17021,PHI:10740,UniProt,F9WY41,GenBank,EGP92255,,,IPO323,107320,chromosome 1,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Obelisk,,,leaf,putative transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; sorbitol; calcofluor white; Congo red; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31702117,PubMed,10.1111/mpp.12886,Mol Plant Pathol. 2020 Jan;21(1):124-138. doi: 10.1111/mpp.12886. Epub 2019 Nov 8,estukenbrock@bot.uni-kiel.de,Zt107320 regulated the dimorphic switch as well as the growth rate of Z. tritici and affects fungal cell wall composition in vitro.,M Habig 2019,2019,1 gene,Habig-2019-The transcription factor Zt107320 a,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17022,PHI:10740,UniProt,F9WY41,GenBank,EGP92255,,,IPO323,107320,chromosome 1,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,15368,Brachypodium distachyon (related: stiff brome),cv. Bd21,,,leaf,putative transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; sorbitol; calcofluor white; Congo red; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31702117,PubMed,10.1111/mpp.12886,Mol Plant Pathol. 2020 Jan;21(1):124-138. doi: 10.1111/mpp.12886. Epub 2019 Nov 8,estukenbrock@bot.uni-kiel.de,Zt107320 regulated the dimorphic switch as well as the growth rate of Z. tritici and affects fungal cell wall composition in vitro.,M Habig 2019,2019,1 gene,Habig-2019-The transcription factor Zt107320 a,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17023,PHI:10741,UniProt,P01552,GenBank,AAA88550,,,S6,SEB,,,,,,,1280,Staphylococcus aureus,,CA-MRSA ST59 isolate RJ-2,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,enterotoxin type B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32937658,PubMed,10.1093/infdis/jiaa584,J Infect Dis. 2020 Sep 16:jiaa584. doi: 10.1093/infdis/jiaa584. Online ahead of print,motto@niaid.nih.gov,A significant contribution of seb to systemic ST59 infection that was associated with a cytokine storm was detected.,J S Bae 2020,2020,1 gene,Bae-2020-Staphylococcal enterotoxin B contribu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17024,PHI:10741,UniProt,P01552,GenBank,AAA88550,,,S6,SEB,,,,,,,1280,Staphylococcus aureus,,CA-MRSA ST59 isolate RJ-2,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCrl,,,blood; skin; lung; spleen,enterotoxin type B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32937658,PubMed,10.1093/infdis/jiaa584,J Infect Dis. 2020 Sep 16:jiaa584. doi: 10.1093/infdis/jiaa584. Online ahead of print,motto@niaid.nih.gov,A significant contribution of seb to systemic ST59 infection that was associated with a cytokine storm was detected.,J S Bae 2020,2020,1 gene,Bae-2020-Staphylococcal enterotoxin B contribu,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17025,PHI:10742,UniProt,A0A2Z5VGD9,GenBank,BBB35770,,,M2799,hvtA,,,,,,,672,Vibrio vulnificus,216895,CMCP6,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,temperature-dependent hemin uptake receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31290613,PubMed,10.1002/mbo3.905,Microbiologyopen. 2019 Oct;8(10):e905. doi: 10.1002/mbo3.905. Epub 2019 Jul 10,kenton@up.edu,The virulence genes hupA and hvtA were tightly regulated and strictly induced during iron limitation combined with the physiological temperature of the host organism.,S Datta 2019,2019,2 genes,Datta-2019-Characterization of temperature-dep,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17026,PHI:10743,UniProt,Q8GRB8,GenBank,BAC15762,,,L-180,hupA,,,,,,,672,Vibrio vulnificus,216895,CMCP6,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,temperature-dependent hemin uptake receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31290613,PubMed,10.1002/mbo3.905,Microbiologyopen. 2019 Oct;8(10):e905. doi: 10.1002/mbo3.905. Epub 2019 Jul 10,kenton@up.edu,The virulence genes hupA and hvtA were tightly regulated and strictly induced during iron limitation combined with the physiological temperature of the host organism.,S Datta 2019,2019,2 genes,Datta-2019-Characterization of temperature-dep,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17027,PHI:10742,UniProt,A0A2Z5VGD9,GenBank,BBB35770,,,M2799,hvtA,,,,,,PHI:10743,672,Vibrio vulnificus,216895,CMCP6,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,temperature-dependent hemin uptake receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31290613,PubMed,10.1002/mbo3.905,Microbiologyopen. 2019 Oct;8(10):e905. doi: 10.1002/mbo3.905. Epub 2019 Jul 10,kenton@up.edu,The virulence genes hupA and hvtA were tightly regulated and strictly induced during iron limitation combined with the physiological temperature of the host organism.,S Datta 2019,2019,2 genes,Datta-2019-Characterization of temperature-dep,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17028,PHI:10743,UniProt,Q8GRB8,GenBank,BAC15762,,,L-180,hupA,,,,,,PHI:10742,672,Vibrio vulnificus,216895,CMCP6,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,temperature-dependent hemin uptake receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31290613,PubMed,10.1002/mbo3.905,Microbiologyopen. 2019 Oct;8(10):e905. doi: 10.1002/mbo3.905. Epub 2019 Jul 10,kenton@up.edu,The virulence genes hupA and hvtA were tightly regulated and strictly induced during iron limitation combined with the physiological temperature of the host organism.,S Datta 2019,2019,2 genes,Datta-2019-Characterization of temperature-dep,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17029,PHI:10744,UniProt,A0A6N3S5J5,GenBank,ETH92467,,,STO1-CHOC-0019,BteA,,deletion of alanine residue at position 503 (BteAΔA503),,,,,520,Bordetella pertussis,743277,B1917,acute pulmonary pertussis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32776984,PubMed,10.1371/journal.ppat.1008512,PLoS Pathog. 2020 Aug 10;16(8):e1008512. doi: 10.1371/journal.ppat.1008512. eCollection 2020 Aug,kamanova@biomed.cas.cz,The deletion of A503 from Bp BteA greatly enhanced the cytotoxic activity.,J Bayram 2020,2020,2 genes,Bayram-2020-Cytotoxicity of the effector prote,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17030,PHI:10744,UniProt,A0A6N3S5J5,GenBank,ETH92467,,,STO1-CHOC-0019,BteA,,deletion of alanine residue at position 503 (BteAΔA503),,,,,520,Bordetella pertussis,743277,B1917,acute pulmonary pertussis,rodents,10090,Mus musculus (related: house mouse),BALB/cByJ,,,lung,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32776984,PubMed,10.1371/journal.ppat.1008512,PLoS Pathog. 2020 Aug 10;16(8):e1008512. doi: 10.1371/journal.ppat.1008512. eCollection 2020 Aug,kamanova@biomed.cas.cz,B. pertussis producing the more active BteAΔA503 effector triggered lower inflammatory damage of infected lungs.,J Bayram 2020,2020,2 genes,Bayram-2020-Cytotoxicity of the effector prote,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17031,PHI:10745,UniProt,L0PR31,GenBank,CCK33761,,,FR3054,BteA,,insertion of alanine residue at position 503,,,,,518,Bordetella bronchiseptica,,D445,infectious bronchitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32776984,PubMed,10.1371/journal.ppat.1008512,PLoS Pathog. 2020 Aug 10;16(8):e1008512. doi: 10.1371/journal.ppat.1008512. eCollection 2020 Aug,kamanova@biomed.cas.cz,Alanine residue inserted at position 503 (A503) of Bp BteA accounts for its strongly attenuated cytotoxic potency.,J Bayram 2020,2020,2 genes,Bayram-2020-Cytotoxicity of the effector prote,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17032,PHI:10746,UniProt,P80672,GenBank,CAL35374,,,NCTC 11168,porA,,11168porA3902-TporA and 11168porA3902,,,,,197,Campylobacter jejuni,567106,IA3902,infection,even-toed ungulates,9823,Sus scrofa (related: pig),,,,uterus; placenta,major outer membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,31570559,PubMed,10.1128/IAI.00687-19,Infect Immun. 2019 Nov 18;87(12):e00687-19. doi: 10.1128/IAI.00687-19. Print 2019 Dec,zhang123@iastate.edu,"In the guinea pig model, the C. jejuni construct with an interrupted TporA was significantly attenuated in abortion induction.",L Dai 2019,2019,1 gene,Dai-2019-The Rho-independent transcription ter,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17033,PHI:10748,UniProt,E3QFA4,GenBank,EFQ29542,,,M1.001,CLU5a (GLRG_04686),,,,,,,31870,Colletotrichum graminicola,645133,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf; stem,secreted virulence factor,,,,reduced virulence,,,yes,,,,,,,no,uvitex 2B; Congo red; NaCl; KCl,Uvitex 2B CAS no.: CAS:7128-64-5; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,31599055,PubMed,10.1111/1462-2920.14819,Environ Microbiol. 2019 Dec;21(12):4773-4791. doi: 10.1111/1462-2920.14819. Epub 2019 Oct 21,stefan.wirsel@landw.unihalle.de,"Targeted deletion of all genes of CLU5 revealed that CLU5a and CLU5d were required for full appressorial penetration competence, with virulence deficiencies.",I Eisermann 2019,2019,5 genes,Eisermann-2019-Two genes in a pathogenicity ge,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17034,PHI:10749,UniProt,E3QFA7,GenBank,EFQ29545,,,M1.001,CLU5d (GLRG_04689),,,,,,,31870,Colletotrichum graminicola,645133,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf; stem,pathogenicity cluster 5 protein d,,,,reduced virulence,,,yes,,,,,,,no,uvitex 2B; Congo red; NaCl; KCl,Uvitex 2B CAS no.: CAS:7128-64-5; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,31599055,PubMed,10.1111/1462-2920.14819,Environ Microbiol. 2019 Dec;21(12):4773-4791. doi: 10.1111/1462-2920.14819. Epub 2019 Oct 21,stefan.wirsel@landw.unihalle.de,"Targeted deletion of all genes of CLU5 revealed that CLU5a and CLU5d were required for full appressorial penetration competence, with virulence deficiencies.",I Eisermann 2019,2019,5 genes,Eisermann-2019-Two genes in a pathogenicity ge,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17035,PHI:10750,UniProt,E3QFA5,GenBank,EFQ29543,,,M1.001,CLU5b (GLRG_04687),,,,,,,31870,Colletotrichum graminicola,645133,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf; stem,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,uvitex 2B; Congo red; NaCl; KCl,Uvitex 2B CAS no.: CAS:7128-64-5; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,31599055,PubMed,10.1111/1462-2920.14819,Environ Microbiol. 2019 Dec;21(12):4773-4791. doi: 10.1111/1462-2920.14819. Epub 2019 Oct 21,stefan.wirsel@landw.unihalle.de,"Targeted deletion of all genes of CLU5 revealed that CLU5a and CLU5d were required for full appressorial penetration competence, with virulence deficiencies.",I Eisermann 2019,2019,5 genes,Eisermann-2019-Two genes in a pathogenicity ge,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17036,PHI:10751,UniProt,E3QFA6,GenBank,EFQ29544,,,M1.001,CLU5c (GLRG_04688),,,,,,,31870,Colletotrichum graminicola,645133,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf; stem,S1/P1 nuclease,,,,unaffected pathogenicity,,,,,,,,,,no,uvitex 2B; Congo red; NaCl; KCl,Uvitex 2B CAS no.: CAS:7128-64-5; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,31599055,PubMed,10.1111/1462-2920.14819,Environ Microbiol. 2019 Dec;21(12):4773-4791. doi: 10.1111/1462-2920.14819. Epub 2019 Oct 21,stefan.wirsel@landw.unihalle.de,"Targeted deletion of all genes of CLU5 revealed that CLU5a and CLU5d were required for full appressorial penetration competence, with virulence deficiencies.",I Eisermann 2019,2019,5 genes,Eisermann-2019-Two genes in a pathogenicity ge,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17037,PHI:10752,UniProt,E3QFA8,GenBank,EFQ29546,,,M1.001,CLU5e (GLRG_04690),,,,,,,31870,Colletotrichum graminicola,645133,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf; stem,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,uvitex 2B; Congo red; NaCl; KCl,Uvitex 2B CAS no.: CAS:7128-64-5; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,YVS,31599055,PubMed,10.1111/1462-2920.14819,Environ Microbiol. 2019 Dec;21(12):4773-4791. doi: 10.1111/1462-2920.14819. Epub 2019 Oct 21,stefan.wirsel@landw.unihalle.de,"Targeted deletion of all genes of CLU5 revealed that CLU5a and CLU5d were required for full appressorial penetration competence, with virulence deficiencies.",I Eisermann 2019,2019,5 genes,Eisermann-2019-Two genes in a pathogenicity ge,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17038,PHI:10753,UniProt,no data found,GenBank,,,,,LysM4,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17039,PHI:10754,UniProt,A0A0A2IBU9,GenBank,KGO55071,,,MD-8,LysM5 (PEX2_086500),,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17040,PHI:10755,UniProt,no data found,GenBank,,,,,LysM6,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants (ΔPeLysM5, ΔPeLysM7, ΔPeLysM8, ΔPeLysM9, ΔPeLysM10, ΔPeLysM11, ΔPeLysM14, ΔPeLysM15, ΔPeLysM16, ΔPeLysM18 and ΔPeLysM19) showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17041,PHI:10756,UniProt,no data found,GenBank,,,,,LysM7,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17042,PHI:10757,UniProt,no data found,GenBank,,,,,LysM8,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17043,PHI:10758,UniProt,no data found,GenBank,,,,,LysM9,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17044,PHI:10759,UniProt,no data found,GenBank,,,,,LysM10,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17045,PHI:10760,UniProt,no data found,GenBank,,,,,LysM11,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17046,PHI:10761,UniProt,no data found,GenBank,,,,,LysM12,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17047,PHI:10762,UniProt,no data found,GenBank,,,,,LysM13,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17048,PHI:10763,UniProt,no data found,GenBank,,,,,LysM14,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17049,PHI:10764,UniProt,no data found,GenBank,,,,,LysM15,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17050,PHI:10765,UniProt,no data found,GenBank,,,,,LysM16,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17051,PHI:10766,UniProt,no data found,GenBank,,,,,LysM17,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17052,PHI:10767,UniProt,no data found,GenBank,,,,,LysM18,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17053,PHI:10768,UniProt,no data found,GenBank,,,,,LysM19,,,,,,,27334,Penicillium expansum,,MD-8,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,LysM family protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32656702,PubMed,10.1007/s00438-020-01710-9,Mol Genet Genomics. 2020 Nov;295(6):1415-1429. doi: 10.1007/s00438-020-01710-9. Epub 2020 Jul 12,liuyongsheng1122@ahau.edu.cn,"The knockout mutants showed enhanced fungal virulence, with faster decaying on infected fruits than those from wild type.",D Chen 2020,2020,16 genes,Chen-2020-Multiple transcriptomic analyses and,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17054,PHI:10769,UniProt,A0A112VBE9,GenBank,CWW61749,,,2842STDY5753961,SpxA1,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,global regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32255216,PubMed,10.1111/mmi.14508,Mol Microbiol. 2020 Apr 7;114(2):230-43. doi: 10.1111/mmi.14508. Online ahead of print,reniere@uw.edu,SpxA1 was required for basal expression of scavenging enzymes to combat redox stress generated in the presence of oxygen.,M R Cesinger 2020,2020,1 gene,Cesinger-2020-Listeria monocytogenes SpxA1 is,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17055,PHI:10769,UniProt,A0A112VBE9,GenBank,CWW61749,,,2842STDY5753961,SpxA1,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,global regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32255216,PubMed,10.1111/mmi.14508,Mol Microbiol. 2020 Apr 7;114(2):230-43. doi: 10.1111/mmi.14508. Online ahead of print,reniere@uw.edu,SpxA1 was required for basal expression of scavenging enzymes to combat redox stress generated in the presence of oxygen.,M R Cesinger 2020,2020,1 gene,Cesinger-2020-Listeria monocytogenes SpxA1 is,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17056,PHI:10770,UniProt,G4MSW6,GenBank,EHA53820,,,70-15,MoSAS3 (MGG_04615),chromosome 2,,,,,,318829,Magnaporthe oryzae,,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,MYST family histone acetyltransferase,,,,loss of pathogenicity,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31364260,PubMed,10.1111/mpp.12856,Mol Plant Pathol. 2019 Nov;20(11):1491-1505. doi: 10.1111/mpp.12856. Epub 2019 Jul 30,jjeon@yu.ac.kr,"MoSAS3 deletion alone had a profound effect on fungal growth and development, including asexual reproduction, germination and ppressorium formation in M. oryzae.",A Dubey 2019,2019,2 genes,Dubey-2019-A MYST family histone acetyltransfe,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17057,PHI:10771,UniProt,G4N6S1,GenBank,EHA49888,,,70-15,MoGCN5 (MGG_03677),chromosome 4,,,,,,318829,Magnaporthe oryzae,,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,histone acetyltransferase,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31364260,PubMed,10.1111/mpp.12856,Mol Plant Pathol. 2019 Nov;20(11):1491-1505. doi: 10.1111/mpp.12856. Epub 2019 Jul 30,jjeon@yu.ac.kr,"Deletion of MoGCN5 rendering the fungus defective in growth, sporulation and pathogenicity.",A Dubey 2019,2019,2 genes,Dubey-2019-A MYST family histone acetyltransfe,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17058,PHI:10772,UniProt,B2C6F1,GenBank,ACB05902,,,R265,lac1,,,,,,,552467,Cryptococcus bacillisporus,294750,R265,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,laccase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,31871099,PubMed,10.1128/IAI.00712-19,Infect Immun. 2020 Feb 20;88(3):e00712-19. doi: 10.1128/IAI.00712-19. Print 2020 Feb 20,upornpim@tu.ac.th,Mice infected with a lac1Δmutant strain of C. gattii had reduced lung burdens at the early but not the late stage of infection. pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,A Hansakon 2019,2019,1 gene,Hansakon-2019-Contribution of laccase expressi,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17059,PHI:10772,UniProt,B2C6F1,GenBank,ACB05902,,,R265,lac1,,,,,,,552467,Cryptococcus bacillisporus,294750,R265,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,laccase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,31871099,PubMed,10.1128/IAI.00712-19,Infect Immun. 2020 Feb 20;88(3):e00712-19. doi: 10.1128/IAI.00712-19. Print 2020 Feb 20,upornpim@tu.ac.th,Laccase expression in C.gattii was responsible for the protection against macrophage function in promoting intracellular fungal growth and proliferation. pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,A Hansakon 2019,2019,1 gene,Hansakon-2019-Contribution of laccase expressi,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17060,PHI:10773,UniProt,Q2FWE8,GenBank,ABD31377,,,NCTC 8325,atpA,,,,,,,1280,Staphylococcus aureus,,USA300 LAC 13C,prosthetic joint infection,primates,9606,Homo sapiens (related: human),,,,macrophage,ATP synthase subunit alpha,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32900803,PubMed,10.1128/mBio.01581-20,mBio. 2020 Sep 8;11(5):e01581-20. doi: 10.1128/mBio.01581-20,tkielian@unmc.edu,Coculture of MDSCs and macrophages with ΔatpA biofilm elicited significant increases in the proinflammatory cytokines.,M E Bosch 2020,2020,1 gene,Bosch-2020-Staphylococcus aureus ATP Synthase,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17061,PHI:10773,UniProt,Q2FWE8,GenBank,ABD31377,,,NCTC 8325,atpA,,,,,,,1280,Staphylococcus aureus,,USA300 LAC 13C,prosthetic joint infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCrl,,,bone marrow myeloid-derived suppressor cell (MDSC); macrophage; knee joint; femur,ATP synthase subunit alpha,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32900803,PubMed,10.1128/mBio.01581-20,mBio. 2020 Sep 8;11(5):e01581-20. doi: 10.1128/mBio.01581-20,tkielian@unmc.edu,"In a mouse model of prosthetic joint infection (PJI), ΔatpA-infected mice had decreased MDSCs concomitant with increased monocyte/ macrophage infiltrates and proinflammatory cytokine production, which resulted in biofilm clearance.",M E Bosch 2020,2020,1 gene,Bosch-2020-Staphylococcus aureus ATP Synthase,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17062,PHI:10774,UniProt,A0A0K0GG54,GenBank,ACD57163,,,PXO99A,XopX,,xopX S193A; xopX S477A; XopX S84A; XopX T430A; XopX T621A,,xopQ,UniProt: G7TIR4; GenBank: AEQ94357,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene mutation: characterised,,,YVS,32654337,PubMed,10.1111/tpj.14924,Plant J. 2020 Jul 12. doi: 10.1111/tpj.14924. Online ahead of print,sonti@nipgr.ac.in,Mutation of either serine-193 or serine-477 containing 14-3-3 protein-binding motifs of XopX abolished the ability ofthe protein to suppress rice immune responses.,S Deb 2020,2020,1 gene,Deb-2020-Interaction of the Xanthomonas effect,BATCH_102B,2020-10-01,MC,,,,,,,,,,,,,
,,Record 17063,PHI:10775,UniProt,Q9I4X9,GenBank,AE004532_3,,,PAO1,PA0990,,,,,,,287,Pseudomonas aeruginosa,,PAO1161,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,nudix hydrolase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32419387,PubMed,10.1002/mbo3.1052,Microbiologyopen. 2020 Aug;9(8):e1052. doi: 10.1002/mbo3.1052. Epub 2020 May 17,elzbietak@ibb.waw.pl,"The ΔPA3470, ΔPA3754, and ΔPA4400 mutants showed increased pyocyanin production, were more resistant to the beta-lactam antibiotic piperacillin, and were more sensitive to killing by H2O2.",J Drabinska 2020,2020,9 genes,Drabinska-2020-Individual Nudix hydrolases aff,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17064,PHI:10776,UniProt,Q9I074,GenBank,AE004704_11,,,PAO1,PA2769,,,,,,,287,Pseudomonas aeruginosa,,PAO1161,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,nudix hydrolase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32419387,PubMed,10.1002/mbo3.1052,Microbiologyopen. 2020 Aug;9(8):e1052. doi: 10.1002/mbo3.1052. Epub 2020 May 17,elzbietak@ibb.waw.pl,"The ΔPA3470, ΔPA3754, and ΔPA4400 mutants showed increased pyocyanin production, were more resistant to the beta-lactam antibiotic piperacillin, and were more sensitive to killing by H2O2.",J Drabinska 2020,2020,9 genes,Drabinska-2020-Individual Nudix hydrolases aff,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17065,PHI:10777,UniProt,Q9HZ54,GenBank,AE004742_4,,,PAO1,PA3180,,,,,,,287,Pseudomonas aeruginosa,,PAO1161,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,nudix hydrolase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32419387,PubMed,10.1002/mbo3.1052,Microbiologyopen. 2020 Aug;9(8):e1052. doi: 10.1002/mbo3.1052. Epub 2020 May 17,elzbietak@ibb.waw.pl,"The ΔPA3470, ΔPA3754, and ΔPA4400 mutants showed increased pyocyanin production, were more resistant to the beta-lactam antibiotic piperacillin, and were more sensitive to killing by H2O2.",J Drabinska 2020,2020,9 genes,Drabinska-2020-Individual Nudix hydrolases aff,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17066,PHI:10778,UniProt,Q9HYD6,GenBank,AE004768_3,,,PAO1,PA3470,,,,,,,287,Pseudomonas aeruginosa,,PAO1161,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,nudix hydrolase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32419387,PubMed,10.1002/mbo3.1052,Microbiologyopen. 2020 Aug;9(8):e1052. doi: 10.1002/mbo3.1052. Epub 2020 May 17,elzbietak@ibb.waw.pl,"The ΔPA3470, ΔPA3754, and ΔPA4400 mutants showed increased pyocyanin production, were more resistant to the beta-lactam antibiotic piperacillin, and were more sensitive to killing by H2O2.",J Drabinska 2020,2020,9 genes,Drabinska-2020-Individual Nudix hydrolases aff,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17067,PHI:10779,UniProt,Q9HXP1,GenBank,AE004794_6,,,PAO1,PA3754,,,,,,,287,Pseudomonas aeruginosa,,PAO1161,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,nudix hydrolase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32419387,PubMed,10.1002/mbo3.1052,Microbiologyopen. 2020 Aug;9(8):e1052. doi: 10.1002/mbo3.1052. Epub 2020 May 17,elzbietak@ibb.waw.pl,"The ΔPA3470, ΔPA3754, and ΔPA4400 mutants showed increased pyocyanin production, were more resistant to the beta-lactam antibiotic piperacillin, and were more sensitive to killing by H2O2.",J Drabinska 2020,2020,9 genes,Drabinska-2020-Individual Nudix hydrolases aff,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17068,PHI:10780,UniProt,Q9HXP0,GenBank,AE004794_7,,,PAO1,PA3755,,,,,,,287,Pseudomonas aeruginosa,,PAO1161,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,nudix hydrolase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32419387,PubMed,10.1002/mbo3.1052,Microbiologyopen. 2020 Aug;9(8):e1052. doi: 10.1002/mbo3.1052. Epub 2020 May 17,elzbietak@ibb.waw.pl,"The ΔPA3470, ΔPA3754, and ΔPA4400 mutants showed increased pyocyanin production, were more resistant to the beta-lactam antibiotic piperacillin, and were more sensitive to killing by H2O2.",J Drabinska 2020,2020,9 genes,Drabinska-2020-Individual Nudix hydrolases aff,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17069,PHI:10781,UniProt,Q9HW06,GenBank,AE004855_10,,,PAO1,PA4400,,,,,,,287,Pseudomonas aeruginosa,,PAO1161,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,probable pyrophosphohydrolase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32419387,PubMed,10.1002/mbo3.1052,Microbiologyopen. 2020 Aug;9(8):e1052. doi: 10.1002/mbo3.1052. Epub 2020 May 17,elzbietak@ibb.waw.pl,"The ΔPA3470, ΔPA3754, and ΔPA4400 mutants showed increased pyocyanin production, were more resistant to the beta-lactam antibiotic piperacillin, and were more sensitive to killing by H2O2.",J Drabinska 2020,2020,9 genes,Drabinska-2020-Individual Nudix hydrolases aff,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17070,PHI:10782,UniProt,Q9HUW9,GenBank,AE004897_4,,,PAO1,PA4841,,,,,,,287,Pseudomonas aeruginosa,,PAO1161,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,nudix hydrolase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32419387,PubMed,10.1002/mbo3.1052,Microbiologyopen. 2020 Aug;9(8):e1052. doi: 10.1002/mbo3.1052. Epub 2020 May 17,elzbietak@ibb.waw.pl,"The ΔPA3470, ΔPA3754, and ΔPA4400 mutants showed increased pyocyanin production, were more resistant to the beta-lactam antibiotic piperacillin, and were more sensitive to killing by H2O2.",J Drabinska 2020,2020,9 genes,Drabinska-2020-Individual Nudix hydrolases aff,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17071,PHI:10783,UniProt,Q9HU13,GenBank,AE004930_7,,,PAO1,PA5176,,,,,,,287,Pseudomonas aeruginosa,,PAO1161,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,larva,nudix hydrolase domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32419387,PubMed,10.1002/mbo3.1052,Microbiologyopen. 2020 Aug;9(8):e1052. doi: 10.1002/mbo3.1052. Epub 2020 May 17,elzbietak@ibb.waw.pl,"The ΔPA3470, ΔPA3754, and ΔPA4400 mutants showed increased pyocyanin production, were more resistant to the beta-lactam antibiotic piperacillin, and were more sensitive to killing by H2O2.",J Drabinska 2020,2020,9 genes,Drabinska-2020-Individual Nudix hydrolases aff,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17072,PHI:10784,UniProt,D0P1B2,GenBank,EEY54138,,,T30-4,PITG20303,,,,,,,4787,Phytophthora infestans,,14-3-GFP,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,RxLR effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,32772378,PubMed,10.1111/nph.16861,New Phytol. 2020 Aug 9. doi: 10.1111/nph.16861. Online ahead of print,wxshan@nwafu.edu.cn,"Phytophthora infestans RXLR effector PITG20303, suppressed PAMP-triggered immunity (PTI) and promoted pathogen colonization by targeting and stabilizing a potato MAPK cascade protein, StMKK1.",Y Du 2020,2020,1 gene,Du-2020-Phytophthora infestans RXLR effector P,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17073,PHI:10785,UniProt,no data found,GenBank,CBI50258,,,TW20,MspA (SATW20_23930),,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,subcutaneous infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; blood; kidney; spleen; liver,small membrane-bound protein,,,,reduced virulence,,,,,,,,,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,YVS,32571989,PubMed,10.1128/IAI.00162-20,Infect Immun. 2020 Aug 19;88(9):e00162-20. doi: 10.1128/IAI.00162-20. Print 2020 Aug 19,ruth.massey@bristol.ac.uk,Inactivation of mspA protein resulted in the loss of the ability of S. aureus to secrete cytolytic toxins.,S Duggan 2020,2020,2 genes,Duggan-2020-A Small Membrane Stabilizing Prote,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17074,PHI:10786,UniProt,Q2FWM7,GenBank,AF230358_2,,,RN4220,agrB,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,subcutaneous infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,skin; blood; kidney; spleen; liver,accessory gene regulatory protein,,,,reduced virulence,,,,,,,,,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,YVS,32571989,PubMed,10.1128/IAI.00162-20,Infect Immun. 2020 Aug 19;88(9):e00162-20. doi: 10.1128/IAI.00162-20. Print 2020 Aug 19,ruth.massey@bristol.ac.uk,Inactivation of mspA protein resulted in the loss of the ability of S. aureus to secrete cytolytic toxins.,S Duggan 2020,2020,2 genes,Duggan-2020-A Small Membrane Stabilizing Prote,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17075,PHI:10785,UniProt,no data found,GenBank,CBI50258,,,TW20,MspA,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,subcutaneous infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,small membrane-bound protein,,,,reduced virulence,,,,,,,,,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,YVS,32571989,PubMed,10.1128/IAI.00162-20,Infect Immun. 2020 Aug 19;88(9):e00162-20. doi: 10.1128/IAI.00162-20. Print 2020 Aug 19,ruth.massey@bristol.ac.uk,Inactivation of mspA protein resulted in the loss of the ability of S. aureus to secrete cytolytic toxins.,S Duggan 2020,2020,2 genes,Duggan-2020-A Small Membrane Stabilizing Prote,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17076,PHI:10785,UniProt,no data found,GenBank,CBI50258,,,TW20,MspA,,,,,,,1280,Staphylococcus aureus,,SH1000,subcutaneous infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,small membrane-bound protein,,,,reduced virulence,,,,,,,,,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,YVS,32571989,PubMed,10.1128/IAI.00162-20,Infect Immun. 2020 Aug 19;88(9):e00162-20. doi: 10.1128/IAI.00162-20. Print 2020 Aug 19,ruth.massey@bristol.ac.uk,Inactivation of mspA protein resulted in the loss of the ability of S. aureus to secrete cytolytic toxins.,S Duggan 2020,2020,2 genes,Duggan-2020-A Small Membrane Stabilizing Prote,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17077,PHI:10785,UniProt,no data found,GenBank,CBI50258,,,TW20,MspA,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,subcutaneous infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,small membrane-bound protein,,,,reduced virulence,,,,,,,,,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,YVS,32571989,PubMed,10.1128/IAI.00162-20,Infect Immun. 2020 Aug 19;88(9):e00162-20. doi: 10.1128/IAI.00162-20. Print 2020 Aug 19,ruth.massey@bristol.ac.uk,Inactivation of mspA protein resulted in the loss of the ability of S. aureus to secrete cytolytic toxins.,S Duggan 2020,2020,2 genes,Duggan-2020-A Small Membrane Stabilizing Prote,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17078,PHI:10785,UniProt,no data found,GenBank,CBI50258,,,TW20,MspA,,,,,,,1280,Staphylococcus aureus,,SH1000,subcutaneous infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,small membrane-bound protein,,,,reduced virulence,,,,,,,,,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,YVS,32571989,PubMed,10.1128/IAI.00162-20,Infect Immun. 2020 Aug 19;88(9):e00162-20. doi: 10.1128/IAI.00162-20. Print 2020 Aug 19,ruth.massey@bristol.ac.uk,Inactivation of mspA protein resulted in the loss of the ability of S. aureus to secrete cytolytic toxins.,S Duggan 2020,2020,2 genes,Duggan-2020-A Small Membrane Stabilizing Prote,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17079,PHI:10785,UniProt,no data found,GenBank,CBI50258,,,TW20,MspA,,,,,,,1280,Staphylococcus aureus,367830,USA300 JE2,subcutaneous infection,primates,9606,Homo sapiens (related: human),,,,blood,small membrane-bound protein,,,,reduced virulence,,,,,,,,,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,YVS,32571989,PubMed,10.1128/IAI.00162-20,Infect Immun. 2020 Aug 19;88(9):e00162-20. doi: 10.1128/IAI.00162-20. Print 2020 Aug 19,ruth.massey@bristol.ac.uk,Inactivation of mspA protein resulted in the loss of the ability of S. aureus to secrete cytolytic toxins.,S Duggan 2020,2020,2 genes,Duggan-2020-A Small Membrane Stabilizing Prote,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17080,PHI:10785,UniProt,no data found,GenBank,CBI50258,,,TW20,MspA,,,,,,,1280,Staphylococcus aureus,,SH1000,subcutaneous infection,primates,9606,Homo sapiens (related: human),,,,blood,small membrane-bound protein,,,,reduced virulence,,,,,,,,,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,YVS,32571989,PubMed,10.1128/IAI.00162-20,Infect Immun. 2020 Aug 19;88(9):e00162-20. doi: 10.1128/IAI.00162-20. Print 2020 Aug 19,ruth.massey@bristol.ac.uk,Inactivation of mspA protein resulted in the loss of the ability of S. aureus to secrete cytolytic toxins.,S Duggan 2020,2020,2 genes,Duggan-2020-A Small Membrane Stabilizing Prote,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17081,PHI:10787,UniProt,F9XG93,GenBank,EGP85749,,,IPO323,ZtSof1 (Mycgr3G74194),chromosome 7,,,,,,1047171,Zymoseptoria tritici,1276532,ST99CH_1E4,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Drifter,,,leaf,WW domain-containing protein,,,,unaffected pathogenicity,,,no,,,reduced,,aberrant,,no,NaCl; sorbitol; calcofluor white; Congo red; H2O2; SDS,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation; gene complementation,,,YVS,32782023,PubMed,10.1186/s12915-020-00838-9,BMC Biol. 2020 Aug 11;18(1):99. doi: 10.1186/s12915-020-00838-9,carolina.sardinha@usys.ethz.ch,The ΔZtSof1 mutant was severely impaired in melanization.,C S Francisco 2020,2020,2 genes,Francisco-2020-The role of vegetative cell fus,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17082,PHI:10788,UniProt,F9X7N2,GenBank,EGP88672,,,IPO323,ZtKu70,chromosome 3,,,,,,1047171,Zymoseptoria tritici,1276532,ST99CH_1E4,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Drifter,,,leaf,ATP-dependent DNA helicase II subunit 1,,,,unaffected pathogenicity,,,no,,,reduced,,aberrant,,no,NaCl; sorbitol; calcofluor white; Congo red; H2O2; SDS,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene mutation; gene complementation,,,YVS,32782023,PubMed,10.1186/s12915-020-00838-9,BMC Biol. 2020 Aug 11;18(1):99. doi: 10.1186/s12915-020-00838-9,carolina.sardinha@usys.ethz.ch,The ΔZtSof1 mutant was severely impaired in melanization.,C S Francisco 2020,2020,2 genes,Francisco-2020-The role of vegetative cell fus,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17083,PHI:10789,UniProt,Q2YPA3,GenBank,CAJ10226,,,2308,BAB1_0270,chromosome I,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,zinc-dependent metalloproteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32765455,PubMed,10.3389/fmicb.2020.01586,Front Microbiol. 2020 Jul 17;11:1586. doi: 10.3389/fmicb.2020.01586. eCollection 2020,aonate@udec.cl,"Deletion of BAB1_0270 significantly reduced the ability of B. abortus 1270 to adapt, grow and express several virulence factors under acidic conditions.",L A Gómez 2020,2020,1 gene,Gomez-2020-A Zinc-Dependent Metalloproteinase,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17084,PHI:10790,UniProt,P33883,GenBank,AAA25875,,,PAO1,lasI,,,,,,PHI:10791,287,Pseudomonas aeruginosa,208964,PAO1,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,acyl-homoserine-lactone synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; chemical complementation,,,YVS,32556478,PubMed,10.1007/s00284-020-02083-3,Curr Microbiol. 2020 Sep;77(9):2535-2543. doi: 10.1007/s00284-020-02083-3. Epub 2020 Jun 15,martha.ramirez@umich.mx,"PumA transfer did not increase bacterial virulence in lettuce and Caenorhabditis elegans, suggesting that the virulence conferred by PumA requires QS modulation.",K C Hernández-Ramírez 2020,2020,2 genes,Hernández-Ramír-2020-Virulence Conferred by Pu,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17085,PHI:10791,UniProt,P54291,GenBank,AAA82725,,,DSM2659,rhlI,,,,,,PHI:10790,287,Pseudomonas aeruginosa,208964,PAO1,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,putative autoinducer synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; chemical complementation,,,YVS,32556478,PubMed,10.1007/s00284-020-02083-3,Curr Microbiol. 2020 Sep;77(9):2535-2543. doi: 10.1007/s00284-020-02083-3. Epub 2020 Jun 15,martha.ramirez@umich.mx,"PumA transfer did not increase bacterial virulence in lettuce and Caenorhabditis elegans, suggesting that the virulence conferred by PumA requires QS modulation.",K C Hernández-Ramírez 2020,2020,2 genes,Hernández-Ramír-2020-Virulence Conferred by Pu,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17086,PHI:10790,UniProt,P33883,GenBank,AAA25875,,,PAO1,lasI,,,,,,PHI:10791,287,Pseudomonas aeruginosa,208964,PAO1,opportunistic infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,acyl-homoserine-lactone synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; chemical complementation,,,YVS,32556478,PubMed,10.1007/s00284-020-02083-3,Curr Microbiol. 2020 Sep;77(9):2535-2543. doi: 10.1007/s00284-020-02083-3. Epub 2020 Jun 15,martha.ramirez@umich.mx,"PumA transfer did not increase bacterial virulence in lettuce and Caenorhabditis elegans, suggesting that the virulence conferred by PumA requires QS modulation.",K C Hernández-Ramírez 2020,2020,2 genes,Hernández-Ramír-2020-Virulence Conferred by Pu,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17087,PHI:10791,UniProt,P54291,GenBank,AAA82725,,,DSM2659,rhlI,,,,,,PHI:10790,287,Pseudomonas aeruginosa,208964,PAO1,opportunistic infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,putative autoinducer synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; chemical complementation,,,YVS,32556478,PubMed,10.1007/s00284-020-02083-3,Curr Microbiol. 2020 Sep;77(9):2535-2543. doi: 10.1007/s00284-020-02083-3. Epub 2020 Jun 15,martha.ramirez@umich.mx,"PumA transfer did not increase bacterial virulence in lettuce and Caenorhabditis elegans, suggesting that the virulence conferred by PumA requires QS modulation.",K C Hernández-Ramírez 2020,2020,2 genes,Hernández-Ramír-2020-Virulence Conferred by Pu,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17088,PHI:10792,UniProt,A0A061L181,GenBank,AJO87020,,,MNCRE44,cjrA,,,,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,primates,9606,Homo sapiens (related: human),,,,serum,iron-regulated protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32762693,PubMed,10.1186/s12929-020-00677-4,J Biomed Sci. 2020 Aug 6;27(1):86. doi: 10.1186/s12929-020-00677-4,chteng@mail.ncku.edu.tw,Deletion of cjrABC-senB increased ExPEC's ability to cause bacteremia.,W C Huang 2020,2020,4 genes,Huang-2020-cjrABC-senB hinders survival of ext,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17089,PHI:10793,UniProt,C8CGJ1,GenBank,ACU68761,,,EC14,cjrB,,,,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,primates,9606,Homo sapiens (related: human),,,,serum,colicin Js sensitivity protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32762693,PubMed,10.1186/s12929-020-00677-4,J Biomed Sci. 2020 Aug 6;27(1):86. doi: 10.1186/s12929-020-00677-4,chteng@mail.ncku.edu.tw,Deletion of cjrABC-senB increased ExPEC's ability to cause bacteremia.,W C Huang 2020,2020,4 genes,Huang-2020-cjrABC-senB hinders survival of ext,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17090,PHI:10794,UniProt,C8CGJ2,GenBank,ACU68762,,,EC14,cjrC,,,,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,primates,9606,Homo sapiens (related: human),,,,serum,TonB-dependent colicin J protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32762693,PubMed,10.1186/s12929-020-00677-4,J Biomed Sci. 2020 Aug 6;27(1):86. doi: 10.1186/s12929-020-00677-4,chteng@mail.ncku.edu.tw,Deletion of cjrABC-senB increased ExPEC's ability to cause bacteremia.,W C Huang 2020,2020,4 genes,Huang-2020-cjrABC-senB hinders survival of ext,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17091,PHI:10795,UniProt,A0A0G9G3A2,GenBank,ANZ22158,,,ECwhn14,senB,,,,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,primates,9606,Homo sapiens (related: human),,,,serum,enterotoxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32762693,PubMed,10.1186/s12929-020-00677-4,J Biomed Sci. 2020 Aug 6;27(1):86. doi: 10.1186/s12929-020-00677-4,chteng@mail.ncku.edu.tw,Deletion of cjrABC-senB increased ExPEC's ability to cause bacteremia.,W C Huang 2020,2020,4 genes,Huang-2020-cjrABC-senB hinders survival of ext,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17092,PHI:10792,UniProt,A0A061L181,GenBank,AJO87020,,,MNCRE44,cjrA,,,,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),,,,blood,iron-regulated protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32762693,PubMed,10.1186/s12929-020-00677-4,J Biomed Sci. 2020 Aug 6;27(1):86. doi: 10.1186/s12929-020-00677-4,chteng@mail.ncku.edu.tw,Deletion of cjrABC-senB increased ExPEC's ability to cause bacteremia.,W C Huang 2020,2020,4 genes,Huang-2020-cjrABC-senB hinders survival of ext,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17093,PHI:10793,UniProt,C8CGJ1,GenBank,ACU68761,,,EC14,cjrB,,,,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),,,,blood,colicin Js sensitivity protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32762693,PubMed,10.1186/s12929-020-00677-4,J Biomed Sci. 2020 Aug 6;27(1):86. doi: 10.1186/s12929-020-00677-4,chteng@mail.ncku.edu.tw,Deletion of cjrABC-senB increased ExPEC's ability to cause bacteremia.,W C Huang 2020,2020,4 genes,Huang-2020-cjrABC-senB hinders survival of ext,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17094,PHI:10794,UniProt,C8CGJ2,GenBank,ACU68762,,,EC14,cjrC,,,,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),,,,blood,TonB-dependent colicin J protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32762693,PubMed,10.1186/s12929-020-00677-4,J Biomed Sci. 2020 Aug 6;27(1):86. doi: 10.1186/s12929-020-00677-4,chteng@mail.ncku.edu.tw,Deletion of cjrABC-senB increased ExPEC's ability to cause bacteremia.,W C Huang 2020,2020,4 genes,Huang-2020-cjrABC-senB hinders survival of ext,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17095,PHI:10795,UniProt,A0A0G9G3A2,GenBank,ANZ22158,,,ECwhn14,senB,,,,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),,,,blood,enterotoxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32762693,PubMed,10.1186/s12929-020-00677-4,J Biomed Sci. 2020 Aug 6;27(1):86. doi: 10.1186/s12929-020-00677-4,chteng@mail.ncku.edu.tw,Deletion of cjrABC-senB increased ExPEC's ability to cause bacteremia.,W C Huang 2020,2020,4 genes,Huang-2020-cjrABC-senB hinders survival of ext,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17096,PHI:10796,UniProt,G7TD81,GenBank,AEQ95027,,,BLS256,xopI,,,,,,,347,Xanthomonas oryzae,,pv. oryzae strain BAI3,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32881160,PubMed,10.1111/tpj.14980,Plant J. 2020 Sep 3. doi: 10.1111/tpj.14980. Online ahead of print,zongyunli@jsnu.edu.cn,The xopI knockout mutant displays lower virulence to rice than BAI3. Host gene alteration data available for OsTrxh2,H Ji 2020,2020,1 gene,Ji-2020-A bacterial F-box effector suppresses,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17097,PHI:10797,UniProt,Q3YJR5,GenBank,ADH04593,,,RH,ROP16,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,rhoptry protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32767999,PubMed,10.1186/s13071-020-04251-7,Parasit Vectors. 2020 Aug 7;13(1):400. doi: 10.1186/s13071-020-04251-7,floriapeng@hotmail.com,"Immune-related receptor protein IL20RB was targeted by TgROP18 upon T. gondii invasion, and led to synergic activation of the host JAK/STAT3 pathway together with TgROP16, triggering proinflammatory immune responses against T. gondii.",L Kong 2020,2020,2 genes,Kong-2020-TgROP18 targets IL20RB for host-defe,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17098,PHI:10798,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,ROP18,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,serine/threonine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32767999,PubMed,10.1186/s13071-020-04251-7,Parasit Vectors. 2020 Aug 7;13(1):400. doi: 10.1186/s13071-020-04251-7,floriapeng@hotmail.com,"Immune-related receptor protein IL20RB was targeted by TgROP18 upon T. gondii invasion, and led to synergic activation of the host JAK/STAT3 pathway together with TgROP16, triggering proinflammatory immune responses against T. gondii.",L Kong 2020,2020,2 genes,Kong-2020-TgROP18 targets IL20RB for host-defe,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17099,PHI:10797,UniProt,Q3YJR5,GenBank,ADH04593,,,RH,ROP16,,,,,,PHI:10798,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,rhoptry protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32767999,PubMed,10.1186/s13071-020-04251-7,Parasit Vectors. 2020 Aug 7;13(1):400. doi: 10.1186/s13071-020-04251-7,floriapeng@hotmail.com,"Immune-related receptor protein IL20RB was targeted by TgROP18 upon T. gondii invasion, and led to synergic activation of the host JAK/STAT3 pathway together with TgROP16, triggering proinflammatory immune responses against T. gondii.",L Kong 2020,2020,2 genes,Kong-2020-TgROP18 targets IL20RB for host-defe,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17100,PHI:10798,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,ROP18,,,,,,PHI:10797,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,serine/threonine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32767999,PubMed,10.1186/s13071-020-04251-7,Parasit Vectors. 2020 Aug 7;13(1):400. doi: 10.1186/s13071-020-04251-7,floriapeng@hotmail.com,"Immune-related receptor protein IL20RB was targeted by TgROP18 upon T. gondii invasion, and led to synergic activation of the host JAK/STAT3 pathway together with TgROP16, triggering proinflammatory immune responses against T. gondii.",L Kong 2020,2020,2 genes,Kong-2020-TgROP18 targets IL20RB for host-defe,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17101,PHI:10799,,no data found,,,,,,gla1,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17102,PHI:10800,,no data found,,,,,,cbd1,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17103,PHI:10801,,no data found,,,,,,amy1,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17104,PHI:10802,,no data found,,,,,,mep2,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17105,PHI:10803,UniProt,G2WYR8,GenBank,EGY21720,,,VdLs.17,mep1,chromosome 6,,,,,PHI:10802,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,ammonium transporter MEP1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17106,PHI:10802,,no data found,,,,,,mep2,,,,,,PHI:10803,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17107,PHI:10804,,no data found,,,,,,cp1,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17108,PHI:10805,UniProt,G2WV28,GenBank,EGY20153,,,VdLs.17,cp2,chromosome 7,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,CP2 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17109,PHI:10804,,no data found,,,,,,cp1,,,,,,PHI:10805,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17110,PHI:10805,UniProt,G2WV28,GenBank,EGY20153,,,VdLs.17,cp2,chromosome 7,,,,,PHI:10804,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,CP2 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17111,PHI:10806,,no data found,,,,,,nlp2,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17112,PHI:10807,,no data found,,,,,,nlp3,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17113,PHI:10806,,no data found,,,,,,nlp2,,,,,,PHI:10807,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17114,PHI:10807,,no data found,,,,,,nlp3,,,,,,PHI:10806,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17115,PHI:10803,UniProt,G2WYR8,GenBank,EGY21720,,,VdLs.17,mep1,chromosome 6,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,ammonium transporter MEP1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17116,PHI:10807,,no data found,,,,,,nlp3,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,root,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849460,PubMed,10.3389/fmicb.2020.01876,Front Microbiol. 2020 Aug 6;11:1876. doi: 10.3389/fmicb.2020.01876. eCollection 2020,gbraus@gwdg.de,The xylem sap-specific exoproteome pinpointed Nlp2 and Nlp3 as single effectors required for successful V. dahliae colonization.,M Leonard 2020,2020,9 genes,Leonard-2020-Verticillium longisporum Elicits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17117,PHI:10808,,no data found,GenBank,QOE31016,,,10,metQ,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative D-methionine-binding lipoprotein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17118,PHI:10809,UniProt,A0A0K2E6P6,GenBank,ANC99504,,,DN13,walR,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,DNA-binding response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17119,PHI:10808,,no data found,GenBank,QOE31016,,,10,metQ,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative D-methionine-binding lipoprotein MetQ,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17120,PHI:10809,UniProt,A0A0K2E6P6,GenBank,ANC99504,,,DN13,walR,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,DNA-binding response regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17121,PHI:10810,,no data found,GenBank,AKG39626,,,ZY05719,HP1065 (ZY05719_01065),,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17122,PHI:10811,,no data found,GenBank,AKG41355,,,ZY05719,LysM2173 (ZY05719_10260),,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,peptidoglycan-binding protein LysM,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17123,PHI:10812,,no data found,GenBank,AKG39867,,,ZY05719,ZY05719_02410,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"ribose 5-phosphate isomerase, rpiA",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17124,PHI:10813,,no data found,GenBank,AKG40114,,,ZY05719,ZY05719_03765,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,branched-chain amino acid ABC transport substrate binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17125,PHI:10814,,no data found,GenBank,AKG40608,,,ZY05719,ZY05719_06345,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"S-transferase, GST",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17126,PHI:10815,,no data found,GenBank,AKG40374,,,ZY05719,ZY05719_05150,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"ribose-phosphate pyrophosphokinase, prs",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17127,PHI:10816,,no data found,GenBank,AKG40047,,,ZY05719,ZY05719_03375,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"type I restriction-modification system, DNA methylase subunit, HsdM",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17128,PHI:10817,,no data found,GenBank,AKG40901,,,ZY05720,ZY05719_07905,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"response regulator transcription factor, WalR",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17129,PHI:10818,,no data found,GenBank,AKG40092,,,ZY05721,ZY05719_03620,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,ABC transporter permease/hypothetical protein with unknown function,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17130,PHI:10819,,no data found,GenBank,AKG41002,,,ZY05722,ZY05719_08420,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,MetQ/NlpA family ABC transporter substrate binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17131,PHI:10820,,no data found,GenBank,AKG39939,,,ZY05723,ZY05719_02775,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"glycosyltransferase family 1 protein, Cps2F",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17132,PHI:10821,,no data found,GenBank,AKG40448,,,ZY05724,ZY05719_05530,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,GNAT family N-acetyltransferase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17133,PHI:10822,,no data found,GenBank,AKG40662,,,ZY05725,ZY05719_06620,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,SAM-dependent methyltransferase TehB,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17134,PHI:10823,,no data found,GenBank,AKG39927,,,ZY05726,ZY05719_02715,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"glutamate 5-kinase, proB",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17135,PHI:10824,,no data found,GenBank,AKG39711,,,ZY05727,ZY05719_01510,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,heat shock protein DnaK,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17136,PHI:10817,,no data found,GenBank,AKG40901,,,ZY05728,ZY05719_07905,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,"response regulator transcription factor, WalR",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17137,PHI:10819,,no data found,GenBank,AKG41002,,,ZY05729,ZY05719_08420,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,MetQ/NlpA family ABC transporter substrate binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17138,PHI:10813,,no data found,GenBank,AKG40114,,,ZY05730,ZY05719_03765,,,,,,,1307,Streptococcus suis,,ZY05719,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),,,,blood,branched-chain amino acid ABC transport substrate binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,32614642,PubMed,10.1080/21505594.2020.1782088,Virulence. 2020 Dec;11(1):825-838. doi: 10.1080/21505594.2020.1782088,fhj@njau.edu.cn,The survival ability in macrophages and whole blood of randomly picked mutant strains were significantly impaired compared with wild-type ZY05719 and the virulence of the mutant strains was also attenuated in a mouse infection model.,X Pei 2020,2020,17 genes,Pei-2020-Screening for phagocytosis resistance,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17139,PHI:10825,UniProt,C1FZQ7,GenBank,EEH43808,,,Pb18,sidA (PADG_00097),,,,,,,121759,Paracoccidioides brasiliensis,502780,Pb18,paracoccidioidomycosis,beetles,7067,Tenebrio molitor (related: yellow mealworm),,,,larva,L-ornithine N(5)-monooxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,32742914,PubMed,10.1186/s43008-020-00035-x,IMA Fungus. 2020 Jun 29;11:11. doi: 10.1186/s43008-020-00035-x. eCollection 2020,cmasoares@gmail.com,The obtained AsSidA strains displayed decreased siderophore biosynthesis in iron deprivation conditions and reduced virulence to an invertebrate model.,M G Silva 2020,2020,1 gene,Silva-2020-Molecular characterization of sider,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17140,PHI:10826,UniProt,A0A1B5KZM5,GenBank,GAO16575,,,IPU010,UvHrip1 (UVI_02019870),,,,,,,1159556,Ustilaginoidea virens,,P1,false smut (rice),eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,32566413,PubMed,10.7717/peerj.9354,PeerJ. 2020 Jun 12;8:e9354. doi: 10.7717/peerj.9354. eCollection 2020,shw@syau.edu.cn,UvHrip1 suppressed the mammalian BAX-induced necrosis-like defense symptoms in N. benthamiana.,Y Wang 2020,2020,1 gene,Wang-2020-A putative effector UvHrip1 inhibits,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17141,PHI:10827,UniProt,Q7CWA3,GenBank,AAK88486,,,C58,bfr (atu2771),,,,,,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,23013,Kalanchoe daigremontiana (related: devil's backbone),,,,leaf,bacterioferritin,,,,reduced virulence,,,,,,,,,,no,H2O2; FeSO4,H2O2: CHEBI:16240; FeSO4: CHEBI:75832,,,,,gene deletion: full; gene complementation,,,YVS,32678502,PubMed,10.1111/mpp.12969,Mol Plant Pathol. 2020 Sep;21(9):1167-1178. doi: 10.1111/mpp.12969. Epub 2020 Jul 17,guoml@yzu.edu.cn,The tumour induced by each of three ferritin-deficient mutants is less than that of the wild type.,J Yang 2020,2020,2 genes,Yang-2020-Agrobacterium tumefaciens ferritins,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17142,PHI:10828,UniProt,Q8UCK6,GenBank,AAK88212,,,C58,dps (atu2477),,,,,,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,23013,Kalanchoe daigremontiana (related: devil's backbone),,,,leaf,DNA protection during starvation protein,,,,reduced virulence,,,,,,,,,,no,H2O2; FeSO4,H2O2: CHEBI:16240; FeSO4: CHEBI:75832,,,,,gene deletion: full; gene complementation,,,YVS,32678502,PubMed,10.1111/mpp.12969,Mol Plant Pathol. 2020 Sep;21(9):1167-1178. doi: 10.1111/mpp.12969. Epub 2020 Jul 17,guoml@yzu.edu.cn,The tumour induced by each of three ferritin-deficient mutants is less than that of the wild type.,J Yang 2020,2020,2 genes,Yang-2020-Agrobacterium tumefaciens ferritins,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17143,PHI:10827,UniProt,Q7CWA3,GenBank,AAK88486,,,C58,bfr (atu2771),,,,,,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,bacterioferritin,,,,reduced virulence,,,,,,,,,,no,H2O2; FeSO4,H2O2: CHEBI:16240; FeSO4: CHEBI:75832,,,,,gene deletion: full; gene complementation,,,YVS,32678502,PubMed,10.1111/mpp.12969,Mol Plant Pathol. 2020 Sep;21(9):1167-1178. doi: 10.1111/mpp.12969. Epub 2020 Jul 17,guoml@yzu.edu.cn,The tumour induced by each of three ferritin-deficient mutants is less than that of the wild type.,J Yang 2020,2020,2 genes,Yang-2020-Agrobacterium tumefaciens ferritins,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17144,PHI:10828,UniProt,Q8UCK6,GenBank,AAK88212,,,C58,dps (atu2477),,,,,,,358,Agrobacterium tumefaciens,,C58,crown gall,eudicots,4113,Solanum tuberosum (related: potato),cv. Qingshu9; cv. Longshu7,,,leaf,DNA protection during starvation protein,,,,reduced virulence,,,,,,,,,,no,H2O2; FeSO4,H2O2: CHEBI:16240; FeSO4: CHEBI:75832,,,,,gene deletion: full; gene complementation,,,YVS,32678502,PubMed,10.1111/mpp.12969,Mol Plant Pathol. 2020 Sep;21(9):1167-1178. doi: 10.1111/mpp.12969. Epub 2020 Jul 17,guoml@yzu.edu.cn,The tumour induced by each of three ferritin-deficient mutants is less than that of the wild type.,J Yang 2020,2020,2 genes,Yang-2020-Agrobacterium tumefaciens ferritins,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17145,PHI:10829,UniProt,A0A0K0MJJ9,GenBank,AKE48503,,,UVas1-58,MAT1-1-1,,,,MAT1-1-2,UniProt: A0A0K0MK68; GenBank: AKE48502,,1159556,Ustilaginoidea virens,,Uv2-51,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Liangyoupeijiu,,,leaf,mating type protein,,,,unaffected pathogenicity,,,,,,aberrant,,reduced,,no,NaCl; sorbitol; H2O2; CR; CFW; SDS,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32572596,PubMed,10.1007/s00294-020-01085-9,Curr Genet. 2020 Oct;66(5):989-1002. doi: 10.1007/s00294-020-01085-9. Epub 2020 Jun 22,liuyf@jaas.ac.cn,"Targeted deletion of MAT1-1-2 not only impaired the sclerotia formation and pathogenicity of V. virens, but also reduced the production of conidia.",M Yong 2020,2020,2 genes,Yong-2020-Two mating-type genes MAT1-1-1 and M,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17146,PHI:10830,UniProt,A0A0K0MK68,GenBank,AKE48502,,,UVas1-58,MAT1-1-2,,,,MAT1-1-1,UniProt: A0A0K0MJJ9; GenBank: AKE48503,,1159556,Ustilaginoidea virens,,Uv2-51,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Liangyoupeijiu,,,leaf,mating type protein,,,,reduced virulence,,,,,,reduced,reduced,wild type,,no,NaCl; sorbitol; H2O2; CR; CFW; SDS,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32572596,PubMed,10.1007/s00294-020-01085-9,Curr Genet. 2020 Oct;66(5):989-1002. doi: 10.1007/s00294-020-01085-9. Epub 2020 Jun 22,liuyf@jaas.ac.cn,"Targeted deletion of MAT1-1-2 not only impaired the sclerotia formation and pathogenicity of V. virens, but also reduced the production of conidia.",M Yong 2020,2020,2 genes,Yong-2020-Two mating-type genes MAT1-1-1 and M,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17147,PHI:10831,UniProt,J4WLW2,GenBank,EJP70705,,,ARSEF 2860,sur7,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,eisosome protein,,,,reduced virulence,,,,,,,,reduced,reduced,no,Congo red; SDS; calcofluor white; NaCl; sorbitol; H2O2; caspofungin,Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,32548688,PubMed,10.1007/s00253-020-10736-3,Appl Microbiol Biotechnol. 2020 Aug;104(15):6669-6678. doi: 10.1007/s00253-020-10736-3. Epub 2020 Jun 16,mgfeng@zju.edu.cn,"Deletion of sur7 resulted in reduced conidiation capacity and impaired conidial quality, which was featured by slower germination, attenuated virulence, and reduced carbohydrate epitopes (ß-N-acetylglucosamine and sialic acids).",L B Zhang 2020,2020,1 gene,Zhang-2020-Subcellular localization of Sur7 an,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17148,PHI:10832,UniProt,no data found,GenBank,,,,,brd4,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,BET family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32541671,PubMed,10.1038/s41419-020-2672-0,Cell Death Dis. 2020 Jun 15;11(6):459. doi: 10.1038/s41419-020-2672-0,wangyi83@scu.edu.cn,BRD4 knock-down increased macrophage survival through interrupted RNS production.,F Zhu 2020,2020,1 gene,Zhu-2020-Brd4 inhibition ameliorates Pyocyanin,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17149,PHI:10846,UniProt,Q8XZK9,GenBank,CAD15088,,,GMI1000,RSc1386,,,,,,PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17150,PHI:10847,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,PHI:10846; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17151,PHI:10848,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,PHI:10846; PHI:10847,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17152,PHI:10840,UniProt,Q8XTZ4,GenBank,CAD16898,,,GMI1000,RSc3401,,,,,,PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17153,PHI:10841,UniProt,Q8XQB2,GenBank,CAD18525,,,GMI1000,RSp1374,,,,,,PHI:10840; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17154,PHI:10842,UniProt,Q3IZC2,GenBank,CAD18525,,,GMI1000,RSp0930,,,,,,PHI:10840; PHI:10841; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17155,PHI:10843,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,PHI:10840; PHI:10841; PHI:10842; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17156,PHI:10844,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17157,PHI:10845,UniProt,Q8XXI4,GenBank,CAD15837,,,GMI1000,RSc2130,,,,,,PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17158,PHI:10833,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17159,PHI:10834,UniProt,Q3J038,GenBank,CAD17823,,,GMI1000,RSp0672,,,,,,PHI:10833; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17160,PHI:10835,UniProt,Q3J1Y8,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,PHI:10833; PHI:10834; PHI:10836; PHI:10837; PHI:10838; PHI:10839,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17161,PHI:10836,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10837; PHI:10838; PHI:10839,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17162,PHI:10837,UniProt,Q8XYF7,GenBank,CAD15502,,,GMI1000,RSc1801,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10838; PHI:10839,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17163,PHI:10838,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10839,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17164,PHI:10839,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17165,PHI:10849,UniProt,Q8XXH5,GenBank,CAD15846,,,GMI1000,RSc2139,,,,,,PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17166,PHI:10850,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,PHI:10849; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17167,PHI:10851,UniProt,Q8XRI5,GenBank,CAD17997,,,GMI1000,RSp0846,,,,,,PHI:10849; PHI:10850; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17168,PHI:10852,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,PHI:10849; PHI:10850; PHI:10851; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17169,PHI:10853,UniProt,Q8XR44,GenBank,CAD18175,,,GMI1000,RSp1024,,,,,,PHI:10849; PHI:10850; PHI:10851; PHI:10852,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17170,PHI:10833,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17171,PHI:10834,UniProt,Q3J038,GenBank,CAD17823,,,GMI1000,RSp0672,,,,,,PHI:10833; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17172,PHI:10835,UniProt,Q3J1Y8,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,PHI:10833; PHI:10834; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17173,PHI:10836,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17174,PHI:10837,UniProt,Q8XYF7,GenBank,CAD15502,,,GMI1000,RSc1801,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17175,PHI:10838,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17176,PHI:10839,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17177,PHI:10840,UniProt,Q8XTZ4,GenBank,CAD16898,,,GMI1000,RSc3401,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17178,PHI:10841,UniProt,Q8XQB2,GenBank,CAD18525,,,GMI1000,RSp1374,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10842; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17179,PHI:10842,UniProt,Q3IZC2,GenBank,CAD18525,,,GMI1000,RSp0930,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10843; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17180,PHI:10843,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10844; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17181,PHI:10844,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10845,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17182,PHI:10845,UniProt,Q8XXI4,GenBank,CAD15837,,,GMI1000,RSc2130,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17183,PHI:10833,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17184,PHI:10834,UniProt,Q3J038,GenBank,CAD17823,,,GMI1000,RSp0672,,,,,,PHI:10833; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17185,PHI:10835,UniProt,Q3J1Y8,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,PHI:10833; PHI:10834; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17186,PHI:10836,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17187,PHI:10837,UniProt,Q8XYF7,GenBank,CAD15502,,,GMI1000,RSc1801,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17188,PHI:10838,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17189,PHI:10839,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17190,PHI:10840,UniProt,Q8XTZ4,GenBank,CAD16898,,,GMI1000,RSc3401,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17191,PHI:10841,UniProt,Q8XQB2,GenBank,CAD18525,,,GMI1000,RSp1374,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17192,PHI:10842,UniProt,Q3IZC2,GenBank,CAD18525,,,GMI1000,RSp0930,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17193,PHI:10843,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17194,PHI:10844,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10845; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17195,PHI:10845,UniProt,Q8XXI4,GenBank,CAD15837,,,GMI1000,RSc2130,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10846; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17196,PHI:10846,UniProt,Q8XZK9,GenBank,CAD15088,,,GMI1000,RSc1386,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10847; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17197,PHI:10847,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10848,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17198,PHI:10848,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17199,PHI:10833,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17200,PHI:10834,UniProt,Q3J038,GenBank,CAD17823,,,GMI1000,RSp0672,,,,,,PHI:10833; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17201,PHI:10835,UniProt,Q3J1Y8,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,PHI:10833; PHI:10834; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17202,PHI:10836,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17203,PHI:10837,UniProt,Q8XYF7,GenBank,CAD15502,,,GMI1000,RSc1801,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17204,PHI:10838,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17205,PHI:10839,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17206,PHI:10840,UniProt,Q8XTZ4,GenBank,CAD16898,,,GMI1000,RSc3401,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17207,PHI:10841,UniProt,Q8XQB2,GenBank,CAD18525,,,GMI1000,RSp1374,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17208,PHI:10842,UniProt,Q3IZC2,GenBank,CAD18525,,,GMI1000,RSp0930,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17209,PHI:10843,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17210,PHI:10844,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17211,PHI:10845,UniProt,Q8XXI4,GenBank,CAD15837,,,GMI1000,RSc2130,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17212,PHI:10846,UniProt,Q8XZK9,GenBank,CAD15088,,,GMI1000,RSc1386,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17213,PHI:10847,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17214,PHI:10848,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17215,PHI:10849,UniProt,Q8XXH5,GenBank,CAD15846,,,GMI1000,RSc2139,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10850; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17216,PHI:10850,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10851; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17217,PHI:10851,UniProt,Q8XRI5,GenBank,CAD17997,,,GMI1000,RSp0846,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10852; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17218,PHI:10852,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10853,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17219,PHI:10853,UniProt,Q8XR44,GenBank,CAD18175,,,GMI1000,RSp1024,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17220,PHI:10833,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17221,PHI:10834,UniProt,Q3J038,GenBank,CAD17823,,,GMI1000,RSp0672,,,,,,PHI:10833; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17222,PHI:10835,UniProt,Q3J1Y8,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,PHI:10833; PHI:10834; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17223,PHI:10836,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17224,PHI:10837,UniProt,Q8XYF7,GenBank,CAD15502,,,GMI1000,RSc1801,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17225,PHI:10838,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17226,PHI:10839,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17227,PHI:10840,UniProt,Q8XTZ4,GenBank,CAD16898,,,GMI1000,RSc3401,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17228,PHI:10841,UniProt,Q8XQB2,GenBank,CAD18525,,,GMI1000,RSp1374,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17229,PHI:10842,UniProt,Q3IZC2,GenBank,CAD18525,,,GMI1000,RSp0930,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17230,PHI:10843,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17231,PHI:10844,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17232,PHI:10845,UniProt,Q8XXI4,GenBank,CAD15837,,,GMI1000,RSc2130,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17233,PHI:10846,UniProt,Q8XZK9,GenBank,CAD15088,,,GMI1000,RSc1386,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17234,PHI:10847,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17235,PHI:10848,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17236,PHI:10849,UniProt,Q8XXH5,GenBank,CAD15846,,,GMI1000,RSc2139,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17237,PHI:10850,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17238,PHI:10851,UniProt,Q8XRI5,GenBank,CAD17997,,,GMI1000,RSp0846,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17239,PHI:10852,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17240,PHI:10853,UniProt,Q8XR44,GenBank,CAD18175,,,GMI1000,RSp1024,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17241,PHI:10854,UniProt,Q8XRI6,GenBank,CAD17996,,,GMI1000,RSp0845,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17242,PHI:10855,UniProt,Q8Y2T7,GenBank,CAD13773,,,GMI1000,RSc0245,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17243,PHI:10856,UniProt,Q8XXL2,GenBank,CAD15808,,,GMI1000,RSc2101,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17244,PHI:10857,UniProt,Q8XVQ5,GenBank,CAD16482,,,GMI1000,RSc2775,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17245,PHI:10858,UniProt,Q8XU25,GenBank,CAD16866,,,GMI1000,RSc3369,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17246,PHI:10859,UniProt,Q8XT13,GenBank,CAD17455,,,GMI1000,RSp0304,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17247,PHI:10860,UniProt,Q8XRJ3,GenBank,CAD17989,,,GMI1000,RSp0838,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17248,PHI:10861,,no data found,,,,,,RSp087765,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17249,PHI:10862,UniProt,Q8XRH4,GenBank,CAD18030,,,GMI1000,RSp0879,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17250,PHI:10863,UniProt,Q8XR46,GenBank,CAD18173,,,GMI1000,RSp1022,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17251,PHI:10864,UniProt,Q8XR37,GenBank,CAD18182,,,GMI1000,RSp1031,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17252,PHI:10865,UniProt,Q8XQE6,GenBank,CAD18432,,,GMI1000,RSp1281,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17253,PHI:10866,UniProt,Q8XPN7,GenBank,CAD18752,,,GMI1000,RSp1601,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17254,PHI:10867,UniProt,Q8Y1T1,GenBank,CAD14138,,,GMI1000,RSc0608,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17255,PHI:10868,UniProt,Q8XUB9,GenBank,CAD17060,,,GMI1000,RSc3272,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17256,PHI:10869,UniProt,Q8XQI9,GenBank,CAD18387,,,GMI1000,RSp1236,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17257,PHI:10870,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17258,PHI:10871,UniProt,Q8XRG9,GenBank,CAD18036,,,GMI1000,RSp0885,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17259,PHI:10872,UniProt,Q8XZC6,GenBank,CAD15177,,,GMI1000,RSc1475,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17260,PHI:10833,UniProt,Q8XRE0,GenBank,CAD18065,,,GMI1000,RSp0914,,,,,,PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17261,PHI:10834,UniProt,Q3J038,GenBank,CAD17823,,,GMI1000,RSp0672,,,,,,PHI:10833; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17262,PHI:10835,UniProt,Q3J1Y8,GenBank,CAD17179,,,GMI1000,RSp0028,,,,,,PHI:10833; PHI:10834; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17263,PHI:10836,UniProt,Q8XYF8,GenBank,CAD15502,,,GMI1000,RSc1800,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17264,PHI:10837,UniProt,Q8XYF7,GenBank,CAD15502,,,GMI1000,RSc1801,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17265,PHI:10838,UniProt,Q8XZN9,GenBank,CAD15058,,,GMI1000,RSc1356,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17266,PHI:10839,UniProt,Q8XZN8,GenBank,CAD15059,,,GMI1000,RSc1357,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17267,PHI:10840,UniProt,Q8XTZ4,GenBank,CAD16898,,,GMI1000,RSc3401,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17268,PHI:10841,UniProt,Q8XQB2,GenBank,CAD18525,,,GMI1000,RSp1374,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17269,PHI:10842,UniProt,Q3IZC2,GenBank,CAD18525,,,GMI1000,RSp0930,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17270,PHI:10843,UniProt,Q8XYB9,GenBank,CAD15541,,,GMI1000,RSc1839,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17271,PHI:10844,UniProt,Q8XT19,GenBank,CAD17447,,,GMI1000,RSp0296,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17272,PHI:10845,UniProt,Q8XXI4,GenBank,CAD15837,,,GMI1000,RSc2130,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17273,PHI:10846,UniProt,Q8XZK9,GenBank,CAD15088,,,GMI1000,RSc1386,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17274,PHI:10847,UniProt,Q8XT99,GenBank,CAD17366,,,GMI1000,RSp0215,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17275,PHI:10848,UniProt,Q8XTF2,GenBank,CAD17311,,,GMI1000,RSp0160,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17276,PHI:10849,UniProt,Q8XXH5,GenBank,CAD15846,,,GMI1000,RSc2139,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17277,PHI:10850,UniProt,Q8XTK9,GenBank,CAD17250,,,GMI1000,RSp0099,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17278,PHI:10851,UniProt,Q8XRI5,GenBank,CAD17997,,,GMI1000,RSp0846,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17279,PHI:10852,UniProt,Q8XRI4,GenBank,CAD17998,,,GMI1000,RSp0847,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17280,PHI:10853,UniProt,Q8XR44,GenBank,CAD18175,,,GMI1000,RSp1024,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17281,PHI:10854,UniProt,Q8XRI6,GenBank,CAD17996,,,GMI1000,RSp0845,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17282,PHI:10855,UniProt,Q8Y2T7,GenBank,CAD13773,,,GMI1000,RSc0245,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17283,PHI:10856,UniProt,Q8XXL2,GenBank,CAD15808,,,GMI1000,RSc2101,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17284,PHI:10857,UniProt,Q8XVQ5,GenBank,CAD16482,,,GMI1000,RSc2775,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17285,PHI:10858,UniProt,Q8XU25,GenBank,CAD16866,,,GMI1000,RSc3369,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17286,PHI:10859,UniProt,Q8XT13,GenBank,CAD17455,,,GMI1000,RSp0304,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17287,PHI:10860,UniProt,Q8XRJ3,GenBank,CAD17989,,,GMI1000,RSp0838,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17288,PHI:10861,,no data found,,,,,,RSp087765,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17289,PHI:10862,UniProt,Q8XRH4,GenBank,CAD18030,,,GMI1000,RSp0879,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17290,PHI:10863,UniProt,Q8XR46,GenBank,CAD18173,,,GMI1000,RSp1022,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17291,PHI:10864,UniProt,Q8XR37,GenBank,CAD18182,,,GMI1000,RSp1031,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17292,PHI:10865,UniProt,Q8XQE6,GenBank,CAD18432,,,GMI1000,RSp1281,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17293,PHI:10866,UniProt,Q8XPN7,GenBank,CAD18752,,,GMI1000,RSp1601,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17294,PHI:10867,UniProt,Q8Y1T1,GenBank,CAD14138,,,GMI1000,RSc0608,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10868; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17295,PHI:10868,UniProt,Q8XUB9,GenBank,CAD17060,,,GMI1000,RSc3272,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10869; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17296,PHI:10869,UniProt,Q8XQI9,GenBank,CAD18387,,,GMI1000,RSp1236,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10870; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17297,PHI:10870,UniProt,Q8XQI6,GenBank,CAD18390,,,GMI1000,RSp1239,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10871; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17298,PHI:10871,UniProt,Q8XRG9,GenBank,CAD18036,,,GMI1000,RSp0885,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10872,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17299,PHI:10872,UniProt,Q8XZC6,GenBank,CAD15177,,,GMI1000,RSc1475,,,,,,PHI:10833; PHI:10834; PHI:10835; PHI:10836; PHI:10837; PHI:10838; PHI:10839; PHI:10840; PHI:10841; PHI:10842; PHI:10843; PHI:10844; PHI:10845; PHI:10846; PHI:10847; PHI:10848; PHI:10849; PHI:10850; PHI:10851; PHI:10852; PHI:10853; PHI:10854; PHI:10855; PHI:10856; PHI:10857; PHI:10858; PHI:10859; PHI:10860; PHI:10861; PHI:10862; PHI:10863; PHI:10864; PHI:10865; PHI:10866; PHI:10867; PHI:10868; PHI:10869; PHI:10870; PHI:10871,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32849353,PubMed,10.3389/fmicb.2020.01683,Front Microbiol. 2020 Jul 30;11:1683. doi: 10.3389/fmicb.2020.01683. eCollection 2020,kouheio@kochi-u.ac.jp,All the core and extended core T3Es are nearly crucial for virulence of OE1-1 toward host plants.,N Lei 2020,2020,40 genes,Lei-2020-Super-Multiple Deletion Analysis of T,BATCH_102C,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17300,PHI:10873,UniProt,Q4WUM2,GenBank,EAL91704,,,Af293,rsrA (Afu5g08950),chromosome 5,,,,,,746128,Aspergillus fumigatus,1266464,CEA17 (Δku80 ΔpyrG),pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,RAS small monomeric GTPase,,,,reduced virulence,,,,,,,,reduced,reduced,no,calcofluor white; congo red; NaCl; KCl; sorbitol; hydrogen peroxide; voriconazole,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; hydrogen peroxide: CHEBI:16240; voriconazole: CHEBI:10023,,,,,gene deletion: full; gene complementation,,,YVS,33202962,PubMed,10.3390/jof6040285,J Fungi (Basel). 2020 Nov 13;6(4):E285,wge@uthsc.edu,"Overexpression of rsrA resulted in a morphogenesis defect, characterized by a significant delay in polarity establishment followed by the establishment of multiple growth axes.",A Martin-Vicente 2020,2020,1 gene,Martin-Vicente-2020-Overexpression of the Aspe,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17301,PHI:10874,UniProt,G4N713,GenBank,EHA49926,,,70-15,MoSec61beta (MGG_03644),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,hypothetical protein,,,,reduced virulence,,,yes,,,,,reduced,,no,CFW; Congo red (CR); SDS,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,33200669,PubMed,10.1080/21505594.2020.1848983,Virulence. 2020 Nov 17,fuchenglin@zju.edu.cn,"ΔMosec61beta mutant exhibited highly branched mycelial morphology, reduced conidiation, high sensitivity to cell wall integrity stress, severely reduced virulence to rice and barley, and restricted biotrophic invasion.",Y Y Wei 2020,2020,1 gene,"Wei-2020-MoSec61β, the beta subunit of Sec61",BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17302,PHI:10874,UniProt,G4N713,GenBank,EHA49926,,,70-15,MoSec61beta (MGG_03644),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,reduced virulence,,,yes,,,,,reduced,,no,CFW; Congo red (CR); SDS,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,33200669,PubMed,10.1080/21505594.2020.1848983,Virulence. 2020 Nov 17,fuchenglin@zju.edu.cn,"ΔMosec61beta mutant exhibited highly branched mycelial morphology, reduced conidiation, high sensitivity to cell wall integrity stress, severely reduced virulence to rice and barley, and restricted biotrophic invasion.",Y Y Wei 2020,2020,1 gene,"Wei-2020-MoSec61β, the beta subunit of Sec61",BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17303,PHI:10875,UniProt,A0A0H3LHY6,GenBank,CAE31262,,,RB50,HK2 (BB0763),,,,,,,139,Borreliella burgdorferi,,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin; heart; joint,enoyl CoA dehydratase/isomerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33195322,PubMed,10.3389/fmed.2020.573648,Front Med (Lausanne). 2020 Oct 26;7:573648,lyl@wmu.edu.cn,"HK2 was not required for spirochetal survival in the tick vector, but when fed on naive mice, the hk2 mutant had reduced infectivity through the route of tick bite.",Q Liu 2020,2020,1 gene,Liu-2020-Role of HK2 in the Enzootic Cycle of,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17304,PHI:10875,UniProt,A0A0H3LHY6,GenBank,CAE31262,,,RB50,HK2 (BB0763),,,,,,,139,Borreliella burgdorferi,,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin; heart; joint,enoyl CoA dehydratase/isomerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33195322,PubMed,10.3389/fmed.2020.573648,Front Med (Lausanne). 2020 Oct 26;7:573648,lyl@wmu.edu.cn,Strains overexpressing hk2 had reduced infectivity in mice.,Q Liu 2020,2020,1 gene,Liu-2020-Role of HK2 in the Enzootic Cycle of,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17305,PHI:10876,UniProt,O05858,GenBank,CCP46023,,,H37Rv,fasR,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,probable transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33193236,PubMed,10.3389/fmicb.2020.586285,Front Microbiol. 2020 Oct 27;11:586285,gago@ibr-conicet.gov.ar,FasR was required for M. tuberculosis replication in macrophages.,S Mondino 2020,2020,1 gene,Mondino-2020-FasR Regulates Fatty Acid Biosynt,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17306,PHI:10876,UniProt,O05858,GenBank,CCP46023,,,H37Rv,fasR,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,probable transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33193236,PubMed,10.3389/fmicb.2020.586285,Front Microbiol. 2020 Oct 27;11:586285,gago@ibr-conicet.gov.ar,"The fasR mutant resided in acidified cellular compartments, suggesting that the lipid perturbation caused by the mutation prevented M. tuberculosis inhibition of phagolysosome maturation.",S Mondino 2020,2020,1 gene,Mondino-2020-FasR Regulates Fatty Acid Biosynt,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17307,PHI:10877,UniProt,P9WL81,GenBank,CCP45373,,,H37Rv,Rv2577,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC 1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,alkaline phosphatase/phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33193164,PubMed,10.3389/fmicb.2020.570794,Front Microbiol. 2020 Oct 22;11:570794,mforrellad@gmail.com,A mutation introduced in Rv2577 reduced the replication of Mtb in mouse organs and impaired the arrest of phagosomes containing mycobacteria in early endosomes.,M A Forrellad 2020,2020,1 gene,Forrellad-2020-Rv2577 of Mycobacterium tubercu,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17308,PHI:10877,UniProt,P9WL81,GenBank,CCP45373,,,H37Rv,Rv2577,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC 1551,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,alkaline phosphatase/phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33193164,PubMed,10.3389/fmicb.2020.570794,Front Microbiol. 2020 Oct 22;11:570794,mforrellad@gmail.com,A mutation introduced in Rv2577 reduced the replication of Mtb in mouse organs and impaired the arrest of phagosomes containing mycobacteria in early endosomes.,M A Forrellad 2020,2020,1 gene,Forrellad-2020-Rv2577 of Mycobacterium tubercu,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17309,PHI:10878,UniProt,A0A0J9V3Z8,GenBank,KNB05581,,,4287,cna1 (XP_018243626),chromosome 4,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Farmer 301,,,root,serine/threonine-protein phosphatase 2B catalytic subunit,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33193126,PubMed,10.3389/fmicb.2020.539702,Front Microbiol. 2020 Oct 22;11:539702,ychen28@ntu.edu.tw,"Both cna1 and cnb1 mutants showed defects in calcineurin phosphatase activity, vegetative growth and conidiation as compared to the wild type.",Y H Hou 2020,2020,2 genes,"Hou-2020-Calcineurin Regulates Conidiation, Ch",BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17310,PHI:10879,UniProt,A0A0D2XC66,GenBank,KNA96197,,,4287,cnb1 (XP_018234243),chromosome 5,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Farmer 301,,,root,calcineurin subunit B,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33193126,PubMed,10.3389/fmicb.2020.539702,Front Microbiol. 2020 Oct 22;11:539702,ychen28@ntu.edu.tw,"Both cna1 and cnb1 mutants showed defects in calcineurin phosphatase activity, vegetative growth and conidiation as compared to the wild type.",Y H Hou 2020,2020,2 genes,"Hou-2020-Calcineurin Regulates Conidiation, Ch",BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17311,PHI:10880,UniProt,B8NYT3,GenBank,XP_002385498,,,NRRL3357,msb2 (AFLA_114450),,,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),cv. NC94022,,,seed,mucin family signaling protein,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl; Congo red (CR); SDS; caspofungin,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,33159717,PubMed,10.1111/1751-7915.13701,Microb Biotechnol. 2020 Nov 7,wshyyl@sina.com,"The deletion of msb2 gene caused defects in vegetative growth, sporulation and sclerotia formation.",L Qin 2020,2020,1 gene,Qin-2020-The membrane mucin Msb2 regulates afl,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17312,PHI:10880,UniProt,B8NYT3,GenBank,XP_002385498,,,NRRL3357,msb2 (AFLA_114450),,,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),eudicots,21020,Castanea sativa (related: chestnut),,,,,mucin family signaling protein,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl; Congo red (CR); SDS; caspofungin,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,33159717,PubMed,10.1111/1751-7915.13701,Microb Biotechnol. 2020 Nov 7,wshyyl@sina.com,"The deletion of msb2 gene caused defects in vegetative growth, sporulation and sclerotia formation.",L Qin 2020,2020,1 gene,Qin-2020-The membrane mucin Msb2 regulates afl,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17313,PHI:10881,UniProt,J9VJ28,GenBank,AFR92604,,,H99,olp1 (CNAG_00472),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,oxidoreductase-like protein,,,,reduced virulence,,,,,,,,reduced,,no,5-FC; LiCl,5-fluorocytosine CAS no.: CAS:2022-85-7; LiCl: CHEBI:48607,,,,,gene deletion: full; gene complementation,,,YVS,33158259,PubMed,10.3390/microorganisms8111730,Microorganisms. 2020 Nov 4;8(11):1730,wyj0213@email.swu.edu.cn,Olp1D mutants showed significant defects in hyphae growth and basidiospores production during bisexual reproduction.,Q K Yu 2020,2020,1 gene,Yu-2020-The Role of Oxidoreductase-Like Protei,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17314,PHI:10882,UniProt,Q6FMU4,GenBank,CAG61411,,,CBS 138,ath1 (CAGL0K05137g),chromosome K,,,,,,5478,Candida glabrata,284593,CBS 138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; kidney,secreted acid trehalase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33146242,PubMed,10.1590/0074-02760200401,Mem Inst Oswaldo Cruz. 2020 Oct 30;115:e200401,boris.stambuk@ufsc.br,Significantly lower virulence of the ath1Δ strain was observed in a murine model of infection with either normal or immunocompromised mice.,R G Lopes 2020,2020,1 gene,Lopes-2020-The secreted acid trehalase encoded,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17315,PHI:10883,UniProt,Q6FTS5,GenBank,CAG59293,,,CBS 138,Tog1 (CAGL0F09229g),chromosome F,,,,,,5478,Candida glabrata,,KUE100,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemocyte,transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33135521,PubMed,10.1080/21505594.2020.1839231,Virulence. 2020 Dec;11(1):1522-1538,mnpct@tecnico.ulisboa.pt,"CgTog1 was a specific regulator of virulence in C. glabrata, contributing to oxidative stress resistance and survival upon phagocytosis by host immune cells.",P Pais 2020,2020,1 gene,Pais-2020-A new regulator in the crossroads of,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17316,PHI:10884,UniProt,I6YB49,GenBank,CCP45900,,,H37Rv,Rv3091,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen; kidney; peritoneal macrophage,conserved protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,heterologous expression; altered gene expression / gene regulation: overexpression,,,YVS,33042041,PubMed,10.3389/fmicb.2020.532371,Front Microbiol. 2020 Sep 11;11:2204. doi: 10.3389/fmicb.2020.532371. eCollection 2020.,liusiguo@caas.cn,The presence of Rv3091 enhanced the intracellular survival capability of M. smegmatis in murine peritoneal macrophages.,Z Cui 2020,2020,1 gene,"Cui-2020-Rv3091, An Extracellular Patatin-Like",BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17317,PHI:10885,UniProt,J5JS08,GenBank,EJP67713,,,ARSEF 2860,BbCwp (BBA_03493),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemocyte,cell wall protein,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; sorbitol; menadione,NaCl: CHEBI:26710; sorbitol: CHEBI:17924; menadione: CHEBI:28869,,,,,gene mutation; gene complementation,,,YVS,33017218,PubMed,10.1080/21505594.2020.1827886,Virulence. 2020; 11(1): 1352–1365.,nc.ude.ujz@hsgniy,ΔBbCwp mutant displayed a significantly enhanced sensitivity to osmotic and oxidative stresses.,J L Ding 2020,2020,1 gene,Ding-2020-Transcriptomic analyses reveal compr,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17318,PHI:10886,,no data found,,,,,,ersA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,lung infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCrl,,,lung; bronchoalveolar lavage fluid,small RNA,,,,reduced virulence,,,,,,,,,,no,amikacin; gentamicin; ceftazidime; imipenem; meropenem; ciprofloxacin; cefepime,amikacin: CHEBI:2637; gentamicin: CHEBI:17833; ceftazidime: CHEBI:3508; imipenem: CHEBI:471744; meropenem: CHEBI:43968; ciprofloxacin: CHEBI:100241; cefepime: CHEBI:478164,,,,,gene deletion: full,,,YVS,33055260,PubMed,10.1128/mSphere.00909-20,mSphere. 2020 Oct 14;5(5):e00909-20.doi: 10.1128/mSphere.00909-20.,giovanni.bertoni@unimi.it.,The deletion of ErsA impaired virulence and decreases the proinflammatory response in a murine model of airway infection.,S Ferrara 2020,2020,1 gene,Ferrara-2020-The Small RNA ErsA Plays a Role i,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17319,PHI:10887,,no data found,,,,,,PXO_RS20535,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,eudicots,4530,Oryza sativa (related: rice),subsp. japonica cv. Dongjin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,33212951,PubMed,10.3390/pathogens9110956,Pathogens. 2020 Nov 17;9(11):956,swlee6803@khu.ac.kr,"The mutant strain lost virulence, produced significantly less biofilm, and showed remarkably reduced motility in swimming, swarming, and twitching.",A Antar 2020,2020,1 gene,"Antar-2020-PXO_RS20535, Encoding a Novel Respo",BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17320,PHI:10888,UniProt,K9GJX7,GenBank,EKV21199,,,Pd1,efeA (PDIP_08660),,,,,,,36651,Penicillium digitatum,1170230,Pd1,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navel,,,fruit,2-oxoglutarate-dependent ethylene-forming enzyme,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32957714,PubMed,10.3390/jof6030175,J Fungi (Basel). 2020 Sep; 6(3): 175,lgonzalez@iata.csic.es,Ethylene production by P. digitatum was dispensable for orange fruit infection.,A R Ballester 2020,2020,1 gene,Ballester-2020-EFE-Mediated Ethylene Synthesis,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17321,PHI:10889,UniProt,A0A381CQL2,GenBank,EAJ7070563,,,CS99046,CzcD,YP14_07665,,,,,,197,Campylobacter jejuni,192222,NCTC 11168,campylobacteriosis; gastroenteritis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cation transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33064782,PubMed,10.1371/journal.ppat.1009008,PLoS Pathog. 2020 Oct; 16(10): e1009008,james.d.linton@manchester.ac.uk,CzcD inactivation attenuated larval killing in a Galleria infection model and that at 32°C disrupting RNAT secondary structure to allow CzcD production can enhance killing.,H BarnawiI 2020,2020,1 gene,Barnawi-2020-RNA-based thermoregulation of a C,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17322,PHI:10890,UniProt,S7WCF1,GenBank,EPR64534,,,GT1,spy (TGGT1_273500),,,,,,,5811,Toxoplasma gondii,,CZ1,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,abdomen; brain,O-fucosyltransferase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33158988,PubMed,10.1074/jbc.RA120.015883,J Biol Chem. 2020 Nov 6:jbc.RA120.015883,giulia.bandini@york.ac.uk,The Δspy tachyzoites of a luciferase-expressing type II strain exhibited infection kinetics in mice similar to wild type but increased persistence in the chronic brain phase,G Bandini 2020,2020,1 gene,Bandini-2020-The nucleocytosolic O-fucosyltran,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17323,PHI:10891,UniProt,G2WSS3,GenBank,EGY17172,,,VdLs.17,frq,chromosome 1,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia,,,leaf,frequency clock protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,33013740,PubMed,10.3389/fmicb.2020.01977,Front Microbiol. 2020; 11: 1977,richard.harrison@niab.ac.uk,VdΔfrq mutants displayed growth defects and reduced pathogenicity in a strain dependent manner.,E Cascant-Lopez 2020,2020,1 gene,Cascant-Lopez-2020-No Evidence That Homologs o,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17324,PHI:10891,UniProt,G2WSS3,GenBank,EGY17172,,,VdLs.17,frq,chromosome 1,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3747,Fragaria x ananassa (related: strawberry),cv. Hapil,,,leaf,frequency clock protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,33013740,PubMed,10.3389/fmicb.2020.01977,Front Microbiol. 2020; 11: 1977,richard.harrison@niab.ac.uk,VdΔfrq mutants displayed growth defects and reduced pathogenicity in a strain dependent manner.,E Cascant-Lopez 2020,2020,1 gene,Cascant-Lopez-2020-No Evidence That Homologs o,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17325,PHI:10892,UniProt,J9VVE4,GenBank,AFR98238,,,H99,Cmp1 (CNAG_06000),chromosome 12,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,mannoprotein,,,,reduced virulence,,,,,,,,,,no,Congo red; SDS; sorbitol; NaCl; H2O2; NaNO2,Congo red: CHEBI:34653; SDS: CHEBI:8984; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; NaNO2: CHEBI:78870,,,,,gene deletion: full; gene complementation,,,YVS,33114434,PubMed,10.3390/pathogens9110881,Pathogens.2020 Oct 24;9(11):881,tongbaoliu@swu.edu.cn,Cmp1D mutant or the CMP1 overexpression strain was significantly attenuated in a murine inhalation model of cryptococcosis.,L T Han 2020,2020,1 gene,Han-2020-A Predicted Mannoprotein Cmp1 Regulat,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17326,PHI:10892,UniProt,J9VVE4,GenBank,AFR98238,,,H99,Cmp1 (CNAG_06000),chromosome 12,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,mannoprotein,,,,reduced virulence,,,,,,,,,,no,Congo red; SDS; sorbitol; NaCl; H2O2; NaNO2,Congo red: CHEBI:34653; SDS: CHEBI:8984; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; NaNO2: CHEBI:78870,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33114434,PubMed,10.3390/pathogens9110881,Pathogens.2020 Oct 24;9(11):881,tongbaoliu@swu.edu.cn,Cmp1D mutant or the CMP1 overexpression strain was significantly attenuated in a murine inhalation model of cryptococcosis.,L T Han 2020,2020,1 gene,Han-2020-A Predicted Mannoprotein Cmp1 Regulat,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17327,PHI:10892,UniProt,J9VVE4,GenBank,AFR98238,,,H99,Cmp1 (CNAG_06000),chromosome 12,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mannoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,Congo red; SDS; sorbitol; NaCl; H2O2; NaNO2,Congo red: CHEBI:34653; SDS: CHEBI:8984; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; H2O2: CHEBI:16240; NaNO2: CHEBI:78870,,,,,gene deletion: full; gene complementation,,,YVS,33114434,PubMed,10.3390/pathogens9110881,Pathogens.2020 Oct 24;9(11):881,tongbaoliu@swu.edu.cn,Cmp1D mutant or the CMP1 overexpression strain was significantly attenuated in a murine inhalation model of cryptococcosis.,L T Han 2020,2020,1 gene,Han-2020-A Predicted Mannoprotein Cmp1 Regulat,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17328,PHI:10893,UniProt,Q4WYQ9,GenBank,EAL92194,,,Af293,RgdA (Afu3g13920),chromosome 3,,,,,,746128,Aspergillus fumigatus,330879,Af293,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CrlOri:CD-1(ICR),,,lung,APSES transcription factor,,,gliotoxin biosynthesis,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33177217,PubMed,10.1128/mSphere.00998-20,mSphere.2020 Nov 11;5(6):e00998-20,shinks@dju.kr,"While the ΔrgdA mutant exhibited elevated production of GT, ΔrgdA strains showed reduced virulence in the mouse model.",S C Jun 2020,2020,1 gene,Jun-2020-The Putative APSES Transcription Fact,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17329,PHI:10894,UniProt,Q4WJG4,GenBank,EAL88318,,,Af293,Afmed15 (AFUA_1G06060),chromosome 1,,,,,,746128,Aspergillus fumigatus,,A1161,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,conserved hypothetical protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33028685,PubMed,10.1128/mSphere.00771-20,mSphere.2020 Oct 7;5(5):e00771-20,szzhang@njnu.edu.cn,The overexpression of Afmed15 caused fungal death accompanied by intensive autophagy.,L Guan 2020,2020,1 gene,Guan-2020-Precise Expression of Afmed15 Is Cru,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17330,PHI:10894,UniProt,Q4WJG4,GenBank,EAL88318,,,Af293,Afmed15 (AFUA_1G06060),chromosome 1,,,,,,746128,Aspergillus fumigatus,,A1161,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,conserved hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33028685,PubMed,10.1128/mSphere.00771-20,mSphere.2020 Oct 7;5(5):e00771-20,szzhang@njnu.edu.cn,The overexpression of Afmed15 caused fungal death accompanied by intensive autophagy.,L Guan 2020,2020,1 gene,Guan-2020-Precise Expression of Afmed15 Is Cru,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17331,PHI:10895,UniProt,C1G842,GenBank,EEH47249,,,Pb18,PCN (PADG_03347),,,,,,,121759,Paracoccidioides brasiliensis,,,paracoccidioidomycosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; bone marrow-derived macrophage,paracoccin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33201217,PubMed,10.1093/infdis/jiaa707,J Infect Dis.2020 Nov 17;jiaa707,frodrigues@med.uminho.pt,"PCN expression was critical for P. brasiliensis pulmonary proliferation and host damage, highlighting PCN as a key virulence factor.",R A Goncales 2020,2020,1 gene,Gonçales-2020-Paracoccin overexpression in Par,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17332,PHI:10895,UniProt,C1G842,GenBank,EEH47249,,,Pb18,PCN (PADG_03347),,,,,,,121759,Paracoccidioides brasiliensis,,,paracoccidioidomycosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,paracoccin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33201217,PubMed,10.1093/infdis/jiaa707,J Infect Dis.2020 Nov 17;jiaa707,frodrigues@med.uminho.pt,"PCN expression was critical for P. brasiliensis pulmonary proliferation and host damage, highlighting PCN as a key virulence factor.",R A Goncales 2020,2020,1 gene,Gonçales-2020-Paracoccin overexpression in Par,BATCH_103A,2020-11-01,MC,,,,,,,,,,,,,
,,Record 17333,PHI:10896,UniProt,A0A1P8DAB0,GenBank,APU53507,,,Cg-14,crzA,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,seed plants,28977,Cunninghamia lanceolata (related: china fir),,,,leaf,calcineurin-responsive C2H2 transcription factor,,,,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,Congo red; calcofluor white; sodium dodecylsulfate; CaCl2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,33082723,PubMed,10.5423/PPJ.OA.04.2020.0071,Plant Pathol J. 2020 Oct 1;36(5):385-397,lhuang@njfu.edu.cn,Deletion of the CgCRZA inhibited the development of invasive structures and lost pathogenicity to plant hosts.,P Wang 2020,2020,1 gene,Wang-2020-Calcineurin-Responsive Transcription,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17334,PHI:10896,UniProt,A0A1P8DAB0,GenBank,APU53507,,,Cg-14,crzA,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,eudicots,3690,Populus x canadensis (related: carolina poplar),cv. Nanlin 895,,,leaf,calcineurin-responsive C2H2 transcription factor,,,,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,Congo red; calcofluor white; sodium dodecylsulfate; CaCl2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,33082723,PubMed,10.5423/PPJ.OA.04.2020.0071,Plant Pathol J. 2020 Oct 1;36(5):385-397,lhuang@njfu.edu.cn,Deletion of the CgCRZA inhibited the development of invasive structures and lost pathogenicity to plant hosts.,P Wang 2020,2020,1 gene,Wang-2020-Calcineurin-Responsive Transcription,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17335,PHI:10896,UniProt,A0A1P8DAB0,GenBank,APU53507,,,Cg-14,crzA,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,flowering plants,215539,Liriodendron chinense x Liriodendron tulipifera (no common name found),,,,leaf,calcineurin-responsive C2H2 transcription factor,,,,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,Congo red; calcofluor white; sodium dodecylsulfate; CaCl2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,33082723,PubMed,10.5423/PPJ.OA.04.2020.0071,Plant Pathol J. 2020 Oct 1;36(5):385-397,lhuang@njfu.edu.cn,Deletion of the CgCRZA inhibited the development of invasive structures and lost pathogenicity to plant hosts.,P Wang 2020,2020,1 gene,Wang-2020-Calcineurin-Responsive Transcription,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17336,PHI:10896,UniProt,A0A1P8DAB0,GenBank,APU53507,,,Cg-14,crzA,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,seed plants,28977,Cunninghamia lanceolata (related: china fir),,,,leaf,calcineurin-responsive C2H2 transcription factor,,,,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,Congo red; calcofluor white; sodium dodecylsulfate; CaCl2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,33082723,PubMed,10.5423/PPJ.OA.04.2020.0071,Plant Pathol J. 2020 Oct 1;36(5):385-397,lhuang@njfu.edu.cn,Deletion of the CgCRZA inhibited the development of invasive structures and lost pathogenicity to plant hosts.,P Wang 2020,2020,1 gene,Wang-2020-Calcineurin-Responsive Transcription,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17337,PHI:10896,UniProt,A0A1P8DAB0,GenBank,APU53507,,,Cg-14,crzA,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,eudicots,3690,Populus x canadensis (related: carolina poplar),cv. Nanlin 895,,,leaf,calcineurin-responsive C2H2 transcription factor,,,,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,Congo red; calcofluor white; sodium dodecylsulfate; CaCl2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,33082723,PubMed,10.5423/PPJ.OA.04.2020.0071,Plant Pathol J. 2020 Oct 1;36(5):385-397,lhuang@njfu.edu.cn,Deletion of the CgCRZA inhibited the development of invasive structures and lost pathogenicity to plant hosts.,P Wang 2020,2020,1 gene,Wang-2020-Calcineurin-Responsive Transcription,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17338,PHI:10896,UniProt,A0A1P8DAB0,GenBank,APU53507,,,Cg-14,crzA,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,flowering plants,215539,Liriodendron chinense x Liriodendron tulipifera (no common name found),,,,leaf,calcineurin-responsive C2H2 transcription factor,,,,reduced virulence,,yes,,,,reduced,,reduced,reduced,no,Congo red; calcofluor white; sodium dodecylsulfate; CaCl2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; SDS: CHEBI:8984; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,33082723,PubMed,10.5423/PPJ.OA.04.2020.0071,Plant Pathol J. 2020 Oct 1;36(5):385-397,lhuang@njfu.edu.cn,Deletion of the CgCRZA inhibited the development of invasive structures and lost pathogenicity to plant hosts.,P Wang 2020,2020,1 gene,Wang-2020-Calcineurin-Responsive Transcription,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17339,PHI:10897,,no data found,GenBank,OWY50363,,,Z7,pex6,,,,,,,5599,Alternaria alternata,,,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,heat shock protein,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,reduced,no,oleic acid; tween 20; calcofluor white; Congo red; methanol; FeCl3; EDTA; SDS,"oleic acid: CHEBI:16196, 20; tween: CHEBI:53424; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; methanol: CHEBI:17790; FeCl3: CHEBI:30808; EDTA: CHEBI:64758; SDS: CHEBI:8984",,,,,gene deletion: full; gene complementation,,,YVS,33114679,PubMed,10.3390/jof6040248,J Fungi (Basel). 2020 Oct 26;6(4):E248,krchung@nchu.edu.tw,The pex6 deficient mutant reduced toxin production by 40% compared to wild type and barely induce necrotic lesions on citrus leaves.,P C Wu 2020,2020,1 gene,Wu-2020-Proper Functions of Peroxisomes Are Vi,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17340,PHI:10898,UniProt,S7W1K5,GenBank,EPR58938,,,GT1,GRA45 (TGGT1_315620),,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,V-type proton ATPase subunit C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17341,PHI:10899,UniProt,S7W531,GenBank,EPR60028,,,GT1,GRA22 (TGGT1_215220),,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17342,PHI:10900,UniProt,S7V464,GenBank,EPR64716,,,GT1,TGGT1_269950,,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,thioredoxin domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17343,PHI:10901,UniProt,A0A125YKK5,GenBank,EPR62504,,,GT1,TGGT1_263560,,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17344,PHI:10898,UniProt,S7W1K5,GenBank,EPR58938,,,GT1,GRA45 (TGGT1_315620),,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10117,Rattus rattus (related: black rat),,,,bone marrow-derived macrophage,V-type proton ATPase subunit C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17345,PHI:10899,UniProt,S7W531,GenBank,EPR60028,,,GT1,GRA22 (TGGT1_215220),,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10117,Rattus rattus (related: black rat),,,,bone marrow-derived macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17346,PHI:10900,UniProt,S7V464,GenBank,EPR64716,,,GT1,TGGT1_269950,,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10117,Rattus rattus (related: black rat),,,,bone marrow-derived macrophage,thioredoxin domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17347,PHI:10901,UniProt,A0A125YKK5,GenBank,EPR62504,,,GT1,TGGT1_263560,,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10117,Rattus rattus (related: black rat),,,,bone marrow-derived macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17348,PHI:10898,UniProt,S7W1K5,GenBank,EPR58938,,,GT1,GRA45 (TGGT1_315620),,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,V-type proton ATPase subunit C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17349,PHI:10899,UniProt,S7W531,GenBank,EPR60028,,,GT1,GRA22 (TGGT1_215220),,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17350,PHI:10900,UniProt,S7V464,GenBank,EPR64716,,,GT1,TGGT1_269950,,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,thioredoxin domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17351,PHI:10901,UniProt,A0A125YKK5,GenBank,EPR62504,,,GT1,TGGT1_263560,,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17352,PHI:10898,UniProt,S7W1K5,GenBank,EPR58938,,,GT1,GRA45 (TGGT1_315620),,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,peritoneal macrophage,V-type proton ATPase subunit C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17353,PHI:10900,UniProt,S7V464,GenBank,EPR64716,,,GT1,TGGT1_269950,,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,peritoneal macrophage,thioredoxin domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33067458,PubMed,10.1038/s41467-020-18991-8,Nat Commun. 2020 Oct 16;11(1):5258,jsaeij@ucdavis.edu,Parasites lacking GRA45 were more susceptible to IFNgamma-mediated growth inhibition and have reduced virulence in mice.,Y Wang 2020,2020,4 genes,Wang-2020-Genome-wide screens identify Toxopla,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17354,PHI:10902,UniProt,S6TYC4,GenBank,EPN46999,,,ICMP 18807,hopR1,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32969167,PubMed,10.1111/mpp.12989,Mol Plant Pathol. 2020 Nov;21(11):1467-1480,jay.jayaraman@plantandfood.co.nz,The conserved effector locus (CEL) was required for full virulence of Psa3 on Hort16A kiwifruit plants.,J Jayaraman 2020,2020,3 genes,Jayaraman-2020-AvrE1 and HopR1 from Pseudomona,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17355,PHI:10903,UniProt,S6SR81,GenBank,EPN33784,,,ICMP 18807,hopM1,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32969167,PubMed,10.1111/mpp.12989,Mol Plant Pathol. 2020 Nov;21(11):1467-1480,jay.jayaraman@plantandfood.co.nz,The conserved effector locus (CEL) was required for full virulence of Psa3 on Hort16A kiwifruit plants.,J Jayaraman 2020,2020,3 genes,Jayaraman-2020-AvrE1 and HopR1 from Pseudomona,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17356,PHI:10904,UniProt,S6TWG5,GenBank,EPN33786,,,ICMP 18807,avrE1,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32969167,PubMed,10.1111/mpp.12989,Mol Plant Pathol. 2020 Nov;21(11):1467-1480,jay.jayaraman@plantandfood.co.nz,The conserved effector locus (CEL) was required for full virulence of Psa3 on Hort16A kiwifruit plants.,J Jayaraman 2020,2020,3 genes,Jayaraman-2020-AvrE1 and HopR1 from Pseudomona,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17357,PHI:10905,UniProt,D2TPE2,GenBank,CBG87511,,,ICC168,tolB,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,colon,colicin import protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32968151,PubMed,10.1038/s41598-020-72412-w,Sci Rep. 2020 Sep 23;10(1):15173,hirakawa@gunma-u.ac.jp,"The Citrobacter rodentium, tolB mutant, did not cause lethality in mice while it induced anti-bacterial immunity.",H Hirakawa 2020,2020,1 gene,Hirakawa-2020-Roles of the Tol-Pal system in t,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17358,PHI:10905,UniProt,D2TPE2,GenBank,CBG87511,,,ICC168,tolB,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,colicin import protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32968151,PubMed,10.1038/s41598-020-72412-w,Sci Rep. 2020 Sep 23;10(1):15173,hirakawa@gunma-u.ac.jp,"The Citrobacter rodentium, tolB mutant, did not cause lethality in mice while it induced anti-bacterial immunity.",H Hirakawa 2020,2020,1 gene,Hirakawa-2020-Roles of the Tol-Pal system in t,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17359,PHI:10906,UniProt,A0A3V4TDR2,GenBank,EAA7959359,,,FDA626170-11,clpP,,,,,,PHI:10907,28901,Salmonella enterica,550537,subsp. enterica serovar Enteritidis strain P125109,gastroenteritis,birds,9031,Gallus gallus (related: chicken),Hy-line brown,,,liver; spleen; cecum,ATP-dependent Clp protease proteolytic subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33150477,PubMed,10.1007/s42770-020-00399-7,Braz J Microbiol. 2020 Nov 4,oliveirocaetano@yahoo.com,SE ΔclpPfliD elicited more intense immune responses in the gut during early stages of infection than the wild type did.,F de Oliveira Barbosa 2020,2020,2 genes,de Oliveira Bar-2020-Immunological and bacteri,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17360,PHI:10907,UniProt,A0A3V4T872,GenBank,EAA7957375,,,FDA626170-11,fliD,,,,,,PHI:10906,28901,Salmonella enterica,550537,subsp. enterica serovar Enteritidis strain P125109,gastroenteritis,birds,9031,Gallus gallus (related: chicken),Hy-line brown,,,liver; spleen; cecum,flagellar hook-associated protein 2,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33150477,PubMed,10.1007/s42770-020-00399-7,Braz J Microbiol. 2020 Nov 4,oliveirocaetano@yahoo.com,SE ΔclpPfliD elicited more intense immune responses in the gut during early stages of infection than the wild type did.,F de Oliveira Barbosa 2020,2020,2 genes,de Oliveira Bar-2020-Immunological and bacteri,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17361,PHI:10908,UniProt,B8N096,GenBank,XP_002373650,,,NRRL3357,ssu72,,,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::pyrG),ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,putative phosphatase,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33202955,PubMed,10.3390/toxins12110717,Toxins (Basel). 2020 Nov 13;12(11):717,yjmail2008@fafu.edu.cn,"Deletion of ssu72 resulted in severe defects in vegetative growth, conidiation and sclerotia formation.",G Yang 2020,2020,1 gene,Yang-2020-Ssu72 Regulates Fungal Development,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17362,PHI:10908,UniProt,B8N096,GenBank,XP_002373650,,,NRRL3357,ssu72,,,,,,,5059,Aspergillus flavus,,CA14 PTS (Δku70 ΔpyrG::pyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,putative phosphatase,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33202955,PubMed,10.3390/toxins12110717,Toxins (Basel). 2020 Nov 13;12(11):717,yjmail2008@fafu.edu.cn,"Deletion of ssu72 resulted in severe defects in vegetative growth, conidiation and sclerotia formation.",G Yang 2020,2020,1 gene,Yang-2020-Ssu72 Regulates Fungal Development,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17363,PHI:10909,UniProt,Q4WGK0,GenBank,EAL86941,,,Af293,gprM (Afu7g05300),chromosome 7,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,G-protein coupled receptor,,,,reduced virulence,,,,,,,,wild type,,no,Congo red; calcofluor white; CaCl2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,33051372,PubMed,10.1128/mBio.02458-20,mBio. 2020 Oct 13;11(5):e02458-20,ggoldman@usp.br,The ΔgprM and ΔgprJ mutants are reduced in virulence in the Galleria mellonella insect model of invasive aspergillosis.,A P D C Filho 2020,2020,2 genes,Filho-2020-Aspergillus fumigatus G-Protein Cou,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17364,PHI:10910,UniProt,Q4WJ87,GenBank,EAL88395,,,Af293,gprJ (Afu1g06840),chromosome 1,,,,,,746128,Aspergillus fumigatus,,akuBKU80,invasive aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,G-protein coupled receptor,,,,reduced virulence,,,,,,,,wild type,,no,Congo red; calcofluor white; CaCl2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,33051372,PubMed,10.1128/mBio.02458-20,mBio. 2020 Oct 13;11(5):e02458-20,ggoldman@usp.br,The ΔgprM and ΔgprJ mutants are reduced in virulence in the Galleria mellonella insect model of invasive aspergillosis.,A P D C Filho 2020,2020,2 genes,Filho-2020-Aspergillus fumigatus G-Protein Cou,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17365,PHI:10909,UniProt,Q4WGK0,GenBank,EAL86941,,,Af293,gprM (Afu7g05300),chromosome 7,,,,,PHI:10910,746128,Aspergillus fumigatus,,akuBKU80,invasive aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,G-protein coupled receptor,,,,reduced virulence,,,,,,,,wild type,,no,Congo red; calcofluor white; CaCl2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,33051372,PubMed,10.1128/mBio.02458-20,mBio. 2020 Oct 13;11(5):e02458-20,ggoldman@usp.br,The ΔgprM and ΔgprJ mutants are reduced in virulence in the Galleria mellonella insect model of invasive aspergillosis.,A P D C Filho 2020,2020,2 genes,Filho-2020-Aspergillus fumigatus G-Protein Cou,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17366,PHI:10910,UniProt,Q4WJ87,GenBank,EAL88395,,,Af293,gprJ (Afu1g06840),chromosome 1,,,,,PHI:10909,746128,Aspergillus fumigatus,,akuBKU80,invasive aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,G-protein coupled receptor,,,,reduced virulence,,,,,,,,wild type,,no,Congo red; calcofluor white; CaCl2,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,YVS,33051372,PubMed,10.1128/mBio.02458-20,mBio. 2020 Oct 13;11(5):e02458-20,ggoldman@usp.br,The ΔgprM and ΔgprJ mutants are reduced in virulence in the Galleria mellonella insect model of invasive aspergillosis.,A P D C Filho 2020,2020,2 genes,Filho-2020-Aspergillus fumigatus G-Protein Cou,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17367,PHI:10911,UniProt,A0A0H3NIW0,GenBank,CBW18209,,,SL1344,ssek2,,,,,,PHI:10912,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Hela229 SEAP cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32974215,PubMed,10.3389/fcimb.2020.00419,Front Cell Infect Microbiol. 2020 Aug 19;10:419,cristina.giogha@hudson.org.au,"Compared to wild type SL1344, only the SPI-2 mutant showed significantly impaired replication in the HeLa229 SEAP cell line and RAW264.7 cells.",J Gan 2020,2020,2 genes,Gan-2020-The Salmonella Effector SseK3 Targets,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17368,PHI:10912,UniProt,A0A0H3NMP8,GenBank,CBW18025,,,SL1344,ssek3,,,,,,PHI:10911,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Hela229 SEAP cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32974215,PubMed,10.3389/fcimb.2020.00419,Front Cell Infect Microbiol. 2020 Aug 19;10:419,cristina.giogha@hudson.org.au,"Compared to wild type SL1344, only the SPI-2 mutant showed significantly impaired replication in the HeLa229 SEAP cell line and RAW264.7 cells.",J Gan 2020,2020,2 genes,Gan-2020-The Salmonella Effector SseK3 Targets,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17369,PHI:10911,UniProt,A0A0H3NIW0,GenBank,CBW18209,,,SL1344,ssek2,,,,,,PHI:10912,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32974215,PubMed,10.3389/fcimb.2020.00419,Front Cell Infect Microbiol. 2020 Aug 19;10:419,cristina.giogha@hudson.org.au,"Compared to wild type SL1344, only the SPI-2 mutant showed significantly impaired replication in the HeLa229 SEAP cell line and RAW264.7 cells.",J Gan 2020,2020,2 genes,Gan-2020-The Salmonella Effector SseK3 Targets,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17370,PHI:10912,UniProt,A0A0H3NMP8,GenBank,CBW18025,,,SL1344,ssek3,,,,,,PHI:10911,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32974215,PubMed,10.3389/fcimb.2020.00419,Front Cell Infect Microbiol. 2020 Aug 19;10:419,cristina.giogha@hudson.org.au,"Compared to wild type SL1344, only the SPI-2 mutant showed significantly impaired replication in the HeLa229 SEAP cell line and RAW264.7 cells.",J Gan 2020,2020,2 genes,Gan-2020-The Salmonella Effector SseK3 Targets,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17371,PHI:10913,UniProt,P45723,GenBank,AAA16442,,,Newman,PI-PLC,,,,,,,1280,Staphylococcus aureus,158878,JCM2874,septic shock,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,phosphatidylinositol-specific phospholipase C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33082376,PubMed,10.1038/s41598-020-74692-8,Sci Rep. 2020 Oct 20;10(1):17845,kfukami@toyaku.ac.jp,The loss of PI-PLC attenuated epidermal hyperplasia and the infiltration of Gr-1+ cells and CD4+ cells induced by S. aureus infection in the mouse model of AD.,Y Nakamura 2020,2020,1 gene,Nakamura-2020-Phosphatidylinositol-specific ph,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17372,PHI:10913,UniProt,P45723,GenBank,AAA16442,,,Newman,PI-PLC,,,,,,,1280,Staphylococcus aureus,158878,JCM2874,septic shock,primates,9606,Homo sapiens (related: human),HPEK cell line,,,keratinocyte,phosphatidylinositol-specific phospholipase C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33082376,PubMed,10.1038/s41598-020-74692-8,Sci Rep. 2020 Oct 20;10(1):17845,kfukami@toyaku.ac.jp,The loss of PI-PLC attenuated epidermal hyperplasia and the infiltration of Gr-1+ cells and CD4+ cells induced by S. aureus infection in the mouse model of AD.,Y Nakamura 2020,2020,1 gene,Nakamura-2020-Phosphatidylinositol-specific ph,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17373,PHI:10914,UniProt,Q8F3E8,GenBank,AAN49657,,,56601,LA2458,chromosome I,,,,,,173,Leptospira interrogans,,serovar Lai strain LR31,leptospirosis,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: synthetic peptide,,,YVS,33142957,PubMed,10.3390/pathogens9110906,Pathogens. 2020 Oct 30;9(11):906,piengchan.son@mahidol.edu,The synthetic peptide demonstrated dose-dependent cytotoxicity toward African green monkey kidney (Vero) cells via the apoptosis pathway.,S Paratsaphan 2020,2020,1 gene,Paratsaphan-2020-Characterization of a Novel P,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17374,PHI:10915,UniProt,N4UDW5,GenBank,ENH69552,,,race 1,ZtRlm1,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Obelisk,,,leaf,MADS-box transcription factor,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33013739,PubMed,10.3389/fmicb.2020.01976,Front Microbiol. 2020 Aug 18;11:1976,rahim.mehrabi@gmail.com,"Melanization, a phenomenon required for fruiting body formation, was significantly hampered in ZtRlm1 mutants.",N Mohammadi 2020,2020,1 gene,Mohammadi-2020-MADS-Box Transcription Factor Z,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17375,PHI:10916,,no data found,,,,,,Ssr54,,,,,,,623,Shigella flexneri,198214,serotype 2a strain 301,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,33042862,PubMed,10.3389/fcimb.2020.00483,Front Cell Infect Microbiol. 2020 Sep 16;10:483,mahui-28@163.com,"Virulence assessment, including guinea pig Sereny test and competitive invasion assays in mouse lungs, revealed that Ssr54 deletion significantly decreased S. flexneri virulence.",G Yang 2020,2020,1 gene,Yang-2020-A Novel sRNA in Shigella flexneri Th,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17376,PHI:10916,,no data found,,,,,,Ssr54,,,,,,,623,Shigella flexneri,198214,serotype 2a strain 301,shigellosis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,cornea,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,33042862,PubMed,10.3389/fcimb.2020.00483,Front Cell Infect Microbiol. 2020 Sep 16;10:483,mahui-28@163.com,"Virulence assessment, including guinea pig Sereny test and competitive invasion assays in mouse lungs, revealed that Ssr54 deletion significantly decreased S. flexneri virulence.",G Yang 2020,2020,1 gene,Yang-2020-A Novel sRNA in Shigella flexneri Th,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17377,PHI:10916,,no data found,,,,,,Ssr54,,,,,,,623,Shigella flexneri,198214,serotype 2a strain 301,shigellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,33042862,PubMed,10.3389/fcimb.2020.00483,Front Cell Infect Microbiol. 2020 Sep 16;10:483,mahui-28@163.com,"Virulence assessment, including guinea pig Sereny test and competitive invasion assays in mouse lungs, revealed that Ssr54 deletion significantly decreased S. flexneri virulence.",G Yang 2020,2020,1 gene,Yang-2020-A Novel sRNA in Shigella flexneri Th,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17378,PHI:10917,UniProt,Q8DQP4,GenBank,AAK99369,,,R6,bgaA,,,,,,,1313,Streptococcus pneumoniae,170187,serotype 4 strain TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,beta-galactosidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33072054,PubMed,10.3389/fmicb.2020.582437,Front Microbiol. 2020 Sep 24;11:582437,kawabata@dent.osaka-u.ac.jp,Deficiency of bgaA decreased pneumococcal virulence in a mouse model of sepsis.,M Yamaguchi 2020,2020,1 gene,Yamaguchi-2020-Role of BgaA as a Pneumococcal,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17379,PHI:10918,UniProt,O54081,GenBank,CAA73667,,,Newman,lukE,,LukE S-loop4,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,erythrocyte,pore forming toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33051210,PubMed,10.1074/jbc.RA120.015757,J Biol Chem. 2020 Oct 13:jbc.RA120.015757,victor.torres@nyulangone.org,Mutating the loop 4 of LukE abrogated cytotoxic activity globally.,M T Vasquez 2020,2020,1 gene,Vasquez-2020-Identification of a domain critic,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17380,PHI:10919,UniProt,D4I4J9,GenBank,CBA24187,,,CFPB1430,EaAdeP (EAMY 3685),,,,,,,552,Erwinia amylovora,,1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,putative AzgA family transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33152083,PubMed,10.1093/femsle/fnaa173,FEMS Microbiol Lett. 2020 Nov 5;367(20):fnaa173,mourad@pfw.edu,"Immature pear and apple fruit virulence assays revealed that an E. amylovora adeP::Camr mutant was still able to cause disease symptoms, however, with growth at a lower level, indicating that external adenine was utilized in disease establishment.",C R Alexander 2020,2020,1 gene,Alexander-2020-Functional characterization of,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17381,PHI:10919,UniProt,D4I4J9,GenBank,CBA24187,,,CFPB1430,EaAdeP (EAMY 3685),,,,,,,552,Erwinia amylovora,,1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Smoothie,,,fruit,putative AzgA family transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33152083,PubMed,10.1093/femsle/fnaa173,FEMS Microbiol Lett. 2020 Nov 5;367(20):fnaa173,mourad@pfw.edu,"Immature pear and apple fruit virulence assays revealed that an E. amylovora adeP::Camr mutant was still able to cause disease symptoms, however, with growth at a lower level, indicating that external adenine was utilized in disease establishment.",C R Alexander 2020,2020,1 gene,Alexander-2020-Functional characterization of,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17382,PHI:10920,UniProt,Q7MTF0,GenBank,AAQ66983,,,W83,cas3,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,CRISPR-associated helicase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32994292,PubMed,10.1128/mSystems.00852-20,mSystems. 2020 Sep 29;5(5):e00852-20,jfrias-lopez@dental.ufl.edu,The Δcas3 mutant resulted in a statistically significant increase in mortality of G. mellonella.,J Solbiati 2020,2020,1 gene,Solbiati-2020-Virulence of the Pathogen Porphy,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17383,PHI:10920,UniProt,Q7MTF0,GenBank,AAQ66983,,,W83,cas3,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,CRISPR-associated helicase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32994292,PubMed,10.1128/mSystems.00852-20,mSystems. 2020 Sep 29;5(5):e00852-20,jfrias-lopez@dental.ufl.edu,The Δcas3 mutant resulted in a statistically significant increase in mortality of G. mellonella.,J Solbiati 2020,2020,1 gene,Solbiati-2020-Virulence of the Pathogen Porphy,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17384,PHI:10921,UniProt,Q6MX50,GenBank,CCP43027,,,H37Rv,Rv0297,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,primates,9606,Homo sapiens (related: human),RAW 246.7,,,macrophage,PE-PGRS family protein,,,,unaffected pathogenicity,,,,,,,,,,no,CoCl2; H2O2,CoCl2: CHEBI:35696; H2O2: CHEBI:16240,,,,,other evidence: recombinant protein,,,YVS,33042856,PubMed,10.3389/fcimb.2020.00451,Front Cell Infect Microbiol. 2020 Sep 11;10:451,vc@jamiahamdard.ac.in,"Macrophages infected with rM.smeg expressing Rv0297 produced nitric oxide and underwent apoptosis, which aided in the dissemination of pathogen in the later stages aof infection.",T Sharma 2020,2020,1 gene,Sharma-2020-PGRS Domain of Rv0297 of Mycobacte,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17385,PHI:10921,UniProt,Q6MX50,GenBank,CCP43027,,,H37Rv,Rv0297,,recombinant M.smeg_Rv0297 expressing PGRS domain,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,primates,9606,Homo sapiens (related: human),RAW 246.7,,,macrophage,PE-PGRS family protein,,,,unaffected pathogenicity,,,,,,,,,,no,CoCl2; H2O2,CoCl2: CHEBI:35696; H2O2: CHEBI:16240,,,,,other evidence: recombinant protein,,,YVS,33042856,PubMed,10.3389/fcimb.2020.00451,Front Cell Infect Microbiol. 2020 Sep 11;10:451,vc@jamiahamdard.ac.in,"Macrophages infected with rM.smeg expressing Rv0297 produced nitric oxide and underwent apoptosis, which aided in the dissemination of pathogen in the later stages aof infection.",T Sharma 2020,2020,1 gene,Sharma-2020-PGRS Domain of Rv0297 of Mycobacte,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17386,PHI:10921,UniProt,Q6MX50,GenBank,CCP43027,,,H37Rv,Rv0297,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,PE-PGRS family protein,,,,unaffected pathogenicity,,,,,,,,,,no,CoCl2; H2O2,CoCl2: CHEBI:35696; H2O2: CHEBI:16240,,,,,other evidence: recombinant protein,,,YVS,33042856,PubMed,10.3389/fcimb.2020.00451,Front Cell Infect Microbiol. 2020 Sep 11;10:451,vc@jamiahamdard.ac.in,"Macrophages infected with rM.smeg expressing Rv0297 produced nitric oxide and underwent apoptosis, which aided in the dissemination of pathogen in the later stages aof infection.",T Sharma 2020,2020,1 gene,Sharma-2020-PGRS Domain of Rv0297 of Mycobacte,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17387,PHI:10921,UniProt,Q6MX50,GenBank,CCP43027,,,H37Rv,Rv0297,,recombinant M.smeg_Rv0297 expressing PGRS domain,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,PE-PGRS family protein,,,,unaffected pathogenicity,,,,,,,,,,no,CoCl2; H2O2,CoCl2: CHEBI:35696; H2O2: CHEBI:16240,,,,,other evidence: recombinant protein,,,YVS,33042856,PubMed,10.3389/fcimb.2020.00451,Front Cell Infect Microbiol. 2020 Sep 11;10:451,vc@jamiahamdard.ac.in,"Macrophages infected with rM.smeg expressing Rv0297 produced nitric oxide and underwent apoptosis, which aided in the dissemination of pathogen in the later stages aof infection.",T Sharma 2020,2020,1 gene,Sharma-2020-PGRS Domain of Rv0297 of Mycobacte,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17388,PHI:10922,UniProt,Q66T04,GenBank,AAU10474,,,KP6,ampR,,,,,,,573,Klebsiella pneumoniae,,KL47,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,regulator of the LysR family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33116662,PubMed,10.2147/IDR.S269275,Infect Drug Resist. 2020 Oct 6;13:3431-3441,whuang_sz@163.com,More capsule polysaccharide was produced by ampR+ and ampR complementary strains compared to ampR- strains.,M Zhang 2020,2020,1 gene,Zhang-2020-AmpR Increases the Virulence of Car,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17389,PHI:10922,UniProt,Q66T04,GenBank,AAU10474,,,KP6,ampR,,,,,,,573,Klebsiella pneumoniae,,KL1,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,regulator of the LysR family,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33116662,PubMed,10.2147/IDR.S269275,Infect Drug Resist. 2020 Oct 6;13:3431-3441,whuang_sz@163.com,More capsule polysaccharide was produced by ampR+ and ampR complementary strains compared to ampR- strains.,M Zhang 2020,2020,1 gene,Zhang-2020-AmpR Increases the Virulence of Car,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17390,PHI:10923,UniProt,K9G4Z7,GenBank,EKV15997,,,PHI26,PDIG_23520 (Sca),,,,,,,36651,Penicillium digitatum,1170229,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navel; cv. Lanelate,,,fruit,cysteine-rich anionic (Sca) protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,33023232,PubMed,10.3390/jof6040203,J Fungi (Basel). 2020 Oct 2;6(4):E203,mgandia@iata.csic.es,Sca improved P. digitatum virulence in vivo.,S Garrigues 2020,2020,1 gene,Garrigues-2020-A Novel Secreted Cysteine-Rich,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17391,PHI:10923,UniProt,K9G4Z7,GenBank,EKV15997,,,PHI26,PDIG_23520 (Sca),,,,,,,36651,Penicillium digitatum,1170229,PHI26,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navel; cv. Lanelate,,,fruit,cysteine-rich anionic (Sca) protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33023232,PubMed,10.3390/jof6040203,J Fungi (Basel). 2020 Oct 2;6(4):E203,mgandia@iata.csic.es,Sca improved P. digitatum virulence in vivo.,S Garrigues 2020,2020,1 gene,Garrigues-2020-A Novel Secreted Cysteine-Rich,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17392,PHI:10924,,no data found,,,,,,rr35 (PXO_RS20535),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,leaf,orphan response regulator,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,33212951,PubMed,10.3390/pathogens9110956,Pathogens. 2020 Nov 17;9(11):956,swlee6803@khu.ac.kr,"The mutant strain lost virulence, produced significantly less biofilm, and showed remarkably reduced motility in swimming, swarming, and twitching.",A Antar 2020,2020,1 gene,"Antar-2020-PXO_RS20535, Encoding a Novel Respo",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17393,PHI:10925,UniProt,G4N713,GenBank,EHA49926,,,70-15,MoSEC61beta (MGG_03644),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,seedling,"protein-conducting channel for transport, beta subunit",,,,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,SDS; Congo red; calcofluor white,SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33200669,PubMed,10.1080/21505594.2020.1848983,Virulence. 2020 Dec;11(1):1685-1700,fuchenglin@zju.edu.cn,"The ΔMosec61β mutant exhibited highly branched mycelial morphology, reduced conidiation, high sensitivity to cell wall integrity stress, severely reduced virulence to rice and barley, and restricted biotrophic invasion.",Y Y Wei 2020,2020,1 gene,"Wei-2020-MoSec61?, the beta subunit of Sec61",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17394,PHI:10925,UniProt,G4N713,GenBank,EHA49926,,,70-15,MoSEC61beta (MGG_03644),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,"protein-conducting channel for transport, beta subunit",,,,reduced virulence,,no,yes,yes,,reduced,,reduced,wild type,no,SDS; Congo red; calcofluor white,SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33200669,PubMed,10.1080/21505594.2020.1848983,Virulence. 2020 Dec;11(1):1685-1700,fuchenglin@zju.edu.cn,"The ΔMosec61β mutant exhibited highly branched mycelial morphology, reduced conidiation, high sensitivity to cell wall integrity stress, severely reduced virulence to rice and barley, and restricted biotrophic invasion.",Y Y Wei 2020,2020,1 gene,"Wei-2020-MoSec61?, the beta subunit of Sec61",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17395,PHI:10926,UniProt,J4UKA7,GenBank,EJP64582,,,ARSEF 2860,HapX (BBA_06576),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,basic leucine zipper (bZip) transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33051379,PubMed,10.1128/mSystems.00695-20,mSystems. 2020 Oct 13;5(5):e00695-20,yingsh@zju.edu.cn,"Exogenous oleic acid could partially or completely restore the impaired phenotypes of the BbHapX mutant, including germination rate, membrane integrity, vegetative growth, and virulence.",Y J Peng 2020,2020,1 gene,"Peng-2020-HapX, an Indispensable bZIP Transcri",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17396,PHI:10927,UniProt,I1RJK8,GenBank,CEF78952,,,PH-1,FgMsb3 (FGSG_04033),chromosome 2,,,FgSpa2 (FGSG_00932); FgRab8 (FGSG_06209),UniProt: I1RBK6; GenBank: CEF72976; UniProt: I1RQ70; GenBank: CEF86840,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhengmai,,,spikelet,Rab-GAP TBC domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978966,PubMed,10.1111/nph.16935,New Phytol. 2020 Sep 26,wenhuiz@fafu.edu.cn,All the polarisome components were required for the development and pathogenicity of F. graminearum.,H Zheng 2020,2020,4 genes,"Zheng-2020-FgSpa2 recruits FgMsb3, a Rab8 GAP",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17397,PHI:10928,UniProt,I1RBK6,GenBank,CEF72976,,,PH-1,FgSpa2 (FGSG_00932),chromosome 1,,,FgMsb3 (FGSG_04033); FgRab8 (FGSG_06209),UniProt: I1RJK8; GenBank: CEF78952; UniProt: I1RQ70; GenBank: CEF86840,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhengmai,,,spikelet,uncharacterized protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978966,PubMed,10.1111/nph.16935,New Phytol. 2020 Sep 26,wenhuiz@fafu.edu.cn,All the polarisome components were required for the development and pathogenicity of F. graminearum.,H Zheng 2020,2020,4 genes,"Zheng-2020-FgSpa2 recruits FgMsb3, a Rab8 GAP",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17398,PHI:10929,UniProt,I1RML6,GenBank,CEF88470,,,PH-1,FgPea2 (FGSG_05208),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhengmai,,,spikelet,Uds1 domain-containing protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978966,PubMed,10.1111/nph.16935,New Phytol. 2020 Sep 26,wenhuiz@fafu.edu.cn,All the polarisome components were required for the development and pathogenicity of F. graminearum.,H Zheng 2020,2020,4 genes,"Zheng-2020-FgSpa2 recruits FgMsb3, a Rab8 GAP",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17399,PHI:10930,UniProt,I1RKG4,GenBank,CEF79360,,,PH-1,FgBud6 (FGSG_04366),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhengmai,,,spikelet,AIP3 domain-containing protein,,,,reduced virulence,,,,,,,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978966,PubMed,10.1111/nph.16935,New Phytol. 2020 Sep 26,wenhuiz@fafu.edu.cn,All the polarisome components were required for the development and pathogenicity of F. graminearum.,H Zheng 2020,2020,4 genes,"Zheng-2020-FgSpa2 recruits FgMsb3, a Rab8 GAP",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17400,PHI:10931,UniProt,P18177,GenBank,CAA37298,,,VPI 10463,tcdB,,D270N substitution in the GT domain of TcdB,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,cecum,toxin B,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32960931,PubMed,10.1371/journal.ppat.1008852,PLoS Pathog. 2020 Sep 22;16(9):e1008852,roman.melnyk@sickkids.ca,TcdB glucosyltransferase activity was indispensable for disease pathogenesis.,T W Bilverstone 2020,2020,2 genes,Bilverstone-2020-The glucosyltransferase activ,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17401,PHI:10932,UniProt,P16154,GenBank,CAA36094,,,VPI 10463,tcdA,,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,cecum,toxin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32960931,PubMed,10.1371/journal.ppat.1008852,PLoS Pathog. 2020 Sep 22;16(9):e1008852,roman.melnyk@sickkids.ca,TcdB glucosyltransferase activity was indispensable for disease pathogenesis.,T W Bilverstone 2020,2020,2 genes,Bilverstone-2020-The glucosyltransferase activ,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17402,PHI:10932,UniProt,P16154,GenBank,CAA36094,,,VPI 10463,tcdA,,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,cecum,toxin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32960931,PubMed,10.1371/journal.ppat.1008852,PLoS Pathog. 2020 Sep 22;16(9):e1008852,roman.melnyk@sickkids.ca,TcdB glucosyltransferase activity was indispensable for disease pathogenesis.,T W Bilverstone 2020,2020,2 genes,Bilverstone-2020-The glucosyltransferase activ,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17403,PHI:10933,UniProt,Q63SC0,GenBank,CAH36407,,,K96243,plc1 (bpsl2404),chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,periplasmic ligand binding lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17404,PHI:10934,UniProt,Q63Y51,GenBank,CAH34326,,,K96243,plc2 (bpsl0337),chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,MutT/NUDIX family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17405,PHI:10935,UniProt,Q63P76,GenBank,CAH37512,,,K96243,plc3 (bpss0068),chromosome 2,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17406,PHI:10933,UniProt,Q63SC0,GenBank,CAH36407,,,K96243,plc1 (bpsl2404),chromosome 1,,,,,PHI:10934,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,periplasmic ligand binding lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17407,PHI:10934,UniProt,Q63Y51,GenBank,CAH34326,,,K96243,plc2 (bpsl0337),chromosome 1,,,,,PHI:10933,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,MutT/NUDIX family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17408,PHI:10933,UniProt,Q63SC0,GenBank,CAH36407,,,K96243,plc1 (bpsl2404),chromosome 1,,,,,PHI:10934; PHI:10935,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,periplasmic ligand binding lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17409,PHI:10934,UniProt,Q63Y51,GenBank,CAH34326,,,K96243,plc2 (bpsl0337),chromosome 1,,,,,PHI:10933; PHI:10935,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,MutT/NUDIX family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17410,PHI:10935,UniProt,Q63P76,GenBank,CAH37512,,,K96243,plc3 (bpss0068),chromosome 2,,,,,PHI:10933; PHI:10934,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17411,PHI:10933,UniProt,Q63SC0,GenBank,CAH36407,,,K96243,plc1 (bpsl2404),chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,periplasmic ligand binding lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17412,PHI:10934,UniProt,Q63Y51,GenBank,CAH34326,,,K96243,plc2 (bpsl0337),chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,MutT/NUDIX family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17413,PHI:10935,UniProt,Q63P76,GenBank,CAH37512,,,K96243,plc3 (bpss0068),chromosome 2,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17414,PHI:10933,UniProt,Q63SC0,GenBank,CAH36407,,,K96243,plc1 (bpsl2404),chromosome 1,,,,,PHI:10934,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,periplasmic ligand binding lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17415,PHI:10934,UniProt,Q63Y51,GenBank,CAH34326,,,K96243,plc2 (bpsl0337),chromosome 1,,,,,PHI:10933,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,MutT/NUDIX family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17416,PHI:10933,UniProt,Q63SC0,GenBank,CAH36407,,,K96243,plc1 (bpsl2404),chromosome 1,,,,,PHI:10934; PHI:10935,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,periplasmic ligand binding lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17417,PHI:10934,UniProt,Q63Y51,GenBank,CAH34326,,,K96243,plc2 (bpsl0337),chromosome 1,,,,,PHI:10933; PHI:10935,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,MutT/NUDIX family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17418,PHI:10935,UniProt,Q63P76,GenBank,CAH37512,,,K96243,plc3 (bpss0068),chromosome 2,,,,,PHI:10933; PHI:10934,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"The plc2, plc12 or plc123 mutants showed reduced intracellular survival in macrophages and reduced plaque formation in HeLa cells.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17419,PHI:10933,UniProt,Q63SC0,GenBank,CAH36407,,,K96243,plc1 (bpsl2404),chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,periplasmic ligand binding lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"In Galleria mellonella, plc1, plc2 or plc3 mutants were not attenuated compared to the wild-type strain, but multiple plc mutants showed reduced virulence.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17420,PHI:10934,UniProt,Q63Y51,GenBank,CAH34326,,,K96243,plc2 (bpsl0337),chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MutT/NUDIX family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"In Galleria mellonella, plc1, plc2 or plc3 mutants were not attenuated compared to the wild-type strain, but multiple plc mutants showed reduced virulence.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17421,PHI:10935,UniProt,Q63P76,GenBank,CAH37512,,,K96243,plc3 (bpss0068),chromosome 2,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"In Galleria mellonella, plc1, plc2 or plc3 mutants were not attenuated compared to the wild-type strain, but multiple plc mutants showed reduced virulence.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17422,PHI:10933,UniProt,Q63SC0,GenBank,CAH36407,,,K96243,plc1 (bpsl2404),chromosome 1,,,,,PHI:10934,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,periplasmic ligand binding lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"In Galleria mellonella, plc1, plc2 or plc3 mutants were not attenuated compared to the wild-type strain, but multiple plc mutants showed reduced virulence.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17423,PHI:10934,UniProt,Q63Y51,GenBank,CAH34326,,,K96243,plc2 (bpsl0337),chromosome 1,,,,,PHI:10933,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MutT/NUDIX family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"In Galleria mellonella, plc1, plc2 or plc3 mutants were not attenuated compared to the wild-type strain, but multiple plc mutants showed reduced virulence.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17424,PHI:10933,UniProt,Q63SC0,GenBank,CAH36407,,,K96243,plc1 (bpsl2404),chromosome 1,,,,,PHI:10934; PHI:10935,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,periplasmic ligand binding lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"In Galleria mellonella, plc1, plc2 or plc3 mutants were not attenuated compared to the wild-type strain, but multiple plc mutants showed reduced virulence.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17425,PHI:10934,UniProt,Q63Y51,GenBank,CAH34326,,,K96243,plc2 (bpsl0337),chromosome 1,,,,,PHI:10933; PHI:10935,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,MutT/NUDIX family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"In Galleria mellonella, plc1, plc2 or plc3 mutants were not attenuated compared to the wild-type strain, but multiple plc mutants showed reduced virulence.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17426,PHI:10935,UniProt,Q63P76,GenBank,CAH37512,,,K96243,plc3 (bpss0068),chromosome 2,,,,,PHI:10933; PHI:10934,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33159122,PubMed,10.1038/s41598-020-76186-z,Sci Rep. 2020 Nov 6;10(1):19242,Sunee.kor@mahidol.edu,"In Galleria mellonella, plc1, plc2 or plc3 mutants were not attenuated compared to the wild-type strain, but multiple plc mutants showed reduced virulence.",V Srinon 2020,2020,3 genes,Srinon-2020-Functional redundancy of Burkholde,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17427,PHI:10936,UniProt,Q18C42,GenBank,CAJ68387,,,630,pgdA (CD630_15220),,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,putative polysaccharide deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978253,PubMed,10.1074/jbc.RA119.012442,J Biol Chem. 2020 Sep 25:jbc.RA119.012442,thomas.candela@u-psud.fr,Lack of N-deacetylation in C. difficile was not linked to a decrease in virulence.,H Coullon 2020,2020,3 genes,Coullon-2020-Peptidoglycan analysis reveals th,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17428,PHI:10937,UniProt,Q180A0,GenBank,CAJ70154,,,630,pgdB (CD630_32570),,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,glucosamine N-deacetylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978253,PubMed,10.1074/jbc.RA119.012442,J Biol Chem. 2020 Sep 25:jbc.RA119.012442,thomas.candela@u-psud.fr,Lack of N-deacetylation in C. difficile was not linked to a decrease in virulence.,H Coullon 2020,2020,3 genes,Coullon-2020-Peptidoglycan analysis reveals th,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17429,PHI:10936,UniProt,Q18C42,GenBank,CAJ68387,,,630,pgdA (CD630_15220),,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,putative polysaccharide deacetylase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978253,PubMed,10.1074/jbc.RA119.012442,J Biol Chem. 2020 Sep 25:jbc.RA119.012442,thomas.candela@u-psud.fr,Lack of N-deacetylation in C. difficile was not linked to a decrease in virulence.,H Coullon 2020,2020,3 genes,Coullon-2020-Peptidoglycan analysis reveals th,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17430,PHI:10938,UniProt,Q18C76,GenBank,CAJ68421,,,630,pdaV (CD630_15560),,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,putative polysaccharide deacetylase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978253,PubMed,10.1074/jbc.RA119.012442,J Biol Chem. 2020 Sep 25:jbc.RA119.012442,thomas.candela@u-psud.fr,Lack of N-deacetylation in C. difficile was not linked to a decrease in virulence.,H Coullon 2020,2020,3 genes,Coullon-2020-Peptidoglycan analysis reveals th,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17431,PHI:10937,UniProt,Q180A0,GenBank,CAJ70154,,,630,pgdB (CD630_32570),,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,glucosamine N-deacetylase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978253,PubMed,10.1074/jbc.RA119.012442,J Biol Chem. 2020 Sep 25:jbc.RA119.012442,thomas.candela@u-psud.fr,Lack of N-deacetylation in C. difficile was not linked to a decrease in virulence.,H Coullon 2020,2020,3 genes,Coullon-2020-Peptidoglycan analysis reveals th,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17432,PHI:10936,UniProt,Q18C42,GenBank,CAJ68387,,,630,pgdA (CD630_15220),,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,putative polysaccharide deacetylase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978253,PubMed,10.1074/jbc.RA119.012442,J Biol Chem. 2020 Sep 25:jbc.RA119.012442,thomas.candela@u-psud.fr,Lack of N-deacetylation in C. difficile was not linked to a decrease in virulence.,H Coullon 2020,2020,3 genes,Coullon-2020-Peptidoglycan analysis reveals th,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17433,PHI:10938,UniProt,Q18C76,GenBank,CAJ68421,,,630,pdaV (CD630_15560),,,,,,,1496,Clostridioides difficile,272563,630Δerm,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,putative polysaccharide deacetylase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32978253,PubMed,10.1074/jbc.RA119.012442,J Biol Chem. 2020 Sep 25:jbc.RA119.012442,thomas.candela@u-psud.fr,Lack of N-deacetylation in C. difficile was not linked to a decrease in virulence.,H Coullon 2020,2020,3 genes,Coullon-2020-Peptidoglycan analysis reveals th,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17434,PHI:10939,UniProt,Q888L0,GenBank,AAO54541,,,DC3000,PSPTO_1008,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33029921,PubMed,10.1111/mpp.13001,Mol Plant Pathol. 2020 Dec;21(12):1606-1619,emilia.lopez@upm.es,The inactivation of PSPTO_1008 and PSPTO_2526 chemoreceptors caused a reduction in virulence.,S Santamaría-Hernando 2020,2020,5 genes,Santamaria-Hern-2020-Blue-light perception by,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17435,PHI:10940,UniProt,Q882U6,GenBank,AAO56033,,,DC3000,PSPTO_2526,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33029921,PubMed,10.1111/mpp.13001,Mol Plant Pathol. 2020 Dec;21(12):1606-1619,emilia.lopez@upm.es,The inactivation of PSPTO_1008 and PSPTO_2526 chemoreceptors caused a reduction in virulence.,S Santamaría-Hernando 2020,2020,5 genes,Santamaria-Hern-2020-Blue-light perception by,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17436,PHI:10941,UniProt,Q886T3,GenBank,AAO55014,,,DC3000,PSPTO_1493,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,methyl-accepting chemotaxis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33029921,PubMed,10.1111/mpp.13001,Mol Plant Pathol. 2020 Dec;21(12):1606-1619,emilia.lopez@upm.es,The inactivation of PSPTO_1008 and PSPTO_2526 chemoreceptors caused a reduction in virulence.,S Santamaría-Hernando 2020,2020,5 genes,Santamaria-Hern-2020-Blue-light perception by,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17437,PHI:10942,UniProt,Q87WK5,GenBank,AAO57989,,,DC3000,PSPTO_4541,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,methyl-accepting chemotaxis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33029921,PubMed,10.1111/mpp.13001,Mol Plant Pathol. 2020 Dec;21(12):1606-1619,emilia.lopez@upm.es,The inactivation of PSPTO_1008 and PSPTO_2526 chemoreceptors caused a reduction in virulence.,S Santamaría-Hernando 2020,2020,5 genes,Santamaria-Hern-2020-Blue-light perception by,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17438,PHI:10943,UniProt,Q87UE7,GenBank,AAO58777,,,DC3000,PSPTO_5352,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,methyl-accepting chemotaxis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33029921,PubMed,10.1111/mpp.13001,Mol Plant Pathol. 2020 Dec;21(12):1606-1619,emilia.lopez@upm.es,The inactivation of PSPTO_1008 and PSPTO_2526 chemoreceptors caused a reduction in virulence.,S Santamaría-Hernando 2020,2020,5 genes,Santamaria-Hern-2020-Blue-light perception by,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17439,PHI:10944,UniProt,Q46942,GenBank,AAB40494,,,MG1655,YqeI,,,,,,,562,Escherichia coli,,AE81,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,heart; liver; spleen; lung,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32947771,PubMed,10.3390/ani10091658,Animals (Basel). 2020 Sep 16;10(9):1658,qkz@ahau.edu.cn,"The absence of yqeI decreased the bacterial flagella formation ability, motility ability, antiserum bactericidal ability, adhesion ability and colonization ability.",M Xue 2020,2020,1 gene,"Xue-2020-Transcriptional Regulator YqeI, Locat",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17440,PHI:10944,UniProt,Q46942,GenBank,AAB40494,,,MG1655,YqeI,,,,,,,562,Escherichia coli,,AE81,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,UMNSAH/DF-1 cell,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32947771,PubMed,10.3390/ani10091658,Animals (Basel). 2020 Sep 16;10(9):1658,qkz@ahau.edu.cn,"The absence of yqeI decreased the bacterial flagella formation ability, motility ability, antiserum bactericidal ability, adhesion ability and colonization ability.",M Xue 2020,2020,1 gene,"Xue-2020-Transcriptional Regulator YqeI, Locat",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17441,PHI:10945,UniProt,Q8XZP4,GenBank,CAD15053,,,GMI1000,RSc1351 (phcK),,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,root,putative sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33025726,PubMed,10.1111/mpp.12998,Mol Plant Pathol. 2020 Dec;21(12):1591-1605,yhikichi@kochi-u.ac.jp,RSc1351 (phcK) transposon mutant exhibited significantly decreased cell aggregation activity.,W Senuma 2020,2020,1 gene,Senuma-2020-The putative sensor histidine kina,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17442,PHI:10946,UniProt,Q9I1W9,GenBank,AE004642_1,,,PAO1,PA2146,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,conserved hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33134189,PubMed,10.3389/fcimb.2020.559803,Front Cell Infect Microbiol. 2020 Oct 7;10:559803,wuyong_zn@csu.edu.cn,The production of cytokines in RAW264.7 cells and THP-1 cells were also significantly decreased after stimulated with PA2146 deleted PAO1 than its wild type.,P She 2020,2020,1 gene,She-2020-PA2146 Gene Knockout Is Associated Wi,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17443,PHI:10946,UniProt,Q9I1W9,GenBank,AE004642_1,,,PAO1,PA2146,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,conserved hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33134189,PubMed,10.3389/fcimb.2020.559803,Front Cell Infect Microbiol. 2020 Oct 7;10:559803,wuyong_zn@csu.edu.cn,The production of cytokines in RAW264.7 cells and THP-1 cells were also significantly decreased after stimulated with PA2146 deleted PAO1 than its wild type.,P She 2020,2020,1 gene,She-2020-PA2146 Gene Knockout Is Associated Wi,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17444,PHI:10946,UniProt,Q9I1W9,GenBank,AE004642_1,,,PAO1,PA2146,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,conserved hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33134189,PubMed,10.3389/fcimb.2020.559803,Front Cell Infect Microbiol. 2020 Oct 7;10:559803,wuyong_zn@csu.edu.cn,PAO1ΔPA2146 inhibited cytokine secretion in the lungs but increased the infiltration of inflammatory cells compared to the wild-type group.,P She 2020,2020,1 gene,She-2020-PA2146 Gene Knockout Is Associated Wi,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17445,PHI:10947,UniProt,E9EYM0,GenBank,EFY99061,,,ARSEF 23,GLYK (MAA_05119),chromosome 6,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,,glycerate-3-kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,SDS; Congo red; calcofluor white,SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33128436,PubMed,10.1002/ps.6165,Pest Manag Sci. 2020 Oct 31,lkang@ioz.ac.cn,Topical infection and injection of Ma::MrGLYK significantly increased the mortality and shortened the lifespan of locusts compared with wild-type M. acridum.,X Tong 2020,2020,1 gene,Tong-2020-Transformation of glycerate kinase (,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17446,PHI:10948,UniProt,A0A1R3RLQ3,GenBank,OOF95411,,,ITEM 5010,LaeA,,,,,,,40993,Aspergillus carbonarius,,NRRL 368,rot (grape),eudicots,3760,Prunus persica (related: peach),var. nucipersica cv. Sun Snow,,,fruit,hypothetical protein,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33169928,PubMed,10.1111/mpp.13013,Mol Plant Pathol. 2020 Nov 10,edwardsio@volcani.agri.gov.il,Loss of AcLaeA affected fruit colonization.,U Maor 2020,2020,3 genes,"Maor-2020-Functional roles of LaeA, polyketide",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17447,PHI:10949,UniProt,A0A1R3RM75,GenBank,OOF95573,,,ITEM 5010,GOX,,,,,,,40993,Aspergillus carbonarius,,NRRL 368,rot (grape),eudicots,3760,Prunus persica (related: peach),var. nucipersica cv. Sun Snow,,,fruit,GMC oxidoreductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33169928,PubMed,10.1111/mpp.13013,Mol Plant Pathol. 2020 Nov 10,edwardsio@volcani.agri.gov.il,AcGOX was required for A. carbonarius pathogenicity in deciduous fruit.,U Maor 2020,2020,3 genes,"Maor-2020-Functional roles of LaeA, polyketide",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17448,PHI:10950,UniProt,A0A1R3RGK0,GenBank,OOF93599,,,ITEM 5010,pks,,,,,,,40993,Aspergillus carbonarius,,NRRL 368,rot (grape),eudicots,3760,Prunus persica (related: peach),var. nucipersica cv. Sun Snow,,,fruit,ochratoxin highly reducing polyketide synthase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33169928,PubMed,10.1111/mpp.13013,Mol Plant Pathol. 2020 Nov 10,edwardsio@volcani.agri.gov.il,The Acpks-knockout mutant did not contribute to A. carbonarius pathogenicity.,U Maor 2020,2020,3 genes,"Maor-2020-Functional roles of LaeA, polyketide",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17449,PHI:10948,UniProt,A0A1R3RLQ3,GenBank,OOF95411,,,ITEM 5010,LaeA,,,,,,,40993,Aspergillus carbonarius,,NRRL 368,rot (grape),eudicots,29760,Vitis vinifera (related: wine grape),cv. Zani,,,fruit,hypothetical protein,,,,reduced virulence,,,,,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33169928,PubMed,10.1111/mpp.13013,Mol Plant Pathol. 2020 Nov 10,edwardsio@volcani.agri.gov.il,Loss of AcLaeA affected fruit colonization.,U Maor 2020,2020,3 genes,"Maor-2020-Functional roles of LaeA, polyketide",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17450,PHI:10949,UniProt,A0A1R3RM75,GenBank,OOF95573,,,ITEM 5010,GOX,,,,,,,40993,Aspergillus carbonarius,,NRRL 368,rot (grape),eudicots,29760,Vitis vinifera (related: wine grape),cv. Zani,,,fruit,GMC oxidoreductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33169928,PubMed,10.1111/mpp.13013,Mol Plant Pathol. 2020 Nov 10,edwardsio@volcani.agri.gov.il,AcGOX was required for A. carbonarius pathogenicity in deciduous fruit.,U Maor 2020,2020,3 genes,"Maor-2020-Functional roles of LaeA, polyketide",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17451,PHI:10950,UniProt,A0A1R3RGK0,GenBank,OOF93599,,,ITEM 5010,pks,,,,,,,40993,Aspergillus carbonarius,,NRRL 368,rot (grape),eudicots,29760,Vitis vinifera (related: wine grape),cv. Zani,,,fruit,ochratoxin highly reducing polyketide synthase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33169928,PubMed,10.1111/mpp.13013,Mol Plant Pathol. 2020 Nov 10,edwardsio@volcani.agri.gov.il,The Acpks-knockout mutant did not contribute to A. carbonarius pathogenicity.,U Maor 2020,2020,3 genes,"Maor-2020-Functional roles of LaeA, polyketide",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17452,PHI:10951,,no data found,,,,,,Mlp124357,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,32947987,PubMed,10.3390/biology9090294,Biology (Basel). 2020 Sep 16;9(9):294,hugo.germain@uqtr.ca,Constitutive expression of the eector increased plant susceptibility to pathogens.,M H Madina 2020,2020,1 gene,Madina-2020-A Poplar Rust Effector Protein Ass,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17453,PHI:10952,UniProt,G4ZHR2,GenBank,EGZ16757,,,P6497,PsXEG1,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33082226,PubMed,10.1073/pnas.2012149117,Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27685-27693,wangyc@njau.edu.cn,Host gene alteration data avaialble for GmAP5. Silencing of GmAP5 reduced soybean resistance against WT P. sojae but not against PsXEG1 deletion strains of P. sojae.,Y Xia 2020,2020,1 gene,Xia-2020-N-glycosylation shields Phytophthora,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17454,PHI:10952,UniProt,G4ZHR2,GenBank,EGZ16757,,,P6497,PsXEG1,,PsXEG1 N174A&N190A,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33082226,PubMed,10.1073/pnas.2012149117,Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27685-27693,wangyc@njau.edu.cn,Host gene alteration data avaialble for GmAP5. The binding affinity of PsXEG1 to GmGIP1 was attenuated by N-glycosylation.,Y Xia 2020,2020,1 gene,Xia-2020-N-glycosylation shields Phytophthora,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17455,PHI:10953,UniProt,A0A4V1DMY4,GenBank,AE005523_3,,,EDL933,lmiA (z4267),,,,,,,562,Escherichia coli,,serotype O157:H7,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,DNA-binding protein,,,,reduced virulence,,,,,,,,,,no,MgCl2,MgCl2: CHEBI:6636,,,,,gene deletion: full; gene complementation,,,YVS,33173003,PubMed,10.1128/mBio.02470-20,mBio. 2020 Nov 10;11(6):e02470-20,yangbin@nankai.edu.cn,Feeding mice a magnesium-rich diet had no clear effects on adherence of these mutants in the mouse intestinal tract.,Y Liu 2020,2020,3 genes,Liu-2020-Magnesium Sensing Regulates Intestina,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17456,PHI:10954,UniProt,P23837,GenBank,BAA14391,,,K-12,phoQ,,,,,,,562,Escherichia coli,,serotype O157:H7,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,sensor protein,,,,reduced virulence,,,,,,,,,,no,MgCl2,MgCl2: CHEBI:6636,,,,,gene deletion: full; gene complementation,,,YVS,33173003,PubMed,10.1128/mBio.02470-20,mBio. 2020 Nov 10;11(6):e02470-20,yangbin@nankai.edu.cn,Feeding mice a magnesium-rich diet had no clear effects on adherence of these mutants in the mouse intestinal tract.,Y Liu 2020,2020,3 genes,Liu-2020-Magnesium Sensing Regulates Intestina,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17457,PHI:10955,UniProt,P23836,GenBank,BAA14390,,,K-12,phoP,,,,,,,562,Escherichia coli,,serotype O157:H7,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,MgCl2,MgCl2: CHEBI:6636,,,,,gene deletion: full; gene complementation,,,YVS,33173003,PubMed,10.1128/mBio.02470-20,mBio. 2020 Nov 10;11(6):e02470-20,yangbin@nankai.edu.cn,Feeding mice a magnesium-rich diet had no clear effects on adherence of these mutants in the mouse intestinal tract.,Y Liu 2020,2020,3 genes,Liu-2020-Magnesium Sensing Regulates Intestina,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17458,PHI:10956,UniProt,B8K2M5,GenBank,ABF68764,,,BCRC11901,phoQ,,,,,,PHI:10957,40324,Stenotrophomonas maltophilia,,KJ,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,two-component regulatory system-histidine kinase,,,,reduced virulence,,,,,,,,,,no,"beta-lactam; quinolone; aminoglycoside; macrolide; chloramphenicol; sulfamethoxazole; trimethoprim; menadione; H2O2; SDS; 2,2'-dipyridyl","beta-lactam: CHEBI:27933; quinolone: CHEBI:86324; aminoglycoside: CHEBI:22507; macrolide: CHEBI:25105; chloramphenicol: CHEBI:17698; sulfamethoxazole: CHEBI:9332; trimethoprim: CHEBI:45924; menadione: CHEBI:28869; H2O2: CHEBI:16240; SDS: CHEBI:8984; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,33054754,PubMed,10.1186/s12866-020-01989-z,BMC Microbiol. 2020 Oct 14;20(1):312,tcyang@ym.edu.tw,"KJΔPhoPQ totally lost swimming motility, had enhanced secreted protease activity, increased susceptibility to antibiotics, menadione, H2O2, SDS, and 2,2'dipyridyl, as well as attenuated virulence to C. elegans.",H F Lu 2020,2020,2 genes,Lu-2020-PhoPQ two-component regulatory system,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17459,PHI:10957,UniProt,B8K2M4,GenBank,ABF68763,,,BCRC11901,phoP,,,,,,PHI:10956,40324,Stenotrophomonas maltophilia,,KJ,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,two-component regulatory system-DNA-binding response regulator,,,,reduced virulence,,,,,,,,,,no,"beta-lactam; quinolone; aminoglycoside; macrolide; chloramphenicol; sulfamethoxazole; trimethoprim; menadione; H2O2; SDS; 2,2'-dipyridyl","beta-lactam: CHEBI:27933; quinolone: CHEBI:86324; aminoglycoside: CHEBI:22507; macrolide: CHEBI:25105; chloramphenicol: CHEBI:17698; sulfamethoxazole: CHEBI:9332; trimethoprim: CHEBI:45924; menadione: CHEBI:28869; H2O2: CHEBI:16240; SDS: CHEBI:8984; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,33054754,PubMed,10.1186/s12866-020-01989-z,BMC Microbiol. 2020 Oct 14;20(1):312,tcyang@ym.edu.tw,"KJΔPhoPQ totally lost swimming motility, had enhanced secreted protease activity, increased susceptibility to antibiotics, menadione, H2O2, SDS, and 2,2'dipyridyl, as well as attenuated virulence to C. elegans.",H F Lu 2020,2020,2 genes,Lu-2020-PhoPQ two-component regulatory system,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17460,PHI:10958,,no data found,,,,,,ena1a,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,P-type IID/ENA Na+/K+ ATPases,,,,reduced virulence,,,yes,,,wild type,,wild type,reduced,no,NaCl; LiCl; KCl; sorbitol; menadione; H2O2; Congo red; calcofluor white; ZnSO4; MnSO4; CuSO4; FeCl3,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; sorbitol: CHEBI:30911; menadione: CHEBI:28869; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; ZnSO4: CHEBI:35176; MnSO4 CAS no.: CAS:7785-87-7; CuSO4: CHEBI:23414; FeCl3: CHEBI:30808,,,,,gene deletion: full; gene complementation,,,YVS,33103596,PubMed,10.1080/21505594.2020.1836903,Virulence. 2020 Dec;11(1):1415-1431,tongsm@zafu.edu.cn,"The Δena1a and Δena2b mutants were less tolerant to metal cations (Na+, K+, Li+, Zn2+, Mn2+ and Fe3+), cell wall perturbation, oxidation, non-cation hyperosmolarity and UVB irradiation, severely compromised in insect pathogenicity via normal cuticle infection, and attenuated in virulence via hemocoel injection.",Y N Mou 2020,2020,7 genes,Mou-2020-P-type Na(+)_K(+) ATPases essential a,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17461,PHI:10959,,no data found,,,,,,ena2b,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,P-type IID/ENA Na+/K+ ATPases,,,,reduced virulence,,,yes,,,wild type,,wild type,reduced,no,NaCl; LiCl; KCl; sorbitol; menadione; H2O2; Congo red; calcofluor white; ZnSO4; MnSO4; CuSO4; FeCl3,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; sorbitol: CHEBI:30911; menadione: CHEBI:28869; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; ZnSO4: CHEBI:35176; MnSO4 CAS no.: CAS:7785-87-7; CuSO4: CHEBI:23414; FeCl3: CHEBI:30808,,,,,gene deletion: full; gene complementation,,,YVS,33103596,PubMed,10.1080/21505594.2020.1836903,Virulence. 2020 Dec;11(1):1415-1431,tongsm@zafu.edu.cn,"The Δena1a and Δena2b mutants were less tolerant to metal cations (Na+, K+, Li+, Zn2+, Mn2+ and Fe3+), cell wall perturbation, oxidation, non-cation hyperosmolarity and UVB irradiation, severely compromised in insect pathogenicity via normal cuticle infection, and attenuated in virulence via hemocoel injection.",Y N Mou 2020,2020,7 genes,Mou-2020-P-type Na(+)_K(+) ATPases essential a,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17462,PHI:10960,,no data found,,,,,,ena1b,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,P-type IID/ENA Na+/K+ ATPases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; LiCl; KCl; sorbitol; menadione; H2O2; Congo red; calcofluor white; ZnSO4; MnSO4; CuSO4; FeCl3,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; sorbitol: CHEBI:30911; menadione: CHEBI:28869; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; ZnSO4: CHEBI:35176; MnSO4 CAS no.: CAS:7785-87-7; CuSO4: CHEBI:23414; FeCl3: CHEBI:30808,,,,,gene deletion: full; gene complementation,,,YVS,33103596,PubMed,10.1080/21505594.2020.1836903,Virulence. 2020 Dec;11(1):1415-1431,tongsm@zafu.edu.cn,"The Δena1a and Δena2b mutants were less tolerant to metal cations (Na+, K+, Li+, Zn2+, Mn2+ and Fe3+), cell wall perturbation, oxidation, non-cation hyperosmolarity and UVB irradiation, severely compromised in insect pathogenicity via normal cuticle infection, and attenuated in virulence via hemocoel injection.",Y N Mou 2020,2020,7 genes,Mou-2020-P-type Na(+)_K(+) ATPases essential a,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17463,PHI:10961,,no data found,,,,,,ena1c,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,P-type IID/ENA Na+/K+ ATPases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; LiCl; KCl; sorbitol; menadione; H2O2; Congo red; calcofluor white; ZnSO4; MnSO4; CuSO4; FeCl3,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; sorbitol: CHEBI:30911; menadione: CHEBI:28869; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; ZnSO4: CHEBI:35176; MnSO4 CAS no.: CAS:7785-87-7; CuSO4: CHEBI:23414; FeCl3: CHEBI:30808,,,,,gene deletion: full; gene complementation,,,YVS,33103596,PubMed,10.1080/21505594.2020.1836903,Virulence. 2020 Dec;11(1):1415-1431,tongsm@zafu.edu.cn,"The Δena1a and Δena2b mutants were less tolerant to metal cations (Na+, K+, Li+, Zn2+, Mn2+ and Fe3+), cell wall perturbation, oxidation, non-cation hyperosmolarity and UVB irradiation, severely compromised in insect pathogenicity via normal cuticle infection, and attenuated in virulence via hemocoel injection.",Y N Mou 2020,2020,7 genes,Mou-2020-P-type Na(+)_K(+) ATPases essential a,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17464,PHI:10962,,no data found,,,,,,ena2a,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,P-type IID/ENA Na+/K+ ATPases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; LiCl; KCl; sorbitol; menadione; H2O2; Congo red; calcofluor white; ZnSO4; MnSO4; CuSO4; FeCl3,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; sorbitol: CHEBI:30911; menadione: CHEBI:28869; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; ZnSO4: CHEBI:35176; MnSO4 CAS no.: CAS:7785-87-7; CuSO4: CHEBI:23414; FeCl3: CHEBI:30808,,,,,gene deletion: full; gene complementation,,,YVS,33103596,PubMed,10.1080/21505594.2020.1836903,Virulence. 2020 Dec;11(1):1415-1431,tongsm@zafu.edu.cn,"The Δena1a and Δena2b mutants were less tolerant to metal cations (Na+, K+, Li+, Zn2+, Mn2+ and Fe3+), cell wall perturbation, oxidation, non-cation hyperosmolarity and UVB irradiation, severely compromised in insect pathogenicity via normal cuticle infection, and attenuated in virulence via hemocoel injection.",Y N Mou 2020,2020,7 genes,Mou-2020-P-type Na(+)_K(+) ATPases essential a,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17465,PHI:10963,,no data found,,,,,,nk1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,P-type IIC/NK Na+/K+ ATPases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; LiCl; KCl; sorbitol; menadione; H2O2; Congo red; calcofluor white; ZnSO4; MnSO4; CuSO4; FeCl3,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; sorbitol: CHEBI:30911; menadione: CHEBI:28869; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; ZnSO4: CHEBI:35176; MnSO4 CAS no.: CAS:7785-87-7; CuSO4: CHEBI:23414; FeCl3: CHEBI:30808,,,,,gene deletion: full; gene complementation,,,YVS,33103596,PubMed,10.1080/21505594.2020.1836903,Virulence. 2020 Dec;11(1):1415-1431,tongsm@zafu.edu.cn,"The Δena1a and Δena2b mutants were less tolerant to metal cations (Na+, K+, Li+, Zn2+, Mn2+ and Fe3+), cell wall perturbation, oxidation, non-cation hyperosmolarity and UVB irradiation, severely compromised in insect pathogenicity via normal cuticle infection, and attenuated in virulence via hemocoel injection.",Y N Mou 2020,2020,7 genes,Mou-2020-P-type Na(+)_K(+) ATPases essential a,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17466,PHI:10964,,no data found,,,,,,nk2,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,P-type IIC/NK Na+/K+ ATPases,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; LiCl; KCl; sorbitol; menadione; H2O2; Congo red; calcofluor white; ZnSO4; MnSO4; CuSO4; FeCl3,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; sorbitol: CHEBI:30911; menadione: CHEBI:28869; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; ZnSO4: CHEBI:35176; MnSO4 CAS no.: CAS:7785-87-7; CuSO4: CHEBI:23414; FeCl3: CHEBI:30808,,,,,gene deletion: full; gene complementation,,,YVS,33103596,PubMed,10.1080/21505594.2020.1836903,Virulence. 2020 Dec;11(1):1415-1431,tongsm@zafu.edu.cn,"The Δena1a and Δena2b mutants were less tolerant to metal cations (Na+, K+, Li+, Zn2+, Mn2+ and Fe3+), cell wall perturbation, oxidation, non-cation hyperosmolarity and UVB irradiation, severely compromised in insect pathogenicity via normal cuticle infection, and attenuated in virulence via hemocoel injection.",Y N Mou 2020,2020,7 genes,Mou-2020-P-type Na(+)_K(+) ATPases essential a,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17467,PHI:10965,UniProt,P06619,GenBank,CAA27315,,,1006 pv. savastanoi,ptz,,,,,,,29438,Pseudomonas savastanoi,693985,NCPPB 3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,isopentenyl transferase,,,cytokinin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32973852,PubMed,10.3389/fpls.2020.01294,Front Plant Sci. 2020 Aug 21;11:1294,jesus.murillo@unavarra.es,"Strains lacking ptz, idi, or both produced tumors with average volumes up to 29 times smaller and reached populations up to two orders of magnitude lower than those induced by strain NCPPB3335.",M Añorga 2020,2020,2 genes,"Añorga-2020-Genes ptz and idi, Coding for Cyto",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17468,PHI:10966,UniProt,A0A3M5LJ40,GenBank,RMS74286,,,ICMP 13928,idi,,,,,,,29438,Pseudomonas savastanoi,693985,NCPPB 3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,isopentenyl-diphosphate delta-isomerase,,,cytokinin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32973852,PubMed,10.3389/fpls.2020.01294,Front Plant Sci. 2020 Aug 21;11:1294,jesus.murillo@unavarra.es,"Strains lacking ptz, idi, or both produced tumors with average volumes up to 29 times smaller and reached populations up to two orders of magnitude lower than those induced by strain NCPPB3335.",M Añorga 2020,2020,2 genes,"Añorga-2020-Genes ptz and idi, Coding for Cyto",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17469,PHI:10965,UniProt,P06619,GenBank,CAA27315,,,1006 pv. savastanoi,ptz,,,,,,PHI:10966,29438,Pseudomonas savastanoi,693985,NCPPB 3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,isopentenyl transferase,,,cytokinin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32973852,PubMed,10.3389/fpls.2020.01294,Front Plant Sci. 2020 Aug 21;11:1294,jesus.murillo@unavarra.es,"Strains lacking ptz, idi, or both produced tumors with average volumes up to 29 times smaller and reached populations up to two orders of magnitude lower than those induced by strain NCPPB3335.",M Añorga 2020,2020,2 genes,"Añorga-2020-Genes ptz and idi, Coding for Cyto",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17470,PHI:10966,UniProt,A0A3M5LJ40,GenBank,RMS74286,,,ICMP 13928,idi,,,,,,PHI:10965,29438,Pseudomonas savastanoi,693985,NCPPB 3335,knot (olive),eudicots,4146,Olea europaea (related: common olive),cv. Arbequina,,,stem,isopentenyl-diphosphate delta-isomerase,,,cytokinin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32973852,PubMed,10.3389/fpls.2020.01294,Front Plant Sci. 2020 Aug 21;11:1294,jesus.murillo@unavarra.es,"Strains lacking ptz, idi, or both produced tumors with average volumes up to 29 times smaller and reached populations up to two orders of magnitude lower than those induced by strain NCPPB3335.",M Añorga 2020,2020,2 genes,"Añorga-2020-Genes ptz and idi, Coding for Cyto",BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17471,PHI:10967,,no data found,GenBank,ABA45415,,,A909,adcA (SAK_0685),,,,,,,1311,Streptococcus agalactiae,205921,A909,postpartum infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; brain,"zinc ABC transporter, zinc-binding protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33173000,PubMed,10.1128/mBio.02302-20,mBio. 2020 Nov 10;11(6):e02302-20,kelly.doran@cuanschutz.edu,Host gene alteration data avaialble for calprotectin. Global zinc uptake mutant was less virulent than the parental GBS strain and found calprotectin knockout mice to be equally susceptible to infection by wild-type (WT) and mutant strains.,L R Burcham 2020,2020,3 genes,Burcham-2020-Identification of Zinc-Dependent,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17472,PHI:10968,,no data found,GenBank,ABA46061,,,A909,adcAII (SAK_1898),,,,,,,1311,Streptococcus agalactiae,205921,A909,postpartum infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; brain,laminin-binding surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33173000,PubMed,10.1128/mBio.02302-20,mBio. 2020 Nov 10;11(6):e02302-20,kelly.doran@cuanschutz.edu,Host gene alteration data avaialble for calprotectin. Global zinc uptake mutant was less virulent than the parental GBS strain and found calprotectin knockout mice to be equally susceptible to infection by wild-type (WT) and mutant strains.,L R Burcham 2020,2020,3 genes,Burcham-2020-Identification of Zinc-Dependent,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17473,PHI:10969,UniProt,Q9ZHG8,GenBank,AAD13796,,,R268,lmb,,,,,,,1311,Streptococcus agalactiae,205921,A909,postpartum infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; brain,laminin-binding surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33173000,PubMed,10.1128/mBio.02302-20,mBio. 2020 Nov 10;11(6):e02302-20,kelly.doran@cuanschutz.edu,Host gene alteration data avaialble for calprotectin. Global zinc uptake mutant was less virulent than the parental GBS strain and found calprotectin knockout mice to be equally susceptible to infection by wild-type (WT) and mutant strains.,L R Burcham 2020,2020,3 genes,Burcham-2020-Identification of Zinc-Dependent,BATCH_103B,2020-12-01,MC,,,,,,,,,,,,,
,,Record 17474,PHI:10970,UniProt,A0A0H3MCG4,GenBank,CAP03507,,,434/Bu,tmeA (CTL0063),,,,,,,813,Chlamydia trachomatis,,L2,urinary tract infection,primates,9606,Homo sapiens (related: human),human cervical cells,,,keratinocyte,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32946535,PubMed,10.1371/journal.ppat.1008878,PLoS Pathog. 2020 Sep 18;16(9):e1008878. doi: 10.1371/journal.ppat.1008878. eCollection 2020 Sep,mary-weber@uiowa.edu,"While both TmeA and TarP were essential for chlamydial invasion, they targeted distinct cellular pathways that converge on the ARP2/3 complex.",R Faris 2020,2020,2 genes,Faris-2020-The Chlamydia trachomatis secreted,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17475,PHI:10971,UniProt,A0A0H3MJS5,GenBank,CAP03508,,,434/Bu,tmeB (CTL0064),,,,,,,813,Chlamydia trachomatis,,L2,urinary tract infection,primates,9606,Homo sapiens (related: human),human cervical cells,,,keratinocyte,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32946535,PubMed,10.1371/journal.ppat.1008878,PLoS Pathog. 2020 Sep 18;16(9):e1008878. doi: 10.1371/journal.ppat.1008878. eCollection 2020 Sep,mary-weber@uiowa.edu,"While both TmeA and TarP were essential for chlamydial invasion, they targeted distinct cellular pathways that converge on the ARP2/3 complex.",R Faris 2020,2020,2 genes,Faris-2020-The Chlamydia trachomatis secreted,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17476,PHI:10970,UniProt,A0A0H3MCG4,GenBank,CAP03507,,,434/Bu,tmeA (CTL0063),,,,,,PHI:10971,813,Chlamydia trachomatis,,L2,urinary tract infection,primates,9606,Homo sapiens (related: human),human cervical cells,,,keratinocyte,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion full; gene complementation,,,YVS,32946535,PubMed,10.1371/journal.ppat.1008878,PLoS Pathog. 2020 Sep 18;16(9):e1008878. doi: 10.1371/journal.ppat.1008878. eCollection 2020 Sep,mary-weber@uiowa.edu,"While both TmeA and TarP were essential for chlamydial invasion, they targeted distinct cellular pathways that converge on the ARP2/3 complex.",R Faris 2020,2020,2 genes,Faris-2020-The Chlamydia trachomatis secreted,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17477,PHI:10971,UniProt,A0A0H3MJS5,GenBank,CAP03508,,,434/Bu,tmeB (CTL0064),,,,,,PHI:10970,813,Chlamydia trachomatis,,L2,urinary tract infection,primates,9606,Homo sapiens (related: human),human cervical cells,,,keratinocyte,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32946535,PubMed,10.1371/journal.ppat.1008878,PLoS Pathog. 2020 Sep 18;16(9):e1008878. doi: 10.1371/journal.ppat.1008878. eCollection 2020 Sep,mary-weber@uiowa.edu,"While both TmeA and TarP were essential for chlamydial invasion, they targeted distinct cellular pathways that converge on the ARP2/3 complex.",R Faris 2020,2020,2 genes,Faris-2020-The Chlamydia trachomatis secreted,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17478,PHI:10972,UniProt,G2WSJ2,GenBank,EGY17906,,,VdLs.17,VdYap1 (VDAG_01588),chromosome 1,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,269719,Cotinus coggygria (related: smokebush),,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; sodium nitroprusside,H2O2: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene deletion: full; gene complementation,,,YVS,32954659,PubMed,10.1111/mpp.12988,Mol Plant Pathol. 2020 Nov;21(11):1451-1466. doi: 10.1111/mpp.12988. Epub 2020 Sep 20,ylwang@bjfu.edu.cn,VdYap1 contributed to regulation of mature microsclerotia formation and VdAtf1 and VdSkn7 coregulated melanin formation.,C Tang 2020,2020,3 genes,Tang-2020-Convergent and distinctive functions,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17479,PHI:10972,UniProt,G2WSJ2,GenBank,EGY17906,,,VdLs.17,VdYap1 (VDAG_01588),chromosome 1,,,,,PHI:10973,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,269719,Cotinus coggygria (related: smokebush),,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; sodium nitroprusside,H2O2: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene deletion: full; gene complementation,,,YVS,32954659,PubMed,10.1111/mpp.12988,Mol Plant Pathol. 2020 Nov;21(11):1451-1466. doi: 10.1111/mpp.12988. Epub 2020 Sep 20,ylwang@bjfu.edu.cn,VdYap1 contributed to regulation of mature microsclerotia formation and VdAtf1 and VdSkn7 coregulated melanin formation.,C Tang 2020,2020,3 genes,Tang-2020-Convergent and distinctive functions,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17480,PHI:10973,UniProt,G2XEU1,GenBank,EGY18342,,,VdLs.17,VdAtf1 (VDAG_08676),chromosome 2,,,,,PHI:10972,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,269719,Cotinus coggygria (related: smokebush),,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; sodium nitroprusside,H2O2: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene deletion: full; gene complementation,,,YVS,32954659,PubMed,10.1111/mpp.12988,Mol Plant Pathol. 2020 Nov;21(11):1451-1466. doi: 10.1111/mpp.12988. Epub 2020 Sep 20,ylwang@bjfu.edu.cn,VdYap1 contributed to regulation of mature microsclerotia formation and VdAtf1 and VdSkn7 coregulated melanin formation.,C Tang 2020,2020,3 genes,Tang-2020-Convergent and distinctive functions,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17481,PHI:10972,UniProt,G2WSJ2,GenBank,EGY17906,,,VdLs.17,VdYap1 (VDAG_01588),chromosome 1,,,,,PHI:10974,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,269719,Cotinus coggygria (related: smokebush),,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; sodium nitroprusside,H2O2: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene deletion: full; gene complementation,,,YVS,32954659,PubMed,10.1111/mpp.12988,Mol Plant Pathol. 2020 Nov;21(11):1451-1466. doi: 10.1111/mpp.12988. Epub 2020 Sep 20,ylwang@bjfu.edu.cn,VdYap1 contributed to regulation of mature microsclerotia formation and VdAtf1 and VdSkn7 coregulated melanin formation.,C Tang 2020,2020,3 genes,Tang-2020-Convergent and distinctive functions,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17482,PHI:10974,UniProt,G2WVA9,GenBank,EGY20234,,,VdLs.17,VdSkn7 (VDAG_02250),chromosome 7,,,,,PHI:10972,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,269719,Cotinus coggygria (related: smokebush),,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; sodium nitroprusside,H2O2: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene deletion: full; gene complementation,,,YVS,32954659,PubMed,10.1111/mpp.12988,Mol Plant Pathol. 2020 Nov;21(11):1451-1466. doi: 10.1111/mpp.12988. Epub 2020 Sep 20,ylwang@bjfu.edu.cn,VdYap1 contributed to regulation of mature microsclerotia formation and VdAtf1 and VdSkn7 coregulated melanin formation.,C Tang 2020,2020,3 genes,Tang-2020-Convergent and distinctive functions,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17483,PHI:10974,UniProt,G2WVA9,GenBank,EGY20234,,,VdLs.17,VdSkn7 (VDAG_02250),chromosome 7,,,,,PHI:10973,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,269719,Cotinus coggygria (related: smokebush),,,,leaf,transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2; sodium nitroprusside,H2O2: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene deletion: full; gene complementation,,,YVS,32954659,PubMed,10.1111/mpp.12988,Mol Plant Pathol. 2020 Nov;21(11):1451-1466. doi: 10.1111/mpp.12988. Epub 2020 Sep 20,ylwang@bjfu.edu.cn,VdYap1 contributed to regulation of mature microsclerotia formation and VdAtf1 and VdSkn7 coregulated melanin formation.,C Tang 2020,2020,3 genes,Tang-2020-Convergent and distinctive functions,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17484,PHI:10973,UniProt,G2XEU1,GenBank,EGY18342,,,VdLs.17,VdAtf1 (VDAG_08676),chromosome 2,,,,,PHI:10974,27337,Verticillium dahliae,,XS11,vascular wilt,eudicots,269719,Cotinus coggygria (related: smokebush),,,,leaf,transcription factor,,,,reduced virulence,,,,,,,,,,no,H2O2; sodium nitroprusside,H2O2: CHEBI:16240; sodium nitroprusside: CHEBI:29321,,,,,gene deletion: full; gene complementation,,,YVS,32954659,PubMed,10.1111/mpp.12988,Mol Plant Pathol. 2020 Nov;21(11):1451-1466. doi: 10.1111/mpp.12988. Epub 2020 Sep 20,ylwang@bjfu.edu.cn,VdYap1 contributed to regulation of mature microsclerotia formation and VdAtf1 and VdSkn7 coregulated melanin formation.,C Tang 2020,2020,3 genes,Tang-2020-Convergent and distinctive functions,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17485,PHI:10975,UniProt,A0A509AES5,GenBank,VUC54087,,,ANKA,PbSERA4 (PBANKA_0304800),chromosome 3,,,,,,5821,Plasmodium berghei,,NK65,cerebral malaria,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; liver,papain-like cysteine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32956401,PubMed,10.1371/journal.ppat.1008891,PLoS Pathog. 2020 Sep 21;16(9):e1008891. doi: 10.1371/journal.ppat.1008891. eCollection 2020 Sep,alyssa.ingmundson@hu-berlin.de,"Upon transmission from mosquitoes to mice, Pbsera4(-) parasites displayed a reduced capacity to initiate a new round of asexual blood-stage replication.",E D Putrianti 2020,2020,1 gene,Putrianti-2020-A Plasmodium cysteine protease,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17486,PHI:10976,UniProt,Q83D60,GenBank,AAO90413,,,RSA 493,ankG (CBU0881),,,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemocyte,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32958854,PubMed,10.1038/s41598-020-72340-9,Sci Rep. 2020 Sep 21;10(1):15396. doi: 10.1038/s41598-020-72340-9,anja.luehrmann@uk-erlangen.de,"AnkG had the ability to attenuate pathology during in vivo infection, as it allowed survival of the larvae despite bacterial replication.",W Schäfer 2020,2020,2 genes,Schafer-2020-The anti-apoptotic Coxiella burne,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17487,PHI:10977,UniProt,A9KDJ8,GenBank,ABS78182,,,Dugway 5J108-111,dotA,,,,,,,777,Coxiella burnetii,,Nine Mile phase II,Q fever,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemocyte,phagosome trafficking protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,32958854,PubMed,10.1038/s41598-020-72340-9,Sci Rep. 2020 Sep 21;10(1):15396. doi: 10.1038/s41598-020-72340-9,anja.luehrmann@uk-erlangen.de,"AnkG had the ability to attenuate pathology during in vivo infection, as it allowed survival of the larvae despite bacterial replication.",W Schäfer 2020,2020,2 genes,Schafer-2020-The anti-apoptotic Coxiella burne,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17488,PHI:10978,UniProt,A7ZRQ3,GenBank,ABV16661,,,E24377A,sufI,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10036,Mesocricetus auratus (related: golden hamster),BHK-21 cell line,,,BHK-21 cell,cell division protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17489,PHI:10979,UniProt,P36548,GenBank,AAC75488,,,K-12,amiA,,,,,,PHI:10980,562,Escherichia coli,1001989,PCN033,infection,rodents,10036,Mesocricetus auratus (related: golden hamster),BHK-21 cell line,,,BHK-21 cell,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17490,PHI:10980,UniProt,P63883,GenBank,AAC75856,,,K-12,amiC,,,,,,PHI:10979,562,Escherichia coli,1001989,PCN033,infection,rodents,10036,Mesocricetus auratus (related: golden hamster),BHK-21 cell line,,,BHK-21 cell,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17491,PHI:10981,UniProt,P69428,GenBank,AAC76839,,,K-12,tatA,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10036,Mesocricetus auratus (related: golden hamster),BHK-21 cell line,,,BHK-21 cell,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17492,PHI:10982,UniProt,P69425,GenBank,CAA06725,,,K-12,tatB,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10036,Mesocricetus auratus (related: golden hamster),BHK-21 cell line,,,BHK-21 cell,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17493,PHI:10983,UniProt,P69423,GenBank,CAA06726,,,K-12,tatC,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10036,Mesocricetus auratus (related: golden hamster),BHK-21 cell line,,,BHK-21 cell,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17494,PHI:10978,UniProt,A7ZRQ3,GenBank,ABV16661,,,E24377A,sufI,,,,,,,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),PK-15 cell line,,,PK-15 cell,cell division protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17495,PHI:10979,UniProt,P36548,GenBank,AAC75488,,,K-12,amiA,,,,,,PHI:10980,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),PK-15 cell line,,,PK-15 cell,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17496,PHI:10980,UniProt,P63883,GenBank,AAC75856,,,K-12,amiC,,,,,,PHI:10979,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),PK-15 cell line,,,PK-15 cell,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17497,PHI:10981,UniProt,P69428,GenBank,AAC76839,,,K-12,tatA,,,,,,,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),PK-15 cell line,,,PK-15 cell,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17498,PHI:10982,UniProt,P69425,GenBank,CAA06725,,,K-12,tatB,,,,,,,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),PK-15 cell line,,,PK-15 cell,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17499,PHI:10983,UniProt,P69423,GenBank,CAA06726,,,K-12,tatC,,,,,,,562,Escherichia coli,1001989,PCN033,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),PK-15 cell line,,,PK-15 cell,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17500,PHI:10978,UniProt,A7ZRQ3,GenBank,ABV16661,,,E24377A,sufI,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,cell division protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17501,PHI:10979,UniProt,P36548,GenBank,AAC75488,,,K-12,amiA,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17502,PHI:10980,UniProt,P63883,GenBank,AAC75856,,,K-12,amiC,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17503,PHI:10979,UniProt,P36548,GenBank,AAC75488,,,K-12,amiA,,,,,,PHI:10980,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17504,PHI:10980,UniProt,P63883,GenBank,AAC75856,,,K-12,amiC,,,,,,PHI:10979,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,N-acetylmuramoyl-L-alanine amidase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17505,PHI:10981,UniProt,P69428,GenBank,AAC76839,,,K-12,tatA,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17506,PHI:10982,UniProt,P69425,GenBank,CAA06725,,,K-12,tatB,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17507,PHI:10983,UniProt,P69423,GenBank,CAA06726,,,K-12,tatC,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,Sec-independent protein translocase protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17508,PHI:10984,UniProt,P77554,GenBank,AAC73427,,,K-12,yahJ,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,putative deaminase with metallo-dependent hydrolase domain,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17509,PHI:10985,UniProt,P36649,GenBank,AAC73234,,,K-12,cueO,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,blue copper oxidase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17510,PHI:10986,UniProt,P0AAL3,GenBank,AAC75265,,,K-12,napG,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,ferredoxin-type protein,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17511,PHI:10987,UniProt,P30745,GenBank,AAC73868,,,K-12,moaA,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,"GTP 3',8-cyclase",,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17512,PHI:10988,UniProt,J7QMF7,GenBank,AIZ85831,,,94-3024,yagT,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,aldehyde dehydrogenase iron-sulfur subunit,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17513,PHI:10989,UniProt,P07822,GenBank,AAC73263,,,K-12,fhuD,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,iron(III) hydroxamate ABC transporter periplasmic binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17514,PHI:10990,UniProt,P71244,GenBank,AAC75104,,,K-12,wcaM,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,colanic acid biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17515,PHI:10991,UniProt,P0AB24,GenBank,AAC74103,,,K-12,efeO,,,,,,PHI:10992,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,iron uptake system component,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17516,PHI:10992,UniProt,P31545,GenBank,AAC74104,,,K-12,efeB,,,,,,PHI:10991,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,deferrochelatase/peroxidase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17517,PHI:10993,UniProt,P40120,GenBank,AAC74506,,,K-12,mdoD,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,glucans biosynthesis protein D,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17518,PHI:10994,UniProt,P32176,GenBank,AAB03027,,,K-12,fdoG,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,formate dehydrogenase-O major subunit,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17519,PHI:10995,UniProt,P0AAJ8,GenBank,AAC76032,,,K-12,hybA,,,,,,PHI:10996,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,hydrogenase-2 operon protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17520,PHI:10996,UniProt,P69741,GenBank,AAC76033,,,K-12,hybO,,,,,,PHI:10995,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,hydrogenase-2 small chain,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17521,PHI:10997,UniProt,P24183,GenBank,AAD13438,,,K-12,fdnG,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,"formate dehydrogenase, nitrate-inducible, major subunit",,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17522,PHI:10998,UniProt,P77375,GenBank,AAC74741,,,K-12,ydhX,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,putative 4Fe-4S ferredoxin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17523,PHI:10999,UniProt,P0AAK7,GenBank,AAC77042,,,K-12,nrfC,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,putative menaquinol-cytochrome c reductase 4Fe-4S subunit,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17524,PHI:11000,UniProt,P69739,GenBank,AAC74057,,,K-12,hyaA,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,hydrogenase-1 small chain,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17525,PHI:11001,UniProt,P0AB06,GenBank,AAC74012,,,K-12,ycbK,,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),,,,blood; brain; spleen; lung,peptidoglycan LD-endopeptidase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984,,,,,gene deletion: full,,,YVS,32962530,PubMed,10.1080/21505594.2020.1817709,Virulence. 2020 Dec;11(1):1279-1292. doi: 10.1080/21505594.2020.1817709,qhuang@mail.hzau.edu.cn,SufI as well as AmiA and AmiC played an important role in pathogenesis of ExPEC.,J Liu 2020,2020,24 genes,Liu-2020-The Tat system and its dependent cell,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17526,PHI:11002,UniProt,A7EJT3,GenBank,EDO03099,,,1980,SS1G_05578 (SsCTR1),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),cv. Zhongshuang 11,,,leaf,copper transporter,,,,reduced virulence,,,,,,,,,,no,H2O2; CuSO4,H2O2: CHEBI:16240; CuSO4: CHEBI:23414,,,,,altered gene expression / gene regulation: silencing,,,YVS,33002079,PubMed,10.1371/journal.ppat.1008919,PLoS Pathog. 2020 Oct 1;16(10):e1008919. doi: 10.1371/journal.ppat.1008919. eCollection 2020 Oct,qianwei666@hotmail.com,"The lesion size after inoculation with the silenced strains was smaller than those after inoculation with the wild-type strain, while the largest lesion size was observed after inoculation with the overexpression strains in the detached leaves of B. napus, T-DNA mutants, overexpression lines and wild-type line of A. thaliana seedlings.",Y Ding 2020,2020,3 genes,Ding-2020-Sclerotinia sclerotiorum utilizes ho,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17527,PHI:11003,UniProt,A7E480,GenBank,EDN90702,,,1980,SS1G_00102 (SsCCS),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),cv. Zhongshuang 11,,,leaf,superoxide dismutase 1 copper chaperone,,,,reduced virulence,,,,,,,,,,no,H2O2; CuSO4,H2O2: CHEBI:16240; CuSO4: CHEBI:23414,,,,,altered gene expression / gene regulation: silencing,,,YVS,33002079,PubMed,10.1371/journal.ppat.1008919,PLoS Pathog. 2020 Oct 1;16(10):e1008919. doi: 10.1371/journal.ppat.1008919. eCollection 2020 Oct,qianwei666@hotmail.com,"The lesion size after inoculation with the silenced strains was smaller than those after inoculation with the wild-type strain, while the largest lesion size was observed after inoculation with the overexpression strains in the detached leaves of B. napus, T-DNA mutants, overexpression lines and wild-type line of A. thaliana seedlings.",Y Ding 2020,2020,3 genes,Ding-2020-Sclerotinia sclerotiorum utilizes ho,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17528,PHI:11004,UniProt,A7EZX1,GenBank,EDN95013,,,1980,SS1G_10888 (SsATX1),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),cv. Zhongshuang 11,,,leaf,heavy-metal-associated (HMA) domain-containing protein,,,,reduced virulence,,,,,,,,,,no,H2O2; CuSO4,H2O2: CHEBI:16240; CuSO4: CHEBI:23414,,,,,altered gene expression / gene regulation: silencing,,,YVS,33002079,PubMed,10.1371/journal.ppat.1008919,PLoS Pathog. 2020 Oct 1;16(10):e1008919. doi: 10.1371/journal.ppat.1008919. eCollection 2020 Oct,qianwei666@hotmail.com,"The lesion size after inoculation with the silenced strains was smaller than those after inoculation with the wild-type strain, while the largest lesion size was observed after inoculation with the overexpression strains in the detached leaves of B. napus, T-DNA mutants, overexpression lines and wild-type line of A. thaliana seedlings.",Y Ding 2020,2020,3 genes,Ding-2020-Sclerotinia sclerotiorum utilizes ho,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17529,PHI:11002,UniProt,A7EJT3,GenBank,EDO03099,,,1980,SS1G_05578 (SsCTR1),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),cv. Zhongshuang 11,,,leaf,copper transporter,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; CuSO4,H2O2: CHEBI:16240; CuSO4: CHEBI:23414,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33002079,PubMed,10.1371/journal.ppat.1008919,PLoS Pathog. 2020 Oct 1;16(10):e1008919. doi: 10.1371/journal.ppat.1008919. eCollection 2020 Oct,qianwei666@hotmail.com,"The lesion size after inoculation with the silenced strains was smaller than those after inoculation with the wild-type strain, while the largest lesion size was observed after inoculation with the overexpression strains in the detached leaves of B. napus, T-DNA mutants, overexpression lines and wild-type line of A. thaliana seedlings.",Y Ding 2020,2020,3 genes,Ding-2020-Sclerotinia sclerotiorum utilizes ho,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17530,PHI:11003,UniProt,A7E480,GenBank,EDN90702,,,1980,SS1G_00102 (SsCCS),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),cv. Zhongshuang 11,,,leaf,superoxide dismutase 1 copper chaperone,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; CuSO4,H2O2: CHEBI:16240; CuSO4: CHEBI:23414,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33002079,PubMed,10.1371/journal.ppat.1008919,PLoS Pathog. 2020 Oct 1;16(10):e1008919. doi: 10.1371/journal.ppat.1008919. eCollection 2020 Oct,qianwei666@hotmail.com,"The lesion size after inoculation with the silenced strains was smaller than those after inoculation with the wild-type strain, while the largest lesion size was observed after inoculation with the overexpression strains in the detached leaves of B. napus, T-DNA mutants, overexpression lines and wild-type line of A. thaliana seedlings.",Y Ding 2020,2020,3 genes,Ding-2020-Sclerotinia sclerotiorum utilizes ho,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17531,PHI:11004,UniProt,A7EZX1,GenBank,EDN95013,,,1980,SS1G_10888 (SsATX1),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),cv. Zhongshuang 11,,,leaf,heavy-metal-associated (HMA) domain-containing protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; CuSO4,H2O2: CHEBI:16240; CuSO4: CHEBI:23414,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33002079,PubMed,10.1371/journal.ppat.1008919,PLoS Pathog. 2020 Oct 1;16(10):e1008919. doi: 10.1371/journal.ppat.1008919. eCollection 2020 Oct,qianwei666@hotmail.com,"The lesion size after inoculation with the silenced strains was smaller than those after inoculation with the wild-type strain, while the largest lesion size was observed after inoculation with the overexpression strains in the detached leaves of B. napus, T-DNA mutants, overexpression lines and wild-type line of A. thaliana seedlings.",Y Ding 2020,2020,3 genes,Ding-2020-Sclerotinia sclerotiorum utilizes ho,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17532,PHI:11005,UniProt,P39172,GenBank,AAC74927,,,K-12,znuA,,,,,,,562,Escherichia coli,,C83902,infection,even-toed ungulates,9823,Sus scrofa (related: pig),IPEC-J2 cell line,,,intestinal epithelial cell,Zn(2(+)) ABC transporter periplasmic binding,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,33028391,PubMed,10.1186/s13567-020-00854-1,Vet Res. 2020 Oct 7;51(1):127. doi: 10.1186/s13567-020-00854-1,yzgqzhu@yzu.edu.cn,Deletion of the ZnuACB system genes decreased the adhesion to IPEC-J2 cells under a zinc deficiency medium.,G Quan 2020,2020,3 genes,Quan-2020-Zinc uptake system ZnuACB is essenti,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17533,PHI:11006,UniProt,P39832,GenBank,AAC74929,,,K-12,znuB,,,,,,,562,Escherichia coli,,C83902,infection,even-toed ungulates,9823,Sus scrofa (related: pig),IPEC-J2 cell line,,,intestinal epithelial cell,Zn(2(+)) ABC transporter membrane subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,33028391,PubMed,10.1186/s13567-020-00854-1,Vet Res. 2020 Oct 7;51(1):127. doi: 10.1186/s13567-020-00854-1,yzgqzhu@yzu.edu.cn,Deletion of the ZnuACB system genes decreased the adhesion to IPEC-J2 cells under a zinc deficiency medium.,G Quan 2020,2020,3 genes,Quan-2020-Zinc uptake system ZnuACB is essenti,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17534,PHI:11007,UniProt,P0A9X1,GenBank,AAC74928,,,K-12,znuC,,,,,,,562,Escherichia coli,,C83902,infection,even-toed ungulates,9823,Sus scrofa (related: pig),IPEC-J2 cell line,,,intestinal epithelial cell,Zn(2(+)) ABC transporter ATP binding subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,33028391,PubMed,10.1186/s13567-020-00854-1,Vet Res. 2020 Oct 7;51(1):127. doi: 10.1186/s13567-020-00854-1,yzgqzhu@yzu.edu.cn,Deletion of the ZnuACB system genes decreased the adhesion to IPEC-J2 cells under a zinc deficiency medium.,G Quan 2020,2020,3 genes,Quan-2020-Zinc uptake system ZnuACB is essenti,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17535,PHI:11005,UniProt,P39172,GenBank,AAC74927,,,K-12,znuA,,,,,,PHI:11006; PHI:11007,562,Escherichia coli,,C83902,infection,even-toed ungulates,9823,Sus scrofa (related: pig),IPEC-J2 cell line,,,intestinal epithelial cell,Zn(2(+)) ABC transporter periplasmic binding,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,33028391,PubMed,10.1186/s13567-020-00854-1,Vet Res. 2020 Oct 7;51(1):127. doi: 10.1186/s13567-020-00854-1,yzgqzhu@yzu.edu.cn,Deletion of the ZnuACB system genes decreased the adhesion to IPEC-J2 cells under a zinc deficiency medium.,G Quan 2020,2020,3 genes,Quan-2020-Zinc uptake system ZnuACB is essenti,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17536,PHI:11006,UniProt,P39832,GenBank,AAC74929,,,K-12,znuB,,,,,,PHI:11005; PHI:11007,562,Escherichia coli,,C83902,infection,even-toed ungulates,9823,Sus scrofa (related: pig),IPEC-J2 cell line,,,intestinal epithelial cell,Zn(2(+)) ABC transporter membrane subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,33028391,PubMed,10.1186/s13567-020-00854-1,Vet Res. 2020 Oct 7;51(1):127. doi: 10.1186/s13567-020-00854-1,yzgqzhu@yzu.edu.cn,Deletion of the ZnuACB system genes decreased the adhesion to IPEC-J2 cells under a zinc deficiency medium.,G Quan 2020,2020,3 genes,Quan-2020-Zinc uptake system ZnuACB is essenti,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17537,PHI:11007,UniProt,P0A9X1,GenBank,AAC74928,,,K-12,znuC,,,,,,PHI:11005; PHI:11006,562,Escherichia coli,,C83902,infection,even-toed ungulates,9823,Sus scrofa (related: pig),IPEC-J2 cell line,,,intestinal epithelial cell,Zn(2(+)) ABC transporter ATP binding subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,33028391,PubMed,10.1186/s13567-020-00854-1,Vet Res. 2020 Oct 7;51(1):127. doi: 10.1186/s13567-020-00854-1,yzgqzhu@yzu.edu.cn,Deletion of the ZnuACB system genes decreased the adhesion to IPEC-J2 cells under a zinc deficiency medium.,G Quan 2020,2020,3 genes,Quan-2020-Zinc uptake system ZnuACB is essenti,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17538,PHI:11008,UniProt,A0A0P9KK16,GenBank,KPW29847,,,ICMP3918,rsmA,,,,,,,47877,Pseudomonas amygdali,,pv. phaseolicola strain 1448A,blight (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Canadian Wonder,,,pod; leaf,ribosomal RNA small subunit methyltransferase A,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,33036191,PubMed,10.3390/microorganisms8101536,Microorganisms. 2020 Oct 6;8(10):1536. doi: 10.3390/microorganisms8101536,martamgv@uma.es,"Only double rsmA-rsmE mutants showed significantly altered phenotypes in functional analyses, being impaired for symptom elicitation in bean, including in planta growth, and for induction of the hypersensitive response in tobacco.",D Ramírez-Zapata 2020,2020,3 genes,Ramirez-Zapata-2020-Two Homologues of the Glob,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17539,PHI:11009,UniProt,A0A0P9IW96,GenBank,KPW41506,,,ICMP3918,rsmE,,,,,,,47877,Pseudomonas amygdali,,pv. phaseolicola strain 1448A,blight (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Canadian Wonder,,,pod; leaf,ribosomal RNA small subunit methyltransferase E,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,33036191,PubMed,10.3390/microorganisms8101536,Microorganisms. 2020 Oct 6;8(10):1536. doi: 10.3390/microorganisms8101536,martamgv@uma.es,"Only double rsmA-rsmE mutants showed significantly altered phenotypes in functional analyses, being impaired for symptom elicitation in bean, including in planta growth, and for induction of the hypersensitive response in tobacco.",D Ramírez-Zapata 2020,2020,3 genes,Ramirez-Zapata-2020-Two Homologues of the Glob,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17540,PHI:11008,UniProt,A0A0P9KK16,GenBank,KPW29847,,,ICMP3918,rsmA,,,,,,PHI:11009,47877,Pseudomonas amygdali,,pv. phaseolicola strain 1448A,blight (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Canadian Wonder,,,pod; leaf,ribosomal RNA small subunit methyltransferase A,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,33036191,PubMed,10.3390/microorganisms8101536,Microorganisms. 2020 Oct 6;8(10):1536. doi: 10.3390/microorganisms8101536,martamgv@uma.es,"Only double rsmA-rsmE mutants showed significantly altered phenotypes in functional analyses, being impaired for symptom elicitation in bean, including in planta growth, and for induction of the hypersensitive response in tobacco.",D Ramírez-Zapata 2020,2020,3 genes,Ramirez-Zapata-2020-Two Homologues of the Glob,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17541,PHI:11009,UniProt,A0A0P9IW96,GenBank,KPW41506,,,ICMP3918,rsmE,,,,,,PHI:11008,47877,Pseudomonas amygdali,,pv. phaseolicola strain 1448A,blight (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Canadian Wonder,,,pod; leaf,ribosomal RNA small subunit methyltransferase E,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,33036191,PubMed,10.3390/microorganisms8101536,Microorganisms. 2020 Oct 6;8(10):1536. doi: 10.3390/microorganisms8101536,martamgv@uma.es,"Only double rsmA-rsmE mutants showed significantly altered phenotypes in functional analyses, being impaired for symptom elicitation in bean, including in planta growth, and for induction of the hypersensitive response in tobacco.",D Ramírez-Zapata 2020,2020,3 genes,Ramirez-Zapata-2020-Two Homologues of the Glob,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17542,PHI:11010,UniProt,A7BFX1,GenBank,BAF73629,,,6605,gacA,,,,,,,47877,Pseudomonas amygdali,,pv. phaseolicola strain 1448A,blight (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Canadian Wonder,,,pod; leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33036191,PubMed,10.3390/microorganisms8101536,Microorganisms. 2020 Oct 6;8(10):1536. doi: 10.3390/microorganisms8101536,martamgv@uma.es,"Only double rsmA-rsmE mutants showed significantly altered phenotypes in functional analyses, being impaired for symptom elicitation in bean, including in planta growth, and for induction of the hypersensitive response in tobacco.",D Ramírez-Zapata 2020,2020,3 genes,Ramirez-Zapata-2020-Two Homologues of the Glob,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17543,PHI:11011,,no data found,GenBank,KAF5261274,,,NRRL 39464,OASTL,,,,,,,5507,Fusarium oxysporum,61366,f. sp. cubense TR4,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),cv. Brazil Cavendish,,,root; leaf,O-acetylhomoserine (thiol)-lyase,,,cysteine biosynthesis,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33050283,PubMed,10.3390/biom10101430,Biomolecules. 2020 Oct 9;10(10):1430. doi: 10.3390/biom10101430,tongzheng@itbb.org.cn,Knockout of the OASTL gene did not affect growth of Foc TR4; but resulted in the loss of pathogenicity in banana 'Brazil'.,D Wang 2020,2020,1 gene,Wang-2020-Secretome Analysis of the Banana Fus,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17544,PHI:11012,UniProt,Q4WNY2,GenBank,EAL90052,,,Af293,metH (AFUA_4G07360),chromosome 4,metH_tetOFF,,,,,746128,Aspergillus fumigatus,,ATCC 46645,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,methionine synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,promoter mutation,,,YVS,33051366,PubMed,10.1128/mBio.01985-20,mBio. 2020 Oct 13;11(5):e01985-20. doi: 10.1128/mBio.01985-20,jorge.amichelias@manchester.ac.uk,"In Aspergillus fumigatus the absence of this enzymatic activity triggered a metabolic imbalance that caused a reduction in intracellular ATP, which prevented fungal growth even in the presence of methionine.",J Scott 2020,2020,1 gene,Scott-2020-Targeting Methionine Synthase in a,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17545,PHI:11012,UniProt,Q4WNY2,GenBank,EAL90052,,,Af293,metH (AFUA_4G07360),chromosome 4,metH_tetOFF,,,,,746128,Aspergillus fumigatus,,ATCC 46645,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,methionine synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,promoter mutation,,,YVS,33051366,PubMed,10.1128/mBio.01985-20,mBio. 2020 Oct 13;11(5):e01985-20. doi: 10.1128/mBio.01985-20,jorge.amichelias@manchester.ac.uk,"In Aspergillus fumigatus the absence of this enzymatic activity triggered a metabolic imbalance that caused a reduction in intracellular ATP, which prevented fungal growth even in the presence of methionine.",J Scott 2020,2020,1 gene,Scott-2020-Targeting Methionine Synthase in a,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17546,PHI:11013,UniProt,M4BIN0,,,,,,HaCR1 (HpaG806256),,,,,,,272952,Hyaloperonospora arabidopsidis,,Noco2,downy mildew (Arabidopsis),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,33063828,PubMed,10.1093/jxb/eraa472,J Exp Bot. 2020 Oct 16:eraa472. doi: 10.1093/jxb/eraa472. Online ahead of print,a.weiberg@lmu.de,HaCR1 HIGS resulted in H. arabidopsidis induced local plant cell death and reduced pathogen reproduction.,F Dunker 2020,2020,1 gene,Dunker-2020-An Arabidopsis downy mildew non-Rx,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17547,PHI:11013,UniProt,M4BIN0,,,,,,HaCR1 (HpaG806256),,,,,,,272952,Hyaloperonospora arabidopsidis,,Noco2,downy mildew (Arabidopsis),eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33063828,PubMed,10.1093/jxb/eraa472,J Exp Bot. 2020 Oct 16:eraa472. doi: 10.1093/jxb/eraa472. Online ahead of print,a.weiberg@lmu.de,HaCR1 HIGS resulted in H. arabidopsidis induced local plant cell death and reduced pathogen reproduction.,F Dunker 2020,2020,1 gene,Dunker-2020-An Arabidopsis downy mildew non-Rx,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17548,PHI:11014,UniProt,A0A059ZHI3,GenBank,OBN25288,,,ABUH754,basG,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,histidine decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17549,PHI:11015,,no data found,,,,,,bfnL,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,putative acetyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17550,PHI:11016,,no data found,,,,,,fbsE,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,putative nonribosomal peptide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17551,PHI:11014,UniProt,A0A059ZHI3,GenBank,OBN25288,,,ABUH754,basG,,,,,,PHI:11015,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,histidine decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17552,PHI:11015,,no data found,,,,,,bfnL,,,,,,PHI:11014,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,putative acetyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17553,PHI:11014,UniProt,A0A059ZHI3,GenBank,OBN25288,,,ABUH754,basG,,,,,,PHI:11016,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,histidine decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17554,PHI:11016,,no data found,,,,,,fbsE,,,,,,PHI:11014,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,putative nonribosomal peptide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17555,PHI:11015,,no data found,,,,,,bfnL,,,,,,PHI:11016,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,putative acetyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17556,PHI:11016,,no data found,,,,,,fbsE,,,,,,PHI:11015,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,putative nonribosomal peptide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17557,PHI:11014,UniProt,A0A059ZHI3,GenBank,OBN25288,,,ABUH754,basG,,,,,,PHI:11015; PHI:11016,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,histidine decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17558,PHI:11015,,no data found,,,,,,bfnL,,,,,,PHI:11014; PHI:11016,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,putative acetyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17559,PHI:11016,,no data found,,,,,,fbsE,,,,,,PHI:11014; PHI:11015,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney; heart; liver; spleen; lung; blood,putative nonribosomal peptide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33075115,PubMed,10.1371/journal.ppat.1008995,PLoS Pathog. 2020 Oct 19;16(10):e1008995. doi: 10.1371/journal.ppat.1008995. eCollection 2020 Oct,eric.skaar@vumc.org,Acinetobactin alone was required for the survival and pathogenesis of A. baumannii during bacteremia.,J R Sheldon 2020,2020,3 genes,Sheldon-2020-Acinetobacter baumannii can use m,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17560,PHI:11017,,no data found,,,,,,XLOC_00170 (Av2),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker; cv. Aibou,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33078534,PubMed,10.1111/1462-2920.15288,Environ Microbiol. 2020 Oct 19. doi: 10.1111/1462-2920.15288. Online ahead of print,bart.thomma@wur.nl,The XLOC_00170 deletion strains caused stunting of tomato plants.,E A Chavarro-Carrero 2020,2020,1 gene,Chavarro-Carrer-2020-Comparative genomics reve,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17561,PHI:11017,,no data found,,,,,,XLOC_00170 (Av2),,,,,,,27337,Verticillium dahliae,,TO22,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker; cv. Aibou,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33078534,PubMed,10.1111/1462-2920.15288,Environ Microbiol. 2020 Oct 19. doi: 10.1111/1462-2920.15288. Online ahead of print,bart.thomma@wur.nl,The XLOC_00170 deletion strains caused stunting of tomato plants.,E A Chavarro-Carrero 2020,2020,1 gene,Chavarro-Carrer-2020-Comparative genomics reve,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17562,PHI:11018,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,PHI:11019,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,extracellular signal-regulated kinase 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17563,PHI:11019,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,PHI:11018,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17564,PHI:11018,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,PHI:11020,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,extracellular signal-regulated kinase 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17565,PHI:11020,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,PHI:11018,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17566,PHI:11018,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,PHI:11021,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,extracellular signal-regulated kinase 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17567,PHI:11021,UniProt,Q92207,GenBank,AOW27369,,,SC5314,hog1,chromosome 2,,,,,PHI:11018,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17568,PHI:11021,UniProt,Q92207,GenBank,AOW27369,,,SC5314,hog1,chromosome 2,,,,,PHI:11020,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17569,PHI:11020,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,PHI:11021,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17570,PHI:11019,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,PHI:11021,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17571,PHI:11021,UniProt,Q92207,GenBank,AOW27369,,,SC5314,hog1,chromosome 2,,,,,PHI:11019,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17572,PHI:11019,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,PHI:11020,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,unaffected pathogenicity,,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17573,PHI:11020,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,PHI:11019,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,unaffected pathogenicity,,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17574,PHI:11018,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,PHI:11019; PHI:11020,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,extracellular signal-regulated kinase 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17575,PHI:11019,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,PHI:11018; PHI:11020,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17576,PHI:11020,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,PHI:11018; PHI:11019,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17577,PHI:11018,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,PHI:11020; PHI:11021,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,extracellular signal-regulated kinase 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17578,PHI:11019,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,PHI:11018; PHI:11021,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17579,PHI:11021,UniProt,Q92207,GenBank,AOW27369,,,SC5314,hog1,chromosome 2,,,,,PHI:11018; PHI:11020,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17580,PHI:11020,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,PHI:11018; PHI:11021,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17581,PHI:11021,UniProt,Q92207,GenBank,AOW27369,,,SC5314,hog1,chromosome 2,,,,,PHI:11020; PHI:11019,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17582,PHI:11020,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,PHI:11021; PHI:11019,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17583,PHI:11019,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,PHI:11021; PHI:11020,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17584,PHI:11018,UniProt,Q5A1D3,GenBank,AOW29372,,,SC5314,cek1,chromosome 4,,,,,PHI:11019; PHI:11020; PHI:11021,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,extracellular signal-regulated kinase 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17585,PHI:11019,UniProt,A0A1D8PT38,GenBank,AOW31305,,,SC5314,cek2,chromosome R,,,,,PHI:11018; PHI:11020; PHI:11021,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17586,PHI:11020,UniProt,Q5AAG6,GenBank,AOW30783,,,SC5314,mkc1,chromosome R,,,,,PHI:11018; PHI:11019; PHI:11021,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17587,PHI:11021,UniProt,Q92207,GenBank,AOW27369,,,SC5314,hog1,chromosome 2,,,,,PHI:11018; PHI:11019; PHI:11020,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl; sorbitol; H2O2; menadione; Congo red; amphotericin B; fluconazole; nikkomycin Z,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; nikkomycin Z: CHEBI:623918,,,,,gene deletion: full,,,YVS,33080787,PubMed,10.3390/jof6040230,J Fungi (Basel). 2020 Oct 17;6(4):E230. doi: 10.3390/jof6040230,inescorreia@ua.pt,"An increased susceptibility of all triple mutants compared to the strains defective in only two kinases and, in turn, an increased susceptibility for the quadruple mutant as compared to the triple deletion mutants was observed.",I Correia 2020,2020,4 genes,Correia-2020-Characterization of a Candida alb,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17588,PHI:11022,UniProt,J9VLD1,GenBank,AFR95292,,,H99,pho81 (CNAG_02541),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,cyclin-dependent protein kinase inhibitor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33082258,PubMed,10.1128/mBio.01920-20,mBio. 2020 Oct 20;11(5):e01920-20. doi: 10.1128/mBio.01920-20,julianne.djordjevic@sydney.edu.au,"Blocking IP7-Pho81 interaction using site-directed mutagenesis led to a dramatic loss of fungal virulence in a mouse infection model, and the effect was similar to that observed following PHO81 gene deletion.",D Desmarini 2020,2020,1 gene,Desmarini-2020-IP(7)-SPX Domain Interaction Co,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17589,PHI:11022,UniProt,J9VLD1,GenBank,AFR95292,,,H99,pho81 (CNAG_02541),chromosome 6,"K221,224,228 in the cryptococcal Pho81 SPX domain was altered to alanine, creating the Pho81 SPXAAA strain",,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,cyclin-dependent protein kinase inhibitor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation: characterised; gene complementation,,,YVS,33082258,PubMed,10.1128/mBio.01920-20,mBio. 2020 Oct 20;11(5):e01920-20. doi: 10.1128/mBio.01920-20,julianne.djordjevic@sydney.edu.au,"Blocking IP7-Pho81 interaction using site-directed mutagenesis led to a dramatic loss of fungal virulence in a mouse infection model, and the effect was similar to that observed following PHO81 gene deletion.",D Desmarini 2020,2020,1 gene,Desmarini-2020-IP(7)-SPX Domain Interaction Co,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17590,PHI:11023,UniProt,A3N3P9,GenBank,ABN75035,,,L20,hfq,,,,,,,715,Actinobacillus pleuropneumoniae,,Shope 4074,pleuropneumonia (pig),moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RNA chaperone,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; ethanol; H2O2,NaCl: CHEBI:26710; ethanol: CHEBI:16236; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33095236,PubMed,10.1093/femspd/ftaa066,Pathog Dis. 2020 Nov 23;78(9):ftaa066. doi: 10.1093/femspd/ftaa066,dbazzolli@ufv.br,"Differences were seen between the three serovar WT strains regarding adherence, stress response and virulence in G. mellonella, and deletion of hfq affected some, but not all of these phenotypes, depending on serovar.",J S Crispim 2020,2020,1 gene,Crispim-2020-Serovar-dependent differences in,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17591,PHI:11023,UniProt,A3N3P9,GenBank,ABN75035,,,L20,hfq,,,,,,,715,Actinobacillus pleuropneumoniae,,MIDG2331,pleuropneumonia (pig),moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RNA chaperone,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; ethanol; H2O2,NaCl: CHEBI:26710; ethanol: CHEBI:16236; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33095236,PubMed,10.1093/femspd/ftaa066,Pathog Dis. 2020 Nov 23;78(9):ftaa066. doi: 10.1093/femspd/ftaa066,dbazzolli@ufv.br,"Differences were seen between the three serovar WT strains regarding adherence, stress response and virulence in G. mellonella, and deletion of hfq affected some, but not all of these phenotypes, depending on serovar.",J S Crispim 2020,2020,1 gene,Crispim-2020-Serovar-dependent differences in,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17592,PHI:11023,UniProt,A3N3P9,GenBank,ABN75035,,,L20,hfq,,,,,,,715,Actinobacillus pleuropneumoniae,,HS143,pleuropneumonia (pig),moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RNA chaperone,,,,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl; ethanol; H2O2,NaCl: CHEBI:26710; ethanol: CHEBI:16236; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33095236,PubMed,10.1093/femspd/ftaa066,Pathog Dis. 2020 Nov 23;78(9):ftaa066. doi: 10.1093/femspd/ftaa066,dbazzolli@ufv.br,"Differences were seen between the three serovar WT strains regarding adherence, stress response and virulence in G. mellonella, and deletion of hfq affected some, but not all of these phenotypes, depending on serovar.",J S Crispim 2020,2020,1 gene,Crispim-2020-Serovar-dependent differences in,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17593,PHI:11023,UniProt,A3N3P9,GenBank,ABN75035,,,L20,hfq,,,,,,,715,Actinobacillus pleuropneumoniae,,Shope 4074,pleuropneumonia (pig),primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,RNA chaperone,,,,reduced virulence,,,,,,,,reduced,,no,NaCl; ethanol; H2O2,NaCl: CHEBI:26710; ethanol: CHEBI:16236; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33095236,PubMed,10.1093/femspd/ftaa066,Pathog Dis. 2020 Nov 23;78(9):ftaa066. doi: 10.1093/femspd/ftaa066,dbazzolli@ufv.br,"Differences were seen between the three serovar WT strains regarding adherence, stress response and virulence in G. mellonella, and deletion of hfq affected some, but not all of these phenotypes, depending on serovar.",J S Crispim 2020,2020,1 gene,Crispim-2020-Serovar-dependent differences in,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17594,PHI:11023,UniProt,A3N3P9,GenBank,ABN75035,,,L20,hfq,,,,,,,715,Actinobacillus pleuropneumoniae,,MIDG2331,pleuropneumonia (pig),primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,RNA chaperone,,,,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl; ethanol; H2O2,NaCl: CHEBI:26710; ethanol: CHEBI:16236; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33095236,PubMed,10.1093/femspd/ftaa066,Pathog Dis. 2020 Nov 23;78(9):ftaa066. doi: 10.1093/femspd/ftaa066,dbazzolli@ufv.br,"Differences were seen between the three serovar WT strains regarding adherence, stress response and virulence in G. mellonella, and deletion of hfq affected some, but not all of these phenotypes, depending on serovar.",J S Crispim 2020,2020,1 gene,Crispim-2020-Serovar-dependent differences in,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17595,PHI:11023,UniProt,A3N3P9,GenBank,ABN75035,,,L20,hfq,,,,,,,715,Actinobacillus pleuropneumoniae,,HS143,pleuropneumonia (pig),primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,RNA chaperone,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; ethanol; H2O2,NaCl: CHEBI:26710; ethanol: CHEBI:16236; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33095236,PubMed,10.1093/femspd/ftaa066,Pathog Dis. 2020 Nov 23;78(9):ftaa066. doi: 10.1093/femspd/ftaa066,dbazzolli@ufv.br,"Differences were seen between the three serovar WT strains regarding adherence, stress response and virulence in G. mellonella, and deletion of hfq affected some, but not all of these phenotypes, depending on serovar.",J S Crispim 2020,2020,1 gene,Crispim-2020-Serovar-dependent differences in,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17596,PHI:11024,,no data found,GenBank,WP_183143638,,,,msaA,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,blood; heart; spleen; bone,regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33109085,PubMed,10.1186/s12866-020-01964-8,BMC Microbiol. 2020 Oct 27;20(1):324. doi: 10.1186/s12866-020-01964-8,gyan.sahukhal@usm.edu,"Deletion of msaABCR operon in USA300 LAC strain lead to defective biofilm in K-wire implants, decreased intraosseous survival, and reduced cortical bone destruction.",G S Sahukhal 2020,2020,4 genes,Sahukhal-2020-The role of the msaABCR operon i,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17597,PHI:11025,,no data found,GenBank,WP_185611015,,,,msaB,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,blood; heart; spleen; bone,cold shock protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33109085,PubMed,10.1186/s12866-020-01964-8,BMC Microbiol. 2020 Oct 27;20(1):324. doi: 10.1186/s12866-020-01964-8,gyan.sahukhal@usm.edu,"Deletion of msaABCR operon in USA300 LAC strain lead to defective biofilm in K-wire implants, decreased intraosseous survival, and reduced cortical bone destruction.",G S Sahukhal 2020,2020,4 genes,Sahukhal-2020-The role of the msaABCR operon i,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17598,PHI:11026,,no data found,GenBank,WP_191135765,,,,msaC,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,blood; heart; spleen; bone,SarA expression modulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33109085,PubMed,10.1186/s12866-020-01964-8,BMC Microbiol. 2020 Oct 27;20(1):324. doi: 10.1186/s12866-020-01964-8,gyan.sahukhal@usm.edu,"Deletion of msaABCR operon in USA300 LAC strain lead to defective biofilm in K-wire implants, decreased intraosseous survival, and reduced cortical bone destruction.",G S Sahukhal 2020,2020,4 genes,Sahukhal-2020-The role of the msaABCR operon i,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17599,PHI:11027,,no data found,,,,,,msaR,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,blood; heart; spleen; bone,uncharacterised protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33109085,PubMed,10.1186/s12866-020-01964-8,BMC Microbiol. 2020 Oct 27;20(1):324. doi: 10.1186/s12866-020-01964-8,gyan.sahukhal@usm.edu,"Deletion of msaABCR operon in USA300 LAC strain lead to defective biofilm in K-wire implants, decreased intraosseous survival, and reduced cortical bone destruction.",G S Sahukhal 2020,2020,4 genes,Sahukhal-2020-The role of the msaABCR operon i,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17600,PHI:11024,,no data found,GenBank,WP_183143638,,,,msaA,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,liver; lung; kidney,regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33109085,PubMed,10.1186/s12866-020-01964-8,BMC Microbiol. 2020 Oct 27;20(1):324. doi: 10.1186/s12866-020-01964-8,gyan.sahukhal@usm.edu,"Deletion of msaABCR operon in USA300 LAC strain lead to defective biofilm in K-wire implants, decreased intraosseous survival, and reduced cortical bone destruction.",G S Sahukhal 2020,2020,4 genes,Sahukhal-2020-The role of the msaABCR operon i,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17601,PHI:11025,,no data found,GenBank,WP_185611015,,,,msaB,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,liver; lung; kidney,cold shock protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33109085,PubMed,10.1186/s12866-020-01964-8,BMC Microbiol. 2020 Oct 27;20(1):324. doi: 10.1186/s12866-020-01964-8,gyan.sahukhal@usm.edu,"Deletion of msaABCR operon in USA300 LAC strain lead to defective biofilm in K-wire implants, decreased intraosseous survival, and reduced cortical bone destruction.",G S Sahukhal 2020,2020,4 genes,Sahukhal-2020-The role of the msaABCR operon i,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17602,PHI:11026,,no data found,GenBank,WP_191135765,,,,msaC,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,liver; lung; kidney,SarA expression modulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33109085,PubMed,10.1186/s12866-020-01964-8,BMC Microbiol. 2020 Oct 27;20(1):324. doi: 10.1186/s12866-020-01964-8,gyan.sahukhal@usm.edu,"Deletion of msaABCR operon in USA300 LAC strain lead to defective biofilm in K-wire implants, decreased intraosseous survival, and reduced cortical bone destruction.",G S Sahukhal 2020,2020,4 genes,Sahukhal-2020-The role of the msaABCR operon i,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17603,PHI:11027,,no data found,,,,,,msaR,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,liver; lung; kidney,uncharacterised protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33109085,PubMed,10.1186/s12866-020-01964-8,BMC Microbiol. 2020 Oct 27;20(1):324. doi: 10.1186/s12866-020-01964-8,gyan.sahukhal@usm.edu,"Deletion of msaABCR operon in USA300 LAC strain lead to defective biofilm in K-wire implants, decreased intraosseous survival, and reduced cortical bone destruction.",G S Sahukhal 2020,2020,4 genes,Sahukhal-2020-The role of the msaABCR operon i,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17604,PHI:11028,UniProt,A0A1D8PG88,GenBank,KHC88649,,,SC5314,rsc4,,,,,,,5476,Candida albicans,,SGC2024,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,chromatin structure remodeling complex protein,,,,reduced virulence,,,,,,,,,,no,H2O2; KCl; NaCl; DMSO; ethanol; calcofluor white; SDS,H2O2: CHEBI:16240; KCl: CHEBI:32588; NaCl: CHEBI:26710; DMSO: CHEBI:28262; ethanol: CHEBI:16236; calcofluor white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,33151931,PubMed,10.1371/journal.pgen.1009071,PLoS Genet. 2020 Nov 5;16(11):e1009071. doi: 10.1371/journal.pgen.1009071. eCollection 2020 Nov,santanughosh@iitb.ac.in,Rsc4 was required for full virulence of C. albicans in the murine model of systemic infection.,V K Balachandra 2020,2020,1 gene,Balachandra-2020-The RSC (Remodels the Structu,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17605,PHI:11028,UniProt,A0A1D8PG88,GenBank,KHC88649,,,SC5314,rsc4,,,,,,,5476,Candida albicans,,SGC2024,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bone marrow-derived macrophage,chromatin structure remodeling complex protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; KCl; NaCl; DMSO; ethanol; calcofluor white; SDS,H2O2: CHEBI:16240; KCl: CHEBI:32588; NaCl: CHEBI:26710; DMSO: CHEBI:28262; ethanol: CHEBI:16236; calcofluor white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,33151931,PubMed,10.1371/journal.pgen.1009071,PLoS Genet. 2020 Nov 5;16(11):e1009071. doi: 10.1371/journal.pgen.1009071. eCollection 2020 Nov,santanughosh@iitb.ac.in,Rsc4 was required for full virulence of C. albicans in the murine model of systemic infection.,V K Balachandra 2020,2020,1 gene,Balachandra-2020-The RSC (Remodels the Structu,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17606,PHI:11028,UniProt,A0A1D8PG88,GenBank,KHC88649,,,SC5314,rsc4,,,,,,,5476,Candida albicans,,SGC2024,invasive candidiasis,primates,9606,Homo sapiens (related: human),,,,neutrophil,chromatin structure remodeling complex protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; KCl; NaCl; DMSO; ethanol; calcofluor white; SDS,H2O2: CHEBI:16240; KCl: CHEBI:32588; NaCl: CHEBI:26710; DMSO: CHEBI:28262; ethanol: CHEBI:16236; calcofluor white: CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,33151931,PubMed,10.1371/journal.pgen.1009071,PLoS Genet. 2020 Nov 5;16(11):e1009071. doi: 10.1371/journal.pgen.1009071. eCollection 2020 Nov,santanughosh@iitb.ac.in,Rsc4 was required for full virulence of C. albicans in the murine model of systemic infection.,V K Balachandra 2020,2020,1 gene,Balachandra-2020-The RSC (Remodels the Structu,BATCH_103C,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17607,PHI:11029,UniProt,Q4WG62,GenBank,EAL87079,,,Af293,nsdC (Afu7g03910),chromosome 7,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,C2H2-type zinc finger transcription factor,,,,reduced virulence,yes,,,,,reduced,,reduced,,no,sorbitol; nikkomycin Z; Congo red (CR); calcofluor white (CFW); caspofungin; calcium chloride (CaCl2); cyclosporine,sorbitol: CHEBI:30911; nikkomycin Z: CHEBI:623918; Congo red (CR): CHEBI:34653; calcofluor white (CFW): CHEBI:50011; caspofungin: CHEBI:474180; calcium chloride (CaCl2): CHEBI:3312; cyclosporine: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,33402536,PubMed,10.1128/mBio.03102-20,mBio. 2021 Jan 5;12(1):e03102-20,ggoldman@usp.br,"NsdC was found to be essential for sexual development, with deletion of the nsdC gene in both MAT1-1 and MAT1-2 mating partners of a cross leading to complete loss of fertility.",P Alves de Castro 2021,2021,1 gene,Alves de Castro-2021-Novel Biological Function,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17608,PHI:11029,UniProt,Q4WG62,GenBank,EAL87079,,,Af293,nsdC (Afu7g03910),chromosome 7,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; bone marrow-derived macrophage,C2H2-type zinc finger transcription factor,,,,reduced virulence,yes,,,,,reduced,,reduced,,no,sorbitol; nikkomycin Z; Congo red (CR); calcofluor white (CFW); caspofungin; calcium chloride (CaCl2); cyclosporine,sorbitol: CHEBI:30911; nikkomycin Z: CHEBI:623918; Congo red (CR): CHEBI:34653; calcofluor white (CFW): CHEBI:50011; caspofungin: CHEBI:474180; calcium chloride (CaCl2): CHEBI:3312; cyclosporine: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,33402536,PubMed,10.1128/mBio.03102-20,mBio. 2021 Jan 5;12(1):e03102-20,ggoldman@usp.br,"NsdC was found to be essential for sexual development, with deletion of the nsdC gene in both MAT1-1 and MAT1-2 mating partners of a cross leading to complete loss of fertility.",P Alves de Castro 2021,2021,1 gene,Alves de Castro-2021-Novel Biological Function,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17609,PHI:11030,UniProt,A0A380PIP1,GenBank,CAL18716,,,CO92,bipA,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,putative GTPase,,,,reduced virulence,,,,,,,,,,no,polymyxin B; LL-37,polymyxin B: CHEBI:8309; LL-37: CHEBI:81664,,,,,gene deletion: full; gene complementation,,,YVS,33257531,PubMed,10.1128/IAI.00673-20,Infect Immun. 2021 Jan 19;89(2):e00673-20,RDPechous@uams.edu,BipA is a Y. pestis virulence factor that promoted defense against early neutrophil-mediated bacterial killing in the lung.,S D Crane 2021,2021,1 gene,Crane-2021-The Yersinia pestis GTPase BipA Pro,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17610,PHI:11030,UniProt,A0A380PIP1,GenBank,CAL18716,,,CO92,bipA,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),MH-S cell line,,,alveolar macrophage,putative GTPase,,,,reduced virulence,,,,,,,,,,no,polymyxin B; LL-37,polymyxin B: CHEBI:8309; LL-37: CHEBI:81664,,,,,gene deletion: full; gene complementation,,,YVS,33257531,PubMed,10.1128/IAI.00673-20,Infect Immun. 2021 Jan 19;89(2):e00673-20,RDPechous@uams.edu,BipA is a Y. pestis virulence factor that promoted defense against early neutrophil-mediated bacterial killing in the lung.,S D Crane 2021,2021,1 gene,Crane-2021-The Yersinia pestis GTPase BipA Pro,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17611,PHI:11030,UniProt,A0A380PIP1,GenBank,CAL18716,,,CO92,bipA,,,,,,,632,Yersinia pestis,214092,CO92,pneumonic plague,primates,9606,Homo sapiens (related: human),,,,neutrophil; alveolar macrophage,putative GTPase,,,,reduced virulence,,,,,,,,,,no,polymyxin B; LL-37,polymyxin B: CHEBI:8309; LL-37: CHEBI:81664,,,,,gene deletion: full; gene complementation,,,YVS,33257531,PubMed,10.1128/IAI.00673-20,Infect Immun. 2021 Jan 19;89(2):e00673-20,RDPechous@uams.edu,BipA is a Y. pestis virulence factor that promoted defense against early neutrophil-mediated bacterial killing in the lung.,S D Crane 2021,2021,1 gene,Crane-2021-The Yersinia pestis GTPase BipA Pro,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17612,PHI:11031,UniProt,Q9KVR9,GenBank,AAF93248,,,N16961,tsrA (VC0070),chromosome I,,,,,,666,Vibrio cholerae,,El Tor C6706,diarrhea; cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33298574,PubMed,10.1128/mSphere.01014-20,mSphere. 2020 Dec 9;5(6):e01014-20,bwdavies@utexas.edu,"Deletion of tsrA completely compensated for the attenuation observed when ToxR, an essential virulence gene regulator, was also deleted in an infant mouse intestinal model.",C D DuPai 2020,2020,3 genes,DuPai-2020-TsrA Regulates Virulence and Intest,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17613,PHI:11031,UniProt,Q9KVR9,GenBank,AAF93248,,,N16961,tsrA (VC0070),chromosome I,,,,,PHI:11032; PHI:11033,666,Vibrio cholerae,,El Tor C6706,diarrhea; cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33298574,PubMed,10.1128/mSphere.01014-20,mSphere. 2020 Dec 9;5(6):e01014-20,bwdavies@utexas.edu,"Deletion of tsrA completely compensated for the attenuation observed when ToxR, an essential virulence gene regulator, was also deleted in an infant mouse intestinal model.",C D DuPai 2020,2020,3 genes,DuPai-2020-TsrA Regulates Virulence and Intest,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17614,PHI:11032,UniProt,P15795,GenBank,AAF94145,,,N16961,toxR,chromosome I,,,,,PHI:11031; PHI:11033,666,Vibrio cholerae,,El Tor C6706,diarrhea; cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,Cholera toxin transcriptional activator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33298574,PubMed,10.1128/mSphere.01014-20,mSphere. 2020 Dec 9;5(6):e01014-20,bwdavies@utexas.edu,"Deletion of tsrA completely compensated for the attenuation observed when ToxR, an essential virulence gene regulator, was also deleted in an infant mouse intestinal model.",C D DuPai 2020,2020,3 genes,DuPai-2020-TsrA Regulates Virulence and Intest,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17615,PHI:11033,UniProt,P24003,GenBank,AAF94144,,,N16961,toxS,chromosome I,,,,,PHI:11031; PHI:11032,666,Vibrio cholerae,,El Tor C6706,diarrhea; cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,transmembrane regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33298574,PubMed,10.1128/mSphere.01014-20,mSphere. 2020 Dec 9;5(6):e01014-20,bwdavies@utexas.edu,"Deletion of tsrA completely compensated for the attenuation observed when ToxR, an essential virulence gene regulator, was also deleted in an infant mouse intestinal model.",C D DuPai 2020,2020,3 genes,DuPai-2020-TsrA Regulates Virulence and Intest,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17616,PHI:11032,UniProt,P15795,GenBank,AAF94145,,,N16961,toxR,chromosome I,,,,,PHI:11033,666,Vibrio cholerae,,El Tor C6706,diarrhea; cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,Cholera toxin transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33298574,PubMed,10.1128/mSphere.01014-20,mSphere. 2020 Dec 9;5(6):e01014-20,bwdavies@utexas.edu,"Deletion of tsrA completely compensated for the attenuation observed when ToxR, an essential virulence gene regulator, was also deleted in an infant mouse intestinal model.",C D DuPai 2020,2020,3 genes,DuPai-2020-TsrA Regulates Virulence and Intest,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17617,PHI:11033,UniProt,P24003,GenBank,AAF94144,,,N16961,toxS,chromosome I,,,,,PHI:11032,666,Vibrio cholerae,,El Tor C6706,diarrhea; cholera,rodents,10090,Mus musculus (related: house mouse),,,,intestine,transmembrane regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33298574,PubMed,10.1128/mSphere.01014-20,mSphere. 2020 Dec 9;5(6):e01014-20,bwdavies@utexas.edu,"Deletion of tsrA completely compensated for the attenuation observed when ToxR, an essential virulence gene regulator, was also deleted in an infant mouse intestinal model.",C D DuPai 2020,2020,3 genes,DuPai-2020-TsrA Regulates Virulence and Intest,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17618,PHI:11034,,no data found,,,,,,Vm-milR37,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,microRNA-like RNA,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33278058,PubMed,10.1111/mpp.13023,Mol Plant Pathol. 2021 Feb;22(2):243-254,huanglili@nwsuaf.edu.cn,Apple leaves inoculated with Vm-milR37 overexpression transformants and VmGP deletion mutant displayed increased accumulation of reactive oxygen species compared with the wild type.,H Feng 2021,2021,2 genes,Feng-2021-Vm-milR37 contributes to pathogenici,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17619,PHI:11035,UniProt,A0A194W5S8,GenBank,KUI71622,,,03-8,VmGP (VM1G_06866),chromosome 7,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,glutathione peroxidase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33278058,PubMed,10.1111/mpp.13023,Mol Plant Pathol. 2021 Feb;22(2):243-254,huanglili@nwsuaf.edu.cn,Apple leaves inoculated with Vm-milR37 overexpression transformants and VmGP deletion mutant displayed increased accumulation of reactive oxygen species compared with the wild type.,H Feng 2021,2021,2 genes,Feng-2021-Vm-milR37 contributes to pathogenici,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17620,PHI:11036,,no data found,,,,,,LaeA,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,global regulator for secondary metabolism,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17621,PHI:11036,,no data found,,,,,,LaeA,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,leaf,global regulator for secondary metabolism,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17622,PHI:11037,UniProt,A0A194VTS2,GenBank,KUI67392,,,03-8,NRPS14 (VM1G_03342),chromosome 3,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,"acyl-CoA synthetase family member 2, mitochondrial",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17623,PHI:11037,UniProt,A0A194VTS2,GenBank,KUI67392,,,03-8,NRPS14 (VM1G_03342),chromosome 3,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,leaf,"acyl-CoA synthetase family member 2, mitochondrial",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17624,PHI:11038,UniProt,A0A194VUA1,GenBank,KUI67498,,,03-8,PKS11 (VM1G_03093),chromosome 3,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,conidial yellow pigment biosynthesis polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17625,PHI:11039,UniProt,A0A194VXQ8,GenBank,KUI69031,,,03-8,PKS16 (VM1G_03769),chromosome 4,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,conidial yellow pigment biosynthesis polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17626,PHI:11040,UniProt,A0A194VYT4,GenBank,KUI69406,,,03-8,PKS23 (VM1G_05383),chromosome 5,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,conidial yellow pigment biosynthesis polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17627,PHI:11041,UniProt,A0A194W5I0,GenBank,KUI71338,,,03-8,PKS31 (VM1G_07355),chromosome 7,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,conidial yellow pigment biosynthesis polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17628,PHI:11042,UniProt,A0A194WAB9,GenBank,KUI73389,,,03-8,PKS39 (VM1G_09018),chromosome 10,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,lovastatin diketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17629,PHI:11037,UniProt,A0A194VTS2,GenBank,KUI67392,,,03-8,NRPS14 (VM1G_03342),chromosome 3,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,"acyl-CoA synthetase family member 2, mitochondrial",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17630,PHI:11038,UniProt,A0A194VUA1,GenBank,KUI67498,,,03-8,PKS11 (VM1G_03093),chromosome 3,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,conidial yellow pigment biosynthesis polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17631,PHI:11039,UniProt,A0A194VXQ8,GenBank,KUI69031,,,03-8,PKS16 (VM1G_03769),chromosome 4,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,conidial yellow pigment biosynthesis polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17632,PHI:11040,UniProt,A0A194VYT4,GenBank,KUI69406,,,03-8,PKS23 (VM1G_05383),chromosome 5,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,conidial yellow pigment biosynthesis polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17633,PHI:11041,UniProt,A0A194W5I0,GenBank,KUI71338,,,03-8,PKS31 (VM1G_07355),chromosome 7,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,conidial yellow pigment biosynthesis polyketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17634,PHI:11042,UniProt,A0A194WAB9,GenBank,KUI73389,,,03-8,PKS39 (VM1G_09018),chromosome 10,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,lovastatin diketide synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33250871,PubMed,10.3389/fmicb.2020.581203,Front Microbiol. 2020 Nov 5;11:581203,huanglili@nwsuaf.edu.cn,Deletion of VmLaeA led to greatly reduced virulence with lesion length reduced by 48% on apple twigs.,Y Feng 2020,2020,7 genes,Feng-2020-LaeA Controls Virulence and Secondar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17635,PHI:11043,UniProt,Q9HUS5,GenBank,AE004902_1,,,PAO1,DesB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung; liver; spleen,aerobic desaturase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32323095,PubMed,10.1007/s10123-020-00130-4,Int Microbiol. 2020 Nov;23(4):549-555,kheechoi@wonkwang.ac.kr,More pro-inflammatory cytokines and chemokines were present in desB mutant.,J Ha 2020,2020,1 gene,Ha-2020-The role of Pseudomonas aeruginosa Des,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17636,PHI:11043,UniProt,Q9HUS5,GenBank,AE004902_1,,,PAO1,DesB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,aerobic desaturase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32323095,PubMed,10.1007/s10123-020-00130-4,Int Microbiol. 2020 Nov;23(4):549-555,kheechoi@wonkwang.ac.kr,DesB mutants exhibited lower cytotoxicity in A549 cells.,J Ha 2020,2020,1 gene,Ha-2020-The role of Pseudomonas aeruginosa Des,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17637,PHI:11044,UniProt,Q59VG6,GenBank,AAC99343,,,B311,erg3,chromosome 1,,,,,,5476,Candida albicans,,CAF2,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),DBA/2J,,,liver; kidney; cecum; colon; blood,"sterol C5,6-desaturase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33396406,PubMed,10.3390/pathogens10010023,Pathogens. 2020 Dec 31;10(1):23,taiga-m@nagasaki-u.ac.jp,"The mutant strain showed reduced colonization, pathogenesis, damage to gut mucosa, and chemokine production in the mouse model of invasive candidiasis.",T Hirayama 2020,2020,1 gene,"Hirayama-2020-ERG3-Encoding Sterol C5,6-DESATU",BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17638,PHI:11045,UniProt,A0A4Q9WE38,GenBank,TBW73569,,,E7,srtA,,,,,,,28035,Staphylococcus lugdunensis,,Sl44,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,sortase A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33322541,PubMed,10.3390/microorganisms8121975,Microorganisms. 2020 Dec 11;8(12):1975,karsten.becker@med.uni-greifswald.de,"No decreased adherence and invasion was found in human cell lines, probably caused by the upregulation of further adhesins in DsrtA mutant strains.",M Hussain 2020,2020,1 gene,Hussain-2020-Role of SrtA in Pathogenicity of,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17639,PHI:11045,UniProt,A0A4Q9WE38,GenBank,TBW73569,,,E7,srtA,,,,,,,28035,Staphylococcus lugdunensis,,Sl44,infective endocarditis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,sortase A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33322541,PubMed,10.3390/microorganisms8121975,Microorganisms. 2020 Dec 11;8(12):1975,karsten.becker@med.uni-greifswald.de,"No decreased adherence and invasion was found in human cell lines, probably caused by the upregulation of further adhesins in DsrtA mutant strains.",M Hussain 2020,2020,1 gene,Hussain-2020-Role of SrtA in Pathogenicity of,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17640,PHI:11045,UniProt,A0A4Q9WE38,GenBank,TBW73569,,,E7,srtA,,,,,,,28035,Staphylococcus lugdunensis,,Sl44,infective endocarditis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder carcinoma cell line,sortase A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33322541,PubMed,10.3390/microorganisms8121975,Microorganisms. 2020 Dec 11;8(12):1975,karsten.becker@med.uni-greifswald.de,"No decreased adherence and invasion was found in human cell lines, probably caused by the upregulation of further adhesins in DsrtA mutant strains.",M Hussain 2020,2020,1 gene,Hussain-2020-Role of SrtA in Pathogenicity of,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17641,PHI:11045,UniProt,A0A4Q9WE38,GenBank,TBW73569,,,E7,srtA,,,,,,,28035,Staphylococcus lugdunensis,,Sl48,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,sortase A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33322541,PubMed,10.3390/microorganisms8121975,Microorganisms. 2020 Dec 11;8(12):1975,karsten.becker@med.uni-greifswald.de,"No decreased adherence and invasion was found in human cell lines, probably caused by the upregulation of further adhesins in DsrtA mutant strains.",M Hussain 2020,2020,1 gene,Hussain-2020-Role of SrtA in Pathogenicity of,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17642,PHI:11045,UniProt,A0A4Q9WE38,GenBank,TBW73569,,,E7,srtA,,,,,,,28035,Staphylococcus lugdunensis,,Sl48,infective endocarditis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,sortase A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33322541,PubMed,10.3390/microorganisms8121975,Microorganisms. 2020 Dec 11;8(12):1975,karsten.becker@med.uni-greifswald.de,"No decreased adherence and invasion was found in human cell lines, probably caused by the upregulation of further adhesins in DsrtA mutant strains.",M Hussain 2020,2020,1 gene,Hussain-2020-Role of SrtA in Pathogenicity of,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17643,PHI:11045,UniProt,A0A4Q9WE38,GenBank,TBW73569,,,E7,srtA,,,,,,,28035,Staphylococcus lugdunensis,,Sl48,infective endocarditis,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder carcinoma cell line,sortase A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33322541,PubMed,10.3390/microorganisms8121975,Microorganisms. 2020 Dec 11;8(12):1975,karsten.becker@med.uni-greifswald.de,"No decreased adherence and invasion was found in human cell lines, probably caused by the upregulation of further adhesins in DsrtA mutant strains.",M Hussain 2020,2020,1 gene,Hussain-2020-Role of SrtA in Pathogenicity of,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17644,PHI:11046,UniProt,A8ULG6,GenBank,ACN73235,,,EHE-NE3,netB,,,,,,,1502,Clostridium perfringens,,CNEOP004,intestinal disease,birds,9031,Gallus gallus (related: chicken),Hy-line,,,duodenum; jejunum; cecum,necrotic enteritis toxin B-like,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,33342969,PubMed,10.1292/jvms.20-0623,J Vet Med Sci. 2020 Dec 18,mukamoto@vet.osakafu-u.ac.jp,In vivo pathogenicity of NetB to chicks produced characteristic lesions of necrotic enteritis.,A A Islam 2020,2020,1 gene,Islam-2020-The cytotoxicity and molecular mech,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17645,PHI:11047,,no data found,,,,,,mss2,,,,,,,5476,Candida albicans,237561,SC5314,oral candidiasis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,uncharacterised protein,,,,reduced virulence,,,,,,,,reduced,,no,SDS; calcofluor white; caspofungin,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,33427576,PubMed,10.1080/21505594.2020.1870082,Virulence. 2021 Dec;12(1):281-297,chinghsuanlin@ntu.edu.tw,The MSS2 deletion strains could not form robust biofilms and exhibited significantly reduced virulence.,C L Ke 2021,2021,1 gene,Ke-2021-MSS2 maintains mitochondrial function,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17646,PHI:11047,,no data found,,,,,,mss2,,,,,,,5476,Candida albicans,237561,SC5314,oral candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney; spleen,uncharacterised protein,,,,reduced virulence,,,,,,,,reduced,,no,SDS; calcofluor white; caspofungin,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,33427576,PubMed,10.1080/21505594.2020.1870082,Virulence. 2021 Dec;12(1):281-297,chinghsuanlin@ntu.edu.tw,The MSS2 deletion strains could not form robust biofilms and exhibited significantly reduced virulence.,C L Ke 2021,2021,1 gene,Ke-2021-MSS2 maintains mitochondrial function,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17647,PHI:11048,UniProt,A0A1C3YK53,GenBank,SCB64914,,,PH-1,FgVPS74 (FGSG_06346),chromosome 3,,,,,,5518,Fusarium graminearum,,Z-3643,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,uncharacterised protein,,,trichothecene biosynthesis,reduced virulence,,,,,,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25845538,PubMed,10.1007/s12275-015-5067-7,J Microbiol. 2015 Apr;53(4):243-9,sy14@sch.ac.kr,"FgVPS74 was involved in hyphal growth, conidiation, sexual development, mycotoxin production, and virulence towards host plants in F. graminearum.",H K Kim 2015,2015,1 gene,Kim-2015-Multiple roles of a putative vacuolar,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17648,PHI:11049,,no data found,,,,,,RaoN,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain UK1,colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,NaNO2; S-nitrosoglutathione,NaNO2: CHEBI:78870; S-nitrosoglutathione: CHEBI:50091,,,,,gene deletion: full; gene complementation,,,YVS,32279276,PubMed,10.1007/s12275-020-0027-2,J Microbiol. 2020 Jun;58(6):499-506,yhlee@dongseo.ac.kr,"Inactivation of raoN leads to an increase in the intracellular level of reactive oxygen species (ROS) in Salmonella-infected macrophages, suggesting that RaoN is involved in the inhibition of NADPH oxidase-mediated ROS production.",S Kim 2020,2020,1 gene,Kim-2020-Impact of small RNA RaoN on nitrosati,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17649,PHI:11049,,no data found,,,,,,RaoN,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain UK1,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,liver; spleen,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,NaNO2; S-nitrosoglutathione,NaNO2: CHEBI:78870; S-nitrosoglutathione: CHEBI:50091,,,,,gene deletion: full; gene complementation,,,YVS,32279276,PubMed,10.1007/s12275-020-0027-2,J Microbiol. 2020 Jun;58(6):499-506,yhlee@dongseo.ac.kr,"Inactivation of raoN leads to an increase in the intracellular level of reactive oxygen species (ROS) in Salmonella-infected macrophages, suggesting that RaoN is involved in the inhibition of NADPH oxidase-mediated ROS production.",S Kim 2020,2020,1 gene,Kim-2020-Impact of small RNA RaoN on nitrosati,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17650,PHI:11049,,no data found,,,,,,RaoN,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain UK1,colitis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,NaNO2; S-nitrosoglutathione,NaNO2: CHEBI:78870; S-nitrosoglutathione: CHEBI:50091,,,,,gene deletion: full; gene complementation,,,YVS,32279276,PubMed,10.1007/s12275-020-0027-2,J Microbiol. 2020 Jun;58(6):499-506,yhlee@dongseo.ac.kr,"Inactivation of raoN leads to an increase in the intracellular level of reactive oxygen species (ROS) in Salmonella-infected macrophages, suggesting that RaoN is involved in the inhibition of NADPH oxidase-mediated ROS production.",S Kim 2020,2020,1 gene,Kim-2020-Impact of small RNA RaoN on nitrosati,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17651,PHI:11049,,no data found,,,,,,RaoN,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain UK1,colitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,NaNO2; S-nitrosoglutathione,NaNO2: CHEBI:78870; S-nitrosoglutathione: CHEBI:50091,,,,,gene deletion: full; gene complementation,,,YVS,32279276,PubMed,10.1007/s12275-020-0027-2,J Microbiol. 2020 Jun;58(6):499-506,yhlee@dongseo.ac.kr,"Inactivation of raoN leads to an increase in the intracellular level of reactive oxygen species (ROS) in Salmonella-infected macrophages, suggesting that RaoN is involved in the inhibition of NADPH oxidase-mediated ROS production.",S Kim 2020,2020,1 gene,Kim-2020-Impact of small RNA RaoN on nitrosati,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17652,PHI:11050,,no data found,,,,,,CaGpiP1,,,,,,,27357,Colletotrichum acutatum,,Coll-153,anthracnose,eudicots,4072,Capsicum annuum (no common name found),cv. Groupzest,,,fruit,GPI-anchored protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate; iprodione; azoxystrobin; tricyclazole; mannitol; sorbitol; sodium chloride,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; iprodione: CHEBI:28909; azoxystrobin: CHEBI:40909; tricyclazole: CHEBI:81783; mannitol: CHEBI:29864; sorbitol: CHEBI:30911; sodium chloride: CHEBI:26710,,,,,gene deletion: full,,,YVS,33469454,PubMed,10.3389/fmicb.2020.613674,Front Microbiol. 2021 Jan 5;11:613674,mhlee@nchu.edu.tw,CaNRT2.1 was responsible for the growth-defective phenotype.,C C Kuo 2020,2020,3 genes,Kuo-2020-CaNRT2.1 Is Required for Nitrate but,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17653,PHI:11051,,no data found,,,,,,CaNRT2.1,,,,,,,27357,Colletotrichum acutatum,,Coll-153,anthracnose,eudicots,4072,Capsicum annuum (no common name found),cv. Groupzest,,,fruit,membrane-bound nitrate/nitrite transporter,,,,unaffected pathogenicity,,,,,,wild type,,reduced,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate; iprodione; azoxystrobin; tricyclazole; mannitol; sorbitol; sodium chloride,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; iprodione: CHEBI:28909; azoxystrobin: CHEBI:40909; tricyclazole: CHEBI:81783; mannitol: CHEBI:29864; sorbitol: CHEBI:30911; sodium chloride: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,33469454,PubMed,10.3389/fmicb.2020.613674,Front Microbiol. 2021 Jan 5;11:613674,mhlee@nchu.edu.tw,CaNRT2.1 was responsible for the growth-defective phenotype.,C C Kuo 2020,2020,3 genes,Kuo-2020-CaNRT2.1 Is Required for Nitrate but,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17654,PHI:11052,,no data found,,,,,,CaHP1,,,,,,,27357,Colletotrichum acutatum,,Coll-153,anthracnose,eudicots,4072,Capsicum annuum (no common name found),cv. Groupzest,,,fruit,hypothetical protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate; iprodione; azoxystrobin; tricyclazole; mannitol; sorbitol; sodium chloride,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; iprodione: CHEBI:28909; azoxystrobin: CHEBI:40909; tricyclazole: CHEBI:81783; mannitol: CHEBI:29864; sorbitol: CHEBI:30911; sodium chloride: CHEBI:26710,,,,,gene deletion: full,,,YVS,33469454,PubMed,10.3389/fmicb.2020.613674,Front Microbiol. 2021 Jan 5;11:613674,mhlee@nchu.edu.tw,CaNRT2.1 was responsible for the growth-defective phenotype.,C C Kuo 2020,2020,3 genes,Kuo-2020-CaNRT2.1 Is Required for Nitrate but,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17655,PHI:11050,,no data found,,,,,,CaGpiP1,,,,,,,27357,Colletotrichum acutatum,,Coll-153,anthracnose,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,GPI-anchored protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate; iprodione; azoxystrobin; tricyclazole; mannitol; sorbitol; sodium chloride,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; iprodione: CHEBI:28909; azoxystrobin: CHEBI:40909; tricyclazole: CHEBI:81783; mannitol: CHEBI:29864; sorbitol: CHEBI:30911; sodium chloride: CHEBI:26710,,,,,gene deletion: full,,,YVS,33469454,PubMed,10.3389/fmicb.2020.613674,Front Microbiol. 2021 Jan 5;11:613674,mhlee@nchu.edu.tw,CaNRT2.1 was responsible for the growth-defective phenotype.,C C Kuo 2020,2020,3 genes,Kuo-2020-CaNRT2.1 Is Required for Nitrate but,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17656,PHI:11052,,no data found,,,,,,CaHP1,,,,,,,27357,Colletotrichum acutatum,,Coll-153,anthracnose,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,hypothetical protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,Congo red; calcofluor white; sodium dodecyl sulfate; iprodione; azoxystrobin; tricyclazole; mannitol; sorbitol; sodium chloride,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sodium dodecyl sulfate: CHEBI:8984; iprodione: CHEBI:28909; azoxystrobin: CHEBI:40909; tricyclazole: CHEBI:81783; mannitol: CHEBI:29864; sorbitol: CHEBI:30911; sodium chloride: CHEBI:26710,,,,,gene deletion: full,,,YVS,33469454,PubMed,10.3389/fmicb.2020.613674,Front Microbiol. 2021 Jan 5;11:613674,mhlee@nchu.edu.tw,CaNRT2.1 was responsible for the growth-defective phenotype.,C C Kuo 2020,2020,3 genes,Kuo-2020-CaNRT2.1 Is Required for Nitrate but,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17657,PHI:11053,,no data found,GenBank,ABO13801,,,ATCC 17978,zrlA (A1S_3412),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,Zur-regulated lipoprotein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31898255,PubMed,10.1007/s12275-020-9531-7,J Microbiol. 2020 Jan;58(1):67-77,yy1091kwak@gmail.com,ZrlA gene was involved in bacterial adherence and invasion of host epithelial cells.,E K Lee 2020,2020,1 gene,Lee-2020-Zur-regulated lipoprotein A contribut,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17658,PHI:11053,,no data found,GenBank,ABO13801,,,ATCC 17978,zrlA (A1S_3412),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,Zur-regulated lipoprotein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31898255,PubMed,10.1007/s12275-020-9531-7,J Microbiol. 2020 Jan;58(1):67-77,yy1091kwak@gmail.com,ZrlA gene was involved in bacterial adherence and invasion of host epithelial cells.,E K Lee 2020,2020,1 gene,Lee-2020-Zur-regulated lipoprotein A contribut,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17659,PHI:11053,,no data found,GenBank,ABO13801,,,ATCC 17978,zrlA (A1S_3412),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,Zur-regulated lipoprotein A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31898255,PubMed,10.1007/s12275-020-9531-7,J Microbiol. 2020 Jan;58(1):67-77,yy1091kwak@gmail.com,ZrlA gene was involved in bacterial adherence and invasion of host epithelial cells.,E K Lee 2020,2020,1 gene,Lee-2020-Zur-regulated lipoprotein A contribut,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17660,PHI:11054,UniProt,Q4UX46,GenBank,AAY48377,,,8004,XC_1308 (hprK),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,Hpr(ser) kinase/phosphatase,,,,reduced virulence,,,,,,,,,,no,NaCl; sodium dodecyl sulfate; CdCl2; phenol,NaCl: CHEBI:26710; sodium dodecyl sulfate: CHEBI:8984; CdCl2: CHEBI:35456; phenol: CHEBI:15882,,,,,gene deletion: full; gene complementation,,,YVS,31301270,PubMed,10.1111/1462-2920.14740,Environ Microbiol. 2019 Dec;21(12):4504-4520,jltang@gxu.edu.cn,Mutation in HprKXcc reduced the in planta fitness during the symptom development.,R F Li 2019,2019,1 gene,Li-2019-HprKXcc is a serine kinase that regula,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17661,PHI:11055,UniProt,G4MSU6,GenBank,EHA53800,,,70-15,MoHMT1 (MGG_04584),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,HNRNP arginine N-methyltransferase,,,,reduced virulence,,yes,yes,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31478201,PubMed,10.1111/nph.16156,New Phytol. 2020 Jan;225(1):413-429,liuwende@caas.cn,MoHMT1 mutants displayed defects in autophagy induction.,Z Li 2019,2019,4 genes,Li-2019-Arginine methylation is required for r,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17662,PHI:11056,UniProt,G4NC72,GenBank,EHA48221,,,70-15,MoHMT2 (MGG_17318),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31478201,PubMed,10.1111/nph.16156,New Phytol. 2020 Jan;225(1):413-429,liuwende@caas.cn,MoHMT1 mutants displayed defects in autophagy induction.,Z Li 2019,2019,4 genes,Li-2019-Arginine methylation is required for r,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17663,PHI:11057,UniProt,G4MQP0,GenBank,EHA57327,,,70-15,MoRMT2 (MGG_09290),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,arginine N-methyltransferase 2,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31478201,PubMed,10.1111/nph.16156,New Phytol. 2020 Jan;225(1):413-429,liuwende@caas.cn,MoHMT1 mutants displayed defects in autophagy induction.,Z Li 2019,2019,4 genes,Li-2019-Arginine methylation is required for r,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17664,PHI:11058,UniProt,G4NHA5,GenBank,EHA47615,,,70-15,MoHSL7(MGG_03894),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,protein arginine N-methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31478201,PubMed,10.1111/nph.16156,New Phytol. 2020 Jan;225(1):413-429,liuwende@caas.cn,MoHMT1 mutants displayed defects in autophagy induction.,Z Li 2019,2019,4 genes,Li-2019-Arginine methylation is required for r,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17665,PHI:11055,UniProt,G4MSU6,GenBank,EHA53800,,,70-15,MoHMT1 (MGG_04584),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,HNRNP arginine N-methyltransferase,,,,reduced virulence,,yes,yes,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31478201,PubMed,10.1111/nph.16156,New Phytol. 2020 Jan;225(1):413-429,liuwende@caas.cn,MoHMT1 mutants displayed defects in autophagy induction.,Z Li 2019,2019,4 genes,Li-2019-Arginine methylation is required for r,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17666,PHI:11056,UniProt,G4NC72,GenBank,EHA48221,,,70-15,MoHMT2 (MGG_17318),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31478201,PubMed,10.1111/nph.16156,New Phytol. 2020 Jan;225(1):413-429,liuwende@caas.cn,MoHMT1 mutants displayed defects in autophagy induction.,Z Li 2019,2019,4 genes,Li-2019-Arginine methylation is required for r,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17667,PHI:11057,UniProt,G4MQP0,GenBank,EHA57327,,,70-15,MoRMT2 (MGG_09290),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,arginine N-methyltransferase 2,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31478201,PubMed,10.1111/nph.16156,New Phytol. 2020 Jan;225(1):413-429,liuwende@caas.cn,MoHMT1 mutants displayed defects in autophagy induction.,Z Li 2019,2019,4 genes,Li-2019-Arginine methylation is required for r,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17668,PHI:11058,UniProt,G4NHA5,GenBank,EHA47615,,,70-15,MoHSL7(MGG_03894),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,protein arginine N-methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31478201,PubMed,10.1111/nph.16156,New Phytol. 2020 Jan;225(1):413-429,liuwende@caas.cn,MoHMT1 mutants displayed defects in autophagy induction.,Z Li 2019,2019,4 genes,Li-2019-Arginine methylation is required for r,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17669,PHI:11059,UniProt,Q8DPI7,GenBank,AAK99947,,,R6,dprA,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung; spleen,DNA processing protein,,,,reduced virulence,,,,,,,,wild type,,no,SDS; deoxycholate,SDS: CHEBI:8984; deoxycholate: CHEBI:23614,,,,,gene deletion: full,,,YVS,31451619,PubMed,10.1128/IAI.00349-19,Infect Immun. 2019 Oct 18;87(11):e00349-19,geelau@illinois.edu,"The dprA mutant overexpresses ComM, which delays cell separation after division.",J Lin 2019,2019,2 genes,Lin-2019-DprA-dependent exit from the competen,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17670,PHI:11060,,no data found,GenBank,VTQ29196,,,NCTC7978,comM,,,,,,,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung; spleen,competence protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,SDS; deoxycholate,SDS: CHEBI:8984; deoxycholate: CHEBI:23614,,,,,gene deletion: full,,,YVS,31451619,PubMed,10.1128/IAI.00349-19,Infect Immun. 2019 Oct 18;87(11):e00349-19,geelau@illinois.edu,"The dprA mutant overexpresses ComM, which delays cell separation after division.",J Lin 2019,2019,2 genes,Lin-2019-DprA-dependent exit from the competen,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17671,PHI:11059,UniProt,Q8DPI7,GenBank,AAK99947,,,R6,dprA,,,,,,PHI:11060,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung; spleen,DNA processing protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,SDS; deoxycholate,SDS: CHEBI:8984; deoxycholate: CHEBI:23614,,,,,gene deletion: full,,,YVS,31451619,PubMed,10.1128/IAI.00349-19,Infect Immun. 2019 Oct 18;87(11):e00349-19,geelau@illinois.edu,"The dprA mutant overexpresses ComM, which delays cell separation after division.",J Lin 2019,2019,2 genes,Lin-2019-DprA-dependent exit from the competen,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17672,PHI:11060,,no data found,GenBank,VTQ29196,,,NCTC7978,comM,,,,,,PHI:11059,1313,Streptococcus pneumoniae,373153,serotype 2 strain D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasopharynx; lung; spleen,competence protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,SDS; deoxycholate,SDS: CHEBI:8984; deoxycholate: CHEBI:23614,,,,,gene deletion: full,,,YVS,31451619,PubMed,10.1128/IAI.00349-19,Infect Immun. 2019 Oct 18;87(11):e00349-19,geelau@illinois.edu,"The dprA mutant overexpresses ComM, which delays cell separation after division.",J Lin 2019,2019,2 genes,Lin-2019-DprA-dependent exit from the competen,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17673,PHI:11061,UniProt,G4NGN1,GenBank,EHA47391,,,70-15,MoSwa2 (MGG_04080),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,UBA domain-containing protein,,,,reduced virulence,,,yes,yes,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33423301,PubMed,10.1111/nph.17181,New Phytol. 2021 Jan 10,zhgzhang@njau.edu.cn,"Loss of MoSwa2 led to a deficiency in the secretion of extracellular proteins, resulting in both restricted growth of invasive hyphae and reduced inhibition of host immunity.",M Liu 2021,2021,1 gene,Liu-2021-Auxilin-like protein MoSwa2 promotes,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17674,PHI:11062,UniProt,A0A0D2X910,GenBank,KNA94238,,,4287,ZafA (FOXG_00370),chromosome 1,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,ZnSO4,ZnSO4: CHEBI:35176,,,,,gene deletion: full; gene complementation,,,YVS,31750619,PubMed,10.1111/mpp.12891,Mol Plant Pathol. 2020 Feb;21(2):244-249,ge2snlpm@uco.es,"Deletion of zafA results in deactivation of high-affinity zinc transporters, leading to impaired growth under zinc deficiency.",M S Lopez-Berges 2019,2019,1 gene,Lopez-Berges-2019-ZafA-mediated regulation of,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17675,PHI:11062,UniProt,A0A0D2X910,GenBank,KNA94238,,,4287,ZafA (FOXG_00370),chromosome 1,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,ZnSO4,ZnSO4: CHEBI:35176,,,,,gene deletion: full; gene complementation,,,YVS,31750619,PubMed,10.1111/mpp.12891,Mol Plant Pathol. 2020 Feb;21(2):244-249,ge2snlpm@uco.es,"Deletion of zafA results in deactivation of high-affinity zinc transporters, leading to impaired growth under zinc deficiency.",M S Lopez-Berges 2019,2019,1 gene,Lopez-Berges-2019-ZafA-mediated regulation of,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17676,PHI:11063,,no data found,GenBank,OWY42401,,,Z7,Pdel,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,low-affinity cAMP phosphodiesterase,,,,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol; NaCl; KCl; sucrose: CHEBI:17992; H2O2; Congo red; sodium dodecyl sulfate; VK3,sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; sucrose: CHEBI:17992; H2O2: CHEBI:16240; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; VK3: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,33365022,PubMed,10.3389/fmicb.2020.597545,Front Microbiol. 2020 Dec 7;11:597545,tangkezhi@cric.cn,"AaPdel, but not AaPdeh, was found to be a key regulator in conidiation and pathogenesis in A. alternata.",W Lv 2020,2020,2 genes,"Lv-2020-Pdel, Encoding a Low-Affinity cAMP Pho",BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17677,PHI:11064,,no data found,GenBank,OWY42000,,,Z7,Pdeh,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,high-affinity cAMP phosphodiesterase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,sorbitol; NaCl; KCl; sucrose: CHEBI:17992; H2O2; Congo red; sodium dodecyl sulfate; VK3,sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; sucrose: CHEBI:17992; H2O2: CHEBI:16240; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; VK3: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,33365022,PubMed,10.3389/fmicb.2020.597545,Front Microbiol. 2020 Dec 7;11:597545,tangkezhi@cric.cn,"AaPdel, but not AaPdeh, was found to be a key regulator in conidiation and pathogenesis in A. alternata.",W Lv 2020,2020,2 genes,"Lv-2020-Pdel, Encoding a Low-Affinity cAMP Pho",BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17678,PHI:11065,UniProt,A0A0F6AZV0,GenBank,ACY87774,,,14028S,STM14_1285 (AsiR),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,putative RpiR-family transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33410728,PubMed,10.1080/21505594.2020.1870331,Virulence. 2021 Dec;12(1):298-311,fenglu63@nankai.edu.cn,Overexpression of asiR enhanced the survival of infected mice.,S Ma 2021,2021,1 gene,Ma-2021-Downregulation of a novel flagellar sy,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17679,PHI:11065,UniProt,A0A0F6AZV0,GenBank,ACY87774,,,14028S,STM14_1285 (AsiR),,,,,,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative RpiR-family transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33410728,PubMed,10.1080/21505594.2020.1870331,Virulence. 2021 Dec;12(1):298-311,fenglu63@nankai.edu.cn,AsiR contributed negatively to the growth of S. Typhimurium in host macrophages.,S Ma 2021,2021,1 gene,Ma-2021-Downregulation of a novel flagellar sy,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17680,PHI:11066,UniProt,I6QM72,GenBank,AGN94862,,,PA42,oprF,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,embryo,major outer membrane porin,,,,reduced virulence,,,,,,,,,,no,bafilomycin A1,bafilomycin A1: CHEBI:22689,,,,,gene deletion: full,,,YVS,33432030,PubMed,10.1038/s41598-020-79678-0,Sci Rep. 2021 Jan 11;11(1):359,anne.blanc-potard@umontpellier.fr,OprF mutant strain was better cleared than wild-type strain in a macrophage dependent manner in the zebrafish embryo model.,M Moussouni 2021,2021,1 gene,Moussouni-2021-Pseudomonas aeruginosa OprF pla,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17681,PHI:11066,UniProt,I6QM72,GenBank,AGN94862,,,PA42,oprF,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,major outer membrane porin,,,,reduced virulence,,,,,,,,,,no,bafilomycin A1,bafilomycin A1: CHEBI:22689,,,,,gene deletion: full,,,YVS,33432030,PubMed,10.1038/s41598-020-79678-0,Sci Rep. 2021 Jan 11;11(1):359,anne.blanc-potard@umontpellier.fr,"Intramacrophage survival defect of P. aeruginosa oprF mutant, which was correlated with elevated association of bacteria with acidic compartments.",M Moussouni 2021,2021,1 gene,Moussouni-2021-Pseudomonas aeruginosa OprF pla,BATCH_104A,2021-01-01,MC,,,,,,,,,,,,,
,,Record 17682,PHI:11067,UniProt,A0A0S4WLR3,GenBank,CUV59635,,,Phyl III-seqv23,ompA,,,,,,,305,Ralstonia solanacearum,1394180,Rs-09-161,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Agassaim,,,leaf,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32656057,PubMed,10.1007/s13205-020-02311-4,3 Biotech. 2020 Jul;10(7):324,trupti_00@yahoo.com,The T6SS mutants showed significant reduction of wilt on eggplant.,T Asolkar 2020,2020,5 genes,Asolkar-2020-The involvement of the Type Six S,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17683,PHI:11068,UniProt,no data found,GenBank,CEJ17129,,,IPO1609,vgrG3,,,,,,,305,Ralstonia solanacearum,1394180,Rs-09-161,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Agassaim,,,leaf,type VI secretion-associated VGR-related protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32656057,PubMed,10.1007/s13205-020-02311-4,3 Biotech. 2020 Jul;10(7):324,trupti_00@yahoo.com,The T6SS mutants showed significant reduction of wilt on eggplant.,T Asolkar 2020,2020,5 genes,Asolkar-2020-The involvement of the Type Six S,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17684,PHI:11069,UniProt,no data found,GenBank,QOK88964,,,UW763,hcp,,,,,,,305,Ralstonia solanacearum,1394180,Rs-09-161,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Agassaim,,,leaf,type VI secretion system tube protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32656057,PubMed,10.1007/s13205-020-02311-4,3 Biotech. 2020 Jul;10(7):324,trupti_00@yahoo.com,The T6SS mutants showed significant reduction of wilt on eggplant.,T Asolkar 2020,2020,5 genes,Asolkar-2020-The involvement of the Type Six S,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17685,PHI:11070,UniProt,A0A5H2Q4P9,GenBank,AYB63031,,,IBSBF 2571,tssH,,,,,,,305,Ralstonia solanacearum,1394180,Rs-09-161,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Agassaim,,,leaf,type VI secretion system ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32656057,PubMed,10.1007/s13205-020-02311-4,3 Biotech. 2020 Jul;10(7):324,trupti_00@yahoo.com,The T6SS mutants showed significant reduction of wilt on eggplant.,T Asolkar 2020,2020,5 genes,Asolkar-2020-The involvement of the Type Six S,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17686,PHI:11071,UniProt,A0A5H2Q8Z8,GenBank,AYB63037,,,IBSBF 2571,tssM,,,,,,,305,Ralstonia solanacearum,1394180,Rs-09-161,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Agassaim,,,leaf,type VI secretion system membrane subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32656057,PubMed,10.1007/s13205-020-02311-4,3 Biotech. 2020 Jul;10(7):324,trupti_00@yahoo.com,The T6SS mutants showed significant reduction of wilt on eggplant.,T Asolkar 2020,2020,5 genes,Asolkar-2020-The involvement of the Type Six S,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17687,PHI:11072,UniProt,Q4WRP6,GenBank,EAL90886,,,Af293,ftsA (Afu1g15570),chromosome 1,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"ubiquitin-conjugating enzyme, putative",,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32378777,PubMed,10.1111/tra.12735,Traffic. 2020 Jul;21(7):479-487,me021@uark.edu,"Contact-induced hyphal branching behaviors were impaired in ΔftsA mutants, but FtsA-mediated early endosome motility was dispensable for virulence in an invertebrate infection model.",B D Bieger 2020,2020,1 gene,Bieger-2020-Long-distance early endosome motil,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17688,PHI:11073,UniProt,P0CQ08,GenBank,AAW43174,,,JEC21,pol3,,pol3 D270G,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcal meningitis,rodents,10090,Mus musculus (related: house mouse),A/JCr,,,lung; brain,DNA polymerase 3,,,,unaffected pathogenicity,,,,,,,,,,no,fluconazole,fluconazole: CHEBI:46081,,,,,gene mutation,,,YVS,31838381,PubMed,10.1016/j.dnarep.2019.102751,DNA Repair (Amst). 2020 Feb;86:102751,kylieboyce@rmit.edu.au,Hypermutator phenotype of the pol3D270G mutant caused rapid microevolution in vitro but did not result in decreased virulence.,K J Boyce 2020,2020,1 gene,Boyce-2020-A spontaneous mutation in DNA polym,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17689,PHI:11074,UniProt,Q9A0K1,GenBank,AAK33689,,,M1,scfC (Spy0743),,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,soft-tissue,"ABC importer, substrate-binding protein",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31591169,PubMed,10.1128/IAI.00613-19,Infect Immun. 2019 Nov 18;87(12):e00613-19,kmciver@umd.edu,"The ΔscfC substrate-binding and ΔscfD permease mutants, but not the ΔscfE ATPase mutant, were highly attenuated in murine soft tissue.",R E Braza 2019,2019,3 genes,Braza-2019-The scfCDE Operon Encodes a Predict,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17690,PHI:11075,UniProt,Q9A0J9,GenBank,AAK33691,,,SF370,scfD (Spy0745),,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,soft-tissue,ABC transporter (ATP-binding protein)-streptolysin S associated ORF,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31591169,PubMed,10.1128/IAI.00613-19,Infect Immun. 2019 Nov 18;87(12):e00613-19,kmciver@umd.edu,"The ΔscfC substrate-binding and ΔscfD permease mutants, but not the ΔscfE ATPase mutant, were highly attenuated in murine soft tissue.",R E Braza 2019,2019,3 genes,Braza-2019-The scfCDE Operon Encodes a Predict,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17691,PHI:11076,UniProt,Q9A0J8,GenBank,AAK33692,,,SF370,scfE (Spy0746),,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,soft-tissue,putative ABC transporter (ATP-binding protein),,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31591169,PubMed,10.1128/IAI.00613-19,Infect Immun. 2019 Nov 18;87(12):e00613-19,kmciver@umd.edu,"The ΔscfC substrate-binding and ΔscfD permease mutants, but not the ΔscfE ATPase mutant, were highly attenuated in murine soft tissue.",R E Braza 2019,2019,3 genes,Braza-2019-The scfCDE Operon Encodes a Predict,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17692,PHI:11074,UniProt,Q9A0K1,GenBank,AAK33689,,,M1,scfC (Spy0743),,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,infection,primates,9606,Homo sapiens (related: human),,,,blood,"ABC importer, substrate-binding protein",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31591169,PubMed,10.1128/IAI.00613-19,Infect Immun. 2019 Nov 18;87(12):e00613-19,kmciver@umd.edu,Each of the individual ΔscfCDE mutants exhibited significant survival and growth defects in whole human blood compared to the WT.,R E Braza 2019,2019,3 genes,Braza-2019-The scfCDE Operon Encodes a Predict,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17693,PHI:11075,UniProt,Q9A0J9,GenBank,AAK33691,,,SF370,scfD (Spy0745),,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,infection,primates,9606,Homo sapiens (related: human),,,,blood,ABC transporter (ATP-binding protein)-streptolysin S associated ORF,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31591169,PubMed,10.1128/IAI.00613-19,Infect Immun. 2019 Nov 18;87(12):e00613-19,kmciver@umd.edu,Each of the individual ΔscfCDE mutants exhibited significant survival and growth defects in whole human blood compared to the WT.,R E Braza 2019,2019,3 genes,Braza-2019-The scfCDE Operon Encodes a Predict,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17694,PHI:11076,UniProt,Q9A0J8,GenBank,AAK33692,,,SF370,scfE (Spy0746),,,,,,,1314,Streptococcus pyogenes,,GAS M1T1 5448,infection,primates,9606,Homo sapiens (related: human),,,,blood,putative ABC transporter (ATP-binding protein),,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,31591169,PubMed,10.1128/IAI.00613-19,Infect Immun. 2019 Nov 18;87(12):e00613-19,kmciver@umd.edu,Each of the individual ΔscfCDE mutants exhibited significant survival and growth defects in whole human blood compared to the WT.,R E Braza 2019,2019,3 genes,Braza-2019-The scfCDE Operon Encodes a Predict,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17695,PHI:11077,UniProt,K3VEN3,GenBank,EKJ72622,,,CS3096,fpbir1 (FPSE_07259),,,,,,,101028,Fusarium pseudograminearum,,WZ2-8A,Fusarium crown rot; Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Aikang 58,,,coleoptile,putative apoptosis inhibitor,,,,reduced virulence,,,,,,reduced,reduced; aberrant,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33408234,PubMed,10.1128/mSphere.01140-20,mSphere. 2021 Jan 6;6(1):e01140-20,honglianli@sina.com,"An FpBIR1 deletion mutant showed reductions in conidial germination and pathogenicity, whereas FpNUC1 deletion enhanced conidial germination and pathogenesis of F. pseudograminearum.",L Chen 2021,2021,2 genes,Chen-2021-Analysis of Apoptosis-Related Genes,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17696,PHI:11078,UniProt,K3VS45,GenBank,EKJ78099,,,CS3096,fpnuc1 (FPSE_01560),,,,,,,101028,Fusarium pseudograminearum,,WZ2-8A,Fusarium crown rot; Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),,,,leaf,endonuclease,,,,unaffected pathogenicity,,,,,,reduced,reduced; aberrant,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33408234,PubMed,10.1128/mSphere.01140-20,mSphere. 2021 Jan 6;6(1):e01140-20,honglianli@sina.com,"An FpBIR1 deletion mutant showed reductions in conidial germination and pathogenicity, whereas FpNUC1 deletion enhanced conidial germination and pathogenesis of F. pseudograminearum.",L Chen 2021,2021,2 genes,Chen-2021-Analysis of Apoptosis-Related Genes,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17697,PHI:11079,UniProt,A0A0H2XJD2,GenBank,ABD22912,,,USA300_FPR3757,eep (SAUSA300_1155),,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; kidney; liver,putative membrane associated zinc metalloprotease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32457050,PubMed,10.1128/JB.00046-20,J Bacteriol. 2020 Jul 9;202(15):e00046-20,qq2005011@163.com,Eep deletion reduced staphylococcal resistance to killing by human neutrophils as well as survival in a murine model of blood infection.,D Cheng 2020,2020,1 gene,Cheng-2020-The roles of the site-2 protease Ee,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17698,PHI:11079,UniProt,A0A0H2XJD2,GenBank,ABD22912,,,USA300_FPR3757,eep (SAUSA300_1155),,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,neutrophil,putative membrane associated zinc metalloprotease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32457050,PubMed,10.1128/JB.00046-20,J Bacteriol. 2020 Jul 9;202(15):e00046-20,qq2005011@163.com,Eep deletion reduced staphylococcal resistance to killing by human neutrophils as well as survival in a murine model of blood infection.,D Cheng 2020,2020,1 gene,Cheng-2020-The roles of the site-2 protease Ee,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17699,PHI:11079,UniProt,A0A0H2XJD2,GenBank,ABD22912,,,USA300_FPR3757,eep (SAUSA300_1155),,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,putative membrane associated zinc metalloprotease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32457050,PubMed,10.1128/JB.00046-20,J Bacteriol. 2020 Jul 9;202(15):e00046-20,qq2005011@163.com,Eep deletion decreased the adherence of S. aureus to host epithelial cells.,D Cheng 2020,2020,1 gene,Cheng-2020-The roles of the site-2 protease Ee,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17700,PHI:11080,UniProt,O25748,GenBank,AAD08168,,,26695,slyD,,,,niuD,,,210,Helicobacter pylori,992116,SS1,gastric infection,rodents,10090,Mus musculus (related: house mouse),NMRI,,,stomach,peptidyl-prolyl cis-trans isomerase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33444370,PubMed,10.1371/journal.ppat.1009193,PLoS Pathog. 2021 Jan 14;17(1):e1009193,hdereuse@pasteur.fr,SlyD inactivation resulted in reduced intracellular nickel availability.,M Denic 2021,2021,1 gene,Denic-2021-A novel mode of control of nickel u,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17701,PHI:11081,UniProt,Q0PCA6,GenBank,CAL34200,,,NCTC 11168,tlp10 (Cj0019c),,,,,,,197,Campylobacter jejuni,192222,NCTC 11168-O,gastroenteritis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,HCT-116 cell,putative MCP-domain signal transduction protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33402336,PubMed,10.1126/scisignal.abc8521,Sci Signal. 2021 Jan 5;14(664):eabc8521,v.korolik@griffith.edu.au,"A tlp10 mutant strain lacking the ligand-binding sites was attenuated in its ability to colonize avian caeca and to adhere to cultured human intestinal cells, indicating the potential involvement of the DAHL domain in host colonization and disease.",B A Elgamoudi 2021,2021,1 gene,Elgamoudi-2021-The Campylobacter jejuni chemor,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17702,PHI:11081,UniProt,Q0PCA6,GenBank,CAL34200,,,NCTC 11168,tlp10 (Cj0019c),,,,,,,197,Campylobacter jejuni,192222,NCTC 11168-O,gastroenteritis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,putative MCP-domain signal transduction protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33402336,PubMed,10.1126/scisignal.abc8521,Sci Signal. 2021 Jan 5;14(664):eabc8521,v.korolik@griffith.edu.au,"A tlp10 mutant strain lacking the ligand-binding sites was attenuated in its ability to colonize avian caeca and to adhere to cultured human intestinal cells, indicating the potential involvement of the DAHL domain in host colonization and disease.",B A Elgamoudi 2021,2021,1 gene,Elgamoudi-2021-The Campylobacter jejuni chemor,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17703,PHI:11081,UniProt,Q0PCA6,GenBank,CAL34200,,,NCTC 11168,tlp10 (Cj0019c),,,,,,,197,Campylobacter jejuni,192222,NCTC 11168-O,gastroenteritis,birds,9031,Gallus gallus (related: chicken),,,,cecum,putative MCP-domain signal transduction protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33402336,PubMed,10.1126/scisignal.abc8521,Sci Signal. 2021 Jan 5;14(664):eabc8521,v.korolik@griffith.edu.au,"A tlp10 mutant strain lacking the ligand-binding sites was attenuated in its ability to colonize avian caeca and to adhere to cultured human intestinal cells, indicating the potential involvement of the DAHL domain in host colonization and disease.",B A Elgamoudi 2021,2021,1 gene,Elgamoudi-2021-The Campylobacter jejuni chemor,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17704,PHI:11082,UniProt,G4NGK7,GenBank,EHA47367,,,70-15,MoSep1 (MGG_04100),chromosome 6,,,MoMkk1,UniProt: G4NGK7; GenBank: EHA47367,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,STE/STE11/CDC15 protein kinase,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,,no,nocodazole; calcofluor white,nocodazole: CHEBI:34892; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33411855,PubMed,10.1371/journal.ppat.1009080,PLoS Pathog. 2021 Jan 7;17(1):e1009080,zhgzhang@njau.edu.cn,MoSep1-dependent MoMkk1 phosphorylation was essential for the development and pathogenicity of M.oryzae.,W Feng 2021,2021,4 genes,Feng-2021-Balancing of the mitotic exit networ,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17705,PHI:11083,UniProt,G4NJ37,GenBank,EHA46253,,,70-15,MoDbf2 (MGG_02757),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,AGC/NDR protein kinase,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,,no,nocodazole; calcofluor white,nocodazole: CHEBI:34892; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33411855,PubMed,10.1371/journal.ppat.1009080,PLoS Pathog. 2021 Jan 7;17(1):e1009080,zhgzhang@njau.edu.cn,MoSep1-dependent MoMkk1 phosphorylation was essential for the development and pathogenicity of M.oryzae.,W Feng 2021,2021,4 genes,Feng-2021-Balancing of the mitotic exit networ,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17706,PHI:11084,UniProt,G4NAT2,GenBank,EHA50524,,,70-15,MoMob1 (MGG_03151),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,maintenance-ploidy protein mob1,,,,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,,no,nocodazole; calcofluor white,nocodazole: CHEBI:34892; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33411855,PubMed,10.1371/journal.ppat.1009080,PLoS Pathog. 2021 Jan 7;17(1):e1009080,zhgzhang@njau.edu.cn,MoSep1-dependent MoMkk1 phosphorylation was essential for the development and pathogenicity of M.oryzae.,W Feng 2021,2021,4 genes,Feng-2021-Balancing of the mitotic exit networ,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17707,PHI:11085,UniProt,G4N6Z6,GenBank,EHA50761,,,70-15,MoMkk1 (MGG_06482),,"MoMkk1S19D-GFP, MoMkk1S125D-GFP, MoMkk1S136D-GFP, MoMkk1T207D-GFP, MoMkk1T24D-GFP, phosphomimic mutation of MoMkk16D",,MoSep1,UniProt: G4N6Z6; GenBank: EHA50761,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,STE/STE7 protein kinase,,,,unaffected pathogenicity,,yes,yes,,,reduced; aberrant,,reduced,,no,nocodazole; calcofluor white,nocodazole: CHEBI:34892; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33411855,PubMed,10.1371/journal.ppat.1009080,PLoS Pathog. 2021 Jan 7;17(1):e1009080,zhgzhang@njau.edu.cn,MoSep1-dependent MoMkk1 phosphorylation was essential for the development and pathogenicity of M.oryzae.,W Feng 2021,2021,4 genes,Feng-2021-Balancing of the mitotic exit networ,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17708,PHI:11086,,no data found,,,,,,caeB (CBU1532),,,,,,,777,Coxiella burnetii,,RSA 439,Q fever,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33355405,PubMed,10.1111/cmi.13305,Cell Microbiol. 2020 Dec 23,anja.luehrmann@uk-erlangen.de,"Reduced replication and reduced size of the CCV in larvae infected with the ΔcaeB mutant was observed, suggesting virulence of C. burnetii lacking CaeB was attenuated in vivo.",A Friedrich 2020,2020,1 gene,Friedrich-2020-The Coxiella burnetii effector,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17709,PHI:11087,UniProt,A0A177DXR7,GenBank,QIH29420,,,Z7,metB (MN812273),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),,,,leaf,cystathionine gamma-synthase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,chlorothalonil; CuSO4; NaCl; camptothecin; hydroxyurea; Congo red; H2O2,chlorothalonil: CHEBI:3639; CuSO4: CHEBI:23414; NaCl: CHEBI:26710; camptothecin: CHEBI:27656; hydroxyurea: CHEBI:44423; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33277273,PubMed,10.1128/AEM.01911-20,Appl Environ Microbiol. 2020 Dec 4:AEM.01911-20,hyli@zju.edu.cn,"Loss of pathogenicity of ΔMetB, ΔMetC, and ΔMetX mutants was caused by the deficiency of methionine biosynthesis.",Y Gai 2020,2020,3 genes,Gai-2020-The critical role of MetR_MetB_MetC_M,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17710,PHI:11088,UniProt,A0A6G7BN60,GenBank,QIH29421,,,Z7,metC (MN812274),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),,,,leaf,cystathionine beta-lyase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,chlorothalonil; CuSO4; NaCl; camptothecin; hydroxyurea; Congo red; H2O2,chlorothalonil: CHEBI:3639; CuSO4: CHEBI:23414; NaCl: CHEBI:26710; camptothecin: CHEBI:27656; hydroxyurea: CHEBI:44423; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33277273,PubMed,10.1128/AEM.01911-20,Appl Environ Microbiol. 2020 Dec 4:AEM.01911-20,hyli@zju.edu.cn,"Loss of pathogenicity of ΔMetB, ΔMetC, and ΔMetX mutants was caused by the deficiency of methionine biosynthesis.",Y Gai 2020,2020,3 genes,Gai-2020-The critical role of MetR_MetB_MetC_M,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17711,PHI:11089,UniProt,A0A6G7BN58,GenBank,QIH29422,,,Z7,metX (MN812275),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),,,,leaf,homoserine O-acetyltransferase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,chlorothalonil; CuSO4; NaCl; camptothecin; hydroxyurea; Congo red; H2O2,chlorothalonil: CHEBI:3639; CuSO4: CHEBI:23414; NaCl: CHEBI:26710; camptothecin: CHEBI:27656; hydroxyurea: CHEBI:44423; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33277273,PubMed,10.1128/AEM.01911-20,Appl Environ Microbiol. 2020 Dec 4:AEM.01911-20,hyli@zju.edu.cn,"Loss of pathogenicity of ΔMetB, ΔMetC, and ΔMetX mutants was caused by the deficiency of methionine biosynthesis.",Y Gai 2020,2020,3 genes,Gai-2020-The critical role of MetR_MetB_MetC_M,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17712,PHI:11090,UniProt,A4VWD1,GenBank,ABP90420,,,05ZYH33,mnmE,,,,,,PHI:11091,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),Kunming,,,blood; brain; lung,tRNA modification GTPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33425782,PubMed,10.3389/fcimb.2020.597408,Front Cell Infect Microbiol. 2020 Dec 11;10:597408,tyxanbit@163.com,"Double knock out strain displayed decrease in arginine consumption and ammonia production, deficient growth, and attenuated pathogenicity.",T Gao 2020,2020,2 genes,Gao-2020-Proteomic and Metabolomic Analyses Pr,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17713,PHI:11091,UniProt,A4VYE0,GenBank,ABP91129,,,05ZYH33,gidA,,,,,,PHI:11090,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),Kunming,,,blood; brain; lung,tRNA uridine 5-carboxymethylaminomethyl modification enzyme,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33425782,PubMed,10.3389/fcimb.2020.597408,Front Cell Infect Microbiol. 2020 Dec 11;10:597408,tyxanbit@163.com,"Double knock out strain displayed decrease in arginine consumption and ammonia production, deficient growth, and attenuated pathogenicity.",T Gao 2020,2020,2 genes,Gao-2020-Proteomic and Metabolomic Analyses Pr,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17714,PHI:11092,UniProt,A0A385ER39,GenBank,AXQ88673,,,WM99c,oprD,,,,,,,470,Acinetobacter baumannii,,isolate ST2/KL22,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33258407,PubMed,10.1080/21505594.2020.1856560,Virulence. 2021 Dec;12(1):1-11,liang@ccmu.edu.cn,The knock-out of oprD in high-virulent isolate resulted in virulence attenuation.,M Hua 2021,2021,1 gene,Hua-2021-The novel outer membrane protein from,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17715,PHI:11093,UniProt,P0AFV4,GenBank,AAC75236,,,K-12,MepS,,,,,,,562,Escherichia coli,364106,UTI89,infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney,peptidoglycan DD-endopeptidase/peptidoglycan LD-carboxypeptidase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33391204,PubMed,10.3389/fmicb.2020.586214,Front Microbiol. 2020 Dec 16;11:586214,chteng@mail.ncku.edu.tw,Spr deficiency attenuated the ability of UPEC to infect kidneys and induced a fitness defect during bladder colonization in a mouse model of UTI.,W C Huang 2020,2020,1 gene,Huang-2020-Peptidoglycan Endopeptidase Spr of,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17716,PHI:11094,UniProt,no data found,GenBank,CBJ46674,,,ATCC 49946,eagA (EAM_1999),,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,"D,D-endopeptidase of metallopeptidase class",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33281804,PubMed,10.3389/fmicb.2020.605265,Front Microbiol. 2020 Nov 17;11:605265,sundin@msu.edu,An eagA deletion mutant (Ea11891eagA) was significantly reduced in virulence compared to the wild type E. amylovora Ea1189.,R R Kharadi 2020,2020,5 genes,Kharadi-2020-Cyclic-di-GMP Regulates Autoaggre,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17717,PHI:11095,,no data found,,,,,,pdeA,,,,,,PHI:11096; PHI:11097; PHI:11094,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,c-di-GMP specific phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33281804,PubMed,10.3389/fmicb.2020.605265,Front Microbiol. 2020 Nov 17;11:605265,sundin@msu.edu,An eagA deletion mutant (Ea11891eagA) was significantly reduced in virulence compared to the wild type E. amylovora Ea1189.,R R Kharadi 2020,2020,5 genes,Kharadi-2020-Cyclic-di-GMP Regulates Autoaggre,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17718,PHI:11096,,no data found,,,,,,pdeB,,,,,,PHI:11095; PHI:11097; PHI:11094,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,c-di-GMP specific phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33281804,PubMed,10.3389/fmicb.2020.605265,Front Microbiol. 2020 Nov 17;11:605265,sundin@msu.edu,An eagA deletion mutant (Ea11891eagA) was significantly reduced in virulence compared to the wild type E. amylovora Ea1189.,R R Kharadi 2020,2020,5 genes,Kharadi-2020-Cyclic-di-GMP Regulates Autoaggre,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17719,PHI:11097,,no data found,,,,,,pdeC,,,,,,PHI:11095; PHI:11096; PHI:11094,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,c-di-GMP specific phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33281804,PubMed,10.3389/fmicb.2020.605265,Front Microbiol. 2020 Nov 17;11:605265,sundin@msu.edu,An eagA deletion mutant (Ea11891eagA) was significantly reduced in virulence compared to the wild type E. amylovora Ea1189.,R R Kharadi 2020,2020,5 genes,Kharadi-2020-Cyclic-di-GMP Regulates Autoaggre,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17720,PHI:11094,UniProt,no data found,GenBank,CBJ46674,,,ATCC 49946,eagA (EAM_1999),,,,,,PHI:11095; PHI:11096; PHI:11097,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,c-di-GMP specific phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33281804,PubMed,10.3389/fmicb.2020.605265,Front Microbiol. 2020 Nov 17;11:605265,sundin@msu.edu,An eagA deletion mutant (Ea11891eagA) was significantly reduced in virulence compared to the wild type E. amylovora Ea1189.,R R Kharadi 2020,2020,5 genes,Kharadi-2020-Cyclic-di-GMP Regulates Autoaggre,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17721,PHI:11095,,no data found,,,,,,pdeA,,,,,,PHI:11096; PHI:11097; PHI:11098,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,c-di-GMP specific phosphodiesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33281804,PubMed,10.3389/fmicb.2020.605265,Front Microbiol. 2020 Nov 17;11:605265,sundin@msu.edu,An eagA deletion mutant (Ea11891eagA) was significantly reduced in virulence compared to the wild type E. amylovora Ea1189.,R R Kharadi 2020,2020,5 genes,Kharadi-2020-Cyclic-di-GMP Regulates Autoaggre,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17722,PHI:11096,,no data found,,,,,,pdeB,,,,,,PHI:11095; PHI:11097; PHI:11098,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,c-di-GMP specific phosphodiesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33281804,PubMed,10.3389/fmicb.2020.605265,Front Microbiol. 2020 Nov 17;11:605265,sundin@msu.edu,An eagA deletion mutant (Ea11891eagA) was significantly reduced in virulence compared to the wild type E. amylovora Ea1189.,R R Kharadi 2020,2020,5 genes,Kharadi-2020-Cyclic-di-GMP Regulates Autoaggre,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17723,PHI:11097,,no data found,,,,,,pdeC,,,,,,PHI:11095; PHI:11096; PHI:11098,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,c-di-GMP specific phosphodiesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33281804,PubMed,10.3389/fmicb.2020.605265,Front Microbiol. 2020 Nov 17;11:605265,sundin@msu.edu,An eagA deletion mutant (Ea11891eagA) was significantly reduced in virulence compared to the wild type E. amylovora Ea1189.,R R Kharadi 2020,2020,5 genes,Kharadi-2020-Cyclic-di-GMP Regulates Autoaggre,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17724,PHI:11098,UniProt,no data found,GenBank,CBJ44942,,,ATCC 49946,zur (EAM_0267),,,,,,PHI:11095; PHI:11096; PHI:11097,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,zinc uptake regulation protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33281804,PubMed,10.3389/fmicb.2020.605265,Front Microbiol. 2020 Nov 17;11:605265,sundin@msu.edu,An eagA deletion mutant (Ea11891eagA) was significantly reduced in virulence compared to the wild type E. amylovora Ea1189.,R R Kharadi 2020,2020,5 genes,Kharadi-2020-Cyclic-di-GMP Regulates Autoaggre,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17725,PHI:11099,UniProt,B7UMA6,GenBank,CAS11496,,,E2348/69,escN,,,,,,,562,Escherichia coli,,EPEC E2348/69,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,ileum; colon; cecum,H(+)-transporting two-sector ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33392105,PubMed,10.3389/fcimb.2020.595266,Front Cell Infect Microbiol. 2020 Dec 17;10:595266,ellenledwaba@gmail.com,The escN mutant colonized the mice with no weight loss or increased inflammatory biomarkers.,S E Ledwaba 2020,2020,1 gene,Ledwaba-2020-Enteropathogenic Escherichia coli,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17726,PHI:11100,UniProt,P0CM08,GenBank,AAW45303,,,JEC21,yst1 (CNI04050),,,,,,,5207,Cryptococcus neoformans,214684,JEC21,fungal meningitis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,conserved protein,,,,reduced virulence,,,,,,,,,,no,NaCl; KCl; Congo red,NaCl: CHEBI:26710; KCl: CHEBI:32588; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,33440003,PubMed,10.1093/femsyr/foab001,FEMS Yeast Res. 2021 Jan 13:foab001,zhu11187@bnu.edu.cn,"The mutant strain was hypersensitive to low temperature and anti-ribosomal drugs, which was putatively attributed to the impairment in ribosomal function.",C Li 2021,2021,1 gene,Li-2021-Epigenetic regulation of virulence and,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17727,PHI:11101,UniProt,G4NHH2,GenBank,EHA47682,,,70-15,UPL3 (MGG_03841),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,E3 ubiquitin-protein ligase,,,,reduced virulence,,no,no,yes,,,,,,no,H2O2; menadione; diamide,H2O2: CHEBI:16240; menadione: CHEBI:28869; diamide: CHEBI:48958,,,,,gene deletion: full,,,YVS,31828801,PubMed,10.1111/nph.16365,New Phytol. 2020 Apr;226(2):523-540,rwilson10@unl.edu,"Deleting UPL3 depleted Sir2 during growth in rice cells, triggering host immunity and preventing infection.",G Li 2019,2019,2 genes,Li-2019-Terminating rice innate immunity induc,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17728,PHI:11102,UniProt,A0A151V4L8,GenBank,KYQ30515,,,70-15,SIR2 (MGG_10267),,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,deacetylase sirtuin-type domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; menadione; diamide,H2O2: CHEBI:16240; menadione: CHEBI:28869; diamide: CHEBI:48958,,,,,altered gene expression / gene regulation: overexpression,,,YVS,31828801,PubMed,10.1111/nph.16365,New Phytol. 2020 Apr;226(2):523-540,rwilson10@unl.edu,"Deleting UPL3 depleted Sir2 during growth in rice cells, triggering host immunity and preventing infection.",G Li 2019,2019,2 genes,Li-2019-Terminating rice innate immunity induc,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17729,PHI:11103,UniProt,A0A125YKR6,GenBank,ESS34268,,,VEG,AAT,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,aspartate aminotransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31907178,PubMed,10.1128/AAC.01889-19,Antimicrob Agents Chemother. 2020 Feb 21;64(3):e01889-19,gen@obihiro.ac.jp,"Deficiency of AAT in both RH and PLK did not reduce the virulence in mice, although the growth ability of the parasites was affected in vitro.",J Li 2020,2020,1 gene,Li-2020-Hydroxylamine and Carboxymethoxylamine,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17730,PHI:11103,UniProt,A0A125YKR6,GenBank,ESS34268,,,VEG,AAT,,,,,,,5811,Toxoplasma gondii,,PLK,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,aspartate aminotransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31907178,PubMed,10.1128/AAC.01889-19,Antimicrob Agents Chemother. 2020 Feb 21;64(3):e01889-19,gen@obihiro.ac.jp,"Deficiency of AAT in both RH and PLK did not reduce the virulence in mice, although the growth ability of the parasites was affected in vitro.",J Li 2020,2020,1 gene,Li-2020-Hydroxylamine and Carboxymethoxylamine,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17731,PHI:11103,UniProt,A0A125YKR6,GenBank,ESS34268,,,VEG,AAT,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,aspartate aminotransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31907178,PubMed,10.1128/AAC.01889-19,Antimicrob Agents Chemother. 2020 Feb 21;64(3):e01889-19,gen@obihiro.ac.jp,"Deficiency of AAT in both RH and PLK did not reduce the virulence in mice, although the growth ability of the parasites was affected in vitro.",J Li 2020,2020,1 gene,Li-2020-Hydroxylamine and Carboxymethoxylamine,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17732,PHI:11103,UniProt,A0A125YKR6,GenBank,ESS34268,,,VEG,AAT,,,,,,,5811,Toxoplasma gondii,,PLK,toxoplasmosis,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,aspartate aminotransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31907178,PubMed,10.1128/AAC.01889-19,Antimicrob Agents Chemother. 2020 Feb 21;64(3):e01889-19,gen@obihiro.ac.jp,"Deficiency of AAT in both RH and PLK did not reduce the virulence in mice, although the growth ability of the parasites was affected in vitro.",J Li 2020,2020,1 gene,Li-2020-Hydroxylamine and Carboxymethoxylamine,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17733,PHI:11104,,no data found,,,,,,PcAvh103,,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31997517,PubMed,10.1111/mpp.12912,Mol Plant Pathol. 2020 Apr;21(4):502-511,meixiangzhang@njau.edu.cn,P. capsici RxLR effector PcAvh103 targeted host EDS1 to suppress plant immunity.,Q Li 2020,2020,1 gene,Li-2020-A Phytophthora capsici effector suppre,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17734,PHI:11105,UniProt,C9ZDB9,GenBank,CBG70277,,,87.22,txtH,,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,putative MbtH-like antibiotic biosynthesis related protein,,,thaxtomin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31282068,PubMed,10.1111/mpp.12843,Mol Plant Pathol. 2019 Oct;20(10):1379-1393,ktahlan@mun.ca,Constructed MLP mutants were reduced in virulence compared to wild-type S. scabies.,Y Li 2019,2019,3 genes,Li-2019-TxtH is a key component of the thaxtom,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17735,PHI:11106,UniProt,C9ZGA1,GenBank,CBG67542,,,87.22,SCAB_3331,,,,,,PHI:11105,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,MbtH-like protein,,,thaxtomin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31282068,PubMed,10.1111/mpp.12843,Mol Plant Pathol. 2019 Oct;20(10):1379-1393,ktahlan@mun.ca,Constructed MLP mutants were reduced in virulence compared to wild-type S. scabies.,Y Li 2019,2019,3 genes,Li-2019-TxtH is a key component of the thaxtom,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17736,PHI:11105,UniProt,C9ZDB9,GenBank,CBG70277,,,87.22,txtH,,,,,,PHI:11106,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,putative MbtH-like antibiotic biosynthesis related protein,,,thaxtomin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31282068,PubMed,10.1111/mpp.12843,Mol Plant Pathol. 2019 Oct;20(10):1379-1393,ktahlan@mun.ca,Constructed MLP mutants were reduced in virulence compared to wild-type S. scabies.,Y Li 2019,2019,3 genes,Li-2019-TxtH is a key component of the thaxtom,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17737,PHI:11107,UniProt,C9Z1K8,GenBank,CBG75491,,,87.22,SCAB_85461,,,,,,PHI:11105,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,putative MbtH homolog,,,thaxtomin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31282068,PubMed,10.1111/mpp.12843,Mol Plant Pathol. 2019 Oct;20(10):1379-1393,ktahlan@mun.ca,Constructed MLP mutants were reduced in virulence compared to wild-type S. scabies.,Y Li 2019,2019,3 genes,Li-2019-TxtH is a key component of the thaxtom,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17738,PHI:11105,UniProt,C9ZDB9,GenBank,CBG70277,,,87.22,txtH,,,,,,PHI:11107,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,putative MbtH-like antibiotic biosynthesis related protein,,,thaxtomin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31282068,PubMed,10.1111/mpp.12843,Mol Plant Pathol. 2019 Oct;20(10):1379-1393,ktahlan@mun.ca,Constructed MLP mutants were reduced in virulence compared to wild-type S. scabies.,Y Li 2019,2019,3 genes,Li-2019-TxtH is a key component of the thaxtom,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17739,PHI:11106,UniProt,C9ZGA1,GenBank,CBG67542,,,87.22,SCAB_3331,,,,,,PHI:11107; PHI:11105,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,MbtH-like protein,,,thaxtomin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31282068,PubMed,10.1111/mpp.12843,Mol Plant Pathol. 2019 Oct;20(10):1379-1393,ktahlan@mun.ca,Constructed MLP mutants were reduced in virulence compared to wild-type S. scabies.,Y Li 2019,2019,3 genes,Li-2019-TxtH is a key component of the thaxtom,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17740,PHI:11107,UniProt,C9Z1K8,GenBank,CBG75491,,,87.22,SCAB_85461,,,,,,PHI:11106; PHI:11105,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,putative MbtH homolog,,,thaxtomin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31282068,PubMed,10.1111/mpp.12843,Mol Plant Pathol. 2019 Oct;20(10):1379-1393,ktahlan@mun.ca,Constructed MLP mutants were reduced in virulence compared to wild-type S. scabies.,Y Li 2019,2019,3 genes,Li-2019-TxtH is a key component of the thaxtom,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17741,PHI:11105,UniProt,C9ZDB9,GenBank,CBG70277,,,87.22,txtH,,,,,,PHI:11106; PHI:11107,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,putative MbtH-like antibiotic biosynthesis related protein,,,thaxtomin biosynthesis,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31282068,PubMed,10.1111/mpp.12843,Mol Plant Pathol. 2019 Oct;20(10):1379-1393,ktahlan@mun.ca,Constructed MLP mutants were reduced in virulence compared to wild-type S. scabies.,Y Li 2019,2019,3 genes,Li-2019-TxtH is a key component of the thaxtom,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17742,PHI:11108,UniProt,P0A3F9,GenBank,VIRBB_AGRT9,,,C58,cagalpha (VirB11),,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,putative ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31712269,PubMed,10.1128/IAI.00790-19,Infect Immun. 2020 Jan 22;88(2):e00790-19,timothy.l.cover@vumc.org,"Mutant strains lacking Cagα, Cagβ, or CagE (putative ATPases corresponding to VirB11, VirD4, and VirB4 in prototypical T4SSs) were capable of T4SS core complex assembly but defective in CagA translocation into host cells.",A S Lin 2019,2019,3 genes,Lin-2019-Bacterial energetic requirements for,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17743,PHI:11109,UniProt,P17794,GenBank,VIRB4_AGRFC,,,C58,cagE (VirB4),,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,putative ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31712269,PubMed,10.1128/IAI.00790-19,Infect Immun. 2020 Jan 22;88(2):e00790-19,timothy.l.cover@vumc.org,"Mutant strains lacking Cagα, Cagβ, or CagE (putative ATPases corresponding to VirB11, VirD4, and VirB4 in prototypical T4SSs) were capable of T4SS core complex assembly but defective in CagA translocation into host cells.",A S Lin 2019,2019,3 genes,Lin-2019-Bacterial energetic requirements for,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17744,PHI:11110,UniProt,P18594,GenBank,VIRD4_AGRFC,,,C58,cagbeta (VirD4),,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,putative ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31712269,PubMed,10.1128/IAI.00790-19,Infect Immun. 2020 Jan 22;88(2):e00790-19,timothy.l.cover@vumc.org,"Mutant strains lacking Cagα, Cagβ, or CagE (putative ATPases corresponding to VirB11, VirD4, and VirB4 in prototypical T4SSs) were capable of T4SS core complex assembly but defective in CagA translocation into host cells.",A S Lin 2019,2019,3 genes,Lin-2019-Bacterial energetic requirements for,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17745,PHI:11111,UniProt,A0A4D6J243,GenBank,QCC87393,,,,BxATG9,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,3350,Pinus thunbergii (related: Japanese black pine),,,,leaf,autophagy protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,32187440,PubMed,10.1002/ps.5823,Pest Manag Sci. 2020 Aug;76(8):2755-2767,xqwu@njfu.edu.cn,"Inhibition of autophagy by 3-methyladenine or silencing of the autophagy genes BxATG9 and BxATG16 in PWN showed that autophagy was essential for feeding, fecundity, egg hatching and survival of PWN under oxidative stress, confirming the importance of autophagy in the antioxidant defences of PWN.",H B Liu 2020,2020,2 genes,Liu-2020-Autophagy contributes to resistance t,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17746,PHI:11112,UniProt,A0A4D6J3T5,GenBank,QCC87394,,,,BxATG16,,,,,,,6326,Bursaphelenchus xylophilus,,AMA3,pine wilt,seed plants,3350,Pinus thunbergii (related: Japanese black pine),,,,leaf,autophagy protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,32187440,PubMed,10.1002/ps.5823,Pest Manag Sci. 2020 Aug;76(8):2755-2767,xqwu@njfu.edu.cn,"Inhibition of autophagy by 3-methyladenine or silencing of the autophagy genes BxATG9 and BxATG16 in PWN showed that autophagy was essential for feeding, fecundity, egg hatching and survival of PWN under oxidative stress, confirming the importance of autophagy in the antioxidant defences of PWN.",H B Liu 2020,2020,2 genes,Liu-2020-Autophagy contributes to resistance t,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17747,PHI:11113,UniProt,A0A0H3M9Y5,GenBank,CAL71312,,,BCG Pasteur 1173P2,pknH,,,,,,,1773,Mycobacterium tuberculosis,233413,var. bovis strain AF2122/97,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; liver; kidney,probable transmembrane serine/threonine-protein kinase H,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,YVS,33347499,PubMed,10.1371/journal.ppat.1009061,PLoS Pathog. 2020 Dec 21;16(12):e1009061,naguilo@unizar.es,Evaluation of their virulence phenotype in mice revealed a reduced virulence of both M. bovis knock-in strains compared to the wild type.,E Mata 2020,2020,1 gene,Mata-2020-Independent genomic polymorphisms in,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17748,PHI:11114,UniProt,B2RM93,GenBank,BAG34488,,,ATCC 33277,rgpA,,,,,,PHI:11115; PHI:11116,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,rodents,10090,Mus musculus (related: house mouse),MC-38 cell line,,,colonic cancer cell line,arginine-specific cysteine proteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33425779,PubMed,10.3389/fcimb.2020.584798,Front Cell Infect Microbiol. 2020 Dec 23;10:584798,wangzh75@mail.sysu.edu.cn,"KDP136, a gingipain-deficient mutant of P. gingivalis 33277, showed a decreased ability to promote colorectal cancer cell proliferation.",W Mu 2020,2020,3 genes,Mu-2020-Intracellular Porphyromonas gingivalis,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17749,PHI:11115,UniProt,B2RKU0,GenBank,BAG33985,,,ATCC 33277,rgpB,,,,,,PHI:11114; PHI:11116,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,rodents,10090,Mus musculus (related: house mouse),MC-38 cell line,,,colonic cancer cell line,arginine-specific cysteine proteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33425779,PubMed,10.3389/fcimb.2020.584798,Front Cell Infect Microbiol. 2020 Dec 23;10:584798,wangzh75@mail.sysu.edu.cn,"KDP136, a gingipain-deficient mutant of P. gingivalis 33277, showed a decreased ability to promote colorectal cancer cell proliferation.",W Mu 2020,2020,3 genes,Mu-2020-Intracellular Porphyromonas gingivalis,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17750,PHI:11116,UniProt,B2RLK2,GenBank,BAG34247,,,ATCC 33277,kgp,,,,,,PHI:11114; PHI:11115,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,rodents,10090,Mus musculus (related: house mouse),MC-38 cell line,,,colonic cancer cell line,lysine-specific cysteine proteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33425779,PubMed,10.3389/fcimb.2020.584798,Front Cell Infect Microbiol. 2020 Dec 23;10:584798,wangzh75@mail.sysu.edu.cn,"KDP136, a gingipain-deficient mutant of P. gingivalis 33277, showed a decreased ability to promote colorectal cancer cell proliferation.",W Mu 2020,2020,3 genes,Mu-2020-Intracellular Porphyromonas gingivalis,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17751,PHI:11114,UniProt,B2RM93,GenBank,BAG34488,,,ATCC 33277,rgpA,,,,,,PHI:11115; PHI:11116,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),S1 cell line,,,colonic cancer cell line,arginine-specific cysteine proteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33425779,PubMed,10.3389/fcimb.2020.584798,Front Cell Infect Microbiol. 2020 Dec 23;10:584798,wangzh75@mail.sysu.edu.cn,"KDP136, a gingipain-deficient mutant of P. gingivalis 33277, showed a decreased ability to promote colorectal cancer cell proliferation.",W Mu 2020,2020,3 genes,Mu-2020-Intracellular Porphyromonas gingivalis,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17752,PHI:11115,UniProt,B2RKU0,GenBank,BAG33985,,,ATCC 33277,rgpB,,,,,,PHI:11114; PHI:11116,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),S1 cell line,,,colonic cancer cell line,arginine-specific cysteine proteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33425779,PubMed,10.3389/fcimb.2020.584798,Front Cell Infect Microbiol. 2020 Dec 23;10:584798,wangzh75@mail.sysu.edu.cn,"KDP136, a gingipain-deficient mutant of P. gingivalis 33277, showed a decreased ability to promote colorectal cancer cell proliferation.",W Mu 2020,2020,3 genes,Mu-2020-Intracellular Porphyromonas gingivalis,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17753,PHI:11116,UniProt,B2RLK2,GenBank,BAG34247,,,ATCC 33277,kgp,,,,,,PHI:11114; PHI:11115,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),S1 cell line,,,colonic cancer cell line,lysine-specific cysteine proteinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33425779,PubMed,10.3389/fcimb.2020.584798,Front Cell Infect Microbiol. 2020 Dec 23;10:584798,wangzh75@mail.sysu.edu.cn,"KDP136, a gingipain-deficient mutant of P. gingivalis 33277, showed a decreased ability to promote colorectal cancer cell proliferation.",W Mu 2020,2020,3 genes,Mu-2020-Intracellular Porphyromonas gingivalis,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17754,PHI:11117,UniProt,A0A0D2Y5F9,GenBank,KNB11716,,,4287,noxR,chromosome 10,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,root,oxidoreductase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31364172,PubMed,10.1111/nph.16085,New Phytol. 2019 Dec;224(4):1600-1612,ge2dipia@uco.es,"NoxA and NoxB have minor independent roles in pathogenicity of F.oxysporum on tomato plants, with NoxB contributing specifically to invasive growth.",D E Nordzieke 2019,2019,3 genes,Nordzieke-2019-NADPH oxidase regulates chemotr,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17755,PHI:11118,UniProt,A0A420RYE1,GenBank,RKL22056,,,Fo_PG,noxA,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,root,superoxide-generating NADPH oxidase heavy chain subunit A,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31364172,PubMed,10.1111/nph.16085,New Phytol. 2019 Dec;224(4):1600-1612,ge2dipia@uco.es,"NoxA and NoxB have minor independent roles in pathogenicity of F.oxysporum on tomato plants, with NoxB contributing specifically to invasive growth.",D E Nordzieke 2019,2019,3 genes,Nordzieke-2019-NADPH oxidase regulates chemotr,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17756,PHI:11119,,no data found,,,,,,noxB,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,root,NADPH oxidase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31364172,PubMed,10.1111/nph.16085,New Phytol. 2019 Dec;224(4):1600-1612,ge2dipia@uco.es,"NoxA and NoxB have minor independent roles in pathogenicity of F.oxysporum on tomato plants, with NoxB contributing specifically to invasive growth.",D E Nordzieke 2019,2019,3 genes,Nordzieke-2019-NADPH oxidase regulates chemotr,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17757,PHI:11120,UniProt,Q7VTC1,GenBank,CAE43883,,,Tohama I,rplN,,single G-to-T nucleotide transversion in the 59-untranslated region (59-UTR) of the rplN,,,,,520,Bordetella pertussis,257313,Tohama I,pertussis,primates,9606,Homo sapiens (related: human),,,,macrophage,50S ribosomal protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33293402,PubMed,10.1128/mSystems.00612-20,mSystems. 2020 Dec 8;5(6):e00612-20,sebo@biomed.cas.cz,The mutant survived like the parental bacteria for >2 weeks inside infected primary human macrophages and persisted within infected mouse lungs for a longer period than wild-type B. pertussis.,J Novak 2020,2020,1 gene,Novák-2020-A Mutation Upstream of the rplN-rps,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17758,PHI:11120,UniProt,Q7VTC1,GenBank,CAE43883,,,Tohama I,rplN,,single G-to-T nucleotide transversion in the 59-untranslated region (59-UTR) of the rplN,,,,,520,Bordetella pertussis,257313,Tohama I,pertussis,rodents,10090,Mus musculus (related: house mouse),BALB/cByJ,,,lung,50S ribosomal protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33293402,PubMed,10.1128/mSystems.00612-20,mSystems. 2020 Dec 8;5(6):e00612-20,sebo@biomed.cas.cz,The mutant survived like the parental bacteria for >2 weeks inside infected primary human macrophages and persisted within infected mouse lungs for a longer period than wild-type B. pertussis.,J Novak 2020,2020,1 gene,Novák-2020-A Mutation Upstream of the rplN-rps,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17759,PHI:11121,UniProt,A0A0D2XVA4,GenBank,KNB05730,,,4287,pct6 (FOXG_07912),chromosome 4,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,root,PPM-type phosphatase domain-containing protein,,,,reduced virulence,,,,,,,,wild type,reduced,no,sorbitol; KCl; sodium dodecyl sulphate (SDS); calcofluor white; menadione; fludioxonil,sorbitol: CHEBI:30911; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; calcofluor white: CHEBI:50011; menadione: CHEBI:28869; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,31802599,PubMed,10.1111/mpp.12889,Mol Plant Pathol. 2020 Feb;21(2):206-217,ge1hedic@uco.es,Targeted inactivation of ptc6 entailed enhanced susceptibility to cell wall stresses caused by Calcofluor White and reduced the invasive growth and virulence of F. oxysporum.,J C Nunez-Rodriguez 2019,2019,1 gene,Nunez-Rodriguez-2019-The phosphatase Ptc6 is i,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17760,PHI:11122,UniProt,no data found,GenBank,QEE55921,,,ATCC BAA-1790,mlaF,,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,phospholipid ABC transporter ATP-binding protein,,,isoprenoid biosynthesis,reduced virulence,,,,,,,,,,no,SDS; EDTA; gentamicin; erythromycin; meropenem; carbenicillin; paraquat,SDS: CHEBI:8984; EDTA: CHEBI:64758; gentamicin: CHEBI:17833; erythromycin: CHEBI:48923; meropenem: CHEBI:43968; carbenicillin: CHEBI:3393; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,32905776,PubMed,10.1016/j.celrep.2020.108129,Cell Rep. 2020 Sep 8;32(10):108129,eric.skaar@vumc.org,Deletion of mlaF of the maintenance of lipid asymmetry (Mla) system caused A. baumannii to become more susceptible to pulmonary surfactants and antibiotics and decreased bacterial survival in the lungs of mice.,L D Palmer 2020,2020,1 gene,Palmer-2020-Modulating Isoprenoid Biosynthesis,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17761,PHI:11123,,no data found,,,,,,rprA,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,Hfq-dependent small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33314618,PubMed,10.1111/mpp.13024,Mol Plant Pathol. 2021 Feb;22(2):255-270,sundin@msu.edu,Amylovoran production was significantly reduced in the Ea1189ΔrprA mutant.,J Peng 2020,2020,1 gene,Peng-2021-Orchestration of virulence factor ex,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17762,PHI:11123,,no data found,,,,,,rprA,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,Hfq-dependent small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33314618,PubMed,10.1111/mpp.13024,Mol Plant Pathol. 2021 Feb;22(2):255-270,sundin@msu.edu,"The Ea1189ΔrprA mutant exhibited a minimal HR on Nicotiana benthamiana leaves, suggesting a positive effect of RprA on the function of T3SS.",J Peng 2020,2020,1 gene,Peng-2021-Orchestration of virulence factor ex,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17763,PHI:11124,UniProt,I6Y461,GenBank,CCP43332,,,H37Rv,mce2E (Rv0593),,,,,,,1773,Mycobacterium tuberculosis,33892,var. bovis strain BCG,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; liver,possible Mce-family lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29572547,PubMed,10.1038/s41423-018-0016-0,Cell Mol Immunol. 2019 Apr;16(4):380-391,liucuihua@im.ac.cn,Mce2E inhibited the activation of the ERK and JNK MAPK signaling pathways to suppress the macrophage innate immune response.,L Qiang 2020,2020,1 gene,Qiang-2018-Mycobacterium tuberculosis Mce2E su,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17764,PHI:11124,UniProt,I6Y461,GenBank,CCP43332,,,H37Rv,mce2E (Rv0593),,,,,,,1773,Mycobacterium tuberculosis,33892,var. bovis strain BCG,tuberculosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,possible Mce-family lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29572547,PubMed,10.1038/s41423-018-0016-0,Cell Mol Immunol. 2019 Apr;16(4):380-391,liucuihua@im.ac.cn,Mce2E inhibited the activation of the ERK and JNK MAPK signaling pathways to suppress the macrophage innate immune response.,L Qiang 2020,2020,1 gene,Qiang-2018-Mycobacterium tuberculosis Mce2E su,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17765,PHI:11124,UniProt,I6Y461,GenBank,CCP43332,,,H37Rv,mce2E (Rv0593),,,,,,,1773,Mycobacterium tuberculosis,33892,var. bovis strain BCG,tuberculosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,possible Mce-family lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29572547,PubMed,10.1038/s41423-018-0016-0,Cell Mol Immunol. 2019 Apr;16(4):380-391,liucuihua@im.ac.cn,Mce2E blocked K48-linked polyubiquitination of eEF1A1 to promote epithelial cell proliferation.,L Qiang 2020,2020,1 gene,Qiang-2018-Mycobacterium tuberculosis Mce2E su,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17766,PHI:11125,,no data found,,,,,,sRNA-17,,,,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,small RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33329434,PubMed,10.3389/fmicb.2020.574833,Front Microbiol. 2020 Nov 23;11:574833,fenglu63@nankai.edu.cn,Deletion of sRNA-17 enhanced Escherichia coli K1 survival in blood and meningitis invivo,H Sun 2020,2020,1 gene,Sun-2020-An ArcA-Modulated Small RNA in Pathog,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17767,PHI:11126,UniProt,P21454,GenBank,CAA78760,,,TML R66,spvB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,intestinal epithelium,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33392110,PubMed,10.3389/fcimb.2020.606541,Front Cell Infect Microbiol. 2020 Dec 17;10:606541,wushuyan@suda.edu.cn,"SpvB enhanced bacterial pathogenicity during S. typhimurium infection in vivo, and contributed to intestinal epithelial barrier dysfunction in both infection systems.",L Sun 2020,2020,1 gene,Sun-2020-Salmonella Effector SpvB Disrupts Int,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17768,PHI:11126,UniProt,P21454,GenBank,CAA78760,,,TML R66,spvB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33392110,PubMed,10.3389/fcimb.2020.606541,Front Cell Infect Microbiol. 2020 Dec 17;10:606541,wushuyan@suda.edu.cn,"SpvB enhanced bacterial pathogenicity during S. typhimurium infection in vivo, and contributed to intestinal epithelial barrier dysfunction in both infection systems.",L Sun 2020,2020,1 gene,Sun-2020-Salmonella Effector SpvB Disrupts Int,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17769,PHI:11127,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; kidney; spleen; alveolar macrophage,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33436835,PubMed,10.1038/s41598-020-79966-9,Sci Rep. 2021 Jan 12;11(1):618,tan.man-wah@gene.com,OmpA was necessary and sufficient to cause mitochondrial fragmentation.,V Tiku 2021,2021,1 gene,Tiku-2021-Outer membrane vesicles containing O,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17770,PHI:11127,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33436835,PubMed,10.1038/s41598-020-79966-9,Sci Rep. 2021 Jan 12;11(1):618,tan.man-wah@gene.com,OmpA was necessary and sufficient to cause mitochondrial fragmentation.,V Tiku 2021,2021,1 gene,Tiku-2021-Outer membrane vesicles containing O,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17771,PHI:11127,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33436835,PubMed,10.1038/s41598-020-79966-9,Sci Rep. 2021 Jan 12;11(1):618,tan.man-wah@gene.com,OmpA was necessary and sufficient to cause mitochondrial fragmentation.,V Tiku 2021,2021,1 gene,Tiku-2021-Outer membrane vesicles containing O,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17772,PHI:11127,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33436835,PubMed,10.1038/s41598-020-79966-9,Sci Rep. 2021 Jan 12;11(1):618,tan.man-wah@gene.com,OmpA was necessary and sufficient to cause mitochondrial fragmentation.,V Tiku 2021,2021,1 gene,Tiku-2021-Outer membrane vesicles containing O,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17773,PHI:11128,UniProt,G2WVW3,GenBank,EGY19733,,,VdLs.17,hex1 (VDAG_01749),chromosome 7,,,,,,27337,Verticillium dahliae,1202531,VdLs.17,vascular wilt,eudicots,4111,Solanum melongena (related: eggplant),cv. Black Beauty,,,leaf,woronin body major protein,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,NaCl; sorbitol; calcofluor white; Congo red; SDS; fluconazole; cymoxanil; fosetyl-AI; mandipropamid; cyflufenamid; H2O2; paraquat; farnesol; iprodione; N-acetyl cysteine,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984; fluconazole: CHEBI:46081; cymoxanil: CHEBI:81788; fosetyl-AI: CHEBI:84033; mandipropamid: CHEBI:81802; cyflufenamid: CHEBI:81797; H2O2: CHEBI:16240; paraquat: CHEBI:34905; farnesol: CHEBI:28600; iprodione: CHEBI:28909; N-acetyl cysteine: CHEBI:28939; amphotericin B: CHEBI:2682,,,,,gene deletion: full; gene complementation,,,YVS,33297524,PubMed,10.3390/jof6040344,J Fungi (Basel). 2020 Dec 7;6(4):344,matypas@biol.uoa.gr,"Hex1 was required both for normal responses to osmotic stress and factors that affect the cell wall and plasma-membrane integrity, and for normal resistance to oxidative stress and reactive oxygen species (ROS) homeostasis.",V Vangalis 2020,2020,1 gene,"Vangalis-2020-Hex1, the Major Component of Wor",BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17774,PHI:11129,UniProt,E9EZ82,GenBank,EFY99273,,,ARSEF 23,MrPEX33 (MAA_05331),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"peroxisomal membrane anchor domain-containing protein, variant 2",,,,reduced virulence,,yes,yes,,,reduced,,reduced,reduced,no,CR; CFW; SDS; menadione; H2O2; NaCl; sorbitol,CR: CHEBI:34653; CFW: CHEBI:50011; SDS: CHEBI:8984; menadione: CHEBI:28869; H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,33443633,PubMed,10.1007/s00253-020-11071-3,Appl Microbiol Biotechnol. 2021 Feb;105(3):1079-1090,bhuang@ahau.edu.cn,ΔMrPEX33 mutants showed a significant decrease in tolerance to cell wall integrity and oxidative stress.,Z Wang 2021,2021,1 gene,Wang-2021-MrPEX33 is involved in infection-rel,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17775,PHI:11130,UniProt,A8VPA2,GenBank,ABW24640,,,C10-1,pORF5,,,,,,,813,Chlamydia trachomatis,,,urinary tract infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,plasmid protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33391210,PubMed,10.3389/fmicb.2020.593295,Front Microbiol. 2020 Dec 17;11:593295,lzhy1023@hotmail.com,Inhibition of ZFAS1 reduced the anti-apoptotic effect of pORF5 and the infectivity of C. trachomatis.,Y Wen 2020,2020,1 gene,Wen-2020-Chlamydia trachomatis Plasmid Protein,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17776,PHI:11131,UniProt,S4E4Q5,GenBank,EPH95667,,,13-SD-W-01,WalR,,,,,,,1351,Enterococcus faecalis,226185,V583,periapical periodontitis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,mandible,transcriptional regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33365069,PubMed,10.3892/etm.2020.9501,Exp Ther Med. 2021 Jan;21(1):69,caesarzh@163.com,Antisense walR RNA that led to a reduction in biofilm formation and the pathogenicity of E. faecalis.,S Wu 2021,2021,1 gene,Wu-2021-Endogenous antisense walR RNA modulate,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17777,PHI:11132,UniProt,A0A2P2HLV9,GenBank,KOC15600,,,AF70,fab1,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,phosphatidylinositol-3-phosphate-5-kinase,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33315533,PubMed,10.1080/21505594.2020.1859820,Virulence. 2021 Dec;12(1):96-113,wshyyl@sina.com,"Loss of fab1 function was found to affect the growth, conidia and sclerotial development, cellular acidification and metal ion homeostasis, aflatoxin production and pathogenicity of A. flavus.",M Yang 2021,2021,1 gene,Yang-2021-A novel phosphoinositide kinase Fab1,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17778,PHI:11132,UniProt,A0A2P2HLV9,GenBank,KOC15600,,,AF70,fab1,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,phosphatidylinositol-3-phosphate-5-kinase,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33315533,PubMed,10.1080/21505594.2020.1859820,Virulence. 2021 Dec;12(1):96-113,wshyyl@sina.com,"Loss of fab1 function was found to affect the growth, conidia and sclerotial development, cellular acidification and metal ion homeostasis, aflatoxin production and pathogenicity of A. flavus.",M Yang 2021,2021,1 gene,Yang-2021-A novel phosphoinositide kinase Fab1,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17779,PHI:11133,UniProt,A0A0H3NKG5,GenBank,CBW20280,,,SL1344,SiiA,,SiiA-R120A and SiiA-S197E,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain MvP771,gastroenteritis,carnivores,9612,Canis lupus (related: gray wolf),subsp. familiaris MDCK cell line,,,MDCK cell,type I secretion-related protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31419359,PubMed,10.1111/mmi.14368,Mol Microbiol. 2019 Nov;112(5):1403-1422,yves.muller@fau.de,Mutation of Arg162 impeded PG binding of SiiA and reduced Salmonella invasion efficacy.,P Kirchweger 2019,2019,1 gene,Kirchweger-2019-Structural and functional char,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17780,PHI:11133,UniProt,A0A0H3NKG5,GenBank,CBW20280,,,SL1344,SiiA,,SiiA-R162A,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain MvP771,gastroenteritis,carnivores,9612,Canis lupus (related: gray wolf),subsp. familiaris MDCK cell line,,,MDCK cell,type I secretion-related protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31419359,PubMed,10.1111/mmi.14368,Mol Microbiol. 2019 Nov;112(5):1403-1422,yves.muller@fau.de,Mutation of Arg162 impeded PG binding of SiiA and reduced Salmonella invasion efficacy.,P Kirchweger 2019,2019,1 gene,Kirchweger-2019-Structural and functional char,BATCH_104B,2021-02-01,MC,,,,,,,,,,,,,
,,Record 17781,PHI:11134,UniProt,Q8PRG7,GenBank,AAM39311,,,306,PthA4 (XACb0065),,pthA4:Tn5,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33465093,PubMed,10.1371/journal.pgen.1009310. eCollection 2021 Jan,PLoS Genet. 2021 Jan 19;17(1):e1009310,nianwang@ufl.edu,Introduction of dTALEWTLOB1 or the adapted TALEs to Xcc pthA4:Tn5 significantly improved bacterial colonization of sweet orange leaves.,D Teper 2021,2021,1 gene,Teper-2021-Consequences of adaptation of TAL e,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17782,PHI:11135,UniProt,Q59QT2,GenBank,AOW29752,,,SC5314,ARP1 (orf19.2641),chromosome 5,,,,,,5476,Candida albicans,,SN148,oropharyngeal candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,liver; spleen; kidney,putative actin-related protein 1,,,,reduced virulence,,,,,,,,aberrant,,no,CFW; Congo red; H2O2; rapamycin; fluconazole,"calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2,  rapamycin: CHEBI:9168; fluconazole: CHEBI:46081",,,,,gene deletion: full; gene complementation,,,YVS,33363697,PubMed,10.1016/j.csbj.2020.11.034. eCollection 2020,Comput Struct Biotechnol J. 2020 Dec 1;18:4002-4015,jinrong532@ntu.edu.cn,"The loss of ARP1 activated filamentous and invasive growth in vitro, and that it positively regulated virulence in vivo.",S Yao 2020,2020,1 gene,"Yao-2020-Loss of Arp1, a putative actin-relate",BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17783,PHI:11136,UniProt,P0A2M9,GenBank,AAL23529,,,LT2,spvC,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,typhoid,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; cecum,Salmonella plasmid virulence C protein; MAPK phosphothreonine lyase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33384666,PubMed,10.3389/fmicb.2020.562491,Front Microbiol. 2020 Dec 15;11:562491,wushuyan@suda.edu.cn,"SpvC attenuated intestinal inflammation, suppressed pyroptosis through phosphothreonine lyase activity, and reduced pyroptosis in the ceca.",L Zuo 2020,2020,1 gene,Zuo-2020-Salmonella spvC Gene Inhibits Pyropto,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17784,PHI:11137,UniProt,Q6FMU4,GenBank,CAG61411,,,CBS 138,ath1 (CAGL0K05137g),chromosome K,,,,,,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,duodenum; ileum; cecum; right colon; left colon; tongue; kidney,trehalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17785,PHI:11138,UniProt,Q6FIZ3,GenBank,CAG62779,,,CBS 138,nth1 (CAGL0M10439g),chromosome M,,,,,,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,duodenum; ileum; cecum; right colon; left colon; tongue; kidney,trehalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17786,PHI:11139,UniProt,Q6FWN0,GenBank,CAG58270,,,CBS 138,nth2 (CAGL0C04323g),chromosome C,,,,,,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,duodenum; ileum; cecum; right colon; left colon; tongue; kidney,trehalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17787,PHI:11137,UniProt,Q6FMU4,GenBank,CAG61411,,,CBS 138,ath1 (CAGL0K05137g),chromosome K,,,,,PHI:11138; PHI:11139,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,duodenum; ileum; cecum; right colon; left colon; tongue; kidney,trehalase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17788,PHI:11138,UniProt,Q6FIZ3,GenBank,CAG62779,,,CBS 138,nth1 (CAGL0M10439g),chromosome M,,,,,PHI:11137; PHI:11139,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,duodenum; ileum; cecum; right colon; left colon; tongue; kidney,trehalase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17789,PHI:11139,UniProt,Q6FWN0,GenBank,CAG58270,,,CBS 138,nth2 (CAGL0C04323g),chromosome C,,,,,PHI:11137; PHI:11138,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,duodenum; ileum; cecum; right colon; left colon; tongue; kidney,trehalase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17790,PHI:11137,UniProt,Q6FMU4,GenBank,CAG61411,,,CBS 138,ath1 (CAGL0K05137g),chromosome K,,,,,,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,trehalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17791,PHI:11138,UniProt,Q6FIZ3,GenBank,CAG62779,,,CBS 138,nth1 (CAGL0M10439g),chromosome M,,,,,,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,trehalase,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17792,PHI:11139,UniProt,Q6FWN0,GenBank,CAG58270,,,CBS 138,nth2 (CAGL0C04323g),chromosome C,,,,,,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,trehalase,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17793,PHI:11137,UniProt,Q6FMU4,GenBank,CAG61411,,,CBS 138,ath1 (CAGL0K05137g),chromosome K,,,,,PHI:11138; PHI:11139,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,trehalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17794,PHI:11138,UniProt,Q6FIZ3,GenBank,CAG62779,,,CBS 138,nth1 (CAGL0M10439g),chromosome M,,,,,PHI:11137; PHI:11139,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,trehalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17795,PHI:11139,UniProt,Q6FWN0,GenBank,CAG58270,,,CBS 138,nth2 (CAGL0C04323g),chromosome C,,,,,PHI:11137; PHI:11138,5478,Candida glabrata,,311,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,trehalase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17796,PHI:11137,UniProt,Q6FMU4,GenBank,CAG61411,,,CBS 138,ath1 (CAGL0K05137g),chromosome K,,,,,,5478,Candida glabrata,,311,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,macrophage,trehalase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17797,PHI:11138,UniProt,Q6FIZ3,GenBank,CAG62779,,,CBS 138,nth1 (CAGL0M10439g),chromosome M,,,,,,5478,Candida glabrata,,311,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,macrophage,trehalase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17798,PHI:11139,UniProt,Q6FWN0,GenBank,CAG58270,,,CBS 138,nth2 (CAGL0C04323g),chromosome C,,,,,,5478,Candida glabrata,,311,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,macrophage,trehalase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17799,PHI:11137,UniProt,Q6FMU4,GenBank,CAG61411,,,CBS 138,ath1 (CAGL0K05137g),chromosome K,,,,,PHI:11138; PHI:11139,5478,Candida glabrata,,311,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,macrophage,trehalase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17800,PHI:11138,UniProt,Q6FIZ3,GenBank,CAG62779,,,CBS 138,nth1 (CAGL0M10439g),chromosome M,,,,,PHI:11137; PHI:11139,5478,Candida glabrata,,311,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,macrophage,trehalase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17801,PHI:11139,UniProt,Q6FWN0,GenBank,CAG58270,,,CBS 138,nth2 (CAGL0C04323g),chromosome C,,,,,PHI:11137; PHI:11138,5478,Candida glabrata,,311,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,macrophage,trehalase,,,,reduced virulence,,,,,,,,,,no,H2O2; NaCl; calcofluor white,H2O2: CHEBI:16240; NaCl: CHEBI:26710; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33356857,PubMed,10.1080/21505594.2020.1868825,Virulence. 2021 Dec;12(1):329-345,patrick.vandijck@kuleuven.vib.be,The triple deletion strain was unable to establish a stable colonization of the gastrointestinal (GI) tract in mice indicating the importance of having trehalase activity for colonization in the gut.,M Van Ende 2021,2021,3 genes,Van Ende-2021-The involvement of the Candida g,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17802,PHI:11140,UniProt,G4MYS1,GenBank,EHA55300,,,70-15,MGG_08144 (MoYpt7),chromosome 2,dominant negative (DN) form of MoYpt7 (N125I mutation),,MGG_05089 (MoVps35),UniProt: G4N4D6; GenBank: EHA52804,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Ras-like protein Rab7,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene mutation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17803,PHI:11140,UniProt,G4MYS1,GenBank,EHA55300,,,70-15,MGG_08144 (MoYpt7),chromosome 2,constitutively active (CA) form of MoYpt7 (Q67L mutation),,MGG_05089 (MoVps35),UniProt: G4N4D6; GenBank: EHA52804,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Ras-like protein Rab7,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17804,PHI:11140,UniProt,G4MYS1,GenBank,EHA55300,,,70-15,MGG_08144 (MoYpt7),chromosome 2,,,MGG_05089 (MoVps35),UniProt: G4N4D6; GenBank: EHA52804,PHI:11141,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Ras-like protein Rab7,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17805,PHI:11141,UniProt,G4N4D6,GenBank,EHA52804,,,70-15,MGG_05089 (MoVps35),chromosome 3,,,MGG_08144 (MoYpt7),UniProt: G4MYS1; GenBank: EHA55300,PHI:11140,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,vacuolar protein sorting associated protein 35,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17806,PHI:11140,UniProt,G4MYS1,GenBank,EHA55300,,,70-15,MGG_08144 (MoYpt7),chromosome 2,,,MGG_05089 (MoVps35),UniProt: G4N4D6; GenBank: EHA52804,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Ras-like protein Rab7,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17807,PHI:11142,UniProt,G4MZL7,GenBank,EHA54576,,,70-15,MoVps17,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,vacuolar protein sorting associated protein 17,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17808,PHI:11141,UniProt,G4N4D6,GenBank,EHA52804,,,70-15,MGG_05089 (MoVps35),chromosome 3,,,MGG_08144 (MoYpt7),UniProt: G4MYS1; GenBank: EHA55300,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,vacuolar protein sorting associated protein 35,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17809,PHI:11143,UniProt,G4MU71,GenBank,EHA53952,,,70-15,MGG_04830 (MoVps26),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,vacuolar protein sorting-associated protein 26B-B,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17810,PHI:11144,UniProt,G4MKD1,GenBank,EHA56722,,,70-15,MGG_02524 (MoVps29),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,vacuolar protein sorting associated protein 29,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17811,PHI:11140,UniProt,G4MYS1,GenBank,EHA55300,,,70-15,MGG_08144 (MoYpt7),chromosome 2,dominant negative (DN) form of MoYpt7 (N125I mutation),,MGG_05089 (MoVps35),UniProt: G4N4D6; GenBank: EHA52804,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,Ras-like protein Rab7,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene mutation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17812,PHI:11140,UniProt,G4MYS1,GenBank,EHA55300,,,70-15,MGG_08144 (MoYpt7),chromosome 2,constitutively active (CA) form of MoYpt7 (Q67L mutation),,MGG_05089 (MoVps35),UniProt: G4N4D6; GenBank: EHA52804,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,Ras-like protein Rab7,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene mutation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17813,PHI:11140,UniProt,G4MYS1,GenBank,EHA55300,,,70-15,MGG_08144 (MoYpt7),chromosome 2,,,MGG_05089 (MoVps35),UniProt: G4N4D6; GenBank: EHA52804,PHI:11141,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,Ras-like protein Rab7,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17814,PHI:11141,UniProt,G4N4D6,GenBank,EHA52804,,,70-15,MGG_05089 (MoVps35),chromosome 3,,,MGG_08144 (MoYpt7),UniProt: G4MYS1; GenBank: EHA55300,PHI:11140,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,vacuolar protein sorting associated protein 35,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17815,PHI:11140,UniProt,G4MYS1,GenBank,EHA55300,,,70-15,MGG_08144 (MoYpt7),chromosome 2,,,MGG_05089 (MoVps35),UniProt: G4N4D6; GenBank: EHA52804,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,Ras-like protein Rab7,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17816,PHI:11142,UniProt,G4MZL7,GenBank,EHA54576,,,70-15,MoVps17,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,vacuolar protein sorting associated protein 17,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17817,PHI:11141,UniProt,G4N4D6,GenBank,EHA52804,,,70-15,MGG_05089 (MoVps35),chromosome 3,,,MGG_08144 (MoYpt7),UniProt: G4MYS1; GenBank: EHA55300,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,vacuolar protein sorting associated protein 35,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17818,PHI:11143,UniProt,G4MU71,GenBank,EHA53952,,,70-15,MGG_04830 (MoVps26),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,vacuolar protein sorting-associated protein 26B-B,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17819,PHI:11144,UniProt,G4MKD1,GenBank,EHA56722,,,70-15,MGG_02524 (MoVps29),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,vacuolar protein sorting associated protein 29,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33350057,PubMed,10.1111/mpp.13029. Epub 2020 Dec 21,Mol Plant Pathol. 2021 Feb;22(2):284-298,wenhuiz@fafu.edu.cn,"MoYpt7 and all the retromer complex subunits were necessary for pathogenicity of M. oryzae, and that ΔMoypt7 and ΔMovps17 mutants appeared less pathogenic than the mutants of the retromer CSC subunits.",C Wu 2021,2021,5 genes,Wu-2021-The retromer CSC subcomplex is recruit,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17820,PHI:11145,UniProt,I1S1C8,GenBank,CEF75972,,,PH-1,FgStu2 (FGSG_10528),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Huaimai 33,,,leaf,Dis1/Stu2/XMAP215 family protein,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced; aberrant,,no,carbendazim,carbendazim: CHEBI:3392,,,,,promoter mutation,,,YVS,33329417,PubMed,10.3389/fmicb.2020.545015,Front Microbiol. 2020 Nov 20;11:545015,mgzhou@njau.edu.cn,"The FgStu2-Si mutants exhibited curved conidia, decreased number of conidial production, blocked ability of perithecia production, decreased pathogenicity and deoxynivalenol (DON) production.",Y Zhu 2020,2020,1 gene,Zhu-2020-The Dis1_Stu2_XMAP215 Family Gene FgS,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17821,PHI:11146,UniProt,I1RCM1,GenBank,CEF73459,,,PH-1,Fg01341,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Yangmai 158,,,spike,calcineurin-responsive transcription factor,,,,reduced virulence,,,,,,reduced; aberrant,wild type,reduced; aberrant,,no,tebuconazole; carbendazim; phenamacril; fludioxonil,tebuconazole: CHEBI:81781; carbendazim: CHEBI:3392; phenamacril: CAS:3336-69-4; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,33324378,PubMed,10.3389/fmicb.2020.597998,Front Microbiol. 2020 Nov 26;11:597998,huaigu@jaas.ac.cn,The virulence of the ΔFg01341 mutant in flowering wheat heads and corn silks dramatically decreased with the reduction in deoxynivalenol production.,X Zhang 2020,2020,2 genes,Zhang-2020-Functional Characterization of Calc,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17822,PHI:11147,UniProt,I1RCM9,GenBank,CEF73469,,,PH-1,Fg01350,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Yangmai 158,,,spike,calcineurin-responsive transcription factor,,,,reduced virulence,,,,,,reduced; aberrant,wild type,reduced; aberrant,,no,tebuconazole; carbendazim; phenamacril; fludioxonil,tebuconazole: CHEBI:81781; carbendazim: CHEBI:3392; phenamacril: CAS:3336-69-4; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,33324378,PubMed,10.3389/fmicb.2020.597998,Front Microbiol. 2020 Nov 26;11:597998,huaigu@jaas.ac.cn,"ΔFg01350 showed defects in hyphal growth, sexual production, virulence, and deoxynivalenol production.",X Zhang 2020,2020,2 genes,Zhang-2020-Functional Characterization of Calc,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17823,PHI:11146,UniProt,I1RCM1,GenBank,CEF73459,,,PH-1,Fg01341,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,kernel,calcineurin-responsive transcription factor,,,,reduced virulence,,,,,,reduced; aberrant,wild type,reduced; aberrant,,no,tebuconazole; carbendazim; phenamacril; fludioxonil,tebuconazole: CHEBI:81781; carbendazim: CHEBI:3392; phenamacril: CAS:3336-69-4; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,33324378,PubMed,10.3389/fmicb.2020.597998,Front Microbiol. 2020 Nov 26;11:597998,huaigu@jaas.ac.cn,The virulence of the ΔFg01341 mutant in flowering wheat heads and corn silks dramatically decreased with the reduction in deoxynivalenol production.,X Zhang 2020,2020,2 genes,Zhang-2020-Functional Characterization of Calc,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17824,PHI:11147,UniProt,I1RCM9,GenBank,CEF73469,,,PH-1,Fg01350,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,kernel,calcineurin-responsive transcription factor,,,,reduced virulence,,,,,,reduced; aberrant,wild type,reduced; aberrant,,no,tebuconazole; carbendazim; phenamacril; fludioxonil,tebuconazole: CHEBI:81781; carbendazim: CHEBI:3392; phenamacril: CAS:3336-69-4; fludioxonil: CAS:131341-86-1,,,,,gene deletion: full; gene complementation,,,YVS,33324378,PubMed,10.3389/fmicb.2020.597998,Front Microbiol. 2020 Nov 26;11:597998,huaigu@jaas.ac.cn,"ΔFg01350 showed defects in hyphal growth, sexual production, virulence, and deoxynivalenol production.",X Zhang 2020,2020,2 genes,Zhang-2020-Functional Characterization of Calc,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17825,PHI:11148,UniProt,G1XHM0,GenBank,EGX47408,,,ATCC 24927,Aolatg4,,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,autophagy related protein,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,sorbitol; Congo red; menadione,sorbitol: CHEBI:30911; Congo red: CHEBI:34653; menadione: CHEBI:28869,,,,,gene deletion: full,,,YVS,33304340,PubMed,10.3389/fmicb.2020.592524,Front Microbiol. 2020 Nov 16;11:592524,jinkui960@ynu.edu.cn,Autophagosome formation and the autophagic process were impaired in the ΔAolatg4 mutant.Species name 'Arthrobotrys oligospora' and Taxid '13349' merged into 'Orbilia oligospora' Taxid '2813651' by NCBI on Feb 19 2021.,D Zhou 2020,2020,1 gene,Zhou-2020-The Autophagy-Related Gene Aolatg4 R,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17826,PHI:11149,UniProt,Q6D4B5,GenBank,CAG75378,,,SCRI1043,eda,,,,,,,29471,Pectobacterium atrosepticum,,SCRI1039,soft rot (potato); blackleg disease (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,2-keto-3-deoxy-6-phosphogluconate aldolase,,,entner-Doudoroff (ED) pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33301200,PubMed,10.1111/mpp.13025,Mol Plant Pathol. 2021 Feb;22(2):271-283,ian.toth@hutton.ac.uk,ΔEda exhibited significant decreased virulence on potato tubers and colonization in planta and was greatly attenuated in pectinase activity and the ability to use pectin breakdown products.,H Wang 2021,2021,2 genes,Wang-2021-Pectobacterium atrosepticum KDPG ald,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17827,PHI:11150,UniProt,Q6D652,GenBank,CAG74739,,,SCRI1043,edd,,,,,,,29471,Pectobacterium atrosepticum,,SCRI1039,soft rot (potato); blackleg disease (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,phosphogluconate dehydratase,,,entner-Doudoroff (ED) pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33301200,PubMed,10.1111/mpp.13025,Mol Plant Pathol. 2021 Feb;22(2):271-283,ian.toth@hutton.ac.uk,ΔEda exhibited significant decreased virulence on potato tubers and colonization in planta and was greatly attenuated in pectinase activity and the ability to use pectin breakdown products.,H Wang 2021,2021,2 genes,Wang-2021-Pectobacterium atrosepticum KDPG ald,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17828,PHI:11151,UniProt,A0A0D6IDM0,GenBank,AKH08767,,,YU39,hcp1,,,,hcp2; hcp3,UniProt: H9L4I8; GenBank: AKH05884; UniProt: no data found; GenBank: no data found,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,hemolysin-coregulated protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33300449,PubMed,10.1080/21505594.2020.1854538,Virulence. 2020 Dec;11(1):1716-1726,lilei@hsc.pku.edu.cn,All the mutants showed an internalization level similar to that of the wild type 14028s.,P Wang 2020,2020,3 genes,Wang-2020-Roles of the Hcp family proteins in,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17829,PHI:11152,UniProt,H9L4I8,GenBank,AKH05884,,,YU39,hcp2,,,,hcp1,UniProt: A0A0D6IDM0; GenBank: AKH08767,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,hemolysin-coregulated protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33300449,PubMed,10.1080/21505594.2020.1854538,Virulence. 2020 Dec;11(1):1716-1726,lilei@hsc.pku.edu.cn,All the mutants showed an internalization level similar to that of the wild type 14028s.,P Wang 2020,2020,3 genes,Wang-2020-Roles of the Hcp family proteins in,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17830,PHI:11153,,no data found,,,,,,hcp3,,,,hcp1,UniProt: A0A0D6IDM0; GenBank: AKH08767,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX4,,,,hemolysin-coregulated protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33300449,PubMed,10.1080/21505594.2020.1854538,Virulence. 2020 Dec;11(1):1716-1726,lilei@hsc.pku.edu.cn,All the mutants showed an internalization level similar to that of the wild type 14028s.,P Wang 2020,2020,3 genes,Wang-2020-Roles of the Hcp family proteins in,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17831,PHI:11151,UniProt,A0A0D6IDM0,GenBank,AKH08767,,,YU39,hcp1,,,,hcp2; hcp3,UniProt: H9L4I8; GenBank: AKH05884; UniProt: no data found; GenBank: no data found,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; colon,hemolysin-coregulated protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33300449,PubMed,10.1080/21505594.2020.1854538,Virulence. 2020 Dec;11(1):1716-1726,lilei@hsc.pku.edu.cn,All the mutants showed an internalization level similar to that of the wild type 14028s.,P Wang 2020,2020,3 genes,Wang-2020-Roles of the Hcp family proteins in,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17832,PHI:11152,UniProt,H9L4I8,GenBank,AKH05884,,,YU39,hcp2,,,,hcp1,UniProt: A0A0D6IDM0; GenBank: AKH08767,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; colon,hemolysin-coregulated protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33300449,PubMed,10.1080/21505594.2020.1854538,Virulence. 2020 Dec;11(1):1716-1726,lilei@hsc.pku.edu.cn,All the mutants showed an internalization level similar to that of the wild type 14028s.,P Wang 2020,2020,3 genes,Wang-2020-Roles of the Hcp family proteins in,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17833,PHI:11153,,no data found,,,,,,hcp3,,,,hcp1,UniProt: A0A0D6IDM0; GenBank: AKH08767,,28901,Salmonella enterica,588858,subsp. enterica serovar Typhimurium strain 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; colon,hemolysin-coregulated protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33300449,PubMed,10.1080/21505594.2020.1854538,Virulence. 2020 Dec;11(1):1716-1726,lilei@hsc.pku.edu.cn,All the mutants showed an internalization level similar to that of the wild type 14028s.,P Wang 2020,2020,3 genes,Wang-2020-Roles of the Hcp family proteins in,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17834,PHI:11154,UniProt,E9DY83,GenBank,EFY91418,,,CQMa 102,Macwh1 (MAC_02581),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,hemolymph,calcofluor white hypersensitive protein,,,,reduced virulence,,yes,yes,,,wild type,,wild type,wild type,no,CFW; Congo red; H2O2; SDS; sorbitol; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984; sorbitol: CHEBI:30911; NaCl: CHEBI:26710,,,,,gene disruption; gene complementation,,,YVS,33300230,PubMed,10.1002/ps.6218,Pest Manag Sci. 2021 Apr;77(4):1915-1924,yueqingcao@cqu.edu.cn,Both Macwh1 and Macwh43 affect the fungal cell wall ultrastructure and contribute to the stress tolerance and pest control potential in M. acrdium.,X Su 2020,2020,2 genes,Su-2020-Calcofluor white hypersensitive protei,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17835,PHI:11155,UniProt,E9EHY0,GenBank,EFY84471,,,CQMa 102,Macwh43 (MAC_09478),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,hemolymph,calcofluor white hypersensitive protein,,,,reduced virulence,,yes,yes,,,wild type,,wild type,wild type,no,CFW; Congo red; H2O2; SDS; sorbitol; NaCl,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984; sorbitol: CHEBI:30911; NaCl: CHEBI:26710,,,,,gene disruption; gene complementation,,,YVS,33300230,PubMed,10.1002/ps.6218,Pest Manag Sci. 2021 Apr;77(4):1915-1924,yueqingcao@cqu.edu.cn,Both Macwh1 and Macwh43 affect the fungal cell wall ultrastructure and contribute to the stress tolerance and pest control potential in M. acrdium.,X Su 2020,2020,2 genes,Su-2020-Calcofluor white hypersensitive protei,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17836,PHI:11156,UniProt,A0A1D8PG50,GenBank,AOW27114,,,SC5314,atp18 (CAALFM_C200610CA),chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; kidney,Su i/j subunit of F1FO-ATP synthase,,,,reduced virulence,,,,,,,,wild type,,no,fluconazole; amphotericin B; CFW; Congo red; H2O2; caspofungin; DPTA NONOate; LL-37,fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; caspofungin: CHEBI:474180; DPTA NONOate CAS: CAS:146724-95-0; LL-37: CHEBI:81664,,,,,gene deletion: full; gene complementation,,,YVS,33269392,PubMed,10.1093/mmy/myaa094,Med Mycol. 2020 Dec 2:myaa094,tzhangh@jnu.edu.cn,"Atp18 Δ/Δ mutant was more susceptible to attack by macrophages than wild type, which may correlate well with the abnormal cell wall function and increased sensitivity to oxidative stress. In contrast, no significant changes were observed for the atp19 Δ/Δ mutant.",Y Zhao 2020,2020,2 genes,Zhao-2020-The fungal-specific subunit i_j of F,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17837,PHI:11157,UniProt,A0A1D8PFD4,GenBank,AOW26850,,,SC5314,atp19 (CAALFM_C112320CA),chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; kidney,Su k subunit of F1FO-ATP synthase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,fluconazole; amphotericin B; CFW; Congo red; H2O2; caspofungin; DPTA NONOate; LL-37,fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; caspofungin: CHEBI:474180; DPTA NONOate CAS: CAS:146724-95-0; LL-37: CHEBI:81664,,,,,gene deletion: full; gene complementation,,,YVS,33269392,PubMed,10.1093/mmy/myaa094,Med Mycol. 2020 Dec 2:myaa094,tzhangh@jnu.edu.cn,"Atp18 Δ/Δ mutant was more susceptible to attack by macrophages than wild type, which may correlate well with the abnormal cell wall function and increased sensitivity to oxidative stress. In contrast, no significant changes were observed for the atp19 Δ/Δ mutant.",Y Zhao 2020,2020,2 genes,Zhao-2020-The fungal-specific subunit i_j of F,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17838,PHI:11156,UniProt,A0A1D8PG50,GenBank,AOW27114,,,SC5314,atp18 (CAALFM_C200610CA),chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,Su i/j subunit of F1FO-ATP synthase,,,,reduced virulence,,,,,,,,wild type,,no,fluconazole; amphotericin B; CFW; Congo red; H2O2; caspofungin; DPTA NONOate; LL-37,fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; caspofungin: CHEBI:474180; DPTA NONOate CAS: CAS:146724-95-0; LL-37: CHEBI:81664,,,,,gene deletion: full; gene complementation,,,YVS,33269392,PubMed,10.1093/mmy/myaa094,Med Mycol. 2020 Dec 2:myaa094,tzhangh@jnu.edu.cn,"Atp18 Δ/Δ mutant was more susceptible to attack by macrophages than wild type, which may correlate well with the abnormal cell wall function and increased sensitivity to oxidative stress. In contrast, no significant changes were observed for the atp19 Δ/Δ mutant.",Y Zhao 2020,2020,2 genes,Zhao-2020-The fungal-specific subunit i_j of F,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17839,PHI:11157,UniProt,A0A1D8PFD4,GenBank,AOW26850,,,SC5314,atp19 (CAALFM_C112320CA),chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,Su k subunit of F1FO-ATP synthase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,fluconazole; amphotericin B; CFW; Congo red; H2O2; caspofungin; DPTA NONOate; LL-37,fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; caspofungin: CHEBI:474180; DPTA NONOate CAS: CAS:146724-95-0; LL-37: CHEBI:81664,,,,,gene deletion: full; gene complementation,,,YVS,33269392,PubMed,10.1093/mmy/myaa094,Med Mycol. 2020 Dec 2:myaa094,tzhangh@jnu.edu.cn,"Atp18 Δ/Δ mutant was more susceptible to attack by macrophages than wild type, which may correlate well with the abnormal cell wall function and increased sensitivity to oxidative stress. In contrast, no significant changes were observed for the atp19 Δ/Δ mutant.",Y Zhao 2020,2020,2 genes,Zhao-2020-The fungal-specific subunit i_j of F,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17840,PHI:11158,UniProt,J9VLE6,GenBank,AFR92505,,,H99,ubi1 (CNAG_00370),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung,ubiquitin fusion protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,H2O2; NaNO2; NaCl; KCl; SDS; Congo red,"H2O2: CHEBI:16240; NaNO2: CHEBI:78870; NaCl: CHEBI:26710; KCl,  SDS: CHEBI:8984; Congo red: CHEBI:34653",,,,,gene deletion: full; gene complementation,,,YVS,33224112,PubMed,10.3389/fmicb.2020.570269,Front Microbiol. 2020 Nov 5;11:570269,weifang081782@163.com,"The ubi1Δ mutant displayed increased cell ploidy, cell cycle arrest, and decreased intracellular survival inside macrophages.",J Zhao 2020,2020,1 gene,Zhao-2020-Ribosomal Protein L40e Fused With a,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17841,PHI:11158,UniProt,J9VLE6,GenBank,AFR92505,,,H99,ubi1 (CNAG_00370),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,ubiquitin fusion protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,H2O2; NaNO2; NaCl; KCl; SDS; Congo red,"H2O2: CHEBI:16240; NaNO2: CHEBI:78870; NaCl: CHEBI:26710; KCl,  SDS: CHEBI:8984; Congo red: CHEBI:34653",,,,,gene deletion: full; gene complementation,,,YVS,33224112,PubMed,10.3389/fmicb.2020.570269,Front Microbiol. 2020 Nov 5;11:570269,weifang081782@163.com,"The ubi1Δ mutant displayed increased cell ploidy, cell cycle arrest, and decreased intracellular survival inside macrophages.",J Zhao 2020,2020,1 gene,Zhao-2020-Ribosomal Protein L40e Fused With a,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17842,PHI:11159,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,arv1,chromosome 3,,,erg11,UniProt: P10613; GenBank: CAA31658,,5476,Candida albicans,,W303a,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,reduced virulence,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence and cells expressing CaErg11 Y132F F145L did not reverse the lack of virulence using a disseminated candidiasis mouse model.,M Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17843,PHI:11159,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,arv1,chromosome 3,CaARV1 C3A; CaARV1 Y38A,,erg11,UniProt: P10613; GenBank: CAA31658,,5476,Candida albicans,,W303a,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,unaffected pathogenicity,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation; gene complementation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence and cells expressing CaErg11 Y132F F145L did not reverse the lack of virulence using a disseminated candidiasis mouse model.,M Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17844,PHI:11159,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,arv1,chromosome 3,CaARV1 C28A,,erg11,UniProt: P10613; GenBank: CAA31658,,5476,Candida albicans,,W303a,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,reduced virulence,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation; gene complementation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence and cells expressing CaErg11 Y132F F145L did not reverse the lack of virulence using a disseminated candidiasis mouse model.,M Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17845,PHI:11160,UniProt,P10613,GenBank,CAA31658,,,SC5314,erg11,,CaErg11 Y132L F145L,,arv1,UniProt: Q5ANH2; GenBank: AOW28488,,5476,Candida albicans,,W303a,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,lanosterol 14-alpha demethylase,,,,reduced virulence,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation; gene complementation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence and cells expressing CaErg11 Y132F F145L did not reverse the lack of virulence using a disseminated candidiasis mouse model.,M Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17846,PHI:11159,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,arv1,chromosome 3,CaARV1 C28A,,erg11,UniProt: P10613; GenBank: CAA31658,PHI:11160,5476,Candida albicans,,W303a,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,reduced virulence,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation; gene complementation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence and cells expressing CaErg11 Y132F F145L did not reverse the lack of virulence using a disseminated candidiasis mouse model.,M Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17847,PHI:11160,UniProt,P10613,GenBank,CAA31658,,,SC5314,erg11,,CaErg11 Y132L F145L,,arv1,UniProt: Q5ANH2; GenBank: AOW28488,PHI:11159,5476,Candida albicans,,W303a,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,lanosterol 14-alpha demethylase,,,,reduced virulence,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation; gene complementation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence and cells expressing CaErg11 Y132F F145L did not reverse the lack of virulence using a disseminated candidiasis mouse model.,M Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17848,PHI:11159,UniProt,Q5ANH2,GenBank,AOW28488,,,SC5314,arv1,chromosome 3,CaARV1 Y38A,,erg11,UniProt: P10613; GenBank: CAA31658,PHI:11160,5476,Candida albicans,,W303a,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,sterol homeostasis protein,,,,unaffected pathogenicity,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation; gene complementation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence and cells expressing CaErg11 Y132F F145L did not reverse the lack of virulence using a disseminated candidiasis mouse model.,M Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17849,PHI:11160,UniProt,P10613,GenBank,CAA31658,,,SC5314,erg11,,CaErg11 Y132L F145L,,arv1,UniProt: Q5ANH2; GenBank: AOW28488,PHI:11159,5476,Candida albicans,,W303a,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,lanosterol 14-alpha demethylase,,,,unaffected pathogenicity,,,,,,,,,,no,itraconazole; fluconazole,itraconazole: CHEBI:6076; fluconazole: CHEBI:46081,,,,,gene mutation; gene complementation,,,YVS,32678853,PubMed,10.1371/journal.pone.0235746,PLoS One. 2020 Jul 17;15(7):e0235746,jnickels@venenumbiodesign.com,Caarv1/Caarv1 cells expressing CaArv1 mutants unable to interact with CaErg11 were found to lack virulence and cells expressing CaErg11 Y132F F145L did not reverse the lack of virulence using a disseminated candidiasis mouse model.,M Villasmil 2020,2020,2 genes,Villasmil-2020-An Erg11 lanosterol 14-α-demeth,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17850,PHI:11161,UniProt,Q2YS30,GenBank,CAJ11366,,,2308,SerB (BAB1_1410),chromosome I,,,,,,29459,Brucella melitensis,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,"phosphoserine phosphatase SerB:haloacid dehalogenase-like hydrolase:HAD-superfamily hydrolase, subfamily IB",,,L-serine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31740531,PubMed,10.1128/IAI.00840-19,Infect Immun. 2020 Jan 22;88(2):e00840-19,dcomerci@iib.unsam.edu.ar,"The serB mutant was attenuated in the murine intraperitoneal infection model and had an altered lipid composition, since the lack of L-serine abrogated phosphatidylethanolamine synthesis in this strain.",V Revora 2019,2019,1 gene,Revora-2019-Brucella abortus depends on L-seri,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17851,PHI:11161,UniProt,Q2YS30,GenBank,CAJ11366,,,2308,SerB (BAB1_1410),chromosome I,,,,,,29459,Brucella melitensis,1310173,2308,brucellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,"phosphoserine phosphatase SerB:haloacid dehalogenase-like hydrolase:HAD-superfamily hydrolase, subfamily IB",,,L-serine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31740531,PubMed,10.1128/IAI.00840-19,Infect Immun. 2020 Jan 22;88(2):e00840-19,dcomerci@iib.unsam.edu.ar,"The serB mutant was attenuated in the murine intraperitoneal infection model and had an altered lipid composition, since the lack of L-serine abrogated phosphatidylethanolamine synthesis in this strain.",V Revora 2019,2019,1 gene,Revora-2019-Brucella abortus depends on L-seri,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17852,PHI:11161,UniProt,Q2YS30,GenBank,CAJ11366,,,2308,SerB (BAB1_1410),chromosome I,,,,,,29459,Brucella melitensis,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,"phosphoserine phosphatase SerB:haloacid dehalogenase-like hydrolase:HAD-superfamily hydrolase, subfamily IB",,,L-serine biosynthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31740531,PubMed,10.1128/IAI.00840-19,Infect Immun. 2020 Jan 22;88(2):e00840-19,dcomerci@iib.unsam.edu.ar,"The serB mutant was attenuated in the murine intraperitoneal infection model and had an altered lipid composition, since the lack of L-serine abrogated phosphatidylethanolamine synthesis in this strain.",V Revora 2019,2019,1 gene,Revora-2019-Brucella abortus depends on L-seri,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17853,PHI:11162,UniProt,Q2FH36,GenBank,ABD22065,,,USA300_FPR3757,msaB,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,cold shock protein,,,,reduced virulence,,,,,,,,,,no,H2O2; tert-butyl hydroperoxide; cumene hydroperoxide,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; cumene hydroperoxide: CHEBI:78673,,,,,gene deletion: full; gene complementation,,,YVS,31427392,PubMed,10.1128/JB.00417-19,J Bacteriol. 2019 Oct 4;201(21):e00417-19,mohamed.elasri@usm.edu,"The msaABCR mutant cells were significantly defective in intracellular survival within macrophages, human neutrophils, and whole-blood cells.",S Pandey 2019,2019,1 gene,Pandey-2019-The msaABCR operon regulates the r,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17854,PHI:11162,UniProt,Q2FH36,GenBank,ABD22065,,,USA300_FPR3757,msaB,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,neutrophil,cold shock protein,,,,reduced virulence,,,,,,,,,,no,H2O2; tert-butyl hydroperoxide; cumene hydroperoxide,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; cumene hydroperoxide: CHEBI:78673,,,,,gene deletion: full; gene complementation,,,YVS,31427392,PubMed,10.1128/JB.00417-19,J Bacteriol. 2019 Oct 4;201(21):e00417-19,mohamed.elasri@usm.edu,"The msaABCR mutant cells were significantly defective in intracellular survival within macrophages, human neutrophils, and whole-blood cells.",S Pandey 2019,2019,1 gene,Pandey-2019-The msaABCR operon regulates the r,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17855,PHI:11162,UniProt,Q2FH36,GenBank,ABD22065,,,USA300_FPR3757,msaB,,,,,,,1280,Staphylococcus aureus,,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,cold shock protein,,,,reduced virulence,,,,,,,,,,no,H2O2; tert-butyl hydroperoxide; cumene hydroperoxide,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; cumene hydroperoxide: CHEBI:78673,,,,,gene deletion: full; gene complementation,,,YVS,31427392,PubMed,10.1128/JB.00417-19,J Bacteriol. 2019 Oct 4;201(21):e00417-19,mohamed.elasri@usm.edu,"The msaABCR mutant cells were significantly defective in intracellular survival within macrophages, human neutrophils, and whole-blood cells.",S Pandey 2019,2019,1 gene,Pandey-2019-The msaABCR operon regulates the r,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17856,PHI:11162,UniProt,Q2FH36,GenBank,ABD22065,,,USA300_FPR3757,msaB,,,,,,,1280,Staphylococcus aureus,,UAMS-1,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,cold shock protein,,,,reduced virulence,,,,,,,,,,no,H2O2; tert-butyl hydroperoxide; cumene hydroperoxide,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; cumene hydroperoxide: CHEBI:78673,,,,,gene deletion: full; gene complementation,,,YVS,31427392,PubMed,10.1128/JB.00417-19,J Bacteriol. 2019 Oct 4;201(21):e00417-19,mohamed.elasri@usm.edu,"The msaABCR (msaB) mutant cells were significantly defective in intracellular survival within macrophages, human neutrophils, and whole-blood cells.",S Pandey 2019,2019,1 gene,Pandey-2019-The msaABCR operon regulates the r,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17857,PHI:11162,UniProt,Q2FH36,GenBank,ABD22065,,,USA300_FPR3757,msaB,,,,,,,1280,Staphylococcus aureus,,UAMS-1,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,neutrophil,cold shock protein,,,,reduced virulence,,,,,,,,,,no,H2O2; tert-butyl hydroperoxide; cumene hydroperoxide,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; cumene hydroperoxide: CHEBI:78673,,,,,gene deletion: full; gene complementation,,,YVS,31427392,PubMed,10.1128/JB.00417-19,J Bacteriol. 2019 Oct 4;201(21):e00417-19,mohamed.elasri@usm.edu,"The msaABCR mutant cells were significantly defective in intracellular survival within macrophages, human neutrophils, and whole-blood cells.",S Pandey 2019,2019,1 gene,Pandey-2019-The msaABCR operon regulates the r,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17858,PHI:11162,UniProt,Q2FH36,GenBank,ABD22065,,,USA300_FPR3757,msaB,,,,,,,1280,Staphylococcus aureus,,UAMS-1,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,cold shock protein,,,,reduced virulence,,,,,,,,,,no,H2O2; tert-butyl hydroperoxide; cumene hydroperoxide,H2O2: CHEBI:16240; tert-butyl hydroperoxide: CHEBI:64090; cumene hydroperoxide: CHEBI:78673,,,,,gene deletion: full; gene complementation,,,YVS,31427392,PubMed,10.1128/JB.00417-19,J Bacteriol. 2019 Oct 4;201(21):e00417-19,mohamed.elasri@usm.edu,"The msaABCR mutant cells were significantly defective in intracellular survival within macrophages, human neutrophils, and whole-blood cells.",S Pandey 2019,2019,1 gene,Pandey-2019-The msaABCR operon regulates the r,BATCH_104C,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17859,PHI:11163,UniProt,G8BET2,GenBank,CCE43721,,,CDC317,NDT80 (CPAR2-213640),,,,,,,5480,Candida parapsilosis,,BC014S,mycosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33538224,PubMed,10.1080/21505594.2021.1878743,Virulence. 2021 Dec;12(1):601-614,imiranda@med.up.pt,"Ndt80ΔΔ pseudohyphae adhered more rapidly and were more resistant to murine macrophage attack, becoming deleterious to such cells after phagocytosis.",J Branco 2021,2021,1 gene,Branco-2021-The transcription factor Ndt80 is,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17860,PHI:11164,UniProt,X0LE71,GenBank,EXM24118,,,25433,FoSOD5 (FOTG_08628),,,,,,,5507,Fusarium oxysporum,,FGSC 10442,vascular wilt (banana),eudicots,3635,Gossypium hirsutum (related: cotton),cv. FM1944,,,root,Sod_Cu domain-containing protein,,,,reduced virulence,,,,,,,,,,no,H2O2; diamide; SDS; NaNO2,H2O2: CHEBI:16240; diamide: CHEBI:48958; SDS: CHEBI:8984; NaNO2: CHEBI:78870,,,,,gene deletion: full; gene complementation,,,YVS,33737941,PubMed,10.3389/fpls.2021.608861,Front Plant Sci. 2021 Mar 2;12:608861,jjc0032@auburn.edu,An extracellular SOD (FoSod5) from Fov was important for tolerance to multiple ROS and was required for full virulence on cotton.,Q Wang 2021,2021,1 gene,Wang-2021-The Extracellular Superoxide Dismuta,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17861,PHI:11165,UniProt,A0A161PSJ4,GenBank,AQY22467,,,HXb2,Fur,,,,,,,34085,Riemerella anatipestifer,1228997,RA-CH-1,septicemia anserum exsudativa,birds,8839,Anas platyrhynchos (related: mallard),,,,spleen; heart; liver; brain,ferric uptake regulation protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33741064,PubMed,10.1186/s13567-021-00919-9,Vet Res. 2021 Mar 19;52(1):48,chenganchun@vip.163.com,The fur mutation led to reduced virulence of R. anatipestifer CH-1 in ducklings.,M Huang 2021,2021,1 gene,Huang-2021-Functional characterization of Fur,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17862,PHI:11166,UniProt,A0A0H2UT66,GenBank,AAM78739,,,MGAS315,spoV (spyM3_0132),,,,,,,1314,Streptococcus pyogenes,,MGAS315,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,streptococcal peptide controlling virulence,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33722844,PubMed,10.1128/JB.00586-20,J Bacteriol. 2021 Mar 15:JB.00586-20,michael.chaussee@usd.edu,The deletion of spoV decreased GAS survival in murine blood.,A L Herrera 2021,2021,1 gene,Herrera-2021-The Streptococcus pyogenes signal,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17863,PHI:11167,,no data found,,,,,,Pdr802,,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; blood; brain,transcription factor,,,,reduced virulence,,,,,,,,,,no,sorbitol; NaCl; CaCl2; LiCl; Congo red; calcofluor white; caffeine; SDS; NaNO2; H2O2; ethanol,sorbitol: CHEBI:30911; NaCl: CHEBI:26710; CaCl2: CHEBI:3312; LiCl: CHEBI:48607; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; caffeine: CHEBI:27732; SDS: CHEBI:8984; NaNO2: CHEBI:78870; H2O2: CHEBI:16240; ethanol: CHEBI:16236,,,,,gene deletion: full; gene complementation,,,YVS,33688010,PubMed,10.1128/mBio.03457-20,mBio. 2021 Mar 9;12(2):e03457-20,doering@wustl.edu,"Cryptococci engineered to lack Pdr802 showed a dramatic increase in Titan cells, which are not phagocytosed and have diminished ability to directly cross biological barriers.",J C Reuwsaat 2021,2021,1 gene,Reuwsaat-2021-The Transcription Factor Pdr802,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17864,PHI:11168,UniProt,J0JQ36,GenBank,EJB40285,,,NQ4161,dppA,,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,dipeptide transporter-substrate binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33732225,PubMed,10.3389/fmicb.2021.633166,Front Microbiol. 2021 Feb 25;12:633166,shefeifei@yeah.net,"Although Dpp transporter-deficient strains proliferated slower, they were associated with higher bacterial adhesion and T4SS expression and induced a stronger inflammatory response in AGS cells.",X Xu 2021,2021,1 gene,Xu-2021-The Role of a Dipeptide Transporter in,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17865,PHI:11168,UniProt,J0JQ36,GenBank,EJB40285,,,NQ4161,dppA,,,,,,,210,Helicobacter pylori,102618,ATCC 43504,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,dipeptide transporter-substrate binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33732225,PubMed,10.3389/fmicb.2021.633166,Front Microbiol. 2021 Feb 25;12:633166,shefeifei@yeah.net,"Although Dpp transporter-deficient strains proliferated slower, they were associated with higher bacterial adhesion and T4SS expression and induced a stronger inflammatory response in AGS cells.",X Xu 2021,2021,1 gene,Xu-2021-The Role of a Dipeptide Transporter in,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17866,PHI:11169,UniProt,P37669,GenBank,AAB18538,,,K-12,ataT,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colorectal adenocarcinoma cell line,Gcn5-related N-acetyltransferase (GNAT) family toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33732222,PubMed,10.3389/fmicb.2021.627141,Front Microbiol. 2021 Mar 1;12:627141,wanghui_dyx@hotmail.com,"In the absence of ataT, strains showed a lower adhesion number, and host cells presented weaker attaching and effacing lesions, inflammatory response, and pathological injury.",Z He 2021,2021,3 genes,He-2021-AtaT Improves the Stability of Pore-Fo,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17867,PHI:11169,UniProt,P37669,GenBank,AAB18538,,,K-12,ataT,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,Gcn5-related N-acetyltransferase (GNAT) family toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33732222,PubMed,10.3389/fmicb.2021.627141,Front Microbiol. 2021 Mar 1;12:627141,wanghui_dyx@hotmail.com,"In the absence of ataT, strains showed a lower adhesion number, and host cells presented weaker attaching and effacing lesions, inflammatory response, and pathological injury.",Z He 2021,2021,3 genes,He-2021-AtaT Improves the Stability of Pore-Fo,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17868,PHI:11170,,no data found,,,,,,ataR,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,antitoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33732222,PubMed,10.3389/fmicb.2021.627141,Front Microbiol. 2021 Mar 1;12:627141,wanghui_dyx@hotmail.com,"In the absence of ataT, strains showed a lower adhesion number, and host cells presented weaker attaching and effacing lesions, inflammatory response, and pathological injury.",Z He 2021,2021,3 genes,He-2021-AtaT Improves the Stability of Pore-Fo,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17869,PHI:11171,UniProt,Q05129,GenBank,CAA79733,,,E2348/69,espB,,K206Q,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,secreted protein B,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33732222,PubMed,10.3389/fmicb.2021.627141,Front Microbiol. 2021 Mar 1;12:627141,wanghui_dyx@hotmail.com,"In the absence of ataT, strains showed a lower adhesion number, and host cells presented weaker attaching and effacing lesions, inflammatory response, and pathological injury.",Z He 2021,2021,3 genes,He-2021-AtaT Improves the Stability of Pore-Fo,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17870,PHI:11171,UniProt,Q05129,GenBank,CAA79733,,,E2348/69,espB,,K206R; K206A,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,secreted protein B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33732222,PubMed,10.3389/fmicb.2021.627141,Front Microbiol. 2021 Mar 1;12:627141,wanghui_dyx@hotmail.com,"In the absence of ataT, strains showed a lower adhesion number, and host cells presented weaker attaching and effacing lesions, inflammatory response, and pathological injury.",Z He 2021,2021,3 genes,He-2021-AtaT Improves the Stability of Pore-Fo,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17871,PHI:11172,UniProt,J4UN91,GenBank,EJP66492,,,ARSEF 2860,ubr1 (BBA_04432),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,E3 ubiquitin-protein ligase,,,,reduced virulence,,,,,,reduced,,reduced,,no,CFW; Congo red; H2O2; menadione; NaCl; sorbitol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,33686455,PubMed,10.1007/s00253-021-11222-0,Appl Microbiol Biotechnol. 2021 Apr;105(7):2747-2758,mgfeng@zju.edu.cn,"The disruptant was compromised in polar growth featured with curved or hook-like germ tubes and abnormally branched hyphae, leading to impeded propagation of aberrant hyphal bodies in infected insect hemocoel and attenuated virulence.",D Y Wang 2021,2021,1 gene,Wang-2021-Ubr1-mediated ubiquitylation orchest,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17872,PHI:11173,,no data found,,,,,,esrF,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33688013,PubMed,10.1128/mBio.03605-20,mBio. 2021 Mar 9;12(2):e03605-20,liubin1981@nankai.edu.cn,An infant rabbit model of O157 infection showed that deletion of esrF and flhB significantly attenuated O157 pathogenicity.,T Jia 2021,2021,2 genes,Jia-2021-A Novel Small RNA Promotes Motility a,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17873,PHI:11173,,no data found,,,,,,esrF,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,colon,small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33688013,PubMed,10.1128/mBio.03605-20,mBio. 2021 Mar 9;12(2):e03605-20,liubin1981@nankai.edu.cn,An infant rabbit model of O157 infection showed that deletion of esrF and flhB significantly attenuated O157 pathogenicity.,T Jia 2021,2021,2 genes,Jia-2021-A Novel Small RNA Promotes Motility a,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17874,PHI:11174,UniProt,P76299,GenBank,AAC74950,,,K-12,flhB,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,flagellar biosynthetic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33688013,PubMed,10.1128/mBio.03605-20,mBio. 2021 Mar 9;12(2):e03605-20,liubin1981@nankai.edu.cn,An infant rabbit model of O157 infection showed that deletion of esrF and flhB significantly attenuated O157 pathogenicity.,T Jia 2021,2021,2 genes,Jia-2021-A Novel Small RNA Promotes Motility a,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17875,PHI:11174,UniProt,P76299,GenBank,AAC74950,,,K-12,flhB,,,,,,,562,Escherichia coli,155864,serotype O157:H7 strain EDL933,neonatal sepsis; neonatal meningitis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,colon,flagellar biosynthetic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33688013,PubMed,10.1128/mBio.03605-20,mBio. 2021 Mar 9;12(2):e03605-20,liubin1981@nankai.edu.cn,An infant rabbit model of O157 infection showed that deletion of esrF and flhB significantly attenuated O157 pathogenicity.,T Jia 2021,2021,2 genes,Jia-2021-A Novel Small RNA Promotes Motility a,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17876,PHI:11175,UniProt,A0A0H3NII0,GenBank,CBW16590,,,SL1344,SL1344_0490 (ScwA),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SV5015,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,probable secreted protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33679664,PubMed,10.3389/fmicb.2021.633701,Front Microbiol. 2021 Feb 19;12:633701,fgportillo@cnb.csic.es,ScwA deficiency resulted in a hypervirulent phenotype in the murine typhoid model.,J J Cestero 2021,2021,1 gene,Cestero-2021-A Novel Salmonella Periplasmic Pr,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17877,PHI:11175,UniProt,A0A0H3NII0,GenBank,CBW16590,,,SL1344,SL1344_0490 (ScwA),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SV5015,salmonellosis,rodents,10116,Rattus norvegicus (related: norway rat),NRK-49F cell line,,,fibroblast,probable secreted protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33679664,PubMed,10.3389/fmicb.2021.633701,Front Microbiol. 2021 Feb 19;12:633701,fgportillo@cnb.csic.es,ScwA deficiency resulted in a hypervirulent phenotype in the murine typhoid model.,J J Cestero 2021,2021,1 gene,Cestero-2021-A Novel Salmonella Periplasmic Pr,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17878,PHI:11175,UniProt,A0A0H3NII0,GenBank,CBW16590,,,SL1344,SL1344_0490 (ScwA),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SV5015,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,probable secreted protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33679664,PubMed,10.3389/fmicb.2021.633701,Front Microbiol. 2021 Feb 19;12:633701,fgportillo@cnb.csic.es,ScwA deficiency resulted in a hypervirulent phenotype in the murine typhoid model.,J J Cestero 2021,2021,1 gene,Cestero-2021-A Novel Salmonella Periplasmic Pr,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17879,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. vasinfectum,vascular wilt (banana),eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf; seedling,secreted glycoside hydrolase family 12 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17880,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. vasinfectum,vascular wilt (banana),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf; seedling,secreted glycoside hydrolase family 12 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17881,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. vasinfectum,vascular wilt (banana),eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,secreted glycoside hydrolase family 12 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17882,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. vasinfectum,vascular wilt (banana),eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,leaf,secreted glycoside hydrolase family 12 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17883,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. vasinfectum,vascular wilt (banana),eudicots,3847,Glycine max (related: soybean),,,,leaf,secreted glycoside hydrolase family 12 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17884,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. vasinfectum,vascular wilt (banana),eudicots,4577,Zea mays (related: maize),,,,leaf,secreted glycoside hydrolase family 12 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17885,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. vasinfectum,vascular wilt (banana),eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted glycoside hydrolase family 12 protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17886,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,vascular wilt (banana),eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf; seedling,secreted glycoside hydrolase family 12 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17887,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,vascular wilt (banana),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf; seedling,secreted glycoside hydrolase family 12 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17888,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,vascular wilt (banana),eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,secreted glycoside hydrolase family 12 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17889,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,vascular wilt (banana),eudicots,4097,Nicotiana tabacum (related: common tobacco) (non-host bioassay),,,,leaf,secreted glycoside hydrolase family 12 protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17890,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,vascular wilt (banana),eudicots,3847,Glycine max (related: soybean),,,,leaf,secreted glycoside hydrolase family 12 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17891,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,vascular wilt (banana),eudicots,4577,Zea mays (related: maize),,,,leaf,secreted glycoside hydrolase family 12 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17892,PHI:11176,UniProt,X0MKY5,GenBank,EXM34257,,,25433,FoEG1 (FOTG_02663),,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,vascular wilt (banana),eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,secreted glycoside hydrolase family 12 protein,,,,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33675158,PubMed,10.1111/mpp.13041,Mol Plant Pathol. 2021 Mar 5,zenghongmei@caas.cn,FoEG1 deletion or loss of enzyme activity reduced the virulence of F. oxysporum.,L Zhang 2021,2021,1 gene,"Zhang-2021-FoEG1, a secreted glycoside hydrola",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17893,PHI:11177,,no data found,GenBank,AFM51648,,,HB0801,Mbov_0280,,,,,,,28903,Mycoplasmopsis bovis,,HB0801,,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: recombinant protein,,,YVS,33659004,PubMed,10.3389/fimmu.2021.619362,Front Immunol. 2021 Feb 15;12:619362,aizhen@mail.hzau.edu.cn,"MbovP280, a novel secreted protein of M. bovis induced the apoptosis of BoMac via its coiled-coil domain and cellular ligand CRYAB.",G Zhao 2021,2021,2 genes,Zhao-2021-Novel Secreted Protein of Mycoplasma,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17894,PHI:11177,,no data found,GenBank,AFM51648,,,HB0801,Mbov_0280,,,,,,,28903,Mycoplasmopsis bovis,,HB0801,,even-toed ungulates,9913,Bos taurus (related: cattle),BoMac cell line,,,macrophage,putative lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: recombinant protein,,,YVS,33659004,PubMed,10.3389/fimmu.2021.619362,Front Immunol. 2021 Feb 15;12:619362,aizhen@mail.hzau.edu.cn,"MbovP280, a novel secreted protein of M. bovis induced the apoptosis of BoMac via its coiled-coil domain and cellular ligand CRYAB.",G Zhao 2021,2021,2 genes,Zhao-2021-Novel Secreted Protein of Mycoplasma,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17895,PHI:11178,,no data found,GenBank,AFM51831,,,HB0801,Mbov_0475,,,,,,,28903,Mycoplasmopsis bovis,,HB0801,,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: recombinant protein,,,YVS,33659004,PubMed,10.3389/fimmu.2021.619362,Front Immunol. 2021 Feb 15;12:619362,aizhen@mail.hzau.edu.cn,"MbovP280, a novel secreted protein of M. bovis induced the apoptosis of BoMac via its coiled-coil domain and cellular ligand CRYAB.",G Zhao 2021,2021,2 genes,Zhao-2021-Novel Secreted Protein of Mycoplasma,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17896,PHI:11178,,no data found,GenBank,AFM51831,,,HB0801,Mbov_0475,,,,,,,28903,Mycoplasmopsis bovis,,HB0801,,even-toed ungulates,9913,Bos taurus (related: cattle),BoMac cell line,,,macrophage,putative lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: recombinant protein,,,YVS,33659004,PubMed,10.3389/fimmu.2021.619362,Front Immunol. 2021 Feb 15;12:619362,aizhen@mail.hzau.edu.cn,"MbovP280, a novel secreted protein of M. bovis induced the apoptosis of BoMac via its coiled-coil domain and cellular ligand CRYAB.",G Zhao 2021,2021,2 genes,Zhao-2021-Novel Secreted Protein of Mycoplasma,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17897,PHI:11179,UniProt,A0A0K0GND9,GenBank,ACD60357,,,PXO99A,gdpX6 (PXO_02019),,GdpX6 D403A,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,diguanylate cyclase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33652966,PubMed,10.3390/microorganisms9030495,Microorganisms. 2021 Feb 26;9(3):495,yangfenghuan@caas.cn,"Deletion of gdpX6 significantly increased the virulence, swimming motility, and decreased sliding motility and biofilm formation.",W Yan 2021,2021,1 gene,Yan-2021-Diguanylate Cyclase GdpX6 with c-di-G,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17898,PHI:11179,UniProt,A0A0K0GND9,GenBank,ACD60357,,,PXO99A,gdpX6 (PXO_02019),,GdpX6 D403A,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33652966,PubMed,10.3390/microorganisms9030495,Microorganisms. 2021 Feb 26;9(3):495,yangfenghuan@caas.cn,"Deletion of gdpX6 significantly increased the virulence, swimming motility, and decreased sliding motility and biofilm formation.",W Yan 2021,2021,1 gene,Yan-2021-Diguanylate Cyclase GdpX6 with c-di-G,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17899,PHI:11179,UniProt,A0A0K0GND9,GenBank,ACD60357,,,PXO99A,gdpX6 (PXO_02019),,GdpX6 E411A,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33652966,PubMed,10.3390/microorganisms9030495,Microorganisms. 2021 Feb 26;9(3):495,yangfenghuan@caas.cn,"Deletion of gdpX6 significantly increased the virulence, swimming motility, and decreased sliding motility and biofilm formation.",W Yan 2021,2021,1 gene,Yan-2021-Diguanylate Cyclase GdpX6 with c-di-G,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17900,PHI:11179,UniProt,A0A0K0GND9,GenBank,ACD60357,,,PXO99A,gdpX6 (PXO_02019),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33652966,PubMed,10.3390/microorganisms9030495,Microorganisms. 2021 Feb 26;9(3):495,yangfenghuan@caas.cn,"Deletion of gdpX6 significantly increased the virulence, swimming motility, and decreased sliding motility and biofilm formation.",W Yan 2021,2021,1 gene,Yan-2021-Diguanylate Cyclase GdpX6 with c-di-G,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17901,PHI:11179,UniProt,A0A0K0GND9,GenBank,ACD60357,,,PXO99A,gdpX6 (PXO_02019),,GdpX6 E411A,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,diguanylate cyclase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33652966,PubMed,10.3390/microorganisms9030495,Microorganisms. 2021 Feb 26;9(3):495,yangfenghuan@caas.cn,"Deletion of gdpX6 significantly increased the virulence, swimming motility, and decreased sliding motility and biofilm formation.",W Yan 2021,2021,1 gene,Yan-2021-Diguanylate Cyclase GdpX6 with c-di-G,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17902,PHI:11180,UniProt,Q5AGY8,GenBank,AOW30541,,,SC5314,Mcp1 (orf 19.6550),chromosome 7,,,,,,5476,Candida albicans,,BWP17,oral candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,core component of vacuole and mitochondria patch (vCLAMP) protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33633712,PubMed,10.3389/fmicb.2021.633380,Front Microbiol. 2021 Feb 4;12:633380,nklimingchun@163.com,Deletion of MCP1 inhibited filamentous growth and impaired virulence of the pathogen.,X Mao 2021,2021,1 gene,Mao-2021-The Vacuole and Mitochondria Patch (v,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17903,PHI:11181,UniProt,A0A1D8PGN0,GenBank,AOW27284,,,SC5314,Vam6 (orf 19.1567),chromosome 2,,,,,,5476,Candida albicans,,BWP17,oral candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,vacuole and mitochondria patch (vCLAMP) protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33478009,PubMed,10.3390/antiox10010136,Antioxidants (Basel). 2021 Jan 19;10(1):136,nklimingchun@163.com,"The results showed that the vam6Δ/Δ mutant exhibited obvious mitochondrial swelling, mtDNA damage, reduced activity of antioxidant enzymes, and abnormal vacuolar morphology under H2O2 treatment.",X Mao 2021,2021,1 gene,Mao-2021-Vacuole and Mitochondria Patch (vCLAM,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17904,PHI:11181,UniProt,A0A1D8PGN0,GenBank,AOW27284,,,SC5314,Vam6 (orf 19.1567),chromosome 2,,,,,,5476,Candida albicans,,BWP17,oral candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,vacuole and mitochondria patch (vCLAMP) protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33478009,PubMed,10.3390/antiox10010136,Antioxidants (Basel). 2021 Jan 19;10(1):136,nklimingchun@163.com,"The results showed that the vam6Δ/Δ mutant exhibited obvious mitochondrial swelling, mtDNA damage, reduced activity of antioxidant enzymes, and abnormal vacuolar morphology under H2O2 treatment.",X Mao 2021,2021,1 gene,Mao-2021-Vacuole and Mitochondria Patch (vCLAM,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17905,PHI:11182,UniProt,Q9I589,GenBank,AE004520_4,,,PAO1,CbpD,,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; liver; kidney; spleen,lytic polysaccharide monooxygenase; chitin-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33623002,PubMed,10.1038/s41467-021-21473-0,Nat Commun. 2021 Feb 23;12(1):1230,gustav.vaaje-kolstad@nmbu.no,"Deletion of cbpD rendered P. aeruginosa unable to establish a lethal systemic infection, associated with enhanced bacterial clearance in vivo.",F Askarian 2021,2021,1 gene,Askarian-2021-The lytic polysaccharide monooxy,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17906,PHI:11183,UniProt,Q6FKK2,GenBank,CAG62216,,,CBS 138,CgTPO4 (CAGL0L10912g),chromosome L,,,,,,5478,Candida glabrata,,KUE100,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,polyamine transporter 4,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33573089,PubMed,10.3390/ijms22031376,Int J Mol Sci. 2021 Jan 29;22(3):1376,mnpct@tecnico.ulisboa.pt,CgTPO4 gene was found to be required for the C.glabrata ability to kill G.mellonella.,M Cavalheiro 2021,2021,1 gene,Cavalheiro-2021-Role of CgTpo4 in Polyamine an,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17907,PHI:11184,UniProt,A0A384JHK6,GenBank,ATZ49911,,,B05.10,BcCyp2 (BCIN_05g03080),BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,peptidyl-prolyl cis-trans isomerase,,,,reduced virulence,,,,,,reduced; aberrant,,wild type,reduced,no,H2O2; NaCl; KCl; SDS; Congo red; cyclosporine A,H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; SDS: CHEBI:8984; Congo red: CHEBI:34653; cyclosporine A: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,33567582,PubMed,10.3390/ijms22041694,Int J Mol Sci. 2021 Feb 8;22(4):1694,liguihua@jlu.edu.cn,"Disruption of cyclophilin gene BcCYP2 did not impair the pathogen mycelial growth, osmotic and oxidative stress adaptation as well as cell wall integrity, but delayed conidial germination and germling development, altered conidial and sclerotial morphology, reduced infection cushion (IC) formation, sclerotial production and virulence.",J Sun 2021,2021,1 gene,Sun-2021-Cyclophilin BcCyp2 Regulates Infection-Related,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17908,PHI:11184,UniProt,A0A384JHK6,GenBank,ATZ49911,,,B05.10,BcCyp2 (BCIN_05g03080),BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Smoothie,,,fruit,peptidyl-prolyl cis-trans isomerase,,,,reduced virulence,,,,,,reduced; aberrant,,wild type,reduced,no,H2O2; NaCl; KCl; SDS; Congo red; cyclosporine A,H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; SDS: CHEBI:8984; Congo red: CHEBI:34653; cyclosporine A: CHEBI:4031,,,,,gene deletion: full; gene complementation,,,YVS,33567582,PubMed,10.3390/ijms22041694,Int J Mol Sci. 2021 Feb 8;22(4):1694,liguihua@jlu.edu.cn,"Disruption of cyclophilin gene BcCYP2 did not impair the pathogen mycelial growth, osmotic and oxidative stress adaptation as well as cell wall integrity, but delayed conidial germination and germling development, altered conidial and sclerotial morphology, reduced infection cushion (IC) formation, sclerotial production and virulence.",J Sun 2021,2021,1 gene,Sun-2021-Cyclophilin BcCyp2 Regulates Infection-Related,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17909,PHI:11185,,no data found,,,,,,FgGyp1 (FGSG_17336),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,GTPase-activating protein,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33552040,PubMed,10.3389/fmicb.2021.621519,Front Microbiol. 2021 Jan 21;12:621519,zhw@mju.edu.cn,"FgGyp1 was important for vegetative growth, conidiation and virulence, and negatively regulated DON biosynthesis in F. graminearum.",Q Zheng 2021,2021,1 gene,Zheng-2021-The GTPase-Activating Protein FgGyp,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17910,PHI:11186,,no data found,,,,,,kpfR,,,,,,,573,Klebsiella pneumoniae,,UKP8,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bladder,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33552015,PubMed,10.3389/fmicb.2020.601921,Front Microbiol. 2021 Jan 21;11:601921,lucio.ferraz@usf.edu.br,K. pneumoniae with disrupted kpfR gene exhibited a hyperfimbriated phenotype with enhanced biofilm formation and greater adhesion to and replication within epithelial host cells.,A E I Gomes 2020,2020,1 gene,"Gomes AÉ-2020-Functional Insights From KpfR, a",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17911,PHI:11186,,no data found,,,,,,kpfR,,,,,,,573,Klebsiella pneumoniae,,UKP8,pneumonia,primates,9606,Homo sapiens (related: human),T24 cell line,,,T-24 cell,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33552015,PubMed,10.3389/fmicb.2020.601921,Front Microbiol. 2021 Jan 21;11:601921,lucio.ferraz@usf.edu.br,K. pneumoniae with disrupted kpfR gene exhibited a hyperfimbriated phenotype with enhanced biofilm formation and greater adhesion to and replication within epithelial host cells.,A E I Gomes 2020,2020,1 gene,"Gomes AÉ-2020-Functional Insights From KpfR, a",BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17912,PHI:11187,UniProt,A0A0H3B2K4,GenBank,ACA68070,,,YPIII,MAM (YPK_1779),,,,,,,633,Yersinia pseudotuberculosis,,YP126,zoonotic infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemocyte,mammalian cell entry related domain protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33550901,PubMed,10.1080/21505594.2021.1878672,Virulence. 2021 Dec;12(1):638-653,jenson.lim@stir.ac.uk,"Loss of MAM, and deficient microbe–phagocyte interaction, increased pathogenesis in G. mellonella.",A M Krachler 2021,2021,1 gene,Krachler-2021-Defective phagocyte association,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17913,PHI:11188,UniProt,O53777,GenBank,CCP43318,,,H37Rv,Rv0580c,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,H2O2; SDS; amikacin; vancomycin; erythromycin; roxithromycin,H2O2: CHEBI:16240; SDS: CHEBI:8984; amikacin: CHEBI:2637; vancomycin: CHEBI:28001; erythromycin: CHEBI:48923; roxithromycin: CHEBI:48844,,,,,heterologous expression,,,YVS,33535567,PubMed,10.3390/pathogens10020143,Pathogens. 2021 Feb 1;10(2):143,georgex@swu.edu.cn,Rv0580c reduced the intracellular survival of bacilli.,M K Ali 2021,2021,1 gene,Ali-2021-Mycobacterium tuberculosis Rv0580c Im,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17914,PHI:11189,UniProt,B8F6H2,GenBank,ACL32924,,,SH0165,potD,,,,,,,738,Glaesserella parasuis,,SC1401,Glasser's disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,polyamine transport protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; SDS,H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,33525975,PubMed,10.1080/21505594.2021.1878673,Virulence. 2021 Dec;12(1):520-546,wyp@sicau.edu.cn,"PotD from G. parasuis had a high binding potential to polyamine, and was essential for the full bacterial virulence within mouse models.",K Dai 2021,2021,1 gene,Dai-2021-Deletion of Polyamine Transport Prote,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17915,PHI:11189,UniProt,B8F6H2,GenBank,ACL32924,,,SH0165,potD,,,,,,,738,Glaesserella parasuis,,SC1401,Glasser's disease,even-toed ungulates,9823,Sus scrofa (related: Pig),PK-15 cell line,,,PK-15 cell,polyamine transport protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; SDS,H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,33525975,PubMed,10.1080/21505594.2021.1878673,Virulence. 2021 Dec;12(1):520-546,wyp@sicau.edu.cn,Planktonic ΔpotD::Kan demonstrated decreased adherence and invasion abilities.,K Dai 2021,2021,1 gene,Dai-2021-Deletion of Polyamine Transport Prote,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17916,PHI:11189,UniProt,B8F6H2,GenBank,ACL32924,,,SH0165,potD,,,,,,,738,Glaesserella parasuis,,SC1401,Glasser's disease,rodents,10090,Mus musculus (related: house mouse),MLE-12 cell line,,,lung epithelial cell,polyamine transport protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; SDS,H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,33525975,PubMed,10.1080/21505594.2021.1878673,Virulence. 2021 Dec;12(1):520-546,wyp@sicau.edu.cn,Planktonic ΔpotD::Kan demonstrated decreased adherence and invasion abilities.,K Dai 2021,2021,1 gene,Dai-2021-Deletion of Polyamine Transport Prote,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17917,PHI:11190,,no data found,,,,,,CgPTPM1,,,,,,,31870,Colletotrichum graminicola,645133,M1.001,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Xianyu 335,,,leaf,mitochondrial protein tyrosine phosphatase,,,,reduced virulence,,yes,yes,,,reduced,,wild type,reduced,no,H2O2; NaCl; sorbitol; Congo red; SDS,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,33519752,PubMed,10.3389/fmicb.2020.605738,Front Microbiol. 2021 Jan 14;11:605738,zhangsh89@syau.edu.cn,"The ΔCgPTPM1 mutant strains exhibited an obvious reduction of virulence, and the delayed infected hyphae failed to expand in the host cells.",S Wang 2020,2020,1 gene,Wang-2020-Involvement of the Mitochondrial Pro,BATCH_105A,2021-03-01,MC,,,,,,,,,,,,,
,,Record 17918,PHI:11191,,no data found,GenBank,6EZV_X,,,,makA,,,,,,,666,Vibrio cholerae,,serotype O1 biovar El Tor strain A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,cytotoxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33735319,PubMed,10.1371/journal.ppat.1009414,PLoS Pathog. 2021 Mar 18;17(3):e1009414,sun.nyunt.wai@umu.se,"Data from bacterial colonization in a mouse infection model suggested that MakA might acted as an anti-colonization factor of V. cholerae, presumably expressed during later stage(s) of infection.",A Nadeem 2021,2021,1 gene,Nadeem-2021-Phosphatidic acid-mediated binding,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17919,PHI:11192,UniProt,I4E2I1,GenBank,CCA41203,,,,VEL1 (VDAG_JR2_Chr7g04890a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling; root,velvet-like protein 1,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33720931,PubMed,10.1371/journal.pgen.1009434,PLoS Genet. 2021 Mar 15;17(3):e1009434,gbraus@gwdg.de,Vel1 was necessary for initial plant root colonization and together with Vel3 for propagation in planta by conidiation.,A M Hofer 2021,2021,4 genes,Höfer-2021-The velvet protein Vel1 controls in,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17920,PHI:11193,,no data found,,,,,,VEL3 (VDAG_JR2_Chr6g00630a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling; root,velvet protein,,,,increased virulence (hypervirulence),,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33720931,PubMed,10.1371/journal.pgen.1009434,PLoS Genet. 2021 Mar 15;17(3):e1009434,gbraus@gwdg.de,Vel1 was necessary for initial plant root colonization and together with Vel3 for propagation in planta by conidiation.,A M Hofer 2021,2021,4 genes,Höfer-2021-The velvet protein Vel1 controls in,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17921,PHI:11192,UniProt,I4E2I1,GenBank,CCA41203,,,,VEL1 (VDAG_JR2_Chr7g04890a),,,,,,PHI:11193,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling; root,velvet-like protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33720931,PubMed,10.1371/journal.pgen.1009434,PLoS Genet. 2021 Mar 15;17(3):e1009434,gbraus@gwdg.de,Vel1 was necessary for initial plant root colonization and together with Vel3 for propagation in planta by conidiation.,A M Hofer 2021,2021,4 genes,Höfer-2021-The velvet protein Vel1 controls in,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17922,PHI:11193,,no data found,,,,,,VEL3 (VDAG_JR2_Chr6g00630a),,,,,,PHI:11192,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling; root,velvet protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33720931,PubMed,10.1371/journal.pgen.1009434,PLoS Genet. 2021 Mar 15;17(3):e1009434,gbraus@gwdg.de,Vel1 was necessary for initial plant root colonization and together with Vel3 for propagation in planta by conidiation.,A M Hofer 2021,2021,4 genes,Höfer-2021-The velvet protein Vel1 controls in,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17923,PHI:11194,,no data found,,,,,,VOS1 (VDAG_JR2_Chr3g12090a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling; root,velvet protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33720931,PubMed,10.1371/journal.pgen.1009434,PLoS Genet. 2021 Mar 15;17(3):e1009434,gbraus@gwdg.de,Vel1 was necessary for initial plant root colonization and together with Vel3 for propagation in planta by conidiation.,A M Hofer 2021,2021,4 genes,Höfer-2021-The velvet protein Vel1 controls in,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17924,PHI:11195,,no data found,,,,,,VEL2 (VDAG_JR2_Chr3g06150a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling; root,velvet protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33720931,PubMed,10.1371/journal.pgen.1009434,PLoS Genet. 2021 Mar 15;17(3):e1009434,gbraus@gwdg.de,Vel1 was necessary for initial plant root colonization and together with Vel3 for propagation in planta by conidiation.,A M Hofer 2021,2021,4 genes,Höfer-2021-The velvet protein Vel1 controls in,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17925,PHI:11192,UniProt,I4E2I1,GenBank,CCA41203,,,,VEL1 (VDAG_JR2_Chr7g04890a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,root,velvet-like protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33720931,PubMed,10.1371/journal.pgen.1009434,PLoS Genet. 2021 Mar 15;17(3):e1009434,gbraus@gwdg.de,Vel1 was necessary for initial plant root colonization and together with Vel3 for propagation in planta by conidiation.,A M Hofer 2021,2021,4 genes,Höfer-2021-The velvet protein Vel1 controls in,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17926,PHI:11196,,no data found,,,,,,CRN78,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; other evidence: transgenic plants,,,YVS,33711077,PubMed,10.1371/journal.ppat.1009388,PLoS Pathog. 2021 Mar 12;17(3):e1009388,ddou@njau.edu.cn,CRN78 promoted Phytophthora capsici infection in Nicotiana benthamiana and enhanced P. sojae virulence on the host plant Glycine max by inhibiting plant H2O2 accumulation and immunity-related gene expression.,G Ai 2021,2021,1 gene,Ai-2021-A Phytophthora sojae CRN effector medi,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17927,PHI:11196,,no data found,,,,,,CRN78,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; other evidence: transgenic plants,,,YVS,33711077,PubMed,10.1371/journal.ppat.1009388,PLoS Pathog. 2021 Mar 12;17(3):e1009388,ddou@njau.edu.cn,CRN78 promoted Phytophthora capsici infection in Nicotiana benthamiana and enhanced P. sojae virulence on the host plant Glycine max by inhibiting plant H2O2 accumulation and immunity-related gene expression.,G Ai 2021,2021,1 gene,Ai-2021-A Phytophthora sojae CRN effector medi,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17928,PHI:11196,,no data found,,,,,,CRN78,,,,,,,67593,Phytophthora sojae,,race 2 strain P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,33711077,PubMed,10.1371/journal.ppat.1009388,PLoS Pathog. 2021 Mar 12;17(3):e1009388,ddou@njau.edu.cn,CRN78 promoted Phytophthora capsici infection in Nicotiana benthamiana and enhanced P. sojae virulence on the host plant Glycine max by inhibiting plant H2O2 accumulation and immunity-related gene expression.,G Ai 2021,2021,1 gene,Ai-2021-A Phytophthora sojae CRN effector medi,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17929,PHI:11197,,no data found,,,,,,mrvR (W903_RS09645),,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,chorioamnionitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,vagina,GntR-class transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33684178,PubMed,10.1371/journal.ppat.1009116,PLoS Pathog. 2021 Mar 8;17(3):e1009116,thomas.hooven@chp.edu,"The mrvR deletion mutant was able to cause persistent murine vaginal colonization, pregnant mice colonized with the mrvR deletion strain did not develop preterm labor despite consistent GBS invasion of the uterus and the fetoplacental units.",A N Dammann 2021,2021,1 gene,Dammann-2021-Genome-Wide fitness analysis of g,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17930,PHI:11197,,no data found,,,,,,mrvR (W903_RS09645),,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,chorioamnionitis,primates,9606,Homo sapiens (related: human),,,,amniotic fluid,GntR-class transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33684178,PubMed,10.1371/journal.ppat.1009116,PLoS Pathog. 2021 Mar 8;17(3):e1009116,thomas.hooven@chp.edu,"The mrvR deletion mutant was able to cause persistent murine vaginal colonization, pregnant mice colonized with the mrvR deletion strain did not develop preterm labor despite consistent GBS invasion of the uterus and the fetoplacental units.",A N Dammann 2021,2021,1 gene,Dammann-2021-Genome-Wide fitness analysis of g,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17931,PHI:11198,UniProt,A0A2G9KWN5,GenBank,PIN58679,,,MAFF212054,tssM,,,,,,,317,Pseudomonas syringae,1108972,pv. actinidiae strain M228,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),cv. Hongyang,,,leaf,type VI secretion system membrane subunit,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33679650,PubMed,10.3389/fmicb.2021.627785,Front Microbiol. 2021 Feb 19;12:627785,huanglili@nwsuaf.edu.cn,"The ability of bacterial competition, biofilm formation, hydrogen peroxide tolerance, and proteolytic activity were all weakened in the deletion mutants M228ΔT6SS, M228ΔtssM, and M228ΔtssJ.",N Wang 2021,2021,2 genes,Wang-2021-Role of the Type VI Secretion System,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17932,PHI:11199,UniProt,A0A2G9L1P2,GenBank,PIN60443,,,MAFF212054,tssJ,,,,,,,317,Pseudomonas syringae,1108972,pv. actinidiae strain M228,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),cv. Hongyang,,,leaf,type VI secretion system lipoprotein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33679650,PubMed,10.3389/fmicb.2021.627785,Front Microbiol. 2021 Feb 19;12:627785,huanglili@nwsuaf.edu.cn,"The ability of bacterial competition, biofilm formation, hydrogen peroxide tolerance, and proteolytic activity were all weakened in the deletion mutants M228ΔT6SS, M228ΔtssM, and M228ΔtssJ.",N Wang 2021,2021,2 genes,Wang-2021-Role of the Type VI Secretion System,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17933,PHI:11200,UniProt,J9VXE1,GenBank,AFR98898,,,H99,apn1 (CNAG_05468),chromosome 14,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,base excision repair apurinic/apyrimidinic (AP)-endonuclease,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate; sorbitol; caffeine; cadmium sulfate; sodium chloride; potassium chloride; menadione; sodium nitrite; hydrogen peroxide; hydroxyurea; methyl methane-sulfonate; ethyl methane-sulfonate; N-ethyl-N-nitrosourea; ethidium bromide; amphotericin B; methoxy-amine hydrochloride,sodium dodecyl sulfate: CHEBI:8984; sorbitol: CHEBI:30911; caffeine: CHEBI:27732; cadmium sulfate: CHEBI:50292; sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; menadione: CHEBI:28869; sodium nitrite: CHEBI:78870; hydrogen peroxide: CHEBI:16240; hydroxyurea: CHEBI:44423; methyl methane-sulfonate: CHEBI:25255; ethyl methane-sulfonate: CHEBI:23994; N-ethyl-N-nitrosourea: CHEBI:23995; ethidium bromide: CHEBI:4883; amphotericin B: CHEBI:2682; methoxy-amine hydrochloride: CAS:593-56-6,,,,,gene deletion: full; gene complementation,,,YVS,33673204,PubMed,10.3390/jof7020133,J Fungi (Basel). 2021 Feb 12;7(2):133,mpossas@unb.br,"The results demonstrated the involvement of the putative AP-endonucleases Apn1 and Apn2 in the cellular response to DNA damage induced by alkylation and by UV radiation, in melanin production, in tolerance to drugs and in virulence of C. neoformans in vivo.",R K M Oliveira 2021,2021,2 genes,Oliveira-2021-Base Excision Repair AP-Endonucl,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17934,PHI:11201,UniProt,J9VRX1,GenBank,AFR96998,,,H99,apn2 (CNAG_04268),chromosome 9,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,base excision repair apurinic/apyrimidinic (AP)-endonuclease,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate; sorbitol; caffeine; cadmium sulfate; sodium chloride; potassium chloride; menadione; sodium nitrite; hydrogen peroxide; hydroxyurea; methyl methane-sulfonate; ethyl methane-sulfonate; N-ethyl-N-nitrosourea; ethidium bromide; amphotericin B; methoxy-amine hydrochloride,sodium dodecyl sulfate: CHEBI:8984; sorbitol: CHEBI:30911; caffeine: CHEBI:27732; cadmium sulfate: CHEBI:50292; sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; menadione: CHEBI:28869; sodium nitrite: CHEBI:78870; hydrogen peroxide: CHEBI:16240; hydroxyurea: CHEBI:44423; methyl methane-sulfonate: CHEBI:25255; ethyl methane-sulfonate: CHEBI:23994; N-ethyl-N-nitrosourea: CHEBI:23995; ethidium bromide: CHEBI:4883; amphotericin B: CHEBI:2682; methoxy-amine hydrochloride: CAS:593-56-6,,,,,gene deletion: full; gene complementation,,,YVS,33673204,PubMed,10.3390/jof7020133,J Fungi (Basel). 2021 Feb 12;7(2):133,mpossas@unb.br,"The results demonstrated the involvement of the putative AP-endonucleases Apn1 and Apn2 in the cellular response to DNA damage induced by alkylation and by UV radiation, in melanin production, in tolerance to drugs and in virulence of C. neoformans in vivo.",R K M Oliveira 2021,2021,2 genes,Oliveira-2021-Base Excision Repair AP-Endonucl,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17935,PHI:11200,UniProt,J9VXE1,GenBank,AFR98898,,,H99,apn1 (CNAG_05468),chromosome 14,,,,,PHI:11201,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,base excision repair apurinic/apyrimidinic (AP)-endonuclease,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate; sorbitol; caffeine; cadmium sulfate; sodium chloride; potassium chloride; menadione; sodium nitrite; hydrogen peroxide; hydroxyurea; methyl methane-sulfonate; ethyl methane-sulfonate; N-ethyl-N-nitrosourea; ethidium bromide; amphotericin B; methoxy-amine hydrochloride,sodium dodecyl sulfate: CHEBI:8984; sorbitol: CHEBI:30911; caffeine: CHEBI:27732; cadmium sulfate: CHEBI:50292; sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; menadione: CHEBI:28869; sodium nitrite: CHEBI:78870; hydrogen peroxide: CHEBI:16240; hydroxyurea: CHEBI:44423; methyl methane-sulfonate: CHEBI:25255; ethyl methane-sulfonate: CHEBI:23994; N-ethyl-N-nitrosourea: CHEBI:23995; ethidium bromide: CHEBI:4883; amphotericin B: CHEBI:2682; methoxy-amine hydrochloride: CAS:593-56-6,,,,,gene deletion: full; gene complementation,,,YVS,33673204,PubMed,10.3390/jof7020133,J Fungi (Basel). 2021 Feb 12;7(2):133,mpossas@unb.br,"The results demonstrated the involvement of the putative AP-endonucleases Apn1 and Apn2 in the cellular response to DNA damage induced by alkylation and by UV radiation, in melanin production, in tolerance to drugs and in virulence of C. neoformans in vivo.",R K M Oliveira 2021,2021,2 genes,Oliveira-2021-Base Excision Repair AP-Endonucl,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17936,PHI:11201,UniProt,J9VRX1,GenBank,AFR96998,,,H99,apn2 (CNAG_04268),chromosome 9,,,,,PHI:11200,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,base excision repair apurinic/apyrimidinic (AP)-endonuclease,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate; sorbitol; caffeine; cadmium sulfate; sodium chloride; potassium chloride; menadione; sodium nitrite; hydrogen peroxide; hydroxyurea; methyl methane-sulfonate; ethyl methane-sulfonate; N-ethyl-N-nitrosourea; ethidium bromide; amphotericin B; methoxy-amine hydrochloride,sodium dodecyl sulfate: CHEBI:8984; sorbitol: CHEBI:30911; caffeine: CHEBI:27732; cadmium sulfate: CHEBI:50292; sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; menadione: CHEBI:28869; sodium nitrite: CHEBI:78870; hydrogen peroxide: CHEBI:16240; hydroxyurea: CHEBI:44423; methyl methane-sulfonate: CHEBI:25255; ethyl methane-sulfonate: CHEBI:23994; N-ethyl-N-nitrosourea: CHEBI:23995; ethidium bromide: CHEBI:4883; amphotericin B: CHEBI:2682; methoxy-amine hydrochloride: CAS:593-56-6,,,,,gene deletion: full; gene complementation,,,YVS,33673204,PubMed,10.3390/jof7020133,J Fungi (Basel). 2021 Feb 12;7(2):133,mpossas@unb.br,"The results demonstrated the involvement of the putative AP-endonucleases Apn1 and Apn2 in the cellular response to DNA damage induced by alkylation and by UV radiation, in melanin production, in tolerance to drugs and in virulence of C. neoformans in vivo.",R K M Oliveira 2021,2021,2 genes,Oliveira-2021-Base Excision Repair AP-Endonucl,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17937,PHI:11200,UniProt,J9VXE1,GenBank,AFR98898,,,H99,apn1 (CNAG_05468),chromosome 14,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,base excision repair apurinic/apyrimidinic (AP)-endonuclease,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate; sorbitol; caffeine; cadmium sulfate; sodium chloride; potassium chloride; menadione; sodium nitrite; hydrogen peroxide; hydroxyurea; methyl methane-sulfonate; ethyl methane-sulfonate; N-ethyl-N-nitrosourea; ethidium bromide; amphotericin B; methoxy-amine hydrochloride,sodium dodecyl sulfate: CHEBI:8984; sorbitol: CHEBI:30911; caffeine: CHEBI:27732; cadmium sulfate: CHEBI:50292; sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; menadione: CHEBI:28869; sodium nitrite: CHEBI:78870; hydrogen peroxide: CHEBI:16240; hydroxyurea: CHEBI:44423; methyl methane-sulfonate: CHEBI:25255; ethyl methane-sulfonate: CHEBI:23994; N-ethyl-N-nitrosourea: CHEBI:23995; ethidium bromide: CHEBI:4883; amphotericin B: CHEBI:2682; methoxy-amine hydrochloride: CAS:593-56-6,,,,,gene deletion: full; gene complementation,,,YVS,33673204,PubMed,10.3390/jof7020133,J Fungi (Basel). 2021 Feb 12;7(2):133,mpossas@unb.br,"The results demonstrated the involvement of the putative AP-endonucleases Apn1 and Apn2 in the cellular response to DNA damage induced by alkylation and by UV radiation, in melanin production, in tolerance to drugs and in virulence of C. neoformans in vivo.",R K M Oliveira 2021,2021,2 genes,Oliveira-2021-Base Excision Repair AP-Endonucl,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17938,PHI:11201,UniProt,J9VRX1,GenBank,AFR96998,,,H99,apn2 (CNAG_04268),chromosome 9,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,base excision repair apurinic/apyrimidinic (AP)-endonuclease,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate; sorbitol; caffeine; cadmium sulfate; sodium chloride; potassium chloride; menadione; sodium nitrite; hydrogen peroxide; hydroxyurea; methyl methane-sulfonate; ethyl methane-sulfonate; N-ethyl-N-nitrosourea; ethidium bromide; amphotericin B; methoxy-amine hydrochloride,sodium dodecyl sulfate: CHEBI:8984; sorbitol: CHEBI:30911; caffeine: CHEBI:27732; cadmium sulfate: CHEBI:50292; sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; menadione: CHEBI:28869; sodium nitrite: CHEBI:78870; hydrogen peroxide: CHEBI:16240; hydroxyurea: CHEBI:44423; methyl methane-sulfonate: CHEBI:25255; ethyl methane-sulfonate: CHEBI:23994; N-ethyl-N-nitrosourea: CHEBI:23995; ethidium bromide: CHEBI:4883; amphotericin B: CHEBI:2682; methoxy-amine hydrochloride: CAS:593-56-6,,,,,gene deletion: full; gene complementation,,,YVS,33673204,PubMed,10.3390/jof7020133,J Fungi (Basel). 2021 Feb 12;7(2):133,mpossas@unb.br,"The results demonstrated the involvement of the putative AP-endonucleases Apn1 and Apn2 in the cellular response to DNA damage induced by alkylation and by UV radiation, in melanin production, in tolerance to drugs and in virulence of C. neoformans in vivo.",R K M Oliveira 2021,2021,2 genes,Oliveira-2021-Base Excision Repair AP-Endonucl,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17939,PHI:11200,UniProt,J9VXE1,GenBank,AFR98898,,,H99,apn1 (CNAG_05468),chromosome 14,,,,,PHI:11201,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,base excision repair apurinic/apyrimidinic (AP)-endonuclease,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate; sorbitol; caffeine; cadmium sulfate; sodium chloride; potassium chloride; menadione; sodium nitrite; hydrogen peroxide; hydroxyurea; methyl methane-sulfonate; ethyl methane-sulfonate; N-ethyl-N-nitrosourea; ethidium bromide; amphotericin B; methoxy-amine hydrochloride,sodium dodecyl sulfate: CHEBI:8984; sorbitol: CHEBI:30911; caffeine: CHEBI:27732; cadmium sulfate: CHEBI:50292; sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; menadione: CHEBI:28869; sodium nitrite: CHEBI:78870; hydrogen peroxide: CHEBI:16240; hydroxyurea: CHEBI:44423; methyl methane-sulfonate: CHEBI:25255; ethyl methane-sulfonate: CHEBI:23994; N-ethyl-N-nitrosourea: CHEBI:23995; ethidium bromide: CHEBI:4883; amphotericin B: CHEBI:2682; methoxy-amine hydrochloride: CAS:593-56-6,,,,,gene deletion: full; gene complementation,,,YVS,33673204,PubMed,10.3390/jof7020133,J Fungi (Basel). 2021 Feb 12;7(2):133,mpossas@unb.br,"The results demonstrated the involvement of the putative AP-endonucleases Apn1 and Apn2 in the cellular response to DNA damage induced by alkylation and by UV radiation, in melanin production, in tolerance to drugs and in virulence of C. neoformans in vivo.",R K M Oliveira 2021,2021,2 genes,Oliveira-2021-Base Excision Repair AP-Endonucl,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17940,PHI:11201,UniProt,J9VRX1,GenBank,AFR96998,,,H99,apn2 (CNAG_04268),chromosome 9,,,,,PHI:11200,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,base excision repair apurinic/apyrimidinic (AP)-endonuclease,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate; sorbitol; caffeine; cadmium sulfate; sodium chloride; potassium chloride; menadione; sodium nitrite; hydrogen peroxide; hydroxyurea; methyl methane-sulfonate; ethyl methane-sulfonate; N-ethyl-N-nitrosourea; ethidium bromide; amphotericin B; methoxy-amine hydrochloride,sodium dodecyl sulfate: CHEBI:8984; sorbitol: CHEBI:30911; caffeine: CHEBI:27732; cadmium sulfate: CHEBI:50292; sodium chloride: CHEBI:26710; potassium chloride: CHEBI:32588; menadione: CHEBI:28869; sodium nitrite: CHEBI:78870; hydrogen peroxide: CHEBI:16240; hydroxyurea: CHEBI:44423; methyl methane-sulfonate: CHEBI:25255; ethyl methane-sulfonate: CHEBI:23994; N-ethyl-N-nitrosourea: CHEBI:23995; ethidium bromide: CHEBI:4883; amphotericin B: CHEBI:2682; methoxy-amine hydrochloride: CAS:593-56-6,,,,,gene deletion: full; gene complementation,,,YVS,33673204,PubMed,10.3390/jof7020133,J Fungi (Basel). 2021 Feb 12;7(2):133,mpossas@unb.br,"The results demonstrated the involvement of the putative AP-endonucleases Apn1 and Apn2 in the cellular response to DNA damage induced by alkylation and by UV radiation, in melanin production, in tolerance to drugs and in virulence of C. neoformans in vivo.",R K M Oliveira 2021,2021,2 genes,Oliveira-2021-Base Excision Repair AP-Endonucl,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17941,PHI:11202,UniProt,Q6NGP5,GenBank,CAE49991,,,NCTC13129,rnj (DIP1463),,,,,,,1717,Corynebacterium diphtheriae,257309,NCTC 13129,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,ribonuclease J,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33672886,PubMed,10.3390/microorganisms9020389,Microorganisms. 2021 Feb 14;9(2):389,htonthat@dentistry.ucla.edu,"The Δrnj mutant was severely attenuated in virulence in a Caenorhabditis elegans model of infection, while the FtsH-overexpressing and toxin-less strains exhibit full virulence as the wild-type strain.",T T Luong 2021,2021,4 genes,Luong-2021-Ribonuclease J-Mediated mRNA Turnov,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17942,PHI:11203,UniProt,Q6NF92,GenBank,CAE50533,,,NCTC13129,ftsH,,,,,,,1717,Corynebacterium diphtheriae,257309,NCTC 13129,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,ATP-dependent zinc metalloprotease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33672886,PubMed,10.3390/microorganisms9020389,Microorganisms. 2021 Feb 14;9(2):389,htonthat@dentistry.ucla.edu,"The Δrnj mutant was severely attenuated in virulence in a Caenorhabditis elegans model of infection, while the FtsH-overexpressing and toxin-less strains exhibit full virulence as the wild-type strain.",T T Luong 2021,2021,4 genes,Luong-2021-Ribonuclease J-Mediated mRNA Turnov,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17943,PHI:11204,UniProt,P0DJL7,GenBank,AAA23302,,,1030,dtxR,,,,,,,1717,Corynebacterium diphtheriae,257309,NCTC 13129,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,diphtheria toxin repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33672886,PubMed,10.3390/microorganisms9020389,Microorganisms. 2021 Feb 14;9(2):389,htonthat@dentistry.ucla.edu,"The Δrnj mutant was severely attenuated in virulence in a Caenorhabditis elegans model of infection, while the FtsH-overexpressing and toxin-less strains exhibit full virulence as the wild-type strain.",T T Luong 2021,2021,4 genes,Luong-2021-Ribonuclease J-Mediated mRNA Turnov,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17944,PHI:11205,UniProt,Q6NK15,GenBank,CAE48728,,,NCTC13129,tox,,,,,,,1717,Corynebacterium diphtheriae,257309,NCTC 13129,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,diphtheria toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33672886,PubMed,10.3390/microorganisms9020389,Microorganisms. 2021 Feb 14;9(2):389,htonthat@dentistry.ucla.edu,"The Δrnj mutant was severely attenuated in virulence in a Caenorhabditis elegans model of infection, while the FtsH-overexpressing and toxin-less strains exhibit full virulence as the wild-type strain.",T T Luong 2021,2021,4 genes,Luong-2021-Ribonuclease J-Mediated mRNA Turnov,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17945,PHI:11202,UniProt,Q6NGP5,GenBank,CAE49991,,,NCTC13129,rnj (DIP1463),,,,,,PHI:11204,1717,Corynebacterium diphtheriae,257309,NCTC 13129,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,ribonuclease J,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33672886,PubMed,10.3390/microorganisms9020389,Microorganisms. 2021 Feb 14;9(2):389,htonthat@dentistry.ucla.edu,"The Δrnj mutant was severely attenuated in virulence in a Caenorhabditis elegans model of infection, while the FtsH-overexpressing and toxin-less strains exhibit full virulence as the wild-type strain.",T T Luong 2021,2021,4 genes,Luong-2021-Ribonuclease J-Mediated mRNA Turnov,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17946,PHI:11204,UniProt,P0DJL7,GenBank,AAA23302,,,1030,dtxR,,,,,,PHI:11202,1717,Corynebacterium diphtheriae,257309,NCTC 13129,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,diphtheria toxin repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33672886,PubMed,10.3390/microorganisms9020389,Microorganisms. 2021 Feb 14;9(2):389,htonthat@dentistry.ucla.edu,"The Δrnj mutant was severely attenuated in virulence in a Caenorhabditis elegans model of infection, while the FtsH-overexpressing and toxin-less strains exhibit full virulence as the wild-type strain.",T T Luong 2021,2021,4 genes,Luong-2021-Ribonuclease J-Mediated mRNA Turnov,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17947,PHI:11206,,no data found,GenBank,ADX04121,,,1656-2,clpA,,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),J774.16 cell line,,,macrophage,ATP-dependent Clp protease ATP-binding subunit,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,33668542,PubMed,10.3390/pathogens10020204,Pathogens. 2021 Feb 13;10(2):204,LMartinez@dental.ufl.edu,"Clp-protease A. baumannii mutants exhibited decreased virulence in rodents, high phagocytic cell-mediated killing and reduced biofilm formation.",J C Belisario 2021,2021,3 genes,Belisario-2021-Acinetobacter baumannii Strains,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17948,PHI:11207,UniProt,V5VGK1,GenBank,AIL77961,,,AB030,clpB,,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),J774.16 cell line,,,macrophage,protein disaggregation chaperone,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,33668542,PubMed,10.3390/pathogens10020204,Pathogens. 2021 Feb 13;10(2):204,LMartinez@dental.ufl.edu,"Clp-protease A. baumannii mutants exhibited decreased virulence in rodents, high phagocytic cell-mediated killing and reduced biofilm formation.",J C Belisario 2021,2021,3 genes,Belisario-2021-Acinetobacter baumannii Strains,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17949,PHI:11208,UniProt,V5VCS6,GenBank,AIL81000,,,AB030,clpS,,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),J774.16 cell line,,,macrophage,ATP-dependent Clp protease adapter protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,33668542,PubMed,10.3390/pathogens10020204,Pathogens. 2021 Feb 13;10(2):204,LMartinez@dental.ufl.edu,"Clp-protease A. baumannii mutants exhibited decreased virulence in rodents, high phagocytic cell-mediated killing and reduced biofilm formation.",J C Belisario 2021,2021,3 genes,Belisario-2021-Acinetobacter baumannii Strains,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17950,PHI:11206,,no data found,GenBank,ADX04121,,,1656-2,clpA,,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; kidney,ATP-dependent Clp protease ATP-binding subunit,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,33668542,PubMed,10.3390/pathogens10020204,Pathogens. 2021 Feb 13;10(2):204,LMartinez@dental.ufl.edu,"Clp-protease A. baumannii mutants exhibited decreased virulence in rodents, high phagocytic cell-mediated killing and reduced biofilm formation.",J C Belisario 2021,2021,3 genes,Belisario-2021-Acinetobacter baumannii Strains,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17951,PHI:11207,UniProt,V5VGK1,GenBank,AIL77961,,,AB030,clpB,,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; kidney,protein disaggregation chaperone,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,33668542,PubMed,10.3390/pathogens10020204,Pathogens. 2021 Feb 13;10(2):204,LMartinez@dental.ufl.edu,"Clp-protease A. baumannii mutants exhibited decreased virulence in rodents, high phagocytic cell-mediated killing and reduced biofilm formation.",J C Belisario 2021,2021,3 genes,Belisario-2021-Acinetobacter baumannii Strains,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17952,PHI:11208,UniProt,V5VCS6,GenBank,AIL81000,,,AB030,clpS,,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; kidney,ATP-dependent Clp protease adapter protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,33668542,PubMed,10.3390/pathogens10020204,Pathogens. 2021 Feb 13;10(2):204,LMartinez@dental.ufl.edu,"Clp-protease A. baumannii mutants exhibited decreased virulence in rodents, high phagocytic cell-mediated killing and reduced biofilm formation.",J C Belisario 2021,2021,3 genes,Belisario-2021-Acinetobacter baumannii Strains,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17953,PHI:11209,UniProt,P0CL08,GenBank,AAL21755,,,LT2,hilD,,K293A and K294A,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain CA4787,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33617591,PubMed,10.1371/journal.ppat.1009357,PLoS Pathog. 2021 Feb 22;17(2):e1009357,altier@cornell.edu,"Mutation of key residues of HilD to alanine, predicted to interact with the DSF, prevented fatty acid binding, thereby ameliorated the repressive effect of c2-HDA on Salmonella invasion.",R Chowdhury 2021,2021,1 gene,Chowdhury-2021-A diffusible signal factor of t,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17954,PHI:11210,UniProt,A0A0D1E1T4,GenBank,KIS70044,,,521,cda7,chromosome 4,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,no,yes,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17955,PHI:11211,UniProt,A0A0D1E904,GenBank,KIS70875,,,521,cda1,chromosome 3,,,,,PHI:11212,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17956,PHI:11212,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda2,chromosome 1,,,,,PHI:11211,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17957,PHI:11213,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda3,chromosome 1,,,,,PHI:11214,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17958,PHI:11214,UniProt,A0A0D1EA24,GenBank,KIS71240,,,521,cda4,chromosome 2,,,,,PHI:11213,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17959,PHI:11213,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda3,chromosome 1,,,,,PHI:11214; PHI:11215; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17960,PHI:11214,UniProt,A0A0D1EA24,GenBank,KIS71240,,,521,cda4,chromosome 2,,,,,PHI:11213; PHI:11215; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17961,PHI:11215,UniProt,A0A0D1CW71,GenBank,KIS70623,,,521,cda5,chromosome 3,,,,,PHI:11213; PHI:11214; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17962,PHI:11216,UniProt,A0A0D1E904,GenBank,KIS70875,,,521,cda6,chromosome 3,,,,,PHI:11213; PHI:11214; PHI:11215,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17963,PHI:11212,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda2,chromosome 1,,,,,PHI:11213; PHI:11214,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17964,PHI:11213,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda3,chromosome 1,,,,,PHI:11212; PHI:11214,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17965,PHI:11214,UniProt,A0A0D1EA24,GenBank,KIS71240,,,521,cda4,chromosome 2,,,,,PHI:11212; PHI:11213,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17966,PHI:11212,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda2,chromosome 1,,,,,PHI:11213; PHI:11214; PHI:11215; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,yes,yes,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17967,PHI:11213,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda3,chromosome 1,,,,,PHI:11212; PHI:11214; PHI:11215; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,yes,yes,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17968,PHI:11214,UniProt,A0A0D1EA24,GenBank,KIS71240,,,521,cda4,chromosome 2,,,,,PHI:11212; PHI:11213; PHI:11215; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,yes,yes,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17969,PHI:11215,UniProt,A0A0D1CW71,GenBank,KIS70623,,,521,cda5,chromosome 3,,,,,PHI:11212; PHI:11213; PHI:11214; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,yes,yes,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17970,PHI:11216,UniProt,A0A0D1E904,GenBank,KIS70875,,,521,cda6,chromosome 3,,,,,PHI:11212; PHI:11213; PHI:11214; PHI:11215,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,yes,yes,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17971,PHI:11211,UniProt,A0A0D1E904,GenBank,KIS70875,,,521,cda1,chromosome 3,,,,,PHI:11213; PHI:11214; PHI:11215; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17972,PHI:11213,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda3,chromosome 1,,,,,PHI:11211; PHI:11214; PHI:11215; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17973,PHI:11214,UniProt,A0A0D1EA24,GenBank,KIS71240,,,521,cda4,chromosome 2,,,,,PHI:11211; PHI:11213; PHI:11215; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17974,PHI:11215,UniProt,A0A0D1CW71,GenBank,KIS70623,,,521,cda5,chromosome 3,,,,,PHI:11211; PHI:11213; PHI:11214; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17975,PHI:11216,UniProt,A0A0D1E904,GenBank,KIS70875,,,521,cda6,chromosome 3,,,,,PHI:11211; PHI:11213; PHI:11214; PHI:11215,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17976,PHI:11212,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda2,chromosome 1,,,,,PHI:11213; PHI:11214; PHI:11215; PHI:11216; PHI:11210,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17977,PHI:11213,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda3,chromosome 1,,,,,PHI:11212; PHI:11214; PHI:11215; PHI:11216; PHI:11210,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17978,PHI:11214,UniProt,A0A0D1EA24,GenBank,KIS71240,,,521,cda4,chromosome 2,,,,,PHI:11212; PHI:11213; PHI:11215; PHI:11216; PHI:11210,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17979,PHI:11215,UniProt,A0A0D1CW71,GenBank,KIS70623,,,521,cda5,chromosome 3,,,,,PHI:11212; PHI:11213; PHI:11214; PHI:11216; PHI:11210,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17980,PHI:11216,UniProt,A0A0D1E904,GenBank,KIS70875,,,521,cda6,chromosome 3,,,,,PHI:11212; PHI:11213; PHI:11214; PHI:11215; PHI:11210,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17981,PHI:11210,UniProt,A0A0D1E1T4,GenBank,KIS70044,,,521,cda7,chromosome 4,,,,,PHI:11212; PHI:11213; PHI:11214; PHI:11215; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17982,PHI:11211,UniProt,A0A0D1E904,GenBank,KIS70875,,,521,cda1,chromosome 3,,,,,PHI:11213; PHI:11214; PHI:11215; PHI:11216; PHI:11210,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17983,PHI:11213,UniProt,A0A0D1D1F2,GenBank,KIS72223,,,521,cda3,chromosome 1,,,,,PHI:11211; PHI:11214; PHI:11215; PHI:11216; PHI:11210,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17984,PHI:11214,UniProt,A0A0D1EA24,GenBank,KIS71240,,,521,cda4,chromosome 2,,,,,PHI:11211; PHI:11213; PHI:11215; PHI:11216; PHI:11210,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17985,PHI:11215,UniProt,A0A0D1CW71,GenBank,KIS70623,,,521,cda5,chromosome 3,,,,,PHI:11211; PHI:11213; PHI:11214; PHI:11216; PHI:11210,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17986,PHI:11216,UniProt,A0A0D1E904,GenBank,KIS70875,,,521,cda6,chromosome 3,,,,,PHI:11211; PHI:11213; PHI:11214; PHI:11215; PHI:11210,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17987,PHI:11210,UniProt,A0A0D1E1T4,GenBank,KIS70044,,,521,cda7,chromosome 4,,,,,PHI:11211; PHI:11213; PHI:11214; PHI:11215; PHI:11216,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; calcofluor white,H2O2: CHEBI:16240; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33653886,PubMed,10.1128/mBio.03419-20,mBio. 2021 Mar 2;12(2):e03419-20,kahmann@mpi-marburg.mpg.de,Single as well as multiple cda mutants were generated and revealed a virulence defect for mutants lacking cda7.,Y S Rizzi 2021,2021,7 genes,Rizzi-2021-Chitosan and Chitin Deacetylase Act,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17988,PHI:11217,UniProt,Q04971,GenBank,CAA47990,,,Ty2,tviA,,Mutational inhibition of the RNAT in the 5' UTR of tviA,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,Vi polysaccharide biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33651854,PubMed,10.1371/journal.ppat.1009345,PLoS Pathog. 2021 Mar 2;17(3):e1009345,dmonack@stanford.edu,"Mutational inhibition of the RNAT in S.Typhi caused aberrant virulence factor expression, leading to enhanced innate immune responses during infection.",S M Brewer 2021,2021,1 gene,Brewer-2021-A Salmonella Typhi RNA thermosenso,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17989,PHI:11217,UniProt,Q04971,GenBank,CAA47990,,,Ty2,tviA,,Mutational inhibition of the RNAT in the 5' UTR of tviA,,,,,28901,Salmonella enterica,209261,subsp. enterica serovar Typhi strain Ty2,salmonellosis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colonic epithelial cell,Vi polysaccharide biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33651854,PubMed,10.1371/journal.ppat.1009345,PLoS Pathog. 2021 Mar 2;17(3):e1009345,dmonack@stanford.edu,"Mutational inhibition of the RNAT in S.Typhi caused aberrant virulence factor expression, leading to enhanced innate immune responses during infection.",S M Brewer 2021,2021,1 gene,Brewer-2021-A Salmonella Typhi RNA thermosenso,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17990,PHI:11218,UniProt,Q4QIZ0,GenBank,CAJ02133,,,Friedlin,PRMT7,,,,,,,5664,Leishmania major,,CC1,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,ear,protein methyltransferase 7,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33651805,PubMed,10.1371/journal.pntd.0009230,PLoS Negl Trop Dis. 2021 Mar 2;15(3):e0009230,akcruz@fmrp.usp.br,Lesion formation caused by LmjPRMT7 knockout parasites was associated with an exacerbated inflammatory reaction in the tissue correlated with an excessive neutrophil recruitment.,J Alcoforado Diniz 2021,2021,1 gene,Alcoforado Dini-2021-Protein methyltransferase,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17991,PHI:11218,UniProt,Q4QIZ0,GenBank,CAJ02133,,,Friedlin,PRMT7,,,,,,,5664,Leishmania major,,CC1,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,ear,protein methyltransferase 7,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33651805,PubMed,10.1371/journal.pntd.0009230,PLoS Negl Trop Dis. 2021 Mar 2;15(3):e0009230,akcruz@fmrp.usp.br,Lesion formation caused by LmjPRMT7 knockout parasites was associated with an exacerbated inflammatory reaction in the tissue correlated with an excessive neutrophil recruitment.,J Alcoforado Diniz 2021,2021,1 gene,Alcoforado Dini-2021-Protein methyltransferase,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17992,PHI:11218,UniProt,Q4QIZ0,GenBank,CAJ02133,,,Friedlin,PRMT7,,,,,,,5664,Leishmania major,,CC1,leishmaniasis,flies,7200,Lutzomyia longipalpis (no common name found),,,,,protein methyltransferase 7,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33651805,PubMed,10.1371/journal.pntd.0009230,PLoS Negl Trop Dis. 2021 Mar 2;15(3):e0009230,akcruz@fmrp.usp.br,Lesion formation caused by LmjPRMT7 knockout parasites was associated with an exacerbated inflammatory reaction in the tissue correlated with an excessive neutrophil recruitment.,J Alcoforado Diniz 2021,2021,1 gene,Alcoforado Dini-2021-Protein methyltransferase,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17993,PHI:11219,UniProt,Q7CR17,GenBank,AAL19427,,,LT2,hha,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SB300,salmonellosis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,HCT-116 cell,hemolysin expression-modulating protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33651227,PubMed,10.1007/s10565-021-09587-z,Cell Biol Toxicol. 2021 Mar 2,msuar@kiitbiotech.ac.in,"Deletion of hha and tomB genes displayed impaired cell adhesion, invasion, and uptake.",P Paul 2021,2021,2 genes,Paul-2021-The Hha-TomB toxin-antitoxin module,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17994,PHI:11219,UniProt,Q7CR17,GenBank,AAL19427,,,LT2,hha,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SB300,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,hemolysin expression-modulating protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33651227,PubMed,10.1007/s10565-021-09587-z,Cell Biol Toxicol. 2021 Mar 2,msuar@kiitbiotech.ac.in,"Deletion of hha and tomB genes displayed impaired cell adhesion, invasion, and uptake.",P Paul 2021,2021,2 genes,Paul-2021-The Hha-TomB toxin-antitoxin module,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17995,PHI:11220,UniProt,A0A0F7J4C9,GenBank,AKH06147,,,YU39,tomB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SB300,salmonellosis,primates,9606,Homo sapiens (related: human),HCT 116 cell line,,,HCT-116 cell,Hha toxicity attenuator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33651227,PubMed,10.1007/s10565-021-09587-z,Cell Biol Toxicol. 2021 Mar 2,msuar@kiitbiotech.ac.in,"Deletion of hha and tomB genes displayed impaired cell adhesion, invasion, and uptake.",P Paul 2021,2021,2 genes,Paul-2021-The Hha-TomB toxin-antitoxin module,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17996,PHI:11220,UniProt,A0A0F7J4C9,GenBank,AKH06147,,,YU39,tomB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SB300,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,Hha toxicity attenuator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33651227,PubMed,10.1007/s10565-021-09587-z,Cell Biol Toxicol. 2021 Mar 2,msuar@kiitbiotech.ac.in,"Deletion of hha and tomB genes displayed impaired cell adhesion, invasion, and uptake.",P Paul 2021,2021,2 genes,Paul-2021-The Hha-TomB toxin-antitoxin module,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17997,PHI:11219,UniProt,Q7CR17,GenBank,AAL19427,,,LT2,hha,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SB300,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node; cecum,hemolysin expression-modulating protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33651227,PubMed,10.1007/s10565-021-09587-z,Cell Biol Toxicol. 2021 Mar 2,msuar@kiitbiotech.ac.in,"Deletion of hha and tomB genes displayed impaired cell adhesion, invasion, and uptake.",P Paul 2021,2021,2 genes,Paul-2021-The Hha-TomB toxin-antitoxin module,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17998,PHI:11220,UniProt,A0A0F7J4C9,GenBank,AKH06147,,,YU39,tomB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SB300,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; mesenteric lymph node; cecum,Hha toxicity attenuator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33651227,PubMed,10.1007/s10565-021-09587-z,Cell Biol Toxicol. 2021 Mar 2,msuar@kiitbiotech.ac.in,"Deletion of hha and tomB genes displayed impaired cell adhesion, invasion, and uptake.",P Paul 2021,2021,2 genes,Paul-2021-The Hha-TomB toxin-antitoxin module,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 17999,PHI:11221,UniProt,Q2FXC2,GenBank,ABD31004,,,NCTC 8325,splA,,,,,,PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226; PHI:11227; PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18000,PHI:11222,UniProt,Q2FXC3,GenBank,ABD31003,,,NCTC 8325,splB,,,,,,PHI:11221; PHI:11223; PHI:11224; PHI:11225; PHI:11226; PHI:11227; PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18001,PHI:11223,UniProt,Q2FXC4,GenBank,ABD31002,,,NCTC 8325,splC,,,,,,PHI:11221; PHI:11222; PHI:11224; PHI:11225; PHI:11226; PHI:11227; PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18002,PHI:11224,UniProt,Q2FXC5,GenBank,ABD31001,,,NCTC 8325,splD,,,,,,PHI:11221; PHI:11222; PHI:11223; PHI:11225; PHI:11226; PHI:11227; PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18003,PHI:11225,UniProt,Q2FXC7,GenBank,ABD30999,,,NCTC 8325,splE,,,,,,PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11226; PHI:11227; PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18004,PHI:11226,UniProt,Q2FXC8,GenBank,ABD30998,,,NCTC 8325,splF,,,,,,PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11227; PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18005,PHI:11227,UniProt,Q2FZL2,GenBank,ABD30113,,,NCTC 8325,sspA,,,,,,PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226; PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain B,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18006,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226; PHI:11227; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18007,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpA,,,,,,PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226; PHI:11227; PHI:11228,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18008,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11230; PHI:11229; PHI:11227,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18009,PHI:11230,UniProt,Q2FZL3,GenBank,ABD30112,,,NCTC 8325,sspB,,,,,,PHI:11228; PHI:11229; PHI:11227,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,glutamyl endopeptidase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18010,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpA,,,,,,PHI:11228; PHI:11230; PHI:11227,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18011,PHI:11227,UniProt,Q2FZL2,GenBank,ABD30113,,,NCTC 8325,sspA,,,,,,PHI:11228; PHI:11230; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain B,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18012,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11230; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18013,PHI:11230,UniProt,Q2FZL3,GenBank,ABD30112,,,NCTC 8325,sspB,,,,,,PHI:11228; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,glutamyl endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18014,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpA,,,,,,PHI:11228; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18015,PHI:11221,UniProt,Q2FXC2,GenBank,ABD31004,,,NCTC 8325,splA,,,,,,PHI:11228; PHI:11230; PHI:11229; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18016,PHI:11222,UniProt,Q2FXC3,GenBank,ABD31003,,,NCTC 8325,splB,,,,,,PHI:11228; PHI:11230; PHI:11229; PHI:11221; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18017,PHI:11223,UniProt,Q2FXC4,GenBank,ABD31002,,,NCTC 8325,splC,,,,,,PHI:11228; PHI:11230; PHI:11229; PHI:11221; PHI:11222; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18018,PHI:11224,UniProt,Q2FXC5,GenBank,ABD31001,,,NCTC 8325,splD,,,,,,PHI:11228; PHI:11230; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18019,PHI:11225,UniProt,Q2FXC7,GenBank,ABD30999,,,NCTC 8325,splE,,,,,,PHI:11228; PHI:11230; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18020,PHI:11226,UniProt,Q2FXC8,GenBank,ABD30998,,,NCTC 8325,splF,,,,,,PHI:11228; PHI:11230; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18021,PHI:11227,UniProt,Q2FZL2,GenBank,ABD30113,,,NCTC 8325,sspA,,,,,,PHI:11230; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18022,PHI:11230,UniProt,Q2FZL3,GenBank,ABD30112,,,NCTC 8325,sspB,,,,,,PHI:11227; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,glutamyl endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18023,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpA,,,,,,PHI:11227; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18024,PHI:11221,UniProt,Q2FXC2,GenBank,ABD31004,,,NCTC 8325,splA,,,,,,PHI:11227; PHI:11230; PHI:11229; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18025,PHI:11222,UniProt,Q2FXC3,GenBank,ABD31003,,,NCTC 8325,splB,,,,,,PHI:11227; PHI:11230; PHI:11229; PHI:11221; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18026,PHI:11223,UniProt,Q2FXC4,GenBank,ABD31002,,,NCTC 8325,splC,,,,,,PHI:11227; PHI:11230; PHI:11229; PHI:11221; PHI:11222; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18027,PHI:11224,UniProt,Q2FXC5,GenBank,ABD31001,,,NCTC 8325,splD,,,,,,PHI:11227; PHI:11230; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18028,PHI:11225,UniProt,Q2FXC7,GenBank,ABD30999,,,NCTC 8325,splE,,,,,,PHI:11227; PHI:11230; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18029,PHI:11226,UniProt,Q2FXC8,GenBank,ABD30998,,,NCTC 8325,splF,,,,,,PHI:11227; PHI:11230; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18030,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11227; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18031,PHI:11227,UniProt,Q2FZL2,GenBank,ABD30113,,,NCTC 8325,sspA,,,,,,PHI:11228; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain B,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18032,PHI:11230,UniProt,Q2FZL3,GenBank,ABD30112,,,NCTC 8325,sspB,,,,,,PHI:11228; PHI:11227; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,glutamyl endopeptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18033,PHI:11221,UniProt,Q2FXC2,GenBank,ABD31004,,,NCTC 8325,splA,,,,,,PHI:11228; PHI:11227; PHI:11230; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18034,PHI:11222,UniProt,Q2FXC3,GenBank,ABD31003,,,NCTC 8325,splB,,,,,,PHI:11228; PHI:11227; PHI:11230; PHI:11221; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18035,PHI:11223,UniProt,Q2FXC4,GenBank,ABD31002,,,NCTC 8325,splC,,,,,,PHI:11228; PHI:11227; PHI:11230; PHI:11221; PHI:11222; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18036,PHI:11224,UniProt,Q2FXC5,GenBank,ABD31001,,,NCTC 8325,splD,,,,,,PHI:11228; PHI:11227; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18037,PHI:11225,UniProt,Q2FXC7,GenBank,ABD30999,,,NCTC 8325,splE,,,,,,PHI:11228; PHI:11227; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18038,PHI:11226,UniProt,Q2FXC8,GenBank,ABD30998,,,NCTC 8325,splF,,,,,,PHI:11228; PHI:11227; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18039,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18040,PHI:11230,UniProt,Q2FZL3,GenBank,ABD30112,,,NCTC 8325,sspB,,,,,,PHI:11228; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,glutamyl endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18041,PHI:11221,UniProt,Q2FXC2,GenBank,ABD31004,,,NCTC 8325,splA,,,,,,PHI:11228; PHI:11230; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18042,PHI:11222,UniProt,Q2FXC3,GenBank,ABD31003,,,NCTC 8325,splB,,,,,,PHI:11228; PHI:11230; PHI:11221; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18043,PHI:11223,UniProt,Q2FXC4,GenBank,ABD31002,,,NCTC 8325,splC,,,,,,PHI:11228; PHI:11230; PHI:11221; PHI:11222; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18044,PHI:11224,UniProt,Q2FXC5,GenBank,ABD31001,,,NCTC 8325,splD,,,,,,PHI:11228; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18045,PHI:11225,UniProt,Q2FXC7,GenBank,ABD30999,,,NCTC 8325,splE,,,,,,PHI:11228; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18046,PHI:11226,UniProt,Q2FXC8,GenBank,ABD30998,,,NCTC 8325,splF,,,,,,PHI:11228; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18047,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11227; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18048,PHI:11227,UniProt,Q2FZL2,GenBank,ABD30113,,,NCTC 8325,sspA,,,,,,PHI:11228; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18049,PHI:11221,UniProt,Q2FXC2,GenBank,ABD31004,,,NCTC 8325,splA,,,,,,PHI:11228; PHI:11227; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18050,PHI:11222,UniProt,Q2FXC3,GenBank,ABD31003,,,NCTC 8325,splB,,,,,,PHI:11228; PHI:11227; PHI:11221; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18051,PHI:11223,UniProt,Q2FXC4,GenBank,ABD31002,,,NCTC 8325,splC,,,,,,PHI:11228; PHI:11227; PHI:11221; PHI:11222; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18052,PHI:11224,UniProt,Q2FXC5,GenBank,ABD31001,,,NCTC 8325,splD,,,,,,PHI:11228; PHI:11227; PHI:11221; PHI:11222; PHI:11223; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18053,PHI:11225,UniProt,Q2FXC7,GenBank,ABD30999,,,NCTC 8325,splE,,,,,,PHI:11228; PHI:11227; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18054,PHI:11226,UniProt,Q2FXC8,GenBank,ABD30998,,,NCTC 8325,splF,,,,,,PHI:11228; PHI:11227; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18055,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11227; PHI:11230,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18056,PHI:11227,UniProt,Q2FZL2,GenBank,ABD30113,,,NCTC 8325,sspA,,,,,,PHI:11228; PHI:11230,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18057,PHI:11230,UniProt,Q2FZL3,GenBank,ABD30112,,,NCTC 8325,sspB,,,,,,PHI:11228; PHI:11227,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,glutamyl endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18058,PHI:11227,UniProt,Q2FZL2,GenBank,ABD30113,,,NCTC 8325,sspA,,,,,,PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18059,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpA,,,,,,PHI:11227; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18060,PHI:11221,UniProt,Q2FXC2,GenBank,ABD31004,,,NCTC 8325,splA,,,,,,PHI:11227; PHI:11229; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18061,PHI:11222,UniProt,Q2FXC3,GenBank,ABD31003,,,NCTC 8325,splB,,,,,,PHI:11227; PHI:11229; PHI:11221; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18062,PHI:11223,UniProt,Q2FXC4,GenBank,ABD31002,,,NCTC 8325,splC,,,,,,PHI:11227; PHI:11229; PHI:11221; PHI:11222; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18063,PHI:11224,UniProt,Q2FXC5,GenBank,ABD31001,,,NCTC 8325,splD,,,,,,PHI:11227; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18064,PHI:11225,UniProt,Q2FXC7,GenBank,ABD30999,,,NCTC 8325,splE,,,,,,PHI:11227; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18065,PHI:11226,UniProt,Q2FXC8,GenBank,ABD30998,,,NCTC 8325,splF,,,,,,PHI:11227; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18066,PHI:11227,UniProt,Q2FZL2,GenBank,ABD30113,,,NCTC 8325,sspA,,,,,,PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18067,PHI:11230,UniProt,Q2FZL3,GenBank,ABD30112,,,NCTC 8325,sspB,,,,,,PHI:11227; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,glutamyl endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18068,PHI:11221,UniProt,Q2FXC2,GenBank,ABD31004,,,NCTC 8325,splA,,,,,,PHI:11227; PHI:11230; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18069,PHI:11222,UniProt,Q2FXC3,GenBank,ABD31003,,,NCTC 8325,splB,,,,,,PHI:11227; PHI:11230; PHI:11221; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18070,PHI:11223,UniProt,Q2FXC4,GenBank,ABD31002,,,NCTC 8325,splC,,,,,,PHI:11227; PHI:11230; PHI:11221; PHI:11222; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18071,PHI:11224,UniProt,Q2FXC5,GenBank,ABD31001,,,NCTC 8325,splD,,,,,,PHI:11227; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18072,PHI:11225,UniProt,Q2FXC7,GenBank,ABD30999,,,NCTC 8325,splE,,,,,,PHI:11227; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18073,PHI:11226,UniProt,Q2FXC8,GenBank,ABD30998,,,NCTC 8325,splF,,,,,,PHI:11227; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18074,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpA,,,,,,PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18075,PHI:11230,UniProt,Q2FZL3,GenBank,ABD30112,,,NCTC 8325,sspB,,,,,,PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,glutamyl endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18076,PHI:11221,UniProt,Q2FXC2,GenBank,ABD31004,,,NCTC 8325,splA,,,,,,PHI:11229; PHI:11230; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18077,PHI:11222,UniProt,Q2FXC3,GenBank,ABD31003,,,NCTC 8325,splB,,,,,,PHI:11229; PHI:11230; PHI:11221; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18078,PHI:11223,UniProt,Q2FXC4,GenBank,ABD31002,,,NCTC 8325,splC,,,,,,PHI:11229; PHI:11230; PHI:11221; PHI:11222; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18079,PHI:11224,UniProt,Q2FXC5,GenBank,ABD31001,,,NCTC 8325,splD,,,,,,PHI:11229; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18080,PHI:11225,UniProt,Q2FXC7,GenBank,ABD30999,,,NCTC 8325,splE,,,,,,PHI:11229; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18081,PHI:11226,UniProt,Q2FXC8,GenBank,ABD30998,,,NCTC 8325,splF,,,,,,PHI:11229; PHI:11230; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18082,PHI:11227,UniProt,Q2FZL2,GenBank,ABD30113,,,NCTC 8325,sspA,,,,,,PHI:11230; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18083,PHI:11230,UniProt,Q2FZL3,GenBank,ABD30112,,,NCTC 8325,sspB,,,,,,PHI:11227; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,glutamyl endopeptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18084,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpA,,,,,,PHI:11227; PHI:11230,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18085,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11229; PHI:11230,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18086,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpa,,,,,,PHI:11228; PHI:11230,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18087,PHI:11230,UniProt,Q2FZL3,GenBank,ABD30112,,,NCTC 8325,sspB,,,,,,PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,glutamyl endopeptidase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18088,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11229; PHI:11227,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18089,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpa,,,,,,PHI:11228; PHI:11227,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18090,PHI:11227,UniProt,Q2FZL2,GenBank,ABD30113,,,NCTC 8325,sspA,,,,,,PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain B,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18091,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18092,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpa,,,,,,PHI:11228; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18093,PHI:11221,UniProt,Q2FXC2,GenBank,ABD31004,,,NCTC 8325,splA,,,,,,PHI:11228; PHI:11229; PHI:11222; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18094,PHI:11222,UniProt,Q2FXC3,GenBank,ABD31003,,,NCTC 8325,splB,,,,,,PHI:11228; PHI:11229; PHI:11221; PHI:11223; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18095,PHI:11223,UniProt,Q2FXC4,GenBank,ABD31002,,,NCTC 8325,splC,,,,,,PHI:11228; PHI:11229; PHI:11221; PHI:11222; PHI:11224; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18096,PHI:11224,UniProt,Q2FXC5,GenBank,ABD31001,,,NCTC 8325,splD,,,,,,PHI:11228; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11225; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18097,PHI:11225,UniProt,Q2FXC7,GenBank,ABD30999,,,NCTC 8325,splE,,,,,,PHI:11228; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11226,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18098,PHI:11226,UniProt,Q2FXC8,GenBank,ABD30998,,,NCTC 8325,splF,,,,,,PHI:11228; PHI:11229; PHI:11221; PHI:11222; PHI:11223; PHI:11224; PHI:11225,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,serine protease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18099,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11229; PHI:11231,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18100,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpa,,,,,,PHI:11228; PHI:11231,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18101,PHI:11231,UniProt,A0A0H2XED4,GenBank,ABD20642,,,USA300_FPR3757,SAUSA300_0964,,,,,,PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,chitinase-related protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18102,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11229; PHI:11232,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18103,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpa,,,,,,PHI:11228; PHI:11232,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18104,PHI:11232,UniProt,no data found,GenBank,AGU55611,,,6850,lukA,,,,,,PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,leukocidin subunit,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18105,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18106,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpa,,,,,,PHI:11228,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18107,PHI:11228,UniProt,P81177,GenBank,CAB59567,,,V8-BC10,aur,,,,,,PHI:11229; PHI:11233,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,zinc metalloproteinase aureolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18108,PHI:11229,UniProt,P65826,GenBank,BAB42995,,,N315,scpa,,,,,,PHI:11228; PHI:11233,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,staphopain A,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18109,PHI:11233,UniProt,Q93CC5,GenBank,AF410775_23,,,COL,sek,,,,,,PHI:11228; PHI:11229,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,enterotoxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33622717,PubMed,10.1128/mBio.03288-20,mBio. 2021 Feb 23;12(1):e03288-20,shaw@usf.edu,Well-known toxin (LukA) and an entirely novel secreted element (SAUSA300_0964) were the leading contributors to deadly infections observed in protease-lacking strains.,B D Gimza 2021,2021,13 genes,Gimza-2021-Unraveling the Impact of Secreted P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18110,PHI:11234,UniProt,A4VWH9,GenBank,ABP90468,,,05ZYH33,Eno,,,,,,,1307,Streptococcus suis,,CVCC606,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: Pig),PBMECs,,,brain microvascular endothelial cell line,enolase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,YVS,33618766,PubMed,10.1186/s13567-020-00887-6,Vet Res. 2021 Feb 22;52(1):30,leiliancheng@163.com,Eno played an important role in SS2 adhesion to PBMECs and penetration into the BBB.,H Liu 2021,2021,1 gene,Liu-2021-Streptococcus suis serotype 2 enolase,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18111,PHI:11234,UniProt,A4VWH9,GenBank,ABP90468,,,05ZYH33,Eno,,,,,,,1307,Streptococcus suis,,CVCC606,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),ICR,,,brain,enolase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host,,,YVS,33618766,PubMed,10.1186/s13567-020-00887-6,Vet Res. 2021 Feb 22;52(1):30,leiliancheng@163.com,Eno played an important role in SS2 adhesion to PBMECs and penetration into the BBB.,H Liu 2021,2021,1 gene,Liu-2021-Streptococcus suis serotype 2 enolase,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18112,PHI:11235,UniProt,A0A393IB40,GenBank,EAA0288636,,,CFSAN061633,YjbH,,,,spxA1,UniProt: no data found; GenBank: no data found,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,liver; spleen,putative thioredoxin family oxidoreductase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; diamide; cadmium chloride; copper chloride,H2O22: CHEBI:16240; diamide: CHEBI:48958; cadmium chloride: CHEBI:35456; copper(II) chloride: CHEBI:49553,,,,,gene deletion: full; gene complementation,,,YVS,33573432,PubMed,10.1080/19490976.2021.1884517,Gut Microbes. 2021 Jan-Dec;13(1):1-19,songhh@zafu.edu.cn,The deletion of YjbH compromised the oxidative stress tolerance of L. monocytogenes.,C Cheng 2021,2021,1 gene,Cheng-2021-YjbH mediates the oxidative stress,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18113,PHI:11235,UniProt,A0A393IB40,GenBank,EAA0288636,,,CFSAN061633,YjbH,,,,spxA1,UniProt: no data found; GenBank: no data found,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),L929 cell line,,,fibroblast,putative thioredoxin family oxidoreductase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; diamide; cadmium chloride; copper chloride,H2O22: CHEBI:16240; diamide: CHEBI:48958; cadmium chloride: CHEBI:35456; copper(II) chloride: CHEBI:49553,,,,,gene deletion: full; gene complementation,,,YVS,33573432,PubMed,10.1080/19490976.2021.1884517,Gut Microbes. 2021 Jan-Dec;13(1):1-19,songhh@zafu.edu.cn,The deletion of YjbH compromised the oxidative stress tolerance of L. monocytogenes.,C Cheng 2021,2021,1 gene,Cheng-2021-YjbH mediates the oxidative stress,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18114,PHI:11235,UniProt,A0A393IB40,GenBank,EAA0288636,,,CFSAN061633,YjbH,,,,spxA1,UniProt: no data found; GenBank: no data found,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative thioredoxin family oxidoreductase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; diamide; cadmium chloride; copper chloride,H2O22: CHEBI:16240; diamide: CHEBI:48958; cadmium chloride: CHEBI:35456; copper(II) chloride: CHEBI:49553,,,,,gene deletion: full; gene complementation,,,YVS,33573432,PubMed,10.1080/19490976.2021.1884517,Gut Microbes. 2021 Jan-Dec;13(1):1-19,songhh@zafu.edu.cn,The deletion of YjbH compromised the oxidative stress tolerance of L. monocytogenes.,C Cheng 2021,2021,1 gene,Cheng-2021-YjbH mediates the oxidative stress,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18115,PHI:11236,,no data found,,,,,,nox1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,NADPH oxidase,,,,increased virulence (hypervirulence),,,no,no,,,,wild type,,no,caspofungin,caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,33570748,PubMed,10.1111/nph.17268,New Phytol. 2021 May;230(4):1578-1593,nick.talbot@tsl.ac.uk,The Δnox1 mutant showed increased resistance to chitosan and was only slightly affected by chitosan at very high doses.,F Lopez-Moya 2021,2021,2 genes,Lopez-Moya-2021-Chitosan inhibits septin-media,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18116,PHI:11237,,no data found,,,,,,nox2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,NADPH oxidase,,,,unaffected pathogenicity,,,yes,yes,,,,reduced,,no,caspofungin,caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,33570748,PubMed,10.1111/nph.17268,New Phytol. 2021 May;230(4):1578-1593,nick.talbot@tsl.ac.uk,The Δnox1 mutant showed increased resistance to chitosan and was only slightly affected by chitosan at very high doses.,F Lopez-Moya 2021,2021,2 genes,Lopez-Moya-2021-Chitosan inhibits septin-media,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18117,PHI:11236,,no data found,,,,,,nox1,,,,,,PHI:11237,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,NADPH oxidase,,,,increased virulence (hypervirulence),,,yes,yes,,,,reduced,,no,caspofungin,caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,33570748,PubMed,10.1111/nph.17268,New Phytol. 2021 May;230(4):1578-1593,nick.talbot@tsl.ac.uk,The Δnox1 mutant showed increased resistance to chitosan and was only slightly affected by chitosan at very high doses.,F Lopez-Moya 2021,2021,2 genes,Lopez-Moya-2021-Chitosan inhibits septin-media,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18118,PHI:11237,,no data found,,,,,,nox2,,,,,,PHI:11236,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,NADPH oxidase,,,,increased virulence (hypervirulence),,,yes,yes,,,,reduced,,no,caspofungin,caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,33570748,PubMed,10.1111/nph.17268,New Phytol. 2021 May;230(4):1578-1593,nick.talbot@tsl.ac.uk,The Δnox1 mutant showed increased resistance to chitosan and was only slightly affected by chitosan at very high doses.,F Lopez-Moya 2021,2021,2 genes,Lopez-Moya-2021-Chitosan inhibits septin-media,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18119,PHI:11238,UniProt,Q87NY3,GenBank,BAC59998,,,O3:K6,qseC,chromosome 1,,,,,,670,Vibrio parahaemolyticus,,VpAHPND 123,vibriosis,crustaceans,6661,Artemia franciscana (no common name found),San Francisco Bay Brand ASF65031,,,,putative two-component sensor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33553003,PubMed,10.3389/fcimb.2020.594652,Front Cell Infect Microbiol. 2021 Jan 21;10:594652,fusongzhe@hotmail.com,The ΔqseC mutant exhibited motility defects and marked reduction of biofilm formation compared with the parental strain.,Q Yang 2020,2020,1 gene,Yang-2020-QseC Inhibition as a Novel Antivirul,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18120,PHI:11239,UniProt,Q83Y51,GenBank,CAD70192,,,B301D-R,sylA,,,,,,,317,Pseudomonas syringae,205918,pv. syringae strain B728a,brown spot (bean),eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,"syringolin A, putative HTH_LUXR domain-containing transcription activator",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,18401409,PubMed,10.1038/nature06782,Nature. 2008 Apr 10;452(7188):755-8,rdudler@botinst.uzh.ch,Syringolin-negative mutant exhibited reduced virulence.,M Groll 2008,2008,1 gene,Groll-2008-A plant pathogen virulence factor i,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18121,PHI:11240,UniProt,Q9UVT8,GenBank,EHA58265,,,70-15,MoMca1 (MGG_04626),chromosome 3,,,,,,318829,Magnaporthe oryzae,,KV1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. YT16,,,leaf,"6,7-dimethyl-8-ribityllumazine synthase",,,,reduced virulence,,yes,,,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563831,PubMed,10.1128/mBio.03471-20,mBio. 2021 Feb 9;12(1):e03471-20,kim.orth@utsouthwestern.edu,"Deletion of both MoMca1 and MoMca2 in M. oryzae resulted in reduced sporulation, delay in conidial germination, and attenuation of disease severity.",J Fernandez 2021,2021,2 genes,Fernandez-2021-Role of Two Metacaspases in Dev,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18122,PHI:11241,UniProt,G4N7P4,GenBank,EHA50049,,,70-15,MoMca2 (MGG_13530),chromosome 4,,,,,,318829,Magnaporthe oryzae,,KV1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. YT16,,,leaf,metacaspase-1,,,,reduced virulence,,yes,,,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563831,PubMed,10.1128/mBio.03471-20,mBio. 2021 Feb 9;12(1):e03471-20,kim.orth@utsouthwestern.edu,"Deletion of both MoMca1 and MoMca2 in M. oryzae resulted in reduced sporulation, delay in conidial germination, and attenuation of disease severity.",J Fernandez 2021,2021,2 genes,Fernandez-2021-Role of Two Metacaspases in Dev,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18123,PHI:11240,UniProt,Q9UVT8,GenBank,EHA58265,,,70-15,MoMca1 (MGG_04626),chromosome 3,,,,,PHI:11241,318829,Magnaporthe oryzae,,KV1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. YT16,,,leaf,"6,7-dimethyl-8-ribityllumazine synthase",,,,reduced virulence,,yes,,,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563831,PubMed,10.1128/mBio.03471-20,mBio. 2021 Feb 9;12(1):e03471-20,kim.orth@utsouthwestern.edu,"Deletion of both MoMca1 and MoMca2 in M. oryzae resulted in reduced sporulation, delay in conidial germination, and attenuation of disease severity.",J Fernandez 2021,2021,2 genes,Fernandez-2021-Role of Two Metacaspases in Dev,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18124,PHI:11241,UniProt,G4N7P4,GenBank,EHA50049,,,70-15,MoMca2 (MGG_13530),chromosome 4,,,,,PHI:11240,318829,Magnaporthe oryzae,,KV1,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. YT16,,,leaf,metacaspase-1,,,,reduced virulence,,yes,,,,reduced,,,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563831,PubMed,10.1128/mBio.03471-20,mBio. 2021 Feb 9;12(1):e03471-20,kim.orth@utsouthwestern.edu,"Deletion of both MoMca1 and MoMca2 in M. oryzae resulted in reduced sporulation, delay in conidial germination, and attenuation of disease severity.",J Fernandez 2021,2021,2 genes,Fernandez-2021-Role of Two Metacaspases in Dev,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18125,PHI:11242,UniProt,Q5ZT21,GenBank,AAU28406,,,Philadelphia 1,mavE (lpg2344),,,,,,,446,Legionella pneumophila,,AA100/130b,Legionnaires' disease,primates,9606,Homo sapiens (related: human),,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563829,PubMed,10.1128/mBio.03458-20,mBio. 2021 Feb 9;12(1):e03458-20,abukwaik@louisville.edu,MavE effector was essential for intracellular growth of L. pneumophila in human monocyte-derived macrophages (hMDMs) and amoebae and for intrapulmonary proliferation in mice.,B Vaughn 2021,2021,1 gene,Vaughn-2021-An Indispensable Role for the MavE,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18126,PHI:11242,UniProt,Q5ZT21,GenBank,AAU28406,,,Philadelphia 1,mavE (lpg2344),,,,,,,446,Legionella pneumophila,,AA100/130b,Legionnaires' disease,eukaryotes,5757,Acanthamoeba polyphaga (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563829,PubMed,10.1128/mBio.03458-20,mBio. 2021 Feb 9;12(1):e03458-20,abukwaik@louisville.edu,MavE effector was essential for intracellular growth of L. pneumophila in human monocyte-derived macrophages (hMDMs) and amoebae and for intrapulmonary proliferation in mice.,B Vaughn 2021,2021,1 gene,Vaughn-2021-An Indispensable Role for the MavE,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18127,PHI:11242,UniProt,Q5ZT21,GenBank,AAU28406,,,Philadelphia 1,mavE (lpg2344),,,,,,,446,Legionella pneumophila,,AA100/130b,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung; liver; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563829,PubMed,10.1128/mBio.03458-20,mBio. 2021 Feb 9;12(1):e03458-20,abukwaik@louisville.edu,MavE effector was essential for intracellular growth of L. pneumophila in human monocyte-derived macrophages (hMDMs) and amoebae and for intrapulmonary proliferation in mice.,B Vaughn 2021,2021,1 gene,Vaughn-2021-An Indispensable Role for the MavE,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18128,PHI:11242,UniProt,Q5ZT21,GenBank,AAU28406,,,Philadelphia 1,mavE (lpg2344),,P78A and D64A,,,,,446,Legionella pneumophila,,AA100/130b,Legionnaires' disease,primates,9606,Homo sapiens (related: human),,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33563829,PubMed,10.1128/mBio.03458-20,mBio. 2021 Feb 9;12(1):e03458-20,abukwaik@louisville.edu,Two point mutations within the NPxY motif resulted in attenuation of L. pneumophila in both hMDMs and amoeba.,B Vaughn 2021,2021,1 gene,Vaughn-2021-An Indispensable Role for the MavE,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18129,PHI:11242,UniProt,Q5ZT21,GenBank,AAU28406,,,Philadelphia 1,mavE (lpg2344),,P78A and D64A,,,,,446,Legionella pneumophila,,AA100/130b,Legionnaires' disease,eukaryotes,5757,Acanthamoeba polyphaga (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33563829,PubMed,10.1128/mBio.03458-20,mBio. 2021 Feb 9;12(1):e03458-20,abukwaik@louisville.edu,Two point mutations within the NPxY motif resulted in attenuation of L. pneumophila in both hMDMs and amoeba.,B Vaughn 2021,2021,1 gene,Vaughn-2021-An Indispensable Role for the MavE,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18130,PHI:11243,UniProt,G4MZL0,GenBank,EHA54569,,,70-15,Mobre2 (MGG_01427),chromosome 2,,,MoSdc1 (MGG_00350),UniProt: G4NCQ5; GenBank: EHA49149,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,SET1 complex component,,,,reduced virulence,,,,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33559339,PubMed,10.1111/mpp.13035,Mol Plant Pathol. 2021 Apr;22(4):422-439,wangweixiang@bua.edu.cn,"MoBre2, MoSwd2, or MoSpp1 were critical for fungal development and invasive hyphae formation during pathogenesis",S Zhou 2021,2021,3 genes,Zhou-2021-The COMPASS-like complex modulates f,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18131,PHI:11244,UniProt,G5EI22,GenBank,EHA45944,,,70-15,Mospp1 (MGG_03005),chromosome 7,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,PHD-type domain-containing protein,,,,reduced virulence,,,,yes,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33559339,PubMed,10.1111/mpp.13035,Mol Plant Pathol. 2021 Apr;22(4):422-439,wangweixiang@bua.edu.cn,"MoBre2, MoSwd2, or MoSpp1 were critical for fungal development and invasive hyphae formation during pathogenesis",S Zhou 2021,2021,3 genes,Zhou-2021-The COMPASS-like complex modulates f,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18132,PHI:11245,UniProt,G4N7I7,GenBank,EHA50844,,,70-15,Moswd2 (MGG_06406),chromosome 4,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,WD_REPEATS_REGION domain-containing protein,,,,reduced virulence,,,,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33559339,PubMed,10.1111/mpp.13035,Mol Plant Pathol. 2021 Apr;22(4):422-439,wangweixiang@bua.edu.cn,"MoBre2, MoSwd2, or MoSpp1 were critical for fungal development and invasive hyphae formation during pathogenesis",S Zhou 2021,2021,3 genes,Zhou-2021-The COMPASS-like complex modulates f,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18133,PHI:11243,UniProt,G4MZL0,GenBank,EHA54569,,,70-15,Mobre2 (MGG_01427),chromosome 2,,,MoSdc1 (MGG_00350),UniProt: G4NCQ5; GenBank: EHA49149,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,SET1 complex component,,,,reduced virulence,,,,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33559339,PubMed,10.1111/mpp.13035,Mol Plant Pathol. 2021 Apr;22(4):422-439,wangweixiang@bua.edu.cn,"MoBre2, MoSwd2, or MoSpp1 were critical for fungal development and invasive hyphae formation during pathogenesis",S Zhou 2021,2021,3 genes,Zhou-2021-The COMPASS-like complex modulates f,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18134,PHI:11244,UniProt,G5EI22,GenBank,EHA45944,,,70-15,Mospp1 (MGG_03005),chromosome 7,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,PHD-type domain-containing protein,,,,reduced virulence,,,,yes,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33559339,PubMed,10.1111/mpp.13035,Mol Plant Pathol. 2021 Apr;22(4):422-439,wangweixiang@bua.edu.cn,"MoBre2, MoSwd2, or MoSpp1 were critical for fungal development and invasive hyphae formation during pathogenesis",S Zhou 2021,2021,3 genes,Zhou-2021-The COMPASS-like complex modulates f,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18135,PHI:11245,UniProt,G4N7I7,GenBank,EHA50844,,,70-15,Moswd2 (MGG_06406),chromosome 4,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,WD_REPEATS_REGION domain-containing protein,,,,reduced virulence,,,,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33559339,PubMed,10.1111/mpp.13035,Mol Plant Pathol. 2021 Apr;22(4):422-439,wangweixiang@bua.edu.cn,"MoBre2, MoSwd2, or MoSpp1 were critical for fungal development and invasive hyphae formation during pathogenesis",S Zhou 2021,2021,3 genes,Zhou-2021-The COMPASS-like complex modulates f,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18136,PHI:11246,UniProt,Q9HZL1,GenBank,AE004724_11,,,PAO1,nqrF,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,NADH dehydrogenase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33534802,PubMed,10.1371/journal.pone.0244142,PLoS One. 2021 Feb 3;16(2):e0244142,barqub@rpi.edu,"Some mutants, including the strain without NQR (ΔnqrF) had increased biofilm formation, pyocyanin production, and killed more efficiently in both macrophage and mouse infection models.",T N Hreha 2021,2021,3 genes,Hreha-2021-The three NADH dehydrogenases of Ps,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18137,PHI:11247,UniProt,Q9I0J6,GenBank,AE004693_1,,,PAO1,nuoG,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,NADH dehydrogenase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33534802,PubMed,10.1371/journal.pone.0244142,PLoS One. 2021 Feb 3;16(2):e0244142,barqub@rpi.edu,"Some mutants, including the strain without NQR (ΔnqrF) had increased biofilm formation, pyocyanin production, and killed more efficiently in both macrophage and mouse infection models.",T N Hreha 2021,2021,3 genes,Hreha-2021-The three NADH dehydrogenases of Ps,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18138,PHI:11248,UniProt,A0A069PYL4,GenBank,CEI15921,,,MH19,ndh,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,NADH dehydrogenase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33534802,PubMed,10.1371/journal.pone.0244142,PLoS One. 2021 Feb 3;16(2):e0244142,barqub@rpi.edu,"Some mutants, including the strain without NQR (ΔnqrF) had increased biofilm formation, pyocyanin production, and killed more efficiently in both macrophage and mouse infection models.",T N Hreha 2021,2021,3 genes,Hreha-2021-The three NADH dehydrogenases of Ps,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18139,PHI:11246,UniProt,Q9HZL1,GenBank,AE004724_11,,,PAO1,nqrF,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,NADH dehydrogenase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33534802,PubMed,10.1371/journal.pone.0244142,PLoS One. 2021 Feb 3;16(2):e0244142,barqub@rpi.edu,"Some mutants, including the strain without NQR (ΔnqrF) had increased biofilm formation, pyocyanin production, and killed more efficiently in both macrophage and mouse infection models.",T N Hreha 2021,2021,3 genes,Hreha-2021-The three NADH dehydrogenases of Ps,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18140,PHI:11249,UniProt,N4X8R0,GenBank,ENI09439,,,ATCC 48331,cdc14,,,,,,,5016,Bipolaris maydis,,,southern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,leaf,dual-specificity phosphatase,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33530602,PubMed,10.3390/jof7020083,J Fungi (Basel). 2021 Jan 26;7(2):83,ronik@technion.ac.il,"The loss of the dual-specificity phosphatase CDC14 led to slow growth, decreased virulence, and attenuated dephosphorylation.",R Zuchman 2021,2021,4 genes,Zuchman-2021-Developmental Roles of the Hog1 P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18141,PHI:11250,UniProt,N4X174,GenBank,ENI05460,,,ATCC 48331,ptcB,,,,,,,5016,Bipolaris maydis,,,southern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33530602,PubMed,10.3390/jof7020083,J Fungi (Basel). 2021 Jan 26;7(2):83,ronik@technion.ac.il,"The loss of the dual-specificity phosphatase CDC14 led to slow growth, decreased virulence, and attenuated dephosphorylation.",R Zuchman 2021,2021,4 genes,Zuchman-2021-Developmental Roles of the Hog1 P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18142,PHI:11251,,no data found,,,,,,PTP1,,,,,,,5016,Bipolaris maydis,,,southern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,leaf,tyrosine phosphatase,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33530602,PubMed,10.3390/jof7020083,J Fungi (Basel). 2021 Jan 26;7(2):83,ronik@technion.ac.il,Mutants in two predicted tyrosine phosphatase genes PTP1 and PTP2 showed normal development and virulence.,R Zuchman 2021,2021,4 genes,Zuchman-2021-Developmental Roles of the Hog1 P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18143,PHI:11252,,no data found,,,,,,PTP2,,,,,,,5016,Bipolaris maydis,,,southern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,leaf,tyrosine phosphatase,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33530602,PubMed,10.3390/jof7020083,J Fungi (Basel). 2021 Jan 26;7(2):83,ronik@technion.ac.il,Mutants in two predicted tyrosine phosphatase genes PTP1 and PTP2 showed normal development and virulence.,R Zuchman 2021,2021,4 genes,Zuchman-2021-Developmental Roles of the Hog1 P,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18144,PHI:11253,,no data found,,,,,,xrrA,,,,,,,1392,Bacillus anthracis,,ANR-1,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen; kidney,small regulatory RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33519762,PubMed,10.3389/fmicb.2020.610036,Front Microbiol. 2021 Jan 15;11:610036,Theresa.M.Koehler@uth.tmc.edu,"In a mouse model for systemic anthrax, the lungs and livers of animals infected with xrrA-null mutants had a small reduction in bacterial burden.",I D Corsi 2020,2020,2 genes,Corsi-2020-AtxA-Controlled Small RNAs of Bacil,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18145,PHI:11253,,no data found,,,,,,xrrA,,,,,,PHI:11254,1392,Bacillus anthracis,,ANR-1,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen; kidney; liver,small regulatory RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33519762,PubMed,10.3389/fmicb.2020.610036,Front Microbiol. 2021 Jan 15;11:610036,Theresa.M.Koehler@uth.tmc.edu,"In a mouse model for systemic anthrax, the lungs and livers of animals infected with xrrA-null mutants had a small reduction in bacterial burden.",I D Corsi 2020,2020,2 genes,Corsi-2020-AtxA-Controlled Small RNAs of Bacil,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18146,PHI:11254,,no data found,,,,,,xrrB,,,,,,PHI:11253,1392,Bacillus anthracis,,ANR-1,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,spleen; kidney; liver,small regulatory RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33519762,PubMed,10.3389/fmicb.2020.610036,Front Microbiol. 2021 Jan 15;11:610036,Theresa.M.Koehler@uth.tmc.edu,"In a mouse model for systemic anthrax, the lungs and livers of animals infected with xrrA-null mutants had a small reduction in bacterial burden.",I D Corsi 2020,2020,2 genes,Corsi-2020-AtxA-Controlled Small RNAs of Bacil,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18147,PHI:11253,,no data found,,,,,,xrrA,,,,,,,1392,Bacillus anthracis,,ANR-1,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,liver; lung,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33519762,PubMed,10.3389/fmicb.2020.610036,Front Microbiol. 2021 Jan 15;11:610036,Theresa.M.Koehler@uth.tmc.edu,"In a mouse model for systemic anthrax, the lungs and livers of animals infected with xrrA-null mutants had a small reduction in bacterial burden.",I D Corsi 2020,2020,2 genes,Corsi-2020-AtxA-Controlled Small RNAs of Bacil,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18148,PHI:11253,,no data found,,,,,,xrrA,,,,,,PHI:11254,1392,Bacillus anthracis,,ANR-1,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33519762,PubMed,10.3389/fmicb.2020.610036,Front Microbiol. 2021 Jan 15;11:610036,Theresa.M.Koehler@uth.tmc.edu,"In a mouse model for systemic anthrax, the lungs and livers of animals infected with xrrA-null mutants had a small reduction in bacterial burden.",I D Corsi 2020,2020,2 genes,Corsi-2020-AtxA-Controlled Small RNAs of Bacil,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18149,PHI:11254,,no data found,,,,,,xrrB,,,,,,PHI:11253,1392,Bacillus anthracis,,ANR-1,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33519762,PubMed,10.3389/fmicb.2020.610036,Front Microbiol. 2021 Jan 15;11:610036,Theresa.M.Koehler@uth.tmc.edu,"In a mouse model for systemic anthrax, the lungs and livers of animals infected with xrrA-null mutants had a small reduction in bacterial burden.",I D Corsi 2020,2020,2 genes,Corsi-2020-AtxA-Controlled Small RNAs of Bacil,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18150,PHI:11255,UniProt,A0A2X2YC17,GenBank,SQB60503,,,NCTC10719,fimA,,,,,,,1502,Clostridium perfringens,,CP1,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 708,,,,type IV pilin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33468589,PubMed,10.1128/JB.00578-20,J Bacteriol. 2021 Mar 8;203(7):e00578-20,joshua.gong@canada.ca,The fimA and fimB null mutants were both severely attenuated in their ability to cause disease in an in vivo chicken NE challenge model.,D Lepp 2021,2021,2 genes,Lepp-2021-Clostridium perfringens Produces an,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18151,PHI:11256,,no data found,,,,,,fimB,,,,,,,1502,Clostridium perfringens,,CP1,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 708,,,,pilin subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33468589,PubMed,10.1128/JB.00578-20,J Bacteriol. 2021 Mar 8;203(7):e00578-20,joshua.gong@canada.ca,The fimA and fimB null mutants were both severely attenuated in their ability to cause disease in an in vivo chicken NE challenge model.,D Lepp 2021,2021,2 genes,Lepp-2021-Clostridium perfringens Produces an,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18152,PHI:11257,UniProt,A0A2H3U592,GenBank,SCO92080,,,V64-1,FoMep1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker Cf-0,,,seedling,probable metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25915453,PubMed,10.1094/MPMI-04-15-0074-R,Mol Plant Microbe Interact. 2015 Sep;28(9):996-1008,Pierre.deWit@wur.nl,Double deletion mutants of FoMep1 and FoSep1 of F. oxysporum lacked chitinase cleavage activity on SlChi1 and SlChi13 and showed reduced virulence on tomato.,M K Jashni 2015,2015,2 genes,mpmi-04-15-0074-r,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18153,PHI:11258,UniProt,A0A559LXH4,GenBank,TVY80081,,,160527,FoSep1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker Cf-0,,,seedling,forkhead protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25915453,PubMed,10.1094/MPMI-04-15-0074-R,Mol Plant Microbe Interact. 2015 Sep;28(9):996-1008,Pierre.deWit@wur.nl,Double deletion mutants of FoMep1 and FoSep1 of F. oxysporum lacked chitinase cleavage activity on SlChi1 and SlChi13 and showed reduced virulence on tomato.,M K Jashni 2015,2015,2 genes,mpmi-04-15-0074-r,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18154,PHI:11257,UniProt,A0A2H3U592,GenBank,SCO92080,,,V64-1,FoMep1,,,,,,PHI:11258,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker Cf-0,,,seedling,probable metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25915453,PubMed,10.1094/MPMI-04-15-0074-R,Mol Plant Microbe Interact. 2015 Sep;28(9):996-1008,Pierre.deWit@wur.nl,Double deletion mutants of FoMep1 and FoSep1 of F. oxysporum lacked chitinase cleavage activity on SlChi1 and SlChi13 and showed reduced virulence on tomato.,M K Jashni 2015,2015,2 genes,mpmi-04-15-0074-r,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18155,PHI:11258,UniProt,A0A559LXH4,GenBank,TVY80081,,,160527,FoSep1,,,,,,PHI:11257,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker Cf-0,,,seedling,forkhead protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,25915453,PubMed,10.1094/MPMI-04-15-0074-R,Mol Plant Microbe Interact. 2015 Sep;28(9):996-1008,Pierre.deWit@wur.nl,Double deletion mutants of FoMep1 and FoSep1 of F. oxysporum lacked chitinase cleavage activity on SlChi1 and SlChi13 and showed reduced virulence on tomato.,M K Jashni 2015,2015,2 genes,mpmi-04-15-0074-r,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18156,PHI:11259,UniProt,P08191,GenBank,AAC77276,,,K-12,fimH,,,,,,,562,Escherichia coli,364106,UTI89,pyelonephritis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,urinary bladder; kidney,type 1 fimbrin D-mannose specific adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33513212,PubMed,10.1371/journal.ppat.1009314,PLoS Pathog. 2021 Jan 29;17(1):e1009314,dhunstad@wustl.edu,Bacterial mutants lacking the type 1 pilus adhesin (FimH) were unable to establish kidney infection in male C3H/HeN mice.,L K McLellan 2021,2021,1 gene,McLellan-2021-A host receptor enables type 1 p,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18157,PHI:11260,UniProt,B3FRA4,GenBank,ACA62938,,,RH,tgif2k-b,,,,,,,5811,Toxoplasma gondii,508771,type II strain ME49,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,initiation factor-2 alpha kinase-B,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33500345,PubMed,10.1128/mBio.03160-20,mBio. 2021 Jan 26;12(1):e03160-20,wjsulliv@iu.edu,Parasites lacking TgIF2K-B exhibited resistance to activated macrophages and showed greater virulence in an in vivo model of infection.,L Augusto 2021,2021,1 gene,Augusto-2021-TgIF2K-B Is an eIF2α Kinase in To,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18158,PHI:11260,UniProt,B3FRA4,GenBank,ACA62938,,,RH,tgif2k-b,,,,,,,5811,Toxoplasma gondii,508771,type II strain ME49,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,initiation factor-2 alpha kinase-B,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33500345,PubMed,10.1128/mBio.03160-20,mBio. 2021 Jan 26;12(1):e03160-20,wjsulliv@iu.edu,Parasites lacking TgIF2K-B exhibited resistance to activated macrophages and showed greater virulence in an in vivo model of infection.,L Augusto 2021,2021,1 gene,Augusto-2021-TgIF2K-B Is an eIF2α Kinase in To,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18159,PHI:11261,UniProt,A0A0D5YNH1,GenBank,AKA33448,,,AB5075-UW,abaM (ABUW_3775),,abaM::T26,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DUF4902 domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33495249,PubMed,10.1128/JB.00635-20,J Bacteriol. 2021 Mar 23;203(8):e00635-20,paul.williams@nottingham.ac.uk,"In contrast to the wild type and the abaI::T26 mutant, the virulence of the abaM::T26 mutant was completely attenuated in a Galleria mellonella infection model.",M López-Martín 2021,2021,2 genes,López-Martín-2021-AbaM Regulates Quorum Sensin,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18160,PHI:11262,UniProt,B0FLN1,GenBank,ABY50954,,,M2,abaI,,abaI::T26,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,acyl-homoserine-lactone synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33495249,PubMed,10.1128/JB.00635-20,J Bacteriol. 2021 Mar 23;203(8):e00635-20,paul.williams@nottingham.ac.uk,"In contrast to the wild type and the abaI::T26 mutant, the virulence of the abaM::T26 mutant was completely attenuated in a Galleria mellonella infection model.",M López-Martín 2021,2021,2 genes,López-Martín-2021-AbaM Regulates Quorum Sensin,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18161,PHI:11263,UniProt,A5ICA4,GenBank,ABQ55004,,,Corby,proA,,,,,,,446,Legionella pneumophila,400673,Corby,Legionnaires' disease,primates,9606,Homo sapiens (related: human),,,,lung,gamma-glutamyl phosphate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33491325,PubMed,10.1111/cmi.13313,Cell Microbiol. 2021 May;23(5):e13313,m.steinert@tu-bs.de,The moderate attenuation of a proAnegative mutant in A549 epithelial cells and THP-1 macrophages suggests that effectsof ProA in tissue mainly result from extracellular activity.,L Scheithauer 2021,2021,1 gene,Scheithauer-2021-Zinc metalloprotease ProA of,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18162,PHI:11263,UniProt,A5ICA4,GenBank,ABQ55004,,,Corby,proA,,,,,,,446,Legionella pneumophila,400673,Corby,Legionnaires' disease,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,gamma-glutamyl phosphate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33491325,PubMed,10.1111/cmi.13313,Cell Microbiol. 2021 May;23(5):e13313,m.steinert@tu-bs.de,The moderate attenuation of a proAnegative mutant in A549 epithelial cells and THP-1 macrophages suggests that effectsof ProA in tissue mainly result from extracellular activity.,L Scheithauer 2021,2021,1 gene,Scheithauer-2021-Zinc metalloprotease ProA of,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18163,PHI:11263,UniProt,A5ICA4,GenBank,ABQ55004,,,Corby,proA,,,,,,,446,Legionella pneumophila,400673,Corby,Legionnaires' disease,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,monocyte,gamma-glutamyl phosphate reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33491325,PubMed,10.1111/cmi.13313,Cell Microbiol. 2021 May;23(5):e13313,m.steinert@tu-bs.de,The moderate attenuation of a proAnegative mutant in A549 epithelial cells and THP-1 macrophages suggests that effectsof ProA in tissue mainly result from extracellular activity.,L Scheithauer 2021,2021,1 gene,Scheithauer-2021-Zinc metalloprotease ProA of,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18164,PHI:11264,UniProt,A0A411PX52,GenBank,QBG49687,,,BpShHep31,pirB,,,,,,,670,Vibrio parahaemolyticus,,,vibriosis,crustaceans,6689,Penaeus vannamei (related: Pacific white shrimp),,,,hemocyte,toxin protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,33487106,PubMed,10.1080/21505594.2021.1872171,Virulence. 2021 Dec;12(1):481-492,zhangyl@stu.edu.cn,"The PirB toxin protein interacted with histones to affect the phosphorylation of histone H3-S10, thereby inducing apoptosis.",Z Zheng 2021,2021,1 gene,Zheng-2021-The PirB toxin protein from Vibrio,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18165,PHI:11265,UniProt,P12681,GenBank,AAL21299,,,LT2,pgtP,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,phosphoglycerate transporter protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563986,PubMed,10.1038/s41467-021-21186-4,Nat Commun. 2021 Feb 9;12(1):879,wanglei@nankai.edu.cn,"STM reprograms the macrophage metabolism by using a T3SS effector to repress the host serine synthesis pathway by repressing the key enzyme Phgdh, which could represent a promising target to control STM systemic infection.",L Jiang 2021,2021,4 genes,Jiang-2021-Salmonella Typhimurium reprograms m,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18166,PHI:11266,UniProt,Q8ZMQ6,GenBank,AAL21634,,,LT2,vrpA (STM2748),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,putative transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563986,PubMed,10.1038/s41467-021-21186-4,Nat Commun. 2021 Feb 9;12(1):879,wanglei@nankai.edu.cn,"STM reprograms the macrophage metabolism by using a T3SS effector to repress the host serine synthesis pathway by repressing the key enzyme Phgdh, which could represent a promising target to control STM systemic infection.",L Jiang 2021,2021,4 genes,Jiang-2021-Salmonella Typhimurium reprograms m,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18167,PHI:11265,UniProt,P12681,GenBank,AAL21299,,,LT2,pgtP,,,,,,PHI:11266,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,phosphoglycerate transporter protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563986,PubMed,10.1038/s41467-021-21186-4,Nat Commun. 2021 Feb 9;12(1):879,wanglei@nankai.edu.cn,"STM reprograms the macrophage metabolism by using a T3SS effector to repress the host serine synthesis pathway by repressing the key enzyme Phgdh, which could represent a promising target to control STM systemic infection.",L Jiang 2021,2021,4 genes,Jiang-2021-Salmonella Typhimurium reprograms m,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18168,PHI:11266,UniProt,Q8ZMQ6,GenBank,AAL21634,,,LT2,vrpA (STM2748),,,,,,PHI:11265,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,putative transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563986,PubMed,10.1038/s41467-021-21186-4,Nat Commun. 2021 Feb 9;12(1):879,wanglei@nankai.edu.cn,"STM reprograms the macrophage metabolism by using a T3SS effector to repress the host serine synthesis pathway by repressing the key enzyme Phgdh, which could represent a promising target to control STM systemic infection.",L Jiang 2021,2021,4 genes,Jiang-2021-Salmonella Typhimurium reprograms m,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18169,PHI:11267,UniProt,Q7CQ82,GenBank,AAL21084,,,LT2,vrpB (STM2180),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,putative LysR family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563986,PubMed,10.1038/s41467-021-21186-4,Nat Commun. 2021 Feb 9;12(1):879,wanglei@nankai.edu.cn,"STM reprograms the macrophage metabolism by using a T3SS effector to repress the host serine synthesis pathway by repressing the key enzyme Phgdh, which could represent a promising target to control STM systemic infection.",L Jiang 2021,2021,4 genes,Jiang-2021-Salmonella Typhimurium reprograms m,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18170,PHI:11268,UniProt,Q8ZJU6,GenBank,AAL23403,,,LT2,creB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,response regulator in two-component regulatory system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563986,PubMed,10.1038/s41467-021-21186-4,Nat Commun. 2021 Feb 9;12(1):879,wanglei@nankai.edu.cn,"STM reprograms the macrophage metabolism by using a T3SS effector to repress the host serine synthesis pathway by repressing the key enzyme Phgdh, which could represent a promising target to control STM systemic infection.",L Jiang 2021,2021,4 genes,Jiang-2021-Salmonella Typhimurium reprograms m,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18171,PHI:11267,UniProt,Q7CQ82,GenBank,AAL21084,,,LT2,vrpB (STM2180),,,,,,PHI:11268,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,putative LysR family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563986,PubMed,10.1038/s41467-021-21186-4,Nat Commun. 2021 Feb 9;12(1):879,wanglei@nankai.edu.cn,"STM reprograms the macrophage metabolism by using a T3SS effector to repress the host serine synthesis pathway by repressing the key enzyme Phgdh, which could represent a promising target to control STM systemic infection.",L Jiang 2021,2021,4 genes,Jiang-2021-Salmonella Typhimurium reprograms m,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18172,PHI:11268,UniProt,Q8ZJU6,GenBank,AAL23403,,,LT2,creB,,,,,,PHI:11267,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,response regulator in two-component regulatory system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33563986,PubMed,10.1038/s41467-021-21186-4,Nat Commun. 2021 Feb 9;12(1):879,wanglei@nankai.edu.cn,"STM reprograms the macrophage metabolism by using a T3SS effector to repress the host serine synthesis pathway by repressing the key enzyme Phgdh, which could represent a promising target to control STM systemic infection.",L Jiang 2021,2021,4 genes,Jiang-2021-Salmonella Typhimurium reprograms m,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18173,PHI:11269,UniProt,P99143,GenBank,BAB42180,,,N315,ptsH,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,kidney; liver,histidine-containing phosphocarrier protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33668335,PubMed,10.3390/microorganisms9030466,Microorganisms. 2021 Feb 24;9(3):466,markus.bischoff@uks.eu,Inactivation of ptsH and/or ccpA results in decreased bacterial burden of S. aureus Newman in a murine abscess model.,L Pätzold 2021,2021,2 genes,Pätzold-2021-Impact of the Histidine-Containin,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18174,PHI:11270,UniProt,P99175,GenBank,BAB42825,,,N315,ccpA,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,kidney; liver,catabolite control protein A,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33668335,PubMed,10.3390/microorganisms9030466,Microorganisms. 2021 Feb 24;9(3):466,markus.bischoff@uks.eu,Inactivation of ptsH and/or ccpA results in decreased bacterial burden of S. aureus Newman in a murine abscess model.,L Pätzold 2021,2021,2 genes,Pätzold-2021-Impact of the Histidine-Containin,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18175,PHI:11269,UniProt,P99143,GenBank,BAB42180,,,N315,ptsH,,,,,,PHI:11270,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,kidney; liver,histidine-containing phosphocarrier protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33668335,PubMed,10.3390/microorganisms9030466,Microorganisms. 2021 Feb 24;9(3):466,markus.bischoff@uks.eu,Inactivation of ptsH and/or ccpA results in decreased bacterial burden of S. aureus Newman in a murine abscess model.,L Pätzold 2021,2021,2 genes,Pätzold-2021-Impact of the Histidine-Containin,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18176,PHI:11270,UniProt,P99175,GenBank,BAB42825,,,N315,ccpA,,,,,,PHI:11269,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,kidney; liver,catabolite control protein A,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33668335,PubMed,10.3390/microorganisms9030466,Microorganisms. 2021 Feb 24;9(3):466,markus.bischoff@uks.eu,Inactivation of ptsH and/or ccpA results in decreased bacterial burden of S. aureus Newman in a murine abscess model.,L Pätzold 2021,2021,2 genes,Pätzold-2021-Impact of the Histidine-Containin,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18177,PHI:11269,UniProt,P99143,GenBank,BAB42180,,,N315,ptsH,,,,,,,1280,Staphylococcus aureus,,SA113,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6N,,,kidney; liver,histidine-containing phosphocarrier protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33668335,PubMed,10.3390/microorganisms9030466,Microorganisms. 2021 Feb 24;9(3):466,markus.bischoff@uks.eu,Inactivation of ptsH and/or ccpA results in decreased bacterial burden of S. aureus Newman in a murine abscess model.,L Pätzold 2021,2021,2 genes,Pätzold-2021-Impact of the Histidine-Containin,BATCH_105B,2021-04-01,MC,,,,,,,,,,,,,
,,Record 18178,PHI:7050,UniProt,I6L8Z5,GenBank,AE014984_3,,,UA159,covR,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,blood,orphan response regulator,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18179,PHI:7051,UniProt,Q8DTF1,GenBank,AE014973_2,,,UA159,gbpC,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,blood,glucan-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18180,PHI:7052,UniProt,Q8DTB7,GenBank,AE014976_8,,,UA159,epsC,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,blood,exopolysaccharide synthesis enzyme [UDP-N-acetylglucosamine 2-epimerase],,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18181,PHI:7053,UniProt,P08987,GenBank,AE014940_1,,,UA159,gtfB,,,,,,PHI:7054; PHI:7055,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,blood,glucosyltransferase,,,glucan synthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18182,PHI:7054,UniProt,P13470,GenBank,AE014940_2,,,UA159,gtfC,,,,,,PHI:7053; PHI:7055,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,blood,glucosyltransferase,,,glucan synthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18183,PHI:7055,UniProt,P49331,GenBank,AE014932_2,,,UA159,gtfD,,,,,,PHI:7053; PHI:7054,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,blood,glucosyltransferase,,,glucan synthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18184,PHI:7050,UniProt,I6L8Z5,GenBank,AE014984_3,,,UA159,covR,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,primates,9606,Homo sapiens (related: human),,,,blood,orphan response regulator,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18185,PHI:7051,UniProt,Q8DTF1,GenBank,AE014973_2,,,UA159,gbpC,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,primates,9606,Homo sapiens (related: human),,,,blood,glucan-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18186,PHI:7052,UniProt,Q8DTB7,GenBank,AE014976_8,,,UA159,epsC,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,primates,9606,Homo sapiens (related: human),,,,blood,exopolysaccharide synthesis enzyme [UDP-N-acetylglucosamine 2-epimerase],,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18187,PHI:7053,UniProt,P08987,GenBank,AE014940_1,,,UA159,gtfB,,,,,,PHI:7054; PHI:7055,1309,Streptococcus mutans,210007,UA159,infective endocarditis,primates,9606,Homo sapiens (related: human),,,,blood,glucosyltransferase,,,glucan synthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18188,PHI:7054,UniProt,P13470,GenBank,AE014940_2,,,UA159,gtfC,,,,,,PHI:7053; PHI:7055,1309,Streptococcus mutans,210007,UA159,infective endocarditis,primates,9606,Homo sapiens (related: human),,,,blood,glucosyltransferase,,,glucan synthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18189,PHI:7055,UniProt,P49331,GenBank,AE014932_2,,,UA159,gtfD,,,,,,PHI:7053; PHI:7054,1309,Streptococcus mutans,210007,UA159,infective endocarditis,primates,9606,Homo sapiens (related: human),,,,blood,glucosyltransferase,,,glucan synthesis,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,27572331,PubMed,10.1128/IAI.00406-16,Infect Immun. 2016 Oct 17;84(11):3206-3219,rmgraner@fop.unicamp.br,"UAcov showed increased exvivo survival in human blood in an EPS dependent way. Consistently, reduced survival was observed for the gbpC and epsC mutants.",L A Alves 2016,2016,6 genes,Alves-2016-CovR regulates Streptococcus mutans,BATCH_067B,2017-05-01,MC,,,,,,,,,,,,,
,,Record 18190,PHI:8088,UniProt,Q8DUS1,GenBank,AE014924_6,,,UA159,rgpf (SMU.830),,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,rhamnosyltransferase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,28924033,PubMed,10.1128/JB.00497-17,J Bacteriol. 2017 Nov 14;199(24). pii: e00497-17,Robert_Quivey@urmc.rochester.edu,"The loss of rgpF caused a perturbation of membrane-associated functions known to be critical for aciduricity, a hallmark of S. mutans acid tolerance.",C J Kovacs 2017,2017,1 gene,Kovacs-2017-RgpF is required for maintenance o,BATCH_082,2018-05-01,MC,,,,,,,,,,,,,
,,Record 18191,PHI:9976,UniProt,no data found,GenBank,AFM51859,,,,Mbov_0503,,,,,,,28903,Mycoplasmopsis bovis,,HB0801,,even-toed ungulates,9913,Bos taurus (related: cattle),EBL cell line,,,lung,"cytoadhesin, transmembrane protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31979335,PubMed,10.3390/microorganisms8020164,Microorganisms. 2020 Jan 23;8(2),aizhen@mail.hzau.edu.cn,"Although Mbov_0503 disruption was only associated in M. bovis with a partial reduction of its binding capacity, this moderate eect was sucient to aect M. bovis interaction with the host-cell tight junctions, and reduce the translocation of this mycoplasma across epithelial cell monolayers.to",X Zhu 2020,2020,1 gene,Zhu-2020-Mbov_0503 Encodes a Novel Cytoadhesin,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 18192,PHI:9976,UniProt,no data found,GenBank,AFM51859,,,,Mbov_0503,,,,,,,28903,Mycoplasmopsis bovis,,HB0801,,even-toed ungulates,9913,Bos taurus (related: cattle),MDBK cell line,,,MDBK cell,"cytoadhesin, transmembrane protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31979335,PubMed,10.3390/microorganisms8020164,Microorganisms. 2020 Jan 23;8(2),aizhen@mail.hzau.edu.cn,"Although Mbov_0503 disruption was only associated in M. bovis with a partial reduction of its binding capacity, this moderate eect was sucient to aect M. bovis interaction with the host-cell tight junctions, and reduce the translocation of this mycoplasma across epithelial cell monolayers.to",X Zhu 2020,2020,1 gene,Zhu-2020-Mbov_0503 Encodes a Novel Cytoadhesin,BATCH_099B,2020-03-01,MC,,,,,,,,,,,,,
,,Record 18193,PHI:11271,UniProt,G4NGB5,GenBank,EHA47072,,,70-15,MoAfo1 (MGG_10422),chromosome 6,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: Rice),cv. Nakdongbyeo,,,leaf,membrane bound protein,,,,reduced virulence,,yes,yes,yes,,reduced,,wild type,wild type,no,"H2O2; 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonate)","H2O2: CHEBI:16240; 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonate): CAS:30931-67-0",,,,,gene deletion: full; gene complementation,,,YVS,33866752,PubMed,10.5423/PPJ.OA.08.2020.0154. Epub 2021 Apr 1,Plant Pathol J. 2021 Apr;37(2):87-98,jaehyukc@inu.ac.kr,"The ΔMoafo1 mutant showed defects in appressorium morphology, appressorium penetration, invasive growth, and pathogenicity.",M A Sadat 2021,2021,1 gene,"Sadat-2021-The Membrane-Bound Protein, MoAfo1",BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18194,PHI:11272,,no data found,,,,,,sprC,,,,,,,1280,Staphylococcus aureus,,HG003,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33954118,PubMed,10.3389/fcimb.2021.631710,Front Cell Infect Microbiol. 2021 Apr 19;11:631710,pierre-yves.donnio@univ-rennes1.fr,The decrease in death rates was delayed when either sprD or sprC was lacking.,G Ménard 2021,2021,4 genes,Ménard-2021-Galleria mellonella Larvae as an I,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18195,PHI:11273,,no data found,,,,,,sprD,,,,,,,1280,Staphylococcus aureus,,HG001,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33954118,PubMed,10.3389/fcimb.2021.631710,Front Cell Infect Microbiol. 2021 Apr 19;11:631710,pierre-yves.donnio@univ-rennes1.fr,The decrease in death rates was delayed when either sprD or sprC was lacking.,G Ménard 2021,2021,4 genes,Ménard-2021-Galleria mellonella Larvae as an I,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18196,PHI:11274,,no data found,,,,,,sprX,,,,,,,1280,Staphylococcus aureus,,HG001,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,small regulatory RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33954118,PubMed,10.3389/fcimb.2021.631710,Front Cell Infect Microbiol. 2021 Apr 19;11:631710,pierre-yves.donnio@univ-rennes1.fr,The decrease in death rates was delayed when either sprD or sprC was lacking.,G Ménard 2021,2021,4 genes,Ménard-2021-Galleria mellonella Larvae as an I,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18197,PHI:11275,,no data found,,,,,,rnaIII,,,,,,,1280,Staphylococcus aureus,,HG003,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,small regulatory RNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33954118,PubMed,10.3389/fcimb.2021.631710,Front Cell Infect Microbiol. 2021 Apr 19;11:631710,pierre-yves.donnio@univ-rennes1.fr,The decrease in death rates was delayed when either sprD or sprC was lacking.,G Ménard 2021,2021,4 genes,Ménard-2021-Galleria mellonella Larvae as an I,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18198,PHI:11276,UniProt,A0A346FLS9,GenBank,AXN69804,,,NRRL 38154,FgRbp1,,,,FgU2AF23,UniProt: A0A2H3FI17; GenBank: CZS72592,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,inflorescence,RNA binding protein,,,,reduced virulence,,yes,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33976182,PubMed,10.1038/s41467-021-22917-3,Nat Commun. 2021 May 11;12(1):2661,zhma@zju.edu.cn,The loss of pathogenicity was due to the defect in penetration capability in ΔFgRbp1.,M Wang 2021,2021,1 gene,Wang-2021-The RNA binding protein FgRbp1 regul,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18199,PHI:11276,UniProt,A0A346FLS9,GenBank,AXN69804,,,NRRL 38154,FgRbp1,,,,FgU2AF23,UniProt: A0A2H3FI17; GenBank: CZS72592,,5518,Fusarium graminearum,229533,PH-1,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,corn silk,RNA binding protein,,,,reduced virulence,,yes,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33976182,PubMed,10.1038/s41467-021-22917-3,Nat Commun. 2021 May 11;12(1):2661,zhma@zju.edu.cn,The loss of pathogenicity was due to the defect in penetration capability in ΔFgRbp1.,M Wang 2021,2021,1 gene,Wang-2021-The RNA binding protein FgRbp1 regul,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18200,PHI:11277,UniProt,Q1RPI4,GenBank,AIX63806,,,ECONIH1,ybtE,,,,,,,562,Escherichia coli,591946,LF82,infection,primates,9606,Homo sapiens (related: human),T84 cell line,,,intestinal epithelial cell,yersiniabactin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33805299,PubMed,10.3390/ijms22073512,Int J Mol Sci. 2021 Mar 29;22(7):3512,rbonnet@chu-clermontferrand.f,"Loss of yersiniabactin decreased the growth of LF82 in competitive conditions, reducing the ability of LF82 to adhere to and invade T84 cells and to colonize the intestinal tract of CEABAC10 mice.",G Dalmasso 2021,2021,1 gene,Dalmasso-2021-Yersiniabactin Siderophore of Cr,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18201,PHI:11277,UniProt,Q1RPI4,GenBank,AIX63806,,,ECONIH1,ybtE,,,,,,,562,Escherichia coli,591946,LF82,infection,rodents,10090,Mus musculus (related: house mouse),CEABAC10,,,ileal mucosa,yersiniabactin,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33805299,PubMed,10.3390/ijms22073512,Int J Mol Sci. 2021 Mar 29;22(7):3512,rbonnet@chu-clermontferrand.f,"Loss of yersiniabactin decreased the growth of LF82 in competitive conditions, reducing the ability of LF82 to adhere to and invade T84 cells and to colonize the intestinal tract of CEABAC10 mice.",G Dalmasso 2021,2021,1 gene,Dalmasso-2021-Yersiniabactin Siderophore of Cr,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18202,PHI:11278,UniProt,P62576,GenBank,AAL00340,,,R6,nanA,,,,,,,1313,Streptococcus pneumoniae,373153,D39,otitis media,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,sialidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33777832,PubMed,10.3389/fcimb.2021.613195. eCollection 2021,Front Cell Infect Microbiol. 2021 Mar 11;11:613195,yungchiychang@ntu.edu.tw,Targeting NanA activity may ameliorate the pneumococcus-mediated inflammation and cytotoxicity in severe invasive pneumococcal diseases.,Y W Tseng 2021,2021,1 gene,Tseng-2021-Novel Virulence Role of Pneumococca,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18203,PHI:11279,,no data found,GenBank,BAX74398,,,No.10,psmalpha,,,,,,PHI:11280,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,phenol soluble modulin alpha,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18204,PHI:11280,,no data found,GenBank,BAX75025,,,No.10,psmbeta,,,,,,PHI:11279,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,phenol soluble modulin beta,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18205,PHI:11281,UniProt,P0A0I7,GenBank,AGRA_STAAU,,,,agr,,,,,,,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,accessory gene regulator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18206,PHI:11279,,no data found,GenBank,BAX74398,,,No.10,psmalpha,,,,,,PHI:11280; PHI:11282; PHI:11283; PHI:11284,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,phenol soluble modulin alpha,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18207,PHI:11280,,no data found,GenBank,BAX75025,,,No.10,psmbeta,,,,,,PHI:11279; PHI:11282; PHI:11283; PHI:11284,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,phenol soluble modulin beta,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18208,PHI:11282,UniProt,W8TMV6,GenBank,AUS75139,,,MRSA107,relP,,,,,,PHI:11279; PHI:11280; PHI:11283; PHI:11284,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,(P)ppGpp synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18209,PHI:11283,,no data found,GenBank,OBY01590,,,137/93G,relQ,,,,,,PHI:11279; PHI:11280; PHI:11282; PHI:11284,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18210,PHI:11284,UniProt,A0A0B6XPF7,GenBank,AXP71580,,,64,rsh,,,,,,PHI:11279; PHI:11280; PHI:11282; PHI:11283,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,(P)ppGpp synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18211,PHI:11282,UniProt,W8TMV6,GenBank,AUS75139,,,MRSA107,relP,,,,,,PHI:11283; PHI:11284,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,(P)ppGpp synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18212,PHI:11283,,no data found,GenBank,OBY01590,,,137/93G,relQ,,,,,,PHI:11282; PHI:11284,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,GTP pyrophosphokinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18213,PHI:11284,UniProt,A0A0B6XPF7,GenBank,AXP71580,,,64,rsh,,,,,,PHI:11282; PHI:11283,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,(P)ppGpp synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18214,PHI:11285,UniProt,P09616,GenBank,CAA25801,,,WOOD 46,hla,,,,,,,1280,Staphylococcus aureus,367830,USA300,infective endocarditis,primates,9606,Homo sapiens (related: human),EA.hy 926 cell line,,,endothelial cell,alpha-hemolysin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33843450,PubMed,10.1080/21505594.2021.1910455,Virulence. 2021 Dec;12(1):1186-1198,lorena.tuchscherrdehauschopp@med.uni-jena.de,"In cell culture infection models, we found that the absence of psmαβ decreased the host cell lysis and increased staphylococcal long-term survival.",A Siegmund 2021,2021,7 genes,Siegmund-2021-Intracellular persistence of Sta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18215,PHI:11286,UniProt,Q50584,GenBank,CCP44287,,,H37Rv,Rv1523,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,methyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,heterologous expression,,,YVS,33777836,PubMed,10.3389/fcimb.2021.622487,Front Cell Infect Microbiol. 2021 Mar 12;11:622487,nzehtesham@gmail.com,Macrophages infected with recombinant M. smegmatis induced necrotic cell death and modulated the host immune responses.,S Ali 2021,2021,1 gene,Ali-2021-The M. tuberculosis Rv1523 Methyltran,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18216,PHI:11287,UniProt,Q56405,GenBank,AAA25276,,,Lm74,cadC,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,stomach; spleen; liver,cadmium resistance transcriptional regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31955655,PubMed,10.1080/19490976.2020.1712983,Gut Microbes. 2020 Jul 3;11(4):868-881,didier@ibmc.up.pt,CadC played no critical role in Lm persistence within the gastrointestinal tract.,R Pombinho 2020,2020,1 gene,Pombinho-2020-Virulence gene repression promot,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18217,PHI:11288,,no data found,,,,,,mgtQ,,Asp2 and Glu5 to Ala substitution,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN (Nramp11/1),,,,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33849981,PubMed,10.1128/mBio.03376-20,mBio. 2021 Apr 13;12(2):e03376-20,eunjinlee@korea.ac.kr,The Salmonella strain with the Asp2 and Glu5 to Ala substitution in mgtQ was attenuated for virulence in mice compared to wild type.,E Choi 2021,2021,1 gene,Choi-2021-A Translation-Aborting Small Open Re,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18218,PHI:11289,UniProt,Q0WXM3,GenBank,BAE98264,,,Mel02010,FOW2,,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best; cv. S22; cv. SEL22; cv. DVRT1,,,leaf,Zn(II)2Cys6 transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,28674943,PubMed,10.1007/s12033-017-0022-y,Mol Biotechnol. 2017 Aug;59(8):343-352,sudesh@ciab.res.in,The host-induced posttranscriptional gene silencing of pathogenicity genes in transgenic tomato plants enhanced their resistance to vascular wilt disease caused by Fusarium oxysporum.,P Bharti 2017,2017,2 genes,Bharti-2017-Host-Induced Silencing of Pathogen,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18219,PHI:11290,UniProt,Q873Z8,GenBank,AF484941_1,,,,chsV,,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best; cv. S22; cv. SEL22; cv. DVRT1,,,leaf,chitin synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,28674943,PubMed,10.1007/s12033-017-0022-y,Mol Biotechnol. 2017 Aug;59(8):343-352,sudesh@ciab.res.in,The host-induced posttranscriptional gene silencing of pathogenicity genes in transgenic tomato plants enhanced their resistance to vascular wilt disease caused by Fusarium oxysporum.,P Bharti 2017,2017,2 genes,Bharti-2017-Host-Induced Silencing of Pathogen,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18220,PHI:11291,UniProt,A0A0H3P014,GenBank,CCF76772,,,SL1344,spvA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33816345,PubMed,10.3389/fcimb.2021.641412,Front Cell Infect Microbiol. 2021 Mar 18;11:641412,liyuanyuan@suda.edu.cn,"SpvB, a pSLTencoded cytotoxic protein secreted by Salmonella pathogenicity island-2 T3SS, was associated with enhanced Salmonella survival and intracellular replication.",S Yang 2021,2021,3 genes,Yang-2021-Salmonella Effector SpvB Inhibits NF,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18221,PHI:11292,UniProt,H9L477,GenBank,AAL23530,,,LT2,spvB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33816345,PubMed,10.3389/fcimb.2021.641412,Front Cell Infect Microbiol. 2021 Mar 18;11:641412,liyuanyuan@suda.edu.cn,"SpvB, a pSLTencoded cytotoxic protein secreted by Salmonella pathogenicity island-2 T3SS, was associated with enhanced Salmonella survival and intracellular replication.",S Yang 2021,2021,3 genes,Yang-2021-Salmonella Effector SpvB Inhibits NF,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18222,PHI:11293,UniProt,A0A0H3NYG4,GenBank,CCF76775,,,SL1344,spvD,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33816345,PubMed,10.3389/fcimb.2021.641412,Front Cell Infect Microbiol. 2021 Mar 18;11:641412,liyuanyuan@suda.edu.cn,"SpvB, a pSLTencoded cytotoxic protein secreted by Salmonella pathogenicity island-2 T3SS, was associated with enhanced Salmonella survival and intracellular replication.",S Yang 2021,2021,3 genes,Yang-2021-Salmonella Effector SpvB Inhibits NF,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18223,PHI:11291,UniProt,A0A0H3P014,GenBank,CCF76772,,,SL1344,spvA,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,primates,9606,Homo sapiens (related: human),HEK293T cell line,,,HEK-293T cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33816345,PubMed,10.3389/fcimb.2021.641412,Front Cell Infect Microbiol. 2021 Mar 18;11:641412,liyuanyuan@suda.edu.cn,"SpvB, a pSLTencoded cytotoxic protein secreted by Salmonella pathogenicity island-2 T3SS, was associated with enhanced Salmonella survival and intracellular replication.",S Yang 2021,2021,3 genes,Yang-2021-Salmonella Effector SpvB Inhibits NF,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18224,PHI:11292,UniProt,H9L477,GenBank,AAL23530,,,LT2,spvB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,primates,9606,Homo sapiens (related: human),HEK293T cell line,,,HEK-293T cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33816345,PubMed,10.3389/fcimb.2021.641412,Front Cell Infect Microbiol. 2021 Mar 18;11:641412,liyuanyuan@suda.edu.cn,"SpvB, a pSLTencoded cytotoxic protein secreted by Salmonella pathogenicity island-2 T3SS, was associated with enhanced Salmonella survival and intracellular replication.",S Yang 2021,2021,3 genes,Yang-2021-Salmonella Effector SpvB Inhibits NF,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18225,PHI:11293,UniProt,A0A0H3NYG4,GenBank,CCF76775,,,SL1344,spvD,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,primates,9606,Homo sapiens (related: human),HEK293T cell line,,,HEK-293T cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33816345,PubMed,10.3389/fcimb.2021.641412,Front Cell Infect Microbiol. 2021 Mar 18;11:641412,liyuanyuan@suda.edu.cn,"SpvB, a pSLTencoded cytotoxic protein secreted by Salmonella pathogenicity island-2 T3SS, was associated with enhanced Salmonella survival and intracellular replication.",S Yang 2021,2021,3 genes,Yang-2021-Salmonella Effector SpvB Inhibits NF,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18226,PHI:11294,,no data found,,,,,,CgNPG1,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,uncharacterized protein,,,,reduced virulence,,yes,,,,reduced,,reduced; aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33763047,PubMed,10.3389/fmicb.2021.629387,Front Microbiol. 2021 Mar 8;12:629387,hlluo@hainanu.edu.cn,"Deletion of CgNPG1 led to changed conidia morphology, decreased mycelial growth, conidiation, conidia germination rate, appressorium formation rate, and pathogenicity of C. gloeosporioides Hb to the rubber tree.",C Liang 2021,2021,1 gene,Liang-2021-CgNPG1 as a Novel Pathogenic Gene o,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18227,PHI:11294,,no data found,,,,,,CgNPG1,,,,,,,27357,Colletotrichum acutatum,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,uncharacterized protein,,,,increased virulence (hypervirulence),,no,,,,increased,,increased,wild type,no,,,,,,,heterologous expression,,,YVS,33763047,PubMed,10.3389/fmicb.2021.629387,Front Microbiol. 2021 Mar 8;12:629387,hlluo@hainanu.edu.cn,"Deletion of CgNPG1 led to changed conidia morphology, decreased mycelial growth, conidiation, conidia germination rate, appressorium formation rate, and pathogenicity of C. gloeosporioides Hb to the rubber tree.",C Liang 2021,2021,1 gene,Liang-2021-CgNPG1 as a Novel Pathogenic Gene o,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18228,PHI:11295,UniProt,V5VI79,GenBank,AIL80324,,,AB030,relA (ABUW_3302),,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32229531,PubMed,10.1128/JB.00045-20. Print 2020 May 27,J Bacteriol. 2020 May 27;202(12):e00045-20,prather@emory.edu,The ΔrelA mutant exhibited reduced virulence.,M Pérez-Varela 2020,2020,1 gene,Pérez-Varela-2020-Characterization of RelA in,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18229,PHI:11296,UniProt,Q2FWE3,GenBank,ABD31387,,,NCTC 8325,ptpB,,,,,,,1280,Staphylococcus aureus,,SA564,pneumonia,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,low molecular weight protein-tyrosine-phosphatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33799337,PubMed,10.3390/cells10030645,Cells. 2021 Mar 14;10(3):645,virginie.molle@umontpellier.fr,The SA564 DptpB mutant displayed markedly reduced bacterial loads in liver and kidney tissues in a murine S. aureus abscess model when compared to the wild type.,M I Elhawy 2021,2021,1 gene,Elhawy-2021-The Phosphoarginine Phosphatase Pt,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18230,PHI:11296,UniProt,Q2FWE3,GenBank,ABD31387,,,NCTC 8325,ptpB,,,,,,,1280,Staphylococcus aureus,,SA564,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; kidney,low molecular weight protein-tyrosine-phosphatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33799337,PubMed,10.3390/cells10030645,Cells. 2021 Mar 14;10(3):645,virginie.molle@umontpellier.fr,The SA564 DptpB mutant displayed markedly reduced bacterial loads in liver and kidney tissues in a murine S. aureus abscess model when compared to the wild type.,M I Elhawy 2021,2021,1 gene,Elhawy-2021-The Phosphoarginine Phosphatase Pt,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18231,PHI:11297,UniProt,G5EHH9,GenBank,EAQ71124,,,70-15,MoSVP (MGG_02778),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Ina168,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Nigrate,,,leaf,small putative secreted protein,,,,reduced virulence,,no,,yes,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31560822,PubMed,10.1111/mpp.12869. Epub 2019 Sep 27,Mol Plant Pathol. 2019 Dec;20(12):1682-1695,hs206173@nodai.ac.jp,Knockout of MoSVP resulted in a reduction in pathogenicity.,M Shimizu 2019,2019,1 gene,Shimizu-2019-RNA-Seq of in planta-expressed Ma,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18232,PHI:11298,UniProt,Q9F8C5,GenBank,AIK75166,,,GBS6,czcD,,,,,,,1311,Streptococcus agalactiae,,874391,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; bladder,Zn exporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34011683,PubMed,10.1128/mSphere.00105-21,mSphere. 2021 May 19;6(3):e00105-21,g.ulett@griffith.edu.au,"The czcD-sczA Zn management axis supported virulence in the blood, heart, liver, and bladder.",M J Sullivan 2021,2021,2 genes,Sullivan-2021-Cellular Management of Zinc in G,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18233,PHI:11298,UniProt,Q9F8C5,GenBank,AIK75166,,,GBS6,czcD,,,,,,,1311,Streptococcus agalactiae,,874391,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; blood; heart; lung; kidney; spleen,Zn exporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34011683,PubMed,10.1128/mSphere.00105-21,mSphere. 2021 May 19;6(3):e00105-21,g.ulett@griffith.edu.au,"The czcD-sczA Zn management axis supported virulence in the blood, heart, liver, and bladder.",M J Sullivan 2021,2021,2 genes,Sullivan-2021-Cellular Management of Zinc in G,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18234,PHI:11299,,no data found,,,,,,sczA,,,,,,,1311,Streptococcus agalactiae,,874391,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; heart,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34011683,PubMed,10.1128/mSphere.00105-21,mSphere. 2021 May 19;6(3):e00105-21,g.ulett@griffith.edu.au,"The czcD-sczA Zn management axis supported virulence in the blood, heart, liver, and bladder.",M J Sullivan 2021,2021,2 genes,Sullivan-2021-Cellular Management of Zinc in G,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18235,PHI:11299,,no data found,,,,,,sczA,,,,,,,1311,Streptococcus agalactiae,,874391,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; bladder,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34011683,PubMed,10.1128/mSphere.00105-21,mSphere. 2021 May 19;6(3):e00105-21,g.ulett@griffith.edu.au,"The czcD-sczA Zn management axis supported virulence in the blood, heart, liver, and bladder.",M J Sullivan 2021,2021,2 genes,Sullivan-2021-Cellular Management of Zinc in G,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18236,PHI:11298,UniProt,Q9F8C5,GenBank,AIK75166,,,GBS6,czcD,,,,,,,1311,Streptococcus agalactiae,,874391,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),J774.1 cell line,,,macrophage,Zn exporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34011683,PubMed,10.1128/mSphere.00105-21,mSphere. 2021 May 19;6(3):e00105-21,g.ulett@griffith.edu.au,"The czcD-sczA Zn management axis supported virulence in the blood, heart, liver, and bladder.",M J Sullivan 2021,2021,2 genes,Sullivan-2021-Cellular Management of Zinc in G,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18237,PHI:11299,,no data found,,,,,,sczA,,,,,,,1311,Streptococcus agalactiae,,874391,pneumonia; meningitis,primates,9606,Homo sapiens (related: human),U-937 cell line,,,macrophage,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34011683,PubMed,10.1128/mSphere.00105-21,mSphere. 2021 May 19;6(3):e00105-21,g.ulett@griffith.edu.au,"The czcD-sczA Zn management axis supported virulence in the blood, heart, liver, and bladder.",M J Sullivan 2021,2021,2 genes,Sullivan-2021-Cellular Management of Zinc in G,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18238,PHI:11300,UniProt,B8NTK5,GenBank,QMW33608,,,NRRL3357,rtt109,chromosome 6,,,,,,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,histone acetyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; sodium chloride; methyl methanesulfonate (MMS); hydrogen peroxide,Congo red: CHEBI:34653; sodium chloride: CHEBI:26710; methyl methanesulfonate (MMS): CHEBI:25255; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33823938,PubMed,10.1186/s43008-021-00060-4,IMA Fungus. 2021 Apr 7;12(1):9,wshyyl@sina.com,The Δrtt109 strain was extremely sensitive to DNA damage stress.,R Sun 2021,2021,1 gene,Sun-2021-The Fungi-specific histone Acetyltran,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18239,PHI:11300,UniProt,B8NTK5,GenBank,QMW33608,,,NRRL3357,rtt109,chromosome 6,H3K9Q,,,,,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,histone acetyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,Congo red; sodium chloride; methyl methanesulfonate (MMS); hydrogen peroxide,Congo red: CHEBI:34653; sodium chloride: CHEBI:26710; methyl methanesulfonate (MMS): CHEBI:25255; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33823938,PubMed,10.1186/s43008-021-00060-4,IMA Fungus. 2021 Apr 7;12(1):9,wshyyl@sina.com,The Δrtt109 strain was extremely sensitive to DNA damage stress.,R Sun 2021,2021,1 gene,Sun-2021-The Fungi-specific histone Acetyltran,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18240,PHI:11300,UniProt,B8NTK5,GenBank,QMW33608,,,NRRL3357,rtt109,chromosome 6,H3K9R and H3K9A,,,,,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,histone acetyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; sodium chloride; methyl methanesulfonate (MMS); hydrogen peroxide,Congo red: CHEBI:34653; sodium chloride: CHEBI:26710; methyl methanesulfonate (MMS): CHEBI:25255; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33823938,PubMed,10.1186/s43008-021-00060-4,IMA Fungus. 2021 Apr 7;12(1):9,wshyyl@sina.com,The Δrtt109 strain was extremely sensitive to DNA damage stress.,R Sun 2021,2021,1 gene,Sun-2021-The Fungi-specific histone Acetyltran,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18241,PHI:11301,,no data found,,,,,,HPnc4160,,,,,,,210,Helicobacter pylori,,ATCC 43504,gastric infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,stomach,small non-coding RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33837194,PubMed,10.1038/s41467-021-22317-7,Nat Commun. 2021 Apr 9;12(1):2085,mimuro@biken.osaka-u.ac.jp,"Mutant strains with HPnc4160 deficiency displayed increased colonization ability of the mouse stomach, in comparison with the wild-type strain.",R Kinoshita-Daitoku 2021,2021,1 gene,Kinoshita-Daito-2021-A bacterial small RNA reg,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18242,PHI:11302,UniProt,P0A1I3,GenBank,AAL21776,,,LT2,inva,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,macrophage,invasion protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30680603,PubMed,10.1007/s42770-019-00042-0,Braz J Microbiol. 2019 Apr;50(2):539-546,guedesufmg@gmail.com,"The early cytotoxic effect was Salmonella pathogenicity island (SPI)-dependent, in which log-phase WT strains were more efficient (p < 0.01) than the invA mutant strain at inducing the death of macrophages.",C E R Pereira 2019,2019,1 gene,Pereira-2019-Phenotypic characterization of sw,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18243,PHI:11302,UniProt,P0A1I3,GenBank,AAL21776,,,LT2,inva,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,salmonellosis,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,macrophage,invasion protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30680603,PubMed,10.1007/s42770-019-00042-0,Braz J Microbiol. 2019 Apr;50(2):539-546,guedesufmg@gmail.com,"The early cytotoxic effect was Salmonella pathogenicity island (SPI)-dependent, in which log-phase WT strains were more efficient (p < 0.01) than the invA mutant strain at inducing the death of macrophages.",C E R Pereira 2019,2019,1 gene,Pereira-2019-Phenotypic characterization of sw,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18244,PHI:11303,,no data found,GenBank,AAT03304,,,4b F2365,lysR (LMOf2365_0522),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32179628,PubMed,10.1128/JB.00087-20,J Bacteriol. 2020 Apr 27;202(10):e00087-20,abdelhamed@cvm.msstate.edu,L. monocytogenes strain lacking lysR displayed significant reductions in cell invasion of and adhesion to Caco-2 cells.,H Abdelhamed 2020,2020,1 gene,Abdelhamed-2020-Contributions of a LysR Transc,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18245,PHI:11303,,no data found,GenBank,AAT03304,,,4b F2365,lysR (LMOf2365_0522),,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32179628,PubMed,10.1128/JB.00087-20,J Bacteriol. 2020 Apr 27;202(10):e00087-20,abdelhamed@cvm.msstate.edu,The deletion of lysR also attenuated the virulence of L. monocytogenes in mice following oral and intraperitoneal inoculation.,H Abdelhamed 2020,2020,1 gene,Abdelhamed-2020-Contributions of a LysR Transc,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18246,PHI:11304,UniProt,J4UFF8,GenBank,EJP61242,,,ARSEF 2860,BbTFO1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,p53-like transcription factor,,,,reduced virulence,,,,,,reduced,,,,no,Congo red; NaCl; menadione; H2O2,Congo red: CHEBI:34653; NaCl: CHEBI:26710; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33788872,PubMed,10.1371/journal.pone.0249350,PLoS One. 2021 Mar 31;16(3):e0249350,qiulei.2005@163.com,"ΔBbTFO1 also displayed defective conidial germination, virulence and heat resistance.",J J Wang 2021,2021,1 gene,"Wang-2021-A p53-like transcription factor, BbT",BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18247,PHI:11305,UniProt,A0A063BZ78,GenBank,GAO17620,,,IPU010,UvEC1,,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,putative ester cyclase,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; sorbitol; SDS; Congo red; calcofluor white,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,33920773,PubMed,10.3390/ijms22084069,Int J Mol Sci. 2021 Apr 15;22(8):4069,junbinhuang@mail.hzau.edu.cn,UvEC1 was required for response to hyperosmotic and oxidative stresses and for maintenance of cell wall integrity.,X Chen 2021,2021,1 gene,Chen-2021-Quantitative Proteomics Analysis Rev,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18248,PHI:11306,UniProt,Q5KG95,GenBank,AAW43798,,,JEC21,Cbc1 (CNE04400),chromosome 5,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,"cyclin-dependent protein kinase regulator, putative",,,,loss of pathogenicity,,,,,,,,reduced; aberrant,,no,SDS; H2O2; sorbitol; CdSO4; MMS; DTT,SDS: CHEBI:8984; H2O2: CHEBI:16240; sorbitol: CHEBI:30911; CdSO4: CHEBI:50292; MMS: CHEBI:25255; dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,33165808,PubMed,10.1007/s11427-020-1697-3,Sci China Life Sci. 2020 Nov 3,wanglq@im.ac.cn,Virulence assessment using the murine model of cryptococcosis revealed that the cbc1 mutant is avirulent.,P Hu 2020,2020,1 gene,Hu-2020-A cyclin protein governs the infectiou,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18249,PHI:11307,UniProt,O51189,GenBank,AAC66563,,,B31,BpiP (BB0167),,,,,,,139,Borreliella burgdorferi,,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin; lymph node; spleen; heart; bladder; joint; macrophage; dendritic cell,Borrelia peptidoglycan interacting protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; vancomycin,NaCl: CHEBI:26710; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,33882111,PubMed,10.1371/journal.ppat.1009535,PLoS Pathog. 2021 Apr 21;17(4):e1009535,j.seshu@utsa.edu,"BpiP mutant revealed increased sensitivity to vancomycin, osmotic stress, lysosomal extracts, human antimicrobial peptide cathelicidin-LL37, complement-dependent killing in the presence of day 14 post-infection mouse serum.",Y Chen 2021,2021,1 gene,Chen-2021-Borrelia peptidoglycan interacting P,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18250,PHI:11307,UniProt,O51189,GenBank,AAC66563,,,B31,BpiP (BB0167),,,,,,,139,Borreliella burgdorferi,,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin; lymph node; spleen; macrophage; dendritic cell,Borrelia peptidoglycan interacting protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; vancomycin,NaCl: CHEBI:26710; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,33882111,PubMed,10.1371/journal.ppat.1009535,PLoS Pathog. 2021 Apr 21;17(4):e1009535,j.seshu@utsa.edu,"BpiP mutant revealed increased sensitivity to vancomycin, osmotic stress, lysosomal extracts, human antimicrobial peptide cathelicidin-LL37, complement-dependent killing in the presence of day 14 post-infection mouse serum.",Y Chen 2021,2021,1 gene,Chen-2021-Borrelia peptidoglycan interacting P,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18251,PHI:11307,UniProt,O51189,GenBank,AAC66563,,,B31,BpiP (BB0167),,,,,,,139,Borreliella burgdorferi,,B31 A3,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,Borrelia peptidoglycan interacting protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; vancomycin,NaCl: CHEBI:26710; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,33882111,PubMed,10.1371/journal.ppat.1009535,PLoS Pathog. 2021 Apr 21;17(4):e1009535,j.seshu@utsa.edu,"BpiP mutant revealed increased sensitivity to vancomycin, osmotic stress, lysosomal extracts, human antimicrobial peptide cathelicidin-LL37, complement-dependent killing in the presence of day 14 post-infection mouse serum.",Y Chen 2021,2021,1 gene,Chen-2021-Borrelia peptidoglycan interacting P,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18252,PHI:11308,UniProt,G4ZRQ8,GenBank,EGZ13867,,,P6497,Avr1b-1,,,,,,,67593,Phytophthora sojae,1094619,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams; cv. L77-1863,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33815332,PubMed,10.3389/fmicb.2021.645331,Front Microbiol. 2021 Mar 18;12:645331,Brett.Tyler@oregonstate.edu,RXLR effector gene Avr1b-1 was not required for the full virulence of strain P7063.,B Gu 2021,2021,1 gene,Gu-2021-Transcriptional Variability Associated,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18253,PHI:11308,UniProt,G4ZRQ8,GenBank,EGZ13867,,,P6497,Avr1b-1,,,,,,,67593,Phytophthora sojae,,P7063,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams; cv. L77-1863,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33815332,PubMed,10.3389/fmicb.2021.645331,Front Microbiol. 2021 Mar 18;12:645331,Brett.Tyler@oregonstate.edu,RXLR effector gene Avr1b-1 was not required for the full virulence of strain P7063.,B Gu 2021,2021,1 gene,Gu-2021-Transcriptional Variability Associated,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18254,PHI:11309,UniProt,B2HSV2,GenBank,ACC41126,,,M,ppe31 (MMAR_2683),,,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,PPE family protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33928042,PubMed,10.3389/fcimb.2021.629836,Front Cell Infect Microbiol. 2021 Apr 13;11:629836,haibo_zhou2003@163.com,Macrophages infected with the ppe31 Mm mutant strain caused a reduced inflammatory mediator expressions.,S Feng 2021,2021,2 genes,Feng-2021-Mycobacterium PPE31 Contributes to H,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18255,PHI:11309,UniProt,B2HSV2,GenBank,ACC41126,,,M,ppe31 (MMAR_2683),,,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,PPE family protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33928042,PubMed,10.3389/fcimb.2021.629836,Front Cell Infect Microbiol. 2021 Apr 13;11:629836,haibo_zhou2003@163.com,Macrophages infected with the ppe31 Mm mutant strain caused a reduced inflammatory mediator expressions.,S Feng 2021,2021,2 genes,Feng-2021-Mycobacterium PPE31 Contributes to H,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18256,PHI:11309,UniProt,B2HSV2,GenBank,ACC41126,,,M,ppe31 (MMAR_2683),,,,,,,1781,Mycobacterium marinum,216594,M,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,PPE family protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33928042,PubMed,10.3389/fcimb.2021.629836,Front Cell Infect Microbiol. 2021 Apr 13;11:629836,haibo_zhou2003@163.com,Macrophages infected with the ppe31 Mm mutant strain caused a reduced inflammatory mediator expressions.,S Feng 2021,2021,2 genes,Feng-2021-Mycobacterium PPE31 Contributes to H,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18257,PHI:11310,UniProt,L0T7Y7,GenBank,CCP44573,,,H37Rv,ppe31 (rv1807),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,PPE family protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33928042,PubMed,10.3389/fcimb.2021.629836,Front Cell Infect Microbiol. 2021 Apr 13;11:629836,haibo_zhou2003@163.com,Macrophages infected with the ppe31 Mm mutant strain caused a reduced inflammatory mediator expressions.,S Feng 2021,2021,2 genes,Feng-2021-Mycobacterium PPE31 Contributes to H,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18258,PHI:11310,UniProt,L0T7Y7,GenBank,CCP44573,,,H37Rv,ppe31 (rv1807),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,PPE family protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33928042,PubMed,10.3389/fcimb.2021.629836,Front Cell Infect Microbiol. 2021 Apr 13;11:629836,haibo_zhou2003@163.com,Macrophages infected with the ppe31 Mm mutant strain caused a reduced inflammatory mediator expressions.,S Feng 2021,2021,2 genes,Feng-2021-Mycobacterium PPE31 Contributes to H,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18259,PHI:11311,UniProt,Q7A5Q2,GenBank,BAB42481,,,N315,PstS,,,,,,PHI:11312; PHI:11313; PHI:11314,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; heart; kidney,phosphate-binding protein/ thioredoxine reductase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32205403,PubMed,10.1128/IAI.00102-20,Infect Immun. 2020 May 20;88(6):e00102-20,kehlfie@illinois.edu,Overexpression of pstSCAB decreased the virulence of S. aureus and renders it more sensitive to nutritional immunity.,J L Kelliher 2020,2020,4 genes,Kelliher-2020-Disruption of Phosphate Homeosta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18260,PHI:11312,,no data found,GenBank,VFS05436,,,NCTC8532,PstC,,,,,,PHI:11311; PHI:11313; PHI:11314,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; heart; kidney,"ABC-type phosphate transport system, permease component",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32205403,PubMed,10.1128/IAI.00102-20,Infect Immun. 2020 May 20;88(6):e00102-20,kehlfie@illinois.edu,Overexpression of pstSCAB decreased the virulence of S. aureus and renders it more sensitive to nutritional immunity.,J L Kelliher 2020,2020,4 genes,Kelliher-2020-Disruption of Phosphate Homeosta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18261,PHI:11313,,no data found,GenBank,KFL07504,,,CDC 73-57501,PstA,,,,,,PHI:11311; PHI:11312; PHI:11314,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; heart; kidney,"phosphate ABC transporter, permease protein",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32205403,PubMed,10.1128/IAI.00102-20,Infect Immun. 2020 May 20;88(6):e00102-20,kehlfie@illinois.edu,Overexpression of pstSCAB decreased the virulence of S. aureus and renders it more sensitive to nutritional immunity.,J L Kelliher 2020,2020,4 genes,Kelliher-2020-Disruption of Phosphate Homeosta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18262,PHI:11314,UniProt,Q2FYQ0,GenBank,ABD30480,,,NCTC 8325,PstB,,,,,,PHI:11311; PHI:11312; PHI:11313,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; heart; kidney,phosphate import ATP-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,32205403,PubMed,10.1128/IAI.00102-20,Infect Immun. 2020 May 20;88(6):e00102-20,kehlfie@illinois.edu,Overexpression of pstSCAB decreased the virulence of S. aureus and renders it more sensitive to nutritional immunity.,J L Kelliher 2020,2020,4 genes,Kelliher-2020-Disruption of Phosphate Homeosta,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18263,PHI:11315,UniProt,Q83A39,GenBank,AAO91556,,,RSA 493,EirA (CBU2072),,,,,,,777,Coxiella burnetii,,RSA 439,Q fever,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,hypothetical exported protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: full; gene complementation,,,YVS,32205404,PubMed,10.1128/IAI.00913-19,Infect Immun. 2020 May 20;88(6):e00913-19,hnewton@unimelb.edu.au,EirA was not required for the intracellular viability of C. burnetii.,M Kuba 2020,2020,1 gene,Kuba-2020-EirA Is a Novel Protein Essential fo,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18264,PHI:11315,UniProt,Q83A39,GenBank,AAO91556,,,RSA 493,EirA (CBU2072),,,,,,,777,Coxiella burnetii,,RSA 439,Q fever,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,hypothetical exported protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: full; gene complementation,,,YVS,32205404,PubMed,10.1128/IAI.00913-19,Infect Immun. 2020 May 20;88(6):e00913-19,hnewton@unimelb.edu.au,EirA was not required for the intracellular viability of C. burnetii.,M Kuba 2020,2020,1 gene,Kuba-2020-EirA Is a Novel Protein Essential fo,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18265,PHI:11315,UniProt,Q83A39,GenBank,AAO91556,,,RSA 493,EirA (CBU2072),,,,,,,777,Coxiella burnetii,,RSA 439,Q fever,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical exported protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: full; gene complementation,,,YVS,32205404,PubMed,10.1128/IAI.00913-19,Infect Immun. 2020 May 20;88(6):e00913-19,hnewton@unimelb.edu.au,EirA was not required for the intracellular viability of C. burnetii.,M Kuba 2020,2020,1 gene,Kuba-2020-EirA Is a Novel Protein Essential fo,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18266,PHI:11316,,no data found,,,,,,ryhB-1,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33803635,PubMed,10.3390/microorganisms9030635,Microorganisms. 2021 Mar 18;9(3):635,lcalderon@unab.cl,Deletion of RyhB-1 and/or RyhB-2 resulted in increased intracellular survival and faster replication within macrophages.,D Peñaloza 2021,2021,2 genes,Peñaloza-2021-The Small RNA RyhB Homologs from,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18267,PHI:11317,,no data found,,,,,,ryhB-2,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33803635,PubMed,10.3390/microorganisms9030635,Microorganisms. 2021 Mar 18;9(3):635,lcalderon@unab.cl,Deletion of RyhB-1 and/or RyhB-2 resulted in increased intracellular survival and faster replication within macrophages.,D Peñaloza 2021,2021,2 genes,Peñaloza-2021-The Small RNA RyhB Homologs from,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18268,PHI:11316,,no data found,,,,,,ryhB-1,,,,,,PHI:11317,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33803635,PubMed,10.3390/microorganisms9030635,Microorganisms. 2021 Mar 18;9(3):635,lcalderon@unab.cl,Deletion of RyhB-1 and/or RyhB-2 resulted in increased intracellular survival and faster replication within macrophages.,D Peñaloza 2021,2021,2 genes,Peñaloza-2021-The Small RNA RyhB Homologs from,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18269,PHI:11317,,no data found,,,,,,ryhB-2,,,,,,PHI:11316,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33803635,PubMed,10.3390/microorganisms9030635,Microorganisms. 2021 Mar 18;9(3):635,lcalderon@unab.cl,Deletion of RyhB-1 and/or RyhB-2 resulted in increased intracellular survival and faster replication within macrophages.,D Peñaloza 2021,2021,2 genes,Peñaloza-2021-The Small RNA RyhB Homologs from,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18270,PHI:11318,UniProt,T0KEV9,GenBank,EQB51493,,,Cg-14,CgEnd3,,,,,,,474922,Colletotrichum gloeosporioides,,CFCC80308,fruit rot,eudicots,3690,Populus x canadensis (related: carolina poplar),,,,leaf,endocytosis protein 3,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,reduced,no,calcofluor white; NaCl; sorbitol; H2O2; fludioxonil; difenoconazole,calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; fludioxonil: CAS:131341-86-1; difenoconazole: CHEBI:81760,,,,,gene deletion: full; gene complementation,,,YVS,33919762,PubMed,10.3390/ijms22084029,Int J Mol Sci. 2021 Apr 14;22(8):4029,chengmt@bjfu.edu.cn,"The ΔCgEnd3 showed deficient appressorium formation, melanization, turgor pressure accumulation, penetration ability of appressorium, cellophane membrane penetration, and pathogenicity.",X Wang 2021,2021,1 gene,"Wang-2021-CgEnd3 Regulates Endocytosis, Appres",BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18271,PHI:11319,UniProt,A0QPF9,GenBank,ABB72064,,,MC2 155,RmlA,,T12D,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,thymidylyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,YVS,33868202,PubMed,10.3389/fmicb.2021.643951,Front Microbiol. 2021 Mar 31;12:643951,taosc@sjtu.edu.cn,Virulence of RmlA T12D mutant was attenuated in a macrophage model.,D Qu 2021,2021,1 gene,Qu-2021-Mycobacterium tuberculosis Thymidylylt,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18272,PHI:11319,UniProt,A0QPF9,GenBank,ABB72064,,,MC2 155,RmlA,,T12A,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,thymidylyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,heterologous expression,,,YVS,33868202,PubMed,10.3389/fmicb.2021.643951,Front Microbiol. 2021 Mar 31;12:643951,taosc@sjtu.edu.cn,Virulence of RmlA T12D mutant was attenuated in a macrophage model.,D Qu 2021,2021,1 gene,Qu-2021-Mycobacterium tuberculosis Thymidylylt,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18273,PHI:11320,,no data found,,,,,,cap,,,,,,,738,Glaesserella parasuis,,HS069,Glasser's disease,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,alveolar macrophage,capsule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32094250,PubMed,10.1128/IAI.00879-19,Infect Immun. 2020 Apr 20;88(5):e00879-19,susan.brockmeier@ars.usda.gov,"HS069Δcap produced more robust biofilm and adhered equivalently to 3D4/31 cells; however, it was unable to persistently colonize the nasal cavity of inoculated pigs. (AC note, The entirety of the capsule locus was deleted from neuA_3 to etk as indicated in Fig1A. This is a multi-gene deletion).",K C Eberle 2020,2020,1 gene,Eberle-2020-Generation and Evaluation of a Gla,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18274,PHI:11321,UniProt,A0A162ZXY0,GenBank,KZM20872,,,ArDII,arf-bar,,,,,,,5454,Ascochyta rabiei,,ArD2,Ascochyta blight (chickpea),eudicots,3827,Cicer arietinum (related: Chickpea),Pusa 362,,,leaf,"F-BAR domain protein, metal ion binding",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33999937,PubMed,10.1371/journal.pgen.1009137,PLoS Genet. 2021 May 17;17(5):e1009137,pkv@nipgr.ac.in,The loss-of-function of ArF-BAR gene resulted in delayed formation of apical septum in fungal cells near growing hyphal tip that is crucial for host penetration.,M Sinha 2021,2021,1 gene,Sinha-2021-Modulation of fungal virulence thro,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18275,PHI:11321,UniProt,A0A162ZXY0,GenBank,KZM20872,,,ArDII,arf-bar,,mutation in F-BAR domain (Δarf-bar/ArF-BARmut1); C1 domain (Δarf-bar/ArF-BARmut2),,,,,5454,Ascochyta rabiei,,ArD2,Ascochyta blight (chickpea),eudicots,3827,Cicer arietinum (related: Chickpea),Pusa 362,,,leaf,"F-BAR domain protein, metal ion binding",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33999937,PubMed,10.1371/journal.pgen.1009137,PLoS Genet. 2021 May 17;17(5):e1009137,pkv@nipgr.ac.in,The loss-of-function of ArF-BAR gene resulted in delayed formation of apical septum in fungal cells near growing hyphal tip that is crucial for host penetration.,M Sinha 2021,2021,1 gene,Sinha-2021-Modulation of fungal virulence thro,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18276,PHI:11322,UniProt,Q0PAS9,GenBank,CAL34734,,,NCTC 11168,Cj0588,,,,,,,197,Campylobacter jejuni,354242,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,putative hemolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; heterologous gene complementation,,,YVS,32134554,PubMed,10.1111/cmi.13199,Cell Microbiol. 2020 Jul;22(7):e13199,agnieszka_salamaszynska_guz@sggw.pl,The traits impaired in C. jejuni null strains could be rescued by complementation not only with the original cj0588 (tlyAI) but also with a mycobacterial tlyAII gene.,A Sałamaszynska-Guz 2020,2020,1 gene,Salamaszynska-G-2020-Virulence properties of C,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18277,PHI:11323,UniProt,F8SA27,GenBank,AEH25938,,,,PKAc,,,,,,,5599,Alternaria alternata,,,brown spot,eudicots,23211,Pyrus communis (related: Pear),cv. Zaosu,,,fruit,cyclic adenosine monophosphate-dependent protein kinase A catalytic subunit,,,,reduced virulence,,yes,,,,,,reduced,reduced,no,NaCl; sorbitol; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33968101,PubMed,10.3389/fpls.2021.642601,Front Plant Sci. 2021 Apr 21;12:642601,lyc@gsau.edu.cn,"AaPKAc was required for the hypha growth, biomass, pathogenicity, and toxin production of A. alternata.",M Zhang 2021,2021,1 gene,Zhang-2021-AaPKAc Regulates Differentiation of,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18278,PHI:11324,UniProt,B2VY78,GenBank,EDU44891,,,Pt-1C-BFP,ttcA,,,,,,,45151,Pyrenophora tritici-repentis,,M4,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Eagle Rock,,,leaf,hybrid polyketide synthase (PKS)-nonribosomal peptide synthase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,31698543,PubMed,10.1111/1462-2920.14854,Environ Microbiol. 2019 Dec;21(12):4875-4886,yitheng.chooi@uwa.edu.au,Triticones do not contribute to pathogenicity during wheat infection.,C Rawlinson 2019,2019,1 gene,Rawlinson-2019-The identification and deletion,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18279,PHI:11325,UniProt,A0A8H7MAE0,GenBank,MK410883,,,,Avr4-2,,,,,,,685502,Pseudocercospora fuligena,,,black leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector (plant avirulence determinant),,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,33962956,PubMed,10.1126/sciadv.abe0809,Sci Adv. 2021 May 7;7(19):eabe0809,istergiopoulos@ucdavis.edu,"PfAvr4-2 interacts with highly de-esterified pectin in the plant's middle lamellae or primary cell walls and interferes with Ca2+-mediated cross-linking at cell-cell junction zones, thus loosening the plant cell wall structure and synergizing the activity of pathogen secreted endo-polygalacturonases.",L H Chen 2021,2021,1 gene,Chen-2021-A diverse member of the fungal Avr4,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18280,PHI:11326,,no data found,,,,,,Fol-milR1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,root; leaf,small RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33960431,PubMed,10.1111/nph.17436,New Phytol. 2021 May 7,Katherine.Borkovich@ucr.edu,The knockout strain ΔFol-milR1 displayed attenuated pathogenicity to the susceptible tomato cultivar Moneymaker.,H M Ji 2021,2021,1 gene,"Ji-2021-Fol-milR1, a pathogenicity factor of F",BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18281,PHI:11326,,no data found,,,,,,Fol-milR1,,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici race 2 strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Motelle,,,root; leaf,small RNA,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33960431,PubMed,10.1111/nph.17436,New Phytol. 2021 May 7,Katherine.Borkovich@ucr.edu,Fol-milR1 overexpression strains exhibited enhanced virulence against the resistant cultivar Motelle.,H M Ji 2021,2021,1 gene,"Ji-2021-Fol-milR1, a pathogenicity factor of F",BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18282,PHI:11327,UniProt,Q9HTY6,GenBank,AE004933_4,,,PAO1,gshA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung; skin,glutamate--cysteine ligase,,,,reduced virulence,,,,,,,,,,no,hydrogen peroxide; NaOCl; polymyxin B; colistin; ciprofloxacin; carbenicillin; tetracycline; chloramphenicol,hydrogen peroxide: CHEBI:16240; NaOCl: CHEBI:32146; polymyxin B: CHEBI:8310; colistin: CHEBI:37943; ciprofloxacin: CHEBI:100241; carbenicillin: CHEBI:3393; tetracycline: CHEBI:27902; chloramphenicol: CHEBI:17698,,,,,gene deletion: full,,,YVS,32284368,PubMed,10.1128/IAI.00116-20,Infect Immun. 2020 May 20;88(6):e00116-20,mwhiteley3@gatech.edu,"GSH biosynthesis provided fitness benefit to P. aeruginosa in a mouse model of acute pneumonia but was dispensable in surgical wound, abscess, and acute burn wound infections.",K L Michie 2020,2020,1 gene,Michie-2020-Role of Pseudomonas aeruginosa Glu,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18283,PHI:11328,UniProt,Q880X6,GenBank,AAO56514,,,DC3000,gacA,,DC3000 Tn5::gacA mutant,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,DNA-binding response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation: full; gene complementation,,,YVS,31588661,PubMed,10.1111/mpp.12876,Mol Plant Pathol. 2020 Jan;21(1):139-144,anderje2@oregonstate.edu,"GacA was not required for virulence of DC3000 in the leaf apoplast, but was required for full virulence of DC3000 on the leaf surface, most likely due to its role in regulating motility. Tissue: leaf apoplast",M R O'Malley 2019,2019,1 gene,O'Malley-2019-A revised model for the role of,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18284,PHI:11328,UniProt,Q880X6,GenBank,AAO56514,,,DC3000,gacA,,DC3000 Tn5::gacA mutant,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,DNA-binding response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: full; gene complementation,,,YVS,31588661,PubMed,10.1111/mpp.12876,Mol Plant Pathol. 2020 Jan;21(1):139-144,anderje2@oregonstate.edu,"GacA was not required for virulence of DC3000 in the leaf apoplast, but was required for full virulence of DC3000 on the leaf surface, most likely due to its role in regulating motility.",M R O'Malley 2019,2019,1 gene,O'Malley-2019-A revised model for the role of,BATCH_106A,2021-05-01,MC,,,,,,,,,,,,,
,,Record 18285,PHI:11329,UniProt,G2X3E6,GenBank,EGY23493,,,VdLs.17,hac1,chromosome 3,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,unfolded protein response transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33921172,PubMed,10.3390/jof7040305,J Fungi (Basel). 2021 Apr 15;7(4):305,gbraus@gwdg.de,Hac1 was essential for the formation of microsclerotia as long-time survival resting structures in the field.,J Starke 2021,2021,3 genes,Starke-2021-Unfolded Protein Response and Scaf,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18286,PHI:11329,UniProt,G2X3E6,GenBank,EGY23493,,,VdLs.17,hac1,chromosome 3,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,root,unfolded protein response transcription factor,,,,reduced virulence,,,no,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33921172,PubMed,10.3390/jof7040305,J Fungi (Basel). 2021 Apr 15;7(4):305,gbraus@gwdg.de,Hac1 was essential for the formation of microsclerotia as long-time survival resting structures in the field.,J Starke 2021,2021,3 genes,Starke-2021-Unfolded Protein Response and Scaf,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18287,PHI:11330,UniProt,G2X8F6,GenBank,EGY15243,,,VdLs.17,rok1,chromosome 8,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,root,ATP-dependent RNA helicase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33921172,PubMed,10.3390/jof7040305,J Fungi (Basel). 2021 Apr 15;7(4):305,gbraus@gwdg.de,"The MAPK phosphatase Rok1 limited resting structure development of V. dahliae, but promoted growth, conidiation, and virulence.",J Starke 2021,2021,3 genes,Starke-2021-Unfolded Protein Response and Scaf,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18288,PHI:11331,,no data found,,,,,,ode1,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,oleate D12-fatty acid desaturase,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33921172,PubMed,10.3390/jof7040305,J Fungi (Basel). 2021 Apr 15;7(4):305,gbraus@gwdg.de,Single endoplasmic reticulum-associated enzymes for linoleic acid production as precursors for oxylipin signal molecules supported fungal growth but not pathogenicity.,J Starke 2021,2021,3 genes,Starke-2021-Unfolded Protein Response and Scaf,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18289,PHI:11331,,no data found,,,,,,ode1,,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,root,oleate D12-fatty acid desaturase,,,,unaffected pathogenicity,,,no,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33921172,PubMed,10.3390/jof7040305,J Fungi (Basel). 2021 Apr 15;7(4):305,gbraus@gwdg.de,Single endoplasmic reticulum-associated enzymes for linoleic acid production as precursors for oxylipin signal molecules supported fungal growth but not pathogenicity.,J Starke 2021,2021,3 genes,Starke-2021-Unfolded Protein Response and Scaf,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18290,PHI:11332,UniProt,P9WMU1,GenBank,CCP44921,,,H37Rv,Rv2145c,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bone marrow-derived macrophage,cell wall synthesis protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,34017340,PubMed,10.3389/fimmu.2021.666293,Front Immunol. 2021 May 4;12:666293,hjukim@cnu.ac.kr,Rv2145c significantly enhanced intracellular Mtb growth in BMDMs which was abrogated by STAT3 inhibition and IL-10 receptor (IL-10R) blockade.,H S Park 2021,2021,1 gene,Park-2021-Mycobacterium tuberculosis Rv2145c P,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18291,PHI:11332,UniProt,P9WMU1,GenBank,CCP44921,,,H37Rv,Rv2145c,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,cell wall synthesis protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,heterologous expression; altered gene expression/ gene regulation: overexpression,,,YVS,34017340,PubMed,10.3389/fimmu.2021.666293,Front Immunol. 2021 May 4;12:666293,hjukim@cnu.ac.kr,"The clearance of Rv2145c-expressing M. smegmatis in the lungs and spleens of mice was delayed, and these effects were abrogated by administration of anti-IL-10R antibodies.",H S Park 2021,2021,1 gene,Park-2021-Mycobacterium tuberculosis Rv2145c P,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18292,PHI:11333,UniProt,Q837Q1,GenBank,AAO80597,,,V583,rpoN,,,,,,,1351,Enterococcus faecalis,226185,V583,periapical periodontitis lesions,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand,,,heart; liver; spleen; kidney; blood,RNA polymerase sigma-54 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34006651,PubMed,10.1128/mBio.00380-21,mBio. 2021 May 18;12(3):e00380-21,lynnh@ku.edu,The rpoN mutant was significantly attenuated in both rabbit endocarditis and murine catheter-associated urinary tract infection (CAUTI).,E C Keffeler 2021,2021,2 genes,Keffeler-2021-Influence of the Alternative Sig,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18293,PHI:11333,UniProt,Q837Q1,GenBank,AAO80597,,,V583,rpoN,,,,,,,1351,Enterococcus faecalis,226185,V583,periapical periodontitis lesions,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver; spleen; kidney; blood,RNA polymerase sigma-54 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34006651,PubMed,10.1128/mBio.00380-21,mBio. 2021 May 18;12(3):e00380-21,lynnh@ku.edu,The rpoN mutant was significantly attenuated in both rabbit endocarditis and murine catheter-associated urinary tract infection (CAUTI).,E C Keffeler 2021,2021,2 genes,Keffeler-2021-Influence of the Alternative Sig,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18294,PHI:11334,UniProt,H7C6V6,GenBank,AAO81515,,,V583,ccpA,,,,,,,1351,Enterococcus faecalis,226185,V583,periapical periodontitis lesions,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand,,,heart; liver; spleen; kidney; blood,catabolite control protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34006651,PubMed,10.1128/mBio.00380-21,mBio. 2021 May 18;12(3):e00380-21,lynnh@ku.edu,The ccpA mutation in the CAUTI model showed that the absence of carbon catabolite control significantly attenuated bacterial tissue burden in this model.,E C Keffeler 2021,2021,2 genes,Keffeler-2021-Influence of the Alternative Sig,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18295,PHI:11334,UniProt,H7C6V6,GenBank,AAO81515,,,V583,ccpA,,,,,,,1351,Enterococcus faecalis,226185,V583,periapical periodontitis lesions,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver; spleen; kidney; blood,catabolite control protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34006651,PubMed,10.1128/mBio.00380-21,mBio. 2021 May 18;12(3):e00380-21,lynnh@ku.edu,The ccpA mutation in the CAUTI model showed that the absence of carbon catabolite control significantly attenuated bacterial tissue burden in this model.,E C Keffeler 2021,2021,2 genes,Keffeler-2021-Influence of the Alternative Sig,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18296,PHI:11335,,no data found,,,,,,Pdr802,,,,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),,,,lung,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33981763,PubMed,10.15698/mic2021.05.750,Microb Cell. 2021 Apr 20;8(5):108-110,livia.kmetzsch@ufrgs.br,"Cryptococci lacking Pdr802 displayed enlarged capsules and enhanced Titan cell production, along with dramatically reduced virulence in a mouse model of infection.",J C V Reuwsaat 2021,2021,1 gene,Reuwsaat-2021-Too much of a good thing_ Overpr,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18297,PHI:11336,UniProt,I6Y4D2,GenBank,CCP46543,,,H37Rv,ami1 (Rv3717),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,N-acetylmuramyl-L-alanine amidases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33980132,PubMed,10.1080/21505594.2021.1914448,Virulence. 2021 Dec;12(1):1227-1238,reto.guler@uct.ac.za,Both Ami1 and Ami4 in M. tuberculosis were not essential for mycobacterial growth within the host.,N S Kieswetter 2021,2021,2 genes,Kieswetter-2021-Deletion of N-acetylmuramyl-L-,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18298,PHI:11337,UniProt,I6Y3Z2,GenBank,CCP46417,,,H37Rv,ami4 (Rv3594),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,N-acetylmuramyl-L-alanine amidases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33980132,PubMed,10.1080/21505594.2021.1914448,Virulence. 2021 Dec;12(1):1227-1238,reto.guler@uct.ac.za,Both Ami1 and Ami4 in M. tuberculosis were not essential for mycobacterial growth within the host.,N S Kieswetter 2021,2021,2 genes,Kieswetter-2021-Deletion of N-acetylmuramyl-L-,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18299,PHI:11336,UniProt,I6Y4D2,GenBank,CCP46543,,,H37Rv,ami1 (Rv3717),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,N-acetylmuramyl-L-alanine amidases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33980132,PubMed,10.1080/21505594.2021.1914448,Virulence. 2021 Dec;12(1):1227-1238,reto.guler@uct.ac.za,"Infection with the Δami1 mutant led to differential induction of pro-inflammatory cytokines and chemokines, decreased cellular recruitment and reduced lung pathology during the acute phase of the infection.",N S Kieswetter 2021,2021,2 genes,Kieswetter-2021-Deletion of N-acetylmuramyl-L-,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18300,PHI:11338,UniProt,O25656,GenBank,AAD08056,,,26695,PqqE (HP1012),,recombinant variants lacking the HMLEH motif (ΔHMLEH),,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS-Ecad cell line,,,gastric epithelial cell,protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; other evidence: recombinant protein,,,YVS,33970782,PubMed,10.1080/19490976.2021.1921928,Gut Microbes. 2021 Jan-Dec;13(1):1-21,cfigueiredo@ipatimup.pt,"While recombinant PqqE cleaved the JAM-A cytoplasmic peptide, recombinants with deletions or amino acid substitutions of the metal ligand-active site had almost completely abolished protease activity.",M S Marques 2021,2021,2 genes,Marques-2021-Helicobacter pylori PqqE is a new,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18301,PHI:11338,UniProt,O25656,GenBank,AAD08056,,,26695,PqqE (HP1012),,amnio acid substitutions in this motif (QMLQL),,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS-Ecad cell line,,,gastric epithelial cell,protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; other evidence: recombinant protein,,,YVS,33970782,PubMed,10.1080/19490976.2021.1921928,Gut Microbes. 2021 Jan-Dec;13(1):1-21,cfigueiredo@ipatimup.pt,"While recombinant PqqE cleaved the JAM-A cytoplasmic peptide, recombinants with deletions or amino acid substitutions of the metal ligand-active site had almost completely abolished protease activity.",M S Marques 2021,2021,2 genes,Marques-2021-Helicobacter pylori PqqE is a new,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18302,PHI:11338,UniProt,O25656,GenBank,AAD08056,,,26695,PqqE (HP1012),,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS-Ecad cell line,,,gastric epithelial cell,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,33970782,PubMed,10.1080/19490976.2021.1921928,Gut Microbes. 2021 Jan-Dec;13(1):1-21,cfigueiredo@ipatimup.pt,"While recombinant PqqE cleaved the JAM-A cytoplasmic peptide, recombinants with deletions or amino acid substitutions of the metal ligand-active site had almost completely abolished protease activity.",M S Marques 2021,2021,2 genes,Marques-2021-Helicobacter pylori PqqE is a new,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18303,PHI:11338,UniProt,O25656,GenBank,AAD08056,,,26695,PqqE (HP1012),,,,,,PHI:11339,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS-Ecad cell line,,,gastric epithelial cell,protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,33970782,PubMed,10.1080/19490976.2021.1921928,Gut Microbes. 2021 Jan-Dec;13(1):1-21,cfigueiredo@ipatimup.pt,"While recombinant PqqE cleaved the JAM-A cytoplasmic peptide, recombinants with deletions or amino acid substitutions of the metal ligand-active site had almost completely abolished protease activity.",M S Marques 2021,2021,2 genes,Marques-2021-Helicobacter pylori PqqE is a new,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18304,PHI:11339,UniProt,O25371,GenBank,AAD07722,,,26695,YmxG (HP0657),,,,,,PHI:11338,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS-Ecad cell line,,,gastric epithelial cell,processing protease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,33970782,PubMed,10.1080/19490976.2021.1921928,Gut Microbes. 2021 Jan-Dec;13(1):1-21,cfigueiredo@ipatimup.pt,"While recombinant PqqE cleaved the JAM-A cytoplasmic peptide, recombinants with deletions or amino acid substitutions of the metal ligand-active site had almost completely abolished protease activity.",M S Marques 2021,2021,2 genes,Marques-2021-Helicobacter pylori PqqE is a new,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18305,PHI:11339,UniProt,O25371,GenBank,AAD07722,,,26695,YmxG (HP0657),,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS-Ecad cell line,,,gastric epithelial cell,processing protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,33970782,PubMed,10.1080/19490976.2021.1921928,Gut Microbes. 2021 Jan-Dec;13(1):1-21,cfigueiredo@ipatimup.pt,"While recombinant PqqE cleaved the JAM-A cytoplasmic peptide, recombinants with deletions or amino acid substitutions of the metal ligand-active site had almost completely abolished protease activity.",M S Marques 2021,2021,2 genes,Marques-2021-Helicobacter pylori PqqE is a new,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18306,PHI:11339,UniProt,O25371,GenBank,AAD07722,,,26695,YmxG (HP0657),,ΔRY; lacking amino acids G285 to Y307,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS-Ecad cell line,,,gastric epithelial cell,processing protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; other evidence: recombinant protein,,,YVS,33970782,PubMed,10.1080/19490976.2021.1921928,Gut Microbes. 2021 Jan-Dec;13(1):1-21,cfigueiredo@ipatimup.pt,"While recombinant PqqE cleaved the JAM-A cytoplasmic peptide, recombinants with deletions or amino acid substitutions of the metal ligand-active site had almost completely abolished protease activity.",M S Marques 2021,2021,2 genes,Marques-2021-Helicobacter pylori PqqE is a new,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18307,PHI:11340,UniProt,J5J977,GenBank,EJP62838,,,ARSEF 2860,dim5,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,cuticle; hemocoel,SET domain protein,,,,loss of pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white; H2O2; menadione; sorbitol; NaCl,calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; menadione: CHEBI:28869; sorbitol: CHEBI:30911; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,33955325,PubMed,10.1080/21505594.2021.1923232,Virulence. 2021 Dec;12(1):1306-1322,tongsm@zafu.edu.cn,"The Δdim5 mutant lost the whole insect pathogenicity through normal cuticle infection, and was compromised severely in virulence through cuticle-bypassing infection (hemocoel injection)",K Ren 2021,2021,1 gene,Ren-2021-DIM5_KMT1 controls fungal insect path,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18308,PHI:11341,UniProt,A0A4P0MU30,GenBank,VTI81216,,,GPSC81,PspA,,,,,,,1313,Streptococcus pneumoniae,,WU2,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,pneumococcal surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33947761,PubMed,10.1128/mBio.00673-21,mBio. 2021 May 4;12(3):e00673-21,corihuel@uab.edu,Incubation of Spn carrying a version of PspA lacking the NPB with LDH-A or incubation of wild-type Spn with enzymatically inactiveLDH-A did not enhance virulence.,S S Park 2021,2021,1 gene,Park-2021-Streptococcus pneumoniae Binds to Ho,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18309,PHI:11341,UniProt,A0A4P0MU30,GenBank,VTI81216,,,GPSC81,PspA,,lacking a conserved 22-amino-acid nonproline block (NPB),,,,,1313,Streptococcus pneumoniae,,WU2,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,pneumococcal surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33947761,PubMed,10.1128/mBio.00673-21,mBio. 2021 May 4;12(3):e00673-21,corihuel@uab.edu,Incubation of Spn carrying a version of PspA lacking the NPB with LDH-A or incubation of wild-type Spn with enzymatically inactiveLDH-A did not enhance virulence.,S S Park 2021,2021,1 gene,Park-2021-Streptococcus pneumoniae Binds to Ho,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18310,PHI:11342,UniProt,Q4WGN2,GenBank,EAL86909,,,Af293,mbsA (Afu7g05620),chromosome 7,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,APSES family transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,nikkomycin Z,nikkomycin Z: CHEBI:623918,,,,,gene deletion: full; gene complementation,,,YVS,33917505,PubMed,10.3390/ijms22073777,Int J Mol Sci. 2021 Apr 6;22(7):3777,shinks@dju.kr,The deletion of mbsA resulted in significantly decreased hyphal growth and asexual sporulation (conidiation).,Y H Choi 2021,2021,1 gene,Choi-2021-Characterization of the mbsA Gene En,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18311,PHI:11343,UniProt,A0A0H2VAW4,GenBank,AE016755_285,,,CFT073,c2515,,,,,,,562,Escherichia coli,,E516,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,putative iron transport protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33912608,PubMed,10.3389/fvets.2021.654721,Front Vet Sci. 2021 Apr 12;8:654721,gsong@yzu.edu.cn,"Inactivation of the c2515 and c2516 genes affected bacterial colonization of chicken tissues, as well as the 50% lethal dose levels compared with the WT strain.",Q Gao 2021,2021,2 genes,Gao-2021-Deletion of the c2515 and c2516 Genes,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18312,PHI:11344,UniProt,A0A0H2V4D2,GenBank,AE016755_284,,,CFT073,c2516,,,,,,,562,Escherichia coli,,E516,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,putative iron transport protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33912608,PubMed,10.3389/fvets.2021.654721,Front Vet Sci. 2021 Apr 12;8:654721,gsong@yzu.edu.cn,"Inactivation of the c2515 and c2516 genes affected bacterial colonization of chicken tissues, as well as the 50% lethal dose levels compared with the WT strain.",Q Gao 2021,2021,2 genes,Gao-2021-Deletion of the c2515 and c2516 Genes,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18313,PHI:11343,UniProt,A0A0H2VAW4,GenBank,AE016755_285,,,CFT073,c2515,,,,,,PHI:11344,562,Escherichia coli,,E516,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,putative iron transport protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33912608,PubMed,10.3389/fvets.2021.654721,Front Vet Sci. 2021 Apr 12;8:654721,gsong@yzu.edu.cn,"Inactivation of the c2515 and c2516 genes affected bacterial colonization of chicken tissues, as well as the 50% lethal dose levels compared with the WT strain.",Q Gao 2021,2021,2 genes,Gao-2021-Deletion of the c2515 and c2516 Genes,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18314,PHI:11344,UniProt,A0A0H2V4D2,GenBank,AE016755_284,,,CFT073,c2516,,,,,,PHI:11343,562,Escherichia coli,,E516,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,putative iron transport protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33912608,PubMed,10.3389/fvets.2021.654721,Front Vet Sci. 2021 Apr 12;8:654721,gsong@yzu.edu.cn,"Inactivation of the c2515 and c2516 genes affected bacterial colonization of chicken tissues, as well as the 50% lethal dose levels compared with the WT strain.",Q Gao 2021,2021,2 genes,Gao-2021-Deletion of the c2515 and c2516 Genes,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18315,PHI:11343,UniProt,A0A0H2VAW4,GenBank,AE016755_285,,,CFT073,c2515,,,,,,,562,Escherichia coli,,E516,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,heart; liver; lung; spleen; kidney,putative iron transport protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33912608,PubMed,10.3389/fvets.2021.654721,Front Vet Sci. 2021 Apr 12;8:654721,gsong@yzu.edu.cn,"Inactivation of the c2515 and c2516 genes affected bacterial colonization of chicken tissues, as well as the 50% lethal dose levels compared with the WT strain.",Q Gao 2021,2021,2 genes,Gao-2021-Deletion of the c2515 and c2516 Genes,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18316,PHI:11344,UniProt,A0A0H2V4D2,GenBank,AE016755_284,,,CFT073,c2516,,,,,,,562,Escherichia coli,,E516,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,heart; liver; lung; spleen; kidney,putative iron transport protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33912608,PubMed,10.3389/fvets.2021.654721,Front Vet Sci. 2021 Apr 12;8:654721,gsong@yzu.edu.cn,"Inactivation of the c2515 and c2516 genes affected bacterial colonization of chicken tissues, as well as the 50% lethal dose levels compared with the WT strain.",Q Gao 2021,2021,2 genes,Gao-2021-Deletion of the c2515 and c2516 Genes,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18317,PHI:11343,UniProt,A0A0H2VAW4,GenBank,AE016755_285,,,CFT073,c2515,,,,,,PHI:11344,562,Escherichia coli,,E516,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,heart; liver; lung; spleen; kidney,putative iron transport protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33912608,PubMed,10.3389/fvets.2021.654721,Front Vet Sci. 2021 Apr 12;8:654721,gsong@yzu.edu.cn,"Inactivation of the c2515 and c2516 genes affected bacterial colonization of chicken tissues, as well as the 50% lethal dose levels compared with the WT strain.",Q Gao 2021,2021,2 genes,Gao-2021-Deletion of the c2515 and c2516 Genes,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18318,PHI:11344,UniProt,A0A0H2V4D2,GenBank,AE016755_284,,,CFT073,c2516,,,,,,PHI:11343,562,Escherichia coli,,E516,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,heart; liver; lung; spleen; kidney,putative iron transport protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33912608,PubMed,10.3389/fvets.2021.654721,Front Vet Sci. 2021 Apr 12;8:654721,gsong@yzu.edu.cn,"Inactivation of the c2515 and c2516 genes affected bacterial colonization of chicken tissues, as well as the 50% lethal dose levels compared with the WT strain.",Q Gao 2021,2021,2 genes,Gao-2021-Deletion of the c2515 and c2516 Genes,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18319,PHI:11345,UniProt,P10481,GenBank,CAA68780,,,A99,nanH,,,,,,,1502,Clostridium perfringens,,SM101,intestinal disease,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,sialidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33910991,PubMed,10.1128/mSphere.00176-21,mSphere. 2021 Apr 28;6(2):e00176-21,bamcc@pitt.edu,"The nanH null mutant, cpe null mutant and cpe nanH double null mutant caused significantly less cytotoxicity compared to the strain SM101.",J Li 2021,2021,2 genes,Li-2021-NanH Is Produced by Sporulating Cultur,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18320,PHI:11346,UniProt,P01558,GenBank,CAA50691,,,type A,cpe,,,,,,,1502,Clostridium perfringens,,SM101,intestinal disease,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,enterotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33910991,PubMed,10.1128/mSphere.00176-21,mSphere. 2021 Apr 28;6(2):e00176-21,bamcc@pitt.edu,"The nanH null mutant, cpe null mutant and cpe nanH double null mutant caused significantly less cytotoxicity compared to the strain SM101.",J Li 2021,2021,2 genes,Li-2021-NanH Is Produced by Sporulating Cultur,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18321,PHI:11345,UniProt,P10481,GenBank,CAA68780,,,A99,nanH,,,,,,PHI:11346,1502,Clostridium perfringens,,SM101,intestinal disease,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,sialidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33910991,PubMed,10.1128/mSphere.00176-21,mSphere. 2021 Apr 28;6(2):e00176-21,bamcc@pitt.edu,"The nanH null mutant, cpe null mutant and cpe nanH double null mutant caused significantly less cytotoxicity compared to the strain SM101.",J Li 2021,2021,2 genes,Li-2021-NanH Is Produced by Sporulating Cultur,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18322,PHI:11346,UniProt,P01558,GenBank,CAA50691,,,type A,cpe,,,,,,PHI:11345,1502,Clostridium perfringens,,SM101,intestinal disease,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,enterotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33910991,PubMed,10.1128/mSphere.00176-21,mSphere. 2021 Apr 28;6(2):e00176-21,bamcc@pitt.edu,"The nanH null mutant, cpe null mutant and cpe nanH double null mutant caused significantly less cytotoxicity compared to the strain SM101.",J Li 2021,2021,2 genes,Li-2021-NanH Is Produced by Sporulating Cultur,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18323,PHI:11347,UniProt,Q9HWQ1,GenBank,AE004829_7,,,PAO1,PA4130,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCrl,,,lung; liver; spleen,probable sulfite or nitrite reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33879591,PubMed,10.1128/mBio.00207-21,mBio. 2021 Apr 20;12(2):e00207-21,Miguel.Camara@nottingham.ac.uk,The PA4130 isogenic mutant showed substantial attenuation in disease models of Drosophila melanogaster and Caenorhabditis elegans as well as reduced toxicity in human cell lines.,S Fenn 2021,2021,1 gene,Fenn-2021-NirA Is an Alternative Nitrite Reduc,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18324,PHI:11347,UniProt,Q9HWQ1,GenBank,AE004829_7,,,PAO1,PA4130,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,probable sulfite or nitrite reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33879591,PubMed,10.1128/mBio.00207-21,mBio. 2021 Apr 20;12(2):e00207-21,Miguel.Camara@nottingham.ac.uk,The PA4130 isogenic mutant showed substantial attenuation in disease models of Drosophila melanogaster and Caenorhabditis elegans as well as reduced toxicity in human cell lines.,S Fenn 2021,2021,1 gene,Fenn-2021-NirA Is an Alternative Nitrite Reduc,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18325,PHI:11347,UniProt,Q9HWQ1,GenBank,AE004829_7,,,PAO1,PA4130,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,probable sulfite or nitrite reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33879591,PubMed,10.1128/mBio.00207-21,mBio. 2021 Apr 20;12(2):e00207-21,Miguel.Camara@nottingham.ac.uk,The PA4130 isogenic mutant showed substantial attenuation in disease models of Drosophila melanogaster and Caenorhabditis elegans as well as reduced toxicity in human cell lines.,S Fenn 2021,2021,1 gene,Fenn-2021-NirA Is an Alternative Nitrite Reduc,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18326,PHI:11347,UniProt,Q9HWQ1,GenBank,AE004829_7,,,PAO1,PA4130,,,,,,,287,Pseudomonas aeruginosa,,PAO1-L,infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,probable sulfite or nitrite reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33879591,PubMed,10.1128/mBio.00207-21,mBio. 2021 Apr 20;12(2):e00207-21,Miguel.Camara@nottingham.ac.uk,The PA4130 isogenic mutant showed substantial attenuation in disease models of Drosophila melanogaster and Caenorhabditis elegans as well as reduced toxicity in human cell lines.,S Fenn 2021,2021,1 gene,Fenn-2021-NirA Is an Alternative Nitrite Reduc,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18327,PHI:11348,UniProt,A0A2L1CGE9,GenBank,AVC43502,,,TCH2015,clpB,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33875476,PubMed,10.1128/IAI.00579-20,Infect Immun. 2021 Apr 19:IAI.00579-20,marek.basler@unibas.ch,"Even one of PdpC, PdpD or OpiA T6SS effectors was sufficient to kill G. mellonella larvae while sheath recycling by ClpB was dispensable.",M Brodmann 2021,2021,6 genes,Brodmann-2021-Type VI secretion system and its,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18328,PHI:11349,UniProt,Q7X3J1,GenBank,AAP58966,,,U112,pdpC,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33875476,PubMed,10.1128/IAI.00579-20,Infect Immun. 2021 Apr 19:IAI.00579-20,marek.basler@unibas.ch,"Even one of PdpC, PdpD or OpiA T6SS effectors was sufficient to kill G. mellonella larvae while sheath recycling by ClpB was dispensable.",M Brodmann 2021,2021,6 genes,Brodmann-2021-Type VI secretion system and its,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18329,PHI:11350,UniProt,Q7X3J6,GenBank,AAP58961,,,U112,pdpD,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33875476,PubMed,10.1128/IAI.00579-20,Infect Immun. 2021 Apr 19:IAI.00579-20,marek.basler@unibas.ch,"Even one of PdpC, PdpD or OpiA T6SS effectors was sufficient to kill G. mellonella larvae while sheath recycling by ClpB was dispensable.",M Brodmann 2021,2021,6 genes,Brodmann-2021-Type VI secretion system and its,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18330,PHI:11349,UniProt,Q7X3J1,GenBank,AAP58966,,,U112,pdpC,,,,,,PHI:11350,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33875476,PubMed,10.1128/IAI.00579-20,Infect Immun. 2021 Apr 19:IAI.00579-20,marek.basler@unibas.ch,"Even one of PdpC, PdpD or OpiA T6SS effectors was sufficient to kill G. mellonella larvae while sheath recycling by ClpB was dispensable.",M Brodmann 2021,2021,6 genes,Brodmann-2021-Type VI secretion system and its,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18331,PHI:11350,UniProt,Q7X3J6,GenBank,AAP58961,,,U112,pdpD,,,,,,PHI:11349,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33875476,PubMed,10.1128/IAI.00579-20,Infect Immun. 2021 Apr 19:IAI.00579-20,marek.basler@unibas.ch,"Even one of PdpC, PdpD or OpiA T6SS effectors was sufficient to kill G. mellonella larvae while sheath recycling by ClpB was dispensable.",M Brodmann 2021,2021,6 genes,Brodmann-2021-Type VI secretion system and its,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18332,PHI:11351,,no data found,,,,,,opiA,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33875476,PubMed,10.1128/IAI.00579-20,Infect Immun. 2021 Apr 19:IAI.00579-20,marek.basler@unibas.ch,"Even one of PdpC, PdpD or OpiA T6SS effectors was sufficient to kill G. mellonella larvae while sheath recycling by ClpB was dispensable.",M Brodmann 2021,2021,6 genes,Brodmann-2021-Type VI secretion system and its,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18333,PHI:11352,UniProt,A0A2L1CHL6,GenBank,AVC43900,,,TCH2015,anmK,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33875476,PubMed,10.1128/IAI.00579-20,Infect Immun. 2021 Apr 19:IAI.00579-20,marek.basler@unibas.ch,"Even one of PdpC, PdpD or OpiA T6SS effectors was sufficient to kill G. mellonella larvae while sheath recycling by ClpB was dispensable.",M Brodmann 2021,2021,6 genes,Brodmann-2021-Type VI secretion system and its,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18334,PHI:11353,,no data found,,,,,,opiB1-3,,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33875476,PubMed,10.1128/IAI.00579-20,Infect Immun. 2021 Apr 19:IAI.00579-20,marek.basler@unibas.ch,"Even one of PdpC, PdpD or OpiA T6SS effectors was sufficient to kill G. mellonella larvae while sheath recycling by ClpB was dispensable.",M Brodmann 2021,2021,6 genes,Brodmann-2021-Type VI secretion system and its,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18335,PHI:11354,UniProt,A0A1D8PPD8,GenBank,AOW29994,,,SC5314,fet3,chromosome 6,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,ferroxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33862618,PubMed,10.1093/mmy/myab015,Med Mycol. 2021 Apr 16:myab015,PohlCH@ufs.ac.za,"URA3 positive mutants of FET99 and FTH2 demonstrated attenuated virulence in C. elegans, potentially due to the inability of mutants to form hyphae in vivo.",B M Mochochoko 2021,2021,4 genes,Mochochoko-2021-Role of the high-affinity redu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18336,PHI:11355,UniProt,Q5AG51,GenBank,AOW29722,,,SC5314,ccc2,chromosome 5,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,Cu(2+)-transporting P-type ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33862618,PubMed,10.1093/mmy/myab015,Med Mycol. 2021 Apr 16:myab015,PohlCH@ufs.ac.za,"URA3 positive mutants of FET99 and FTH2 demonstrated attenuated virulence in C. elegans, potentially due to the inability of mutants to form hyphae in vivo.",B M Mochochoko 2021,2021,4 genes,Mochochoko-2021-Role of the high-affinity redu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18337,PHI:11356,UniProt,A0A1D8PRX4,GenBank,AOW30888,,,SC5314,fth2,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,iron permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33862618,PubMed,10.1093/mmy/myab015,Med Mycol. 2021 Apr 16:myab015,PohlCH@ufs.ac.za,"URA3 positive mutants of FET99 and FTH2 demonstrated attenuated virulence in C. elegans, potentially due to the inability of mutants to form hyphae in vivo.",B M Mochochoko 2021,2021,4 genes,Mochochoko-2021-Role of the high-affinity redu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18338,PHI:11357,UniProt,A0A1D8PPE6,GenBank,AOW29995,,,SC5314,fet99,chromosome 6,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,multicopper oxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33862618,PubMed,10.1093/mmy/myab015,Med Mycol. 2021 Apr 16:myab015,PohlCH@ufs.ac.za,"URA3 positive mutants of FET99 and FTH2 demonstrated attenuated virulence in C. elegans, potentially due to the inability of mutants to form hyphae in vivo.",B M Mochochoko 2021,2021,4 genes,Mochochoko-2021-Role of the high-affinity redu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18339,PHI:11354,UniProt,A0A1D8PPD8,GenBank,AOW29994,,,SC5314,fet3,chromosome 6,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,ferroxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33862618,PubMed,10.1093/mmy/myab015,Med Mycol. 2021 Apr 16:myab015,PohlCH@ufs.ac.za,"URA3 positive mutants of FET99 and FTH2 demonstrated attenuated virulence in C. elegans, potentially due to the inability of mutants to form hyphae in vivo.",B M Mochochoko 2021,2021,4 genes,Mochochoko-2021-Role of the high-affinity redu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18340,PHI:11355,UniProt,Q5AG51,GenBank,AOW29722,,,SC5314,ccc2,chromosome 5,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,Cu(2+)-transporting P-type ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33862618,PubMed,10.1093/mmy/myab015,Med Mycol. 2021 Apr 16:myab015,PohlCH@ufs.ac.za,"URA3 positive mutants of FET99 and FTH2 demonstrated attenuated virulence in C. elegans, potentially due to the inability of mutants to form hyphae in vivo.",B M Mochochoko 2021,2021,4 genes,Mochochoko-2021-Role of the high-affinity redu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18341,PHI:11356,UniProt,A0A1D8PRX4,GenBank,AOW30888,,,SC5314,fth2,chromosome R,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,iron permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33862618,PubMed,10.1093/mmy/myab015,Med Mycol. 2021 Apr 16:myab015,PohlCH@ufs.ac.za,"URA3 positive mutants of FET99 and FTH2 demonstrated attenuated virulence in C. elegans, potentially due to the inability of mutants to form hyphae in vivo.",B M Mochochoko 2021,2021,4 genes,Mochochoko-2021-Role of the high-affinity redu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18342,PHI:11357,UniProt,A0A1D8PPE6,GenBank,AOW29995,,,SC5314,fet99,chromosome 6,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,multicopper oxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33862618,PubMed,10.1093/mmy/myab015,Med Mycol. 2021 Apr 16:myab015,PohlCH@ufs.ac.za,"URA3 positive mutants of FET99 and FTH2 demonstrated attenuated virulence in C. elegans, potentially due to the inability of mutants to form hyphae in vivo.",B M Mochochoko 2021,2021,4 genes,Mochochoko-2021-Role of the high-affinity redu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18343,PHI:11358,UniProt,A0A384J6C4,GenBank,ATZ45904,,,B05.10,crh1 (Bcin01g06010),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),N9059,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33846308,PubMed,10.1038/s41467-021-22436-1,Nat Commun. 2021 Apr 12;12(1):2166,amirsh@tauex.tau.ac.il,A stretch of 35 amino acids of BcCrh1 was necessary and sufficient for the induction of plant cell death.,K Bi 2021,2021,1 gene,Bi-2021-The Botrytis cinerea Crh1 transglycosy,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18344,PHI:11358,UniProt,A0A384J6C4,GenBank,ATZ45904,,,B05.10,crh1 (Bcin01g06010),chromosome BCIN01,mutation of the conserved residues (MBcCrh1:E120Q/D122H/E124Q) at the putative catalytic site,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),N9059,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,33846308,PubMed,10.1038/s41467-021-22436-1,Nat Commun. 2021 Apr 12;12(1):2166,amirsh@tauex.tau.ac.il,Over expression of MBcCrh1 causes reduced pathogenicity and developmental defects.,K Bi 2021,2021,1 gene,Bi-2021-The Botrytis cinerea Crh1 transglycosy,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18345,PHI:11358,UniProt,A0A384J6C4,GenBank,ATZ45904,,,B05.10,crh1 (Bcin01g06010),chromosome BCIN01,"mutation of the conserved residues (MBcCrh1:E120Q/D122H/E124Q) at the putative catalytic site and C26A, C33A",,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),N9059,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; altered gene expression / gene regulation: overexpression,,,YVS,33846308,PubMed,10.1038/s41467-021-22436-1,Nat Commun. 2021 Apr 12;12(1):2166,amirsh@tauex.tau.ac.il,"MBcCrh1C26AC33A, which was unable to form dimers, in a Δbccrh1 background had no growth defects, and it caused normal disease symptoms.",K Bi 2021,2021,1 gene,Bi-2021-The Botrytis cinerea Crh1 transglycosy,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18346,PHI:11358,UniProt,A0A384J6C4,GenBank,ATZ45904,,,B05.10,crh1 (Bcin01g06010),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,33846308,PubMed,10.1038/s41467-021-22436-1,Nat Commun. 2021 Apr 12;12(1):2166,amirsh@tauex.tau.ac.il,Arabidopsis lines expressing the bccrh1 gene exhibited reduced sensitivity to B. cinerea.,K Bi 2021,2021,1 gene,Bi-2021-The Botrytis cinerea Crh1 transglycosy,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18347,PHI:11359,UniProt,C0RJX3,GenBank,ACO01906,,,ATCC 23457,B0022 (BcrS),chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,extracytoplasmic function (ECF) sigma factor,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; HOCl,H2O2: CHEBI:16240; HOCl: CHEBI:24757,,,,,gene deletion: full; gene complementation,,,YVS,33820796,PubMed,10.1128/JB.00127-21,J Bacteriol. 2021 Apr 5:JB.00127-21,caiwentong@caas.cn,"AbcS was required for the maintenance of persistent infection, while bcrS was dispensable in a mouse infection model.",H Li 2021,2021,5 genes,Li-2021-An extracytoplasmic function (ECF) sig,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18348,PHI:11360,UniProt,C0RJX2,GenBank,ACO01905,,,ATCC 23457,B0021 (bcrX),chromosome II,,,,,PHI:11361; PHI:11362,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,putative methionine sulfoxide reductase system,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; HOCl,H2O2: CHEBI:16240; HOCl: CHEBI:24757,,,,,gene deletion: full; gene complementation,,,YVS,33820796,PubMed,10.1128/JB.00127-21,J Bacteriol. 2021 Apr 5:JB.00127-21,caiwentong@caas.cn,"AbcS was required for the maintenance of persistent infection, while bcrS was dispensable in a mouse infection model.",H Li 2021,2021,5 genes,Li-2021-An extracytoplasmic function (ECF) sig,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18349,PHI:11361,UniProt,C0RJX1,GenBank,ACO01904,,,ATCC 23457,B0020 (bcrQ),chromosome II,,,,,PHI:11360; PHI:11362,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,putative methionine sulfoxide reductase system,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; HOCl,H2O2: CHEBI:16240; HOCl: CHEBI:24757,,,,,gene deletion: full; gene complementation,,,YVS,33820796,PubMed,10.1128/JB.00127-21,J Bacteriol. 2021 Apr 5:JB.00127-21,caiwentong@caas.cn,"AbcS was required for the maintenance of persistent infection, while bcrS was dispensable in a mouse infection model.",H Li 2021,2021,5 genes,Li-2021-An extracytoplasmic function (ECF) sig,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18350,PHI:11362,UniProt,C0RJX0,GenBank,ACO01903,,,ATCC 23457,B0019 (bcrP),chromosome II,,,,,PHI:11360; PHI:11361,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,putative methionine sulfoxide reductase system,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; HOCl,H2O2: CHEBI:16240; HOCl: CHEBI:24757,,,,,gene deletion: full; gene complementation,,,YVS,33820796,PubMed,10.1128/JB.00127-21,J Bacteriol. 2021 Apr 5:JB.00127-21,caiwentong@caas.cn,"AbcS was required for the maintenance of persistent infection, while bcrS was dispensable in a mouse infection model.",H Li 2021,2021,5 genes,Li-2021-An extracytoplasmic function (ECF) sig,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18351,PHI:11363,UniProt,C0RJX4,GenBank,ACO01906,,,ATCC 23457,B0023 (abcS),chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,cognate anti-sigma factor,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; HOCl,H2O2: CHEBI:16240; HOCl: CHEBI:24757,,,,,gene deletion: full; gene complementation,,,YVS,33820796,PubMed,10.1128/JB.00127-21,J Bacteriol. 2021 Apr 5:JB.00127-21,caiwentong@caas.cn,"AbcS was required for the maintenance of persistent infection, while bcrS was dispensable in a mouse infection model.",H Li 2021,2021,5 genes,Li-2021-An extracytoplasmic function (ECF) sig,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18352,PHI:11364,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,,,,,,470,Acinetobacter baumannii,,Ab169,pneumonia,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33807410,PubMed,10.3390/pathogens10040407,Pathogens. 2021 Mar 31;10(4):407,skerniskyte@unistra.fr,OmpA protein present in A. baumannii OMVs substantially contributes to the proin?ammatory response in J774 murine macrophages and to the cell death in both lung epithelium cells and macrophages.,J Skerniskyte 2021,2021,1 gene,Skerniskyte-2021-OmpA Protein-Deficient Acinet,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18353,PHI:11364,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,,,,,,470,Acinetobacter baumannii,,Ab169,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33807410,PubMed,10.3390/pathogens10040407,Pathogens. 2021 Mar 31;10(4):407,skerniskyte@unistra.fr,OmpA protein present in A. baumannii OMVs substantially contributes to the proin?ammatory response in J774 murine macrophages and to the cell death in both lung epithelium cells and macrophages.,J Skerniskyte 2021,2021,1 gene,Skerniskyte-2021-OmpA Protein-Deficient Acinet,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18354,PHI:11365,UniProt,B1MD40,GenBank,CAM63161,,,ATCC 19977,Mab_3083c,,Mab_3083c::Tn Mutant,,,,,36809,Mycobacteroides abscessus,,cs1c-R,pulmonary infection; cutaneo-mucous infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,ribonuclease J,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation; gene complementation,,,YVS,33805851,PubMed,10.3390/microorganisms9040676,Microorganisms. 2021 Mar 25;9(4):676,yychen@mail.ncyu.edu.tw,The mutant was found to have a lower aggregative ability and a higher sliding motility than the wild type strain.,T Y Liu 2021,2021,1 gene,Liu-2021-Mab_3083c Is a Homologue of RNase J a,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18355,PHI:11366,UniProt,A0A2H1GTW7,GenBank,ZtritIPO323_04g12740,,,,Mgx1LysM,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18356,PHI:11367,UniProt,F9XHX3,Ensembl Genomes,Mycgr3g105487,,,,Mg1LysM,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18357,PHI:11368,UniProt,F9XMT4,Ensembl Genomes,Mycgr3G111221,,,,Mg3LysM,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18358,PHI:11367,UniProt,F9XHX3,Ensembl Genomes,Mycgr3g105487,,,,Mg1LysM,,,,,,PHI:11366,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18359,PHI:11366,UniProt,A0A2H1GTW7,GenBank,ZtritIPO323_04g12740,,,,Mgx1LysM,,,,,,PHI:11367,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18360,PHI:11366,UniProt,A0A2H1GTW7,GenBank,ZtritIPO323_04g12740,,,,Mgx1LysM,,,,,,PHI:11368,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18361,PHI:11368,UniProt,F9XMT4,Ensembl Genomes,Mycgr3G111221,,,,Mg3LysM,,,,,,PHI:11366,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18362,PHI:11367,UniProt,F9XHX3,Ensembl Genomes,Mycgr3g105487,,,,Mg1LysM,,,,,,PHI:11366; PHI:11368,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18363,PHI:11366,UniProt,A0A2H1GTW7,GenBank,ZtritIPO323_04g12740,,,,Mgx1LysM,,,,,,PHI:11367; PHI:11368,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18364,PHI:11368,UniProt,F9XMT4,Ensembl Genomes,Mycgr3G111221,,,,Mg3LysM,,,,,,PHI:11367; PHI:11366,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18365,PHI:11367,UniProt,F9XHX3,Ensembl Genomes,Mycgr3g105487,,,,Mg1LysM,,,,,,PHI:11368,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18366,PHI:11368,UniProt,F9XMT4,Ensembl Genomes,Mycgr3G111221,,,,Mg3LysM,,,,,,PHI:11367,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33797163,PubMed,10.1111/mpp.13055,Mol Plant Pathol. 2021 Jun;22(6):683-693,bthomma@uni-koeln.de,"While Mg3LysM confered a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contributed to Z. tritici virulence with smaller effects.",H Tian 2021,2021,3 genes,Tian-2021-Three LysM effectors of Zymoseptoria,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18367,PHI:11369,UniProt,Q4WX78,GenBank,EAL92725,,,Af293,rlmA (Afu3g08520),chromosome 3,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,SRF-type transcription factor,,,,reduced virulence,,,,,,,,,,no,SDS; caspofungin; congo red; calcofluor white; H2O2,SDS: CHEBI:8984; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33780518,PubMed,10.1371/journal.ppat.1009235,PLoS Pathog. 2021 Mar 29;17(3):e1009235,sfiller@ucla.edu,Two transcription factor genes rlmA and sltA were found to be required for maximal virulence.,H Liu 2021,2021,4 genes,Liu-2021-Determining Aspergillus fumigatus tra,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18368,PHI:11370,UniProt,Q4WX28,GenBank,EAL92775,,,Af293,sltA (Afu3g08010),chromosome 3,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,C2H2 transcription factor,,,,reduced virulence,,,,,,,,,,no,SDS; caspofungin; congo red; calcofluor white; H2O2,SDS: CHEBI:8984; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,33780518,PubMed,10.1371/journal.ppat.1009235,PLoS Pathog. 2021 Mar 29;17(3):e1009235,sfiller@ucla.edu,Two transcription factor genes rlmA and sltA were found to be required for maximal virulence.,H Liu 2021,2021,4 genes,Liu-2021-Determining Aspergillus fumigatus tra,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18369,PHI:11371,UniProt,Q50EL0,GenBank,AAX08549,,,Af293,dmaW (Afu2g18040),,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,tryptophan dimethylallyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; caspofungin; congo red; calcofluor white; H2O2,SDS: CHEBI:8984; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full,,,YVS,33780518,PubMed,10.1371/journal.ppat.1009235,PLoS Pathog. 2021 Mar 29;17(3):e1009235,sfiller@ucla.edu,Two transcription factor genes rlmA and sltA were found to be required for maximal virulence.,H Liu 2021,2021,4 genes,Liu-2021-Determining Aspergillus fumigatus tra,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18370,PHI:11372,UniProt,Q4WAY8,GenBank,EAL85124,,,Af293,fumR (Afu8g00420),chromosome 8,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,C6 finger transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; caspofungin; congo red; calcofluor white; H2O2,SDS: CHEBI:8984; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full,,,YVS,33780518,PubMed,10.1371/journal.ppat.1009235,PLoS Pathog. 2021 Mar 29;17(3):e1009235,sfiller@ucla.edu,Two transcription factor genes rlmA and sltA were found to be required for maximal virulence.,H Liu 2021,2021,4 genes,Liu-2021-Determining Aspergillus fumigatus tra,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18371,PHI:11371,UniProt,Q50EL0,GenBank,AAX08549,,,Af293,dmaW (Afu2g18040),,,,,,PHI:11372,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,tryptophan dimethylallyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; caspofungin; congo red; calcofluor white; H2O2,SDS: CHEBI:8984; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full,,,YVS,33780518,PubMed,10.1371/journal.ppat.1009235,PLoS Pathog. 2021 Mar 29;17(3):e1009235,sfiller@ucla.edu,Two transcription factor genes rlmA and sltA were found to be required for maximal virulence.,H Liu 2021,2021,4 genes,Liu-2021-Determining Aspergillus fumigatus tra,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18372,PHI:11372,UniProt,Q4WAY8,GenBank,EAL85124,,,Af293,fumR (Afu8g00420),chromosome 8,,,,,PHI:11371,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,C6 finger transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; caspofungin; congo red; calcofluor white; H2O2,SDS: CHEBI:8984; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full,,,YVS,33780518,PubMed,10.1371/journal.ppat.1009235,PLoS Pathog. 2021 Mar 29;17(3):e1009235,sfiller@ucla.edu,Two transcription factor genes rlmA and sltA were found to be required for maximal virulence.,H Liu 2021,2021,4 genes,Liu-2021-Determining Aspergillus fumigatus tra,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18373,PHI:11373,UniProt,A0A411PX52,GenBank,QBG49687,,,BpShHep31,pirB,,,,,,,670,Vibrio parahaemolyticus,,,vibriosis,crustaceans,6689,Penaeus vannamei (related: Pacific white shrimp),,,,stomach; hepatopancreas; hemocyte,toxin protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,33770150,PubMed,10.1371/journal.ppat.1009463,PLoS Pathog. 2021 Mar 26;17(3):e1009463,kunlaya.s@chula.ac.th,"Host gene alteration data available for APN1. The rLvAPN1 directly bound to both rPirAVP and rPirBVP toxins, supporting the notion that silencing of LvAPN1 prevented the VPAHPND toxin from passing through the cell membrane of hemocytes.",W Luangtrakul 2021,2021,2 genes,Luangtrakul-2021-Cytotoxicity of Vibrio paraha,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18374,PHI:11374,UniProt,A0A411HE34,GenBank,AKC05671,,,3HP,PirA,,,,,,,670,Vibrio parahaemolyticus,,,vibriosis,crustaceans,6689,Penaeus vannamei (related: Pacific white shrimp),,,,stomach; hepatopancreas; hemocyte,toxin protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,33770150,PubMed,10.1371/journal.ppat.1009463,PLoS Pathog. 2021 Mar 26;17(3):e1009463,kunlaya.s@chula.ac.th,"Host gene alteration data available for APN1. The rLvAPN1 directly bound to both rPirAVP and rPirBVP toxins, supporting the notion that silencing of LvAPN1 prevented the VPAHPND toxin from passing through the cell membrane of hemocytes.",W Luangtrakul 2021,2021,2 genes,Luangtrakul-2021-Cytotoxicity of Vibrio paraha,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18375,PHI:11375,UniProt,Q30H47,GenBank,KJE03598,,,NT-10,HOG1,,,,,,,552467,Cryptococcus bacillisporus,,CZ2012,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,high-osmolarity glycerol 1,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33767771,PubMed,10.3892/etm.2021.9907,Exp Ther Med. 2021 May;21(5):476,frankgets@sina.com,C. gattii hog1Δ strains (deletion of HOG1) also displayed decreased capsule production and melanin synthesis. pathogen species name changed in PHI4.17 from 'Cryptococcus gattii VGIII' to 'Cryptococcus bacillisporus'.,Y M Huang 2021,2021,1 gene,Huang-2021-HOG1 has an essential role in the s,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18376,PHI:11376,UniProt,P43019,GenBank,AAC43331,,,ATCC 14028,sodA,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,cytoplasmic superoxide dismutase,,,,reduced virulence,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18377,PHI:11377,UniProt,P0A2F4,GenBank,AAL20353,,,LT2,sodB,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,cytoplasmic superoxide dismutase,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18378,PHI:11376,UniProt,P43019,GenBank,AAC43331,,,ATCC 14028,sodA,,,,,,PHI:11377,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,cytoplasmic superoxide dismutase,,,,reduced virulence,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18379,PHI:11377,UniProt,P0A2F4,GenBank,AAL20353,,,LT2,sodB,,,,,,PHI:11376,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,cytoplasmic superoxide dismutase,,,,reduced virulence,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18380,PHI:11378,UniProt,P0CW86,GenBank,AAB62385,,,,sodCI,,,,,,PHI:11379,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,periplasmic superoxide dismutase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18381,PHI:11379,UniProt,O68901,GenBank,AAC13559,,,14028s,sodCII,,,,,,PHI:11378,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,periplasmic superoxide dismutase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18382,PHI:11380,UniProt,H9L460,GenBank,AAL20243,,,LT2,katE,,,,,,PHI:11381; PHI:11382,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,catalase,,,,reduced virulence,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18383,PHI:11381,UniProt,P17750,GenBank,AAL22946,,,LT2,katG,,,,,,PHI:11380; PHI:11382,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,catalase,,,,reduced virulence,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18384,PHI:11382,UniProt,A0A0H3NBW6,GenBank,CBW17757,,,SL1344,katN,,,,,,PHI:11380; PHI:11381,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,catalase,,,,reduced virulence,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18385,PHI:11383,UniProt,P0A251,GenBank,AAL19559,,,LT2,ahpC,,,,,,PHI:11384,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,peroxiredoxin,,,,reduced virulence,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18386,PHI:11384,UniProt,A0A0H3NDI1,GenBank,CBW16497,,,SL1344,tsaA,,,,,,PHI:11383,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,peroxiredoxin,,,,reduced virulence,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18387,PHI:11385,UniProt,Q7CPB9,GenBank,AAL22963,,,LT2,oxyR,,,,,,PHI:11383,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,regulatory protein sensor for oxidative stress,,,,reduced virulence,,,,,,,,,,no,H2O2; HOCl; paraquat,H2O2: CHEBI:16240; HOCl: CHEBI:24757; paraquat: CHEBI:34905,,,,,gene deletion: full,,,YVS,33732665,PubMed,10.3389/fcimb.2021.640112,Front Cell Infect Microbiol. 2021 Mar 1;11:640112,aussel@imm.cnrs.fr,"ROS production by G. mellonella was revealed by the virulence defects of Salmonella mutants lacking catalases/peroxiredoxins or cytoplasmic superoxide dismutases, both strains being highly sensitive to these oxidants.",H D Bismuth 2021,2021,10 genes,Bismuth-2021-Bacterial Genetic Approach to the,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18388,PHI:11386,UniProt,Q59L12,GenBank,AAO72959,,,SC5314,als3,chromosome R,,,,,,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18389,PHI:11387,UniProt,Q5AAL9,GenBank,AOW30829,,,SC5314,iff4,chromosome R,,,,,,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cell wall protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18390,PHI:11388,UniProt,A0A1D8PQ86,GenBank,AOW30298,,,SC5314,als9,chromosome 6,,,,,,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18391,PHI:11387,UniProt,Q5AAL9,GenBank,AOW30829,,,SC5314,iff4,chromosome R,,,,,,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cell wall protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18392,PHI:11389,UniProt,Q59PF9,GenBank,AOW29109,,,SC5314,hwp2,chromosome 4,,,,,,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,hyphal wall protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18393,PHI:11386,UniProt,Q59L12,GenBank,AAO72959,,,SC5314,als3,chromosome R,,,,,PHI:11389,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18394,PHI:11389,UniProt,Q59PF9,GenBank,AOW29109,,,SC5314,hwp2,chromosome 4,,,,,PHI:11386,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,hyphal wall protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18395,PHI:11388,UniProt,A0A1D8PQ86,GenBank,AOW30298,,,SC5314,als9,chromosome 6,,,,,PHI:11390,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18396,PHI:11390,UniProt,G1UBC2,GenBank,AOW27933,,,SC5314,eap1,chromosome 2,,,,,PHI:11388,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cell wall adhesin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18397,PHI:11391,UniProt,Q5AL03,GenBank,AOW26950,,,SC5314,hyr1,chromosome 1,,,,,PHI:11392,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,hyphally regulated cell wall protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18398,PHI:11392,UniProt,Q5A8T4,GenBank,AOW30297,,,SC5314,als1,chromosome 6,,,,,PHI:11391,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18399,PHI:11393,UniProt,Q5A312,GenBank,AOW28639,,,SC5314,als7,chromosome 3,,,,,PHI:11394,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18400,PHI:11394,UniProt,Q5A8T7,GenBank,AAO72528,,,SC5314,als5,chromosome 6,,,,,PHI:11393,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18401,PHI:11392,UniProt,Q5A8T4,GenBank,AOW30297,,,SC5314,als1,chromosome 6,,,,,PHI:11387,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18402,PHI:11387,UniProt,Q5AAL9,GenBank,AOW30829,,,SC5314,iff4,chromosome R,,,,,PHI:11392,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cell wall protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18403,PHI:11395,UniProt,Q5A6M0,GenBank,AOW31180,,,SC5314,rbr1,chromosome R,,,,,PHI:11392,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,repressed by RIM101 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18404,PHI:11392,UniProt,Q5A8T4,GenBank,AOW30297,,,SC5314,als1,chromosome 6,,,,,PHI:11395,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18405,PHI:11394,UniProt,Q5A8T7,GenBank,AAO72528,,,SC5314,als5,chromosome 6,,,,,,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18406,PHI:11390,UniProt,G1UBC2,GenBank,AOW27933,,,SC5314,eap1,chromosome 2,,,,,,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cell wall adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18407,PHI:11394,UniProt,Q5A8T7,GenBank,AAO72528,,,SC5314,als5,chromosome 6,,,,,PHI:11390,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18408,PHI:11390,UniProt,G1UBC2,GenBank,AOW27933,,,SC5314,eap1,chromosome 2,,,,,PHI:11394,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cell wall adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18409,PHI:11394,UniProt,Q5A8T7,GenBank,AAO72528,,,SC5314,als5,chromosome 6,,,,,PHI:11389,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,agglutinin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18410,PHI:11389,UniProt,Q59PF9,GenBank,AOW29109,,,SC5314,hwp2,chromosome 4,,,,,PHI:11394,5476,Candida albicans,,,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,hyphal wall protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33724419,PubMed,10.1093/genetics/iyab003,Genetics. 2021 Feb 9;217(2):iyab003,kirienko@rice.edu,"The three most significantly attenuated strains were hyr1Δals1Δ, als7Δals5Δ, and als1Δiff4Δ.",S Rosiana 2021,2021,10 genes,Rosiana-2021-Comprehensive genetic analysis of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18411,PHI:11396,,no data found,,,,,,ryhB1,,,,,,,28901,Salmonella enterica,,serovar Enteritidis strain CMCC(B)50336,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,"small non-coding RNA, regulator of iron homeostasis",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33691799,PubMed,10.1186/s13567-021-00915-z,Vet Res. 2021 Mar 10;52(1):44,mengxia_1@126.com,The deletion of RyhB-1 and/or RyhB-2 weakened the invasion ability of S. Enteritidis.,B Chen 2021,2021,2 genes,Chen-2021-Positive regulation of Type III secr,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18412,PHI:11397,,no data found,,,,,,ryhB2,,,,,,,28901,Salmonella enterica,,serovar Enteritidis strain CMCC(B)50336,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,"small non-coding RNA, regulator of iron homeostasis",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33691799,PubMed,10.1186/s13567-021-00915-z,Vet Res. 2021 Mar 10;52(1):44,mengxia_1@126.com,The deletion of RyhB-1 and/or RyhB-2 weakened the invasion ability of S. Enteritidis.,B Chen 2021,2021,2 genes,Chen-2021-Positive regulation of Type III secr,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18413,PHI:11396,,no data found,,,,,,ryhB1,,,,,,PHI:11397,28901,Salmonella enterica,,serovar Enteritidis strain CMCC(B)50336,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,"small non-coding RNA, regulator of iron homeostasis",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33691799,PubMed,10.1186/s13567-021-00915-z,Vet Res. 2021 Mar 10;52(1):44,mengxia_1@126.com,The deletion of RyhB-1 and/or RyhB-2 weakened the invasion ability of S. Enteritidis.,B Chen 2021,2021,2 genes,Chen-2021-Positive regulation of Type III secr,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18414,PHI:11397,,no data found,,,,,,ryhB2,,,,,,PHI:11396,28901,Salmonella enterica,,serovar Enteritidis strain CMCC(B)50336,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colon epithelial cell,"small non-coding RNA, regulator of iron homeostasis",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33691799,PubMed,10.1186/s13567-021-00915-z,Vet Res. 2021 Mar 10;52(1):44,mengxia_1@126.com,The deletion of RyhB-1 and/or RyhB-2 weakened the invasion ability of S. Enteritidis.,B Chen 2021,2021,2 genes,Chen-2021-Positive regulation of Type III secr,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18415,PHI:11398,,no data found,,,,,,siaF,,,,,,,1314,Streptococcus pyogenes,,serotype M49 strain NZ131,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,vaginal mucosa,heme transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32393520,PubMed,10.1128/JB.00205-20,J Bacteriol. 2020 Jun 25;202(14):e00205-20,zeichen@gsu.edu,The siaFGH mutant exhibited a significant impairment in murine models of mucosal colonization and systemic infection.,N Chatterjee 2020,2020,3 genes,Chatterjee-2020-A novel heme transporter from,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18416,PHI:11399,,no data found,,,,,,siaG,,,,,,,1314,Streptococcus pyogenes,,serotype M49 strain NZ131,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,vaginal mucosa,heme transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32393520,PubMed,10.1128/JB.00205-20,J Bacteriol. 2020 Jun 25;202(14):e00205-20,zeichen@gsu.edu,The siaFGH mutant exhibited a significant impairment in murine models of mucosal colonization and systemic infection.,N Chatterjee 2020,2020,3 genes,Chatterjee-2020-A novel heme transporter from,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18417,PHI:11400,,no data found,,,,,,siaH,,,,,,,1314,Streptococcus pyogenes,,serotype M49 strain NZ131,skin lesion,rodents,10090,Mus musculus (related: house mouse),CD-1,,,vaginal mucosa,heme transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32393520,PubMed,10.1128/JB.00205-20,J Bacteriol. 2020 Jun 25;202(14):e00205-20,zeichen@gsu.edu,The siaFGH mutant exhibited a significant impairment in murine models of mucosal colonization and systemic infection.,N Chatterjee 2020,2020,3 genes,Chatterjee-2020-A novel heme transporter from,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18418,PHI:11401,,no data found,GenBank,AEA93276,,,OG1RF,MntE (OG1RF_10589),,,,,,,1351,Enterococcus faecalis,474186,OG1RF,infective endocarditis,rodents,10090,Mus musculus (related: house mouse),C57BL/6NTac,,,cecum; small intestine; colon,cation efflux family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32229614,PubMed,10.1128/IAI.00058-20,Infect Immun. 2020 May 20;88(6):e00058-20,kkline@ntu.edu.sg,"MntE contributed to colonization of the antibiotic-treated mouse gastrointestinal (GI) tract, suggesting that E. faecalis encounterd excess Mn in this niche.",L N Lam 2020,2020,1 gene,Lam-2020-Enterococcus faecalis Manganese Expor,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18419,PHI:11402,UniProt,A0A1D8PH27,GenBank,AOW27433,,,SC5314,ssy1,chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,gastrointestinal tract,amino acid sensor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32094252,PubMed,10.1128/IAI.00763-19,Infect Immun. 2020 Apr 20;88(5):e00763-19,Michael.Lorenz@uth.tmc.edu,"The ssy1Δ/Δ and stp2Δ/Δ mutants showed reduced fitness in a gastrointestinal (GI) colonization model, yet induced greater damage to epithelial cells and macrophages.",P Miramón 2020,2020,3 genes,Miramón-2020-The Paralogous Transcription Fact,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18420,PHI:11403,UniProt,Q5ANI6,GenBank,AOW28476,,,SC5314,stp1,chromosome 3,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,gastrointestinal tract,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32094252,PubMed,10.1128/IAI.00763-19,Infect Immun. 2020 Apr 20;88(5):e00763-19,Michael.Lorenz@uth.tmc.edu,The stp1Δ/Δ mutant was better able to colonize the gut but the mutation had no effect on host cell damage.,P Miramón 2020,2020,3 genes,Miramón-2020-The Paralogous Transcription Fact,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18421,PHI:11404,UniProt,Q5AL16,GenBank,AOW26940,,,SC5314,stp2,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,gastrointestinal tract,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32094252,PubMed,10.1128/IAI.00763-19,Infect Immun. 2020 Apr 20;88(5):e00763-19,Michael.Lorenz@uth.tmc.edu,"The ssy1Δ/Δ and stp2Δ/Δ mutants showed reduced fitness in a gastrointestinal (GI) colonization model, yet induced greater damage to epithelial cells and macrophages.",P Miramón 2020,2020,3 genes,Miramón-2020-The Paralogous Transcription Fact,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18422,PHI:11403,UniProt,Q5ANI6,GenBank,AOW28476,,,SC5314,stp1,chromosome 3,,,,,PHI:11404,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,gastrointestinal tract,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32094252,PubMed,10.1128/IAI.00763-19,Infect Immun. 2020 Apr 20;88(5):e00763-19,Michael.Lorenz@uth.tmc.edu,"The ssy1Δ/Δ and stp2Δ/Δ mutants showed reduced fitness in a gastrointestinal (GI) colonization model, yet induced greater damage to epithelial cells and macrophages.",P Miramón 2020,2020,3 genes,Miramón-2020-The Paralogous Transcription Fact,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18423,PHI:11404,UniProt,Q5AL16,GenBank,AOW26940,,,SC5314,stp2,chromosome 1,,,,,PHI:11403,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,gastrointestinal tract,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32094252,PubMed,10.1128/IAI.00763-19,Infect Immun. 2020 Apr 20;88(5):e00763-19,Michael.Lorenz@uth.tmc.edu,"The ssy1Δ/Δ and stp2Δ/Δ mutants showed reduced fitness in a gastrointestinal (GI) colonization model, yet induced greater damage to epithelial cells and macrophages.",P Miramón 2020,2020,3 genes,Miramón-2020-The Paralogous Transcription Fact,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18424,PHI:11405,UniProt,W9B383,GenBank,ARA47408,,,AR_0068,dedA,,,,,,,573,Klebsiella pneumoniae,,ATCC 43816; MKP203,pneumonia,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,DedA family inner membrane protein,,,,reduced virulence,,,,,,,,,,no,H2O2; diethylenetriamine NONOate,H2O2: CHEBI:16240; diethylenetriamine NONOate: CHEBI:50154,,,,,gene deletion: full; gene complementation,,,YVS,31988174,PubMed,10.1128/IAI.00034-20,Infect Immun. 2020 Mar 23;88(4):e00034-20,Joan.mecsas@tufts.edu,"Lung infections in mice confirmed roles in K. pneumoniae virulence for the ΔdedA,ΔdsbC,ΔgntR,Δwzm-wzt, ΔyaaA, and ΔycgE mutants, all of which were defective in either capsule content or growth in reactive oxygen or nitrogen species.",M K Paczosa 2020,2020,7 genes,Paczosa-2020-Transposon mutagenesis screen of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18425,PHI:11406,UniProt,A6GV51,GenBank,AEU09842,,,Kp7,dsbC,,,,,,,573,Klebsiella pneumoniae,,ATCC 43816; MKP203,pneumonia,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,thiol:disulfide interchange protein,,,,reduced virulence,,,,,,,,,,no,H2O2; diethylenetriamine NONOate,H2O2: CHEBI:16240; diethylenetriamine NONOate: CHEBI:50154,,,,,gene deletion: full; gene complementation,,,YVS,31988174,PubMed,10.1128/IAI.00034-20,Infect Immun. 2020 Mar 23;88(4):e00034-20,Joan.mecsas@tufts.edu,"Lung infections in mice confirmed roles in K. pneumoniae virulence for the ΔdedA,ΔdsbC,ΔgntR,Δwzm-wzt, ΔyaaA, and ΔycgE mutants, all of which were defective in either capsule content or growth in reactive oxygen or nitrogen species.",M K Paczosa 2020,2020,7 genes,Paczosa-2020-Transposon mutagenesis screen of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18426,PHI:11407,UniProt,A6TAW6,GenBank,ABR77737,,,ATCC 700721; MGH 78578,gntR,,,,,,,573,Klebsiella pneumoniae,,ATCC 43816; MKP203,pneumonia,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,fatty acid metabolism regulator,,,,reduced virulence,,,,,,,,,,no,H2O2; diethylenetriamine NONOate,H2O2: CHEBI:16240; diethylenetriamine NONOate: CHEBI:50154,,,,,gene deletion: full; gene complementation,,,YVS,31988174,PubMed,10.1128/IAI.00034-20,Infect Immun. 2020 Mar 23;88(4):e00034-20,Joan.mecsas@tufts.edu,"Lung infections in mice confirmed roles in K. pneumoniae virulence for the ΔdedA,ΔdsbC,ΔgntR,Δwzm-wzt, ΔyaaA, and ΔycgE mutants, all of which were defective in either capsule content or growth in reactive oxygen or nitrogen species.",M K Paczosa 2020,2020,7 genes,Paczosa-2020-Transposon mutagenesis screen of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18427,PHI:11408,UniProt,A0A378CFB4,GenBank,STV70203,,,NCTC11679,yaaA,,,,,,,573,Klebsiella pneumoniae,,ATCC 43816; MKP203,pneumonia,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,alanine/glycine transport protein,,,,reduced virulence,,,,,,,,,,no,H2O2; diethylenetriamine NONOate,H2O2: CHEBI:16240; diethylenetriamine NONOate: CHEBI:50154,,,,,gene deletion: full; gene complementation,,,YVS,31988174,PubMed,10.1128/IAI.00034-20,Infect Immun. 2020 Mar 23;88(4):e00034-20,Joan.mecsas@tufts.edu,"Lung infections in mice confirmed roles in K. pneumoniae virulence for the ΔdedA,ΔdsbC,ΔgntR,Δwzm-wzt, ΔyaaA, and ΔycgE mutants, all of which were defective in either capsule content or growth in reactive oxygen or nitrogen species.",M K Paczosa 2020,2020,7 genes,Paczosa-2020-Transposon mutagenesis screen of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18428,PHI:11409,UniProt,W9BEV6,GenBank,ARA45326,,,AR_0068,ycgE,,,,,,,573,Klebsiella pneumoniae,,ATCC 43816; MKP203,pneumonia,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,HTH-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,H2O2; diethylenetriamine NONOate,H2O2: CHEBI:16240; diethylenetriamine NONOate: CHEBI:50154,,,,,gene deletion: full; gene complementation,,,YVS,31988174,PubMed,10.1128/IAI.00034-20,Infect Immun. 2020 Mar 23;88(4):e00034-20,Joan.mecsas@tufts.edu,"Lung infections in mice confirmed roles in K. pneumoniae virulence for the ΔdedA,ΔdsbC,ΔgntR,Δwzm-wzt, ΔyaaA, and ΔycgE mutants, all of which were defective in either capsule content or growth in reactive oxygen or nitrogen species.",M K Paczosa 2020,2020,7 genes,Paczosa-2020-Transposon mutagenesis screen of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18429,PHI:11410,UniProt,R4WHP3,GenBank,BAN20050,,,5710/52,wzm,,,,,,,573,Klebsiella pneumoniae,,ATCC 43816; MKP203,pneumonia,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,transport permease protein,,,,reduced virulence,,,,,,,,,,no,H2O2; diethylenetriamine NONOate,H2O2: CHEBI:16240; diethylenetriamine NONOate: CHEBI:50154,,,,,gene deletion: full; gene complementation,,,YVS,31988174,PubMed,10.1128/IAI.00034-20,Infect Immun. 2020 Mar 23;88(4):e00034-20,Joan.mecsas@tufts.edu,"Lung infections in mice confirmed roles in K. pneumoniae virulence for the ΔdedA,ΔdsbC,ΔgntR,Δwzm-wzt, ΔyaaA, and ΔycgE mutants, all of which were defective in either capsule content or growth in reactive oxygen or nitrogen species.",M K Paczosa 2020,2020,7 genes,Paczosa-2020-Transposon mutagenesis screen of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18430,PHI:11411,UniProt,A0A0W8AWM7,GenBank,ARA47379,,,AR_0068,yhbU,,,,,,,573,Klebsiella pneumoniae,,ATCC 43816; MKP203,pneumonia,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,lung,ubiquinone biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; diethylenetriamine NONOate,H2O2: CHEBI:16240; diethylenetriamine NONOate: CHEBI:50154,,,,,gene deletion: full; gene complementation,,,YVS,31988174,PubMed,10.1128/IAI.00034-20,Infect Immun. 2020 Mar 23;88(4):e00034-20,Joan.mecsas@tufts.edu,"Lung infections in mice confirmed roles in K. pneumoniae virulence for the ΔdedA,ΔdsbC,ΔgntR,Δwzm-wzt, ΔyaaA, and ΔycgE mutants, all of which were defective in either capsule content or growth in reactive oxygen or nitrogen species.",M K Paczosa 2020,2020,7 genes,Paczosa-2020-Transposon mutagenesis screen of,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18431,PHI:11412,UniProt,Q8ZJN0,GenBank,CAL18753,,,CO92,pgm,,,,,,,632,Yersinia pestis,214092,CO92,plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; bone marrow-derived macrophage,"2,3-bisphosphoglycerate-independent phosphoglycerate mutase",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31907194,PubMed,10.1128/IAI.00792-19,Infect Immun. 2020 Feb 20;88(3):e00792-19,matthew.nilles@und.edu,Elevated bacterial burdens were found in the spleens of CO92 pgm-infected animals by 24 h postinfection and in the livers by 4 days.,K L O'Donnell 2020,2020,1 gene,O'Donnell-2020-Difference in strain pathogenic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18432,PHI:11412,UniProt,Q8ZJN0,GenBank,CAL18753,,,CO92,pgm,,,,,,,632,Yersinia pestis,,KIM5,plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; bone marrow-derived macrophage,"2,3-bisphosphoglycerate-independent phosphoglycerate mutase",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31907194,PubMed,10.1128/IAI.00792-19,Infect Immun. 2020 Feb 20;88(3):e00792-19,matthew.nilles@und.edu,Elevated bacterial burdens were found in the spleens of CO92 pgm-infected animals by 24 h postinfection and in the livers by 4 days.,K L O'Donnell 2020,2020,1 gene,O'Donnell-2020-Difference in strain pathogenic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18433,PHI:11412,UniProt,Q8ZJN0,GenBank,CAL18753,,,CO92,pgm,,,,,,,632,Yersinia pestis,214092,CO92,plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (TLR2<-/->),,,liver; spleen; bone marrow-derived macrophage,"2,3-bisphosphoglycerate-independent phosphoglycerate mutase",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31907194,PubMed,10.1128/IAI.00792-19,Infect Immun. 2020 Feb 20;88(3):e00792-19,matthew.nilles@und.edu,Elevated bacterial burdens were found in the spleens of CO92 pgm-infected animals by 24 h postinfection and in the livers by 4 days.,K L O'Donnell 2020,2020,1 gene,O'Donnell-2020-Difference in strain pathogenic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18434,PHI:11412,UniProt,Q8ZJN0,GenBank,CAL18753,,,CO92,pgm,,,,,,,632,Yersinia pestis,,KIM5,plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (TLR2<-/->),,,liver; spleen; bone marrow-derived macrophage,"2,3-bisphosphoglycerate-independent phosphoglycerate mutase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31907194,PubMed,10.1128/IAI.00792-19,Infect Immun. 2020 Feb 20;88(3):e00792-19,matthew.nilles@und.edu,Elevated bacterial burdens were found in the spleens of CO92 pgm-infected animals by 24 h postinfection and in the livers by 4 days.,K L O'Donnell 2020,2020,1 gene,O'Donnell-2020-Difference in strain pathogenic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18435,PHI:11412,UniProt,Q8ZJN0,GenBank,CAL18753,,,CO92,pgm,,,,,,,632,Yersinia pestis,,KIM5,plague,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (TLR4<-/->),,,liver; spleen; bone marrow-derived macrophage,"2,3-bisphosphoglycerate-independent phosphoglycerate mutase",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31907194,PubMed,10.1128/IAI.00792-19,Infect Immun. 2020 Feb 20;88(3):e00792-19,matthew.nilles@und.edu,Elevated bacterial burdens were found in the spleens of CO92 pgm-infected animals by 24 h postinfection and in the livers by 4 days.,K L O'Donnell 2020,2020,1 gene,O'Donnell-2020-Difference in strain pathogenic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18436,PHI:11413,UniProt,A0A0D1E1M6,GenBank,KIS68510,,,521,UMAG_03597,chromosome 9,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31802604,PubMed,10.1111/mpp.12893,Mol Plant Pathol. 2020 Feb;21(2):258-271,kheimel@gwdg.de,"UMAG_03597 and UMAG_12184 deletion mutants were not affected in virulence, demonstrating that these genes were dispensable for pathogenic development.",L Schmitz 2019,2019,3 genes,Schmitz-2019-Conditional gene expression revea,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18437,PHI:11414,UniProt,A0A0D1CT94,GenBank,KIS69738,,,521,UMAG_12184,chromosome 5,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),,,,leaf,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31802604,PubMed,10.1111/mpp.12893,Mol Plant Pathol. 2020 Feb;21(2):258-271,kheimel@gwdg.de,"UMAG_03597 and UMAG_12184 deletion mutants were not affected in virulence, demonstrating that these genes were dispensable for pathogenic development.",L Schmitz 2019,2019,3 genes,Schmitz-2019-Conditional gene expression revea,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18438,PHI:11415,UniProt,A0A0D1E1M6,GenBank,KIS68510,,,521,cib1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),,,,leaf,unfolded protein response (UPR) regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31802604,PubMed,10.1111/mpp.12893,Mol Plant Pathol. 2020 Feb;21(2):258-271,kheimel@gwdg.de,Prolonged expression of cib1 is sufficient to overcome the developmental block of Δcib1 strains and initiate pathogenic growth in planta.,L Schmitz 2019,2019,3 genes,Schmitz-2019-Conditional gene expression revea,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18439,PHI:11416,UniProt,P9WK49,GenBank,CCP44008,,,H37Rv,lprE,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,putative lipoprotein,,,,reduced virulence,,,,,,,,wild type,,no,LL-37,LL-37: CHEBI:81664,,,,,gene deletion: full; gene complementation,,,YVS,31619537,PubMed,10.4049/jimmunol.1801301,J Immunol. 2019 Nov 15;203(10):2665-2678,asonawane@iiti.ac.in,Deletion of LprEMtb resulted in reduction of M. tuberculosis virulence in human and mouse macrophages due to upregulation of vitamin D3–responsive cathelicidin expression.,A Padhi 2019,2019,1 gene,Padhi-2019-Mycobacterium tuberculosis LprE Sup,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18440,PHI:11416,UniProt,P9WK49,GenBank,CCP44008,,,H37Rv,lprE,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,putative lipoprotein,,,,reduced virulence,,,,,,,,wild type,,no,LL-37,LL-37: CHEBI:81664,,,,,gene deletion: full; gene complementation,,,YVS,31619537,PubMed,10.4049/jimmunol.1801301,J Immunol. 2019 Nov 15;203(10):2665-2678,asonawane@iiti.ac.in,Deletion of LprEMtb resulted in reduction of M. tuberculosis virulence in human and mouse macrophages due to upregulation of vitamin D3–responsive cathelicidin expression.,A Padhi 2019,2019,1 gene,Padhi-2019-Mycobacterium tuberculosis LprE Sup,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18441,PHI:11416,UniProt,P9WK49,GenBank,CCP44008,,,H37Rv,lprE,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,putative lipoprotein,,,,reduced virulence,,,,,,,,wild type,,no,LL-37,LL-37: CHEBI:81664,,,,,gene deletion: full; gene complementation,,,YVS,31619537,PubMed,10.4049/jimmunol.1801301,J Immunol. 2019 Nov 15;203(10):2665-2678,asonawane@iiti.ac.in,Deletion of LprEMtb resulted in reduction of M. tuberculosis virulence in human and mouse macrophages due to upregulation of vitamin D3–responsive cathelicidin expression.,A Padhi 2019,2019,1 gene,Padhi-2019-Mycobacterium tuberculosis LprE Sup,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18442,PHI:11417,UniProt,A0A0D6I7L0,GenBank,ALD83590,,,3232,ppiA,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,peptidyl-prolyl cis-trans isomerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31111418,PubMed,10.1007/s12223-019-00717-z,Folia Microbiol (Praha). 2020 Feb;65(1):161-171,sahlawat64@gmail.com,Single-gene deletion mutant strains were more susceptible to the stationary phase of growth and heat stress conditions and showed reduced survival within macrophage cell line.,M Kumawat 2019,2019,3 genes,Kumawat-2019-Comparative evaluation of structu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18443,PHI:11418,UniProt,A0A0F7DI09,GenBank,ALD83591,,,3232,ppiB,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,peptidyl-prolyl cis-trans isomerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31111418,PubMed,10.1007/s12223-019-00717-z,Folia Microbiol (Praha). 2020 Feb;65(1):161-171,sahlawat64@gmail.com,Single-gene deletion mutant strains were more susceptible to the stationary phase of growth and heat stress conditions and showed reduced survival within macrophage cell line.,M Kumawat 2019,2019,3 genes,Kumawat-2019-Comparative evaluation of structu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18444,PHI:11419,UniProt,A0A0F7DJX4,GenBank,ALD83589,,,3232,ppiC,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,peptidyl-prolyl cis-trans isomerase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31111418,PubMed,10.1007/s12223-019-00717-z,Folia Microbiol (Praha). 2020 Feb;65(1):161-171,sahlawat64@gmail.com,Single-gene deletion mutant strains were more susceptible to the stationary phase of growth and heat stress conditions and showed reduced survival within macrophage cell line.,M Kumawat 2019,2019,3 genes,Kumawat-2019-Comparative evaluation of structu,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18445,PHI:11420,UniProt,Q7A1N5,GenBank,BAB94445,,,MW2,sarA,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,osteomyelitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,femur,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31722523,PubMed,10.1021/acsinfecdis.9b00291,ACS Infect Dis. 2020 Feb 14;6(2):237-249,smeltzermarks@uams.edu,Mutation of saeRS or sarA attenuated the virulence of LAC in osteomyelitis to a comparable degree.,A M Ramirez 2019,2019,3 genes,Ramirez-2019-Exploiting Correlations between P,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18446,PHI:11421,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,PHI:11422,1280,Staphylococcus aureus,367830,USA300 LAC,osteomyelitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,femur,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31722523,PubMed,10.1021/acsinfecdis.9b00291,ACS Infect Dis. 2020 Feb 14;6(2):237-249,smeltzermarks@uams.edu,Mutation of saeRS or sarA attenuated the virulence of LAC in osteomyelitis to a comparable degree.,A M Ramirez 2019,2019,3 genes,Ramirez-2019-Exploiting Correlations between P,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18447,PHI:11422,UniProt,Q2G2U1,GenBank,CAD89115,,,ISP479C,saeS,,,,,,PHI:11421,1280,Staphylococcus aureus,367830,USA300 LAC,osteomyelitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,femur,histidine protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31722523,PubMed,10.1021/acsinfecdis.9b00291,ACS Infect Dis. 2020 Feb 14;6(2):237-249,smeltzermarks@uams.edu,Mutation of saeRS or sarA attenuated the virulence of LAC in osteomyelitis to a comparable degree.,A M Ramirez 2019,2019,3 genes,Ramirez-2019-Exploiting Correlations between P,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18448,PHI:11420,UniProt,Q7A1N5,GenBank,BAB94445,,,MW2,sarA,,,,,,PHI:11421; PHI:11422,1280,Staphylococcus aureus,367830,USA300 LAC,osteomyelitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,femur,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31722523,PubMed,10.1021/acsinfecdis.9b00291,ACS Infect Dis. 2020 Feb 14;6(2):237-249,smeltzermarks@uams.edu,Mutation of saeRS or sarA attenuated the virulence of LAC in osteomyelitis to a comparable degree.,A M Ramirez 2019,2019,3 genes,Ramirez-2019-Exploiting Correlations between P,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18449,PHI:11421,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,PHI:11420; PHI:11422,1280,Staphylococcus aureus,367830,USA300 LAC,osteomyelitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,femur,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31722523,PubMed,10.1021/acsinfecdis.9b00291,ACS Infect Dis. 2020 Feb 14;6(2):237-249,smeltzermarks@uams.edu,Mutation of saeRS or sarA attenuated the virulence of LAC in osteomyelitis to a comparable degree.,A M Ramirez 2019,2019,3 genes,Ramirez-2019-Exploiting Correlations between P,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18450,PHI:11422,UniProt,Q2G2U1,GenBank,CAD89115,,,ISP479C,saeS,,,,,,PHI:11420; PHI:11421,1280,Staphylococcus aureus,367830,USA300 LAC,osteomyelitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,femur,histidine protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,31722523,PubMed,10.1021/acsinfecdis.9b00291,ACS Infect Dis. 2020 Feb 14;6(2):237-249,smeltzermarks@uams.edu,Mutation of saeRS or sarA attenuated the virulence of LAC in osteomyelitis to a comparable degree.,A M Ramirez 2019,2019,3 genes,Ramirez-2019-Exploiting Correlations between P,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18451,PHI:11423,UniProt,P33546,GenBank,AF348706_139,,,M90T,icsB,,,,,,,623,Shigella flexneri,,serotype 2a strain 2457T,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30061757,PubMed,10.1038/s41564-018-0215-6,Nat Microbiol. 2018 Sep;3(9):996-1009,shaofeng@nibs.ac.cn,"IcsB disrupted the actin cytoskeleton in eukaryotes, resulting from N(epsilon)-fatty acylation of RhoGTPases on lysine residues in their polybasic region.",W Liu 2018,2018,1 gene,Liu-2018-N(epsilon)-fatty acylation of multipl,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18452,PHI:11424,UniProt,J9VKE7,GenBank,AFR93886,,,H99,zrc1 (CNAG_02806),chromosome 3,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,vacuolar zinc transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29299844,PubMed,10.1007/s12275-018-7475-y,J Microbiol. 2018 Jan;56(1):65-71,whjung@cau.ac.kr,Zrc1-mediated zinc detoxification was not required for the virulence of C. neoformans,M Cho 2018,2018,2 genes,Cho-2018-Vacuolar zinc transporter Zrc1 is req,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18453,PHI:11424,UniProt,J9VKE7,GenBank,AFR93886,,,H99,zrc1 (CNAG_02806),chromosome 3,,,,,PHI:11425,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,vacuolar zinc transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29299844,PubMed,10.1007/s12275-018-7475-y,J Microbiol. 2018 Jan;56(1):65-71,whjung@cau.ac.kr,Zrc1-mediated zinc detoxification was not required for the virulence of C. neoformans,M Cho 2018,2018,2 genes,Cho-2018-Vacuolar zinc transporter Zrc1 is req,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18454,PHI:11425,UniProt,J9VT55,GenBank,AFR97418,,,H99,zip1,chromosome 10,,,,,PHI:11424,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,regulatory protein cys-3,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29299844,PubMed,10.1007/s12275-018-7475-y,J Microbiol. 2018 Jan;56(1):65-71,whjung@cau.ac.kr,Zrc1-mediated zinc detoxification was not required for the virulence of C. neoformans,M Cho 2018,2018,2 genes,Cho-2018-Vacuolar zinc transporter Zrc1 is req,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18455,PHI:11426,UniProt,Q04M32,GenBank,ABJ55451,,,D39,ilvC (SPD_0406),,,,,,,1313,Streptococcus pneumoniae,373153,D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung; spleen; blood,ketol-acid reductoisomerase (NADP(+)),,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28735462,PubMed,10.1007/s12272-017-0931-0,Arch Pharm Res. 2017 Aug;40(8):921-932,dkrhee@skku.edu,"Downregulation of BCAA biosynthesis by ilvC ablation diminished BCAA concentration and expression of pneumolysin (Ply) and LytA, and subsequently attenuated virulence.",G L Kim 2017,2017,1 gene,Kim-2017-Effect of decreased BCAA synthesis th,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18456,PHI:11427,,no data found,,,,,,LSG1,,,,,,PHI:11428; PHI:11429; PHI:11430; PHI:11431,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,20 kb Vl43 lineage-specific (LS) region,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18457,PHI:11428,,no data found,,,,,,LSG2,,,,,,PHI:11427; PHI:11429; PHI:11430; PHI:11431,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,20 kb Vl43 lineage-specific (LS) region,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18458,PHI:11429,,no data found,,,,,,LSG3,,,,,,PHI:11427; PHI:11428; PHI:11430; PHI:11431,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18459,PHI:11430,,no data found,,,,,,LSG4,,,,,,PHI:11427; PHI:11428; PHI:11429; PHI:11431,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,20 kb Vl43 lineage-specific (LS) region,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18460,PHI:11431,,no data found,,,,,,LSG5,,,,,,PHI:11427; PHI:11428; PHI:11429; PHI:11430,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,20 kb Vl43 lineage-specific (LS) region,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18461,PHI:11432,,no data found,,,,,,LSG6,,,,,,PHI:11433,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18462,PHI:11433,,no data found,,,,,,LSG7,,,,,,PHI:11432; PHI:11433; PHI:11434; PHI:11435; PHI:11436; PHI:11437,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,20 kb Vl43 lineage-specific (LS) region,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18463,PHI:11427,,no data found,,,,,,LSG1,,,,,,PHI:11428; PHI:11429; PHI:11430; PHI:11431; PHI:11432; PHI:11433,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,20 kb Vl43 lineage-specific (LS) region,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18464,PHI:11428,,no data found,,,,,,LSG2,,,,,,PHI:11427; PHI:11429; PHI:11430; PHI:11431; PHI:11432; PHI:11433,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,20 kb Vl43 lineage-specific (LS) region,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18465,PHI:11429,,no data found,,,,,,LSG3,,,,,,PHI:11427; PHI:11428; PHI:11430; PHI:11431; PHI:11432; PHI:11433,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18466,PHI:11430,,no data found,,,,,,LSG4,,,,,,PHI:11427; PHI:11428; PHI:11429; PHI:11431; PHI:11432; PHI:11433,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,20 kb Vl43 lineage-specific (LS) region,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18467,PHI:11431,,no data found,,,,,,LSG5,,,,,,PHI:11427; PHI:11428; PHI:11429; PHI:11430; PHI:11432; PHI:11433,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,20 kb Vl43 lineage-specific (LS) region,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18468,PHI:11432,,no data found,,,,,,LSG6,,,,,,PHI:11427; PHI:11428; PHI:11429; PHI:11430; PHI:11431; PHI:11433,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18469,PHI:11433,,no data found,,,,,,LSG7,,,,,,PHI:11427; PHI:11428; PHI:11429; PHI:11430; PHI:11431; PHI:11432,100787,Verticillium longisporum,,Vl43,wilt,eudicots,3708,Brassica napus (related: rape),,,,leaf,20 kb Vl43 lineage-specific (LS) region,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,33955130,PubMed,10.1111/mpp.13071,Mol Plant Pathol. 2021 May 5,gbraus@gwdg.de,Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed.,R Harting 2021,2021,7 genes,Harting-2021-A 20-kb lineage-specific genomic,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18470,PHI:11434,UniProt,J9VH50,GenBank,AFR92701,,,H99,Pkr1 (CNAG_00570),chromosome 1,,,,,,5207,Cryptococcus neoformans,,Ftc555-1,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,AMP-dependent protein kinase regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33906924,PubMed,10.1128/mBio.00567-21,mBio. 2021 Apr 27;12(2):e00567-21,acasade1@jhu.edu,Isolates derived from environmental strains gained the capacity for enhanced macrophage toxicity after amoeba selection and carried mutations on the CNAG_00570 gene encoding Pkr1 (AMP-dependent protein kinase regulator) but manifested reduced virulence in mice because they elicited more effective fungal-clearing immune responses.,M S Fu 2021,2021,1 gene,Fu-2021-Amoeba Predation of Cryptococcus neofo,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18471,PHI:11434,UniProt,J9VH50,GenBank,AFR92701,,,H99,Pkr1 (CNAG_00570),chromosome 1,,,,,,5207,Cryptococcus neoformans,,Ftc555-1,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung,AMP-dependent protein kinase regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33906924,PubMed,10.1128/mBio.00567-21,mBio. 2021 Apr 27;12(2):e00567-21,acasade1@jhu.edu,Isolates derived from environmental strains gained the capacity for enhanced macrophage toxicity after amoeba selection and carried mutations on the CNAG_00570 gene encoding Pkr1 (AMP-dependent protein kinase regulator) but manifested reduced virulence in mice because they elicited more effective fungal-clearing immune responses.,M S Fu 2021,2021,1 gene,Fu-2021-Amoeba Predation of Cryptococcus neofo,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18472,PHI:11434,UniProt,J9VH50,GenBank,AFR92701,,,H99,Pkr1 (CNAG_00570),chromosome 1,,,,,,5207,Cryptococcus neoformans,,Ftc555-1,fungal meningitis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,AMP-dependent protein kinase regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,33906924,PubMed,10.1128/mBio.00567-21,mBio. 2021 Apr 27;12(2):e00567-21,acasade1@jhu.edu,Isolates derived from environmental strains gained the capacity for enhanced macrophage toxicity after amoeba selection and carried mutations on the CNAG_00570 gene encoding Pkr1 (AMP-dependent protein kinase regulator) but manifested reduced virulence in mice because they elicited more effective fungal-clearing immune responses.,M S Fu 2021,2021,1 gene,Fu-2021-Amoeba Predation of Cryptococcus neofo,BATCH_106B,2021-06-01,MC,,,,,,,,,,,,,
,,Record 18473,PHI:11435,,no data found,,,,,,pacC,,,,,,,40993,Aspergillus carbonarius,,NRRL 368,grape rot,eudicots,3760,Prunus persica (related: peach),var. nucipersica cv. Sun Snow,,,fruit,pH-responsive transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32117191,PubMed,10.3389/fmicb.2020.00210,Front Microbiol. 2020 Feb 13;11:210,edwardsio@volcani.agri.gov.il,"ΔAcpacC mutant displayed an acidity-mimicking phenotype, which resulted in impaired fungal growth at neutral/alkaline pH, accompanied by reduced sporulation and conidial germination compared to the wild type (WT) strain.",O Barda 2020,2020,1 gene,Barda-2020-The pH-Responsive Transcription Fac,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18474,PHI:11435,,no data found,,,,,,pacC,,,,,,,40993,Aspergillus carbonarius,,NRRL 368,grape rot,eudicots,29760,Vitis vinifera (related: wine grape),cv. Zani,,,fruit,pH-responsive transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32117191,PubMed,10.3389/fmicb.2020.00210,Front Microbiol. 2020 Feb 13;11:210,edwardsio@volcani.agri.gov.il,"ΔAcpacC mutant displayed an acidity-mimicking phenotype, which resulted in impaired fungal growth at neutral/alkaline pH, accompanied by reduced sporulation and conidial germination compared to the wild type (WT) strain.",O Barda 2020,2020,1 gene,Barda-2020-The pH-Responsive Transcription Fac,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18475,PHI:11436,UniProt,A0A5P8YDS3,GenBank,AAS63577,,,91001,yp_3416,,,,,,,632,Yersinia pestis,992166,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,E3 ubiquitin ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33631294,PubMed,10.1016/j.mcpro.2021.100066,Mol Cell Proteomics. 2021 Feb 22;20:100066,dht@mail.tsinghua.edu.cn,The yp_3416~3418 deletion mutant of Y. pestis showed significant virulence attenuation in mice.,S Cao 2021,2021,2 genes,Cao-2021-Secretome and Comparative Proteomics,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18476,PHI:11437,UniProt,A0A5P8YCN0,GenBank,AAS63579,,,91001,yp_3418,,,,,,,632,Yersinia pestis,992166,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,E3 ubiquitin ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33631294,PubMed,10.1016/j.mcpro.2021.100066,Mol Cell Proteomics. 2021 Feb 22;20:100066,dht@mail.tsinghua.edu.cn,The yp_3416~3418 deletion mutant of Y. pestis showed significant virulence attenuation in mice.,S Cao 2021,2021,2 genes,Cao-2021-Secretome and Comparative Proteomics,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18477,PHI:11436,UniProt,A0A5P8YDS3,GenBank,AAS63577,,,91001,yp_3416,,,,,,PHI:11437,632,Yersinia pestis,992166,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,E3 ubiquitin ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33631294,PubMed,10.1016/j.mcpro.2021.100066,Mol Cell Proteomics. 2021 Feb 22;20:100066,dht@mail.tsinghua.edu.cn,The yp_3416~3418 deletion mutant of Y. pestis showed significant virulence attenuation in mice.,S Cao 2021,2021,2 genes,Cao-2021-Secretome and Comparative Proteomics,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18478,PHI:11437,UniProt,A0A5P8YCN0,GenBank,AAS63579,,,91001,yp_3418,,,,,,PHI:11436,632,Yersinia pestis,992166,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,E3 ubiquitin ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33631294,PubMed,10.1016/j.mcpro.2021.100066,Mol Cell Proteomics. 2021 Feb 22;20:100066,dht@mail.tsinghua.edu.cn,The yp_3416~3418 deletion mutant of Y. pestis showed significant virulence attenuation in mice.,S Cao 2021,2021,2 genes,Cao-2021-Secretome and Comparative Proteomics,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18479,PHI:11438,UniProt,P0C0B9,GenBank,AAK33487,,,SF370,bglB,,,,,,,1314,Streptococcus pyogenes,,5448,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,soft-tissue,putative phospho--glucosidase,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32719156,PubMed,10.1128/IAI.00346-20,Infect Immun. 2020 Sep 18;88(10):e00346-20,kmciver@umd.edu,Loss of bglP and bglB caused more severe localized soft tissue infections.,R E Braza 2020,2020,2 genes,Braza-2020-PTS Uptake and Metabolism of the ß-,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18480,PHI:11439,UniProt,Q9A142,GenBank,AAK33486,,,SF370,bglP,,,,,,,1314,Streptococcus pyogenes,,5448,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,soft-tissue,beta-glucoside permease,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32719156,PubMed,10.1128/IAI.00346-20,Infect Immun. 2020 Sep 18;88(10):e00346-20,kmciver@umd.edu,Loss of bglP and bglB caused more severe localized soft tissue infections.,R E Braza 2020,2020,2 genes,Braza-2020-PTS Uptake and Metabolism of the ß-,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18481,PHI:11438,UniProt,P0C0B9,GenBank,AAK33487,,,SF370,bglB,,,,,,PHI:11439,1314,Streptococcus pyogenes,,5448,infection,primates,9606,Homo sapiens (related: human),,,,blood,putative phospho--glucosidase,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32719156,PubMed,10.1128/IAI.00346-20,Infect Immun. 2020 Sep 18;88(10):e00346-20,kmciver@umd.edu,Loss of bglP and bglB caused more severe localized soft tissue infections.,R E Braza 2020,2020,2 genes,Braza-2020-PTS Uptake and Metabolism of the ß-,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18482,PHI:11439,UniProt,Q9A142,GenBank,AAK33486,,,SF370,bglP,,,,,,PHI:11438,1314,Streptococcus pyogenes,,5448,infection,primates,9606,Homo sapiens (related: human),,,,blood,beta-glucoside permease,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32719156,PubMed,10.1128/IAI.00346-20,Infect Immun. 2020 Sep 18;88(10):e00346-20,kmciver@umd.edu,Loss of bglP and bglB caused more severe localized soft tissue infections.,R E Braza 2020,2020,2 genes,Braza-2020-PTS Uptake and Metabolism of the ß-,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18483,PHI:11439,UniProt,Q9A142,GenBank,AAK33486,,,SF370,bglP,,,,,,,1314,Streptococcus pyogenes,,5448,infection,primates,9606,Homo sapiens (related: human),,,,blood,beta-glucoside permease,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32719156,PubMed,10.1128/IAI.00346-20,Infect Immun. 2020 Sep 18;88(10):e00346-20,kmciver@umd.edu,Loss of bglP and bglB caused more severe localized soft tissue infections.,R E Braza 2020,2020,2 genes,Braza-2020-PTS Uptake and Metabolism of the ß-,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18484,PHI:11440,UniProt,P31780,GenBank,CAA47124,,,Ah65,exeD,,,,,,,644,Aeromonas hydrophila,,vAh ML09-119,diarrhea; nausea; vomiting,bony fishes,7998,Ictalurus punctatus (related: Channel catfish),,,,abdomen; liver; head; trunk kidney,secretin,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33088835,PubMed,10.3389/fvets.2020.574113,Front Vet Sci. 2020 Sep 25;7:574113,newtojc@auburn.edu,In vivo challenges in channel catfish resulted in complete attenuation of virulence in ML09-119 exeD deletion mutant.,P C Barger 2020,2020,1 gene,Barger-2020-Type II Secretion Is Essential for,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18485,PHI:11441,,no data found,,,,,,UvRpd3,,,,UvSlt2,UniProt: no data found; GenBank: no data found,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,spikelet,Zn-binding reduced potassium dependency 3-type histone deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33427395,PubMed,10.1111/jipb.13066,J Integr Plant Biol. 2021 Feb;63(2):409-425,luzheng@mail.hzau.edu.cn,UvRpd3 is important for Khib removal and virulence of U. virens.,X Chen 2021,2021,2 genes,Chen-2021-Comprehensive identification of lysi,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18486,PHI:11442,,no data found,,,,,,UvSlt2,,"single point mutation strains (UvSlt2 K53R-1, UvSlt2 K53R-2, UvSlt2 K60R-1, and UvSlt2 K60R-2), and the double point-mutation strains (UvSlt2 K53R/K60R-1 and UvSlt2 K53R/K60R-2)",,UvRpd3,UniProt: no data found; GenBank: no data found,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,spikelet,mitogen-activated protein kinase,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,33427395,PubMed,10.1111/jipb.13066,J Integr Plant Biol. 2021 Feb;63(2):409-425,luzheng@mail.hzau.edu.cn,Mutation of 2-hydroxyisobutyrylation sites in the MAPK UvSlt2 caused reduced fungal virulence and enzymatic activity of UvSlt2.,X Chen 2021,2021,2 genes,Chen-2021-Comprehensive identification of lysi,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18487,PHI:11443,UniProt,A0A0K6FTM3,GenBank,CUA69457,,,BBA 69670,RsRplA,,,,,,,456999,Rhizoctonia solani,,strain AG2-2IIIB isolate BBA 69670,sheath blight (rice),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33138028,PubMed,10.3390/ijms21218070,Int J Mol Sci. 2020 Oct 29;21(21):8070,Georgios.tzelepis@slu.se,"The RsRlpA gene was highly induced upon early-stage infection of sugar beet seedlings, and heterologous expression in Cercospora beticola demonstrated involvement in virulence.",S N Charova 2020,2020,1 gene,Charova-2020-The RsRlpA Effector Is a Protease,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18488,PHI:11443,UniProt,A0A0K6FTM3,GenBank,CUA69457,,,BBA 69670,RsRplA,,,,,,,122368,Cercospora beticola,,Ty1,leaf spot (sugar beet),eudicots,161934,Beta vulgaris (related: beet),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,heterologous expression,,,YVS,33138028,PubMed,10.3390/ijms21218070,Int J Mol Sci. 2020 Oct 29;21(21):8070,Georgios.tzelepis@slu.se,"The RsRlpA gene was highly induced upon early-stage infection of sugar beet seedlings, and heterologous expression in Cercospora beticola demonstrated involvement in virulence.",S N Charova 2020,2020,1 gene,Charova-2020-The RsRlpA Effector Is a Protease,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18489,PHI:11443,UniProt,A0A0K6FTM3,GenBank,CUA69457,,,BBA 69670,RsRplA,,,,,,,456999,Rhizoctonia solani,,strain AG2-2IIIB isolate BBA 69670,sheath blight (rice),eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,33138028,PubMed,10.3390/ijms21218070,Int J Mol Sci. 2020 Oct 29;21(21):8070,Georgios.tzelepis@slu.se,"The RsRlpA gene was highly induced upon early-stage infection of sugar beet seedlings, and heterologous expression in Cercospora beticola demonstrated involvement in virulence.",S N Charova 2020,2020,1 gene,Charova-2020-The RsRlpA Effector Is a Protease,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18490,PHI:11444,UniProt,M5C8P6,GenBank,CCO32177,,,isolate 7/3/14,RsLysM,,,,,,,122368,Cercospora beticola,,Ty1,leaf spot (sugar beet),eudicots,161934,Beta vulgaris (related: beet),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,heterologous expression,,,YVS,31076860,PubMed,10.1007/s00438-019-01573-9,Mol Genet Genomics. 2019 Oct;294(5):1211-1218,Georgios.Tzelepis@slu.se,"When RsLysM was heterologously expressed in Cercospora beticola, necrotic lesion size and fungal colonization ability were increased, indicating a role in virulence.",F Dolfors 2019,2019,1 gene,Dolfors-2019-A LysM effector protein from the,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18491,PHI:11444,UniProt,M5C8P6,GenBank,CCO32177,,,isolate 7/3/14,RsLysM,,,,,,,456999,Rhizoctonia solani,,strain AG2-2IIIB isolate BBA 69670,sheath blight (rice),eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,31076860,PubMed,10.1007/s00438-019-01573-9,Mol Genet Genomics. 2019 Oct;294(5):1211-1218,Georgios.Tzelepis@slu.se,"When RsLysM was heterologously expressed in Cercospora beticola, necrotic lesion size and fungal colonization ability were increased, indicating a role in virulence.",F Dolfors 2019,2019,1 gene,Dolfors-2019-A LysM effector protein from the,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18492,PHI:11445,UniProt,A0A7U4RTD8,GenBank,AKJ34468,,,NJ-35,lahS,,,,,,,644,Aeromonas hydrophila,1416915,NJ-35,diarrhea; nausea; vomiting,bony fishes,7955,Danio rerio (related: zebrafish),,,,,LysR family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,30208624,PubMed,10.3390/ijms19092709,Int J Mol Sci. 2018 Sep 11;19(9):2709,liuyongjie@njau.edu.cn,"The deletion of lahS caused bacteria to exhibit significantly decreased hemolytic activity, motility, biofilm formation, protease production, and anti-bacterial competition ability when compared to the wild-type strain.",Y Dong 2018,2018,1 gene,Dong-2018-Discovery of lahS as a Global Regula,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18493,PHI:11446,UniProt,P0DUJ7,GenBank,CBW18025,,,SL1344,sseK3,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,conserved sORF,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33012979,PubMed,no data found,Can J Vet Res. 2020 Oct;84(4):302-309,cjzhang@sina.com,"The sseK3 deletion mutant exhibited adhesion and invasion properties similar to those of wild-type (WT) S. Typhimurium, although the virulence and intracellular proliferation of the mutant were significantly reduced compared to that of the WT strain.",F Du 2020,2020,1 gene,Du-2020-Salmonella enterica serovar Typhimuriu,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18494,PHI:11447,UniProt,A3M3S7,GenBank,ABO11571,,,ATCC 17978,csrA,,,,,,,470,Acinetobacter baumannii,,ATCC 17961,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,carbon storage regulator,,,,reduced virulence,,,,,,,,,,no,sodium chloride (NaCl); sucrose: CHEBI:17992,sodium chloride (NaCl): CHEBI:26710; sucrose: CHEBI:17992,,,,,gene deletion: full; gene complementation,,,YVS,32989034,PubMed,10.1128/IAI.00259-20,Infect Immun. 2020 Nov 16;88(12):e00259-20,pescie@ecu.edu,"The ΔcsrA mutant strains had a greatly reduced ability to kill Galleria mellonella larvae, could not replicate in G. mellonella hemolymph, and also had a growth defect in human serum.",J M Farrow 2020,2020,1 gene,Farrow-2020-CsrA Supports both Environmental P,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18495,PHI:11447,UniProt,A3M3S7,GenBank,ABO11571,,,ATCC 17978,csrA,,,,,,,470,Acinetobacter baumannii,,AB09-003,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,carbon storage regulator,,,,reduced virulence,,,,,,,,,,no,sodium chloride (NaCl); sucrose: CHEBI:17992,sodium chloride (NaCl): CHEBI:26710; sucrose: CHEBI:17992,,,,,gene deletion: full; gene complementation,,,YVS,32989034,PubMed,10.1128/IAI.00259-20,Infect Immun. 2020 Nov 16;88(12):e00259-20,pescie@ecu.edu,"The ΔcsrA mutant strains had a greatly reduced ability to kill Galleria mellonella larvae, could not replicate in G. mellonella hemolymph, and also had a growth defect in human serum.",J M Farrow 2020,2020,1 gene,Farrow-2020-CsrA Supports both Environmental P,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18496,PHI:11448,UniProt,A0A1R3RGK4,GenBank,OOF93603,,,ITEM 5010,AcOTAbZIP,,,,,,,40993,Aspergillus carbonarius,,AC49,grape rot,eudicots,29760,Vitis vinifera (related: wine grape),cv. Italia,,,fruit,bZip transcription factor,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,YVS,33540740,PubMed,10.3390/toxins13020111,Toxins (Basel). 2021 Feb 2;13(2):111,ritamilvia.demiccolisangelini@uniba.it,OTA was not required by A. carbonarius for the pathogenicity process.,D Gerin 2021,2021,1 gene,Gerin-2021-Functional Role of Aspergillus carb,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18497,PHI:11449,UniProt,D3H539,GenBank,CBG27800,,,042,aafA,,,,,,,562,Escherichia coli,216592,EAEC 042,diarrhea,primates,9606,Homo sapiens (related: human),,,,colon; duodenum,major fimbrial subunit of aggregative adherence fimbria II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32631917,PubMed,10.1128/IAI.00176-20,Infect Immun. 2020 Aug 19;88(9):e00176-20,lap5b@virginia.edu,"A null mutant in aafA, the major subunit of AAF/II, adhered signi?cantly less than wild-type (WT) EAEC strain 042.",L A Gonyar 2020,2020,1 gene,Gonyar-2020-Aggregative Adherence Fimbriae II,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18498,PHI:11450,UniProt,A0A1S6GXE3,,,,,,fba (MBOV_RS00435),,,,,,,28903,Mycoplasmopsis bovis,767465,HB0801,,even-toed ungulates,9913,Bos taurus (related: cattle),EBL cell line,,,embryonic bovine lung cell,"fructose-1,6-bisphosphate aldolase",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: recombinant protein,,,YVS,30852357,PubMed,10.1016/j.rvsc.2019.02.010,Res Vet Sci. 2019 Jun;124:70-78,chenxi@mail.hzau.edu.cn,rFBA was able to adhere to embryonic bovine lung (EBL) cells.,J Huang 2019,2019,1 gene,"Huang-2019-Fructose-1,6-bisphosphate aldolase",BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18499,PHI:11451,UniProt,D4HVH6,GenBank,CBA21073,,,CFPB1430,rfbX,,rfbX::Tn5 mutant,,,,,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot; fruit,putative PST family transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,YVS,32839177,PubMed,10.1128/JB.00390-20,J Bacteriol. 2020 Oct 22;202(22):e00390-20,twm4@psu.edu,Mutations in rfbX disrupted amylovoran production and virulence in apple fruits and treeshoots and the deletion of yibD suppressed the rfbX mutant phenotype.,S M Klee 2020,2020,2 genes,Klee-2020-Virulence genetics of an Erwinia amy,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18500,PHI:11451,UniProt,D4HVH6,GenBank,CBA21073,,,CFPB1430,rfbX,,,,,,,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot; fruit,putative PST family transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32839177,PubMed,10.1128/JB.00390-20,J Bacteriol. 2020 Oct 22;202(22):e00390-20,twm4@psu.edu,Mutations in rfbX disrupted amylovoran production and virulence in apple fruits and treeshoots and the deletion of yibD suppressed the rfbX mutant phenotype.,S M Klee 2020,2020,2 genes,Klee-2020-Virulence genetics of an Erwinia amy,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18501,PHI:11452,UniProt,D4HVH7,GenBank,CBA21075,,,CFPB1430,yibD,,,,,,,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot; fruit,uncharacterized glycosyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32839177,PubMed,10.1128/JB.00390-20,J Bacteriol. 2020 Oct 22;202(22):e00390-20,twm4@psu.edu,Mutations in rfbX disrupted amylovoran production and virulence in apple fruits and treeshoots and the deletion of yibD suppressed the rfbX mutant phenotype.,S M Klee 2020,2020,2 genes,Klee-2020-Virulence genetics of an Erwinia amy,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18502,PHI:11452,UniProt,D4HVH7,GenBank,CBA21075,,,CFPB1430,yibD,,,,,,PHI:11451,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot; fruit,uncharacterized glycosyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32839177,PubMed,10.1128/JB.00390-20,J Bacteriol. 2020 Oct 22;202(22):e00390-20,twm4@psu.edu,Mutations in rfbX disrupted amylovoran production and virulence in apple fruits and treeshoots and the deletion of yibD suppressed the rfbX mutant phenotype.,S M Klee 2020,2020,2 genes,Klee-2020-Virulence genetics of an Erwinia amy,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18503,PHI:11451,UniProt,D4HVH6,GenBank,CBA21073,,,CFPB1430,rfbX,,,,,,PHI:11452,552,Erwinia amylovora,665029,CFBP 1430,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot; fruit,putative PST family transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32839177,PubMed,10.1128/JB.00390-20,J Bacteriol. 2020 Oct 22;202(22):e00390-20,twm4@psu.edu,Mutations in rfbX disrupted amylovoran production and virulence in apple fruits and treeshoots and the deletion of yibD suppressed the rfbX mutant phenotype.,S M Klee 2020,2020,2 genes,Klee-2020-Virulence genetics of an Erwinia amy,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18504,PHI:11453,UniProt,B0XMW7,GenBank,EDP55659,,,A1163,erg24A (AFUB_003560),,,,,,,746128,Aspergillus fumigatus,,A1160 (Δaku80 pyrG1 pyrG),invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sterol C-14 reductase,,,,reduced virulence,,,,,,reduced,,reduced,,no,voriconazole; itraconazole; amphotericin B; terbinafine,voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; amphotericin B: CHEBI:2682; terbinafine: CHEBI:9448,,,,,gene deletion: full; gene complementation,,,YVS,33475797,PubMed,10.1007/s00253-021-11104-5,Appl Microbiol Biotechnol. 2021 Feb;105(3):1253-1268,linglu@njnu.edu.cn,"Loss of one homolog of Erg24 impairs hyphal growth, conidiation, and virulence but has no effect on ergosterol biosynthesis.",Y Li 2021,2021,2 genes,Li-2021-The sterol C-14 reductase Erg24 is res,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18505,PHI:11454,UniProt,B0XMW7,GenBank,EDP55659,,,A1163,erg24B (AFUB_006090),,,,,,,746128,Aspergillus fumigatus,,A1160 (Δaku80 pyrG1 pyrG),invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sterol C-14 reductase,,,,reduced virulence,,,,,,reduced,,reduced,,no,voriconazole; itraconazole; amphotericin B; terbinafine,voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; amphotericin B: CHEBI:2682; terbinafine: CHEBI:9448,,,,,gene deletion: full; gene complementation,,,YVS,33475797,PubMed,10.1007/s00253-021-11104-5,Appl Microbiol Biotechnol. 2021 Feb;105(3):1253-1268,linglu@njnu.edu.cn,"Loss of one homolog of Erg24 impairs hyphal growth, conidiation, and virulence but has no effect on ergosterol biosynthesis.",Y Li 2021,2021,2 genes,Li-2021-The sterol C-14 reductase Erg24 is res,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18506,PHI:11455,UniProt,S8ENF7,GenBank,EPT24811,,,ME49,pdh-e1alpha,chromosome XII,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,pyruvate dehydrogenase E1 component subunit alpha,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32341123,PubMed,10.1074/jbc.RA120.013004,J Biol Chem. 2020 May 29;295(22):7743-7752,Gupta.Nishith@hu-berlin.de,"All mutants were fully viable in prolonged cultures, albeit with impaired growth and concurrent loss of the apicoplast and displayed normal virulence in mice.",X Liang 2020,2020,4 genes,Liang-2020-Acquisition of exogenous fatty acid,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18507,PHI:11456,UniProt,S8GMY7,GenBank,EPT29904,,,ME49,pdh-e2,chromosome VIIa,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32341123,PubMed,10.1074/jbc.RA120.013004,J Biol Chem. 2020 May 29;295(22):7743-7752,Gupta.Nishith@hu-berlin.de,"All mutants were fully viable in prolonged cultures, albeit with impaired growth and concurrent loss of the apicoplast and displayed normal virulence in mice.",X Liang 2020,2020,4 genes,Liang-2020-Acquisition of exogenous fatty acid,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18508,PHI:11457,UniProt,S8GG49,GenBank,EPT27429,,,ME49,pdh-e3-I,chromosome IX,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,pyruvate dehydrogenase complex subunit,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32341123,PubMed,10.1074/jbc.RA120.013004,J Biol Chem. 2020 May 29;295(22):7743-7752,Gupta.Nishith@hu-berlin.de,"All mutants were fully viable in prolonged cultures, albeit with impaired growth and concurrent loss of the apicoplast and displayed normal virulence in mice.",X Liang 2020,2020,4 genes,Liang-2020-Acquisition of exogenous fatty acid,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18509,PHI:11458,UniProt,A0A7J6K108,GenBank,KAF4640639,,,RH-88,fabD,chromosome X,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,acyl transferase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32341123,PubMed,10.1074/jbc.RA120.013004,J Biol Chem. 2020 May 29;295(22):7743-7752,Gupta.Nishith@hu-berlin.de,"All mutants were fully viable in prolonged cultures, albeit with impaired growth and concurrent loss of the apicoplast and displayed normal virulence in mice.",X Liang 2020,2020,4 genes,Liang-2020-Acquisition of exogenous fatty acid,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18510,PHI:11459,UniProt,A0KL98,GenBank,ABK38597,,,ATCC 7966,alr-2,,,,,,,644,Aeromonas hydrophila,,HBNUAh01,diarrhea; nausea; vomiting,bony fishes,7962,Cyprinus carpio (related: common carp),,,,abdomen,alanine racemase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30940083,PubMed,10.1186/s12866-019-1437-3,BMC Microbiol. 2019 Apr 2;19(1):72,baohua519@126.com,A.H. Δalr significantly increased phagocytosis by macrophages of the mice and fish. Tissue: abdominal cavity,D Liu 2019,2019,1 gene,Liu-2019-Knockout of alanine racemase gene att,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18511,PHI:11459,UniProt,A0KL98,GenBank,ABK38597,,,ATCC 7966,alr-2,,,,,,,644,Aeromonas hydrophila,,HBNUAh01,diarrhea; nausea; vomiting,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; kidney; spleen; blood; macrophage,alanine racemase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30940083,PubMed,10.1186/s12866-019-1437-3,BMC Microbiol. 2019 Apr 2;19(1):72,baohua519@126.com,A.H. Δalr significantly increased phagocytosis by macrophages of the mice and fish.,D Liu 2019,2019,1 gene,Liu-2019-Knockout of alanine racemase gene att,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18512,PHI:11460,,no data found,GenBank,WP_000661406,,,,xtgS,,,,,,,1311,Streptococcus agalactiae,,GD201008-001,pneumonia; meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32690636,PubMed,10.1128/IAI.00035-20,Infect Immun. 2020 Sep 18;88(10):e00035-20,liugj100@njau.edu.cn,"XtgS inactivation significantly increased bacterial survival in host blood and animal challenge test, suggesting that it is a negative regulator of GBS pathogenicity.",G Liu 2020,2020,1 gene,Liu-2020-A novel streptococcal transcriptional,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18513,PHI:11460,,no data found,GenBank,WP_000661406,,,,xtgS,,,,,,,1311,Streptococcus agalactiae,,GD201008-001,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32690636,PubMed,10.1128/IAI.00035-20,Infect Immun. 2020 Sep 18;88(10):e00035-20,liugj100@njau.edu.cn,"XtgS inactivation significantly increased bacterial survival in host blood and animal challenge test, suggesting that it is a negative regulator of GBS pathogenicity.",G Liu 2020,2020,1 gene,Liu-2020-A novel streptococcal transcriptional,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18514,PHI:11460,,no data found,GenBank,WP_000661406,,,,xtgS,,,,,,,1311,Streptococcus agalactiae,,GD201008-001,pneumonia; meningitis,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,blood,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32690636,PubMed,10.1128/IAI.00035-20,Infect Immun. 2020 Sep 18;88(10):e00035-20,liugj100@njau.edu.cn,"XtgS inactivation significantly increased bacterial survival in host blood and animal challenge test, suggesting that it is a negative regulator of GBS pathogenicity.",G Liu 2020,2020,1 gene,Liu-2020-A novel streptococcal transcriptional,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18515,PHI:11461,UniProt,A0A0D2XG21,GenBank,KNA98528,,,4287,mt1 (FOXG_02862),chromosome 8,,,,,,5507,Fusarium oxysporum,426428,4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,root,metallothionein,,,,unaffected pathogenicity,,,,,,,,,,no,CdCl2; Zn(O2CCH3)2; ZnCl2; CuSO4,"CdCl2: CHEBI:35456, 2; Zn(O2CCH3): CHEBI:62984; ZnCl2: CHEBI:49976; CuSO4: CHEBI:23414",,,,,gene deletion: full; gene complementation,,,YVS,31134239,PubMed,10.1039/c9mt00081j,Metallomics. 2019 Jul 17;11(7):1230-1240,javier.capilla@urv.cat,Mt1 was dispensable for virulence in both mice and plant hosts but contributed to resistance to macrophage killing.,D Lorenzo-Gutierrez 2019,2019,1 gene,Lorenzo-Gutierr-2019-Role of the Fusarium oxys,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18516,PHI:11461,UniProt,A0A0D2XG21,GenBank,KNA98528,,,4287,mt1 (FOXG_02862),chromosome 8,,,,,,5507,Fusarium oxysporum,426428,4287,Fusarium wilt,rodents,10090,Mus musculus (related: house mouse),OF1,,,lung; kidney,metallothionein,,,,unaffected pathogenicity,,,,,,,,,,no,CdCl2; Zn(O2CCH3)2; ZnCl2; CuSO4,"CdCl2: CHEBI:35456, 2; Zn(O2CCH3): CHEBI:62984; ZnCl2: CHEBI:49976; CuSO4: CHEBI:23414",,,,,gene deletion: full; gene complementation,,,YVS,31134239,PubMed,10.1039/c9mt00081j,Metallomics. 2019 Jul 17;11(7):1230-1240,javier.capilla@urv.cat,Mt1 was dispensable for virulence in both mice and plant hosts but contributed to resistance to macrophage killing.,D Lorenzo-Gutierrez 2019,2019,1 gene,Lorenzo-Gutierr-2019-Role of the Fusarium oxys,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18517,PHI:11461,UniProt,A0A0D2XG21,GenBank,KNA98528,,,4287,mt1 (FOXG_02862),chromosome 8,,,,,,5507,Fusarium oxysporum,426428,4287,Fusarium wilt,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,J-774 cell,metallothionein,,,,reduced virulence,,,,,,,,,,no,CdCl2; Zn(O2CCH3)2; ZnCl2; CuSO4,"CdCl2: CHEBI:35456, 2; Zn(O2CCH3): CHEBI:62984; ZnCl2: CHEBI:49976; CuSO4: CHEBI:23414",,,,,gene deletion: full; gene complementation,,,YVS,31134239,PubMed,10.1039/c9mt00081j,Metallomics. 2019 Jul 17;11(7):1230-1240,javier.capilla@urv.cat,Mt1 was dispensable for virulence in both mice and plant hosts but contributed to resistance to macrophage killing.,D Lorenzo-Gutierrez 2019,2019,1 gene,Lorenzo-Gutierr-2019-Role of the Fusarium oxys,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18518,PHI:11462,UniProt,A0A454APR1,GenBank,ADR25057,,,PG45,mnuA (MBOVPG45_0215),,,,,,,28903,Mycoplasmopsis bovis,289397,PG45,,even-toed ungulates,9913,Bos taurus (related: cattle),,,,neutrophil,major membrane nuclease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,29685215,PubMed,10.1016/j.vetmic.2018.03.002,Vet Microbiol. 2018 May;218:13-19,glenfb@unimelb.edu.au,"M. bovis induced NET formation in bovine neutrophils, but that the major membrane nuclease MnuA was able to rapidly degrade NETs, and thus played a significant role in virulence.",F Mitiku 2018,2018,1 gene,Mitiku-2018-The major membrane nuclease MnuA d,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18519,PHI:11463,UniProt,Q9I5X1,GenBank,AE004492_13,,,PAO1,rcsA (PA0565),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),,,,,alkyl hydroperoxidase D-like protein,,,,reduced virulence,,,,,,,,,,no,HOCl; sodium hypochlorite (NaOCl); Ca(OCl)2; N-chlorotaurine; trichloroacetic acid; hydrogen peroxide; cumene hydroperoxide; tert-butylhydroperoxide; paraquat: ; plumbagin; menadione; diamide; N-ethylmaleimide; methylglyoxal; peroxynitrite,"HOCl: CHEBI:24757; sodium hypochlorite (NaOCl): CHEBI:32146, 2; Ca(OCl): CHEBI:31342; N-chlorotaurine: CAS:51036-13-6; trichloroacetic acid: CHEBI:30956; hydrogen peroxide: CHEBI:16240; cumene hydroperoxide: CHEBI:78673; tert-butylhydroperoxide: CHEBI:64090; paraquat: CHEBI:34905; plumbagin: CHEBI:8273; menadione: CHEBI:28869; diamide: CHEBI:48958; N-ethylmaleimide: CHEBI:44485; methylglyoxal: CHEBI:17158; peroxynitrite: CHEBI:25941",,,,,gene deletion: full; gene complementation,,,YVS,32801171,PubMed,10.1128/AEM.01480-20,Appl Environ Microbiol. 2020 Oct 1;86(20):e01480-20,skorn@cri.or.th,The pathogenicity of the rcsA mutant decreased dramatically in both Caenorhabditis elegans and Drosophila melanogaster host model systems compared to the wild type.,B Nontaleerak 2020,2020,1 gene,Nontaleerak-2020-Roles of the AhpD-family prot,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18520,PHI:11463,UniProt,Q9I5X1,GenBank,AE004492_13,,,PAO1,rcsA (PA0565),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,alkyl hydroperoxidase D-like protein,,,,reduced virulence,,,,,,,,,,no,HOCl; sodium hypochlorite (NaOCl); Ca(OCl)2; N-chlorotaurine; trichloroacetic acid; hydrogen peroxide; cumene hydroperoxide; tert-butylhydroperoxide; paraquat: ; plumbagin; menadione; diamide; N-ethylmaleimide; methylglyoxal; peroxynitrite,"HOCl: CHEBI:24757; sodium hypochlorite (NaOCl): CHEBI:32146, 2; Ca(OCl): CHEBI:31342; N-chlorotaurine: CAS:51036-13-6; trichloroacetic acid: CHEBI:30956; hydrogen peroxide: CHEBI:16240; cumene hydroperoxide: CHEBI:78673; tert-butylhydroperoxide: CHEBI:64090; paraquat: CHEBI:34905; plumbagin: CHEBI:8273; menadione: CHEBI:28869; diamide: CHEBI:48958; N-ethylmaleimide: CHEBI:44485; methylglyoxal: CHEBI:17158; peroxynitrite: CHEBI:25941",,,,,gene deletion: full; gene complementation,,,YVS,32801171,PubMed,10.1128/AEM.01480-20,Appl Environ Microbiol. 2020 Oct 1;86(20):e01480-20,skorn@cri.or.th,The pathogenicity of the rcsA mutant decreased dramatically in both Caenorhabditis elegans and Drosophila melanogaster host model systems compared to the wild type.,B Nontaleerak 2020,2020,1 gene,Nontaleerak-2020-Roles of the AhpD-family prot,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18521,PHI:11464,UniProt,D2TT81,GenBank,CBG89139,,,ICC168,eutR,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon,ethanolamine-sensing transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32631916,PubMed,10.1128/IAI.00137-20,Infect Immun. 2020 Aug 19;88(9):e00137-20,melissakendall@virginia.edu,EutR was required for maximal C. rodentium fitness in the intestinal tract.,C A Rowley 2020,2020,1 gene,Rowley-2020-The Ethanolamine-Sensing Transcrip,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18522,PHI:11465,,no data found,,,,,,PPHD,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"prolyl hydroxylase, putative bacterial oxygen sensor",,,,increased virulence (hypervirulence),,,,,,,,,,no,tetracycline; doxycycline; minocycline; tigecycline,tetracycline: CHEBI:27902; doxycycline: CHEBI:50845; minocycline: CHEBI:50694; tigecycline: CHEBI:149836,,,,,gene deletion: full,,,YVS,31826919,PubMed,10.1074/jbc.RA119.010033,J Biol Chem. 2020 Jan 31;295(5):1195-1201,cormac.taylor@ucd.ie,P. aeruginosa strain lacking PPHD (PAO310) exhibited increased virulence associated with increased bacterial motility.,B Schaible 2020,2020,1 gene,Schaible-2020-The putative bacterial oxygen se,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18523,PHI:11466,UniProt,A0A0D6G9U1,GenBank,AGP27452,,,Bmb9393,ndhF,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen; heart,NADH dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32202364,PubMed,10.15252/embr.201845832,EMBO Rep. 2020 May 6;21(5):e45832,lschurig@illinois.edu,"Lack of two type-2 respiratory NADH dehydrogenases (NDH-2s) eliminated biofilm formation, production of alpha-toxin, and reduced the ability to colonize specific organs in a mouse model of systemic infection.",L A Schurig-Briccio 2020,2020,2 genes,Schurig-Briccio-2020-Role of respiratory NADH,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18524,PHI:11467,,no data found,GenBank,GBT68139,,,M6KS0526_2,ndhC,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen; heart,NAD(P)H-quinone oxidoreductase subunit 3,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32202364,PubMed,10.15252/embr.201845832,EMBO Rep. 2020 May 6;21(5):e45832,lschurig@illinois.edu,"Lack of two type-2 respiratory NADH dehydrogenases (NDH-2s) eliminated biofilm formation, production of alpha-toxin, and reduced the ability to colonize specific organs in a mouse model of systemic infection.",L A Schurig-Briccio 2020,2020,2 genes,Schurig-Briccio-2020-Role of respiratory NADH,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18525,PHI:11466,UniProt,A0A0D6G9U1,GenBank,AGP27452,,,Bmb9393,ndhF,,,,,,PHI:11467,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen; kidney; heart,NADH dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32202364,PubMed,10.15252/embr.201845832,EMBO Rep. 2020 May 6;21(5):e45832,lschurig@illinois.edu,"Lack of two type-2 respiratory NADH dehydrogenases (NDH-2s) eliminated biofilm formation, production of alpha-toxin, and reduced the ability to colonize specific organs in a mouse model of systemic infection.",L A Schurig-Briccio 2020,2020,2 genes,Schurig-Briccio-2020-Role of respiratory NADH,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18526,PHI:11467,,no data found,GenBank,GBT68139,,,M6KS0526_2,ndhC,,,,,,PHI:11466,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen; kidney; heart,NAD(P)H-quinone oxidoreductase subunit 3,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32202364,PubMed,10.15252/embr.201845832,EMBO Rep. 2020 May 6;21(5):e45832,lschurig@illinois.edu,"Lack of two type-2 respiratory NADH dehydrogenases (NDH-2s) eliminated biofilm formation, production of alpha-toxin, and reduced the ability to colonize specific organs in a mouse model of systemic infection.",L A Schurig-Briccio 2020,2020,2 genes,Schurig-Briccio-2020-Role of respiratory NADH,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18527,PHI:11466,UniProt,A0A0D6G9U1,GenBank,AGP27452,,,Bmb9393,ndhF,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,NADH dehydrogenase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32202364,PubMed,10.15252/embr.201845832,EMBO Rep. 2020 May 6;21(5):e45832,lschurig@illinois.edu,"Lack of two type-2 respiratory NADH dehydrogenases (NDH-2s) eliminated biofilm formation, production of alpha-toxin, and reduced the ability to colonize specific organs in a mouse model of systemic infection.",L A Schurig-Briccio 2020,2020,2 genes,Schurig-Briccio-2020-Role of respiratory NADH,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18528,PHI:11467,,no data found,GenBank,GBT68139,,,M6KS0526_2,ndhC,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),CD-1,,,kidney,NAD(P)H-quinone oxidoreductase subunit 3,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32202364,PubMed,10.15252/embr.201845832,EMBO Rep. 2020 May 6;21(5):e45832,lschurig@illinois.edu,"Lack of two type-2 respiratory NADH dehydrogenases (NDH-2s) eliminated biofilm formation, production of alpha-toxin, and reduced the ability to colonize specific organs in a mouse model of systemic infection.",L A Schurig-Briccio 2020,2020,2 genes,Schurig-Briccio-2020-Role of respiratory NADH,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18529,PHI:11468,UniProt,A0A0H2ZPW2,GenBank,ABJ54781,,,D39,SPD_1366 (CvfD),,,,,,,1313,Streptococcus pneumoniae,373153,D39,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,conserved virulence factor D,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32601068,PubMed,10.1128/JB.00245-20,J Bacteriol. 2020 Aug 25;202(18):e00245-20,winklerm@indiana.edu,Loss of the CvfD protein resulted in attenuation of virulence in a murine pneumonia model.,D Sinha 2020,2020,1 gene,Sinha-2020-S1 Domain RNA-Binding Protein CvfD,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18530,PHI:11469,UniProt,A0A1D8PE76,GenBank,AOW26437,,,SC5314,Ire1,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,non-specific serine/threonine protein kinase,,,,reduced virulence,,,,,,,,,,no,tunicamycin; SDS; amphotericin B; fluconazole; DTT; congo red; calcofluor white; caspofungin; ketoconazole; voriconazole; 2-mercaptoethanol,tunicamycin: CHEBI:29699; SDS: CHEBI:8984; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; dithiothreitol: CHEBI:18320; congo red: CHEBI:34653; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; ketoconazole: CHEBI:48336; voriconazole: CHEBI:10023; 2-mercaptoethanol: CHEBI:41218,,,,,gene deletion: full; gene complementation,,,YVS,33403715,PubMed,10.1111/cmi.13307,Cell Microbiol. 2021 May;23(5):e13307,sneh@mail.jnu.ac.in,Ire1-mutant strain was severely defective in hyphal morphogenesis and biofilm formation as well as in establishing a successful infection in vivo.,S Sircaik 2021,2021,1 gene,Sircaik-2021-The protein kinase Ire1 impacts p,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18531,PHI:11470,UniProt,A0A0F6B629,GenBank,ACY89976,,,14028S,STM14_3563,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,putative transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31832871,PubMed,10.1007/s10123-019-00110-3,Int Microbiol. 2020 Aug;23(3):381-390,jianglingyan@nankai.edu.cn,S. Typhimurium showed reduced growth in murine macrophages and attenuated virulence in mice owing to deletion of STM14_3563 gene.,X Song 2019,2019,1 gene,Song-2019-The putative transcriptional regulat,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18532,PHI:11470,UniProt,A0A0F6B629,GenBank,ACY89976,,,14028S,STM14_3563,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,putative transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31832871,PubMed,10.1007/s10123-019-00110-3,Int Microbiol. 2020 Aug;23(3):381-390,jianglingyan@nankai.edu.cn,S. Typhimurium showed reduced growth in murine macrophages and attenuated virulence in mice owing to deletion of STM14_3563 gene.,X Song 2019,2019,1 gene,Song-2019-The putative transcriptional regulat,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18533,PHI:11471,UniProt,Q6FMW8,GenBank,CAG61387,,,CBS 138,VHT1 (CAGL0K04609g),chromosome K,,,,,,5478,Candida glabrata,,ATCC 2001,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,brain,biotin transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32083801,PubMed,10.1111/cmi.13197,Cell Microbiol. 2020 Jul;22(7):e13197,bernhard.hube@leibniz-hki.de,The lack of VHT1 led to reduced fungal burden in C. glabrata-infected brains and C. albicans-infected brains and kidneys.,M Sprenger 2020,2020,4 genes,Sprenger-2020-Fungal biotin homeostasis is ess,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18534,PHI:11471,UniProt,Q6FMW8,GenBank,CAG61387,,,CBS 138,VHT1 (CAGL0K04609g),chromosome K,,,,,,5478,Candida glabrata,,ATCC 2001,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver; kidney,biotin transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32083801,PubMed,10.1111/cmi.13197,Cell Microbiol. 2020 Jul;22(7):e13197,bernhard.hube@leibniz-hki.de,The lack of VHT1 led to reduced fungal burden in C. glabrata-infected brains and C. albicans-infected brains and kidneys.,M Sprenger 2020,2020,4 genes,Sprenger-2020-Fungal biotin homeostasis is ess,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18535,PHI:11472,UniProt,A0A7G7JNY8,GenBank,QNG17253,,,BG2,VHR1 (CAGL0M12496g),chromosome M,,,,,,5478,Candida glabrata,,ATCC 2001,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,brain; kidney; spleen; liver,biotin transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32083801,PubMed,10.1111/cmi.13197,Cell Microbiol. 2020 Jul;22(7):e13197,bernhard.hube@leibniz-hki.de,The lack of VHT1 led to reduced fungal burden in C. glabrata-infected brains and C. albicans-infected brains and kidneys.,M Sprenger 2020,2020,4 genes,Sprenger-2020-Fungal biotin homeostasis is ess,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18536,PHI:11471,UniProt,Q6FMW8,GenBank,CAG61387,,,CBS 138,VHT1 (CAGL0K04609g),chromosome K,,,,,,5478,Candida glabrata,,ATCC 2001,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,macrophage,biotin transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32083801,PubMed,10.1111/cmi.13197,Cell Microbiol. 2020 Jul;22(7):e13197,bernhard.hube@leibniz-hki.de,The lack of VHT1 led to reduced fungal burden in C. glabrata-infected brains and C. albicans-infected brains and kidneys.,M Sprenger 2020,2020,4 genes,Sprenger-2020-Fungal biotin homeostasis is ess,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18537,PHI:11472,UniProt,A0A7G7JNY8,GenBank,QNG17253,,,BG2,VHR1 (CAGL0M12496g),chromosome M,,,,,,5478,Candida glabrata,,ATCC 2001,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,macrophage,biotin transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32083801,PubMed,10.1111/cmi.13197,Cell Microbiol. 2020 Jul;22(7):e13197,bernhard.hube@leibniz-hki.de,The lack of VHT1 led to reduced fungal burden in C. glabrata-infected brains and C. albicans-infected brains and kidneys.,M Sprenger 2020,2020,4 genes,Sprenger-2020-Fungal biotin homeostasis is ess,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18538,PHI:11473,UniProt,A0A1D8PSE5,GenBank,AOW31065,,,SC5314,VHT1 (CR_03270W),chromosome R,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,macrophage,biotin transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32083801,PubMed,10.1111/cmi.13197,Cell Microbiol. 2020 Jul;22(7):e13197,bernhard.hube@leibniz-hki.de,The lack of VHT1 led to reduced fungal burden in C. glabrata-infected brains and C. albicans-infected brains and kidneys.,M Sprenger 2020,2020,4 genes,Sprenger-2020-Fungal biotin homeostasis is ess,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18539,PHI:11474,UniProt,A0A1D8PRT2,GenBank,AOW30831,,,SC5314,VHR1 (CR_00630W),chromosome R,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,primates,9606,Homo sapiens (related: human),,,,macrophage,biotin transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32083801,PubMed,10.1111/cmi.13197,Cell Microbiol. 2020 Jul;22(7):e13197,bernhard.hube@leibniz-hki.de,The lack of VHT1 led to reduced fungal burden in C. glabrata-infected brains and C. albicans-infected brains and kidneys.,M Sprenger 2020,2020,4 genes,Sprenger-2020-Fungal biotin homeostasis is ess,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18540,PHI:11473,UniProt,A0A1D8PSE5,GenBank,AOW31065,,,SC5314,VHT1 (CR_03270W),chromosome R,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; kidney,biotin transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32083801,PubMed,10.1111/cmi.13197,Cell Microbiol. 2020 Jul;22(7):e13197,bernhard.hube@leibniz-hki.de,The lack of VHT1 led to reduced fungal burden in C. glabrata-infected brains and C. albicans-infected brains and kidneys.,M Sprenger 2020,2020,4 genes,Sprenger-2020-Fungal biotin homeostasis is ess,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18541,PHI:11473,UniProt,A0A1D8PSE5,GenBank,AOW31065,,,SC5314,VHT1 (CR_03270W),chromosome R,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,biotin transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32083801,PubMed,10.1111/cmi.13197,Cell Microbiol. 2020 Jul;22(7):e13197,bernhard.hube@leibniz-hki.de,The lack of VHT1 led to reduced fungal burden in C. glabrata-infected brains and C. albicans-infected brains and kidneys.,M Sprenger 2020,2020,4 genes,Sprenger-2020-Fungal biotin homeostasis is ess,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18542,PHI:11474,UniProt,A0A1D8PRT2,GenBank,AOW30831,,,SC5314,VHR1 (CR_00630W),chromosome R,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; kidney,biotin transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32083801,PubMed,10.1111/cmi.13197,Cell Microbiol. 2020 Jul;22(7):e13197,bernhard.hube@leibniz-hki.de,The lack of VHT1 led to reduced fungal burden in C. glabrata-infected brains and C. albicans-infected brains and kidneys.,M Sprenger 2020,2020,4 genes,Sprenger-2020-Fungal biotin homeostasis is ess,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18543,PHI:11475,UniProt,A0A0D1DX64,GenBank,KIS68804,,,521,UMAG_12226 (sta1),chromosome 8,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32112567,PubMed,10.1111/nph.16508,New Phytol. 2020 Jul;227(1):185-199,kahmann@mpi-marburg.mpg.de,Constitutive or delayed expression of sta1 during plant colonization negatively impacted virulence.,S Tanaka 2020,2020,1 gene,Tanaka-2020-The functionally conserved effecto,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18544,PHI:11476,UniProt,A0A6G1NSL2,GenBank,KAF3356274,,,VDG1,atf1,,,,,,,27337,Verticillium dahliae,498257,XS11,vascular wilt,eudicots,292731,Cotinus obovatus (no common name found),,,,seedling,bZip transcription factor,,,,reduced virulence,,yes,,,,,,,,no,NO; H2O2,NO: CHEBI:16480; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32040203,PubMed,10.1111/nph.16481,New Phytol. 2020 Jun;226(5):1461-1479,ylwang@bjfu.edu.cn,VdAtf1 controled pathogenesis via the regulation of nitric oxide (NO) resistance and inorganic nitrogen metabolism rather than oxidative resistance and was important for penetration peg formation in V. dahliae.,C Tang 2020,2020,1 gene,Tang-2020-The bZIP transcription factor VdAtf1,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18545,PHI:11476,UniProt,A0A6G1NSL2,GenBank,KAF3356274,,,VDG1,atf1,,,,,,,27337,Verticillium dahliae,498257,XS11,vascular wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,seedling,bZip transcription factor,,,,reduced virulence,,yes,,,,,,,,no,NO; H2O2,NO: CHEBI:16480; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32040203,PubMed,10.1111/nph.16481,New Phytol. 2020 Jun;226(5):1461-1479,ylwang@bjfu.edu.cn,VdAtf1 controled pathogenesis via the regulation of nitric oxide (NO) resistance and inorganic nitrogen metabolism rather than oxidative resistance and was important for penetration peg formation in V. dahliae.,C Tang 2020,2020,1 gene,Tang-2020-The bZIP transcription factor VdAtf1,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18546,PHI:11477,UniProt,Q59185,GenBank,AAB91493,,,B31,lon-1 (BB0253),,lon-1 (S714A),,,,,139,Borreliella burgdorferi,,CE162,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin; joint; heart,ATP-dependent protease,,,,reduced virulence,,,,,,,,,,no,NaCl; tert-butylhydroperoxide,NaCl: CHEBI:26710; tert-butylhydroperoxide: CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,32205400,PubMed,10.1128/IAI.00951-19,Infect Immun. 2020 May 20;88(6):e00951-19,zouyang@usf.edu,"A lon-1(S714A) mutant failed to infect mice, suggesting that the proteolytic activity of Lon-1 was essential for bacterial infection.",C Thompson 2020,2020,1 gene,Thompson-2020-The Lon-1 Protease Is Required b,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18547,PHI:11478,UniProt,S7V482,GenBank,EPR64741,,,GT1,mag1,,,,,,,5811,Toxoplasma gondii,383379,type II strain Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; bone marrow-derived macrophage,dense granular protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34006649,PubMed,10.1128/mBio.00603-21,mBio. 2021 May 18;12(3):e00603-21,tadakimi.tomita@einsteinmed.org,"Infection of BMDM with Δmag1 parasites induced a significant increase in interleukin 1-beta secretion, which is a hallmark of inflammasome activation.",T Tomita 2021,2021,1 gene,Tomita-2021-Toxoplasma gondii Matrix Antigen 1,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18548,PHI:11479,UniProt,Q99WG6,GenBank,BAB56598,,,Mu50,Lpl1,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,lipoprotein-like lipoprotein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: synthetic peptide,,,YVS,31515903,PubMed,10.1111/cmi.13111,Cell Microbiol. 2020 Jan;22(1):e13111,friedrich.goetz@uni-tuebingen.de,Synthetic peptides covering the Lpl1 sequence caused a twofold to fivefold increase of S. aureus invasion in HaCaT cells.,P M Tribelli 2019,2019,1 gene,Tribelli-2019-Staphylococcus aureus Lpl protei,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18549,PHI:11480,,no data found,,,,,,saxA,,,,,,,78398,Pectobacterium odoriferum,,NCPPB 3841,soft rot (potato); blackleg disease (potato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,isothiocyanate hydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31872947,PubMed,10.1111/mpp.12900,Mol Plant Pathol. 2020 Mar;21(3):349-359,c.welte@science.ru.nl,Deletion of saxA genes representing two of the most common classes from P. odoriferum and P. versatile resulted in significantly reduced virulence on Arabidopsis thaliana and Brassica oleracea.,T J M van den Bosch 2019,2019,2 genes,van den Bosch-2019-Single gene enables plant p,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18550,PHI:11481,,no data found,,,,,,saxA,,,,,,,2488639,Pectobacterium versatile,,SCC1,soft rot (potato); blackleg disease (potato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,isothiocyanate hydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31872947,PubMed,10.1111/mpp.12900,Mol Plant Pathol. 2020 Mar;21(3):349-359,c.welte@science.ru.nl,Deletion of saxA genes representing two of the most common classes from P. odoriferum and P. versatile resulted in significantly reduced virulence on Arabidopsis thaliana and Brassica oleracea.,T J M van den Bosch 2019,2019,2 genes,van den Bosch-2019-Single gene enables plant p,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18551,PHI:11480,,no data found,,,,,,saxA,,,,,,,78398,Pectobacterium odoriferum,,NCPPB 3841,soft rot (potato); blackleg disease (potato),eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,isothiocyanate hydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31872947,PubMed,10.1111/mpp.12900,Mol Plant Pathol. 2020 Mar;21(3):349-359,c.welte@science.ru.nl,Deletion of saxA genes representing two of the most common classes from P. odoriferum and P. versatile resulted in significantly reduced virulence on Arabidopsis thaliana and Brassica oleracea.,T J M van den Bosch 2019,2019,2 genes,van den Bosch-2019-Single gene enables plant p,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18552,PHI:11481,,no data found,,,,,,saxA,,,,,,,2488639,Pectobacterium versatile,,SCC1,soft rot (potato); blackleg disease (potato),eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,isothiocyanate hydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31872947,PubMed,10.1111/mpp.12900,Mol Plant Pathol. 2020 Mar;21(3):349-359,c.welte@science.ru.nl,Deletion of saxA genes representing two of the most common classes from P. odoriferum and P. versatile resulted in significantly reduced virulence on Arabidopsis thaliana and Brassica oleracea.,T J M van den Bosch 2019,2019,2 genes,van den Bosch-2019-Single gene enables plant p,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18553,PHI:11482,,no data found,,,,,,pmrA (FTL_0552),,,,,,,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),J774.1 cell line,,,macrophage,orphan response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32839173,PubMed,10.1128/JB.00321-20,J Bacteriol. 2020 Oct 8;202(21):e00321-20,john.gunn@nationwidechildrens.org,"PmrA was responsible for intramacrophage growth and virulence; PmrA repressed the expression of priM, described to encode an antivirulence determinant.",K V Hoang 2020,2020,2 genes,Van Hoang-2020-The sensor kinase QseC regulate,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18554,PHI:11483,,no data found,,,,,,priM,,,,,,,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),J774.1 cell line,,,macrophage,antivirulence determinant,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32839173,PubMed,10.1128/JB.00321-20,J Bacteriol. 2020 Oct 8;202(21):e00321-20,john.gunn@nationwidechildrens.org,"PmrA was responsible for intramacrophage growth and virulence; PmrA repressed the expression of priM, described to encode an antivirulence determinant.",K V Hoang 2020,2020,2 genes,Van Hoang-2020-The sensor kinase QseC regulate,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18555,PHI:11482,,no data found,,,,,,pmrA (FTL_0552),,,,,,PHI:11483,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),J774.1 cell line,,,macrophage,orphan response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32839173,PubMed,10.1128/JB.00321-20,J Bacteriol. 2020 Oct 8;202(21):e00321-20,john.gunn@nationwidechildrens.org,"PmrA was responsible for intramacrophage growth and virulence; PmrA repressed the expression of priM, described to encode an antivirulence determinant.",K V Hoang 2020,2020,2 genes,Van Hoang-2020-The sensor kinase QseC regulate,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18556,PHI:11483,,no data found,,,,,,priM,,,,,,PHI:11482,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),J774.1 cell line,,,macrophage,antivirulence determinant,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,32839173,PubMed,10.1128/JB.00321-20,J Bacteriol. 2020 Oct 8;202(21):e00321-20,john.gunn@nationwidechildrens.org,"PmrA was responsible for intramacrophage growth and virulence; PmrA repressed the expression of priM, described to encode an antivirulence determinant.",K V Hoang 2020,2020,2 genes,Van Hoang-2020-The sensor kinase QseC regulate,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18557,PHI:11484,UniProt,Q8DXM9,GenBank,AE014274_14,,,2603V/R,gshAB (SAG_1821),,,,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood,glutathione biosynthesis bifunctional protein,,,,reduced virulence,,,,,,,,,,no,H2O2; HOCl; erythromycin,H2O2: CHEBI:16240; HOCl: CHEBI:24757; erythromycin: CHEBI:48923,,,,,gene deletion: full; gene complementation,,,YVS,31331978,PubMed,10.1128/JB.00367-19,J Bacteriol. 2019 Sep 20;201(20):e00367-19,blythe.janowiakmulligan@slu.edu,Deletion of gshAB in S. agalactiae strain COH1 significantly attenuated virulence compared to the wild-type or gshAB knock-in strains in a mouse model of sepsis.,E A Walker 2019,2019,1 gene,Walker-2019-Glutathione Synthesis Contributes,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18558,PHI:11485,UniProt,B5TSF4,GenBank,ACH87600,,,RH,GRA12,chromosome IX,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6; Kunming,,,brain,dense granular protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31908049,PubMed,10.1096/fj.201901416RR,FASEB J. 2020 Feb;34(2):3165-3178,wangjinlei90@126.com,Functional association between GRA12 and ROP18 was revealed by the severe attenuation of virulence in a double mutant relative to the single individual mutations.,J L Wang 2020,2020,2 genes,Wang-2020-Novel roles of dense granule protein,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18559,PHI:11486,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,ROP18,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6; Kunming,,,brain,rhoptry kinase family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31908049,PubMed,10.1096/fj.201901416RR,FASEB J. 2020 Feb;34(2):3165-3178,wangjinlei90@126.com,Functional association between GRA12 and ROP18 was revealed by the severe attenuation of virulence in a double mutant relative to the single individual mutations.,J L Wang 2020,2020,2 genes,Wang-2020-Novel roles of dense granule protein,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18560,PHI:11485,UniProt,B5TSF4,GenBank,ACH87600,,,RH,GRA12,chromosome IX,,,,,PHI:11486,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6; Kunming,,,brain,dense granular protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31908049,PubMed,10.1096/fj.201901416RR,FASEB J. 2020 Feb;34(2):3165-3178,wangjinlei90@126.com,Functional association between GRA12 and ROP18 was revealed by the severe attenuation of virulence in a double mutant relative to the single individual mutations.,J L Wang 2020,2020,2 genes,Wang-2020-Novel roles of dense granule protein,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18561,PHI:11486,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,ROP18,,,,,,PHI:11485,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6; Kunming,,,brain,rhoptry kinase family protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31908049,PubMed,10.1096/fj.201901416RR,FASEB J. 2020 Feb;34(2):3165-3178,wangjinlei90@126.com,Functional association between GRA12 and ROP18 was revealed by the severe attenuation of virulence in a double mutant relative to the single individual mutations.,J L Wang 2020,2020,2 genes,Wang-2020-Novel roles of dense granule protein,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18562,PHI:11485,UniProt,B5TSF4,GenBank,ACH87600,,,RH,GRA12,chromosome IX,,,,,,5811,Toxoplasma gondii,383379,type II strain Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6; Kunming,,,brain,dense granular protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31908049,PubMed,10.1096/fj.201901416RR,FASEB J. 2020 Feb;34(2):3165-3178,wangjinlei90@126.com,Functional association between GRA12 and ROP18 was revealed by the severe attenuation of virulence in a double mutant relative to the single individual mutations.,J L Wang 2020,2020,2 genes,Wang-2020-Novel roles of dense granule protein,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18563,PHI:11486,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,ROP18,,,,,,,5811,Toxoplasma gondii,383379,type II strain Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6; Kunming,,,brain,rhoptry kinase family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31908049,PubMed,10.1096/fj.201901416RR,FASEB J. 2020 Feb;34(2):3165-3178,wangjinlei90@126.com,Functional association between GRA12 and ROP18 was revealed by the severe attenuation of virulence in a double mutant relative to the single individual mutations.,J L Wang 2020,2020,2 genes,Wang-2020-Novel roles of dense granule protein,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18564,PHI:11485,UniProt,B5TSF4,GenBank,ACH87600,,,RH,GRA12,chromosome IX,,,,,PHI:11486,5811,Toxoplasma gondii,383379,type II strain Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6; Kunming,,,brain,dense granular protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31908049,PubMed,10.1096/fj.201901416RR,FASEB J. 2020 Feb;34(2):3165-3178,wangjinlei90@126.com,Functional association between GRA12 and ROP18 was revealed by the severe attenuation of virulence in a double mutant relative to the single individual mutations.,J L Wang 2020,2020,2 genes,Wang-2020-Novel roles of dense granule protein,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18565,PHI:11486,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,ROP18,,,,,,PHI:11485,5811,Toxoplasma gondii,383379,type II strain Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6; Kunming,,,brain,rhoptry kinase family protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31908049,PubMed,10.1096/fj.201901416RR,FASEB J. 2020 Feb;34(2):3165-3178,wangjinlei90@126.com,Functional association between GRA12 and ROP18 was revealed by the severe attenuation of virulence in a double mutant relative to the single individual mutations.,J L Wang 2020,2020,2 genes,Wang-2020-Novel roles of dense granule protein,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18566,PHI:11485,UniProt,B5TSF4,GenBank,ACH87600,,,RH,GRA12,chromosome IX,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,dense granular protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31908049,PubMed,10.1096/fj.201901416RR,FASEB J. 2020 Feb;34(2):3165-3178,wangjinlei90@126.com,Deletion of GRA12 in type I RH and type II Pru T. gondii strains did not affect the parasite growth and replication in vitro.,J L Wang 2020,2020,2 genes,Wang-2020-Novel roles of dense granule protein,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18567,PHI:11485,UniProt,B5TSF4,GenBank,ACH87600,,,RH,GRA12,chromosome IX,,,,,,5811,Toxoplasma gondii,383379,type II strain Prugniaud,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,dense granular protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31908049,PubMed,10.1096/fj.201901416RR,FASEB J. 2020 Feb;34(2):3165-3178,wangjinlei90@126.com,Deletion of GRA12 in type I RH and type II Pru T. gondii strains did not affect the parasite growth and replication in vitro.,J L Wang 2020,2020,2 genes,Wang-2020-Novel roles of dense granule protein,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18568,PHI:11487,UniProt,Q8DQF1,GenBank,AAK99510,,,R6,pepN,,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; bronchoalveolar lavage fluid,aminopeptidase N,,,MAPK and PI3K/AKT signaling,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32103444,PubMed,10.1007/s12275-020-9538-0,J Microbiol. 2020 Apr;58(4):330-339,xuwen@cqmu.edu.cn,PepN was essential for the virulence of S. pneumoniae and induced host innate immunity via MAPK and PI3K/AKT signaling.,L Wang 2020,2020,1 gene,Wang-2020-Streptococcus pneumoniae aminopeptid,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18569,PHI:11487,UniProt,Q8DQF1,GenBank,AAK99510,,,R6,pepN,,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,peritoneal macrophage,aminopeptidase N,,,MAPK and PI3K/AKT signaling,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,32103444,PubMed,10.1007/s12275-020-9538-0,J Microbiol. 2020 Apr;58(4):330-339,xuwen@cqmu.edu.cn,PepN was essential for the virulence of S. pneumoniae and induced host innate immunity via MAPK and PI3K/AKT signaling.,L Wang 2020,2020,1 gene,Wang-2020-Streptococcus pneumoniae aminopeptid,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18570,PHI:11487,UniProt,Q8DQF1,GenBank,AAK99510,,,R6,pepN,,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal meningitis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,aminopeptidase N,,,MAPK and PI3K/AKT signaling,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32103444,PubMed,10.1007/s12275-020-9538-0,J Microbiol. 2020 Apr;58(4):330-339,xuwen@cqmu.edu.cn,PepN was essential for the virulence of S. pneumoniae and induced host innate immunity via MAPK and PI3K/AKT signaling.,L Wang 2020,2020,1 gene,Wang-2020-Streptococcus pneumoniae aminopeptid,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18571,PHI:11488,UniProt,A4VXU8,GenBank,ABP90937,,,05ZYH33,nrtR,,,,,,,1307,Streptococcus suis,391295,05ZYH33,septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,nudix-related transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30759348,PubMed,10.1096/fj.201802179RR,FASEB J. 2019 May;33(5):6055-6068,fengyj@zju.edu.cn,NrtR knockout in S. suis serotype 2 reduced its capacity to form biofilms and attenuated its virulence in a mouse infection model.,Q Wang 2019,2019,1 gene,"Wang-2019-Functional definition of NrtR, a rem",BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18572,PHI:11489,UniProt,A0A3T0ZYX7,GenBank,BBG85468,,,GSH8-2,icmF,,,,,,,644,Aeromonas hydrophila,,BB1,diarrhea; nausea; vomiting,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,macrophage,type VI secretion protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,30919989,PubMed,10.1111/jfd.12991,J Fish Dis. 2019 Jun;42(6):895-904,yxqin@jmu.edu.cn,"The intracellular survival rate of the wild-type strain was 92.3%, while the survival rate of icmF-RNAi was only 20.58%.",S Wang 2019,2019,1 gene,Wang-2019-The role and mechanism of icmF in Ae,BATCH_107A,2021-07-01,MC,,,,,,,,,,,,,
,,Record 18573,PHI:11490,UniProt,P9WNK7,GenBank,CCP46704,,,H37Rv,EsxA,,"T2A, T2R, T2Q, T2S",,EsxB,UniProt: P9WNK5; GenBank: CCP46703,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,6 kDa early secretory antigenic target,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; other evidence: heterologous expression,,,YVS,32169899,PubMed,10.1074/jbc.RA119.012497,J Biol Chem. 2020 Apr 24;295(17):5785-5794,jsun@utep.edu,The mutations without N-acetylation attenuated mycobacterial virulence and inhibited cytosolic translocation.,J Aguilera 2020,2020,1 gene,Aguilera-2020-N (a)-Acetylation of the virulen,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18574,PHI:11491,UniProt,Q48S41,GenBank,AAX72469,,,MGAS6180,rocA,,,,covS,UniProt: O87528; GenBank: ACE75887,,1314,Streptococcus pyogenes,,serotype M28 strain MGAS28426,pharyngitis; necrotizing fasciitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,hindlimb,sensory transduction protein kinase,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full,,,YVS,32817331,PubMed,10.1128/IAI.00386-20,Infect Immun. 2020 Oct 19;88(11):e00386-20,rjolsen@houstonmethodist.org,Single amino acid replacements along the entire length of RocA disrupt RocA-RocA and RocA-CovS interactions to significantly alter the GAS virulence phenotype as defined by secreted virulence factor activity in vitro and tissue destruction and mortality in vivo.,P E Bernard 2020,2020,1 gene,Bernard-2020-Single amino acid replacements in,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18575,PHI:11491,UniProt,Q48S41,GenBank,AAX72469,,,MGAS6180,rocA,,T442P and Q443,,covS,UniProt: O87528; GenBank: ACE75887,,1314,Streptococcus pyogenes,,serotype M28 strain MGAS28426,pharyngitis; necrotizing fasciitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,hindlimb,sensory transduction protein kinase,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene mutation,,,YVS,32817331,PubMed,10.1128/IAI.00386-20,Infect Immun. 2020 Oct 19;88(11):e00386-20,rjolsen@houstonmethodist.org,Single amino acid replacements along the entire length of RocA disrupt RocA-RocA and RocA-CovS interactions to significantly alter the GAS virulence phenotype as defined by secreted virulence factor activity in vitro and tissue destruction and mortality in vivo.,P E Bernard 2020,2020,1 gene,Bernard-2020-Single amino acid replacements in,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18576,PHI:11491,UniProt,Q48S41,GenBank,AAX72469,,,MGAS6180,rocA,,V420I and T442I,,covS,UniProt: O87528; GenBank: ACE75887,,1314,Streptococcus pyogenes,,serotype M28 strain MGAS28426,pharyngitis; necrotizing fasciitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,hindlimb,sensory transduction protein kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,32817331,PubMed,10.1128/IAI.00386-20,Infect Immun. 2020 Oct 19;88(11):e00386-20,rjolsen@houstonmethodist.org,Single amino acid replacements along the entire length of RocA disrupt RocA-RocA and RocA-CovS interactions to significantly alter the GAS virulence phenotype as defined by secreted virulence factor activity in vitro and tissue destruction and mortality in vivo.,P E Bernard 2020,2020,1 gene,Bernard-2020-Single amino acid replacements in,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18577,PHI:11492,UniProt,E9ESW5,GenBank,EFZ01780,,,ARSEF 23,ilvC (MAA_ 03009),,,,,,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"ketol-acid reductoisomerase, mitochondrial",,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,reduced,no,Congo red; SDS; H2O2; NaCl; menadione,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:26710; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,32769188,PubMed,10.1128/AEM.01682-20,Appl Environ Microbiol. 2020 Oct 1;86(20):e01682-20,bhuang@ahau.edu.cn,Germination defect caused complete failures of conidial penetration and pathogenicity in the ΔMrilvC mutant.,F Luo 2020,2020,1 gene,Luo-2020-The intermediates in branched-chain a,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18578,PHI:11493,UniProt,Q82Z99,GenBank,AAO82844,,,V583,rny (EF3170),,,,,,,1351,Enterococcus faecalis,,V19,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RNase Y,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32070211,PubMed,10.1080/15476286.2020.1728103,RNA Biol. 2020 Jun;17(6):794-804,cecile.muller@unicaen.fr,"RNases J2, Y and III mutants were affected in virulence in the Galleria mellonella infection model.",M Salze 2020,2020,6 genes,Salze-2020-Study of key RNA metabolism protein,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18579,PHI:11494,UniProt,Q837J2,GenBank,AAO80658,,,V583,cshA (EF0846),,,,,,,1351,Enterococcus faecalis,,V19,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DEAD-box helicase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32070211,PubMed,10.1080/15476286.2020.1728103,RNA Biol. 2020 Jun;17(6):794-804,cecile.muller@unicaen.fr,"RNases J2, Y and III mutants were affected in virulence in the Galleria mellonella infection model.",M Salze 2020,2020,6 genes,Salze-2020-Study of key RNA metabolism protein,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18580,PHI:11495,UniProt,Q836D0,GenBank,AAO80984,,,V583,rnjB (EF1185),,,,,,,1351,Enterococcus faecalis,,V19,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RNase J2,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32070211,PubMed,10.1080/15476286.2020.1728103,RNA Biol. 2020 Jun;17(6):794-804,cecile.muller@unicaen.fr,"RNases J2, Y and III mutants were affected in virulence in the Galleria mellonella infection model.",M Salze 2020,2020,6 genes,Salze-2020-Study of key RNA metabolism protein,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18581,PHI:11496,UniProt,Q82ZG1,GenBank,AAO82778,,,V583,rnc (EF3097),,,,,,,1351,Enterococcus faecalis,,V19,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,RNase III,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32070211,PubMed,10.1080/15476286.2020.1728103,RNA Biol. 2020 Jun;17(6):794-804,cecile.muller@unicaen.fr,"RNases J2, Y and III mutants were affected in virulence in the Galleria mellonella infection model.",M Salze 2020,2020,6 genes,Salze-2020-Study of key RNA metabolism protein,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18582,PHI:11497,UniProt,Q836U7,GenBank,AAO80814,,,V583,cshC (EF1009),,,,,,,1351,Enterococcus faecalis,,V19,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DEAD-box helicase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32070211,PubMed,10.1080/15476286.2020.1728103,RNA Biol. 2020 Jun;17(6):794-804,cecile.muller@unicaen.fr,"RNases J2, Y and III mutants were affected in virulence in the Galleria mellonella infection model.",M Salze 2020,2020,6 genes,Salze-2020-Study of key RNA metabolism protein,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18583,PHI:11498,UniProt,Q835K0,GenBank,AAO81168,,,V583,cshB (EF1377),,,,,,,1351,Enterococcus faecalis,,V19,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DEAD-box helicase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32070211,PubMed,10.1080/15476286.2020.1728103,RNA Biol. 2020 Jun;17(6):794-804,cecile.muller@unicaen.fr,"RNases J2, Y and III mutants were affected in virulence in the Galleria mellonella infection model.",M Salze 2020,2020,6 genes,Salze-2020-Study of key RNA metabolism protein,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18584,PHI:11499,UniProt,Q4I2D7,GenBank,ESU14698,,,PH-1; NRRL 31084,FgcapA (FGSG_08621),chromosome 2,,,FgcapB (FGSG_01226),UniProt: Q4INI2; GenBank: ESU06516,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zimai 22,,,inflorescence,F-actin-capping protein subunit alpha,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31693278,PubMed,10.1111/mpp.12887,Mol Plant Pathol. 2020 Feb;21(2):173-187,chenyun0927@zju.edu.cn,"The deletion mutants ΔFgcapA and ΔFgcapB and the double deletion mutant ΔΔFgcapA/B dramatically reduced hyphal growth, asexual and sexual reproduction and endocytosis.",G Tang 2019,2019,2 genes,Tang-2019-Capping proteins regulate fungal dev,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18585,PHI:11500,UniProt,Q4INI2,GenBank,ESU06516,,,PH-1; NRRL 31084,FgcapB (FGSG_01226),chromosome 1,,,FgcapA (FGSG_08621),UniProt: Q4I2D7; GenBank: ESU14698,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zimai 22,,,inflorescence,F-actin capping protein subunit beta,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31693278,PubMed,10.1111/mpp.12887,Mol Plant Pathol. 2020 Feb;21(2):173-187,chenyun0927@zju.edu.cn,"The deletion mutants ΔFgcapA and ΔFgcapB and the double deletion mutant ΔΔFgcapA/B dramatically reduced hyphal growth, asexual and sexual reproduction and endocytosis.",G Tang 2019,2019,2 genes,Tang-2019-Capping proteins regulate fungal dev,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18586,PHI:11499,UniProt,Q4I2D7,GenBank,ESU14698,,,PH-1; NRRL 31084,FgcapA (FGSG_08621),chromosome 2,,,FgcapB (FGSG_01226),UniProt: Q4INI2; GenBank: ESU06516,PHI:11500,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zimai 22,,,inflorescence,F-actin-capping protein subunit alpha,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31693278,PubMed,10.1111/mpp.12887,Mol Plant Pathol. 2020 Feb;21(2):173-187,chenyun0927@zju.edu.cn,"The deletion mutants ΔFgcapA and ΔFgcapB and the double deletion mutant ΔΔFgcapA/B dramatically reduced hyphal growth, asexual and sexual reproduction and endocytosis.",G Tang 2019,2019,2 genes,Tang-2019-Capping proteins regulate fungal dev,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18587,PHI:11500,UniProt,Q4INI2,GenBank,ESU06516,,,PH-1; NRRL 31084,FgcapB (FGSG_01226),chromosome 1,,,FgcapA (FGSG_08621),UniProt: Q4I2D7; GenBank: ESU14698,PHI:11499,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zimai 22,,,inflorescence,F-actin capping protein subunit beta,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,31693278,PubMed,10.1111/mpp.12887,Mol Plant Pathol. 2020 Feb;21(2):173-187,chenyun0927@zju.edu.cn,"The deletion mutants ΔFgcapA and ΔFgcapB and the double deletion mutant ΔΔFgcapA/B dramatically reduced hyphal growth, asexual and sexual reproduction and endocytosis.",G Tang 2019,2019,2 genes,Tang-2019-Capping proteins regulate fungal dev,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18588,PHI:11501,UniProt,Q9I5W4,GenBank,AE004493_6,,,PAO1,impA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bronchoalveolar lavage fluid; macrophage,immunomodulating metalloprotease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion; gene complementation,,,YVS,31527124,PubMed,10.1128/IAI.00695-19,Infect Immun. 2019 Nov 18;87(12):e00695-19,wuweihui@nankai.edu.cn,ImpA inhibited the phagocytosis of P. aeruginosa by macrophages in vivo.,Z Tian 2019,2019,1 gene,Tian-2019-Pseudomonas aeruginosa ExsA regulate,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18589,PHI:11502,UniProt,Q9I1S4,GenBank,AE004645_13,,,PAO1,ExoY,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,PMVEC,,pulmonary microvascular endothelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32413239,PubMed,10.1096/fj.202000051RRR,FASEB J. 2020 Jul;34(7):9156-9179,tstevens@southalabama.edu,ExoY contributed to the virulence arsenal of P. aeruginosa through the subversion of endothelial amyloid host-defense to promote a lung endothelial-derived cytotoxic proteinopathy.,S Voth 2020,2020,5 genes,Voth-2020-Virulent Pseudomonas aeruginosa infe,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18590,PHI:11502,UniProt,Q9I1S4,GenBank,AE004645_13,,,PAO1,ExoY,,,,,,PHI:11503; PHI:11504,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,PMVEC,,pulmonary microvascular endothelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32413239,PubMed,10.1096/fj.202000051RRR,FASEB J. 2020 Jul;34(7):9156-9179,tstevens@southalabama.edu,ExoY contributed to the virulence arsenal of P. aeruginosa through the subversion of endothelial amyloid host-defense to promote a lung endothelial-derived cytotoxic proteinopathy.,S Voth 2020,2020,5 genes,Voth-2020-Virulent Pseudomonas aeruginosa infe,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18591,PHI:11503,UniProt,G3XDA1,GenBank,AE004801_6,,,PAO1,ExoS,,,,,,PHI:11502; PHI:11504,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,PMVEC,,pulmonary microvascular endothelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32413239,PubMed,10.1096/fj.202000051RRR,FASEB J. 2020 Jul;34(7):9156-9179,tstevens@southalabama.edu,ExoY contributed to the virulence arsenal of P. aeruginosa through the subversion of endothelial amyloid host-defense to promote a lung endothelial-derived cytotoxic proteinopathy.,S Voth 2020,2020,5 genes,Voth-2020-Virulent Pseudomonas aeruginosa infe,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18592,PHI:11504,UniProt,Q9I788,GenBank,AE004444_3,,,PAO1,ExoT,,,,,,PHI:11502; PHI:11503,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,PMVEC,,pulmonary microvascular endothelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32413239,PubMed,10.1096/fj.202000051RRR,FASEB J. 2020 Jul;34(7):9156-9179,tstevens@southalabama.edu,ExoY contributed to the virulence arsenal of P. aeruginosa through the subversion of endothelial amyloid host-defense to promote a lung endothelial-derived cytotoxic proteinopathy.,S Voth 2020,2020,5 genes,Voth-2020-Virulent Pseudomonas aeruginosa infe,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18593,PHI:11505,UniProt,O34208,GenBank,AAC16023,,,PA103,ExoU,,,,,,PHI:11504,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,PMVEC,,pulmonary microvascular endothelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32413239,PubMed,10.1096/fj.202000051RRR,FASEB J. 2020 Jul;34(7):9156-9179,tstevens@southalabama.edu,ExoY contributed to the virulence arsenal of P. aeruginosa through the subversion of endothelial amyloid host-defense to promote a lung endothelial-derived cytotoxic proteinopathy.,S Voth 2020,2020,5 genes,Voth-2020-Virulent Pseudomonas aeruginosa infe,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18594,PHI:11504,UniProt,Q9I788,GenBank,AE004444_3,,,PAO1,ExoT,,,,,,PHI:11505,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,PMVEC,,pulmonary microvascular endothelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32413239,PubMed,10.1096/fj.202000051RRR,FASEB J. 2020 Jul;34(7):9156-9179,tstevens@southalabama.edu,ExoY contributed to the virulence arsenal of P. aeruginosa through the subversion of endothelial amyloid host-defense to promote a lung endothelial-derived cytotoxic proteinopathy.,S Voth 2020,2020,5 genes,Voth-2020-Virulent Pseudomonas aeruginosa infe,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18595,PHI:11502,UniProt,Q9I1S4,GenBank,AE004645_13,,,PAO1,ExoY,,ExoY K81M,,,,,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,PMVEC,,pulmonary microvascular endothelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32413239,PubMed,10.1096/fj.202000051RRR,FASEB J. 2020 Jul;34(7):9156-9179,tstevens@southalabama.edu,ExoY contributed to the virulence arsenal of P. aeruginosa through the subversion of endothelial amyloid host-defense to promote a lung endothelial-derived cytotoxic proteinopathy.,S Voth 2020,2020,5 genes,Voth-2020-Virulent Pseudomonas aeruginosa infe,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18596,PHI:11506,UniProt,G3XD49,GenBank,AE004597_9,,,PAO1,pcrV,,,,,,,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10114,Rattus (related: rat),Sprague-Dawley,PMVEC,,pulmonary microvascular endothelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,32413239,PubMed,10.1096/fj.202000051RRR,FASEB J. 2020 Jul;34(7):9156-9179,tstevens@southalabama.edu,ExoY contributed to the virulence arsenal of P. aeruginosa through the subversion of endothelial amyloid host-defense to promote a lung endothelial-derived cytotoxic proteinopathy.,S Voth 2020,2020,5 genes,Voth-2020-Virulent Pseudomonas aeruginosa infe,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18597,PHI:11507,,no data found,,,,,,zmpA,,,,,,,1502,Clostridium perfringens,,EHE-NE18,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 308,,,,putative zinc metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31924132,PubMed,10.1177/1040638719898689,J Vet Diagn Invest. 2020 Mar;32(2):259-267,rob.moore@rmit.edu.au,"A zmpA–zmpB double mutant also was generated and shown to have significantly reduced virulence, to the same extent as the respective single mutants.",B Wade 2020,2020,2 genes,Wade-2020-Two putative zinc metalloproteases c,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18598,PHI:11508,,no data found,,,,,,zmpB,,,,,,,1502,Clostridium perfringens,,EHE-NE18,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 308,,,,putative zinc metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31924132,PubMed,10.1177/1040638719898689,J Vet Diagn Invest. 2020 Mar;32(2):259-267,rob.moore@rmit.edu.au,"A zmpA–zmpB double mutant also was generated and shown to have significantly reduced virulence, to the same extent as the respective single mutants.",B Wade 2020,2020,2 genes,Wade-2020-Two putative zinc metalloproteases c,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18599,PHI:11507,,no data found,,,,,,zmpA,,,,,,PHI:11508,1502,Clostridium perfringens,,EHE-NE18,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 308,,,,putative zinc metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31924132,PubMed,10.1177/1040638719898689,J Vet Diagn Invest. 2020 Mar;32(2):259-267,rob.moore@rmit.edu.au,"A zmpA–zmpB double mutant also was generated and shown to have significantly reduced virulence, to the same extent as the respective single mutants.",B Wade 2020,2020,2 genes,Wade-2020-Two putative zinc metalloproteases c,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18600,PHI:11508,,no data found,,,,,,zmpB,,,,,,PHI:11507,1502,Clostridium perfringens,,EHE-NE18,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 308,,,,putative zinc metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31924132,PubMed,10.1177/1040638719898689,J Vet Diagn Invest. 2020 Mar;32(2):259-267,rob.moore@rmit.edu.au,"A zmpA–zmpB double mutant also was generated and shown to have significantly reduced virulence, to the same extent as the respective single mutants.",B Wade 2020,2020,2 genes,Wade-2020-Two putative zinc metalloproteases c,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18601,PHI:11507,,no data found,,,,,,zmpA,,,,,,,1502,Clostridium perfringens,,WER-NE36,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 308,,,,putative zinc metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31924132,PubMed,10.1177/1040638719898689,J Vet Diagn Invest. 2020 Mar;32(2):259-267,rob.moore@rmit.edu.au,"A zmpA–zmpB double mutant also was generated and shown to have significantly reduced virulence, to the same extent as the respective single mutants.",B Wade 2020,2020,2 genes,Wade-2020-Two putative zinc metalloproteases c,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18602,PHI:11508,,no data found,,,,,,zmpB,,,,,,,1502,Clostridium perfringens,,56,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 308,,,,putative zinc metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31924132,PubMed,10.1177/1040638719898689,J Vet Diagn Invest. 2020 Mar;32(2):259-267,rob.moore@rmit.edu.au,"A zmpA–zmpB double mutant also was generated and shown to have significantly reduced virulence, to the same extent as the respective single mutants.",B Wade 2020,2020,2 genes,Wade-2020-Two putative zinc metalloproteases c,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18603,PHI:11507,,no data found,,,,,,zmpA,,,,,,,1502,Clostridium perfringens,,56,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),Ross 308,,,,putative zinc metalloprotease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,31924132,PubMed,10.1177/1040638719898689,J Vet Diagn Invest. 2020 Mar;32(2):259-267,rob.moore@rmit.edu.au,"A zmpA–zmpB double mutant also was generated and shown to have significantly reduced virulence, to the same extent as the respective single mutants.",B Wade 2020,2020,2 genes,Wade-2020-Two putative zinc metalloproteases c,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18604,PHI:11509,UniProt,Q7CQY3,GenBank,AAL19637,,,LT2,fur,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,ferric uptake regulation protein,,,,reduced virulence,,,,,,,,wild type,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,31383745,PubMed,10.1128/IAI.00562-19,Infect Immun. 2019 Sep 19;87(10):e00562-19,yus@shvri.ac.cn,The clpV and fur mutant strains were defective in intramacrophage survival compared to S. Typhimurium wild-type.,S Wang 2019,2019,2 genes,Wang-2019-The ferric uptake regulator represse,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18605,PHI:11510,UniProt,H9L4K2,GenBank,CAC48204,,,SR-11,clpV,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,molecular chaperone,,,,reduced virulence,,,,,,,,wild type,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,31383745,PubMed,10.1128/IAI.00562-19,Infect Immun. 2019 Sep 19;87(10):e00562-19,yus@shvri.ac.cn,The clpV and fur mutant strains were defective in intramacrophage survival compared to S. Typhimurium wild-type.,S Wang 2019,2019,2 genes,Wang-2019-The ferric uptake regulator represse,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18606,PHI:11509,UniProt,Q7CQY3,GenBank,AAL19637,,,LT2,fur,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,ferric uptake regulation protein,,,,reduced virulence,,,,,,,,wild type,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,31383745,PubMed,10.1128/IAI.00562-19,Infect Immun. 2019 Sep 19;87(10):e00562-19,yus@shvri.ac.cn,The clpV and fur mutant strains were defective in intramacrophage survival compared to S. Typhimurium wild-type.,S Wang 2019,2019,2 genes,Wang-2019-The ferric uptake regulator represse,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18607,PHI:11510,UniProt,H9L4K2,GenBank,CAC48204,,,SR-11,clpV,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,molecular chaperone,,,,reduced virulence,,,,,,,,wild type,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,31383745,PubMed,10.1128/IAI.00562-19,Infect Immun. 2019 Sep 19;87(10):e00562-19,yus@shvri.ac.cn,The clpV and fur mutant strains were defective in intramacrophage survival compared to S. Typhimurium wild-type.,S Wang 2019,2019,2 genes,Wang-2019-The ferric uptake regulator represse,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18608,PHI:11509,UniProt,Q7CQY3,GenBank,AAL19637,,,LT2,fur,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,ferric uptake regulation protein,,,,reduced virulence,,,,,,,,wild type,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,31383745,PubMed,10.1128/IAI.00562-19,Infect Immun. 2019 Sep 19;87(10):e00562-19,yus@shvri.ac.cn,The clpV and fur mutant strains were defective in intramacrophage survival compared to S. Typhimurium wild-type.,S Wang 2019,2019,2 genes,Wang-2019-The ferric uptake regulator represse,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18609,PHI:11510,UniProt,H9L4K2,GenBank,CAC48204,,,SR-11,clpV,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,molecular chaperone,,,,reduced virulence,,,,,,,,wild type,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,31383745,PubMed,10.1128/IAI.00562-19,Infect Immun. 2019 Sep 19;87(10):e00562-19,yus@shvri.ac.cn,The clpV and fur mutant strains were defective in intramacrophage survival compared to S. Typhimurium wild-type.,S Wang 2019,2019,2 genes,Wang-2019-The ferric uptake regulator represse,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18610,PHI:11509,UniProt,Q7CQY3,GenBank,AAL19637,,,LT2,fur,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,ferric uptake regulation protein,,,,reduced virulence,,,,,,,,wild type,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,31383745,PubMed,10.1128/IAI.00562-19,Infect Immun. 2019 Sep 19;87(10):e00562-19,yus@shvri.ac.cn,The clpV and fur mutant strains were defective in intramacrophage survival compared to S. Typhimurium wild-type.,S Wang 2019,2019,2 genes,Wang-2019-The ferric uptake regulator represse,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18611,PHI:11510,UniProt,H9L4K2,GenBank,CAC48204,,,SR-11,clpV,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SAT52,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,molecular chaperone,,,,reduced virulence,,,,,,,,wild type,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,31383745,PubMed,10.1128/IAI.00562-19,Infect Immun. 2019 Sep 19;87(10):e00562-19,yus@shvri.ac.cn,The clpV and fur mutant strains were defective in intramacrophage survival compared to S. Typhimurium wild-type.,S Wang 2019,2019,2 genes,Wang-2019-The ferric uptake regulator represse,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18612,PHI:11511,UniProt,Q4WAU2,GenBank,EAL84644,,,Af293,Afcps1 (AFUA_7G02500),chromosome 7,,,,,,746128,Aspergillus fumigatus,330879,Af293,aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage; femur; tibia,putative polysaccharide synthase,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; Congo red; caspofungin; calcofluor white,NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,33201436,PubMed,10.1007/s12275-021-0347-x,J Microbiol. 2021 Jan;59(1):64-75,zgwmvp@163.com,Cps1 was necessary for the maintenance of cell wall stability and the adaptation of conidia to the immune response of macrophages in A. fumigatus.,S Wang 2020,2020,2 genes,Wang-2020-The putative polysaccharide synthase,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18613,PHI:11512,UniProt,A4DA44,GenBank,EBA27212,,,Af293,Afcps2 (AFUA_8G02320),chromosome 8,,,,,,746128,Aspergillus fumigatus,330879,Af293,aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage; femur; tibia,capsule polysaccharide synthase,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; Congo red; caspofungin; calcofluor white,NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,33201436,PubMed,10.1007/s12275-021-0347-x,J Microbiol. 2021 Jan;59(1):64-75,zgwmvp@163.com,Cps1 was necessary for the maintenance of cell wall stability and the adaptation of conidia to the immune response of macrophages in A. fumigatus.,S Wang 2020,2020,2 genes,Wang-2020-The putative polysaccharide synthase,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18614,PHI:11513,UniProt,D0NQ89,GenBank,EEY62821,,,T30-4,PiCAT2 (PITG_15248),,,,,,,4787,Phytophthora infestans,,MX5-1,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Impala,,,leaf,catalase,,,,reduced virulence,,yes,,,,reduced,,reduced,,no,H2O2; NaCl; sorbitol,H2O2: CHEBI:16240; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,altered gene expression / gene regulation: silencing,,,YVS,31997544,PubMed,10.1111/mpp.12907,Mol Plant Pathol. 2020 Apr;21(4):460-474,ppguo@cau.edu.cn,"PiCAT2 was required for P. infestans mycelial growth, asexual reproduction, abiotic stress tolerance, and pathogenicity.",T H Wang 2020,2020,1 gene,Wang-2020-A proper PiCAT2 level is critical fo,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18615,PHI:11514,UniProt,J5JFI0,GenBank,EJP62386,,,ARSEF 2860,Bbctf1alpha (BBA_08712),,,,,,,176275,Beauveria bassiana,,CICC 41021,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,zinc finger transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,,no,sodium chloride; hydrogen peroxide; menadione; carbendazim; sodium dodecyl sulfate; Congo red; calcofluor white,sodium chloride: CHEBI:26710; hydrogen peroxide: CHEBI:16240; menadione: CHEBI:28869; carbendazim: CHEBI:3392; sodium dodecyl sulfate: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,32077581,PubMed,10.1002/ps.5797,Pest Manag Sci. 2020 Aug;76(8):2589-2600,yuxiaoping19630306@163.com,"Virulence of each disruption mutant on the greater wax moth was remarkably attenuated in topical immersion. However, there was no significant difference in intrahemolymph injection when the cuticle penetration process was bypassed.",Z L Wang 2020,2020,2 genes,Wang-2020-The zinc finger transcription factor,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18616,PHI:11515,UniProt,J4WFB1,GenBank,EJP68645,,,ARSEF 2860,Bbctf1beta (BBA_02647),,,,,,,176275,Beauveria bassiana,,CICC 41021,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,zinc finger transcription factor,,,,reduced virulence,,,,,,wild type,,wild type,,no,sodium chloride; hydrogen peroxide; menadione; carbendazim; sodium dodecyl sulfate; Congo red; calcofluor white,sodium chloride: CHEBI:26710; hydrogen peroxide: CHEBI:16240; menadione: CHEBI:28869; carbendazim: CHEBI:3392; sodium dodecyl sulfate: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,32077581,PubMed,10.1002/ps.5797,Pest Manag Sci. 2020 Aug;76(8):2589-2600,yuxiaoping19630306@163.com,"Virulence of each disruption mutant on the greater wax moth was remarkably attenuated in topical immersion. However, there was no significant difference in intrahemolymph injection when the cuticle penetration process was bypassed.",Z L Wang 2020,2020,2 genes,Wang-2020-The zinc finger transcription factor,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18617,PHI:11516,,no data found,,,,,,cbs,,,,,,,615,Serratia marcescens,,UMH9,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,spleen; liver,siderophore,,,,unaffected pathogenicity,,,,,,,,,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,32393508,PubMed,10.1128/IAI.00117-20,Infect Immun. 2020 Jul 21;88(8):e00117-20,hmobley@umich.edu,Mutants lacking serratiochelin were significantly outcompeted during cochallenge with wildtype UMH9 in the kidneys and spleen after inoculation via the tail vein in a bacteremia mouse model.,D R Weakland 2020,2020,2 genes,Weakland-2020-The Serratia marcescens sideroph,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18618,PHI:11516,,no data found,,,,,,cbs,,,,,,,615,Serratia marcescens,,UMH9,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney,siderophore,,,,increased virulence (hypervirulence),,,,,,,,,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,32393508,PubMed,10.1128/IAI.00117-20,Infect Immun. 2020 Jul 21;88(8):e00117-20,hmobley@umich.edu,Mutants lacking serratiochelin were significantly outcompeted during cochallenge with wildtype UMH9 in the kidneys and spleen after inoculation via the tail vein in a bacteremia mouse model.,D R Weakland 2020,2020,2 genes,Weakland-2020-The Serratia marcescens sideroph,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18619,PHI:11517,,no data found,,,,,,sch,,,,,,,615,Serratia marcescens,,UMH9,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; spleen; liver,siderophore serratiochelin,,,,reduced virulence,,,,,,,,,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,32393508,PubMed,10.1128/IAI.00117-20,Infect Immun. 2020 Jul 21;88(8):e00117-20,hmobley@umich.edu,Mutants lacking serratiochelin were significantly outcompeted during cochallenge with wildtype UMH9 in the kidneys and spleen after inoculation via the tail vein in a bacteremia mouse model.,D R Weakland 2020,2020,2 genes,Weakland-2020-The Serratia marcescens sideroph,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18620,PHI:11516,,no data found,,,,,,cbs,,,,,,PHI:11517,615,Serratia marcescens,,UMH9,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; spleen; liver,siderophore,,,,reduced virulence,,,,,,,,,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,32393508,PubMed,10.1128/IAI.00117-20,Infect Immun. 2020 Jul 21;88(8):e00117-20,hmobley@umich.edu,Mutants lacking serratiochelin were significantly outcompeted during cochallenge with wildtype UMH9 in the kidneys and spleen after inoculation via the tail vein in a bacteremia mouse model.,D R Weakland 2020,2020,2 genes,Weakland-2020-The Serratia marcescens sideroph,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18621,PHI:11517,,no data found,,,,,,sch,,,,,,PHI:11516,615,Serratia marcescens,,UMH9,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,kidney; spleen; liver,siderophore serratiochelin,,,,reduced virulence,,,,,,,,,,no,"2,2'-dipyridyl","2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,32393508,PubMed,10.1128/IAI.00117-20,Infect Immun. 2020 Jul 21;88(8):e00117-20,hmobley@umich.edu,Mutants lacking serratiochelin were significantly outcompeted during cochallenge with wildtype UMH9 in the kidneys and spleen after inoculation via the tail vein in a bacteremia mouse model.,D R Weakland 2020,2020,2 genes,Weakland-2020-The Serratia marcescens sideroph,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18622,PHI:11518,UniProt,P9WKX5,GenBank,CCP46503,,,H37Rv,rv3679,,,,rv3680,UniProt: I6Y498; GenBank: CCP46504,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,putative ATPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,32482725,PubMed,10.1128/JB.00202-20,J Bacteriol. 2020 Jun 1:JB.00202-20,sae2004@med.cornell.edu,Δrv3679-80 mutant suffered from a glycerol-dependent recovery defect on agar plates following mouse infection.,M Whitaker 2020,2020,2 genes,Whitaker-2020-Two interacting ATPases protect,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18623,PHI:11519,UniProt,I6Y498,GenBank,CCP46504,,,H37Rv,rv3680,,,,rv3679,UniProt: P9WKX5; GenBank: CCP46503,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,probable anion transporter ATPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,32482725,PubMed,10.1128/JB.00202-20,J Bacteriol. 2020 Jun 1:JB.00202-20,sae2004@med.cornell.edu,Δrv3679-80 mutant suffered from a glycerol-dependent recovery defect on agar plates following mouse infection.,M Whitaker 2020,2020,2 genes,Whitaker-2020-Two interacting ATPases protect,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18624,PHI:11518,UniProt,P9WKX5,GenBank,CCP46503,,,H37Rv,rv3679,,,,rv3680,UniProt: I6Y498; GenBank: CCP46504,PHI:11519,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,putative ATPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,32482725,PubMed,10.1128/JB.00202-20,J Bacteriol. 2020 Jun 1:JB.00202-20,sae2004@med.cornell.edu,Δrv3679-80 mutant suffered from a glycerol-dependent recovery defect on agar plates following mouse infection.,M Whitaker 2020,2020,2 genes,Whitaker-2020-Two interacting ATPases protect,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18625,PHI:11519,UniProt,I6Y498,GenBank,CCP46504,,,H37Rv,rv3680,,,,rv3679,UniProt: P9WKX5; GenBank: CCP46503,PHI:11518,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,probable anion transporter ATPase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,32482725,PubMed,10.1128/JB.00202-20,J Bacteriol. 2020 Jun 1:JB.00202-20,sae2004@med.cornell.edu,Δrv3679-80 mutant suffered from a glycerol-dependent recovery defect on agar plates following mouse infection.,M Whitaker 2020,2020,2 genes,Whitaker-2020-Two interacting ATPases protect,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18626,PHI:11520,UniProt,A0A7G1LEG5,GenBank,AXV32096,,,ZYAH72,cpxA (BFW97_22315),,,,,,PHI:11521,644,Aeromonas hydrophila,,ZYAH72,diarrhea; nausea; vomiting,bony fishes,7955,Danio rerio (related: zebrafish),,,,,envelope stress sensor histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30184189,PubMed,10.1093/femsle/fny218,FEMS Microbiol Lett. 2018 Nov 1;365(22),zhouyang8728@gmail.com,"Compared to the wild type strain, the knockout mutant strain ΔcpxA/R exhibited a significant impairment in adherence to human epithelial cells Caco-2 and resistance against host killing in fish blood.",Q Xie 2018,2018,2 genes,Xie-2018-The two-component regulatory system C,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18627,PHI:11521,UniProt,A0A347ABL3,GenBank,AXV32095,,,ZYAH72,cpxR (BFW97_22310),,,,,,PHI:11520,644,Aeromonas hydrophila,,ZYAH72,diarrhea; nausea; vomiting,bony fishes,7959,Ctenopharyngodon idella (related: grass carp),,,,,DNA-binding response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30184189,PubMed,10.1093/femsle/fny218,FEMS Microbiol Lett. 2018 Nov 1;365(22),zhouyang8728@gmail.com,"Compared to the wild type strain, the knockout mutant strain ΔcpxA/R exhibited a significant impairment in adherence to human epithelial cells Caco-2 and resistance against host killing in fish blood.",Q Xie 2018,2018,2 genes,Xie-2018-The two-component regulatory system C,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18628,PHI:11522,UniProt,E9EL64,GenBank,EFZ03131,,,ARSEF 23,DNM1 (MAA_00205),,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemocoel,dynamin 2,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32631867,PubMed,10.1128/AEM.01217-20,Appl Environ Microbiol. 2020 Aug 18;86(17):e01217-20,bhuang@ahau.edu.cn,Disruption of Dnm1 impaired the virulence (both topical inoculation and injection) of M. robertsii in the insect Galleria mellonella.,X Xie 2020,2020,1 gene,"Xie-2020-DNM1, a Dynamin-Related Protein That",BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18629,PHI:11523,UniProt,A0A384J8A7,GenBank,ATZ46564,,,B05.10,BcTOR (BCIN_01g11360),BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,gray mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Micro-Tom,,,leaf; fruit,target of rapamycin,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,rapamycin,rapamycin: CHEBI:91681,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,31622007,PubMed,10.1111/mpp.12873,Mol Plant Pathol. 2019 Dec;20(12):1722-1739,renmaozhi@cqu.edu.cn,Pathogenicity assay showed that BcTOR inhibition efficiently reduces the infection of B. cinerea in plant leaves of Arabidopsis and potato or tomato fruits.,F Xiong 2019,2019,1 gene,Xiong-2019-Host-induced gene silencing of BcTO,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18630,PHI:11523,UniProt,A0A384J8A7,GenBank,ATZ46564,,,B05.10,BcTOR (BCIN_01g11360),BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,gray mold,eudicots,4113,Solanum tuberosum (related: potato),cv. Desirée,,,leaf,target of rapamycin,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,rapamycin,rapamycin: CHEBI:91681,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,31622007,PubMed,10.1111/mpp.12873,Mol Plant Pathol. 2019 Dec;20(12):1722-1739,renmaozhi@cqu.edu.cn,Pathogenicity assay showed that BcTOR inhibition efficiently reduces the infection of B. cinerea in plant leaves of Arabidopsis and potato or tomato fruits.,F Xiong 2019,2019,1 gene,Xiong-2019-Host-induced gene silencing of BcTO,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18631,PHI:11524,UniProt,A0A194WD53,GenBank,KUI74329,,,03-8,VM1G_09934 (VmSNF1),chromosome 12,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,nonspecific serine/threonine protein kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32222083,PubMed,10.1111/nph.16561,New Phytol. 2020 Aug;227(3):899-913,huanglili@nwsuaf.edu.cn,"Overexpression of Vm-milR16, but not mutated Vm-milR16, signi?cantly reduced the expression of targets and virulence of V.mali.",M Xu 2020,2020,3 genes,Xu-2020-Adaptive regulation of virulence genes,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18632,PHI:11525,UniProt,A0A194VIY4,GenBank,KUI63952,,,03-8,VM1G_10693 (VmDODA),,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,"4,5-DOPA dioxygenase extradiol",,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32222083,PubMed,10.1111/nph.16561,New Phytol. 2020 Aug;227(3):899-913,huanglili@nwsuaf.edu.cn,"Overexpression of Vm-milR16, but not mutated Vm-milR16, signi?cantly reduced the expression of targets and virulence of V.mali.",M Xu 2020,2020,3 genes,Xu-2020-Adaptive regulation of virulence genes,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18633,PHI:11526,UniProt,A0A194WAG6,GenBank,KUI73317,,,03-8,VM1G_11912 (VmHy1),chromosome 10,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,hypothetical protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32222083,PubMed,10.1111/nph.16561,New Phytol. 2020 Aug;227(3):899-913,huanglili@nwsuaf.edu.cn,"Overexpression of Vm-milR16, but not mutated Vm-milR16, signi?cantly reduced the expression of targets and virulence of V.mali.",M Xu 2020,2020,3 genes,Xu-2020-Adaptive regulation of virulence genes,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18634,PHI:11527,,no data found,,,,,,gnaA (BGV75_06155),,,,,,,470,Acinetobacter baumannii,497978,MDR-ZJ06,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,UDP-N-acetylglucosamine C-6 dehydrogenase,,,,reduced virulence,,,,,,,,,,no,tigecycline; carbapenem; cephalosporin; colistin; minocycline,tigecycline: CHEBI:149836; carbapenem: CHEBI:46633; cephalosporin: CHEBI:23066; colistin: CHEBI:37943; minocycline: CHEBI:50694,,,,,gene deletion: full; gene complementation,,,YVS,31358579,PubMed,10.1128/AAC.00694-19,Antimicrob Agents Chemother. 2019 Sep 23;63(10):e00694-19,xiaotinghua@zju.edu.cn,GnaA was important for the synthesis of lipooligosaccharide and capsular polysaccharide and that disruption of the gene reduced the virulence of the pathogen.,Q Xu 2019,2019,1 gene,Xu-2019-Dual role of gnaA in antibiotic resist,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18635,PHI:11528,UniProt,A0A0L0V0Y3,,,,,,Pst_13661,,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. CB037,,,leaf,polysaccharide deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,31981296,PubMed,10.1111/pbi.13345,Plant Biotechnol J. 2020 Aug;18(8):1830-1842,kangzs@nwsuaf.edu.cn,"The transgenic wheat expressing the RNA interference (RNAi) construct of Pst_13661 exhibited high resistance to major Pst epidemic races CYR31, CYR32 and CYR33 by inhibiting growth and development of Pst.",Q Xu 2020,2020,1 gene,Xu-2020-A polysaccharide deacetylase from Pucc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18636,PHI:11529,UniProt,G4N7S6,GenBank,EHA50880,,,70-15,MoHAT1 (MGG_06375),chromosome 4,,,MoAtg3 (MGG_02959); MoAtg9 (MGG_09559),UniProt: Q51LD2; GenBank: EHA46004; UniProt: Q51WZ9; GenBank: EHA52375,,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,histone acetyltransferase type B catalytic subunit,,,,reduced virulence,,yes,yes,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30776962,PubMed,10.1080/15548627.2019.1580104,Autophagy. 2019 Jul;15(7):1234-1257,zhgzhang@njau.edu.cn,Acetylation of MoAtg3 and MoAtg9 by MoHat1 was linked to functional appressorium development and pathogenicity.,Z Yin 2019,2019,3 genes,Yin-2019-Histone acetyltransferase MoHat1 acet,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18637,PHI:11530,UniProt,Q51LD2,GenBank,EHA46004,,,70-15,MoAtg3 (MGG_02959),chromosome 7,"ΔMoatg3/MoATG3 K262,267R",,MoHAT1 (MGG_06375),UniProt: G4N7S6; GenBank: EHA50880,,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,autophagy-related protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30776962,PubMed,10.1080/15548627.2019.1580104,Autophagy. 2019 Jul;15(7):1234-1257,zhgzhang@njau.edu.cn,Acetylation of MoAtg3 and MoAtg9 by MoHat1 was linked to functional appressorium development and pathogenicity.,Z Yin 2019,2019,3 genes,Yin-2019-Histone acetyltransferase MoHat1 acet,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18638,PHI:11531,UniProt,Q51WZ9,GenBank,EHA52375,,,70-15,MoAtg9 (MGG_09559),chromosome 3,ΔMoatg9/MoATG9 K621R,,MoHAT1 (MGG_06375),UniProt: G4N7S6; GenBank: EHA50880,,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,autophagy-related protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,30776962,PubMed,10.1080/15548627.2019.1580104,Autophagy. 2019 Jul;15(7):1234-1257,zhgzhang@njau.edu.cn,Acetylation of MoAtg3 and MoAtg9 by MoHat1 was linked to functional appressorium development and pathogenicity.,Z Yin 2019,2019,3 genes,Yin-2019-Histone acetyltransferase MoHat1 acet,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18639,PHI:11532,UniProt,G4NDR3,GenBank,EHA48501,,,70-15,MoMck1 (MGG_00883),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitogen-activated protein kinase kinase kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18640,PHI:11532,UniProt,G4NDR3,GenBank,EHA48501,,,70-15,MoMck1 (MGG_00883),chromosome 5,,,,,PHI:11533,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitogen-activated protein kinase kinase kinase,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18641,PHI:11533,UniProt,Q52EB3,GenBank,EHA50859,,,70-15,MoAtg1 (MGG_06393),chromosome 4,,,,,PHI:11532,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,serine/threonine-protein kinase,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18642,PHI:11532,UniProt,G4NDR3,GenBank,EHA48501,,,70-15,MoMck1 (MGG_00883),chromosome 5,,,,,PHI:11534,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitogen-activated protein kinase kinase kinase,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18643,PHI:11534,UniProt,Q51UJ9,GenBank,EHA58358,,,70-15,MoAtg11 (MGG_04486),chromosome 1,,,,,PHI:11532,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,autophagy-related protein,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18644,PHI:11532,UniProt,G4NDR3,GenBank,EHA48501,,,70-15,MoMck1 (MGG_00883),chromosome 5,,,,,PHI:11535,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitogen-activated protein kinase kinase kinase,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18645,PHI:11535,UniProt,Q51Y68,GenBank,EHA51796,,,70-15,MoAtg17 (MGG_07667),chromosome 3,,,,,PHI:11532,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,autophagy-related protein,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18646,PHI:11532,UniProt,G4NDR3,GenBank,EHA48501,,,70-15,MoMck1 (MGG_00883),chromosome 5,,,,,PHI:11536,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitogen-activated protein kinase kinase kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18647,PHI:11536,UniProt,G4NC26,GenBank,EHA49029,,,70-15,MoAtg13 (MGG_00454),chromosome 5,,,,,PHI:11532,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18648,PHI:11537,UniProt,G4N6Z6,GenBank,EHA50761,,,70-15,MoMkk1 (MGG_06482),chromosome 4,,,MoAtg1 (MGG_06393); MoAtg11 (MGG_04486); MoAtg17 (MGG_07667); MoAtg13 (MGG_00454),UniProt: Q52EB3; GenBank: EHA50859; UniProt: Q51UJ9; GenBank: EHA58358; UniProt: Q51Y68; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitogen-activated protein kinase kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18649,PHI:11537,UniProt,G4N6Z6,GenBank,EHA50761,,,70-15,MoMkk1 (MGG_06482),chromosome 4,,,MoAtg1 (MGG_06393); MoAtg11 (MGG_04486); MoAtg17 (MGG_07667); MoAtg13 (MGG_00454),UniProt: Q52EB3; GenBank: EHA50859; UniProt: Q51UJ9; GenBank: EHA58358; UniProt: Q51Y68; Gen,PHI:11533,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitogen-activated protein kinase kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18650,PHI:11533,UniProt,Q52EB3,GenBank,EHA50859,,,70-15,MoAtg1 (MGG_06393),chromosome 4,,,MoMkk1 (MGG_06482),UniProt: G4N6Z6; GenBank: EHA50761,PHI:11537,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,serine/threonine-protein kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18651,PHI:11537,UniProt,G4N6Z6,GenBank,EHA50761,,,70-15,MoMkk1 (MGG_06482),chromosome 4,,,MoAtg1 (MGG_06393); MoAtg11 (MGG_04486); MoAtg17 (MGG_07667); MoAtg13 (MGG_00454),UniProt: Q52EB3; GenBank: EHA50859; UniProt: Q51UJ9; GenBank: EHA58358; UniProt: Q51Y68; Gen,PHI:11534,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitogen-activated protein kinase kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18652,PHI:11534,UniProt,Q51UJ9,GenBank,EHA58358,,,70-15,MoAtg11 (MGG_04486),chromosome 1,,,MoMkk1 (MGG_06482),UniProt: G4N6Z6; GenBank: EHA50761,PHI:11537,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18653,PHI:11537,UniProt,G4N6Z6,GenBank,EHA50761,,,70-15,MoMkk1 (MGG_06482),chromosome 4,,,MoAtg1 (MGG_06393); MoAtg11 (MGG_04486); MoAtg17 (MGG_07667); MoAtg13 (MGG_00454),UniProt: Q52EB3; GenBank: EHA50859; UniProt: Q51UJ9; GenBank: EHA58358; UniProt: Q51Y68; Gen,PHI:11535,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitogen-activated protein kinase kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18654,PHI:11535,UniProt,Q51Y68,GenBank,EHA51796,,,70-15,MoAtg17 (MGG_07667),chromosome 3,,,MoMkk1 (MGG_06482),UniProt: G4N6Z6; GenBank: EHA50761,PHI:11537,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18655,PHI:11537,UniProt,G4N6Z6,GenBank,EHA50761,,,70-15,MoMkk1 (MGG_06482),chromosome 4,,,MoAtg1 (MGG_06393); MoAtg11 (MGG_04486); MoAtg17 (MGG_07667); MoAtg13 (MGG_00454),UniProt: Q52EB3; GenBank: EHA50859; UniProt: Q51UJ9; GenBank: EHA58358; UniProt: Q51Y68; Gen,PHI:11536,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,mitogen-activated protein kinase kinase,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18656,PHI:11536,UniProt,G4NC26,GenBank,EHA49029,,,70-15,MoAtg13 (MGG_00454),chromosome 5,,,MoMkk1 (MGG_06482),UniProt: G4N6Z6; GenBank: EHA50761,PHI:11537,318829,Magnaporthe oryzae,,Guy11,blast (rice),eudicots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,dithiothreitol (DTT),dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,31313634,PubMed,10.1080/15548627.2019.1644075,Autophagy. 2020 May;16(5):900-916,zhgzhang@njau.edu.cn,MoAtg1-dependent MoMkk1 phosphorylation was essential for the pathogenicity of M. oryzae.,Z Yin 2019,2019,6 genes,Yin-2019-Shedding light on autophagy coordinat,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18657,PHI:11538,UniProt,C0RII4,GenBank,ACO00642,,,ATCC 23457,tatA (A0889),chromosome I,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,lipid A biosynthesis acyltransferase,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18658,PHI:11538,UniProt,C0RII4,GenBank,ACO00642,,,ATCC 23457,tatA (A0889),chromosome I,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,lipid A biosynthesis acyltransferase,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18659,PHI:11539,UniProt,C0RG76,GenBank,ACN99833,,,ATCC 23457,A0009,chromosome I,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,extracellular solute-binding protein family 5,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18660,PHI:11540,UniProt,C0RH54,GenBank,ACO00162,,,ATCC 23457,A0376,chromosome I,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,invasion associated locus B family protein,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18661,PHI:11541,UniProt,C0RKL0,GenBank,ACO02143,,,ATCC 23457,B0279,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,ABC transporter substrate-binding protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18662,PHI:11542,UniProt,C0RL06,GenBank,ACO02289,,,ATCC 23457,B0446,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,ABC transporter substrate-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18663,PHI:11543,UniProt,C0RL72,GenBank,ACO02355,,,ATCC 23457,B0520,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,periplasmic substrate-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18664,PHI:11544,UniProt,C0RLS8,GenBank,ACO02561,,,ATCC 23457,B0754,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,ABC transporter substrate-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18665,PHI:11545,UniProt,C0RLV2,GenBank,ACO02585,,,ATCC 23457,B0779,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,ABC transporter substrate-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18666,PHI:11546,UniProt,C0RM94,GenBank,ACO02727,,,ATCC 23457,B0934,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,MetQ/NlpA family ABC transporter substrate-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18667,PHI:11547,UniProt,C0RH74,GenBank,ACO00182,,,ATCC 23457,A0396,chromosome I,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,disulfide bond reductase DsbA family protein,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18668,PHI:11548,UniProt,C0RJX0,GenBank,ACO01903,,,ATCC 23457,B0019,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18669,PHI:11549,UniProt,C0RKI3,GenBank,ACO02116,,,ATCC 23457,B0251,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,"nitrite reductase, copper-containing",,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18670,PHI:11550,UniProt,C0RLK7,GenBank,ACO02490,,,ATCC 23457,B0672,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,multicopper oxidase,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18671,PHI:11551,UniProt,C0RMC2,GenBank,ACO02755,,,ATCC 23457,B0965,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,methionine sulfoxide reductase catalytic subunit,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18672,PHI:11552,UniProt,C0RHP4,GenBank,ACO00352,,,ATCC 23457,A0577,chromosome I,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,"L,D-transpeptidase",,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18673,PHI:11553,UniProt,C0RI72,GenBank,ACO00530,,,ATCC 23457,A0773,chromosome I,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,"murein L,D-transpeptidase",,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18674,PHI:11554,UniProt,C0RE70,GenBank,ACO01192,,,ATCC 23457,A1479,chromosome I,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,cell envelope-related amide hydrolase,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18675,PHI:11555,UniProt,C0RH22,GenBank,ACO00130,,,ATCC 23457,A0340,chromosome I,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,CAP domain-containing protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18676,PHI:11556,,no data found,GenBank,ADZ88457,,,M5-90,B0340,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,P1 family peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18677,PHI:11557,UniProt,C0RLR2,GenBank,ACO02545,,,ATCC 23457,B0737,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,hint domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18678,PHI:11558,,no data found,,,,,,RS03245,,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,TIGR02301 family protein,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18679,PHI:11559,UniProt,C0RKI1,GenBank,ACO02114,,,ATCC 23457,B0249,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,lipase,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18680,PHI:11560,UniProt,C0RLE7,GenBank,ACO02430,,,ATCC 23457,B0604,chromosome II,,,,,,29459,Brucella melitensis,941967,M28,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; bone marrow-derived macrophage,amidohydrolase,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); EDTA; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; EDTA: CHEBI:64758; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,32778612,PubMed,10.1128/IAI.00389-20,Infect Immun. 2020 Oct 19;88(11):e00389-20,buzhigao@caas.cn,Loss of Tat significantly attenuated B. melitensis infection in murine macrophages ex vivo and was required for full virulence of B. melitensis M28 in mouse model for persistent infection.,X Yan 2020,2020,23 genes,Yan-2020-The twin arginine translocation syste,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18681,PHI:11561,,no data found,,,,,,Fg12,,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,eudicots,3847,Glycine max (related: soybean),cv. Hefeng 47,,,hypocotyl,ribonuclease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32725938,PubMed,10.1111/jipb.12997,J Integr Plant Biol. 2021 Feb;63(2):365-377,wangyc@njau.edu.cn,Transient expression of Fg12 in Nicotiana benthamiana induced cell death in a light-dependent manner.,B Yang 2020,2020,1 gene,Yang-2020-Fg12 ribonuclease secretion contribu,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18682,PHI:11561,,no data found,,,,,,Fg12,,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,ribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,32725938,PubMed,10.1111/jipb.12997,J Integr Plant Biol. 2021 Feb;63(2):365-377,wangyc@njau.edu.cn,Transient expression of Fg12 in Nicotiana benthamiana induced cell death in a light-dependent manner.,B Yang 2020,2020,1 gene,Yang-2020-Fg12 ribonuclease secretion contribu,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18683,PHI:11561,,no data found,,,,,,Fg12,,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,ribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,32725938,PubMed,10.1111/jipb.12997,J Integr Plant Biol. 2021 Feb;63(2):365-377,wangyc@njau.edu.cn,Transient expression of Fg12 in Nicotiana benthamiana induced cell death in a light-dependent manner.,B Yang 2020,2020,1 gene,Yang-2020-Fg12 ribonuclease secretion contribu,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18684,PHI:11561,,no data found,,,,,,Fg12,,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,ribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,32725938,PubMed,10.1111/jipb.12997,J Integr Plant Biol. 2021 Feb;63(2):365-377,wangyc@njau.edu.cn,Transient expression of Fg12 in Nicotiana benthamiana induced cell death in a light-dependent manner.,B Yang 2020,2020,1 gene,Yang-2020-Fg12 ribonuclease secretion contribu,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18685,PHI:11562,UniProt,G2WRK7,GenBank,EGY13508,,,VdLs.17,VdPKS1 (VDAG_00190),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,conidial yellow pigment biosynthesis polyketide synthase,,,,reduced virulence,,,,,,reduced,,aberrant,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,28755294,PubMed,10.1007/s11427-017-9075-3,Sci China Life Sci. 2017 Aug;60(8):868-879,jiafeng_huang@163.com,"The VdPKS1 gene-disruption mutant (vdpks1) formed melanin-deficient albino microsclerotia, which did not affect the fungal colonization in host tissues but significantly reduced the disease severity.",T Zhang 2017,2017,1 gene,Zhang-2017-VdPKS1 is required for melanin form,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18686,PHI:11563,UniProt,A0A0L7TY46,GenBank,NMU85962,,,Vb0551,barA,,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phosphorelay protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32281204,PubMed,10.1096/fj.201902630R,FASEB J. 2020 Jun;34(6):7561-7577,Junzheng@um.edu.mo,"BarA/UvrY not only controlled the virulence factors in V. parahaemolyticus including Type III and Type VI secretion systems, but also attenuated innate immune responses in C. elegans and zebrafish models.",W Zhang 2020,2020,2 genes,Zhang-2020-Organism dual RNA-seq reveals the i,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18687,PHI:11564,UniProt,A0A072LCF3,GenBank,AWG78323,,,R14,uvrY,chromosome 1,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,DNA-binding response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32281204,PubMed,10.1096/fj.201902630R,FASEB J. 2020 Jun;34(6):7561-7577,Junzheng@um.edu.mo,"BarA/UvrY not only controlled the virulence factors in V. parahaemolyticus including Type III and Type VI secretion systems, but also attenuated innate immune responses in C. elegans and zebrafish models.",W Zhang 2020,2020,2 genes,Zhang-2020-Organism dual RNA-seq reveals the i,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18688,PHI:11563,UniProt,A0A0L7TY46,GenBank,NMU85962,,,Vb0551,barA,,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,phosphorelay protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32281204,PubMed,10.1096/fj.201902630R,FASEB J. 2020 Jun;34(6):7561-7577,Junzheng@um.edu.mo,"BarA/UvrY not only controlled the virulence factors in V. parahaemolyticus including Type III and Type VI secretion systems, but also attenuated innate immune responses in C. elegans and zebrafish models.",W Zhang 2020,2020,2 genes,Zhang-2020-Organism dual RNA-seq reveals the i,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18689,PHI:11564,UniProt,A0A072LCF3,GenBank,AWG78323,,,R14,uvrY,chromosome 1,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,DNA-binding response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32281204,PubMed,10.1096/fj.201902630R,FASEB J. 2020 Jun;34(6):7561-7577,Junzheng@um.edu.mo,"BarA/UvrY not only controlled the virulence factors in V. parahaemolyticus including Type III and Type VI secretion systems, but also attenuated innate immune responses in C. elegans and zebrafish models.",W Zhang 2020,2020,2 genes,Zhang-2020-Organism dual RNA-seq reveals the i,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18690,PHI:11564,UniProt,A0A072LCF3,GenBank,AWG78323,,,R14,uvrY,chromosome 1,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,DNA-binding response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32281204,PubMed,10.1096/fj.201902630R,FASEB J. 2020 Jun;34(6):7561-7577,Junzheng@um.edu.mo,Deletion of uvrY compromised bacterial virulence toward HeLa cells.,W Zhang 2020,2020,2 genes,Zhang-2020-Organism dual RNA-seq reveals the i,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18691,PHI:11565,,no data found,,,,,,prhp,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,phenolic acid decarboxylase regulator (PadR) like regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31392803,PubMed,10.1111/mpp.12854,Mol Plant Pathol. 2019 Nov;20(11):1477-1490,bioyongzhang@swu.edu.cn,PrhP greatly promoted the infection process of R. solanacearum as well as the degradation of ferulic acid and salicylic acid.,Y Zhang 2019,2019,4 genes,Zhang-2019-Involvement of a PadR regulator Prh,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18692,PHI:11566,UniProt,D8NG29,GenBank,CBJ39853,,,CMR15,fcs,,,,,,PHI:11567; PHI:11568,305,Ralstonia solanacearum,1429399,OE1-1,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,"coenzyme A ligase, putative long-chain-fatty-acid--CoA ligase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31392803,PubMed,10.1111/mpp.12854,Mol Plant Pathol. 2019 Nov;20(11):1477-1490,bioyongzhang@swu.edu.cn,PrhP greatly promoted the infection process of R. solanacearum as well as the degradation of ferulic acid and salicylic acid.,Y Zhang 2019,2019,4 genes,Zhang-2019-Involvement of a PadR regulator Prh,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18693,PHI:11567,UniProt,Q8Y0F3,GenBank,CAD14793,,,GMI1000,nagAa,,,,,,PHI:11566; PHI:11568,305,Ralstonia solanacearum,1429399,OE1-1,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,probable ferredoxin oxidoreductase oxidoreductase protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31392803,PubMed,10.1111/mpp.12854,Mol Plant Pathol. 2019 Nov;20(11):1477-1490,bioyongzhang@swu.edu.cn,PrhP greatly promoted the infection process of R. solanacearum as well as the degradation of ferulic acid and salicylic acid.,Y Zhang 2019,2019,4 genes,Zhang-2019-Involvement of a PadR regulator Prh,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18694,PHI:11568,UniProt,Q8Y0F9,GenBank,CAD14787,,,GMI1000,nagL,,,,,,PHI:11566; PHI:11567,305,Ralstonia solanacearum,1429399,OE1-1,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,probable glutathione s-transferase protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31392803,PubMed,10.1111/mpp.12854,Mol Plant Pathol. 2019 Nov;20(11):1477-1490,bioyongzhang@swu.edu.cn,PrhP greatly promoted the infection process of R. solanacearum as well as the degradation of ferulic acid and salicylic acid.,Y Zhang 2019,2019,4 genes,Zhang-2019-Involvement of a PadR regulator Prh,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18695,PHI:11565,,no data found,,,,,,prhp,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,phenolic acid decarboxylase regulator (PadR) like regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,31392803,PubMed,10.1111/mpp.12854,Mol Plant Pathol. 2019 Nov;20(11):1477-1490,bioyongzhang@swu.edu.cn,PrhP greatly promoted the infection process of R. solanacearum as well as the degradation of ferulic acid and salicylic acid.,Y Zhang 2019,2019,4 genes,Zhang-2019-Involvement of a PadR regulator Prh,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18696,PHI:11566,UniProt,D8NG29,GenBank,CBJ39853,,,CMR15,fcs,,,,,,PHI:11567; PHI:11568,305,Ralstonia solanacearum,1429399,OE1-1,wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,"coenzyme A ligase, putative long-chain-fatty-acid--CoA ligase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31392803,PubMed,10.1111/mpp.12854,Mol Plant Pathol. 2019 Nov;20(11):1477-1490,bioyongzhang@swu.edu.cn,PrhP greatly promoted the infection process of R. solanacearum as well as the degradation of ferulic acid and salicylic acid.,Y Zhang 2019,2019,4 genes,Zhang-2019-Involvement of a PadR regulator Prh,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18697,PHI:11567,UniProt,Q8Y0F3,GenBank,CAD14793,,,GMI1000,nagAa,,,,,,PHI:11566; PHI:11568,305,Ralstonia solanacearum,1429399,OE1-1,wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,probable ferredoxin oxidoreductase oxidoreductase protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31392803,PubMed,10.1111/mpp.12854,Mol Plant Pathol. 2019 Nov;20(11):1477-1490,bioyongzhang@swu.edu.cn,PrhP greatly promoted the infection process of R. solanacearum as well as the degradation of ferulic acid and salicylic acid.,Y Zhang 2019,2019,4 genes,Zhang-2019-Involvement of a PadR regulator Prh,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18698,PHI:11568,UniProt,Q8Y0F9,GenBank,CAD14787,,,GMI1000,nagL,,,,,,PHI:11566; PHI:11567,305,Ralstonia solanacearum,1429399,OE1-1,wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,leaf,probable glutathione s-transferase protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,31392803,PubMed,10.1111/mpp.12854,Mol Plant Pathol. 2019 Nov;20(11):1477-1490,bioyongzhang@swu.edu.cn,PrhP greatly promoted the infection process of R. solanacearum as well as the degradation of ferulic acid and salicylic acid.,Y Zhang 2019,2019,4 genes,Zhang-2019-Involvement of a PadR regulator Prh,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18699,PHI:11569,UniProt,Q5AHA0,GenBank,AAC39451,,,SC5314,chk1,,,,,,,5476,Candida albicans,237561,SC5314,oropharyngeal candidiasis,primates,9606,Homo sapiens (related: human),HOK cell line,,,oral mucosa,histidine protein kinase 1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33635358,PubMed,10.1007/s00253-021-11187-0,Appl Microbiol Biotechnol. 2021 Mar;105(6):2485-2496,zhouxd@scu.edu.cn,The chk1Δ/Δ mutant failed to adhere and invade oral epithelial cells.,Y Zhou 2021,2021,1 gene,Zhou-2021-Candida albicans CHK1 gene from two-,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18700,PHI:11569,UniProt,Q5AHA0,GenBank,AAC39451,,,SC5314,chk1,,,,,,,5476,Candida albicans,237561,SC5314,oropharyngeal candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,tongue; oral mucosa,histidine protein kinase 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,33635358,PubMed,10.1007/s00253-021-11187-0,Appl Microbiol Biotechnol. 2021 Mar;105(6):2485-2496,zhouxd@scu.edu.cn,The chk1Δ/Δ also failed to cause oral candidiasis in both immunocompetent and immunodeficient mice.,Y Zhou 2021,2021,1 gene,Zhou-2021-Candida albicans CHK1 gene from two-,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18701,PHI:11570,UniProt,R4ZAR0,GenBank,AIK76292,,,GBS6,metP,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood; blood plasma,methionine permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,Methionine and manganese transporters were crucial for GBS growth in human whole blood and plasma.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18702,PHI:11571,UniProt,Q7WYI8,GenBank,AIK76191,,,GBS6,mtsA,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood; blood plasma,substrate-binding lipoprotein of manganese transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,Methionine and manganese transporters were crucial for GBS growth in human whole blood and plasma.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18703,PHI:11572,,no data found,GenBank,AIX05486,,,CNCTC 10/84,W903_1820,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood,small multidrug export family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,A putative small multidrug export family protein contributed significantly to GBS growth in whole blood.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18704,PHI:11572,,no data found,GenBank,AIX05486,,,CNCTC 10/84,W903_1820,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood plasma,small multidrug export family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,A putative small multidrug export family protein contributed significantly to GBS growth in whole blood.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18705,PHI:11573,UniProt,Q8E0U0,GenBank,AE014219_18,,,2603V/R,aroA,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood; blood plasma,3-phosphoshikimate 1-carboxyvinyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,AroA of the shikimate pathway was required for GBS growth in both whole blood and plasma.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18706,PHI:11574,UniProt,A0A0G2Z8C7,GenBank,AKI95824,,,SS1,srr1,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood,serine-rich repeat 1 glycoprotein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,Deletion of srr1 increased GBS fitness in whole blood.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18707,PHI:11574,UniProt,A0A0G2Z8C7,GenBank,AKI95824,,,SS1,srr1,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood plasma,serine-rich repeat 1 glycoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,Deletion of srr1 increased GBS fitness in whole blood.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18708,PHI:11575,UniProt,Q8DYL2,GenBank,AE014259_6,,,2603V/R,1478,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood; blood plasma,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,Deletion of srr1 increased GBS fitness in whole blood.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18709,PHI:11576,UniProt,Q8DYL6,GenBank,AE014259_2,,,2603V/R,uvrB,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood; blood plasma,"excinuclease ABC, B subunit",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,Deletion of srr1 increased GBS fitness in whole blood.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18710,PHI:11577,UniProt,Q8DYL9,GenBank,AE014258_15,,,2603V/R,1460,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood; blood plasma,"glycosyl transferase, family 8",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,Deletion of srr1 increased GBS fitness in whole blood.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18711,PHI:11578,UniProt,Q8DYM0,GenBank,AE014258_14,,,2603V/R,1459,,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood; blood plasma,"glycosyl transferase, family 8",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,32747604,PubMed,10.1128/IAI.00357-20,Infect Immun. 2020 Sep 18;88(10):e00357-20,lzhu2@houstonmethodist.org,Deletion of srr1 increased GBS fitness in whole blood.,L Zhu 2020,2020,9 genes,Zhu-2020-Genome-wide assessment of Streptococc,BATCH_107B,2021-08-01,MC,,,,,,,,,,,,,
,,Record 18712,PHI:11579,UniProt,O15721,GenBank,AAB69693,,,ME49,P18,,,,,,,5811,Toxoplasma gondii,1080348,PruΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneum; spleen,surface antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34262559,PubMed,10.3389/fimmu.2021.643292,Front Immunol. 2021 Jun 28;12:643292,he21@aub.edu.lb,"Deletion of P18 gene impaired the invasion of parasites in macrophages and IFN-g mediated activation of macrophages further reduced the invasion capacity of this KO, as compared to WT strain.",M Hamie 2021,2021,1 gene,Hamie-2021-P18 (SRS35_TgSAG4) Plays a Role in,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18713,PHI:11579,UniProt,O15721,GenBank,AAB69693,,,ME49,P18,,,,,,,5811,Toxoplasma gondii,1080348,PruΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,surface antigen,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34262559,PubMed,10.3389/fimmu.2021.643292,Front Immunol. 2021 Jun 28;12:643292,he21@aub.edu.lb,"Deletion of P18 gene impaired the invasion of parasites in macrophages and IFN-g mediated activation of macrophages further reduced the invasion capacity of this KO, as compared to WT strain.",M Hamie 2021,2021,1 gene,Hamie-2021-P18 (SRS35_TgSAG4) Plays a Role in,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18714,PHI:11579,UniProt,O15721,GenBank,AAB69693,,,ME49,P18,,,,,,,5811,Toxoplasma gondii,1080348,PruΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,surface antigen,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34262559,PubMed,10.3389/fimmu.2021.643292,Front Immunol. 2021 Jun 28;12:643292,he21@aub.edu.lb,"Deletion of P18 gene impaired the invasion of parasites in macrophages and IFN-g mediated activation of macrophages further reduced the invasion capacity of this KO, as compared to WT strain.",M Hamie 2021,2021,1 gene,Hamie-2021-P18 (SRS35_TgSAG4) Plays a Role in,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18715,PHI:11580,UniProt,A3RQ96,GenBank,EAP74236,,,UW551,ripS1,,UW551-TnR1 (transposon inserted in an intergenic region between a type III secretion system effector gene ripS1 and a major facilitator superfamily (MFS) protein gene),,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,YVS,34367225,PubMed,10.3389/fpls.2021.705717,Front Plant Sci. 2021 Jul 22;12:705717,qi.huang@usda.gov,"The mutant strain was unaltered compared to the wild-type strain for flagellar motility, twitching motility, or susceptibility to exogenous hydrogen peroxide, regardless of whether grown at 20 or 28°C.",J K Schachterle 2021,2021,1 gene,Schachterle-2021-Implication of the Type III E,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18716,PHI:11581,UniProt,G4MY57,GenBank,EHA54388,,,70-15,Mowhi2 (MGG_11241),chromosome 2,,,Mopsr1 (MGG_03646),UniProt: G4N711; GenBank: EHA49924,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,general stress response protein,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,,no,sodium dodecyl sulphate (SDS); sorbitol; H2O2; menadione,sodium dodecyl sulphate (SDS): CHEBI:8984; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,34036714,PubMed,10.1111/mpp.13074,Mol Plant Pathol. 2021 Aug;22(8):969-983,kouyanjun@caas.cn,Inappropriate activation of the MoTor signalling pathway was one of the important reasons for the defects in appressorium formation in the ΔMowhi2 and ΔMopsr1 strains.,H Shi 2021,2021,2 genes,Shi-2021-MoWhi2 regulates appressorium formati,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18717,PHI:11582,UniProt,G4N711,GenBank,EHA49924,,,70-15,Mopsr1 (MGG_03646),chromosome 4,,,Mowhi2 (MGG_11241),UniProt: G4MY57; GenBank: EHA54388,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,serine/threonine-protein phosphatase dullard,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,,no,sodium dodecyl sulphate (SDS); sorbitol; H2O2; menadione,sodium dodecyl sulphate (SDS): CHEBI:8984; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,34036714,PubMed,10.1111/mpp.13074,Mol Plant Pathol. 2021 Aug;22(8):969-983,kouyanjun@caas.cn,Inappropriate activation of the MoTor signalling pathway was one of the important reasons for the defects in appressorium formation in the ΔMowhi2 and ΔMopsr1 strains.,H Shi 2021,2021,2 genes,Shi-2021-MoWhi2 regulates appressorium formati,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18718,PHI:11583,UniProt,G4MMY4,GenBank,EHA57006,,,70-15,MoGLN1 (MGG_06888),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: Rice),cv. CO-39,,,leaf,glutamine synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white (CFW); sodium dodecyl sulfate (SDS); Congo red (CR); hydrogen peroxide (H2O2),calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red (CR): CHEBI:34653; hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34201222,PubMed,10.3390/jof7060463,J Fungi (Basel). 2021 Jun 8;7(6):463,wangzh@fafu.edu.cn,"MoGLN2 was important for vegetative growth, conidiation, appressorium formation, maintenance of cell wall integrity, oxidative stress tolerance and pathogenesis of M. oryzae.",O Aron 2021,2021,3 genes,Aron-2021-MoGLN2 Is Important for Vegetative G,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18719,PHI:11584,UniProt,G4NG12,GenBank,EHA46969,,,70-15,MoGLN2 (MGG_14279),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: Rice),cv. CO-39,,,leaf,glutamine synthetase,,,,loss of pathogenicity,,yes,yes,,,reduced,,reduced,,no,calcofluor white (CFW); sodium dodecyl sulfate (SDS); Congo red (CR); hydrogen peroxide (H2O2),calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red (CR): CHEBI:34653; hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34201222,PubMed,10.3390/jof7060463,J Fungi (Basel). 2021 Jun 8;7(6):463,wangzh@fafu.edu.cn,"MoGLN2 was important for vegetative growth, conidiation, appressorium formation, maintenance of cell wall integrity, oxidative stress tolerance and pathogenesis of M. oryzae.",O Aron 2021,2021,3 genes,Aron-2021-MoGLN2 Is Important for Vegetative G,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18720,PHI:11585,UniProt,G5EHD8,GenBank,EHA46521,,,70-15,MoGLN3 (MGG_02538),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: Rice),cv. CO-39,,,leaf,glutamine synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white (CFW); sodium dodecyl sulfate (SDS); Congo red (CR); hydrogen peroxide (H2O2),calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red (CR): CHEBI:34653; hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34201222,PubMed,10.3390/jof7060463,J Fungi (Basel). 2021 Jun 8;7(6):463,wangzh@fafu.edu.cn,"MoGLN2 was important for vegetative growth, conidiation, appressorium formation, maintenance of cell wall integrity, oxidative stress tolerance and pathogenesis of M. oryzae.",O Aron 2021,2021,3 genes,Aron-2021-MoGLN2 Is Important for Vegetative G,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18721,PHI:11583,UniProt,G4MMY4,GenBank,EHA57006,,,70-15,MoGLN1 (MGG_06888),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: Barley),,,,leaf,glutamine synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white (CFW); sodium dodecyl sulfate (SDS); Congo red (CR); hydrogen peroxide (H2O2),calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red (CR): CHEBI:34653; hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34201222,PubMed,10.3390/jof7060463,J Fungi (Basel). 2021 Jun 8;7(6):463,wangzh@fafu.edu.cn,"MoGLN2 was important for vegetative growth, conidiation, appressorium formation, maintenance of cell wall integrity, oxidative stress tolerance and pathogenesis of M. oryzae.",O Aron 2021,2021,3 genes,Aron-2021-MoGLN2 Is Important for Vegetative G,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18722,PHI:11584,UniProt,G4NG12,GenBank,EHA46969,,,70-15,MoGLN2 (MGG_14279),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: Barley),,,,leaf,glutamine synthetase,,,,loss of pathogenicity,,yes,yes,,,reduced,,reduced,,no,calcofluor white (CFW); sodium dodecyl sulfate (SDS); Congo red (CR); hydrogen peroxide (H2O2),calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red (CR): CHEBI:34653; hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34201222,PubMed,10.3390/jof7060463,J Fungi (Basel). 2021 Jun 8;7(6):463,wangzh@fafu.edu.cn,"MoGLN2 was important for vegetative growth, conidiation, appressorium formation, maintenance of cell wall integrity, oxidative stress tolerance and pathogenesis of M. oryzae.",O Aron 2021,2021,3 genes,Aron-2021-MoGLN2 Is Important for Vegetative G,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18723,PHI:11585,UniProt,G5EHD8,GenBank,EHA46521,,,70-15,MoGLN3 (MGG_02538),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: Barley),,,,leaf,glutamine synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,calcofluor white (CFW); sodium dodecyl sulfate (SDS); Congo red (CR); hydrogen peroxide (H2O2),calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red (CR): CHEBI:34653; hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34201222,PubMed,10.3390/jof7060463,J Fungi (Basel). 2021 Jun 8;7(6):463,wangzh@fafu.edu.cn,"MoGLN2 was important for vegetative growth, conidiation, appressorium formation, maintenance of cell wall integrity, oxidative stress tolerance and pathogenesis of M. oryzae.",O Aron 2021,2021,3 genes,Aron-2021-MoGLN2 Is Important for Vegetative G,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18724,PHI:11586,UniProt,A0A0D1E2L4,GenBank,KIS68845,,,521,Tec1 (UMAG_02835),chromosome 7,,,,,,5270,Ustilago maydis,559306,FB1,smut,monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,seedling,TEA transcription factor,,,,loss of pathogenicity,yes,,,,,,reduced,,,no,sorbitol; H2O2; NaCl; KCl; LiCl,sorbitol: CHEBI:17924; H2O2: CHEBI:16240; NaCl: CHEBI:267101; KCl: CHEBI:32588; LiCl: CHEBI:48607,,,,,gene deletion: full; gene complementation,,,YVS,34185162,PubMed,10.1007/s10123-021-00188-8,Int Microbiol. 2021 Jun 29,jose.ruiz@cinvestav.mx,"Tec1 was found to be a crucial factor for normal mating, basidiocarp development, and virulence, all of the functions related to the dikaryotic stage dependent of the b genes, whereas dimorphism and resistance to different stress conditions occurring in the haploid stage were not affected in tec1 mutants.",C G León-Ramírez 2021,2021,1 gene,"León-Ramírez-2021-Tec1, a member of the TEA tr",BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18725,PHI:11586,UniProt,A0A0D1E2L4,GenBank,KIS68845,,,521,Tec1 (UMAG_02835),chromosome 7,,,,,,5270,Ustilago maydis,,FB2,smut,monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,seedling,TEA transcription factor,,,,loss of pathogenicity,yes,,,,,,reduced,,,no,sorbitol; H2O2; NaCl; KCl; LiCl,sorbitol: CHEBI:17924; H2O2: CHEBI:16240; NaCl: CHEBI:267101; KCl: CHEBI:32588; LiCl: CHEBI:48607,,,,,gene deletion: full; gene complementation,,,YVS,34185162,PubMed,10.1007/s10123-021-00188-8,Int Microbiol. 2021 Jun 29,jose.ruiz@cinvestav.mx,"Tec1 was found to be a crucial factor for normal mating, basidiocarp development, and virulence, all of the functions related to the dikaryotic stage dependent of the b genes, whereas dimorphism and resistance to different stress conditions occurring in the haploid stage were not affected in tec1 mutants.",C G León-Ramírez 2021,2021,1 gene,"León-Ramírez-2021-Tec1, a member of the TEA tr",BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18726,PHI:11587,UniProt,A0A0J9U9A1,GenBank,KNA95397,,,4287,Fotip4 (FOXG_00980),chromosome 1,,,,,,5507,Fusarium oxysporum,,,vascular wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. Chongqing,,,leaf; tuber,C2H2-type domain-containing protein,,,,reduced virulence,,,yes,yes,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34288333,PubMed,10.1111/mpp.13108,Mol Plant Pathol. 2021 Oct;22(10):1239-1255,renmaozhi01@caas.cn,FoTOR signalling was involved in the regulation of CWDEs through FoTIP4 in F. oxysporum.,L Li 2021,2021,1 gene,Li-2021-Target of rapamycin controls hyphal gr,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18727,PHI:11588,UniProt,A0A1B2RBP7,GenBank,,,,,PPECC33_0249 (Rhs1),,,,,,,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18728,PHI:11589,UniProt,no data found,GenBank,,,,,PPECC33_1589 (Rhs2),,,,,,,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18729,PHI:11590,UniProt,no data found,GenBank,,,,,PPECC33_0721 (Rhs3),,,,,,,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18730,PHI:11591,UniProt,no data found,GenBank,,,,,PPECC33_2154 (Rhs4),,,,,,,562,Escherichia coli,1001989,PCN033,infection,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18731,PHI:11588,UniProt,A0A1B2RBP7,GenBank,,,,,PPECC33_0249 (Rhs1),,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),Kunming,,,blood; brain; lung; spleen,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18732,PHI:11589,UniProt,no data found,GenBank,,,,,PPECC33_1589 (Rhs2),,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),Kunming,,,blood; brain; lung; spleen,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18733,PHI:11590,UniProt,no data found,GenBank,,,,,PPECC33_0721 (Rhs3),,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),Kunming,,,blood; brain; lung; spleen,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18734,PHI:11591,UniProt,no data found,GenBank,,,,,PPECC33_2154 (Rhs4),,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),Kunming,,,blood; brain; lung; spleen,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18735,PHI:11588,UniProt,A0A1B2RBP7,GenBank,,,,,PPECC33_0249 (Rhs1),,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18736,PHI:11589,UniProt,no data found,GenBank,,,,,PPECC33_1589 (Rhs2),,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18737,PHI:11590,UniProt,no data found,GenBank,,,,,PPECC33_0721 (Rhs3),,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18738,PHI:11591,UniProt,no data found,GenBank,,,,,PPECC33_2154 (Rhs4),,,,,,,562,Escherichia coli,1001989,PCN033,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,classic rearrangement hotspot protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34382147,PubMed,10.1007/s12275-021-1189-2,J Microbiol. 2021 Sep;59(9):854-860,tanchen@mail.hzau.edu.cn,"Animal infection experiments showed that the Δrhs-1CT, Δrhs-2CT, Δrhs-3CT, and Δrhs-4CT caused a significant decrease in the multiplication ability of PCN033 in vivo.",W Lu 2021,2021,4 genes,Lu-2021-Function of Rhs proteins in porcine ex,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18739,PHI:11592,UniProt,Q0SZB7,GenBank,ABF05598,,,8401,yhjC,,,,,,,623,Shigella flexneri,,M90T,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34152261,PubMed,10.1080/21505594.2021.1936767,Virulence. 2021 Dec;12(1):1661-1671,lihuiying0711@163.com,"Pathogenicity of the yhjC mutant, including colonization in the colons of guinea pigs as well as its ability for host cell adhesion and invasion, was significantly lowered.",W Li 2021,2021,1 gene,Li-2021-YhjC is a novel transcriptional regula,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18740,PHI:11592,UniProt,Q0SZB7,GenBank,ABF05598,,,8401,yhjC,,,,,,,623,Shigella flexneri,,M90T,shigellosis,rodents,10141,Cavia porcellus (related: Domestic Guinea pig),Duncan-Hartley,,,colon,LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34152261,PubMed,10.1080/21505594.2021.1936767,Virulence. 2021 Dec;12(1):1661-1671,lihuiying0711@163.com,"Pathogenicity of the yhjC mutant, including colonization in the colons of guinea pigs as well as its ability for host cell adhesion and invasion, was significantly lowered.",W Li 2021,2021,1 gene,Li-2021-YhjC is a novel transcriptional regula,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18741,PHI:11593,UniProt,G4MVB1,GenBank,EHA54933,,,70-15,MoCpa1 (MGG_01743),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: Rice),cv. CO-39,,,leaf,carbamoyl-phosphate synthase subunit arginine-specific small,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced; aberrant,,no,calcofluor white (CFW); sodium dodecyl sulfate (SDS); Congo red (CR); NaCl,calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red (CR): CHEBI:34653; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,34292355,PubMed,10.1007/s00253-021-11437-1,Appl Microbiol Biotechnol. 2021 Aug;105(14-15):5915-5929,tangw@fafu.edu.cn,"The ΔMocpa1 mutant was nonpathogenic on rice and barley leaves, which was a result of defects in appressorium-mediated penetration and restricted invasive hyphal growth within host cells.",O Aron 2021,2021,1 gene,Aron-2021-MoCpa1-mediated arginine biosynthesi,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18742,PHI:11593,UniProt,G4MVB1,GenBank,EHA54933,,,70-15,MoCpa1 (MGG_01743),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: Barley),,,,leaf,carbamoyl-phosphate synthase subunit arginine-specific small,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced; aberrant,,no,calcofluor white (CFW); sodium dodecyl sulfate (SDS); Congo red (CR); NaCl,calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red (CR): CHEBI:34653; NaCl: CHEBI:267101,,,,,gene deletion: full; gene complementation,,,YVS,34292355,PubMed,10.1007/s00253-021-11437-1,Appl Microbiol Biotechnol. 2021 Aug;105(14-15):5915-5929,tangw@fafu.edu.cn,"The ΔMocpa1 mutant was nonpathogenic on rice and barley leaves, which was a result of defects in appressorium-mediated penetration and restricted invasive hyphal growth within host cells.",O Aron 2021,2021,1 gene,Aron-2021-MoCpa1-mediated arginine biosynthesi,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18743,PHI:11594,UniProt,I1RIT1,GenBank,CEF78581,,,PH-1,FgMFS1 (FGSG_03725),chromosome 2,,,,,,5518,Fusarium graminearum,,DAOM 180378,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Roblin,,,inflorescence,major facilitator superfamily (MFS) transporter,,,,reduced virulence,,,,,,,,,,no,salicylic acid,salicylic acid: CHEBI:16914,,,,,gene deletion: full; gene complementation,,,YVS,34445203,PubMed,10.3390/ijms22168497,Int J Mol Sci. 2021 Aug 7;22(16):8497,pengfeiqi@hotmail.com,"ΔFgMFS1 (loss of function mutant of FgMFS1) showed enhanced sensitivity to SA, less pathogenicity towards wheat, and reduced DON production under SA stress.",Q Chen 2021,2021,1 gene,Chen-2021-Major Facilitator Superfamily Transp,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18744,PHI:11595,UniProt,A8ULG6,GenBank,ABW71134,,,EHE-NE18,netB,,,,,,,1502,Clostridium perfringens,,EHE-NE18,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),,,,erythrocyte,necrotic enteritis toxin B precursor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34442787,PubMed,10.3390/microorganisms9081708,Microorganisms. 2021 Aug 11;9(8):1708,Evy.Goossens@UGent.be,"The NetB mutant induced significantly less haemolysis compared to the alpha toxin mutant and the NE18 wild-type strain, suggesting that most haemolysis was indeed caused by NetB.",M Hustá 2021,2021,2 genes,Hustá-2021-A Rapid and Simple Assay Correlates,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18745,PHI:11596,UniProt,A8II73,GenBank,AKA95488,,,cdio_ET_02,cpa,,,,,,,1502,Clostridium perfringens,,EHE-NE18,necrotic enteritis,birds,9031,Gallus gallus (related: chicken),,,,erythrocyte,alpha-toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34442787,PubMed,10.3390/microorganisms9081708,Microorganisms. 2021 Aug 11;9(8):1708,Evy.Goossens@UGent.be,"The NetB mutant induced significantly less haemolysis compared to the alpha toxin mutant and the NE18 wild-type strain, suggesting that most haemolysis was indeed caused by NetB.",M Hustá 2021,2021,2 genes,Hustá-2021-A Rapid and Simple Assay Correlates,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18746,PHI:11597,UniProt,J4KP58,GenBank,EJP66879,,,ARSEF 2860,csn5,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemolymph,subunit ofthe COP9/signalosome complex,,,,reduced virulence,,,yes,,,reduced,,reduced; aberrant,reduced,no,calcofluor white (CFW); Congo red (CR); sorbitol; H2O2; NaCl; menadione,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:17924; H2O2: CHEBI:16240; NaCl: CHEBI:267101; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,YVS,34436181,PubMed,10.3390/jof7080642,J Fungi (Basel). 2021 Aug 7;7(8):642,mgfeng@zju.edu.cn,"Deletion mutant displayed abolished insect pathogenicity, marked reductions in conidial hydrophobicity and adherence to the insect cuticle, the abolished secretion of cuticle penetration-required enzymes, blocked haemocoel colonisation, and reduced conidiation capacity despite unaffected biomass accumulation.",Y N Mou 2021,2021,1 gene,Mou-2021-Essential Role of COP9 Signalosome Su,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18747,PHI:11598,UniProt,A0A0D1D169,GenBank,UMAG00538,,,,vp1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Honey 236; cv. Early Golden Bantam,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34436129,PubMed,10.3390/jof7080589,J Fungi (Basel). 2021 Jul 23;7(8):589,laysunma@gate.sinica.edu.tw,The reduction in fungal virulence and colonization in the vp1 mutant suggested the virulence-promoting function of Vp1.,C V Hoang 2021,2021,1 gene,Hoang-2021-A Novel Core Effector Vp1 Promotes,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18748,PHI:11599,UniProt,A0A0H2X5C4,GenBank,AAY48424,,,8004,XC_1355 (hlp),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,DNA-binding histone-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,sodium dodecyl sulfate (SDS); H2O2; NaCl; phenol; CdCl2; CuSO4; ZnSO4,sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:26710; phenol: CHEBI:15882; CdCl2: CHEBI:35456; CuSO4: CHEBI:23414; ZnSO4: CHEBI:35176,,,,,gene deletion: full; gene complementation,,,YVS,34424610,PubMed,10.1111/mpp.13128,Mol Plant Pathol. 2021 Aug 23,lugt@gxu.edu.cn,"Mutation of XC_1355 in Xcc reduced the virulence, extracellular polysaccharide production, and cell motility.",Q Su 2021,2021,2 genes,Su-2021-A HU-like protein is required for full,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18749,PHI:11599,UniProt,A0A0H2X5C4,GenBank,AAY48424,,,8004,XC_1355 (hlp),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),,,,leaf,DNA-binding histone-like protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); H2O2; NaCl; phenol; CdCl2; CuSO4; ZnSO4,sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:26710; phenol: CHEBI:15882; CdCl2: CHEBI:35456; CuSO4: CHEBI:23414; ZnSO4: CHEBI:35176,,,,,gene deletion: full; gene complementation,,,YVS,34424610,PubMed,10.1111/mpp.13128,Mol Plant Pathol. 2021 Aug 23,lugt@gxu.edu.cn,"Mutation of XC_1355 in Xcc reduced the virulence, extracellular polysaccharide production, and cell motility.",Q Su 2021,2021,2 genes,Su-2021-A HU-like protein is required for full,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18750,PHI:11600,UniProt,A0A0H2X4X9,GenBank,AAY47601,,,8004,XC_0520 (flp),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),,,,leaf,Fis family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); H2O2; NaCl; phenol; CdCl2; CuSO4; ZnSO4,sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:26710; phenol: CHEBI:15882; CdCl2: CHEBI:35456; CuSO4: CHEBI:23414; ZnSO4: CHEBI:35176,,,,,gene deletion: full; gene complementation,,,YVS,34424610,PubMed,10.1111/mpp.13128,Mol Plant Pathol. 2021 Aug 23,lugt@gxu.edu.cn,Overexpression of XC_1355 in the flp deletion mutant Δflp partially restored the virulence towards wild type.,Q Su 2021,2021,2 genes,Su-2021-A HU-like protein is required for full,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18751,PHI:11601,UniProt,A0A0E0SID1,GenBank,CEF86194,,,PH-1,sah1 (FGSG_05615),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 5,,,inflorescence,S-adenosyl-L-homocysteine hydrolase,,,,reduced virulence,,,yes,,,reduced,reduced,reduced,reduced,no,Congo red (CR); sodium dodecyl sulphate (SDS); H2O2; NaCl; KCl; fludioxonil; iprodione,Congo red (CR): CHEBI:34653; sodium dodecyl sulphate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101; KCl: CHEBI:32588; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909,,,,,gene deletion: full; gene complementation,,,YVS,34424830,PubMed,10.1080/21505594.2021.1965821,Virulence. 2021 Dec;12(1):2171-2185,mahongyu@njau.edu.cn,"Deletion of FgSAH1 resulted in defects in vegetative growth, asexual and sexual reproduction, stress responses, virulence, lipid metabolism, and tolerance against fungicides.",D Shi 2021,2021,1 gene,Shi-2021-S-adenosyl-L-homocysteine hydrolase F,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18752,PHI:11602,UniProt,Q8ZLB5,GenBank,CAC86200,,,LT2,bcsE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain DMC2,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,cyclic di-GMP binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34279609,PubMed,10.1093/femspd/ftab037,Pathog Dis. 2021 Jul 28;79(6):ftab037,akcelik@science.ankara.edu.tr,Systemic persistence in the liver and spleen samples decreased by 99.99% and 100% in the bcsE mutant strains.,C Ozdemir 2021,2021,1 gene,Özdemir-2021-The role of bcsE gene in the path,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18753,PHI:11602,UniProt,Q8ZLB5,GenBank,CAC86200,,,LT2,bcsE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain DMC2,infection,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,enterocyte,cyclic di-GMP binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34279609,PubMed,10.1093/femspd/ftab037,Pathog Dis. 2021 Jul 28;79(6):ftab037,akcelik@science.ankara.edu.tr,The invasion abilities on HT-29 epithelial cells of wild-type strains were utterly disappeared in their bcsE gene mutant strains.,C Ozdemir 2021,2021,1 gene,Özdemir-2021-The role of bcsE gene in the path,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18754,PHI:11602,UniProt,Q8ZLB5,GenBank,CAC86200,,,LT2,bcsE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain DMC4,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,cyclic di-GMP binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34279609,PubMed,10.1093/femspd/ftab037,Pathog Dis. 2021 Jul 28;79(6):ftab037,akcelik@science.ankara.edu.tr,Systemic persistence in the liver and spleen samples decreased by 99.99% and 100% in the bcsE mutant strains.,C Ozdemir 2021,2021,1 gene,Özdemir-2021-The role of bcsE gene in the path,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18755,PHI:11602,UniProt,Q8ZLB5,GenBank,CAC86200,,,LT2,bcsE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain DMC4,infection,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,enterocyte,cyclic di-GMP binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34279609,PubMed,10.1093/femspd/ftab037,Pathog Dis. 2021 Jul 28;79(6):ftab037,akcelik@science.ankara.edu.tr,The invasion abilities on HT-29 epithelial cells of wild-type strains were utterly disappeared in their bcsE gene mutant strains.,C Ozdemir 2021,2021,1 gene,Özdemir-2021-The role of bcsE gene in the path,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18756,PHI:11603,UniProt,A0A1L2DC29,GenBank,ANA91018,,,,VmGlu2,,,,,,,105487,Valsa mali,,LXS080601,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf,beta-glucosidase,,,,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34394036,PubMed,10.3389/fmicb.2021.695112,Front Microbiol. 2021 Jul 30;12:695112,cxwang@qau.edu.cn,The gene deletion mutants had lower beta-glucosidase activities and toxin levels as compared to the wild-type strain.,Y Huang 2021,2021,1 gene,Huang-2021-ß-Glucosidase VmGlu2 Contributes to,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18757,PHI:11603,UniProt,A0A1L2DC29,GenBank,ANA91018,,,,VmGlu2,,,,,,,105487,Valsa mali,,LXS080601,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf,beta-glucosidase,,,,increased virulence (hypervirulence),,,,,,reduced,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34394036,PubMed,10.3389/fmicb.2021.695112,Front Microbiol. 2021 Jul 30;12:695112,cxwang@qau.edu.cn,The gene deletion mutants had lower beta-glucosidase activities and toxin levels as compared to the wild-type strain.,Y Huang 2021,2021,1 gene,Huang-2021-ß-Glucosidase VmGlu2 Contributes to,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18758,PHI:11604,UniProt,P0A2M9,GenBank,AAL23529,,,LT2,spvC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain STM,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,phosphothreonine lyase,,,,reduced virulence,,,,,,,,,,no,bafilomycin A1,bafilomycin A1: CHEBI:22689,,,,,gene deletion: full; gene complementation,,,YVS,34335562,PubMed,10.3389/fimmu.2021.639019,Front Immunol. 2021 Jul 14;12:639019,wushuyan@suda.edu.cn,SpvC inhibited autophagosome formation through its phosphothreonine lyase activity.,L Zhou 2021,2021,1 gene,Zhou-2021-Salmonella spvC Gene Inhibits Autoph,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18759,PHI:11604,UniProt,P0A2M9,GenBank,AAL23529,,,LT2,spvC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain STM,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,phosphothreonine lyase,,,,reduced virulence,,,,,,,,,,no,bafilomycin A1,bafilomycin A1: CHEBI:22689,,,,,gene deletion: full; gene complementation,,,YVS,34335562,PubMed,10.3389/fimmu.2021.639019,Front Immunol. 2021 Jul 14;12:639019,wushuyan@suda.edu.cn,SpvC inhibited autophagosome formation through its phosphothreonine lyase activity.,L Zhou 2021,2021,1 gene,Zhou-2021-Salmonella spvC Gene Inhibits Autoph,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18760,PHI:11605,UniProt,P37195,GenBank,AAC76532,,,K-12,dctR,,,,,,,562,Escherichia coli,,CE08,avian colibacillosis,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; spleen,putative DNA-binding transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34229767,PubMed,10.1186/s13567-021-00970-6,Vet Res. 2021 Jul 6;52(1):101,shwang0827@126.com,"Inactivation of the dctR gene led to decreased biofilm formation, diminished serum resistance, reduced adherence capacity, attenuated colonization and virulence of APEC in ducks.",Y Zhang 2021,2021,1 gene,Zhang-2021-DctR contributes to the virulence o,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18761,PHI:11605,UniProt,P37195,GenBank,AAC76532,,,K-12,dctR,,,,,,,562,Escherichia coli,,CE08,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,UMNSAH/DF-1 cell,putative DNA-binding transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34229767,PubMed,10.1186/s13567-021-00970-6,Vet Res. 2021 Jul 6;52(1):101,shwang0827@126.com,DctR promoted the adhesion of CE08 to DF-1 cells.,Y Zhang 2021,2021,1 gene,Zhang-2021-DctR contributes to the virulence o,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18762,PHI:11606,UniProt,G2X4G0,GenBank,,,,,Vd424Y,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Jimian 11,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34233072,PubMed,10.1111/mpp.13100,Mol Plant Pathol. 2021 Sep;22(9):1109-1120,gexiaoyang@caas.cn,Vd424Y could promoted V. dahliae infection.,L Liu 2021,2021,1 gene,Liu-2021-Verticillium dahliae secreted protein,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18763,PHI:11606,UniProt,G2X4G0,GenBank,,,,,Vd424Y,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,other evidence: transgenic plants,,,YVS,34233072,PubMed,10.1111/mpp.13100,Mol Plant Pathol. 2021 Sep;22(9):1109-1120,gexiaoyang@caas.cn,Vd424Y could promoted V. dahliae infection.,L Liu 2021,2021,1 gene,Liu-2021-Verticillium dahliae secreted protein,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18764,PHI:11607,UniProt,G4YNY4,GenBank,EGZ30744,,,P6497,PsFP1,,,,,,,67593,Phytophthora sojae,1094619,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,seedling,FYVE zinc-finger domain containing protein,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34202990,PubMed,10.3390/ijms22126601,Int J Mol Sci. 2021 Jun 20;22(12):6601,mjq2018@nwafu.edu.cn,The PsFP1 mutants showed a decrease in mycelial growth and pathogenicity and were more sensitive to hydrogen peroxide.,J Zhang 2021,2021,2 genes,Zhang-2021-An FYVE-Domain-Containing Protein,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18765,PHI:11608,UniProt,G4YW94,GenBank,EGZ24984,,,P6497,PsFP2,,,,,,,67593,Phytophthora sojae,1094619,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,seedling,FYVE zinc-finger domain containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34202990,PubMed,10.3390/ijms22126601,Int J Mol Sci. 2021 Jun 20;22(12):6601,mjq2018@nwafu.edu.cn,The PsFP1 mutants showed a decrease in mycelial growth and pathogenicity and were more sensitive to hydrogen peroxide.,J Zhang 2021,2021,2 genes,Zhang-2021-An FYVE-Domain-Containing Protein,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18766,PHI:11609,UniProt,Q8ZNK8,GenBank,AAL21105,,,LT2,yeiE,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA420,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; large intestine,putative LysR family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34098734,PubMed,10.1128/mBio.03680-20,mBio. 2021 Jun 29;12(3):e0368020,jelfenbein@wisc.edu,The transcriptional regulator YeiE acted as a control point for flagellar gene expression and was required for Salmonella Typhimurium to establish a productive infection in mammals.,T L Westerman 2021,2021,3 genes,Westerman-2021-YeiE Regulates Motility and Gut,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18767,PHI:11610,UniProt,P06179,GenBank,AAL20871,,,LT2,fliC,,,,,,PHI:11611,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA420,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; large intestine,flagellar biosynthesis; flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34098734,PubMed,10.1128/mBio.03680-20,mBio. 2021 Jun 29;12(3):e0368020,jelfenbein@wisc.edu,The transcriptional regulator YeiE acted as a control point for flagellar gene expression and was required for Salmonella Typhimurium to establish a productive infection in mammals.,T L Westerman 2021,2021,3 genes,Westerman-2021-YeiE Regulates Motility and Gut,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18768,PHI:11611,UniProt,P52616,GenBank,AAL21657,,,LT2,fljB,,,,,,PHI:11610,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA420,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; large intestine,filament structural protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34098734,PubMed,10.1128/mBio.03680-20,mBio. 2021 Jun 29;12(3):e0368020,jelfenbein@wisc.edu,The transcriptional regulator YeiE acted as a control point for flagellar gene expression and was required for Salmonella Typhimurium to establish a productive infection in mammals.,T L Westerman 2021,2021,3 genes,Westerman-2021-YeiE Regulates Motility and Gut,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18769,PHI:11609,UniProt,Q8ZNK8,GenBank,AAL21105,,,LT2,yeiE,,,,,,PHI:11610; PHI:11611,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA420,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; large intestine,putative LysR family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34098734,PubMed,10.1128/mBio.03680-20,mBio. 2021 Jun 29;12(3):e0368020,jelfenbein@wisc.edu,The transcriptional regulator YeiE acted as a control point for flagellar gene expression and was required for Salmonella Typhimurium to establish a productive infection in mammals.,T L Westerman 2021,2021,3 genes,Westerman-2021-YeiE Regulates Motility and Gut,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18770,PHI:11610,UniProt,P06179,GenBank,AAL20871,,,LT2,fliC,,,,,,PHI:11609; PHI:11611,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA420,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; large intestine,flagellar biosynthesis; flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34098734,PubMed,10.1128/mBio.03680-20,mBio. 2021 Jun 29;12(3):e0368020,jelfenbein@wisc.edu,The transcriptional regulator YeiE acted as a control point for flagellar gene expression and was required for Salmonella Typhimurium to establish a productive infection in mammals.,T L Westerman 2021,2021,3 genes,Westerman-2021-YeiE Regulates Motility and Gut,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18771,PHI:11611,UniProt,P52616,GenBank,AAL21657,,,LT2,fljB,,,,,,PHI:11609; PHI:11610,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain HA420,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; large intestine,filament structural protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34098734,PubMed,10.1128/mBio.03680-20,mBio. 2021 Jun 29;12(3):e0368020,jelfenbein@wisc.edu,The transcriptional regulator YeiE acted as a control point for flagellar gene expression and was required for Salmonella Typhimurium to establish a productive infection in mammals.,T L Westerman 2021,2021,3 genes,Westerman-2021-YeiE Regulates Motility and Gut,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18772,PHI:11612,UniProt,A0A384JS06,GenBank,ATZ53375,,,B05.10,Bmp3,BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romana,,,leaf,Slt2-type MAP kinase,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34069750,PubMed,10.3390/ijms22105362,Int J Mol Sci. 2021 May 19;22(10):5362,susanna.pecchia@unipi.it,"Topical applications of dsRNA led to gene knockdown with a delay in conidial germination, an evident growth retardation and a strong reduction of necrotic lesions on leaves.",M Spada 2021,2021,1 gene,Spada-2021-Silencing of the Slt2-Type MAP Kina,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18773,PHI:11613,UniProt,no data found,GenBank,,,,,Bbmsn2,,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,mites and ticks,6941,Rhipicephalus microplus (related: southern cattle tick),,,,cuticle,stress–response transcription factor,,,,reduced virulence,,no,,,,,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34354961,PubMed,10.3389/fcimb.2021.690731,Front Cell Infect Microbiol. 2021 Jul 20;11:690731,evertonkort@ufg.br,"The Msn2 transcription factor reduced B. bassiana virulence against R. microplus, but did not interfere with conidial germination, appressoria formation or sporulation on tick cadavers, and played only a minimal role once the cuticle is breached.",E R Muniz 2021,2021,1 gene,Muniz-2021-The Msn2 Transcription Factor Regul,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18774,PHI:11614,UniProt,A0A0H3LHX7,GenBank,CAE31223,,,RB50,cyaB (bb0723),,,,,,,139,Borreliella burgdorferi,,B31 5A4 NP1,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,lymph node; ear; skin; bladder,non-toxin class IV adenylate cyclase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34113333,PubMed,10.3389/fmicb.2021.676192,Front Microbiol. 2021 May 25;12:676192,jhyde@tamu.edu,B. burgdorferi utilized cyaB and potentially cAMP as a regulatory pathway to modulate borrelial gene expression and protein production to promote borrelial virulence and dissemination in the mammalian host.,V M Ante 2021,2021,1 gene,Ante-2021-The Borrelia burgdorferi Adenylate C,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18775,PHI:11615,UniProt,A0A384JPH0,GenBank,ATZ52410,,,B05.10,Bcgb1 (Bcin08g01420),BCIN08,,,BcSte11 (Bcin03g02630); BcBck1 (Bcin02g06590); BcMkk1 (Bcin03g07190); BcSte50 (Bcin08g03660),UniProt: A0A384JBK1; GenBank: ATZ47995; UniProt: A0A384JA56; GenBank: ATZ47370; UniProt: A0A,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,G protein beta subunit protein,,,,reduced virulence,,,,yes,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulphate (SDS); H2O2; NaCl; KCl; sorbitol; sucrose,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulphate (SDS): CHEBI:8984; H2O2: CHEBI:16240; NaCl: CHEBI:267101; KCl: CHEBI:32588; sorbitol: CHEBI:17924; sucrose: CHEBI:17992,,,,,gene deletion: full; gene complementation,,,YVS,34072395,PubMed,10.3390/jof7060431,J Fungi (Basel). 2021 May 29;7(6):431,yanglong@mail.hzau.edu.cn,"The ΔBcgb1 mutants showed reduced mycelial growth rate, but increased aerial hyphae and mycelial biomass, lack of conidiation, failed to form sclerotia, increased resistance to cell wall and oxidative stresses, delayed formation of infection cushions, and decreased virulence.",J Tang 2021,2021,1 gene,Tang-2021-Botrytis cinerea G Protein ß Subunit,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18776,PHI:11616,UniProt,no data found,GenBank,,,,,UvPmk1,,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,spikelet; panicle,MAP kinase,,,MAPK pathway,loss of pathogenicity,,,,,,,,,,no,NaCl; sorbitol; calcofluor white; Congo red; SDS; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34348597,PubMed,10.1080/21505594.2021.1936768,Virulence. 2021 Dec;12(1):1563-1579,luzheng@mail.hzau.edu.cn,"Deletion of UvCGBP1 affected transcriptional and translational levels of UvPmk1 and UvSlt2, both of which were important in virulence.",X Cheng 2021,2021,3 genes,Chen-2021-A novel transcription factor UvCGBP1,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18777,PHI:11617,UniProt,no data found,GenBank,,,,,UvSlt2,,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,spikelet; panicle,MAP kinase,,,MAPK pathway,loss of pathogenicity,,,,,,,,,,no,NaCl; sorbitol; calcofluor white; Congo red; SDS; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34348597,PubMed,10.1080/21505594.2021.1936768,Virulence. 2021 Dec;12(1):1563-1579,luzheng@mail.hzau.edu.cn,"Deletion of UvCGBP1 affected transcriptional and translational levels of UvPmk1 and UvSlt2, both of which were important in virulence.",X Cheng 2021,2021,3 genes,Chen-2021-A novel transcription factor UvCGBP1,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18778,PHI:11618,UniProt,no data found,GenBank,,,,,UvCGBP1,,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,spikelet; panicle,G-box binding transcription factor,,,MAPK pathway,reduced virulence,,,,yes,,reduced,reduced; aberrant,,,no,NaCl; sorbitol; calcofluor white; Congo red; SDS; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34348597,PubMed,10.1080/21505594.2021.1936768,Virulence. 2021 Dec;12(1):1563-1579,luzheng@mail.hzau.edu.cn,"Deletion of UvCGBP1 affected mycelial growth, morphogenesis, conidiation and various morphogenesis- and pathogenesis-associated stress response.",X Cheng 2021,2021,3 genes,Chen-2021-A novel transcription factor UvCGBP1,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18779,PHI:11619,UniProt,K3W1P7,GenBank,EKJ76270,,,CS3096,FpHsp104 (FPSE_03525),,,,,,,101028,Fusarium pseudograminearum,,WZ2-8A,Fusarium crown rot; Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Aikang 58,,,coleoptile,heat shock protein,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34394037,PubMed,10.3389/fmicb.2021.695535,Front Microbiol. 2021 Jul 28;12:695535,honglianli@sina.com,Deletion mutant of FpHsp104 displayed severe defects in the resistance of heat shock during F. pseudograminearum mycelia and conidia when exposed to extreme heat.,H Xia 2021,2021,1 gene,Xia-2021-Heat Stress Tolerance Gene FpHsp104 A,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18780,PHI:11619,UniProt,K3W1P7,GenBank,EKJ76270,,,CS3096,FpHsp104 (FPSE_03525),,,,,,,101028,Fusarium pseudograminearum,,WZ2-8A,Fusarium crown rot; Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),,,,leaf,heat shock protein,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34394037,PubMed,10.3389/fmicb.2021.695535,Front Microbiol. 2021 Jul 28;12:695535,honglianli@sina.com,Deletion mutant of FpHsp104 displayed severe defects in the resistance of heat shock during F. pseudograminearum mycelia and conidia when exposed to extreme heat.,H Xia 2021,2021,1 gene,Xia-2021-Heat Stress Tolerance Gene FpHsp104 A,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18781,PHI:11620,UniProt,no data found,GenBank,,,,,Xonc3711,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Yuanfengzao,,,leaf,small regulatory noncoding RNA,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34297775,PubMed,10.1371/journal.ppat.1009762,PLoS Pathog. 2021 Jul 23;17(7):e1009762,gyouchen@sjtu.edu.c,Deletion of Xonc3711 resulted in a lower tolerance to oxidative stress due to the repression of flagella associated genes and reduced biofilm formation.,Y Wu 2021,2021,1 gene,Wu-2021-A key antisense sRNA modulates the oxi,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18782,PHI:11620,UniProt,no data found,GenBank,,,,,Xonc3711,,,,,,,347,Xanthomonas oryzae,383407,pv. oryzicola strain BLS256,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Yuanfengzao,,,leaf,small regulatory noncoding RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34297775,PubMed,10.1371/journal.ppat.1009762,PLoS Pathog. 2021 Jul 23;17(7):e1009762,gyouchen@sjtu.edu.c,Deletion of Xonc3711 resulted in a lower tolerance to oxidative stress due to the repression of flagella associated genes and reduced biofilm formation.,Y Wu 2021,2021,1 gene,Wu-2021-A key antisense sRNA modulates the oxi,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18783,PHI:11621,UniProt,J9VWG9,GenBank,AFR98822,,,H99,Vlp1 (CNAG_05395),chromosome 14,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,"vacuolar morphogenesis protein, Vam6-like protein",,,,loss of pathogenicity,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulphate (SDS); NaCl; KCl; sorbitol; NaNO2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulphate (SDS): CHEBI:8984; NaCl: CHEBI:267101; KCl: CHEBI:32588; sorbitol: CHEBI:17924; NaNO2: CHEBI:78870,,,,,gene deletion: full; gene complementation,,,YVS,34072011,PubMed,10.3390/jof7060418,J Fungi (Basel). 2021 May 27;7(6):418,tongbaoliu@swu.edu.cn,"The vlp1Δ mutants showed a proliferation defect inside macrophages and a viability defect in the host complement system, which likely contributed to the virulence attenuation of the vlp1Δ mutants.",C L Fan 2021,2021,1 gene,Fan-2021-The Vacuolar Morphogenesis Protein Va,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18784,PHI:11621,UniProt,J9VWG9,GenBank,AFR98822,,,H99,Vlp1 (CNAG_05395),chromosome 14,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,"vacuolar morphogenesis protein, Vam6-like protein",,,,increased virulence (hypervirulence),,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulphate (SDS); NaCl; KCl; sorbitol; NaNO2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulphate (SDS): CHEBI:8984; NaCl: CHEBI:267101; KCl: CHEBI:32588; sorbitol: CHEBI:17924; NaNO2: CHEBI:78870,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34072011,PubMed,10.3390/jof7060418,J Fungi (Basel). 2021 May 27;7(6):418,tongbaoliu@swu.edu.cn,"The vlp1Δ mutants showed a proliferation defect inside macrophages and a viability defect in the host complement system, which likely contributed to the virulence attenuation of the vlp1Δ mutants.",C L Fan 2021,2021,1 gene,Fan-2021-The Vacuolar Morphogenesis Protein Va,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18785,PHI:11621,UniProt,J9VWG9,GenBank,AFR98822,,,H99,Vlp1 (CNAG_05395),chromosome 14,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,"vacuolar morphogenesis protein, Vam6-like protein",,,,reduced virulence,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulphate (SDS); NaCl; KCl; sorbitol; NaNO2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulphate (SDS): CHEBI:8984; NaCl: CHEBI:267101; KCl: CHEBI:32588; sorbitol: CHEBI:17924; NaNO2: CHEBI:78870,,,,,gene deletion: full; gene complementation,,,YVS,34072011,PubMed,10.3390/jof7060418,J Fungi (Basel). 2021 May 27;7(6):418,tongbaoliu@swu.edu.cn,"The vlp1Δ mutants showed a proliferation defect inside macrophages and a viability defect in the host complement system, which likely contributed to the virulence attenuation of the vlp1Δ mutants.",C L Fan 2021,2021,1 gene,Fan-2021-The Vacuolar Morphogenesis Protein Va,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18786,PHI:11622,UniProt,Q9HX66,GenBank,AE004813_4,,,PAO1,RhlE1 (PA3950),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DEAD-box RNA helicase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34151378,PubMed,10.1093/nar/gkab503,Nucleic Acids Res. 2021 Jul 9;49(12):6925-6940,martina.valentini@unige.ch,"RhlE2 controlled, directly and/or indirectly, the expression of virulence genes and is necessary for P. aeruginosa pathogenicity in vivo.",S Hausmann 2021,2021,2 genes,Hausmann-2021-The DEAD-box RNA helicase RhlE2,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18787,PHI:11623,UniProt,Q9HX66,GenBank,AE004813_4,,,PAO1,RhlE2 (PA0428),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DEAD-box RNA helicase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34151378,PubMed,10.1093/nar/gkab503,Nucleic Acids Res. 2021 Jul 9;49(12):6925-6940,martina.valentini@unige.ch,"RhlE2 controlled, directly and/or indirectly, the expression of virulence genes and is necessary for P. aeruginosa pathogenicity in vivo.",S Hausmann 2021,2021,2 genes,Hausmann-2021-The DEAD-box RNA helicase RhlE2,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18788,PHI:11622,UniProt,Q9HX66,GenBank,AE004813_4,,,PAO1,RhlE1 (PA3950),,,,,,PHI:11623,287,Pseudomonas aeruginosa,208964,PAO1,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DEAD-box RNA helicase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34151378,PubMed,10.1093/nar/gkab503,Nucleic Acids Res. 2021 Jul 9;49(12):6925-6940,martina.valentini@unige.ch,"RhlE2 controlled, directly and/or indirectly, the expression of virulence genes and is necessary for P. aeruginosa pathogenicity in vivo.",S Hausmann 2021,2021,2 genes,Hausmann-2021-The DEAD-box RNA helicase RhlE2,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18789,PHI:11623,UniProt,Q9HX66,GenBank,AE004813_4,,,PAO1,RhlE2 (PA0428),,,,,,PHI:11622,287,Pseudomonas aeruginosa,208964,PAO1,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DEAD-box RNA helicase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34151378,PubMed,10.1093/nar/gkab503,Nucleic Acids Res. 2021 Jul 9;49(12):6925-6940,martina.valentini@unige.ch,"RhlE2 controlled, directly and/or indirectly, the expression of virulence genes and is necessary for P. aeruginosa pathogenicity in vivo.",S Hausmann 2021,2021,2 genes,Hausmann-2021-The DEAD-box RNA helicase RhlE2,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18790,PHI:11624,UniProt,E9EB17,GenBank,EFY86849,,,CQMa 102,MaAreB,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,hemolymph,GATA transcription factor,,,,reduced virulence,,yes,yes,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34198996,PubMed,10.3390/jof7070512,J Fungi (Basel). 2021 Jun 27;7(7):512,jinkai@cqu.edu.cn,"Disruption of MaAreB affected the nitrogen utilization and led to decelerated conidial germination and hyphal growth, decreased conidial yield, and lower tolerances to UV-B irradiation and heat-shock.",C Li 2021,2021,1 gene,"Li-2021-MaAreB, a GATA Transcription Factor, I",BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18791,PHI:11625,,no data found,GenBank,Zt09_chr3_00833,,,,ago1,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Obelisk,,,leaf,argonaute protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34208898,PubMed,10.3390/genes12071011,Genes (Basel). 2021 Jun 30;12(7):1011,estukenbrock@bot.uni-kiel.de,"Ago1 specifically affected the ability of Z. tritici to infect and propagate in planta, at least in some wheat cultivars.",M Habig 2021,2021,2 genes,Habig-2021-Ago1 Affects the Virulence of the F,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18792,PHI:11626,,no data found,GenBank,ZT09_chr9_00498,,,,dcl,,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Obelisk,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34208898,PubMed,10.3390/genes12071011,Genes (Basel). 2021 Jun 30;12(7):1011,estukenbrock@bot.uni-kiel.de,"Ago1 specifically affected the ability of Z. tritici to infect and propagate in planta, at least in some wheat cultivars.",M Habig 2021,2021,2 genes,Habig-2021-Ago1 Affects the Virulence of the F,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18793,PHI:11627,UniProt,A0A0Z8JEV9,GenBank,CYV67178,,,LSS8,mutT,,,,,,,1307,Streptococcus suis,,ZY05719,septicemia; meningitis; arthritis; endocarditis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,NTP pyrophosphohydrolase including oxidative damage repair enzyme,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,34077309,PubMed,10.1080/21505594.2021.1936770,Virulence. 2021 Dec;12(1):1538-1549,vszw@njau.edu.cn,MutT deletion mutant increased microbial clearance in host tissues of the infected mice.,Q Li 2021,2021,1 gene,Li-2021-The biological role of MutT in the pat,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18794,PHI:11627,UniProt,A0A0Z8JEV9,GenBank,CYV67178,,,LSS8,mutT,,,,,,,1307,Streptococcus suis,,ZY05719,septicemia; meningitis; arthritis; endocarditis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,NTP pyrophosphohydrolase including oxidative damage repair enzyme,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,34077309,PubMed,10.1080/21505594.2021.1936770,Virulence. 2021 Dec;12(1):1538-1549,vszw@njau.edu.cn,The deletion of mutT attenuated the virulence of SS2 in zebrafish.,Q Li 2021,2021,1 gene,Li-2021-The biological role of MutT in the pat,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18795,PHI:11627,UniProt,A0A0Z8JEV9,GenBank,CYV67178,,,LSS8,mutT,,,,,,,1307,Streptococcus suis,,ZY05719,septicemia; meningitis; arthritis; endocarditis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,NTP pyrophosphohydrolase including oxidative damage repair enzyme,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,34077309,PubMed,10.1080/21505594.2021.1936770,Virulence. 2021 Dec;12(1):1538-1549,vszw@njau.edu.cn,MutT contributed to adhesion and invasion of SS2 to host cells.,Q Li 2021,2021,1 gene,Li-2021-The biological role of MutT in the pat,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18796,PHI:11627,UniProt,A0A0Z8JEV9,GenBank,CYV67178,,,LSS8,mutT,,,,,,,1307,Streptococcus suis,,ZY05719,septicemia; meningitis; arthritis; endocarditis,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,brain microvascular endothelial cell line,NTP pyrophosphohydrolase including oxidative damage repair enzyme,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,34077309,PubMed,10.1080/21505594.2021.1936770,Virulence. 2021 Dec;12(1):1538-1549,vszw@njau.edu.cn,MutT contributed to adhesion and invasion of SS2 to host cells.,Q Li 2021,2021,1 gene,Li-2021-The biological role of MutT in the pat,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18797,PHI:11628,UniProt,W9KJI6,GenBank,EWZ42879,,,Fo47,FoATG12,,,,,,,5507,Fusarium oxysporum,59765,,vascular wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. Desirée,,,tuber,autophagy-like protein,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,KCl; sorbitol,KCl: CHEBI:32588; sorbitol: CHEBI:17924,,,,,gene deletion: full,,,YVS,34066497,PubMed,10.3390/ijms22094932,Int J Mol Sci. 2021 May 6;22(9):4932,arkhalid@cqu.edu.cn,The deletion mutant ΔFoATG12 showed reduction in conidial formation and exhibited impaired aerial hyphae.,A R Khalid 2021,2021,1 gene,Khalid-2021-Functional Analysis of Autophagy-R,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18798,PHI:11628,UniProt,W9KJI6,GenBank,EWZ42879,,,Fo47,FoATG12,,,,,,,5507,Fusarium oxysporum,59765,,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. 4081,Solanum lycopersicum (related: Tomato),,leaf,autophagy-like protein,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,KCl; sorbitol,KCl: CHEBI:32588; sorbitol: CHEBI:17924,,,,,gene deletion: full,,,YVS,34066497,PubMed,10.3390/ijms22094932,Int J Mol Sci. 2021 May 6;22(9):4932,arkhalid@cqu.edu.cn,The deletion mutant ΔFoATG12 showed reduction in conidial formation and exhibited impaired aerial hyphae.,A R Khalid 2021,2021,1 gene,Khalid-2021-Functional Analysis of Autophagy-R,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18799,PHI:11629,UniProt,G4MZ62,GenBank,EHA55335,,,70-15,MoeIF4E3 (MGG_08170),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: Rice),cv. CO-39,,,leaf,translation initiation factor,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced; aberrant,,no,calcofluor white (CFW); sodium dodecyl sulfate (SDS); Congo red (CR); NaCl; DTT,calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red (CR): CHEBI:34653; NaCl: CHEBI:267101; DTT: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,34220879,PubMed,10.3389/fpls.2021.646343,Front Plant Sci. 2021 Jun 16;12:646343,wangzh@fafu.edu.cn,"Disruption of MoeIF4E3 partially impaired conidia germination, appressorium integrity and attenuated the pathogenicity of ΔMoeif4e3 strains.",W Batool 2021,2021,1 gene,Batool-2021-Translation Initiation Factor eIF4,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18800,PHI:11629,UniProt,G4MZ62,GenBank,EHA55335,,,70-15,MoeIF4E3 (MGG_08170),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: Barley),,,,leaf,translation initiation factor,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced; aberrant,,no,calcofluor white (CFW); sodium dodecyl sulfate (SDS); Congo red (CR); NaCl; DTT,calcofluor white (CFW): CHEBI:50011; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red (CR): CHEBI:34653; NaCl: CHEBI:267101; DTT: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,34220879,PubMed,10.3389/fpls.2021.646343,Front Plant Sci. 2021 Jun 16;12:646343,wangzh@fafu.edu.cn,"Disruption of MoeIF4E3 partially impaired conidia germination, appressorium integrity and attenuated the pathogenicity of ΔMoeif4e3 strains.",W Batool 2021,2021,1 gene,Batool-2021-Translation Initiation Factor eIF4,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18801,PHI:11630,UniProt,G2WYE8,GenBank,EGY21106,,,VdLs.17,VdSOD1 (VDAG_02630),chromosome 3,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,seedling,Cu/Zn superoxide dismutase,,,,reduced virulence,,,,,,wild type,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34245085,PubMed,10.1111/mpp.13099,Mol Plant Pathol. 2021 Sep;22(9):1092-1108,kvsubbarao@ucdavis.edu,The absence of a functioning VdSOD1 significantly reduced symptom severity and pathogen colonization in both cotton and Nicotiana benthamiana.,L Tian 2021,2021,1 gene,Tian-2021-Cu_Zn superoxide dismutase (VdSOD1),BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18802,PHI:11630,UniProt,G2WYE8,GenBank,EGY21106,,,VdLs.17,VdSOD1 (VDAG_02630),chromosome 3,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,seedling,Cu/Zn superoxide dismutase,,,,reduced virulence,,,,,,wild type,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34245085,PubMed,10.1111/mpp.13099,Mol Plant Pathol. 2021 Sep;22(9):1092-1108,kvsubbarao@ucdavis.edu,The absence of a functioning VdSOD1 significantly reduced symptom severity and pathogen colonization in both cotton and Nicotiana benthamiana.,L Tian 2021,2021,1 gene,Tian-2021-Cu_Zn superoxide dismutase (VdSOD1),BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18803,PHI:11631,UniProt,L7N648,GenBank,CCP43065,,,H37Rv,PE6 (Rv0335c),,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,non-pathogenic,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,PE family protein; TLR4 agonist,,,,increased virulence (hypervirulence),,,,,,,,,,no,rapamycin; bafilomycin A1,rapamycin: CHEBI:9168; bafilomycin A1: CHEBI:22689,,,,,other evidence: heterologous expression,recombinant Mycobacterium smegmatis producing PE6 from M.tuberculosis was used,,YVS,34322125,PubMed,10.3389/fimmu.2021.696491,Front Immunol. 2021 Jul 12;12:696491,nzehtesham@gmail.com,"Recombinant Mycobacterium smegmatis (M. smegmatis) containing pe6 displayed robust growth in Iron chelated media compared to vector alone transformed cells, which suggests a role of PE6 in iron acquisition.",N Sharma 2021,2021,1 gene,Sharma-2021-Mycobacterium tuberculosis Protein,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18804,PHI:11632,UniProt,A0A095RDM0,GenBank,AIV78373,,,TSV202,regA,chromosome 1,,,,,,28450,Burkholderia pseudomallei,,E8,melioidosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"bacterial regulatory, Fis family protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34048488,PubMed,10.1371/journal.ppat.1009604,PLoS Pathog. 2021 May 28;17(5):e1009604,christian.kohler@med.uni-greifswald.de,"RegAB was not only essential for anaerobic growth, but also for full virulence in cell lines and a mouse infection model.",J PhennI 2021,2021,2 genes,Phenn-2021-RegAB Homolog of Burkholderia pseud,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18805,PHI:11633,UniProt,A0A069AWT6,GenBank,AIV78648,,,TSV202,regB,chromosome 1,,,,,,28450,Burkholderia pseudomallei,,E8,melioidosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,his kinase A domain protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34048488,PubMed,10.1371/journal.ppat.1009604,PLoS Pathog. 2021 May 28;17(5):e1009604,christian.kohler@med.uni-greifswald.de,"RegAB was not only essential for anaerobic growth, but also for full virulence in cell lines and a mouse infection model.",J PhennI 2021,2021,2 genes,Phenn-2021-RegAB Homolog of Burkholderia pseud,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18806,PHI:11632,UniProt,A0A095RDM0,GenBank,AIV78373,,,TSV202,regA,chromosome 1,,,,,,28450,Burkholderia pseudomallei,,E8,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung,"bacterial regulatory, Fis family protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34048488,PubMed,10.1371/journal.ppat.1009604,PLoS Pathog. 2021 May 28;17(5):e1009604,christian.kohler@med.uni-greifswald.de,"RegAB was not only essential for anaerobic growth, but also for full virulence in cell lines and a mouse infection model.",J PhennI 2021,2021,2 genes,Phenn-2021-RegAB Homolog of Burkholderia pseud,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18807,PHI:11633,UniProt,A0A069AWT6,GenBank,AIV78648,,,TSV202,regB,chromosome 1,,,,,,28450,Burkholderia pseudomallei,,E8,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; lung,his kinase A domain protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34048488,PubMed,10.1371/journal.ppat.1009604,PLoS Pathog. 2021 May 28;17(5):e1009604,christian.kohler@med.uni-greifswald.de,"RegAB was not only essential for anaerobic growth, but also for full virulence in cell lines and a mouse infection model.",J PhennI 2021,2021,2 genes,Phenn-2021-RegAB Homolog of Burkholderia pseud,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18808,PHI:11632,UniProt,A0A095RDM0,GenBank,AIV78373,,,TSV202,regA,chromosome 1,,,,,,28450,Burkholderia pseudomallei,,E8,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,"bacterial regulatory, Fis family protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34048488,PubMed,10.1371/journal.ppat.1009604,PLoS Pathog. 2021 May 28;17(5):e1009604,christian.kohler@med.uni-greifswald.de,"RegAB was not only essential for anaerobic growth, but also for full virulence in cell lines and a mouse infection model.",J PhennI 2021,2021,2 genes,Phenn-2021-RegAB Homolog of Burkholderia pseud,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18809,PHI:11633,UniProt,A0A069AWT6,GenBank,AIV78648,,,TSV202,regB,chromosome 1,,,,,,28450,Burkholderia pseudomallei,,E8,melioidosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,his kinase A domain protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34048488,PubMed,10.1371/journal.ppat.1009604,PLoS Pathog. 2021 May 28;17(5):e1009604,christian.kohler@med.uni-greifswald.de,"RegAB was not only essential for anaerobic growth, but also for full virulence in cell lines and a mouse infection model.",J PhennI 2021,2021,2 genes,Phenn-2021-RegAB Homolog of Burkholderia pseud,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18810,PHI:11634,UniProt,P9WHZ9,GenBank,CCP45140,,,H37Rv,ppe38,,,,,,,1773,Mycobacterium tuberculosis,83331,CDC1551,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,PPE family protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34276695,PubMed,10.3389/fimmu.2021.702359,Front Immunol. 2021 Jul 2;12:702359,w.bitter@amsterdamumc.nl,A decreased pro-inflammatory response was observed in macrophages infected with PPE38-deficient M. tuberculosis CDC1551 as compared to wild type bacteria.,J Gallant 2021,2021,1 gene,Gallant-2021-PPE38-Secretion-Dependent Protein,BATCH_108A,2021-09-01,MC,,,,,,,,,,,,,
,,Record 18811,PHI:11635,UniProt,A0A384K4K6,GenBank,ATZ57467,,,B05.10,Bcdim2 (Bcin15p00450),BCIN15,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Castlemart,,,leaf; fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18812,PHI:11636,UniProt,A0A384JCP3,GenBank,ATZ48221,,,B05.10,Bcrid1 (Bcin03p04600),BCIN03,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Castlemart,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18813,PHI:11637,UniProt,A0A384JT02,GenBank,ATZ53718,,,B05.10,Bcrid2 (Bcin09p05050),BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Castlemart,,,leaf; fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18814,PHI:11638,UniProt,A0A384JS52,GenBank,ATZ53321,,,B05.10,Bcdnmt1 (Bcin09p01910),BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Castlemart,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18815,PHI:11635,UniProt,A0A384K4K6,GenBank,ATZ57467,,,B05.10,Bcdim2 (Bcin15p00450),BCIN15,,,,,PHI:11637,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Castlemart,,,leaf; fruit,DNA methyltransferase,,,,loss of pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18816,PHI:11637,UniProt,A0A384JT02,GenBank,ATZ53718,,,B05.10,Bcrid2 (Bcin09p05050),BCIN09,,,,,PHI:11635,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Castlemart,,,leaf; fruit,DNA methyltransferase,,,,loss of pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18817,PHI:11635,UniProt,A0A384K4K6,GenBank,ATZ57467,,,B05.10,Bcdim2 (Bcin15p00450),BCIN15,,,,,PHI:11636,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Castlemart,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18818,PHI:11636,UniProt,A0A384JCP3,GenBank,ATZ48221,,,B05.10,Bcrid1 (Bcin03p04600),BCIN03,,,,,PHI:11635,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Castlemart,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18819,PHI:11636,UniProt,A0A384JCP3,GenBank,ATZ48221,,,B05.10,Bcrid1 (Bcin03p04600),BCIN03,,,,,PHI:11637,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Castlemart,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18820,PHI:11637,UniProt,A0A384JT02,GenBank,ATZ53718,,,B05.10,Bcrid2 (Bcin09p05050),BCIN09,,,,,PHI:11636,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Castlemart,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18821,PHI:11635,UniProt,A0A384K4K6,GenBank,ATZ57467,,,B05.10,Bcdim2 (Bcin15p00450),BCIN15,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: Paradise apple),cv. Fuji,,,fruit,DNA methyltransferase,,,,reduced virulence,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18822,PHI:11636,UniProt,A0A384JCP3,GenBank,ATZ48221,,,B05.10,Bcrid1 (Bcin03p04600),BCIN03,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: Paradise apple),cv. Fuji,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18823,PHI:11637,UniProt,A0A384JT02,GenBank,ATZ53718,,,B05.10,Bcrid2 (Bcin09p05050),BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: Paradise apple),cv. Fuji,,,fruit,DNA methyltransferase,,,,reduced virulence,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18824,PHI:11638,UniProt,A0A384JS52,GenBank,ATZ53321,,,B05.10,Bcdnmt1 (Bcin09p01910),BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: Paradise apple),cv. Fuji,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18825,PHI:11635,UniProt,A0A384K4K6,GenBank,ATZ57467,,,B05.10,Bcdim2 (Bcin15p00450),BCIN15,,,,,PHI:11637,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: Paradise apple),cv. Fuji,,,fruit,DNA methyltransferase,,,,loss of pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18826,PHI:11637,UniProt,A0A384JT02,GenBank,ATZ53718,,,B05.10,Bcrid2 (Bcin09p05050),BCIN09,,,,,PHI:11635,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: Paradise apple),cv. Fuji,,,fruit,DNA methyltransferase,,,,loss of pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18827,PHI:11635,UniProt,A0A384K4K6,GenBank,ATZ57467,,,B05.10,Bcdim2 (Bcin15p00450),BCIN15,,,,,PHI:11636,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: Paradise apple),cv. Fuji,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18828,PHI:11636,UniProt,A0A384JCP3,GenBank,ATZ48221,,,B05.10,Bcrid1 (Bcin03p04600),BCIN03,,,,,PHI:11635,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: Paradise apple),cv. Fuji,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18829,PHI:11636,UniProt,A0A384JCP3,GenBank,ATZ48221,,,B05.10,Bcrid1 (Bcin03p04600),BCIN03,,,,,PHI:11637,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: Paradise apple),cv. Fuji,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18830,PHI:11637,UniProt,A0A384JT02,GenBank,ATZ53718,,,B05.10,Bcrid2 (Bcin09p05050),BCIN09,,,,,PHI:11636,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: Paradise apple),cv. Fuji,,,fruit,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18831,PHI:11635,UniProt,A0A384K4K6,GenBank,ATZ57467,,,B05.10,Bcdim2 (Bcin15p00450),BCIN15,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18832,PHI:11637,UniProt,A0A384JT02,GenBank,ATZ53718,,,B05.10,Bcrid2 (Bcin09p05050),BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,DNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18833,PHI:11635,UniProt,A0A384K4K6,GenBank,ATZ57467,,,B05.10,Bcdim2 (Bcin15p00450),BCIN15,,,,,PHI:11637,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,DNA methyltransferase,,,,loss of pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18834,PHI:11637,UniProt,A0A384JT02,GenBank,ATZ53718,,,B05.10,Bcrid2 (Bcin09p05050),BCIN09,,,,,PHI:11635,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,DNA methyltransferase,,,,loss of pathogenicity,,,,,,,,,,no,5-azacytidine,5-azacytidine: CHEBI:2038,,,,,gene deletion: full,,,YVS,34436198,PubMed,10.3390/jof7080659,J Fungi (Basel). 2021 Aug 14;7(8):659,tsp@ibcas.ac.cn,"The double knockout mutant ΔBcdim2rid2 showed slower mycelial growth, lower spore germination, attenuated oxidative tolerance, and complete pathogenicity loss on various hosts.",Z Zhang 2021,2021,4 genes,Zhang-2021-DNA Methyltransferases Regulate Pat,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18835,PHI:11639,UniProt,A0A1D8PGY4,GenBank,AOW27406,,,SC5314,ste11,chromosome 2,STE11 ΔN467,,,,,5476,Candida albicans,237561,SC5314,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,spleen; liver; kidney; brain,mitogen-activated protein kinase kinase kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34432857,PubMed,10.1371/journal.ppat.1009839,PLoS Pathog. 2021 Aug 25;17(8):e1009839,treynol6@utk.edu,Deletion of CPH1 in a hyperactive STE11ΔN467 background blocked macrophage immune activation and restored virulence during systemic infection in mice.,A S Wagner 2021,2021,2 genes,"Wagner-2021-Activation of Cph1 causes ß(1,3)-g",BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18836,PHI:11639,UniProt,A0A1D8PGY4,GenBank,AOW27406,,,SC5314,ste11,chromosome 2,STE11 ΔN467,,,,PHI:11640,5476,Candida albicans,237561,SC5314,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,mitogen-activated protein kinase kinase kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34432857,PubMed,10.1371/journal.ppat.1009839,PLoS Pathog. 2021 Aug 25;17(8):e1009839,treynol6@utk.edu,Deletion of CPH1 in a hyperactive STE11ΔN467 background blocked macrophage immune activation and restored virulence during systemic infection in mice.,A S Wagner 2021,2021,2 genes,"Wagner-2021-Activation of Cph1 causes ß(1,3)-g",BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18837,PHI:11640,UniProt,P43079,GenBank,AOW26385,,,SC5314,cph1,chromosome 1,,,,,PHI:11639,5476,Candida albicans,237561,SC5314,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34432857,PubMed,10.1371/journal.ppat.1009839,PLoS Pathog. 2021 Aug 25;17(8):e1009839,treynol6@utk.edu,Deletion of CPH1 in a hyperactive STE11ΔN467 background blocked macrophage immune activation and restored virulence during systemic infection in mice.,A S Wagner 2021,2021,2 genes,"Wagner-2021-Activation of Cph1 causes ß(1,3)-g",BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18838,PHI:11639,UniProt,A0A1D8PGY4,GenBank,AOW27406,,,SC5314,ste11,chromosome 2,STE11 ΔN467,,,,PHI:11640,5476,Candida albicans,237561,SC5314,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mitogen-activated protein kinase kinase kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34432857,PubMed,10.1371/journal.ppat.1009839,PLoS Pathog. 2021 Aug 25;17(8):e1009839,treynol6@utk.edu,Deletion of CPH1 in a hyperactive STE11ΔN467 background blocked macrophage immune activation and restored virulence during systemic infection in mice.,A S Wagner 2021,2021,2 genes,"Wagner-2021-Activation of Cph1 causes ß(1,3)-g",BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18839,PHI:11640,UniProt,P43079,GenBank,AOW26385,,,SC5314,cph1,chromosome 1,,,,,PHI:11639,5476,Candida albicans,237561,SC5314,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34432857,PubMed,10.1371/journal.ppat.1009839,PLoS Pathog. 2021 Aug 25;17(8):e1009839,treynol6@utk.edu,Deletion of CPH1 in a hyperactive STE11ΔN467 background blocked macrophage immune activation and restored virulence during systemic infection in mice.,A S Wagner 2021,2021,2 genes,"Wagner-2021-Activation of Cph1 causes ß(1,3)-g",BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18840,PHI:11641,UniProt,A0A059ZQI8,GenBank,AKA32956,,,AB5075-UW,gigA,,,,,,PHI:11642,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,noncanonical two-component system (TCS) response regulator (RR) harboring a protein phosphatase domain,,,,reduced virulence,,,,,,,,reduced,,no,HCl; ZnCl2,HCl: CHEBI:17883; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,34421881,PubMed,10.3389/fmicb.2021.723949,Front Microbiol. 2021 Aug 4;12:723949,zhouhua1@zju.edu.cn,Deletion of gigA/gigB in the ATCC 17978 conferred growth and replication defects within murine macrophages and an inability to kill G. mellonella larvae. The loss of ptsP restored the phenotypes of the gigA/gigB mutant to that of the wild-type.,H Zhou 2021,2021,3 genes,Zhou-2021-The gigA_gigB Genes Regulate the Gro,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18841,PHI:11642,UniProt,A0A0D5YL42,GenBank,AKA32957,,,AB5075-UW,gigB,,,,,,PHI:11641,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,anti-sigma factor antagonist,,,,reduced virulence,,,,,,,,reduced,,no,HCl; ZnCl2,HCl: CHEBI:17883; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,34421881,PubMed,10.3389/fmicb.2021.723949,Front Microbiol. 2021 Aug 4;12:723949,zhouhua1@zju.edu.cn,Deletion of gigA/gigB in the ATCC 17978 conferred growth and replication defects within murine macrophages and an inability to kill G. mellonella larvae. The loss of ptsP restored the phenotypes of the gigA/gigB mutant to that of the wild-type.,H Zhou 2021,2021,3 genes,Zhou-2021-The gigA_gigB Genes Regulate the Gro,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18842,PHI:11643,,no data found,GenBank,SSR03459,,,4300STDY7045752,pstP,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,serine/threonine protein phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,HCl; ZnCl2,HCl: CHEBI:17883; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,34421881,PubMed,10.3389/fmicb.2021.723949,Front Microbiol. 2021 Aug 4;12:723949,zhouhua1@zju.edu.cn,Deletion of gigA/gigB in the ATCC 17978 conferred growth and replication defects within murine macrophages and an inability to kill G. mellonella larvae. The loss of ptsP restored the phenotypes of the gigA/gigB mutant to that of the wild-type.,H Zhou 2021,2021,3 genes,Zhou-2021-The gigA_gigB Genes Regulate the Gro,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18843,PHI:11641,UniProt,A0A059ZQI8,GenBank,AKA32956,,,AB5075-UW,gigA,,,,,,PHI:11642; PHI:11643,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,noncanonical two-component system (TCS) response regulator (RR) harboring a protein phosphatase domain,,,,unaffected pathogenicity,,,,,,,,,,no,HCl; ZnCl2,HCl: CHEBI:17883; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,34421881,PubMed,10.3389/fmicb.2021.723949,Front Microbiol. 2021 Aug 4;12:723949,zhouhua1@zju.edu.cn,Deletion of gigA/gigB in the ATCC 17978 conferred growth and replication defects within murine macrophages and an inability to kill G. mellonella larvae. The loss of ptsP restored the phenotypes of the gigA/gigB mutant to that of the wild-type.,H Zhou 2021,2021,3 genes,Zhou-2021-The gigA_gigB Genes Regulate the Gro,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18844,PHI:11642,UniProt,A0A0D5YL42,GenBank,AKA32957,,,AB5075-UW,gigB,,,,,,PHI:11641; PHI:11643,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,anti-sigma factor antagonist,,,,unaffected pathogenicity,,,,,,,,,,no,HCl; ZnCl2,HCl: CHEBI:17883; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,34421881,PubMed,10.3389/fmicb.2021.723949,Front Microbiol. 2021 Aug 4;12:723949,zhouhua1@zju.edu.cn,Deletion of gigA/gigB in the ATCC 17978 conferred growth and replication defects within murine macrophages and an inability to kill G. mellonella larvae. The loss of ptsP restored the phenotypes of the gigA/gigB mutant to that of the wild-type.,H Zhou 2021,2021,3 genes,Zhou-2021-The gigA_gigB Genes Regulate the Gro,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18845,PHI:11643,,no data found,GenBank,SSR03459,,,4300STDY7045752,pstP,,,,,,PHI:11641; PHI:11642,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,serine/threonine protein phosphatase,,,,unaffected pathogenicity,,,,,,,,,,no,HCl; ZnCl2,HCl: CHEBI:17883; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,34421881,PubMed,10.3389/fmicb.2021.723949,Front Microbiol. 2021 Aug 4;12:723949,zhouhua1@zju.edu.cn,Deletion of gigA/gigB in the ATCC 17978 conferred growth and replication defects within murine macrophages and an inability to kill G. mellonella larvae. The loss of ptsP restored the phenotypes of the gigA/gigB mutant to that of the wild-type.,H Zhou 2021,2021,3 genes,Zhou-2021-The gigA_gigB Genes Regulate the Gro,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18846,PHI:11641,UniProt,A0A059ZQI8,GenBank,AKA32956,,,AB5075-UW,gigA,,,,,,PHI:11642,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,noncanonical two-component system (TCS) response regulator (RR) harboring a protein phosphatase domain,,,,reduced virulence,,,,,,,,reduced,,no,HCl; ZnCl2,HCl: CHEBI:17883; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,34421881,PubMed,10.3389/fmicb.2021.723949,Front Microbiol. 2021 Aug 4;12:723949,zhouhua1@zju.edu.cn,Deletion of gigA/gigB in the ATCC 17978 conferred growth and replication defects within murine macrophages and an inability to kill G. mellonella larvae. The loss of ptsP restored the phenotypes of the gigA/gigB mutant to that of the wild-type.,H Zhou 2021,2021,3 genes,Zhou-2021-The gigA_gigB Genes Regulate the Gro,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18847,PHI:11642,UniProt,A0A0D5YL42,GenBank,AKA32957,,,AB5075-UW,gigB,,,,,,PHI:11641,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,anti-sigma factor antagonist,,,,reduced virulence,,,,,,,,reduced,,no,HCl; ZnCl2,HCl: CHEBI:17883; ZnCl2: CHEBI:49976,,,,,gene deletion: full; gene complementation,,,YVS,34421881,PubMed,10.3389/fmicb.2021.723949,Front Microbiol. 2021 Aug 4;12:723949,zhouhua1@zju.edu.cn,Deletion of gigA/gigB in the ATCC 17978 conferred growth and replication defects within murine macrophages and an inability to kill G. mellonella larvae. The loss of ptsP restored the phenotypes of the gigA/gigB mutant to that of the wild-type.,H Zhou 2021,2021,3 genes,Zhou-2021-The gigA_gigB Genes Regulate the Gro,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18848,PHI:11644,UniProt,T0JVX2,GenBank,EQB44708,,,Cg-14,CgMsb2,,,,,,,474922,Colletotrichum gloeosporioides,,CFCC80308,anthracnose (poplar),eudicots,1217306,Populus x beijingensis (no common name found),,,,leaf,mucin,,,,reduced virulence,,yes,yes,yes,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34414655,PubMed,10.1111/mpp.13126,Mol Plant Pathol. 2021 Aug 19,chengmt@bjfu.edu.cn,"Deletion of CgMsb2 resulted in significant defects in appressorium formation, appressorium penetration, cellophane membrane penetration, and pathogenicity.",X Wang 2021,2021,3 genes,Wang-2021-Mucin Msb2 cooperates with the trans,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18849,PHI:11645,UniProt,T0K4G1,GenBank,EQB46779,,,Cg-14,CgSho1,,,,,,,474922,Colletotrichum gloeosporioides,,CFCC80308,anthracnose (poplar),eudicots,1217306,Populus x beijingensis (no common name found),,,,leaf,transmembrane sensor protein,,,,reduced virulence,,yes,yes,yes,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34414655,PubMed,10.1111/mpp.13126,Mol Plant Pathol. 2021 Aug 19,chengmt@bjfu.edu.cn,"CgSho1 played a minor role and together with CgMsb2 cooperatively regulated host signal recognition, cellophane membrane penetration, and pathogenicity; deletion of CgSho1 resulted in an expansion defect of infection hyphae.",X Wang 2021,2021,3 genes,Wang-2021-Mucin Msb2 cooperates with the trans,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18850,PHI:11646,,no data found,,,,,,CgPth11,,,,,,,474922,Colletotrichum gloeosporioides,,CFCC80308,anthracnose (poplar),eudicots,1217306,Populus x beijingensis (no common name found),,,,leaf,G-protein-coupled receptor,,,,unaffected pathogenicity,,no,no,no,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34414655,PubMed,10.1111/mpp.13126,Mol Plant Pathol. 2021 Aug 19,chengmt@bjfu.edu.cn,"Deletion of CgPth11 in wildtype, ΔCgMsb2, and ΔCgSho1 strains only resulted in a slight defect in appressorium formation at the early stage, and CgPth11 was dispensable for penetration and pathogenicity.",X Wang 2021,2021,3 genes,Wang-2021-Mucin Msb2 cooperates with the trans,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18851,PHI:11647,UniProt,Q8Y5A1,GenBank,CAD00246,,,EGD-e,gloA (lmo2168),,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver,glyoxalase A,,,,reduced virulence,,,,,,,,reduced,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,34407151,PubMed,10.1371/journal.ppat.1009819,PLoS Pathog. 2021 Aug 18;17(8):e1009819,portnoy@berkeley.edu,Deletion of gloB results in attenuated virulence but to a lesser extent than gloA.,A Anaya-Sanchez 2021,2021,2 genes,Anaya-Sanchez-2021-Detoxification of methylgly,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18852,PHI:11648,UniProt,A0A0E0UYV6,GenBank,AEH93273,,,M7,gloB,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver,metallo-beta-lactamase superfamily protein,,,,reduced virulence,,,,,,,,reduced,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,34407151,PubMed,10.1371/journal.ppat.1009819,PLoS Pathog. 2021 Aug 18;17(8):e1009819,portnoy@berkeley.edu,Deletion of gloB results in attenuated virulence but to a lesser extent than gloA.,A Anaya-Sanchez 2021,2021,2 genes,Anaya-Sanchez-2021-Detoxification of methylgly,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18853,PHI:11647,UniProt,Q8Y5A1,GenBank,CAD00246,,,EGD-e,gloA (lmo2168),,,,,,PHI:11648,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver,glyoxalase A,,,,reduced virulence,,,,,,,,reduced,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,34407151,PubMed,10.1371/journal.ppat.1009819,PLoS Pathog. 2021 Aug 18;17(8):e1009819,portnoy@berkeley.edu,Deletion of gloB results in attenuated virulence but to a lesser extent than gloA.,A Anaya-Sanchez 2021,2021,2 genes,Anaya-Sanchez-2021-Detoxification of methylgly,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18854,PHI:11648,UniProt,A0A0E0UYV6,GenBank,AEH93273,,,M7,gloB,,,,,,PHI:11647,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; liver,metallo-beta-lactamase superfamily protein,,,,reduced virulence,,,,,,,,reduced,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,34407151,PubMed,10.1371/journal.ppat.1009819,PLoS Pathog. 2021 Aug 18;17(8):e1009819,portnoy@berkeley.edu,Deletion of gloB results in attenuated virulence but to a lesser extent than gloA.,A Anaya-Sanchez 2021,2021,2 genes,Anaya-Sanchez-2021-Detoxification of methylgly,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18855,PHI:11647,UniProt,Q8Y5A1,GenBank,CAD00246,,,EGD-e,gloA (lmo2168),,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,glyoxalase A,,,,unaffected pathogenicity,,,,,,,,reduced,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,34407151,PubMed,10.1371/journal.ppat.1009819,PLoS Pathog. 2021 Aug 18;17(8):e1009819,portnoy@berkeley.edu,Deletion of gloB results in attenuated virulence but to a lesser extent than gloA.,A Anaya-Sanchez 2021,2021,2 genes,Anaya-Sanchez-2021-Detoxification of methylgly,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18856,PHI:11648,UniProt,A0A0E0UYV6,GenBank,AEH93273,,,M7,gloB,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,metallo-beta-lactamase superfamily protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,34407151,PubMed,10.1371/journal.ppat.1009819,PLoS Pathog. 2021 Aug 18;17(8):e1009819,portnoy@berkeley.edu,Deletion of gloB results in attenuated virulence but to a lesser extent than gloA.,A Anaya-Sanchez 2021,2021,2 genes,Anaya-Sanchez-2021-Detoxification of methylgly,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18857,PHI:11647,UniProt,Q8Y5A1,GenBank,CAD00246,,,EGD-e,gloA (lmo2168),,,,,,PHI:11648,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,glyoxalase A,,,,reduced virulence,,,,,,,,reduced,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,34407151,PubMed,10.1371/journal.ppat.1009819,PLoS Pathog. 2021 Aug 18;17(8):e1009819,portnoy@berkeley.edu,Deletion of gloB results in attenuated virulence but to a lesser extent than gloA.,A Anaya-Sanchez 2021,2021,2 genes,Anaya-Sanchez-2021-Detoxification of methylgly,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18858,PHI:11648,UniProt,A0A0E0UYV6,GenBank,AEH93273,,,M7,gloB,,,,,,PHI:11647,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,metallo-beta-lactamase superfamily protein,,,,reduced virulence,,,,,,,,reduced,,no,methylglyoxal,methylglyoxal: CHEBI:17158,,,,,gene deletion: full; gene complementation,,,YVS,34407151,PubMed,10.1371/journal.ppat.1009819,PLoS Pathog. 2021 Aug 18;17(8):e1009819,portnoy@berkeley.edu,Deletion of gloB results in attenuated virulence but to a lesser extent than gloA.,A Anaya-Sanchez 2021,2021,2 genes,Anaya-Sanchez-2021-Detoxification of methylgly,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18859,PHI:11649,UniProt,A0A0H3GEF3,GenBank,AEO07054,,,10403S,rex,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,redox-sensing transcriptional repressor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18860,PHI:11650,UniProt,G2K3G6,GenBank,AAZ53236,,,10403S,inlA,,,,,,PHI:11651,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18861,PHI:11651,UniProt,P0DQD3,GenBank,AAA25290,,,EGD,inlB,,,,,,PHI:11650,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18862,PHI:11649,UniProt,A0A0H3GEF3,GenBank,AEO07054,,,10403S,rex,,,,,,PHI:11650; PHI:11651,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,redox-sensing transcriptional repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18863,PHI:11650,UniProt,G2K3G6,GenBank,AAZ53236,,,10403S,inlA,,,,,,PHI:11649; PHI:11651,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18864,PHI:11651,UniProt,P0DQD3,GenBank,AAA25290,,,EGD,inlB,,,,,,PHI:11649; PHI:11650,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,internalin B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18865,PHI:11649,UniProt,A0A0H3GEF3,GenBank,AEO07054,,,10403S,rex,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Huh-7 cell line,,,hepatocyte,redox-sensing transcriptional repressor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18866,PHI:11650,UniProt,G2K3G6,GenBank,AAZ53236,,,10403S,inlA,,,,,,PHI:11651,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Huh-7 cell line,,,hepatocyte,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18867,PHI:11651,UniProt,P0DQD3,GenBank,AAA25290,,,EGD,inlB,,,,,,PHI:11650,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Huh-7 cell line,,,hepatocyte,internalin B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18868,PHI:11649,UniProt,A0A0H3GEF3,GenBank,AEO07054,,,10403S,rex,,,,,,PHI:11650; PHI:11651,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Huh-7 cell line,,,hepatocyte,redox-sensing transcriptional repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18869,PHI:11650,UniProt,G2K3G6,GenBank,AAZ53236,,,10403S,inlA,,,,,,PHI:11649; PHI:11651,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Huh-7 cell line,,,hepatocyte,internalin A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18870,PHI:11651,UniProt,P0DQD3,GenBank,AAA25290,,,EGD,inlB,,,,,,PHI:11649; PHI:11650,1639,Listeria monocytogenes,393133,10403S,listeriosis,primates,9606,Homo sapiens (related: human),Huh-7 cell line,,,hepatocyte,internalin B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18871,PHI:11649,UniProt,A0A0H3GEF3,GenBank,AEO07054,,,10403S,rex,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),L2 cell line,,,fibroblast,redox-sensing transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18872,PHI:11649,UniProt,A0A0H3GEF3,GenBank,AEO07054,,,10403S,rex,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),TIB73 cell line,,,hepatocyte,redox-sensing transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18873,PHI:11649,UniProt,A0A0H3GEF3,GenBank,AEO07054,,,10403S,rex,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),,,,bone marrow-derived macrophage,redox-sensing transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18874,PHI:11649,UniProt,A0A0H3GEF3,GenBank,AEO07054,,,10403S,rex,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; gall bladder; gastrointestinal tract,redox-sensing transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34398937,PubMed,10.1371/journal.ppat.1009379,PLoS Pathog. 2021 Aug 16;17(8):e1009379,reniere@uw.edu,Strain lacking rex was more resistant to acidified bile and invaded host cells better than wild type.,C R Halsey 2021,2021,3 genes,Halsey-2021-The redox-responsive transcription,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18875,PHI:11652,UniProt,Q884Y7,GenBank,AAO55467,,,DC3000,fliC,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,infection,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34394146,PubMed,10.3389/fpls.2021.692606,Front Plant Sci. 2021 Jul 29;12:692606,ElsJM.VanDamme@ugent.be,Pst DC3000 fliC mutant caused reduced infection symptoms in Arabidopsis thaliana plants. Host gene alteration data available for F-Box Nictaba.,A Romero-Pérez 2021,2021,1 gene,Romero-Pérez-2021-Overexpression of F-Box Nict,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18876,PHI:11653,UniProt,P14756,GenBank,AE004791_8,,,PAO1,lasB,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,elastase or pseudolysin which is a secreted type II Zn2+ metalloendopeptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34393497,PubMed,10.2147/JIR.S322960,J Inflamm Res. 2021 Aug 6;14:3767-3780,panshuming@xinhuamed.com.cn,Purified LasB recapitulated lung injury similar to P. aeruginosa infection in vivo.,Y Zhu 2021,2021,1 gene,Zhu-2021-Clinical Strains of Pseudomonas aerug,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18877,PHI:11653,UniProt,P14756,GenBank,AE004791_8,,,PAO1,lasB,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,opportunistic infection,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,lung,elastase or pseudolysin which is a secreted type II Zn2+ metalloendopeptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34393497,PubMed,10.2147/JIR.S322960,J Inflamm Res. 2021 Aug 6;14:3767-3780,panshuming@xinhuamed.com.cn,Purified LasB recapitulated lung injury similar to P. aeruginosa infection in vivo.,Y Zhu 2021,2021,1 gene,Zhu-2021-Clinical Strains of Pseudomonas aerug,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18878,PHI:11654,UniProt,no data found,GenBank,QZJ85038,,,,VmHbh1,,,,,,,105487,Valsa mali,,LXS080601,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,hydroxybenzoate hydroxylase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34390112,PubMed,10.1111/mpp.13119,Mol Plant Pathol. 2021 Aug 13,cxwang@qau.edu.cn,"Of the four genes, the VmHbh1 and VmHbh4 deletion mutants considerably attenuated V. mali virulence in apple leaves and in twigs, coupled with much reduced toxin levels.",L Meng 2021,2021,4 genes,Meng-2021-Hydroxybenzoate hydroxylase genes un,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18879,PHI:11655,UniProt,no data found,GenBank,QZJ85036,,,,VmHbh2,,,,,,,105487,Valsa mali,,LXS080601,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,hydroxybenzoate hydroxylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34390112,PubMed,10.1111/mpp.13119,Mol Plant Pathol. 2021 Aug 13,cxwang@qau.edu.cn,"Of the four genes, the VmHbh1 and VmHbh4 deletion mutants considerably attenuated V. mali virulence in apple leaves and in twigs, coupled with much reduced toxin levels.",L Meng 2021,2021,4 genes,Meng-2021-Hydroxybenzoate hydroxylase genes un,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18880,PHI:11656,UniProt,no data found,GenBank,QZJ85037,,,,VmHbh3,,,,,,,105487,Valsa mali,,LXS080601,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,hydroxybenzoate hydroxylase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34390112,PubMed,10.1111/mpp.13119,Mol Plant Pathol. 2021 Aug 13,cxwang@qau.edu.cn,"Of the four genes, the VmHbh1 and VmHbh4 deletion mutants considerably attenuated V. mali virulence in apple leaves and in twigs, coupled with much reduced toxin levels.",L Meng 2021,2021,4 genes,Meng-2021-Hydroxybenzoate hydroxylase genes un,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18881,PHI:11657,UniProt,no data found,GenBank,QZJ85035,,,,VmHbh4,,,,,,,105487,Valsa mali,,LXS080601,Valsa canker,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,hydroxybenzoate hydroxylase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34390112,PubMed,10.1111/mpp.13119,Mol Plant Pathol. 2021 Aug 13,cxwang@qau.edu.cn,"Of the four genes, the VmHbh1 and VmHbh4 deletion mutants considerably attenuated V. mali virulence in apple leaves and in twigs, coupled with much reduced toxin levels.",L Meng 2021,2021,4 genes,Meng-2021-Hydroxybenzoate hydroxylase genes un,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18882,PHI:11658,UniProt,Q57DN5,GenBank,AAX74249,,,9-941,exoR,chromosome I,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,two-component regulatory system (TCS) and a global inhibitor,,,,unaffected pathogenicity,,,,,,,,,,no,polymyxin B,polymyxin B: CHEBI:8309,,,,,gene deletion: full,,,YVS,34388167,PubMed,10.1371/journal.pone.0254568,PLoS One. 2021 Aug 13;16(8):e0254568,catguz@una.cr,"The exoR mutant strain showed no significant differences as compared to the wild-type strain, related to resistance to polymyxin B or human non-immune serum, intracellular replication, or infectivity in a mice model.",A Castillo-Zeledón 2021,2021,1 gene,Castillo-Zeledó-2021-A Sinorhizobium meliloti,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18883,PHI:11658,UniProt,Q57DN5,GenBank,AAX74249,,,9-941,exoR,chromosome I,,,,,,235,Brucella abortus,359391,2308,brucellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,two-component regulatory system (TCS) and a global inhibitor,,,,unaffected pathogenicity,,,,,,,,,,no,polymyxin B,polymyxin B: CHEBI:8309,,,,,gene deletion: full,,,YVS,34388167,PubMed,10.1371/journal.pone.0254568,PLoS One. 2021 Aug 13;16(8):e0254568,catguz@una.cr,"The exoR mutant strain showed no significant differences as compared to the wild-type strain, related to resistance to polymyxin B or human non-immune serum, intracellular replication, or infectivity in a mice model.",A Castillo-Zeledón 2021,2021,1 gene,Castillo-Zeledó-2021-A Sinorhizobium meliloti,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18884,PHI:11658,UniProt,Q57DN5,GenBank,AAX74249,,,9-941,exoR,chromosome I,,,,,,235,Brucella abortus,359391,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,two-component regulatory system (TCS) and a global inhibitor,,,,unaffected pathogenicity,,,,,,,,,,no,polymyxin B,polymyxin B: CHEBI:8309,,,,,gene deletion: full,,,YVS,34388167,PubMed,10.1371/journal.pone.0254568,PLoS One. 2021 Aug 13;16(8):e0254568,catguz@una.cr,"The exoR mutant strain showed no significant differences as compared to the wild-type strain, related to resistance to polymyxin B or human non-immune serum, intracellular replication, or infectivity in a mice model.",A Castillo-Zeledón 2021,2021,1 gene,Castillo-Zeledó-2021-A Sinorhizobium meliloti,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18885,PHI:11659,UniProt,A0A0F7V0G2,GenBank,,,,,MCA1,,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,metacaspase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34384491,PubMed,10.1186/s13071-021-04878-0,Parasit Vectors. 2021 Aug 12;14(1):400,qunliu@cau.edu.cn,The double-knockout strain had slower proliferation and was able to develop bradyzoites both in vitro and in vivo.,M Li 2021,2021,2 genes,Li-2021-Requirement of Toxoplasma gondii metac,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18886,PHI:11660,UniProt,no data found,GenBank,,,,,MCA2,,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,metacaspase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34384491,PubMed,10.1186/s13071-021-04878-0,Parasit Vectors. 2021 Aug 12;14(1):400,qunliu@cau.edu.cn,The double-knockout strain had slower proliferation and was able to develop bradyzoites both in vitro and in vivo.,M Li 2021,2021,2 genes,Li-2021-Requirement of Toxoplasma gondii metac,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18887,PHI:11659,UniProt,A0A0F7V0G2,GenBank,,,,,MCA1,,,,,,PHI:11660,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,metacaspase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34384491,PubMed,10.1186/s13071-021-04878-0,Parasit Vectors. 2021 Aug 12;14(1):400,qunliu@cau.edu.cn,The double-knockout strain had slower proliferation and was able to develop bradyzoites both in vitro and in vivo.,M Li 2021,2021,2 genes,Li-2021-Requirement of Toxoplasma gondii metac,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18888,PHI:11660,UniProt,no data found,GenBank,,,,,MCA2,,,,,,PHI:11659,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,metacaspase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34384491,PubMed,10.1186/s13071-021-04878-0,Parasit Vectors. 2021 Aug 12;14(1):400,qunliu@cau.edu.cn,The double-knockout strain had slower proliferation and was able to develop bradyzoites both in vitro and in vivo.,M Li 2021,2021,2 genes,Li-2021-Requirement of Toxoplasma gondii metac,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18889,PHI:11659,UniProt,A0A0F7V0G2,GenBank,,,,,MCA1,,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,metacaspase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34384491,PubMed,10.1186/s13071-021-04878-0,Parasit Vectors. 2021 Aug 12;14(1):400,qunliu@cau.edu.cn,The double-knockout strain had slower proliferation and was able to develop bradyzoites both in vitro and in vivo.,M Li 2021,2021,2 genes,Li-2021-Requirement of Toxoplasma gondii metac,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18890,PHI:11660,UniProt,no data found,GenBank,,,,,MCA2,,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,metacaspase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34384491,PubMed,10.1186/s13071-021-04878-0,Parasit Vectors. 2021 Aug 12;14(1):400,qunliu@cau.edu.cn,The double-knockout strain had slower proliferation and was able to develop bradyzoites both in vitro and in vivo.,M Li 2021,2021,2 genes,Li-2021-Requirement of Toxoplasma gondii metac,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18891,PHI:11659,UniProt,A0A0F7V0G2,GenBank,,,,,MCA1,,,,,,PHI:11660,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,metacaspase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34384491,PubMed,10.1186/s13071-021-04878-0,Parasit Vectors. 2021 Aug 12;14(1):400,qunliu@cau.edu.cn,The double-knockout strain had slower proliferation and was able to develop bradyzoites both in vitro and in vivo.,M Li 2021,2021,2 genes,Li-2021-Requirement of Toxoplasma gondii metac,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18892,PHI:11660,UniProt,no data found,GenBank,,,,,MCA2,,,,,,PHI:11659,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,metacaspase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34384491,PubMed,10.1186/s13071-021-04878-0,Parasit Vectors. 2021 Aug 12;14(1):400,qunliu@cau.edu.cn,The double-knockout strain had slower proliferation and was able to develop bradyzoites both in vitro and in vivo.,M Li 2021,2021,2 genes,Li-2021-Requirement of Toxoplasma gondii metac,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18893,PHI:11661,UniProt,A0A8E5JS15,GenBank,QVD38856,,,LT263,CBP3,,S24A; S31A,,,,,4784,Phytophthora capsici,763924,LT1534,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: transgenic plants,,,YVS,34382319,PubMed,10.1111/mpp.13116,Mol Plant Pathol. 2021 Aug 11,ddou@cau.edu.cn,Ser24 was required for cell death-inducing activity of PcCBP3.,Z Yin 2021,2021,1 gene,Yin-2021-Phytophthora capsici CBM1-containing,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18894,PHI:11661,UniProt,A0A8E5JS15,GenBank,QVD38856,,,LT263,CBP3,,,,,,,4784,Phytophthora capsici,763924,LT1534,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,34382319,PubMed,10.1111/mpp.13116,Mol Plant Pathol. 2021 Aug 11,ddou@cau.edu.cn,Ser24 was required for cell death-inducing activity of PcCBP3.,Z Yin 2021,2021,1 gene,Yin-2021-Phytophthora capsici CBM1-containing,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18895,PHI:11662,UniProt,no data found,GenBank,ABO11030,,,ATCC 17978,A1S_0579,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34375563,PubMed,10.1080/21505594.2021.1961660,Virulence. 2021 Dec;12(1):2122-2132,shinms@knu.ac.kr,A significant reduction in adherent bacteria was noted in the ppGpp-deficient strain.,K Kim 2021,2021,1 gene,Kim-2021-ppGpp signaling plays a critical role,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18896,PHI:11662,UniProt,no data found,GenBank,ABO11030,,,ATCC 17978,A1S_0579,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34375563,PubMed,10.1080/21505594.2021.1961660,Virulence. 2021 Dec;12(1):2122-2132,shinms@knu.ac.kr,Bacterial number in lung and blood samples was reduced in mice infected with the ppGpp-deficient strain than in the wild-type.,K Kim 2021,2021,1 gene,Kim-2021-ppGpp signaling plays a critical role,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18897,PHI:11663,UniProt,Q8E565,GenBank,CAD46826,,,NEM316,gbs1167,,,,,,,1311,Streptococcus agalactiae,211110,NEM316,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; heart; brain; liver; spleen,redox-sensing transcriptional repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34370789,PubMed,10.1371/journal.ppat.1009791,PLoS Pathog. 2021 Aug 9;17(8):e1009791,philippe.gaudu@inrae.fr,Rex enhanced GBS virulence after disseminated infection in mice.,T Franza 2021,2021,1 gene,Franza-2021-NAD+ pool depletion as a signal fo,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18898,PHI:11663,UniProt,Q8E565,GenBank,CAD46826,,,NEM316,gbs1167,,,,,,,1311,Streptococcus agalactiae,211110,NEM316,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,redox-sensing transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34370789,PubMed,10.1371/journal.ppat.1009791,PLoS Pathog. 2021 Aug 9;17(8):e1009791,philippe.gaudu@inrae.fr,Rex enhanced GBS virulence after disseminated infection in mice.,T Franza 2021,2021,1 gene,Franza-2021-NAD+ pool depletion as a signal fo,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18899,PHI:11663,UniProt,Q8E565,GenBank,CAD46826,,,NEM316,gbs1167,,,,,,,1311,Streptococcus agalactiae,211110,NEM316,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,heart; liver; kidney,redox-sensing transcriptional repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34370789,PubMed,10.1371/journal.ppat.1009791,PLoS Pathog. 2021 Aug 9;17(8):e1009791,philippe.gaudu@inrae.fr,Rex enhanced GBS virulence after disseminated infection in mice.,T Franza 2021,2021,1 gene,Franza-2021-NAD+ pool depletion as a signal fo,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18900,PHI:11664,UniProt,P45004,GenBank,,,,,dmsA,,,,,,,727,Haemophilus influenzae,,Hi2019,Haemophilus influenzae disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; bronchoalveolar lavage fluid,"putative dimethylsulfoxide (DMSO) reductase, catalytic subunit",,,,reduced virulence,,,,,,,,wild type,,no,HOCl,HOCl: CHEBI:24757,,,,,gene deletion: full; gene complementation,,,YVS,34367088,PubMed,10.3389/fmicb.2021.686833,Front Microbiol. 2021 Jul 22;12:686833,u.kappler@uq.edu.au,"In the mouse model of lung infection, Hi20191ΔdmsA was strongly attenuated.",R Dhouib 2021,2021,1 gene,Dhouib-2021-The DmsABC Sulfoxide Reductase Sup,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18901,PHI:11664,UniProt,P45004,GenBank,,,,,dmsA,,,,,,,727,Haemophilus influenzae,,Hi2019,Haemophilus influenzae disease,primates,9606,Homo sapiens (related: human),16HBE14 cell line,,,bronchial epithelial cell line,"putative dimethylsulfoxide (DMSO) reductase, catalytic subunit",,,,reduced virulence,,,,,,,,wild type,,no,HOCl,HOCl: CHEBI:24757,,,,,gene deletion: full; gene complementation,,,YVS,34367088,PubMed,10.3389/fmicb.2021.686833,Front Microbiol. 2021 Jul 22;12:686833,u.kappler@uq.edu.au,"In the mouse model of lung infection, Hi20191ΔdmsA was strongly attenuated.",R Dhouib 2021,2021,1 gene,Dhouib-2021-The DmsABC Sulfoxide Reductase Sup,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18902,PHI:11664,UniProt,P45004,GenBank,,,,,dmsA,,,,,,,727,Haemophilus influenzae,,Hi2019,Haemophilus influenzae disease,primates,9606,Homo sapiens (related: human),,,,neutrophil,"putative dimethylsulfoxide (DMSO) reductase, catalytic subunit",,,,reduced virulence,,,,,,,,wild type,,no,HOCl,HOCl: CHEBI:24757,,,,,gene deletion: full; gene complementation,,,YVS,34367088,PubMed,10.3389/fmicb.2021.686833,Front Microbiol. 2021 Jul 22;12:686833,u.kappler@uq.edu.au,"In the mouse model of lung infection, Hi20191ΔdmsA was strongly attenuated.",R Dhouib 2021,2021,1 gene,Dhouib-2021-The DmsABC Sulfoxide Reductase Sup,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18903,PHI:11665,UniProt,G7ZK59,GenBank,CBX55336,,,5,hrpL,,,,,,,29438,Pseudomonas savastanoi,360920,pv. nerii strain Psn23,knot (olive),eudicots,63479,Nerium oleander (related: common oleander),,,,stem,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34361883,PubMed,10.3390/microorganisms9071447,Microorganisms. 2021 Jul 5;9(7):1447,lgrodriguez@uma.es,HrpL was essential for symptom development in both non-host and host plants.,A Moreno-Pérez 2021,2021,1 gene,Moreno-Pérez-2021-HrpL Regulon of Bacterial Pa,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18904,PHI:11665,UniProt,G7ZK59,GenBank,CBX55336,,,5,hrpL,,,,,,,29438,Pseudomonas savastanoi,360920,pv. fraxini strain NCPPB 1006,knot (olive),eudicots,38873,Fraxinus excelsior (related: European ash),,,,stem,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34361883,PubMed,10.3390/microorganisms9071447,Microorganisms. 2021 Jul 5;9(7):1447,lgrodriguez@uma.es,HrpL was essential for symptom development in both non-host and host plants.,A Moreno-Pérez 2021,2021,1 gene,Moreno-Pérez-2021-HrpL Regulon of Bacterial Pa,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18905,PHI:11665,UniProt,G7ZK59,GenBank,CBX55336,,,5,hrpL,,,,,,,29438,Pseudomonas savastanoi,360920,pv. retacarpa strain CECT 4861,knot (olive),eudicots,49838,Retama sphaerocarpa (no common name found),,,,stem,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34361883,PubMed,10.3390/microorganisms9071447,Microorganisms. 2021 Jul 5;9(7):1447,lgrodriguez@uma.es,HrpL was essential for symptom development in both non-host and host plants.,A Moreno-Pérez 2021,2021,1 gene,Moreno-Pérez-2021-HrpL Regulon of Bacterial Pa,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18906,PHI:11665,UniProt,G7ZK59,GenBank,CBX55336,,,5,hrpL,,,,,,,29438,Pseudomonas savastanoi,360920,pv. mandevillae strain Ph3,knot (olive),eudicots,52837,Mandevilla sanderi (related: Mexican love vine),,,,stem,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34361883,PubMed,10.3390/microorganisms9071447,Microorganisms. 2021 Jul 5;9(7):1447,lgrodriguez@uma.es,HrpL was essential for symptom development in both non-host and host plants.,A Moreno-Pérez 2021,2021,1 gene,Moreno-Pérez-2021-HrpL Regulon of Bacterial Pa,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18907,PHI:11665,UniProt,G7ZK59,GenBank,CBX55336,,,5,hrpL,,,,,,,29438,Pseudomonas savastanoi,360920,pv. savastanoi strain NCPPB 3335,knot (olive),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Newdel,,,leaf,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34361883,PubMed,10.3390/microorganisms9071447,Microorganisms. 2021 Jul 5;9(7):1447,lgrodriguez@uma.es,HrpL was essential for symptom development in both non-host and host plants.,A Moreno-Pérez 2021,2021,1 gene,Moreno-Pérez-2021-HrpL Regulon of Bacterial Pa,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18908,PHI:11665,UniProt,G7ZK59,GenBank,CBX55336,,,5,hrpL,,,,,,,29438,Pseudomonas savastanoi,360920,pv. savastanoi strain NCPPB 3335,knot (olive),eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,leaf,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34361883,PubMed,10.3390/microorganisms9071447,Microorganisms. 2021 Jul 5;9(7):1447,lgrodriguez@uma.es,HrpL was essential for symptom development in both non-host and host plants.,A Moreno-Pérez 2021,2021,1 gene,Moreno-Pérez-2021-HrpL Regulon of Bacterial Pa,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18909,PHI:11666,UniProt,A0A125YP03,GenBank,EPT26880,,,ME49,dsk2a (TGME49_223680),chromosome X,,,,,PHI:11667,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,ubiquitin family protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,34360709,PubMed,10.3390/ijms22157943,Int J Mol Sci. 2021 Jul 26;22(15):7943,qunliu@cau.edu.cn,"Deletion of the DSK2s inhibited the growth of T. gondii in vitro; however, it did not affect virulence in mice.",H Zhang 2021,2021,2 genes,Zhang-2021-Toxoplasma gondii UBL-UBA Shuttle P,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18910,PHI:11667,UniProt,S8GFS1,GenBank,EPT30680,,,ME49,dsk2b (TGME49_240700),chromosome VI,,,,,PHI:11666,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,ubiquitin family protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,34360709,PubMed,10.3390/ijms22157943,Int J Mol Sci. 2021 Jul 26;22(15):7943,qunliu@cau.edu.cn,"Deletion of the DSK2s inhibited the growth of T. gondii in vitro; however, it did not affect virulence in mice.",H Zhang 2021,2021,2 genes,Zhang-2021-Toxoplasma gondii UBL-UBA Shuttle P,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18911,PHI:11668,UniProt,A0A0R6L508,GenBank,AKF16168,,,SHP45,mcr-1,,,,,,,562,Escherichia coli,,SHP45,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,probable phosphatidylethanolamine transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34356793,PubMed,10.3390/antibiotics10070872,Antibiotics (Basel). 2021 Jul 19;10(7):872,sjz@cau.edu.cn,MCR expression increased bacterial virulence in vitro and in vivo.,W Li 2021,2021,5 genes,Li-2021-MCR Expression Conferring Varied Fitne,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18912,PHI:11669,UniProt,A0A1C3NEV1,GenBank,SBV31106,,,KP37,mcr-2,,,,,,,562,Escherichia coli,,SHP45,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative integral membrane protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34356793,PubMed,10.3390/antibiotics10070872,Antibiotics (Basel). 2021 Jul 19;10(7):872,sjz@cau.edu.cn,MCR expression increased bacterial virulence in vitro and in vivo.,W Li 2021,2021,5 genes,Li-2021-MCR Expression Conferring Varied Fitne,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18913,PHI:11670,UniProt,A0A2R2ZJD0,GenBank,AUV50255,,,,mcr-3,,,,,,,562,Escherichia coli,,SHP45,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,phosphoethanolamine--lipid A transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34356793,PubMed,10.3390/antibiotics10070872,Antibiotics (Basel). 2021 Jul 19;10(7):872,sjz@cau.edu.cn,MCR expression increased bacterial virulence in vitro and in vivo.,W Li 2021,2021,5 genes,Li-2021-MCR Expression Conferring Varied Fitne,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18914,PHI:11671,UniProt,A0A2R8G1S3,GenBank,AVP73878,,,11-AB01699,mcr-4,,,,,,,562,Escherichia coli,,SHP45,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,phosphoethanolamine-lipid A transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34356793,PubMed,10.3390/antibiotics10070872,Antibiotics (Basel). 2021 Jul 19;10(7):872,sjz@cau.edu.cn,MCR expression increased bacterial virulence in vitro and in vivo.,W Li 2021,2021,5 genes,Li-2021-MCR Expression Conferring Varied Fitne,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18915,PHI:11672,UniProt,A0A348E6W9,GenBank,AVU81997,,,PEC15-AB00674-RC,mcr-5,,,,,,,562,Escherichia coli,,SHP45,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,phosphoethanolamine transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34356793,PubMed,10.3390/antibiotics10070872,Antibiotics (Basel). 2021 Jul 19;10(7):872,sjz@cau.edu.cn,MCR expression increased bacterial virulence in vitro and in vivo.,W Li 2021,2021,5 genes,Li-2021-MCR Expression Conferring Varied Fitne,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18916,PHI:11668,UniProt,A0A0R6L508,GenBank,AKF16168,,,SHP45,mcr-1,,,,,,,562,Escherichia coli,,SHP45,infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,probable phosphatidylethanolamine transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34356793,PubMed,10.3390/antibiotics10070872,Antibiotics (Basel). 2021 Jul 19;10(7):872,sjz@cau.edu.cn,MCR expression increased bacterial virulence in vitro and in vivo.,W Li 2021,2021,5 genes,Li-2021-MCR Expression Conferring Varied Fitne,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18917,PHI:11669,UniProt,A0A1C3NEV1,GenBank,SBV31106,,,KP37,mcr-2,,,,,,,562,Escherichia coli,,SHP45,infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,putative integral membrane protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34356793,PubMed,10.3390/antibiotics10070872,Antibiotics (Basel). 2021 Jul 19;10(7):872,sjz@cau.edu.cn,MCR expression increased bacterial virulence in vitro and in vivo.,W Li 2021,2021,5 genes,Li-2021-MCR Expression Conferring Varied Fitne,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18918,PHI:11670,UniProt,A0A2R2ZJD0,GenBank,AUV50255,,,,mcr-3,,,,,,,562,Escherichia coli,,SHP45,infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,phosphoethanolamine--lipid A transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34356793,PubMed,10.3390/antibiotics10070872,Antibiotics (Basel). 2021 Jul 19;10(7):872,sjz@cau.edu.cn,MCR expression increased bacterial virulence in vitro and in vivo.,W Li 2021,2021,5 genes,Li-2021-MCR Expression Conferring Varied Fitne,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18919,PHI:11671,UniProt,A0A2R8G1S3,GenBank,AVP73878,,,11-AB01699,mcr-4,,,,,,,562,Escherichia coli,,SHP45,infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,phosphoethanolamine-lipid A transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34356793,PubMed,10.3390/antibiotics10070872,Antibiotics (Basel). 2021 Jul 19;10(7):872,sjz@cau.edu.cn,MCR expression increased bacterial virulence in vitro and in vivo.,W Li 2021,2021,5 genes,Li-2021-MCR Expression Conferring Varied Fitne,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18920,PHI:11672,UniProt,A0A348E6W9,GenBank,AVU81997,,,PEC15-AB00674-RC,mcr-5,,,,,,,562,Escherichia coli,,SHP45,infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,phosphoethanolamine transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34356793,PubMed,10.3390/antibiotics10070872,Antibiotics (Basel). 2021 Jul 19;10(7):872,sjz@cau.edu.cn,MCR expression increased bacterial virulence in vitro and in vivo.,W Li 2021,2021,5 genes,Li-2021-MCR Expression Conferring Varied Fitne,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18921,PHI:11673,UniProt,I1RXF8,GenBank,FGRRES_09025,,,,dcl1,,,,,,PHI:11674,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,double stranded RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34351929,PubMed,10.1371/journal.pone.0252365,PLoS One. 2021 Aug 5;16(8):e0252365,Karl-Heinz.Kogel@agrar.uni-giessen.de,Fusarium graminearum DCL mutants are less virulent on barley and Brachypodium leaves.,B T Werner 2021,2021,2 genes,Werner-2021-Fusarium graminearum DICER-like-de,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18922,PHI:11674,UniProt,I1RKJ8,GenBank,FGRRES_04408,,,,dcl2,,,,,,PHI:11673,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,double stranded RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34351929,PubMed,10.1371/journal.pone.0252365,PLoS One. 2021 Aug 5;16(8):e0252365,Karl-Heinz.Kogel@agrar.uni-giessen.de,Fusarium graminearum DCL mutants are less virulent on barley and Brachypodium leaves.,B T Werner 2021,2021,2 genes,Werner-2021-Fusarium graminearum DICER-like-de,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18923,PHI:11673,UniProt,I1RXF8,GenBank,FGRRES_09025,,,,dcl1,,,,,,PHI:11674,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),Bd21-3 line,,,spikelet,double stranded RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34351929,PubMed,10.1371/journal.pone.0252365,PLoS One. 2021 Aug 5;16(8):e0252365,Karl-Heinz.Kogel@agrar.uni-giessen.de,Fusarium graminearum DCL mutants are less virulent on barley and Brachypodium leaves.,B T Werner 2021,2021,2 genes,Werner-2021-Fusarium graminearum DICER-like-de,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18924,PHI:11674,UniProt,I1RKJ8,GenBank,FGRRES_04408,,,,dcl2,,,,,,PHI:11673,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,15368,Brachypodium distachyon (related: stiff brome),Bd21-3 line,,,spikelet,double stranded RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34351929,PubMed,10.1371/journal.pone.0252365,PLoS One. 2021 Aug 5;16(8):e0252365,Karl-Heinz.Kogel@agrar.uni-giessen.de,Fusarium graminearum DCL mutants are less virulent on barley and Brachypodium leaves.,B T Werner 2021,2021,2 genes,Werner-2021-Fusarium graminearum DICER-like-de,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18925,PHI:11675,UniProt,E9F971,GenBank,EFY95676,,,ARSEF 23,coh1 (MAA_08820),,,,coh2 (MAA_07838),UniProt: E9F6D9; GenBank: EFY96777,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemocoel,regulatory protein,,,,reduced virulence,,no,no,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34347783,PubMed,10.1371/journal.pbio.3001360,PLoS Biol. 2021 Aug 4;19(8):e3001360,wfang1@zju.edu.cn,COH1 was involved in real hemocoel colonization and COH2 was involved in pathogenicity.,X Zhang 2021,2021,2 genes,Zhang-2021-A novel cascade allows Metarhizium,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18926,PHI:11676,UniProt,E9F6D9,GenBank,EFY96777,,,ARSEF 23,coh2 (MAA_07838),,,,coh1 (MAA_08820),UniProt: E9F971; GenBank: EFY95676,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemocoel,bZip transcription factor,,,,reduced virulence,,yes,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34347783,PubMed,10.1371/journal.pbio.3001360,PLoS Biol. 2021 Aug 4;19(8):e3001360,wfang1@zju.edu.cn,COH1 was involved in real hemocoel colonization and COH2 was involved in pathogenicity.,X Zhang 2021,2021,2 genes,Zhang-2021-A novel cascade allows Metarhizium,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18927,PHI:11675,UniProt,E9F971,GenBank,EFY95676,,,ARSEF 23,coh1 (MAA_08820),,,,coh2 (MAA_07838),UniProt: E9F6D9; GenBank: EFY96777,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemocoel,regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34347783,PubMed,10.1371/journal.pbio.3001360,PLoS Biol. 2021 Aug 4;19(8):e3001360,wfang1@zju.edu.cn,COH1 was involved in real hemocoel colonization and COH2 was involved in pathogenicity.,X Zhang 2021,2021,2 genes,Zhang-2021-A novel cascade allows Metarhizium,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18928,PHI:11676,UniProt,E9F6D9,GenBank,EFY96777,,,ARSEF 23,coh2 (MAA_07838),,,,coh1 (MAA_08820),UniProt: E9F971; GenBank: EFY95676,,568076,Metarhizium robertsii,568076,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,hemocoel,bZip transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34347783,PubMed,10.1371/journal.pbio.3001360,PLoS Biol. 2021 Aug 4;19(8):e3001360,wfang1@zju.edu.cn,COH1 was involved in real hemocoel colonization and COH2 was involved in pathogenicity.,X Zhang 2021,2021,2 genes,Zhang-2021-A novel cascade allows Metarhizium,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18929,PHI:11677,UniProt,A0A559KTE7,GenBank,TVY63263,,,160527,arl3 (FOXG_4440),,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,ADP-ribosylation factor-like protein 3,,,,reduced virulence,,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,34338933,PubMed,10.1007/s10482-021-01628-1,Antonie Van Leeuwenhoek. 2021 Oct;114(10):1619-1632,victor.meza@umich.mx,Arl3 was needed for full virulent phenotype in F. oxysporum f. sp. lycopersici.,C A Araiza-Cervantes 2021,2021,1 gene,Araiza-Cervante-2021-Transcript pattern analys,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18930,PHI:11677,UniProt,A0A559KTE7,GenBank,TVY63263,,,160527,arl3 (FOXG_4440),,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,ADP-ribosylation factor-like protein 3,,,,reduced virulence,,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full,,,YVS,34338933,PubMed,10.1007/s10482-021-01628-1,Antonie Van Leeuwenhoek. 2021 Oct;114(10):1619-1632,victor.meza@umich.mx,Arl3 was needed for full virulent phenotype in F. oxysporum f. sp. lycopersici.,C A Araiza-Cervantes 2021,2021,1 gene,Araiza-Cervante-2021-Transcript pattern analys,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18931,PHI:11678,UniProt,B1MK78,GenBank,EIV67576,,,CCUG 48898,mmpA (MMCCUG48898_0905),,,,,,,36809,Mycobacteroides abscessus,,subsp. massiliense strain CIP 108297,pulmonary infection; cutaneo-mucous infection,rodents,10090,Mus musculus (related: house mouse),SCID; GMCSF knockout mice,,,bone marrow-derived macrophage; spleen; liver; lung,outer membrane porin,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,glutaraldehyde; nitric oxide; clarithromycin; erythromycin; azithromycin; amikacin; cefoxitin; linezolid; tigecycline,glutaraldehyde: CHEBI:64276; nitric oxide: CHEBI:16480; clarithromycin: CHEBI:3732; erythromycin: CHEBI:48923; azithromycin: CHEBI:2955; amikacin: CHEBI:2637; cefoxitin: CHEBI:209807; linezolid: CHEBI:63607; tigecycline: CHEBI:149836,,,,,gene deletion: full; gene complementation,,,YVS,34335541,PubMed,10.3389/fmicb.2021.706207,Front Microbiol. 2021 Jul 14;12:706207,Mary.Jackson@colostate.edu,"Inactivation by allelic replacement of the each of the two Msp-type porin genes of M. abscessus subsp. massiliense CIP108297, mmpA and mmpB, led to a marked increase in the virulence and pathogenicity of both mutants in murine macrophages and infected mice.",V C N de Moura 2021,2021,2 genes,de Moura-2021-Increased Virulence of Outer Mem,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18932,PHI:11679,UniProt,B1MK79,GenBank,EIV67577,,,CCUG 48898,mmpB (MMCCUG48898_0906),,,,,,,36809,Mycobacteroides abscessus,,subsp. massiliense strain CIP 108297,pulmonary infection; cutaneo-mucous infection,rodents,10090,Mus musculus (related: house mouse),SCID; GMCSF knockout mice,,,bone marrow-derived macrophage; spleen; liver; lung,outer membrane porin,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,glutaraldehyde; nitric oxide; clarithromycin; erythromycin; azithromycin; amikacin; cefoxitin; linezolid; tigecycline,glutaraldehyde: CHEBI:64276; nitric oxide: CHEBI:16480; clarithromycin: CHEBI:3732; erythromycin: CHEBI:48923; azithromycin: CHEBI:2955; amikacin: CHEBI:2637; cefoxitin: CHEBI:209807; linezolid: CHEBI:63607; tigecycline: CHEBI:149836,,,,,gene deletion: full; gene complementation,,,YVS,34335541,PubMed,10.3389/fmicb.2021.706207,Front Microbiol. 2021 Jul 14;12:706207,Mary.Jackson@colostate.edu,"Inactivation by allelic replacement of the each of the two Msp-type porin genes of M. abscessus subsp. massiliense CIP108297, mmpA and mmpB, led to a marked increase in the virulence and pathogenicity of both mutants in murine macrophages and infected mice.",V C N de Moura 2021,2021,2 genes,de Moura-2021-Increased Virulence of Outer Mem,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18933,PHI:11680,UniProt,F9F510,GenBank,EGU88002,,,Fo5176,ugmA,,,,,,,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain CGMCC3.2830,Fusarium wilt (cucumber),eudicots,3659,Cucumis sativus (related: Cucumber),cv. Zhong Nong 16,,,seed,putative UDP-galactopyranose mutase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,calcofluor white; Congo red; sorbitol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:17924,,,,,gene deletion: full; gene complementation,,,YVS,34329342,PubMed,10.1371/journal.pone.0250064,PLoS One. 2021 Jul 30;16(7):e0250064,jinc@im.ac.cn,"Although deletion of the ugmB gene did not cause any visible phenotype, deletion of both ugmA and ugmB genes caused more severe phenotypes as compared with the ΔugmA.",H Zhou 2021,2021,3 genes,Zhou-2021-Galactofuranose (Galf)-containing su,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18934,PHI:11681,UniProt,F9FH56,GenBank,EGU83790,,,Fo5176,ugmB,,,,,,,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain CGMCC3.2830,Fusarium wilt (cucumber),eudicots,3659,Cucumis sativus (related: Cucumber),cv. Zhong Nong 16,,,seed,putative UDP-galactopyranose mutase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,calcofluor white; Congo red; sorbitol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:17924,,,,,gene deletion: full; gene complementation,,,YVS,34329342,PubMed,10.1371/journal.pone.0250064,PLoS One. 2021 Jul 30;16(7):e0250064,jinc@im.ac.cn,"Although deletion of the ugmB gene did not cause any visible phenotype, deletion of both ugmA and ugmB genes caused more severe phenotypes as compared with the ΔugmA.",H Zhou 2021,2021,3 genes,Zhou-2021-Galactofuranose (Galf)-containing su,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18935,PHI:11680,UniProt,F9F510,GenBank,EGU88002,,,Fo5176,ugmA,,,,,,PHI:11681,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain CGMCC3.2830,Fusarium wilt (cucumber),eudicots,3659,Cucumis sativus (related: Cucumber),cv. Zhong Nong 16,,,seed,putative UDP-galactopyranose mutase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,calcofluor white; Congo red; sorbitol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:17924,,,,,gene deletion: full; gene complementation,,,YVS,34329342,PubMed,10.1371/journal.pone.0250064,PLoS One. 2021 Jul 30;16(7):e0250064,jinc@im.ac.cn,"Although deletion of the ugmB gene did not cause any visible phenotype, deletion of both ugmA and ugmB genes caused more severe phenotypes as compared with the ΔugmA.",H Zhou 2021,2021,3 genes,Zhou-2021-Galactofuranose (Galf)-containing su,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18936,PHI:11681,UniProt,F9FH56,GenBank,EGU83790,,,Fo5176,ugmB,,,,,,PHI:11680,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain CGMCC3.2830,Fusarium wilt (cucumber),eudicots,3659,Cucumis sativus (related: Cucumber),cv. Zhong Nong 16,,,seed,putative UDP-galactopyranose mutase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,calcofluor white; Congo red; sorbitol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:17924,,,,,gene deletion: full; gene complementation,,,YVS,34329342,PubMed,10.1371/journal.pone.0250064,PLoS One. 2021 Jul 30;16(7):e0250064,jinc@im.ac.cn,"Although deletion of the ugmB gene did not cause any visible phenotype, deletion of both ugmA and ugmB genes caused more severe phenotypes as compared with the ΔugmA.",H Zhou 2021,2021,3 genes,Zhou-2021-Galactofuranose (Galf)-containing su,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18937,PHI:11682,UniProt,F9F8S3,GenBank,EGU86692,,,Fo5176,gfsB,,,,,,,5507,Fusarium oxysporum,5508,f. sp. cucumerinum strain CGMCC3.2830,Fusarium wilt (cucumber),eudicots,3659,Cucumis sativus (related: Cucumber),cv. Zhong Nong 16,,,seed,galatofuranosyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,calcofluor white; Congo red; sorbitol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sorbitol: CHEBI:17924,,,,,gene deletion: full; gene complementation,,,YVS,34329342,PubMed,10.1371/journal.pone.0250064,PLoS One. 2021 Jul 30;16(7):e0250064,jinc@im.ac.cn,The ΔgfsB exhibited an attenuated virulence although no other phenotype was observed.,H Zhou 2021,2021,3 genes,Zhou-2021-Galactofuranose (Galf)-containing su,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18938,PHI:11683,UniProt,A0A0H3B1U8,GenBank,CRY73034,,,SP93422,iucA (ypk_0786),,,,,,,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; intestine; colon; spleen; liver,aerobactin siderophore biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34335534,PubMed,10.3389/fmicb.2021.699913,Front Microbiol. 2021 Jul 15;12:699913,xihuishen@nwsuaf.edu.cn,The aerobactin-producing system contributed to the pathogenicity of Y. pseudotuberculosis by enhancing the ability of colonization in mice.,C Li 2021,2021,2 genes,Li-2021-Aerobactin-Mediated Iron Acquisition E,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18939,PHI:11684,UniProt,A0A0H3B0A1,GenBank,VEG86347,,,NCTC10275,iutA (ypk_0782),chromosome 1,,,,,,633,Yersinia pseudotuberculosis,502800,YPIII,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; intestine; colon; spleen; liver,putative ferric siderophore receptor,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34335534,PubMed,10.3389/fmicb.2021.699913,Front Microbiol. 2021 Jul 15;12:699913,xihuishen@nwsuaf.edu.cn,The aerobactin-producing system contributed to the pathogenicity of Y. pseudotuberculosis by enhancing the ability of colonization in mice.,C Li 2021,2021,2 genes,Li-2021-Aerobactin-Mediated Iron Acquisition E,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18940,PHI:11685,UniProt,A0A2U8QP17,GenBank,AWM11658,,,ZJ5-5,mcr-3,,,,,,,645,Aeromonas salmonicida,29491,AS1,furunculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; heart; liver; spleen; lung; kidney,phosphoethanolamine transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34323389,PubMed,10.1002/advs.202101336,Adv Sci (Weinh). 2021 Sep;8(18):e2101336,sjz@cau.edu.cn,"Compared with the wild-type strains, increased mortality is observed in mice intraperitoneally-infected with mcr-3-positive Aeromonas salmonicida and Escherichia coli strains, along with sepsis symptoms. The increased mortality is tightly associated with the increased tissue hypoxia, injury, and post-inflammation.",W Yin 2021,2021,1 gene,Yin-2021-Mobile Colistin Resistance Enzyme MCR,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18941,PHI:11685,UniProt,A0A2U8QP17,GenBank,AWM11658,,,ZJ5-5,mcr-3,,,,,,,645,Aeromonas salmonicida,29491,AS1,furunculosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,phosphoethanolamine transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34323389,PubMed,10.1002/advs.202101336,Adv Sci (Weinh). 2021 Sep;8(18):e2101336,sjz@cau.edu.cn,"MCR-3 expression induced lipid A decoration may help the bacteria evade phagocytosis, especially by macrophages.",W Yin 2021,2021,1 gene,Yin-2021-Mobile Colistin Resistance Enzyme MCR,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18942,PHI:11686,UniProt,B0FLN1,GenBank,ABY50954,,,M2,abaI,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,acyl-homoserine-lactone synthase,,,,reduced virulence,,,,,,,,reduced,,no,kanamycin; gentamicin; penicillin; streptomycin; meropenem; imipenem; ampicillin; ceftizoxime; cefepime; cefoperazone–sulbactam; piperacillin–tazobactam; vancomycin; tetracycline; spectinomycin,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; vancomycin: CHEBI:28001; penicillin: CHEBI:17334; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968; ampicillin: CHEBI:28971; ceftizoxime: CHEBI:553473; cefoperazone: CHEBI:3493; sulbactam: CHEBI:9321; tetracycline: CHEBI:27902; streptomycin: CHEBI:17076; spectinomycin: CHEBI:9215,,,,,gene deletion: full; gene complementation,,,YVS,34322102,PubMed,10.3389/fmicb.2021.679241,Front Microbiol. 2021 Jul 12;12:679241,lifan@jlu.edu.cn,Deletion of abaR led to the significant repression of abaI.,X Sun 2021,2021,2 genes,Sun-2021-The abaI_abaR Quorum Sensing System E,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18943,PHI:11687,,no data found,GenBank,UDA05730,,,HKU4,abaR,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,LuxR family transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,kanamycin; gentamicin; penicillin; streptomycin; meropenem; imipenem; ampicillin; ceftizoxime; cefepime; cefoperazone–sulbactam; piperacillin–tazobactam; vancomycin; tetracycline; spectinomycin,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; vancomycin: CHEBI:28001; penicillin: CHEBI:17334; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968; ampicillin: CHEBI:28971; ceftizoxime: CHEBI:553473; cefoperazone: CHEBI:3493; sulbactam: CHEBI:9321; tetracycline: CHEBI:27902; streptomycin: CHEBI:17076; spectinomycin: CHEBI:9215,,,,,gene deletion: full; gene complementation,,,YVS,34322102,PubMed,10.3389/fmicb.2021.679241,Front Microbiol. 2021 Jul 12;12:679241,lifan@jlu.edu.cn,Deletion of abaR led to the significant repression of abaI.,X Sun 2021,2021,2 genes,Sun-2021-The abaI_abaR Quorum Sensing System E,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18944,PHI:11686,UniProt,B0FLN1,GenBank,ABY50954,,,M2,abaI,,,,,,PHI:11687,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,acyl-homoserine-lactone synthase,,,,reduced virulence,,,,,,,,wild type,,no,kanamycin; gentamicin; penicillin; streptomycin; meropenem; imipenem; ampicillin; ceftizoxime; cefepime; cefoperazone–sulbactam; piperacillin–tazobactam; vancomycin; tetracycline; spectinomycin,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; vancomycin: CHEBI:28001; penicillin: CHEBI:17334; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968; ampicillin: CHEBI:28971; ceftizoxime: CHEBI:553473; cefoperazone: CHEBI:3493; sulbactam: CHEBI:9321; tetracycline: CHEBI:27902; streptomycin: CHEBI:17076; spectinomycin: CHEBI:9215,,,,,gene deletion: full; gene complementation,,,YVS,34322102,PubMed,10.3389/fmicb.2021.679241,Front Microbiol. 2021 Jul 12;12:679241,lifan@jlu.edu.cn,Deletion of abaR led to the significant repression of abaI.,X Sun 2021,2021,2 genes,Sun-2021-The abaI_abaR Quorum Sensing System E,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18945,PHI:11687,,no data found,GenBank,UDA05730,,,HKU4,abaR,,,,,,PHI:11686,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,LuxR family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,kanamycin; gentamicin; penicillin; streptomycin; meropenem; imipenem; ampicillin; ceftizoxime; cefepime; cefoperazone–sulbactam; piperacillin–tazobactam; vancomycin; tetracycline; spectinomycin,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; vancomycin: CHEBI:28001; penicillin: CHEBI:17334; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968; ampicillin: CHEBI:28971; ceftizoxime: CHEBI:553473; cefoperazone: CHEBI:3493; sulbactam: CHEBI:9321; tetracycline: CHEBI:27902; streptomycin: CHEBI:17076; spectinomycin: CHEBI:9215,,,,,gene deletion: full; gene complementation,,,YVS,34322102,PubMed,10.3389/fmicb.2021.679241,Front Microbiol. 2021 Jul 12;12:679241,lifan@jlu.edu.cn,Deletion of abaR led to the significant repression of abaI.,X Sun 2021,2021,2 genes,Sun-2021-The abaI_abaR Quorum Sensing System E,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18946,PHI:11686,UniProt,B0FLN1,GenBank,ABY50954,,,M2,abaI,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; spleen; lung,acyl-homoserine-lactone synthase,,,,reduced virulence,,,,,,,,reduced,,no,kanamycin; gentamicin; penicillin; streptomycin; meropenem; imipenem; ampicillin; ceftizoxime; cefepime; cefoperazone–sulbactam; piperacillin–tazobactam; vancomycin; tetracycline; spectinomycin,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; vancomycin: CHEBI:28001; penicillin: CHEBI:17334; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968; ampicillin: CHEBI:28971; ceftizoxime: CHEBI:553473; cefoperazone: CHEBI:3493; sulbactam: CHEBI:9321; tetracycline: CHEBI:27902; streptomycin: CHEBI:17076; spectinomycin: CHEBI:9215,,,,,gene deletion: full; gene complementation,,,YVS,34322102,PubMed,10.3389/fmicb.2021.679241,Front Microbiol. 2021 Jul 12;12:679241,lifan@jlu.edu.cn,Deletion of abaR led to the significant repression of abaI.,X Sun 2021,2021,2 genes,Sun-2021-The abaI_abaR Quorum Sensing System E,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18947,PHI:11687,,no data found,GenBank,UDA05730,,,HKU4,abaR,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; spleen; lung,LuxR family transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,kanamycin; gentamicin; penicillin; streptomycin; meropenem; imipenem; ampicillin; ceftizoxime; cefepime; cefoperazone–sulbactam; piperacillin–tazobactam; vancomycin; tetracycline; spectinomycin,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; vancomycin: CHEBI:28001; penicillin: CHEBI:17334; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968; ampicillin: CHEBI:28971; ceftizoxime: CHEBI:553473; cefoperazone: CHEBI:3493; sulbactam: CHEBI:9321; tetracycline: CHEBI:27902; streptomycin: CHEBI:17076; spectinomycin: CHEBI:9215,,,,,gene deletion: full; gene complementation,,,YVS,34322102,PubMed,10.3389/fmicb.2021.679241,Front Microbiol. 2021 Jul 12;12:679241,lifan@jlu.edu.cn,Deletion of abaR led to the significant repression of abaI.,X Sun 2021,2021,2 genes,Sun-2021-The abaI_abaR Quorum Sensing System E,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18948,PHI:11686,UniProt,B0FLN1,GenBank,ABY50954,,,M2,abaI,,,,,,PHI:11687,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; spleen; lung,acyl-homoserine-lactone synthase,,,,reduced virulence,,,,,,,,wild type,,no,kanamycin; gentamicin; penicillin; streptomycin; meropenem; imipenem; ampicillin; ceftizoxime; cefepime; cefoperazone–sulbactam; piperacillin–tazobactam; vancomycin; tetracycline; spectinomycin,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; vancomycin: CHEBI:28001; penicillin: CHEBI:17334; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968; ampicillin: CHEBI:28971; ceftizoxime: CHEBI:553473; cefoperazone: CHEBI:3493; sulbactam: CHEBI:9321; tetracycline: CHEBI:27902; streptomycin: CHEBI:17076; spectinomycin: CHEBI:9215,,,,,gene deletion: full; gene complementation,,,YVS,34322102,PubMed,10.3389/fmicb.2021.679241,Front Microbiol. 2021 Jul 12;12:679241,lifan@jlu.edu.cn,Deletion of abaR led to the significant repression of abaI.,X Sun 2021,2021,2 genes,Sun-2021-The abaI_abaR Quorum Sensing System E,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18949,PHI:11687,,no data found,GenBank,UDA05730,,,HKU4,abaR,,,,,,PHI:11686,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; spleen; lung,LuxR family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,kanamycin; gentamicin; penicillin; streptomycin; meropenem; imipenem; ampicillin; ceftizoxime; cefepime; cefoperazone–sulbactam; piperacillin–tazobactam; vancomycin; tetracycline; spectinomycin,kanamycin: CHEBI:6104; gentamicin: CHEBI:17833; vancomycin: CHEBI:28001; penicillin: CHEBI:17334; piperacillin: CHEBI:8232; tazobactam: CHEBI:9421; cefepime: CHEBI:478164; imipenem: CHEBI:471744; meropenem: CHEBI:43968; ampicillin: CHEBI:28971; ceftizoxime: CHEBI:553473; cefoperazone: CHEBI:3493; sulbactam: CHEBI:9321; tetracycline: CHEBI:27902; streptomycin: CHEBI:17076; spectinomycin: CHEBI:9215,,,,,gene deletion: full; gene complementation,,,YVS,34322102,PubMed,10.3389/fmicb.2021.679241,Front Microbiol. 2021 Jul 12;12:679241,lifan@jlu.edu.cn,Deletion of abaR led to the significant repression of abaI.,X Sun 2021,2021,2 genes,Sun-2021-The abaI_abaR Quorum Sensing System E,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18950,PHI:11688,UniProt,A0A0F2MLM2,GenBank,KJR89086,,,1099-18,rmlD (SPSK_0645),,,,,,,29908,Sporothrix schenckii,,Xc,sporotrichosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,methionine adenosyltransferase 2 subunit beta,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34308006,PubMed,10.1016/j.tcsw.2021.100058,Cell Surf. 2021 Jun 26;7:100058,soulk_taca@hotmail.com,RmlD silencing negatively affected the S. schenckii ability to kill G. mellonella larvae and the ability to stimulate insect immune effectors.,A K Tamez-Castrellón 2021,2021,1 gene,Tamez-Castrelló-2021-Disruption of protein rha,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18951,PHI:11688,UniProt,A0A0F2MLM2,GenBank,KJR89086,,,1099-18,rmlD (SPSK_0645),,,,,,,29908,Sporothrix schenckii,,Xc,sporotrichosis,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell; macrophage,methionine adenosyltransferase 2 subunit beta,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34308006,PubMed,10.1016/j.tcsw.2021.100058,Cell Surf. 2021 Jun 26;7:100058,soulk_taca@hotmail.com,"Upon incubation with human monocyte-derived macrophages, the silenced strains were more efficiently phagocytosed than the wild-type strain.",A K Tamez-Castrellón 2021,2021,1 gene,Tamez-Castrelló-2021-Disruption of protein rha,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18952,PHI:11689,UniProt,G4YYH1,GenBank,EGZ24558,,,P6497,GRASP55_65 (PsGRASP),,,,,,,67593,Phytophthora sojae,1094619,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Hefeng 47,,,seedling,golgi reassembly stacking protein,,,,reduced virulence,,,yes,yes,,,aberrant,reduced,,no,H2O2; tunicamycin; dithiothreitol,H2O2: CHEBI:16240; tunicamycin (TM): CHEBI:29699; dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,34305870,PubMed,10.3389/fmicb.2021.702632,Front Microbiol. 2021 Jul 8;12:702632,ddou@njau.edu.cn,"The mutant exhibited impaired vegetative growth, zoospore release and virulence.",J Si 2021,2021,1 gene,"Si-2021-PsGRASP, a Golgi Reassembly Stacking P",BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18953,PHI:11690,UniProt,A0A0Z8F7P5,GenBank,CYU75433,,,LSS52,pepO,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,endopeptidase O,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34305859,PubMed,10.3389/fmicb.2021.694103,Front Microbiol. 2021 Jul 8;12:694103,beiwc@mail.hzau.edu.cn,The SspepO-deficient mutant had a lower mortality rate than the wildtype strain in a mouse model.,Y Zhou 2021,2021,1 gene,Zhou-2021-Binding of Plasminogen to Streptococ,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18954,PHI:11690,UniProt,A0A0Z8F7P5,GenBank,CYU75433,,,LSS52,pepO,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),,,,blood; serum,endopeptidase O,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34305859,PubMed,10.3389/fmicb.2021.694103,Front Microbiol. 2021 Jul 8;12:694103,beiwc@mail.hzau.edu.cn,The SspepO-deficient mutant was efficiently killed by human serum and blood.,Y Zhou 2021,2021,1 gene,Zhou-2021-Binding of Plasminogen to Streptococ,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18955,PHI:11690,UniProt,A0A0Z8F7P5,GenBank,CYU75433,,,LSS52,pepO,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10117,Rattus rattus (related: black rat),,,,brain microvessel endothelial cell,endopeptidase O,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34305859,PubMed,10.3389/fmicb.2021.694103,Front Microbiol. 2021 Jul 8;12:694103,beiwc@mail.hzau.edu.cn,SspepO-deficient mutant showed impaired adherence to plasminogen as well as impaired adherence to and invasion of rat brain microvascular endothelial cells compared with the wildtype strain.,Y Zhou 2021,2021,1 gene,Zhou-2021-Binding of Plasminogen to Streptococ,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18956,PHI:11691,UniProt,Q83YM3,GenBank,AAF71481,,,strain 61,HopA1,,,,,,,317,Pseudomonas syringae,,pv. syringae strain 61,bacterial speck (tomato),eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,34299060,PubMed,10.3390/ijms22147440,Int J Mol Sci. 2021 Jul 12;22(14):7440,kishor.ingole@rcb.res.in,"In Arabidopsis thaliana, RESISTANCE TO PSEUDOMONAS SYRINGAE 6 (RPS6) gene confered effector-triggered immunity (ETI) against HopA1pss derived from P. syringae pv. syringae strain 61.",S K Dahale 2021,2021,1 gene,Dahale-2021-HopA1 Effector from Pseudomonas sy,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18957,PHI:11691,UniProt,Q83YM3,GenBank,AAF71481,,,strain 61,HopA1,,,,,,,317,Pseudomonas syringae,,pv. syringae strain 61,bacterial speck (tomato),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Xanthi,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,34299060,PubMed,10.3390/ijms22147440,Int J Mol Sci. 2021 Jul 12;22(14):7440,kishor.ingole@rcb.res.in,"In Arabidopsis thaliana, RESISTANCE TO PSEUDOMONAS SYRINGAE 6 (RPS6) gene confered effector-triggered immunity (ETI) against HopA1pss derived from P. syringae pv. syringae strain 61.",S K Dahale 2021,2021,1 gene,Dahale-2021-HopA1 Effector from Pseudomonas sy,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18958,PHI:11691,UniProt,Q83YM3,GenBank,AAF71481,,,strain 61,HopA1,,,,,,,317,Pseudomonas syringae,,pv. syringae strain 61,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,34299060,PubMed,10.3390/ijms22147440,Int J Mol Sci. 2021 Jul 12;22(14):7440,kishor.ingole@rcb.res.in,"In Arabidopsis thaliana, RESISTANCE TO PSEUDOMONAS SYRINGAE 6 (RPS6) gene confered effector-triggered immunity (ETI) against HopA1pss derived from P. syringae pv. syringae strain 61.",S K Dahale 2021,2021,1 gene,Dahale-2021-HopA1 Effector from Pseudomonas sy,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18959,PHI:11692,,no data found,GenBank,WP_014540369,,,,plzA,,,,,,,139,Borreliella burgdorferi,224326,B31 A3-68,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,C-di-GMP-binding receptor,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34265024,PubMed,10.1371/journal.ppat.1009725,PLoS Pathog. 2021 Jul 15;17(7):e1009725,Mcaima@uchc.edu,Loss of PlzA markedly impaired spirochete infectivity in a c-di-GMP independent manner.,A M Groshong 2021,2021,1 gene,Groshong-2021-PlzA is a bifunctional c-di-GMP,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18960,PHI:11692,,no data found,GenBank,WP_014540369,,,,plzA,,R145D,,,,,139,Borreliella burgdorferi,224326,B31 A3-68,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,C-di-GMP-binding receptor,,,,unaffected pathogenicity,,,,,,,,reduced; aberrant,,no,,,,,,,gene mutation; gene complementation,,,YVS,34265024,PubMed,10.1371/journal.ppat.1009725,PLoS Pathog. 2021 Jul 15;17(7):e1009725,Mcaima@uchc.edu,Loss of PlzA markedly impaired spirochete infectivity in a c-di-GMP independent manner.,A M Groshong 2021,2021,1 gene,Groshong-2021-PlzA is a bifunctional c-di-GMP,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18961,PHI:11693,UniProt,P0AA16,GenBank,AAC76430,,,K-12,ompR,,,,,,,562,Escherichia coli,511145,MG1655,infection,primates,9606,Homo sapiens (related: human),T84 cell line,,,intestinal epithelial cell,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34262546,PubMed,10.3389/fmicb.2021.684473,Front Microbiol. 2021 Jun 28;12:684473,vincent.trebosc@bioversys.com,"Deletion of ompR compromised the ability of AIEC strains to cope with the stress induced by bile salts, which may be key for AIEC pathogenesis.",V Lucchini 2021,2021,1 gene,Lucchini-2021-The Role of OmpR in Bile Toleran,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18962,PHI:11693,UniProt,P0AA16,GenBank,AAC76430,,,K-12,ompR,,,,,,,562,Escherichia coli,511145,MG1655,infection,rodents,10090,Mus musculus (related: house mouse),CEABAC10,,,gut,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34262546,PubMed,10.3389/fmicb.2021.684473,Front Microbiol. 2021 Jun 28;12:684473,vincent.trebosc@bioversys.com,"Deletion of ompR compromised the ability of AIEC strains to cope with the stress induced by bile salts, which may be key for AIEC pathogenesis.",V Lucchini 2021,2021,1 gene,Lucchini-2021-The Role of OmpR in Bile Toleran,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18963,PHI:11694,UniProt,no data found,GenBank,,,,,PYO,,,,,,,287,Pseudomonas aeruginosa,,,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,"pyocyanin (PYO), a major virulence factor",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34278675,PubMed,10.1111/jcmm.16788,J Cell Mol Med. 2021 Aug;25(15):7524-7537,wangjinsmc@sina.com,"PYO was found to induce autophagy in macrophages, by up- regulation of HMGN2 acetylation (HMGN2ac) and the down- regulation of H3K27 acetylation (H3K27ac).",Y Du 2021,2021,1 gene,Du-2021-The regulatory effect of acetylation o,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18964,PHI:11694,UniProt,no data found,GenBank,,,,,PYO,,,,,,,287,Pseudomonas aeruginosa,,,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"pyocyanin (PYO), a major virulence factor",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34278675,PubMed,10.1111/jcmm.16788,J Cell Mol Med. 2021 Aug;25(15):7524-7537,wangjinsmc@sina.com,"PYO was found to induce autophagy in macrophages, by up- regulation of HMGN2 acetylation (HMGN2ac) and the down- regulation of H3K27 acetylation (H3K27ac).",Y Du 2021,2021,1 gene,Du-2021-The regulatory effect of acetylation o,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18965,PHI:11694,UniProt,no data found,GenBank,,,,,PYO,,,,,,,287,Pseudomonas aeruginosa,,,opportunistic infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,"pyocyanin (PYO), a major virulence factor",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34278675,PubMed,10.1111/jcmm.16788,J Cell Mol Med. 2021 Aug;25(15):7524-7537,wangjinsmc@sina.com,"PYO was found to induce autophagy in macrophages, by up- regulation of HMGN2 acetylation (HMGN2ac) and the down- regulation of H3K27 acetylation (H3K27ac).",Y Du 2021,2021,1 gene,Du-2021-The regulatory effect of acetylation o,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18966,PHI:11695,UniProt,A0A4Q4NB74,GenBank,RYN72463,,,FERA 1177,pex6,,,,,,,5599,Alternaria alternata,,,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),cv. Blanco,,,leaf,peroxisomal biogenesis factor 6,,,,reduced virulence,,,,,,,,reduced,,no,"H2O2; 2-chloro-5-hydroxypyridine; eosin Y; rose bengal; 2,3,5-triiodobenzoic acid","H2O2: CHEBI:16240; 2-chloro-5-hydroxypyridine cas no.: CAS:41288-96-4; eosin Y: CHEBI:52053; rose bengal: CHEBI:52261; 2,3,5-triiodobenzoic acid: CHEBI:73175",,,,,gene deletion: full; gene complementation,,,YVS,34262533,PubMed,10.3389/fmicb.2021.645792,Front Microbiol. 2021 Jun 28;12:645792,krchung@nchu.edu.tw,"Adding biotin, oleate, and iron in combination fully restored the growth of the pex6-deficient mutant (Δpex6), but failed to restore Δpex6 virulence to citrus.",P C Wu 2021,2021,1 gene,Wu-2021-Peroxisomes Implicated in the Biosynth,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18967,PHI:11696,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,,287,Pseudomonas aeruginosa,,,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),,,,lung,transcriptional activator protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34250084,PubMed,10.15698/mic2021.07.755,Microb Cell. 2021 May 31;8(7):161-163,dao.nguyen@mcgill.ca,"LasR variants induced higher levels of pro-inflammatory cytokines, increased airway epithelial mICAM-1 expression as well as greater neutrophilic inflammation and lung pathology than wild-type infections.",L C Hennemann 2021,2021,1 gene,Hennemann-2021-LasR-regulated proteases in acu,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18968,PHI:11697,UniProt,no data found,GenBank,,,,,Mlp37347,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,4100,Nicotiana benthamiana (no common name found)(non-host bioassay),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,34204123,PubMed,10.3390/microorganisms9061232,Microorganisms. 2021 Jun 6;9(6):1232,hugo.germain@uqtr.ca,"In infection assays, the effector promoted Hyalonoperospora arabidopsidis growth but not bacterial growth.",M S Rahman 2021,2021,1 gene,Rahman-2021-The Fungal Effector Mlp37347 Alter,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18969,PHI:11697,UniProt,no data found,GenBank,,,,,Mlp37347,,,,,,,203908,Melampsora laricis-populina,747676,98AG31,leaf rust (poplar),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,34204123,PubMed,10.3390/microorganisms9061232,Microorganisms. 2021 Jun 6;9(6):1232,hugo.germain@uqtr.ca,"In infection assays, the effector promoted Hyalonoperospora arabidopsidis growth but not bacterial growth.",M S Rahman 2021,2021,1 gene,Rahman-2021-The Fungal Effector Mlp37347 Alter,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18970,PHI:11698,UniProt,P18177,GenBank,CAA37298,,,VPI 10463,tcdB,,TcdBCSPG4− (CSPG4-binding deficient TcdB variant),,,,,1496,Clostridioides difficile,,VPI10463,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,exotoxin B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34145250,PubMed,10.1038/s41467-021-23878-3,Nat Commun. 2021 Jun 18;12(1):3748,min.dong@childrens.harvard.edu,"Mutations that selectively disrupted CSPG4 binding reduce TcdB toxicity in mice, while CSPG4-knockout mice show reduced damage to colonic tissues during C. difficile infections. Host gene alteration data available for CSPG4.",P Chen 2021,2021,1 gene,Chen-2021-Structural basis for CSPG4 as a rece,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18971,PHI:11698,UniProt,P18177,GenBank,CAA37298,,,VPI 10463,tcdB,,TcdBFZD− (FZD-binding deficient TcdB variant),,,,,1496,Clostridioides difficile,,VPI10463,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; colon,exotoxin B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34145250,PubMed,10.1038/s41467-021-23878-3,Nat Commun. 2021 Jun 18;12(1):3748,min.dong@childrens.harvard.edu,"Mutations that selectively disrupted CSPG4 binding reduce TcdB toxicity in mice, while CSPG4-knockout mice show reduced damage to colonic tissues during C. difficile infections. Host gene alteration data available for CSPG4.",P Chen 2021,2021,1 gene,Chen-2021-Structural basis for CSPG4 as a rece,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18972,PHI:11699,UniProt,Q9HU60,GenBank,AE004925_7,,,PAO1,ntrB,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; nasal cavity,histidine kinase,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin,ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,YVS,34249781,PubMed,10.3389/fcimb.2021.694789,Front Cell Infect Microbiol. 2021 Jun 24;11:694789,bob@hancocklab.com,"P. aeruginosa mutant strains (ΔntrB, ΔntrC and ΔntrBC) colonized the skin but not the respiratory tract of mice as well as WT and, unlike WT, could be reduced or eradicated from the skin by ciprofloxacin.",M A Alford 2021,2021,2 genes,Alford-2021-NtrBC Selectively Regulates Host-P,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18973,PHI:11700,UniProt,Q9HU59,GenBank,AE004925_8,,,PAO1,ntrC,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; nasal cavity,DNA-binding transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin,ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,YVS,34249781,PubMed,10.3389/fcimb.2021.694789,Front Cell Infect Microbiol. 2021 Jun 24;11:694789,bob@hancocklab.com,"P. aeruginosa mutant strains (ΔntrB, ΔntrC and ΔntrBC) colonized the skin but not the respiratory tract of mice as well as WT and, unlike WT, could be reduced or eradicated from the skin by ciprofloxacin.",M A Alford 2021,2021,2 genes,Alford-2021-NtrBC Selectively Regulates Host-P,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18974,PHI:11699,UniProt,Q9HU60,GenBank,AE004925_7,,,PAO1,ntrB,,,,,,PHI:11700,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; nasal cavity,histidine kinase,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin,ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,YVS,34249781,PubMed,10.3389/fcimb.2021.694789,Front Cell Infect Microbiol. 2021 Jun 24;11:694789,bob@hancocklab.com,"P. aeruginosa mutant strains (ΔntrB, ΔntrC and ΔntrBC) colonized the skin but not the respiratory tract of mice as well as WT and, unlike WT, could be reduced or eradicated from the skin by ciprofloxacin.",M A Alford 2021,2021,2 genes,Alford-2021-NtrBC Selectively Regulates Host-P,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18975,PHI:11700,UniProt,Q9HU59,GenBank,AE004925_8,,,PAO1,ntrC,,,,,,PHI:11699,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; nasal cavity,DNA-binding transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin,ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,YVS,34249781,PubMed,10.3389/fcimb.2021.694789,Front Cell Infect Microbiol. 2021 Jun 24;11:694789,bob@hancocklab.com,"P. aeruginosa mutant strains (ΔntrB, ΔntrC and ΔntrBC) colonized the skin but not the respiratory tract of mice as well as WT and, unlike WT, could be reduced or eradicated from the skin by ciprofloxacin.",M A Alford 2021,2021,2 genes,Alford-2021-NtrBC Selectively Regulates Host-P,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18976,PHI:11699,UniProt,Q9HU60,GenBank,AE004925_7,,,PAO1,ntrB,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,primates,9606,Homo sapiens (related: human),HBE cell line,,,bronchial epithelial cell line,histidine kinase,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin,ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,YVS,34249781,PubMed,10.3389/fcimb.2021.694789,Front Cell Infect Microbiol. 2021 Jun 24;11:694789,bob@hancocklab.com,"P. aeruginosa ΔntrB, ΔntrC and ΔntrBC also exhibited distinct host interactions, including modestly increased cytotoxicity toward human bronchial epithelial cells, reduced virulence factor production and 10-fold increased uptake by macrophages.",M A Alford 2021,2021,2 genes,Alford-2021-NtrBC Selectively Regulates Host-P,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18977,PHI:11700,UniProt,Q9HU59,GenBank,AE004925_8,,,PAO1,ntrC,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,primates,9606,Homo sapiens (related: human),HBE cell line,,,bronchial epithelial cell line,DNA-binding transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin,ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,YVS,34249781,PubMed,10.3389/fcimb.2021.694789,Front Cell Infect Microbiol. 2021 Jun 24;11:694789,bob@hancocklab.com,"P. aeruginosa ΔntrB, ΔntrC and ΔntrBC also exhibited distinct host interactions, including modestly increased cytotoxicity toward human bronchial epithelial cells, reduced virulence factor production and 10-fold increased uptake by macrophages.",M A Alford 2021,2021,2 genes,Alford-2021-NtrBC Selectively Regulates Host-P,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18978,PHI:11699,UniProt,Q9HU60,GenBank,AE004925_7,,,PAO1,ntrB,,,,,,PHI:11700,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,primates,9606,Homo sapiens (related: human),HBE cell line,,,bronchial epithelial cell line,histidine kinase,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin,ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,YVS,34249781,PubMed,10.3389/fcimb.2021.694789,Front Cell Infect Microbiol. 2021 Jun 24;11:694789,bob@hancocklab.com,"P. aeruginosa ΔntrB, ΔntrC and ΔntrBC also exhibited distinct host interactions, including modestly increased cytotoxicity toward human bronchial epithelial cells, reduced virulence factor production and 10-fold increased uptake by macrophages.",M A Alford 2021,2021,2 genes,Alford-2021-NtrBC Selectively Regulates Host-P,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18979,PHI:11700,UniProt,Q9HU59,GenBank,AE004925_8,,,PAO1,ntrC,,,,,,PHI:11699,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,primates,9606,Homo sapiens (related: human),HBE cell line,,,bronchial epithelial cell line,DNA-binding transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin,ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,YVS,34249781,PubMed,10.3389/fcimb.2021.694789,Front Cell Infect Microbiol. 2021 Jun 24;11:694789,bob@hancocklab.com,"P. aeruginosa ΔntrB, ΔntrC and ΔntrBC also exhibited distinct host interactions, including modestly increased cytotoxicity toward human bronchial epithelial cells, reduced virulence factor production and 10-fold increased uptake by macrophages.",M A Alford 2021,2021,2 genes,Alford-2021-NtrBC Selectively Regulates Host-P,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18980,PHI:11701,UniProt,no data found,GenBank,,,,,SC0368,,,,,,,28901,Salmonella enterica,938142,subsp. enterica serovar Choleraesuis strain ATCC 10708,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,hypothetical protein,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34225670,PubMed,10.1186/s12864-021-07759-z,BMC Genomics. 2021 Jul 5;22(1):507,xmshi@sjtu.edu.cn,"The cell invasion capacity increased with the deletion of SC0595 (Δ0595), weakened with deletion of SC0368 (Δ0368 and Δ0368Δ0595).",X Zhou 2021,2021,2 genes,Zhou-2021-Two homologous Salmonella serogroup,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18981,PHI:11702,UniProt,no data found,GenBank,,,,,SC0595,,,,,,,28901,Salmonella enterica,938142,subsp. enterica serovar Choleraesuis strain ATCC 10708,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34225670,PubMed,10.1186/s12864-021-07759-z,BMC Genomics. 2021 Jul 5;22(1):507,xmshi@sjtu.edu.cn,"The cell invasion capacity increased with the deletion of SC0595 (Δ0595), weakened with deletion of SC0368 (Δ0368 and Δ0368Δ0595).",X Zhou 2021,2021,2 genes,Zhou-2021-Two homologous Salmonella serogroup,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18982,PHI:11701,UniProt,no data found,GenBank,,,,,SC0368,,,,,,PHI:11702,28901,Salmonella enterica,938142,subsp. enterica serovar Choleraesuis strain ATCC 10708,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,hypothetical protein,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34225670,PubMed,10.1186/s12864-021-07759-z,BMC Genomics. 2021 Jul 5;22(1):507,xmshi@sjtu.edu.cn,"The cell invasion capacity increased with the deletion of SC0595 (Δ0595), weakened with deletion of SC0368 (Δ0368 and Δ0368Δ0595).",X Zhou 2021,2021,2 genes,Zhou-2021-Two homologous Salmonella serogroup,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18983,PHI:11702,UniProt,no data found,GenBank,,,,,SC0595,,,,,,PHI:11701,28901,Salmonella enterica,938142,subsp. enterica serovar Choleraesuis strain ATCC 10708,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,colonic epithelial cell,hypothetical protein,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34225670,PubMed,10.1186/s12864-021-07759-z,BMC Genomics. 2021 Jul 5;22(1):507,xmshi@sjtu.edu.cn,"The cell invasion capacity increased with the deletion of SC0595 (Δ0595), weakened with deletion of SC0368 (Δ0368 and Δ0368Δ0595).",X Zhou 2021,2021,2 genes,Zhou-2021-Two homologous Salmonella serogroup,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18984,PHI:11703,UniProt,A0A3L6L8J2,GenBank,RHW72386,,,IVM-t1,isp2,,,,,,,5691,Trypanosoma brucei,31286,subsp. rhodesiense strain IL1852,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,blood; hindleg; spleen,ecotin-like inhibitors of serine peptidase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34153047,PubMed,10.1371/journal.pntd.0009526,PLoS Negl Trop Dis. 2021 Jun 21;15(6):e0009526,anapaula@biof.ufrj.br,ISP2 contributed to T. b. rhodesiense virulence in mice and attenuates the inflammatory response during early infection.,D J Levy 2021,2021,1 gene,Levy-2021-Role of the inhibitor of serine pept,BATCH_108B,2021-10-01,MC,,,,,,,,,,,,,
,,Record 18985,PHI:11704,UniProt,A0A0D1E6R6,GenBank,KIS71589,,,521,vmp1 (UMAG_00032),chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,virulence-associated membrane protein,,,,reduced virulence,,,,yes (reduced),,,,,,no,NaCl; sorbitol; calcofluor white; H2O2,NaCl: CHEBI:267101; sorbitol: CHEBI:17924; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34093627,PubMed,10.3389/fpls.2021.669835,Front Plant Sci. 2021 May 21;12:669835,altegoer@uni-marburg.de,The large and partially unstructured C-terminal domain of Vmp2 was crucial for virulence while not contributing to dimerization.,P Weiland 2021,2021,2 genes,Weiland-2021-Identification and Characterizati,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18986,PHI:11705,UniProt,A0A0D1CVX2,GenBank,KIS70518,,,521,vmp2 (UMAG_01689),chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,virulence-associated membrane protein,,,,reduced virulence,,,,,,,,,,no,NaCl; sorbitol; calcofluor white; H2O2,NaCl: CHEBI:267101; sorbitol: CHEBI:17924; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34093627,PubMed,10.3389/fpls.2021.669835,Front Plant Sci. 2021 May 21;12:669835,altegoer@uni-marburg.de,The large and partially unstructured C-terminal domain of Vmp2 was crucial for virulence while not contributing to dimerization.,P Weiland 2021,2021,2 genes,Weiland-2021-Identification and Characterizati,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18987,PHI:11706,UniProt,P0AC26,GenBank,AAC76392,,,K-12 substr. MG1655,nirC,,,,,,,562,Escherichia coli,,APEC XM,infection,rodents,10090,Mus musculus (related: house mouse),b.End3 cell line,,,brain microvascular endothelial cell,nitrite transporter,,,,reduced virulence,,,,,,,,,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34091701,PubMed,10.1007/s00203-021-02412-5,Arch Microbiol. 2021 Sep;203(7):4221-4231,yzgqzhu@yzu.edu.cn,"The nirC gene deletion mutant enhanced ability of motility, decreased in biofilm formation, and it markedly reduced ability to adhere mouse brain microvascular endothelial cell b.End3 cells.",J Liu 2021,2021,1 gene,Liu-2021-Mechanism of nitrite transporter NirC,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18988,PHI:11707,UniProt,Q6Q877,GenBank,AAS92551,,,,SirZ,,,,,,,5022,Leptosphaeria maculans,,D5,blackleg,eudicots,3708,Brassica napus (related: rape),cv. Westar,,,cotyledon,transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34111151,PubMed,10.1371/journal.pone.0252333,PLoS One. 2021 Jun 10;16(6):e0252333,alexander.idnurm@unimelb.edu.au,The sirZ over-expression strains had a major reduction in pathogenicity.,A S Urquhart 2021,2021,2 genes,Urquhart-2021-Constitutive expression of trans,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18989,PHI:11708,UniProt,A4F4L2,GenBank,CAJ90695,,,v23.1.3,AvrLm6,,,,,,,5022,Leptosphaeria maculans,,D5,blackleg,eudicots,3708,Brassica napus (related: rape),cv. Westar,,,cotyledon,transcription factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34111151,PubMed,10.1371/journal.pone.0252333,PLoS One. 2021 Jun 10;16(6):e0252333,alexander.idnurm@unimelb.edu.au,The sirZ over-expression strains had a major reduction in pathogenicity.,A S Urquhart 2021,2021,2 genes,Urquhart-2021-Constitutive expression of trans,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18990,PHI:11708,UniProt,A4F4L2,GenBank,CAJ90695,,,v23.1.3,AvrLm6,,,,,,,5022,Leptosphaeria maculans,,D5,blackleg,eudicots,3707,Brassica juncea (related: brown mustard),cv. Aurea,,,cotyledon,transcription factor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34111151,PubMed,10.1371/journal.pone.0252333,PLoS One. 2021 Jun 10;16(6):e0252333,alexander.idnurm@unimelb.edu.au,The sirZ over-expression strains had a major reduction in pathogenicity.,A S Urquhart 2021,2021,2 genes,Urquhart-2021-Constitutive expression of trans,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18991,PHI:11709,UniProt,A0A1B7Y7A9,GenBank,OBR07942,,,IMI 349063,ChHxt1 (XP_018156460),chromosome 6,,,,,,80884,Colletotrichum higginsianum,,CH-1,anthracnose,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,hexose transporter,,,,unaffected pathogenicity,,no,no,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34073109,PubMed,10.3390/ijms22115963,Int J Mol Sci. 2021 May 31;22(11):5963,luzheng@mail.hzau.edu.cn,Virulence of ΔChHxt4 and ΔChHxt6 were significantly decreased and formed fewer necrotic lesions on leaves.,Q Yuan 2021,2021,6 genes,Yuan-2021-A Novel Hexose Transporter ChHxt6 Is,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18992,PHI:11710,UniProt,H1V442,GenBank,OBR12953,,,IMI 349063,ChHxt2 (XP_018161470),chromosome 3,,,,,,80884,Colletotrichum higginsianum,,CH-1,anthracnose,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,hexose transporter,,,,unaffected pathogenicity,,no,no,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34073109,PubMed,10.3390/ijms22115963,Int J Mol Sci. 2021 May 31;22(11):5963,luzheng@mail.hzau.edu.cn,Virulence of ΔChHxt4 and ΔChHxt6 were significantly decreased and formed fewer necrotic lesions on leaves.,Q Yuan 2021,2021,6 genes,Yuan-2021-A Novel Hexose Transporter ChHxt6 Is,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18993,PHI:11711,UniProt,A0A1B7Y872,GenBank,OBR08236,,,IMI 349063,ChHxt3 (XP_018156754),chromosome 5,,,,,,80884,Colletotrichum higginsianum,,CH-1,anthracnose,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,hexose transporter,,,,unaffected pathogenicity,,no,no,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34073109,PubMed,10.3390/ijms22115963,Int J Mol Sci. 2021 May 31;22(11):5963,luzheng@mail.hzau.edu.cn,Virulence of ΔChHxt4 and ΔChHxt6 were significantly decreased and formed fewer necrotic lesions on leaves.,Q Yuan 2021,2021,6 genes,Yuan-2021-A Novel Hexose Transporter ChHxt6 Is,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18994,PHI:11712,UniProt,H1UYP0,GenBank,OBR10076,,,IMI 349063,ChHxt4 (XP_018158593),chromosome 4,,,,,,80884,Colletotrichum higginsianum,,CH-1,anthracnose,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,hexose transporter,,,,reduced virulence,,no,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34073109,PubMed,10.3390/ijms22115963,Int J Mol Sci. 2021 May 31;22(11):5963,luzheng@mail.hzau.edu.cn,Virulence of ΔChHxt4 and ΔChHxt6 were significantly decreased and formed fewer necrotic lesions on leaves.,Q Yuan 2021,2021,6 genes,Yuan-2021-A Novel Hexose Transporter ChHxt6 Is,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18995,PHI:11713,UniProt,H1VJG6,GenBank,OBR05559,,,IMI 349063,ChHxt5 (XP_018154077),chromosome 8,,,,,,80884,Colletotrichum higginsianum,,CH-1,anthracnose,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,hexose transporter,,,,unaffected pathogenicity,,no,no,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34073109,PubMed,10.3390/ijms22115963,Int J Mol Sci. 2021 May 31;22(11):5963,luzheng@mail.hzau.edu.cn,Virulence of ΔChHxt4 and ΔChHxt6 were significantly decreased and formed fewer necrotic lesions on leaves.,Q Yuan 2021,2021,6 genes,Yuan-2021-A Novel Hexose Transporter ChHxt6 Is,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18996,PHI:11714,UniProt,A0A1B7XWH6,GenBank,OBR04109,,,IMI 349063,ChHxt6 (XP_018152627),chromosome 9,,,,,,80884,Colletotrichum higginsianum,,CH-1,anthracnose,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,leaf,hexose transporter,,,,reduced virulence,,no,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34073109,PubMed,10.3390/ijms22115963,Int J Mol Sci. 2021 May 31;22(11):5963,luzheng@mail.hzau.edu.cn,Virulence of ΔChHxt4 and ΔChHxt6 were significantly decreased and formed fewer necrotic lesions on leaves.,Q Yuan 2021,2021,6 genes,Yuan-2021-A Novel Hexose Transporter ChHxt6 Is,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18997,PHI:11715,UniProt,X0KJP1,GenBank,42027094,,,,FocM35_1 (FOIG_01919),,,,,,,5507,Fusarium oxysporum,1089451,f. sp. cubense TR4 strain II5,wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),AAA group cv. Brazilian,,,leaf; root,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,NaCl; H2O2,NaCl: CHEBI:267101; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34072465,PubMed,10.3390/pathogens10060670,Pathogens. 2021 May 29;10(6):670,liusiwen@gdaas.cn,FocM35_1 knockout mutant compromised the virulence of Foc TR4.,X Zhang 2021,2021,1 gene,Zhang-2021-The M35 Metalloprotease Effector Fo,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18998,PHI:11716,UniProt,G2WZM1,GenBank,EGY22023,,,VdLs.17,ExoPG (VDAG_03463),chromosome 6,,,,,,27337,Verticillium dahliae,,Vd1396-9,vascular wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. Kennebec,,,leaf; stem,exopolygalacturonase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34071016,PubMed,10.3390/pathogens10060642,Pathogens. 2021 May 23;10(6):642,Fouad.Daayf@umanitoba.ca,"The disruption of ExoPG did not influence virulence, nor did it affect total exopolygalacturonase activity in V. dahliae.",X Zhu 2021,2021,1 gene,Zhu-2021-Role of Exopolygalacturonase-Related,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 18999,PHI:11717,UniProt,A0A2N6NCM2,GenBank,PMB65022,,,JEF-007,swi6,,,,mbp1,UniProt: J4UQC2; GenBank: EJP67532,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,chromatin-associated protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34070348,PubMed,10.3390/jof7060411,J Fungi (Basel). 2021 May 25;7(6):411,yingsh@zju.edu.cn,"BbSwi6 significantly contributed to hyphal growth, asexual sporulation and virulence.",J L Ding 2021,2021,1 gene,Ding-2021-Transcription Activator Swi6 Interac,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19000,PHI:11718,UniProt,Q2G2U6,GenBank,AF136709_1,,,8325-4,yycF,,,,,,,1280,Staphylococcus aureus,,ATCC 29213,osteomyelitis,rodents,10114,Rattus (related: rat),Sprague-Dawley,,,tibia,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34069543,PubMed,10.3390/antibiotics10050603,Antibiotics (Basel). 2021 May 19;10(5):603,zhanghui1437@wchscu.cn,ASyycF inhibited MRSA invasion in a rat tibial infection model.,S Wu 2021,2021,1 gene,Wu-2021-An Antisense yycF RNA Modulates Biofil,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19001,PHI:11719,UniProt,Q2FWE3,GenBank,ABD31387,,,NCTC 8325,ptpB,,,,,,,1280,Staphylococcus aureus,,SA564,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,polymorphonuclear leukocyte,low-molecular-weight protein arginine phosphatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34069497,PubMed,10.3390/ijms22105342,Int J Mol Sci. 2021 May 19;22(10):5342,markus.bischoff@uks.eu,"SA564 ΔptpB mutant cells were additionally ingested faster by polymorphonuclear leukocytes in a whole blood phagocytosis assay, suggesting that PtpB contributes by several ways positively to the ability of S.aureus to evade host innate immunity.",M I Elhawy 2021,2021,1 gene,Elhawy-2021-The Low-Molecular Weight Protein A,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19002,PHI:11720,UniProt,Q9HVY6,GenBank,AE004857_8,,,PAO1,PA4429,,,,,,PHI:11721; PHI:11722,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,probable cytochrome c1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34069209,PubMed,10.3390/microorganisms9051065,Microorganisms. 2021 May 14;9(5):1065,wangsw@nwu.edu.cn,"PA4429-31 deletion reduced the production of the virulence factors, including pyocyanin, rhamnolipids, elastase, and extracellular polysaccharides, and it resulted in a remarkable decrease in pathogenicity.",L Shen 2021,2021,3 genes,Shen-2021-Deletion of the PA4427-PA4431 Operon,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19003,PHI:11721,UniProt,Q9HVY5,GenBank,AE004857_9,,,PAO1,PA4430,,,,,,PHI:11720; PHI:11722,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,cytochrome b,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34069209,PubMed,10.3390/microorganisms9051065,Microorganisms. 2021 May 14;9(5):1065,wangsw@nwu.edu.cn,"PA4429-31 deletion reduced the production of the virulence factors, including pyocyanin, rhamnolipids, elastase, and extracellular polysaccharides, and it resulted in a remarkable decrease in pathogenicity.",L Shen 2021,2021,3 genes,Shen-2021-Deletion of the PA4427-PA4431 Operon,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19004,PHI:11722,UniProt,Q9HVY4,GenBank,AE004857_10,,,PAO1,PA4431,,,,,,PHI:11720; PHI:11721,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,ubiquinol-cytochrome c reductase iron-sulfur subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34069209,PubMed,10.3390/microorganisms9051065,Microorganisms. 2021 May 14;9(5):1065,wangsw@nwu.edu.cn,"PA4429-31 deletion reduced the production of the virulence factors, including pyocyanin, rhamnolipids, elastase, and extracellular polysaccharides, and it resulted in a remarkable decrease in pathogenicity.",L Shen 2021,2021,3 genes,Shen-2021-Deletion of the PA4427-PA4431 Operon,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19005,PHI:11720,UniProt,Q9HVY6,GenBank,AE004857_8,,,PAO1,PA4429,,,,,,PHI:11721; PHI:11722,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),Canton-S,,,,probable cytochrome c1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34069209,PubMed,10.3390/microorganisms9051065,Microorganisms. 2021 May 14;9(5):1065,wangsw@nwu.edu.cn,"PA4429-31 deletion reduced the production of the virulence factors, including pyocyanin, rhamnolipids, elastase, and extracellular polysaccharides, and it resulted in a remarkable decrease in pathogenicity.",L Shen 2021,2021,3 genes,Shen-2021-Deletion of the PA4427-PA4431 Operon,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19006,PHI:11721,UniProt,Q9HVY5,GenBank,AE004857_9,,,PAO1,PA4430,,,,,,PHI:11720; PHI:11722,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),Canton-S,,,,cytochrome b,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34069209,PubMed,10.3390/microorganisms9051065,Microorganisms. 2021 May 14;9(5):1065,wangsw@nwu.edu.cn,"PA4429-31 deletion reduced the production of the virulence factors, including pyocyanin, rhamnolipids, elastase, and extracellular polysaccharides, and it resulted in a remarkable decrease in pathogenicity.",L Shen 2021,2021,3 genes,Shen-2021-Deletion of the PA4427-PA4431 Operon,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19007,PHI:11722,UniProt,Q9HVY4,GenBank,AE004857_10,,,PAO1,PA4431,,,,,,PHI:11720; PHI:11721,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,flies,7227,Drosophila melanogaster (related: fruit fly),Canton-S,,,,ubiquinol-cytochrome c reductase iron-sulfur subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34069209,PubMed,10.3390/microorganisms9051065,Microorganisms. 2021 May 14;9(5):1065,wangsw@nwu.edu.cn,"PA4429-31 deletion reduced the production of the virulence factors, including pyocyanin, rhamnolipids, elastase, and extracellular polysaccharides, and it resulted in a remarkable decrease in pathogenicity.",L Shen 2021,2021,3 genes,Shen-2021-Deletion of the PA4427-PA4431 Operon,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19008,PHI:11723,UniProt,Q93C89,GenBank,AF411587_1,,,SL1344,hilE,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,Hcp-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34048498,PubMed,10.1371/journal.ppat.1009630,PLoS Pathog. 2021 May 28;17(5):e1009630,victor.bustamante@ibt.unam.mx,The absence of HilE attenuated the intestinal colonization by S. Typhimurium in a HilD-dependent way.,D Perez-Morales 2021,2021,1 gene,Pérez-Morales-2021-An incoherent feedforward l,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19009,PHI:11724,UniProt,E1WAC0,GenBank,AAD21081,,,SL1344,hilD,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34048498,PubMed,10.1371/journal.ppat.1009630,PLoS Pathog. 2021 May 28;17(5):e1009630,victor.bustamante@ibt.unam.mx,The absence of HilE attenuated the intestinal colonization by S. Typhimurium in a HilD-dependent way.,D Perez-Morales 2021,2021,1 gene,Pérez-Morales-2021-An incoherent feedforward l,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19010,PHI:11723,UniProt,Q93C89,GenBank,AF411587_1,,,SL1344,hilE,,,,,,PHI:11724,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cecum,Hcp-like protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34048498,PubMed,10.1371/journal.ppat.1009630,PLoS Pathog. 2021 May 28;17(5):e1009630,victor.bustamante@ibt.unam.mx,The absence of HilE attenuated the intestinal colonization by S. Typhimurium in a HilD-dependent way.,D Perez-Morales 2021,2021,1 gene,Pérez-Morales-2021-An incoherent feedforward l,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19011,PHI:11724,UniProt,E1WAC0,GenBank,AAD21081,,,SL1344,hilD,,,,,,PHI:11723,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,cecum,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34048498,PubMed,10.1371/journal.ppat.1009630,PLoS Pathog. 2021 May 28;17(5):e1009630,victor.bustamante@ibt.unam.mx,The absence of HilE attenuated the intestinal colonization by S. Typhimurium in a HilD-dependent way.,D Perez-Morales 2021,2021,1 gene,Pérez-Morales-2021-An incoherent feedforward l,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19012,PHI:11725,,no data found,,,,,,ryfA,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urinary bladder; kidney,small RNA,,,,reduced virulence,,,,,,,,,,no,NaCl; urea; H2O2,NaCl: CHEBI:267101; urea: CHEBI:16199; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34043736,PubMed,10.1371/journal.ppat.1009617,PLoS Pathog. 2021 May 27;17(5):e1009617,charles.dozois@inrs.ca,"Inactivation of ryfA in UPEC strain CFT073 decreased urinary tract colonization in mice and the ryfA mutant also had reduced production of type 1 and P fimbriae (pili), adhesins which are known to be important for UTI.",H Bessaiah 2021,2021,2 genes,Bessaiah-2021-The RyfA small RNA regulates oxi,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19013,PHI:11725,,no data found,,,,,,ryfA,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small RNA,,,,reduced virulence,,,,,,,,,,no,NaCl; urea; H2O2,NaCl: CHEBI:267101; urea: CHEBI:16199; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34043736,PubMed,10.1371/journal.ppat.1009617,PLoS Pathog. 2021 May 27;17(5):e1009617,charles.dozois@inrs.ca,"Inactivation of ryfA in UPEC strain CFT073 decreased urinary tract colonization in mice and the ryfA mutant also had reduced production of type 1 and P fimbriae (pili), adhesins which are known to be important for UTI.",H Bessaiah 2021,2021,2 genes,Bessaiah-2021-The RyfA small RNA regulates oxi,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19014,PHI:11726,,no data found,,,,,,oxyR,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small RNA,,,,reduced virulence,,,,,,,,,,no,NaCl; urea; H2O2,NaCl: CHEBI:267101; urea: CHEBI:16199; H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,34043736,PubMed,10.1371/journal.ppat.1009617,PLoS Pathog. 2021 May 27;17(5):e1009617,charles.dozois@inrs.ca,"Inactivation of ryfA in UPEC strain CFT073 decreased urinary tract colonization in mice and the ryfA mutant also had reduced production of type 1 and P fimbriae (pili), adhesins which are known to be important for UTI.",H Bessaiah 2021,2021,2 genes,Bessaiah-2021-The RyfA small RNA regulates oxi,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19015,PHI:11725,,no data found,,,,,,ryfA,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,small RNA,,,,reduced virulence,,,,,,,,,,no,NaCl; urea; H2O2,NaCl: CHEBI:267101; urea: CHEBI:16199; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34043736,PubMed,10.1371/journal.ppat.1009617,PLoS Pathog. 2021 May 27;17(5):e1009617,charles.dozois@inrs.ca,"Inactivation of ryfA in UPEC strain CFT073 decreased urinary tract colonization in mice and the ryfA mutant also had reduced production of type 1 and P fimbriae (pili), adhesins which are known to be important for UTI.",H Bessaiah 2021,2021,2 genes,Bessaiah-2021-The RyfA small RNA regulates oxi,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19016,PHI:11726,,no data found,,,,,,oxyR,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,small RNA,,,,reduced virulence,,,,,,,,,,no,NaCl; urea; H2O2,NaCl: CHEBI:267101; urea: CHEBI:16199; H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,34043736,PubMed,10.1371/journal.ppat.1009617,PLoS Pathog. 2021 May 27;17(5):e1009617,charles.dozois@inrs.ca,"Inactivation of ryfA in UPEC strain CFT073 decreased urinary tract colonization in mice and the ryfA mutant also had reduced production of type 1 and P fimbriae (pili), adhesins which are known to be important for UTI.",H Bessaiah 2021,2021,2 genes,Bessaiah-2021-The RyfA small RNA regulates oxi,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19017,PHI:11725,,no data found,,,,,,ryfA,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,primates,9606,Homo sapiens (related: human),HMDM cells,,,macrophage,small RNA,,,,reduced virulence,,,,,,,,,,no,NaCl; urea; H2O2,NaCl: CHEBI:267101; urea: CHEBI:16199; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34043736,PubMed,10.1371/journal.ppat.1009617,PLoS Pathog. 2021 May 27;17(5):e1009617,charles.dozois@inrs.ca,"Inactivation of ryfA in UPEC strain CFT073 decreased urinary tract colonization in mice and the ryfA mutant also had reduced production of type 1 and P fimbriae (pili), adhesins which are known to be important for UTI.",H Bessaiah 2021,2021,2 genes,Bessaiah-2021-The RyfA small RNA regulates oxi,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19018,PHI:11726,,no data found,,,,,,oxyR,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,primates,9606,Homo sapiens (related: human),HMDM cells,,,macrophage,small RNA,,,,reduced virulence,,,,,,,,,,no,NaCl; urea; H2O2,NaCl: CHEBI:267101; urea: CHEBI:16199; H2O2: CHEBI:16240,,,,,gene deletion: full,,,YVS,34043736,PubMed,10.1371/journal.ppat.1009617,PLoS Pathog. 2021 May 27;17(5):e1009617,charles.dozois@inrs.ca,"Inactivation of ryfA in UPEC strain CFT073 decreased urinary tract colonization in mice and the ryfA mutant also had reduced production of type 1 and P fimbriae (pili), adhesins which are known to be important for UTI.",H Bessaiah 2021,2021,2 genes,Bessaiah-2021-The RyfA small RNA regulates oxi,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19019,PHI:11727,UniProt,A0A0D6ZUL4,GenBank,API09550,,,319,espO1,,,,,,,562,Escherichia coli,,ICC303,diarrhea; hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,staurosporine; tunicamycin,staurosporine: CHEBI:15738; tunicamycin: CHEBI:29699,,,,,other evidence: ectopic expression,,,YVS,34021690,PubMed,10.1111/cmi.13366,Cell Microbiol. 2021 Sep;23(9):e13366,a.clements@imperial.ac.uk,EspO1 inhibited cell death during infection in a HAX-1-dependent manner.,S Chatterjee 2021,2021,1 gene,Chatterjee-2021-The type III secretion system,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19020,PHI:11728,UniProt,O51510,GenBank,AAC66924,,,B31,bb0562,,,,,,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19021,PHI:11729,UniProt,O51511,GenBank,AAC66940,,,B31,bb0563,,,,,,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19022,PHI:11730,UniProt,O51512,GenBank,AAC66939,,,B31,bb0564,,,,,,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19023,PHI:11728,UniProt,O51510,GenBank,AAC66924,,,B31,bb0562,,,,,,PHI:11729; PHI:11730,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19024,PHI:11729,UniProt,O51511,GenBank,AAC66940,,,B31,bb0563,,,,,,PHI:11728; PHI:11730,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19025,PHI:11730,UniProt,O51512,GenBank,AAC66939,,,B31,bb0564,,,,,,PHI:11728; PHI:11729,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,blood,conserved hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19026,PHI:11730,UniProt,O51510,GenBank,AAC66924,,,B31,bb0562,,,,,,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19027,PHI:11728,UniProt,O51510,GenBank,AAC66924,,,B31,bb0562,,,,,,PHI:11729; PHI:11730,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19028,PHI:11729,UniProt,O51511,GenBank,AAC66940,,,B31,bb0563,,,,,,PHI:11728; PHI:11730,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19029,PHI:11730,UniProt,O51512,GenBank,AAC66939,,,B31,bb0564,,,,,,PHI:11728; PHI:11729,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19030,PHI:11728,UniProt,O51510,GenBank,AAC66924,,,B31,bb0562,,,,,,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19031,PHI:11729,UniProt,O51511,GenBank,AAC66940,,,B31,bb0563,,,,,,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19032,PHI:11730,UniProt,O51512,GenBank,AAC66939,,,B31,bb0564,,,,,,,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19033,PHI:11728,UniProt,O51510,GenBank,AAC66924,,,B31,bb0562,,,,,,PHI:11729; PHI:11730,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19034,PHI:11729,UniProt,O51511,GenBank,AAC66940,,,B31,bb0563,,,,,,PHI:11728; PHI:11730,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19035,PHI:11730,UniProt,O51512,GenBank,AAC66939,,,B31,bb0564,,,,,,PHI:11728; PHI:11729,139,Borreliella burgdorferi,224326,B31 A3,Lyme disease,mites and ticks,6945,Ixodes scapularis (related: black-legged tick),,,,,conserved hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34415955,PubMed,10.1371/journal.ppat.1009869,PLoS Pathog. 2021 Aug 20;17(8):e1009869,Mollie.Jewett@ucf.edu,Genes bb0562-bb0564 were dispensable for B. burgdorferi survival and replication in ticks but bb0562 was important for mouse infection by tick bite transmission.,H W Kuhn 2021,2021,3 genes,Kuhn-2021-BB0562 is a nutritional virulence de,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19036,PHI:11731,UniProt,A0A1C3YIF8,GenBank,SCB64337,,,PH-1,Chs7 (FGSG_12039),chromosome 1,,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,spikelet,chitin synthase 7,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34305830,PubMed,10.3389/fmicb.2021.660976,Front Microbiol. 2021 Jul 9;12:660976,jingbozhang@mail.hzau.edu.cn,"Double-strand RNAs (dsRNAs) of three selected RNAi constructs (Chs7RNAi-4, GlsRNAi-6 and PkcRNA-5) displayed effective silencing effects on mycelium growth in medium and pathogenicity in wheat spikes.",P Yang 2021,2021,3 genes,Yang-2021-Application of Double-Strand RNAs Ta,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19037,PHI:11732,UniProt,I1RUP6,GenBank,CEF85433,,,PH-1,Gls (FGSG_07946),chromosome 4,,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,spikelet,glucan synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34305830,PubMed,10.3389/fmicb.2021.660976,Front Microbiol. 2021 Jul 9;12:660976,jingbozhang@mail.hzau.edu.cn,"Double-strand RNAs (dsRNAs) of three selected RNAi constructs (Chs7RNAi-4, GlsRNAi-6 and PkcRNA-5) displayed effective silencing effects on mycelium growth in medium and pathogenicity in wheat spikes.",P Yang 2021,2021,3 genes,Yang-2021-Application of Double-Strand RNAs Ta,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19038,PHI:11733,,no data found,,,,,,pkc (FGSG_90606),,,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Annong 8455,,,spikelet,protein kinase C,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34305830,PubMed,10.3389/fmicb.2021.660976,Front Microbiol. 2021 Jul 9;12:660976,jingbozhang@mail.hzau.edu.cn,"Double-strand RNAs (dsRNAs) of three selected RNAi constructs (Chs7RNAi-4, GlsRNAi-6 and PkcRNA-5) displayed effective silencing effects on mycelium growth in medium and pathogenicity in wheat spikes.",P Yang 2021,2021,3 genes,Yang-2021-Application of Double-Strand RNAs Ta,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19039,PHI:11731,UniProt,A0A1C3YIF8,GenBank,SCB64337,,,PH-1,Chs7 (FGSG_12039),chromosome 1,,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Fielder,,,leaf,chitin synthase 7,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34305830,PubMed,10.3389/fmicb.2021.660976,Front Microbiol. 2021 Jul 9;12:660976,jingbozhang@mail.hzau.edu.cn,"Double-strand RNAs (dsRNAs) of three selected RNAi constructs (Chs7RNAi-4, GlsRNAi-6 and PkcRNA-5) displayed effective silencing effects on mycelium growth in medium and pathogenicity in wheat spikes.",P Yang 2021,2021,3 genes,Yang-2021-Application of Double-Strand RNAs Ta,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19040,PHI:11732,UniProt,I1RUP6,GenBank,CEF85433,,,PH-1,Gls (FGSG_07946),chromosome 4,,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Fielder,,,leaf,glucan synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34305830,PubMed,10.3389/fmicb.2021.660976,Front Microbiol. 2021 Jul 9;12:660976,jingbozhang@mail.hzau.edu.cn,"Double-strand RNAs (dsRNAs) of three selected RNAi constructs (Chs7RNAi-4, GlsRNAi-6 and PkcRNA-5) displayed effective silencing effects on mycelium growth in medium and pathogenicity in wheat spikes.",P Yang 2021,2021,3 genes,Yang-2021-Application of Double-Strand RNAs Ta,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19041,PHI:11733,,no data found,,,,,,pkc (FGSG_90606),,,,,,,5518,Fusarium graminearum,,5035,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Fielder,,,leaf,protein kinase C,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34305830,PubMed,10.3389/fmicb.2021.660976,Front Microbiol. 2021 Jul 9;12:660976,jingbozhang@mail.hzau.edu.cn,"Double-strand RNAs (dsRNAs) of three selected RNAi constructs (Chs7RNAi-4, GlsRNAi-6 and PkcRNA-5) displayed effective silencing effects on mycelium growth in medium and pathogenicity in wheat spikes.",P Yang 2021,2021,3 genes,Yang-2021-Application of Double-Strand RNAs Ta,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19042,PHI:11734,UniProt,Q4WNS1,GenBank,EAL90113,,,Af293,sepH,chromosome 4,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,serine-threonine kinase,,,,loss of pathogenicity,,,,,,,,reduced,,no,congo red (CR); calcofluor white (CFW); caspofungin; micafungin,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,YVS,34370772,PubMed,10.1371/journal.ppat.1009806,PLoS Pathog. 2021 Aug 9;17(8):e1009806,jfortwen@uthsc.edu,Mutation of each SIN kinase gene also resulted in a profound loss of virulence characterized by lack of tissue invasive growth.,A C O Souza 2021,2021,3 genes,Souza-2021-Loss of Septation Initiation Networ,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19043,PHI:11735,UniProt,B0YDG1,GenBank,EDP47695,,,A1163,AFUB_095460 (sidB),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,"serine/threonine protein kinase, putative",,,,loss of pathogenicity,,,,,,,,reduced,,no,congo red (CR); calcofluor white (CFW); caspofungin; micafungin,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,YVS,34370772,PubMed,10.1371/journal.ppat.1009806,PLoS Pathog. 2021 Aug 9;17(8):e1009806,jfortwen@uthsc.edu,Mutation of each SIN kinase gene also resulted in a profound loss of virulence characterized by lack of tissue invasive growth.,A C O Souza 2021,2021,3 genes,Souza-2021-Loss of Septation Initiation Networ,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19044,PHI:11736,,no data found,,,,,,AFUB_05070 (sepL),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,septation initiation network kinase,,,,loss of pathogenicity,,,,,,,,reduced,,no,congo red (CR); calcofluor white (CFW); caspofungin; micafungin,Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,YVS,34370772,PubMed,10.1371/journal.ppat.1009806,PLoS Pathog. 2021 Aug 9;17(8):e1009806,jfortwen@uthsc.edu,Mutation of each SIN kinase gene also resulted in a profound loss of virulence characterized by lack of tissue invasive growth.,A C O Souza 2021,2021,3 genes,Souza-2021-Loss of Septation Initiation Networ,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19045,PHI:11737,,no data found,GenBank,ACF55534,,,G54,tcs09,,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung; blood,two-component regulatory system 09,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34201716,PubMed,10.3390/microorganisms9071365,Microorganisms. 2021 Jun 23;9(7):1365,sven.hammerschmidt@uni-greifswald.de,In vivo infections demonstrated that TCS09 enhanced robustness during dissemination in the host by maintaining bacterial fitness.,S Hirschmann 2021,2021,1 gene,Hirschmann-2021-The Two-Component System 09 of,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19046,PHI:11737,,no data found,GenBank,ACF55534,,,G54,tcs09,,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,two-component regulatory system 09,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34201716,PubMed,10.3390/microorganisms9071365,Microorganisms. 2021 Jun 23;9(7):1365,sven.hammerschmidt@uni-greifswald.de,Adherence and phagocytosis assays showed no impact of TCS09 on the TIGR4 cell morphology and interaction with host cells.,S Hirschmann 2021,2021,1 gene,Hirschmann-2021-The Two-Component System 09 of,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19047,PHI:11737,,no data found,GenBank,ACF55534,,,G54,tcs09,,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal meningitis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,two-component regulatory system 09,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34201716,PubMed,10.3390/microorganisms9071365,Microorganisms. 2021 Jun 23;9(7):1365,sven.hammerschmidt@uni-greifswald.de,Adherence and phagocytosis assays showed no impact of TCS09 on the TIGR4 cell morphology and interaction with host cells.,S Hirschmann 2021,2021,1 gene,Hirschmann-2021-The Two-Component System 09 of,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19048,PHI:11738,UniProt,E0SH71,GenBank,ADN00164,,,3937,hfq,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,RNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34248909,PubMed,10.3389/fmicb.2021.687484,Front Microbiol. 2021 Jun 24;12:687484,sylvie.reverchon-pescheux@insalyon.fr,The hfq mutant failed to cause soft rot on chicory leaves.,S Leonard 2021,2021,2 genes,Leonard-2021-RNA Chaperones Hfq and ProQ Play,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19049,PHI:11739,UniProt,E0SF07,GenBank,ADM98749,,,3937,proQ,,,,,,,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,RNA chaperone,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34248909,PubMed,10.3389/fmicb.2021.687484,Front Microbiol. 2021 Jun 24;12:687484,sylvie.reverchon-pescheux@insalyon.fr,"The proQ mutant had reduced resistance to osmotic stress, reduced extracellular pectate lyase activity compared to the wild-type strain, and reduced virulence on chicory leaves.",S Leonard 2021,2021,2 genes,Leonard-2021-RNA Chaperones Hfq and ProQ Play,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19050,PHI:11738,UniProt,E0SH71,GenBank,ADN00164,,,3937,hfq,,,,,,PHI:11739,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,RNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34248909,PubMed,10.3389/fmicb.2021.687484,Front Microbiol. 2021 Jun 24;12:687484,sylvie.reverchon-pescheux@insalyon.fr,The hfq mutant failed to cause soft rot on chicory leaves.,S Leonard 2021,2021,2 genes,Leonard-2021-RNA Chaperones Hfq and ProQ Play,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19051,PHI:11739,UniProt,E0SF07,GenBank,ADM98749,,,3937,proQ,,,,,,PHI:11738,204038,Dickeya dadantii,198628,EC3937,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,RNA chaperone,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34248909,PubMed,10.3389/fmicb.2021.687484,Front Microbiol. 2021 Jun 24;12:687484,sylvie.reverchon-pescheux@insalyon.fr,"The proQ mutant had reduced resistance to osmotic stress, reduced extracellular pectate lyase activity compared to the wild-type strain, and reduced virulence on chicory leaves.",S Leonard 2021,2021,2 genes,Leonard-2021-RNA Chaperones Hfq and ProQ Play,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19052,PHI:11740,UniProt,E9AS21,GenBank,XP_003874247,,,MHOM/GT/2001/U1103,FAZ7B (LmxM.19.0690 ),chromosome 19,,,,,,5665,Leishmania mexicana,,Cas9-T7,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bone marrow-derived macrophage,putative kinesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34143858,PubMed,10.1371/journal.ppat.1009666,PLoS Pathog. 2021 Jun 18;17(6):e1009666,patrick.bastien@umontpellier.fr,Loss of the kinesin FAZ7B reduced proliferation in the sand fly and pathogenicity in mice.,R M Corrales 2021,2021,1 gene,Corrales-2021-The kinesin of the flagellum att,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19053,PHI:11740,UniProt,E9AS21,GenBank,XP_003874247,,,MHOM/GT/2001/U1103,FAZ7B (LmxM.19.0690 ),chromosome 19,,,,,,5665,Leishmania mexicana,,Cas9-T7,leishmaniasis,flies,7200,Lutzomyia longipalpis (no common name found),,,,gut,putative kinesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34143858,PubMed,10.1371/journal.ppat.1009666,PLoS Pathog. 2021 Jun 18;17(6):e1009666,patrick.bastien@umontpellier.fr,Loss of the kinesin FAZ7B reduced proliferation in the sand fly and pathogenicity in mice.,R M Corrales 2021,2021,1 gene,Corrales-2021-The kinesin of the flagellum att,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19054,PHI:11741,UniProt,G4MSZ4,GenBank,EHA54653,,,70-15,MoRgs1 (MGG_14517),chromosome 2,,,MoEmc2 (MGG_07480); MoCka1 (MGG_03696); MoCkb1 (MGG_00446); MoCkb2 (MGG_05651),UniProt: G4N1A1; GenBank: EHA51580; UniProt: G4N6P9; GenBank: EHA49866; UniProt: G4NC35; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,developmental regulator,,,,reduced virulence,,yes,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34133468,PubMed,10.1371/journal.ppat.1009657,PLoS Pathog. 2021 Jun 16;17(6):e1009657,zhgzhang@njau.edu.cn,MoRgs1 phosphorylation was required for appressorium formation and pathogenicity.,R Yu 2021,2021,2 genes,Yu-2021-The rice blast fungus MoRgs1 functioni,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19055,PHI:11742,UniProt,G4N1A1,GenBank,EHA51580,,,70-15,MoEmc2 (MGG_07480),chromosome 2,,,MoRgs1 (MGG_14517); MoCka1 (MGG_03696); MoCkb1 (MGG_00446); MoCkb2 (MGG_05651),UniProt: G4MSZ4; GenBank: EHA54653; UniProt: G4N6P9; GenBank: EHA49866; UniProt: G4NC35; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ER membrane protein complex subunit 2,,,,reduced virulence,,yes,yes,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34133468,PubMed,10.1371/journal.ppat.1009657,PLoS Pathog. 2021 Jun 16;17(6):e1009657,zhgzhang@njau.edu.cn,"MoEmc2 was required for the development, differentiation, and full virulence of M. oryzae.",R Yu 2021,2021,2 genes,Yu-2021-The rice blast fungus MoRgs1 functioni,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19056,PHI:11743,UniProt,A0A0H2ZJ53,GenBank,ABJ14625,,,UCBPP-PA14,ppk1 (PA14_69230),,,,,,PHI:11744; PHI:11745; PHI:11746,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,polyphosphate kinase,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin; tetracycline,ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902,,,,,gene deletion: full; gene complementation,,,YVS,34126765,PubMed,10.1128/mBio.00592-21,mBio. 2021 Jun 29;12(3):e0059221,jia@queensu.ca,Gallein-treated and ΔpolyP bacteria exhibited near-WT growth kinetics.,N Neville 2021,2021,4 genes,Neville-2021-A Dual-Specificity Inhibitor Targ,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19057,PHI:11744,UniProt,A0A0H2ZKF2,GenBank,ABJ15097,,,UCBPP-PA14,ppk2A (PA14_01730),,,,,,PHI:11743; PHI:11745; PHI:11746,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,polyphosphate kinase,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin; tetracycline,ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902,,,,,gene deletion: full; gene complementation,,,YVS,34126765,PubMed,10.1128/mBio.00592-21,mBio. 2021 Jun 29;12(3):e0059221,jia@queensu.ca,Gallein-treated and ΔpolyP bacteria exhibited near-WT growth kinetics.,N Neville 2021,2021,4 genes,Neville-2021-A Dual-Specificity Inhibitor Targ,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19058,PHI:11745,UniProt,A0A0H2ZBJ8,GenBank,ABJ11611,,,UCBPP-PA14,ppk2B (PA14_33240),,,,,,PHI:11743; PHI:11744; PHI:11746,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,polyphosphate kinase,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin; tetracycline,ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902,,,,,gene deletion: full; gene complementation,,,YVS,34126765,PubMed,10.1128/mBio.00592-21,mBio. 2021 Jun 29;12(3):e0059221,jia@queensu.ca,Gallein-treated and ΔpolyP bacteria exhibited near-WT growth kinetics.,N Neville 2021,2021,4 genes,Neville-2021-A Dual-Specificity Inhibitor Targ,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19059,PHI:11746,UniProt,A0A0H2ZE52,GenBank,ABJ12711,,,UCBPP-PA14,ppk2C (PA14_19410),,,,,,PHI:11743; PHI:11744; PHI:11745,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,polyphosphate kinase,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin; tetracycline,ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902,,,,,gene deletion: full; gene complementation,,,YVS,34126765,PubMed,10.1128/mBio.00592-21,mBio. 2021 Jun 29;12(3):e0059221,jia@queensu.ca,Gallein-treated and ΔpolyP bacteria exhibited near-WT growth kinetics.,N Neville 2021,2021,4 genes,Neville-2021-A Dual-Specificity Inhibitor Targ,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19060,PHI:11743,UniProt,A0A0H2ZJ53,GenBank,ABJ14625,,,UCBPP-PA14,ppk1 (PA14_69230),,,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,polyphosphate kinase,,,,reduced virulence,,,,,,,,,,no,ciprofloxacin; tetracycline,ciprofloxacin: CHEBI:100241; tetracycline: CHEBI:27902,,,,,gene deletion: full; gene complementation,,,YVS,34126765,PubMed,10.1128/mBio.00592-21,mBio. 2021 Jun 29;12(3):e0059221,jia@queensu.ca,Gallein-treated and ΔpolyP bacteria exhibited near-WT growth kinetics.,N Neville 2021,2021,4 genes,Neville-2021-A Dual-Specificity Inhibitor Targ,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19061,PHI:11747,UniProt,O25531,GenBank,AAD07906,,,26695,HP0860 (GmhB),,,,,,,210,Helicobacter pylori,85962,26695,chronic gastritis,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,"D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase",,,ADP-heptose biosynthesis,reduced virulence,,,,,,,,,,no,novobiocin,novobiocin: CHEBI:28368,,,,,gene deletion: full; gene complementation,,,YVS,34125649,PubMed,10.1080/21505594.2021.1938449,Virulence. 2021 Dec;12(1):1610-1628,mckao@life.nthu.edu.tw,"HP0860 knockout mutant was much more sensitive to antibiotic novobiocin, had decreased adherence abilities, and caused less classic hummingbird phenotype on the infected AGS cells, indicating H. pylori lacking HP0860 is less virulent.",S F Chiu 2021,2021,1 gene,Chiu-2021-Helicobacter pylori GmhB enzyme invo,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19062,PHI:11748,UniProt,P23484,GenBank,AAA23766,,,K-12,fecI,,,,,,PHI:11749; PHI:11750; PHI:11751; PHI:11752; PHI:11753; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; heart; liver; spleen; kidney; lung,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19063,PHI:11749,UniProt,P23485,GenBank,AAA23767,,,K-12,fecR,,,,,,PHI:11748; PHI:11750; PHI:11751; PHI:11752; PHI:11753; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; heart; liver; spleen; kidney; lung,Fec operon regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19064,PHI:11750,UniProt,P13036,GenBank,AAC77247,,,K-12,fecA,,,,,,PHI:11748; PHI:11749; PHI:11751; PHI:11752; PHI:11753; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; heart; liver; spleen; kidney; lung,Fe(3+) dicitrate transport protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19065,PHI:11751,UniProt,P15028,GenBank,AAA23762,,,K-12,fecB,,,,,,PHI:11748; PHI:11749; PHI:11750; PHI:11752; PHI:11753; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; heart; liver; spleen; kidney; lung,Fe(3+) dicitrate-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19066,PHI:11752,UniProt,P15030,GenBank,AAA23763,,,K-12,fecC,,,,,,PHI:11748; PHI:11749; PHI:11750; PHI:11751; PHI:11753; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; heart; liver; spleen; kidney; lung,Fe(3+) dicitrate transport system permease protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19067,PHI:11753,UniProt,P15029,GenBank,AAA23764,,,K-12,fecD,,,,,,PHI:11748; PHI:11749; PHI:11750; PHI:11751; PHI:11752; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; heart; liver; spleen; kidney; lung,Fe(3+) dicitrate transport system permease protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19068,PHI:11754,UniProt,P15031,GenBank,AAA23765,,,K-12,fecE,,,,,,PHI:11748; PHI:11749; PHI:11750; PHI:11751; PHI:11752; PHI:11753,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; heart; liver; spleen; kidney; lung,Fe(3+) dicitrate transport ATP-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19069,PHI:11748,UniProt,P23484,GenBank,AAA23766,,,K-12,fecI,,,,,,PHI:11749; PHI:11750; PHI:11751; PHI:11752; PHI:11753; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney,ferric citrate uptake (fec) system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19070,PHI:11749,UniProt,P23485,GenBank,AAA23767,,,K-12,fecR,,,,,,PHI:11748; PHI:11750; PHI:11751; PHI:11752; PHI:11753; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney,ferric citrate uptake (fec) system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19071,PHI:11750,UniProt,P13036,GenBank,AAC77247,,,K-12,fecA,,,,,,PHI:11748; PHI:11749; PHI:11751; PHI:11752; PHI:11753; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney,ferric citrate uptake (fec) system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19072,PHI:11751,UniProt,P15028,GenBank,AAA23762,,,K-12,fecB,,,,,,PHI:11748; PHI:11749; PHI:11750; PHI:11752; PHI:11753; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney,ferric citrate uptake (fec) system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19073,PHI:11752,UniProt,P15030,GenBank,AAA23763,,,K-12,fecC,,,,,,PHI:11748; PHI:11749; PHI:11750; PHI:11751; PHI:11753; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney,ferric citrate uptake (fec) system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19074,PHI:11753,UniProt,P15029,GenBank,AAA23764,,,K-12,fecD,,,,,,PHI:11748; PHI:11749; PHI:11750; PHI:11751; PHI:11752; PHI:11754,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney,ferric citrate uptake (fec) system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19075,PHI:11754,UniProt,P15031,GenBank,AAA23765,,,K-12,fecE,,,,,,PHI:11748; PHI:11749; PHI:11750; PHI:11751; PHI:11752; PHI:11753,562,Escherichia coli,,EC41,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney,ferric citrate uptake (fec) system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34122381,PubMed,10.3389/fmicb.2021.667782,Front Microbiol. 2021 May 26;12:667782,chteng@mail.ncku.edu.tw,The fec system contributed to the pathogenesis of EC41 in systemic infections but not in urinary tract infections (UTIs).,W C Huang 2021,2021,7 genes,Huang-2021-The Ferric Citrate Uptake System En,BATCH_108C,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19076,PHI:11755,UniProt,Q7A656,GenBank,BAB42225,,,N315,isdb,,,,,,,1280,Staphylococcus aureus,,SH1000,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),HUVECs,,,HUVEC cell,iron-regulated surface determinant protein B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34815454,PubMed,10.1038/s41598-021-02065-w,Sci Rep. 2021 Nov 23;11(1):22799,giampiero.pietrocola@unipv.it,"A significantly higher attachment of the WT strain compared to the isdB mutant was observed, indicating the important role of IsdB in bacterial adhesion to von Willebrand factor.",M J Alfeo 2021,2021,1 gene,Alfeo-2021-Staphylococcus aureus iron-regulate,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19077,PHI:11756,,no data found,GenBank,CFQ92061,,,DE-NI-014,ess (S protein),,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen; brain; blood,S protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34721327,PubMed,10.3389/fmicb.2021.729308,Front Microbiol. 2021 Oct 14;12:729308,djgonzalez@health.ucsd.edu,S protein deletion sensitizes Group B Streptococcus to killing invitro and invivo.,A Campeau 2021,2021,1 gene,Campeau-2021-The S Protein of Group B Streptoc,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19078,PHI:11756,,no data found,GenBank,CFQ92061,,,DE-NI-014,ess (S protein),,,,,,,1311,Streptococcus agalactiae,1427374,group B serotype V strain CNCTC 10/84,group B streptococcal infection,primates,9606,Homo sapiens (related: human),,,,blood,S protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34721327,PubMed,10.3389/fmicb.2021.729308,Front Microbiol. 2021 Oct 14;12:729308,djgonzalez@health.ucsd.edu,S protein deletion sensitizes Group B Streptococcus to killing invitro and invivo.,A Campeau 2021,2021,1 gene,Campeau-2021-The S Protein of Group B Streptoc,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19079,PHI:11757,UniProt,K9G133,GenBank,EKV06966,,,Pd1,PdMut3 (PDIP_75320),,,,,,,36651,Penicillium digitatum,1170230,Pd1,green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Navel,,,fruit,putative Zn (II) 2Cys6 DNA-binding protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,FeCl3; SDS; tween 20; methanol; Congo red; calcofluor white; EDTA; H2O2,"FeCl3: CHEBI:30808; SDS: CHEBI:8984, 20; tween: CHEBI:53424; methanol: CHEBI:17790; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; EDTA: CHEBI:64758; H2O2: CHEBI:16240",,,,,gene deletion: full,,,YVS,34682249,PubMed,10.3390/jof7100828,J Fungi (Basel). 2021 Oct 3;7(10):828,psanchez@iata.csic.es,Elimination of PdMut3 in Pd1 strain caused increased virulence during citrus infection.,M de Ramón-Carbon 2021,2021,1 gene,de Ramón-Carbon-2021-Unveiling the Role Displa,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19080,PHI:11758,UniProt,W7LLV0,GenBank,EWG36475,,,7600,FvCpsA (FVEG_00488),chromosome 1,,,,,,117187,Fusarium verticillioides,,,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,kernel,glycosyltransferase,,,,reduced virulence,,yes,yes,,,,,reduced; aberrant,,no,NaCl; Congo red,NaCl: CHEBI:267101; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34679011,PubMed,10.3390/toxins13100718,Toxins (Basel). 2021 Oct 11;13(10):718,wendeliu@126.com,"The deletion of FvCPSA showed penetration defects on cellophane membrane, and thus led to obvious defects in pathogenicity.",Q Deng 2021,2021,1 gene,Deng-2021-Glycosyltransferase FvCpsA Regulates,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19081,PHI:11759,UniProt,C3T032,GenBank,ACI80066,,,493/89,ppk1,,,,,,,562,Escherichia coli,155864,EDL933w,colitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,colon,polyphosphate kinase 1,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34777317,PubMed,10.3389/fmicb.2021.762171,Front Microbiol. 2021 Oct 27;12:762171,gzwcs@smu.edu.cn,"The deletion of the ppk1 gene reduced the adhesion, formation of attaching and effacing (A/E) lesions, and invasive ability of EHEC O157:H7.",Y Du 2021,2021,1 gene,Du-2021-Polyphosphate Kinase 1 Is a Pathogenes,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19082,PHI:11759,UniProt,C3T032,GenBank,ACI80066,,,493/89,ppk1,,,,,,,562,Escherichia coli,155864,EDL933w,colitis,primates,9606,Homo sapiens (related: human),LoVo cell line,,,LoVo cell,polyphosphate kinase 1,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34777317,PubMed,10.3389/fmicb.2021.762171,Front Microbiol. 2021 Oct 27;12:762171,gzwcs@smu.edu.cn,The Δppk1 strain was less pathogenic in BALB/c mice.,Y Du 2021,2021,1 gene,Du-2021-Polyphosphate Kinase 1 Is a Pathogenes,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19083,PHI:11760,UniProt,Q5ANA8,GenBank,AOW28534,,,SC5314,MCA1,,,,,,,5476,Candida albicans,,PFCC 9362,vaginal candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,vagina,Ca(2+)-dependent cysteine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: in vitro suppression of gene expression by exposure of Candida albicans cells to cold atmospheric plasma (CAP),,,YVS,34694384,PubMed,10.1093/mmy/myab067,Med Mycol. 2021 Oct 25:myab067. doi: 10.1093/mmy/myab067. Online ahead of print.,mrab442@pasteur.ac.ir,Suppression of CaMCA1 gene reduced fungal pathogenicity in murine model of VVC.,F Ebrahimi-Shaghaghi 2021,,1 gene,Ebrahimi-Shagha-2021-Plasma-based strategy for,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19084,PHI:11761,UniProt,A7F1J8,GenBank,EDN95590,,,1980,SS1G_11468 (SsERP1),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),J9712 line,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34682246,PubMed,10.3390/jof7100825,J Fungi (Basel). 2021 Oct 1;7(10):825,wangyp@yzu.edu.cn,"Ectopic overexpression of SsERP1 in plant leaves promoted Sclerotinia sclerotiorum infection, and the knockout mutants of SsERP1 showed reduced pathogenicity but retained normal mycelial growth and sclerotium formation.",H Fan 2021,2021,1 gene,Fan-2021-A Novel Effector Protein SsERP1 Inhib,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19085,PHI:11761,UniProt,A7F1J8,GenBank,EDN95590,,,1980,SS1G_11468 (SsERP1),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34682246,PubMed,10.3390/jof7100825,J Fungi (Basel). 2021 Oct 1;7(10):825,wangyp@yzu.edu.cn,"Ectopic overexpression of SsERP1 in plant leaves promoted Sclerotinia sclerotiorum infection, and the knockout mutants of SsERP1 showed reduced pathogenicity but retained normal mycelial growth and sclerotium formation.",H Fan 2021,2021,1 gene,Fan-2021-A Novel Effector Protein SsERP1 Inhib,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19086,PHI:11761,UniProt,A7F1J8,GenBank,EDN95590,,,1980,SS1G_11468 (SsERP1),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,other evidence: ectopic overexpression,,,YVS,34682246,PubMed,10.3390/jof7100825,J Fungi (Basel). 2021 Oct 1;7(10):825,wangyp@yzu.edu.cn,"Ectopic overexpression of SsERP1 in plant leaves promoted Sclerotinia sclerotiorum infection, and the knockout mutants of SsERP1 showed reduced pathogenicity but retained normal mycelial growth and sclerotium formation.",H Fan 2021,2021,1 gene,Fan-2021-A Novel Effector Protein SsERP1 Inhib,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19087,PHI:11761,UniProt,A7F1J8,GenBank,EDN95590,,,1980,SS1G_11468 (SsERP1),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34682246,PubMed,10.3390/jof7100825,J Fungi (Basel). 2021 Oct 1;7(10):825,wangyp@yzu.edu.cn,"Ectopic overexpression of SsERP1 in plant leaves promoted Sclerotinia sclerotiorum infection, and the knockout mutants of SsERP1 showed reduced pathogenicity but retained normal mycelial growth and sclerotium formation.",H Fan 2021,2021,1 gene,Fan-2021-A Novel Effector Protein SsERP1 Inhib,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19088,PHI:11762,,no data found,,,,,,nrps1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,non-ribosomal peptide synthetase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,"1,3-diaminopropane (1,3-DAP); spermidine (SPD);spermine (SPM); H2O2; pyrimethanil","1,3-diaminopropane (1,3-DAP): CHEBI:15725; spermidine (SPD): CHEBI:16610; spermine (SPM): CHEBI:15746; H2O2: CHEBI:16240; pyrimethanil: CHEBI:8674",,,,,gene deletion: full,,,YVS,34575759,PubMed,10.3390/jof7090721,J Fungi (Basel). 2021 Sep 3;7(9):721,jesusmanuel.cantoral@uca.es,"Gene deletion reduced the tolerance of B. cinerea B05.10 to toxic substances such as the polyamine SPD and the fungicide pyrimethanil, and its virulence increased.",A Fernández-Moral 2021,2021,1 gene,Fernández-Moral-2021-Deletion of the Bcnrps1 G,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19089,PHI:11762,,no data found,,,,,,nrps1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,non-ribosomal peptide synthetase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,"1,3-diaminopropane (1,3-DAP); spermidine (SPD);spermine (SPM); H2O2; pyrimethanil","1,3-diaminopropane (1,3-DAP): CHEBI:15725; spermidine (SPD): CHEBI:16610; spermine (SPM): CHEBI:15746; H2O2: CHEBI:16240; pyrimethanil: CHEBI:8674",,,,,gene deletion: full,,,YVS,34575759,PubMed,10.3390/jof7090721,J Fungi (Basel). 2021 Sep 3;7(9):721,jesusmanuel.cantoral@uca.es,"Gene deletion reduced the tolerance of B. cinerea B05.10 to toxic substances such as the polyamine SPD and the fungicide pyrimethanil, and its virulence increased.",A Fernández-Moral 2021,2021,1 gene,Fernández-Moral-2021-Deletion of the Bcnrps1 G,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19090,PHI:11763,UniProt,J9R4P0,GenBank,AFR35433,,,RA-CH-1,B739_0832 (OmpH),,,,,,,34085,Riemerella anatipestifer,1228997,RA-CH-1,septicemia,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,blood; liver; brain; spleen; heart,putative outer membrane protein H,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34616377,PubMed,10.3389/fmicb.2021.708225,Front Microbiol. 2021 Sep 20;12:708225,chenganchun@vip.163.com,"Bacterial loads in blood, liver, and brain tissues from ΔB739_0832-infected ducklings were considerably lower than those from wild-type infected ducklings.",Q Gao 2021,2021,1 gene,Gao-2021-Putative Riemerella anatipestifer Out,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19091,PHI:11763,UniProt,J9R4P0,GenBank,AFR35433,,,RA-CH-1,B739_0832 (OmpH),,,,,,,34085,Riemerella anatipestifer,1228997,RA-CH-1,septicemia,birds,8839,Anas platyrhynchos (related: mallard),DEF cells,,,embryo fibroblast cell line,putative outer membrane protein H,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34616377,PubMed,10.3389/fmicb.2021.708225,Front Microbiol. 2021 Sep 20;12:708225,chenganchun@vip.163.com,Deletion of B739_0832 gene decreased Riemerella anatipestifer adhesion and invasion in duck embryo fibroblast cells.,Q Gao 2021,2021,1 gene,Gao-2021-Putative Riemerella anatipestifer Out,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19092,PHI:11764,UniProt,Q6D9Y2,GenBank,CAG73396,,,SCRI1043,entA,,,,,,,29471,Pectobacterium atrosepticum,218491,SCRI1043,soft rot (potato); blackleg disease (potato),eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana SR1,,,leaf,"enterobactin synthetase component A (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)",,,,unaffected pathogenicity,,,,,,,,wild type,,no,Na-EDTA; H2O2; CuSO4,Na-EDTA: CHEBI:64734; H2O2: CHEBI:16240; CuSO4: CHEBI:23414,,,,,gene deletion: full; gene complementation,,,YVS,34502502,PubMed,10.3390/ijms22179594,Int J Mol Sci. 2021 Sep 4;22(17):9594,vladimir.gorshkov@kibb.knc.ru,The entA knockout did not reduce Pba virulence on non-primed plants.,V Gorshkov 2021,2021,1 gene,Gorshkov-2021-The Knockout of Enterobactin-Rel,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19093,PHI:11765,UniProt,Q4WYP6,GenBank,EAL92207,,,Af293,spfA (Afu3g13790),chromosome 6,,,,,,746128,Aspergillus fumigatus,,ku80,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,"P5-type cation transporting ATPase, putative",,,,unaffected pathogenicity,,,,,,,,,,no,"calcofluor white; sorbitol; caspofungin; Congo red; DTT; hygromycin B; tunicamycin; amphotericin B; carvacrol; N-acetyl-L-cysteine; EGTA; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid; menadione (MD); paraquat (PQ); diamide","calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; DTT: CHEBI:42170; hygromycin B: CHEBI:16976; tunicamycin: CHEBI:29699; amphotericin B: CHEBI:2682; carvacrol: CHEBI:3440; N-acetyl-L-cysteine: CHEBI:28939; EGTA: CAS:67-42-5; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid: CHEBI:60888; menadione (MD): CHEBI:28869; paraquat (PQ): CHEBI:34905; diamide: CHEBI:48958",,,,,gene deletion: full; gene complementation,,,YVS,34663092,PubMed,10.1128/mBio.02735-21,mBio. 2021 Oct 26;12(5):e0273521,david.askew@uc.edu,The combined loss of spfA and srcA exacerbated these phenotypes and attenuated virulence in two animal infection models.,J P Guirao-Abad 2021,2021,2 genes,Guirao-Abad-2021-Pleiotropic Effects of the P5,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19094,PHI:11765,UniProt,Q4WYP6,GenBank,EAL92207,,,Af293,spfA (Afu3g13790),chromosome 3,,,,,PHI:11766,746128,Aspergillus fumigatus,,ku80,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,"P5-type cation transporting ATPase, putative",,,,reduced virulence,,,,,,,,,,no,"calcofluor white; sorbitol; caspofungin; Congo red; DTT; hygromycin B; tunicamycin; amphotericin B; carvacrol; N-acetyl-L-cysteine; EGTA; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid; menadione (MD); paraquat (PQ); diamide","calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; DTT: CHEBI:42170; hygromycin B: CHEBI:16976; tunicamycin: CHEBI:29699; amphotericin B: CHEBI:2682; carvacrol: CHEBI:3440; N-acetyl-L-cysteine: CHEBI:28939; EGTA: CAS:67-42-5; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid: CHEBI:60888; menadione (MD): CHEBI:28869; paraquat (PQ): CHEBI:34905; diamide: CHEBI:48958",,,,,gene deletion: full; gene complementation,,,YVS,34663092,PubMed,10.1128/mBio.02735-21,mBio. 2021 Oct 26;12(5):e0273521,david.askew@uc.edu,The combined loss of spfA and srcA exacerbated these phenotypes and attenuated virulence in two animal infection models.,J P Guirao-Abad 2021,2021,2 genes,Guirao-Abad-2021-Pleiotropic Effects of the P5,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19095,PHI:11766,UniProt,Q4WND5,GenBank,EAL88529,,,Af293,srcA (Afu6g06740),chromosome 6,,,,,PHI:11765,746128,Aspergillus fumigatus,,ku80,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CF1,,,lung,"endoplasmic reticulum calcium ATPase, putative",,,,reduced virulence,,,,,,,,,,no,"calcofluor white; sorbitol; caspofungin; Congo red; DTT; hygromycin B; tunicamycin; amphotericin B; carvacrol; N-acetyl-L-cysteine; EGTA; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid; menadione (MD); paraquat (PQ); diamide","calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; DTT: CHEBI:42170; hygromycin B: CHEBI:16976; tunicamycin: CHEBI:29699; amphotericin B: CHEBI:2682; carvacrol: CHEBI:3440; N-acetyl-L-cysteine: CHEBI:28939; EGTA: CAS:67-42-5; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid: CHEBI:60888; menadione (MD): CHEBI:28869; paraquat (PQ): CHEBI:34905; diamide: CHEBI:48958",,,,,gene deletion: full; gene complementation,,,YVS,34663092,PubMed,10.1128/mBio.02735-21,mBio. 2021 Oct 26;12(5):e0273521,david.askew@uc.edu,The combined loss of spfA and srcA exacerbated these phenotypes and attenuated virulence in two animal infection models.,J P Guirao-Abad 2021,2021,2 genes,Guirao-Abad-2021-Pleiotropic Effects of the P5,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19096,PHI:11765,UniProt,Q4WYP6,GenBank,EAL92207,,,Af293,spfA (Afu3g13790),chromosome 6,,,,,,746128,Aspergillus fumigatus,,ku80,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"P5-type cation transporting ATPase, putative",,,,unaffected pathogenicity,,,,,,,,,,no,"calcofluor white; sorbitol; caspofungin; Congo red; DTT; hygromycin B; tunicamycin; amphotericin B; carvacrol; N-acetyl-L-cysteine; EGTA; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid; menadione (MD); paraquat (PQ); diamide","calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; DTT: CHEBI:42170; hygromycin B: CHEBI:16976; tunicamycin: CHEBI:29699; amphotericin B: CHEBI:2682; carvacrol: CHEBI:3440; N-acetyl-L-cysteine: CHEBI:28939; EGTA: CAS:67-42-5; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid: CHEBI:60888; menadione (MD): CHEBI:28869; paraquat (PQ): CHEBI:34905; diamide: CHEBI:48958",,,,,gene deletion: full; gene complementation,,,YVS,34663092,PubMed,10.1128/mBio.02735-21,mBio. 2021 Oct 26;12(5):e0273521,david.askew@uc.edu,The combined loss of spfA and srcA exacerbated these phenotypes and attenuated virulence in two animal infection models.,J P Guirao-Abad 2021,2021,2 genes,Guirao-Abad-2021-Pleiotropic Effects of the P5,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19097,PHI:11765,UniProt,Q4WYP6,GenBank,EAL92207,,,Af293,spfA (Afu3g13790),chromosome 3,,,,,PHI:11766,746128,Aspergillus fumigatus,,ku80,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"P5-type cation transporting ATPase, putative",,,,reduced virulence,,,,,,,,,,no,"calcofluor white; sorbitol; caspofungin; Congo red; DTT; hygromycin B; tunicamycin; amphotericin B; carvacrol; N-acetyl-L-cysteine; EGTA; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid; menadione (MD); paraquat (PQ); diamide","calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; DTT: CHEBI:42170; hygromycin B: CHEBI:16976; tunicamycin: CHEBI:29699; amphotericin B: CHEBI:2682; carvacrol: CHEBI:3440; N-acetyl-L-cysteine: CHEBI:28939; EGTA: CAS:67-42-5; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid: CHEBI:60888; menadione (MD): CHEBI:28869; paraquat (PQ): CHEBI:34905; diamide: CHEBI:48958",,,,,gene deletion: full; gene complementation,,,YVS,34663092,PubMed,10.1128/mBio.02735-21,mBio. 2021 Oct 26;12(5):e0273521,david.askew@uc.edu,The combined loss of spfA and srcA exacerbated these phenotypes and attenuated virulence in two animal infection models.,J P Guirao-Abad 2021,2021,2 genes,Guirao-Abad-2021-Pleiotropic Effects of the P5,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19098,PHI:11766,UniProt,Q4WND5,GenBank,EAL88529,,,Af293,srcA (Afu6g06740),chromosome 6,,,,,PHI:11765,746128,Aspergillus fumigatus,,ku80,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"endoplasmic reticulum calcium ATPase, putative",,,,reduced virulence,,,,,,,,,,no,"calcofluor white; sorbitol; caspofungin; Congo red; DTT; hygromycin B; tunicamycin; amphotericin B; carvacrol; N-acetyl-L-cysteine; EGTA; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid; menadione (MD); paraquat (PQ); diamide","calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911; caspofungin: CHEBI:474180; Congo red: CHEBI:34653; DTT: CHEBI:42170; hygromycin B: CHEBI:16976; tunicamycin: CHEBI:29699; amphotericin B: CHEBI:2682; carvacrol: CHEBI:3440; N-acetyl-L-cysteine: CHEBI:28939; EGTA: CAS:67-42-5; BAPTA [1,2-bis(2-aminophenoxy)ethane-N,N,N9,N9-tetraaceticacid: CHEBI:60888; menadione (MD): CHEBI:28869; paraquat (PQ): CHEBI:34905; diamide: CHEBI:48958",,,,,gene deletion: full; gene complementation,,,YVS,34663092,PubMed,10.1128/mBio.02735-21,mBio. 2021 Oct 26;12(5):e0273521,david.askew@uc.edu,The combined loss of spfA and srcA exacerbated these phenotypes and attenuated virulence in two animal infection models.,J P Guirao-Abad 2021,2021,2 genes,Guirao-Abad-2021-Pleiotropic Effects of the P5,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19099,PHI:11767,UniProt,Q47445,GenBank,AUZ15689,,,13P477T,papG,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,fimbrial adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34493749,PubMed,10.1038/s41598-021-97224-4,Sci Rep. 2021 Sep 7;11(1):17801,manisha.dhanda@gmail.com,PapG deficient UPEC had reduced virulence as shown by significantly increased survival of Caenorhabditis elegans (C. elegans) worms compared to UPEC.,S Gupta 2021,2021,1 gene,Gupta-2021-Targeting of Uropathogenic Escheric,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19100,PHI:11767,UniProt,Q47445,GenBank,AUZ15689,,,13P477T,papG,,,,,,,562,Escherichia coli,199310,CFT073,urinary tract infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,fimbrial adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34493749,PubMed,10.1038/s41598-021-97224-4,Sci Rep. 2021 Sep 7;11(1):17801,manisha.dhanda@gmail.com,PapG deficient UPEC had reduced virulence as shown by significantly increased survival of Caenorhabditis elegans (C. elegans) worms compared to UPEC.,S Gupta 2021,2021,1 gene,Gupta-2021-Targeting of Uropathogenic Escheric,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19101,PHI:11768,UniProt,J9VKM5,GenBank,AFR94798,,,H99,Dnj1 (CNAG_01347),chromosome 5,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; blood; liver; spleen; kidney,endoplasmic reticulum (ER) J-domain containing co-chaperone,,,,reduced virulence,,,,,,,,,,no,tunicamycin; DTT; miconazole (MCZ); fluconazole (FLZ); sorbitol: CHEBI:30911; NaCl; caffeine,tunicamycin: CHEBI:29699; DTT: CHEBI:42170; miconazole (MCZ): CHEBI:6923; fluconazole (FLZ): CHEBI:46081; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; caffeine: CHEBI:27732,,,,,gene deletion: full; gene complementation,,,YVS,34566931,PubMed,10.3389/fmicb.2021.727039,Front Microbiol. 2021 Sep 10;12:727039,kronstad@msl.ubc.ca,Dnj1 was crucial for survival and virulence factor production at elevated temperatures.,L C Horianopoulos 2021,2021,1 gene,Horianopoulos-2021-Dnj1 Promotes Virulence in,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19102,PHI:11768,UniProt,J9VKM5,GenBank,AFR94798,,,H99,Dnj1 (CNAG_01347),chromosome 5,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,endoplasmic reticulum (ER) J-domain containing co-chaperone,,,,reduced virulence,,,,,,,,,,no,tunicamycin; DTT; miconazole (MCZ); fluconazole (FLZ); sorbitol: CHEBI:30911; NaCl; caffeine,tunicamycin: CHEBI:29699; DTT: CHEBI:42170; miconazole (MCZ): CHEBI:6923; fluconazole (FLZ): CHEBI:46081; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; caffeine: CHEBI:27732,,,,,gene deletion: full; gene complementation,,,YVS,34566931,PubMed,10.3389/fmicb.2021.727039,Front Microbiol. 2021 Sep 10;12:727039,kronstad@msl.ubc.ca,The dnj1Δ mutant had decreased uptake by J774.A1 murine macrophages compared to the wild type.,L C Horianopoulos 2021,2021,1 gene,Horianopoulos-2021-Dnj1 Promotes Virulence in,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19103,PHI:11769,UniProt,B7I9N8,GenBank,ACJ40246,,,AB0057,csrA,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,urine,translational regulator,,,,reduced virulence,,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,34730379,PubMed,10.1128/Spectrum.01296-21,Microbiol Spectr. 2021 Nov 3;9(3):e0129621,averhoff@bio.uni-frankfurt.de,CsrA was essential for growth in human urine and at high temperatures.,J J Hubloher 2021,2021,1 gene,Hubloher-2021-CsrA Coordinates Compatible Solu,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19104,PHI:11770,,no data found,GenBank,ABO12301,,,ATCC 17978,leuO (A1S_1874),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,LysR-type transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34708004,PubMed,10.3389/fcimb.2021.738706,Front Cell Infect Microbiol. 2021 Oct 11;11:738706,shinms@knu.ac.kr,Disruption of LeuO led to increased biofilm formation and increased pathogenicity in an animal model.,M M Islam 2021,2021,1 gene,"Islam-2021-LeuO, a LysR-Type Transcriptional R",BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19105,PHI:11770,,no data found,GenBank,ABO12301,,,ATCC 17978,leuO (A1S_1874),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,LysR-type transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34708004,PubMed,10.3389/fcimb.2021.738706,Front Cell Infect Microbiol. 2021 Oct 11;11:738706,shinms@knu.ac.kr,Adherence and surface motility of the LeuO mutant were reduced compared with those of the wild-type strain.,M M Islam 2021,2021,1 gene,"Islam-2021-LeuO, a LysR-Type Transcriptional R",BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19106,PHI:11771,UniProt,Q5ABG1,GenBank,AOW25793,,,SC5314,set1,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,H3 lysine 4 (H3K4) methyltransferase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34696687,PubMed,10.1080/21505594.2021.1980988,Virulence. 2021 Dec;12(1):2648-2658,jungshinlee@kangwon.ac.kr,"Set1 deletion increased H2O2 sensitivity and prevented proper colony formation when interacting with macrophage in vitro, consistent with its attenuated virulence in vivo.",J Kim 2021,2021,1 gene,Kim-2021-Set1-mediated H3K4 methylation is req,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19107,PHI:11771,UniProt,Q5ABG1,GenBank,AOW25793,,,SC5314,set1,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; spleen; liver,H3 lysine 4 (H3K4) methyltransferase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34696687,PubMed,10.1080/21505594.2021.1980988,Virulence. 2021 Dec;12(1):2648-2658,jungshinlee@kangwon.ac.kr,"Set1 deletion increased H2O2 sensitivity and prevented proper colony formation when interacting with macrophage in vitro, consistent with its attenuated virulence in vivo.",J Kim 2021,2021,1 gene,Kim-2021-Set1-mediated H3K4 methylation is req,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19108,PHI:11772,UniProt,V5VHC0,GenBank,AKA33312,,,AB5075-UW,dksA (AlS_0248 ),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,RNA polymerase-binding transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34696704,PubMed,10.1080/21505594.2021.1995253,Virulence. 2021 Dec;12(1):2750-2763,leejc@knu.ac.kr,The ΔdksA mutant strain showed less bacterial burden and milder histopathological changes in the lungs of mice than the WT strain.,N Kim 2021,2021,1 gene,Kim-2021-Global regulator DksA modulates virul,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19109,PHI:11772,UniProt,V5VHC0,GenBank,AKA33312,,,AB5075-UW,dksA (AlS_0248 ),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,RNA polymerase-binding transcription factor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34696704,PubMed,10.1080/21505594.2021.1995253,Virulence. 2021 Dec;12(1):2750-2763,leejc@knu.ac.kr,The ΔdksA mutant strain showed less bacterial burden and milder histopathological changes in the lungs of mice than the WT strain.,N Kim 2021,2021,1 gene,Kim-2021-Global regulator DksA modulates virul,BATCH_109A,2021-11-01,MC,,,,,,,,,,,,,
,,Record 19110,PHI:11773,UniProt,G2X9I0,GenBank,EGY15648,,,VdLs.17,noxA (VDAG_06812),chromosome 8,,,,,,27337,Verticillium dahliae,,Vd1396-9,vascular wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. Kennebec,,,leaf; stem,NADPH oxidase A,,,,reduced virulence,,,yes,,,wild type,,wild type,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,34682235,PubMed,10.3390/jof7100814,J Fungi (Basel). 2021 Sep 28;7(10):814,Fouad.Daayf@umanitoba.ca,NoxA mutants had significantly reduced virulence and reduced cellophane penetration ability compared to the wild type.,X Zhu 2021,2021,1 gene,Zhu-2021-NOXA Is Important for Verticillium da,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19111,PHI:11774,UniProt,Q18CX4,GenBank,CAJ67054,,,630,fliW,,,,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,flagellar assembly factor,,,,increased virulence (hypervirulence),,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34675903,PubMed,10.3389/fmicb.2021.735616,Front Microbiol. 2021 Oct 5;12:735616,sun5@usf.edu,"Loss of fliW led to increased biofilm formation, cell adhesion, toxin production, and pathogenicity in a mouse model of C. difficile infection, while fliW-csrA codeletion decreased toxin production and mortality in vivo.",D Zhu 2021,2021,2 genes,Zhu-2021-FliW and CsrA Govern Flagellin (FliC),BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19112,PHI:11774,UniProt,Q18CX4,GenBank,CAJ67054,,,630,fliW,,,,,,PHI:11775,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,flagellar assembly factor,,,,reduced virulence,,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34675903,PubMed,10.3389/fmicb.2021.735616,Front Microbiol. 2021 Oct 5;12:735616,sun5@usf.edu,"Loss of fliW led to increased biofilm formation, cell adhesion, toxin production, and pathogenicity in a mouse model of C. difficile infection, while fliW-csrA codeletion decreased toxin production and mortality in vivo.",D Zhu 2021,2021,2 genes,Zhu-2021-FliW and CsrA Govern Flagellin (FliC),BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19113,PHI:11775,UniProt,Q18CX3,GenBank,CAJ67055,,,630,csrA,,,,,,PHI:11774,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,translational regulator,,,,reduced virulence,,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34675903,PubMed,10.3389/fmicb.2021.735616,Front Microbiol. 2021 Oct 5;12:735616,sun5@usf.edu,"Loss of fliW led to increased biofilm formation, cell adhesion, toxin production, and pathogenicity in a mouse model of C. difficile infection, while fliW-csrA codeletion decreased toxin production and mortality in vivo.",D Zhu 2021,2021,2 genes,Zhu-2021-FliW and CsrA Govern Flagellin (FliC),BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19114,PHI:11774,UniProt,Q18CX4,GenBank,CAJ67054,,,630,fliW,,,,,,,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,primates,9606,Homo sapiens (related: human),HCT-8 cells,,,HCT-8 cell,flagellar assembly factor,,,,increased virulence (hypervirulence),,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34675903,PubMed,10.3389/fmicb.2021.735616,Front Microbiol. 2021 Oct 5;12:735616,sun5@usf.edu,"Loss of fliW led to increased biofilm formation, cell adhesion, toxin production, and pathogenicity in a mouse model of C. difficile infection, while fliW-csrA codeletion decreased toxin production and mortality in vivo.",D Zhu 2021,2021,2 genes,Zhu-2021-FliW and CsrA Govern Flagellin (FliC),BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19115,PHI:11774,UniProt,Q18CX4,GenBank,CAJ67054,,,630,fliW,,,,,,PHI:11775,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,primates,9606,Homo sapiens (related: human),HCT-8 cells,,,HCT-8 cell,flagellar assembly factor,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34675903,PubMed,10.3389/fmicb.2021.735616,Front Microbiol. 2021 Oct 5;12:735616,sun5@usf.edu,"Loss of fliW led to increased biofilm formation, cell adhesion, toxin production, and pathogenicity in a mouse model of C. difficile infection, while fliW-csrA codeletion decreased toxin production and mortality in vivo.",D Zhu 2021,2021,2 genes,Zhu-2021-FliW and CsrA Govern Flagellin (FliC),BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19116,PHI:11775,UniProt,Q18CX3,GenBank,CAJ67055,,,630,csrA,,,,,,PHI:11774,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,primates,9606,Homo sapiens (related: human),HCT-8 cells,,,HCT-8 cell,translational regulator,,,,unaffected pathogenicity,,,,,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34675903,PubMed,10.3389/fmicb.2021.735616,Front Microbiol. 2021 Oct 5;12:735616,sun5@usf.edu,"Loss of fliW led to increased biofilm formation, cell adhesion, toxin production, and pathogenicity in a mouse model of C. difficile infection, while fliW-csrA codeletion decreased toxin production and mortality in vivo.",D Zhu 2021,2021,2 genes,Zhu-2021-FliW and CsrA Govern Flagellin (FliC),BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19117,PHI:11776,,no data found,,,,,,ArsR6 (BSS2_RS07325),,,,,,,29461,Brucella suis,1004954,S2,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,arsenic acid-resistant (ArsR) family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,polymyxin B; H2O2; sorbitol,polymyxin B: CHEBI:8309; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34639201,PubMed,10.3390/ijms221910860,Int J Mol Sci. 2021 Oct 8;22(19):10860,wangaihua@nwafu.edu.cn,"ArsR6 (BSS2_RS07325) was required for Brucella survival both under heat, oxidative, and osmotic stress and in a murine infection model in vivo.",F Zhi 2021,2021,2 genes,Zhi-2021-An ArsR Transcriptional Regulator Fac,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19118,PHI:11777,UniProt,A0A7U8IWW6,GenBank,EEW91836,,,40,Omp25D,,,,,,,29461,Brucella suis,1004954,S2,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,polymyxin B; H2O2; sorbitol,polymyxin B: CHEBI:8309; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34639201,PubMed,10.3390/ijms221910860,Int J Mol Sci. 2021 Oct 8;22(19):10860,wangaihua@nwafu.edu.cn,Omp25D deletion strain attenuated in a murine infection model in vivo.,F Zhi 2021,2021,2 genes,Zhi-2021-An ArsR Transcriptional Regulator Fac,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19119,PHI:11776,,no data found,,,,,,ArsR6 (BSS2_RS07325),,,,,,,29461,Brucella suis,1004954,S2,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,arsenic acid-resistant (ArsR) family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,polymyxin B; H2O2; sorbitol,polymyxin B: CHEBI:8309; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34639201,PubMed,10.3390/ijms221910860,Int J Mol Sci. 2021 Oct 8;22(19):10860,wangaihua@nwafu.edu.cn,"ArsR6 (BSS2_RS07325) was required for Brucella survival both under heat, oxidative, and osmotic stress and in a murine infection model in vivo.",F Zhi 2021,2021,2 genes,Zhi-2021-An ArsR Transcriptional Regulator Fac,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19120,PHI:11777,UniProt,A0A7U8IWW6,GenBank,EEW91836,,,40,Omp25D,,,,,,,29461,Brucella suis,1004954,S2,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,arsenic acid-resistant (ArsR) family transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,polymyxin B; H2O2; sorbitol,polymyxin B: CHEBI:8309; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34639201,PubMed,10.3390/ijms221910860,Int J Mol Sci. 2021 Oct 8;22(19):10860,wangaihua@nwafu.edu.cn,Omp25D deletion strain attenuated in a murine infection model in vivo.,F Zhi 2021,2021,2 genes,Zhi-2021-An ArsR Transcriptional Regulator Fac,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19121,PHI:11778,UniProt,A4RE77,GenBank,EHA48668,,,70-15,Momyo1 (MGG_00748),chromosome 5,,,MoShe4 (MGG_03876),UniProt: G4NHC6; GenBank: EHA47636,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,myosin-1,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,,no,H2O2; NaCl; SDS; calcofluor white; Congo red,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: silencing,,,YVS,34536105,PubMed,10.1007/s00253-021-11573-8,Appl Microbiol Biotechnol. 2021 Oct;105(19):7395-7410,kandylemon@163.com,"Momyo1 was required for vegetative growth, conidiation, melanin pigmentation, and pathogenicity of M. oryzae.",C Zheng 2021,2021,1 gene,Zheng-2021-Class I myosin mediated endocytosis,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19122,PHI:11778,UniProt,A4RE77,GenBank,EHA48668,,,70-15,Momyo1 (MGG_00748),chromosome 5,,,MoShe4 (MGG_03876),UniProt: G4NHC6; GenBank: EHA47636,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,myosin-1,,,,reduced virulence,,yes,yes,,,reduced,,reduced; aberrant,,no,H2O2; NaCl; SDS; calcofluor white; Congo red,H2O2: CHEBI:16240; NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: silencing,,,YVS,34536105,PubMed,10.1007/s00253-021-11573-8,Appl Microbiol Biotechnol. 2021 Oct;105(19):7395-7410,kandylemon@163.com,"Momyo1 was required for vegetative growth, conidiation, melanin pigmentation, and pathogenicity of M. oryzae.",C Zheng 2021,2021,1 gene,Zheng-2021-Class I myosin mediated endocytosis,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19123,PHI:11779,UniProt,A0A1R4AEC9,GenBank,SJL30117,,,SU60,ppad,,,,,,,837,Porphyromonas gingivalis,242619,W83,ulcerative colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon; spleen,peptidylarginine deiminase,,,,reduced virulence,,,,,,,,,,no,dextran sodium sulfate,dextran sodium sulfate: CHEBI:116735,,,,,gene deletion: full; gene complementation,,,YVS,34593756,PubMed,10.1038/s41368-021-00136-2,Int J Oral Sci. 2021 Sep 30;13(1):31,yppan@cmu.edu.cn,Deleting PPAD reduced the severity of ulcerative colitis.,X Zhao 2021,2021,1 gene,Zhao-2021-Porphyromonas gingivalis exacerbates,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19124,PHI:11780,,no data found,,,,,,Cgppz1,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,anthracnose,eudicots,3690,Populus x canadensis (related: carolina poplar),,,,leaf,protein phosphatase,,,,reduced virulence,,yes,yes,,,,,reduced; aberrant,reduced,no,NaCl; KCl; CaCl2; LiCl; H2O2; calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate,NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; LiCl: CHEBI:48607; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34689611,PubMed,10.1094/PHYTO-02-21-0051-R,Phytopathology. 2021 Oct 23,lhuang@njfu.edu.cn,"The ΔCgppz1 mutant was hypersensitive to osmotic stresses, cell wall stressors, and oxidative stressors.",Y Z Zhang 2021,2021,1 gene,Zhang-2021-Protein Phosphatase CgPpz1 Regulate,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19125,PHI:11780,,no data found,,,,,,Cgppz1,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,anthracnose,flowering plants,215539,Liriodendron chinense x Liriodendron tulipifera (no common name found),,,,leaf,protein phosphatase,,,,reduced virulence,,yes,yes,,,,,reduced; aberrant,reduced,no,NaCl; KCl; CaCl2; LiCl; H2O2; calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate,NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; LiCl: CHEBI:48607; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34689611,PubMed,10.1094/PHYTO-02-21-0051-R,Phytopathology. 2021 Oct 23,lhuang@njfu.edu.cn,"The ΔCgppz1 mutant was hypersensitive to osmotic stresses, cell wall stressors, and oxidative stressors.",Y Z Zhang 2021,2021,1 gene,Zhang-2021-Protein Phosphatase CgPpz1 Regulate,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19126,PHI:11781,UniProt,A0A0A2KBK6,GenBank,KGO59810,,,MD-8,PeNoxA,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,riboflavin synthase-like beta-barrel,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,H2O2; Congo red (CR); sodium dodecyl sulfate,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34456938,PubMed,10.3389/fpls.2021.696210,Front Plant Sci. 2021 Aug 12;12:696210,biyang@gsau.edu.cn,The ΔPeNoxA strain negatively regulated the growth and development of P. expansum and did not show any significant effect on the pathogenicity.,X Zhang 2021,2021,3 genes,Zhang-2021-Protein Phosphatase CgPpz1 Regulate,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19127,PHI:11782,UniProt,A0A0A2JDZ1,GenBank,KGO53006,,,MD-8,PeNoxR,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,tetratricopeptide-like helical,,,,unaffected pathogenicity,,,,,,wild type,,increased,wild type,no,H2O2; Congo red (CR); sodium dodecyl sulfate,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34456938,PubMed,10.3389/fpls.2021.696210,Front Plant Sci. 2021 Aug 12;12:696210,biyang@gsau.edu.cn,The ΔPeNoxR strain showed no effect on the growth or pathogenicity of P. expansum in the apple fruits.,X Zhang 2021,2021,3 genes,Zhang-2021-Protein Phosphatase CgPpz1 Regulate,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19128,PHI:11783,UniProt,A0A0A2JSB8,GenBank,KGO57553,,,MD-8,PeRacA,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,"small GTPase superfamily, Rab type",,,,reduced virulence,,,,,,reduced,,reduced; aberrant,reduced,no,H2O2; Congo red (CR); sodium dodecyl sulfate,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34456938,PubMed,10.3389/fpls.2021.696210,Front Plant Sci. 2021 Aug 12;12:696210,biyang@gsau.edu.cn,The ΔPeRacA strain had a significant effect on the reduction of growth and pathogenicity.,X Zhang 2021,2021,3 genes,Zhang-2021-Protein Phosphatase CgPpz1 Regulate,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19129,PHI:11784,UniProt,A0A098DSY3,GenBank,CEF84477,,,PH-1,FgPse1 (FGSG_13254),chromosome 4,,,FgNab2,UniProt: I1RCG8; GenBank: CEF73390,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,inflorescence,importin N-terminal domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,reduced,no,H2O2; Congo red (CR); sodium dodecyl sulfate,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34784736,PubMed,10.1094/PHYTO-08-21-0357-R,Phytopathology. 2021 Nov 16,zhangsh2007@agri.gov.cn,"FgPse1 was required for mycelial growth, virulence and DON production by interacting with FgNab2 in F. graminearum.",L Zhang 2021,2021,1 gene,Zhang-2021-The importin FgPse1 is required for,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19130,PHI:11784,UniProt,A0A098DSY3,GenBank,CEF84477,,,PH-1,FgPse1 (FGSG_13254),chromosome 4,,,FgNab2,UniProt: I1RCG8; GenBank: CEF73390,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,kernel,importin N-terminal domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,reduced,no,H2O2; Congo red (CR); sodium dodecyl sulfate,H2O2: CHEBI:16240; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34784736,PubMed,10.1094/PHYTO-08-21-0357-R,Phytopathology. 2021 Nov 16,zhangsh2007@agri.gov.cn,"FgPse1 was required for mycelial growth, virulence and DON production by interacting with FgNab2 in F. graminearum.",L Zhang 2021,2021,1 gene,Zhang-2021-The importin FgPse1 is required for,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19131,PHI:11785,UniProt,A0A063C6C7,GenBank,GAO14748,,,IPU010,Uvsun1,,,,,,,1159556,Ustilaginoidea virens,,P1,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,spikelet,group-I SUN family protein,,,,reduced virulence,,,,,,reduced; abberant,,reduced; aberrant,aberrant,no,sodium dodecyl sulfate; calcofluor white; sorbitol; sodium chloride; hydrogen peroxide,sodium dodecyl sulfate: CHEBI:8984; calcofluor white: CHEBI:50011; sorbitol: CHEBI:17924; sodium chloride: CHEBI:26710; hydrogen peroxide: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34589077,PubMed,10.3389/fmicb.2021.739453,Front Microbiol. 2021 Sep 13;12:739453,liuyf@jaas.ac.cn,"Uvsun1 was required for growth, cell wall integrity and pathogenicity of U. virens.",M Yu 2021,2021,1 gene,Yu-2021-SUN-Family Protein UvSUN1 Regulates th,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19132,PHI:11786,,no data found,,,,,,atg4,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),B73 line,,,leaf,autophagy protein,,,,reduced virulence,,yes,yes,,,reduced,reduced,reduced; aberrant,reduced,no,NaCl; KCl; sodium dodecyl sulfate; sorbital; Congo red; azoxystrobin; boscalid,NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulfate: CHEBI:8984; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; azoxystrobin: CHEBI:40909; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34664975,PubMed,10.1094/PHYTO-06-21-0271-R,Phytopathology. 2021 Oct 19,zhangxianghui1982@126.com,The autophagy process was blocked and the virulence was reduced dramatically in ΔChatg4 and ΔChatg8 mutants.,H Yu 2021,2021,2 genes,Yu-2021-The autophagy genes ChATG4 and ChATG8,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19133,PHI:11787,UniProt,N4X184,GenBank,ENI06684,,,ATCC 48331,atg8,,,,,,,5016,Bipolaris maydis,665024,C4 (Tox1+ MAT1-2),southern corn leaf blight,monocots,4577,Zea mays (related: maize),B73 line,,,leaf,ubiquitin-like autophagy protein,,,,reduced virulence,,yes,yes,,,reduced,reduced,reduced; aberrant,reduced,no,NaCl; KCl; sodium dodecyl sulfate; sorbital; Congo red; azoxystrobin; boscalid,NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulfate: CHEBI:8984; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; azoxystrobin: CHEBI:40909; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34664975,PubMed,10.1094/PHYTO-06-21-0271-R,Phytopathology. 2021 Oct 19,zhangxianghui1982@126.com,The autophagy process was blocked and the virulence was reduced dramatically in ΔChatg4 and ΔChatg8 mutants.,H Yu 2021,2021,2 genes,Yu-2021-The autophagy genes ChATG4 and ChATG8,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19134,PHI:11788,UniProt,G4YJ98,GenBank,EGZ29432,,,P6497,PsPTL (PsSCP3),,,,,,,67593,Phytophthora sojae,1094619,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,seedling; hypocotyl,patched family protein,,,,unaffected pathogenicity,,,,,,,,reduced,wild type,no,KCl; sorbitol; H2O2; β-sitosterol,KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; β-sitosterol: CHEBI:27693,,,,,gene deletion: full,,,YVS,34690942,PubMed,10.3389/fmicb.2021.673784,Front Microbiol. 2021 Oct 7;12:673784,seedling@cau.edu.cn,"Deletion of PsPTL using CRISPR/Cas9 had no significant effect on the growth, development, or virulence of P. sojae.",Z Xue 2021,2021,1 gene,Xue-2021-A Patched-Like Protein PsPTL Is Not E,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19135,PHI:11789,UniProt,A0A0H2ZN44,GenBank,ABJ54596,,,D39,spd_1587 (MgaSpn),,,,,,,1313,Streptococcus pneumoniae,373153,D39,pneumonia,rodents,10090,Mus musculus (related: house mouse),CD-1,,,nasal lavage fluid; blood; spleen,"transcriptional activator, putative",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34506260,PubMed,10.1080/21505594.2021.1972539,Virulence. 2021 Dec;12(1):2366-2381,zheng_yuqiang@hospital.cqmu.edu.cn,The mgaSpn null mutant caused more severe systemic disease than the parental strain D39.,S Xiao 2021,2021,1 gene,Xiao-2021-MgaSpn is a negative regulator of ca,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19136,PHI:11789,UniProt,A0A0H2ZN44,GenBank,ABJ54596,,,D39,spd_1587 (MgaSpn),,,,,,,1313,Streptococcus pneumoniae,373153,D39,pneumonia,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,"transcriptional activator, putative",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34506260,PubMed,10.1080/21505594.2021.1972539,Virulence. 2021 Dec;12(1):2366-2381,zheng_yuqiang@hospital.cqmu.edu.cn,The mgaSpn null mutant caused more severe systemic disease than the parental strain D39.,S Xiao 2021,2021,1 gene,Xiao-2021-MgaSpn is a negative regulator of ca,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19137,PHI:11790,UniProt,L7HYB8,GenBank,ELQ35272,,,Y34,MoTwf,,,,,,,318829,Magnaporthe oryzae,1143189,Y34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,twinfilin,,,,reduced virulence,,,yes,yes,,,,reduced,,no,diphenylene iodonium chloride,diphenylene iodonium chloride: CHEBI:77967,,,,,gene deletion: full; gene complementation,,,YVS,34519407,PubMed,10.1111/mpp.13136,Mol Plant Pathol. 2021 Dec;22(12):1641-1655,dztang@genetics.ac.cn,MoTwf participated in the virulence of M. oryzae by organizing Spk-connected actin filaments and regulating MoHex1 distribution at the hyphal tip.,R Xu 2021,2021,1 gene,Xu-2021-Twinfilin regulates actin assembly and,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19138,PHI:11791,UniProt,Q8Y3F1,GenBank,CAD13557,,,GMI1000,gabT (RSc0029),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,stem,4-aminobutyrate aminotransaminase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34604716,PubMed,10.17912/micropub.biology.000478,MicroPubl Biol. 2021 Sep 29;2021:10.17912/micropub.biology.000478,alberto.macho@icloud.com,The gabT-encoded GABA transaminase was required for full virulence of R. solanacearum in a natural host plant.,L Xian 2021,2021,1 gene,Xian-2021-The GABA transaminase GabT is requir,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19139,PHI:11792,UniProt,P0DD43,GenBank,BAC63899,,,SSI-1,prsA1,,,,,,,1314,Streptococcus pyogenes,,serotype M4 strain 4063-05,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,foldase protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34592883,PubMed,10.1080/21505594.2021.1982501,Virulence. 2021 Dec;12(1):2633-2647,yungchiychang@ntu.edu.tw,"The inactivation of both PrsA in GAS caused remarkable impairment in biofilm formation, host adherence, infection-induced cytotoxicity, and in vivo virulence in a murine soft tissue infection model.",Z Y Wu 2021,2021,2 genes,Wu-2021-Unique virulence role of post-transloc,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19140,PHI:11793,UniProt,Q1J943,GenBank,ABF36968,,,MGAS10750,prsA2,,,,,,,1314,Streptococcus pyogenes,,serotype M4 strain 4063-05,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,ribose-phosphate pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34592883,PubMed,10.1080/21505594.2021.1982501,Virulence. 2021 Dec;12(1):2633-2647,yungchiychang@ntu.edu.tw,"The inactivation of both PrsA in GAS caused remarkable impairment in biofilm formation, host adherence, infection-induced cytotoxicity, and in vivo virulence in a murine soft tissue infection model.",Z Y Wu 2021,2021,2 genes,Wu-2021-Unique virulence role of post-transloc,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19141,PHI:11792,UniProt,P0DD43,GenBank,BAC63899,,,SSI-1,prsA1,,,,,,PHI:11793,1314,Streptococcus pyogenes,,serotype M4 strain 4063-05,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,foldase protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34592883,PubMed,10.1080/21505594.2021.1982501,Virulence. 2021 Dec;12(1):2633-2647,yungchiychang@ntu.edu.tw,"The inactivation of both PrsA in GAS caused remarkable impairment in biofilm formation, host adherence, infection-induced cytotoxicity, and in vivo virulence in a murine soft tissue infection model.",Z Y Wu 2021,2021,2 genes,Wu-2021-Unique virulence role of post-transloc,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19142,PHI:11793,UniProt,Q1J943,GenBank,ABF36968,,,MGAS10750,prsA2,,,,,,PHI:11792,1314,Streptococcus pyogenes,,serotype M4 strain 4063-05,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,ribose-phosphate pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34592883,PubMed,10.1080/21505594.2021.1982501,Virulence. 2021 Dec;12(1):2633-2647,yungchiychang@ntu.edu.tw,"The inactivation of both PrsA in GAS caused remarkable impairment in biofilm formation, host adherence, infection-induced cytotoxicity, and in vivo virulence in a murine soft tissue infection model.",Z Y Wu 2021,2021,2 genes,Wu-2021-Unique virulence role of post-transloc,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19143,PHI:11792,UniProt,P0DD43,GenBank,BAC63899,,,SSI-1,prsA1,,,,,,,1314,Streptococcus pyogenes,,serotype M4 strain 4063-05,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,rodents,10090,Mus musculus (related: house mouse),ICR,,,skin,foldase protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34592883,PubMed,10.1080/21505594.2021.1982501,Virulence. 2021 Dec;12(1):2633-2647,yungchiychang@ntu.edu.tw,"The inactivation of both PrsA in GAS caused remarkable impairment in biofilm formation, host adherence, infection-induced cytotoxicity, and in vivo virulence in a murine soft tissue infection model.",Z Y Wu 2021,2021,2 genes,Wu-2021-Unique virulence role of post-transloc,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19144,PHI:11793,UniProt,Q1J943,GenBank,ABF36968,,,MGAS10750,prsA2,,,,,,,1314,Streptococcus pyogenes,,serotype M4 strain 4063-05,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,rodents,10090,Mus musculus (related: house mouse),ICR,,,skin,ribose-phosphate pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34592883,PubMed,10.1080/21505594.2021.1982501,Virulence. 2021 Dec;12(1):2633-2647,yungchiychang@ntu.edu.tw,"The inactivation of both PrsA in GAS caused remarkable impairment in biofilm formation, host adherence, infection-induced cytotoxicity, and in vivo virulence in a murine soft tissue infection model.",Z Y Wu 2021,2021,2 genes,Wu-2021-Unique virulence role of post-transloc,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19145,PHI:11792,UniProt,P0DD43,GenBank,BAC63899,,,SSI-1,prsA1,,,,,,PHI:11793,1314,Streptococcus pyogenes,,serotype M4 strain 4063-05,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,rodents,10090,Mus musculus (related: house mouse),ICR,,,skin,foldase protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34592883,PubMed,10.1080/21505594.2021.1982501,Virulence. 2021 Dec;12(1):2633-2647,yungchiychang@ntu.edu.tw,"The inactivation of both PrsA in GAS caused remarkable impairment in biofilm formation, host adherence, infection-induced cytotoxicity, and in vivo virulence in a murine soft tissue infection model.",Z Y Wu 2021,2021,2 genes,Wu-2021-Unique virulence role of post-transloc,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19146,PHI:11793,UniProt,Q1J943,GenBank,ABF36968,,,MGAS10750,prsA2,,,,,,PHI:11792,1314,Streptococcus pyogenes,,serotype M4 strain 4063-05,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,rodents,10090,Mus musculus (related: house mouse),ICR,,,skin,ribose-phosphate pyrophosphokinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34592883,PubMed,10.1080/21505594.2021.1982501,Virulence. 2021 Dec;12(1):2633-2647,yungchiychang@ntu.edu.tw,"The inactivation of both PrsA in GAS caused remarkable impairment in biofilm formation, host adherence, infection-induced cytotoxicity, and in vivo virulence in a murine soft tissue infection model.",Z Y Wu 2021,2021,2 genes,Wu-2021-Unique virulence role of post-transloc,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19147,PHI:11794,UniProt,Q87AA4,GenBank,AAO29754,,,Temecula1,pilA1 (PD1924),,,,,,,2371,Xylella fastidiosa,183190,Stag's Leap,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),cv. Chardonnay,,,petiole,type IV pili subunit protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34787465,PubMed,10.1128/Spectrum.01591-21,Microbiol Spectr. 2021 Nov 17;9(3):e0159121,wei.wei2@usda.gov,Deleting pilA1 in X. fastidiosa strain Stag's Leap increased surface attachment in vitro and reduced virulence in grapevines.,W Wei 2021,2021,1 gene,"Wei-2021-Csp1, a Cold Shock Protein Homolog in",BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19148,PHI:11795,UniProt,B8NRK4,GenBank,QMW25250,,,NRRL3357,bioDA (ALFA_049090],chromosome 1,,,,,,5059,Aspergillus flavus,,CA14 (Δku70 ΔniaD ΔpyrG),ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,cotyledon,hypothetical protein,,,biotin synthesis,reduced virulence,,,,,,wild type,,reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34591470,PubMed,10.1021/acs.jafc.1c03248,J Agric Food Chem. 2021 Oct 13;69(40):11971-11981,wshyyl@sina.com,A. flavus bioDA mutant blocked biotin production and decreased its pathogenicity to infect peanuts.,W Wei 2021,2021,2 genes,Wei-2021-Characterization of the Bifunctional,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19149,PHI:11796,UniProt,A0A0M4AMY8,GenBank,ALB06114,,,03-8,VmEP1,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Gala 3,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,34691119,PubMed,10.3389/fpls.2021.741342,Front Plant Sci. 2021 Oct 7;12:741342,huanglili@nwsuaf.edu.cn,V. mali effector protein EP1 suppressed the host immune responses by interfering with the MdPR10-mediated resistance to V. mali during the infection.,W Wang 2021,2021,1 gene,Wang-2021-A Valsa mali Effector Protein 1 Targ,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19150,PHI:11796,UniProt,A0A0M4AMY8,GenBank,ALB06114,,,03-8,VmEP1,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Gala 3,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient overexpression,,,YVS,34691119,PubMed,10.3389/fpls.2021.741342,Front Plant Sci. 2021 Oct 7;12:741342,huanglili@nwsuaf.edu.cn,V. mali effector protein EP1 suppressed the host immune responses by interfering with the MdPR10-mediated resistance to V. mali during the infection.,W Wang 2021,2021,1 gene,Wang-2021-A Valsa mali Effector Protein 1 Targ,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19151,PHI:11796,UniProt,A0A0M4AMY8,GenBank,ALB06114,,,03-8,VmEP1,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,4100,Nicotiana benthamiana (no common name found),cv. Gala 3,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,34691119,PubMed,10.3389/fpls.2021.741342,Front Plant Sci. 2021 Oct 7;12:741342,huanglili@nwsuaf.edu.cn,V. mali effector protein EP1 suppressed the host immune responses by interfering with the MdPR10-mediated resistance to V. mali during the infection.,W Wang 2021,2021,1 gene,Wang-2021-A Valsa mali Effector Protein 1 Targ,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19152,PHI:11797,UniProt,Q0P7J8,GenBank,CAJ76292,,,IHE3034,clbH,,,,,,,562,Escherichia coli,,APEC XM,infection,rodents,10090,Mus musculus (related: house mouse),b.End3 cell line,,,brain microvascular endothelial cell,colibactin non-ribosomal peptide synthetase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34529552,PubMed,10.1080/21505594.2021.1972538,Virulence. 2021 Dec;12(1):2382-2399,mengxia_1@126.com,Colibactin did not contribute to the adhesion and invasion of bEnd.3 cells.,P Wang 2021,2021,1 gene,Wang-2021-Colibactin in avian pathogenic Esche,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19153,PHI:11797,UniProt,Q0P7J8,GenBank,CAJ76292,,,IHE3034,clbH,,,,,,,562,Escherichia coli,,APEC XM,infection,rodents,10090,Mus musculus (related: house mouse),ICR,,,brain; lung; blood,colibactin non-ribosomal peptide synthetase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34529552,PubMed,10.1080/21505594.2021.1972538,Virulence. 2021 Dec;12(1):2382-2399,mengxia_1@126.com,Meningitis did not occur in APEC ΔclbH-infected mice in vivo.,P Wang 2021,2021,1 gene,Wang-2021-Colibactin in avian pathogenic Esche,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19154,PHI:11798,UniProt,M4UPW3,GenBank,AGH87242,,,FQY_4,yceI (AVT05_RS03545),,,,,,,305,Ralstonia solanacearum,,RS-T02,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhenlong 2,,,root; stem,polyisoprenoid-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,34576877,PubMed,10.3390/microorganisms9091982,Microorganisms. 2021 Sep 17;9(9):1982,dehong@gxu.edu.cn,The DM3545 strain showed substantially reduced virulence toward tomato plants than its wild-type and OE3545 counterpart.,K H Wang 2021,2021,1 gene,Wang-2021-A yceI Gene Involves in the Adaptati,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19155,PHI:11798,UniProt,M4UPW3,GenBank,AGH87242,,,FQY_4,yceI (AVT05_RS03545),,,,,,,305,Ralstonia solanacearum,,RS-T02,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhenlong 2,,,root; stem,polyisoprenoid-binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,NaCl,NaCl: CHEBI:26710,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34576877,PubMed,10.3390/microorganisms9091982,Microorganisms. 2021 Sep 17;9(9):1982,dehong@gxu.edu.cn,The DM3545 strain showed substantially reduced virulence toward tomato plants than its wild-type and OE3545 counterpart.,K H Wang 2021,2021,1 gene,Wang-2021-A yceI Gene Involves in the Adaptati,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19156,PHI:11799,UniProt,Q2FZ97,GenBank,ABD30252,,,NCTC 8325,mraZ,,,,,,,1280,Staphylococcus aureus,1242971,MW2,endocarditis; osteomyelitis; pneumonia; septic shock,primates,9606,Homo sapiens (related: human),,,,neutrophil,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34754202,PubMed,10.2147/IDR.S332777,Infect Drug Resist. 2021 Nov 2;14:4539-4551,wzjxyfy@163.com,The mraZ deletion mutant led to significantly reduced resistance to human neutrophils and decreased virulence in Galleria mellonella model as well as mouse skin and soft tissue infection models.,B Wang 2021,2021,1 gene,Wang-2021-Functional Insights of MraZ on the P,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19157,PHI:11799,UniProt,Q2FZ97,GenBank,ABD30252,,,NCTC 8325,mraZ,,,,,,,1280,Staphylococcus aureus,1242971,MW2,endocarditis; osteomyelitis; pneumonia; septic shock,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34754202,PubMed,10.2147/IDR.S332777,Infect Drug Resist. 2021 Nov 2;14:4539-4551,wzjxyfy@163.com,The mraZ deletion mutant led to significantly reduced resistance to human neutrophils and decreased virulence in Galleria mellonella model as well as mouse skin and soft tissue infection models.,B Wang 2021,2021,1 gene,Wang-2021-Functional Insights of MraZ on the P,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19158,PHI:11799,UniProt,Q2FZ97,GenBank,ABD30252,,,NCTC 8325,mraZ,,,,,,,1280,Staphylococcus aureus,1242971,MW2,endocarditis; osteomyelitis; pneumonia; septic shock,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34754202,PubMed,10.2147/IDR.S332777,Infect Drug Resist. 2021 Nov 2;14:4539-4551,wzjxyfy@163.com,The mraZ deletion mutant led to significantly reduced resistance to human neutrophils and decreased virulence in Galleria mellonella model as well as mouse skin and soft tissue infection models.,B Wang 2021,2021,1 gene,Wang-2021-Functional Insights of MraZ on the P,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19159,PHI:11800,UniProt,G2X9I0,GenBank,EGY15648,,,VdLs.17,noxA (VDAG_06812),chromosome 8,,,,,,27337,Verticillium dahliae,,123V,Verticillium wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,NADPH oxidase A,,,,reduced virulence,,,yes,,,wild type,,reduced; aberrant,reduced,no,H2O2; paraquat; iprodione; N-acetyl cysteine; NaCl; sorbitol; amphotericin B; calcofluor white M2R; Congo red; CaCl2; CuSO4; FeSO4; azoxystrobin; sodium cyanide; pyraclostrobin; kresoxim-methyl; annisulborn; sodium amytal; flutolanil; isopyrazam; fluconazole; rapamycin,"H2O2: CHEBI:16240; paraquat: CHEBI:34905; iprodione: CHEBI:28909; N-acetyl cysteine: CHEBI:28939; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; FeSO4: CHEBI:75832; azoxystrobin: CHEBI:40909; sodium cyanide: CHEBI:33192; pyraclostrobin: CHEBI:78780; kresoxim-methyl: CHEBI:2962; annisulborn,  sodium amytal: CHEBI:2673; flutolanil: CHEBI:81792; isopyrazam: CHEBI:83126; rapamycin: CHEBI:9168",,,,,gene deletion: full; gene complementation,,,YVS,34575778,PubMed,10.3390/jof7090740,J Fungi (Basel). 2021 Sep 9;7(9):740,matypas@biol.uoa.gr,"NoxA, but Not Yap1, was essential for the penetration ability and pathogenicity of V. dahliae.",V Vangalis 2021,2021,2 genes,Vangalis-2021-The NADPH Oxidase A of Verticill,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19160,PHI:11801,UniProt,G2WSJ2,GenBank,EGY17906,,,VdLs.17,yap1 (VDAG_01588),chromosome 1,,,,,,27337,Verticillium dahliae,,123V,Verticillium wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,transcription factor,,,,unaffected pathogenicity,,,no,,,reduced,,reduced,wild type,no,H2O2; paraquat; iprodione; N-acetyl cysteine; NaCl; sorbitol; amphotericin B; calcofluor white M2R; Congo red; CaCl2; CuSO4; FeSO4; azoxystrobin; sodium cyanide; pyraclostrobin; kresoxim-methyl; annisulborn; sodium amytal; flutolanil; isopyrazam; fluconazole; rapamycin,"H2O2: CHEBI:16240; paraquat: CHEBI:34905; iprodione: CHEBI:28909; N-acetyl cysteine: CHEBI:28939; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; FeSO4: CHEBI:75832; azoxystrobin: CHEBI:40909; sodium cyanide: CHEBI:33192; pyraclostrobin: CHEBI:78780; kresoxim-methyl: CHEBI:2962; annisulborn,  sodium amytal: CHEBI:2673; flutolanil: CHEBI:81792; isopyrazam: CHEBI:83126; rapamycin: CHEBI:9168",,,,,gene deletion: full; gene complementation,,,YVS,34575778,PubMed,10.3390/jof7090740,J Fungi (Basel). 2021 Sep 9;7(9):740,matypas@biol.uoa.gr,"NoxA, but Not Yap1, was essential for the penetration ability and pathogenicity of V. dahliae.",V Vangalis 2021,2021,2 genes,Vangalis-2021-The NADPH Oxidase A of Verticill,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19161,PHI:11801,UniProt,G2WSJ2,GenBank,EGY17906,,,VdLs.17,yap1 (VDAG_01588),chromosome 1,,,,,,27337,Verticillium dahliae,,123V,Verticillium wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,transcription factor,,,,reduced virulence,,,yes,,,wild type,,reduced; aberrant,reduced,no,H2O2; paraquat; iprodione; N-acetyl cysteine; NaCl; sorbitol; amphotericin B; calcofluor white M2R; Congo red; CaCl2; CuSO4; FeSO4; azoxystrobin; sodium cyanide; pyraclostrobin; kresoxim-methyl; annisulborn; sodium amytal; flutolanil; isopyrazam; fluconazole; rapamycin,"H2O2: CHEBI:16240; paraquat: CHEBI:34905; iprodione: CHEBI:28909; N-acetyl cysteine: CHEBI:28939; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; FeSO4: CHEBI:75832; azoxystrobin: CHEBI:40909; sodium cyanide: CHEBI:33192; pyraclostrobin: CHEBI:78780; kresoxim-methyl: CHEBI:2962; annisulborn,  sodium amytal: CHEBI:2673; flutolanil: CHEBI:81792; isopyrazam: CHEBI:83126; rapamycin: CHEBI:9168",,,,,gene deletion: full; gene complementation,,,YVS,34575778,PubMed,10.3390/jof7090740,J Fungi (Basel). 2021 Sep 9;7(9):740,matypas@biol.uoa.gr,"NoxA, but Not Yap1, was essential for the penetration ability and pathogenicity of V. dahliae.",V Vangalis 2021,2021,2 genes,Vangalis-2021-The NADPH Oxidase A of Verticill,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19162,PHI:11802,UniProt,G4NFS4,GenBank,EHA46881,,,70-15,FAE1 (MGG_08737),chromosome 6,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,feruloyl esterase,,,,reduced virulence,,yes,yes,yes,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34524467,PubMed,10.1007/s00294-021-01213-z,Curr Genet. 2021 Sep 15,rajeshpatkar@iitb.ac.in,"While deletion of FAE1 in M. oryzae did not affect the vegetative growth and asexual development, the fae1Δ mutant showed significantly reduced pathogenesis on rice plants, mainly due to impaired host invasion and colonisation.",A Thaker 2021,2021,1 gene,Thaker-2021-Feruloyl esterase Fae1 is required,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19163,PHI:11802,UniProt,G4NFS4,GenBank,EHA46881,,,70-15,FAE1 (MGG_08737),chromosome 6,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,feruloyl esterase,,,,reduced virulence,,yes,yes,yes,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34524467,PubMed,10.1007/s00294-021-01213-z,Curr Genet. 2021 Sep 15,rajeshpatkar@iitb.ac.in,"While deletion of FAE1 in M. oryzae did not affect the vegetative growth and asexual development, the fae1Δ mutant showed significantly reduced pathogenesis on rice plants, mainly due to impaired host invasion and colonisation.",A Thaker 2021,2021,1 gene,Thaker-2021-Feruloyl esterase Fae1 is required,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19164,PHI:11803,,no data found,,,,,,aflrlm1,,,,,,,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,CWI transcription factor,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34693219,PubMed,10.1016/j.isci.2021.103159,iScience. 2021 Sep 23;24(10):103159,wshyyl@sina.com,"AflRlm1 played a positive role in conidia production, sclerotium formation, a?atoxin biosynthesis, and pathogenicity.",C Tan 2021,2021,3 genes,Tan-2021-CWI pathway participated in vegetativ,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19165,PHI:11803,,no data found,,,,,,aflrlm1,,,,,,,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,cotyledon,CWI transcription factor,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34693219,PubMed,10.1016/j.isci.2021.103159,iScience. 2021 Sep 23;24(10):103159,wshyyl@sina.com,"AflRlm1 played a positive role in conidia production, sclerotium formation, a?atoxin biosynthesis, and pathogenicity.",C Tan 2021,2021,3 genes,Tan-2021-CWI pathway participated in vegetativ,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19166,PHI:11804,,no data found,,,,,,aflwsc1,,,,,,,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,cell wall integrity and stress response component protein,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34693219,PubMed,10.1016/j.isci.2021.103159,iScience. 2021 Sep 23;24(10):103159,wshyyl@sina.com,WSC double knock out reduced sporulation capacity and infection pathogenicity.,C Tan 2021,2021,3 genes,Tan-2021-CWI pathway participated in vegetativ,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19167,PHI:11805,,no data found,,,,,,aflwsc2,,,,,,,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,cell wall integrity and stress response component protein,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34693219,PubMed,10.1016/j.isci.2021.103159,iScience. 2021 Sep 23;24(10):103159,wshyyl@sina.com,WSC double knock out reduced sporulation capacity and infection pathogenicity.,C Tan 2021,2021,3 genes,Tan-2021-CWI pathway participated in vegetativ,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19168,PHI:11804,,no data found,,,,,,aflwsc1,,,,,,PHI:11805,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,cell wall integrity and stress response component protein,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34693219,PubMed,10.1016/j.isci.2021.103159,iScience. 2021 Sep 23;24(10):103159,wshyyl@sina.com,WSC double knock out reduced sporulation capacity and infection pathogenicity.,C Tan 2021,2021,3 genes,Tan-2021-CWI pathway participated in vegetativ,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19169,PHI:11805,,no data found,,,,,,aflwsc2,,,,,,PHI:11804,5059,Aspergillus flavus,,CA14 (Δku70 ΔpyrG),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,cell wal lintegrity and stress response component protein,,,aflatoxin biosynthesis,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34693219,PubMed,10.1016/j.isci.2021.103159,iScience. 2021 Sep 23;24(10):103159,wshyyl@sina.com,WSC double knock out reduced sporulation capacity and infection pathogenicity.,C Tan 2021,2021,3 genes,Tan-2021-CWI pathway participated in vegetativ,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19170,PHI:11806,UniProt,A7ET79,GenBank,EDN92671,,,1980,SsTrx1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,stem rot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,thioredoxin 1,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,34459563,PubMed,10.1111/mpp.13127,Mol Plant Pathol. 2021 Nov;22(11):1413-1426,dding1989@163.com,"RNA interference-induced silencing of SsTrx1 in S. sclerotiorum affected the hyphal growth rate, mycelial morphology, and sclerotial development under in vitro conditions.",K Rana 2021,2021,1 gene,Rana-2021-Sclerotinia sclerotiorum Thioredoxin,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19171,PHI:11806,UniProt,A7ET79,GenBank,EDN92671,,,1980,SsTrx1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,stem rot,eudicots,3708,Brassica napus (related: rape),cv. Zhongshuang 11,,,leaf,thioredoxin 1,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,34459563,PubMed,10.1111/mpp.13127,Mol Plant Pathol. 2021 Nov;22(11):1413-1426,dding1989@163.com,"RNA interference-induced silencing of SsTrx1 in S. sclerotiorum affected the hyphal growth rate, mycelial morphology, and sclerotial development under in vitro conditions.",K Rana 2021,2021,1 gene,Rana-2021-Sclerotinia sclerotiorum Thioredoxin,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19172,PHI:11806,UniProt,A7ET79,GenBank,EDN92671,,,1980,SsTrx1,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,stem rot,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,thioredoxin 1,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,34459563,PubMed,10.1111/mpp.13127,Mol Plant Pathol. 2021 Nov;22(11):1413-1426,dding1989@163.com,"RNA interference-induced silencing of SsTrx1 in S. sclerotiorum affected the hyphal growth rate, mycelial morphology, and sclerotial development under in vitro conditions.",K Rana 2021,2021,1 gene,Rana-2021-Sclerotinia sclerotiorum Thioredoxin,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19173,PHI:11807,UniProt,A0A0D6GJV1,GenBank,AVG62829,,,FDAARGOS_6,ohyA,,,,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,skin,oleate hydratase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34817231,PubMed,10.1128/Spectrum.01546-21,Microbiol Spectr. 2021 Nov 24;9(3):e0154621,charles.rock@stjude.org,"Wild-type and ΔohyA strains were equally infective in the neutropenic thigh model, but recovery of the ΔohyA strain was 2 orders of magnitude lower in the immunocompetent skin infection model.",C D Radka 2021,2021,1 gene,Radka-2021-Oleate Hydratase (OhyA) Is a Virule,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19174,PHI:11807,UniProt,A0A0D6GJV1,GenBank,AVG62829,,,FDAARGOS_6,ohyA,,,,,,,1280,Staphylococcus aureus,,AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,thigh,oleate hydratase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34817231,PubMed,10.1128/Spectrum.01546-21,Microbiol Spectr. 2021 Nov 24;9(3):e0154621,charles.rock@stjude.org,"Wild-type and ΔohyA strains were equally infective in the neutropenic thigh model, but recovery of the ΔohyA strain was 2 orders of magnitude lower in the immunocompetent skin infection model.",C D Radka 2021,2021,1 gene,Radka-2021-Oleate Hydratase (OhyA) Is a Virule,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19175,PHI:11808,UniProt,G4MXC6,GenBank,EHA56024,,,70-15,PoRal2 (MGG_08255),chromosome 2,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,Kelch and BTB domain protein,,,,reduced virulence,,yes,yes,,,,,reduced,wild type,no,sucrose; sorbitol; NaCl; Congo red; calcofluor white,sucrose: CHEBI:17992; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,34589096,PubMed,10.3389/fpls.2021.702368,Front Plant Sci. 2021 Sep 13;12:702368,fuchenglin@zju.edu.cn,"PoRal2 was involved in sporulation, aerial hypha and conidiophore differentiation, appressorium formation, plant penetration, and virulence.",Y Qu 2021,2021,1 gene,Qu-2021-PoRal2 Is Involved in Appressorium For,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19176,PHI:11808,UniProt,G4MXC6,GenBank,EHA56024,,,70-15,PoRal2 (MGG_08255),chromosome 2,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,Kelch and BTB domain protein,,,,reduced virulence,,yes,yes,,,,,reduced,wild type,no,sucrose; sorbitol; NaCl; Congo red; calcofluor white,sucrose: CHEBI:17992; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,YVS,34589096,PubMed,10.3389/fpls.2021.702368,Front Plant Sci. 2021 Sep 13;12:702368,fuchenglin@zju.edu.cn,"PoRal2 was involved in sporulation, aerial hypha and conidiophore differentiation, appressorium formation, plant penetration, and virulence.",Y Qu 2021,2021,1 gene,Qu-2021-PoRal2 Is Involved in Appressorium For,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19177,PHI:11809,UniProt,O07424,GenBank,CCP42906,,,H37Rv,Rv0180c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,probable conserved transmembrane protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate,sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34724002,PubMed,10.1371/journal.ppat.1010020,PLoS Pathog. 2021 Nov 1;17(11):e1010020,Christophe.Guilhot@ipbs.fr,Deletion of rv0180c in M. tuberculosis substantially reduced the initiation of infection in the lungs of mice.,D Payros 2021,2021,1 gene,Payros-2021-Rv0180c contributes to Mycobacteri,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19178,PHI:11809,UniProt,O07424,GenBank,CCP42906,,,H37Rv,Rv0180c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),HMDM cells,,,macrophage,probable conserved transmembrane protein,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate,sodium dodecyl sulfate: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34724002,PubMed,10.1371/journal.ppat.1010020,PLoS Pathog. 2021 Nov 1;17(11):e1010020,Christophe.Guilhot@ipbs.fr,"Rv0180c enhanced entry into macrophages through the use of complement-receptor 3 (CR3), a major phagocytic receptor for M. tuberculosis.",D Payros 2021,2021,1 gene,Payros-2021-Rv0180c contributes to Mycobacteri,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19179,PHI:11810,,no data found,,,,,,drk1,,,,,,,121759,Paracoccidioides brasiliensis,502780,Pb18,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,dimorphism regulating-histidine kinase,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; Congo red; itraconazole; caspofungin,NaCl: CHEBI:26710; Congo red: CHEBI:34653; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180,,,,,altered gene expression / gene regulation: silencing,,,YVS,34682273,PubMed,10.3390/jof7100852,J Fungi (Basel). 2021 Oct 12;7(10):852,maria.giannini@unesp.br,PbDRK1 silencing affected the virulence of P. brasiliensis in G. mellonella model.,C M Marcos 2021,2021,1 gene,"Marcos-2021-Drk1, a Dimorphism Histidine Kinas",BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19180,PHI:11811,UniProt,X2JLZ0,GenBank,AHN60101,,,05ZYH33,htpsC,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),Hep-2 cell line,,,HEp-2 cell,type II histidine triad protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34491523,PubMed,10.1007/s12275-021-1129-1,J Microbiol. 2021 Oct;59(10):949-957,anniecao2001@163.com,The htpsC deletion strain exhibited a diminished ability to adhere to and invade epithelial cells from different sources.,Y Lu 2021,2021,1 gene,Lu-2021-The type II histidine triad protein Ht,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19181,PHI:11811,UniProt,X2JLZ0,GenBank,AHN60101,,,05ZYH33,htpsC,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,type II histidine triad protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34491523,PubMed,10.1007/s12275-021-1129-1,J Microbiol. 2021 Oct;59(10):949-957,anniecao2001@163.com,The htpsC deletion strain exhibited a diminished ability to adhere to and invade epithelial cells from different sources.,Y Lu 2021,2021,1 gene,Lu-2021-The type II histidine triad protein Ht,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19182,PHI:11811,UniProt,X2JLZ0,GenBank,AHN60101,,,05ZYH33,htpsC,,,,,,,1307,Streptococcus suis,391295,05ZYH33,streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,type II histidine triad protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34491523,PubMed,10.1007/s12275-021-1129-1,J Microbiol. 2021 Oct;59(10):949-957,anniecao2001@163.com,The htpsC deletion strain exhibited a diminished ability to adhere to and invade epithelial cells from different sources.,Y Lu 2021,2021,1 gene,Lu-2021-The type II histidine triad protein Ht,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19183,PHI:11812,,no data found,GenBank,QNN07660,,,K56-2,tecA,chromosome 2,,,,,,95486,Burkholderia cenocepacia,,J2315,cystic fibrosis-like disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34579569,PubMed,10.1128/mBio.02098-21,mBio. 2021 Oct 26;12(5):e0209821,james.bliska@dartmouth.edu,"TecA was a B. cenocepacia virulence factor that exacerbates lung inflammation, weight loss, and lethality in mouse infection models.",N A Loeven 2021,2021,1 gene,Loeven-2021-The Burkholderia cenocepacia Type,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19184,PHI:11813,,no data found,GenBank,XP_045260975,,,Lc1,CgMFS1,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,major facilitator superfamily transporter,,,,reduced virulence,,no,,,,,,reduced,wild type,no,NaCl; H2O2; Congo red; fludioxonil; iprodione; tebuconazole; triadiMefon,NaCl: CHEBI:26710; H2O2: CHEBI:16240; Congo red: CHEBI:34653; fludioxonil: CHEBI:81763; iprodione: CHEBI:28909; tebuconazole: CHEBI:81781; triadimefon: CHEBI:9665,,,,,gene deletion: full; gene complementation,,,YVS,34698108,PubMed,10.3390/cimb43030109,Curr Issues Mol Biol. 2021 Oct 11;43(3):1548-1557,anbang@hainanu.edu.cn,"The pathogenicity of ΔCgMFS1 was significantly impaired in the mutant, although its appressorium formation was not affected.",N Liu 2021,2021,1 gene,"Liu-2021-CgMFS1, a Major Facilitator Superfami",BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19185,PHI:11814,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,isolate 529L harboring distinct Ece1p isoform variant,,,,,5476,Candida albicans,237561,SC5314,vulvovaginal candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,vagina,"candidalysin, a cytolytic peptide toxin",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34506615,PubMed,10.1371/journal.ppat.1009884,PLoS Pathog. 2021 Sep 10;17(9):e1009884,brian.peters@uthsc.edu,Expression of the ECE1 open reading frame (ORF) from 529L in an SC5314-derived ece1Δ/Δ strain resulted in significantly reduced vaginopathogenicity as compared to an isogenic control expressing a wild-type (WT) ECE1 allele.,J Liu 2021,2021,1 gene,Liu-2021-A variant ECE1 allele contributes to,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19186,PHI:11814,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,isolate 529L harboring distinct Ece1p isoform variant,,,,,5476,Candida albicans,237561,SC5314,vulvovaginal candidiasis,primates,9606,Homo sapiens (related: human),A431 cell line,,,vaginal epithelial cell line,"candidalysin, a cytolytic peptide toxin",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34506615,PubMed,10.1371/journal.ppat.1009884,PLoS Pathog. 2021 Sep 10;17(9):e1009884,brian.peters@uthsc.edu,Expression of the ECE1 open reading frame (ORF) from 529L in an SC5314-derived ece1Δ/Δ strain resulted in significantly reduced vaginopathogenicity as compared to an isogenic control expressing a wild-type (WT) ECE1 allele.,J Liu 2021,2021,1 gene,Liu-2021-A variant ECE1 allele contributes to,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19187,PHI:11815,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,"FeSO4; 2,2'-bipyridine","FeSO4: CHEBI:75832; 2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34675899,PubMed,10.3389/fmicb.2021.725194,Front Microbiol. 2021 Oct 5;12:725194,huxiunian@163.com,"Strains with high OmpA protein expression were more invasive, which was a key determinant of A. baumannii infection and pathogenicity.",H Liu 2021,2021,1 gene,Liu-2021-Iron-Rich Conditions Induce OmpA and,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19188,PHI:11815,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,OmpA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,"FeSO4; 2,2'-bipyridine","FeSO4: CHEBI:75832; 2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34675899,PubMed,10.3389/fmicb.2021.725194,Front Microbiol. 2021 Oct 5;12:725194,huxiunian@163.com,"Strains with high OmpA protein expression were more invasive, which was a key determinant of A. baumannii infection and pathogenicity.",H Liu 2021,2021,1 gene,Liu-2021-Iron-Rich Conditions Induce OmpA and,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19189,PHI:11816,UniProt,P0CT07,GenBank,EHA47669,,,70-15,MoOeIF3K,chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,eukaryotic translation initiation factor 3 subunit K,,,,reduced virulence,,yes,yes,,,reduced,,reduced,,no,sodium dodecyl sulfate; NaCl,sodium dodecyl sulfate: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,34733303,PubMed,10.3389/fpls.2021.748120,Front Plant Sci. 2021 Oct 18;12:748120,jk_norvienyeku@hainanu.edu.cn,"MoOeIF3k promotes the initiation and development of the rice blast disease by positively regulating the mobilization and degradation of glycogen, appressorium integrity, host penetration, and colonization during host-pathogen interaction.",L Lin 2021,2021,1 gene,Lin-2021-eIF3k Domain-Containing Protein Regul,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19190,PHI:11816,UniProt,P0CT07,GenBank,EHA47669,,,70-15,MoOeIF3K,chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,eukaryotic translation initiation factor 3 subunit K,,,,reduced virulence,,yes,yes,,,reduced,,reduced,,no,sodium dodecyl sulfate; NaCl,sodium dodecyl sulfate: CHEBI:8984; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,34733303,PubMed,10.3389/fpls.2021.748120,Front Plant Sci. 2021 Oct 18;12:748120,jk_norvienyeku@hainanu.edu.cn,"MoOeIF3k promotes the initiation and development of the rice blast disease by positively regulating the mobilization and degradation of glycogen, appressorium integrity, host penetration, and colonization during host-pathogen interaction.",L Lin 2021,2021,1 gene,Lin-2021-eIF3k Domain-Containing Protein Regul,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19191,PHI:11817,UniProt,Q4WRC4,GenBank,EAL91008,,,Af293,AflkhA (AFUA_1G16780),chromosome 1,,,,,,746128,Aspergillus fumigatus,,AFIR928,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,"protein kinase, putative",,,,reduced virulence,,,,,,reduced,reduced,reduced,reduced,no,calcofluor white; Congo red; H2O2; menadione; KCl; NaCl; EDTA; EGTA; tunicamycin; dithiothreitol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; KCl: CHEBI:32588; NaCl: CHEBI:26710; EDTA: CHEBI:64758; EGTA: CAS:67-42-5; tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,34722342,PubMed,10.3389/fcimb.2021.756206,Front Cell Infect Microbiol. 2021 Oct 13;11:756206,hmpark@cnu.ac.kr,"Deletion of AflkhA resulted in defects in colonial growth, production of conidia, and sexual development.",J Y Lim 2021,2021,1 gene,"Lim-2021-The LAMMER Kinase, LkhA, Affects Aspe",BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19192,PHI:11817,UniProt,Q4WRC4,GenBank,EAL91008,,,Af293,AflkhA (AFUA_1G16780),chromosome 1,,,,,,746128,Aspergillus fumigatus,,AFIR928,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),MH-S cell line,,,alveolar macrophage,"protein kinase, putative",,,,reduced virulence,,,,,,reduced,reduced,reduced,reduced,no,calcofluor white; Congo red; H2O2; menadione; KCl; NaCl; EDTA; EGTA; tunicamycin; dithiothreitol,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; KCl: CHEBI:32588; NaCl: CHEBI:26710; EDTA: CHEBI:64758; EGTA: CAS:67-42-5; tunicamycin: CHEBI:29699; dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,YVS,34722342,PubMed,10.3389/fcimb.2021.756206,Front Cell Infect Microbiol. 2021 Oct 13;11:756206,hmpark@cnu.ac.kr,"Deletion of AflkhA resulted in defects in colonial growth, production of conidia, and sexual development.",J Y Lim 2021,2021,1 gene,"Lim-2021-The LAMMER Kinase, LkhA, Affects Aspe",BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19193,PHI:11818,UniProt,A0A1D8PUD2,GenBank,AOW31733,,,SC5314,atp16,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,oral candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; brain; liver; spleen,δ subunit of fungal F1Fo-ATP synthase,,,,reduced virulence,,,,,,,,reduced,,no,SDS; calcofluor white; caspofungin,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,34654833,PubMed,10.1038/s41467-021-26313-9,Nat Commun. 2021 Oct 15;12(1):6041,tzhangh@jnu.edu.cn,The ATP16-deleted mutant displayed downregulation of virulence factors and reduced pathogenicity.,S Li 2021,2021,1 gene,Li-2021-The d subunit of F(1)F(o)-ATP synthase,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19194,PHI:11818,UniProt,A0A1D8PUD2,GenBank,AOW31733,,,SC5314,atp16,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,oral candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,δ subunit of fungal F1Fo-ATP synthase,,,,reduced virulence,,,,,,,,reduced,,no,SDS; calcofluor white; caspofungin,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,YVS,34654833,PubMed,10.1038/s41467-021-26313-9,Nat Commun. 2021 Oct 15;12(1):6041,tzhangh@jnu.edu.cn,The ATP16-deleted mutant displayed downregulation of virulence factors and reduced pathogenicity.,S Li 2021,2021,1 gene,Li-2021-The d subunit of F(1)F(o)-ATP synthase,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19195,PHI:11819,UniProt,G4N3Q0,GenBank,EHA51874,,,70-15,MoRPD3 (MGG_05857),chromosome 3,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nagdong,,,leaf,histone deacetylase,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,increased; aberrant,reduced,wild type,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,YVS,34781734,PubMed,10.1128/mBio.02600-21,mBio. 2021 Nov 16:e0260021,jjeon@yu.ac.kr,"The MoRPD3 knock down strain showed a significant reduction in pathogenicity, which can be attributed to the delay in appressorium-mediated penetration and impaired invasive growth.",S H Lee 2021,2021,1 gene,"Lee-2021-A Histone Deacetylase, Magnaporthe or",BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19196,PHI:11820,UniProt,A0A1D8PGB7,GenBank,AOW27185,,,SC5314,ENT2 (C2_01390W),chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,oral candidiasis,primates,9606,Homo sapiens (related: human),VK2/E6E7 cell line,,,VK-2/E6E7 cell,epsin,,,,reduced virulence,,,,,,,,reduced,,no,sodium dodecyl sulfate; calcofluor white; Congo red; caspofungin; amphotericin B; fluconazole; KCl; NaCl; LiCl,sodium dodecyl sulfate: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; caspofungin: CHEBI:474180; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; KCl: CHEBI:32588; NaCl: CHEBI:26710; LiCl: CHEBI:48607,,,,,gene deletion: full; gene complementation,,,YVS,34585966,PubMed,10.1128/mSphere.00707-21,mSphere. 2021 Oct 27;6(5):e0070721,samuel.a.lee@dartmouth.edu,"C. albicans ENT2 had a role in efficient endocytosis, a process that was required for maintaining cell wall integrity, hyphal formation, and virulence-defining traits.",C Rollenhagen 2021,2021,1 gene,Rollenhagen-2021-Candida albicans ENT2 Contrib,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19197,PHI:11821,UniProt,P71560,GenBank,CCP43698,,,H37Rv,Rv0950c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,putative M23-domain containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34784363,PubMed,10.1371/journal.pone.0259181,PLoS One. 2021 Nov 16;16(11):e0259181,bavesh.kana@nhls.ac.za,"Deletion of Rv0950c yielded no defects in growth, colony morphology, antibiotic susceptibility or intracellular survival but caused a reduction in cell length.",A O Papadopoulos 2021,2021,1 gene,Papadopoulos-2021-Characterisation of a putati,BATCH_109B,2021-12-01,MC,,,,,,,,,,,,,
,,Record 19198,PHI:11822,UniProt,B8F6T4,GenBank,ACL33036,,,SH0165,htrA,,,,,,,738,Glaesserella parasuis,,CF7066,Glasser's disease,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,nasal cavity; trachea; lung; blood; joint,protease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34482810,PubMed,10.1080/21505594.2021.1966996,Virulence. 2021 Dec;12(1):2296-2313,wangxr228@mail.hzau.edu.cn,"Deletion of the htrA gene in G. parasuis led to severe defects in E-cadherin ectodomain cleavage, cell adherence and paracellular transmigration in vitro, as well as bacterial breaking through the tracheal epithelial cells, systemic invasion and dissemination in vivo. Host gene alteration data available for E-cadherin.",Q Cao 2021,2021,1 gene,Cao-2021-Cleavage of E-cadherin by porcine res,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19199,PHI:11822,UniProt,B8F6T4,GenBank,ACL33036,,,SH0165,htrA,,,,,,,738,Glaesserella parasuis,,CF7066,Glasser's disease,even-toed ungulates,9823,Sus scrofa (related: Pig),NPTr cell line,,,tracheal epithelium,protease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34482810,PubMed,10.1080/21505594.2021.1966996,Virulence. 2021 Dec;12(1):2296-2313,wangxr228@mail.hzau.edu.cn,The ΔhtrA strain exhibited a severe defect in the adhesion of both the wild-type NPTr cells and the E-Cad KO cells.,Q Cao 2021,2021,1 gene,Cao-2021-Cleavage of E-cadherin by porcine res,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19200,PHI:11823,,no data found,,,,,,yp1,,,,,,,632,Yersinia pestis,992166,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,small open reading frame (sORF)-encoded peptide,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34728737,PubMed,10.1038/s42003-021-02759-x,Commun Biol. 2021 Nov 2;4(1):1248,cjia@mail.ncpsb.org.cn,Remarkable attenuation of virulence in mice was observed in the SEP-deleted mutants.,S Cao 2021,2021,2 genes,Cao-2021-Proteogenomic discovery of sORF-encod,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19201,PHI:11824,,no data found,,,,,,yp2,,,,,,,632,Yersinia pestis,992166,201,plague,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,small open reading frame (sORF)-encoded peptide,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34728737,PubMed,10.1038/s42003-021-02759-x,Commun Biol. 2021 Nov 2;4(1):1248,cjia@mail.ncpsb.org.cn,Remarkable attenuation of virulence in mice was observed in the SEP-deleted mutants.,S Cao 2021,2021,2 genes,Cao-2021-Proteogenomic discovery of sORF-encod,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19202,PHI:11823,,no data found,,,,,,yp1,,,,,,,632,Yersinia pestis,992166,201,plague,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small open reading frame (sORF)-encoded peptide,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34728737,PubMed,10.1038/s42003-021-02759-x,Commun Biol. 2021 Nov 2;4(1):1248,cjia@mail.ncpsb.org.cn,Remarkable attenuation of virulence in mice was observed in the SEP-deleted mutants.,S Cao 2021,2021,2 genes,Cao-2021-Proteogenomic discovery of sORF-encod,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19203,PHI:11824,,no data found,,,,,,yp2,,,,,,,632,Yersinia pestis,992166,201,plague,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small open reading frame (sORF)-encoded peptide,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34728737,PubMed,10.1038/s42003-021-02759-x,Commun Biol. 2021 Nov 2;4(1):1248,cjia@mail.ncpsb.org.cn,Remarkable attenuation of virulence in mice was observed in the SEP-deleted mutants.,S Cao 2021,2021,2 genes,Cao-2021-Proteogenomic discovery of sORF-encod,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19204,PHI:11825,UniProt,G4N8C1,GenBank,EHA50168,,,70-15,MoTPS2 (MGG_03441),chromosome 4,,,MoTPS1,UniProt: G4NHF4; GenBank: EHA47664,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,trehalose-phosphatase,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced; aberrant,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34609170,PubMed,10.1128/mSystems.00462-21,mSystems. 2021 Oct 26;6(5):e0046221,wangxr228@mail.hzau.edu.cn,"MoTps2 was critical for vegetative growth, conidiogenesis, and pathogenicity in M. oryzae.",X Chen 2021,2021,3 genes,Chen-2021-Trehalose Phosphate Synthase Complex,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19205,PHI:11825,UniProt,G4N8C1,GenBank,EHA50168,,,70-15,MoTPS2 (MGG_03441),chromosome 4,,,MoTPS1,UniProt: G4NHF4; GenBank: EHA47664,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,trehalose-phosphatase,,,,reduced virulence,,yes,yes,yes,,reduced; aberrant,,reduced; aberrant,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34609170,PubMed,10.1128/mSystems.00462-21,mSystems. 2021 Oct 26;6(5):e0046221,wangxr228@mail.hzau.edu.cn,"MoTps2 was critical for vegetative growth, conidiogenesis, and pathogenicity in M. oryzae.",X Chen 2021,2021,3 genes,Chen-2021-Trehalose Phosphate Synthase Complex,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19206,PHI:11826,UniProt,G4NHF4,GenBank,EHA47664,,,70-15,MoTPS1,chromosome 6,,,MoTPS2 (MGG_03441); MoTPS3 (MGG_14118),UniProt: G4N8C1; GenBank: EHA50168; UniProt: G4NFU6; GenBank: EHA46903,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,trehalose-6-phosphate synthase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34609170,PubMed,10.1128/mSystems.00462-21,mSystems. 2021 Oct 26;6(5):e0046221,wangxr228@mail.hzau.edu.cn,"Deletion of MoTPS1 partially recovered the defects of the ΔMotps2 mutant in hyphal growth, conidiogenesis, virulence, and cell wall polymer deposition.",X Chen 2021,2021,3 genes,Chen-2021-Trehalose Phosphate Synthase Complex,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19207,PHI:11826,UniProt,G4NHF4,GenBank,EHA47664,,,70-15,MoTPS1,chromosome 6,,,MoTPS2 (MGG_03441); MoTPS3 (MGG_14118),UniProt: G4N8C1; GenBank: EHA50168; UniProt: G4NFU6; GenBank: EHA46903,PHI:11825,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,trehalose-6-phosphate synthase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34609170,PubMed,10.1128/mSystems.00462-21,mSystems. 2021 Oct 26;6(5):e0046221,wangxr228@mail.hzau.edu.cn,"Deletion of MoTPS1 partially recovered the defects of the ΔMotps2 mutant in hyphal growth, conidiogenesis, virulence, and cell wall polymer deposition.",X Chen 2021,2021,3 genes,Chen-2021-Trehalose Phosphate Synthase Complex,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19208,PHI:11825,UniProt,G4N8C1,GenBank,EHA50168,,,70-15,MoTPS2 (MGG_03441),chromosome 4,,,MoTPS1,UniProt: G4NHF4; GenBank: EHA47664,PHI:11826,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,trehalose-phosphatase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34609170,PubMed,10.1128/mSystems.00462-21,mSystems. 2021 Oct 26;6(5):e0046221,wangxr228@mail.hzau.edu.cn,"Deletion of MoTPS1 partially recovered the defects of the ΔMotps2 mutant in hyphal growth, conidiogenesis, virulence, and cell wall polymer deposition.",X Chen 2021,2021,3 genes,Chen-2021-Trehalose Phosphate Synthase Complex,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19209,PHI:11825,UniProt,G4N8C1,GenBank,EHA50168,,,70-15,MoTPS2 (MGG_03441),chromosome 4,,,MoTPS1,UniProt: G4NHF4; GenBank: EHA47664,PHI:11827,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,trehalose-phosphatase,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34609170,PubMed,10.1128/mSystems.00462-21,mSystems. 2021 Oct 26;6(5):e0046221,wangxr228@mail.hzau.edu.cn,Mutation of MoTPS3 suppressed MoTps1 activity to reduce the intracellular level of T6P and partially restore ΔMotps2 defects.,X Chen 2021,2021,3 genes,Chen-2021-Trehalose Phosphate Synthase Complex,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19210,PHI:11827,UniProt,G4NFU6,GenBank,EHA46903,,,70-15,MoTPS3 (MGG_14118),chromosome 6,,,MoTPS1,UniProt: G4NHF4; GenBank: EHA47664,PHI:11825,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,glyco_transf_20 domain-containing protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; Congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene mutation,,,YVS,34609170,PubMed,10.1128/mSystems.00462-21,mSystems. 2021 Oct 26;6(5):e0046221,wangxr228@mail.hzau.edu.cn,Mutation of MoTPS3 suppressed MoTps1 activity to reduce the intracellular level of T6P and partially restore ΔMotps2 defects.,X Chen 2021,2021,3 genes,Chen-2021-Trehalose Phosphate Synthase Complex,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19211,PHI:11828,UniProt,Q56977,GenBank,CAA63386,,,EV76,ymt,,,,,,,632,Yersinia pestis,,pCH16,pneumonic plague,fleas,163159,Xenopsylla cheopis (related: Oriental rat flea),,,,,Yersinia murine toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34648607,PubMed,10.1371/journal.ppat.1009995,PLoS Pathog. 2021 Oct 14;17(10):e1009995,david.bland@nih.gov,"Ymt greatly enhanced Y. pestis survival in fleas infected with bacteremic mouse, human, or black rat blood. In contrast, Ymt was much less important when fleas were infected using brown rat blood.",D M Bland 2021,2021,1 gene,Bland-2021-Acquisition of yersinia murine toxi,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19212,PHI:11829,,no data found,GenBank,ABO12996,,,ATCC 17978,entA (A1S_2579),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"23-dihydro-2,3-dihydroxybenzoate dehydrogenase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19213,PHI:11830,UniProt,A3M7A4,GenBank,ABO12798,,,ATCC 17978,basG (A1S_2379),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,N-hydroxyhistamine synthesis,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19214,PHI:11831,,no data found,GenBank,ABO12803,,,ATCC 17978,basC (A1S_2384),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative histamine N-monooxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19215,PHI:11832,UniProt,A0A0M3FPT8,GenBank,MQZ40370,,,AMA33,basD,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,acinetobactin non-ribosomal peptide synthetase subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19216,PHI:11833,,no data found,GenBank,ABO12809,,,ATCC 17978,basB (A1S_2390),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative acinetobactin biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19217,PHI:11834,,no data found,GenBank,ABO12804,,,ATCC 17978,bauA (A1S_2385),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative ferric acinetobactin receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19218,PHI:11835,,no data found,GenBank,ABO12791,,,ATCC 17978,basJ (A1S_2372),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative acinetobactin biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19219,PHI:11836,,no data found,GenBank,ABO12799,,,ATCC 17978,basF (A1S_2380),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative acinetobactin biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19220,PHI:11837,,no data found,GenBank,ABO12792,,,ATCC 17978,basI (A1S_2373),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative acinetobactin biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19221,PHI:11838,,no data found,GenBank,ABO12793,,,ATCC 17978,basH (A1S_2374),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative acinetobactin biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19222,PHI:11839,,no data found,GenBank,ABO12810,,,ATCC 17978,basA (A1S_2391),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative acinetobactin biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19223,PHI:11840,,no data found,GenBank,ABO12800,,,ATCC 17978,basE (A1S_2381),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative acinetobactin biosynthesis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19224,PHI:11841,UniProt,B0V5N5,GenBank,CAM87994,,,AYE,barA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19225,PHI:11842,,no data found,GenBank,ABO12794,,,ATCC 17978,barB (A1S_2375),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative ABC transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19226,PHI:11843,,no data found,GenBank,ABO12805,,,ATCC 17978,bauB (A1S_2386),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative ferric acinetobactin binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19227,PHI:11844,,no data found,GenBank,ABO12807,,,ATCC 17978,bauC (A1S_2388),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative ferric acinetobactin transport system permease protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19228,PHI:11845,,no data found,GenBank,ABO12808,,,ATCC 17978,bauD (A1S_2389),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative ferric acinetobactin transport system permease protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19229,PHI:11846,,no data found,GenBank,ABO12806,,,ATCC 17978,bauE (A1S_2387),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,ABC-type enterochelin transport system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19230,PHI:11847,,no data found,GenBank,ABO12811,,,ATCC 17978,bauF (A1S_2392),,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative acinetobactin utilization protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19231,PHI:11835,,no data found,GenBank,ABO12791,,,ATCC 17978,basJ (A1S_2372),,,,,,PHI:11848,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative acinetobactin biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19232,PHI:11848,,no data found,GenBank,ABO12998,,,ATCC 17978,fbsB (A1S_2581),,,,,,PHI:11835,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,isochorismate synthetase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19233,PHI:11836,,no data found,GenBank,ABO12799,,,ATCC 17978,basF (A1S_2380),,,,,,PHI:11849,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative acinetobactin biosynthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19234,PHI:11849,,no data found,GenBank,ABO12997,,,ATCC 17978,fbsC (A1S_2580),,,,,,PHI:11836,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"23-dihydro-2,3-dihydroxybenzoate synthetase, isochorismatase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34675911,PubMed,10.3389/fmicb.2021.752070,Front Microbiol. 2021 Oct 5;12:752070,laura.alvarez.fraga@sergas.es,"Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production.",K Conde-Pérez 2021,2021,21 genes,Conde-Pérez-2021-In-Depth Analysis of the Role,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19235,PHI:11850,,no data found,GenBank,WP_001072475,,,,LH92_RS01675,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,HlyD family secretion protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19236,PHI:11851,,no data found,GenBank,WP_000537695,,,,LH92_RS02585,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,type IV pilus biogenesis/stability protein PilW,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19237,PHI:11852,,no data found,GenBank,WP_000229914,,,,LH92_RS07135,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,malonate transporter subunit MadM,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19238,PHI:11853,,no data found,GenBank,WP_001046417,,,,LH92_RS15870,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,prepilin-type N-terminal cleavage/methylation domain-containing protein PilE,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19239,PHI:11854,,no data found,GenBank,WP_021510165,,,,LH92_RS16130,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,efflux RND transporter periplasmic adaptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19240,PHI:11855,,no data found,GenBank,WP_045900525,,,,LH92_RS16880,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,type VI secretion system protein VgrG,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19241,PHI:11856,,no data found,GenBank,WP_047479431,,,,LH92_RS00045,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ABC transporter ATP-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19242,PHI:11857,,no data found,GenBank,WP_079267361,,,,LH92_RS05285,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,amino acid permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19243,PHI:11858,,no data found,GenBank,WP_001162376,,,,LH92_RS08005,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,phosphoglycerate mutase family protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19244,PHI:11859,,no data found,GenBank,WP_004840631,,,,LH92_RS12010,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,multidrug efflux RND transporter outer membrane subunit AdeH,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19245,PHI:11860,,no data found,GenBank,WP_000521916,,,,LH92_RS16065,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sulfate ABC transporter substrate-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19246,PHI:11861,,no data found,GenBank,WP_161782838,,,,LH92_RS17175,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,PQQ-dependent sugar dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19247,PHI:11862,,no data found,GenBank,WP_000837758,,,,LH92_RS04440,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,energy transducer TonB,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19248,PHI:11863,,no data found,GenBank,WP_125535337,,,,LH92_RS05405,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,outer membrane porin family OprD,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19249,PHI:11864,,no data found,GenBank,WP_045899602,,,,LH92_RS06300,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,type VI secretion system-associated protein TagF,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19250,PHI:11865,,no data found,GenBank,WP_000996083,,,,LH92_RS06715,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,IclR family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19251,PHI:11866,,no data found,GenBank,WP_000669945,,,,LH92_RS13540,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hypothetical protein (putative lyase),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19252,PHI:11867,,no data found,GenBank,WP_001174793,,,,LH92_RS13935,,,,,,,470,Acinetobacter baumannii,,MAR002,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,multidrug efflux RND transporter outer membrane subunit AdeK,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34515614,PubMed,10.1080/21505594.2021.1950268,Virulence. 2021 Dec;12(1):2201-2213,jesus.aranda@uab.cat,Virulence assays showed the reduced pathogenicity of mutants with impairments in both types of motility or in surface-associated motility alone.,J Corral 2021,2021,18 genes,Corral-2021-Importance of twitching and surfac,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19253,PHI:11868,UniProt,A0A0E1PRN0,GenBank,BAN87892,,,NCGM 237,otsA,,,,,,,470,Acinetobacter baumannii,,AB5075,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,osmoregulatory trehalose synthesis protein A,,,trehalose synthesis pathway,reduced virulence,,,,,,,,reduced,,no,NaCl; colistin; vancomycin,NaCl: CHEBI:26710; colistin: CHEBI:37943; vancomycin: CHEBI:28001,,,,,gene deletion: full,,,YVS,34473830,PubMed,10.1093/glycob/cwab096,Glycobiology. 2021 Sep 3:cwab096,cszymans@uga.edu,"Trehalose-deficient otsA showed increased sensitivity to desiccation, colistin, serum complement and peripheral blood mononuclear cells, while trehalose-6-phosphate producing otsB behaved similar to the wild-type.",C S Crippen 2021,2021,2 genes,Crippen-2021-Trehalose-deficient Acinetobacter,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19254,PHI:11869,UniProt,A0A0E1PTM5,,,,,,otsB,,,,,,,470,Acinetobacter baumannii,,AB5075,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,osmoregulatory trehalose synthesis protein B,,,trehalose synthesis pathway,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl; colistin; vancomycin,NaCl: CHEBI:26710; colistin: CHEBI:37943; vancomycin: CHEBI:28001,,,,,gene deletion: full,,,YVS,34473830,PubMed,10.1093/glycob/cwab096,Glycobiology. 2021 Sep 3:cwab096,cszymans@uga.edu,"Trehalose-deficient otsA showed increased sensitivity to desiccation, colistin, serum complement and peripheral blood mononuclear cells, while trehalose-6-phosphate producing otsB behaved similar to the wild-type.",C S Crippen 2021,2021,2 genes,Crippen-2021-Trehalose-deficient Acinetobacter,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19255,PHI:11870,UniProt,D4F9X0,GenBank,EFE21438,,,ATCC 23685,cadA,,,,,,,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system protein,,,,reduced virulence,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19256,PHI:11871,UniProt,A0A2A7U510,GenBank,PEH73496,,,FDAARGOS_370,cadB,,,,,,,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19257,PHI:11870,UniProt,D4F9X0,GenBank,EFE21438,,,ATCC 23685,cadA,,,,,,PHI:11871,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system protein,,,,reduced virulence,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19258,PHI:11871,UniProt,A0A2A7U510,GenBank,PEH73496,,,FDAARGOS_370,cadB,,,,,,PHI:11870,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19259,PHI:11870,UniProt,D4F9X0,GenBank,EFE21438,,,ATCC 23685,cadA,,,,,,PHI:11872,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19260,PHI:11872,UniProt,D0ZCW9,GenBank,ACY83600,,,EIB202,cadC,,,,,,PHI:11870,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system membrane protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19261,PHI:11871,UniProt,A0A2A7U510,GenBank,PEH73496,,,FDAARGOS_370,cadB,,,,,,PHI:11872,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19262,PHI:11872,UniProt,D0ZCW9,GenBank,ACY83600,,,EIB202,cadC,,,,,,PHI:11871,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system membrane protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19263,PHI:11870,UniProt,D4F9X0,GenBank,EFE21438,,,ATCC 23685,cadA,,,,,,,636,Edwardsiella tarda,,TX01,edwardsiellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,lysine-dependent acid resistance (LDAR) system protein,,,,reduced virulence,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,"The deficiency of cadBA operon abated bacterial survival and replication in macrophages, and decreased bacterial dissemination in fish tissues.",C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19264,PHI:11871,UniProt,A0A2A7U510,GenBank,PEH73496,,,FDAARGOS_370,cadB,,,,,,,636,Edwardsiella tarda,,TX01,edwardsiellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,lysine-dependent acid resistance (LDAR) system membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,"The deficiency of cadBA operon abated bacterial survival and replication in macrophages, and decreased bacterial dissemination in fish tissues.",C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19265,PHI:11870,UniProt,D4F9X0,GenBank,EFE21438,,,ATCC 23685,cadA,,,,,,,636,Edwardsiella tarda,,TX01,edwardsiellosis,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,kidney; spleen; blood; liver,lysine-dependent acid resistance (LDAR) system protein,,,,reduced virulence,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,"The deficiency of cadBA operon abated bacterial survival and replication in macrophages, and decreased bacterial dissemination in fish tissues.",C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19266,PHI:11871,UniProt,A0A2A7U510,GenBank,PEH73496,,,FDAARGOS_370,cadB,,,,,,,636,Edwardsiella tarda,,TX01,edwardsiellosis,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,kidney; spleen; blood; liver,lysine-dependent acid resistance (LDAR) system membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,"The deficiency of cadBA operon abated bacterial survival and replication in macrophages, and decreased bacterial dissemination in fish tissues.",C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19267,PHI:11871,UniProt,A0A2A7U510,GenBank,PEH73496,,,FDAARGOS_370,cadB,,,,,,PHI:11870,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19268,PHI:11872,UniProt,D0ZCW9,GenBank,ACY83600,,,EIB202,cadC,,,,,,PHI:11870,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system membrane protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19269,PHI:11872,UniProt,D0ZCW9,GenBank,ACY83600,,,EIB202,cadC,,,,,,PHI:11871,636,Edwardsiella tarda,,TX01,edwardsiellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,lysine-dependent acid resistance (LDAR) system membrane protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,"diamide; 2,2'-dipyridyl","diamide: CHEBI:48958; 2,2'-dipyridyl: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34521475,PubMed,10.1186/s13567-021-00987-x,Vet Res. 2021 Sep 14;52(1):117,huyonghua@itbb.org.cn,The deletions of the cadBA operon reduced bacterial adhesion and invasion to Hela cells.,C Du 2021,2021,3 genes,Du-2021-Acid resistance system CadBA is implic,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19270,PHI:11873,UniProt,A0A3Y9SP29,GenBank,HAD2551688,,,Salmonella enterica subsp. enterica,SseK1,,S286Y SseK1,,,,,28901,Salmonella enterica,,,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,arginine-GlcNAc-transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34667584,PubMed,10.1039/d1sc04065k,Chem Sci. 2021 Aug 19;12(36):12181-12191,jangulo@us.es,"The integration of S286Y SseK1 and N302Y SseK2 mutants into S. enterica increased S. enterica survival in macrophages, suggesting that better enzymatic kinetic parameters lead to enhanced virulence.",A García-García 2021,2021,2 genes,García-García-2021-NleB_SseK-catalyzed arginin,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19271,PHI:11874,UniProt,A0A3U8GN84,GenBank,HAD1967974,,,Salmonella enterica subsp. enterica,SseK2,,N302Y SseK2,,,,,28901,Salmonella enterica,,,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,arginine-GlcNAc-transferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34667584,PubMed,10.1039/d1sc04065k,Chem Sci. 2021 Aug 19;12(36):12181-12191,jangulo@us.es,"The integration of S286Y SseK1 and N302Y SseK2 mutants into S. enterica increased S. enterica survival in macrophages, suggesting that better enzymatic kinetic parameters lead to enhanced virulence.",A García-García 2021,2021,2 genes,García-García-2021-NleB_SseK-catalyzed arginin,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19272,PHI:11875,,no data found,,,,,,Xress (ZY05719_RS04600),,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,antitoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34475853,PubMed,10.3389/fmicb.2021.671706,Front Microbiol. 2021 Aug 12;12:671706,panzihao@njau.edu.cn,The Xress deletion mutant was less pathogenic in vivo following a challenge in mice.,Q Gu 2021,2021,2 genes,Gu-2021-An Auto-Regulating Type II Toxin-Antit,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19273,PHI:11876,,no data found,,,,,,MNTss (ZY05719_RS04595),,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34475853,PubMed,10.3389/fmicb.2021.671706,Front Microbiol. 2021 Aug 12;12:671706,panzihao@njau.edu.cn,The Xress deletion mutant was less pathogenic in vivo following a challenge in mice.,Q Gu 2021,2021,2 genes,Gu-2021-An Auto-Regulating Type II Toxin-Antit,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19274,PHI:11875,,no data found,,,,,,Xress (ZY05719_RS04600),,,,,,PHI:11876,1307,Streptococcus suis,,ZY05719,meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,antitoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34475853,PubMed,10.3389/fmicb.2021.671706,Front Microbiol. 2021 Aug 12;12:671706,panzihao@njau.edu.cn,The Xress deletion mutant was less pathogenic in vivo following a challenge in mice.,Q Gu 2021,2021,2 genes,Gu-2021-An Auto-Regulating Type II Toxin-Antit,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19275,PHI:11876,,no data found,,,,,,MNTss (ZY05719_RS04595),,,,,,PHI:11875,1307,Streptococcus suis,,ZY05719,meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood; brain; liver; spleen,toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34475853,PubMed,10.3389/fmicb.2021.671706,Front Microbiol. 2021 Aug 12;12:671706,panzihao@njau.edu.cn,The Xress deletion mutant was less pathogenic in vivo following a challenge in mice.,Q Gu 2021,2021,2 genes,Gu-2021-An Auto-Regulating Type II Toxin-Antit,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19276,PHI:11875,,no data found,,,,,,Xress (ZY05719_RS04600),,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,antitoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34475853,PubMed,10.3389/fmicb.2021.671706,Front Microbiol. 2021 Aug 12;12:671706,panzihao@njau.edu.cn,The Xress deletion mutant was less pathogenic in vivo following a challenge in mice.,Q Gu 2021,2021,2 genes,Gu-2021-An Auto-Regulating Type II Toxin-Antit,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19277,PHI:11876,,no data found,,,,,,MNTss (ZY05719_RS04595),,,,,,,1307,Streptococcus suis,,ZY05719,meningitis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34475853,PubMed,10.3389/fmicb.2021.671706,Front Microbiol. 2021 Aug 12;12:671706,panzihao@njau.edu.cn,The Xress deletion mutant was less pathogenic in vivo following a challenge in mice.,Q Gu 2021,2021,2 genes,Gu-2021-An Auto-Regulating Type II Toxin-Antit,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19278,PHI:11875,,no data found,,,,,,Xress (ZY05719_RS04600),,,,,,PHI:11876,1307,Streptococcus suis,,ZY05719,meningitis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,antitoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34475853,PubMed,10.3389/fmicb.2021.671706,Front Microbiol. 2021 Aug 12;12:671706,panzihao@njau.edu.cn,The Xress deletion mutant was less pathogenic in vivo following a challenge in mice.,Q Gu 2021,2021,2 genes,Gu-2021-An Auto-Regulating Type II Toxin-Antit,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19279,PHI:11876,,no data found,,,,,,MNTss (ZY05719_RS04595),,,,,,PHI:11875,1307,Streptococcus suis,,ZY05719,meningitis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34475853,PubMed,10.3389/fmicb.2021.671706,Front Microbiol. 2021 Aug 12;12:671706,panzihao@njau.edu.cn,The Xress deletion mutant was less pathogenic in vivo following a challenge in mice.,Q Gu 2021,2021,2 genes,Gu-2021-An Auto-Regulating Type II Toxin-Antit,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19280,PHI:11877,UniProt,A0A194VVC8,GenBank,KUI67952,,,03-8,Vm-VPS10 (VM1G_02763),,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig,vacuolar protein sorting/targeting protein 10,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34759897,PubMed,10.3389/fmicb.2021.721399,Front Microbiol. 2021 Oct 1;12:721399,huanglili@nwsuaf.edu.cn,DCL2-dependent milRNA Vm-PC-3p-92107_6 played roles in pathogenicity by regulating the expression of Vm-VPS10.,F Guo 2021,2021,1 gene,Guo-2021-A Novel DCL2-Dependent Micro-Like RNA,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19281,PHI:11878,UniProt,A0A0K0GNJ3,GenBank,ACD60418,,,PXO99A,hrpX,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Taipei 309,,,leaf,AraC-family transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34731589,PubMed,10.1094/MPMI-05-21-0124-R,Mol Plant Microbe Interact. 2021 Nov 3:MPMI05210124R,pcronald@ucdavis.edu,RaxX-raxSTAB gene cluster transcription was activated by the HrpX protein required for pathogenesis.,A Joe 2021,2021,1 gene,Joe-2021-The HrpX Protein Activates Synthesis,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19282,PHI:11879,UniProt,G4N137,GenBank,EHA53213,,,70-15,TAS1 (MGG_07803),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143189,Y34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,TeA synthetase 1,,,tenuazonic acid (TeA) biosynthesis,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34755835,PubMed,10.1093/bbb/zbab195,Biosci Biotechnol Biochem. 2021 Nov 10:zbab195,cb-secretary@ml.riken.jp,"Although knockout of the TeA biosynthetic gene TAS1 did not affect the virulence of P. oryzae, constitutive TAS1 expression suppressed its infection.",T Kashiwa 2021,2021,1 gene,Kashiwa-2021-Tenuazonic acid production is dis,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19283,PHI:11879,UniProt,G4N137,GenBank,EHA53213,,,70-15,TAS1 (MGG_07803),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143189,Y34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,TeA synthetase 1,,,tenuazonic acid (TeA) biosynthesis,reduced virulence,,no,,,,,,,wild type,no,,,,,,,other evidence: constitutive expression,,,YVS,34755835,PubMed,10.1093/bbb/zbab195,Biosci Biotechnol Biochem. 2021 Nov 10:zbab195,cb-secretary@ml.riken.jp,"Although knockout of the TeA biosynthetic gene TAS1 did not affect the virulence of P. oryzae, constitutive TAS1 expression suppressed its infection.",T Kashiwa 2021,2021,1 gene,Kashiwa-2021-Tenuazonic acid production is dis,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19284,PHI:11880,,no data found,,,,,,reoM,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,regulator of MurA degradation,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34624065,PubMed,10.1371/journal.ppat.1009881,PLoS Pathog. 2021 Oct 8;17(10):e1009881,sauer3@wisc.edu,Deletion of reoM restored cell wall stress sensitivities and cytosolic survival defects of a ΔprkA mutant to nearly wild-type levels.,J L Kelliher 2021,2021,2 genes,Kelliher-2021-PASTA kinase-dependent control o,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19285,PHI:11880,,no data found,,,,,,reoM,,,,,,PHI:11881,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,regulator of MurA degradation,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34624065,PubMed,10.1371/journal.ppat.1009881,PLoS Pathog. 2021 Oct 8;17(10):e1009881,sauer3@wisc.edu,Deletion of reoM restored cell wall stress sensitivities and cytosolic survival defects of a ΔprkA mutant to nearly wild-type levels.,J L Kelliher 2021,2021,2 genes,Kelliher-2021-PASTA kinase-dependent control o,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19286,PHI:11881,,no data found,,,,,,prkA,,,,,,PHI:11880,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,penicillin binding protein and serine/threonine-associated (PASTA) kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34624065,PubMed,10.1371/journal.ppat.1009881,PLoS Pathog. 2021 Oct 8;17(10):e1009881,sauer3@wisc.edu,Deletion of reoM restored cell wall stress sensitivities and cytosolic survival defects of a ΔprkA mutant to nearly wild-type levels.,J L Kelliher 2021,2021,2 genes,Kelliher-2021-PASTA kinase-dependent control o,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19287,PHI:11882,UniProt,Q8ZQ03,GenBank,AAL20143,,,LT2,ycfR,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34659184,PubMed,10.3389/fmicb.2021.750940,Front Microbiol. 2021 Sep 30;12:750940,yoonh@ajou.ac.kr,Salmonella Typhimurium deprived of an outer membrane protein YcfR was attenuated in intracellular survival and exhibited downregulation in Salmonella pathogenicity island-2 (SPI-2) genes.,S I Kim 2021,2021,1 gene,Kim-2021-s(S)-Mediated Stress Response Induced,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19288,PHI:11882,UniProt,Q8ZQ03,GenBank,AAL20143,,,LT2,ycfR,,,,,,,28901,Salmonella enterica,1299114,subsp. enterica serovar Typhimurium strain ATCC 14028,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34659184,PubMed,10.3389/fmicb.2021.750940,Front Microbiol. 2021 Sep 30;12:750940,yoonh@ajou.ac.kr,Salmonella Typhimurium deprived of an outer membrane protein YcfR was attenuated in intracellular survival and exhibited downregulation in Salmonella pathogenicity island-2 (SPI-2) genes.,S I Kim 2021,2021,1 gene,Kim-2021-s(S)-Mediated Stress Response Induced,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19289,PHI:11883,,no data found,,,,,,sprY,,,,,,,1280,Staphylococcus aureus,,HG003,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),SWR,,,,small regulatory RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34554192,PubMed,10.1093/nar/gkab782,Nucleic Acids Res. 2021 Oct 11;49(18):10644-10656,svetlana.chabelskaia@univ-rennes1.fr,SprY decreased S. aureus hemolytic activity and virulence.,K B Le Huyen 2021,2021,1 gene,Le Huyen-2021-A small regulatory RNA alters St,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19290,PHI:11883,,no data found,,,,,,sprY,,,,,,,1280,Staphylococcus aureus,,HG001,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),SWR,,,,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34554192,PubMed,10.1093/nar/gkab782,Nucleic Acids Res. 2021 Oct 11;49(18):10644-10656,svetlana.chabelskaia@univ-rennes1.fr,SprY decreased S. aureus hemolytic activity and virulence.,K B Le Huyen 2021,2021,1 gene,Le Huyen-2021-A small regulatory RNA alters St,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19291,PHI:11883,,no data found,,,,,,sprY,,,,,,,1280,Staphylococcus aureus,,HG003,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,blood,small regulatory RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34554192,PubMed,10.1093/nar/gkab782,Nucleic Acids Res. 2021 Oct 11;49(18):10644-10656,svetlana.chabelskaia@univ-rennes1.fr,SprY decreased S. aureus hemolytic activity and virulence.,K B Le Huyen 2021,2021,1 gene,Le Huyen-2021-A small regulatory RNA alters St,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19292,PHI:11883,,no data found,,,,,,sprY,,,,,,,1280,Staphylococcus aureus,,HG001,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,blood,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34554192,PubMed,10.1093/nar/gkab782,Nucleic Acids Res. 2021 Oct 11;49(18):10644-10656,svetlana.chabelskaia@univ-rennes1.fr,SprY decreased S. aureus hemolytic activity and virulence.,K B Le Huyen 2021,2021,1 gene,Le Huyen-2021-A small regulatory RNA alters St,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19293,PHI:11883,,no data found,,,,,,sprY,,,,,,,1280,Staphylococcus aureus,,HG003,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,small regulatory RNA,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34554192,PubMed,10.1093/nar/gkab782,Nucleic Acids Res. 2021 Oct 11;49(18):10644-10656,svetlana.chabelskaia@univ-rennes1.fr,SprY decreased S. aureus hemolytic activity and virulence.,K B Le Huyen 2021,2021,1 gene,Le Huyen-2021-A small regulatory RNA alters St,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19294,PHI:11883,,no data found,,,,,,sprY,,,,,,,1280,Staphylococcus aureus,,HG001,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,small regulatory RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34554192,PubMed,10.1093/nar/gkab782,Nucleic Acids Res. 2021 Oct 11;49(18):10644-10656,svetlana.chabelskaia@univ-rennes1.fr,SprY decreased S. aureus hemolytic activity and virulence.,K B Le Huyen 2021,2021,1 gene,Le Huyen-2021-A small regulatory RNA alters St,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19295,PHI:11884,,no data found,,,,,,VvrraA1,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),,,,ileum,protein regulator of RNase E activity,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34751908,PubMed,10.1007/s12275-021-1518-5,J Microbiol. 2021 Nov 9,mlee@hallym.ac.kr,"The VvrraA1-deleted strain (ΔVvrraA1) showed decreased motility, invasiveness, biofilm formation ability as well as virulence in mice.",J Lee 2021,2021,1 gene,Lee-2021-Regulator of ribonuclease activity mo,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19296,PHI:11884,,no data found,,,,,,VvrraA1,,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,protein regulator of RNase E activity,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34751908,PubMed,10.1007/s12275-021-1518-5,J Microbiol. 2021 Nov 9,mlee@hallym.ac.kr,"The VvrraA1-deleted strain (ΔVvrraA1) showed decreased motility, invasiveness, biofilm formation ability as well as virulence in mice.",J Lee 2021,2021,1 gene,Lee-2021-Regulator of ribonuclease activity mo,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19297,PHI:11885,,no data found,,,,,,STnc150,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small RNA,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34543394,PubMed,10.1093/femsle/fnab124,FEMS Microbiol Lett. 2021 Oct 4;368(18):fnab124,qj710625@shzu.edu.cn,"STnc150 strain exhibited delayed biofilm formation, enhanced adhesion to macrophages, significantly reduced LD50, increased liver and spleen viral loads and more vital pathological damaging ability than its parent and complementary strains.",J Li 2021,2021,1 gene,Li-2021-sRNA STnc150 is involved in virulence,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19298,PHI:11885,,no data found,,,,,,STnc150,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; small intestine,small RNA,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34543394,PubMed,10.1093/femsle/fnab124,FEMS Microbiol Lett. 2021 Oct 4;368(18):fnab124,qj710625@shzu.edu.cn,"STnc150 strain exhibited delayed biofilm formation, enhanced adhesion to macrophages, significantly reduced LD50, increased liver and spleen viral loads and more vital pathological damaging ability than its parent and complementary strains.",J Li 2021,2021,1 gene,Li-2021-sRNA STnc150 is involved in virulence,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19299,PHI:11886,,no data found,GenBank,KFC01367,,,ATCC 19606,adh3 (DJ41_189),,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19300,PHI:11887,,no data found,GenBank,KFC01107,,,ATCC 19606,adh4 (DJ41_136),,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19301,PHI:11888,,no data found,GenBank,KFC02744,,,ATCC 19606,adh6 (DJ41_1604),,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19302,PHI:11886,,no data found,GenBank,KFC01367,,,ATCC 19606,adh3 (DJ41_189),,,,,,PHI:11887,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19303,PHI:11887,,no data found,GenBank,KFC01107,,,ATCC 19606,adh4 (DJ41_136),,,,,,PHI:11886,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19304,PHI:11886,,no data found,GenBank,KFC01367,,,ATCC 19606,adh3 (DJ41_189),,,,,,PHI:11888,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19305,PHI:11888,,no data found,GenBank,KFC02744,,,ATCC 19606,adh6 (DJ41_1604),,,,,,PHI:11886,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19306,PHI:11887,,no data found,GenBank,KFC01107,,,ATCC 19606,adh4 (DJ41_136),,,,,,PHI:11888,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19307,PHI:11888,,no data found,GenBank,KFC02744,,,ATCC 19606,adh6 (DJ41_1604),,,,,,PHI:11887,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19308,PHI:11886,,no data found,GenBank,KFC01367,,,ATCC 19606,adh3 (DJ41_189),,,,,,PHI:11887; PHI:11888,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19309,PHI:11887,,no data found,GenBank,KFC01107,,,ATCC 19606,adh4 (DJ41_136),,,,,,PHI:11886; PHI:11888,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19310,PHI:11888,,no data found,GenBank,KFC02744,,,ATCC 19606,adh6 (DJ41_1604),,,,,,PHI:11886; PHI:11887,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,iron-containing alcohol dehydrogenase family protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; tert-butyl hydroperoxide (TBHP),H2O2: CHEBI:16240; tert-butyl hydroperoxide (TBHP): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,YVS,34576087,PubMed,10.3390/ijms22189921,Int J Mol Sci. 2021 Sep 14;22(18):9921,hyshu@mail.cjcu.edu.tw,"Virulence assays performed on the Galleria mellonella model organism revealed that Adh4 mutants had comparable virulence to wild-type, while Adh3 and Adh6 mutants had reduced virulence.",G H Lin 2021,2021,3 genes,Lin-2021-Role of Iron-Containing Alcohol Dehyd,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19311,PHI:11889,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,ompA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),,,,spleen,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,"2,2'-bipyridine","2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34675899,PubMed,10.3389/fmicb.2021.725194,Front Microbiol. 2021 Oct 5;12:725194,huxiunian@163.com,"The levels of the inflammatory factors IL-1beta, IL-6, IL-8, and TNF-alpha in the mice spleen were significantly increased in the +ompA strain treatment group compared with the ΔompA strain group.",H Liu 2021,2021,1 gene,Liu-2021-Iron-Rich Conditions Induce OmpA and,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19312,PHI:11889,UniProt,Q6RYW5,GenBank,AAR83911,,,ATCC 19606,ompA,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,pneumonia,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein,,,,reduced virulence,,,,,,,,,,no,"2,2'-bipyridine","2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34675899,PubMed,10.3389/fmicb.2021.725194,Front Microbiol. 2021 Oct 5;12:725194,huxiunian@163.com,The ΔompA had a significantly reduced toxic effect on RAW246.7 macrophages.,H Liu 2021,2021,1 gene,Liu-2021-Iron-Rich Conditions Induce OmpA and,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19313,PHI:11890,UniProt,S8EVM9,GenBank,EPT27501,,,ME49,G3PDH,chromosome IX,,,,,,5811,Toxoplasma gondii,1080348,type I RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,glycerol-3-phosphate dehydrogenase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"2,2'-bipyridine","2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34499198,PubMed,10.1007/s00436-021-07308-3,Parasitol Res. 2021 Nov;120(11):3749-3759,wangmeng02@caas.com,"Compared with wild-type (WT) strains, the growth of RHΔG3PDH, RHΔTE, and RHΔDGAT in vitro and their virulence in vivo were not significantly different.",J Liu 2021,2021,4 genes,Liu-2021-Characterization of functions in para,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19314,PHI:11891,,no data found,,,,,,TE,,,,,,,5811,Toxoplasma gondii,1080348,type I RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,acyl-ACP thiolesterase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"2,2'-bipyridine","2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34499198,PubMed,10.1007/s00436-021-07308-3,Parasitol Res. 2021 Nov;120(11):3749-3759,wangmeng02@caas.com,"Compared with wild-type (WT) strains, the growth of RHΔG3PDH, RHΔTE, and RHΔDGAT in vitro and their virulence in vivo were not significantly different.",J Liu 2021,2021,4 genes,Liu-2021-Characterization of functions in para,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19315,PHI:11892,UniProt,A0A139Y444,GenBank,KYF45803,,,ARI,DGAT,,,,,,,5811,Toxoplasma gondii,1080348,type I RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,diacylglycerol acyltransferase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"2,2'-bipyridine","2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34499198,PubMed,10.1007/s00436-021-07308-3,Parasitol Res. 2021 Nov;120(11):3749-3759,wangmeng02@caas.com,"Compared with wild-type (WT) strains, the growth of RHΔG3PDH, RHΔTE, and RHΔDGAT in vitro and their virulence in vivo were not significantly different.",J Liu 2021,2021,4 genes,Liu-2021-Characterization of functions in para,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19316,PHI:11893,UniProt,A0A7J6K108,GenBank,KAF4640639,,,RH-88,FabD,chromosome X,,,,,,5811,Toxoplasma gondii,1080348,type I RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,malonyl CoA-acyl carrier protein transacylase,,,,reduced virulence,,,,,,,,wild type,,no,"2,2'-bipyridine","2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34499198,PubMed,10.1007/s00436-021-07308-3,Parasitol Res. 2021 Nov;120(11):3749-3759,wangmeng02@caas.com,The deletion of FabD attenuated the virulence of Type II Pru strain and reduced the formation of cysts in vivo,J Liu 2021,2021,4 genes,Liu-2021-Characterization of functions in para,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19317,PHI:11890,UniProt,S8EVM9,GenBank,EPT27501,,,ME49,G3PDH,chromosome IX,,,,,,5811,Toxoplasma gondii,1080348,type II strain Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,glycerol-3-phosphate dehydrogenase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"2,2'-bipyridine","2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34499198,PubMed,10.1007/s00436-021-07308-3,Parasitol Res. 2021 Nov;120(11):3749-3759,wangmeng02@caas.com,"Compared with wild-type (WT) strains, the growth of RHΔG3PDH, RHΔTE, and RHΔDGAT in vitro and their virulence in vivo were not significantly different.",J Liu 2021,2021,4 genes,Liu-2021-Characterization of functions in para,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19318,PHI:11891,,no data found,,,,,,TE,,,,,,,5811,Toxoplasma gondii,1080348,type II strain Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,acyl-ACP thiolesterase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"2,2'-bipyridine","2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34499198,PubMed,10.1007/s00436-021-07308-3,Parasitol Res. 2021 Nov;120(11):3749-3759,wangmeng02@caas.com,"Compared with wild-type (WT) strains, the growth of RHΔG3PDH, RHΔTE, and RHΔDGAT in vitro and their virulence in vivo were not significantly different.",J Liu 2021,2021,4 genes,Liu-2021-Characterization of functions in para,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19319,PHI:11892,UniProt,A0A139Y444,GenBank,KYF45803,,,ARI,DGAT,,,,,,,5811,Toxoplasma gondii,1080348,type II strain Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,diacylglycerol acyltransferase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,"2,2'-bipyridine","2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34499198,PubMed,10.1007/s00436-021-07308-3,Parasitol Res. 2021 Nov;120(11):3749-3759,wangmeng02@caas.com,"Compared with wild-type (WT) strains, the growth of RHΔG3PDH, RHΔTE, and RHΔDGAT in vitro and their virulence in vivo were not significantly different.",J Liu 2021,2021,4 genes,Liu-2021-Characterization of functions in para,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19320,PHI:11893,UniProt,A0A7J6K108,GenBank,KAF4640639,,,RH-88,FabD,chromosome X,,,,,,5811,Toxoplasma gondii,1080348,type II strain Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,malonyl CoA-acyl carrier protein transacylase,,,,reduced virulence,,,,,,,,wild type,,no,"2,2'-bipyridine","2,2'-bipyridine: CHEBI:30351",,,,,gene deletion: full; gene complementation,,,YVS,34499198,PubMed,10.1007/s00436-021-07308-3,Parasitol Res. 2021 Nov;120(11):3749-3759,wangmeng02@caas.com,The deletion of FabD attenuated the virulence of Type II Pru strain and reduced the formation of cysts in vivo,J Liu 2021,2021,4 genes,Liu-2021-Characterization of functions in para,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19321,PHI:11894,,no data found,,,,,,VmNLP1,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,necrosis and ethylene-inducing peptide 1(Nep1)-like protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,KCl; sorbitol; SDS; Congo red,KCl: CHEBI:32588; sorbitol: CHEBI:30911; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34682251,PubMed,10.3390/jof7100830,J Fungi (Basel). 2021 Oct 4;7(10):830,huanglili@nwsuaf.edu.cn,"VmNLP2 but not VmNLP1 induced cell death when transiently expressed in Nicotiana benthamiana. The peptide among VmNLP2, called nlp25 (VmNLP2), triggered strong immune response in Arabidopsis thaliana.",J Liu 2021,2021,2 genes,Liu-2021-Nep1-like Proteins from Valsa mali Di,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19322,PHI:11894,,no data found,,,,,,VmNLP1,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,necrosis and ethylene-inducing peptide 1(Nep1)-like protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,KCl; sorbitol; SDS; Congo red,KCl: CHEBI:32588; sorbitol: CHEBI:30911; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34682251,PubMed,10.3390/jof7100830,J Fungi (Basel). 2021 Oct 4;7(10):830,huanglili@nwsuaf.edu.cn,"VmNLP2 but not VmNLP1 induced cell death when transiently expressed in Nicotiana benthamiana. The peptide among VmNLP2, called nlp25 (VmNLP2), triggered strong immune response in Arabidopsis thaliana.",J Liu 2021,2021,2 genes,Liu-2021-Nep1-like Proteins from Valsa mali Di,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19323,PHI:11894,,no data found,,,,,,VmNLP1,VmNLP1H127Y,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,necrosis and ethylene-inducing peptide 1(Nep1)-like protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,KCl; sorbitol; SDS; Congo red,KCl: CHEBI:32588; sorbitol: CHEBI:30911; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene mutation,,,YVS,34682251,PubMed,10.3390/jof7100830,J Fungi (Basel). 2021 Oct 4;7(10):830,huanglili@nwsuaf.edu.cn,"VmNLP2 but not VmNLP1 induced cell death when transiently expressed in Nicotiana benthamiana. The peptide among VmNLP2, called nlp25 (VmNLP2), triggered strong immune response in Arabidopsis thaliana.",J Liu 2021,2021,2 genes,Liu-2021-Nep1-like Proteins from Valsa mali Di,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19324,PHI:11895,,no data found,,,,,,VmNLP2,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,necrosis and ethylene-inducing peptide 1(Nep1)-like protein,,,,reduced virulence,,,,,,,,wild type,,no,KCl; sorbitol; SDS; Congo red,KCl: CHEBI:32588; sorbitol: CHEBI:30911; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34682251,PubMed,10.3390/jof7100830,J Fungi (Basel). 2021 Oct 4;7(10):830,huanglili@nwsuaf.edu.cn,"VmNLP2 but not VmNLP1 induced cell death when transiently expressed in Nicotiana benthamiana. The peptide among VmNLP2, called nlp25 (VmNLP2), triggered strong immune response in Arabidopsis thaliana.",J Liu 2021,2021,2 genes,Liu-2021-Nep1-like Proteins from Valsa mali Di,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19325,PHI:11895,,no data found,,,,,,VmNLP2,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,necrosis and ethylene-inducing peptide 1(Nep1)-like protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,KCl; sorbitol; SDS; Congo red,KCl: CHEBI:32588; sorbitol: CHEBI:30911; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34682251,PubMed,10.3390/jof7100830,J Fungi (Basel). 2021 Oct 4;7(10):830,huanglili@nwsuaf.edu.cn,"VmNLP2 but not VmNLP1 induced cell death when transiently expressed in Nicotiana benthamiana. The peptide among VmNLP2, called nlp25 (VmNLP2), triggered strong immune response in Arabidopsis thaliana.",J Liu 2021,2021,2 genes,Liu-2021-Nep1-like Proteins from Valsa mali Di,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19326,PHI:11895,,no data found,,,,,,VmNLP2,VmNLP2Y137H,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,twig; leaf,necrosis and ethylene-inducing peptide 1(Nep1)-like protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,KCl; sorbitol; SDS; Congo red,KCl: CHEBI:32588; sorbitol: CHEBI:30911; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene mutation,,,YVS,34682251,PubMed,10.3390/jof7100830,J Fungi (Basel). 2021 Oct 4;7(10):830,huanglili@nwsuaf.edu.cn,"VmNLP2 but not VmNLP1 induced cell death when transiently expressed in Nicotiana benthamiana. The peptide among VmNLP2, called nlp25 (VmNLP2), triggered strong immune response in Arabidopsis thaliana.",J Liu 2021,2021,2 genes,Liu-2021-Nep1-like Proteins from Valsa mali Di,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19327,PHI:11896,UniProt,G5EHQ2,GenBank,EHA46625,,,70-15,OPR1 (MGG_10583),chromosome 7,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,12-oxophytodienoate reductase,,,jasmonic acid biosynthesis,reduced virulence,,yes,yes,,,reduced; aberrant,,reduced,,no,phenidone,phenidone CAS no.: CAS:92-43-3,,,,,gene deletion: full; gene complementation,,,YVS,34575731,PubMed,10.3390/jof7090693,J Fungi (Basel). 2021 Aug 26;7(9):693,naweed@tll.org.sg,"Loss of 12-Oxo-phytodienoic acid (OPDA) reductase and/or consequent reduction of jasmonate biosynthesis, prolonged germ tube growth and caused delayed initiation and improper development of infection structures in M.oryzae, reminiscent of phenotypic defects upon impaired cyclic AMP (cAMP) signaling.",Y Liu 2021,2021,1 gene,Liu-2021-Fungal Jasmonate as a Novel Morphogen,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19328,PHI:11897,UniProt,P0DKX7,GenBank,CAE41066,,,Tohama I,cyaA,,,,,,,520,Bordetella pertussis,257313,Tohama I,pertussis,rodents,10090,Mus musculus (related: house mouse),BALB/cByJ,,,trachea,cAMP-elevating adenylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34445770,PubMed,10.3390/ijms22169064,Int J Mol Sci. 2021 Aug 23;22(16):9064,osicka@biomed.cas.cz,PT– toxoid-producing B. pertussis mutant secreting the active CyaA toxin elicited a comparable mucin production as infection of epithelial cell layers or tracheal epithelia of infected mice by the wild-type B. pertussis secreting both PT and CyaA toxins.,A Malandra 2021,2021,2 genes,Malandra-2021-Bordetella Adenylate Cyclase Tox,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19329,PHI:11898,,no data found,,,,,,pertussis toxin,,,,,,,520,Bordetella pertussis,257313,Tohama I,pertussis,rodents,10090,Mus musculus (related: house mouse),BALB/cByJ,,,trachea,pertussis (PT) toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34445770,PubMed,10.3390/ijms22169064,Int J Mol Sci. 2021 Aug 23;22(16):9064,osicka@biomed.cas.cz,B. pertussis mutant strain secreting only active PT and producing the enzymatically inactive CyaA-AC– toxoid failed to trigger any important mucus production in infected epithelial cell layers in vitro or in vivo in the tracheal epithelia of intranasally infected mice.,A Malandra 2021,2021,2 genes,Malandra-2021-Bordetella Adenylate Cyclase Tox,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19330,PHI:11897,UniProt,P0DKX7,GenBank,CAE41066,,,Tohama I,cyaA,,,,,,,520,Bordetella pertussis,257313,Tohama I,pertussis,primates,9606,Homo sapiens (related: human),VA10 cell line,,,bronchial epithelial cell line,cAMP-elevating adenylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34445770,PubMed,10.3390/ijms22169064,Int J Mol Sci. 2021 Aug 23;22(16):9064,osicka@biomed.cas.cz,PT– toxoid-producing B. pertussis mutant secreting the active CyaA toxin elicited a comparable mucin production as infection of epithelial cell layers or tracheal epithelia of infected mice by the wild-type B. pertussis secreting both PT and CyaA toxins.,A Malandra 2021,2021,2 genes,Malandra-2021-Bordetella Adenylate Cyclase Tox,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19331,PHI:11898,,no data found,,,,,,pertussis toxin,,,,,,,520,Bordetella pertussis,257313,Tohama I,pertussis,primates,9606,Homo sapiens (related: human),VA10 cell line,,,bronchial epithelial cell line,pertussis (PT) toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34445770,PubMed,10.3390/ijms22169064,Int J Mol Sci. 2021 Aug 23;22(16):9064,osicka@biomed.cas.cz,B. pertussis mutant strain secreting only active PT and producing the enzymatically inactive CyaA-AC– toxoid failed to trigger any important mucus production in infected epithelial cell layers in vitro or in vivo in the tracheal epithelia of intranasally infected mice.,A Malandra 2021,2021,2 genes,Malandra-2021-Bordetella Adenylate Cyclase Tox,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19332,PHI:11899,UniProt,P0DUD0,GenBank,AAT28340,,,YP126,yopJ,F177L; C172A (ksgA- background),,,,,,633,Yersinia pseudotuberculosis,,,zoonotic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,serine/threonine-protein acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34543120,PubMed,10.1128/IAI.00430-21,Infect Immun. 2021 Nov 16;89(12):e0043021,Ralph.Isberg@Tufts.edu,KsgA- strains lacking functional YopJ failed to kill macrophages but actually regained virulence in animals.,C A Mares 2021,2021,1 gene,Mares-2021-Heightened Virulence of Yersinia Is,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19333,PHI:11899,UniProt,P0DUD0,GenBank,AAT28340,,,YP126,yopJ,ksgA- background,,,,,,633,Yersinia pseudotuberculosis,,,zoonotic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,serine/threonine-protein acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34543120,PubMed,10.1128/IAI.00430-21,Infect Immun. 2021 Nov 16;89(12):e0043021,Ralph.Isberg@Tufts.edu,KsgA- strains lacking functional YopJ failed to kill macrophages but actually regained virulence in animals.,C A Mares 2021,2021,1 gene,Mares-2021-Heightened Virulence of Yersinia Is,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19334,PHI:11899,UniProt,P0DUD0,GenBank,AAT28340,,,YP126,yopJ,ksgA- background,,,,,,633,Yersinia pseudotuberculosis,,,zoonotic infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,serine/threonine-protein acetyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34543120,PubMed,10.1128/IAI.00430-21,Infect Immun. 2021 Nov 16;89(12):e0043021,Ralph.Isberg@Tufts.edu,KsgA- strains lacking functional YopJ failed to kill macrophages but actually regained virulence in animals.,C A Mares 2021,2021,1 gene,Mares-2021-Heightened Virulence of Yersinia Is,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19335,PHI:11900,,no data found,,,,,,MakA,,,,,,,562,Escherichia coli,,,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cytolytic toxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,34799450,PubMed,10.1073/pnas.2111418118,Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2111418118,sun.nyunt.wai@umu.se,Expression of MakA/B/E in Escherichia coli resulted in toxicity toward Caenorhabditis elegans.,A Nadeem 2021,2021,3 genes,Nadeem-2021-A tripartite cytolytic toxin forme,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19336,PHI:11901,UniProt,Q9KL65,GenBank,AAF96780,,,N16961,MakB,,,,,,,562,Escherichia coli,,,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cytolytic toxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,34799450,PubMed,10.1073/pnas.2111418118,Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2111418118,sun.nyunt.wai@umu.se,Expression of MakA/B/E in Escherichia coli resulted in toxicity toward Caenorhabditis elegans.,A Nadeem 2021,2021,3 genes,Nadeem-2021-A tripartite cytolytic toxin forme,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19337,PHI:11902,,no data found,,,,,,MakE,,,,,,,562,Escherichia coli,,,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,cytolytic toxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: heterologous expression,,,YVS,34799450,PubMed,10.1073/pnas.2111418118,Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2111418118,sun.nyunt.wai@umu.se,Expression of MakA/B/E in Escherichia coli resulted in toxicity toward Caenorhabditis elegans.,A Nadeem 2021,2021,3 genes,Nadeem-2021-A tripartite cytolytic toxin forme,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19338,PHI:11900,,no data found,,,,,,MakA,,,,,,,666,Vibrio cholerae,,serotype O1 biovar El Tor strain A1552,cholera,primates,9606,Homo sapiens (related: human),,,,erythrocyte,cytolytic toxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34799450,PubMed,10.1073/pnas.2111418118,Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2111418118,sun.nyunt.wai@umu.se,"None of the Mak proteins alone or in pairwise combinations were cytolytic, but an equimolar mixture of MakA, MakB, and MakE acted as a tripartite cytolytic toxin invitro, causing lysis of erythrocytes and cytotoxicity on cultured human colon carcinoma cells.",A Nadeem 2021,2021,3 genes,Nadeem-2021-A tripartite cytolytic toxin forme,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19339,PHI:11901,UniProt,Q9KL65,GenBank,AAF96780,,,N16961,MakB,,,,,,,666,Vibrio cholerae,,serotype O1 biovar El Tor strain A1552,cholera,primates,9606,Homo sapiens (related: human),,,,erythrocyte,cytolytic toxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34799450,PubMed,10.1073/pnas.2111418118,Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2111418118,sun.nyunt.wai@umu.se,"None of the Mak proteins alone or in pairwise combinations were cytolytic, but an equimolar mixture of MakA, MakB, and MakE acted as a tripartite cytolytic toxin invitro, causing lysis of erythrocytes and cytotoxicity on cultured human colon carcinoma cells.",A Nadeem 2021,2021,3 genes,Nadeem-2021-A tripartite cytolytic toxin forme,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19340,PHI:11902,,no data found,,,,,,MakE,,,,,,,666,Vibrio cholerae,,serotype O1 biovar El Tor strain A1552,cholera,primates,9606,Homo sapiens (related: human),,,,erythrocyte,cytolytic toxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34799450,PubMed,10.1073/pnas.2111418118,Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2111418118,sun.nyunt.wai@umu.se,"None of the Mak proteins alone or in pairwise combinations were cytolytic, but an equimolar mixture of MakA, MakB, and MakE acted as a tripartite cytolytic toxin invitro, causing lysis of erythrocytes and cytotoxicity on cultured human colon carcinoma cells.",A Nadeem 2021,2021,3 genes,Nadeem-2021-A tripartite cytolytic toxin forme,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19341,PHI:11900,,no data found,,,,,,MakA,,,,,,,666,Vibrio cholerae,,serotype O1 biovar El Tor strain A1552,cholera,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,cytolytic toxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34799450,PubMed,10.1073/pnas.2111418118,Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2111418118,sun.nyunt.wai@umu.se,"None of the Mak proteins alone or in pairwise combinations were cytolytic, but an equimolar mixture of MakA, MakB, and MakE acted as a tripartite cytolytic toxin invitro, causing lysis of erythrocytes and cytotoxicity on cultured human colon carcinoma cells.",A Nadeem 2021,2021,3 genes,Nadeem-2021-A tripartite cytolytic toxin forme,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19342,PHI:11901,UniProt,Q9KL65,GenBank,AAF96780,,,N16961,MakB,,,,,,,666,Vibrio cholerae,,serotype O1 biovar El Tor strain A1552,cholera,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,cytolytic toxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34799450,PubMed,10.1073/pnas.2111418118,Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2111418118,sun.nyunt.wai@umu.se,"None of the Mak proteins alone or in pairwise combinations were cytolytic, but an equimolar mixture of MakA, MakB, and MakE acted as a tripartite cytolytic toxin invitro, causing lysis of erythrocytes and cytotoxicity on cultured human colon carcinoma cells.",A Nadeem 2021,2021,3 genes,Nadeem-2021-A tripartite cytolytic toxin forme,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19343,PHI:11902,,no data found,,,,,,MakE,,,,,,,666,Vibrio cholerae,,serotype O1 biovar El Tor strain A1552,cholera,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,cytolytic toxin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34799450,PubMed,10.1073/pnas.2111418118,Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2111418118,sun.nyunt.wai@umu.se,"None of the Mak proteins alone or in pairwise combinations were cytolytic, but an equimolar mixture of MakA, MakB, and MakE acted as a tripartite cytolytic toxin invitro, causing lysis of erythrocytes and cytotoxicity on cultured human colon carcinoma cells.",A Nadeem 2021,2021,3 genes,Nadeem-2021-A tripartite cytolytic toxin forme,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19344,PHI:11903,UniProt,Q3BYK9,GenBank,CAJ22054,,,85-10,hrcQ,,M211A,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder,,,leaf,sorting platform component,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34721356,PubMed,10.3389/fmicb.2021.752733,Front Microbiol. 2021 Oct 14;12:752733,daniela.buettner@genetik.uni-halle.de,In cis expression of hrcQM211A abolished pathogenicity.,C Otten 2021,2021,1 gene,Otten-2021-The Contribution of the Predicted S,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19345,PHI:11904,UniProt,P13423,GenBank,AAG24447,,,28,pagA,,,,,,,1392,Bacillus anthracis,,34F2,anthrax,moths,7091,Bombyx mori (related: domestic silkworm),,,,hemolymph,protective antigen,,,,reduced virulence,,,,,,,,,,no,ampicillin; doxycycline,ampicillin: CHEBI:28971; doxycycline: CHEBI:50845,,,,,gene deletion: full,,,YVS,34490836,PubMed,10.1080/21505594.2021.1965830,Virulence. 2021 Dec;12(1):2285-2295,atmikapd@czc.hokudai.ac.jp,"B. anthracis mutants with disruption in virulence genes such as pagA, lef, and atxA had attenuated silkworm-killing ability and reduced colonization in silkworm hemolymph.",A Paudel 2021,2021,3 genes,Paudel-2021-Silkworm model for Bacillus anthra,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19346,PHI:11905,UniProt,P15917,GenBank,AAM26117,,,A2012,lef,,,,,,,1392,Bacillus anthracis,,34F2,anthrax,moths,7091,Bombyx mori (related: domestic silkworm),,,,hemolymph,lethal factor,,,,reduced virulence,,,,,,,,,,no,ampicillin; doxycycline,ampicillin: CHEBI:28971; doxycycline: CHEBI:50845,,,,,gene deletion: full,,,YVS,34490836,PubMed,10.1080/21505594.2021.1965830,Virulence. 2021 Dec;12(1):2285-2295,atmikapd@czc.hokudai.ac.jp,"B. anthracis mutants with disruption in virulence genes such as pagA, lef, and atxA had attenuated silkworm-killing ability and reduced colonization in silkworm hemolymph.",A Paudel 2021,2021,3 genes,Paudel-2021-Silkworm model for Bacillus anthra,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19347,PHI:11906,UniProt,Q44636,GenBank,AAA71986,,,UM23-1,atxA,,,,,,,1392,Bacillus anthracis,,34F2,anthrax,moths,7091,Bombyx mori (related: domestic silkworm),,,,hemolymph,global virulence regulator,,,,reduced virulence,,,,,,,,,,no,ampicillin; doxycycline,ampicillin: CHEBI:28971; doxycycline: CHEBI:50845,,,,,gene deletion: full,,,YVS,34490836,PubMed,10.1080/21505594.2021.1965830,Virulence. 2021 Dec;12(1):2285-2295,atmikapd@czc.hokudai.ac.jp,"B. anthracis mutants with disruption in virulence genes such as pagA, lef, and atxA had attenuated silkworm-killing ability and reduced colonization in silkworm hemolymph.",A Paudel 2021,2021,3 genes,Paudel-2021-Silkworm model for Bacillus anthra,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19348,PHI:11907,UniProt,Q8ZEU2,GenBank,CAL20696,,,CO92,znuA,,,,,,PHI:11908; PHI:11909; PHI:11910,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Hjv<-/->,,,spleen; liver; lung,zinc transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,promoter mutation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,ZnuABC and Ybt are redundant Zn acquisition systems important for mammalian infection.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19349,PHI:11908,UniProt,Q66AT8,GenBank,CAH21280,,,IP 32953,znuB,,,,,,PHI:11907; PHI:11909; PHI:11910,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Hjv<-/->,,,spleen; liver; lung,zinc transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,ZnuABC and Ybt are redundant Zn acquisition systems important for mammalian infection.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19350,PHI:11909,UniProt,Q7CIC2,GenBank,CAL20695,,,CO92,znuC,,,,,,PHI:11907; PHI:11908; PHI:11910,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Hjv<-/->,,,spleen; liver; lung,zinc transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,ZnuABC and Ybt are redundant Zn acquisition systems important for mammalian infection.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19351,PHI:11910,UniProt,A0A3N4B635,GenBank,CAL20550,,,CO92,irp2,,,,,,PHI:11907; PHI:11908; PHI:11909,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Hjv<-/->,,,spleen; liver; lung,yersiniabactin biosynthetic protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,ZnuABC and Ybt are redundant Zn acquisition systems important for mammalian infection.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19352,PHI:11910,UniProt,A0A3N4B635,GenBank,CAL20550,,,CO92,irp2,,,,,,,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Hjv<-/->,,,spleen; liver; lung,yersiniabactin biosynthetic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,ZnuABC and Ybt are redundant Zn acquisition systems important for mammalian infection.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19353,PHI:11907,UniProt,Q8ZEU2,GenBank,CAL20696,,,CO92,znuA,,,,,,PHI:11911,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Hjv<-/->,,,spleen; liver; lung,zinc transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,ZnuABC and Ybt are redundant Zn acquisition systems important for mammalian infection.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19354,PHI:11911,UniProt,Q8CL21,GenBank,AAS61888,,,91001,ybtX,,,,,,PHI:11907,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,rodents,10090,Mus musculus (related: house mouse),Hjv<-/->,,,spleen; liver; lung,"inner membrane protein, membrane permease",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,ZnuABC and Ybt are redundant Zn acquisition systems important for mammalian infection.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19355,PHI:11907,UniProt,Q8ZEU2,GenBank,CAL20696,,,CO92,znuA,,,,,,PHI:11908; PHI:11909,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,fleas,163159,Xenopsylla cheopis (related: Oriental rat flea),,,,,zinc transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,promoter mutation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,Y. pestis colonization of the flea vector required ZnuABC and Ybt Zn acquisition systems.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19356,PHI:11908,UniProt,Q66AT8,GenBank,CAH21280,,,IP 32953,znuB,,,,,,PHI:11907; PHI:11909,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,fleas,163159,Xenopsylla cheopis (related: Oriental rat flea),,,,,zinc transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,Y. pestis colonization of the flea vector required ZnuABC and Ybt Zn acquisition systems.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19357,PHI:11909,UniProt,Q7CIC2,GenBank,CAL20695,,,CO92,znuC,,,,,,PHI:11907; PHI:11908,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,fleas,163159,Xenopsylla cheopis (related: Oriental rat flea),,,,,zinc transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,Y. pestis colonization of the flea vector required ZnuABC and Ybt Zn acquisition systems.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19358,PHI:11907,UniProt,Q8ZEU2,GenBank,CAL20696,,,CO92,znuA,,,,,,PHI:11911,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,fleas,163159,Xenopsylla cheopis (related: Oriental rat flea),,,,,zinc transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,Y. pestis colonization of the flea vector required ZnuABC and Ybt Zn acquisition systems.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19359,PHI:11911,UniProt,Q8CL21,GenBank,AAS61888,,,91001,ybtX,,,,,,PHI:11907,632,Yersinia pestis,,glmS-pstS::kanR,pneumonic plague,fleas,163159,Xenopsylla cheopis (related: Oriental rat flea),,,,,"inner membrane protein, membrane permease",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34716262,PubMed,10.1073/pnas.2104073118,Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2104073118,matt.lawrenz@louisville.edu,Y. pestis colonization of the flea vector required ZnuABC and Ybt Zn acquisition systems.,S L Price 2021,2021,5 genes,Price-2021-Yersiniabactin contributes to overc,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19360,PHI:11912,UniProt,P43464,GenBank,CAA83535,,,17-2,aggR,,clone harboring the FRT sequence following the aggR stop codon (strain 042 aggR + FRT3'UTR),,,,,562,Escherichia coli,216592,042,diarrhea,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,transcriptional activator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34785760,PubMed,10.1038/s42003-021-02820-9,Commun Biol. 2021 Nov 16;4(1):1295,ajuarez@ub.edu,The 042 aggR+FRT3'UTR strain showed higher virulence than the wt strain both in vitro and in vivo.,A Prieto 2021,2021,1 gene,Prieto-2021-Modulation of AggR levels reveals,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19361,PHI:11913,UniProt,S8EZU9,GenBank,EPT28906,,,ME49,GRA28 (TGME49_231960),chromosome VIII,,,,,,5811,Toxoplasma gondii,1080348,type I RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,placenta,"omega secalin, putative",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34781732,PubMed,10.1128/mBio.01591-21,mBio. 2021 Nov 16:e0159121,boylej@pitt.edu,Parasites lacking GRA28 were impaired in their ability to disseminate throughout the animal.,E N Rudzki 2021,2021,1 gene,Rudzki-2021-Toxoplasma gondii GRA28 Is Require,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19362,PHI:11913,UniProt,S8EZU9,GenBank,EPT28906,,,ME49,GRA28 (TGME49_231960),chromosome VIII,,,,,,5811,Toxoplasma gondii,508771,ME49,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,brain,"omega secalin, putative",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34781732,PubMed,10.1128/mBio.01591-21,mBio. 2021 Nov 16:e0159121,boylej@pitt.edu,Parasites lacking GRA28 were impaired in their ability to disseminate throughout the animal.,E N Rudzki 2021,2021,1 gene,Rudzki-2021-Toxoplasma gondii GRA28 Is Require,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19363,PHI:11914,UniProt,P81297,GenBank,CAD61962,,,V8-BC10,scpA,,,,,,,1280,Staphylococcus aureus,,JE2,abscess; sepsis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,staphopain A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34473800,PubMed,10.1371/journal.ppat.1009874,PLoS Pathog. 2021 Sep 2;17(9):e1009874,thomas.rudel@biozentrum.uni-wuerzburg.de,"S. aureus cysteine protease staphopain A, but not staphopain B, was involved in cytotoxicity of S. aureus.",K Stelzner 2021,2021,2 genes,Stelzner-2021-Intracellular Staphylococcus aur,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19364,PHI:11915,UniProt,P0C1S6,GenBank,CAD61963,,,V8-BC10,sspB,,,,,,,1280,Staphylococcus aureus,,JE2,abscess; sepsis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,staphopain B,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34473800,PubMed,10.1371/journal.ppat.1009874,PLoS Pathog. 2021 Sep 2;17(9):e1009874,thomas.rudel@biozentrum.uni-wuerzburg.de,"S. aureus cysteine protease staphopain A, but not staphopain B, was involved in cytotoxicity of S. aureus.",K Stelzner 2021,2021,2 genes,Stelzner-2021-Intracellular Staphylococcus aur,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19365,PHI:11914,UniProt,P81297,GenBank,CAD61962,,,V8-BC10,scpA,,,,,,,1280,Staphylococcus aureus,,JE2,abscess; sepsis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,staphopain A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34473800,PubMed,10.1371/journal.ppat.1009874,PLoS Pathog. 2021 Sep 2;17(9):e1009874,thomas.rudel@biozentrum.uni-wuerzburg.de,Inactivation of staphopain A leads to reduced bacterial load in murine lungs.,K Stelzner 2021,2021,2 genes,Stelzner-2021-Intracellular Staphylococcus aur,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19366,PHI:11914,UniProt,P81297,GenBank,CAD61962,,,V8-BC10,scpA,,,,,,,1280,Staphylococcus aureus,,JE2,abscess; sepsis,primates,9606,Homo sapiens (related: human),M-CSF-derived macrophages,,,macrophage,staphopain A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34473800,PubMed,10.1371/journal.ppat.1009874,PLoS Pathog. 2021 Sep 2;17(9):e1009874,thomas.rudel@biozentrum.uni-wuerzburg.de,No difference in cytotoxicity was observed between S. aureus JE2 and JE2 scpA in human macrophages.,K Stelzner 2021,2021,2 genes,Stelzner-2021-Intracellular Staphylococcus aur,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19367,PHI:11914,UniProt,P81297,GenBank,CAD61962,,,V8-BC10,scpA,,,,,,,1280,Staphylococcus aureus,,JE2,abscess; sepsis,primates,9606,Homo sapiens (related: human),,,,leukocyte,staphopain A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34473800,PubMed,10.1371/journal.ppat.1009874,PLoS Pathog. 2021 Sep 2;17(9):e1009874,thomas.rudel@biozentrum.uni-wuerzburg.de,Cytotoxicity measured by effector caspase activation did not reveal differences between JE2and JE2 scpA-infected PMNs.,K Stelzner 2021,2021,2 genes,Stelzner-2021-Intracellular Staphylococcus aur,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19368,PHI:11916,UniProt,P07801,GenBank,AAL20834,,,LT2,cheR,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,chemotaxis protein methyltransferase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34544273,PubMed,10.1128/mBio.02099-21,mBio. 2021 Oct 26;12(5):e0209921,yfyao@sjtu.edu.cn,"The invasion rate increased by about 50%, owing to cheR overexpression.",Y Su 2021,2021,2 genes,Su-2021-Methylation of PhoP by CheR Regulates,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19369,PHI:11917,UniProt,P0DM78,GenBank,AAL20160,,,LT2,phoP,,,,,,PHI:11916,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,virulence transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34544273,PubMed,10.1128/mBio.02099-21,mBio. 2021 Oct 26;12(5):e0209921,yfyao@sjtu.edu.cn,The cheA/phoP double deletion mutant failed to replicate in macrophage cells.,Y Su 2021,2021,2 genes,Su-2021-Methylation of PhoP by CheR Regulates,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19370,PHI:11916,UniProt,P07801,GenBank,AAL20834,,,LT2,cheR,,,,,,PHI:11917,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,chemotaxis protein methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34544273,PubMed,10.1128/mBio.02099-21,mBio. 2021 Oct 26;12(5):e0209921,yfyao@sjtu.edu.cn,The cheA/phoP double deletion mutant failed to replicate in macrophage cells.,Y Su 2021,2021,2 genes,Su-2021-Methylation of PhoP by CheR Regulates,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19371,PHI:11918,UniProt,D2TKE8,GenBank,CBG89718,,,ICC168,Translocated intimin receptor (Tir),,,,,,,67825,Citrobacter rodentium,,ATCC 51459,colitis,rodents,10090,Mus musculus (related: house mouse),ICR,,,colon; liver,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34702763,PubMed,10.4049/immunohorizons.2100087,Immunohorizons. 2021 Oct 26;5(10):870-883,takahashi@gifu-pu.ac.jp,Ab responses against virulence factors were selectively abrogated in mice infected With the C-terminal truncated mutants.,K Takahashi 2021,2021,1 gene,Takahashi-2021-Intimate Adhesion Is Essential,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19372,PHI:11918,UniProt,D2TKE8,GenBank,CBG89718,,,ICC168,Translocated intimin receptor (Tir),,C-terminal truncated Tir (Tir-M strain lacking 412-547 aa of Tir),,,,,67825,Citrobacter rodentium,,ATCC 51459,colitis,rodents,10090,Mus musculus (related: house mouse),ICR,,,colon; liver,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34702763,PubMed,10.4049/immunohorizons.2100087,Immunohorizons. 2021 Oct 26;5(10):870-883,takahashi@gifu-pu.ac.jp,Ab responses against virulence factors were selectively abrogated in mice infected With the C-terminal truncated mutants.,K Takahashi 2021,2021,1 gene,Takahashi-2021-Intimate Adhesion Is Essential,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19373,PHI:11918,UniProt,D2TKE8,GenBank,CBG89718,,,ICC168,Translocated intimin receptor (Tir),,C-terminal truncated Tir (Tir-N strain lacking 172-547 aa of Tir),,,,,67825,Citrobacter rodentium,,ATCC 51459,colitis,rodents,10090,Mus musculus (related: house mouse),ICR,,,colon; liver,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34702763,PubMed,10.4049/immunohorizons.2100087,Immunohorizons. 2021 Oct 26;5(10):870-883,takahashi@gifu-pu.ac.jp,Ab responses against virulence factors were selectively abrogated in mice infected With the C-terminal truncated mutants.,K Takahashi 2021,2021,1 gene,Takahashi-2021-Intimate Adhesion Is Essential,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19374,PHI:11918,UniProt,D2TKE8,GenBank,CBG89718,,,ICC168,Translocated intimin receptor (Tir),,,,,,,67825,Citrobacter rodentium,,ATCC 51459,colitis,rodents,10090,Mus musculus (related: house mouse),CMT93 cell line,,,CMT-93 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34702763,PubMed,10.4049/immunohorizons.2100087,Immunohorizons. 2021 Oct 26;5(10):870-883,takahashi@gifu-pu.ac.jp,Ab responses against virulence factors were selectively abrogated in mice infected With the C-terminal truncated mutants.,K Takahashi 2021,2021,1 gene,Takahashi-2021-Intimate Adhesion Is Essential,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19375,PHI:11918,UniProt,D2TKE8,GenBank,CBG89718,,,ICC168,Translocated intimin receptor (Tir),,C-terminal truncated Tir (Tir-M strain lacking 412-547 aa of Tir),,,,,67825,Citrobacter rodentium,,ATCC 51459,colitis,rodents,10090,Mus musculus (related: house mouse),CMT93 cell line,,,CMT-93 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34702763,PubMed,10.4049/immunohorizons.2100087,Immunohorizons. 2021 Oct 26;5(10):870-883,takahashi@gifu-pu.ac.jp,Ab responses against virulence factors were selectively abrogated in mice infected With the C-terminal truncated mutants.,K Takahashi 2021,2021,1 gene,Takahashi-2021-Intimate Adhesion Is Essential,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19376,PHI:11918,UniProt,D2TKE8,GenBank,CBG89718,,,ICC168,Translocated intimin receptor (Tir),,C-terminal truncated Tir (Tir-N strain lacking 172-547 aa of Tir),,,,,67825,Citrobacter rodentium,,ATCC 51459,colitis,rodents,10090,Mus musculus (related: house mouse),CMT93 cell line,,,CMT-93 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34702763,PubMed,10.4049/immunohorizons.2100087,Immunohorizons. 2021 Oct 26;5(10):870-883,takahashi@gifu-pu.ac.jp,Ab responses against virulence factors were selectively abrogated in mice infected With the C-terminal truncated mutants.,K Takahashi 2021,2021,1 gene,Takahashi-2021-Intimate Adhesion Is Essential,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19377,PHI:11919,UniProt,P95421,GenBank,CAA67866,,,PAO1,mexE,,,,,,PHI:11920,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,efflux pump membrane transporter,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34680745,PubMed,10.3390/antibiotics10101164,Antibiotics (Basel). 2021 Sep 25;10(10):1164,Peter.Jorth@cshs.org,"Mutations of the mexEF efflux pump system increased swarming, rhamnolipid production, and lethality in a mouse infection model, while mutations in mexR increased virulence during an acute murine lung infection without affecting swarming or rhamnolipid gene expression.",M Vaillancourt 2021,2021,5 genes,Vaillancourt-2021-Pseudomonas aeruginosa mexR,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19378,PHI:11920,UniProt,P95422,GenBank,CAA67864,,,PAO1,mexF,,,,,,PHI:11919,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,efflux pump membrane transporter,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34680745,PubMed,10.3390/antibiotics10101164,Antibiotics (Basel). 2021 Sep 25;10(10):1164,Peter.Jorth@cshs.org,"Mutations of the mexEF efflux pump system increased swarming, rhamnolipid production, and lethality in a mouse infection model, while mutations in mexR increased virulence during an acute murine lung infection without affecting swarming or rhamnolipid gene expression.",M Vaillancourt 2021,2021,5 genes,Vaillancourt-2021-Pseudomonas aeruginosa mexR,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19379,PHI:11921,UniProt,P52003,GenBank,AAA69479,,,PAO,mexR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,multidrug resistance operon repressor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34680745,PubMed,10.3390/antibiotics10101164,Antibiotics (Basel). 2021 Sep 25;10(10):1164,Peter.Jorth@cshs.org,"Mutations of the mexEF efflux pump system increased swarming, rhamnolipid production, and lethality in a mouse infection model, while mutations in mexR increased virulence during an acute murine lung infection without affecting swarming or rhamnolipid gene expression.",M Vaillancourt 2021,2021,5 genes,Vaillancourt-2021-Pseudomonas aeruginosa mexR,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19380,PHI:11922,UniProt,P52477,GenBank,AAA74436,,,CD10,mexA,,,,,,PHI:11923,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,multidrug resistance protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34680745,PubMed,10.3390/antibiotics10101164,Antibiotics (Basel). 2021 Sep 25;10(10):1164,Peter.Jorth@cshs.org,"Mutations of the mexEF efflux pump system increased swarming, rhamnolipid production, and lethality in a mouse infection model, while mutations in mexR increased virulence during an acute murine lung infection without affecting swarming or rhamnolipid gene expression.",M Vaillancourt 2021,2021,5 genes,Vaillancourt-2021-Pseudomonas aeruginosa mexR,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19381,PHI:11923,UniProt,P52002,GenBank,AAA74437,,,CD10,mexB,,,,,,PHI:11922,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,multidrug resistance protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34680745,PubMed,10.3390/antibiotics10101164,Antibiotics (Basel). 2021 Sep 25;10(10):1164,Peter.Jorth@cshs.org,"Mutations of the mexEF efflux pump system increased swarming, rhamnolipid production, and lethality in a mouse infection model, while mutations in mexR increased virulence during an acute murine lung infection without affecting swarming or rhamnolipid gene expression.",M Vaillancourt 2021,2021,5 genes,Vaillancourt-2021-Pseudomonas aeruginosa mexR,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19382,PHI:11924,UniProt,G2X0L1,GenBank,EGY22352,,,VdLs.17,xyn1 (VDAG_03790),chromosome 3,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,xylanase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34618145,PubMed,10.1093/plphys/kiab274,Plant Physiol. 2021 Sep 4;187(1):409-429,zhangdandan@caas.cn,Characterizing gene deletion mutants revealed that only V. dahliae xylanase 4 (VdXyn4) degraded the plant cell wall and contributed to the virulence of V. dahliae.,D Wang 2021,2021,5 genes,Wang-2021-Cytotoxic function of xylanase VdXyn,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19383,PHI:11925,UniProt,A0A6G1NPY9,GenBank,KAF3355309.1,,,,xyn2,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,xylanase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34618145,PubMed,10.1093/plphys/kiab274,Plant Physiol. 2021 Sep 4;187(1):409-429,zhangdandan@caas.cn,Characterizing gene deletion mutants revealed that only V. dahliae xylanase 4 (VdXyn4) degraded the plant cell wall and contributed to the virulence of V. dahliae.,D Wang 2021,2021,5 genes,Wang-2021-Cytotoxic function of xylanase VdXyn,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19384,PHI:11926,UniProt,A0A6G1P7N1,GenBank,KAF3361332.1,,,,xyn3,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,xylanase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34618145,PubMed,10.1093/plphys/kiab274,Plant Physiol. 2021 Sep 4;187(1):409-429,zhangdandan@caas.cn,Characterizing gene deletion mutants revealed that only V. dahliae xylanase 4 (VdXyn4) degraded the plant cell wall and contributed to the virulence of V. dahliae.,D Wang 2021,2021,5 genes,Wang-2021-Cytotoxic function of xylanase VdXyn,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19385,PHI:11927,UniProt,A0A6G1NQY1,GenBank,KAF3355673.1,,,,xyn4,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,xylanase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34618145,PubMed,10.1093/plphys/kiab274,Plant Physiol. 2021 Sep 4;187(1):409-429,zhangdandan@caas.cn,Characterizing gene deletion mutants revealed that only V. dahliae xylanase 4 (VdXyn4) degraded the plant cell wall and contributed to the virulence of V. dahliae.,D Wang 2021,2021,5 genes,Wang-2021-Cytotoxic function of xylanase VdXyn,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19386,PHI:11928,UniProt,A0A6G1NQX7,GenBank,KAF3355674.1,,,,xyn5,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,xylanase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34618145,PubMed,10.1093/plphys/kiab274,Plant Physiol. 2021 Sep 4;187(1):409-429,zhangdandan@caas.cn,Characterizing gene deletion mutants revealed that only V. dahliae xylanase 4 (VdXyn4) degraded the plant cell wall and contributed to the virulence of V. dahliae.,D Wang 2021,2021,5 genes,Wang-2021-Cytotoxic function of xylanase VdXyn,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19387,PHI:11927,UniProt,A0A6G1NQY1,GenBank,KAF3355673.1,,,,xyn4,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,xylanase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,34618145,PubMed,10.1093/plphys/kiab274,Plant Physiol. 2021 Sep 4;187(1):409-429,zhangdandan@caas.cn,Transient expression of VdXyn4 in N. benthamiana induced cell death in the vein tissue by virtue of its cytotoxic activity that was dependent on the xylanase activity of VdXyn4.,D Wang 2021,2021,5 genes,Wang-2021-Cytotoxic function of xylanase VdXyn,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19388,PHI:11929,UniProt,A0A385CIT3,GenBank,AXQ39868,,,HB1,mat1-1-1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,mating-type protein,,,,unaffected pathogenicity,,no,no,,,wild type,reduced,wild type,wild type,no,calcofluor white; Congo red; H2O2; methyl viologen,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,34682279,PubMed,10.3390/jof7100858,J Fungi (Basel). 2021 Oct 13;7(10):858,fuchenglin@zju.edu.c,"MAT loci and MAT genes were dispensable for vegetative growth, asexual conidiation or pathogenicity of the fungus.",J Y Wang 2021,2021,5 genes,Wang-2021-MAT Loci Play Crucial Roles in Sexua,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19389,PHI:11930,UniProt,Q86Z80,GenBank,BAC65084,,,Hoku-1,mat1-1-2,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,mating-type protein,,,,unaffected pathogenicity,,no,no,,,wild type,reduced,wild type,wild type,no,calcofluor white; Congo red; H2O2; methyl viologen,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,34682279,PubMed,10.3390/jof7100858,J Fungi (Basel). 2021 Oct 13;7(10):858,fuchenglin@zju.edu.c,"MAT loci and MAT genes were dispensable for vegetative growth, asexual conidiation or pathogenicity of the fungus.",J Y Wang 2021,2021,5 genes,Wang-2021-MAT Loci Play Crucial Roles in Sexua,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19390,PHI:11931,,no data found,,,,,,mat1-1-3,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,mating-type protein,,,,unaffected pathogenicity,,no,no,,,wild type,reduced,wild type,wild type,no,calcofluor white; Congo red; H2O2; methyl viologen,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,34682279,PubMed,10.3390/jof7100858,J Fungi (Basel). 2021 Oct 13;7(10):858,fuchenglin@zju.edu.c,"MAT loci and MAT genes were dispensable for vegetative growth, asexual conidiation or pathogenicity of the fungus.",J Y Wang 2021,2021,5 genes,Wang-2021-MAT Loci Play Crucial Roles in Sexua,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19391,PHI:11932,UniProt,A0A385CIQ8,GenBank,AXQ39867,,,SD1,mat1-2-1,,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,mating-type protein,,,,unaffected pathogenicity,,no,no,,,wild type,reduced,wild type,wild type,no,calcofluor white; Congo red; H2O2; methyl viologen,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,34682279,PubMed,10.3390/jof7100858,J Fungi (Basel). 2021 Oct 13;7(10):858,fuchenglin@zju.edu.c,"MAT loci and MAT genes were dispensable for vegetative growth, asexual conidiation or pathogenicity of the fungus.",J Y Wang 2021,2021,5 genes,Wang-2021-MAT Loci Play Crucial Roles in Sexua,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19392,PHI:11933,,no data found,,,,,,mat1-2-2,,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,mating-type protein,,,,unaffected pathogenicity,,no,no,,,wild type,reduced,wild type,wild type,no,calcofluor white; Congo red; H2O2; methyl viologen,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; methyl viologen: CHEBI:28786,,,,,gene deletion: full; gene complementation,,,YVS,34682279,PubMed,10.3390/jof7100858,J Fungi (Basel). 2021 Oct 13;7(10):858,fuchenglin@zju.edu.c,"MAT loci and MAT genes were dispensable for vegetative growth, asexual conidiation or pathogenicity of the fungus.",J Y Wang 2021,2021,5 genes,Wang-2021-MAT Loci Play Crucial Roles in Sexua,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19393,PHI:11934,,no data found,,,,,,PeRmtA,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3750,Malus domestica (related: apple),,,,fruit,protein arginine methyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19394,PHI:11935,,no data found,,,,,,PeRmtB,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3750,Malus domestica (related: apple),,,,fruit,protein arginine methyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,reduced,wild type,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19395,PHI:11936,,no data found,,,,,,PeRmtC,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3750,Malus domestica (related: apple),,,,fruit,protein arginine methyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19396,PHI:11937,UniProt,A0A0A2L1N2,GenBank,KGO52424,,,MD-8,PeRmt2,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3750,Malus domestica (related: apple),,,,fruit,arginine N-methyltransferase 2,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19397,PHI:11934,,no data found,,,,,,PeRmtA,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,protein arginine methyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19398,PHI:11935,,no data found,,,,,,PeRmtB,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,protein arginine methyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,reduced,wild type,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19399,PHI:11936,,no data found,,,,,,PeRmtC,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,protein arginine methyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19400,PHI:11937,UniProt,A0A0A2L1N2,GenBank,KGO52424,,,MD-8,PeRmt2,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,arginine N-methyltransferase 2,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19401,PHI:11934,,no data found,,,,,,PeRmtA,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3760,Prunus persica (related: peach),var. nucipersica (nectarine),,,fruit,protein arginine methyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19402,PHI:11935,,no data found,,,,,,PeRmtB,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3760,Prunus persica (related: peach),var. nucipersica (nectarine),,,fruit,protein arginine methyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,reduced,wild type,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19403,PHI:11936,,no data found,,,,,,PeRmtC,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3760,Prunus persica (related: peach),var. nucipersica (nectarine),,,fruit,protein arginine methyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19404,PHI:11937,UniProt,A0A0A2L1N2,GenBank,KGO52424,,,MD-8,PeRmt2,,,,,,,27334,Penicillium expansum,1407458,T01,fruit decay,eudicots,3760,Prunus persica (related: peach),var. nucipersica (nectarine),,,fruit,arginine N-methyltransferase 2,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,NaCl; Congo red; H2O2; SDS,NaCl: CHEBI:26710; Congo red: CHEBI:34653; H2O2: CHEBI:16240; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,34682229,PubMed,10.3390/jof7100807,J Fungi (Basel). 2021 Sep 27;7(10):807,tsp@ibcas.ac.cn,"The single deletion of PeRmtA, PeRmtB, or PeRmt2 had minor or no impact on the P. expansum phenotype while deletion of PeRmtC resulted in decreased conidiation, delayed conidial germination, impaired pathogenicity and pigment biosynthesis, and altered tolerance to environmental stresses.",X Xu 2021,2021,4 genes,Xu-2021-Arginine Methyltransferase PeRmtC Regu,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19405,PHI:11938,,no data found,,,,,,tssS,,,,,,,633,Yersinia pseudotuberculosis,,YP216,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon; cecum; liver; spleen; peritoneal macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34625471,PubMed,10.1073/pnas.2103526118,Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2103526118,xihuishen@nwsuaf.edu.cn,"The mutant strain lacking TssS (ΔtssS) showed substantially reduced virulence but induced a significantly stronger host innate immune response, indicating an antagonistic role of this effector in host antimicrobial immunity.",L Zhu 2021,2021,1 gene,Zhu-2021-T6SS translocates a micropeptide to s,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19406,PHI:11938,,no data found,,,,,,tssS,,,,,,,633,Yersinia pseudotuberculosis,,YP216,gut-associated disease; diarrhea; enteritis; colitis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34625471,PubMed,10.1073/pnas.2103526118,Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2103526118,xihuishen@nwsuaf.edu.cn,"The mutant strain lacking TssS (ΔtssS) showed substantially reduced virulence but induced a significantly stronger host innate immune response, indicating an antagonistic role of this effector in host antimicrobial immunity.",L Zhu 2021,2021,1 gene,Zhu-2021-T6SS translocates a micropeptide to s,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19407,PHI:11939,,no data found,,,,,,mavR,,,,,,,562,Escherichia coli,,86-24,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,cecum; colon,pathogen-specific sRNA,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34591974,PubMed,10.1093/nar/gkab863,Nucleic Acids Res. 2021 Nov 8;49(19):10988-11004,melissakendall@virginia.edu,Deletion of mavR resulted in significant (~10 to 100 fold) attenuation in colonization of the mammalian intestine.,A B Sauder 2021,2021,1 gene,Sauder-2021-A pathogen-specific sRNA influence,BATCH_109C,2022-01-01,MC,,,,,,,,,,,,,
,,Record 19408,PHI:11940,UniProt,I1RII8,GenBank,CEF78463,,,PH-1,FGSG_03624,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Svevo,,,spikelet,xylanase,,,,reduced virulence,,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34639149,PubMed,10.3390/ijms221910811,Int J Mol Sci. 2021 Oct 6;22(19):10811,luca.sella@unipd.it,Spray treatment of wheat spikes with Xyl conferred increased resistance to FHB and decreased fungal biomass in kernels.,S Tundo 2021,2021,1 gene,Tundo-2021-The Fusarium graminearum FGSG_03624,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19409,PHI:11941,UniProt,E7PT28,GenBank,EGH13406,,,race 4,algU (VTO41),,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,RNA polymerase sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19410,PHI:11942,UniProt,no data found,GenBank,,,,,VTB8,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19411,PHI:11943,UniProt,no data found,GenBank,,,,,VTC23,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19412,PHI:11944,UniProt,no data found,GenBank,,,,,VTD16,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19413,PHI:11945,UniProt,no data found,GenBank,,,,,VTD28,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19414,PHI:11946,UniProt,no data found,GenBank,,,,,VTD29,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19415,PHI:11947,UniProt,no data found,GenBank,,,,,VTD30,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19416,PHI:11948,UniProt,no data found,GenBank,,,,,VTE13,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19417,PHI:11949,UniProt,no data found,GenBank,,,,,VTE17,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19418,PHI:11950,UniProt,no data found,GenBank,,,,,VTF3,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19419,PHI:11951,UniProt,no data found,GenBank,,,,,VTG22,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19420,PHI:11952,UniProt,no data found,GenBank,,,,,VTG29,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19421,PHI:11953,UniProt,no data found,GenBank,,,,,VTG41,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19422,PHI:11954,UniProt,no data found,GenBank,,,,,VTH39,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19423,PHI:11955,UniProt,no data found,GenBank,,,,,VTI15,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19424,PHI:11956,UniProt,no data found,GenBank,,,,,VTR4,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19425,PHI:11957,UniProt,no data found,GenBank,,,,,VTT14,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19426,PHI:11958,UniProt,no data found,GenBank,,,,,VTT22,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19427,PHI:11959,UniProt,no data found,GenBank,,,,,VTB2,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,type III effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19428,PHI:11960,UniProt,no data found,GenBank,,,,,VTB52,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,heat shock protein 90,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19429,PHI:11961,UniProt,no data found,GenBank,,,,,VTH40,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,MFS transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19430,PHI:11962,UniProt,no data found,GenBank,,,,,VTM22,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19431,PHI:11963,UniProt,no data found,GenBank,,,,,VTO15,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,ABC transporter permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19432,PHI:11964,UniProt,no data found,GenBank,,,,,VTP20,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,DNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19433,PHI:11965,UniProt,no data found,GenBank,,,,,VTE41,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19434,PHI:11966,UniProt,no data found,GenBank,,,,,VTF6,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19435,PHI:11967,UniProt,no data found,GenBank,,,,,VTO37,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19436,PHI:11968,UniProt,no data found,GenBank,,,,,VTT8,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Enrei,,,leaf,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34760389,PubMed,10.7717/peerj.12405,PeerJ. 2021 Oct 29;9:e12405,ishiga.yasuhiro.km@u.tsukuba.ac.jp,Inoculation of soybean leaves with these mutants and the algU mutant showed significantly reduced virulence together with reduced bacterial populations in planta.,V T Nguyen 2021,2021,28 genes,Nguyen-2021-Multiple virulence factors regulat,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19437,PHI:11969,,no data found,,,,,,PKS8-2,,,,,,,1873960,Pseudocercospora fijiensis,,10CR1-24,black sigatoka,monocots,4641,Musa acuminata (related: dwarf banana),cv. Grand Nain,,,leaf,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34705882,PubMed,10.1371/journal.pone.0258981,PLoS One. 2021 Oct 27;16(10):e0258981,margaret_daub@ncsu.edu,Silencing transformants for PKS8-2 and PKS10-2 showed significant reduction in disease symptoms and severity.,E Thomas 2021,2021,2 genes,Thomas-2021-A polyketide synthase gene cluster,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19438,PHI:11970,,no data found,,,,,,PKS10-2,,,,,,,1873960,Pseudocercospora fijiensis,,10CR1-24,black sigatoka,monocots,4641,Musa acuminata (related: dwarf banana),cv. Grand Nain,,,leaf,polyketide synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34705882,PubMed,10.1371/journal.pone.0258981,PLoS One. 2021 Oct 27;16(10):e0258981,margaret_daub@ncsu.edu,Silencing transformants for PKS8-2 and PKS10-2 showed significant reduction in disease symptoms and severity.,E Thomas 2021,2021,2 genes,Thomas-2021-A polyketide synthase gene cluster,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19439,PHI:11971,UniProt,J9VVE4,GenBank,AFR98238,,,H99,CMP1 (CNAG_06000),chromosome 12,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,putative mannoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34724829,PubMed,10.1128/mBio.02313-21,mBio. 2021 Nov 2;12(6):e0231321,cuomo@broadinstitute.org,Loss of CMP1 gene resulted in an attenuated cryptococcal strain in mice lungs and rabbit CSF.,C H Yu 2021,2021,1 gene,Yu-2021-Gene Expression of Diverse Cryptococcu,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19440,PHI:11971,UniProt,J9VVE4,GenBank,AFR98238,,,H99,CMP1 (CNAG_06000),chromosome 12,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,cerebrospinal fluid,putative mannoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34724829,PubMed,10.1128/mBio.02313-21,mBio. 2021 Nov 2;12(6):e0231321,cuomo@broadinstitute.org,Loss of CMP1 gene resulted in an attenuated cryptococcal strain in mice lungs and rabbit CSF.,C H Yu 2021,2021,1 gene,Yu-2021-Gene Expression of Diverse Cryptococcu,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19441,PHI:11972,UniProt,A0A125YY88,GenBank,EPT32247,,,ME49,fabZ (TGME49_321570),chromosome Ib,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,beta-hydroxyacyl-acyl carrier protein dehydratase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,34531837,PubMed,10.3389/fmicb.2021.703059,Front Microbiol. 2021 Aug 31;12:703059,xingquanzhu1@hotmail.com,"RHΔFabZ exhibited reduced virulence for mice compared with RHΔODSCI and RHΔODSCII, as shown by the improved survival rate.",X P Xu 2021,2021,3 genes,Xu-2021-The Role of Type II Fatty Acid Synthes,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19442,PHI:11973,UniProt,S7WL17,GenBank,EPR64923,,,GT1,ODSCI (TGGT1_269400),,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,"oxidoreductase, short chain dehydrogenase/reductase family protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34531837,PubMed,10.3389/fmicb.2021.703059,Front Microbiol. 2021 Aug 31;12:703059,xingquanzhu1@hotmail.com,"RHΔFabZ exhibited reduced virulence for mice compared with RHΔODSCI and RHΔODSCII, as shown by the improved survival rate.",X P Xu 2021,2021,3 genes,Xu-2021-The Role of Type II Fatty Acid Synthes,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19443,PHI:11974,UniProt,A0A125YV82,GenBank,EPR60978,,,GT1,ODSCII (TGGT1_313050),,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,"oxidoreductase, short chain dehydrogenase/reductase family protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34531837,PubMed,10.3389/fmicb.2021.703059,Front Microbiol. 2021 Aug 31;12:703059,xingquanzhu1@hotmail.com,"RHΔFabZ exhibited reduced virulence for mice compared with RHΔODSCI and RHΔODSCII, as shown by the improved survival rate.",X P Xu 2021,2021,3 genes,Xu-2021-The Role of Type II Fatty Acid Synthes,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19444,PHI:11972,UniProt,A0A125YY88,GenBank,EPT32247,,,ME49,fabZ (TGME49_321570),chromosome Ib,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,beta-hydroxyacyl-acyl carrier protein dehydratase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,34531837,PubMed,10.3389/fmicb.2021.703059,Front Microbiol. 2021 Aug 31;12:703059,xingquanzhu1@hotmail.com,"RHΔFabZ exhibited reduced virulence for mice compared with RHΔODSCI and RHΔODSCII, as shown by the improved survival rate.",X P Xu 2021,2021,3 genes,Xu-2021-The Role of Type II Fatty Acid Synthes,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19445,PHI:11973,UniProt,S7WL17,GenBank,EPR64923,,,GT1,ODSCI (TGGT1_269400),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,"oxidoreductase, short chain dehydrogenase/reductase family protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34531837,PubMed,10.3389/fmicb.2021.703059,Front Microbiol. 2021 Aug 31;12:703059,xingquanzhu1@hotmail.com,"RHΔFabZ exhibited reduced virulence for mice compared with RHΔODSCI and RHΔODSCII, as shown by the improved survival rate.",X P Xu 2021,2021,3 genes,Xu-2021-The Role of Type II Fatty Acid Synthes,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19446,PHI:11974,UniProt,A0A125YV82,GenBank,EPR60978,,,GT1,ODSCII (TGGT1_313050),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,"oxidoreductase, short chain dehydrogenase/reductase family protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,34531837,PubMed,10.3389/fmicb.2021.703059,Front Microbiol. 2021 Aug 31;12:703059,xingquanzhu1@hotmail.com,"RHΔFabZ exhibited reduced virulence for mice compared with RHΔODSCI and RHΔODSCII, as shown by the improved survival rate.",X P Xu 2021,2021,3 genes,Xu-2021-The Role of Type II Fatty Acid Synthes,BATCH_109D,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19447,PHI:11975,UniProt,A0A177DDY0,GenBank,OAG17698,,,SRC1lrK2f,TAS1 (CC77DRAFT_941807),,,,,,,5599,Alternaria alternata,,XJaa,brown spot,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,tenuazonic acid (TeA) synthetase 1,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35175146,PubMed,10.1094/MPMI-12-21-0300-R,Mol Plant Microbe Interact. 2022 Feb 17,abwu@sibs.ac.cn,The tenuazonic acid yield of ΔAaTAS1 and ΔAaMFS1 dropped significantly compared with that of the wild-type strain.,F Sun 2022,2022,2 genes,Sun-2022-AaTAS1 and AaMFS1 genes for biosynthe,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19448,PHI:11976,UniProt,A0A177DFV7,GenBank,OAG17699,,,SRC1lrK2f,MFS1 (CC77DRAFT_269024 ),,,,,,,5599,Alternaria alternata,,XJaa,brown spot,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,major facilitator superfamily protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35175146,PubMed,10.1094/MPMI-12-21-0300-R,Mol Plant Microbe Interact. 2022 Feb 17,abwu@sibs.ac.cn,The tenuazonic acid yield of ΔAaTAS1 and ΔAaMFS1 dropped significantly compared with that of the wild-type strain.,F Sun 2022,2022,2 genes,Sun-2022-AaTAS1 and AaMFS1 genes for biosynthe,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19449,PHI:11977,UniProt,F7IWF6,GenBank,AAS10900,,,ATCC 35405,msp,,,,,,,158,Treponema denticola,243275,ATCC 35405,chronic periodontitis,carnivores,9612,Canis lupus (related: gray wolf),subsp. familiaris MDCK cell line,,,MDCK cell,major surface protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35173086,PubMed,10.2209/tdcpublication.2021-0037,Bull Tokyo Dent Coll. 2022 Feb 15,kokubu@tdc.ac.jp,Retardation of cell migration was lower with the Msp-mutant strain than with the wild-type starin.,E Kokubu 2022,2022,2 genes,Kokubu-2022-Effect of Treponema Denticola Infe,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19450,PHI:11978,UniProt,P96091,GenBank,BAA11874,,,ATCC 35405,dentilisin,,,,,,,158,Treponema denticola,243275,ATCC 35405,chronic periodontitis,carnivores,9612,Canis lupus (related: gray wolf),subsp. familiaris MDCK cell line,,,MDCK cell,serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35173086,PubMed,10.2209/tdcpublication.2021-0037,Bull Tokyo Dent Coll. 2022 Feb 15,kokubu@tdc.ac.jp,"The scratched area showed a 100% recovery with the control and dentilisin mutants, but not with the wild-type or Msp mutant strains.",E Kokubu 2022,2022,2 genes,Kokubu-2022-Effect of Treponema Denticola Infe,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19451,PHI:11979,UniProt,G4N0E5,GenBank,EHA52279,,,70-15,Mopcs60 (MGG_06199),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,peroxisomal-CoA synthetase,,,,reduced virulence,,no,no,yes,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35154208,PubMed,10.3389/fpls.2021.811041,Front Plant Sci. 2022 Jan 26;12:811041,hfzhang@njau.edu.cn,"Compared with the wild-type strain Guy11, the ΔMopcs60 mutant exhibited fewer peroxisomes, more lipid droplets, and decreased pathogenicity.",T Zhang 2021,2021,1 gene,Zhang-2021-The Peroxisomal-CoA Synthetase MoPc,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19452,PHI:11979,UniProt,G4N0E5,GenBank,EHA52279,,,70-15,Mopcs60 (MGG_06199),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,peroxisomal-CoA synthetase,,,,reduced virulence,,no,no,yes,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35154208,PubMed,10.3389/fpls.2021.811041,Front Plant Sci. 2022 Jan 26;12:811041,hfzhang@njau.edu.cn,"Compared with the wild-type strain Guy11, the ΔMopcs60 mutant exhibited fewer peroxisomes, more lipid droplets, and decreased pathogenicity.",T Zhang 2021,2021,1 gene,Zhang-2021-The Peroxisomal-CoA Synthetase MoPc,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19453,PHI:11980,UniProt,G1X9C7,GenBank,EGX50159,,,ATCC 24927,AolAtg1 (AOL_s00076g234),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,autophagy-related protein 1,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,H2O2; NaCl; menadione; sorbitol,H2O2: CHEBI:16240; NaCl: CHEBI:26710; menadione: CHEBI:28869; sorbitol: CHEBI:17924,,,,,gene deletion: full,,,YVS,35145926,PubMed,10.3389/fcimb.2021.824407,Front Cell Infect Microbiol. 2022 Jan 25;11:824407,jinkui960@ynu.edu.cn,"Deletion of Aolatg1 caused severe defects in mycelial growth, conidiation, conidial germination, trap formation, and nematode predation.",D Zhou 2021,2021,2 genes,Zhou-2021-Aolatg1 and Aolatg13 Regulate Autoph,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19454,PHI:11981,UniProt,G1XTE5,GenBank,EGX43338,,,ATCC 24927,AolAtg13 (AOL_s00215g74),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,autophagy-related protein 13,,,,unaffected pathogenicity,,,,,,wild type,,reduced,wild type,no,H2O2; NaCl; menadione; sorbitol,H2O2: CHEBI:16240; NaCl: CHEBI:26710; menadione: CHEBI:28869; sorbitol: CHEBI:17924,,,,,gene deletion: full,,,YVS,35145926,PubMed,10.3389/fcimb.2021.824407,Front Cell Infect Microbiol. 2022 Jan 25;11:824407,jinkui960@ynu.edu.cn,"Except for the altered resistance to several chemical stressors, no obvious differences were observed in phenotypic traits between the WT and ΔAolatg13 mutant strains.",D Zhou 2021,2021,2 genes,Zhou-2021-Aolatg1 and Aolatg13 Regulate Autoph,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19455,PHI:11982,UniProt,P21454,GenBank,CAA78760,,,ML R66,spvB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,colon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35110556,PubMed,10.1038/s41420-022-00841-9,Cell Death Discov. 2022 Feb 2;8(1):44,wushuyan@suda.edu.cn,SpvB promoted the pathogenicity of Salmonella and induced colon cell death in vivo.,K Dong 2022,2022,1 gene,Dong-2022-Salmonella pSLT-encoded effector Spv,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19456,PHI:11982,UniProt,P21454,GenBank,CAA78760,,,ML R66,spvB,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35110556,PubMed,10.1038/s41420-022-00841-9,Cell Death Discov. 2022 Feb 2;8(1):44,wushuyan@suda.edu.cn,SpvB promoted the pathogenicity of Salmonella and induced colon cell death in vivo.,K Dong 2022,2022,1 gene,Dong-2022-Salmonella pSLT-encoded effector Spv,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19457,PHI:11983,UniProt,A7L3L3,GenBank,ABS83487,,,SC5314,HAC1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,transcription factor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35108336,PubMed,10.1371/journal.ppat.1010283,PLoS Pathog. 2022 Feb 2;18(2):e1010283,joachim.morschhaeuser@uni-wuerzburg.de,"Both ire1Δ and hac1Δ mutants were avirulent in a mouse model of systemic candidiasis, indicating that an appropriate response to endoplasmic reticulum stress is important for the virulence of C. albicans.",B Ramírez-Zavala 2022,2022,2 genes,Ramírez-Zavala-2022-The protein kinase Ire1 ha,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19458,PHI:11984,UniProt,A0A1D8PE76,GenBank,AOW26437,,,SC5314,IRE1,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,protein kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35108336,PubMed,10.1371/journal.ppat.1010283,PLoS Pathog. 2022 Feb 2;18(2):e1010283,joachim.morschhaeuser@uni-wuerzburg.de,"Both ire1Δ and hac1Δ mutants were avirulent in a mouse model of systemic candidiasis, indicating that an appropriate response to endoplasmic reticulum stress is important for the virulence of C. albicans.",B Ramírez-Zavala 2022,2022,2 genes,Ramírez-Zavala-2022-The protein kinase Ire1 ha,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19459,PHI:11985,UniProt,J9VEP9,GenBank,AFR92822,,,H99,Cdc4 (CNAG_00693),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,F-box protein,,,,loss of pathogenicity,yes,,,,,,reduced,,,no,H2O2; NaCl; KCl; NaNO2; SDS; Congo red; actinomycin D; methyl methanesulfonate,H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; NaNO2: CHEBI:78870; SDS: CHEBI:8984; Congo red: CHEBI:34653; actinomycin D: CHEBI:22218; methyl methanesulfonate: CHEBI:25255,,,,,gene deletion: full,,,YVS,35087766,PubMed,10.3389/fcimb.2021.806465,Front Cell Infect Microbiol. 2022 Jan 11;11:806465,tongbaoliu@swu.edu.cn,Fungal mating assays showed that Cdc4 was essential for fungal sexual reproduction in C. neoformans.,T Wu 2021,2021,1 gene,Wu-2021-Role of F-box Protein Cdc4 in Fungal V,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19460,PHI:11985,UniProt,J9VEP9,GenBank,AFR92822,,,H99,Cdc4 (CNAG_00693),chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; lung; spleen,F-box protein,,,,increased virulence (hypervirulence),yes,,,,,,reduced,,,no,H2O2; NaCl; KCl; NaNO2; SDS; Congo red; actinomycin D; methyl methanesulfonate,H2O2: CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; NaNO2: CHEBI:78870; SDS: CHEBI:8984; Congo red: CHEBI:34653; actinomycin D: CHEBI:22218; methyl methanesulfonate: CHEBI:25255,,,,,altered gene expression / gene regulation: overexpression,,,YVS,35087766,PubMed,10.3389/fcimb.2021.806465,Front Cell Infect Microbiol. 2022 Jan 11;11:806465,tongbaoliu@swu.edu.cn,Fungal mating assays showed that Cdc4 was essential for fungal sexual reproduction in C. neoformans.,T Wu 2021,2021,1 gene,Wu-2021-Role of F-box Protein Cdc4 in Fungal V,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19461,PHI:11986,UniProt,A0A0H3HR34,GenBank,AFI68396,,,1026b,BPM02934 (vgrG2),chromosome 2,,,,,,28450,Burkholderia pseudomallei,,,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver,valine-glycine repeat protein G,,,,reduced virulence,,,,,,,,wild type,,no,amoxicillin; clavulanate; ceftazidime; imipenem; tetracycline; doxycycline; trimethoprim; sulfamethoxazole,amoxicillin: CHEBI:2676; clavulanate: CHEBI:487869; ceftazidime: CHEBI:3508; imipenem: CHEBI:471744; tetracycline: CHEBI:27902; doxycycline: CHEBI:50845; trimethoprim: CHEBI:45924; sulfamethoxazole: CHEBI:9332,,,,,gene deletion: full; gene complementation,,,YVS,35069514,PubMed,10.3389/fmicb.2021.811343,Front Microbiol. 2022 Jan 5;12:811343,shiqiong@cqmu.edu.cn,The deletion of vgrG2 gene significantly led to the decrease in the lethality of BPM and impaired its ability to trigger host immune response.,J Li 2021,2021,1 gene,Li-2021-Characterization of a Type VI Secretio,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19462,PHI:11986,UniProt,A0A0H3HR34,GenBank,AFI68396,,,1026b,BPM02934 (vgrG2),chromosome 2,,,,,,28450,Burkholderia pseudomallei,,,melioidosis,primates,9606,Homo sapiens (related: human),,,,blood,valine-glycine repeat protein G,,,,reduced virulence,,,,,,,,wild type,,no,amoxicillin; clavulanate; ceftazidime; imipenem; tetracycline; doxycycline; trimethoprim; sulfamethoxazole,amoxicillin: CHEBI:2676; clavulanate: CHEBI:487869; ceftazidime: CHEBI:3508; imipenem: CHEBI:471744; tetracycline: CHEBI:27902; doxycycline: CHEBI:50845; trimethoprim: CHEBI:45924; sulfamethoxazole: CHEBI:9332,,,,,gene deletion: full; gene complementation,,,YVS,35069514,PubMed,10.3389/fmicb.2021.811343,Front Microbiol. 2022 Jan 5;12:811343,shiqiong@cqmu.edu.cn,The deletion of vgrG2 gene significantly led to the decrease in the lethality of BPM and impaired its ability to trigger host immune response.,J Li 2021,2021,1 gene,Li-2021-Characterization of a Type VI Secretio,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19463,PHI:11986,UniProt,A0A0H3HR34,GenBank,AFI68396,,,1026b,BPM02934 (vgrG2),chromosome 2,,,,,,28450,Burkholderia pseudomallei,,,melioidosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,valine-glycine repeat protein G,,,,reduced virulence,,,,,,,,wild type,,no,amoxicillin; clavulanate; ceftazidime; imipenem; tetracycline; doxycycline; trimethoprim; sulfamethoxazole,amoxicillin: CHEBI:2676; clavulanate: CHEBI:487869; ceftazidime: CHEBI:3508; imipenem: CHEBI:471744; tetracycline: CHEBI:27902; doxycycline: CHEBI:50845; trimethoprim: CHEBI:45924; sulfamethoxazole: CHEBI:9332,,,,,gene deletion: full; gene complementation,,,YVS,35069514,PubMed,10.3389/fmicb.2021.811343,Front Microbiol. 2022 Jan 5;12:811343,shiqiong@cqmu.edu.cn,The deletion of vgrG2 gene significantly led to the decrease in the lethality of BPM and impaired its ability to trigger host immune response.,J Li 2021,2021,1 gene,Li-2021-Characterization of a Type VI Secretio,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19464,PHI:11987,UniProt,A0A0F6KRN4,GenBank,ALL38039,,,B3R3,slyA,,,,,,,615,Serratia marcescens,,SCQ1,nosocomial infection,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,transcription regulator,,,prodigiosin biosynthesis,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35058908,PubMed,10.3389/fmicb.2021.793202,Front Microbiol. 2022 Jan 4;12:793202,canbl3312@126.com,"The ΔslyA strain loses prodigiosin synthesis capacity, but has a higher cell density, and surprisingly enhances the virulence as an entomopathogen.",T Xiang 2021,2021,1 gene,Xiang-2021-Transcriptomic Analysis Reveals Com,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19465,PHI:11988,UniProt,I1S287,GenBank,SCB64961,,,PH-1,FgRab1 (FGSG_10873),chromosome 3,FgRab1 dominant-negative,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,Rab GTPase,,,,reduced virulence,,,,,,reduced; aberrant,wild type,reduced,,no,,,,,,,gene mutation,,,YVS,35055095,PubMed,10.3390/ijms23020895,Int J Mol Sci. 2022 Jan 14;23(2):895,zhw@mju.edu.cn,Fgrab1DN was dramatically reduced in its ability to cause Fusarium head blight symptoms on wheat heads.,Y Yuan 2022,2022,1 gene,Yuan-2022-The Small GTPase FgRab1 Plays Indisp,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19466,PHI:11989,UniProt,G5EH52,GenBank,EAQ71017,,,70-15,MoALO1 (MGG_02689),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,"putative D-arabinono-1,4-lactone oxidase",,,,reduced virulence,,no,yes,yes,,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35050012,PubMed,10.3390/jof8010072,J Fungi (Basel). 2022 Jan 11;8(1):72,xhliu@zju.edu.cn,"The pathogenicity of conidia in the ΔMoalo1 null mutant was reduced deeply in rice, and defective penetration of appressorium-like structures (ALS) formed by the hyphal tips was also observed in the DMoalo1 null mutant.",M H Wu 2022,2022,1 gene,"Wu-2022-A Putative D-Arabinono-1,4-lactone Oxi",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19467,PHI:11989,UniProt,G5EH52,GenBank,EAQ71017,,,70-15,MoALO1 (MGG_02689),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,"putative D-arabinono-1,4-lactone oxidase",,,,reduced virulence,,no,yes,yes,,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35050012,PubMed,10.3390/jof8010072,J Fungi (Basel). 2022 Jan 11;8(1):72,xhliu@zju.edu.cn,"The pathogenicity of conidia in the ΔMoalo1 null mutant was reduced deeply in rice, and defective penetration of appressorium-like structures (ALS) formed by the hyphal tips was also observed in the DMoalo1 null mutant.",M H Wu 2022,2022,1 gene,"Wu-2022-A Putative D-Arabinono-1,4-lactone Oxi",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19468,PHI:11990,UniProt,no data found,GenBank,,,,,MoBZIP3,,,,,,,318829,Magnaporthe oryzae,1143189,Y34,blast,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,bZip transcription factor,,,,reduced virulence,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35055065,PubMed,10.3390/ijms23020881,Int J Mol Sci. 2022 Jan 14;23(2):881,hanlibo@im.ac.cn,"The bZIP transcription factor MoBZIP3, functions in regulating M. oryzae appressorium turgor formation and infection.",C Liu 2022,2022,1 gene,Liu-2022-Magnaporthe oryzae Transcription Fact,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19469,PHI:11991,,no data found,GenBank,QSI95321,,,IPO2019,dsbA,,,,,,,1089444,Dickeya solani,1225786,IPO 2222,soft rot; blackleg disease,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,periplasmic oxidoreductase,,,,loss of pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35054882,PubMed,10.3390/ijms23020697,Int J Mol Sci. 2022 Jan 9;23(2):697,joanna.skorko-glonek@ug.edu.pl,The mutant bacteria showed lower activities of secreted virulence determinants and were unable to develop disease symptoms in a potato plant.,T Przepiora 2022,2022,1 gene,Przepiora-2022-The Periplasmic Oxidoreductase,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19470,PHI:11991,,no data found,GenBank,QSI95321,,,IPO2019,dsbA,,,,,,,1089444,Dickeya solani,1225786,IPO 2222,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),cv. Vineta; cv. Kondor,,,tuber,periplasmic oxidoreductase,,,,loss of pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35054882,PubMed,10.3390/ijms23020697,Int J Mol Sci. 2022 Jan 9;23(2):697,joanna.skorko-glonek@ug.edu.pl,The mutant bacteria showed lower activities of secreted virulence determinants and were unable to develop disease symptoms in a potato plant.,T Przepiora 2022,2022,1 gene,Przepiora-2022-The Periplasmic Oxidoreductase,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19471,PHI:11992,UniProt,B8NBA7,GenBank,QMW35353,,,NRRL3357,pgi,chromosome 7,,,,,,5059,Aspergillus flavus,,CA14 (Δku70),ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,phosphoglucose isomerase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,calcofluor white; Congo red; sodium dodecyl sulfate; itraconazole; caspofungin; amphotericin B; sorbitol; NaCl; KCl; H2O2,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180; amphotericin B: CHEBI:2682; sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34976860,PubMed,10.3389/fcimb.2021.777266,Front Cell Infect Microbiol. 2021 Dec 15;11:777266,jinc@im.ac.cn,"The Δpgi mutant lost the ability to form sclerotium and displayed hypersusceptibility to osmotic, oxidative, and temperature stresses.",Y Zhou 2021,2021,1 gene,Zhou-2021-Phosphoglucose Isomerase Plays a Key,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19472,PHI:11992,UniProt,B8NBA7,GenBank,QMW35353,,,NRRL3357,pgi,chromosome 7,,,,,,5059,Aspergillus flavus,,CA14 (Δku70),ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,cotyledon,phosphoglucose isomerase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,calcofluor white; Congo red; sodium dodecyl sulfate; itraconazole; caspofungin; amphotericin B; sorbitol; NaCl; KCl; H2O2,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180; amphotericin B: CHEBI:2682; sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34976860,PubMed,10.3389/fcimb.2021.777266,Front Cell Infect Microbiol. 2021 Dec 15;11:777266,jinc@im.ac.cn,"The Δpgi mutant lost the ability to form sclerotium and displayed hypersusceptibility to osmotic, oxidative, and temperature stresses.",Y Zhou 2021,2021,1 gene,Zhou-2021-Phosphoglucose Isomerase Plays a Key,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19473,PHI:11992,UniProt,B8NBA7,GenBank,QMW35353,,,NRRL3357,pgi,chromosome 7,,,,,,5059,Aspergillus flavus,,CA14 (Δku70),ear rot (corn); yellow mold (peanut),nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,phosphoglucose isomerase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,calcofluor white; Congo red; sodium dodecyl sulfate; itraconazole; caspofungin; amphotericin B; sorbitol; NaCl; KCl; H2O2,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180; amphotericin B: CHEBI:2682; sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34976860,PubMed,10.3389/fcimb.2021.777266,Front Cell Infect Microbiol. 2021 Dec 15;11:777266,jinc@im.ac.cn,"The Δpgi mutant lost the ability to form sclerotium and displayed hypersusceptibility to osmotic, oxidative, and temperature stresses.",Y Zhou 2021,2021,1 gene,Zhou-2021-Phosphoglucose Isomerase Plays a Key,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19474,PHI:11992,UniProt,B8NBA7,GenBank,QMW35353,,,NRRL3357,pgi,chromosome 7,,,,,,5059,Aspergillus flavus,,CA14 (Δku70),ear rot (corn); yellow mold (peanut),moths,7137,Galleria mellonella (related: Greater wax moth),,,,,phosphoglucose isomerase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,calcofluor white; Congo red; sodium dodecyl sulfate; itraconazole; caspofungin; amphotericin B; sorbitol; NaCl; KCl; H2O2,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate: CHEBI:8984; itraconazole: CHEBI:6076; caspofungin: CHEBI:474180; amphotericin B: CHEBI:2682; sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34976860,PubMed,10.3389/fcimb.2021.777266,Front Cell Infect Microbiol. 2021 Dec 15;11:777266,jinc@im.ac.cn,"The Δpgi mutant lost the ability to form sclerotium and displayed hypersusceptibility to osmotic, oxidative, and temperature stresses.",Y Zhou 2021,2021,1 gene,Zhou-2021-Phosphoglucose Isomerase Plays a Key,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19475,PHI:11993,UniProt,Q309Y7,GenBank,ABB17358,,,Germ82596,agrA,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,accessory gene regulator protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19476,PHI:11994,UniProt,Q7A1N5,GenBank,BAB94445,,,MW2,sarA,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19477,PHI:11993,UniProt,Q309Y7,GenBank,ABB17358,,,Germ82596,agrA,,,,,,PHI:11994,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,accessory gene regulator protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19478,PHI:11994,UniProt,Q7A1N5,GenBank,BAB94445,,,MW2,sarA,,,,,,PHI:11993,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19479,PHI:11993,UniProt,Q309Y7,GenBank,ABB17358,,,Germ82596,agrA,,,,,,,1280,Staphylococcus aureus,,subsp. aureus strain ATCC 25923,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,accessory gene regulator protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19480,PHI:11994,UniProt,Q7A1N5,GenBank,BAB94445,,,MW2,sarA,,,,,,,1280,Staphylococcus aureus,,subsp. aureus strain ATCC 25923,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19481,PHI:11993,UniProt,Q309Y7,GenBank,ABB17358,,,Germ82596,agrA,,,,,,PHI:11994,1280,Staphylococcus aureus,,subsp. aureus strain ATCC 25923,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,accessory gene regulator protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19482,PHI:11994,UniProt,Q7A1N5,GenBank,BAB94445,,,MW2,sarA,,,,,,PHI:11993,1280,Staphylococcus aureus,,subsp. aureus strain ATCC 25923,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19483,PHI:11993,UniProt,Q309Y7,GenBank,ABB17358,,,Germ82596,agrA,,,,,,,1280,Staphylococcus aureus,,subsp. aureus strain ATCC 1556,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,accessory gene regulator protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19484,PHI:11994,UniProt,Q7A1N5,GenBank,BAB94445,,,MW2,sarA,,,,,,,1280,Staphylococcus aureus,,subsp. aureus strain ATCC 1556,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19485,PHI:11993,UniProt,Q309Y7,GenBank,ABB17358,,,Germ82596,agrA,,,,,,PHI:11994,1280,Staphylococcus aureus,,subsp. aureus strain ATCC 1556,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,accessory gene regulator protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19486,PHI:11994,UniProt,Q7A1N5,GenBank,BAB94445,,,MW2,sarA,,,,,,PHI:11993,1280,Staphylococcus aureus,,subsp. aureus strain ATCC 1556,skin infection; food poisoning; respiratory disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),CF512,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35044945,PubMed,10.3855/jidc.13664,J Infect Dev Ctries. 2021 Dec 31;15(12):1868-1875,paul.brown@uwimona.edu.jm,siRNA targeted to agrA and sarA lowered mRNA transcription and pathogenicity of S. aureus.,T A Thompson 2021,2021,2 genes,Thompson-2021-Small interfering RNAs targeting,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19487,PHI:11995,UniProt,A0A384JHV8,GenBank,ATZ50176,,,B05.10,BcATG6 (BCIN_05g05500),BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,autophagy protein,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34970250,PubMed,10.3389/fmicb.2021.798363,Front Microbiol. 2021 Dec 14;12:798363,renweichaoqw@163.com,"Targeted deletion of the BcATG6 gene showed block of autophagy and several phenotypic defects in aspects of mycelial growth, conidiation, sclerotial formation and virulence.",N Liu 2021,2021,1 gene,Liu-2021-Involvement of the Autophagy Protein,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19488,PHI:11995,UniProt,A0A384JHV8,GenBank,ATZ50176,,,B05.10,BcATG6 (BCIN_05g05500),BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,autophagy protein,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34970250,PubMed,10.3389/fmicb.2021.798363,Front Microbiol. 2021 Dec 14;12:798363,renweichaoqw@163.com,"Targeted deletion of the BcATG6 gene showed block of autophagy and several phenotypic defects in aspects of mycelial growth, conidiation, sclerotial formation and virulence.",N Liu 2021,2021,1 gene,Liu-2021-Involvement of the Autophagy Protein,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19489,PHI:11996,UniProt,A0A3T0ZYX6,GenBank,BBG85471,,,GSH8-2,vasH,,,,,,,644,Aeromonas hydrophila,,GD18,diarrhea; nausea; vomiting,bony fishes,7959,Ctenopharyngodon idella (related: grass carp),,,,spleen; kidney; liver,σ54-transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34966816,PubMed,10.3389/fvets.2021.793458,Front Vet Sci. 2021 Dec 13;8:793458,zhouyang@mail.hzau.edu.cn,"VasH not only contributed to the bacterial cytotoxicity and resistance against host immune cleaning, but also was required for virulence and systemic dissemination of A.hydrophila GD18.",J Li 2021,2021,1 gene,Li-2021-VasH Contributes to Virulence of Aerom,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19490,PHI:11997,UniProt,no data found,GenBank,,,,,lcpB,,,,,,,1280,Staphylococcus aureus,,ST59,skin infection; food poisoning; respiratory disease,even-toed ungulates,9940,Ovis aries (related: sheep),,,,blood,pyrophosphatase,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34975809,PubMed,10.3389/fmicb.2021.788500,Front Microbiol. 2021 Dec 16;12:788500,sunb@ustc.edu.cn,"Knockout of lcpB in the CA-MRSA isolate ST59 resulted in enhanced hemolytic activity, enlarged of abscesses, and increased leukocyte infiltration.",T Pan 2021,2021,1 gene,Pan-2021-LcpB Is a Pyrophosphatase Responsible,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19491,PHI:11997,UniProt,no data found,GenBank,,,,,lcpB,,,,,,,1280,Staphylococcus aureus,,ST59,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,pyrophosphatase,,,,increased virulence (hypervirulence),,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34975809,PubMed,10.3389/fmicb.2021.788500,Front Microbiol. 2021 Dec 16;12:788500,sunb@ustc.edu.cn,"Knockout of lcpB in the CA-MRSA isolate ST59 resulted in enhanced hemolytic activity, enlarged of abscesses, and increased leukocyte infiltration.",T Pan 2021,2021,1 gene,Pan-2021-LcpB Is a Pyrophosphatase Responsible,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19492,PHI:11998,UniProt,G4N6L6,GenBank,EHA50685,,,70-15,Vps13 (MGG_06537),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,vacuolar protein-sorting receptor,,,,reduced virulence,,no,no,,,reduced,,wild type,,no,Congo red; SDS; myriocin; amphotericin B; rapamycin,Congo red: CHEBI:34653; SDS: CHEBI:8984; myriocin: CHEBI:582124; amphotericin B: CHEBI:2682; rapamycin: CHEBI:9168,,,,,gene deletion: full; gene complementation,,,YVS,34947066,PubMed,10.3390/jof7121084,J Fungi (Basel). 2021 Dec 17;7(12):1084,fuchenglin@zju.edu.cn,Deletion mutants of MoVps13 significantly reduced the conidiation and decreased the rate of fungal infection on hosts.,X Zhu 2021,2021,1 gene,Zhu-2021-Vacuolar Protein-Sorting Receptor MoV,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19493,PHI:11998,UniProt,G4N6L6,GenBank,EHA50685,,,70-15,Vps13 (MGG_06537),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4513,Hordeum vulgare (related: barley),,,,leaf,vacuolar protein-sorting receptor,,,,reduced virulence,,no,no,,,reduced,,wild type,,no,Congo red; SDS; myriocin; amphotericin B; rapamycin,Congo red: CHEBI:34653; SDS: CHEBI:8984; myriocin: CHEBI:582124; amphotericin B: CHEBI:2682; rapamycin: CHEBI:9168,,,,,gene deletion: full; gene complementation,,,YVS,34947066,PubMed,10.3390/jof7121084,J Fungi (Basel). 2021 Dec 17;7(12):1084,fuchenglin@zju.edu.cn,Deletion mutants of MoVps13 significantly reduced the conidiation and decreased the rate of fungal infection on hosts.,X Zhu 2021,2021,1 gene,Zhu-2021-Vacuolar Protein-Sorting Receptor MoV,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19494,PHI:11999,UniProt,I1S552,GenBank,ESU06905,,,PH-1,FgPEX22-like (FGSG_11970),chromosome 1,,,FgPEX4,UniProt: I1RRW0; GenBank: CEF85136,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,inflorescence,hypothetical protein,,,,reduced virulence,,,,,,reduced,reduced,wild type,reduced,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34956121,PubMed,10.3389/fmicb.2021.756292,Front Microbiol. 2021 Dec 10;12:756292,jfyu@sdau.edu.cn,"Analysis of the mutant showed that FgPEX22-like was essential for sexual and asexual reproduction, fatty acid utilization, pathogenicity, and production of the mycotoxin deoxynivalenol.",L Zhang 2021,2021,1 gene,Zhang-2021-Peroxin FgPEX22-Like Is Involved in,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19495,PHI:12000,UniProt,A7ELN3,GenBank,EDO03749,,,1980,SS1G_06230 (SsYCP1),,,,,,,5180,Sclerotinia sclerotiorum,,YTK12,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,YML079-like cupin protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,34946121,PubMed,10.3390/microorganisms9122519,Microorganisms. 2021 Dec 6;9(12):2519,wangyp@yzu.edu.cn,Sclerotinia sclerotiorum infection was promoted by SsYCP1 overexpression and inhibited by silencing this gene with synthetic double-stranded RNA.,H Fan 2021,2021,1 gene,Fan-2021-Characterization of a Secretory YML07,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19496,PHI:12000,UniProt,A7ELN3,GenBank,EDO03749,,,1980,SS1G_06230 (SsYCP1),,,,,,,5180,Sclerotinia sclerotiorum,,YTK12,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,YML079-like cupin protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34946121,PubMed,10.3390/microorganisms9122519,Microorganisms. 2021 Dec 6;9(12):2519,wangyp@yzu.edu.cn,Sclerotinia sclerotiorum infection was promoted by SsYCP1 overexpression and inhibited by silencing this gene with synthetic double-stranded RNA.,H Fan 2021,2021,1 gene,Fan-2021-Characterization of a Secretory YML07,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19497,PHI:12001,UniProt,no data found,GenBank,,,,,dkcA,,,,,,,573,Klebsiella pneumoniae,,ST258,pneumonia,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,membrane transporter,,,,reduced virulence,,,,,,,,,,no,colistin,colistin: CHEBI:37943,,,,,gene deletion: full,,,YVS,34934166,PubMed,10.1038/s41598-021-03834-3,Sci Rep. 2021 Dec 21;11(1):24365,wdoerr@lsu.edu,K. pneumoniae ΔdkcA displays reduced virulence in Galleria mellonella suggesting colistin sensitivity can cause loss of virulence.,V Tiwari 2021,2021,1 gene,Tiwari-2021-A Klebsiella pneumoniae DedA famil,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19498,PHI:12002,UniProt,P9WJA5,GenBank,CCP44723,,,H37Rv,Rv1955 (HigB1),,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10141,Cavia porcellus (related: Domestic Guinea pig),,,,lung; spleen,toxin,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; NaNO2; SDS; isoniazid; rifampicin; levofloxacin,H2O2: CHEBI:16240; NaNO2: CHEBI:78870; SDS: CHEBI:8984; isoniazid: CHEBI:6030; rifampicin: CHEBI:28077; levofloxacin: CHEBI:63598,,,,,gene deletion: full; gene complementation,,,YVS,34917044,PubMed,10.3389/fmicb.2021.748890,Front Microbiol. 2021 Nov 30;12:748890,amitagupta@south.du.ac.in,Guinea pigs infected with higB1 deletion strain exhibited significantly reduced bacterial loads and pathological damage in comparison to the animals infected with the parental strain.,A Sharma 2021,2021,1 gene,Sharma-2021-HigB1 Toxin in Mycobacterium tuber,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19499,PHI:12003,UniProt,A0A063C6W8,,,,,,Kmt6 (KDB18066),,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,putative PRC2 catalytic subunit,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl; sorbitol; calcofluor white; Congo red; SDS; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34895056,PubMed,10.1080/21505594.2021.2008150,Virulence. 2021 Dec;12(1):2972-2988,kouyanjun@caas.cn,"Disruption of UvKMT6 resulted in reduced growth, conidiation and pathogenicity in U. virens.",S Meng 2021,2021,1 gene,Meng-2021-UvKmt6-mediated H3K27 trimethylation,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19500,PHI:12004,UniProt,no data found,GenBank,,,,,sRNA23,,,,,,,1307,Streptococcus suis,391295,05ZYH33,meningitis; septicemia; arthritis; pneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),,,,blood,small non-coding RNA,,,,reduced virulence,,,,,,,,,,no,"2,2'-bipyridine; NaCl; paraquat","2,2'-bipyridine,  NaCl: CHEBI:26710; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,34882070,PubMed,10.1080/21505594.2021.2008177,Virulence. 2021 Dec;12(1):3045-3061,fafuchenye@163.com,sRNA23 deletion impaired adhesion and hemolytic activity and enhances susceptibility toward phagocytosis.,Q Xu 2021,2021,1 gene,"Xu-2021-sRNA23, a novel small RNA, regulates t",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19501,PHI:12004,UniProt,no data found,GenBank,,,,,sRNA23,,,,,,,1307,Streptococcus suis,391295,05ZYH33,meningitis; septicemia; arthritis; pneumonia (pig),primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,small non-coding RNA,,,,reduced virulence,,,,,,,,,,no,"2,2'-bipyridine; NaCl; paraquat","2,2'-bipyridine,  NaCl: CHEBI:26710; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,34882070,PubMed,10.1080/21505594.2021.2008177,Virulence. 2021 Dec;12(1):3045-3061,fafuchenye@163.com,sRNA23 deletion impaired adhesion and hemolytic activity and enhances susceptibility toward phagocytosis.,Q Xu 2021,2021,1 gene,"Xu-2021-sRNA23, a novel small RNA, regulates t",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19502,PHI:12004,UniProt,no data found,GenBank,,,,,sRNA23,,,,,,,1307,Streptococcus suis,391295,05ZYH33,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,small non-coding RNA,,,,reduced virulence,,,,,,,,,,no,"2,2'-bipyridine; NaCl; paraquat","2,2'-bipyridine,  NaCl: CHEBI:26710; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,34882070,PubMed,10.1080/21505594.2021.2008177,Virulence. 2021 Dec;12(1):3045-3061,fafuchenye@163.com,sRNA23 deletion impaired adhesion and hemolytic activity and enhances susceptibility toward phagocytosis.,Q Xu 2021,2021,1 gene,"Xu-2021-sRNA23, a novel small RNA, regulates t",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19503,PHI:12004,UniProt,no data found,GenBank,,,,,sRNA23,,,,,,,1307,Streptococcus suis,391295,05ZYH33,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,alveolar wall,small non-coding RNA,,,,reduced virulence,,,,,,,,,,no,"2,2'-bipyridine; NaCl; paraquat","2,2'-bipyridine,  NaCl: CHEBI:26710; paraquat: CHEBI:34905",,,,,gene deletion: full; gene complementation,,,YVS,34882070,PubMed,10.1080/21505594.2021.2008177,Virulence. 2021 Dec;12(1):3045-3061,fafuchenye@163.com,sRNA23 deletion impaired the pathogenicity of 05ZYH33 in mice.,Q Xu 2021,2021,1 gene,"Xu-2021-sRNA23, a novel small RNA, regulates t",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19504,PHI:12006,UniProt,Q9I5E0,GenBank,AE004515_3,,,PAO1,pmtA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,phospholipid methyltransferase,,,,reduced virulence,,,,,,,,,,no,cefepime; ciprofloxacin; H2O2,cefepime: CHEBI:478164; ciprofloxacin: CHEBI:100241; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34867928,PubMed,10.3389/fmicb.2021.789765,Front Microbiol. 2021 Nov 15;12:789765,Michael.lynes@uconn.edu,The ΔpmtA mutant was disrupted for biofilm formation.,A V Thees 2021,2021,1 gene,Thees-2021-PmtA Regulates Pyocyanin Expression,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19505,PHI:12007,UniProt,I1RPD6,GenBank,CEF88547,,,PH-1,Fgspe1 (FGSG_05903),chromosome 3,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile; leaf,uncharacterized protein,,,spermidine biosynthesis,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34867896,PubMed,10.3389/fmicb.2021.765398,Front Microbiol. 2021 Nov 19;12:765398,liuwende@caas.cn,"The ΔFgspe2 and ΔFgspe3 demonstrated attenuated virulence on seedling leaves, corn silk, and wheat coleoptiles.",G Tang 2021,2021,4 genes,"Tang-2021-Spermidine Is Critical for Growth, D",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19506,PHI:12008,UniProt,I1RYR7,GenBank,CEF84603,,,PH-1,Fgspe4 (FGSG_09525),chromosome 4,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile; leaf,uncharacterized protein,,,spermidine biosynthesis,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34867896,PubMed,10.3389/fmicb.2021.765398,Front Microbiol. 2021 Nov 19;12:765398,liuwende@caas.cn,"The ΔFgspe2 and ΔFgspe3 demonstrated attenuated virulence on seedling leaves, corn silk, and wheat coleoptiles.",G Tang 2021,2021,4 genes,"Tang-2021-Spermidine Is Critical for Growth, D",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19507,PHI:12009,UniProt,I1RXG6,GenBank,CEF85480,,,PH-1,Fgspe2 (FGSG_09035),chromosome 4,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile; leaf,adenosylmethionine decarboxylase,,,spermidine biosynthesis,reduced virulence,,,yes,,,reduced,reduced,reduced,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34867896,PubMed,10.3389/fmicb.2021.765398,Front Microbiol. 2021 Nov 19;12:765398,liuwende@caas.cn,"The ΔFgspe2 and ΔFgspe3 demonstrated attenuated virulence on seedling leaves, corn silk, and wheat coleoptiles.",G Tang 2021,2021,4 genes,"Tang-2021-Spermidine Is Critical for Growth, D",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19508,PHI:12010,UniProt,A0A1C3YJ36,GenBank,SCB64583,,,PH-1,Fgspe3 (FGSG_11970),chromosome 1,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile; leaf,PABS domain-containing protein,,,spermidine biosynthesis,reduced virulence,,,yes,,,reduced,reduced,reduced,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34867896,PubMed,10.3389/fmicb.2021.765398,Front Microbiol. 2021 Nov 19;12:765398,liuwende@caas.cn,"The ΔFgspe2 and ΔFgspe3 demonstrated attenuated virulence on seedling leaves, corn silk, and wheat coleoptiles.",G Tang 2021,2021,4 genes,"Tang-2021-Spermidine Is Critical for Growth, D",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19509,PHI:12007,UniProt,I1RPD6,GenBank,CEF88547,,,PH-1,Fgspe1 (FGSG_05903),chromosome 3,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,uncharacterized protein,,,spermidine biosynthesis,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34867896,PubMed,10.3389/fmicb.2021.765398,Front Microbiol. 2021 Nov 19;12:765398,liuwende@caas.cn,"The ΔFgspe2 and ΔFgspe3 demonstrated attenuated virulence on seedling leaves, corn silk, and wheat coleoptiles.",G Tang 2021,2021,4 genes,"Tang-2021-Spermidine Is Critical for Growth, D",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19510,PHI:12008,UniProt,I1RYR7,GenBank,CEF84603,,,PH-1,Fgspe4 (FGSG_09525),chromosome 4,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,uncharacterized protein,,,spermidine biosynthesis,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34867896,PubMed,10.3389/fmicb.2021.765398,Front Microbiol. 2021 Nov 19;12:765398,liuwende@caas.cn,"The ΔFgspe2 and ΔFgspe3 demonstrated attenuated virulence on seedling leaves, corn silk, and wheat coleoptiles.",G Tang 2021,2021,4 genes,"Tang-2021-Spermidine Is Critical for Growth, D",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19511,PHI:12009,UniProt,I1RXG6,GenBank,CEF85480,,,PH-1,Fgspe2 (FGSG_09035),chromosome 4,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,adenosylmethionine decarboxylase,,,spermidine biosynthesis,reduced virulence,,,yes,,,reduced,reduced,reduced,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34867896,PubMed,10.3389/fmicb.2021.765398,Front Microbiol. 2021 Nov 19;12:765398,liuwende@caas.cn,"The ΔFgspe2 and ΔFgspe3 demonstrated attenuated virulence on seedling leaves, corn silk, and wheat coleoptiles.",G Tang 2021,2021,4 genes,"Tang-2021-Spermidine Is Critical for Growth, D",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19512,PHI:12010,UniProt,A0A1C3YJ36,GenBank,SCB64583,,,PH-1,Fgspe3 (FGSG_11970),chromosome 1,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,PABS domain-containing protein,,,spermidine biosynthesis,reduced virulence,,,yes,,,reduced,reduced,reduced,,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34867896,PubMed,10.3389/fmicb.2021.765398,Front Microbiol. 2021 Nov 19;12:765398,liuwende@caas.cn,"The ΔFgspe2 and ΔFgspe3 demonstrated attenuated virulence on seedling leaves, corn silk, and wheat coleoptiles.",G Tang 2021,2021,4 genes,"Tang-2021-Spermidine Is Critical for Growth, D",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19513,PHI:12011,UniProt,no data found,GenBank,,,,,ern0160,,,,,,,1352,Enterococcus faecium,,Aus0004,nosocomial bacteremia,rodents,10090,Mus musculus (related: house mouse),SWR,,,gastrointestinal tract,regulatory RNA,,,,reduced virulence,,,,,,,,wild type,,no,ceftriaxone; cefoxitin; amoxicillin,ceftriaxone: CHEBI:29007; cefoxitin: CHEBI:209807; amoxicillin: CHEBI:2676,,,,,gene deletion: full; gene complementation,,,YVS,34858368,PubMed,10.3389/fmicb.2021.757227,Front Microbiol. 2021 Nov 10;12:757227,matthieu.revest@chu-rennes.fr,An overexpression of ern0160 was found to be deleterious to the strain in GIT colonization.,S Reissier 2021,2021,1 gene,Reissier-2021-The Regulatory RNA ern0160 Confe,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19514,PHI:12011,UniProt,no data found,GenBank,,,,,ern0160,,,,,,,1352,Enterococcus faecium,,Aus0004,nosocomial bacteremia,rodents,10090,Mus musculus (related: house mouse),SWR,,,gastrointestinal tract,regulatory RNA,,,,reduced virulence,,,,,,,,reduced,,no,ceftriaxone; cefoxitin; amoxicillin,ceftriaxone: CHEBI:29007; cefoxitin: CHEBI:209807; amoxicillin: CHEBI:2676,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34858368,PubMed,10.3389/fmicb.2021.757227,Front Microbiol. 2021 Nov 10;12:757227,matthieu.revest@chu-rennes.fr,An overexpression of ern0160 was found to be deleterious to the strain in GIT colonization.,S Reissier 2021,2021,1 gene,Reissier-2021-The Regulatory RNA ern0160 Confe,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19515,PHI:12012,UniProt,no data found,GenBank,,,,,lncRsp1,,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhengmai 9023,,,inflorescence; coleoptile,long noncoding RNA,,,,reduced virulence,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34841640,PubMed,10.1111/mpp.13160,Mol Plant Pathol. 2022 Feb;23(2):265-277,yanglin@mail.hzau.edu.cn,"The overexpression of lncRsp1 enhanced the ability of ascospore release and increased the mRNA expression level of the Fgsp1 gene, while lncRsp1- silenced strains reduced ascospore discharge and inhibited Fgsp1 expression during the sexual reproduction stage.",J Wang 2022,2022,2 genes,"Wang-2022-lncRsp1, a long noncoding RNA, influ",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19516,PHI:12013,UniProt,V6R9L0,GenBank,CEF87204,,,PH-1,Fgsp1 (FGSG_05042),chromosome 3,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhengmai 9023,,,inflorescence; coleoptile,major facilitator superfamily (MFS) transport protein,,,,reduced virulence,,,,,,wild type,reduced,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34841640,PubMed,10.1111/mpp.13160,Mol Plant Pathol. 2022 Feb;23(2):265-277,yanglin@mail.hzau.edu.cn,"The overexpression of lncRsp1 enhanced the ability of ascospore release and increased the mRNA expression level of the Fgsp1 gene, while lncRsp1- silenced strains reduced ascospore discharge and inhibited Fgsp1 expression during the sexual reproduction stage.",J Wang 2022,2022,2 genes,"Wang-2022-lncRsp1, a long noncoding RNA, influ",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19517,PHI:12014,UniProt,P0A910,GenBank,AAC74043,,,K-12,ompA,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,intestine,outer membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34832651,PubMed,10.3390/pathogens10111496,Pathogens. 2021 Nov 17;10(11):1496,hirakawa@gunma-u.ac.jp,Mice infected with ompA mutant developed symptoms of diarrhea more slowly than mice infected with the parent strain.,H Hirakawa 2021,2021,1 gene,Hirakawa-2021-Roles of OmpA in Type III Secret,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19518,PHI:12014,UniProt,P0A910,GenBank,AAC74043,,,K-12,ompA,,,,,,,562,Escherichia coli,,serotype O157,diarrhea; hemorrhagic colitis; hemolytic uremic syndrome,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,intestine,outer membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34832651,PubMed,10.3390/pathogens10111496,Pathogens. 2021 Nov 17;10(11):1496,hirakawa@gunma-u.ac.jp,Mice infected with ompA mutant developed symptoms of diarrhea more slowly than mice infected with the parent strain.,H Hirakawa 2021,2021,1 gene,Hirakawa-2021-Roles of OmpA in Type III Secret,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19519,PHI:12014,UniProt,P0A910,GenBank,AAC74043,,,K-12,ompA,,,,,,,562,Escherichia coli,,serotype O157,diarrhea; hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,outer membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34832651,PubMed,10.3390/pathogens10111496,Pathogens. 2021 Nov 17;10(11):1496,hirakawa@gunma-u.ac.jp,The ompA mutant had less abilities to form A/E lesions in host epithelial cells and lyse human red blood cells than the parent strain.,H Hirakawa 2021,2021,1 gene,Hirakawa-2021-Roles of OmpA in Type III Secret,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19520,PHI:12014,UniProt,P0A910,GenBank,AAC74043,,,K-12,ompA,,,,,,,562,Escherichia coli,,serotype O157,diarrhea; hemorrhagic colitis; hemolytic uremic syndrome,primates,9606,Homo sapiens (related: human),,,,erythrocyte,outer membrane protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34832651,PubMed,10.3390/pathogens10111496,Pathogens. 2021 Nov 17;10(11):1496,hirakawa@gunma-u.ac.jp,The ompA mutant had less abilities to form A/E lesions in host epithelial cells and lyse human red blood cells than the parent strain.,H Hirakawa 2021,2021,1 gene,Hirakawa-2021-Roles of OmpA in Type III Secret,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19521,PHI:12015,UniProt,G4N0T8,GenBank,EHA51521,,,70-15,MoAE4 (MGG_15203),chromosome 3,,,,,,318829,Magnaporthe oryzae,,JJ88,blast,monocots,4530,Oryza sativa (related: rice),cv. Jijing 88,,,leaf,anion exchange protein 4,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,wild type,no,H2O2; NaHCO3,H2O2: CHEBI:16240; NaHCO3: CHEBI:32139,,,,,gene deletion: full; gene complementation,,,YVS,34829242,PubMed,10.3390/jof7110955,J Fungi (Basel). 2021 Nov 11;7(11):955,zhangsh89@syau.edu.cn,"ΔMoAE4 was defective in conidiation, appressorium formation, and pathogenicity.",Y Dang 2021,2021,1 gene,Dang-2021-The Bicarbonate Transporter (MoAE4),BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19522,PHI:12016,UniProt,E9DTB1,GenBank,EFY92966,,,CQMa 102,MaNmrA (MAC_00749),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,hemolymph,negative regulatory protein,,,,reduced virulence,,yes,yes,yes,,reduced,,increased; aberrant,reduced,no,NaCl; sorbitol; calcofluor white; Congo red; SDS; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,34827160,PubMed,10.3390/biology10111167,Biology (Basel). 2021 Nov 12;10(11):1167,yuxianxia@cqu.edu.cn,The pathogenic ability of M. acridum was decreased in the absence of MaNmrA.,C Li 2021,2021,1 gene,"Li-2021-MaNmrA, a Negative Transcription Regul",BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19523,PHI:12017,UniProt,G2WTP4,GenBank,EGY17485,,,VdLs.17,VDAG_01167,chromosome 1,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,shoot,pleotropic drug transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34825755,PubMed,10.1111/mpp.13162,Mol Plant Pathol. 2022 Feb;23(2):291-303,Georgios.tzelepis@slu.se,No significant differences in shoot length were recorded between plants infected with the WT and the VDAG_01167 deletion strain.,V Rafiei 2022,2022,2 genes,Rafiei-2022-A Verticillium longisporum pleiotr,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19524,PHI:12018,UniProt,A0A0G4LQQ7,GenBank,CRK24376,,,VL1,VlAbcG1a (BN1708_013935),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,shoot,pleotropic drug transporter,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,heterologous expression; altered gene expression/ gene regulation: overexpression,,,YVS,34825755,PubMed,10.1111/mpp.13162,Mol Plant Pathol. 2022 Feb;23(2):291-303,Georgios.tzelepis@slu.se,The VlAbcG1a overexpression strain displayed an increased tolerance to β- pinene and increased virulence in tomato plants.,V Rafiei 2022,2022,2 genes,Rafiei-2022-A Verticillium longisporum pleiotr,BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19525,PHI:12019,UniProt,Q9A1R6,GenBank,AAK33244,,,SF370,cef (Spy0136),,,,,,,1314,Streptococcus pyogenes,,SF370,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,complement evasion factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35094646,PubMed,10.1080/21505594.2022.2027629,Virulence. 2022 Dec;13(1):225-240,t.proft@auckland.ac.nz,An S. pyogenes Δspy0136/cef deletion mutant showed decreased virulence in an in-vitro whole blood killing assay and a Galleria mellonella (wax moth) infection model.,H Aghababa 2022,2022,1 gene,Aghababa-2022-Complement evasion factor (CEF),BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19526,PHI:12019,UniProt,Q9A1R6,GenBank,AAK33244,,,SF370,cef (Spy0136),,,,,,,1314,Streptococcus pyogenes,,SF370,infection,primates,9606,Homo sapiens (related: human),,,,blood,complement evasion factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35094646,PubMed,10.1080/21505594.2022.2027629,Virulence. 2022 Dec;13(1):225-240,t.proft@auckland.ac.nz,An S. pyogenes Δspy0136/cef deletion mutant showed decreased virulence in an in-vitro whole blood killing assay and a Galleria mellonella (wax moth) infection model.,H Aghababa 2022,2022,1 gene,Aghababa-2022-Complement evasion factor (CEF),BATCH_110A,2022-02-01,MC,,,,,,,,,,,,,
,,Record 19527,PHI:12020,UniProt,Q72SM7,GenBank,AAS69953,,,Fiocruz L1-130,lipL32,chromosome I,,,,,,173,Leptospira interrogans,,serovar Copenhageni strain Fiocruz L1-130,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,liver; kidney,outer membrane lipoprotein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35185824,PubMed,10.3389/fmicb.2021.799012,Front Microbiol. 2022 Feb 2;12:799012,luis.fernandes@esib.butantan.gov.br,The LipL32 mutant displayed augmented virulence as evidenced by early onset of clinical symptoms and increased numbers of circulating foamy macrophages.,L G V Fernandes 2021,2021,3 genes,Fernandes-2021-Evaluation of LipL32 and LigA_L,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19528,PHI:12021,UniProt,G1UB65,GenBank,AAS69086,,,Fiocruz L1-130,ligA,chromosome I,,,,,PHI:12022,173,Leptospira interrogans,,serovar Copenhageni strain Fiocruz L1-130,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,liver; kidney,leptospiral immunoglobulin like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35185824,PubMed,10.3389/fmicb.2021.799012,Front Microbiol. 2022 Feb 2;12:799012,luis.fernandes@esib.butantan.gov.br,"The LigAB mutant was unable to cause acute disease although mutant leptospires could still be recovered from target organs, albeit at a significantly lower bacterial burden.",L G V Fernandes 2021,2021,3 genes,Fernandes-2021-Evaluation of LipL32 and LigA_L,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19529,PHI:12022,UniProt,Q72V39,GenBank,AAS69085,,,Fiocruz L1-130,ligB,chromosome I,,,,,PHI:12021,173,Leptospira interrogans,,serovar Copenhageni strain Fiocruz L1-130,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,liver; kidney,leptospiral immunoglobulin like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,YVS,35185824,PubMed,10.3389/fmicb.2021.799012,Front Microbiol. 2022 Feb 2;12:799012,luis.fernandes@esib.butantan.gov.br,"The LigAB mutant was unable to cause acute disease although mutant leptospires could still be recovered from target organs, albeit at a significantly lower bacterial burden.",L G V Fernandes 2021,2021,3 genes,Fernandes-2021-Evaluation of LipL32 and LigA_L,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19530,PHI:12023,UniProt,Q4WDM5,GenBank,EAL85513,,,Af293,gpi7,chromosome 6,,,,,,746128,Aspergillus fumigatus,,,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,phosphoethanolamine transferase,,,,increased virulence (hypervirulence),,,,,,,,,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34956933,PubMed,10.3389/fcimb.2021.780959,Front Cell Infect Microbiol. 2021 Dec 9;11:780959,ouyanghm@im.ac.cn,"The lack of Gpi7 led to fast germination, stronger immune response, and resistance to macrophage killing.",H Ouyang 2021,2021,1 gene,Ouyang-2021-Deficiency of GPI Glycan Modificat,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19531,PHI:12023,UniProt,Q4WDM5,GenBank,EAL85513,,,Af293,gpi7,chromosome 6,,,,,,746128,Aspergillus fumigatus,,,invasive pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,phosphoethanolamine transferase,,,,increased virulence (hypervirulence),,,,,,,,,aberrant,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34956933,PubMed,10.3389/fcimb.2021.780959,Front Cell Infect Microbiol. 2021 Dec 9;11:780959,ouyanghm@im.ac.cn,"The lack of Gpi7 led to fast germination, stronger immune response, and resistance to macrophage killing.",H Ouyang 2021,2021,1 gene,Ouyang-2021-Deficiency of GPI Glycan Modificat,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19532,PHI:12024,UniProt,Q84GR3,GenBank,CFQ21216,,,SZ375/04,yopP,,,,,,,630,Yersinia enterocolitica,1194086,WA-314,yersiniosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6 (Lgals1<-/->),,,peritoneal macrophage,Yersinia outer protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34827634,PubMed,10.3390/biom11111636,Biomolecules. 2021 Nov 4;11(11):1636,rcdavici@unsl.edu.ar,Lack of Gal1 and YopP induces NO production and confers protection against Ye. Host gene alteration data available for Galectin-1 (Gal1).,B L Jofre 2021,2021,1 gene,Jofre-2021-Galectin-1 Cooperates with Yersinia,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19533,PHI:12025,UniProt,J5JDJ5,GenBank,EJP64008,,,ARSEF 2860,set2,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"histone-lysine N-methyltransferase, H3 lysine-36 specific",,,,reduced virulence,,,,,,,,reduced,,no,"NaCl; menadione; H2O2, Congo red; calcofluor white; sorbitol",NaCl: CHEBI:26710; menadione: CHEBI:28869; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34829243,PubMed,10.3390/jof7110956,J Fungi (Basel). 2021 Nov 11;7(11):956,mgfeng@zju.edu.cn,The Δset2 mutant was more compromised in conidial adherence to insect cuticle and proliferation in vivo than the Δash1 mutant.,K Ren 2021,2021,2 genes,Ren-2021-Conserved and Noncanonical Activities,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19534,PHI:12026,UniProt,J4UIG7,GenBank,EJP63307,,,ARSEF 2860,ash1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,SET domain-containing protein,,,,reduced virulence,,,,,,,,wild type,,no,"NaCl; menadione; H2O2, Congo red; calcofluor white; sorbitol",NaCl: CHEBI:26710; menadione: CHEBI:28869; H2O2: CHEBI:16240; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34829243,PubMed,10.3390/jof7110956,J Fungi (Basel). 2021 Nov 11;7(11):956,mgfeng@zju.edu.cn,The Δset2 mutant was more compromised in conidial adherence to insect cuticle and proliferation in vivo than the Δash1 mutant.,K Ren 2021,2021,2 genes,Ren-2021-Conserved and Noncanonical Activities,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19535,PHI:12027,UniProt,A0A0P0AID0,GenBank,ALI59182,,,CCBH4851,rtcB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,putative RNA ligase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34830443,PubMed,10.3390/ijms222212561,Int J Mol Sci. 2021 Nov 22;22(22):12561,Kangmin.Duan@umanitoba.ca,The three T6SSs were activated upon deletion of rtcB and promoted the pathogenicity of P. aeruginosa.,M Dadashi 2021,2021,2 genes,Dadashi-2021-Putative RNA Ligase RtcB Affects,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19536,PHI:12028,UniProt,Q9HUV7,GenBank,AE004899_2,,,PAO1,retS,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,sensor kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34830443,PubMed,10.3390/ijms222212561,Int J Mol Sci. 2021 Nov 22;22(22):12561,Kangmin.Duan@umanitoba.ca,The three T6SSs were activated upon deletion of rtcB and promoted the pathogenicity of P. aeruginosa.,M Dadashi 2021,2021,2 genes,Dadashi-2021-Putative RNA Ligase RtcB Affects,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19537,PHI:12027,UniProt,A0A0P0AID0,GenBank,ALI59182,,,CCBH4851,rtcB,,,,,,PHI:12028,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,putative RNA ligase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34830443,PubMed,10.3390/ijms222212561,Int J Mol Sci. 2021 Nov 22;22(22):12561,Kangmin.Duan@umanitoba.ca,The three T6SSs were activated upon deletion of rtcB and promoted the pathogenicity of P. aeruginosa.,M Dadashi 2021,2021,2 genes,Dadashi-2021-Putative RNA Ligase RtcB Affects,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19538,PHI:12028,UniProt,Q9HUV7,GenBank,AE004899_2,,,PAO1,retS,,,,,,PHI:12027,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,sensor kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34830443,PubMed,10.3390/ijms222212561,Int J Mol Sci. 2021 Nov 22;22(22):12561,Kangmin.Duan@umanitoba.ca,The three T6SSs were activated upon deletion of rtcB and promoted the pathogenicity of P. aeruginosa.,M Dadashi 2021,2021,2 genes,Dadashi-2021-Putative RNA Ligase RtcB Affects,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19539,PHI:12029,UniProt,A0A806GD53,GenBank,AEX67621,,,C7 (beta),oxyR,,,,,,,1717,Corynebacterium diphtheriae,698965,CDC-E8392,diphtheria,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,LysR-family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene disruption,,,YVS,35169995,PubMed,10.1007/s42770-022-00710-8,Braz J Microbiol. 2022 Feb 16,louisysanchesuerj@gmail.com,OxyR attenuated the arthritogenic potential of C. diphtheriae CDC-E8392 strain.,Cappelli 2022,2022,1 gene,Cappelli-2022-Insights of OxyR role in mechani,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19540,PHI:12029,UniProt,A0A806GD53,GenBank,AEX67621,,,C7 (beta),oxyR,,,,,,,1717,Corynebacterium diphtheriae,698965,CDC-E8392,diphtheria,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,HEp-2 cell,LysR-family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene disruption,,,YVS,35169995,PubMed,10.1007/s42770-022-00710-8,Braz J Microbiol. 2022 Feb 16,louisysanchesuerj@gmail.com,OxyR attenuated the arthritogenic potential of C. diphtheriae CDC-E8392 strain.,Cappelli 2022,2022,1 gene,Cappelli-2022-Insights of OxyR role in mechani,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19541,PHI:12029,UniProt,A0A806GD53,GenBank,AEX67621,,,C7 (beta),oxyR,,,,,,,1717,Corynebacterium diphtheriae,698965,CDC-E8392,diphtheria,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,LysR-family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene disruption,,,YVS,35169995,PubMed,10.1007/s42770-022-00710-8,Braz J Microbiol. 2022 Feb 16,louisysanchesuerj@gmail.com,OxyR attenuated the arthritogenic potential of C. diphtheriae CDC-E8392 strain.,Cappelli 2022,2022,1 gene,Cappelli-2022-Insights of OxyR role in mechani,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19542,PHI:12029,UniProt,A0A806GD53,GenBank,AEX67621,,,C7 (beta),oxyR,,,,,,,1717,Corynebacterium diphtheriae,698965,CDC-E8392,diphtheria,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,LysR-family transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene disruption,,,YVS,35169995,PubMed,10.1007/s42770-022-00710-8,Braz J Microbiol. 2022 Feb 16,louisysanchesuerj@gmail.com,OxyR attenuated the arthritogenic potential of C. diphtheriae CDC-E8392 strain.,Cappelli 2022,2022,1 gene,Cappelli-2022-Insights of OxyR role in mechani,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19543,PHI:12030,UniProt,no data found,GenBank,,,,,Vvde1 (VVMO6_3032),,,,,,,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,glycogen debranching enzyme,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35157220,PubMed,10.1007/s12275-022-1507-3,J Microbiol. 2022 Feb 14,kjw5864@inu.ac.kr,Virulence of the pathogen against Caenorhabditis elegans was attenuated significantly by the vvde1 mutation.,A R Han 2022,2022,1 gene,Han-2022-Characterization of a cold-adapted de,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19544,PHI:12031,UniProt,I1RJR2,GenBank,CEF79036,,,PH-1,FgCYP51A,chromosome 2,G443S substitution mutant,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,sterol 14-alpha demethylase,,,,reduced virulence,,,,,,increased,aberrant,wild type,,no,tebuconazole; metconazole; ipconazole; triticonazole; difenoconazole; epoxiconazole; prothioconazole; prochloraz,tebuconazole: CHEBI:81781; metconazole: CHEBI:81773; ipconazole: CHEBI:81770; triticonazole: CHEBI:81980; difenoconazole: CHEBI:81760; epoxiconazole: CHEBI:4811; prothioconazole: CHEBI:82036; prochloraz: CHEBI:8434,,,,,gene mutation; gene complementation,,,YVS,35129347,PubMed,10.1021/acs.jafc.1c07543,J Agric Food Chem. 2022 Feb 16;70(6):1788-1798,dyb@njau.edu.cn,The FgCYP51A-G443S substitution decreased sexual reproduction and virulence.,H Zhao 2022,2022,1 gene,Zhao-2022-Mechanism of Fusarium graminearum Re,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19545,PHI:12031,UniProt,I1RJR2,GenBank,CEF79036,,,PH-1,FgCYP51A,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence,sterol 14-alpha demethylase,,,,reduced virulence,,,,,,reduced,aberrant,reduced,,no,tebuconazole; metconazole; ipconazole; triticonazole; difenoconazole; epoxiconazole; prothioconazole; prochloraz,tebuconazole: CHEBI:81781; metconazole: CHEBI:81773; ipconazole: CHEBI:81770; triticonazole: CHEBI:81980; difenoconazole: CHEBI:81760; epoxiconazole: CHEBI:4811; prothioconazole: CHEBI:82036; prochloraz: CHEBI:8434,,,,,gene deletion: full; gene complementation,,,YVS,35129347,PubMed,10.1021/acs.jafc.1c07543,J Agric Food Chem. 2022 Feb 16;70(6):1788-1798,dyb@njau.edu.cn,The FgCYP51A-G443S substitution decreased sexual reproduction and virulence.,H Zhao 2022,2022,1 gene,Zhao-2022-Mechanism of Fusarium graminearum Re,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19546,PHI:12032,UniProt,Q6FTD2,GenBank,CAG59439,,,CBS 138,flo8,chromosome G,,,,,,5478,Candida glabrata,,ATCC 2001,disseminated candidiasis,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,transcription factor,,,,reduced virulence,,,,,,,,,,no,fluconazole; voriconazole; itraconazole,fluconazole: CHEBI:46081; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076,,,,,gene deletion: full; gene complementation,,,YVS,35122657,PubMed,10.1007/s42770-022-00703-7,Braz J Microbiol. 2022 Feb 5,mjxiang123456@126.com,Deletion FLO8 led to reduced adhesion of C. glabrata to epithelial cells.,J T Zhao 2022,2022,1 gene,Zhao-2022-FLO8 deletion leads to decreased adh,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19547,PHI:12032,UniProt,Q6FTD2,GenBank,CAG59439,,,CBS 138,flo8,chromosome G,,,,,,5478,Candida glabrata,,ATCC 2001,disseminated candidiasis,primates,9606,Homo sapiens (related: human),VK2/E6E7 cell line,,,epithelial cell,transcription factor,,,,reduced virulence,,,,,,,,,,no,fluconazole; voriconazole; itraconazole,fluconazole: CHEBI:46081; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076,,,,,gene deletion: full; gene complementation,,,YVS,35122657,PubMed,10.1007/s42770-022-00703-7,Braz J Microbiol. 2022 Feb 5,mjxiang123456@126.com,Deletion FLO8 led to reduced adhesion of C. glabrata to epithelial cells.,J T Zhao 2022,2022,1 gene,Zhao-2022-FLO8 deletion leads to decreased adh,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19548,PHI:12033,UniProt,Q0PAM5,GenBank,CAL34788,,,NCTC 11168,cbrR,,,,,,,197,Campylobacter jejuni,,DRH212,gastroenteritis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,Intestine-407 cell,cyclic-di-GMP regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35056537,PubMed,10.3390/microorganisms10010086,Microorganisms. 2021 Dec 31;10(1):86,stthomps@augusta.edu,"WT and cbrR- cells both attached and invaded cells at a similar magnitude; however, cbrR+ cells were deficient in adherence and unable to invade human INT407 cells efficiently.",C A Cox 2021,2021,1 gene,Cox-2021-The Campylobacter jejuni Response Reg,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19549,PHI:12033,UniProt,Q0PAM5,GenBank,CAL34788,,,NCTC 11168,cbrR,,,,,,,197,Campylobacter jejuni,,DRH212,gastroenteritis,primates,9606,Homo sapiens (related: human),Intestine 407 cell line,,,Intestine-407 cell,cyclic-di-GMP regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,35056537,PubMed,10.3390/microorganisms10010086,Microorganisms. 2021 Dec 31;10(1):86,stthomps@augusta.edu,"WT and cbrR- cells both attached and invaded cells at a similar magnitude; however, cbrR+ cells were deficient in adherence and unable to invade human INT407 cells efficiently.",C A Cox 2021,2021,1 gene,Cox-2021-The Campylobacter jejuni Response Reg,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19550,PHI:12034,UniProt,C3VHN8,GenBank,ACP30470,,,CKUH,vvpE,,,,,,PHI:12035,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),3T3-L1,,,3T3-L1 cell,neutral metalloproteinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35102528,PubMed,10.1007/s12275-022-1448-x,J Microbiol. 2022 Feb;60(2):224-233,b.kim@ewha.ac.kr,PlpA-defective V. vulnificus significantly augmented host cell blebbing.,C Cho 2022,2022,3 genes,Cho-2022-Vibrio vulnificus PlpA facilitates ne,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19551,PHI:12035,UniProt,P19247,GenBank,AAO07360,,,CMCP6,vvhA,chromosome II,,,,,PHI:12034,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),3T3-L1,,,3T3-L1 cell,cytolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35102528,PubMed,10.1007/s12275-022-1448-x,J Microbiol. 2022 Feb;60(2):224-233,b.kim@ewha.ac.kr,PlpA-defective V. vulnificus significantly augmented host cell blebbing.,C Cho 2022,2022,3 genes,Cho-2022-Vibrio vulnificus PlpA facilitates ne,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19552,PHI:12034,UniProt,C3VHN8,GenBank,ACP30470,,,CKUH,vvpE,,,,,,PHI:12035; PHI:12036,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),3T3-L1,,,3T3-L1 cell,neutral metalloproteinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35102528,PubMed,10.1007/s12275-022-1448-x,J Microbiol. 2022 Feb;60(2):224-233,b.kim@ewha.ac.kr,PlpA-defective V. vulnificus significantly augmented host cell blebbing.,C Cho 2022,2022,3 genes,Cho-2022-Vibrio vulnificus PlpA facilitates ne,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19553,PHI:12035,UniProt,P19247,GenBank,AAO07360,,,CMCP6,vvhA,chromosome II,,,,,PHI:12034; PHI:12036,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),3T3-L1,,,3T3-L1 cell,cytolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35102528,PubMed,10.1007/s12275-022-1448-x,J Microbiol. 2022 Feb;60(2):224-233,b.kim@ewha.ac.kr,PlpA-defective V. vulnificus significantly augmented host cell blebbing.,C Cho 2022,2022,3 genes,Cho-2022-Vibrio vulnificus PlpA facilitates ne,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19554,PHI:12036,UniProt,no data found,GenBank,,,,,plpA,,,,,,PHI:12034; PHI:12035,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,rodents,10090,Mus musculus (related: house mouse),3T3-L1,,,3T3-L1 cell,phospholipase A2,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35102528,PubMed,10.1007/s12275-022-1448-x,J Microbiol. 2022 Feb;60(2):224-233,b.kim@ewha.ac.kr,PlpA-defective V. vulnificus significantly augmented host cell blebbing.,C Cho 2022,2022,3 genes,Cho-2022-Vibrio vulnificus PlpA facilitates ne,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19555,PHI:12034,UniProt,C3VHN8,GenBank,ACP30470,,,CKUH,vvpE,,,,,,PHI:12035,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,neutral metalloproteinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35102528,PubMed,10.1007/s12275-022-1448-x,J Microbiol. 2022 Feb;60(2):224-233,b.kim@ewha.ac.kr,PlpA-defective V. vulnificus significantly augmented host cell blebbing.,C Cho 2022,2022,3 genes,Cho-2022-Vibrio vulnificus PlpA facilitates ne,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19556,PHI:12035,UniProt,P19247,GenBank,AAO07360,,,CMCP6,vvhA,chromosome II,,,,,PHI:12034,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,cytolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35102528,PubMed,10.1007/s12275-022-1448-x,J Microbiol. 2022 Feb;60(2):224-233,b.kim@ewha.ac.kr,PlpA-defective V. vulnificus significantly augmented host cell blebbing.,C Cho 2022,2022,3 genes,Cho-2022-Vibrio vulnificus PlpA facilitates ne,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19557,PHI:12034,UniProt,C3VHN8,GenBank,ACP30470,,,CKUH,vvpE,,,,,,PHI:12035; PHI:12036,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,neutral metalloproteinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35102528,PubMed,10.1007/s12275-022-1448-x,J Microbiol. 2022 Feb;60(2):224-233,b.kim@ewha.ac.kr,PlpA-defective V. vulnificus significantly augmented host cell blebbing.,C Cho 2022,2022,3 genes,Cho-2022-Vibrio vulnificus PlpA facilitates ne,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19558,PHI:12035,UniProt,P19247,GenBank,AAO07360,,,CMCP6,vvhA,chromosome II,,,,,PHI:12034; PHI:12036,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,cytolysin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35102528,PubMed,10.1007/s12275-022-1448-x,J Microbiol. 2022 Feb;60(2):224-233,b.kim@ewha.ac.kr,PlpA-defective V. vulnificus significantly augmented host cell blebbing.,C Cho 2022,2022,3 genes,Cho-2022-Vibrio vulnificus PlpA facilitates ne,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19559,PHI:12036,UniProt,no data found,GenBank,,,,,plpA,,,,,,PHI:12034; PHI:12035,672,Vibrio vulnificus,914127,MO6-24/O,vibriosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,phospholipase A2,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35102528,PubMed,10.1007/s12275-022-1448-x,J Microbiol. 2022 Feb;60(2):224-233,b.kim@ewha.ac.kr,PlpA-defective V. vulnificus significantly augmented host cell blebbing.,C Cho 2022,2022,3 genes,Cho-2022-Vibrio vulnificus PlpA facilitates ne,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19560,PHI:12037,UniProt,A0A0H3PCP5,GenBank,EAQ72030,,,81-176,cdtC,,,,,,,197,Campylobacter jejuni,354242,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,"cytolethal distending toxin, subunit C",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; heterologous gene complementation,,,YVS,35096652,PubMed,10.3389/fcimb.2021.803730,Front Cell Infect Microbiol. 2022 Jan 13;11:803730,srd@bmb.sdu.dk,Inactivation of cdtC and mlaEFD decreased the virulence of C. jejuni.,A Sałamaszyńska-Guz 2021,2021,4 genes,Salamaszynska-G-2021-Campylobacter jejuni Viru,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19561,PHI:12038,UniProt,A0A649QZH5,GenBank,VTX84158,,,Campylobacter_jejuni_BgEED08,mlaE,,,,,,PHI:12039; PHI:12040,197,Campylobacter jejuni,354242,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,putative phospholipid ABC transporter permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35096652,PubMed,10.3389/fcimb.2021.803730,Front Cell Infect Microbiol. 2022 Jan 13;11:803730,srd@bmb.sdu.dk,Inactivation of cdtC and mlaEFD decreased the virulence of C. jejuni.,A Sałamaszyńska-Guz 2021,2021,4 genes,Salamaszynska-G-2021-Campylobacter jejuni Viru,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19562,PHI:12039,,no data found,GenBank,AWB41137,,,12567,mlaF,,,,,,PHI:12038; PHI:12040,197,Campylobacter jejuni,354242,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,"lipid asymmetry ABC transporter MlaABCDEF, ATPase component",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35096652,PubMed,10.3389/fcimb.2021.803730,Front Cell Infect Microbiol. 2022 Jan 13;11:803730,srd@bmb.sdu.dk,Inactivation of cdtC and mlaEFD decreased the virulence of C. jejuni.,A Sałamaszyńska-Guz 2021,2021,4 genes,Salamaszynska-G-2021-Campylobacter jejuni Viru,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19563,PHI:12040,,no data found,GenBank,AWB41138,,,12567,mlaD,,,,,,PHI:12038; PHI:12039,197,Campylobacter jejuni,354242,81-176,gastroenteritis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,"lipid asymmetry ABC transporter MlaABCDEF, periplasmic component",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35096652,PubMed,10.3389/fcimb.2021.803730,Front Cell Infect Microbiol. 2022 Jan 13;11:803730,srd@bmb.sdu.dk,Inactivation of cdtC and mlaEFD decreased the virulence of C. jejuni.,A Sałamaszyńska-Guz 2021,2021,4 genes,Salamaszynska-G-2021-Campylobacter jejuni Viru,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19564,PHI:12041,UniProt,K3W372,GenBank,EKJ78895,,,CS3096,FpHtf3 (FPSE_00937),,,,,,,101028,Fusarium pseudograminearum,,WZ2-8,Fusarium crown rot,monocots,4565,Triticum aestivum (related: bread wheat),cv. Aikang 58,,,coleoptile; spikelet,homeobox family protein,,,,reduced virulence,,,,yes,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35064361,PubMed,10.1007/s10528-021-10150-y,Biochem Genet. 2022 Jan 22,llchenaky@163.com,Deletion of FpHtf3 significantly attenuated F. pseudograminearum virulence in wheat.,Y Ma 2022,2022,1 gene,Ma-2022-Identification and Characterization of,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19565,PHI:12042,UniProt,Q46877,GenBank,AAC75752,,,K-12,norV,,,,,,,562,Escherichia coli,544404,TW14359,infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,nitric oxide (NO) reductase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,35056555,PubMed,10.3390/microorganisms10010106,Microorganisms. 2022 Jan 5;10(1):106,mkorir@aurora.edu,"NO enhanced virulence by inducing Stx2 production in TW14359, and that toxin production was inhibited by NorV encoded by a gene found in most clade 8 strains.",R A Safadi 2022,2022,1 gene,Al Safadi-2022-Nitric Oxide Induced stx2 Expre,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19566,PHI:12043,UniProt,S7W0F4,GenBank,EPR60584,,,GT1,PFK1 (TGGT1_240890),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,probable ATP-dependent 6-phosphofructokinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35104280,PubMed,10.1371/journal.ppat.1010293,PLoS Pathog. 2022 Feb 1;18(2):e1010293,shenbang@mail.hzau.edu.cn,"Only PPi-PFK was indispensable for parasite growth, whereas the deletion of ATP-PFK did not affect parasite proliferation or virulence.",X Yang 2022,2022,2 genes,Yang-2022-Essential role of pyrophosphate home,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19567,PHI:12044,UniProt,A0A125YKV5,GenBank,EPR62328,,,GT1,PFK2 (TGGT1_226960),,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,pyrophosphate--fructose 6-phosphate 1-phosphotransferase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35104280,PubMed,10.1371/journal.ppat.1010293,PLoS Pathog. 2022 Feb 1;18(2):e1010293,shenbang@mail.hzau.edu.cn,"Only PPi-PFK was indispensable for parasite growth, whereas the deletion of ATP-PFK did not affect parasite proliferation or virulence.",X Yang 2022,2022,2 genes,Yang-2022-Essential role of pyrophosphate home,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19568,PHI:12045,UniProt,O24885,GenBank,AAD07112,,,26695,HP0044,,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,GDP-D-mannose dehydratase,,,,reduced virulence,,,,,,,,reduced,,no,SDS; novobiocin,SDS: CHEBI:8984; novobiocin: CHEBI:28368,,,,,gene deletion: full; gene complementation,,,YVS,35052824,PubMed,10.3390/biomedicines10010145,Biomedicines. 2022 Jan 10;10(1):145,mckao@life.nthu.edu.tw,"LPS-defective mutants also had significantly reduced bacterial infection, adhesion and internalization in the in vitro cell line model.",A N Liu 2022,2022,2 genes,Liu-2022-The Effects of HP0044 and HP1275 Knoc,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19569,PHI:12046,UniProt,O25865,GenBank,AAD08319,,,26695,HP1275,,,,,,,210,Helicobacter pylori,85962,26695,gastric infection,primates,9606,Homo sapiens (related: human),AGS cell line,,,gastric epithelium cell line,phosphomannomutase (PMM)/phosphoglucomutase (PGM),,,,reduced virulence,,,,,,,,reduced,,no,SDS; novobiocin,SDS: CHEBI:8984; novobiocin: CHEBI:28368,,,,,gene deletion: full; gene complementation,,,YVS,35052824,PubMed,10.3390/biomedicines10010145,Biomedicines. 2022 Jan 10;10(1):145,mckao@life.nthu.edu.tw,"LPS-defective mutants also had significantly reduced bacterial infection, adhesion and internalization in the in vitro cell line model.",A N Liu 2022,2022,2 genes,Liu-2022-The Effects of HP0044 and HP1275 Knoc,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19570,PHI:12047,UniProt,A0A8E5JM30,GenBank,QUZ94265,,,607307-2,acrD,,,,,,,28901,Salmonella enterica,,serovar Enteritidis strain SJTUF10978,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,resistance-nodulation-cell division (RND) transporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35010216,PubMed,10.3390/foods11010090,Foods. 2021 Dec 30;11(1):90,xmshi@sjtu.edu.cn,The invasion ability of S. Enteritidis was influenced by egg white for the cells lacking acrD.,X Qin 2021,2021,1 gene,Qin-2021-Resistance-Nodulation-Cell Division (,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19571,PHI:12048,UniProt,A0A345Z9M0,GenBank,AXK59706,,,Psa743,hopAU1,,,,,,,317,Pseudomonas syringae,1108972,pv. actinidiae strain M228,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),cv. Hongyang,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35008934,PubMed,10.3390/ijms23010508,Int J Mol Sci. 2022 Jan 3;23(1):508,huanglili@nwsuaf.edu.cn,The virulence assays of the lesion areas did not reveal any significant differences between M228 and ΔHopAU1 on kiwifruit leaf discs.,J Zhang 2022,2022,1 gene,Zhang-2022-Pseudomonas syringae pv. actinidiae,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19572,PHI:12048,UniProt,A0A345Z9M0,GenBank,AXK59706,,,Psa743,hopAU1,,,,,,,317,Pseudomonas syringae,1108972,pv. actinidiae strain M228,bacterial canker,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,YVS,35008934,PubMed,10.3390/ijms23010508,Int J Mol Sci. 2022 Jan 3;23(1):508,huanglili@nwsuaf.edu.cn,The virulence assays of the lesion areas did not reveal any significant differences between M228 and ΔHopAU1 on kiwifruit leaf discs.,J Zhang 2022,2022,1 gene,Zhang-2022-Pseudomonas syringae pv. actinidiae,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19573,PHI:12049,UniProt,P75825,GenBank,AAC73960,,,K-12,hcp,,,,,,,562,Escherichia coli,,APEC O18,colibacillosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX3,,,,hydroxylamine reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35003930,PubMed,10.7717/peerj.12631,PeerJ. 2021 Dec 17;9:e12631,Catherine.Logue@uga.edu,"Deletion of hcp reduced resistance of APECO18 to predation by D. discoideum, suggesting that T6SS was involved in the virulence of APECO18.",A L de Oliveira 2021,2021,4 genes,de Oliveira-2021-Characterizing the Type 6 Sec,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19574,PHI:12050,UniProt,Q8X7V4,GenBank,BAB33647,,,Sakai,impK,,,,,,,562,Escherichia coli,,APEC O18,colibacillosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX3,,,,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35003930,PubMed,10.7717/peerj.12631,PeerJ. 2021 Dec 17;9:e12631,Catherine.Logue@uga.edu,"Deletion of hcp reduced resistance of APECO18 to predation by D. discoideum, suggesting that T6SS was involved in the virulence of APECO18.",A L de Oliveira 2021,2021,4 genes,de Oliveira-2021-Characterizing the Type 6 Sec,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19575,PHI:12051,UniProt,A0A069FIK9,GenBank,ARR32081,,,5CRE51,evpB,,,,,,,562,Escherichia coli,,APEC O18,colibacillosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX3,,,,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35003930,PubMed,10.7717/peerj.12631,PeerJ. 2021 Dec 17;9:e12631,Catherine.Logue@uga.edu,"Deletion of hcp reduced resistance of APECO18 to predation by D. discoideum, suggesting that T6SS was involved in the virulence of APECO18.",A L de Oliveira 2021,2021,4 genes,de Oliveira-2021-Characterizing the Type 6 Sec,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19576,PHI:12052,UniProt,A0A0L7AFE5,GenBank,OTE56952,,,OLC1269,icmF,,,,,,,562,Escherichia coli,,APEC O18,colibacillosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX3,,,,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35003930,PubMed,10.7717/peerj.12631,PeerJ. 2021 Dec 17;9:e12631,Catherine.Logue@uga.edu,"Deletion of hcp reduced resistance of APECO18 to predation by D. discoideum, suggesting that T6SS was involved in the virulence of APECO18.",A L de Oliveira 2021,2021,4 genes,de Oliveira-2021-Characterizing the Type 6 Sec,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19577,PHI:12049,UniProt,P75825,GenBank,AAC73960,,,K-12,hcp,,,,,,,562,Escherichia coli,,APEC O18,colibacillosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX3,,,,hydroxylamine reductase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35003930,PubMed,10.7717/peerj.12631,PeerJ. 2021 Dec 17;9:e12631,Catherine.Logue@uga.edu,Deletion of the aforementioned genes did not significantly affect adherence and invasion capabilities of APECO18.,A L de Oliveira 2021,2021,4 genes,de Oliveira-2021-Characterizing the Type 6 Sec,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19578,PHI:12050,UniProt,Q8X7V4,GenBank,BAB33647,,,Sakai,impK,,,,,,,562,Escherichia coli,,APEC O18,colibacillosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX3,,,,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35003930,PubMed,10.7717/peerj.12631,PeerJ. 2021 Dec 17;9:e12631,Catherine.Logue@uga.edu,Deletion of the aforementioned genes did not significantly affect adherence and invasion capabilities of APECO18.,A L de Oliveira 2021,2021,4 genes,de Oliveira-2021-Characterizing the Type 6 Sec,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19579,PHI:12051,UniProt,A0A069FIK9,GenBank,ARR32081,,,5CRE51,evpB,,,,,,,562,Escherichia coli,,APEC O18,colibacillosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX3,,,,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35003930,PubMed,10.7717/peerj.12631,PeerJ. 2021 Dec 17;9:e12631,Catherine.Logue@uga.edu,Deletion of the aforementioned genes did not significantly affect adherence and invasion capabilities of APECO18.,A L de Oliveira 2021,2021,4 genes,de Oliveira-2021-Characterizing the Type 6 Sec,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19580,PHI:12052,UniProt,A0A0L7AFE5,GenBank,OTE56952,,,OLC1269,icmF,,,,,,,562,Escherichia coli,,APEC O18,colibacillosis,eukaryotes,44689,Dictyostelium discoideum (related: amoeba),AX3,,,,type VI secretion system protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35003930,PubMed,10.7717/peerj.12631,PeerJ. 2021 Dec 17;9:e12631,Catherine.Logue@uga.edu,Deletion of the aforementioned genes did not significantly affect adherence and invasion capabilities of APECO18.,A L de Oliveira 2021,2021,4 genes,de Oliveira-2021-Characterizing the Type 6 Sec,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19581,PHI:12053,UniProt,K3VB50,GenBank,EKJ69468,,,CS3096,Fpkapc (FPSE_10348),,,,,,,101028,Fusarium pseudograminearum,,WZ2-8A,Fusarium crown rot; Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,coleoptile,bZip transcription factor,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,aberrant,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35000433,PubMed,10.1094/PHYTO-12-21-0520-R,Phytopathology. 2022 Jan 9,llchensky@163.com,Fpkapc was required for full virulence in F. pseudograminearum.,J Zhao 2022,2022,1 gene,Zhao-2022-Transcriptome analysis and functiona,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19582,PHI:12053,UniProt,K3VB50,GenBank,EKJ69468,,,CS3096,Fpkapc (FPSE_10348),,,,,,,101028,Fusarium pseudograminearum,,WZ2-8A,Fusarium crown rot; Fusarium head blight,monocots,4513,Hordeum vulgare (related: barley),,,,leaf,bZip transcription factor,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,aberrant,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35000433,PubMed,10.1094/PHYTO-12-21-0520-R,Phytopathology. 2022 Jan 9,llchensky@163.com,Fpkapc was required for full virulence in F. pseudograminearum.,J Zhao 2022,2022,1 gene,Zhao-2022-Transcriptome analysis and functiona,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19583,PHI:12054,UniProt,G4NGD2,GenBank,EHA47089,,,70-15,MoPL1 (MGG_04348),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Ingrid,,,leaf,secreted pectate lyase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34964944,PubMed,10.1007/s12275-022-1074-7,J Microbiol. 2022 Jan;60(1):79-88,schaffrath@bio3.rwth-aachen.de,"The enzymatic activity of MoPl1 was responsible for diminished virulence, which was presumably due to degradation products recognized as danger associated molecular patterns (DAMPs), which strengthen the plant immune response.",A Wegner 2022,2022,1 gene,Wegner-2022-Gene deletion and constitutive exp,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19584,PHI:12054,UniProt,G4NGD2,GenBank,EHA47089,,,70-15,MoPL1 (MGG_04348),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Ingrid,,,leaf,secreted pectate lyase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,other evidence: constitutive expression,,,YVS,34964944,PubMed,10.1007/s12275-022-1074-7,J Microbiol. 2022 Jan;60(1):79-88,schaffrath@bio3.rwth-aachen.de,"The enzymatic activity of MoPl1 was responsible for diminished virulence, which was presumably due to degradation products recognized as danger associated molecular patterns (DAMPs), which strengthen the plant immune response.",A Wegner 2022,2022,1 gene,Wegner-2022-Gene deletion and constitutive exp,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19585,PHI:12055,,no data found,GenBank,AAZ52094,,,MGAS5005,M5005_Spy_1476 (SP-TyK),,,,,,,1314,Streptococcus pyogenes,,serotype M1T1 strain 5448,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,non-canonical tyrosine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34950110,PubMed,10.3389/fmicb.2021.689246,Front Microbiol. 2021 Dec 7;12:689246,vijay.pancholi@osumc.edu,"The mutant displayed sustained release of IL-6 compared to TNF-a during coculturing with A549 lung cell lines, attenuation in mice sepsis model, and significantly reduced ability to adhere to and invade A549 lung cells.",S Kant 2021,2021,1 gene,Kant-2021-Novel Tyrosine Kinase-Mediated Phosp,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19586,PHI:12055,,no data found,GenBank,AAZ52094,,,MGAS5005,M5005_Spy_1476 (SP-TyK),,,,,,,1314,Streptococcus pyogenes,,serotype M1T1 strain 5448,necrotizing fasciitis; streptococcal toxic shock syndrome; necrotic skin lesions,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,non-canonical tyrosine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34950110,PubMed,10.3389/fmicb.2021.689246,Front Microbiol. 2021 Dec 7;12:689246,vijay.pancholi@osumc.edu,"The mutant displayed sustained release of IL-6 compared to TNF-a during coculturing with A549 lung cell lines, attenuation in mice sepsis model, and significantly reduced ability to adhere to and invade A549 lung cells.",S Kant 2021,2021,1 gene,Kant-2021-Novel Tyrosine Kinase-Mediated Phosp,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19587,PHI:12056,UniProt,A0A3S4U6W9,GenBank,VEG61670,,,NCTC11951,cjdsbA1,chromosome 1,,,,,,197,Campylobacter jejuni,407148,81116,gastroenteritis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,periplasmic oxidoreductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34948248,PubMed,10.3390/ijms222413451,Int J Mol Sci. 2021 Dec 15;22(24):13451,kjkryn@gmail.com,The inactivation of the Dsb oxidative system caused a decreased C. jejuni virulence in the Galleria model.,A M Banaś 2021,2021,2 genes,"Banas-2021-Interplay between DsbA1, DsbA2 and",BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19588,PHI:12057,,no data found,GenBank,ABV52896,,,81116; NCTC 11828,c8j_1298,,,,,,,197,Campylobacter jejuni,407148,81116,gastroenteritis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,periplasmic oxidoreductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34948248,PubMed,10.3390/ijms222413451,Int J Mol Sci. 2021 Dec 15;22(24):13451,kjkryn@gmail.com,The inactivation of the Dsb oxidative system caused a decreased C. jejuni virulence in the Galleria model.,A M Banaś 2021,2021,2 genes,"Banas-2021-Interplay between DsbA1, DsbA2 and",BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19589,PHI:12058,UniProt,A0A0D1C055,GenBank,KIS67322,,,521,xyn1 (UMAG_04422),chromosome 14,,,,,,5270,Ustilago maydis,,CL13,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,beta-xylanase,,,,reduced virulence,,,,,,,,,,no,dithiothreitol; NaCl; SDS; calcofluor white; tunicamycin; sorbitol,dithiothreitol: CHEBI:18320; NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; tunicamycin: CHEBI:29699; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34947062,PubMed,10.3390/jof7121081,J Fungi (Basel). 2021 Dec 15;7(12):1081,joibecor@upo.es,Ustilago maydis xylanases were differentially expressed during infection and are required for full virulence.,I Moreno-Sánchez 2021,2021,3 genes,Moreno-Sánchez-2021-Ustilago maydis Secreted E,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19590,PHI:12059,UniProt,Q4P902,GenBank,KIS68312,,,521,xyn2 (UMAG_03411),chromosome 9,,,,,,5270,Ustilago maydis,,CL13,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,"endo-1,4-beta-xylanase",,,,reduced virulence,,,,,,,,,,no,dithiothreitol; NaCl; SDS; calcofluor white; tunicamycin; sorbitol,dithiothreitol: CHEBI:18320; NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; tunicamycin: CHEBI:29699; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34947062,PubMed,10.3390/jof7121081,J Fungi (Basel). 2021 Dec 15;7(12):1081,joibecor@upo.es,Ustilago maydis xylanases were differentially expressed during infection and are required for full virulence.,I Moreno-Sánchez 2021,2021,3 genes,Moreno-Sánchez-2021-Ustilago maydis Secreted E,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19591,PHI:12060,UniProt,Q4P0L3,GenBank,KIS70264,,,521,xyn11 (UMAG_06350),chromosome 4,,,,,,5270,Ustilago maydis,,CL13,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,"endo-1,4-beta-xylanase",,,,reduced virulence,,,,,,,,,,no,dithiothreitol; NaCl; SDS; calcofluor white; tunicamycin; sorbitol,dithiothreitol: CHEBI:18320; NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; tunicamycin: CHEBI:29699; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34947062,PubMed,10.3390/jof7121081,J Fungi (Basel). 2021 Dec 15;7(12):1081,joibecor@upo.es,Ustilago maydis xylanases were differentially expressed during infection and are required for full virulence.,I Moreno-Sánchez 2021,2021,3 genes,Moreno-Sánchez-2021-Ustilago maydis Secreted E,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19592,PHI:12058,UniProt,A0A0D1C055,GenBank,KIS67322,,,521,xyn1 (UMAG_04422),chromosome 14,,,,,PHI:12059,5270,Ustilago maydis,,CL13,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,beta-xylanase,,,,reduced virulence,,,,,,,,,,no,dithiothreitol; NaCl; SDS; calcofluor white; tunicamycin; sorbitol,dithiothreitol: CHEBI:18320; NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; tunicamycin: CHEBI:29699; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34947062,PubMed,10.3390/jof7121081,J Fungi (Basel). 2021 Dec 15;7(12):1081,joibecor@upo.es,Ustilago maydis xylanases were differentially expressed during infection and are required for full virulence.,I Moreno-Sánchez 2021,2021,3 genes,Moreno-Sánchez-2021-Ustilago maydis Secreted E,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19593,PHI:12059,UniProt,Q4P902,GenBank,KIS68312,,,521,xyn2 (UMAG_03411),chromosome 9,,,,,PHI:12058,5270,Ustilago maydis,,CL13,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,"endo-1,4-beta-xylanase",,,,reduced virulence,,,,,,,,,,no,dithiothreitol; NaCl; SDS; calcofluor white; tunicamycin; sorbitol,dithiothreitol: CHEBI:18320; NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; tunicamycin: CHEBI:29699; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34947062,PubMed,10.3390/jof7121081,J Fungi (Basel). 2021 Dec 15;7(12):1081,joibecor@upo.es,Ustilago maydis xylanases were differentially expressed during infection and are required for full virulence.,I Moreno-Sánchez 2021,2021,3 genes,Moreno-Sánchez-2021-Ustilago maydis Secreted E,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19594,PHI:12058,UniProt,A0A0D1C055,GenBank,KIS67322,,,521,xyn1 (UMAG_04422),chromosome 14,,,,,PHI:12059; PHI:12060,5270,Ustilago maydis,,CL13,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,beta-xylanase,,,,reduced virulence,,,,,,,,,,no,dithiothreitol; NaCl; SDS; calcofluor white; tunicamycin; sorbitol,dithiothreitol: CHEBI:18320; NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; tunicamycin: CHEBI:29699; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34947062,PubMed,10.3390/jof7121081,J Fungi (Basel). 2021 Dec 15;7(12):1081,joibecor@upo.es,Ustilago maydis xylanases were differentially expressed during infection and are required for full virulence.,I Moreno-Sánchez 2021,2021,3 genes,Moreno-Sánchez-2021-Ustilago maydis Secreted E,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19595,PHI:12059,UniProt,Q4P902,GenBank,KIS68312,,,521,xyn2 (UMAG_03411),chromosome 9,,,,,PHI:12058; PHI:12060,5270,Ustilago maydis,,CL13,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,"endo-1,4-beta-xylanase",,,,reduced virulence,,,,,,,,,,no,dithiothreitol; NaCl; SDS; calcofluor white; tunicamycin; sorbitol,dithiothreitol: CHEBI:18320; NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; tunicamycin: CHEBI:29699; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34947062,PubMed,10.3390/jof7121081,J Fungi (Basel). 2021 Dec 15;7(12):1081,joibecor@upo.es,Ustilago maydis xylanases were differentially expressed during infection and are required for full virulence.,I Moreno-Sánchez 2021,2021,3 genes,Moreno-Sánchez-2021-Ustilago maydis Secreted E,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19596,PHI:12060,UniProt,Q4P0L3,GenBank,KIS70264,,,521,xyn11 (UMAG_06350),chromosome 4,,,,,PHI:12058; PHI:12059,5270,Ustilago maydis,,CL13,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,"endo-1,4-beta-xylanase",,,,reduced virulence,,,,,,,,,,no,dithiothreitol; NaCl; SDS; calcofluor white; tunicamycin; sorbitol,dithiothreitol: CHEBI:18320; NaCl: CHEBI:26710; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; tunicamycin: CHEBI:29699; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,YVS,34947062,PubMed,10.3390/jof7121081,J Fungi (Basel). 2021 Dec 15;7(12):1081,joibecor@upo.es,Ustilago maydis xylanases were differentially expressed during infection and are required for full virulence.,I Moreno-Sánchez 2021,2021,3 genes,Moreno-Sánchez-2021-Ustilago maydis Secreted E,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19597,PHI:12061,,no data found,GenBank,OWY57112,,,Z7,AaAreA,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,GATA transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,,no,cumyl hydroperoxide; tert-butyl-hydroperoxide; Congo red; CuSO4; KCl; NaCl; diethyl maleate,cumyl hydroperoxide: CHEBI:78673; tert-butyl-hydroperoxide: CHEBI:64090; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; KCl: CHEBI:32588; NaCl: CHEBI:26710; diethyl maleate: CHEBI:68508,,,,,gene deletion: full; gene complementation,,,YVS,34946995,PubMed,10.3390/jof7121013,J Fungi (Basel). 2021 Nov 26;7(12):1013,hyli@zju.edu.cn,"Pathogenicity assays assessed on detached citrus leaves revealed that mutations of AaAreA, AaLreA, AaLreB, or AaNsdD significantly decreased the fungal virulence.",Y Chen 2021,2021,6 genes,Chen-2021-Genome-Wide Identification and Funct,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19598,PHI:12062,,no data found,GenBank,OWY51034,,,Z7,AaAreB,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,GATA transcription factor,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,cumyl hydroperoxide; tert-butyl-hydroperoxide; Congo red; CuSO4; KCl; NaCl; diethyl maleate,cumyl hydroperoxide: CHEBI:78673; tert-butyl-hydroperoxide: CHEBI:64090; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; KCl: CHEBI:32588; NaCl: CHEBI:26710; diethyl maleate: CHEBI:68508,,,,,gene deletion: full; gene complementation,,,YVS,34946995,PubMed,10.3390/jof7121013,J Fungi (Basel). 2021 Nov 26;7(12):1013,hyli@zju.edu.cn,"Pathogenicity assays assessed on detached citrus leaves revealed that mutations of AaAreA, AaLreA, AaLreB, or AaNsdD significantly decreased the fungal virulence.",Y Chen 2021,2021,6 genes,Chen-2021-Genome-Wide Identification and Funct,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19599,PHI:12063,,no data found,GenBank,OWY45364,,,Z7,AaNsdD,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,GATA transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,,no,cumyl hydroperoxide; tert-butyl-hydroperoxide; Congo red; CuSO4; KCl; NaCl; diethyl maleate,cumyl hydroperoxide: CHEBI:78673; tert-butyl-hydroperoxide: CHEBI:64090; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; KCl: CHEBI:32588; NaCl: CHEBI:26710; diethyl maleate: CHEBI:68508,,,,,gene deletion: full; gene complementation,,,YVS,34946995,PubMed,10.3390/jof7121013,J Fungi (Basel). 2021 Nov 26;7(12):1013,hyli@zju.edu.cn,"Pathogenicity assays assessed on detached citrus leaves revealed that mutations of AaAreA, AaLreA, AaLreB, or AaNsdD significantly decreased the fungal virulence.",Y Chen 2021,2021,6 genes,Chen-2021-Genome-Wide Identification and Funct,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19600,PHI:12064,,no data found,GenBank,OWY58354,,,Z7,AaSreA,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,GATA transcription factor,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,cumyl hydroperoxide; tert-butyl-hydroperoxide; Congo red; CuSO4; KCl; NaCl; diethyl maleate,cumyl hydroperoxide: CHEBI:78673; tert-butyl-hydroperoxide: CHEBI:64090; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; KCl: CHEBI:32588; NaCl: CHEBI:26710; diethyl maleate: CHEBI:68508,,,,,gene deletion: full; gene complementation,,,YVS,34946995,PubMed,10.3390/jof7121013,J Fungi (Basel). 2021 Nov 26;7(12):1013,hyli@zju.edu.cn,"Pathogenicity assays assessed on detached citrus leaves revealed that mutations of AaAreA, AaLreA, AaLreB, or AaNsdD significantly decreased the fungal virulence.",Y Chen 2021,2021,6 genes,Chen-2021-Genome-Wide Identification and Funct,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19601,PHI:12065,,no data found,GenBank,OWY43847,,,Z7,AaLreB,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,GATA transcription factor,,,,reduced virulence,,,,,,reduced,,reduced,,no,cumyl hydroperoxide; tert-butyl-hydroperoxide; Congo red; CuSO4; KCl; NaCl; diethyl maleate,cumyl hydroperoxide: CHEBI:78673; tert-butyl-hydroperoxide: CHEBI:64090; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; KCl: CHEBI:32588; NaCl: CHEBI:26710; diethyl maleate: CHEBI:68508,,,,,gene deletion: full; gene complementation,,,YVS,34946995,PubMed,10.3390/jof7121013,J Fungi (Basel). 2021 Nov 26;7(12):1013,hyli@zju.edu.cn,"Pathogenicity assays assessed on detached citrus leaves revealed that mutations of AaAreA, AaLreA, AaLreB, or AaNsdD significantly decreased the fungal virulence.",Y Chen 2021,2021,6 genes,Chen-2021-Genome-Wide Identification and Funct,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19602,PHI:12066,,no data found,GenBank,OWY44150,,,Z7,AaLreA,,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Hongjv,,,leaf,GATA transcription factor,,,,reduced virulence,,,,,,wild type,,wild type,,no,cumyl hydroperoxide; tert-butyl-hydroperoxide; Congo red; CuSO4; KCl; NaCl; diethyl maleate,cumyl hydroperoxide: CHEBI:78673; tert-butyl-hydroperoxide: CHEBI:64090; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; KCl: CHEBI:32588; NaCl: CHEBI:26710; diethyl maleate: CHEBI:68508,,,,,gene deletion: full; gene complementation,,,YVS,34946995,PubMed,10.3390/jof7121013,J Fungi (Basel). 2021 Nov 26;7(12):1013,hyli@zju.edu.cn,"Pathogenicity assays assessed on detached citrus leaves revealed that mutations of AaAreA, AaLreA, AaLreB, or AaNsdD significantly decreased the fungal virulence.",Y Chen 2021,2021,6 genes,Chen-2021-Genome-Wide Identification and Funct,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19603,PHI:12067,UniProt,W5WTG3,GenBank,CYX81417,,,SS999,stp,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,ser/Thr phosphatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34946045,PubMed,10.3390/microorganisms9122442,Microorganisms. 2021 Nov 26;9(12):2442,rzhou@mail.hzau.edu.cn,"In comparison, stp deletion resulted in reduced impact compared to the stk deletion on impairing the virulence of S. suis.",Q Hu 2021,2021,2 genes,"Hu-2021-Comparative Phenotypic, Proteomic, and",BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19604,PHI:12068,UniProt,R9RJ65,GenBank,AGM49306,,,SS2-1,stk,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,ser/Thr protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34946045,PubMed,10.3390/microorganisms9122442,Microorganisms. 2021 Nov 26;9(12):2442,rzhou@mail.hzau.edu.cn,"In comparison, stp deletion resulted in reduced impact compared to the stk deletion on impairing the virulence of S. suis.",Q Hu 2021,2021,2 genes,"Hu-2021-Comparative Phenotypic, Proteomic, and",BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19605,PHI:12067,UniProt,W5WTG3,GenBank,CYX81417,,,SS999,stp,,,,,,PHI:12068,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,ser/Thr phosphatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34946045,PubMed,10.3390/microorganisms9122442,Microorganisms. 2021 Nov 26;9(12):2442,rzhou@mail.hzau.edu.cn,"In comparison, stp deletion resulted in reduced impact compared to the stk deletion on impairing the virulence of S. suis.",Q Hu 2021,2021,2 genes,"Hu-2021-Comparative Phenotypic, Proteomic, and",BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19606,PHI:12068,UniProt,R9RJ65,GenBank,AGM49306,,,SS2-1,stk,,,,,,PHI:12067,1307,Streptococcus suis,,SC19,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen,ser/Thr protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34946045,PubMed,10.3390/microorganisms9122442,Microorganisms. 2021 Nov 26;9(12):2442,rzhou@mail.hzau.edu.cn,"In comparison, stp deletion resulted in reduced impact compared to the stk deletion on impairing the virulence of S. suis.",Q Hu 2021,2021,2 genes,"Hu-2021-Comparative Phenotypic, Proteomic, and",BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19607,PHI:12069,UniProt,Q8P6N1,GenBank,AAM42208,,,ATCC 33913,relA,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish) cv. Japan 501,,,leaf,ATP:GTP 3'-pyrophosphotranferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34935430,PubMed,10.1128/spectrum.02057-21,Microbiol Spectr. 2021 Dec 22;9(3):e0205721,luolaixin@cau.edu.cn,The expression of spoT was of much greater importance than that of relA in the pathogenicity of Xcc.,K Bai 2021,2021,2 genes,Bai-2021-The Role of RelA and SpoT on ppGpp Pr,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19608,PHI:12070,UniProt,Q8P5T8,GenBank,AAM42517,,,ATCC 33913,spoT,,,,,,PHI:12069,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish) cv. Japan 501,,,leaf,"guanosine-3',5'-bis(diphosphate) 3'-diphosphatase",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34935430,PubMed,10.1128/spectrum.02057-21,Microbiol Spectr. 2021 Dec 22;9(3):e0205721,luolaixin@cau.edu.cn,The expression of spoT was of much greater importance than that of relA in the pathogenicity of Xcc.,K Bai 2021,2021,2 genes,Bai-2021-The Role of RelA and SpoT on ppGpp Pr,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19609,PHI:12069,UniProt,Q8P6N1,GenBank,AAM42208,,,ATCC 33913,relA,,,,,,PHI:12070,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish) cv. Japan 501,,,leaf,ATP:GTP 3'-pyrophosphotranferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34935430,PubMed,10.1128/spectrum.02057-21,Microbiol Spectr. 2021 Dec 22;9(3):e0205721,luolaixin@cau.edu.cn,The expression of spoT was of much greater importance than that of relA in the pathogenicity of Xcc.,K Bai 2021,2021,2 genes,Bai-2021-The Role of RelA and SpoT on ppGpp Pr,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19610,PHI:12071,UniProt,A7EN30,GenBank,XP_001592488,,,1980,SsEmp24,,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold,eudicots,3708,Brassica napus (related: rape),,,,leaf,endosomal P24B protein,,,,reduced virulence,,,,,,,,reduced,,no,CuSO4; NaCl,CuSO4: CHEBI:23414; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,34933451,PubMed,10.1128/mBio.03173-21,mBio. 2021 Dec 21;12(6):e0317321,xueqiongxiao@mail.hzau.edu.cn,"ΔSsEmp24 mutant and ΔSsErv25 mutant displayed abnormal vegetative growth and sclerotium formation, were defective in infection cushion formation, and showed lower virulence on host plants.",C Xie 2021,2021,2 genes,Xie-2021-Early Secretory Pathway-Associated Pr,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19611,PHI:12072,UniProt,A7EYK4,GenBank,XP_001588872,,,1980,SsErv25,,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold,eudicots,3708,Brassica napus (related: rape),,,,leaf,GOLD domain-containing protein,,,,reduced virulence,,,,,,,,reduced,,no,CuSO4; NaCl,CuSO4: CHEBI:23414; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,34933451,PubMed,10.1128/mBio.03173-21,mBio. 2021 Dec 21;12(6):e0317321,xueqiongxiao@mail.hzau.edu.cn,"ΔSsEmp24 mutant and ΔSsErv25 mutant displayed abnormal vegetative growth and sclerotium formation, were defective in infection cushion formation, and showed lower virulence on host plants.",C Xie 2021,2021,2 genes,Xie-2021-Early Secretory Pathway-Associated Pr,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19612,PHI:12071,UniProt,A7EN30,GenBank,XP_001592488,,,1980,SsEmp24,,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold,eudicots,3847,Glycine max (related: soybean),,,,leaf,endosomal P24B protein,,,,reduced virulence,,,,,,,,reduced,,no,CuSO4; NaCl,CuSO4: CHEBI:23414; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,34933451,PubMed,10.1128/mBio.03173-21,mBio. 2021 Dec 21;12(6):e0317321,xueqiongxiao@mail.hzau.edu.cn,"ΔSsEmp24 mutant and ΔSsErv25 mutant displayed abnormal vegetative growth and sclerotium formation, were defective in infection cushion formation, and showed lower virulence on host plants.",C Xie 2021,2021,2 genes,Xie-2021-Early Secretory Pathway-Associated Pr,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19613,PHI:12072,UniProt,A7EYK4,GenBank,XP_001588872,,,1980,SsErv25,,,,,,,5180,Sclerotinia sclerotiorum,,Sunf-M,white mold,eudicots,3847,Glycine max (related: soybean),,,,leaf,GOLD domain-containing protein,,,,reduced virulence,,,,,,,,reduced,,no,CuSO4; NaCl,CuSO4: CHEBI:23414; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,YVS,34933451,PubMed,10.1128/mBio.03173-21,mBio. 2021 Dec 21;12(6):e0317321,xueqiongxiao@mail.hzau.edu.cn,"ΔSsEmp24 mutant and ΔSsErv25 mutant displayed abnormal vegetative growth and sclerotium formation, were defective in infection cushion formation, and showed lower virulence on host plants.",C Xie 2021,2021,2 genes,Xie-2021-Early Secretory Pathway-Associated Pr,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19614,PHI:12073,UniProt,A0A380DTK4,GenBank,SUK50673,,,NCTC5664,vWbp,,,,,,,1280,Staphylococcus aureus,,Newman D2C,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,secreted von willebrand factor-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,YVS,34931454,PubMed,10.1111/jcmm.17129,J Cell Mol Med. 2022 Feb;26(3):828-839,wangdc@jlu.edu.cn,There were no significant differences between the ΔvWbp group and the galangin treatment group establishing that galangin was a potent therapeutic agent against S. aureus- induced pneumonia.,Y Jin 2022,2022,1 gene,Jin-2022-Galangin as a direct inhibitor of vWb,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19615,PHI:12074,UniProt,A0A0H2YQR1,GenBank,ABG83208,,,ATCC 13124,nanI,,,,,,,1502,Clostridium perfringens,,F4969,gas gangrene (human); clostridial myonecrosis,primates,9606,Homo sapiens (related: human),HT29 cells,,,HEp-2 cell,sialidase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34908460,PubMed,10.1128/mSphere.00848-21,mSphere. 2021 Dec 22;6(6):e0084821,fauzal@ucdavis.edu,NanI had a proportionately greater potentiating effects on CPE-induced cytotoxicity for HT29 cells and MTX-E12 cells.,M A Navarro 2021,2021,1 gene,Navarro-2021-NanI Sialidase Enhances the Actio,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19616,PHI:12074,UniProt,A0A0H2YQR1,GenBank,ABG83208,,,ATCC 13124,nanI,,,,,,,1502,Clostridium perfringens,,F4969,gas gangrene (human); clostridial myonecrosis,primates,9606,Homo sapiens (related: human),HT29-MTX-E12 cells,,,epithelial cell,sialidase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34908460,PubMed,10.1128/mSphere.00848-21,mSphere. 2021 Dec 22;6(6):e0084821,fauzal@ucdavis.edu,NanI had a proportionately greater potentiating effects on CPE-induced cytotoxicity for HT29 cells and MTX-E12 cells.,M A Navarro 2021,2021,1 gene,Navarro-2021-NanI Sialidase Enhances the Actio,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19617,PHI:12074,UniProt,A0A0H2YQR1,GenBank,ABG83208,,,ATCC 13124,nanI,,,,,,,1502,Clostridium perfringens,,F4969,gas gangrene (human); clostridial myonecrosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,small intestine,sialidase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: purified protein,,,YVS,34908460,PubMed,10.1128/mSphere.00848-21,mSphere. 2021 Dec 22;6(6):e0084821,fauzal@ucdavis.edu,Co-treatment with NanI significantly increased intestinal damage caused by the moderate 50mg/mL CPE dose.,M A Navarro 2021,2021,1 gene,Navarro-2021-NanI Sialidase Enhances the Actio,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19618,PHI:12075,UniProt,A0A0H3MBD4,GenBank,CAP03628,,,434/Bu,InaC (CTL0184),,,,,,,813,Chlamydia trachomatis,,L2,urinary tract infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34903051,PubMed,10.1128/mBio.02397-21,mBio. 2021 Dec 21;12(6):e0239721,fabienne.paumet@jefferson.edu,"The chlamydial effector InaC activated Ras homolog family member A (RhoA) to control the formation of actin scaffolds around the inclusion, an event that was critical for inclusion stability. Furthermore",A Haines 2021,2021,1 gene,Haines-2021-Cross Talk between ARF1 and RhoA C,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19619,PHI:12076,UniProt,A0A0L0VA94,GenBank,KNE95904,,,,Pst_4,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,stem rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Fielder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,34890460,PubMed,10.1093/plphys/kiab434,Plant Physiol. 2021 Dec 4;187(4):2530-2543,wangxiaojie@nwsuaf.edu.cn,Knocking down Pst_4 and Pst_5 attenuated the virulence of Pst.,X Wang 2021,2021,2 genes,Wang-2021-Two stripe rust effectors impair whe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19620,PHI:12077,UniProt,A0A0L0VHJ5,GenBank,KNE98696,,,,Pst_5,,,,,,,27350,Puccinia striiformis,168172,f. sp. tritici,stem rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Fielder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,34890460,PubMed,10.1093/plphys/kiab434,Plant Physiol. 2021 Dec 4;187(4):2530-2543,wangxiaojie@nwsuaf.edu.cn,Knocking down Pst_4 and Pst_5 attenuated the virulence of Pst.,X Wang 2021,2021,2 genes,Wang-2021-Two stripe rust effectors impair whe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19621,PHI:12078,,no data found,,,,,,Pi04089,,,,,,,4787,Phytophthora infestans,,HB09-14-2,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. E-Potato 3,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,34886813,PubMed,10.1186/s12870-021-03364-0,BMC Plant Biol. 2021 Dec 9;21(1):582,tianzhd@mail.hzau.edu.cn,Potato plants stably expressing Pi04089 were more susceptible to P. infestans.,M Luo 2021,2021,1 gene,Luo-2021-Phytophthora infestans RXLR effector,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19622,PHI:12078,,no data found,,,,,,Pi04089,,,,,,,4787,Phytophthora infestans,,88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,34886813,PubMed,10.1186/s12870-021-03364-0,BMC Plant Biol. 2021 Dec 9;21(1):582,tianzhd@mail.hzau.edu.cn,Potato plants stably expressing Pi04089 were more susceptible to P. infestans.,M Luo 2021,2021,1 gene,Luo-2021-Phytophthora infestans RXLR effector,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19623,PHI:12079,,no data found,,,,,,casT,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,CRISPR/cas proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,YVS,34886764,PubMed,10.1080/21505594.2021.2007621,Virulence. 2021 Dec;12(1):3032-3044,hongtaizhang@aliyun.com,Cas6 deletion markedly attenuated virulence in a murine M. tuberculosis challenge model.,J Jiao 2021,2021,5 genes,Jiao-2021-M. tuberculosis CRISPR_Cas proteins,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19624,PHI:12080,UniProt,P9WPJ1,GenBank,CCP45624,,,H37Rv,cas6,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,CRISPR-associated endoribonuclease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34886764,PubMed,10.1080/21505594.2021.2007621,Virulence. 2021 Dec;12(1):3032-3044,hongtaizhang@aliyun.com,Cas6 deletion markedly attenuated virulence in a murine M. tuberculosis challenge model.,J Jiao 2021,2021,5 genes,Jiao-2021-M. tuberculosis CRISPR_Cas proteins,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19625,PHI:12081,UniProt,P9WJF5,GenBank,CCP45619,,,H37Rv,csm5,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen,CRISPR system cms protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34886764,PubMed,10.1080/21505594.2021.2007621,Virulence. 2021 Dec;12(1):3032-3044,hongtaizhang@aliyun.com,Cas6 deletion markedly attenuated virulence in a murine M. tuberculosis challenge model.,J Jiao 2021,2021,5 genes,Jiao-2021-M. tuberculosis CRISPR_Cas proteins,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19626,PHI:12082,UniProt,P71629,GenBank,CCP45623,,,H37Rv,csm1,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,CRISPR system single-strand-specific deoxyribonuclease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,34886764,PubMed,10.1080/21505594.2021.2007621,Virulence. 2021 Dec;12(1):3032-3044,hongtaizhang@aliyun.com,Recombinant MTBCas6 induced apoptosis of macrophages and lung fibroblasts.,J Jiao 2021,2021,5 genes,Jiao-2021-M. tuberculosis CRISPR_Cas proteins,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19627,PHI:12083,UniProt,P9WJF9,GenBank,CCP45621,,,H37Rv,csm3,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,CRISPR system cms endoribonuclease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,34886764,PubMed,10.1080/21505594.2021.2007621,Virulence. 2021 Dec;12(1):3032-3044,hongtaizhang@aliyun.com,Recombinant MTBCas6 induced apoptosis of macrophages and lung fibroblasts.,J Jiao 2021,2021,5 genes,Jiao-2021-M. tuberculosis CRISPR_Cas proteins,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19628,PHI:12080,UniProt,P9WPJ1,GenBank,CCP45624,,,H37Rv,cas6,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,CRISPR-associated endoribonuclease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,34886764,PubMed,10.1080/21505594.2021.2007621,Virulence. 2021 Dec;12(1):3032-3044,hongtaizhang@aliyun.com,Recombinant MTBCas6 induced apoptosis of macrophages and lung fibroblasts.,J Jiao 2021,2021,5 genes,Jiao-2021-M. tuberculosis CRISPR_Cas proteins,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19629,PHI:12080,UniProt,P9WPJ1,GenBank,CCP45624,,,H37Rv,cas6,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,CRISPR-associated endoribonuclease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,34886764,PubMed,10.1080/21505594.2021.2007621,Virulence. 2021 Dec;12(1):3032-3044,hongtaizhang@aliyun.com,Recombinant MTBCas6 induced apoptosis of macrophages and lung fibroblasts.,J Jiao 2021,2021,5 genes,Jiao-2021-M. tuberculosis CRISPR_Cas proteins,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19630,PHI:12080,UniProt,P9WPJ1,GenBank,CCP45624,,,H37Rv,cas6,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),L929 cell line,,,L-929 cell,CRISPR-associated endoribonuclease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,34886764,PubMed,10.1080/21505594.2021.2007621,Virulence. 2021 Dec;12(1):3032-3044,hongtaizhang@aliyun.com,Recombinant MTBCas6 induced apoptosis of macrophages and lung fibroblasts.,J Jiao 2021,2021,5 genes,Jiao-2021-M. tuberculosis CRISPR_Cas proteins,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19631,PHI:12080,UniProt,P9WPJ1,GenBank,CCP45624,,,H37Rv,cas6,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10036,Mesocricetus auratus (related: golden hamster),BHK-21 cell line,,,BHK-21 cell,CRISPR-associated endoribonuclease,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: recombinant protein,,,YVS,34886764,PubMed,10.1080/21505594.2021.2007621,Virulence. 2021 Dec;12(1):3032-3044,hongtaizhang@aliyun.com,Recombinant MTBCas6 induced apoptosis of macrophages and lung fibroblasts.,J Jiao 2021,2021,5 genes,Jiao-2021-M. tuberculosis CRISPR_Cas proteins,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19632,PHI:12084,UniProt,P33883,GenBank,AAA25875,,,PAO1,lasI,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,acyl-homoserine-lactone synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34884499,PubMed,10.3390/ijms222312699,Int J Mol Sci. 2021 Nov 24;22(23):12699,shenlx@nwu.edu.cn,"Wogonin attenuated the pathogenicity of the wild type strain, lasI deletion mutant, and rhlI deletion mutant, but not pqsA or pqsR single-gene deletion mutants, indicating that the pqs system played the dominant role during wogonin treatment.",S Wang 2021,2021,4 genes,Wang-2021-Inhibition of Virulence Factors and,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19633,PHI:12085,UniProt,P54291,GenBank,AAA89074,,,PAO1,rhlI,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,acyl-homoserine-lactone synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34884499,PubMed,10.3390/ijms222312699,Int J Mol Sci. 2021 Nov 24;22(23):12699,shenlx@nwu.edu.cn,"Wogonin attenuated the pathogenicity of the wild type strain, lasI deletion mutant, and rhlI deletion mutant, but not pqsA or pqsR single-gene deletion mutants, indicating that the pqs system played the dominant role during wogonin treatment.",S Wang 2021,2021,4 genes,Wang-2021-Inhibition of Virulence Factors and,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19634,PHI:12086,UniProt,Q9I4X3,GenBank,AE004532_9,,,PAO1,pqsA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,anthranilate--CoA ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34884499,PubMed,10.3390/ijms222312699,Int J Mol Sci. 2021 Nov 24;22(23):12699,shenlx@nwu.edu.cn,"Wogonin attenuated the pathogenicity of the wild type strain, lasI deletion mutant, and rhlI deletion mutant, but not pqsA or pqsR single-gene deletion mutants, indicating that the pqs system played the dominant role during wogonin treatment.",S Wang 2021,2021,4 genes,Wang-2021-Inhibition of Virulence Factors and,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19635,PHI:12087,UniProt,A0A7G9KWC2,GenBank,QNM80619,,,PAY,pqsR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,leaf,autoinducer synthesis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34884499,PubMed,10.3390/ijms222312699,Int J Mol Sci. 2021 Nov 24;22(23):12699,shenlx@nwu.edu.cn,"Wogonin attenuated the pathogenicity of the wild type strain, lasI deletion mutant, and rhlI deletion mutant, but not pqsA or pqsR single-gene deletion mutants, indicating that the pqs system played the dominant role during wogonin treatment.",S Wang 2021,2021,4 genes,Wang-2021-Inhibition of Virulence Factors and,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19636,PHI:12088,UniProt,Q9HYU4,GenBank,AE004752_3,,,PAO1,fadD1,,,,,,PHI:12089,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,long-chain-fatty-acid--CoA ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34867927,PubMed,10.3389/fmicb.2021.785112,Front Microbiol. 2021 Nov 16;12:785112,jesus.campos@umich.mx,"The fadD4 single mutant increased lethality compared to the PAO1 wild-type (WT) strain; however, the double mutants fadD1/fadD2, fadD1/fadD4, and fadD2/fadD4 and single mutant fadD2 increased worm survival.",L Martínez-Alcantar 2021,2021,3 genes,Martínez-Alcant-2021-Participation of Acyl-Coe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19637,PHI:12089,UniProt,Q9HYU3,GenBank,AE004752_4,,,PAO1,fadD2,,,,,,PHI:12088,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,long-chain-fatty-acid--CoA ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34867927,PubMed,10.3389/fmicb.2021.785112,Front Microbiol. 2021 Nov 16;12:785112,jesus.campos@umich.mx,"The fadD4 single mutant increased lethality compared to the PAO1 wild-type (WT) strain; however, the double mutants fadD1/fadD2, fadD1/fadD4, and fadD2/fadD4 and single mutant fadD2 increased worm survival.",L Martínez-Alcantar 2021,2021,3 genes,Martínez-Alcant-2021-Participation of Acyl-Coe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19638,PHI:12088,UniProt,Q9HYU4,GenBank,AE004752_3,,,PAO1,fadD1,,,,,,PHI:12090,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,long-chain-fatty-acid--CoA ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34867927,PubMed,10.3389/fmicb.2021.785112,Front Microbiol. 2021 Nov 16;12:785112,jesus.campos@umich.mx,"The fadD4 single mutant increased lethality compared to the PAO1 wild-type (WT) strain; however, the double mutants fadD1/fadD2, fadD1/fadD4, and fadD2/fadD4 and single mutant fadD2 increased worm survival.",L Martínez-Alcantar 2021,2021,3 genes,Martínez-Alcant-2021-Participation of Acyl-Coe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19639,PHI:12090,UniProt,A0A2C9WXX7,GenBank,OTI58916,,,S567_C10_BS,fadD4,,,,,,PHI:12088,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,long-chain-fatty-acid--CoA ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34867927,PubMed,10.3389/fmicb.2021.785112,Front Microbiol. 2021 Nov 16;12:785112,jesus.campos@umich.mx,"The fadD4 single mutant increased lethality compared to the PAO1 wild-type (WT) strain; however, the double mutants fadD1/fadD2, fadD1/fadD4, and fadD2/fadD4 and single mutant fadD2 increased worm survival.",L Martínez-Alcantar 2021,2021,3 genes,Martínez-Alcant-2021-Participation of Acyl-Coe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19640,PHI:12089,UniProt,Q9HYU3,GenBank,AE004752_4,,,PAO1,fadD2,,,,,,PHI:12090,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,long-chain-fatty-acid--CoA ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34867927,PubMed,10.3389/fmicb.2021.785112,Front Microbiol. 2021 Nov 16;12:785112,jesus.campos@umich.mx,"The fadD4 single mutant increased lethality compared to the PAO1 wild-type (WT) strain; however, the double mutants fadD1/fadD2, fadD1/fadD4, and fadD2/fadD4 and single mutant fadD2 increased worm survival.",L Martínez-Alcantar 2021,2021,3 genes,Martínez-Alcant-2021-Participation of Acyl-Coe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19641,PHI:12090,UniProt,A0A2C9WXX7,GenBank,OTI58916,,,S567_C10_BS,fadD4,,,,,,PHI:12089,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,long-chain-fatty-acid--CoA ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34867927,PubMed,10.3389/fmicb.2021.785112,Front Microbiol. 2021 Nov 16;12:785112,jesus.campos@umich.mx,"The fadD4 single mutant increased lethality compared to the PAO1 wild-type (WT) strain; however, the double mutants fadD1/fadD2, fadD1/fadD4, and fadD2/fadD4 and single mutant fadD2 increased worm survival.",L Martínez-Alcantar 2021,2021,3 genes,Martínez-Alcant-2021-Participation of Acyl-Coe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19642,PHI:12089,UniProt,Q9HYU3,GenBank,AE004752_4,,,PAO1,fadD2,,fadD2Tn,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,long-chain-fatty-acid--CoA ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34867927,PubMed,10.3389/fmicb.2021.785112,Front Microbiol. 2021 Nov 16;12:785112,jesus.campos@umich.mx,"The fadD4 single mutant increased lethality compared to the PAO1 wild-type (WT) strain; however, the double mutants fadD1/fadD2, fadD1/fadD4, and fadD2/fadD4 and single mutant fadD2 increased worm survival.",L Martínez-Alcantar 2021,2021,3 genes,Martínez-Alcant-2021-Participation of Acyl-Coe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19643,PHI:12088,UniProt,Q9HYU4,GenBank,AE004752_3,,,PAO1,fadD1,,fadD1Tn,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,long-chain-fatty-acid--CoA ligase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34867927,PubMed,10.3389/fmicb.2021.785112,Front Microbiol. 2021 Nov 16;12:785112,jesus.campos@umich.mx,"The fadD4 single mutant increased lethality compared to the PAO1 wild-type (WT) strain; however, the double mutants fadD1/fadD2, fadD1/fadD4, and fadD2/fadD4 and single mutant fadD2 increased worm survival.",L Martínez-Alcantar 2021,2021,3 genes,Martínez-Alcant-2021-Participation of Acyl-Coe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19644,PHI:12090,UniProt,A0A2C9WXX7,GenBank,OTI58916,,,S567_C10_BS,fadD4,,fadD4::Gm,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,long-chain-fatty-acid--CoA ligase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34867927,PubMed,10.3389/fmicb.2021.785112,Front Microbiol. 2021 Nov 16;12:785112,jesus.campos@umich.mx,"The fadD4 single mutant increased lethality compared to the PAO1 wild-type (WT) strain; however, the double mutants fadD1/fadD2, fadD1/fadD4, and fadD2/fadD4 and single mutant fadD2 increased worm survival.",L Martínez-Alcantar 2021,2021,3 genes,Martínez-Alcant-2021-Participation of Acyl-Coe,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19645,PHI:12091,,no data found,,,,,,pbtA,,,,,,PHI:12092,55601,Vibrio anguillarum,989499,RV22,vibriosis,bony fishes,28829,Solea senegalensis (related: Senegalese sole),,,,,AraC-like transcriptional activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34867865,PubMed,10.3389/fmicb.2021.748147,Front Microbiol. 2021 Nov 19;12:748147,miguel.balado@usc.es,"PbtA inactivation led to an inability to grow under iron restriction, a loss of the outer membrane piscibactin transporter FrpA, and a significant decrease in virulence for fish.",M A Lages 2021,2021,4 genes,Lages-2021-The Temperature-Dependent Expressio,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19646,PHI:12092,UniProt,Q0E7C4,GenBank,CAJ45639,,,RV22,vabF,,,,,,PHI:12091,55601,Vibrio anguillarum,989499,RV22,vibriosis,bony fishes,28829,Solea senegalensis (related: Senegalese sole),,,,,vanchrobactin synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34867865,PubMed,10.3389/fmicb.2021.748147,Front Microbiol. 2021 Nov 19;12:748147,miguel.balado@usc.es,"PbtA inactivation led to an inability to grow under iron restriction, a loss of the outer membrane piscibactin transporter FrpA, and a significant decrease in virulence for fish.",M A Lages 2021,2021,4 genes,Lages-2021-The Temperature-Dependent Expressio,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19647,PHI:12093,UniProt,S4VIT0,GenBank,AGO64128,,,M93Sm,hns,,,,,,PHI:12092,55601,Vibrio anguillarum,989499,RV22,vibriosis,bony fishes,28829,Solea senegalensis (related: Senegalese sole),,,,,DNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34867865,PubMed,10.3389/fmicb.2021.748147,Front Microbiol. 2021 Nov 19;12:748147,miguel.balado@usc.es,"PbtA inactivation led to an inability to grow under iron restriction, a loss of the outer membrane piscibactin transporter FrpA, and a significant decrease in virulence for fish.",M A Lages 2021,2021,4 genes,Lages-2021-The Temperature-Dependent Expressio,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19648,PHI:12092,UniProt,Q0E7C4,GenBank,CAJ45639,,,RV22,vabF,,,,,,PHI:12093,55601,Vibrio anguillarum,989499,RV22,vibriosis,bony fishes,28829,Solea senegalensis (related: Senegalese sole),,,,,vanchrobactin synthase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34867865,PubMed,10.3389/fmicb.2021.748147,Front Microbiol. 2021 Nov 19;12:748147,miguel.balado@usc.es,"PbtA inactivation led to an inability to grow under iron restriction, a loss of the outer membrane piscibactin transporter FrpA, and a significant decrease in virulence for fish.",M A Lages 2021,2021,4 genes,Lages-2021-The Temperature-Dependent Expressio,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19649,PHI:12094,,no data found,,,,,,irp1,,,,,,PHI:12092,55601,Vibrio anguillarum,989499,RV22,vibriosis,bony fishes,28829,Solea senegalensis (related: Senegalese sole),,,,,siderophore piscibactin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34867865,PubMed,10.3389/fmicb.2021.748147,Front Microbiol. 2021 Nov 19;12:748147,miguel.balado@usc.es,"PbtA inactivation led to an inability to grow under iron restriction, a loss of the outer membrane piscibactin transporter FrpA, and a significant decrease in virulence for fish.",M A Lages 2021,2021,4 genes,Lages-2021-The Temperature-Dependent Expressio,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19650,PHI:12095,UniProt,A0A1D8PIE8,GenBank,AOW27926,,,SC5314,rha1 (C2_09460C_A),chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,zinc cluster transcription factor,,,,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34849863,PubMed,10.1093/genetics/iyab155,Genetics. 2022 Jan 4;220(1):iyab155,malcolm.whiteway@concordia.ca,"The gain-of-function allele of RHA1, but not the deletion, impaired virulence significantly compared to the WT.",R Parvizi Omran 2022,2022,1 gene,Parvizi Omran-2022-The zinc cluster transcript,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19651,PHI:12095,UniProt,A0A1D8PIE8,GenBank,AOW27926,,,SC5314,rha1 (C2_09460C_A),chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,zinc cluster transcription factor,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34849863,PubMed,10.1093/genetics/iyab155,Genetics. 2022 Jan 4;220(1):iyab155,malcolm.whiteway@concordia.ca,"The gain-of-function allele of RHA1, but not the deletion, impaired virulence significantly compared to the WT.",R Parvizi Omran 2022,2022,1 gene,Parvizi Omran-2022-The zinc cluster transcript,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19652,PHI:12096,,no data found,GenBank,AKP26268,,,UP-MMC-NIID LP,PerRA (LIMLP_10155),chromosome 1,,,,,,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,liver; kidney,Fur family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,34855911,PubMed,10.1371/journal.ppat.1009087,PLoS Pathog. 2021 Dec 2;17(12):e1009087,nadia.benaroudj@pasteur.fr,"The concomitant inactivation of perRA and perRB resulted in a higher tolerance to both peroxide and superoxide and, unlike the single mutants, a double perRAperRB mutant was avirulent.",C Zavala-Alvarado 2021,2021,2 genes,Zavala-Alvarado-2021-The oxidative stress resp,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19653,PHI:12097,,no data found,GenBank,AKP25466,,,UP-MMC-NIID LP,PerRB (LIMLP_05620),chromosome 1,,,,,,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,liver; kidney,Fur family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,34855911,PubMed,10.1371/journal.ppat.1009087,PLoS Pathog. 2021 Dec 2;17(12):e1009087,nadia.benaroudj@pasteur.fr,"The concomitant inactivation of perRA and perRB resulted in a higher tolerance to both peroxide and superoxide and, unlike the single mutants, a double perRAperRB mutant was avirulent.",C Zavala-Alvarado 2021,2021,2 genes,Zavala-Alvarado-2021-The oxidative stress resp,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19654,PHI:12096,,no data found,GenBank,AKP26268,,,UP-MMC-NIID LP,PerRA (LIMLP_10155),chromosome 1,,,,,PHI:12097,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,liver; kidney,Fur family transcriptional regulator,,,,loss of pathogenicity,,,,,,,,wild type,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,34855911,PubMed,10.1371/journal.ppat.1009087,PLoS Pathog. 2021 Dec 2;17(12):e1009087,nadia.benaroudj@pasteur.fr,"The concomitant inactivation of perRA and perRB resulted in a higher tolerance to both peroxide and superoxide and, unlike the single mutants, a double perRAperRB mutant was avirulent.",C Zavala-Alvarado 2021,2021,2 genes,Zavala-Alvarado-2021-The oxidative stress resp,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19655,PHI:12097,,no data found,GenBank,AKP25466,,,UP-MMC-NIID LP,PerRB (LIMLP_05620),chromosome 1,,,,,PHI:12096,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,liver; kidney,Fur family transcriptional regulator,,,,loss of pathogenicity,,,,,,,,wild type,,no,H2O2; paraquat,H2O2: CHEBI:16240; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,YVS,34855911,PubMed,10.1371/journal.ppat.1009087,PLoS Pathog. 2021 Dec 2;17(12):e1009087,nadia.benaroudj@pasteur.fr,"The concomitant inactivation of perRA and perRB resulted in a higher tolerance to both peroxide and superoxide and, unlike the single mutants, a double perRAperRB mutant was avirulent.",C Zavala-Alvarado 2021,2021,2 genes,Zavala-Alvarado-2021-The oxidative stress resp,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19656,PHI:12098,,no data found,GenBank,AKP26268,,,UP-MMC-NIID LP,PerRA (LIMLP_10155),chromosome 1,,,,,,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,kidney,Fur family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34855918,PubMed,10.1371/journal.ppat.1009078,PLoS Pathog. 2021 Dec 2;17(12):e1009078,mcaima@uchc.edu,L. interrogans required at least one functional PerR for infectivity and renal colonization in a reservoir host.,A A Grassmann 2021,2021,4 genes,Grassmann-2021-The FUR-like regulators PerRA a,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19657,PHI:12099,,no data found,GenBank,AKP25466,,,UP-MMC-NIID LP,PerRB (LIMLP_05620),chromosome 1,,,,,,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,kidney,Fur family transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34855918,PubMed,10.1371/journal.ppat.1009078,PLoS Pathog. 2021 Dec 2;17(12):e1009078,mcaima@uchc.edu,L. interrogans required at least one functional PerR for infectivity and renal colonization in a reservoir host.,A A Grassmann 2021,2021,4 genes,Grassmann-2021-The FUR-like regulators PerRA a,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19658,PHI:12098,,no data found,GenBank,AKP26268,,,UP-MMC-NIID LP,PerRA (LIMLP_10155),chromosome 1,,,,,PHI:12099,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,kidney,Fur family transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34855918,PubMed,10.1371/journal.ppat.1009078,PLoS Pathog. 2021 Dec 2;17(12):e1009078,mcaima@uchc.edu,L. interrogans required at least one functional PerR for infectivity and renal colonization in a reservoir host.,A A Grassmann 2021,2021,4 genes,Grassmann-2021-The FUR-like regulators PerRA a,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19659,PHI:12099,,no data found,GenBank,AKP25466,,,UP-MMC-NIID LP,PerRB (LIMLP_05620),chromosome 1,,,,,PHI:12098,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,kidney,Fur family transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34855918,PubMed,10.1371/journal.ppat.1009078,PLoS Pathog. 2021 Dec 2;17(12):e1009078,mcaima@uchc.edu,L. interrogans required at least one functional PerR for infectivity and renal colonization in a reservoir host.,A A Grassmann 2021,2021,4 genes,Grassmann-2021-The FUR-like regulators PerRA a,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19660,PHI:12100,,no data found,,,,,,lvrA,,,,,,PHI:12101,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,kidney,sensory histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34855918,PubMed,10.1371/journal.ppat.1009078,PLoS Pathog. 2021 Dec 2;17(12):e1009078,mcaima@uchc.edu,Loss of LvrAB alone was not responsible for avirulence of the perRA/B double mutant in mice.,A A Grassmann 2021,2021,4 genes,Grassmann-2021-The FUR-like regulators PerRA a,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19661,PHI:12101,,no data found,,,,,,lvrB,,,,,,PHI:12100,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,kidney,sensory histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34855918,PubMed,10.1371/journal.ppat.1009078,PLoS Pathog. 2021 Dec 2;17(12):e1009078,mcaima@uchc.edu,Loss of LvrAB alone was not responsible for avirulence of the perRA/B double mutant in mice.,A A Grassmann 2021,2021,4 genes,Grassmann-2021-The FUR-like regulators PerRA a,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19662,PHI:12101,,no data found,,,,,,lvrB,,,,,,,173,Leptospira interrogans,,serovar Manilae strain L495,leptospirosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,kidney,sensory histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34855918,PubMed,10.1371/journal.ppat.1009078,PLoS Pathog. 2021 Dec 2;17(12):e1009078,mcaima@uchc.edu,Loss of LvrAB alone was not responsible for avirulence of the perRA/B double mutant in mice.,A A Grassmann 2021,2021,4 genes,Grassmann-2021-The FUR-like regulators PerRA a,BATCH_110B,2022-03-01,MC,,,,,,,,,,,,,
,,Record 19663,PHI:12102,UniProt,J9VQF6,GenBank,AFR96712,,,H99,Dnj4 (CNAG_03487),chromosome 8,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; lung,nuclear J domain protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,hydroxyurea; methyl methanesulfonate; 4-nitroquinoline-1-oxide,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; 4-nitroquinoline-1-oxide  CAS no.: CAS:56-57-5,,,,,gene mutation; gene complementation,,,YVS,34933457,PubMed,10.1128/mbio.03273-21,mBio. 2021 Dec 21;12(6):e0327321,kronstad@msl.ubc.ca,Dnj4 was found to be dispensable for disease in a mouse model of cryptococcosis.,L C Horianopoulos 2021,2021,1 gene,Horianopoulos-2021-A J Domain Protein Function,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19664,PHI:12103,UniProt,Q7NUT7,GenBank,AAQ60280,,,ATCC 12472,escU,,,,,,,536,Chromobacterium violaceum,,ATCC 31532,necrotic abscesses,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver,type III secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34946027,PubMed,10.3390/microorganisms9122424,Microorganisms. 2021 Nov 25;9(12):2424,alucard_d_n@hotmail.com,ΔEscU induced a smaller abscess area and necrosis whereas ΔcviI induced a larger necrotic area.,J L Díaz-Núñez 2021,2021,5 genes,Díaz-Núñez-2021-Anti-Virulence Properties of P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19665,PHI:12104,UniProt,Q7NQP6,GenBank,AAQ61751,,,ATCC 12472,cviI,,,,,,,536,Chromobacterium violaceum,,ATCC 31532,necrotic abscesses,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver,acyl-homoserine-lactone synthase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34946027,PubMed,10.3390/microorganisms9122425,Microorganisms. 2021 Nov 25;9(12):2424,alucard_d_n@hotmail.com,ΔEscU induced a smaller abscess area and necrosis whereas ΔcviI induced a larger necrotic area.,J L Díaz-Núñez 2021,2021,5 genes,Díaz-Núñez-2021-Anti-Virulence Properties of P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19666,PHI:12105,UniProt,A0A0H2Z901,GenBank,ABJ10611,,,UCBPP-PA14,lasR,,,,,,PHI:12106,287,Pseudomonas aeruginosa,652611,PA14,necrotic abscesses,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34946027,PubMed,10.3390/microorganisms9122426,Microorganisms. 2021 Nov 25;9(12):2424,alucard_d_n@hotmail.com,"Interruption of the QS (ΔlasR/ΔrhlR) and T3SS (ΔpscC) systems increased the survival of the mice to 100% and reduced the pathogenicity of the bacteria, with the effect being more evident with the ΔpscC strain, which was not able to establish and generate damage.",J L Díaz-Núñez 2021,2021,5 genes,Díaz-Núñez-2021-Anti-Virulence Properties of P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19667,PHI:12106,UniProt,A0A0H2ZEG8,GenBank,ABJ12732,,,UCBPP-PA14,rhlR,,,,,,PHI:12105,287,Pseudomonas aeruginosa,652611,PA14,necrotic abscesses,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver,acylhomoserine lactone dependent transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34946027,PubMed,10.3390/microorganisms9122427,Microorganisms. 2021 Nov 25;9(12):2424,alucard_d_n@hotmail.com,"Interruption of the QS (ΔlasR/ΔrhlR) and T3SS (ΔpscC) systems increased the survival of the mice to 100% and reduced the pathogenicity of the bacteria, with the effect being more evident with the ΔpscC strain, which was not able to establish and generate damage.",J L Díaz-Núñez 2021,2021,5 genes,Díaz-Núñez-2021-Anti-Virulence Properties of P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19668,PHI:12107,UniProt,A0A0H2Z8H0,GenBank,ABJ10902,,,UCBPP-PA14,pscC,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,necrotic abscesses,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver,type 3 secretion system secretin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,34946027,PubMed,10.3390/microorganisms9122428,Microorganisms. 2021 Nov 25;9(12):2424,alucard_d_n@hotmail.com,"Interruption of the QS (ΔlasR/ΔrhlR) and T3SS (ΔpscC) systems increased the survival of the mice to 100% and reduced the pathogenicity of the bacteria, with the effect being more evident with the ΔpscC strain, which was not able to establish and generate damage.",J L Díaz-Núñez 2022,2021,5 genes,Díaz-Núñez-2021-Anti-Virulence Properties of P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19669,PHI:12108,UniProt,E0W4Q8,GenBank,AEK80853,,,P7076,PsAvh181,,,,,,,67593,Phytophthora sojae,1094619,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Hefeng 47,,,hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,34843607,PubMed,10.1371/journal.ppat.1010104,PLoS Pathog. 2021 Nov 29;17(11):e1010104,wangyc@njau.edu.cn,PsAvh181 was essential for the full virulence of P. sojae.,H Wang 2021,2021,1 gene,Wang-2021-An atypical Phytophthora sojae RxLR,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19670,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: Pig),NPTr cell line,,,tracheal epithelium,prolipoprotein diacylglyceryltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Absence of the lipoprotein maturation enzymes did not affect S. suis serotype 2 adhesion to and invasion of respiratory epithelial cells.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19671,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: Pig),NPTr cell line,,,tracheal epithelium,lipoprotein signal peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Absence of the lipoprotein maturation enzymes did not affect S. suis serotype 2 adhesion to and invasion of respiratory epithelial cells.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19672,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,PHI:12110,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: Pig),NPTr cell line,,,tracheal epithelium,prolipoprotein diacylglyceryltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Absence of the lipoprotein maturation enzymes did not affect S. suis serotype 2 adhesion to and invasion of respiratory epithelial cells.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19673,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,PHI:12109,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: Pig),NPTr cell line,,,tracheal epithelium,lipoprotein signal peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Absence of the lipoprotein maturation enzymes did not affect S. suis serotype 2 adhesion to and invasion of respiratory epithelial cells.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19674,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: Pig),NPTr cell line,,,tracheal epithelium,prolipoprotein diacylglyceryltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Absence of the lipoprotein maturation enzymes did not affect S. suis serotype 2 adhesion to and invasion of respiratory epithelial cells.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19675,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: Pig),NPTr cell line,,,tracheal epithelium,lipoprotein signal peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Absence of the lipoprotein maturation enzymes did not affect S. suis serotype 2 adhesion to and invasion of respiratory epithelial cells.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19676,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,PHI:12110,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: Pig),NPTr cell line,,,tracheal epithelium,prolipoprotein diacylglyceryltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Absence of the lipoprotein maturation enzymes did not affect S. suis serotype 2 adhesion to and invasion of respiratory epithelial cells.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19677,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,PHI:12109,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,even-toed ungulates,9823,Sus scrofa (related: Pig),NPTr cell line,,,tracheal epithelium,lipoprotein signal peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Absence of the lipoprotein maturation enzymes did not affect S. suis serotype 2 adhesion to and invasion of respiratory epithelial cells.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19678,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,blood,prolipoprotein diacylglyceryltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"For the ST1 strain P1/7, no differences were observed between the acute blood bacterial burden of mice infected with the wild-type or mutants. Conversely, for the ST7 strain SC84, although no significant differences were observed with the Dlgt mutant, a slight decrease in blood bacterial burden was observed with the Δlsp mutant and Δlgt/Δlsp double mutant strain at 12 and 24 h.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19679,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,blood,lipoprotein signal peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"For the ST1 strain P1/7, no differences were observed between the acute blood bacterial burden of mice infected with the wild-type or mutants. Conversely, for the ST7 strain SC84, although no significant differences were observed with the Dlgt mutant, a slight decrease in blood bacterial burden was observed with the Δlsp mutant and Δlgt/Δlsp double mutant strain at 12 and 24 h.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19680,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,PHI:12110,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,blood,prolipoprotein diacylglyceryltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"For the ST1 strain P1/7, no differences were observed between the acute blood bacterial burden of mice infected with the wild-type or mutants. Conversely, for the ST7 strain SC84, although no significant differences were observed with the Dlgt mutant, a slight decrease in blood bacterial burden was observed with the Δlsp mutant and Δlgt/Δlsp double mutant strain at 12 and 24 h.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19681,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,PHI:12109,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,blood,lipoprotein signal peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"For the ST1 strain P1/7, no differences were observed between the acute blood bacterial burden of mice infected with the wild-type or mutants. Conversely, for the ST7 strain SC84, although no significant differences were observed with the Dlgt mutant, a slight decrease in blood bacterial burden was observed with the Δlsp mutant and Δlgt/Δlsp double mutant strain at 12 and 24 h.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19682,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,blood,prolipoprotein diacylglyceryltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"For the ST1 strain P1/7, no differences were observed between the acute blood bacterial burden of mice infected with the wild-type or mutants. Conversely, for the ST7 strain SC84, although no significant differences were observed with the Dlgt mutant, a slight decrease in blood bacterial burden was observed with the Δlsp mutant and Δlgt/Δlsp double mutant strain at 12 and 24 h.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19683,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,blood,lipoprotein signal peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"For the ST1 strain P1/7, no differences were observed between the acute blood bacterial burden of mice infected with the wild-type or mutants. Conversely, for the ST7 strain SC84, although no significant differences were observed with the Dlgt mutant, a slight decrease in blood bacterial burden was observed with the Δlsp mutant and Δlgt/Δlsp double mutant strain at 12 and 24 h.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19684,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,PHI:12110,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,blood,prolipoprotein diacylglyceryltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"For the ST1 strain P1/7, no differences were observed between the acute blood bacterial burden of mice infected with the wild-type or mutants. Conversely, for the ST7 strain SC84, although no significant differences were observed with the Dlgt mutant, a slight decrease in blood bacterial burden was observed with the Δlsp mutant and Δlgt/Δlsp double mutant strain at 12 and 24 h.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19685,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,PHI:12109,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,blood,lipoprotein signal peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"For the ST1 strain P1/7, no differences were observed between the acute blood bacterial burden of mice infected with the wild-type or mutants. Conversely, for the ST7 strain SC84, although no significant differences were observed with the Dlgt mutant, a slight decrease in blood bacterial burden was observed with the Δlsp mutant and Δlgt/Δlsp double mutant strain at 12 and 24 h.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19686,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,prolipoprotein diacylglyceryltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Only the Δlgt/Δlsp double mutant was significantly less virulent than the wild-type P2/7 ST1 strain.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19687,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,lipoprotein signal peptidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Only the Δlgt/Δlsp double mutant was significantly less virulent than the wild-type P2/7 ST1 strain.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19688,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,PHI:12110,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,prolipoprotein diacylglyceryltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Only the Δlgt/Δlsp double mutant was significantly less virulent than the wild-type P2/7 ST1 strain.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19689,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,PHI:12109,1307,Streptococcus suis,,P1/7,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,lipoprotein signal peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,Only the Δlgt/Δlsp double mutant was significantly less virulent than the wild-type P2/7 ST1 strain.,S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19690,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,prolipoprotein diacylglyceryltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"In the ST7 strain SC84, both single mutants as well as the Δlgt/Δlsp double mutant were signi?cantly less virulent.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19691,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,lipoprotein signal peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"In the ST7 strain SC84, both single mutants as well as the Δlgt/Δlsp double mutant were signi?cantly less virulent.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19692,PHI:12109,UniProt,A4VWT2,GenBank,ABP90571,,,05ZYH33,lgt,,,,,,PHI:12110,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,prolipoprotein diacylglyceryltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"In the ST7 strain SC84, both single mutants as well as the Δlgt/Δlsp double mutant were signi?cantly less virulent.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19693,PHI:12110,UniProt,Q7X4K0,GenBank,AAP49461,,,ivs-23,lsp,,,,,,PHI:12109,1307,Streptococcus suis,,SC84,meningitis; septicemia; streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,lipoprotein signal peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34835511,PubMed,10.3390/microorganisms9112386,Microorganisms. 2021 Nov 19;9(11):2386,marcelo.gottschalk@umontreal.ca,"In the ST7 strain SC84, both single mutants as well as the Δlgt/Δlsp double mutant were signi?cantly less virulent.",S Payen 2021,2021,2 genes,Payen-2021-Role of Maturation of Lipoproteins,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19694,PHI:12111,UniProt,Q0WXM3,GenBank,BAE98264,,,Mel02010,Fow2,,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici strain CK3-1,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ponderosa,,,seedling; root,Zn(II)2Cys6-type transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full,,,YVS,35154061,PubMed,10.3389/fmicb.2022.826677,Front Microbiol. 2022 Jan 27;13:826677,yuichiro.iida@setsunan.ac.jp,Pre-inoculation of melon or tomato roots with strain ΔFOW2 conidia markedly reduced disease incidence caused by the parental wildtype strain.,Y Iida 2022,2022,3 genes,Iida-2022-Biocontrol Activity of Nonpathogenic,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19695,PHI:12111,UniProt,Q0WXM3,GenBank,BAE98264,,,Mel02010,Fow2,,,,,,,5507,Fusarium oxysporum,,f. sp. melonis strain Mel020120,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ponderosa,,,seedling; root,Zn(II)2Cys6-type transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full,,,YVS,35154061,PubMed,10.3389/fmicb.2022.826677,Front Microbiol. 2022 Jan 27;13:826677,yuichiro.iida@setsunan.ac.jp,Pre-inoculation of melon or tomato roots with strain ΔFOW2 conidia markedly reduced disease incidence caused by the parental wildtype strain.,Y Iida 2022,2022,3 genes,Iida-2022-Biocontrol Activity of Nonpathogenic,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19696,PHI:12111,UniProt,Q0WXM3,GenBank,BAE98264,,,Mel02010,Fow2,,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici strain CK3-1,Fusarium wilt,eudicots,3656,Cucumis melo (related: muskmelon),cv. Amus,,,seedling; root,Zn(II)2Cys6-type transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full,,,YVS,35154061,PubMed,10.3389/fmicb.2022.826677,Front Microbiol. 2022 Jan 27;13:826677,yuichiro.iida@setsunan.ac.jp,Pre-inoculation of melon or tomato roots with strain ΔFOW2 conidia markedly reduced disease incidence caused by the parental wildtype strain.,Y Iida 2022,2022,3 genes,Iida-2022-Biocontrol Activity of Nonpathogenic,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19697,PHI:12111,UniProt,Q0WXM3,GenBank,BAE98264,,,Mel02010,Fow2,,,,,,,5507,Fusarium oxysporum,,f. sp. melonis strain Mel020120,Fusarium wilt,eudicots,3656,Cucumis melo (related: muskmelon),cv. Amus,,,seedling; root,Zn(II)2Cys6-type transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full,,,YVS,35154061,PubMed,10.3389/fmicb.2022.826677,Front Microbiol. 2022 Jan 27;13:826677,yuichiro.iida@setsunan.ac.jp,Pre-inoculation of melon or tomato roots with strain ΔFOW2 conidia markedly reduced disease incidence caused by the parental wildtype strain.,Y Iida 2022,2022,3 genes,Iida-2022-Biocontrol Activity of Nonpathogenic,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19698,PHI:12111,UniProt,Q0WXM3,GenBank,BAE98264,,,Mel02010,Fow2,,,,,,,5507,Fusarium oxysporum,,MFG6,Fusarium wilt,eudicots,3656,Cucumis melo (related: muskmelon),cv. Amus,,,seedling; root,Zn(II)2Cys6-type transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full,,,YVS,35154061,PubMed,10.3389/fmicb.2022.826677,Front Microbiol. 2022 Jan 27;13:826677,yuichiro.iida@setsunan.ac.jp,Pre-inoculation of melon or tomato roots with strain ΔFOW2 conidia markedly reduced disease incidence caused by the parental wildtype strain.,Y Iida 2022,2022,3 genes,Iida-2022-Biocontrol Activity of Nonpathogenic,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19699,PHI:12112,UniProt,Q9HGU2,GenBank,AF286533_1,,,,FMK1,,,,,,,5507,Fusarium oxysporum,,f. sp. melonis strain Mel020120,Fusarium wilt,eudicots,3656,Cucumis melo (related: muskmelon),cv. Amus,,,seedling; root,mitogen-activated protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35154061,PubMed,10.3389/fmicb.2022.826677,Front Microbiol. 2022 Jan 27;13:826677,yuichiro.iida@setsunan.ac.jp,Pre-inoculation of melon or tomato roots with strain ΔFOW2 conidia markedly reduced disease incidence caused by the parental wildtype strain.,Y Iida 2022,2022,3 genes,Iida-2022-Biocontrol Activity of Nonpathogenic,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19700,PHI:12113,UniProt,Q6B957,GenBank,AAT85969,,,,FRP1,,,,,,,5507,Fusarium oxysporum,,f. sp. melonis strain Mel020120,Fusarium wilt,eudicots,3656,Cucumis melo (related: muskmelon),cv. Amus,,,seedling; root,F-box protein required for pathogenicity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35154061,PubMed,10.3389/fmicb.2022.826677,Front Microbiol. 2022 Jan 27;13:826677,yuichiro.iida@setsunan.ac.jp,Pre-inoculation of melon or tomato roots with strain ΔFOW2 conidia markedly reduced disease incidence caused by the parental wildtype strain.,Y Iida 2022,2022,3 genes,Iida-2022-Biocontrol Activity of Nonpathogenic,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19701,PHI:12114,UniProt,O97209,GenBank,CAC22625,,,Friedlin,PES (LmjF.04.0810),,,,,,,5664,Leishmania major,860569,Lv39c5,leishmaniasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage; footpad,pescadillo homolog,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34830469,PubMed,10.3390/ijms222212592,Int J Mol Sci. 2021 Nov 22;22(22):12592,panguewa@unav.es,A dramatic increase in the ratio of cell infection within macrophages in mutant parasites overexpressing LmjPES was observed. BALB/c mice infected with these transgenic parasites exhibited higher footpad inflammation compared to those inoculated with non-overexpressing parasites.,M Algarabel 2021,2021,1 gene,"Algarabel-2021-In Leishmania major, the Homolo",BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19702,PHI:12115,UniProt,Q2YJ48,GenBank,,,,,BspJ (BAB_RS26920/BAB2_0119),,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,nucleomodulin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34841746,PubMed,10.4142/jvs.21224,J Vet Sci. 2022 Jan;23(1):e8,chuangfu_chen@163.com,"The knockout of BspJ altered the secretion of cytokines (interleukin [IL]-6, IL-1β, IL-10, tumor necrosis factor-α, interferon-γ) in host cells and in mice to affect the intracellular survival of Brucella.",Z Ma 2022,2022,1 gene,Ma-2022-Nucleomodulin BspJ as an effector prom,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19703,PHI:12115,UniProt,Q2YJ48,GenBank,,,,,BspJ (BAB_RS26920/BAB2_0119),,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,nucleomodulin,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34841746,PubMed,10.4142/jvs.21224,J Vet Sci. 2022 Jan;23(1):e8,chuangfu_chen@163.com,"The knockout of BspJ altered the secretion of cytokines (interleukin [IL]-6, IL-1β, IL-10, tumor necrosis factor-α, interferon-γ) in host cells and in mice to affect the intracellular survival of Brucella.",Z Ma 2022,2022,1 gene,Ma-2022-Nucleomodulin BspJ as an effector prom,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19704,PHI:12116,,no data found,GenBank,OWY44029,,,,Gcn5 (AALT_g5778),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone acetyltransferase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,H2O2; cumyl hydroperoxide; SDS; NaCl; KCl; CaCl2; CuSO4; Congo red; sorbitol; hydroxyurea; methyl methanesulfonate; camptothecin; chlorothalonil; mancozeb; boscalid,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:30911; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19705,PHI:12117,,no data found,GenBank,OWY42999,,,,Sas3 (AALT_g515),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone acetyltransferase,,,,loss of pathogenicity,,,,,,reduced,,reduced,,no,H2O2; cumyl hydroperoxide; SDS; NaCl; KCl; CaCl2; CuSO4; Congo red; sorbitol; hydroxyurea; methyl methanesulfonate; camptothecin; chlorothalonil; mancozeb; boscalid,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:30911; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19706,PHI:12118,,no data found,GenBank,OWY41430,,,,Nat3 (AALT_g1183),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone acetyltransferase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19707,PHI:12119,,no data found,GenBank,OWY45989,,,,RTT109 (AALT_g1972),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone acetyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2; cumyl hydroperoxide; SDS; NaCl; KCl; CaCl2; CuSO4; Congo red; sorbitol; hydroxyurea; methyl methanesulfonate; camptothecin; chlorothalonil; mancozeb; boscalid,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:30911; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19708,PHI:12120,,no data found,GenBank,OWY48002,,,,Elp3 (AALT_g7656),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone acetyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2; cumyl hydroperoxide; SDS; NaCl; KCl; CaCl2; CuSO4; Congo red; sorbitol; hydroxyurea; methyl methanesulfonate; camptothecin; chlorothalonil; mancozeb; boscalid,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:30911; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19709,PHI:12121,,no data found,GenBank,OWY47068,,,,Sas2 (AALT_g11012),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone acetyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,H2O2; cumyl hydroperoxide; SDS; NaCl; KCl; CaCl2; CuSO4; Congo red; sorbitol; hydroxyurea; methyl methanesulfonate; camptothecin; chlorothalonil; mancozeb; boscalid,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:30911; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19710,PHI:12122,,no data found,GenBank,OWY58433,,,,Rpd3 (AALT_g9756),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone deacetylase,,,,reduced virulence,,,,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19711,PHI:12123,,no data found,GenBank,OAG21128,,,,Hos2 (AALT_g8381),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone deacetylase,,,,reduced virulence,,,,,,reduced,,reduced,,no,H2O2; cumyl hydroperoxide; SDS; NaCl; KCl; CaCl2; CuSO4; Congo red; sorbitol; hydroxyurea; methyl methanesulfonate; camptothecin; chlorothalonil; mancozeb; boscalid,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:30911; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19712,PHI:12124,,no data found,GenBank,OWY41865,,,,Hos3 (AALT_g1618),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone deacetylase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,H2O2; cumyl hydroperoxide; SDS; NaCl; KCl; CaCl2; CuSO4; Congo red; sorbitol; hydroxyurea; methyl methanesulfonate; camptothecin; chlorothalonil; mancozeb; boscalid,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:30911; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19713,PHI:12125,,no data found,GenBank,OWY48453,,,,Sir2 (AALT_g7248),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone deacetylase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,H2O2; cumyl hydroperoxide; SDS; NaCl; KCl; CaCl2; CuSO4; Congo red; sorbitol; hydroxyurea; methyl methanesulfonate; camptothecin; chlorothalonil; mancozeb; boscalid,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:30911; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19714,PHI:12126,,no data found,GenBank,OAG21128,,,,Hda1 (AALT_g4414),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone deacetylase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,H2O2; cumyl hydroperoxide; SDS; NaCl; KCl; CaCl2; CuSO4; Congo red; sorbitol; hydroxyurea; methyl methanesulfonate; camptothecin; chlorothalonil; mancozeb; boscalid,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:30911; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19715,PHI:12127,,no data found,GenBank,OWY49563,,,,Hst2 (AALT_g8522),,,,,,,5599,Alternaria alternata,,Z7,brown spot (Citrus),eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone deacetylase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,H2O2; cumyl hydroperoxide; SDS; NaCl; KCl; CaCl2; CuSO4; Congo red; sorbitol; hydroxyurea; methyl methanesulfonate; camptothecin; chlorothalonil; mancozeb; boscalid,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; SDS: CHEBI:8984; NaCl: CHEBI:26710; KCl: CHEBI:32588; CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; Congo red (CR): CHEBI:34653; sorbitol: CHEBI:30911; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full; gene complementation,,,YVS,34880849,PubMed,10.3389/fmicb.2021.783633,Front Microbiol. 2021 Nov 22;12:783633,fgmitter@ufl.edu,"ΔRTT109, ΔGcn5, and ΔHos2 showed severe defects in resistance to DNA-damaging agents, indicating the critical role of HATs and HDACs in DNA damage repair.",H Ma 2021,2021,12 genes,Ma-2021-Histone Acetyltransferases and Deacety,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19716,PHI:12128,UniProt,C5A956,GenBank,ACR29421,,,BGR1,bglu_1g23320,chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,stem; panicle,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35009038,PubMed,10.3390/plants11010034,Plants (Basel). 2021 Dec 23;11(1):34,titanic622@pusan.ac.kr,The deletion of the DUF2169 domain in bglu_1g23320 caused almost no difference in pathogenicity from wild-type BGR1.,N Kim 2021,2021,4 genes,"Kim-2021-T6SS Accessory Proteins, Including DU",BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19717,PHI:12129,UniProt,C5AMW0,GenBank,ACR31161,,,BGR1,bglu_2g07420,chromosome 2,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,stem; panicle,pentapeptide repeat-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35009038,PubMed,10.3390/plants11010034,Plants (Basel). 2021 Dec 23;11(1):34,titanic622@pusan.ac.kr,DUF2169 domain-containing protein and pentapeptide repeats region of bglu_2g07420 and bglu_2g07410 were involved in bacterial virulence to the rice plants.,N Kim 2021,2021,4 genes,"Kim-2021-T6SS Accessory Proteins, Including DU",BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19718,PHI:12130,UniProt,C5AMV9,GenBank,ACR31160,,,BGR1,bglu_2g07410,chromosome 2,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,stem; panicle,pentapeptide repeat-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35009038,PubMed,10.3390/plants11010034,Plants (Basel). 2021 Dec 23;11(1):34,titanic622@pusan.ac.kr,DUF2169 domain-containing protein and pentapeptide repeats region of bglu_2g07420 and bglu_2g07410 were involved in bacterial virulence to the rice plants.,N Kim 2021,2021,4 genes,"Kim-2021-T6SS Accessory Proteins, Including DU",BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19719,PHI:12129,UniProt,C5AMW0,GenBank,ACR31161,,,BGR1,bglu_2g07420,chromosome 2,"u2g07420PPR mutant, in which the C-terminal pentapeptide repeats region is deleted",,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,stem; panicle,pentapeptide repeat-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,35009038,PubMed,10.3390/plants11010034,Plants (Basel). 2021 Dec 23;11(1):34,titanic622@pusan.ac.kr,DUF2169 domain-containing protein and pentapeptide repeats region of bglu_2g07420 and bglu_2g07410 were involved in bacterial virulence to the rice plants.,N Kim 2021,2021,4 genes,"Kim-2021-T6SS Accessory Proteins, Including DU",BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19720,PHI:12129,UniProt,C5AMW0,GenBank,ACR31161,,,BGR1,bglu_2g07420,chromosome 2,,,,,PHI:12130,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,stem; panicle,pentapeptide repeat-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35009038,PubMed,10.3390/plants11010034,Plants (Basel). 2021 Dec 23;11(1):34,titanic622@pusan.ac.kr,DUF2169 domain-containing protein and pentapeptide repeats region of bglu_2g07420 and bglu_2g07410 were involved in bacterial virulence to the rice plants.,N Kim 2021,2021,4 genes,"Kim-2021-T6SS Accessory Proteins, Including DU",BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19721,PHI:12130,UniProt,C5AMV9,GenBank,ACR31160,,,BGR1,bglu_2g07410,chromosome 2,,,,,PHI:12129,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,stem; panicle,pentapeptide repeat-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35009038,PubMed,10.3390/plants11010034,Plants (Basel). 2021 Dec 23;11(1):34,titanic622@pusan.ac.kr,DUF2169 domain-containing protein and pentapeptide repeats region of bglu_2g07420 and bglu_2g07410 were involved in bacterial virulence to the rice plants.,N Kim 2021,2021,4 genes,"Kim-2021-T6SS Accessory Proteins, Including DU",BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19722,PHI:12131,UniProt,A0A2J9HJ00,GenBank,WP_012733555,,,,u2g07420 DUF2169,,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Saeilmi,,,stem; panicle,DUF2169 domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35009038,PubMed,10.3390/plants11010034,Plants (Basel). 2021 Dec 23;11(1):34,titanic622@pusan.ac.kr,"Only the DUF2169 domain (WP_012733555.1), which was encoded by bglu_2g07420 in the gene cluster of T6SS group_5, was involved in bacterial virulence to rice plants.",N Kim 2021,2021,4 genes,"Kim-2021-T6SS Accessory Proteins, Including DU",BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19723,PHI:12132,UniProt,Q8IEK1,GenBank,CAD52253,,,3D7,PfA-M1,chromosome 13,PfA-M1 without the signal peptide,,,,,5833,Plasmodium falciparum,36329,3D7,malaria,primates,9606,Homo sapiens (related: human),,,,erythrocyte,M1 alanyl-aminopeptidase,,,,reduced virulence,,,,,,,,reduced,,no,"calmidazolium; thapsigargin; monensin; E64d; bestatin; alanyl-7-amido-4-methylcoumarin; met-AMC, Leu-AMC, Arg-AMC",calmidazolium: CHEBI:75400; thapsigargin: CHEBI:9516; monensin: CHEBI:27617; E64d: CHEBI:101381; bestatin: CHEBI:3070; alanyl-7-amido-4-methylcoumarin CAS no.: CAS:77471-41-1; met-AMC CAS no.: CAS:94367-35-8; Leu-AMC CAS no.: CAS:66447-31-2; Arg-AMC: CAS:70274-89-4,,,,,altered gene expression / gene regulation: overexpression,,,YVS,34832608,PubMed,10.3390/pathogens10111452,Pathogens. 2021 Nov 10;10(11):1452,caldascarol22@gmail.com,"OverPfAM1 parasites presented a decrease in vitro growth, showing a reduced number of merozoites per schizont, and also a decrease in the iRBC area occupied by the parasite in trophozoite and schizontforms when compared to the controls.",C C Hoff 2021,2021,1 gene,Hoff-2021-Overexpression of Plasmodium falcipa,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19724,PHI:12133,UniProt,Q71QT8,GenBank,AF384808_1,,,wm777,Hsp90,,"conditional expression strain in which HSP90 was under control of the copper repressible promoter CTR4-2, was obtained by replacing 111 base pairs upstream of the first intron preceding the HSP90 start codon with a nourseothricin-resistance (NAT) cassette and the CTR4-2promoter",,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung,heat shock protein,,,,reduced virulence,,,,,,,,reduced,,no,fluconazole; radicicol; HSP 990; amphotericin B; NaCl; sorbitol; dithiothreitol; tunicamycin; SDS; calcofluor white; H2O2; MG132; benomyl; hydroxyurea; methyl methanesulfonate,"fluconazole   CHEBI   ID 46081,  radicicol: CHEBI:556075, 990; HSP  CAS no.: CAS:934343-74-5; amphotericin B: CHEBI:2682; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; dithiothreitol: CHEBI:42170; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; MG132: CHEBI:75142; benomyl: CHEBI:3015; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255",,,,,promoter mutation; other evidence: conditional expression,,,YVS,34849848,PubMed,10.1093/genetics/iyab164,Genetics. 2022 Jan 4;220(1):iyab164,leah.cowen@utoronto.ca,"Addition of copper to culture medium depleted Hsp90 transcript and protein levels in this strain, resulting in compromised fungal growth at host temperature; increased sensitivity to stressors, including the azole class of antifungals; altered C. neoformans morphology; and impaired melanin production.",C Fu 2022,2022,1 gene,Fu-2022-Genetic analysis of Hsp90 function in,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19725,PHI:12133,UniProt,Q71QT8,GenBank,AF384808_1,,,wm777,Hsp90,,"conditional expression strain in which HSP90 was under control of the copper repressible promoter CTR4-2, was obtained by replacing 111 base pairs upstream of the first intron preceding the HSP90 start codon with a nourseothricin-resistance (NAT) cassette and the CTR4-2promoter",,,,,5207,Cryptococcus neoformans,,KN99α,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),A/J,,,brain,heat shock protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,fluconazole; radicicol; HSP 990; amphotericin B; NaCl; sorbitol; dithiothreitol; tunicamycin; SDS; calcofluor white; H2O2; MG132; benomyl; hydroxyurea; methyl methanesulfonate,"fluconazole   CHEBI   ID 46081,  radicicol: CHEBI:556075, 990; HSP  CAS no.: CAS:934343-74-5; amphotericin B: CHEBI:2682; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; dithiothreitol: CHEBI:42170; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; MG132: CHEBI:75142; benomyl: CHEBI:3015; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255",,,,,promoter mutation; other evidence: conditional expression,,,YVS,34849848,PubMed,10.1093/genetics/iyab164,Genetics. 2022 Jan 4;220(1):iyab164,leah.cowen@utoronto.ca,"Addition of copper to culture medium depleted Hsp90 transcript and protein levels in this strain, resulting in compromised fungal growth at host temperature; increased sensitivity to stressors, including the azole class of antifungals; altered C. neoformans morphology; and impaired melanin production.",C Fu 2022,2022,1 gene,Fu-2022-Genetic analysis of Hsp90 function in,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19726,PHI:12134,UniProt,A0A3P0XXT6,GenBank,RRA57279,,,JF4680,essC,,,,,,,1311,Streptococcus agalactiae,342617,CJB111,meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; heart; brain,type VII secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34871327,PubMed,10.1371/journal.ppat.1010121,PLoS Pathog. 2021 Dec 6;17(12):e1010121,kelly.doran@cuanschutz.edu,T7SS contributed to virulence and meningitis development.,B L Spencer 2021,2021,3 genes,Spencer-2021-A type VII secretion system in Gr,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19727,PHI:12134,UniProt,A0A3P0XXT6,GenBank,RRA57279,,,JF4680,essC,,,,,,,1311,Streptococcus agalactiae,342617,CJB111,meningitis,primates,9606,Homo sapiens (related: human),,,,HCMEC cell,type VII secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34871327,PubMed,10.1371/journal.ppat.1010121,PLoS Pathog. 2021 Dec 6;17(12):e1010121,kelly.doran@cuanschutz.edu,T7SS contributed to virulence and meningitis development.,B L Spencer 2021,2021,3 genes,Spencer-2021-A type VII secretion system in Gr,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19728,PHI:12135,UniProt,A0A023SIL4,GenBank,AIK70845,,,GBS1-NY,esxA1,,,,,,PHI:12136,1311,Streptococcus agalactiae,342617,CJB111,meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; heart; brain,pore-forming protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34871327,PubMed,10.1371/journal.ppat.1010121,PLoS Pathog. 2021 Dec 6;17(12):e1010121,kelly.doran@cuanschutz.edu,T7SS contributed to virulence and meningitis development.,B L Spencer 2021,2021,3 genes,Spencer-2021-A type VII secretion system in Gr,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19729,PHI:12136,UniProt,A0A076Z9F7,GenBank,AIK71589,,,GBS1-NY,esxA2,,,,,,PHI:12135,1311,Streptococcus agalactiae,342617,CJB111,meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood; heart; brain,type VII secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34871327,PubMed,10.1371/journal.ppat.1010121,PLoS Pathog. 2021 Dec 6;17(12):e1010121,kelly.doran@cuanschutz.edu,T7SS contributed to virulence and meningitis development.,B L Spencer 2021,2021,3 genes,Spencer-2021-A type VII secretion system in Gr,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19730,PHI:12135,UniProt,A0A023SIL4,GenBank,AIK70845,,,GBS1-NY,esxA1,,,,,,PHI:12136,1311,Streptococcus agalactiae,342617,CJB111,meningitis,primates,9606,Homo sapiens (related: human),,,,HCMEC cell,pore-forming protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34871327,PubMed,10.1371/journal.ppat.1010121,PLoS Pathog. 2021 Dec 6;17(12):e1010121,kelly.doran@cuanschutz.edu,T7SS contributed to virulence and meningitis development.,B L Spencer 2021,2021,3 genes,Spencer-2021-A type VII secretion system in Gr,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19731,PHI:12136,UniProt,A0A076Z9F7,GenBank,AIK71589,,,GBS1-NY,esxA2,,,,,,PHI:12135,1311,Streptococcus agalactiae,342617,CJB111,meningitis,primates,9606,Homo sapiens (related: human),,,,HCMEC cell,type VII secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,YVS,34871327,PubMed,10.1371/journal.ppat.1010121,PLoS Pathog. 2021 Dec 6;17(12):e1010121,kelly.doran@cuanschutz.edu,T7SS contributed to virulence and meningitis development.,B L Spencer 2021,2021,3 genes,Spencer-2021-A type VII secretion system in Gr,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19732,PHI:12137,UniProt,I1RMR5,GenBank,CEF87892,,,PH-1,FgBem1 (FGSG_05261),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,defective,reduced,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19733,PHI:12138,UniProt,I1S0G1,GenBank,CEF75548,,,PH-1,FgSNX19 (FGSG_10187),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,wild type,reduced,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19734,PHI:12139,UniProt,A0A1C3YLQ0,GenBank,SCB65480,,,PH-1,FgMDM1 (FGSG_13543),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,wild type,increased,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19735,PHI:12140,UniProt,I1RZR4,GenBank,XP_011318823,,,PH-1,FgSPO14 (FGSG_09917),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19736,PHI:12141,UniProt,I1S8F9,GenBank,CEF85596,,,PH-1,FgYPR097 (FGSG_13137),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced,wild type,reduced,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19737,PHI:12142,UniProt,I1RFU6,GenBank,CEF74908,,,PH-1,FgYKR078 (FGSG_02586),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,increased virulence (hypervirulence),,,,,,reduced,wild type,increased,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19738,PHI:12143,UniProt,Q4I1H6,GenBank,ESU14338,,,PH-1,FgSNX3 (FGSG_08932),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,wild type,reduced,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19739,PHI:12144,UniProt,I1S5R2,GenBank,CEF75061,,,PH-1,FgMVP1 (FGSG_12183),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,wild type,increased,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19740,PHI:12145,UniProt,A0A098DW43,GenBank,CEF85577,,,PH-1,FgYPT35 (FGSG_17200),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced; aberrant,wild type,increased,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19741,PHI:12137,UniProt,I1RMR5,GenBank,CEF87892,,,PH-1,FgBem1 (FGSG_05261),chromosome 3,SH3-1 truncated,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene mutation,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19742,PHI:12137,UniProt,I1RMR5,GenBank,CEF87892,,,PH-1,FgBem1 (FGSG_05261),chromosome 3,SH3-2 truncated,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene mutation,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19743,PHI:12137,UniProt,I1RMR5,GenBank,CEF87892,,,PH-1,FgBem1 (FGSG_05261),chromosome 3,PX truncated,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced,aberrant,reduced,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene mutation,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19744,PHI:12137,UniProt,I1RMR5,GenBank,CEF87892,,,PH-1,FgBem1 (FGSG_05261),chromosome 3,PB1 truncated,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,inflorescence; coleoptile,PX domain-containing protein,,,,reduced virulence,,,,,,reduced,aberrant,reduced,,no,KCl; NaCl; D-sorbitol; H2O2; SDS; calcofluor white; Congo red,KCl: CHEBI:32588; NaCl: CHEBI:26710; D-sorbitol: CHEBI:30911; H2O2: CHEBI:16240; SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,gene mutation,,,YVS,34933449,PubMed,10.1128/mBio.02324-21,mBio. 2021 Dec 21;12(6):e0232421,wangzh@fafu.edu.cn,"The SH3, PX, and PB1 domains of FgBem1 were required for sexual development and virulence in F.graminearum.",Y Lou 2021,2021,9 genes,Lou-2021-Genome-Wide Characterization of PX Do,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19745,PHI:12146,UniProt,Q8ZLZ9,GenBank,AAL22052,,,LT2,qseC,,,,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,two-component regulatory system protein,,,,unaffected pathogenicity,,,,,,,,wild type; reduced,,no,L(-)-norepinephrine-(+)-bitartrate salt; dopamine hydrochloride; epinephrine hydrochloride; glucose; glycerol; ammonium sulphate; NaCl,L(-)-norepinephrine-(+)-bitartrate salt CAS no.: CAS:108341-18-0; dopamine hydrochloride: CHEBI:4698; epinephrine hydrochloride CAS no.: CAS:329-63-5; glucose: CHEBI:17234; glycerol: CHEBI:17754; ammonium sulphate: CHEBI:62946; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35137015,PubMed,10.1093/femsle/fnac012,FEMS Microbiol Lett. 2022 Feb 8:fnac012,ppef1@leicester.ac.uk,"Motility, biofilm formation and analysis of virulence of the mutants using two infection models were similar to the wild-type strains.",A Hamed 2022,2022,4 genes,Hamed-2022-Characterisation of the E. coli and,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19746,PHI:12147,UniProt,Q8X524,GenBank,AE005532_4,,,EDL933,qseC,,,,,,,562,Escherichia coli,,serotype O157:H7 strain 85-170,infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,two-component regulatory system protein,,,,unaffected pathogenicity,,,,,,,,wild type; reduced,,no,L(-)-norepinephrine-(+)-bitartrate salt; dopamine hydrochloride; epinephrine hydrochloride; glucose; glycerol; ammonium sulphate; NaCl,L(-)-norepinephrine-(+)-bitartrate salt CAS no.: CAS:108341-18-0; dopamine hydrochloride: CHEBI:4698; epinephrine hydrochloride CAS no.: CAS:329-63-5; glucose: CHEBI:17234; glycerol: CHEBI:17754; ammonium sulphate: CHEBI:62946; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35137015,PubMed,10.1093/femsle/fnac012,FEMS Microbiol Lett. 2022 Feb 8:fnac012,ppef1@leicester.ac.uk,"Motility, biofilm formation and analysis of virulence of the mutants using two infection models were similar to the wild-type strains.",A Hamed 2022,2022,4 genes,Hamed-2022-Characterisation of the E. coli and,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19747,PHI:12148,UniProt,A0A5Z5IUY8,GenBank,EBV8836849,,,CVM-N23826,qseE,,,,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,two-component regulatory system protein,,,,unaffected pathogenicity,,,,,,,,wild type; reduced,,no,L(-)-norepinephrine-(+)-bitartrate salt; dopamine hydrochloride; epinephrine hydrochloride; glucose; glycerol; ammonium sulphate; NaCl,L(-)-norepinephrine-(+)-bitartrate salt CAS no.: CAS:108341-18-0; dopamine hydrochloride: CHEBI:4698; epinephrine hydrochloride CAS no.: CAS:329-63-5; glucose: CHEBI:17234; glycerol: CHEBI:17754; ammonium sulphate: CHEBI:62946; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35137015,PubMed,10.1093/femsle/fnac012,FEMS Microbiol Lett. 2022 Feb 8:fnac012,ppef1@leicester.ac.uk,"Motility, biofilm formation and analysis of virulence of the mutants using two infection models were similar to the wild-type strains.",A Hamed 2022,2022,4 genes,Hamed-2022-Characterisation of the E. coli and,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19748,PHI:12149,UniProt,Q8XA47,GenBank,AE005486_1,,,EDL933,qseE,,,,,,,562,Escherichia coli,,serotype O157:H7 strain 85-170,infection,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,two-component regulatory system protein,,,,unaffected pathogenicity,,,,,,,,wild type; reduced,,no,L(-)-norepinephrine-(+)-bitartrate salt; dopamine hydrochloride; epinephrine hydrochloride; glucose; glycerol; ammonium sulphate; NaCl,L(-)-norepinephrine-(+)-bitartrate salt CAS no.: CAS:108341-18-0; dopamine hydrochloride: CHEBI:4698; epinephrine hydrochloride CAS no.: CAS:329-63-5; glucose: CHEBI:17234; glycerol: CHEBI:17754; ammonium sulphate: CHEBI:62946; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35137015,PubMed,10.1093/femsle/fnac012,FEMS Microbiol Lett. 2022 Feb 8:fnac012,ppef1@leicester.ac.uk,"Motility, biofilm formation and analysis of virulence of the mutants using two infection models were similar to the wild-type strains.",A Hamed 2022,2022,4 genes,Hamed-2022-Characterisation of the E. coli and,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19749,PHI:12146,UniProt,Q8ZLZ9,GenBank,AAL22052,,,LT2,qseC,,,,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,two-component regulatory system protein,,,,unaffected pathogenicity,,,,,,,,wild type; reduced,,no,L(-)-norepinephrine-(+)-bitartrate salt; dopamine hydrochloride; epinephrine hydrochloride; glucose; glycerol; ammonium sulphate; NaCl,L(-)-norepinephrine-(+)-bitartrate salt CAS no.: CAS:108341-18-0; dopamine hydrochloride: CHEBI:4698; epinephrine hydrochloride CAS no.: CAS:329-63-5; glucose: CHEBI:17234; glycerol: CHEBI:17754; ammonium sulphate: CHEBI:62946; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35137015,PubMed,10.1093/femsle/fnac012,FEMS Microbiol Lett. 2022 Feb 8:fnac012,ppef1@leicester.ac.uk,"Motility, biofilm formation and analysis of virulence of the mutants using two infection models were similar to the wild-type strains.",A Hamed 2022,2022,4 genes,Hamed-2022-Characterisation of the E. coli and,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19750,PHI:12147,UniProt,Q8X524,GenBank,AE005532_4,,,EDL933,qseC,,,,,,,562,Escherichia coli,,serotype O157:H7 strain 85-170,infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,two-component regulatory system protein,,,,reduced virulence,,,,,,,,wild type; reduced,,no,L(-)-norepinephrine-(+)-bitartrate salt; dopamine hydrochloride; epinephrine hydrochloride; glucose; glycerol; ammonium sulphate; NaCl,L(-)-norepinephrine-(+)-bitartrate salt CAS no.: CAS:108341-18-0; dopamine hydrochloride: CHEBI:4698; epinephrine hydrochloride CAS no.: CAS:329-63-5; glucose: CHEBI:17234; glycerol: CHEBI:17754; ammonium sulphate: CHEBI:62946; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35137015,PubMed,10.1093/femsle/fnac012,FEMS Microbiol Lett. 2022 Feb 8:fnac012,ppef1@leicester.ac.uk,"Motility, biofilm formation and analysis of virulence of the mutants using two infection models were similar to the wild-type strains.",A Hamed 2022,2022,4 genes,Hamed-2022-Characterisation of the E. coli and,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19751,PHI:12148,UniProt,A0A5Z5IUY8,GenBank,EBV8836849,,,CVM-N23826,qseE,,,,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,two-component regulatory system protein,,,,unaffected pathogenicity,,,,,,,,wild type; reduced,,no,L(-)-norepinephrine-(+)-bitartrate salt; dopamine hydrochloride; epinephrine hydrochloride; glucose; glycerol; ammonium sulphate; NaCl,L(-)-norepinephrine-(+)-bitartrate salt CAS no.: CAS:108341-18-0; dopamine hydrochloride: CHEBI:4698; epinephrine hydrochloride CAS no.: CAS:329-63-5; glucose: CHEBI:17234; glycerol: CHEBI:17754; ammonium sulphate: CHEBI:62946; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35137015,PubMed,10.1093/femsle/fnac012,FEMS Microbiol Lett. 2022 Feb 8:fnac012,ppef1@leicester.ac.uk,"Motility, biofilm formation and analysis of virulence of the mutants using two infection models were similar to the wild-type strains.",A Hamed 2022,2022,4 genes,Hamed-2022-Characterisation of the E. coli and,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19752,PHI:12149,UniProt,Q8XA47,GenBank,AE005486_1,,,EDL933,qseE,,,,,,,562,Escherichia coli,,serotype O157:H7 strain 85-170,infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,two-component regulatory system protein,,,,reduced virulence,,,,,,,,wild type; reduced,,no,L(-)-norepinephrine-(+)-bitartrate salt; dopamine hydrochloride; epinephrine hydrochloride; glucose; glycerol; ammonium sulphate; NaCl,L(-)-norepinephrine-(+)-bitartrate salt CAS no.: CAS:108341-18-0; dopamine hydrochloride: CHEBI:4698; epinephrine hydrochloride CAS no.: CAS:329-63-5; glucose: CHEBI:17234; glycerol: CHEBI:17754; ammonium sulphate: CHEBI:62946; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35137015,PubMed,10.1093/femsle/fnac012,FEMS Microbiol Lett. 2022 Feb 8:fnac012,ppef1@leicester.ac.uk,"Motility, biofilm formation and analysis of virulence of the mutants using two infection models were similar to the wild-type strains.",A Hamed 2022,2022,4 genes,Hamed-2022-Characterisation of the E. coli and,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19753,PHI:12146,UniProt,Q8ZLZ9,GenBank,AAL22052,,,LT2,qseC,,,,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,infection,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,two-component regulatory system protein,,,,unaffected pathogenicity,,,,,,,,wild type; reduced,,no,L(-)-norepinephrine-(+)-bitartrate salt; dopamine hydrochloride; epinephrine hydrochloride; glucose; glycerol; ammonium sulphate; NaCl,L(-)-norepinephrine-(+)-bitartrate salt CAS no.: CAS:108341-18-0; dopamine hydrochloride: CHEBI:4698; epinephrine hydrochloride CAS no.: CAS:329-63-5; glucose: CHEBI:17234; glycerol: CHEBI:17754; ammonium sulphate: CHEBI:62946; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35137015,PubMed,10.1093/femsle/fnac012,FEMS Microbiol Lett. 2022 Feb 8:fnac012,ppef1@leicester.ac.uk,"Motility, biofilm formation and analysis of virulence of the mutants using two infection models were similar to the wild-type strains.",A Hamed 2022,2022,4 genes,Hamed-2022-Characterisation of the E. coli and,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19754,PHI:12148,UniProt,A0A5Z5IUY8,GenBank,EBV8836849,,,CVM-N23826,qseE,,,,,,,28901,Salmonella enterica,909946,subsp. enterica serovar Typhimurium strain ST4/74,infection,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,two-component regulatory system protein,,,,unaffected pathogenicity,,,,,,,,wild type; reduced,,no,L(-)-norepinephrine-(+)-bitartrate salt; dopamine hydrochloride; epinephrine hydrochloride; glucose; glycerol; ammonium sulphate; NaCl,L(-)-norepinephrine-(+)-bitartrate salt CAS no.: CAS:108341-18-0; dopamine hydrochloride: CHEBI:4698; epinephrine hydrochloride CAS no.: CAS:329-63-5; glucose: CHEBI:17234; glycerol: CHEBI:17754; ammonium sulphate: CHEBI:62946; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35137015,PubMed,10.1093/femsle/fnac012,FEMS Microbiol Lett. 2022 Feb 8:fnac012,ppef1@leicester.ac.uk,"Motility, biofilm formation and analysis of virulence of the mutants using two infection models were similar to the wild-type strains.",A Hamed 2022,2022,4 genes,Hamed-2022-Characterisation of the E. coli and,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19755,PHI:12150,UniProt,A0A125YNY7,GenBank,EPR59118,,,GT1,SLP (Shewanella-like phosphatases) (TGGT1_254770),,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,ser/Thr phosphatase family protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19756,PHI:12151,UniProt,S7V0E9,GenBank,EPR63297,,,GT1,PP7 (TGGT1_251850),,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,protein-serine/threonine phosphatase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19757,PHI:12152,UniProt,S7UTT9,GenBank,EPR61052,,,GT1,PP5 (TGGT1_312200),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,protein-serine/threonine phosphatase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19758,PHI:12151,UniProt,S7V0E9,GenBank,EPR63297,,,GT1,PP7 (TGGT1_251850),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,protein-serine/threonine phosphatase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19759,PHI:12153,UniProt,S7WL31,GenBank,EPR64933,,,GT1,EFPP (TGGT1_269460),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,ser/Thr phosphatase family protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19760,PHI:12150,UniProt,A0A125YNY7,GenBank,EPR59118,,,GT1,SLP (Shewanella-like phosphatases) (TGGT1_254770),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,ser/Thr phosphatase family protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19761,PHI:12154,UniProt,A0A125YZE7,GenBank,EPR63184,,,GT1,PPM3F (TGGT1_278510),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,protein phosphatase 2C domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19762,PHI:12155,UniProt,A0A125YSH7,GenBank,EPR57963,,,GT1,PPM4 (TGGT1_208500),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,PPM-type phosphatase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19763,PHI:12156,UniProt,S7WJH5,GenBank,EPR64443,,,GT1,PPM5A (TGGT1_272280),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,putative PP2C,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19764,PHI:12157,UniProt,A0A125YP33,GenBank,EPR58198,,,GT1,PPM5B (TGGT1_318660),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,putative PP2C,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19765,PHI:12158,UniProt,A0A125YQH7,GenBank,EPR57637,,,GT1,PPM6 (TGGT1_293450),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,protein phosphatase 2c containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19766,PHI:12159,UniProt,S7WA48,GenBank,EPR63794,,,GT1,PPM8 (TGGT1_218590),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,PPM-type phosphatase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19767,PHI:12160,UniProt,S7UH67,GenBank,EPR57055,,,GT1,PPM9 (TGGT1_220610),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,PPM-type phosphatase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19768,PHI:12161,UniProt,S7UJN4,GenBank,EPR57975,,,GT1,PPM12 (TGGT1_207590),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,protein phosphatase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19769,PHI:12162,UniProt,S7V2Q9,GenBank,EPR64275,,,GT1,PPM14 (TGGT1_232010),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,PPM-type phosphatase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19770,PHI:12163,UniProt,S7V479,GenBank,EPR64736,,,GT1,PPM18 (TGGT1_270190),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,PPM-type phosphatase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19771,PHI:12164,UniProt,S7USD5,GenBank,EPR60901,,,GT1,CTDSPL1 (CTD1) (TGGT1_310660),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,FCP1 homology domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19772,PHI:12165,UniProt,S7UXC5,GenBank,EPR62486,,,GT1,CTDSPL2 (CTD2) (TGGT1_263380),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,FCP1 homology domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19773,PHI:12166,UniProt,S7UV08,GenBank,EPR61600,,,GT1,CTDSPL3 (CTD3) (TGGT1_202550),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,primates,9606,Homo sapiens (related: human),HFF cell line,,,foreskin fibroblast cell line,FCP1 homology domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19774,PHI:12152,UniProt,S7UTT9,GenBank,EPR61052,,,GT1,PP5 (TGGT1_312200),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,protein-serine/threonine phosphatase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19775,PHI:12151,UniProt,S7V0E9,GenBank,EPR63297,,,GT1,PP7 (TGGT1_251850),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,protein-serine/threonine phosphatase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19776,PHI:12153,UniProt,S7WL31,GenBank,EPR64933,,,GT1,EFPP (TGGT1_269460),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,ser/Thr phosphatase family protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19777,PHI:12150,UniProt,A0A125YNY7,GenBank,EPR59118,,,GT1,SLP (Shewanella-like phosphatases) (TGGT1_254770),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,ser/Thr phosphatase family protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19778,PHI:12154,UniProt,A0A125YZE7,GenBank,EPR63184,,,GT1,PPM3F (TGGT1_278510),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,protein phosphatase 2C domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19779,PHI:12155,UniProt,A0A125YSH7,GenBank,EPR57963,,,GT1,PPM4 (TGGT1_208500),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,PPM-type phosphatase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19780,PHI:12156,UniProt,S7WJH5,GenBank,EPR64443,,,GT1,PPM5A (TGGT1_272280),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,putative PP2C,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19781,PHI:12157,UniProt,A0A125YP33,GenBank,EPR58198,,,GT1,PPM5B (TGGT1_318660),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,putative PP2C,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19782,PHI:12158,UniProt,A0A125YQH7,GenBank,EPR57637,,,GT1,PPM6 (TGGT1_293450),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,protein phosphatase 2c containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19783,PHI:12159,UniProt,S7WA48,GenBank,EPR63794,,,GT1,PPM8 (TGGT1_218590),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,PPM-type phosphatase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19784,PHI:12160,UniProt,S7UH67,GenBank,EPR57055,,,GT1,PPM9 (TGGT1_220610),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,PPM-type phosphatase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19785,PHI:12161,UniProt,S7UJN4,GenBank,EPR57975,,,GT1,PPM12 (TGGT1_207590),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,protein phosphatase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19786,PHI:12162,UniProt,S7V2Q9,GenBank,EPR64275,,,GT1,PPM14 (TGGT1_232010),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,PPM-type phosphatase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19787,PHI:12163,UniProt,S7V479,GenBank,EPR64736,,,GT1,PPM18 (TGGT1_270190),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,PPM-type phosphatase domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19788,PHI:12164,UniProt,S7USD5,GenBank,EPR60901,,,GT1,CTDSPL1 (CTD1) (TGGT1_310660),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,FCP1 homology domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19789,PHI:12165,UniProt,S7UXC5,GenBank,EPR62486,,,GT1,CTDSPL2 (CTD2) (TGGT1_263380),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,FCP1 homology domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19790,PHI:12166,UniProt,S7UV08,GenBank,EPR61600,,,GT1,CTDSPL3 (CTD3) (TGGT1_202550),,,,,,,5811,Toxoplasma gondii,383379,type I RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,FCP1 homology domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19791,PHI:12150,UniProt,A0A125YNY7,GenBank,EPR59118,,,GT1,SLP (Shewanella-like phosphatases) (TGGT1_254770),,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,ser/Thr phosphatase family protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19792,PHI:12151,UniProt,S7V0E9,GenBank,EPR63297,,,GT1,PP7 (TGGT1_251850),,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain,protein-serine/threonine phosphatase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,YVS,35083211,PubMed,10.3389/fcell.2021.738794,Front Cell Dev Biol. 2022 Jan 10;9:738794,xingquanzhu1@hotmail.com,"No significant differences were observed between 16 RHΔpsp strains. However, RHΔpp7 exhibited significantly lower invasion efficiency and parasitophorous vacuole formation in vitro, and less virulence in mice.",Q L Liang 2021,2021,17 genes,Liang-2021-Functional Characterization of 17 P,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19793,PHI:12167,,no data found,,,,,,vemR,,,,fleQ; ravA,UniProt: Q8P9D2; GenBank: AAM41222; UniProt: no data found; GenBank: no data found,,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,response regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19794,PHI:12168,UniProt,B0RT01,GenBank,CAP51587,,,B100,rpoN2,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,RNA polymerase sigma-54 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19795,PHI:12169,UniProt,Q8P9D2,GenBank,AAM41222,,,ATCC 33913,fleQ,,,,vemR,UniProt: no data found; GenBank: no data found,,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19796,PHI:12168,UniProt,B0RT01,GenBank,CAP51587,,,,rpoN2,,,,,,PHI:12167,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,RNA polymerase sigma-54 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19797,PHI:12167,,no data found,,,,,,vemR,,,,fleQ; ravA,UniProt: Q8P9D2; GenBank: AAM41222; UniProt: no data found; GenBank: no data found,PHI:12168,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19798,PHI:12167,,no data found,,,,,,vemR,,,,fleQ; ravA,UniProt: Q8P9D2; GenBank: AAM41222; UniProt: no data found; GenBank: no data found,PHI:12169,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19799,PHI:12169,UniProt,Q8P9D2,GenBank,AAM41222,,,,fleQ,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12167,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19800,PHI:12168,UniProt,B0RT01,GenBank,CAP51587,,,,rpoN2,,,,,,PHI:12169,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,RNA polymerase sigma-54 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19801,PHI:12169,UniProt,Q8P9D2,GenBank,AAM41222,,,,fleQ,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12168,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19802,PHI:12167,,no data found,,,,,,vemR,,,,fleQ; ravA,UniProt: Q8P9D2; GenBank: AAM41222; UniProt: no data found; GenBank: no data found,PHI:12168; PHI:12169,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19803,PHI:12168,UniProt,B0RT01,GenBank,CAP51587,,,,rpoN2,,,,,,PHI:12167; PHI:12169,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,RNA polymerase sigma-54 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19804,PHI:12169,UniProt,Q8P9D2,GenBank,AAM41222,,,,fleQ,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12167; PHI:12168,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19805,PHI:12170,,no data found,,,,,,ravA,,,,vemR,UniProt: no data found; GenBank: no data found,,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,cognate histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19806,PHI:12168,UniProt,B0RT01,GenBank,CAP51587,,,,rpoN2,,,,,,PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,RNA polymerase sigma-54 factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19807,PHI:12170,,no data found,,,,,,ravA,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12168,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,cognate histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19808,PHI:12169,UniProt,Q8P9D2,GenBank,AAM41222,,,,fleQ,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19809,PHI:12170,,no data found,,,,,,ravA,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12169,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,cognate histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19810,PHI:12167,,no data found,,,,,,vemR,,,,fleQ; ravA,UniProt: Q8P9D2; GenBank: AAM41222; UniProt: no data found; GenBank: no data found,PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,response regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19811,PHI:12170,,no data found,,,,,,ravA,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12167,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,cognate histidine kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19812,PHI:12168,UniProt,B0RT01,GenBank,CAP51587,,,,rpoN2,,,,,,PHI:12167; PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,RNA polymerase sigma-54 factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19813,PHI:12167,,no data found,,,,,,vemR,,,,fleQ; ravA,UniProt: Q8P9D2; GenBank: AAM41222; UniProt: no data found; GenBank: no data found,PHI:12168; PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19814,PHI:12170,,no data found,,,,,,ravA,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12168; PHI:12167,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,cognate histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19815,PHI:12169,UniProt,Q8P9D2,GenBank,AAM41222,,,,fleQ,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12167; PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19816,PHI:12167,,no data found,,,,,,vemR,,,,fleQ; ravA,UniProt: Q8P9D2; GenBank: AAM41222; UniProt: no data found; GenBank: no data found,PHI:12169; PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19817,PHI:12170,,no data found,,,,,,ravA,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12169; PHI:12167,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,cognate histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19818,PHI:12168,UniProt,B0RT01,GenBank,CAP51587,,,,rpoN2,,,,,,PHI:12169; PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,RNA polymerase sigma-54 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19819,PHI:12169,UniProt,Q8P9D2,GenBank,AAM41222,,,,fleQ,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12168; PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19820,PHI:12170,,no data found,,,,,,ravA,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12168; PHI:12169,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,cognate histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19821,PHI:12167,,no data found,,,,,,vemR,,,,fleQ; ravA,UniProt: Q8P9D2; GenBank: AAM41222; UniProt: no data found; GenBank: no data found,PHI:12168; PHI:12169; PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19822,PHI:12168,UniProt,B0RT01,GenBank,CAP51587,,,,rpoN2,,,,,,PHI:12167; PHI:12169; PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,RNA polymerase sigma-54 factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19823,PHI:12169,UniProt,Q8P9D2,GenBank,AAM41222,,,,fleQ,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12167; PHI:12168; PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19824,PHI:12170,,no data found,,,,,,ravA,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12167; PHI:12168; PHI:12169,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,cognate histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19825,PHI:12172,UniProt,B0RT25,GenBank,CAP51611,,,B100,ravR,,,,,,PHI:12171,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,two-component system sensor-response regulator hybrid protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19826,PHI:12171,UniProt,P22260,GenBank,AAD20599,,,Xc17,clp,,,,,,PHI:12172,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,CAP-like protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19827,PHI:12170,,no data found,,,,,,ravA,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12171,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,cognate histidine kinase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19828,PHI:12171,UniProt,P22260,GenBank,AAD20599,,,Xc17,clp,,,,,,PHI:12170,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,CAP-like protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19829,PHI:12167,,no data found,,,,,,vemR,,,,fleQ; ravA,UniProt: Q8P9D2; GenBank: AAM41222; UniProt: no data found; GenBank: no data found,PHI:12171,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,response regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19830,PHI:12171,UniProt,P22260,GenBank,AAD20599,,,Xc17,clp,,,,,,PHI:12167,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,CAP-like protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19831,PHI:12169,UniProt,Q8P9D2,GenBank,AAM41222,,,,fleQ,,,,vemR,UniProt: no data found; GenBank: no data found,PHI:12171,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19832,PHI:12171,UniProt,P22260,GenBank,AAD20599,,,Xc17,clp,,,,,,PHI:12169,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,CAP-like protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19833,PHI:12171,UniProt,P22260,GenBank,AAD20599,,,Xc17,clp,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,CAP-like protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19834,PHI:12172,UniProt,B0RT25,GenBank,CAP51611,,,B100,ravR,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004 (Δlac8),black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata cv. Wenxin,,,leaf,two-component system sensor-response regulator hybrid protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,34837306,PubMed,10.1111/mpp.13164,Mol Plant Pathol. 2022 Mar;23(3):355-369,chun_xia_li@126.com,"RavA/VemR TCS regulated FleQ activity and thus influenced the expression of motility- related genes, thereby affecting Xcc motility and virulence.",M Lin 2022,2022,6 genes,Lin-2022-The RavA_VemR two-component system pl,BATCH_110C,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19835,PHI:12173,UniProt,A0A8E6MZW1,GenBank,QVP86257,,,SGSC 2189,cueP,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,copper-binding periplasmic metallochaperone,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35369444,PubMed,10.3389/fmicb.2022.823176,Front Microbiol. 2022 Mar 16;13:823176,soncini@ibr-conicet.gov.ar,"Regardless of the presence or absence of cus, a mutant deleted of cueP showed a deficiency in replication inside macrophages compared to the wildtype strain.",A A E Méndez 2022,2022,1 gene,Méndez-2022-Evolution of Copper Homeostasis an,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19836,PHI:12174,UniProt,Q8P998,GenBank,AAM41256,,,ATCC 33913,clpA,,,,,,,339,Xanthomonas campestris,,pv. campestris strain Xc17,black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,AAA+ family ATPase subunit,,,,reduced virulence,,,,,,,,,,no,SDS; H2O2; puromycin,SDS: CHEBI:8984; H2O2: CHEBI:16240; puromycin: CHEBI:17939,,,,,gene deletion: full; gene complementation,,,YVS,35322326,PubMed,10.1007/s10482-022-01725-9,Antonie Van Leeuwenhoek. 2022 May;115(5):589-607,ymhsiao@ctust.edu.tw,"The inactivation of clpA, but not of clpS, resulted in susceptibility to high temperature and attenuated virulence in the host plant.",H H Lo 2022,2022,2 genes,Lo-2022-Expression and function of clpS and cl,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19837,PHI:12175,UniProt,Q8P999,GenBank,AAM41255,,,ATCC 33913,clpS,,,,,,,339,Xanthomonas campestris,,pv. campestris strain Xc17,black rot,eudicots,3712,Brassica oleracea (no common name found),var. capitata (cabbage),,,leaf,adaptor protein,,,,unaffected pathogenicity,,,,,,,,,,no,SDS; H2O2; puromycin,SDS: CHEBI:8984; H2O2: CHEBI:16240; puromycin: CHEBI:17939,,,,,gene deletion: full; gene complementation,,,YVS,35322326,PubMed,10.1007/s10482-022-01725-9,Antonie Van Leeuwenhoek. 2022 May;115(5):589-607,ymhsiao@ctust.edu.tw,"The inactivation of clpA, but not of clpS, resulted in susceptibility to high temperature and attenuated virulence in the host plant.",H H Lo 2022,2022,2 genes,Lo-2022-Expression and function of clpS and cl,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19838,PHI:12176,UniProt,E3QKL1,GenBank,EFQ31399,,,M1.001,Cgfl (GLRG_06543),,,,,,,31870,Colletotrichum graminicola,645133,M1.001 BH,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),Mo940 line,,,root; leaf,effector protein,,,,effector (plant avirulence determinant),,no,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,26619206,PubMed,10.1111/mpp.12347,Mol Plant Pathol. 2016 Sep;17(7):1048-62,ssukno@usal.es,"The appressorium morphology of the null mutant was normal, but they exhibited delayed development during the infection process on maize leaves and roots.",J M Sanz-Martín 2016,2016,1 gene,Sanz-Martin-2016-A highly conserved metallopro,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19839,PHI:12178,UniProt,P06200,GenBank,AE004519_4,,,PAO1,plcH,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,cystic fibrosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,hemolytic phospholipase C,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35369481,PubMed,10.3389/fmicb.2022.867449,Front Microbiol. 2022 Mar 18;13:867449,bob@hancocklab.com,The results indicated that PlcH may be targeted by liposomes to reduce virulence of P. aeruginosa in a mouse model.,H Wolfmeier 2022,2022,1 gene,Wolfmeier-2022-Targeting the Pseudomonas aerug,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19840,PHI:12179,UniProt,G4MY43,GenBank,EHA54374,,,70-15,MoFHB1 (MGG 01268),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,flavohemoglobin,,,,unaffected pathogenicity,,no,no,,,,,wild type,wild type,no,sodium nitroprusside; NaNO2; S-nitrosoglutathione,sodium nitroprusside: CHEBI:29321; NaNO2: CHEBI:78870; S-nitrosoglutathione: CHEBI:50091,,,,,gene deletion: full; gene complementation,,,YVS,35259230,PubMed,10.1093/femsle/fnab162,FEMS Microbiol Lett. 2022 Mar 11;369(1):fnab162,sungc01@sina.com,"Pathogenicity defects of the Δmosfa1Δmofhb1 mutant were due to the loss of MoSFA1, while MoFHB1 was not a critical virulence factor.",Z Zhang 2022,2022,2 genes,Zhang-2022-The flavohemoglobin gene MoFHB1 is,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19841,PHI:12180,,no data found,,,,,,MoSFA1,,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,GSNO reductase,,,,reduced virulence,,,,,,,,,,no,sodium nitroprusside; NaNO2; S-nitrosoglutathione,sodium nitroprusside: CHEBI:29321; NaNO2: CHEBI:78870; S-nitrosoglutathione: CHEBI:50091,,,,,gene deletion: full; gene complementation,,,YVS,35259230,PubMed,10.1093/femsle/fnab162,FEMS Microbiol Lett. 2022 Mar 11;369(1):fnab162,sungc01@sina.com,"Pathogenicity defects of the Δmosfa1Δmofhb1 mutant were due to the loss of MoSFA1, while MoFHB1 was not a critical virulence factor.",Z Zhang 2022,2022,2 genes,Zhang-2022-The flavohemoglobin gene MoFHB1 is,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19842,PHI:12179,UniProt,G4MY43,GenBank,EHA54374,,,70-15,MoFHB1 (MGG 01268),chromosome 2,,,,,PHI:12180,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,flavohemoglobin,,,,reduced virulence,,no,no,,,,,wild type,wild type,no,sodium nitroprusside; NaNO2; S-nitrosoglutathione,sodium nitroprusside: CHEBI:29321; NaNO2: CHEBI:78870; S-nitrosoglutathione: CHEBI:50091,,,,,gene deletion: full; gene complementation,,,YVS,35259230,PubMed,10.1093/femsle/fnab162,FEMS Microbiol Lett. 2022 Mar 11;369(1):fnab162,sungc01@sina.com,"Pathogenicity defects of the Δmosfa1Δmofhb1 mutant were due to the loss of MoSFA1, while MoFHB1 was not a critical virulence factor.",Z Zhang 2022,2022,2 genes,Zhang-2022-The flavohemoglobin gene MoFHB1 is,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19843,PHI:12180,,no data found,,,,,,MoSFA1,,,,,,PHI:12179,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,GSNO reductase,,,,reduced virulence,,,,,,,,,,no,sodium nitroprusside; NaNO2; S-nitrosoglutathione,sodium nitroprusside: CHEBI:29321; NaNO2: CHEBI:78870; S-nitrosoglutathione: CHEBI:50091,,,,,gene deletion: full; gene complementation,,,YVS,35259230,PubMed,10.1093/femsle/fnab162,FEMS Microbiol Lett. 2022 Mar 11;369(1):fnab162,sungc01@sina.com,"Pathogenicity defects of the Δmosfa1Δmofhb1 mutant were due to the loss of MoSFA1, while MoFHB1 was not a critical virulence factor.",Z Zhang 2022,2022,2 genes,Zhang-2022-The flavohemoglobin gene MoFHB1 is,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19844,PHI:12181,UniProt,E3QCQ1,GenBank,EFQ28639,,,M1.001,CgGPI7,,,,,,,31870,Colletotrichum graminicola,,CgM2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),,,,root; leaf,ethanolamine phosphate transferase,,,GPI anchor synthesis pathway,reduced virulence,,no,yes,,,reduced; aberrant,,reduced; aberrant,,no,SDS; congo red,SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,35328406,PubMed,10.3390/ijms23062985,Int J Mol Sci. 2022 Mar 10;23(6):2985,wdliu@ippcaas.cn,CgGPI7 mediated the appressorial penetration and was essential for the pathogenicity of C. graminicola.,J Mei 2022,2022,1 gene,Mei-2022-Glycosylphosphatidylinositol Anchor B,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19845,PHI:12182,UniProt,D2AJK6,GenBank,ADA76887,,,2002017,spa47,,Spa47Y274F,,,,,623,Shigella flexneri,,serotype 2a strain 2457T,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,protein-secreting ATPase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35215145,PubMed,10.3390/pathogens11020202,Pathogens. 2022 Feb 3;11(2):202,nick.dickenson@usu.edu,"Spa47Y274, but not Spa47Y398, was critical to Shigella virulence phenotype.",K D Hardy 2022,2022,1 gene,Hardy-2022-Phosphomimetic Tyrosine Mutations i,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19846,PHI:12182,UniProt,D2AJK6,GenBank,ADA76887,,,2002017,spa47,,Spa47Y274A and phosphomimetic Spa47Y274E,,,,,623,Shigella flexneri,,serotype 2a strain 2457T,shigellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,protein-secreting ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35215145,PubMed,10.3390/pathogens11020202,Pathogens. 2022 Feb 3;11(2):202,nick.dickenson@usu.edu,"Spa47Y274, but not Spa47Y398, was critical to Shigella virulence phenotype.",K D Hardy 2022,2022,1 gene,Hardy-2022-Phosphomimetic Tyrosine Mutations i,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19847,PHI:12183,UniProt,A0A2U8XEF5,GenBank,AWN56700,,,BXO43,cbsA,,cbsAΔFnIII,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,extracellular exoglucanase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35278018,PubMed,10.1111/mpp.13205,Mol Plant Pathol. 2022 Mar 12,rameshvsonti@gmail.com,"Deletion of the FnIII domain reduced virulence similar to ΔcbsA Xoo, which corroborated the importance of the FnIII domain in CbsA.",R Nathawat 2022,2022,1 gene,Nathawat-2022-Role of the FnIII domain associa,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19848,PHI:12183,UniProt,A0A2U8XEF5,GenBank,AWN56700,,,BXO43,cbsA,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Taichung Native 1,,,leaf,extracellular exoglucanase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35278018,PubMed,10.1111/mpp.13205,Mol Plant Pathol. 2022 Mar 12,rameshvsonti@gmail.com,"Deletion of the FnIII domain reduced virulence similar to ΔcbsA Xoo, which corroborated the importance of the FnIII domain in CbsA.",R Nathawat 2022,2022,1 gene,Nathawat-2022-Role of the FnIII domain associa,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19849,PHI:12184,UniProt,D3J126,GenBank,XP_018384845,,,SRC1lrK2f,AaHog1,,,,,,,5599,Alternaria alternata,,KY397985.1,brown spot,eudicots,23211,Pyrus communis (related: Pear),cv. Zaosu,,,fruit,high-osmolarity glycerol response kinase,,,,reduced virulence,,yes,yes,,,,,reduced,reduced,no,NaCl; sorbitol; SDS; Congo red,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,YVS,35330268,PubMed,10.3390/jof8030266,J Fungi (Basel). 2022 Mar 6;8(3):266,lyc@gsau.edu.cn,The ΔAaHog1 mutant significantly decreased the rates of spore germination and appressorium formation.,M Zhang 2022,2022,1 gene,Zhang-2022-AaHog1 Regulates Infective Structur,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19850,PHI:12185,,no data found,,,,,,DHCR7,,,,,,,4784,Phytophthora capsici,,BYA5,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,Δ7-sterol reductase,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35382565,PubMed,10.1098/rsob.210282,Open Biol. 2022 Apr;12(4):210282,seedling@cau.edu.cn,PcDHCR7 played a key role in mycelium development and pathogenicity of zoospores.,W Wang 2022,2022,1 gene,Wang-2022-Phytophthora capsici sterol reductas,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19851,PHI:12185,,no data found,,,,,,DHCR7,,,,,,,4784,Phytophthora capsici,,BYA5,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,Δ7-sterol reductase,,,,reduced virulence,,,,,,,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35382565,PubMed,10.1098/rsob.210282,Open Biol. 2022 Apr;12(4):210282,seedling@cau.edu.cn,PcDHCR7 played a key role in mycelium development and pathogenicity of zoospores.,W Wang 2022,2022,1 gene,Wang-2022-Phytophthora capsici sterol reductas,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19852,PHI:12186,UniProt,P0AA16,GenBank,AAC76430,,,K-12,ompR,,,,,,,562,Escherichia coli,1401689,APEC 17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryonic fibroblast cell line,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35240350,PubMed,10.1016/j.psj.2022.101757,Poult Sci. 2022 Apr;101(4):101757,qkz@ahau.edu.cn,"Inactivation of the ompR gene attenuated bacterial motility, biofilm formation, and the production of curli.",D Fu 2022,2022,1 gene,Fu-2022-The response regulator OmpR contribute,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19853,PHI:12186,UniProt,P0AA16,GenBank,AAC76430,,,K-12,ompR,,,,,,,562,Escherichia coli,1401689,APEC 17,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),,,,,response regulator,,,,reduced virulence,,,,,,,,,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35240350,PubMed,10.1016/j.psj.2022.101757,Poult Sci. 2022 Apr;101(4):101757,qkz@ahau.edu.cn,"Inactivation of the ompR gene attenuated bacterial motility, biofilm formation, and the production of curli.",D Fu 2022,2022,1 gene,Fu-2022-The response regulator OmpR contribute,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19854,PHI:12187,UniProt,Q9EXF7,GenBank,CAC20634,,,EGD,inlF,,,,,,,1639,Listeria monocytogenes,,NTSN,listeriosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"internalin, virulence factor",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35223532,PubMed,10.3389/fcimb.2021.748461,Front Cell Infect Microbiol. 2022 Feb 10;11:748461,yylan@yzu.edu.cn,InlF mediated the inhibition of the pro-in?ammatory response and contributed to the colonization and survival of Lm during the early stage of infection in mice.,Z Ling 2021,2021,1 gene,Ling-2021-inlF Enhances Listeria monocytogenes,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19855,PHI:12187,UniProt,Q9EXF7,GenBank,CAC20634,,,EGD,inlF,,,,,,,1639,Listeria monocytogenes,,NTSN,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; ileum,"internalin, virulence factor",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35223532,PubMed,10.3389/fcimb.2021.748461,Front Cell Infect Microbiol. 2022 Feb 10;11:748461,yylan@yzu.edu.cn,InlF mediated the inhibition of the pro-in?ammatory response and contributed to the colonization and survival of Lm during the early stage of infection in mice.,Z Ling 2021,2021,1 gene,Ling-2021-inlF Enhances Listeria monocytogenes,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19856,PHI:12187,UniProt,Q9EXF7,GenBank,CAC20634,,,EGD,inlF,,,,,,,1639,Listeria monocytogenes,,NTSN,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain,"internalin, virulence factor",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35223532,PubMed,10.3389/fcimb.2021.748461,Front Cell Infect Microbiol. 2022 Feb 10;11:748461,yylan@yzu.edu.cn,InlF mediated the inhibition of the pro-in?ammatory response and contributed to the colonization and survival of Lm during the early stage of infection in mice.,Z Ling 2021,2021,1 gene,Ling-2021-inlF Enhances Listeria monocytogenes,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19857,PHI:12188,,no data found,,,,,,bspC,,,,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,brain,adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35316308,PubMed,10.1371/journal.ppat.1010397,PLoS Pathog. 2022 Mar 22;18(3):e1010397,kelly.doran@cuanschutz.edu,Site directed mutagenesis identified a binding pocket necessary for GBS host cell interaction and development of meningitis.,H S Manzer 2022,2022,1 gene,Manzer-2022-Targeting the BspC-vimentin intera,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19858,PHI:12188,,no data found,,,,,,bspC,,"Two multi-point mutants with mutations within the left portion of the pocket (F267A, F269A, H271A) resulted in the mutant termed the Left Pocket Mutant (LPM), while mutations within the right portion of the pocket(F379A, K380E, H382A, and W384A) resulted in the mutant termed the Right Pocket Mutant(RPM) of the BspC V-domain V-domain pocket.",,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,brain,adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35316308,PubMed,10.1371/journal.ppat.1010397,PLoS Pathog. 2022 Mar 22;18(3):e1010397,kelly.doran@cuanschutz.edu,Site directed mutagenesis identified a binding pocket necessary for GBS host cell interaction and development of meningitis.,H S Manzer 2022,2022,1 gene,Manzer-2022-Targeting the BspC-vimentin intera,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19859,PHI:12188,,no data found,,,,,,bspC,,,,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,primates,9606,Homo sapiens (related: human),hCMEC,,,HCMEC cell,adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35316308,PubMed,10.1371/journal.ppat.1010397,PLoS Pathog. 2022 Mar 22;18(3):e1010397,kelly.doran@cuanschutz.edu,Site directed mutagenesis identified a binding pocket necessary for GBS host cell interaction and development of meningitis.,H S Manzer 2022,2022,1 gene,Manzer-2022-Targeting the BspC-vimentin intera,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19860,PHI:12188,,no data found,,,,,,bspC,,"Two multi-point mutants with mutations within the left portion of the pocket (F267A, F269A, H271A) resulted in the mutant termed the Left Pocket Mutant (LPM), while mutations within the right portion of the pocket(F379A, K380E, H382A, and W384A) resulted in the mutant termed the Right Pocket Mutant(RPM) of the BspC V-domain V-domain pocket.",,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,primates,9606,Homo sapiens (related: human),hCMEC,,,HCMEC cell,adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35316308,PubMed,10.1371/journal.ppat.1010397,PLoS Pathog. 2022 Mar 22;18(3):e1010397,kelly.doran@cuanschutz.edu,Site directed mutagenesis identified a binding pocket necessary for GBS host cell interaction and development of meningitis.,H S Manzer 2022,2022,1 gene,Manzer-2022-Targeting the BspC-vimentin intera,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19861,PHI:12188,,no data found,,,,,,bspC,,,,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,adhesin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35316308,PubMed,10.1371/journal.ppat.1010397,PLoS Pathog. 2022 Mar 22;18(3):e1010397,kelly.doran@cuanschutz.edu,Site directed mutagenesis identified a binding pocket necessary for GBS host cell interaction and development of meningitis.,H S Manzer 2022,2022,1 gene,Manzer-2022-Targeting the BspC-vimentin intera,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19862,PHI:12188,,no data found,,,,,,bspC,,"Two multi-point mutants with mutations within the left portion of the pocket (F267A, F269A, H271A) resulted in the mutant termed the Left Pocket Mutant (LPM), while mutations within the right portion of the pocket(F379A, K380E, H382A, and W384A) resulted in the mutant termed the Right Pocket Mutant(RPM) of the BspC V-domain V-domain pocket.",,,,,1311,Streptococcus agalactiae,342616,COH1,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,blood,adhesin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35316308,PubMed,10.1371/journal.ppat.1010397,PLoS Pathog. 2022 Mar 22;18(3):e1010397,kelly.doran@cuanschutz.edu,Site directed mutagenesis identified a binding pocket necessary for GBS host cell interaction and development of meningitis.,H S Manzer 2022,2022,1 gene,Manzer-2022-Targeting the BspC-vimentin intera,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19863,PHI:12189,,no data found,,,,,,ERG25,,,,,,,5478,Candida glabrata,,HETS202,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,"enzyme that demethylates 4,4-dimethylzymosterol",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,YVS,35399500,PubMed,10.3389/fcell.2022.820675,Front Cell Dev Biol. 2022 Mar 24;10:820675,chibana@faculty.chiba-u.jp,ERG25 knockdown was found to decrease lethality of infected mice.,M Okamoto 2022,2022,1 gene,Okamoto-2022-Erg25 Controls Host-Cholesterol U,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19864,PHI:12190,UniProt,Q6FUD7,GenBank,CAG59081,,,CBS 138,RIB1 (CAGL0F04279g),chromosome F,,,,,,5478,Candida glabrata,,KUE100-1,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,GTP cyclohydrolase-2,,,,reduced virulence,,,,,,,,,,no,sodium nitrite,sodium nitrite: CHEBI:78870,,,,,gene deletion: full,,,YVS,35308400,PubMed,10.3389/fmicb.2022.825121,Front Microbiol. 2022 Mar 2;13:825121,hiro@bs.naist.jp,Proliferation of C. glabrata in cultures of macrophage-like cells required the GCH2 dependent nitrosative stress detoxifying mechanism.,R Nasuno 2022,2022,1 gene,Nasuno-2022-Identification and Functional Anal,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19865,PHI:12190,UniProt,Q6FUD7,GenBank,CAG59081,,,CBS 138,RIB1 (CAGL0F04279g),chromosome F,,,,,,5478,Candida glabrata,,KUE100-1,invasive candidiasis,moths,7091,Bombyx mori (related: domestic silkworm),,,,,GTP cyclohydrolase-2,,,,reduced virulence,,,,,,,,,,no,sodium nitrite,sodium nitrite: CHEBI:78870,,,,,gene deletion: full,,,YVS,35308400,PubMed,10.3389/fmicb.2022.825121,Front Microbiol. 2022 Mar 2;13:825121,hiro@bs.naist.jp,Proliferation of C. glabrata in cultures of macrophage-like cells required the GCH2 dependent nitrosative stress detoxifying mechanism.,R Nasuno 2022,2022,1 gene,Nasuno-2022-Identification and Functional Anal,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19866,PHI:12191,UniProt,I1RRS3,GenBank,CEF84091,,,PH-1,FgAtrR (FGSG_06810),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,inflorescence,Zn(II)2-Cys6 transcription factor,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,reduced,reduced,reduced; aberrant,,no,prochloraz; propiconazole,prochloraz: CHEBI:8434; propiconazole: CHEBI:8489,,,,,gene deletion: full; gene complementation,,,YVS,35205191,PubMed,10.3390/biology11020326,Biology (Basel). 2022 Feb 18;11(2):326,jghuang@qau.edu.cn,"The pathogenicity of the ΔFgAtrR mutant on wheat spikes and corn silks was severely impaired with reduced deoxynivalenol production, while the tolerance to prochloraz and propiconazole of the deletion mutant was also significantly decreased.",Y Zhao 2022,2022,1 gene,Zhao-2022-The Transcription Factor FgAtrR Regu,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19867,PHI:12191,UniProt,I1RRS3,GenBank,CEF84091,,,PH-1,FgAtrR (FGSG_06810),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),cv. Zhengdan 958,,,kernel,Zn(II)2-Cys6 transcription factor,,,deoxynivalenol biosynthesis,reduced virulence,,,,,,reduced,reduced,reduced; aberrant,,no,prochloraz; propiconazole,prochloraz: CHEBI:8434; propiconazole: CHEBI:8489,,,,,gene deletion: full; gene complementation,,,YVS,35205191,PubMed,10.3390/biology11020326,Biology (Basel). 2022 Feb 18;11(2):326,jghuang@qau.edu.cn,"The pathogenicity of the ΔFgAtrR mutant on wheat spikes and corn silks was severely impaired with reduced deoxynivalenol production, while the tolerance to prochloraz and propiconazole of the deletion mutant was also significantly decreased.",Y Zhao 2022,2022,1 gene,Zhao-2022-The Transcription Factor FgAtrR Regu,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19868,PHI:12192,UniProt,G1XLI4,GenBank,EGX45997,,,ATCC 24927,Aossk1 (AOL_s00112g14),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,response regulator,,,,increased virulence (hypervirulence),,,,,,reduced; aberrant,,reduced; aberrant,,no,sorbitol; NaCl,sorbitol: CHEBI:30911; NaCl: CHEBI:26710,,,,,gene deletion: full,,,YVS,35330262,PubMed,10.3390/jof8030260,J Fungi (Basel). 2022 Mar 3;8(3):260,jinkui960@ynu.edu.cn,The loss of Aossk1 resulted in a remarkable increase in trap formation and predation efficiency.,K X Jiang 2022,2022,1 gene,"Jiang-2022-AoSsk1, a Response Regulator Requir",BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19869,PHI:12193,,no data found,,,,,,Psg_2795,,,,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Jifeng 1,,,leaf,periplasmic chaperone protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35246805,PubMed,10.1007/s12275-022-1469-5,J Microbiol. 2022 Mar 4,jiegao115@126.com,"Mutation and knockout of Psg_2795 resulted in a reduced virulence phenotype on soybean, decreased motility, weakened bacterial attachment to a glass surface and delayed the population growth within soybean leaves.",X Wang 2022,2022,1 gene,Wang-2022-The periplasmic chaperone protein Ps,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19870,PHI:12193,,no data found,,,,,,Psg_2795,,"low-virulent mini-Tn5 mutant, designated as 4573",,,,,29438,Pseudomonas savastanoi,,pv. glycinea strain Psg,knot (olive),eudicots,3847,Glycine max (related: soybean),cv. Jifeng 1,,,leaf,periplasmic chaperone protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,YVS,35246805,PubMed,10.1007/s12275-022-1469-5,J Microbiol. 2022 Mar 4,jiegao115@126.com,"Mutation and knockout of Psg_2795 resulted in a reduced virulence phenotype on soybean, decreased motility, weakened bacterial attachment to a glass surface and delayed the population growth within soybean leaves.",X Wang 2022,2022,1 gene,Wang-2022-The periplasmic chaperone protein Ps,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19871,PHI:12194,UniProt,A0A177DCJ2,GenBank,OAG17425,,,SRC1lrK2f,veA,,,,,,,5599,Alternaria alternata,,P3,brown spot,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,velvet protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,YVS,35250954,PubMed,10.3389/fmicb.2022.842268,Front Microbiol. 2022 Feb 18;13:842268,wangm@brcast.org.cn,The absence of AaVeA caused the marked reduction of hyphae extension and conidiophore formation even though red light could not induce more spores in ΔAaVeA mutant.,L Wang 2022,2022,1 gene,Wang-2022-Roles of AaVeA on Mycotoxin Producti,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19872,PHI:12195,,no data found,,,,,,Cghsf1,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,heat shock transcription factor,,,melanin biosynthesis pathway,lethal,,,,,,,,,,yes,,,,,,,gene deletion: full,,,YVS,35205929,PubMed,10.3390/jof8020175,J Fungi (Basel). 2022 Feb 11;8(2):175,anbang@hainanu.edu.cn,"The mutant showed significant decrease in the pathogenicity repression of appressorium formation, and severe defects in melanin biosynthesis.",X Gao 2022,2022,1 gene,Gao-2022-Heat Shock Transcription Factor CgHSF,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19873,PHI:12195,,no data found,,,,,,Cghsf1,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,heat shock transcription factor,,,melanin biosynthesis pathway,reduced virulence,,yes,yes,,,,,,wild type,no,,,,,,,gene mutation,,,YVS,35205929,PubMed,10.3390/jof8020175,J Fungi (Basel). 2022 Feb 11;8(2):175,anbang@hainanu.edu.cn,"The mutant showed significant decrease in the pathogenicity repression of appressorium formation, and severe defects in melanin biosynthesis.",X Gao 2022,2022,1 gene,Gao-2022-Heat Shock Transcription Factor CgHSF,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19874,PHI:12196,UniProt,A0A384K316,GenBank,ATZ57171,,,B05.10,Bcsnf1 (Bcin14g03370),BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Saxa,,,leaf,non-specific serine/threonine protein kinase,,,,reduced virulence,,,no,,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35208900,PubMed,10.3390/microorganisms10020444,Microorganisms. 2022 Feb 15;10(2):444,luca.sella@unipd.it,The Δsnf1 mutants were altered in their ability to control ambient pH.,S Lengyel 2022,2022,1 gene,Lengyel-2022-Snf1 Kinase Differentially Regula,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19875,PHI:12196,UniProt,A0A384K316,GenBank,ATZ57171,,,B05.10,Bcsnf1 (Bcin14g03370),BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),cv. Petit vert de Paris,,,leaf,non-specific serine/threonine protein kinase,,,,reduced virulence,,,no,,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35208900,PubMed,10.3390/microorganisms10020444,Microorganisms. 2022 Feb 15;10(2):444,luca.sella@unipd.it,The Δsnf1 mutants were altered in their ability to control ambient pH.,S Lengyel 2022,2022,1 gene,Lengyel-2022-Snf1 Kinase Differentially Regula,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19876,PHI:12196,UniProt,A0A384K316,GenBank,ATZ57171,,,B05.10,Bcsnf1 (Bcin14g03370),BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious,,,fruit,non-specific serine/threonine protein kinase,,,,reduced virulence,,,no,,,reduced; aberrant,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35208900,PubMed,10.3390/microorganisms10020444,Microorganisms. 2022 Feb 15;10(2):444,luca.sella@unipd.it,The Δsnf1 mutants were altered in their ability to control ambient pH.,S Lengyel 2022,2022,1 gene,Lengyel-2022-Snf1 Kinase Differentially Regula,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19877,PHI:12197,UniProt,no data found,GenBank,,,,,VdRTX1 (VEDA_03750),,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,35363930,PubMed,10.1111/mpp.13213,Mol Plant Pathol. 2022 Apr 1,daixiaofeng_caas@126.com,Knockout of VdRTX1 significantly enhanced V. dahliae virulence on tobacco while V. dahliae employs the known suppressor VdCBM1 to escape the immunity induced by VdRTX1.,C M Yin 2022,2022,1 gene,Yin-2022-A secreted ribonuclease effector from,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19878,PHI:12197,UniProt,no data found,GenBank,,,,,VdRTX1 (VEDA_03750),,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35363930,PubMed,10.1111/mpp.13213,Mol Plant Pathol. 2022 Apr 1,daixiaofeng_caas@126.com,Knockout of VdRTX1 significantly enhanced V. dahliae virulence on tobacco while V. dahliae employs the known suppressor VdCBM1 to escape the immunity induced by VdRTX1.,C M Yin 2022,2022,1 gene,Yin-2022-A secreted ribonuclease effector from,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19879,PHI:12197,UniProt,no data found,GenBank,,,,,VdRTX1 (VEDA_03750),,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,35363930,PubMed,10.1111/mpp.13213,Mol Plant Pathol. 2022 Apr 1,daixiaofeng_caas@126.com,Knockout of VdRTX1 significantly enhanced V. dahliae virulence on tobacco while V. dahliae employs the known suppressor VdCBM1 to escape the immunity induced by VdRTX1.,C M Yin 2022,2022,1 gene,Yin-2022-A secreted ribonuclease effector from,BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19880,PHI:12198,UniProt,Q8E0T8,GenBank,AE014219_20,,,2603V/R,Psr,,,,,,,1311,Streptococcus agalactiae,,GBS 515,pneumonia; meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,LCP family protein,,,,reduced virulence,,,,,,,,reduced,,no,triton X-100; penicillin,Triton X-100: CHEBI:9750; penicillin: CHEBI:17334,,,,,gene deletion: full; gene complementation,,,YVS,35208672,PubMed,10.3390/microorganisms10020217,Microorganisms. 2022 Jan 20;10(2):217,melody.neely@maine.edu,"The absence of Psr results in a decreased growth rate, decreased viability over time, inconsistent cocci morphology and diminished cell wall integrity, as well as an increased penicillin susceptibility, decreased capsule levels and attenuation in virulence in a zebra?sh model of infectious disease.",A Rajaei 2022,2022,2 genes,"Rajaei-2022-The LCP Family Protein, Psr, Is Re",BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19881,PHI:12199,UniProt,Q8DZD3,GenBank,AE014245_15,,,2603V/R,cpsA,,,,,,,1311,Streptococcus agalactiae,,GBS 515,pneumonia; meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,capsular polysaccharide biosynthesis protein,,,,reduced virulence,,,,,,,,wild type,,no,triton X-100; penicillin,Triton X-100: CHEBI:9750; penicillin: CHEBI:17334,,,,,gene deletion: full; gene complementation,,,YVS,35208672,PubMed,10.3390/microorganisms10020217,Microorganisms. 2022 Jan 20;10(2):217,melody.neely@maine.edu,"The absence of Psr results in a decreased growth rate, decreased viability over time, inconsistent cocci morphology and diminished cell wall integrity, as well as an increased penicillin susceptibility, decreased capsule levels and attenuation in virulence in a zebra?sh model of infectious disease.",A Rajaei 2022,2022,2 genes,"Rajaei-2022-The LCP Family Protein, Psr, Is Re",BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19882,PHI:12198,UniProt,Q8E0T8,GenBank,AE014219_20,,,2603V/R,Psr,,,,,,PHI:12199,1311,Streptococcus agalactiae,,GBS 515,pneumonia; meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,LCP family protein,,,,reduced virulence,,,,,,,,reduced,,no,triton X-100; penicillin,Triton X-100: CHEBI:9750; penicillin: CHEBI:17334,,,,,gene deletion: full; gene complementation,,,YVS,35208672,PubMed,10.3390/microorganisms10020217,Microorganisms. 2022 Jan 20;10(2):217,melody.neely@maine.edu,"The absence of Psr results in a decreased growth rate, decreased viability over time, inconsistent cocci morphology and diminished cell wall integrity, as well as an increased penicillin susceptibility, decreased capsule levels and attenuation in virulence in a zebra?sh model of infectious disease.",A Rajaei 2022,2022,2 genes,"Rajaei-2022-The LCP Family Protein, Psr, Is Re",BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19883,PHI:12199,UniProt,Q8DZD3,GenBank,AE014245_15,,,2603V/R,cpsA,,,,,,PHI:12198,1311,Streptococcus agalactiae,,GBS 515,pneumonia; meningitis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,capsular polysaccharide biosynthesis protein,,,,reduced virulence,,,,,,,,reduced,,no,triton X-100; penicillin,Triton X-100: CHEBI:9750; penicillin: CHEBI:17334,,,,,gene deletion: full; gene complementation,,,YVS,35208672,PubMed,10.3390/microorganisms10020217,Microorganisms. 2022 Jan 20;10(2):217,melody.neely@maine.edu,"The absence of Psr results in a decreased growth rate, decreased viability over time, inconsistent cocci morphology and diminished cell wall integrity, as well as an increased penicillin susceptibility, decreased capsule levels and attenuation in virulence in a zebra?sh model of infectious disease.",A Rajaei 2022,2022,2 genes,"Rajaei-2022-The LCP Family Protein, Psr, Is Re",BATCH_111A,2022-04-01,MC,,,,,,,,,,,,,
,,Record 19884,PHI:12200,UniProt,no data found,GenBank,QQG68109,,,Ea1189,csrD,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,RNase E specificity factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19885,PHI:12201,UniProt,no data found,GenBank,,,,,pdeA,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19886,PHI:12202,UniProt,no data found,GenBank,,,,,pdeB,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19887,PHI:12203,UniProt,no data found,GenBank,,,,,pdeC,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19888,PHI:12200,UniProt,no data found,GenBank,QQG68109,,,Ea1189,csrD,,,,,,PHI:12201; PHI:12202; PHI:12203,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,RNase E specificity factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19889,PHI:12201,UniProt,no data found,GenBank,,,,,pdeA,,,,,,PHI:12200; PHI:12202; PHI:12203,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19890,PHI:12202,UniProt,no data found,GenBank,,,,,pdeB,,,,,,PHI:12200; PHI:12201; PHI:12203,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19891,PHI:12203,UniProt,no data found,GenBank,,,,,pdeC,,,,,,PHI:12200; PHI:12201; PHI:12202,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19892,PHI:12200,UniProt,no data found,GenBank,QQG68109,,,Ea1189,csrD,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,RNase E specificity factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19893,PHI:12201,UniProt,no data found,GenBank,,,,,pdeA,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19894,PHI:12202,UniProt,no data found,GenBank,,,,,pdeB,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19895,PHI:12203,UniProt,no data found,GenBank,,,,,pdeC,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19896,PHI:12200,UniProt,no data found,GenBank,QQG68109,,,Ea1189,csrD,,,,,,PHI:12201; PHI:12202; PHI:12203,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,RNase E specificity factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19897,PHI:12201,UniProt,no data found,GenBank,,,,,pdeA,,,,,,PHI:12200; PHI:12202; PHI:12203,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19898,PHI:12202,UniProt,no data found,GenBank,,,,,pdeB,,,,,,PHI:12200; PHI:12201; PHI:12203,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19899,PHI:12203,UniProt,no data found,GenBank,,,,,pdeC,,,,,,PHI:12200; PHI:12201; PHI:12202,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35396793,PubMed,10.1111/mpp.13217,Mol Plant Pathol. 2022 Apr 9,sundin@msu.edu,CsrD was found to positively contribute to virulence and biofilm formation.,R R Kharadi 2022,2022,4 genes,Kharadi-2022-CsrD regulates amylovoran biosynt,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19900,PHI:12204,UniProt,no data found,GenBank,,,,,PpAGO3,,PpAGO3ΔRGG1 and PpAGO3ΔRGG3 mutants that carries a deletion of copies of the N-terminal RGG motif (QRGGYD),,,,,4792,Phytophthora nicotianae,,PpBS042,black shank (tobacco),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,argonaute (AGO) protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35401482,PubMed,10.3389/fmicb.2022.856106,Front Microbiol. 2022 Mar 24;13:856106,wxshan@nwafu.edu.cn,"Transient overexpression of the upregulated RXLR effector genes, PPTG_01869 and PPTG_15425 identified in the mutants PpAGO3ΔRGG1 and PpAGO3ΔRGG3, strongly enhanced N. benthamiana susceptibility to P. parasitica. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae'",J Xu 2022,2022,3 genes,Xu-2022-Mutations in PpAGO3 Lead to Enhanced V,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19901,PHI:12204,UniProt,no data found,GenBank,,,,,PpAGO3,,PpAGO3ΔRGG1 and PpAGO3ΔRGG3 mutants that carries a deletion of copies of the N-terminal RGG motif (QRGGYD),,,,,4792,Phytophthora nicotianae,,PpBS042,black shank (tobacco),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,argonaute (AGO) protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35401482,PubMed,10.3389/fmicb.2022.856106,Front Microbiol. 2022 Mar 24;13:856106,wxshan@nwafu.edu.cn,"Transient overexpression of the upregulated RXLR effector genes, PPTG_01869 and PPTG_15425 identified in the mutants PpAGO3ΔRGG1 and PpAGO3ΔRGG3, strongly enhanced N. benthamiana susceptibility to P. parasitica. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae'",J Xu 2022,2022,3 genes,Xu-2022-Mutations in PpAGO3 Lead to Enhanced V,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19902,PHI:12205,UniProt,W2RAR9,GenBank,ETN21769,,,INRA-310,PPTG_01869,,,,,,,4792,Phytophthora nicotianae,,PpBS042,black shank (tobacco),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; other evidence: transgenic plants,,,YVS,35401482,PubMed,10.3389/fmicb.2022.856106,Front Microbiol. 2022 Mar 24;13:856106,wxshan@nwafu.edu.cn,"Transient overexpression of the upregulated RXLR effector genes, PPTG_01869 and PPTG_15425 identified in the mutants PpAGO3ΔRGG1 and PpAGO3ΔRGG3, strongly enhanced N. benthamiana susceptibility to P. parasitica. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae'",J Xu 2022,2022,3 genes,Xu-2022-Mutations in PpAGO3 Lead to Enhanced V,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19903,PHI:12206,UniProt,W2PVL9,GenBank,ETN04070,,,INRA-310,PPTG_15425,,,,,,,4792,Phytophthora nicotianae,,PpBS042,black shank (tobacco),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; other evidence: transgenic plants,,,YVS,35401482,PubMed,10.3389/fmicb.2022.856106,Front Microbiol. 2022 Mar 24;13:856106,wxshan@nwafu.edu.cn,"Transient overexpression of the upregulated RXLR effector genes, PPTG_01869 and PPTG_15425 identified in the mutants PpAGO3ΔRGG1 and PpAGO3ΔRGG3, strongly enhanced N. benthamiana susceptibility to P. parasitica. pathogen species name change for 4.17 from 'Phytophthora parasitica' to 'Phytophthora nicotianae'",J Xu 2022,2022,3 genes,Xu-2022-Mutations in PpAGO3 Lead to Enhanced V,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19904,PHI:12207,UniProt,P0CL08,GenBank,AAL21755,,,LT2; SGSC 1412; ATCC 700720,hilD,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,AraC-like transcription factor,,,,reduced virulence,,,,,,,,,,no,tris EDTA; sodium cholate,tris EDTA CAS no.: CAS:38641-82-6; sodium cholate: CHEBI:26711,,,,,gene deletion: full,,,YVS,35389980,PubMed,10.1371/journal.pbio.3001608,PLoS Biol. 2022 Apr 7;20(4):e3001608,mederic.diard@unibas.ch,Pretreating the bacteria with sublethal stress inhibited virulence expression and increased stress resistance.,M Sobota 2022,2022,1 gene,Sobota-2022-The expression of virulence genes,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19905,PHI:12208,UniProt,A0A655P240,GenBank,CRZ89434,,,A51,tagH,,,,,,,666,Vibrio cholerae,,S2CHK17,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,erythrocyte,O-antigen export system ATP-binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19906,PHI:12208,UniProt,A0A655P240,GenBank,CRZ89434,,,A51,tagH,,,,,,PHI:12209,666,Vibrio cholerae,,S2CHK17,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,erythrocyte,O-antigen export system ATP-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19907,PHI:12209,UniProt,P09545,GenBank,CAA68637,,,017,hlyA,,,,,,PHI:12208,666,Vibrio cholerae,,S2CHK17,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,erythrocyte,hemolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19908,PHI:12208,UniProt,A0A655P240,GenBank,CRZ89434,,,A51,tagH,,,,,,,666,Vibrio cholerae,,S2CHK17,cholera,primates,9606,Homo sapiens (related: human),SW480 cell line,,,SW-480 cell,O-antigen export system ATP-binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19909,PHI:12208,UniProt,A0A655P240,GenBank,CRZ89434,,,A51,tagH,,,,,,PHI:12209,666,Vibrio cholerae,,S2CHK17,cholera,primates,9606,Homo sapiens (related: human),SW480 cell line,,,SW-480 cell,O-antigen export system ATP-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19910,PHI:12209,UniProt,P09545,GenBank,CAA68637,,,017,hlyA,,,,,,PHI:12208,666,Vibrio cholerae,,S2CHK17,cholera,primates,9606,Homo sapiens (related: human),SW480 cell line,,,SW-480 cell,hemolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19911,PHI:12208,UniProt,A0A655P240,GenBank,CRZ89434,,,A51,tagH,,,,,,,666,Vibrio cholerae,,S2CHK17,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ileal loop; blood,O-antigen export system ATP-binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19912,PHI:12208,UniProt,A0A655P240,GenBank,CRZ89434,,,A51,tagH,,,,,,PHI:12209,666,Vibrio cholerae,,S2CHK17,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ileal loop; blood,O-antigen export system ATP-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19913,PHI:12209,UniProt,P09545,GenBank,CAA68637,,,017,hlyA,,,,,,PHI:12208,666,Vibrio cholerae,,S2CHK17,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ileal loop; blood,hemolysin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19914,PHI:12208,UniProt,A0A655P240,GenBank,CRZ89434,,,A51,tagH,,,,,,PHI:12210,666,Vibrio cholerae,,S2CHK17,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ileal loop; blood,O-antigen export system ATP-binding protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19915,PHI:12210,UniProt,Q9KMU6,GenBank,AAF96135,,,N16961,prtV,,,,,,PHI:12208,666,Vibrio cholerae,,S2CHK17,cholera,rabbits and hares,9986,Oryctolagus cuniculus (related: rabbit),New Zealand White,,,ileal loop; blood,pre-pro-metalloprotease,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35383540,PubMed,10.1080/19490976.2022.2055440,Gut Microbes. 2022 Jan-Dec;14(1):2055440,minxunzmu@163.com,"The tagH deletion mutant enhanced the enterotoxicity of V. cholerae, which mainly depends on HlyA, and that PrtV has a weaker effect.",G Wang 2022,2022,3 genes,Wang-2022-Type VI secretion system-associated,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19916,PHI:12211,,no data found,GenBank,KZL37467,,,MB03,zapE (VT47_19690),,,,,,,317,Pseudomonas syringae,,MB03,bacterial speck,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,gut,putative ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35356513,PubMed,10.3389/fmicb.2022.826962,Front Microbiol. 2022 Mar 9;13:826962,lilin@mail.hzau.edu.cn,Results showed that P. syringae strain MB03 could kill C. elegans in the liquid assay by gut colonization.,M Ali 2022,2022,7 genes,Ali-2022-Identification of the Genes of the Pl,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19917,PHI:12212,,no data found,GenBank,KZL39494,,,MB03,acnA (VT47_09995),,,,,,,317,Pseudomonas syringae,,MB03,bacterial speck,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,gut,aconitate hydratase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35356513,PubMed,10.3389/fmicb.2022.826962,Front Microbiol. 2022 Mar 9;13:826962,lilin@mail.hzau.edu.cn,Results showed that P. syringae strain MB03 could kill C. elegans in the liquid assay by gut colonization.,M Ali 2022,2022,7 genes,Ali-2022-Identification of the Genes of the Pl,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19918,PHI:12213,,no data found,GenBank,KZL40939,,,MB03,oprD (VT47_06900),,,,,,,317,Pseudomonas syringae,,MB03,bacterial speck,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,gut,outer membrane porin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35356513,PubMed,10.3389/fmicb.2022.826962,Front Microbiol. 2022 Mar 9;13:826962,lilin@mail.hzau.edu.cn,Results showed that P. syringae strain MB03 could kill C. elegans in the liquid assay by gut colonization.,M Ali 2022,2022,7 genes,Ali-2022-Identification of the Genes of the Pl,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19919,PHI:12214,,no data found,GenBank,KZL37458,,,MB03,VT47_19645,,,,,,,317,Pseudomonas syringae,,MB03,bacterial speck,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,gut,lipoprotein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35356513,PubMed,10.3389/fmicb.2022.826962,Front Microbiol. 2022 Mar 9;13:826962,lilin@mail.hzau.edu.cn,Results showed that P. syringae strain MB03 could kill C. elegans in the liquid assay by gut colonization.,M Ali 2022,2022,7 genes,Ali-2022-Identification of the Genes of the Pl,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19920,PHI:12215,,no data found,GenBank,KZL40945,,,MB03,VT47_06935,,,,,,,317,Pseudomonas syringae,,MB03,bacterial speck,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,gut,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35356513,PubMed,10.3389/fmicb.2022.826962,Front Microbiol. 2022 Mar 9;13:826962,lilin@mail.hzau.edu.cn,Results showed that P. syringae strain MB03 could kill C. elegans in the liquid assay by gut colonization.,M Ali 2022,2022,7 genes,Ali-2022-Identification of the Genes of the Pl,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19921,PHI:12216,,no data found,GenBank,KZL42344,,,MB03,VT47_00795,,,,,,,317,Pseudomonas syringae,,MB03,bacterial speck,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,gut,glutamate: protein symporter,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35356513,PubMed,10.3389/fmicb.2022.826962,Front Microbiol. 2022 Mar 9;13:826962,lilin@mail.hzau.edu.cn,Results showed that P. syringae strain MB03 could kill C. elegans in the liquid assay by gut colonization.,M Ali 2022,2022,7 genes,Ali-2022-Identification of the Genes of the Pl,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19922,PHI:12217,,no data found,GenBank,KZL36278,,,MB03,VT47_23445,,,,,,,317,Pseudomonas syringae,,MB03,bacterial speck,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,gut,hypothetical protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35356513,PubMed,10.3389/fmicb.2022.826962,Front Microbiol. 2022 Mar 9;13:826962,lilin@mail.hzau.edu.cn,Results showed that P. syringae strain MB03 could kill C. elegans in the liquid assay by gut colonization.,M Ali 2022,2022,7 genes,Ali-2022-Identification of the Genes of the Pl,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19923,PHI:12218,UniProt,A0A391DK74,GenBank,QJR31247,,,SA01,adsA,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),U-937 cell line,,,macrophage,purine salvage pathway,,,purine salvage pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35355997,PubMed,10.3389/fimmu.2022.847171,Front Immunol. 2022 Mar 10;13:847171,winstel.volker@mh-hannover.de,"AdsA-derived dGuo and dAdo boosts macrophage cell death, indicating that S. aureus multiplexes death-effector deoxyribonucleosides to maximize intra-host survival.",E Tantawy 2022,2022,1 gene,Tantawy-2022-Staphylococcus aureus Multiplexes,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19924,PHI:12218,UniProt,A0A391DK74,GenBank,QJR31247,,,SA01,adsA,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,purine salvage pathway,,,purine salvage pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35355997,PubMed,10.3389/fimmu.2022.847171,Front Immunol. 2022 Mar 10;13:847171,winstel.volker@mh-hannover.de,"AdsA-derived dGuo and dAdo boosts macrophage cell death, indicating that S. aureus multiplexes death-effector deoxyribonucleosides to maximize intra-host survival.",E Tantawy 2022,2022,1 gene,Tantawy-2022-Staphylococcus aureus Multiplexes,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19925,PHI:12219,UniProt,Q87W42,GenBank,AAO58163,,,DC3000,HopG1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35354887,PubMed,10.1038/s41598-022-09335-1,Sci Rep. 2022 Mar 30;12(1):5388,cr022@uark.edu,"The mitochondrial-localized T3E HopG1, suppresses plant defense responses and promotes the development of disease symptoms. Host gene alteration data available for AtNHR2B.",C Rodríguez-Puerto 2022,2022,1 gene,Rodríguez-Puert-2022-The Pseudomonas syringae,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19926,PHI:12219,UniProt,Q87W42,GenBank,AAO58163,,,DC3000,HopG1,,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck (tomato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,YVS,35354887,PubMed,10.1038/s41598-022-09335-1,Sci Rep. 2022 Mar 30;12(1):5388,cr022@uark.edu,"The mitochondrial-localized T3E HopG1, suppresses plant defense responses and promotes the development of disease symptoms. Host gene alteration data available for AtNHR2B.",C Rodríguez-Puerto 2022,2022,1 gene,Rodríguez-Puert-2022-The Pseudomonas syringae,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19927,PHI:12220,UniProt,Q6EZC2,GenBank,AAT68785,,,98NK2,subA,,,,,,PHI:12221,562,Escherichia coli,,STEC O113:H21,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; colon,subtilase cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35345462,PubMed,10.1016/j.isci.2022.104050,iScience. 2022 Mar 10;25(4):104050,tsutsuki@kumamoto-u.ac.jp,The murine model of SubAB-producing Citrobacter rodentium demonstrated that SubAB promoted C. rodentium proliferation and worsened symptoms such as intestinal hyperplasia and diarrhea.,H Tsutsuki 2022,2022,2 genes,Tsutsuki-2022-Subtilase cytotoxin from Shiga-t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19928,PHI:12221,UniProt,Q6EZC3,GenBank,AAT68784,,,98NK2,subB,,,,,,PHI:12220,562,Escherichia coli,,STEC O113:H21,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; colon,subtilase cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35345462,PubMed,10.1016/j.isci.2022.104050,iScience. 2022 Mar 10;25(4):104050,tsutsuki@kumamoto-u.ac.jp,The murine model of SubAB-producing Citrobacter rodentium demonstrated that SubAB promoted C. rodentium proliferation and worsened symptoms such as intestinal hyperplasia and diarrhea.,H Tsutsuki 2022,2022,2 genes,Tsutsuki-2022-Subtilase cytotoxin from Shiga-t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19929,PHI:12220,UniProt,Q6EZC2,GenBank,AAT68785,,,98NK2,subA,,catalytically inactive mutant,,,,PHI:12221,562,Escherichia coli,,STEC O113:H21,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; colon,subtilase cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35345462,PubMed,10.1016/j.isci.2022.104050,iScience. 2022 Mar 10;25(4):104050,tsutsuki@kumamoto-u.ac.jp,The murine model of SubAB-producing Citrobacter rodentium demonstrated that SubAB promoted C. rodentium proliferation and worsened symptoms such as intestinal hyperplasia and diarrhea.,H Tsutsuki 2022,2022,2 genes,Tsutsuki-2022-Subtilase cytotoxin from Shiga-t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19930,PHI:12221,UniProt,Q6EZC3,GenBank,AAT68784,,,98NK2,subB,,catalytically inactive mutant,,,,PHI:12220,562,Escherichia coli,,STEC O113:H21,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; colon,subtilase cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35345462,PubMed,10.1016/j.isci.2022.104050,iScience. 2022 Mar 10;25(4):104050,tsutsuki@kumamoto-u.ac.jp,The murine model of SubAB-producing Citrobacter rodentium demonstrated that SubAB promoted C. rodentium proliferation and worsened symptoms such as intestinal hyperplasia and diarrhea.,H Tsutsuki 2022,2022,2 genes,Tsutsuki-2022-Subtilase cytotoxin from Shiga-t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19931,PHI:12220,UniProt,Q6EZC2,GenBank,AAT68785,,,98NK2,subA,,,,,,PHI:12221,562,Escherichia coli,,STEC O113:H21,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),J774.1 cell line,,,macrophage,subtilase cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35345462,PubMed,10.1016/j.isci.2022.104050,iScience. 2022 Mar 10;25(4):104050,tsutsuki@kumamoto-u.ac.jp,The murine model of SubAB-producing Citrobacter rodentium demonstrated that SubAB promoted C. rodentium proliferation and worsened symptoms such as intestinal hyperplasia and diarrhea.,H Tsutsuki 2022,2022,2 genes,Tsutsuki-2022-Subtilase cytotoxin from Shiga-t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19932,PHI:12221,UniProt,Q6EZC3,GenBank,AAT68784,,,98NK2,subB,,,,,,PHI:12220,562,Escherichia coli,,STEC O113:H21,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),J774.1 cell line,,,macrophage,subtilase cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35345462,PubMed,10.1016/j.isci.2022.104050,iScience. 2022 Mar 10;25(4):104050,tsutsuki@kumamoto-u.ac.jp,The murine model of SubAB-producing Citrobacter rodentium demonstrated that SubAB promoted C. rodentium proliferation and worsened symptoms such as intestinal hyperplasia and diarrhea.,H Tsutsuki 2022,2022,2 genes,Tsutsuki-2022-Subtilase cytotoxin from Shiga-t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19933,PHI:12220,UniProt,Q6EZC2,GenBank,AAT68785,,,98NK2,subA,,catalytically inactive mutant,,,,PHI:12221,562,Escherichia coli,,STEC O113:H21,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),J774.1 cell line,,,macrophage,subtilase cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35345462,PubMed,10.1016/j.isci.2022.104050,iScience. 2022 Mar 10;25(4):104050,tsutsuki@kumamoto-u.ac.jp,The murine model of SubAB-producing Citrobacter rodentium demonstrated that SubAB promoted C. rodentium proliferation and worsened symptoms such as intestinal hyperplasia and diarrhea.,H Tsutsuki 2022,2022,2 genes,Tsutsuki-2022-Subtilase cytotoxin from Shiga-t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19934,PHI:12221,UniProt,Q6EZC3,GenBank,AAT68784,,,98NK2,subB,,catalytically inactive mutant,,,,PHI:12220,562,Escherichia coli,,STEC O113:H21,ascending pyelonephritis; urinary tract infection,rodents,10090,Mus musculus (related: house mouse),J774.1 cell line,,,macrophage,subtilase cytotoxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35345462,PubMed,10.1016/j.isci.2022.104050,iScience. 2022 Mar 10;25(4):104050,tsutsuki@kumamoto-u.ac.jp,The murine model of SubAB-producing Citrobacter rodentium demonstrated that SubAB promoted C. rodentium proliferation and worsened symptoms such as intestinal hyperplasia and diarrhea.,H Tsutsuki 2022,2022,2 genes,Tsutsuki-2022-Subtilase cytotoxin from Shiga-t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19935,PHI:12222,UniProt,no data found,GenBank,,,,,Pst_A23,,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,stripe rust (wheat),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; other evidence: transgenic plants,,,YVS,35247281,PubMed,10.1111/pbi.13800,Plant Biotechnol J. 2022 Mar 5,wangxiaojie@nwsuaf.edu.cn,"The transient expression of Pst_A23 suppresses plant basal defence dependent on the Pst_A23 nuclear speckle localization and that this protein plays an important role in virulence, stable silencing of which improves wheat stripe rust resistance.",C Tang 2022,2022,1 gene,Tang-2022-A rust fungus effector directly bind,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19936,PHI:12222,UniProt,no data found,GenBank,,,,,Pst_A23,,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11; cv. Fielder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression; other evidence: transgenic plants,,,YVS,35247281,PubMed,10.1111/pbi.13800,Plant Biotechnol J. 2022 Mar 5,wangxiaojie@nwsuaf.edu.cn,"The transient expression of Pst_A23 suppresses plant basal defence dependent on the Pst_A23 nuclear speckle localization and that this protein plays an important role in virulence, stable silencing of which improves wheat stripe rust resistance.",C Tang 2022,2022,1 gene,Tang-2022-A rust fungus effector directly bind,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19937,PHI:12222,UniProt,no data found,GenBank,,,,,Pst_A23,,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,stripe rust (wheat),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: transgenic plants,,,YVS,35247281,PubMed,10.1111/pbi.13800,Plant Biotechnol J. 2022 Mar 5,wangxiaojie@nwsuaf.edu.cn,"The transient expression of Pst_A23 suppresses plant basal defence dependent on the Pst_A23 nuclear speckle localization and that this protein plays an important role in virulence, stable silencing of which improves wheat stripe rust resistance.",C Tang 2022,2022,1 gene,Tang-2022-A rust fungus effector directly bind,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19938,PHI:12222,UniProt,no data found,GenBank,,,,,Pst_A23,,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11; cv. Fielder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; other evidence: transgenic plants,,,YVS,35247281,PubMed,10.1111/pbi.13800,Plant Biotechnol J. 2022 Mar 5,wangxiaojie@nwsuaf.edu.cn,"The transient expression of Pst_A23 suppresses plant basal defence dependent on the Pst_A23 nuclear speckle localization and that this protein plays an important role in virulence, stable silencing of which improves wheat stripe rust resistance.",C Tang 2022,2022,1 gene,Tang-2022-A rust fungus effector directly bind,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19939,PHI:12222,UniProt,no data found,GenBank,,,,,Pst_A23,,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,stripe rust (wheat),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,35247281,PubMed,10.1111/pbi.13800,Plant Biotechnol J. 2022 Mar 5,wangxiaojie@nwsuaf.edu.cn,"The transient expression of Pst_A23 suppresses plant basal defence dependent on the Pst_A23 nuclear speckle localization and that this protein plays an important role in virulence, stable silencing of which improves wheat stripe rust resistance.",C Tang 2022,2022,1 gene,Tang-2022-A rust fungus effector directly bind,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19940,PHI:12222,UniProt,no data found,GenBank,,,,,Pst_A23,,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,stripe rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11; cv. Fielder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,YVS,35247281,PubMed,10.1111/pbi.13800,Plant Biotechnol J. 2022 Mar 5,wangxiaojie@nwsuaf.edu.cn,"The transient expression of Pst_A23 suppresses plant basal defence dependent on the Pst_A23 nuclear speckle localization and that this protein plays an important role in virulence, stable silencing of which improves wheat stripe rust resistance.",C Tang 2022,2022,1 gene,Tang-2022-A rust fungus effector directly bind,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19941,PHI:12223,UniProt,G4MSW2,GenBank,EHA53816,,,70-15,MoCA1 (MGG_04611),chromosome 2,,,,,,318829,Magnaporthe oryzae,,JJ88,blast,monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,carbonic anhydrase,,,,reduced virulence,,yes,yes,yes,,reduced,,,wild type,no,H2O2; NaHCO3,H2O2: CHEBI:16240; NaHCO3: CHEBI:32139,,,,,gene deletion: full; gene complementation,,,YVS,35250959,PubMed,10.3389/fmicb.2022.845570,Front Microbiol. 2022 Feb 17;13:845570,zhangsh89@syau.edu.cn,The mutant ΔMoCA1 was defective in conidiophore development and pathogenicity.,Y Dang 2022,2022,1 gene,Dang-2022-Contribution of the Mitochondrial Ca,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19942,PHI:12224,UniProt,G4NH41,GenBank,EHA47551,,,70-15,MoPtep1 (MGG_03946),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,monocots,4530,Oryza sativa (related: rice),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,H2O2; MgCl2; sorbitol; Congo red; SDS; CuSO4,H2O2: CHEBI:16240; MgCl2: CHEBI:6636; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414,,,,,gene deletion: full; gene complementation,,,YVS,35269662,PubMed,10.3390/ijms23052515,Int J Mol Sci. 2022 Feb 24;23(5):2515,zhiqiangdo_771@163.com,MoPtep1 was not indispensable for vegetative growth but was required for virulence in M. oryzae.,N Ning 2022,2022,1 gene,Ning-2022-Plant Peroxisome-Targeting Effector,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19943,PHI:12224,UniProt,G4NH41,GenBank,EHA47551,,,70-15,MoPtep1 (MGG_03946),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,H2O2; MgCl2; sorbitol; Congo red; SDS; CuSO4,H2O2: CHEBI:16240; MgCl2: CHEBI:6636; sorbitol: CHEBI:30911; Congo red: CHEBI:34653; SDS: CHEBI:8984; CuSO4: CHEBI:23414,,,,,functional test in host: transient expression,,,YVS,35269662,PubMed,10.3390/ijms23052515,Int J Mol Sci. 2022 Feb 24;23(5):2515,zhiqiangdo_771@163.com,MoPtep1 was not indispensable for vegetative growth but was required for virulence in M. oryzae.,N Ning 2022,2022,1 gene,Ning-2022-Plant Peroxisome-Targeting Effector,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19944,PHI:12225,UniProt,A0A2Z6BW49,GenBank,BBD29223,,,KUB3007,adcA,,,,,,PHI:12226; PHI:12227,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19945,PHI:12226,UniProt,no data found,GenBank,STP97331,,,NCTC370,adcC,,,,,,PHI:12225; PHI:12227,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19946,PHI:12227,UniProt,no data found,GenBank,,,,,adcB,,,,,,PHI:12225; PHI:12226,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19947,PHI:12225,UniProt,A0A2Z6BW49,GenBank,BBD29223,,,KUB3007,adcA,,,,,,PHI:12228,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19948,PHI:12228,UniProt,no data found,GenBank,,,,,adcAII,,,,,,PHI:12225,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,orphan substrate-binding lipoprotein,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19949,PHI:12225,UniProt,A0A2Z6BW49,GenBank,BBD29223,,,KUB3007,adcA,,,,,,PHI:12226; PHI:12227; PHI:12228,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19950,PHI:12226,UniProt,no data found,GenBank,STP97331,,,NCTC370,adcC,,,,,,PHI:12225; PHI:12227; PHI:12228,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19951,PHI:12227,UniProt,no data found,GenBank,,,,,adcB,,,,,,PHI:12225; PHI:12226; PHI:12228,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19952,PHI:12228,UniProt,no data found,GenBank,,,,,adcAII,,,,,,PHI:12225; PHI:12226; PHI:12227,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,orphan substrate-binding lipoprotein,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19953,PHI:12225,UniProt,A0A2Z6BW49,GenBank,BBD29223,,,KUB3007,adcA,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ABC-type transporter,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19954,PHI:12228,UniProt,no data found,GenBank,,,,,adcAII,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,orphan substrate-binding lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19955,PHI:12229,UniProt,no data found,GenBank,CWW59148,,,2842STDY5753961,zur,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19956,PHI:12225,UniProt,A0A2Z6BW49,GenBank,BBD29223,,,KUB3007,adcA,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,peritoneal cavity; spleen,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19957,PHI:12228,UniProt,no data found,GenBank,,,,,adcAII,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,peritoneal cavity; spleen,orphan substrate-binding lipoprotein,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19958,PHI:12225,UniProt,A0A2Z6BW49,GenBank,BBD29223,,,KUB3007,adcA,,,,,,PHI:12226; PHI:12227; PHI:12228,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,peritoneal cavity; spleen,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19959,PHI:12226,UniProt,no data found,GenBank,STP97331,,,NCTC370,adcC,,,,,,PHI:12225; PHI:12227; PHI:12228,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,peritoneal cavity; spleen,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19960,PHI:12227,UniProt,no data found,GenBank,,,,,adcB,,,,,,PHI:12225; PHI:12226; PHI:12228,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,peritoneal cavity; spleen,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19961,PHI:12228,UniProt,no data found,GenBank,,,,,adcAII,,,,,,PHI:12225; PHI:12226; PHI:12227,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,peritoneal cavity; spleen,ABC-type transporter,,,,reduced virulence,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19962,PHI:12228,UniProt,no data found,GenBank,,,,,adcAII,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,kidney,orphan substrate-binding lipoprotein,,,,increased virulence (hypervirulence),,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19963,PHI:12225,UniProt,A0A2Z6BW49,GenBank,BBD29223,,,KUB3007,adcA,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,ABC-type transporter,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19964,PHI:12228,UniProt,no data found,GenBank,,,,,adcAII,,,,,,,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,orphan substrate-binding lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19965,PHI:12225,UniProt,A0A2Z6BW49,GenBank,BBD29223,,,KUB3007,adcA,,,,,,PHI:12226; PHI:12227; PHI:12228,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,ABC-type transporter,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19966,PHI:12226,UniProt,no data found,GenBank,STP97331,,,NCTC370,adcC,,,,,,PHI:12225; PHI:12227; PHI:12228,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,ABC-type transporter,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19967,PHI:12227,UniProt,no data found,GenBank,,,,,adcB,,,,,,PHI:12225; PHI:12226; PHI:12228,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,ABC-type transporter,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19968,PHI:12228,UniProt,no data found,GenBank,,,,,adcAII,,,,,,PHI:12225; PHI:12226; PHI:12227,1351,Enterococcus faecalis,474186,OG1RF,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCr,,,bladder,orphan substrate-binding lipoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; daptomycin; bacitracin; vancomycin,ampicillin: CHEBI:28971; daptomycin: CHEBI:600103; bacitracin: CHEBI:28669; vancomycin: CHEBI:28001,,,,,gene deletion: full; gene complementation,,,YVS,35341449,PubMed,10.1080/21505594.2022.2056965,Virulence. 2022 Dec;13(1):592-608,jlemos@dental.ufl.edu,"Simultaneous inactivation of adcA and adcAII or the entire adcACB operon led to a significant reduction in intracellular Zn under Zn-restricted conditions and heightened sensitivity to Zn-chelating agents including human calprotectin, aberrant cell morphology, and impaired fitness in serum ex vivo.",L N Lam 2022,2022,5 genes,Lam-2022-The AdcACB_AdcAII system is essential,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19969,PHI:12230,UniProt,Q8RJP8,GenBank,AAL78294,,,75-3,xopA,,Xp 91-118::Xer07-xopA,,,,,442694,Xanthomonas perforans,925776,Xp 91-118,bacterial spot,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transconjugation,,,YVS,35336678,PubMed,10.3390/plants11060796,Plants (Basel). 2022 Mar 17;11(6):796,sujan.timilsina@ufl.edu,"The Xer07-xopA, when expressed in X.perforans, did not elicit an HR in tomato leaflets, but significantly reduced bacterial populations. This indicates that xopA and xer3856 genes in combination with an additional factor(s) limit Xer07 in tomato.",Q Fan 2022,2022,2 genes,Fan-2022-Identification of Genes in Xanthomona,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19970,PHI:12231,UniProt,no data found,GenBank,,,,,xer3856,,Xp 91-118::Xer07-xer3856,,,,,442694,Xanthomonas perforans,925776,Xp 91-118,bacterial spot,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,leaf,host-limiting factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,functional test in host: transconjugation,,,YVS,35336678,PubMed,10.3390/plants11060796,Plants (Basel). 2022 Mar 17;11(6):796,sujan.timilsina@ufl.edu,"The Xer07-xopA, when expressed in X.perforans, did not elicit an HR in tomato leaflets, but significantly reduced bacterial populations. This indicates that xopA and xer3856 genes in combination with an additional factor(s) limit Xer07 in tomato.",Q Fan 2022,2022,2 genes,Fan-2022-Identification of Genes in Xanthomona,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19971,PHI:12231,UniProt,no data found,GenBank,,,,,xer3856,,Xer07 Ωxer3856 insertion mutant,,,,,456327,Xanthomonas euvesicatoria,,pv. rosa strain Xer07,bacterial spot,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Bonny Best,,,leaf,host-limiting factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35336678,PubMed,10.3390/plants11060796,Plants (Basel). 2022 Mar 17;11(6):796,sujan.timilsina@ufl.edu,"The Xer07-xopA, when expressed in X.perforans, did not elicit an HR in tomato leaflets, but significantly reduced bacterial populations. This indicates that xopA and xer3856 genes in combination with an additional factor(s) limit Xer07 in tomato.",Q Fan 2022,2022,2 genes,Fan-2022-Identification of Genes in Xanthomona,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19972,PHI:12232,UniProt,Q59638,GenBank,AAC45354,,,PAO,aceF,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,dihydrolipoamide acetyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35336241,PubMed,10.3390/microorganisms10030666,Microorganisms. 2022 Mar 21;10(3):666,pxlay@hotmail.com,The mutations in aceF enhanced a mechanism that promoted the bacterial survival independent of the T3SS.,H Li 2022,2022,2 genes,Li-2022-Dihydrolipoamide Acetyltransferase Ace,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19973,PHI:12233,UniProt,P26993,GenBank,AE004598_1,,,PAO1,exsA,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,HTH-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35336241,PubMed,10.3390/microorganisms10030666,Microorganisms. 2022 Mar 21;10(3):666,pxlay@hotmail.com,The mutations in aceF enhanced a mechanism that promoted the bacterial survival independent of the T3SS.,H Li 2022,2022,2 genes,Li-2022-Dihydrolipoamide Acetyltransferase Ace,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19974,PHI:12232,UniProt,Q59638,GenBank,AAC45354,,,PAO,aceF,,,,,,PHI:12233,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,dihydrolipoamide acetyltransferase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35336241,PubMed,10.3390/microorganisms10030666,Microorganisms. 2022 Mar 21;10(3):666,pxlay@hotmail.com,The mutations in aceF enhanced a mechanism that promoted the bacterial survival independent of the T3SS.,H Li 2022,2022,2 genes,Li-2022-Dihydrolipoamide Acetyltransferase Ace,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19975,PHI:12233,UniProt,P26993,GenBank,AE004598_1,,,PAO1,exsA,,,,,,PHI:12232,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,HTH-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35336241,PubMed,10.3390/microorganisms10030666,Microorganisms. 2022 Mar 21;10(3):666,pxlay@hotmail.com,The mutations in aceF enhanced a mechanism that promoted the bacterial survival independent of the T3SS.,H Li 2022,2022,2 genes,Li-2022-Dihydrolipoamide Acetyltransferase Ace,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19976,PHI:12232,UniProt,Q59638,GenBank,AAC45354,,,PAO,aceF,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,primates,9606,Homo sapiens (related: human),A-549 cell line,,,A-549 cell,dihydrolipoamide acetyltransferase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,YVS,35336241,PubMed,10.3390/microorganisms10030666,Microorganisms. 2022 Mar 21;10(3):666,pxlay@hotmail.com,The mutations in aceF enhanced a mechanism that promoted the bacterial survival independent of the T3SS.,H Li 2022,2022,2 genes,Li-2022-Dihydrolipoamide Acetyltransferase Ace,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19977,PHI:12234,UniProt,A6QKF4,GenBank,BAF68836,,,Newman,icaR,,icaR V176E,,,,,1280,Staphylococcus aureus,1242971,MW2,endocarditis; osteomyelitis; pneumonia; septic shock,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,biofilm operon icaADBC HTH-type negative transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35336176,PubMed,10.3390/microorganisms10030600,Microorganisms. 2022 Mar 10;10(3):600,ilasa@unavarra.es,The icaR isogenic mutant strain exhibited a significantly increased PIA/PNAG production which was unfavourable for bacterial survival in the host.,L Morales-Laverde 2022,2022,1 gene,Morales-Laverde-2022-Experimental Polymorphism,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19978,PHI:12235,UniProt,J4KN88,GenBank,EJP65279,,,ARSEF 2860,SirT2 (BBA_05610),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,class III histone deacetylase,,,,reduced virulence,,,,,,reduced; aberrant,,reduced,reduced,no,NaCl; KCl; sorbitol; hydrogen peroxide; menadione; methyl methanesulfonate; hydroxyurea; Congo red; SDS,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:17924; hydrogen peroxide: CHEBI:16240; menadione: CHEBI:28869; methyl methanesulfonate: CHEBI:25255; hydroxyurea: CHEBI:44423; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,35330238,PubMed,10.3390/jof8030236,J Fungi (Basel). 2022 Feb 27;8(3):236,caiqing@mail.hzau.edu.cn,"Directed gene-knockout of BbSirT2 dramatically reduced conidiation, the ability of the fungus to metabolize a range of carbon and nitrogen sources, and tolerances to oxidative, heat, and UV stress and significantly attenuated virulence in both intrahemocoel injection and topical bioassays using the Greater wax moth (Galleria mellonella) as the insect host.",Q Cai 2022,2022,1 gene,Cai-2022-Contributions of a Histone Deacetylas,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19979,PHI:12236,UniProt,G2XES5,GenBank,EGY18326,,,VdLs.17,VdAda1 (VDAG_08660),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,Spt-Ada-Gcn5 acetyltransferase complex subunit,,,,reduced virulence,,,no,,,reduced; aberrant,,reduced; aberrant,,no,sorbitol; Congo red; SDS,sorbitol: CHEBI:17924; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,35283850,PubMed,10.3389/fmicb.2022.852571,Front Microbiol. 2022 Feb 23;13:852571,zhangdandan@caas.cn,"The deletion of the Ada1 subunit (VdAda1) caused severe defects in the formation of conidia and microsclerotia, and in melanin biosynthesis and virulence.",Q Geng 2022,2022,1 gene,Geng-2022-The Verticillium dahliae Spt-Ada-Gcn,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19980,PHI:12236,UniProt,G2XES5,GenBank,EGY18326,,,VdLs.17,VdAda1 (VDAG_08660),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,Spt-Ada-Gcn5 acetyltransferase complex subunit,,,,reduced virulence,,,no,,,reduced; aberrant,,reduced; aberrant,,no,sorbitol; Congo red; SDS,sorbitol: CHEBI:17924; Congo red: CHEBI:34653; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,YVS,35283850,PubMed,10.3389/fmicb.2022.852571,Front Microbiol. 2022 Feb 23;13:852571,zhangdandan@caas.cn,"The deletion of the Ada1 subunit (VdAda1) caused severe defects in the formation of conidia and microsclerotia, and in melanin biosynthesis and virulence.",Q Geng 2022,2022,1 gene,Geng-2022-The Verticillium dahliae Spt-Ada-Gcn,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19981,PHI:12237,UniProt,Q9I788,GenBank,AE004444_3,,,PAO1,ExoT,,,,,,,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,exoenzyme T,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35277504,PubMed,10.1038/s41467-022-28967-5,Nat Commun. 2022 Mar 11;13(1):1295,Sasha_Shafikhani@rush.edu,ExoT enhanced bacterial fitness in the wounds by dampening the NLRC4 inflammasome.,M F Mohamed 2022,2022,3 genes,Mohamed-2022-CrkII_Abl phosphorylation cascade,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19982,PHI:12238,UniProt,G3XDA1,GenBank,AE004801_6,,,PA103,ExoS,,,,,,,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,secreted exoenzyme S,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35277504,PubMed,10.1038/s41467-022-28967-5,Nat Commun. 2022 Mar 11;13(1):1295,Sasha_Shafikhani@rush.edu,ExoT enhanced bacterial fitness in the wounds by dampening the NLRC4 inflammasome.,M F Mohamed 2022,2022,3 genes,Mohamed-2022-CrkII_Abl phosphorylation cascade,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19983,PHI:12239,UniProt,O34208,GenBank,AAC16023,,,PA103,ExoU,,,,,,,287,Pseudomonas aeruginosa,1081927,PA103,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,type III toxin with phospholipase activity,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,YVS,35277504,PubMed,10.1038/s41467-022-28967-5,Nat Commun. 2022 Mar 11;13(1):1295,Sasha_Shafikhani@rush.edu,ExoT enhanced bacterial fitness in the wounds by dampening the NLRC4 inflammasome.,M F Mohamed 2022,2022,3 genes,Mohamed-2022-CrkII_Abl phosphorylation cascade,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19984,PHI:12240,UniProt,B2HNQ2,GenBank,ACC43857,,,M,esxA,,,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESAT-6 like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19985,PHI:12241,UniProt,P9WNK7,GenBank,CAA56099,,,Erdman,esxA,,ΔesxA::M83IMtb,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,early secretory antigen ESAT-6,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19986,PHI:12241,UniProt,P9WNK7,GenBank,CAA56099,,,Erdman,esxA,,ΔesxA::M93TMtb,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,early secretory antigen ESAT-6,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19987,PHI:12242,UniProt,A0A2Z5YNV9,GenBank,BBC68980,,,ATCC 927,eccA1,,Mm-eccA1::Tn,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,even-toed ungulates,9940,Ovis aries (related: sheep),,,,erythrocyte,ESX-1 secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19988,PHI:12240,UniProt,B2HNQ2,GenBank,ACC43857,,,M,esxA,,,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,ESAT-6 like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19989,PHI:12241,UniProt,P9WNK7,GenBank,CAA56099,,,Erdman,esxA,,ΔesxA::M83IMtb,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,early secretory antigen ESAT-6,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19990,PHI:12241,UniProt,P9WNK7,GenBank,CAA56099,,,Erdman,esxA,,ΔesxA::M93TMtb,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,early secretory antigen ESAT-6,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19991,PHI:12242,UniProt,A0A2Z5YNV9,GenBank,BBC68980,,,ATCC 927,eccA1,,Mm-eccA1::Tn,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,ESX-1 secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19992,PHI:12240,UniProt,B2HNQ2,GenBank,ACC43857,,,M,esxA,,,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,ESAT-6 like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19993,PHI:12241,UniProt,P9WNK7,GenBank,CAA56099,,,Erdman,esxA,,ΔesxA::M83IMtb,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,early secretory antigen ESAT-6,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19994,PHI:12241,UniProt,P9WNK7,GenBank,CAA56099,,,Erdman,esxA,,ΔesxA::M93TMtb,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,early secretory antigen ESAT-6,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19995,PHI:12242,UniProt,A0A2Z5YNV9,GenBank,BBC68980,,,ATCC 927,eccA1,,Mm-eccA1::Tn,,,,PHI:8960,1781,Mycobacterium marinum,216594,M,opportunistic infection,bony fishes,7955,Danio rerio (related: zebrafish),,,,,ESX-1 secretion system protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,YVS,35271388,PubMed,10.1073/pnas.2122161119,Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2122161119,lalitar@mrc-lmb.ac.uk,ESAT-6 C-terminal point mutants was required for phagosomal membrane damage and virulence.,M M Osman 2022,2022,3 genes,Osman-2022-The C terminus of the mycobacterium,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19996,PHI:12243,,no data found,GenBank,AGS66382,,,CA382,gpsA,,,,,,,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,ear; talus; bladder,NAD(P)H-dependent glycerol-3-phosphate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35255112,PubMed,10.1371/journal.ppat.1010385,PLoS Pathog. 2022 Mar 7;18(3):e1010385,dan.drecktrah@mso.umt.edu,"A glpD deletion restored the wild-type phenotype to the pleiotropic gpsA mutant, including murine infectivity by needle inoculation athigh doses, survival under nutrient stress, morphological changes and the metabolic imbalance of NADH and glycerol-3-phosphate.",D Drecktrah 2022,2022,2 genes,Drecktrah-2022-The glycerol-3-phosphate dehydr,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19997,PHI:12244,UniProt,no data found,GenBank,,,,,glpD,,,,,,,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,ear; talus; bladder,glycerol-3-phosphate dehydrogenase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35255112,PubMed,10.1371/journal.ppat.1010385,PLoS Pathog. 2022 Mar 7;18(3):e1010385,dan.drecktrah@mso.umt.edu,"A glpD deletion restored the wild-type phenotype to the pleiotropic gpsA mutant, including murine infectivity by needle inoculation athigh doses, survival under nutrient stress, morphological changes and the metabolic imbalance of NADH and glycerol-3-phosphate.",D Drecktrah 2022,2022,2 genes,Drecktrah-2022-The glycerol-3-phosphate dehydr,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19998,PHI:12243,,no data found,GenBank,AGS66382,,,CA382,gpsA,,,,,,PHI:12244,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,ear; talus; bladder,NAD(P)H-dependent glycerol-3-phosphate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35255112,PubMed,10.1371/journal.ppat.1010385,PLoS Pathog. 2022 Mar 7;18(3):e1010385,dan.drecktrah@mso.umt.edu,"A glpD deletion restored the wild-type phenotype to the pleiotropic gpsA mutant, including murine infectivity by needle inoculation athigh doses, survival under nutrient stress, morphological changes and the metabolic imbalance of NADH and glycerol-3-phosphate.",D Drecktrah 2022,2022,2 genes,Drecktrah-2022-The glycerol-3-phosphate dehydr,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 19999,PHI:12244,UniProt,no data found,GenBank,,,,,glpD,,,,,,PHI:12243,139,Borreliella burgdorferi,,B31 5A4,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,ear; talus; bladder,glycerol-3-phosphate dehydrogenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35255112,PubMed,10.1371/journal.ppat.1010385,PLoS Pathog. 2022 Mar 7;18(3):e1010385,dan.drecktrah@mso.umt.edu,"A glpD deletion restored the wild-type phenotype to the pleiotropic gpsA mutant, including murine infectivity by needle inoculation athigh doses, survival under nutrient stress, morphological changes and the metabolic imbalance of NADH and glycerol-3-phosphate.",D Drecktrah 2022,2022,2 genes,Drecktrah-2022-The glycerol-3-phosphate dehydr,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20000,PHI:12245,UniProt,G1XR26,GenBank,EGX44297,,,ATCC 24927,AoArc1 (AOL_s00193g25),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,arrestin,,,,reduced virulence,,,,,,wild type,,aberrant,,no,H2O2; sorbitol; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; sorbitol: CHEBI:17924; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,YVS,35252023,PubMed,10.3389/fcimb.2022.754333,Front Cell Infect Microbiol. 2022 Feb 16;12:754333,xinwang2@ynu.edu.cn,The capacity of trap device formation against nematodes and ammonia was impaired due to AoArc deletions.,L Zhou 2022,2022,7 genes,Zhou-2022-Arrestin-Coding Genes Regulate Endoc,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20001,PHI:12246,UniProt,G1XR75,GenBank,EGX44346,,,ATCC 24927,AoArc2 (AOL_s00193g74),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,arrestin,,,,reduced virulence,,,,,,reduced,,aberrant,,no,H2O2; sorbitol; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; sorbitol: CHEBI:17924; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,YVS,35252023,PubMed,10.3389/fcimb.2022.754333,Front Cell Infect Microbiol. 2022 Feb 16;12:754333,xinwang2@ynu.edu.cn,The capacity of trap device formation against nematodes and ammonia was impaired due to AoArc deletions.,L Zhou 2022,2022,7 genes,Zhou-2022-Arrestin-Coding Genes Regulate Endoc,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20002,PHI:12247,UniProt,G1X3H7,GenBank,EGX52461,,,ATCC 24927,AoArc5 (AOL_s00043g250),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,arrestin,,,,reduced virulence,,,,,,reduced,,aberrant,,no,H2O2; sorbitol; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; sorbitol: CHEBI:17924; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,YVS,35252023,PubMed,10.3389/fcimb.2022.754333,Front Cell Infect Microbiol. 2022 Feb 16;12:754333,xinwang2@ynu.edu.cn,The capacity of trap device formation against nematodes and ammonia was impaired due to AoArc deletions.,L Zhou 2022,2022,7 genes,Zhou-2022-Arrestin-Coding Genes Regulate Endoc,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20003,PHI:12248,UniProt,G1XM14,GenBank,EGX45856,,,ATCC 24927,AoArc6 (AOL_s00117g61),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,arrestin,,,,reduced virulence,,,,,,reduced,,aberrant,,no,H2O2; sorbitol; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; sorbitol: CHEBI:17924; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,YVS,35252023,PubMed,10.3389/fcimb.2022.754333,Front Cell Infect Microbiol. 2022 Feb 16;12:754333,xinwang2@ynu.edu.cn,The capacity of trap device formation against nematodes and ammonia was impaired due to AoArc deletions.,L Zhou 2022,2022,7 genes,Zhou-2022-Arrestin-Coding Genes Regulate Endoc,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20004,PHI:12249,UniProt,G1X638,GenBank,EGX51262,,,ATCC 24927,AoArc7 (AOL_s00054g332),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,arrestin,,,,reduced virulence,,,,,,reduced,,aberrant,,no,H2O2; sorbitol; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; sorbitol: CHEBI:17924; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,YVS,35252023,PubMed,10.3389/fcimb.2022.754333,Front Cell Infect Microbiol. 2022 Feb 16;12:754333,xinwang2@ynu.edu.cn,The capacity of trap device formation against nematodes and ammonia was impaired due to AoArc deletions.,L Zhou 2022,2022,7 genes,Zhou-2022-Arrestin-Coding Genes Regulate Endoc,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20005,PHI:12250,UniProt,G1XAL6,GenBank,EGX49790,,,ATCC 24927,AoArc10 (AOL_s00076g674),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,arrestin,,,,reduced virulence,,,,,,wild type,,,,no,H2O2; sorbitol; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; sorbitol: CHEBI:17924; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,YVS,35252023,PubMed,10.3389/fcimb.2022.754333,Front Cell Infect Microbiol. 2022 Feb 16;12:754333,xinwang2@ynu.edu.cn,The capacity of trap device formation against nematodes and ammonia was impaired due to AoArc deletions.,L Zhou 2022,2022,7 genes,Zhou-2022-Arrestin-Coding Genes Regulate Endoc,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20006,PHI:12251,UniProt,G1WYI5,GenBank,EGX54312,,,ATCC 24927,AoArc12 (AOL_s00004g345),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,arrestin,,,,reduced virulence,,,,,,wild type,,,,no,H2O2; sorbitol; sodium dodecyl sulfate (SDS),H2O2: CHEBI:16240; sorbitol: CHEBI:17924; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,YVS,35252023,PubMed,10.3389/fcimb.2022.754333,Front Cell Infect Microbiol. 2022 Feb 16;12:754333,xinwang2@ynu.edu.cn,The capacity of trap device formation against nematodes and ammonia was impaired due to AoArc deletions.,L Zhou 2022,2022,7 genes,Zhou-2022-Arrestin-Coding Genes Regulate Endoc,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20007,PHI:12252,UniProt,H3RHG9,GenBank,ARF52028,,,DC283,nsrR,,,,,,,66269,Pantoea stewartii,66271,subsp. stewartii,Stewart's wilt; leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Jubilee; cv. B73,,,seed,DNA-binding transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35237242,PubMed,10.3389/fmicb.2021.806504,Front Microbiol. 2022 Feb 14;12:806504,ams@vt.edu,Single infections of each deletion strain into the xylem of corn seedlings determined that Lrp played a significant role in P. stewartii virulence.,H P Bartholomew 2022,2022,5 genes,Bartholomew-2021-The Transcription Factor Lrp,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20008,PHI:12253,UniProt,H3RGK7,GenBank,ARF49198,,,DC283,iscR,,,,,,,66269,Pantoea stewartii,66271,subsp. stewartii,Stewart's wilt; leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Jubilee; cv. B73,,,seed,Fe-S cluster assembly transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35237242,PubMed,10.3389/fmicb.2021.806504,Front Microbiol. 2022 Feb 14;12:806504,ams@vt.edu,Single infections of each deletion strain into the xylem of corn seedlings determined that Lrp played a significant role in P. stewartii virulence.,H P Bartholomew 2022,2022,5 genes,Bartholomew-2021-The Transcription Factor Lrp,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20009,PHI:12254,UniProt,H3RDZ6,GenBank,ARF49911,,,DC283,nac,,,,,,,66269,Pantoea stewartii,66271,subsp. stewartii,Stewart's wilt; leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Jubilee; cv. B73,,,seed,nitrogen assimilation transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35237242,PubMed,10.3389/fmicb.2021.806504,Front Microbiol. 2022 Feb 14;12:806504,ams@vt.edu,Single infections of each deletion strain into the xylem of corn seedlings determined that Lrp played a significant role in P. stewartii virulence.,H P Bartholomew 2022,2022,5 genes,Bartholomew-2021-The Transcription Factor Lrp,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20010,PHI:12255,UniProt,H3RDJ5,GenBank,ARF49975,,,DC283,rcsA,,,,,,,66269,Pantoea stewartii,66271,subsp. stewartii,Stewart's wilt; leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Jubilee; cv. B73,,,seed,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35237242,PubMed,10.3389/fmicb.2021.806504,Front Microbiol. 2022 Feb 14;12:806504,ams@vt.edu,Single infections of each deletion strain into the xylem of corn seedlings determined that Lrp played a significant role in P. stewartii virulence.,H P Bartholomew 2022,2022,5 genes,Bartholomew-2021-The Transcription Factor Lrp,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20011,PHI:12256,UniProt,H3RB93,GenBank,ARF49545,,,DC283,lrp,,,,,,,66269,Pantoea stewartii,66271,subsp. stewartii,Stewart's wilt; leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Jubilee; cv. B73,,,seed,leucine-binding DNA-binding transcriptional dual regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,YVS,35237242,PubMed,10.3389/fmicb.2021.806504,Front Microbiol. 2022 Feb 14;12:806504,ams@vt.edu,Single infections of each deletion strain into the xylem of corn seedlings determined that Lrp played a significant role in P. stewartii virulence.,H P Bartholomew 2022,2022,5 genes,Bartholomew-2021-The Transcription Factor Lrp,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20012,PHI:12257,UniProt,E9F004,GenBank,EFY98464,,,ARSEF 23,EFY98464.1 (MrGPA2),,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,guanine nucleotide-binding protein alpha-2 subunit,,,,unaffected pathogenicity,,no,,,,wild type,,wild type,wild type,no,H2O2; NaCl; Congo red,H2O2: CHEBI:16240; NaCl: CHEBI:26710; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35205884,PubMed,10.3390/jof8020132,J Fungi (Basel). 2022 Jan 28;8(2):132,tongyoumin@stu.ahau.edu.cn,MrGpa2 and MrGpa4 had no effect on appressorium formation,Y Tong 2022,2022,2 genes,Tong-2022-Role of Two G-Protein α Subunits in,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20013,PHI:12258,UniProt,E9EY89,GenBank,EFZ00060,,,ARSEF 23,EFZ00060.2 (MrGPA4),,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"guanine nucleotide binding protein (G-protein), alpha subunit",,,,unaffected pathogenicity,,no,,,,wild type,,wild type,wild type,no,H2O2; NaCl; Congo red,H2O2: CHEBI:16240; NaCl: CHEBI:26710; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35205884,PubMed,10.3390/jof8020132,J Fungi (Basel). 2022 Jan 28;8(2):132,tongyoumin@stu.ahau.edu.cn,MrGpa2 and MrGpa4 had no effect on appressorium formation,Y Tong 2022,2022,2 genes,Tong-2022-Role of Two G-Protein α Subunits in,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20014,PHI:12257,UniProt,E9F004,GenBank,EFY98464,,,ARSEF 23,EFY98464.1 (MrGPA2),,,,,,PHI:12258,568076,Metarhizium robertsii,655844,ARSEF 23,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,guanine nucleotide-binding protein alpha-2 subunit,,,,reduced virulence,,no,,,,wild type,,reduced,wild type,no,H2O2; NaCl; Congo red,H2O2: CHEBI:16240; NaCl: CHEBI:26710; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35205884,PubMed,10.3390/jof8020132,J Fungi (Basel). 2022 Jan 28;8(2):132,tongyoumin@stu.ahau.edu.cn,MrGpa2 and MrGpa4 had no effect on appressorium formation,Y Tong 2022,2022,2 genes,Tong-2022-Role of Two G-Protein α Subunits in,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20015,PHI:12258,UniProt,E9EY89,GenBank,EFZ00060,,,ARSEF 23,EFZ00060.2 (MrGPA4),,,,,,PHI:12257,568076,Metarhizium robertsii,655844,ARSEF 23,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"guanine nucleotide binding protein (G-protein), alpha subunit",,,,reduced virulence,,,,,,wild type,,reduced,wild type,no,H2O2; NaCl; Congo red,H2O2: CHEBI:16240; NaCl: CHEBI:26710; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35205884,PubMed,10.3390/jof8020132,J Fungi (Basel). 2022 Jan 28;8(2):132,tongyoumin@stu.ahau.edu.cn,MrGpa2 and MrGpa4 had no effect on appressorium formation,Y Tong 2022,2022,2 genes,Tong-2022-Role of Two G-Protein α Subunits in,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20016,PHI:12259,UniProt,E9DXX9,GenBank,EFY91592,,,CQMa 102,MaSom1 (GenBank accession No. MAC_02477) (OE-4),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,hemolymph,SOM1 protein,,,cAMP/PKA pathway,increased virulence (hypervirulence),,no,,,,wild type,,increased,defective,no,calcofluor white; congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: overexpression,,,NN,35205860,PubMed,10.3390/jof8020105,J Fungi (Basel). 2022 Jan 21;8(2):105,yuxianxia@cqu.edu.cn,MaSom1 significantly increased the fungal tolerances to heat shock and UV-B irradiation in M. acridum,Y Du 2022,2022,1 gene,Du-2022-Enhancing the Biocontrol Potential of,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20017,PHI:12260,UniProt,E9DXX9,GenBank,EFY91592,,,CQMa 102,MaSom1 (GenBank accession No. MAC_02477) (OE-34),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,hemolymph,SOM1 protein,,,cAMP/PKA pathway,increased virulence (hypervirulence),,no,,,,wild type,,increased,defective,no,calcofluor white; congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: overexpression,,,NN,35205860,PubMed,10.3390/jof8020105,J Fungi (Basel). 2022 Jan 21;8(2):105,yuxianxia@cqu.edu.cn,MaSom1 significantly increased the fungal tolerances to heat shock and UV-B irradiation in M. acridum,Y Du 2022,2022,1 gene,Du-2022-Enhancing the Biocontrol Potential of,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20018,PHI:12261,UniProt,E9DXX9,GenBank,EFY91592,,,CQMa 102,MaSom1 (GenBank accession No. MAC_02477) (OE-55),,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,hemolymph,SOM1 protein,,,cAMP/PKA pathway,increased virulence (hypervirulence),,no,,,,wild type,,increased,defective,no,calcofluor white; congo red,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: overexpression,,,NN,35205860,PubMed,10.3390/jof8020105,J Fungi (Basel). 2022 Jan 21;8(2):105,yuxianxia@cqu.edu.cn,MaSom1 significantly increased the fungal tolerances to heat shock and UV-B irradiation in M. acridum,Y Du 2022,2022,1 gene,Du-2022-Enhancing the Biocontrol Potential of,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20019,PHI:12262,UniProt,B4EQ58,GenBank,CAR57224,,,J2315,BCAS0292,chromosome 3,,,"HctB, a histone H1-like protein; BCAM1012; SecA",GenBank: AAA23130; GenBank: CAR54869; GenBank: CAR53776,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,DNA-mimic protein,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,polymyxin B; meropenem,polymyxin B: CHEBI:8309; meropenem: CHEBI:43968,,,,,gene mutation; gene complementation,,,NN,35212475,PubMed,10.1002/mbo3.1264,Microbiologyopen. 2022 Feb;11(1):e1264,siobhan.mcclean@ucd.ie,ΔBCAS0292 mutant cells showed significantly increased biofilm formation,R Dennehy 2022,2022,1 gene,Dennehy-2022-Protein with negative surface cha,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20020,PHI:12263,,no data found,,,,,,motam1,,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,tryptophan aminotransferase,,,IAA biosynthesis pathway; YUCCA pathway,reduced virulence,,,,,reduced blast lesions,wild type,,defective,,no,tryptophan; yucasin,tryptophan: CHEBI:27897; yucasin: CAS:26028-65-9,,,,,gene mutation,,,NN,35205962,PubMed,10.3390/jof8020208,J Fungi (Basel). 2022 Feb 21;8(2):208,lihongd@stu.scau.edu.cn,Fungus derived IAA plays major role in regulating M. oryzae growth and pathogenicity,L Dong 2022,2022,6 genes,Dong-2022-Identification and Characterization,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20021,PHI:12264,,no data found,,,,,,moaro8,,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,aromatic/aminoadipate aminotransferase 1,,,IAA biosynthesis pathway; YUCCA pathway,unaffected pathogenicity,,,,,typical blast lesions,wild type,,wild type,,no,tryptophan; yucasin,tryptophan: CHEBI:27897; yucasin: CAS:26028-65-9,,,,,gene mutation,,,NN,35205962,PubMed,10.3390/jof8020208,J Fungi (Basel). 2022 Feb 21;8(2):208,lihongd@stu.scau.edu.cn,Fungus derived IAA plays major role in regulating M. oryzae growth and pathogenicity,L Dong 2022,2022,6 genes,Dong-2022-Identification and Characterization,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20022,PHI:12265,,no data found,,,,,,moaro9,,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,aromatic aminotransferase II,,,IAA biosynthesis pathway; YUCCA pathway,unaffected pathogenicity,,,,,typical blast lesions,wild type,,wild type,,no,tryptophan; yucasin,tryptophan: CHEBI:27897; yucasin: CAS:26028-65-9,,,,,gene mutation,,,NN,35205962,PubMed,10.3390/jof8020208,J Fungi (Basel). 2022 Feb 21;8(2):208,lihongd@stu.scau.edu.cn,Fungus derived IAA plays major role in regulating M. oryzae growth and pathogenicity,L Dong 2022,2022,6 genes,Dong-2022-Identification and Characterization,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20023,PHI:12265,,no data found,,,,,,moaro9,,,,,,PHI:12264,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,aromatic aminotransferase II,,,IAA biosynthesis pathway; YUCCA pathway,unaffected pathogenicity,,,,,typical blast lesions,wild type,,wild type,,no,tryptophan; yucasin,tryptophan: CHEBI:27897; yucasin: CAS:26028-65-9,,,,,gene mutation,,,NN,35205962,PubMed,10.3390/jof8020208,J Fungi (Basel). 2022 Feb 21;8(2):208,lihongd@stu.scau.edu.cn,Fungus derived IAA plays major role in regulating M. oryzae growth and pathogenicity,L Dong 2022,2022,6 genes,Dong-2022-Identification and Characterization,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20024,PHI:12264,,no data found,,,,,,moaro8,,,,,,PHI:12265,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,aromatic/aminoadipate aminotransferase 1,,,IAA biosynthesis pathway; YUCCA pathway,unaffected pathogenicity,,,,,typical blast lesions,wild type,,wild type,,no,tryptophan; yucasin,tryptophan: CHEBI:27897; yucasin: CAS:26028-65-9,,,,,gene mutation,,,NN,35205962,PubMed,10.3390/jof8020208,J Fungi (Basel). 2022 Feb 21;8(2):208,lihongd@stu.scau.edu.cn,Fungus derived IAA plays major role in regulating M. oryzae growth and pathogenicity,L Dong 2022,2022,6 genes,Dong-2022-Identification and Characterization,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20025,PHI:12266,,no data found,,,,,,moipd1,,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,indole-3-pyruvate decarboxylase,,,IAA biosynthesis pathway; YUCCA pathway,loss of pathogenicity,,,,,unable to cause blast disease lesions,aberrant,,defective,,no,tryptophan; yucasin,tryptophan: CHEBI:27897; yucasin: CAS:26028-65-9,,,,,gene mutation,,,NN,35205962,PubMed,10.3390/jof8020208,J Fungi (Basel). 2022 Feb 21;8(2):208,lihongd@stu.scau.edu.cn,Fungus derived IAA plays major role in regulating M. oryzae growth and pathogenicity,L Dong 2022,2022,6 genes,Dong-2022-Identification and Characterization,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20026,PHI:12267,,no data found,,,,,,moiad1,,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,indole-3-acetaldehyde dehydrogenase,,,IAA biosynthesis pathway; YUCCA pathway,unaffected pathogenicity,,,,,typical blast lesions,wild type,,aberrant,,no,tryptophan; yucasin,tryptophan: CHEBI:27897; yucasin: CAS:26028-65-9,,,,,gene mutation,,,NN,35205962,PubMed,10.3390/jof8020208,J Fungi (Basel). 2022 Feb 21;8(2):208,lihongd@stu.scau.edu.cn,Fungus derived IAA plays major role in regulating M. oryzae growth and pathogenicity,L Dong 2022,2022,6 genes,Dong-2022-Identification and Characterization,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20027,PHI:12268,,no data found,,,,,,moiad2,,,,,,,318829,Magnaporthe oryzae,1348879,B157,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,indole-3-acetaldehyde dehydrogenase,,,IAA biosynthesis pathway; YUCCA pathway,unaffected pathogenicity,,,,,typical blast lesions,wild type,,aberrant,,no,tryptophan; yucasin,tryptophan: CHEBI:27897; yucasin: CAS:26028-65-9,,,,,gene mutation,,,NN,35205962,PubMed,10.3390/jof8020208,J Fungi (Basel). 2022 Feb 21;8(2):208,lihongd@stu.scau.edu.cn,Fungus derived IAA plays major role in regulating M. oryzae growth and pathogenicity,L Dong 2022,2022,6 genes,Dong-2022-Identification and Characterization,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20028,PHI:12269,UniProt,A0A5C7CFY5,GenBank,TXE36820,,,S16,FliR,,,,,,,615,Serratia marcescens,,Db10,opportunistic infection,flies,7227,Drosophila melanogaster (related: fruit fly),eater−/−,,,,flagellar biosynthetic protein FliR,,,,reduced virulence,,,yes,,,,,,,no,,,,,,,gene disruption; gene complementation,,,NN,35197500,PubMed,10.1038/s41598-022-06780-w,Sci Rep. 2022 Feb 23;12(1):3068,D.Ferrandon@ibmc-cnrs.unistra.fr,Serratia marcescens infection is independent of flagellum,B Sina Rahme 2022,2022,2 genes,Sina Rahme-2022-The fliR gene contributes to t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20029,PHI:12270,UniProt,A0A5C7CFY5,GenBank,TXE36820,,,S16,FliR,,,,,,,615,Serratia marcescens,,RM66262,opportunistic infection,flies,7227,Drosophila melanogaster (related: fruit fly),eater−/−,,,,flagellar biosynthetic protein FliR,,,,reduced virulence,,,yes,,,,,,,no,,,,,,,gene disruption; gene complementation,,,NN,35197500,PubMed,10.1038/s41598-022-06780-w,Sci Rep. 2022 Feb 23;12(1):3068,D.Ferrandon@ibmc-cnrs.unistra.fr,Serratia marcescens infection is independent of flagellum,B Sina Rahme 2022,2022,2 genes,Sina Rahme-2022-The fliR gene contributes to t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20030,PHI:12271,UniProt,O85806,GenBank,AAC27633,,,CH-1,FlhD,,,,,,,615,Serratia marcescens,,Db10,opportunistic infection,flies,7227,Drosophila melanogaster (related: fruit fly),eater−/−,,,,flagellar transcriptional regulator FlhD,,,,unaffected pathogenicity,,,yes,,,,,,,no,,,,,,,gene disruption,,,NN,35197500,PubMed,10.1038/s41598-022-06780-w,Sci Rep. 2022 Feb 23;12(1):3068,D.Ferrandon@ibmc-cnrs.unistra.fr,Serratia marcescens infection is independent of flagellum,B Sina Rahme 2022,2022,2 genes,Sina Rahme-2022-The fliR gene contributes to t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20031,PHI:12272,UniProt,O85806,GenBank,AAC27633,,,CH-1,FlhD,,,,,,,615,Serratia marcescens,,RM66262,opportunistic infection,flies,7227,Drosophila melanogaster (related: fruit fly),eater−/−,,,,flagellar transcriptional regulator FlhD,,,,unaffected pathogenicity,,,yes,,,,,,,no,,,,,,,gene disruption,,,NN,35197500,PubMed,10.1038/s41598-022-06780-w,Sci Rep. 2022 Feb 23;12(1):3068,D.Ferrandon@ibmc-cnrs.unistra.fr,Serratia marcescens infection is independent of flagellum,B Sina Rahme 2022,2022,2 genes,Sina Rahme-2022-The fliR gene contributes to t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20032,PHI:12273,UniProt,A0A5C7CFY5,GenBank,TXE36820,,,S16,FliR,,,,,,,615,Serratia marcescens,,Db10,opportunistic infection,flies,7227,Drosophila melanogaster (related: fruit fly),wA5001,,,,flagellar biosynthetic protein FliR,,,,reduced virulence,,,yes,,,,,,,no,,,,,,,gene disruption; gene complementation,,,NN,35197500,PubMed,10.1038/s41598-022-06780-w,Sci Rep. 2022 Feb 23;12(1):3068,D.Ferrandon@ibmc-cnrs.unistra.fr,Serratia marcescens infection is independent of flagellum,B Sina Rahme 2022,2022,2 genes,Sina Rahme-2022-The fliR gene contributes to t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20033,PHI:12274,UniProt,A0A5C7CFY5,GenBank,TXE36820,,,S16,FliR,,,,,,,615,Serratia marcescens,,RM66262,opportunistic infection,flies,7227,Drosophila melanogaster (related: fruit fly),wA5001,,,,flagellar biosynthetic protein FliR,,,,reduced virulence,,,yes,,,,,,,no,,,,,,,gene disruption; gene complementation,,,NN,35197500,PubMed,10.1038/s41598-022-06780-w,Sci Rep. 2022 Feb 23;12(1):3068,D.Ferrandon@ibmc-cnrs.unistra.fr,Serratia marcescens infection is independent of flagellum,B Sina Rahme 2022,2022,2 genes,Sina Rahme-2022-The fliR gene contributes to t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20034,PHI:12275,UniProt,O85806,GenBank,AAC27633,,,CH-1,FlhD,,,,,,,615,Serratia marcescens,,Db10,opportunistic infection,flies,7227,Drosophila melanogaster (related: fruit fly),wA5001,,,,flagellar transcriptional regulator FlhD,,,,unaffected pathogenicity,,,yes,,,,,,,no,,,,,,,gene disruption,,,NN,35197500,PubMed,10.1038/s41598-022-06780-w,Sci Rep. 2022 Feb 23;12(1):3068,D.Ferrandon@ibmc-cnrs.unistra.fr,Serratia marcescens infection is independent of flagellum,B Sina Rahme 2022,2022,2 genes,Sina Rahme-2022-The fliR gene contributes to t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20035,PHI:12276,UniProt,O85806,GenBank,AAC27633,,,CH-1,FlhD,,,,,,,615,Serratia marcescens,,RM66262,opportunistic infection,flies,7227,Drosophila melanogaster (related: fruit fly),wA5001,,,,flagellar transcriptional regulator FlhD,,,,unaffected pathogenicity,,,yes,,,,,,,no,,,,,,,gene disruption,,,NN,35197500,PubMed,10.1038/s41598-022-06780-w,Sci Rep. 2022 Feb 23;12(1):3068,D.Ferrandon@ibmc-cnrs.unistra.fr,Serratia marcescens infection is independent of flagellum,B Sina Rahme 2022,2022,2 genes,Sina Rahme-2022-The fliR gene contributes to t,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20036,PHI:12277,UniProt,A0A0P1KYY9,GenBank,CUS27868,,,CBS252.59,CgEP1,,Ko-14,,,,,31870,Colletotrichum graminicola,,M1.001 BH,anthracnose (maize); leaf blight,monocots,4577,Zea mays (related: maize),Mo940 line,,,leaf,host-nuclear effector,,,,loss of pathogenicity,,yes,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,26554735,PubMed,10.1094/MPMI-09-15-0209-R,Mol Plant Microbe Interact. 2016 Feb;29(2):83-95,ssukno@usal.es,DNA-binding proteins that target host genomic DNA and may be involved in regulatory processes preventing host-defensive responses against plant pathogens.,W A Vargas 2016,2016,1 gene,mpmi-09-15-0209-r,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20037,PHI:12278,,no data found,,,,,,MoPAH1 (M21),,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,phosphatidate phosphatase,,,,loss of pathogenicity,,yes,,,no visible lesion,defective,,reduced,,no,Congo red; NaCl; sorbitol,Congo red: CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene mutation; gene complementation,,,NN,35191164,PubMed,10.1111/mpp.13193,Mol Plant Pathol. 2022 May;23(5):720-732,Qiang.Li@mail.hzau.edu.cn,MoPAH1 widely alters the lipid metabolism in M. oryzae.,J Zhao 2022,2022,1 gene,Zhao-2022-The MoPah1 phosphatidate phosphatase,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20038,PHI:12279,,no data found,,,,,,MoPAH1 (M21),,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,phosphatidate phosphatase,,,,loss of pathogenicity,,yes,,,,defective,,reduced,,no,Congo red; NaCl; sorbitol,Congo red: CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene mutation; gene complementation,,,NN,35191164,PubMed,10.1111/mpp.13193,Mol Plant Pathol. 2022 May;23(5):720-732,Qiang.Li@mail.hzau.edu.cn,MoPAH1 widely alters the lipid metabolism in M. oryzae.,J Zhao 2022,2022,1 gene,Zhao-2022-The MoPah1 phosphatidate phosphatase,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20039,PHI:122980,UniProt,Q9HY15,GenBank,AE004781_7,,,PAO1,PA3611,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,bronchial fibrosis,primates,9606,Homo sapiens (related: human),,,,16-HBE14o cell,protein PA3611,,,p38/NF-kB pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197937,PubMed,10.3389/fmicb.2021.763749,Front Microbiol. 2022 Feb 7;12:763749,fenggz@njmu.edu.cn,PA3611 acts as a crucial virulence factor in bronchial epithelial cell EMT and is a potential target forthe clinical treatment of bronchial EMT and fibrosis caused by chronic PA infection,L Shu 2022,2022,1 gene,Shu-2021-The Pseudomonas aeruginosa Secreted P,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20040,PHI:122981,UniProt,Q9HY15,GenBank,AE004781_7,,,PAO1,PA3611,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,bronchial fibrosis,rodents,10114,Rattus (related: rat),RTE cell line,,,bronchial epithelial cell line,protein PA3611,,,p38/NF-kB pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197937,PubMed,10.3389/fmicb.2021.763749,Front Microbiol. 2022 Feb 7;12:763749,fenggz@njmu.edu.cn,PA3611 acts as a crucial virulence factor in bronchial epithelial cell EMT and is a potential target forthe clinical treatment of bronchial EMT and fibrosis caused by chronic PA infection,L Shu 2022,2022,1 gene,Shu-2021-The Pseudomonas aeruginosa Secreted P,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20041,PHI:122982,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20042,PHI:122983,UniProt,I1S480,GenBank,CEF71829,,,PH-1,osp25 (FGSG_11647),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20043,PHI:122984,UniProt,I1S9D3,GenBank,CEF76225,,,PH-1,osp44 (FGSG_13464),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20044,PHI:122985,UniProt,I1RGP1,GenBank,CEF77607,,,PH-1,osp4 (FGSG_02914),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20045,PHI:122986,UniProt,I1RLG7,GenBank,CEF85846,,,PH-1,osp8 (FGSG_04766),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20046,PHI:122987,UniProt,I1RTA2,GenBank,CEF83215,,,PH-1,osp13 (FGSG_07403),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20047,PHI:122988,UniProt,I1RX58,GenBank,CEF77376,,,PH-1,osp19 (FGSG_08908),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20048,PHI:122989,UniProt,I1S5C7,GenBank,CEF74187,,,PH-1,osp29 (FGSG_12045),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20049,PHI:122990,UniProt,I1S799,GenBank,CEF86781,,,PH-1,osp33 (FGSG_12722),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20050,PHI:122991,UniProt,I1S7V7,GenBank,CEF85474,,,PH-1,osp36 (FGSG_12932),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20051,PHI:122992,UniProt,I1S8D7,GenBank,CEF84789,,,PH-1,osp40 (FGSG_13115),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20052,PHI:122993,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhoumai 36,,,spike,orphan secreted protein,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20053,PHI:122994,UniProt,I1S480,GenBank,CEF71829,,,PH-1,osp25 (FGSG_11647),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhoumai 36,,,spike,orphan secreted protein,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20054,PHI:122995,UniProt,I1S9D3,GenBank,CEF76225,,,PH-1,osp44 (FGSG_13464),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhoumai 36,,,spike,orphan secreted protein,,,,reduced virulence,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20055,PHI:122996,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,Cysteine changed to alanine at 94th position,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20056,PHI:122997,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,Cysteine changed to alanine at 105th position,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20057,PHI:122998,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,Cysteine changed to alanine at 84th position,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20058,PHI:122999,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,Cysteine changed to alanine at 99th position,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20059,PHI:123000,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,Cysteine changed to alanine at 113th position,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20060,PHI:123001,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,Cysteine changed to alanine at 126th position,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20061,PHI:123002,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,Cysteine changed to alanine at 129th position,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20062,PHI:123003,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,Cysteine changed to alanine at 131st position,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Xiaoyan 22,,,spike,orphan secreted protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions. Tissue 'flowering wheat heads'.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20063,PHI:123004,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20064,PHI:123005,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20065,PHI:123006,UniProt,I1S411,GenBank,CEF79768,,,PH-1,osp24 (FGSG_11564),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,flower,orphan secreted protein,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,32873802,PubMed,10.1038/s41467-020-18240-y,Nat Commun. 2020 Sep 1;11(1):4382,liuhuiquan@nwsuaf.edu.cn,"Osp24 functions as a cytoplasmic effector by competing against TaFROG for binding with TaSnRK1α, demonstrating the counteracting roles of orphan proteins of both host and fungal pathogens during their interactions.",C Jiang 2020,2020,11 genes,Jiang-2020-An orphan protein of Fusarium grami,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20066,PHI:123007,,no data found,,,,,,VdSCP76,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,CFEM domain-containing proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20067,PHI:123008,,no data found,,,,,,VdSCP77,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,CFEM domain-containing proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20068,PHI:123007,,no data found,,,,,,VdSCP76,,,,,,PHI:123008,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,CFEM domain-containing proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20069,PHI:123008,,no data found,,,,,,VdSCP77,,,,,,PHI:123007,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,CFEM domain-containing proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20070,PHI:123009,,no data found,,,,,,VdSCP33,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,CFEM domain-containing proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20071,PHI:123010,UniProt,G2XDH0,GenBank,EGY17038,,,VdLs.17,VdSCP41,chromosome 6,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,effector SCP41,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20072,PHI:123011,,no data found,,,,,,VdSCP43,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,CFEM domain-containing proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20073,PHI:123012,,no data found,,,,,,VdSCP72,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,CFEM domain-containing proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20074,PHI:123013,,no data found,,,,,,VdSCP99,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,CFEM domain-containing proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20075,PHI:123014,,no data found,,,,,,VdSCP116,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,CFEM domain-containing proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20076,PHI:123015,,no data found,,,,,,VdSCP120,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,leaf,CFEM domain-containing proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20077,PHI:123016,,no data found,,,,,,VdSCP76,,Asn residue was substituted with the Asp residue in VdSCP76 (VdSCP76N43D),,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,CFEM domain-containing proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20078,PHI:123017,,no data found,,,,,,VdSCP77,,Asn residue was substituted with the Asp residue in VdSCP77 (VdSCP77N47D),,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,CFEM domain-containing proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20079,PHI:123018,,no data found,,,,,,VdSCP76,,signal peptide deletion mutants from VdSCP76 (VdSCP76ΔSP) with VdEG1,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,CFEM domain-containing proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20080,PHI:123019,,no data found,,,,,,VdSCP77,,signal peptide deletion mutants from VdSCP77 (VdSCP77ΔSP) with VdEG1,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,CFEM domain-containing proteins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35197059,PubMed,10.1186/s12915-022-01254-x,BMC Biol. 2022 Feb 23;20(1):55,daixiaofeng_caas@126.com,"VdSCP76 and VdSCP77 showed the broadest-spectrum immunity suppression ability and highest virulence related to the potential conversed iron binding site mutation (Asp>>Asn), compared to other seven CFEM-containing VdSCPs that probably involves in iron predation.",D Wang 2022,2022,9 genes,Wang-2022-Verticillium dahliae CFEM proteins m,BATCH_111B,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20081,PHI:123020,UniProt,Q46941,GenBank,AAC75885,,,K-12,yqeH,,,,,,,562,Escherichia coli,,APEC 40,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryo fibroblast cell line,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35436977,PubMed,10.1186/s13567-022-01049-6,Vet Res . 2022 Apr 18;53(1):30,pxcpyq@sina.com,The APEC40-ΔyqeH mutant showed reduced adherence to and invasion of DF-1 cells compared with those of WT strain APEC40.,L Yin 2022,2022,1 gene,Yin-2022-YqeH contributes to avian pathogenic,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20082,PHI:123021,UniProt,Q46941,GenBank,AAC75885,,,K-12,yqeH,,,,,,,562,Escherichia coli,,APEC 40,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),Roman chicks,,,blood; liver; spleen; kidney,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35436977,PubMed,10.1186/s13567-022-01049-6,Vet Res . 2022 Apr 18;53(1):30,pxcpyq@sina.com,"The mortality rate was signifcantly lower after infection with strain APEC40-ΔyqeH(50%, 4/8) than after infection with strain APEC40 (100%, 8/8). The mortality rate after infection with strain APEC40-CΔyqeH was restored to 75% (6/8) of the WT level. The bacterial loads of APEC40-ΔyqeH were signifcantly lower than those of WT strain APEC40. The bacterial loads of APEC40-ΔyqeHwere signifcantly lower than those of WT strain APEC40",L Yin 2022,2022,1 gene,Yin-2022-YqeH contributes to avian pathogenic,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20083,PHI:123022,UniProt,Q01565,GenBank,ADM99376,,,3937,outD,,,,,,,204038,Dickeya dadantii,,A6533,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Jazzy,,,tuber,general secretion pathway protein D,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35417462,PubMed,10.1371/journal.pone.0265075. eCollection 2022,PLoS One . 2022 Apr 13;17(4):e0265075,guy.condemine@insa-lyon.fr,Host gene study,G Condemine 2022,2022,3 genes,Condemine-2022-Identification of new Dickeya d,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20084,PHI:123023,UniProt,E0SMB4,GenBank,ADM99449,,,3937,SvfA (Dda3937_01687),,,,,,,204038,Dickeya dadantii,,,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Jazzy,,,tuber,general secretion pathway protein D,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35417462,PubMed,10.1371/journal.pone.0265075. eCollection 2022,PLoS One . 2022 Apr 13;17(4):e0265075,guy.condemine@insa-lyon.fr,Host gene study,G Condemine 2022,2022,3 genes,Condemine-2022-Identification of new Dickeya d,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20085,PHI:123024,UniProt,E0SBX4,GenBank,ADM98442,,,3937,SvfB (Dda3937_00585),,,,,,,204038,Dickeya dadantii,,,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Jazzy,,,tuber,general secretion pathway protein D,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35417462,PubMed,10.1371/journal.pone.0265075. eCollection 2022,PLoS One . 2022 Apr 13;17(4):e0265075,guy.condemine@insa-lyon.fr,Host gene study,G Condemine 2022,2022,3 genes,Condemine-2022-Identification of new Dickeya d,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20086,PHI:123023,UniProt,E0SMB4,GenBank,ADM99449,,,3937,SvfA (Dda3937_01687),,,,,,PHI:123024,204038,Dickeya dadantii,,,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Jazzy,,,tuber,general secretion pathway protein D,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35417462,PubMed,10.1371/journal.pone.0265075. eCollection 2022,PLoS One . 2022 Apr 13;17(4):e0265075,guy.condemine@insa-lyon.fr,Host gene study,G Condemine 2022,2022,3 genes,Condemine-2022-Identification of new Dickeya d,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20087,PHI:123024,UniProt,E0SBX4,GenBank,ADM98442,,,3937,SvfB (Dda3937_00585),,,,,,PHI:123023,204038,Dickeya dadantii,,,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Jazzy,,,tuber,general secretion pathway protein D,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35417462,PubMed,10.1371/journal.pone.0265075. eCollection 2022,PLoS One . 2022 Apr 13;17(4):e0265075,guy.condemine@insa-lyon.fr,Host gene study,G Condemine 2022,2022,3 genes,Condemine-2022-Identification of new Dickeya d,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20088,PHI:123025,UniProt,Q9HWP9,GenBank,AAG07519,,,PAO1,MpaR,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bronchoalveolar lavage fluid; lung; blood; spleen,HTH gntR-type domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,32748556,PubMed,10.1111/mmi.14584. Epub 2020 Aug 18,Mol Microbiol . 2020 Nov;114(5):857-869,lianghh@nwu.edu.cn,"The colony-forming units in bronchoalveolar lavage fluid, blood, lung and spleen from ΔmpaR-infected mice at 24 hr were significantly lower than those of mice challenged with wild-type PAO1 or the complemented strain.",T Wang,2020,1 gene,Wang-2020-Coordinated regulation of anthranila,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20089,PHI:123026,UniProt,Q8Y5W0,GenBank,CAD00023,,,EGD-e,ribU,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,riboflavin transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35316134,PubMed,10.1073/pnas.2122173119,Proc Natl Acad Sci U S A . 2022 Mar 29;119(13):e2122173119,portnoy@berkeley.edu,Listeria monocytogenes mutant lacking the putative riboflavin transporter (RibU) was completely avirulent in mice but had no detectable growth defect in nutrient-rich media.,R Rivera-Lugo 2022,2022,3 genes,Rivera-Lugo-2022-RibU is an essential determin,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20090,PHI:123027,UniProt,Q8Y7F2,GenBank,CAC99407,,,EGD-e,ribC,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,bifunctional riboflavin kinase/FMN adenylyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35316134,PubMed,10.1073/pnas.2122173119,Proc Natl Acad Sci U S A . 2022 Mar 29;119(13):e2122173119,portnoy@berkeley.edu,Listeria monocytogenes mutant lacking the putative riboflavin transporter (RibU) was completely avirulent in mice but had no detectable growth defect in nutrient-rich media.,R Rivera-Lugo 2022,2022,3 genes,Rivera-Lugo-2022-RibU is an essential determin,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20091,PHI:123028,UniProt,Q8Y914,GenBank,CAC98806,,,EGD-e,ribF,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,FAD synthetase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35316134,PubMed,10.1073/pnas.2122173119,Proc Natl Acad Sci U S A . 2022 Mar 29;119(13):e2122173119,portnoy@berkeley.edu,Listeria monocytogenes mutant lacking the putative riboflavin transporter (RibU) was completely avirulent in mice but had no detectable growth defect in nutrient-rich media.,R Rivera-Lugo 2022,2022,3 genes,Rivera-Lugo-2022-RibU is an essential determin,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20092,PHI:123027,UniProt,Q8Y7F2,GenBank,CAC99407,,,EGD-e,ribC,,,,,,PHI:123028,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,bifunctional riboflavin kinase/FMN adenylyltransferase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full; gene complementation,,,NN,35316134,PubMed,10.1073/pnas.2122173119,Proc Natl Acad Sci U S A . 2022 Mar 29;119(13):e2122173119,portnoy@berkeley.edu,Listeria monocytogenes mutant lacking the putative riboflavin transporter (RibU) was completely avirulent in mice but had no detectable growth defect in nutrient-rich media.,R Rivera-Lugo 2022,2022,3 genes,Rivera-Lugo-2022-RibU is an essential determin,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20093,PHI:123028,UniProt,Q8Y914,GenBank,CAC98806,,,EGD-e,ribF,,,,,,PHI:123027,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,FAD synthetase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full; gene complementation,,,NN,35316134,PubMed,10.1073/pnas.2122173119,Proc Natl Acad Sci U S A . 2022 Mar 29;119(13):e2122173119,portnoy@berkeley.edu,Listeria monocytogenes mutant lacking the putative riboflavin transporter (RibU) was completely avirulent in mice but had no detectable growth defect in nutrient-rich media.,R Rivera-Lugo 2022,2022,3 genes,Rivera-Lugo-2022-RibU is an essential determin,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20094,PHI:123029,UniProt,Q8Y5W0,GenBank,CAD00023,,,EGD-e,ribU,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,riboflavin transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35316134,PubMed,10.1073/pnas.2122173119,Proc Natl Acad Sci U S A . 2022 Mar 29;119(13):e2122173119,portnoy@berkeley.edu,Listeria monocytogenes mutant lacking the putative riboflavin transporter (RibU) was completely avirulent in mice but had no detectable growth defect in nutrient-rich media.,R Rivera-Lugo 2022,2022,3 genes,Rivera-Lugo-2022-RibU is an essential determin,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20095,PHI:123030,UniProt,B0XYB9,GenBank,EDP52865,,,A1163,oxrA,,,,,,,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung; bronchoalveolar lavage fluid,oxidation resistance protein,,,,reduced virulence,,,,yes,,,,wild type,,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,NN,34524893,PubMed,10.1128/AEM.01120-21,Appl Environ Microbiol . 2021 Oct 28;87(22):e0112021,lirongpeng@jsnu.edu.cn,The mice subjected toDoxrAmutant infection had a markedly decreased virulence in comparison to the mice subjected to infection with the parental wild-type strain,P Zhai 2021,2021,1 gene,Zhai-2021-The OxrA Protein of Aspergillus fumi,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20096,PHI:123030,,no data found,,,,,,afpA,,,,,,,562,Escherichia coli,,UPEC-46,urinary tract infection,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,34923895,PubMed,10.1080/21505594.2021.2007645,Virulence . 2021 Dec;12(1):3073-3093,tatg.amaral@unifesp.br,"A mutation in afpA (encoding the AFP major pilin) led to the loss of pilin production and assembly, and notably, a strongly reduced adhesion to epithelial cells.",P A Schüroff 2021,2021,1 gene,Schüroff-2021-The aggregate-forming pili (AFP),BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20097,PHI:123031,,no data found,,,,,,afpA,,,,,,,562,Escherichia coli,,UPEC-46,urinary tract infection,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,HT-29 cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,34923895,PubMed,10.1080/21505594.2021.2007645,Virulence . 2021 Dec;12(1):3073-3093,tatg.amaral@unifesp.br,"A mutation in afpA (encoding the AFP major pilin) led to the loss of pilin production and assembly, and notably, a strongly reduced adhesion to epithelial cells.",P A Schüroff 2021,2021,1 gene,Schüroff-2021-The aggregate-forming pili (AFP),BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20098,PHI:123032,,no data found,,,,,,afpA,,,,,,,562,Escherichia coli,,UPEC-46,urinary tract infection,primates,9606,Homo sapiens (related: human),5637 cell line,,,5637 cell,aggregate-forming pili protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,34923895,PubMed,10.1080/21505594.2021.2007645,Virulence . 2021 Dec;12(1):3073-3093,tatg.amaral@unifesp.br,"A mutation in afpA (encoding the AFP major pilin) led to the loss of pilin production and assembly, and notably, a strongly reduced adhesion to epithelial cells.",P A Schüroff 2021,2021,1 gene,Schüroff-2021-The aggregate-forming pili (AFP),BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20099,PHI:123033,UniProt,Q4X0T3,GenBank,EAL93532,,,Af293,sat1,,,,,,,746128,Aspergillus fumigatus,,IFM40808,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,intracellular protein transport protein,,,,reduced virulence,,,,,,defective,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35107385,PubMed,10.1128/spectrum.01558-21. Epub 2022 Feb 2,Microbiol Spectr . 2022 Feb 23;10(1):e0155821,wli99@jlu.edu.cn,The deletion ofsat1 exhibited severe growth defects and significantly increased the nematode and mouse survival rates,Y Wei 2022,2022,1 gene,Wei-2022-The sat1 Gene Is Required for the Gro,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20100,PHI:123034,UniProt,Q4X0T3,GenBank,EAL93532,,,Af293,sat1,,,,,,,746128,Aspergillus fumigatus,,IFM40808,invasive aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,intracellular protein transport protein,,,,reduced virulence,,,,,,defective,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35107385,PubMed,10.1128/spectrum.01558-21. Epub 2022 Feb 2,Microbiol Spectr . 2022 Feb 23;10(1):e0155821,wli99@jlu.edu.cn,The deletion ofsat1 exhibited severe growth defects and significantly increased the nematode and mouse survival rates,Y Wei 2022,2022,1 gene,Wei-2022-The sat1 Gene Is Required for the Gro,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20101,PHI:123035,,no data found,,,,,,VdTRP,,,,ASP F2,UniProt: G2X2M7; GenBank: EGY23113,,27337,Verticillium dahliae,,V991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 13,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,H2O2; KCl; Congo red; sorbitol,H2O2: CHEBI:16240; KCl: CHEBI:32588; congo red: CHEBI:34653; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,35478269,PubMed,10.1111/1751-7915.14066,Microb Biotechnol. 2022 Apr 27,20131913@cqnu.edu.cn,"The deletion mutant was analysed to reveal that VdTRP is required for microsclerotial production, but it is not essential for stress resistance, carbon utilization and pathogenicity of V. dahliae.",C Guo 2022,2022,1 gene,Guo-2022-Identification of VdASP F2-interactin,BATCH_112A,2022-05-01,MC,,,,,,,,,,,,,
,,Record 20102,PHI:123036,UniProt,F9FNP1,GenBank,EGU81439,,,Fo5176,CLR1 (FOXB_08021),,,,,,,5507,Fusarium oxysporum,660025,Fo5176,Fusarium wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,root,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35442735,PubMed,10.1126/sciadv.abl9734. Epub 2022 Apr 20,Sci Adv. 2022 Apr 22;8(16):eabl9734,clara_sanchez@ethz.ch,Loss of CLR1 led to a significant increase in virulence in both the Arabidopsis and tomato pathogenic forms of Fo,F M Gámez-Arjona 2022,2022,2 genes,Gámez-Arjona-2022-Impairment of the cellulose,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20103,PHI:123037,UniProt,A0A0J9V944,GenBank,KNB07481,,,4287,CLR1 (FOXG_08626),chromosome 2a,,,,,,5507,Fusarium oxysporum,660025,f. sp. lycopersici strain FGSC9935,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Monika,,,root,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35442735,PubMed,10.1126/sciadv.abl9734. Epub 2022 Apr 20,Sci Adv. 2022 Apr 22;8(16):eabl9734,clara_sanchez@ethz.ch,Loss of CLR1 led to a significant increase in virulence in both the Arabidopsis and tomato pathogenic forms of Fo,F M Gámez-Arjona 2022,2022,2 genes,Gámez-Arjona-2022-Impairment of the cellulose,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20104,PHI:123037,UniProt,G1XUA8,GenBank,EGX43651,,,ATCC 24927,AoRho2 (AOL_s00215g387),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,Rho GTPase,,,,reduced virulence,,,,,,aberrant,,wild type,reduced,no,H2O2; menadione; NaCl; sorbitol; Congo red; sodium dodecyl sulfate,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,NN,35019695,PubMed,10.1128/spectrum.01759-21. Epub 2022 Jan 12,Microbiol Spectr. 2022 Feb 23;10(1):e0175921,kqzhang1@ynu.edu.cn,There was no significant difference in morphology and number of traps between the ΔAorho2 mutants and the WT strain. 94.5% of nematodes were captured by the ΔAorho2 mutant.,X Yang 2018,2022,3 genes,Yang-2022-Transcriptomic Analysis Reveals That,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20105,PHI:123038,UniProt,G1X415,GenBank,EGX52049,,,ATCC 24927,AoCdc42 (AOL_s00043g439),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,Rho GTPase,,,,reduced virulence,,,,,,reduced; aberrant,,reduced; aberrant,reduced,no,H2O2; menadione; NaCl; sorbitol; Congo red; sodium dodecyl sulfate,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,NN,35019695,PubMed,10.1128/spectrum.01759-21. Epub 2022 Jan 12,Microbiol Spectr. 2022 Feb 23;10(1):e0175922,kqzhang1@ynu.edu.cn,Disruption of the ΔAocdc42 gene resulted in reduced conidial production. 57.7% of nematodes were captured by the ΔAocdc42 mutants at 36 h,X Yang 2018,2022,3 genes,Yang-2022-Transcriptomic Analysis Reveals That,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20106,PHI:123039,UniProt,G1XD68,GenBank,EGX48950,,,ATCC 24927,AoRac (AOL_s00079g171),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,Rho GTPase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,reduced,no,H2O2; menadione; NaCl; sorbitol; Congo red; sodium dodecyl sulfate,H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,NN,35019695,PubMed,10.1128/spectrum.01759-21. Epub 2022 Jan 12,Microbiol Spectr. 2022 Feb 23;10(1):e0175923,kqzhang1@ynu.edu.cn,The colony morphologies of the Δaorac mutant strains were irregular. Disruption of the ΔAorac gene led to loss of the ability to produce conidia. ΔAorac mutants did not produce traps until 48 h.,X Yang 2018,2022,3 genes,Yang-2022-Transcriptomic Analysis Reveals That,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20107,PHI:123040,UniProt,E0SFK8,GenBank,ADM96379,,,3937,cpxR,,,,,,,204038,Dickeya dadantii,198628,pCL1920,soft rot,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35460168,PubMed,10.1111/mpp.13219,Mol Plant Pathol. 2022 Apr 23,yu32@uwm.edu,"The reduced virulence of the ΔcpxR pCL1920 strain on potato tubers was recovered in complemented ΔcpxR pCLcpxR, which showed similar maceration to the WT strain.",D Jiang 2022,2022,1 gene,Jiang-2022-The phytopathogen Dickeya dadantii,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20108,PHI:123041,UniProt,G5EHR8,GenBank,EHA46047,,,70-15,Mokap119 (MGG_02927),chromosome 7,,,,,,318829,Magnaporthe oryzae,1348879,B157 (MAT1-2),blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf; root,beta-importin,,,,loss of pathogenicity,,,,,,defective,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,31487436,PubMed,10.1111/cmi.13114. Epub 2019 Oct 9,Cell Microbiol. 2020 Jan;22(1):e13114,dengyz@scau.edu.cn,"The mokap119Δmutant displayed defects in mycelial growth, pigmentation, conidiation, and pathogenicity.",S Zhang 2020,2020,1 gene,Zhang-2019-Karyopherin MoKap119-mediated nucle,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20109,PHI:123042,UniProt,G5EHR8,GenBank,EHA46047,,,70-15,Mokap119 (MGG_02927),chromosome 7,,,,,,318829,Magnaporthe oryzae,1348879,B157 (MAT1-2),blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,beta-importin,,,,loss of pathogenicity,,,,,,defective,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,31487436,PubMed,10.1111/cmi.13114. Epub 2019 Oct 10,Cell Microbiol. 2020 Jan;22(1):e13114,dengyz@scau.edu.cn,"The mokap119Δmutant displayed defects in mycelial growth, pigmentation, conidiation, and pathogenicity.",S Zhang 2020,2020,1 gene,Zhang-2019-Karyopherin MoKap119-mediated nucle,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20110,PHI:123043,UniProt,A7F3R6,GenBank,EDN97387,,,1980,SsNEP2 (SS1G_11912),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,stem rot,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,ethylene-inducible peptide 2,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35456121,PubMed,10.3390/pathogens11040446,Pathogens. 2022 Apr 7;11(4):446,xstone0505@hunau.edu.cn,"SsNEP2 contributes to the virulence of S. sclerotiorum without affecting the development of mycelia, the formation of appressoria, or the secretion of oxalic acid.",C Yang 2022,2022,1 gene,Yang-2022-SsNEP2 Contributes to the Virulence,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20111,PHI:123044,UniProt,A7F3R6,GenBank,EDN97387,,,1980,SsNEP2 (SS1G_11912),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,stem rot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,ethylene-inducible peptide 2,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35456121,PubMed,10.3390/pathogens11040446,Pathogens. 2022 Apr 7;11(4):446,xstone0505@hunau.edu.cn,"SsNEP2 contributes to the virulence of S. sclerotiorum without affecting the development of mycelia, the formation of appressoria, or the secretion of oxalic acid.",C Yang 2022,2022,1 gene,Yang-2022-SsNEP2 Contributes to the Virulence,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20112,PHI:123045,UniProt,G4MVP3,GenBank,EHA54959,,,70-15,MoIst1 (MGG_01765),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,accessory component of ESCRT-III,,,,reduced virulence,,,yes,,,reduced,,reduced,wild type,no,H2O2; paraquat; NaCl; sorbitol; KCl,H2O2: CHEBI:16240; paraquat: CHEBI:34905; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,35463448,PubMed,10.3389/fpls.2022.845139. eCollection 2022,Front Plant Sci. 2022 Apr 7;13:845139,xhliu@zju.edu.cn,"Disruption of MoIst1 leads to a significant decrease in sporulation and formation of appressoria, defects in response to oxidative stress, cell wall stress, hyperosmotic stress, and reduced pathogenicity.",L Sun 2022,2022,1 gene,"Sun-2022-A Subunit of ESCRT-III, MoIst1, Is In",BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20113,PHI:123046,UniProt,G4MVP3,GenBank,EHA54959,,,70-15,MoIst1 (MGG_01765),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,accessory component of ESCRT-III,,,,reduced virulence,,,yes,,,reduced,,reduced,wild type,no,H2O2; paraquat; NaCl; sorbitol; KCl,H2O2: CHEBI:16240; paraquat: CHEBI:34905; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,35463448,PubMed,10.3389/fpls.2022.845139. eCollection 2022,Front Plant Sci. 2022 Apr 7;13:845139,xhliu@zju.edu.cn,"Disruption of MoIst1 leads to a significant decrease in sporulation and formation of appressoria, defects in response to oxidative stress, cell wall stress, hyperosmotic stress, and reduced pathogenicity.",L Sun 2022,2022,1 gene,"Sun-2022-A Subunit of ESCRT-III, MoIst1, Is In",BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20114,PHI:123047,UniProt,A5CLZ4,GenBank,CAN00074,,,NCPPB 382,ChpG (CMM_0059),,marker exchange mutant CmΩchpG; catalytically inactive ChpG mutant S231A was introduced into chpG or marker exchange mutant CmΩchpG,,,,,28447,Clavibacter michiganensis,,CMM101,bacterial wilt; bacterial canker,eudicots,4111,Solanum melongena (related: eggplant),cv. Black Queen; cv. Baladi; cv. Japanese Finger; cv. Thai Long Green; cv. Little Finger; cv. Bianca; cv. Tudla; cv. Aragon; cv. 104952; cv. 104954; cv. 102795; cv. 102797,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35441490,PubMed,10.1111/mpp.13215,Mol Plant Pathol. 2022 Jul;23(7):933-946,doront@volcani.agri.gov.il,"Eggplant leaves infiltrated with the chpG marker- exchanged mutant (CmΩchpG) failed to develop an hypersensitive response. Virulence assays found that while wild-type Cm and the CmΩchpG complemented strain were nonpathogenic on eggplant, CmΩchpG caused wilt and canker symptoms. ChpG-mediated avirulence interactions were disabled by alanine substitution of serine231 of the serine protease catalytic triad, suggesting that protease activity is required for immune recognition of ChpG.",R K Verma 2022,2022,4 genes,Verma-2022-Immune recognition of the secreted,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20115,PHI:123047,UniProt,A5CLZ4,GenBank,CAN00074,,,NCPPB 382,ChpG (CMM_0059),,marker exchange mutant CmΩchpG; catalytically inactive ChpG mutant S231A was introduced into chpG,,,,,28447,Clavibacter michiganensis,,CMM101,bacterial wilt; bacterial canker,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35441490,PubMed,10.1111/mpp.13215,Mol Plant Pathol. 2022 Jul;23(7):933-946,doront@volcani.agri.gov.il,"No significant difference was observed in the severity of disease symptoms and bacterial colonization between the chpGmutant and the wild- type strain in tomato. ChpG-mediated avirulence interactions were disabled by alanine substitution of serine231 of the serine protease catalytic triad, suggesting that protease activity is required for immune recognition of ChpG.",R K Verma 2022,2022,4 genes,Verma-2022-Immune recognition of the secreted,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20116,PHI:123048,UniProt,A5CLY7,GenBank,CAN00066,,,NCPPB 382,ChpC (CMM_0052),,marker exchange mutant CmΩchpC,,,,,28447,Clavibacter michiganensis,,CMM101,bacterial wilt; bacterial canker,eudicots,4111,Solanum melongena (related: eggplant),cv. Black Queen,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35441490,PubMed,10.1111/mpp.13215,Mol Plant Pathol. 2022 Jul;23(7):933-946,doront@volcani.agri.gov.il,Eggplant leaves infiltrated with the chpC marker-exchanged mutant (CmΩchpC) developed hypersensitive response same as wild-type.,R K Verma 2022,2022,4 genes,Verma-2022-Immune recognition of the secreted,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20117,PHI:123049,UniProt,A5CRN8,GenBank,CAN01748,,,NCPPB 382,ChpE (CMM_0039),,marker exchange mutant CmΩchpE,,,,,28447,Clavibacter michiganensis,,CMM101,bacterial wilt; bacterial canker,eudicots,4111,Solanum melongena (related: eggplant),cv. Black Queen,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35441490,PubMed,10.1111/mpp.13215,Mol Plant Pathol. 2022 Jul;23(7):933-946,doront@volcani.agri.gov.il,Eggplant leaves infiltrated with the chpE marker-exchanged mutant (CmΩchpE) developed hypersensitive response same as wild-type.,R K Verma 2022,2022,4 genes,Verma-2022-Immune recognition of the secreted,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20118,PHI:123050,UniProt,A5CLY8,GenBank,CAN00068,,,NCPPB 382,ChpE (CMM_0053),,marker exchange mutant CmΩchpF,,,,,28447,Clavibacter michiganensis,,CMM101,bacterial wilt; bacterial canker,eudicots,4111,Solanum melongena (related: eggplant),cv. Black Queen,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35441490,PubMed,10.1111/mpp.13215,Mol Plant Pathol. 2022 Jul;23(7):933-946,doront@volcani.agri.gov.il,Eggplant leaves infiltrated with the chpF marker-exchanged mutant (CmΩchpF) developed hypersensitive response same as wild-type.,R K Verma 2022,2022,4 genes,Verma-2022-Immune recognition of the secreted,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20119,PHI:123051,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,14028S,chiA (STM14_0022),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,ileum,putative exochitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010167,jbehnsen@uic.edu,The chitinase-deficient strain displayed markedly reduced invasion of ileal tissue.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20120,PHI:123051,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,14028S,chiA (STM14_0022),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,colon,putative exochitinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010168,jbehnsen@uic.edu,There was no defect in the ability of the chitinase-deficient strains to invade colonic tissue or colonize the colon.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20121,PHI:123052,UniProt,A0A0F6AX37,GenBank,ACY86809,,,14028S,STM0233 (STM14_0275),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,ileum,putative exochitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010169,jbehnsen@uic.edu,The chitinase-deficient strain displayed markedly reduced invasion of ileal tissue.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20122,PHI:123052,UniProt,A0A0F6AX37,GenBank,ACY86809,,,14028S,STM0233 (STM14_0275),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,colon,putative exochitinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010170,jbehnsen@uic.edu,There was no defect in the ability of the chitinase-deficient strains to invade colonic tissue or colonize the colon.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20123,PHI:123051,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,14028S,chiA (STM14_0022),,,,,,PHI:123052,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,ileum,putative exochitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010171,jbehnsen@uic.edu,The chitinase-deficient strain displayed markedly reduced invasion of ileal tissue.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20124,PHI:123052,UniProt,A0A0F6AX37,GenBank,ACY86809,,,14028S,STM0233 (STM14_0275),,,,,,PHI:123051,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,ileum,putative exochitinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010172,jbehnsen@uic.edu,The chitinase-deficient strain displayed markedly reduced invasion of ileal tissue.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20125,PHI:123051,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,14028S,chiA (STM14_0022),,,,,,PHI:123052,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,colon,putative exochitinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010173,jbehnsen@uic.edu,There was no defect in the ability of the chitinase-deficient double mutant strains to invade colonic tissue or colonize the colon.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20126,PHI:123052,UniProt,A0A0F6AX37,GenBank,ACY86809,,,14028S,STM0233 (STM14_0275),,,,,,PHI:123051,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,colon,putative exochitinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010174,jbehnsen@uic.edu,There was no defect in the ability of the chitinase-deficient double mutant strains to invade colonic tissue or colonize the colon.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20127,PHI:123051,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,14028S,chiA (STM14_0022),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,even-toed ungulates,9823,Sus scrofa (related: Pig),IPEC-1 cell line,,,IPEC-1 cell,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010167,jbehnsen@uic.edu,The chitinase-deficient strain displayed markedly reduced invasion of ileal tissue.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20128,PHI:123052,UniProt,A0A0F6AX37,GenBank,ACY86809,,,14028S,STM0233 (STM14_0275),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,even-toed ungulates,9823,Sus scrofa (related: Pig),IPEC-1 cell line,,,IPEC-1 cell,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010167,jbehnsen@uic.edu,The chitinase-deficient strain displayed markedly reduced invasion of ileal tissue.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20129,PHI:123051,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,14028S,chiA (STM14_0022),,,,,,PHI:123052,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,even-toed ungulates,9823,Sus scrofa (related: Pig),IPEC-1 cell line,,,IPEC-1 cell,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010167,jbehnsen@uic.edu,The chitinase-deficient double mutant strain displayed markedly reduced invasion of ileal tissue.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20130,PHI:123052,UniProt,A0A0F6AX37,GenBank,ACY86809,,,14028S,STM0233 (STM14_0275),,,,,,PHI:123051,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,even-toed ungulates,9823,Sus scrofa (related: Pig),IPEC-1 cell line,,,IPEC-1 cell,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010167,jbehnsen@uic.edu,The chitinase-deficient double mutant strain displayed markedly reduced invasion of ileal tissue.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20131,PHI:123051,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,14028S,chiA (STM14_0022),,,,,,PHI:123052,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,primates,9606,Homo sapiens (related: human),T84 cell line,,,T-84 cell,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010167,jbehnsen@uic.edu,The chitinase-deficient double mutant strain displayed markedly reduced invasion of T84 cells.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20132,PHI:123052,UniProt,A0A0F6AX37,GenBank,ACY86809,,,14028S,STM0233 (STM14_0275),,,,,,PHI:123051,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,primates,9606,Homo sapiens (related: human),T84 cell line,,,T-84 cell,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010167,jbehnsen@uic.edu,The chitinase-deficient double mutant strain displayed markedly reduced invasion of T84 cells.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20133,PHI:123051,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,14028S,chiA (STM14_0022),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,primates,9606,Homo sapiens (related: human),T84 cell line,,,T-84 cell,putative exochitinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010167,jbehnsen@uic.edu,The chiA-deficient strain did not show significant reduction in invasion of T84 cells.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20134,PHI:123052,UniProt,A0A0F6AX37,GenBank,ACY86809,,,14028S,STM0233 (STM14_0275),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain IR715,gastroenteritis,primates,9606,Homo sapiens (related: human),T84 cell line,,,T-84 cell,putative exochitinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35482787,PubMed,10.1371/journal.ppat.1010167. eCollection 2022 Apr,PLoS Pathog . 2022 Apr 28;18(4):e1010167,jbehnsen@uic.edu,The chiA-deficient strain did not show significant reduction in invasion of T84 cells.,J R Devlin 2022,2022,2 genes,Devlin-2022-Salmonella enterica serovar Typhim,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20135,PHI:123053,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,,,,,,5476,Candida albicans,237561,M2057,vulvovaginal candidiasis,primates,9606,Homo sapiens (related: human),LAD2 cell line,,,LAD-2 cell,"candidalysin, a cytolytic peptide toxin",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35420364,PubMed,10.1007/s10875-022-01267-9,Clin Immunol. 2022 Apr 14,francois@juntendo.ac.jp,"C. albicans strain lacking candidalysin (M2057: ece1-null) failed to induce the secretion of IL-8, MCP-1, MIP-1α, and MIP-1β.",P Song 2022,2022,1 gene,"Song-2022-Candidalysin, a Virulence Factor of",BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20136,PHI:123053,UniProt,Q07730,GenBank,AOW29105,,,SC5314,ECE1,chromosome 4,,,,,,5476,Candida albicans,237561,M2174,vulvovaginal candidiasis,primates,9606,Homo sapiens (related: human),LAD2 cell line,,,LAD-2 cell,"candidalysin, a cytolytic peptide toxin",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,NN,35420364,PubMed,10.1007/s10875-022-01267-9,Clin Immunol. 2022 Apr 14,francois@juntendo.ac.jp,"C. albicans strain lacking candidalysin (M2174: ece1 + ECE1 lacking the candidalysin sequence only) failed to induce the secretion of IL-8, MCP-1, MIP-1α, and MIP-1β.",P Song 2022,2022,1 gene,"Song-2022-Candidalysin, a Virulence Factor of",BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20137,PHI:123054,UniProt,no data found,GenBank,,,,,CgSAT4,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,anthracnose,eudicots,3690,Populus x canadensis (related: carolina poplar),cv. Nanlin 895,,,leaf,serine/threonine kinase SAT4,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35463420,PubMed,10.3389/fpls.2022.773898. eCollection 2022,Front Plant Sci. 2022 Apr 7;13:773898,lhuang@njfu.edu.cn,"Targeted gene deletion showed that CgSat4 was essential for vegetative growth, sporulation, and full virulence.",Y T Pan 2022,2022,1 gene,Pan-2022-Involvement of Protein Kinase CgSat4,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20138,PHI:123055,UniProt,no data found,GenBank,,,,,CgSAT4,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,anthracnose,seed plants,28977,Cunninghamia lanceolata (related: china fir),,,,leaf,serine/threonine kinase SAT4,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35463420,PubMed,10.3389/fpls.2022.773898. eCollection 2022,Front Plant Sci. 2022 Apr 7;13:773899,lhuang@njfu.edu.cn,"Targeted gene deletion showed that CgSat4 was essential for vegetative growth, sporulation, and full virulence.",Y T Pan 2022,2022,1 gene,Pan-2022-Involvement of Protein Kinase CgSat4,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20139,PHI:123056,UniProt,no data found,GenBank,,,,,CgSAT4,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,anthracnose,flowering plants,215539,Liriodendron chinense x Liriodendron tulipifera (no common name found),,,,leaf,serine/threonine kinase SAT4,,,,reduced virulence,,yes,yes,yes,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35463420,PubMed,10.3389/fpls.2022.773898. eCollection 2022,Front Plant Sci. 2022 Apr 7;13:773900,lhuang@njfu.edu.cn,"Targeted gene deletion showed that CgSat4 was essential for vegetative growth, sporulation, and full virulence.",Y T Pan 2022,2022,1 gene,Pan-2022-Involvement of Protein Kinase CgSat4,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20140,PHI:123057,UniProt,A0A1D8PCD2,GenBank,AOW25796,,,SC5314,CaNMA111,chromosome 1,,,,,,5476,Candida albicans,,,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,pro-apoptotic serine protease NMA111,,,,increased virulence (hypervirulence),,yes,,,,,,increased,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35534671,PubMed,10.1038/s41598-022-11682-y,Sci Rep. 2022 May 9;12(1):7574,jmkim@cnu.ac.kr,The Canma111/Canma111 deletion strain showed hyperflamentation phenotype and increased virulence in a mouse infection model.,M Nam 2022,2022,2 genes,Nam-2022-Roles of the pro-apoptotic factors Ca,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20141,PHI:123058,UniProt,no data found,GenBank,,,,,Caybh3,,,,,,,5476,Candida albicans,,,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,homolog of BH3-only protein,,,,increased virulence (hypervirulence),,yes,,,,,,increased,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35534671,PubMed,10.1038/s41598-022-11682-y,Sci Rep. 2022 May 9;12(1):7574,jmkim@cnu.ac.kr,The Canma111/Canma111 deletion strain showed hyperflamentation phenotype and increased virulence in a mouse infection model.,M Nam 2022,2022,2 genes,Nam-2022-Roles of the pro-apoptotic factors Ca,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20142,PHI:123059,,no data found,,,,,,Cssp1,,,,,,,45130,Bipolaris sorokiniana,,Lankao 9-3,rot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Aikang 58,,,leaf,mitogen-activated protein kinases,,,salicylic acid synthesis pathway,effector (plant avirulence determinant),,no,no,yes,,aberrant; reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,34741560,PubMed,10.1111/mpp.13155,Mol Plant Pathol. 2022 Feb;23(2):218-236,shengliding@henau.edu.cn,"Compared with the wild type, the deletion mutant ΔCssp1displayed less radial growth on potato dextrose agar plates and produced fewer spores. The pathogenicity of the deletion mutant in wheat was attenuated even though appressoria still penetrated the host. In B. sorokiniana- infected wheat leaves, the salicylic acid- regulated genes TaPAL, TaPR1, and TaPR2were down- regulated in the ΔCssp1strain compared with the wild- type strain.",W Zhang 2022,2022,1 gene,"Zhang-2021-A novel effector, CsSp1, from Bipol",BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20143,PHI:123060,UniProt,J4URE7,GenBank,EJP68072,,,ARSEF 2860,flbA (EJP68072),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,regulator of G protein signaling,,,,reduced virulence,,,,yes,,reduced,,wild type,,no,menadione; Congo red; calcofluor white; NaCl; KCl; sorbitol; H2O2,menadione: CHEBI:28869; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35448565,PubMed,10.3390/jof8040334,J Fungi (Basel). 2022 Mar 23;8(4):334,mgfeng@zju.edu.cn,The fungal virulence against a model insect was attenuated in the absence of flbA. Formation of hyphal bodies and conidial yield was reduced in the flbA deletion mutant strain.,C T Guo 2022,2022,5 genes,Guo-2022-Differential Roles of Five Fluffy Gen,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20144,PHI:123061,UniProt,J4KR49,GenBank,EJP70334,,,ARSEF 2860,flbC (EJP70334),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative C2H2 zinc finger protein,,,,reduced virulence,,,,yes,,reduced,,wild type,,no,menadione; Congo red; calcofluor white; NaCl; KCl; sorbitol; H2O2,menadione: CHEBI:28869; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35448565,PubMed,10.3390/jof8040334,J Fungi (Basel). 2022 Mar 23;8(4):334,mgfeng@zju.edu.cn,The fungal virulence against a model insect was attenuated in the absence of flbC. Formation of hyphal bodies and conidial yield was reduced in the flbC deletion mutant strain.,C T Guo 2022,2022,5 genes,Guo-2022-Differential Roles of Five Fluffy Gen,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20145,PHI:123062,UniProt,J5JDG2,GenBank,EJP63983,,,ARSEF 2860,flbB (EJP63983),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,bZip-type transcription factor,,,,reduced virulence,,,,,,reduced,,wild type,,no,menadione; Congo red; calcofluor white; NaCl; KCl; sorbitol; H2O2,menadione: CHEBI:28869; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35448565,PubMed,10.3390/jof8040334,J Fungi (Basel). 2022 Mar 23;8(4):334,mgfeng@zju.edu.cn,"The ΔflbB LT50, indicative of virulence in insect, was slightly prolonged via cuticle-bypassing infection but not via normal cuticle infection. Conidial yields were reduced in the flbB deletion mutant strain.",C T Guo 2022,2022,5 genes,Guo-2022-Differential Roles of Five Fluffy Gen,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20146,PHI:123063,UniProt,J4W084,GenBank,EJP63935,,,ARSEF 2860,flbD (EJP63935),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Myb-like DNA-binding domain-containing protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,menadione; Congo red; calcofluor white; NaCl; KCl; sorbitol; H2O2,menadione: CHEBI:28869; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35448565,PubMed,10.3390/jof8040334,J Fungi (Basel). 2022 Mar 23;8(4):334,mgfeng@zju.edu.cn,The virulence of ΔflbD did not show any changed compared to wild-type. Neither conidial yield nor biomass level was affected in the ΔflbD cultures.,C T Guo 2022,2022,5 genes,Guo-2022-Differential Roles of Five Fluffy Gen,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20147,PHI:123064,UniProt,J5K6Q5,GenBank,EJP69751,,,ARSEF 2860,flbE (EJP69751),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,AorFlbE-like protein,,,,unaffected pathogenicity,,,,,,reduced,,wild type,,no,menadione; Congo red; calcofluor white; NaCl; KCl; sorbitol; H2O2,menadione: CHEBI:28869; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:30911; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35448565,PubMed,10.3390/jof8040334,J Fungi (Basel). 2022 Mar 23;8(4):334,mgfeng@zju.edu.cn,The virulence of ΔflbE mutant strain did not show any changed compared to wild-type. The ΔflbE mutant exhibited a significant yield decrease of about 15% on day 7 or 9.,C T Guo 2022,2022,5 genes,Guo-2022-Differential Roles of Five Fluffy Gen,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20148,PHI:123065,UniProt,G4NEZ3,GenBank,EHA48719,,,70-15,MoMAS3 (MGG_00703),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,MAS3 protein,,,,reduced virulence,,,,yes,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35526236,PubMed,10.1111/mpp.13226,Mol Plant Pathol. 2022 May 8,rwilson10@unl.edu,"Although the loss of any MAS gene did not affect appressorial formation or vegetative growth, ΔMomas3 mutant strain was reduced in virulence on susceptible CO-39 rice seedlings.",Z Gong 2022,2022,4 genes,Gong-2022-Two Magnaporthe appressoria-specific,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20149,PHI:123066,UniProt,G4MQ19,GenBank,EHA56412,,,70-15,MoMAS5 (MGG_02253),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cell surface protein,,,,reduced virulence,,,,yes,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35526236,PubMed,10.1111/mpp.13226,Mol Plant Pathol. 2022 May 8,rwilson10@unl.edu,"Although the loss of any MAS gene did not affect appressorial formation or vegetative growth, ΔMomas5 mutant strain was reduced in virulence on susceptible CO-39 rice seedlings.",Z Gong 2022,2022,4 genes,Gong-2022-Two Magnaporthe appressoria-specific,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20150,PHI:123065,UniProt,G4NEZ3,GenBank,EHA48719,,,70-15,MoMAS3 (MGG_00703),chromosome 5,,,,,PHI:123066,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,MAS3 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35526236,PubMed,10.1111/mpp.13226,Mol Plant Pathol. 2022 May 8,rwilson10@unl.edu,"Compared to the WT strain, the disease lesions of the double mutant ΔMomas3/ΔMomas5 strain were reduced by 30%.",Z Gong 2022,2022,4 genes,Gong-2022-Two Magnaporthe appressoria-specific,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20151,PHI:123066,UniProt,G4MQ19,GenBank,EHA56412,,,70-15,MoMAS5 (MGG_02253),chromosome 1,,,,,PHI:123065,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cell surface protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35526236,PubMed,10.1111/mpp.13226,Mol Plant Pathol. 2022 May 8,rwilson10@unl.edu,"Compared to the WT strain, the disease lesions of the double mutant ΔMomas3/ΔMomas5 strain were reduced by 30%.",Z Gong 2022,2022,4 genes,Gong-2022-Two Magnaporthe appressoria-specific,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20152,PHI:123067,UniProt,G4NID2,GenBank,EHA47992,,,70-15,MoMAS4 (MGG_09875),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,CAS1 domain-containing protein 1,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,35526236,PubMed,10.1111/mpp.13226,Mol Plant Pathol. 2022 May 8,rwilson10@unl.edu,There was no obvious difference in the number of lesions for ΔMomas4 compared to wild type.,Z Gong 2022,2022,4 genes,Gong-2022-Two Magnaporthe appressoria-specific,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20153,PHI:123068,UniProt,G4ND28,GenBank,EHA48370,,,70-15,MoMAS6 (MGG_00992),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,magnaporthe appressoria-specific protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,35526236,PubMed,10.1111/mpp.13226,Mol Plant Pathol. 2022 May 8,rwilson10@unl.edu,There was no obvious difference in the number of lesions for ΔMomas6 compared to wild type.,Z Gong 2022,2022,4 genes,Gong-2022-Two Magnaporthe appressoria-specific,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20154,PHI:123069,UniProt,I1RCU4,GenBank,CEF73558,,,PH-1,FgPMA1 (FGSG_01425),chromosome 1,,,Myosin-5; Bmh2,UniProt: I1RCT2; GenBank: SCB64236; UniProt: I1RCD4; GenBank: CEF73336,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; coleoptile; leaf,plasma membrane ATPase,,,,reduced virulence,,,,,,reduced; aberrant,reduced,reduced,reduced,no,NaCl; KCl; congo red; SDS; CaCl2; sorbitol; phenamacril,NaCl: CHEBI:26710; KCl: CHEBI:32588; congo red: CHEBI:34653; SDS: CHEBI:8984; CaCl2: CHEBI:3312; sorbitol: CHEBI:30911; phenamacril: CAS:3336-69-4,,,,,gene deletion: full; gene complementation,,,NN,34921490,PubMed,10.1111/mpp.13173,Mol Plant Pathol. 2022 Apr;23(4):489-502,mgzhou@njau.edu.cn,"The FgPMA1deletion mutant (ΔFgPMA1), but not FgPMA2 deletion mutant (ΔFgPMA2), was impaired in vegetative growth, pathogenicity, and sexual and asexual development. Co-immunoprecipitation confirmed that FgPMA1, FgMyo-5, and FgBmh2 (a 14-3-3 protein) form a complex to regulate the sensitivity to phenamacril and biological functions.",L Wu 2022,2022,2 genes,Wu-2021-The plasma membrane H(+) -ATPase FgPMA,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20155,PHI:123070,UniProt,I1RVQ6,GenBank,XP_011320444,,,PH-1; NRRL 31084,FgPMA2 (FGSG_08343),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; coleoptile; leaf,plasma membrane ATPase,,,,unaffected pathogenicity,,,,,,wild type,wild type,wild type,wild type,no,NaCl; KCl; congo red; SDS; CaCl2; sorbitol; phenamacril,NaCl: CHEBI:26710; KCl: CHEBI:32588; congo red: CHEBI:34653; SDS: CHEBI:8984; CaCl2: CHEBI:3312; sorbitol: CHEBI:30911; phenamacril: CAS:3336-69-4,,,,,gene deletion: full; gene complementation,,,NN,34921490,PubMed,10.1111/mpp.13173,Mol Plant Pathol. 2022 Apr;23(4):489-502,mgzhou@njau.edu.cn,"The FgPMA2 deletion mutant (ΔFgPMA2), was unimpaired in vegetative growth, pathogenicity, and sexual and asexual development of the pathogen.",L Wu 2022,2022,2 genes,Wu-2021-The plasma membrane H(+) -ATPase FgPMA,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20156,PHI:123071,UniProt,Q5AJ82,GenBank,Q5AJ82,,,SC5314,END3,chromosome 3,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,primates,9606,Homo sapiens (related: human),VK2/E6E7 cell line,,,VK-2/E6E7 cell,actin cytoskeleton-regulatory complex protein,,,,reduced virulence,,,,yes,,,,wild type,,no,SDS; calcofluor white; Congo red; caspofungin; amphotericin B; fluconazole; KCl; NaCl; LiCl,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; caspofungin: CHEBI:474180; amphotericin B: CHEBI:2682; fluconazole: CHEBI:46081; KCl: CHEBI:32588; NaCl: CHEBI:26710; LiCl: CHEBI:48607,,,,,gene deletion: full; gene complementation,,,NN,35234488,PubMed,10.1128/spectrum.01880-21,Microbiol Spectr. 2022 Apr 27;10(2):e0188021,samuel.a.lee@dartmouth.edu,"While in vitro growth, cell morphology, and vacuoles appeared normal, the END3 mutant was impaired in actin patch formation, filamentous growth, biofilm formation, cell wall integrity, and extracellular protease secretion. In in vitro keratinocyte infection model, the null mutant displayed reduced damage of mammalian adhesion zippers and host cell death.",C Rollenhagen 2022,2022,1 gene,Rollenhagen-2022-Candida albicans END3 Mediate,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20157,PHI:123072,UniProt,W7M843,GenBank,EWG43755,,,7600,FvATG4 (FVEG_05096),chromosome 4,,,FvATG8 (FVEG_11401),UniProt: W7MMQ7; GenBank: EWG52773,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,stem; kernel,cysteine protease,,,,reduced virulence,,,,yes,,wild type,reduced,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35443859,PubMed,10.1080/21505594.2022.2066611,Virulence. 2022 Dec;13(1):764-780,wendeliu@126.com,"The F. verticillioides deletion mutants ΔFvAtg4 and ΔFvAtg8 were impaired in autophagosome formation, aerial hyphal formation, sexual growth, lipid turnover, pigmentation and fungal virulence.",Y Wang 2022,2022,2 genes,Wang-2022-The autophagy-related proteins FvAtg,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20158,PHI:123073,UniProt,W7MMQ7,GenBank,EWG52773,,,7600,FvATG8 (FVEG_11401),chromosome 7,,,FvATG4 (FVEG_05096),UniProt: W7M843; GenBank: EWG43755,,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,stem; kernel,autophagy-related protein,,,,reduced virulence,,,,yes,,wild type,reduced,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35443859,PubMed,10.1080/21505594.2022.2066611,Virulence. 2022 Dec;13(1):764-780,wendeliu@126.com,"The F. verticillioides deletion mutants ΔFvAtg4 and ΔFvAtg8 were impaired in autophagosome formation, aerial hyphal formation, sexual growth, lipid turnover, pigmentation and fungal virulence.",Y Wang 2022,2022,2 genes,Wang-2022-The autophagy-related proteins FvAtg,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20159,PHI:123072,UniProt,W7M843,GenBank,EWG43755,,,7600,FvATG4 (FVEG_05096),chromosome 4,,,,,PHI:123073,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,stem; kernel,cysteine protease,,,,reduced virulence,,,,yes,,wild type,reduced,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35443859,PubMed,10.1080/21505594.2022.2066611,Virulence. 2022 Dec;13(1):764-780,wendeliu@126.com,"The F. verticillioides double deletion mutants ΔFvAtg4 and ΔFvAtg8 were impaired in autophagosome formation, aerial hyphal formation, sexual growth, lipid turnover, pigmentation and fungal virulence.",Y Wang 2022,2022,2 genes,Wang-2022-The autophagy-related proteins FvAtg,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20160,PHI:123073,UniProt,W7MMQ7,GenBank,EWG52773,,,7600,FvATG8 (FVEG_11401),chromosome 7,,,,,PHI:123072,117187,Fusarium verticillioides,334819,7600,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,stem; kernel,autophagy-related protein,,,,reduced virulence,,,,yes,,wild type,reduced,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35443859,PubMed,10.1080/21505594.2022.2066611,Virulence. 2022 Dec;13(1):764-780,wendeliu@126.com,"The F. verticillioides double deletion mutants ΔFvAtg4 and ΔFvAtg8 were impaired in autophagosome formation, aerial hyphal formation, sexual growth, lipid turnover, pigmentation and fungal virulence.",Y Wang 2022,2022,2 genes,Wang-2022-The autophagy-related proteins FvAtg,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20161,PHI:123074,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,140285,chiA (STM14_0022),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelial cell,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35482710,PubMed,10.1371/journal.ppat.1010407,PLoS Pathog. 2022 Apr 28;18(4):e1010407,dipa@iisc.ac.in,chiA deletion rendered the bacteria less invasive and hyperproliferative in epithelial cells.,K Chandra 2022,2022,2 genes,Chandra-2022-GH18 family glycoside hydrolase C,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20162,PHI:123075,UniProt,Q8Z9Q6,GenBank,AAO67752,,,Ty2,chiA (STY0018),,,,,,,28901,Salmonella enterica,90370,serovar Typhi strain CT18,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelial cell,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35482710,PubMed,10.1371/journal.ppat.1010407,PLoS Pathog. 2022 Apr 28;18(4):e1010407,dipa@iisc.ac.in,chiA deletion rendered the bacteria less invasive and hyperproliferative in epithelial cells.,K Chandra 2022,2022,2 genes,Chandra-2022-GH18 family glycoside hydrolase C,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20163,PHI:123075,UniProt,Q8Z9Q6,GenBank,AAO67752,,,Ty2,chiA (STY0018),,,,,,,28901,Salmonella enterica,90370,serovar Typhi strain CT18,salmonellosis,primates,9606,Homo sapiens (related: human),U-937 cell line,,,macrophage,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35482710,PubMed,10.1371/journal.ppat.1010407,PLoS Pathog. 2022 Apr 28;18(4):e1010407,dipa@iisc.ac.in,chiA deletion rendered the bacteria less invasive and hyperproliferative in U937 monocyte,K Chandra 2022,2022,2 genes,Chandra-2022-GH18 family glycoside hydrolase C,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20164,PHI:123074,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,140285,chiA (STM14_0022),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),U-937 cell line,,,macrophage,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35482710,PubMed,10.1371/journal.ppat.1010407,PLoS Pathog. 2022 Apr 28;18(4):e1010407,dipa@iisc.ac.in,chiA deletion rendered the bacteria less invasive and hyperproliferative in U937 monocyte,K Chandra 2022,2022,2 genes,Chandra-2022-GH18 family glycoside hydrolase C,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20165,PHI:123074,UniProt,A0A0F6AWD8,GenBank,ACY86559,,,140285,chiA (STM14_0022),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; spleen; mesenteric lymph node; Peyer's gland,putative exochitinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35482710,PubMed,10.1371/journal.ppat.1010407,PLoS Pathog. 2022 Apr 28;18(4):e1010407,dipa@iisc.ac.in,The ΔchiA infected animals showed enhanced survival than the WT infected cohort. ΔchiA mutant infected animals showed les sbacterial burden in each organ and body weight reduction than the WT infected animals.,K Chandra 2022,2022,2 genes,Chandra-2022-GH18 family glycoside hydrolase C,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20166,PHI:123076,UniProt,G3E7K6,GenBank,AEM65935,,,Cmm_MKH,Pat-1,,Tn::pat-1Cm; ΔpCM2; S223A; H96A; D122A; S231A; C189A; C199A,,,,,28447,Clavibacter michiganensis,,LMG 7333,bacterial wilt; bacterial canker,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Betatini,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene deletion: full; gene deletion: partial; gene complementation,,,NN,35432427,PubMed,10.3389/fpls.2022.888290,Front Plant Sci. 2022 Mar 30;13:888290,co35@khu.ac.kr,"The pat-1Cm mutant Tn::pat-1Cmstrain or 7333ΔpCM2 impaired to cause wilting, but still caused canker symptom in tomato. The Tn::pat-1Cm mutant strain carrying all alanine substitutions except for at S223A failed to restore the mutant's abilities to cause wilting in tomato.",I S Hwang 2022,2022,1 gene,Hwang-2022-An Apoplastic Effector Pat-1(Cm) of,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20167,PHI:123076,UniProt,G3E7K6,GenBank,AEM65935,,,Cmm_MKH,Pat-1,,Tn::pat-1Cm; ΔpCM2; S223A; H96A; D122A; S231A; C189A; C199A,,,,,28447,Clavibacter michiganensis,,LMG 7333,bacterial wilt; bacterial canker,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Samsun,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; gene deletion: full; gene complementation,,,NN,35432427,PubMed,10.3389/fpls.2022.888290,Front Plant Sci. 2022 Mar 30;13:888290,co35@khu.ac.kr,"Hypersensitive response was not induced by the mutant strains, Tn::pat-1Cm and 7333ΔpCM2 in nonhost plant Nicotiana tabacum. The Tn::pat-1Cm mutant strain carrying all alanine substitutions except for at S223A failed to restore the mutant's abilities to elicit HR in N. tabacum.",I S Hwang 2022,2022,1 gene,Hwang-2022-An Apoplastic Effector Pat-1(Cm) of,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20168,PHI:123077,UniProt,G4N534,GenBank,EHA52945,,,70-15,MoPtc1,chromosome 3,,,MoMkk1,GenBank: EHA50760,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,protein phosphatase 2C,,,cell wall integrity (CWI) pathway,reduced virulence,,yes,yes,,low disease severity,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35506374,PubMed,10.1111/mpp.13225,Mol Plant Pathol. 2022 May 4,zhgzhang@njau.edu.cn,CWI signalling in M. oryzae is a highly coordinated regulatory mechanism vital for stress response and pathogenicity,Y Cai 2021,2021,2 genes,Cai-2022-Homeostasis of cell wall integrity pa,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20169,PHI:123078,UniProt,G4MZ06,GenBank,EHA54473,,,70-15,MoPtc2,chromosome 2,,,MoMkk1,GenBank: EHA50760,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,protein phosphatase 2C Ptc2,,,cell wall integrity (CWI) pathway,reduced virulence,,yes,yes,,low disease severity,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35506374,PubMed,10.1111/mpp.13225,Mol Plant Pathol. 2022 May 4,zhgzhang@njau.edu.cn,CWI signalling in M. oryzae is a highly coordinated regulatory mechanism vital for stress response and pathogenicity,Y Cai 2021,2021,2 genes,Cai-2022-Homeostasis of cell wall integrity pa,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20170,PHI:123077,UniProt,G4N534,GenBank,EHA52945,,,70-15,MoPtc1,chromosome 3,,,MoMkk1,GenBank: EHA50760,PHI:2,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,protein phosphatase 2C,,,cell wall integrity (CWI) pathway,reduced virulence,,yes,yes,,low disease severity,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35506374,PubMed,10.1111/mpp.13225,Mol Plant Pathol. 2022 May 4,zhgzhang@njau.edu.cn,CWI signalling in M. oryzae is a highly coordinated regulatory mechanism vital for stress response and pathogenicity,Y Cai 2021,2021,2 genes,Cai-2022-Homeostasis of cell wall integrity pa,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20171,PHI:123078,UniProt,G4MZ06,GenBank,EHA54473,,,70-15,MoPtc2,chromosome 2,,,MoMkk1,GenBank: EHA50760,PHI:1,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,protein phosphatase 2C Ptc2,,,cell wall integrity (CWI) pathway,reduced virulence,,yes,yes,,low disease severity,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35506374,PubMed,10.1111/mpp.13225,Mol Plant Pathol. 2022 May 4,zhgzhang@njau.edu.cn,CWI signalling in M. oryzae is a highly coordinated regulatory mechanism vital for stress response and pathogenicity,Y Cai 2021,2021,2 genes,Cai-2022-Homeostasis of cell wall integrity pa,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20172,PHI:123079,UniProt,A0A2N6P0D9,GenBank,PMB72982,,,JEF-007,Cdc42,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,cell division control protein 42 homolog,,,pyruvate metabolism pathway; TCA pathway,reduced virulence,,,,,,reduced,,reduced,defective,no,,,,,,,gene mutation; gene complementation,,,NN,35448625,PubMed,10.3390/jof8040394,J Fungi (Basel). 2022 Apr 12;8(4):394,wangdonghuang_2022@163.com,Essential role of Cdc42 was found not only in the fungal cell cycle/division but also the fungal insect-pathogenic lifestyle,Y Guan 2022,2022,1 gene,Guan-2022-Unveiling a Novel Role of Cdc42 in P,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20173,PHI:123080,UniProt,A0A060VRS3,GenBank,MTX48026,,,KP_46186,qseB,,,,,,,573,Klebsiella pneumoniae,,ST258,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,two-component system response regulator QseB,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35464966,PubMed,10.3389/fmicb.2022.817494,Front Microbiol. 2022 Apr 6;13:817494,hong_du@126.com,Deletion of qseC increased biofilm formation and serum resistance of ATCC43816,J Lv 2022,2022,2 genes,Lv-2022-The Role of the Two-Component QseBC Si,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20174,PHI:123081,UniProt,A0A331M0L4,GenBank,SSH68262,,,4300STDY6470518,qseC,,,,,,,573,Klebsiella pneumoniae,,ST258,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,sensor protein QseC,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35464966,PubMed,10.3389/fmicb.2022.817494,Front Microbiol. 2022 Apr 6;13:817494,hong_du@126.com,Deletion of qseC increased biofilm formation and serum resistance of ATCC43816,J Lv 2022,2022,2 genes,Lv-2022-The Role of the Two-Component QseBC Si,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20175,PHI:123080,UniProt,A0A060VRS3,GenBank,MTX48026,,,KP_46186,qseB,,,,,,PHI:123081,573,Klebsiella pneumoniae,,ST258,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,two-component system response regulator QseB,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35464966,PubMed,10.3389/fmicb.2022.817494,Front Microbiol. 2022 Apr 6;13:817494,hong_du@126.com,Deletion of qseC increased biofilm formation and serum resistance of ATCC43816,J Lv 2022,2022,2 genes,Lv-2022-The Role of the Two-Component QseBC Si,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20176,PHI:123081,UniProt,A0A331M0L4,GenBank,SSH68262,,,4300STDY6470518,qseC,,,,,,PHI:123080,573,Klebsiella pneumoniae,,ST258,pneumonia,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,sensor protein QseC,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35464966,PubMed,10.3389/fmicb.2022.817494,Front Microbiol. 2022 Apr 6;13:817494,hong_du@126.com,Deletion of qseC increased biofilm formation and serum resistance of ATCC43816,J Lv 2022,2022,2 genes,Lv-2022-The Role of the Two-Component QseBC Si,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20177,PHI:123082,UniProt,F5HEE7,GenBank,CAL59409,,,PG2,VpmaU,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,mammary gland,variable surface lipoprotein U (VpmaUprecursor),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35456865,PubMed,10.3390/microorganisms10040815,Microorganisms. 2022 Apr 14;10(4):815,andi.dagn@gmx.at,"Thorough bacteriological, pathological and clinical examinations were performed, including assessment of milk quality, quantity and somatic cell counts. Tissue: udder",R Chopra-Dewasthaly 2022,2022,6 genes,Chopra-Dewastha-2022-Sheep Infection Trials wi,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20178,PHI:123083,UniProt,F5HI53,GenBank,CAL59405,,,PG2,VpmaV,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,mammary gland,variable surface lipoprotein V (VpmaVprecursor),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35456865,PubMed,10.3390/microorganisms10040815,Microorganisms. 2022 Apr 14;10(4):815,andi.dagn@gmx.at,"Thorough bacteriological, pathological and clinical examinations were performed, including assessment of milk quality, quantity and somatic cell counts. Tissue: udder",R Chopra-Dewasthaly 2022,2022,6 genes,Chopra-Dewastha-2022-Sheep Infection Trials wi,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20179,PHI:123084,UniProt,F5HES2,GenBank,CAL59406,,,PG2,VpmaW,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,mammary gland,variable surface lipoprotein W (VpmaWprecursor),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35456865,PubMed,10.3390/microorganisms10040815,Microorganisms. 2022 Apr 14;10(4):815,andi.dagn@gmx.at,"Thorough bacteriological, pathological and clinical examinations were performed, including assessment of milk quality, quantity and somatic cell counts. Tissue: udder",R Chopra-Dewasthaly 2022,2022,6 genes,Chopra-Dewastha-2022-Sheep Infection Trials wi,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20180,PHI:123085,UniProt,F5HIG3,GenBank,CAL59407,,,PG2,VpmaX,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,mammary gland,variable surface lipoprotein A (VpmaXprecusor),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35456865,PubMed,10.3390/microorganisms10040815,Microorganisms. 2022 Apr 14;10(4):815,andi.dagn@gmx.at,"Thorough bacteriological, pathological and clinical examinations were performed, including assessment of milk quality, quantity and somatic cell counts. Tissue: udder",R Chopra-Dewasthaly 2022,2022,6 genes,Chopra-Dewastha-2022-Sheep Infection Trials wi,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20181,PHI:123086,UniProt,F5HDB1,GenBank,CAL59408,,,PG2,VpmaY,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,mammary gland,variable surface lipoprotein Y (VpmaYprecursor),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35456865,PubMed,10.3390/microorganisms10040815,Microorganisms. 2022 Apr 14;10(4):815,andi.dagn@gmx.at,"Thorough bacteriological, pathological and clinical examinations were performed, including assessment of milk quality, quantity and somatic cell counts. Tissue: udder",R Chopra-Dewasthaly 2022,2022,6 genes,Chopra-Dewastha-2022-Sheep Infection Trials wi,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20182,PHI:123087,UniProt,F5HE41,GenBank,CAL59410,,,PG2,VpmaZ,,,,,,,2110,Mycoplasmopsis agalactiae,347257,PG2,contagious agalactia,even-toed ungulates,9940,Ovis aries (related: sheep),,,,mammary gland,variable surface lipoprotein D (VpmaZprecursor),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35456865,PubMed,10.3390/microorganisms10040815,Microorganisms. 2022 Apr 14;10(4):815,andi.dagn@gmx.at,"Thorough bacteriological, pathological and clinical examinations were performed, including assessment of milk quality, quantity and somatic cell counts. Tissue: udder",R Chopra-Dewasthaly 2022,2022,6 genes,Chopra-Dewastha-2022-Sheep Infection Trials wi,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20183,PHI:123088,UniProt,Q93C69,GenBank,AF411962_3,,,,RpfF,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Taichung Native-1,,,leaf,diffusible signal factor synthase,,,fatty acid synthesis pathway,reduced virulence,,,,,reduced lesion length,,,,,no,SDS; tween 20 triton X-100,"SDS: CHEBI:8984, 20; tween: CHEBI:53424; Triton X-100: CHEBI:9750",,,,,gene deletion: full; gene complementation,,,NN,34704368,PubMed,10.1111/mpp.13148,Mol Plant Pathol. 2022 Jan;23(1):118-132,subhadeep@cdfd.org.in,X. oryzae pv. oryzae RpfF is involved in the maintenance of membrane integrity by playing a regulatory role in the fatty acid synthesis pathway,P Singh 2022,2022,2 genes,Singh-2021-The diffusible signal factor syntha,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20184,PHI:123089,UniProt,Q6R4Z3,GenBank,AAR99586,,,,xpsE,,,,,,,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Taichung Native-1,,,leaf,type II secretion system protein E,,,fatty acid synthesis pathway,reduced virulence,,,,,reduced lesion length,,,,,no,SDS; tween 20 triton X-100,"SDS: CHEBI:8984, 20; tween: CHEBI:53424; Triton X-100: CHEBI:9750",,,,,gene deletion: full,,,NN,34704368,PubMed,10.1111/mpp.13148,Mol Plant Pathol. 2022 Jan;23(1):118-132,subhadeep@cdfd.org.in,X. oryzae pv. oryzae RpfF is involved in the maintenance of membrane integrity by playing a regulatory role in the fatty acid synthesis pathway,P Singh 2022,2022,2 genes,Singh-2021-The diffusible signal factor syntha,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20185,PHI:123088,UniProt,Q93C69,GenBank,AF411962_3,,,,RpfF,,,,,,PHI:123089,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Taichung Native-1,,,leaf,diffusible signal factor synthase,,,fatty acid synthesis pathway,reduced virulence,,,,,reduced lesion length,,,,,no,SDS; tween 20 triton X-100,"SDS: CHEBI:8984, 20; tween: CHEBI:53424; Triton X-100: CHEBI:9750",,,,,gene deletion: full; gene complementation,,,NN,34704368,PubMed,10.1111/mpp.13148,Mol Plant Pathol. 2022 Jan;23(1):118-132,subhadeep@cdfd.org.in,X. oryzae pv. oryzae RpfF is involved in the maintenance of membrane integrity by playing a regulatory role in the fatty acid synthesis pathway,P Singh 2022,2022,2 genes,Singh-2021-The diffusible signal factor syntha,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20186,PHI:123089,UniProt,Q6R4Z3,GenBank,AAR99586,,,,xpsE,,,,,,PHI:123088,347,Xanthomonas oryzae,64187,pv. oryzae strain BXO43,blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Taichung Native-1,,,leaf,type II secretion system protein E,,,fatty acid synthesis pathway,reduced virulence,,,,,reduced lesion length,,,,,no,SDS; tween 20 triton X-100,"SDS: CHEBI:8984, 20; tween: CHEBI:53424; Triton X-100: CHEBI:9750",,,,,gene deletion: full; gene complementation,,,NN,34704368,PubMed,10.1111/mpp.13148,Mol Plant Pathol. 2022 Jan;23(1):118-132,subhadeep@cdfd.org.in,X. oryzae pv. oryzae RpfF is involved in the maintenance of membrane integrity by playing a regulatory role in the fatty acid synthesis pathway,P Singh 2022,2022,2 genes,Singh-2021-The diffusible signal factor syntha,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20187,PHI:123090,UniProt,B8N4V2,GenBank,EED54559,,,NRRL3357,bZIP1 (AFLA_018110),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,"bZip transcription factor, putative",,,,unaffected pathogenicity,,,,,,increased,,reduced,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20188,PHI:123091,UniProt,B8NE66,GenBank,EED51534,,,NRRL3357,bZIP2 (AFLA_057970),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,"bZip transcription factor, putative",,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20189,PHI:123092,UniProt,B8MXR3,GenBank,EED57155,,,NRRL3357,bZIP4 (AFLA_078500),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,"bZip transcription factor, putative",,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20190,PHI:123093,UniProt,B8MW91,GenBank,EED58082,,,NRRL3357,bZIP5 (AFLA_087810),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,"bZip transcription factor, putative",,,,unaffected pathogenicity,,,,,,reduced,,wild type,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20191,PHI:123094,UniProt,B8NX53,GenBank,EED46011,,,NRRL3357,bZIP6 (AFLA_122410),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,bZip domain-containing protein,,,,increased virulence (hypervirulence),,,,,,wild type,,wild type,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20192,PHI:123095,UniProt,B8NNN3,GenBank,EED48711,,,NRRL3357,AP1 (AFLA_129340),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,AP-1-like transcription factor yap1,,,,reduced virulence,,,,,,wild type,,wild type,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20193,PHI:123096,UniProt,B8N3Q0,GenBank,EED55862,,,NRRL3357,AtfA (AFLA_031340),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,"bZip transcription factor (AtfA), putative",,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20194,PHI:123097,UniProt,B8NLU5,GenBank,EED49320,,,NRRL3357,AtfB (AFLA_094010),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,basic leucine zipper (bZip) transcription factor atfB,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20195,PHI:123098,UniProt,B8NSS4,GenBank,EED46972,,,NRRL3357,CpcA (AFLA_050250),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,bZip transcription factor CpcA,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20196,PHI:123099,UniProt,B8NFS7,GenBank,EED50594,,,NRRL3357,Fcr3 (AFLA_133560),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,"bZip transcription factor (Fcr3), putative",,,,reduced virulence,,,,,,reduced,,wild type,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20197,PHI:123100,UniProt,B8NQJ0,GenBank,EED48028,,,NRRL3357,HapX (AFLA_006720),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,bZip transcription factor HapX,,,,unaffected pathogenicity,,,,,,reduced,,wild type,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20198,PHI:123101,UniProt,B8NUN6,GenBank,EED46425,,,NRRL3357,JlbA (AFLA_100890),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,"bZip transcription factor JlbA, putative",,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20199,PHI:123102,UniProt,B8MZ21,GenBank,EED57613,,,NRRL3357,LziP (AFLA_083100),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,"bZip transcription factor (LZIP), putative",,,,reduced virulence,,,,,,reduced,,wild type,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20200,PHI:123103,UniProt,B8N3U5,GenBank,EED55907,,,NRRL3357,MeaB (AFLA_031790),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,"bZip transcription factor (MeaB), putative",,,,unaffected pathogenicity,,,,,,reduced,,wild type,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20201,PHI:123104,UniProt,B8NA49,GenBank,EED53968,,,NRRL3357,MetR (AFLA_113450),,,,,,,5059,Aspergillus flavus,332952,NRRL 3357,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,"bZip transcription factor (MetR), putative",,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white; H2O2; sorbitol,calcofluor white: CHEBI:50011; H2O2: CHEBI:16240; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,35448587,PubMed,10.3390/jof8040356,J Fungi (Basel). 2022 Mar 30;8(4):356,zhaoqianqian202203@163.com,"The mutants of five bZIPs did not produce sclerotia, including DbZIP1, DbZIP4, DAtfA, DMeaB andDMetR",Q Zhao 2022,2022,15 genes,Zhao-2022-Systematic Characterization of bZIP,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20202,PHI:123105,UniProt,Q8F0K3,GenBank,AAN50688,,,56601,LA3490 (NP_713670.1),chromosome 1,"LA3490 coding sequence (NP_713670.1) minus the predicted signal peptide (i.e., corresponding to nucleotide positions 57-1,917 bp)",,,,,173,Leptospira interrogans,,serovar Lai strain 56601,leptospirosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,virulence-modifying (VM) proteins,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: partial,,,NN,35422779,PubMed,10.3389/fmicb.2022.859680,Front Microbiol. 2022 Mar 29;13:859680,joseph.vinetz@yale.edu,"t3490 alone was sufficient for binding, both to immobilized asialofetuin and to the HeLa cell surface but was neither internalized nor cytotoxic. Treatment of HeLa cells with rLA3490 led to cytoskeleton disassembly, caspase-3 activation, and nuclear fragmentation, and was rapidly cytolethal",R Chaurasia 2022,2022,1 gene,Chaurasia-2022-Pathogenic Leptospira Evolved a,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20203,PHI:123105,UniProt,Q8F0K3,GenBank,AAN50688,,,56601,LA3490 (NP_713670.1),chromosome 1,LA3490 coding sequence (NP_713670.1) minus N-terminal truncation inclusive of positions 40-174 bp and encompassing the Phyre2-predicted ricin B-like lectin subdomain linked to mCherry (AST15061.1) via a glycine-serine hinge (GGGGSGGGGSGGGGS),,,,,173,Leptospira interrogans,,serovar Lai strain 56601,leptospirosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,HeLa cell,virulence-modifying (VM) proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: partial,,,NN,35422779,PubMed,10.3389/fmicb.2022.859680,Front Microbiol. 2022 Mar 29;13:859680,joseph.vinetz@yale.edu,"t3490 alone was sufficient for binding, both to immobilized asialofetuin and to the HeLa cell surface but was neither internalized nor cytotoxic. Treatment of HeLa cells with rLA3490 led to cytoskeleton disassembly, caspase-3 activation, and nuclear fragmentation, and was rapidly cytolethal",R Chaurasia 2022,2022,1 gene,Chaurasia-2022-Pathogenic Leptospira Evolved a,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20204,PHI:123106,UniProt,X0KJP3,GenBank,EXM08967,,,54006,FoQDE2 (FOIG_01986),,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,argonaute coding gene,,,milRNA biosynthetic pathway,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20205,PHI:123107,UniProt,A0A559KTQ3,,,,,,FoDCL1,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,dicer coding gene,,,milRNA biosynthetic pathway,unaffected pathogenicity,,,,,tissue necrosis,reduced,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20206,PHI:123108,,no data found,,,,,,FoDCL2,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,dicer coding gene,,,milRNA biosynthetic pathway,unaffected pathogenicity,,,,,tissue necrosis,wild type,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20207,PHI:123109,UniProt,X0KJP3,GenBank,EXM08967,,,54006,FoQDE2 (FOIG_01986),,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),,,,corm,argonaute coding gene,,,milRNA biosynthetic pathway,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt. Tissue 'corm of seedlings'.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20208,PHI:123110,UniProt,A0A559KTQ3,,,,,,FoDCL1,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),,,,corm,dicer coding gene,,,milRNA biosynthetic pathway,unaffected pathogenicity,,,,,vascular discoloration,reduced,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt. Tissue 'corm of seedlings'.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20209,PHI:123111,,no data found,,,,,,FoDCL2,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),,,,corm,dicer coding gene,,,milRNA biosynthetic pathway,reduced virulence,,,,,low disease severity,wild type,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt. Tissue 'corm of seedlings'.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20210,PHI:123112,,no data found,,,,,,milR-87,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,microRNA-like RNAs,,,milRNA biosynthetic pathway,reduced virulence,,,,,slighter necrosis,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20211,PHI:123112,,no data found,,,,,,milR-87,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,microRNA-like RNAs,,,milRNA biosynthetic pathway,increased virulence (hypervirulence),,,,,increased necrosis,increased,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20212,PHI:123113,,no data found,,,,,,milR-87,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),,,,corm,microRNA-like RNAs,,,milRNA biosynthetic pathway,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt. Tissue 'corm of seedlings'.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20213,PHI:123113,,no data found,,,,,,milR-87,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),,,,corm,microRNA-like RNAs,,,milRNA biosynthetic pathway,increased virulence (hypervirulence),,,,,brown discoloration,increased,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt. Tissue 'corm of seedlings'.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20214,PHI:123114,UniProt,X0ISP3,GenBank,EXL91923,,,54006,FOIG_15013,,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4 strain XJZ2,vascular wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),,,,corm,glyco_hydro_79C domain-containing protein,,,milRNA biosynthetic pathway,increased virulence (hypervirulence),,,,,increased necrosis,increased,,increased,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35512028,PubMed,10.1371/journal.ppat.1010157,,PLoS Pathog. 2022 May 5;18(5):e1010157,The identified pathogenicity-involved milRNA provides an active target for developing novel and efficient biocontrol agents against Banana Fusarium wilt. Tissue 'corm of seedlings'.,M Li 2022,2022,5 genes,Li-2022-FoQDE2-dependent milRNA promotes Fusar,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20215,PHI:123115,UniProt,Q4X0A4,GenBank,EAL93711,,,Af293,Atg20 (XP_755749.2),chromosome 2,,,Atg24 (XP_751536.10),GenBank: EAL89498,,746128,Aspergillus fumigatus,,akuBKU80,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,"autophagy protein Atg20, putative",,,autophagy pathway,reduced virulence,,,,,,,,reduced,,no,caspofungin,caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,NN,35448585,PubMed,10.3390/jof8040354,J Fungi (Basel). 2022 Mar 30;8(4):354,keats.shwab@duke.edu,PKA regulates the autophagy pathway,E K Shwab 2022,2022,1 gene,Shwab-2022-Protein Kinase A Regulates Autophag,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20216,PHI:123116,UniProt,A0A1D9QD76,,,,,,SsPINE1-1,,,,AtPGIP1,UniProt: Q9M5J9,,5180,Sclerotinia sclerotiorum,,WMA1,white mold,eudicots,3888,Pisum sativum (related: Pea),cv. Guido,,,leaf,PGIP-INactivating effector,,,,reduced virulence,,,,,reduced lesions,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20217,PHI:123117,,no data found,,,,,,SsPINE1-7,,,,AtPGIP1,UniProt: Q9M5J9,,5180,Sclerotinia sclerotiorum,,WMA1,white mold,eudicots,3888,Pisum sativum (related: Pea),cv. Guido,,,leaf,PGIP-INactivating effector,,,,reduced virulence,,,,,reduced lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20218,PHI:123118,UniProt,Q12708,,,,,,SsPG1-1,,,,AtPGIP1,UniProt: Q9M5J9,,5180,Sclerotinia sclerotiorum,,WMA1,white mold,eudicots,3888,Pisum sativum (related: Pea),cv. Guido,,,leaf,PG-inhibiting proteins,,,,reduced virulence,,,,,reduced lesions,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20219,PHI:123119,,no data found,,,,,,SsPG1-3,,,,AtPGIP1,UniProt: Q9M5J9,,5180,Sclerotinia sclerotiorum,,WMA1,white mold,eudicots,3888,Pisum sativum (related: Pea),cv. Guido,,,leaf,PG-inhibiting proteins,,,,reduced virulence,,,,,reduced lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20220,PHI:123120,,no data found,,,,,,SsPINE1-7,,,,AtPGIP1,UniProt: Q9M5J9,,5180,Sclerotinia sclerotiorum,,WMA1,white mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,PGIP-INactivating effector,,,,reduced virulence,,,,,reduced lesions,,,,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20221,PHI:123121,,no data found,,,,,,SsPG1-2,,,,AtPGIP1,UniProt: Q9M5J9,,5180,Sclerotinia sclerotiorum,,WMA1,white mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,PG-inhibiting proteins,,,,reduced virulence,,,,,reduced lesions,,,,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20222,PHI:123122,,no data found,,,,,,SsPINE1-7,,,,AtPGIP1,UniProt: Q9M5J9,,5180,Sclerotinia sclerotiorum,,WMA1,white mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),35S::SsPINE1,,,leaf,PGIP-INactivating effector,,,,increased virulence (hypervirulence),,,,,increased lesions,,,,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20223,PHI:123123,,no data found,,,,,,SsPG1-2,,,,AtPGIP1,UniProt: Q9M5J9,,5180,Sclerotinia sclerotiorum,,WMA1,white mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),35S::SsPINE1,,,leaf,PG-inhibiting proteins,,,,increased virulence (hypervirulence),,,,,increased lesions,,,,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20224,PHI:123124,,no data found,,,,,,SsPINE1-7,,,,AtPGIP1,UniProt: Q9M5J9,,5180,Sclerotinia sclerotiorum,,WMA1,white mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),35S::AtPGIP1,,,leaf,PGIP-INactivating effector,,,,reduced virulence,,,,,reduced lesions,,,,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20225,PHI:123125,,no data found,,,,,,SsPG1-2,,,,AtPGIP1,UniProt: Q9M5J9,,5180,Sclerotinia sclerotiorum,,WMA1,white mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),35S::AtPGIP1,,,leaf,PG-inhibiting proteins,,,,reduced virulence,,,,,reduced lesions,,,,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20226,PHI:123126,,no data found,,,,,,BcPINE1-3,,,,AtPGIP1,UniProt: Q9M5J9,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,PGIP-INactivating effector,,,,reduced virulence,,,,,reduced lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20227,PHI:123127,,no data found,,,,,,BcPINE1-6,,,,AtPGIP1,UniProt: Q9M5J9,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,PGIP-INactivating effector,,,,reduced virulence,,,,,reduced lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20228,PHI:123128,,no data found,,,,,,BcPINE1-3,,,,AtPGIP1,UniProt: Q9M5J9,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),35S::SsPINE1,,,leaf,PGIP-INactivating effector,,,,unaffected pathogenicity,,,,,increased lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20229,PHI:123129,,no data found,,,,,,BcPINE1-6,,,,AtPGIP1,UniProt: Q9M5J9,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),35S::SsPINE1,,,leaf,PGIP-INactivating effector,,,,unaffected pathogenicity,,,,,increased lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20230,PHI:123130,,no data found,,,,,,BcPINE1-3,,,,AtPGIP1,UniProt: Q9M5J9,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),35S::AtPGIP1,,,leaf,PGIP-INactivating effector,,,,reduced virulence,,,,,reduced lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20231,PHI:123131,,no data found,,,,,,BcPINE1-6,,,,AtPGIP1,UniProt: Q9M5J9,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),35S::AtPGIP1,,,leaf,PGIP-INactivating effector,,,,reduced virulence,,,,,reduced lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35468894,PubMed,10.1038/s41467-022-29788-2,Nat Commun. 2022 Apr 25;13(1):2213,weidong.chen@usda.gov,,W Wei 2022,2022,7 genes,Wei-2022-A fungal extracellular effector inact,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20232,PHI:123132,UniProt,Q46941,GenBank,AAB40493,,,K-12,yqeH,,,,,,,562,Escherichia coli,,APEC 40 serotype O18:K1,avian colibacillosis,birds,9031,Gallus gallus (related: chicken),UMNSAH/DF-1 cell line,,,embryo fibroblast cell line; blood; liver; spleen; kidney,transcriptional regulator YqeH,,,,reduced virulence,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35436977,PubMed,10.1186/s13567-022-01049-6,Vet Res. 2022 Apr 18;53(1):30,pxcpyq@sina.com,"The deletion of yqeH downregulated the transcript levels of several flagellum-, biofilm-, and virulence-related genes",L Yin 2022,2022,1 gene,Yin-2022-YqeH contributes to avian pathogenic,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20233,PHI:123133,UniProt,D0N2F7,GenBank,EEY68486,,,T30-4,PiAA17C (PITG_04949),,,,,,,4787,Phytophthora infestans,,88069,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Bintje,,,leaf,auxiliary activity 17,,,,reduced virulence,,,,,reduced lesions,,,,,no,ascorbic acid; pyrogallol; gallic acid,ascorbic acid: CHEBI:22652; pyrogallol: CHEBI:16164; gallic acid: CHEBI:30778,,,,,altered gene expression / gene regulation: silencing,,,NN,34385392,PubMed,10.1126/science.abj1342,Science. 2021 Aug 13;373(6556):774-779,federico.sabbadin@york.ac.uk,"LPMO-encoding genes are up-regulated early during infection and that the secreted enzymes oxidatively cleave the backbone of pectin, a charged polysaccharide in the plant cell wall",F Sabbadin 2022,2022,1 gene,Sabbadin-2021-Secreted pectin monooxygenases d,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20234,PHI:123134,UniProt,D0N2F7,GenBank,EEY68486,,,T30-4,PiAA17C (PITG_04949),,,,,,,4787,Phytophthora infestans,,3928A,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Maris Piper,,,leaf,auxiliary activity 17,,,,reduced virulence,,,,,reduced lesions,,,,,no,ascorbic acid; pyrogallol; gallic acid,ascorbic acid: CHEBI:22652; pyrogallol: CHEBI:16164; gallic acid: CHEBI:30778,,,,,altered gene expression / gene regulation: silencing,,,NN,34385392,PubMed,10.1126/science.abj1342,Science. 2021 Aug 13;373(6556):774-779,federico.sabbadin@york.ac.uk,"LPMO-encoding genes are up-regulated early during infection and that the secreted enzymes oxidatively cleave the backbone of pectin, a charged polysaccharide in the plant cell wall",F Sabbadin 2022,2022,1 gene,Sabbadin-2021-Secreted pectin monooxygenases d,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20235,PHI:123135,,no data found,,,,,,MOEITF1,,,,,,,318829,Magnaporthe oryzae,,98-06,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,early infection-induced transcription factor,,,,reduced virulence,,no,,,fewer and smaller lesions,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35430769,PubMed,10.1111/mpp.13224,Mol Plant Pathol. 2022 Apr 17,stefan@olssonstefan.com,"MOEITF1 and MOEITF2, were specifically up-regulated during the early infection process and each specifically controls the expression of a gene for an effector protein.",Y Cao 2022,2022,4 genes,Cao-2022-Characterization of two infection-ind,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20236,PHI:123136,,no data found,,,,,,MOEITF2,,,,,,,318829,Magnaporthe oryzae,,98-06,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,early infection-induced transcription factor,,,,reduced virulence,,no,,,fewer and smaller lesions,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35430769,PubMed,10.1111/mpp.13224,Mol Plant Pathol. 2022 Apr 17,stefan@olssonstefan.com,"MOEITF1 and MOEITF2, were specifically up-regulated during the early infection process and each specifically controls the expression of a gene for an effector protein.",Y Cao 2022,2022,4 genes,Cao-2022-Characterization of two infection-ind,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20237,PHI:123137,,no data found,,,,,,T2REP-1,,,,,,,318829,Magnaporthe oryzae,,98-06,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector protein,,,,reduced virulence,,,,,fewer and smaller lesions,,,,,no,,,,,,,gene mutation,,,NN,35430769,PubMed,10.1111/mpp.13224,Mol Plant Pathol. 2022 Apr 17,stefan@olssonstefan.com,"MOEITF1 and MOEITF2, were specifically up-regulated during the early infection process and each specifically controls the expression of a gene for an effector protein.",Y Cao 2022,2022,4 genes,Cao-2022-Characterization of two infection-ind,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20238,PHI:123138,,no data found,,,,,,T2REP-2,,,,,,,318829,Magnaporthe oryzae,,98-06,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector protein,,,,reduced virulence,,,,,fewer and smaller lesions,,,,,no,,,,,,,gene mutation,,,NN,35430769,PubMed,10.1111/mpp.13224,Mol Plant Pathol. 2022 Apr 17,stefan@olssonstefan.com,"MOEITF1 and MOEITF2, were specifically up-regulated during the early infection process and each specifically controls the expression of a gene for an effector protein.",Y Cao 2022,2022,4 genes,Cao-2022-Characterization of two infection-ind,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20239,PHI:123139,UniProt,A0A1R4AEC9,GenBank,FUFI01000021,,,SU60,PPAD,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),,,,gingival fibroblast,peptidilarginine deiminase,,,NF-kB and mitogen-activated protein kinase (MAPK) signaling pathways,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35432342,PubMed,10.3389/fimmu.2022.823685,Front Immunol. 2022 Apr 1;13:823685,aleksander.grabiec@uj.edu.pl,Both PPAD activity and fimbriae are important for TLR2-dependent cell responses to P. gingivalis infection,A Wielento 2022,2022,2 genes,Wielento-2022-TLR2 Activation by Porphyromonas,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20240,PHI:123140,UniProt,B2RH54,GenBank,POYFIMA2,,,ATCC 33277,FimA,,,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),,,,gingival fibroblast,major fimbrium subunit FimA type-1,,,NF-kB and mitogen-activated protein kinase (MAPK) signaling pathways,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35432342,PubMed,10.3389/fimmu.2022.823685,Front Immunol. 2022 Apr 1;13:823685,aleksander.grabiec@uj.edu.pl,Both PPAD activity and fimbriae are important for TLR2-dependent cell responses to P. gingivalis infection,A Wielento 2022,2022,2 genes,Wielento-2022-TLR2 Activation by Porphyromonas,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20241,PHI:123141,UniProt,A0A1R4AEC9,GenBank,FUFI01000021,,,SU60,PPAD,,C351A,,,,,837,Porphyromonas gingivalis,431947,ATCC 33277,periodontitis,primates,9606,Homo sapiens (related: human),,,,gingival fibroblast,peptidilarginine deiminase,,,NF-kB and mitogen-activated protein kinase (MAPK) signaling pathways,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35432342,PubMed,10.3389/fimmu.2022.823685,Front Immunol. 2022 Apr 1;13:823685,aleksander.grabiec@uj.edu.pl,Both PPAD activity and fimbriae are important for TLR2-dependent cell responses to P. gingivalis infection,A Wielento 2022,2022,2 genes,Wielento-2022-TLR2 Activation by Porphyromonas,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20242,PHI:123142,UniProt,P18177,GenBank,X53138,,,VPI 10463,TcdB,,,,,,,1496,Clostridioides difficile,,VPI10463,pseudomembranous colitis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,toxin B,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: purified protein,,,NN,35457076,PubMed,10.3390/ijms23084258,Int J Mol Sci. 2022 Apr 12;23(8):4258,stieglitz.florian@mh-hannover.de,RAS-mediated effect revealed that APOC3 expression was induced by TcdB and TcdBNXN and that RAS inhibition prohibited the expression of APOC3 upon TcdB and TcdBNXN treatment,F Stieglitz 2022,2022,1 gene,Stieglitz-2022-TcdB of Clostridioides difficil,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20243,PHI:123143,UniProt,P18177,GenBank,X53138,,,VPI 10463,TcdB,,NXN,,,,,1496,Clostridioides difficile,,VPI10463,pseudomembranous colitis,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,toxin B,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,other evidence: purified protein; gene mutation,,,NN,35457076,PubMed,10.3390/ijms23084258,Int J Mol Sci. 2022 Apr 12;23(8):4258,stieglitz.florian@mh-hannover.de,RAS-mediated effect revealed that APOC3 expression was induced by TcdB and TcdBNXN and that RAS inhibition prohibited the expression of APOC3 upon TcdB and TcdBNXN treatment,F Stieglitz 2022,2022,1 gene,Stieglitz-2022-TcdB of Clostridioides difficil,BATCH_112B,2022-06-01,MC,,,,,,,,,,,,,
,,Record 20244,PHI:123144,UniProt,A0A2I6AXF9,GenBank,AUI38916,,,CX-3,Clpks18,,,,,,,5503,Curvularia lunata,1263492,CX-3,Curvularia leaf spot,monocots,4577,Zea mays (related: maize),cv. Zhengdan 958,,,leaf,polyketide synthase which controls the melanization of conidia and the production of methyl 5-(hydroxymethyl) furan-2-carboxylate toxin.,,,,reduced virulence,,,,yes,,reduced; defective,,increased,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35685932,PubMed,10.3389/fmicb.2022.853140,Front Microbiol. 2022 May 24;13:853140,jiechen59@sjtu.edu.cn,The deletion of Clpks18 gene reduced the production of methyl 5-(hydroxymethyl)furan-2-carboxylate toxin. The virulence of 1Clpks18 mutant was significantly reduced compared with the wild type.,Z Lu 2022,2022,1 gene,Lu-2022-The Interpretation of the Role of a Po,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20245,PHI:123144,UniProt,A0A2I6AXF9,GenBank,AUI38916,,,CX-3,Clpks18,,,,,,,5503,Curvularia lunata,1263492,CX-3,Curvularia leaf spot,monocots,4577,Zea mays (related: maize),cv. Zhengdan 958,,,leaf,polyketide synthase which controls the melanization of conidia and the production of methyl 5-(hydroxymethyl) furan-2-carboxylate toxin.,,,,unaffected pathogenicity,,,,no,,increased,,increased,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,35685932,PubMed,10.3389/fmicb.2022.853140,Front Microbiol. 2022 May 24;13:853140,jiechen59@sjtu.edu.cn,The deletion of clvelB led to the increase in aerial hyphae and melanin formation.,Z Lu 2022,2022,1 gene,Lu-2022-The Interpretation of the Role of a Po,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20246,PHI:123145,UniProt,Q88BH0,GenBank,AAO53599,,,DC3000,hopK1,,R112L,,,,,317,Pseudomonas syringae,223283,pv. tomato,bacterial speck (tomato),eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Kordaat,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,NN,35616618,PubMed,10.1111/mpp.13233,Mol Plant Pathol. 2022 May 26,sangheekim@gnu.ac.kr,R112L abolishes the HopK1-mediated hypersensitive response in Lactuca sativa cv. Kordaat.,Q M Nguyen 2022,2022,3 genes,Nguyen-2022-AvrRps4 effector family processing,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20247,PHI:123146,UniProt,Q52432,GenBank,OPE56537,,,PT23,AvrRps4,,R112L; R88L; R62L,,,,,317,Pseudomonas syringae,59510,pv. pisi,bacterial speck (tomato),eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Kordaat,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised,,,NN,35616618,PubMed,10.1111/mpp.13233,Mol Plant Pathol. 2022 May 26,sangheekim@gnu.ac.kr,"R112L mutation abolished AvrRps4N/AvrRps4F-mediated hypersensitive response and suppressed electrolyte conductivity in lettuce. R88L blocks AvrRps4Fprocessing but still triggers a hypersensitive response in lettuce. The substitution of R62 to leucine in AvrRps4 did not alter the AvrRps4 processing activity. In addition, AvrRps4 R62L induced a hypersensitive response in lettuce.",Q M Nguyen 2022,2022,3 genes,Nguyen-2022-AvrRps4 effector family processing,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20248,PHI:123147,UniProt,Q3BWS7,GenBank,CAJ22686,,,85-10,XopO,,R111L; R87L; R87L/R111L; E110Q/R111L; E110Q/R111L/E114K,,,,,339,Xanthomonas campestris,,pv. vesicatoria,bacterial leaf spot,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Kordaat,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35616618,PubMed,10.1111/mpp.13233,Mol Plant Pathol. 2022 May 26,sangheekim@gnu.ac.kr,"The R111L mutation in XopO failed to abolish hypersensitive response in lettuce. The R87L and R87L/R111L double mutation in XopO induced hypersensitive response in lettuce. The double mutant XopO E110Q/R111L failed to suppress the hypersensitive response in lettuce. The triple mutant XopO E110Q/R111L/E114K successfully abolished the hypersensitive response. The single mutant XopO E114K induced an HR in lettuce, indicating that E114 alone is insufficient for XopO recognition. The double mutant XopO R111L/E114K , but not XopO E110Q/E114K , suppressed the hypersensitive response in lettuce.",Q M Nguyen 2022,2022,3 genes,Nguyen-2022-AvrRps4 effector family processing,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20249,PHI:123148,UniProt,Q59KI4,GenBank,AOW31205,,,SC5314,Ino80,,,,,,,5476,Candida albicans,,SN148,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,chromatin-remodeling ATPase,,,,reduced virulence,,,,yes,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35713098,PubMed,10.1111/mmi.14954,Mol Microbiol. 2022 Jul;118(1-2):92-104,wczhu@ion.ac.cn,"The survival ability of ino80 cells in immune cells was checked by co-incubating wild-type and ino80 cells with the murine macrophage cell line RAW264.7. The ino80 mutant cells were almost completely cleared by macrophages, whereas 20% of the wild- type cells were still alive.",Q Zhao 2022,2022,1 gene,Zhao-2022-Ino80 is required for H2A.Z eviction,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20250,PHI:123148,UniProt,Q59KI4,GenBank,AOW31205,,,SC5314,Ino80,,,,,,,5476,Candida albicans,,SN148,invasive candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney; liver,chromatin-remodeling ATPase,,,,reduced virulence,,,,yes,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35713098,PubMed,10.1111/mmi.14954,Mol Microbiol. 2022 Jul;118(1-2):92-104,wczhu@ion.ac.cn,Kidneys from mice infected with the wild- type strain contained more C. albicanscells than those infected with the ino80 strain. The fungal load of wild- type cells was also significantly higher than that of ino80cells in the liver,Q Zhao 2022,2022,1 gene,Zhao-2022-Ino80 is required for H2A.Z eviction,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20251,PHI:123149,UniProt,E9F302,GenBank,EFY97868,,,ARSEF 23,CFP1,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cysteine-free protein,,,,reduced virulence,,yes,yes,,,wild type,,defective,wild type,no,Congo red; calcofluor white; sorbitol; hydrogen peroxide; NaCl; menadione,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; NaCl: CHEBI:26710; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,NN,35736089,PubMed,10.3390/jof8060606,J Fungi (Basel). 2022 Jun 6;8(6):606,mgfeng@zju.edu.cn,Cuticle-bypassing infection by intrahemocoel injection of ~250 conidia per larva resulted in a greater reduction in virulence in the mutant of cfp1 (82%) versus the parental wild-type.,Y-N Mou 2022,2022,3 genes,Mou-2022-Three Small Cysteine-Free Proteins (C,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20252,PHI:123150,UniProt,E9F3F5,GenBank,EFY97692,,,ARSEF 23,CFP2,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cysteine-free protein,,,,reduced virulence,,yes,yes,,,reduced,,wild type,reduced,no,Congo red; calcofluor white; sorbitol; hydrogen peroxide; NaCl; menadione,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; NaCl: CHEBI:26710; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,NN,35736089,PubMed,10.3390/jof8060606,J Fungi (Basel). 2022 Jun 6;8(6):606,mgfeng@zju.edu.cn,Cuticle-bypassing infection by intrahemocoel injection of ~250 conidia per larva resulted in a greater reduction in virulence in the mutant of cfp2 (21%) versus the parental wild-type.,Y-N Mou 2022,2022,3 genes,Mou-2022-Three Small Cysteine-Free Proteins (C,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20253,PHI:123151,UniProt,A0A0B2X7N4,GenBank,KHO10933,,,ARSEF 23,CFP3,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cysteine-free protein,,,,reduced virulence,,yes,yes,,,wild type,,defective,wild type,no,Congo red; calcofluor white; sorbitol; hydrogen peroxide; NaCl; menadione,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; D-sorbitol: CHEBI:17924; H2O2: CHEBI:16240; NaCl: CHEBI:26710; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,NN,35736089,PubMed,10.3390/jof8060606,J Fungi (Basel). 2022 Jun 6;8(6):606,mgfeng@zju.edu.cn,Cuticle-bypassing infection by intrahemocoel injection of ~250 conidia per larva resulted in a greater reduction in virulence in the mutant of cfp3 (25%) versus the parental wild-type.,Y-N Mou 2022,2022,3 genes,Mou-2022-Three Small Cysteine-Free Proteins (C,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20254,PHI:123152,,no data found,GenBank,XP_042996622,,,UV-8b,UvKmt2,,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,histone methyltransferase,,,,reduced virulence,,,,,,reduced,,defective,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35736036,PubMed,10.3390/jof8060553,J Fungi (Basel). 2022 May 24;8(6):553,taozeng@zju.edu.cn,Meng-2022-UvKmt2-Mediated H3K4 Trimethylation,S Meng 2022,2022,1 gene,Meng-2022-UvKmt2-Mediated H3K4 Trimethylation,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20255,PHI:123153,UniProt,A0A0H3KAB5,GenBank,BAF68602,,,Newman,NWMN2330,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,virulence factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,35677526,PubMed,10.2147/IDR.S365314,Infect Drug Resist. 2022 Jun 2;15:2853-2864,wzjxyfy@163.com,The abscess area of mice infected with the mutant strain ΔNWMN2330 was significantly reduced compared to the wild strain.,L Liu 2022,2022,1 gene,Liu-2022-NWMN2330 May Be Associated with the V,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20256,PHI:123153,UniProt,A0A0H3KAB5,GenBank,BAF68602,,,Newman,NWMN2330,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,moths,7091,Bombyx mori (related: domestic silkworm),,,,skin,virulence factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,35677526,PubMed,10.2147/IDR.S365314,Infect Drug Resist. 2022 Jun 2;15:2853-2864,wzjxyfy@163.com,The survival time of silkworms infected with Newman was significantly shorter than the time of injection of Newman-ΔNWMN2330.,L Liu 2022,2022,1 gene,Liu-2022-NWMN2330 May Be Associated with the V,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20257,PHI:123154,UniProt,A6VF14,GenBank,ABR81513,,,PA7,dksA1,,,,,,PHI:123155,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,RNA polymerase-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35729352,PubMed,10.1038/s41598-022-14635-7,Sci Rep. 2022 Jun 21;12(1):10404,livia.leoni@uniroma3.it,The P. aeruginosa dksA1/dksA2 mutant showed impaired H2O2 tolerance in planktonic and bioflm-growing cultures and increased susceptibility to macrophages-mediated killing compared to the wild type.,A Fortuna 2022,2022,2 genes,Fortuna-2022-The Pseudomonas aeruginosa DksA1,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20258,PHI:123155,UniProt,A6VCH8,GenBank,ABR86497,,,PA7,dksA2,,,,,,PHI:123154,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,RNA polymerase-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35729352,PubMed,10.1038/s41598-022-14635-7,Sci Rep. 2022 Jun 21;12(1):10404,livia.leoni@uniroma3.it,The P. aeruginosa dksA1/dksA2 mutant showed impaired H2O2 tolerance in planktonic and bioflm-growing cultures and increased susceptibility to macrophages-mediated killing compared to the wild type.,A Fortuna 2022,2022,2 genes,Fortuna-2022-The Pseudomonas aeruginosa DksA1,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20259,PHI:123156,,no data found,,,,,,CarR,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,transcription regulator,,,carnitine degradation pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35652489,PubMed,10.1111/1462-2920.16075,Environ Microbiol. 2022 Jun 2,averhoff@bio.uni-frankfurt.de,"The ΔcarR mutant exhibited a significantly lower virulence in the presence of carnitine in comparison to the wild type cells, such as the survival of G. mellonella after infection with ΔcarRmutant in the presence of carnitine was comparable to the survival in the absence of carnitine.",J Breisch 2022,2022,1 gene,Breisch-2022-The carnitine degradation pathway,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20260,PHI:123157,UniProt,A4D9K2,GenBank,EBA27410,,,Af293,KdmA (Afu1g12332),chromosome 1,,,,,,746128,Aspergillus fumigatus,330879,Af293,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CrlOri:CD-1(ICR),,,lung,APSES transcription factor,,,,reduced virulence,,,,,,,reduced,defective,reduced,no,6-azauracil; H2O2,6-azauracil: CHEBI:53745; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35736073,PubMed,10.3390/jof8060590,J Fungi (Basel). 2022 May 31;8(6):590,mwlee12@sch.ac.kr,ΔkdmA mutant produced more gliotoxin. Mice infected with the ΔkdmA mutant showed similar lethality to mice infected with the WT strain.,Y H Choi 2022,2022,2 genes,Choi-2022-The Lysine Demethylases KdmA and Kdm,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20261,PHI:123158,UniProt,Q4WEL5,GenBank,EAL85962,,,Af293,KdmB (Afu5g03430),chromosome 5,,,,,,746128,Aspergillus fumigatus,330879,Af293,aspergillosis,rodents,10090,Mus musculus (related: house mouse),CrlOri:CD-1(ICR),,,lung,APSES transcription factor,,,,reduced virulence,,,,,,,increased,wild type,reduced,no,6-azauracil; H2O2,6-azauracil: CHEBI:53745; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35736073,PubMed,10.3390/jof8060590,J Fungi (Basel). 2022 May 31;8(6):590,mwlee12@sch.ac.kr,"The virulence of the ΔkdmB mutant was greatly decreased in mice infected with the mutant compared to the wild type. In sections of the lungs infected with the ΔkdmB strain, H&E and PAS staining revealed a rather small number of fungal cells, which was about 4-fold lower than that in mice infected with the WT strain.",Y H Choi 2022,2022,2 genes,Choi-2022-The Lysine Demethylases KdmA and Kdm,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20262,PHI:123159,UniProt,A7EPW1,GenBank,EDO04877,,,1980,SsFKH1 (SS1G_07360),,,,SsMkk1 (SS1G_00059),UniProt: A7E437; GenBank: EDN90659,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,forkhead containing transcription factor,,,MAPK pathway,reduced virulence,,,,,few and isolated lesions,reduced,,,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35547112,PubMed,10.3389/fmicb.2022.816091,Front Microbiol. 2022 Apr 25;13:816091,panhongyu@jlu.edu.cn,Knockout of SsFkh1 led to impaired sclerotia development. ΔSsfkh1 mutant showed reduced virulence on cowpea leaves.,J Cong 2022,2022,5 genes,Cong-2022-The Coupling Between Cell Wall Integ,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20263,PHI:123159,UniProt,A7EPW1,GenBank,EDO04877,,,1980,SsFKH1 (SS1G_07360),,,,SsMkk1 (SS1G_00059),UniProt: A7E437; GenBank: EDN90659,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,3917,Vigna unguiculata (related: Cowpea),,,,leaf,forkhead containing transcription factor,,,MAPK pathway,reduced virulence,,,,,few and isolated lesions,reduced,,,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35547112,PubMed,10.3389/fmicb.2022.816091,Front Microbiol. 2022 Apr 25;13:816091,panhongyu@jlu.edu.cn,Knockout of SsFkh1 led to impaired sclerotia development. ΔSsfkh1 mutant showed reduced virulence on tomato leaves.,J Cong 2022,2022,5 genes,Cong-2022-The Coupling Between Cell Wall Integ,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20264,PHI:123160,UniProt,A7E437,GenBank,EDN90659,,,1980,SsMkk1 (SS1G_00059),,,,SsFKH1 (SS1G_07360),UniProt: A7EPW1; GenBank: EDO04877,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,protein kinase domain-containing protein,,,MAPK pathway,reduced virulence,,,,yes,,reduced,,reduced,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35547112,PubMed,10.3389/fmicb.2022.816091,Front Microbiol. 2022 Apr 25;13:816091,panhongyu@jlu.edu.cn,ΔSsmkk1 mutant completely lost the sclerotium-producing ability and showed reduced virulence. ΔSsmkk mutant showed a reduced growth rate on PDA and twisted hyphae morphology.,J Cong 2022,2022,5 genes,Cong-2022-The Coupling Between Cell Wall Integ,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20265,PHI:123161,UniProt,A7F066,GenBank,EDN95108,,,1980,SsBck1 (SS1G_10983),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,protein kinase domain-containing protein,,,MAPK pathway,reduced virulence,,,,,,reduced,,,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35547112,PubMed,10.3389/fmicb.2022.816091,Front Microbiol. 2022 Apr 25;13:816091,panhongyu@jlu.edu.cn,ΔSsBck1 mutant produced less number of sclerotia and showed reduced virulence.,J Cong 2022,2022,5 genes,Cong-2022-The Coupling Between Cell Wall Integ,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20266,PHI:123162,UniProt,A7EJF2,GenBank,EDO02968,,,1980,SsSmk3 (SS1G_05445),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,mitogen-activated protein kinase,,,MAPK pathway,reduced virulence,,,,yes,,reduced,,reduced,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35547112,PubMed,10.3389/fmicb.2022.816091,Front Microbiol. 2022 Apr 25;13:816091,panhongyu@jlu.edu.cn,ΔSsmkk3 mutant produced less number of sclerotia and showed reduced virulence. ΔSsmkk3 mutant showed a reduced growth rate on PDA and twisted hyphae morphology.,J Cong 2022,2022,5 genes,Cong-2022-The Coupling Between Cell Wall Integ,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20267,PHI:123163,UniProt,A7F8U5,GenBank,EDN99166,,,1980,SsPkc1 (SS1G_14026),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980 UF-70,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,protein kinase C,,,MAPK pathway,reduced virulence,,,,,,reduced,,,,no,Congo red; calcofluor white; H2O2,Congo red: CHEBI:34653; calcoflour white: CHEBI:50011; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35547112,PubMed,10.3389/fmicb.2022.816091,Front Microbiol. 2022 Apr 25;13:816091,panhongyu@jlu.edu.cn,ΔSsPck1 mutant produced less number of sclerotia and showed reduced virulence.,J Cong 2022,2022,5 genes,Cong-2022-The Coupling Between Cell Wall Integ,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20268,PHI:123164,UniProt,A7ERZ9,GenBank,EDN92241,,,1980,SsCut1 (SS1G_08104),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,cutinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35628781,PubMed,10.3390/jof8050526,J Fungi (Basel). 2022 May 20;8(5):526,jiasencheng@mail.hzau.edu.cn,"ΔSsCut1 mutants showed reduced cutinase activity and virulence, but the deletion of the SsCut1 gene had no effect on the growth rate, colony morphology, oxalic acid production, infection cushion formation and sclerotial development.",Y Gong 2022,2022,1 gene,Gong-2022-Sclerotinia sclerotiorum&amp;nbsp;Ss,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20269,PHI:123165,UniProt,A7ERZ9,GenBank,EDN92241,,,1980,SsCut1 (SS1G_08104),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),,,,leaf,cutinase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35628781,PubMed,10.3390/jof8050526,J Fungi (Basel). 2022 May 20;8(5):526,jiasencheng@mail.hzau.edu.cn,"ΔSsCut1 mutants showed reduced cutinase activity and virulence, but the deletion of the SsCut1 gene had no effect on the growth rate, colony morphology, oxalic acid production, infection cushion formation and sclerotial development.",Y Gong 2022,2022,1 gene,Gong-2022-Sclerotinia sclerotiorum&amp;nbsp;Ss,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20270,PHI:123166,UniProt,A0A5W0R9X0,GenBank,QPQ67540,,,R18.1078,phoU,,R184G,,PhoU interacts with PhoR,UniProt: Q8ZRE1; GenBank: AAL19352,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,phosphate-specific transport system accessory protein PhoU,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised; gene deletion: full,,,NN,35638741,PubMed,10.1128/mbio.00811-22,mBio. 2022 Jun 28;13(3):e0081122,eunjinlee@korea.ac.kr,"The phoU variant with the Arg184-to-Gly substitution decreased replication within macrophages, reaching only 20% of that of the wild type. Deletion of phoU also caused reduced virulence.",S Choi 2022,2022,2 genes,Choi-2022-A Dual Regulatory Role of the PhoU P,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20271,PHI:123166,UniProt,A0A5W0R9X0,GenBank,QPQ67540,,,R18.1078,phoU,,R184G,,PhoU interacts with PhoR,UniProt: Q8ZRE1; GenBank: AAL19352,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,phosphate-specific transport system accessory protein PhoU,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,NN,35638741,PubMed,10.1128/mbio.00811-22,mBio. 2022 Jun 28;13(3):e0081122,eunjinlee@korea.ac.kr,Arg184-to-Gly substitution in PhoU decreases mouse virulence.,S Choi 2022,2022,2 genes,Choi-2022-A Dual Regulatory Role of the PhoU P,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20272,PHI:123166,UniProt,A0A5W0R9X0,GenBank,QPQ67540,,,R18.1078,phoU,,,,PhoU interacts with PhoR,UniProt: Q8ZRE1; GenBank: AAL19352,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,phosphate-specific transport system accessory protein PhoU,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35638741,PubMed,10.1128/mbio.00811-22,mBio. 2022 Jun 28;13(3):e0081122,eunjinlee@korea.ac.kr,Deletion of phoU also caused loss of pathogenicity determined by meauring survival of mice.,S Choi 2022,2022,2 genes,Choi-2022-A Dual Regulatory Role of the PhoU P,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20273,PHI:123167,UniProt,D0ZLQ7,GenBank,AAD16960,,,14028s,MgtC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,phosphate-specific transport system accessory protein PhoU,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35638741,PubMed,10.1128/mbio.00811-22,mBio. 2022 Jun 28;13(3):e0081122,eunjinlee@korea.ac.kr,The mgtC deletion variant decreased replication within macrophages.,S Choi 2022,2022,2 genes,Choi-2022-A Dual Regulatory Role of the PhoU P,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20274,PHI:123167,UniProt,D0ZLQ7,GenBank,AAD16960,,,14028s,MgtC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,phosphate-specific transport system accessory protein PhoU,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35638741,PubMed,10.1128/mbio.00811-22,mBio. 2022 Jun 28;13(3):e0081122,eunjinlee@korea.ac.kr,Deletion of mgtC also caused loss of pathogenicity determined by meauring survival of mice.,S Choi 2022,2022,2 genes,Choi-2022-A Dual Regulatory Role of the PhoU P,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20275,PHI:123168,UniProt,A0A8E6NAW3,GenBank,QPQ68955,,,R18.1078,pta,,Δpat Δpta,,,,PHI:123169,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,phosphate acetyltransferase,,,protein acetylation pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35622226,PubMed,10.1007/s12275-022-2095-y,J Microbiol. 2022 May 27,jungshinlee@kangwon.ac.kr,The Δpat Δpta mutant markedly decreased replication inside macrophages by about 7 fold compared to that of wild-type.,J Koo 2022,2022,2 genes,Koo-2022-Pat- and Pta-mediated protein acetyla,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20276,PHI:123169,UniProt,A0A0D6F9C4,GenBank,CAD5309993,,,R18.1078,pat,,Δpat Δpta,,,,PHI:123168,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774A1 cell line,,,macrophage,phosphate acetyltransferase,,,protein acetylation pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35622226,PubMed,10.1007/s12275-022-2095-y,J Microbiol. 2022 May 27,jungshinlee@kangwon.ac.kr,The Δpat Δpta mutant markedly decreased replication inside macrophages by about 7 fold compared to that of wild-type.,J Koo 2022,2022,2 genes,Koo-2022-Pat- and Pta-mediated protein acetyla,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20277,PHI:123168,UniProt,A0A8E6NAW3,GenBank,QPQ68955,,,R18.1078,pta,,Δpat Δpta,,,,PHI:123169,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,macrophage,phosphate acetyltransferase,,,protein acetylation pathway,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35622226,PubMed,10.1007/s12275-022-2095-y,J Microbiol. 2022 May 27,jungshinlee@kangwon.ac.kr,"When Δpat Δpta mutant Salmonella strains were injected into mice intraperitoneally, the Δpat Δpta mutant Salmonella was completely attenuated for mouse virulence compared to wild-type.",J Koo 2022,2022,2 genes,Koo-2022-Pat- and Pta-mediated protein acetyla,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20278,PHI:123169,UniProt,A0A0D6F9C4,GenBank,CAD5309993,,,R18.1078,pat,,Δpat Δpta,,,,PHI:123168,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,macrophage,phosphate acetyltransferase,,,protein acetylation pathway,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35622226,PubMed,10.1007/s12275-022-2095-y,J Microbiol. 2022 May 27,jungshinlee@kangwon.ac.kr,"When Δpat Δpta mutant Salmonella strains were injected into mice intraperitoneally, the Δpat Δpta mutant Salmonella was completely attenuated for mouse virulence compared to wild-type.",J Koo 2022,2022,2 genes,Koo-2022-Pat- and Pta-mediated protein acetyla,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20279,PHI:123170,,no data found,GenBank,JH993691,,,PHI26,PMA1,chromosome unknown,,,,,,36651,Penicillium digitatum,,Saccardo (DSM 62840),green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Newhall,,,fruit,plasma membrane H+ ATPase,,,,reduced virulence,,,,yes,reduced lesion diameter,,,reduced,reduced,no,bifonazole: omeprazole; lansoprazole,bifonazole: CHEBI:31286; omeprazole: CHEBI:7772; lansoprazole: CHEBI:6375,,,,,altered gene expression / gene regulation: silencing,,,NN,35771244,PubMed,10.1007/s00253-022-12036-4,Appl Microbiol Biotechnol . 2022 Jun 30,yszhen@mail.hzau.edu.cn,"The PMA1 gene silencing signifcantly decreased the four plant cell wall-degrading enzyme activities. Silencing the PMA1 gene reduces cell growth and pathogenicity, and increases susceptibility of P. digitatum to proton pump inhibitors.",J Li 2022,2022,1 gene,Li-2022-The plasma membrane H(+)-ATPase is cri,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20280,PHI:123170,,no data found,GenBank,JH993691,,,PHI26,PMA1,chromosome unknown,,,,,,36651,Penicillium digitatum,,Saccardo (DSM 62840),green mold,eudicots,2711,Citrus sinensis (related: sweet orange),cv. Newhall,,,fruit,plasma membrane H+ ATPase,,,,increased virulence (hypervirulence),,,,no,increased lesion diameter,,,increased,increased,no,bifonazole: omeprazole; lansoprazole,bifonazole: CHEBI:31286; omeprazole: CHEBI:7772; lansoprazole: CHEBI:6375,,,,,altered gene expression / gene regulation: overexpression,,,NN,35771244,PubMed,10.1007/s00253-022-12036-4,Appl Microbiol Biotechnol . 2022 Jun 30,yszhen@mail.hzau.edu.cn,"PMA1 overexpression promoted growth of P. digitatum. Overexpressing the PMA1 gene rincreased pathogenicity, and reduced susceptibility of P. digitatum to proton pump inhibitors.",J Li 2022,2022,1 gene,Li-2022-The plasma membrane H(+)-ATPase is cri,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20281,PHI:123171,UniProt,A0A828ABX9,GenBank,EFK3427938,,,192878,Map,,,,,,,562,Escherichia coli,,serotype O111:K58,mastitis,rodents,10090,Mus musculus (related: house mouse),CrlOri:CD-1(ICR),,,breast,T3SS effector protein map,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35563295,PubMed,10.3390/ijms23094907,Int J Mol Sci. 2022 Apr 28;23(9):4907,jiufeng_wang@hotmail.com,"After the map gene was knocked out, breast inflammation and apoptosis in mice were significantly alleviated.",Y Li 2022,2022,1 gene,Li-2022-Map of Enteropathogenic Escherichia co,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20282,PHI:123172,,no data found,,,,,,InvL,,,,,,,470,Acinetobacter baumannii,,UPAB1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bladder,invasin-like adhesin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35638734,PubMed,10.1128/mbio.00258-22,mBio. 2022 Jun 28;13(3):e0025822,mariofeldman@wustl.edu,"The ΔinvL mutant had a significant reduction in catheter binding, exhibiting approximately a 100-fold decrease relative to the WT strain, and this phenotype was partially reversed by genetic complementation. ΔinvL also had a significant defect in bladder colonization relative to the WT strain",C D Jackson-Litteken 2022,2022,2 genes,"Jackson-Litteke-2022-InvL, an Invasin-Like Adh",BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20283,PHI:123173,UniProt,A0A062KYV9,GenBank,KCY48701,,,1571545,gspD,,,,,,,470,Acinetobacter baumannii,,UPAB1,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bladder,type II secretion (T2S) system that is responsible for secretion of InvL,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35638734,PubMed,10.1128/mbio.00258-22,mBio. 2022 Jun 28;13(3):e0025822,mariofeldman@wustl.edu,The ΔgspD mutant exhibited decreased binding to the catheter and colonization of the mouse bladder.,C D Jackson-Litteken 2022,2022,2 genes,"Jackson-Litteke-2022-InvL, an Invasin-Like Adh",BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20284,PHI:123174,,no data found,GenBank,AAT04645,,,4b F2365,LMOf2365_1875,,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colorectal adenocarcinoma cell line,"manganese ABC transporter, ATP-binding protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35617277,PubMed,10.1371/journal.pone.0268924,PLoS One. 2022 May 26;17(5):e0268924,yanhong.liu@usda.gov,ΔLMOf2365_1875 formed 71% lower number of plaques compared to the wild type.,Y Liu 2022,2022,2 genes,Liu-2022-Involvement of a putative ATP-Binding,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20285,PHI:123175,,no data found,GenBank,AAT04647,,,4b F2365,LMOf2365_1877,,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colorectal adenocarcinoma cell line,"manganese ABC transporter, ATP-binding protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35617277,PubMed,10.1371/journal.pone.0268924,PLoS One. 2022 May 26;17(5):e0268924,yanhong.liu@usda.gov,ΔLMOf2365_1877 formed lower number of plaques compared to the wild type.,Y Liu 2022,2022,2 genes,Liu-2022-Involvement of a putative ATP-Binding,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20286,PHI:123174,,no data found,GenBank,AAT04645,,,4b F2365,LMOf2365_1875,,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"manganese ABC transporter, ATP-binding protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35617277,PubMed,10.1371/journal.pone.0268924,PLoS One. 2022 May 26;17(5):e0268924,yanhong.liu@usda.gov,The mutant exhibited reduced mortality. Virulence of the deletion mutant ΔLMOf2365_1875 was lower than that of the LMOf2365 parental strain.,Y Liu 2022,2022,2 genes,Liu-2022-Involvement of a putative ATP-Binding,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20287,PHI:123175,,no data found,GenBank,AAT04647,,,4b F2365,LMOf2365_1877,,,,,,,1639,Listeria monocytogenes,265669,F2365,listeriosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"manganese ABC transporter, ATP-binding protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35617277,PubMed,10.1371/journal.pone.0268924,PLoS One. 2022 May 26;17(5):e0268924,yanhong.liu@usda.gov,The mutant exhibited significantly reduced mortality. Virulence of the deletion mutant ΔLMOf2365_1877 was lower than that of the LMOf2365 parental strain.,Y Liu 2022,2022,2 genes,Liu-2022-Involvement of a putative ATP-Binding,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20288,PHI:123176,UniProt,J9VNE8,GenBank,AFR95982,,,H99,mar1,chromosome 7,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,macrophage activating regulator of cell wall,,,,reduced virulence,,,,,,,,reduced,,no,CoCl2,CoCl2: CHEBI:35696,,,,,gene deletion: full; gene complementation,,,NN,35587201,PubMed,10.1128/iai.00580-21,Infect Immun . 2022 Jun 16;90(6):e0058021,andrew.alspaugh@duke.edu,"The mar1 deletion mutant strain persists long term in a murine inhalation model of cryptococcosis, inducing a chronic pulmonary granulomatous response. Murine infections with the mar1Δ mutant strain are characterized by reduced fungal burden and an altered host immune response, likely due to inability of the mar1Δ mutant strain to properly employ virulence factors.",C L Telzrow 2022,2022,1 gene,Telzrow-2022-An Immunogenic and Slow-Growing C,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20289,PHI:123177,UniProt,J4UH12,GenBank,EJP62332,,,ARSEF 2860,BbPlin1 (NCBI EJP62332),chromosome unknown,,,,,,176275,Beauveria bassiana,1436183,Bb0062,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,perilipin MPL1-like protein,,,,reduced virulence,,,,yes,,increased,,wild type,wild type,no,H2O2; NaCl; menadione; Congo red,H2O2: CHEBI:16240; NaCl: CHEBI:26710; menadione: CHEBI:28869; Congo red: CHEBI:34653,,,,,gene disruption; gene complementation,,,NN,35736117,PubMed,10.3390/jof8060634,J Fungi (Basel). 2022 Jun 15;8(6):634,fyh@swu.edu.cn,"Characterization of a targeted gene deletion strain (Δ BbPlin1) revealed a dramatic (>30%) reduction in cellular LD content, promotion of aerial hyphal growth, and a small decrease in virulence, with little to no effects on vegetative growth and stress responses.",X Wang 2022,2022,1 gene,Wang-2022-A Perilipin Affects Lipid Droplet Ho,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20290,PHI:123178,UniProt,X0KZF9,GenBank,EXM02100,,,54006,FoSSP1 (FOIG_06406),chromosome unknown,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4,vascular wilt,monocots,4641,Musa acuminata (related: dwarf banana),AAA group cv. Brazilian,,,leaf; pseudostem; root,small secreted protein,,,,increased virulence (hypervirulence),,,,,,increased,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35620677,PubMed,10.3389/fpls.2022.873451,Front Plant Sci. 2022 May 10;13:873451,chen.daipeng@163.com,The deletion mutant Fossp1 was normal in growth rate but increased in conidiation and virulence.,Y Wang 2022,2022,1 gene,Wang-2022-The Small Secreted Protein FoSsp1 El,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20291,PHI:123179,UniProt,Q883C0,GenBank,AAO55957,,,DC3000,PscC (PSPTO_2448),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,methyl-accepting chemotaxis protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35689388,PubMed,10.1111/mpp.13238,Mol Plant Pathol. 2022 Jun 10,emilia.lopez@upm.es,Mutation of the PsPto-PscC chemoreceptor caused a reduced chemotactic response towards GABA and L-proline which in turn impaired entry and reduced virulence in tomato plants.,S Santamaría-Hernando 2022,2022,1 gene,Santamaría-Hern-2022-Pseudomonas syringae pv,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20292,PHI:123179,UniProt,Q883C0,GenBank,AAO55957,,,DC3000,PscC (PSPTO_2448),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0; gad1/2,,,leaf,methyl-accepting chemotaxis protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35689388,PubMed,10.1111/mpp.13238,Mol Plant Pathol. 2022 Jun 10,emilia.lopez@upm.es,No differences were observed either in entry or in virulence between the WT and the mutant strain in A. thaliana plants.,S Santamaría-Hernando 2022,2022,1 gene,Santamaría-Hern-2022-Pseudomonas syringae pv,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20293,PHI:123180,UniProt,A0A8E5MEA6,GenBank,QUC17088,,,UV-8b,UvVEA (UV8b_01329),chromosome 1,,,UvVELB (UV8b_04876),UniProt: A0A8E5HS55; GenBank: QUC20635,,1159556,Ustilaginoidea virens,,Jt209,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Liangyoupeijiu 9,,,spikelet,velvet domain-containing protein,,,,unaffected pathogenicity,,,,,,increased,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35628735,PubMed,10.3390/jof8050479,J Fungi (Basel). 2022 May 4;8(5):479,liuyf@jaas.ac.cn,Deletion of UvVEA affected the conidiation of U. virens but had no effect on the virulence of this pathogen.,M Yu 2022,2022,2 genes,Yu-2022-The Velvet Protein UvVEA Regulates Con,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20294,PHI:123181,UniProt,A0A8E5HS55,GenBank,QUC20635,,,UV-8b,UvVELB (UV8b_04876),chromosome 4,,,UvVEA (UV8b_01329),UniProt: A0A8E5MEA6; GenBank: QUC17088,,1159556,Ustilaginoidea virens,,Jt209,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Liangyoupeijiu 9,,,spikelet,velvet domain-containing protein,,,,unaffected pathogenicity,,,,,,increased,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35628735,PubMed,10.3390/jof8050479,J Fungi (Basel). 2022 May 4;8(5):479,liuyf@jaas.ac.cn,Deletion of UvVELB affected the conidiation of U. virens but had no effect on the virulence of this pathogen.,M Yu 2022,2022,2 genes,Yu-2022-The Velvet Protein UvVEA Regulates Con,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20295,PHI:123182,UniProt,E1AYJ2,GenBank,ADM80412,,,CFBP1851,TAL20,,,,,,,53413,Xanthomonas axonopodis,,pv. manihotis,bacterial blight,eudicots,3983,Manihot esculenta (related: cassava),cv. TME419,,,leaf,TAL effector protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35729628,PubMed,10.1186/s13007-022-00906-x,Plant Methods. 2022 Jun 21;18(1):86,athinova6@hotmail.com,"Water-soaking appeared reduced in Xam668ΔTAL20 infection sites as compared to wildtype Xam668sites. Additionally, Xam668ΔTAL20 infection sites appeared lighter in color compared to the darker lesions that develop at wildtype Xam668sites.",K Elliott 2022,2022,1 gene,Elliott-2022-A comparison of ImageJ and machin,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20296,PHI:123183,UniProt,A0A125YLS5,GenBank,EPR63398,,,GT1,TgANT (TGGT1_249900),,,,,,,5811,Toxoplasma gondii,383379,RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,ADP/ATP translocase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35642006,PubMed,10.1186/s13071-022-05295-7,Parasit Vectors. 2022 May 31;15(1):185,qunliu@cau.edu.cn,"The survival curve showed that all mice infected with 100 RHΔku80 tachyzoites died within 7 days, while mice receiving 100 Δant tachyzoites survived for 21 days.",Y Wu 2022,2022,1 gene,Wu-2022-Depletion of Toxoplasma adenine nucleo,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20297,PHI:123184,UniProt,Q01563,GenBank,ADM99379,,,3937,outB,,,,,UniProt: Q01565; GenBank: ADM99376,,204038,Dickeya dadantii,,A5954,soft rot,eudicots,13427,Cichorium intybus (related: chicory),,,,leaf,general secretion pathway protein B,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35546537,PubMed,10.1128/mbio.00253-22,mBio. 2022 Jun 28;13(3):e0025322,vladimir.shevchik@insa-lyon.fr,Pathogenicity assays with chicory leaves clearly showed that the D. dadantii ΔoutB mutant was barely virulent in comparison with the wild-type strain. OutB was shown to interact with outD.,S Zhang 2022,2022,1 gene,Zhang-2022-Scaffolding Protein GspB_OutB Facil,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20298,PHI:123185,UniProt,Q6FTW5,GenBank,CAG59253,,,CBS 138,GCN5,chromosome F,,,,,,5478,Candida glabrata,284593,ATCC 2001,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,histone acetyltransferase,,,,reduced virulence,,,,,,,,reduced,,no,posaconazole; voriconazole; itraconazole; fluconazole; caspofungin; anidulafungin; micafungin; manogepix; ibrexafungerp,posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; fluconazole: CHEBI:46081; caspofungin: CHEBI:474180; anidulafungin: CHEBI:55346; micafungin: CHEBI:600520; manogepix CAS: CAS:36339-60-5; ibrexafungerp CAS: CAS:1207753-03-4,,,,,gene deletion: full; gene complementation,,,NN,35658596,PubMed,10.1128/spectrum.00963-22,Microbiol Spectr. 2022 Jun 29;10(3):e0096322,yanan.zhao@hmh-cdi.org,Significantly reduced intracellular replication at 24 h post infection was observed with gcn5Δ cells compared to cells with Gcn5 function.,S Yu 2022,2022,1 gene,Yu-2022-Histone Acetylation Regulator Gcn5 Med,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20299,PHI:123186,UniProt,C5AF80,GenBank,ACR28487,,,BGR1,GluR (BGLU_1G13360),,gluR::Tn3-gusA133,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Milyang 23,,,stem,osmolarity response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35717678,PubMed,10.1111/mpp.13241,Mol Plant Pathol. 2022 Jun 19,sourire11@snu.ac.kr,The gluR mutant showed significantly reduced disease symptoms in rice plant with an index of 0.34 ± 0.15 compared to wild- type BGR1 with a disease index of 1.0 ± 0.52.,J Marunga 20222022,2020,2 genes,Marunga-2022-Hierarchical regulation of Burkho,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20300,PHI:123186,UniProt,C5AF80,GenBank,ACR28487,,,BGR1,GluR (BGLU_1G13360),,gluR::Tn3-gusA133,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,osmolarity response regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35717678,PubMed,10.1111/mpp.13241,Mol Plant Pathol. 2022 Jun 19,sourire11@snu.ac.kr,The gluR mutant failed to induce hypersensitive response in tobacco plant.,J Marunga 20222022,2020,2 genes,Marunga-2022-Hierarchical regulation of Burkho,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20301,PHI:123187,UniProt,C5AF95,GenBank,ACR28502,,,BGR1,Lon,chromosome 1,lon::Gm,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),cv. Milyang 23,,,stem,Lon protease,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35717678,PubMed,10.1111/mpp.13241,Mol Plant Pathol. 2022 Jun 19,sourire11@snu.ac.kr,The Lon mutant exhibited no disease symptoms in rice stems.,J Marunga 20222022,2020,2 genes,Marunga-2022-Hierarchical regulation of Burkho,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20302,PHI:123187,UniProt,C5AF95,GenBank,ACR28502,,,BGR1,Lon,chromosome 1,lon::Gm,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,Lon protease,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35717678,PubMed,10.1111/mpp.13241,Mol Plant Pathol. 2022 Jun 19,sourire11@snu.ac.kr,The Lon mutant failed to induce hypersensitive response in tobacco plant.,J Marunga 20222022,2020,2 genes,Marunga-2022-Hierarchical regulation of Burkho,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20303,PHI:123186,UniProt,C5AF80,GenBank,ACR28487,,,BGR1,GluR (BGLU_1G13360),,gluR::Tn3-gusA133/lon::Gm,,,,PHI:123187,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,osmolarity response regulator,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35717678,PubMed,10.1111/mpp.13241,Mol Plant Pathol. 2022 Jun 19,sourire11@snu.ac.kr,The gluR mutant failed to induce hypersensitive response in tobacco plant.,J Marunga 20222022,2020,2 genes,Marunga-2022-Hierarchical regulation of Burkho,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20304,PHI:123187,UniProt,C5AF95,GenBank,ACR28502,,,BGR1,Lon,chromosome 1,gluR::Tn3-gusA133/lon::Gm,,,,PHI:123186,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,Lon protease,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35717678,PubMed,10.1111/mpp.13241,Mol Plant Pathol. 2022 Jun 19,sourire11@snu.ac.kr,The GluR/Lon double mutant failed to induce hypersensitive response in tobacco plant.,J Marunga 20222022,2020,2 genes,Marunga-2022-Hierarchical regulation of Burkho,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20305,PHI:123188,UniProt,Q2G0Z2,GenBank,ABD29535,,,NCTC 8325,SaoC,,,,,,,1280,Staphylococcus aureus,561307,RN4220,soft tissue lesion; pneumonia; toxic shock syndrome,primates,9606,Homo sapiens (related: human),,,,dermal fibroblast,uncharacterized protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35742885,PubMed,10.3390/ijms23126443,Int J Mol Sci. 2022 Jun 9;23(12):6443,m.bukowski@uj.edu.pl,Deletion of SaoC resulted in decreased survival of the bacteria in human dermal fibroblasts.,M Bukowski 2022,2022,2 genes,Bukowski-2022-Staphylococcal saoABC Operon Cod,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20306,PHI:123189,,no data found,,,,,,SaoA,,,,,,,1280,Staphylococcus aureus,561307,RN4220,soft tissue lesion; pneumonia; toxic shock syndrome,primates,9606,Homo sapiens (related: human),,,,dermal fibroblast,uncharacterized protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35742885,PubMed,10.3390/ijms23126443,Int J Mol Sci. 2022 Jun 9;23(12):6443,m.bukowski@uj.edu.pl,There was no difference in survival in human dermal fibroblasts between wild-type and SaoA mutants.,M Bukowski 2022,2022,2 genes,Bukowski-2022-Staphylococcal saoABC Operon Cod,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20307,PHI:123190,UniProt,O06218,GenBank,CCP44935,,,H37Rv,Rv2159c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,peroxidase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; CuSO4; ZnSO4; SDS,H2O2: CHEBI:16240; CuSO4: CHEBI:23414; ZnSO4: CHEBI:35176; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,35745538,PubMed,10.3390/pathogens11060684,Pathogens. 2022 Jun 14;11(6):684,bhargavi.gunapati@gmail.com,Deletion of Rv2159c induced the expression of proinflammatory cytokines. Rv2159c is involved in maintaining redox homeostasis and virulence of M.tuberculosis.,G Bhargavi 2022,2022,1 gene,Bhargavi-2022-Role of a Putative Alkylhydroper,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20308,PHI:123190,UniProt,O06218,GenBank,CCP44935,,,H37Rv,Rv2159c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10141,Cavia porcellus (related: Domestic Guinea pig),Duncan-Hartley,,,lung; spleen,peroxidase,,,,reduced virulence,,,,,,,,wild type,,no,H2O2; CuSO4; ZnSO4; SDS,H2O2: CHEBI:16240; CuSO4: CHEBI:23414; ZnSO4: CHEBI:35176; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,35745538,PubMed,10.3390/pathogens11060684,Pathogens. 2022 Jun 14;11(6):684,bhargavi.gunapati@gmail.com,Deletion of Rv2159c induced the expression of proinflammatory cytokines. Rv2159c is involved in maintaining redox homeostasis and virulence of M.tuberculosis.,G Bhargavi 2022,2022,1 gene,Bhargavi-2022-Role of a Putative Alkylhydroper,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20309,PHI:123191,UniProt,J5JI18,GenBank,EJP63081,,,ARSEF 2860,hsp20 (BBA_07886),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,Hsp20-like protein,,,,reduced virulence,,,,,,wild type,,wild type,defective,no,Congo red; menadione; H2O2,Congo red: CHEBI:34653; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35743166,PubMed,10.3390/ijms23126717,Int J Mol Sci. 2022 Jun 16;23(12):6717,zgbees@gdim.cn,three sHsps containing conserved alpha-crystallin domain exist in the genome of B. bassiana and are transcriptionally interrelated under normal and heat-shocked conditions,G Zhou 2022,2022,3 genes,Zhou-2022-Differential Roles of Three α-Crysta,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20310,PHI:123192,UniProt,J4UH27,GenBank,EJP62362,,,ARSEF 2860,hsp30a (BBA_08688),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,heat shock protein 30,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,Congo red; menadione; H2O2,Congo red: CHEBI:34653; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35743166,PubMed,10.3390/ijms23126717,Int J Mol Sci. 2022 Jun 16;23(12):6717,zgbees@gdim.cn,three sHsps containing conserved alpha-crystallin domain exist in the genome of B. bassiana and are transcriptionally interrelated under normal and heat-shocked conditions,G Zhou 2022,2022,3 genes,Zhou-2022-Differential Roles of Three α-Crysta,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20311,PHI:123193,UniProt,J4UT97,GenBank,EJP69022,,,ARSEF 2860,hsp30b (BBA_02057),,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,heat shock protein 30,,,,reduced virulence,,,,,,wild type,,reduced,defective,no,Congo red; menadione; H2O2,Congo red: CHEBI:34653; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35743166,PubMed,10.3390/ijms23126717,Int J Mol Sci. 2022 Jun 16;23(12):6717,zgbees@gdim.cn,three sHsps containing conserved alpha-crystallin domain exist in the genome of B. bassiana and are transcriptionally interrelated under normal and heat-shocked conditions,G Zhou 2022,2022,3 genes,Zhou-2022-Differential Roles of Three α-Crysta,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20312,PHI:123194,UniProt,Q59X24,,,,,,ppx1 (C2_06110W_A),,,,,,PHI:123195,5476,Candida albicans,,JC2210,systemic candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,polyphosphatase,,,,reduced virulence,,,,,,,,defective,,no,NaCl; menadione; hydroxyurea; methyl methanesulfonate,NaCl: CHEBI:26710; menadione: CHEBI:28869; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255,,,,,gene deletion: full; gene complementation,,,NN,35575514,PubMed,10.1128/mbio.00342-22,mBio. 2022 Jun 28;13(3):e0034222,janet.quinn@ncl.ac.uk,"Cells lacking both polyphosphatases are exquisitely sensitive to DNA replication stress, indicating that polyP mobilization is needed to support the phosphate-demanding process of DNA replication",Y Ahmed 2022,2022,4 genes,Ahmed-2022-Blocking Polyphosphate Mobilization,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20313,PHI:123195,UniProt,A0A1D8PQR0,,,,,,ppn1 (C7_00980W_A),,,,,,PHI:123194,5476,Candida albicans,,JC2210,systemic candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,polyphosphatase,,,,reduced virulence,,,,,,,,defective,,no,NaCl; menadione; hydroxyurea; methyl methanesulfonate,NaCl: CHEBI:26710; menadione: CHEBI:28869; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255,,,,,gene deletion: full; gene complementation,,,NN,35575514,PubMed,10.1128/mbio.00342-22,mBio. 2022 Jun 28;13(3):e0034222,janet.quinn@ncl.ac.uk,"Cells lacking both polyphosphatases are exquisitely sensitive to DNA replication stress, indicating that polyP mobilization is needed to support the phosphate-demanding process of DNA replication",Y Ahmed 2022,2022,4 genes,Ahmed-2022-Blocking Polyphosphate Mobilization,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20314,PHI:123196,UniProt,A0A1D8PMD1,GenBank,AOW29300,,,SC5314,pho4,chromosome 4,,,,,,5476,Candida albicans,,JC1928,systemic candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,phosphate-sensing transcription factor,,,,reduced virulence,,,,,,,,defective,,no,NaCl; menadione; hydroxyurea; methyl methanesulfonate,NaCl: CHEBI:26710; menadione: CHEBI:28869; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255,,,,,gene deletion: full; gene complementation,,,NN,35575514,PubMed,10.1128/mbio.00342-22,mBio. 2022 Jun 28;13(3):e0034222,janet.quinn@ncl.ac.uk,"Cells lacking both polyphosphatases are exquisitely sensitive to DNA replication stress, indicating that polyP mobilization is needed to support the phosphate-demanding process of DNA replication",Y Ahmed 2022,2022,4 genes,Ahmed-2022-Blocking Polyphosphate Mobilization,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20315,PHI:123197,UniProt,Q59PH5,GenBank,AOW29095,,,SC5314,vtc4,chromosome 4,,,,,,5476,Candida albicans,,JC1984,systemic candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,vacuolar transporter chaperone,,,,reduced virulence,,,,,,,,defective,,no,NaCl; menadione; hydroxyurea; methyl methanesulfonate,NaCl: CHEBI:26710; menadione: CHEBI:28869; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255,,,,,gene deletion: full; gene complementation,,,NN,35575514,PubMed,10.1128/mbio.00342-22,mBio. 2022 Jun 28;13(3):e0034222,janet.quinn@ncl.ac.uk,"Cells lacking both polyphosphatases are exquisitely sensitive to DNA replication stress, indicating that polyP mobilization is needed to support the phosphate-demanding process of DNA replication",Y Ahmed 2022,2022,4 genes,Ahmed-2022-Blocking Polyphosphate Mobilization,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20316,PHI:123194,UniProt,Q59X24,,,,,,ppx1 (C2_06110W_A),,,,,,PHI:123195,5476,Candida albicans,,JC2210,systemic candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,polyphosphatase,,,,reduced virulence,,,,,,,,defective,,no,NaCl; menadione; hydroxyurea; methyl methanesulfonate,NaCl: CHEBI:26710; menadione: CHEBI:28869; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255,,,,,gene deletion: full; gene complementation,,,NN,35575514,PubMed,10.1128/mbio.00342-22,mBio. 2022 Jun 28;13(3):e0034222,janet.quinn@ncl.ac.uk,"Cells lacking both polyphosphatases are exquisitely sensitive to DNA replication stress, indicating that polyP mobilization is needed to support the phosphate-demanding process of DNA replication",Y Ahmed 2022,2022,4 genes,Ahmed-2022-Blocking Polyphosphate Mobilization,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20317,PHI:123195,UniProt,A0A1D8PQR0,,,,,,ppn1 (C7_00980W_A),,,,,,PHI:123194,5476,Candida albicans,,JC2210,systemic candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,polyphosphatase,,,,reduced virulence,,,,,,,,defective,,no,NaCl; menadione; hydroxyurea; methyl methanesulfonate,NaCl: CHEBI:26710; menadione: CHEBI:28869; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255,,,,,gene deletion: full; gene complementation,,,NN,35575514,PubMed,10.1128/mbio.00342-22,mBio. 2022 Jun 28;13(3):e0034222,janet.quinn@ncl.ac.uk,"Cells lacking both polyphosphatases are exquisitely sensitive to DNA replication stress, indicating that polyP mobilization is needed to support the phosphate-demanding process of DNA replication",Y Ahmed 2022,2022,4 genes,Ahmed-2022-Blocking Polyphosphate Mobilization,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20318,PHI:123198,UniProt,P0AGB6,GenBank,AAC45314,,,K12 W3110,rpoE,,,,,,,562,Escherichia coli,439184,RS218,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,extracytoplasmic function sigma factor,,,,reduced virulence,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35630325,PubMed,10.3390/microorganisms10050879,Microorganisms. 2022 Apr 22;10(5):879,1120170077@mail.nankai.edu.cn,RpoE is induced by antibacterial peptides present in the blood and that it directly regulates many virulence genes,Y Fan 2022,2022,1 gene,"Fan-2022-RpoE Facilitates Stress-Resistance, I",BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20319,PHI:123199,UniProt,A0A2N6NM15,,,,,,BbPex1,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,peroxin,,,peroxisomal targeting signal pathway,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; sorbitol; H2O2; menadione; Congo red,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35736105,PubMed,10.3390/jof8060622,J Fungi (Basel). 2022 Jun 10;8(6):622,12107004@zju.edu.cn,Components of the receptor export complex link the peroxisomal function with fungal resistance to stress caused by polyunsaturated fatty acids,J Hou 2022,2022,3 genes,Hou-2022-Peroxins in Peroxisomal Receptor Expo,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20320,PHI:123200,UniProt,A0A2N6NGK6,,,,,,BbPex6,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,peroxin,,,peroxisomal targeting signal pathway,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; sorbitol; H2O2; menadione; Congo red,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35736105,PubMed,10.3390/jof8060622,J Fungi (Basel). 2022 Jun 10;8(6):622,12107004@zju.edu.cn,Components of the receptor export complex link the peroxisomal function with fungal resistance to stress caused by polyunsaturated fatty acids,J Hou 2022,2022,3 genes,Hou-2022-Peroxins in Peroxisomal Receptor Expo,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20321,PHI:123201,,no data found,,,,,,BbPex26,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,peroxin,,,peroxisomal targeting signal pathway,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; sorbitol; H2O2; menadione; Congo red,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35736105,PubMed,10.3390/jof8060622,J Fungi (Basel). 2022 Jun 10;8(6):622,12107004@zju.edu.cn,Components of the receptor export complex link the peroxisomal function with fungal resistance to stress caused by polyunsaturated fatty acids,J Hou 2022,2022,3 genes,Hou-2022-Peroxins in Peroxisomal Receptor Expo,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20322,PHI:123202,UniProt,J9VWZ9,GenBank,AFR97901,,,H99,CSN1201 (CNAG_01697),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,PCI domain-containing protein,,,,reduced virulence,,,,,,,,defective,,no,SDS; H2O2; sorbitol; NaCl; KCl; congo red,SDS: CHEBI:8984; H2O2: CHEBI:16240; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35720283,PubMed,10.3389/fimmu.2022.890258,Front Immunol. 2022 Jun 2;13:890258,weifang081782@163.com,A significant reduction (86.5% at 12 h and 92.5% at 24 h) was noted in the transcytosis efficiency of the csn1201 mutant,Y Yang 2022,2022,1 gene,Yang-2022-Cryptococcus neoformans Csn1201 Is A,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20323,PHI:123202,UniProt,J9VWZ9,GenBank,AFR97901,,,H99,CSN1201 (CNAG_01697),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,cryptococcosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; brain,PCI domain-containing protein,,,,reduced virulence,,,,,,,,defective,,no,SDS; H2O2; sorbitol; NaCl; KCl; congo red,SDS: CHEBI:8984; H2O2: CHEBI:16240; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35720283,PubMed,10.3389/fimmu.2022.890258,Front Immunol. 2022 Jun 2;13:890258,weifang081782@163.com,A significant reduction (86.5% at 12 h and 92.5% at 24 h) was noted in the transcytosis efficiency of the csn1201 mutant,Y Yang 2022,2022,1 gene,Yang-2022-Cryptococcus neoformans Csn1201 Is A,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20324,PHI:123203,UniProt,G1XC49,GenBank,EGX49463,,,ATCC 24927,AoGcs1 (AOL_s00078g496),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,ARF-GAP domain-containing protein,,,,reduced virulence,,,,,,defective,,reduced,wild type,no,SDS; H2O2; sorbitol; NaCl; congo red; menadione; rapamycin; H-89; tunicamycin; DTT,SDS: CHEBI:8984; H2O2: CHEBI:16240; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; congo red: CHEBI:34653; menadione: CHEBI:28869; rapamycin: CHEBI:9168; H-89: CHEBI:131488; tunicamycin: CHEBI:29699; DTT: CHEBI:42170,,,,,gene deletion: full,,,NN,35628718,PubMed,10.3390/jof8050463,J Fungi (Basel). 2022 Apr 29;8(5):463,yangle@mail.ynu.edu.cn,"These Arf-GAP proteins are involved in the regulation of DNA damage, endocytosis, ROS degradation, ER stress response, lipid storage, mitochondrial activity, and autophagy",L Yang,2022,2 genes,Yang-2022-The Arf-GAP Proteins AoGcs1 and AoGt,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20325,PHI:123204,UniProt,G1X9A5,GenBank,EGX50448,,,ATCC 24927,AoGts1 (AOL_s00076g212),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,ARF-GAP domain-containing protein,,,,reduced virulence,,,,,,defective,,reduced,reduced,no,SDS; H2O2; sorbitol; NaCl; congo red; menadione; rapamycin; H-89; tunicamycin; DTT,SDS: CHEBI:8984; H2O2: CHEBI:16240; sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; congo red: CHEBI:34653; menadione: CHEBI:28869; rapamycin: CHEBI:9168; H-89: CHEBI:131488; tunicamycin: CHEBI:29699; DTT: CHEBI:42170,,,,,gene deletion: full,,,NN,35628718,PubMed,10.3390/jof8050463,J Fungi (Basel). 2022 Apr 29;8(5):463,yangle@mail.ynu.edu.cn,"These Arf-GAP proteins are involved in the regulation of DNA damage, endocytosis, ROS degradation, ER stress response, lipid storage, mitochondrial activity, and autophagy",L Yang,2022,2 genes,Yang-2022-The Arf-GAP Proteins AoGcs1 and AoGt,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20326,PHI:123205,,no data found,GenBank,UOA05503,,,,PcERG3 (OM571178),,Transformant KE1-1,,,,,4784,Phytophthora capsici,,BYA5,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,C-5 sterol desaturase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,sorbitol; KCl; tebuconazole; prochloraz,sorbitol: CHEBI:30911; KCl: CHEBI:32588; tebuconazole: CHEBI:81781; prochloraz: CHEBI:8434,,,,,gene deletion: full,,,NN,35651492,PubMed,10.3389/fmicb.2022.811132,Front Microbiol. 2022 May 10;13:811132,seedling@cau.edu.cn,"The wild-type strain could convert stellasterol into the down-stream product while the transformant could not, indicating that PcErg3 retains theC-5 sterol desaturase activity.",W Wang 2022,2022,1 gene,Wang-2022-Functional Analysis of the C-5 Stero,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20327,PHI:123205,,no data found,GenBank,UOA05503,,,,PcERG3 (OM571178),,Transformant KE2-1,,,,,4784,Phytophthora capsici,,BYA5,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,C-5 sterol desaturase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,sorbitol; KCl; tebuconazole; prochloraz,sorbitol: CHEBI:30911; KCl: CHEBI:32588; tebuconazole: CHEBI:81781; prochloraz: CHEBI:8434,,,,,gene deletion: full,,,NN,35651492,PubMed,10.3389/fmicb.2022.811132,Front Microbiol. 2022 May 10;13:811132,seedling@cau.edu.cn,"The wild-type strain could convert stellasterol into the down-stream product while the transformant could not, indicating that PcErg3 retains theC-5 sterol desaturase activity.",W Wang 2022,2022,1 gene,Wang-2022-Functional Analysis of the C-5 Stero,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20328,PHI:123205,,no data found,GenBank,UOA05503,,,,PcERG3 (OM571178),,Transformant KE1-1,,,,,4784,Phytophthora capsici,,BYA5,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,C-5 sterol desaturase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,sorbitol; KCl; tebuconazole; prochloraz,sorbitol: CHEBI:30911; KCl: CHEBI:32588; tebuconazole: CHEBI:81781; prochloraz: CHEBI:8434,,,,,gene deletion: full,,,NN,35651492,PubMed,10.3389/fmicb.2022.811132,Front Microbiol. 2022 May 10;13:811132,seedling@cau.edu.cn,"The wild-type strain could convert stellasterol into the down-stream product while the transformant could not, indicating that PcErg3 retains theC-5 sterol desaturase activity.",W Wang 2022,2022,1 gene,Wang-2022-Functional Analysis of the C-5 Stero,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20329,PHI:123205,,no data found,GenBank,UOA05503,,,,PcERG3 (OM571178),,Transformant KE2-1,,,,,4784,Phytophthora capsici,,BYA5,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,C-5 sterol desaturase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,sorbitol; KCl; tebuconazole; prochloraz,sorbitol: CHEBI:30911; KCl: CHEBI:32588; tebuconazole: CHEBI:81781; prochloraz: CHEBI:8434,,,,,gene deletion: full,,,NN,35651492,PubMed,10.3389/fmicb.2022.811132,Front Microbiol. 2022 May 10;13:811132,seedling@cau.edu.cn,"The wild-type strain could convert stellasterol into the down-stream product while the transformant could not, indicating that PcErg3 retains theC-5 sterol desaturase activity.",W Wang 2022,2022,1 gene,Wang-2022-Functional Analysis of the C-5 Stero,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20330,PHI:123206,UniProt,G4MY57,GenBank,EHA54388,,,70-15,Mowhi2 (MGG_11241),chromosome 2,,,,,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf sheath,general stress response protein,,,mitophagy pathway,reduced virulence,,,,,,defective,,defective,,no,,,,,,,gene deletion: full,,,NN,35628129,PubMed,10.3390/ijms23105311,Int J Mol Sci. 2022 May 10;23(10):5311,mengrice@163.com,MoWhi2 is specifically required for mitophagy in M. oryzae,S Meng 2022,2022,1 gene,Meng-2022-MoWhi2 Mediates Mitophagy to Regulat,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20331,PHI:123207,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,extent of cell elongation protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35612314,PubMed,10.1128/spectrum.02630-21,Microbiol Spectr. 2022 Jun 29;10(3):e0263021,brian.peters@uthsc.edu.,,J Liu 2022,2022,1 gene,Liu-2022-Rapid Hypothesis Testing in Candida a,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20332,PHI:123207,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,529L,candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,extent of cell elongation protein 1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35612314,PubMed,10.1128/spectrum.02630-21,Microbiol Spectr. 2022 Jun 29;10(3):e0263021,brian.peters@uthsc.edu.,,J Liu 2022,2022,1 gene,Liu-2022-Rapid Hypothesis Testing in Candida a,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20333,PHI:123207,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,JS15,candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,extent of cell elongation protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35612314,PubMed,10.1128/spectrum.02630-21,Microbiol Spectr. 2022 Jun 29;10(3):e0263021,brian.peters@uthsc.edu.,,J Liu 2022,2022,1 gene,Liu-2022-Rapid Hypothesis Testing in Candida a,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20334,PHI:123207,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,SJCA1,candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,extent of cell elongation protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35612314,PubMed,10.1128/spectrum.02630-21,Microbiol Spectr. 2022 Jun 29;10(3):e0263021,brian.peters@uthsc.edu.,,J Liu 2022,2022,1 gene,Liu-2022-Rapid Hypothesis Testing in Candida a,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20335,PHI:123207,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,TW1,candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,extent of cell elongation protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35612314,PubMed,10.1128/spectrum.02630-21,Microbiol Spectr. 2022 Jun 29;10(3):e0263021,brian.peters@uthsc.edu.,,J Liu 2022,2022,1 gene,Liu-2022-Rapid Hypothesis Testing in Candida a,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20336,PHI:123208,UniProt,P63798,GenBank,AAL20657,,,LT2,clsA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; liver; bone marrow-derived macrophage,cardiolipin synthase A,,,,unaffected pathogenicity,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,three CL synthase genes cooperatively and redundantly influence S.Typhimurium inflammasome activation and intracellular survival in C57BL/6J mouse macrophages but are dispensable for virulence in mice,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20337,PHI:123209,UniProt,Q8ZQP4,GenBank,AAL19749,,,LT2,clsB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; liver; bone marrow-derived macrophage,cardiolipin synthase B,,,,unaffected pathogenicity,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,three CL synthase genes cooperatively and redundantly influence S.Typhimurium inflammasome activation and intracellular survival in C57BL/6J mouse macrophages but are dispensable for virulence in mice,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20338,PHI:123210,UniProt,Q8ZQ28,GenBank,AAL20078,,,LT2,clsC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; liver; bone marrow-derived macrophage,cardiolipin synthase C,,,,unaffected pathogenicity,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,three CL synthase genes cooperatively and redundantly influence S.Typhimurium inflammasome activation and intracellular survival in C57BL/6J mouse macrophages but are dispensable for virulence in mice,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20339,PHI:123208,UniProt,P63798,GenBank,AAL20657,,,LT2,clsA,,,,,,PHI:123209; PHI:123210,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; liver,cardiolipin synthase A,,,,unaffected pathogenicity,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,Mouse infected intraperitoneally,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20340,PHI:123209,UniProt,Q8ZQP4,GenBank,AAL19749,,,LT2,clsB,,,,,,PHI:123208; PHI:123210,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; liver,cardiolipin synthase B,,,,unaffected pathogenicity,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,Mouse infected intraperitoneally,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20341,PHI:123210,UniProt,Q8ZQ28,GenBank,AAL20078,,,LT2,clsC,,,,,,PHI:123208; PHI:123209,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; liver,cardiolipin synthase C,,,,unaffected pathogenicity,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,Mouse infected intraperitoneally,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20342,PHI:123208,UniProt,P63798,GenBank,AAL20657,,,LT2,clsA,,,,,,PHI:123209; PHI:123210,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; liver; bone marrow-derived macrophage,cardiolipin synthase A,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,Mouse infected orally,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20343,PHI:123209,UniProt,Q8ZQP4,GenBank,AAL19749,,,LT2,clsB,,,,,,PHI:123208; PHI:123210,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; liver; bone marrow-derived macrophage,cardiolipin synthase B,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,Mouse infected orally,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20344,PHI:123210,UniProt,Q8ZQ28,GenBank,AAL20078,,,LT2,clsC,,,,,,PHI:123208; PHI:123209,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; liver; bone marrow-derived macrophage,cardiolipin synthase C,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,Mouse infected orally,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20345,PHI:123208,UniProt,P63798,GenBank,AAL20657,,,LT2,clsA,,,,,,PHI:123209,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,cardiolipin synthase A,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,three CL synthase genes cooperatively and redundantly influence S.Typhimurium inflammasome activation and intracellular survival in C57BL/6J mouse macrophages but are dispensable for virulence in mice,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20346,PHI:123209,UniProt,Q8ZQP4,GenBank,AAL19749,,,LT2,clsB,,,,,,PHI:123208,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,cardiolipin synthase B,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,three CL synthase genes cooperatively and redundantly influence S.Typhimurium inflammasome activation and intracellular survival in C57BL/6J mouse macrophages but are dispensable for virulence in mice,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20347,PHI:123209,UniProt,Q8ZQP4,GenBank,AAL19749,,,LT2,clsB,,,,,,PHI:123210,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,cardiolipin synthase B,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,three CL synthase genes cooperatively and redundantly influence S.Typhimurium inflammasome activation and intracellular survival in C57BL/6J mouse macrophages but are dispensable for virulence in mice,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20348,PHI:123210,UniProt,Q8ZQ28,GenBank,AAL20078,,,LT2,clsC,,,,,,PHI:123209,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,cardiolipin synthase C,,,,reduced virulence,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,three CL synthase genes cooperatively and redundantly influence S.Typhimurium inflammasome activation and intracellular survival in C57BL/6J mouse macrophages but are dispensable for virulence in mice,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20349,PHI:123208,UniProt,P63798,GenBank,AAL20657,,,LT2,clsA,,,,,,PHI:123210,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,cardiolipin synthase A,,,,unaffected pathogenicity,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,three CL synthase genes cooperatively and redundantly influence S.Typhimurium inflammasome activation and intracellular survival in C57BL/6J mouse macrophages but are dispensable for virulence in mice,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20350,PHI:123210,UniProt,Q8ZQ28,GenBank,AAL20078,,,LT2,clsC,,,,,,PHI:123208,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,cardiolipin synthase C,,,,unaffected pathogenicity,,,,,,,,,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full,,,NN,35638781,PubMed,10.1128/spectrum.02617-21,Microbiol Spectr. 2022 Jun 29;10(3):e0261721,zdalebro@ouhsc.edu.,three CL synthase genes cooperatively and redundantly influence S.Typhimurium inflammasome activation and intracellular survival in C57BL/6J mouse macrophages but are dispensable for virulence in mice,M B Cian 2022,2022,3 genes,Cian-2022-Cardiolipin Biosynthesis Genes Are N,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20351,PHI:123211,,no data found,GenBank,AKO16095,,,RS105,VemR (ACU12_10515),,D56 was substituted with a neutral amino acid Val (V),,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial leaf streak,monocots,4530,Oryza sativa (related: rice),cv. Shangyou 63,,,leaf,response regulator,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35756024,PubMed,10.3389/fmicb.2022.928551,Front Microbiol. 2022 Jun 9;13:928551,gyouchen@sjtu.edu.cn,Site-directed mutagenesis and phosphotransfer experiments revealed that the conserved aspartate (D56) residue within the stand-alone phosphoacceptor receiver (REC) domain is essential for phosphorelay and the regulatory activity of Xoc VemR,L Cai 2022,2022,4 genes,Cai-2022-Xanthomonas oryzae Pv. oryzicola Resp,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20352,PHI:123211,,no data found,GenBank,AKO16095,,,RS105,VemR (ACU12_10515),,D56 was substituted with a neutral amino acid Val (V),,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial leaf streak,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,response regulator,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35756024,PubMed,10.3389/fmicb.2022.928551,Front Microbiol. 2022 Jun 9;13:928551,gyouchen@sjtu.edu.cn,Site-directed mutagenesis and phosphotransfer experiments revealed that the conserved aspartate (D56) residue within the stand-alone phosphoacceptor receiver (REC) domain is essential for phosphorelay and the regulatory activity of Xoc VemR,L Cai 2022,2022,4 genes,Cai-2022-Xanthomonas oryzae Pv. oryzicola Resp,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20353,PHI:123212,,no data found,GenBank,AKO15627,,,RS105,sucA (ACU12_07715),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial leaf streak,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,oxoglutarate dehydrogenase (succinyl-transferring),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35756024,PubMed,10.3389/fmicb.2022.928551,Front Microbiol. 2022 Jun 9;13:928551,gyouchen@sjtu.edu.cn,Site-directed mutagenesis and phosphotransfer experiments revealed that the conserved aspartate (D56) residue within the stand-alone phosphoacceptor receiver (REC) domain is essential for phosphorelay and the regulatory activity of Xoc VemR,L Cai 2022,2022,4 genes,Cai-2022-Xanthomonas oryzae Pv. oryzicola Resp,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20354,PHI:123213,,no data found,GenBank,AKO15937,,,RS105,sirA (ACU12_09595),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial leaf streak,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35756024,PubMed,10.3389/fmicb.2022.928551,Front Microbiol. 2022 Jun 9;13:928551,gyouchen@sjtu.edu.cn,Site-directed mutagenesis and phosphotransfer experiments revealed that the conserved aspartate (D56) residue within the stand-alone phosphoacceptor receiver (REC) domain is essential for phosphorelay and the regulatory activity of Xoc VemR,L Cai 2022,2022,4 genes,Cai-2022-Xanthomonas oryzae Pv. oryzicola Resp,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20355,PHI:123214,,no data found,GenBank,AKO16075,,,RS105,flgA (ACU12_10415),,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain RS105,bacterial leaf streak,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,flagella basal body P-ring formation protein FlgA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35756024,PubMed,10.3389/fmicb.2022.928551,Front Microbiol. 2022 Jun 9;13:928551,gyouchen@sjtu.edu.cn,Site-directed mutagenesis and phosphotransfer experiments revealed that the conserved aspartate (D56) residue within the stand-alone phosphoacceptor receiver (REC) domain is essential for phosphorelay and the regulatory activity of Xoc VemR,L Cai 2022,2022,4 genes,Cai-2022-Xanthomonas oryzae Pv. oryzicola Resp,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20356,PHI:123215,UniProt,Q9K5C7,GenBank,CAA44467,,,NCPPB 382,celA,,,,,,,28447,Clavibacter michiganensis,,LMG 7333T,bacterial canker,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,cellulase,,,,unaffected pathogenicity,,,,,blister-like lesions; necrosis; delayed wilting,,,,,no,,,,,,,gene mutation,,,NN,35620684,PubMed,10.3389/fpls.2022.876971,Front Plant Sci. 2022 May 10;13:876971,co35@khu.ac.kr,N. benthamiana is a surrogate host of C. michiganensis and C. capsici and N. tabacum is a non-host plant of both Clavibacter species,I W Park 2022,2022,2 genes,"Park-2022-Nicotiana benthamiana, a Surrogate H",BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20357,PHI:123216,UniProt,A5CLR7,GenBank,CAM98538,,,NCPPB 382,pat-1,,,,,,,28447,Clavibacter michiganensis,,LMG 7333T,bacterial canker,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,putative serine protease,,,,unaffected pathogenicity,,,,,blister-like lesions; necrosis; delayed wilting,,,,,no,,,,,,,gene mutation,,,NN,35620684,PubMed,10.3389/fpls.2022.876971,Front Plant Sci. 2022 May 10;13:876971,co35@khu.ac.kr,N. benthamiana is a surrogate host of C. michiganensis and C. capsici and N. tabacum is a non-host plant of both Clavibacter species,I W Park 2022,2022,2 genes,"Park-2022-Nicotiana benthamiana, a Surrogate H",BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20358,PHI:123215,UniProt,Q9K5C7,GenBank,CAA44467,,,NCPPB 382,celA,,,,,,,28447,Clavibacter michiganensis,,LMG 7333T,bacterial canker,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,cellulase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35620684,PubMed,10.3389/fpls.2022.876971,Front Plant Sci. 2022 May 10;13:876971,co35@khu.ac.kr,N. benthamiana is a surrogate host of C. michiganensis and C. capsici and N. tabacum is a non-host plant of both Clavibacter species,I W Park 2022,2022,2 genes,"Park-2022-Nicotiana benthamiana, a Surrogate H",BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20359,PHI:123216,UniProt,A5CLR7,GenBank,CAM98538,,,NCPPB 382,pat-1,,,,,,,28447,Clavibacter michiganensis,,LMG 7333T,bacterial canker,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,putative serine protease,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35620684,PubMed,10.3389/fpls.2022.876971,Front Plant Sci. 2022 May 10;13:876971,co35@khu.ac.kr,N. benthamiana is a surrogate host of C. michiganensis and C. capsici and N. tabacum is a non-host plant of both Clavibacter species,I W Park 2022,2022,2 genes,"Park-2022-Nicotiana benthamiana, a Surrogate H",BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20360,PHI:123217,UniProt,O42720,GenBank,AAC39354,,,G186AR,cbp1,,,,,,,5037,Histoplasma capsulatum,,G217B ura54Δ,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,calcium binding protein 1,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,gene mutation,,,NN,35731824,PubMed,10.1371/journal.ppat.1010417,PLoS Pathog. 2022 Jun 22;18(6):e1010417,sil@cgl.ucsf.edu,"Despite the con-servation of Cbp1 homologs in the genomes of Emergomyces species, these proteins were unlikethe Pb03 Cbp1 in that they could not restore lysis during Hc infection.",D Azimova 2022,2022,2 genes,"Azimova-2022-Cbp1, a fungal virulence factor u",BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20361,PHI:123218,UniProt,Q00950,GenBank,AAA33384,,,G217B,yps-3,,,,,,,5037,Histoplasma capsulatum,,G217B ura54Δ,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage,yeast phase specific protein,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,gene mutation; gene complementation,,,NN,35731824,PubMed,10.1371/journal.ppat.1010417,PLoS Pathog. 2022 Jun 22;18(6):e1010417,sil@cgl.ucsf.edu,"Despite the con-servation of Cbp1 homologs in the genomes of Emergomyces species, these proteins were unlikethe Pb03 Cbp1 in that they could not restore lysis during Hc infection.",D Azimova 2022,2022,2 genes,"Azimova-2022-Cbp1, a fungal virulence factor u",BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20362,PHI:123219,UniProt,A0A2H3GEQ4,GenBank,ESU06709,,,PH-1; NRRL 31084,FgErv14 (FGSG_01398),chromosome 1,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,endoplasmic reticulum cargo receptor,,,,reduced virulence,,,,,reduced lesions,reduced,defective,defective,defective,no,NaCl; sorbitol; SDS; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:17924; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35743830,PubMed,10.3390/life12060799,Life (Basel). 2022 May 27;12(6):799,2020110381@sdau.edu.cn,FgErv14 mediates anterograde ER-to-Golgi transport as well as late secretory Golgi-to-Plasma membrane transport and is necessary for DON biosynthesis. Issue 'flowering wheat spikelets'.,F Sun 2022,2022,1 gene,Sun-2022-The Endoplasmic Reticulum Cargo Recep,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20363,PHI:123220,,no data found,,,,,,hopAZ1a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20364,PHI:123221,,no data found,,,,,,hopD1a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20365,PHI:123222,,no data found,,,,,,hopS2b,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20366,PHI:123223,,no data found,,,,,,hopR1b,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20367,PHI:123224,,no data found,,,,,,hopY1b,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20368,PHI:123225,,no data found,,,,,,hopAu1a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20369,PHI:123226,,no data found,,,,,,avrPto1b,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20370,PHI:123227,,no data found,,,,,,hopW1c,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20371,PHI:123228,,no data found,,,,,,hopAM1a_1,,,,,,PHI:123229,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20372,PHI:123229,,no data found,,,,,,hopAM1a_2,,,,,,PHI:123228,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20373,PHI:123230,UniProt,Q887D0,GenBank,AF232006_4,,,DC3000,CEL,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20374,PHI:123231,,no data found,,,,,,hopBP1a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20375,PHI:123232,,no data found,,,,,,hopBN1a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20376,PHI:123233,,no data found,,,,,,hopF1c,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20377,PHI:123234,,no data found,,,,,,hopQ1a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20378,PHI:123235,,no data found,,,,,,avrRpm1a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20379,PHI:123236,,no data found,,,,,,hopZ5a,,,,,,PHI:123237,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20380,PHI:123237,,no data found,,,,,,hopH1a,,,,,,PHI:123236,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20381,PHI:123238,,no data found,,,,,,hopI1c,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20382,PHI:123239,,no data found,,,,,,hopAS1b,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20383,PHI:123240,,no data found,,,,,,hopAW1a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20384,PHI:123240,,no data found,,,,,,hopAW1a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20385,PHI:123231,,no data found,,,,,,hopF1c,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20386,PHI:123234,,no data found,,,,,,hopZ5a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20387,PHI:123233,,no data found,,,,,,avrRpm1a,,,,,,,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20388,PHI:123231,,no data found,,,,,,hopF1c,,,,,,PHI:123240,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20389,PHI:123240,,no data found,,,,,,hopAW1a,,,,,,PHI:123233,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20390,PHI:123231,,no data found,,,,,,hopF1c,,,,,,PHI:123240; PHI:123235,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20391,PHI:123240,,no data found,,,,,,hopAW1a,,,,,,PHI:123233; PHI:123235,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20392,PHI:123233,,no data found,,,,,,avrRpm1a,,,,,,PHI:123233; PHI:123240,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20393,PHI:123231,,no data found,,,,,,hopF1c,,,,,,PHI:123240; PHI:123235; PHI:123236,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20394,PHI:123240,,no data found,,,,,,hopAW1a,,,,,,PHI:123233; PHI:123235; PHI:123236,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20395,PHI:123233,,no data found,,,,,,avrRpm1a,,,,,,PHI:123233; PHI:123240; PHI:123236,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20396,PHI:123234,,no data found,,,,,,hopZ5a,,,,,,PHI:123233; PHI:123240; PHI:123235,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,64478,Actinidia arguta (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20397,PHI:123231,,no data found,,,,,,hopF1c,,,,,,PHI:123240,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20398,PHI:123240,,no data found,,,,,,hopAW1a,,,,,,PHI:123233,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20399,PHI:123231,,no data found,,,,,,hopF1c,,,,,,PHI:123240; PHI:123235,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20400,PHI:123240,,no data found,,,,,,hopAW1a,,,,,,PHI:123233; PHI:123235,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20401,PHI:123233,,no data found,,,,,,avrRpm1a,,,,,,PHI:123233; PHI:123240,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20402,PHI:123231,,no data found,,,,,,hopF1c,,,,,,PHI:123240; PHI:123235; PHI:123236,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20403,PHI:123240,,no data found,,,,,,hopAW1a,,,,,,PHI:123233; PHI:123235; PHI:123236,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20404,PHI:123233,,no data found,,,,,,avrRpm1a,,,,,,PHI:123233; PHI:123240; PHI:123236,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20405,PHI:123234,,no data found,,,,,,hopZ5a,,,,,,PHI:123233; PHI:123240; PHI:123235,317,Pseudomonas syringae,,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35622878,PubMed,10.1371/journal.ppat.1010542,PLoS Pathog. 2022 May 27;18(5):e1010542,matt.templeton@plantandfood.co.nz,"Psa3 effector knockout strains identified increased growth in planta for knock-outs of four effectors–AvrRpm1a, HopF1c, HopZ5a, and the EEL effector HopAW1a -suggesting a resistance response in A. arguta.",L M Hemara 2022,2022,21 genes,Hemara-2022-Effector loss drives adaptation of,BATCH_113A,2022-07-01,MC,,,,,,,,,,,,,
,,Record 20406,PHI:123235,,no data found,,,,,,hxtR (B9H01_RS05155),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,XRE family transcriptional regulator,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,ΔhxtR showed a significant decrease in virulence in the G. mellonella larvae infection assay,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20407,PHI:123235,,no data found,,,,,,hxtR (B9H01_RS05155),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",rodents,10090,Mus musculus (related: house mouse),Kunming,,,,XRE family transcriptional regulator,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,ΔhxtR showed a significant decrease in virulence in the mouse infection assay,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20408,PHI:123235,,no data found,,,,,,hxtR (B9H01_RS05155),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,,XRE family transcriptional regulator,,,,reduced virulence,,,,,,,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,"In the phagocytosis assay, compared to the SC19 strain, the hxtR deletion mutant strain was much easier to be phagocytized by the macrophage cells.",J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20409,PHI:123236,UniProt,A4VXV9,GenBank,ABP90948,,,05ZYH33,SspA (B9H01_RS03990),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,subtilisin-like serine protease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20410,PHI:123237,UniProt,Q8GG78,GenBank,AAN76309,,,I9841/1,ArcC (B9H01_RS03140),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,carbamate kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20411,PHI:123238,UniProt,A0A0M9FFE8,GenBank,BCK45280,,,DAT300,ciaR (B9H01_RS04445),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DNA-binding response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20412,PHI:123239,UniProt,A0A426G9B7,GenBank,RRN51629,,,IMT40201,EI219_00650 (B9H01_RS07420),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,voltage-gated chloride channel protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20413,PHI:123240,UniProt,A0A0Z8W2G3,GenBank,RRN48481,,,IMT40738,rgpD (B9H01_RS04375),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,ABC transporter ATP-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20414,PHI:123241,UniProt,A0A0Z8HI77,GenBank,CYU25412,,,LSS32,ugpA_2 (B9H01_RS00985),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sugar ABC transporter permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20415,PHI:123242,UniProt,A0A6L8MWN2,GenBank,MYN69560,,,10-36905,PFL (B9H01_RS01125),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,formate C-acetyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20416,PHI:123243,,no data found,,,,,,peptidase (B9H01_RS05230),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,peptidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20417,PHI:123244,UniProt,A0A7G1JTF3,GenBank,BCK45272,,,DAT300,DAT300_08110 (B9H01_RS05380),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,SAM-dependent methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20418,PHI:123245,UniProt,A0A2I7ZF20,GenBank,AUS90997,,,1439272,AUS90997 (B9H01_RS07385),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,site-specific integrase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20419,PHI:123246,UniProt,A0A3R8MZL7,GenBank,RRN48729,,,IMT40201,EI219_09440 (B9H01_RS04890),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DUF1836 domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20420,PHI:123247,UniProt,A0A4V0EW10,GenBank,VTT12277,,,NCTC10446,murAA (B9H01_RS05665),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,UDP-N-acetylglucosamine 1-carboxyvinyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20421,PHI:123248,UniProt,A0A4V0ETS4,GenBank,VTT12284,,,NCTC10446,uidA (B9H01_RS05640),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,beta-glucuronidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20422,PHI:123249,UniProt,E3UN55,GenBank,ADO66679,,,HA1001111,hylA (B9H01_RS05870),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,hyaluronidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20423,PHI:123250,UniProt,A0A6L8N060,GenBank,MYN70663,,,10-36905,GLP18_10670 (B9H01_RS04330),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,phosphomannomutase/phosphoglucomutase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20424,PHI:123251,,no data found,GenBank,AMU80190,,,90-1330,B9H01_RS10315,,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,glycosyl hydrolase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20425,PHI:123252,UniProt,A0A7G1JLM6,GenBank,BCK43195,,,DAT299,B9H01_RS05605,,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,beta-hexosamidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20426,PHI:123253,UniProt,A0A2S2F5T3,GenBank,AWL26280,,,HN105,B9H01_RS03375,,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,DUF975 domain-containing protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20427,PHI:123254,UniProt,A0A3R8N054,GenBank,RRN50422,,,IMT40738,glgB (B9H01_RS04990),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"1,4-alpha-glucan branching protein",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20428,PHI:123255,,no data found,GenBank,UUM61688,,,DNC13,B9H01_RS05160,,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,A/G-specific adenine glycosylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20429,PHI:123256,UniProt,A0A2I7ZEX1,GenBank,AUS90958,,,1439272,B9H01_RS04765,,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,glucan-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20430,PHI:123257,,no data found,GenBank,ANJ64477,,,05SC260,B9H01_RS05135,,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,integrase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20431,PHI:123258,UniProt,A0A0Z8K990,GenBank,BCK44638,,,DAT300,PulG (B9H01_RS00820),,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,"type II secretion pathway, pseudopilin",,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20432,PHI:123259,UniProt,AA0A7G1JTG2,GenBank,BCK44831,,,DAT300,B9H01_RS06130,,,,,,,1307,Streptococcus suis,391295,SC19,"meningitis, endocarditis; sepsis",moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histidine triad protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35630313,PubMed,10.3390/microorganisms10050868,Microorganisms. 2022 Apr 21;10(5):868,qhuang@mail.hzau.edu.cn,A transposon mutant library showed 32 mutants which caused reduction in virulence of Streptococcus suis in Galleria mellonella larvae infection model.,J Fan 2022,2022,25 genes,Fan-2022-Screening for Virulence-Related Genes,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20433,PHI:123260,UniProt,P29485,GenBank,CAA45453,,,"ssp. classical 01, Z17561",TcpP,,Ptac-tcpPH,,,,,666,Vibrio cholerae,,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine,toxin coregulated pilus biosynthesis protein P,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation,,,NN,35714156,PubMed,10.1371/journal.ppat.1010581,PLoS Pathog. 2022 Jun 17;18(6):e1010581,junzhu@pennmedicine.upenn.edu,The viability of Ptac-tcpPH strains was significantly reduced.,J Chen 2022,2022,3 genes,Chen-2022-S-Nitrosylation of the virulence reg,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20434,PHI:123261,UniProt,Q9XC54,GenBank,AAD45271,,,,aphB,,C235S,,,,,666,Vibrio cholerae,,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine,AphB and OhrR monitor redox-potential changes and respond with different kinetics,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation: characterised,,,NN,35714156,PubMed,10.1371/journal.ppat.1010581,PLoS Pathog. 2022 Jun 17;18(6):e1010581,junzhu@pennmedicine.upenn.edu,"When the non-modifiable aphB C235S mutants were tested in mouse model, the-AG group, aphB C235S mutants had an approximately 1000-fold reduction in colonization compared to the wildtype.",J Chen 2022,2022,3 genes,Chen-2022-S-Nitrosylation of the virulence reg,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20435,PHI:123262,UniProt,Q30K37,GenBank,AAY87589,,,,hmpA,,,,,,,666,Vibrio cholerae,,El Tor C6706,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,small intestine,AphB and OhrR monitor redox-potential changes and respond with different kinetics,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35714156,PubMed,10.1371/journal.ppat.1010581,PLoS Pathog. 2022 Jun 17;18(6):e1010581,junzhu@pennmedicine.upenn.edu,ΔhmpA mutants displayed a significant colonization defect in both the small intestine,J Chen 2022,2022,3 genes,Chen-2022-S-Nitrosylation of the virulence reg,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20436,PHI:123263,UniProt,A0A8F5VTG7,GenBank,QXO97734,,,HS-18,aigA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,3712,Brassica oleracea (no common name found),,,,leaf,acyl-homoserine-lactone acylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35708354,PubMed,10.1099/mic.0.000778,J Agric Food Chem. 2022 Jun 29;70(25):7716-7726,lishengliao@scau.edu.cn,aigA from Pseudomonas sp. strain HS-18 was heterologously expressed in Pseudomonas aeruginosa PAO1 strain which showed imparied pathogenicity in cabbage and lettuce.,H Wang 2022,2022,3 genes,Wang-2022-A Bacterial Isolate Capable of Quenc,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20437,PHI:123263,UniProt,A0A8F5VTG7,GenBank,QXO97734,,,HS-18,aigA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,acyl-homoserine-lactone acylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35708354,PubMed,10.1099/mic.0.000778,J Agric Food Chem. 2022 Jun 29;70(25):7716-7726,lishengliao@scau.edu.cn,aigA from Pseudomonas sp. strain HS-18 was heterologously expressed in Pseudomonas aeruginosa PAO1 strain which showed imparied pathogenicity in cabbage and lettuce.,H Wang 2022,2022,3 genes,Wang-2022-A Bacterial Isolate Capable of Quenc,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20438,PHI:123264,UniProt,A0A8F5VS00,GenBank,QXO97735,,,HS-18,aigB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,3712,Brassica oleracea (no common name found),,,,leaf,acyl-homoserine-lactone acylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35708354,PubMed,10.1099/mic.0.000778,J Agric Food Chem. 2022 Jun 29;70(25):7716-7726,lishengliao@scau.edu.cn,aigB from Pseudomonas sp. strain HS-18 was heterologously expressed in Pseudomonas aeruginosa PAO1 strain which showed imparied pathogenicity in cabbage and lettuce.,H Wang 2022,2022,3 genes,Wang-2022-A Bacterial Isolate Capable of Quenc,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20439,PHI:123264,UniProt,A0A8F5VS00,GenBank,QXO97735,,,HS-18,aigB,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,acyl-homoserine-lactone acylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35708354,PubMed,10.1099/mic.0.000778,J Agric Food Chem. 2022 Jun 29;70(25):7716-7726,lishengliao@scau.edu.cn,aigB from Pseudomonas sp. strain HS-18 was heterologously expressed in Pseudomonas aeruginosa PAO1 strain which showed imparied pathogenicity in cabbage and lettuce.,H Wang 2022,2022,3 genes,Wang-2022-A Bacterial Isolate Capable of Quenc,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20440,PHI:123265,UniProt,A0A8F5VT34,GenBank,QXO97736,,,HS-18,aigC,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,3712,Brassica oleracea (no common name found),,,,leaf,acyl-homoserine-lactone acylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35708354,PubMed,10.1099/mic.0.000778,J Agric Food Chem. 2022 Jun 29;70(25):7716-7726,lishengliao@scau.edu.cn,aigC from Pseudomonas sp. strain HS-18 was heterologously expressed in Pseudomonas aeruginosa PAO1 strain which showed imparied pathogenicity in cabbage and lettuce.,H Wang 2022,2022,3 genes,Wang-2022-A Bacterial Isolate Capable of Quenc,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20441,PHI:123265,UniProt,A0A8F5VT34,GenBank,QXO97736,,,HS-18,aigC,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,acyl-homoserine-lactone acylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35708354,PubMed,10.1099/mic.0.000778,J Agric Food Chem. 2022 Jun 29;70(25):7716-7726,lishengliao@scau.edu.cn,aigC from Pseudomonas sp. strain HS-18 was heterologously expressed in Pseudomonas aeruginosa PAO1 strain which showed imparied pathogenicity in cabbage and lettuce.,H Wang 2022,2022,3 genes,Wang-2022-A Bacterial Isolate Capable of Quenc,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20442,PHI:123263,UniProt,A0A8F5VTG7,GenBank,QXO97734,,,HS-18,aigA,,,,,,,95486,Burkholderia cenocepacia,985075,H111,infection,monocots,4679,Allium cepa (related: onion),,,,bulb,acyl-homoserine-lactone acylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35708354,PubMed,10.1099/mic.0.000778,J Agric Food Chem. 2022 Jun 29;70(25):7716-7726,lishengliao@scau.edu.cn,aigA from Pseudomonas sp. strain HS-18 was heterologously expressed in Burkholderia cenocepacia H111 strain which showed imparied pathogenicity in onion.,H Wang 2022,2022,3 genes,Wang-2022-A Bacterial Isolate Capable of Quenc,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20443,PHI:123264,UniProt,A0A8F5VS00,GenBank,QXO97735,,,HS-18,aigB,,,,,,,95486,Burkholderia cenocepacia,985075,H111,infection,monocots,4679,Allium cepa (related: onion),,,,bulb,acyl-homoserine-lactone acylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35708354,PubMed,10.1099/mic.0.000778,J Agric Food Chem. 2022 Jun 29;70(25):7716-7726,lishengliao@scau.edu.cn,aigB from Pseudomonas sp. strain HS-18 was heterologously expressed in Burkholderia cenocepacia H111 strain which showed imparied pathogenicity in onion.,H Wang 2022,2022,3 genes,Wang-2022-A Bacterial Isolate Capable of Quenc,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20444,PHI:123265,UniProt,A0A8F5VT34,GenBank,QXO97736,,,HS-18,aigC,,,,,,,95486,Burkholderia cenocepacia,985075,PAO1,infection,monocots,4679,Allium cepa (related: onion),,,,bulb,acyl-homoserine-lactone acylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35708354,PubMed,10.1099/mic.0.000778,J Agric Food Chem. 2022 Jun 29;70(25):7716-7726,lishengliao@scau.edu.cn,aigC from Pseudomonas sp. strain HS-18 was heterologously expressed in Burkholderia cenocepacia H111 strain which showed imparied pathogenicity in onion.,H Wang 2022,2022,3 genes,Wang-2022-A Bacterial Isolate Capable of Quenc,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20445,PHI:123266,UniProt,A0A550KY48,GenBank,TGB21132,,,Y3X,ntrB,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,"nitrate ABC transporter, permease protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,NN,35637237,PubMed,10.1038/s41598-022-12650-2,Sci Rep. 2022 May 30;12(1):9027,bob@hancocklab.com,Coinfected with S. aureus USA300 LAC,M A Alford 2022,2022,2 genes,Alford-2022-Competition between Pseudomonas ae,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20446,PHI:123267,UniProt,A6VDP3,GenBank,ABR83279,,,PA7,ntrC,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,DNA-binding transcriptional regulator NtrC,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,NN,35637237,PubMed,10.1038/s41598-022-12650-2,Sci Rep. 2022 May 30;12(1):9027,bob@hancocklab.com,Coinfected with S. aureus USA300 LAC,M A Alford 2022,2022,2 genes,Alford-2022-Competition between Pseudomonas ae,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20447,PHI:123266,UniProt,A0A550KY48,GenBank,TGB21132,,,Y3X,ntrB,,,,,,PHI:123267,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,"nitrate ABC transporter, permease protein",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,35637237,PubMed,10.1038/s41598-022-12650-2,Sci Rep. 2022 May 30;12(1):9027,bob@hancocklab.com,Coinfected with S. aureus USA300 LAC,M A Alford 2022,2022,2 genes,Alford-2022-Competition between Pseudomonas ae,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20448,PHI:123267,UniProt,A6VDP3,GenBank,ABR83279,,,PA7,ntrC,,,,,,PHI:123266,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,DNA-binding transcriptional regulator NtrC,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,35637237,PubMed,10.1038/s41598-022-12650-2,Sci Rep. 2022 May 30;12(1):9027,bob@hancocklab.com,Coinfected with S. aureus USA300 LAC,M A Alford 2022,2022,2 genes,Alford-2022-Competition between Pseudomonas ae,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20449,PHI:123266,UniProt,A0A550KY48,GenBank,TGB21132,,,Y3X,ntrB,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,primates,9606,Homo sapiens (related: human),Ker-CT cell line,,,keratinocyte,"nitrate ABC transporter, permease protein",,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,NN,35637237,PubMed,10.1038/s41598-022-12650-2,Sci Rep. 2022 May 30;12(1):9027,bob@hancocklab.com,Coinfected with S. aureus USA300 LAC,M A Alford 2022,2022,2 genes,Alford-2022-Competition between Pseudomonas ae,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20450,PHI:123267,UniProt,A6VDP3,GenBank,ABR83279,,,PA7,ntrC,,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,primates,9606,Homo sapiens (related: human),Ker-CT cell line,,,keratinocyte,DNA-binding transcriptional regulator NtrC,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,NN,35637237,PubMed,10.1038/s41598-022-12650-2,Sci Rep. 2022 May 30;12(1):9027,bob@hancocklab.com,Coinfected with S. aureus USA300 LAC,M A Alford 2022,2022,2 genes,Alford-2022-Competition between Pseudomonas ae,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20451,PHI:123266,UniProt,A0A550KY48,GenBank,TGB21132,,,Y3X,ntrB,,,,,,PHI:123267,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,primates,9606,Homo sapiens (related: human),Ker-CT cell line,,,keratinocyte,"nitrate ABC transporter, permease protein",,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,35637237,PubMed,10.1038/s41598-022-12650-2,Sci Rep. 2022 May 30;12(1):9027,bob@hancocklab.com,Coinfected with S. aureus USA300 LAC,M A Alford 2022,2022,2 genes,Alford-2022-Competition between Pseudomonas ae,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20452,PHI:123267,UniProt,A6VDP3,GenBank,ABR83279,,,PA7,ntrC,,,,,,PHI:123266,287,Pseudomonas aeruginosa,557722,LESB58,opportunistic infection,primates,9606,Homo sapiens (related: human),Ker-CT cell line,,,keratinocyte,DNA-binding transcriptional regulator NtrC,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,35637237,PubMed,10.1038/s41598-022-12650-2,Sci Rep. 2022 May 30;12(1):9027,bob@hancocklab.com,Coinfected with S. aureus USA300 LAC,M A Alford 2022,2022,2 genes,Alford-2022-Competition between Pseudomonas ae,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20453,PHI:123268,UniProt,Q59L12,GenBank,AAO72959,,,SC5314,als3,chromosome R,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,agglutinin-like protein 3,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20454,PHI:123268,UniProt,Q59L12,GenBank,AAO72959,,,SC5314,als3,chromosome R,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,agglutinin-like protein 3,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,coinfection with P. mirabilis HI4320,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20455,PHI:123269,UniProt,Q59P39,GenBank,AOW27642,,,SC5314,efg1,chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,transcriptional regulator EFH1,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20456,PHI:123269,UniProt,Q59P39,GenBank,AOW27642,,,SC5314,efg1,chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,transcriptional regulator EFH1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,coinfection with P. mirabilis HI4320,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20457,PHI:123270,UniProt,G1UB67,GenBank,AOW31643,,,SC5314,eed1,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,transcriptional regulator DEF1,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20458,PHI:123270,UniProt,G1UB67,GenBank,AOW31643,,,SC5314,eed1,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,transcriptional regulator DEF1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,coinfection with P. mirabilis HI4320,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20459,PHI:123271,UniProt,Q5AJU7,GenBank,AOW28259,,,SC5314,cap1,chromosome 3,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,AP-1-like transcription factor CAP1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20460,PHI:123271,UniProt,Q5AJU7,GenBank,AOW28259,,,SC5314,cap1,chromosome 3,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,AP-1-like transcription factor CAP1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,coinfection with P. mirabilis HI4320,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20461,PHI:123272,UniProt,Q5ABE2,GenBank,AOW25775,,,SC5314,hgc1,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,hypha-specific G1 cyclin-related protein 1,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20462,PHI:123272,UniProt,Q5ABE2,GenBank,AOW25775,,,SC5314,hgc1,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,hypha-specific G1 cyclin-related protein 1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,coinfection with P. mirabilis HI4320,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20463,PHI:123269,UniProt,Q59P39,GenBank,AOW27642,,,SC5314,efg1,chromosome 2,,,,,PHI:123273,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,transcriptional regulator EFH1,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20464,PHI:123273,UniProt,P43079,GenBank,AAA59355,,,SC5314,cph1,,,,,,PHI:123269,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,transcription factor CPH1,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20465,PHI:123269,UniProt,Q59P39,GenBank,AOW27642,,,SC5314,efg1,chromosome 2,,,,,PHI:123273,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,transcriptional regulator EFH1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,coinfection with P. mirabilis HI4320,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20466,PHI:123273,UniProt,P43079,GenBank,AAA59355,,,SC5314,cph1,,,,,,PHI:123269,5476,Candida albicans,237561,SC5314,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,transcription factor CPH1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,coinfection with P. mirabilis HI4320,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20467,PHI:123274,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,extent of cell elongation protein 1,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20468,PHI:123274,UniProt,Q07730,GenBank,AAA34338,,,SC5314,ece1,,,,,,,5476,Candida albicans,,BWP17+cIP30,disseminated candidiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,extent of cell elongation protein 1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,coinfection with P. mirabilis HI4320,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20469,PHI:123275,UniProt,A0A7U1CQE7,GenBank,QKV33237,,,HN2p,hmpA,chromosome HN2p,,,,,,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,flavohemoprotein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection and coinfection with Candida albicans SC5314,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20470,PHI:123275,UniProt,A0A7U1CQE7,GenBank,QKV33237,,,HN2p,hmpA,chromosome HN2p,,,,,,584,Proteus mirabilis,,BA6163,urinary tract infection; urolithiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,flavohemoprotein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection and coinfection with Candida albicans SC5314,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20471,PHI:123276,UniProt,B4EYL5,GenBank,CAR43401,,,HI4320,fliF,,,,,,,584,Proteus mirabilis,529507,HI4320,urinary tract infection; urolithiasis,primates,9606,Homo sapiens (related: human),C2BBe1 cell line; HT29-MTX-E12 cells,,,intestinal epithelial cell,flagellar M-ring protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion,,,NN,35651758,PubMed,10.3389/fcimb.2022.866416,Front Cell Infect Microbiol. 2022 May 16;12:866416,ilse.jacobsen@leibniz-hki.de,monoinfection and coinfection with Candida albicans SC5314,M J Niemiec 2022,2022,10 genes,Niemiec-2022-Augmented Enterocyte Damage Durin,BATCH_113B,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20472,PHI:123277,UniProt,G4N9Z0,GenBank,EHA50442,,,70-15,MoRCN1 (MGG_03218),chromosome 4,,,Calcineurin A,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,calcineurin regulator,,,,reduced virulence,,,yes,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35783935,PubMed,10.3389/fpls.2022.925645,Front Plant Sci. 2022 Jun 16;13:925645,chenxiaolin@mail.hzau.edu.cn,A severe reduction in virulence was observed in the Morcn1 deletion mutant-infected plants compared with those infected by the wild type,C Liu 2022,2022,1 gene,Liu-2022-A Calcineurin Regulator MoRCN1 Is Imp,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20473,PHI:123277,UniProt,G4N9Z0,GenBank,EHA50442,,,70-15,MoRCN1 (MGG_03218),chromosome 4,,,Calcineurin A,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,calcineurin regulator,,,,reduced virulence,,,yes,,,reduced,,reduced; aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35783935,PubMed,10.3389/fpls.2022.925645,Front Plant Sci. 2022 Jun 16;13:925645,chenxiaolin@mail.hzau.edu.cn,A severe reduction in virulence was observed in the Morcn1 deletion mutant-infected plants compared with those infected by the wild type,C Liu 2022,2022,1 gene,Liu-2022-A Calcineurin Regulator MoRCN1 Is Imp,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20474,PHI:123278,UniProt,G4MND6,GenBank,EHA57050,,,70-15,MoNap1 (MGG_06924),chromosome 1,,,Cyc1; Histone H2A; Histone H2B,no data found; UniProt: P0CT12; GenBank: EHA50014; UniProt: P0CT13; GenBank: EHA50013,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,calcineurin regulator,,,,reduced virulence,,,,,small and restricted lesions,reduced; aberrant,,reduced; aberrant,wild type,no,SDS; calcofluor white; benomyl; Congo red; bleomycin; hydroxyurea,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; benomyl: CHEBI:3015; congo red: CHEBI:34653; bleomycin: CHEBI:22907; hydroxyurea: CHEBI:44423,,,,,gene deletion: full; gene complementation,,,NN,35887015,PubMed,10.3390/ijms23147662,Int J Mol Sci. 2022 Jul 11;23(14):7662,jplu@zju.edu.cn,The Monap1 deletion mutant displayed reduced virulence on barley leaves and rice seedlings. MoNap1 interacted with histones H2A and H 2 B and the B-type cyclin (Cyc1).,Q Wang 2022,2022,1 gene,"Wang-2022-Nucleosome Assembly Protein 1, Nap1",BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20475,PHI:123278,UniProt,G4MND6,GenBank,EHA57050,,,70-15,MoNap1 (MGG_06924),chromosome 1,,,Cyc1; Histone H2A; Histone H2B,no data found; UniProt: P0CT12; GenBank: EHA50014; UniProt: P0CT13; GenBank: EHA50013,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,calcineurin regulator,,,,reduced virulence,,,,,small and restricted lesions,reduced; aberrant,,reduced; aberrant,wild type,no,SDS; calcofluor white; benomyl; Congo red; bleomycin; hydroxyurea,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; benomyl: CHEBI:3015; congo red: CHEBI:34653; bleomycin: CHEBI:22907; hydroxyurea: CHEBI:44423,,,,,gene deletion: full; gene complementation,,,NN,35887015,PubMed,10.3390/ijms23147662,Int J Mol Sci. 2022 Jul 11;23(14):7662,jplu@zju.edu.cn,The Monap1 deletion mutant displayed reduced virulence on barley leaves and rice seedlings. MoNap1 interacted with histones H2A and H 2 B and the B-type cyclin (Cyc1).,Q Wang 2022,2022,1 gene,"Wang-2022-Nucleosome Assembly Protein 1, Nap1",BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20476,PHI:123279,UniProt,H1VPS8,GenBank,OBR07199,,,IMI 349063,ChPhb1 (Ch063_12292),chromosome 6,,,ChPhb2; ChATG24,UniProt: H1VAN0; GenBank: OBR15921; no data found,,80884,Colletotrichum higginsianum,,IMI349061,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,prohibitin,,,,reduced virulence,,,,,few and small necrotic lesions,wild type,,wild type,wild type,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,NN,35835849,PubMed,10.1038/s42003-022-03666-5,Commun Biol. 2022 Jul 14;5(1):698,luzheng@mail.hzau.edu.cn,ChPhb1 interacts with the autophagy-related protein ChATG24 and ChPhb2 in mitochondria. No phenotypic changes were detected in the ΔChPhb1 deletion mutant. ΔChPhb1 deletion mutant showed reduced virulence.,Y Yan 2022,2022,3 genes,Yan-2022-Mitochondrial prohibitin complex regu,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20477,PHI:123280,UniProt,H1VAN0,GenBank,OBR15921,,,IMI 349063,ChPhb2 (Ch063_08657),chromosome 1,,,ChPhb1; ChATG24,UniProt: H1VPS8; GenBank: OBR07199; no data found,,80884,Colletotrichum higginsianum,,IMI349061,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,prohibitin,,,,reduced virulence,,,,,few and small necrotic lesions,reduced,,reduced,wild type,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,NN,35835849,PubMed,10.1038/s42003-022-03666-5,Commun Biol. 2022 Jul 14;5(1):698,luzheng@mail.hzau.edu.cn,ChPhb2 interacts with the autophagy-related protein ChATG24 and ChPhb1 in mitochondria. The ΔChPhb2 deletion mutant displayed significantly attenuated growth and showed obviously reduced conidiation. ΔChPhb2 deletion mutant showed reduced virulence.,Y Yan 2022,2022,3 genes,Yan-2022-Mitochondrial prohibitin complex regu,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20478,PHI:123279,UniProt,H1VPS8,GenBank,OBR07199,,,IMI 349063,ChPhb1 (Ch063_12292),chromosome 6,,,,,PHI:123280,80884,Colletotrichum higginsianum,,IMI349061,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,prohibitin,,,,reduced virulence,,,,,few and small necrotic lesions,reduced,,reduced,wild type,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,NN,35835849,PubMed,10.1038/s42003-022-03666-5,Commun Biol. 2022 Jul 14;5(1):698,luzheng@mail.hzau.edu.cn,The ΔChPhb1/ChPhb2 double deletion mutant displayed significantly attenuated growth and showed obviously reduced conidiation and reduced virulence.,Y Yan 2022,2022,3 genes,Yan-2022-Mitochondrial prohibitin complex regu,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20479,PHI:123280,UniProt,H1VAN0,GenBank,OBR15921,,,IMI 349063,ChPhb2 (Ch063_08657),chromosome 1,,,,,PHI:123279,80884,Colletotrichum higginsianum,,IMI349061,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,prohibitin,,,,reduced virulence,,,,,few and small necrotic lesions,reduced,,reduced,wild type,no,H2O2; menadione,H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,NN,35835849,PubMed,10.1038/s42003-022-03666-5,Commun Biol. 2022 Jul 14;5(1):698,luzheng@mail.hzau.edu.cn,The ΔChPhb1/ChPhb2 double deletion mutant displayed significantly attenuated growth and showed obviously reduced conidiation and reduced virulence.,Y Yan 2022,2022,3 genes,Yan-2022-Mitochondrial prohibitin complex regu,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20480,PHI:123281,,no data found,,,,,,ChATG24,,,,ChPhb1; ChPhb2,UniProt: H1VPS8; GenBank: OBR07199; UniProt: H1VAN0; GenBank: OBR15921,,80884,Colletotrichum higginsianum,,IMI349061,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,prohibitin,,,,reduced virulence,,,,,few and small necrotic lesions,reduced,,reduced,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35835849,PubMed,10.1038/s42003-022-03666-5,Commun Biol. 2022 Jul 14;5(1):698,luzheng@mail.hzau.edu.cn,ChATG24 interacts with the autophagy-related protein ChPhb1 and ChPhb2 in mitochondria. The ΔChATG24 deletion mutant displayed significantly attenuated growth and showed reduced conidiation. ΔChATG24 deletion mutant showed reduced virulence.,Y Yan 2022,2022,3 genes,Yan-2022-Mitochondrial prohibitin complex regu,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20481,PHI:123282,,no data found,,,,,,Sse,,,,,,,1314,Streptococcus pyogenes,,MGAS5005,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,skin,secreted esterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial,,,NN,35887300,PubMed,10.3390/ijms23147954,Int J Mol Sci. 2022 Jul 19;23(14):7954,zhuhui@ems.hrbmu.edu.cn,"Absence of Sse was related to weakened skin invasion in a murine infection model, and significantly reduced GAS epithelial adherence, invasion, and intracellular survival.",X Zhang 2022,2022,1 gene,Zhang-2022-Functional and Transcriptome Analys,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20482,PHI:123282,,no data found,,,,,,Sse,,,,,,,1314,Streptococcus pyogenes,,MGAS5005,infection,primates,9606,Homo sapiens (related: human),Detroit 562 cell line,,,Detroit-562 cell,secreted esterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: partial,,,NN,35887300,PubMed,10.3390/ijms23147954,Int J Mol Sci. 2022 Jul 19;23(14):7954,zhuhui@ems.hrbmu.edu.cn,The multiplication rates of the sse deletion mutant were all significantly lower than those of the WT strain in Detroit 562 cells.,X Zhang 2022,2022,1 gene,Zhang-2022-Functional and Transcriptome Analys,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20483,PHI:123283,UniProt,I1RI44,GenBank,CEF78277,,,PH-1,FgFly1 (FGSG_03467; XP_011322248.1),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet; coleoptile,fungalysin metallopeptidase (M36),,,,reduced virulence,,,,yes,,reduced,wild type,reduced,reduced; aberrant,no,CaCl2; CuSO4; Congo red; SDS; caffeine,CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; congo red: CHEBI:34653; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full; gene complementation,,,NN,35887481,PubMed,10.3390/jof8070726,J Fungi (Basel). 2022 Jul 12;8(7):726,qiangli@nwsuaf.edu.cn,"The FgFly1 deletion mutant did not affect the ability to produce DON toxin, although it inhibited spore germination during asexual reproduction and reduction in pathogenicity compared with wild-type. FgFly1 interacted with host calmodulin-binding transcription activator.",X Wang 2022,2022,1 gene,Wang-2022-Functional Characterization of the M,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20484,PHI:123283,UniProt,I1RI44,GenBank,CEF78277,,,PH-1,FgFly1 (FGSG_03467; XP_011322248.1),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,filament,fungalysin metallopeptidase (M36),,,,reduced virulence,,,,yes,small lesion,reduced,wild type,reduced,reduced; aberrant,no,CaCl2; CuSO4; Congo red; SDS; caffeine,CaCl2: CHEBI:3312; CuSO4: CHEBI:23414; congo red: CHEBI:34653; SDS: CHEBI:8984; caffeine: CHEBI:27732,,,,,gene deletion: full; gene complementation,,,NN,35887481,PubMed,10.3390/jof8070726,J Fungi (Basel). 2022 Jul 12;8(7):726,qiangli@nwsuaf.edu.cn,"The FgFly1 deletion mutant did not affect the ability to produce DON toxin, although it inhibited spore germination during asexual reproduction and reduction in pathogenicity compared with wild-type.",X Wang 2022,2022,1 gene,Wang-2022-Functional Characterization of the M,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20485,PHI:123284,UniProt,A7E8F4,GenBank,EDN96656,,,1980,SsAGM1 (SS1G_01582),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,N-acetylglucosamine-phosphate mutase,,,,loss of pathogenicity,,,,yes,,,,wild type,,no,SDS; calcofluor white; Congo red; NaCl; KCl; D-sorbitol;,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924,,,,,altered gene expression / gene regulation: silencing,,,NN,35814696,PubMed,10.3389/fmicb.2022.938784,Front Microbiol. 2022 Jun 23;13:938784,panhongyu@jlu.edu.cn,"The growth rate of hyphae in gene-silenced transformants was significantly lower than in WT, CK, or overexpression transformants. Gene-silenced transformants never formed sclerotia even if the culture time was prolonged. The gene-silenced transformants were unable to invade intact leaves.",J Zhang 2022,2022,1 gene,Zhang-2022-SsAGM1-Mediated Uridine Diphosphate,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20486,PHI:123284,UniProt,A7E8F4,GenBank,EDN96656,,,1980,SsAGM1 (SS1G_01582),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3847,Glycine max (related: soybean),cv. Williams 82,,,leaf,N-acetylglucosamine-phosphate mutase,,,,loss of pathogenicity,,,,yes,,,,wild type,,no,SDS; calcofluor white; Congo red; NaCl; KCl; D-sorbitol;,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924,,,,,altered gene expression / gene regulation: silencing,,,NN,35814696,PubMed,10.3389/fmicb.2022.938784,Front Microbiol. 2022 Jun 23;13:938784,panhongyu@jlu.edu.cn,"The growth rate of hyphae in gene-silenced transformants was significantly lower than in WT, CK, or overexpression transformants. Gene-silenced transformants never formed sclerotia even if the culture time was prolonged. The gene-silenced transformants were unable to invade intact leaves.",J Zhang 2022,2022,1 gene,Zhang-2022-SsAGM1-Mediated Uridine Diphosphate,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20487,PHI:123284,UniProt,A7E8F4,GenBank,EDN96656,,,1980,SsAGM1 (SS1G_01582),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,leaf,N-acetylglucosamine-phosphate mutase,,,,loss of pathogenicity,,,,yes,,,,wild type,,no,SDS; calcofluor white; Congo red; NaCl; KCl; D-sorbitol;,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924,,,,,altered gene expression / gene regulation: silencing,,,NN,35814696,PubMed,10.3389/fmicb.2022.938784,Front Microbiol. 2022 Jun 23;13:938784,panhongyu@jlu.edu.cn,"The growth rate of hyphae in gene-silenced transformants was significantly lower than in WT, CK, or overexpression transformants. Gene-silenced transformants never formed sclerotia even if the culture time was prolonged. The gene-silenced transformants were unable to invade intact leaves.",J Zhang 2022,2022,1 gene,Zhang-2022-SsAGM1-Mediated Uridine Diphosphate,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20488,PHI:123284,UniProt,A7E8F4,GenBank,EDN96656,,,1980,SsAGM1 (SS1G_01582),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,N-acetylglucosamine-phosphate mutase,,,,unaffected pathogenicity,,,,yes,,,,wild type,,no,SDS; calcofluor white; Congo red; NaCl; KCl; D-sorbitol;,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924,,,,,altered gene expression / gene regulation: overexpression,,,NN,35814696,PubMed,10.3389/fmicb.2022.938784,Front Microbiol. 2022 Jun 23;13:938784,panhongyu@jlu.edu.cn,The lesion area indicated that the pathogenicity of gene overexpression transformants were not significantly different from WT.,J Zhang 2022,2022,1 gene,Zhang-2022-SsAGM1-Mediated Uridine Diphosphate,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20489,PHI:123284,UniProt,A7E8F4,GenBank,EDN96656,,,1980,SsAGM1 (SS1G_01582),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3847,Glycine max (related: soybean),cv. Williams 82,,,leaf,N-acetylglucosamine-phosphate mutase,,,,unaffected pathogenicity,,,,yes,,,,wild type,,no,SDS; calcofluor white; Congo red; NaCl; KCl; D-sorbitol;,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924,,,,,altered gene expression / gene regulation: overexpression,,,NN,35814696,PubMed,10.3389/fmicb.2022.938784,Front Microbiol. 2022 Jun 23;13:938784,panhongyu@jlu.edu.cn,The lesion area indicated that the pathogenicity of gene overexpression transformants were not significantly different from WT.,J Zhang 2022,2022,1 gene,Zhang-2022-SsAGM1-Mediated Uridine Diphosphate,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20490,PHI:123284,UniProt,A7E8F4,GenBank,EDN96656,,,1980,SsAGM1 (SS1G_01582),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,leaf,N-acetylglucosamine-phosphate mutase,,,,unaffected pathogenicity,,,,yes,,,,wild type,,no,SDS; calcofluor white; Congo red; NaCl; KCl; D-sorbitol;,SDS: CHEBI:8984; calcofluor white: CHEBI:50011; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924,,,,,altered gene expression / gene regulation: overexpression,,,NN,35814696,PubMed,10.3389/fmicb.2022.938784,Front Microbiol. 2022 Jun 23;13:938784,panhongyu@jlu.edu.cn,The lesion area indicated that the pathogenicity of gene overexpression transformants were not significantly different from WT.,J Zhang 2022,2022,1 gene,Zhang-2022-SsAGM1-Mediated Uridine Diphosphate,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20491,PHI:123285,,no data found,GenBank,SHI03762,,,OSU THCO2-90,hfpR (THC0290_1814),chromosome 1,,,,,,96345,Flavobacterium psychrophilum,,THCO2-90,bacterial cold-water disease,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,spleen,haem/haemoglobin receptor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35880611,PubMed,10.1080/21505594.2022.2101197,Virulence. 2022 Dec;13(1):1221-1241,tatiana.rochat@inrae.fr,Survival was significantly increased for fish infected with ΔhfpR. Colonization of spleen was significantly lower for groups infected with ΔhfpR.,Y Zhu 2022,2022,3 genes,Zhu-2022-Two functionally distinct heme_iron t,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20492,PHI:123286,UniProt,A6GX05,GenBank,SHI01659,,,OSU THCO2-90,bfpR (THC0290_1679),chromosome 1,,,,,,96345,Flavobacterium psychrophilum,,THCO2-90,bacterial cold-water disease,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,spleen,haem/haemoglobin receptor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35880611,PubMed,10.1080/21505594.2022.2101197,Virulence. 2022 Dec;13(1):1221-1241,tatiana.rochat@inrae.fr,The survival curves of fish inoculated with ΔbfpR or the wild-type were similar. No significant difference was observed between bacterial loads of fish infected with ΔbfpR or the wild-type.,Y Zhu 2022,2022,3 genes,Zhu-2022-Two functionally distinct heme_iron t,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20493,PHI:123287,,no data found,GenBank,SHI03750,,,OSU THCO2-90,hfpY (THC0290_1813),chromosome 1,,,,,,96345,Flavobacterium psychrophilum,,THCO2-90,bacterial cold-water disease,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,spleen,haem/haemoglobin receptor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35880611,PubMed,10.1080/21505594.2022.2101197,Virulence. 2022 Dec;13(1):1221-1241,tatiana.rochat@inrae.fr,Survival was significantly increased for fish infected with ΔhfpY. Colonization of spleen was significantly lower for groups infected with ΔhfpY.,Y Zhu 2022,2022,3 genes,Zhu-2022-Two functionally distinct heme_iron t,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20494,PHI:123285,,no data found,GenBank,SHI03762,,,OSU THCO2-90,hfpR (THC0290_1814),chromosome 1,,,,,PHI:123286,96345,Flavobacterium psychrophilum,,THCO2-90,bacterial cold-water disease,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,spleen,haem/haemoglobin receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35880611,PubMed,10.1080/21505594.2022.2101197,Virulence. 2022 Dec;13(1):1221-1241,tatiana.rochat@inrae.fr,Survival was significantly increased for fish infected with ΔhfpR/bfpR double mutant. Colonization of spleen was significantly lower for groups infected with ΔhfpR/bfpR double mutant.,Y Zhu 2022,2022,3 genes,Zhu-2022-Two functionally distinct heme_iron t,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20495,PHI:123286,UniProt,A6GX05,GenBank,SHI01659,,,OSU THCO2-90,bfpR (THC0290_1679),chromosome 1,,,,,PHI:123285,96345,Flavobacterium psychrophilum,,THCO2-90,bacterial cold-water disease,bony fishes,8022,Oncorhynchus mykiss (related: rainbow trout),,,,spleen,haem/haemoglobin receptor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35880611,PubMed,10.1080/21505594.2022.2101197,Virulence. 2022 Dec;13(1):1221-1241,tatiana.rochat@inrae.fr,Survival was significantly increased for fish infected with ΔhfpR/bfpR double mutant. Colonization of spleen was significantly lower for groups infected with ΔhfpR/bfpR double mutant.,Y Zhu 2022,2022,3 genes,Zhu-2022-Two functionally distinct heme_iron t,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20496,PHI:123288,,no data found,,,,,,rbpA,,,,,,,1307,Streptococcus suis,,ZY05719,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; liver; lung,RNA-binding protein A,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35903019,PubMed,10.1080/21505594.2022.2103233,Virulence. 2022 Dec;13(1):1304-1314,yaohch@njau.edu.cn,Mice infected with the ΔrbpA strain showed a significantly higher survival rate and less severe clinical signs than those challenged with the WT and complementary strains.,X Zhong 2022,2022,1 gene,Zhong-2022-Identification of the RNA-binding d,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20497,PHI:123288,,no data found,,,,,,rbpA,,,,,,,1307,Streptococcus suis,,ZY05719,streptococcal toxic shock syndrome,primates,9606,Homo sapiens (related: human),HEp-2 cell line,,,epithelial cell,RNA-binding protein A,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35903019,PubMed,10.1080/21505594.2022.2103233,Virulence. 2022 Dec;13(1):1304-1314,yaohch@njau.edu.cn,The adhesion of the ΔrbpA strain to HEp-2 cells was significantly decreased compared to that of the WT and complementary strains,X Zhong 2022,2022,1 gene,Zhong-2022-Identification of the RNA-binding d,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20498,PHI:123289,UniProt,A4QXV8,GenBank,EHA49567,,,70-15,MoADE12 (MGG_17000),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,adenylosuccinate synthetase,,,,reduced virulence,,,,yes,small lesions,reduced,reduced,wild type,wild type,no,H2O2; NaCl; rose bengal; Congo red; calcofluor white; sorbitol,H2O2: CHEBI:16240; NaCl: CHEBI:26710; rose bengal: CHEBI:52261; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,35893147,PubMed,10.3390/jof8080780,J Fungi (Basel). 2022 Jul 26;8(8):780,wangjy@zaas.ac.cn,The moade12 deletion mutant caused few small lesions on rice leaves compared to wild-type.,Z Zhang 2022,2022,1 gene,Zhang-2022-Adenylsuccinate Synthetase MoADE12,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20499,PHI:123290,UniProt,L2FK23,GenBank,KAF4475149,,,Nara gc5,CgFim1,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,fimbrin,,,,reduced virulence,,yes,,yes,small lesions,reduced; defective,,reduced; defective,reduced,no,H2O2; NaCl; Congo red; sorbitol; fludioxonil; iprodione; triadimefon; tebuconazole,H2O2: CHEBI:16240; NaCl: CHEBI:26710; Congo red: CHEBI:34653; sorbitol: CHEBI:30911; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909; triadimefon: CHEBI:9665; tebuconazole: CHEBI:81781,,,,,gene deletion: full; gene complementation,,,NN,35791045,PubMed,10.1111/mpp.13242,Mol Plant Pathol. 2022 Jul 5,wangqiannan@hainanu.edu.cn,"The knockout of CgFim1 led to impairment in vegetative growth, conidiation, and pathogenicity.",Y Zhang 2022,2022,1 gene,Zhang-2022-Actin-bundling protein fimbrin regu,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20500,PHI:123291,,no data found,GenBank,MAMH01000468,,,Fon019,FoIme2 (MAMH01000468),,ΔFoIme2-2 and ΔFoIme2-19,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Zaojia 8424,,,seedling,F-box protein required for pathogenicity,,,,reduced virulence,,,,,,reduced,,reduced,,no,SDS; Congo red; NaCl; KCl; H2O2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35788908,PubMed,10.1007/s00203-022-02964-0,Arch Microbiol. 2022 Jul 5;204(8):455,ermingliu@163.com,"The FoIme2-deleted mutants exhibited obvious morphological abnormalities, including slower vegetative growth, more branches in the edge hyphae and a reduction in conidia production. The deletion of FoIme2 also caused a reduction in pathogenicity.",J Xiao 2022,2022,1 gene,Xiao-2022-Protein kinase Ime2 is associated wi,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20501,PHI:123292,UniProt,A0A177DD11,GenBank,RYN77940,,,FERA 1177,AaAtg8,,,,,,,5599,Alternaria alternata,,,infection,eudicots,164113,Citrus x microcarpa (related: calamondin),,,,leaf,ubiquitin E3 ligase,,,,reduced virulence,,,,yes,,reduced; defective,,reduced,reduced,no,H2O2; cumyl-H2O2; tert-butyl-hydroxyperoxide; diethyl malonate,H2O2: CHEBI:16240; cumyl hydroperoxide: CHEBI:78673; tert-butyl-hydroxyperoxide: CAS:75-91-2; diethyl malonate: CHEBI:167785,,,,,gene deletion: full; gene complementation,,,NN,35810316,PubMed,10.1111/mpp.13247,Mol Plant Pathol. 2022 Jul 9,jane871057@gmail.com,Deleting AaAtg8 affected the development of conidia and appressorium-like structures. Pathogenicity tests assayed on detached citrus leaves revealed that deletion of AaAtg8 resulted in fungal strains with a severe reduction in virulence.,P-C Wu 2022,2022,1 gene,Wu-2022-Pexophagy is critical for fungal devel,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20502,PHI:123293,UniProt,G1XP67,GenBank,EGX45134,,,ATCC 24927,AoSlt2 (AOL_s00173g235),,,,AoSW16; AoCDC2,UniProt: G1XK81; GenBank: EGX46538; no data found,,2813651,Orbilia oligospora,756982,ATCC 24927,nematode trapping fungus,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,mitogen-activated protein (MAP) kinase,,,,loss of pathogenicity,,,,yes,,reduced,,reduced; defective,,no,sodium dodecyl sulfate; Congo red; H2O2; menadione; NaCl; sorbitol,SDS: CHEBI:8984; Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35829807,PubMed,10.1007/s11427-022-2118-0,Sci China Life Sci. 2022 Jul 8,jinkui960@ynu.edu.cn,Disruption of AoSlt2 led to loss of pathogenicity as shown by lack of trap formation in nematodes. AoSlt2 interacted with AoSW16 and AoCDC2.,M Xie 2022,2022,3 genes,Xie-2022-PKC-SWI6 signaling regulates asexual,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20503,PHI:123294,UniProt,G1XK81,GenBank,EGX46538,,,ATCC 24927,AoSW16 (AOL_s00109g110),,,,AoPKC; AoSLT2,UniProt: G1WZF5; GenBank: EGX53678; UniProt: G1XP67; GenBank: EGX45134,,2813651,Orbilia oligospora,756982,ATCC 24927,nematode trapping fungus,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,fungal transcription factor,,,,reduced virulence,,,,yes,,reduced; defective,,reduced; defective,reduced,no,sodium dodecyl sulfate; Congo red; H2O2; menadione; NaCl; sorbitol,SDS: CHEBI:8984; Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35829807,PubMed,10.1007/s11427-022-2118-0,Sci China Life Sci. 2022 Jul 8,jinkui960@ynu.edu.cn,Disruption of AoSW16 led to reduced virulence as shown by lower trap formation in nematodes. AoSW16 interacted with AoPKC and AoSLT2.,M Xie 2022,2022,3 genes,Xie-2022-PKC-SWI6 signaling regulates asexual,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20504,PHI:123295,UniProt,G1WZF5,GenBank,EGX53678,,,ATCC 24927,AoPKC (AOL_s00006g6),,,,AoSW16; AoBCK1,UniProt: G1XK81; GenBank: EGX46538; UniProt: G1X6I1; GenBank: EGX51239,,2813651,Orbilia oligospora,756982,ATCC 24927,nematode trapping fungus,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,protein kinase C,,,,reduced virulence,,,,yes,,reduced; defective,,reduced; defective,reduced,no,sodium dodecyl sulfate; Congo red; H2O2; menadione; NaCl; sorbitol,SDS: CHEBI:8984; Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35829807,PubMed,10.1007/s11427-022-2118-0,Sci China Life Sci. 2022 Jul 8,jinkui960@ynu.edu.cn,Disruption of AoPKC led to reduced virulence as shown by lower trap formation in nematodes. AoPKC interacted with AoSW16 and AoBCK1.,M Xie 2022,2022,3 genes,Xie-2022-PKC-SWI6 signaling regulates asexual,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20505,PHI:123296,UniProt,A0A0M4AMY8,GenBank,ALB06114,,,03-8,VmEP1,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Gala 3,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,NN,35851537,PubMed,10.1111/mpp.13248,Mol Plant Pathol. 2022 Jul 18,huanglili@nwsuaf.edu.cn,V. mali effector protein EP1 suppressed the host immune responses by interfering with the MdKRBP4-mediated resistance to V. mali during the infection.,W Wang 2022,2022,1 gene,Wang-2022-Valsa mali secretes an effector prot,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20506,PHI:123296,UniProt,A0A0M4AMY8,GenBank,ALB06114,,,03-8,VmEP1,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Gala 3,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient overexpression,,,NN,35851537,PubMed,10.1111/mpp.13248,Mol Plant Pathol. 2022 Jul 18,huanglili@nwsuaf.edu.cn,V. mali effector protein EP1 suppressed the host immune responses by interfering with the MdKRBP4-mediated resistance to V. mali during the infection.,W Wang 2022,2022,1 gene,Wang-2022-Valsa mali secretes an effector prot,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20507,PHI:123296,UniProt,A0A0M4AMY8,GenBank,ALB06114,,,03-8,VmEP1,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,4100,Nicotiana benthamiana (no common name found),cv. Gala 3,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,NN,35851537,PubMed,10.1111/mpp.13248,Mol Plant Pathol. 2022 Jul 18,huanglili@nwsuaf.edu.cn,V. mali effector protein EP1 suppressed the host immune responses by interfering with the MdKRBP4-mediated resistance to V. mali during the infection.,W Wang 2022,2022,1 gene,Wang-2022-Valsa mali secretes an effector prot,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20508,PHI:123297,UniProt,Q6FJK7,GenBank,CAG62563,,,CBS 138,"DUR1,2",chromosome M,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bladder; kidney; spleen,urea amidolyase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35795910,PubMed,10.1080/21505594.2022.2095716,Virulence. 2022 Dec;13(1):1285-1303,Dominique.Sanglard@chuv.ch,"DUR1,2 deletion resulted in significantly reduced virulence in the UTI model.",S Schrevens 2022,2022,4 genes,Schrevens-2022-Using in vivo transcriptomics a,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20509,PHI:123298,UniProt,A0A0W0EMV0,GenBank,KTB01123,,,,GAP1,,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bladder; kidney; spleen,amino acid permease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35795910,PubMed,10.1080/21505594.2022.2095716,Virulence. 2022 Dec;13(1):1285-1303,Dominique.Sanglard@chuv.ch,"Deletion of GAP1 in C. glabrata resulted in impaired growth on NS medium supplemented with either L-citrulline or L-tryptophan as the sole nitrogen source. GAP1 deletion resulted in a strong decrease in colonization of the bladder and kidneys in the UTI model, without abolishing spleen colonization.",S Schrevens 2022,2022,4 genes,Schrevens-2022-Using in vivo transcriptomics a,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20510,PHI:123299,UniProt,Q6FLE7,GenBank,CAG61917,,,CBS 138,MLS1,chromosome L,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bladder; kidney; spleen,malate synthase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35795910,PubMed,10.1080/21505594.2022.2095716,Virulence. 2022 Dec;13(1):1285-1303,Dominique.Sanglard@chuv.ch,"Deletion of MLS1 in C. glabrata resulted in abolishment of growth on minimal medium with either acetate or ethanol as a carbon source. The deletion strain was significantly impaired in colonization of the bladder and the kidney, while spleen colonization was not affected",S Schrevens 2022,2022,4 genes,Schrevens-2022-Using in vivo transcriptomics a,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20511,PHI:123300,UniProt,A0A0W0E2C6,GenBank,KTB01344,,,,VMA22,,,,,,,5476,Candida albicans,,,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bladder; kidney; spleen,vacuolar ATPase assembly protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35795910,PubMed,10.1080/21505594.2022.2095716,Virulence. 2022 Dec;13(1):1285-1303,Dominique.Sanglard@chuv.ch,Deletion of VMA22 in C. glabrata caused a significant decrease in colonization of the bladder.,S Schrevens 2022,2022,4 genes,Schrevens-2022-Using in vivo transcriptomics a,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20512,PHI:123301,UniProt,Q5ADR3,GenBank,AOW28725,,,SC5314,drs2,chromosome 3,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,THP-1 cell,aminophospholipid translocase,,,,reduced virulence,,,,yes,,,,,,no,,,,,,,gene deletion: full,,,NN,35788922,PubMed,10.1007/s10123-022-00262-9,Int Microbiol. 2022 Jul 5,drzeeshanfatima@gmail.com,Phagocytosis was enhanced in Δdrs2 mutant through macrophage killing assay indicating reduced virulence. Proinflammatory cytokine IL6 was enhanced and anti-infammatory cytokine IL-10 levels were decreased.,S Singh 2022,2022,1 gene,Singh-2022-Unique roles of aminophospholipid t,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20513,PHI:123302,UniProt,Q4WP41,GenBank,EAL89993,,,Af293,Nmo2,chromosome 4,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,nitronate monooxygenases,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; menadione; tert-butyl hydroperoxide; diamide,H2O2: CHEBI:16240; menadione: CHEBI:28869; tert-butyl hydroperoxide: CHEBI:64090; diamide: CHEBI:48958,,,,,gene deletion: full,,,NN,35887491,PubMed,10.3390/jof8070736,J Fungi (Basel). 2022 Jul 16;8(7):736,shekhova.elena@yandex.com,nmo2 knock-out strains were less virulent than the wild-type.,P T Nguyen 2022,2022,2 genes,Nguyen-2022-Understanding the Role of Nitronat,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20514,PHI:123303,UniProt,Q4X1I5,GenBank,EAL93280,,,Af293,Nmo5,chromosome 2,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,nitronate monooxygenases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35887491,PubMed,10.3390/jof8070736,J Fungi (Basel). 2022 Jul 16;8(7):736,shekhova.elena@yandex.com,nmo5 knock-out strains were less virulent than the wild-type.,P T Nguyen 2022,2022,2 genes,Nguyen-2022-Understanding the Role of Nitronat,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20515,PHI:123303,UniProt,G2XEK6,GenBank,EGY18257,,,VdLs.17,Vdchs1 (VDAG_08591),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,chitin synthase,,,,reduced virulence,,,yes,,,reduced,,wild type; aberrant,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,The conidiation in the Vdchs1 mutant was significantly impaired. The in vitro and in vivo penetration of Vdchs1 mutant was impaired. Vdchs1 deletion mutant exhibited reduced pathogenicity.,J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20516,PHI:123303,UniProt,G2XEK6,GenBank,EGY18257,,,VdLs.17,Vdchs1 (VDAG_08591),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,seedling,chitin synthase,,,,reduced virulence,,,yes,,,reduced,,wild type; aberrant,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,The conidiation in the Vdchs1 mutant was significantly impaired. The in vitro and in vivo penetration of Vdchs1 mutant was impaired. Vdchs1 deletion mutant exhibited reduced pathogenicity.,J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20517,PHI:123304,UniProt,G2XJ47,GenBank,EGY20550,,,VdLs.17,Vdchs2 (VDAG_10179),chromosome unknown,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,chitin synthase,,,,reduced virulence,,,no,yes,,reduced,,wild type,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,"Vdchs2 mutant exhibited an intact penetration ability, the reduced pathogenicity of the mutant strain could be attributed to a post-penetration virulence.",J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20518,PHI:123304,UniProt,G2XJ47,GenBank,EGY20550,,,VdLs.17,Vdchs2 (VDAG_10179),chromosome unknown,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,seedling,chitin synthase,,,,reduced virulence,,,no,yes,,reduced,,wild type,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,"Vdchs2 mutant exhibited an intact penetration ability, the reduced pathogenicity of the mutant strain could be attributed to a post-penetration virulence.",J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20519,PHI:123305,UniProt,G2WY98,GenBank,EGY21056,,,VdLs.17,Vdchs3 (VDAG_02580),chromosome 3,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,chitin synthase,,,,unaffected pathogenicity,,,no,,,reduced,,wild type; aberrant,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,Vdchs3 deletion mutant did not show reduced pathogenicity.,J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20520,PHI:123305,UniProt,G2WY98,GenBank,EGY21056,,,VdLs.17,Vdchs3 (VDAG_02580),chromosome 3,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,seedling,chitin synthase,,,,unaffected pathogenicity,,,no,,,reduced,,wild type; aberrant,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,Vdchs3 deletion mutant did not show reduced pathogenicity.,J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20521,PHI:123306,UniProt,G2WYP9,GenBank,EGY21701,,,VdLs.17,Vdchs4 (VDAG_03141),chromosome 6,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,chitin synthase,,,,reduced virulence,,,yes,,,reduced,,wild type,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,The conidiation in the Vdchs4 mutant was significantly impaired. The in vitro and in vivo penetration of Vdchs4 mutant was impaired. Vdchs4 deletion mutant exhibited reduced pathogenicity.,J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20522,PHI:123306,UniProt,G2WYP9,GenBank,EGY21701,,,VdLs.17,Vdchs4 (VDAG_03141),chromosome 6,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,seedling,chitin synthase,,,,reduced virulence,,,yes,,,reduced,,wild type,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,The conidiation in the Vdchs4 mutant was significantly impaired. The in vitro and in vivo penetration of Vdchs4 mutant was impaired. Vdchs4 deletion mutant exhibited reduced pathogenicity.,J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20523,PHI:123307,UniProt,G2WS86,GenBank,EGY13737,,,VdLs.17,Vdchs5 (VDAG_00419),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,chitin synthase,,,,reduced virulence,,,no,yes,,wild type,,wild type,reduced,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,"Vdchs5 mutant exhibited an intact penetration ability, the reduced pathogenicity of the mutant strain could be attributed to a post-penetration virulence.",J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20524,PHI:123307,UniProt,G2WS86,GenBank,EGY13737,,,VdLs.17,Vdchs5 (VDAG_00419),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,seedling,chitin synthase,,,,reduced virulence,,,no,yes,,wild type,,wild type,reduced,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,"Vdchs5 mutant exhibited an intact penetration ability, the reduced pathogenicity of the mutant strain could be attributed to a post-penetration virulence.",J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20525,PHI:123308,UniProt,G2WS87,GenBank,EGY13738,,,VdLs.17,Vdchs6 (VDAG_00420),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,chitin synthase,,,,reduced virulence,,,yes,,,reduced,,wild type; aberrant,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,The in vitro and in vivo penetration of Vdchs6 mutant was impaired. Vdchs6 deletion mutant exhibited reduced pathogenicity.,J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20526,PHI:123308,UniProt,G2WS87,GenBank,EGY13738,,,VdLs.17,Vdchs6 (VDAG_00420),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,seedling,chitin synthase,,,,reduced virulence,,,yes,,,reduced,,wild type; aberrant,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,The in vitro and in vivo penetration of Vdchs6 mutant was impaired. Vdchs6 deletion mutant exhibited reduced pathogenicity.,J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20527,PHI:123309,UniProt,G2WS43,GenBank,EGY13694,,,VdLs.17,Vdchs7 (VDAG_00376),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,chitin synthase,,,,reduced virulence,,,yes,,,reduced,,wild type; aberrant,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,The in vitro and in vivo penetration of Vdchs7 mutant was impaired. Vdchs7 deletion mutant exhibited reduced pathogenicity.,J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20528,PHI:123309,UniProt,G2WS43,GenBank,EGY13694,,,VdLs.17,Vdchs7 (VDAG_00376),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,seedling,chitin synthase,,,,reduced virulence,,,yes,,,reduced,,wild type; aberrant,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,The in vitro and in vivo penetration of Vdchs7 mutant was impaired. Vdchs7 deletion mutant exhibited reduced pathogenicity.,J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20529,PHI:123310,UniProt,G2X5A0,GenBank,EGY14241,,,VdLs.17,Vdchs8 (VDAG_05405),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,chitin synthase,,,,reduced virulence,,,no,yes,,reduced,,wild type,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,"The conidiation in the Vdchs8 mutant was significantly impaired. Vdchs8 mutant exhibited an intact penetration ability, the reduced pathogenicity of the mutant strain could be attributed to a post-penetration virulence.",J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20530,PHI:123310,UniProt,G2X5A0,GenBank,EGY14241,,,VdLs.17,Vdchs8 (VDAG_05405),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,seedling,chitin synthase,,,,reduced virulence,,,no,yes,,reduced,,wild type,wild type,no,NaCl; SDS; Congo red; calcofluor white; sorbitol,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011; sorbitol: CHEBI:30911,,,,,gene deletion: full,,,NN,35887437,PubMed,10.3390/jof8070681,J Fungi (Basel). 2022 Jun 28;8(7):681,zhangjie@im.ac.cn,"The conidiation in the Vdchs8 mutant was significantly impaired. Vdchs8 mutant exhibited an intact penetration ability, the reduced pathogenicity of the mutant strain could be attributed to a post-penetration virulence.",J Quinn 2022,2022,8 genes,Qin-2022-Chitin Synthase Genes Are Differentia,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20531,PHI:123311,UniProt,A0A384JZW9,GenBank,ATZ56113,,,B05.10,BcMettl4,chromosome BCIN12,"catalytic motif ""DPPW"" was mutated to ""APPA""",,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,methyltransferases,,,,reduced virulence,,,,,,wild type,,wild type,,no,NaCl; SDS; Congo red; sorbitol; H2O2; glycerol; KCl,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; glycerol: CHEBI:17754; KCl: CHEBI:32588,,,,,gene disruption; gene complementation; gene mutation: characterised,,,NN,35847085,PubMed,10.3389/fmicb.2022.925868,Front Microbiol. 2022 Jun 30;13:925868,wliang1@qau.edu.cn,"Deletion of BcMettl4 reduced the pathogenicity of B.cinerea on tomato. Mutation of catalytic motif ""DPPW"" caused reduced virulence.",Z Miao 2022,2022,4 genes,Miao-2022-BcMettl4-Mediated DNA Adenine N(6)-M,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20532,PHI:123312,UniProt,A0A384J9K6,GenBank,ATZ47305,,,B05.10,BcDamt,chromosome BCIN02,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,protein-lysine N-methyltransferase,,,,reduced virulence,,,,,,wild type,,wild type,,no,NaCl; SDS; Congo red; sorbitol; H2O2; glycerol; KCl,NaCl: CHEBI:26710; SDS: CHEBI:8984; Congo red: CHEBI:34653; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; glycerol: CHEBI:17754; KCl: CHEBI:32588,,,,,gene disruption; gene complementation; gene mutation: characterised,,,NN,35847085,PubMed,10.3389/fmicb.2022.925868,Front Microbiol. 2022 Jun 30;13:925868,wliang1@qau.edu.cn,Deletion of BcDamt reduced the pathogenicity of B.cinerea on tomato.,Z Miao 2022,2022,4 genes,Miao-2022-BcMettl4-Mediated DNA Adenine N(6)-M,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20533,PHI:123313,,no data found,GenBank,XP_001550664,,,B05.10,BcMSF2,chromosome 5,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,methyltransferases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35847085,PubMed,10.3389/fmicb.2022.925868,Front Microbiol. 2022 Jun 30;13:925868,wliang1@qau.edu.cn,The results showed that deletion of BcMFS2 did not reduce the virulence of B. cinerea,Z Miao 2022,2022,4 genes,Miao-2022-BcMettl4-Mediated DNA Adenine N(6)-M,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20534,PHI:123314,,no data found,GenBank,XP_024546624,,,B05.10,BcFDH,chromosome 1,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,methyltransferases,,,,reduced virulence,,,,,,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35847085,PubMed,10.3389/fmicb.2022.925868,Front Microbiol. 2022 Jun 30;13:925868,wliang1@qau.edu.cn,Deletion of the BcFDH gene reduced the pathogenicity of B. cinerea by 20%.,Z Miao 2022,2022,4 genes,Miao-2022-BcMettl4-Mediated DNA Adenine N(6)-M,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20535,PHI:123315,UniProt,Q0P7J0,GenBank,CAJ76300,,,IHE3034,ClbA,,,,,,,562,Escherichia coli,,APEC O2:K1:H7 strain M78,avian colibacillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,brain; lung; spleen,4'-phosphopantetheinyl transferase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35900973,PubMed,10.1371/journal.pone.0269102,PLoS One. 2022 Jul 28;17(7):e0269102,mengxia_1@126.com,Deletion of clbA decreased the virulence of APEC XM in mice.,X Meng 2022,2022,1 gene,Meng-2022-Phosphopantetheinyl transferase ClbA,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20536,PHI:123316,UniProt,A0A1P8YXK1,GenBank,AQA29228,,,0WU,Ecp20-2,,,,,,,5499,Fulvia fulva,,race 0,leaf mold (tomato),eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker Cf-0,,,leaf,effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation; other evidence: ectopic transformant,,,NN,35865936,PubMed,10.3389/fmicb.2022.919809,Front Microbiol. 2022 Jul 5;13:919809,mkjashni@modares.ac.ir,"Virulence assays confirmed a significant reduction of fungal biomass in plants inoculated with ecp20-2 deletion mutants compared to those inoculated with wild-type, ecp20-2-complemented mutants, and ectopic transformants.",M Karimi-Jashni 2022,2022,1 gene,Karimi-Jashni-2022-An Integrated Omics Approac,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20537,PHI:123317,UniProt,A0A0D1DWU6,GenBank,KIS68689,,,521,Mes1 (UMAG_03261),chromosome 8,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,,signal peptide peptidase,,,,loss of pathogenicity,yes,,,,,,,reduced; defective,,no,caffeine; calcofluor white; nikkomycin Z; sodium dodecyl sulfate (SDS); chlorpromazine,caffeine: CHEBI:27732; calcofluor white: CHEBI:50011; nikkomycin Z: CHEBI:623918; SDS: CHEBI:8984; chlorpromazine: CHEBI:3647,,,,,gene deletion: full,,,NN,35893127,PubMed,10.3390/jof8080759,J Fungi (Basel). 2022 Jul 22;8(8):759,davidc@us.es,"Infection with the wild-type strains led to tumour production in over 90% of the inoculated plants. By contrast, when plants were inoculated with the mutant strains, no symptoms of infection were observed, suggesting that Mes1 is necessary for virulence.",D Cánovas 2022,2022,1 gene,Cánovas-2022-The Fungal Protein Mes1 Is Requir,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20538,PHI:123318,UniProt,Q87VY7,GenBank,AAO58227,,,DC3000,thiD (pspto_4798),,,,,,PHI:123319; PHI:123320; PHI:123321,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Big Daddy Hybrid,,,leaf,"phosphomethylpyrimidine kinase, putative",,,thiamine biosynthetic pathway,reduced virulence,,,,,,,,wild type; reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35783427,PubMed,10.3389/fmicb.2022.903258,Front Microbiol. 2022 Jun 17;13:903258,wangh@hbaas.com,"TBS pathwayand ApbE play an important role in growth, colonization, and disease development in PstDC3000",J Liu 2022,2022,5 genes,Liu-2022-Thiamine Is Required for Virulence an,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20539,PHI:123319,UniProt,Q87VY6,GenBank,AAO58228,,,DC3000,thiE (pspto_4799),,,,,,PHI:123318; PHI:123320; PHI:123321,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Big Daddy Hybrid,,,leaf,thiamine-phosphate synthase,,,thiamine biosynthetic pathway,reduced virulence,,,,,,,,wild type; reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35783427,PubMed,10.3389/fmicb.2022.903258,Front Microbiol. 2022 Jun 17;13:903258,wangh@hbaas.com,"TBS pathwayand ApbE play an important role in growth, colonization, and disease development in PstDC3000",J Liu 2022,2022,5 genes,Liu-2022-Thiamine Is Required for Virulence an,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20540,PHI:123320,UniProt,Q88AF7,GenBank,AAO53977,,,DC3000,thiS (pspto_0433),,,,,,PHI:123318; PHI:123319; PHI:123321,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Big Daddy Hybrid,,,leaf,thiamine biosynthesis protein ThiS,,,thiamine biosynthetic pathway,reduced virulence,,,,,,,,wild type; reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35783427,PubMed,10.3389/fmicb.2022.903258,Front Microbiol. 2022 Jun 17;13:903258,wangh@hbaas.com,"TBS pathwayand ApbE play an important role in growth, colonization, and disease development in PstDC3000",J Liu 2022,2022,5 genes,Liu-2022-Thiamine Is Required for Virulence an,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20541,PHI:123321,UniProt,Q88AF6,GenBank,AAO53978,,,DC3000,thiG (pspto_0434),,,,,,PHI:123318; PHI:123319; PHI:123320,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Big Daddy Hybrid,,,leaf,thiazole synthase,,,thiamine biosynthetic pathway,reduced virulence,,,,,,,,wild type; reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35783427,PubMed,10.3389/fmicb.2022.903258,Front Microbiol. 2022 Jun 17;13:903258,wangh@hbaas.com,"TBS pathwayand ApbE play an important role in growth, colonization, and disease development in PstDC3000",J Liu 2022,2022,5 genes,Liu-2022-Thiamine Is Required for Virulence an,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20542,PHI:123322,UniProt,Q884I7,GenBank,AAO55623,,,DC3000,apbE (pspto_2105),,,,,,,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Big Daddy Hybrid,,,leaf,FAD:protein FMN transferase,,,thiamine biosynthetic pathway,reduced virulence,,,,,,,,wild type,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35783427,PubMed,10.3389/fmicb.2022.903258,Front Microbiol. 2022 Jun 17;13:903258,wangh@hbaas.com,"TBS pathwayand ApbE play an important role in growth, colonization, and disease development in PstDC3000",J Liu 2022,2022,5 genes,Liu-2022-Thiamine Is Required for Virulence an,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20543,PHI:123318,UniProt,Q87VY7,GenBank,AAO58227,,,DC3000,thiD (pspto_4798),,,,,,PHI:123319,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Big Daddy Hybrid,,,leaf,"phosphomethylpyrimidine kinase, putative",,,thiamine biosynthetic pathway,reduced virulence,,,,,,,,wild type; reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35783427,PubMed,10.3389/fmicb.2022.903258,Front Microbiol. 2022 Jun 17;13:903258,wangh@hbaas.com,"TBS pathwayand ApbE play an important role in growth, colonization, and disease development in PstDC3000",J Liu 2022,2022,5 genes,Liu-2022-Thiamine Is Required for Virulence an,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20544,PHI:123319,UniProt,Q87VY6,GenBank,AAO58228,,,DC3000,thiE (pspto_4799),,,,,,PHI:123318,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Big Daddy Hybrid,,,leaf,thiamine-phosphate synthase,,,thiamine biosynthetic pathway,reduced virulence,,,,,,,,wild type; reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35783427,PubMed,10.3389/fmicb.2022.903258,Front Microbiol. 2022 Jun 17;13:903258,wangh@hbaas.com,"TBS pathwayand ApbE play an important role in growth, colonization, and disease development in PstDC3000",J Liu 2022,2022,5 genes,Liu-2022-Thiamine Is Required for Virulence an,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20545,PHI:123320,UniProt,Q88AF7,GenBank,AAO53977,,,DC3000,thiS (pspto_0433),,,,,,PHI:123321,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Big Daddy Hybrid,,,leaf,thiamine biosynthesis protein ThiS,,,thiamine biosynthetic pathway,reduced virulence,,,,,,,,wild type; reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35783427,PubMed,10.3389/fmicb.2022.903258,Front Microbiol. 2022 Jun 17;13:903258,wangh@hbaas.com,"TBS pathwayand ApbE play an important role in growth, colonization, and disease development in PstDC3000",J Liu 2022,2022,5 genes,Liu-2022-Thiamine Is Required for Virulence an,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20546,PHI:123321,UniProt,Q88AF6,GenBank,AAO53978,,,DC3000,thiG (pspto_0434),,,,,,PHI:123320,317,Pseudomonas syringae,223283,pv. tomato strain DC3000,bacterial speck,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Big Daddy Hybrid,,,leaf,thiazole synthase,,,thiamine biosynthetic pathway,reduced virulence,,,,,,,,wild type; reduced,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35783427,PubMed,10.3389/fmicb.2022.903258,Front Microbiol. 2022 Jun 17;13:903258,wangh@hbaas.com,"TBS pathwayand ApbE play an important role in growth, colonization, and disease development in PstDC3000",J Liu 2022,2022,5 genes,Liu-2022-Thiamine Is Required for Virulence an,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20547,PHI:123323,UniProt,S0DJE0,GenBank,CCT62381,,,IMI 58289,FfCOX17 (FFUJ_01072),,,,,,,5127,Fusarium fujikuroi,,,bakanae,monocots,4530,Oryza sativa (related: rice),cv. Ninggeng 7,,,seed,related to COX17 protein (cytochrome c oxidase copper chaperone),,,,unaffected pathogenicity,,,,,,reduced,,reduced,defective,no,NaCl; sorbitol; H2O2; Congo red; CuCl2; LiCl; CaCl2; MgCl2; ZnCl2; glucose; fludioxonil; prochloraz; fluazinam; phenamacril; SDS; KCl,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; H2O2: CHEBI:16240; Congo red: CHEBI:34653; CuCl2: CHEBI:49553; LiCl: CHEBI:48607; CaCl2: CHEBI:3312; MgCl2: CHEBI:6636; ZnCl2: CHEBI:49976; glucose: CHEBI:17234; fludioxonil: CHEBI:81763; prochloraz: CHEBI:8434; fluazinam: CHEBI:81843; phenamacril: CAS:3336-69-4; SDS: CHEBI:8984; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,35878165,PubMed,10.3390/toxins14070427,Toxins (Basel). 2022 Jun 22;14(7):427,2018202062@njau.edu.cn,"Ff-COX17 deletion mutants showed a decrease in vegetative growth and asexual reproduction, sensitivity to oxidative stress, osmotic stress, and increased sensitivity to cell wall stress, heat shock stress, and high concentration glucose. In addition, DFfCOX17 also showed increased sensitivity to fungicide fluazinam and fludioxonil and decreased sensitivity to phenamacril and prochloraz.",X Mao 2022,2022,1 gene,Mao-2022-FfCOX17 is Involved in Fumonisins Pro,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20548,PHI:123324,,no data found,,,,,,AaDot1 (AAL_g3463),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone methyltransferases,,,,unaffected pathogenicity,,,,,necrotic lesions,,wild type,wild type,,no,sorbitol; NaCl; KCl; H2O2; SDS; Congo red; CuSO4; CaCl2; hydroxyurea; camptothecin; chlorothalonil; mancozeb; boscalid,sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; CaCl2: CHEBI:3312; hydroxyurea: CHEBI:44423; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full,,,NN,35783406,PubMed,10.3389/fmicb.2022.924476,Front Microbiol. 2022 Jun 16;13:924476,xukai@zafu.edu.cn,"histone methylation is involved in the fungal growth, pathogenicity, conidiation, DNA damage repair, multiple stress response, and carbon source utilization of A. alternata.",S Meng 2022,2022,6 genes,Meng-2022-Histone Methylation Is Required for,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20549,PHI:123325,,no data found,,,,,,AaHMT1 (AAL_g2753),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone methyltransferases,,,,unaffected pathogenicity,,,,,necrotic lesions,,wild type,wild type,,no,sorbitol; NaCl; KCl; H2O2; SDS; Congo red; CuSO4; CaCl2; hydroxyurea; camptothecin; chlorothalonil; mancozeb; boscalid,sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; CaCl2: CHEBI:3312; hydroxyurea: CHEBI:44423; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full,,,NN,35783406,PubMed,10.3389/fmicb.2022.924476,Front Microbiol. 2022 Jun 16;13:924476,xukai@zafu.edu.cn,"histone methylation is involved in the fungal growth, pathogenicity, conidiation, DNA damage repair, multiple stress response, and carbon source utilization of A. alternata.",S Meng 2022,2022,6 genes,Meng-2022-Histone Methylation Is Required for,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20550,PHI:123326,,no data found,,,,,,AaHnrnp (AAL_g5237),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone methyltransferases,,,,reduced virulence,,,,,reduced necrotic lesions,,wild type,defective,,no,sorbitol; NaCl; KCl; H2O2; SDS; Congo red; CuSO4; CaCl2; hydroxyurea; camptothecin; chlorothalonil; mancozeb; boscalid,sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; CaCl2: CHEBI:3312; hydroxyurea: CHEBI:44423; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full,,,NN,35783406,PubMed,10.3389/fmicb.2022.924476,Front Microbiol. 2022 Jun 16;13:924476,xukai@zafu.edu.cn,"histone methylation is involved in the fungal growth, pathogenicity, conidiation, DNA damage repair, multiple stress response, and carbon source utilization of A. alternata.",S Meng 2022,2022,6 genes,Meng-2022-Histone Methylation Is Required for,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20551,PHI:123327,,no data found,,,,,,AaSet1 (AAL_g7533),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone methyltransferases,,,,reduced virulence,,,,,reduced necrotic lesions,,reduced,reduced; defective,,no,sorbitol; NaCl; KCl; H2O2; SDS; Congo red; CuSO4; CaCl2; hydroxyurea; camptothecin; chlorothalonil; mancozeb; boscalid,sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; CaCl2: CHEBI:3312; hydroxyurea: CHEBI:44423; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full,,,NN,35783406,PubMed,10.3389/fmicb.2022.924476,Front Microbiol. 2022 Jun 16;13:924476,xukai@zafu.edu.cn,"histone methylation is involved in the fungal growth, pathogenicity, conidiation, DNA damage repair, multiple stress response, and carbon source utilization of A. alternata.",S Meng 2022,2022,6 genes,Meng-2022-Histone Methylation Is Required for,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20552,PHI:123328,,no data found,,,,,,AaSet2 (AAL_g4603),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone methyltransferases,,,,reduced virulence,,,,,no visible lesions,,reduced,reduced; defective,,no,sorbitol; NaCl; KCl; H2O2; SDS; Congo red; CuSO4; CaCl2; hydroxyurea; camptothecin; chlorothalonil; mancozeb; boscalid,sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; CaCl2: CHEBI:3312; hydroxyurea: CHEBI:44423; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full,,,NN,35783406,PubMed,10.3389/fmicb.2022.924476,Front Microbiol. 2022 Jun 16;13:924476,xukai@zafu.edu.cn,"histone methylation is involved in the fungal growth, pathogenicity, conidiation, DNA damage repair, multiple stress response, and carbon source utilization of A. alternata.",S Meng 2022,2022,6 genes,Meng-2022-Histone Methylation Is Required for,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20553,PHI:123329,,no data found,,,,,,AaGhd2 (AAL_g2163),,,,,,,5599,Alternaria alternata,,Z7,brown spot,eudicots,85571,Citrus reticulata (related: tangerine),cv. Blanco,,,leaf,histone demethylases,,,,reduced virulence,,,,,reduced necrotic lesions,,wild type,wild type,,no,sorbitol; NaCl; KCl; H2O2; SDS; Congo red; CuSO4; CaCl2; hydroxyurea; camptothecin; chlorothalonil; mancozeb; boscalid,sorbitol: CHEBI:17924; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; SDS: CHEBI:8984; Congo red: CHEBI:34653; CuSO4: CHEBI:23414; CaCl2: CHEBI:3312; hydroxyurea: CHEBI:44423; camptothecin: CHEBI:27656; chlorothalonil: CHEBI:3639; mancozeb: CHEBI:52492; boscalid: CHEBI:81822,,,,,gene deletion: full,,,NN,35783406,PubMed,10.3389/fmicb.2022.924476,Front Microbiol. 2022 Jun 16;13:924476,xukai@zafu.edu.cn,"histone methylation is involved in the fungal growth, pathogenicity, conidiation, DNA damage repair, multiple stress response, and carbon source utilization of A. alternata.",S Meng 2022,2022,6 genes,Meng-2022-Histone Methylation Is Required for,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20554,PHI:123330,,no data found,,,,,,edcA,,,,,,PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123337; PHI:123338; PHI:123339; PHI:123340; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,diguanylate cyclase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20555,PHI:123331,,no data found,,,,,,edcB,,,,,,PHI:123330; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123337; PHI:123338; PHI:123339; PHI:123340; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,diguanylate cyclase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20556,PHI:123332,,no data found,,,,,,edcC,,,,,,PHI:123330; PHI:123331; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123337; PHI:123338; PHI:123339; PHI:123340; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,diguanylate cyclase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20557,PHI:123333,,no data found,,,,,,edcD,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123334; PHI:123335; PHI:123336; PHI:123337; PHI:123338; PHI:123339; PHI:123340; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,diguanylate cyclase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20558,PHI:123334,,no data found,,,,,,edcE,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123335; PHI:123336; PHI:123337; PHI:123338; PHI:123339; PHI:123340; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,diguanylate cyclase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20559,PHI:123335,UniProt,Q6CZA8,GenBank,CAG77142,,,SCRI1043,pdeA,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123337; PHI:123338; PHI:123339; PHI:123340; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20560,PHI:123336,,no data found,,,,,,pdeB,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123337; PHI:123338; PHI:123339; PHI:123340; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20561,PHI:123337,,no data found,,,,,,pdeC,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123338; PHI:123339; PHI:123340; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20562,PHI:123338,,no data found,GenBank,CBJ48052,,,ATCC 49946,EAM_3378,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123337; PHI:123339; PHI:123340; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,putative signaling protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20563,PHI:123339,,no data found,GenBank,CBJ47810,,,ATCC 49946,EAM_3136 (CsrD),,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123337; PHI:123338; PHI:123340; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,putative signal transduction protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20564,PHI:123340,,no data found,GenBank,CBJ47123,,,ATCC 49946,EAM_2449,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123337; PHI:123338; PHI:123339; PHI:123341,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,putative signal transduction protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20565,PHI:123341,,no data found,GenBank,CBJ46254,,,ATCC 49946,EAM_1579,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123337; PHI:123338; PHI:123339; PHI:123340,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,conserved hypothetical protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20566,PHI:123330,,no data found,,,,,,edcA,,,,,,PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123337,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20567,PHI:123331,,no data found,,,,,,edcB,,,,,,PHI:123330; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123337,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20568,PHI:123332,,no data found,,,,,,edcC,,,,,,PHI:123330; PHI:123331; PHI:123333; PHI:123334; PHI:123335; PHI:123336; PHI:123337,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20569,PHI:123333,,no data found,,,,,,edcD,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123334; PHI:123335; PHI:123336; PHI:123337,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20570,PHI:123334,,no data found,,,,,,edcE,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123335; PHI:123336; PHI:123337,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,diguanylate cyclase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20571,PHI:123335,UniProt,Q6CZA8,GenBank,CAG77142,,,SCRI1043,pdeA,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123336; PHI:123337,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20572,PHI:123336,,no data found,,,,,,pdeB,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123337,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20573,PHI:123337,,no data found,,,,,,pdeC,,,,,,PHI:123330; PHI:123331; PHI:123332; PHI:123333; PHI:123334; PHI:123335; PHI:123336,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,shoot,phosphodiesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35914003,PubMed,10.1371/journal.ppat.1010737,PLoS Pathog. 2022 Aug 1;18(8):e1010737,kharadir@msu.edu,"Biofilm formation was regulated by all 5 Dgcs, whereas type III secretion and disease development were differentially regulated by specific Dgcs",R R Kharadi 2022,2022,12 genes,Kharadi-2022-A complete twelve-gene deletion n,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20574,PHI:123342,,no data found,,,,,,CgnoxA,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,NADPH oxidases,,,,unaffected pathogenicity,,yes,no,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35782153,PubMed,10.3389/fcimb.2022.845133,Front Cell Infect Microbiol. 2022 Jun 15;12:845133,wangqiannan@hainanu.edu.cn,"CgNOXB and CgNOXR regulate the production and distribution of ROS in hyphal tips and appressoria, control the specialized remodeling of F-actin in hyphal tips and appressoria, and are involved in fungal cell wall biosynthesis",N Liu 2022,2022,3 genes,Liu-2022-NADPH Oxidases Play a Role in Pathoge,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20575,PHI:123343,,no data found,,,,,,CgnoxB,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,NADPH oxidases,,,,reduced virulence,,yes,yes,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35782153,PubMed,10.3389/fcimb.2022.845133,Front Cell Infect Microbiol. 2022 Jun 15;12:845133,wangqiannan@hainanu.edu.cn,"CgNOXB and CgNOXR regulate the production and distribution of ROS in hyphal tips and appressoria, control the specialized remodeling of F-actin in hyphal tips and appressoria, and are involved in fungal cell wall biosynthesis",N Liu 2022,2022,3 genes,Liu-2022-NADPH Oxidases Play a Role in Pathoge,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20576,PHI:123344,,no data found,,,,,,CgnoxR,,,,,,,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,NADPH oxidases,,,,reduced virulence,,yes,yes,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35782153,PubMed,10.3389/fcimb.2022.845133,Front Cell Infect Microbiol. 2022 Jun 15;12:845133,wangqiannan@hainanu.edu.cn,"CgNOXB and CgNOXR regulate the production and distribution of ROS in hyphal tips and appressoria, control the specialized remodeling of F-actin in hyphal tips and appressoria, and are involved in fungal cell wall biosynthesis",N Liu 2022,2022,3 genes,Liu-2022-NADPH Oxidases Play a Role in Pathoge,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20577,PHI:123342,,no data found,,,,,,CgnoxA,,,,,,PHI:123343,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,NADPH oxidases,,,,reduced virulence,,yes,yes,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35782153,PubMed,10.3389/fcimb.2022.845133,Front Cell Infect Microbiol. 2022 Jun 15;12:845133,wangqiannan@hainanu.edu.cn,"CgNOXB and CgNOXR regulate the production and distribution of ROS in hyphal tips and appressoria, control the specialized remodeling of F-actin in hyphal tips and appressoria, and are involved in fungal cell wall biosynthesis",N Liu 2022,2022,3 genes,Liu-2022-NADPH Oxidases Play a Role in Pathoge,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20578,PHI:123343,,no data found,,,,,,CgnoxB,,,,,,PHI:123342,474922,Colletotrichum gloeosporioides,,,anthracnose (ficus),eudicots,3981,Hevea brasiliensis (related: rubber tree),,,,leaf,NADPH oxidases,,,,reduced virulence,,yes,yes,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35782153,PubMed,10.3389/fcimb.2022.845133,Front Cell Infect Microbiol. 2022 Jun 15;12:845133,wangqiannan@hainanu.edu.cn,"CgNOXB and CgNOXR regulate the production and distribution of ROS in hyphal tips and appressoria, control the specialized remodeling of F-actin in hyphal tips and appressoria, and are involved in fungal cell wall biosynthesis",N Liu 2022,2022,3 genes,Liu-2022-NADPH Oxidases Play a Role in Pathoge,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20579,PHI:123345,UniProt,A0A380INX8,GenBank,SUN10472,,,NCTC6175,copY,,,,,,,1311,Streptococcus agalactiae,,874391,pneumonia; meningitis,primates,9606,Homo sapiens (related: human),U-937 cell line,,,macrophage,negative transcriptional regulator-copper transport operon,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation,,,NN,35862444,PubMed,10.1371/journal.ppat.1010607,PLoS Pathog. 2022 Jul 21;18(7):e1010607,matthew.sullivan@griffith.edu.au,cross-system complexity driven by CopY in bacteria regulate cellular management of metal stress and survival,M J Sullivan 2022,2022,2 genes,Sullivan-2022-Regulatory cross-talk supports r,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20580,PHI:123345,UniProt,A0A380INX8,GenBank,SUN10472,,,NCTC6175,copY,,,,,,,1311,Streptococcus agalactiae,,874391,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; brain; heart; lung; liver; spleen; kidney; bladder,negative transcriptional regulator-copper transport operon,,,,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene mutation,,,NN,35862444,PubMed,10.1371/journal.ppat.1010607,PLoS Pathog. 2022 Jul 21;18(7):e1010607,matthew.sullivan@griffith.edu.au,cross-system complexity driven by CopY in bacteria regulate cellular management of metal stress and survival,M J Sullivan 2022,2022,2 genes,Sullivan-2022-Regulatory cross-talk supports r,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20581,PHI:123346,UniProt,X5KI93,GenBank,AIK72111,,,GBS1-NY,covR,,,,,,,1311,Streptococcus agalactiae,,874391,pneumonia; meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,blood; brain; heart; lung; liver; spleen; kidney; bladder,DNA-binding response regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,NN,35862444,PubMed,10.1371/journal.ppat.1010607,PLoS Pathog. 2022 Jul 21;18(7):e1010607,matthew.sullivan@griffith.edu.au,cross-system complexity driven by CopY in bacteria regulate cellular management of metal stress and survival,M J Sullivan 2022,2022,2 genes,Sullivan-2022-Regulatory cross-talk supports r,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20582,PHI:123347,,no data found,,,,,,TcCAL1,,fused to a 6X histidine tag,,,,,5693,Trypanosoma cruzi,,,Chagas disease,primates,9534,Chlorocebus aethiops (related: grivet),Vero cell line,,,Vero cell,kinetoplastid-specific protein,,,,increased virulence (hypervirulence),,,yes,,,reduced,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,35846750,PubMed,10.3389/fcimb.2022.901880,Front Cell Infect Microbiol. 2022 Jun 30;12:901880,marian.potenza@gmail.com,significant decrease in metacyclogenesis percentages in TcCAL1-6xHis overexpressing parasites compared to control,J Rodríguez-Durán 2022,2022,1 gene,Rodríguez-Durán-2022-The Kinetoplastid-Specifi,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20583,PHI:123348,,no data found,,,,,,UvPr1a,,"Inhibitor I9 domain truncation, Peptidase S8 domain truncation",,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial,,,NN,35861434,PubMed,10.1093/plphys/kiac334,Plant Physiol. 2022 Jul 21;kiac334,luzheng@mail.hzau.edu.cn,"Inhibitor I9 domain did not inhibit Bax-induced PCD, whereas the Peptidase S8 domain could inhibit PCD, suggesting that Inhibitor I9 domain might not directly regulate Bax-related immune pathways.",X Chen 2022,2022,1 gene,Chen-2022-A secreted fungal subtilase interfer,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20584,PHI:123348,,no data found,,,,,,UvPr1a,,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,increased,,reduced,,no,,,,,,,gene deletion: full; gene complementation; heterologous expression; other evidence: transgenic plant,,,NN,35861434,PubMed,10.1093/plphys/kiac334,Plant Physiol. 2022 Jul 21;kiac334,luzheng@mail.hzau.edu.cn,"Complementation of ΔUvPr1a with Inhibitor I9 domain (UvPr1aI9)of UvPr1a revealed that it was essential for mycelial growth, conidiation, and virulence of U. virens. Heterologous expression of UvPr1a in rice (Oryza sativa) enhanced plant susceptibility to rice pathogens. UvPr1a interacted with the important rice protein SUPPRESSOR OF G2 ALLELE OF skp1 (OsSGT1), a positive regulator of innate immunity against multiple rice pathogens.",X Chen 2022,2022,1 gene,Chen-2022-A secreted fungal subtilase interfer,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20585,PHI:123349,,no data found,,,,,,AvrPm17,,,,,,,34373,Blumeria graminis,1689686,f. sp. triticale isolate THUN-12,powdery mildew,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression: overexpression,,,NN,35857869,PubMed,10.1073/pnas.2108808119,Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2108808119,marion.mueller@botinst.uzh.ch,Pm17 resistance gene introgressed from rye to wheat provided broad resistance against powdery mildew (Blumeria graminis),M C Müller 2022,2022,2 gene,Müller-2022-Ancient variation of the AvrPm17 g,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20586,PHI:123350,,no data found,,,,,,AvrPm17,,,,,,,34373,Blumeria graminis,62690,f. sp. tritici isolate Bgt_96224,powdery mildew,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression: overexpression,,,NN,35857869,PubMed,10.1073/pnas.2108808119,Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2108808119,marion.mueller@botinst.uzh.ch,Pm17 resistance gene introgressed from rye to wheat provided broad resistance against powdery mildew (Blumeria graminis),M C Müller 2022,2022,2 gene,Müller-2022-Ancient variation of the AvrPm17 g,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20587,PHI:123349,,no data found,,,,,,AvrPm17,,,,,,,34373,Blumeria graminis,1689686,f. sp. triticale isolate THUN-12,powdery mildew,monocots,4565,Triticum aestivum (related: bread wheat),cv. Amigo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression: overexpression,,,NN,35857869,PubMed,10.1073/pnas.2108808119,Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2108808119,marion.mueller@botinst.uzh.ch,Pm17 resistance gene introgressed from rye to wheat provided broad resistance against powdery mildew (Blumeria graminis),M C Müller 2022,2022,2 gene,Müller-2022-Ancient variation of the AvrPm17 g,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20588,PHI:123350,,no data found,,,,,,AvrPm17,,,,,,,34373,Blumeria graminis,62690,f. sp. tritici isolate Bgt_96224,powdery mildew,monocots,4565,Triticum aestivum (related: bread wheat),cv. Amigo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression: overexpression,,,NN,35857869,PubMed,10.1073/pnas.2108808119,Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2108808119,marion.mueller@botinst.uzh.ch,Pm17 resistance gene introgressed from rye to wheat provided broad resistance against powdery mildew (Blumeria graminis),M C Müller 2022,2022,2 gene,Müller-2022-Ancient variation of the AvrPm17 g,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20589,PHI:123351,,no data found,GenBank,ATV03510,,,O11,saeQ,,,,,,PHI:123352; PHI:123353,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,putative membrane protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20590,PHI:123352,UniProt,Q840P8,GenBank,CAD89110,,,Newman,saeR,,,,,,PHI:123351; PHI:123353,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,response regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20591,PHI:123353,UniProt,Q840P7,GenBank,CAD89111,,,Newman,saeS,,,,,,PHI:123351; PHI:123352,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,histidine kinase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20592,PHI:123354,UniProt,P0A074,GenBank,AAA26637,,,,hlgA,,,,,,PHI:123355; PHI:123356; PHI:123357; PHI:123358; PHI:123359; PHI:123360; PHI:123361,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,gamma-hemolysin component A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20593,PHI:123355,UniProt,Q07227,GenBank,AAA26638,,,,hlgC,,,,,,PHI:123354; PHI:123356; PHI:123357; PHI:123358; PHI:123359; PHI:123360; PHI:123361,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,gamma-hemolysin component C,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20594,PHI:123356,UniProt,P0A077,GenBank,AAA26639,,,,hlgB,,,,,,PHI:123354; PHI:123355; PHI:123357; PHI:123358; PHI:123359; PHI:123360; PHI:123361,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,gamma-hemolysin component B,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20595,PHI:123357,,no data found,,,,,,lukSF-PVL,,,,,,PHI:123354; PHI:123355; PHI:123356; PHI:123358; PHI:123359; PHI:123360; PHI:123361,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,panton-valentine leukocidin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20596,PHI:123358,,no data found,,,,,,lukA,,,,,,PHI:123354; PHI:123355; PHI:123356; PHI:123357; PHI:123359; PHI:123360; PHI:123361,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,leukocidin A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20597,PHI:123359,,no data found,,,,,,lukB,,,,,,PHI:123354; PHI:123355; PHI:123356; PHI:123357; PHI:123358; PHI:123360; PHI:123361,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,leukocidin B,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20598,PHI:123360,UniProt,O54081,GenBank,CAA73667,,,Newman,lukE,,,,,,PHI:123354; PHI:123355; PHI:123356; PHI:123357; PHI:123358; PHI:123359; PHI:123361,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,leukotoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20599,PHI:123361,UniProt,O54082,GenBank,CAA73668,,,Newman,lukD,,,,,,PHI:123354; PHI:123355; PHI:123356; PHI:123357; PHI:123358; PHI:123359; PHI:123360,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,peripheral blood mononuclear cell,leukotoxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: cluster,,,NN,35881802,PubMed,10.1073/pnas.2123017119,Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2123017119,Kelly.Ruggles@nyulangone.org,Muted transcriptional response was conserved across diverse S. aureus clones but absent in blood exposed to heat-killed S. aureus or blood infected with the less virulent staphylococcal species Staphylococcus epidermidis.,E E Zwack 2022,2022,11 genes,Zwack-2022-Staphylococcus aureus induces a mut,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20600,PHI:123362,,no data found,,,,,,Pi22798,,,,,,,4787,Phytophthora infestans,,88069,late blight (potato),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,larger lesions,,,,,no,,,,,,,functional test in host: transient expression,,,NN,35816329,PubMed,10.1093/jxb/erac308/6639838,J Exp Bot. 2022 Jul 11;erac308,tianzhd@mail.hzau.edu.cn,"Phytophthora infestans RxLR effector Pi22798 interacts in the nucleus with a potato class II knotted-like homeobox (KNOX) transcription factor, StKNOX3. Silencing the orthologue NbKNOX3 in Nicotiana benthamiana reduces host colonization by P. infestans, whereas transient and stable overexpression of StKNOX3 enhances infection. StKNOX3 forms a homodimer which is dependent on its KNOX II domain.",J Zhou 2022,2022,1 gene,Zhou-2022-A Phytophthora effector promotes hom,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20601,PHI:123362,,no data found,,,,,,Pi22798,,,,,,,4787,Phytophthora infestans,,88069,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Désirée,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,larger lesions,,,,,no,,,,,,,functional test in host: transient expression,,,NN,35816329,PubMed,10.1093/jxb/erac308/6639838,J Exp Bot. 2022 Jul 11;erac308,tianzhd@mail.hzau.edu.cn,"Phytophthora infestans RxLR effector Pi22798 interacts in the nucleus with a potato class II knotted-like homeobox (KNOX) transcription factor, StKNOX3. Silencing the orthologue NbKNOX3 in Nicotiana benthamiana reduces host colonization by P. infestans, whereas transient and stable overexpression of StKNOX3 enhances infection. StKNOX3 forms a homodimer which is dependent on its KNOX II domain.",J Zhou 2022,2022,1 gene,Zhou-2022-A Phytophthora effector promotes hom,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20602,PHI:123363,UniProt,Q75PN0,GenBank,BAD12447,,,NIH 18,cap60,,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,capsule protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35896747,PubMed,10.1038/s41586-022-05005-4,Nature. 2022 Aug;608(7921):161-167,hitenmadhani@gmail.com,"effector protein produced by a human fungal pathogen reprograms innate immunity, revealing an unexpected role for Toll-like receptor 4 in promoting the pathogenesis of infectious disease",E V Dang 2022,2022,2 genes,Dang-2022-Secreted fungal virulence effector t,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20603,PHI:123364,UniProt,J9VQE5,GenBank,AFR93895,,,H99,CPL1 (CNAG_02797),chromosome 3,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,effector protein,,,,reduced virulence,,,,,,,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35896747,PubMed,10.1038/s41586-022-05005-4,Nature. 2022 Aug;608(7921):161-167,hitenmadhani@gmail.com,"effector protein produced by a human fungal pathogen reprograms innate immunity, revealing an unexpected role for Toll-like receptor 4 in promoting the pathogenesis of infectious disease",E V Dang 2022,2022,2 genes,Dang-2022-Secreted fungal virulence effector t,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20604,PHI:123364,UniProt,J9VQE5,GenBank,AFR93895,,,H99,CPL1 (CNAG_02797),chromosome 3,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J (YARG),,,lung,effector protein,,,,reduced virulence,,,,,,,,,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35896747,PubMed,10.1038/s41586-022-05005-4,Nature. 2022 Aug;608(7921):161-167,hitenmadhani@gmail.com,"effector protein produced by a human fungal pathogen reprograms innate immunity, revealing an unexpected role for Toll-like receptor 4 in promoting the pathogenesis of infectious disease",E V Dang 2022,2022,2 genes,Dang-2022-Secreted fungal virulence effector t,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20605,PHI:123365,UniProt,A0A0F6B506,GenBank,ACY89597,,,14028S,steE,,,,,,,28901,Salmonella enterica,605,serovar Pullorum CVCC 530,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,macrophage,Salmonella anti-inflammatory response activator,,,,reduced virulence,,,yes,,,,,,,no,,,,,,,gene deletion: full,,,NN,35909683,PubMed,10.3389/fvets.2022.926505,Front Vet Sci. 2022 Jul 14;9:926505,tif_ua@meta.ua,ΔsteE significantly decreased colonization and long-term survival of the bacteria and alleviated pathological lesions compared to those in the wild-type,Z Liu 2022,2022,1 gene,Liu-2022-SteE Enhances the Virulence of Salmon,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20606,PHI:123365,UniProt,A0A0F6B506,GenBank,ACY89597,,,14028S,steE,,,,,,,28901,Salmonella enterica,605,serovar Pullorum CVCC 530,pullorum disease,birds,9031,Gallus gallus (related: chicken),cv. Jinghong,,,liver; spleen; bursa of Fabricius,Salmonella anti-inflammatory response activator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35909683,PubMed,10.3389/fvets.2022.926505,Front Vet Sci. 2022 Jul 14;9:926505,tif_ua@meta.ua,ΔsteE significantly decreased colonization and long-term survival of the bacteria and alleviated pathological lesions compared to those in the wild-type,Z Liu 2022,2022,1 gene,Liu-2022-SteE Enhances the Virulence of Salmon,BATCH_114A,2022-08-01,MC,,,,,,,,,,,,,
,,Record 20607,PHI:123373,UniProt,G4N5S6,GenBank,EHA53066,,,70-15,MoKns1 (MGG_16904),chromosome 3,,,MoATG18,UniProt: Q524W4; GenBank: EHA50539,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,CMGC/CLK protein kinase,,,,loss of pathogenicity,,,,,,reduced,,reduced; aberrant,,no,hydroxyurea; methyl methanesulfonate; rapamycin,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; rapamycin: CHEBI:9168,,,,,gene deletion: full; gene complementation,,,NN,35897680,PubMed,10.3390/ijms23158104,Int J Mol Sci. 2022 Jul 22;23(15):8104,fuchenglin@zju.edu.cn,"MoKNS1 deletion mutant, growth and conidiationwere primarily decreased, and pathogenicity was almost completely lost. MoKns1 interacted with the autophagy-related protein MoAtg18.",L Li 2022,2022,1 gene,Li-2022-The LAMMER Kinase MoKns1 Regulates Gro,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20608,PHI:123374,UniProt,Q7DB85,GenBank,AE005594_9,,,EDL933,EspF,,,,,,,562,Escherichia coli,155864,EDL933,urinary tract infection,primates,9606,Homo sapiens (related: human),HT-29 cell line,,,colorectal adenocarcinoma cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35847082,PubMed,10.3389/fmicb.2022.900919,Front Microbiol. 2022 Jun 30;13:900919.,gzwcs@smu.edu.cn,"The average apoptosis percentage (including late and early apoptosis) of the uninfected, WT, and espF deletion mutant infected groups was 24.34, 50.68, and 39.11%, respectively.",X Wang 2022,2022,1 gene,Wang-2022-EspF of Enterohemorrhagic Escherichi,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20609,PHI:123375,UniProt,A0A384JL35,GenBank,ATZ51084,,,B05.10,BcSpd1 (Bcin06g05230),chromosome BCIN06,,,,,,40559,Botrytis cinerea,332648,B05.10,gray mold,eudicots,3702,Arabidopsis thaliana (related: thale Cress),,,,leaf,Zn(2)-C6 fungal-type domain-containing protein,,,,reduced virulence,,,,yes,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35845699,PubMed,10.3389/fpls.2022.820767,Front Plant Sci. 2022 Jun 30;13:820767,shouan@jlu.edu.cn,"The BcSpd1 deletion mutant exhibited decreased infection cushion formation, and reduced virulence.",H Chen 2022,2022,1 gene,Chen-2022-The Necrotroph Botrytis cinerea BcSp,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20610,PHI:123375,UniProt,A0A384JL35,GenBank,ATZ51084,,,B05.10,BcSpd1 (Bcin06g05230),chromosome BCIN06,,,,,,40559,Botrytis cinerea,332648,B05.10,gray mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,Zn(2)-C6 fungal-type domain-containing protein,,,,reduced virulence,,,,yes,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35845699,PubMed,10.3389/fpls.2022.820767,Front Plant Sci. 2022 Jun 30;13:820767,shouan@jlu.edu.cn,"The BcSpd1 deletion mutant exhibited decreased infection cushion formation, and reduced virulence.",H Chen 2022,2022,1 gene,Chen-2022-The Necrotroph Botrytis cinerea BcSp,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20611,PHI:123375,UniProt,A0A384JL35,GenBank,ATZ51084,,,B05.10,BcSpd1 (Bcin06g05230),chromosome BCIN06,,,,,,40559,Botrytis cinerea,332648,B05.10,gray mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,Zn(2)-C6 fungal-type domain-containing protein,,,,reduced virulence,,,,yes,,,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,35845699,PubMed,10.3389/fpls.2022.820767,Front Plant Sci. 2022 Jun 30;13:820767,shouan@jlu.edu.cn,"The BcSpd1 deletion mutant exhibited decreased infection cushion formation, and reduced virulence.",H Chen 2022,2022,1 gene,Chen-2022-The Necrotroph Botrytis cinerea BcSp,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20612,PHI:123376,UniProt,R0K2C5,GenBank,EOA87293,,,Et28A,SRE1 (SETTUDRAFT_163271),chromosome unknown,,,,,,93612,Exserohilum turcicum,559306,TL-5,northern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,leaf,secretable RNase,,,,effector (plant avirulence determinant),,,,,,wild type,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,35875548,PubMed,10.3389/fmicb.2022.941991,Front Microbiol. 2022 Jul 8;13:941991,gaozenggui@sina.com,The knockdown SRE1 mutants caused milder symptoms in maize leaves than the wildtype strains 5 days after inoculation.,S He 2022,2022,1 gene,He-2022-The Secreted Ribonuclease SRE1 Contrib,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20613,PHI:123376,UniProt,R0K2C5,GenBank,EOA87293,,,Et28A,SRE1 (SETTUDRAFT_163271),chromosome unknown,SRE1 SP−Δ18−39−67A and SRE1 SP−67A,,,,,93612,Exserohilum turcicum,559306,TL-5,northern corn leaf blight,monocots,4577,Zea mays (related: maize),,,,leaf,secretable RNase,,,,effector (plant avirulence determinant),,,,,,wild type,,,,no,,,,,,,gene deletion: partial; gene mutation: characterised,,,NN,35875548,PubMed,10.3389/fmicb.2022.941991,Front Microbiol. 2022 Jul 8;13:941991,gaozenggui@sina.com,Two mutants with a mutation in the enzyme's active site lost all cytotoxicity in N. benthamiana.,S He 2022,2022,1 gene,He-2022-The Secreted Ribonuclease SRE1 Contrib,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20614,PHI:123377,,no data found,,,,,,cyt b,,G143A,,,,,5127,Fusarium fujikuroi,,LA-9; HQ-6,bakanae,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,cytochrome b,,,,reduced virulence,,,,,small lesions,reduced,,wild type,,no,,,,,,,gene mutation: characterised,,,NN,35901518,PubMed,10.1021/acs.jafc.2c02663,J Agric Food Chem. 2022 Aug 10;70(31):9760-9768,caohaiqun@ahau.edu.cn,"Azoxystrobin-resistant (AR) mutants having G143Ain cyt b showed decreased pathogenicity in tomato. Compared with the parental strains, the conidial production of only 2AR mutants HQ-6-R and LA-9-R decreased.",Y Song 2022,2022,1 gene,Song-2022-In Vitro Determination of Sensitivit,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20615,PHI:123377,,no data found,,,,,,cyt b,,G143A,,,,,5127,Fusarium fujikuroi,,LA-5; TL-2; HS-8,bakanae,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,cytochrome b,,,,reduced virulence,,,,,small lesions,wild type,,wild type,,no,,,,,,,gene mutation: characterised,,,NN,35901518,PubMed,10.1021/acs.jafc.2c02663,J Agric Food Chem. 2022 Aug 10;70(31):9760-9768,caohaiqun@ahau.edu.cn,Azoxystrobin-resistant (AR) mutants having G143Ain cyt b showed decreased pathogenicity in tomato. Compared with the parental strains there was no difference in mycelial growth or the conidial production of 2AR mutants.,Y Song 2022,2022,1 gene,Song-2022-In Vitro Determination of Sensitivit,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20616,PHI:123378,UniProt,I2EBS4,GenBank,AFJ97106,,,CX-3,ClNSP6,,,,,,,5503,Curvularia lunata,1263492,CX-3,Curvularia leaf spot,monocots,4577,Zea mays (related: maize),B73 line,,,leaf,nonribosomal peptide synthetase 6,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35867182,PubMed,10.1007/s00425-022-03963-7,Planta. 2022 Jul 22;256(3):46,xiaoshuqin@syau.edu.cn,The lesion number of various sizes on maize inoculated by ΔClnps6 was signifcantly less than those inoculated by CX-3.,D Fu 2022,2022,1 gene,Fu-2022-Iron redistribution induces oxidative,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20617,PHI:123379,UniProt,A0A0F6B259,GenBank,ACY88597,,,14028S,narK,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,nitrate/nitrite transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35806223,PubMed,10.3390/ijms23137220,Int J Mol Sci. 2022 Jun 29;23(13):7220,Int J Mol Sci. 2022 Jun 29;23(13):7220,The deletion mutation of narK significantly decreased the replication of S. Typhimurium in RAW264.7 cells.,W Li 2022,2022,3 genes,Li-2022-Nitrate Utilization Promotes Systemic,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20618,PHI:123380,UniProt,A0A0F6B4X5,GenBank,ACY89566,,,14028S,hmpA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,nitric oxide dioxygenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35806223,PubMed,10.3390/ijms23137220,Int J Mol Sci. 2022 Jun 29;23(13):7220,Int J Mol Sci. 2022 Jun 29;23(13):7220,The deletion mutation of hmpA significantly decreased the replication of S. Typhimurium in RAW264.7 cells.,W Li 2022,2022,3 genes,Li-2022-Nitrate Utilization Promotes Systemic,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20619,PHI:123381,UniProt,A0A0F6B1I9,GenBank,ACY88374,,,14028S,narU,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,nitrate/nitrite transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35806223,PubMed,10.3390/ijms23137220,Int J Mol Sci. 2022 Jun 29;23(13):7220,Int J Mol Sci. 2022 Jun 29;23(13):7220,The deletion mutation of narU did not significantly influence the replication ability of S. Typhimurium.,W Li 2022,2022,3 genes,Li-2022-Nitrate Utilization Promotes Systemic,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20620,PHI:123379,UniProt,A0A0F6B259,GenBank,ACY88597,,,14028S,narK,,,,,,PHI:123380,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,nitrate/nitrite transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35806223,PubMed,10.3390/ijms23137220,Int J Mol Sci. 2022 Jun 29;23(13):7220,Int J Mol Sci. 2022 Jun 29;23(13):7220,The double deletion mutation of narK/hmpA significantly decreased the replication of S. Typhimurium in RAW264.7 cells.,W Li 2022,2022,3 genes,Li-2022-Nitrate Utilization Promotes Systemic,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20621,PHI:123380,UniProt,A0A0F6B4X5,GenBank,ACY89566,,,14028S,hmpA,,,,,,PHI:123379,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,nitric oxide dioxygenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35806223,PubMed,10.3390/ijms23137220,Int J Mol Sci. 2022 Jun 29;23(13):7220,Int J Mol Sci. 2022 Jun 29;23(13):7220,The double deletion mutation of narK/hmpA significantly decreased the replication of S. Typhimurium in RAW264.7 cells.,W Li 2022,2022,3 genes,Li-2022-Nitrate Utilization Promotes Systemic,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20622,PHI:123379,UniProt,A0A0F6B259,GenBank,ACY88597,,,14028S,narK,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),,,,liver; spleen,nitrate/nitrite transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35806223,PubMed,10.3390/ijms23137220,Int J Mol Sci. 2022 Jun 29;23(13):7220,Int J Mol Sci. 2022 Jun 29;23(13):7220,The deletion mutation of narK significantly increased the the survival rate of the infected mice.,W Li 2022,2022,3 genes,Li-2022-Nitrate Utilization Promotes Systemic,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20623,PHI:123380,UniProt,A0A0F6B4X5,GenBank,ACY89566,,,14028S,hmpA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),,,,liver; spleen,nitric oxide dioxygenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35806223,PubMed,10.3390/ijms23137220,Int J Mol Sci. 2022 Jun 29;23(13):7220,Int J Mol Sci. 2022 Jun 29;23(13):7220,The deletion mutation of hmpA significantly increased the the survival rate of the infected mice.,W Li 2022,2022,3 genes,Li-2022-Nitrate Utilization Promotes Systemic,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20624,PHI:123381,UniProt,A0A0F6B1I9,GenBank,ACY88374,,,14028S,narU,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),,,,liver; spleen,nitrate/nitrite transporter,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35806223,PubMed,10.3390/ijms23137220,Int J Mol Sci. 2022 Jun 29;23(13):7220,Int J Mol Sci. 2022 Jun 29;23(13):7220,The deletion mutation of narU did not significantly influence the survival rate and bacterial burden in the livers and spleens of infected mice.,W Li 2022,2022,3 genes,Li-2022-Nitrate Utilization Promotes Systemic,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20625,PHI:123379,UniProt,A0A0F6B259,GenBank,ACY88597,,,14028S,narK,,,,,,PHI:123380,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),,,,liver; spleen,nitrate/nitrite transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35806223,PubMed,10.3390/ijms23137220,Int J Mol Sci. 2022 Jun 29;23(13):7220,Int J Mol Sci. 2022 Jun 29;23(13):7220,The double deletion mutation of narK/hmpA significantly increased the the survival rate of the infected mice.,W Li 2022,2022,3 genes,Li-2022-Nitrate Utilization Promotes Systemic,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20626,PHI:123380,UniProt,A0A0F6B4X5,GenBank,ACY89566,,,14028S,hmpA,,,,,,PHI:123379,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),,,,liver; spleen,nitric oxide dioxygenase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35806223,PubMed,10.3390/ijms23137220,Int J Mol Sci. 2022 Jun 29;23(13):7220,Int J Mol Sci. 2022 Jun 29;23(13):7220,The double deletion mutation of narK/hmpA significantly increased the the survival rate of the infected mice.,W Li 2022,2022,3 genes,Li-2022-Nitrate Utilization Promotes Systemic,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20627,PHI:123382,UniProt,A0A0A2LNP0,GenBank,KGO77925,,,PHI-1,PiCaMK1 (PITC_025800),,,,,,,40296,Penicillium italicum,,YN1,green mold,eudicots,85571,Citrus reticulata (related: tangerine),,,,fruit,calcium/calmodulin-dependent/calcium-dependent protein kinase,,,,reduced virulence,,,,,,reduced,,reduced; defective,,no,D-mannitol; NaCl; KCl; H2O2,D-mannitol: CHEBI:16899; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,35887424,PubMed,10.3390/jof8070667,J Fungi (Basel). 2022 Jun 25;8(7):667,yyz2007980080@ccnu.edu.cn,"The knockout mutant of PiCaMK1 showed a significant reduction in vegetative growth, conidiation, and virulence (i.e., to induce blue mold decay on citrus fruit).",G Li 2022,2022,1 gene,Li-2022-Characterization and Functional Analys,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20628,PHI:123393,UniProt,A0A448KH61,GenBank,VEG82718,,,NCTC11483,ulaA,chromosome 1,,,,,,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,skin,PTS system ascorbate-specific transporter subunits IICB,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,NN,35876728,PubMed,10.1093/infdis/jiac314,J Infect Dis. 2022 Jul 25;jiac314,jbrothwe@iu.edu,The deletion of ulaABCD did not impair the virulence of H. ducreyi in humans.,J A Brothwell 2022,2022,4 genes,Brothwell-2022-Ascorbic Acid Uptake and Utiliz,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20629,PHI:123394,,no data found,,,,,,ulaB,,,,,,,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,skin,phosphotransfer transporter,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,NN,35876728,PubMed,10.1093/infdis/jiac314,J Infect Dis. 2022 Jul 25;jiac314,jbrothwe@iu.edu,The deletion of ulaABCD did not impair the virulence of H. ducreyi in humans.,J A Brothwell 2022,2022,4 genes,Brothwell-2022-Ascorbic Acid Uptake and Utiliz,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20630,PHI:123395,UniProt,A0A448KH25,GenBank,VEG82717,,,NCTC11483,ulaC,chromosome 1,,,,,,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,skin,PTS system enzyme II-A permease,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,NN,35876728,PubMed,10.1093/infdis/jiac314,J Infect Dis. 2022 Jul 25;jiac314,jbrothwe@iu.edu,The deletion of ulaABCD did not impair the virulence of H. ducreyi in humans.,J A Brothwell 2022,2022,4 genes,Brothwell-2022-Ascorbic Acid Uptake and Utiliz,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20631,PHI:123396,UniProt,A0A448KH20,GenBank,VEG82716,,,NCTC11483,ulaD,chromosome 1,,,,,,730,Haemophilus ducreyi,233412,35000HP,chancroid,primates,9606,Homo sapiens (related: human),,,,skin,3-keto-L-gulonate-6-phosphate decarboxylase,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,NN,35876728,PubMed,10.1093/infdis/jiac314,J Infect Dis. 2022 Jul 25;jiac314,jbrothwe@iu.edu,The deletion of ulaABCD did not impair the virulence of H. ducreyi in humans.,J A Brothwell 2022,2022,4 genes,Brothwell-2022-Ascorbic Acid Uptake and Utiliz,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20632,PHI:123412,,no data found,,,,,,cteG,,,,,,,813,Chlamydia trachomatis,272561,D/UW-3/CX,sexually transmitted disease,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35903198,PubMed,10.3389/fcimb.2022.902210,Front Cell Infect Microbiol. 2022 Jul 8;12:902210,ljmota@fct.unl.pt,"CteG-dependent defect on host cell cytotoxicity was observed, indicating that CteG mediates chlamydial lytic exit.",I S Pereira 2022,2022,2 genes,Pereira-2022-The Type III Secretion Effector C,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20633,PHI:123413,UniProt,P0CE23,GenBank,CAB41600,,,L1/440/LN,Pgp4,,,,,,,813,Chlamydia trachomatis,272561,D/UW-3/CX,sexually transmitted disease,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,plasmid gene protein 4,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35903198,PubMed,10.3389/fcimb.2022.902210,Front Cell Infect Microbiol. 2022 Jul 8;12:902210,ljmota@fct.unl.pt,A C. trachomatis strain lacking Pgp4 was as defective in promoting host cell cytotoxicity.,I S Pereira 2022,2022,2 genes,Pereira-2022-The Type III Secretion Effector C,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20634,PHI:123412,,no data found,,,,,,cteG,,,,,,PHI:123413,813,Chlamydia trachomatis,272561,D/UW-3/CX,sexually transmitted disease,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,effector protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35903198,PubMed,10.3389/fcimb.2022.902210,Front Cell Infect Microbiol. 2022 Jul 8;12:902210,ljmota@fct.unl.pt,A C. trachomatis strain lacking both CteG and Pgp4 was as defective in promoting host cell cytotoxicity.,I S Pereira 2022,2022,2 genes,Pereira-2022-The Type III Secretion Effector C,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20635,PHI:123413,UniProt,P0CE23,GenBank,CAB41600,,,L1/440/LN,Pgp4,,,,,,PHI:123412,813,Chlamydia trachomatis,272561,D/UW-3/CX,sexually transmitted disease,primates,9606,Homo sapiens (related: human),HeLa 229 cell line,,,epithelial cell,plasmid gene protein 4,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35903198,PubMed,10.3389/fcimb.2022.902210,Front Cell Infect Microbiol. 2022 Jul 8;12:902210,ljmota@fct.unl.pt,A C. trachomatis strain lacking both CteG and Pgp4 was as defective in promoting host cell cytotoxicity.,I S Pereira 2022,2022,2 genes,Pereira-2022-The Type III Secretion Effector C,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20636,PHI:123414,UniProt,A0A022VQ83,GenBank,EZF48136,,,CBS 288.86,stuA,,,,,,,5551,Trichophyton rubrum,,CBS 118892,dermatophytosis,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,cell pattern formation-associated protein stuA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene disruption,,,NN,35783403,PubMed,10.3389/fmicb.2022.930398,Front Microbiol. 2022 Jun 17;13:930398,nmmrossi@usp.br,"Protease isoforms generated by alternative splicing in T. rubrum were also detected in a co-culture with human keratinocytes, highlighting the role of these proteins in keratin deconstruction",L Martins-Santana 2022,2022,1 gene,Martins-Santana-2022-Peptidase Regulation in T,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20637,PHI:123415,UniProt,Q1KS35,GenBank,ABE77154,,,,LvFABP (DQ459988),,,,,,,670,Vibrio parahaemolyticus,,VP-E1,acute hepatopancreatic necrosis disease,crustaceans,6689,Penaeus vannamei (related: Pacific white shrimp),,,,stomach; hepatopancreas; intestine,intracellular fatty acid binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,35860240,PubMed,10.3389/fimmu.2022.940405,Front Immunol. 2022 Jul 4;13:940405,leiwang@qdio.ac.cn,"L. vannamei. RNA interference (RNAi) of LvFABP reduced the mortality, histopathological signs of AHPND in the hepatopancreas, and the number of virulent VPAHPND bacteria in the intestine, stomach, and hepatopancreas after VPAHPND challenge.",X Gu 2022,2022,1 gene,Gu-2022-Identification and Expression Analysis,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20638,PHI:123416,UniProt,A3M7A4,GenBank,ABO12798,,,ATCC 17978,hdc,,,,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,histidine decarboxylase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene disruption,,,NN,35858582,PubMed,10.1159/000525536,J Innate Immun. 2022 Jul 20;1-21,k.dib @ qub.ac.uk,"H4R, but not the H2R, had no effect on the capture by neutrophils of serum-opsonized E. coli but significantly accelerated the intracellular killing of E. coli",K dib 2022,2022,1 gene,Dib-2022-Histamine Produced by Gram-Negative B,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20639,PHI:123417,,no data found,,,,,,AvrLm4-7 (Lmb_jn3_03262),,R100P; F102S; F102S G120R; S112R,,,,,5022,Leptosphaeria maculans,985895,JN3,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),cv. Pixel,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35793393,PubMed,10.1371/journal.ppat.1010664,PLoS Pathog. 2022 Jul 6;18(7):e1010664.,herman.van-tilbeurgh@i2bc.paris-saclay.fr,"In contrast, mutation S112R, located close to G120, was sufficient to escape Rlm4 and Rlm7-mediated recog-nition and abolish the ability of AvrLm4-7 to suppress Rlm3-mediated recognition of AvrLm3.",N Lazar 2022,2022,2 genes,Lazar-2022-A new family of structurally conser,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20640,PHI:123417,,no data found,,,,,,AvrLm4-7 (Lmb_jn3_03262),,R100P; F102S; F102S G120R; S112R,,,,,5022,Leptosphaeria maculans,985895,JN3,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),15.22.4.1 line,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35793393,PubMed,10.1371/journal.ppat.1010664,PLoS Pathog. 2022 Jul 6;18(7):e1010664.,herman.van-tilbeurgh@i2bc.paris-saclay.fr,"Mutations R100P and F102S led to a switch to virulence towards Rlm7 cultivar and abolished the ability of AvrLm4-7 to suppress Rlm3-mediated recognition of AvrLm3 when they were combined with a G120R mutation, suggesting that both R100 or F102 and G120 are necessary to mask AvrLm3 recognition",N Lazar 2022,2022,2 genes,Lazar-2022-A new family of structurally conser,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20641,PHI:123417,,no data found,,,,,,AvrLm4-7 (Lmb_jn3_03262),,R100P; F102S; F102S G120R; S112R,,,,,5022,Leptosphaeria maculans,985895,JN3,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),15.23.4.1 line,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35793393,PubMed,10.1371/journal.ppat.1010664,PLoS Pathog. 2022 Jul 6;18(7):e1010664.,herman.van-tilbeurgh@i2bc.paris-saclay.fr,"In contrast, mutation S112R, located close to G120, was sufficient to escape Rlm4 and Rlm7-mediated recog-nition and abolish the ability of AvrLm4-7 to suppress Rlm3-mediated recognition of AvrLm3.",N Lazar 2022,2022,2 genes,Lazar-2022-A new family of structurally conser,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20642,PHI:123418,UniProt,A0A1P8YXI8,GenBank,AQA29221,,,OWU,ECP11-1,,,,,,,5499,Fulvia fulva,,,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),cv. Pixel,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35793393,PubMed,10.1371/journal.ppat.1010664,PLoS Pathog. 2022 Jul 6;18(7):e1010664.,herman.van-tilbeurgh@i2bc.paris-saclay.fr,"All transformants, as the wild type isolates, were virulent on Pixel",N Lazar 2022,2022,2 genes,Lazar-2022-A new family of structurally conser,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20643,PHI:123418,UniProt,A0A1P8YXI8,GenBank,AQA29221,,,OWU,ECP11-1,,,,,,,5499,Fulvia fulva,,,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),15.22.4.1 line,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35793393,PubMed,10.1371/journal.ppat.1010664,PLoS Pathog. 2022 Jul 6;18(7):e1010664.,herman.van-tilbeurgh@i2bc.paris-saclay.fr,"Differing from their parental isolates, all transformants were avirulent on 15.22.4.1",N Lazar 2022,2022,2 genes,Lazar-2022-A new family of structurally conser,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20644,PHI:123418,UniProt,A0A1P8YXI8,GenBank,AQA29221,,,OWU,ECP11-1,,,,,,,5499,Fulvia fulva,,,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),15.23.4.1 line,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35793393,PubMed,10.1371/journal.ppat.1010664,PLoS Pathog. 2022 Jul 6;18(7):e1010664.,herman.van-tilbeurgh@i2bc.paris-saclay.fr,"Inoculated transformants on the oilseed rape line 15.23.4.1, a sister line of 15.22.4.1 also issued from individual plants from cv. Rangi, carrying Rlm7 instead of Rlm3, and obtained a susceptibility phenotype",N Lazar 2022,2022,2 genes,Lazar-2022-A new family of structurally conser,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20645,PHI:123418,UniProt,A0A1P8YXI8,GenBank,AQA29221,,,OWU,ECP11-1,,,,,,,5499,Fulvia fulva,,,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),18.22.6.1 line,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35793393,PubMed,10.1371/journal.ppat.1010664,PLoS Pathog. 2022 Jul 6;18(7):e1010664.,herman.van-tilbeurgh@i2bc.paris-saclay.fr,"15.23.4.1 and 18.22.6.1 are two sister lines issued from indi-vidual plants from cv. Rangi that showed a contrasted behavior when inoculated with AvrLm7or AvrLm3 isolates, respectively.",N Lazar 2022,2022,2 genes,Lazar-2022-A new family of structurally conser,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20646,PHI:123418,UniProt,A0A1P8YXI8,GenBank,AQA29221,,,OWU,ECP11-1,,,,,,,5499,Fulvia fulva,,,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),cv. Grizzly,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35793393,PubMed,10.1371/journal.ppat.1010664,PLoS Pathog. 2022 Jul 6;18(7):e1010664.,herman.van-tilbeurgh@i2bc.paris-saclay.fr,Unrelated oilseed rape cultivars carrying Rlm3 (Grizzly and Columbus) confirmed a resistance phenotype on these cultivars triggered by Ecp11-1,N Lazar 2022,2022,2 genes,Lazar-2022-A new family of structurally conser,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20647,PHI:123418,UniProt,A0A1P8YXI8,GenBank,AQA29221,,,OWU,ECP11-1,,,,,,,5499,Fulvia fulva,,,stem canker (oilseed rape),eudicots,3708,Brassica napus (related: rape),cv. Columbus,,,cotyledon,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,heterologous expression,,,NN,35793393,PubMed,10.1371/journal.ppat.1010664,PLoS Pathog. 2022 Jul 6;18(7):e1010664.,herman.van-tilbeurgh@i2bc.paris-saclay.fr,Unrelated oilseed rape cultivars carrying Rlm3 (Grizzly and Columbus) confirmed a resistance phenotype on these cultivars triggered by Ecp11-1,N Lazar 2022,2022,2 genes,Lazar-2022-A new family of structurally conser,BATCH_114B,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20648,PHI:123383,UniProt,Q9S3T6,GenBank,AAD51711,,,307; RN8160,agrA,,,,,,,28035,Staphylococcus lugdunensis,,Sl44,infective endocarditis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,35138170,PubMed,10.1128/spectrum.01598-21,Microbiol Spectr. 2022 Feb 23;10(1):e0159821,jean-christophe.giard@unicaen.fr,"ΔargA mutant colonies were white while the parental strains were slightly yellow. Compared with the wild-type strain, the ΔargA mutant was affected in its ability to form biofilm and was less able to survive in mice macrophages indicating reduced virulence.",M Aubourg 2022,2022,1 gene,Aubourg-2022-Inactivation of the Response Regu,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20649,PHI:123384,UniProt,P66719,GenBank,AAK34603,,,5005,RopE (M5005_Spy_1611),,,,,,,1314,Streptococcus pyogenes,530008,serotype M1 strain 5448,infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,hindlimb,probable DNA-directed RNA polymerase subunit delta,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,gene mutation: characterised,,,NN,36014103,PubMed,10.3390/microorganisms10081686,Microorganisms. 2022 Aug 22;10(8):1686,kmciver@umd.edu,"All mice infected with WT 5448 succumbed by day 5, whereas all but one mouse from the group infected with the rpoE mutant survived the seven-day time course of the experiment.",J S Rom 2022,2022,1 gene,Rom-2022-Loss of rpoE Encoding the δ-Factor of,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20650,PHI:123384,UniProt,P66719,GenBank,AAK34603,,,5005,RopE (M5005_Spy_1611),,,,,,,1314,Streptococcus pyogenes,530008,serotype M1 strain 5448,infection,rodents,10090,Mus musculus (related: house mouse),Crl:SKH1-hrBR,,,skin; soft-tissue,probable DNA-directed RNA polymerase subunit delta,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,gene mutation: characterised,,,NN,36014103,PubMed,10.3390/microorganisms10081686,Microorganisms. 2022 Aug 22;10(8):1686,kmciver@umd.edu,Mutation of rpoE reduces the ability of GAS to proliferate inside the host.,J S Rom 2022,2022,1 gene,Rom-2022-Loss of rpoE Encoding the δ-Factor of,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20651,PHI:123384,UniProt,P66719,GenBank,AAK34603,,,5005,RopE (M5005_Spy_1611),,,,,,,1314,Streptococcus pyogenes,530008,serotype M1 strain 5448,infection,primates,9606,Homo sapiens (related: human),,,,blood,probable DNA-directed RNA polymerase subunit delta,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,gene mutation: characterised,,,NN,36014103,PubMed,10.3390/microorganisms10081686,Microorganisms. 2022 Aug 22;10(8):1686,kmciver@umd.edu,Mutation of rpoE significantly reduced GAS recovered after 3 h incubation in non-immune human blood by comparison to the WT 5448,J S Rom 2022,2022,1 gene,Rom-2022-Loss of rpoE Encoding the δ-Factor of,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20652,PHI:123385,UniProt,A0A0D1C6B8,GenBank,KIS69182,,,521,UMAG_02533,chromosome 6,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,auxin signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,35944559,PubMed,10.1111/nph.18315,New Phytol. 2022 Aug 9,djamei@uni-bonn.de,Deletion of gene cluster of effector 6A causes significant reduction of virulence.,J Bindics 2022,2022,8 genes,Bindics-2022-Many ways to TOPLESS - manipulati,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20653,PHI:123386,UniProt,A0A0D1CRF7,GenBank,KIS69183,,,521,UMAG_11415,chromosome 6,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,auxin signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,35944559,PubMed,10.1111/nph.18315,New Phytol. 2022 Aug 9,djamei@uni-bonn.de,Deletion of gene cluster of effector 6A causes significant reduction of virulence.,J Bindics 2022,2022,8 genes,Bindics-2022-Many ways to TOPLESS - manipulati,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20654,PHI:123387,UniProt,A0A0D1DYP1,GenBank,KIS69184,,,521,UMAG_02535,chromosome 6,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,auxin signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,35944559,PubMed,10.1111/nph.18315,New Phytol. 2022 Aug 9,djamei@uni-bonn.de,Deletion of gene cluster of effector 6A causes significant reduction of virulence.,J Bindics 2022,2022,8 genes,Bindics-2022-Many ways to TOPLESS - manipulati,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20655,PHI:123388,UniProt,A0A0D1E3X3,GenBank,KIS69185,,,521,UMAG_11416,chromosome 6,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,auxin signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,35944559,PubMed,10.1111/nph.18315,New Phytol. 2022 Aug 9,djamei@uni-bonn.de,Deletion of gene cluster of effector 6A causes significant reduction of virulence.,J Bindics 2022,2022,8 genes,Bindics-2022-Many ways to TOPLESS - manipulati,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20656,PHI:123389,UniProt,A0A0D1DZX5,GenBank,KIS69186,,,521,UMAG_02537,chromosome 6,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,auxin signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,35944559,PubMed,10.1111/nph.18315,New Phytol. 2022 Aug 9,djamei@uni-bonn.de,Deletion of gene cluster of effector 6A causes significant reduction of virulence.,J Bindics 2022,2022,8 genes,Bindics-2022-Many ways to TOPLESS - manipulati,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20657,PHI:123390,UniProt,A0A0D1C6C3,GenBank,KIS69187,,,521,UMAG_02538,chromosome 6,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,auxin signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,35944559,PubMed,10.1111/nph.18315,New Phytol. 2022 Aug 9,djamei@uni-bonn.de,Deletion of gene cluster of effector 6A causes significant reduction of virulence.,J Bindics 2022,2022,8 genes,Bindics-2022-Many ways to TOPLESS - manipulati,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20658,PHI:123391,UniProt,A0A0D1CRG2,GenBank,KIS69188,,,521,UMAG_11417,chromosome 6,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,auxin signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,35944559,PubMed,10.1111/nph.18315,New Phytol. 2022 Aug 9,djamei@uni-bonn.de,Deletion of gene cluster of effector 6A causes significant reduction of virulence.,J Bindics 2022,2022,8 genes,Bindics-2022-Many ways to TOPLESS - manipulati,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20659,PHI:123392,UniProt,A0A0D1DYP7,GenBank,KIS69189,,,521,UMAG_02540,chromosome 6,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,auxin signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,35944559,PubMed,10.1111/nph.18315,New Phytol. 2022 Aug 9,djamei@uni-bonn.de,Deletion of gene cluster of effector 6A causes significant reduction of virulence.,J Bindics 2022,2022,8 genes,Bindics-2022-Many ways to TOPLESS - manipulati,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20660,PHI:123385,UniProt,A0A0D1C6B8,GenBank,KIS69182,,,521,UMAG_02533,chromosome 6,,,,,PHI:123392,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,auxin signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,35944559,PubMed,10.1111/nph.18315,New Phytol. 2022 Aug 9,djamei@uni-bonn.de,The UMAG_02533/UMAG_02540 double knockout strain showed full virulence,J Bindics 2022,2022,8 genes,Bindics-2022-Many ways to TOPLESS - manipulati,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20661,PHI:123392,UniProt,A0A0D1DYP7,GenBank,KIS69189,,,521,UMAG_02540,chromosome 6,,,,,PHI:123385,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,effector (plant avirulence determinant),,,auxin signalling,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,35944559,PubMed,10.1111/nph.18315,New Phytol. 2022 Aug 9,djamei@uni-bonn.de,The UMAG_02533/UMAG_02540 double knockout strain showed full virulence,J Bindics 2022,2022,8 genes,Bindics-2022-Many ways to TOPLESS - manipulati,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20662,PHI:123397,UniProt,M9RZ23,GenBank,AGI78467,,,01-23,StPkaC1,,,,StFlo8,,,93612,Exserohilum turcicum,559306,2023,northern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. OH43,,,leaf,protein kinase A catalytic subunit,,,,reduced virulence,,,,yes,,defective,,wild type,,no,,,,,,,gene deletion: full,,,NN,35929228,PubMed,10.1111/mpp.13253,Mol Plant Pathol. 2022 Aug 5,haozhimin@hebau.edu.cn,StPkaC1 specifically interacts with a transcriptional regulator StFlo8. ΔStPkaC2 showed reduced virulence.,Y Liu 2022,2022,2 genes,Liu-2022-Protein kinase A participates in hyph,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20663,PHI:123398,,no data found,,,,,,StPkaC2,,,,StEfg1,UniProt: R0JUF5; GenBank: EOA84633,,93612,Exserohilum turcicum,559306,2023,northern corn leaf blight,monocots,4577,Zea mays (related: maize),cv. OH43,,,leaf,protein kinase A catalytic subunit,,,,loss of pathogenicity,,yes,,yes,,defective,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35929228,PubMed,10.1111/mpp.13253,Mol Plant Pathol. 2022 Aug 5,haozhimin@hebau.edu.cn,StPkaC2 specifically interacts with StEfg1. ΔStPkaC2 is defective in appressorium development and has completely lost its pathogenicity.,Y Liu 2022,2022,2 genes,Liu-2022-Protein kinase A participates in hyph,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20664,PHI:123399,UniProt,G4MKC3,GenBank,EHA56714,,,70-15,DHX35 (MGG_02518),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ATP-dependent RNA helicase,,,,reduced virulence,,,,,,wild type,wild type,wild type,wild type,no,calcofluor white (CFW); carbendazim; NaCl; cycloheximide,calcofluor white (CFW): CHEBI:50011; carbendazim: CHEBI:3392; NaCl: CHEBI:267101; cycloheximide: CHEBI:27641,,,,,gene deletion: full; gene complementation,,,NN,36012276,PubMed,10.3390/ijms23169015,Int J Mol Sci. 2022 Aug 12;23(16):9015,wangjiaoyu78@sina.com,"MoDHX35-deleted mutants exhibited normal vegetative growth, conidia generation and conidial germination, but showed a reduced appressorium formation rate and attenuated virulence.",S Ying 2022,2022,1 gene,"Ying-2022-MoDHX35, a DEAH-Box Protein, Is Requ",BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20665,PHI:123399,UniProt,G4MKC3,GenBank,EHA56714,,,70-15,DHX35 (MGG_02518),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ATP-dependent RNA helicase,,,,reduced virulence,,,,,,wild type,wild type,wild type,wild type,no,calcofluor white (CFW); carbendazim; NaCl; cycloheximide,calcofluor white (CFW): CHEBI:50011; carbendazim: CHEBI:3392; NaCl: CHEBI:267101; cycloheximide: CHEBI:27641,,,,,gene deletion: full; gene complementation,,,NN,36012276,PubMed,10.3390/ijms23169015,Int J Mol Sci. 2022 Aug 12;23(16):9015,wangjiaoyu78@sina.com,MoDHX35-deleted mutants reduced appressorium formation rate and attenuated virulence in barley leaves.,S Ying 2022,2022,1 gene,"Ying-2022-MoDHX35, a DEAH-Box Protein, Is Requ",BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20666,PHI:123400,UniProt,P0CT49,GenBank,EHA53393,,,70-15,MoXYL1A (MGG_07955),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,"endo-beta-1,4-xylanase I",,,,loss of pathogenicity,,yes,yes,,no blast lesion,reduced,,wild type,,no,calcofluor white (CFW); SDS; Congo red,calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35960402,PubMed,10.1186/s12284-022-00584-2,Rice (N Y). 2022 Aug 12;15(1):44,wangzh@fafu.edu.cn,ΔMoxyl1A strains showed that MoXYL1A is required for the full virulence of M. oryzae but is dispensable for the vegetative growth of the rice blast fungus.,A Shabbir 2022,2022,2 genes,Shabbir-2022-Magnaporthe oryzae Chloroplast Ta,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20667,PHI:123400,UniProt,P0CT49,GenBank,EHA53393,,,70-15,MoXYL1A (MGG_07955),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,seedling,"endo-beta-1,4-xylanase I",,,,loss of pathogenicity,,yes,yes,,no blast lesion,reduced,,wild type,,no,calcofluor white (CFW); SDS; Congo red,calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35960402,PubMed,10.1186/s12284-022-00584-2,Rice (N Y). 2022 Aug 12;15(1):44,wangzh@fafu.edu.cn,ΔMoxyl1A strains showed that MoXYL1A is required for the full virulence of M. oryzae but is dispensable for the vegetative growth of the rice blast fungus.,A Shabbir 2022,2022,2 genes,Shabbir-2022-Magnaporthe oryzae Chloroplast Ta,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20668,PHI:123401,UniProt,G4NA54,GenBank,EHA49604,,,70-15,MoXYL1B (MGG_08424),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,seedling,"endo-1,4-beta-xylanase 4",,,,unaffected pathogenicity,,no,no,,typical blast lesions,reduced,,wild type,,no,calcofluor white (CFW); SDS; Congo red,calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35960402,PubMed,10.1186/s12284-022-00584-2,Rice (N Y). 2022 Aug 12;15(1):44,wangzh@fafu.edu.cn,ΔMoxyl1B produced conidiophores of WT shape but in reduced number relative to WT. ΔMoxyl1B produced typical blast lesions,A Shabbir 2022,2022,2 genes,Shabbir-2022-Magnaporthe oryzae Chloroplast Ta,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20669,PHI:123401,UniProt,G4NA54,GenBank,EHA49604,,,70-15,MoXYL1B (MGG_08424),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,"endo-1,4-beta-xylanase 4",,,,unaffected pathogenicity,,no,no,,typical blast lesions,reduced,,wild type,,no,calcofluor white (CFW); SDS; Congo red,calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,35960402,PubMed,10.1186/s12284-022-00584-2,Rice (N Y). 2022 Aug 12;15(1):44,wangzh@fafu.edu.cn,ΔMoxyl1B produced conidiophores of WT shape but in reduced number relative to WT. ΔMoxyl1B produced typical blast lesions,A Shabbir 2022,2022,2 genes,Shabbir-2022-Magnaporthe oryzae Chloroplast Ta,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20670,PHI:123400,UniProt,P0CT49,GenBank,EHA53393,,,70-15,MoXYL1A (MGG_07955),chromosome 3,,,,,PHI:123401,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,seedling,"endo-beta-1,4-xylanase I",,,,loss of pathogenicity,,yes,yes,,no blast lesion,reduced,,wild type,,no,calcofluor white (CFW); SDS; Congo red,calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35960402,PubMed,10.1186/s12284-022-00584-2,Rice (N Y). 2022 Aug 12;15(1):44,wangzh@fafu.edu.cn,ΔMoxyl1A/ ΔMoxyl1B double mutant strains showed loss of virulence virulence of M. oryzae.,A Shabbir 2022,2022,2 genes,Shabbir-2022-Magnaporthe oryzae Chloroplast Ta,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20671,PHI:123401,UniProt,G4NA54,GenBank,EHA49604,,,70-15,MoXYL1B (MGG_08424),chromosome 4,,,,,PHI:123400,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,seedling,"endo-1,4-beta-xylanase 4",,,,loss of pathogenicity,,yes,yes,,no blast lesion,reduced,,wild type,,no,calcofluor white (CFW); SDS; Congo red,calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35960402,PubMed,10.1186/s12284-022-00584-2,Rice (N Y). 2022 Aug 12;15(1):44,wangzh@fafu.edu.cn,ΔMoxyl1A/ ΔMoxyl1B double mutant strains showed loss of virulence virulence of M. oryzae.,A Shabbir 2022,2022,2 genes,Shabbir-2022-Magnaporthe oryzae Chloroplast Ta,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20672,PHI:123402,UniProt,G4N022,GenBank,EHA52260,,,70-15,MoSCS2 (MGG_06183),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,MSP domain-containing protein,,,,reduced virulence,,yes,yes,yes,reduced blast lesion,reduced; aberrant,,reduced,,no,calcofluor white (CFW); SDS; Congo red; dithiothreitol; tunicamycin,calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; Congo red: CHEBI:34653; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699,,,,,gene deletion: full; gene complementation,,,NN,35992683,PubMed,10.3389/fmicb.2022.906784,Front Microbiol. 2022 Aug 4;13:906784,tangw@fafu.edu.cn,ΔMoscs2 showed a significant reduction in growth and conidiation. The ΔMoscs2 mutant showed delayed appressorium formation Significant reduction in pathogenicity was found in ΔMoscs2 mutants.,J Zhang 2022,2022,1 gene,Zhang-2022-Endoplasmic reticulum membrane prot,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20673,PHI:123402,UniProt,G4N022,GenBank,EHA52260,,,70-15,MoSCS2 (MGG_06183),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,seedling,MSP domain-containing protein,,,,reduced virulence,,yes,yes,yes,reduced blast lesion,reduced; aberrant,,reduced,,no,calcofluor white (CFW); SDS; Congo red; dithiothreitol; tunicamycin,calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; Congo red: CHEBI:34653; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699,,,,,gene deletion: full; gene complementation,,,NN,35992683,PubMed,10.3389/fmicb.2022.906784,Front Microbiol. 2022 Aug 4;13:906784,tangw@fafu.edu.cn,ΔMoscs2 showed a significant reduction in growth and conidiation. The ΔMoscs2 mutant showed delayed appressorium formation Significant reduction in pathogenicity was found in ΔMoscs2 mutants.,J Zhang 2022,2022,1 gene,Zhang-2022-Endoplasmic reticulum membrane prot,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20674,PHI:123403,UniProt,Q9I035,GenBank,AAG06196,,,PAO1,PtrA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,repressor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35959145,PubMed,10.2147/IDR.S371597,Infect Drug Resist. 2022 Aug 4;15:4213-4227,wyztli@163.com,The capacity of the PtrA mutant to adhere and invade RAW264.7 cells was found to be weaker than that of the WT strain.,Y Zhang 2022,2022,1 gene,Zhang-2022-Novel Insight of Transcription Fact,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20675,PHI:123403,UniProt,Q9I035,GenBank,AAG06196,,,PAO1,PtrA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,repressor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35959145,PubMed,10.2147/IDR.S371597,Infect Drug Resist. 2022 Aug 4;15:4213-4227,wyztli@163.com,"The survival rates of the WT strains under the ame inoculation doses were markedly reduced, compared to the ptrA mutation strain.",Y Zhang 2022,2022,1 gene,Zhang-2022-Novel Insight of Transcription Fact,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20676,PHI:123404,UniProt,J4W0P2,GenBank,EJP64095,,,ARSEF 2860,BbElp3 (EJP64095),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,elongator complex protein 3,,,,reduced virulence,,,yes,,,reduced; aberrant,,reduced; aberrant,,no,NaCl; KCl; H2O2; hydroxyurea; methyl methanesulfonate; rapamycin; SDS; Congo red; menadione; carbendazim; iprodione,NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; rapamycin: CHEBI:9168; SDS: CHEBI:8984; Congo red: CHEBI:34653; menadione: CHEBI:28869; carbendazim: CHEBI:3392; iprodione: CHEBI:28909,,,,,gene deletion: full; gene complementation,,,NN,36012822,PubMed,10.3390/jof8080834,mSystems.2020 Apr 21;5(2):e00677-19,J Fungi (Basel). 2022 Aug 10;8(8):834,"Targeted gene knockout of BbElp3 resulted in impaired asexual development and morphogenesis, reduced tolerances to multiple stress conditions, reduced the ability of the fungus to utilize various carbon/nitrogen sources, increased susceptibility to rapamycin, and attenuated virulence in bioassays using the greater wax moth, Galleria mellonella.",Q Cai 2022,2022,1 gene,Cai-2022-The Elongator Subunit Elp3 Regulates,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20677,PHI:123405,UniProt,G4MSW9,GenBank,EHA53823,,,70-15,Moade4 (MGG_04618),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,seedling,amidophosphoribosyltransferase,,,,loss of pathogenicity,,no,,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35918446,PubMed,10.1007/s00253-022-12100-z,Appl Microbiol Biotechnol. 2022 Sep;106(17):5587-5602,wangzh@fafu.edu.cn,Pathogenicity tests showed that ΔMoade4 was completely nonpathogenic on rice and barley leaves.,O Aron 2022,2022,1 gene,Aron-2022-De novo purine nucleotide biosynthes,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20678,PHI:123405,UniProt,G4MSW9,GenBank,EHA53823,,,70-15,Moade4 (MGG_04618),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,seedling,amidophosphoribosyltransferase,,,,loss of pathogenicity,,no,,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35918446,PubMed,10.1007/s00253-022-12100-z,Appl Microbiol Biotechnol. 2022 Sep;106(17):5587-5602,wangzh@fafu.edu.cn,Pathogenicity tests showed that ΔMoade4 was completely nonpathogenic on rice and barley leaves.,O Aron 2022,2022,1 gene,Aron-2022-De novo purine nucleotide biosynthes,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20679,PHI:123406,UniProt,Q4WN24,GenBank,EAL88640,,,Af293,GemA (Afu 6g07870),chromosome 6,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,mitochondrial Rho GTPase 1,,,,reduced virulence,,,,,,reduced; defective,,reduced,,no,voriconazole; itraconazole; amphotericin B; bifonazole; terbinafine,voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; amphotericin B: CHEBI:2682; bifonazole: CHEBI:31286; terbinafine: CHEBI:9448,,,,,gene deletion: full; gene complementation,,,NN,36016773,PubMed,10.3389/fmicb.2022.957857,Front Microbiol. 2022 Aug 9;13:957857,xuelianchang@126.com,"Loss of gemA results in aberrant giant mitochondrial morphology and abnormal mitochondrial membrane potential. Moreover, a ΔgemA mutant attenuates fungal virulence in the Galleria mellonella model of aspergillosis",X Zhor 2022,2022,1 gene,Zhou-2022-Requirement of a putative mitochondr,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20680,PHI:123407,UniProt,A0A0H2V722,GenBank,AAN80222,,,CFT073,yciR,,,,HupB,UniProt: P0ACF5; GenBank: AAN79034,,562,Escherichia coli,,CFT073,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,bladder,3'-phosphodiesterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35923408,PubMed,10.3389/fmicb.2022.910906,Front Microbiol. 2022 Jul 18;13:910906,duyuhui_107@163.com,Bacterial titers in bladders infected by ΔyciR were significantly lower than those in bladders infected by the wild type.,S Zhang 2022,2022,1 gene,"Zhang-2022-YciR, a Specific 3'-Phosphodiestera",BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20681,PHI:123407,UniProt,A0A0H2V722,GenBank,AAN80222,,,CFT073,yciR,,,,HupB,UniProt: P0ACF5; GenBank: AAN79034,,562,Escherichia coli,,CFT073,urinary tract infection,primates,9606,Homo sapiens (related: human),5637 cell line,,,urinary bladder epithelium,3'-phosphodiesterase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35923408,PubMed,10.3389/fmicb.2022.910906,Front Microbiol. 2022 Jul 18;13:910906,duyuhui_107@163.com,ΔyciR exhibited a decreasing ability to invade the 5637 bladder cell line compared with the Wwild type.,S Zhang 2022,2022,1 gene,"Zhang-2022-YciR, a Specific 3'-Phosphodiestera",BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20682,PHI:123408,UniProt,A0A8D4A156,GenBank,AML46688,,,NSUI060,lacD,,,,,,,1307,Streptococcus suis,,HA9801,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),BALB/c,,,blood,"tagatose 1,6-diphosphate aldolase",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; ciprofloxacin; ampicillin; streptomycin sulfate; gentamicin; chloramphenicol; trimethoprim; sulfamethoxazole; kanamycin; ceftiofur; tetracycline,H2O2: CHEBI:16240; ciprofloxacin: CHEBI:100241; ampicillin: CHEBI:28971; streptomycin sulfate: CHEBI:32158; gentamicin: CHEBI:17833; chloramphenicol: CHEBI:17698; trimethoprim: CHEBI:45924; sulfamethoxazole: CHEBI:9332; kanamycin: CHEBI:6104; ceftiofur: CHEBI:31383; tetracycline: CHEBI:27902,,,,,gene deletion: full; gene complementation,,,NN,35984615,PubMed,10.1007/s12275-022-2146-4,J Microbiol. 2022 Sep;60(9):948-959,xwjiang@zju.edu.cn,The lacD gene deletion showed no effect on growth capability and cells morphology of Streptococcus suis serotype 2. The LacD deficiency led to weakened invasion and attenuated virulence.,X Jiang 2022,2022,1 gene,Jiang-2022-Deletion of lacD gene affected stre,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20683,PHI:123408,UniProt,A0A8D4A156,GenBank,AML46688,,,NSUI060,lacD,,,,,,,1307,Streptococcus suis,,HA9801,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,"tagatose 1,6-diphosphate aldolase",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; ciprofloxacin; ampicillin; streptomycin sulfate; gentamicin; chloramphenicol; trimethoprim; sulfamethoxazole; kanamycin; ceftiofur; tetracycline,H2O2: CHEBI:16240; ciprofloxacin: CHEBI:100241; ampicillin: CHEBI:28971; streptomycin sulfate: CHEBI:32158; gentamicin: CHEBI:17833; chloramphenicol: CHEBI:17698; trimethoprim: CHEBI:45924; sulfamethoxazole: CHEBI:9332; kanamycin: CHEBI:6104; ceftiofur: CHEBI:31383; tetracycline: CHEBI:27902,,,,,gene deletion: full; gene complementation,,,NN,35984615,PubMed,10.1007/s12275-022-2146-4,J Microbiol. 2022 Sep;60(9):948-959,xwjiang@zju.edu.cn,LacD factor deficiency rendered the bacteria more easily phagocytosed to RAW 264.7 cells than the WT strain.,X Jiang 2022,2022,1 gene,Jiang-2022-Deletion of lacD gene affected stre,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20684,PHI:123408,UniProt,A0A8D4A156,GenBank,AML46688,,,NSUI060,lacD,,,,,,,1307,Streptococcus suis,,HA9801,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),bEnd.3 cell line,,,bEnd3 cell,"tagatose 1,6-diphosphate aldolase",,,,reduced virulence,,,,,,,,wild type,,no,H2O2; ciprofloxacin; ampicillin; streptomycin sulfate; gentamicin; chloramphenicol; trimethoprim; sulfamethoxazole; kanamycin; ceftiofur; tetracycline,H2O2: CHEBI:16240; ciprofloxacin: CHEBI:100241; ampicillin: CHEBI:28971; streptomycin sulfate: CHEBI:32158; gentamicin: CHEBI:17833; chloramphenicol: CHEBI:17698; trimethoprim: CHEBI:45924; sulfamethoxazole: CHEBI:9332; kanamycin: CHEBI:6104; ceftiofur: CHEBI:31383; tetracycline: CHEBI:27902,,,,,gene deletion: full; gene complementation,,,NN,35984615,PubMed,10.1007/s12275-022-2146-4,J Microbiol. 2022 Sep;60(9):948-959,xwjiang@zju.edu.cn,Gene deletion of lacD resulted in a significant decrease of approximate fifty percent of Streptococcus suis serotype 2 invasion into bEND3.0 cells.,X Jiang 2022,2022,1 gene,Jiang-2022-Deletion of lacD gene affected stre,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20685,PHI:123409,UniProt,C0LTR9,GenBank,ACN32294,,,0919S911,tolC,,,,,,,562,Escherichia coli,,PPECC42,infection,rodents,10090,Mus musculus (related: house mouse),Kunming,,,heart; liver; spleen; lung; kidney; blood,tolerant colicin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36059454,PubMed,10.3389/fimmu.2022.929740,Front Immunol. 2022 Aug 18;13:929740,yulanflower@126.com,Loss of TolC drastically impaired the virulence of extraintestinal pathogenic Escherichia coli in mice.,J Hu 2022,2022,1 gene,Hu-2022-Effects of TolC on the pathogenicity o,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20686,PHI:123409,UniProt,C0LTR9,GenBank,ACN32294,,,0919S911,tolC,,,,,,,562,Escherichia coli,,PPECC42,infection,even-toed ungulates,9823,Sus scrofa (related: Pig),,,,porcine aortic endothelial cell,tolerant colicin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36059454,PubMed,10.3389/fimmu.2022.929740,Front Immunol. 2022 Aug 18;13:929740,yulanflower@126.com,"ΔTolC showed a substantial decrease in the porcine aortic vascular endothelial cell (PAVEC) adherence, invasion, and pro-inflammatory response, in contrast to that of the wild type. Tissue 'porcine aortic vascular endothelial cells (PAVEC)'.",J Hu 2022,2022,1 gene,Hu-2022-Effects of TolC on the pathogenicity o,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20687,PHI:123410,UniProt,I1S050,GenBank,CEF75405,,,PH-1,FgYCK1 (FGRRES_10066),chromosome 1,,,,,,5518,Fusarium graminearum,,Z-3643,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protein kinase domain-containing protein,,,,loss of pathogenicity,,,,,,reduced,reduced,reduced; defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36012372,PubMed,10.3390/ijms23169106,Int J Mol Sci. 2022 Aug 14;23(16):9106,jinrong@purdue.edu,"Deletion of FgYCK1 caused severe growth defects and loss of conidiation, fertility, and pathogenicity. Tissue 'flowering wheat heads'.",J Zhu 2022,2022,2 genes,Zhu-2022-Stage-Specific Genetic Interaction be,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20688,PHI:123410,UniProt,I1S050,GenBank,CEF75405,,,PH-1,FgYCK1 (FGRRES_10066),chromosome 1,,,,,,5518,Fusarium graminearum,,Z-3643,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,protein kinase domain-containing protein,,,,loss of pathogenicity,,,,,,reduced,reduced,reduced; defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36012372,PubMed,10.3390/ijms23169106,Int J Mol Sci. 2022 Aug 14;23(16):9106,jinrong@purdue.edu,"Deletion of FgYCK1 caused severe growth defects and loss of conidiation, fertility, and pathogenicity.",J Zhu 2022,2022,2 genes,Zhu-2022-Stage-Specific Genetic Interaction be,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20689,PHI:123410,UniProt,I1S050,GenBank,CEF75405,,,PH-1,FgYCK1 (FGRRES_10066),chromosome 1,,,,,PHI:123411,5518,Fusarium graminearum,,Z-3643,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,protein kinase domain-containing protein,,,,loss of pathogenicity,,,,,,reduced,reduced,reduced,,no,calcofluor white (CFW); Congo red,calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation; gene mutation: characterised,,,NN,36012372,PubMed,10.3390/ijms23169106,Int J Mol Sci. 2022 Aug 14;23(16):9106,jinrong@purdue.edu,"In infection assays with wheat heads, the Fgyck1/FgBNI4R699C mutants were nonpathogenic. Tissue 'flowering wheat heads'.",J Zhu 2022,2022,2 genes,Zhu-2022-Stage-Specific Genetic Interaction be,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20690,PHI:123411,UniProt,I1RST4,GenBank,CEF84806,,,PH-1,FgBNI4 (FGRRES_07218),chromosome 4,R699C,,,,PHI:123410,5518,Fusarium graminearum,,Z-3643,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,scaffold protein,,,,loss of pathogenicity,,,,,,reduced,reduced,reduced,,no,calcofluor white (CFW); Congo red,calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation; gene mutation: characterised,,,NN,36012372,PubMed,10.3390/ijms23169106,Int J Mol Sci. 2022 Aug 14;23(16):9106,jinrong@purdue.edu,"In infection assays with wheat heads, the Fgyck1/FgBNI4R699C mutants were nonpathogenic. Tissue 'flowering wheat heads'.",J Zhu 2022,2022,2 genes,Zhu-2022-Stage-Specific Genetic Interaction be,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20691,PHI:123419,UniProt,P25084,GenBank,AAA25874,,,PAO1,lasR,,,,,,PHI:2,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,transcriptional activator protein LasR,,,IL-17A pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36033859,PubMed,10.3389/fmicb.2022.948646,Front Microbiol. 2022 Aug 10;13:948646,tanlp0825@hotmail.com,AI-2 could activate the IL-17A pathway via the QS system during P.aeruginosa lung infections,H Li 2022,2022,2 genes,Li-2022-Autoinducer-2 promotes Pseudomonas aer,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20692,PHI:123420,UniProt,P54292,GenBank,AAC44036,,,PAO1,rhlR,chromosome 1,,,,,PHI:1,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,HTH-type quorum-sensing regulator RhlR,,,IL-17A pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36033859,PubMed,10.3389/fmicb.2022.948646,Front Microbiol. 2022 Aug 10;13:948646,tanlp0825@hotmail.com,AI-2 could activate the IL-17A pathway via the QS system during P.aeruginosa lung infections,H Li 2022,2022,2 genes,Li-2022-Autoinducer-2 promotes Pseudomonas aer,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20693,PHI:123421,UniProt,G4N4P0,GenBank,EHA52855,,,70-15,CRZ1 (MGG_05133),chromosome 3,,,,,,318829,Magnaporthe oryzae,,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,calcineurin responsive transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,NN,36035704,PubMed,10.3389/fpls.2022.959641,Front Plant Sci. 2022 Aug 11;13:959641,ralph_dean@ncsu.edu,"HIGS vectors were transformed into rice calli through Agrobacterium-mediated transformation and T0, T1 and T2 generations of transgenic rice plants were generated",M Wang 2022,2022,6 genes,Wang-2022-Host induced gene silencing of Magna,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20694,PHI:123422,UniProt,G4MS02,GenBank,EHA56671,,,70-15,PMC1 (MGG_02487),chromosome 1,,,,,,318829,Magnaporthe oryzae,,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,calcium-transporting ATPase 2 (vacuolar Ca2C-ATPase),,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,NN,36035704,PubMed,10.3389/fpls.2022.959641,Front Plant Sci. 2022 Aug 11;13:959641,ralph_dean@ncsu.edu,"HIGS vectors were transformed into rice calli through Agrobacterium-mediated transformation and T0, T1 and T2 generations of transgenic rice plants were generated",M Wang 2022,2022,6 genes,Wang-2022-Host induced gene silencing of Magna,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20695,PHI:123423,UniProt,O13315,GenBank,AAB65426,,,70-15,MAGB (MGG_00365),,,,,,,318829,Magnaporthe oryzae,,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,guanine nucleotide-binding protein subunit alpha,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,NN,36035704,PubMed,10.3389/fpls.2022.959641,Front Plant Sci. 2022 Aug 11;13:959641,ralph_dean@ncsu.edu,"HIGS vectors were transformed into rice calli through Agrobacterium-mediated transformation and T0, T1 and T2 generations of transgenic rice plants were generated",M Wang 2022,2022,6 genes,Wang-2022-Host induced gene silencing of Magna,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20696,PHI:123424,UniProt,G4MKQ2,GenBank,EHA56742,,,70-15,LHS1 (MGG_06648),chromosome 1,,,,,,318829,Magnaporthe oryzae,,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,"ER chaperon, essential for translocation of secreted protein across ER membrane",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,NN,36035704,PubMed,10.3389/fpls.2022.959641,Front Plant Sci. 2022 Aug 11;13:959641,ralph_dean@ncsu.edu,"HIGS vectors were transformed into rice calli through Agrobacterium-mediated transformation and T0, T1 and T2 generations of transgenic rice plants were generated",M Wang 2022,2022,6 genes,Wang-2022-Host induced gene silencing of Magna,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20697,PHI:123425,UniProt,G4MRP8,GenBank,EHA58263,,,70-15,CYP51A (MGG_04628),chromosome 1,,,,,,318829,Magnaporthe oryzae,,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,"cytochrome P450 51, essential for ergosterol biosynthesis, membrane integrity",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,NN,36035704,PubMed,10.3389/fpls.2022.959641,Front Plant Sci. 2022 Aug 11;13:959641,ralph_dean@ncsu.edu,"HIGS vectors were transformed into rice calli through Agrobacterium-mediated transformation and T0, T1 and T2 generations of transgenic rice plants were generated",M Wang 2022,2022,6 genes,Wang-2022-Host induced gene silencing of Magna,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20698,PHI:123426,UniProt,G4MZG5,GenBank,EHA53720,,,70-15,CYP51B (MGG_04432),chromosome 2,,,,,,318829,Magnaporthe oryzae,,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),subsp. japonica cv. Nipponbare,,,leaf,"cytochrome P450 51, essential for ergosterol biosynthesis, membrane integrity",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing; other evidence: transgenic plants,,,NN,36035704,PubMed,10.3389/fpls.2022.959641,Front Plant Sci. 2022 Aug 11;13:959641,ralph_dean@ncsu.edu,"HIGS vectors were transformed into rice calli through Agrobacterium-mediated transformation and T0, T1 and T2 generations of transgenic rice plants were generated",M Wang 2022,2022,6 genes,Wang-2022-Host induced gene silencing of Magna,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20699,PHI:123427,UniProt,Q4X1S9,GenBank,EAL93186,,,Af293,clcA,chromosome 2,,,,,,746128,Aspergillus fumigatus,330879,Af293,aspergillosis,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,"voltage-gated chloride channel (ClcA), putative",,,,unaffected pathogenicity,,,,,,defective,,reduced; defective,,no,micafungin; amphotericin B; 5-flucytosine; fluconazole; itraconazole; voriconazole; miconazole,micafungin: CHEBI:600520; amphotericin B: CHEBI:2682; 5-flucytosine: CHEBI:5100; fluconazole: CHEBI:46081; itraconazole: CHEBI:6076; voriconazole: CHEBI:10023; miconazole: CHEBI:6923,,,,,gene deletion: full; gene complementation,,,NN,35972528,PubMed,10.1007/s00294-022-01250-2,Curr Genet. 2022 Aug 16,hiroki.takahashi@chiba-u.jp,"ΔclcA strain exhibited defective growth on minimal medium, PDA and copper-repleted medium, and defective conidiogenesis and conidial pigmentation. We found that clcA was required for the expressions of genes involved in conidiogenesis, conidial pigmentation, and transporters cdr1B and mfsB related to azole resistance. clcA was dispensable for the virulence in silkworm infection model.",Y Kusuya 2022,2022,1 gene,Kusuya-2022-A novel Zn(2)-Cys(6) transcription,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20700,PHI:123428,,no data found,GenBank,UTS53364,,,SH112,vemL (OL347638),,,,,,,670,Vibrio parahaemolyticus,,SH112,vibriosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,membrane fusion protein,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36016795,PubMed,10.3389/fmicb.2022.976334,Front Microbiol. 2022 Aug 9;13:976334,jiangweijw99@163.com,"Reduced biofilm formation due to decreased production of biofilm exopolysaccharide upon vmeL deletion. In addition, the deletion of vmeL abolished surface swarming and swimming motility of V.parahaemolyticus.",P X Liu 2022,2022,1 gene,Liu-2022-Biological and transcriptional studie,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20701,PHI:123428,,no data found,GenBank,UTS53364,,,SH112,vemL (OL347638),,,,,,,670,Vibrio parahaemolyticus,,SH112,vibriosis,rodents,10090,Mus musculus (related: house mouse),,,,,membrane fusion protein,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36016795,PubMed,10.3389/fmicb.2022.976334,Front Microbiol. 2022 Aug 9;13:976334,jiangweijw99@163.com,"Reduced biofilm formation due to decreased production of biofilm exopolysaccharide upon vmeL deletion. In addition, the deletion of vmeL abolished surface swarming and swimming motility of V.parahaemolyticus.",P X Liu 2022,2022,1 gene,Liu-2022-Biological and transcriptional studie,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20702,PHI:123429,UniProt,Q8P880,GenBank,AAM41641,,,ATCC 33913,saxB (XCC2363),,,,,,PHI:123430,339,Xanthomonas campestris,,pv. campestris strain Xc1,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,isochorismatase domain-containing protein,,,,reduced virulence,,,,,reduced lesions,,,reduced,,no,sulforaphane; H202,sulforaphane: CHEBI:47807; H2O2: CHEBI:16240,,,,,gene mutation,,,NN,35942507,PubMed,10.1111/mpp.13245,Mol Plant Pathol. 2022 Oct;23(10):1508-1523,fqliu20011@sina.com,"secondary metabolite sulforaphane (SFN) in crucifers inhibits the growth, virulence, and ability of Xanthomonas species to adapt to oxidative stress, which is essential for the successful infection of host plants by phytopathogens",B Wang 2022,2022,2 genes,"Wang-2022-Sulforaphane, a secondary metabolite",BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20703,PHI:123430,UniProt,Q8PAN9,GenBank,AAM40737,,,ATCC 33913,saxF (XCC1440),,,,,,PHI:123429,339,Xanthomonas campestris,,pv. campestris strain Xc1,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,efflux pump membrane transporter,,,,reduced virulence,,,,,reduced lesions,,,reduced,,no,sulforaphane; H202,sulforaphane: CHEBI:47807; H2O2: CHEBI:16240,,,,,gene mutation,,,NN,35942507,PubMed,10.1111/mpp.13245,Mol Plant Pathol. 2022 Oct;23(10):1508-1523,fqliu20011@sina.com,"secondary metabolite sulforaphane (SFN) in crucifers inhibits the growth, virulence, and ability of Xanthomonas species to adapt to oxidative stress, which is essential for the successful infection of host plants by phytopathogens",B Wang 2022,2022,2 genes,"Wang-2022-Sulforaphane, a secondary metabolite",BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20704,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein A,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,deficiency of OmpA in Salmonella increased its phagocytosis by RAW264.7 and activated U937 cells,A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20705,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),U-937 cell line,,,macrophage,outer membrane protein A,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,deficiency of OmpA in Salmonella increased its phagocytosis by RAW264.7 and activated U937 cells,A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20706,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,CACO-2 cell,outer membrane protein A,,,,increased virulence (hypervirulence),,,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"Compared to the wild-type bacteria, STMΔompA exhibited an attenuated invasion of epithelial cells",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20707,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,outer membrane protein A,,,,increased virulence (hypervirulence),,,yes,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"Compared to the wild-type bacteria, STMΔompA exhibited an attenuated invasion of epithelial cells",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20708,PHI:123432,UniProt,A0A8E6N242,GenBank,QVP84306,,,SGSC 2189,sifA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,SPI-2 type III secretion system effector SifA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"compared to STM (WT), the higher and indistinguishable level of intracellular NO induced by STM ΔompA, ΔsifA, ΔompAΔsifA, ΔssaV, and ΔompAΔssaV suggested that increased NO response of macrophages upon STM ΔompA infection depends on the attenuated expression of SPI-2 genes",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20709,PHI:123433,UniProt,A0A8E6N7P7,GenBank,QVP84130,,,SGSC 2189,ssaV,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,SPI-2 type III secretion system apparatus protein SsaV,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"compared to STM (WT), the higher and indistinguishable level of intracellular NO induced by STM ΔompA, ΔsifA, ΔompAΔsifA, ΔssaV, and ΔompAΔssaV suggested that increased NO response of macrophages upon STM ΔompA infection depends on the attenuated expression of SPI-2 genes",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20710,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,PHI:123432,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"compared to STM (WT), the higher and indistinguishable level of intracellular NO induced by STM ΔompA, ΔsifA, ΔompAΔsifA, ΔssaV, and ΔompAΔssaV suggested that increased NO response of macrophages upon STM ΔompA infection depends on the attenuated expression of SPI-2 genes",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20711,PHI:123432,UniProt,A0A8E6N242,GenBank,QVP84306,,,SGSC 2189,sifA,,,,,,PHI:123431,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,SPI-2 type III secretion system effector SifA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"compared to STM (WT), the higher and indistinguishable level of intracellular NO induced by STM ΔompA, ΔsifA, ΔompAΔsifA, ΔssaV, and ΔompAΔssaV suggested that increased NO response of macrophages upon STM ΔompA infection depends on the attenuated expression of SPI-2 genes",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20712,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,PHI:123433,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"compared to STM (WT), the higher and indistinguishable level of intracellular NO induced by STM ΔompA, ΔsifA, ΔompAΔsifA, ΔssaV, and ΔompAΔssaV suggested that increased NO response of macrophages upon STM ΔompA infection depends on the attenuated expression of SPI-2 genes",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20713,PHI:123433,UniProt,A0A8E6N7P7,GenBank,QVP84130,,,SGSC 2189,ssaV,,,,,,PHI:123431,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,SPI-2 type III secretion system apparatus protein SsaV,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"compared to STM (WT), the higher and indistinguishable level of intracellular NO induced by STM ΔompA, ΔsifA, ΔompAΔsifA, ΔssaV, and ΔompAΔssaV suggested that increased NO response of macrophages upon STM ΔompA infection depends on the attenuated expression of SPI-2 genes",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20714,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein A,,,,unaffected pathogenicity,,,,,,,,,,no,1400W (dihydrochloride),1400W (dihydrochloride): CHEBI:90721,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,In presence of iNOS inhibitor,A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20715,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,In presence of iNOS activator IFN-gamma,A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20716,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"The reduced CFU burden of ompA mutant compared to the wild-type Salmonella in the liver, spleen, and MLN of C57BL/6 mice strongly supports the role of OmpA in bacterial pathogenesis",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20717,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node,outer membrane protein A,,,,increased virulence (hypervirulence),,,,,,,,,,no,aminoguanidine hydrochloride,aminoguanidine hydrochloride CAS no.: CAS:1937-19-5,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,Restoration of higher STM ΔompA burden in AGH treated and iNOS-/- C57BL/6 mice concomitantly confirmed the role of OmpA in protecting Salmonella from in vivo nitrosative stress,A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20718,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"The reduced CFU burden of ompA mutant compared to the wild-type Salmonella in the liver, spleen, and MLN of C57BL/6 mice strongly supports the role of OmpA in bacterial pathogenesis",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20719,PHI:123434,UniProt,A0A8E6JBZ7,GenBank,QVP84020,,,SGSC 2189,ompC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,porin OmpC,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"A decreased recruitment of nitrotyrosine on STM ΔompC, ΔompD, and ΔompF in comparison with STM ΔompA in RAW264.7 macrophages confirmed the presence of intact SCV membrane around them. . In addition, unlike STM ΔompA, the ability of STM ΔompC, ΔompD, and ΔompF to withstand the bactericidal effect of acidified nitrite suggested the dispensability of these larger porins in protecting Salmonella from nitrosative stress",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20720,PHI:123435,UniProt,A0A8E6NBK9,GenBank,QVP88165,,,SGSC 2189,ompD,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,porin OmpD,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"A decreased recruitment of nitrotyrosine on STM ΔompC, ΔompD, and ΔompF in comparison with STM ΔompA in RAW264.7 macrophages confirmed the presence of intact SCV membrane around them. . In addition, unlike STM ΔompA, the ability of STM ΔompC, ΔompD, and ΔompF to withstand the bactericidal effect of acidified nitrite suggested the dispensability of these larger porins in protecting Salmonella from nitrosative stress",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20721,PHI:123436,UniProt,A0A8E6N088,GenBank,QVP84518,,,SGSC 2189,ompF,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,porin OmpF,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"A decreased recruitment of nitrotyrosine on STM ΔompC, ΔompD, and ΔompF in comparison with STM ΔompA in RAW264.7 macrophages confirmed the presence of intact SCV membrane around them. . In addition, unlike STM ΔompA, the ability of STM ΔompC, ΔompD, and ΔompF to withstand the bactericidal effect of acidified nitrite suggested the dispensability of these larger porins in protecting Salmonella from nitrosative stress",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20722,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,PHI:123434,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"STM ΔompC, ΔompD, and ΔompF are more efficient in restricting the entry of nitrite compared to STM ΔompA",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20723,PHI:123434,UniProt,A0A8E6JBZ7,GenBank,QVP84020,,,SGSC 2189,ompC,,,,,,PHI:123431,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,porin OmpC,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"STM ΔompC, ΔompD, and ΔompF are more efficient in restricting the entry of nitrite compared to STM ΔompA",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20724,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,PHI:123435,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"STM ΔompC, ΔompD, and ΔompF are more efficient in restricting the entry of nitrite compared to STM ΔompA",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20725,PHI:123435,UniProt,A0A8E6NBK9,GenBank,QVP88165,,,SGSC 2189,ompD,,,,,,PHI:123431,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,porin OmpD,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"STM ΔompC, ΔompD, and ΔompF are more efficient in restricting the entry of nitrite compared to STM ΔompA",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20726,PHI:123431,UniProt,A0A0F6AZN3,GenBank,ACY87707,,,14028S,ompA,,,,,,PHI:123436,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,outer membrane protein A,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"STM ΔompC, ΔompD, and ΔompF are more efficient in restricting the entry of nitrite compared to STM ΔompA",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20727,PHI:123436,UniProt,A0A8E6N088,GenBank,QVP84518,,,SGSC 2189,ompF,,,,,,PHI:123431,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,porin OmpF,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35969640,PubMed,10.1371/journal.ppat.1010708,PLoS Pathog. 2022 Aug 15;18(8):e1010708,dipa@iisc.ac.in,"STM ΔompC, ΔompD, and ΔompF are more efficient in restricting the entry of nitrite compared to STM ΔompA",A R Chowdhury 2022,2022,6 genes,Roy Chowdhury-2022-Salmonella Typhimurium oute,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20728,PHI:123437,,no data found,,,,,,hxuI,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,extracytoplasmic function (ECF) sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35044199,PubMed,10.1128/spectrum.01620-21,Microbiol Spectr. 2022 Feb 23;10(1):e0162021,baifang1122@nankai.edu.cn.,"Under anaerobic condition, the growth rate of the hxuI deletion mutant was slower than that of the parent strain PAO1, while no growth defect was observed under aerobic conditions",Z Cai 2022,2022,1 gene,Cai-2022-ECF Sigma Factor HxuI Is Critical for,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20729,PHI:123438,UniProt,O97336,GenBank,CAB39133,,,,PTP7 (PF3D7_0301700),,,,,,,5833,Plasmodium falciparum,,CS2,malaria,primates,9606,Homo sapiens (related: human),,,,erythrocyte,EMP1 trafficking protein-7,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35930605,PubMed,10.1371/journal.ppat.1009882,PLoS Pathog. 2022 Aug 5;18(8):e1009882,matthew.dixon@unimelb.edu.au,"Characteristic knob structures (76 ±11 nm diameter) are observedon the wildtype CS2-infected RBCs, however ΔPTP7-infected RBCs exhibited fewer, largerknobs (108 ±20 nm diameter)",O M S Carmo 2022,2022,1 gene,Carmo-2022-Deletion of the Plasmodium falcipar,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20730,PHI:123438,UniProt,O97336,GenBank,CAB39133,,,,PTP7 (PF3D7_0301700),,"amino acids 265-317 deleted, leaving the transmembrane domain and four amino acids as a linker",,,,,5833,Plasmodium falciparum,,CS2,malaria,primates,9606,Homo sapiens (related: human),,,,erythrocyte,EMP1 trafficking protein-7,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: partial,,,NN,35930605,PubMed,10.1371/journal.ppat.1009882,PLoS Pathog. 2022 Aug 5;18(8):e1009882,matthew.dixon@unimelb.edu.au,"Complete loss of EMP1 from the surface is observed in the PTP7 Δ265-317 infected RBCs, while faint trypsinized EMP1 bands are observed in both PTP7 Δ278-310 and PTP7 Δ300-317 parasites",O M S Carmo 2022,2022,1 gene,Carmo-2022-Deletion of the Plasmodium falcipar,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20731,PHI:123438,UniProt,O97336,GenBank,CAB39133,,,,PTP7 (PF3D7_0301700),,"internal deletion removing the asparagine repeats (Δ278-310), leaving the C-terminal poly basic motif 'KKSKKN'",,,,,5833,Plasmodium falciparum,,CS2,malaria,primates,9606,Homo sapiens (related: human),,,,erythrocyte,EMP1 trafficking protein-7,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,NN,35930605,PubMed,10.1371/journal.ppat.1009882,PLoS Pathog. 2022 Aug 5;18(8):e1009882,matthew.dixon@unimelb.edu.au,"Complete loss of EMP1 from the surface is observed in the PTP7 Δ265-317 infected RBCs, while faint trypsinized EMP1 bands are observed in both PTP7 Δ278-310 and PTP7 Δ300-317 parasites",O M S Carmo 2022,2022,1 gene,Carmo-2022-Deletion of the Plasmodium falcipar,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20732,PHI:123438,UniProt,O97336,GenBank,CAB39133,,,,PTP7 (PF3D7_0301700),,truncation that removes the poly basic motif (Δ300-317),,,,,5833,Plasmodium falciparum,,CS2,malaria,primates,9606,Homo sapiens (related: human),,,,erythrocyte,EMP1 trafficking protein-7,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: partial,,,NN,35930605,PubMed,10.1371/journal.ppat.1009882,PLoS Pathog. 2022 Aug 5;18(8):e1009882,matthew.dixon@unimelb.edu.au,"Complete loss of EMP1 from the surface is observed in the PTP7 Δ265-317 infected RBCs, while faint trypsinized EMP1 bands are observed in both PTP7 Δ278-310 and PTP7 Δ300-317 parasites",O M S Carmo 2022,2022,1 gene,Carmo-2022-Deletion of the Plasmodium falcipar,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20733,PHI:123439,UniProt,A0A0K0GI99,GenBank,ACD57942,,,PXO99A,minC (PXO_04463),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,probable septum site-determining protein MinC,,,HrpG-HrpX regulatory pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20734,PHI:123440,UniProt,A0A0K0GI74,GenBank,ACD57941,,,PXO99A,minD (PXO_04464),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,septum site-determining protein MinD,,,HrpG-HrpX regulatory pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20735,PHI:123439,UniProt,A0A0K0GI99,GenBank,ACD57942,,,PXO99A,minC (PXO_04463),,,,,,PHI:123440; PHI:123441,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,probable septum site-determining protein MinC,,,HrpG-HrpX regulatory pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20736,PHI:123440,UniProt,A0A0K0GI74,GenBank,ACD57941,,,PXO99A,minD (PXO_04464),,,,,,PHI:123439; PHI:123441,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,septum site-determining protein MinD,,,HrpG-HrpX regulatory pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20737,PHI:123441,UniProt,B2SRH1,GenBank,ACD57940,,,PXO99A,minE (PXO_04465),,,,,,PHI:123439; PHI:123440,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,cell division topological specificity factor,,,HrpG-HrpX regulatory pathway,reduced virulence,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20738,PHI:123439,UniProt,A0A0K0GI99,GenBank,ACD57942,,,PXO99A,minC (PXO_04463),,"Transposon mutant 8-24 with up-regulated expression of hrpF and hrpB1, using a Tn5 transposon mutagenesis, in which the transposon was inserted into the Xoo PXO99A minC",,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,probable septum site-determining protein MinC,,,HrpG-HrpX regulatory pathway,reduced virulence,,,,,decreased lesion length,,,aberrant,,no,,,,,,,gene disruption,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20739,PHI:123439,UniProt,A0A0K0GI99,GenBank,ACD57942,,,PXO99A,minC (PXO_04463),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,probable septum site-determining protein MinC,,,HrpG-HrpX regulatory pathway,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20740,PHI:123440,UniProt,A0A0K0GI74,GenBank,ACD57941,,,PXO99A,minD (PXO_04464),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,septum site-determining protein MinD,,,HrpG-HrpX regulatory pathway,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20741,PHI:123439,UniProt,A0A0K0GI99,GenBank,ACD57942,,,PXO99A,minC (PXO_04463),,,,,,PHI:123440; PHI:123441,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,probable septum site-determining protein MinC,,,HrpG-HrpX regulatory pathway,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20742,PHI:123440,UniProt,A0A0K0GI74,GenBank,ACD57941,,,PXO99A,minD (PXO_04464),,,,,,PHI:123439; PHI:123441,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,septum site-determining protein MinD,,,HrpG-HrpX regulatory pathway,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20743,PHI:123441,UniProt,B2SRH1,GenBank,ACD57940,,,PXO99A,minE (PXO_04465),,,,,,PHI:123439; PHI:123440,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,cell division topological specificity factor,,,HrpG-HrpX regulatory pathway,unaffected pathogenicity,,,,,,,,aberrant,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20744,PHI:123439,UniProt,A0A0K0GI99,GenBank,ACD57942,,,PXO99A,minC (PXO_04463),,"Transposon mutant 8-24 with up-regulated expression of hrpF and hrpB1, using a Tn5 transposon mutagenesis, in which the transposon was inserted into the Xoo PXO99A minC",,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99,bacterial leaf blight,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,probable septum site-determining protein MinC,,,HrpG-HrpX regulatory pathway,unaffected pathogenicity,,,,,decreased lesion length,,,aberrant,,no,,,,,,,gene disruption,,,NN,36013967,PubMed,10.3390/microorganisms10081549,Microorganisms. 2022 Jul 31;10(8):1549,yichao.yan@sjtu.edu.cn,"Did not exhibit significant swimming motility, produced more significant biofilm",Y Yan 2022,2022,3 genes,Yan-2022-The MinCDE Cell Division System Parti,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20745,PHI:123442,UniProt,B4EXB5,GenBank,CAR44976,,,HI4320,yntA,,,,,,,584,Proteus mirabilis,529507,HI4320,catheter-associated urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urinary bladder; kidney; spleen,"putative nickel/di-oligopepetide ABC transporter, substrate-binding protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,32255226,PubMed,10.1111/mmi.14505,Mol Microbiol. 2020 Aug;114(2):185-199,chelsiea@buffalo.edu,yntA mutant exhibited a severe colonization defect in the majority of mice and was significantly outcompeted by wild-type P. mirabilis in all organs,A L Brauer 2020,2020,3 genes,Brauer-2020-Ynt is the primary nickel import s,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20746,PHI:123443,UniProt,B4EZP9,GenBank,CAR45801,,,HI4320,nikA,,,,,,,584,Proteus mirabilis,529507,HI4320,catheter-associated urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urinary bladder; kidney; spleen,ABC transporter. substrate-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,32255226,PubMed,10.1111/mmi.14505,Mol Microbiol. 2020 Aug;114(2):185-199,chelsiea@buffalo.edu,nikA mutant colonized the urinary tract to a similar level as wild-type P. mirabilis in the majority of mice and was only significantly outcompeted by wild type in the spleen,A L Brauer 2020,2020,3 genes,Brauer-2020-Ynt is the primary nickel import s,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20747,PHI:123442,UniProt,B4EXB5,GenBank,CAR44976,,,HI4320,yntA,,,,,,PHI:123443,584,Proteus mirabilis,529507,HI4320,catheter-associated urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urinary bladder; kidney; spleen,"putative nickel/di-oligopepetide ABC transporter, substrate-binding protein",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,32255226,PubMed,10.1111/mmi.14505,Mol Microbiol. 2020 Aug;114(2):185-199,chelsiea@buffalo.edu,"double mutant was recovered at or near the limit of detection in all mice and was signifi-cantlyoutcompeted by wild-type P. mirabilis in the urine, bladder and kidneys",A L Brauer 2020,2020,3 genes,Brauer-2020-Ynt is the primary nickel import s,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20748,PHI:123443,UniProt,B4EZP9,GenBank,CAR45801,,,HI4320,nikA,,,,,,PHI:123442,584,Proteus mirabilis,529507,HI4320,catheter-associated urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urinary bladder; kidney; spleen,ABC transporter. substrate-binding protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,32255226,PubMed,10.1111/mmi.14505,Mol Microbiol. 2020 Aug;114(2):185-199,chelsiea@buffalo.edu,"double mutant was recovered at or near the limit of detection in all mice and was signifi-cantlyoutcompeted by wild-type P. mirabilis in the urine, bladder and kidneys",A L Brauer 2020,2020,3 genes,Brauer-2020-Ynt is the primary nickel import s,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20749,PHI:123444,UniProt,P17091,GenBank,CAR47188,,,HI4320,ureF,,,,,,PHI:123442,584,Proteus mirabilis,529507,HI4320,catheter-associated urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urinary bladder; kidney; spleen,urease accessory protein UreF,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32255226,PubMed,10.1111/mmi.14505,Mol Microbiol. 2020 Aug;114(2):185-199,chelsiea@buffalo.edu,"Despite having such pronounced fitness defects during co-challenge with wild-type P. mirabilis, the yntA/ureF double mutant and the nikA/ureF double mutant both colonized the catheterized urinary tract to a similar level as the ureF mutant",A L Brauer 2020,2020,3 genes,Brauer-2020-Ynt is the primary nickel import s,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20750,PHI:123442,UniProt,B4EXB5,GenBank,CAR44976,,,HI4320,yntA,,,,,,PHI:123444,584,Proteus mirabilis,529507,HI4320,catheter-associated urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urinary bladder; kidney; spleen,"putative nickel/di-oligopepetide ABC transporter, substrate-binding protein",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32255226,PubMed,10.1111/mmi.14505,Mol Microbiol. 2020 Aug;114(2):185-199,chelsiea@buffalo.edu,"Despite having such pronounced fitness defects during co-challenge with wild-type P. mirabilis, the yntA/ureF double mutant and the nikA/ureF double mutant both colonized the catheterized urinary tract to a similar level as the ureF mutant",A L Brauer 2020,2020,3 genes,Brauer-2020-Ynt is the primary nickel import s,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20751,PHI:123444,UniProt,P17091,GenBank,CAR47188,,,HI4320,ureF,,,,,,PHI:123443,584,Proteus mirabilis,529507,HI4320,catheter-associated urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urinary bladder; kidney; spleen,urease accessory protein UreF,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32255226,PubMed,10.1111/mmi.14505,Mol Microbiol. 2020 Aug;114(2):185-199,chelsiea@buffalo.edu,"Despite having such pronounced fitness defects during co-challenge with wild-type P. mirabilis, the yntA/ureF double mutant and the nikA/ureF double mutant both colonized the catheterized urinary tract to a similar level as the ureF mutant",A L Brauer 2020,2020,3 genes,Brauer-2020-Ynt is the primary nickel import s,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20752,PHI:123443,UniProt,B4EZP9,GenBank,CAR45801,,,HI4320,nikA,,,,,,PHI:123444,584,Proteus mirabilis,529507,HI4320,catheter-associated urinary tract infection,rodents,10090,Mus musculus (related: house mouse),CBA/J,,,urinary bladder; kidney; spleen,ABC transporter. substrate-binding protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32255226,PubMed,10.1111/mmi.14505,Mol Microbiol. 2020 Aug;114(2):185-199,chelsiea@buffalo.edu,"Despite having such pronounced fitness defects during co-challenge with wild-type P. mirabilis, the yntA/ureF double mutant and the nikA/ureF double mutant both colonized the catheterized urinary tract to a similar level as the ureF mutant",A L Brauer 2020,2020,3 genes,Brauer-2020-Ynt is the primary nickel import s,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20753,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,AvrBs3Δ2 reporter fusion containing HpaA deleted in amino acids 2-70,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,"When bacteria were infiltrated into leaves of AvrBs3-responsive pepper plants, HpaA1-70-AvrBs3Δ2 but not HpaAΔ2-70-AvrBs3Δ2 induced a visible HR, suggesting that the N-terminal 70 amino acids are sufficient and essential for translocation of HpaA (Strain 85* contains a constitutively active version of the key regulator HrpG)",S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20754,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,expression constructs containing the N-terminal 50 (lacking the TrM) of HpaA as fusion partners of AvrBs3Δ2 (HpaA1-50-AvrBs3Δ2),,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,HpaA1-50-AvrBs3Δ2 and HpaA1-60-AvrBs3Δ2 were stably synthesized but did not elicit a visible HR in AvrBs3-responsive pepper plants (Strain 85* contains a constitutively active version of the key regulator HrpG),S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20755,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,expression constructs containing the N-terminal 60 (including the Pro/Arg-rich sequence) amino acids of HpaA as fusion partners of AvrBs3Δ2 (HpaA1-60-AvrBs3Δ2),,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,HpaA1-50-AvrBs3Δ2 and HpaA1-60-AvrBs3Δ2 were stably synthesized but did not elicit a visible HR in AvrBs3-responsive pepper plants (Strain 85* contains a constitutively active version of the key regulator HrpG),S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20756,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,AvrBs3Δ2 reporter fusion containing HpaA deleted in amino acids 2-70,,,,PHI:123446,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20757,PHI:123446,UniProt,A0A7W7P8L9,GenBank,MBB4872513,,,CFBP 7921,hpaB,,,,,,PHI:123445,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20758,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,expression constructs containing the N-terminal 50 (lacking the TrM) of HpaA as fusion partners of AvrBs3Δ2 (HpaA1-50-AvrBs3Δ2),,,,PHI:123446,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,"hpaB deletion mutant strain 85*ΔhpaB, HpaA1-50-AvrBs3Δ2 induced the AvrBs3-specific HR, indicating that the N-terminal 50 amino acids of HpaA contain a minimal translocation signal which is recognized in the absence of HpaB but not in the wild-type strain (Strain 85* contains a constitutively active version of the key regulator HrpG)",S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20759,PHI:123446,UniProt,A0A7W7P8L9,GenBank,MBB4872513,,,CFBP 7921,hpaB,,,,,,PHI:123445,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,"hpaB deletion mutant strain 85*ΔhpaB, HpaA1-50-AvrBs3Δ2 induced the AvrBs3-specific HR, indicating that the N-terminal 50 amino acids of HpaA contain a minimal translocation signal which is recognized in the absence of HpaB but not in the wild-type strain (Strain 85* contains a constitutively active version of the key regulator HrpG)",S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20760,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,expression constructs containing the N-terminal 50 (lacking the TrM) of HpaA as fusion partners of AvrBs3Δ2 (HpaA1-50-AvrBs3Δ2),,,,PHI:123446,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20761,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,expression constructs containing the N-terminal 60 (including the Pro/Arg-rich sequence) amino acids of HpaA as fusion partners of AvrBs3Δ2 (HpaA1-60-AvrBs3Δ2),,,,PHI:123445,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20762,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,point mutations leading to the exchange of amino acids 54-PRRRRRG-60 to 54-PAAAAAG-60 (TrMmut),,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20763,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,point mutations leading to the exchange of amino acids 54-PRRRRRG-60 to 54-PAAAAAG-60 (TrMmut),,,,PHI:123446,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20764,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20765,PHI:123446,UniProt,A0A7W7P8L9,GenBank,MBB4872513,,,CFBP 7921,hpaB,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 30R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20766,PHI:123445,UniProt,Q9WWF9,GenBank,AAD21323,,,75-3,hpaA,,,,,,PHI:123446,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20767,PHI:123446,UniProt,A0A7W7P8L9,GenBank,MBB4872513,,,CFBP 7921,hpaB,,,,,,PHI:123445,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20768,PHI:123447,UniProt,Q3BYJ7,GenBank,CAJ22066,,,85-10,hrcC,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20769,PHI:123448,UniProt,Q3BYK8,GenBank,CAJ22055,,,85-10,hpaC,,,,,,,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20770,PHI:123448,UniProt,Q3BYK8,GenBank,CAJ22055,,,85-10,hpaC,,,,,,PHI:123449,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20771,PHI:123449,UniProt,Q3BYK6,GenBank,CAJ22057,,,85-10,hrcU,,genomic point mutation (Y318D amino acid exchange,,,,PHI:123448,339,Xanthomonas campestris,316273,pv. vesicatoria strain 85-10,bacterial leaf spot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,35968103,PubMed,10.3389/fpls.2022.955776,Front Plant Sci. 2022 Jul 28;13:955776,daniela.buettner@genetik.uni-halle.de,Strain 85* containing a constitutively active version of the key regulator HrpG is used,S Drehkopf 2022,2022,5 genes,Drehkopf-2022-Recognition of a translocation m,BATCH_115A,2022-09-01,MC,,,,,,,,,,,,,
,,Record 20772,PHI:123450,UniProt,Q6FNU3,GenBank,CAG61052,,,CBS 138,CgSNF3 (CAGL0J09020g),chromosome 3,,,,,,5478,Candida glabrata,284593,CBS 138,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; kidney; liver,high-affinity glucose sensor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35051415,PubMed,10.1016/j.jbc.2022.101593,J Biol Chem. 2022 Feb;298(2):101593,rkaur@cdfd.org.in,"1000-fold lower fungal colony-forming units from kidneys of Cgsnf3Δ-infected BALB/c mice were recovered, compared with wt-infected BALB/c mice.",F Askari 2022,2022,1 gene,Askari-2022-The yapsin family of aspartyl prot,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20773,PHI:123451,UniProt,Q4WXL2,GenBank,EAL92591,,,Af293,AfgapA (Afu3G09900),chromosome 3,,,,,,746128,Aspergillus fumigatus,1266464,AfS35,pulmonary aspergillosis,moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,GTPase activating protein,,,,increased virulence (hypervirulence),,,,,,reduced; defective,,,,no,,,,,,,gene deletion: full; gene complementation; gene mutation: characterised,,,NN,35941233,PubMed,10.1007/s00294-022-01249-9,Curr Genet. 2022 Aug 8,hiroki.takahashi@chiba-u.jp,Afs35-G20 having nonsense mutation Tyr757Ter showed a slightly higher virulence than Afs35 and ΔAfgapA exhibited hypervirulence as assessed by a Galleria mellonella model.,C Bian 2022,2022,1 gene,Bian-2022-Dysfunction of Ras-GAP protein Afgap,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20774,PHI:123452,UniProt,Q8Y719,GenBank,CAC99585,,,EGD-e,lmo1507,,pieR* E81V,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl,NaCl: CHEBI:26710,,,,,gene mutation: characterised,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,There was no difference between wild type and the lmo1507 mutant E81V with respect bacterial burden in liver and spleen of infected mice.,L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20775,PHI:123452,UniProt,Q8Y719,GenBank,CAC99585,,,EGD-e,lmo1507,,Deletion of pieRS (genes lmo1507 and lmo1508),,,,PHI:11,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,There was no difference between wild type and the pieRS (lmo1507-lmo1508) mutant with respect bacterial burden in infected mice.,L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20776,PHI:123453,UniProt,Q8Y718,GenBank,CAC99586,,,EGD-e,lmo1508,,Deletion of pieRS (genes lmo1507 and lmo1508),,,,PHI:123452,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,histidine kinase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,There was no difference between wild type and the pieRS (lmo1507-lmo1508) mutant with respect bacterial burden in infected mice.,L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20777,PHI:123454,UniProt,Q8Y557,GenBank,CAD00297,,,EGD-e,prsA2,,Targetron insertion prsA2::T,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen,foldase protein,,,,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene mutation; gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA2 remained deficient for intracellular growth and bacterial burdens were reduced in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20778,PHI:123455,UniProt,Q8Y759,GenBank,CAC99522,,,EGD-e,prsA1,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,foldase protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,There was no difference between wild type and the mutant lacking prsA1 with respect bacterial burden in infected mice.,L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20779,PHI:123454,UniProt,Q8Y557,GenBank,CAD00297,,,EGD-e,prsA2,,,,,,PHI:123455,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,foldase protein,,,,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA1 and prsA2 remained deficient for intracellular growth and bacterial burdens were reduced in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20780,PHI:123455,UniProt,Q8Y759,GenBank,CAC99522,,,EGD-e,prsA1,,,,,,PHI:123454,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,foldase protein,,,,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA1 and prsA2 remained deficient for intracellular growth and bacterial burdens were reduced in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20781,PHI:123452,UniProt,Q8Y719,GenBank,CAC99585,,,EGD-e,lmo1507,,pieR* E81V,,,,PHI:123454,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen,response regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,NaCl,NaCl: CHEBI:26710,,,,,gene mutation: characterised; gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA2 and having E81V mutation in lmo1507 showed reduced bacterial burden in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20782,PHI:123454,UniProt,Q8Y557,GenBank,CAD00297,,,EGD-e,prsA2,,,,,,PHI:123452,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen,foldase protein,,,,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene mutation: characterised; gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA2 and having E81V mutation in lmo1507 showed reduced bacterial burden in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20783,PHI:123452,UniProt,Q8Y719,GenBank,CAC99585,,,EGD-e,lmo1507,,Deletion of pieRS (genes lmo1507 and lmo1508),,,,PHI:123453; PHI:123454,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,response regulator,,,,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA2 and pieRS (lmo1507-lmo1508) showed reduced bacterial burden in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20784,PHI:123453,UniProt,Q8Y718,GenBank,CAC99586,,,EGD-e,lmo1508,,Deletion of pieRS (genes lmo1507 and lmo1508),,,,PHI:123452; PHI:123454,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,histidine kinase,,,,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA2 and pieRS (lmo1507-lmo1508) showed reduced bacterial burden in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20785,PHI:123454,UniProt,Q8Y557,GenBank,CAD00297,,,EGD-e,prsA2,,,,,,PHI:123452; PHI:123453,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,foldase protein,,,,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA2 and pieRS (lmo1507-lmo1508) showed reduced bacterial burden in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20786,PHI:123452,UniProt,Q8Y719,GenBank,CAC99585,,,EGD-e,lmo1507,,Deletion of pieRS (genes lmo1507 and lmo1508),,,,PHI:123453; PHI:123455,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,response regulator,,,,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA1 and pieRS (lmo1507-lmo1508) showed reduced bacterial burden in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20787,PHI:123453,UniProt,Q8Y718,GenBank,CAC99586,,,EGD-e,lmo1508,,Deletion of pieRS (genes lmo1507 and lmo1508),,,,PHI:123452; PHI:123455,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,histidine kinase,,,,reduced virulence,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA1 and pieRS (lmo1507-lmo1508) showed reduced bacterial burden in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20788,PHI:123455,UniProt,Q8Y759,GenBank,CAC99522,,,EGD-e,prsA1,,,,,,PHI:123452; PHI:123453,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,liver; spleen; intestine,foldase protein,,,,reduced virulence,,,,,,,,wild type,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,35943959,PubMed,10.1111/mmi.14967,Mol Microbiol. 2022 Sep;118(3):278-293,nfreitag@uic.edu,"Mutant strains lacking prsA1 and pieRS (lmo1507-lmo1508) showed reduced bacterial burden in liver, spleen and intestine.",L A Cahoon 2022,2022,4 genes,Cahoon-2022-Listeria monocytogenes two compone,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20789,PHI:123456,,no data found,,,,,,ashA,,N455A; V457D,,,,,5059,Aspergillus flavus,,Δku70 ΔpyrG,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,histone methyltransferase,,,histone methylation,reduced virulence,,,,,,increased,,,,no,calcofluor white; Congo red; SDS; hydroxyurea,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; hydroxyurea: CHEBI:44423,,,,,gene deletion: full; gene complementation; gene deletion: partial; gene mutation: characterised,,,NN,35943142,PubMed,10.1016/j.isci.2021.103159,Virulence. 2022 Dec;13(1):1358-1378,wshyyl@sina.com,Deletion of ashA increased conidia production but produced no sclerotia and caused reduced virulence. The SET domain mutant (ashA ΔSET) and ashA mutant N455A/V457D also caused increased conidia production but produced no sclerotia and caused reduced virulence.,Z Zhuang 2022,2022,2 genes,Zhuang-2022-Set2 family regulates mycotoxin me,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20790,PHI:123456,,no data found,,,,,,ashA,,N455A; V457D,,,,,5059,Aspergillus flavus,,Δku70 ΔpyrG,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,histone methyltransferase,,,histone methylation,reduced virulence,,,,,,increased,,,,no,calcofluor white; Congo red; SDS; hydroxyurea,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; hydroxyurea: CHEBI:44423,,,,,gene deletion: full; gene complementation; gene deletion: partial; gene mutation: characterised,,,NN,35943142,PubMed,10.1016/j.isci.2021.103159,Virulence. 2022 Dec;13(1):1358-1378,wshyyl@sina.com,Deletion of ashA increased conidia production but produced no sclerotia and caused reduced virulence. The SET domain mutant (ashA ΔSET) and ashA mutant N455A/V457D also caused increased conidia production but produced no sclerotia and caused reduced virulence.,Z Zhuang 2022,2022,2 genes,Zhuang-2022-Set2 family regulates mycotoxin me,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20791,PHI:123456,,no data found,,,,,,ashA,,N455A; V457D,,,,,5059,Aspergillus flavus,,Δku70 ΔpyrG,ear rot (corn); yellow mold (peanut),moths,7091,Bombyx mori (related: domestic silkworm),,,,larva,histone methyltransferase,,,histone methylation,reduced virulence,,,,,,increased,,,,no,calcofluor white; Congo red; SDS; hydroxyurea,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; hydroxyurea: CHEBI:44423,,,,,gene deletion: full; gene complementation,,,NN,35943142,PubMed,10.1016/j.isci.2021.103159,Virulence. 2022 Dec;13(1):1358-1378,wshyyl@sina.com,Deletion of ashA increased conidia production but produced no sclerotia and caused reduced virulence.,Z Zhuang 2022,2022,2 genes,Zhuang-2022-Set2 family regulates mycotoxin me,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20792,PHI:123457,,no data found,,,,,,setB,,,,,,,5059,Aspergillus flavus,,Δku70 ΔpyrG,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,histone methyltransferase,,,histone methylation,reduced virulence,,,,,,reduced; defective,,,,no,calcofluor white; Congo red; SDS; hydroxyurea,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; hydroxyurea: CHEBI:44423,,,,,gene deletion: full; gene complementation; gene deletion: partial,,,NN,35943142,PubMed,10.1016/j.isci.2021.103159,Virulence. 2022 Dec;13(1):1358-1378,wshyyl@sina.com,Deletion of setB and the SET domain (setB ΔSET) decreased conidia production and caused reduced virulence in maize.,Z Zhuang 2022,2022,2 genes,Zhuang-2022-Set2 family regulates mycotoxin me,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20793,PHI:123456,,no data found,,,,,,ashA,,N455A; V457D,,,,PHI:123457,5059,Aspergillus flavus,,Δku70 ΔpyrG,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,histone methyltransferase,,,histone methylation,reduced virulence,,,,,,increased,,,,no,calcofluor white; Congo red; SDS; hydroxyurea,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; hydroxyurea: CHEBI:44423,,,,,gene deletion: full; gene complementation; gene deletion: partial; gene mutation: characterised,,,NN,35943142,PubMed,10.1016/j.isci.2021.103159,Virulence. 2022 Dec;13(1):1358-1378,wshyyl@sina.com,ΔsetB/ashA mutant decreased conidia production and caused reduced virulence in maize.,Z Zhuang 2022,2022,2 genes,Zhuang-2022-Set2 family regulates mycotoxin me,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20794,PHI:123457,,no data found,,,,,,setB,,,,,,PHI:123456,5059,Aspergillus flavus,,Δku70 ΔpyrG,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,kernel,histone methyltransferase,,,histone methylation,reduced virulence,,,,,,reduced; defective,,,,no,calcofluor white; Congo red; SDS; hydroxyurea,calcofluor white: CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; sodium dodecyl sulfate (SDS): CHEBI:8984; hydroxyurea: CHEBI:44423,,,,,gene deletion: full; gene complementation; gene deletion: partial,,,NN,35943142,PubMed,10.1016/j.isci.2021.103159,Virulence. 2022 Dec;13(1):1358-1378,wshyyl@sina.com,ΔsetB/ashA mutant decreased conidia production and caused reduced virulence in maize.,Z Zhuang 2022,2022,2 genes,Zhuang-2022-Set2 family regulates mycotoxin me,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20795,PHI:123458,UniProt,B0XX88,GenBank,EDP52555,,,A1163,pacC (AFUB_037210),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,pH-responsive transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20796,PHI:123459,UniProt,B0YDQ1,GenBank,EDP47785,,,A1163,AreA (AFUB_096370),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,broad domain regulator of nitrogen metabolism,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20797,PHI:123460,UniProt,B0XSK6,GenBank,EDP54692,,,A1163,CreA(AFUB_027530),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,broad domain regulator of carbon catabolism,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20798,PHI:123461,UniProt,B0XZH9,GenBank,EDP52229,,,A1163,BGC12 (AFUB_033930),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,C6 zinc cluster family transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20799,PHI:123462,UniProt,B0Y0A6,GenBank,EDP52370,,,A1163,NsdD (AFUB_035330),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20800,PHI:123463,UniProt,B0YC99,GenBank,EDP48230,,,A1163,NsdC (AFUB_089440),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20801,PHI:123464,UniProt,B0Y0H0,GenBank,EDP53440,,,A1163,C6 transcription factor (AFUB_046160),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,C6 transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20802,PHI:123465,UniProt,B0XU15,GenBank,EDP53440,,,A1163,C2H2 finger domain protein (AFUB_019830),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,C2H2 finger domain protein,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20803,PHI:123466,UniProt,B0XUI4,GenBank,EDP55039,,,A1163,AflR-like C6 transcription factor (AFUB_031000),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,AflR-like C6 transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20804,PHI:123467,UniProt,B0XP08,GenBank,EDP55851,,,A1163,C2H2 transcription factor (TFIIIA) (AFUB_005510),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,C2H2 transcription factor (TFIIIA),,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20805,PHI:123468,UniProt,B0Y2Z7,GenBank,EDP51238,,,A1163,HapX (AFUB_052420),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,bZip transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20806,PHI:123469,UniProt,B0XVY8,GenBank,EDP55281,,,A1163,C6 transcription factor (AFUB_052420),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,C6 transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20807,PHI:123470,UniProt,B0XUZ6,GenBank,EDP55136,,,A1163,fungal specific transcription factor (AFUB_031980),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,fungal specific transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20808,PHI:123471,UniProt,B0XYJ1,GenBank,EDP52937,,,A1163,sltA (AFUB_041100),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,C2H2 transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20809,PHI:123472,UniProt,B0Y8Q2,GenBank,EDP49783,,,A1163,atfD (AFUB_078150),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,bZip transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20810,PHI:123473,UniProt,B0Y8T8,GenBank,EDP49819,,,A1163,stress response regulator/HFS transcription factor (AFUB_078520),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,stress response regulator/HFS transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20811,PHI:123474,UniProt,B0XNV0,GenBank,EDP56854,,,A1163,C6 transcription factor (AFUB_015750),,,,,,,746128,Aspergillus fumigatus,,A1160P+,pulmonary aspergillosis,primates,9606,Homo sapiens (related: human),A-549 cell line,,,lung epithelial cell,C6 transcription factor,,,,reduced virulence,,yes,,yes,,,,,reduced,no,,,,,,,gene deletion: full,,,NN,35982778,PubMed,10.3389/fcimb.2022.907519,Front Cell Infect Microbiol. 2022 Jul 28;12:907519,e.bignell@exeter.ac.uk,Transcription factor mutants were found to exhibit reproducible deficits in epithelial damage causation.,S Rahman 2022,2022,17 genes,Rahman-2022-Distinct Cohorts of Aspergillus fu,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20812,PHI:123475,UniProt,G3XCT7,GenBank,AAG07781,,,PAO1,ampG,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,Knock-out of ampG attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20813,PHI:123476,UniProt,Q9HZK0,GenBank,AAG06393,,,PAO1,nagZ,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,Knock-out of nagZ attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20814,PHI:123475,UniProt,G3XCT7,GenBank,AAG07781,,,PAO1,ampG,,,,,,,287,Pseudomonas aeruginosa,652611,PA14,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,Knock-out of ampG attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20815,PHI:123475,UniProt,G3XCT7,GenBank,AAG07781,,,PAO1,ampG,,ampG knock-out mutant strain harboring cloned Oxa-2,,,,PHI:123477,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-2 attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20816,PHI:123477,UniProt,Q7AYX1,GenBank,ACH43056,,,3536,Oxa-2,,ampG knock-out mutant strain harboring cloned Oxa-2,,,,PHI:123475,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-2 attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20817,PHI:123476,UniProt,Q9HZK0,GenBank,AAG06393,,,PAO1,nagZ,,nagZ knock-out mutant strain harboring cloned Oxa-2,,,,PHI:123477,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,nagZ knock-out mutant strain harboring cloned Oxa-2 attenuated P. aeruginosa's killing capacity against Galleria mellonella similar to the strain which did not harbor Oxa-2.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20818,PHI:123477,UniProt,Q7AYX1,GenBank,ACH43056,,,3536,Oxa-2,,nagZ knock-out mutant strain harboring cloned Oxa-2,,,,PHI:123476,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,nagZ knock-out mutant strain harboring cloned Oxa-2 attenuated P. aeruginosa's killing capacity against Galleria mellonella similar to the strain which did not harbor Oxa-2.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20819,PHI:123475,UniProt,G3XCT7,GenBank,AAG07781,,,PAO1,ampG,,ampG knock-out mutant strain harboring cloned Oxa-226 (W159R),,,,PHI:123478,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-226 (W159R) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20820,PHI:123478,UniProt,B9VXW8,GenBank,ACM67635,,,3536,Oxa-226,,ampG knock-out mutant strain harboring cloned Oxa-226 (W159R),,,,PHI:123475,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-226 (W159R) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20821,PHI:123475,UniProt,G3XCT7,GenBank,AAG07781,,,PAO1,ampG,,ampG knock-out mutant strain harboring cloned Oxa-161 (N148D),,,,PHI:123479,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-161 (N148D) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20822,PHI:123479,UniProt,C6KFD9,GenBank,ACT09125,,,PAOXA161,Oxa-161,,ampG knock-out mutant strain harboring cloned Oxa-161 (N148D),,,,PHI:123475,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-161 (N148D) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20823,PHI:123475,UniProt,G3XCT7,GenBank,AAG07781,,,PAO1,ampG,,ampG knock-out mutant strain harboring cloned Oxa-539 (D149 duplication),,,,PHI:123480,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-539 (D149 duplication) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20824,PHI:123480,UniProt,A0A1J0F615,GenBank,APC23886,,,16373330,Oxa-539,,ampG knock-out mutant strain harboring cloned Oxa-539 (D149 duplication),,,,PHI:123475,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-539 (D149 duplication) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20825,PHI:123476,UniProt,Q9HZK0,GenBank,AAG06393,,,PAO1,nagZ,,nagZ knock-out mutant strain harboring cloned Oxa-226 (W159R),,,,PHI:123478,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,nagZ knock-out mutant strain harboring cloned Oxa-226 (W159R) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20826,PHI:123478,UniProt,B9VXW8,GenBank,ACM67635,,,3536,Oxa-226,,nagZ knock-out mutant strain harboring cloned Oxa-226 (W159R),,,,PHI:123476,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,nagZ knock-out mutant strain harboring cloned Oxa-226 (W159R) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20827,PHI:123476,UniProt,Q9HZK0,GenBank,AAG06393,,,PAO1,nagZ,,nagZ knock-out mutant strain harboring cloned Oxa-161 (N148D),,,,PHI:123479,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,nagZ knock-out mutant strain harboring cloned Oxa-161 (N148D) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20828,PHI:123479,UniProt,C6KFD9,GenBank,ACT09125,,,PAOXA161,Oxa-161,,nagZ knock-out mutant strain harboring cloned Oxa-161 (N148D),,,,PHI:123476,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,nagZ knock-out mutant strain harboring cloned Oxa-161 (N148D) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20829,PHI:123476,UniProt,Q9HZK0,GenBank,AAG06393,,,PAO1,nagZ,,nagZ knock-out mutant strain harboring cloned Oxa-539 (D149 duplication),,,,PHI:123480,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,permease,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,nagZ knock-out mutant strain harboring cloned Oxa-539 (D149 duplication) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20830,PHI:123480,UniProt,A0A1J0F615,GenBank,APC23886,,,16373330,Oxa-539,,nagZ knock-out mutant strain harboring cloned Oxa-539 (D149 duplication),,,,PHI:123476,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,nagZ knock-out mutant strain harboring cloned Oxa-539 (D149 duplication) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20831,PHI:123477,UniProt,Q7AYX1,GenBank,ACH43056,,,3536,Oxa-2,,cloned oxa-2,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,nagZ knock-out mutant strain harboring cloned Oxa-2 attenuated P. aeruginosa's killing capacity against Galleria mellonella similar to the strain which did not harbor Oxa-2.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20832,PHI:123478,UniProt,B9VXW8,GenBank,ACM67635,,,3536,Oxa-226,,cloned Oxa-226 (W159R),,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-226 (W159R) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20833,PHI:123479,UniProt,C6KFD9,GenBank,ACT09125,,,PAOXA161,Oxa-161,,cloned Oxa-161 (N148D),,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-161 (N148D) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20834,PHI:123480,UniProt,A0A1J0F615,GenBank,APC23886,,,16373330,Oxa-539,,cloned Oxa-539 (D149 duplication),,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,,beta-lactamase,,,,reduced virulence,,,,,,,,,,no,,,,,,,other evidence: cloning,,,NN,35171032,PubMed,10.1128/spectrum.02019-21,Microbiol Spectr. 2022 Feb 23;10(1):e0201921,antonio.oliver@ssib.es,ampG knock-out mutant strain harboring cloned Oxa-539 (D149 duplication) attenuated P. aeruginosa's killing capacity against Galleria mellonella.,I M Barceló 2022,2022,6 genes,Barceló-2022-Impact of Peptidoglycan Recycling,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20835,PHI:123481,UniProt,Q5DIP3,GenBank,AAX16361,,,MSH,pvdI,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,PvdI(2),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35948833,PubMed,10.1007/s00248-022-02095-5,Microb Ecol. 2022 Aug 11,jesus.campos@umich.mx,ΔpvdI showed decreased internal compaction,S P Díaz-Pérez 2022,2022,3 genes,Díaz-Pérez-2022-Pathogenesis in Pseudomonas ae,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20836,PHI:123482,UniProt,Q9I181,GenBank,AE004666_4,,,PAO1,pvdJ,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,PvdJ,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35948833,PubMed,10.1007/s00248-022-02095-5,Microb Ecol. 2022 Aug 11,jesus.campos@umich.mx,The biofilm structure of the ΔpvdJ mutant displays similar characteristics to the WT strain,S P Díaz-Pérez 2022,2022,3 genes,Díaz-Pérez-2022-Pathogenesis in Pseudomonas ae,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20837,PHI:123483,UniProt,Q9I157,GenBank,AE004669_9,,,PAO1,pvdL,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,PvdL,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35948833,PubMed,10.1007/s00248-022-02095-5,Microb Ecol. 2022 Aug 11,jesus.campos@umich.mx,"ΔpvdL mutant exhibited the most substantial impairment in fluorescence intensity, thickness, and internal biofilm complexity; its biofilm contained rough structures, like mountains, and delicate linear structures like thin fibers",S P Díaz-Pérez 2022,2022,3 genes,Díaz-Pérez-2022-Pathogenesis in Pseudomonas ae,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20838,PHI:123481,UniProt,Q5DIP3,GenBank,AAX16361,,,MSH,pvdI,,,,,,PHI:123482,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,PvdI(2),,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35948833,PubMed,10.1007/s00248-022-02095-5,Microb Ecol. 2022 Aug 11,jesus.campos@umich.mx,biofilm similar to wild type,S P Díaz-Pérez 2022,2022,3 genes,Díaz-Pérez-2022-Pathogenesis in Pseudomonas ae,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20839,PHI:123482,UniProt,Q9I181,GenBank,AE004666_4,,,PAO1,pvdJ,,,,,,PHI:123481,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,PvdJ,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35948833,PubMed,10.1007/s00248-022-02095-5,Microb Ecol. 2022 Aug 11,jesus.campos@umich.mx,biofilm similar to wild type,S P Díaz-Pérez 2022,2022,3 genes,Díaz-Pérez-2022-Pathogenesis in Pseudomonas ae,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20840,PHI:123482,UniProt,Q9I181,GenBank,AE004666_4,,,PAO1,pvdJ,,,,,,PHI:123483,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,PvdJ,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35948833,PubMed,10.1007/s00248-022-02095-5,Microb Ecol. 2022 Aug 11,jesus.campos@umich.mx,biofilm similar to wild type,S P Díaz-Pérez 2022,2022,3 genes,Díaz-Pérez-2022-Pathogenesis in Pseudomonas ae,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20841,PHI:123483,UniProt,Q9I157,GenBank,AE004669_9,,,PAO1,pvdL,,,,,,PHI:123482,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,PvdL,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35948833,PubMed,10.1007/s00248-022-02095-5,Microb Ecol. 2022 Aug 11,jesus.campos@umich.mx,biofilm similar to wild type,S P Díaz-Pérez 2022,2022,3 genes,Díaz-Pérez-2022-Pathogenesis in Pseudomonas ae,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20842,PHI:123481,UniProt,Q5DIP3,GenBank,AAX16361,,,MSH,pvdI,,,,,,PHI:123483,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,PvdI(2),,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35948833,PubMed,10.1007/s00248-022-02095-5,Microb Ecol. 2022 Aug 11,jesus.campos@umich.mx,ΔpvdL/ΔpvdI severely affected their biofilm structure (producing thin biofilm layers with irregular morphology),S P Díaz-Pérez 2022,2022,3 genes,Díaz-Pérez-2022-Pathogenesis in Pseudomonas ae,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20843,PHI:123483,UniProt,Q9I157,GenBank,AE004669_9,,,PAO1,pvdL,,,,,,PHI:123481,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,larva,PvdL,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35948833,PubMed,10.1007/s00248-022-02095-5,Microb Ecol. 2022 Aug 11,jesus.campos@umich.mx,ΔpvdL/ΔpvdI severely affected their biofilm structure (producing thin biofilm layers with irregular morphology),S P Díaz-Pérez 2022,2022,3 genes,Díaz-Pérez-2022-Pathogenesis in Pseudomonas ae,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20844,PHI:123484,UniProt,A0A384K208,GenBank,ATZ56870,,,B05.10,Bcpg1,BCIN14,,,,,PHI:123485,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,polygalacturonase1,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,"Unripe fruit (Mature green), AC-SIPG2A, a tomato line with suppressed expression of the main ripening-associated PG",C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20845,PHI:123485,UniProt,A0A384K232,GenBank,ATZ56840,,,B05.10,Bcpg2,BCIN14,,,,,PHI:123484,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,polygalacturonase2,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,"Unripe fruit (Mature green), AC-SIPG2A, a tomato line with suppressed expression of the main ripening-associated PG",C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20846,PHI:123486,UniProt,Q9C2Y1,GenBank,CAC29255,,,T4,Bcpme1,BCIN09,,,,,PHI:123487,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,pectinesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,In unripe fruit (Mature green) and Red ripe fruit,C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20847,PHI:123487,UniProt,Q8X116,GenBank,CAD21438,,,Bd90,Bcpme2,,,,,,PHI:123486,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,pectinesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,In unripe fruit (Mature green) and Red ripe fruit,C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20848,PHI:123484,UniProt,A0A384K208,GenBank,ATZ56870,,,B05.10,Bcpg1,BCIN14,,,,,PHI:123486,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,polygalacturonase1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,In unripe fruit (Mature green) and Red ripe fruit,C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20849,PHI:123486,UniProt,Q9C2Y1,GenBank,CAC29255,,,T4,Bcpme1,BCIN09,,,,,PHI:123484,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,pectinesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,In unripe fruit (Mature green) and Red ripe fruit,C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20850,PHI:123486,UniProt,Q9C2Y1,GenBank,CAC29255,,,T4,Bcpme1,BCIN09,,,,,PHI:123487,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,pectinesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,"AC-SIPG2A, a tomato line with suppressed expression of the main ripening-associated PG",C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20851,PHI:123487,UniProt,Q8X116,GenBank,CAD21438,,,Bd90,Bcpme2,,,,,,PHI:123486,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,pectinesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,"AC-SIPG2A, a tomato line with suppressed expression of the main ripening-associated PG",C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20852,PHI:123484,UniProt,A0A384K208,GenBank,ATZ56870,,,B05.10,Bcpg1,BCIN14,,,,,PHI:123486,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,polygalacturonase1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,"AC-SIPG2A, a tomato line with suppressed expression of the main ripening-associated PG",C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20853,PHI:123486,UniProt,Q9C2Y1,GenBank,CAC29255,,,T4,Bcpme1,BCIN09,,,,,PHI:123484,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,pectinesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,"AC-SIPG2A, a tomato line with suppressed expression of the main ripening-associated PG",C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20854,PHI:123484,UniProt,A0A384K208,GenBank,ATZ56870,,,B05.10,Bcpg1,BCIN14,,,,,PHI:123485,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,polygalacturonase1,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,In Red ripe fruit,C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20855,PHI:123485,UniProt,A0A384K232,GenBank,ATZ56840,,,B05.10,Bcpg2,BCIN14,,,,,PHI:123484,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,fruit,polygalacturonase2,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36053186,PubMed,10.1093/plphys/kiac408,Plant Physiol. 2022 Sep 2;kiac408,bblanco@ucdavis.edu,In Red ripe fruit,C Silva 2022,2022,4 genes,Silva-2022-Botrytis cinerea infection accelera,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20856,PHI:123488,UniProt,P20581,GenBank,AAA88447,,,PAO1,pqsE,,E182W; R243A/R246A/R247A,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,2-aminobenzoylacetyl-CoA thioesterase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene mutation,,,NN,35985643,PubMed,10.1021/acs.biochem.2c00334,Biochemistry. 2022 Sep 6;61(17):1894-1903,bbassler@princeton.edu,"PqsE-RhlR interaction, and not PqsEcatalytic activity, is responsible for shaping the pathogenicity ofP. aeruginosa PA14 in vitro and in vivo",I R Taylor 2022,2022,1 gene,Taylor-2022-The PqsE Active Site as a Target f,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20857,PHI:123488,UniProt,P20581,GenBank,AAA88447,,,PAO1,pqsE,,D73A,,,,,287,Pseudomonas aeruginosa,208963,UCBPP-PA14,opportunistic infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,2-aminobenzoylacetyl-CoA thioesterase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,35985643,PubMed,10.1021/acs.biochem.2c00334,Biochemistry. 2022 Sep 6;61(17):1894-1903,bbassler@princeton.edu,"PqsE-RhlR interaction, and not PqsEcatalytic activity, is responsible for shaping the pathogenicity ofP. aeruginosa PA14 in vitro and in vivo",I R Taylor 2022,2022,1 gene,Taylor-2022-The PqsE Active Site as a Target f,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20858,PHI:123489,,no data found,,,,,,gemA,,,,,,,746128,Aspergillus fumigatus,,A1160 (Δaku80 pyrG),invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative mitochondrial GTPase,,,,reduced virulence,,,,,,,,defective,,no,voriconazole; itraconazole; bifonazole; terbinafine; amphotericin B; KCl; NaCl; sorbitol; Congo red,voriconazole: CHEBI:10023; itraconazole: CHEBI:6076; bifonazole: CHEBI:31286; terbinafine: CHEBI:9448; amphotericin B: CHEBI:2682; KCl: CHEBI:32588; NaCl: CHEBI:26710; sorbitol: CHEBI:17924; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,36016773,PubMed,10.3389/fmicb.2022.957857,Front Microbiol. 2022 Aug 9;13:957857,xuelianchang@126.com,"GemA is required for hyphal growth, virulence, and cell wall integrity. Importantly, GemA exhibited a critical function in azole resistance by affecting the expression of a series of drug efflux pumps",X Zhou 2022,2022,1 gene,Zhou-2022-Requirement of a putative mitochondr,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20859,PHI:123490,UniProt,A0A7G5WGW9,,,,,,SIX5,,without its endogenous signal peptide,,,,,5507,Fusarium oxysporum,660025,Fo5176,Fusarium wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial,,,NN,35968143,PubMed,10.3389/fpls.2022.910594,Front Plant Sci. 2022 Jul 29;13:910594,f.l.w.takken@uva.nl,"Avr2 effector also has an additional function in suppressing PTI signaling induced by various PAMPs, the major function of Six5 appears to be to act together with Avr2 to facilitate cell-to-cell movement of Avr2 and maybe of other effectors.",M C Blekemolen 2022,2022,2 genes,Blekemolen-2022-The primary function of Six5 o,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20860,PHI:123490,UniProt,A0A7G5WGW9,,,,,,SIX5,,without its endogenous signal peptide,,,,PHI:123491,5507,Fusarium oxysporum,660025,Fo5176,Fusarium wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial,,,NN,35968143,PubMed,10.3389/fpls.2022.910594,Front Plant Sci. 2022 Jul 29;13:910594,f.l.w.takken@uva.nl,"Avr2 effector also has an additional function in suppressing PTI signaling induced by various PAMPs, the major function of Six5 appears to be to act together with Avr2 to facilitate cell-to-cell movement of Avr2 and maybe of other effectors.",M C Blekemolen 2022,2022,2 genes,Blekemolen-2022-The primary function of Six5 o,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20861,PHI:123491,UniProt,A0A0C4DI32,,,,,,Avr2(SIX3),,without its endogenous signal peptide,,,,PHI:123490,5507,Fusarium oxysporum,660025,Fo5176,Fusarium wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial,,,NN,35968143,PubMed,10.3389/fpls.2022.910594,Front Plant Sci. 2022 Jul 29;13:910594,f.l.w.takken@uva.nl,"Avr2 effector also has an additional function in suppressing PTI signaling induced by various PAMPs, the major function of Six5 appears to be to act together with Avr2 to facilitate cell-to-cell movement of Avr2 and maybe of other effectors.",M C Blekemolen 2022,2022,2 genes,Blekemolen-2022-The primary function of Six5 o,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20862,PHI:123492,UniProt,F2YQ16,GenBank,AEA51000,,,ACR12,Avr3a,,,,,,,67593,Phytophthora sojae,,PI339078a,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; altered gene expression / gene regulation: overexpression; other evidence: fungal crossing,,,NN,35150190,PubMed,10.1111/mpp.13190,Mol Plant Pathol. 2022 May;23(5):693-706,Richard.belanger@fsaa.ulaval.ca,P. sojae isolates 45C (avirulent on Rps8),G Arsenault-Labrecque 2022,2022,2 genes,Arsenault-Labre-2022-RXLR effector gene Avr3a,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20863,PHI:123492,UniProt,F2YQ16,GenBank,AEA51000,,,ACR12,Avr3a,,,,,,,67593,Phytophthora sojae,,PI339078a,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,NN,35150190,PubMed,10.1111/mpp.13190,Mol Plant Pathol. 2022 May;23(5):693-706,Richard.belanger@fsaa.ulaval.ca,P. sojae isolates 7B (virulent on Rps8),G Arsenault-Labrecque 2022,2022,2 genes,Arsenault-Labre-2022-RXLR effector gene Avr3a,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20864,PHI:123493,UniProt,G1FQZ9,GenBank,AEK80536,,,P7064,Avh37,,,,,,,67593,Phytophthora sojae,,PI339078a,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; altered gene expression / gene regulation: overexpression; other evidence: fungal crossing,,,NN,35150190,PubMed,10.1111/mpp.13190,Mol Plant Pathol. 2022 May;23(5):693-706,Richard.belanger@fsaa.ulaval.ca,P. sojae isolates 45C (avirulent on Rps8),G Arsenault-Labrecque 2022,2022,2 genes,Arsenault-Labre-2022-RXLR effector gene Avr3a,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20865,PHI:123493,UniProt,G1FQZ9,GenBank,AEK80536,,,P7064,Avh37,,,,,,,67593,Phytophthora sojae,,PI339078a,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; other evidence: fungal crossing,,,NN,35150190,PubMed,10.1111/mpp.13190,Mol Plant Pathol. 2022 May;23(5):693-706,Richard.belanger@fsaa.ulaval.ca,P. sojae isolates 7B (virulent on Rps8),G Arsenault-Labrecque 2022,2022,2 genes,Arsenault-Labre-2022-RXLR effector gene Avr3a,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20866,PHI:123494,UniProt,A0A0D1CS12,GenBank,KIS69353,,,521,cda1,chromosome 6,,,,,,5270,Ustilago maydis,559306,FB1,smut,monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,seedling,chitin deacetylase,,,,reduced virulence,,,,,,,,aberrant,,no,NaCl; LiCl; KCl; sorbitol,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,36012801,PubMed,10.3390/jof8080813,J Fungi (Basel). 2022 Aug 2;8(8):813,alejandro.sanchez@cinvestav.mx,"chitosan is an important component for the correct formation of the cell wall structure of the mycelial morphology, and to avoidrecognition by its host during the pathogenic process of U. maydis",J A Sánchez-Arreguin 2022,2022,1 gene,Sánchez-Arregui-2022-Chitosan Is Necessary for,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20867,PHI:123494,UniProt,A0A0D1CS12,GenBank,KIS69353,,,521,cda1,chromosome 6,,,,,,5270,Ustilago maydis,,FB2,smut,monocots,4577,Zea mays (related: maize),cv. Cacahuazintle,,,seedling,chitin deacetylase,,,,reduced virulence,,,,,,,,aberrant,,no,NaCl; LiCl; KCl; sorbitol,NaCl: CHEBI:26710; LiCl: CHEBI:48607; KCl: CHEBI:32588; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,36012801,PubMed,10.3390/jof8080813,J Fungi (Basel). 2022 Aug 2;8(8):813,alejandro.sanchez@cinvestav.mx,"chitosan is an important component for the correct formation of the cell wall structure of the mycelial morphology, and to avoidrecognition by its host during the pathogenic process of U. maydis",J A Sánchez-Arreguin 2022,2022,1 gene,Sánchez-Arregui-2022-Chitosan Is Necessary for,BATCH_115B,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20868,PHI:123495,UniProt,G1X8J9,GenBank,EGX50562,,,ATCC 24927,AoRvs167 (AOL_s00075g198),,,,,,,2813651,Orbilia oligospora,756982,ATCC 24927,nematode trapping fungus,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,Bin/amphiphysin/Rvs (BAR) domaincontaining protein,,,,loss of pathogenicity,,,,,,reduced,,reduced,,no,Congo red; NaCl,Congo red: CHEBI:34653; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation; gene mutation: characterised,,,NN,36145429,PubMed,10.3390/pathogens11090997,Pathogens. 2022 Aug 31;11(9):997,ligh@ynu.edu.cn,"Deletion of AoRvs167 caused reduction in conidiation and fungal growth. ΔAoRvs167 had almost no adhesive network after nematodes induced and as a consequence, nematode animals could not be killed by the mutant strain in the test.",Pcui 2022,2022,1 gene,Cui-2022-Amphiphysin AoRvs167-Mediated Membran,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20869,PHI:123496,UniProt,A0A8F9XRT5,GenBank,QYM87222,,,B500,DksA,,,,,,,139,Borreliella burgdorferi,,CE162,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin; heart; joint,DnaK suppressor,,,,loss of pathogenicity,,,,,,,,reduced,,no,NaCl,NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,NN,32227372,PubMed,10.1111/mmi.14504,Mol Microbiol. 2020 Jul;114(1):172-183,zouyang@usf.edu,Inactivation of dksA rendered B. burgdorferi completely noninfectious in mice.,C Mason 2022,2022,1 gene,Mason-2020-DksA plays an essential role in reg,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20870,PHI:123497,UniProt,Q4WUG7,GenBank,EAL91759,,,Af293,SskA,chromosome 5,,,,,,746128,Aspergillus fumigatus,,,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,"response regulator, putative",,,SakA mitogen-activated protein kinase (MAPK) pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,34878292,PubMed,10.1128/msphere.00922-21,mSphere. 2021 Dec 22;6(6):e0092221,joshua.j.obar@dartmouth.edu,"When AF293 ΔsskA was grown in lung homogenate medium, robust germination was observed compared to the parental strain",M E Kirkland 2021,2021,3 genes,Kirkland-2021-Host Lung Environment Limits Asp,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20871,PHI:123498,UniProt,B0XR80,GenBank,EDP56531,,,A1163,SakA,,,,,,,746128,Aspergillus fumigatus,,,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,MAP kinase SakA,,,SakA mitogen-activated protein kinase (MAPK) pathway,increased virulence (hypervirulence),,,,,,,,increased,,no,NaCl; KCl; sorbitol; CaCl2,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:17924; CaCl2: CHEBI:3312,,,,,gene deletion: full,,,NN,34878292,PubMed,10.1128/msphere.00922-21,mSphere. 2021 Dec 22;6(6):e0092221,joshua.j.obar@dartmouth.edu,AF293 strains with ΔsakA mutant germinated to a significantly greater degree than their parental strains in murine airways.,M E Kirkland 2021,2021,3 genes,Kirkland-2021-Host Lung Environment Limits Asp,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20872,PHI:123499,UniProt,B0Y462,GenBank,EDP51653,,,A1163,MpkC,,,,,,,746128,Aspergillus fumigatus,,,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,MAP kinase MpkC,,,SakA mitogen-activated protein kinase (MAPK) pathway,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full,,,NN,34878292,PubMed,10.1128/msphere.00922-21,mSphere. 2021 Dec 22;6(6):e0092221,joshua.j.obar@dartmouth.edu,AF293 strains with ΔMpkC mutant germinated to a significantly greater degree than their parental strains in murine airways.,M E Kirkland 2021,2021,3 genes,Kirkland-2021-Host Lung Environment Limits Asp,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20873,PHI:123500,UniProt,C5ABM8,GenBank,ACR27839,,,BGR1,dbcA(bglu_1g06460),chromosome 1,,,,,,337,Burkholderia glumae,626418,BGR1,bacterial panicle blight (rice),monocots,4530,Oryza sativa (related: rice),,,,panicle,membrane transporter,,,,reduced virulence,,,,,,,,wild type,,no,colistin,colistin: CHEBI:37943,,,,,gene deletion: full; gene complementation,,,NN,34260305,PubMed,10.1128/AEM.00915-21,Appl Environ Microbiol. 2021 Aug 26;87(18):e0091521,wdoerr@lsu.edu,The B. Glumae ΔdbcAstrain was compromised for virulence in rice plant and secreted only low amounts of toxoflavin.,A Iqbal 2021,2021,1 gene,Iqbal-2021-Chemical or Genetic Alteration of P,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20874,PHI:123501,UniProt,A0A098SF15,GenBank,AKA32974,,,AB5075-UW,lirL (ABUW_3278),,,,,,,470,Acinetobacter baumannii,,Ab17978,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,lipoprotein,,,,reduced virulence,,,,,,,,reduced; defective,,no,vancomycin; gentamicin; amikacin; NaCl,vancomycin: CHEBI:28001; gentamicin: CHEBI:17833; amikacin: CHEBI:2637; NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,36099298,PubMed,10.1073/pnas.2123117119,Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2123117119,kapadia.sharookh@gene.com,Ab17978 ΔlirL was highly attenuated in a pneumonia mouse model.,K-J Huang 2022,2022,1 gene,Huang-2022-Deletion of a previously uncharacte,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20875,PHI:123502,UniProt,Q8XVT6,GenBank,CAD16448,,,GMI1000,proA,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,,gamma-glutamyl phosphate reductase,,,PrhG-HrpB pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation; gene mutation: characterised,,,NN,36106083,PubMed,10.3389/fmicb.2022.945831,Front Microbiol. 2022 Aug 29;13:945831,hellolijing@126.com,Deletion of proA significantly impaired the ability of R. solanacearum to invade and colonize host xylem vessels.,Y Guan 2022,2022,1 gene,Guan-2022-Functional characterization of a gam,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20876,PHI:123503,UniProt,P52698,GenBank,CAD16455,,,GMI1000,phcA,,,,,,,305,Ralstonia solanacearum,,EP1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,,LysR-type transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36177460,PubMed,10.3389/fmicb.2022.977580,Front Microbiol. 2022 Sep 13;13:977580,lishengliao@scau.edu.cn,"Deletion of phcA caused much decreased EPS production, reduced cellulase activity, and attenuated pathogenicity in eggplant.",J Yan 2022,2022,2 genes,Yan-2022-Markerless gene deletion in Ralstonia,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20877,PHI:123504,UniProt,Q45409,GenBank,AAA91625,,,AW,EpsB,,,,,,,305,Ralstonia solanacearum,,EP1,bacterial wilt,eudicots,4111,Solanum melongena (related: eggplant),,,,,putative tyrosine-protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36177460,PubMed,10.3389/fmicb.2022.977580,Front Microbiol. 2022 Sep 13;13:977580,lishengliao@scau.edu.cn,"Deletion of epsB caused much decreased EPS production, reduced cellulase activity, and attenuated pathogenicity in eggplant.",J Yan 2022,2022,2 genes,Yan-2022-Markerless gene deletion in Ralstonia,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20878,PHI:123505,UniProt,A0A0K0GJ58,GenBank,ACD58207,,,,hcp1 (PXO_00264),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,type VI secretion system tube protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36177860,PubMed,10.1111/mpp.13272,Mol Plant Pathol. 2022 Sep 30,ruanlifang@mail.hzau.edu.cn,Plant inoculation revealed that hcp1 was not required for the full virulence of the Xoo PXO99A strain.,Y Shao 2022,2022,2 genes,Shao-2022-Transcriptional regulator Sar regula,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20879,PHI:123506,UniProt,A0A0K0GN93,GenBank,ACD60330,,,,hcp2 (PXO_02047),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial blight (rice),monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,type VI secretion system tube protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36177860,PubMed,10.1111/mpp.13272,Mol Plant Pathol. 2022 Sep 30,ruanlifang@mail.hzau.edu.cn,Plant inoculation revealed that hcp2 was not required for the full virulence of the Xoo PXO99A strain.,Y Shao 2022,2022,2 genes,Shao-2022-Transcriptional regulator Sar regula,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20880,PHI:123507,UniProt,Q5ZV89,GenBank,AAU27633,,,Philadelphia 1,RavY,,ravY::Tn,,,,,446,Legionella pneumophila,,Lp01,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,34543123,PubMed,10.1128/IAI.00261-21,Infect Immun. 2021 Nov 16;89(12):e0026121,craig.roy@yale.edu,The ΔravY mutant exhibited a 2-log growth defect compared with the WT strain at 72 h postinfection in murine macrophages.,L Liu 2021,2021,2 genes,Liu-2021-The Legionella pneumophila Effector R,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20881,PHI:123508,UniProt,Q5ZS33,GenBank,AAU28744,,,Philadelphia 1,DotA,,dotA::tn,,,,,446,Legionella pneumophila,,Lp01,Legionnaires' disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage,conjugal transfer/type IV secretion protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,NN,34543123,PubMed,10.1128/IAI.00261-21,Infect Immun. 2021 Nov 16;89(12):e0026121,craig.roy@yale.edu,The ΔdotA mutant exhibited growth defect compared with the WT strain in murine macrophages.,L Liu 2021,2021,2 genes,Liu-2021-The Legionella pneumophila Effector R,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20882,PHI:123509,UniProt,G2X7W6,GenBank,EGY15084,,,VdLs.17,VdDrs2 (VDAG_06574),chromosome 8,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling; leaf,phospholipid-transporting ATPase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36072318,PubMed,10.3389/fpls.2022.944364,Front Plant Sci. 2022 Aug 22;13:944364,peiyan3@swu.edu.cn,Root dip infection assay showed that VW symptom caused by ΔVdDrs2 was significantly less severe than that by the wild type and complemented strain.,H Ren 2022,2022,4 genes,"Ren-2022-Loss of function of VdDrs2, a P4-ATPa",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20883,PHI:123510,UniProt,G2X7W6,GenBank,EGY15084,,,VdLs.17,VdDrs2 (VDAG_06574),chromosome 8,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,seedling,phospholipid-transporting ATPase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36072318,PubMed,10.3389/fpls.2022.944364,Front Plant Sci. 2022 Aug 22;13:944364,peiyan3@swu.edu.cn,Root dip infection assay showed that VW symptom caused by ΔVdDrs2 was significantly less severe than that by the wild type and complemented strain.,H Ren 2022,2022,4 genes,"Ren-2022-Loss of function of VdDrs2, a P4-ATPa",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20884,PHI:123511,UniProt,G2XG41,GenBank,EGY18860,,,VdLs.17,VdNeo1 (VDAG_09020),chromosome 5,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,UTH1 protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,36072318,PubMed,10.3389/fpls.2022.944364,Front Plant Sci. 2022 Aug 22;13:944364,peiyan3@swu.edu.cn,Loss of function of VdNeo1 significantly decreased the pathogenicity of the pathogen in cotton.,H Ren 2022,2022,4 genes,"Ren-2022-Loss of function of VdDrs2, a P4-ATPa",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20885,PHI:123512,UniProt,G2WQF3,GenBank,EGY13913,,,VdLs.17,VdP4-4 (VDAG_00595),chromosome 2,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,large-conductance mechanosensitive channel,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,36072318,PubMed,10.3389/fpls.2022.944364,Front Plant Sci. 2022 Aug 22;13:944364,peiyan3@swu.edu.cn,Loss of function of VdP4-4 significantly decreased the pathogenicity of the pathogen in cotton.,H Ren 2022,2022,4 genes,"Ren-2022-Loss of function of VdDrs2, a P4-ATPa",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20886,PHI:123513,UniProt,G2X9B1,GenBank,EGY15579,,,VdLs.17,VdDnf1 (VDAG_06743),chromosome 8,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,seedling,26S proteasome regulatory subunit RPN2,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,36072318,PubMed,10.3389/fpls.2022.944364,Front Plant Sci. 2022 Aug 22;13:944364,peiyan3@swu.edu.cn,Loss of function of VdDnf1 significantly decreased the pathogenicity of the pathogen in cotton.,H Ren 2022,2022,4 genes,"Ren-2022-Loss of function of VdDrs2, a P4-ATPa",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20887,PHI:123514,UniProt,Q8Y2A2,GenBank,CAD13962,,,GMI1000,AcpP2 (RSc0434),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,,putative acyl carrier protein-like,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36212838,PubMed,10.3389/fmicb.2022.1014971,Front Microbiol. 2022 Sep 23;13:1014971,wanghh36@scau.edu.cn,Single gene R. solanacearum mutants lacking acpP2 did not affect the pathogenicity of R. solanacearum.,Y Yin 2022,2022,4 genes,"Yin-2022-Of its five acyl carrier proteins, on",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20888,PHI:123515,UniProt,Q8XPI1,GenBank,CAD18810,,,GMI1000,AcpP3 (RSp1659),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,,acyl carrier protein 3,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36212838,PubMed,10.3389/fmicb.2022.1014971,Front Microbiol. 2022 Sep 23;13:1014971,wanghh36@scau.edu.cn,Single gene R. solanacearum mutants lacking acpP3 did not affect the pathogenicity of R. solanacearum.,Y Yin 2022,2022,4 genes,"Yin-2022-Of its five acyl carrier proteins, on",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20889,PHI:123516,UniProt,Q8XSU7,GenBank,CAD17521,,,GMI1000,AcpP4 (RSp0370),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,,putative acyl-carrier protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36212838,PubMed,10.3389/fmicb.2022.1014971,Front Microbiol. 2022 Sep 23;13:1014971,wanghh36@scau.edu.cn,Single gene R. solanacearum mutants lacking acpP4 did not affect the pathogenicity of R. solanacearum.,Y Yin 2022,2022,4 genes,"Yin-2022-Of its five acyl carrier proteins, on",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20890,PHI:123517,UniProt,Q8XSU8,GenBank,CAD17520,,,GMI1000,AcpP5 (RSp0369),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,,acyl carrier protein 2,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36212838,PubMed,10.3389/fmicb.2022.1014971,Front Microbiol. 2022 Sep 23;13:1014971,wanghh36@scau.edu.cn,Single gene R. solanacearum mutants lacking acpP5 did not affect the pathogenicity of R. solanacearum.,Y Yin 2022,2022,4 genes,"Yin-2022-Of its five acyl carrier proteins, on",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20891,PHI:123514,UniProt,Q8Y2A2,GenBank,CAD13962,,,GMI1000,AcpP2 (RSc0434),,,,,,PHI:27; PHI:28; PHI:29,305,Ralstonia solanacearum,267608,GMI1000,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,,putative acyl carrier protein-like,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36212838,PubMed,10.3389/fmicb.2022.1014971,Front Microbiol. 2022 Sep 23;13:1014971,wanghh36@scau.edu.cn,"The disruption of four acp genes (acpP2, acpP3, acpP4, and acpP5) allowed the mutant strain to grow as well as the wild-type strain, but attenuated the bacterium's pathogenicity in the host plant tomato.",Y Yin 2022,2022,4 genes,"Yin-2022-Of its five acyl carrier proteins, on",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20892,PHI:123515,UniProt,Q8XPI1,GenBank,CAD18810,,,GMI1000,AcpP3 (RSp1659),,,,,,PHI:26; PHI:28; PHI:29,305,Ralstonia solanacearum,267608,GMI1000,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,,acyl carrier protein 3,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36212838,PubMed,10.3389/fmicb.2022.1014971,Front Microbiol. 2022 Sep 23;13:1014971,wanghh36@scau.edu.cn,"The disruption of four acp genes (acpP2, acpP3, acpP4, and acpP5) allowed the mutant strain to grow as well as the wild-type strain, but attenuated the bacterium's pathogenicity in the host plant tomato.",Y Yin 2022,2022,4 genes,"Yin-2022-Of its five acyl carrier proteins, on",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20893,PHI:123516,UniProt,Q8XSU7,GenBank,CAD17521,,,GMI1000,AcpP4 (RSp0370),,,,,,PHI:26; PHI:27; PHI:29,305,Ralstonia solanacearum,267608,GMI1000,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,,putative acyl-carrier protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36212838,PubMed,10.3389/fmicb.2022.1014971,Front Microbiol. 2022 Sep 23;13:1014971,wanghh36@scau.edu.cn,"The disruption of four acp genes (acpP2, acpP3, acpP4, and acpP5) allowed the mutant strain to grow as well as the wild-type strain, but attenuated the bacterium's pathogenicity in the host plant tomato.",Y Yin 2022,2022,4 genes,"Yin-2022-Of its five acyl carrier proteins, on",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20894,PHI:123517,UniProt,Q8XSU8,GenBank,CAD17520,,,GMI1000,AcpP5 (RSp0369),,,,,,PHI:26; PHI:27; PHI:28,305,Ralstonia solanacearum,267608,GMI1000,wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,,acyl carrier protein 2,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36212838,PubMed,10.3389/fmicb.2022.1014971,Front Microbiol. 2022 Sep 23;13:1014971,wanghh36@scau.edu.cn,"The disruption of four acp genes (acpP2, acpP3, acpP4, and acpP5) allowed the mutant strain to grow as well as the wild-type strain, but attenuated the bacterium's pathogenicity in the host plant tomato.",Y Yin 2022,2022,4 genes,"Yin-2022-Of its five acyl carrier proteins, on",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20895,PHI:123518,UniProt,J5JD79,GenBank,EJP61741,,,ARSEF 2860,BbAMP2 (BBA_09303),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,flies,7227,Drosophila melanogaster (related: fruit fly),W1118,,,larva,INVERT_DEFENSINS domain-containing protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36127432,PubMed,10.1038/s41396-022-01323-7,ISME J. 2022 Sep 20,wangcs@sippe.ac.cn,Deletion of BbAMP2 did not affect insect survivals compared with the WT strain.,S Hong 2022,2022,4 genes,Hong-2022-Suppression of the insect cuticular,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20896,PHI:123519,UniProt,J4KLM1,GenBank,EJP62444,,,ARSEF 2860,BbAMP3 (BBA_08528),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,flies,7227,Drosophila melanogaster (related: fruit fly),W1118,,,larva,antifungal protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36127432,PubMed,10.1038/s41396-022-01323-7,ISME J. 2022 Sep 20,wangcs@sippe.ac.cn,Deletion of BbAMP3 did not affect insect survivals compared with the WT strain.,S Hong 2022,2022,4 genes,Hong-2022-Suppression of the insect cuticular,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20897,PHI:123520,UniProt,J4VU46,GenBank,EJP62050,,,ARSEF 2860,BbAMP4 (BBA_08974),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,flies,7227,Drosophila melanogaster (related: fruit fly),W1118,,,larva,antifungal protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36127432,PubMed,10.1038/s41396-022-01323-7,ISME J. 2022 Sep 20,wangcs@sippe.ac.cn,Deletion of BbAMP3 did not affect insect survivals compared with the WT strain.,S Hong 2022,2022,4 genes,Hong-2022-Suppression of the insect cuticular,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20898,PHI:123521,UniProt,J4WFQ6,GenBank,EJP68750,,,ARSEF 2860,BbAMP1 (BBA_01785),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,flies,7227,Drosophila melanogaster (related: fruit fly),W1118,,,larva,defensin domain protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36127432,PubMed,10.1038/s41396-022-01323-7,ISME J. 2022 Sep 20,wangcs@sippe.ac.cn,Approximately 18% increase of fly survival time was seen for the treatment with ΔBbAMP1 compared with that of the WT.,S Hong 2022,2022,4 genes,Hong-2022-Suppression of the insect cuticular,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20899,PHI:123521,UniProt,J4WFQ6,GenBank,EJP68750,,,ARSEF 2860,BbAMP1 (BBA_01785),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,flies,7227,Drosophila melanogaster (related: fruit fly),W1118,,,larva,defensin domain protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36127432,PubMed,10.1038/s41396-022-01323-7,ISME J. 2022 Sep 20,wangcs@sippe.ac.cn,Overexpresseion of BbAMP1 reduced fly survival times by 30% compared with that of the WT.,S Hong 2022,2022,4 genes,Hong-2022-Suppression of the insect cuticular,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20900,PHI:123521,UniProt,J4WFQ6,GenBank,EJP68750,,,ARSEF 2860,BbAMP1 (BBA_01785),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,defensin domain protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36127432,PubMed,10.1038/s41396-022-01323-7,ISME J. 2022 Sep 20,wangcs@sippe.ac.cn,Increase of survival time was seen for the treatment with ΔBbAMP1 compared with that of the WT.,S Hong 2022,2022,4 genes,Hong-2022-Suppression of the insect cuticular,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20901,PHI:123521,UniProt,J4WFQ6,GenBank,EJP68750,,,ARSEF 2860,BbAMP1 (BBA_01785),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,defensin domain protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36127432,PubMed,10.1038/s41396-022-01323-7,ISME J. 2022 Sep 20,wangcs@sippe.ac.cn,Overexpresseion of BbAMP1 reduced survival times compared with that of the WT.,S Hong 2022,2022,4 genes,Hong-2022-Suppression of the insect cuticular,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20902,PHI:123522,UniProt,W7M0U9,GenBank,EWG45208,,,7600,FvPex7 (FVEG_06097),chromosome 2,,,FvPex20 (FVEG_03840),UniProt: W7M2N6; GenBank: EWG41835,,117187,Fusarium verticillioides,,FGSC 7600,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,stem,peroxin-7,,,,reduced virulence,,,,,,reduced,,wild type,,no,Congo red; calcofluor white; SDS,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,36121485,PubMed,10.1007/s00253-022-12167-8,Appl Microbiol Biotechnol. 2022 Oct;106(19-20):6595-6609,wangzh@fafu.edu,The deletion of FvPex7 showed reduced conidiation and pathogenicity.,M Lin 2022,2022,3 genes,Lin-2022-Fusarium verticillioides Pex7_20 medi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20903,PHI:123523,UniProt,W7M2N6,GenBank,EWG41835,,,7600,FvPex20 (FVEG_03840),chromosome 2,,,FvPex7 (FVEG_06097),UniProt: W7M0U9; GenBank: EWG45208,,117187,Fusarium verticillioides,,FGSC 7600,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,stem,peroxin-20,,,,reduced virulence,,,,,,reduced,,wild type,,no,Congo red; calcofluor white; SDS,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,36121485,PubMed,10.1007/s00253-022-12167-8,Appl Microbiol Biotechnol. 2022 Oct;106(19-20):6595-6609,wangzh@fafu.edu,The deletion of FvPex20 showed reduced conidiation and pathogenicity.,M Lin 2022,2022,3 genes,Lin-2022-Fusarium verticillioides Pex7_20 medi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20904,PHI:123522,UniProt,W7M0U9,GenBank,EWG45208,,,7600,FvPex7 (FVEG_06097),chromosome 2,,,,,PHI:123523,117187,Fusarium verticillioides,,FGSC 7600,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,stem,peroxin-7,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; SDS,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full,,,NN,36121485,PubMed,10.1007/s00253-022-12167-8,Appl Microbiol Biotechnol. 2022 Oct;106(19-20):6595-6609,wangzh@fafu.edu,The deletion of FvPex7Pex20 showed reduced conidiation and pathogenicity.,M Lin 2022,2022,3 genes,Lin-2022-Fusarium verticillioides Pex7_20 medi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20905,PHI:123523,UniProt,W7M2N6,GenBank,EWG41835,,,7600,FvPex20 (FVEG_03840),chromosome 2,,,,,PHI:123522,117187,Fusarium verticillioides,,FGSC 7600,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,stem,peroxin-20,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; SDS,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full,,,NN,36121485,PubMed,10.1007/s00253-022-12167-8,Appl Microbiol Biotechnol. 2022 Oct;106(19-20):6595-6609,wangzh@fafu.edu,The deletion of FvPex7Pex20 showed reduced conidiation and pathogenicity.,M Lin 2022,2022,3 genes,Lin-2022-Fusarium verticillioides Pex7_20 medi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20906,PHI:123522,UniProt,W7M0U9,GenBank,EWG45208,,,7600,FvPex7 (FVEG_06097),chromosome 2,,,,,PHI:123524,117187,Fusarium verticillioides,,FGSC 7600,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,stem,peroxin-7,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; SDS,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full,,,NN,36121485,PubMed,10.1007/s00253-022-12167-8,Appl Microbiol Biotechnol. 2022 Oct;106(19-20):6595-6609,wangzh@fafu.edu,The deletion of FvPex7Pex5 showed reduced conidiation and pathogenicity.,M Lin 2022,2022,3 genes,Lin-2022-Fusarium verticillioides Pex7_20 medi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20907,PHI:123524,UniProt,W7LED9,GenBank,EWG37853,,,7600,FvPex5,chromosome 1,,,,,PHI:123522,117187,Fusarium verticillioides,,FGSC 7600,ear rot (maize),monocots,4577,Zea mays (related: maize),B73 line,,,stem,peroxin-20,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; calcofluor white; SDS,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984,,,,,gene deletion: full,,,NN,36121485,PubMed,10.1007/s00253-022-12167-8,Appl Microbiol Biotechnol. 2022 Oct;106(19-20):6595-6609,wangzh@fafu.edu,The deletion of FvPex7Pex5 showed reduced conidiation and pathogenicity.,M Lin 2022,2022,3 genes,Lin-2022-Fusarium verticillioides Pex7_20 medi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20908,PHI:123525,UniProt,A0A719CV62,GenBank,HAD6865018,,,SL1344,ompV,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver; intestine,MipA/OmpV family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,32017350,PubMed,10.1111/cmi.13172,Cell Microbiol. 2020 May;22(5):e13172,arunika@iisermohali.ac.in,"Lack of ompV resulted in reduced bacteria in the stools, liver, spleen and intestine of Δompv-infected mice indicating reduced virulence in a mouse model of infection.",D Kaur 2020,2020,1 gene,Kaur-2020-Outer membrane protein OmpV mediates,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20909,PHI:123525,UniProt,A0A719CV62,GenBank,HAD6865018,,,SL1344,ompV,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,epithelial cell,MipA/OmpV family protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,32017350,PubMed,10.1111/cmi.13172,Cell Microbiol. 2020 May;22(5):e13172,arunika@iisermohali.ac.in,"A significant decrease in the number of S. typhimurium was observed inside the Caco-2 cells upon deletion of ompV, as compared with those with the wild type and the complemented strains.",D Kaur 2020,2020,1 gene,Kaur-2020-Outer membrane protein OmpV mediates,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20910,PHI:123526,UniProt,J4WH14,GenBank,EJP69175,,,ARSEF 2860,Fpr1 (EJP69175),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,peptidylprolyl isomerase,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; KCl; sorbitol; hydrogen peroxide; menadione; Congo red; SDS; calcofluor white,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:17924; hydrogen peroxide: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,32602171,PubMed,10.1111/cmi.13239,Cell Microbiol. 2020 Oct;22(10):e13239,mgfeng@zju.edu.cn,"Radial growth, conidiation, conidial viability and virulence were compromised in the absence of fpr1.",A-Z Mouhoumed 2020,2020,3 genes,Mouhoumed-2020-Three proline rotamases involve,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20911,PHI:123527,UniProt,J5K9F1,GenBank,EJP70756,,,ARSEF 2860,Fpr2 (EJP70756),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,peptidylprolyl isomerase,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; KCl; sorbitol; hydrogen peroxide; menadione; Congo red; SDS; calcofluor white,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:17924; hydrogen peroxide: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,32602171,PubMed,10.1111/cmi.13239,Cell Microbiol. 2020 Oct;22(10):e13239,mgfeng@zju.edu.cn,"Radial growth, conidiation, conidial viability and virulence were compromised in the absence of fpr2.",A-Z Mouhoumed 2020,2020,3 genes,Mouhoumed-2020-Three proline rotamases involve,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20912,PHI:123528,UniProt,J4KR90,GenBank,EJP70539,,,ARSEF 2860,Fpr3 (EJP70539),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,peptidylprolyl isomerase,,,,reduced virulence,,,,,,reduced,,reduced,,no,NaCl; KCl; sorbitol; hydrogen peroxide; menadione; Congo red; SDS; calcofluor white,NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:17924; hydrogen peroxide: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,32602171,PubMed,10.1111/cmi.13239,Cell Microbiol. 2020 Oct;22(10):e13239,mgfeng@zju.edu.cn,"Radial growth, conidiation, conidial viability and virulence were compromised in the absence of fpr3.",A-Z Mouhoumed 2020,2020,3 genes,Mouhoumed-2020-Three proline rotamases involve,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20913,PHI:123529,UniProt,Q5ACW8,GenBank,AOW27087,,,SC5314,Hir1,chromosome 2,,,,,,5476,Candida albicans,,,candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,spleen; liver; lung; kidney; tongue,histone chaperone,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,gene deletion: full,,,NN,34289370,PubMed,10.1016/j.celrep.2021.109406,Cell Rep. 2021 Jul 20;36(3):109406,karl.kuchler@meduniwien.ac.at,"Mice intravenously infected with the hir1Δ/Δ mutant showed a dramatic decrease in survival, as also reflected by accelerated loss of body weight when compared to the WT",S Jenull 2021,2021,1 gene,Jenull-2021-The histone chaperone HIR maintain,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20914,PHI:123530,UniProt,A0A1D8PGZ5,GenBank,AOW27388,,,SC5314,Rad30,chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,kidney,histone chaperone,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,31424154,PubMed,10.1111/cmi.13103,Cell Microbiol. 2019 Dec;21(12):e13103,doureradjou@ils.res.in,Rad30Δ cells appeared to be more virulent in host C57BL/6J mice strain.,D Peroumal 2019,2019,1 gene,Peroumal-2019-Virulence and pathogenicity of a,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20915,PHI:123530,UniProt,A0A1D8PGZ5,GenBank,AOW27388,,,SC5314,Rad30,chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,histone chaperone,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,31424154,PubMed,10.1111/cmi.13103,Cell Microbiol. 2019 Dec;21(12):e13103,doureradjou@ils.res.in,Both the wild-type and Rad30Δ mutant strains of C. albicans appeared equally virulent in BALB/c mice.,D Peroumal 2019,2019,1 gene,Peroumal-2019-Virulence and pathogenicity of a,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20916,PHI:123531,,no data found,GenBank,MW841611,,,LT263,PcEXLX1 (MW841611),,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,expansin-like protein,,,,increased virulence (hypervirulence),,,,,large lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,34825772,PubMed,10.1111/jipb.13194,J Integr Plant Biol. 2022 Jan;64(1):183-201,ddou@cau.edu.cn,The knockout transformants of PcEXLX1 showed caused larger lesions and increased virulence.,L Pi 2022,2022,1 gene,Pi-2022-A G-type lectin receptor-like kinase r,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20917,PHI:123531,,no data found,GenBank,MW841611,,,LT263,PcEXLX1 (MW841611),,,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,expansin-like protein,,,,reduced virulence,,,,,smaller lesions,,,increased,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,34825772,PubMed,10.1111/jipb.13194,J Integr Plant Biol. 2022 Jan;64(1):183-201,ddou@cau.edu.cn,The overexpression of PcEXLX1 showed caused smaller lesions and decreased virulence.,L Pi 2022,2022,1 gene,Pi-2022-A G-type lectin receptor-like kinase r,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20918,PHI:123532,UniProt,Q8ZND1,GenBank,AAL21246,,,LT2,pagR (STM2345),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,31610610,PubMed,10.1111/cmi.13125,Cell Microbiol. 2020 Feb;22(2):e13125,liubin1981@nankai.edu.cn,Loss of pagR significantly decreased bacterial replication in RAW264.7 cells,L Jiang 2020,2020,4 genes,Jiang-2019-PagR mediates the precise regulatio,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20919,PHI:123532,UniProt,Q8ZND1,GenBank,AAL21246,,,LT2,pagR (STM2345),,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal macrophage; ileum; liver; spleen,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,31610610,PubMed,10.1111/cmi.13125,Cell Microbiol. 2020 Feb;22(2):e13125,liubin1981@nankai.edu.cn,"Loss of pagR significantly decreased bacterial replication in BALB/c peritoneal macrophages. All mice infected with the WT strain died within 7 days, whereas 37% of the mice infected with the pagR mutant survived.",L Jiang 2020,2020,4 genes,Jiang-2019-PagR mediates the precise regulatio,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20920,PHI:123533,UniProt,A0A0F6B0Y6,GenBank,ACY88164,,,14028S,ssrB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,31610610,PubMed,10.1111/cmi.13125,Cell Microbiol. 2020 Feb;22(2):e13125,liubin1981@nankai.edu.cn,Loss of ssrB significantly decreased virulence in mouse model of infection.,L Jiang 2020,2020,4 genes,Jiang-2019-PagR mediates the precise regulatio,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20921,PHI:123532,UniProt,Q8ZND1,GenBank,AAL21246,,,LT2,pagR (STM2345),,,,,,PHI:123533,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,31610610,PubMed,10.1111/cmi.13125,Cell Microbiol. 2020 Feb;22(2):e13125,liubin1981@nankai.edu.cn,pagR/ssrB double mutant significantly decreased virulence in mouse model of infection.,L Jiang 2020,2020,4 genes,Jiang-2019-PagR mediates the precise regulatio,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20922,PHI:123533,UniProt,A0A0F6B0Y6,GenBank,ACY88164,,,14028S,ssrB,,,,,,PHI:123532,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,31610610,PubMed,10.1111/cmi.13125,Cell Microbiol. 2020 Feb;22(2):e13125,liubin1981@nankai.edu.cn,pagR/ssrB double mutant significantly decreased virulence in mouse model of infection.,L Jiang 2020,2020,4 genes,Jiang-2019-PagR mediates the precise regulatio,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20923,PHI:123534,UniProt,Q7CR43,GenBank,AAL19351,,,LT2,phoB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,31610610,PubMed,10.1111/cmi.13125,Cell Microbiol. 2020 Feb;22(2):e13125,liubin1981@nankai.edu.cn,Loss of phoB significantly decreased bacterial replication in RAW264.7 cells,L Jiang 2020,2020,4 genes,Jiang-2019-PagR mediates the precise regulatio,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20924,PHI:123534,UniProt,Q7CR43,GenBank,AAL19351,,,LT2,phoB,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,31610610,PubMed,10.1111/cmi.13125,Cell Microbiol. 2020 Feb;22(2):e13125,liubin1981@nankai.edu.cn,Loss of phoB significantly decreased virulence in mouse model of infection.,L Jiang 2020,2020,4 genes,Jiang-2019-PagR mediates the precise regulatio,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20925,PHI:123535,UniProt,D0ZV90,GenBank,ACY87895,,,LT2,phoP,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,infection,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,virulence transcriptional regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,31610610,PubMed,10.1111/cmi.13125,Cell Microbiol. 2020 Feb;22(2):e13125,liubin1981@nankai.edu.cn,Loss of phoP significantly decreased bacterial replication in RAW264.7 cells,L Jiang 2020,2020,4 genes,Jiang-2019-PagR mediates the precise regulatio,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20926,PHI:123536,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,PopP2,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,,acetyltransferase effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; functional test in host: transient expression,,,NN,34978271,PubMed,10.1080/15592324.2021.2017631,Plant Signal Behav. 2021 Dec 2;16(12):2017631,sungun@kunsan.ac.k,PopP2 effector targets both immune regulator EDS1 and PAD4 to suppress plant immunity.,S U Huh 2021,2021,1 gene,Huh-2021-PopP2 interacts with PAD4 in an acety,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20927,PHI:123536,UniProt,Q8Y125,GenBank,CAD14570,,,GMI1000,PopP2,,C321A,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,acetyltransferase effector,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation: characterised; functional test in host: transient expression,,,NN,34978271,PubMed,10.1080/15592324.2021.2017631,Plant Signal Behav. 2021 Dec 2;16(12):2017631,sungun@kunsan.ac.k,Arabidopsis PAD4 lipase-like domain protein physically associates with enzymatic active PopP2 protein but not inactive PopP2 C321A when transiently co-expressed in N. benthamiana.,S U Huh 2021,2021,1 gene,Huh-2021-PopP2 interacts with PAD4 in an acety,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20928,PHI:123537,UniProt,J5J6H7,GenBank,EJP62113,,,ARSEF 2860,BbAcs1 (EJP62113),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,acetyl-coenzyme A synthetase,,,,unaffected pathogenicity,,,,,,reduced,,defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36175799,PubMed,10.1007/s00203-022-03269-y,Arch Microbiol. 2022 Sep 29;204(10):653,yingsh@zju.edu.cn,Deletion of BbAcs1 caused reduction in conidial yield but did not affect virulence.,J-H Lei 2022,2022,2 genes,Lei-2022-Functional characterization of two ho,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20929,PHI:123538,UniProt,J5JLJ4,GenBank,EJP66218,,,ARSEF 2860,BbAcs2 (EJP66218),unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,acetyl-coenzyme A synthetase,,,,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36175799,PubMed,10.1007/s00203-022-03269-y,Arch Microbiol. 2022 Sep 29;204(10):653,yingsh@zju.edu.cn,Deletion of BbAcs2 caused reduction in blastophore production and virulence.,J-H Lei 2022,2022,2 genes,Lei-2022-Functional characterization of two ho,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20930,PHI:123539,UniProt,A0A8E5HY10,GenBank,QUC23621,,,UV-8b,UvSte50 (UV8b_07862),chromosome 7,,,"UvSte7 (UV8b_04866); UvSte11 (UV8b_06470); UvHog1 (UV8b_04241); UvAc1 (UV8b_02467); UvCap1 (UV8b_00969); peroxisomal biogenesis factor 6 (UV8b_06597), GTPaseactivating protein (Gyp2;UV8b_04168), cAMP-dependent protein kinase regulatory subunit (UV8b_04860); regulator of G protein signaling pathway (UV8b_04229)",UniProt: A0A063BTN4; GenBank: QUC20625; UniProt: A0A8E5HVY3; GenBank: QUC22229; UniProt: A0A,,1159556,Ustilaginoidea virens,,Jt209,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Liangyoupeijiu,,,spikelet,MAP kinase,,,MAPK pathway,loss of pathogenicity,,,,,,reduced,,wild type,wild type,no,NaCl; sorbitol; calcofluor white; Congo red; SDS; H2O2,NaCl: CHEBI:26710; sorbitol: CHEBI:30911; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36135679,PubMed,10.3390/jof8090954,J Fungi (Basel). 2022 Sep 11;8(9):954,liuyf@jaas.ac.cn,"ΔUvste50 was found to be defective in conidiation, sensitive to hyperosmotic and oxidative stresses, and non-pathogenic.",H Cao 2022,2022,1 gene,Cao-2022-The Adaptor Protein UvSte50 Governs F,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20931,PHI:123540,UniProt,A0A384K6A7,GenBank,ATZ58302,,,B05.10,PEX8 (BCIN_16g01260),chromosome BCIN16,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,peroxisomal membrane protein,,,,loss of pathogenicity,,,,,,reduced,,reduced; defective,reduced,no,NaCl; calcofluor white; Congo red; H2O2; fludioxonil; KCl,NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; fludioxonil: CHEBI:81763; KCl: CHEBI:32588,,,,,gene deletion: full,,,NN,36147853,PubMed,10.3389/fmicb.2022.962500,Front Microbiol. 2022 Sep 6;13:962500,wangjiaoyu78@sina.com,"The mycelial growth and conidiation of were significantly inhibited in Δbcpex8 strain. On the leaves of tobacco and strawberry, the Δbcpex8 mutant could not induce necrotic lesion.",L Li 2022,2022,3 genes,"Li-2022-The peroxins BcPex8, BcPex10, and BcPe",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20932,PHI:123540,UniProt,A0A384K6A7,GenBank,ATZ58302,,,B05.10,PEX8 (BCIN_16g01260),chromosome BCIN16,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,peroxisomal membrane protein,,,,loss of pathogenicity,,,,,,reduced,,reduced; defective,reduced,no,NaCl; calcofluor white; Congo red; H2O2; fludioxonil; KCl,NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; fludioxonil: CHEBI:81763; KCl: CHEBI:32588,,,,,gene deletion: full,,,NN,36147853,PubMed,10.3389/fmicb.2022.962500,Front Microbiol. 2022 Sep 6;13:962500,wangjiaoyu78@sina.com,"The mycelial growth and conidiation of were significantly inhibited in Δbcpex8 strain. On the leaves of tobacco and strawberry, the Δbcpex8 mutant could not induce necrotic lesion.",L Li 2022,2022,3 genes,"Li-2022-The peroxins BcPex8, BcPex10, and BcPe",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20933,PHI:123540,UniProt,A0A384K6A7,GenBank,ATZ58302,,,B05.10,PEX8 (BCIN_16g01260),chromosome BCIN16,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,peroxisomal membrane protein,,,,reduced virulence,,,,,smaller lesion,reduced,,reduced; defective,reduced,no,NaCl; calcofluor white; Congo red; H2O2; fludioxonil; KCl,NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; fludioxonil: CHEBI:81763; KCl: CHEBI:32588,,,,,gene deletion: full,,,NN,36147853,PubMed,10.3389/fmicb.2022.962500,Front Microbiol. 2022 Sep 6;13:962500,wangjiaoyu78@sina.com,The mycelial growth and conidiation of were significantly inhibited in Δbcpex8 strain. The Δbcpex8 mutant caused smaller lesions on tomato fruit compared to wild-type.,L Li 2022,2022,3 genes,"Li-2022-The peroxins BcPex8, BcPex10, and BcPe",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20934,PHI:123541,UniProt,A0A384J4R7,GenBank,ATZ45505,,,B05.10,PEX10 (BCIN_01g02750),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,peroxisomal membrane protein,,,,loss of pathogenicity,,,,,,reduced,,reduced; defective,reduced,no,NaCl; calcofluor white; Congo red; H2O2; fludioxonil; KCl,NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; fludioxonil: CHEBI:81763; KCl: CHEBI:32588,,,,,gene deletion: full,,,NN,36147853,PubMed,10.3389/fmicb.2022.962500,Front Microbiol. 2022 Sep 6;13:962500,wangjiaoyu78@sina.com,"The mycelial growth and conidiation of were significantly inhibited in Δbcpex10 strain. On the leaves of tobacco and strawberry, the Δbcpex10 mutant could not induce necrotic lesion.",L Li 2022,2022,3 genes,"Li-2022-The peroxins BcPex8, BcPex10, and BcPe",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20935,PHI:123541,UniProt,A0A384J4R7,GenBank,ATZ45505,,,B05.10,PEX10 (BCIN_01g02750),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,peroxisomal membrane protein,,,,loss of pathogenicity,,,,,,reduced,,reduced; defective,reduced,no,NaCl; calcofluor white; Congo red; H2O2; fludioxonil; KCl,NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; fludioxonil: CHEBI:81763; KCl: CHEBI:32588,,,,,gene deletion: full,,,NN,36147853,PubMed,10.3389/fmicb.2022.962500,Front Microbiol. 2022 Sep 6;13:962500,wangjiaoyu78@sina.com,"The mycelial growth and conidiation of were significantly inhibited in Δbcpex10 strain. On the leaves of tobacco and strawberry, the Δbcpex10 mutant could not induce necrotic lesion.",L Li 2022,2022,3 genes,"Li-2022-The peroxins BcPex8, BcPex10, and BcPe",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20936,PHI:123541,UniProt,A0A384J4R7,GenBank,ATZ45505,,,B05.10,PEX10 (BCIN_01g02750),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,peroxisomal membrane protein,,,,reduced virulence,,,,,smaller lesion,reduced,,reduced; defective,reduced,no,NaCl; calcofluor white; Congo red; H2O2; fludioxonil; KCl,NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; fludioxonil: CHEBI:81763; KCl: CHEBI:32588,,,,,gene deletion: full,,,NN,36147853,PubMed,10.3389/fmicb.2022.962500,Front Microbiol. 2022 Sep 6;13:962500,wangjiaoyu78@sina.com,The mycelial growth and conidiation of were significantly inhibited in Δbcpex10 strain. The Δbcpex10 mutant caused smaller lesions on tomato fruit compared to wild-type.,L Li 2022,2022,3 genes,"Li-2022-The peroxins BcPex8, BcPex10, and BcPe",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20937,PHI:123542,UniProt,A0A384K000,GenBank,ATZ56091,,,B05.10,PEX12 (BCIN_12g06240),chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,peroxisomal membrane protein,,,,loss of pathogenicity,,,,,,reduced,,reduced; defective,reduced,no,NaCl; calcofluor white; Congo red; H2O2; fludioxonil; KCl,NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; fludioxonil: CHEBI:81763; KCl: CHEBI:32588,,,,,gene deletion: full,,,NN,36147853,PubMed,10.3389/fmicb.2022.962500,Front Microbiol. 2022 Sep 6;13:962500,wangjiaoyu78@sina.com,"The mycelial growth and conidiation of were significantly inhibited in Δbcpex12 strain. On the leaves of tobacco and strawberry, the Δbcpex12 mutant could not induce necrotic lesion.",L Li 2022,2022,3 genes,"Li-2022-The peroxins BcPex8, BcPex10, and BcPe",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20938,PHI:123542,UniProt,A0A384K000,GenBank,ATZ56091,,,B05.10,PEX12 (BCIN_12g06240),chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,peroxisomal membrane protein,,,,loss of pathogenicity,,,,,,reduced,,reduced; defective,reduced,no,NaCl; calcofluor white; Congo red; H2O2; fludioxonil; KCl,NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; fludioxonil: CHEBI:81763; KCl: CHEBI:32588,,,,,gene deletion: full,,,NN,36147853,PubMed,10.3389/fmicb.2022.962500,Front Microbiol. 2022 Sep 6;13:962500,wangjiaoyu78@sina.com,"The mycelial growth and conidiation of were significantly inhibited in Δbcpex12 strain. On the leaves of tobacco and strawberry, the Δbcpex12 mutant could not induce necrotic lesion.",L Li 2022,2022,3 genes,"Li-2022-The peroxins BcPex8, BcPex10, and BcPe",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20939,PHI:123542,UniProt,A0A384K000,GenBank,ATZ56091,,,B05.10,PEX12 (BCIN_12g06240),chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,peroxisomal membrane protein,,,,reduced virulence,,,,,smaller lesion,reduced,,reduced; defective,reduced,no,NaCl; calcofluor white; Congo red; H2O2; fludioxonil; KCl,NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011; Congo red: CHEBI:34653; H2O2: CHEBI:16240; fludioxonil: CHEBI:81763; KCl: CHEBI:32588,,,,,gene deletion: full,,,NN,36147853,PubMed,10.3389/fmicb.2022.962500,Front Microbiol. 2022 Sep 6;13:962500,wangjiaoyu78@sina.com,The mycelial growth and conidiation of were significantly inhibited in Δbcpex12 strain. The Δbcpex12 mutant caused smaller lesions on tomato fruit compared to wild-type.,L Li 2022,2022,3 genes,"Li-2022-The peroxins BcPex8, BcPex10, and BcPe",BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20940,PHI:123543,UniProt,A0A098DRQ4,GenBank,CEF84540,,,PH-1,FgATG20 (FGSG_06950),chromosome 4,,,FgAtg24; FgAtg17; FgAtg11,UniProt: I1RXT2; GenBank: CEF84195; UniProt: I1RR07; GenBank: SCB65064; UniProt: A0A098D065;,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 33,,,spikelet,sorting nexin protein,,,,reduced virulence,,,,,,reduced,wild type,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,32281734,PubMed,10.1111/cmi.13208,Cell Microbiol. 2020 Aug;22(8):e13208,zhywang@zju.edu.cn,The FgATG201 deletion mutant affected vegetative growth of the fungus and also significantly impaired the spread of the fungus in host tissue and disease symptom development.,W Lv 2020,2020,1 gene,Lv-2020-The sorting nexin FgAtg20 is involved,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20941,PHI:123544,UniProt,A0A5B0MRS6,GenBank,KAA1079665,,,,AvrSr50,,,,,,,5297,Puccinia graminis,,f. sp. tritici,stem rust,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,35107838,PubMed,10.1111/nph.18011,New Phytol. 2022 Apr;234(2):592-606,simon.williams@anu.edu.au,"AvrSr50 can escape recognition by Sr50 through different mechanisms including DNA insertion, stop codon loss or by amino-acid variation involving a single substitution of the AvrSr50 surface-exposed residue Q121.",D Ortiz 2022,2022,1 gene,Ortiz-2022-The stem rust effector protein AvrS,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20942,PHI:123544,UniProt,A0A5B0MRS6,GenBank,KAA1079665,,,,AvrSr50,,,,,,,5297,Puccinia graminis,,f. sp. tritici,stem rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Fielder,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,35107838,PubMed,10.1111/nph.18011,New Phytol. 2022 Apr;234(2):592-606,simon.williams@anu.edu.au,"AvrSr50 can escape recognition by Sr50 through different mechanisms including DNA insertion, stop codon loss or by amino-acid variation involving a single substitution of the AvrSr50 surface-exposed residue Q121.",D Ortiz 2022,2022,1 gene,Ortiz-2022-The stem rust effector protein AvrS,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20943,PHI:123545,UniProt,F9XAU1,GenBank,EGP87059,,,IPO323,Mycgr3G104383,chromosome 5,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Pehlivan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36097116,PubMed,10.1007/s11033-022-07879-z,Mol Biol Rep. 2022 Sep 12,zemran.mustafa@sivas.edu.tr,Mycgr3G104383 knock-out mutant did not show any signifcant diferences in phenotype and virulence compared to wild-type.,Z Mustafa 2022,2022,3 genes,Mustafa-2022-Inactivation of a candidate effec,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20944,PHI:123546,UniProt,F9XKL2,GenBank,EGP84215,,,IPO323,Mycgr3G105826,chromosome 10,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Pehlivan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36097116,PubMed,10.1007/s11033-022-07879-z,Mol Biol Rep. 2022 Sep 12,zemran.mustafa@sivas.edu.tr,Mycgr3G105826 knock-out mutant did not show any signifcant diferences in phenotype and virulence compared to wild-type.,Z Mustafa 2022,2022,3 genes,Mustafa-2022-Inactivation of a candidate effec,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20945,PHI:123547,UniProt,F9XBP2,GenBank,EGP87656,,,IPO323,Mycgr3G104444,chromosome 5,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Pehlivan,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,defective,,reduced,,no,,,,,,,gene deletion: full,,,NN,36097116,PubMed,10.1007/s11033-022-07879-z,Mol Biol Rep. 2022 Sep 12,zemran.mustafa@sivas.edu.tr,"Mycgr3G104444 knock-out mutant did not show any signifcant diferences in virulence compared to wild-type. The mutant generated exclusively macropycnidiospores in artifcial media, diferent from wild-type IPO323 which produce only micropycidiospores. Mycelial growth was also severely attenuated.",Z Mustafa 2022,2022,3 genes,Mustafa-2022-Inactivation of a candidate effec,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20946,PHI:123548,UniProt,G4MSA2,GenBank,EHA58360,,,70-15,MoAde8 (MGG_13813),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,phosphoribosylglycinamide formyltransferase,,,,reduced virulence,,,yes,yes,slight lesions,reduced,,defective,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36135640,PubMed,10.3390/jof8090915,J Fungi (Basel). 2022 Aug 29;8(9):915,xhliu@zju.edu.cn,"The mutant Moade8 exhibited purine auxotroph, defects in aerial hyphal growth, conidiation, and pathogenicity,",M-Y Liu 2022,2022,4 genes,Liu-2022-De Novo Purine Nucleotide Biosynthesi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20947,PHI:123548,UniProt,G4MSA2,GenBank,EHA58360,,,70-15,MoAde8 (MGG_13813),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,phosphoribosylglycinamide formyltransferase,,,,reduced virulence,,,yes,yes,slight lesions,reduced,,defective,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36135640,PubMed,10.3390/jof8090915,J Fungi (Basel). 2022 Aug 29;8(9):915,xhliu@zju.edu.cn,"The mutant Moade8 exhibited purine auxotroph, defects in aerial hyphal growth, conidiation, and pathogenicity,",M-Y Liu 2022,2022,4 genes,Liu-2022-De Novo Purine Nucleotide Biosynthesi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20948,PHI:123549,UniProt,G4MU94,GenBank,EHA53975,,,70-15,"MoAde5,7 (MGG_11343)",chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,phosphoribosylformylglycinamidine cyclo-ligase,,,,reduced virulence,,,,yes,,reduced,,,,no,,,,,,,gene deletion: full,,,NN,36135640,PubMed,10.3390/jof8090915,J Fungi (Basel). 2022 Aug 29;8(9):915,xhliu@zju.edu.cn,"The mutant Moade5,7 exhibited defects in aerial hyphal growth, conidiation, and pathogenicity,",M-Y Liu 2022,2022,4 genes,Liu-2022-De Novo Purine Nucleotide Biosynthesi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20949,PHI:123550,UniProt,G4NB68,GenBank,EHA48830,,,70-15,MoAde6 (MGG_11343),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,phosphoribosylformylglycinamidine synthase,,,,reduced virulence,,,,yes,,reduced,,,,no,,,,,,,gene deletion: full,,,NN,36135640,PubMed,10.3390/jof8090915,J Fungi (Basel). 2022 Aug 29;8(9):915,xhliu@zju.edu.cn,"The mutant Moade6 exhibited defects in aerial hyphal growth, conidiation, and pathogenicity,",M-Y Liu 2022,2022,4 genes,Liu-2022-De Novo Purine Nucleotide Biosynthesi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20950,PHI:123551,UniProt,A4QXV8,GenBank,EHA49567,,,70-15,MoAde12 (MGG_17000),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. ZJ-8,,,leaf,phosphoribosylformylglycinamidine synthase,,,,reduced virulence,,,,yes,,reduced,,,,no,,,,,,,gene deletion: full,,,NN,36135640,PubMed,10.3390/jof8090915,J Fungi (Basel). 2022 Aug 29;8(9):915,xhliu@zju.edu.cn,"The mutant Moade12 exhibited defects in aerial hyphal growth, conidiation, and pathogenicity,",M-Y Liu 2022,2022,4 genes,Liu-2022-De Novo Purine Nucleotide Biosynthesi,BATCH_116A,2022-10-01,MC,,,,,,,,,,,,,
,,Record 20951,PHI:123552,UniProt,B0XS12,GenBank,EDP54498,,,A1163,CcsA (AFUB_025550),,,,"AP-1 adaptor complex subunit beta; Protein transport protein SEC24; Small COPII coat GTPase SAR1; Mitochondrial tricarboxylate transporter (Ctp); Chromosome segregation protein Cse1; Lectin family integral membrane protein; Importin beta-1 subunit; Secretory component protein shr3; RAS small monomeric GTPase RasA; Superoxide dismutase; Thioredoxin, putative; Reticulon-like protein; 60S ribosomal protein L3; Asparagine--tRNA ligase; Alcohol dehydrogenase, putative; Ribosome biogenesis protein C8F11.04; Threonine dehydratase; RNA helicase; PWWP domain protein; Rho_N domain-containing protein; Dynamin GTPase, putative; Vacuolar dynamin-like GTPase VpsA; NADH-ubiquinone oxidoreductase 12 kDa subunit",UniProt: B0XY97; GenBank: EDP52843; UniProt: B0XR47; GenBank: EDP55495; UniProt: B0XNS2; Gen,,746128,Aspergillus fumigatus,,A1161,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,superoxide dismutase 1 copper chaperone,,,,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,34160279,PubMed,10.1128/AEM.01013-21,Appl Environ Microbiol. 2021 Aug 11;87(17):e0101321,ywzhang@njnu.edu.cn,Survival analysis showed that virulence of the ccsA deletion mutant was not significantly altered compared with the parental wild-type strain.,W Du 2022,2022,2 genes,"Du-2021-The Copper Chaperone CcsA, Coupled wit",BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20952,PHI:123553,UniProt,B0Y476,GenBank,EDP51667,,,A1163,sodA (AFUB_056780),,,,ccsA,UniProt: B0XS12; GenBank: EDP54498,,746128,Aspergillus fumigatus,,A1161,invasive pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,superoxide dismutase [Cu-Zn],,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,34160279,PubMed,10.1128/AEM.01013-21,Appl Environ Microbiol. 2021 Aug 11;87(17):e0101321,ywzhang@njnu.edu.cn,Survival analysis showed that virulence of the sodA deletion mutant was not significantly altered compared with the parental wild-type strain.,W Du 2022,2022,2 genes,"Du-2021-The Copper Chaperone CcsA, Coupled wit",BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20953,PHI:123554,UniProt,B1MJN9,GenBank,CAM64396,,,ATCC 19977,GNAT (MAB_4324c),,,,,,,36809,Mycobacteroides abscessus,,,pulmonary infection; cutaneo-mucous infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,35470425,PubMed,10.1002/1873-3468.14360,FEBS Lett. 2022 Jun;596(12):1516-1532,mickael.blaise@irim.cnrs.fr,Overexpression of MAB_4324c N-acetyltransferase enhanced the uptake and survival of M. abscessus in THP-1 macrophages.,H M A B Alsarraf 2022,2022,2 genes,"H-2022-Biochemical, structural, and functional",BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20954,PHI:123554,UniProt,B1MJN9,GenBank,CAM64396,,,ATCC 19977,GNAT (MAB_4324c),,,,,,,36809,Mycobacteroides abscessus,,,pulmonary infection; cutaneo-mucous infection,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,acetyltransferase,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35470425,PubMed,10.1002/1873-3468.14360,FEBS Lett. 2022 Jun;596(12):1516-1532,mickael.blaise@irim.cnrs.fr,Deletion of MAB_4324c N-acetyltransferase did not affect the uptake and survival of M. abscessus in THP-1 macrophages.,H M A B Alsarraf 2022,2022,2 genes,"H-2022-Biochemical, structural, and functional",BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20955,PHI:123555,UniProt,A0A0H2X725,GenBank,AAY49029,,,8004,mcvR,,,,Hlp; HupB; HpaR1; Zur; CheY,UniProt: A0A0H2X5C4; GenBank: AAY48424; UniProt: A0A0H2XBZ2; GenBank: AAY50306; UniProt: A0A,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,two-component system regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35152521,PubMed,10.1111/mpp.13186,Mol Plant Pathol. 2022 May;23(5):649-663,lugt@gxu.edu.cn,"Deletion of the mcvR enhances cell motility, chemotaxis, and virulence.",R F Li 2022,2022,1 gene,"Li-2022-McvR, a single domain response regulat",BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20956,PHI:123555,UniProt,A0A0H2X725,GenBank,AAY49029,,,8004,mcvR,,,,Hlp; HupB; HpaR1; Zur; CheY,UniProt: A0A0H2X5C4; GenBank: AAY48424; UniProt: A0A0H2XBZ2; GenBank: AAY50306; UniProt: A0A,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,leaf,two-component system regulatory protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,35152521,PubMed,10.1111/mpp.13186,Mol Plant Pathol. 2022 May;23(5):649-663,lugt@gxu.edu.cn,"Overexpression of the mcvR open reading frame caused reduced motility, chemotactic movement, and virulence.",R F Li 2022,2022,1 gene,"Li-2022-McvR, a single domain response regulat",BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20957,PHI:123556,UniProt,Q8PDI3,GenBank,AAM39674,,,8004,pobR,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish) cv. Mangshenhong,,,leaf,PobR regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,32757400,PubMed,10.1111/mmi.14585,Mol Microbiol. 2020 Nov;114(5):870-886,yawenhe@sjtu.edu.cn,"The average lesion length of strain ΔpobR in Chinese radish is 12.8 mm, which is significantly shorter than those of wild-type strain.",B Chen 2022,2022,1 gene,Chen-2020-The phytopathogen Xanthomonas campes,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20958,PHI:123556,UniProt,Q8PDI3,GenBank,AAM39674,,,8004,pobR,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,PobR regulator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,32757400,PubMed,10.1111/mmi.14585,Mol Microbiol. 2020 Nov;114(5):870-886,yawenhe@sjtu.edu.cn,"The average lesion length of strain ΔpobR in cabbage is 10 mm, which is significantly shorter than those of wild-type strain.",B Chen 2022,2022,1 gene,Chen-2020-The phytopathogen Xanthomonas campes,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20959,PHI:123557,UniProt,G5EH22,GenBank,EHA46219,,,70-15,PAL1 (MGG_02779),chromosome 7,,,Sla1,UniProt: L7I1B3; GenBank: ELQ36965,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,calcineurin regulator,,,,reduced virulence,,,,,smaller lesion,reduced; defective,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35783935,PubMed,10.1111/mpp.13149,Mol Plant Pathol. 2022 Jan;23(1):133-147,chenxiaolin@mail.hzau.edu.cn,Deletion of PAL1 significantly reduced the virulence of M. oryzaedue to defects in appressorial penetration and invasive growth in host cells.,D Chen 2022,2022,1 gene,Chen-2021-Endocytic protein Pal1 regulates app,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20960,PHI:123557,UniProt,G5EH22,GenBank,EHA46219,,,70-15,PAL1 (MGG_02779),chromosome 7,,,Sla1,UniProt: L7I1B3; GenBank: ELQ36965,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,calcineurin regulator,,,,reduced virulence,,,,,smaller lesion,reduced; defective,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35783935,PubMed,10.1111/mpp.13149,Mol Plant Pathol. 2022 Jan;23(1):133-147,chenxiaolin@mail.hzau.edu.cn,Deletion of PAL1 significantly reduced the virulence of M. oryzaedue to defects in appressorial penetration and invasive growth in host cells.,D Chen 2022,2022,1 gene,Chen-2021-Endocytic protein Pal1 regulates app,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20961,PHI:123558,UniProt,G4N717,GenBank,EHA49930,,,70-15,PAMS1 (MGG_03640),chromosome 4,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,appressorium membrane-specific protein,,,cAMP-PKA signaling pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,36160954,PubMed,10.3389/fpls.2022.955254,Front Plant Sci. 2022 Sep 9;13:955254,jplu@zju.edu.cn,"When sprayed as spore suspensions on rice seedlings, Δpams1 showed significantly reduced virulence as compared to the wild type",J Wang 2022,2022,1 gene,"Wang-2022-An appressorium membrane protein, Pa",BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20962,PHI:123558,UniProt,G4N717,GenBank,EHA49930,,,70-15,PAMS1 (MGG_03640),chromosome 4,,,,,,318829,Magnaporthe oryzae,242507,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,appressorium membrane-specific protein,,,cAMP-PKA signaling pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,36160954,PubMed,10.3389/fpls.2022.955254,Front Plant Sci. 2022 Sep 9;13:955254,jplu@zju.edu.cn,"When inoculated on barley leaves with mycelial blocks, the virulence of Δpams1 was greatly reduced.",J Wang 2022,2022,1 gene,"Wang-2022-An appressorium membrane protein, Pa",BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20963,PHI:123559,UniProt,R9RJ65,GenBank,VTT13358,,,NCTC10446,stk,,Δstk::stkT167A-S175A,,,,,1307,Streptococcus suis,,SC19,meningitis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,serine/threonine kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation: characterised,,,NN,36118193,PubMed,10.3389/fmicb.2022.990091,Front Microbiol. 2022 Sep 2;13:990091,rzhou@mail.hzau.edu.cn,The percentage of survived G. mellonella larvae injected with Δstk::stkT167A-S175A was significantly higher than those injected with SC19 strain.,H li 2022,2022,1 gene,Li-2022-Inhibitors targeting the autophosphory,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20964,PHI:123560,UniProt,A0A384JZT2,GenBank,ATZ56090,,,B05.10,Bcdcl1,BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20965,PHI:123561,UniProt,A0A384K344,GenBank,ATZ57233,,,B05.10,Bcdcl2,BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20966,PHI:123560,UniProt,A0A384JZT2,GenBank,ATZ56090,,,B05.10,Bcdcl1,BCIN12,,,,,PHI:123561,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20967,PHI:123561,UniProt,A0A384K344,GenBank,ATZ57233,,,B05.10,Bcdcl2,BCIN14,,,,,PHI:123560,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20968,PHI:123560,UniProt,A0A384JZT2,GenBank,ATZ56090,,,B05.10,Bcdcl1,BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20969,PHI:123561,UniProt,A0A384K344,GenBank,ATZ57233,,,B05.10,Bcdcl2,BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20970,PHI:123560,UniProt,A0A384JZT2,GenBank,ATZ56090,,,B05.10,Bcdcl1,BCIN12,,,,,PHI:123561,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20971,PHI:123561,UniProt,A0A384K344,GenBank,ATZ57233,,,B05.10,Bcdcl2,BCIN14,,,,,PHI:123560,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20972,PHI:123560,UniProt,A0A384JZT2,GenBank,ATZ56090,,,B05.10,Bcdcl1,BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20973,PHI:123561,UniProt,A0A384K344,GenBank,ATZ57233,,,B05.10,Bcdcl2,BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20974,PHI:123560,UniProt,A0A384JZT2,GenBank,ATZ56090,,,B05.10,Bcdcl1,BCIN12,,,,,PHI:123561,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20975,PHI:123561,UniProt,A0A384K344,GenBank,ATZ57233,,,B05.10,Bcdcl2,BCIN14,,,,,PHI:123560,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20976,PHI:123560,UniProt,A0A384JZT2,GenBank,ATZ56090,,,B05.10,Bcdcl1,BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20977,PHI:123561,UniProt,A0A384K344,GenBank,ATZ57233,,,B05.10,Bcdcl2,BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20978,PHI:123560,UniProt,A0A384JZT2,GenBank,ATZ56090,,,B05.10,Bcdcl1,BCIN12,,,,,PHI:123561,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20979,PHI:123561,UniProt,A0A384K344,GenBank,ATZ57233,,,B05.10,Bcdcl2,BCIN14,,,,,PHI:123560,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,dicer-like protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36168919,PubMed,10.1111/mpp.13269,Mol Plant Pathol. 2022 Sep 28,qiudewen@caas.cn,"No significant reduction in lesion size between the wild type and mutants on tomato, A. thaliana, Nicotiana benthamiana or Phaseolus vulgaris, were seen.",S Qin 2022,2022,2 genes,Qin-2022-Molecular characterization reveals no,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20980,PHI:123562,UniProt,R0KJY9,GenBank,EOA88327,,,Et28A,Slm2,chromosome unknown,,,,,,93612,Exserohilum turcicum,,01-23,northern corn leaf blight,monocots,4577,Zea mays (related: maize),B73 line,,,leaf,cytoskeleton regulator,,,,reduced virulence,,,,yes,,defective,,defective,,no,,,,,,,gene deletion: full,,,NN,34628700,PubMed,10.1111/mpp.13140,Mol Plant Pathol. 2022 Jan;23(1):32-44,shmzfl@hebau.edu.cn,The number of flecks formed on the leaves inoculated with mutant spores (Stslm2Δ) were significantly lower than that formed by the WT strain. (protein ID 168684),Y Meng 2022,2022,2 genes,Meng-2021-Novel factors contributing to fungal,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20981,PHI:123563,UniProt,R0KGT7,GenBank,EOA88484,,,Et28A,StACE1,chromosome unknown,,,,,,93612,Exserohilum turcicum,,01-23,northern corn leaf blight,monocots,4577,Zea mays (related: maize),B73 line,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,no,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,34628700,PubMed,10.1111/mpp.13140,Mol Plant Pathol. 2022 Jan;23(1):32-44,shmzfl@hebau.edu.cn,"The virulence of the StACE1Δ mutants was significantly reduced, and the mutant produced fewer and much smaller lesions on maize leaf than the WT strain.",Y Meng 2022,2022,2 genes,Meng-2021-Novel factors contributing to fungal,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20982,PHI:123564,UniProt,P0A3M9,GenBank,AAK75326,,,TIGR4; ATCC BAA-334,ldh(Sp_1220),,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,L-lactate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32495474,PubMed,10.1111/mmi.14557,Mol Microbiol. 2020 Oct;114(4):536-552,jason.rosch@stjude.org,"Mice infected with ldhdeletion mutant initially staved off morbidity, but ultimately succumbed to infection similar to TIGR4 infection.",H Echlin 2020,2020,6 genes,Echlin-2020-Role of the pyruvate metabolic net,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20983,PHI:123565,UniProt,A0A0H2UNL5,GenBank,AAK74619,,,TIGR4; ATCC BAA-334,pfl2(Sp_0459),,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,formate acetyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32495474,PubMed,10.1111/mmi.14557,Mol Microbiol. 2020 Oct;114(4):536-552,jason.rosch@stjude.org,Mice infected with pfl2 deletion mutant had a significant increase in survival.,H Echlin 2020,2020,6 genes,Echlin-2020-Role of the pyruvate metabolic net,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20984,PHI:123566,UniProt,Q54970,GenBank,AAK74871,,,TIGR4; ATCC BAA-334,spxB(Sp_0730),,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,pyruvate oxidase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32495474,PubMed,10.1111/mmi.14557,Mol Microbiol. 2020 Oct;114(4):536-552,jason.rosch@stjude.org,Mice infected with spxB deletion mutant had a significant increase in survival.,H Echlin 2020,2020,6 genes,Echlin-2020-Role of the pyruvate metabolic net,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20985,PHI:123567,UniProt,A0A0T7ZRS0,GenBank,CIT34206,,,37,pdhC,,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,branched-chain alpha-keto acid dehydrogenase E2 subunit,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32495474,PubMed,10.1111/mmi.14557,Mol Microbiol. 2020 Oct;114(4):536-552,jason.rosch@stjude.org,Mice infected with pdhC deletion mutant had a significant increase in survival.,H Echlin 2020,2020,6 genes,Echlin-2020-Role of the pyruvate metabolic net,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20986,PHI:123568,UniProt,A0A0H2UP66,GenBank,AAK74856,,,TIGR4; ATCC BAA-334,lctO,,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,lactate oxidase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32495474,PubMed,10.1111/mmi.14557,Mol Microbiol. 2020 Oct;114(4):536-552,jason.rosch@stjude.org,Loss of lctO did not significantly alter mouse survival in comparison with the parental TIGR4 strain.,H Echlin 2020,2020,6 genes,Echlin-2020-Role of the pyruvate metabolic net,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20987,PHI:123569,UniProt,A0A0H2UQ52,GenBank,AAK75212,,,TIGR4; ATCC BAA-334,pta(Sp_1100),,,,,,,1313,Streptococcus pneumoniae,170187,TIGR4,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,phosphate acetyltransferase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32495474,PubMed,10.1111/mmi.14557,Mol Microbiol. 2020 Oct;114(4):536-552,jason.rosch@stjude.org,Loss of pta did not significantly alter mouse survival in comparison with the parental TIGR4 strain.,H Echlin 2020,2020,6 genes,Echlin-2020-Role of the pyruvate metabolic net,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20988,PHI:123570,UniProt,S8EXT7,GenBank,EPT28286,,,ME49,AMPKβ (TGME49_268960),chromosome VIII,,,,,,5811,Toxoplasma gondii,508771,ME49,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,5'-AMP-activated protein kinase subunit beta-1 family protein,,,,loss of pathogenicity,,,,,,,,reduced; defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36205781,PubMed,10.1007/s00018-022-04556-z,Cell Mol Life Sci. 2022 Sep 28;79(10):532,jboothr@stanford.edu,"AMPKβ deletion mutant failed to cause any death of infected mice, suggesting a great attenuation of its virulence.",J Yang 2022,2022,1 gene,Yang-2022-The beta subunit of AMP-activated pr,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20989,PHI:123571,UniProt,A0A384JIP1,GenBank,ATZ50332,,,B05.10,Bccps1 (Bcin05g06910),BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Saxa,,,leaf,glycosyltransferase family 2 protein,,,,reduced virulence,,,,yes,,defective,,reduced; defective,wild type,no,,,,,,,gene deletion: full,,,NN,36135623,PubMed,10.3390/jof8090899,J Fungi (Basel). 2022 Aug 24;8(9):899.,christophe.bruel@univ-lyon1.fr,"Deletion of the Bccps1 gene does not affect the germination of the conidia but it perturbs hyphal expansion. It causes a severe reduction of mycelial growth in a solid medium. It strongly impairs plant penetration, plant colonization and the formation of sclerotia resulting in reduced virulence.",M Blandenet 2022,2022,1 gene,Blandenet-2022-Evidencing New Roles for the Gl,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20990,PHI:123572,UniProt,A0A1D9Q5R5,GenBank,XP_001592912,,,,SsFoxE3,,,,SsAtg8,UniProt: A7E8H4; GenBank: EDN96676,,5180,Sclerotinia sclerotiorum,,UF-1,stem rot,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,forkhead-box family transcription factor,,,,reduced virulence,,yes,,,,,,wild type,,no,calcofluor white; SDS; Congo red; H2O2,calcofluor white (CFW): CHEBI:50011; SDS: CHEBI:8984; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,34699137,PubMed,10.1111/mpp.13154,Mol Plant Pathol. 2022 Feb;23(2):204-217,panhongyu@jlu.edu.cn,Deletion of SsFoxE3 leads to reduced formation of compound appressoria and developmental delays and reduced virulence in host. SsFoxE3 interacted with the promoter of SsAtg8.,W Jiao 2022,2022,2 genes,Jiao-2021-Transcription factor SsFoxE3 activat,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20991,PHI:123573,UniProt,A7E8H4,GenBank,EDN96676,,,1980,SsAtg8,,,,SsFoxE3,,,5180,Sclerotinia sclerotiorum,,UF-1,stem rot,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,autophagy-related protein 8,,,,reduced virulence,,yes,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,34699137,PubMed,10.1111/mpp.13154,Mol Plant Pathol. 2022 Feb;23(2):204-217,panhongyu@jlu.edu.cn,"SsAtg8 deficiency reduced the formation of sclerotia. After inoculation of leaves, the pathogenicity of SsAtg8mutant was significantly decreased, and was recovered by the complemented strain SsAtg8-C.",W Jiao 2022,2022,2 genes,Jiao-2021-Transcription factor SsFoxE3 activat,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20992,PHI:123574,UniProt,L0PR31,GenBank,CCK33761,,,FR3054,BteA,,insertion of alanine residue at position 503,,,,,518,Bordetella bronchiseptica,,,infectious bronchitis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation; gene deletion: full,,,NN,33789161,PubMed,10.1016/j.jbc.2021.100607,J Biol Chem. 2021 Jan-Jun;296:100607,kamanova@biomed.cas.cz,Charge-reversal substitutions within the L1 region disrupted PM localization of the BteA effector without hampering its cytotoxic activity during B. bronchisepticainfection of HeLa cells.,I Malcova 2021,2021,1 gene,Malcova-2021-Lipid binding by the N-terminal m,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20993,PHI:123575,UniProt,Q8XWP6,GenBank,CAD16134,,,GMI1000,cysB (RSc2427),,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,,transcription regulator,,,PrhG-HrpB pathway,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35122373,PubMed,10.1111/mpp.13189,Mol Plant Pathol. 2022 May;23(5):679-692,bioyongzhang@swu.edu.cn,The cysB mutants failed to wilt tomato plants but remained weakly virulent on tobacco plants.,M Chen 2022,2022,2 genes,Chen-2022-A CysB regulator positively regulate,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20994,PHI:123575,UniProt,Q8XWP6,GenBank,CAD16134,,,GMI1000,cysB (RSc2427),,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,,transcription regulator,,,PrhG-HrpB pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35122373,PubMed,10.1111/mpp.13189,Mol Plant Pathol. 2022 May;23(5):679-692,bioyongzhang@swu.edu.cn,The cysB mutants failed to wilt tomato plants but remained weakly virulent on tobacco plants.,M Chen 2022,2022,2 genes,Chen-2022-A CysB regulator positively regulate,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20995,PHI:123576,UniProt,Q8XZP7,GenBank,CAD15050,,,GMI1000,Cbl (RSc1348),,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ailsa Craig,,,,transcription regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35122373,PubMed,10.1111/mpp.13189,Mol Plant Pathol. 2022 May;23(5):679-692,bioyongzhang@swu.edu.cn,The cbl mutants exhibited similar virulence to that of wild-type pathogen on the ohst plants.,M Chen 2022,2022,2 genes,Chen-2022-A CysB regulator positively regulate,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20996,PHI:123576,UniProt,Q8XZP7,GenBank,CAD15050,,,GMI1000,Cbl (RSc1348),,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Bright Yellow,,,,transcription regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35122373,PubMed,10.1111/mpp.13189,Mol Plant Pathol. 2022 May;23(5):679-692,bioyongzhang@swu.edu.cn,The cbl mutants exhibited similar virulence to that of wild-type pathogen on the ohst plants.,M Chen 2022,2022,2 genes,Chen-2022-A CysB regulator positively regulate,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20997,PHI:123577,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,ROP18,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,peritoneal fluid,serine/threonine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35084749,PubMed,10.1096/fj.202101347R,FASEB J. 2022 Feb;36(2):e22171.,floriapeng@hotmail.com,"The copies of B1 gene in RH-Δrop18 infected mice were significantly decreased compared with that in RH- WT infected mice, which indicated that the replication of RH-Δrop18 tachyzoites was significantly inhibited in mice.",M Chen 2022,2022,1 gene,Chen-2022-Toxoplasma gondii ROP18(I) inhibits,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20998,PHI:123577,UniProt,Q2PAY2,GenBank,AFO54811,,,OH3,ROP18,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),L929 cell line,,,fibroblast,serine/threonine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35084749,PubMed,10.1096/fj.202101347R,FASEB J. 2022 Feb;36(2):e22171.,floriapeng@hotmail.com,"The recruitment of Ub, p62 and LC3 adaptor proteins to the PVM were enhanced in the cells infected by RH-Δrop18 I compared with that in the cells infected by RH-WT demonstrating that TgROP18I was a virulence factor in mice.",M Chen 2022,2022,1 gene,Chen-2022-Toxoplasma gondii ROP18(I) inhibits,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 20999,PHI:123578,UniProt,X0JFE5,GenBank,EXL99917,,,54006,FoCupin1 (exl99917.1),,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4,vascular wilt,monocots,4641,Musa acuminata (related: dwarf banana),cv. Brazilian,,,root; leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36110302,PubMed,10.3389/fmicb.2022.1001540,Front Microbiol. 2022 Aug 30;13:1001540,huaping@scau.edu.cn,"The deletion of FoCupin1 gene did not affect Foc TR4 growth and conidiation. However, FoCupin1 deletion significantly reduced Foc TR4 virulence on banana plants.",T Yan 2022,2022,1 gene,"Yan-2022-FoCupin1, a Cupin_1 domain-containing",BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21000,PHI:123578,UniProt,X0JFE5,GenBank,EXL99917,,,54006,FoCupin1 (exl99917.1),,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense race 4,vascular wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,,,,,,,functional test in host: transient expression,,,NN,36110302,PubMed,10.3389/fmicb.2022.1001540,Front Microbiol. 2022 Aug 30;13:1001540,huaping@scau.edu.cn,The transient expression of FoCupin1 could suppress the plant defense responses in tobacco.,T Yan 2022,2022,1 gene,"Yan-2022-FoCupin1, a Cupin_1 domain-containing",BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21001,PHI:123579,UniProt,A0A2H3MBQ9,GenBank,EFG2884257,,,287551,Hcp2,,,,,,,562,Escherichia coli,,DE205B,avian colibacillosis,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,human brain microvascular endothelial cell,type VI secretion system protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36143390,PubMed,10.3390/life12091353,Life (Basel). 2022 Aug 31;12(9):1353,dyyrjl@njau.edu.cn,The invasion ability of the hcp2 deletion mutant strain to HBMECs was significantly decreased compared to the WT.,X Wang 2022,2022,2 genes,Wang-2022-Hcp Proteins of the Type VI Secretio,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21002,PHI:123580,UniProt,A0A1X9THD9,GenBank,ARR33228,,,5CRE51,Hcp1,,,,,,,562,Escherichia coli,,DE205B,avian colibacillosis,primates,9606,Homo sapiens (related: human),HBMEC-IM,,,human brain microvascular endothelial cell,type VI secretion system protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36143390,PubMed,10.3390/life12091353,Life (Basel). 2022 Aug 31;12(9):1353,dyyrjl@njau.edu.cn,The invasion ability of the hcp2 deletion mutant strain to HBMECs was not different compared to the WT.,X Wang 2022,2022,2 genes,Wang-2022-Hcp Proteins of the Type VI Secretio,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21003,PHI:123579,UniProt,A0A2H3MBQ9,GenBank,EFG2884257,,,287551,Hcp2,,,,,,,562,Escherichia coli,,DE205B,avian colibacillosis,rodents,10117,Rattus rattus (related: black rat),Sprague-Dawley,,,brain; liver; spleen; blood,type VI secretion system protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36143390,PubMed,10.3390/life12091353,Life (Basel). 2022 Aug 31;12(9):1353,dyyrjl@njau.edu.cn,The deletion of the hcp2 gene reduced the amount of DE205B invading brain tissue.,X Wang 2022,2022,2 genes,Wang-2022-Hcp Proteins of the Type VI Secretio,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21004,PHI:123581,UniProt,O51558,GenBank,AAC66962,,,B31,Lon-2 (BB0613),,,,,,,139,Borreliella burgdorferi,,CE162,Lyme disease,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,skin; heart; joint,Lon protease 2,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; tert-butyl hydroperoxide (tBOOH),NaCl: CHEBI:26710; tert-butyl hydroperoxide (tBOOH): CHEBI:64090,,,,,gene deletion: full; gene complementation,,,NN,31955462,PubMed,10.1111/mmi.14460,Mol Microbiol. 2020 May;113(5):938-950,zouyang@usf.edu,The infectivity of the lon-2 deletion mutant was severely attenuated in a murine infection model.,C Mason 2020,2020,1 gene,Mason-2020-The Lon-2 protease of Borrelia burg,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21005,PHI:123582,,no data found,GenBank,WP_011409781,,,,xopG,,E76A; E85A,,xopQ; xopX,UniProt: R4TJS0; GenBank: AGM16438; UniProt: A0A2K9IIK9; GenBank: QBN38003,,347,Xanthomonas oryzae,129394,pv. oryzae strain BXO43,bacterial leaf blight,monocots,4530,Oryza sativa (related: Rice),cv. Taichung Native-1,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation; gene mutation: characterised,,,NN,35150038,PubMed,10.1111/mpp.13184,Mol Plant Pathol. 2022 May;23(5):634-648,sonti@ccmb.res.in,"The XopG E76A and XopG E85A mutants are defective in interaction with XopQ and XopX, and are also defective in suppression of XopQ-XopX-mediated immune responses. Both mutations individually affect the virulence-promoting ability of XopG.",S Deb 2022,2022,1 gene,Deb-2022-Suppression of XopQ-XopX-induced immu,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21006,PHI:123583,,no data found,,,,,,Rs_T3E_Hyp14,,,,,,,305,Ralstonia solanacearum,,FJ1003,bacterial wilt,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Honghuadajinyuan,,,leaf,type III effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene mutation,,,NN,36072670,PubMed,10.3389/fgene.2022.966092,Front Genet. 2022 Aug 22;13:966092,hszou@fafu.edu.cn,"The pathogenicity of R. solanacearum on tobacco was significantly reduced after knockout of RS-T3E-Hyp14, and the colonization of R. solanacearum on a host was also affected.",K Chen 2022,2022,1 gene,Chen-2022-Comprehensive genome sequence analys,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21007,PHI:123584,UniProt,A0A1D8PIP6,GenBank,AOW27991,,,SC5314,Ubp8,chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,ubiquitin carboxyl-terminal hydrolase,,,,reduced virulence,,,,yes,,,,reduced,,no,fluconazole,fluconazole: CHEBI:46081,,,,,gene deletion: full,,,NN,33010070,PubMed,10.1111/mmi.14619,Mol Microbiol. 2021 Feb;115(2):332-343,jychen@sibcb.ac.cn,Deletion of Ubp8 impaired hyphal formation and a deficiency of invasive growth of C. albicans. UBP8 deletion delayed the death of infected mice.,W Zhu 2021,2021,1 gene,Zhu-2020-Bre1 and Ubp8 regulate H2B mono-ubiqu,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21008,PHI:123585,UniProt,Q5AFK0,GenBank,AOW30430,,,SC5314,Mac1p,chromosome 7,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,Cu binding transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,32808698,PubMed,10.1111/mmi.14591,Mol Microbiol. 2020 Dec;114(6):1006-1018,vculott1@jhu.edu,"The mac1Δ/Δstrain displayed a stark virulence defect, demonstrated by survival of mice.",E M Culbertson 2020,2020,1 gene,Culbertson-2020-Expanded role of the Cu-sensin,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21009,PHI:123586,UniProt,Q5AIR7,GenBank,AOW26046,,,SC5314,Eng1,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,"endo-1,3(4)-beta-glucanase 1",,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,34995333,PubMed,10.1371/journal.ppat.1010192,PLoS Pathog. 2022 Jan 7;18(1):e1010192,h4liu@uci.edu,"Deletion of ENG1 modulates virulence in the mouse model of hematogenously disseminated candidiasis in a Dectin-1-dependent manner. In male mice, the eng1 mutant showed attenuated virulence.",M Yang 2022,2022,1 gene,Yang-2022-Control of ß-glucan exposure by the,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21010,PHI:123586,UniProt,Q5AIR7,GenBank,AOW26046,,,SC5314,Eng1,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,"endo-1,3(4)-beta-glucanase 1",,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,34995333,PubMed,10.1371/journal.ppat.1010192,PLoS Pathog. 2022 Jan 7;18(1):e1010192,h4liu@uci.edu,"Deletion of ENG1 modulates virulence in the mouse model of hematogenously disseminated candidiasis in a Dectin-1-dependent manner. In female mice, the eng1 mutant showed enhanced virulence.",M Yang 2022,2022,1 gene,Yang-2022-Control of ß-glucan exposure by the,BATCH_116B,2022-11-01,MC,,,,,,,,,,,,,
,,Record 21011,PHI:123587,UniProt,B0Y3C3,GenBank,EDP51364,,,A1163,Elp3 (AFUB_053700),,,,Elp1; Elp2; Elp4; Elp5,UniProt: B0Y5Q6; GenBank: EDP50091; UniProt: B0YCU1; GenBank: EDP47475; UniProt: B0Y0V8; Gen,,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,elongator complex protein 3,,,,reduced virulence,,,,yes,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36374932,PubMed,10.1371/journal.ppat.1010976,PLoS Pathog. 2022 Nov 14;18(11):e1010976,linglu@njnu.edu.cn,Loss of Elp3 results defective colony phenotypes with impaired hyphal growth and reduced conidiation. Deletion of Elp3 caused reduced virulence.,Y Zhang 2022,2022,2 genes,Zhang-2022-Aspergillus fumigatus Elongator com,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21012,PHI:123587,UniProt,B0Y3C3,GenBank,EDP51364,,,A1163,Elp3 (AFUB_053700),,,,Elp1; Elp2; Elp4; Elp5,UniProt: B0Y5Q6; GenBank: EDP50091; UniProt: B0YCU1; GenBank: EDP47475; UniProt: B0Y0V8; Gen,,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,lung,elongator complex protein 3,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36374932,PubMed,10.1371/journal.ppat.1010976,PLoS Pathog. 2022 Nov 14;18(11):e1010976,linglu@njnu.edu.cn,Loss of Elp3 results defective colony phenotypes with impaired hyphal growth and reduced conidiation. Deletion of Elp3 caused reduced virulence.,Y Zhang 2022,2022,2 genes,Zhang-2022-Aspergillus fumigatus Elongator com,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21013,PHI:123587,UniProt,B0Y3C3,GenBank,EDP51364,,,A1163,Elp3 (AFUB_053700),,,,Elp1; Elp2; Elp4; Elp5,UniProt: B0Y5Q6; GenBank: EDP50091; UniProt: B0YCU1; GenBank: EDP47475; UniProt: B0Y0V8; Gen,PHI:123588,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,elongator complex protein 3,,,,unaffected pathogenicity,,,,,,wild-type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36374932,PubMed,10.1371/journal.ppat.1010976,PLoS Pathog. 2022 Nov 14;18(11):e1010976,linglu@njnu.edu.cn,"Deletion of cpcA from the Δelp3 mutant completely rescued the impaired hyphal growth, conidiation and virulence.",Y Zhang 2022,2022,2 genes,Zhang-2022-Aspergillus fumigatus Elongator com,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21014,PHI:123587,UniProt,B0Y3C3,GenBank,EDP51364,,,A1163,Elp3 (AFUB_053700),,,,Elp1; Elp2; Elp4; Elp5,UniProt: B0Y5Q6; GenBank: EDP50091; UniProt: B0YCU1; GenBank: EDP47475; UniProt: B0Y0V8; Gen,PHI:123588,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,elongator complex protein 3,,,,unaffected pathogenicity,,,,,,wild-type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36374932,PubMed,10.1371/journal.ppat.1010976,PLoS Pathog. 2022 Nov 14;18(11):e1010976,linglu@njnu.edu.cn,"Deletion of cpcA from the Δelp3 mutant completely rescued the impaired hyphal growth, conidiation and virulence.",Y Zhang 2022,2022,2 genes,Zhang-2022-Aspergillus fumigatus Elongator com,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21015,PHI:123588,UniProt,Q71S08,GenBank,AAQ14858,,,A1163,cpcA,,,,,,PHI:123587,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,cross-pathway control protein A,,,,unaffected pathogenicity,,,,,,wild-type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36374932,PubMed,10.1371/journal.ppat.1010976,PLoS Pathog. 2022 Nov 14;18(11):e1010976,linglu@njnu.edu.cn,"Deletion of cpcA from the Δelp3 mutant completely rescued the impaired hyphal growth, conidiation and virulence.",Y Zhang 2022,2022,2 genes,Zhang-2022-Aspergillus fumigatus Elongator com,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21016,PHI:123588,UniProt,Q71S08,GenBank,AAQ14858,,,A1163,cpcA,,,,,,PHI:123587,746128,Aspergillus fumigatus,,A1160,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,cross-pathway control protein A,,,,unaffected pathogenicity,,,,,,wild-type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36374932,PubMed,10.1371/journal.ppat.1010976,PLoS Pathog. 2022 Nov 14;18(11):e1010976,linglu@njnu.edu.cn,"Deletion of cpcA from the Δelp3 mutant completely rescued the impaired hyphal growth, conidiation and virulence.",Y Zhang 2022,2022,2 genes,Zhang-2022-Aspergillus fumigatus Elongator com,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21017,PHI:123589,,no data found,,,,,,rli143,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; kidney,small RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36297193,PubMed,10.3390/pathogens11101137,Pathogens. 2022 Sep 30;11(10):1137,qj710625@shzu.edu.cn,"The bacterial loads and pathological damages were alleviated,suggesting that sRNA Rli43 was involved in the modulation of the virulence of L. monocytogenes.",L Wang 2022,2022,1 gene,Wang-2022-A Regulatory SRNA Rli43 Is Involved,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21018,PHI:123590,,no data found,GenBank,PTC35039,,,CLJ1,exlA,,,,,,,287,Pseudomonas aeruginosa,,IHMA879472,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; liver; spleen,exolysin A,,,caspase-1/caspase-11-dependent and -independent pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,32779854,PubMed,10.1111/cmi.13251,Cell Microbiol. 2020 Nov;22(11):e13251,phuber@cea.fr,"Mice (either WT or KO) infected with IHMAΔexlA strain all survived, indicating that ExlA is the major virulence factor deployed by IHMA in vivo.",S Bouillot 2020,2020,1 gene,Bouillot-2020-Inflammasome activation by Pseud,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21019,PHI:123591,UniProt,Q2FV99,GenBank,ABD31836,,,NCTC 8325,SrtA,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,sortase A,,,,loss of pathogenicity,,,,,,,,wild type,,no,ML346,CAS:100872-83-1,,,,,gene deletion: full,,,NN,35308030,PubMed,10.1039/d1md00316j,RSC Med Chem. 2021 Nov 1;13(2):138-149,yangcg@simm.ac.cn,Deletion of srtA attenuated the pathogenicity of S. aureus.,X-N Guan 2022,2022,1 gene,Guan-2022-Covalent sortase A inhibitor ML346 p,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21020,PHI:123592,UniProt,A0A7Z6XWP1,GenBank,AYL80818,,,Shaanxi_M228,ompR,,,,,,,317,Pseudomonas syringae,103796,pv. actinidiae strain G1,bacterial canker,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,transcriptional regulators,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,NN,36293158,PubMed,10.3390/ijms232012306,Int J Mol Sci. 2022 Oct 14;23(20):12306,zbzhao@gzu.edu.cn,The deletion or overexpression of OmpR-like in Psa had no significant effect on its pathogenicity.,F Zhao 2022,2022,1 gene,Zhao-2022-The OmpR-like Transcription Factor a,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21021,PHI:123592,UniProt,A0A7Z6XWP1,GenBank,AYL80818,,,Shaanxi_M228,ompR,,,,,,,317,Pseudomonas syringae,103796,pv. actinidiae strain G1,bacterial canker,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,transcriptional regulators,,,,reduced virulence,,,,,,,,,,,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36293158,PubMed,10.3390/ijms232012306,Int J Mol Sci. 2022 Oct 14;23(20):12306,zbzhao@gzu.edu.cn,the deletion or overexpression of OmpR-like in Psa had no significant effect on its pathogenicity against its host tobacco.,F Zhao 2022,2022,1 gene,Zhao-2022-The OmpR-like Transcription Factor a,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21022,PHI:123592,UniProt,A0A7Z6XWP1,GenBank,AYL80818,,,Shaanxi_M228,ompR,,,,,,,317,Pseudomonas syringae,103796,pv. actinidiae strain G1,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),cv. Hongyang; cv. Guichang,,,shoot; leaf,transcriptional regulators,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,gene deletion: full,,,NN,36293158,PubMed,10.3390/ijms232012306,Int J Mol Sci. 2022 Oct 14;23(20):12306,zbzhao@gzu.edu.cn,The deletion or overexpression of OmpR-like in Psa had no significant effect on its pathogenicity.,F Zhao 2022,2022,1 gene,Zhao-2022-The OmpR-like Transcription Factor a,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21023,PHI:123592,UniProt,A0A7Z6XWP1,GenBank,AYL80818,,,Shaanxi_M228,ompR,,,,,,,317,Pseudomonas syringae,103796,pv. actinidiae strain G1,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),cv. Hongyang; cv. Guichang,,,shoot; leaf,transcriptional regulators,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36293158,PubMed,10.3390/ijms232012306,Int J Mol Sci. 2022 Oct 14;23(20):12306,zbzhao@gzu.edu.cn,The deletion or overexpression of OmpR-like in Psa had no significant effect on its pathogenicity.,F Zhao 2022,2022,1 gene,Zhao-2022-The OmpR-like Transcription Factor a,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21024,PHI:123593,UniProt,A0A0D1E3H5,GenBank,KIS70669,,,521,Erc1 (UMAG_01829),chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf; tassel,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion: full; gene complementation,,,NN,36224193,PubMed,10.1038/s41467-022-33815-7,Nat Commun. 2022 Oct 12;13(1):6003,bilal.oekmen@zmbp.uni-tyebingen.de.,Deletion of erc1 in U. maydis resulted in a significant reduction in fungal virulence.,B Okmen 2022,2022,2 genes,Ökmen-2022-A conserved enzyme of smut fungi fa,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21025,PHI:123594,,no data found,,,,,,Erc1,,,,,,,120017,Ustilago hordei,,DS199,covered smut,monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,,,,,,,,gene deletion: full; gene complementation,,,NN,36224193,PubMed,10.1038/s41467-022-33815-7,Nat Commun. 2022 Oct 12;13(1):6003,bilal.oekmen@zmbp.uni-tyebingen.de.,Deletion of erc1 in U. maydis resulted in a significant reduction in fungal virulence.,B Okmen 2022,2022,2 genes,Ökmen-2022-A conserved enzyme of smut fungi fa,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21026,PHI:123595,,no data found,,,,,,Pseudogene BMEA_B0173,,,,,,,29459,Brucella melitensis,520465,63/9,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,pseudogene,,,,increased virulence (hypervirulence),,,,,,,,wild type,,,,,,,,,gene deletion: full; gene complementation,,,NN,36329326,PubMed,10.1007/s00284-022-03078-y,Curr Microbiol. 2022 Nov 3;79(12):378,dingjiabo@126.com,BMEA_B0173 deletion exhibited increased virulence.,G Zhang 2022,2022,1 gene,Zhang-2022-The Pseudogene BMEA_B0173 Deficienc,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21027,PHI:123596,UniProt,A0A0B2XG51,GenBank,KHO11655,,,ARSEF 23,BrlA,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,,,,,loss of pathogenicity,,,yes,,,reduced,,wild type,,,H2O2; menadione; Congo red; calcofluor white ;,H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,36294676,PubMed,10.3390/jof8101110,J Fungi (Basel). 2022 Oct 21;8(10):1110,mgfeng@zju.edu.cn,"Aerial conidiation, submerged blastospore production mimicking yeast-like budding proliferation in insect hemocoel, and insect pathogenicity via cuticular penetration were all abolished as a consequence of brlA or abaA disruption.",J-G Zhang 2022,2022,2 genes,Zhang-2022-Roles of BrlA and AbaA in Mediating,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21028,PHI:123597,UniProt,E9EMI7,GenBank,EFZ03620,,,ARSEF 23,AbaA,,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,,,,,loss of pathogenicity,,,yes,,,reduced,,wild type,,,H2O2; menadione; Congo red; calcofluor white ;,H2O2: CHEBI:16240; menadione: CHEBI:28869; Congo red: CHEBI:34653; calcofluor white: CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,36294676,PubMed,10.3390/jof8101110,J Fungi (Basel). 2022 Oct 21;8(10):1110,mgfeng@zju.edu.cn,"Aerial conidiation, submerged blastospore production mimicking yeast-like budding proliferation in insect hemocoel, and insect pathogenicity via cuticular penetration were all abolished as a consequence of brlA or abaA disruption.",J-G Zhang 2022,2022,2 genes,Zhang-2022-Roles of BrlA and AbaA in Mediating,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21029,PHI:123598,UniProt,Q6T6T6,GenBank,AAR84051,,,DBS100,NleA,,Serine- and threonine-rich region 169-183 is deleted,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6; C3H/HeJ,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: partial; gene complementation,,,NN,36196760,PubMed,10.1111/mmi.14989,Mol Microbiol. 2022 Oct 5,samantha.gruenheid@mcgill.ca,Deletion of the modified region of NleA did not visibly alter virulence in the mouse infection model.,L Burns 2022,2022,1 gene,Burns-2022-The bacterial virulence factor NleA,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21030,PHI:123599,UniProt,E3QWE6,GenBank,EFQ35184,,,M1.001,Rho4 (GLRG_10328),,,,,,,31870,Colletotrichum graminicola,,M2,anthracnose (maize); leaf blight,monocots,4577,Zea mays (related: maize),cv. Badischer Landmais,,,leaf,Rho-type GTPase,,,,loss of pathogenicity,,,,yes,,reduced; defective,,reduced,defective,no,calcofluor white; KCl; sorbitol; caspofungin; nystatin,calcofluor white: CHEBI:50011; KCl: CHEBI:32588; sorbitol: CHEBI:17924; caspofungin: CHEBI:474180; nystatin: CHEBI:7660,,,,,gene deletion: full,,,NN,36294561,PubMed,10.3390/jof8100997,J Fungi (Basel). 2022 Sep 22;8(10):997,holger.deising@landw.uni-halle.de,"Deletion of rho4 resulted in distorted vegetative hyphae with swellings, exhibited strongly reduced rates of hyphal growth and defects in asexual sporulation. Δrho4 strains are nonpathogenic on wounded and non-wounded leaves of maize",G Oliveira 2022,2022,1 gene,Oliveira-Garcia-2022-The Small Ras Superfamily,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21031,PHI:123600,UniProt,Q84XU0,GenBank,AAO24646,,,P6497,Avh110,,conserved lysine (K) and arginine (R) residues were mutatuted to alanine (A) residues.,,,,,67593,Phytophthora sojae,1094619,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Hefeng 47,,,stem; leaf,effector protein,,,salicylic acid and pattern-triggered immunity signalling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation; gene mutation: characterised,,,NN,36222564,PubMed,10.1093/plcell/koac300,Plant Cell. 2022 Oct 12;koac300,wangyc@njau.edu.cn,PsAvh110 is a conserved effector utilized in the genus to manipulate plant immunity. The PsAvh110 mutants exhibited reduced virulence on etiolated soybean hypocotyls.,X Qiu 2022,2022,2 genes,Qiu-2022-The Phytophthora sojae nuclear effect,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21032,PHI:123601,,no data found,,,,,,Avh110,,conserved lysine (K) and arginine (R) residues were mutatuted to alanine (A) residues.,,,,,4784,Phytophthora capsici,,LT263,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,salicylic acid and pattern-triggered immunity signalling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene mutation: characterised,,,NN,36222564,PubMed,10.1093/plcell/koac300,Plant Cell. 2022 Oct 12;koac300,wangyc@njau.edu.cn,PsAvh110 is a conserved effector utilized in the genus to manipulate plant immunity.,X Qiu 2022,2022,2 genes,Qiu-2022-The Phytophthora sojae nuclear effect,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21033,PHI:123602,UniProt,A1XDS9,GenBank,ABC69140,,,,MIF,,,,,,,5811,Toxoplasma gondii,508771,ME49,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; brain,macrophage migration inhibitory factor,,,ERK/MAPK pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36281765,PubMed,10.1093/infdis/jiac422,J Infect Dis. 2022 Oct 25;jiac422,dujane@163.com,TgMIF gene deletion significantly alleviated liver injury and prolonged mice survival.,N Zhou 2022,2022,1 gene,Zhou-2022-TgMIF promotes hepatocyte pyroptosis,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21034,PHI:123603,UniProt,A0A1D9QDV7,GenBank,APA13135,,,1980,Sscle_10g079050,chromosome 10,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,necrotic lesions,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,amidase,,,glyoxylate pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36232508,PubMed,10.3390/ijms231911207,Int J Mol Sci. 2022 Sep 23;23(19):11207,xinli@msl.ubc.ca,"Deletion of gene Sscle_10g079050, resulted in reduced virulence on lettuce leaf, likely through affecting oxalic acid homeostasis.",W Li 2022,2022,2 genes,Li-2022-An Amidase Contributes to Full Virulen,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21035,PHI:123603,UniProt,A0A1D9QDV7,GenBank,APA13135,,,1980,Sscle_10g079050(L82S),chromosome 10,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,necrotic lesions,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,amidase,,,glyoxylate pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36232508,PubMed,10.3390/ijms231911207,Int J Mol Sci. 2022 Sep 23;23(19):11207,xinli@msl.ubc.ca,"Deletion of gene Sscle_10g079050, resulted in reduced virulence on lettuce leaf, likely through affecting oxalic acid homeostasis.",W Li 2022,2022,2 genes,Li-2022-An Amidase Contributes to Full Virulen,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21036,PHI:123604,UniProt,A0A1D9Q6U9,GenBank,APA10674,,,1980,Sscle_06g054440 (L1407S),chromosome 6,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,necrotic lesions,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,leaf,amidase,,,glyoxylate pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36232508,PubMed,10.3390/ijms231911207,Int J Mol Sci. 2022 Sep 23;23(19):11207,xinli@msl.ubc.ca,Transformation of the Sscle_06g054440 gene had no effect on virulence on lettuce leaf.,W.Li 2022,2022,2 genes,Li-2022-An Amidase Contributes to Full Virulen,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21037,PHI:123605,,no data found,,,,,,STnc1480,,,,lpfA,UniProt: A0A0H3NHA1; GenBank: CBW19699,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; intestine,sRNA,,,,reduced virulence,,,,,,,,wild type,,no,NaCl; H2O2,NaCl: CHEBI:26710; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36400974,PubMed,10.1007/s00203-022-03331-9,Arch Microbiol. 2022 Nov 19;204(12):716,xiaoshouyii@163.com,"Compared with parent and complement strains, the deficiency of the STnc1480 gene signifcantly reduced the bacterial loads in liver and spleen and the pathological damage was alleviated.",J Li 2022,2022,1 gene,Li-2022-The small RNA STnc1480 contributes to,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21038,PHI:123606,UniProt,P0A3S7,GenBank,AAK48919,,,16M,rPal (BMEI0340),chromosome 1,,,,,,29459,Brucella melitensis,224914,16M,brucellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,lipoprotein,,,,reduced virulence,,,,,,,,,,no,H2O2; polymyxin B,H2O2: CHEBI:16240; polymyxin B: CHEBI:8309,,,,,gene deletion: full; gene complementation,,,NN,36418790,PubMed,10.1007/s00284-022-03107-w,Curr Microbiol. 2022 Nov 22;80(1):2,532966952@163.com,Deletion of pal gene of Brucella resulted in a slight decline in virulence in mice.,Y Chen 2022,2022,1 gene,Chen-2022-Pal Affects the Proliferation in Mac,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21039,PHI:123607,UniProt,A0A0E0SDM9,GenBank,XP_011327965,,,PH-1; NRRL 31084,FgQdr2 (FGSG_09737),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet; coleoptile,DHA transporter,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,calcofluor white; sucrose; KCl; NaCl; CuSO4; EGTA; EDTA,calcofluor white: CHEBI:50011; sucrose: CHEBI:17992; KCl: CHEBI:32588; NaCl: CHEBI:26710; CuSO4: CHEBI:23414; EGTA: CHEBI:30740; EDTA: CHEBI:64758,,,,,gene deletion: full; gene complementation,,,NN,36294574,PubMed,10.3390/jof8101009,J Fungi (Basel). 2022 Sep 26;8(10):1009,yanleiyan@zju.edu.cn,"Deletion of FgQdr2 infected coleoptiles displayed shorter brown necrotic lesions than those of PH-1 ,indicating reduced virulence on wheat coleoptiles.",T Ma 2022,2022,1 gene,Ma-2022-The Drug H(+) Antiporter FgQdr2 Is Ess,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21040,PHI:123607,UniProt,A0A0E0SDM9,GenBank,XP_011327965,,,PH-1; NRRL 31084,FgQdr2 (FGSG_09737),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,DHA transporter,,,,reduced virulence,,,,,,reduced,reduced,reduced,,no,calcofluor white; sucrose; KCl; NaCl; CuSO4; EGTA; EDTA,calcofluor white: CHEBI:50011; sucrose: CHEBI:17992; KCl: CHEBI:32588; NaCl: CHEBI:26710; CuSO4: CHEBI:23414; EGTA: CHEBI:30740; EDTA: CHEBI:64760,,,,,gene deletion: full; gene complementation,,,NN,36294574,PubMed,10.3390/jof8101009,J Fungi (Basel). 2022 Sep 26;8(10):1009.,yanleiyan@zju.edu.cn,Deletion of FgQdr2 infects corn silk with reduced virulence compared to PH-1.,T Ma 2022,2022,1 gene,Ma-2022-The Drug H(+) Antiporter FgQdr2 Is Ess,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21041,PHI:123608,UniProt,Q2WCV5,GenBank,CAI77372,,,W22703,tcaA,,,,,,,630,Yersinia enterocolitica,913028,W22703,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative insecticidal toxin complex protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36399504,PubMed,10.1371/journal.ppat.1010991,PLoS Pathog. 2022 Nov 18;18(11):e1010991,thilom.fuchs@fli.de,"Larvae infected with Y. enterocolitica strain W22703 exhibited a significantly reduced survival rate compared to tcaA deletion mutant,which is atoxic for the insect.",P-A Sanger 2022,2022,4 genes,Sänger-2022-Dissecting the invasion of Galleri,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21042,PHI:123609,UniProt,Q2WCU7,GenBank,CAI77380,,,W22703,tccC,,,,,,,630,Yersinia enterocolitica,913028,W22703,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,putative insecticidal toxin complex protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36399504,PubMed,10.1371/journal.ppat.1010991,PLoS Pathog. 2022 Nov 18;18(11):e1010991,thilom.fuchs@fli.de,"Larvae infected with Y. enterocolitica strain W22703 exhibited a significantly reduced survival rate compared to tccC deletion mutant,which is atoxic for the insect.",P-A Sanger 2022,2022,4 genes,Sänger-2022-Dissecting the invasion of Galleri,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21043,PHI:123610,UniProt,Q2WCV0,GenBank,CAI77377,,,W22703,holY,,,,,,PHI:123611,630,Yersinia enterocolitica,913028,W22703,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,holin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36399504,PubMed,10.1371/journal.ppat.1010991,PLoS Pathog. 2022 Nov 18;18(11):e1010991,thilom.fuchs@fli.de,Larvae infected with Y. enterocolitica strain W22703 exhibited a significantly reduced survival rate compared to holin/endolysin deletion mutant.,P-A Sanger 2022,2022,4 genes,Sänger-2022-Dissecting the invasion of Galleri,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21044,PHI:123611,UniProt,Q2WCU9,GenBank,CAI77378,,,W22703,elyY,,,,,,PHI:123610,630,Yersinia enterocolitica,913028,W22703,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,endolysin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36399504,PubMed,10.1371/journal.ppat.1010991,PLoS Pathog. 2022 Nov 18;18(11):e1010991,thilom.fuchs@fli.de,Larvae infected with Y. enterocolitica strain W22703 exhibited a significantly reduced survival rate compared to holin/endolysin deletion mutant.,P-A Sanger 2022,2022,4 genes,Sänger-2022-Dissecting the invasion of Galleri,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21045,PHI:123612,UniProt,K3V9P2,GenBank,EKJ70149,,,CS3096,PEX11a (FPSE-09675),,,,,,,101028,Fusarium pseudograminearum,,,Fusarium crown rot; Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,coleoptile; spike,peroxisomal biogenesis factor 11,,,DON biosynthesis,reduced virulence,,,,,,reduced,,reduced; defective,reduced,no,SDS; Congo red; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36293041,PubMed,10.3390/ijms232012184,Int J Mol Sci. 2022 Oct 12;23(20):12184,zli@sdau.edu.cn,"PEX11a is involved in the regulation of vegetative growth, asexual reproduction and resulted in reduced pathogenicity of F. pseudograminearum.",M Wangh 2022,2022,3 genes,Wang-2022-Peroxisome Proliferator FpPEX11 Is I,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21046,PHI:123613,UniProt,K3V8W0,GenBank,EKJ70117,,,CS3096,PEX11b (FPSE-09643),,,,,,,101028,Fusarium pseudograminearum,,,Fusarium crown rot; Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,coleoptile; spike,peroxisomal biogenesis factor 11,,,DON biosynthesis,reduced virulence,,,,,,reduced,,reduced,wild type,no,SDS; Congo red; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36293041,PubMed,10.3390/ijms232012184,Int J Mol Sci. 2022 Oct 12;23(20):12184,zli@sdau.edu.cn,"PEX11b is involved in the regulation of vegetative growth, asexual reproduction and resulted in reduced pathogenicity of F. pseudograminearum.",M Wangh 2022,2022,3 genes,Wang-2022-Peroxisome Proliferator FpPEX11 Is I,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21047,PHI:123614,UniProt,K3W145,GenBank,EKJ75260,,,CS3096,PEX11c (FPSE_04578),,,,,,,101028,Fusarium pseudograminearum,,,Fusarium crown rot; Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,coleoptile; spike,peroxisomal biogenesis factor 11,,,DON biosynthesis,reduced virulence,,,,,,wild type,,wild type,wild type,no,SDS; Congo red; H2O2,sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36293041,PubMed,10.3390/ijms232012184,Int J Mol Sci. 2022 Oct 12;23(20):12184,zli@sdau.edu.cn,Deletion of FpPEX11c did not significantly affect the metabolic processes but resulted in reduced pathogenicity of F. pseudograminearum.,M Wangh 2022,2022,3 genes,Wang-2022-Peroxisome Proliferator FpPEX11 Is I,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21048,PHI:123615,UniProt,I1RYX6,GenBank,CEF83100,,,PH-1,LEU1 (FGS_09589),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,spikelet,3-isopropylmalate dehydratase,,,leucine biosynthesis,loss of pathogenicity,,,,,,reduced,reduced,reduced,reduced; defective,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,36294655,PubMed,10.3390/jof8101090,J Fungi (Basel). 2022 Oct 17;8(10):1090,zli@sdau.edu.cn,"Compared with the wild-type strain PH-1, ΔLEU1 showed slower colony growth and fewer aerial mycelia; complete loss of pathogenicity and reduced ability to produce deoxynivalenol (DON) and aurofusarin.",S Sun 2022,2022,1 gene,Sun-2022-FgLEU1 Is Involved in Leucine Biosynt,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21049,PHI:123615,UniProt,I1RYX6,GenBank,CEF83100,,,PH-1,LEU1 (FGS_09589),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,3-isopropylmalate dehydratase,,,leucine biosynthesis,loss of pathogenicity,,,,,,reduced,reduced,reduced,reduced; defective,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,36294655,PubMed,10.3390/jof8101090,J Fungi (Basel). 2022 Oct 17;8(10):1090,zli@sdau.edu.cn,"Compared with the wild-type strain PH-1, ΔLEU1 showed slower colony growth and fewer aerial mycelia; complete loss of pathogenicity and reduced ability to produce deoxynivalenol (DON) and aurofusarin.",S Sun 2022,2022,1 gene,Sun-2022-FgLEU1 Is Involved in Leucine Biosynt,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21050,PHI:123616,UniProt,G2WU90,GenBank,EGY17681,,,VdLs.17,VdERG2 (VDAG_01363),chromosome 1,,,,,,27337,Verticillium dahliae,,Vd080,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaf; stem,C-8 sterol isomerase,,,ergosterol biosynthesis,reduced virulence,,,yes,,,reduced,,reduced,reduced,no,Congo red; SDS; H2O2,Congo red: CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36416932,PubMed,10.1007/s00294-022-01257-9,Curr Genet. 2022 Nov 22,mkslch2013@163.com,"The conidial germination rate and conidial yield of ΔVdERG2 signifcantly decreased and abnormal conidia were produced; ΔVdERG2 could infect cotton, its pathogenicity was signifcantly impaired.",J Lv 2022,2022,1 gene,Lv-2022-VdERG2 was involved in ergosterol bios,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21051,PHI:123617,UniProt,A0A1Q6BES5,GenBank,OKV04987,,,700324,eutR,,,,,,,562,Escherichia coli,316401,H10407,neonatal meningitis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelial cell,ethanolamine utilization protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36370159,PubMed,10.1007/s00253-022-12261-x,Appl Microbiol Biotechnol. 2022 Dec;106(24):8195-8210,zhaoyanni@sust.edu.cn,"Expression levels of proinfammatory factors, such as TNF-α (3.2-fold), INF-γ (2.9-fold), and IL-1β (1.98-fold), in ETEC-infected Caco-2 cells were signifcantly upregulated following ethanolamine exposure; virulence changes were not found in ΔeutR ETEC.",X Lu 2022,2022,2 genes,Lu-2022-Effect of ethanolamine utilization on,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21052,PHI:123618,UniProt,A0A3Q0N0F3,GenBank,AUJ96932,,,531,eutB,,,,,,,562,Escherichia coli,316401,H10407,neonatal meningitis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,intestinal epithelial cell,ethanolamine utilization protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36370159,PubMed,10.1007/s00253-022-12261-x,Appl Microbiol Biotechnol. 2022 Dec;106(24):8195-8210,zhaoyanni@sust.edu.cn,"Expression levels of proinfammatory factors, such as TNF-α (3.2-fold), INF-γ (2.9-fold), and IL-1β (1.98-fold), in ETEC-infected Caco-2 cells were signifcantly upregulated following ethanolamine exposure; virulence changes were not found in ΔeutB ETEC.",X Lu 2022,2022,2 genes,Lu-2022-Effect of ethanolamine utilization on,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21053,PHI:123619,UniProt,Q9K362,GenBank,AAK08060,,,13751,HpaP,,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,ATPase and phosphatase,,,,reduced virulence,,,,,,,,reduced,,no,ampicillin; kanamycin; rifampicin; spectinomycin; streptomycin; tetracycline,ampicillin: CHEBI:28971; kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; spectinomycin: CHEBI:9215; streptomycin: CHEBI:17076; tetracycline: CHEBI:27902,,,,,gene deletion: full; gene complementation,,,NN,36260328,PubMed,10.1111/mpp.13276,Mol Plant Pathol. 2023 Jan;24(1):44-58,lugt@gxu.edu.cn,"Deletion of hpaP in Xoo led to a reduction in virulence and alteration in the production of virulence factors, including extracellular polysaccharide and cell motility.",R-F Li 2022,2022,3 genes,Li-2022-HpaP divergently regulates the express,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21054,PHI:123620,UniProt,Q0VHD2,GenBank,ABH07402,,,RS105,HpaP,,,,,,,347,Xanthomonas oryzae,129394,pv. oryzicola strain GX01,bacterial leaf blight,monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,ATPase and phosphatase,,,,reduced virulence,,,,,,,,reduced,,no,ampicillin; kanamycin; rifampicin; spectinomycin; streptomycin; tetracycline,ampicillin: CHEBI:28971; kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; spectinomycin: CHEBI:9215; streptomycin: CHEBI:17076; tetracycline: CHEBI:27902,,,,,gene deletion: full; gene complementation,,,NN,36260328,PubMed,10.1111/mpp.13276,Mol Plant Pathol. 2023 Jan;24(1):44-58,lugt@gxu.edu.cn,"Deletion of hpaP in Xoc led to a reduction in virulence and alteration in the production of virulence factors, including extracellular polysaccharide and cell motility.",R-F Li 2022,2022,3 genes,Li-2022-HpaP divergently regulates the express,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21055,PHI:123621,UniProt,Q4UX47,GenBank,AAY48376,,,8004,HpaP,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,4072,Capsicum annuum (no common name found),cv. Early Calwonder 10R,,,leaf,regulatory protein with ATPase and phosphatase activity,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); phenol; NaCl; H2O2; CoCl2; CdCl2,sodium dodecyl sulfate (SDS): CHEBI:8984; phenol: CHEBI:15882; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CoCl2: CHEBI:35696; CdCl2: CHEBI:35456,,,,,gene deletion: full; gene complementation,,,NN,36260328,PubMed,10.1111/mpp.13276,Mol Plant Pathol. 2023 Jan;24(1):44-58,lugt@gxu.edu.cn,Deletion of hpaP demonstrated reduced virulence and HR (hypersensitive response) induction of Xcc.,R-F Li 2022,2022,3 genes,Li-2022-HpaP divergently regulates the express,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21056,PHI:123621,UniProt,Q4UX47,GenBank,AAY48376,,,8004,HpaP,,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),Raphanus sativus var. niger (related: Chinese radish),,leaf,regulatory protein with ATPase and phosphatase activity,,,,reduced virulence,,,,,,,,,,no,sodium dodecyl sulfate (SDS); phenol; NaCl; H2O2; CoCl2; CdCl2,sodium dodecyl sulfate (SDS): CHEBI:8984; phenol: CHEBI:15882; NaCl: CHEBI:26710; H2O2: CHEBI:16240; CoCl2: CHEBI:35696; CdCl2: CHEBI:35456,,,,,gene deletion: full; gene complementation,,,NN,36260328,PubMed,10.1111/mpp.13276,Mol Plant Pathol. 2023 Jan;24(1):44-58,lugt@gxu.edu.cn,Deletion of hpaP demonstrated reduced virulence and HR (hypersensitive response) induction of Xcc.,R-F Li 2022,2022,3 genes,Li-2022-HpaP divergently regulates the express,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21057,PHI:123622,,no data found,,,,,,VdAve1L2,,,,,,,27337,Verticillium dahliae,,DVD-S26,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,root,effector protein,,,,effector (plant avirulence determinant),,,,,,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36300791,PubMed,10.1111/nph.18576,New Phytol. 2022 Oct 27,bthomma@uni-koeln.de,Effector VdAve1L2 promotes V. dahliae virulence through suppression of Actinobacteria.,N C Snelders 2022,2022,1 gene,Snelders-2022-A highly polymorphic effector pr,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21058,PHI:123623,UniProt,J9VYD5,GenBank,AFR98421,,,H99,CRK1 (CNAG_06193),chromosome 12,,,GPA1,UniProt: Q6XPR9; GenBank: AAP45151,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J; BALB/c,,,lung; brain; spleen,CDK-related kinase,,,cAMP/PKA signal pathway,unaffected pathogenicity,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36302775,PubMed,10.1038/s41467-022-34151-6,Nat Commun. 2022 Oct 27;13(1):6397,xuech@njms.rutgers.edu,"Mice infected with H99 or the crk1Δ mutant showed similar survival rates, suggesting that crk1Δ has no significant virulence attenuation.",C Cao 2022,2022,1 gene,Cao-2022-Ubiquitin proteolysis of a CDK-relate,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21059,PHI:123623,UniProt,J9VYD5,GenBank,AFR98421,,,H99,CRK1 (CNAG_06193),chromosome 12,,,GPA1,UniProt: Q6XPR9; GenBank: AAP45151,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J; BALB/c,,,lung; brain; spleen,CDK-related kinase,,,cAMP/PKA signal pathway,reduced virulence,,,,,,reduced,,increased,,no,,,,,,,altered gene expression / gene regulation: overexpression; gene deletion: partial,,,NN,36302775,PubMed,10.1038/s41467-022-34151-6,Nat Commun. 2022 Oct 27;13(1):6397,xuech@njms.rutgers.edu,"Mice infected with CRK1 (OE) or PEST-domain deletion strain survived significantly longer, indicating attenuated virulence.",C Cao 2022,2022,1 gene,Cao-2022-Ubiquitin proteolysis of a CDK-relate,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21060,PHI:123624,UniProt,D2UA79,GenBank,CBA15853,,,GPE PC73,rpfC,,Gln1510223Pro,,,,,29447,Xanthomonas albilineans,,NM10,leaf scald,monocots,4547,Saccharum officinarum (related: sugarcane),GT46 clone,,,leaf,two component system,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene mutation: characterised,,,NN,36162999,PubMed,10.1186/s12864-022-08900-2,BMC Genomics. 2022 Sep 26;23(1):671,zmuqing@163.com,The single-base mutation of rpfC in avirulent NM10 altered their pathogenicity.,M Li 2022,2022,6 genes,Li-2022-Comparative genome analysis unravels p,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21061,PHI:123625,UniProt,D2UA78,GenBank,CBA15852,,,GPE PC73,rpfG,,Arg1508978Ser,,,,,29447,Xanthomonas albilineans,,FS63,leaf scald,monocots,4547,Saccharum officinarum (related: sugarcane),GT46 clone,,,leaf,two component system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene mutation: characterised,,,NN,36162999,PubMed,10.1186/s12864-022-08900-2,BMC Genomics. 2022 Sep 26;23(1):671,zmuqing@163.com,"The single-base mutation of rpfG in the virulent FS63 altered their pathogenicity, indicating that the rpf gene mutation signifcantly infuenced strain virulence.",M Li 2022,2022,6 genes,Li-2022-Comparative genome analysis unravels p,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21062,PHI:123626,UniProt,D2UCV3,GenBank,CBA15664,,,GPE PC73,pyrG,,Ala1302440Val,,,,,29447,Xanthomonas albilineans,,FS12,leaf scald,monocots,4547,Saccharum officinarum (related: sugarcane),GT46 clone,,,leaf,CTP synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene mutation: characterised,,,NN,36162999,PubMed,10.1186/s12864-022-08900-2,BMC Genomics. 2022 Sep 26;23(1):671,zmuqing@163.com,The single-base SNPs mutations in the gene pyrG of FS12 strain did not alter their virulence.,M Li 2022,2022,6 genes,Li-2022-Comparative genome analysis unravels p,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21063,PHI:123627,UniProt,D2UDM3,GenBank,CBA15680,,,GPE PC73,folP,,Val1316885Ala; Ile1316974Val; Leu1317164Ser,,,,,29447,Xanthomonas albilineans,,FS12,leaf scald,monocots,4547,Saccharum officinarum (related: sugarcane),GT46 clone,,,leaf,dihydropteroate synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene mutation: characterised,,,NN,36162999,PubMed,10.1186/s12864-022-08900-2,BMC Genomics. 2022 Sep 26;23(1):671,zmuqing@163.com,The single-base SNPs mutations in the gene folP of FS12 strain did not alter their virulence.,M Li 2022,2022,6 genes,Li-2022-Comparative genome analysis unravels p,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21064,PHI:123628,UniProt,D2UCE7,GenBank,CBA15204,,,GPE PC73,VirD4,,Cys30557754Tyr; Glu3055887Asp; Ser3055836Val,,,,,29447,Xanthomonas albilineans,,FS12,leaf scald,monocots,4547,Saccharum officinarum (related: sugarcane),GT46 clone,,,leaf,type IV secretory system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene mutation: characterised,,,NN,36162999,PubMed,10.1186/s12864-022-08900-2,BMC Genomics. 2022 Sep 26;23(1):671,zmuqing@163.com,The single-base SNPs mutations in the gene VirD4 of FS12 strain did not alter their virulence.,M Li 2022,2022,6 genes,Li-2022-Comparative genome analysis unravels p,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21065,PHI:123629,UniProt,D2UEJ5,GenBank,CBA16592,,,GPE PC73,rhs,,Arg2749153Cys,,,,,29447,Xanthomonas albilineans,,FS25,leaf scald,monocots,4547,Saccharum officinarum (related: sugarcane),GT46 clone,,,leaf,type IV secretion protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene mutation: characterised,,,NN,36162999,PubMed,10.1186/s12864-022-08900-2,BMC Genomics. 2022 Sep 26;23(1):671,zmuqing@163.com,The single-base SNPs mutations in the gene rhs of FS25 strain did not alter their virulence.,M Li 2022,2022,6 genes,Li-2022-Comparative genome analysis unravels p,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21066,PHI:123630,UniProt,A0A1C3YHJ5,GenBank,SCB64027,,,PH-1,FgDBR1,chromosome 1,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,debranching enzyme,,,,reduced virulence,,,,,,reduced; defective,reduced,reduced,,no,hydroxyurea; methyl methanesulfonate; H2O2; menadione; NaCl; KCl; sorbitol; FeSO4; hygromycin B; cycloheximide; SDS; Congo red; fludioxonil; iprodione; benomyl; tebuconazole,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; H2O2: CHEBI:16240; menadione: CHEBI:28869; NaCl: CHEBI:26710; KCl: CHEBI:32588; sorbitol: CHEBI:17924; FeSO4: CHEBI:75832; hygromycin B: CHEBI:16976; cycloheximide: CHEBI:27641; sodium dodecyl sulfate (SDS): CHEBI:8984; Congo red: CHEBI:34653; fludioxonil: CAS:131341-86-1; iprodione: CHEBI:28909; benomyl: CHEBI:3015; tebuconazole: CHEBI:81781,,,,,gene deletion: full; gene complementation,,,NN,36289323,PubMed,10.1038/s42003-022-04111-3,Commun Biol. 2022 Oct 26;5(1):1129,hogongi7@snu.ac.kr,"Deletion of FgDBR1 resulted in pleiotropic defects in hyphal growth, conidiation, sexual reproduction, and virulence.",Y Choi 2022,2022,1 gene,Choi-2022-Intron turnover is essential to the,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21067,PHI:123631,UniProt,Q48Q24,GenBank,AAZ33160,,,1448A; BAA-978,oxyR (PSPPH_0190),,pBBR1MCS-5::oxyR250,,,,,29438,Pseudomonas savastanoi,319,pv. phaseolicola strain NPS3121,halo blight,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,pod,oxidative stress regulatory protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,36363715,PubMed,10.3390/microorganisms10112123,Microorganisms. 2022 Oct 27;10(11):2123,lizzeta28@gmail.com,"Absence of formation of halos of growth inhibition in the oxyR-mutant strain assays at both evaluated temperatures (18 ◦C and 28 ◦C), compared with the wt strain.",J L Arvizu-Gómez 2022,2022,1 gene,Arvizu-Gómez-2022-OxyR Positively Influences P,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21068,PHI:123632,UniProt,A7E6B5,GenBank,EDN91437,,,1980,SsAOX (SS1G_00840),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3847,Glycine max (related: soybean),,,,stem; leaf,alcohol oxidase,,,,reduced virulence,,,,,reduced stem lesion,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36251755,PubMed,10.1111/mpp.13274,Mol Plant Pathol. 2023 Jan;24(1):28-43,kabbage@wisc.edu,Disease assays in soybean showed that ΔSsAOX mutant had a significant virulence defect as evidenced by markedly reduced stem lesions and mortality rates.,N M Westrick 2022,2022,1 gene,Westrick-2022-A broadly conserved fungal alcoh,BATCH_117A,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21069,PHI:123633,UniProt,A0A8E6Y917,GenBank,CDS71140,,,,citA,chromosome I,,,,,PHI:123634,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21070,PHI:123633,UniProt,A0A8E6Y917,GenBank,CDS71140,,,,citA,chromosome I,,,,,PHI:123634; PHI:123635; PHI:123636; PHI:123637; PHI:123638,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21071,PHI:123634,UniProt,A0A8E6Y534,GenBank,CDS71138,,,,citB,chromosome I,,,,,PHI:123633,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21072,PHI:123634,UniProt,A0A8E6Y534,GenBank,CDS71138,,,,citB,chromosome I,,,,,PHI:123633; PHI:123635; PHI:123636; PHI:123637; PHI:123638,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21073,PHI:123635,UniProt,A0A8E6Y534,GenBank,QVT75833,,,CFSAN022627,dpiA,,,,,,PHI:123636,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21074,PHI:123635,UniProt,A0A8E6Y534,GenBank,QVT75833,,,CFSAN022627,dpiA,,,,,,PHI:123633; PHI:123634; PHI:123636; PHI:123637; PHI:123638,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21075,PHI:123636,UniProt,A0A8E6Y6B3,GenBank,QVT75832,,,CFSAN022627,dpiB,,,,,,PHI:123635,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21076,PHI:123636,UniProt,A0A8E6Y6B3,GenBank,QVT75832,,,CFSAN022627,dpiB,,,,,,PHI:123633; PHI:123634; PHI:123635; PHI:123637; PHI:123638,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21077,PHI:123637,UniProt,no data found,GenBank,SUG07373,,,NCTC10705,DcuS,,,,,,PHI:123638,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21078,PHI:123637,UniProt,no data found,GenBank,SUG07373,,,NCTC10705,DcuS,,,,,,PHI:123633; PHI:123634; PHI:123635; PHI:123636; PHI:123638,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21079,PHI:123638,UniProt,A0A8E6Y3T8,GenBank,QVT74130,,,CFSAN022627,DcuR,,,,,,PHI:123637,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21080,PHI:123638,UniProt,A0A8E6Y3T8,GenBank,QVT74130,,,CFSAN022627,DcuR,,,,,,PHI:123633; PHI:123634; PHI:123635; PHI:123636; PHI:123637,28901,Salmonella enterica,1298917,subsp. enterica serovar Pullorum strain S06004,pullorum disease,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,egg; embryo; liver; spleen,two-component system,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36077599,PubMed,10.3390/ijms231710201,Int J Mol Sci. 2022 Sep 5;23(17):10201,myue@zju.edu.cn,"Mutants showed thicker biofilm formation, higher resistance to antimicrobial agents and increased virulence in chicken embryos.",X Kang 2022,2022,6 genes,Kang-2022-Characterization of Two-Component Sy,BATCH_116C,2022-12-01,MC,,,,,,,,,,,,,
,,Record 21081,PHI:123639,UniProt,P08190,GenBank,CAA29155,,,,fimG,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,fimbrial protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,"Animal infection assay using ΔfimG and WT strain, it was shown that the mutant strain displayed significantly reduced colonization in the brain (CI=0.158), spleen (CI=0.591), and lung (CI=0.338) compared with the WT strain",F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21082,PHI:123640,UniProt,P0A8U6,GenBank,AAA24163,,,,metJ,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,ΔmetJ strain had a very low competitive index indicating a significant colonization defect compared with the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21083,PHI:123641,UniProt,P30847,GenBank,BAA03140,,,K-12,baeS,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,histidine kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,ΔbaeS was significantly attenuated compared with the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21084,PHI:123642,UniProt,P23877,GenBank,CAA40708,,,K-12,fepG,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,"Mutant strain displayed significantly reduced colonization in the brain (CI=0.158), spleen (CI=0.591), and lung (CI=0.338) compared with the WT strain.",F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21085,PHI:123643,UniProt,P0ABN5,GenBank,CAA56259,,,K-12,dcuA,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,The mice infected with ΔdcuA showed comparable virulence to the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21086,PHI:123644,UniProt,P0AEL6,GenBank,AAA83853,,,K-12,fepB,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,"Colonize in the brain, spleen, and lung tissues of mice was significantly lower than that of the WT strain.",F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21087,PHI:123645,UniProt,P0ABM9,GenBank,AAA16386,,,,ccmH,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,The mice infected with ΔccmH showed comparable virulence to the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21088,PHI:123646,UniProt,P69054,GenBank,AAA23893,,,,sdhC,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,Mice infected with ΔsdhC showed significantly higher survival.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21089,PHI:123647,UniProt,P0AER8,GenBank,BAA00517,,,B,gltS,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,The mice infected with ΔgltS showed comparable virulence to the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21090,PHI:123648,UniProt,P37758,GenBank,CAA64448,,,K-12,narU,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,The mice infected with ΔnarU showed comparable virulence to the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21091,PHI:123649,UniProt,P31550,GenBank,AAA18833,,,C600,yabL,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,The mice infected with ΔyabL showed comparable virulence to the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21092,PHI:123650,UniProt,P03841,GenBank,AAB59059,,,,malM,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,The mice infected with ΔmalM showed comparable virulence to the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21093,PHI:123651,UniProt,P77268,GenBank,AAC74557,,,K-12,ddpD,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,Mice infected with ΔddpD showed significantly higher survival.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21094,PHI:123652,UniProt,P13035,GenBank,AAA24636,,,K-12,glpD,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,The mice infected with ΔglpD showed comparable virulence to the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21095,PHI:123653,UniProt,P27243,GenBank,AAA24524,,,K-12,rfa L,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,lipopolysaccharide heptosyltransferase 1,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,rfa strain showed a reduced ability to colonize in mice; The growth assay revealed that Δrfa showed slightly reduced growth in LB medium compared with the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21096,PHI:123654,UniProt,P27129,GenBank,AAA24087,,,K-12,rfaJ,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,lipopolysaccharide heptosyltransferase 1,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,rfa strain showed a reduced ability to colonize in mice; The growth assay revealed that Δrfa showed slightly reduced growth in LB medium compared with the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21097,PHI:123655,UniProt,P27128,GenBank,AAA24086,,,K-12,rfaI,,,,,,,562,Escherichia coli,1001989,PCN033,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,brain; spleen; lung,lipopolysaccharide heptosyltransferase 1,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36537189,PubMed,10.1080/21505594.2022.2158708,Virulence. 2022 Dec 20,rzhou@mail.hzau.edu.cn,rfa strain showed a reduced ability to colonize in mice; The growth assay revealed that Δrfa showed slightly reduced growth in LB medium compared with the WT strain.,F Yin 2022,2022,17 genes,Yin et al 2023 KVIR_14_2158708,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21098,PHI:123656,UniProt,A0A0D2Y4V0,GenBank,KNB11402,,,4287,PAT1 (FOXG_11304),chromosome 1,,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),,,,stem; root,palmitoyltransferase,,,,reduced virulence,,,yes,,,reduced,,reduced,reduced,no,SDS; Congo red; NaCl; H2O2; calcofluor white; CaCl2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,NN,36533963,PubMed,10.1128/spectrum.03861-22,Microbiol Spectr. 2022 Dec 19;e0386122,dyli@zju.edu.cn,"At 27 dpi, 56%of the ΔFonpat1- inoculated plants survived, while all of the WT-inoculated plants died.",X Xiong 2022,2022,10 genes,Xiong et al 2023 spectrum.03861-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21099,PHI:123657,UniProt,A0A0J9UX14,GenBank,KNB03914,,,4287,PAT2 (FOXG_06235),chromosome 2a,,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),,,,stem; root,palmitoyltransferase,,,,reduced virulence,,,yes,,,reduced,,reduced; defective,reduced,no,SDS; Congo red; NaCl; H2O2; calcofluor white; CaCl2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,NN,36533963,PubMed,10.1128/spectrum.03861-22,Microbiol Spectr. 2022 Dec 19;e0386122,dyli@zju.edu.cn,"At 27 dpi, 72%of the ΔFonpat2- inoculated plants survived, while all of the WT-inoculated plants died.",X Xiong 2022,2022,10 genes,Xiong et al 2023 spectrum.03861-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21100,PHI:123658,UniProt,A0A0D2XUG0,GenBank,KNB05288,,,4287,PAT3 (FOXG_07613),chromosome 4,,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),,,,stem; root,palmitoyltransferase,,,,unaffected pathogenicity,,,,,,reduced,,wild type,reduced,no,SDS; Congo red; NaCl; H2O2; calcofluor white; CaCl2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full,,,NN,36533963,PubMed,10.1128/spectrum.03861-22,Microbiol Spectr. 2022 Dec 19;e0386122,dyli@zju.edu.cn,Disease severities of the ΔFonpat3-inoculated plants were comparable to that of wild type (WT)-inoculated plants.,X Xiong 2022,2022,10 genes,Xiong et al 2023 spectrum.03861-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21101,PHI:123659,UniProt,A0A0J9UGG6,GenBank,KNA97947,,,4287,PAT4(FOXG_02420),chromosome 5,,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),,,,stem; root,palmitoyltransferase,,,,reduced virulence,,,yes,,,reduced,,wild type,reduced,no,SDS; Congo red; NaCl; H2O2; calcofluor white; CaCl2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,NN,36533963,PubMed,10.1128/spectrum.03861-22,Microbiol Spectr. 2022 Dec 19;e0386122,dyli@zju.edu.cn,"At 27 dpi, 69%of the ΔFonpat4- inoculated plants survived, while all of the WT-inoculated plants died.",X Xiong 2022,2022,10 genes,Xiong et al 2023 spectrum.03861-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21102,PHI:123660,UniProt,A0A0D2XHD7,GenBank,KNA99375,,,4287,PAT5 (FOXG_03335),chromosome 8,,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),,,,stem; root,palmitoyltransferase,,,,unaffected pathogenicity,,,,,,reduced,,wild type,reduced,no,SDS; Congo red; NaCl; H2O2; calcofluor white; CaCl2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full,,,NN,36533963,PubMed,10.1128/spectrum.03861-22,Microbiol Spectr. 2022 Dec 19;e0386122,dyli@zju.edu.cn,Disease severities of the ΔFonpat5-inoculated plants were comparable to that of wild type (WT)-inoculated plants.,X Xiong 2022,2022,10 genes,Xiong et al 2023 spectrum.03861-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21103,PHI:123661,UniProt,A0A0J9UKE8,GenBank,KNA99903,,,4287,PAT6 (FOXG_03646),chromosome 8,,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),,,,stem; root,palmitoyltransferase,,,,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,SDS; Congo red; NaCl; H2O2; calcofluor white; CaCl2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full,,,NN,36533963,PubMed,10.1128/spectrum.03861-22,Microbiol Spectr. 2022 Dec 19;e0386122,dyli@zju.edu.cn,Disease severities of the ΔFonpat6-inoculated plants were comparable to that of wild type (WT)-inoculated plants.,X Xiong 2022,2022,10 genes,Xiong et al 2023 spectrum.03861-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21104,PHI:123662,UniProt,A0A0J9UA97,GenBank,KNA95030,,,4287,nap-2α (FOXG_00780),chromosome 1,,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),,,,stem; root,palmitoylation of FonAP-2 complex subunits,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,SDS; Congo red; NaCl; H2O2; calcofluor white; CaCl2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,NN,36533963,PubMed,10.1128/spectrum.03861-22,Microbiol Spectr. 2022 Dec 19;e0386122,dyli@zju.edu.cn,"The ΔFonap-2α-inoculated plants showed fewer disease symptoms and reduced disease severity, leading to reductions of disease severity of 58.2% compared with that in WT-inoculated plants.",X Xiong 2022,2022,10 genes,Xiong et al 2023 spectrum.03861-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21105,PHI:123663,UniProt,A0A0J9V733,GenBank,KNB06990,,,4287,nap-2β (FOXG_08330),chromosome 2a,,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),,,,stem; root,palmitoylation of FonAP-2 complex subunits,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,SDS; Congo red; NaCl; H2O2; calcofluor white; CaCl2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,NN,36533963,PubMed,10.1128/spectrum.03861-22,Microbiol Spectr. 2022 Dec 19;e0386122,dyli@zju.edu.cn,"The ΔFonap-2β-inoculated plants showed fewer disease symptoms and reduced disease severity, leading to reductions of disease severity of 55.9% compared with that in WT-inoculated plants.",X Xiong 2022,2022,10 genes,Xiong et al 2023 spectrum.03861-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21106,PHI:123664,UniProt,A0A0J9UPD6,GenBank,KNB01145,,,4287,nap-2µ ( FOXG_04448),chromosome 4,,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),,,,stem; root,palmitoylation of FonAP-2 complex subunits,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,SDS; Congo red; NaCl; H2O2; calcofluor white; CaCl2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,NN,36533963,PubMed,10.1128/spectrum.03861-22,Microbiol Spectr. 2022 Dec 19;e0386122,dyli@zju.edu.cn,"The ΔFonap-2µ-inoculated plants showed fewer disease symptoms and reduced disease severity, leading to reductions of disease severity of 41.8% compared with that in WT-inoculated plants.",X Xiong 2022,2022,10 genes,Xiong et al 2023 spectrum.03861-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21107,PHI:123665,UniProt,A0A0D2XX76,GenBank,KNB07424,,,4287,nap-2σ (FOXG_08592),chromosome 2a,,,,,,5507,Fusarium oxysporum,120297,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),,,,stem; root,palmitoylation of FonAP-2 complex subunits,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,SDS; Congo red; NaCl; H2O2; calcofluor white; CaCl2,SDS: CHEBI:8984; congo red: CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; calcofluor white: CHEBI:50011; CaCl2: CHEBI:3312,,,,,gene deletion: full; gene complementation,,,NN,36533963,PubMed,10.1128/spectrum.03861-22,Microbiol Spectr. 2022 Dec 19;e0386122,dyli@zju.edu.cn,"The ΔFonap-2σ-inoculated plants showed fewer disease symptoms and reduced disease severity, leading to reductions of disease severity of 58.2% compared with that in WT-inoculated plants.",X Xiong 2022,2022,10 genes,Xiong et al 2023 spectrum.03861-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21108,PHI:123666,UniProt,Q59T95,GenBank,AOW25874,,,SC5314,cys4,chromosome 1,,,,,,5476,Candida albicans,,CAF2-1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cystathionine beta-synthase,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; menadione; N-acetylcysteine,H2O2: CHEBI:16240; menadione: CHEBI:28869; N-acetylcysteine: CHEBI:28939,,,,,gene deletion: full; gene complementation,,,NN,36525499,PubMed,10.1126/sciadv.add5366,Sci Adv. 2022 Dec 16;8(50):eadd5366,changwenqiang@sdu.edu.cn,"Deletion of CBS leads to deficiencies in resistance to oxidative stress, retarded cell growth, defective hyphal growth, and increased β-glucan exposure, which, together, reduce the pathogenicity of C. albicans.",W Chang 2022,2022,1 gene,Chang et al 2023 sciadv.add5366,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21109,PHI:123667,UniProt,A0A125YI56,GenBank,EPT25917,,,ME49,TGME49_313440,chromosome 11,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_313440 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21110,PHI:123668,UniProt,A0A125YJ91,GenBank,EPT24940,,,ME49,TGME49_247530,chromosome 12,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_247530 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21111,PHI:123669,UniProt,S8F8Y3,GenBank,EPT30043,,,ME49,TGME49_204320,chromosome 7a,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_204320 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21112,PHI:123670,UniProt,S8GBI7,GenBank,EPT25694,,,ME49,TGME49_315910,chromosome 11,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,Disruption of TGME49_315910 did not attenuate the virulence of the RH strain.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21113,PHI:123671,UniProt,S8GK08,GenBank,EPT32205,,,ME49,TGME49_297900,chromosome 2,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_297900 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21114,PHI:123672,UniProt,S8EYU6,GenBank,EPT27547,,,ME49,TGME49_267740,chromosome 9,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_267740 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21115,PHI:123673,UniProt,S8F0Y5,GenBank,EPT28287,,,ME49,TGME49_268970,chromosome 8,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_268970 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21116,PHI:123674,UniProt,S8G730,GenBank,EPT27530,,,ME49,TGME49_279350,chromosome 9,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_279350 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21117,PHI:123675,UniProt,S8F3Y2,GenBank,EPT29342,,,ME49,TGME49_258462,chromosome 7b,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_258462 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21118,PHI:123676,UniProt,S8GDN9,GenBank,EPT26544,,,ME49,TGME49_214410,chromosome 10,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_214410 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21119,PHI:123677,UniProt,A0A125YFC4,GenBank,EPT28088,,,ME49,TGME49_291630,chromosome 9,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_291630 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21120,PHI:123678,UniProt,S8ES16,GenBank,EPT25062,,,ME49,TGME49_248990,chromosome 7,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_248990 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21121,PHI:123679,UniProt,S8FAA0,GenBank,EPT30578,,,ME49,TGME49_244530,chromosome 6,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_244530 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21122,PHI:123680,UniProt,S8F116,GenBank,EPT29341,,,ME49,TGME49_258458,chromosome 7b,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_258458 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21123,PHI:123681,UniProt,S8EW26,GenBank,EPT27661,,,ME49,TGME49_266410,chromosome 9,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,Mice infected with tachyzoites of the TGME49_266410 mutant strain had slightly longer survival time compared with that of the wild-type RH strain infected group in acute infection.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21124,PHI:123670,UniProt,S8GBI7,GenBank,EPT25694,,,ME49,TGME49_315910,chromosome 11,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,Disruption of TGME49_315910 showed increased survival of mice.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21125,PHI:123676,UniProt,S8GDN9,GenBank,EPT26544,,,ME49,TGME49_214410,chromosome 10,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_214410 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21126,PHI:123678,UniProt,S8ES16,GenBank,EPT25062,,,ME49,TGME49_248990,chromosome 7,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_248990 had no statistically significant effect on the mouse survival time.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21127,PHI:123680,UniProt,S8F116,GenBank,EPT29341,,,ME49,TGME49_258458,chromosome 7b,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,The survival rate of infected mice with ΔTGME49_258458 had no statistically significant difference with wild-type strain infected group.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21128,PHI:123681,UniProt,S8EW26,GenBank,EPT27661,,,ME49,TGME49_266410,chromosome 9,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,effector protein,,,signaling pathway,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36515555,PubMed,10.1128/spectrum.03078-22,Microbiol Spectr. 2022 Dec 14;e0307822,xingquanzhu1@hotmail.com,Disruption of TGME49_266410 showed increased survival of mice.,X-N Zheng 2022,2022,15 genes,Zheng et al 2023 spectrum.03078-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21129,PHI:123682,UniProt,A0A0J9VQD6,GenBank,KNB13133,,,4287,Dbp40 (FOXG_12762),chromosome 9,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain JLCC31768,Fusarium wilt,bony fishes,7955,Danio rerio (related: zebrafish),AB,,,,hypothetical protein,,,AMPK/mTOR signaling pathway,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36519161,PubMed,10.3389/fmicb.2022.1050637,Front Microbiol. 2022 Nov 28;13:1050637,wli99@jlu.edu.cn,F. oxysporum growth and virulence decreased after FoDbp40 deletion.,B Zhao 2022,2022,1 gene,Zhao B et al 2023 mpmi-08-22-0165-r,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21130,PHI:123682,UniProt,A0A0J9VQD6,GenBank,KNB13133,,,4287,Dbp40 (FOXG_12762),chromosome 9,,,,,,5507,Fusarium oxysporum,59765,f. sp. lycopersici strain JLCC31768,Fusarium wilt,primates,9606,Homo sapiens (related: human),,,,corneal epithelial cell,hypothetical protein,,,AMPK/mTOR signaling pathway,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36519161,PubMed,10.3389/fmicb.2022.1050637,Front Microbiol. 2022 Nov 28;13:1050637,wli99@jlu.edu.cn,F. oxysporum growth and virulence decreased after FoDbp40 deletion.,B Zhao 2022,2022,1 gene,Zhao B et al 2023 mpmi-08-22-0165-r,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21131,PHI:123683,UniProt,O86331,GenBank,CCP43540,,,H37Rv,Rv0792c,,,,,,,1773,Mycobacterium tuberculosis,,,tuberculosis,rodents,10141,Cavia porcellus (related: Domestic Guinea pig),Hartley,,,lung,transcriptional regulatory protein,,,metabolic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36507689,PubMed,10.1128/spectrum.01973-22,Microbiol Spectr. 2022 Dec 12;e0197322,ramandeep@thsti.res.in,The number of lesions was significantly reduced in lung tissues from mutant strain-infected guinea pigs at both 28 and 56 days postinfection.,N K Chauhan 2022,2022,1 gene,Chauhan et al 2023 spectrum.01973-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21132,PHI:123684,,no data found,,,,,,zrgA,,,,,,,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36482737,PubMed,10.1080/21505594.2022.2156196,Virulence. 2022 Dec 8,zhouxh@sustech.edu.cn,There was no significant difference in the survival rates of mice between the WT- and Δ1470.,C Zheng 2022,2022,3 genes,Zheng C et al 2023 ZrgA contributes to zinc ac,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21133,PHI:123684,,no data found,,,,,,zrgA,,,,,,PHI:123685; PHI:123686,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36482737,PubMed,10.1080/21505594.2022.2156196,Virulence. 2022 Dec 8,zhouxh@sustech.edu.cn,There was no significant difference in the survival rates of mice between the triple mutant Δ1470Δ4160Δ21425 and the WT.,C Zheng 2022,2022,3 genes,Zheng C et al 2023 ZrgA contributes to zinc ac,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21134,PHI:123685,,no data found,,,,,,zrgB,,,,,,PHI:123684; PHI:123686,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36482737,PubMed,10.1080/21505594.2022.2156196,Virulence. 2022 Dec 8,zhouxh@sustech.edu.cn,There was no significant difference in the survival rates of mice between the triple mutant Δ1470Δ4160Δ21425 and the WT.,C Zheng 2022,2022,3 genes,Zheng C et al 2023 ZrgA contributes to zinc ac,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21135,PHI:123686,,no data found,,,,,,znuAII,,,,,,PHI:123684; PHI:123685,670,Vibrio parahaemolyticus,223926,RIMD 2210633,gastrointestinal infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36482737,PubMed,10.1080/21505594.2022.2156196,Virulence. 2022 Dec 8,zhouxh@sustech.edu.cn,There was no significant difference in the survival rates of mice between the triple mutant Δ1470Δ4160Δ21425 and the WT.,C Zheng 2022,2022,3 genes,Zheng C et al 2023 ZrgA contributes to zinc ac,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21136,PHI:123687,UniProt,C9ZB67,GenBank,CBG74758,,,87.22,Lrp (SCAB_77931),,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,seedling,leucine-responsive regulatory protein,,,thaxtomin biosynthetic pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36478143,PubMed,10.1111/mpp.13285,Mol Plant Pathol. 2022 Dec 7,liujing9261@ahau.edu.cn,SCAB_Lrp deletion resulted in a dramatic decline in thaxtomin A production and a low-virulence phenotype of S. scabies.,J Liu 2022,2022,1 gene,Liu et al 2023 The leucine-responsive regulato,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21137,PHI:123687,UniProt,C9ZB67,GenBank,CBG74758,,,87.22,Lrp (SCAB_77931),,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,seedling,leucine-responsive regulatory protein,,,thaxtomin biosynthetic pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36478143,PubMed,10.1111/mpp.13285,Mol Plant Pathol. 2022 Dec 7,liujing9261@ahau.edu.cn,SCAB_Lrp deletion resulted in a dramatic decline in thaxtomin A production and a low-virulence phenotype of S. scabies.,J Liu 2022,2022,1 gene,Liu et al 2023 The leucine-responsive regulato,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21138,PHI:123687,UniProt,C9ZB67,GenBank,CBG74758,,,87.22,Lrp (SCAB_77931),,,,,,,1930,Streptomyces scabiei,680198,87.22,common scab (potato),eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,leucine-responsive regulatory protein,,,thaxtomin biosynthetic pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36478143,PubMed,10.1111/mpp.13285,Mol Plant Pathol. 2022 Dec 7,liujing9261@ahau.edu.cn,SCAB_Lrp deletion resulted in a dramatic decline in thaxtomin A production and a low-virulence phenotype of S. scabies.,J Liu 2022,2022,1 gene,Liu et al 2023 The leucine-responsive regulato,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21139,PHI:123688,UniProt,Q04151,GenBank,AAA69859,,,RH,ROP1,,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,rhoptry protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36476844,PubMed,10.1371/journal.ppat.1011021,PLoS Pathog. 2022 Dec 7;18(12):e1011021,moritz.treeck@crick.ac.uk,"PRUΔROP1 parasites are avirulent in vivo; While ROP1 affects the morphology of rhoptries, from where the protein is secreted, it does not affect rhoptry secretion",S Butterworth 2022,2022,2 genes,Butterworth-2022-Toxoplasma gondii virulence f,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21140,PHI:123689,UniProt,S8EUF7,GenBank,EPT26002,,,ME49,KU80,chromosome 11,,,,,,5811,Toxoplasma gondii,1080348,Prugniaud,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36476844,PubMed,10.1371/journal.ppat.1011021,PLoS Pathog. 2022 Dec 7;18(12):e1011021,moritz.treeck@crick.ac.uk,All the PRUΔKU80-infected mice succumbed to infection within 10 days.,S Butterworth 2022,2022,2 genes,Butterworth-2022-Toxoplasma gondii virulence f,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21141,PHI:123690,UniProt,G2X420,GenBank,EGY23319,,,VdLs.17,GAL4 (VDAG_04757),chromosome 3,,,,,,27337,Verticillium dahliae,,Vd080,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Jimian 11,,,stem; leaf,alpha-galactosidase gene,,,,reduced virulence,,,,,,reduced,,wild type,reduced,no,SDS; CR; sorbitol; KCl; NaCl,sodium dodecyl sulfate (SDS): CHEBI:8984; congo red: CHEBI:34653; sorbitol: CHEBI:30911; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,NN,36475739,PubMed,10.1128/spectrum.03515-22,Microbiol Spectr. 2022 Dec 7;e0351522,heqinanyang@163.com,Deletion of VdGAL4 reduced the conidial yield and conidial germination rate of V. dahliae; VdGAL4 deletion mutants exhibited reduced pathogenicity of V. dahliae.,Y Wen 2022,2022,1 gene,Wen et al 2023 spectrum.03515-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21142,PHI:123691,UniProt,Q86L95,GenBank,AAO49745,,,RH,wx2,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,,,,pyroptosis pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36471417,PubMed,10.1186/s13071-022-05502-5,Parasit Vectors. 2022 Dec 5;15(1):454,wuxiang@csu.edu.cn,"Compared with the wild RH and RHwx2+/+ strain groups, the survival time for mice infected with the RHwx2−/− strain was prolonged to a certain extent.",Z Ma 2022,2022,1 gene,Ma-2022-Virulence-related gene wx2 of Toxoplas,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21143,PHI:123692,UniProt,P0C0H0,GenBank,AAA17725,,,WF14,hasA,,,,,,,1314,Streptococcus pyogenes,186103,MGAS8232,infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,skin; lung; liver; kidney; sleen; heart; nasal mucosa,hyaluronate synthase,,,,reduced virulence,,,,,reduced lesions,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36449535,PubMed,10.1371/journal.ppat.1011013,PLoS Pathog. 2022 Nov 30;18(11):e1011013,john.mccormick@uwo.ca,The ΔhasA mutant strain revealed a clear reduction in virulence through considerably smaller lesions and less inflamed tissue over the infection period compared to wildtype-infected mice.,J R Hurst 2022,2022,1 gene,Hurst-2022-The Streptococcus pyogenes hyaluron,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21144,PHI:123693,UniProt,G4MZL5,GenBank,EHA54574,,,70-15,MoCsn6,chromosome 2,,,MoAtg6,UniProt: A0A4V1C6M5; GenBank: QBZ60408,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,COP9 signalosome,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced; defective,reduced,no,sorbitol; KCl; NaCl,sorbitol: CHEBI:30911; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,NN,36445131,PubMed,10.1128/spectrum.02020-22,Microbiol Spectr. 2022 Dec 21;10(6):e0202022,xhliu@zju.edu.cn,"ΔMocsn6 mutants showed a significantly reduced growth rate, sporulation rate, and germ tube germination rate; Pathogenicity assays showed that the ΔMocsn6 mutant significantly reduced the number of disease spots on isolated leaves.",Z-F Shen 2022,2022,1 gene,Shen et al 2023 spectrum.02020-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21145,PHI:123693,UniProt,G4MZL5,GenBank,EHA54574,,,70-15,MoCsn6,chromosome 2,,,MoAtg6,UniProt: A0A4V1C6M5; GenBank: QBZ60408,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,COP9 signalosome,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced; defective,reduced,no,sorbitol; KCl; NaCl,sorbitol: CHEBI:30911; KCl: CHEBI:32588; NaCl: CHEBI:26710,,,,,gene deletion: full; gene complementation,,,NN,36445131,PubMed,10.1128/spectrum.02020-22,Microbiol Spectr. 2022 Dec 21;10(6):e0202022,xhliu@zju.edu.cn,"ΔMocsn6 mutants showed a significantly reduced growth rate, sporulation rate, and germ tube germination rate; Pathogenicity assays showed that the ΔMocsn6 mutant significantly reduced the number of disease spots on isolated leaves.",Z-F Shen 2022,2022,1 gene,Shen et al 2023 spectrum.02020-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21146,PHI:123694,UniProt,A0A1D8PEY6,GenBank,AOW26695,,,SC5314,tcb1,chromosome 1,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,tricalbin-encoding gene,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36445092,PubMed,10.1128/spectrum.02079-22,Microbiol Spectr. 2022 Dec 21;10(6):e0207922,yuqilin@mail.nankai.edu.cn,"Deletion of the TCB genes decreased secretion of extracellular aspartyl proteinases, reduced transport of the cell wall protein Hwp1 from the cytoplasm to the cell wall, and attenuated virulence of the fungal pathogen.",L Yang 2022,2022,2 genes,Yang et al 2023 spectrum.02079-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21147,PHI:123695,UniProt,A0A1D8PCX0,GenBank,AOW25991,,,SC5314,tcb3,chromosome 1,,,,,,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,tricalbin-encoding gene,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36445092,PubMed,10.1128/spectrum.02079-22,Microbiol Spectr. 2022 Dec 21;10(6):e0207922,yuqilin@mail.nankai.edu.cn,"Deletion of the TCB genes decreased secretion of extracellular aspartyl proteinases, reduced transport of the cell wall protein Hwp1 from the cytoplasm to the cell wall, and attenuated virulence of the fungal pathogen.",L Yang 2022,2022,2 genes,Yang et al 2023 spectrum.02079-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21148,PHI:123694,UniProt,A0A1D8PEY6,GenBank,AOW26695,,,SC5314,tcb1,chromosome 1,,,,,PHI:123695,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,tricalbin-encoding gene,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36445092,PubMed,10.1128/spectrum.02079-22,Microbiol Spectr. 2022 Dec 21;10(6):e0207922,yuqilin@mail.nankai.edu.cn,"Deletion of the TCB genes decreased secretion of extracellular aspartyl proteinases, reduced transport of the cell wall protein Hwp1 from the cytoplasm to the cell wall, and attenuated virulence of the fungal pathogen.",L Yang 2022,2022,2 genes,Yang et al 2023 spectrum.02079-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21149,PHI:123695,UniProt,A0A1D8PCX0,GenBank,AOW25991,,,SC5314,tcb3,chromosome 1,,,,,PHI:123694,5476,Candida albicans,,BWP17,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,tricalbin-encoding gene,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36445092,PubMed,10.1128/spectrum.02079-22,Microbiol Spectr. 2022 Dec 21;10(6):e0207922,yuqilin@mail.nankai.edu.cn,"Deletion of the TCB genes decreased secretion of extracellular aspartyl proteinases, reduced transport of the cell wall protein Hwp1 from the cytoplasm to the cell wall, and attenuated virulence of the fungal pathogen.",L Yang 2022,2022,2 genes,Yang et al 2023 spectrum.02079-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21150,PHI:123696,UniProt,no data found,GenBank,CAZ52647,,,SC84,apuA,,,,,,,1307,Streptococcus suis,,SC19,meningitis; septicemia; arthritis; pneumonia (pig),moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,amylopullulanase,,,carbon metabolism pathway,reduced virulence,,,,,,,,increased,,no,glycogen; glucose,glycogen: CHEBI:28087; glucose: CHEBI:17234,,,,,gene deletion: full,,,NN,36439226,PubMed,10.3389/fcimb.2022.938286,Front Cell Infect Microbiol. 2022 Nov 9;12:938286,zengyb2004@163.com,The livability of the ΔapuA strain grown in glycogen was significantly higher than that of the WT strain grown in glycogen both in the high and low dose groups. The livability of the ΔapuA strain grown in glucose was significantly higher than that of the WT strain grown in glucose in the low dose group.,M-F Tan 2022,2022,1 gene,Tan et al 2023 fcimb-12-938286,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21151,PHI:123697,UniProt,A0A7L9MBE5,GenBank,QOK63853,,,CVI_72,BtpB,chromosome 1,,,,,,29461,Brucella suis,,S2,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,,effector protein,,,autophagy pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36430916,PubMed,10.3390/ijms232214439,Int J Mol Sci. 2022 Nov 20;23(22):14439,wangaihua@nwafu.edu.cn,"An isogenic mutant strain, ΔbtpB, inhibited apoptosis compared to the wild-type strain B. suis S2 in RAW264.7 cells.",J Li 2022,2022,1 gene,Li-2022-Brucella BtpB Manipulates Apoptosis an,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21152,PHI:123698,UniProt,A0A0H3K5Z1,GenBank,ATC66507,,,NYU_Newman,sapS (NWMN_0249),,,,,,,1280,Staphylococcus aureus,,SA564,pneumonia,bony fishes,7955,Danio rerio (related: zebrafish),GAB line,,,embryo,acid phosphatase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36430506,PubMed,10.3390/ijms232214031,Int J Mol Sci. 2022 Nov 14;23(22):14031,virginie.molle@umontpellier,The SA564 ΔsapS mutant demonstrated a significantly lower pathogenicity in a zebrafish infection model.,N Ahmad 2022,2022,1 gene,Ahmad-Mansour-2022-Characterization of the Sec,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21153,PHI:123698,UniProt,A0A0H3K5Z1,GenBank,ATC66507,,,NYU_Newman,sapS (NWMN_0249),,,,,,,1280,Staphylococcus aureus,,SA564,pneumonia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; kidney,acid phosphatase,,,,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36430506,PubMed,10.3390/ijms232214031,Int J Mol Sci. 2022 Nov 14;23(22):14031,virginie.molle@umontpellier,SA564ΔsapS mutant demonstrated a significantly lower bacterial burden in liver and renal tissues of mice at four days post infection in comparison to the wild type.,N Ahmad 2022,2022,1 gene,Ahmad-Mansour-2022-Characterization of the Sec,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21154,PHI:123699,UniProt,no data found,GenBank,,,,,Smi1,,,,,,,282267,Fusarium asiaticum,,2021,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhenmai 22,,,spikelet,regulatory protein,,,,reduced virulence,,,,,,reduced; defective,,reduced; defective,reduced,no,NaCl; KCl; Congo red; caffeine; SDS; H2O2; menadione,NaCl: CHEBI:26710; KCl: CHEBI:32588; Congo red: CHEBI:34653; caffeine: CHEBI:27732; SDS: CHEBI:8984; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,NN,36422010,PubMed,10.3390/jof8111189,J Fungi (Basel). 2022 Nov 11;8(11):1189,20170058@zafu.edu.cn,"The deletion of FaSmi1 leads to defects in mycelial growth, asexual reproduction, and virulence.",Y Zhang 2022,2022,1 gene,Zhang-2022-FaSmi1 Is Essential for the Vegetat,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21155,PHI:123699,UniProt,no data found,GenBank,,,,,Smi1,,,,,,,282267,Fusarium asiaticum,,2021,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,stigma,regulatory protein,,,,loss of pathogenicity,,,,,,reduced; defective,,reduced; defective,reduced,no,NaCl; KCl; Congo red; caffeine; SDS; H2O2; menadione,NaCl: CHEBI:26710; KCl: CHEBI:32588; Congo red: CHEBI:34653; caffeine: CHEBI:27732; SDS: CHEBI:8984; H2O2: CHEBI:16240; menadione: CHEBI:28869,,,,,gene deletion: full; gene complementation,,,NN,36422010,PubMed,10.3390/jof8111189,J Fungi (Basel). 2022 Nov 11;8(11):1189,20170058@zafu.edu.cn,"The deletion of FaSmi1 leads to defects in mycelial growth, asexual reproduction, and virulence.",Y Zhang 2022,2022,1 gene,Zhang-2022-FaSmi1 Is Essential for the Vegetat,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21156,PHI:123700,UniProt,A0A0H2ZGV0,GenBank,,,,,colR (PALES_47611),,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,regulatory protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36424517,PubMed,10.1038/s41396-022-01343-3,ISME J. 2022 Nov 24,cara.haney@ubc.ca,Significantly smaller abscess than wild-type LESB58 (54% reduction in size; 90 ± 9 mm for wild-type versus 48.6 ± 3 mM for the ΔcolR mutant).,C L Wiesmann 2022,2022,5 genes,Wiesmann-2022-The ColR_S two-component system,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21157,PHI:123701,UniProt,Q9HXC7,GenBank,,,,,tpbA (PALES_14321),,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,tyrosine phosphatase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36424517,PubMed,10.1038/s41396-022-01343-3,ISME J. 2022 Nov 24,cara.haney@ubc.ca,Deletion of the P.aeruginosa LESB58 ortholog of the gene resulted in decreased virulence in the abscess model; Deletion of tpbA led to a small but significant decrease in bacterial recovery in three days post-infection.,C L Wiesmann 2022,2022,5 genes,Wiesmann-2022-The ColR_S two-component system,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21158,PHI:123702,UniProt,Q9HY23,GenBank,,,,,dgkA (PALES_47610),,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,diacyl glycerol kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36424517,PubMed,10.1038/s41396-022-01343-3,ISME J. 2022 Nov 24,cara.haney@ubc.ca,Deletion of the P.aeruginosa LESB58 ortholog of the gene resulted in decreased virulence in the abscess model; Deletion of dgkA led to bacterial recovery in three days post-infection.,C L Wiesmann 2022,2022,5 genes,Wiesmann-2022-The ColR_S two-component system,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21159,PHI:123703,UniProt,Q9I6U4,GenBank,,,,,pap2 (PALES_10931),,,,,,,287,Pseudomonas aeruginosa,557722,LESB58,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,phosphatidic acid phosphatases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36424517,PubMed,10.1038/s41396-022-01343-3,ISME J. 2022 Nov 24,cara.haney@ubc.ca,Deletion of the P.aeruginosa LESB58 ortholog of the gene resulted in decreased virulence in the abscess model; Deletion of pap2 led to a small but significant decrease in bacterial recovery in three days post-infection.,C L Wiesmann 2022,2022,5 genes,Wiesmann-2022-The ColR_S two-component system,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21160,PHI:123704,UniProt,Q9HW83,GenBank,AAG07706,,,PAO1,colR (PA4318),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,regulatory protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36424517,PubMed,10.1038/s41396-022-01343-3,ISME J. 2022 Nov 24,cara.haney@ubc.ca,ΔcolR mutant did not have a pronounced virulence defect.,C L Wiesmann 2022,2022,5 genes,Wiesmann-2022-The ColR_S two-component system,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21161,PHI:123705,UniProt,G4NFI3,GenBank,EHA46790,,,70-15,PYR4 (XM_003719109),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Ina-86-137,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Sachikaze,,,leaf,class II dihydroorotate dehydrogenase,,,de novo pathway,reduced virulence,,,,,no necrotic lesions,,,reduced; defective,,no,,,,,,,gene deletion: full,,,NN,36514691,PubMed,10.1584/jpestics.D22-027,J Pestic Sci. 2022 Nov 20;47(4):190-196,Norikazu.higashimura@mitsuichemicals.com,"Necrotic lesions appeared on rice plant leaves inoculated with wildtype Ina-86-137, whereas no such lesions appeared on rice plant leaves inoculated with ΔPopyr4 mutant.",N Higashimura 2022,2022,1 gene,Higashimura-2022-The target site of the novel,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21162,PHI:123706,UniProt,A0A0C6DV29,GenBank,BAQ25926,,,OC3,rinA,,,,,,,1280,Staphylococcus aureus,93061,NCTC8325,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,tanscription activator,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36520268,PubMed,10.1007/s13258-022-01352-8,Genes Genomics. 2022 Dec 15,lyj2020@ustc.edu.cn,The fatality rate of G. mellonella larvae injected with the wild-type and complementation strains were significantly higher than rinA mutant strain.,M Jiang 2022,2022,2 genes,Jiang-2022-Phage transcription activator RinA,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21163,PHI:123706,UniProt,A0A0C6DV29,GenBank,BAQ25926,,,OC3,rinA,,,,,,,1280,Staphylococcus aureus,93061,NCTC8325,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,tanscription activator,,,,reduced virulence,,,,,lower skin lesions,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36520268,PubMed,10.1007/s13258-022-01352-8,Genes Genomics. 2022 Dec 15,lyj2020@ustc.edu.cn,"Compared with the wild-type and complementation strains, the subcutaneous abscess area of mice inoculated with the rinA mutant strain was significantly reduced.",M Jiang 2022,2022,2 genes,Jiang-2022-Phage transcription activator RinA,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21164,PHI:123707,UniProt,Q2G2U9,GenBank,AAA62477,,,RN450,sarA,,,,,,,1280,Staphylococcus aureus,93061,NCTC8325,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,tanscription activator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36520268,PubMed,10.1007/s13258-022-01352-8,Genes Genomics. 2022 Dec 15,lyj2020@ustc.edu.cn,Survival of larvae reduced when infected with sarA deletion mutant.,M Jiang 2022,2022,2 genes,Jiang-2022-Phage transcription activator RinA,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21165,PHI:123706,UniProt,A0A0C6DV29,GenBank,BAQ25926,,,OC3,rinA,,,,,,PHI:123707,1280,Staphylococcus aureus,93061,NCTC8325,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,tanscription activator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36520268,PubMed,10.1007/s13258-022-01352-8,Genes Genomics. 2022 Dec 15,lyj2020@ustc.edu.cn,Survival of larvae reduced when infected with sarA/rinA deletion mutant.,M Jiang 2022,2022,2 genes,Jiang-2022-Phage transcription activator RinA,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21166,PHI:123707,UniProt,Q2G2U9,GenBank,AAA62477,,,RN450,sarA,,,,,,PHI:123706,1280,Staphylococcus aureus,93061,NCTC8325,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,tanscription activator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36520268,PubMed,10.1007/s13258-022-01352-8,Genes Genomics. 2022 Dec 15,lyj2020@ustc.edu.cn,Survival of larvae reduced when infected with sarA/rinA deletion mutant.,M Jiang 2022,2022,2 genes,Jiang-2022-Phage transcription activator RinA,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21167,PHI:123708,UniProt,S7W1J6,GenBank,EPR58928,,,GT1,CBDP1 (TGGT1_315520),,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,calcium-binding egf domain-containing proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36471092,PubMed,10.1007/s00436-022-07739-6,Parasitol Res. 2022 Dec 6,wangmeng02@caas.cn,CBDP mutants did not exhibit any significant attenuated virulence compared to the wild-type strain in mice.,X-C Wang 2022,2022,4 genes,Wang-2022-Effect of deleting four Toxoplasma g,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21168,PHI:123709,UniProt,S7UKB1,GenBank,EPR58185,,,GT1,CBDP2 (TGGT1_318540),,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,calcium-binding egf domain-containing proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36471092,PubMed,10.1007/s00436-022-07739-6,Parasitol Res. 2022 Dec 6,wangmeng02@caas.cn,CBDP mutants did not exhibit any significant attenuated virulence compared to the wild-type strain in mice.,X-C Wang 2022,2022,4 genes,Wang-2022-Effect of deleting four Toxoplasma g,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21169,PHI:123710,UniProt,S7WD44,GenBank,EPR64714,,,GT1,CBDP3 (TGGT1_269930),,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,calcium-binding egf domain-containing proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36471092,PubMed,10.1007/s00436-022-07739-6,Parasitol Res. 2022 Dec 6,wangmeng02@caas.cn,CBDP mutants did not exhibit any significant attenuated virulence compared to the wild-type strain in mice.,X-C Wang 2022,2022,4 genes,Wang-2022-Effect of deleting four Toxoplasma g,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21170,PHI:123711,UniProt,A0A125YSW7,GenBank,EPR58931,,,GT1,CBDP4 (TGGT1_315550),,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,,calcium-binding egf domain-containing proteins,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36471092,PubMed,10.1007/s00436-022-07739-6,Parasitol Res. 2022 Dec 6,wangmeng02@caas.cn,CBDP mutants did not exhibit any significant attenuated virulence compared to the wild-type strain in mice.,X-C Wang 2022,2022,4 genes,Wang-2022-Effect of deleting four Toxoplasma g,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21171,PHI:123712,UniProt,G4MSA5,GenBank,EHA58363,,,70-15,Mosrp1 (MGG_04482),chromosome 1,,,MoRnps1 (MGG_02580); MoThoc1 (MGG_04399); MoGrp1 (MGG_07511),UniProt: G4NJU7; GenBank: EHA46476; UniProt: G4MKM1; GenBank: EHA58404; UniProt: G4N1P5; Gen,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,serine/arginine-rich (SR) protein,,,,reduced virulence,,,,,tiny lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36480554,PubMed,10.1371/journal.ppat.1011036,PLoS Pathog. 2022 Dec 8;18(12):e1011036,pengyl@cau.edu.cn,The phenotypic assay showed that vegetative mycelial growth of srp1ko1 was significantly reduced compared to that of P131; srp1ko1 produced only tiny lesions on the leaves of seedlings of rice.,W Shi 2022,2022,3 genes,Shi-2022-The rice blast fungus SR protein 1 re,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21172,PHI:123712,UniProt,G4MSA5,GenBank,EHA58363,,,70-15,Mosrp1 (MGG_04482),chromosome 1,,,MoRnps1 (MGG_02580); MoThoc1 (MGG_04399); MoGrp1 (MGG_07511),UniProt: G4NJU7; GenBank: EHA46476; UniProt: G4MKM1; GenBank: EHA58404; UniProt: G4N1P5; Gen,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,serine/arginine-rich (SR) protein,,,,reduced virulence,,,,,tiny lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36480554,PubMed,10.1371/journal.ppat.1011036,PLoS Pathog. 2022 Dec 8;18(12):e1011036,pengyl@cau.edu.cn,The phenotypic assay showed that vegetative mycelial growth of srp1ko1 was significantly reduced compared to that of P131; srp1ko1 produced only tiny lesions on the leaves of seedlings of barley.,W Shi 2022,2022,3 genes,Shi-2022-The rice blast fungus SR protein 1 re,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21173,PHI:123713,UniProt,G4MZM4,GenBank,EHA55388,,,70-15,Moatf1 (MGG_08212),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,transcription factor,,,,reduced virulence,,,,,tiny lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36480554,PubMed,10.1371/journal.ppat.1011036,PLoS Pathog. 2022 Dec 8;18(12):e1011036,pengyl@cau.edu.cn,"Phenotypic analysis showed that the ΔMoatf1 mutant exhibited defects on colony growth, conidiation, and virulence.",W Shi 2022,2022,3 genes,Shi-2022-The rice blast fungus SR protein 1 re,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21174,PHI:123714,UniProt,G4N1K3,GenBank,EHA53270,,,70-15,Momtp1(MGG_07843),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,transporter protein,,,,reduced virulence,,,,,tiny lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36480554,PubMed,10.1371/journal.ppat.1011036,PLoS Pathog. 2022 Dec 8;18(12):e1011036,pengyl@cau.edu.cn,"Phenotypic analysis showed that the ΔMomtp1 mutant exhibited defects on colony growth, conidiation, and virulence.",W Shi 2022,2022,3 genes,Shi-2022-The rice blast fungus SR protein 1 re,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21175,PHI:123712,UniProt,G4MSA5,GenBank,EHA58363,,,70-15,Mosrp1 (MGG_04482),chromosome 1,MoSrpΔ1–90,,MoRnps1 (MGG_02580); MoThoc1 (MGG_04399); MoGrp1 (MGG_07511),UniProt: G4NJU7; GenBank: EHA46476; UniProt: G4MKM1; GenBank: EHA58404; UniProt: G4N1P5; Gen,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,serine/arginine-rich (SR) protein,,,,reduced virulence,,,,,tiny lesions,reduced,,reduced,,no,Congo red (CR); calcofluor white (CFW); sorbitol,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; D-sorbitol: CHEBI:17924,,,,,gene deletion: partial; gene complementation,,,NN,36480554,PubMed,10.1371/journal.ppat.1011036,PLoS Pathog. 2022 Dec 8;18(12):e1011036,pengyl@cau.edu.cn,MoSrpΔ1–90 (cSRPΔ91-206) transformants exhibited similar mycelial growth and virulence as srp1ko1.,W Shi 2022,2022,3 genes,Shi-2022-The rice blast fungus SR protein 1 re,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21176,PHI:123712,UniProt,G4MSA5,GenBank,EHA58363,,,70-15,Mosrp1 (MGG_04482),chromosome 1,MoSrpΔ91–206,,MoRnps1 (MGG_02580); MoThoc1 (MGG_04399); MoGrp1 (MGG_07511),UniProt: G4NJU7; GenBank: EHA46476; UniProt: G4MKM1; GenBank: EHA58404; UniProt: G4N1P5; Gen,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,serine/arginine-rich (SR) protein,,,,reduced virulence,,,,,tiny lesions,reduced,,reduced,,no,Congo red (CR); calcofluor white (CFW); sorbitol,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; D-sorbitol: CHEBI:17924,,,,,gene deletion: partial; gene complementation,,,NN,36480554,PubMed,10.1371/journal.ppat.1011036,PLoS Pathog. 2022 Dec 8;18(12):e1011036,pengyl@cau.edu.cn,cSRPΔ1-90 transformants were similar to srp1ko1 in virulence and restored the capacities on colony growth and conidiation,W Shi 2022,2022,3 genes,Shi-2022-The rice blast fungus SR protein 1 re,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21177,PHI:123712,UniProt,G4MSA5,GenBank,EHA58363,,,70-15,Mosrp1 (MGG_04482),chromosome 1,MoSrpΔ1–130,,MoRnps1 (MGG_02580); MoThoc1 (MGG_04399); MoGrp1 (MGG_07511),UniProt: G4NJU7; GenBank: EHA46476; UniProt: G4MKM1; GenBank: EHA58404; UniProt: G4N1P5; Gen,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,serine/arginine-rich (SR) protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,Congo red (CR); calcofluor white (CFW); sorbitol,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; D-sorbitol: CHEBI:17924,,,,,gene deletion: partial; gene complementation,,,NN,36480554,PubMed,10.1371/journal.ppat.1011036,PLoS Pathog. 2022 Dec 8;18(12):e1011036,pengyl@cau.edu.cn,"MoSrpΔ1-130 (cSRPΔ1-130), exhibited the wild-type phenotypes on colony growth, conidiation, and virulence.",W Shi 2022,2022,3 genes,Shi-2022-The rice blast fungus SR protein 1 re,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21178,PHI:123712,UniProt,G4MSA5,GenBank,EHA58363,,,70-15,Mosrp1 (MGG_04482),chromosome 1,M117 (serine to alanine),,MoRnps1 (MGG_02580); MoThoc1 (MGG_04399); MoGrp1 (MGG_07511),UniProt: G4NJU7; GenBank: EHA46476; UniProt: G4MKM1; GenBank: EHA58404; UniProt: G4N1P5; Gen,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,serine/arginine-rich (SR) protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,Congo red (CR); calcofluor white (CFW); sorbitol,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; D-sorbitol: CHEBI:17924,,,,,gene mutation; gene complementation,,,NN,36480554,PubMed,10.1371/journal.ppat.1011036,PLoS Pathog. 2022 Dec 8;18(12):e1011036,pengyl@cau.edu.cn,"M117 exhibited the wild-type phenotypes on colony growth, conidiation, and plant infection.",W Shi 2022,2022,3 genes,Shi-2022-The rice blast fungus SR protein 1 re,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21179,PHI:123712,UniProt,G4MSA5,GenBank,EHA58363,,,70-15,Mosrp1 (MGG_04482),chromosome 1,M119 (serine to alanine),,MoRnps1 (MGG_02580); MoThoc1 (MGG_04399); MoGrp1 (MGG_07511),UniProt: G4NJU7; GenBank: EHA46476; UniProt: G4MKM1; GenBank: EHA58404; UniProt: G4N1P5; Gen,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,serine/arginine-rich (SR) protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,Congo red (CR); calcofluor white (CFW); sorbitol,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; D-sorbitol: CHEBI:17924,,,,,gene mutation; gene complementation,,,NN,36480554,PubMed,10.1371/journal.ppat.1011036,PLoS Pathog. 2022 Dec 8;18(12):e1011036,pengyl@cau.edu.cn,"M119 exhibited the wild-type phenotypes on colony growth, conidiation, and plant infection.",W Shi 2022,2022,3 genes,Shi-2022-The rice blast fungus SR protein 1 re,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21180,PHI:123712,UniProt,G4MSA5,GenBank,EHA58363,,,70-15,Mosrp1 (MGG_04482),chromosome 1,M117 (serine to alanine)/M119 (serine to alanine) double mutant,,MoRnps1 (MGG_02580); MoThoc1 (MGG_04399); MoGrp1 (MGG_07511),UniProt: G4NJU7; GenBank: EHA46476; UniProt: G4MKM1; GenBank: EHA58404; UniProt: G4N1P5; Gen,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,serine/arginine-rich (SR) protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,Congo red (CR); calcofluor white (CFW); sorbitol,congo red: CHEBI:34653; calcofluor white: CHEBI:50011; D-sorbitol: CHEBI:17924,,,,,gene mutation; gene complementation,,,NN,36480554,PubMed,10.1371/journal.ppat.1011036,PLoS Pathog. 2022 Dec 8;18(12):e1011036,pengyl@cau.edu.cn,"M117/M119, exhibited the wild-type phenotypes on colony growth, conidiation, and plant infection.",W Shi 2022,2022,3 genes,Shi-2022-The rice blast fungus SR protein 1 re,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21181,PHI:123715,UniProt,G4YIB3,GenBank,OL848976,,,P6497,PsFYVE1,,,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. William 82,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,36461945,PubMed,10.1093/plphys/kiac552,Plant Physiol. 2022 Dec 3;kiac552,shendanyu@njau.edu.cn,Virulence of the PsFYVE1-silenced transformants decreased significantly compared with that of the WT strain. PsFYVE1 can impair plant defense and promote P. capsici infection.,X Lu 2022,2022,1 gene,Lu-2022-The Phytophthora sojae effector PsFYVE,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21182,PHI:123715,UniProt,G4YIB3,GenBank,OL848976,,,P6497,PsFYVE1,,,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants; gene deletion: partial,,,NN,36461945,PubMed,10.1093/plphys/kiac552,Plant Physiol. 2022 Dec 3;kiac552,shendanyu@njau.edu.cn,"Expression of PsFYVE1-GFP in N. benthamiana significantly promoted P. capsici infection, compared with the GFP control. FIST_C deletion mutant did not enhance N. benthamiana susceptibility to P. capsici,but its protein accumulation level was decreased substantially. FIST_C deletion mutant did not enhance N. benthamiana susceptibility, and protein expression was stable.",X Lu 2022,2022,1 gene,Lu-2022-The Phytophthora sojae effector PsFYVE,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21183,PHI:123716,UniProt,Q1KSE7,GenBank,ABE76510,,,RH,PGK2,chromosome 11,,,,,,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,phosphoglycerate kinase 2,,,metabolic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36449552,PubMed,10.1371/journal.ppat.1011009,PLoS Pathog. 2022 Nov 30;18(11):e1011009,shenbang@mail.hzau.edu.cn,Virulence of the Δpgk2 mutant in mice is also similar to that of the wildtype strain.,Z Niu 2022,2022,2 genes,Niu-2022-Two apicoplast dwelling glycolytic en,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21184,PHI:123716,UniProt,Q1KSE7,GenBank,ABE76510,,,RH,PGK2,chromosome 11,,,,,PHI:123718,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,phosphoglycerate kinase 2,,,metabolic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36449552,PubMed,10.1371/journal.ppat.1011009,PLoS Pathog. 2022 Nov 30;18(11):e1011009,shenbang@mail.hzau.edu.cn,"Δpgk2-Δpyk2 strains displayed very similar survival plots, indicating that simultaneous inactivation of PGK2 and PYK2 had no influence on acute virulence of the parasites .",Z Niu 2022,2022,2 genes,Niu-2022-Two apicoplast dwelling glycolytic en,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21185,PHI:123717,UniProt,A0A125YUJ7,GenBank,,,,,PYK2,,,,,,PHI:123717,5811,Toxoplasma gondii,383379,RH,acute toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,pyruvate kinase2,,,metabolic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36449552,PubMed,10.1371/journal.ppat.1011009,PLoS Pathog. 2022 Nov 30;18(11):e1011009,shenbang@mail.hzau.edu.cn,"Δpgk2-Δpyk2 strains displayed very similar survival plots, indicating that simultaneous inactivation of PGK2 and PYK2 had no influence on acute virulence of the parasites .",Z Niu 2022,2022,2 genes,Niu-2022-Two apicoplast dwelling glycolytic en,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21186,PHI:123718,UniProt,A1TRR1,GenBank,ABM33649,,,AAC00-1,AopV (Aave_3085),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Ruixin,,,leaf,effector protein,,,PTI pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36233021,PubMed,10.3390/ijms231911719,Int J Mol Sci. 2022 Oct 3;23(19):11719,tczhao@ippcaas.cn,AopV affected the host immune responses by stimulating JA (plant hormone) in Watermelon.,J Jiang 2022,2022,1 gene,Jiang-2022-Acidovorax citrulli Effector AopV S,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21187,PHI:123718,UniProt,A1TRR1,GenBank,ABM33649,,,AAC00-1,AopV (Aave_3085),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,PTI pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36233021,PubMed,10.3390/ijms231911719,Int J Mol Sci. 2022 Oct 3;23(19):11719,tczhao@ippcaas.cn,AopV inhibited the PTI pathway by inhibiting the production of ROS in N. benthamiana.,J Jiang 2022,2022,1 gene,Jiang-2022-Acidovorax citrulli Effector AopV S,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21188,PHI:123718,UniProt,A1TRR1,GenBank,ABM33649,,,AAC00-1,AopV (Aave_3085),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,PTI pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,NN,36233021,PubMed,10.3390/ijms231911719,Int J Mol Sci. 2022 Oct 3;23(19):11719,tczhao@ippcaas.cn,AopV inhibited the PTI response induced by Pst D36E and enhanced Pst D36E's colonization of N. benthamiana.,J Jiang 2022,2022,1 gene,Jiang-2022-Acidovorax citrulli Effector AopV S,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21189,PHI:123719,UniProt,A1TNV7,GenBank,ABM32645,,,AAC00-1,BarA (Aave_2063),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 6,,,seedling,histidine kinase,,,,increased virulence (hypervirulence),,,,,,,,,,no,kanamycin; ampicillin,kanamycin: CHEBI:6104; ampicillin: CHEBI:28971,,,,,gene deletion: full; gene complementation; gene mutation: characterised,,,NN,36532489,PubMed,10.3389/fmicb.2022.1064577,Front Microbiol. 2022 Nov 30;13:1064577,yangyuwen@126.com,The disease index of the mutant strain ΔbarAAc-pB (mean = 43.83) was significantly higher than WT-pB (mean = 17.51).,P Qiao 2022,2022,1 gene,Qiao et al 2023 fmicb-13-1064577,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21190,PHI:123720,UniProt,A1TME9,GenBank,ABM32137,,,AAC00-1,AopN (Aave_1548),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,PTI pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation; functional test in host: transient expression,,,NN,32842656,PubMed,10.3390/ijms21176050,Int J Mol Sci. 2020 Aug 22;21(17):6050,zhangxiao0719@126.com,AopN mutant showed significantly reduced virulence in the infevted leaves of N. benthamiana compared with the WT strain.,X Zhang 2022,2022,1 gene,Zhang-2020-Identification and Functional Analy,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21191,PHI:123720,UniProt,A1TME9,GenBank,ABM32137,,,AAC00-1,AopN (Aave_1548),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Ruixin,,,seedling; leaf,effector protein,,,PTI pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; functional test in host: transient expression,,,NN,32842656,PubMed,10.3390/ijms21176050,Int J Mol Sci. 2020 Aug 22;21(17):6050,zhangxiao0719@126.com,The aopN mutant did not significantly reduce the virulence in watermelon cotyledons compared to the WT and its complemented strain.,X Zhang 2022,2022,1 gene,Zhang-2020-Identification and Functional Analy,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21192,PHI:123721,UniProt,A1TTW1,GenBank,ABM34399,,,AAC00-1,GlpdAc,,,,,,,80869,Paracidovorax citrulli,,KACC17005,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),,,,seedling; leaf,glycerol-3-phosphate dehydrogenase,,,carbohydrate metabolism,loss of pathogenicity,,,,,,,,,,no,NaCl; ciprofloxacin,NaCl: CHEBI:26710; ciprofloxacin: CHEBI:100241,,,,,gene deletion: full; gene complementation,,,NN,33551695,PubMed,10.5423/PPJ.OA.12.2020.0221,Plant Pathol J. 2021 Feb 1;37(1):36-46,sangjlee@cau.ac.kr,"AcΔglpdAc(EV) did not cause disease, with a disease index 0 at 7 DAI.",M Kim 2022,2022,1 gene,Kim-2021-Proteomic and Phenotypic Analyses of,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21193,PHI:123722,UniProt,A1TLJ0,GenBank,ATG95109,,,KACC17005,PpdaAc,,,,,,,80869,Paracidovorax citrulli,,,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),,,,seedling; leaf,pyridoxal phosphate-dependent aminotransferase,,,glyoxylate pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,34897258,PubMed,10.5423/PPJ.NT.09.2021.0139,Plant Pathol J. 2021 Dec;37(6):673-680,swhan@cau.ac.kr,ppdaAc knockout mutant had a significantly reduced virulence in watermelon.,J Lee 2022,2022,1 gene,Lee-2021-Comparative Proteomic Analysis for a,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21194,PHI:123723,UniProt,A1TSA4,GenBank,ABM33842,,,AAC00-1,CmpAc,,,,,,,80869,Paracidovorax citrulli,,KACC17005,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),,,,seedling; leaf,chorismate mutase/prephenate dehydratase,,,shikimate pathway,loss of pathogenicity,,,,,,,,,,no,polymyxin B,polymyxin B: CHEBI:8309,,,,,gene deletion: full; gene complementation,,,NN,33101336,PubMed,10.3389/fpls.2020.569552,Front Plant Sci. 2020 Sep 25;11:569552,swhan@cau.ac.kr,"Ac strain lacking CmpAc, AcΔcmpAc(EV), were significantly less virulent on watermelon in the germinatedseed inoculation and leaf infiltration assays.",M Kim 2022,2022,1 gene,Kim-2020-Putative Bifunctional Chorismate Muta,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21195,PHI:123724,UniProt,A0A384JYH5,GenBank,ATZ55630,,,B05.10,BcXyr1,chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,reduced virulence,,,,,reduced,reduced,,reduced,reduced,no,Congo red (CR); H2O2,congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Deletion of the bcxyr1 gene led to impaired spore germination and reduced fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21196,PHI:123724,UniProt,A0A384JYH5,GenBank,ATZ55630,,,B05.10,BcXyr1,chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,increased virulence (hypervirulence),,,,,increased,increased,,increased,increased,no,Congo red (CR); H2O2,congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Overexpression of the bcxyr1 gene led to impaired spore germination and increase fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21197,PHI:123724,UniProt,A0A384JYH5,GenBank,ATZ55630,,,B05.10,BcXyr1,chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,reduced virulence,,,,,reduced,reduced,,reduced,reduced,no,Congo red (CR); H2O2,congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Deletion of the bcxyr1 gene led to impaired spore germination and reduced fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21198,PHI:123724,UniProt,A0A384JYH5,GenBank,ATZ55630,,,B05.10,BcXyr1,chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,increased virulence (hypervirulence),,,,,increased,increased,,increased,increased,no,Congo red (CR); H2O2,congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Overexpression of the bcxyr1 gene led to impaired spore germination and increase fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21199,PHI:123724,UniProt,A0A384JYH5,GenBank,ATZ55630,,,B05.10,BcXyr1,chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,reduced virulence,,,,,reduced,reduced,,reduced,reduced,no,Congo red (CR); H2O2,congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Deletion of the bcxyr1 gene led to impaired spore germination and reduced fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21200,PHI:123724,UniProt,A0A384JYH5,GenBank,ATZ55630,,,B05.10,BcXyr1,chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,increased virulence (hypervirulence),,,,,increased,increased,,increased,increased,no,Congo red (CR); H2O2,congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Overexpression of the bcxyr1 gene led to impaired spore germination and increase fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21201,PHI:123724,UniProt,A0A384JYH5,GenBank,ATZ55630,,,B05.10,BcXyr1,chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,reduced virulence,,,,,,,,,,no,Congo red (CR); H2O2,congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Deletion of the bcxyr1 gene led to impaired spore germination and reduced fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21202,PHI:123724,UniProt,A0A384JYH5,GenBank,ATZ55630,,,B05.10,BcXyr1,chromosome BCIN12,,,,,,40559,Botrytis cinerea,332648,B05.10,,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,increased virulence (hypervirulence),,,,,,,,,,no,Congo red (CR); H2O2,congo red: CHEBI:34653; H2O2: CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Overexpression of the bcxyr1 gene led to impaired spore germination and increase fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21203,PHI:123725,,no data found,,,,,,Bcexl1,,,,,,,40559,Botrytis cinerea,332648,B05.10,,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Deletion of the bcexl1 gene led to impaired spore germination and reduced fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21204,PHI:123724,UniProt,A0A384JYH5,GenBank,ATZ55630,,,B05.10,BcXyr1,chromosome BCIN12,,,,,PHI:123725,40559,Botrytis cinerea,332648,B05.10,,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Deletion of the bcxyr1 gene led to impaired spore germination and reduced fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21205,PHI:123725,,no data found,,,,,,Bcexl1,,,,,,PHI:123724,40559,Botrytis cinerea,332648,B05.10,,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,transcription factor,,,carbohydrate and amino acid metabolism,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36468854,PubMed,10.1128/msystems.01042-22,mSystems. 2022 Dec 20;7(6):e0104222,liangm2008@outlook.com,Deletion of the bcexl1 gene led to impaired spore germination and reduced fungal virulence and reactive oxygen species (ROS) production.,L Ma 2022,2022,2 genes,Ma et al 2023 msystems.01042-22,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21206,PHI:123726,UniProt,A1TJD3,GenBank,ABM31071,,,AAC00-1,hrpE (Aave_0464),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 3; cv. Ruixin,,,seedling; leaf,type III secretion protein,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,36012409,PubMed,10.3390/ijms23169144,Int J Mol Sci. 2022 Aug 15;23(16):9144,yangyuwen@caas.cn,Deletion of hrpE in A. citrulli results in the loss of pathogenicity on hosts and the hypersensitive response on non-hosts.,W Ji 2022,2022,1 gene,Ji-2022-Essential Acidovorax citrulli Virulenc,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21207,PHI:123726,UniProt,A1TJD3,GenBank,ABM31071,,,AAC00-1,hrpE (Aave_0464),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,type III secretion protein,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,36012409,PubMed,10.3390/ijms23169144,Int J Mol Sci. 2022 Aug 15;23(16):9144,yangyuwen@caas.cn,Deletion of hrpE in A. citrulli results in the loss of pathogenicity on hosts and the hypersensitive response on non-hosts.,W Ji 2022,2022,1 gene,Ji-2022-Essential Acidovorax citrulli Virulenc,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21208,PHI:123726,UniProt,A1TJD3,GenBank,ABM31071,,,AAC00-1,hrpE (Aave_0464),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,type III secretion protein,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,36012409,PubMed,10.3390/ijms23169144,Int J Mol Sci. 2022 Aug 15;23(16):9144,yangyuwen@caas.cn,Deletion of hrpE in A. citrulli results in the loss of pathogenicity on hosts and the hypersensitive response on non-hosts.,W Ji 2022,2022,1 gene,Ji-2022-Essential Acidovorax citrulli Virulenc,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21209,PHI:123727,UniProt,A1TM68,GenBank,ABM32056,,,AAC00-1,Hcp (Aave_1465),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),,,,seedling; leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36077040,PubMed,10.3390/ijms23179632,Int J Mol Sci. 2022 Aug 25;23(17):9632,yangyuwen@126.com,"Deletion of hcp reduced the competition and survival ability of Aac5 and affected growth ability in different culture media, and the decline stage of Δhcp was delayed in KB medium.",N Fei 2022,2022,2 genes,Fei-2022-Hcp of the Type VI Secretion System (,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21210,PHI:123728,UniProt,A1TM76,,,,,,tssm,,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),,,,seedling; leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36077040,PubMed,10.3390/ijms23179632,Int J Mol Sci. 2022 Aug 25;23(17):9632,yangyuwen@126.com,Deletion of tssm reduced the competition and survival ability of Aac5 and affected growth ability in different culture media.,N Fei 2022,2022,2 genes,Fei-2022-Hcp of the Type VI Secretion System (,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21211,PHI:123727,UniProt,A1TM68,GenBank,ABM32056,,,AAC00-1,Hcp (Aave_1465),,,,,,PHI:123728,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),,,,seedling; leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36077040,PubMed,10.3390/ijms23179632,Int J Mol Sci. 2022 Aug 25;23(17):9632,yangyuwen@126.com,Deletion of hcp reduced the competition and survival ability of Aac5 and affected growth ability in different culture media.,N Fei 2022,2022,2 genes,Fei-2022-Hcp of the Type VI Secretion System (,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21212,PHI:123728,UniProt,A1TM76,,,,,,tssm,,,,,,PHI:123727,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),,,,seedling; leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36077040,PubMed,10.3390/ijms23179632,Int J Mol Sci. 2022 Aug 25;23(17):9632,yangyuwen@126.com,Deletion of tssm reduced the competition and survival ability of Aac5 and affected growth ability in different culture media.,N Fei 2022,2022,2 genes,Fei-2022-Hcp of the Type VI Secretion System (,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21213,PHI:123729,,no data found,GenBank,NZ_CP023687,,,KACC17005,AC-17-G1,,,,,,,80869,Paracidovorax citrulli,,KACC17005,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),,,,seed,cupin protein,,,,loss of pathogenicity,,,,,,,,wild type,,no,sodium dodecyl sulphate (SDS); kanamycin; ampicillin; D-mannose 6-phosphate,sodium dodecyl sulphate (SDS): CHEBI:8984; kanamycin: CHEBI:6104; ampicillin: CHEBI:28971; D-mannose 6-phosphate: CHEBI:17369,,,,,gene deletion: full; gene complementation,,,NN,34897248,PubMed,10.5423/PPJ.OA.08.2021.0134,Plant Pathol J. 2021 Dec;37(6):555-565,choitj@pknu.ac.kr,"Watermelon seeds coated with the mutant AC- 17-G1 showed 90% germination with no BFB symptoms where the mutant complemented with the wild-type cupin protein gene led to virulence as severe as in wild type A. citrulli, with less than 10% germination and severe BFB symptoms.",A R-Midani 2022,2022,1 gene,Rahimi-Midani-2021-Identification of a Cupin P,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21214,PHI:123730,UniProt,A1TJQ4,GenBank,ABM31192,,,AAC00-1,AopP (Aave_0588),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Ruixin,,,leaf,effector protein,,,PTI pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,33329640,PubMed,10.3389/fpls.2020.579218,Front Plant Sci. 2020 Nov 20;11:579218,zhaotgcg@163.com,ΔAopP strains exhibited reduced symptom development compared with those inoculated with the WT strain.,X Zhang 2022,2022,1 gene,Zhang-2020-Acidovorax citrulli Type III Effect,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21215,PHI:123731,UniProt,A1TJV4,GenBank,ABM31242,,,AAC00-1,yggS (Aave_0638),,,,,,,80869,Paracidovorax citrulli,,XjL12,bacterial fruit blotch,eudicots,3656,Cucumis melo (related: muskmelon),cv. Huanghou,,,seedling; seed,pyridoxal phosphate-dependent enzyme,,,,reduced virulence,,,,,mild necrotic lesions,,,wild type,,no,pyridoxal; H2O2; kanamycin; ampicillin; rifampicin; chloramphenicol; gentamicin,pyridoxal: CHEBI:16709; H2O2: CHEBI:16240; kanamycin: CHEBI:6104; ampicillin: CHEBI:28971; rifampicin: CHEBI:28077; chloramphenicol: CHEBI:17698; gentamicin: CHEBI:17833,,,,,gene deletion: full; gene complementation,,,NN,35087487,PubMed,10.3389/fmicb.2021.783862,Front Microbiol. 2022 Jan 11;12:783862,tianyanli@njau.edu.cn,"The disease indices (DI) caused by XjL12, Δyggs and CyggS were 47.87, 5.15, and 40.78, respectively. The DI of ΔyggS was significantly lower than the wild-type and complemented strains.",Y Wang 2022,2022,1 gene,Wang-2021-yggS Encoding Pyridoxal 5'-Phosphate,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21216,PHI:123732,UniProt,A1TJR0,GenBank,ABM31198,,,AAC00-1,oxyR (Aave_0594),,,,pilA(Aave_4679); fliC(Aave_4400),UniProt: A1TW76; GenBank: ABM35214; UniProt: A1TVF2; GenBank: ABM34940,,80869,Paracidovorax citrulli,397945,XjL12,bacterial fruit blotch,eudicots,3656,Cucumis melo (related: muskmelon),cv. Huanghou,,,seedling; seed,transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36204623,PubMed,10.3389/fmicb.2022.977281,Front Microbiol. 2022 Sep 20;13:977281,tianyanli@njau.edu.cn,"oxyR mutant results in reduced swimming motility, twitching motility, biofilm formation, virulence, and bacterial growth in planta by significantly affecting flagellin and type IV pili-related gene (fliC and pilA) expression.",J Wang 2022,2022,1 gene,Wang-2022-OxyR contributes to virulence of Aci,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21217,PHI:123733,UniProt,Q4UQI1,GenBank,AAY50692,,,8004,fabA (XC_3651),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase,,,FabA-FabB pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,sodium ampicillin; kanamycin sulfate; gentamycin; rifampicin,sodium ampicillin: CHEBI:34535; kanamycin sulfate: CHEBI:6109; gentamycin: CHEBI:17833; rifampicin: CHEBI:28077,,,,,gene deletion: full; gene complementation,,,NN,36515967,PubMed,10.1094/MPMI-09-22-0182-R,Mol Plant Microbe Interact. 2023 Jan 19;MPMI09220182R,wanghh36@scau.edu.cn,ΔfabA strain produced large quantity of UFAs and result indicated that the FabA-FabB pathway is not essential for growth or UFA synthesis in X. campestris pv. Campestris.,Y-H Yu 2022,2022,2 genes,Yu et al 2023 mpmi-09-22-0182-r,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21218,PHI:123734,UniProt,A0A0H2XCV9,GenBank,AAY50693,,,8004,fabB (XC_3652),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,beta-ketoacyl-[ACP] synthase I,,,FabA-FabB pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,sodium ampicillin; kanamycin sulfate; gentamycin; rifampicin,sodium ampicillin: CHEBI:34535; kanamycin sulfate: CHEBI:6109; gentamycin: CHEBI:17833; rifampicin: CHEBI:28077,,,,,gene deletion: full; gene complementation,,,NN,36515967,PubMed,10.1094/MPMI-09-22-0182-R,Mol Plant Microbe Interact. 2023 Jan 19;MPMI09220182R,wanghh36@scau.edu.cn,ΔfabB strain produced large quantity of UFAs and result indicated that the FabA-FabB pathway is not essential for growth or UFA synthesis in X. campestris pv. Campestris.,Y-H Yu 2022,2022,2 genes,Yu et al 2023 mpmi-09-22-0182-r,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21219,PHI:123728,UniProt,Q4UQI1,GenBank,AAY50692,,,8004,fabA (XC_3651),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase,,,FabA-FabB pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,sodium ampicillin; kanamycin sulfate; gentamycin; rifampicin,sodium ampicillin: CHEBI:34535; kanamycin sulfate: CHEBI:6109; gentamycin: CHEBI:17833; rifampicin: CHEBI:28077,,,,,gene deletion: full; gene complementation,,,NN,36515967,PubMed,10.1094/MPMI-09-22-0182-R,Mol Plant Microbe Interact. 2023 Jan 19;MPMI09220182R,wanghh36@scau.edu.cn,ΔfabA strain produced large quantity of UFAs and result indicated that the FabA-FabB pathway is not essential for growth or UFA synthesis in X. campestris pv. Campestris.,Y-H Yu 2022,2022,2 genes,Yu et al 2023 mpmi-09-22-0182-r,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21220,PHI:123729,UniProt,A0A0H2XCV9,GenBank,AAY50693,,,8004,fabB (XC_3652),,,,,,,339,Xanthomonas campestris,314565,pv. campestris strain 8004,black rot,eudicots,3712,Brassica oleracea (no common name found),cv. Jingfeng 1,,,leaf,beta-ketoacyl-[ACP] synthase I,,,FabA-FabB pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,sodium ampicillin; kanamycin sulfate; gentamycin; rifampicin,sodium ampicillin: CHEBI:34535; kanamycin sulfate: CHEBI:6109; gentamycin: CHEBI:17833; rifampicin: CHEBI:28077,,,,,gene deletion: full; gene complementation,,,NN,36515967,PubMed,10.1094/MPMI-09-22-0182-R,Mol Plant Microbe Interact. 2023 Jan 19;MPMI09220182R,wanghh36@scau.edu.cn,ΔfabB strain produced large quantity of UFAs and result indicated that the FabA-FabB pathway is not essential for growth or UFA synthesis in X. campestris pv. Campestris.,Y-H Yu 2022,2022,2 genes,Yu et al 2023 mpmi-09-22-0182-r,BATCH_118A,2023-01-01,MC,,,,,,,,,,,,,
,,Record 21221,PHI:123735,UniProt,A1TME9,GenBank,ABM32137,,,AAC00-1,Aave_1548,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,"Transient expression of T3S effectors from A. citrulli in N. benthamiana leaves revealed that effector, Aave_1548 trigger water-soaking-like cell death in N. benthamiana.",S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21222,PHI:123735,UniProt,A1TME9,GenBank,ABM32137,,,AAC00-1,Aave_1548,,,,,,,80869,Paracidovorax citrulli,,M6,bacterial fruit blotch,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,"Transient expression of T3S effectors from A. citrulli in N. benthamiana leaves revealed that effector, Aave_1548 trigger water-soaking-like cell death in N. benthamiana.",S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21223,PHI:123736,UniProt,A1TP56,GenBank,ABM32744,,,AAC00-1,Aave_2166,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,"Transient expression of T3S effectors from A. citrulli in N. benthamiana leaves revealed that effector, Aave_2166 trigger water-soaking-like cell death in N. benthamiana.",S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21224,PHI:123737,UniProt,A1TQP0,GenBank,ABM33278,,,AAC00-1,Aave_2708,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,"Transient expression of T3S effectors from A. citrulli in N. benthamiana leaves revealed that effector, Aave_2708 trigger water-soaking-like cell death in N. benthamiana.",S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21225,PHI:123735,UniProt,A1TME9,GenBank,ABM32137,,,AAC00-1,Aave_1548,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,Aave_1548 knockout mutants of AAC00-1 displayed virulence on Nicotiana tabacum.,S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21226,PHI:123735,UniProt,A1TME9,GenBank,ABM32137,,,AAC00-1,Aave_1548,,,,,,,80869,Paracidovorax citrulli,,M6,bacterial fruit blotch,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,Aave_1548 knockout mutants of M6 displayed virulence on Nicotiana tabacum.,S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21227,PHI:123736,UniProt,A1TP56,GenBank,ABM32744,,,AAC00-1,Aave_2166,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,Aave_2166 knockout mutants of M6 and AAC00-1 displayed virulence on Nicotiana tabacum.,S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21228,PHI:123735,UniProt,A1TME9,GenBank,ABM32137,,,AAC00-1,Aave_1548,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3656,Cucumis melo (related: muskmelon),cv. Athena; cv. Ofir,,,seed,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,Aave_1548 knockout mutants of AAC00-1 displayed reduced virulence on melon (Cucumis melo L).,S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21229,PHI:123735,UniProt,A1TME9,GenBank,ABM32137,,,AAC00-1,Aave_1548,,,,,,,80869,Paracidovorax citrulli,,M6,bacterial fruit blotch,eudicots,3656,Cucumis melo (related: muskmelon),cv. Athena; cv. Ofir,,,seed,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,Aave_1548 knockout mutants of M6 displayed reduced virulence on melon (Cucumis melo L).,S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21230,PHI:123736,UniProt,A1TP56,GenBank,ABM32744,,,AAC00-1,Aave_2166,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3656,Cucumis melo (related: muskmelon),cv. Athena; cv. Ofir,,,seed,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,Aave_2166 knockout mutants of AAC00-1 displayed reduced virulence on melon (Cucumis melo L).,S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21231,PHI:123735,UniProt,A1TME9,GenBank,ABM32137,,,AAC00-1,Aave_1548,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Sugar Baby,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,Aave_1548 knockout mutants of AAC00-1 displayed reduced virulence on watermelon.,S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21232,PHI:123735,UniProt,A1TME9,GenBank,ABM32137,,,AAC00-1,Aave_1548,,,,,,,80869,Paracidovorax citrulli,,M6,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Sugar Baby,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,Aave_1548 knockout mutants of M6 displayed reduced virulence on watermelon.,S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21233,PHI:123736,UniProt,A1TP56,GenBank,ABM32744,,,AAC00-1,Aave_2166,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Sugar Baby,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression; gene deletion: full; gene complementation,,,NN,30938096,PubMed,10.1111/mpp.12792,Mol Plant Pathol. 2019 Jun;20(6):800-814,bzhao07@vt.edu,Aave_2166 knockout mutants of AAC00-1 displayed reduced virulence on watermelon.,S M Traore 2022,2022,3 genes,Traore-2019-Nicotiana species as surrogate hos,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21234,PHI:123738,UniProt,A0A6G6JPN6,GenBank,QIE96990,,,ZJ-FGZX1,pepM,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA03-3; subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,phosphoenolpyruvate phosphomutase,,,biosynthetic pathway,reduced virulence,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,The pepM deletion mutant PNA03-3ΔpepM and PNA14-12ΔpepM did not show the necrosis phenotype and also had significantly lower population levels than the wildtype strain PNA03-3 and PNA14-12 WT on red onion scale and onion leaf tissues.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21235,PHI:123739,UniProt,Q9FCZ1,GenBank,AAG01463,,,SS104,hrcC,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA03-3; subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,type 3 secretion system secretin,,,biosynthetic pathway,unaffected pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,The hrcC deletion mutant did not result in phenotypic changes to population levels or onion disease symptoms in deletion mutant (PNA03- 3ΔhrcC) and (PNA14-12ΔhrcC) compared to the wildtype strain PNA03-3 and PNA14-12.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21236,PHI:123738,UniProt,A0A6G6JPN6,GenBank,QIE96990,,,ZJ-FGZX1,pepM,,,,,,,574096,Pantoea allii,,LMG 24248,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,phosphoenolpyruvate phosphomutase,,,biosynthetic pathway,reduced virulence,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,The deletion mutant Pal LMG24248 ΔpepM had significantly lower population levels than the LMG24248 wildtype in onion scale and leaf tissues (P < 0.0001) and also did not display symptoms on red-onion scales and on onion leaves.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21237,PHI:123740,,no data found,,,,,,halA,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,halophos,,,halophos biosynthetic pathway,unaffected pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,The strains Psi PNA14-12WT and ΔhalA showed distinct pink halo phenotypes on the red onion scales and caused necrosis on onion leaf.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21238,PHI:123741,,no data found,,,,,,halJ,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,halophos,,,halophos biosynthetic pathway,unaffected pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,The strains Psi PNA14-12WT and ΔhalJ showed distinct pink halo phenotypes on the red onion scales and caused necrosis on onion leaf.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21239,PHI:123742,,no data found,,,,,,halI,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,halophos,,,halophos biosynthetic pathway,unaffected pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,The strains Psi PNA14-12WT and ΔhalI showed distinct pink halo phenotypes on the red onion scales and caused necrosis on onion leaf.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21240,PHI:123743,,no data found,,,,,,halK,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,halophos,,,halophos biosynthetic pathway,unaffected pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,The strains Psi PNA14-12WT and ΔhalK showed distinct pink halo phenotypes on the red onion scales and caused necrosis on onion leaf.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21241,PHI:123744,,no data found,,,,,,halB,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,halophos,,,halophos biosynthetic pathway,loss of pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,ΔhalB did not display any symptoms and lesions on the red onion scales and on onion leaves.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21242,PHI:123745,,no data found,,,,,,halC,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,halophos,,,halophos biosynthetic pathway,loss of pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,ΔhalC did not display any symptoms and lesions on the red onion scales and on onion leaves.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21243,PHI:123746,,no data found,,,,,,halD,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,halophos,,,halophos biosynthetic pathway,loss of pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,ΔhalD did not display any symptoms and lesions on the red onion scales and on onion leaves.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21244,PHI:123747,,no data found,,,,,,halF,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,halophos,,,halophos biosynthetic pathway,loss of pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,ΔhalF did not display any symptoms and lesions on the red onion scales and on onion leaves.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21245,PHI:123748,,no data found,,,,,,halG,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,halophos,,,halophos biosynthetic pathway,loss of pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,ΔhalG did not display any symptoms and lesions on the red onion scales and on onion leaves.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21246,PHI:123749,,no data found,,,,,,halH,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Red Barret; cv. Century,,,leaf; bulb,halophos,,,halophos biosynthetic pathway,reduced virulence,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation; functional test in host: transient expression,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,The ΔhalH deletion mutant showed no symptoms on the red onion scales but showed reduced foliar necrosis and mean lesion length was significantly lower than wild type strain PNA14-12.,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21247,PHI:123744,,no data found,,,,,,halB,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA15-2,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Century,,,leaf,halophos,,,halophos biosynthetic pathway,increased virulence (hypervirulence),,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,functional test in host: transient expression,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,"On onion leaves, the wildtype Psi PNA15-2 did not cause foliar necrosis, while the transformant PNA15-2 pBS46::halB induced limited necrotic lesions.",M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21248,PHI:123745,,no data found,,,,,,halC,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA15-2,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Century,,,leaf,halophos,,,halophos biosynthetic pathway,increased virulence (hypervirulence),,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,functional test in host: transient expression,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,"On onion leaves, the wildtype Psi PNA15-2 did not cause foliar necrosis, while the transformant PNA15-2 pBS46::halC induced limited necrotic lesions.",M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21249,PHI:123746,,no data found,,,,,,halD,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA15-2,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Century,,,leaf,halophos,,,halophos biosynthetic pathway,increased virulence (hypervirulence),,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,functional test in host: transient expression,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,"On onion leaves, the wildtype Psi PNA15-2 did not cause foliar necrosis, while the transformant PNA15-2 pBS46::halD induced limited necrotic lesions.",M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21250,PHI:123747,,no data found,,,,,,halF,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA15-2,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Century,,,leaf,halophos,,,halophos biosynthetic pathway,increased virulence (hypervirulence),,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,functional test in host: transient expression,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,"On onion leaves, the wildtype Psi PNA15-2 did not cause foliar necrosis, while the transformant PNA15-2 pBS46::halF induced limited necrotic lesions.",M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21251,PHI:123748,,no data found,,,,,,halG,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA15-2,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Century,,,leaf,halophos,,,halophos biosynthetic pathway,increased virulence (hypervirulence),,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,functional test in host: transient expression,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,"On onion leaves, the wildtype Psi PNA15-2 did not cause foliar necrosis, while the transformant PNA15-2 pBS46::halG induced limited necrotic lesions.",M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21252,PHI:123738,UniProt,A0A6G6JPN6,GenBank,QIE96990,,,ZJ-FGZX1,pepM/halE,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA15-2,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Century,,,leaf,halophos,,,halophos biosynthetic pathway,increased virulence (hypervirulence),,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,functional test in host: transient expression,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,"On onion leaves, the wildtype Psi PNA15-2 did not cause foliar necrosis, while the transformant PNA15-2 pBS46::halE induced limited necrotic lesions.",M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21253,PHI:123749,,no data found,,,,,,halH,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA15-2,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Century,,,leaf,halophos,,,halophos biosynthetic pathway,increased virulence (hypervirulence),,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,"On onion leaves, the wildtype Psi PNA15-2 did not cause foliar necrosis, while the transformant PNA15-2 pBS46::halH induced limited necrotic lesions.",M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21254,PHI:123738,UniProt,A0A6G6JPN6,GenBank,QIE96990,,,ZJ-FGZX1,pepM,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA03-3; subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Century,,,leaf,phosphoenolpyruvate phosphomutase,,,biosynthetic pathway,unaffected pathogenicity,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,The pepM deletion mutant (PNA03-3ΔpepM) and (PNA14-12ΔpepM) reached significantly same population levels as the wild-type strain (PNA03- 3WT) and (PNA14-12WT).,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21255,PHI:123739,UniProt,Q9FCZ1,GenBank,AAG01463,,,SS104,hrcC,,,,,,,66269,Pantoea stewartii,66270,subsp. indologenes strain PNA03-3; subsp. indologenes strain PNA14-12,center rot (onion),monocots,4679,Allium cepa (related: onion),cv. Century,,,leaf,type 3 secretion system secretin,,,biosynthetic pathway,reduced virulence,,,,,,,,,,no,kanamycin; rifampicin; gentamicin; trimethoprim,kanamycin: CHEBI:6104; rifampicin: CHEBI:28077; gentamicin: CHEBI:17833; trimethoprim: CHEBI:45924,,,,,gene deletion: full; gene complementation,,,NN,36534063,PubMed,10.1094/MPMI-08-22-0165-R,Mol Plant Microbe Interact. 2022 Dec 19,bhabesh@uga.edu,The hrcC deletion mutant (PNA03-3ΔhrcC) and (PNA14-12ΔhrcC) reached significantly lower population levels than the wild-type strain (PNA03- 3WT) and (PNA14-12WT).,M Zhao 2022,2022,12 genes,Zhao et al 2023 mpmi-08-22-0165-r,BATCH_118B,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21256,PHI:123750,UniProt,A0A1Z1NKL0,GenBank,ARW81230,,,O23A,Hcp,,,,,,,645,Aeromonas salmonicida,,SRW-OG1,furunculosis,bony fishes,94232,Epinephelus coioides (related: orange-spotted grouper),,,,spleen,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,36557560,PubMed,10.3390/microorganisms10122307,Microorganisms. 2022 Nov 22;10(12):2307. doi: 10.3390/microorganisms10122307,yanqp@jmu.edu.cn,Infection with the hcp-RNAi strain resulted in significantly delayed death and a lower mortality rate in E. coioides compared with the wild-type strain infection group.,H Cai 2022,2022,1 gene,Cai-2022-Effect of the Type VI Secretion Syste,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21257,PHI:123751,UniProt,A0A0F6B881,GenBank,ACY90729,,,14028S,yhjC,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen; liver,putative transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,ampicillin,ampicillin: CHEBI:28971,,,,,gene deletion: full; gene complementation,,,NN,36674819,PubMed,10.3390/ijms24021302,Int J Mol Sci. 2023 Jan 9;24(2):1302. doi: 10.3390/ijms24021302,lihuiying0711@163.com,"The deletion of yhjC reduced the replication ability of S. Typhimurium in macrophages and decreased the colonization of S. Typhimurium in mouse, while increasing the survival rate of the infected mice, suggesting that YhjC protein promotes systemic infection by S. Typhimurium.",W Li 2023,2023,1 gene,Li-2023-The LysR-Type Transcription Regulator,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21258,PHI:123752,UniProt,A0Q7F2,GenBank,ABK90167,,,U112,mltA (FTN_1286),,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,moths,7091,Bombyx mori (related: domestic silkworm),BmN4 cell line,,,larva,murein transglycosylase A,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,33553001,PubMed,10.3389/fcimb.2020.581864,Front Cell Infect Microbiol. 2021 Jan 22;10:581864. doi: 10.3389/fcimb.2020.581864. eCollection 2020,watarai@yamaguchi-u.ac.jp,Silkworms infection with an mltA deletion mutant (ΔmltA) resulted in a reduction in the number of bacteria and prolonged survival.,T Nakamura 2021,2021,1 gene,Nakamura-2020-Identification of Membrane-Bound,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21259,PHI:123752,UniProt,A0Q7F2,GenBank,ABK90167,,,U112,mltA (FTN_1286),,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,serum,murein transglycosylase A,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,33553001,PubMed,10.3389/fcimb.2020.581864,Front Cell Infect Microbiol. 2021 Jan 22;10:581864. doi: 10.3389/fcimb.2020.581864. eCollection 2020,watarai@yamaguchi-u.ac.jp,Infection with an mltA deletion mutant (ΔmltA) resulted in a reduction in the number of bacteria and prolonged survival.,T Nakamura 2021,2021,1 gene,Nakamura-2020-Identification of Membrane-Bound,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21260,PHI:123753,UniProt,G4MND6,GenBank,EHA57050,,,70-15,Nap1,chromosome 1,,,MoNBP2 (MGG_03705); MoCLB3 (MGG_07065); MoCLB1 (MGG_03595); MoCDC28 (MGG_01362); MoGIN4 (MGG_02810); MoATS (MGG_05277); MoCYC1 (MGG_05646),UniProt: G4N6I7; GenBank: EHA49857; UniProt: G4MSL8; GenBank: EHA55439; UniProt: G4N7D5; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,nucleosome assemble protein,,,cell wall integrity pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced; defective,,no,H202; calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); NaCl; sorbitol; KCl,H2O2: CHEBI:16240; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; sodium dodecyl sulfate (SDS): CHEBI:8984; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,36675871,PubMed,10.3390/jof9010050,J Fungi (Basel). 2022 Dec 28;9(1):50. doi: 10.3390/jof9010050,zhangsl80h@ahau.edu.cn,"Deletion of MoNAP1 resulted in reduced growth and conidiation, decreased appressorium formation rate, and impaired virulence.",S Zhang 2022,2022,1 gene,"Zhang-2022-MoNap1, a Nucleosome Assemble Prote",BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21261,PHI:123753,UniProt,G4MND6,GenBank,EHA57050,,,70-15,Nap1,chromosome 1,,,MoNBP2 (MGG_03705); MoCLB3 (MGG_07065); MoCLB1 (MGG_03595); MoCDC28 (MGG_01362); MoGIN4 (MGG_02810); MoATS (MGG_05277); MoCYC1 (MGG_05646),UniProt: G4N6I7; GenBank: EHA49857; UniProt: G4MSL8; GenBank: EHA55439; UniProt: G4N7D5; Gen,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,nucleosome assemble protein,,,cell wall integrity pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced; defective,,no,H202; calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); NaCl; sorbitol; KCl,H2O2: CHEBI:16240; calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; sodium dodecyl sulfate (SDS): CHEBI:8984; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,36675871,PubMed,10.3390/jof9010050,J Fungi (Basel). 2022 Dec 28;9(1):50. doi: 10.3390/jof9010050,zhangsl80h@ahau.edu.cn,"Deletion of MoNAP1 resulted in reduced growth and conidiation, decreased appressorium formation rate, and impaired virulence.",S Zhang 2022,2022,1 gene,"Zhang-2022-MoNap1, a Nucleosome Assemble Prote",BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21262,PHI:123754,UniProt,A0A177DXD7,GenBank,OAG24327,,,SRC1lrK2f,CaMK1,unknown,,,,,,5599,Alternaria alternata,,JT-03,brown spot,eudicots,23211,Pyrus communis (related: Pear),cv. Zaosu,,,fruit,calcium/calmodulin-dependent protein kinase type I,,,ca2+ signaling pathway,reduced virulence,,,,,smaller lesions,increased,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,NN,36674895,PubMed,10.3390/ijms24021381,Int J Mol Sci. 2023 Jan 10;24(2):1381. doi: 10.3390/ijms24021381,lyc@gsau.edu.cn,"Deletion of AaCaMK1 gene significantly reduced the A. alternata conidial germination, appressorium formation and infection hyphae formation and significantly reduced the A. alternata pathogenicity.",Q Jiang 2023,2023,3 genes,Jiang-2023-AaCaMKs Positively Regulate Develop,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21263,PHI:123755,UniProt,A0A177D3T1,GenBank,OAG14345,,,SRC1lrK2f,CaMK2,unknown,,,,,,5599,Alternaria alternata,,JT-03,brown spot,eudicots,23211,Pyrus communis (related: Pear),cv. Zaosu,,,fruit,calcium/calmodulin-dependent protein kinase type 2,,,ca2+ signaling pathway,reduced virulence,,,,,smaller lesions,reduced,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,NN,36674895,PubMed,10.3390/ijms24021381,Int J Mol Sci. 2023 Jan 10;24(2):1381. doi: 10.3390/ijms24021381,lyc@gsau.edu.cn,"Deletion of AaCaMK2 gene significantly reduced the A. alternata conidial germination, appressorium formation and infection hyphae formation and significantly reduced the A. alternata pathogenicity.",Q Jiang 2023,2023,3 genes,Jiang-2023-AaCaMKs Positively Regulate Develop,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21264,PHI:123756,,no data found,,,,,,CaMK3,,,,,,,5599,Alternaria alternata,,JT-03,brown spot,eudicots,23211,Pyrus communis (related: Pear),cv. Zaosu,,,fruit,calcium/calmodulin-dependent protein kinase type 3,,,ca2+ signaling pathway,reduced virulence,,,,,smaller lesions,increased,,wild type,reduced,no,,,,,,,gene deletion: full; gene complementation,,,NN,36674895,PubMed,10.3390/ijms24021381,Int J Mol Sci. 2023 Jan 10;24(2):1381. doi: 10.3390/ijms24021381,lyc@gsau.edu.cn,"Deletion of AaCaMK3 gene significantly reduced the A. alternata conidial germination, appressorium formation and infection hyphae formation and significantly reduced the A. alternata pathogenicity.",Q Jiang 2023,2023,3 genes,Jiang-2023-AaCaMKs Positively Regulate Develop,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21265,PHI:123757,UniProt,A0A6H3T1F2,GenBank,CAA0181226,,,KPC-SM-17a,TolQ,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Tol-Pal system protein,,,,reduced virulence,,,,,,,,,,no,ampicillin; gentamicin; streptomycin; sodium dodecyl sulphate (SDS); colistin; polymyxin B; bacitracin,ampicillin: CHEBI:28971; gentamicin: CHEBI:17833; streptomycin: CHEBI:17076; sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669,,,,,gene deletion: cluster,,,NN,36648597,PubMed,10.1007/s10123-022-00319-9,Int Microbiol. 2023 Jan 17. doi: 10.1007/s10123-022-00319-9. Online ahead of print,averhoff@bio.uni-frankfurt.de,"The Δtol-pal mutant was reduced in virulence, such as 57% and 45% of the caterpillars infected with the Δtol-pal mutant survived after 2 and 3 days, whereas only 34% and 21% of the wild type larvae survived after 2 and 3 days.",J J Hubloher 2023,2022,5 genes,Hubloher-2023-The Tol-Pal system of Acinetobac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21266,PHI:123758,UniProt,A0A0B2XH13,GenBank,KHO14509,,,1,tolR,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Tol-Pal system protein,,,,reduced virulence,,,,,,,,,,no,ampicillin; gentamicin; streptomycin; sodium dodecyl sulphate (SDS); colistin; polymyxin B; bacitracin,ampicillin: CHEBI:28971; gentamicin: CHEBI:17833; streptomycin: CHEBI:17076; sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669,,,,,gene deletion: cluster,,,NN,36648597,PubMed,10.1007/s10123-022-00319-9,Int Microbiol. 2023 Jan 17. doi: 10.1007/s10123-022-00319-9. Online ahead of print,averhoff@bio.uni-frankfurt.de,"The Δtol-pal mutant was reduced in virulence, such as 57% and 45% of the caterpillars infected with the Δtol-pal mutant survived after 2 and 3 days, whereas only 34% and 21% of the wild type larvae survived after 2 and 3 days.",J J Hubloher 2023,2022,5 genes,Hubloher-2023-The Tol-Pal system of Acinetobac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21267,PHI:123759,UniProt,V5VDL0,GenBank,AKA31882,,,AB5075-UW,tolA,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Tol-Pal system protein,,,,reduced virulence,,,,,,,,,,no,ampicillin; gentamicin; streptomycin; sodium dodecyl sulphate (SDS); colistin; polymyxin B; bacitracin,ampicillin: CHEBI:28971; gentamicin: CHEBI:17833; streptomycin: CHEBI:17076; sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669,,,,,gene deletion: cluster,,,NN,36648597,PubMed,10.1007/s10123-022-00319-9,Int Microbiol. 2023 Jan 17. doi: 10.1007/s10123-022-00319-9. Online ahead of print,averhoff@bio.uni-frankfurt.de,"The Δtol-pal mutant was reduced in virulence, such as 57% and 45% of the caterpillars infected with the Δtol-pal mutant survived after 2 and 3 days, whereas only 34% and 21% of the wild type larvae survived after 2 and 3 days.",J J Hubloher 2023,2022,5 genes,Hubloher-2023-The Tol-Pal system of Acinetobac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21268,PHI:123760,UniProt,A0A7U6DI96,GenBank,AML68054,,,XH859,tolB,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Tol-Pal system protein,,,,reduced virulence,,,,,,,,,,no,ampicillin; gentamicin; streptomycin; sodium dodecyl sulphate (SDS); colistin; polymyxin B; bacitracin,ampicillin: CHEBI:28971; gentamicin: CHEBI:17833; streptomycin: CHEBI:17076; sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669,,,,,gene deletion: cluster,,,NN,36648597,PubMed,10.1007/s10123-022-00319-9,Int Microbiol. 2023 Jan 17. doi: 10.1007/s10123-022-00319-9. Online ahead of print,averhoff@bio.uni-frankfurt.de,"The Δtol-pal mutant was reduced in virulence, such as 57% and 45% of the caterpillars infected with the Δtol-pal mutant survived after 2 and 3 days, whereas only 34% and 21% of the wild type larvae survived after 2 and 3 days.",J J Hubloher 2023,2022,5 genes,Hubloher-2023-The Tol-Pal system of Acinetobac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21269,PHI:123761,UniProt,A0A3Q8UJS1,GenBank,AZM38883,,,WPB103,pal,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,Tol-Pal system protein,,,,reduced virulence,,,,,,,,,,no,ampicillin; gentamicin; streptomycin; sodium dodecyl sulphate (SDS); colistin; polymyxin B; bacitracin,ampicillin: CHEBI:28971; gentamicin: CHEBI:17833; streptomycin: CHEBI:17076; sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669,,,,,gene deletion: cluster,,,NN,36648597,PubMed,10.1007/s10123-022-00319-9,Int Microbiol. 2023 Jan 17. doi: 10.1007/s10123-022-00319-9. Online ahead of print,averhoff@bio.uni-frankfurt.de,"The Δtol-pal mutant was reduced in virulence, such as 57% and 45% of the caterpillars infected with the Δtol-pal mutant survived after 2 and 3 days, whereas only 34% and 21% of the wild type larvae survived after 2 and 3 days.",J J Hubloher 2023,2022,5 genes,Hubloher-2023-The Tol-Pal system of Acinetobac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21270,PHI:123757,UniProt,A0A6H3T1F2,GenBank,CAA0181226,,,KPC-SM-17a,TolQ,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,Tol-Pal system protein,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; gentamicin; streptomycin; sodium dodecyl sulphate (SDS); colistin; polymyxin B; bacitracin,ampicillin: CHEBI:28971; gentamicin: CHEBI:17833; streptomycin: CHEBI:17076; sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669,,,,,gene deletion: cluster,,,NN,36648597,PubMed,10.1007/s10123-022-00319-9,Int Microbiol. 2023 Jan 17. doi: 10.1007/s10123-022-00319-9. Online ahead of print,averhoff@bio.uni-frankfurt.de,Deletion of the tol-pal system did not increase the susceptibility to human serum or LL-37.,J J Hubloher 2023,2022,5 genes,Hubloher-2023-The Tol-Pal system of Acinetobac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21271,PHI:123758,UniProt,A0A0B2XH13,GenBank,KHO14509,,,1,tolR,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,Tol-Pal system protein,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; gentamicin; streptomycin; sodium dodecyl sulphate (SDS); colistin; polymyxin B; bacitracin,ampicillin: CHEBI:28971; gentamicin: CHEBI:17833; streptomycin: CHEBI:17076; sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669,,,,,gene deletion: cluster,,,NN,36648597,PubMed,10.1007/s10123-022-00319-9,Int Microbiol. 2023 Jan 17. doi: 10.1007/s10123-022-00319-9. Online ahead of print,averhoff@bio.uni-frankfurt.de,Deletion of the tol-pal system did not increase the susceptibility to human serum or LL-37.,J J Hubloher 2023,2022,5 genes,Hubloher-2023-The Tol-Pal system of Acinetobac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21272,PHI:123759,UniProt,V5VDL0,GenBank,AKA31882,,,AB5075-UW,tolA,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,Tol-Pal system protein,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; gentamicin; streptomycin; sodium dodecyl sulphate (SDS); colistin; polymyxin B; bacitracin,ampicillin: CHEBI:28971; gentamicin: CHEBI:17833; streptomycin: CHEBI:17076; sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669,,,,,gene deletion: cluster,,,NN,36648597,PubMed,10.1007/s10123-022-00319-9,Int Microbiol. 2023 Jan 17. doi: 10.1007/s10123-022-00319-9. Online ahead of print,averhoff@bio.uni-frankfurt.de,Deletion of the tol-pal system did not increase the susceptibility to human serum or LL-37.,J J Hubloher 2023,2022,5 genes,Hubloher-2023-The Tol-Pal system of Acinetobac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21273,PHI:123760,UniProt,A0A7U6DI96,GenBank,AML68054,,,XH859,tolB,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,Tol-Pal system protein,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; gentamicin; streptomycin; sodium dodecyl sulphate (SDS); colistin; polymyxin B; bacitracin,ampicillin: CHEBI:28971; gentamicin: CHEBI:17833; streptomycin: CHEBI:17076; sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669,,,,,gene deletion: cluster,,,NN,36648597,PubMed,10.1007/s10123-022-00319-9,Int Microbiol. 2023 Jan 17. doi: 10.1007/s10123-022-00319-9. Online ahead of print,averhoff@bio.uni-frankfurt.de,Deletion of the tol-pal system did not increase the susceptibility to human serum or LL-37.,J J Hubloher 2023,2022,5 genes,Hubloher-2023-The Tol-Pal system of Acinetobac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21274,PHI:123761,UniProt,A0A3Q8UJS1,GenBank,AZM38883,,,WPB103,pal,,,,,,,470,Acinetobacter baumannii,575584,ATCC 19606,nosocomial infection,primates,9606,Homo sapiens (related: human),,,,serum,Tol-Pal system protein,,,,unaffected pathogenicity,,,,,,,,,,no,ampicillin; gentamicin; streptomycin; sodium dodecyl sulphate (SDS); colistin; polymyxin B; bacitracin,ampicillin: CHEBI:28971; gentamicin: CHEBI:17833; streptomycin: CHEBI:17076; sodium dodecyl sulphate (SDS): CHEBI:8984; colistin: CHEBI:37943; polymyxin B: CHEBI:8309; bacitracin: CHEBI:28669,,,,,gene deletion: cluster,,,NN,36648597,PubMed,10.1007/s10123-022-00319-9,Int Microbiol. 2023 Jan 17. doi: 10.1007/s10123-022-00319-9. Online ahead of print,averhoff@bio.uni-frankfurt.de,Deletion of the tol-pal system did not increase the susceptibility to human serum or LL-37.,J J Hubloher 2023,2022,5 genes,Hubloher-2023-The Tol-Pal system of Acinetobac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21275,PHI:123762,UniProt,A0A384JP31,GenBank,ATZ52346,,,B05.10,bccpdh,BCIN08,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,NAD(P)-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36712336,PubMed,10.1093/pnasnexus/pgac274,PNAS Nexus. 2022 Dec 21;1(5):pgac274. doi: 10.1093/pnasnexus/pgac274. eCollection 2022 Nov,dtakemo@agr.nagoya-u.ac.jp,"In N. benthamiana, the development of disease symptoms by Δbccpdh was significantly reduced compared with those caused by wild type B. cinerea.",T Kuroyanagi 2022,2022,1 gene,Kuroyanagi-2022-Botrytis cinerea identifies ho,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21276,PHI:123762,UniProt,A0A384JP31,GenBank,ATZ52346,,,B05.10,bccpdh,BCIN08,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,leaf; fruit,NAD(P)-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36712336,PubMed,10.1093/pnasnexus/pgac274,PNAS Nexus. 2022 Dec 21;1(5):pgac274. doi: 10.1093/pnasnexus/pgac274. eCollection 2022 Nov,dtakemo@agr.nagoya-u.ac.jp,"In C. annuum, the development of disease symptoms by Δbccpdh was significantly reduced compared with those caused by wild type B. cinerea.",T Kuroyanagi 2022,2022,1 gene,Kuroyanagi-2022-Botrytis cinerea identifies ho,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21277,PHI:123762,UniProt,A0A384JP31,GenBank,ATZ52346,,,B05.10,bccpdh,BCIN08,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4097,Nicotiana tabacum (related: common tobacco),,,,leaf,NAD(P)-binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36712336,PubMed,10.1093/pnasnexus/pgac274,PNAS Nexus. 2022 Dec 21;1(5):pgac274. doi: 10.1093/pnasnexus/pgac274. eCollection 2022 Nov,dtakemo@agr.nagoya-u.ac.jp,"In N. tabacum, the development of disease symptoms by Δbccpdh was significantly reduced compared with those caused by wild type B. cinerea.",T Kuroyanagi 2022,2022,1 gene,Kuroyanagi-2022-Botrytis cinerea identifies ho,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21278,PHI:123762,UniProt,A0A384JP31,GenBank,ATZ52346,,,B05.10,bccpdh,BCIN08,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber; leaf,NAD(P)-binding protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36712336,PubMed,10.1093/pnasnexus/pgac274,PNAS Nexus. 2022 Dec 21;1(5):pgac274. doi: 10.1093/pnasnexus/pgac274. eCollection 2022 Nov,dtakemo@agr.nagoya-u.ac.jp,"Both wild type and Δbccpdh strains caused comparable symptoms in potato, which is consistent with the finding that expression of Bccpdh is not induced during the infection in the plant.",T Kuroyanagi 2022,2022,1 gene,Kuroyanagi-2022-Botrytis cinerea identifies ho,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21279,PHI:123762,UniProt,A0A384JP31,GenBank,ATZ52346,,,B05.10,bccpdh,BCIN08,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4111,Solanum melongena (related: eggplant),,,,leaf,NAD(P)-binding protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36712336,PubMed,10.1093/pnasnexus/pgac274,PNAS Nexus. 2022 Dec 21;1(5):pgac274. doi: 10.1093/pnasnexus/pgac274. eCollection 2022 Nov,dtakemo@agr.nagoya-u.ac.jp,Both wild type and Δbccpdh strains caused comparable symptoms in eggplant which is consistent with the finding that expression of Bccpdh is not induced during the infection in the plant.,T Kuroyanagi 2022,2022,1 gene,Kuroyanagi-2022-Botrytis cinerea identifies ho,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21280,PHI:123762,UniProt,A0A384JP31,GenBank,ATZ52346,,,B05.10,bccpdh,BCIN08,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,2599121,Vitis x labruscana (no common name found),,,,leaf,NAD(P)-binding protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36712336,PubMed,10.1093/pnasnexus/pgac274,PNAS Nexus. 2022 Dec 21;1(5):pgac274. doi: 10.1093/pnasnexus/pgac274. eCollection 2022 Nov,dtakemo@agr.nagoya-u.ac.jp,"Both wild type and Δbccpdh strains caused comparable symptoms in grape, which is consistent with the finding that expression of Bccpdh is not induced during the infection in the plant.",T Kuroyanagi 2022,2022,1 gene,Kuroyanagi-2022-Botrytis cinerea identifies ho,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21281,PHI:123762,UniProt,A0A384JP31,GenBank,ATZ52346,,,B05.10,bccpdh,BCIN08,,,,,,40559,Botrytis cinerea,,,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,NAD(P)-binding protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36712336,PubMed,10.1093/pnasnexus/pgac274,PNAS Nexus. 2022 Dec 21;1(5):pgac274. doi: 10.1093/pnasnexus/pgac274. eCollection 2022 Nov,dtakemo@agr.nagoya-u.ac.jp,"Both wild type and Δbccpdh strains caused comparable symptoms in tomato, which is consistent with the finding that expression of Bccpdh is not induced during the infection in the plant.",T Kuroyanagi 2022,2022,1 gene,Kuroyanagi-2022-Botrytis cinerea identifies ho,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21282,PHI:123763,UniProt,G4N850,GenBank,EHA50951,,,70-15,Snf5 (MGG_06315),chromosome 4,"Deletion mutant was complemented with N-terminal region (412–771 aa) plus Snf5 domain, N-terminal region only, C-terminal region only, N+C terminal region or C-terminal region plus Snf5 domain",,MoSnf21 (MGG_06388); MoTaf14 (MGG_05204); MoSsr3 (MGG_01794); MoPcna1 (MGG_00518),UniProt: G4N7K9; GenBank: EHA50866; UniProt: G4N531; GenBank: EHA52942; UniProt: G4MVS9; Gen,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,transcription regulatory protein SNF5,,,galactose metabolism pathway,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS),calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,36675839,PubMed,10.3390/jof9010018,J Fungi (Basel). 2022 Dec 22;9(1):18. doi: 10.3390/jof9010018,yangj@cau.edu.cn,"The gene deletion mutants of MoSNF5 exhibited slower vegetative hyphal growth, severe defects in conidiogenesis, and impaired virulence and galactose utilization capacities. Complementation of N-terminus region to the deletion mutant exhibited the best effects on rescuing defects of the ΔMosnf5 mutants.",X W Xu 2022,2022,2 genes,"Xu-2022-MoSnf5 Regulates Fungal Virulence, Gro",BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21283,PHI:123763,UniProt,G4N850,GenBank,EHA50951,,,70-15,Snf5 (MGG_06315),chromosome 4,"Deletion mutant was complemented with N-terminal region (412–771 aa) plus Snf5 domain, N-terminal region only, C-terminal region only, N+C terminal region or C-terminal region plus Snf5 domain",,MoSnf21 (MGG_06388); MoTaf14 (MGG_05204); MoSsr3 (MGG_01794); MoPcna1 (MGG_00518),UniProt: G4N7K9; GenBank: EHA50866; UniProt: G4N531; GenBank: EHA52942; UniProt: G4MVS9; Gen,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,transcription regulatory protein SNF5,,,galactose metabolism pathway,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS),calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,36675839,PubMed,10.3390/jof9010018,J Fungi (Basel). 2022 Dec 22;9(1):18. doi: 10.3390/jof9010018,yangj@cau.edu.cn,"The gene deletion mutants of MoSNF5 exhibited slower vegetative hyphal growth, severe defects in conidiogenesis, and impaired virulence and galactose utilization capacities. Complementation of N-terminus region to the deletion mutant exhibited the best effects on rescuing defects of the ΔMosnf5 mutants.",X W Xu 2022,2022,2 genes,"Xu-2022-MoSnf5 Regulates Fungal Virulence, Gro",BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21284,PHI:123764,UniProt,G4N531,GenBank,EHA52942,,,70-15,Taf14 (MGG_05204),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,transcription initiation factor TFIID subunit,,,galactose metabolism pathway,reduced virulence,,,,,reduced lesion,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS),calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,NN,36675839,PubMed,10.3390/jof9010018,J Fungi (Basel). 2022 Dec 22;9(1):18. doi: 10.3390/jof9010018,yangj@cau.edu.cn,ΔMoTaf14 mutants showed similar phenotypes as the ΔMosnf5 mutants on fungal virulence and development.,X W Xu 2022,2022,2 genes,"Xu-2022-MoSnf5 Regulates Fungal Virulence, Gro",BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21285,PHI:123764,UniProt,G4N531,GenBank,EHA52942,,,70-15,Taf14 (MGG_05204),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,transcription initiation factor TFIID subunit,,,galactose metabolism pathway,reduced virulence,,,,,reduced lesion,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS),calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full,,,NN,36675839,PubMed,10.3390/jof9010018,J Fungi (Basel). 2022 Dec 22;9(1):18. doi: 10.3390/jof9010018,yangj@cau.edu.cn,ΔMoTaf14 mutants showed similar phenotypes as the ΔMosnf5 mutants on fungal virulence and development.,X W Xu 2022,2022,2 genes,"Xu-2022-MoSnf5 Regulates Fungal Virulence, Gro",BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21286,PHI:123765,UniProt,A0A3M7JTW8,GenBank,QRD82764,,,NRRL 3357,Ngg1,chromosome 2,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,histone 2-hydroxyisobutyryltransferase,,,,reduced virulence,,,,,,reduced,,reduced; defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36668827,PubMed,10.3390/toxins15010007,Toxins (Basel). 2022 Dec 21;15(1):7. doi: 10.3390/toxins15010007,lvyangyong@haut.edu.cn,"Afngg1 deletion inhibited mycelial growth of A. flavus, and the number of conidia and hydrophobicity were significantly decreased.",J Wang 2022,2022,1 gene,Wang-2022-Histone 2-Hydroxyisobutyryltransfera,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21287,PHI:123765,UniProt,A0A3M7JTW8,GenBank,QRD82764,,,NRRL 3357,Ngg1,chromosome 2,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,histone 2-hydroxyisobutyryltransferase,,,,reduced virulence,,,,,,reduced,,reduced; defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36668827,PubMed,10.3390/toxins15010007,Toxins (Basel). 2022 Dec 21;15(1):7. doi: 10.3390/toxins15010007,lvyangyong@haut.edu.cn,"Afngg1 deletion inhibited mycelial growth of A. flavus, and the number of conidia and hydrophobicity were significantly decreased.",J Wang 2022,2022,1 gene,Wang-2022-Histone 2-Hydroxyisobutyryltransfera,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21288,PHI:123766,UniProt,A0Q710,GenBank,ABK90025,,,U112,pilO,,,,,,,263,Francisella tularensis,401614,U112,tularemia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver; spleen,type IV pili component,,,endocytic pathway,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,35077486,PubMed,10.1371/journal.pone.0261938,PLoS One. 2022 Jan 25;17(1):e0261938. doi: 10.1371/journal.pone.0261938. eCollection 2022,marina.santic@uniri.hr,"Intradermal (i.d.) infection of BALB/c mice with all doses of the pilO mutant strain tested (102, 103, 104, 105 and 106 CFU/mouse) resulted in a 100% survival rate.",M Ozanic 2022,2022,1 gene,Ozanic-2022-The type IV pili component PilO is,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21289,PHI:123767,,no data found,,,,,,RyhB-1,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SE50336,salmonellosis,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,,small non-coding RNAs,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36677506,PubMed,10.3390/microorganisms11010214,Microorganisms. 2023 Jan 15;11(1):214. doi: 10.3390/microorganisms11010214,mengxia_1@126.com,"Deletion of ryhB-1 increased the survival of S. Enteritidis, and the effect of the ΔryhB-1 mutant was the greatest.",X Meng 2023,2023,2 genes,Meng-2023-RyhB Paralogs Downregulate the Expre,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21290,PHI:123768,,no data found,,,,,,RyhB-2,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SE50336,salmonellosis,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,,small non-coding RNAs,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36677506,PubMed,10.3390/microorganisms11010214,Microorganisms. 2023 Jan 15;11(1):214. doi: 10.3390/microorganisms11010214,mengxia_1@126.com,"Deletion of ryhB-2 increased the survival of S. Enteritidis, and the effect of the ΔryhB-2 mutant was the greater than wild type.",X Meng 2023,2023,2 genes,Meng-2023-RyhB Paralogs Downregulate the Expre,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21291,PHI:123767,,no data found,,,,,,RyhB-1,,,,,,PHI:123768,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SE50336,salmonellosis,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,,small non-coding RNAs,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36677506,PubMed,10.3390/microorganisms11010214,Microorganisms. 2023 Jan 15;11(1):214. doi: 10.3390/microorganisms11010214,mengxia_1@126.com,"RyhB-1 and RyhB-2 together, contributed to attenuating the intracellular Salmonella survival ability in HD11.",X Meng 2023,2023,2 genes,Meng-2023-RyhB Paralogs Downregulate the Expre,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21292,PHI:123768,,no data found,,,,,,RyhB-2,,,,,,PHI:123767,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain SE50336,salmonellosis,birds,9031,Gallus gallus (related: chicken),LSCC-HD11 cell line,,,,small non-coding RNAs,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36677506,PubMed,10.3390/microorganisms11010214,Microorganisms. 2023 Jan 15;11(1):214. doi: 10.3390/microorganisms11010214,mengxia_1@126.com,"RyhB-1 and RyhB-2 together, contributed to attenuating the intracellular Salmonella survival ability in HD11.",X Meng 2023,2023,2 genes,Meng-2023-RyhB Paralogs Downregulate the Expre,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21293,PHI:123769,UniProt,A0A0D2XCW5,GenBank,KNA96647,,,4287,pro1 (FOXG_01740),chromosome 5,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici strain 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,transcriptional regulatory protein,,,mitogen-activated protein kinase (MAPK) signaling pathway,unaffected pathogenicity,,,,,,reduced,,reduced,,no,glucose; α-pheromone,glucose: CHEBI:17234; α-pheromone: CHEBI:26013,,,,,gene deletion: full; gene complementation,,,NN,36547575,PubMed,10.3390/jof8121242,J Fungi (Basel). 2022 Nov 24;8(12):1242. doi: 10.3390/jof8121242,ge2dipia@uco.es,pro1Δ mutants caused similar levels of mortality on tomato plants as the wt.,R Palos-Fernández 2022,2022,1 gene,Palos-Fernández-2022-The Gal4-Type Transcripti,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21294,PHI:123770,UniProt,B8N0V6,GenBank,QMW28541,,,NRRL3357,ZKS3,chromosome 2,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),,,,seed,C2H2 transcription factor,,,AFB1 synthesis pathway,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,36548780,PubMed,10.3390/toxins14120883,Toxins (Basel). 2022 Dec 17;14(12):883. doi: 10.3390/toxins14120883,lvyangyong@haut.edu.cn,Gene deletion in A. flavus resulted in defective growth and conidia formation; ZKS3 affect A. flavus pathogenicity by inhibiting A. flavus colonization and AF production.,L Liang 2022,2022,1 gene,Liang-2022-Putative C(2)H(2) Transcription Fac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21295,PHI:123770,UniProt,B8N0V6,GenBank,QMW28541,,,NRRL3357,ZKS3,chromosome 2,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),eudicots,3818,Arachis hypogaea (related: peanut),,,,seed,C2H2 transcription factor,,,AFB1 synthesis pathway,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911,,,,,gene deletion: full; gene complementation,,,NN,36548780,PubMed,10.3390/toxins14120883,Toxins (Basel). 2022 Dec 17;14(12):883. doi: 10.3390/toxins14120883,lvyangyong@haut.edu.cn,Gene deletion in A. flavus resulted in defective growth and conidia formation; ZKS3 affect A. flavus pathogenicity by inhibiting A. flavus colonization and AF production.,L Liang 2022,2022,1 gene,Liang-2022-Putative C(2)H(2) Transcription Fac,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21296,PHI:123771,,no data found,GenBank,2847761,,,,ryhB,,,,,,,562,Escherichia coli,,APEC O2:K1:H7 strain M78,avian colibacillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,brain; spleen; lung,small non-coding RNAs,,,,reduced virulence,,,,,no lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36555174,PubMed,10.3390/ijms232415532,Int J Mol Sci. 2022 Dec 8;23(24):15532. doi: 10.3390/ijms232415532,wh@yzu.edu.cn,"Deletion of ryhB reduced the clinical symptoms of mice, such as opisthotonus, diarrhea and neurological signs.",X Meng 2022,2022,1 gene,Meng-2022-RyhB in Avian Pathogenic Escherichia,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21297,PHI:123772,UniProt,G7SDG9,GenBank,AER18659,,,D12,Lmb,,,,,,,1307,Streptococcus suis,218494,P1/7,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,blood,laminin binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36604750,PubMed,10.1186/s13567-022-01128-8,Vet Res. 2023 Jan 5;54(1):1. doi: 10.1186/s13567-022-01128-8,marcelo.gottschalk@umontreal.ca,20% of mice infected with the Δlmb mutant succumbed to disease compared to wild type.,S Payen 2023,2023,1 gene,Payen-2023-Laminin-binding protein of Streptoc,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21298,PHI:123773,,no data found,,,,,,CRISIS2,,,,,,,4784,Phytophthora capsici,,40476,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transient overexpression,,,NN,36571808,PubMed,10.1093/jxb/erac500,J Exp Bot. 2022 Dec 26:erac500. doi: 10.1093/jxb/erac500. Online ahead of print,doil@snu.ac.kr,In planta expression of CRISIS2 significantly enhanced the virulence of P. capsici.,Y E Seo 2022,2022,1 gene,Seo-2022-The Phytophthora capsici RxLR effecto,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21299,PHI:123773,,no data found,,,,,,CRISIS2,,,,,,,4784,Phytophthora capsici,,40476,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,36571808,PubMed,10.1093/jxb/erac500,J Exp Bot. 2022 Dec 26:erac500. doi: 10.1093/jxb/erac500. Online ahead of print,doil@snu.ac.kr,Host-induced gene-silencing of CRISIS2 compromised the disease symptoms and the biomass of the pathogen.,Y E Seo 2022,2022,1 gene,Seo-2022-The Phytophthora capsici RxLR effecto,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21300,PHI:123774,UniProt,B3FN69,GenBank,ABZ02174,,,AIP180.04,cdtR,,,,,,,1496,Clostridioides difficile,645463,R20291,nosocomial diarrhea,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,cecum,transcriptional regulator,,,,loss of pathogenicity,,,,,,,,,,no,metronidazole; neomycin; vancomycin,metronidazole: CHEBI:6909; neomycin: CHEBI:7507; vancomycin: CHEBI:28001,,,,,gene deletion: full,,,NN,36711955,PubMed,10.1101/2023.01.12.523823,bioRxiv. 2023 Jan 12:2023.01.12.523823. doi: 10.1101/2023.01.12.523823. Preprint,egpamer@uchicago.edu,Genetic deletion of the 69 base-pair cdtR sequence in the highly virulent ST R20291 C. difficile strain rendered it avirulent and reduced toxin gene transcription in cecal contents.,Q Dong 2023,2023,1 gene,Dong-2023-Virulence and genomic diversity amon,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21301,PHI:123775,UniProt,F6G3S6,GenBank,AEG69973,,,Po82,wecA,,,,,,,305,Ralstonia solanacearum,,QL-Rs1115,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Hezuo 903,,,seedling,glycosyl transferase gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36635489,PubMed,10.1038/s41396-023-01356-6,ISME J. 2023 Jan 12. doi: 10.1038/s41396-023-01356-6. Online ahead of print,waseem@njau.edu.cn,Mutant shows reduced virulence in planta relative to the ancestral strain and the effect was stronger with ΔwecA (32% reduction).,J Wang 2023,2023,2 genes,Wang-2023-Bacterial volatile organic compounds,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21302,PHI:123776,UniProt,A3RW16,GenBank,EAP72312,,,UW551,pilM,,,,,,,305,Ralstonia solanacearum,,QL-Rs1115,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Hezuo 903,,,seedling,protein-encoding gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36635489,PubMed,10.1038/s41396-023-01356-6,ISME J. 2023 Jan 12. doi: 10.1038/s41396-023-01356-6. Online ahead of print,waseem@njau.edu.cn,Mutant shows reduced virulence in planta relative to the ancestral strain and the effect was much stronger with ΔpilM (58% reduction).,J Wang 2023,2023,2 genes,Wang-2023-Bacterial volatile organic compounds,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21303,PHI:123777,UniProt,S7UPV8,GenBank,EPR59725,,,GT1,CPC1 (TGGT1_289620),,,,,,,5811,Toxoplasma gondii,383379,RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,cathepsin C-like protease,,,secretory pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36712013,PubMed,10.1101/2023.01.21.525043,bioRxiv. 2023 Jan 22:2023.01.21.525043. doi: 10.1101/2023.01.21.525043. Preprint,zdou@clemson.edu,The mice infected with Δcpc1 survived significantly longer than mice infected with WT or Δcpc1CPC1 parasites,L B Thornton 2023,,1 gene,Thornton-2023-A cathepsin C-like protease post,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21304,PHI:123778,,no data found,GenBank,EXL51339,,,26381,MC69,unknown,,,,,,5507,Fusarium oxysporum,,f. sp. radicis-lycopersici strain MAFF 103007,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ponderosa,,,root,,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36558767,PubMed,10.3390/pathogens11121433,Pathogens. 2022 Nov 28;11(12):1433. doi: 10.3390/pathogens11121433,shinsan@yamaguchi-u.ac.jp,"FoMC69-knockout mutant of Forl had significantly reduced root rot symptoms compared to the wild-type strain, and full pathogenicity was restored by complementation",K Sasaki 2022,2022,2 genes,Sasaki-2022-FoMC69 Gene in Fusarium oxysporum,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21305,PHI:123779,,no data found,,,,,,MC69,,,,,,,5507,Fusarium oxysporum,,f. sp. lycopersici strain CK3-1,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ponderosa,,,root; leaf; stem,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36558767,PubMed,10.3390/pathogens11121433,Pathogens. 2022 Nov 28;11(12):1433. doi: 10.3390/pathogens11121433,shinsan@yamaguchi-u.ac.jp,The ΔFoMC69 mutant of Fol caused severe disease symptoms similar to the wild-type strain at 21 dpi.,K Sasaki 2022,2022,2 genes,Sasaki-2022-FoMC69 Gene in Fusarium oxysporum,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21306,PHI:123778,,no data found,GenBank,EXL51339,,,26381,MC69,unknown,,,,,,5507,Fusarium oxysporum,,f. sp. radicis-lycopersici strain MAFF 103007,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Ponderosa,,,leaf; stem,,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36558767,PubMed,10.3390/pathogens11121433,Pathogens. 2022 Nov 28;11(12):1433. doi: 10.3390/pathogens11121433,shinsan@yamaguchi-u.ac.jp,"ΔFoMC69 mutant was inoculated into tomato plants, there were no symptoms in the leaf and stem parts as well as in the wild-type plants at 21 dpi.",K Sasaki 2022,2022,2 genes,Sasaki-2022-FoMC69 Gene in Fusarium oxysporum,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21307,PHI:123780,,no data found,,,,,,ELV1 (VDAG_JR2_Chr6g05120a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,Egh16-like virulence factor 1,,,,reduced virulence,,,,,,wild type,,wild type,,no,SDS,sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,36716333,PubMed,10.1371/journal.ppat.1011100,PLoS Pathog. 2023 Jan 30;19(1):e1011100. doi: 10.1371/journal.ppat.1011100. Online ahead of print,gbraus@gwdg.de,Deletion of ELV1 resulted in approximately 25% more plants with no or only weak symptoms compared with wild-type-infected plants.,I Maurus 2023,2023,2 genes,Maurus-2023-Verticillium dahliae Vta3 promotes,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21308,PHI:123781,,no data found,,,,,,MTF1 (VDAG_JR2_Chr2g08470a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,master transcription factor 1,,,,reduced virulence,,,,,,wild type,,wild type,,no,SDS,sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,36716333,PubMed,10.1371/journal.ppat.1011100,PLoS Pathog. 2023 Jan 30;19(1):e1011100. doi: 10.1371/journal.ppat.1011100. Online ahead of print,gbraus@gwdg.de,60% of plants treated with the MTF1 deletion strain were either healthy or displayed only a mild stunting phenotype.,I Maurus 2023,2023,2 genes,Maurus-2023-Verticillium dahliae Vta3 promotes,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21309,PHI:123782,UniProt,Q9I616,GenBank,AAG03891,,,PAO1,bioH (PA0502),,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,biotin biosynthesis protein,,,biotin synthesis pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36689471,PubMed,10.1371/journal.ppat.1011110,PLoS Pathog. 2023 Jan 23;19(1):e1011110. doi: 10.1371/journal.ppat.1011110. eCollection 2023 Jan,llan@ucas.ac.cn,Deletion of bioH reduces the virulence of P. aeruginosa in mouse lung infections.,Y Shi 2023,2023,1 gene,Shi-2023-The opportunistic pathogen Pseudomona,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21310,PHI:123783,UniProt,Q6FMQ2,GenBank,CAG61453,,,CBS 138,ada2,chromosome K,,,,,,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Deletion of Ada2 resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9) , defective growth and exhibits marginal hypervirulence in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21311,PHI:123784,UniProt,Q6FVM6,GenBank,CAG58637,,,CBS 138,ada3 (CAGL0E00693g),chromosome E,,,,,,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Deletion of Ada3 resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits marginal hypervirulence in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21312,PHI:123785,UniProt,Q6FTW5,GenBank,CAG59253,,,CBS 138,gcn5 (CAGL0F08283g),chromosome F,,,,,,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Deletion of Gcn5 resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits marginal hypervirulence in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21313,PHI:123783,UniProt,Q6FMQ2,GenBank,CAG61453,,,CBS 138,ada2,chromosome K,,,,,PHI:123784,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Double deletions of the HAT module resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits hypervirulent in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21314,PHI:123784,UniProt,Q6FVM6,GenBank,CAG58637,,,CBS 138,ada3 (CAGL0E00693g),chromosome E,,,,,PHI:123783,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Double deletions of the HAT module resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits hypervirulent in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21315,PHI:123783,UniProt,Q6FMQ2,GenBank,CAG61453,,,CBS 138,ada2,chromosome K,,,,,PHI:123785,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Double deletions of the HAT module resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits hypervirulent in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21316,PHI:123785,UniProt,Q6FTW5,GenBank,CAG59253,,,CBS 138,gcn5 (CAGL0F08283g),chromosome F,,,,,PHI:123783,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Double deletions of the HAT module resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits hypervirulent in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21317,PHI:123784,UniProt,Q6FVM6,GenBank,CAG58637,,,CBS 138,ada3 (CAGL0E00693g),chromosome E,,,,,PHI:123785,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Double deletions of the HAT module resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits hypervirulent in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21318,PHI:123785,UniProt,Q6FTW5,GenBank,CAG59253,,,CBS 138,gcn5 (CAGL0F08283g),chromosome F,,,,,PHI:123784,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Double deletions of the HAT module resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits hypervirulent in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21319,PHI:123783,UniProt,Q6FMQ2,GenBank,CAG61453,,,CBS 138,ada2,chromosome K,,,,,PHI:123784; PHI:123785,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Triple deletions of the HAT module resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits hypervirulent in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21320,PHI:123784,UniProt,Q6FVM6,GenBank,CAG58637,,,CBS 138,ada3 (CAGL0E00693g),chromosome E,,,,,PHI:123783; PHI:123785,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Triple deletions of the HAT module resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits hypervirulent in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21321,PHI:123785,UniProt,Q6FTW5,GenBank,CAG59253,,,CBS 138,gcn5 (CAGL0F08283g),chromosome F,,,,,PHI:123783; PHI:123784,5478,Candida glabrata,284593,CBS138,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,histone acetyltransferase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); Congo red (CR); sodium dodecyl sulfate (SDS); dithiothreitol; fluconazole; posaconazole; voriconazole; micafungin; caspofungin; anidulafungin; amphotericin B; menadione; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; sodium dodecyl sulfate (SDS): CHEBI:8984; dithiothreitol: CHEBI:42170; fluconazole: CHEBI:46081; amphotericin B: CHEBI:2682; posaconazole: CHEBI:64355; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520; anidulafungin: CHEBI:55346; menadione: CHEBI:28869; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36715154,PubMed,10.1093/mmy/myad004,Med Mycol. 2023 Feb 3;61(2):myad004. doi: 10.1093/mmy/myad004,ychen28@ntu.edu.tw,"Triple deletions of the HAT module resulted in a decreased level of acetylation on histone H3 lysine 9 (H3K9), defective growth and exhibits hypervirulent in a murine model of candidiasis.",C J Lin 2023,2023,3 genes,Lin-2023-The Gcn5-Ada2-Ada3 histone acetyltran,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21322,PHI:123786,UniProt,Q4WYF4,GenBank,EAL92299,,,Af293,Sec1 (3g12840),chromosome 3,promoter region of AfSec1 was deleted (AfSec1-ΔP),,,,,746128,Aspergillus fumigatus,451804,A1163,pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,putative signal peptidase,,,β-glucan synthesis,reduced virulence,,,,,,reduced,,reduced,reduced,no,voriconazole; caspofungin; amphotericin B,amphotericin B: CHEBI:2682; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180,,,,,gene deletion: full; gene complementation,,,NN,36657388,PubMed,10.1093/mmy/myad005,Med Mycol. 2022 Dec 29;61(1):myad005. doi: 10.1093/mmy/myad005,cheolwony@korea.ac.kr,The virulence decreased when the promoter region of AfSec1 was deleted in the murine infection test.,K H Kim 2022,2022,1 gene,Kim-2022-AfSec1 is a signal peptidase and remo,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21323,PHI:123787,UniProt,Q868H0,,,,,,icp,,,,,,,5691,Trypanosoma brucei,31286,subsp. rhodesiense strain IL1852,African trypanosomiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,endogenous inhibitor of cysteine peptidases,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36614101,PubMed,10.3390/ijms24010656,Int J Mol Sci. 2022 Dec 30;24(1):656. doi: 10.3390/ijms24010656,anapaula@biof.ufrj.br,Infection and the parasite loads in mice infected with WT parasites were approximately 10-fold higher than those observed in mice infected with Δicp.,T F R Costa 2022,2022,1 gene,Costa-2022-Trypanosoma brucei rhodesiense Inhi,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21324,PHI:123788,UniProt,A0Q7J3,GenBank,ABK90208,,,U112,tktA (FTN_1333),,,,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,flies,7227,Drosophila melanogaster (related: fruit fly),,,,adult,transketolase I,,,pentose phosphate pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,34339477,PubMed,10.1371/journal.ppat.1009326,PLoS Pathog. 2021 Aug 2;17(8):e1009326. doi: 10.1371/journal.ppat.1009326. eCollection 2021 Aug,chiara.guerrera@inserm.fr,100% of the flies infected with the WT strain or the ΔtalA mutant strain died within 6–7 days.,H Rytter 2021,2021,4 genes,Rytter-2021-The pentose phosphate pathway cons,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21325,PHI:123789,UniProt,A0Q756,GenBank,ABK90071,,,U112,rpiA (FTN_1185),,1185::Tn::169 (U112 strain bearing a transposon insertion between the FTN_1185 and tnfn1_pw060328p07q169 genes),,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,flies,7227,Drosophila melanogaster (related: fruit fly),,,,adult,ribose 5-phospate isomerase A,,,pentose phosphate pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,34339477,PubMed,10.1371/journal.ppat.1009326,PLoS Pathog. 2021 Aug 2;17(8):e1009326. doi: 10.1371/journal.ppat.1009326. eCollection 2021 Aug,chiara.guerrera@inserm.fr,The ΔrpiA mutant was slightly less virulent than the WT and killed 90% of the flies after 10 days.,H Rytter 2021,2021,4 genes,Rytter-2021-The pentose phosphate pathway cons,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21326,PHI:123790,UniProt,A0Q787,GenBank,ABK90102,,,U112,rpe (FTN_1221),,1221::Tn::104 (U112 strain bearing a transposon insertion between the FTN_1221 and tnfn1_pw060419p02q104 genes),,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,flies,7227,Drosophila melanogaster (related: fruit fly),,,,adult,D-ribulose-phosphate 3-epimerase,,,pentose phosphate pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,34339477,PubMed,10.1371/journal.ppat.1009326,PLoS Pathog. 2021 Aug 2;17(8):e1009326. doi: 10.1371/journal.ppat.1009326. eCollection 2021 Aug,chiara.guerrera@inserm.fr,The Δrpe mutant was slightly less virulent than the WT and killed 90% of the flies after 10 days.,H Rytter 2021,2021,4 genes,Rytter-2021-The pentose phosphate pathway cons,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21327,PHI:123791,UniProt,A0Q607,GenBank,ABK89672,,,U112,talA (FTN_0781),,0781::Tn::189 (U112 strain bearing a transposon insertion between the FTN_0781 and tnfn1_pw060323p07q189 genes),,,,,263,Francisella tularensis,401614,subsp. novicida strain U112,tularemia,flies,7227,Drosophila melanogaster (related: fruit fly),,,,adult,transaldolase,,,pentose phosphate pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,34339477,PubMed,10.1371/journal.ppat.1009326,PLoS Pathog. 2021 Aug 2;17(8):e1009326. doi: 10.1371/journal.ppat.1009326. eCollection 2021 Aug,chiara.guerrera@inserm.fr,The ΔtalA mutant was slightly less virulent than the WT and killed 90% of the flies after 10 days.,H Rytter 2021,2021,4 genes,Rytter-2021-The pentose phosphate pathway cons,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21328,PHI:123792,UniProt,G4NAS8,GenBank,EHA50520,,,70-15,Ptc5 (MGG_03154),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,protein phosphatase,,,chitin synthesis,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36675822,PubMed,10.3390/jof9010001,J Fungi (Basel). 2022 Dec 20;9(1):1. doi: 10.3390/jof9010001,wangzh@fafu.edu.cn,ΔMoptc5 shows reduced virulence compared to the wild type Guy11.,J Biregeya 2022,2022,2 genes,Biregeya-2022-Type 2C Protein Phosphatases MoP,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21329,PHI:123793,UniProt,G4NE46,GenBank,EHA49375,,,70-15,Ptc7 (MGG_00166 ),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,protein phosphatase,,,chitin synthesis,reduced virulence,,,yes,,smaller lesions,wild type,,wild type,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36675822,PubMed,10.3390/jof9010001,J Fungi (Basel). 2022 Dec 20;9(1):1. doi: 10.3390/jof9010001,wangzh@fafu.edu.cn,ΔMoptc7 shows reduced virulence compared to the wild type Guy11.,J Biregeya 2022,2022,2 genes,Biregeya-2022-Type 2C Protein Phosphatases MoP,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21330,PHI:123792,UniProt,G4NAS8,GenBank,EHA50520,,,70-15,Ptc5 (MGG_03154),chromosome 4,,,,,PHI:123793,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,protein phosphatase,,,chitin synthesis,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36675822,PubMed,10.3390/jof9010001,J Fungi (Basel). 2022 Dec 20;9(1):1. doi: 10.3390/jof9010001,wangzh@fafu.edu.cn,"Double deletion of MoPTC7 and MoPTC5 suppressed the fungal vegetative growth, altered its cell wall integrity and reduced its virulence.",J Biregeya 2022,2022,2 genes,Biregeya-2022-Type 2C Protein Phosphatases MoP,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21331,PHI:123793,UniProt,G4NE46,GenBank,EHA49375,,,70-15,Ptc7 (MGG_00166 ),chromosome 5,,,,,PHI:123792,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,protein phosphatase,,,chitin synthesis,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36675822,PubMed,10.3390/jof9010001,J Fungi (Basel). 2022 Dec 20;9(1):1. doi: 10.3390/jof9010001,wangzh@fafu.edu.cn,"Double deletion of MoPTC7 and MoPTC5 suppressed the fungal vegetative growth, altered its cell wall integrity and reduced its virulence.",J Biregeya 2022,2022,2 genes,Biregeya-2022-Type 2C Protein Phosphatases MoP,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21332,PHI:123792,UniProt,G4NAS8,GenBank,EHA50520,,,70-15,Ptc5 (MGG_03154),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,protein phosphatase,,,chitin synthesis,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36675822,PubMed,10.3390/jof9010001,J Fungi (Basel). 2022 Dec 20;9(1):1. doi: 10.3390/jof9010001,wangzh@fafu.edu.cn,ΔMoptc5 shows reduced virulence compared to the wild type Guy11.,J Biregeya 2022,2022,2 genes,Biregeya-2022-Type 2C Protein Phosphatases MoP,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21333,PHI:123793,UniProt,G4NE46,GenBank,EHA49375,,,70-15,Ptc7 (MGG_00166 ),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,protein phosphatase,,,chitin synthesis,reduced virulence,,,yes,,smaller lesions,wild type,,wild type,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36675822,PubMed,10.3390/jof9010001,J Fungi (Basel). 2022 Dec 20;9(1):1. doi: 10.3390/jof9010001,wangzh@fafu.edu.cn,ΔMoptc7 shows reduced virulence compared to the wild type Guy11.,J Biregeya 2022,2022,2 genes,Biregeya-2022-Type 2C Protein Phosphatases MoP,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21334,PHI:123792,UniProt,G4NAS8,GenBank,EHA50520,,,70-15,Ptc5 (MGG_03154),chromosome 4,,,,,PHI:123793,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,protein phosphatase,,,chitin synthesis,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36675822,PubMed,10.3390/jof9010001,J Fungi (Basel). 2022 Dec 20;9(1):1. doi: 10.3390/jof9010001,wangzh@fafu.edu.cn,"Double deletion of MoPTC7 and MoPTC5 suppressed the fungal vegetative growth, altered its cell wall integrity and reduced its virulence.",J Biregeya 2022,2022,2 genes,Biregeya-2022-Type 2C Protein Phosphatases MoP,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21335,PHI:123793,UniProt,G4NE46,GenBank,EHA49375,,,70-15,Ptc7 (MGG_00166 ),chromosome 5,,,,,PHI:123792,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,protein phosphatase,,,chitin synthesis,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,36675822,PubMed,10.3390/jof9010001,J Fungi (Basel). 2022 Dec 20;9(1):1. doi: 10.3390/jof9010001,wangzh@fafu.edu.cn,"Double deletion of MoPTC7 and MoPTC5 suppressed the fungal vegetative growth, altered its cell wall integrity and reduced its virulence.",J Biregeya 2022,2022,2 genes,Biregeya-2022-Type 2C Protein Phosphatases MoP,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21336,PHI:123794,UniProt,G4MYP1,GenBank,EHA54466,,,70-15,maf1 (MGG_15675),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,RNA polymerase (Pol) III,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36675927,PubMed,10.3390/jof9010106,J Fungi (Basel). 2023 Jan 12;9(1):106. doi: 10.3390/jof9010106,songchi@cslg.edu.cn,"ΔMomaf1 mutant exhibited reduced vegetative growth, conidiogenesis, and pathogenicity.",B Qian 2023,2023,1 gene,"Qian-2023-MoMaf1 Mediates Vegetative Growth, C",BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21337,PHI:123794,UniProt,G4MYP1,GenBank,EHA54466,,,70-15,maf1 (MGG_15675),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,RNA polymerase (Pol) III,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36675927,PubMed,10.3390/jof9010106,J Fungi (Basel). 2023 Jan 12;9(1):106. doi: 10.3390/jof9010106,songchi@cslg.edu.cn,"ΔMomaf1 mutant exhibited reduced vegetative growth, conidiogenesis, and pathogenicity.",B Qian 2023,2023,1 gene,"Qian-2023-MoMaf1 Mediates Vegetative Growth, C",BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21338,PHI:123795,,no data found,,,,,,VDH2 (VDAG_JR2_Chr4g07990a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,Infection with VDH2 single deletion strain led to wild-type-like disease outcomes.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21339,PHI:123796,,no data found,,,,,,VDH4 (VDAG_JR2_Chr3g09420a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,Single deletion of VDH4 in the JR2 wild-type background led to approximately 15–20% more plants with no or only weak symptoms.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21340,PHI:123797,,no data found,,,,,,VDH5 (VDAG_JR2_Chr1g24730a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,Single deletion of VDH5 in the JR2 wild-type background led to approximately 15–20% more plants with no or only weak symptoms.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21341,PHI:123795,,no data found,,,,,,VDH2 (VDAG_JR2_Chr4g07990a),,,,,,PHI:123797,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,Infection with VDH2/5 double deletion strains led to wild-type-like disease outcomes.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21342,PHI:123797,,no data found,,,,,,VDH5 (VDAG_JR2_Chr1g24730a),,,,,,PHI:123795,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,Infection with VDH2/5 double deletion strains led to wild-type-like disease outcomes.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21343,PHI:123796,,no data found,,,,,,VDH4 (VDAG_JR2_Chr3g09420a),,,,,,PHI:123797,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,VDH4/5 double deletion strain resulted in 25% more plants with only weak symptoms compared with wild-type-infected plants.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21344,PHI:123797,,no data found,,,,,,VDH5 (VDAG_JR2_Chr1g24730a),,,,,,PHI:123796,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,VDH4/5 double deletion strain resulted in 25% more plants with only weak symptoms compared with wild-type-infected plants.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21345,PHI:123798,,no data found,,,,,,VDH1 (VDAG_JR2_Chr2g02500a),,,,,,PHI:123796; PHI:123797,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,The additional deletion of VDH1 in the VDH4/5 deletion strain caused inoculated tomato plants to exhibit symptoms comparable to those of plants inoculated with the double deletion strain.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21346,PHI:123796,,no data found,,,,,,VDH4 (VDAG_JR2_Chr3g09420a),,,,,,PHI:123798; PHI:123797,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,The additional deletion of VDH1 in the VDH4/5 deletion strain caused inoculated tomato plants to exhibit symptoms comparable to those of plants inoculated with the double deletion strain.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21347,PHI:123797,,no data found,,,,,,VDH5 (VDAG_JR2_Chr1g24730a),,,,,,PHI:123798; PHI:123796,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,The additional deletion of VDH1 in the VDH4/5 deletion strain caused inoculated tomato plants to exhibit symptoms comparable to those of plants inoculated with the double deletion strain.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21348,PHI:123795,,no data found,,,,,,VDH2 (VDAG_JR2_Chr4g07990a),,,,,,PHI:123796; PHI:123797,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,Root inoculation with spores of the VDH2/4/5 triple deletion strain resulted in 25% more plants with only weak symptoms compared with wild-type-infected plants.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21349,PHI:123796,,no data found,,,,,,VDH4 (VDAG_JR2_Chr3g09420a),,,,,,PHI:123795; PHI:123797,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,Root inoculation with spores of the VDH2/4/5 triple deletion strain resulted in 25% more plants with only weak symptoms compared with wild-type-infected plants.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21350,PHI:123797,,no data found,,,,,,VDH5 (VDAG_JR2_Chr1g24730a),,,,,,PHI:123795; PHI:123796,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,seedling,hydrophobins,,,,reduced virulence,,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,36547586,PubMed,10.3390/jof8121252,J Fungi (Basel). 2022 Nov 27;8(12):1252. doi: 10.3390/jof8121252,rhartin@gwdg.de,Root inoculation with spores of the VDH2/4/5 triple deletion strain resulted in 25% more plants with only weak symptoms compared with wild-type-infected plants.,I Maurus 2022,2022,4 genes,Maurus-2022-Tomato Xylem Sap Hydrophobins Vdh4,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21351,PHI:123799,UniProt,A0A384JER6,GenBank,ATZ48907,,,B05.10,Mtp1 (XP_001550923.1),chromosome BCIN04,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,mitochondrial transport proteins,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced; defective,,no,Congo red (CR); NaCl; KCl; H2O2; caffeine; paraquat,Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; caffeine: CHEBI:27732; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,NN,36675846,PubMed,10.3390/jof9010025,J Fungi (Basel). 2022 Dec 23;9(1):25. doi: 10.3390/jof9010025,changjun-chen@njau.edu.cn,"The BcMtp1 deletion mutant phenotype was strikingly defective in vegetative development, conidiation, and sclerotia production; ΔBcMtp1 displayed compromised virulence on various host-plant tissues.",W Shao 2022,2022,1 gene,Shao-2022-Function of the Mitochondrial Transp,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21352,PHI:123799,UniProt,A0A384JER6,GenBank,ATZ48907,,,B05.10,Mtp1 (XP_001550923.1),chromosome BCIN04,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,leaf,mitochondrial transport proteins,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced; defective,,no,Congo red (CR); NaCl; KCl; H2O2; caffeine; paraquat,Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; caffeine: CHEBI:27732; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,NN,36675846,PubMed,10.3390/jof9010025,J Fungi (Basel). 2022 Dec 23;9(1):25. doi: 10.3390/jof9010025,changjun-chen@njau.edu.cn,"The BcMtp1 deletion mutant phenotype was strikingly defective in vegetative development, conidiation, and sclerotia production; ΔBcMtp1 displayed compromised virulence on various host-plant tissues.",W Shao 2022,2022,1 gene,Shao-2022-Function of the Mitochondrial Transp,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21353,PHI:123799,UniProt,A0A384JER6,GenBank,ATZ48907,,,B05.10,Mtp1 (XP_001550923.1),chromosome BCIN04,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,mitochondrial transport proteins,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced; defective,,no,Congo red (CR); NaCl; KCl; H2O2; caffeine; paraquat,Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; caffeine: CHEBI:27732; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,NN,36675846,PubMed,10.3390/jof9010025,J Fungi (Basel). 2022 Dec 23;9(1):25. doi: 10.3390/jof9010025,changjun-chen@njau.edu.cn,"The BcMtp1 deletion mutant phenotype was strikingly defective in vegetative development, conidiation, and sclerotia production; ΔBcMtp1 displayed compromised virulence on various host-plant tissues.",W Shao 2022,2022,1 gene,Shao-2022-Function of the Mitochondrial Transp,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21354,PHI:123799,UniProt,A0A384JER6,GenBank,ATZ48907,,,B05.10,Mtp1 (XP_001550923.1),chromosome BCIN04,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,mitochondrial transport proteins,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced; defective,,no,Congo red (CR); NaCl; KCl; H2O2; caffeine; paraquat,Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; caffeine: CHEBI:27732; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,NN,36675846,PubMed,10.3390/jof9010025,J Fungi (Basel). 2022 Dec 23;9(1):25. doi: 10.3390/jof9010025,changjun-chen@njau.edu.cn,"The BcMtp1 deletion mutant phenotype was strikingly defective in vegetative development, conidiation, and sclerotia production; ΔBcMtp1 displayed compromised virulence on various host-plant tissues.",W Shao 2022,2022,1 gene,Shao-2022-Function of the Mitochondrial Transp,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21355,PHI:123799,UniProt,A0A384JER6,GenBank,ATZ48907,,,B05.10,Mtp1 (XP_001550923.1),chromosome BCIN04,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,mitochondrial transport proteins,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced; defective,,no,Congo red (CR); NaCl; KCl; H2O2; caffeine; paraquat,Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; KCl: CHEBI:32588; H2O2: CHEBI:16240; caffeine: CHEBI:27732; paraquat: CHEBI:34905,,,,,gene deletion: full; gene complementation,,,NN,36675846,PubMed,10.3390/jof9010025,J Fungi (Basel). 2022 Dec 23;9(1):25. doi: 10.3390/jof9010025,changjun-chen@njau.edu.cn,"The BcMtp1 deletion mutant phenotype was strikingly defective in vegetative development, conidiation, and sclerotia production; ΔBcMtp1 displayed compromised virulence on various host-plant tissues.",W Shao 2022,2022,1 gene,Shao-2022-Function of the Mitochondrial Transp,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21356,PHI:123800,UniProt,J9VRI9,GenBank,AFR97072,,,H99,Fbp8 (CNAG_04341),chromosome 9,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,F-box proteins,,,ergosterol biosynthesis pathway,reduced virulence,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2; NaNO2; caspofungin; amphotericin B; fluconazole,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240; NaNO2: CHEBI:78870; amphotericin B: CHEBI:2682; caspofungin: CHEBI:474180; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,NN,36547592,PubMed,10.3390/jof8121259,J Fungi (Basel). 2022 Nov 29;8(12):1259. doi: 10.3390/jof8121259,xuech@njms.rutgers.,"Mice infected with fbp8D mutant succumbed to infection within 32 and 38 days post-inoculation, while those infected with wild type strain died within 25 days.",C Cao 2022,2022,3 genes,Cao-2022-Multiple F-Box Proteins Collectively,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21357,PHI:123801,UniProt,J9VEP9,GenBank,AFR92822,,,H99,Fbp4 (CNAG_00693),chromosome 1,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,F-box proteins,,,ergosterol biosynthesis pathway,reduced virulence,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2; NaNO2; caspofungin; amphotericin B; fluconazole,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240; NaNO2: CHEBI:78870; amphotericin B: CHEBI:2682; caspofungin: CHEBI:474180; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,NN,36547592,PubMed,10.3390/jof8121259,J Fungi (Basel). 2022 Nov 29;8(12):1259. doi: 10.3390/jof8121259,xuech@njms.rutgers.,"The fbp4D-infected mice survival to 54 dpi, while those infected with wild type strain died within 25 days.",C Cao 2022,2022,3 genes,Cao-2022-Multiple F-Box Proteins Collectively,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21358,PHI:123802,UniProt,J9VS75,GenBank,AFR94555,,,H99,Fbp11 (CNAG_05294),chromosome 4,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,F-box proteins,,,ergosterol biosynthesis pathway,reduced virulence,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2; NaNO2; caspofungin; amphotericin B; fluconazole,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240; NaNO2: CHEBI:78870; amphotericin B: CHEBI:2682; caspofungin: CHEBI:474180; fluconazole: CHEBI:46081,,,,,gene deletion: full; gene complementation,,,NN,36547592,PubMed,10.3390/jof8121259,J Fungi (Basel). 2022 Nov 29;8(12):1259. doi: 10.3390/jof8121259,xuech@njms.rutgers.,"Mice infected with fbp811 mutant succumbed to infection within 32 and 38 days post-inoculation, while those infected with wild type strain died within 25 days.",C Cao 2022,2022,3 genes,Cao-2022-Multiple F-Box Proteins Collectively,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21359,PHI:123801,UniProt,J9VEP9,GenBank,AFR92822,,,H99,Fbp4 (CNAG_00693),chromosome 1,,,,,PHI:123802,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,F-box proteins,,,ergosterol biosynthesis pathway,loss of pathogenicity,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2; NaNO2; caspofungin; amphotericin B; fluconazole,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240; NaNO2: CHEBI:78870; amphotericin B: CHEBI:2682; caspofungin: CHEBI:474180; fluconazole: CHEBI:46081,,,,,gene deletion: full,,,NN,36547592,PubMed,10.3390/jof8121259,J Fungi (Basel). 2022 Nov 29;8(12):1259. doi: 10.3390/jof8121259,xuech@njms.rutgers.,Mice infected with the fbp4D fbp11D double mutant survived to the termination point of the experiment (60 dpi) with no visible symptoms.,C Cao 2022,2022,3 genes,Cao-2022-Multiple F-Box Proteins Collectively,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21360,PHI:123802,UniProt,J9VS75,GenBank,AFR94555,,,H99,Fbp11 (CNAG_05294),chromosome 4,,,,,PHI:123801,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,F-box proteins,,,ergosterol biosynthesis pathway,loss of pathogenicity,,,,,,,,,,no,calcofluor white (CFW); Congo red (CR); NaCl; sorbitol; KCl; SDS; H2O2; NaNO2; caspofungin; amphotericin B; fluconazole,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; NaCl: CHEBI:26710; sorbitol: CHEBI:30911; KCl: CHEBI:32588; SDS: CHEBI:8984; H2O2: CHEBI:16240; NaNO2: CHEBI:78870; amphotericin B: CHEBI:2682; caspofungin: CHEBI:474180; fluconazole: CHEBI:46081,,,,,gene deletion: full,,,NN,36547592,PubMed,10.3390/jof8121259,J Fungi (Basel). 2022 Nov 29;8(12):1259. doi: 10.3390/jof8121259,xuech@njms.rutgers.,Mice infected with the fbp4D fbp11D double mutant survived to the termination point of the experiment (60 dpi) with no visible symptoms.,C Cao 2022,2022,3 genes,Cao-2022-Multiple F-Box Proteins Collectively,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21361,PHI:123803,UniProt,B8NL91,GenBank,QMW32826,,,NRRL3357,HacA (AFLA_089270),chromosome 5,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),B73 line,,,kernel,putative transcription factor,,,,unaffected pathogenicity,,,,,,,,reduced; defective,,no,menadione,menadione: CHEBI:28869,,,,,gene deletion: full,,,NN,36675939,PubMed,10.3390/jof9010118,J Fungi (Basel). 2023 Jan 14;9(1):118. doi: 10.3390/jof9010118,gilbert@usda.gov,"AFLA_089270, a CP2 transcription factor, did not alter aflatoxin accumulation in kernels, indicating unaffected pathogenicity.",M K Gilbert 2023,2023,8 genes,Gilbert-2023-Putative Core Transcription Facto,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21362,PHI:123804,UniProt,B8N9Y0,,,,,,AFLA_112760,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),B73 line,,,kernel,putative transcription factor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,menadione,menadione: CHEBI:28869,,,,,gene deletion: full,,,NN,36675939,PubMed,10.3390/jof9010118,J Fungi (Basel). 2023 Jan 14;9(1):118. doi: 10.3390/jof9010118,gilbert@usda.gov,"AFLA_112760, a CP2 transcription factor, did not alter aflatoxin accumulation in kernels, indicating unaffected pathogenicity.",M K Gilbert 2023,2023,8 genes,Gilbert-2023-Putative Core Transcription Facto,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21363,PHI:123805,UniProt,B8N3R1,,,,,,AFLA_031450,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),B73 line,,,kernel,putative transcription factor,,,,reduced virulence,,,,,,,,wild type,,no,menadione,menadione: CHEBI:28869,,,,,gene deletion: full,,,NN,36675939,PubMed,10.3390/jof9010118,J Fungi (Basel). 2023 Jan 14;9(1):118. doi: 10.3390/jof9010118,gilbert@usda.gov,"AFLA_031450, a CP2 transcription factor, reduced aflatoxin accumulation in kernels, indicating reduced pathogenicity.",M K Gilbert 2023,2023,8 genes,Gilbert-2023-Putative Core Transcription Facto,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21364,PHI:123806,UniProt,B8NYA0,,,,,,AFLA_010700,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),B73 line,,,kernel,putative transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,menadione,menadione: CHEBI:28869,,,,,gene deletion: full,,,NN,36675939,PubMed,10.3390/jof9010118,J Fungi (Basel). 2023 Jan 14;9(1):118. doi: 10.3390/jof9010118,gilbert@usda.gov,"AFLA_010700, a CP2 transcription factor, did not alter aflatoxin accumulation in kernels, indicating unaffected pathogenicity.",M K Gilbert 2023,2023,8 genes,Gilbert-2023-Putative Core Transcription Facto,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21365,PHI:123807,UniProt,B8N0R8,GenBank,QMW28573,,,NRRL3357,AFLA_026030,chromosome 2,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),B73 line,,,kernel,putative transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,menadione,menadione: CHEBI:28869,,,,,gene deletion: full,,,NN,36675939,PubMed,10.3390/jof9010118,J Fungi (Basel). 2023 Jan 14;9(1):118. doi: 10.3390/jof9010118,gilbert@usda.gov,"AFLA_026030, a CP2 transcription factor, did not alter aflatoxin accumulation in kernels, indicating unaffected pathogenicity.",M K Gilbert 2023,2023,8 genes,Gilbert-2023-Putative Core Transcription Facto,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21366,PHI:123808,UniProt,B8NJ64,GenBank,QMW34709,,,NRRL3357,AFLA_064960,chromosome 6,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),B73 line,,,kernel,putative transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,menadione,menadione: CHEBI:28869,,,,,gene deletion: full,,,NN,36675939,PubMed,10.3390/jof9010118,J Fungi (Basel). 2023 Jan 14;9(1):118. doi: 10.3390/jof9010118,gilbert@usda.gov,"AFLA_064960, a CP2 transcription factor, did not alter aflatoxin accumulation in kernels, indicating unaffected pathogenicity.",M K Gilbert 2023,2023,8 genes,Gilbert-2023-Putative Core Transcription Facto,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21367,PHI:123809,UniProt,B8N8A5,,,,,,AFLA_106990,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),B73 line,,,kernel,putative transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,menadione,menadione: CHEBI:28869,,,,,gene deletion: full,,,NN,36675939,PubMed,10.3390/jof9010118,J Fungi (Basel). 2023 Jan 14;9(1):118. doi: 10.3390/jof9010118,gilbert@usda.gov,"AFLA_106990, a CP2 transcription factor, did not alter aflatoxin accumulation in kernels, indicating unaffected pathogenicity.",M K Gilbert 2023,2023,8 genes,Gilbert-2023-Putative Core Transcription Facto,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21368,PHI:123810,UniProt,B8NNB5,,,,,,AFLA_127260,,,,,,,5059,Aspergillus flavus,,CA14,ear rot (corn); yellow mold (peanut),monocots,4577,Zea mays (related: maize),B73 line,,,kernel,putative transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,menadione,menadione: CHEBI:28869,,,,,gene deletion: full,,,NN,36675939,PubMed,10.3390/jof9010118,J Fungi (Basel). 2023 Jan 14;9(1):118. doi: 10.3390/jof9010118,gilbert@usda.gov,"AFLA_127260, a CP2 transcription factor, did not alter aflatoxin accumulation in kernels, indicating unaffected pathogenicity.",M K Gilbert 2023,2023,8 genes,Gilbert-2023-Putative Core Transcription Facto,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21369,PHI:123811,UniProt,Q59UY7,GenBank,AOW30969,,,SC5314,sef1,chromosome R,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,transcription factors,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36711857,PubMed,10.1101/2023.01.11.523704,bioRxiv. 2023 Jan 12:2023.01.11.523704. doi: 10.1101/2023.01.11.523704. Preprint,damian-krysan@uiowa.edu,Deletion of transcription factor that activate iron uptake gene (SEF1) have no effect on virulence in a mouse model of oral candidiasis.,N V Solis 2023,2023,2 genes,Solis-2023-Candida albicans oropharyngeal infe,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21370,PHI:123812,UniProt,A0A1D8PN26,GenBank,AOW29536,,,SC5314,hap5,chromosome 5,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,kidney,transcription factors,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36711857,PubMed,10.1101/2023.01.11.523704,bioRxiv. 2023 Jan 12:2023.01.11.523704. doi: 10.1101/2023.01.11.523704. Preprint,damian-krysan@uiowa.edu,Deletion of transcription factor that activate iron uptake gene (HAP5) have no effect on virulence in a mouse model of oral candidiasis.,N V Solis 2023,2023,2 genes,Solis-2023-Candida albicans oropharyngeal infe,BATCH_119A,2023-02-01,MC,,,,,,,,,,,,,
,,Record 21371,PHI:123813,UniProt,A0A0H3KC25,GenBank,ATC67255,,,,purN,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,phosphoribosylglycinamide formyltransferase,,,,reduced virulence,,,,,,,,,,no,ampicillin; anhydrotetracycline; vancomycin; gentamicin; levofloxacin,ampicillin: CHEBI:28971; anhydrotetracycline: CHEBI:17146; vancomycin: CHEBI:28001; gentamicin: CHEBI:17833; levofloxacin: CHEBI:63598,,,,,gene deletion: full,,,NN,36551359,PubMed,10.3390/antibiotics11121702,Antibiotics (Basel). 2022 Nov 25;11(12):1702. doi: 10.3390/antibiotics11121702,yzhang207@zju.edu.cn,The LD50 of the ΔpurN for BALB/c mice was significantly higher than that of the parental strain.,Q Peng 2022,2022,1 gene,Peng-2022-PurN Is Involved in Antibiotic Toler,BATCH_119A,2023-02-01,,,,,,,,,,,,,,
,,Record 21372,PHI:123814,UniProt,A7F1G6,GenBank,EDN95558,,,1980,MRT4 (SS1G_11436),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,mRNA turnover protein 4,,,,loss of pathogenicity,,,,,no necrotic lesions,,,reduced; defective,,no,H2O2; sorbitol; NaCl; SDS; glucose; KCl,H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; SDS: CHEBI:8984; glucose: CHEBI:17234; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,36839553,PubMed,10.3390/pathogens12020281,Pathogens. 2023 Feb 8;12(2):281,xstone0505@hunau.edu.cn,Knockdown of SsMRT4 resulted in retard mycelia growth and complete loss of pathogenicity.,C Yang 2023,2023,1 gene,Yang-2023-mRNA Turnover Protein 4 Is Vital for,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21373,PHI:123814,UniProt,A7F1G6,GenBank,EDN95558,,,1980,MRT4 (SS1G_11436),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,mRNA turnover protein 4,,,,loss of pathogenicity,,,,,no necrotic lesions,,,reduced; defective,,no,H2O2; sorbitol; NaCl; SDS; glucose; KCl,H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; SDS: CHEBI:8984; glucose: CHEBI:17234; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,36839553,PubMed,10.3390/pathogens12020281,Pathogens. 2023 Feb 8;12(2):281,xstone0505@hunau.edu.cn,Knockdown of SsMRT4 resulted in retard mycelia growth and complete loss of pathogenicity.,C Yang 2023,2023,1 gene,Yang-2023-mRNA Turnover Protein 4 Is Vital for,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21374,PHI:123815,UniProt,Q99ZT1,GenBank,AAK33973,,,SF370,Spy1094,,,,,,,1314,Streptococcus pyogenes,,SF370,infection,primates,9606,Homo sapiens (related: human),,,,blood,N-acetylglucosamine (GlcNAc) deacetylases,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36838272,PubMed,10.3390/microorganisms11020305,Microorganisms. 2023 Jan 24;11(2):305,t.proft@auckland.ac.nz,Survival of S. pyogenes Δspy1094 significantly decreased during incubation and were almost completely killed within the first 1.5 h.,T Aspell 2023,2023,4 genes,Aspell-2023-The Cell Wall Deacetylases Spy1094,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21375,PHI:123816,UniProt,Q99Z68,GenBank,AAK34197,,,SF370,Spy1370,,,,,,,1314,Streptococcus pyogenes,,SF370,infection,primates,9606,Homo sapiens (related: human),,,,blood,N-acetylglucosamine (GlcNAc) deacetylases,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36838272,PubMed,10.3390/microorganisms11020305,Microorganisms. 2023 Jan 24;11(2):305,t.proft@auckland.ac.nz,Survival of S. pyogenes Δspy1370 significantly decreased during incubation and were almost completely killed within the first 1.5 h.,T Aspell 2023,2023,4 genes,Aspell-2023-The Cell Wall Deacetylases Spy1094,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21376,PHI:123815,UniProt,Q99ZT1,GenBank,AAK33973,,,SF370,Spy1094,,,,,,,1314,Streptococcus pyogenes,,SF370,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,N-acetylglucosamine (GlcNAc) deacetylases,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36838272,PubMed,10.3390/microorganisms11020305,Microorganisms. 2023 Jan 24;11(2):305,t.proft@auckland.ac.nz,"Compared to infection with wildtype S. pyogenes, deletion of spy1094 substantially increased survival of infected G. mellonella larvae.",T Aspell 2023,2023,4 genes,Aspell-2023-The Cell Wall Deacetylases Spy1094,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21377,PHI:123816,UniProt,Q99Z68,GenBank,AAK34197,,,SF370,Spy1370,,,,,,,1314,Streptococcus pyogenes,,SF370,infection,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,N-acetylglucosamine (GlcNAc) deacetylases,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36838272,PubMed,10.3390/microorganisms11020305,Microorganisms. 2023 Jan 24;11(2):305,t.proft@auckland.ac.nz,"Compared to infection with wildtype S. pyogenes, deletion of spy1370 substantially increased survival of infected G. mellonella larvae.",T Aspell 2023,2023,4 genes,Aspell-2023-The Cell Wall Deacetylases Spy1094,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21378,PHI:123817,,no data found,,,,,,Spy1094,,,,,,,1358,Lactococcus lactis,416870,MG1363,endocarditis,primates,9606,Homo sapiens (related: human),,,,blood,N-acetylglucosamine (GlcNAc) deacetylases,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,other evidence: transgenic,,,NN,36838272,PubMed,10.3390/microorganisms11020305,Microorganisms. 2023 Jan 24;11(2):305,t.proft@auckland.ac.nz,Mutant survived in whole human blood with a ~2.2-fold increase in CFU for L. lactis spy1094.,T Aspell 2023,2023,4 genes,Aspell-2023-The Cell Wall Deacetylases Spy1094,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21379,PHI:123818,,no data found,,,,,,Spy1370,,,,,,,1358,Lactococcus lactis,416870,MG1363,endocarditis,primates,9606,Homo sapiens (related: human),,,,blood,N-acetylglucosamine (GlcNAc) deacetylases,,,,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,other evidence: transgenic,,,NN,36838272,PubMed,10.3390/microorganisms11020305,Microorganisms. 2023 Jan 24;11(2):305,t.proft@auckland.ac.nz,Mutant survived in whole human blood with a ~3-fold increase in CFU for L. lactis spy1370.,T Aspell 2023,2023,4 genes,Aspell-2023-The Cell Wall Deacetylases Spy1094,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21380,PHI:123817,,no data found,,,,,,Spy1094,,,,,,,1358,Lactococcus lactis,416870,MG1363,endocarditis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,N-acetylglucosamine (GlcNAc) deacetylases,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,other evidence: transgenic,,,NN,36838272,PubMed,10.3390/microorganisms11020305,Microorganisms. 2023 Jan 24;11(2):305,t.proft@auckland.ac.nz,L. lactis expressing Spy1094 killed 60% of the larvae after five days compared to the 100% survival of larvae infected with wild type.,T Aspell 2023,2023,4 genes,Aspell-2023-The Cell Wall Deacetylases Spy1094,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21381,PHI:123818,,no data found,,,,,,Spy1370,,,,,,,1358,Lactococcus lactis,416870,MG1363,endocarditis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,N-acetylglucosamine (GlcNAc) deacetylases,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,other evidence: transgenic,,,NN,36838272,PubMed,10.3390/microorganisms11020305,Microorganisms. 2023 Jan 24;11(2):305,t.proft@auckland.ac.nz,L. lactis expressing Spy1370 killed 50% of the larvae after five days compared to the 100% survival of larvae infected with wild type.,T Aspell 2023,2023,4 genes,Aspell-2023-The Cell Wall Deacetylases Spy1094,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21382,PHI:123819,,no data found,,,,,,GAPR1,,,,,,,45133,Lasiodiplodia theobromae,,CSS-01,canker (grape),eudicots,29760,Vitis vinifera (related: wine grape),cv. Summer Black,,,shoot,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36836303,PubMed,10.3390/jof9020188,J Fungi (Basel). 2023 Jan 31;9(2):188,yanjiye@ipepbaafs.cn,The pathogenicity test on detached grapevine shoots showed that LtGAPR1-OE had decreased disease symptoms and the silenced transformants had increased disease symptoms.,C Huang 2023,2023,1 gene,Huang-2023-LtGAPR1 Is a Novel Secreted Effecto,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21383,PHI:123819,,no data found,,,,,,GAPR1,,,,,,,45133,Lasiodiplodia theobromae,,CSS-01,canker (grape),eudicots,29760,Vitis vinifera (related: wine grape),cv. Summer Black,,,shoot,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,36836303,PubMed,10.3390/jof9020188,J Fungi (Basel). 2023 Jan 31;9(2):188,yanjiye@ipepbaafs.cn,The pathogenicity test on detached grapevine shoots showed that LtGAPR1-OE had decreased disease symptoms and the silenced transformants had increased disease symptoms.,C Huang 2023,2023,1 gene,Huang-2023-LtGAPR1 Is a Novel Secreted Effecto,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21384,PHI:123820,UniProt,A0A4E9DG31,,,,,,AP1σ (FGSG_10034),,,,AP1β (FGSG_06317); AP1u (FGSG_17141); AP1γ (FGSG_01893),,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; coleoptile,clathrin adaptor,,,,loss of pathogenicity,,,,,,reduced,reduced,reduced,,no,sorbitol; calcofluor white; sodium dodecylsulfate (SDS); Congo red; KCl,calcofluor white (CFW): CHEBI:50011; Congo red (CR): CHEBI:34653; SDS: CHEBI:8984; D-sorbitol: CHEBI:17924; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,36836259,PubMed,10.3390/jof9020145,J Fungi (Basel). 2023 Jan 21;9(2):145,zhw@mju.edu.cn,"Disruption of FgAP1σ causes seriously impaired fungal vegetative growth, conidiogenesis, sexual development, pathogenesis, and deoxynivalenol (DON) production.",C Wu 2023,2023,1 gene,Wu-2023-FgAP1(σ) Is Critical for Vegetative Gr,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21385,PHI:123821,UniProt,Q5BH63,GenBank,EAA65295,,,FGSC A4,svfA,chromosome 8,,,,,,162425,Aspergillus nidulans,,,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,survival factor A,,,MAPK phosphorylation,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36836258,PubMed,10.3390/jof9020143,J Fungi (Basel). 2023 Jan 21;9(2):143,sptemple@iupui.edu,T-cell-deficient zebrafish were more susceptible to the WT conidia (with approximately 20% mortality) than the ΔsvfA conidia (with approximately 5% mortality) at 7 dpi.,J-Y Lim 2023,2023,2 genes,Lim-2023-Survival Factor A (SvfA) Contributes,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21386,PHI:123822,UniProt,Q4WVE5,GenBank,EAL91431,,,Af293,svfA,chromosome 5,,,,,,746128,Aspergillus fumigatus,,,invasive aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,survival factor A,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36836258,PubMed,10.3390/jof9020143,J Fungi (Basel). 2023 Jan 21;9(2):143,sptemple@iupui.edu,The rate of mortality of AfsvfA overexpression was similar to the wild type.,J-Y Lim 2023,2023,2 genes,Lim-2023-Survival Factor A (SvfA) Contributes,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21387,PHI:123821,UniProt,Q5BH63,GenBank,EAA65295,,,FGSC A4,svfA,chromosome 8,,,,,,162425,Aspergillus nidulans,,,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CGD,,,lung,survival factor A,,,MAPK phosphorylation,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36836258,PubMed,10.3390/jof9020143,J Fungi (Basel). 2023 Jan 21;9(2):143,sptemple@iupui.edu,"Mice infected with WT conidia and C'svfA conidia died in the first 14 and 10 d, but a clear increase in the survival rate in the ΔsvfA-conidia-infected mice was observed in 80% of the surviving animals.",J-Y Lim 2023,2023,2 genes,Lim-2023-Survival Factor A (SvfA) Contributes,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21388,PHI:123822,UniProt,Q4WYE4,GenBank,EAL92309,,,Af293,CrpA,chromosome 3,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,alveolar macrophage,copper-exporting ATPase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36835119,PubMed,10.3390/ijms24043705,Int J Mol Sci. 2023 Feb 13;24(4):3705,nosherov@post.tau.ac.il,"ΔCrpA, in which CrpA is deleted, was reduced in virulence compared with CrpA_cont",H Werner 2023,2023,1 gene,Werner-2023-Identification and Analysis of Fun,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21389,PHI:123823,UniProt,G2XC60,GenBank,EGY16578,,,VdLs.17,VDAG_07742,chromosome 5,,,,,,27337,Verticillium dahliae,,JY,vascular wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. Favorita,,,seedling; stem,hypothetical protein,,,,reduced virulence,,,yes,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,36835042,PubMed,10.3390/ijms24043630,Int J Mol Sci. 2023 Feb 11;24(4):3630,rfan@gzu.edu.cn,"The knockout and complementation mutant revealed that the gene was not involved in mycelial growth, conidial production, or germination; the penetration ability and pathogenicity of VDAG_07742 deletion mutants were significantly reduced.",D Wang 2023,2023,1 gene,Wang-2023-Hypothetical Protein VDAG_07742 Is R,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21390,PHI:123824,UniProt,Q4WTU6,GenBank,EAL91980,,,Af293,elp3 (Afu5g06140),chromosome 5,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,histone acetyltransferase,,,,unaffected pathogenicity,,,,,,increased,,reduced,,no,H2O2; menadione; Congo red; calcofluor white (CFW); voriconazole; itraconazole,H2O2: CHEBI:16240; menadione: CHEBI:28869; congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076,,,,,gene deletion: full,,,NN,36768506,PubMed,10.3390/ijms24032179,Int J Mol Sci. 2023 Jan 22;24(3):2179,jyu1@wisc.edu,Mice infected with the Δelp3 mutant spores survived similar to those infected with the WT.,Y-H Choi 2023,2023,2 genes,Choi-2023-Functional Characterization of the G,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21391,PHI:123825,UniProt,Q4WQF6,GenBank,EAL89528,,,Af293,gcnE (Afu4g12650),chromosome 4,,,,,,746128,Aspergillus fumigatus,330879,Af293,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,lung,histone acetyltransferase,,,,reduced virulence,,,,,,reduced,,reduced; defective,,no,H2O2; menadione; Congo red; calcofluor white (CFW); voriconazole; itraconazole,H2O2: CHEBI:16240; menadione: CHEBI:28869; congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; voriconazole: CHEBI:10023; itraconazole: CHEBI:6076,,,,,gene deletion: full,,,NN,36768506,PubMed,10.3390/ijms24032179,Int J Mol Sci. 2023 Jan 22;24(3):2179,jyu1@wisc.edu,Mice infected with the ΔgcnE mutant spores survived significantly longer than those infected with the WT.,Y-H Choi 2023,2023,2 genes,Choi-2023-Functional Characterization of the G,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21392,PHI:123826,UniProt,A0A034T1N5,GenBank,GAJ65962,,,RSB1309,EvpP,,,,,,,1263550,Edwardsiella piscicida,,QL-S,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,32117819,PubMed,10.3389/fcimb.2020.00053,Front Cell Infect Microbiol. 2020 Feb 14;10:53,qinlei1978@163.com,ΔevpP was found to be attenuated for growth within macrophages and found its survival capacity was lower than WT under oxidative acid stress in vitro.,L Qin 2020,2020,1 gene,Qin-2020-Roles of EvpP in Edwardsiella piscici,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21393,PHI:123827,,no data found,,,,,,KMT3,,,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Hefeng 47,,,hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,,reduced,,reduced,,no,H2O2; NaCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710,,,,,gene deletion: full,,,NN,36748674,PubMed,10.1111/mpp.13301,Mol Plant Pathol. 2023 Apr;24(4):346-358,smdong@njau.edu.cn,Deletion of PsKMT3 led to asexual development and pathogenicity defects.,H Chen 2023,2023,1 gene,Chen-2023-The SET domain protein PsKMT3 regula,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21394,PHI:123828,UniProt,G1FE63,GenBank,AEL17637,,,HY9901,AcfA,,,,,,,663,Vibrio alginolyticus,,HY9901,vibriosis,bony fishes,94232,Epinephelus coioides (related: orange-spotted grouper),,,,,accessory colonization factor protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,29292001,PubMed,10.1016/j.vetmic.2017.11.016,Vet Microbiol. 2018 Jan;213:35-41,shuanghucai@gmail.com,"An acfA mutant showed a similar growth level, an obvious decrease in swarming motility and the activity of ECPase, a higher LD50 value by intraperitoneal injection of grouper fish compared to that of the wild-type.",S Cai 2017,2017,1 gene,Cai-2018-AcfA is an essential regulator for pa,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21395,PHI:123829,,no data found,GenBank,MVNS00000000,,,1104-7,CfPMK1,,,,,,,690256,Colletotrichum fructicola,,1104-6,anthracnose,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf,MAP kinase,,,MAP kinase pathway,loss of pathogenicity,,,,,no lesion,reduced; defective,,reduced,wild type,no,H2O2; NaCl; Congo red; SDS; KCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,31164876,PubMed,10.3389/fmicb.2019.01070,Front Microbiol. 2019 May 21;10:1070,rongzh@nwsuaf.edu.cn,CfPMK1 gene deletion mutant was slightly reduced in radial growth rate and formed deformed perithecia that were smaller in size and more compactly organized relative to wild type.,X Liang 2019,2019,1 gene,Liang-2019-The MAP Kinase CfPMK1 Is a Key Regu,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21396,PHI:123829,,no data found,GenBank,MVNS00000000,,,1104-7,CfPMK1,,,,,,,690256,Colletotrichum fructicola,,1104-6,anthracnose,eudicots,23211,Pyrus communis (related: Pear),,,,fruit,MAP kinase,,,MAP kinase pathway,loss of pathogenicity,,,,,no lesion,reduced; defective,,reduced,wild type,no,H2O2; NaCl; Congo red; SDS; KCl,H2O2: CHEBI:16240; NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,31164876,PubMed,10.3389/fmicb.2019.01070,Front Microbiol. 2019 May 21;10:1070,rongzh@nwsuaf.edu.cn,CfPMK1 gene deletion mutant was slightly reduced in radial growth rate and formed deformed perithecia that were smaller in size and more compactly organized relative to wild type.,X Liang 2019,2019,1 gene,Liang-2019-The MAP Kinase CfPMK1 Is a Key Regu,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21397,PHI:123830,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,histone acetyltransferase,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,reduced,no,NaCl; Congo red; SDS; KCl; calcofluor white (CFW); H2O2; DTT,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; KCl: CHEBI:32588; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,NN,34248895,PubMed,10.3389/fmicb.2021.680415,Front Microbiol. 2021 Jun 23;12:680415,T20061078@csuft.edu.cn,ΔCfgcn5 showed no lesions compared with the large and typical lesions caused by WT and ΔCfgcn5/CfGCN5.,S Zhang 2021,2021,1 gene,Zhang-2021-The Histone Acetyltransferase CfGcn,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21398,PHI:123830,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,histone acetyltransferase,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,reduced,no,NaCl; Congo red; SDS; KCl; calcofluor white (CFW); H2O2; DTT,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; KCl: CHEBI:32588; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,NN,34248895,PubMed,10.3389/fmicb.2021.680415,Front Microbiol. 2021 Jun 23;12:680415,T20061078@csuft.edu.cn,ΔCfgcn5 showed no lesions compared with the large and typical lesions caused by WT and ΔCfgcn5/CfGCN5.,S Zhang 2021,2021,1 gene,Zhang-2021-The Histone Acetyltransferase CfGcn,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21399,PHI:123830,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,Deletion of the NLS region,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,histone acetyltransferase,,,,reduced virulence,,,,,some lesion,reduced,,reduced,,no,,,,,,,gene deletion: partial,,,NN,34248895,PubMed,10.3389/fmicb.2021.680415,Front Microbiol. 2021 Jun 23;12:680415,T20061078@csuft.edu.cn,ΔNLS showed moderate growth and conidiation rates between that of ΔCfgcn5 and WT and shows some lesions but fewer than WT.,S Zhang 2021,2021,1 gene,Zhang-2021-The Histone Acetyltransferase CfGcn,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21400,PHI:123830,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,Deletion of the NLS region,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,histone acetyltransferase,,,,reduced virulence,,,,,some lesion,reduced,,reduced,,no,,,,,,,gene deletion: partial,,,NN,34248895,PubMed,10.3389/fmicb.2021.680415,Front Microbiol. 2021 Jun 23;12:680415,T20061078@csuft.edu.cn,ΔNLS showed moderate growth and conidiation rates between that of ΔCfgcn5 and WT and shows some lesions but fewer than WT.,S Zhang 2021,2021,1 gene,Zhang-2021-The Histone Acetyltransferase CfGcn,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21401,PHI:123830,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,Deletion of the HAT region,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,histone acetyltransferase,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,34248895,PubMed,10.3389/fmicb.2021.680415,Front Microbiol. 2021 Jun 23;12:680415,T20061078@csuft.edu.cn,ΔHAT produced no lesions like ΔCfgcn5 and failed to restore the ΔCfgcn5 mutant in growth and conidiation.,S Zhang 2021,2021,1 gene,Zhang-2021-The Histone Acetyltransferase CfGcn,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21402,PHI:123830,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,Deletion of the HAT region,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,histone acetyltransferase,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,34248895,PubMed,10.3389/fmicb.2021.680415,Front Microbiol. 2021 Jun 23;12:680415,T20061078@csuft.edu.cn,ΔHAT produced no lesions like ΔCfgcn5 and failed to restore the ΔCfgcn5 mutant in growth and conidiation.,S Zhang 2021,2021,1 gene,Zhang-2021-The Histone Acetyltransferase CfGcn,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21403,PHI:123830,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,Deletion of the Bromo region,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,histone acetyltransferase,,,,reduced virulence,,,,,some lesion,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,34248895,PubMed,10.3389/fmicb.2021.680415,Front Microbiol. 2021 Jun 23;12:680415,T20061078@csuft.edu.cn,ΔBromo produced some lesions but fewer than WT and restore the growth and conidiation.,S Zhang 2021,2021,1 gene,Zhang-2021-The Histone Acetyltransferase CfGcn,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21404,PHI:123830,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,Deletion of the Bromo region,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,histone acetyltransferase,,,,reduced virulence,,,,,some lesion,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,34248895,PubMed,10.3389/fmicb.2021.680415,Front Microbiol. 2021 Jun 23;12:680415,T20061078@csuft.edu.cn,ΔBromo produced some lesions but fewer than WT and restore the growth and conidiation.,S Zhang 2021,2021,1 gene,Zhang-2021-The Histone Acetyltransferase CfGcn,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21405,PHI:123831,UniProt,L2GFX7,GenBank,KAF4488589,,,Nara gc5,Set1,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,H3K4 methyltransferase,,,,reduced virulence,,,,,some lesion,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35448594,PubMed,10.3390/jof8040363,J Fungi (Basel). 2022 Apr 1;8(4):363,t20061078@csuft.edu.cn,"CfSET1 was deleted and participates in the growth, conidiation, appressorium formation, and pathogenicity of this fungal pathogen.",Y Gao 2022,2022,1 gene,Gao-2022-H3K4 Methyltransferase CfSet1 Is Requ,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21406,PHI:123832,UniProt,A0A8S9CXG5,GenBank,KAE9575508,,,CGMCC3.17371,Vam7,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,t-SNARE protein,,,,reduced virulence,,,,,some lesion,reduced,,reduced,,no,Congo red; SDS; calcofluor white (CFW); DTT; tunicamycin;,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; KCl: CHEBI:32588; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699,,,,,gene deletion: full; gene complementation,,,NN,34721333,PubMed,10.3389/fmicb.2021.736066,Front Microbiol. 2021 Oct 14;12:736066,T20061078@csuft.edu.cn,The lesion area on wounded leaf shows the mutant strain ΔCfvam7 was significantly lower than in the wild-type and complementary strains (p < 0.01).,S Li 2021,2021,1 gene,Li-2021-The SNARE Protein CfVam7 Is Required f,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21407,PHI:123832,UniProt,A0A8S9CXG5,GenBank,KAE9575508,,,CGMCC3.17371,Vam7,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,t-SNARE protein,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,Congo red; SDS; calcofluor white (CFW); DTT; tunicamycin;,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; KCl: CHEBI:32588; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; dithiothreitol: CHEBI:42170; tunicamycin: CHEBI:29699,,,,,gene deletion: full; gene complementation,,,NN,34721333,PubMed,10.3389/fmicb.2021.736066,Front Microbiol. 2021 Oct 14;12:736066,T20061078@csuft.edu.cn,On unwounded leaf the pathogenicity of the mutant strain was completely lost compared with that in the wild-type and complementary strains,S Li 2021,2021,1 gene,Li-2021-The SNARE Protein CfVam7 Is Required f,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21408,PHI:123832,UniProt,A0A8S9CXG5,GenBank,KAE9575508,,,CGMCC3.17371,Vam7,,SNARE domain deletion,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,t-SNARE protein,,,,loss of pathogenicity,,,,,no lesion,,,reduced,,no,,,,,,,gene deletion: partial,,,NN,34721333,PubMed,10.3389/fmicb.2021.736066,Front Microbiol. 2021 Oct 14;12:736066,T20061078@csuft.edu.cn,"The pathogenicity test showed that the SNARE domain deletion strain could not induce disease spots on the leaves of Ca. oleifera with or without wound, similar to the mutant strain ΔCfvam7.",S Li 2021,2021,1 gene,Li-2021-The SNARE Protein CfVam7 Is Required f,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21409,PHI:123832,UniProt,A0A8S9CXG5,GenBank,KAE9575508,,,CGMCC3.17371,Vam7,,Phox Homolog deletion,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,t-SNARE protein,,,,reduced virulence,,,,,some lesion,,,reduced,,no,,,,,,,gene deletion: partial,,,NN,34721333,PubMed,10.3389/fmicb.2021.736066,Front Microbiol. 2021 Oct 14;12:736066,T20061078@csuft.edu.cn,The PX domain deletion strain could induce disease spots on a leaf with or without a wound but the sizes of the disease spots were significantly lower compared with those of wild-type and complementary strains (p < 0.01).,S Li 2021,2021,1 gene,Li-2021-The SNARE Protein CfVam7 Is Required f,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21410,PHI:123833,UniProt,A0A7J6IL04,GenBank,KAF4477393,,,Nara gc5,Vps35,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,vacuolar protein sorting-associated protein,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,Congo red; calcofluor white (CFW),Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,36031614,PubMed,10.1186/s12863-022-01084-4,BMC Genom Data. 2022 Aug 28;23(1):68,T20061078@csuft.edu.cn,"CfVPS35 gene deleted, results in reduced mycelial growth, conidiation, and response to cell wall stresses; CfVps35 was required for C. fructicola virulence on tea oil leaves.",X-Y Li 2022,2022,1 gene,"Li-2022-Retromer subunit, CfVps35 is required",BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21411,PHI:123834,UniProt,A0A034T0A1,GenBank,GAJ66221,,,RSB1309,TrxH,,,,,,,1263550,Edwardsiella piscicida,,TX01,gastroenteritis,bony fishes,8255,Paralichthys olivaceus (related: japanese flounder),,,,,thioredoxins H,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,30992061,PubMed,10.1186/s13567-019-0645-z,Vet Res. 2019 Apr 15;50(1):26,sdmlzw@126.com,"The survival rate of TX01ΔtrxH-infected fish was 43.3%, which was significantly higher than that of TX01-infected fish (13.3%).",B-Y Wang 2019,2019,1 gene,Wang-2019-Thioredoxin H (TrxH) contributes to,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21412,PHI:123836,UniProt,Q9I4X3,GenBank,AAG04385,,,PAO1,pqsA,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,adult,anthranilate--CoA ligase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36800381,PubMed,10.1371/journal.ppat.1010925,PLoS Pathog. 2023 Feb 17;19(2):e1010925,Patrick.secor@mso.umt.edu,ΔpqsA is less virulent against C. elegans compared to wild-type P. aeruginosa.,C M Schwartzkopf 2023,2023,2 genes (second gene entry deleted as virus),Schwartzkopf-2023-Tripartite interactions betw,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21413,PHI:123837,UniProt,A0A411H3X1,GenBank,QBB12949,,,MS-18-199,luxS,,,,,,,1263550,Edwardsiella piscicida,,EIB202,gastroenteritis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,S-ribosylhomocysteine lyase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,32071069,PubMed,10.1128/IAI.00907-19,Infect Immun. 2020 Apr 20;88(5):e00907-19,xpwang@sdau.edu.cn.,The 50% lethal dose (LD50) of the E. piscicida ΔluxS strain for zebrafish was significantly higher than that of the wild-type strain.,Y Sun 2020,2020,1 gene,Sun-2020-LuxS_AI-2 Quorum Sensing System in Ed,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21414,PHI:123838,UniProt,A0A7T5QMM8,GenBank,QQG27614,,,2A,metC,,,,,,,554,Pectobacterium carotovorum,1218933,subsp. carotovorum strain Pcc21,soft rot; blackleg disease,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,,cystathionine beta-lyase,,,methionine biosynthetic pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,36760050,PubMed,10.5423/PPJ.OA.09.2022.0135,Plant Pathol J. 2023 Feb;39(1):62-74,ewanchung@korea.ac.kr,The symptom was significantly decreased in the plant infected with ΔmetC.,S Yu 2022,2022,1 gene,Yu-2023-Disruption of the metC Gene Affects Me,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21415,PHI:123838,UniProt,A0A7T5QMM8,GenBank,QQG27614,,,2A,metC,,,,,,,554,Pectobacterium carotovorum,1218933,subsp. carotovorum strain Pcc21,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,cystathionine beta-lyase,,,methionine biosynthetic pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,36760050,PubMed,10.5423/PPJ.OA.09.2022.0135,Plant Pathol J. 2023 Feb;39(1):62-74,ewanchung@korea.ac.kr,The symptom was significantly decreased in the plant infected with ΔmetC.,S Yu 2022,2022,1 gene,Yu-2023-Disruption of the metC Gene Affects Me,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21416,PHI:123839,UniProt,A0A1W6VH00,GenBank,OK376642,,,HY9901,PykF,,,,,,,663,Vibrio alginolyticus,,HY9901,vibriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,pyruvate kinase I,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35795782,PubMed,10.3389/fvets.2022.877067,Front Vet Sci. 2022 Jun 6;9:877067,dingyuddd@163.com,LD50 of ΔpykF was 6 times higher than that of WT strain.,Z Xu 2022,2022,1 gene,Xu-2022-Characterizing the Effect of the Lysin,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21417,PHI:123840,,no data found,,,,,,GhxP,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: Pear),cv. Bartlett,,,fruit,guanine–hypoxanthine permease,,,biosynthetic pathway,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene deletion: full,,,NN,33152175,PubMed,10.1111/jam.14925,J Appl Microbiol. 2021 Jun;130(6):2018-2028,mourad@pfw.edu,Similar disease phenotypes in pears 7 days post-inoculation are observed with the parental wild type E. amylovora Ea1189 and EaΔghxP::Camr mutant.,I T Gatchell 2020,2020,1 gene,Gatchell-2020-The guanine-hypoxanthine permeas,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21418,PHI:123840,,no data found,,,,,,GhxP,,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),cv. Golden Smoothie,,,fruit,guanine–hypoxanthine permease,,,biosynthetic pathway,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene deletion: full,,,NN,33152175,PubMed,10.1111/jam.14925,J Appl Microbiol. 2021 Jun;130(6):2018-2028,mourad@pfw.edu,Disease phenotypes on immature apples 7 days post-inoculation are similar for E. amylovora Ea1189 and EaΔghxP::Camr mutant.,I T Gatchell 2020,2020,1 gene,Gatchell-2020-The guanine-hypoxanthine permeas,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21419,PHI:123841,UniProt,G4ML55,GenBank,EHA56791,,,70-15,Nst1 (MGG_06694),chromosome 1,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,nucleotide sugar transporters,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl; Congo red; SDS; calcofluor white (CFW); H2O2; sorbitol; arabinose; fructose; galactose; glucose; sucrose; xylose; maltose,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; arabinose: CHEBI:22599; fructose: CHEBI:28757; galactose: CHEBI:28260; glucose: CHEBI:17234; sucrose: CHEBI:17992; xylose: CHEBI:18222; maltose: CHEBI:17306,,,,,gene deletion: full; gene complementation,,,NN,36775579,PubMed,10.1111/mpp.13304,Mol Plant Pathol. 2023 Apr;24(4):374-390,chenxiaolin@mail.hzau.edu.cn,"NSTs played important roles in cell wall integrity, were involved in asexual development, and were required for full virulence.",D Chen 2023,2023,2 genes,Chen-2023-Two nucleotide sugar transporters ar,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21420,PHI:123842,UniProt,G4NGT7,GenBank,EHA47447,,,70-15,Nst2 (MGG_04030),chromosome 6,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,nucleotide sugar transporters,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl; Congo red; SDS; calcofluor white (CFW); H2O2; sorbitol; arabinose; fructose; galactose; glucose; sucrose; xylose; maltose,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; arabinose: CHEBI:22599; fructose: CHEBI:28757; galactose: CHEBI:28260; glucose: CHEBI:17234; sucrose: CHEBI:17992; xylose: CHEBI:18222; maltose: CHEBI:17306,,,,,gene deletion: full; gene complementation,,,NN,36775579,PubMed,10.1111/mpp.13304,Mol Plant Pathol. 2023 Apr;24(4):374-390,chenxiaolin@mail.hzau.edu.cn,"NSTs played important roles in cell wall integrity, were involved in asexual development, and were required for full virulence.",D Chen 2023,2023,2 genes,Chen-2023-Two nucleotide sugar transporters ar,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21421,PHI:123841,UniProt,G4ML55,GenBank,EHA56791,,,70-15,Nst1 (MGG_06694),chromosome 1,,,,,PHI:123842,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,nucleotide sugar transporters,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl; Congo red; SDS; calcofluor white (CFW); H2O2; sorbitol; arabinose; fructose; galactose; glucose; sucrose; xylose; maltose,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; arabinose: CHEBI:22599; fructose: CHEBI:28757; galactose: CHEBI:28260; glucose: CHEBI:17234; sucrose: CHEBI:17992; xylose: CHEBI:18222; maltose: CHEBI:17306,,,,,gene deletion: full,,,NN,36775579,PubMed,10.1111/mpp.13304,Mol Plant Pathol. 2023 Apr;24(4):374-390,chenxiaolin@mail.hzau.edu.cn,"NSTs played important roles in cell wall integrity, were involved in asexual development, and were required for full virulence.",D Chen 2023,2023,2 genes,Chen-2023-Two nucleotide sugar transporters ar,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21422,PHI:123842,UniProt,G4NGT7,GenBank,EHA47447,,,70-15,Nst2 (MGG_04030),chromosome 6,,,,,PHI:123841,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,nucleotide sugar transporters,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl; Congo red; SDS; calcofluor white (CFW); H2O2; sorbitol; arabinose; fructose; galactose; glucose; sucrose; xylose; maltose,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; arabinose: CHEBI:22599; fructose: CHEBI:28757; galactose: CHEBI:28260; glucose: CHEBI:17234; sucrose: CHEBI:17992; xylose: CHEBI:18222; maltose: CHEBI:17306,,,,,gene deletion: full,,,NN,36775579,PubMed,10.1111/mpp.13304,Mol Plant Pathol. 2023 Apr;24(4):374-390,chenxiaolin@mail.hzau.edu.cn,"NSTs played important roles in cell wall integrity, were involved in asexual development, and were required for full virulence.",D Chen 2023,2023,2 genes,Chen-2023-Two nucleotide sugar transporters ar,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21423,PHI:123841,UniProt,G4ML55,GenBank,EHA56791,,,70-15,Nst1 (MGG_06694),chromosome 1,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,nucleotide sugar transporters,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl; Congo red; SDS; calcofluor white (CFW); H2O2; sorbitol; arabinose; fructose; galactose; glucose; sucrose; xylose; maltose,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; arabinose: CHEBI:22599; fructose: CHEBI:28757; galactose: CHEBI:28260; glucose: CHEBI:17234; sucrose: CHEBI:17992; xylose: CHEBI:18222; maltose: CHEBI:17306,,,,,gene deletion: full; gene complementation,,,NN,36775579,PubMed,10.1111/mpp.13304,Mol Plant Pathol. 2023 Apr;24(4):374-390,chenxiaolin@mail.hzau.edu.cn,"NSTs played important roles in cell wall integrity, were involved in asexual development, and were required for full virulence.",D Chen 2023,2023,2 genes,Chen-2023-Two nucleotide sugar transporters ar,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21424,PHI:123842,UniProt,G4NGT7,GenBank,EHA47447,,,70-15,Nst2 (MGG_04030),chromosome 6,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,nucleotide sugar transporters,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl; Congo red; SDS; calcofluor white (CFW); H2O2; sorbitol; arabinose; fructose; galactose; glucose; sucrose; xylose; maltose,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; arabinose: CHEBI:22599; fructose: CHEBI:28757; galactose: CHEBI:28260; glucose: CHEBI:17234; sucrose: CHEBI:17992; xylose: CHEBI:18222; maltose: CHEBI:17306,,,,,gene deletion: full; gene complementation,,,NN,36775579,PubMed,10.1111/mpp.13304,Mol Plant Pathol. 2023 Apr;24(4):374-390,chenxiaolin@mail.hzau.edu.cn,"NSTs played important roles in cell wall integrity, were involved in asexual development, and were required for full virulence.",D Chen 2023,2023,2 genes,Chen-2023-Two nucleotide sugar transporters ar,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21425,PHI:123841,UniProt,G4ML55,GenBank,EHA56791,,,70-15,Nst1 (MGG_06694),chromosome 1,,,,,PHI:123842,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,nucleotide sugar transporters,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl; Congo red; SDS; calcofluor white (CFW); H2O2; sorbitol; arabinose; fructose; galactose; glucose; sucrose; xylose; maltose,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; arabinose: CHEBI:22599; fructose: CHEBI:28757; galactose: CHEBI:28260; glucose: CHEBI:17234; sucrose: CHEBI:17992; xylose: CHEBI:18222; maltose: CHEBI:17306,,,,,gene deletion: full,,,NN,36775579,PubMed,10.1111/mpp.13304,Mol Plant Pathol. 2023 Apr;24(4):374-390,chenxiaolin@mail.hzau.edu.cn,"NSTs played important roles in cell wall integrity, were involved in asexual development, and were required for full virulence.",D Chen 2023,2023,2 genes,Chen-2023-Two nucleotide sugar transporters ar,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21426,PHI:123842,UniProt,G4NGT7,GenBank,EHA47447,,,70-15,Nst2 (MGG_04030),chromosome 6,,,,,PHI:123841,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,nucleotide sugar transporters,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl; Congo red; SDS; calcofluor white (CFW); H2O2; sorbitol; arabinose; fructose; galactose; glucose; sucrose; xylose; maltose,NaCl: CHEBI:26710; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; arabinose: CHEBI:22599; fructose: CHEBI:28757; galactose: CHEBI:28260; glucose: CHEBI:17234; sucrose: CHEBI:17992; xylose: CHEBI:18222; maltose: CHEBI:17306,,,,,gene deletion: full,,,NN,36775579,PubMed,10.1111/mpp.13304,Mol Plant Pathol. 2023 Apr;24(4):374-390,chenxiaolin@mail.hzau.edu.cn,"NSTs played important roles in cell wall integrity, were involved in asexual development, and were required for full virulence.",D Chen 2023,2023,2 genes,Chen-2023-Two nucleotide sugar transporters ar,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21427,PHI:123843,UniProt,C9Z451,GenBank,CBG72800,,,87-22,cebEFG1,,,,,,,1930,Streptomyces scabiei,680198,87-22,scab,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,seedling,CebEFG proteins,,,signaling pathway,reduced virulence,,,,,,,,reduced,,,,,,,,,gene deletion: full,,,NN,36829511,PubMed,10.3390/biology12020234,Biology (Basel). 2023 Feb 1;12(2):234,ifrancis@csub.edu,Deletion of cebEFG1 reduced virulence and thaxtomin production.,I M Francis 2023,2023,3 genes,Francis-2023-Role of Alternative Elicitor Tran,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21428,PHI:123844,UniProt,C9ZEJ9,GenBank,CBG67458,,,87-22,cebEFG2,,,,,,,1930,Streptomyces scabiei,680198,87-22,scab,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,seedling,CebEFG proteins,,,signaling pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36829511,PubMed,10.3390/biology12020234,Biology (Basel). 2023 Feb 1;12(2):234,ifrancis@csub.edu,Deletion of cebEFG2 reduced virulence and thaxtomin production.,I M Francis 2023,2023,3 genes,Francis-2023-Role of Alternative Elicitor Tran,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21429,PHI:123843,UniProt,C9Z451,GenBank,CBG72800,,,87-22,cebEFG1,,,,,,PHI:123844,1930,Streptomyces scabiei,680198,87-22,scab,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,seedling,CebEFG proteins,,,signaling pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36829511,PubMed,10.3390/biology12020234,Biology (Basel). 2023 Feb 1;12(2):234,ifrancis@csub.edu,Deletion of cebEFG1-2 reduced virulence and thaxtomin production.,I M Francis 2023,2023,3 genes,Francis-2023-Role of Alternative Elicitor Tran,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21430,PHI:123844,UniProt,C9ZEJ9,GenBank,CBG67458,,,87-22,cebEFG2,,,,,,PHI:123843,1930,Streptomyces scabiei,680198,87-22,scab,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,seedling,CebEFG proteins,,,signaling pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36829511,PubMed,10.3390/biology12020234,Biology (Basel). 2023 Feb 1;12(2):234,ifrancis@csub.edu,Deletion of cebEFG1-2 reduced virulence and thaxtomin production.,I M Francis 2023,2023,3 genes,Francis-2023-Role of Alternative Elicitor Tran,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21431,PHI:123845,UniProt,C9ZB05,GenBank,CBG74696,,,87-22,pitE,,,,,,,1930,Streptomyces scabiei,680198,87-22,scab,eudicots,3726,Raphanus sativus (related: radish),var. niger (Chinese radish),,,seedling,ABC-type transporter,,,signaling pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36829511,PubMed,10.3390/biology12020234,Biology (Basel). 2023 Feb 1;12(2):234,ifrancis@csub.edu,Deletion of pitE had no impact on virulence and thaxtomin production.,I M Francis 2023,2023,3 genes,Francis-2023-Role of Alternative Elicitor Tran,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21432,PHI:123846,UniProt,J9VJI7,GenBank,AFR92779,,,H99,Ysp2 (CNAG_00650),chromosome 1,,,,,,5207,Cryptococcus neoformans,,KN99α,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,retrograde sterol transporter,,,,loss of pathogenicity,,,,,,,,reduced,,no,SDS; amphicillin,ampicillin: CHEBI:28971; sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,36824733,PubMed,10.1101/2023.02.17.528979,bioRxiv. 2023 Feb 17;2023.02.17.528979,doering@wustl.edu,Mice infected with ysp2Δ showed no signs of illness and were only sacrificed when the experiment was terminated at day 80.,H L Chay 2023,2023,1 gene,Choy-2023-Ergosterol distribution controls sur,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21433,PHI:123847,UniProt,L2G915,GenBank,KAF4482309,,,Nara gc5,Vps29,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,vacuolar protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,SDS,sodium dodecyl sulfate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,36012823,PubMed,10.3390/jof8080835,J Fungi (Basel). 2022 Aug 10;8(8):835,t20061078@csuft.edu.cn,"CfVPS29 gene deletion is involved in growth, conidiation,pathogenicity and the response to cell wall stress",S Li 2022,2022,1 gene,Li-2022-The Retromer Subunit CfVps29 Is Involv,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21434,PHI:123848,UniProt,A8WDI5,GenBank,ABW86844,,,VIB283,rpoS,,,,,,,663,Vibrio alginolyticus,,ND-01,vibriosis,bony fishes,7955,Danio rerio (related: zebrafish),Tübingen,,,,RNA polymerase sigma factor RpoS,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,30811044,PubMed,10.1111/jfd.12972,J Fish Dis. 2019 May;42(5):703-712,yanqp@jmu.edu.cn,Zebrafish injected with rpoS-RNAi strain started to die since day 6 and reached 15% death ratio by day 6,L Huang 2019,2019,1 gene,Huang-2019-The role of rpoS in the regulation,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21435,PHI:123849,UniProt,B7UUJ7,GenBank,CAR48305,,,,toxR,,,,,,,663,Vibrio alginolyticus,,HY9901,vibriosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,,transmembrane regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,29151649,PubMed,10.1007/s12088-017-0685-x,Indian J Microbiol. 2017 Dec;57(4):477-484,shuanghucai@gmail.com,"No significant difference in the growth ability, swarming motility, activity of extracellular protease and the virulence by injection (the value of LD50) between the wild-type and the toxR mutant.",S Cai 2017,2017,1 gene,Cai-2017-Role of the toxR Gene from Fish Patho,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21436,PHI:123850,,no data found,,,,,,SsrA (AAW18_RS21575),,,,,,,339,Xanthomonas campestris,,pv. campestris strain Xc17,black rot,eudicots,3712,Brassica oleracea (no common name found),,,,leaf,small RNA,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,36750175,PubMed,10.1093/femsle/fnad009,FEMS Microbiol Lett. 2023 Jan 17;370:fnad009,ymhsiao@ctust.edu.tw,Lesion length provoked by ssrA mutant were significantly less than that provoked by the wild-type strain.,H-H Lo 2023,2023,2 genes,Lo-2023-SsrA and SmpB have multifaceted physio,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21437,PHI:123851,UniProt,Q8PAL7,,,,,,SmpB (AAW18_RS07500),,,,,,,339,Xanthomonas campestris,,pv. campestris strain Xc17,black rot,eudicots,3712,Brassica oleracea (no common name found),,,,leaf,SsrA-specific binding protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,36750175,PubMed,10.1093/femsle/fnad009,FEMS Microbiol Lett. 2023 Jan 17;370:fnad009,ymhsiao@ctust.edu.tw,Lesion length provoked by smpB mutant were significantly less than that provoked by the wild-type strain.,H-H Lo 2023,2023,2 genes,Lo-2023-SsrA and SmpB have multifaceted physio,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21438,PHI:123852,UniProt,B0Y4A7,GenBank,EDP51698,,,A1163,Rtt109 (AFUB_057090),,,,,,,746128,Aspergillus fumigatus,,A1160,invasive aspergillosis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,histone acetyltransferase,,,,reduced virulence,,,,,,reduced,,reduced,,no,methyl methanesulfonate; camptothecin; hydroxyurea,hydroxyurea: CHEBI:44423; methyl methanesulfonate: CHEBI:25255; camptothecin: CHEBI:27656,,,,,gene deletion: full; gene complementation,,,NN,33300219,PubMed,10.1111/mmi.14665,Mol Microbiol. 2021 Jun;115(6):1191-1206,linglu@njnu.edu.cn,"Deletion of Afrtt109 leads to severe defects in vegetative growth, conidiation, and causes reduced virulence in the Galleria mellonella model",Y Zhang 2020,2020,1 gene,Zhang-2020-The fungal-specific histone acetylt,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21439,PHI:123853,UniProt,A0A7S6PSA0,GenBank,QOU09079,,,YS1206,toxR,,,,,,,669,Vibrio harveyi,,345,luminous vibriosis,bony fishes,1074816,Epinephelus fuscoguttatus x Epinephelus lanceolatus (related: hybrid giant tiger grouper),,,,spleen; liver,membrane-bound regulatory protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,34822732,PubMed,10.1111/lam.13606,Lett Appl Microbiol. 2022 Feb;74(2):288-299,youlusu@zhku.edu.cn,"No significant differences in the growth ability, motility, virulence by intraperitoneal injection and the ability of V. harveyi to colonize the spleen and liver tissues of the pearl gentian grouper between the wild-type (WT) and the toxR mutant.",Y Zhang 2021,2021,1 gene,Zhang-2021-ToxR modulates biofilm formation in,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21440,PHI:123854,UniProt,D0VFJ6,GenBank,ACY41042,,,ZJ51,vscC,,,,,,,663,Vibrio alginolyticus,,Zjo5,vibriosis,bivalves,298176,Crassostrea hongkongensis (related: Hong King oyster),,,,,type III secretion system,,,apoptotic pathway,reduced virulence,,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,34621277,PubMed,10.3389/fimmu.2021.746017,Front Immunol. 2021 Sep 21;12:746017,yzhang@scsio.ac.cn,"Knocking out the vscC encoding gene, a core component of type III secretion system (T3SS), led to starkly reduced apoptotic rates in hemocyte hosts compared to the V. alginolyticusWT control.",F Mao 2021,2021,1 gene,Mao-2021-Virulence of Vibrio alginolyticus Acc,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21441,PHI:123855,UniProt,A0A8G2M7P3,GenBank,SUK15815,,,NCTC7972,cls1,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,cardiolipin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36778227,PubMed,10.1101/2023.02.01.526740,bioRxiv. 2023 Feb 2;2023.02.01.526740,shaun.brinsmade@georgetown.edu,The mice infected with WT or the cls1 mutant exhibited 95% and 90% mortality.,W-S Yeo 2023,2023,2 genes,Yeo-2023-Regulation of Bacterial Two-Component,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21442,PHI:123856,UniProt,A0A380EH96,GenBank,SUL35001,,,NCTC7972,cls2,,,,,,,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,cardiolipin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36778227,PubMed,10.1101/2023.02.01.526740,bioRxiv. 2023 Feb 2;2023.02.01.526740,shaun.brinsmade@georgetown.edu,Mice infected with cls2 mutant exhibited only 50% mortality compared to wild type exhibited 95% mortality.,W-S Yeo 2023,2023,2 genes,Yeo-2023-Regulation of Bacterial Two-Component,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21443,PHI:123855,UniProt,A0A8G2M7P3,GenBank,SUK15815,,,NCTC7972,cls1,,,,,,PHI:123856,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,cardiolipin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36778227,PubMed,10.1101/2023.02.01.526740,bioRxiv. 2023 Feb 2;2023.02.01.526740,shaun.brinsmade@georgetown.edu,Mice infected witht cls1 and cls2 double mutant exhibited 40% mortality compared to wild type exhibited 95% mortality.,W-S Yeo 2023,2023,2 genes,Yeo-2023-Regulation of Bacterial Two-Component,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21444,PHI:123856,UniProt,A0A380EH96,GenBank,SUL35001,,,NCTC7972,cls2,,,,,,PHI:123855,1280,Staphylococcus aureus,561307,RN4220,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,,cardiolipin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36778227,PubMed,10.1101/2023.02.01.526740,bioRxiv. 2023 Feb 2;2023.02.01.526740,shaun.brinsmade@georgetown.edu,Mice infected witht cls1 and cls2 double mutant exhibited 40% mortality compared to wild type exhibited 95% mortality.,W-S Yeo 2023,2023,2 genes,Yeo-2023-Regulation of Bacterial Two-Component,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21445,PHI:123857,,no data found,,,,,,hutZ,,,,,,,1263550,Edwardsiella piscicida,,TX01,gastroenteritis,bony fishes,8255,Paralichthys olivaceus (related: japanese flounder),,,,blood; liver; kidney; spleen,haem utilization protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,31578154,PubMed,10.1186/s13567-019-0693-4,Vet Res. 2019 Oct 2;50(1):76,Gongcg2005@163.com,Pathogenicity analysis showed that inactivation of hutZ Ep significantly impaired the ability of E. piscicida to invade and reproduce in host cells and to infect host tissue,Y-J Shi 2019,2019,1 gene,Shi-2019-HutZ is required for biofilm formatio,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21446,PHI:123858,UniProt,A0A7J6JLI2,GenBank,KAF4490823,,,Nara gc5,snt2,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaf,E3 ubiquitin-protein ligase,,,signaling pathway,reduced virulence,,,,,,,,reduced,,no,H2O2; DTT,H2O2: CHEBI:16240; dithiothreitol: CHEBI:42170,,,,,gene deletion: full; gene complementation,,,NN,36135699,PubMed,10.3390/jof8090974,J Fungi (Basel). 2022 Sep 18;8(9):974,csuftzsp@163.com,CfSnt2 is involved in pathogenicity in C. fructicola partially due to its roles in the formation of functional appressoria.,Y Guo 2022,2022,1 gene,Guo-2022-The CfSnt2-Dependent Deacetylation of,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21447,PHI:123859,UniProt,Q63WT5,GenBank,CAH34798,,,K96243,QseB (Q63WT5),chromosome 1,,,,,PHI:123860,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A.1,,,macrophage,response regulator protein,,,,reduced virulence,,,,,,,,,,no,kanamycin,kanamycin: CHEBI:6104,,,,,gene deletion: full; gene complementation,,,NN,36821630,PubMed,10.1371/journal.pone.0282098,PLoS One. 2023 Feb 23;18(2):e0282098,jo.stevens@roslin.ed.ac.uk,"At 4, 6, 8 and 24 h post-infection the numbers of intracellular ΔqseB mutant were significantly reduced compared to the wild-type strain.",C Meethai 2023,2023,2 genes,Meethai-2023-Analysis of the role of the QseBC,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21448,PHI:123860,UniProt,Q63WT4,GenBank,CAH34799,,,K96243,QseC (Q63WT4),chromosome 1,,,,,PHI:123859,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),J774A.1,,,macrophage,histidine kinase,,,,reduced virulence,,,,,,,,,,no,kanamycin,kanamycin: CHEBI:6104,,,,,gene deletion: full; gene complementation,,,NN,36821630,PubMed,10.1371/journal.pone.0282098,PLoS One. 2023 Feb 23;18(2):e0282098,jo.stevens@roslin.ed.ac.uk,"At 4, 6, 8 and 24 h post-infection the numbers of intracellular ΔqseC mutant were significantly reduced compared to the wild-type strain.",C Meethai 2023,2023,2 genes,Meethai-2023-Analysis of the role of the QseBC,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21449,PHI:123861,UniProt,G4N560,GenBank,EHA52118,,,70-15,PMO9A (MGG_06069),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,putative polysaccharide monooxygenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36791100,PubMed,10.1073/pnas.2215426120,Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2215426120,marletta@berkeley.edu,"The deletion of MoPMO9A results in significantly reduced pathogenicity of the rice blast fungus M. oryzae, and the pathogenicity was rescued by reintroducing MoPMO9A into the Δpmo9a mutant.",A Martinez 2023,2023,1 gene,Martinez-D'Alto-2023-Characterization of a uni,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21450,PHI:123862,,no data found,,,,,,FTL1678 (LdcA),,,,,,,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,lung; liver; spleen,"L,D-carboxypeptidase A",,,,loss of pathogenicity,,,,,,,,increased,,no,CuCl2; H2O2; NaCl,NaCl: CHEBI:26710; H2O2: CHEBI:16240; CuCl2: CHEBI:49553,,,,,gene deletion: full; gene complementation,,,NN,33469978,PubMed,10.1111/mmi.14685,Mol Microbiol. 2021 Jun;115(6):1357-1378,Jason.Huntley@UToledo.edu,"ΔFTL1678 was completely attenuated (100% survival through day 21 postinfection), resulting that FTL1678 is required for F. tularensis virulence.",B Zellner 2021,2021,2 genes,"Zellner-2021-A Francisella tularensis L,D-carb",BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21451,PHI:123863,,no data found,,,,,,FTL1678 (LdcA),,,,,,,263,Francisella tularensis,,Schu S4,tularemia,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,,"L,D-carboxypeptidase A",,,,reduced virulence,,,,,,,,increased,,no,CuCl2; H2O2; NaCl,NaCl: CHEBI:26710; H2O2: CHEBI:16240; CuCl2: CHEBI:49553,,,,,gene deletion: full; gene complementation,,,NN,33469978,PubMed,10.1111/mmi.14685,Mol Microbiol. 2021 Jun;115(6):1357-1378,Jason.Huntley@UToledo.edu,"Mice intranasally immunized with either 105, 107, or 109 CFU of ΔFTL1678 survived through day 28 postinfection, with no signs of clinical disease; On day 51, mice were intranasally challenged with 120 CFU (6 × the LD50) of SchuS4 and the health status of each immunization group was monitored for 26 days post-challengeand shows reduced virulence.",B Zellner 2021,2021,2 genes,"Zellner-2021-A Francisella tularensis L,D-carb",BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21452,PHI:123864,UniProt,D0ZGW2,GenBank,ACY86283,,,EIB202,Usp13 (WP_012850246.1),,,,,,,1263550,Edwardsiella piscicida,,TX01,gastroenteritis,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,liver; kidney; spleen,universal stress proteins,,,,reduced virulence,,,,,,,,reduced,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,31654767,PubMed,10.1016/j.fsi.2019.10.035,Fish Shellfish Immunol. 2019 Dec;95:248-258,guangyan0508@163.com,"The survival rate of TX01Δusp13-infected fish was 75.0%, which was significantly higher than that of TX01-infected fish (15.0%).",Q-J Fang 2019,2019,1 gene,Fang-2019-Universal stress proteins contribute,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21453,PHI:123865,UniProt,Q9ZHG7,GenBank,ASZ01578,,,874391,Sht,,,,,,,1311,Streptococcus agalactiae,,874391,neonatal pneumonia; neonatal meningitis; bovine mastitis; meningoencephalitis (fish),rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; spleen; heart; blood,streptococcal histidine triad protein,,,synthesis pathway for the GBS ornithine rhamnolipid hemolysin,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36747074,PubMed,10.1038/s41598-023-28117-x,Sci Rep. 2023 Feb 6;13(1):2137,g.ulett@griffith.edu.au,"Significantly higher numbers of WT GBS recovered from the blood, heart, lungs and spleen of mice compared to the Δsht mutant.",M J Sullivan 2023,2023,1 gene,Sullivan-2023-Dual RNA sequencing of group B S,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21454,PHI:123865,UniProt,Q9ZHG7,GenBank,ASZ01578,,,874391,Sht,,,,,,,1311,Streptococcus agalactiae,,874391,neonatal pneumonia; neonatal meningitis; bovine mastitis; meningoencephalitis (fish),rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain; bladder,streptococcal histidine triad protein,,,synthesis pathway for the GBS ornithine rhamnolipid hemolysin,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36747074,PubMed,10.1038/s41598-023-28117-x,Sci Rep. 2023 Feb 6;13(1):2137,g.ulett@griffith.edu.au,No significant difference between the numbers of WT GBS and Δsht mutant for the bladder and brain.,M J Sullivan 2023,2023,1 gene,Sullivan-2023-Dual RNA sequencing of group B S,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21455,PHI:123866,UniProt,L2GIQ8,GenBank,KAF4483641,,,Nara gc5,MK1 (CGGC5_15219),,,,,,,690256,Colletotrichum fructicola,,NC40,anthracnose,eudicots,23211,Pyrus communis (related: Pear),cv. Cuiguan; cv. Huangjin,,,fruit; leaf,MAPK gene,,,MAP kinase pathway,reduced virulence,,,yes,,smaller lesions,increased,reduced,reduced; defective,reduced,no,,,,,,,gene deletion: full; gene complementation,,,NN,35050017,PubMed,10.3390/jof8010077,J Fungi (Basel). 2022 Jan 14;8(1):77. doi: 10.3390/jof8010077,20010010@jaas.ac.cn,The ability of the Cfmk1 mutants to infect pear leaves and fruit was severely reduced.,C Li 2022,2022,1 gene,Li-2022-The CfMK1 Gene Regulates Reproduction,BATCH_120A,2023-03-01,MC,,,,,,,,,,,,,
,,Record 21456,PHI:123867,UniProt,A0A7R7V613,GenBank,BCR35100,,,NUF806,NAL (LC602499),,,,,,,1263550,Edwardsiella piscicida,,FPC498,gastroenteritis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,N-acetylneuraminate lyase,,,sialic acid catabolism pathway,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36755285,PubMed,10.1186/s12915-023-01513-5,BMC Biol. 2023 Feb 8;21(1):29. doi: 10.1186/s12915-023-01513-5,shiozaki@fish.kagoshima-u.ac.jp,"NAL-overexpressing strain induced lower fish survival (55.0%) compared to mock (75.0%, p<0.05).",L Kunz 2023,2023,2 genes,Vo-2022-Enhancement of Edwardsiella piscicida,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21457,PHI:123868,UniProt,A0A7R7V639,GenBank,BCR35099,,,NUF806,DHDPS (LC602498),,,,,,,1263550,Edwardsiella piscicida,,FPC498,gastroenteritis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,dihydrodipicolinate synthase,,,sialic acid catabolism pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36755285,PubMed,10.1186/s12915-023-01513-5,BMC Biol. 2023 Feb 8;21(1):29. doi: 10.1186/s12915-023-01513-5,shiozaki@fish.kagoshima-u.ac.jp,"Survival in DHDPS-infected zebrafish larvae was similar to that in mock (71.7%, p>0.05).",L Kunz 2023,2023,2 genes,Vo-2022-Enhancement of Edwardsiella piscicida,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21458,PHI:123869,UniProt,Q8P9S2,GenBank,AAM41066,,,ATCC 33913,sglT,,,,,,,339,Xanthomonas campestris,,pv. campestris strain 8008,black rot,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,,glucose transporter gene,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36762904,PubMed,10.1111/mpp.13302,Mol Plant Pathol. 2023 Apr;24(4):359-373. doi: 10.1111/mpp.13302. Epub 2023 Feb 10,jiayt@im.ac.cn,Deletion of the bacterial glucose transporter gene sglT impaired pathogen virulence and pip expression.,S Zhang 2023,2023,1 gene,Zhang-2023-Phytopathogenic bacteria utilize ho,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21459,PHI:123870,,no data found,GenBank,XP_040777266,,,EP155,Cop23,unknown,,,,,,5116,Cryphonectria parasitica,660469,EP155/2,blight (chestnut),eudicots,21020,Castanea sativa (related: chestnut),,,,bark,co-chaperone p23 gene,,,,reduced virulence,,,,,smaller necrotic area,reduced,,reduced; defective,,no,amphotericin B; ketoconazole; geldanamycin; Congo red; calcofluor white; sodium dodecyl sulphate (SDS),amphotericin B: CHEBI:2682; ketoconazole: CHEBI:48336; geldanamycin: CHEBI:5292; Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,36762926,PubMed,10.1111/mpp.13308,Mol Plant Pathol. 2023 Feb 10. doi: 10.1111/mpp.13308. Online ahead of print,dhkim@jbnu.ac.kr,Virulence of the CpCop23-null mutant was significantly reduced based on the smaller size of the necrotic area induced on excised bark compared to that induced by the wild type EP155/2.,Y H Ko 2023,2023,2 genes,Ko-2023-Hypoviral-regulated HSP90 co-chaperone,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21460,PHI:123871,UniProt,A0A6M4FAR2,GenBank,KAE9567608,,,CGMCC3.17371,EC92 (MN604401),,,,,,,690256,Colletotrichum fructicola,,1104-7,anthracnose,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf; fruit,effector protein,,,,effector (plant avirulence determinant),,,,,smaller necrotic lesions,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,32512647,PubMed,10.1111/mpp.12940,Mol Plant Pathol. 2020 Jul;21(7):936-950. doi: 10.1111/mpp.12940. Epub 2020 Apr 22,rongzh@nwsuaf.edu.cn,"Gene deletion mutant was not affected in vegetative growth, appressorium formationbut the mutant was significantly reduced in virulence toward apple leaves and fruits.",S Shang 2020,2020,1 gene,Shang-2020-A novel effector CfEC92 of Colletot,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21461,PHI:123872,,no data found,,,,,,YoeB (ETAE_RS17330),,,,,,,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,liver; kidney; spleen; blood,type II toxin system,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full,,,NN,33732226,PubMed,10.3389/fmicb.2021.646299,Front Microbiol. 2021 Mar 1;12:646299. doi: 10.3389/fmicb.2021.646299. eCollection 2021,sdmlzw@126.com,The survival rate of TX01- and TX01ΔyoeB-infected fish was 29 and 20%.,D Ma 2021,2021,2 genes,Ma-2021-Edwardsiella piscicida YefM-YoeB_ A Ty,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21462,PHI:123872,,no data found,,,,,,YoeB (ETAE_RS17330),,,,,,PHI:123873,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,liver; kidney; spleen; blood,type II toxin system,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,33732226,PubMed,10.3389/fmicb.2021.646299,Front Microbiol. 2021 Mar 1;12:646299. doi: 10.3389/fmicb.2021.646299. eCollection 2021,sdmlzw@126.com,"The deletion of yefM-yoeB enhanced the bacterial ability of high temperature tolerance, biofilm formation amd shows 0% survival rate.",D Ma 2021,2021,2 genes,Ma-2021-Edwardsiella piscicida YefM-YoeB_ A Ty,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21463,PHI:123873,,no data found,,,,,,YefM (ETAE_RS07650),,,,,,PHI:123872,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,liver; kidney; spleen; blood,type II antitoxin system,,,,increased virulence (hypervirulence),,,,,,,,,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,33732226,PubMed,10.3389/fmicb.2021.646299,Front Microbiol. 2021 Mar 1;12:646299. doi: 10.3389/fmicb.2021.646299. eCollection 2021,sdmlzw@126.com,"The deletion of yefM-yoeB enhanced the bacterial ability of high temperature tolerance, biofilm formation amd shows 0% survival rate.",D Ma 2021,2021,2 genes,Ma-2021-Edwardsiella piscicida YefM-YoeB_ A Ty,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21464,PHI:123874,UniProt,B0Y9W4,GenBank,EDP48807,,,A1163,ZfpA (AFUB_082490),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,reduced virulence,,,,,,,,wild type,,no,calcofluor white (CFW); H2O2; sorbitol; voriconazole; caspofungin; micafungin,"calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol CHEBI,  voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520",,,,,gene deletion: full,,,NN,36747761,PubMed,10.1101/2023.01.25.525624,bioRxiv. 2023 Jan 26:2023.01.25.525624. doi: 10.1101/2023.01.25.525624. Preprint,npkeller@wisc.edu,Virulence of ΔzfpA was attenuated in wild-type control larvae (mpx:rac2wt).,T J Schoen 2023,2023,1 gene,Schoen-2023-Aspergillus fumigatus transcriptio,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21465,PHI:123874,UniProt,B0Y9W4,GenBank,EDP48807,,,A1163,ZfpA (AFUB_082490),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,calcofluor white (CFW); H2O2; sorbitol; voriconazole; caspofungin; micafungin,"calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol CHEBI,  voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520",,,,,altered gene expression / gene regulation: overexpression,,,NN,36747761,PubMed,10.1101/2023.01.25.525624,bioRxiv. 2023 Jan 26:2023.01.25.525624. doi: 10.1101/2023.01.25.525624. Preprint,npkeller@wisc.edu,Virulence of OE::zfpA was similar to WT CEA10 control larvae (mpx:rac2wt).,T J Schoen 2023,2023,1 gene,Schoen-2023-Aspergillus fumigatus transcriptio,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21466,PHI:123874,UniProt,B0Y9W4,GenBank,EDP48807,,,A1163,ZfpA (AFUB_082490),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,calcofluor white (CFW); H2O2; sorbitol; voriconazole; caspofungin; micafungin,calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520,,,,,gene deletion: full,,,NN,36747761,PubMed,10.1101/2023.01.25.525624,bioRxiv. 2023 Jan 26:2023.01.25.525624. doi: 10.1101/2023.01.25.525624. Preprint,npkeller@wisc.edu,"In neutrophil-defective Rac2D57N larvae, ΔzfpA had similar virulence compared to WT CEA10.",T J Schoen 2023,2023,1 gene,Schoen-2023-Aspergillus fumigatus transcriptio,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21467,PHI:123874,UniProt,B0Y9W4,GenBank,EDP48807,,,A1163,ZfpA (AFUB_082490),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,calcofluor white (CFW); H2O2; sorbitol; voriconazole; caspofungin; micafungin,"calcofluor white (CFW): CHEBI:50011; H2O2: CHEBI:16240; D-sorbitol CHEBI,  voriconazole: CHEBI:10023; caspofungin: CHEBI:474180; micafungin: CHEBI:600520",,,,,altered gene expression / gene regulation: overexpression,,,NN,36747761,PubMed,10.1101/2023.01.25.525624,bioRxiv. 2023 Jan 26:2023.01.25.525624. doi: 10.1101/2023.01.25.525624. Preprint,npkeller@wisc.edu,"In neutrophil-defective Rac2D57N larvae, WT CEA10 97 remained less virulent than OE::zfpA.",T J Schoen 2023,2023,1 gene,Schoen-2023-Aspergillus fumigatus transcriptio,BATCH_120B,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21468,PHI:123875,UniProt,G4N0K3,GenBank,EHA53134,,,70-15,Mih1 (MGG_07734),chromosome 3,,,MoCdc28 (MGG_01362),UniProt: G4MZ20; GenBank: EHA54487,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,M-phase inducer phosphatase,,,cyclin dependent protein kinase,reduced virulence,,,yes,,tiny necrotic lesions,reduced,,reduced,,no,Congo red; calcofluor white; caffeine,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; caffeine: CHEBI:27732,,,,,gene deletion: full; gene complementation,,,NN,36998683,PubMed,10.3389/fpls.2023.1146915,Front Plant Sci. 2023 Mar 14;14:1146915. doi: 10.3389/fpls.2023.1146915. eCollection 2023,kandylemon@163.com,"The MoMih1 mutants significantly attenuated the virulence on host plant leaves, compared with KU80 and MoMih1c.",S Liu 2023,2023,3 genes,Liu-2023-MoMih1 is indispensable for asexual d,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21469,PHI:123875,UniProt,G4N0K3,GenBank,EHA53134,,,70-15,Mih1 (MGG_07734),chromosome 3,,,MoCdc28 (MGG_01362),UniProt: G4MZ20; GenBank: EHA54487,,318829,Magnaporthe oryzae,,Ku80,blast (rice),monocots,4513,Hordeum vulgare (related: Barley),cv. Golden Promise,,,leaf,M-phase inducer phosphatase,,,cyclin dependent protein kinase,reduced virulence,,,yes,,tiny necrotic lesions,reduced,,reduced,,no,Congo red; calcofluor white; caffeine,Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011; caffeine: CHEBI:27732,,,,,gene deletion: full; gene complementation,,,NN,36998683,PubMed,10.3389/fpls.2023.1146915,Front Plant Sci. 2023 Mar 14;14:1146915. doi: 10.3389/fpls.2023.1146915. eCollection 2023,kandylemon@163.com,"The MoMih1 mutants significantly attenuated the virulence on host plant leaves, compared with KU80 and MoMih1c.",S Liu 2023,2023,3 genes,Liu-2023-MoMih1 is indispensable for asexual d,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21470,PHI:123876,UniProt,G4NIX0,GenBank,EHA46186,,,70-15,Gin4 (MGG_02810),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: Barley),cv. Golden Promise,,,leaf,non-specific serine/threonine protein kinase,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36998683,PubMed,10.3389/fpls.2023.1146915,Front Plant Sci. 2023 Mar 14;14:1146915. doi: 10.3389/fpls.2023.1146915. eCollection 2023,kandylemon@163.com,The mutant (MoGin4) was dispensable for vegetative growth and pathogenicity.,S Liu 2023,2023,3 genes,Liu-2023-MoMih1 is indispensable for asexual d,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21471,PHI:123877,UniProt,G4MSL8,GenBank,EHA55439,,,70-15,Cyc2 (MGG_07065),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: Barley),cv. Golden Promise,,,leaf,G2/mitotic-specific cyclin-B,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36998683,PubMed,10.3389/fpls.2023.1146915,Front Plant Sci. 2023 Mar 14;14:1146915. doi: 10.3389/fpls.2023.1146915. eCollection 2023,kandylemon@163.com,The mutant (MoCyc2) was dispensable for vegetative growth and pathogenicity.,S Liu 2023,2023,3 genes,Liu-2023-MoMih1 is indispensable for asexual d,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21472,PHI:123878,UniProt,A1TM48,GenBank,ABM32036,,,AAC00-1,ntrC (Aave_1445),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Ruixin,,,seedling,nitrogen-regulating gene,,,,reduced virulence,,,,,,,,reduced,,no,KNO3; urea; ammonium sulfate,KNO3: CHEBI:63043; urea: CHEBI:16199; ammonium sulfate: CHEBI:62946,,,,,gene deletion: full; gene complementation,,,NN,36985340,PubMed,10.3390/microorganisms11030767,Microorganisms. 2023 Mar 16;11(3):767. doi: 10.3390/microorganisms11030767,yangyuwen@caas.cn,"The ntrC mutant strain exhibited significantly decreased virulence, in vitro growth, in vivo colonization ability and swimming motility.",D Liu 2023,2023,1 gene,Liu-2023-ntrC Contributes to Nitrogen Utilizat,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21473,PHI:123879,,no data found,GenBank,OQ425405,,,Foc4-PP1,PP1,,,,,,,5507,Fusarium oxysporum,1089451,f. sp. cubense TR4,wilt (banana),monocots,4641,Musa acuminata (related: dwarf banana),AAA group cv. Brazilian,,,root,α-pheromone precursor protein,,,,reduced virulence,,,,,,,,reduced,,no,H2O2; sorbitol; Congo red,H2O2: CHEBI:16240; D-sorbitol: CHEBI:17924; Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,36983533,PubMed,10.3390/jof9030365,J Fungi (Basel). 2023 Mar 16;9(3):365. doi: 10.3390/jof9030365,songhanda@zhku.edu.cn,Virulence of ΔFoc4-PP1 for banana plants was significantly reduced compared with that of the WT.,L Liu 2023,2023,1 gene,Liu-2023-alpha-Pheromone Precursor Protein Foc,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21474,PHI:123880,UniProt,G4MP53,GenBank,EHA56312,,,70-15,Tyr(MGG_14598),chromosome 1,,,,,,318829,Magnaporthe oryzae,1143189,Y34,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,tyrosinase,,,DHN melanin synthesis pathway,reduced virulence,,,,,smaller lesions,reduced,,,reduced,no,,,,,,,gene deletion: full,,,NN,36983479,PubMed,10.3390/jof9030311,J Fungi (Basel). 2023 Feb 28;9(3):311. doi: 10.3390/jof9030311,zhangsh89@syau.edu.cn,MoTyr deletion showed that conidiophore stalks and conidia formation was significantly reduced and affected both infection and pathogenesis stages.,X Fan 2023,2023,1 gene,Fan-2023-Contribution of the Tyrosinase (MoTyr,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21475,PHI:123880,UniProt,G4MP53,GenBank,EHA56312,,,70-15,Tyr(MGG_14598),chromosome 1,,,,,,318829,Magnaporthe oryzae,1143189,Y34,blast (rice),monocots,4513,Hordeum vulgare (related: Barley),,,,leaf,tyrosinase,,,DHN melanin synthesis pathway,reduced virulence,,,,,smaller lesions,reduced,,,reduced,no,,,,,,,gene deletion: full,,,NN,36983479,PubMed,10.3390/jof9030311,J Fungi (Basel). 2023 Feb 28;9(3):311. doi: 10.3390/jof9030311,zhangsh89@syau.edu.cn,MoTyr deletion showed that conidiophore stalks and conidia formation was significantly reduced and affected both infection and pathogenesis stages.,X Fan 2023,2023,1 gene,Fan-2023-Contribution of the Tyrosinase (MoTyr,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21476,PHI:123881,UniProt,A5CPF4,GenBank,CAN00952,,,NCPPB 382,pbpC,,,,,,,28447,Clavibacter michiganensis,,GS12102,bacterial canker,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,stem,penicillin-binding proteins,,,,increased virulence (hypervirulence),,,,,larger canker lesion,,,,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,36982399,PubMed,10.3390/ijms24065324,Int J Mol Sci. 2023 Mar 10;24(6):5324. doi: 10.3390/ijms24065324,luolaixin@cau.edu.cn,"The lesions caused by the GS12102-ΔpbpC mutant was much larger than those caused by the wild-type, pbpC-comp.",Y Li 2023,2023,2 genes,Li-2023-Deletion of pbpC Enhances Bacterial Pa,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21477,PHI:123881,UniProt,A5CPF4,GenBank,CAN00952,,,NCPPB 382,pbpC,,,,,,,28447,Clavibacter michiganensis,,GS12102,bacterial canker,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,stem,penicillin-binding proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36982399,PubMed,10.3390/ijms24065324,Int J Mol Sci. 2023 Mar 10;24(6):5324. doi: 10.3390/ijms24065324,luolaixin@cau.edu.cn,"The lesions caused by the GS12102-pbpC OE mutants was much similar to those caused by the wild-type, pbpC-comp.",Y Li 2023,2023,2 genes,Li-2023-Deletion of pbpC Enhances Bacterial Pa,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21478,PHI:123881,UniProt,A5CPF4,GenBank,CAN00952,,,NCPPB 382,pbpC,injection of exopolysaccharides (EPS),,,,,,28447,Clavibacter michiganensis,,GS12102,bacterial canker,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,stem,penicillin-binding proteins,,,,increased virulence (hypervirulence),,,,,larger canker lesion,,,,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,36982399,PubMed,10.3390/ijms24065324,Int J Mol Sci. 2023 Mar 10;24(6):5324. doi: 10.3390/ijms24065324,luolaixin@cau.edu.cn,"With the injection of EPS after C. michiganensis inoculation, the canker lesion sizes were significantly (p < 0.05) larger than those of the inoculated plants without EPS injections.",Y Li 2023,2023,2 genes,Li-2023-Deletion of pbpC Enhances Bacterial Pa,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21479,PHI:123881,UniProt,A5CPF4,GenBank,CAN00952,,,NCPPB 382,pbpC,injection of exopolysaccharides (EPS),,,,,,28447,Clavibacter michiganensis,,GS12102,bacterial canker,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,stem,penicillin-binding proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36982399,PubMed,10.3390/ijms24065324,Int J Mol Sci. 2023 Mar 10;24(6):5324. doi: 10.3390/ijms24065324,luolaixin@cau.edu.cn,"With the injection of EPS after C. michiganensis inoculation, the canker lesion sizes were significantly (p < 0.05) larger than those of the inoculated plants without EPS injections.",Y Li 2023,2023,2 genes,Li-2023-Deletion of pbpC Enhances Bacterial Pa,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21480,PHI:123882,UniProt,A5CPF4,GenBank,CAN00952,,,NCPPB 382,pbpC,,,,,,,28447,Clavibacter michiganensis,,BT0505,bacterial canker,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,stem,penicillin-binding proteins,,,,increased virulence (hypervirulence),,,,,larger canker lesion,,,,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,36982399,PubMed,10.3390/ijms24065324,Int J Mol Sci. 2023 Mar 10;24(6):5324. doi: 10.3390/ijms24065324,luolaixin@cau.edu.cn,"The lesions caused by the BT0505-ΔpbpC mutant was much larger than those caused by the wild-type, pbpC-comp.",Y Li 2023,2023,2 genes,Li-2023-Deletion of pbpC Enhances Bacterial Pa,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21481,PHI:123882,UniProt,A5CPF4,GenBank,CAN00952,,,NCPPB 382,pbpC,,,,,,,28447,Clavibacter michiganensis,,BT0505,bacterial canker,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,stem,penicillin-binding proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36982399,PubMed,10.3390/ijms24065324,Int J Mol Sci. 2023 Mar 10;24(6):5324. doi: 10.3390/ijms24065324,luolaixin@cau.edu.cn,"The lesions caused by the BT0505-pbpC OE mutants was much similar to those caused by the wild-type, pbpC-comp.",Y Li 2023,2023,2 genes,Li-2023-Deletion of pbpC Enhances Bacterial Pa,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21482,PHI:123882,UniProt,A5CPF4,GenBank,CAN00952,,,NCPPB 382,pbpC,injection of exopolysaccharides (EPS),injection of exopolysaccharides (EPS),,,,,28447,Clavibacter michiganensis,,BT0505,bacterial canker,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,stem,penicillin-binding proteins,,,,increased virulence (hypervirulence),,,,,larger canker lesion,,,,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,36982399,PubMed,10.3390/ijms24065324,Int J Mol Sci. 2023 Mar 10;24(6):5324. doi: 10.3390/ijms24065324,luolaixin@cau.edu.cn,"With the injection of EPS after C. michiganensis inoculation, the canker lesion sizes were significantly (p < 0.05) larger than those of the inoculated plants without EPS injections.",Y Li 2023,2023,2 genes,Li-2023-Deletion of pbpC Enhances Bacterial Pa,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21483,PHI:123882,UniProt,A5CPF4,GenBank,CAN00952,,,NCPPB 382,pbpC,injection of exopolysaccharides (EPS),injection of exopolysaccharides (EPS),,,,,28447,Clavibacter michiganensis,,BT0505,bacterial canker,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,stem,penicillin-binding proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36982399,PubMed,10.3390/ijms24065324,Int J Mol Sci. 2023 Mar 10;24(6):5324. doi: 10.3390/ijms24065324,luolaixin@cau.edu.cn,"With the injection of EPS after C. michiganensis inoculation, the canker lesion sizes were significantly (p < 0.05) larger than those of the inoculated plants without EPS injections.",Y Li 2023,2023,2 genes,Li-2023-Deletion of pbpC Enhances Bacterial Pa,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21484,PHI:123883,UniProt,G4MRT1,GenBank,EHA58296,,,70-15,HTR3,chromosome 1,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,effector protein,,,JA signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36977203,PubMed,10.1111/mpp.13326,Mol Plant Pathol. 2023 Mar 28. doi: 10.1111/mpp.13326. Online ahead of print,yonglee@snu.ac.kr,Lesion formation in ΔMohtr3 and the complementation line were indistinguishable from that of the wild type (WT).,S Lee 2023,2023,1 gene,Lee-2023-The nuclear effector MoHTR3 of Magnap,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21485,PHI:123883,UniProt,G4MRT1,GenBank,EHA58296,,,70-15,HTR3,chromosome 1,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nakdongbyeo,,,leaf,effector protein,,,JA signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36977203,PubMed,10.1111/mpp.13326,Mol Plant Pathol. 2023 Mar 28. doi: 10.1111/mpp.13326. Online ahead of print,yonglee@snu.ac.kr,Infection with MoHTR3ox strains was weaker and resulted in small disease lesions.,S Lee 2023,2023,1 gene,Lee-2023-The nuclear effector MoHTR3 of Magnap,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21486,PHI:123884,,no data found,,,,,,Tem1 (FGSG_17139),,,,Cdc10 (FGSG_06035); Cdc11 (FGSG_09421),,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Spring wheat,,,spikelet; coleoptile,small GTPase,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36928713,PubMed,10.1371/journal.ppat.1011255,PLoS Pathog. 2023 Mar 16;19(3):e1011255,zhw@mju.edu.cn,"ΔFgtem1 mutant shows slight reduction in the vegetative growth, conidia and virulence",P Miao 2023,2023,3 genes,Miao-2023-The mitotic exit mediated by small G,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21487,PHI:123885,UniProt,I1RBX2,,,,,,Bub2 (FGSG_01065),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Spring wheat,,,spike,cell cycle arrest protein,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,calcofluor white,calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,36928713,PubMed,10.1371/journal.ppat.1011255,PLoS Pathog. 2023 Mar 16;19(3):e1011255,zhw@mju.edu.cn,"PH-1 showed an average disease index of approximately 15.28, while the ΔFgbub2 mutant had less than 12.",P Miao 2023,2023,3 genes,Miao-2023-The mitotic exit mediated by small G,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21488,PHI:123886,UniProt,I1RQA1,,,,,,Bfa1(FGSG_06242),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Spring wheat,,,spike,cell cycle arrest protein,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,calcofluor white,calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,36928713,PubMed,10.1371/journal.ppat.1011255,PLoS Pathog. 2023 Mar 16;19(3):e1011255,zhw@mju.edu.cn,"PH-1 showed an average disease index of approximately 15.28, while the ΔFgbfa1 mutants had less than 12.",P Miao 2023,2023,3 genes,Miao-2023-The mitotic exit mediated by small G,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21489,PHI:123885,UniProt,I1RBX2,,,,,,Bub2 (FGSG_01065),,,,,,PHI:123886,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Spring wheat,,,spike,cell cycle arrest protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white,calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,36928713,PubMed,10.1371/journal.ppat.1011255,PLoS Pathog. 2023 Mar 16;19(3):e1011255,zhw@mju.edu.cn,"PH-1 showed an average disease index of approximately 15.28, while the ΔFgbub2 ΔFgbfa1 double mutant had less than 12.",P Miao 2023,2023,3 genes,Miao-2023-The mitotic exit mediated by small G,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21490,PHI:123886,UniProt,I1RQA1,,,,,,Bfa1(FGSG_06242),,,,,,PHI:123885,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Spring wheat,,,spike,cell cycle arrest protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,calcofluor white,calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,36928713,PubMed,10.1371/journal.ppat.1011255,PLoS Pathog. 2023 Mar 16;19(3):e1011255,zhw@mju.edu.cn,"PH-1 showed an average disease index of approximately 15.28, while the ΔFgbub2 ΔFgbfa1 double mutant had less than 12.",P Miao 2023,2023,3 genes,Miao-2023-The mitotic exit mediated by small G,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21491,PHI:123887,UniProt,Q5ABS1,GenBank,AOW30270,,,SC5314,QCR7,chromosome 6,,,,,,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cytochrome b-c1 complex subunit 7 gene,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36923588,PubMed,10.3389/fcimb.2023.1136698,Front Cell Infect Microbiol. 2023 Feb 27;13:1136698. doi: 10.3389/fcimb.2023.1136698. eCollection 2023,xthuang@ncu.edu.cn,The survival rate of the mice injected with the qcr7Δ/Δ mutant was much higher than that of those injected with the WT and QCR7 complement strain.,L Zeng 2023,2023,1 gene,Zeng-2023-QCR7 affects the virulence of Candid,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21492,PHI:123888,UniProt,E9ES99,GenBank,EFZ01616,,,ARSEF 23,WetA (EFZ01616),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,developmental regulatory protein wetA,,,,reduced virulence,,,,,,reduced,,wild type,,no,Congo red; H2O2; menadione; CFW; NaCl; sorbitol,Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,36916980,PubMed,10.1128/spectrum.00070-23,Microbiol Spectr. 2023 Mar 14;11(2):e0007023. doi: 10.1128/spectrum.00070-23. Online ahead of print,mgfeng@zju.edu.cn,LT50 of ΔwetA was prolonged to 21.9 (60.9) days via NCI and to 3.8 (60.1) days via CBI compared to wild type.,J G Zhang 2023,2023,2 genes,"Zhang-2023-Essential Role of WetA, but No Role",BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21493,PHI:123889,UniProt,E9F0R3,GenBank,EFY98723,,,ARSEF 23,VosA (EFY98723),,,,,,,568076,Metarhizium robertsii,1432499,ARSEF 2575,,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,velvety protein,,,,unaffected pathogenicity,,,,,,wild type,,wild type,,no,Congo red; H2O2; menadione; CFW; NaCl; sorbitol,Congo red: CHEBI:34653; H2O2: CHEBI:16240; menadione: CHEBI:28869; D-sorbitol: CHEBI:17924; NaCl: CHEBI:26710; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,36916980,PubMed,10.1128/spectrum.00070-23,Microbiol Spectr. 2023 Mar 14;11(2):e0007023. doi: 10.1128/spectrum.00070-23. Online ahead of print,mgfeng@zju.edu.cn,The ΔvosA mutant's LT50s was 11.9 (60.3) and 3.4 (60.2) days days via NCI and CBI which was similar to wild type.,J G Zhang 2023,2023,2 genes,"Zhang-2023-Essential Role of WetA, but No Role",BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21494,PHI:123890,UniProt,Q6A3P9,GenBank,CAE17672,,,D141,ureB (AFUA_1G04560),,,,,,,746128,Aspergillus fumigatus,1266464,CEA17,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung; liver,urease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36916906,PubMed,10.1128/spectrum.03508-22,Microbiol Spectr. 2023 Mar 14;11(2):e0350822. doi: 10.1128/spectrum.03508-22. Online ahead of print,dhscharf@zju.edu.cn.,The urease deficient mutant displays attenuated virulence,Z Xiong 2023,2023,1 gene,Xiong-2023-Urease of Aspergillus fumigatus Is,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21495,PHI:123891,UniProt,K3VDG8,GenBank,EKJ72092,,,CS3096,LaeB (XP_009259110.1),,,,,,,101028,Fusarium pseudograminearum,1028729,CS3096,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; stem,regulator,,,,reduced virulence,,,,,,reduced,,reduced,,no,Congo red; H2O2; NaCl; SDS,Congo red: CHEBI:34653; H2O2: CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full; gene complementation,,,NN,36909432,PubMed,10.3389/fpls.2023.1132507,Front Plant Sci. 2023 Feb 22;14:1132507. doi: 10.3389/fpls.2023.1132507. eCollection 2023,konglingxiao163@163.com,The virulence was decreased when the FpLaeB deletion mutant was inoculated onto the wheat stem base or head.,Y Wu 2023,2023,1 gene,Wu-2023-The global regulator FpLaeB is require,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21496,PHI:123892,UniProt,A0A4T0VYD8,GenBank,TIC97814,,,MAFF305635-RFP,atg8,,,,,,,80884,Colletotrichum higginsianum,759273,IMI349063,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,autophagy,,,autophagy pathway,unaffected pathogenicity,,,,,,,,reduced; defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36901806,PubMed,10.3390/ijms24054376,Int J Mol Sci. 2023 Feb 22;24(5):4376. doi: 10.3390/ijms24054376,exzhou@scau.edu.cn,The Chatg8Δ mutant hardly caused any necrotic lesions to the inoculated leaves at all time points whereas no disease lesions on Arabidopsis leaves inoculated with the WT was seen.,Y Zhu 2023,2023,2 genes,Zhu-2023-Dual Transcriptome Analysis Reveals T,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21497,PHI:123893,UniProt,A0A1B7Y5W1,GenBank,OBR07392,,,IMI 349063,thr1 (CH63R_08913),chromosome 6,,,,,,80884,Colletotrichum higginsianum,759273,IMI349063,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: Thale cress),ecotype Columbia-0,,,leaf,trihydroxynaphthalene reductase,,,melanin biosynthesis pathway,loss of pathogenicity,,,,,,,,reduced; defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36901806,PubMed,10.3390/ijms24054376,Int J Mol Sci. 2023 Feb 22;24(5):4376. doi: 10.3390/ijms24054376,exzhou@scau.edu.cn,The Chthr1Δ strain lost pathogenicity.,Y Zhu 2023,2023,2 genes,Zhu-2023-Dual Transcriptome Analysis Reveals T,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21498,PHI:123894,UniProt,G7SES6,GenBank,AER20303,,,D12,Cba (AER203031),,,,,,,1307,Streptococcus suis,,SS9-P10,meningitis; septicemia; arthritis; pneumonia (pig),rodents,10090,Mus musculus (related: house mouse),ICR,,,lung; spleen; liver; kidney,collagen-binding adhesive,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36896190,PubMed,10.3389/fcimb.2023.1027419,Front Cell Infect Microbiol. 2023 Feb 21;13:1027419. doi: 10.3389/fcimb.2023.1027419. eCollection 2023,xlyu999@126.com,"Knocking out the cba gene did not affect the growth characteristics of the strain, but it significantly reduced the ability of SS to form biofilms and attenuated virulence in a mouse infection model.",P Yang 2023,2023,1 gene,Yang-2023-Novel virulence factor Cba induces a,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21499,PHI:123895,UniProt,Q9RM76,GenBank,CAB58425,,,IS51,cdtA,,,,,,PHI:123896,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,clostridioides difficile binary toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36895287,PubMed,10.1093/ofid/ofad040,Open Forum Infect Dis. 2023 Jan 31;10(3):ofad040. doi: 10.1093/ofid/ofad040. eCollection 2023 Mar,wap3g@virginia.edu,Mice infected with either the ΔcdtAB strain did not show any signs of weight loss or significant disease.,M Simpson 2023,2023,2 genes,Simpson-2023-Clostridioides difficile Binary T,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21500,PHI:123896,UniProt,A8DS70,GenBank,ABS57477,,,CD196,cdtB,,,,,,PHI:123895,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum,clostridioides difficile binary toxin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36895287,PubMed,10.1093/ofid/ofad040,Open Forum Infect Dis. 2023 Jan 31;10(3):ofad040. doi: 10.1093/ofid/ofad040. eCollection 2023 Mar,wap3g@virginia.edu,Mice infected with either the ΔcdtAB strain did not show any signs of weight loss or significant disease.,M Simpson 2023,2023,2 genes,Simpson-2023-Clostridioides difficile Binary T,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21501,PHI:123895,UniProt,Q9RM76,GenBank,CAB58425,,,IS51,cdtA,,,,,,PHI:123896,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,cecum,clostridioides difficile binary toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36895287,PubMed,10.1093/ofid/ofad040,Open Forum Infect Dis. 2023 Jan 31;10(3):ofad040. doi: 10.1093/ofid/ofad040. eCollection 2023 Mar,wap3g@virginia.edu,Mice infected with either the ΔcdtAB strain shows redudced signs of weight loss or significant disease compared to CDTb+.,M Simpson 2023,2023,2 genes,Simpson-2023-Clostridioides difficile Binary T,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21502,PHI:123896,UniProt,A8DS70,GenBank,ABS57477,,,CD196,cdtB,,,,,,PHI:123895,1496,Clostridioides difficile,645463,R20291,pseudomembranous colitis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,cecum,clostridioides difficile binary toxin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36895287,PubMed,10.1093/ofid/ofad040,Open Forum Infect Dis. 2023 Jan 31;10(3):ofad040. doi: 10.1093/ofid/ofad040. eCollection 2023 Mar,wap3g@virginia.edu,Mice infected with either the ΔcdtAB strain shows redudced signs of weight loss or significant disease compared to CDTb+.,M Simpson 2023,2023,2 genes,Simpson-2023-Clostridioides difficile Binary T,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21503,PHI:123897,,no data found,,,,,,CRN17,,,,,,,143451,Plasmopara viticola,,,downy mildew (grape),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression,,,NN,36071584,PubMed,10.1111/mpp.13266,Mol Plant Pathol. 2022 Dec;23(12):1792-1806. doi: 10.1111/mpp.13266. Epub 2022 Sep 7,yan.xu@nwafu.edu.cn,PvCRN17 showed a virulent effect towards Nicotiana benthamiana.,G Xiang 2022,2022,1 gene,Xiang-2022-The cytosolic iron-sulphur cluster,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21504,PHI:123897,,no data found,,,,,,CRN17,,,,,,,143451,Plasmopara viticola,,,downy mildew (grape),eudicots,96939,Vitis riparia (related: riverbank grape),Liuba-8,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression,,,NN,36071584,PubMed,10.1111/mpp.13266,Mol Plant Pathol. 2022 Dec;23(12):1792-1806. doi: 10.1111/mpp.13266. Epub 2022 Sep 7,yan.xu@nwafu.edu.cn,PvCRN17 showed a virulent effect on grapevine plants.,G Xiang 2022,2022,1 gene,Xiang-2022-The cytosolic iron-sulphur cluster,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21505,PHI:123898,UniProt,A0A7U7JEC4,GenBank,CEJ17353,,,IPO1609,RipA5,,,,,,,305,Ralstonia solanacearum,,HA4-1,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,All plants with ΔRipA5 showed wilting symptoms.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21506,PHI:123899,,no data found,,,,,,RipBS,,,,,,,305,Ralstonia solanacearum,,HA4-1,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,All plants with ΔRipBS showed wilting symptoms.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21507,PHI:123900,,no data found,,,,,,Hyp6,,,,,,,305,Ralstonia solanacearum,,HA4-1,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,All plants with ΔHyp6 showed wilting symptoms.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21508,PHI:123901,UniProt,A0A224AJ79,GenBank,BBA13867,,,OE1-1,RipS6,,,,,,,305,Ralstonia solanacearum,,HA4-1,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,"RipS6 was mutated, the wilt symptom of ALB28-1 was the most severe.",M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21509,PHI:123902,UniProt,A0A7U7JF45,GenBank,CEJ17765,,,IPO1609,RipO1,,,,,,,305,Ralstonia solanacearum,,HA4-1,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,All plants with ΔRipO1 showed wilting symptoms.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21510,PHI:123899,,no data found,,,,,,RipBS,,,,,,,305,Ralstonia solanacearum,,HA4-1,bacterial wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. E-Potato 3,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,"E3, inoculated with HA4-1, HA4-1 ΔRipBS showed wilting symptoms with no significant difference.",M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21511,PHI:123901,UniProt,A0A224AJ79,GenBank,BBA13867,,,OE1-1,RipS6,,,,,,,305,Ralstonia solanacearum,,HA4-1,bacterial wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. E-Potato 3,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,"E3, inoculated with HA4-1, HA4-1 ΔRipS6 showed wilting symptoms with no significant difference.",M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21512,PHI:123902,UniProt,A0A7U7JEC4,GenBank,CEJ17353,,,IPO1609,RipA5,,,,,,,305,Ralstonia solanacearum,,HZAU091,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,HZAU091:: RipA5 significantly depressed the virulence at the early stage.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21513,PHI:123903,,no data found,,,,,,RipBS,,,,,,,305,Ralstonia solanacearum,,HZAU091,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,HZAU091::RipBS significantly reduced the virulence of HZAU091.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21514,PHI:123904,,no data found,,,,,,Hyp6,,,,,,,305,Ralstonia solanacearum,,HZAU091,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,A higher disease index was observed by HZAU091::Hyp6 than HZAU091.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21515,PHI:123905,UniProt,A0A224AJ79,GenBank,BBA13867,,,OE1-1,RipS6,,,,,,,305,Ralstonia solanacearum,,HZAU091,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,HZAU091::RipS6 significantly depressed the virulence at the early stage.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21516,PHI:123906,UniProt,A0A7U7JF45,GenBank,CEJ17765,,,IPO1609,RipO1,,,,,,,305,Ralstonia solanacearum,,HZAU091,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,HZAU091:: RipO1 significantly reduced the virulence at the late stage.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21517,PHI:123907,UniProt,A0A7U7JEC0,GenBank,CEJ17242,,,IPO1609,RipAO,,,,,,,305,Ralstonia solanacearum,,HZAU091,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,HZAU091::RipAO significantly depressed the virulence at the early stage.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21518,PHI:123908,,no data found,,,,,,RipH1,,,,,,,305,Ralstonia solanacearum,,HZAU091,bacterial wilt,eudicots,315333,Solanum albicans (no common name found),28-1,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36909411,PubMed,10.3389/fpls.2023.1075042,Front Plant Sci. 2023 Feb 23;14:1075042. doi: 10.3389/fpls.2023.1075042. eCollection 2023,wangbingsen@webmail.hzau.edu.cn,The development trend showed a trade-off with HZAU091 compared with HZAU091::RipH1.,M Huang 2023,2023,12 genes,Huang-2023-Comparative genomic analysis of Ral,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21519,PHI:123909,UniProt,G4MTS7,GenBank,EHA53916,,,70-15,dync1I2,chromosome 2,truncating the NLS located at close the N-terminal region of MoDync1I2,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cytoplasmic dynein1 intermediate-chain2,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36866040,PubMed,10.1016/j.isci.2023.106050,iScience. 2023 Feb 10;26(2):106050. doi: 10.1016/j.isci.2023.106050. eCollection 2023 Feb 17,zonghuaw@163.com,Infections assessment results of ΔModync1I2:MoDYNC1I2ΔNLS revealed a substantial reduction in the virulence of the MoDync1I2ΔNLS strains.,L Lin 2023,2023,1 gene,Lin-2023-Cytoplasmic dynein1 intermediate-chai,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21520,PHI:123909,UniProt,G4MTS7,GenBank,EHA53916,,,70-15,dync1I2,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,cytoplasmic dynein1 intermediate-chain2,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36866040,PubMed,10.1016/j.isci.2023.106050,iScience. 2023 Feb 10;26(2):106050. doi: 10.1016/j.isci.2023.106050. eCollection 2023 Feb 17,zonghuaw@163.com,ΔModync1I2 strains failed to induce blast lesions on intact and injured barley leaves.,L Lin 2023,2023,1 gene,Lin-2023-Cytoplasmic dynein1 intermediate-chai,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21521,PHI:123909,UniProt,G4MTS7,GenBank,EHA53916,,,70-15,dync1I2,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,cytoplasmic dynein1 intermediate-chain2,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36866040,PubMed,10.1016/j.isci.2023.106050,iScience. 2023 Feb 10;26(2):106050. doi: 10.1016/j.isci.2023.106050. eCollection 2023 Feb 17,zonghuaw@163.com,MoYNC1I2 OE substantially increased the virulence of the strains in both intact and injured leaves.,L Lin 2023,2023,1 gene,Lin-2023-Cytoplasmic dynein1 intermediate-chai,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21522,PHI:123909,UniProt,G4MTS7,GenBank,EHA53916,,,70-15,dync1I2,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cytoplasmic dynein1 intermediate-chain2,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36866040,PubMed,10.1016/j.isci.2023.106050,iScience. 2023 Feb 10;26(2):106050. doi: 10.1016/j.isci.2023.106050. eCollection 2023 Feb 17,zonghuaw@163.com,MoΔYNC1I2 OE substantially altered the virulence of the strains on leaves.,L Lin 2023,2023,1 gene,Lin-2023-Cytoplasmic dynein1 intermediate-chai,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21523,PHI:123909,UniProt,G4MTS7,GenBank,EHA53916,,,70-15,dync1I2,chromosome 2,transformation of His1-GFP into ΔModync1I2 strain,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,cytoplasmic dynein1 intermediate-chain2,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36866040,PubMed,10.1016/j.isci.2023.106050,iScience. 2023 Feb 10;26(2):106050. doi: 10.1016/j.isci.2023.106050. eCollection 2023 Feb 17,zonghuaw@163.com,They remain non-pathogenic against blast susceptible barley seedlings.,L Lin 2023,2023,1 gene,Lin-2023-Cytoplasmic dynein1 intermediate-chai,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21524,PHI:123909,UniProt,G4MTS7,GenBank,EHA53916,,,70-15,dync1I2,chromosome 2,transformation of His1-GFP into ΔModync1I2 strain,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cytoplasmic dynein1 intermediate-chain2,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36866040,PubMed,10.1016/j.isci.2023.106050,iScience. 2023 Feb 10;26(2):106050. doi: 10.1016/j.isci.2023.106050. eCollection 2023 Feb 17,zonghuaw@163.com,They remain non-pathogenic against blast susceptible barley seedlings.,L Lin 2023,2023,1 gene,Lin-2023-Cytoplasmic dynein1 intermediate-chai,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21525,PHI:123910,UniProt,A0A1D8PDC4,GenBank,AOW26135,,,SC5314,ATP1,chromosome 1,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,F1Fo-ATP synthase α subunit,,,cAMP-PKA pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36914568,PubMed,10.1080/21505594.2023.2190645,Virulence. 2023 Dec;14(1):2190645,tzhangh@jnu.edu.cn,"Survival rate of G. mellonella infected with atp1Δ/Δ was 100%, while that of WT was 16.6%.",S Li 2023,2023,1 gene,Li-2023-The F(1)F(o)-ATP synthase alpha subuni,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21526,PHI:123911,UniProt,Q8Y1X2,GenBank,CAD14095,,,GMI1000,RS_RS02830 (RSc0565),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,seedling,lipopolysaccharide heptosyltransferase II,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36912695,PubMed,10.1111/mpp.13321,,dehong@gxu.edu.cn,RS_RS02830 scarcely caused wilt symptoms in tomato plants.,H Zhang 2023,2023,5 genes,Zhang-2023-Tn-seq identifies Ralstonia solanac,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21527,PHI:123911,UniProt,Q8Y1X2,GenBank,CAD14095,,,GMI1000,RS_RS02830 (RSc0565),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,seedling,lipopolysaccharide heptosyltransferase II,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36912695,PubMed,10.1111/mpp.13321,,dehong@gxu.edu.cn,"In Salicylic acid treated tomato plants, ΔRS_RS02830 did not cause any wilt symptoms.",H Zhang 2023,2023,5 genes,Zhang-2023-Tn-seq identifies Ralstonia solanac,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21528,PHI:123912,UniProt,Q8Y1K2,GenBank,CAD14218,,,GMI1000,RS_RS03460 (RSc0688),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,seedling,glycosyltransferase family 2 protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36912695,PubMed,10.1111/mpp.13321,,dehong@gxu.edu.cn,The virulence of ΔRS_RS03460 in nontreated plants was significantly weaker than that of the wild-type strain GMI1000.,H Zhang 2023,2023,5 genes,Zhang-2023-Tn-seq identifies Ralstonia solanac,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21529,PHI:123912,UniProt,Q8Y1K2,GenBank,CAD14218,,,GMI1000,RS_RS03460 (RSc0688),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,seedling,glycosyltransferase family 2 protein,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36912695,PubMed,10.1111/mpp.13321,,dehong@gxu.edu.cn,"In Salicylic acid treated tomato plants, ΔRS_RS03460 did not cause any wilt symptoms.",H Zhang 2023,2023,5 genes,Zhang-2023-Tn-seq identifies Ralstonia solanac,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21530,PHI:123913,UniProt,Q8Y1K1,GenBank,CAD14219,,,GMI1000,RS_RS03465 (RSc0689),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,seedling,glycosyl transferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36912695,PubMed,10.1111/mpp.13321,,dehong@gxu.edu.cn,The virulence of ΔRS_RS03465 in nontreated plants was significantly weaker than that of the wild-type strain GMI1000.,H Zhang 2023,2023,5 genes,Zhang-2023-Tn-seq identifies Ralstonia solanac,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21531,PHI:123913,UniProt,Q8Y1K1,GenBank,CAD14219,,,GMI1000,RS_RS03465 (RSc0689),,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,seedling,glycosyl transferase,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36912695,PubMed,10.1111/mpp.13321,,dehong@gxu.edu.cn,"In Salicylic acid treated tomato plants, ΔRS_RS03465 did not cause any wilt symptoms.",H Zhang 2023,2023,5 genes,Zhang-2023-Tn-seq identifies Ralstonia solanac,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21532,PHI:123914,,no data found,,,,,,RS_RS11975,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,seedling,DUF3460 domain-containing protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36912695,PubMed,10.1111/mpp.13321,,dehong@gxu.edu.cn,No obvious control effect on the bacterial wilt caused by ΔRS_RS11975.,H Zhang 2023,2023,5 genes,Zhang-2023-Tn-seq identifies Ralstonia solanac,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21533,PHI:123914,,no data found,,,,,,RS_RS11975,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,seedling,DUF3460 domain-containing protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36912695,PubMed,10.1111/mpp.13321,,dehong@gxu.edu.cn,ΔRS_RS11975 caused more severe wilt symptoms in SAtreated plants than the wild-type strain GMI1000.,H Zhang 2023,2023,5 genes,Zhang-2023-Tn-seq identifies Ralstonia solanac,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21534,PHI:123915,,no data found,,,,,,RS_RS07760,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,seedling,hypothetical protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36912695,PubMed,10.1111/mpp.13321,,dehong@gxu.edu.cn,Virulence on tomato plants of the ΔRS_ RS07760 were similar to those of the wild-type strain GMI1000.,H Zhang 2023,2023,5 genes,Zhang-2023-Tn-seq identifies Ralstonia solanac,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21535,PHI:123915,,no data found,,,,,,RS_RS07760,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Zhongshu 4,,,seedling,hypothetical protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36912695,PubMed,10.1111/mpp.13321,,dehong@gxu.edu.cn,"The disease control efficiency of SA treatment on bacterial wilt caused by GMI1000 was 54.4% at 12 days postinoculation, but the control efficiency on bacterial wilt caused by ΔRS_RS07760 was reduced to 11.1%.",H Zhang 2023,2023,5 genes,Zhang-2023-Tn-seq identifies Ralstonia solanac,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21536,PHI:123916,UniProt,A0A2X7Q244,GenBank,SQJ62275,,,VREC0376,Hcp1,,,,,,,562,Escherichia coli,,W24,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,spleen; lung; small intestine; liver; kidney,hemolysin-coregulated protein 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36977062,PubMed,10.3390/toxins15030171,Toxins (Basel). 2023 Feb 22;15(3):171. doi: 10.3390/toxins15030171,aipengpengpiao@163.com,Mice infected with WT W24 developed a more serious systemic infection than those infected with W24Dhcp1,H Wang 2023,2023,1 gene,Wang-2023-Hemolysin Co-Regulatory Protein 1 En,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21537,PHI:123917,,no data found,,,,,,Pt13024,,,,,,,208348,Puccinia triticina,,race 13-5-72,leaf rust (wheat),monocots,4565,Triticum aestivum (related: bread wheat),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,36726676,PubMed,10.3389/fpls.2022.1098549,Front Plant Sci. 2023 Jan 16;13:1098549. doi: 10.3389/fpls.2022.1098549. eCollection 2022,wenxiangyang2003@163.com,The results showed that Pt13024 was identified as an effector and localized in the cytoplasm and nucleus.,Y Qi 2023,2023,1 gene,Qi-2022-Wheat leaf rust fungus effector Pt1302,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21538,PHI:123918,,no data found,GenBank,OM735615,,,,CEP50,,,,,,,48100,Alternaria solani,,HWC-168,early blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Favorita,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36877688,PubMed,10.1371/journal.pone.0281530,PLoS One. 2023 Mar 6;18(3):e0281530. doi: 10.1371/journal.pone.0281530. eCollection 2023,zhujiehua@hebau.edu.cn,"The deletion of AsCEP50 significantly reduced virulence, melanin production and penetration of A. solani.",C Wang 2023,2023,1 gene,Wang-2023-Identification and functional analys,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21539,PHI:123919,UniProt,P0AG20,GenBank,AAA03237,,,K-12,relA,,,,,,PHI:123920,562,Escherichia coli,574521,E2348/69,neonatal meningitis,nematodes,6239,Caenorhabditis elegans (related: roundworm),SS104,,,larva,GTP pyrophosphokinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36937293,PubMed,10.3389/fmicb.2023.1121715,Front Microbiol. 2023 Mar 2;14:1121715. doi: 10.3389/fmicb.2023.1121715. eCollection 2023,jwy706@kangwon.ac.kr,Depletion of relA and spoT attenuated the virulence of E2348/69 in a Caenorhabditis elegans infection model.,J B Lee 2023,2023,2 genes,Lee-2023-Mutating both relA and spoT of entero,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21540,PHI:123920,UniProt,P0AG24,GenBank,AAC76674,,,K-12,spoT,,,,,,PHI:123919,562,Escherichia coli,574521,E2348/69,neonatal meningitis,nematodes,6239,Caenorhabditis elegans (related: roundworm),SS104,,,larva,bifunctional (p)ppGpp synthase/hydrolase SpoT,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36937293,PubMed,10.3389/fmicb.2023.1121715,Front Microbiol. 2023 Mar 2;14:1121715. doi: 10.3389/fmicb.2023.1121715. eCollection 2023,jwy706@kangwon.ac.kr,Depletion of relA and spoT attenuated the virulence of E2348/69 in a Caenorhabditis elegans infection model.,J B Lee 2023,2023,2 genes,Lee-2023-Mutating both relA and spoT of entero,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21541,PHI:123921,UniProt,A0A2U9ACM3,GenBank,AWO72248,,,,pks14,,,,,,,176275,Beauveria bassiana,,BCC 2660,white muscardine,moths,7107,Spodoptera exigua (related: beet armyworm),,,,larva,polyketide synthase gene,,,,increased virulence (hypervirulence),,,,,,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36984865,PubMed,10.3390/metabo13030425,Metabolites. 2023 Mar 14;13(3):425. doi: 10.3390/metabo13030425,ylyang@gate.sinica.edu.tw,"F30 and FH virulence increased significantly by 177–187% and 18% on days 4 and days 7 after inoculation, compared to the wild type.",W Toopaang 2023,2023,2 genes,Toopaang-2023-Metabolomic Analysis Demonstrate,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21542,PHI:123922,UniProt,A0A1W5T7B8,GenBank,ARF07871,,,,pks15,,,,,,,176275,Beauveria bassiana,,BCC 2660,white muscardine,moths,7107,Spodoptera exigua (related: beet armyworm),,,,larva,polyketide synthase gene,,,,increased virulence (hypervirulence),,,,,,increased,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36984865,PubMed,10.3390/metabo13030425,Metabolites. 2023 Mar 14;13(3):425. doi: 10.3390/metabo13030425,ylyang@gate.sinica.edu.tw,"OEpks15 strains 10, 14, and 16 exhibited increased insect virulence by 150%, 134%, and 128%, respectively, on day 7 compared to the wild type.",W Toopaang 2023,2023,2 genes,Toopaang-2023-Metabolomic Analysis Demonstrate,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21543,PHI:123923,UniProt,P0CU91,,,,,,RXLR131,,,,,,,143451,Plasmopara viticola,,JL-7-2,downy mildew (grape),eudicots,29760,Vitis vinifera (related: wine grape),,,,seedling,effector protein,,,signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,NN,30945786,PubMed,10.1111/mpp.12790,Mol Plant Pathol. 2019 Jun;20(6):765-783. doi: 10.1111/mpp.12790. Epub 2019 Apr 4,Jiang.lu@sjtu.edu.cn,PvRXLR131 in Colletotrichum gloeosporioides significantly enhanced its pathogenicity on grapevine leaves.,X Lan 2019,2019,1 gene,Lan-2019-Plasmopara viticola effector PvRXLR13,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21544,PHI:123923,UniProt,P0CU91,,,,,,RXLR131,,,,,,,143451,Plasmopara viticola,,JL-7-2,downy mildew (grape),eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,effector protein,,,signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants; functional test in host: transient expression,,,NN,30945786,PubMed,10.1111/mpp.12790,Mol Plant Pathol. 2019 Jun;20(6):765-783. doi: 10.1111/mpp.12790. Epub 2019 Apr 4,Jiang.lu@sjtu.edu.cn,Transient expression of PvRXLR131 in Nicotiana benthamiana leaves could also suppress different elicitor-triggered cell death and inhibit plant resistance to Phytophthora capsici,X Lan 2019,2019,1 gene,Lan-2019-Plasmopara viticola effector PvRXLR13,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21545,PHI:123923,UniProt,P0CU91,,,,,,RXLR131,,,,,,,143451,Plasmopara viticola,,JL-7-2,downy mildew (grape),eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,seedling,effector protein,,,signalling pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,other evidence: transgenic plants,,,NN,30945786,PubMed,10.1111/mpp.12790,Mol Plant Pathol. 2019 Jun;20(6):765-783. doi: 10.1111/mpp.12790. Epub 2019 Apr 4,Jiang.lu@sjtu.edu.cn,Constitutive expression of PvRXLR131 in Arabidopsis promoted Pseudomonas syringae DC3000 and P. syringae DC3000 (hrcC-) growth as well as suppressed defence-related callose deposition.,X Lan 2019,2019,1 gene,Lan-2019-Plasmopara viticola effector PvRXLR13,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21546,PHI:123924,,no data found,,,,,,Avh113,,,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,seedling; hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36972124,PubMed,10.1111/pbi.14043,Plant Biotechnol J. 2023 Mar 27. doi: 10.1111/pbi.14043. Online ahead of print,qyl588@gmail.com,"Compared with the WT strain, the three PsAvh113 knockout mutants showed no difference in growth but had a significantly reduced ability to cause disease.",X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae effector PsAvh113,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21547,PHI:123924,,no data found,,,,,,Avh113,,IR1 region was substituted with alanine residues,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36972124,PubMed,10.1111/pbi.14043,Plant Biotechnol J. 2023 Mar 27. doi: 10.1111/pbi.14043. Online ahead of print,qyl588@gmail.com,PsAvh113ΔIR1 induced strong disease symptoms and viral RNA accumulation.,X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae effector PsAvh113,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21548,PHI:123924,,no data found,,,,,,Avh113,,IR2 region was substituted with alanine residues,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36972124,PubMed,10.1111/pbi.14043,Plant Biotechnol J. 2023 Mar 27. doi: 10.1111/pbi.14043. Online ahead of print,qyl588@gmail.com,PsAvh113ΔIR2 caused slight disease symptoms and lower viral RNA accumulation in the VIVE assay.,X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae effector PsAvh113,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21549,PHI:123924,,no data found,,,,,,Avh113,,Ser108 with Met (S108M),,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36972124,PubMed,10.1111/pbi.14043,Plant Biotechnol J. 2023 Mar 27. doi: 10.1111/pbi.14043. Online ahead of print,qyl588@gmail.com,"Similar to PsAvh113, PsAvh113(S108M) induced severe disease symptoms and higher viral RNA accumulation.",X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae effector PsAvh113,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21550,PHI:123924,,no data found,,,,,,Avh113,,Met122 with Ser (M122S),,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36972124,PubMed,10.1111/pbi.14043,Plant Biotechnol J. 2023 Mar 27. doi: 10.1111/pbi.14043. Online ahead of print,qyl588@gmail.com,PsAvh113M122S caused mild disease symptoms and lower viral RNA accumulation.,X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae effector PsAvh113,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21551,PHI:123924,,no data found,,,,,,Avh113,,Ser108 with Met and Met122 with Ser (S108M/M122S),,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36972124,PubMed,10.1111/pbi.14043,Plant Biotechnol J. 2023 Mar 27. doi: 10.1111/pbi.14043. Online ahead of print,qyl588@gmail.com,PsAvh113S108M/M122S caused mild disease symptoms and lower viral RNA accumulation.,X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae effector PsAvh113,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21552,PHI:123924,,no data found,,,,,,Avh113,,IR1 region was substituted with alanine residues,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,root,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36972124,PubMed,10.1111/pbi.14043,Plant Biotechnol J. 2023 Mar 27. doi: 10.1111/pbi.14043. Online ahead of print,qyl588@gmail.com,PsAvh113ΔIR1 induced strong disease symptoms and viral RNA accumulation.,X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae effector PsAvh113,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21553,PHI:123924,,no data found,,,,,,Avh113,,IR2 region was substituted with alanine residues,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),,,,root,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,36972124,PubMed,10.1111/pbi.14043,Plant Biotechnol J. 2023 Mar 27. doi: 10.1111/pbi.14043. Online ahead of print,qyl588@gmail.com,PsAvh113ΔIR2 caused slight disease symptoms and lower viral RNA accumulation in the VIVE assay.,X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae effector PsAvh113,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21554,PHI:123925,UniProt,A0A1D9PUQ1,GenBank,APA06396,,,1980,TOR (Sscle_02g011660),chromosome 2,,,,,,5180,Sclerotinia sclerotiorum,,UF-1,white mold,eudicots,3847,Glycine max (related: soybean),cv. William 82; cv. JI 1,,,leaf,regulatory protein,,,TOR signaling pathway,reduced virulence,,,,,no lesion,,,reduced,,no,Congo red; calcofluor white; sodium dodecyl sulphate (SDS); NaCl; KCl; D-sorbitol; glucose,Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; glucose: CHEBI:17234,,,,,altered gene expression / gene regulation: silencing,,,NN,36943069,PubMed,10.1128/spectrum.00013-23,Microbiol Spectr. 2023 Mar 21;11(2):e0001323. doi: 10.1128/spectrum.00013-23. Online ahead of print,panhongyu@jlu.edu.cn,"The virulence of SsTOR-T1-, SsTOR-T2-, and SsTOR-T3-silenced strains were significantly lower than that of the wild type.",W Jiao 2023,2023,1 gene,Jiao-2023-Cross-Talk and Multiple Control of T,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21555,PHI:123925,UniProt,A0A1D9PUQ1,GenBank,APA06396,,,1980,TOR (Sscle_02g011660),chromosome 2,,,,,,5180,Sclerotinia sclerotiorum,,UF-1,white mold,eudicots,3885,Phaseolus vulgaris (related: kidney bean),,,,leaf,regulatory protein,,,TOR signaling pathway,reduced virulence,,,,,no lesion,,,reduced,,no,Congo red; calcofluor white; sodium dodecyl sulphate (SDS); NaCl; KCl; D-sorbitol; glucose,Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; glucose: CHEBI:17234,,,,,altered gene expression / gene regulation: silencing,,,NN,36943069,PubMed,10.1128/spectrum.00013-23,Microbiol Spectr. 2023 Mar 21;11(2):e0001323. doi: 10.1128/spectrum.00013-23. Online ahead of print,panhongyu@jlu.edu.cn,"The virulence of SsTOR-T1-, SsTOR-T2-, and SsTOR-T3-silenced strains were significantly lower than that of the wild type.",W Jiao 2023,2023,1 gene,Jiao-2023-Cross-Talk and Multiple Control of T,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21556,PHI:123925,UniProt,A0A1D9PUQ1,GenBank,APA06396,,,1980,TOR (Sscle_02g011660),chromosome 2,,,,,,5180,Sclerotinia sclerotiorum,,UF-1,white mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,leaf,regulatory protein,,,TOR signaling pathway,reduced virulence,,,,,no lesion,,,reduced,,no,Congo red; calcofluor white; sodium dodecyl sulphate (SDS); NaCl; KCl; D-sorbitol; glucose,Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; glucose: CHEBI:17234,,,,,altered gene expression / gene regulation: silencing,,,NN,36943069,PubMed,10.1128/spectrum.00013-23,Microbiol Spectr. 2023 Mar 21;11(2):e0001323. doi: 10.1128/spectrum.00013-23. Online ahead of print,panhongyu@jlu.edu.cn,"The virulence of SsTOR-T1-, SsTOR-T2-, and SsTOR-T3-silenced strains were significantly lower than that of the wild type.",W Jiao 2023,2023,1 gene,Jiao-2023-Cross-Talk and Multiple Control of T,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21557,PHI:123925,UniProt,A0A1D9PUQ1,GenBank,APA06396,,,1980,TOR (Sscle_02g011660),chromosome 2,,,,,,5180,Sclerotinia sclerotiorum,,UF-1,white mold,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,regulatory protein,,,TOR signaling pathway,reduced virulence,,,,,no lesion,,,reduced,,no,Congo red; calcofluor white; sodium dodecyl sulphate (SDS); NaCl; KCl; D-sorbitol; glucose,Congo red: CHEBI:34653; SDS: CHEBI:8984; calcofluor white (CFW): CHEBI:50011; NaCl: CHEBI:26710; KCl: CHEBI:32588; D-sorbitol: CHEBI:17924; glucose: CHEBI:17234,,,,,altered gene expression / gene regulation: silencing,,,NN,36943069,PubMed,10.1128/spectrum.00013-23,Microbiol Spectr. 2023 Mar 21;11(2):e0001323. doi: 10.1128/spectrum.00013-23. Online ahead of print,panhongyu@jlu.edu.cn,"The virulence of SsTOR-T1-, SsTOR-T2-, and SsTOR-T3-silenced strains were significantly lower than that of the wild type.",W Jiao 2023,2023,1 gene,Jiao-2023-Cross-Talk and Multiple Control of T,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21558,PHI:123926,UniProt,E9DVC9,GenBank,EFY92306,,,CQMa 102,Dct1 (XP_007807917.1),unknown,,,,,,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,nymph,C4-dicarboxylate transporter,,,gluconeogenesis pathway,unaffected pathogenicity,,,,,,reduced,,increased,reduced,no,calcofluor white; D-sorbitol,calcofluor white (CFW): CHEBI:50011; D-sorbitol: CHEBI:17924,,,,,gene deletion: full,,,NN,36941435,PubMed,10.1007/s00253-023-12471-x,Appl Microbiol Biotechnol. 2023 May;107(9):2969-2982. doi: 10.1007/s00253-023-12471-x. Epub 2023 Mar 21,yuxianxia@cqu.edu.cn,LT50 of ΔMaDct1 had no significant difference with that of wild type in both topical inoculation and injection assays.,Y Luo 2023,2023,2 genes,Luo-2023-Tetracarboxylic acid transporter regu,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21559,PHI:123926,UniProt,E9DVC9,GenBank,EFY92306,,,CQMa 102,Dct1 (XP_007807917.1),unknown,,,,,PHI:123927,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,nymph,C4-dicarboxylate transporter,,,gluconeogenesis pathway,unaffected pathogenicity,,,,,,wild type,,increased,wild type,no,calcofluor white; D-sorbitol,calcofluor white (CFW): CHEBI:50011; D-sorbitol: CHEBI:17924,,,,,gene deletion: full,,,NN,36941435,PubMed,10.1007/s00253-023-12471-x,Appl Microbiol Biotechnol. 2023 May;107(9):2969-2982. doi: 10.1007/s00253-023-12471-x. Epub 2023 Mar 21,yuxianxia@cqu.edu.cn,LT50 of ΔΔMaDct had no significant differences with that of wild type in both topical inoculation and injection assays.,Y Luo 2023,2023,2 genes,Luo-2023-Tetracarboxylic acid transporter regu,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21560,PHI:123927,UniProt,E9E959,GenBank,EFY87563,,,CQMa 102,Dct2 (XP_007812747.1),unknown,,,,,PHI:123926,92637,Metarhizium acridum,655827,CQMa 102,,grasshoppers,7004,Locusta migratoria (related: migratory locust),subsp. manilensis,,,nymph,C4-dicarboxylate transporter,,,gluconeogenesis pathway,unaffected pathogenicity,,,,,,wild type,,increased,wild type,no,calcofluor white; D-sorbitol,calcofluor white (CFW): CHEBI:50011; D-sorbitol: CHEBI:17924,,,,,gene deletion: full,,,NN,36941435,PubMed,10.1007/s00253-023-12471-x,Appl Microbiol Biotechnol. 2023 May;107(9):2969-2982. doi: 10.1007/s00253-023-12471-x. Epub 2023 Mar 21,yuxianxia@cqu.edu.cn,LT50 of ΔΔMaDct had no significant differences with that of wild type in both topical inoculation and injection assays.,Y Luo 2023,2023,2 genes,Luo-2023-Tetracarboxylic acid transporter regu,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21561,PHI:123928,UniProt,A0A384JBC5,GenBank,ATZ47741,,,B05.10,spl1 (Bcin03g00500),chromosome BCIN03,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),cv. Moneymaker,,,leaf,cerato-platanin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36968352,PubMed,10.3389/fpls.2023.1107888,Front Plant Sci. 2023 Mar 8;14:1107888. doi: 10.3389/fpls.2023.1107888. eCollection 2023,jan.vankan@wur.nl,The virulence of the Bcspl1 target site mutant was identical to the wild type fungus.,S Qin 2023,2023,1 gene,Qin-2023-Molecular characterization of cross-k,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21562,PHI:123929,UniProt,Q5HDJ9,GenBank,AAG23888,,,COL,tcaA,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,membrane-associated protein TcaA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36865143,PubMed,10.1101/2023.02.23.529713,bioRxiv. 2023 Feb 23:2023.02.23.529713. doi: 10.1101/2023.02.23.529713. Preprint,ruth.massey@bristol.ac.uk,The mortality rate of the proportion of patients infected with a S. aureus strain with the wild type tcaA gene was significantly higher compared to those infected with a mutated tcaA gene.,E J A Douglas 2023,2023,1 gene,Douglas-2023-Extensive re-modelling of the cel,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21563,PHI:123929,UniProt,Q5HDJ9,GenBank,AAG23888,,,COL,tcaA,,,,,,,1280,Staphylococcus aureus,,JE2,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; blood; kidney,membrane-associated protein TcaA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36865143,PubMed,10.1101/2023.02.23.529713,bioRxiv. 2023 Feb 23:2023.02.23.529713. doi: 10.1101/2023.02.23.529713. Preprint,ruth.massey@bristol.ac.uk,TcaA contributes positively to disease severity by the wild type strain outcompeting the tcaA mutant in mice.,E J A Douglas 2023,2023,1 gene,Douglas-2023-Extensive re-modelling of the cel,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21564,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21565,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21566,PHI:123932,,no data found,,,,,,EPC3 (g_11868),,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21567,PHI:123933,,no data found,,,,,,EPC4 (g_04157),,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21568,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21569,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21570,PHI:123932,,no data found,,,,,,EPC3 (g_11868),,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21571,PHI:123933,,no data found,,,,,,EPC4 (g_04157),,,,,,,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21572,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,PHI:123931,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21573,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,PHI:123930,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21574,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,PHI:123931; PHI:123932,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21575,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,PHI:123930; PHI:123932,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21576,PHI:123932,,no data found,,,,,,EPC3 (g_11868),,,,,,PHI:123930; PHI:123931,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21577,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,PHI:123931; PHI:123932; PHI:123933,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,loss of lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21578,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,PHI:123930; PHI:123932; PHI:123933,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,loss of lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21579,PHI:123932,,no data found,,,,,,EPC3 (g_11868),,,,,,PHI:123930; PHI:123931; PHI:123933,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,loss of lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21580,PHI:123933,,no data found,,,,,,EPC4 (g_04157),,,,,,PHI:123930; PHI:123931; PHI:123932,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,loss of lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21581,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,PHI:123931,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3656,Cucumis melo (related: muskmelon),cv. Lennon,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21582,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,PHI:123930,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3656,Cucumis melo (related: muskmelon),cv. Lennon,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21583,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,PHI:123931; PHI:123932,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3656,Cucumis melo (related: muskmelon),cv. Lennon,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21584,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,PHI:123930; PHI:123932,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3656,Cucumis melo (related: muskmelon),cv. Lennon,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21585,PHI:123932,,no data found,,,,,,EPC3 (g_11868),,,,,,PHI:123930; PHI:123931,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3656,Cucumis melo (related: muskmelon),cv. Lennon,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21586,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,PHI:123931; PHI:123932; PHI:123933,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3656,Cucumis melo (related: muskmelon),cv. Lennon,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,loss of lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21587,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,PHI:123930; PHI:123932; PHI:123933,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3656,Cucumis melo (related: muskmelon),cv. Lennon,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,loss of lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21588,PHI:123932,,no data found,,,,,,EPC3 (g_11868),,,,,,PHI:123930; PHI:123931; PHI:123933,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3656,Cucumis melo (related: muskmelon),cv. Lennon,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,loss of lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21589,PHI:123933,,no data found,,,,,,EPC4 (g_04157),,,,,,PHI:123930; PHI:123931; PHI:123932,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3656,Cucumis melo (related: muskmelon),cv. Lennon,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,loss of lesion,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21590,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,PHI:123931,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21591,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,PHI:123930,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21592,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,PHI:123931; PHI:123932,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21593,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,PHI:123930; PHI:123932,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21594,PHI:123932,,no data found,,,,,,EPC3 (g_11868),,,,,,PHI:123930; PHI:123931,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21595,PHI:123930,,no data found,,,,,,EPC1 (g_04238),,,,,,PHI:123931; PHI:123932; PHI:123933,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21596,PHI:123931,,no data found,,,,,,EPC2 (g_10510),,,,,,PHI:123930; PHI:123932; PHI:123933,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21597,PHI:123932,,no data found,,,,,,EPC3 (g_11868),,,,,,PHI:123930; PHI:123931; PHI:123933,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21598,PHI:123933,,no data found,,,,,,EPC4 (g_04157),,,,,,PHI:123930; PHI:123931; PHI:123932,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,C. orbiculare effector genes that are differentially required for fungal virulence.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21599,PHI:123934,,no data found,,,,,,g_13573,,,,,,PHI:123935,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21600,PHI:123935,,no data found,,,,,,g_01222,,,,,,PHI:123934,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21601,PHI:123934,,no data found,,,,,,g_13573,,,,,,PHI:123935; PHI:123936,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21602,PHI:123935,,no data found,,,,,,g_01222,,,,,,PHI:123934; PHI:123936,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21603,PHI:123936,,no data found,,,,,,g_01264,,,,,,PHI:123934; PHI:123935,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21604,PHI:123934,,no data found,,,,,,g_13573,,,,,,PHI:123935; PHI:123936; PHI:123937,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21605,PHI:123935,,no data found,,,,,,g_01222,,,,,,PHI:123934; PHI:123936; PHI:123937,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21606,PHI:123936,,no data found,,,,,,g_01264,,,,,,PHI:123934; PHI:123935; PHI:123937,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21607,PHI:123937,,no data found,,,,,,g_09665,,,,,,PHI:123934; PHI:123935; PHI:123936,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21608,PHI:123934,,no data found,,,,,,g_13573,,,,,,PHI:123935; PHI:123936; PHI:123937; PHI:123938,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21609,PHI:123935,,no data found,,,,,,g_01222,,,,,,PHI:123934; PHI:123936; PHI:123937; PHI:123938,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21610,PHI:123936,,no data found,,,,,,g_01264,,,,,,PHI:123934; PHI:123935; PHI:123937; PHI:123938,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21611,PHI:123937,,no data found,,,,,,g_09665,,,,,,PHI:123934; PHI:123935; PHI:123936; PHI:123938,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21612,PHI:123938,,no data found,,,,,,g_04549,,,,,,PHI:123934; PHI:123935; PHI:123936; PHI:123937,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of cucurbits.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21613,PHI:123934,,no data found,,,,,,g_13573,,,,,,PHI:123935,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21614,PHI:123935,,no data found,,,,,,g_01222,,,,,,PHI:123934,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21615,PHI:123934,,no data found,,,,,,g_01264,,,,,,PHI:123935; PHI:123936,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21616,PHI:123935,,no data found,,,,,,g_01222,,,,,,PHI:123934; PHI:123936,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21617,PHI:123936,,no data found,,,,,,g_01264,,,,,,PHI:123934; PHI:123935,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21618,PHI:123934,,no data found,,,,,,g_13573,,,,,,PHI:123935; PHI:123936; PHI:123937,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21619,PHI:123935,,no data found,,,,,,g_01222,,,,,,PHI:123934; PHI:123936; PHI:123937,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21620,PHI:123936,,no data found,,,,,,g_01264,,,,,,PHI:123934; PHI:123935; PHI:123937,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21621,PHI:123937,,no data found,,,,,,g_09665,,,,,,PHI:123934; PHI:123935; PHI:123936,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21622,PHI:123934,,no data found,,,,,,g_13573,,,,,,PHI:123935; PHI:123936; PHI:123937; PHI:123938,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21623,PHI:123935,,no data found,,,,,,g_01222,,,,,,PHI:123934; PHI:123936; PHI:123937; PHI:123938,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21624,PHI:123936,,no data found,,,,,,g_01264,,,,,,PHI:123934; PHI:123935; PHI:123937; PHI:123938,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21625,PHI:123937,,no data found,,,,,,g_09665,,,,,,PHI:123934; PHI:123935; PHI:123936; PHI:123938,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21626,PHI:123938,,no data found,,,,,,g_04549,,,,,,PHI:123934; PHI:123935; PHI:123936; PHI:123937,5465,Colletotrichum orbiculare,,104-T,anthracnose (Cucurbitaceae),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesion,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36939621,PubMed,10.1111/nph.18790,New Phytol. 2023 May;238(4):1578-1592. doi: 10.1111/nph.18790. Epub 2023 Mar 20,takano.yoshitaka.2x@kyoto-u.ac.jp,Hostblind gene expression include virulence factors for infection of N. benthamiana.,Y Inoue 2023,2023,9 genes,Inoue-2023-Selective deployment of virulence e,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21627,PHI:123939,,no data found,,,,,,hopS2b,,,,,,,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21628,PHI:123940,,no data found,,,,,,hopAZ1a,,,,,,,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21629,PHI:123939,,no data found,,,,,,hopS2b,,,,,,PHI:123940,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21630,PHI:123940,,no data found,,,,,,hopAZ1a,,,,,,PHI:123939,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21631,PHI:123941,,no data found,,,,,,hopH1a,,,,,,PHI:123942,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21632,PHI:123942,,no data found,,,,,,hopZ5a,,,,,,PHI:123941,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21633,PHI:123941,,no data found,,,,,,hopH1a,,,,,,PHI:123942; PHI:123943,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21634,PHI:123942,,no data found,,,,,,hopZ5a,,,,,,PHI:123941; PHI:123943,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21635,PHI:123943,,no data found,,,,,,avrPto1b,,,,,,PHI:123941; PHI:123942,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21636,PHI:123941,,no data found,,,,,,hopH1a,,,,,,PHI:123942; PHI:123943; PHI:123944,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21637,PHI:123942,,no data found,,,,,,hopZ5a,,,,,,PHI:123941; PHI:123943; PHI:123944,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21638,PHI:123943,,no data found,,,,,,avrPto1b,,,,,,PHI:123941; PHI:123942; PHI:123944,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21639,PHI:123944,,no data found,,,,,,avrRpm1a,,,,,,PHI:123941; PHI:123942; PHI:123943,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21640,PHI:123941,,no data found,,,,,,hopH1a,,,,,,PHI:123942; PHI:123943; PHI:123944; PHI:123945,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21641,PHI:123942,,no data found,,,,,,hopZ5a,,,,,,PHI:123941; PHI:123943; PHI:123944; PHI:123945,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21642,PHI:123943,,no data found,,,,,,avrPto1b,,,,,,PHI:123941; PHI:123942; PHI:123944; PHI:123945,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21643,PHI:123944,,no data found,,,,,,avrRpm1a,,,,,,PHI:123941; PHI:123942; PHI:123943; PHI:123945,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21644,PHI:123945,,no data found,,,,,,HopF1e,,,,,,PHI:123941; PHI:123942; PHI:123943; PHI:123944,317,Pseudomonas syringae,1095103,pv. actinidiae biovar 3 strain ICMP 18884,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),var. chinensis cv. Hort16A,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36856342,PubMed,10.1111/nph.18848,New Phytol. 2023 May;238(4):1605-1619. doi: 10.1111/nph.18848. Epub 2023 Mar 20,matt.templeton@plantandfood.co.nz,Effector knockout strains of the Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) in kiwifruit host contribute to Psa3 virulence.,J Jayaraman 2023,2023,7 genes,Jayaraman-2023-Contrasting effector profiles b,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21645,PHI:123946,UniProt,A0A0J9WP80,GenBank,KNB08567,,,4287,FTF2 (FOXG_09390),chromosome 9,,,,,,5507,Fusarium oxysporum,,f. sp. phaseoli strain FOP-SP4,Fusarium wilt,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blanca Riñón,,,root; hypocotyl,transcription factor,,,,loss of pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,NN,36986302,PubMed,10.3390/pathogens12030380,Pathogens. 2023 Feb 26;12(3):380. doi: 10.3390/pathogens12030380,josediaz@usal.es,"FTF2 as a negative regulator, it is required for full virulence in Phaseolus vulgaris L.",V Casado-Del Castillo 2023,2023,2 genes,Casado-Del Cast-2023-The Role of the Fusarium,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21646,PHI:123947,UniProt,A0A0J9WP80,GenBank,KNB08567,,,4287,FTF2 (FOXG_09390),chromosome 9,,,,,,5507,Fusarium oxysporum,,f. sp. phaseoli strain FOP-SP1,Fusarium wilt,eudicots,3885,Phaseolus vulgaris (related: kidney bean),cv. Blanca Riñón,,,root; hypocotyl,transcription factor,,,,loss of pathogenicity,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,NN,36986302,PubMed,10.3390/pathogens12030380,Pathogens. 2023 Feb 26;12(3):380. doi: 10.3390/pathogens12030380,josediaz@usal.es,"FTF2 as a negative regulator, it is required for full virulence in Phaseolus vulgaris L.",V Casado-Del Castillo 2023,2023,2 genes,Casado-Del Cast-2023-The Role of the Fusarium,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21647,PHI:123948,UniProt,Q9HG08,GenBank,NC_037311,,,B05.10,Bmp1,chromosome 2,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romana,,,leaf,MAP kinase,,,MAP kinase pathway,reduced virulence,,,,,smaller necrotic lesions,,,wild type,reduced,no,,,,,,,gene deletion: full,,,NN,36902297,PubMed,10.3390/ijms24054869,Int J Mol Sci. 2023 Mar 2;24(5):4869. doi: 10.3390/ijms24054869,susanna.pecchia@unipi.it,BcBmp1-dsRNA-treated leaves showed strongly reduced necrotic lesions at the inoculation site.,M Spada 2023,2023,2 genes,Spada-2023-Knockdown of Bmp1 and Pls1 Virulenc,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21648,PHI:123949,UniProt,Q8J0E3,GenBank,NC_037318,,,B05.10,Pls1,chromosome 9,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4236,Lactuca sativa (related: garden lettuce),cv. Romana,,,leaf,tetraspanin,,,,reduced virulence,,,,,smaller necrotic lesions,,,reduced,wild type,no,,,,,,,gene deletion: full,,,NN,36902297,PubMed,10.3390/ijms24054869,Int J Mol Sci. 2023 Mar 2;24(5):4869. doi: 10.3390/ijms24054869,susanna.pecchia@unipi.it,BcPls1-dsRNA-treated leaves showed strongly reduced necrotic lesions at the inoculation site.,M Spada 2023,2023,2 genes,Spada-2023-Knockdown of Bmp1 and Pls1 Virulenc,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21649,PHI:123950,UniProt,A0A656K4Z7,GenBank,EPN69377,,,ICMP 19096,hrcC,,,,,,,317,Pseudomonas syringae,,pv. actinidiae strain AH.01,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),cv. Hongyang; cv. Guichang,,,leaf,type III secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36902028,PubMed,10.3390/ijms24054597,Int J Mol Sci. 2023 Feb 27;24(5):4597. doi: 10.3390/ijms24054597,liuyongsheng1122@ahau.edu.cn,The plantlets inoculated with the ΔhrcC mutant appeared healthy and asymptomatic.,B Liu 2023,2023,4 genes,Liu-2023-dCas9-BE3 and dCas12a-BE3 Systems Med,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21650,PHI:123951,UniProt,A0A3M4L7Z2,GenBank,RMQ37599,,,ICMP 19096,hopR1,,,,,,,317,Pseudomonas syringae,,pv. actinidiae strain AH.01,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),cv. Hongyang; cv. Guichang,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36902028,PubMed,10.3390/ijms24054597,Int J Mol Sci. 2023 Feb 27;24(5):4597. doi: 10.3390/ijms24054597,liuyongsheng1122@ahau.edu.cn,Plantlets infected by ΔhopR1 were lighter than those infected with Psa.,B Liu 2023,2023,4 genes,Liu-2023-dCas9-BE3 and dCas12a-BE3 Systems Med,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21651,PHI:123952,UniProt,S6TW99,GenBank,EPN33709,,,ICMP 19096,hopF2,,,,,,,317,Pseudomonas syringae,,pv. actinidiae strain AH.01,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),cv. Hongyang; cv. Guichang,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36902028,PubMed,10.3390/ijms24054597,Int J Mol Sci. 2023 Feb 27;24(5):4597. doi: 10.3390/ijms24054597,liuyongsheng1122@ahau.edu.cn,Virulence of ΔhopF2 is seen to be decreased.,B Liu 2023,2023,4 genes,Liu-2023-dCas9-BE3 and dCas12a-BE3 Systems Med,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21652,PHI:123953,UniProt,A0A345Z9L9,GenBank,AXK59705,,,Psa743,hopAO2,,,,,,,317,Pseudomonas syringae,,pv. actinidiae strain AH.01,bacterial canker,eudicots,3625,Actinidia chinensis (related: zhong hua mi hou tao),cv. Hongyang; cv. Guichang,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,36902028,PubMed,10.3390/ijms24054597,Int J Mol Sci. 2023 Feb 27;24(5):4597. doi: 10.3390/ijms24054597,liuyongsheng1122@ahau.edu.cn,Virulence of ΔhopAO2 is seen to be decreased.,B Liu 2023,2023,4 genes,Liu-2023-dCas9-BE3 and dCas12a-BE3 Systems Med,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21653,PHI:123954,UniProt,A0A6L8MXT9,GenBank,MYN69897,,,10-36905,GntR (ZY05719_02215),,,,,,,1307,Streptococcus suis,,SS2,septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; liver; brain; blood,transcription factor,,,phosphorylation pathway,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36913374,PubMed,10.1371/journal.ppat.1011227,PLoS Pathog. 2023 Mar 13;19(3):e1011227. doi: 10.1371/journal.ppat.1011227. eCollection 2023 Mar,fhj@njau.edu.cn,Phosphorylation of GntR by STK resulted in a significant reduction in lethality and pathogenicity in mice,K Niu 2023,2023,2 genes,Niu-2023-Phosphorylation of GntR reduces Strep,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21654,PHI:123954,UniProt,A0A6L8MXT9,GenBank,MYN69897,,,10-36905,GntR (ZY05719_02215),,STK phosphorylated GntR at Ser-41,,,,,1307,Streptococcus suis,,SS2,septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; liver; brain; blood,transcription factor,,,phosphorylation pathway,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,NN,36913374,PubMed,10.1371/journal.ppat.1011227,PLoS Pathog. 2023 Mar 13;19(3):e1011227. doi: 10.1371/journal.ppat.1011227. eCollection 2023 Mar,fhj@njau.edu.cn,"The mice injected with the GntR-S41E strain showed a significantly increased rate compared to mice injected with the WT SS2, which showed 20% survival.",K Niu 2023,2023,2 genes,Niu-2023-Phosphorylation of GntR reduces Strep,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21655,PHI:123954,UniProt,A0A6L8MXT9,GenBank,MYN69897,,,10-36905,GntR (ZY05719_02215),,STK phosphorylated GntR at Ser-41,,,,,1307,Streptococcus suis,,SS2,septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; liver; brain; blood,transcription factor,,,phosphorylation pathway,reduced virulence,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene mutation,,,NN,36913374,PubMed,10.1371/journal.ppat.1011227,PLoS Pathog. 2023 Mar 13;19(3):e1011227. doi: 10.1371/journal.ppat.1011227. eCollection 2023 Mar,fhj@njau.edu.cn,"The mice injected with the GntR-S41A strain showed a significantly increased rate compared to mice injected with the WT SS2, which showed 20% survival.",K Niu 2023,2023,2 genes,Niu-2023-Phosphorylation of GntR reduces Strep,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21656,PHI:123954,UniProt,A0A7G1JLA3,GenBank,BCK43550,,,DAT299,nox,,,,,,,1307,Streptococcus suis,,SS2,septicemia; meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; spleen; liver; brain; blood,NADH oxidase,,,,loss of pathogenicity,,,,,,,,wild type,,no,H2O2,H2O2: CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,36913374,PubMed,10.1371/journal.ppat.1011227,PLoS Pathog. 2023 Mar 13;19(3):e1011227. doi: 10.1371/journal.ppat.1011227. eCollection 2023 Mar,fhj@njau.edu.cn,"GntR phosphorylation could inhibit the transcription of nox, which impaired the ability of SS2 to resist oxidative stress and virulence.",K Niu 2023,2023,2 genes,Niu-2023-Phosphorylation of GntR reduces Strep,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21657,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407P - B. cinerea adenylate cyclase S1407P single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: paradise apple),,,,fruit,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,,,,,increased,,reduced,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21658,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407A - B. cinerea adenylate cyclase S1407A single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: paradise apple),,,,fruit,adenylate cyclase,,,cAMP signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21659,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407D - B. cinerea adenylate cyclase S1407D single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,283210,Malus pumila (related: paradise apple),,,,fruit,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,,,,,increased,,reduced,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21660,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407P - B. cinerea adenylate cyclase S1407P single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,,,,,increased,,reduced,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21661,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407A - B. cinerea adenylate cyclase S1407A single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,adenylate cyclase,,,cAMP signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21662,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407D - B. cinerea adenylate cyclase S1407D single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,,,,,increased,,reduced,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21663,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407P - B. cinerea adenylate cyclase S1407P single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit; leaf,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,,,,,increased,,reduced,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21664,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407A - B. cinerea adenylate cyclase S1407A single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit; leaf,adenylate cyclase,,,cAMP signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21665,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407D - B. cinerea adenylate cyclase S1407D single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit; leaf,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,,,,,increased,,reduced,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21666,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacP1407S - In situ replenishment strain of B. cinerea adenylate cyclase S1407P single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: Tomato),,,,fruit,adenylate cyclase,,,cAMP signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21667,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407P - B. cinerea adenylate cyclase S1407P single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,,,,,increased,,reduced,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21668,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407A - B. cinerea adenylate cyclase S1407A single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,adenylate cyclase,,,cAMP signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21669,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacS1407D - B. cinerea adenylate cyclase S1407D single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,adenylate cyclase,,,cAMP signaling pathway,reduced virulence,,,,,,increased,,reduced,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21670,PHI:123955,UniProt,Q9P880,GenBank,CAB77164,,,SAS 56,BAC,,bacP1407S - In situ replenishment strain of B. cinerea adenylate cyclase S1407P single amino acid mutation,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: Thale cress),,,,leaf,adenylate cyclase,,,cAMP signaling pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,SDS,SDS: CHEBI:8984,,,,,gene mutation,,,NN,36876105,PubMed,10.3389/fmicb.2023.1112584,Front Microbiol. 2023 Feb 15;14:1112584. doi: 10.3389/fmicb.2023.1112584. eCollection 2023,lxu@bio.ecnu.edu.cn,"B. cinerea adenylate cyclase (BAC) mutation showed it affects the production of conidia, sclerotia and virulence.",Y Cai 2023,2023,1 gene,Cai-2023-Phosphorylation status of a conserved,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21671,PHI:123956,,no data found,,,,,,DCL1 (PVITv1_T038441),,,,,,PHI:123957,143451,Plasmopara viticola,,,downy mildew (grape),eudicots,29760,Vitis vinifera (related: wine grape),cv. Trebbiano,,,leaf,dicer-like (DCL) genes,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,34084177,PubMed,10.3389/fpls.2021.667539,Front Plant Sci. 2021 May 18;12:667539. doi: 10.3389/fpls.2021.667539. eCollection 2021,elena.baraldi@unibo.it,"PvDCL1/2 dsRNA, a chimera of PvDCL1 and PvDCL2, highly affected the virulence of P. viticola.",Z M Haile 2021,2021,2 genes,Haile-2021-Double-Stranded RNA Targeting Dicer,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21672,PHI:123957,,no data found,,,,,,DCL2 (PVITv1_T003331),,,,,,PHI:123956,143451,Plasmopara viticola,,,downy mildew (grape),eudicots,29760,Vitis vinifera (related: wine grape),cv. Trebbiano,,,leaf,dicer-like (DCL) genes,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,34084177,PubMed,10.3389/fpls.2021.667539,Front Plant Sci. 2021 May 18;12:667539. doi: 10.3389/fpls.2021.667539. eCollection 2021,elena.baraldi@unibo.it,"PvDCL1/2 dsRNA, a chimera of PvDCL1 and PvDCL2, highly affected the virulence of P. viticola.",Z M Haile 2021,2021,2 genes,Haile-2021-Double-Stranded RNA Targeting Dicer,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21673,PHI:123958,UniProt,Q9P8D4,GenBank,CAB85704,,,1001,Cdc14,,,,,,,5476,Candida albicans,,HCY109,disseminated candidiasis,moths,7137,Galleria mellonella (related: Greater wax moth),,,,larva,protein-tyrosine-phosphatase,,,cell wall integrity pathway,reduced virulence,,,,,,,,reduced,,no,micafungin; caspofungin,caspofungin: CHEBI:474180; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,NN,36876065,PubMed,10.3389/fmicb.2023.1129155,Front Microbiol. 2023 Feb 16;14:1129155. doi: 10.3389/fmicb.2023.1129155. eCollection 2023,mchall@purdue.edu,Cdc14 activity via cdc14hm mutation severely impaired C. albicans virulence.,K L Milholland 2023,2023,1 gene,Milholland-2023-Cdc14 phosphatase contributes,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21674,PHI:123958,UniProt,Q9P8D4,GenBank,CAB85704,,,1001,Cdc14,,,,,,,5476,Candida albicans,,HCY109,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver,protein-tyrosine-phosphatase,,,cell wall integrity pathway,reduced virulence,,,,,,,,reduced,,no,micafungin; caspofungin,caspofungin: CHEBI:474180; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,NN,36876065,PubMed,10.3389/fmicb.2023.1129155,Front Microbiol. 2023 Feb 16;14:1129155. doi: 10.3389/fmicb.2023.1129155. eCollection 2023,mchall@purdue.edu,Cdc14 activity via cdc14hm mutation severely impaired C. albicans virulence.,K L Milholland 2023,2023,1 gene,Milholland-2023-Cdc14 phosphatase contributes,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21675,PHI:123958,UniProt,Q9P8D4,GenBank,CAB85704,,,1001,Cdc14,,cdc14hm mutation (encoding 414QPRK→ 414AARA substitutions),,,,,5476,Candida albicans,,HCY109,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; liver,protein-tyrosine-phosphatase,,,cell wall integrity pathway,loss of pathogenicity,,,,,,,,reduced,,no,micafungin; caspofungin,caspofungin: CHEBI:474180; micafungin: CHEBI:600520,,,,,gene deletion: full; gene complementation,,,NN,36876065,PubMed,10.3389/fmicb.2023.1129155,Front Microbiol. 2023 Feb 16;14:1129155. doi: 10.3389/fmicb.2023.1129155. eCollection 2023,mchall@purdue.edu,cdc14hm failed to kill any mice.,K L Milholland 2023,2023,1 gene,Milholland-2023-Cdc14 phosphatase contributes,BATCH_121A,2023-04-01,MC,,,,,,,,,,,,,
,,Record 21676,PHI:123959,,no data found,,,,,,SaaS,,,,,,,28901,Salmonella enterica,604,serovar Enteritidis strain NCM61,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; Intestine,small RNAs,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36688642,PubMed,10.1128/spectrum.02938-22,Microbiol Spectr. 2023 Feb 14;11(1):e0293822. doi: 10.1128/spectrum.02938-22. Epub 2023 Jan 23,xlxus@njau.edu.cn,"Compared with ΔsaaS strain-infected mice, there was a quicker death and an approximately 16% lower survival rate in WT-infected mice.",L L Cai 2023,2023,1 gene,"Cai-2023-A Small RNA, SaaS, Promotes Salmonell",BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21677,PHI:123960,,no data found,,,,,,HapX (OP828655),,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),Citrus reticulata cv. Blanco x Fortunella margarita cv. Swingle,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37108881,PubMed,10.3390/jof9040427,J Fungi (Basel). 2023 Mar 29;9(4):427. doi: 10.3390/jof9040427,krchung@nchu.edu.tw,ΔAaHapX induced necrotic lesions at rates and magnitudes similar to the wild type 3 days post inoculation.,J J Wu 2023,2023,5 genes,Wu-2023-The Regulatory Hub of Siderophore Bios,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21678,PHI:123961,,no data found,,,,,,Atf1 (OP828654),,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),Citrus reticulata cv. Blanco x Fortunella margarita cv. Swingle,,,leaf,transcription factor,,,,unaffected pathogenicity,,,,,,,,increased,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37108881,PubMed,10.3390/jof9040427,J Fungi (Basel). 2023 Mar 29;9(4):427. doi: 10.3390/jof9040427,krchung@nchu.edu.tw,ΔAaAtf1 induced necrotic lesions at rates and magnitudes similar to the wild type 3 days post inoculation.,J J Wu 2023,2023,5 genes,Wu-2023-The Regulatory Hub of Siderophore Bios,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21679,PHI:123962,UniProt,A0A177DN61,,,,,,HapB (OP828656),,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),Citrus reticulata cv. Blanco x Fortunella margarita cv. Swingle,,,leaf,CCAAT-binding protein,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37108881,PubMed,10.3390/jof9040427,J Fungi (Basel). 2023 Mar 29;9(4):427. doi: 10.3390/jof9040427,krchung@nchu.edu.tw,"ΔAaHapB, were unable to induce necrotic lesions 3 dpi, even when the leaves were wounded before inoculation.",J J Wu 2023,2023,5 genes,Wu-2023-The Regulatory Hub of Siderophore Bios,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21680,PHI:123963,,no data found,,,,,,HapC (OP828657),,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),Citrus reticulata cv. Blanco x Fortunella margarita cv. Swingle,,,leaf,CCAAT-binding protein,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37108881,PubMed,10.3390/jof9040427,J Fungi (Basel). 2023 Mar 29;9(4):427. doi: 10.3390/jof9040427,krchung@nchu.edu.tw,"ΔAaHapC, were unable to induce necrotic lesions 3 dpi, even when the leaves were wounded before inoculation.",J J Wu 2023,2023,5 genes,Wu-2023-The Regulatory Hub of Siderophore Bios,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21681,PHI:123964,UniProt,A0A177DK87,,,,,,HapE (OP828658),,,,,,,5599,Alternaria alternata,,EV-MIL31,brown spot,eudicots,164113,Citrus x microcarpa (related: calamondin),Citrus reticulata cv. Blanco x Fortunella margarita cv. Swingle,,,leaf,CCAAT-binding protein,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37108881,PubMed,10.3390/jof9040427,J Fungi (Basel). 2023 Mar 29;9(4):427. doi: 10.3390/jof9040427,krchung@nchu.edu.tw,"ΔAaHapE, were unable to induce necrotic lesions 3 dpi, even when the leaves were wounded before inoculation.",J J Wu 2023,2023,5 genes,Wu-2023-The Regulatory Hub of Siderophore Bios,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21682,PHI:123965,UniProt,G4MYQ8,GenBank,EHA55287,,,70-15,Erv14 (MGG_08132),chromosome 2,,,MoPth11; MoWish; MoSho1,UniProt: A0A4V1C5W1; GenBank: QBZ57765; UniProt: Q2KEW0; GenBank: EAQ71519,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ER-derived vesicles protein ERV14,,,cAMP and moPmk1-MAPK signaling pathway,loss of pathogenicity,,,,,no lesion,reduced,,reduced,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,ΔMoerv14 mutants failed to produce any leaf lesions.,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21683,PHI:123965,UniProt,G4MYQ8,GenBank,EHA55287,,,70-15,Erv14 (MGG_08132),chromosome 2,,,MoPth11; MoWish; MoSho1,UniProt: A0A4V1C5W1; GenBank: QBZ57765; UniProt: Q2KEW0; GenBank: EAQ71519,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ER-derived vesicles protein ERV14,,,cAMP and moPmk1-MAPK signaling pathway,loss of pathogenicity,,,,,no lesion,reduced,,reduced,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,ΔMoerv14 mutants failed to produce any leaf lesions.,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21684,PHI:123965,UniProt,G4MYQ8,GenBank,EHA55287,,,70-15,Erv14 (MGG_08132),chromosome 2,"supplementing cAMP on the ΔMoerv14 mutant; transformed a MoMST7S212D, T216E (MoMST7DE) construct into the ΔMoerv14",,MoPth11; MoWish; MoSho1,UniProt: A0A4V1C5W1; GenBank: QBZ57765; UniProt: Q2KEW0; GenBank: EAQ71519,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ER-derived vesicles protein ERV14,,,cAMP and moPmk1-MAPK signaling pathway,reduced virulence,,,,,no lesion,reduced,,reduced,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,Exogenous cAMP also suppressed the virulence defect of ΔMoerv14 mutant; the virulence of ΔMoerv14/ MoMST7DE was partially restored when compared with the ΔMoerv14 mutant.,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21685,PHI:123965,UniProt,G4MYQ8,GenBank,EHA55287,,,70-15,Erv14 (MGG_08132),chromosome 2,"supplementing cAMP on the ΔMoerv14 mutant; transformed a MoMST7S212D, T216E (MoMST7DE) construct into the ΔMoerv14",,MoPth11; MoWish; MoSho1,UniProt: A0A4V1C5W1; GenBank: QBZ57765; UniProt: Q2KEW0; GenBank: EAQ71519,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ER-derived vesicles protein ERV14,,,cAMP and moPmk1-MAPK signaling pathway,reduced virulence,,,,,no lesion,reduced,,reduced,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,Exogenous cAMP also suppressed the virulence defect of ΔMoerv14 mutant; the virulence of ΔMoerv14/ MoMST7DE was partially restored when compared with the ΔMoerv14 mutant.,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21686,PHI:123966,UniProt,G4MZM1,GenBank,EHA55385,,,70-15,ERV25 (MGG_08210),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ER-derived vesicles protein ERV14,,,,unaffected pathogenicity,,,,,no lesion,,,,wild type,no,,,,,,,gene deletion: full,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,ΔMoerv25 produced numerous spindle-shaped lesions,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21687,PHI:123966,UniProt,G4MZM1,GenBank,EHA55385,,,70-15,ERV25 (MGG_08210),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ER-derived vesicles protein ERV14,,,,unaffected pathogenicity,,,,,no lesion,,,,wild type,no,,,,,,,gene deletion: full,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,ΔMoerv25 produced numerous spindle-shaped lesions,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21688,PHI:123967,UniProt,G4NFV0,GenBank,EHA46907,,,70-15,ERV26 (MGG_08706),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ER-derived vesicles protein ERV14,,,,unaffected pathogenicity,,,,,no lesion,,,,wild type,no,,,,,,,gene deletion: full,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,ΔMoerv26 produced numerous spindle-shaped lesions,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21689,PHI:123967,UniProt,G4NFV0,GenBank,EHA46907,,,70-15,ERV26 (MGG_08706),chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ER-derived vesicles protein ERV14,,,,unaffected pathogenicity,,,,,no lesion,,,,wild type,no,,,,,,,gene deletion: full,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,ΔMoerv26 produced numerous spindle-shaped lesions,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21690,PHI:123968,UniProt,G4NDC9,GenBank,EHA48418,,,70-15,ERV41 (MGG_00949),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ER-derived vesicles protein ERV14,,,,unaffected pathogenicity,,,,,no lesion,,,,wild type,no,,,,,,,gene deletion: full,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,ΔMoerv41 produced numerous spindle-shaped lesions,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21691,PHI:123968,UniProt,G4NDC9,GenBank,EHA48418,,,70-15,ERV41 (MGG_00949),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ER-derived vesicles protein ERV14,,,,unaffected pathogenicity,,,,,no lesion,,,,wild type,no,,,,,,,gene deletion: full,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,ΔMoerv41 produced numerous spindle-shaped lesions,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21692,PHI:123969,UniProt,G4MXL4,GenBank,EHA54345,,,70-15,ERV46 (MGG_01245),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,ER-derived vesicles protein ERV14,,,,unaffected pathogenicity,,,,,no lesion,,,,wild type,no,,,,,,,gene deletion: full,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,ΔMoerv46 produced numerous spindle-shaped lesions,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21693,PHI:123969,UniProt,G4MXL4,GenBank,EHA54345,,,70-15,ERV46 (MGG_01245),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,ER-derived vesicles protein ERV14,,,,unaffected pathogenicity,,,,,no lesion,,,,wild type,no,,,,,,,gene deletion: full,,,NN,37011084,PubMed,10.1371/journal.ppat.1011251,PLoS Pathog. 2023 Apr 3;19(4):e1011251. doi: 10.1371/journal.ppat.1011251. eCollection 2023 Apr,zhgzhang@njau.edu.cn,ΔMoerv46 produced numerous spindle-shaped lesions,B Qian 2023,2023,5 genes,Qian-2023-MoErv14 mediates the intracellular t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21694,PHI:123970,UniProt,A0A1A5HK71,GenBank,AQY23227,,,HXb2,EptA (GE296_RS09715),,,,,,,34085,Riemerella anatipestifer,,RA-LZ01,fibrinous serositis; caseous salpingitis; vegetative disorder,birds,8839,Anas platyrhynchos (related: mallard),,,,brain,lipid A PEA transferases,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37071453,PubMed,10.1096/fj.202300215R,FASEB J. 2023 May;37(5):e22928. doi: 10.1096/fj.202300215R,,"The survival rate of WT RALZ01 and complemented strain cRA-LZ01ΔRaEptA was 18.7% and 57%, respectively, and that of deleted strain RALZ01ΔRaEptA was 100%.",Q Chen 2023,2023,1 gene,Chen-2023-EptA of Riemerella anatipestifer med,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21695,PHI:123971,UniProt,A0A806DCR4,GenBank,ADO80279,,,R2866,copA (HIAG_01772),,,,,,,727,Haemophilus influenzae,656913,NT127,acute respiratory tract infection; chronic respiratory tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37014212,PubMed,10.1128/iai.00091-23,Infect Immun. 2023 May 16;91(5):e0009123. doi: 10.1128/iai.00091-23. Epub 2023 Apr 4,bakerley@umc.edu,Attenuation in virulence was specific to the mutation of copA,S M Wong 2023,2023,2 genes,Wong-2023-Copper Efflux System Required in Mur,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21696,PHI:123971,UniProt,A0A806DCR4,GenBank,ADO80279,,,R2866,copA (HIAG_01772),,,,,,PHI:123972,727,Haemophilus influenzae,656913,NT127,acute respiratory tract infection; chronic respiratory tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,copper-transporting ATPase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37014212,PubMed,10.1128/iai.00091-23,Infect Immun. 2023 May 16;91(5):e0009123. doi: 10.1128/iai.00091-23. Epub 2023 Apr 4,bakerley@umc.edu,Attenuation in virulence was specific to the mutation of copZA.,S M Wong 2023,2023,2 genes,Wong-2023-Copper Efflux System Required in Mur,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21697,PHI:123972,UniProt,A0A2S9SH75,GenBank,PRM83151,,,39P18H1,copZ (HIAG_01773),,,,,,PHI:123971,727,Haemophilus influenzae,656913,NT127,acute respiratory tract infection; chronic respiratory tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,copper chaperone copZ,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37014212,PubMed,10.1128/iai.00091-23,Infect Immun. 2023 May 16;91(5):e0009123. doi: 10.1128/iai.00091-23. Epub 2023 Apr 4,bakerley@umc.edu,Attenuation in virulence was specific to the mutation of copZA.,S M Wong 2023,2023,2 genes,Wong-2023-Copper Efflux System Required in Mur,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21698,PHI:123973,UniProt,A0A0H3MY12,GenBank,CBA60058,,,CD196,RsbW,,,,,,,1496,Clostridioides difficile,645463,R20291,nosocomial diarrhea,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,anti-sigma factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37098979,PubMed,10.1128/jb.00466-22,J Bacteriol. 2023 Apr 26:e0046622. doi: 10.1128/jb.00466-22. Online ahead of print,m.unnikrishnan@warwick.ac.uk,G. mellonella infected with ΔrsbW displayed a higher survival rate at both 24 and 72 h (P = 0.0012) compared to those infected with the WT strain.,J K J Cheng 2023,2023,1 gene,Cheng-2023-Regulatory Role of Anti-Sigma Facto,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21699,PHI:123974,UniProt,D0Z972,GenBank,ACY82946,,,EIB202,TrxA (ETAE_0099),,,,,,,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,serum; spleen; kidney,thioredoxin reductase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37110252,PubMed,10.3390/microorganisms11040827,Microorganisms. 2023 Mar 24;11(4):827. doi: 10.3390/microorganisms11040827,guhanjie@itbb.org.cn,TrxA mutant exhibited remarkably lower survival rate [ΔtrxA (50%)]than the WT.,J He 2023,2023,3 genes,He-2023-The Thioredoxin System in Edwardsiella,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21700,PHI:123975,UniProt,D0ZA23,GenBank,ACY85037,,,EIB202,TrxB (ETAE_2202),,,,,,,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,serum; spleen; kidney,thioredoxin reductase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37110252,PubMed,10.3390/microorganisms11040827,Microorganisms. 2023 Mar 24;11(4):827. doi: 10.3390/microorganisms11040827,guhanjie@itbb.org.cn,TrxB mutant exhibited remarkably lower survival rate [ΔtrxB (27%)]than the WT.,J He 2023,2023,3 genes,He-2023-The Thioredoxin System in Edwardsiella,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21701,PHI:123976,UniProt,D0ZC05,GenBank,ACY83406,,,EIB202,TrxC (ETAE_0559),,,,,,,636,Edwardsiella tarda,,TX01,hemorrhagic septicemia,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,serum; spleen; kidney,thioredoxin reductase,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37110252,PubMed,10.3390/microorganisms11040827,Microorganisms. 2023 Mar 24;11(4):827. doi: 10.3390/microorganisms11040827,guhanjie@itbb.org.cn,TrxC mutant exhibited remarkably lower survival rate [ΔtrxC (50%)]than the WT.,J He 2023,2023,3 genes,He-2023-The Thioredoxin System in Edwardsiella,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21702,PHI:123977,UniProt,Q5WUN1,GenBank,CAH16377,,,Lens,lphD,,,,,,,446,Legionella pneumophila,,,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37059817,PubMed,10.1038/s41467-023-37885-z,Nat Commun. 2023 Apr 14;14(1):2154. doi: 10.1038/s41467-023-37885-z,cbuch@pasteur.fr,The ΔlphD strain showed a consistent growth delay compared to the wild-type strain and virulence.,D Schator 2023,2023,2 genes,Schator-2023-Legionella para-effectors target,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21703,PHI:123978,UniProt,A0A378K3S0,,,,,,romA,,,,,,,446,Legionella pneumophila,,,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37059817,PubMed,10.1038/s41467-023-37885-z,Nat Commun. 2023 Apr 14;14(1):2154. doi: 10.1038/s41467-023-37885-z,cbuch@pasteur.fr,The ΔromA strain showed a consistent growth delay compared to the wild-type strain and virulence.,D Schator 2023,2023,2 genes,Schator-2023-Legionella para-effectors target,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21704,PHI:123977,UniProt,Q5WUN1,GenBank,CAH16377,,,Lens,lphD,,,,,,PHI:123978,446,Legionella pneumophila,,,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37059817,PubMed,10.1038/s41467-023-37885-z,Nat Commun. 2023 Apr 14;14(1):2154. doi: 10.1038/s41467-023-37885-z,cbuch@pasteur.fr,The ΔlphDΔromA strain showed a consistent growth delay compared to the wild-type strain and virulence.,D Schator 2023,2023,2 genes,Schator-2023-Legionella para-effectors target,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21705,PHI:123978,UniProt,A0A378K3S0,,,,,,romA,,,,,,PHI:123977,446,Legionella pneumophila,,,Legionnaires' disease,eukaryotes,5755,Acanthamoeba castellanii (no common name found),,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37059817,PubMed,10.1038/s41467-023-37885-z,Nat Commun. 2023 Apr 14;14(1):2154. doi: 10.1038/s41467-023-37885-z,cbuch@pasteur.fr,The ΔlphDΔromA strain showed a consistent growth delay compared to the wild-type strain and virulence.,D Schator 2023,2023,2 genes,Schator-2023-Legionella para-effectors target,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21706,PHI:123977,UniProt,Q5WUN1,GenBank,CAH16377,,,Lens,lphD,,,,,,,446,Legionella pneumophila,,,Legionnaires' disease,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37059817,PubMed,10.1038/s41467-023-37885-z,Nat Commun. 2023 Apr 14;14(1):2154. doi: 10.1038/s41467-023-37885-z,cbuch@pasteur.fr,The ΔlphD strain showed a consistent growth delay compared to the wild-type strain and virulence.,D Schator 2023,2023,2 genes,Schator-2023-Legionella para-effectors target,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21707,PHI:123978,UniProt,A0A378K3S0,,,,,,romA,,,,,,,446,Legionella pneumophila,,,Legionnaires' disease,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37059817,PubMed,10.1038/s41467-023-37885-z,Nat Commun. 2023 Apr 14;14(1):2154. doi: 10.1038/s41467-023-37885-z,cbuch@pasteur.fr,The ΔromA strain showed a consistent growth delay compared to the wild-type strain and virulence.,D Schator 2023,2023,2 genes,Schator-2023-Legionella para-effectors target,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21708,PHI:123977,UniProt,Q5WUN1,GenBank,CAH16377,,,Lens,lphD,,,,,,PHI:123978,446,Legionella pneumophila,,,Legionnaires' disease,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37059817,PubMed,10.1038/s41467-023-37885-z,Nat Commun. 2023 Apr 14;14(1):2154. doi: 10.1038/s41467-023-37885-z,cbuch@pasteur.fr,The ΔlphDΔromA strain showed a consistent growth delay compared to the wild-type strain and virulence.,D Schator 2023,2023,2 genes,Schator-2023-Legionella para-effectors target,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21709,PHI:123978,UniProt,A0A378K3S0,,,,,,romA,,,,,,PHI:123977,446,Legionella pneumophila,,,Legionnaires' disease,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37059817,PubMed,10.1038/s41467-023-37885-z,Nat Commun. 2023 Apr 14;14(1):2154. doi: 10.1038/s41467-023-37885-z,cbuch@pasteur.fr,The ΔlphDΔromA strain showed a consistent growth delay compared to the wild-type strain and virulence.,D Schator 2023,2023,2 genes,Schator-2023-Legionella para-effectors target,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21710,PHI:123979,UniProt,A0A8E5HNC0,GenBank,QUC18463,,,,ATG6 (UV8b_02704),chromosome 2,,,UvBI-1; UvBI-1b,,,1159556,Ustilaginoidea virens,,JS60-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,autophagy-related protein 6,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37102873,PubMed,10.1128/spectrum.04898-22,Microbiol Spectr. 2023 Apr 27:e0489822. doi: 10.1128/spectrum.04898-22. Online ahead of print,wxyin@mail.hzau.edu.cn,"UvATG6 mutants produced a few smut balls in rice, in contrast to the typical and many false smut balls of the wild-type and complemented strains.",L Gu 2023,2023,3 genes,Gu-2023-UvATG6 Interacts with BAX Inhibitor 1,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21711,PHI:123980,UniProt,A0A8E5HLT2,,,,,,BI-1b,,,,,,,1159556,Ustilaginoidea virens,,JZ11-28,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,BAX inhibitor 1,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37102873,PubMed,10.1128/spectrum.04898-22,Microbiol Spectr. 2023 Apr 27:e0489822. doi: 10.1128/spectrum.04898-22. Online ahead of print,wxyin@mail.hzau.edu.cn,UvBI-1b mutant exhibited fewer smut balls indicating reduced virulence.,L Gu 2023,2023,3 genes,Gu-2023-UvATG6 Interacts with BAX Inhibitor 1,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21712,PHI:123981,UniProt,A0A8E5HLT2,GenBank,QUC17648,,,,BI-1,chromosome 2,,,,,PHI:123980,1159556,Ustilaginoidea virens,,JZ11-28,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,BAX inhibitor 1,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,37102873,PubMed,10.1128/spectrum.04898-22,Microbiol Spectr. 2023 Apr 27:e0489822. doi: 10.1128/spectrum.04898-22. Online ahead of print,wxyin@mail.hzau.edu.cn,Double mutant exhibited fewer smut balls indicating reduced virulence.,L Gu 2023,2023,3 genes,Gu-2023-UvATG6 Interacts with BAX Inhibitor 1,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21713,PHI:123980,UniProt,A0A8E5HLT2,,,,,,BI-1b,,,,,,PHI:123981,1159556,Ustilaginoidea virens,,JZ11-28,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,BAX inhibitor 1,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,37102873,PubMed,10.1128/spectrum.04898-22,Microbiol Spectr. 2023 Apr 27:e0489822. doi: 10.1128/spectrum.04898-22. Online ahead of print,wxyin@mail.hzau.edu.cn,Double mutant exhibited fewer smut balls indicating reduced virulence.,L Gu 2023,2023,3 genes,Gu-2023-UvATG6 Interacts with BAX Inhibitor 1,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21714,PHI:123982,UniProt,Q04MC1,GenBank,ABJ54480,,,D39,SPD_0310,,,,,,,1313,Streptococcus pneumoniae,373153,D39,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,UPF0371 protein SPD_0310,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35414267,PubMed,10.1128/msystems.00221-22,mSystems. 2022 Jun 28;7(3):e0022122. doi: 10.1128/msystems.00221-22. Epub 2022 Apr 13,tsunxs@jnu.edu.cn,Δspd_0310 strain has a lower virulence than the wild type.,K Cao 2022,2022,1 gene,Cao-2022-Identification and Tetramer Structure,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21715,PHI:123983,UniProt,G4NEF1,GenBank,EHA49428,,,70-15,Def1 (MGG_00124),chromosome 5,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,RNA polymerase II degradation factor 1,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37108921,PubMed,10.3390/jof9040467,J Fungi (Basel). 2023 Apr 13;9(4):467. doi: 10.3390/jof9040467,chenxiaolin@mail.hzau.edu.cn,"""Numerous typical lesions appeared on the leaves inoculated with the wild type and complementary strains, while fewer and smaller lesions appeared on the leaves inoculated with Δdef1 mutants.""",X Zhang 2023,2023,1 gene,Zhang-2023-RNAPII Degradation Factor Def1 Is R,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21716,PHI:123983,UniProt,G4NEF1,GenBank,EHA49428,,,70-15,Def1 (MGG_00124),chromosome 5,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,RNA polymerase II degradation factor 1,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37108921,PubMed,10.3390/jof9040467,J Fungi (Basel). 2023 Apr 13;9(4):467. doi: 10.3390/jof9040467,chenxiaolin@mail.hzau.edu.cn,"""Numerous typical lesions appeared on the leaves inoculated with the wild type and complementary strains, while fewer and smaller lesions appeared on the leaves inoculated with Δdef1 mutants.""",X Zhang 2023,2023,1 gene,Zhang-2023-RNAPII Degradation Factor Def1 Is R,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21717,PHI:123983,UniProt,G4NEF1,GenBank,EHA49428,,,70-15,Def1 (MGG_00124),chromosome 5,O-GlcNAcylation at Ser232,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,RNA polymerase II degradation factor 1,,,,reduced virulence,,,,,smaller lesions,wild type,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,37108921,PubMed,10.3390/jof9040467,J Fungi (Basel). 2023 Apr 13;9(4):467. doi: 10.3390/jof9040467,chenxiaolin@mail.hzau.edu.cn,"Area of lesions caused by Δdef1/DEF1S232A were significantly decreased compared to the wild type and complementary strains, but still slightly increased compared to Ddef1.",X Zhang 2023,2023,1 gene,Zhang-2023-RNAPII Degradation Factor Def1 Is R,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21718,PHI:123983,UniProt,G4NEF1,GenBank,EHA49428,,,70-15,Def1 (MGG_00124),chromosome 5,O-GlcNAcylation at Ser232,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,RNA polymerase II degradation factor 1,,,,reduced virulence,,,,,smaller lesions,wild type,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,37108921,PubMed,10.3390/jof9040467,J Fungi (Basel). 2023 Apr 13;9(4):467. doi: 10.3390/jof9040467,chenxiaolin@mail.hzau.edu.cn,"Area of lesions caused by Δdef1/DEF1S232A were significantly decreased compared to the wild type and complementary strains, but still slightly increased compared to Ddef1.",X Zhang 2023,2023,1 gene,Zhang-2023-RNAPII Degradation Factor Def1 Is R,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21719,PHI:123984,UniProt,I1RZR4,GenBank,HG970332,,,PH-1,fgpld1,chromosome 1,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,lipase-encoding genes,,,,reduced virulence,,,,,,reduced,defective,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37093014,PubMed,10.1128/spectrum.05285-22,Microbiol Spectr. 2023 Apr 24:e0528522. doi: 10.1128/spectrum.05285-22. Online ahead of print,hogongi7@snu.ac.kr.,"fgpld1 showed reduced mycelial growth, defective in perithecial maturation and showed defects in virulence.",S Kim 2023,2023,6 genes,Kim-2023-Genetic and Transcriptional Regulator,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21720,PHI:123985,UniProt,I1RV75,GenBank,CEF76407,,,PH-1,fg08139,chromosome 2,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,lipase-encoding genes,,,,unaffected pathogenicity,,,,,,,defective,wild type,,no,,,,,,,gene deletion: full,,,NN,37093014,PubMed,10.1128/spectrum.05285-22,Microbiol Spectr. 2023 Apr 24:e0528522. doi: 10.1128/spectrum.05285-22. Online ahead of print,hogongi7@snu.ac.kr.,fg08139 showed defective in perithecial maturation and did not show defects in virulence.,S Kim 2023,2023,6 genes,Kim-2023-Genetic and Transcriptional Regulator,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21721,PHI:123986,UniProt,I1RMU7,GenBank,CEF87225,,,PH-1,fg05297,chromosome 3,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,lipase-encoding genes,,,,unaffected pathogenicity,,,,,,,defective,wild type,,no,,,,,,,gene deletion: full,,,NN,37093014,PubMed,10.1128/spectrum.05285-22,Microbiol Spectr. 2023 Apr 24:e0528522. doi: 10.1128/spectrum.05285-22. Online ahead of print,hogongi7@snu.ac.kr.,fg05297 showed defective in perithecial maturation and did not show defects in virulence.,S Kim 2023,2023,6 genes,Kim-2023-Genetic and Transcriptional Regulator,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21722,PHI:123987,,no data found,,,,,,fg12678,,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,lipase-encoding genes,,,,unaffected pathogenicity,,,,,,,defective,wild type,,no,,,,,,,gene deletion: full,,,NN,37093014,PubMed,10.1128/spectrum.05285-22,Microbiol Spectr. 2023 Apr 24:e0528522. doi: 10.1128/spectrum.05285-22. Online ahead of print,hogongi7@snu.ac.kr.,fg12678 showed defective in perithecial maturation and did not show defects in virulence.,S Kim 2023,2023,6 genes,Kim-2023-Genetic and Transcriptional Regulator,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21723,PHI:123988,UniProt,I1RT73,GenBank,CEF85302,,,PH-1,fg07372,chromosome 4,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,lipase-encoding genes,,,,unaffected pathogenicity,,,,,,,defective,increased,,no,,,,,,,gene deletion: full,,,NN,37093014,PubMed,10.1128/spectrum.05285-22,Microbiol Spectr. 2023 Apr 24:e0528522. doi: 10.1128/spectrum.05285-22. Online ahead of print,hogongi7@snu.ac.kr.,fg07372 showed defective in perithecial maturation and did not show defects in virulence.,S Kim 2023,2023,6 genes,Kim-2023-Genetic and Transcriptional Regulator,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21724,PHI:123989,,no data found,,,,,,fg00208,,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spikelet,lipase-encoding genes,,,,unaffected pathogenicity,,,,,,,defective,wild type,,no,,,,,,,gene deletion: full,,,NN,37093014,PubMed,10.1128/spectrum.05285-22,Microbiol Spectr. 2023 Apr 24:e0528522. doi: 10.1128/spectrum.05285-22. Online ahead of print,hogongi7@snu.ac.kr.,fg00208 showed defective in perithecial maturation and did not show defects in virulence.,S Kim 2023,2023,6 genes,Kim-2023-Genetic and Transcriptional Regulator,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21725,PHI:123990,,no data found,,,,,,Trx1 (VEDA_00080),,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,seedling; root,thioredoxins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37065139,PubMed,10.3389/fmicb.2023.1130468,Front Microbiol. 2023 Mar 31;14:1130468. doi: 10.3389/fmicb.2023.1130468. eCollection 2023,zhangdandan@caas.cn,"Deletion of VdTrx1 resulted in higher intracellular ROS levels of V. dahliae mycelium, displayed impaired conidial production, and showed significantly reduced virulence on Gossypium hirsutum.",L Tian 2023,2023,1 gene,"Tian-2023-Thioredoxin VdTrx1, an unconventiona",BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21726,PHI:123990,,no data found,,,,,,Trx1 (VEDA_00080),,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-1,,,seedling,thioredoxins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37065139,PubMed,10.3389/fmicb.2023.1130468,Front Microbiol. 2023 Mar 31;14:1130468. doi: 10.3389/fmicb.2023.1130468. eCollection 2023,zhangdandan@caas.cn,"Deletion of VdTrx1 resulted in higher intracellular ROS levels of V. dahliae mycelium, displayed impaired conidial production, and showed significantly reduced virulence on A. thaliana.",L Tian 2023,2023,1 gene,"Tian-2023-Thioredoxin VdTrx1, an unconventiona",BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21727,PHI:123990,,no data found,,,,,,Trx1 (VEDA_00080),,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling,thioredoxins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37065139,PubMed,10.3389/fmicb.2023.1130468,Front Microbiol. 2023 Mar 31;14:1130468. doi: 10.3389/fmicb.2023.1130468. eCollection 2023,zhangdandan@caas.cn,"Deletion of VdTrx1 resulted in higher intracellular ROS levels of V. dahliae mycelium, displayed impaired conidial production, and showed significantly reduced virulence on N. benthamiana.",L Tian 2023,2023,1 gene,"Tian-2023-Thioredoxin VdTrx1, an unconventiona",BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21728,PHI:123991,UniProt,W9ZNB6,GenBank,EXK33324,,,26406,YjeF,chromosome unknown,,,,,,5507,Fusarium oxysporum,59765,f. sp. momordicae strain SD-1,Fusarium wilt,eudicots,3673,Momordica charantia (related: Bitter melon),,,,plant; leaf,NAD(P)H-hydrate epimerase,,,,increased virulence (hypervirulence),,,,,,increased,,increased,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37108422,PubMed,10.3390/ijms24087260,Int J Mol Sci. 2023 Apr 14;24(8):7260. doi: 10.3390/ijms24087260,zhaoying@henau.edu.cn,YjeF caused a significant increase in virulence in bitter gourd plants with a higher disease severity index and enhanced the accumulation of glutathione peroxidase and the ability to degrade hydrogen peroxide in F. oxysporum.,C Wei 2023,2023,1 gene,Wei-2023-The FomYjeF Protein Influences the Sp,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21729,PHI:123992,UniProt,A7F1E3,GenBank,EDN95535,,,1980,GSR1 (SS1G_11413),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,glycine-and serine-rich protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37140432,PubMed,10.1128/spectrum.00986-23,Microbiol Spectr. 2023 May 4:e0098623. doi: 10.1128/spectrum.00986-23. Online ahead of print,zbyuyang@swu.edu.cn,Deletion of SsGSR1 leads to impaired cell wall integrity of hyphae and showed impaired virulence.,Y Hu 2023,2023,1 gene,Hu-2023-Variable Tandem Glycine-Rich Repeats C,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21730,PHI:123992,UniProt,A7F1E3,GenBank,EDN95535,,,1980,GSR1 (SS1G_11413),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),,,,leaf,glycine-and serine-rich protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37140432,PubMed,10.1128/spectrum.00986-23,Microbiol Spectr. 2023 May 4:e0098623. doi: 10.1128/spectrum.00986-23. Online ahead of print,zbyuyang@swu.edu.cn,Deletion of SsGSR1 leads to impaired cell wall integrity of hyphae and showed impaired virulence.,Y Hu 2023,2023,1 gene,Hu-2023-Variable Tandem Glycine-Rich Repeats C,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21731,PHI:123992,UniProt,A7F1E3,GenBank,EDN95535,,,1980,GSR1 (SS1G_11413),,,,,,,5180,Sclerotinia sclerotiorum,,TL-18,white mold,eudicots,3708,Brassica napus (related: rape),,,,leaf,glycine-and serine-rich protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37140432,PubMed,10.1128/spectrum.00986-23,Microbiol Spectr. 2023 May 4:e0098623. doi: 10.1128/spectrum.00986-23. Online ahead of print,zbyuyang@swu.edu.cn,Deletion of SsGSR1-2 leads to impaired cell wall integrity of hyphae and displayed virulence similar to that of the wild-type strain.,Y Hu 2023,2023,1 gene,Hu-2023-Variable Tandem Glycine-Rich Repeats C,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21732,PHI:123992,UniProt,A7F1E3,GenBank,EDN95535,,,1980,GSR1 (SS1G_11413),,,,,,,5180,Sclerotinia sclerotiorum,,TL-18,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,glycine-and serine-rich protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37140432,PubMed,10.1128/spectrum.00986-23,Microbiol Spectr. 2023 May 4:e0098623. doi: 10.1128/spectrum.00986-23. Online ahead of print,zbyuyang@swu.edu.cn,Deletion of SsGSR1-2 leads to impaired cell wall integrity of hyphae and displayed virulence similar to that of the wild-type strain.,Y Hu 2023,2023,1 gene,Hu-2023-Variable Tandem Glycine-Rich Repeats C,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21733,PHI:123993,UniProt,Q4WF31,GenBank,EAL86646,,,Af293,mirB (AFUA_3G03640/AFUB_044500),chromosome 3,,,,,,746128,Aspergillus fumigatus,,A1160,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,MFS siderochrome iron transporter B,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36125294,PubMed,10.1128/mbio.02192-22,mBio. 2022 Oct 26;13(5):e0219222. doi: 10.1128/mbio.02192-22. Epub 2022 Sep 20,hubertus.haas@i-med.ac.at,"ΔmirB strain showed significantly reduced virulence (P , 0.001) in infected mice, with a survival rate of 90%, even at 21 days postinfection.",M Aguiar 2022,2022,2 genes,Aguiar-2022-Uptake of the Siderophore Triacety,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21734,PHI:123994,UniProt,Q4WF51,GenBank,EAL86626,,,Af293,mirD [AFUA_3G03440/AFUB_044810]),chromosome 3,,,,,,746128,Aspergillus fumigatus,,A1160,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,MFS siderochrome iron transporter B,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36125294,PubMed,10.1128/mbio.02192-22,mBio. 2022 Oct 26;13(5):e0219222. doi: 10.1128/mbio.02192-22. Epub 2022 Sep 20,hubertus.haas@i-med.ac.at,ΔmirD mutant strains displayed similar high mortality rates of 70 to 100% within 7 days postinfection,M Aguiar 2022,2022,2 genes,Aguiar-2022-Uptake of the Siderophore Triacety,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21735,PHI:123995,,no data found,,,,,,TrxA (SSU05_0237),,,,,,,1307,Streptococcus suis,,serotype 2 strain ZJ081101,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,liver; kidney; spleen; brain,thioredoxin,,,,reduced virulence,,,,,,,,reduced,,,,,,,,,gene deletion: full ; gene complementation,,,NN,37010796,PubMed,10.1007/s12275-023-00038-4,J Microbiol. 2023 Apr;61(4):433-448. doi: 10.1007/s12275-023-00038-4. Epub 2023 Apr 3,tangyulong@isa.ac.cn,70% of mice in the wild type group died and only one out of 10 mice challenged with the ΔTrxA strain died at day 4.,C Zhao 2023,2023,1 gene,Zhao-2023-Thioredoxin A of Streptococcus suis,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21736,PHI:123996,,no data found,,,,,,rli106,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,liver; spleen; kidney,small non-coding RNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37008770,PubMed,10.2478/jvetres-2023-0013,J Vet Res. 2023 Mar 17;67(1):67-77. doi: 10.2478/jvetres-2023-0013. eCollection 2023 Mar,qj710625@shzu.edu.cn,"The biofilm formation, cell adhesion, invasion, intracellular proliferation and pathogenicity of LM-Δrli106 in mice were significantly reduced.",Y Guo 2023,2023,1 gene,Guo-2023-The Small Non-coding RNA rli106 Contr,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21737,PHI:123997,UniProt,J9VV33,GenBank,AFR98118,,,H99,pho80 (CNAG_01922),chromosome 11,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,phosphate acquisition kinase,,,phosphate acquisition (PHO) pathway,reduced virulence,,,,,,,,reduced,,,,,,,,,gene deletion: full ; gene complementation,,,NN,37017534,PubMed,10.1128/mbio.03551-22,mBio. 2023 Apr 25;14(2):e0355122. doi: 10.1128/mbio.03551-22. Epub 2023 Apr 5,julianne.djordjevic@sydney.edu.au,"pho80D-infected mice were shown to survive longer than WT-infected mice, with a difference in median survival of approximately 6 days.",B G Bowring 2023,2023,2 genes,Bowring-2023-Dysregulating PHO Signaling via t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21738,PHI:123998,UniProt,J9VLD1,GenBank,AFR95292,,,H99,pho81 (CNAG_02541),chromosome 6,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,cyclin-dependent protein kinase inhibitor,,,phosphate acquisition (PHO) pathway,loss of pathogenicity,,,,,,,,reduced,,,,,,,,,gene deletion: full ; gene complementation,,,NN,37017534,PubMed,10.1128/mbio.03551-22,mBio. 2023 Apr 25;14(2):e0355122. doi: 10.1128/mbio.03551-22. Epub 2023 Apr 5,julianne.djordjevic@sydney.edu.au,"pho81D is avirulent, with no pho81D-infected mice experiencing symptoms of infection or weight loss and all pho81D 1 PHO81-infected mice succumbing to infection at the same time as the WT-infected mice.",B G Bowring 2023,2023,2 genes,Bowring-2023-Dysregulating PHO Signaling via t,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21739,PHI:123999,UniProt,D2TU76,GenBank,CBG90542,,,ICC168,cpxR,,,,,,PHI:124000,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ; C57BL/6J,,,spleen,two-component system,,,,loss of pathogenicity,,,,,,,,reduced ; defective,,no,,,,,,,gene deletion: full,,,NN,36000875,PubMed,10.1128/iai.00314-22,Infect Immun. 2022 Sep 15;90(9):e0031422. doi: 10.1128/iai.00314-22. Epub 2022 Aug 24,traivio@ualberta.ca,ΔcpxRA mutant had reduced colonization and attenuated virulence.,A Gilliland 2022,2022,6 genes,Gilliland-2022-Simulated Colonic Fluid Replica,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21740,PHI:124000,UniProt,D2TU77,GenBank,CBG90543,,,ICC168,cpxA,,,,,,PHI:123999,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ; C57BL/6J,,,spleen,two-component system,,,,loss of pathogenicity,,,,,,,,reduced ; defective,,no,,,,,,,gene deletion: full,,,NN,36000875,PubMed,10.1128/iai.00314-22,Infect Immun. 2022 Sep 15;90(9):e0031422. doi: 10.1128/iai.00314-22. Epub 2022 Aug 24,traivio@ualberta.ca,ΔcpxRA mutant had reduced colonization and attenuated virulence.,A Gilliland 2022,2022,6 genes,Gilliland-2022-Simulated Colonic Fluid Replica,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21741,PHI:124001,UniProt,D2TMT4,GenBank,CBG88640,,,ICC168,yebE,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ; C57BL/6J,,,spleen,cpx-regulated gene,,,,unaffected pathogenicity,,,,,,,,defective,,no,,,,,,,gene deletion: full,,,NN,36000875,PubMed,10.1128/iai.00314-22,Infect Immun. 2022 Sep 15;90(9):e0031422. doi: 10.1128/iai.00314-22. Epub 2022 Aug 24,traivio@ualberta.ca,Cpx-regulated gene mutants exhibited marked virulence phenotypes,A Gilliland 2022,2022,6 genes,Gilliland-2022-Simulated Colonic Fluid Replica,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21742,PHI:124002,UniProt,D2TM47,GenBank,CBG88624,,,ICC168,yebE,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ; C57BL/6J,,,spleen,cpx-regulated gene,,,,unaffected pathogenicity,,,,,,,,defective,,no,,,,,,,gene deletion: full,,,NN,36000875,PubMed,10.1128/iai.00314-22,Infect Immun. 2022 Sep 15;90(9):e0031422. doi: 10.1128/iai.00314-22. Epub 2022 Aug 24,traivio@ualberta.ca,Cpx-regulated gene mutants exhibited marked virulence phenotypes,A Gilliland 2022,2022,6 genes,Gilliland-2022-Simulated Colonic Fluid Replica,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21743,PHI:124003,UniProt,D2TRN3,GenBank,CBG90293,,,ICC168,ygiB,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ; C57BL/6J,,,spleen,cpx-regulated gene,,,,unaffected pathogenicity,,,,,,,,defective,,no,,,,,,,gene deletion: full,,,NN,36000875,PubMed,10.1128/iai.00314-22,Infect Immun. 2022 Sep 15;90(9):e0031422. doi: 10.1128/iai.00314-22. Epub 2022 Aug 24,traivio@ualberta.ca,Cpx-regulated gene mutants exhibited marked virulence phenotypes,A Gilliland 2022,2022,6 genes,Gilliland-2022-Simulated Colonic Fluid Replica,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21744,PHI:124004,UniProt,D2TQF0,GenBank,CBG87616,,,ICC168,bssR,,,,,,,67825,Citrobacter rodentium,,DBS100,colitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ; C57BL/6J,,,spleen,cpx-regulated gene,,,,unaffected pathogenicity,,,,,,,,defective,,no,,,,,,,gene deletion: full,,,NN,36000875,PubMed,10.1128/iai.00314-22,Infect Immun. 2022 Sep 15;90(9):e0031422. doi: 10.1128/iai.00314-22. Epub 2022 Aug 24,traivio@ualberta.ca,Cpx-regulated gene mutants exhibited marked virulence phenotypes,A Gilliland 2022,2022,6 genes,Gilliland-2022-Simulated Colonic Fluid Replica,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21745,PHI:124005,UniProt,A0A384JRC2,GenBank,ATZ52914,,,B05.10,Taf14 (Bcin08g05310),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3879,Medicago sativa (related: alfalfa),,,,leaf,TATA box-binding protein (TBP)-associated factor 14,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37026690,PubMed,10.1111/mpp.13331,Mol Plant Pathol. 2023 Apr 7. doi: 10.1111/mpp.13331. Online ahead of print,wliang1@qau.edu.cn,"The BcTaf14 deletion strain (ΔBcTaf14) showed pleiotropic defects, including slow growth, abnormal colony morphology, reduced conidiation, abnormal conidial morphology, reduced virulence, and altered responses to various stresses.",H Han 2023,2023,1 gene,Han-2023-BcTaf14 regulates growth and developm,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21746,PHI:124005,UniProt,A0A384JRC2,GenBank,ATZ52914,,,B05.10,Taf14 (Bcin08g05310),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3659,Cucumis sativus (related: cucumber),,,,leaf,TATA box-binding protein (TBP)-associated factor 14,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37026690,PubMed,10.1111/mpp.13331,Mol Plant Pathol. 2023 Apr 7. doi: 10.1111/mpp.13331. Online ahead of print,wliang1@qau.edu.cn,"The BcTaf14 deletion strain (ΔBcTaf14) showed pleiotropic defects, including slow growth, abnormal colony morphology, reduced conidiation, abnormal conidial morphology, reduced virulence, and altered responses to various stresses.",H Han 2023,2023,1 gene,Han-2023-BcTaf14 regulates growth and developm,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21747,PHI:124005,UniProt,A0A384JRC2,GenBank,ATZ52914,,,B05.10,Taf14 (Bcin08g05310),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,TATA box-binding protein (TBP)-associated factor 14,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37026690,PubMed,10.1111/mpp.13331,Mol Plant Pathol. 2023 Apr 7. doi: 10.1111/mpp.13331. Online ahead of print,wliang1@qau.edu.cn,"The BcTaf14 deletion strain (ΔBcTaf14) showed pleiotropic defects, including slow growth, abnormal colony morphology, reduced conidiation, abnormal conidial morphology, reduced virulence, and altered responses to various stresses.",H Han 2023,2023,1 gene,Han-2023-BcTaf14 regulates growth and developm,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21748,PHI:124005,UniProt,A0A384JRC2,GenBank,ATZ52914,,,B05.10,Taf14 (Bcin08g05310),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,TATA box-binding protein (TBP)-associated factor 14,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37026690,PubMed,10.1111/mpp.13331,Mol Plant Pathol. 2023 Apr 7. doi: 10.1111/mpp.13331. Online ahead of print,wliang1@qau.edu.cn,"The BcTaf14 deletion strain (ΔBcTaf14) showed pleiotropic defects, including slow growth, abnormal colony morphology, reduced conidiation, abnormal conidial morphology, reduced virulence, and altered responses to various stresses.",H Han 2023,2023,1 gene,Han-2023-BcTaf14 regulates growth and developm,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21749,PHI:124005,UniProt,A0A384JRC2,GenBank,ATZ52914,,,B05.10,Taf14 (Bcin08g05310),chromosome BCIN08,The mutant BcTaf14G80LW81A ( leucine and alanine mutation) was fused with GFP and then transferred into the ΔBcTaf14 genome to generate ΔBcTaf14-MC strain,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,TATA box-binding protein (TBP)-associated factor 14,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene mutation,,,NN,37026690,PubMed,10.1111/mpp.13331,Mol Plant Pathol. 2023 Apr 7. doi: 10.1111/mpp.13331. Online ahead of print,wliang1@qau.edu.cn,"The virulence of the ΔBcTaf14-MC strains to N. benthamiana leaves was the same as that of the ΔBcTaf14 strain, but significantly reduced compared to that of B05.10.",H Han 2023,2023,1 gene,Han-2023-BcTaf14 regulates growth and developm,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21750,PHI:124005,UniProt,A0A384JRC2,GenBank,ATZ52914,,,B05.10,Taf14 (Bcin08g05310),chromosome BCIN08,ΔBcTaf14-NC strain: N-terminal region (from amino acid residue 1 to 162) of BcTaf14 was fused with GFP and then transferred into the ΔBcTaf14.,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,TATA box-binding protein (TBP)-associated factor 14,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene mutation,,,NN,37026690,PubMed,10.1111/mpp.13331,Mol Plant Pathol. 2023 Apr 7. doi: 10.1111/mpp.13331. Online ahead of print,wliang1@qau.edu.cn,"N. benthamiana leaves with mycelial plugs, the lesions caused by the ΔBcTaf14-NC strains were smaller than those caused by B05.10 and very similar to those caused by the ΔBcTaf14 strain.",H Han 2023,2023,1 gene,Han-2023-BcTaf14 regulates growth and developm,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21751,PHI:124006,UniProt,A0A0J9UDF4,GenBank,KNA96867,,,4287,PUF1 (FOXG_01859),chromosome 5,,,FonARC18,UniProt: A0A8J5U4R2; GenBank: KAG7421578,,5507,Fusarium oxysporum,61366,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Zaojia,,,root; stem; plant,RNA binding pumilio protein,,,rRNA metabolic pathway,reduced virulence,,,,,,reduced,,reduced,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36856417,PubMed,10.1128/mbio.00157-23,mBio. 2023 Apr 25;14(2):e0015723. doi: 10.1128/mbio.00157-23. Epub 2023 Mar 1,dyli@zju.edu.cn,ΔFonPUF1-inoculated plants showed mild disease symptoms and a significantly lower disease severity index compared to WT-inoculated plants at 21 days postinoculation.,Y Gao 2023,2023,8 genes,Gao-2023-Fusarium oxysporum f. sp. niveum Pumi,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21752,PHI:124007,UniProt,A0A0J9UFH3,GenBank,KNA97592,,,4287,PUF2 (FOXG_02224),chromosome 5,,,,,,5507,Fusarium oxysporum,61366,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Zaojia,,,root; stem; plant,RNA binding pumilio protein,,,rRNA metabolic pathway,reduced virulence,,,,,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36856417,PubMed,10.1128/mbio.00157-23,mBio. 2023 Apr 25;14(2):e0015723. doi: 10.1128/mbio.00157-23. Epub 2023 Mar 1,dyli@zju.edu.cn,ΔFonPUF2 and WT-inoculated plants exhibited comparable disease symptoms.,Y Gao 2023,2023,8 genes,Gao-2023-Fusarium oxysporum f. sp. niveum Pumi,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21753,PHI:124008,UniProt,A0A0J9V4R1,GenBank,KNB05836,,,4287,PUF3 (FOXG_07983),chromosome 4,,,,,,5507,Fusarium oxysporum,61366,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Zaojia,,,root; stem; plant,RNA binding pumilio protein,,,rRNA metabolic pathway,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36856417,PubMed,10.1128/mbio.00157-23,mBio. 2023 Apr 25;14(2):e0015723. doi: 10.1128/mbio.00157-23. Epub 2023 Mar 1,dyli@zju.edu.cn,ΔFonPUF3 and WT-inoculated plants exhibited comparable disease symptoms.,Y Gao 2023,2023,8 genes,Gao-2023-Fusarium oxysporum f. sp. niveum Pumi,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21754,PHI:124009,UniProt,A0A0J9WGH7,GenBank,KNA95051,,,4287,PUF4 (FOXG_00799),chromosome 1,,,,,,5507,Fusarium oxysporum,61366,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Zaojia,,,root; stem; plant,RNA binding pumilio protein,,,rRNA metabolic pathway,reduced virulence,,,,,,wild type,,reduced,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36856417,PubMed,10.1128/mbio.00157-23,mBio. 2023 Apr 25;14(2):e0015723. doi: 10.1128/mbio.00157-23. Epub 2023 Mar 1,dyli@zju.edu.cn,ΔFonPUF4 and WT-inoculated plants exhibited comparable disease symptoms.,Y Gao 2023,2023,8 genes,Gao-2023-Fusarium oxysporum f. sp. niveum Pumi,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21755,PHI:124010,UniProt,A0A0D2XCZ5,GenBank,KNA96700,,,4287,PUF5-Ri (FOXG_01770),chromosome 5,,,,,,5507,Fusarium oxysporum,61366,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Zaojia,,,root; stem; plant,RNA binding pumilio protein,,,rRNA metabolic pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36856417,PubMed,10.1128/mbio.00157-23,mBio. 2023 Apr 25;14(2):e0015723. doi: 10.1128/mbio.00157-23. Epub 2023 Mar 1,dyli@zju.edu.cn,ΔFonPUF5-Ri and WT-inoculated plants exhibited comparable disease symptoms.,Y Gao 2023,2023,8 genes,Gao-2023-Fusarium oxysporum f. sp. niveum Pumi,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21756,PHI:124011,UniProt,A0A0D2X8Q2,GenBank,KNA94033,,,4287,PUF6 ( FOXG_00261),chromosome 1,,,,,,5507,Fusarium oxysporum,61366,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Zaojia,,,root; stem; plant,RNA binding pumilio protein,,,rRNA metabolic pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36856417,PubMed,10.1128/mbio.00157-23,mBio. 2023 Apr 25;14(2):e0015723. doi: 10.1128/mbio.00157-23. Epub 2023 Mar 1,dyli@zju.edu.cn,ΔFonPUF6 and WT-inoculated plants exhibited comparable disease symptoms.,Y Gao 2023,2023,8 genes,Gao-2023-Fusarium oxysporum f. sp. niveum Pumi,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21757,PHI:124012,UniProt,A0A8J5U4R2,GenBank,KAG7421578,,,Tf1208,ARC18,,,,,,,5507,Fusarium oxysporum,61366,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Zaojia,,,plant,actin-related protein 2/3 complex,,,rRNA metabolic pathway,reduced virulence,,,,,,wild type,,wild type,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36856417,PubMed,10.1128/mbio.00157-23,mBio. 2023 Apr 25;14(2):e0015723. doi: 10.1128/mbio.00157-23. Epub 2023 Mar 1,dyli@zju.edu.cn,"Pathogenicity test revealed that ΔFonARC18 showed reduced virulence on watermelon, showing a 27% reduction in the disease index compared with WT.",Y Gao 2023,2023,8 genes,Gao-2023-Fusarium oxysporum f. sp. niveum Pumi,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21758,PHI:124013,UniProt,A0A0D2Y922,,,,,,ARP3,,,,,,,5507,Fusarium oxysporum,61366,f. sp. niveum race 1 strain ZJ1,Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Zaojia,,,plant,actin-related protein 2/3 complex,,,rRNA metabolic pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,36856417,PubMed,10.1128/mbio.00157-23,mBio. 2023 Apr 25;14(2):e0015723. doi: 10.1128/mbio.00157-23. Epub 2023 Mar 1,dyli@zju.edu.cn,Pathogenicity tests revealed that disease severity and index in FonARP3-RNAi-inoculated plants were comparable to those in the WTinoculated plants,Y Gao 2023,2023,8 genes,Gao-2023-Fusarium oxysporum f. sp. niveum Pumi,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21759,PHI:124014,UniProt,A4VT28,GenBank,ABP89267,,,05ZYH33,GrpE,,,,,,,1307,Streptococcus suis,,ATCC 700794,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; spleen; liver; lung,protein grpE,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37005968,PubMed,10.1007/s00203-023-03503-1,Arch Microbiol. 2023 Apr 1;205(4):159. doi: 10.1007/s00203-023-03503-1,wg0381@163.com,"Deletion strain induced milder symptoms and lower bacteremia, as well as comparatively minor organ (brain, spleen, liver, and lung) lesions, in the infected mice.",F Yu 2023,2023,2 genes,Yu-2023-GrpE and ComD contribute to the adhere,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21760,PHI:124015,UniProt,A0A116KQ83,GenBank,CYU50010,,,LSS36,ComD,,,,,,,1307,Streptococcus suis,,ATCC 700794,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,brain; spleen; liver; lung,histidine protein kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37005968,PubMed,10.1007/s00203-023-03503-1,Arch Microbiol. 2023 Apr 1;205(4):159. doi: 10.1007/s00203-023-03503-1,wg0381@163.com,"Deletion strain induced milder symptoms and lower bacteremia, as well as comparatively minor organ (brain, spleen, liver, and lung) lesions, in the infected mice.",F Yu 2023,2023,2 genes,Yu-2023-GrpE and ComD contribute to the adhere,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21761,PHI:124016,UniProt,A0A9P2MPL6,GenBank,WP_004920112,,,,RanQ (GE296_RS02355),,,,,,,34085,Riemerella anatipestifer,,RA-LZ01,fibrinous serositis; caseous salpingitis; vegetative disorder,birds,8839,Anas platyrhynchos (related: mallard),,,,,multidrug efflux SMR transporter,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37110330,PubMed,10.3390/microorganisms11040907,Microorganisms. 2023 Mar 31;11(4):907. doi: 10.3390/microorganisms11040907,chenqiwei@caas.cn,"The survival rate of WT RA-LZ01 and supplementary strain cΔRanQ was 20%, and that of deleted strain ΔRanQ was 25%",H Quan 2023,2023,1 gene,Quan-2023-Functional Characterization of a Nov,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21762,PHI:124017,UniProt,Q2FV99,GenBank,ABD31836,,,NCTC 8325,srt1,,,,,,,1280,Staphylococcus aureus,426430,Newman,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver,serine/ threonine phosphatase,,,stp1/stk1 signalling pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36694285,PubMed,10.1080/21505594.2023.2171641,Virulence. 2023 Dec;14(1):2171641. doi: 10.1080/21505594.2023.2171641,llan@ucas.ac.cn,Δstp1 strain exhibited a significantly decreased colonization of liver compared to that of mice infected with the wildtype Newman indicating that ectopic expression of SrtA can suppress the virulence defect of Δstp1.,F Chen 2023,2023,1 gene,Chen-2023-The enzyme activity of sortase A is,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21763,PHI:124018,,no data found,,,,,,STT3B,,,,,,,4784,Phytophthora capsici,,BYA5,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),cv. Green Peak Ox Horn,,,leaf,oligosaccharyltransferase subunit,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37108663,PubMed,10.3390/ijms24087500,Int J Mol Sci. 2023 Apr 19;24(8):7500. doi: 10.3390/ijms24087500,seedling@cau.edu.cn,"PcSTT3B was involved in pathogenicity, lesion diameters, caused by the PcSTT3B-deleted transformants, were significantly lower than that of the BYA5, B-CK, and CB151 strains.",T Cui 2023,2023,1 gene,Cui-2023-Characterization of PcSTT3B as a Key,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21764,PHI:124019,UniProt,A0A631R7G5,GenBank,EDG7028553,,,PNUSAS010410,GalU,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain S584,salmonellosis,birds,9031,Gallus gallus (related: chicken),SPF,,,embryo,uridine diphosphate–glucose pyrophosphorylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,37021122,PubMed,10.3389/fcimb.2023.1149541,Front Cell Infect Microbiol. 2023 Mar 20;13:1149541. doi: 10.3389/fcimb.2023.1149541. eCollection 2023,fengsx@scau.edu.cn,"S584ΔgalU strain group, the mortality rate of chicken embryos inoculated with 108CFU was 100%, and the ELD50 was 6.8 × 108 CFU compared to wild type ELD50 was 6.8×103 CFU.",L Guo 2023,2023,1 gene,Guo-2023-Contribution of GalU to biofilm forma,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21765,PHI:124019,UniProt,A0A631R7G5,GenBank,EDG7028553,,,PNUSAS010410,GalU,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain S584,salmonellosis,birds,9031,Gallus gallus (related: chicken),,,,,uridine diphosphate–glucose pyrophosphorylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,37021122,PubMed,10.3389/fcimb.2023.1149541,Front Cell Infect Microbiol. 2023 Mar 20;13:1149541. doi: 10.3389/fcimb.2023.1149541. eCollection 2023,fengsx@scau.edu.cn,"LD50 values for S584, S584DgalU, and S584DgalU R strains were 1.7 × 108, 1.4 × 1010, and 2.5 × 109. Tissue type : chicks",L Guo 2023,2023,1 gene,Guo-2023-Contribution of GalU to biofilm forma,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21766,PHI:124019,UniProt,A0A631R7G5,GenBank,EDG7028553,,,PNUSAS010410,GalU,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain S584,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,uridine diphosphate–glucose pyrophosphorylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,37021122,PubMed,10.3389/fcimb.2023.1149541,Front Cell Infect Microbiol. 2023 Mar 20;13:1149541. doi: 10.3389/fcimb.2023.1149541. eCollection 2023,fengsx@scau.edu.cn,"LD50 values for S584, S584DgalU, and S584DgalU R strains were 1.6 × 108, 6.8 × 1010, and 1.9 × 108 CFU.",L Guo 2023,2023,1 gene,Guo-2023-Contribution of GalU to biofilm forma,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21767,PHI:124020,,no data found,,,,,,mleS,,,,,,,1280,Staphylococcus aureus,,BS19,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line; BALB/c,,,skin,NAD1-dependent malolactic enzyme coding gene,,,glycolytic pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,37052483,PubMed,10.1128/spectrum.00909-23,Microbiol Spectr. 2023 Apr 13:e0090923. doi: 10.1128/spectrum.00909-23. Online ahead of print,whuibj@163.com,mleS mutant strain was characterized by significantly reduced survival rate; Reductions in the extant skin lesions were observed in mice with mleSmutant infections compared with those with the wild-type infections.,F Chen 2023,2023,1 gene,Chen-2023-mleS in Staphylococcus aureus Contri,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21768,PHI:124021,,no data found,,,,,,RIT11b (ncS06),,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,sRNA,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37097504,PubMed,10.1007/s00253-023-12530-3,Appl Microbiol Biotechnol. 2023 Jun;107(11):3653-3671. doi: 10.1007/s00253-023-12530-3. Epub 2023 Apr 25,,Infection assays revealed that the overexpression of RIT11b in B. cenocepacia K56-2 attenuated the virulence of this strain in C. elegans infection model.,T Pita 2023,2023,6 genes,Pita-2023-Identification of Burkholderia cenoc,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21769,PHI:124022,,no data found,,,,,,RIT32 (ncS16),,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,sRNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37097504,PubMed,10.1007/s00253-023-12530-3,Appl Microbiol Biotechnol. 2023 Jun;107(11):3653-3671. doi: 10.1007/s00253-023-12530-3. Epub 2023 Apr 25,,No effect in B. cenocepacia virulence in C. elegans infection model was detected when RIT32 was overexpressed.,T Pita 2023,2023,6 genes,Pita-2023-Identification of Burkholderia cenoc,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21770,PHI:124023,,no data found,,,,,,RIT55 (ncS11),,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,sRNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37097504,PubMed,10.1007/s00253-023-12530-3,Appl Microbiol Biotechnol. 2023 Jun;107(11):3653-3671. doi: 10.1007/s00253-023-12530-3. Epub 2023 Apr 25,,No effect in B. cenocepacia virulence in C. elegans infection model was detected when RIT55 was overexpressed.,T Pita 2023,2023,6 genes,Pita-2023-Identification of Burkholderia cenoc,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21771,PHI:124024,,no data found,,,,,,RIT43 (nc5U42),,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,sRNA,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37097504,PubMed,10.1007/s00253-023-12530-3,Appl Microbiol Biotechnol. 2023 Jun;107(11):3653-3671. doi: 10.1007/s00253-023-12530-3. Epub 2023 Apr 25,,An increased virulence of B. cenocepacia was observed when RIT43 was silenced.,T Pita 2023,2023,6 genes,Pita-2023-Identification of Burkholderia cenoc,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21772,PHI:124025,,no data found,,,,,,RIT2a (ncS01),,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,sRNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37097504,PubMed,10.1007/s00253-023-12530-3,Appl Microbiol Biotechnol. 2023 Jun;107(11):3653-3671. doi: 10.1007/s00253-023-12530-3. Epub 2023 Apr 25,,No effect in B. cenocepacia virulence in C. elegans infection model was detected when RIT2a was silenced.,T Pita 2023,2023,6 genes,Pita-2023-Identification of Burkholderia cenoc,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21773,PHI:124026,,no data found,,,,,,RIT98 (ncRI12),,,,,,,95486,Burkholderia cenocepacia,985075,K56-2,cystic fibrosis-like disease,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,,sRNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37097504,PubMed,10.1007/s00253-023-12530-3,Appl Microbiol Biotechnol. 2023 Jun;107(11):3653-3671. doi: 10.1007/s00253-023-12530-3. Epub 2023 Apr 25,,No effect in B. cenocepacia virulence in C. elegans infection model was detected when RIT98 was silenced.,T Pita 2023,2023,6 genes,Pita-2023-Identification of Burkholderia cenoc,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21774,PHI:124027,UniProt,X0L985,GenBank,EXM05395,,,54006,FSE1 (FOIG_03990),chromosome unknown,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense TR4,Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),cv. Brazilian,,,Pseudostem,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37108926,PubMed,10.3390/jof9040472,J Fungi (Basel). 2023 Apr 14;9(4):472. doi: 10.3390/jof9040472,wangqiannan@hainanu.edu.cn,FSE1 was not required for vegetative growth and conidiation of Foc TR4; Banana plantlets demonstrated that knock-out of FSE1 increased the disease index.,Y Yang 2023,2023,1 gene,"Yang-2023-A Novel Effector, FSE1, Regulates th",BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21775,PHI:124027,UniProt,X0L985,GenBank,EXM05395,,,54006,FSE1 (FOIG_03990),chromosome unknown,,,,,,5507,Fusarium oxysporum,1229665,f. sp. cubense TR4,Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),cv. Brazilian,,,Pseudostem,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37108926,PubMed,10.3390/jof9040472,J Fungi (Basel). 2023 Apr 14;9(4):472. doi: 10.3390/jof9040472,wangqiannan@hainanu.edu.cn,FSE1 was not required for vegetative growth and conidiation of Foc TR4; Banana plantlets demonstrated thatoverexpression of FSE1 decreased the disease index.,Y Yang 2023,2023,1 gene,"Yang-2023-A Novel Effector, FSE1, Regulates th",BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21776,PHI:124028,UniProt,A0A384JQU1,GenBank,ATZ52880,,,B05.10,Qdo (Bcin08g05000),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4054,Panax ginseng (related: Korean ginseng),,,,leaf,quercetin dioxygenase,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36312732,PubMed,10.1016/j.jgr.2022.03.005,J Ginseng Res. 2022 Nov;46(6):790-800. doi: 10.1016/j.jgr.2022.03.005. Epub 2022 Apr 4,emartz@uab.edu,The lesion sizes in ΔBcQdo infected ginseng leaves were smaller than B05.10.,H Chen 2022,2022,1 gene,Chen-2022-The necrotroph Botrytis cinerea prom,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21777,PHI:124028,UniProt,A0A384JQU1,GenBank,ATZ52880,,,B05.10,Qdo (Bcin08g05000),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3847,Glycine max (related: soybean),,,,leaf,quercetin dioxygenase,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36312732,PubMed,10.1016/j.jgr.2022.03.005,J Ginseng Res. 2022 Nov;46(6):790-800. doi: 10.1016/j.jgr.2022.03.005. Epub 2022 Apr 4,emartz@uab.edu,ΔBcQdo also delayed disease development in soybean at early stage.,H Chen 2022,2022,1 gene,Chen-2022-The necrotroph Botrytis cinerea prom,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21778,PHI:124029,,no data found,,,,,,RXLR1 (PHYCA_20942),,,,,,,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: silencing ; functional test in host: transient expression,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,"The pepper leaves treated with RXLR1-siRNAs exhibited smaller lesion and less P. capsici biomass, whereas the controls showed severe disease lesions and relative higher pathogen biomass; Transient overexpression of these RXLR effectors could not induce cell death response in pepper.",W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21779,PHI:124030,,no data found,,,,,,RXLR4 (PHYCA_107349),,,,,,,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: silencing ; functional test in host: transient expression,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,"The pepper leaves treated with RXLR4-siRNAs exhibited smaller lesion and less P. capsici biomass, whereas the controls showed severe disease lesions and relative higher pathogen biomass; Transient overexpression of these RXLR effectors could not induce cell death response in pepper.",W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21780,PHI:124029,,no data found,,,,,,RXLR1 (PHYCA_20942),,,,,,,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: silencing ; functional test in host: transient expression,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,"The N. benthamiana leaves treated with RXLR1-siRNAs exhibited smaller lesion and less P. capsici biomass, whereas the controls showed severe disease lesions and relative higher pathogen biomass; Transient overexpression of these RXLR effectors could not induce cell death response in tobacco.",W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21781,PHI:124030,,no data found,,,,,,RXLR4 (PHYCA_107349),,,,,,,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: silencing ; functional test in host: transient expression,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,"The N. benthamiana leaves treated with RXLR4-siRNAs exhibited smaller lesion and less P. capsici biomass, whereas the controls showed severe disease lesions and relative higher pathogen biomass; Transient overexpression of these RXLR effectors could not induce cell death response in tobacco.",W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21782,PHI:124029,,no data found,,,,,,RXLR1 (PHYCA_20942),,,,,,PHI:124030,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,"RXLR1-siRNAs and RXLR4-siRNAs are treated simultaneously at the same amount, N. benthamiana leaves displayed very mild disease symptoms, exhibiting much smaller lesions and less P. capsici growth.",W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21783,PHI:124030,,no data found,,,,,,RXLR4 (PHYCA_107349),,,,,,PHI:124029,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,"RXLR1-siRNAs and RXLR4-siRNAs are treated simultaneously at the same amount, N. benthamiana leaves displayed very mild disease symptoms, exhibiting much smaller lesions and less P. capsici growth.",W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21784,PHI:124029,,no data found,,,,,,RXLR1 (PHYCA_20942),,,,,,PHI:124030,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,"RXLR1-siRNAs and RXLR4-siRNAs are treated simultaneously at the same amount, pepper leaves displayed very mild disease symptoms, exhibiting much smaller lesions and less P. capsici growth.",W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21785,PHI:124030,,no data found,,,,,,RXLR4 (PHYCA_107349),,,,,,PHI:124029,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,"RXLR1-siRNAs and RXLR4-siRNAs are treated simultaneously at the same amount, pepper leaves displayed very mild disease symptoms, exhibiting much smaller lesions and less P. capsici growth.",W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21786,PHI:124031,,no data found,,,,,,RXLR2 (PHYCA_114125),,,,,,,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,Transient overexpression of these RXLR effectors could not induce cell death response in pepper and significantly could not promote P. capsici growth.,W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21787,PHI:124031,,no data found,,,,,,RXLR2 (PHYCA_114125),,,,,,,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,Transient overexpression of these RXLR effectors could not induce cell death response in N. benthamiana and significantly could not promote P. capsici growth.,W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21788,PHI:124032,,no data found,,,,,,RXLR3 (PHYCA_12939),,,,,,,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4072,Capsicum annuum (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,Transient overexpression of these RXLR effectors could not induce cell death response in pepper and significantly could not promote P. capsici growth.,W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21789,PHI:124032,,no data found,,,,,,RXLR3 (PHYCA_12939),,,,,,,4784,Phytophthora capsici,,JX1,crown infection; leaf spot; foliar blight,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression,,,NN,35196108,PubMed,10.1094/MPMI-12-21-0295-R,Mol Plant Microbe Interact. 2022 Jun;35(6):440-449. doi: 10.1094/MPMI-12-21-0295-R. Epub 2022 Apr 26,shlhe201304@aliyun.com,Transient overexpression of these RXLR effectors could not induce cell death response in N. benthamiana and significantly could not promote P. capsici growth.,W Cheng 2022,2022,4 genes,Cheng-2022-RNAi-Based Gene Silencing of RXLR E,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21790,PHI:124033,UniProt,A0A3T2H7M3,GenBank,QBZ18245,,,NCCP 15743,gsh-px,,,,,,,1639,Listeria monocytogenes,,Lm850658,listeriosis,rodents,10090,Mus musculus (related: house mouse),Kunming,,,liver; spleen; brain,glutathione peroxidase,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37032864,PubMed,10.3389/fmicb.2023.1122623,Front Microbiol. 2023 Mar 22;14:1122623. doi: 10.3389/fmicb.2023.1122623. eCollection 2023,fangchun@yangtzeu.edu.cn,"L. monocytogenes lacking GSH-Px could colonize and proliferate more efficiently in mice livers and spleens, enhancing the pathogenicity of L. monocytogenes by increasing the expression of virulence factors like InlA, InlB, and LLO.",Y Zhang 2023,2023,1 gene,Zhang-2023-Destroying glutathione peroxidase i,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21791,PHI:124034,,no data found,,,,,,ASvicK,,,,,,,1309,Streptococcus mutans,210007,UA159,infective endocarditis,rodents,10117,Rattus rattus (related: black rat),,,,tooth,antisense vicK RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37138664,PubMed,10.1080/20002297.2023.2204250,J Oral Microbiol. 2023 Apr 28;15(1):2204250. doi: 10.1080/20002297.2023.2204250. eCollection 2023,yangdeqin@hospital.cqmu.edu.cn,Overexpression of ASvicK can inhibit the growth of biofilm and affect the cariogenicity of S. mutans.,Y Sun 2023,2023,1 gene,Sun-2023-Exopolysaccharides metabolism and car,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21792,PHI:124035,,no data found,,,,,,Met14,,,,,,,5207,Cryptococcus neoformans,1298968,H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,adenylyl-sulfate kinase,,,methionine biosynthesis pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37036370,PubMed,10.1128/spectrum.00685-23,Microbiol Spectr. 2023 Apr 10:e0068523. doi: 10.1128/spectrum.00685-23. Online ahead of print,ysbahn@yonsei.ac.kr.,"In the insect-killing model using the larvae of Galleria mellonella, two independent met14D mutants showed significantly decreased virulence compared to the wild-type and its complemented strain.",S H Lee 2023,2023,1 gene,Lee-2023-Adenylyl-Sulfate Kinase (Met14)-Depen,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21793,PHI:124035,,no data found,,,,,,Met14,,,,,,,5207,Cryptococcus neoformans,1298968,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),,,,lung; brain; spleen; kidney; liver,adenylyl-sulfate kinase,,,methionine biosynthesis pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37036370,PubMed,10.1128/spectrum.00685-23,Microbiol Spectr. 2023 Apr 10:e0068523. doi: 10.1128/spectrum.00685-23. Online ahead of print,ysbahn@yonsei.ac.kr.,"In line with the survival curve, there was no change in virulence, the fungal burdens of met14D also showed no significant differences from those of the wild-type or the complemented strain.",S H Lee 2023,2023,1 gene,Lee-2023-Adenylyl-Sulfate Kinase (Met14)-Depen,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21794,PHI:124036,UniProt,B2WBG9,GenBank,EDU49901,,,Pt-1C-BFP,Pf2 (PTRG_06982),,,,,,,45151,Pyrenophora tritici-repentis,,race 5 isolate DW5,tan spot (wheat),monocots,4565,Triticum aestivum (related: bread wheat),cv. Katepwa; 6B662 line,,,leaf,transcription factor,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,37059688,PubMed,10.1111/mmi.15058,Mol Microbiol. 2023 May;119(5):612-629. doi: 10.1111/mmi.15058. Epub 2023 Apr 14,caroline.moffat@curtin.edu.au,Targeted deletion of PtrPf2 which resulted in reduced ToxB expression and defects in conidiation and pathogenicity.,P T See 2023,2023,1 gene,See-2023-Profiling the Pyrenophora tritici-rep,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21795,PHI:124037,UniProt,B0Y9W4,GenBank,EDP48807,,,A1163,ZfpA (AFUB_082490),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37126504,PubMed,10.1371/journal.ppat.1011152,PLoS Pathog. 2023 May 1;19(5):e1011152. doi: 10.1371/journal.ppat.1011152. eCollection 2023 May,huttenlocher@wisc.edu,Virulence of ΔzfpA was attenuated in wild-type control larvae (mpx:rac2wt).,T J Schoen 2023,2023,1 gene,Schoen-2023-Aspergillus fumigatus transcriptio,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21796,PHI:124037,UniProt,B0Y9W4,GenBank,EDP48807,,,A1163,ZfpA (AFUB_082490),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37126504,PubMed,10.1371/journal.ppat.1011152,PLoS Pathog. 2023 May 1;19(5):e1011152. doi: 10.1371/journal.ppat.1011152. eCollection 2023 May,huttenlocher@wisc.edu,Virulence of OE::zfpA was similar to WT CEA10 control larvae (mpx:rac2wt).,T J Schoen 2023,2023,1 gene,Schoen-2023-Aspergillus fumigatus transcriptio,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21797,PHI:124037,UniProt,B0Y9W4,GenBank,EDP48807,,,A1163,ZfpA (AFUB_082490),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37126504,PubMed,10.1371/journal.ppat.1011152,PLoS Pathog. 2023 May 1;19(5):e1011152. doi: 10.1371/journal.ppat.1011152. eCollection 2023 May,huttenlocher@wisc.edu,"In neutrophil-defective Rac2D57N larvae, ΔzfpA had similar virulence compared to WT CEA10.",T J Schoen 2023,2023,1 gene,Schoen-2023-Aspergillus fumigatus transcriptio,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21798,PHI:124037,UniProt,B0Y9W4,GenBank,EDP48807,,,A1163,ZfpA (AFUB_082490),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37126504,PubMed,10.1371/journal.ppat.1011152,PLoS Pathog. 2023 May 1;19(5):e1011152. doi: 10.1371/journal.ppat.1011152. eCollection 2023 May,huttenlocher@wisc.edu,"In neutrophil-defective Rac2D57N larvae, WT CEA10 97 remained less virulent than OE::zfpA.",T J Schoen 2023,2023,1 gene,Schoen-2023-Aspergillus fumigatus transcriptio,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21799,PHI:124037,UniProt,B0Y9W4,GenBank,EDP48807,,,A1163,ZfpA (AFUB_082490),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37126504,PubMed,10.1371/journal.ppat.1011152,PLoS Pathog. 2023 May 1;19(5):e1011152. doi: 10.1371/journal.ppat.1011152. eCollection 2023 May,huttenlocher@wisc.edu,Virulence of the ΔzfpA mutant was reduced relative to WT CEA10 in both p22+/+ and p22-/- larvae.,T J Schoen 2023,2023,1 gene,Schoen-2023-Aspergillus fumigatus transcriptio,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21800,PHI:124037,UniProt,B0Y9W4,GenBank,EDP48807,,,A1163,ZfpA (AFUB_082490),,,,,,,746128,Aspergillus fumigatus,505235,CEA10,invasive pulmonary aspergillosis,bony fishes,7955,Danio rerio (related: zebrafish),,,,larva,transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37126504,PubMed,10.1371/journal.ppat.1011152,PLoS Pathog. 2023 May 1;19(5):e1011152. doi: 10.1371/journal.ppat.1011152. eCollection 2023 May,huttenlocher@wisc.edu,Virulence of the OE::zfpA mutant was reduced relative to WT CEA10 in both p22+/+ and p22-/- larvae.,T J Schoen 2023,2023,1 gene,Schoen-2023-Aspergillus fumigatus transcriptio,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21801,PHI:124038,UniProt,A0A6L7HLW1,,,,,,brnQ3 (GBAA_1459),,,,,,,1392,Bacillus anthracis,,ANR-1,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung; liver; kidney; spleen,BCAA-related gene,,,BCAA biosynthesis pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35073743,PubMed,10.1128/mbio.03640-21,mBio. 2022 Feb 22;13(1):e0364021. doi: 10.1128/mbio.03640-21. Epub 2022 Jan 25,Theresa.M.Koehler@uth.tmc.edu,The brnQ3-null mutant was highly attenuated in this animal model. Nine of ten mice infected with this mutant survived infection and exhibited no signs of disease.,S Dutta 2022,2022,4 genes,Dutta-2022-BrnQ-Type Branched-Chain Amino Acid,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21802,PHI:124039,UniProt,Q81RI3,,,,,,brnQ4 (GBAA_2063),,,,,,,1392,Bacillus anthracis,,ANR-1,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung; liver; kidney; spleen,BCAA-related gene,,,BCAA biosynthesis pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35073743,PubMed,10.1128/mbio.03640-21,mBio. 2022 Feb 22;13(1):e0364021. doi: 10.1128/mbio.03640-21. Epub 2022 Jan 25,Theresa.M.Koehler@uth.tmc.edu,The time to death for mice infected with brnQ4- null mutant was not significantly different from the time to death for mice infected with the parent strain.,S Dutta 2022,2022,4 genes,Dutta-2022-BrnQ-Type Branched-Chain Amino Acid,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21803,PHI:124040,UniProt,A0A6L8NYJ7,,,,,,brnQ5 (GBAA_3142),,,,,,,1392,Bacillus anthracis,,ANR-1,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung; liver; kidney; spleen,BCAA-related gene,,,BCAA biosynthesis pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35073743,PubMed,10.1128/mbio.03640-21,mBio. 2022 Feb 22;13(1):e0364021. doi: 10.1128/mbio.03640-21. Epub 2022 Jan 25,Theresa.M.Koehler@uth.tmc.edu,The time to death for mice infected with brnQ5-null mutants was not significantly different from the time to death for mice infected with the parent strain.,S Dutta 2022,2022,4 genes,Dutta-2022-BrnQ-Type Branched-Chain Amino Acid,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21804,PHI:124041,UniProt,Q81S26,,,,,,ilvD,,,,,,,1392,Bacillus anthracis,,ANR-1,anthrax,rodents,10090,Mus musculus (related: house mouse),A/J,,,lung; liver; kidney; spleen,BCAA-related gene,,,BCAA biosynthesis pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35073743,PubMed,10.1128/mbio.03640-21,mBio. 2022 Feb 22;13(1):e0364021. doi: 10.1128/mbio.03640-21. Epub 2022 Jan 25,Theresa.M.Koehler@uth.tmc.edu,"Eighty percent of the mice injected with the ilvD-null mutant did not exhibit symptoms, survived infection, and had no recoverable CFU in their tissues.",S Dutta 2022,2022,4 genes,Dutta-2022-BrnQ-Type Branched-Chain Amino Acid,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21805,PHI:124042,UniProt,H8MA42,GenBank,AFD55984,,,ATCC 11845,SspA,,,,,,,34085,Riemerella anatipestifer,1455062,serotype 2 strain Yb2,fibrinous serositis; caseous salpingitis; vegetative disorder,birds,8839,Anas platyrhynchos (related: mallard),Cherry Valley,,,embryo,effector protein,,,,effector (plant avirulence determinant),,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,35575548,PubMed,10.1128/aem.02409-21,Appl Environ Microbiol. 2022 Jun 14;88(11):e0240921. doi: 10.1128/aem.02409-21. Epub 2022 May 16,yus@shvri.ac.cn,"The LD50 for mutant strain Yb2ΔsspA was 2.25 x109 CFU, which was >10,000-fold lower than that of the wild-type strain Yb2 (2.03 x105 CFU)",Z Chen 2022,2022,1 gene,Chen-2022-Riemerella anatipestifer T9SS Effect,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21806,PHI:124043,,no data found,,,,,,SaeRS,,,,,,,1311,Streptococcus agalactiae,,THN0901,neonatal pneumonia; neonatal meningitis; bovine mastitis; meningoencephalitis (fish),bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,brain; spleen; liver,unknown,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37138609,PubMed,10.3389/fmicb.2023.1121621,Front Microbiol. 2023 Apr 17;14:1121621. doi: 10.3389/fmicb.2023.1121621. eCollection 2023,lianxing@mail.sysu.edu.cn,"Mortality of tilapia caused by the ΔSaeRS strain was significantly decreased (23.3%), of which THN0901 and CΔSaeRS strains were 73.3%.",S Li 2023,2023,1 gene,Li-2023-Characterization and virulence of Stre,BATCH_122A,2023-05-01,MC,,,,,,,,,,,,,
,,Record 21807,PHI:124044,,no data found,,,,,,Casp8,,,,,,PHI:124045; PHI:124046; PHI:124047,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,caspase-8,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,"C. rodentium-infected Casp8–/–Ripk3–/–Casp1/11–/– mice showed severe body weight loss and died within 12 dpi, while the other cohorts survived the infection.",E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21808,PHI:124045,,no data found,,,,,,Ripk3,,,,,,PHI:124044; PHI:124046; PHI:124047,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,"C. rodentium-infected Casp8–/–Ripk3–/–Casp1/11–/– mice showed severe body weight loss and died within 12 dpi, while the other cohorts survived the infection.",E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21809,PHI:124046,,no data found,,,,,,Casp1,,,,,,PHI:124044; PHI:124045; PHI:124047,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,caspase-1,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,"C. rodentium-infected Casp8–/–Ripk3–/–Casp1/11–/– mice showed severe body weight loss and died within 12 dpi, while the other cohorts survived the infection.",E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21810,PHI:124047,,no data found,,,,,,Casp11,,,,,,PHI:124044; PHI:124045; PHI:124046,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,caspase-11,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,"C. rodentium-infected Casp8–/–Ripk3–/–Casp1/11–/– mice showed severe body weight loss and died within 12 dpi, while the other cohorts survived the infection.",E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21811,PHI:124044,,no data found,,,,,,Casp8,,,,,,PHI:124045; PHI:124048,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,caspase-8,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,Gsdmd on a Casp8–/–Ripk3–/– background did not reproduce the C. rodentium lethality phenotype.,E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21812,PHI:124045,,no data found,,,,,,Ripk3,,,,,,PHI:124044; PHI:124048,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,regulator,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,Gsdmd on a Casp8–/–Ripk3–/– background did not reproduce the C. rodentium lethality phenotype.,E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21813,PHI:124048,,no data found,,,,,,Gsdmd,,,,,,PHI:124044; PHI:124045,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,gasdermin D,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,Gsdmd on a Casp8–/–Ripk3–/– background did not reproduce the C. rodentium lethality phenotype.,E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21814,PHI:124044,,no data found,,,,,,Casp8,,,,,,PHI:124045; PHI:124046,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,caspase-8,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,C. rodentium-infected Casp8–/–Ripk3–/–Casp1–/– mice showed severe body weight loss.,E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21815,PHI:124045,,no data found,,,,,,Ripk3,,,,,,PHI:124044; PHI:124046,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,C. rodentium-infected Casp8–/–Ripk3–/–Casp1–/– mice showed severe body weight loss,E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21816,PHI:124046,,no data found,,,,,,Casp1,,,,,,PHI:124044; PHI:124045,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,caspase-1,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,C. rodentium-infected Casp8–/–Ripk3–/–Casp1–/– mice showed severe body weight loss.,E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21817,PHI:124044,,no data found,,,,,,Casp8,,,,,,PHI:124045; PHI:124047,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,caspase-8,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,C. rodentium-infected Casp8–/–Ripk3–/–Casp11–/– mice showed severe body weight loss.,E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21818,PHI:124045,,no data found,,,,,,Ripk3,,,,,,PHI:124044; PHI:124047,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,C. rodentium-infected Casp8–/–Ripk3–/–Casp11–/– mice showed severe body weight loss.,E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21819,PHI:124047,,no data found,,,,,,Casp11,,,,,,PHI:124044; PHI:124045,67825,Citrobacter rodentium,,,colitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,bone marrow-derived macrophage; femur; tibia; spleen,caspase-11,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37080966,PubMed,10.1038/s41419-023-05801-4,Cell Death Dis. 2023 Apr 21;14(4):282. doi: 10.1038/s41419-023-05801-4,andy.wullaert@uantwerpen.be,C. rodentium-infected Casp8–/–Ripk3–/–Casp11–/– mice showed severe body weight loss.,E Eeckhout 2023,2023,5 genes,Eeckhout-2023-Gasdermin D independent canonica,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21820,PHI:124049,UniProt,J5K3A2,GenBank,EJP70798,,,ARSEF 2860,RNT2 (BBA_00428),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,secretory T2 RNases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37122240,PubMed,10.1021/acs.jafc.3c01617,J Agric Food Chem. 2023 May 10;71(18):7069-7081. doi: 10.1021/acs.jafc.3c01617. Epub 2023 Apr 25,yjzhang@swu.edu.cn,There was no obvious difference in fungal virulence between ΔBbRNT2 and the wild type strains.,Y Yue 2023,2023,2 genes,Yue-2023-Two Secretory T2 RNases Act as Cytoto,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21821,PHI:124050,UniProt,J4UV04,GenBank,EJP69897,,,ARSEF 2860,Trv (BBA_00766),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,secretory T2 RNases,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37122240,PubMed,10.1021/acs.jafc.3c01617,J Agric Food Chem. 2023 May 10;71(18):7069-7081. doi: 10.1021/acs.jafc.3c01617. Epub 2023 Apr 25,yjzhang@swu.edu.cn,There was no obvious difference in fungal virulence between ΔBbTrv and the wild type strains.,Y Yue 2023,2023,2 genes,Yue-2023-Two Secretory T2 RNases Act as Cytoto,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21822,PHI:124049,UniProt,J5K3A2,GenBank,EJP70798,,,ARSEF 2860,RNT2 (BBA_00428),chromosome unknown,,,,,PHI:124050,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,secretory T2 RNases,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37122240,PubMed,10.1021/acs.jafc.3c01617,J Agric Food Chem. 2023 May 10;71(18):7069-7081. doi: 10.1021/acs.jafc.3c01617. Epub 2023 Apr 25,yjzhang@swu.edu.cn,"A significant decrease in mortality of infected insects was examined with the double gene disruption mutant strain (ΔBbRNT2 + ΔBbTrv, DKO) as compared to the wild type strain.",Y Yue 2023,2023,2 genes,Yue-2023-Two Secretory T2 RNases Act as Cytoto,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21823,PHI:124050,UniProt,J4UV04,GenBank,EJP69897,,,ARSEF 2860,Trv (BBA_00766),chromosome unknown,,,,,PHI:124049,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,secretory T2 RNases,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37122240,PubMed,10.1021/acs.jafc.3c01617,J Agric Food Chem. 2023 May 10;71(18):7069-7081. doi: 10.1021/acs.jafc.3c01617. Epub 2023 Apr 25,yjzhang@swu.edu.cn,"A significant decrease in mortality of infected insects was examined with the double gene disruption mutant strain (ΔBbRNT2 + ΔBbTrv, DKO) as compared to the wild type strain.",Y Yue 2023,2023,2 genes,Yue-2023-Two Secretory T2 RNases Act as Cytoto,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21824,PHI:124049,UniProt,J5K3A2,GenBank,EJP70798,,,ARSEF 2860,RNT2 (BBA_00428),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,secretory T2 RNases,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37122240,PubMed,10.1021/acs.jafc.3c01617,J Agric Food Chem. 2023 May 10;71(18):7069-7081. doi: 10.1021/acs.jafc.3c01617. Epub 2023 Apr 25,yjzhang@swu.edu.cn,"More rapid death of infected insects was seen for the overexpression strains, but no significant difference was seen in the mortality caused by BbRNT2OE, BbTrvOE, or DOE (overexpressing the double genes, BbRNT2OE + BbTrvOE) strains.",Y Yue 2023,2023,2 genes,Yue-2023-Two Secretory T2 RNases Act as Cytoto,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21825,PHI:124050,UniProt,J4UV04,GenBank,EJP69897,,,ARSEF 2860,Trv (BBA_00766),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,secretory T2 RNases,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37122240,PubMed,10.1021/acs.jafc.3c01617,J Agric Food Chem. 2023 May 10;71(18):7069-7081. doi: 10.1021/acs.jafc.3c01617. Epub 2023 Apr 25,yjzhang@swu.edu.cn,"More rapid death of infected insects was seen for the overexpression strains, but no significant difference was seen in the mortality caused by BbRNT2OE, BbTrvOE, or DOE (overexpressing the double genes, BbRNT2OE + BbTrvOE) strains.",Y Yue 2023,2023,2 genes,Yue-2023-Two Secretory T2 RNases Act as Cytoto,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21826,PHI:124049,UniProt,J5K3A2,GenBank,EJP70798,,,ARSEF 2860,RNT2 (BBA_00428),chromosome unknown,,,,,PHI:124050,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,secretory T2 RNases,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37122240,PubMed,10.1021/acs.jafc.3c01617,J Agric Food Chem. 2023 May 10;71(18):7069-7081. doi: 10.1021/acs.jafc.3c01617. Epub 2023 Apr 25,yjzhang@swu.edu.cn,"More rapid death of infected insects was seen for the overexpression strains, but no significant difference was seen in the mortality caused by BbRNT2OE, BbTrvOE, or DOE (overexpressing the double genes, BbRNT2OE + BbTrvOE) strains.",Y Yue 2023,2023,2 genes,Yue-2023-Two Secretory T2 RNases Act as Cytoto,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21827,PHI:124050,UniProt,J4UV04,GenBank,EJP69897,,,ARSEF 2860,Trv (BBA_00766),chromosome unknown,,,,,PHI:124049,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,secretory T2 RNases,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37122240,PubMed,10.1021/acs.jafc.3c01617,J Agric Food Chem. 2023 May 10;71(18):7069-7081. doi: 10.1021/acs.jafc.3c01617. Epub 2023 Apr 25,yjzhang@swu.edu.cn,"More rapid death of infected insects was seen for the overexpression strains, but no significant difference was seen in the mortality caused by BbRNT2OE, BbTrvOE, or DOE (overexpressing the double genes, BbRNT2OE + BbTrvOE) strains.",Y Yue 2023,2023,2 genes,Yue-2023-Two Secretory T2 RNases Act as Cytoto,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21828,PHI:124051,UniProt,A0A5S4TQ21,GenBank,TYK95700,,,SPY5003,dacA,,,,,,,1314,Streptococcus pyogenes,1336746,HSC5,infection,rodents,10090,Mus musculus (related: house mouse),SKH1,,,,c-di-AMP synthase gene,,,,loss of pathogenicity,,,,,no lesion,,,defective,,no,,,,,,,gene deletion: full,,,NN,33468578,PubMed,10.1128/IAI.00317-20,Infect Immun. 2021 Mar 17;89(4):e00317-20. doi: 10.1128/IAI.00317-20. Print 2021 Mar 17,kyuhong.cho@indstate.edu,"The ΔdacA mutant displays no virulence in a murine subcutaneous infection model, as seen by the absence of a lesion.",S Faozia 2021,2021,2 genes,Faozia-2021-c-di-AMP-Regulated K(+) Importer K,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21829,PHI:124051,UniProt,A0A5S4TQ21,GenBank,TYK95700,,,SPY5003,dacA,,,,,,PHI:124052,1314,Streptococcus pyogenes,1336746,HSC5,infection,rodents,10090,Mus musculus (related: house mouse),SKH1,,,,c-di-AMP synthase gene,,,,loss of pathogenicity,,,,,no lesion,,,wild type,,no,,,,,,,gene deletion: full,,,NN,33468578,PubMed,10.1128/IAI.00317-20,Infect Immun. 2021 Mar 17;89(4):e00317-20. doi: 10.1128/IAI.00317-20. Print 2021 Mar 17,kyuhong.cho@indstate.edu,"The virulence of the ΔdacA ΔktrB mutant was examined using the same soft-tissue infection model, and, none of the mice injected with the ΔdacA ΔktrB mutant developed lesions.",S Faozia 2021,2021,2 genes,Faozia-2021-c-di-AMP-Regulated K(+) Importer K,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21830,PHI:124052,UniProt,Q9A1D8,GenBank,AAK33384,,,SF370,ktrB,,,,,,PHI:124051,1314,Streptococcus pyogenes,1336746,HSC5,infection,rodents,10090,Mus musculus (related: house mouse),SKH1,,,,subunit of the K1 transport system ktrAB,,,,loss of pathogenicity,,,,,no lesion,,,wild type,,no,,,,,,,gene deletion: full,,,NN,33468578,PubMed,10.1128/IAI.00317-20,Infect Immun. 2021 Mar 17;89(4):e00317-20. doi: 10.1128/IAI.00317-20. Print 2021 Mar 17,kyuhong.cho@indstate.edu,"The virulence of the ΔdacA ΔktrB mutant was examined using the same soft-tissue infection model, and, none of the mice injected with the ΔdacA ΔktrB mutant developed lesions.",S Faozia 2021,2021,2 genes,Faozia-2021-c-di-AMP-Regulated K(+) Importer K,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21831,PHI:124053,UniProt,B0XNW9,GenBank,EDP56873,,,A1163,spt20 (AFUB_015950),,,,ptaB; SomA,UniProt: Q4X0N1; GenBank: EAL93584; UniProt: Q4WAR8; GenBank: EAL84668,,746128,Aspergillus fumigatus,,A1160,invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,subunit of the SAGA complex,,,,reduced virulence,,,,,fewer lesions,defective,,defective,,no,,,,,,,gene deletion: full,,,NN,34669434,PubMed,10.1128/AEM.01535-21,Appl Environ Microbiol. 2022 Jan 11;88(1):e0153521. doi: 10.1128/AEM.01535-21. Epub 2021 Oct 20,linglu@njnu.edu.cn,Mice infected with the Tet-spt20 strain without doxycycline supplementation exhibited improved survival compared with mice treated with doxycycline as well as mice infected with WT A. fumigatus both with and without doxycycline treatment.,Y Chen 2022,2022,1 gene,"Chen-2022-Spt20, a Structural Subunit of the S",BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21832,PHI:124054,UniProt,D0N8M8,GenBank,EEY53913,,,T30-4,Avr8 (PITG_07558),,,,,,,4787,Phytophthora infestans,,HB1501,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Désirée R8,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37083862,PubMed,10.1371/journal.ppat.1011346,PLoS Pathog. 2023 Apr 21;19(4):e1011346. doi: 10.1371/journal.ppat.1011346. eCollection 2023 Apr,huangsanwen@caas.cn,"Compared with unedited T22 and wild type HB1501, T3 and T10 caused lesions of significantly larger size upon infection of R8 transgenic potato leaves.",L Wang 2023,2023,2 genes,Wang-2023-A modified Agrobacterium-mediated tr,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21833,PHI:124054,UniProt,D0N8M8,GenBank,EEY53913,,,T30-4,Avr8 (PITG_07558),,,,,,,4787,Phytophthora infestans,,HB1501,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Désirée,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37083862,PubMed,10.1371/journal.ppat.1011346,PLoS Pathog. 2023 Apr 21;19(4):e1011346. doi: 10.1371/journal.ppat.1011346. eCollection 2023 Apr,huangsanwen@caas.cn,T3 and T10 caused infection symptoms similar to T22 and wild type HB1501 when using detached leaves from susceptible wild type potato (De´sire´e WT) lacking the R8 gene.,L Wang 2023,2023,2 genes,Wang-2023-A modified Agrobacterium-mediated tr,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21834,PHI:124055,UniProt,D0N758,GenBank,EEY53407,,,T30-4,MADS-box (PITG_07059),,,,,,,4787,Phytophthora infestans,,JH19,late blight (potato),eudicots,4113,Solanum tuberosum (related: potato),cv. Désirée,,,leaf,transcription factor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37083862,PubMed,10.1371/journal.ppat.1011346,PLoS Pathog. 2023 Apr 21;19(4):e1011346. doi: 10.1371/journal.ppat.1011346. eCollection 2023 Apr,huangsanwen@caas.cn,T5 and wild type JH19 strains caused complete infectious lesions and developed obvious aerial mycelia. whereas T8 and T16 only showed partial watery lesions without formation of aerial mycelia.,L Wang 2023,2023,2 genes,Wang-2023-A modified Agrobacterium-mediated tr,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21835,PHI:124056,UniProt,Q8XBV2,GenBank,AF175707_1,,,O157 KNIH317,stx2a,,,,,,,562,Escherichia coli,,JH2010,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,Shiga toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37022201,PubMed,10.1128/spectrum.00372-23,Microbiol Spectr. 2023 Apr 6:e0037223. doi: 10.1128/spectrum.00372-23. Online ahead of print,angela.melton-celsa@usuhs.edu,"Str-treated mice were orally infected with JH2010 or JH2010ΔSR2af, we unexpectedly found that the deletion of the stx2a phage lytic genes in JH2010 had no impact on the survival or fecal cytotoxicity of the infected mice.",R R Atitkar 2023,2023,1 gene,Atitkar-2023-Shiga Toxin (Stx) Phage-Encoded L,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21836,PHI:124057,UniProt,Q8XBV2,GenBank,AF175707_1,,,O157 KNIH317,stx2a,,,,,,,562,Escherichia coli,,JH2016,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,Shiga toxin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37022201,PubMed,10.1128/spectrum.00372-23,Microbiol Spectr. 2023 Apr 6:e0037223. doi: 10.1128/spectrum.00372-23. Online ahead of print,angela.melton-celsa@usuhs.edu,"Mice infected with either JH2016 or JH2016ΔSR2af exhibited a similar, intermediate phenotype of virulence, in contrast to the complete lethality of JH2016 at 1010–11 CFU.",R R Atitkar 2023,2023,1 gene,Atitkar-2023-Shiga Toxin (Stx) Phage-Encoded L,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21837,PHI:124058,UniProt,Q9F0H5,GenBank,AAG33881,,,DC3000,hrpP,,,,,,,317,Pseudomonas syringae,223283,DC3000,bacterial speck,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,,type III secretion protein,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37067445,PubMed,10.1128/spectrum.05148-22,Microbiol Spectr. 2023 Apr 17:e0514822. doi: 10.1128/spectrum.05148-22. Online ahead of print,,HrpP in Arabidopsis partially restored the virulence of the hrpP mutant.,Y Jin 2023,2023,1 gene,Jin-2023-Pseudomonas syringae Type III Secreti,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21838,PHI:124059,UniProt,J9VH79,GenBank,AFR92731,,,H99,cel1,chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,"endo-beta-1,4-glucanase D",,,signal transduction pathway.,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37099613,PubMed,10.1371/journal.ppat.1010946,PLoS Pathog. 2023 Apr 26;19(4):e1010946. doi: 10.1371/journal.ppat.1010946. eCollection 2023 Apr,andrew.alspaugh@duke.edu,"The wild-type and complemented strains demonstrated a similar level of virulence in this model, with 50% of the infected animals dying from the infection after 21–24 days whereas all mice infected with the cel1Δ mutant strain survived 8-weeks after inoculation, with none exhibiting symptoms associated with infection.",C Probst 2023,2023,1 gene,Probst-2023-A fungal lytic polysaccharide mono,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21839,PHI:124059,UniProt,J9VH79,GenBank,AFR92731,,,H99,cel1,chromosome 1,,,,,,5207,Cryptococcus neoformans,235443,var. grubii strain H99,fungal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"endo-beta-1,4-glucanase D",,,signal transduction pathway.,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37099613,PubMed,10.1371/journal.ppat.1010946,PLoS Pathog. 2023 Apr 26;19(4):e1010946. doi: 10.1371/journal.ppat.1010946. eCollection 2023 Apr,andrew.alspaugh@duke.edu,Larvae infected with either the WT or complemented strains displayed similar rates of host death at both temperatures whereas there was a significant increase in host survival at both temperatures after infection with the cel1Δ mutant.,C Probst 2023,2023,1 gene,Probst-2023-A fungal lytic polysaccharide mono,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21840,PHI:124060,UniProt,J4UTH7,GenBank,EJP69137,,,ARSEF 2860,Ada2 (EJP69137.1),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,transcriptional adapter 2,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37052485,PubMed,10.1128/spectrum.00281-23,Microbiol Spectr. 2023 Apr 13:e0028123. doi: 10.1128/spectrum.00281-23. Online ahead of print,qiulei.2005@163.com,"The larvae treated with WT died completely by day 7, while the mutant strain did not kill the larvae. After 10 days of infection, larvae in the ΔAda2 treatment group showed a survival rate of 95.66%.",S J Hu 2023,2023,2 genes,Hu-2023-Ada2 and Ada3 Regulate Hyphal Growth,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21841,PHI:124060,UniProt,J5K3I2,GenBank,EJP70893,,,ARSEF 2860,Ada3 (EJP70893.1),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,histone acetyltransferase subunit 3,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37052485,PubMed,10.1128/spectrum.00281-23,Microbiol Spectr. 2023 Apr 13:e0028123. doi: 10.1128/spectrum.00281-23. Online ahead of print,qiulei.2005@163.com,"The larvae treated with WT died completely by day 7, while the mutant strain did not kill the larvae. After 10 days of infection, larvae in the ΔAda3treatment group showed a survival rate of 85.56%.",S J Hu 2023,2023,2 genes,Hu-2023-Ada2 and Ada3 Regulate Hyphal Growth,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21842,PHI:124061,UniProt,Q9HY46,GenBank,AAG06962,,,,nalD,,nalDT158P; rneΔ50bp; rne::Tn,,,,PHI:12280,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage; femur; tibia,multidrug-resistant protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,37027441,PubMed,10.1371/journal.ppat.1010942,PLoS Pathog. 2023 Apr 7;19(4):e1010942. doi: 10.1371/journal.ppat.1010942. eCollection 2023 Apr,peter.jorth@cshs.org,"Bacterial burden during BMDM infection and BMDM cytotoxicity were increased in nalDT158P, rneΔ50bp and rne::Tn mutants compared to WT.",M Vaillancourt 2023,2023,1 gene,Vaillancourt-2023-A compensatory RNase E varia,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21843,PHI:12280,UniProt,Q9HZM8,GenBank,AAG06364,,,,rne,,nalDT158P; rneΔ50bp; rne::Tn,,,,PHI:124061,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,bone marrow-derived macrophage; femur; tibia,multidrug-resistant protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,37027441,PubMed,10.1371/journal.ppat.1010942,PLoS Pathog. 2023 Apr 7;19(4):e1010942. doi: 10.1371/journal.ppat.1010942. eCollection 2023 Apr,peter.jorth@cshs.org,"Bacterial burden during BMDM infection and BMDM cytotoxicity were increased in nalDT158P, rneΔ50bp and rne::Tn mutants compared to WT.",M Vaillancourt 2023,2023,1 gene,Vaillancourt-2023-A compensatory RNase E varia,BATCH_122B,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21844,PHI:124062,UniProt,A0A2J9QFB3,GenBank,PNM01266,,,FDAARGOS_258,prsA,,,,,,,1309,Streptococcus mutans,,GS5,infective endocarditis,rodents,10114,Rattus (related: rat),,,,heart,,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35876630,PubMed,10.1080/21505594.2022.2105351,Virulence. 2022 Dec;13(1):1379-1392. doi: 10.1080/21505594.2022.2105351,cjjung@tmu.edu.tw,"prsA deficient strain had reduced virulence in terms of formation of vegetation on damaged heart valves, as well as reduced autolysis activity, eDNA release and biofilm formation capacity.",C C Hsu 2022,2022,1 gene,Hsu-2022-Streptococcus mutans PrsA mediates At,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21845,PHI:124063,UniProt,A0A289ZXQ7,GenBank,ATA66928,,,EXAP-08,WC1,,,,,,,282267,Fusarium asiaticum,,EXAP-08,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68,,,coleoptile,white collar 1,,,HOG MAPK signaling pathwa,reduced virulence,,,,,smaller lesions,wild type,,wild type,wild type,no,,,,,,,gene deletion: full; gene complementation,,,NN,37195224,PubMed,10.1128/spectrum.05206-22,Microbiol Spectr. 2023 Jun 15;11(3):e0520622. doi: 10.1128/spectrum.05206-22. Epub 2023 May 17,lxu@bio.ecnu.edu.cn,Infection with the WT caused larger decaying areas than infection with the ΔFawc1 mutant.,Y Tang 2023,2023,2 genes,Tang-2023-White Collar 1 Modulates Oxidative S,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21846,PHI:124064,,no data found,,,,,,hog1,,,,,,,282267,Fusarium asiaticum,,EXAP-08,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68,,,coleoptile,high-osmolarity glycerol gene,,,HOG MAPK signaling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced ; defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37195224,PubMed,10.1128/spectrum.05206-22,Microbiol Spectr. 2023 Jun 15;11(3):e0520622. doi: 10.1128/spectrum.05206-22. Epub 2023 May 17,lxu@bio.ecnu.edu.cn,ΔFahog1 mutant caused significantly smaller lesion areas than the WT strain.,Y Tang 2023,2023,2 genes,Tang-2023-White Collar 1 Modulates Oxidative S,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21847,PHI:124064,,no data found,,,,,,hog1,,ΔFawc1::FaHOG1OE; ΔFahog1::FaHOG1OE,,,,,282267,Fusarium asiaticum,,EXAP-08,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Zhongyuan 98-68,,,coleoptile,high-osmolarity glycerol gene,,,HOG MAPK signaling pathway,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene complementation; altered gene expression / gene regulation: overexpression,,,NN,37195224,PubMed,10.1128/spectrum.05206-22,Microbiol Spectr. 2023 Jun 15;11(3):e0520622. doi: 10.1128/spectrum.05206-22. Epub 2023 May 17,lxu@bio.ecnu.edu.cn,ΔFawc1::FaHOG1OE and ΔFahog1::FaHOG1OE strains caused lesions with severities comparable to that of lesions caused by the WT.,Y Tang 2023,2023,2 genes,Tang-2023-White Collar 1 Modulates Oxidative S,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21848,PHI:124063,UniProt,A0A289ZXQ7,GenBank,ATA66928,,,EXAP-08,WC1,,,,,,,282267,Fusarium asiaticum,,EXAP-08,Fusarium head blight,monocots,4577,Zea mays (related: maize),B73 line,,,stem,white collar 1,,,HOG MAPK signaling pathwa,reduced virulence,,,,,smaller lesions,reduced,,reduced ; defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37195224,PubMed,10.1128/spectrum.05206-22,Microbiol Spectr. 2023 Jun 15;11(3):e0520622. doi: 10.1128/spectrum.05206-22. Epub 2023 May 17,lxu@bio.ecnu.edu.cn,ΔFahog1 mutant showed apparent defects in causing stem rot symptoms when they were inoculated on maize stems.,Y Tang 2023,2023,2 genes,Tang-2023-White Collar 1 Modulates Oxidative S,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21849,PHI:124064,,no data found,,,,,,hog1,,,,,,,282267,Fusarium asiaticum,,EXAP-08,Fusarium head blight,monocots,4577,Zea mays (related: maize),B73 line,,,stem,high-osmolarity glycerol gene,,,HOG MAPK signaling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced ; defective,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37195224,PubMed,10.1128/spectrum.05206-22,Microbiol Spectr. 2023 Jun 15;11(3):e0520622. doi: 10.1128/spectrum.05206-22. Epub 2023 May 17,lxu@bio.ecnu.edu.cn,ΔFahog1 mutants both caused significantly smaller lesion areas than the WT strain.,Y Tang 2023,2023,2 genes,Tang-2023-White Collar 1 Modulates Oxidative S,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21850,PHI:124064,,no data found,,,,,,hog1,,ΔFawc1::FaHOG1OE; ΔFahog1::FaHOG1OE,,,,,282267,Fusarium asiaticum,,EXAP-08,Fusarium head blight,monocots,4577,Zea mays (related: maize),B73 line,,,stem,high-osmolarity glycerol gene,,,HOG MAPK signaling pathway,increased virulence (hypervirulence),,,,,larger lesions,wild type,,wild type,,no,,,,,,,gene complementation; altered gene expression / gene regulation: overexpression,,,NN,37195224,PubMed,10.1128/spectrum.05206-22,Microbiol Spectr. 2023 Jun 15;11(3):e0520622. doi: 10.1128/spectrum.05206-22. Epub 2023 May 17,lxu@bio.ecnu.edu.cn,ΔFawc1::FaHOG1OE and ΔFahog1::FaHOG1OE strains caused levels of stem rot similar to or higher than the WT strain.,Y Tang 2023,2023,2 genes,Tang-2023-White Collar 1 Modulates Oxidative S,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21851,PHI:124065,,no data found,,,,,,SCP23,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,seedling; root,small cysteine-rich protein,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene complementation; altered gene expression / gene regulation: overexpression,,,NN,37298354,PubMed,10.3390/ijms24119403,Int J Mol Sci. 2023 May 28;24(11):9403. doi: 10.3390/ijms24119403,xiaojuanhao@sxau.edu.cn,Virulence of ΔVdSCP23 was not affected after VdSCP23 deletion in N. benthamiana seedlings compared to the wild-type strain.,J Wang 2023,2023,1 gene,Wang-2023-The Verticillium dahliae Small Cyste,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21852,PHI:124065,,no data found,,,,,,SCP23,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Junmian 1,,,seedling; root,small cysteine-rich protein,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene complementation; altered gene expression / gene regulation: overexpression,,,NN,37298354,PubMed,10.3390/ijms24119403,Int J Mol Sci. 2023 May 28;24(11):9403. doi: 10.3390/ijms24119403,xiaojuanhao@sxau.edu.cn,Virulence of ΔVdSCP23 was not affected after VdSCP23 deletion in Cotton seedlings compared to the wild-type strain.,J Wang 2023,2023,1 gene,Wang-2023-The Verticillium dahliae Small Cyste,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21853,PHI:124065,,no data found,,,,,,SCP23,,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,small cysteine-rich protein,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene complementation; altered gene expression / gene regulation: overexpression,,,NN,37298354,PubMed,10.3390/ijms24119403,Int J Mol Sci. 2023 May 28;24(11):9403. doi: 10.3390/ijms24119403,xiaojuanhao@sxau.edu.cn,Virulence of ΔVdSCP23 was not affected after VdSCP23 deletion in Arabidopsis thaliana seedlings compared to the wild-type strain.,J Wang 2023,2023,1 gene,Wang-2023-The Verticillium dahliae Small Cyste,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21854,PHI:124066,UniProt,Q17ZY6,GenBank,CAJ70139,,,630,prdB,,,,,,,1496,Clostridioides difficile,,ATCC 43255,nosocomial diarrhea,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,proline reductase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37292778,PubMed,10.1101/2023.05.19.541423,bioRxiv. 2023 May 20:2023.05.19.541423. doi: 10.1101/2023.05.19.541423. Preprint,lcersosimo@bwh.harvard.edu,"Mice infected with the ΔprdB mutant demonstrated extended survival via delayed colonization, growth and toxin production but ultimately succumbed to disease.",L M Cersosimo 2023,2023,1 gene,Cersosimo-2023-Central in vivo mechanisms by w,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21855,PHI:124067,UniProt,D4GHY6,,,,,,iucA (PAGR_g3927),,,,,,PHI:124068; PHI:124069,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"Aerobactin gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21856,PHI:124068,UniProt,D4GHY7,,,,,,iucB (PAGR_g3926),,,,,,PHI:124067; PHI:124069,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"Aerobactin gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21857,PHI:124069,UniProt,D4GHY9,,,,,,iucC (PAGR_g3925),,,,,,PHI:124067; PHI:124068,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"Aerobactin gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21858,PHI:124067,UniProt,D4GHY6,,,,,,iucA (PAGR_g3927),,,,,,PHI:124068; PHI:124069,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"Aerobactin gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21859,PHI:124068,UniProt,D4GHY7,,,,,,iucB (PAGR_g3926),,,,,,PHI:124067; PHI:124069,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"Aerobactin gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21860,PHI:124069,UniProt,D4GHY9,,,,,,iucC (PAGR_g3925),,,,,,PHI:124067; PHI:124068,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"Aerobactin gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21861,PHI:124070,,no data found,,,,,,dfoA (PAGR_g3562),,,,,,,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"desferrioxamine E (DFO-E) siderophores gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21862,PHI:124070,,no data found,,,,,,dfoA (PAGR_g3562),,,,,,,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"desferrioxamine E (DFO-E) siderophores gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21863,PHI:124071,,no data found,,,,,,dfoC (PAGR_g3561),,,,,,,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"desferrioxamine E (DFO-E) siderophores gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21864,PHI:124071,,no data found,,,,,,dfoC (PAGR_g3561),,,,,,,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"desferrioxamine E (DFO-E) siderophores gene mutant exhibited severe rot symptoms on onoin bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21865,PHI:124070,,no data found,,,,,,dfoA (PAGR_g3562),,,,,,PHI:124071,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"desferrioxamine E (DFO-E) siderophores double gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21866,PHI:124071,,no data found,,,,,,dfoC (PAGR_g3561),,,,,,PHI:124070,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"desferrioxamine E (DFO-E) siderophores double gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21867,PHI:124070,,no data found,,,,,,dfoA (PAGR_g3562),,,,,,PHI:124071,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"desferrioxamine E (DFO-E) siderophores double gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21868,PHI:124071,,no data found,,,,,,dfoC (PAGR_g3561),,,,,,PHI:124070,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"desferrioxamine E (DFO-E) siderophores double gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21869,PHI:124067,UniProt,D4GHY6,,,,,,iucA (PAGR_g3927),,,,,,PHI:124068; PHI:124069; PHI:124070,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21870,PHI:124068,UniProt,D4GHY7,,,,,,iucB (PAGR_g3926),,,,,,PHI:124067; PHI:124069; PHI:124070,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21871,PHI:124069,UniProt,D4GHY9,,,,,,iucC (PAGR_g3925),,,,,,PHI:124067; PHI:124068; PHI:124070,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21872,PHI:124070,,no data found,,,,,,dfoA (PAGR_g3562),,,,,,PHI:124067; PHI:124068; PHI:124069,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21873,PHI:124067,UniProt,D4GHY6,,,,,,iucA (PAGR_g3927),,,,,,PHI:124068; PHI:124069; PHI:124070,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21874,PHI:124068,UniProt,D4GHY7,,,,,,iucB (PAGR_g3926),,,,,,PHI:124067; PHI:124069; PHI:124070,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21875,PHI:124069,UniProt,D4GHY9,,,,,,iucC (PAGR_g3925),,,,,,PHI:124067; PHI:124068; PHI:124070,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21876,PHI:124070,,no data found,,,,,,dfoA (PAGR_g3562),,,,,,PHI:124067; PHI:124068; PHI:124069,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21877,PHI:124070,,no data found,,,,,,dfoC (PAGR_g3561),,,,,,PHI:124067; PHI:124068; PHI:124069,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21878,PHI:124070,,no data found,,,,,,dfoC (PAGR_g3561),,,,,,PHI:124067; PHI:124068; PHI:124069,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21879,PHI:124067,UniProt,D4GHY6,,,,,,iucA (PAGR_g3927),,,,,,PHI:124068; PHI:124069; PHI:124070; PHI:124071,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21880,PHI:124068,UniProt,D4GHY7,,,,,,iucB (PAGR_g3926),,,,,,PHI:124067; PHI:124069; PHI:124070; PHI:124071,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21881,PHI:124069,UniProt,D4GHY9,,,,,,iucC (PAGR_g3925),,,,,,PHI:124067; PHI:124068; PHI:124070; PHI:124071,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21882,PHI:124070,,no data found,,,,,,dfoA (PAGR_g3562),,,,,,PHI:124067; PHI:124068; PHI:124069; PHI:124071,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21883,PHI:124071,,no data found,,,,,,dfoC (PAGR_g3561),,,,,,PHI:124067; PHI:124068; PHI:124069; PHI:124070,553,Pantoea ananatis,1095774,PA13,,monocots,4530,Oryza sativa (related: rice),cv. Dongjin,,,seedling,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on rice sheaths, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21884,PHI:124067,UniProt,D4GHY6,,,,,,iucA (PAGR_g3927),,,,,,PHI:124068; PHI:124069; PHI:124070; PHI:124071,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21885,PHI:124068,UniProt,D4GHY7,,,,,,iucB (PAGR_g3926),,,,,,PHI:124067; PHI:124069; PHI:124070; PHI:124071,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21886,PHI:124069,UniProt,D4GHY9,,,,,,iucC (PAGR_g3925),,,,,,PHI:124067; PHI:124068; PHI:124070; PHI:124071,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,aerobactin siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21887,PHI:124070,,no data found,,,,,,dfoA (PAGR_g3562),,,,,,PHI:124067; PHI:124068; PHI:124069; PHI:124071,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21888,PHI:124071,,no data found,,,,,,dfoC (PAGR_g3561),,,,,,PHI:124067; PHI:124068; PHI:124069; PHI:124070,553,Pantoea ananatis,1095774,PA13,,monocots,4679,Allium cepa (related: onion),,,,bulb,desferrioxamine E (DFO-E) siderophores,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35108090,PubMed,10.1128/aem.02405-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0240521. doi: 10.1128/aem.02405-21. Epub 2022 Feb 2,jinwoo@gnu.ac.kr,"All aerobactin and DFO-E gene mutant exhibited severe rot symptoms on onion bulbs, with no differences from the wild type.",O Choi 2022,2022,5 genes,Choi-2022-Negatively Regulated Aerobactin and,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21889,PHI:124072,UniProt,A0A0H2XJA6,GenBank,sausa300_0301,,,,ScrA,,,,,,,1280,Staphylococcus aureus,,USA300 AH1263,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,brain; heart; lung; liver; kidney; spleen,small protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,37154710,PubMed,10.1128/spectrum.05255-22,Microbiol Spectr. 2023 Jun 15;11(3):e0525522. doi: 10.1128/spectrum.05255-22. Epub 2023 May 8,carrolr3@ohio.edu,"Compared to mice infected with the wild-type strain, scrA mutant-infected mice had decreased bacterial burdens in the heart, lungs, and liver, while there was no significant difference in the brain, kidneys, or spleen.",M A Wittekind 2023,2023,1 gene,Wittekind-2023-The Small Protein ScrA Influenc,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21890,PHI:124073,UniProt,A0A194VXX9,GenBank,KUI69101,,,03-8,CreA (KUI69101.1),chromosome 4,,,,,,105487,Valsa mali,,,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit; twig,DNA-binding protein cre-1,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37298203,PubMed,10.3390/ijms24119252,Int J Mol Sci. 2023 May 25;24(11):9252. doi: 10.3390/ijms24119252,chrli@sdau.edu.cn,Lengths of the lesions on the apple fruit with ΔVmCreA inoculations had decreased by approximately 53% and apple twigs were reduced by approximately 57% compared to those with the WT.,J Jin 2023,2023,1 gene,Jin-2023-The Regulation of the Growth and Path,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21891,PHI:124074,UniProt,Q59T95,GenBank,AOW25874,,,SC5314,cys4,chromosome 1,cys4Δ/Δ,,,,,5476,Candida albicans,,CAF2-1,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,cystathionine β-synthase,,,MAPK pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36525499,PubMed,10.1126/sciadv.add5366,Sci Adv. 2022 Dec 16;8(50):eadd5366. doi: 10.1126/sciadv.add5366. Epub 2022 Dec 16,changwenqiang@sdu.edu.cn,"Deletion of CBS leads to deficiencies in resistance to oxidative stress, retarded cell growth, defective hyphal growth and reduce the pathogenicity of C. albicans.",W Chang 2022,2022,1 gene,Chang-2022-Inhibition of fungal pathogenicity,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21892,PHI:124075,UniProt,G4NCW4,GenBank,EHA48357,,,70-15,PCT1(MGG_01003),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,phosphocholine cytidylyltransferase,,,phosphatidylethanolamine (PE) methylation pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37213497,PubMed,10.3389/fmicb.2023.1136168,Front Microbiol. 2023 May 5;14:1136168. doi: 10.3389/fmicb.2023.1136168. eCollection 2023,zhywang@zju.edu.cn,"Gene deletion mutant MoPCT1 was impaired in vegetative growth, conidiation and also in infectious growth and pathogenicity.",Z Xu 2023,2023,1 gene,Xu-2023-Phosphocholine cytidylyltransferase Mo,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21893,PHI:124075,UniProt,G4NCW4,GenBank,EHA48357,,,70-15,PCT1(MGG_01003),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,phosphocholine cytidylyltransferase,,,phosphatidylethanolamine (PE) methylation pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37213497,PubMed,10.3389/fmicb.2023.1136168,Front Microbiol. 2023 May 5;14:1136168. doi: 10.3389/fmicb.2023.1136168. eCollection 2023,zhywang@zju.edu.cn,"Gene deletion mutant MoPCT1 was impaired in vegetative growth, conidiation and also in infectious growth and pathogenicity.",Z Xu 2023,2023,1 gene,Xu-2023-Phosphocholine cytidylyltransferase Mo,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21894,PHI:124075,UniProt,G4NCW4,GenBank,EHA48357,,,70-15,PCT1(MGG_01003),chromosome 5,MoPct1ΔNLS,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,phosphocholine cytidylyltransferase,,,phosphatidylethanolamine (PE) methylation pathway,unaffected pathogenicity,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: partial,,,NN,37213497,PubMed,10.3389/fmicb.2023.1136168,Front Microbiol. 2023 May 5;14:1136168. doi: 10.3389/fmicb.2023.1136168. eCollection 2023,zhywang@zju.edu.cn,MoPct1ΔNLS-GFP were fully pathogenic to barley leaves.,Z Xu 2023,2023,1 gene,Xu-2023-Phosphocholine cytidylyltransferase Mo,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21895,PHI:124076,UniProt,Q9RGX0,GenBank,AAF21893,,,LO28,SpxA1,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),L929 cell line,,,fibroblast,transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36102657,PubMed,10.1128/iai.00211-22,Infect Immun. 2022 Oct 20;90(10):e0021122. doi: 10.1128/iai.00211-22. Epub 2022 Sep 14,reniere@uw.edu,Deletion of spxA1 decreased motility contributes to the virulence defect of DspxA1 cells in tissue culture infection models.,M R Cesinger 2022,2022,1 gene,Cesinger-2022-The Transcriptional Regulator Sp,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21896,PHI:124077,UniProt,A0A1D8PU37,GenBank,AOW31647,,,SC5314,Gnp2 (CR_09920W),chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,amino acid permease,,,amino acid pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35073760,PubMed,10.1128/mbio.03142-21,mBio. 2022 Feb 22;13(1):e0314221. doi: 10.1128/mbio.03142-21. Epub 2022 Jan 25,Slavena.Vylkova@leibniz-hki.de,Increased survival was visible for mice infected with the gnp2 deletion single mutant.,E Garbe 2022,2022,3 genes,Garbe-2022-GNP2 Encodes a High-Specificity Pro,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21897,PHI:124078,UniProt,Q59RL1,GenBank,AOW29982,,,SC5314,Gnp1,chromosome 6,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,amino acid permease,,,amino acid pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35073760,PubMed,10.1128/mbio.03142-21,mBio. 2022 Feb 22;13(1):e0314221. doi: 10.1128/mbio.03142-21. Epub 2022 Jan 25,Slavena.Vylkova@leibniz-hki.de,Increased survival was visible for mice infected with the gnp1deletion single mutant.,E Garbe 2022,2022,3 genes,Garbe-2022-GNP2 Encodes a High-Specificity Pro,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21898,PHI:124079,UniProt,A0A1D8PU34,GenBank,AOW31646,,,SC5314,Gnp3,chromosome R,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,amino acid permease,,,amino acid pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35073760,PubMed,10.1128/mbio.03142-21,mBio. 2022 Feb 22;13(1):e0314221. doi: 10.1128/mbio.03142-21. Epub 2022 Jan 25,Slavena.Vylkova@leibniz-hki.de,Increased survival was visible for mice infected with the gnp3 deletion single mutant.,E Garbe 2022,2022,3 genes,Garbe-2022-GNP2 Encodes a High-Specificity Pro,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21899,PHI:124078,UniProt,Q59RL1,GenBank,AOW29982,,,SC5314,Gnp1,chromosome 6,,,,,PHI:124077; PHI:124079,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,amino acid permease,,,amino acid pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35073760,PubMed,10.1128/mbio.03142-21,mBio. 2022 Feb 22;13(1):e0314221. doi: 10.1128/mbio.03142-21. Epub 2022 Jan 25,Slavena.Vylkova@leibniz-hki.de,wild type survival was visible for mice infected with the gnp3/gnp2/gnp1 deletion triple mutant.,E Garbe 2022,2022,3 genes,Garbe-2022-GNP2 Encodes a High-Specificity Pro,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21900,PHI:124077,UniProt,A0A1D8PU37,GenBank,AOW31647,,,SC5314,Gnp2 (CR_09920W),chromosome R,,,,,PHI:124078; PHI:124079,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,amino acid permease,,,amino acid pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35073760,PubMed,10.1128/mbio.03142-21,mBio. 2022 Feb 22;13(1):e0314221. doi: 10.1128/mbio.03142-21. Epub 2022 Jan 25,Slavena.Vylkova@leibniz-hki.de,wild type survival was visible for mice infected with the gnp3/gnp2/gnp1 deletion triple mutant.,E Garbe 2022,2022,3 genes,Garbe-2022-GNP2 Encodes a High-Specificity Pro,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21901,PHI:124079,UniProt,A0A1D8PU34,GenBank,AOW31646,,,SC5314,Gnp3,chromosome R,,,,,PHI:124077; PHI:124078,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,,amino acid permease,,,amino acid pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35073760,PubMed,10.1128/mbio.03142-21,mBio. 2022 Feb 22;13(1):e0314221. doi: 10.1128/mbio.03142-21. Epub 2022 Jan 25,Slavena.Vylkova@leibniz-hki.de,wild type survival was visible for mice infected with the gnp3/gnp2/gnp1 deletion triple mutant.,E Garbe 2022,2022,3 genes,Garbe-2022-GNP2 Encodes a High-Specificity Pro,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21902,PHI:124080,UniProt,A0A7G1JJ47,GenBank,BCK42533,,,DAT299,AdcA,,,,,,,1307,Streptococcus suis,,SC19,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; liver; spleen; lung; kidney; brain,Zn-binding lipoproteins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37212676,PubMed,10.1128/spectrum.04337-22,Microbiol Spectr. 2023 Jun 15;11(3):e0433722. doi: 10.1128/spectrum.04337-22. Epub 2023 May 22,beiwc@mail.hzau.edu.cn,Deletion of the adcA gene in S. suis resulted in a significant decrease in virulence.,M Peng 2023,2023,2 genes,Peng-2023-The adcA and lmb Genes Play an Impor,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21903,PHI:124081,UniProt,A0A7G1JL50,GenBank,BCK42722,,,DAT299,Lmb,,,,,,,1307,Streptococcus suis,,SC19,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; liver; spleen; lung; kidney; brain,Zn-binding lipoproteins,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37212676,PubMed,10.1128/spectrum.04337-22,Microbiol Spectr. 2023 Jun 15;11(3):e0433722. doi: 10.1128/spectrum.04337-22. Epub 2023 May 22,beiwc@mail.hzau.edu.cn,Deletion of the Lmb gene in S. suis resulted in a significant decrease in virulence.,M Peng 2023,2023,2 genes,Peng-2023-The adcA and lmb Genes Play an Impor,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21904,PHI:124080,UniProt,A0A7G1JJ47,GenBank,BCK42533,,,DAT299,AdcA,,,,,,PHI:124081,1307,Streptococcus suis,,SC19,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; liver; spleen; lung; kidney; brain,Zn-binding lipoproteins,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37212676,PubMed,10.1128/spectrum.04337-22,Microbiol Spectr. 2023 Jun 15;11(3):e0433722. doi: 10.1128/spectrum.04337-22. Epub 2023 May 22,beiwc@mail.hzau.edu.cn,"Survival rate of the ΔadcAΔlmb group was 100%, with mice showing no obvious clinical symptoms.",M Peng 2023,2023,2 genes,Peng-2023-The adcA and lmb Genes Play an Impor,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21905,PHI:124081,UniProt,A0A7G1JL50,GenBank,BCK42722,,,DAT299,Lmb,,,,,,PHI:124080,1307,Streptococcus suis,,SC19,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,heart; liver; spleen; lung; kidney; brain,Zn-binding lipoproteins,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37212676,PubMed,10.1128/spectrum.04337-22,Microbiol Spectr. 2023 Jun 15;11(3):e0433722. doi: 10.1128/spectrum.04337-22. Epub 2023 May 22,beiwc@mail.hzau.edu.cn,"Survival rate of the ΔadcAΔlmb group was 100%, with mice showing no obvious clinical symptoms.",M Peng 2023,2023,2 genes,Peng-2023-The adcA and lmb Genes Play an Impor,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21906,PHI:124082,UniProt,B0BS85,GenBank,ABY70242,,,JL03,FliY (APJL_1690),,,,,,PHI:124083,715,Actinobacillus pleuropneumoniae,,WF83,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,"amino acid ABC transporter, substrate-binding",,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37250053,PubMed,10.3389/fmicb.2023.1169774,Front Microbiol. 2023 May 12;14:1169774. doi: 10.3389/fmicb.2023.1169774. eCollection 2023,liujinlin2009@126.com,"Mice infected with the ΔfliY ΔydjN showed similar bacterial loads (logCFU/g, 6.82 ± 0.94), with those infected with A. pleuropneumoniae WT (logCFU/g, 7.37 ± 0.90; P-value > 0.05).",F Zhao 2023,2023,2 genes,Zhao-2023-Actinobacillus pleuropneumoniae FliY,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21907,PHI:124083,UniProt,B0BUG5,GenBank,ABY69170,,,JL03,YdjN (APJL_0600),,,,,,PHI:124082,715,Actinobacillus pleuropneumoniae,,WF83,pleuropneumonia (pig),rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,proton glutamate symport protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37250053,PubMed,10.3389/fmicb.2023.1169774,Front Microbiol. 2023 May 12;14:1169774. doi: 10.3389/fmicb.2023.1169774. eCollection 2023,liujinlin2009@126.com,"Mice infected with the ΔfliY ΔydjN showed similar bacterial loads (logCFU/g, 6.82 ± 0.94), with those infected with A. pleuropneumoniae WT (logCFU/g, 7.37 ± 0.90; P-value > 0.05).",F Zhao 2023,2023,2 genes,Zhao-2023-Actinobacillus pleuropneumoniae FliY,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21908,PHI:124082,UniProt,B0BS85,GenBank,ABY70242,,,JL03,FliY (APJL_1690),,,,,,PHI:124083,715,Actinobacillus pleuropneumoniae,,WF83,pleuropneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),,,,,"amino acid ABC transporter, substrate-binding",,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37250053,PubMed,10.3389/fmicb.2023.1169774,Front Microbiol. 2023 May 12;14:1169774. doi: 10.3389/fmicb.2023.1169774. eCollection 2023,liujinlin2009@126.com,"The input ratio of ΔfliYΔydjN to WT was calculated as 1.09, and the average output ratio was calculated to be 0.63. Thus, the average CI value between ΔfliYΔydjN and WF83 was 0.58, which was higher than the cutoff value (0.2) for attenuation. This result indicates that ΔfliYΔydjN was still virulent in pigs. Tissue type: piglets",F Zhao 2023,2023,2 genes,Zhao-2023-Actinobacillus pleuropneumoniae FliY,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21909,PHI:124083,UniProt,B0BUG5,GenBank,ABY69170,,,JL03,YdjN (APJL_0600),,,,,,PHI:124082,715,Actinobacillus pleuropneumoniae,,WF83,pleuropneumonia (pig),even-toed ungulates,9823,Sus scrofa (related: pig),C57Bl/6,,,,proton glutamate symport protein,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37250053,PubMed,10.3389/fmicb.2023.1169774,Front Microbiol. 2023 May 12;14:1169774. doi: 10.3389/fmicb.2023.1169774. eCollection 2023,liujinlin2009@126.com,"The input ratio of ΔfliYΔydjN to WT was calculated as 1.09, and the average output ratio was calculated to be 0.63. Thus, the average CI value between ΔfliYΔydjN and WF83 was 0.58, which was higher than the cutoff value (0.2) for attenuation. This result indicates that ΔfliYΔydjN was still virulent in pigs. Tissue type: piglets",F Zhao 2023,2023,2 genes,Zhao-2023-Actinobacillus pleuropneumoniae FliY,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21910,PHI:124084,,no data found,,,,,,FASII,,,,,,,1351,Enterococcus faecalis,226185,V583,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; kidney,type II fatty acid synthase,,,type II fatty acid synthesis pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,34309397,PubMed,10.1128/JB.00221-21,J Bacteriol. 2021 Sep 23;203(20):e0022121. doi: 10.1128/JB.00221-21. Epub 2021 Jul 26,agnes.fouet@inserm.fr,"Bacterial counts in liver, spleen, and kidneys, as well as organ weights, were similar for BWT-FASII- and EfΔFASII-infected mice at all time points.",C Hays 2021,2021,2 genes,Hays-2021-Type II fatty acid synthesis pathway,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21911,PHI:124085,UniProt,Q839G6,,,,,DAT299,cfa (ef0203),,,,,,,1351,Enterococcus faecalis,226185,V583,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,liver; spleen; kidney,cyclopropane fatty acid synthase,,,type II fatty acid synthesis pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,34309397,PubMed,10.1128/JB.00221-21,J Bacteriol. 2021 Sep 23;203(20):e0022121. doi: 10.1128/JB.00221-21. Epub 2021 Jul 26,agnes.fouet@inserm.fr,No differences were observed in terms of bacterial loads in the different organs between EfΔcfa- and BWT-cfa-infected mice.,C Hays 2021,2021,2 genes,Hays-2021-Type II fatty acid synthesis pathway,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21912,PHI:124086,UniProt,Q2FGH0,GenBank,ABD22195,,,USA300_FPR3757,sodA (SAUSA300_1513),,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,femur; kidney; liver; heart,superoxide dismutases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36877063,PubMed,10.1128/iai.00529-22,Infect Immun. 2023 Apr 18;91(4):e0052922. doi: 10.1128/iai.00529-22. Epub 2023 Mar 6,jim.cassat@vumc.org,sodA mutant exhibits attenuated survival in vitro in high glucose and in vivo during osteomyelitis in hyperglycemic mice.,C E Butrico 2023,2023,2 genes,Butrico-2023-Hyperglycemia Increases Severity,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21913,PHI:124087,UniProt,Q2G261,GenBank,AAG44813,,,RN6390,sodM,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,femur; kidney; liver; heart,superoxide dismutases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36877063,PubMed,10.1128/iai.00529-22,Infect Immun. 2023 Apr 18;91(4):e0052922. doi: 10.1128/iai.00529-22. Epub 2023 Mar 6,jim.cassat@vumc.org,sodM mutant exhibits attenuated survival in vitro in high glucose and in vivo during osteomyelitis in hyperglycemic mice.,C E Butrico 2023,2023,2 genes,Butrico-2023-Hyperglycemia Increases Severity,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21914,PHI:124086,UniProt,Q2FGH0,GenBank,ABD22195,,,USA300_FPR3757,sodA (SAUSA300_1513),,,,,,PHI:124087,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,femur; kidney; liver; heart,superoxide dismutases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36877063,PubMed,10.1128/iai.00529-22,Infect Immun. 2023 Apr 18;91(4):e0052922. doi: 10.1128/iai.00529-22. Epub 2023 Mar 6,jim.cassat@vumc.org,sodA sodM mutants had significantly less weight loss at multiple days postinfection compared to mice infected with WT,C E Butrico 2023,2023,2 genes,Butrico-2023-Hyperglycemia Increases Severity,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21915,PHI:124087,UniProt,Q2G261,GenBank,AAG44813,,,RN6390,sodM,,,,,,PHI:124086,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,femur; kidney; liver; heart,superoxide dismutases,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36877063,PubMed,10.1128/iai.00529-22,Infect Immun. 2023 Apr 18;91(4):e0052922. doi: 10.1128/iai.00529-22. Epub 2023 Mar 6,jim.cassat@vumc.org,sodA sodM mutants had significantly less weight loss at multiple days postinfection compared to mice infected with WT,C E Butrico 2023,2023,2 genes,Butrico-2023-Hyperglycemia Increases Severity,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21916,PHI:124086,UniProt,Q2FGH0,GenBank,ABD22195,,,USA300_FPR3757,sodA (SAUSA300_1513),,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,femur; kidney; liver; heart,superoxide dismutases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36877063,PubMed,10.1128/iai.00529-22,Infect Immun. 2023 Apr 18;91(4):e0052922. doi: 10.1128/iai.00529-22. Epub 2023 Mar 6,jim.cassat@vumc.org,sodA mutant-infected euglycemic mice showed no differences in burdens in the infected femurs at day 14 postinfection.,C E Butrico 2023,2023,2 genes,Butrico-2023-Hyperglycemia Increases Severity,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21917,PHI:124087,UniProt,Q2G261,GenBank,AAG44813,,,RN6390,sodM,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,femur; kidney; liver; heart,superoxide dismutases,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,36877063,PubMed,10.1128/iai.00529-22,Infect Immun. 2023 Apr 18;91(4):e0052922. doi: 10.1128/iai.00529-22. Epub 2023 Mar 6,jim.cassat@vumc.org,sodM mutant-infected euglycemic mice showed no differences in burdens in the infected femurs at day 14 postinfection.,C E Butrico 2023,2023,2 genes,Butrico-2023-Hyperglycemia Increases Severity,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21918,PHI:124088,,no data found,GenBank,ATG95625,,,,YppAc,,,,,,,80869,Paracidovorax citrulli,,KACC17005,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),,,,seedling; leaf,yggS family pyridoxal phosphate-dependent enzyme,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene mutation,,,NN,37291764,PubMed,10.5423/PPJ.OA.03.2023.0050,Plant Pathol J. 2023 Jun;39(3):235-244. doi: 10.5423/PPJ.OA.03.2023.0050. Epub 2023 Jun 1,swhan@cau.ac.kr,"All watermelon seedlings infected by Ac(EV) and AcΔyppAc(YppAc) exhibited typical disease symptoms, and the disease index reached two 7 days post-inoculation.",L Heo 2023,2023,1 gene,Heo-2023-Proteomic and Phenotypic Analyses of,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21919,PHI:124089,UniProt,A6SDT7,GenBank,EDN31869,,,B05.10,Mca1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,metacaspase gene,,,metacaspase-dependent pathway,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,37191530,PubMed,10.1128/spectrum.00526-23,Microbiol Spectr. 2023 Jun 15;11(3):e0052623. doi: 10.1128/spectrum.00526-23. Epub 2023 May 16,wliang790625@163.com,Deletion of BcMca1 shows wild type pathogenicity with or without Perillaldehyde treatment.,G Wang 2023,2023,2 genes,Wang-2023-Perillaldehyde Functions as a Potent,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21920,PHI:124090,,no data found,,,,,,Mca2,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,metacaspase gene,,,metacaspase-dependent pathway,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,37191530,PubMed,10.1128/spectrum.00526-23,Microbiol Spectr. 2023 Jun 15;11(3):e0052623. doi: 10.1128/spectrum.00526-23. Epub 2023 May 16,wliang790625@163.com,Deletion of BcMca2 shows wild type pathogenicity with or without Perillaldehyde treatment.,G Wang 2023,2023,2 genes,Wang-2023-Perillaldehyde Functions as a Potent,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21921,PHI:124089,UniProt,A6SDT7,GenBank,EDN31869,,,B05.10,Mca1,,,,,,PHI:124090,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,metacaspase gene,,,metacaspase-dependent pathway,reduced virulence,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,37191530,PubMed,10.1128/spectrum.00526-23,Microbiol Spectr. 2023 Jun 15;11(3):e0052623. doi: 10.1128/spectrum.00526-23. Epub 2023 May 16,wliang790625@163.com,Deletion of BcMca1Mca2 mutant showed reduced pathogenicity with or without Perillaldehyde treatment compared to the single-gene mutants and B05.10.,G Wang 2023,2023,2 genes,Wang-2023-Perillaldehyde Functions as a Potent,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21922,PHI:124090,,no data found,,,,,,Mca2,,,,,,PHI:124089,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,leaf,metacaspase gene,,,metacaspase-dependent pathway,reduced virulence,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,37191530,PubMed,10.1128/spectrum.00526-23,Microbiol Spectr. 2023 Jun 15;11(3):e0052623. doi: 10.1128/spectrum.00526-23. Epub 2023 May 16,wliang790625@163.com,Deletion of BcMca1Mca2 mutant showed reduced pathogenicity with or without Perillaldehyde treatment compared to the single-gene mutants and B05.10.,G Wang 2023,2023,2 genes,Wang-2023-Perillaldehyde Functions as a Potent,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21923,PHI:124091,UniProt,N4UTF2,GenBank,TDZ17043,,,104-T,AlcOx,,,,,,,5465,Colletotrichum orbiculare,1213857,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,alcohol oxidases,,,,reduced virulence,,,yes,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36542709,PubMed,10.1126/sciadv.ade9982,Sci Adv. 2022 Dec 21;8(51):eade9982. doi: 10.1126/sciadv.ade9982. Epub 2022 Dec 21,yasuyuki.kubo@setsunan.ac.jp,Cucumber cotyledons showed that fewer and smaller lesions were formed by all the mutants compared to the wild-type strains.,B Bissaro 2022,2022,2 genes,Bissaro-2022-Tandem metalloenzymes gate plant,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21924,PHI:124092,UniProt,N4UUY4,GenBank,TDZ17044,,,104-T,Perox,,,,,,,5465,Colletotrichum orbiculare,1213857,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,peroxidase,,,,reduced virulence,,,yes,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,36542709,PubMed,10.1126/sciadv.ade9982,Sci Adv. 2022 Dec 21;8(51):eade9982. doi: 10.1126/sciadv.ade9982. Epub 2022 Dec 21,yasuyuki.kubo@setsunan.ac.jp,Cucumber cotyledons showed that fewer and smaller lesions were formed by all the mutants compared to the wild-type strains.,B Bissaro 2022,2022,2 genes,Bissaro-2022-Tandem metalloenzymes gate plant,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21925,PHI:124091,UniProt,N4UTF2,GenBank,TDZ17043,,,104-T,AlcOx,,,,,,PHI:124092,5465,Colletotrichum orbiculare,1213857,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,alcohol oxidases,,,,reduced virulence,,,yes,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36542709,PubMed,10.1126/sciadv.ade9982,Sci Adv. 2022 Dec 21;8(51):eade9982. doi: 10.1126/sciadv.ade9982. Epub 2022 Dec 21,yasuyuki.kubo@setsunan.ac.jp,Cucumber cotyledons showed that fewer and smaller lesions were formed by all the mutants compared to the wild-type strains.,B Bissaro 2022,2022,2 genes,Bissaro-2022-Tandem metalloenzymes gate plant,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21926,PHI:124092,UniProt,N4UUY4,GenBank,TDZ17044,,,104-T,Perox,,,,,,PHI:124091,5465,Colletotrichum orbiculare,1213857,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,peroxidase,,,,reduced virulence,,,yes,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,36542709,PubMed,10.1126/sciadv.ade9982,Sci Adv. 2022 Dec 21;8(51):eade9982. doi: 10.1126/sciadv.ade9982. Epub 2022 Dec 21,yasuyuki.kubo@setsunan.ac.jp,Cucumber cotyledons showed that fewer and smaller lesions were formed by all the mutants compared to the wild-type strains.,B Bissaro 2022,2022,2 genes,Bissaro-2022-Tandem metalloenzymes gate plant,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21927,PHI:124091,UniProt,N4UTF2,GenBank,TDZ17043,,,104-T,AlcOx,,,,,,,5465,Colletotrichum orbiculare,1213857,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,alcohol oxidases,,,,unaffected pathogenicity,,,yes,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36542709,PubMed,10.1126/sciadv.ade9982,Sci Adv. 2022 Dec 21;8(51):eade9982. doi: 10.1126/sciadv.ade9982. Epub 2022 Dec 21,yasuyuki.kubo@setsunan.ac.jp,Addition of n-octadecanal partially restored appressorium penetration ability and lesion formation of mutant on cucumber leaves,B Bissaro 2022,2022,2 genes,Bissaro-2022-Tandem metalloenzymes gate plant,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21928,PHI:124092,UniProt,N4UUY4,GenBank,TDZ17044,,,104-T,Perox,,,,,,,5465,Colletotrichum orbiculare,1213857,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,peroxidase,,,,unaffected pathogenicity,,,yes,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,36542709,PubMed,10.1126/sciadv.ade9982,Sci Adv. 2022 Dec 21;8(51):eade9982. doi: 10.1126/sciadv.ade9982. Epub 2022 Dec 21,yasuyuki.kubo@setsunan.ac.jp,Addition of n-octadecanal partially restored appressorium penetration ability and lesion formation of mutant on cucumber leaves,B Bissaro 2022,2022,2 genes,Bissaro-2022-Tandem metalloenzymes gate plant,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21929,PHI:124091,UniProt,N4UTF2,GenBank,TDZ17043,,,104-T,AlcOx,,,,,,PHI:124092,5465,Colletotrichum orbiculare,1213857,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,alcohol oxidases,,,,unaffected pathogenicity,,,yes,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,36542709,PubMed,10.1126/sciadv.ade9982,Sci Adv. 2022 Dec 21;8(51):eade9982. doi: 10.1126/sciadv.ade9982. Epub 2022 Dec 21,yasuyuki.kubo@setsunan.ac.jp,Addition of n-octadecanal partially restored appressorium penetration ability and lesion formation of mutant on cucumber leaves,B Bissaro 2022,2022,2 genes,Bissaro-2022-Tandem metalloenzymes gate plant,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21930,PHI:124092,UniProt,N4UUY4,GenBank,TDZ17044,,,104-T,Perox,,,,,,PHI:124091,5465,Colletotrichum orbiculare,1213857,104-T,anthracnose (Cucurbitaceae),eudicots,3659,Cucumis sativus (related: cucumber),cv. Suyo,,,cotyledon,peroxidase,,,,unaffected pathogenicity,,,yes,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,36542709,PubMed,10.1126/sciadv.ade9982,Sci Adv. 2022 Dec 21;8(51):eade9982. doi: 10.1126/sciadv.ade9982. Epub 2022 Dec 21,yasuyuki.kubo@setsunan.ac.jp,Addition of n-octadecanal partially restored appressorium penetration ability and lesion formation of mutant on cucumber leaves,B Bissaro 2022,2022,2 genes,Bissaro-2022-Tandem metalloenzymes gate plant,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21931,PHI:124093,UniProt,A1TM68,GenBank,ABM32056,,,AAC00-1,Hcp,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 2,,,seedling,type Ⅵ secretion system,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37288971,PubMed,10.1128/mbio.00459-23,mBio. 2023 Jun 8:e0045923. doi: 10.1128/mbio.00459-23. Online ahead of print,dongt@sustech.edu.cn.,"T6SS-null strain Δhcp, was still able to induce BFB in plants, with no significant difference from the WT strain.",Y Kan 2023,2023,3 genes,Kan-2023-Differential plant cell responses to,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21932,PHI:124094,,no data found,,,,,,tssM,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 2,,,seedling,type Ⅵ secretion system,,,MAPK signaling pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37288971,PubMed,10.1128/mbio.00459-23,mBio. 2023 Jun 8:e0045923. doi: 10.1128/mbio.00459-23. Online ahead of print,dongt@sustech.edu.cn.,"T6SS-null strain ΔtssM, was still able to induce BFB in plants, with no significant difference from the WT strain.",Y Kan 2023,2023,3 genes,Kan-2023-Differential plant cell responses to,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21933,PHI:124095,,no data found,,,,,,hrcC,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 2,,,seedling,type Ⅲ secretion system,,,MAPK signaling pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37288971,PubMed,10.1128/mbio.00459-23,mBio. 2023 Jun 8:e0045923. doi: 10.1128/mbio.00459-23. Online ahead of print,dongt@sustech.edu.cn.,T3SS-null strain ΔhrcC does not cause any BFB symptoms in plants,Y Kan 2023,2023,3 genes,Kan-2023-Differential plant cell responses to,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21934,PHI:124094,,no data found,,,,,,tssM,,,,,,PHI:124095,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 2,,,seedling,type Ⅵ secretion system,,,MAPK signaling pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37288971,PubMed,10.1128/mbio.00459-23,mBio. 2023 Jun 8:e0045923. doi: 10.1128/mbio.00459-23. Online ahead of print,dongt@sustech.edu.cn.,T3SS/T6SS double-deletion strain (ΔhrcCΔtssM) could not cause any BFB symptoms in plants,Y Kan 2023,2023,3 genes,Kan-2023-Differential plant cell responses to,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21935,PHI:124095,,no data found,,,,,,hrcC,,,,,,PHI:124094,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 2,,,seedling,type Ⅲ secretion system,,,MAPK signaling pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37288971,PubMed,10.1128/mbio.00459-23,mBio. 2023 Jun 8:e0045923. doi: 10.1128/mbio.00459-23. Online ahead of print,dongt@sustech.edu.cn.,T3SS/T6SS double-deletion strain (ΔhrcCΔtssM) could not cause any BFB symptoms in plants,Y Kan 2023,2023,3 genes,Kan-2023-Differential plant cell responses to,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21936,PHI:124093,UniProt,A1TM68,GenBank,ABM32056,,,AAC00-1,Hcp,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 2,,,seedling,type Ⅵ secretion system,,,MAPK signaling pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37288971,PubMed,10.1128/mbio.00459-23,mBio. 2023 Jun 8:e0045923. doi: 10.1128/mbio.00459-23. Online ahead of print,dongt@sustech.edu.cn.,survival of Δhcp significantly decreased compared to the wild type when coincubated with the mixed bacteria (A. citrulli (Ac) mixed with the phyllosphere bacteria).,Y Kan 2023,2023,3 genes,Kan-2023-Differential plant cell responses to,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21937,PHI:124094,,no data found,,,,,,tssM,,,,,,,80869,Paracidovorax citrulli,397945,AAC00-1,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 2,,,seedling,type Ⅵ secretion system,,,MAPK signaling pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37288971,PubMed,10.1128/mbio.00459-23,mBio. 2023 Jun 8:e0045923. doi: 10.1128/mbio.00459-23. Online ahead of print,dongt@sustech.edu.cn.,survival of ΔtssM significantly decreased compared to the wild type when coincubated with the mixed bacteria (A. citrulli (Ac) mixed with the phyllosphere bacteria).,Y Kan 2023,2023,3 genes,Kan-2023-Differential plant cell responses to,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21938,PHI:124096,UniProt,N1RSS1,GenBank,EMT68949,,,race 4,sp9 (EMT68949.1),chromosome unknown,,,,,,5507,Fusarium oxysporum,,f. sp. cubense race 4 isolate B2,Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),cv. Brazilian,,,rhizome,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,wild type,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35108093,PubMed,10.1128/AEM.00604-21,Appl Environ Microbiol. 2022 Mar 22;88(6):e0060421. doi: 10.1128/AEM.00604-21. Epub 2022 Feb 2,heartone@126.com,"The fosp9 disruptants displayed a significant reduction in producing wilt symptoms on bananas, indicating that fosp9 is essential for the full virulence of this pathogen for banana.",L Guo 2022,2022,1 gene,"Guo-2022-Fosp9, a novel secreted protein, is e",BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21939,PHI:124097,UniProt,A0A380IN75,GenBank,SUN09924,,,NCTC6175,Cas9,,,,,,,1311,Streptococcus agalactiae,205921; 1427374,A909; CNCTC 10/84,neonatal pneumonia; neonatal meningitis; bovine mastitis; meningoencephalitis (fish),rodents,10090,Mus musculus (related: house mouse),BALB/cJ,,,blood; lung; spleen,type II-A CRISPR-cas9 system,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37296208,PubMed,10.1038/s42003-023-04994-w,Commun Biol. 2023 Jun 9;6(1):620. doi: 10.1038/s42003-023-04994-w,thomas.hooven@chp.edu,No virulence changes in a mouse model of sepsis compared with wild type.,K P Gopalakrishna 2023,2023,1 gene,Gopalakrishna-2023-Group B Streptococcus Cas9,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21940,PHI:124098,UniProt,P53867,GenBank,EJP61110,,,ARSEF 2860,Atg4,chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,autophagy-related gene 4,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full; gene complementation,,,NN,37233254,PubMed,10.3390/jof9050543,J Fungi (Basel). 2023 May 6;9(5):543. doi: 10.3390/jof9050543,0621538@zju.edu.cn,Disruption of BbATG4 resulted in significantly weakened virulence in topical and intrahemocoel injection assays.,J L Ding 2023,2023,9 genes,Ding-2023-Autophagy-Related Gene 4 Participate,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21941,PHI:124099,UniProt,J4W0G2,GenBank,EJP64020,,,ARSEF 2860,Atg1,chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,autophagy-related gene 1,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37233254,PubMed,10.3390/jof9050543,J Fungi (Basel). 2023 May 6;9(5):543. doi: 10.3390/jof9050543,0621538@zju.edu.cn,The LT50 values of ΔBbatg1 was delayed to 4 days.,J L Ding 2023,2023,9 genes,Ding-2023-Autophagy-Related Gene 4 Participate,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21942,PHI:124100,UniProt,A0A2N6NAN0,GenBank,PMB64333,,,JEF-007,Atg3,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,autophagy-related gene 3,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37233254,PubMed,10.3390/jof9050543,J Fungi (Basel). 2023 May 6;9(5):543. doi: 10.3390/jof9050543,0621538@zju.edu.cn,The LT50 values of ΔBbatg3 was delayed to 4 days.,J L Ding 2023,2023,9 genes,Ding-2023-Autophagy-Related Gene 4 Participate,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21943,PHI:124101,UniProt,J5JH39,GenBank,AET98917,,,,Atg5,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,autophagy-related gene 5,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37233254,PubMed,10.3390/jof9050543,J Fungi (Basel). 2023 May 6;9(5):543. doi: 10.3390/jof9050543,0621538@zju.edu.cn,The LT50 values of ΔBbatg5 was delayed to 4 days.,J L Ding 2023,2023,9 genes,Ding-2023-Autophagy-Related Gene 4 Participate,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21944,PHI:124102,UniProt,A0A2N6NWJ6,GenBank,PMB71651,,,JEF-007,Atg7,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,autophagy-related gene 7,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37233254,PubMed,10.3390/jof9050543,J Fungi (Basel). 2023 May 6;9(5):543. doi: 10.3390/jof9050543,0621538@zju.edu.cn,The LT50 values of ΔBbatg7 was delayed to 4 days.,J L Ding 2023,2023,9 genes,Ding-2023-Autophagy-Related Gene 4 Participate,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21945,PHI:124103,UniProt,J4UTT5,GenBank,EJP69267,,,ARSEF 2860,Atg8,chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,autophagy-related gene 8,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37233254,PubMed,10.3390/jof9050543,J Fungi (Basel). 2023 May 6;9(5):543. doi: 10.3390/jof9050543,0621538@zju.edu.cn,The LT50 values of ΔBbatg8 was delayed to 4.5 days.,J L Ding 2023,2023,9 genes,Ding-2023-Autophagy-Related Gene 4 Participate,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21946,PHI:124104,UniProt,A0A0A2VNK3,GenBank,KGQ09486,,,D1-5,Atg10,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,autophagy-related gene 10,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37233254,PubMed,10.3390/jof9050543,J Fungi (Basel). 2023 May 6;9(5):543. doi: 10.3390/jof9050543,0621538@zju.edu.cn,The LT50 values of ΔBbatg10 was delayed to 4 days.,J L Ding 2023,2023,9 genes,Ding-2023-Autophagy-Related Gene 4 Participate,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21947,PHI:124105,UniProt,A0A2N6NDE8,GenBank,PMB65288,,,JEF-007,Atg12,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,autophagy-related gene 12,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37233254,PubMed,10.3390/jof9050543,J Fungi (Basel). 2023 May 6;9(5):543. doi: 10.3390/jof9050543,0621538@zju.edu.cn,The LT50 values of ΔBbatg12 was delayed to 4 days.,J L Ding 2023,2023,9 genes,Ding-2023-Autophagy-Related Gene 4 Participate,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21948,PHI:124106,UniProt,A0A2N6NZW9,GenBank,PMB72808,,,JEF-007,Atg16,,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,autophagy-related gene 16,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37233254,PubMed,10.3390/jof9050543,J Fungi (Basel). 2023 May 6;9(5):543. doi: 10.3390/jof9050543,0621538@zju.edu.cn,The LT50 values of ΔBbatg16 was delayed to 4 days.,J L Ding 2023,2023,9 genes,Ding-2023-Autophagy-Related Gene 4 Participate,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21949,PHI:124107,UniProt,A0A7U1CPN7,GenBank,CP110673,,,,ModA (CP110673),,,,,,,584,Proteus mirabilis,,DP2019,urinary tract infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,Bladder,the molybdate-binding protein,,,flagellar assembly pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37180242,PubMed,10.3389/fmicb.2023.1156273,Front Microbiol. 2023 Apr 27;14:1156273. doi: 10.3389/fmicb.2023.1156273. eCollection 2023,dxyzgy@163.com,The modA mutant of Proteus mirabilis shows reduced virulence and tissue damage in a murine UTI model.,Y Huang 2023,2023,1 gene,Huang-2023-The molybdate-binding protein ModA,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21950,PHI:124108,,no data found,,,,,,CASFJ_18279,,,,,,,702518,Colletotrichum asianum,,FJ11-1,anthracnose,eudicots,29780,Mangifera indica (related: mango),cv. Tainong,,,leaf; fruit,mini-chromosomes,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37283539,PubMed,10.1128/mbio.00629-23,mBio. 2023 Jun 7:e0062923. doi: 10.1128/mbio.00629-23. Online ahead of print,65615384@qq.com,"All three mutants (ΔCASFJ_18279-19, ΔCASFJ_18279-22, and ΔCASFJ_18279-33) showed reduced aggressiveness compared to wild-type on both mango leaves and fruit.",H Wang 2023,2023,1 gene,Wang-2023-The evolution of mini-chromosomes in,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21951,PHI:124109,UniProt,I1S8E2,,,,,,EXOSC1 (FGSG_13120),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,RNA exosome complex,,,,reduced virulence,,,,,smaller lesions,reduced,reduced,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37158744,PubMed,10.1128/spectrum.05058-22,Microbiol Spectr. 2023 Jun 15;11(3):e0505822. doi: 10.1128/spectrum.05058-22. Epub 2023 May 9,jiezhou@fafu.edu.cn,"""The average disease indices (number of diseased spikelets per head) of the ΔFgexosc1 mutant is 1.42 while the wild-type strain PH-1 and ΔFgexosc1-C strain have indices of 13.44 and 13.00.""",Y Yuan 2023,2023,2 genes,Yuan-2023-Genome-Wide Characterization of the,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21952,PHI:124110,UniProt,A0A098DEC2,,,,,,EXOSCA (FGSG_08866),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,RNA exosome complex,,,,reduced virulence,,,,,smaller lesions,wild type,wild type,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37158744,PubMed,10.1128/spectrum.05058-22,Microbiol Spectr. 2023 Jun 15;11(3):e0505822. doi: 10.1128/spectrum.05058-22. Epub 2023 May 9,jiezhou@fafu.edu.cn,"""The average disease indices (number of diseased spikelets per head) of the ΔFgexoscA mutant is 4.74 while the wild-type strain PH-1 and ΔFgexoscA-C strain have indices of 13.44 and 13.33.""",Y Yuan 2023,2023,2 genes,Yuan-2023-Genome-Wide Characterization of the,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21953,PHI:124111,UniProt,A0A0D1E4Q7,GenBank,KIS70656,,,521,Cpl1,chromosome 3,,,,,,5270,Ustilago maydis,559306,FB1 × FB2,smut,monocots,4577,Zea mays (related: maize),,,,leaf,cerato-platanin-like protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37171083,PubMed,10.1111/mpp.13349,Mol Plant Pathol. 2023 Jul;24(7):768-787. doi: 10.1111/mpp.13349. Epub 2023 May 12,altegoer@hhu.de,We cannot see any significant phenotypic differences in disease symptoms between plants infected with FB1 × FB2 and plants infected with FB1Δcpl1 × FB2Δcpl1.,P Weiland 2023,2023,1 gene,Weiland-2023-Structural and functional analysi,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21954,PHI:124111,UniProt,A0A0D1E4Q7,GenBank,KIS70656,,,521,Cpl1,chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),,,,leaf,cerato-platanin-like protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37171083,PubMed,10.1111/mpp.13349,Mol Plant Pathol. 2023 Jul;24(7):768-787. doi: 10.1111/mpp.13349. Epub 2023 May 12,altegoer@hhu.de,we can detect subtle differences in the virulence of strains deleted for cpl1 compared to the respective parental strains.,P Weiland 2023,2023,1 gene,Weiland-2023-Structural and functional analysi,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21955,PHI:124112,UniProt,A0A2S4MTJ6,GenBank,AAP15940,,,2457T,AcrA,,,,,,PHI:124113,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,epithelial cell,tripartite complex,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37238693,PubMed,10.3390/biom13050823,Biomolecules. 2023 May 11;13(5):823. doi: 10.3390/biom13050823,martina.pasqua@uniroma1.it,Deletion of both acrA and acrB genes causes reduced survival of S. flexneri M90T strain within Caco-2 epithelial cells and prevents cell-to-cell spread of the bacteria.,M Coluccia 2023,2023,3 genes,Coluccia-2023-Role of the MDR Efflux Pump AcrA,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21956,PHI:124113,UniProt,A0A0H2UYQ5,GenBank,AAN42062,,,301,AcrB,,,,,,PHI:124112,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,epithelial cell,tripartite complex,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37238693,PubMed,10.3390/biom13050823,Biomolecules. 2023 May 11;13(5):823. doi: 10.3390/biom13050823,martina.pasqua@uniroma1.it,Deletion of both acrA and acrB genes causes reduced survival of S. flexneri M90T strain within Caco-2 epithelial cells and prevents cell-to-cell spread of the bacteria.,M Coluccia 2023,2023,3 genes,Coluccia-2023-Role of the MDR Efflux Pump AcrA,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21957,PHI:124112,UniProt,A0A2S4MTJ6,GenBank,AAP15940,,,2457T,AcrA,,,,,,PHI:124113,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,tripartite complex,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37238693,PubMed,10.3390/biom13050823,Biomolecules. 2023 May 11;13(5):823. doi: 10.3390/biom13050823,martina.pasqua@uniroma1.it,Lack of AcrAB EP poorly affects the viability of M90T when inside macrophage the proportion of dead bacteria detected at each time point was very similar either for the wild-type or mutant strain.,M Coluccia 2023,2023,3 genes,Coluccia-2023-Role of the MDR Efflux Pump AcrA,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21958,PHI:124113,UniProt,A0A0H2UYQ5,GenBank,AAN42062,,,301,AcrB,,,,,,PHI:124112,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,tripartite complex,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37238693,PubMed,10.3390/biom13050823,Biomolecules. 2023 May 11;13(5):823. doi: 10.3390/biom13050823,martina.pasqua@uniroma1.it,Lack of AcrAB EP poorly affects the viability of M90T when inside macrophage the proportion of dead bacteria detected at each time point was very similar either for the wild-type or mutant strain.,M Coluccia 2023,2023,3 genes,Coluccia-2023-Role of the MDR Efflux Pump AcrA,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21959,PHI:124112,UniProt,A0A2S4MTJ6,GenBank,AAP15940,,,2457T,AcrA,,,,,,,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,epithelial cell,tripartite complex,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37238693,PubMed,10.3390/biom13050823,Biomolecules. 2023 May 11;13(5):823. doi: 10.3390/biom13050823,martina.pasqua@uniroma1.it,Deletion of acrA gene causes reduced survival of S. flexneri M90T strain within Caco-2 epithelial cells and prevents cell-to-cell spread of the bacteria.,M Coluccia 2023,2023,3 genes,Coluccia-2023-Role of the MDR Efflux Pump AcrA,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21960,PHI:124113,UniProt,A0A0H2UYQ5,GenBank,AAN42062,,,301,AcrB,,,,,,,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,epithelial cell,tripartite complex,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37238693,PubMed,10.3390/biom13050823,Biomolecules. 2023 May 11;13(5):823. doi: 10.3390/biom13050823,martina.pasqua@uniroma1.it,"The percentage of M90T ΔacrB pSfacrB Δ408A PI-positive bacteria was very similar to the wild-type at very early stage of the infection, while it significantly increased in the following hours of infection.",M Coluccia 2023,2023,3 genes,Coluccia-2023-Role of the MDR Efflux Pump AcrA,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21961,PHI:124114,UniProt,A0A0H2V123,GenBank,AAN44015,,,301,AcrD,,,,,,,623,Shigella flexneri,1086030,M90T,shigellosis,primates,9606,Homo sapiens (related: human),Caco-2 cell line,,,epithelial cell,tripartite complex,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37238693,PubMed,10.3390/biom13050823,Biomolecules. 2023 May 11;13(5):823. doi: 10.3390/biom13050823,martina.pasqua@uniroma1.it,The proportion of PI-positive M90T ΔacrD bacteria was very similar to that of the parental strain at each time point analyzed.,M Coluccia 2023,2023,3 genes,Coluccia-2023-Role of the MDR Efflux Pump AcrA,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21962,PHI:124115,UniProt,A0A2S4VJV6,GenBank,POW09832,,,93-210,Chia1,,,,,,,27350,Puccinia striiformis,,f. sp. tritici strain CYR31,yellow rust,monocots,4565,Triticum aestivum (related: bread wheat),,,,leaf,chitin-binding type-3 domain-containing protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37175921,PubMed,10.3390/ijms24098215,Int J Mol Sci. 2023 May 4;24(9):8215. doi: 10.3390/ijms24098215,,The silencing of PstChia1 revealed that PstChia1 limited the growth and reduced the virulence of Pst.,J Guo 2023,2023,1 gene,"Guo-2023-Silencing a Chitinase Gene, PstChia1",BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21963,PHI:124116,UniProt,Q8ZRJ9,GenBank,AAL19263,,,LT2,STM0306 (NP_459304.1),,,,,,,28901,Salmonella enterica,90371,serovar Typhimurium,salmonellosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,outer membrane protein,,,NF-κB signaling pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37175877,PubMed,10.3390/ijms24098170,Int J Mol Sci. 2023 May 3;24(9):8170. doi: 10.3390/ijms24098170,wangweiwei@scau.edu.cn,"The deletion of the STM0306 gene led to reduced pathogenicity of S. Typhimurium, as evidenced by lower fecal bacterial counts and reduced body weight loss in S. Typhimurium infected mice.",C Ling 2023,2023,1 gene,Ling-2023-A Potential Adhesin_Invasin STM0306,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21964,PHI:124117,UniProt,G4N014,GenBank,EHA52252,,,70-15,Acb1 (MGG_06177),chromosome 3,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4513,Hordeum vulgare (related: barley),,,,leaf,acyl-CoA binding protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37187543,PubMed,10.3389/fmicb.2023.1179536,Front Microbiol. 2023 Apr 28;14:1179536. doi: 10.3389/fmicb.2023.1179536. eCollection 2023,21616143@zju.edu.cn,"Disruption of MoACB1 causes delayed hyphal growth, significant reduction in conidial production and delayed appressorium development and reduced pathogenicity.",N Cao 2023,2023,1 gene,Cao-2023-Acyl-coenzyme A binding protein MoAcb,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21965,PHI:124117,UniProt,G4N014,GenBank,EHA52252,,,70-15,Acb1 (MGG_06177),chromosome 3,,,,,,318829,Magnaporthe oryzae,,70-15,blast (rice),monocots,4530,Oryza sativa (related: rice),,,,leaf,acyl-CoA binding protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37187543,PubMed,10.3389/fmicb.2023.1179536,Front Microbiol. 2023 Apr 28;14:1179536. doi: 10.3389/fmicb.2023.1179536. eCollection 2023,21616143@zju.edu.cn,"Disruption of MoACB1 causes delayed hyphal growth, significant reduction in conidial production and delayed appressorium development and reduced pathogenicity.",N Cao 2023,2023,1 gene,Cao-2023-Acyl-coenzyme A binding protein MoAcb,BATCH_123A,2023-06-01,MC,,,,,,,,,,,,,
,,Record 21966,PHI:124118,UniProt,A0A7U7JFJ7,GenBank,CEJ17786,,,IPO1609,RipD,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278116,PubMed,10.1111/mpp.13360,Mol Plant Pathol. 2023 Jun 5. doi: 10.1111/mpp.13360. Online ahead of print,alberto.macho@psc.ac.cn,ΔripD mutant strain showed a significant virulence attenuation compared to GMI1000,K Wang 2023,2023,1 gene,Wang-2023-A bacterial type III effector target,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21967,PHI:124119,UniProt,A3RYZ9,GenBank,EAP71271,,,UW551,RipBT (RRSL_00703),,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. E-Potato 3,,,,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37154802,PubMed,10.1111/mpp.13342,Mol Plant Pathol. 2023 May 8. doi: 10.1111/mpp.13342. Online ahead of print,chenhuilan@mail.hzau.edu.cn,Mutation of RipBT in R. solanacearum showed attenuated virulence on potato,H Qiu 2023,2023,1 gene,Qiu-2023-A novel effector RipBT contributes to,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21968,PHI:124120,UniProt,Q8PHH6,GenBank,AAM38122,,,306,bluf2 (XAC3278),,,,,,,346,Xanthomonas citri,611301,99-1330,canker (Citrus),eudicots,2711,Citrus sinensis (related: sweet orange),cv. Valencia,,,leaf,BLUF domain-containing protein,,,,increased virulence (hypervirulence),,,,,larger canker lesion,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37209300,PubMed,10.1007/s43630-023-00420-6,Photochem Photobiol Sci. 2023 May 20. doi: 10.1007/s43630-023-00420-6. Online ahead of print,orellano@ibr-conicet.gov.ar,The mutant strain rendered a greater amount of cankers on the inoculated area compared to the wild type and complemented strain.,A Carrau 2023,2023,1 gene,Carrau-2023-A novel BLUF photoreceptor modulat,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21969,PHI:124121,UniProt,P0A3X1,GenBank,CAA41091,,,W22703,ymoA,,,,,,,630,Yersinia enterocolitica,913028,W22703,yersiniosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,modulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37184385,PubMed,10.1128/aem.00036-23,Appl Environ Microbiol. 2023 May 15:e0003623. doi: 10.1128/aem.00036-23. Online ahead of print,thilom.fuchs@fli.de.,"Strain W22703 ΔymoA exhibited a strongly enhanced toxicity (P = 0.0026) toward the larvae compared to parental strain W22703, as 69% versus 42% of the larvae died.",P A Sänger 2023,2023,8 genes,S?nger-2023-Regulation and Functionality of a,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21970,PHI:124122,UniProt,Q9S3W0,GenBank,AAD51968,,,JB580v,RovA,,,,,,,630,Yersinia enterocolitica,913028,W22703,yersiniosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,regulatory factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37184385,PubMed,10.1128/aem.00036-23,Appl Environ Microbiol. 2023 May 15:e0003623. doi: 10.1128/aem.00036-23. Online ahead of print,thilom.fuchs@fli.de.,mutant showed no significant attenuation relative to W22703.,P A Sänger 2023,2023,8 genes,S?nger-2023-Regulation and Functionality of a,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21971,PHI:124123,UniProt,F4N4J3,GenBank,CBX73001,,,,tldD,,,,,,,630,Yersinia enterocolitica,913028,W22703,yersiniosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,regulatory factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37184385,PubMed,10.1128/aem.00036-23,Appl Environ Microbiol. 2023 May 15:e0003623. doi: 10.1128/aem.00036-23. Online ahead of print,thilom.fuchs@fli.de.,mutant showed no significant attenuation relative to W22703.,P A Sänger 2023,2023,8 genes,S?nger-2023-Regulation and Functionality of a,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21972,PHI:124124,UniProt,F4N4S6,GenBank,CBX73084,,,,kdpD,,,,,,,630,Yersinia enterocolitica,913028,W22703,yersiniosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,regulatory factor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37184385,PubMed,10.1128/aem.00036-23,Appl Environ Microbiol. 2023 May 15:e0003623. doi: 10.1128/aem.00036-23. Online ahead of print,thilom.fuchs@fli.de.,Mutant showed no significant attenuation relative to W22703.,P A Sänger 2023,2023,8 genes,S?nger-2023-Regulation and Functionality of a,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21973,PHI:124125,UniProt,F4N6Y1,GenBank,CBX73839,,,,luxS,,,,,,,630,Yersinia enterocolitica,913028,W22703,yersiniosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,regulatory factor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37184385,PubMed,10.1128/aem.00036-23,Appl Environ Microbiol. 2023 May 15:e0003623. doi: 10.1128/aem.00036-23. Online ahead of print,thilom.fuchs@fli.de.,Mutant showed significantly high survival rate compared to W22703.,P A Sänger 2023,2023,8 genes,S?nger-2023-Regulation and Functionality of a,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21974,PHI:124126,UniProt,F4N7S0,GenBank,CBX74128,,,,yenI,,,,,,,630,Yersinia enterocolitica,913028,W22703,yersiniosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,regulatory factor,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37184385,PubMed,10.1128/aem.00036-23,Appl Environ Microbiol. 2023 May 15:e0003623. doi: 10.1128/aem.00036-23. Online ahead of print,thilom.fuchs@fli.de.,Mutant showed significantly full survival rate compared to W22703.,P A Sänger 2023,2023,8 genes,S?nger-2023-Regulation and Functionality of a,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21975,PHI:124127,UniProt,Q2WCV0,GenBank,CAI77377,,,W22703,holY,,,,,,,630,Yersinia enterocolitica,913028,W22703,yersiniosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,holin-endolysin system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37184385,PubMed,10.1128/aem.00036-23,Appl Environ Microbiol. 2023 May 15:e0003623. doi: 10.1128/aem.00036-23. Online ahead of print,thilom.fuchs@fli.de.,Deletion of the holY-elyY cassette results in a loss of nematocidal activity of strain W22703.,P A Sänger 2023,2023,8 genes,S?nger-2023-Regulation and Functionality of a,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21976,PHI:124128,UniProt,Q2WCU9,GenBank,CAI77378,,,W22703,elyY,,,,,,,630,Yersinia enterocolitica,913028,W22703,yersiniosis,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,holin-endolysin system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37184385,PubMed,10.1128/aem.00036-23,Appl Environ Microbiol. 2023 May 15:e0003623. doi: 10.1128/aem.00036-23. Online ahead of print,thilom.fuchs@fli.de.,Deletion of the holY-elyY cassette results in a loss of nematocidal activity of strain W22703.,P A Sänger 2023,2023,8 genes,S?nger-2023-Regulation and Functionality of a,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21977,PHI:124129,UniProt,Q87DF4,GenBank,AAO28600,,,Temecula1,XadA1 (PD0731),,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),,,,leaf,autotransporter adhesins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35704683,PubMed,10.1094/MPMI-05-22-0108-R,Mol Plant Microbe Interact. 2022 Sep;35(9):857-866. doi: 10.1094/MPMI-05-22-0108-R. Epub 2022 Sep 14,almsilva@iq.usp.br,XadA1 deletion mutant conferred lower disease severity than the wild-type strain.,O R Feitosa-Junior 2022,2022,3 genes,Feitosa-Junior-2022-The XadA trimeric autotran,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21978,PHI:124130,UniProt,Q87DE1,GenBank,AAO28613,,,Temecula1,XadA2 (PD0744),,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),,,,leaf,autotransporter adhesins,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35704683,PubMed,10.1094/MPMI-05-22-0108-R,Mol Plant Microbe Interact. 2022 Sep;35(9):857-866. doi: 10.1094/MPMI-05-22-0108-R. Epub 2022 Sep 14,almsilva@iq.usp.br,XadA2 deletion mutant conferred lower disease severity than the wild-type strain.,O R Feitosa-Junior 2022,2022,3 genes,Feitosa-Junior-2022-The XadA trimeric autotran,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21979,PHI:124131,UniProt,Q87D62,GenBank,AAO28692,,,Temecula1,xadA3 (PD0824),,,,,,,2371,Xylella fastidiosa,183190,Temecula1,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,29760,Vitis vinifera (related: wine grape),,,,leaf,autotransporter adhesins,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,35704683,PubMed,10.1094/MPMI-05-22-0108-R,Mol Plant Microbe Interact. 2022 Sep;35(9):857-866. doi: 10.1094/MPMI-05-22-0108-R. Epub 2022 Sep 14,almsilva@iq.usp.br,XadA3 mutant was hypervirulent in grapevines.,O R Feitosa-Junior 2022,2022,3 genes,Feitosa-Junior-2022-The XadA trimeric autotran,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21980,PHI:124132,UniProt,A0A384K1I0,GenBank,ATZ56387,,,B05.10,Bcb1 (BCIN_13g02260),chromosome BCIN13,,,,,,40559,Botrytis cinerea,,ACCC37712,grey mold,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit; leaf,acyl-coenzyme A synthetase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,37160639,PubMed,10.1007/s00203-023-03540-w,Arch Microbiol. 2023 Apr 25;205(5):206. doi: 10.1007/s00203-023-03540-w,liangzhihuai2019@163.com,Deletion of Bcb1 caused a reduction in pathogenicity.,J Xiao 2023,2023,1 gene,"Xiao-2023-BCB1, a member of the acyl-coenzyme",BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21981,PHI:124133,UniProt,A0A829CTM5,GenBank,EMY03532,,,2002000626,flhG,,,,,,,173,Leptospira interrogans,,LEPBIa0945,leptospirosis,rodents,10036,Mesocricetus auratus (related: golden hamster),,,,,negative regulator,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34657338,PubMed,10.1111/mmi.14831,Mol Microbiol. 2021 Nov;116(5):1392-1406. doi: 10.1111/mmi.14831. Epub 2021 Oct 30,mpicard@pasteur.fr,L. interrogans flhG− mutant was attenuated for virulence in the hamster model.,L Fule 2021,2021,1 gene,Fule-2021-Role of the major determinant of pol,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21982,PHI:124134,UniProt,A0A8I3AJD1,,,,,,PLA2 (VL1_T00014035),,,,,,,100787,Verticillium longisporum,,VL1,wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,seedling,phospholipase A2,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37171182,PubMed,10.1111/mpp.13352,Mol Plant Pathol. 2023 May 12. doi: 10.1111/mpp.13352. Online ahead of print,georgios.tzelepis@slu.se,Plants infected with the VlsPLA 2+WT strain showed more severe symptoms and smaller rosettes compared to plants infected with the WT and VlsPLA 2+ΔCD strains.,V Rafiei 2023,2023,1 gene,Rafiei-2023-Verticillium longisporum phospholi,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21983,PHI:124136,UniProt,A4QVZ8,GenBank,EHA52211,,,70-15,Nte1,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Golden Promise,,,leaf,effector protein,,,secretion pathway,effector (plant avirulence determinant),,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37306516,PubMed,10.1111/mpp.13356,Mol Plant Pathol. 2023 Jun 12. doi: 10.1111/mpp.13356. Online ahead of print,zonghuaw@163.com,Deletion of the MoNTE1 gene caused a significant reduction of fungal growth and conidiogenesis and attenuated the pathogenicity.,X Chen 2023,2023,1 gene,Chen-2023-A nonclassically secreted effector o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21984,PHI:124136,UniProt,A4QVZ8,GenBank,EHA52211,,,70-15,Nte1,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector protein,,,secretion pathway,effector (plant avirulence determinant),,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37306516,PubMed,10.1111/mpp.13356,Mol Plant Pathol. 2023 Jun 12. doi: 10.1111/mpp.13356. Online ahead of print,zonghuaw@163.com,Deletion of the MoNTE1 gene caused a significant reduction of fungal growth and conidiogenesis and attenuated the pathogenicity.,X Chen 2023,2023,1 gene,Chen-2023-A nonclassically secreted effector o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21985,PHI:124136,UniProt,A4QVZ8,GenBank,EHA52211,,,70-15,Nte1,chromosome 3,Nte1Δnls,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,effector protein,,,secretion pathway,effector (plant avirulence determinant),,,yes,,wild type,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37306516,PubMed,10.1111/mpp.13356,Mol Plant Pathol. 2023 Jun 12. doi: 10.1111/mpp.13356. Online ahead of print,zonghuaw@163.com,MoNte1Δnls developed necrotic lesions on the rice epidermal tissues as severe as the WT.,X Chen 2023,2023,1 gene,Chen-2023-A nonclassically secreted effector o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21986,PHI:124137,UniProt,G1X7H0,GenBank,EGX50801,,,ATCC 24927,Set1 (EGX50801),,,,,,,2813651,Orbilia oligospora,,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histone H3K4 methyltransferase,,,aoSET1 regulatory pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,37233873,PubMed,10.1007/s11427-022-2300-2,Sci China Life Sci. 2023 May 23. doi: 10.1007/s11427-022-2300-2. Online ahead of print,kqzhang1@ynu.edu.cn,"Conidia of ΔAoSet1 was significantly lower than that of the WT strain, and the growth rate and pathogenicity were also compromised.",Q Miao 2023,2023,5 genes,Miao-2023-Nematode-induced trap formation regu,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21987,PHI:124137,UniProt,G1X7H0,GenBank,EGX50801,,,ATCC 24927,Set1 (EGX50801),,lysine residue at position four of the H3 protein is replaced with alanine,,,,,2813651,Orbilia oligospora,,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histone H3K4 methyltransferase,,,aoSET1 regulatory pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,37233873,PubMed,10.1007/s11427-022-2300-2,Sci China Life Sci. 2023 May 23. doi: 10.1007/s11427-022-2300-2. Online ahead of print,kqzhang1@ynu.edu.cn,C. elegans died significantly slower than the WT strain indicating that fungal virulence was significantly reduced in AoH3K4A strain.,Q Miao 2023,2023,5 genes,Miao-2023-Nematode-induced trap formation regu,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21988,PHI:124138,UniProt,G1XRD0,GenBank,EGX44401,,,ATCC 24927,Zip129 (EGX44401),,,,,,,2813651,Orbilia oligospora,,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,leucine zipper (bZip) transcription factors,,,aobZip129 regulatory pathway,reduced virulence,,,,,,reduced,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233873,PubMed,10.1007/s11427-022-2300-2,Sci China Life Sci. 2023 May 23. doi: 10.1007/s11427-022-2300-2. Online ahead of print,kqzhang1@ynu.edu.cn,The deletion Zip129 reduce the fungal virulence of A. oligospra.,Q Miao 2023,2023,5 genes,Miao-2023-Nematode-induced trap formation regu,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21989,PHI:124139,UniProt,G1XDG5,GenBank,EGX48711,,,ATCC 24927,Zip350 (EGX48711),,,,,,,2813651,Orbilia oligospora,,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,histone H3K4 methyltransferase,,,aobZip129- regulatory pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,37233873,PubMed,10.1007/s11427-022-2300-2,Sci China Life Sci. 2023 May 23. doi: 10.1007/s11427-022-2300-2. Online ahead of print,kqzhang1@ynu.edu.cn,The deletion Zip350 reduce the fungal virulence of A. oligospra.,Q Miao 2023,2023,5 genes,Miao-2023-Nematode-induced trap formation regu,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21990,PHI:124140,UniProt,G1XR07,GenBank,EGX44424,,,ATCC 24927,Pabp1 (EGX44424),,,,,,,2813651,Orbilia oligospora,,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,transcription factor binding sites,,,aoPABP1 regulatory pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37233873,PubMed,10.1007/s11427-022-2300-2,Sci China Life Sci. 2023 May 23. doi: 10.1007/s11427-022-2300-2. Online ahead of print,kqzhang1@ynu.edu.cn,Deletion on AoPabp1 mutant showed a significantly higher trap production than the WT strain.,Q Miao 2023,2023,5 genes,Miao-2023-Nematode-induced trap formation regu,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21991,PHI:124141,UniProt,G1X1X8,GenBank,EGX52951,,,ATCC 24927,Cpr1 (EGX52951),,,,,,,2813651,Orbilia oligospora,,ATCC 24927,,nematodes,6239,Caenorhabditis elegans (related: roundworm),,,,,transcription factor binding sites,,,aoCPR1 regulatory pathway,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37233873,PubMed,10.1007/s11427-022-2300-2,Sci China Life Sci. 2023 May 23. doi: 10.1007/s11427-022-2300-2. Online ahead of print,kqzhang1@ynu.edu.cn,Deletion on AoCpr1 mutant showed a significantly higher trap production than the WT strain.,Q Miao 2023,2023,5 genes,Miao-2023-Nematode-induced trap formation regu,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21992,PHI:124142,UniProt,P0CS83,GenBank,AAA34332,,,,Sap2,,Mutation on Sap2-273V to Sap2-273L,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,kidney; lung; liver; brain; spleen,candidapepsin-2,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation,,,NN,37211685,PubMed,10.1002/advs.202206713,Adv Sci (Weinh). 2023 May 21:e2206713. doi: 10.1002/advs.202206713. Online ahead of print,desheng.hu@hust.edu.cn,"Sap2-273L infected mice exhibited higher mortality rates, with 25% of mice dying on day 5 and over 90% dying by day 13 postinfection.",L Lin 2023,2023,1 gene,Lin-2023-Sequence Variation of Candida albican,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21993,PHI:124143,UniProt,P45996,GenBank,AAA24959,,,1128,p5,,NTHi 3655Δp5; NTHi 3655Δp5CTD,,,,,727,Haemophilus influenzae,375177,3655,acute respiratory tract infection; chronic respiratory tract infection,primates,9606,Homo sapiens (related: human),A549 cell line,,,epithelial cell,outer membrane protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37305414,PubMed,10.3389/fcimb.2023.1085908,Front Cell Infect Microbiol. 2023 May 26;13:1085908. doi: 10.3389/fcimb.2023.1085908. eCollection 2023,kristian.riesbeck@med.lu.se,Wild type shows complete survival than the mutants; Δp5CTD mutant survived better (53% of survival) than the NTHi 3655Δp5 which was almost fully killed (1.9% survival).,Y C Su 2023,2023,1 gene,Su-2023-Non-typeable Haemophilus influenzae ma,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21994,PHI:124144,UniProt,Q9KMR3,GenBank,AAF96168,,,N16961,RvvA (VCA0257),chromosome II,,,,,,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvA displayed a significant colonization defect in intestine and increased transcription of biofilm genes and altered biofilm formation.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21995,PHI:124145,UniProt,Q9KMR4,GenBank,AAF96167,,,N16961,RvvB (VCA0256),chromosome II,,,,,,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvB displayed a no significant colonization defect in intestine.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21996,PHI:124146,UniProt,Q9KMR5,GenBank,AAF96166,,,N16961,RvvC (VCA0255),chromosome II,,,,,,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvC displayed a no significant colonization defect in intestine.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21997,PHI:124147,UniProt,Q9KMR6,GenBank,AAF96165,,,N16961,RvvD (VCA0254),chromosome II,,,,,,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvD displayed a no significant colonization defect in intestine.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21998,PHI:124148,UniProt,Q9KMR2,GenBank,AAF96169,,,N16961,RvvE (VCA0258),chromosome II,,,,,,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvE displayed a no significant colonization defect in intestine.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 21999,PHI:124144,UniProt,Q9KMR3,GenBank,AAF96168,,,N16961,RvvA (VCA0257),chromosome II,,,,,PHI:124146,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvAC displayed a significant colonization defect in intestine.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22000,PHI:124146,UniProt,Q9KMR5,GenBank,AAF96166,,,N16961,RvvC (VCA0255),chromosome II,,,,,PHI:124144,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvAC displayed a significant colonization defect in intestine.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22001,PHI:124144,UniProt,Q9KMR3,GenBank,AAF96168,,,N16961,RvvA (VCA0257),chromosome II,,,,,PHI:124147,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvAD displayed a significant colonization defect in intestine.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22002,PHI:124147,UniProt,Q9KMR6,GenBank,AAF96165,,,N16961,RvvD (VCA0254),chromosome II,,,,,PHI:124144,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvAD displayed a significant colonization defect in intestine.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22003,PHI:124144,UniProt,Q9KMR3,GenBank,AAF96168,,,N16961,RvvA (VCA0257),chromosome II,,,,,PHI:124148,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvAE displayed a significant colonization defect in intestine.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22004,PHI:124148,UniProt,Q9KMR2,GenBank,AAF96169,,,N16961,RvvE (VCA0258),chromosome II,,,,,PHI:124144,666,Vibrio cholerae,,A1552,cholera,rodents,10090,Mus musculus (related: house mouse),CD-1,,,Intestine,two-component regulatory system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37216386,PubMed,10.1371/journal.ppat.1011415,PLoS Pathog. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415. eCollection 2023 May,fyildiz@ucsc.edu,ΔrvvAE displayed a significant colonization defect in intestine.,G Kitts 2023,2023,5 genes,Kitts-2023-The Rvv two-component regulatory sy,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22005,PHI:124149,UniProt,A0A0H3JYW1,GenBank,BAB96184,,,MW2,narG,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,nitrate reductase,,,,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37199609,PubMed,10.1128/spectrum.03596-22,Microbiol Spectr. 2023 Jun 15;11(3):e0359622. doi: 10.1128/spectrum.03596-22. Epub 2023 May 18,sunb@ustc.edu.cn,Bacterial colonization in the skin abscesses was considerably reduced in ΔnarG-infected mice compared to that in USA300 LAC-infected mice.,Y Li 2023,2023,2 genes,Li-2023-Nitrate Reductase NarGHJI Modulates Vi,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22006,PHI:124149,UniProt,A0A0H3JYW1,GenBank,BAB96184,,,MW2,narG,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,nitrate reductase,,,,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37199609,PubMed,10.1128/spectrum.03596-22,Microbiol Spectr. 2023 Jun 15;11(3):e0359622. doi: 10.1128/spectrum.03596-22. Epub 2023 May 18,sunb@ustc.edu.cn,narGHJI disruption resulted in decreased virulence using G. mellonella larvae as the target host.,Y Li 2023,2023,2 genes,Li-2023-Nitrate Reductase NarGHJI Modulates Vi,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22007,PHI:124149,UniProt,A0A0H3JYW1,GenBank,BAB96184,,,MW2,narG,,,,,,PHI:124150,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,nitrate reductase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37199609,PubMed,10.1128/spectrum.03596-22,Microbiol Spectr. 2023 Jun 15;11(3):e0359622. doi: 10.1128/spectrum.03596-22. Epub 2023 May 18,sunb@ustc.edu.cn,No significant changes were observed in the virulence of the Δ narG mutant and the narG agr double mutant using G. mellonella larvae as the target host.,Y Li 2023,2023,2 genes,Li-2023-Nitrate Reductase NarGHJI Modulates Vi,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22008,PHI:124150,,no data found,,,,,,agr,,,,,,PHI:124149,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,virulence gene,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37199609,PubMed,10.1128/spectrum.03596-22,Microbiol Spectr. 2023 Jun 15;11(3):e0359622. doi: 10.1128/spectrum.03596-22. Epub 2023 May 18,sunb@ustc.edu.cn,No significant changes were observed in the virulence of the Δ narG mutant and the narG agr double mutant using G. mellonella larvae as the target host.,Y Li 2023,2023,2 genes,Li-2023-Nitrate Reductase NarGHJI Modulates Vi,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22009,PHI:124150,,no data found,,,,,,agr,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,virulence gene,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37199609,PubMed,10.1128/spectrum.03596-22,Microbiol Spectr. 2023 Jun 15;11(3):e0359622. doi: 10.1128/spectrum.03596-22. Epub 2023 May 18,sunb@ustc.edu.cn,Virulence of the agr mutant to G. mellonella could match that of the ΔnarG mutant.,Y Li 2023,2023,2 genes,Li-2023-Nitrate Reductase NarGHJI Modulates Vi,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22010,PHI:124150,,no data found,,,,,,agr,,,,,,,1280,Staphylococcus aureus,367830,USA300 LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,skin,virulence gene,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37199609,PubMed,10.1128/spectrum.03596-22,Microbiol Spectr. 2023 Jun 15;11(3):e0359622. doi: 10.1128/spectrum.03596-22. Epub 2023 May 18,sunb@ustc.edu.cn,"The Δagr mutant caused almost no visible mouse subcutaneous abscess, leukocyte infiltration, and destruction of the skin structure.",Y Li 2023,2023,2 genes,Li-2023-Nitrate Reductase NarGHJI Modulates Vi,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22011,PHI:124151,UniProt,Q2G1N7,GenBank,ABD29254,,,NCTC 8325,SarS,,,,,,,1280,Staphylococcus aureus,,AH-LAC,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,,transcription factor,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36939325,PubMed,10.1128/iai.00532-22,Infect Immun. 2023 Apr 18;91(4):e0053222. doi: 10.1128/iai.00532-22. Epub 2023 Mar 20,victor.torres@nyulangone.org,Significantly more mice infected with the ΔsarS strain succumbed to the infection than the mice infected with the wildtype strain.,E E Anderson 2023,2023,1 gene,Anderson-2023-SarS Is a Repressor of Staphyloc,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22012,PHI:124152,,no data found,,,,,,dppA (=DS0823_v1_2392),,,,,,,1089444,Dickeya solani,1240086,RNS 08.23.3.1A,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,stem; tuber; root,oligopeptide transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37223796,PubMed,10.3389/fpls.2023.1154110,Front Plant Sci. 2023 May 8;14:1154110. doi: 10.3389/fpls.2023.1154110. eCollection 2023,denis.faure@i2bc.paris-saclay.fr,The mutants caused similar lesions to those of the wild-type strain.,K Robic 2023,2023,4 genes,Robic-2023-Dissimilar gene repertoires of Dick,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22013,PHI:124153,UniProt,A0A2K8VWF9,,,,,,pstA (=DS0823_v1_2527),,,,,,,1089444,Dickeya solani,1240086,RNS 08.23.3.1A,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,stem; tuber; root,a phosphate transporter,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37223796,PubMed,10.3389/fpls.2023.1154110,Front Plant Sci. 2023 May 8;14:1154110. doi: 10.3389/fpls.2023.1154110. eCollection 2023,denis.faure@i2bc.paris-saclay.fr,The mutants caused similar lesions to those of the wild-type strain.,K Robic 2023,2023,4 genes,Robic-2023-Dissimilar gene repertoires of Dick,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22014,PHI:124154,UniProt,A0A2K8VZT6,,,,,,bcsA (=DS0823_v1_2374),,,,,,,1089444,Dickeya solani,1240086,RNS 08.23.3.1A,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,stem; tuber; root,cellulose synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37223796,PubMed,10.3389/fpls.2023.1154110,Front Plant Sci. 2023 May 8;14:1154110. doi: 10.3389/fpls.2023.1154110. eCollection 2023,denis.faure@i2bc.paris-saclay.fr,The mutants caused similar lesions to those of the wild-type strain.,K Robic 2023,2023,4 genes,Robic-2023-Dissimilar gene repertoires of Dick,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22015,PHI:124155,,no data found,,,,,,apeH (=DS0823_v1_2513),,,,,,,1089444,Dickeya solani,1240086,RNS 08.23.3.1A,soft rot; blackleg disease,eudicots,4113,Solanum tuberosum (related: potato),,,,stem; tuber; root,aryl-polyene synthase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37223796,PubMed,10.3389/fpls.2023.1154110,Front Plant Sci. 2023 May 8;14:1154110. doi: 10.3389/fpls.2023.1154110. eCollection 2023,denis.faure@i2bc.paris-saclay.fr,The mutants caused similar lesions to those of the wild-type strain.,K Robic 2023,2023,4 genes,Robic-2023-Dissimilar gene repertoires of Dick,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22016,PHI:124156,UniProt,I1RSN3,GenBank,FGSG_07159,,,,Ham2,,,,Ppg1; Ham3,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,STRIPAK complex,,,TOR signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278525,PubMed,10.1111/mpp.13359,Mol Plant Pathol. 2023 Jun 6. doi: 10.1111/mpp.13359. Online ahead of print,chenyun0927@zju.edu.cn,"Deletion mutations of individual components of the STRIPAK complex cause a significant reduction in fungal vegetative growth and sexual development, and dramatically attenuae virulence.",A Chen 2023,2023,5 genes,Chen-2023-The STRIPAK complex orchestrates cel,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22017,PHI:124157,UniProt,I1RDG9,GenBank,FGSG_01665,,,,Ham3,,,,Ppg1; Ham2; Mob3,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,STRIPAK complex,,,TOR signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278525,PubMed,10.1111/mpp.13359,Mol Plant Pathol. 2023 Jun 6. doi: 10.1111/mpp.13359. Online ahead of print,chenyun0927@zju.edu.cn,"Deletion mutations of individual components of the STRIPAK complex cause a significant reduction in fungal vegetative growth and sexual development, and dramatically attenuae virulence.",A Chen 2023,2023,5 genes,Chen-2023-The STRIPAK complex orchestrates cel,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22018,PHI:124158,UniProt,I1RXZ4,GenBank,FGSG_09221,,,,Ham4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,STRIPAK complex,,,TOR signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278525,PubMed,10.1111/mpp.13359,Mol Plant Pathol. 2023 Jun 6. doi: 10.1111/mpp.13359. Online ahead of print,chenyun0927@zju.edu.cn,"Deletion mutations of individual components of the STRIPAK complex cause a significant reduction in fungal vegetative growth and sexual development, and dramatically attenuae virulence.",A Chen 2023,2023,5 genes,Chen-2023-The STRIPAK complex orchestrates cel,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22019,PHI:124159,UniProt,I1RMT4,GenBank,FGSG_05281,,,,Ppg1,,,,Ham3; Ham2; Mob3,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,STRIPAK complex,,,TOR signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278525,PubMed,10.1111/mpp.13359,Mol Plant Pathol. 2023 Jun 6. doi: 10.1111/mpp.13359. Online ahead of print,chenyun0927@zju.edu.cn,"Deletion mutations of individual components of the STRIPAK complex cause a significant reduction in fungal vegetative growth and sexual development, and dramatically attenuae virulence.",A Chen 2023,2023,5 genes,Chen-2023-The STRIPAK complex orchestrates cel,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22020,PHI:124160,UniProt,I1RMB3,GenBank,FGSG_05101,,,,Mob3,,,,Ham3; Ppg1,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spikelet,STRIPAK complex,,,TOR signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278525,PubMed,10.1111/mpp.13359,Mol Plant Pathol. 2023 Jun 6. doi: 10.1111/mpp.13359. Online ahead of print,chenyun0927@zju.edu.cn,"Deletion mutations of individual components of the STRIPAK complex cause a significant reduction in fungal vegetative growth and sexual development, and dramatically attenuae virulence.",A Chen 2023,2023,5 genes,Chen-2023-The STRIPAK complex orchestrates cel,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22021,PHI:124156,UniProt,I1RSN3,GenBank,FGSG_07159,,,,Ham2,,,,Ppg1; Ham3,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,STRIPAK complex,,,TOR signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278525,PubMed,10.1111/mpp.13359,Mol Plant Pathol. 2023 Jun 6. doi: 10.1111/mpp.13359. Online ahead of print,chenyun0927@zju.edu.cn,"Deletion mutations of individual components of the STRIPAK complex cause a significant reduction in fungal vegetative growth and sexual development, and dramatically attenuae virulence.",A Chen 2023,2023,5 genes,Chen-2023-The STRIPAK complex orchestrates cel,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22022,PHI:124157,UniProt,I1RDG9,GenBank,FGSG_01665,,,,Ham3,,,,Ppg1; Ham2; Mob3,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,STRIPAK complex,,,TOR signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278525,PubMed,10.1111/mpp.13359,Mol Plant Pathol. 2023 Jun 6. doi: 10.1111/mpp.13359. Online ahead of print,chenyun0927@zju.edu.cn,"Deletion mutations of individual components of the STRIPAK complex cause a significant reduction in fungal vegetative growth and sexual development, and dramatically attenuae virulence.",A Chen 2023,2023,5 genes,Chen-2023-The STRIPAK complex orchestrates cel,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22023,PHI:124158,UniProt,I1RXZ4,GenBank,FGSG_09221,,,,Ham4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,corn silk,STRIPAK complex,,,TOR signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278525,PubMed,10.1111/mpp.13359,Mol Plant Pathol. 2023 Jun 6. doi: 10.1111/mpp.13359. Online ahead of print,chenyun0927@zju.edu.cn,"Deletion mutations of individual components of the STRIPAK complex cause a significant reduction in fungal vegetative growth and sexual development, and dramatically attenuae virulence.",A Chen 2023,2023,5 genes,Chen-2023-The STRIPAK complex orchestrates cel,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22024,PHI:124159,UniProt,I1RMT4,GenBank,FGSG_05281,,,,Ppg1,,,,Ham3; Ham2; Mob3,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,STRIPAK complex,,,TOR signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278525,PubMed,10.1111/mpp.13359,Mol Plant Pathol. 2023 Jun 6. doi: 10.1111/mpp.13359. Online ahead of print,chenyun0927@zju.edu.cn,"Deletion mutations of individual components of the STRIPAK complex cause a significant reduction in fungal vegetative growth and sexual development, and dramatically attenuae virulence.",A Chen 2023,2023,5 genes,Chen-2023-The STRIPAK complex orchestrates cel,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22025,PHI:124160,UniProt,I1RMB3,GenBank,FGSG_05101,,,,Mob3,,,,Ham3; Ppg1,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike,STRIPAK complex,,,TOR signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37278525,PubMed,10.1111/mpp.13359,Mol Plant Pathol. 2023 Jun 6. doi: 10.1111/mpp.13359. Online ahead of print,chenyun0927@zju.edu.cn,"Deletion mutations of individual components of the STRIPAK complex cause a significant reduction in fungal vegetative growth and sexual development, and dramatically attenuae virulence.",A Chen 2023,2023,5 genes,Chen-2023-The STRIPAK complex orchestrates cel,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22026,PHI:124161,UniProt,A0A7X0PXM9,GenBank,MBB6581078,,,CCRMRsB7,aroQ1,,,,,,,305,Ralstonia solanacearum,,RK5050,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,petiole,3-dehydroquinase,,,shikimate pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37180250,PubMed,10.3389/fmicb.2023.1186688,Front Microbiol. 2023 Apr 26;14:1186688. doi: 10.3389/fmicb.2023.1186688. eCollection 2023,x_wangyan@163.com,Deletion of aroQ1 did not alter the growth of R. solanacearum or pathogenicity on host plants.,Q Zhang 2023,2023,2 genes,Zhang-2023-Functional characterization of two,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22027,PHI:124161,UniProt,A0A7X0PXM9,GenBank,MBB6581078,,,CCRMRsB7,aroQ1,,,,,,,305,Ralstonia solanacearum,,RK5050,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),Bright Yellow,,,leaf,3-dehydroquinase,,,shikimate pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37180250,PubMed,10.3389/fmicb.2023.1186688,Front Microbiol. 2023 Apr 26;14:1186688. doi: 10.3389/fmicb.2023.1186688. eCollection 2023,x_wangyan@163.com,Deletion of aroQ1 did not alter the growth of R. solanacearum or pathogenicity on host plants.,Q Zhang 2023,2023,2 genes,Zhang-2023-Functional characterization of two,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22028,PHI:124162,UniProt,A0A7U7JDS0,GenBank,CEJ16844,,,IPO1609,aroQ2,,,,,,,305,Ralstonia solanacearum,,RK5050,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),Bright Yellow,,,leaf,3-dehydroquinase,,,shikimate pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37180250,PubMed,10.3389/fmicb.2023.1186688,Front Microbiol. 2023 Apr 26;14:1186688. doi: 10.3389/fmicb.2023.1186688. eCollection 2023,x_wangyan@163.com,Deletion of aroQ2 did not alter the growth of R. solanacearum or pathogenicity on host plants.,Q Zhang 2023,2023,2 genes,Zhang-2023-Functional characterization of two,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22029,PHI:124162,UniProt,A0A7U7JDS0,GenBank,CEJ16844,,,IPO1609,aroQ2,,,,,,,305,Ralstonia solanacearum,,RK5050,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,petiole,3-dehydroquinase,,,shikimate pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37180250,PubMed,10.3389/fmicb.2023.1186688,Front Microbiol. 2023 Apr 26;14:1186688. doi: 10.3389/fmicb.2023.1186688. eCollection 2023,x_wangyan@163.com,Deletion of aroQ2 did not alter the growth of R. solanacearum or pathogenicity on host plants.,Q Zhang 2023,2023,2 genes,Zhang-2023-Functional characterization of two,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22030,PHI:124161,UniProt,A0A7X0PXM9,GenBank,MBB6581078,,,CCRMRsB7,aroQ1,,,,,,PHI:124162,305,Ralstonia solanacearum,,RK5050,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,petiole,3-dehydroquinase,,,shikimate pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37180250,PubMed,10.3389/fmicb.2023.1186688,Front Microbiol. 2023 Apr 26;14:1186688. doi: 10.3389/fmicb.2023.1186688. eCollection 2023,x_wangyan@163.com,aroQ1/2 double mutant failed to cause any wilting symptoms on two plants till 24 dpi,Q Zhang 2023,2023,2 genes,Zhang-2023-Functional characterization of two,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22031,PHI:124162,UniProt,A0A7U7JDS0,GenBank,CEJ16844,,,IPO1609,aroQ2,,,,,,PHI:124161,305,Ralstonia solanacearum,,RK5050,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,petiole,3-dehydroquinase,,,shikimate pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37180250,PubMed,10.3389/fmicb.2023.1186688,Front Microbiol. 2023 Apr 26;14:1186688. doi: 10.3389/fmicb.2023.1186688. eCollection 2023,x_wangyan@163.com,aroQ1/2 double mutant failed to cause any wilting symptoms on two plants till 24 dpi,Q Zhang 2023,2023,2 genes,Zhang-2023-Functional characterization of two,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22032,PHI:124161,UniProt,A0A7X0PXM9,GenBank,MBB6581078,,,CCRMRsB7,aroQ1,,,,,,PHI:124162,305,Ralstonia solanacearum,,RK5050,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),Bright Yellow,,,leaf,3-dehydroquinase,,,shikimate pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37180250,PubMed,10.3389/fmicb.2023.1186688,Front Microbiol. 2023 Apr 26;14:1186688. doi: 10.3389/fmicb.2023.1186688. eCollection 2023,x_wangyan@163.com,aroQ1/2 double mutant failed to cause any wilting symptoms on two plants till 24 dpi,Q Zhang 2023,2023,2 genes,Zhang-2023-Functional characterization of two,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22033,PHI:124162,UniProt,A0A7U7JDS0,GenBank,CEJ16844,,,IPO1609,aroQ2,,,,,,PHI:124161,305,Ralstonia solanacearum,,RK5050,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),Bright Yellow,,,leaf,3-dehydroquinase,,,shikimate pathway,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37180250,PubMed,10.3389/fmicb.2023.1186688,Front Microbiol. 2023 Apr 26;14:1186688. doi: 10.3389/fmicb.2023.1186688. eCollection 2023,x_wangyan@163.com,aroQ1/2 double mutant failed to cause any wilting symptoms on two plants till 24 dpi,Q Zhang 2023,2023,2 genes,Zhang-2023-Functional characterization of two,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22034,PHI:124163,UniProt,P0A9Q1,GenBank,AAA97297,,,K-12,ArcA,,,,,,PHI:124164,562,Escherichia coli,,UTI89,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney; vagina; urine,two-component system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37292752,PubMed,10.1101/2023.05.23.541942,bioRxiv. 2023 May 23:2023.05.23.541942. doi: 10.1101/2023.05.23.541942. Preprint,maria.hadjifrangiskou@vumc.org,"Mice infected with ΔarcAΔarcB, had a shorter time to resolution event, compared to wild-type UTI89.",J R Brannon 2023,2023,7 genes,Brannon-2023-Mapping Niche-specific Two-Compon,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22035,PHI:124164,UniProt,P0AEC3,GenBank,CAA37397,,,K-12,ArcB,,,,,,PHI:124163,562,Escherichia coli,,UTI89,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney; vagina; urine,two-component system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37292752,PubMed,10.1101/2023.05.23.541942,bioRxiv. 2023 May 23:2023.05.23.541942. doi: 10.1101/2023.05.23.541942. Preprint,maria.hadjifrangiskou@vumc.org,"Mice infected with ΔarcAΔarcB, had a shorter time to resolution event, compared to wild-type UTI89.",J R Brannon 2023,2023,7 genes,Brannon-2023-Mapping Niche-specific Two-Compon,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22036,PHI:124165,UniProt,P0AEV1,GenBank,CAA46802,,,K-12,rssB,,,,,,,562,Escherichia coli,,UTI89,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney; vagina; urine,regulator protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37292752,PubMed,10.1101/2023.05.23.541942,bioRxiv. 2023 May 23:2023.05.23.541942. doi: 10.1101/2023.05.23.541942. Preprint,maria.hadjifrangiskou@vumc.org,"Mice infected with rssB, had a shorter time to resolution event, compared to wild-type UTI89.",J R Brannon 2023,2023,7 genes,Brannon-2023-Mapping Niche-specific Two-Compon,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22037,PHI:124166,UniProt,P0AFA2,GenBank,CAA31741,,,K-12,narX,,,,,,PHI:124167,562,Escherichia coli,,UTI89,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney; vagina; urine,two-component system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37292752,PubMed,10.1101/2023.05.23.541942,bioRxiv. 2023 May 23:2023.05.23.541942. doi: 10.1101/2023.05.23.541942. Preprint,maria.hadjifrangiskou@vumc.org,"Mice infected with narXL, had a shorter time to resolution event, compared to wild-type UTI89.",J R Brannon 2023,2023,7 genes,Brannon-2023-Mapping Niche-specific Two-Compon,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22038,PHI:124167,UniProt,P0AF28,GenBank,CAA31742,,,K-12,narL,,,,,,PHI:124166,562,Escherichia coli,,UTI89,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney; vagina; urine,two-component system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37292752,PubMed,10.1101/2023.05.23.541942,bioRxiv. 2023 May 23:2023.05.23.541942. doi: 10.1101/2023.05.23.541942. Preprint,maria.hadjifrangiskou@vumc.org,"Mice infected with narXL, had a shorter time to resolution event, compared to wild-type UTI89.",J R Brannon 2023,2023,7 genes,Brannon-2023-Mapping Niche-specific Two-Compon,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22039,PHI:124168,UniProt,P23836,GenBank,BAA14390,,,K-12,phoP,,,,,,PHI:124169,562,Escherichia coli,,UTI89,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney; vagina; urine,two-component system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37292752,PubMed,10.1101/2023.05.23.541942,bioRxiv. 2023 May 23:2023.05.23.541942. doi: 10.1101/2023.05.23.541942. Preprint,maria.hadjifrangiskou@vumc.org,"Mice infected with phoPQ, had a shorter time to resolution event, compared to wild-type UTI89.",J R Brannon 2023,2023,7 genes,Brannon-2023-Mapping Niche-specific Two-Compon,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22040,PHI:124169,UniProt,P23837,GenBank,BAA14391,,,K-12,phoQ,,,,,,PHI:124168,562,Escherichia coli,,UTI89,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,bladder; kidney; vagina; urine,two-component system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37292752,PubMed,10.1101/2023.05.23.541942,bioRxiv. 2023 May 23:2023.05.23.541942. doi: 10.1101/2023.05.23.541942. Preprint,maria.hadjifrangiskou@vumc.org,"Mice infected with phoPQ, had a shorter time to resolution event, compared to wild-type UTI89.",J R Brannon 2023,2023,7 genes,Brannon-2023-Mapping Niche-specific Two-Compon,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22041,PHI:124170,UniProt,J9VPF8,GenBank,AFR95311,,,H99,mrs3 (CNAG_02522),chromosome 6,,,,,PHI:124171,5207,Cryptococcus neoformans,235443,var. grubii strain H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; kidney; liver; spleen; blood,mitochondrial iron transporter,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,32522963,PubMed,10.4014/jmb.2004.04041,J Microbiol Biotechnol. 2020 Aug 28;30(8):1142-1148. doi: 10.4014/jmb.2004.04041,whjung@cau.ac.kr,mrs3/4 mutant is defective in survival and virulence,Y Choi 2020,2020,2 genes,Choi-2020-Involvement of Mrs3_4 in Mitochondri,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22042,PHI:124171,UniProt,J9VPF8,GenBank,AFR95311,,,H99,mrs4 (CNAG_02522),chromosome 6,,,,,PHI:124170,5207,Cryptococcus neoformans,235443,var. grubii strain H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung; brain; kidney; liver; spleen; blood,mitochondrial iron transporter,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,32522963,PubMed,10.4014/jmb.2004.04041,J Microbiol Biotechnol. 2020 Aug 28;30(8):1142-1148. doi: 10.4014/jmb.2004.04041,whjung@cau.ac.kr,mrs3/4 mutant is defective in survival and virulence,Y Choi 2020,2020,2 genes,Choi-2020-Involvement of Mrs3_4 in Mitochondri,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22043,PHI:124172,,no data found,,,,,,Ena1,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,flowering plants,215539,Liriodendron chinense x Liriodendron tulipifera (no common name found),,,,leaf,exitus natru-type adenosine triphosphatase,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233277,PubMed,10.3390/jof9050566,J Fungi (Basel). 2023 May 13;9(5):566. doi: 10.3390/jof9050566,lhuang@njfu.edu.cn,"CgEna1 was involved in conidial germination, appressorium formation, invasive hyphal development, and full virulence.",T C Deng 2023,2023,4 genes,Deng-2023-Distinct Roles of Ena ATP Family Pro,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22044,PHI:124173,UniProt,L2GCA7,,,,,,Ena2,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,flowering plants,215539,Liriodendron chinense x Liriodendron tulipifera (no common name found),,,,leaf,exitus natru-type adenosine triphosphatase,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233277,PubMed,10.3390/jof9050566,J Fungi (Basel). 2023 May 13;9(5):566. doi: 10.3390/jof9050566,lhuang@njfu.edu.cn,"CgEna2 was same as wild type in conidial germination, appressorium formation, invasive hyphal development, and full virulence.",T C Deng 2023,2023,4 genes,Deng-2023-Distinct Roles of Ena ATP Family Pro,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22045,PHI:124174,,no data found,,,,,,Ena3,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,flowering plants,215539,Liriodendron chinense x Liriodendron tulipifera (no common name found),,,,leaf,exitus natru-type adenosine triphosphatase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233277,PubMed,10.3390/jof9050566,J Fungi (Basel). 2023 May 13;9(5):566. doi: 10.3390/jof9050566,lhuang@njfu.edu.cn,"CgEna3 was involved in conidial germination, appressorium formation, invasive hyphal development, and full virulence.",T C Deng 2023,2023,4 genes,Deng-2023-Distinct Roles of Ena ATP Family Pro,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22046,PHI:124175,,no data found,,,,,,Ena4,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,flowering plants,215539,Liriodendron chinense x Liriodendron tulipifera (no common name found),,,,leaf,exitus natru-type adenosine triphosphatase,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233277,PubMed,10.3390/jof9050566,J Fungi (Basel). 2023 May 13;9(5):566. doi: 10.3390/jof9050566,lhuang@njfu.edu.cn,"CgEna4 was same as wild type in conidial germination, appressorium formation, invasive hyphal development, and full virulence.",T C Deng 2023,2023,4 genes,Deng-2023-Distinct Roles of Ena ATP Family Pro,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22047,PHI:124172,,no data found,,,,,,Ena1,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,seed plants,28977,Cunninghamia lanceolata (related: china fir),,,,leaf,exitus natru-type adenosine triphosphatase,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233277,PubMed,10.3390/jof9050566,J Fungi (Basel). 2023 May 13;9(5):566. doi: 10.3390/jof9050566,lhuang@njfu.edu.cn,"CgEna1 was involved in conidial germination, appressorium formation, invasive hyphal development, and full virulence.",T C Deng 2023,2023,4 genes,Deng-2023-Distinct Roles of Ena ATP Family Pro,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22048,PHI:124173,UniProt,L2GCA7,,,,,,Ena2,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,seed plants,28977,Cunninghamia lanceolata (related: china fir),,,,leaf,exitus natru-type adenosine triphosphatase,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233277,PubMed,10.3390/jof9050566,J Fungi (Basel). 2023 May 13;9(5):566. doi: 10.3390/jof9050566,lhuang@njfu.edu.cn,"CgEna2 was same as wild type in conidial germination, appressorium formation, invasive hyphal development, and full virulence.",T C Deng 2023,2023,4 genes,Deng-2023-Distinct Roles of Ena ATP Family Pro,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22049,PHI:124174,,no data found,,,,,,Ena3,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,seed plants,28977,Cunninghamia lanceolata (related: china fir),,,,leaf,exitus natru-type adenosine triphosphatase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233277,PubMed,10.3390/jof9050566,J Fungi (Basel). 2023 May 13;9(5):566. doi: 10.3390/jof9050566,lhuang@njfu.edu.cn,"CgEna3 was involved in conidial germination, appressorium formation, invasive hyphal development, and full virulence.",T C Deng 2023,2023,4 genes,Deng-2023-Distinct Roles of Ena ATP Family Pro,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22050,PHI:124175,,no data found,,,,,,Ena4,,,,,,,474922,Colletotrichum gloeosporioides,,SMCG1#C,fruit rot,seed plants,28977,Cunninghamia lanceolata (related: china fir),,,,leaf,exitus natru-type adenosine triphosphatase,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233277,PubMed,10.3390/jof9050566,J Fungi (Basel). 2023 May 13;9(5):566. doi: 10.3390/jof9050566,lhuang@njfu.edu.cn,"CgEna4 was same as wild type in conidial germination, appressorium formation, invasive hyphal development, and full virulence.",T C Deng 2023,2023,4 genes,Deng-2023-Distinct Roles of Ena ATP Family Pro,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22051,PHI:124176,UniProt,A1TTW9,GenBank,ABM34407,,,AAC00-1,aclR (WP_0117960894.1),,,,,,,80869,Paracidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 6,,,seedling; leaf,luxR-type global regular,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33779205,PubMed,10.1094/MPMI-01-21-0020-R,Mol Plant Microbe Interact. 2021 Aug;34(8):952-961. doi: 10.1094/MPMI-01-21-0020-R. Epub 2021 Sep 7,wtl82@163.com,"The disease index (DI) of the wild-type strain was 48.88, which was significantly higher than that of the DaclR strain (DI = 29.01), and was similar to that of the complementation strain DaclR-c (DI = 42.09).",W Guan 2021,2021,1 gene,Guan-2021-Transcriptomic and functional analys,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22052,PHI:124177,UniProt,F9XMK0,GenBank,EGP83262,,,IPO323,BCK1,chromosome 11,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,fungal signalling pathway,,,CWI pathway,loss of pathogenicity,,,,,no lesion,,,reduced ; defective,,no,,,,,,,gene deletion: full,,,NN,37306534,PubMed,10.1111/mpp.13365,Mol Plant Pathol. 2023 Jun 12. doi: 10.1111/mpp.13365. Online ahead of print,s.bates@exeter.ac.uk,Chlorosis was not observed on mock-inoculated or Δztbck1-infected leaves.,H T Child 2023,2023,2 genes,Child-2023-Comparison of the impact of two key,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22053,PHI:124178,UniProt,F9XEG7,GenBank,EGP86621,,,IPO323,BCK1,chromosome 6,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),cv. Riband,,,leaf,fungal signalling pathway,,,CWI pathway,reduced virulence,,,,,no lesion,,,reduced ; defective,,no,,,,,,,gene deletion: full,,,NN,37306534,PubMed,10.1111/mpp.13365,Mol Plant Pathol. 2023 Jun 12. doi: 10.1111/mpp.13365. Online ahead of print,s.bates@exeter.ac.uk,"Mild chlorosis caused by L2 and C5 was not observed on Δztcyr1-infected leaves at 21 dpi, continuation of infection to 35 dpi led to the appearance of chlorosis on these leaves.",H T Child 2023,2023,2 genes,Child-2023-Comparison of the impact of two key,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22054,PHI:124179,UniProt,Q9ZGA0,GenBank,AAC98783,,,PAO1,ampD,,,,,,PHI:124180; PHI:124181,287,Pseudomonas aeruginosa,208964; 652611,PAO1; PA14,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,N-acetyl-anhydromuramyl-L-alanine amidase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,NN,36214681,PubMed,10.1128/spectrum.02700-22,Microbiol Spectr. 2022 Oct 26;10(5):e0270022. doi: 10.1128/spectrum.02700-22. Epub 2022 Oct 10,carlos.juan@ssib.es,"PAΔDDh2Dh3 displayed dramatic virulence attenuation, evidenced through a spectacular increase in its 50% lethal dose (LD50).",I M Barceló 2022,2022,5 genes,Barcelo-2022-Role of Enzymatic Activity in the,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22055,PHI:124180,UniProt,Q9HT86,GenBank,AAG08870,,,PAO1,ampDh2,,,,,,PHI:124179; PHI:124181,287,Pseudomonas aeruginosa,208964; 652611,PAO1; PA14,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,N-acetyl-anhydromuramyl-L-alanine amidase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,NN,36214681,PubMed,10.1128/spectrum.02700-22,Microbiol Spectr. 2022 Oct 26;10(5):e0270022. doi: 10.1128/spectrum.02700-22. Epub 2022 Oct 10,carlos.juan@ssib.es,"PAΔDDh2Dh3 displayed dramatic virulence attenuation, evidenced through a spectacular increase in its 50% lethal dose (LD50).",I M Barceló 2022,2022,5 genes,Barcelo-2022-Role of Enzymatic Activity in the,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22056,PHI:124181,UniProt,Q9I5D1,GenBank,AAG04196,,,PAO1,ampDh3,,,,,,PHI:124179; PHI:124180,287,Pseudomonas aeruginosa,208964; 652611,PAO1; PA14,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,N-acetyl-anhydromuramyl-L-alanine amidase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,NN,36214681,PubMed,10.1128/spectrum.02700-22,Microbiol Spectr. 2022 Oct 26;10(5):e0270022. doi: 10.1128/spectrum.02700-22. Epub 2022 Oct 10,carlos.juan@ssib.es,"PAΔDDh2Dh3 displayed dramatic virulence attenuation, evidenced through a spectacular increase in its 50% lethal dose (LD50).",I M Barceló 2022,2022,5 genes,Barcelo-2022-Role of Enzymatic Activity in the,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22057,PHI:124182,UniProt,P24735,GenBank,CAA38522,,,PAO1,ampC,,,,,,PHI:124179; PHI:124180; PHI:124181,287,Pseudomonas aeruginosa,208964; 652611,PAO1; PA14,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,beta-lactamase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene disruption,,,NN,36214681,PubMed,10.1128/spectrum.02700-22,Microbiol Spectr. 2022 Oct 26;10(5):e0270022. doi: 10.1128/spectrum.02700-22. Epub 2022 Oct 10,carlos.juan@ssib.es,Disruption of ampC in the PAΔDDh2Dh3 background (PAΔDDh2Dh3ΔAC) caused an almost full recovery of the wild-type (both strains).,I M Barceló 2022,2022,5 genes,Barcelo-2022-Role of Enzymatic Activity in the,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22058,PHI:124183,UniProt,Q9X3S5,GenBank,AAD21100,,,PAO1,ampG,,,,,,,287,Pseudomonas aeruginosa,208964; 652611,PAO1; PA14,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,permease for ampC beta-lactamase expression ampG,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene disruption,,,NN,36214681,PubMed,10.1128/spectrum.02700-22,Microbiol Spectr. 2022 Oct 26;10(5):e0270022. doi: 10.1128/spectrum.02700-22. Epub 2022 Oct 10,carlos.juan@ssib.es,Absolute LD50 values increased in ΔampG compared with those in the both strains.,I M Barceló 2022,2022,5 genes,Barcelo-2022-Role of Enzymatic Activity in the,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22059,PHI:124184,UniProt,E0SMH0,GenBank,ADN00609,,,3937,VfmE (WP_013320004.1),,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Russet,,,tuber,effector protein,,,quorum-sensing pathway,effector (plant avirulence determinant),,,,,reduced necrosis,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35352959,PubMed,10.1128/spectrum.01805-21,Microbiol Spectr. 2022 Apr 27;10(2):e0180521. doi: 10.1128/spectrum.01805-21. Epub 2022 Mar 30,chyang@uwm.edu,Reduced necrosis of potato tissues in the ΔvfmE single deletion mutant,B Banerjee 2022,2022,2 genes,Banerjee-2022-Quorum-Sensing Master Regulator,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22060,PHI:124185,,no data found,,,,,,ecpC,,,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Russet,,,tuber,effector protein,,,quorum-sensing pathway,effector (plant avirulence determinant),,,,,reduced necrosis,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35352959,PubMed,10.1128/spectrum.01805-21,Microbiol Spectr. 2022 Apr 27;10(2):e0180521. doi: 10.1128/spectrum.01805-21. Epub 2022 Mar 30,chyang@uwm.edu,ΔecpC showed reduced necrotic tissue formation compared to the WT in potato,B Banerjee 2022,2022,2 genes,Banerjee-2022-Quorum-Sensing Master Regulator,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22061,PHI:124184,UniProt,E0SMH0,GenBank,ADN00609,,,3937,VfmE (WP_013320004.1),,,,,,PHI:124185,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Russet,,,tuber,effector protein,,,quorum-sensing pathway,effector (plant avirulence determinant),,,,,reduced necrosis,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35352959,PubMed,10.1128/spectrum.01805-21,Microbiol Spectr. 2022 Apr 27;10(2):e0180521. doi: 10.1128/spectrum.01805-21. Epub 2022 Mar 30,chyang@uwm.edu,More necrosis was observed in the ΔvfmE ΔecpC double mutant.,B Banerjee 2022,2022,2 genes,Banerjee-2022-Quorum-Sensing Master Regulator,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22062,PHI:124185,,no data found,,,,,,ecpC,,,,,,PHI:124184,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Russet,,,tuber,effector protein,,,quorum-sensing pathway,effector (plant avirulence determinant),,,,,reduced necrosis,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35352959,PubMed,10.1128/spectrum.01805-21,Microbiol Spectr. 2022 Apr 27;10(2):e0180521. doi: 10.1128/spectrum.01805-21. Epub 2022 Mar 30,chyang@uwm.edu,More necrosis was observed in the ΔvfmE ΔecpC double mutant.,B Banerjee 2022,2022,2 genes,Banerjee-2022-Quorum-Sensing Master Regulator,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22063,PHI:124184,UniProt,E0SMH0,GenBank,ADN00609,,,3937,VfmE (WP_013320004.1),,vfmER93D,,,,,204038,Dickeya dadantii,198628,3937,soft rot,eudicots,4113,Solanum tuberosum (related: potato),cv. Russet,,,tuber,effector protein,,,quorum-sensing pathway,effector (plant avirulence determinant),,,,,reduced necrosis,,,,,no,,,,,,,gene mutation; gene complementation,,,NN,35352959,PubMed,10.1128/spectrum.01805-21,Microbiol Spectr. 2022 Apr 27;10(2):e0180521. doi: 10.1128/spectrum.01805-21. Epub 2022 Mar 30,chyang@uwm.edu,Reduced necrosis of potato tissues in the vfmER93D mutation mutant.,B Banerjee 2022,2022,2 genes,Banerjee-2022-Quorum-Sensing Master Regulator,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22064,PHI:124186,UniProt,A0A0A2JDH6,GenBank,KGO53424,,,MD-8,Erg4A (XP_016596026.1),,,,,,,27334,Penicillium expansum,,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious; cv. Fuji,,,fruit,ergosterol biosynthesis ERG4,,,,unaffected pathogenicity,,,,,wild type,reduced,,wild type,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233279,PubMed,10.3390/jof9050568,J Fungi (Basel). 2023 May 13;9(5):568. doi: 10.3390/jof9050568,xuehuali77@sina.com,"Results indicated that the deletion of erg4A, had no significant effect on the pathogenicity of P. expansum on the apple fruit.",Z Han 2023,2023,3 genes,Han-2023-Erg4 Is Involved in Ergosterol Biosyn,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22065,PHI:124187,UniProt,A0A0A2KM75,GenBank,KGO60095,,,MD-8,Erg4B (XP_016601169.1),,,,,,,27334,Penicillium expansum,,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious; cv. Fuji,,,fruit,ergosterol biosynthesis ERG4,,,,unaffected pathogenicity,,,,,wild type,reduced,,wild type,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233279,PubMed,10.3390/jof9050568,J Fungi (Basel). 2023 May 13;9(5):568. doi: 10.3390/jof9050568,xuehuali77@sina.com,"Results indicated that the deletion of erg4B, had no significant effect on the pathogenicity of P. expansum on the apple fruit.",Z Han 2023,2023,3 genes,Han-2023-Erg4 Is Involved in Ergosterol Biosyn,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22066,PHI:124188,UniProt,A0A0A2JAD5,GenBank,KGO49572,,,MD-8,Erg4C (XP_016592982.1),,,,,,,27334,Penicillium expansum,,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Golden Delicious; cv. Fuji,,,fruit,ergosterol biosynthesis ERG4,,,,unaffected pathogenicity,,,,,wild type,reduced,,wild type,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233279,PubMed,10.3390/jof9050568,J Fungi (Basel). 2023 May 13;9(5):568. doi: 10.3390/jof9050568,xuehuali77@sina.com,"Results indicated that the deletion of erg4C, had no significant effect on the pathogenicity of P. expansum on the apple fruit.",Z Han 2023,2023,3 genes,Han-2023-Erg4 Is Involved in Ergosterol Biosyn,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22067,PHI:124189,UniProt,G4MY99,GenBank,EHA55234,,,70-15,CEP1 (MGG_08086),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233285,PubMed,10.3390/jof9050574,J Fungi (Basel). 2023 May 15;9(5):574. doi: 10.3390/jof9050574,luxunli@cau.edu.cn,ΔMocep1 exhibited normal virulence as P131.,D Liu 2023,2023,5 genes,Liu-2023-Identification and Characterization o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22068,PHI:124190,UniProt,G4N5C1,GenBank,EHA52978,,,70-15,CEP2 (MGG_05232),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233285,PubMed,10.3390/jof9050574,J Fungi (Basel). 2023 May 15;9(5):574. doi: 10.3390/jof9050574,luxunli@cau.edu.cn,Deletion mutant of MoCEP2 showed reduced virulence on rice and barley plants,D Liu 2023,2023,5 genes,Liu-2023-Identification and Characterization o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22069,PHI:124191,UniProt,G4N6S9,GenBank,EHA49896,,,70-15,CEP3 (MGG_03671),chromosome 4,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233285,PubMed,10.3390/jof9050574,J Fungi (Basel). 2023 May 15;9(5):574. doi: 10.3390/jof9050574,luxunli@cau.edu.cn,Deletion mutant of MoCEP3 showed reduced virulence on rice and barley plants,D Liu 2023,2023,5 genes,Liu-2023-Identification and Characterization o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22070,PHI:124192,UniProt,G4MY32,GenBank,EHA53560,,,70-15,CEP5 (MGG_15401),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233285,PubMed,10.3390/jof9050574,J Fungi (Basel). 2023 May 15;9(5):574. doi: 10.3390/jof9050574,luxunli@cau.edu.cn,Deletion mutant of MoCEP5 showed reduced virulence on rice and barley plants,D Liu 2023,2023,5 genes,Liu-2023-Identification and Characterization o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22071,PHI:124193,UniProt,G4N375,GenBank,EHA52631,,,70-15,CEP7 (MGG_04944),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233285,PubMed,10.3390/jof9050574,J Fungi (Basel). 2023 May 15;9(5):574. doi: 10.3390/jof9050574,luxunli@cau.edu.cn,ΔMocep7 exhibited normal virulence as P131.,D Liu 2023,2023,5 genes,Liu-2023-Identification and Characterization o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22072,PHI:124189,UniProt,G4MY99,GenBank,EHA55234,,,70-15,CEP1 (MGG_08086),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233285,PubMed,10.3390/jof9050574,J Fungi (Basel). 2023 May 15;9(5):574. doi: 10.3390/jof9050574,luxunli@cau.edu.cn,ΔMocep1 exhibited normal virulence as P131.,D Liu 2023,2023,5 genes,Liu-2023-Identification and Characterization o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22073,PHI:124190,UniProt,G4N5C1,GenBank,EHA52978,,,70-15,CEP2 (MGG_05232),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233285,PubMed,10.3390/jof9050574,J Fungi (Basel). 2023 May 15;9(5):574. doi: 10.3390/jof9050574,luxunli@cau.edu.cn,Deletion mutant of MoCEP2 showed reduced virulence on rice and barley plants,D Liu 2023,2023,5 genes,Liu-2023-Identification and Characterization o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22074,PHI:124191,UniProt,G4N6S9,GenBank,EHA49896,,,70-15,CEP3 (MGG_03671),chromosome 4,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233285,PubMed,10.3390/jof9050574,J Fungi (Basel). 2023 May 15;9(5):574. doi: 10.3390/jof9050574,luxunli@cau.edu.cn,Deletion mutant of MoCEP3 showed reduced virulence on rice and barley plants,D Liu 2023,2023,5 genes,Liu-2023-Identification and Characterization o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22075,PHI:124192,UniProt,G4MY32,GenBank,EHA53560,,,70-15,CEP5 (MGG_15401),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233285,PubMed,10.3390/jof9050574,J Fungi (Basel). 2023 May 15;9(5):574. doi: 10.3390/jof9050574,luxunli@cau.edu.cn,Deletion mutant of MoCEP5 showed reduced virulence on rice and barley plants,D Liu 2023,2023,5 genes,Liu-2023-Identification and Characterization o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22076,PHI:124193,UniProt,G4N375,GenBank,EHA52631,,,70-15,CEP7 (MGG_04944),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37233285,PubMed,10.3390/jof9050574,J Fungi (Basel). 2023 May 15;9(5):574. doi: 10.3390/jof9050574,luxunli@cau.edu.cn,ΔMocep7 exhibited normal virulence as P131.,D Liu 2023,2023,5 genes,Liu-2023-Identification and Characterization o,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22077,PHI:124194,UniProt,A0A1D8PMJ9,GenBank,AOW29370,,,SC5314,TCA17 (C4_06460C),chromosome 4,,,,,,5476,Candida albicans,,AHY940,disseminated candidiasis,primates,9606,Homo sapiens (related: human),VK2/E6E7 cell line,,,VK-2/E6E7 cell,transport protein particle (TRAPP) complex-associated protein,,,secretory pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37222596,PubMed,10.1128/spectrum.05361-22,Microbiol Spectr. 2023 Jun 15;11(3):e0536122. doi: 10.1128/spectrum.05361-22. Epub 2023 May 24,samuel.a.lee@dartmouth.edu,Deletion of C. albicans TCA17 is associated with reduced virulence.,D Ma 2023,2023,1 gene,Ma-2023-A C. albicans TRAPP Complex-Associated,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22078,PHI:124195,UniProt,E4TAU0,GenBank,RA0C_1563,,,,feoA (RA0C_RS07485),,,,,,PHI:124196,34085,Riemerella anatipestifer,693978,ATCC 11845,fibrinous serositis; caseous salpingitis; vegetative disorder,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; brain; heart,ferrous iron transport protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37272830,PubMed,10.1128/spectrum.01373-23,Microbiol Spectr. 2023 Jun 5:e0137323. doi: 10.1128/spectrum.01373-23. Online ahead of print,chenganchun@vip.163.com,"ΔfeoAB strain of R. anatipestifer ATCC 11845 was significantly impaired in its ability to colonize the blood, liver, and brain of ducklings.",M Huang 2023,2023,2 genes,Huang-2023-Functional Characterization of FeoA,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22079,PHI:124196,UniProt,H8MC65,GenBank,RA0C_1564,,,,feoB (RA0C_RS07490),,,,,,PHI:124195,34085,Riemerella anatipestifer,693978,ATCC 11845,fibrinous serositis; caseous salpingitis; vegetative disorder,birds,8839,Anas platyrhynchos (related: mallard),,,,blood; liver; brain; heart,ferrous iron transport protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37272830,PubMed,10.1128/spectrum.01373-23,Microbiol Spectr. 2023 Jun 5:e0137323. doi: 10.1128/spectrum.01373-23. Online ahead of print,chenganchun@vip.163.com,"ΔfeoAB strain of R. anatipestifer ATCC 11845 was significantly impaired in its ability to colonize the blood, liver, and brain of ducklings.",M Huang 2023,2023,2 genes,Huang-2023-Functional Characterization of FeoA,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22080,PHI:124199,UniProt,A0A8H4FD53,GenBank,XP_045256765.1,,,,lac13,,,,,,,474922,Colletotrichum gloeosporioides,,A2,fruit rot,eudicots,29780,Mangifera indica (related: mango),cv. Tainung 1,,,,laccase gene,,,,reduced virulence,,,,,smaller lesions,increased,,reduced,increased,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37233214,PubMed,10.3390/jof9050503,J Fungi (Basel). 2023 Apr 23;9(5):503. doi: 10.3390/jof9050503,cataspjj@163.com,"Knockout of Cglac13 delaying the mycelial growth and ultimately, leading to a significant reduction in the pathogenicity in mango fruit.",M Zhang 2023,2023,1 gene,Zhang-2023-The Involvement of the Laccase Gene,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22081,PHI:124200,UniProt,A0A1D8PLL3,GenBank,AOW29025,,,SC5314,Ume7,chromosome 4,,,,,,5476,Candida albicans,294748,WO-1,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,DNA-binding transcriptional regulator,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37303958,PubMed,10.17912/micropub.biology.000826,MicroPubl Biol. 2023 May 25;2023:10.17912/micropub.biology.000826. doi: 10.17912/micropub.biology.000826. eCollection 2023,dabernstein@bsu.edu,"ume7 Δ/Δ had a modest defect in virulence, P value 0.0052.",B Evans 2023,2023,1 gene,Evans-2023-C. albicans UME7 deletion does not,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22082,PHI:124200,UniProt,A0A1D8PLL3,GenBank,AOW29025,,,SC5314,Ume7,chromosome 4,"inserting a stop codon at codon 376, ume7-376",,,,,5476,Candida albicans,294748,WO-1,disseminated candidiasis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,DNA-binding transcriptional regulator,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,NN,37303958,PubMed,10.17912/micropub.biology.000826,MicroPubl Biol. 2023 May 25;2023:10.17912/micropub.biology.000826. doi: 10.17912/micropub.biology.000826. eCollection 2023,dabernstein@bsu.edu,ume7-376 had no defect in virulence.,B Evans 2023,2023,1 gene,Evans-2023-C. albicans UME7 deletion does not,BATCH_123B,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22083,PHI:124201,UniProt,A0A384K5Y8,GenBank,ATZ58250,,,B05.10,mdl1,chromosome BCIN16,,,,,,40559,Botrytis cinerea,,HBTom-400,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,mitochondrial inner membrane ABC transporter,,,,reduced virulence,,,,,smaller lesions,reduced,,wild type,wild type,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37318357,PubMed,10.1128/spectrum.00108-23,Microbiol Spectr. 2023 Jun 15:e0010823,cxluo@mail.hzau.edu.cn,Reductions in conidial germination and virulence were observed in Bcmdl1 knockout transformants compared to the parental isolate and complemented transformants.,F Fan 2023,2023,1 gene,Fan-2023-Mitochondrial Inner Membrane ABC Tran,BATCH_124A,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22084,PHI:124202,,no data found,,,,,,baeS (AUO97_RS03400),,Mutation in BaeS (D89V),,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,two-component regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,NN,37345941,PubMed,10.1128/msystems.01291-22,mSystems. 2023 Jun 22:e0129122.,xiaotinghua@zju.edu.cn,"The strain with the BaeS (D89V) mutation appeared to be significantly more virulent, as less than half of the larvae survived 72 h post-infection (P = 0.0087).",X Liu 2023,2023,2 genes,Liu-2023-Mutation in the two-component regulat,BATCH_124A,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22085,PHI:124203,,no data found,,,,,,BaeR (AUO97_RS03395),,Mutation in BaeR (S104N),,,,,470,Acinetobacter baumannii,400667,ATCC 17978,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,two-component regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene mutation,,,NN,37345941,PubMed,10.1128/msystems.01291-22,mSystems. 2023 Jun 22:e0129122.,xiaotinghua@zju.edu.cn,ATCC 17978 BaeRS104N showed similar virulence as ATCC 17978 (P = 0.3379).,X Liu 2023,2023,2 genes,Liu-2023-Mutation in the two-component regulat,BATCH_124A,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22086,PHI:124204,UniProt,A0A8E5HSC9,GenBank,QUC20279,,,UV-8b,Snf1 (Uv8b_04520),chromosome 4,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,sucrose non-fermenting protein kinase,,,,increased virulence (hypervirulence),,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37450576,PubMed,10.1080/21505594.2023.2235460,Virulence. 2023 Dec;14(1):2235460. doi: 10.1080/21505594.2023.2235460,kouyanjun@caas.cn,Panicles inoculated with the ΔUvsnf1 mutants formed much fewer (approximately 78%) smut balls than those of the WT and ΔUvsnf1-C strains.,H Wen 2023,2023,3 genes,Wen-2023-Sucrose non-fermenting protein kinase,BATCH_124A,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22087,PHI:124205,UniProt,A0A8E5HQL5,GenBank,QUC19583,,,UV-8b,Cut1 (Uv8b_03824),chromosome 3,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,cell wall degrading enzymes,,,,increased virulence (hypervirulence),,,,,,reduced,,increased,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37450576,PubMed,10.1080/21505594.2023.2235460,Virulence. 2023 Dec;14(1):2235460. doi: 10.1080/21505594.2023.2235460,kouyanjun@caas.cn,"Rice spikelets inoculated with mutants failed to form smut balls, whereas there were various typical smut balls on the panicles inoculated with the WT and complementation strains.",H Wen 2023,2023,3 genes,Wen-2023-Sucrose non-fermenting protein kinase,BATCH_124A,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22088,PHI:124206,UniProt,A0A063BZ95,GenBank,GAO15939,,,IPU010,Xyp1 (Uv8b_02447),,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,panicle,cell wall degrading enzymes,,,,increased virulence (hypervirulence),,,,,,reduced; defective,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37450576,PubMed,10.1080/21505594.2023.2235460,Virulence. 2023 Dec;14(1):2235460. doi: 10.1080/21505594.2023.2235460,kouyanjun@caas.cn,"Rice spikelets inoculated with mutants failed to form smut balls, whereas there were various typical smut balls on the panicles inoculated with the WT and complementation strains.",H Wen 2023,2023,3 genes,Wen-2023-Sucrose non-fermenting protein kinase,BATCH_124A,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22089,PHI:124207,,no data found,,,,,,lygA (LMxysn_1092),,,,,,,1639,Listeria monocytogenes,,XYSN,listeriosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; liver; colon; brain,domain-containing autolysin protein,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37379353,PubMed,10.1371/journal.ppat.1011482,PLoS Pathog. 2023 Jun 28;19(6):e1011482. doi: 10.1371/journal.ppat.1011482. eCollection 2023 Jun,yylan@yzu.edu.cn,No deaths were recorded for ΔlygA mutant.,H Yao 2023,2023,1 gene,Yao-2023-LygA retention on the surface of List,BATCH_124A,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22090,PHI:124208,UniProt,K3V429,GenBank,EKJ67604,,,CS3096,Ume18 (FPSE_12218),,,,,,,101028,Fusarium pseudograminearum,,WZ-8A,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Aikang 58,,,coleoptile,transcription factor,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37446163,PubMed,10.3390/ijms241310987,Int J Mol Sci. 2023 Jul 1;24(13):10987. doi: 10.3390/ijms241310987,li@henau.edu.cn,"ΔFpume18 deletion mutant showed defects in growth, conidial production, conidial germination and virulence.",Y Zhang 2023,2023,1 gene,Zhang-2023-A Putative Zn(II)(2)Cys(6)-Type Tra,BATCH_124A,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22091,PHI:124210,UniProt,Q63XK2,GenBank,CAH34527,,,K96243,KdsD (BPSL0538),chromosome 1,,,,,,28450,Burkholderia pseudomallei,272560,K96243,melioidosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,spleen,arabinose 5-phosphate isomerase,,,,loss of pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37458584,PubMed,10.1128/jb.00034-23,J Bacteriol. 2023 Jul 17:e0003423. doi: 10.1128/jb.00034-23. Online ahead of print,cjenkins@dstl.gov.uk,"Deletion of kdsD resulted in growth defects, loss of motility, reduced survival in RAW 264.7 murine macrophages, and attenuation in a BALB/ c mouse model of melioidosis.",C H Jenkins 2023,2023,1 gene,Jenkins-2023-The Arabinose 5-Phosphate Isomera,BATCH_124A,2023-07-01,MC,,,,,,,,,,,,,
,,Record 22092,PHI:124211,UniProt,E0W4U2,GenBank,AEK81300,,,P7064,Avh413,,,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),var. Huachun 6,,,hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37386076,PubMed,10.1038/s41564-023-01420-z,Nat Microbiol. 2023 Jun 29. doi,qyl588@gmail.com,PsAvh413 deletion mutant showed moderately slower growth in vitro but significantly reduced disease symptoms and P. sojae biomass on soybean seedlings.,X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae boosts host trehal,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22093,PHI:124211,UniProt,E0W4U2,GenBank,AEK81300,,,P7064,Avh413,,,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37386076,PubMed,10.1038/s41564-023-01420-z,Nat Microbiol. 2023 Jun 29,qyl588@gmail.com,Lesion size were significantly greater on N. benthamiana leaves expressing PsAvh413 than the EV control.,X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae boosts host trehal,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22094,PHI:124211,UniProt,E0W4U2,GenBank,AEK81300,,,P7064,Avh413,,Ser77 and Ser111 substituted with alanine,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,reduced,,no,,,,,,,gene mutation,,,NN,37386076,PubMed,10.1038/s41564-023-01420-z,Nat Microbiol. 2023 Jun 29,qyl588@gmail.com,PsAvh413M reduced its virulence function in N. benthamiana leaves,X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae boosts host trehal,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22095,PHI:124211,UniProt,E0W4U2,GenBank,AEK81300,,,P7064,Avh413,,,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37386076,PubMed,10.1038/s41564-023-01420-z,Nat Microbiol. 2023 Jun 29,qyl588@gmail.com,Lesion size were significantly greater on Seedlings expressing PsAvh413 than the EV control.,X Zhu 2023,2023,1 gene,Zhu-2023-Phytophthora sojae boosts host trehal,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22096,PHI:124212,UniProt,P67347,GenBank,AAL22246,,,LT2,msrP,,,,,,,28901,Salmonella enterica,,subsp. enterica serovar Typhimurium strain E-5591,salmonellosis,rodents,10090,Mus musculus (related: house mouse),Swiss albino,,,spleen; liver,periplasmic methionine sulfoxide reductase,,,,reduced virulence,,,,,,,,wild type,,no,HOCl,HOCl: CHEBI:24757,,,,,gene deletion: full,,,NN,37403401,PubMed,10.1093/femsle/fnad063,FEMS Microbiol Lett. 2023 Jul 4:fnad063,manishbiochemistry@gmail.com,Mutant strain showed very mild defect in survival in mice spleen and liver as compared to wild type strain.,H B Chandra 2023,2023,1 gene,Chandra-2023-Periplasmic methionine sulfoxide,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22097,PHI:124213,UniProt,A0A384K4A6,GenBank,ATZ57474,,,B05.10,Bcest (Bcin15g00520),chromosome BCIN15,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,29760,Vitis vinifera (related: wine grape),,,,fruit; leaf,membrane protein,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,SDS; H2O2; KCl,SDS: CHEBI:8984; H2O2: CHEBI:16240; KCl: CHEBI:32588,,,,,gene deletion: full; gene complementation,,,NN,37317199,PubMed,10.3390/microorganisms11051225,Microorganisms. 2023 May 6;11(5):1225,shiliming@caas.cn,"Deletion of Bcest showed defects in aspects of mycelial growth, conidiation and virulence.",W Zhang 2023,2023,1 gene,Zhang-2023-Membrane Protein Bcest Is Involved,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22098,PHI:124214,UniProt,A0A6C0ZR57,GenBank,QIC90961,,,Q07-21,mshA,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,mshA knockout mutant did not show a significant difference in colonization of the intestinal environment during either competition.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22099,PHI:124215,UniProt,A0A2S1ZTY7,GenBank,AWK28906,,,R-5879,mshH,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,mshH was outcompeted by the wild-type strain in adult mice.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22100,PHI:124215,UniProt,A0A2S1ZTY7,GenBank,AWK28906,,,R-5879,mshH,,Plac-mshH fragment integrated into lacZ locus of ΔmshH mutant,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,ΔmshHCmshH did not show a significant difference in colonization.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22101,PHI:124216,,no data found,,,,,,csrC,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,"csrC deletion mutant showed a competition advantage against the wild-type strain at day 1 and day 3, and it colonized as well as the wild type at day2.",M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22102,PHI:124215,UniProt,A0A2S1ZTY7,GenBank,AWK28906,,,R-5879,mshH,,,,,,PHI:124217; PHI:124218,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,ΔmshH\ΔcsrB/D mutant made a significant recovery compared with that of the ΔmshH mutant.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22103,PHI:124217,,no data found,,,,,,csrB,,,,,,PHI:124215; PHI:124218,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,ΔmshH\ΔcsrB/D mutant made a significant recovery compared with that of the ΔmshH mutant.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22104,PHI:124218,UniProt,A0A7Z7YD78,,,,,,csrD,,,,,,PHI:124215; PHI:124217,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,ΔmshH\ΔcsrB/D mutant made a significant recovery compared with that of the ΔmshH mutant.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22105,PHI:124215,UniProt,A0A2S1ZTY7,GenBank,AWK28906,,,R-5879,mshH,,,,,,PHI:124216; PHI:124217; PHI:124218,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,The quadruple mutant (ΔmshHΔcsrB/C/D) showed a severe colonization defect in adult mouse intestine.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22106,PHI:124216,,no data found,,,,,,csrC,,,,,,PHI:124215; PHI:124217; PHI:124218,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,The quadruple mutant (ΔmshHΔcsrB/C/D) showed a severe colonization defect in adult mouse intestine.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22107,PHI:124217,,no data found,,,,,,csrB,,,,,,PHI:124215; PHI:124216; PHI:124218,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,The quadruple mutant (ΔmshHΔcsrB/C/D) showed a severe colonization defect in adult mouse intestine.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22108,PHI:124218,UniProt,A0A7Z7YD78,,,,,,csrD,,,,,,PHI:124215; PHI:124216; PHI:124217,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,The quadruple mutant (ΔmshHΔcsrB/C/D) showed a severe colonization defect in adult mouse intestine.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22109,PHI:124219,UniProt,H6BAI9,GenBank,AEI83800,,,344-17,toxR,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,regulatory protein,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,toxR showed a significant colonization defect against the wild-type strain.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22110,PHI:124220,UniProt,B2CKP2,GenBank,ACB30337,,,P27459,hapR,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,regulatory protein,,,mshH-csrB/C/D-csrA regulatory pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,The hapR knockout mutant colonized adult mice as well as the wild-type.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22111,PHI:124215,UniProt,A0A2S1ZTY7,GenBank,AWK28906,,,R-5879,mshH,,Plac-toxR fragment integrated into lacZ locus of ΔmshH mutant,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,The colonization ability of the ΔmshHCtoxR mutant recovered comparable to that of the ΔmshH mutant at day 3.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22112,PHI:124220,UniProt,B2CKP2,GenBank,ACB30337,,,P27459,hapR,,,,,,PHI:124215,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,regulatory protein,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,Deletion of hapR in the ΔmshH mutant could not restore the colonization defect of ΔmshH mutant.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22113,PHI:124215,UniProt,A0A2S1ZTY7,GenBank,AWK28906,,,R-5879,mshH,,,,,,PHI:124220,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,Deletion of hapR in the ΔmshH mutant could not restore the colonization defect of ΔmshH mutant.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22114,PHI:124221,UniProt,P0C6Q6,GenBank,AAF93799,,,N16961,ompU,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,regulatory protein,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,Deletion of ompU showed a significant colonization defect against the wild-type strain.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22115,PHI:124222,UniProt,O86021,GenBank,AAC28105,,,0395,ompT,,,,,,,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,regulatory protein,,,mshH-csrB/C/D-csrA regulatory pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,ompT knockout mutant colonized adult mice as well as the wild type.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22116,PHI:124215,UniProt,A0A2S1ZTY7,GenBank,AWK28906,,,R-5879,mshH,,Plac-ompU fragment integrated into lacZ locus of ΔmshHΔompT mutant,,,,PHI:124222,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,csr sRNA,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,Competitive indexes of ΔmshHΔ ompTCompU versus the wild type were significantly increased compared with that of ΔmshH versus the wild type.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22117,PHI:124222,UniProt,O86021,GenBank,AAC28105,,,0395,ompT,,Plac-ompU fragment integrated into lacZ locus of ΔmshHΔompT mutant,,,,PHI:124215,666,Vibrio cholerae,948564,C6706,cholera,rodents,10090,Mus musculus (related: house mouse),ICR,,,Intestine,regulatory protein,,,mshH-csrB/C/D-csrA regulatory pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37404138,PubMed,10.1128/aem.00561-23,Appl Environ Microbiol. 2023 Jul 5:e0056123,yangmh@zafu.edu.cn,Competitive indexes of ΔmshHΔ ompTCompU versus the wild type were significantly increased compared with that of ΔmshH versus the wild type.,M Shi 2023,2023,9 genes,Shi-2023-Precisely Controlling Csr sRNA Levels,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22118,PHI:124223,UniProt,A0A7U7JDS8,GenBank,CEJ16859,,,IPO1609,RipAS,,,,,,,305,Ralstonia solanacearum,342110,UW551,bacterial wilt,eudicots,4113,Solanum tuberosum (related: potato),cv. E-Potato 3,,,seedling,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37334181,PubMed,10.1093/hr/uhad087,Hortic Res. 2023 May 3;10(6):uhad087,songbotao@mail.hzau.edu.cn,Transgenic lines expressing RipAS were challenged with R. solanacearum UW551 and showed enhanced disease symptoms.,B Wang 2023,2023,1 gene,Wang-2023-Ralstonia solanacearum type III effe,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22119,PHI:124224,UniProt,A0A1D8PHV2,GenBank,AOW27714,,,SC5314,smf12,chromosome 2,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen,NRAMP transporter,,,secretory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37363924,PubMed,10.1371/journal.ppat.1011478,PLoS Pathog. 2023 Jun 26;19(6):e1011478,vculott1@jhu.edu,Mice infected with the smf12Δ/Δ mutant had a statistically significant increase in median survival time of 16 days.,A S Wildeman 2023,2023,2 genes,Wildeman-2023-The role of manganese in morphog,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22120,PHI:124225,UniProt,A0A1D8PFT1,,,,,,smf13,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen,NRAMP transporter,,,secretory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37363924,PubMed,10.1371/journal.ppat.1011478,PLoS Pathog. 2023 Jun 26;19(6):e1011478,vculott1@jhu.edu,Mice infected with the smf13Δ/Δ mutant had a statistically significant increase in median survival time of 21.5 days.,A S Wildeman 2023,2023,2 genes,Wildeman-2023-The role of manganese in morphog,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22121,PHI:124224,UniProt,A0A1D8PHV2,GenBank,AOW27714,,,SC5314,smf12,chromosome 2,,,,,PHI:124225,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen,NRAMP transporter,,,secretory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37363924,PubMed,10.1371/journal.ppat.1011478,PLoS Pathog. 2023 Jun 26;19(6):e1011478,vculott1@jhu.edu,"Double smf12Δ/Δ smf13Δ/Δ shows a further decrease in virulence, particularly in comparison to the smf12Δ/Δ mutant.",A S Wildeman 2023,2023,2 genes,Wildeman-2023-The role of manganese in morphog,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22122,PHI:124225,UniProt,A0A1D8PFT1,,,,,,smf13,,,,,,PHI:124224,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen,NRAMP transporter,,,secretory pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37363924,PubMed,10.1371/journal.ppat.1011478,PLoS Pathog. 2023 Jun 26;19(6):e1011478,vculott1@jhu.edu,"Double smf12Δ/Δ smf13Δ/Δ shows a further decrease in virulence, particularly in comparison to the smf12Δ/Δ mutant.",A S Wildeman 2023,2023,2 genes,Wildeman-2023-The role of manganese in morphog,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22123,PHI:124226,UniProt,Q9RMI5,GenBank,AAF05823,,,MC2 155,furA,,,,,,,1772,Mycolicibacterium smegmatis,246196,MC2 155,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,ferric uptake regulator,,,,increased virulence (hypervirulence),,,,,,,,reduced,,no,,,,,,,gene mutation,,,NN,37358434,PubMed,10.1128/spectrum.05367-22,Microbiol Spectr. 2023 Jun 26:e0536722,wangbn@im.ac.cn,"60% of the mice survived in the furA infection 4 days after the intravenous challenge, and 100% survived the mc2115 infection.",X Fan 2023,2023,1 gene,Fan-2023-Coevolution of furA-Regulated Hyper-I,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22124,PHI:124227,UniProt,S8GK08,GenBank,EPT32205,,,ME49,GRA83 (TGME49_297900),chromosome II,,,,,,5811,Toxoplasma gondii,,PruΔKu80Δhxgprt,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung; brain,granule protein,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37398161,PubMed,10.1101/2023.05.31.543158,bioRxiv. 2023 Jun 1:2023.05.31.543158,pbradley@ucla.edu,"Disruption of GRA83 results in increased virulence, weight loss, and parasitemia.",A C Thind 2023,2023,1 gene,Thind-2023-The Toxoplasma gondii effector GRA8,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22125,PHI:124228,UniProt,A0A7V9W6U0,GenBank,MBC9074695,,,NLA000701671,phoP,,,,,,PHI:124229,78331,Mycobacterium canettii,,STB-K,tuberculosis,primates,9606,Homo sapiens (related: human),HMDM cells,,,macrophage,two-component system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37450466,PubMed,10.1371/journal.ppat.1011437,PLoS Pathog. 2023 Jul 14;19(7):e1011437,Lionel.Mourey@ipbs.fr,Percentage of infected cells was significantly lower for STB-KR and the STB-KR ΔphoPR::hyg mutant.,W Malaga 2023,2023,2 genes,Malaga-2023-Natural mutations in the sensor ki,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22126,PHI:124229,UniProt,A0A8I0JYC1,GenBank,MBC9074696,,,NLA000701671,phoR,,,,,,PHI:124228,78331,Mycobacterium canettii,,STB-K,tuberculosis,primates,9606,Homo sapiens (related: human),HMDM cells,,,macrophage,two-component system,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37450466,PubMed,10.1371/journal.ppat.1011437,PLoS Pathog. 2023 Jul 14;19(7):e1011437,Lionel.Mourey@ipbs.fr,Percentage of infected cells was significantly lower for STB-KR and the STB-KR ΔphoPR::hyg mutant.,W Malaga 2023,2023,2 genes,Malaga-2023-Natural mutations in the sensor ki,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22127,PHI:124228,UniProt,A0A7V9W6U0,GenBank,MBC9074695,,,NLA000701671,phoP,,,,,,PHI:124229,78331,Mycobacterium canettii,,STB-K,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C3HeB/FeJ,,,lung; spleen,two-component system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37450466,PubMed,10.1371/journal.ppat.1011437,PLoS Pathog. 2023 Jul 14;19(7):e1011437,Lionel.Mourey@ipbs.fr,"Low bacterial load of the ΔphoPR::hyg mutant, inflammatory lesions were detectable in mice.",W Malaga 2023,2023,2 genes,Malaga-2023-Natural mutations in the sensor ki,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22128,PHI:124229,UniProt,A0A8I0JYC1,GenBank,MBC9074696,,,NLA000701671,phoR,,,,,,PHI:124228,78331,Mycobacterium canettii,,STB-K,tuberculosis,rodents,10090,Mus musculus (related: house mouse),C3HeB/FeJ,,,lung; spleen,two-component system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37450466,PubMed,10.1371/journal.ppat.1011437,PLoS Pathog. 2023 Jul 14;19(7):e1011437,Lionel.Mourey@ipbs.fr,"Low bacterial load of the ΔphoPR::hyg mutant, inflammatory lesions were detectable in mice.",W Malaga 2023,2023,2 genes,Malaga-2023-Natural mutations in the sensor ki,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22129,PHI:124230,UniProt,P50334,GenBank,CAA62742,,,LT2,dctA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,rodents,10090,Mus musculus (related: house mouse),J774 cell line,,,macrophage,primary dicarboxylate importer,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,33593945,PubMed,10.1128/JB.00487-20,J Bacteriol. 2021 May 1;203(9):e00487-20,william.navarre@utoronto.ca,No decrease in survival relative to that of wild-type Salmonella in mouse (J774) macrophage cell lines.,S J Hersch 2021,2021,1 gene,Hersch-2021-A stress-induced block in dicarbox,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22130,PHI:124230,UniProt,P50334,GenBank,CAA62742,,,LT2,dctA,,,,,,,28901,Salmonella enterica,90371,subsp. enterica serovar Typhimurium strain ATCC 14028s,salmonellosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,primary dicarboxylate importer,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,33593945,PubMed,10.1128/JB.00487-20,J Bacteriol. 2021 May 1;203(9):e00487-20,william.navarre@utoronto.ca,No decrease in survival relative to that of wild-type Salmonella in THP-1 macrophage cell lines.,S J Hersch 2021,2021,1 gene,Hersch-2021-A stress-induced block in dicarbox,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22131,PHI:124231,UniProt,A0A194W6B7,GenBank,KUI71623,,,03-8,VM1G_06867,chromosome 7,,,,,,105487,Valsa mali,,11-175,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit; twig,transcription factor,,,cyclic adenosine signaling pathway,reduced virulence,,,,,reduced lesions,increased; defective,,reduced,reduced,no,sorbitol; NaCl; sucrose; sodium dodecyl sulphate (SDS); tebuconazole; glucose; Congo red; calcofluor white (CFW),sorbitol: CHEBI:30911; NaCl: CHEBI:26710; sucrose: CHEBI:17992; sodium dodecyl sulphate (SDS): CHEBI:8984; tebuconazole: CHEBI:81781; glucose: CHEBI:17234; Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full; gene complementation,,,NN,37367628,PubMed,10.3390/jof9060692,J Fungi (Basel). 2023 Jun 20;9(6):692,lidc@sdau.edu.cn,Lengths of the lesions on the apple fruit with VM1G_06867 deletion mutant had decreased by approximately 10.8% compared and 12.6% on twigs compared with the WT.,Y Diao 2023,2023,2 genes,Diao-2023-Transcription Factor VM1G_06867_ A R,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22132,PHI:124232,,no data found,,,,,,Som1,,,,,,,105487,Valsa mali,,11-175,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit; twig,transcription factor,,,cyclic adenosine signaling pathway,reduced virulence,,,,,reduced lesions,reduced; defective,,reduced,reduced,no,sorbitol; NaCl; sucrose; sodium dodecyl sulphate (SDS); tebuconazole; glucose; Congo red; calcofluor white (CFW),sorbitol: CHEBI:30911; NaCl: CHEBI:26710; sucrose: CHEBI:17992; sodium dodecyl sulphate (SDS): CHEBI:8984; tebuconazole: CHEBI:81781; glucose: CHEBI:17234; Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,37367628,PubMed,10.3390/jof9060692,J Fungi (Basel). 2023 Jun 20;9(6):692,lidc@sdau.edu.cn,ΔVmSom1 reduces the diameter of apple fruit and twigs spots by 75.9%.,Y Diao 2023,2023,2 genes,Diao-2023-Transcription Factor VM1G_06867_ A R,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22133,PHI:124231,UniProt,A0A194W6B7,GenBank,KUI71623,,,03-8,VM1G_06867,chromosome 7,,,,,PHI:124232,105487,Valsa mali,,11-175,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit; twig,transcription factor,,,cyclic adenosine signaling pathway,reduced virulence,,,,,reduced lesions,reduced; defective,,reduced,reduced,no,sorbitol; NaCl; sucrose; sodium dodecyl sulphate (SDS); tebuconazole; glucose; Congo red; calcofluor white (CFW),sorbitol: CHEBI:30911; NaCl: CHEBI:26710; sucrose: CHEBI:17992; sodium dodecyl sulphate (SDS): CHEBI:8984; tebuconazole: CHEBI:81781; glucose: CHEBI:17234; Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,37367628,PubMed,10.3390/jof9060692,J Fungi (Basel). 2023 Jun 20;9(6):692,lidc@sdau.edu.cn,Double deletion mutant Δ VmSom1/06867 reduces the diameter of apple fruit and twigs spots by 79.9%.,Y Diao 2023,2023,2 genes,Diao-2023-Transcription Factor VM1G_06867_ A R,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22134,PHI:124232,,no data found,,,,,,Som1,,,,,,PHI:124231,105487,Valsa mali,,11-175,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit; twig,transcription factor,,,cyclic adenosine signaling pathway,reduced virulence,,,,,reduced lesions,reduced; defective,,reduced,reduced,no,sorbitol; NaCl; sucrose; sodium dodecyl sulphate (SDS); tebuconazole; glucose; Congo red; calcofluor white (CFW),sorbitol: CHEBI:30911; NaCl: CHEBI:26710; sucrose: CHEBI:17992; sodium dodecyl sulphate (SDS): CHEBI:8984; tebuconazole: CHEBI:81781; glucose: CHEBI:17234; Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,37367628,PubMed,10.3390/jof9060692,J Fungi (Basel). 2023 Jun 20;9(6):692,lidc@sdau.edu.cn,Double deletion mutant Δ VmSom1/06867 reduces the diameter of apple fruit and twigs spots by 79.9%.,Y Diao 2023,2023,2 genes,Diao-2023-Transcription Factor VM1G_06867_ A R,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22135,PHI:124233,UniProt,P0A917,GenBank,AAA66329,,,K-12,ompX,,,,,,,562,Escherichia coli,199310,CFT073,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,Bladder,outer membrane protein,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,33753414,PubMed,10.1128/IAI.00721-20,Infect Immun. 2021 May 17;89(6):e00721-20,hirakawa@gunma-u.ac.jp,No statistical difference was observed in the numbers of bacteria in the bladder between the ompX mutant and the parent strain.,H Hirakawa 2021,2021,2 genes,"Hirakawa-2021-Roles of OmpX, an outer membrane",BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22136,PHI:124233,UniProt,P0A917,GenBank,AAA66329,,,K-12,ompX,,,,,,,562,Escherichia coli,199310,CFT073,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,kidney,outer membrane protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,33753414,PubMed,10.1128/IAI.00721-20,Infect Immun. 2021 May 17;89(6):e00721-20,hirakawa@gunma-u.ac.jp,Mice infected with the ompX mutant exhibited lower UPEC burdens in the kidneys than those infected with the parent strain.,H Hirakawa 2021,2021,2 genes,"Hirakawa-2021-Roles of OmpX, an outer membrane",BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22137,PHI:124233,UniProt,P0A917,GenBank,AAA66329,,,K-12,ompX,,,,,,PHI:124234,562,Escherichia coli,199310,CFT073,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,kidney,outer membrane protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,33753414,PubMed,10.1128/IAI.00721-20,Infect Immun. 2021 May 17;89(6):e00721-20,hirakawa@gunma-u.ac.jp,Deletion of ompX in the fliC mutant did not further decrease the bacterial internalization rate within kidney epithelial cells compared to ompX mutant.,H Hirakawa 2021,2021,2 genes,"Hirakawa-2021-Roles of OmpX, an outer membrane",BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22138,PHI:124234,UniProt,P04949,GenBank,CAA35488,,,K-12,fliC,,,,,,PHI:124233,562,Escherichia coli,199310,CFT073,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),C3H/HeN,,,kidney,outer membrane protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,33753414,PubMed,10.1128/IAI.00721-20,Infect Immun. 2021 May 17;89(6):e00721-20,hirakawa@gunma-u.ac.jp,Deletion of ompX in the fliC mutant did not further decrease the bacterial internalization rate within kidney epithelial cells compared to ompX mutant.,H Hirakawa 2021,2021,2 genes,"Hirakawa-2021-Roles of OmpX, an outer membrane",BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22139,PHI:124235,UniProt,J4W2U0,GenBank,EJP64740,,,ARSEF 2860,FlrA (BBA_06309),chromosome unknown,,,fluG (BBA_04942),UniProt: J5JTS0; GenBank: EJP65971,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative glutamine synthetase,,,central developmental pathway,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; menadione; Congo red; calcofluor white (CFW),sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; menadione: CHEBI:28869; Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,35862810,PubMed,10.1128/msystems.00318-22,mSystems. 2022 Aug 30;7(4):e0031822.,mgfeng@zju.edu.cn,The flrA mutant caused mean mortalities of 60% compared with wild type 100% mortality.,C T Guo 2022,2022,2 genes,Guo-2022-FluG and FluG-like FlrA Coregulate Ma,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22140,PHI:124235,UniProt,J4W2U0,GenBank,EJP64740,,,ARSEF 2860,FlrA (BBA_06309),chromosome unknown,,,fluG (BBA_04942),UniProt: J5JTS0; GenBank: EJP65971,PHI:124236,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative glutamine synthetase,,,central developmental pathway,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; menadione; Congo red; calcofluor white (CFW),sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; menadione: CHEBI:28869; Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,35862810,PubMed,10.1128/msystems.00318-22,mSystems. 2022 Aug 30;7(4):e0031822.,mgfeng@zju.edu.cn,The double disruption mutant caused mean mortalities of 10% compared with wild type 100% mortality.,C T Guo 2022,2022,2 genes,Guo-2022-FluG and FluG-like FlrA Coregulate Ma,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22141,PHI:124236,UniProt,J5JTS0,GenBank,EJP65971,,,ARSEF 2860,fluG (BBA_04942),chromosome unknown,,,,,PHI:124235,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,putative glutamine synthetase,,,central developmental pathway,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; KCl; menadione; Congo red; calcofluor white (CFW),sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; KCl: CHEBI:32588; menadione: CHEBI:28869; Congo red: CHEBI:34653; calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,35862810,PubMed,10.1128/msystems.00318-22,mSystems. 2022 Aug 30;7(4):e0031822.,mgfeng@zju.edu.cn,The double disruption mutant caused mean mortalities of 10% compared with wild type 100% mortality.,C T Guo 2022,2022,2 genes,Guo-2022-FluG and FluG-like FlrA Coregulate Ma,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22142,PHI:124237,UniProt,A0A1D8PRM0,GenBank,AOW30790,,,SC5314,ngs1,chromosome R,,,,,,5476,Candida albicans,,SN250,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,gut,GlcNAc sensor-transducer,,,GlcNAc kinase,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37365160,PubMed,10.1038/s41467-023-39284-w,Nat Commun. 2023 Jun 26;14(1):3796,ylu7@whu.edu.cn,Mice infected with the wild type died observable faster than that infected with the mutant one.,D Yang 2023,2023,1 gene,Yang-2023-Candida albicans exploits N-acetylgl,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22143,PHI:124238,,no data found,,,,,,Gar (PXO_RS11965),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,increased,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full; gene complementation,,,NN,37436661,PubMed,10.1007/s00284-023-03396-9,Curr Microbiol. 2023 Jul 12;80(9):279. doi: 10.1007/s00284-023-03396-9,ruanlifang@mail.hzau.edu.cn,The lesion length caused by Δgar was longer compared to wild-type PXO99A,H Wang 2023,2023,2 genes,Wang-2023-A transcriptional Regulator Gar Regu,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22144,PHI:124238,,no data found,,,,,,Gar (PXO_RS11965),,,,,,PHI:124239,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,NN,37436661,PubMed,10.1007/s00284-023-03396-9,Curr Microbiol. 2023 Jul 12;80(9):279. doi: 10.1007/s00284-023-03396-9,ruanlifang@mail.hzau.edu.cn,Bacterial growth under H2O2 stress and the virulence of Δgar was restored in the rpoN2 overexpressing strain.,H Wang 2023,2023,2 genes,Wang-2023-A transcriptional Regulator Gar Regu,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22145,PHI:124239,,no data found,,,,,,rpoN2 (PXO_RS12900 ),,,,,,PHI:124238,347,Xanthomonas oryzae,360094,pv. oryzae strain PXO99A,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24 line,,,leaf,transcriptional regulator,,,,reduced virulence,,,,,,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,altered gene expression / gene regulation: overexpression,,,NN,37436661,PubMed,10.1007/s00284-023-03396-9,Curr Microbiol. 2023 Jul 12;80(9):279. doi: 10.1007/s00284-023-03396-9,ruanlifang@mail.hzau.edu.cn,Bacterial growth under H2O2 stress and the virulence of Δgar was restored in the rpoN2 overexpressing strain.,H Wang 2023,2023,2 genes,Wang-2023-A transcriptional Regulator Gar Regu,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22146,PHI:124240,UniProt,Q87DU4,GenBank,AAO28459,,,Temecula1,CutC (PD0586),,,,,,,2371,Xylella fastidiosa,183190,TemeculaL,Pierce's disease of grapes; Citrus variegated chlorosis,eudicots,4097,Nicotiana tabacum (related: common tobacco),cv. Petit Havana SR1,,,leaf,copper-binding protein,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35196066,PubMed,10.1094/PHYTO-11-21-0488-R,Phytopathology. 2022 Aug;112(8):1620-1629. doi: 10.1094/PHYTO-11-21-0488-R. Epub 2022 Jun 17,lzd0005@auburn.edu,CutC mutant showed decreased disease incidence and severity compared with WT.,Q Ge 2022,2022,1 gene,Ge-2022-The copper-binding protein CutC is inv,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22147,PHI:124241,UniProt,P0AER8,GenBank,BAA00517,,,B,gltS,,,,,,,562,Escherichia coli,364106,UTI89,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,Bladder; kidney,glutamate transporters,,,glutamate metabolic pathway,reduced virulence,,,,,,,,wild type,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full; gene complementation,,,NN,37317147,PubMed,10.3390/microorganisms11051173,Microorganisms. 2023 Apr 29;11(5):1173,yzhang207@zju.edu.cn,UTI89 deletion mutant ΔgltS had significantly lower bacterial load than those of the parent strain UTI89 at all the time points post infection.,H Niu 2023,2023,3 genes,"Niu-2023-Glutamate Transporters GltS, GltP and",BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22148,PHI:124242,UniProt,P21345,GenBank,AAA24323,,,K-12,gltP,,,,,,,562,Escherichia coli,364106,UTI89,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,Bladder; kidney,glutamate transporters,,,glutamate metabolic pathway,reduced virulence,,,,,,,,wild type,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full; gene complementation,,,NN,37317147,PubMed,10.3390/microorganisms11051173,Microorganisms. 2023 Apr 29;11(5):1173,yzhang207@zju.edu.cn,UTI89 deletion mutant ΔgltP had significantly lower bacterial load than those of the parent strain UTI89 at all the time points post infection.,H Niu 2023,2023,3 genes,"Niu-2023-Glutamate Transporters GltS, GltP and",BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22149,PHI:124243,UniProt,P37902,GenBank,AAC73756,,,K-12,gltI,,,,,,,562,Escherichia coli,364106,UTI89,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,Bladder; kidney,glutamate transporters,,,glutamate metabolic pathway,reduced virulence,,,,,,,,wild type,,no,gentamicin,gentamicin: CHEBI:17833,,,,,gene deletion: full; gene complementation,,,NN,37317147,PubMed,10.3390/microorganisms11051173,Microorganisms. 2023 Apr 29;11(5):1173,yzhang207@zju.edu.cn,UTI89 deletion mutant ΔgltI had significantly lower bacterial load than those of the parent strain UTI89 at all the time points post infection.,H Niu 2023,2023,3 genes,"Niu-2023-Glutamate Transporters GltS, GltP and",BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22150,PHI:124244,UniProt,A7F4R9,GenBank,EDN97740,,,1980,pde2,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,phosphodiesterase,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37324679,PubMed,10.3389/fpls.2023.1175552,Front Plant Sci. 2023 May 31;14:1175552,xinli@msl.ubc.ca,"SsPDE2 in Arabidopsis thaliana, largely compromised virulence was observed against S. sclerotiorum.",Y Xu 2023,2023,1 gene,Xu-2023-A cAMP phosphodiesterase is essential,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22151,PHI:124244,UniProt,A7F4R9,GenBank,EDN97740,,,1980,pde2,,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaf,phosphodiesterase,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37324679,PubMed,10.3389/fpls.2023.1175552,Front Plant Sci. 2023 May 31;14:1175552,xinli@msl.ubc.ca,"SsPDE2 in Nicotiana benthamiana, largely compromised virulence was observed against S. sclerotiorum.",Y Xu 2023,2023,1 gene,Xu-2023-A cAMP phosphodiesterase is essential,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22152,PHI:124245,UniProt,A0A482PJF2,GenBank,QBY30858,,,DBS100,nanT,,,,,,,67825,Citrobacter rodentium,,DBS100,,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,Intestine,sialic acid transporter,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37399418,PubMed,10.1073/pnas.2301115120,Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2301115120,hby@mail.ubc.ca,ΔnanT C. rodentium strain was significantly impaired in its ability to colonize the murine intestine.,Q Liang 2023,2023,1 gene,Liang-2023-Sialic acid plays a pivotal role in,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22153,PHI:124246,UniProt,G2X495,GenBank,EGY23539,,,VdLs.17,EPG1,,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Jimian 11,,,seedling; root,endopolygalacturonase,,,,reduced virulence,,,yes,,low disease severity,reduced,,reduced,,no,sorbitol; NaCl; KCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; NaCl: CHEBI:26710; KCl: CHEBI:32588; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,gene deletion: full; gene complementation,,,NN,37401912,PubMed,10.1111/mpp.13366,Mol Plant Pathol. 2023 Jul 4,fenghongjie@caas.cn,Knocking out VdEPG1 led to a significant decrease in the pathogenicity of V. dahliae in cotton.,S Liu 2023,2023,1 gene,Liu-2023-The glycoside hydrolase 28 member VdE,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22154,PHI:124247,UniProt,S7W455,GenBank,EPR59698,,,GT1,MORN2 (TGGT1_292120),,,,Reticulon (TgRTN) and β-Tubulin,UniProt: A0A125YHI4; GenBank: EPR62258,,5811,Toxoplasma gondii,,RHΔKu80,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,MORN family protein,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37373373,PubMed,10.3390/ijms241210228,Int J Mol Sci. 2023 Jun 16;24(12):10228,tzhangxiao@sdau.edu.cn,Genetic deletion of MORN2 did not noticeably affect parasite growth and virulence.,J Li 2023,2023,1 gene,"Li-2023-TgMORN2, a MORN Family Protein Involve",BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22155,PHI:124248,UniProt,Q9UW03,GenBank,CAB52402,,,SAS56,atrB,,,,,,,40559,Botrytis cinerea,,AI18,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,efflux transporter,,,,reduced virulence,,,,,smaller lesions,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37332725,PubMed,10.3389/fpls.2023.1177060,Front Plant Sci. 2023 Jun 2;14:1177060,dtakemo@agr.nagoya-u.ac.jp,ΔbcatrB showed reduced virulence on tomato.,A S Bulasag 2023,2023,1 gene,Bulasag-2023-Botrytis cinerea tolerates phytoa,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22156,PHI:124248,UniProt,Q9UW03,GenBank,CAB52402,,,SAS56,atrB,,,,,,,40559,Botrytis cinerea,,AI18,grey mold,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,efflux transporter,,,,unaffected pathogenicity,,,,,wild type,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37332725,PubMed,10.3389/fpls.2023.1177060,Front Plant Sci. 2023 Jun 2;14:1177060,dtakemo@agr.nagoya-u.ac.jp,No significant differences were observed between wild type and ΔbcatrB strains in the lesion formation on bell pepper fruits.,A S Bulasag 2023,2023,1 gene,Bulasag-2023-Botrytis cinerea tolerates phytoa,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22157,PHI:124248,UniProt,Q9UW03,GenBank,CAB52402,,,SAS56,atrB,,,,,,,40559,Botrytis cinerea,,AI18,grey mold,eudicots,57577,Trifolium pratense (related: rotklee),,,,leaf,efflux transporter,,,,reduced virulence,,,,,wild type,reduced,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37332725,PubMed,10.3389/fpls.2023.1177060,Front Plant Sci. 2023 Jun 2;14:1177060,dtakemo@agr.nagoya-u.ac.jp,"Compared to the wild type strain, the ΔbcatrB strain resulted in lower lesion scores indicating that BcatrB is required for full virulence on red clover.",A S Bulasag 2023,2023,1 gene,Bulasag-2023-Botrytis cinerea tolerates phytoa,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22158,PHI:124249,,no data found,,,,,,FGSG 03445,,,,,,,5518,Fusarium graminearum,,,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. AC Walton,,,seedling; leaf; spikelet,CRISPR/cas9-mediated gene,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37367609,PubMed,10.3390/jof9060673,J Fungi (Basel). 2023 Jun 14;9(6):673,adam.foster2@agr.gc.ca,No statistically significant differences were observed for virulence.,A J Foster 2023,2023,2 genes,Foster-2023-Unanticipated Large-Scale Deletion,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22159,PHI:124250,UniProt,I1RVG3,,,,,,FGSG 08238,,,,,,,5518,Fusarium graminearum,,,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. AC Walton,,,seedling; leaf; spikelet,CRISPR/cas9-mediated gene,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37367609,PubMed,10.3390/jof9060673,J Fungi (Basel). 2023 Jun 14;9(6):673,adam.foster2@agr.gc.ca,No statistically significant differences were observed for virulence.,A J Foster 2023,2023,2 genes,Foster-2023-Unanticipated Large-Scale Deletion,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22160,PHI:124251,UniProt,E3QMS8,GenBank,EFQ32166,,,M1.001,ALA1 (GLRG_07310.1),,,,,,,31870,Colletotrichum graminicola,,CgM2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf,allantoicase,,,,reduced virulence,,,,,smaller lesions,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,NN,32687013,PubMed,10.1094/PHYTO-04-20-0114-R,Phytopathology. 2020 Sep;110(9):1530-1540,ch.glienke@gmail.com,Ala1 deletion strain showed virulence defects.,E H Benatto Perino 2020,2020,2 genes,Benatto Perino-2020-Molecular Characterization,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22161,PHI:124252,UniProt,E3Q4H7,GenBank,EFQ25489,,,M1.001,URE1(GLRG_00633.1),,,,,,,31870,Colletotrichum graminicola,,CgM2,stalk rot (maize); leaf blight (maize),monocots,4577,Zea mays (related: maize),cv. Mikado,,,leaf,urease,,,,reduced virulence,,,,,smaller lesions,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,NN,32687013,PubMed,10.1094/PHYTO-04-20-0114-R,Phytopathology. 2020 Sep;110(9):1530-1540,ch.glienke@gmail.com,Ure1 deletion strain showed virulence defects.,E H Benatto Perino 2020,2020,2 genes,Benatto Perino-2020-Molecular Characterization,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22162,PHI:124253,UniProt,G7ZU80,GenBank,CCC18657,,,EHEC FE94097,stx1,,,,,,,562,Escherichia coli,,UC4224,neonatal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,Shiga toxin gene,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37426006,PubMed,10.3389/fmicb.2023.1156375,Front Microbiol. 2023 Jun 23;14:1156375,pier.cocconcelli@unicatt.it,"Mortality rate of Δstx1 was significantly lower than UC4224 (p < 0.05) for the three lowest doses injected, with a LD50 of 81.7 CFU/10μL.",G Milani 2023,2023,2 genes,Milani-2023-Genome engineering of Stx1-and Stx,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22163,PHI:124254,UniProt,Q8XBV2,,,,,,stx2,,,,,,,562,Escherichia coli,,UC4224,neonatal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,Shiga toxin gene,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37426006,PubMed,10.3389/fmicb.2023.1156375,Front Microbiol. 2023 Jun 23;14:1156375,pier.cocconcelli@unicatt.it,"Mortality rate of Δstx2 was significantly lower than UC4224 (p < 0.05) for the three lowest doses injected, with a LD50 of 50.5 CFU/10μL.",G Milani 2023,2023,2 genes,Milani-2023-Genome engineering of Stx1-and Stx,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22164,PHI:124253,UniProt,G7ZU80,GenBank,CCC18657,,,EHEC FE94097,stx1,,,,,,PHI:124254,562,Escherichia coli,,UC4224,neonatal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,Shiga toxin gene,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37426006,PubMed,10.3389/fmicb.2023.1156375,Front Microbiol. 2023 Jun 23;14:1156375,pier.cocconcelli@unicatt.it,"The lethality rate of UC4178 (Δstx1 Δstx2) strain, with a LD50 of 582.7 CFU/10μL, was significantly lower than the parental strains",G Milani 2023,2023,2 genes,Milani-2023-Genome engineering of Stx1-and Stx,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22165,PHI:124254,UniProt,Q8XBV2,,,,,,stx2,,,,,,PHI:124253,562,Escherichia coli,,UC4224,neonatal meningitis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,Shiga toxin gene,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37426006,PubMed,10.3389/fmicb.2023.1156375,Front Microbiol. 2023 Jun 23;14:1156375,pier.cocconcelli@unicatt.it,"The lethality rate of UC4178 (Δstx1 Δstx2) strain, with a LD50 of 582.7 CFU/10μL, was significantly lower than the parental strains",G Milani 2023,2023,2 genes,Milani-2023-Genome engineering of Stx1-and Stx,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22166,PHI:124255,UniProt,A5CS01,GenBank,CAN01864,,,NCPPB 382,rel (CMM_1809),,,,,,,28447,Clavibacter michiganensis,,BT0505,bacterial canker,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,stem,GTP pyrophosphokinase,,,,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,35341314,PubMed,10.1094/PHYTO-01-22-0023-R,Phytopathology. 2022 Sep;112(9):1844-1858. doi,luolaixin@cau.edu.cn,Mutant rel showed reduced symptoms of disease in tomato.,K Bai 2022,2022,1 gene,Bai-2022-RNA-Seq Analysis Discovers the Critic,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22167,PHI:124256,UniProt,A0A654THK5,GenBank,CFE46791,,,G09901357,phoP,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36052440,PubMed,10.1080/21505594.2022.2119657,Virulence. 2022 Dec;13(1):1543-1557,m.asai16@imperial.ac.uk,"Larval challenge with ΔphoP led to significant (p < 0.0001) attenuation in virulence relative to the WT, with larval survival of 93% and 48%.",M Asai 2022,2022,2 genes,Asai-2022-Galleria mellonella as an infection,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22168,PHI:124257,UniProt,P9WMF9,GenBank,AAD17452,,,H37Rv,dosR,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,transcriptional regulator,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36052440,PubMed,10.1080/21505594.2022.2119657,Virulence. 2022 Dec;13(1):1543-1557,m.asai16@imperial.ac.uk,"Larval challenge with ΔdosR led to significant (p < 0.01) potentiation of virulence relative to WT, with larval survival of 30% and 53%.",M Asai 2022,2022,2 genes,Asai-2022-Galleria mellonella as an infection,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22169,PHI:124258,,no data found,,,,,,pae,,,,,,,287,Pseudomonas aeruginosa,1158200,TBCF10839,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,methyltransferase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,36106744,PubMed,10.1128/msystems.00434-22,mSystems. 2022 Oct 26;7(5):e0043422,liuy7@sustech.edu.cn,"20% of the larvae in TBCFΔpaeTBCFIIM group survived, while all larvae in the wild-type group and complemented-strain group had died.",S Han 2022,2022,1 gene,Han-2022-DNA Methyltransferase Regulates Nitri,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22170,PHI:124259,UniProt,Q2FFH4,GenBank,ABD22203,,,USA300_FPR3757,pgl (SAUSA300_1902),,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,bronchoalveolar lavage fluid; lung; spleen; skin,hypothetical protein,,,pentose phosphate pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation; gene complementation,,,NN,37440594,PubMed,10.1371/journal.ppat.1011531,PLoS Pathog. 2023 Jul 13;19(7):e1011531,dane.parker@rutgers.edu,"Significant decrease in bacterial spread to the lung, spleen and dermonecrosis were significantly reduced in skin.",J Kim 2023,2023,1 gene,Kim-2023-Impact of the pentose phosphate pathw,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22171,PHI:124260,,no data found,,,,,,GRA57,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,foreskin fibroblast cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37459303,PubMed,10.1371/journal.pbio.3002202,PLoS Biol. 2023 Jul 17;21(7):e3002202,moritz.treeck@crick.ac.uk,RHΔGRA57 parasites displayed a relative decrease in survival of 39% compared to RHΔUPRT controls.,E J Lockyer 2023,2023,3 genes,Lockyer-2023-A heterotrimeric complex of Toxop,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22172,PHI:124261,,no data found,,,,,,MYR3,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,foreskin fibroblast cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37459303,PubMed,10.1371/journal.pbio.3002202,PLoS Biol. 2023 Jul 17;21(7):e3002202,moritz.treeck@crick.ac.uk,RHΔGRA57 parasites displayed a relative decrease in survival of 68% compared to RHΔUPRT controls.,E J Lockyer 2023,2023,3 genes,Lockyer-2023-A heterotrimeric complex of Toxop,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22173,PHI:124262,,no data found,,,,,,MYR1,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,primates,9606,Homo sapiens (related: human),,,,foreskin fibroblast cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37459303,PubMed,10.1371/journal.pbio.3002202,PLoS Biol. 2023 Jul 17;21(7):e3002202,moritz.treeck@crick.ac.uk,RHΔGRA57 parasites displayed a relative decrease in survival of 84% compared to RHΔUPRT controls.,E J Lockyer 2023,2023,3 genes,Lockyer-2023-A heterotrimeric complex of Toxop,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22174,PHI:124260,,no data found,,,,,,GRA57,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),,,,embryonic fibroblast cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37459303,PubMed,10.1371/journal.pbio.3002202,PLoS Biol. 2023 Jul 17;21(7):e3002202,moritz.treeck@crick.ac.uk,RHΔGRA57 parasites displayed a relative decrease in survival of 11% compared to RHΔUPRT controls.,E J Lockyer 2023,2023,3 genes,Lockyer-2023-A heterotrimeric complex of Toxop,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22175,PHI:124261,,no data found,,,,,,MYR3,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),,,,embryonic fibroblast cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37459303,PubMed,10.1371/journal.pbio.3002202,PLoS Biol. 2023 Jul 17;21(7):e3002202,moritz.treeck@crick.ac.uk,RHΔGRA57 parasites displayed a relative decrease in survival of 31% compared to RHΔUPRT controls.,E J Lockyer 2023,2023,3 genes,Lockyer-2023-A heterotrimeric complex of Toxop,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22176,PHI:124262,,no data found,,,,,,MYR1,,,,,,,5811,Toxoplasma gondii,383379,RH,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),,,,embryonic fibroblast cell line,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37459303,PubMed,10.1371/journal.pbio.3002202,PLoS Biol. 2023 Jul 17;21(7):e3002202,moritz.treeck@crick.ac.uk,RHΔGRA57 parasites displayed a relative decrease in survival of 31% compared to RHΔUPRT controls.,E J Lockyer 2023,2023,3 genes,Lockyer-2023-A heterotrimeric complex of Toxop,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22177,PHI:124263,UniProt,P24474,GenBank,CAA34471,,,NCTC 6750,nirS,,,,,,,287,Pseudomonas aeruginosa,208964,PAO1,nosocomial infection,nematodes,6239,Caenorhabditis elegans (related: roundworm),N2,,,adult,nitrite reductase,,,denitrification pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37410300,PubMed,10.1007/s10123-023-00395-5,Int Microbiol. 2023 Jul 6,xjtan@ahnu.edu.cn,The lifespan of worms that fed on the pNirS strain was increased by 18% compared with that of worms that fed on the pEV strain for 5 days.,X Tan 2023,2023,1 gene,Tan-2023-Effects of elevated levels of intrace,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22178,PHI:124264,UniProt,Q5NEB6,GenBank,CAG46357,,,SCHU S4,TolC,,,,,,,263,Francisella tularensis,376619,LVS,tularemia,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,macrophage,outer membrane channel protein,,,TLR2-MYD88-p38 signaling pathway,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37404047,PubMed,10.1128/mbio.01136-23,mBio. 2023 Jul 5:e0113623,david.thanassi@stonybrook.edu,"WT mice infected with the WT LVS had a mean survival time of 7 d, whereas all WT mice infected with the ΔtolC mutant survived for the duration of the experiment.",P T Benziger 2023,2023,1 gene,Benziger-2023-Francisella tularensis disrupts,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22179,PHI:124265,UniProt,A0A8H7YJ94,GenBank,KAG5290802,,,G184AR,Pex5,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),P388D1 cell line; C57BL/6,,,macrophage; lung,peroxins,,,PTS1 pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37432032,PubMed,10.1128/mbio.03284-22,mBio. 2023 Jul 11:e0328422,rappleye.1@osu.edu,Loss of peroxisome protein import limited H. capsulatum intracellular growth in macrophages and attenuated virulence in an acute histoplasmosis infection model.,P J Brechting 2023,2023,4 genes,Brechting-2023-Histoplasma capsulatum requires,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22180,PHI:124266,UniProt,A0A8A1M026,GenBank,QSS59798,,,WU24,Pex10,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),P388D1 cell line; C57BL/6,,,macrophage; lung,peroxins,,,PTS1 pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37432032,PubMed,10.1128/mbio.03284-22,mBio. 2023 Jul 11:e0328422,rappleye.1@osu.edu,Loss of peroxisome protein import limited H. capsulatum intracellular growth in macrophages and attenuated virulence in an acute histoplasmosis infection model.,P J Brechting 2023,2023,4 genes,Brechting-2023-Histoplasma capsulatum requires,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22181,PHI:124267,,no data found,,,,,,Pex33,,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),P388D1 cell line; C57BL/6,,,macrophage; lung,peroxins,,,PTS1 pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37432032,PubMed,10.1128/mbio.03284-22,mBio. 2023 Jul 11:e0328422,rappleye.1@osu.edu,Loss of peroxisome protein import limited H. capsulatum intracellular growth in macrophages and attenuated virulence in an acute histoplasmosis infection model.,P J Brechting 2023,2023,4 genes,Brechting-2023-Histoplasma capsulatum requires,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22182,PHI:124268,UniProt,A0A8A1MP94,GenBank,QSS66462,,,WU24,Pex11,chromosome 3,,,,,,5037,Histoplasma capsulatum,447094,G217B,histoplasmosis,rodents,10090,Mus musculus (related: house mouse),P388D1 cell line; C57BL/6,,,macrophage; lung,peroxins,,,PTS1 pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37432032,PubMed,10.1128/mbio.03284-22,mBio. 2023 Jul 11:e0328422,rappleye.1@osu.edu,Loss of peroxisome protein import does nit limited H. capsulatum intracellular growth in macrophages and attenuated virulence in an acute histoplasmosis infection model.,P J Brechting 2023,2023,4 genes,Brechting-2023-Histoplasma capsulatum requires,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22183,PHI:124269,,no data found,,,,,,CrgA (RS_RS16695),,,,flhC; flhD,UniProt: A3RKQ1; GenBank: ABO13878; UniProt: A3RKQ0; GenBank: ABO13877,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Hong yangli,,,petiole; stem; leaf,transcriptional regulator,,,,reduced virulence,,,,,low disease severity,,,increased,,no,,,,,,,gene deletion: full; gene complementation,,,NN,33046561,PubMed,10.1128/JB.00419-20,J Bacteriol. 2020 Dec 7;203(1):e00419-20,hszou@fafu.edu.cn,The disease severity caused by the ΔcrgA mutant was lower than that of the wild type and the CΔcrgA mutant at 11 days postinoculation.,X Fan 2020,2020,1 gene,Fan-2020-The LysR-Type Transcriptional Regulat,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22184,PHI:124270,,no data found,,,,,,SPI-1,,,,,,,28901,Salmonella enterica,,subsp. enterica serovar Enteritidis strain C50041,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; spleen; cecum,Salmonella pathogenicity island 1 (SPI1) type III secretion systems,,,ERK/STAT2 phosphorylation,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37325511,PubMed,10.3389/fcimb.2023.1158888,Front Cell Infect Microbiol. 2023 May 30;13:1158888,jiao@yzu.edu.cn,20% of animals infected with the same dose of S. Enteritidis DSPI-1 died on the sixth day post- infection and 60% of mice succumbed to infection by the ninth day.,D Xiong 2023,2023,2 genes,Xiong-2023-Salmonella Enteritidis activates in,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22185,PHI:124271,,no data found,,,,,,SPI-2,,,,,,,28901,Salmonella enterica,,subsp. enterica serovar Enteritidis strain C50041,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; spleen; cecum,Salmonella pathogenicity island 2 (SPI 2) type III secretion systems,,,ERK/STAT2 phosphorylation,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37325511,PubMed,10.3389/fcimb.2023.1158888,Front Cell Infect Microbiol. 2023 May 30;13:1158888,jiao@yzu.edu.cn,No deaths were observed when mice were challenged with ΔSPI-2.,D Xiong 2023,2023,2 genes,Xiong-2023-Salmonella Enteritidis activates in,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22186,PHI:124270,,no data found,,,,,,SPI-1,,,,,,PHI:124271,28901,Salmonella enterica,,subsp. enterica serovar Enteritidis strain C50041,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; spleen; cecum,Salmonella pathogenicity island 1 (SPI1) type III secretion systems,,,ERK/STAT2 phosphorylation,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37325511,PubMed,10.3389/fcimb.2023.1158888,Front Cell Infect Microbiol. 2023 May 30;13:1158888,jiao@yzu.edu.cn,No deaths were observed when mice were challenged with ΔSPI-1/ SPI-2.,D Xiong 2023,2023,2 genes,Xiong-2023-Salmonella Enteritidis activates in,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22187,PHI:124271,,no data found,,,,,,SPI-2,,,,,,PHI:124270,28901,Salmonella enterica,,subsp. enterica serovar Enteritidis strain C50041,gastroenteritis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,liver; spleen; cecum,Salmonella pathogenicity island 2 (SPI 2) type III secretion systems,,,ERK/STAT2 phosphorylation,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37325511,PubMed,10.3389/fcimb.2023.1158888,Front Cell Infect Microbiol. 2023 May 30;13:1158888,jiao@yzu.edu.cn,No deaths were observed when mice were challenged with ΔSPI-1/ SPI-2.,D Xiong 2023,2023,2 genes,Xiong-2023-Salmonella Enteritidis activates in,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22188,PHI:124272,UniProt,G4N5L2,GenBank,EHA52205,,,70-15,smek1,chromosome 3,,,Crf1 (MGG_05709/XP_003710608); CreA (MGG_11201/XP_003714427),UniProt: G4MPF4; GenBank: EHA57996; UniProt: G4MSK4; GenBank: EHA54620,,318829,Magnaporthe oryzae,,,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,serine/threonine protein phosphatase regulatory subunit,,,L-arabinose metabolism pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,glycerol; ethanol; glucose,glycerol: CHEBI:17754; ethanol: CHEBI:16236; glucose: CHEBI:17234,,,,,gene deletion: full; gene complementation,,,NN,37357820,PubMed,10.1111/mpp.13368,Mol Plant Pathol. 2023 Jun 26,jplu@zju.edu.cn,The disease index of rice leaves infected by Δsmek1 was 34.7% of that of the wild type.,Z Huang 2023,2023,1 gene,Huang-2023-The triglyceride catabolism regulat,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22189,PHI:124273,UniProt,S7UPV8,GenBank,EPR59725,,,GT1,cpc1 (TGGT1_289620),,,,,,,5811,Toxoplasma gondii,,,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,cathepsin C-like protease,,,secretory pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full; gene complementation,,,NN,37326431,PubMed,10.1128/mbio.00174-23,mBio. 2023 Jun 16:e0017423,zdou@clemson.edu,The mice infected with Δcpc1 survived significantly longer than mice infected with WT or Δcpc1CPC1.,L B Thornton 2023,2023,1 gene,Thornton-2023-A cathepsin C-like protease medi,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22190,PHI:124274,UniProt,A7E9A5,GenBank,EDN96957,,,1980,SsNR (SS1G_01885),,,,,,,5180,Sclerotinia sclerotiorum,,FXGD2,white mold,eudicots,3847,Glycine max (related: soybean),,,,leaf,nitrate reductase,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: silencing,,,NN,37342142,PubMed,10.3389/fpls.2023.1096831,Front Plant Sci. 2023 Jun 5;14:1096831,yangguogen@ahau.edu.cn,Lesion size of mutants was much smaller (3.28%~4.73% and 14.39%~15.72%) than wild-type and mock strains.,J Wei 2023,2023,1 gene,Wei-2023-Nitrate reductase is required for scl,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22191,PHI:124274,UniProt,A7E9A5,GenBank,EDN96957,,,1980,SsNR (SS1G_01885),,,,,,,5180,Sclerotinia sclerotiorum,,FXGD2,white mold,eudicots,3708,Brassica napus (related: rape),,,,leaf,nitrate reductase,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,sorbitol; hydrogen peroxide (H2O2); NaCl; sodium dodecyl sulphate (SDS); Congo red,sorbitol: CHEBI:30911; hydrogen peroxide (H2O2): CHEBI:16240; NaCl: CHEBI:26710; sodium dodecyl sulphate (SDS): CHEBI:8984; Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: silencing,,,NN,37342142,PubMed,10.3389/fpls.2023.1096831,Front Plant Sci. 2023 Jun 5;14:1096831,yangguogen@ahau.edu.cn,Lesion size of mutants was much smaller (3.28%~4.73% and 14.39%~15.72%) than wild-type and mock strains.,J Wei 2023,2023,1 gene,Wei-2023-Nitrate reductase is required for scl,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22192,PHI:124275,UniProt,Q9P8P2,GenBank,AAF65220,,,H99,PLB1,,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,brain,phospholipase B,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation,,,NN,36786559,PubMed,10.1128/mbio.02640-22,mBio. 2023 Apr 25;14(2):e0264022,LMartinez@dental.ufl.edu,H99 strain showed significantly faster mortality than mice infected with the plb1 strain.,M F Hamed 2023,2023,1 gene,Hamed-2023-Phospholipase B Is Critical for Cry,BATCH_124B,2023-08-01,MC,,,,,,,,,,,,,
,,Record 22193,PHI:124276,UniProt,A0A1D9PT15,GenBank,APA05413,,,1980,SSA (sscle_01g001830),chromosome 1,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mold,eudicots,3708,Brassica napus (related: rape),cv. Zhongshuang 9,,,leaf,agglutinin protein,,,,increased virulence (hypervirulence),,,,,larger lesions,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);CaCl2;NaCl;KCl;sucrose;sodium dodecyl sulphate (SDS);mannitol,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sucrose: CHEBI:17992; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;mannitol: CHEBI:29864,,,,,gene deletion: full ; gene complementation,,,NN,37504726,PubMed,10.3390/jof9070737,J Fungi (Basel). 2023 Jul 10;9(7):737,yanglong@mail.hzau.edu.cn,"""The WT and the complementary mutant formed smaller lesions with average diameters of 22.2 and 22.9 mm than those of the lesions formed by the disruption mutant, which had average diameters ranging from 26.2 to 30.5 mm.""",Y Wang 2023,2023,1 gene,Wang-2023-Sclerotinia sclerotiorum Agglutinin,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22194,PHI:124277,UniProt,A0A0L0VX29,,,,,,CDA2 (Pst_02914),,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,yellow rust,monocots,4565,Triticum aestivum (related: bread wheat),,,,leaf,chitin deacetylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37486146,PubMed,10.1111/mpp.13381,Mol Plant Pathol. 2023 Jul 24,yyh023@swu.edu.cn,Fewer urediniospore pustules were produced on leaves inoculated with BSMV:PsCDA2 in comparison to control .,M Xiao 2023,2023,1 gene,Xiao-2023-A chitin deacetylase PsCDA2 from Puc,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22195,PHI:124278,UniProt,A0A8J5NM17,GenBank,KAG7407213,,,Tf1208,Rho2,,,,,,,5507,Fusarium oxysporum,,,Fusarium wilt,eudicots,44586,Panax notoginseng (related: tienchi),,,,stem; leaf,GTPase,,,mpk1 pathway,reduced virulence,,,,,no necrotic lesions,wild type,,wild type,reduced,no,sorbitol;CaCl2;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,37548840,PubMed,10.1007/s11274-023-03720-2,World J Microbiol Biotechnol. 2023 Aug 7;39(10):272.,nianhongjuan@163.com,"P. notoginseng inoculated with the WT strain showed characteristic wilt and necrotic, however, P. notoginseng inoculated with the Δrho2 mutant strain appeared healthy.",J Liu 2023,2023,1 gene,"Liu-2023-Rho2 involved in development, stress",BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22196,PHI:124279,UniProt,A0A2H3G405,GenBank,CAG1986094,,,MDC_Fg202,Gcn5,,,,Ubp14; Tom1,UniProt: A0A2H3H0N3; GenBank: CAG1961155,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; leaf,histone acetyltransferase,,,autophagy pathway,loss of pathogenicity,,,,,no visible disease,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37504517,PubMed,10.1128/mbio.01499-23,mBio. 2023 Aug 31;14(4):e0149923,chenyun0927@zju.edu.cn,Deletion of Gcn5 led to a reduction in vegetative growth and loss of F. graminearum virulence.,A Chen 2023,2023,3 genes,Chen-2023-Ubiquitination of acetyltransferase,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22197,PHI:124280,UniProt,A0A2H3H0N3,GenBank,CAG1961155,,,MDC_Fg851,Ubp14 (FGRAMPH1_01G06337),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; leaf,deubiquitinating enzyme,,,autophagy pathway,loss of pathogenicity,,,yes,,no visible disease,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37504517,PubMed,10.1128/mbio.01499-23,mBio. 2023 Aug 31;14(4):e0149923,chenyun0927@zju.edu.cn,Deletion of Ubp14 led to a reduction in vegetative growth and loss of F. graminearum virulence.,A Chen 2023,2023,3 genes,Chen-2023-Ubiquitination of acetyltransferase,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22198,PHI:124281,UniProt,I1RAU6,,,,,,Tom1 (FGRAMPH1_01G01601),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; leaf,E3 ligase,,,autophagy pathway,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37504517,PubMed,10.1128/mbio.01499-23,mBio. 2023 Aug 31;14(4):e0149923,chenyun0927@zju.edu.cn,Loss of Tom1 affects the fungal development and virulence of F. graminearum.,A Chen 2023,2023,3 genes,Chen-2023-Ubiquitination of acetyltransferase,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22199,PHI:124279,UniProt,A0A2H3G405,GenBank,CAG1986094,,,MDC_Fg202,Gcn5,,Gcn5K252R,,Ubp14; Tom1,UniProt: A0A2H3H0N3; GenBank: CAG1961155,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,spike; leaf,histone acetyltransferase,,,autophagy pathway,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene mutation,,,NN,37504517,PubMed,10.1128/mbio.01499-23,mBio. 2023 Aug 31;14(4):e0149923,chenyun0927@zju.edu.cn,Deletion of Gcn5 led to a reduction in vegetative growth and loss of F. graminearum virulence.,A Chen 2023,2023,3 genes,Chen-2023-Ubiquitination of acetyltransferase,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22200,PHI:124282,UniProt,H1VS96,GenBank,CCF43104,,,IMI 349063,URA3 (CH63R_12904),,,,,,,80884,Colletotrichum higginsianum,,,anthracnose; leaf spot,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,transcription factor,,,melanin biosynthesis pathway,loss of pathogenicity,,,,,no lesion,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37522511,PubMed,10.1111/mpp.13378,Mol Plant Pathol. 2023 Jul 31,ken.shirasu@riken.jp,"The inoculation of wild-type C. higginsianum caused brownish anthracnose disease symptoms, whereas no symptoms were observed in the ura3 mutant.",K Yonehara 2023,2023,1 gene,Yonehara-2023-Efficient multiple gene knockout,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22201,PHI:124283,UniProt,E1WAC8,GenBank,AAA75170,,,SL1344,SPI-1,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,birds,9031,Gallus gallus (related: chicken),,,,cecum; liver,Salmonella pathogenicity islands 1,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,gene deletion: full,,,NN,37490241,PubMed,10.1007/s11259-023-10185-z,Vet Res Commun. 2023 Jul 25,luary@unam.mx,Organs of chickens infected with ΔSPI-1 showed attenuated lesions and the immunohistochemistry revealed less bacteria compared to the WT strain.,J T Pico-Rodríguez 2023,2023,2 genes,Pico-Rodr?guez-2023-Effect of Salmonella patho,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22202,PHI:124284,UniProt,O84947,GenBank,CAA12187,,,LT2,SPI-2,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,birds,9031,Gallus gallus (related: chicken),,,,cecum; liver,Salmonella pathogenicity islands 1,,,,reduced virulence,,,,,,,,defective,,no,,,,,,,gene deletion: full,,,NN,37490241,PubMed,10.1007/s11259-023-10185-z,Vet Res Commun. 2023 Jul 25,luary@unam.mx,Organs of chickens infected with ΔSPI-2 showed attenuated lesions and the immunohistochemistry revealed less bacteria compared to the WT strain.,J T Pico-Rodríguez 2023,2023,2 genes,Pico-Rodr?guez-2023-Effect of Salmonella patho,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22203,PHI:124285,UniProt,C0LEX7,GenBank,ACN54417,,,W1,pilA,,,,,,,80869,Paracidovorax citrulli,,Aac5; pslb65,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),cv. Jingxin 3,,,leaf; seedling,type IV pili,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37512977,PubMed,10.3390/microorganisms11071806,Microorganisms. 2023 Jul 14;11(7):1806,yangyuwen@caas.cn,pilA deletion mutants (Aac5-ΔpilA) and (pslb65-ΔpilA) showed significantly reduced pathogenicity compared with the wild-type (WT) strains.,Y Yang 2023,2023,1 gene,Yang-2023-pilA Gene Contributes to Virulence,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22204,PHI:124285,UniProt,C0LEX7,GenBank,ACN54417,,,W1,pilA,,,,,,,80869,Paracidovorax citrulli,,Aac5; pslb65,bacterial fruit blotch,eudicots,3656,Cucumis melo (related: muskmelon),TVF192,,,leaf,type IV pili,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37512977,PubMed,10.3390/microorganisms11071806,Microorganisms. 2023 Jul 14;11(7):1806,yangyuwen@caas.cn,pilA deletion mutants (Aac5-ΔpilA) and (pslb65-ΔpilA) showed significantly reduced pathogenicity compared with the wild-type (WT) strains.,Y Yang 2023,2023,1 gene,Yang-2023-pilA Gene Contributes to Virulence,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22205,PHI:124286,UniProt,A0A384J4J4,GenBank,ATZ45444,,,B05.10,TSP3,chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,tetraspanin 3,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37474601,PubMed,10.1038/s41467-023-40093-4,Nat Commun. 2023 Jul 20;14(1):4383,hailingj@ucr.edu,Infection with Δbctsp3 resulted in lesions similar to the wild-type strain.,B He 2023,2023,2 genes,He-2023-Fungal small RNAs ride in extracellula,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22206,PHI:124287,UniProt,Q8J0E3,,,,,,PLS1,,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,punchless 1,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37474601,PubMed,10.1038/s41467-023-40093-4,Nat Commun. 2023 Jul 20;14(1):4383,hailingj@ucr.edu,The Δbcpls1 mutant strain showed a significant reduction in virulence with the lesion size being reduced by 84% compared with the wild-type strain.,B He 2023,2023,2 genes,He-2023-Fungal small RNAs ride in extracellula,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22207,PHI:124288,UniProt,G4N4M5,GenBank,EHA52040,,,70-15,Nem1 (MGG_06001),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,lipid droplet-associated protein,,,cAMP-PKA signaling pathway,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);rapamycin;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;rapamycin: CHEBI:9168; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,37581021,PubMed,10.1007/s42994-023-00098-5,aBIOTECH. 2023 Feb 18;4(2):108-123,chenxiaolin@mail.hzau.edu.cn,The Δnem1 mutant was nearly loss of virulence to host plants due to defects in appressorial penetration and invasive growth.,D Chen 2023,2023,1 gene,Chen-2023-A lipid droplet-associated protein N,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22208,PHI:124288,UniProt,G4N4M5,GenBank,EHA52040,,,70-15,Nem1 (MGG_06001),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. E9,,,leaf,lipid droplet-associated protein,,,cAMP-PKA signaling pathway,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);rapamycin;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;rapamycin: CHEBI:9168; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,37581021,PubMed,10.1007/s42994-023-00098-5,aBIOTECH. 2023 Feb 18;4(2):108-123,chenxiaolin@mail.hzau.edu.cn,The Δnem1 mutant was nearly loss of virulence to host plants due to defects in appressorial penetration and invasive growth.,D Chen 2023,2023,1 gene,Chen-2023-A lipid droplet-associated protein N,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22209,PHI:124288,UniProt,G4N4M5,GenBank,EHA52040,,,70-15,Nem1 (MGG_06001),chromosome 3,serine was mutated to alanine (S303A) in Nem1,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,lipid droplet-associated protein,,,cAMP-PKA signaling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene mutation,,,NN,37581021,PubMed,10.1007/s42994-023-00098-5,aBIOTECH. 2023 Feb 18;4(2):108-123,chenxiaolin@mail.hzau.edu.cn,Δnem1/NEM1S303A was reduced of virulence to host plant.,D Chen 2023,2023,1 gene,Chen-2023-A lipid droplet-associated protein N,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22210,PHI:124289,UniProt,J4VS77,GenBank,EJP61460,,,ARSEF 2860,SdhC1 (EJP61460),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,succinate dehydrogenase subunit C,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,hydrogen peroxide (H2O2);menadione;sucrose;glycerol;glucose;ammonium chloride,hydrogen peroxide (H2O2): CHEBI:16240; ;menadione: CHEBI:28869; ;sucrose: CHEBI:17992; ;glycerol: CHEBI:17754; ;glucose: CHEBI:17234,,,,,gene deletion: full ; gene complementation,,,NN,35972281,PubMed,10.1128/spectrum.02891-22,Microbiol Spectr. 2022 Oct 26;10(5):e0289122.,yingsh@zju.edu.cn,Disruption of BbSdhC1 significantly attenuated fungal virulence against the insect hosts.,J L Ding 2022,2022,1 gene,Ding-2022-Succinate Dehydrogenase Subunit C Co,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22211,PHI:124290,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,Pgp3W234A,,,,,83560,Chlamydia muridarum,,,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,genital tract,plasmid-encoded protein,,,,reduced virulence,,,,,,,,,reduced,no,,,,,,,gene mutation,,,NN,37497542,PubMed,10.3389/fmicb.2023.1216372,Front Microbiol. 2023 Jul 11;14:1216372,liuyuanjun1980@126.com,Pgp3W234A produced significantly smaller plaques than the pGFP intact control.,Y Huang 2023,2023,1 gene,Huang-2023-Tryptophan residue of plasmid-encod,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22212,PHI:124290,UniProt,Q46439,GenBank,CAA55376,,,MoPn; NiggII,Pgp3,,Pgp3Y197A,,,,,83560,Chlamydia muridarum,,,hydrosalpinx,rodents,10090,Mus musculus (related: house mouse),C3H/HeJ,,,genital tract,plasmid-encoded protein,,,,reduced virulence,,,,,,,,,reduced,no,,,,,,,gene mutation,,,NN,37497542,PubMed,10.3389/fmicb.2023.1216372,Front Microbiol. 2023 Jul 11;14:1216372,liuyuanjun1980@126.com,Pgp3Y197A produced intermediate-sized plaques than control.,Y Huang 2023,2023,1 gene,Huang-2023-Tryptophan residue of plasmid-encod,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22213,PHI:124291,UniProt,G4MTF9,GenBank,EHA54710,,,70-15,JMJD6 (MGG_01543),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Lijiangxintuanheigu,,,leaf,nuclear protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full,,,NN,37550982,PubMed,10.5423/PPJ.OA.12.2022.0161,Plant Pathol J. 2023 Aug;39(4):361-373,wwxbua@163.com,Reduced virulence of the ΔMojmjd6 deletion mutants was seen on the leaves of rice seedlings.,L Zhang 2023,2023,1 gene,"Zhang-2023-MoJMJD6, a Nuclear Protein, Regulat",BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22214,PHI:124292,UniProt,G4ZAL2,,,,,,ZFPK1 (345221),,,,,,,67593,Phytophthora sojae,,P6497,stem rot (soybean); root rot (soybean),eudicots,3847,Glycine max (related: soybean),cv. Williams,,,hypocotyl,FYVE domain-containing protein kinase,,,,reduced virulence,,,,,smaller lesions,increased,reduced,reduced,,no,sorbitol;hydrogen peroxide (H2O2);KCl;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;KCl: CHEBI:32588; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,37504698,PubMed,10.3390/jof9070709,J Fungi (Basel). 2023 Jun 28;9(7):709. doi: 10.3390/jof9070709,mjq2018@nwafu.edu.cn,Lesion length produced by PsZFPK1-knockout transformants was significantly shorter than that produced by P6497.,B Ru 2023,2023,1 gene,Ru-2023-A Novel FYVE Domain-Containing Protein,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22215,PHI:124293,UniProt,G8CVG9,GenBank,ADV72542,,,EPGS020401,Hfq,,,,,,,663,Vibrio alginolyticus,,HD-1,vibriosis,bivalves,106299,Azumapecten farreri (related: Farrer's scallop),,,,,RNA-binding protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37505340,PubMed,10.1007/s10529-023-03394-8,Biotechnol Lett. 2023 Oct;45(10):1279-1291,zhengfr@fio.org.cn,"LD50 value of the mutant strain was 2.372 × 104 CFU/mL, while the LD50 value of the wild-type strain was 1.567 × 103 CFU/ mL.",J Ma 2023,2023,1 gene,Ma-2023-A strain of Vibrio alginolyticus isola,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22216,PHI:124294,UniProt,A0A125YQM4,GenBank,EPR64462,,,GT1 (TGGT1_272460),gra72,,,,,,,5811,Toxoplasma gondii,,type II strain ME49,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,,hypothetical protein,,,secretory pathway,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37498952,PubMed,10.1371/journal.ppat.1011543,PLoS Pathog. 2023 Jul 27;19(7):e1011543,jsaeij@ucdavis.edu,Only one out of ten mice infected with wild-type parasites survived while eight out of ten mice infected with Δgra72 parasites survived throughout the duration of the experiment.,T C Paredes-Santos 2023,2023,1 gene,Paredes-Santos-2023-Genome-wide CRISPR screen,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22217,PHI:124295,,no data found,,,,,,EC12 (MDCF17236_17),,,,,,,690256,Colletotrichum fructicola,,1104-7,anthracnose,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf; fruit,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37596985,PubMed,10.1111/pbi.14166,Plant Biotechnol J. 2023 Aug 19,xiaofeiliang@ nwsuaf.edu.cn,Lesions incurred by ΔCfEC12-5 and ΔCfEC12-7 were obviously decreased compared to WT and ΔCfEC12-5-C strains at 60 hpi.,S Shang 2023,2023,1 gene,Shang-2023-A fungal CFEM-containing effector t,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22218,PHI:124295,,no data found,,,,,,EC12 (MDCF17236_17),,EC12ΔSP,,,,,690256,Colletotrichum fructicola,,1104-7,anthracnose,eudicots,3750,Malus domestica (related: apple),cv. Gala,,,leaf; fruit,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37596985,PubMed,10.1111/pbi.14166,Plant Biotechnol J. 2023 Aug 19,xiaofeiliang@ nwsuaf.edu.cn,"ΔCfEC12/CfEC12ΔSP transformant was defective in virulence, similar to that of the ΔCfEC12.",S Shang 2023,2023,1 gene,Shang-2023-A fungal CFEM-containing effector t,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22219,PHI:124296,UniProt,A0A0H2ZLY2,GenBank,ABJ53895,,,D39,aqpC (SPD_1320),,,,,,,1313,Streptococcus pneumoniae,171101,R6,pneumococcal pneumonia,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,lung,aquaporin,,,,reduced virulence,,,,,,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,34399618,PubMed,10.1128/mBio.01309-21,mBio. 2021 Aug 31;12(4):e0130921,tonghuichun@im.ac.cn,"Pn-aqpC deletion significantly enhanced mouse survival to 78%, compared with 22% and 43% survival rates in the wild-type- and Pn-aqpC-com-infected groups.",Q Hu 2021,2021,1 gene,Hu-2021-A Novel Aquaporin Subfamily Imports Ox,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22220,PHI:124297,UniProt,D0CEI4,,,,,,TrmB (OB946_12575),,,,,,,470,Acinetobacter baumannii,,ARC6851,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung; kidney,tRNA methyltransferase,,,,reduced virulence,,,,,,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37589464,PubMed,10.1128/mbio.01416-23,mBio. 2023 Aug 17:e0141623,mariofeldman@wustl.edu,"ΔtrmB mutant had a significant reduction (>10,000-fold) in recovered CFU as compared to the wild-type and complemented ARC6851 strains in all tested organs.",J C McGuffey 2023,2023,1 gene,McGuffey-2023-The tRNA methyltransferase TrmB,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22221,PHI:124297,UniProt,D0CEI4,GenBank,AKA32444,,,AB5075-UW,TrmB (ACX61_12415),,,,,,,470,Acinetobacter baumannii,,Ab04,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,spleen; lung; kidney,tRNA methyltransferase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37589464,PubMed,10.1128/mbio.01416-23,mBio. 2023 Aug 17:e0141623,mariofeldman@wustl.edu,Ab04 ΔtrmB (ACX61_12415) virulence is not attenuated in our murine model,J C McGuffey 2023,2023,1 gene,McGuffey-2023-The tRNA methyltransferase TrmB,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22222,PHI:124298,UniProt,A0A0F3WF96,GenBank,KAA1351064,,,EcFF133,irp2,,,,,,,562,Escherichia coli,,ZB1,neonatal meningitis,rodents,10090,Mus musculus (related: house mouse),,,,spleen; kidney; liver,yersiniabactin,,,NLRP3/caspase-1/GSDMD pathway,reduced virulence,,,,,low organ damage,,,,,no,,,,,,,gene deletion: full,,,NN,37511208,PubMed,10.3390/ijms241411451,Int J Mol Sci. 2023 Jul 14;24(14):11451,2021005@ynau.edu.cn,"Ybt-expressing ZB-1 caused significant organ damage, while the damage was reduced in mice infected with the ZB-1Δirp2 strain.",H Wang 2023,2023,1 gene,Wang-2023-Yersiniabactin-Producing E. coli Ind,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22223,PHI:124299,UniProt,Q8PLL9,GenBank,AAM36640,,,306,xylA1 (XAC1776),,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,159033,Citrus x aurantiifolia (related: lime),cv. Mexican,,,leaf,putative XI ORFs,,,,increased virulence (hypervirulence),,,,,larger necrotic area,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37511250,PubMed,10.3390/ijms241411491,Int J Mol Sci. 2023 Jul 15;24(14):11491,marinovo@ufscar.br,In XccΔxylA1 mutant the symptoms were more severe and produced a larger necrotic area when compared to the wild type.,A V Alexandrino 2023,2023,2 genes,Alexandrino-2023-Xylose Isomerase Depletion En,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22224,PHI:124300,UniProt,Q8PEW5,GenBank,AAM39060,,,306,xylA2 (XAC4225),,,,,,,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,159033,Citrus x aurantiifolia (related: lime),cv. Mexican,,,leaf,putative XI ORFs,,,,increased virulence (hypervirulence),,,,,larger necrotic area,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37511250,PubMed,10.3390/ijms241411491,Int J Mol Sci. 2023 Jul 15;24(14):11491,marinovo@ufscar.br,In XccΔxylA2 mutant the symptoms were more severe and produced a larger necrotic area when compared to the wild type.,A V Alexandrino 2023,2023,2 genes,Alexandrino-2023-Xylose Isomerase Depletion En,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22225,PHI:124299,UniProt,Q8PLL9,GenBank,AAM36640,,,306,xylA1 (XAC1776),,,,,,PHI:124300,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,159033,Citrus x aurantiifolia (related: lime),cv. Mexican,,,leaf,putative XI ORFs,,,,increased virulence (hypervirulence),,,,,larger necrotic area,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37511250,PubMed,10.3390/ijms241411491,Int J Mol Sci. 2023 Jul 15;24(14):11491,marinovo@ufscar.br,In XccΔxylA1ΔxylA2 double mutant the symptoms were more severe and produced a larger necrotic area when compared to the wild type.,A V Alexandrino 2023,2023,2 genes,Alexandrino-2023-Xylose Isomerase Depletion En,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22226,PHI:124300,UniProt,Q8PEW5,GenBank,AAM39060,,,306,xylA2 (XAC4225),,,,,,PHI:124299,346,Xanthomonas citri,1203463,subsp. citri strain 306,canker (Citrus),eudicots,159033,Citrus x aurantiifolia (related: lime),cv. Mexican,,,leaf,putative XI ORFs,,,,increased virulence (hypervirulence),,,,,larger necrotic area,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37511250,PubMed,10.3390/ijms241411491,Int J Mol Sci. 2023 Jul 15;24(14):11491,marinovo@ufscar.br,In XccΔxylA2 mutant the symptoms were more severe and produced a larger necrotic area when compared to the wild type.,A V Alexandrino 2023,2023,2 genes,Alexandrino-2023-Xylose Isomerase Depletion En,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22227,PHI:124301,UniProt,Q9UV71,GenBank,AAF21993,,,ATCC 10231,AOX2,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,alternative oxidase,,,cytochrome pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37500616,PubMed,10.1038/s41467-023-40209-w,Nat Commun. 2023 Jul 27;14(1):4528,suzanne.noble@ucsf.edu,The aox2-deletion strain was significantly less virulent than the parental strain.,Z Liu 2023,2023,1 gene,Liu-2023-Multifactor transcriptional control o,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22228,PHI:124301,UniProt,Q9UV71,GenBank,AAF21993,,,ATCC 10231,AOX2,,mutated GTCA motif,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney; liver; spleen; brain,alternative oxidase,,,cytochrome pathway,reduced virulence,,,,,,,,,,no,,,,,,,gene mutation,,,NN,37500616,PubMed,10.1038/s41467-023-40209-w,Nat Commun. 2023 Jul 27;14(1):4528,suzanne.noble@ucsf.edu,Mutated GTCA motifs or deleted pAOX2 −1278 to −1000 did not restore virulence.,Z Liu 2023,2023,1 gene,Liu-2023-Multifactor transcriptional control o,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22229,PHI:124302,UniProt,A0A509ARH9,GenBank,VUC58319,,,ANKA,MAP1 (PBANKA_1425900),chromosome 14,,,,,,5821,Plasmodium berghei,5823,ANKA,malaria,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,uncharacterized protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37563696,PubMed,10.1186/s13071-023-05896-w,Parasit Vectors. 2023 Aug 10;16(1):277,qijunchen759@syau.edu.cn,The PbMAP1-knockout parasite exhibited reduced pathogenicity.,J Gao 2023,2023,1 gene,Gao-2023-A heparin-binding protein of Plasmodi,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22230,PHI:124303,UniProt,Q2FIP8,GenBank,ABD20928,,,USA300_FPR3757,pepT1 (SAUSA300_0727),,,,,,,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,brain; heart; lung; kidney; spleen; liver,M20B family peptidases,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,37538308,PubMed,10.3389/fcimb.2023.1176769,Front Cell Infect Microbiol. 2023 Jul 19;13:1176769,shaw@usf.edu,In pepT1 one mouse died during the 7 day of infection and decrease in bacterial fitness compared by the wild type.,N J Torres 2023,2023,2 genes,Torres-2023-The identification of two M20B fam,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22231,PHI:124304,UniProt,A0A0H2XFJ9,GenBank,ABD20395,,,USA300_FPR3757,pepT2 (SAUSA300_1460),,,,,,,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,brain; heart; lung; kidney; spleen; liver,M20B family peptidases,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,37538308,PubMed,10.3389/fcimb.2023.1176769,Front Cell Infect Microbiol. 2023 Jul 19;13:1176769,shaw@usf.edu,All the mice in pepT2 survived and displayed a decreased in bacterial fitness compared by the wild type.,N J Torres 2023,2023,2 genes,Torres-2023-The identification of two M20B fam,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22232,PHI:124303,UniProt,Q2FIP8,GenBank,ABD20928,,,USA300_FPR3757,pepT1 (SAUSA300_0727),,,,,,PHI:124304,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,brain; heart; lung; kidney; spleen; liver,M20B family peptidases,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,37538308,PubMed,10.3389/fcimb.2023.1176769,Front Cell Infect Microbiol. 2023 Jul 19;13:1176769,shaw@usf.edu,All the mice in pepT1/pepT2 survived and displayed a decreased in bacterial fitness compared by the wild type.,N J Torres 2023,2023,2 genes,Torres-2023-The identification of two M20B fam,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22233,PHI:124304,UniProt,A0A0H2XFJ9,GenBank,ABD20395,,,USA300_FPR3757,pepT2 (SAUSA300_1460),,,,,,PHI:124303,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),,,,brain; heart; lung; kidney; spleen; liver,M20B family peptidases,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,37538308,PubMed,10.3389/fcimb.2023.1176769,Front Cell Infect Microbiol. 2023 Jul 19;13:1176769,shaw@usf.edu,All the mice in pepT1/pepT2 survived and displayed a decreased in bacterial fitness compared by the wild type.,N J Torres 2023,2023,2 genes,Torres-2023-The identification of two M20B fam,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22234,PHI:124303,UniProt,Q2FIP8,GenBank,ABD20928,,,USA300_FPR3757,pepT1 (SAUSA300_0727),,,,,,,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,M20B family peptidases,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,37538308,PubMed,10.3389/fcimb.2023.1176769,Front Cell Infect Microbiol. 2023 Jul 19;13:1176769,shaw@usf.edu,In human blood survival assay we identified mutation PepT1 had markedly decreased survival compared to the parent.,N J Torres 2023,2023,2 genes,Torres-2023-The identification of two M20B fam,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22235,PHI:124304,UniProt,A0A0H2XFJ9,GenBank,ABD20395,,,USA300_FPR3757,pepT2 (SAUSA300_1460),,,,,,,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,M20B family peptidases,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,37538308,PubMed,10.3389/fcimb.2023.1176769,Front Cell Infect Microbiol. 2023 Jul 19;13:1176769,shaw@usf.edu,In human blood survival assay we identified mutation PepT2 had markedly decreased survival compared to the parent.,N J Torres 2023,2023,2 genes,Torres-2023-The identification of two M20B fam,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22236,PHI:124303,UniProt,Q2FIP8,GenBank,ABD20928,,,USA300_FPR3757,pepT1 (SAUSA300_0727),,,,,,PHI:124304,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,M20B family peptidases,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,37538308,PubMed,10.3389/fcimb.2023.1176769,Front Cell Infect Microbiol. 2023 Jul 19;13:1176769,shaw@usf.edu,In human blood survival assay we identified double mutation PepT1/PepT2 had markedly decreased survival compared to the parent.,N J Torres 2023,2023,2 genes,Torres-2023-The identification of two M20B fam,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22237,PHI:124304,UniProt,A0A0H2XFJ9,GenBank,ABD20395,,,USA300_FPR3757,pepT2 (SAUSA300_1460),,,,,,PHI:124303,1280,Staphylococcus aureus,,USA300 JE2,skin infection; food poisoning; respiratory disease,primates,9606,Homo sapiens (related: human),,,,blood,M20B family peptidases,,,,increased virulence (hypervirulence),,,,,,,,wild type,,no,,,,,,,gene mutation; gene complementation,,,NN,37538308,PubMed,10.3389/fcimb.2023.1176769,Front Cell Infect Microbiol. 2023 Jul 19;13:1176769,shaw@usf.edu,In human blood survival assay we identified double mutation PepT1/PepT2 had markedly decreased survival compared to the parent.,N J Torres 2023,2023,2 genes,Torres-2023-The identification of two M20B fam,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22238,PHI:124305,UniProt,Q888W0,,,,,,HopAI1,,,,,,,317,Pseudomonas syringae,,,,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,effector protein,,,MAPK pathway,effector (plant avirulence determinant),,,,,low disease severity,,,,,no,,,,,,,heterologous expression; altered gene expression / gene regulation:,,,NN,37581020,PubMed,10.1007/s42994-023-00102-y,aBIOTECH. 2023 May 2;4(2):97-107,zhangjie@im.ac.cn,Disease index analyses indicated reduced pathogenicity of the HopAI1-expressing strain relative to the WT strain. Note: HopAI1 is a Ps gene being expressed in Vd.,Z Ye 2023,2023,4 genes,Ye-2023-A complete MAP kinase cascade controls,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22239,PHI:124306,UniProt,G2XH29,GenBank,EGY19127,,,VdLs.17,Kss1 (VDAG_09461),chromosome 7,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,putative MAPK gene,,,MAPK pathway,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37581020,PubMed,10.1007/s42994-023-00102-y,aBIOTECH. 2023 May 2;4(2):97-107,zhangjie@im.ac.cn,The VdΔkss1 mutant displayed much less severe disease symptoms than the WT strain.,Z Ye 2023,2023,4 genes,Ye-2023-A complete MAP kinase cascade controls,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22240,PHI:124307,UniProt,G2XEP1,GenBank,EGY18292,,,VdLs.17,Ste7 (VDAG_08626),chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,putative MAPK gene,,,MAPK pathway,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37581020,PubMed,10.1007/s42994-023-00102-y,aBIOTECH. 2023 May 2;4(2):97-107,zhangjie@im.ac.cn,Reduced pathogenicity was observed in both the VdΔste7,Z Ye 2023,2023,4 genes,Ye-2023-A complete MAP kinase cascade controls,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22241,PHI:124308,UniProt,G2X6P0,GenBank,EGY14658,,,VdLs.17,Ste11 (VDAG_05822),chromosome 4,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),cv. Xinluzao 16,,,seedling,putative MAPK gene,,,MAPK pathway,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37581020,PubMed,10.1007/s42994-023-00102-y,aBIOTECH. 2023 May 2;4(2):97-107,zhangjie@im.ac.cn,Reduced pathogenicity was observed in both the VdΔste11,Z Ye 2023,2023,4 genes,Ye-2023-A complete MAP kinase cascade controls,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22242,PHI:124309,UniProt,Q8CX10,GenBank,AAM99915,,,2603V/R,essC (SAG1033),,,,,,,1311,Streptococcus agalactiae,,118659,neonatal pneumonia; neonatal meningitis; bovine mastitis; meningoencephalitis (fish),moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,membrane-bound ATPase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37545859,PubMed,10.3389/fcimb.2023.1168530,Front Cell Infect Microbiol. 2023 Jul 21;13:1168530,yasminm@wmc.gov.il,Larval mortality in the mutant inoculated group was significantly reduced (p = 0.03) compared to the WT strain.,Y Schindler 2023,2023,1 gene,Schindler-2023-Type VII secretion system and i,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22243,PHI:124310,UniProt,A0A0L0W0T8,,,,,,CAP1 (PSTG_01738),,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,yellow rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,"cysteine-rich secretory proteins (C), antigen 5 (A), and pathogenesis-related 1 proteins (P)",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37504723,PubMed,10.3390/jof9070734,J Fungi (Basel). 2023 Jul 7;9(7):734,kangzs@nwsuaf.edu.cn,PsCAP1 contribute significantly reduced Pst infection in wheat compared to wild type.,M Zhao 2023,2023,6 genes,Zhao-2023-Identification and Functional Analys,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22244,PHI:124311,UniProt,A0A0L0W1I0,,,,,,CAP2 (PSTG_01739),,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,yellow rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,"cysteine-rich secretory proteins (C), antigen 5 (A), and pathogenesis-related 1 proteins (P)",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37504723,PubMed,10.3390/jof9070734,J Fungi (Basel). 2023 Jul 7;9(7):734,kangzs@nwsuaf.edu.cn,PsCAP2 contribute same Pst infection in wheat compared to wild type.,M Zhao 2023,2023,6 genes,Zhao-2023-Identification and Functional Analys,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22245,PHI:124312,UniProt,A0A0L0VM33,,,,,,CAP3 (PSTG_06516),,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,yellow rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,"cysteine-rich secretory proteins (C), antigen 5 (A), and pathogenesis-related 1 proteins (P)",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37504723,PubMed,10.3390/jof9070734,J Fungi (Basel). 2023 Jul 7;9(7):734,kangzs@nwsuaf.edu.cn,PsCAP3 contribute same Pst infection in wheat compared to wild type.,M Zhao 2023,2023,6 genes,Zhao-2023-Identification and Functional Analys,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22246,PHI:124313,UniProt,A0A0L0V8P0,,,,,,CAP4 (PSTG_11017),,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,yellow rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,"cysteine-rich secretory proteins (C), antigen 5 (A), and pathogenesis-related 1 proteins (P)",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37504723,PubMed,10.3390/jof9070734,J Fungi (Basel). 2023 Jul 7;9(7):734,kangzs@nwsuaf.edu.cn,PsCAP4 contribute significantly reduced Pst infection in wheat compared to wild type.,M Zhao 2023,2023,6 genes,Zhao-2023-Identification and Functional Analys,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22247,PHI:124314,UniProt,A0A0L0V1X2,,,,,,CAP5 (PSTG_13342),,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,yellow rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,"cysteine-rich secretory proteins (C), antigen 5 (A), and pathogenesis-related 1 proteins (P)",,,,reduced virulence,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37504723,PubMed,10.3390/jof9070734,J Fungi (Basel). 2023 Jul 7;9(7):734,kangzs@nwsuaf.edu.cn,PsCAP5 contribute significantly reduced Pst infection in wheat compared to wild type.,M Zhao 2023,2023,6 genes,Zhao-2023-Identification and Functional Analys,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22248,PHI:124315,UniProt,A0A0L0UUF3,,,,,,CAP6 (PSTG_15884),,,,,,,27350,Puccinia striiformis,931977,f. sp. tritici strain CYR32,yellow rust,monocots,4565,Triticum aestivum (related: bread wheat),cv. Suwon 11,,,leaf,"cysteine-rich secretory proteins (C), antigen 5 (A), and pathogenesis-related 1 proteins (P)",,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37504723,PubMed,10.3390/jof9070734,J Fungi (Basel). 2023 Jul 7;9(7):734,kangzs@nwsuaf.edu.cn,PsCAP6 contribute same Pst infection in wheat compared to wild type.,M Zhao 2023,2023,6 genes,Zhao-2023-Identification and Functional Analys,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22249,PHI:124316,UniProt,J4W7P1,GenBank,EJP66260,,,ARSEF 2860,Eng1 (BBA_04753),chromosome unknown,,,,,,176275,Beauveria bassiana,,Bb2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"endo-beta-1,3-glucanase",,,Toll receptor pathway,reduced virulence,,,,,,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37556475,PubMed,10.1371/journal.ppat.1011578,PLoS Pathog. 2023 Aug 9;19(8):e1011578,yjzhang@swu.edu.cn,"LT50 for the ΔBbEng1 strain = 147.3 ± 3.5 h, which was significantly higher (i.e., showed reduced virulence) as compared to the wild type and complemented strains.",H Wang 2023,2023,3 genes,Wang-2023-Insect fungal pathogens secrete a ce,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22250,PHI:124316,UniProt,J4W7P1,GenBank,EJP66260,,,ARSEF 2860,Eng1 (BBA_04753),chromosome unknown,,,,,,176275,Beauveria bassiana,,Bb2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"endo-beta-1,3-glucanase",,,Toll receptor pathway,increased virulence (hypervirulence),,,,,,increased,,reduced,reduced,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37556475,PubMed,10.1371/journal.ppat.1011578,PLoS Pathog. 2023 Aug 9;19(8):e1011578,yjzhang@swu.edu.cn,"LT50 for the BbEng1OE strain = 109.9 ± 1.2 h, which was significantly lower (i.e., showed increased virulence P < 0.01) as compared to the wild type and complemented strains.",H Wang 2023,2023,3 genes,Wang-2023-Insect fungal pathogens secrete a ce,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22251,PHI:124317,UniProt,E9DRC7,,,,,,Eng1,,,,,,,568076,Metarhizium robertsii,655844,ARSEF 23,,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"endo-beta-1,3-glucanase",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37556475,PubMed,10.1371/journal.ppat.1011578,PLoS Pathog. 2023 Aug 9;19(8):e1011578,yjzhang@swu.edu.cn,Significantly increased virulence is seen in MrEng1OE strain compared to the wild type parent. Proteome id (GCA_000187405.1),H Wang 2023,2023,3 genes,Wang-2023-Insect fungal pathogens secrete a ce,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22252,PHI:124318,UniProt,A0A014N184,,,,,,Eng1,,,,,,,92637,Metarhizium acridum,655827,CQMa 102,infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,"endo-beta-1,3-glucanase",,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37556475,PubMed,10.1371/journal.ppat.1011578,PLoS Pathog. 2023 Aug 9;19(8):e1011578,yjzhang@swu.edu.cn,Significantly increased virulence is seen in MaEng1OE strain compared to the wild type parent. Proteome id (GCA_000187425.2),H Wang 2023,2023,3 genes,Wang-2023-Insect fungal pathogens secrete a ce,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22253,PHI:124319,UniProt,G2WSS3,,,,,,FRQ (VDAG_JR2_Chr1g01960a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling; hypocotyl,frequency clock protein,,,,unaffected pathogenicity,,,,,wild type,reduced,,defective,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37504714,PubMed,10.3390/jof9070725,J Fungi (Basel). 2023 Jul 4;9(7):725,rhartin@gwdg.de,No significant difference between disease symptoms induced by strain with FRQ deletion compared with wildtype.,A Nagel 2023,2023,4 genes,Nagel-2023-The Frq-Frh Complex Light-Dependent,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22254,PHI:124320,,no data found,,,,,,FRH (VDAG_JR2_Chr4g00070aa),,Guanine to adenine at position 2481 leads to an arginine to histidine codon exchange (FRHR806H),,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling; hypocotyl,frq-interacting RNA helicase,,,,unaffected pathogenicity,,,,,wild type,reduced,,defective,,no,,,,,,,gene mutation; gene complementation,,,NN,37504714,PubMed,10.3390/jof9070725,J Fungi (Basel). 2023 Jul 4;9(7):725,rhartin@gwdg.de,No significant difference between disease symptoms induced by strain with FrhR806H aa exchange compared with wildtype.,A Nagel 2023,2023,4 genes,Nagel-2023-The Frq-Frh Complex Light-Dependent,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22255,PHI:124321,,no data found,,,,,,WC1 (VDAG_JR2_Chr2g01990a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling; hypocotyl,white collar 1,,,,unaffected pathogenicity,,,,,wild type,reduced,,defective,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37504714,PubMed,10.3390/jof9070725,J Fungi (Basel). 2023 Jul 4;9(7):725,rhartin@gwdg.de,No significant difference between disease symptoms induced by strain with WC1 deletion compared with wildtype.,A Nagel 2023,2023,4 genes,Nagel-2023-The Frq-Frh Complex Light-Dependent,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22256,PHI:124322,,no data found,,,,,,SFL1 (VDAG_JR2_Chr4g02790a),,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling; hypocotyl,transcription factor,,,,unaffected pathogenicity,,,,,wild type,reduced,,defective,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37504714,PubMed,10.3390/jof9070725,J Fungi (Basel). 2023 Jul 4;9(7):725,rhartin@gwdg.de,No significant difference between disease symptoms induced by strain with SFL1 deletion compared with wildtype.,A Nagel 2023,2023,4 genes,Nagel-2023-The Frq-Frh Complex Light-Dependent,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22257,PHI:124319,UniProt,G2WSS3,,,,,,FRQ (VDAG_JR2_Chr1g01960a),,,,,,PHI:124322,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling; hypocotyl,frequency clock protein,,,,reduced virulence,,,,,low disease severity,,,defective,,no,,,,,,,gene deletion: full,,,NN,37504714,PubMed,10.3390/jof9070725,J Fungi (Basel). 2023 Jul 4;9(7):725,rhartin@gwdg.de,"Plants treated with spores of the FRQ/SFL1 double-deletion strain were slightly, but significantly less diseased than wild-type infected plants.",A Nagel 2023,2023,4 genes,Nagel-2023-The Frq-Frh Complex Light-Dependent,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22258,PHI:124322,,no data found,,,,,,SFL1 (VDAG_JR2_Chr4g02790a),,,,,,PHI:124319,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Moneymaker,,,seedling; hypocotyl,transcription factor,,,,reduced virulence,,,,,low disease severity,,,defective,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37504714,PubMed,10.3390/jof9070725,J Fungi (Basel). 2023 Jul 4;9(7):725,rhartin@gwdg.de,"Plants treated with spores of the FRQ/SFL1 double-deletion strain were slightly, but significantly less diseased than wild-type infected plants.",A Nagel 2023,2023,4 genes,Nagel-2023-The Frq-Frh Complex Light-Dependent,BATCH_125A,2023-09-01,MC,,,,,,,,,,,,,
,,Record 22259,PHI:124323,UniProt,A0A2H0ZMI1,GenBank,PIS51845,,,B8441,ras1 (B9J08_003446),,,,,,,498019,Candida auris,,B8441,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,small GTPase,,,Ras/cAMP/PKA signaling pathway,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671881,PubMed,10.1128/spectrum.02152-23,Microbiol Spectr. 2023 Sep 6:e0215223.,ysbahn@yonsei.ac.kr,"The virulence of ras1Δ was similar to that of the wild-type strain, with mice inoculated with these strains dying mostly within 20–25 days of infection.",J S Kim 2023,2023,5 genes,Kim-2023-Deciphering the regulatory mechanisms,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22260,PHI:124324,UniProt,A0A2H0ZK79,GenBank,PIS51064,,,B8441,gpa2 (B9J08_002635),,,,,,,498019,Candida auris,,B8441,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,G-protein α subunit,,,Ras/cAMP/PKA signaling pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671881,PubMed,10.1128/spectrum.02152-23,Microbiol Spectr. 2023 Sep 6:e0215223.,ysbahn@yonsei.ac.kr,"The virulence of gpa2Δ was similar to that of the wild-type strain, with mice inoculated with these strains dying mostly within 20–25 days of infection.",J S Kim 2023,2023,5 genes,Kim-2023-Deciphering the regulatory mechanisms,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22261,PHI:124325,UniProt,A0A2H0ZWA1,GenBank,PIS54917,,,B8441,gpr1 (B9J08_002066),,,,,,,498019,Candida auris,,B8441,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,G-protein-coupled receptor,,,Ras/cAMP/PKA signaling pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671881,PubMed,10.1128/spectrum.02152-23,Microbiol Spectr. 2023 Sep 6:e0215223.,ysbahn@yonsei.ac.kr,"The virulence of gpr1Δ was similar to that of the wild-type strain, with mice inoculated with these strains dying mostly within 20–25 days of infection.",J S Kim 2023,2023,5 genes,Kim-2023-Deciphering the regulatory mechanisms,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22262,PHI:124326,UniProt,A0A2H0ZVW7,GenBank,PIS54769,,,B8441,pde1 (B9J08_002549),,,,,,,498019,Candida auris,,B8441,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,phosphodiesterase,,,Ras/cAMP/PKA signaling pathway,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671881,PubMed,10.1128/spectrum.02152-23,Microbiol Spectr. 2023 Sep 6:e0215223.,ysbahn@yonsei.ac.kr,"The virulence of pde1Δ was similar to that of the wild-type strain, with mice inoculated with these strains dying mostly within 20–25 days of infection.",J S Kim 2023,2023,5 genes,Kim-2023-Deciphering the regulatory mechanisms,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22263,PHI:124327,UniProt,A0A2H0ZSM8,GenBank,PIS51668,,,B8441,pde2 (B9J08_003265),,,,,,,498019,Candida auris,,B8441,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,phosphodiesterase,,,Ras/cAMP/PKA signaling pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671881,PubMed,10.1128/spectrum.02152-23,Microbiol Spectr. 2023 Sep 6:e0215223.,ysbahn@yonsei.ac.kr,"pde2Δ exhibited reduced virulence compared to the wild type, with mice inoculated with these mutants surviving up to 16 days longer than those inoculated with the wild type.",J S Kim 2023,2023,5 genes,Kim-2023-Deciphering the regulatory mechanisms,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22264,PHI:124326,UniProt,A0A2H0ZVW7,GenBank,PIS54769,,,B8441,pde1 (B9J08_002549),,,,,,PHI:124327,498019,Candida auris,,B8441,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,phosphodiesterase,,,Ras/cAMP/PKA signaling pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671881,PubMed,10.1128/spectrum.02152-23,Microbiol Spectr. 2023 Sep 6:e0215223.,ysbahn@yonsei.ac.kr,"pde1Δ pde2Δ exhibited reduced virulence compared to the wild type, with mice inoculated with these mutants surviving up to 16 days longer than those inoculated with the wild type.",J S Kim 2023,2023,5 genes,Kim-2023-Deciphering the regulatory mechanisms,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22265,PHI:124327,UniProt,A0A2H0ZSM8,GenBank,PIS51668,,,B8441,pde2 (B9J08_003265),,,,,,PHI:124326,498019,Candida auris,,B8441,infection,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,,phosphodiesterase,,,Ras/cAMP/PKA signaling pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671881,PubMed,10.1128/spectrum.02152-23,Microbiol Spectr. 2023 Sep 6:e0215223.,ysbahn@yonsei.ac.kr,"pde1Δ pde2Δ exhibited reduced virulence compared to the wild type, with mice inoculated with these mutants surviving up to 16 days longer than those inoculated with the wild type.",J S Kim 2023,2023,5 genes,Kim-2023-Deciphering the regulatory mechanisms,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22266,PHI:124328,UniProt,A0A8E5HR16,,,,,,Uv1809,,,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,spikelet,secreted protein,,,,reduced virulence,,,,,low disease severity,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37715970,PubMed,10.1111/pbi.14174,Plant Biotechnol J. 2023 Sep 16. doi: 10.1111/pbi.14174. Online ahead of print,qtxu@mail.hzau.edu,Virulence of ΔUv1809 mutants was significantly reduced compared to the wild-type strain HWD-2 and the complementation strain.,X Chen 2023,2023,1 gene,Chen-2023-Ustilaginoidea virens-secreted effec,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22267,PHI:124328,UniProt,A0A8E5HR16,,,,,,Uv1809,,Uv1809ΔSP,,,,,1159556,Ustilaginoidea virens,,HWD-2,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Wanxian 98,,,spikelet,secreted protein,,,,reduced virulence,,,,,low disease severity,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37715970,PubMed,10.1111/pbi.14174,Plant Biotechnol J. 2023 Sep 16. doi: 10.1111/pbi.14174. Online ahead of print,qtxu@mail.hzau.edu,CΔUv1809DSP-1 transformant strain showed a similar virulence to that of the ΔUv1809-1 mutant and exhibited significantly reduced virulence compared to the wild-type strain HWD-2 and the complementation strain.,X Chen 2023,2023,1 gene,Chen-2023-Ustilaginoidea virens-secreted effec,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22268,PHI:124329,UniProt,Q2YPX1,GenBank,CAJ11088,,,2308,ClpP,chromosome I,,,,,,235,Brucella abortus,1310173,2308,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line; BALB/c,,,macrophage; spleen; liver; kidney,protease,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37612737,PubMed,10.1186/s13567-023-01200-x,Vet Res. 2023 Aug 23;54(1):68.,dingjiabo@126.com,Deletion of clpP significantly affected Brucella virulence in macrophage and mouse infection models.,D Sun 2023,2023,1 gene,Sun-2023-ClpP protease modulates bacterial gro,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22269,PHI:124330,UniProt,I1RK80,,,,,,HGG4 (FGSG_04274),,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,elongator complex protein 4,,,ubiquitin-proteasome pathway,reduced virulence,,,,,low disease severity,increased,wild type,reduced ; defective,,no,hydrogen peroxide (H2O2);hydroxyurea;bleomycin;camptothecin,hydrogen peroxide (H2O2): CHEBI:16240; ;hydroxyurea: CHEBI:44423; ;bleomycin: CHEBI:22907; ;camptothecin: CHEBI:27656,,,,,gene deletion: full ; gene complementation,,,NN,37671872,PubMed,10.1128/spectrum.01485-23,Microbiol Spectr. 2023 Sep 6:e0148523.,yseo2011@pusan.ac.kr,Δfghgg4 showed markedly reduced virulence compared to wild type.,J Park 2023,2023,3 genes,Park-2023-A combined transcriptomic and physio,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22270,PHI:124331,UniProt,I1RUR0,,,,,,HGG10 (FGSG_07962),,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,DNA repair and recombination protein RAD54 and RAD54-like protein,,,ubiquitin-proteasome pathway,reduced virulence,,,,,low disease severity,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2);hydroxyurea;bleomycin;camptothecin,hydrogen peroxide (H2O2): CHEBI:16240; ;hydroxyurea: CHEBI:44423; ;bleomycin: CHEBI:22907; ;camptothecin: CHEBI:27656,,,,,gene deletion: full ; gene complementation,,,NN,37671872,PubMed,10.1128/spectrum.01485-23,Microbiol Spectr. 2023 Sep 6:e0148523.,yseo2011@pusan.ac.kr,Δfghgg10 showed markedly reduced virulence compared to wild type.,J Park 2023,2023,3 genes,Park-2023-A combined transcriptomic and physio,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22271,PHI:124332,UniProt,I1S0D5,,,,,,HGG13 (FGSG_10158),,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Eunpamil,,,spike,DNA repair and recombination protein RAD52,,,ubiquitin-proteasome pathway,reduced virulence,,,,,low disease severity,reduced,reduced,reduced ; defective,,no,hydrogen peroxide (H2O2);hydroxyurea;bleomycin;camptothecin,hydrogen peroxide (H2O2): CHEBI:16240; ;hydroxyurea: CHEBI:44423; ;bleomycin: CHEBI:22907; ;camptothecin: CHEBI:27656,,,,,gene deletion: full ; gene complementation,,,NN,37671872,PubMed,10.1128/spectrum.01485-23,Microbiol Spectr. 2023 Sep 6:e0148523.,yseo2011@pusan.ac.kr,Δfghgg13 showed markedly reduced virulence compared to wild type.,J Park 2023,2023,3 genes,Park-2023-A combined transcriptomic and physio,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22272,PHI:124333,UniProt,A0A384JPG6,GenBank,ATZ52244,,,B05.10,pdeR (BCIN_08g00160),BCIN08,,,,,,40559,Botrytis cinerea,,NY76,grey mold,eudicots,4081,Solanum lycopersicum (related: tomato),cv. Seokwang,,,leaf,Zn(II)2Cys6 zinc finger transcription factor,,,,reduced virulence,,,yes,,,,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32786857,PubMed,10.1021/acs.jafc.0c02420,J Agric Food Chem. 2020 Aug 26;68(34):9171-9179.,swhan@cau.ac.kr,"When the ΔpdeR strain was inoculated onto pepper plant, the ΔpdeR strain did not cause expansion of the disease lesions from the infection sites, which grew on the surface without any penetration.",J W Han 2020,2020,1 gene,Han-2020-Transcription Factor PdeR Is Involved,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22273,PHI:124333,UniProt,A0A384JPG6,GenBank,ATZ52244,,,B05.10,pdeR (BCIN_08g00160),BCIN08,,,,,,40559,Botrytis cinerea,,NY76,grey mold,eudicots,4072,Capsicum annuum (no common name found),cv. Bugang,,,leaf,Zn(II)2Cys6 zinc finger transcription factor,,,,reduced virulence,,,yes,,,,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32786857,PubMed,10.1021/acs.jafc.0c02420,J Agric Food Chem. 2020 Aug 26;68(34):9171-9179.,swhan@cau.ac.kr,"When the ΔpdeR strain was inoculated onto pepper plant, the ΔpdeR strain did not cause expansion of the disease lesions from the infection sites, which grew on the surface without any penetration.",J W Han 2020,2020,1 gene,Han-2020-Transcription Factor PdeR Is Involved,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22274,PHI:124334,UniProt,P16153,GenBank,CAA43300,,,VPI 10463,TcdE,,,,,,,1496,Clostridioides difficile,,UK1,nosocomial diarrhea,rodents,10090,Mus musculus (related: house mouse),,,,colon,holin-like protein,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37745472,PubMed,10.1101/2023.09.16.558055,bioRxiv. 2023 Sep 16:2023.09.16.558055.,,All mice infected with the isogenic ΔtcdE strain survived infection and with no loss of weight.,N V DiBenedetto 2023,2023,1 gene,DiBenedetto-2023-The TcdE holin drives toxin s,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22275,PHI:124334,UniProt,P16153,GenBank,CAA43300,,,VPI 10463,TcdE,,,,,,,1496,Clostridioides difficile,,VPI10463,nosocomial diarrhea,rodents,10090,Mus musculus (related: house mouse),,,,colon,holin-like protein,,,,loss of pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37745472,PubMed,10.1101/2023.09.16.558055,bioRxiv. 2023 Sep 16:2023.09.16.558055.,,All mice infected with the isogenic ΔtcdE strain survived infection and with no loss of weight.,N V DiBenedetto 2023,2023,1 gene,DiBenedetto-2023-The TcdE holin drives toxin s,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22276,PHI:124335,UniProt,A0A0B8RFK3,GenBank,GAM94678,,,NIHS-28,FolD,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver,methylenetetrahydrofolate dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37695058,PubMed,10.1128/mbio.01074-23,mBio. 2023 Sep 11:e0107423.,portnoy@berkeley.edu,The ΔfolD mutant exhibited an organ-specific defect that presented as a 2-log10 virulence attenuation in the livers compared with WT and the complemented strain.,Y Feng 2023,2023,4 genes,Feng-2023-The major role of Listeria monocytog,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22277,PHI:124335,UniProt,A0A0B8RFK3,GenBank,GAM94678,,,NIHS-28,FolD,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,spleen,methylenetetrahydrofolate dehydrogenase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37695058,PubMed,10.1128/mbio.01074-23,mBio. 2023 Sep 11:e0107423.,portnoy@berkeley.edu,ΔfolD mutant showed no difference in colony-forming units (CFUs) in the spleens.,Y Feng 2023,2023,4 genes,Feng-2023-The major role of Listeria monocytog,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22278,PHI:124336,UniProt,A0A2Z5C1F5,GenBank,EAD1185849,,,FDA694493-72,Fhs,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,formyltetrahydrofolate synthetase,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37695058,PubMed,10.1128/mbio.01074-23,mBio. 2023 Sep 11:e0107423.,portnoy@berkeley.edu,The Δfhs mutant exhibited virulence attenuation in both livers and spleen compared with WT and the complemented strain.,Y Feng 2023,2023,4 genes,Feng-2023-The major role of Listeria monocytog,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22279,PHI:124335,UniProt,A0A0B8RFK3,GenBank,GAM94678,,,NIHS-28,FolD,,,,,,PHI:124336,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,methylenetetrahydrofolate dehydrogenase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37695058,PubMed,10.1128/mbio.01074-23,mBio. 2023 Sep 11:e0107423.,portnoy@berkeley.edu,"Mutants lacking both folD and fhs (Δfhs folD::Tn) were severely attenuated, with approximately 4-log10 fewer CFUs in infected livers compared with WT and a 1.5-log10 defect in the spleens",Y Feng 2023,2023,4 genes,Feng-2023-The major role of Listeria monocytog,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22280,PHI:124336,UniProt,A0A2Z5C1F5,GenBank,EAD1185849,,,FDA694493-72,Fhs,,,,,,PHI:124335,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,formyltetrahydrofolate synthetase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37695058,PubMed,10.1128/mbio.01074-23,mBio. 2023 Sep 11:e0107423.,portnoy@berkeley.edu,"Mutants lacking both folD and fhs (Δfhs folD::Tn) were severely attenuated, with approximately 4-log10 fewer CFUs in infected livers compared with WT and a 1.5-log10 defect in the spleens",Y Feng 2023,2023,4 genes,Feng-2023-The major role of Listeria monocytog,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22281,PHI:124337,UniProt,A0A0E1R3X2,GenBank,CCO62615,,,LL195,PurR,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,transcriptional repressor,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37695058,PubMed,10.1128/mbio.01074-23,mBio. 2023 Sep 11:e0107423.,portnoy@berkeley.edu,The ΔpurR mutant exhibited wild type virulence in both livers and spleen compared with WT and the complemented strain.,Y Feng 2023,2023,4 genes,Feng-2023-The major role of Listeria monocytog,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22282,PHI:124335,UniProt,A0A0B8RFK3,GenBank,GAM94678,,,NIHS-28,FolD,,,,,,PHI:124337,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,methylenetetrahydrofolate dehydrogenase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37695058,PubMed,10.1128/mbio.01074-23,mBio. 2023 Sep 11:e0107423.,portnoy@berkeley.edu,The ΔfolD ΔpurR mutant exhibited virulence attenuation in both livers and spleen compared with WT and the complemented strain.,Y Feng 2023,2023,4 genes,Feng-2023-The major role of Listeria monocytog,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22283,PHI:124337,UniProt,A0A0E1R3X2,GenBank,CCO62615,,,LL195,PurR,,,,,,PHI:124335,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,transcriptional repressor,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37695058,PubMed,10.1128/mbio.01074-23,mBio. 2023 Sep 11:e0107423.,portnoy@berkeley.edu,The ΔfolD ΔpurR mutant exhibited virulence attenuation in both livers and spleen compared with WT and the complemented strain.,Y Feng 2023,2023,4 genes,Feng-2023-The major role of Listeria monocytog,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22284,PHI:124338,UniProt,A0A6X4M8A1,GenBank,HAA9722771,,,HPB3501,fmt,,,,,,,1639,Listeria monocytogenes,393133,10403S,listeriosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,liver; spleen,methionyl-tRna formyltransferase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37695058,PubMed,10.1128/mbio.01074-23,mBio. 2023 Sep 11:e0107423.,portnoy@berkeley.edu,The Δfmt mutant exhibited virulence attenuation in both livers and spleen compared with WT and the complemented strain.,Y Feng 2023,2023,4 genes,Feng-2023-The major role of Listeria monocytog,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22285,PHI:124339,UniProt,I1RPG1,,,,,,HapX (FGSG_05930),,,,Ubp8; Grx4,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,coleoptile; spike,heme activator protein X,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37650633,PubMed,10.1093/nar/gkad708,Nucleic Acids Res. 2023 Aug 31:gkad708.,hubertus.haas@i-med.ac.at,Deletion of FgHapX or FgSreA resulted in significantly reduced virulence.,K Sun 2023,2023,3 genes,Sun-2023-HapX-mediated H2B deub1 and SreA-medi,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22286,PHI:124340,UniProt,I1RYV4,,,,,,SreA (FGSG_09565),,,,H2A.Z; Grx4,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,coleoptile; spike,siderophore transcription factor,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37650633,PubMed,10.1093/nar/gkad708,Nucleic Acids Res. 2023 Aug 31:gkad708.,hubertus.haas@i-med.ac.at,Deletion of FgHapX or FgSreA resulted in significantly reduced virulence.,K Sun 2023,2023,3 genes,Sun-2023-HapX-mediated H2B deub1 and SreA-medi,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22287,PHI:124339,UniProt,I1RPG1,,,,,,HapX (FGSG_05930),,,,Ubp8; Grx4,,PHI:124340,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,coleoptile; spike,heme activator protein X,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37650633,PubMed,10.1093/nar/gkad708,Nucleic Acids Res. 2023 Aug 31:gkad708.,hubertus.haas@i-med.ac.at,Double Deletion of FgHapX and FgSreA resulted in significantly reduced virulence.,K Sun 2023,2023,3 genes,Sun-2023-HapX-mediated H2B deub1 and SreA-medi,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22288,PHI:124340,UniProt,I1RYV4,,,,,,SreA (FGSG_09565),,,,H2A.Z; Grx4,,PHI:124339,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,coleoptile; spike,siderophore transcription factor,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37650633,PubMed,10.1093/nar/gkad708,Nucleic Acids Res. 2023 Aug 31:gkad708.,hubertus.haas@i-med.ac.at,Double Deletion of FgHapX and FgSreA resulted in significantly reduced virulence.,K Sun 2023,2023,3 genes,Sun-2023-HapX-mediated H2B deub1 and SreA-medi,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22289,PHI:124341,UniProt,I1RKZ4,,,,,,Grx4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),cv. Jimai 22,,,coleoptile; spike,monothiol glutaredoxin,,,,reduced virulence,,,,,smaller lesions,,,,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37650633,PubMed,10.1093/nar/gkad708,Nucleic Acids Res. 2023 Aug 31:gkad708.,hubertus.haas@i-med.ac.at,Deletion of FgGrx4 caused restricted scab symptoms only in inoculated wheat heads and coleoptiles.,K Sun 2023,2023,3 genes,Sun-2023-HapX-mediated H2B deub1 and SreA-medi,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22290,PHI:124342,,no data found,,,,,,B11,,,,,,,36809,Mycobacteroides abscessus,561007,ATCC 19977,pulmonary infection; cutaneo-mucous infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6NCrl,,,lung,small non-coding RNA,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37603560,PubMed,10.1371/journal.ppat.1011575,PLoS Pathog. 2023 Aug 21;19(8):e1011575.,sshell@wpi.edu,Larval survival was significantly reduced in the ΔB11-infected group.,M Bar-Oz 2023,2023,1 gene,Bar-Oz-2023-The small non-coding RNA B11 regul,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22291,PHI:124343,UniProt,A0A9P1K2G5,GenBank,CCQ38485,,,YE53/03,waaF,,,,,,,630,Yersinia enterocolitica,,ATCC 23715,yersiniosis,even-toed ungulates,9823,Sus scrofa (related: pig),IPEC-J2 cell line,,,intestinal epithelial cell,LPS heptosyltransferase II,,,signal transduction pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37728625,PubMed,10.1007/s00253-023-12785-w,Appl Microbiol Biotechnol. 2023 Sep 20.,xixianxie@tust.edu.cn,Deletion of the waaF gene markedly inhibits virulence and pathogenicity of Y. enterocolitica.,F Wu 2023,2023,1 gene,Wu-2023-The implication of viability and patho,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22292,PHI:124344,UniProt,B5XQD2,GenBank,ACI10637,,,342,ihfA,,,,,,,573,Klebsiella pneumoniae,,W14,pneumonia,primates,9606,Homo sapiens (related: human),,,,A-549 cell,integration host factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37732783,PubMed,10.1128/spectrum.01170-23,Microbiol Spectr. 2023 Sep 21:e0117023,yuanjing6216@163.com,"Compared to wild-type strain W14, ihfA deletion exhibited decreased cytotoxicity.",Z Fan 2023,2023,2 genes,Fan-2023-The role of integration host factor i,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22293,PHI:124345,UniProt,B5XY84,GenBank,ACI06745,,,342,ihfB,,,,,,,573,Klebsiella pneumoniae,,W14,pneumonia,primates,9606,Homo sapiens (related: human),,,,A-549 cell,integration host factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37732783,PubMed,10.1128/spectrum.01170-23,Microbiol Spectr. 2023 Sep 21:e0117023,yuanjing6216@163.com,"Compared to wild-type strain W14, ihfB deletion exhibited decreased cytotoxicity.",Z Fan 2023,2023,2 genes,Fan-2023-The role of integration host factor i,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22294,PHI:124346,,no data found,,,,,,ATPh,,,,ATP5; ATPb,,,5127,Fusarium fujikuroi,,A,bakanae,monocots,4530,Oryza sativa (related: rice),,,,seedling,ATP synthase,,,,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol;CaCl2;NaCl;MgCl2;ZnCl2;KCl;menadione;sodium dodecyl sulphate (SDS);fludioxonil;tebuconazole;prochloraz;phenamacril,sorbitol: CHEBI:30911; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;MgCl2: CHEBI:6636; ;ZnCl2: CHEBI:49976; ;KCl: CHEBI:32588; ;menadione: CHEBI:28869; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;fludioxonil: CHEBI:81763; ;tebuconazole: CHEBI:81781; ;prochloraz: CHEBI:8434; ;phenamacril: CAS:3336-69-4,,,,,gene deletion: full,,,NN,37686077,PubMed,10.3390/ijms241713273,Int J Mol Sci. 2023 Aug 26;24(17):13273.,houyiping@njau.edu.cn,Length of the rice shoot sheaths was significantly higher than that of the deletion mutant which was similar to control.,X Yang 2023,2023,3 genes,"Yang-2023-The ATP Synthase Subunits FfATPh, Ff",BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22295,PHI:124347,,no data found,,,,,,ATP5,,,,ATPh; ATPb,,,5127,Fusarium fujikuroi,,A,bakanae,monocots,4530,Oryza sativa (related: rice),,,,seedling,ATP synthase,,,,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol;CaCl2;NaCl;MgCl2;ZnCl2;KCl;menadione;sodium dodecyl sulphate (SDS);fludioxonil;tebuconazole;prochloraz;phenamacril,sorbitol: CHEBI:30911; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;MgCl2: CHEBI:6636; ;ZnCl2: CHEBI:49976; ;KCl: CHEBI:32588; ;menadione: CHEBI:28869; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;fludioxonil: CHEBI:81763; ;tebuconazole: CHEBI:81781; ;prochloraz: CHEBI:8434; ;phenamacril: CAS:3336-69-4,,,,,gene deletion: full,,,NN,37686077,PubMed,10.3390/ijms241713273,Int J Mol Sci. 2023 Aug 26;24(17):13273.,houyiping@njau.edu.cn,Length of the rice shoot sheaths was significantly higher than that of the deletion mutant which was similar to control.,X Yang 2023,2023,3 genes,"Yang-2023-The ATP Synthase Subunits FfATPh, Ff",BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22296,PHI:124348,,no data found,,,,,,ATPb,,,,ATPh; ATP5,,,5127,Fusarium fujikuroi,,A,bakanae,monocots,4530,Oryza sativa (related: rice),,,,seedling,ATP synthase,,,,reduced virulence,,,,,,reduced,,reduced,,no,sorbitol;CaCl2;NaCl;MgCl2;ZnCl2;KCl;menadione;sodium dodecyl sulphate (SDS);fludioxonil;tebuconazole;prochloraz;phenamacril,sorbitol: CHEBI:30911; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;MgCl2: CHEBI:6636; ;ZnCl2: CHEBI:49976; ;KCl: CHEBI:32588; ;menadione: CHEBI:28869; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;fludioxonil: CHEBI:81763; ;tebuconazole: CHEBI:81781; ;prochloraz: CHEBI:8434; ;phenamacril: CAS:3336-69-4,,,,,gene deletion: full,,,NN,37686077,PubMed,10.3390/ijms241713273,Int J Mol Sci. 2023 Aug 26;24(17):13273.,houyiping@njau.edu.cn,Length of the rice shoot sheaths was significantly higher than that of the deletion mutant which was similar to control.,X Yang 2023,2023,3 genes,"Yang-2023-The ATP Synthase Subunits FfATPh, Ff",BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22297,PHI:124349,UniProt,S0E8I3,GenBank,FFUJ_08745,,,,SdhB,,H248L,,,,,5127,Fusarium fujikuroi,,BY-2,bakanae,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,succinate dehydrogenase,,,,increased virulence (hypervirulence),,,,,larger lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,37729092,PubMed,10.1021/acs.jafc.3c03678,J Agric Food Chem. 2023 Oct 4;71(39):14330-14341.,chenyu66891@sina.com,Pathogenicity of the mutants was increased compared with that of the wild-type parental strain.,Y Liu 2023,2023,3 genes,Liu-2023-Study on Mechanisms of Resistance to,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22298,PHI:124349,UniProt,S0E8I3,GenBank,FFUJ_08745,,,,SdhB,,H248D,,,,,5127,Fusarium fujikuroi,,BY-2,bakanae,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,succinate dehydrogenase,,,,increased virulence (hypervirulence),,,,,larger lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,37729092,PubMed,10.1021/acs.jafc.3c03678,J Agric Food Chem. 2023 Oct 4;71(39):14330-14341.,chenyu66891@sina.com,,Y Liu 2023,2023,3 genes,Liu-2023-Study on Mechanisms of Resistance to,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22299,PHI:124349,UniProt,S0E8I3,GenBank,FFUJ_08745,,,,SdhB,,H248Y,,,,,5127,Fusarium fujikuroi,,BY-2,bakanae,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,succinate dehydrogenase,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,37729092,PubMed,10.1021/acs.jafc.3c03678,J Agric Food Chem. 2023 Oct 4;71(39):14330-14341.,chenyu66891@sina.com,,Y Liu 2023,2023,3 genes,Liu-2023-Study on Mechanisms of Resistance to,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22300,PHI:124349,UniProt,S0EEJ2,GenBank,FFUJ_12139,,,,SdhC2,,A83V,,,,,5127,Fusarium fujikuroi,,BY-2,bakanae,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,succinate dehydrogenase,,,,increased virulence (hypervirulence),,,,,larger lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,37729092,PubMed,10.1021/acs.jafc.3c03678,J Agric Food Chem. 2023 Oct 4;71(39):14330-14341.,chenyu66891@sina.com,Pathogenicity of the mutants was increased compared with that of the wild-type parental strain.,Y Liu 2023,2023,3 genes,Liu-2023-Study on Mechanisms of Resistance to,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22301,PHI:124349,UniProt,S0EEJ2,GenBank,FFUJ_12139,,,,SdhC2,,H144Y,,,,,5127,Fusarium fujikuroi,,BY-2,bakanae,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,succinate dehydrogenase,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene mutation,,,NN,37729092,PubMed,10.1021/acs.jafc.3c03678,J Agric Food Chem. 2023 Oct 4;71(39):14330-14341.,chenyu66891@sina.com,Pathogenicity of the mutants was same with that of the wild-type parental strain.,Y Liu 2023,2023,3 genes,Liu-2023-Study on Mechanisms of Resistance to,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22302,PHI:124350,UniProt,S0DPW6,GenBank,FFUJ_00494,,,,SdhD,,S106F,,,,,5127,Fusarium fujikuroi,,BY-2,bakanae,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,succinate dehydrogenase,,,,increased virulence (hypervirulence),,,,,larger lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,37729092,PubMed,10.1021/acs.jafc.3c03678,J Agric Food Chem. 2023 Oct 4;71(39):14330-14341.,chenyu66891@sina.com,Pathogenicity of the mutants was increased compared with that of the wild-type parental strain.,Y Liu 2023,2023,3 genes,Liu-2023-Study on Mechanisms of Resistance to,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22303,PHI:124350,UniProt,S0DPW6,GenBank,FFUJ_00494,,,,SdhD,,E166K,,,,,5127,Fusarium fujikuroi,,BY-2,bakanae,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,succinate dehydrogenase,,,,increased virulence (hypervirulence),,,,,larger lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,37729092,PubMed,10.1021/acs.jafc.3c03678,J Agric Food Chem. 2023 Oct 4;71(39):14330-14341.,chenyu66891@sina.com,Pathogenicity of the mutants was increased compared with that of the wild-type parental strain.,Y Liu 2023,2023,3 genes,Liu-2023-Study on Mechanisms of Resistance to,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22304,PHI:124349,UniProt,S0EEJ2,GenBank,FFUJ_12139,,,,SdhC2,,A83V,,,,,5127,Fusarium fujikuroi,,BY-6,bakanae,eudicots,4081,Solanum lycopersicum (related: tomato),,,,fruit,succinate dehydrogenase,,,,increased virulence (hypervirulence),,,,,larger lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,37729092,PubMed,10.1021/acs.jafc.3c03678,J Agric Food Chem. 2023 Oct 4;71(39):14330-14341.,chenyu66891@sina.com,Pathogenicity of the mutants was increased compared with that of the wild-type parental strain.,Y Liu 2023,2023,3 genes,Liu-2023-Study on Mechanisms of Resistance to,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22305,PHI:124351,UniProt,A7EQG7,GenBank,EDN91709,,,1980,Cak1 (XP_001590945.1),,,,,,,5180,Sclerotinia sclerotiorum,665079,,white mold,eudicots,3702,Arabidopsis thaliana (related: thale cress),ecotype Columbia-0,,,leaf,putative protein kinase,,,,reduced virulence,,,yes,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37628791,PubMed,10.3390/ijms241612610,Int J Mol Sci. 2023 Aug 9;24(16):12610.,xinli@msl.ubc.ca,"On wounded leaves, Sscak1 caused mild infection damage compared to the WT and complementation strain.",L Qin 2023,2023,1 gene,Qin-2023-SsCak1 Regulates Growth and Pathogeni,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22306,PHI:124351,UniProt,A7EQG7,GenBank,EDN91709,,,1980,Cak1 (XP_001590945.1),,,,,,,5180,Sclerotinia sclerotiorum,665079,,white mold,eudicots,4100,Nicotiana benthamiana (no common name found),Col-0,,,leaf,putative protein kinase,,,,reduced virulence,,,yes,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37628791,PubMed,10.3390/ijms241612610,Int J Mol Sci. 2023 Aug 9;24(16):12610.,xinli@msl.ubc.ca,"On wounded leaves, Sscak1 caused mild infection damage compared to the WT and complementation strain.",L Qin 2023,2023,1 gene,Qin-2023-SsCak1 Regulates Growth and Pathogeni,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22307,PHI:124352,UniProt,J4KLI2,GenBank,EJP62249,,,ARSEF 2860,Aorsin (BBA_08791),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,protease,,,,increased virulence (hypervirulence),,,,,high disease severity,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37602431,PubMed,10.1021/acs.jafc.3c02356,J Agric Food Chem. 2023 Aug 30;71(34):12757-12774.,rxj@ ahau.edu.cn,Overexpression of BbAorsin in B. bassiana ARSEF2860 enhanced virulence against Galleria mellonella larvae and inhibited F. graminearum growth.,B X Zhang 2023,2023,1 gene,Zhang-2023-Dual RNA Sequencing of Beauveria ba,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22308,PHI:124352,UniProt,J4KLI2,GenBank,EJP62249,,,ARSEF 2860,Aorsin (BBA_08791),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF 2860,white muscardine,moths,7108,Spodoptera frugiperda (related: Fall armyworm),,,,larva,protease,,,,increased virulence (hypervirulence),,,,,high disease severity,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,37602431,PubMed,10.1021/acs.jafc.3c02356,J Agric Food Chem. 2023 Aug 30;71(34):12757-12774.,rxj@ ahau.edu.cn,Overexpression of BbAorsin in B. bassiana ARSEF2860 enhanced virulence against FAW larvae and inhibited F. graminearum growth.,B X Zhang 2023,2023,1 gene,Zhang-2023-Dual RNA Sequencing of Beauveria ba,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22309,PHI:124353,UniProt,A0A1D8PHR5,GenBank,AOW27688,,,SC5314,pst1,chromosome 2,,,,,PHI:124354; PHI:124355; PHI:124356,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,flavodoxin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37732195,PubMed,10.1101/2023.09.05.556406,bioRxiv. 2023 Sep 6:2023.09.05.556406.,james.konopka@stonybrook.edu,Δ/Δ/Δ/Δ (pst1Δ/Δ 153 pst2Δ/Δ pst3Δ/Δ ycp4Δ/Δ) Mut strain had lower kidney fungal burden than the wild-type control strain.,R M Gandra 2023,2023,5 genes,Gandra-2023-The Candida albicans ?-crystallin,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22310,PHI:124354,UniProt,Q59Y37,GenBank,AOW27852,,,SC5314,pst2,chromosome 2,,,,,PHI:124353; PHI:124355; PHI:124356,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,flavodoxin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37732195,PubMed,10.1101/2023.09.05.556406,bioRxiv. 2023 Sep 6:2023.09.05.556406.,james.konopka@stonybrook.edu,Δ/Δ/Δ/Δ (pst1Δ/Δ 153 pst2Δ/Δ pst3Δ/Δ ycp4Δ/Δ) Mut strain had lower kidney fungal burden than the wild-type control strain.,R M Gandra 2023,2023,5 genes,Gandra-2023-The Candida albicans ?-crystallin,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22311,PHI:124355,UniProt,A0A1D8PT02,GenBank,AOW31261,,,SC5314,pst3,chromosome R,,,,,PHI:124353; PHI:124354; PHI:124356,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,flavodoxin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37732195,PubMed,10.1101/2023.09.05.556406,bioRxiv. 2023 Sep 6:2023.09.05.556406.,james.konopka@stonybrook.edu,Δ/Δ/Δ/Δ (pst1Δ/Δ 153 pst2Δ/Δ pst3Δ/Δ ycp4Δ/Δ) Mut strain had lower kidney fungal burden than the wild-type control strain.,R M Gandra 2023,2023,5 genes,Gandra-2023-The Candida albicans ?-crystallin,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22312,PHI:124356,UniProt,A0A1D8PT03,GenBank,AOW31260,,,SC5314,ycp4,chromosome R,,,,,PHI:124353; PHI:124354; PHI:124355,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,flavodoxin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37732195,PubMed,10.1101/2023.09.05.556406,bioRxiv. 2023 Sep 6:2023.09.05.556406.,james.konopka@stonybrook.edu,Δ/Δ/Δ/Δ (pst1Δ/Δ 153 pst2Δ/Δ pst3Δ/Δ ycp4Δ/Δ) Mut strain had lower kidney fungal burden than the wild-type control strain.,R M Gandra 2023,2023,5 genes,Gandra-2023-The Candida albicans ?-crystallin,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22313,PHI:124353,UniProt,A0A1D8PHR5,GenBank,AOW27688,,,SC5314,pst1,chromosome 2,,,,,PHI:124354; PHI:124355; PHI:124356; PHI:124357,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,flavodoxin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37732195,PubMed,10.1101/2023.09.05.556406,bioRxiv. 2023 Sep 6:2023.09.05.556406.,james.konopka@stonybrook.edu,Q Mut (lacking the four FLPs and ZTA1) strain had lower kidney fungal burden than the wild-type control strain.,R M Gandra 2023,2023,5 genes,Gandra-2023-The Candida albicans ?-crystallin,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22314,PHI:124354,UniProt,Q59Y37,GenBank,AOW27852,,,SC5314,pst2,chromosome 2,,,,,PHI:124353; PHI:124355; PHI:124356; PHI:124357,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,flavodoxin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37732195,PubMed,10.1101/2023.09.05.556406,bioRxiv. 2023 Sep 6:2023.09.05.556406.,james.konopka@stonybrook.edu,Q Mut (lacking the four FLPs and ZTA1) strain had lower kidney fungal burden than the wild-type control strain.,R M Gandra 2023,2023,5 genes,Gandra-2023-The Candida albicans ?-crystallin,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22315,PHI:124355,UniProt,A0A1D8PT02,GenBank,AOW31261,,,SC5314,pst3,chromosome R,,,,,PHI:124353; PHI:124354; PHI:124356; PHI:124357,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,flavodoxin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37732195,PubMed,10.1101/2023.09.05.556406,bioRxiv. 2023 Sep 6:2023.09.05.556406.,james.konopka@stonybrook.edu,Q Mut (lacking the four FLPs and ZTA1) strain had lower kidney fungal burden than the wild-type control strain.,R M Gandra 2023,2023,5 genes,Gandra-2023-The Candida albicans ?-crystallin,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22316,PHI:124356,UniProt,A0A1D8PT03,GenBank,AOW31260,,,SC5314,ycp4,chromosome R,,,,,PHI:124353; PHI:124354; PHI:124355; PHI:124357,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,flavodoxin-like protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37732195,PubMed,10.1101/2023.09.05.556406,bioRxiv. 2023 Sep 6:2023.09.05.556406.,james.konopka@stonybrook.edu,Q Mut (lacking the four FLPs and ZTA1) strain had lower kidney fungal burden than the wild-type control strain.,R M Gandra 2023,2023,5 genes,Gandra-2023-The Candida albicans ?-crystallin,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22317,PHI:124357,UniProt,A0A8H6C4D8,GenBank,KAF6063660,,,FDAARGOS_656,Zta1,,,,,,PHI:124353; PHI:124354; PHI:124355; PHI:124356,5476,Candida albicans,,SN152,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,kidney,quinone reductase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37732195,PubMed,10.1101/2023.09.05.556406,bioRxiv. 2023 Sep 6:2023.09.05.556406.,james.konopka@stonybrook.edu,Q Mut (lacking the four FLPs and ZTA1) strain had lower kidney fungal burden than the wild-type control strain.,R M Gandra 2023,2023,5 genes,Gandra-2023-The Candida albicans ?-crystallin,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22318,PHI:124358,UniProt,P96358,GenBank,CCP43794,,,H37Rv,rv1043c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,primates,9606,Homo sapiens (related: human),THP-1 cell line,,,macrophage,effector protein,,,MAPK and NF-κB signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,other evidence,,,NN,37676442,PubMed,10.1007/s10123-023-00428-z,Int Microbiol. 2023 Sep 7.,20116@cqmpc.edu.cn,The intracellular mycobacteria of cell line infected with Msm_Rv1043c were higher than that of macrophages infected with the control strain.,W Li 2023,2023,1 gene,Li-2023-Mycobacterium tuberculosis Rv1043c reg,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22319,PHI:124358,UniProt,P96358,GenBank,CCP43794,,,H37Rv,rv1043c,,,,,,,1773,Mycobacterium tuberculosis,83332,H37Rv,tuberculosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line; C57BL/6,,,macrophage; lung; liver; kidney; spleen,effector protein,,,MAPK and NF-κB signaling pathway,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,other evidence,,,NN,37676442,PubMed,10.1007/s10123-023-00428-z,Int Microbiol. 2023 Sep 7.,20116@cqmpc.edu.cn,"The intracellular mycobacteria of cell line infected with Msm_Rv1043c were higher than that of macrophages infected with the control strain and leads to a bacterial load increase in the lungs, kidneys, livers, and spleens of infected mice.",W Li 2023,2023,1 gene,Li-2023-Mycobacterium tuberculosis Rv1043c reg,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22320,PHI:124359,,no data found,,,,,,MAX79 (Mo_US0071_000070),,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Aichi asahi; cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene mutation,,,NN,37695773,PubMed,10.1371/journal.ppat.1011294,PLoS Pathog. 2023 Sep 11;19(9):e1011294.,stella.cesari@inrae.fr,The disease symptoms caused by the transgenic isolates carrying these effectors were similar to those observed for wild-type Guy11.,M Le Naour-Vernet 2023,2023,3 genes,Le Naour-Vernet-2023-Adaptive evolution in vir,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22321,PHI:124360,,no data found,,,,,,MAX89 ( Mo_US0071_046730),,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Aichi asahi; cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene mutation,,,NN,37695773,PubMed,10.1371/journal.ppat.1011294,PLoS Pathog. 2023 Sep 11;19(9):e1011294.,stella.cesari@inrae.fr,The disease symptoms caused by the transgenic isolates carrying these effectors were similar to those observed for wild-type Guy11.,M Le Naour-Vernet 2023,2023,3 genes,Le Naour-Vernet-2023-Adaptive evolution in vir,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22322,PHI:124361,,no data found,,,,,,MAX83 (Mo_US0071_115900),,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. Aichi asahi; cv. Nipponbare,,,leaf,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene mutation,,,NN,37695773,PubMed,10.1371/journal.ppat.1011294,PLoS Pathog. 2023 Sep 11;19(9):e1011294.,stella.cesari@inrae.fr,The disease symptoms caused by the transgenic isolates carrying these effectors were similar to those observed for wild-type Guy11.,M Le Naour-Vernet 2023,2023,3 genes,Le Naour-Vernet-2023-Adaptive evolution in vir,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22323,PHI:124362,UniProt,P26477,GenBank,AAA27075,,,LT2,flgM,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,ΔflgM infected mice had significantly reduced bacterial burden in all tissues compared to wild type.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22324,PHI:124363,UniProt,P06179,GenBank,AAL20871,,,LT2,fliC,,,,,,PHI:124364,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,flagellar biosynthesis; flagellin,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,ΔfliC/fliB infected mice had significantly increased bacterial burden in all tissues compared to wild type.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22325,PHI:124364,UniProt,P52616,GenBank,AAL21657,,,LT2,fljB,,,,,,PHI:124363,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,filament structural protein,,,,increased virulence (hypervirulence),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,ΔfliC/fliB infected mice had significantly increased bacterial burden in all tissues compared to wild type.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22326,PHI:124365,UniProt,E1WAC8,GenBank,AAA75170,,,SL1344,SPI-1,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,type III secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,"ΔSPI-1 infected mice had significantly reduced bacterial burden in allthe spleen, mLN, cecum and liver compared to wild type.",A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22327,PHI:124362,UniProt,P26477,GenBank,AAA27075,,,LT2,flgM,,,,,,PHI:124365,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,ΔflgM/ SPI-1 infected mice had significantly reduced bacterial burden in all tissues compared to wild type.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22328,PHI:124365,UniProt,E1WAC8,GenBank,AAA75170,,,SL1344,SPI-1,,,,,,PHI:124362,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,type III secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,ΔflgM/ SPI-1 infected mice had significantly reduced bacterial burden in all tissues compared to wild type.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22329,PHI:124362,UniProt,P26477,GenBank,AAA27075,,,LT2,flgM,,,,,,PHI:124366,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,ΔflgM/ flgB infected mice had same as wikd type bacterial burden in all tissues.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22330,PHI:124366,UniProt,P16437,GenBank,BAA02861,,,LT2,flgB,,,,,,PHI:124362,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,ΔflgM/ flgB infected mice had same as wikd type bacterial burden in all tissues.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22331,PHI:124362,UniProt,P26477,GenBank,AAA27075,,,LT2,flgM,,,,,,PHI:124363; PHI:124364,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,flagellin,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,ΔflgM/fliC/fliB infected mice had same bacterial burden in all tissues compared to wild type.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22332,PHI:124363,UniProt,P06179,GenBank,AAL20871,,,LT2,fliC,,,,,,PHI:124362; PHI:124364,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,flagellar biosynthesis; flagellin,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,ΔflgM/fliC/fliB infected mice had same bacterial burden in all tissues compared to wild type.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22333,PHI:124364,UniProt,P52616,GenBank,AAL21657,,,LT2,fljB,,,,,,PHI:124362; PHI:124363,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen; mesenteric lymph node; cecum,filament structural protein,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,ΔflgM/fliC/fliB infected mice had same bacterial burden in all tissues compared to wild type.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22334,PHI:124367,UniProt,O84947,GenBank,CAA12187,,,LT2,SPI-2,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,mesenteric lymph node; cecum,type III secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,B6 mice infected with ΔSPI-2 had significantly lower pathogen burden.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22335,PHI:124367,UniProt,O84947,GenBank,CAA12187,,,LT2,SPI-2,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,type III secretion system,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,B6 mice infected with ΔSPI-2 had no pathogen burden.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22336,PHI:124362,UniProt,P26477,GenBank,AAA27075,,,LT2,flgM,,,,,,PHI:124367,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,flagellin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,B6 mice infected with ΔflgM/SPI-2 had no pathogen burden.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22337,PHI:124367,UniProt,O84947,GenBank,CAA12187,,,LT2,SPI-2,,,,,,PHI:124362,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,liver; spleen,type III secretion system,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,B6 mice infected with ΔflgM/SPI-2 had no pathogen burden.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22338,PHI:124362,UniProt,P26477,GenBank,AAA27075,,,LT2,flgM,,,,,,PHI:124367,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node,flagellin,,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,B6 mice infected with ΔflgM/SPI-2 had lower pathogen burden.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22339,PHI:124367,UniProt,O84947,GenBank,CAA12187,,,LT2,SPI-2,,,,,,PHI:124362,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,cecum; mesenteric lymph node,type III secretion system,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37638725,PubMed,10.1128/iai.00255-23,Infect Immun. 2023 Sep 14;91(9):e0025523.,kelsmith@uw.edu,B6 mice infected with ΔflgM/SPI-2 had lower pathogen burden.,A H López-Yglesias 2023,2023,6 genes,L?pez-Yglesias-2023-FlgM is required to evade,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22340,PHI:124368,UniProt,J9VVE4,GenBank,AFR98238,,,H99,Cmp1 (CNAG_06000),chromosome 12,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,mannoprotein,,,,reduced virulence,,,,,,,,,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium nitrite (NaNO2);sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium nitrite (NaNO2): CHEBI:78870; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,33114434,PubMed,10.3390/pathogens9110881,Pathogens. 2020 Oct 24;9(11):881.,tongbaoliu@swu.edu.cn,Cmp1Δ mutant or the CMP1 overexpression strain was significantly attenuated in a murine inhalation model of cryptococcosis.,L T Han 2020,2020,1 gene,Han-2020-A Predicted Mannoprotein Cmp1 Regulat,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22341,PHI:124368,UniProt,J9VVE4,GenBank,AFR98238,,,H99,Cmp1 (CNAG_06000),chromosome 12,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),C57BL/6,,,lung,mannoprotein,,,,reduced virulence,,,,,,,,,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium nitrite (NaNO2);sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium nitrite (NaNO2): CHEBI:78870; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: overexpression,,,NN,33114434,PubMed,10.3390/pathogens9110881,Pathogens. 2020 Oct 24;9(11):881.,tongbaoliu@swu.edu.cn,Cmp1Δ mutant or the CMP1 overexpression strain was significantly attenuated in a murine inhalation model of cryptococcosis.,L T Han 2020,2020,1 gene,Han-2020-A Predicted Mannoprotein Cmp1 Regulat,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22342,PHI:124368,UniProt,J9VVE4,GenBank,AFR98238,,,H99,Cmp1 (CNAG_06000),chromosome 12,,,,,,5207,Cryptococcus neoformans,235443,H99,fungal meningitis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,mannoprotein,,,,unaffected pathogenicity,,,,,,,,,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium nitrite (NaNO2);sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium nitrite (NaNO2): CHEBI:78870; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,33114434,PubMed,10.3390/pathogens9110881,Pathogens. 2020 Oct 24;9(11):881.,tongbaoliu@swu.edu.cn,Cmp1Δ mutant or the CMP1 overexpression strain was significantly attenuated in a murine inhalation model of cryptococcosis.,L T Han 2020,2020,1 gene,Han-2020-A Predicted Mannoprotein Cmp1 Regulat,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22343,PHI:124369,UniProt,E1WAC0,GenBank,AAD21081,,,SL1344,hilD,,,,,,,28901,Salmonella enterica,216597,subsp. enterica serovar Typhimurium strain SL1344,salmonellosis,rodents,10090,Mus musculus (related: house mouse),C57BL/6J,,,gut,transcriptional regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37651408,PubMed,10.1371/journal.pbio.3002253,PLoS Biol. 2023 Aug 31;21(8):e3002253.,hardt@micro.biol.ethz.ch,hilD mutant have a reduced virulence compared to wild-type S. Typhimurium.,E Gül 2023,2023,1 gene,G?l-2023-The microbiota conditions a gut milie,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22344,PHI:124370,UniProt,Q4W9V1,GenBank,EAL84512,,,Af293,erg6,chromosome 4,,,,,,746128,Aspergillus fumigatus,,ku80 ΔpyrG (ΔakuB),invasive pulmonary aspergillosis,rodents,10090,Mus musculus (related: house mouse),CD-1,,,lung,C-24 methyltransferase encoding gene,,,ergosterol biosynthesis pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37609350,PubMed,10.1101/2023.08.08.552489,bioRxiv. 2023 Aug 9:2023.08.08.552489.,jfortwen@uthsc.edu,Repression of erg6 reduces fungal burden in a murine model of invasive aspergillosis,J Xie 2023,2023,1 gene,Xie-2023-The sterol C-24 methyltransferase enc,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22345,PHI:124371,,no data found,,,,,,Aagp (BFP66_RS01250),,,,,,,1307,Streptococcus suis,,GZ0565,streptococcal toxic shock syndrome,rodents,10090,Mus musculus (related: house mouse),SPF CD-1,,,blood; liver; brain; heart; kidney,aquaporin,,,no data foundPhosphorylation pathway,reduced virulence,,,,,,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37621097,PubMed,10.1080/21505594.2023.2249789,Virulence. 2023 Dec;14(1):2249789.,wuzongfu@njau.edu.cn,"Compared with WT infection groups, the number of ΔAagp in blood, liver, spleen, kidney, and brain tissues was significantly reduced, indicating that Aagp contributes to S. suis virulence.",X Zhu 2023,2023,1 gene,Zhu-2023-A novel aquaporin Aagp contributes to,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22346,PHI:124372,UniProt,D0ZC05,GenBank,ACY83406,,,EIB202,Trx2 (ETAE_0559),,,,,,,636,Edwardsiella tarda,,PPD130/91,hemorrhagic septicemia,bony fishes,96903,Trichopodus trichopterus (related: Three spot gourami),,,,,effector protein,,,NF-κB pathway,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37642418,PubMed,10.1128/msphere.00346-23,mSphere. 2023 Aug 29:e0034623.,xieh@ihb.ac.cn,Trx2 significantly attenuates E. piscicida virulence in a fish infection model.,X J Liao 2023,2023,1 gene,Liao-2023-Unraveling and characterization of n,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22347,PHI:124373,UniProt,A0A063C075,GenBank,GAO14046,,,IPU010,HST2 (UV8b_01862),,,,,,,1159556,Ustilaginoidea virens,,P1,false smut (rice),monocots,4530,Oryza sativa (related: rice),cv. Liangyoupeijiu 9,,,panicle,histone deacetylase,,,,reduced virulence,,,,,few fewer false smut balls,reduced,,reduced ; defective,,no,sorbitol;hydrogen peroxide (H2O2),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37615365,PubMed,10.1021/acs.jafc.3c01782,J Agric Food Chem. 2023 Sep 6;71(35):13124-13136.,wxs@ cau.edu.cn,"ΔUvhst2 mutant generated few fewer false smut balls on inoculated panicles than did the wild-type strain, whereas the complementation strain partially restored the ability to produce false smut balls.",L Liu 2023,2023,1 gene,Liu-2023-Histone Deacetylase UvHST2 Is a Globa,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22348,PHI:124374,UniProt,P0DJM0,GenBank,AAA25289,,,EGD,InlA,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,liver; spleen; muscle,internalin A,,,HIF-1α signalling pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37681973,PubMed,10.1128/spectrum.01405-23,Microbiol Spectr. 2023 Sep 8:e0140523.,songhh@zafu.edu.cn,"Compared to wild type, bacterial count in InlA mutant seems to be decreased in hypoxia condition.",J Wang 2023,2023,2 genes,Wang-2023-Hypoxia-induced HIF-1? promotes List,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22349,PHI:124375,UniProt,P0DQD3,GenBank,AAA25290,,,EGD,InlB,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,bony fishes,8128,Oreochromis niloticus (related: nile tilapia),,,,liver; spleen; muscle,internalin B,,,HIF-1α signalling pathway,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37681973,PubMed,10.1128/spectrum.01405-23,Microbiol Spectr. 2023 Sep 8:e0140523.,songhh@zafu.edu.cn,"Compared to wild type, bacterial count in InlB mutant seems to be decreased in hypoxia condition.",J Wang 2023,2023,2 genes,Wang-2023-Hypoxia-induced HIF-1? promotes List,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22350,PHI:124376,,no data found,GenBank,PEG01338,,,AFS089527,EnaA,,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaA was similar to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22351,PHI:124377,,no data found,GenBank,PEG09496,,,AFS089520,EnaB,,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaB was similar to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22352,PHI:124378,,no data found,GenBank,PEG10401,,,AFS089520,EnaC,,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaC was similar to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22353,PHI:124376,,no data found,GenBank,PEG01338,,,AFS089527,EnaA,,,,,,PHI:124377,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaAB was similar to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22354,PHI:124377,,no data found,GenBank,PEG09496,,,AFS089520,EnaB,,,,,,PHI:124376,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaAB was similar to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22355,PHI:124377,,no data found,GenBank,PEG09496,,,AFS089520,EnaB,,,,,,PHI:124378,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaBC was significantly reduced by 10.2–14.8% compared to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22356,PHI:124378,,no data found,GenBank,PEG10401,,,AFS089520,EnaC,,,,,,PHI:124377,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaBC was significantly reduced by 10.2–14.8% compared to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22357,PHI:124376,,no data found,GenBank,PEG01338,,,AFS089527,EnaA,,,,,,PHI:124378,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaAC was significantly reduced by 10.2–14.8% compared to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22358,PHI:124378,,no data found,GenBank,PEG10401,,,AFS089520,EnaC,,,,,,PHI:124376,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaAC was significantly reduced by 10.2–14.8% compared to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22359,PHI:124376,,no data found,GenBank,PEG01338,,,AFS089527,EnaA,,,,,,PHI:124377; PHI:124378,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaABC was significantly reduced by 10.2–14.8% compared to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22360,PHI:124377,,no data found,GenBank,PEG09496,,,AFS089520,EnaB,,,,,,PHI:124376; PHI:124378,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaABC was significantly reduced by 10.2–14.8% compared to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22361,PHI:124378,,no data found,GenBank,PEG10401,,,AFS089520,EnaC,,,,,,PHI:124376; PHI:124377,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,fruit,ena family gene,,,pacC-mediated pH signaling pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37623577,PubMed,10.3390/jof9080806,J Fungi (Basel). 2023 Jul 30;9(8):806.,bqli@ibcas.ac.cn,Lesion diameters of ΔPeEnaC was similar to WT.,R Zhuo 2023,2023,3 genes,Zhuo-2023-Ena Proteins Respond to PacC-Mediate,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22362,PHI:124379,UniProt,A0A125YP82,GenBank,EPT25418,,,ME49,MAPR (TGME49_276990),chromosome XII,,,,,,5811,Toxoplasma gondii,383379,383379,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,membrane-associated progesterone receptor,,,steroidogenic pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37651449,PubMed,10.1371/journal.ppat.1011566,PLoS Pathog. 2023 Aug 31;19(8):e1011566.,icoppens@jhsph.edu,"All mice infected with ΔTgMAPR died after 17–18 days regardless of their time in culture, indicating reduced of virulence for the mutant.",B Asady 2023,2023,2 genes,Asady-2023-Function and regulation of a steroi,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22363,PHI:124380,UniProt,S8EQL7,GenBank,EPT25706,,,ME49,CYP450 (TGME49_315770),chromosome XI,,,,,,5811,Toxoplasma gondii,383379,383379,toxoplasmosis,rodents,10090,Mus musculus (related: house mouse),Swiss Webster,,,,cytochrome p450,,,steroidogenic pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37651449,PubMed,10.1371/journal.ppat.1011566,PLoS Pathog. 2023 Aug 31;19(8):e1011566.,icoppens@jhsph.edu,"Compared to wild-type parasites, iΔTgCYP450mt lost virulence in mice.",B Asady 2023,2023,2 genes,Asady-2023-Function and regulation of a steroi,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22364,PHI:124381,UniProt,P0C0J0,GenBank,AAA26978,,,86858,SpeB,,,,,,,1314,Streptococcus pyogenes,1235829,A-20,infection,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,cysteine protease,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37621107,PubMed,10.1080/21505594.2023.2249784,Virulence. 2023 Dec;14(1):2249784.,entchuan@gap.cgu.edu.tw,speB mutant significantly decreased cytotoxicity compared to wild type.,C Chiang-Ni 2023,2023,2 genes,Chiang-Ni-2023-RopB-regulated SpeB cysteine pr,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22365,PHI:124382,UniProt,P0C0I3,GenBank,AAK33267,,,SF370,slo,,,,,,,1314,Streptococcus pyogenes,1235829,A-20,infection,primates,9606,Homo sapiens (related: human),HaCaT cell line,,,keratinocyte,streptolysin O,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37621107,PubMed,10.1080/21505594.2023.2249784,Virulence. 2023 Dec;14(1):2249784.,entchuan@gap.cgu.edu.tw,slo mutant significantly decreased cytotoxicity compared to wild type.,C Chiang-Ni 2023,2023,2 genes,Chiang-Ni-2023-RopB-regulated SpeB cysteine pr,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22366,PHI:124383,UniProt,A0A9E9PC95,GenBank,WAX42085,,,AOR07_HL,GigC,,,,,,,470,Acinetobacter baumannii,1116234,AB5075,nosocomial infection,rodents,10090,Mus musculus (related: house mouse),C57BL/6J; BALB/c,,,,LysR family regulator,,,cysteine biosynthesis pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33077621,PubMed,10.1128/IAI.00180-20,Infect Immun. 2020 Dec 15;89(1):e00180-20.,michael.gebhardt@childrens.harvard.edu,"Compared to wils type, mice infected with the isogenic AB5075 ΔgigC strain survived for the duration of the experiment.",M J Gebhardt 2020,2020,1 gene,"Gebhardt-2020-GigC, a LysR-family Transcriptio",BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22367,PHI:124384,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671453,PubMed,10.1080/22221751.2023.2254415,Emerg Microbes Infect. 2023 Dec;12(2):2254415.,gaop0305@gmail.com,saeR knockdown strain reduced the size of the abscess and decreased the bacterial burden significantly.,P Gao 2023,2023,4 genes,Gao-2023-SaeR as a novel target for antivirule,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22368,PHI:124385,UniProt,Q2G2U1,GenBank,CAD89115,,,ISP479C,saeS,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,sensory kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671453,PubMed,10.1080/22221751.2023.2254415,Emerg Microbes Infect. 2023 Dec;12(2):2254415.,gaop0305@gmail.com,saeS knockdown strain reduced the size of the abscess and decreased the bacterial burden significantly.,P Gao 2023,2023,4 genes,Gao-2023-SaeR as a novel target for antivirule,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22369,PHI:124386,UniProt,Q2G2G1,GenBank,ATV03510,,,O11,saeQ,,,,,,PHI:124384; PHI:124385,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,transmembrane protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671453,PubMed,10.1080/22221751.2023.2254415,Emerg Microbes Infect. 2023 Dec;12(2):2254415.,gaop0305@gmail.com,saeQRS knockdown strain reduced the size of the abscess and decreased the bacterial burden significantly.,P Gao 2023,2023,4 genes,Gao-2023-SaeR as a novel target for antivirule,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22370,PHI:124384,UniProt,Q2G2G2,GenBank,CAD89114,,,ISP479C,saeR,,,,,,PHI:124385; PHI:124386,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,response regulator,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671453,PubMed,10.1080/22221751.2023.2254415,Emerg Microbes Infect. 2023 Dec;12(2):2254415.,gaop0305@gmail.com,saeQRS knockdown strain reduced the size of the abscess and decreased the bacterial burden significantly.,P Gao 2023,2023,4 genes,Gao-2023-SaeR as a novel target for antivirule,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22371,PHI:124385,UniProt,Q2G2U1,GenBank,CAD89115,,,ISP479C,saeS,,,,,,PHI:124384; PHI:124386,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,sensory kinase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671453,PubMed,10.1080/22221751.2023.2254415,Emerg Microbes Infect. 2023 Dec;12(2):2254415.,gaop0305@gmail.com,saeQRS knockdown strain reduced the size of the abscess and decreased the bacterial burden significantly.,P Gao 2023,2023,4 genes,Gao-2023-SaeR as a novel target for antivirule,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22372,PHI:124387,UniProt,P0A0I5,GenBank,BAB43126,,,N315,agrA,,,,,,,1280,Staphylococcus aureus,367830,USA300,skin infection; food poisoning; respiratory disease,rodents,10090,Mus musculus (related: house mouse),BALB/c,,,skin,accessory gene regulator protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37671453,PubMed,10.1080/22221751.2023.2254415,Emerg Microbes Infect. 2023 Dec;12(2):2254415.,gaop0305@gmail.com,agrA knockdown strain reduced the size of the abscess and decreased the bacterial burden significantly.,P Gao 2023,2023,4 genes,Gao-2023-SaeR as a novel target for antivirule,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22373,PHI:124388,,no data found,,,,,,VmPacC,,,,,,,105487,Valsa mali,,03-8,Valsa canker (apple),eudicots,3750,Malus domestica (related: apple),cv. Fuji,,,leaf; twig,transcription factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37676527,PubMed,10.1007/s44154-023-00097-y,Stress Biol. 2023 Jun 21;3(1):18. doi: 10.1007/s44154-023-00097-y,liangsheng.xu@nwafu.edu.cn,Expression of pectinase genes increased in deletion mutant during infection.,L Xu 2023,2023,1 gene,Xu-2023-VmPacC-mediated pH regulation of Valsa,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22374,PHI:124389,UniProt,O67996,,,,,,bvrR (BAW_12006),,,,,,PHI:69,235,Brucella abortus,,2308W,brucellosis,primates,9606,Homo sapiens (related: human),HeLa cell line,,,epithelial cell,two-component system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37630574,PubMed,10.3390/microorganisms11082014,Microorganisms. 2023 Aug 5;11(8):2014.,orivas@itcr.ac.cr,"B. abortus 2308W was able to replicate intracellularly in both types of cells, but B. abortus ΔbvrRS did not.",O Rivas-Solano 2023,2023,2 genes,Rivas-Solano-2023-A bvrR_bvrS Non-Polar Brucel,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22375,PHI:124390,UniProt,O68164,,,,,,bvrS (BAW_12007),,,,,,PHI:68,235,Brucella abortus,,2308W,brucellosis,rodents,10090,Mus musculus (related: house mouse),RAW 264.7 cell line,,,macrophage,two-component system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37630574,PubMed,10.3390/microorganisms11082014,Microorganisms. 2023 Aug 5;11(8):2014.,orivas@itcr.ac.cr,"B. abortus 2308W was able to replicate intracellularly in both types of cells, but B. abortus ΔbvrRS did not.",O Rivas-Solano 2023,2023,2 genes,Rivas-Solano-2023-A bvrR_bvrS Non-Polar Brucel,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22376,PHI:124391,UniProt,I2G242,GenBank,UHOR_02675,,,,Ribo1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,secreted protein,,,,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene complementation; altered gene expression / gene regulation: overexpression,,,NN,37680042,PubMed,10.1111/nph.19244,New Phytol. 2023 Sep 7. doi: 10.1111/nph.19244. Online ahead of print,g.doehlemann@uni-koeln.de,SG200-OE-Ribo1M showed reduced virulence compared with SG200.,B Ökmen 2023,2023,1 gene,?kmen-2023-A conserved extracellular Ribo1 wit,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22377,PHI:124391,UniProt,I2G242,GenBank,UHOR_02675,,,,Ribo1,,,,,,,5270,Ustilago maydis,,SG200,smut,monocots,4577,Zea mays (related: maize),cv. Early Golden Bantam,,,leaf,secreted protein,,,,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37680042,PubMed,10.1111/nph.19244,New Phytol. 2023 Sep 7. doi: 10.1111/nph.19244. Online ahead of print,g.doehlemann@uni-koeln.de,SG200Δribo1 mutant strain showed a significant reduction in virulence compared with SG200.,B Ökmen 2023,2023,1 gene,?kmen-2023-A conserved extracellular Ribo1 wit,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22378,PHI:124392,UniProt,A0A1J0M9G6,,,,,,wzc,,AB60 - Mutation from guanine (G) to cytosine (C) at position 1619 of wzc,,,,,470,Acinetobacter baumannii,,ST369,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,multidrug-resistant factor,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene mutation,,,NN,37655924,PubMed,10.1128/msystems.00731-23,mSystems. 2023 Sep 1:e0073123.,no data foundsunb@ustc.edu.cn,"AB60-wzc gene of A. baumannii ST369 that doesn""t affect bacterial virulence and viscosity.",Y Huang 2023,2023,1 gene,Huang-2023-Epidemiological characteristics of,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22379,PHI:124392,UniProt,A0A1J0M9G6,,,,,,wzc,,AB46- Gly to Ala at the 540th encoded amino acid,,,,,470,Acinetobacter baumannii,,ST369,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,multidrug-resistant factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,NN,37655924,PubMed,10.1128/msystems.00731-23,mSystems. 2023 Sep 1:e0073123.,no data foundsunb@ustc.edu.cn,"G540A, on the wzc gene of A. baumannii ST369 that can potentially affect bacterial virulence and viscosity.",Y Huang 2023,2023,1 gene,Huang-2023-Epidemiological characteristics of,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22380,PHI:124392,UniProt,A0A1J0M9G6,,,,,,wzc,,AB152- Gly to Asp at the 667th amino acid,,,,,470,Acinetobacter baumannii,,ST369,nosocomial infection,moths,7137,Galleria mellonella (related: greater wax moth),,,,larva,multidrug-resistant factor,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene mutation,,,NN,37655924,PubMed,10.1128/msystems.00731-23,mSystems. 2023 Sep 1:e0073123.,no data foundsunb@ustc.edu.cn,"G667D, on the wzc gene of A. baumannii ST369 that can potentially affect bacterial virulence and viscosity.",Y Huang 2023,2023,1 gene,Huang-2023-Epidemiological characteristics of,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22381,PHI:124393,UniProt,G4MSK3,GenBank,EHA54619,,,70-15,MET2 (MGG_01469),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,methionine biosynthesis enzyme,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,ΔMomet2 mutant was significantly reduced in the infection of rice.,H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22382,PHI:124394,UniProt,G4NK78,GenBank,EHA45801,,,70-15,CYS2 (MGG_14202),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,homoserine O-acetyltransferase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,ΔMocys2 mutant was significantly reduced in the infection of rice.,H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22383,PHI:124393,UniProt,G4MSK3,GenBank,EHA54619,,,70-15,MET2 (MGG_01469),chromosome 2,,,,,PHI:124394,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,methionine biosynthesis enzyme,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,ΔMocys2Momet2 mutant was same as wild type in the infection of rice.,H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22384,PHI:124394,UniProt,G4NK78,GenBank,EHA45801,,,70-15,CYS2 (MGG_14202),chromosome 7,,,,,PHI:124393,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,homoserine O-acetyltransferase,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,ΔMocys2Momet2 mutant was same as wild type in the infection of rice.,H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22385,PHI:124393,UniProt,G4MSK3,GenBank,EHA54619,,,70-15,MET2 (MGG_01469),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,methionine biosynthesis enzyme,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,ΔMomet2 mutant displayed no obvious lesions.,H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22386,PHI:124394,UniProt,G4NK78,GenBank,EHA45801,,,70-15,CYS2 (MGG_14202),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,homoserine O-acetyltransferase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,"The ΔMocys2 mutant exhibited very restricted lesions on unwounded leaves,",H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22387,PHI:124393,UniProt,G4MSK3,GenBank,EHA54619,,,70-15,MET2 (MGG_01469),chromosome 2,,,,,PHI:124394,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,methionine biosynthesis enzyme,,,,loss of pathogenicity,,,,,no lesion,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,ΔΔMocys2Momet2 mutants displayed no obvious lesions.,H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22388,PHI:124394,UniProt,G4NK78,GenBank,EHA45801,,,70-15,CYS2 (MGG_14202),chromosome 7,,,,,PHI:124393,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4513,Hordeum vulgare (related: barley),cv. Four-arris,,,leaf,homoserine O-acetyltransferase,,,,loss of pathogenicity,,,,,no lesion,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,ΔΔMocys2Momet2 mutants displayed no obvious lesions.,H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22389,PHI:124395,UniProt,G4NER7,GenBank,EHA49490,,,70-15,GLIK (MGG_00068),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,glutamylcyclotransferase,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,The ΔMoglik mutant displayed significantly reduced virulence while the complemented strain was similar to WT.,H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22390,PHI:124396,UniProt,G4N2T5,GenBank,EHA53384,,,70-15,CDH-CYT (MGG_07949),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,cellobiose dehydrogenase cytochrome domain-containing protein,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,Mocdh-cyt mutant displayed a significantly reduced virulence in comparison to the WT and complemented strains.,H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22391,PHI:124393,UniProt,G4MSK3,GenBank,EHA54619,,,70-15,MET2 (MGG_01469),chromosome 2,,,,,PHI:124394,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,methionine biosynthesis enzyme,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,"At 7d post-inoculation (dpi), the HIGS-MoCYS2-MET2 plants produced significantly smaller lesions than CK.",H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22392,PHI:124394,UniProt,G4NK78,GenBank,EHA45801,,,70-15,CYS2 (MGG_14202),chromosome 7,,,,,PHI:124393,318829,Magnaporthe oryzae,,Guy11,blast (rice),monocots,4530,Oryza sativa (related: rice),cv. CO-39,,,leaf,homoserine O-acetyltransferase,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37733784,PubMed,10.1371/journal.pgen.1010927,PLoS Genet. 2023 Sep 21;19(9):e1010927.,zhgzhang@njau.edu.cn,"At 7d post-inoculation (dpi), the HIGS-MoCYS2-MET2 plants produced significantly smaller lesions than CK.",H Li 2023,2023,4 genes,Li-2023-Methionine biosynthesis enzyme MoMet2,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22393,PHI:124395,,no data found,,,,,,AP1 (PEG01534),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,transcriptional factor,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,reduced,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,"Deletion of PeAP1 results in increased sensitivity to H2O2, and PeAP1 mutants exhibit a variety of defects in hyphal growth and virulence.",Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22394,PHI:124395,,no data found,,,,,,AP1 (PEG01534),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,23211,Pyrus communis (related: pear),,,,fruit,transcriptional factor,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,reduced,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,"Deletion of PeAP1 results in increased sensitivity to H2O2, and PeAP1 mutants exhibit a variety of defects in hyphal growth and virulence.",Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22395,PHI:124396,,no data found,,,,,,Prx2 (PEG05350),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,23211,Pyrus communis (related: pear),,,,fruit,peroxiredoxin gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,reduced,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,"ΔPePrx2 strain exhibited abnormal mycelial morphology, reduced mycelial growth and reduced virulence on pear fruit.",Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22396,PHI:124396,,no data found,,,,,,Prx2 (PEG05350),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,peroxiredoxin gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,reduced,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,"ΔPePrx2 strain exhibited abnormal mycelial morphology, reduced mycelial growth and reduced virulence on apple fruit.",Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22397,PHI:124397,,no data found,,,,,,TRX2 (PEG05529),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,thioredoxin gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,reduced,,reduced,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,ΔPeTrx2 strain stimulated mycelial growth but significantly inhibited conidiation and reduced virulence on apple fruit.,Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22398,PHI:124397,,no data found,,,,,,TRX2 (PEG05529),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,23211,Pyrus communis (related: pear),,,,fruit,thioredoxin gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,reduced,,reduced,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,ΔPeTrx2 strain stimulated mycelial growth but significantly inhibited conidiation and reduced virulence on pear fruit.,Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22399,PHI:124398,,no data found,,,,,,GST1 (PEG08383),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,glutathione S-transferase gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,wild type,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,Disruption of PeGST1 resulted in attenuated virulence on fruit but did not affect mycelial growth and conidiation in vitro.,Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22400,PHI:124398,,no data found,,,,,,GST1 (PEG08383),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,23211,Pyrus communis (related: pear),,,,fruit,glutathione S-transferase gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,wild type,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,Disruption of PeGST1 resulted in attenuated virulence on fruit but did not affect mycelial growth and conidiation in vitro.,Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22401,PHI:124399,,no data found,,,,,,Prx1 (PEG03317),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,peroxiredoxin gene,,,antioxidant pathway,unaffected pathogenicity,,,,,wild type,wild type,,wild type,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,ΔPePrx1 strain exhibited showed unaffected virulence on apple fruit.,Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22402,PHI:124399,,no data found,,,,,,Prx1 (PEG03317),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,23211,Pyrus communis (related: pear),,,,fruit,peroxiredoxin gene,,,antioxidant pathway,unaffected pathogenicity,,,,,wild type,wild type,,wild type,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,ΔPePrx1 strain exhibited showed unaffected virulence on pear fruit.,Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22403,PHI:124396,,no data found,,,,,,Prx2 (PEG05350),,,,,,PHI:124399,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,peroxiredoxin gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,reduced,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,ΔPePrx1/2 double mutants exhibited a phenotype with more conspicuous reductions in mycelial growth and virulence than any single knockout mutant of PePrxs.,Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22404,PHI:124399,,no data found,,,,,,Prx1 (PEG03317),,,,,,PHI:124396,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,peroxiredoxin gene,,,antioxidant pathway,reduced virulence,,,,,smaller necrotic area,wild type,,reduced,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,ΔPePrx1/2 double mutants exhibited a phenotype with more conspicuous reductions in mycelial growth and virulence than any single knockout mutant of PePrxs.,Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22405,PHI:124396,,no data found,,,,,,Prx2 (PEG05350),,,,,,PHI:124399,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,23211,Pyrus communis (related: pear),,,,fruit,peroxiredoxin gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,reduced,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,ΔPePrx1/2 double mutants exhibited a phenotype with more conspicuous reductions in mycelial growth and virulence than any single knockout mutant of PePrxs.,Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22406,PHI:124399,,no data found,,,,,,Prx1 (PEG03317),,,,,,PHI:124396,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,23211,Pyrus communis (related: pear),,,,fruit,peroxiredoxin gene,,,antioxidant pathway,reduced virulence,,,,,smaller necrotic area,wild type,,reduced,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,ΔPePrx1/2 double mutants exhibited a phenotype with more conspicuous reductions in mycelial growth and virulence than any single knockout mutant of PePrxs.,Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22407,PHI:124398,,no data found,,,,,,GST1 (PEG08383),,,,,,PHI:124400,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,glutathione S-transferase gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,wild type,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,"No apparent defect in mycelial growth was observed, but virulence was reduced ΔPeGST1/5.",Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22408,PHI:124400,,no data found,,,,,,GST5 (PEG08441),,,,,,PHI:124398,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,glutathione S-transferase gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,wild type,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,"No apparent defect in mycelial growth was observed, but virulence was reduced ΔPeGST1/5.",Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22409,PHI:124398,,no data found,,,,,,GST1 (PEG08383),,,,,,PHI:124400,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,23211,Pyrus communis (related: pear),,,,fruit,glutathione S-transferase gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,wild type,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,"No apparent defect in mycelial growth was observed, but virulence was reduced ΔPeGST1/5.",Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22410,PHI:124400,,no data found,,,,,,GST5 (PEG08441),,,,,,PHI:124398,27334,Penicillium expansum,1407458,T01,blue mold,eudicots,23211,Pyrus communis (related: pear),,,,fruit,glutathione S-transferase gene,,,antioxidant pathway,reduced virulence,,,,,small necrotic lesions,wild type,,wild type,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,37732795,PubMed,10.1128/spectrum.03808-22,Microbiol Spectr. 2023 Sep 21:e0380822.,tsp@ibcas.ac.cn,"No apparent defect in mycelial growth was observed, but virulence was reduced ΔPeGST1/5.",Y Chen 2023,2023,6 genes,Chen-2023-PeAP1-mediated oxidative stress resp,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22411,PHI:124401,,no data found,,,,,,BCS7_RS07420,,,,,,,554,Pectobacterium carotovorum,,subsp. odoriferum strain BCS7,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,AraC family transcriptional regulator,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,37712699,PubMed,10.1128/spectrum.01764-23,Microbiol Spectr. 2023 Sep 15:e0176423.,fanjq@njau.edu.cn,Single gene mutant Δ07420 did not differ relative to the wild-type (WT) control (Po BCS7).,C Chen 2023,2023,2 genes,Chen-2023-A genome-wide association study reve,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22412,PHI:124402,,no data found,,,,,,BCS7_RS15950,,,,,,,554,Pectobacterium carotovorum,,subsp. odoriferum strain BCS7,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,iron ABC transporter permease,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,37712699,PubMed,10.1128/spectrum.01764-23,Microbiol Spectr. 2023 Sep 15:e0176423.,fanjq@njau.edu.cn,Single gene mutant Δ15350 did not differ relative to the wild-type (WT) control (Po BCS7).,C Chen 2023,2023,2 genes,Chen-2023-A genome-wide association study reve,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22413,PHI:124401,,no data found,,,,,,BCS7_RS07420,,,,,,PHI:124402,554,Pectobacterium carotovorum,,subsp. odoriferum strain BCS7,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,AraC family transcriptional regulator,,,,reduced virulence,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,37712699,PubMed,10.1128/spectrum.01764-23,Microbiol Spectr. 2023 Sep 15:e0176423.,fanjq@njau.edu.cn,Double mutant Δ15950/07420 exhibited greater virulence.,C Chen 2023,2023,2 genes,Chen-2023-A genome-wide association study reve,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22414,PHI:124402,,no data found,,,,,,BCS7_RS15950,,,,,,PHI:124401,554,Pectobacterium carotovorum,,subsp. odoriferum strain BCS7,soft rot,eudicots,3711,Brassica rapa (related: field mustard),subsp. pekinensis (chinese cabbage),,,petiole,iron ABC transporter permease,,,,increased virulence (hypervirulence),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,37712699,PubMed,10.1128/spectrum.01764-23,Microbiol Spectr. 2023 Sep 15:e0176423.,fanjq@njau.edu.cn,Double mutant Δ15950/07420 exhibited greater virulence.,C Chen 2023,2023,2 genes,Chen-2023-A genome-wide association study reve,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22415,PHI:124403,UniProt,Q71VZ1,GenBank,AAT05525,,,F2365,gshF,,,,,,,1639,Listeria monocytogenes,169963,EGD-e,listeriosis,rodents,10090,Mus musculus (related: house mouse),ICR,,,liver; spleen,glutathione synthase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37668404,PubMed,10.1128/spectrum.02365-23,Microbiol Spectr. 2023 Sep 5:e0236523.,songhh@zafu.edu.cn,Mice infected with the gshF deletion strain exhibited lower bacterial loads compared to those infected with the EGD-e strain.,M Chen 2023,2023,1 gene,Chen-2023-Listeria monocytogenes GshF contribu,BATCH_126A,2023-10-01,MC,,,,,,,,,,,,,
,,Record 22416,PHI:124404,UniProt,A1TID8,GenBank,ABM30726,,,AAC00-1,AopU (ABM30726.1),,,,,,,,Acidovorax citrulli,,Aac5,bacterial fruit blotch,eudicots,3654,Citrullus lanatus (related: wild melon),Ruixin,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37876782,PubMed,10.3389/fmicb.2023.1275032,Front Microbiol. 2023 Oct 9;14:1275032,yangyuwen@caas.cn,The deletion of aopU did not affect the virulence of A. citrulli.,L Yang 2023,2023,1 gene,Yang-2023-Acidovorax citrulli type III effecto,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22417,PHI:124405,UniProt,G2XHL4,GenBank,EGY19308,,,VdLs.17,Bre1 (VDAG_09768),chromosome 3,,,,,,27337,Verticillium dahliae,,v991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,Seedlings; stem,RING ubiquitin E3 ligase,,,lipid metabolism pathway,loss of pathogenicity,,,yes,,no lesion,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37888293,PubMed,10.3390/jof9101037,J Fungi (Basel). 2023 Oct 21;9(10):1037,20131913@cqnu.edu.cn,Knock out of VDAG_09768 mutant did not manifest any verticillium wilt symptoms compared to wild type.,X Yang 2023,2023,5 genes,Yang-2023-Functional Role of RING Ubiquitin E3,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22418,PHI:124406,UniProt,G2X3L2,GenBank,EGY23161,,,VdLs.17,Hrd1 (VDAG_04599),chromosome 3,,,,,,27337,Verticillium dahliae,,v991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,Seedlings; stem,RING ubiquitin E3 ligase,,,,loss of pathogenicity,,,yes,,no lesion,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37888293,PubMed,10.3390/jof9101037,J Fungi (Basel). 2023 Oct 21;9(10):1037,20131913@cqnu.edu.cn,Knock out of VDAG_04599 mutant did not manifest any verticillium wilt symptoms compared to wild type.,X Yang 2023,2023,5 genes,Yang-2023-Functional Role of RING Ubiquitin E3,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22419,PHI:124407,UniProt,G2XB62,GenBank,EGY16036,,,VdLs.17,VDAG_07200,chromosome 5,,,,,,27337,Verticillium dahliae,,v991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,Seedlings; stem,RING ubiquitin E3 ligase,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,37888293,PubMed,10.3390/jof9101037,J Fungi (Basel). 2023 Oct 21;9(10):1037,20131913@cqnu.edu.cn,Knock out of VDAG_07200 mutant showed reduced symptoms compared to wild type.,X Yang 2023,2023,5 genes,Yang-2023-Functional Role of RING Ubiquitin E3,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22420,PHI:124408,UniProt,G2XCL6,GenBank,EGY16734,,,VdLs.17,VDAG_07898,chromosome 2,,,,,,27337,Verticillium dahliae,,v991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,Seedlings; stem,RING ubiquitin E3 ligase,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,37888293,PubMed,10.3390/jof9101037,J Fungi (Basel). 2023 Oct 21;9(10):1037,20131913@cqnu.edu.cn,Knock out of VDAG_07898 mutant showed reduced symptoms compared to wild type.,X Yang 2023,2023,5 genes,Yang-2023-Functional Role of RING Ubiquitin E3,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22421,PHI:124409,UniProt,G2WS56,GenBank,EGY13707,,,VdLs.17,VDAG_00389,chromosome 2,,,,,,27337,Verticillium dahliae,,v991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,Seedlings; stem,RING ubiquitin E3 ligase,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,37888293,PubMed,10.3390/jof9101037,J Fungi (Basel). 2023 Oct 21;9(10):1037,20131913@cqnu.edu.cn,Knock out of VDAG_00389 mutant showed reduced symptoms compared to wild type.,X Yang 2023,2023,5 genes,Yang-2023-Functional Role of RING Ubiquitin E3,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22422,PHI:124410,UniProt,P21170,GenBank,AAA69105,,,K-12,speA (NP_417413.1),,,,,,,1778540,Dickeya fangzhongdai,,ZXC1,,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,arginine decarboxylase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Compared with the wild-type strain, the macerated zones of ΔA in potato was reduced by about 70%.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22423,PHI:124410,UniProt,P21170,GenBank,AAA69105,,,K-12,speA (NP_417413.1),,,,,,,1778540,Dickeya fangzhongdai,,ZXC1,,monocots,4460,Colocasia esculenta (related: taro),,,,Tubers,arginine decarboxylase,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Compared with the wild-type strain, the macerated zones of ΔA in trao was reduced by about 53%.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22424,PHI:124410,UniProt,P21170,GenBank,AAA69105,,,K-12,speA (NP_417413.1),,,,,,PHI:124411; PHI:124412,1778540,Dickeya fangzhongdai,,ZXC1,,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,arginine decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"The macerated zones of ΔAFP were reduced by about 80% compared to wild-type ZXC1, and complementation.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22425,PHI:124411,UniProt,A0A2K8QL65,GenBank,ATZ94243,,,DSM 101947,potF,,,,,,PHI:124410; PHI:124412,1778540,Dickeya fangzhongdai,,ZXC1,,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,putrescine-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"The macerated zones of ΔAFP were reduced by about 80% compared to wild-type ZXC1, and complementation.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22426,PHI:124412,UniProt,A0A2K8QMN2,GenBank,ATZ94305,,,DSM 101947,plaP,,,,,,PHI:124410; PHI:124411,1778540,Dickeya fangzhongdai,,ZXC1,,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,putrescine-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"The macerated zones of ΔAFP were reduced by about 80% compared to wild-type ZXC1, and complementation.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22427,PHI:124410,UniProt,P21170,GenBank,AAA69105,,,K-12,speA (NP_417413.1),,,,,,PHI:124411; PHI:124412,1778540,Dickeya fangzhongdai,,ZXC1,,monocots,4460,Colocasia esculenta (related: taro),,,,Tubers,arginine decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"The macerated zones of ΔAFP were reduced by about 58% compared to wild-type ZXC1, and complementation.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22428,PHI:124411,UniProt,A0A2K8QL65,GenBank,ATZ94243,,,DSM 101947,potF,,,,,,PHI:124410; PHI:124412,1778540,Dickeya fangzhongdai,,ZXC1,,monocots,4460,Colocasia esculenta (related: taro),,,,Tubers,putrescine-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"The macerated zones of ΔAFP were reduced by about 58% compared to wild-type ZXC1, and complementation.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22429,PHI:124412,UniProt,A0A2K8QMN2,GenBank,ATZ94305,,,DSM 101947,plaP,,,,,,PHI:124410; PHI:124411,1778540,Dickeya fangzhongdai,,ZXC1,,monocots,4460,Colocasia esculenta (related: taro),,,,Tubers,putrescine-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"The macerated zones of ΔAFP were reduced by about 58% compared to wild-type ZXC1, and complementation.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22430,PHI:124410,UniProt,P21170,GenBank,AAA69105,,,K-12,speA (NP_417413.1),,,,,,PHI:124413,1778540,Dickeya fangzhongdai,,ZXC1,,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,arginine decarboxylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Compared with the wild-type strain, the macerated zones of ΔAC in potato was reduced.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22431,PHI:124413,UniProt,P21169,GenBank,AAA66174,,,K-12,speC (NP_417440.4),,,,,,PHI:124410,1778540,Dickeya fangzhongdai,,ZXC1,,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,ornithine decarboxylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Compared with the wild-type strain, the macerated zones of ΔAC in potato was reduced.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22432,PHI:124410,UniProt,P21170,GenBank,AAA69105,,,K-12,speA (NP_417413.1),,,,,,PHI:124413,1778540,Dickeya fangzhongdai,,ZXC1,,monocots,4460,Colocasia esculenta (related: taro),,,,Tubers,arginine decarboxylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Compared with the wild-type strain, the macerated zones of ΔAC in taro was reduced.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22433,PHI:124413,UniProt,P21169,GenBank,AAA66174,,,K-12,speC (NP_417440.4),,,,,,PHI:124410,1778540,Dickeya fangzhongdai,,ZXC1,,monocots,4460,Colocasia esculenta (related: taro),,,,Tubers,ornithine decarboxylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Compared with the wild-type strain, the macerated zones of ΔAC in taro was reduced.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22434,PHI:124410,UniProt,P21170,GenBank,AAA69105,,,K-12,speA (NP_417413.1),,,,,,PHI:124411; PHI:124412; PHI:124413,1778540,Dickeya fangzhongdai,,ZXC1,,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,arginine decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Bacterial virulence of quadruple mutant ΔACFP was further reduced compared with the single-deletion mutant ΔA, double-deletion mutant ΔAC, and triple-deletion mutant ΔAFP.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22435,PHI:124411,UniProt,A0A2K8QL65,GenBank,ATZ94243,,,DSM 101947,potF,,,,,,PHI:124410; PHI:124412; PHI:124413,1778540,Dickeya fangzhongdai,,ZXC1,,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,putrescine-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Bacterial virulence of quadruple mutant ΔACFP was further reduced compared with the single-deletion mutant ΔA, double-deletion mutant ΔAC, and triple-deletion mutant ΔAFP.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22436,PHI:124412,UniProt,A0A2K8QMN2,GenBank,ATZ94305,,,DSM 101947,plaP,,,,,,PHI:124410; PHI:124411; PHI:124413,1778540,Dickeya fangzhongdai,,ZXC1,,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,putrescine-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Bacterial virulence of quadruple mutant ΔACFP was further reduced compared with the single-deletion mutant ΔA, double-deletion mutant ΔAC, and triple-deletion mutant ΔAFP.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22437,PHI:124413,UniProt,P21169,GenBank,AAA66174,,,K-12,speC (NP_417440.4),,,,,,PHI:124410; PHI:124411; PHI:124412,1778540,Dickeya fangzhongdai,,ZXC1,,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,ornithine decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Bacterial virulence of quadruple mutant ΔACFP was further reduced compared with the single-deletion mutant ΔA, double-deletion mutant ΔAC, and triple-deletion mutant ΔAFP.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22438,PHI:124410,UniProt,P21170,GenBank,AAA69105,,,K-12,speA (NP_417413.1),,,,,,PHI:124411; PHI:124412; PHI:124413,1778540,Dickeya fangzhongdai,,ZXC1,,monocots,4460,Colocasia esculenta (related: taro),,,,Tubers,arginine decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Bacterial virulence of quadruple mutant ΔACFP was further reduced compared with the single-deletion mutant ΔA, double-deletion mutant ΔAC, and triple-deletion mutant ΔAFP.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22439,PHI:124411,UniProt,A0A2K8QL65,GenBank,ATZ94243,,,DSM 101947,potF,,,,,,PHI:124410; PHI:124412; PHI:124413,1778540,Dickeya fangzhongdai,,ZXC1,,monocots,4460,Colocasia esculenta (related: taro),,,,Tubers,putrescine-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Bacterial virulence of quadruple mutant ΔACFP was further reduced compared with the single-deletion mutant ΔA, double-deletion mutant ΔAC, and triple-deletion mutant ΔAFP.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22440,PHI:124412,UniProt,A0A2K8QMN2,GenBank,ATZ94305,,,DSM 101947,plaP,,,,,,PHI:124410; PHI:124411; PHI:124413,1778540,Dickeya fangzhongdai,,ZXC1,,monocots,4460,Colocasia esculenta (related: taro),,,,Tubers,putrescine-binding periplasmic protein,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Bacterial virulence of quadruple mutant ΔACFP was further reduced compared with the single-deletion mutant ΔA, double-deletion mutant ΔAC, and triple-deletion mutant ΔAFP.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22441,PHI:124413,UniProt,P21169,GenBank,AAA66174,,,K-12,speC (NP_417440.4),,,,,,PHI:124410; PHI:124411; PHI:124412,1778540,Dickeya fangzhongdai,,ZXC1,,monocots,4460,Colocasia esculenta (related: taro),,,,Tubers,ornithine decarboxylase,,,,reduced virulence,,,,,,,,,,no,,,,,,,gene deletion: full,,,NN,37874149,PubMed,10.1128/spectrum.01965-23,Microbiol Spectr. 2023 Oct 24:e0196523,lhzhang01@scau.edu.cn,"Bacterial virulence of quadruple mutant ΔACFP was further reduced compared with the single-deletion mutant ΔA, double-deletion mutant ΔAC, and triple-deletion mutant ΔAFP.",C Xie 2023,2023,4 genes,xie-et-al-2023-polyamine-signaling-communicati,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22442,PHI:124414,UniProt,A0A0F7RX56,GenBank,CDR99848,,,,CCP1 (CDR99848.1),,,,,,,49012,Sporisorium scitamineum,,MAT-1 × MAT-2,sugarcane smut,monocots,4547,Saccharum officinarum (related: sugarcane),ROC22,,,Seedling,cytochrome c-peroxidase,,,Hog1-MAPK pathway,reduced virulence,,,,,reduced black whip symptom,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37819114,PubMed,10.1128/spectrum.02057-23,Microbiol Spectr. 2023 Oct 11:e0205723,changcq@scau.edu.cn,"Typical whip symptom in the ssccp1Δ strain-infected seedlings displayed significantly reduced pathogenicity, with only around 6.0% compared to wild type with 75% and complementory with 61%.",E Cai 2023,2023,1 gene,cai-et-al-2023-cytochrome-c-peroxidase-modulat,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22443,PHI:124415,UniProt,I6YDU0,GenBank,AFN66169,,,,CYP51A (FGSG_04092),,L16F; S35P,,,,,5518,Fusarium graminearum,,3-a,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,Coleoptiles,prothioconazole target protein-CYP51,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,increased,no,,,,,,,gene mutation,,,NN,37888257,PubMed,10.3390/jof9101001,J Fungi (Basel). 2023 Oct 10;9(10):1001.,liurunqiang1983@126.com,Prothioconazole-resistant mutants were found to exhibit a significant reduction in pathogenicity in comparison to their wild-type parental isolates.,F Zhou 2023,2023,3 genes,Zhou-2023-Exploring the Potential Mechanism of,,,MC,,,,,,,,,,,,,
,,Record 22444,PHI:124416,UniProt,B9UZF2,GenBank,ACL93395,,,,CYP51B(FGSG_01000),,P74T; F77L; G405S,,,,,5518,Fusarium graminearum,,3-a,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,Coleoptiles,prothioconazole target protein-CYP51,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,increased,no,,,,,,,gene mutation,,,NN,37888257,PubMed,10.3390/jof9101001,J Fungi (Basel). 2023 Oct 10;9(10):1001.,liurunqiang1983@126.com,Prothioconazole-resistant mutants were found to exhibit a significant reduction in pathogenicity in comparison to their wild-type parental isolates.,F Zhou 2023,2023,3 genes,Zhou-2023-Exploring the Potential Mechanism of,,,MC,,,,,,,,,,,,,
,,Record 22445,PHI:124416,UniProt,B9UZF2,GenBank,ACL93395,,,,CYP51B(FGSG_01000),,Y230F,,,,,5518,Fusarium graminearum,,4-a,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,Coleoptiles,prothioconazole target protein-CYP51,,,,reduced virulence,,,,,smaller lesions,increased,,increased,reduced,no,,,,,,,gene mutation,,,NN,37888257,PubMed,10.3390/jof9101001,J Fungi (Basel). 2023 Oct 10;9(10):1001.,liurunqiang1983@126.com,Prothioconazole-resistant mutants were found to exhibit a significant reduction in pathogenicity in comparison to their wild-type parental isolates.,F Zhou 2023,2023,3 genes,Zhou-2023-Exploring the Potential Mechanism of,,,MC,,,,,,,,,,,,,
,,Record 22446,PHI:124416,UniProt,B9UZF2,GenBank,ACL93395,,,,CYP51B(FGSG_01000),,Y37N; Q326R,,,,,5518,Fusarium graminearum,,SZ-1-3,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,Coleoptiles,prothioconazole target protein-CYP51,,,,reduced virulence,,,,,smaller lesions,increased,,increased,reduced,no,,,,,,,gene mutation,,,NN,37888257,PubMed,10.3390/jof9101001,J Fungi (Basel). 2023 Oct 10;9(10):1001.,liurunqiang1983@126.com,Prothioconazole-resistant mutants were found to exhibit a significant reduction in pathogenicity in comparison to their wild-type parental isolates.,F Zhou 2023,2023,3 genes,Zhou-2023-Exploring the Potential Mechanism of,,,MC,,,,,,,,,,,,,
,,Record 22447,PHI:124417,UniProt,A0A9N8WT97,GenBank,CAG1984980,,,,CYP51C (FGSG_11024),,E164K; I191T; S256A; M273L; V424E,,,,,5518,Fusarium graminearum,,3-a,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,Coleoptiles,prothioconazole target protein-CYP51,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,increased,no,,,,,,,gene mutation,,,NN,37888257,PubMed,10.3390/jof9101001,J Fungi (Basel). 2023 Oct 10;9(10):1001.,liurunqiang1983@126.com,Prothioconazole-resistant mutants were found to exhibit a significant reduction in pathogenicity in comparison to their wild-type parental isolates.,F Zhou 2023,2023,3 genes,Zhou-2023-Exploring the Potential Mechanism of,,,MC,,,,,,,,,,,,,
,,Record 22448,PHI:124417,UniProt,A0A9N8WT97,GenBank,CAG1984980,,,,CYP51C (FGSG_11024),,V307A,,,,,5518,Fusarium graminearum,,4-a,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,Coleoptiles,prothioconazole target protein-CYP51,,,,reduced virulence,,,,,smaller lesions,increased,,increased,reduced,no,,,,,,,gene mutation,,,NN,37888257,PubMed,10.3390/jof9101001,J Fungi (Basel). 2023 Oct 10;9(10):1001.,liurunqiang1983@126.com,Prothioconazole-resistant mutants were found to exhibit a significant reduction in pathogenicity in comparison to their wild-type parental isolates.,F Zhou 2023,2023,3 genes,Zhou-2023-Exploring the Potential Mechanism of,,,MC,,,,,,,,,,,,,
,,Record 22449,PHI:124418,UniProt,G4N3X3,GenBank,EHA52746,,,70-15,ABC-R1 (MGG_05044),chromosome 3,,,,,,318829,Magnaporthe oryzae,,YN226,rice blast,monocots,4530,Oryza sativa (related: rice),Nipponbare,,,Leaves,ABCC-type transporter,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,NaCl;KCl,NaCl: CHEBI:26710; ;KCl: CHEBI:32588,,,,,gene deletion: full ; gene complementation,,,NN,37755025,PubMed,10.3390/jof9090917,J Fungi (Basel). 2023 Sep 11;9(9):917,kanghouxiang@caas.cn,Disease lesions caused by the abc-r1 were smaller compared to the wild-type strain YN226.,P Hu 2023,2023,1 gene,Hu-2023-ABCC Transporter Gene MoABC-R1 Is Asso,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22450,PHI:124419,UniProt,G2XIC7,GenBank,EGY19575,,,VdLs.17,PKC (VDAG_09909),chromosome 1,,,,,,27337,Verticillium dahliae,,JY,vascular wilt,eudicots,4113,Solanum tuberosum (related: potato),,,,Seedlings; stem,protein kinase C,,,ca2+ signaling pathway,reduced virulence,,,yes,,no visible disease,reduced,,reduced,reduced,no,sorbitol;NaCl;sucrose;fludioxonil;polyethylene glycol (PEG-8000);prochloraz;difenoconazole (DCZ);glucose;Congo red;calcofluor white (CFW);calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;sucrose: CHEBI:17992; ;fludioxonil: CHEBI:81763; ;polyethylene glycol (PEG-8000): CHEBI:46793; ;prochloraz: CHEBI:8434; ;difenoconazole (DCZ): CHEBI:81760; ;glucose: CHEBI:17234; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,37762573,PubMed,10.3390/ijms241814266,Int J Mol Sci. 2023 Sep 19;24(18):14266,rfan@gzu.edu.cn,The disease index with ΔVdPKC was significantly lower than that of the WT and mutant ΔVdPKC-C.,D Wang 2023,2023,1 gene,Wang-2023-Protein Kinase C Is Involved in Vege,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22451,PHI:124420,UniProt,A0A2H3G1R9,GenBank,CAG2008002,,,MDC_Fg202,Eps1 (FGSG_06174),,,,,,,5518,Fusarium graminearum,229533,PH-1 (NRRL 31084),Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Xiaoyan 22,,,spikelets,protein disulfide isomerase,,,,reduced virulence,,,yes,,smaller lesions,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2);CaCl2;NaCl;MgCl2;CuSO4;KCl;caffeine;sodium dodecyl sulphate (SDS);tebuconazole;phenamacril;Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;MgCl2: CHEBI:6636; ;CuSO4: CHEBI:23414; ;KCl: CHEBI:32588; ;caffeine: CHEBI:27732; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;tebuconazole: CHEBI:81781; ;phenamacril CAS no.: CAS:3336-69-4; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,37888265,PubMed,10.3390/jof9101009,J Fungi (Basel). 2023 Oct 12;9(10):1009,pengcheng@nwafu.edu.cn,"ΔEps1 mutation affected nutritional growth, asexual and sexual reproduction, stress tolerance and reduced pathogenicity.",K Liu 2023,2023,1 gene,Liu-2023-Protein Disulfide Isomerase FgEps1 Is,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22452,PHI:124420,UniProt,A0A2H3G1R9,GenBank,CAG2008002,,,MDC_Fg202,Eps1 (FGSG_06174),,,,,,,5518,Fusarium graminearum,229533,PH-1 (NRRL 31084),Fusarium head blight,monocots,4577,Zea mays (related: maize),,,,maize silk,protein disulfide isomerase,,,,reduced virulence,,,yes,,smaller lesions,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2);CaCl2;NaCl;MgCl2;CuSO4;KCl;caffeine;sodium dodecyl sulphate (SDS);tebuconazole;phenamacril;Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;MgCl2: CHEBI:6636; ;CuSO4: CHEBI:23414; ;KCl: CHEBI:32588; ;caffeine: CHEBI:27732; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;tebuconazole: CHEBI:81781; ;phenamacril CAS no.: CAS:3336-69-4; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,37888265,PubMed,10.3390/jof9101009,J Fungi (Basel). 2023 Oct 12;9(10):1009,pengcheng@nwafu.edu.cn,"ΔEps1 mutation affected nutritional growth, asexual and sexual reproduction, stress tolerance and reduced pathogenicity.",K Liu 2023,2023,1 gene,Liu-2023-Protein Disulfide Isomerase FgEps1 Is,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22453,PHI:124421,UniProt,A0A177DCY5,GenBank,OAG16982,,,SRC1lrK2f,stuA,chromosome unknown,,,PacC,UniProt: A0A177DU84; GenBank: OAG23048,,5599,Alternaria alternata,,Z7,brown spot disease,eudicots,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,APSES transcription factor,,,ACT pathway,loss of pathogenicity,,,,,no necrotic lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37812002,PubMed,10.1128/spectrum.02335-23,Microbiol Spectr. 2023 Oct 9:e0233523,hyli@zju.edu.cn,No necrosis was observed on leaves inoculated with ΔstuA 3 dpi compared with wild type and complementary mutant.,Y Chen 2023,2023,2 genes,chen-et-al-2023-the-alternaria-alternata-stua-,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22454,PHI:124422,UniProt,A0A177DU84,GenBank,OAG23048,,,SRC1lrK2f,pacC,chromosome unknown,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicots,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,transcription factor,,,ACT pathway,reduced virulence,,,,,smaller necrotic lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37812002,PubMed,10.1128/spectrum.02335-23,Microbiol Spectr. 2023 Oct 9:e0233523,hyli@zju.edu.cn,Virulence assays on Hongjv leaves showed that the pacC mutant induced much smaller necrotic lesions than the wild type.,Y Chen 2023,2023,2 genes,chen-et-al-2023-the-alternaria-alternata-stua-,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22455,PHI:124423,UniProt,A0A1D9QG82,GenBank,APA13918,,,1980,Gap1 (sscle_12g086880),chromosome 12,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,Ras-GAP domain-containing protein,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,"Knockout mutant displayed reduced colony morphology, vegetative growth and virulence when compared with wild type both in wounded and unwounded leaves.",Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22456,PHI:124423,UniProt,A0A1D9QG82,GenBank,APA13918,,,1980,Gap1 (sscle_12g086880),chromosome 12,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,Ras-GAP domain-containing protein,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,"Knockout mutant displayed reduced colony morphology, vegetative growth and virulence when compared with wild type both in wounded and unwounded leaves.",Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22457,PHI:124424,UniProt,A0A384JLY5,GenBank,ATZ51374,,,B05.10,Gap1 (XP_001555983),chromosome BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,Ras-GAP domain-containing protein,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,Bcgap1 mutants did not exhibit significant growth defects compared to B. cinerea WT strain B05.10 and significantly reduced lesions.,Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22458,PHI:124424,UniProt,A0A384JLY5,GenBank,ATZ51374,,,B05.10,Gap1 (XP_001555983),chromosome BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,29760,Vitis vinifera (related: wine grape),,,,Leaves,Ras-GAP domain-containing protein,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,Bcgap1 mutants did not exhibit significant growth defects compared to B. cinerea WT strain B05.10 and significantly reduced lesions.,Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22459,PHI:124425,UniProt,A0A1D9QE66,GenBank,APA13254,,,1980,RAS1 (Sscle10g080240),chromosome 10,,,Gap1,UniProt: A0A1D9QG82; GenBank: APA13918,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,RAS-like GTPases,,,,reduced virulence,,,,,smaller lesions,increased,,reduced,,no,,,,,,,gene deletion: full,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,"Knockout mutant displayed reduced colony morphology, vegetative growth and virulence when compared with wild type in unwounded leaves.",Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22460,PHI:124425,UniProt,A0A1D9QE66,GenBank,APA13254,,,1980,RAS1 (Sscle10g080240),chromosome 10,,,Gap1,UniProt: A0A1D9QG82; GenBank: APA13918,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,RAS-like GTPases,,,,reduced virulence,,,,,smaller lesions,increased,,reduced,,no,,,,,,,gene deletion: full,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,"Knockout mutant displayed reduced colony morphology, vegetative growth and virulence when compared with wild type in unwounded leaves.",Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22461,PHI:124426,UniProt,A0A1D9QC82,GenBank,APA12521,,,1980,RAS2 (Sscle09g072910),chromosome 9,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,RAS-like GTPases,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,"Knockout mutant displayed reduced colony morphology, vegetative growth and virulence when compared with wild type in unwounded leaves.",Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22462,PHI:124426,UniProt,A0A1D9QC82,GenBank,APA12521,,,1980,RAS2 (Sscle09g072910),chromosome 9,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,RAS-like GTPases,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,"Knockout mutant displayed reduced colony morphology, vegetative growth and virulence when compared with wild type in unwounded leaves.",Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22463,PHI:124423,UniProt,A0A1D9QG82,GenBank,APA13918,,,1980,Gap1 (sscle_12g086880),chromosome 12,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,Ras-GAP domain-containing protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,Silencing of Gap1 resulted in reduced virulence.,Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22464,PHI:124423,UniProt,A0A1D9QG82,GenBank,APA13918,,,1980,Gap1 (sscle_12g086880),chromosome 12,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,Ras-GAP domain-containing protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,Silencing of Gap1 resulted in reduced virulence.,Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22465,PHI:124423,UniProt,A0A1D9QG82,GenBank,APA13918,,,1980,Gap1 (sscle_12g086880),chromosome 12,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,Ras-GAP domain-containing protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,Silencing of Gap1 resulted in reduced virulence.,Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22466,PHI:124425,UniProt,A0A1D9QE66,GenBank,APA13254,,,1980,RAS1 (Sscle10g080240),chromosome 10,,,Gap1,UniProt: A0A1D9QG82; GenBank: APA13918,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,RAS-like GTPases,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,Silencing of RAS1 resulted in reduced virulence.,Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22467,PHI:124426,UniProt,A0A1D9QC82,GenBank,APA12521,,,1980,RAS2 (Sscle09g072910),chromosome 9,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,RAS-like GTPases,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,37845842,PubMed,10.1111/pbi.14184,Plant Biotechnol J. 2023 Oct 16. doi: 10.1111/pbi.14184. Online ahead of print,yuelin.zhang@scu,Silencing of RAS2 resulted in reduced virulence.,Y Xu 2023,2023,4 genes,Xu et al 2023- RAS signalling genes can be use,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22468,PHI:124427,UniProt,A0A0F7S254,GenBank,CDU25136,,,SscI8,AGA (SPSC_04970),,,,,,,49012,Sporisorium scitamineum,,MAT-1 × MAT-2,sugarcane smut,monocots,4547,Saccharum officinarum (related: sugarcane),ROC22,,,Seedlings,putative arginase,,,polyamine biosynthesis pathway,loss of pathogenicity,,,,,no symptom,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37814404,PubMed,10.1111/mpp.13393,Mol Plant Pathol. 2023 Oct 9,dengyz@scau.edu.cn,No black whip symptom was found in the seedlings infected by ss1agaΔ × ss2agaΔ.,K Yin 2023,2023,3 genes,Yin et al 2023 - Intracellular polyamines regu,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22469,PHI:124428,UniProt,A0A0F7RSM2,GenBank,CDU24605,,,SscI8,ODC (SPSC_04106),,,,,,,49012,Sporisorium scitamineum,,MAT-1 × MAT-2,sugarcane smut,monocots,4547,Saccharum officinarum (related: sugarcane),ROC22,,,Seedlings,ornithine decarboxylase,,,polyamine biosynthesis pathway,loss of pathogenicity,,,,,no symptom,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37814404,PubMed,10.1111/mpp.13393,Mol Plant Pathol. 2023 Oct 9,dengyz@scau.edu.cn,No black whip symptom was found in the seedlings infected by ss1odcΔ × ss2odcΔ.,K Yin 2023,2023,3 genes,Yin et al 2023 - Intracellular polyamines regu,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22470,PHI:124429,UniProt,A0A0F7RSB2,GenBank,CDU24548,,,SscI8,SAMDC (SPSC_04049),,,,,,,49012,Sporisorium scitamineum,,MAT-1 × MAT-2,sugarcane smut,monocots,4547,Saccharum officinarum (related: sugarcane),ROC22,,,Seedlings,S-adenosylmethionine decarboxylase,,,polyamine biosynthesis pathway,loss of pathogenicity,,,,,no symptom,,,reduced,,no,,,,,,,gene deletion: full,,,NN,37814404,PubMed,10.1111/mpp.13393,Mol Plant Pathol. 2023 Oct 9,dengyz@scau.edu.cn,No black whip symptom was found in the seedlings infected by ss1samdcΔ × ss2samdcΔ.,K Yin 2023,2023,3 genes,Yin et al 2023 - Intracellular polyamines regu,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22471,PHI:124430,UniProt,A0A384JN58,GenBank,ATZ51942,,,B05.10,Crh4 (Bcin07g04870),chromosome BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3764,Rosa (no common name found),,,,Petal,transglycosylase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,37846876,PubMed,10.1111/pce.14740,Plant Cell Environ. 2023 Oct 17,amirsh@tauex.tau.ac.il,"Δbccrh4 strains caused significantly smaller lesions than the wild-type strain on highly sensitive tissues, such as rose petals.",Y Liang 2023,2023,1 gene,Liang et al 2023 - The Botrytis cinerea transg,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22472,PHI:124430,UniProt,A0A384JN58,GenBank,ATZ51942,,,B05.10,Crh4 (Bcin07g04870),chromosome BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,4081,Solanum lycopersicum (related: tomato),,,,Leaves; fruit,transglycosylase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,37846876,PubMed,10.1111/pce.14740,Plant Cell Environ. 2023 Oct 17,amirsh@tauex.tau.ac.il,The Δbccrh4 strains caused reduced symptoms in tomato leaves and fruit.,Y Liang 2023,2023,1 gene,Liang et al 2023 - The Botrytis cinerea transg,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22473,PHI:124430,UniProt,A0A384JN58,GenBank,ATZ51942,,,B05.10,Crh4 (Bcin07g04870),chromosome BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3885,Phaseolus vulgaris (related: string bean),,,,Leaves,transglycosylase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,37846876,PubMed,10.1111/pce.14740,Plant Cell Environ. 2023 Oct 17,amirsh@tauex.tau.ac.il,The Δbccrh4 strains caused reduced symptoms in bean leaves.,Y Liang 2023,2023,1 gene,Liang et al 2023 - The Botrytis cinerea transg,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22474,PHI:124430,UniProt,A0A384JN58,GenBank,ATZ51942,,,B05.10,Crh4 (Bcin07g04870),chromosome BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,4236,Lactuca sativa (related: garden lettuce),,,,Leaves,transglycosylase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,37846876,PubMed,10.1111/pce.14740,Plant Cell Environ. 2023 Oct 17,amirsh@tauex.tau.ac.il,"Δbccrh4 strains caused significantly smaller lesions than the wild-type strain on highly sensitive tissues, such as lettuce.",Y Liang 2023,2023,1 gene,Liang et al 2023 - The Botrytis cinerea transg,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22475,PHI:124430,UniProt,A0A384JN58,GenBank,ATZ51942,,,B05.10,Crh4 (Bcin07g04870),chromosome BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,Leaves,transglycosylase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,37846876,PubMed,10.1111/pce.14740,Plant Cell Environ. 2023 Oct 17,amirsh@tauex.tau.ac.il,Δbccrh4 strains caused significantly smaller lesions than the wild-type strain on less sensitive Arabidopsis leaves.,Y Liang 2023,2023,1 gene,Liang et al 2023 - The Botrytis cinerea transg,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22476,PHI:124430,UniProt,A0A384JN58,GenBank,ATZ51942,,,B05.10,Crh4 (Bcin07g04870),chromosome BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,monocot,3702,Arabidopsis thaliana (related: thale cress),,,,Leaves,transglycosylase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,37846876,PubMed,10.1111/pce.14740,Plant Cell Environ. 2023 Oct 17,amirsh@tauex.tau.ac.il,Δbccrh4 strains caused significantly smaller lesions than the wild-type strain on maize leaves.,Y Liang 2023,2023,1 gene,Liang et al 2023 - The Botrytis cinerea transg,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22477,PHI:124431,UniProt,A0A194VEB1,GenBank,KUI62223,,,SXYL134,Veb1 (A0A194VEB1),chromosome unknown,,,,,,694573,Valsa pyri,,Vp297,Valsa canker,eudicots,23211,Pyrus communis (related: pear),Su Cui No.1,,,Twigs,AAA+ ATPase domain-containing protein,,,,reduced virulence,,,yes,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37812568,PubMed,10.1021/acs.jafc.3c06262,J Agric Food Chem. 2023 Oct 18;71(41):15003-15016,fqliu20011@sina.com,"Twigs inoculated with ΔVpVEB1 were significantly attenuated, and the average length of the lesion was 0.77 ± 0.308 cm where wild type average length of lesion was 3.18 ± 0.195 cm.",R Hou 2023,2023,1 gene,hou-et-al-2023-antifungal-compound-from-the-pr,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22478,PHI:124431,UniProt,A0A194VEB1,GenBank,KUI62223,,,SXYL134,Veb1 (A0A194VEB1),chromosome unknown,VEB1T569A/G570A,,,,,694573,Valsa pyri,,Vp297,Valsa canker,eudicots,23211,Pyrus communis (related: pear),Su Cui No.1,,,Twigs,AAA+ ATPase domain-containing protein,,,,reduced virulence,,,yes,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37812568,PubMed,10.1021/acs.jafc.3c06262,J Agric Food Chem. 2023 Oct 18;71(41):15003-15016,fqliu20011@sina.com,Twigs inoculated with ΔVpVEB1T569A/G570A was significantly reduced virulence compared to wild type.,R Hou 2023,2023,1 gene,hou-et-al-2023-antifungal-compound-from-the-pr,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22479,PHI:124432,UniProt,A0A0J9WVB5,GenBank,KNB19241,,,4287,SIX5 (FOXG_22493),chromosome 14,,,,,,5507,Fusarium oxysporum,,007,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),C32,,,Seedlings,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37782126,PubMed,10.1094/MPMI-07-23-0103-FI,Mol Plant Microbe Interact. 2023 Oct 2,F.L.W.Takken@uva.nl,Plants showed reduced disease symptoms as well as increased fresh weight of the plants as compared to plants inoculated with the WT.,N Talbi 2023,2023,1 gene,Talbi et al 2023 mpmi-07-23-0103-fi,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22480,PHI:124433,UniProt,Q9XC86,GenBank,AAD44807,,,,Fur (AF146830),,,,,,,347,Xanthomonas oryzae,360094,pv. oryzae PXO99A,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24,,,leaves,ferric uptake regulator,,,cellular regulatory pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,37831462,PubMed,10.1128/spectrum.01187-23,Microbiol Spectr. 2023 Oct 13:e0118723,fqliu20011@sina.com,Infection of Δxanfur in rice leaf was significantly lower than that of WT or CpΔxanfur in rice leaf 7 and 14 days post-inoculation.,Y Q Zhang 2023,2023,1 gene,zhang-et-al-2023-xanfur-a-novel-fur-protein-in,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22481,PHI:124434,UniProt,A0A8H4N345,GenBank,KAF4302389,,,sdau11-99,Hog1,,,,,,,55169,Botryosphaeria dothidea,,LW03,botryosphaeria canker and apple ring rot,eudicots,3750,Malus domestica (related: apple),Fuji,,,Fruits; stem; Leaves,mitogen-activated protein kinase,,,HOG-MAPK pathway,reduced virulence,,,,,,reduced,,increased,,no,sorbitol;NaCl;KCl,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588,,,,,gene deletion: full ; gene complementation,,,NN,37889135,PubMed,10.1094/PHYTO-07-23-0260-R,Phytopathology. 2023 Oct 27,liunalz@163.com,Lesions on fruits and branches of ΔBdHog1 were significantly smaller than those caused by wild-type LW03 and ΔBdHog1-C.,Y Zhang 2023,2023,1 gene,Zhang et al 2023 phyto-07-23-0260-r,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22482,PHI:124435,UniProt,A0A0K1ZHU9,GenBank,CUV17476,,,Phyl III-seqv23,PhcX (WP_011002641.1),chromosome III,,,,,,305,Ralstonia solanacearum,,EP1,bacterial wilt,eudicot,4081,Solanum lycopersicum (related: tomato),Zhongshusihao,,,leaves,lqsR-family response regulator,,,phc QS pathway,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37787568,PubMed,10.1128/mbio.02028-23,mBio. 2023 Oct 3:e0202823,bio_lip@hainnu.edu.cn,"All the plants inoculated with wild-type EP1 died within 2 weeks, whereas 12.5% and 44% of the plants inoculated with ΔphcX survived in the stem injection and root dipping assays.",Q Liu 2023,2023,1 gene,liu-et-al-2023-phcx-is-a-lqsr-family-response-,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22483,PHI:124436,UniProt,A0A0J9W549,GenBank,KNB17988,,,4287,Doa1 (FOXG_15663),chromosome 8,,,,,,5507,Fusarium oxysporum,120297,f.sp. Niveum race 1 (ZJ1),Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),Zaojia,,,Seedlings,ubiquitin−proteasome system,,,,reduced virulence,,,yes,,low disease severity,reduced,,reduced,reduced,no,fluconazole;hydrogen peroxide (H2O2);caspofungin;NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),fluconazole: CHEBI:46081; ;hydrogen peroxide (H2O2): CHEBI:16240; ;caspofungin: CHEBI:474180; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,37486296,PubMed,10.1021/acs.jafc.3c01785,J Agric Food Chem. 2023 Aug 2;71(30):11667-11679.,dyli@zju.edu.cn,ΔFondoa1 inoculated plants showed delayed appearance of disease symptoms and a significant reduction in disease severity indexes (∼40) compared to WT- (∼82) and complementation strain (∼71)- inoculated plants.,M Noman 2023,2023,2 genes,noman-et-al-2023-degradation-of-?-subunits-doa,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22484,PHI:124437,UniProt,A0A0J9UD20,GenBank,KNB17988,,,4287,Doa4 (FOXG_01907),chromosome 5,,,,,,5507,Fusarium oxysporum,120297,f.sp. Niveum race 1 (ZJ1),Fusarium wilt,eudicots,3654,Citrullus lanatus (related: wild melon),Zaojia,,,Seedlings,ubiquitin−proteasome system,,,,reduced virulence,,,yes,,low disease severity,reduced,,reduced,reduced,no,fluconazole;hydrogen peroxide (H2O2);caspofungin;NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),fluconazole: CHEBI:46081; ;hydrogen peroxide (H2O2): CHEBI:16240; ;caspofungin: CHEBI:474180; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,37486296,PubMed,10.1021/acs.jafc.3c01785,J Agric Food Chem. 2023 Aug 2;71(30):11667-11679.,dyli@zju.edu.cn,ΔFondoa4 inoculated plants showed delayed appearance of disease symptoms and a significant reduction in disease severity indexes (∼58) compared to WT- (∼82) and complementation strain (∼74)- inoculated plants.,M Noman 2023,2023,2 genes,noman-et-al-2023-degradation-of-?-subunits-doa,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22485,PHI:124438,UniProt,X0JUH8,GenBank,EXM04939,,,54006,SPC2 (FOIG_05064),chromosome unknown,,,,,,2502994,Fusarium odoratissimum,,58,,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish (AAA),,,Leaves; Corm,SPase complex,,,,reduced virulence,,,yes,,smaller necrotic lesions,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,37367437,PubMed,10.1128/spectrum.04403-22,Microbiol Spectr. 2023 Aug 17;11(4):e0440322.,dengyz@scau.edu.cn,"FoSPC2 deletion caused defects in vegetative growth, conidiation, and virulence.",S Yang 2023,2023,1 gene,Yang-2023-The Signal Peptidase FoSpc2 Is Requi,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22486,PHI:124439,UniProt,P52698,GenBank,AAC36989,,,AW1,phcA,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicot,4081,Solanum lycopersicum (related: tomato),Ohgata-Fukuju,,,Seedlings; Roots,transcription regulator,,,,loss of pathogenicity,,,,,no symptoms,,,increased,,no,,,,,,,gene deletion: full,,,NN,37452484,PubMed,10.1111/mpp.13374,Mol Plant Pathol. 2023 Nov;24(11):1370-1384.,yhikichi@kochi-u.ac.jp,The plants inoculated with OE1-1 exhibited wilt symptoms at 5 days after inoculation (DAI) and died by 9 DAI whereas ΔphcA was not virulent on tomato plants.,C Takemura 2023,2023,1 gene,Takemura-2023-The transcription regulator ChpA,BATCH_127A,2023-11-01,MC,,,,,,,,,,,,,
,,Record 22487,PHI:124440,UniProt,I1RL06,GenBank,ESU08505,,,PH-1,Abc1 (FGSG_04580),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,ABC transporter,,,,reduced virulence,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Abc1 reduced FHB spread by ~78% compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22488,PHI:124441,UniProt,I1S2M9,GenBank,CEF87564,,,PH-1,Abc6 (FGSG_11028),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,ABC transporter,,,,reduced virulence,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Abc1 reduced FHB spread by ~30% compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22489,PHI:124442,UniProt,A0A346JIK4,GenBank,AXP33437,,,04501,Tril2 (FGSG_03541),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,trichothecene biosynthetic gene,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Tril2 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22490,PHI:124443,UniProt,I1RUB5,GenBank,CEF84171,,,04501,Mfs1(FGSG_07802),,chromosome 4,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,MFS transporter,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Mfs1 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22491,PHI:124440,UniProt,I1RL06,GenBank,ESU08505,,,PH-1,Abc1 (FGSG_04580),chromosome 2,,,,,PHI:124442,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,ABC transporter,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Abc1/Tril2 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22492,PHI:124442,UniProt,A0A346JIK4,GenBank,AXP33437,,,04501,Tril2 (FGSG_03541),,,,,,PHI:124440,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,trichothecene biosynthetic gene,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Abc1/Tril2 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22493,PHI:124443,UniProt,I1RUB5,GenBank,CEF84171,,,04501,Mfs1(FGSG_07802),,chromosome 4,,,,PHI:124442,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,MFS transporter,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Mfs1/Tril2 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22494,PHI:124442,UniProt,A0A346JIK4,GenBank,AXP33437,,,04501,Tril2 (FGSG_03541),,,,,,PHI:124443,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,trichothecene biosynthetic gene,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Mfs1/Tril2 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22495,PHI:124441,UniProt,I1S2M9,GenBank,CEF87564,,,PH-1,Abc6 (FGSG_11028),chromosome 3,,,,,PHI:124442,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,ABC transporter,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Abc6/Tril2 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22496,PHI:124442,UniProt,A0A346JIK4,GenBank,AXP33437,,,04501,Tril2 (FGSG_03541),,,,,,PHI:124441,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,trichothecene biosynthetic gene,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Abc6/Tril2 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22497,PHI:124443,UniProt,I1RUB5,GenBank,CEF84171,,,04501,Mfs1(FGSG_07802),,chromosome 4,,,,PHI:124441; PHI:124442,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,MFS transporter,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Mfs1/Tril2/Abc6 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22498,PHI:124442,UniProt,A0A346JIK4,GenBank,AXP33437,,,04501,Tril2 (FGSG_03541),,,,,,PHI:124441; PHI:124443,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,trichothecene biosynthetic gene,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Mfs1/Tril2/Abc6 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22499,PHI:124441,UniProt,I1S2M9,GenBank,CEF87564,,,PH-1,Abc6 (FGSG_11028),chromosome 3,,,,,PHI:124442; PHI:124443,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,ABC transporter,,,,unaffected pathogenicity,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,37260101,PubMed,10.1094/PHYTO-09-22-0345-R,Phytopathology. 2023 Oct;113(10):1916-1923.,mitch.elmore@usda.gov,Deletion of Mfs1/Tril2/Abc6 did not significantly reduced FHB symptoms compared to wild type.,S P O Mara 2023,2023,4 genes,O'Mara et al 2023 phyto-09-22-0345-r,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22500,PHI:124444,UniProt,G4NCN0,GenBank,EHA49124,,,70-15,CDC25 (MGG_00371),chromosome 5,,,Scd1 (MGG_09697); Mst50,UniProt: G4NAK1; GenBank: EHA51339; UniProt: G4N525; GenBank: EHA52936,,318829,Magnaporthe oryzae,,Guy11 (ΔKu80),rice blast,monocots,4513,Hordeum vulgare (related: barley),Golden Promise,,,Leaves,Ras guanine nucleotide exchange factor gene,,,MAPK and cAMP-PKA pathway,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,37460083,PubMed,10.1016/j.fgb.2023.103825,Fungal Genet Biol. 2023 Oct;168:103825.,zhywang@zju.edu.cn,No lesions were produced by the ΔMocdc25 mutant in both wounded and unwounded barley leaves.,Y Xiao 2023,2023,1 gene,Xiao et al 2023 1-s2.0-S1087184523000567-main,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22501,PHI:124444,UniProt,G4NCN0,GenBank,EHA49124,,,70-15,CDC25 (MGG_00371),chromosome 5,,,Scd1 (MGG_09697); Mst50,UniProt: G4NAK1; GenBank: EHA51339; UniProt: G4N525; GenBank: EHA52936,,318829,Magnaporthe oryzae,,Guy11 (ΔKu80),rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,Ras guanine nucleotide exchange factor gene,,,MAPK and cAMP-PKA pathway,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,37460083,PubMed,10.1016/j.fgb.2023.103825,Fungal Genet Biol. 2023 Oct;168:103825.,zhywang@zju.edu.cn,"By 5 dpi, the Ku80 strain and the complemented CΔMocdc25 caused numerous typical spreading lesions on rice leaves, while no obvious lesions were observed on the rice leaves inoculated by the ΔMocdc25 mutant.",Y Xiao 2023,2023,1 gene,Xiao et al 2023 1-s2.0-S1087184523000567-main,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22502,PHI:124445,UniProt,G4N2N1,GenBank,EHA52536,,,70-15,Cand2 (MGG_04863),chromosome 3,,,MoCullin1 (MGG_07145); MoCullin3 (MGG_07731); MoCullin4B (MGG_14763),UniProt: G4MT70; GenBank: EHA55535; UniProt: G4N0J9; GenBank: EHA53130; UniProt: G4MVM2; Gen,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),,,,Leaves,cullin-associated NEDD8-dissociated protein 2,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);paraquat;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;paraquat: CHEBI:34905; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,37718510,PubMed,10.1016/j.xplc.2023.100720,Plant Commun. 2023 Sep 16:100720.,fuchenglin@zju.edu.cn,"Mocand2 knockout resulted in defects in growth, conidiation, stress resistance, and pathogenicity.",Y Zhang 2023,2023,1 gene,Zhang et al 2023 1-s2.0-S2590346223002663-main,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22503,PHI:124445,UniProt,G4N2N1,GenBank,EHA52536,,,70-15,Cand2 (MGG_04863),chromosome 3,ΔMocand2Tip120,,MoCullin1 (MGG_07145); MoCullin3 (MGG_07731); MoCullin4B (MGG_14763),UniProt: G4MT70; GenBank: EHA55535; UniProt: G4N0J9; GenBank: EHA53130; UniProt: G4MVM2; Gen,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),,,,Leaves,cullin-associated NEDD8-dissociated protein 2,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);paraquat;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;paraquat: CHEBI:34905; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,37718510,PubMed,10.1016/j.xplc.2023.100720,Plant Commun. 2023 Sep 16:100720.,fuchenglin@zju.edu.cn,"Mocand2Tip120 knockout failed to infect the leaves, whereas Guy11 and the complementation strain produced obvious lesions at 96 h post inoculation",Y Zhang 2023,2023,1 gene,Zhang et al 2023 1-s2.0-S2590346223002663-main,BATCH_127B,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22504,PHI:124446,UniProt,G4MNL2,GenBank,EHA57918,,,70-15,Emc5 (MGG_05640),chromosome 1,,,Emc2 (MGG_07480),UniProt: G4N1A1; GenBank: EHA51580,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,3750,Malus domestica (related: apple),Lijiangxintuanheigu,,,Leaves,ER membrane complex,,,,reduced virulence,,,yes,,smaller lesions,wild type,,wild type,,no,sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36772852,PubMed,10.3390/foods12030479,Foods. 2023 Jan 19;12(3):479,luxunli@cau.edu.cn,The lesion numbers per 2 cm2 leaf and the relative lesion area caused by ΔMoemc5 mutant were significantly less than those by WT P131 and cMoEMC5.,Liu 2023,2023,1 gene,NewPhytologist-2023-Liu,BACTH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22505,PHI:124446,UniProt,G4MNL2,GenBank,EHA57918,,,70-15,Emc5 (MGG_05640),chromosome 1,,,Emc2 (MGG_07480),UniProt: G4N1A1; GenBank: EHA51580,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4513,Hordeum vulgare (related: barley),E9,,,Leaves,ER membrane complex,,,,reduced virulence,,,yes,,smaller lesions,wild type,,wild type,,no,sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36772852,PubMed,10.3390/foods12030479,Foods. 2023 Jan 19;12(3):479,luxunli@cau.edu.cn,The lesion numbers per 2 cm2 leaf and the relative lesion area caused by ΔMoemc5 mutant were significantly less than those by WT P131 and cMoEMC5.,Liu 2023,2023,1 gene,NewPhytologist-2023-Liu,BACTH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22506,PHI:124447,UniProt,A0A0A2I2M6,GenBank,KGO49358,,,MD-8,clg (PEX2_031290),,,,,,,27334,Penicillium expansum,,3.3703,blue mold,eudicots,3750,Malus domestica (related: apple),,,,fruit,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,reduced,,increased ; defective,reduced,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,36766008,PubMed,10.3390/foods12030479,Foods. 2023 Jan 19;12(3):479. doi: 10.3390/foods12030479,wangy1974@ujs.edu.cn,Pathogenicity assays revealed that the ΔPeclg mutant showed significant decrease in virulence and infectious growth on apple fruits.,J Zhou 2023,2023,1 gene,Zhou-2023-Transcriptome Analysis and Functiona,BACTH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22507,PHI:124448,UniProt,A0A9P7R4U7,GenBank,KAG7047851,,,Coll-153,ATG8,,,,,,,1209932,Colletotrichum scovillei,,KC05,anthracnose,eudicots,4072,Capsicum annuum (no common name found),,,,Fruits,autophagy protein,,,,reduced virulence,,,yes,,low disease severity,reduced,,wild type,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,36721786,PubMed,10.1080/12298093.2022.2148393,Mycobiology. 2022 Dec 12;50(6):467-474.,kims@kangwon.ac.kr,"ΔCsatg8 was greatly reduced in causing anthracnose disease, whereas both the wild-type and Csatg8c caused severe anthracnose disease after 10 days",K H Lee 2022,2022,1 gene,Lee-2022-The Autophagy Protein CsATG8 is Invol,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22508,PHI:124449,UniProt,G4N4K3,GenBank,EHA52018,,,70-15,PDX1 (MGG_05980),chromosome 3,,,MGG_11513; MGG_04719,UniProt: G4NAY4; GenBank: EHA48746; UniProt: G4MQX3; GenBank: EHA58204,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,pyridoxine biosynthesis protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full,,,NN,36824685,PubMed,10.3389/fcimb.2023.1099967,Front Cell Infect Microbiol. 2023 Feb 7;13:1099967,zhlji@yzu.edu.cn,The two MoPDX1 deletion mutants presented the most restricted lessons and bits of typical lesions of rice blast compared to that caused by Guy11 and complementary strains.,L Yang 2023,2023,1 gene,Yang-2023-Pyridoxine biosynthesis protein MoPd,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22509,PHI:124449,UniProt,G4N4K3,GenBank,EHA52018,,,70-15,PDX1 (MGG_05980),chromosome 3,,,MGG_11513; MGG_04719,UniProt: G4NAY4; GenBank: EHA48746; UniProt: G4MQX3; GenBank: EHA58204,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),,,,leaves,pyridoxine biosynthesis protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full,,,NN,36824685,PubMed,10.3389/fcimb.2023.1099967,Front Cell Infect Microbiol. 2023 Feb 7;13:1099967,zhlji@yzu.edu.cn,Exogenous addition of commercial VB6 could also rescue the pathogenicity defect of the two ΔMopdx1 mutants on barely leaves.,L Yang 2023,2023,1 gene,Yang-2023-Pyridoxine biosynthesis protein MoPd,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22510,PHI:124450,UniProt,A0A0J9UQH7,GenBank,KNB00426,,,4287,Asp (FOXG_03994),chromosome 4,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Alisa Craig,,,Seedlings,aspartic proteases,,,,reduced virulence,,,,,low disease severity,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36760509,PubMed,10.3389/fmicb.2023.1103418,Front Microbiol. 2023 Jan 25;14:1103418,wliang1@qau.edu.cn,Significantly reduced disease symptoms were detected in tomato seedlings inoculated with all the five knockout strains.,C Wang 2023,2023,1 gene,Wang-2023-The secreted FolAsp aspartic proteas,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22511,PHI:124450,UniProt,A0A0J9UQH7,GenBank,KNB00426,,,4287,Asp (FOXG_03994),chromosome 4,,,,,,5507,Fusarium oxysporum,426428,f. sp. lycopersici 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Alisa Craig,,,Seedlings,aspartic proteases,,,,increased virulence (hypervirulence),,,,,high disease severity,wild type,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,36760509,PubMed,10.3389/fmicb.2023.1103418,Front Microbiol. 2023 Jan 25;14:1103418,wliang1@qau.edu.cn,overexpression of FolAsp significantly caused more severe disease symptoms compared with the WT.,C Wang 2023,2023,1 gene,Wang-2023-The secreted FolAsp aspartic proteas,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22512,PHI:124451,UniProt,A0A2C5W8X0,GenBank,PHH50059,,,CBS 114723,swi6,,,,,,,5158,Ceratocystis fimbriata,,BMPZ13,,eudicots,4120,Ipomoea batatas (related: sweet potato),Shang 19,,,Roots,transcription factor,,,MAPK signaling pathway,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38004677,PubMed,10.3390/microorganisms11112666,Microorganisms. 2023 Oct 30;11(11):2666,lwli@jsnu.edu.cn,Pathogenicity assays on sweet potato storage roots revealed a significant decrease in virulence in the mutant.,H Cong 2023,2023,1 gene,Cong-2023-The Mechanism of Transcription Facto,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22513,PHI:124452,UniProt,I1RLA7,GenBank,CEF87207,,,PH-1,PKS2 (FGSG_04694),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1 (NRRL 31084),Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),USU-Apogee,,,Spikelets,polyketide synthase,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,hydrogen peroxide (H2O2);menadione,hydrogen peroxide (H2O2): CHEBI:16240; ;menadione: CHEBI:28869,,,,,gene deletion: full,,,NN,38025899,PubMed,10.3389/ffunb.2023.1264366,Front Fungal Biol. 2023 Nov 10;4:1264366,tes@bio.aau.dk,"Symptoms of FHB were observed on wheat ears infected with the WT and PKS2 mutants, no symptoms were observed for mock-inoculated wheat ears.",M M Severinsen 2023,2023,1 gene,Severinsen-2023-Filling out the gaps - identif,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22514,PHI:124452,UniProt,I1RLA7,GenBank,CEF87207,,,PH-1,PKS2 (FGSG_04694),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1 (NRRL 31084),Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),USU-Apogee,,,Spikelets,polyketide synthase,,,,reduced virulence,,,,,wild type,,,wild type,,no,hydrogen peroxide (H2O2);menadione,hydrogen peroxide (H2O2): CHEBI:16240; ;menadione: CHEBI:28869,,,,,altered gene expression / gene regulation: overexpression,,,NN,38025899,PubMed,10.3389/ffunb.2023.1264366,Front Fungal Biol. 2023 Nov 10;4:1264366,tes@bio.aau.dk,Symptoms of FHB were observed on wheat ears infected with the OE mutant was less than WT and deletion mutants.,M M Severinsen 2023,2023,1 gene,Severinsen-2023-Filling out the gaps - identif,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22515,PHI:124453,UniProt,W7LM77,GenBank,EWG40498,,,7600,Med1 (FVEG_02872),chromosome 5,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),,,,Seedlings,transcriptional coactivator,,,starch metabolism pathway,reduced virulence,,,,,less symptoms,reduced,,reduced,reduced,no,,,,,,,gene deletion: full,,,NN,37999515,PubMed,10.3390/toxins15110652,Toxins (Basel). 2023 Nov 13;15(11):652,yituyong@hunau.net,Med1 mutant exhibited less seedling rot symptoms compared with the WT.,Z Zhou 2023,2023,1 gene,Zhou-2023-Characterization of Fusarium vertici,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22516,PHI:124453,UniProt,W7LM77,GenBank,EWG40498,,,7600,Med1 (FVEG_02872),chromosome 5,Δ LxxLL,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),,,,Seedlings,transcriptional coactivator,,,starch metabolism pathway,increased virulence (hypervirulence),,,,,severe symptoms,increased,,reduced,reduced,no,,,,,,,gene deletion: full,,,NN,37999515,PubMed,10.3390/toxins15110652,Toxins (Basel). 2023 Nov 13;15(11):652,yituyong@hunau.net,FvMed1ΔLxxLL exhibited more severe seedling rot symptoms 7 days after inoculation when compared with the M3125 wild-type strain.,Z Zhou 2023,2023,1 gene,Zhou-2023-Characterization of Fusarium vertici,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22517,PHI:124453,UniProt,W7LM77,GenBank,EWG40498,,,7600,Med1 (FVEG_02872),chromosome 5,LxxLL motif was converted to the LxxAA motif through two amino acid substitutions.,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),,,,Seedlings,transcriptional coactivator,,,starch metabolism pathway,increased virulence (hypervirulence),,,,,severe symptoms,increased,,reduced,reduced,no,,,,,,,gene mutation ; gene deletion: full,,,NN,37999515,PubMed,10.3390/toxins15110652,Toxins (Basel). 2023 Nov 13;15(11):652,yituyong@hunau.net,FvMed1ΔLxxAA exhibited more severe seedling rot symptoms 7 days after inoculation when compared with the M3125 wild-type strain.,Z Zhou 2023,2023,1 gene,Zhou-2023-Characterization of Fusarium vertici,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22518,PHI:124454,UniProt,G4N0Z0,GenBank,EHA52368,,,70-15,Pmk1 (XP_003712175),chromosome 3,,,,,,2698418,Sclerotiophoma versabilis,,KC1,leaf spot disease,eudicots,418402,Pseudostellaria heterophylla (related: False Starwort),,,,Leaves,mitogen-activated protein kinase PMK11,,,mitogen-activated protein kinase (MAPK) signaling pathway,reduced virulence,,,yes,,smaller lesions,,,reduced ; defective,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,37108909,PubMed,10.3390/jof9040455,J Fungi (Basel). 2023 Apr 7;9(4):455,kuangyb@ndnu.edu.cn,ΔSvpmk1 failed to cause serious disease symptoms on the susceptible host leaves.,F Abah 2023,2023,2 genes,Abah-2023-Mitogen-Activated Protein Kinases Sv,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22519,PHI:124455,UniProt,G4N374,GenBank,EHA52630,,,70-15,Mps1 (XP_003712437),chromosome 3,,,,,,2698418,Sclerotiophoma versabilis,,KC1,leaf spot disease,eudicots,418402,Pseudostellaria heterophylla (related: False Starwort),,,,Leaves,mitogen-activated protein kinase MPS1,,,mitogen-activated protein kinase (MAPK) signaling pathway,reduced virulence,,,yes,,smaller lesions,,,reduced ; defective,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,37108909,PubMed,10.3390/jof9040455,J Fungi (Basel). 2023 Apr 7;9(4):455,kuangyb@ndnu.edu.cn,ΔSvmps1 failed to cause serious disease symptoms on the susceptible host leaves.,F Abah 2023,2023,2 genes,Abah-2023-Mitogen-Activated Protein Kinases Sv,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22520,PHI:124456,UniProt,P81702,GenBank,AGQ22233,,,CBS115175,Cp1,,,,,,,538528,Colletotrichum camelliae,,CCA,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),Hongyan 12; Longjing 43; Jinxuan; Guiding; Beishan,,,leaves,cerato-platanin protein,,,lipid metabolism pathway,reduced virulence,,,,,smaller necrotic area,reduced,,increased,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37090093,PubMed,10.1093/hr/uhad028,Hortic Res. 2023 Feb 21;10(4):uhad028,shouan@jlu.edu.cn,The lesion size caused by CcCp1 mutant was much smaller compared with the wild-type CCA.,S Liu 2023,2023,1 gene,Liu-2023-Tea plant (Camellia sinensis) lipid m,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22521,PHI:124457,UniProt,Q8XS97,GenBank,CAD17734,,,GMI1000,cbhA,,,,,,,1310165,Ralstonia pseudosolanacearum,,OE1-1,bacterial wilt disease,eudicots,4081,Solanum lycopersicum (related: tomato),Ohgata-Fukuju,,,Roots,"β-1,4-cellobiohydrolase",,,,loss of pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36912776,PubMed,10.1111/mpp.13322,Mol Plant Pathol. 2023 Jun;24(6):549-559,yhikichi@kochi-u.ac.jp,All tomato plants inoculated with strain OE1-1 exhibited wilt symptoms and were dead by 10 days after inoculation where ΔcbhA had lost its virulence.,W Senuma 2023,2023,1 gene,"Senuma-2023-?-1,4-Cellobiohydrolase is involve",BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22522,PHI:124458,UniProt,A0A384J5G5,GenBank,ATZ45798,,,B05.10,Msn2 (Bcin01p05160),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicot,3885,Phaseolus vulgaris (related: string bean),,,,Leaves,transcription factor,,,,reduced virulence,,,,,,increased,,reduced ; defective,increased,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37915851,PubMed,10.3389/fmicb.2023.1247072,Front Microbiol. 2023 Oct 17;14:1247072. doi: 10.3389/fmicb.2023.1247072. eCollection 2023,liangm2008@outlook.com,"Disruption of the BcMsn2 gene severely impaired vegetative growth, sclerotium formation, conidial yield, and fungal virulence.",P Lu 2023,2023,1 gene,Lu-2023-A novel zinc finger transcription fact,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22523,PHI:124458,UniProt,A0A384J5G5,GenBank,ATZ45798,,,B05.10,Msn2 (Bcin01p05160),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicot,4081,Solanum lycopersicum (related: tomato),,,,Fruits,transcription factor,,,,reduced virulence,,,,,,increased,,reduced ; defective,increased,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37915851,PubMed,10.3389/fmicb.2023.1247072,Front Microbiol. 2023 Oct 17;14:1247072. doi: 10.3389/fmicb.2023.1247072. eCollection 2023,liangm2008@outlook.com,"Disruption of the BcMsn2 gene severely impaired vegetative growth, sclerotium formation, conidial yield, and fungal virulence.",P Lu 2023,2023,1 gene,Lu-2023-A novel zinc finger transcription fact,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22524,PHI:124458,UniProt,A0A384J5G5,GenBank,ATZ45798,,,B05.10,Msn2 (Bcin01p05160),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicot,3750,Malus domestica (related: apple),,,,Fruits,transcription factor,,,,reduced virulence,,,,,,increased,,reduced ; defective,increased,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37915851,PubMed,10.3389/fmicb.2023.1247072,Front Microbiol. 2023 Oct 17;14:1247072. doi: 10.3389/fmicb.2023.1247072. eCollection 2023,liangm2008@outlook.com,"Disruption of the BcMsn2 gene severely impaired vegetative growth, sclerotium formation, conidial yield, and fungal virulence.",P Lu 2023,2023,1 gene,Lu-2023-A novel zinc finger transcription fact,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22525,PHI:124458,UniProt,A0A384J5G5,GenBank,ATZ45798,,,B05.10,Msn2 (Bcin01p05160),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicot,23211,Pyrus communis (related: pear),,,,Fruits,transcription factor,,,,reduced virulence,,,,,,increased,,reduced ; defective,increased,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37915851,PubMed,10.3389/fmicb.2023.1247072,Front Microbiol. 2023 Oct 17;14:1247072. doi: 10.3389/fmicb.2023.1247072. eCollection 2023,liangm2008@outlook.com,"Disruption of the BcMsn2 gene severely impaired vegetative growth, sclerotium formation, conidial yield, and fungal virulence.",P Lu 2023,2023,1 gene,Lu-2023-A novel zinc finger transcription fact,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22526,PHI:124459,UniProt,G2WX74,GenBank,EGY21329,,,VdLs.17,Tps1 (VDAG_02853),chromosome 3,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicot,4100,Nicotiana benthamiana (no common name found),,,,Seedlings,trehalose phosphate synthase/phosphatase (TPS/TPP),,,trehalose biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,Congo red;calcofluor white (CFW),Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36989041,PubMed,10.1094/MPMI-03-23-0024-R,Mol Plant Microbe Interact. 2023 Sep;36(9):572-583,ylwang@bjfu.edu.cn,Deletion of VdTps1 did not alter any phenotype compared with the wild-type strain.,L Xiao 2023,2023,3 genes,Xiao-2023-VdTps2 Modulates Plant Colonization,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22527,PHI:124460,UniProt,G2WVE0,GenBank,EGY20265,,,VdLs.17,Tps2 (VDAG_02281),chromosome 7,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicot,4100,Nicotiana benthamiana (no common name found),,,,Seedlings,trehalose phosphate synthase/phosphatase (TPS/TPP),,,trehalose biosynthesis pathway,reduced virulence,,,,,,reduced,,reduced,,no,Congo red;calcofluor white (CFW),Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36989041,PubMed,10.1094/MPMI-03-23-0024-R,Mol Plant Microbe Interact. 2023 Sep;36(9):572-583,ylwang@bjfu.edu.cn,Deletion of VdTps2 delayed disease symptom development as evident by the reduced virulence and decreased biomass.,L Xiao 2023,2023,3 genes,Xiao-2023-VdTps2 Modulates Plant Colonization,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22528,PHI:124460,UniProt,G2X160,GenBank,EGY22551,,,VdLs.17,Tps3 (VDAG_03989),chromosome 3,,,,,,27337,Verticillium dahliae,,XS11,vascular wilt,eudicot,4100,Nicotiana benthamiana (no common name found),,,,Seedlings,trehalose phosphate synthase/phosphatase (TPS/TPP),,,trehalose biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,,no,Congo red;calcofluor white (CFW),Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36989041,PubMed,10.1094/MPMI-03-23-0024-R,Mol Plant Microbe Interact. 2023 Sep;36(9):572-583,ylwang@bjfu.edu.cn,Deletion of VdTps3 did not alter any phenotype compared with the wild-type strain.,L Xiao 2023,2023,3 genes,Xiao-2023-VdTps2 Modulates Plant Colonization,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22529,PHI:124461,UniProt,A0A2C5X0C5,GenBank,PHH51727,,,CBS 114723,Erp3,,,,,,,5158,Ceratocystis fimbriata,,BMPZ13,canker stain disease,eudicots,4120,Ipomoea batatas (related: sweet potato),,,,Roots; Leaves; Seedlings,putative membrane protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;dithiothreitol (DTT);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;dithiothreitol (DTT): CHEBI:42170; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38048937,PubMed,10.1016/j.fgb.2023.103846,Fungal Genet Biol. 2023 Dec 2;170:103846,lilianwei77@126.com,"The wild-type BMPZ13 and the complemented strain caused typical lesions, which were larger than the very small lesions caused by the ΔCferp3 mutants.",C Li 2023,2023,1 gene,Li et al 2023 1-s2.0-S1087184523000774-main,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22530,PHI:124462,UniProt,G4MT55,GenBank,EHA55520,,,70-15,RRP8 (MGG_07132),chromosome 2,,,,,,318829,Magnaporthe oryzae,1271791,KJ201,rice blast,monocots,4530,Oryza sativa (related: rice),Nakdong,,,Leaves,nucleolar protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37929010,PubMed,10.1080/12298093.2023.2257996,Mycobiology. 2023 Sep 25;51(5):273-280,jjeon@yu.ac.kr,"The wild-type and complementation strains showed numerous lesions at five days post inoculation (dpi), whereas in the mutant, only a few lesions were observed.",M Kim 2023,2023,1 gene,"Kim-2023-A Nucleolar Protein, MoRRP8 Is Requir",BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22531,PHI:124463,UniProt,A7EZ51,GenBank,EDN94743,,,1980,SS1G_10617,,,,,,,5180,Sclerotinia sclerotiorum,,Ep-1PNA367,white mould,monocots,3708,Brassica napus (related: rape),QingYou 1,,,Leaves,glucoamylase,,,starch degradation pathway,reduced virulence,,,,,smaller lesions,,,reduced,,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full ; gene complementation,,,NN,37905914,PubMed,10.1128/spectrum.02612-23,Microbiol Spectr. 2023 Dec 12;11(6):e0261223. doi: 10.1128/spectrum.02612-23. Epub 2023 Oct 31,daohongjiang@mail.hzau.edu.cn,KO-10617 mutant had dramatically reduced pathogenicity compared to that of the wildtype.,B Tian 2023,2023,2 genes,Tian-2023-Transcriptional plasticity of schizo,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22532,PHI:124463,UniProt,A7EZ51,GenBank,EDN94743,,,1980,SS1G_10617,,,,,,,5180,Sclerotinia sclerotiorum,,Ep-1PNA367,white mould,monocots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,glucoamylase,,,starch degradation pathway,reduced virulence,,,,,smaller lesions,,,reduced,,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full ; gene complementation,,,NN,37905914,PubMed,10.1128/spectrum.02612-23,Microbiol Spectr. 2023 Dec 12;11(6):e0261223. doi: 10.1128/spectrum.02612-23. Epub 2023 Oct 31,daohongjiang@mail.hzau.edu.cn,KO-10617 mutant had dramatically reduced pathogenicity compared to that of the wildtype.,B Tian 2023,2023,2 genes,Tian-2023-Transcriptional plasticity of schizo,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22533,PHI:124464,UniProt,A7F878,GenBank,EDN98949,,,1980,SS1G_13809,,,,,,,5180,Sclerotinia sclerotiorum,,Ep-1PNA367,white mould,monocots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,glucoamylase,,,starch degradation pathway,unaffected pathogenicity,,,,,wild type,,,reduced,,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full ; gene complementation,,,NN,37905914,PubMed,10.1128/spectrum.02612-23,Microbiol Spectr. 2023 Dec 12;11(6):e0261223. doi: 10.1128/spectrum.02612-23. Epub 2023 Oct 31,daohongjiang@mail.hzau.edu.cn,The lesion caused by the KO-13809 showed no significant difference compared to wild type.,B Tian 2023,2023,2 genes,Tian-2023-Transcriptional plasticity of schizo,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22534,PHI:124464,UniProt,A7F878,GenBank,EDN98949,,,1980,SS1G_13809,,,,,,,5180,Sclerotinia sclerotiorum,,Ep-1PNA367,white mould,monocots,3708,Brassica napus (related: rape),QingYou 1,,,Leaves,glucoamylase,,,starch degradation pathway,unaffected pathogenicity,,,,,wild type,,,reduced,,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full ; gene complementation,,,NN,37905914,PubMed,10.1128/spectrum.02612-23,Microbiol Spectr. 2023 Dec 12;11(6):e0261223. doi: 10.1128/spectrum.02612-23. Epub 2023 Oct 31,daohongjiang@mail.hzau.edu.cn,The lesion caused by the KO-13809 showed no significant difference compared to wild type.,B Tian 2023,2023,2 genes,Tian-2023-Transcriptional plasticity of schizo,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22535,PHI:124465,UniProt,A0A7Z6XRX8,GenBank,RMN80487,,,ICMP 15205,HexR,,,,,,,757414,Pseudomonas cannabina,,"pv. Alisalensis, strain KB211",blight disease,eudicots,3712,Brassica oleracea (no common name found),"var. capitata, Kinkei 201",,,leaves,transcription factor,,,,loss of pathogenicity,,,,,no symptoms,,,defective,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37110448,PubMed,10.3390/microorganisms11041025,Microorganisms. 2023 Apr 14;11(4):1025,sakata.nanami.td@alumni.tsukuba.ac.jp,"Cabbage leaves inoculated with Pcal WT showed severe chlorosis, but the Pcal hexR mutant showed no symptoms.",N Sakata 2023,2023,2 genes,Sakata-2023-HexR Transcription Factor Contribu,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22536,PHI:124466,UniProt,A0A4V0ZKN3,GenBank,QBI60714,,,Ps25,HexR,,,,,,,317,Pseudomonas syringae,223283,pv. Tomato DC3000,,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,seedlings,transcription factor,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37110448,PubMed,10.3390/microorganisms11041025,Microorganisms. 2023 Apr 14;11(4):1025,sakata.nanami.td@alumni.tsukuba.ac.jp,"Disease symptoms caused by Pst WT showed severe chlorosis, although disease symptoms byPst ΔhexR showed less chlorosis compared to Pst WT.",N Sakata 2023,2023,2 genes,Sakata-2023-HexR Transcription Factor Contribu,BATCH_128A,2023-12-01,MC,,,,,,,,,,,,,
,,Record 22537,PHI:124467,UniProt,E3Q704,GenBank,EFQ26642,,,M1.001,Fs06761 (GLRG02462),,,,,,,42676,Fusarium sacchari,,SRR18652388,pokkah boeng disease,monocots,4547,Saccharum officinarum (related: sugarcane),Zhongzhe 1,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller necrotic area,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37962343,PubMed,10.1128/spectrum.01452-23,Microbiol Spectr. 2023 Dec 12;11(6):e0145223.,mqzhang@ufl.edu,"The pathogenicity test showed that virulence to pokkah boeng disease of ΔFsCFEMs was significantly weakened, and the necrotic area of the wild type was larger than that of the mutant.",Z Huang 2023,2023,3 genes,Huang-2023-Identification of common fungal ext,BATCH_128B,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22538,PHI:124468,UniProt,E3QD10,GenBank,EFQ28782,,,M1.001,Fs08184 (GLRG03926),,,,,,,42676,Fusarium sacchari,,SRR18652388,pokkah boeng disease,monocots,4547,Saccharum officinarum (related: sugarcane),Zhongzhe 1,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller necrotic area,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37962343,PubMed,10.1128/spectrum.01452-23,Microbiol Spectr. 2023 Dec 12;11(6):e0145223.,mqzhang@ufl.edu,"The pathogenicity test showed that virulence to pokkah boeng disease of ΔFsCFEMs was significantly weakened, and the necrotic area of the wild type was larger than that of the mutant.",Z Huang 2023,2023,3 genes,Huang-2023-Identification of common fungal ext,BATCH_128B,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22539,PHI:124469,UniProt,E3QRC0,GenBank,EFQ33408,,,M1.001,Fs13617 (GLRG08687),,,,,,,42676,Fusarium sacchari,,SRR18652388,pokkah boeng disease,monocots,4547,Saccharum officinarum (related: sugarcane),Zhongzhe 1,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller necrotic area,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37962343,PubMed,10.1128/spectrum.01452-23,Microbiol Spectr. 2023 Dec 12;11(6):e0145223.,mqzhang@ufl.edu,"The pathogenicity test showed that virulence to pokkah boeng disease of ΔFsCFEMs was significantly weakened, and the necrotic area of the wild type was larger than that of the mutant.",Z Huang 2023,2023,3 genes,Huang-2023-Identification of common fungal ext,BATCH_128B,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22540,PHI:124470,UniProt,A0A194WDN5,GenBank,KUI74504,,,03-8,SP1 (VM1G_10102),chromosome 13,,,,,,105487,Valsa mali,,,apple Valsa canker,eudicots,3750,Malus domestica (related: apple),Fuji,,,Twigs,effector gene,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,37118888,PubMed,10.1111/tpj.16262,Plant J. 2023 Aug;115(3):803-819,xiaosong04005@163.com,Deletion of VmSP1 did not affect the vegetative growth but significantly reduced the virulence of V. mali.,M Xu 2023,2023,1 gene,Xu-2023-A fungal microRNA-like,BATCH_128B,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22541,PHI:124471,UniProt,A0A0H3L3K7,GenBank,BAK12452,,,AJ13355,hvrB,,,,,,,553,Pantoea ananatis,,PNA 97-1R,necrosis in onion foliage and bulb tissues,monocot,4679,Allium cepa (related: onion),Century,,,Leaves; Bulb,hiVir gene,,,biosynthetic pathway,loss of pathogenicity,,,,,no necrotic lesions,,,,,no,,,,,,,gene deletion: full,,,NN,36797073,PubMed,10.1094/MPMI-11-22-0246-R,Mol Plant Microbe Interact. 2023 Jun;36(6):381-391,bkvitko@uga.edu,hvrB mutant was unable to cause necrotic foliar lesions.,G Y Shin 2023,2023,1 gene,Shin et al 2023 mpmi-11-22-0246-r,BATCH_128B,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22542,PHI:124472,UniProt,V6RAM6,GenBank,CEF79156,,,PH-1,FGSG_04194,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Zhengmai 366,,,spikelet,aldehyde dehydrogenase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38138019,PubMed,10.3390/microorganisms11122875,Microorganisms. 2023 Nov 28;11(12):2875,huanchenzhai@126.com,All the ALDH-deletion mutants had a substantially lower pathogenicity in the wheat heads compared to the control and wild type.,L Tang 2023,2023,6 genes,Tang-2023-Functional Characterization of Aldeh,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22543,PHI:124473,UniProt,V6QU99,GenBank,CEF71989,,,PH-1,FGSG_00139,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Zhengmai 366,,,spikelet,aldehyde dehydrogenase,,,,reduced virulence,,,,,,reduced,,wild type,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,38138019,PubMed,10.3390/microorganisms11122875,Microorganisms. 2023 Nov 28;11(12):2875,huanchenzhai@126.com,All the ALDH-deletion mutants had a substantially lower pathogenicity in the wheat heads compared to the control and wild type.,L Tang 2023,2023,6 genes,Tang-2023-Functional Characterization of Aldeh,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22544,PHI:124474,UniProt,V6R9L8,GenBank,CEF88544,,,PH-1,FGSG_05375,chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Zhengmai 366,,,spikelet,aldehyde dehydrogenase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,38138019,PubMed,10.3390/microorganisms11122875,Microorganisms. 2023 Nov 28;11(12):2875,huanchenzhai@126.com,All the ALDH-deletion mutants had a substantially lower pathogenicity in the wheat heads compared to the control and wild type.,L Tang 2023,2023,6 genes,Tang-2023-Functional Characterization of Aldeh,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22545,PHI:124475,UniProt,V6R2Z2,GenBank,CEF73032,,,PH-1,FGSG_00979,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Zhengmai 366,,,spikelet,aldehyde dehydrogenase,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,38138019,PubMed,10.3390/microorganisms11122875,Microorganisms. 2023 Nov 28;11(12):2875,huanchenzhai@126.com,All the ALDH-deletion mutants had a substantially lower pathogenicity in the wheat heads compared to the control and wild type.,L Tang 2023,2023,6 genes,Tang-2023-Functional Characterization of Aldeh,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22546,PHI:124476,UniProt,V6R0W1,GenBank,CEF74407,,,PH-1,FGSG_02160,chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Zhengmai 366,,,spikelet,aldehyde dehydrogenase,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,38138019,PubMed,10.3390/microorganisms11122875,Microorganisms. 2023 Nov 28;11(12):2875,huanchenzhai@126.com,All the ALDH-deletion mutants had a substantially lower pathogenicity in the wheat heads compared to the control and wild type.,L Tang 2023,2023,6 genes,Tang-2023-Functional Characterization of Aldeh,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22547,PHI:124477,UniProt,A0A1C3YKB7,GenBank,SCB64826,,,PH-1,FGSG_05831,chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Zhengmai 366,,,spikelet,aldehyde dehydrogenase,,,,reduced virulence,,,,,,reduced,,reduced,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,38138019,PubMed,10.3390/microorganisms11122875,Microorganisms. 2023 Nov 28;11(12):2875,huanchenzhai@126.com,All the ALDH-deletion mutants had a substantially lower pathogenicity in the wheat heads compared to the control and wild type.,L Tang 2023,2023,6 genes,Tang-2023-Functional Characterization of Aldeh,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22548,PHI:124478,UniProt,G4N6C7,GenBank,EHA50649,,,70-15,Sec24B (MGG_06569),chromosome 4,,,MoRas1; MoSep4; MoMst5; MoSec24A (MGG_09564); MoSec23 (MGG_06910),UniProt: G4N1S3; GenBank: EHA52438; UniProt: A4QUL1; GenBank: EHA52370; UniProt: A4R1J7; Gen,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),Guy11,,,Leaves,,,,mitogen-activated protein kinase (MAPK) signaling pathway,reduced virulence,,,,,smaller necrotic area,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36699840,PubMed,10.3389/fpls.2022.1074107,Front Plant Sci. 2023 Jan 9;13:1074107.,xhliu@zju.edu.cn,"The targeted disruption of MoSec24B led to decreased growth, reduced conidiation, decreased ability to infect, which resulted in reduced pathogenicity to the host plant.",H Qian 2023,2023,1 gene,Qian-2022-The COPII subunit MoSec24B is involv,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22549,PHI:124478,UniProt,G4N6C7,GenBank,EHA50649,,,70-15,Sec24B (MGG_06569),chromosome 4,,,MoRas1; MoSep4; MoMst5; MoSec24A (MGG_09564); MoSec23 (MGG_06910),UniProt: G4N1S3; GenBank: EHA52438; UniProt: A4QUL1; GenBank: EHA52370; UniProt: A4R1J7; Gen,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO39,,,Leaves,,,,mitogen-activated protein kinase (MAPK) signaling pathway,reduced virulence,,,,,smaller necrotic area,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36699840,PubMed,10.3389/fpls.2022.1074107,Front Plant Sci. 2023 Jan 9;13:1074107.,xhliu@zju.edu.cn,"The targeted disruption of MoSec24B led to decreased growth, reduced conidiation, decreased ability to infect, which resulted in reduced pathogenicity to the host plant.",H Qian 2023,2023,1 gene,Qian-2022-The COPII subunit MoSec24B is involv,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22550,PHI:124479,UniProt,P38182,GenBank,CAA56032,,,S 288c,Atg8,chromosome 2,,,,,,100870,Peronophythora litchii,,SHS3,litchi downy blight,eudicots,151069,Litchi chinensis (related: Tender litchi),,,,Leaves; fruit,autophagy-related gene,,,autophagy pathway,reduced virulence,,,,,smaller lesions,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);glycerol;Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;glycerol: CHEBI:17754; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38084976,PubMed,10.1128/spectrum.03531-23,Microbiol Spectr. 2024 Jan 11;12(1):e0353123.,qhchen@hainanu.edu.cn,"The pathogenicity test shows that the lesion areas on litchi leaves and fruits caused by ΔPlatg8 are significantly attenuated compared with the wild type,",G Yu 2024,2024,1 gene,Yu-2024-PlAtg8-mediated autophagy regulates ve,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22551,PHI:124480,UniProt,A0A0J9UVX2,GenBank,KNB02650,,,4287,ck1 (FOXG_05428),chromosome 7,,,,,,5507,Fusarium oxysporum,426428,f. sp. Lycopersici 4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Moneymaker,,,Roots,regulator,,,,loss of pathogenicity,,,,,,reduced,,reduced,wild type,no,NaCl;KCl;sodium dodecyl sulphate (SDS),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full ; gene complementation,,,NN,36547634,PubMed,10.3390/jof8121300,J Fungi (Basel). 2022 Dec 15;8(12):1300,ge2dipia@uco.es,Ck1 is a key regulator of the development and virulence of F. oxysporum.,M Mariscal 2022,2022,1 gene,Mariscal-2022-Fusarium oxysporum Casein Kinase,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22552,PHI:124481,UniProt,A0A384JL35,GenBank,ATZ51084,,,B05.10,Spd1,chromosome BCIN06,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,4054,Panax ginseng,,,,Leaves,Zn(II)2Cys6 transcription factor,,,,reduced virulence,,,,,tiny necrosis,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38107400,PubMed,10.1016/j.jgr.2023.08.005,J Ginseng Res. 2023 Nov;47(6):773-783,shouan.camellia@outlook.com,The typical necrosis appeared in both B05.10 and the complement line incubated ginseng leaves while the lesions were tiny in ΔBcSpd1 mutants treated plants.,S Zhang 2023,2023,1 gene,Zhang-2023-Botrytis cinerea hypovirulent strai,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22553,PHI:124482,UniProt,A0A7U4NBB4,GenBank,AKO09093,,,CFBP7341,NIT24 (AKO15524.1),,,,,,,347,Xanthomonas oryzae,,pvs. Oryzicola RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),ZH11,,,Leaves,nitrilase enzyme family (NIT) gene,,,IAA synthesis pathway,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38069667,PubMed,10.1111/mpp.13409,Mol Plant Pathol. 2023 Dec 9;25(1):e13409.,xhding@sdau.edu.cn,"RS105_ΔNIT24 showed lesion lengths at 10 days post-inoculation which was markedly reduced lesion lengths upon rice, causing reductions of 32.4% in comparison to the WT and complemtation strain.",H Zhang 2023,2023,2 genes,Zhang-2023-NIT24 and NIT29-mediated IAA synthe,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22554,PHI:124483,UniProt,A0A5C2ERW5,GenBank,QEO97132,,,GX01,NIT29 (AKO15829.1),,,,,,,347,Xanthomonas oryzae,,pvs. Oryzicola RS105,leaf blight,monocots,4530,Oryza sativa (related: rice),ZH11,,,Leaves,nitrilase enzyme family (NIT) gene,,,IAA synthesis pathway,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38069667,PubMed,10.1111/mpp.13409,Mol Plant Pathol. 2023 Dec 9;25(1):e13409.,xhding@sdau.edu.cn,"RS105_ΔNIT29 showed lesion lengths at 10 days post-inoculation which was markedly reduced lesion lengths upon rice, causing reductions of 72.7% in comparison to the WT and complemtation strain.",H Zhang 2023,2023,2 genes,Zhang-2023-NIT24 and NIT29-mediated IAA synthe,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22555,PHI:124484,UniProt,A0A098DTB5,GenBank,CEF85111,,,PH-1,Ste3 (FGSG_07270),,chromosome 4,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Roblin,,,coleoptile,G-protein,,,CWI-MAPK pathway,reduced virulence,,,,,smaller lesions,increased,,wild type,,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,36377914,PubMed,10.1128/msphere.00456-22,mSphere. 2022 Dec 21;7(6):e0045622.,Michele.Loewen@nrc-cnrc.gc.ca,The Fgste3 strain showed an average 50% decrease in lesion length compared to the wild-type strain.,T Sharma 2022,2022,2 genes,Sharma-2022-Fusarium graminearum Ste3 G-Protei,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22556,PHI:124484,UniProt,A0A098DTB5,GenBank,CEF85111,,,PH-1,Ste3 (FGSG_07270),,chromosome 4,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),Roblin,,,coleoptile,G-protein,,,CWI-MAPK pathway,reduced virulence,,,,,smaller lesions,increased,,wild type,,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,36377914,PubMed,10.1128/msphere.00456-22,mSphere. 2022 Dec 21;7(6):e0045622.,Michele.Loewen@nrc-cnrc.gc.ca,The Fgste3 strain showed an average of 99% decrease in lesion length compared to the wild-type strain.,T Sharma 2022,2022,2 genes,Sharma-2022-Fusarium graminearum Ste3 G-Protei,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22557,PHI:124485,UniProt,A0A2H3H130,GenBank,CAG1972721,,,MDC_Fg202,Ste2,,,,,,,5518,Fusarium graminearum,,DAOM 233423,Fusarium head blight,eudicots,3702,Arabidopsis thaliana (related: thale cress),Roblin,,,coleoptile,G-protein,,,CWI-MAPK pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,36377914,PubMed,10.1128/msphere.00456-22,mSphere. 2022 Dec 21;7(6):e0045622.,Michele.Loewen@nrc-cnrc.gc.ca,The Fgste2 strain showed an average of 50% decrease in lesion length compared to the wild-type strain.,T Sharma 2022,2022,2 genes,Sharma-2022-Fusarium graminearum Ste3 G-Protei,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22558,PHI:124486,UniProt,G4N525,GenBank,EHA52936,,,70-15,Ste50,chromosome 3,,,,,,1209932,Colletotrichum scovillei,,KC05,anthracnose,monocots,4072,Capsicum annuum (no common name found),,,,fruit,adaptor protein,,,cAMP-mediated signaling and MAPK pathway,,,,yes,,,increased,,increased,reduced,no,NaCl;KCl,NaCl: CHEBI:26710; ;KCl: CHEBI:32588,,,,,gene deletion: full ; gene complementation,,,NN,36503188,PubMed,10.5423/PPJ.OA.06.2022.0074,Plant Pathol J. 2022 Dec;38(6):593-602,kims@kangwon.ac.kr,The mutant was completely non-pathogenic on pepper fruits with or without wounds.,J H Shin 2022,2022,1 gene,Shin-2022-The CsSTE50 Adaptor Protein in Mitog,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22559,PHI:124487,UniProt,A0A1D9QGE1,GenBank,APA13968,,,1980,Atg1 (Sscle_12g087380),chromosome 12,,,,,,5180,Sclerotinia sclerotiorum,,UF-1,white mould,eudicot,3847,Glycine max (related: soybean),,,,Leaves,autophagy-related gene,,,autophagy pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);mannitol;Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;mannitol: CHEBI:29864; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36547647,PubMed,10.3390/jof8121314,J Fungi (Basel). 2022 Dec 17;8(12):1314,yh_zhang@jlu.edu.cn,Virulence of ΔSsAtg1 was significantly decreased both on wounded and unwounded soybean leaves.,W Jiao 2022,2022,1 gene,Jiao-2022-The SsAtg1 Activating Autophagy Is R,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22560,PHI:124487,UniProt,A0A1D9QGE1,GenBank,APA13968,,,1980,Atg1 (Sscle_12g087380),chromosome 12,,,,,,5180,Sclerotinia sclerotiorum,,UF-1,white mould,eudicot,4100,Nicotiana benthamiana (no common name found),,,,Leaves,autophagy-related gene,,,autophagy pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);mannitol;Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;mannitol: CHEBI:29864; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36547647,PubMed,10.3390/jof8121314,J Fungi (Basel). 2022 Dec 17;8(12):1314,yh_zhang@jlu.edu.cn,Lesion area of the leaf inoculated with ΔSsAtg1 was significantly reduced in the tobacco plant.,W Jiao 2022,2022,1 gene,Jiao-2022-The SsAtg1 Activating Autophagy Is R,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22561,PHI:124488,UniProt,H1VCA4,GenBank,CCF37857,,,IMI 349063,Htf2,,,,,,,690256,Colletotrichum fructicola,,N425,anthracnose,eudicots,4442,Camellia sinensis (related: tea),Fuyun No. 6,,,Leaves,transcriptional regulator,,,,reduced virulence,,,,,,reduced,,reduced ; defective,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38137057,PubMed,10.3390/genes14122235,Genes (Basel). 2023 Dec 18;14(12):2235.,t9703@ndnu.edu.cn,"The results showed that the pathogenicity of CfHTF2 was weakened due to the loss of CfHTF2, which was presumably caused by the slowdown of vegetative growth in the colonies.",C Zhang 2023,2023,1 gene,Zhang-2023-CFHTF2 Is Needed for Vegetative Gro,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22562,PHI:124489,UniProt,A0A7I8H5V6,GenBank,BCM10226,,,MAFF 241647,radA,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Bonny Best,,,Seedlings,adhesin A,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full,,,NN,36688670,PubMed,10.1128/aem.01565-22,Appl Environ Microbiol. 2023 Feb 28;89(2):e0156522.,callen@wisc.edu,ΔradA had a minor but significant virulence defect early in disease compared to wild type.,M D Carter 2023,2023,1 gene,Carter-2023-Cell Density-Regulated Adhesins Co,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22563,PHI:124490,UniProt,A0A384J4E7,GenBank,ATZ45388,,,B05.10,rdr1 ((Bcin01g01810)),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,4081,Solanum lycopersicum (related: tomato),Heinz,,,Leaves,RNA-dependent RNA polymerase,,,,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38117848,PubMed,10.1371/journal.ppat.1011885,PLoS Pathog. 2023 Dec 20;19(12):e1011885.,a.weiberg@lmu.de,B.cinerea bcrdr1 knockout (ko) mutants exhibited reduced pathogenicity.,A P Cheng 2023,2023,2 genes,Cheng-2023-A fungal RNA-dependent RNA polymera,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22564,PHI:124490,UniProt,A0A384J4E7,GenBank,ATZ45388,,,B05.10,rdr1 ((Bcin01g01810)),chromosome BCIN01,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,RNA-dependent RNA polymerase,,,,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38117848,PubMed,10.1371/journal.ppat.1011885,PLoS Pathog. 2023 Dec 20;19(12):e1011885.,a.weiberg@lmu.de,B.cinerea bcrdr1 knockout (ko) mutants exhibited reduced pathogenicity.,A P Cheng 2023,2023,2 genes,Cheng-2023-A fungal RNA-dependent RNA polymera,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22565,PHI:124491,UniProt,A0A384JPM0,GenBank,ATZ52529,,,B05.10,rdr2 (Bcin08g02220),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,4081,Solanum lycopersicum (related: tomato),Heinz,,,Leaves,RNA-dependent RNA polymerase,,,,unaffected pathogenicity,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38117848,PubMed,10.1371/journal.ppat.1011885,PLoS Pathog. 2023 Dec 20;19(12):e1011885.,a.weiberg@lmu.de,B.cinerea bcrdr2 knockout (ko) mutants exhibited same pathogenicity as wild type.,A P Cheng 2023,2023,2 genes,Cheng-2023-A fungal RNA-dependent RNA polymera,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22566,PHI:124491,UniProt,A0A384JPM0,GenBank,ATZ52529,,,B05.10,rdr2 (Bcin08g02220),chromosome BCIN08,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,RNA-dependent RNA polymerase,,,,unaffected pathogenicity,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38117848,PubMed,10.1371/journal.ppat.1011885,PLoS Pathog. 2023 Dec 20;19(12):e1011885.,a.weiberg@lmu.de,B.cinerea bcrdr2 knockout (ko) mutants exhibited same pathogenicity as wild type.,A P Cheng 2023,2023,2 genes,Cheng-2023-A fungal RNA-dependent RNA polymera,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22567,PHI:124492,UniProt,I1RPM2,GenBank,SCB64846,,,PH-1,ugmA (FGSG_05997),chromosome 3,,,CHY1 (FGSG_07281),UniProt: A0A2H3HRX3; GenBank: CAG1963600,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Annong 8455,,,spikelet; Corn silk,UDP-galactopyranose mutase (UGMA),,,,reduced virulence,,,,,limited scab symptoms,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36656025,PubMed,10.1128/aem.01235-22,Appl Environ Microbiol. 2023 Feb 28;89(2):e0123522.,huaigu@jaas.ac.cn,"no data foundAfter 2 weeks of inoculation, PH-1 (disease index, 16.0) and the complemented strain (disease index, 12.5) caused typical blight symptoms and spread to the other spikelets where only 25% of ΔugmA mutant inoculated kernels (disease index, 0.2) showed limited scab symptoms.",S Cao 2023,2023,1 gene,Cao-2023-UDP-Galactopyranose Mutase Mediates C,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22568,PHI:124493,UniProt,G2WU90,GenBank,EGY17681,,,VdLs.17,VdERG2 (VDAG_01363),chromosome 1,,,,,,27337,Verticillium dahliae,,Vd080,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),,,,leaves; stem,C-8 sterol isomerase,,,ergosterol biosynthesis,reduced virulence,,,yes,,,reduced,,reduced,,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,36416932,PubMed,10.1007/s00294-022-01257-9,Curr Genet. 2023 Feb;69(1):25-40.,mkslch2013@163.com,"The conidial germination rate and conidial yield of ΔVdERG2 signifcantly decreased and abnormal conidia were produced; ΔVdERG2 could infect cotton, its pathogenicity was signifcantly impaired.",J Lv 2023,2023,1 gene,Lv-2023-VdERG2 was involved in ergosterol bios,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22569,PHI:124494,UniProt,Q6D6J5,GenBank,CAG74591,,,SCRI1043,FlhD,,,,,,PHI:124495,29471,Pectobacterium atrosepticum,218491,SCRI1043,soft rot of potato tubers and blackleg disease in potato stems,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,regulator,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36386642,PubMed,10.3389/fmicb.2022.999522,Front Microbiol. 2022 Oct 28:13:999522,ewanchung@korea.ac.kr,"With or without hopeaphenol treatment blackleg symptom was clearly reduced in mutant Pba strain (ΔflhDC), whereas the complemented stain (ΔflhDC(pflhDC) caused similar disease symptom as in wild-type strain.",J E Kang 2022,2022,2 genes,Kang et al 2022 fmicb-13-999522,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22570,PHI:124495,UniProt,Q6D6J4,GenBank,CAG74592,,,SCRI1043,FlhC,,,,,,PHI:124494,29471,Pectobacterium atrosepticum,218491,SCRI1043,soft rot of potato tubers and blackleg disease in potato stems,eudicots,4113,Solanum tuberosum (related: potato),,,,Tubers,regulator,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36386642,PubMed,10.3389/fmicb.2022.999522,Front Microbiol. 2022 Oct 28;13:999522.,ewanchung@korea.ac.kr,"With or without hopeaphenol treatment blackleg symptom was clearly reduced in mutant Pba strain (ΔflhDC), whereas the complemented stain (ΔflhDC(pflhDC) caused similar disease symptom as in wild-type strain.",J E Kang 2022,2022,2 genes,Kang et al 2022 fmicb-13-999522,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22571,PHI:124496,UniProt,Q87Z81,GenBank,AAO57024,,,DC3000,AefR (PSPTO_3549),,aefR::Tn5m34,,,,,317,Pseudomonas syringae,223283,DC3000,bacterial speck of tomato,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,Leaves,TetR family transcriptional regulator,,,,reduced virulence,,,,,,,,increased,,no,,,,,,,gene mutation,,,NN,38079389,PubMed,10.1094/MPMI-10-23-0170-R,Mol Plant Microbe Interact. 2023 Dec 11. doi: 10.1094/MPMI-10-23-0170-R. Online ahead of print,kunkel@wustl.edu,aefR mutant has altered virulence on Arabidopsis.,J M Johnson 2023,2023,1 gene,Johnson & Kunkle 2023 mpmi-10-23-0170-r,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22572,PHI:124497,UniProt,D4HWX8,GenBank,CBA21540,,,CFPB1430,rcsC,,,,,,,552,Erwinia amylovora,,Ea17-2187,fire blight,eudicots,3767,Pyrus pyrifolia (related: sha li),Shingo,,,fruit,sensor histidine kinase,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene mutation ; gene complementation,,,NN,38079389,PubMed,10.1094/MPMI-10-23-0170-R,Mol Plant Microbe Interact. 2023 Dec 11,jaehoon@snu.ac.kr,Mutation in the rcsC gene was responsible for the reduced virulence of Ea17-2187 in pear fruit.,J M Johnson 2023,2023,2 genes,Kang et al 2023 pdis-09-23-1836-sc,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22573,PHI:124497,UniProt,D4HWX8,GenBank,CBA21540,,,CFPB1430,rcsC,,,,,,,552,Erwinia amylovora,,Ea17-2187,fire blight,eudicots,3750,Malus domestica (related: apple),Fuji,,,fruit,sensor histidine kinase,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene mutation ; gene complementation,,,NN,38079389,PubMed,10.1094/MPMI-10-23-0170-R,Mol Plant Microbe Interact. 2023 Dec 11,jaehoon@snu.ac.kr,Mutation in the rcsC gene was was not pathogenic to apple fruit.,J M Johnson 2023,2023,2 genes,Kang et al 2023 pdis-09-23-1836-sc,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22574,PHI:124498,UniProt,D4HVM9,GenBank,CBA19486,,,CFPB1430,hrpL,,,,,,,552,Erwinia amylovora,,Ea19-7,fire blight,eudicots,3767,Pyrus pyrifolia (related: sha li),Shingo,,,fruit,RNA polymerase sigma factor,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene mutation ; gene complementation,,,NN,38079389,PubMed,10.1094/MPMI-10-23-0170-R,Mol Plant Microbe Interact. 2023 Dec 11,jaehoon@snu.ac.kr,Mutation in the hrpL gene was responsible for the reduced virulence of Ea19-7 in pear fruit.,J M Johnson 2023,2023,2 genes,Kang et al 2023 pdis-09-23-1836-sc,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22575,PHI:124498,UniProt,D4HVM9,GenBank,CBA19486,,,CFPB1430,hrpL,,,,,,,552,Erwinia amylovora,,Ea19-7,fire blight,eudicots,3750,Malus domestica (related: apple),Fuji,,,fruit,RNA polymerase sigma factor,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene mutation ; gene complementation,,,NN,38079389,PubMed,10.1094/MPMI-10-23-0170-R,Mol Plant Microbe Interact. 2023 Dec 11,jaehoon@snu.ac.kr,Mutation in the hrpL gene was was not pathogenic to apple fruit.,J M Johnson 2023,2023,2 genes,Kang et al 2023 pdis-09-23-1836-sc,BATCH_129A,2024-01-01,MC,,,,,,,,,,,,,
,,Record 22576,PHI:124499,UniProt,X0JUF1,GenBank,EXM00107,,,54006,Sec4 (FOIG_08151),chromosome unknown,FoSec2 interact with dominant-negative FoSec4; FoGyp5 interact with dominant active FoSec4.,,,,,2502994,Fusarium odoratissimum,,58,banana Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),AAA,,,Corms; Leaves,small GTPase,,,,loss of pathogenicity,,,,,,reduced,,reduced,reduced,no,NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36012867,PubMed,10.3390/jof8080880,J Fungi (Basel). 2022 Aug 20;8(8):880.,wangzh@fafu.edu.cn,"The banana plantlets inoculated with ΔFoSEC4 showed same chlamydospores as wild type and reduced microconidia, macroconidia, vegetative growth and only slightly reduced necrosis symptoms compared to complementary and wild type.",Y Zheng 2022,2022,3 genes,Zheng-2022-Small GTPase FoSec4-Mediated Protei,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22577,PHI:124500,UniProt,X0J2K1,GenBank,EXL95413,,,54006,Sec2 (FOIG_11948),chromosome unknown,,,,,,2502994,Fusarium odoratissimum,,58,banana Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),AAA,,,Corms; Leaves,small GTPase,,,,reduced virulence,,,,,,reduced,,reduced,reduced,no,NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36012867,PubMed,10.3390/jof8080880,J Fungi (Basel). 2022 Aug 20;8(8):880.,wangzh@fafu.edu.cn,"The banana plantlets inoculated with ΔFoSEC2 showed reduced vegetative growth, vegetative spores and only slightly reduced necrosis symptoms.",Y Zheng 2022,2022,3 genes,Zheng-2022-Small GTPase FoSec4-Mediated Protei,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22578,PHI:124501,UniProt,X0KET6,GenBank,EXM12109,,,54006,Gyp5 (FOIG_01503),chromosome unknown,,,,,,2502994,Fusarium odoratissimum,,58,banana Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),AAA,,,Corms; Leaves,small GTPase,,,,reduced virulence,,,,,,wild type,,reduced,reduced,no,NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36012867,PubMed,10.3390/jof8080880,J Fungi (Basel). 2022 Aug 20;8(8):880.,wangzh@fafu.edu.cn,The banana plantlets inoculated with ΔFoGYP-5 showed reduced vegetative growth and only slightly reduced necrosis symptoms.,Y Zheng 2022,2022,3 genes,Zheng-2022-Small GTPase FoSec4-Mediated Protei,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22579,PHI:124502,UniProt,A0A0I9YG34,GenBank,KLO94966,,,KSU X-10626,Fs00367,,,,,,,42676,Fusarium sacchari,,,pokkah boeng disease,monocots,4547,Saccharum officinarum (related: sugarcane),Zhongzhe 1,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38279852,PubMed,10.1111/mpp.13414,Mol Plant Pathol. 2024 Jan;25(1):e13414,zjisen@126.com; zmuqing@163,ΔFs00367-2 caused smaller spot areas on sugarcane leaves compared to the complemented strains (ΔFs00367-C-1 and ΔFs00367-C-2) and the wild-type strain.,Z Huang 2024,2024,1 gene,Huang-2024-Small secreted effector protein fro,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22580,PHI:124503,UniProt,A0A2K9QF94,GenBank,AUQ25640,,,MS2,ihfA,,,,,,,204042,Dickeya zeae,,MS2,soft rot diseases,monocots,4641,Musa acuminata (related: dwarf banana),,,,Seedlings,integration host factor,,,regulatory pathway,loss of pathogenicity,,,,,no symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35819797,PubMed,10.1111/mpp.13244,Mol Plant Pathol. 2022 Oct;23(10):1487-1507.,jianuanzhou@scau.edu.cn,"""The disease severity of the banana seedlings inoculated with the mutant was ranked ""0"" (symptomless) after 7 days of inoculation, while the banana seedlings inoculated with MS2 and the complemented strains were discoloured. and rotten.""",S Chen 2022,2022,2 genes,Chen-2022-The integration host factor regulate,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22581,PHI:124504,UniProt,A0A2K9QEG0,GenBank,AUQ25329,,,MS2,ihfB,,,,,,,204042,Dickeya zeae,,MS2,soft rot diseases,monocots,4641,Musa acuminata (related: dwarf banana),,,,Seedlings,integration host factor,,,regulatory pathway,loss of pathogenicity,,,,,no symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35819797,PubMed,10.1111/mpp.13244,Mol Plant Pathol. 2022 Oct;23(10):1487-1507.,jianuanzhou@scau.edu.cn,"""The disease severity of the banana seedlings inoculated with the mutant was ranked ""0"" (symptomless) after 7 days of inoculation, while the banana seedlings inoculated with MS2 and the complemented strains were discoloured. and rotten.""",S Chen 2022,2022,2 genes,Chen-2022-The integration host factor regulate,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22582,PHI:124503,UniProt,A0A2K9QF94,GenBank,AUQ25640,,,MS2,ihfA,,,,,,PHI:124504,204042,Dickeya zeae,,MS2,soft rot diseases,monocots,4641,Musa acuminata (related: dwarf banana),,,,Seedlings,integration host factor,,,regulatory pathway,loss of pathogenicity,,,,,no symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35819797,PubMed,10.1111/mpp.13244,Mol Plant Pathol. 2022 Oct;23(10):1487-1507.,jianuanzhou@scau.edu.cn,"""The disease severity of the banana seedlings inoculated with the double mutant was ranked ""0"" (symptomless) after 7 days of inoculation, while the banana seedlings inoculated with MS2 and the complemented strains were discoloured. and rotten.""",S Chen 2022,2022,2 genes,Chen-2022-The integration host factor regulate,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22583,PHI:124504,UniProt,A0A2K9QEG0,GenBank,AUQ25329,,,MS2,ihfB,,,,,,PHI:124503,204042,Dickeya zeae,,MS2,soft rot diseases,monocots,4641,Musa acuminata (related: dwarf banana),,,,Seedlings,integration host factor,,,regulatory pathway,loss of pathogenicity,,,,,no symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35819797,PubMed,10.1111/mpp.13244,Mol Plant Pathol. 2022 Oct;23(10):1487-1507.,jianuanzhou@scau.edu.cn,"""The disease severity of the banana seedlings inoculated with the double mutant was ranked ""0"" (symptomless) after 7 days of inoculation, while the banana seedlings inoculated with MS2 and the complemented strains were discoloured. and rotten.""",S Chen 2022,2022,2 genes,Chen-2022-The integration host factor regulate,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22584,PHI:124503,UniProt,A0A2K9QF94,GenBank,AUQ25640,,,MS2,ihfA,,,,,,,204042,Dickeya zeae,,MS2,soft rot diseases,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,integration host factor,,,regulatory pathway,loss of pathogenicity,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35819797,PubMed,10.1111/mpp.13244,Mol Plant Pathol. 2022 Oct;23(10):1487-1507.,jianuanzhou@scau.edu.cn,The diseased area on the potato slices inoculated with the deletion mutant was much smaller than those slices inoculated with MS2 or the complemented strains.,S Chen 2022,2022,2 genes,Chen-2022-The integration host factor regulate,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22585,PHI:124504,UniProt,A0A2K9QEG0,GenBank,AUQ25329,,,MS2,ihfB,,,,,,,204042,Dickeya zeae,,MS2,soft rot diseases,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,integration host factor,,,regulatory pathway,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35819797,PubMed,10.1111/mpp.13244,Mol Plant Pathol. 2022 Oct;23(10):1487-1507.,jianuanzhou@scau.edu.cn,The diseased area on the potato slices inoculated with the deletion mutant was much smaller than those slices inoculated with MS2 or the complemented strains.,S Chen 2022,2022,2 genes,Chen-2022-The integration host factor regulate,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22586,PHI:124503,UniProt,A0A2K9QF94,GenBank,AUQ25640,,,MS2,ihfA,,,,,,PHI:124504,204042,Dickeya zeae,,MS2,soft rot diseases,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,integration host factor,,,regulatory pathway,loss of pathogenicity,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35819797,PubMed,10.1111/mpp.13244,Mol Plant Pathol. 2022 Oct;23(10):1487-1507.,jianuanzhou@scau.edu.cn,The diseased area on the potato slices inoculated with the double deletion mutant was much smaller than those slices inoculated with MS2 or the complemented strains.,S Chen 2022,2022,2 genes,Chen-2022-The integration host factor regulate,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22587,PHI:124504,UniProt,A0A2K9QEG0,GenBank,AUQ25329,,,MS2,ihfB,,,,,,PHI:124503,204042,Dickeya zeae,,MS2,soft rot diseases,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,integration host factor,,,regulatory pathway,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35819797,PubMed,10.1111/mpp.13244,Mol Plant Pathol. 2022 Oct;23(10):1487-1507.,jianuanzhou@scau.edu.cn,The diseased area on the potato slices inoculated with the double deletion mutant was much smaller than those slices inoculated with MS2 or the complemented strains.,S Chen 2022,2022,2 genes,Chen-2022-The integration host factor regulate,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22588,PHI:124505,UniProt,G4MYD3,GenBank,EHA55268,,,70-15,BIP1 (MGG_08118),,,,,,,318829,Magnaporthe oryzae,,P1.2,rice blast,monocots,4513,Hordeum vulgare (related: barley),Express; Plaisant,,,Leaves,bZip transcription factor,,,,loss of pathogenicity,,,yes,,no lesion,wild type,,wild type,,no,sodium dodecyl sulphate (SDS),sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full ; gene complementation,,,NN,38252628,PubMed,10.1371/journal.ppat.1011945,PLoS Pathog. 2024 Jan 22;20(1):e1011945.,karine.lambou@umontpellier.fr,MGG_08118 deletion mutants were non-pathogenic on barley leaves compared to wild type and complementation.,K Lambou 2024,2024,1 gene,Lambou-2024-The bZIP transcription factor BIP1,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22589,PHI:124505,UniProt,G4MYD3,GenBank,EHA55268,,,70-15,BIP1 (MGG_08118),,,,,,,318829,Magnaporthe oryzae,,P1.2,rice blast,monocots,4530,Oryza sativa (related: rice),Maratelli,,,Leaves,bZip transcription factor,,,,loss of pathogenicity,,,yes,,no lesion,wild type,,wild type,,no,sodium dodecyl sulphate (SDS),sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full ; gene complementation,,,NN,38252628,PubMed,10.1371/journal.ppat.1011945,PLoS Pathog. 2024 Jan 22;20(1):e1011945.,karine.lambou@umontpellier.fr,MGG_08118 deletion mutants were non-pathogenic on rice leaves compared to wild type and complementation.,K Lambou 2024,2024,1 gene,Lambou-2024-The bZIP transcription factor BIP1,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22590,PHI:124506,UniProt,A0A0A2KIK6,GenBank,KGO64155,,,PHI-1,wsc1 (PITC_087410),,,,,,,40296,Penicillium italicum,,PHI-1,green mould,eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruits,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35736129,PubMed,10.3390/jof8060646,J Fungi (Basel). 2022 Jun 20;8(6):646. doi: 10.3390/jof8060646,yszhen@mail.hzau.edu.cn,"The deletion of Piwsc1 resulted in reduced virulence on citrus fruits, as presented by an approximate 57% reduction in the diameter of lesions.",X Li 2022,2022,1 gene,Li-2022-Identification of Pathogenicity-Relate,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22591,PHI:124507,UniProt,G4MW61,GenBank,EHA55021,,,70-15,Swe1 (MGG_01816),chromosome 2,,,MoAtg17; MoAtg18; MoCdc28; MoMps1,UniProt: Q51Y68; GenBank: EHA51796; UniProt: Q524W4; GenBank: EHA50539; UniProt: G4MZ20; Gen,,318829,Magnaporthe oryzae,,70-15,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,WEE protein kinase,,,glycogen metabolism pathway; fatty acid metabolism pathway; autophagy pathway,reduced virulence,,,yes,,fewer lesions,reduced,,reduced,,no,sodium dodecyl sulphate (SDS);Congo red,sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38195499,PubMed,10.1186/s12964-023-01389-6,Cell Commun Signal. 2024 Jan 9;22(1):19,fuchenglin@zju.edu.cn,"The ΔMoswe1 mutant showed reduced vegetative growth, conidiogenesis and fewer lesions than the wild type 70- 15 and the ΔMoswe1-C.",L Li 2024,2024,1 gene,"Li-2024-The cell cycle, autophagy, and cell wa",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22592,PHI:124507,UniProt,G4MW61,GenBank,EHA55021,,,70-15,Swe1 (MGG_01816),chromosome 2,,,MoAtg17; MoAtg18; MoCdc28; MoMps1,UniProt: Q51Y68; GenBank: EHA51796; UniProt: Q524W4; GenBank: EHA50539; UniProt: G4MZ20; Gen,,318829,Magnaporthe oryzae,,70-15,rice blast,monocots,4513,Hordeum vulgare (related: barley),ZJ-8,,,Leaves,WEE protein kinase,,,glycogen metabolism pathway; fatty acid metabolism pathway; autophagy pathway,reduced virulence,,,yes,,fewer lesions,reduced,,reduced,,no,sodium dodecyl sulphate (SDS);Congo red,sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38195499,PubMed,10.1186/s12964-023-01389-6,Cell Commun Signal. 2024 Jan 9;22(1):19,fuchenglin@zju.edu.cn,"The ΔMoswe1 mutant showed reduced vegetative growth, conidiogenesis and fewer lesions than the wild type 70- 15 and the ΔMoswe1-C.",L Li 2024,2024,1 gene,"Li-2024-The cell cycle, autophagy, and cell wa",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22593,PHI:124508,UniProt,X0JK64,GenBank,EXM01593,,,54006,fluG (FOIG_07155),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,glutamine synthetase,,,regulatory pathway,reduced virulence,,,yes,,low disease severity,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔFocfluG mutant was much less than that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22594,PHI:124509,UniProt,X0JFX3,GenBank,EXM00139,,,54006,flbA (FOIG_08170),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,developmental regulator flbA,,,regulatory pathway,reduced virulence,,,yes,,low disease severity,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔFocfluG mutant was much less than that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22595,PHI:124510,UniProt,X0KNZ9,GenBank,EXM10410,,,54006,flbB (FOIG_00530),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,bZip domain-containing protein,,,regulatory pathway,unaffected pathogenicity,,,yes,,wild type,increased,,wild type,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔFocflbB mutant was similar to that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22596,PHI:124511,UniProt,X0LI93,GenBank,EXM08345,,,54006,flbC (FOIG_03036),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,C2H2-type domain-containing protein,,,regulatory pathway,reduced virulence,,,yes,,low disease severity,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔFocflbC mutant was much less than that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22597,PHI:124512,UniProt,X0JMH5,GenBank,EXM02479,,,54006,flbD (FOIG_06682),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,Myb-like DNA-binding protein flbD,,,regulatory pathway,reduced virulence,,,yes,,low disease severity,reduced,,wild type,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔFocflbD mutant was much less than that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22598,PHI:124513,UniProt,X0KSZ8,GenBank,EXM11912,,,54006,abaA-L (FOIG_01396),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,TEA domain-containing protein,,,regulatory pathway,unaffected pathogenicity,,,yes,,wild type,increased,,wild type,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔabaA-L mutant was similar to that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22599,PHI:124514,UniProt,X0KYN9,GenBank,EXM01815,,,54006,wetA-L (FOIG_07289),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,developmental regulatory protein wetA,,,regulatory pathway,unaffected pathogenicity,,,yes,,wild type,increased,,wild type,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔwetA-L mutant was similar to that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22600,PHI:124515,UniProt,X0KYE7,GenBank,EXM01740,,,54006,stuA (FOIG_07247),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,HTH APSES-type domain-containing protein,,,regulatory pathway,reduced virulence,,,yes,,low disease severity,wild type,,reduced,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔFocstuA mutant was much less than that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22601,PHI:124516,UniProt,X0K979,GenBank,EXM10154,,,54006,veA (FOIG_00370),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,velvet factor,,,regulatory pathway,reduced virulence,,,yes,,low disease severity,wild type,,reduced ; defective,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔFocveA mutant was much less than that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22602,PHI:124517,UniProt,X0LP15,GenBank,EXM10295,,,54006,velB (FOIG_00471),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,velvet factor,,,regulatory pathway,reduced virulence,,,yes,,low disease severity,reduced,,reduced ; defective,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔFocvelB mutant was much less than that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22603,PHI:124518,UniProt,X0J4X2,GenBank,EXL91381,,,54006,lae1 (FOIG_15419),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,methyltransferase,,,regulatory pathway,reduced virulence,,,yes,,low disease severity,increased,,wild type ; defective,,no,,,,,,,gene deletion: full,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,Severity of the browning of vascular tissues in the banana plants infectsd with ΔFoclae1 mutant was much less than that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22604,PHI:124519,UniProt,X0JLE9,GenBank,EXL97140,,,54006,medA (FOIG_10811),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,"f. sp. Cubense; Foc TR4, strain 58",Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Cavendish,,,Corms,transcription factor,,,regulatory pathway,increased virulence (hypervirulence),,,yes,,high disease severity,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38276017,PubMed,10.3390/jof10010001,J Fungi (Basel). 2023 Dec 19;10(1):1,gdlufafu@163.com,The disease symptom caused by ΔFocmedA appeared to be much severe than that of the banana plants infected with the wild-type.,S Lu 2023,2023,12 genes,Lu-2023-A Network of Sporogenesis-Responsive G,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22605,PHI:124520,UniProt,A0A8E5MLI1,GenBank,QUC23976,,,UV-8b,STP1 (XP_043001649),chromosome 7,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP1 resulted in similar colony diameters, conidiation and pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22606,PHI:124521,UniProt,A0A063C7D4,GenBank,QUC21641,,,UV-8b,STP3 (XP_042999314),chromosome 4,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,unaffected pathogenicity,,,,,wild type,reduced,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP3 resulted in reduced conidiation, similar colony diameters and pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22607,PHI:124522,UniProt,A0A063C250,GenBank,QUC17017,,,UV-8b,STP5 (XP_042994690),chromosome 7,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP5 resulted in similar colony diameters, conidiation and pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22608,PHI:124523,UniProt,A0A1B5L6A8,GenBank,QUC16891,,,UV-8b,STP7 (XP_042994564),chromosome 1,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP7 resulted in similar colony diameters, conidiation and pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22609,PHI:124524,UniProt,A0A063C6T4,GenBank,QUC20488,,,UV-8b,STP9 (XP_042998161),chromosome 4,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,reduced virulence,,,,,reduced smut balls,reduced,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP9 resulted in similar colony diameters, reduced conidiation and pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22610,PHI:124525,UniProt,A0A063C4U7,GenBank,QUC17337,,,UV-8b,STP11 (XP_042995010),chromosome 1,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,reduced virulence,,,,,reduced smut balls,wild type,,reduced,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP11 resulted in similar conidiation, reduced colony diameter and pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22611,PHI:124526,UniProt,A0A8E5HSM0,GenBank,QUC20758,,,UV-8b,STP14 (XP_042998431),chromosome 4,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP14 resulted in similar colony diameters, conidiation and pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22612,PHI:124527,UniProt,A0A8E5HXH4,GenBank,QUC23450,,,UV-8b,STP20 (XP_043001123),chromosome 7,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP20 resulted in similar colony diameters, conidiation and pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22613,PHI:124528,UniProt,A0A1B5L492,GenBank,QUC22509,,,UV-8b,STP22 (XP_043000182),chromosome 5,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP22 resulted in similar colony diameters, conidiation and pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22614,PHI:124529,UniProt,A0A8E5HWN2,GenBank,QUC22984,,,UV-8b,STP23 (XP_043000657),chromosome 6,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,reduced virulence,,,,,reduced smut balls,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP23 resulted in similar colony diameters, conidiation and reduced pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22615,PHI:124530,UniProt,A0A1B5L755,GenBank,QUC16188,,,UV-8b,STP27 (XP_042993861),chromosome 1,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP27 resulted in similar colony diameters, conidiation and pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22616,PHI:124531,UniProt,A0A8E5MLA3,GenBank,QUC24047,,,UV-8b,STP29 (XP_043001720),chromosome 7,,,,,,1159556,Villosiclava virens,,JZ-11-28,rice false smut,monocots,4530,Oryza sativa (related: rice),WX98; Yongyou 15; IR28,,,spikelet,sugar transporter gene,,,,reduced virulence,,,,,reduced smut balls,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38203770,PubMed,10.3390/ijms25010600,Int J Mol Sci. 2024 Jan 2;25(1):600.,cxluo@mail.hzau.edu.cn,"ΔVvSTP29 resulted in similar colony diameters, conidiation and reduced pathogenicity compared to wild type.",H Qin 2024,2024,12 genes,"Qin-2024-The Identification, Characterization",BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22617,PHI:124532,UniProt,A0A8E5HPZ3,GenBank,QUC19451,,,UV-8b,VelC (UV8b_03692),chromosome 3,,,UvVEA (UV8b_01329),UniProt: A0A8E5MEA6; GenBank: QUC17088,,1159556,Ustilaginoidea virens,,Jt209,rice false smut disease,monocots,4530,Oryza sativa (related: rice),LYP9,,,spikelet,velvet family regulatory protein,,,,loss of pathogenicity,,,,,no smut balls,reduced,,increased,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38240294,PubMed,10.1080/21505594.2023.2301243,Virulence. 2024 Dec;15(1):2301243,liuwende@caas.cn,"Jt209 and CΔUvVELC strains caused the typical symptoms of false smut balls, whereas ΔUvVELC failed to develop false smut balls.",M Yu 2024,2024,2 genes,Yu-2024-UvVelC is important for conidiation an,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22618,PHI:124532,UniProt,A0A8E5HPZ3,GenBank,QUC19451,,,UV-8b,VelC (UV8b_03692),chromosome 3,,,UvVEA (UV8b_01329),UniProt: A0A8E5MEA6; GenBank: QUC17088,PHI:124533,1159556,Ustilaginoidea virens,,Jt209,rice false smut disease,monocots,4530,Oryza sativa (related: rice),LYP9,,,spikelet,velvet family regulatory protein,,,,loss of pathogenicity,,,,,no smut balls,,,increased,,no,,,,,,,gene deletion: full,,,NN,38240294,PubMed,10.1080/21505594.2023.2301243,Virulence. 2024 Dec;15(1):2301243,liuwende@caas.cn,"ΔUvVELC/ ΔUvVEA double mutants behaved almost identically to ΔUvVELC mutants, and completely lost conidiation and pathogenicity.",M Yu 2024,2024,2 genes,Yu-2024-UvVelC is important for conidiation an,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22619,PHI:124533,UniProt,A0A8E5MEA6,GenBank,QUC17088,,,UV-8b,VEA (UV8b_01329),chromosome 1,,,,,PHI:124532,1159556,Ustilaginoidea virens,,Jt209,rice false smut disease,monocots,4530,Oryza sativa (related: rice),LYP9,,,spikelet,velvet family regulatory protein,,,,loss of pathogenicity,,,,,no smut balls,,,increased,,no,,,,,,,gene deletion: full,,,NN,38240294,PubMed,10.1080/21505594.2023.2301243,Virulence. 2024 Dec;15(1):2301243,liuwende@caas.cn,"ΔUvVELC/ ΔUvVEA double mutants behaved almost identically to ΔUvVELC mutants, and completely lost conidiation and pathogenicity.",M Yu 2024,2024,2 genes,Yu-2024-UvVelC is important for conidiation an,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22620,PHI:124534,UniProt,G4NK43,GenBank,EHA46528,,,70-15,Clp1 (MGG_02535),chromosome 7,,,Atg5; Atg7; Atg16; Atg24; Atg28,UniProt: Q525E4; GenBank: EHA57283; UniProt: Q52CS0; GenBank: EHA55718; UniProt: Q520U5; Gen,,318829,Magnaporthe oryzae,,70-15,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,zinc finger PHD-type domain-containing protein,,,,reduced virulence,,,yes,,fewer lesions,increased,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);paraquat;KCl;sodium dodecyl sulphate (SDS);calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;paraquat: CHEBI:34905; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36036638,PubMed,10.1128/spectrum.01021-22,Microbiol Spectr. 2022 Oct 26;10(5):e0102122.,jplu@zju.edu.cn,"Δclp1 displayed reduced hyphal growth and abnormal fungal morphology (including colony, spore, and appressorium), weakened plant infection and decreased virulence.",J Wang 2022,2022,1 gene,Wang-2022-The Plant Homeodomain Protein Clp1 R,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22621,PHI:124534,UniProt,G4NK43,GenBank,EHA46528,,,70-15,Clp1 (MGG_02535),chromosome 7,,,Atg5; Atg7; Atg16; Atg24; Atg28,UniProt: Q525E4; GenBank: EHA57283; UniProt: Q52CS0; GenBank: EHA55718; UniProt: Q520U5; Gen,,318829,Magnaporthe oryzae,,70-15,rice blast,monocots,4513,Hordeum vulgare (related: barley),,,,Leaves,zinc finger PHD-type domain-containing protein,,,,reduced virulence,,,yes,,fewer lesions,increased,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);paraquat;KCl;sodium dodecyl sulphate (SDS);calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;paraquat: CHEBI:34905; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,36036638,PubMed,10.1128/spectrum.01021-22,Microbiol Spectr. 2022 Oct 26;10(5):e0102122.,jplu@zju.edu.cn,"Δclp1 displayed reduced hyphal growth and abnormal fungal morphology (including colony, spore, and appressorium), weakened plant infection and decreased virulence.",J Wang 2022,2022,1 gene,Wang-2022-The Plant Homeodomain Protein Clp1 R,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22622,PHI:124534,UniProt,G4NK43,GenBank,EHA46528,,,70-15,Clp1 (MGG_02535),chromosome 7,clp1ΔPHD,,Atg5; Atg7; Atg16; Atg24; Atg28,UniProt: Q525E4; GenBank: EHA57283; UniProt: Q52CS0; GenBank: EHA55718; UniProt: Q520U5; Gen,,318829,Magnaporthe oryzae,,70-15,rice blast,monocots,4513,Hordeum vulgare (related: barley),,,,Leaves,zinc finger PHD-type domain-containing protein,,,,reduced virulence,,,,,fewer lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,36036638,PubMed,10.1128/spectrum.01021-22,Microbiol Spectr. 2022 Oct 26;10(5):e0102122.,jplu@zju.edu.cn,"The colonial morphology, mycelial growth, and virulence of clp1ΔPHD were comparable with those of Δclp1 and reduced compared to wild type.",J Wang 2022,2022,1 gene,Wang-2022-The Plant Homeodomain Protein Clp1 R,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22623,PHI:124535,UniProt,G2X015,GenBank,EGY21598,,,VdLs.17,PT1 (VDAG_03038),chromosome 6,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Xinluzao 7,,,Seedlings,trehalase,,,,reduced virulence,,,yes,,low disease severity,reduced,,reduced ; defective,reduced,no,sorbitol;NaCl;KCl,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588,,,,,gene deletion: full ; gene complementation,,,NN,38203466,PubMed,10.3390/ijms25010294,Int J Mol Sci. 2023 Dec 25;25(1):294.,sunjie@shzu.edu.cn,The disease index (DI) of cotton plants infected with the two deletion mutants (ΔVdPT1-1 and ΔVdPT1-2) was significantly lower than that of the cotton plants infected with wild-type or ΔVdPT1-C at 18 dpi and 30 dpi.,L Chen 2023,2023,1 gene,Chen-2023-VdPT1 Encoding a Neutral Trehalase o,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22624,PHI:124535,UniProt,G2X015,GenBank,EGY21598,,,VdLs.17,PT1 (VDAG_03038),chromosome 6,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Xinluzao 7,,,Seedlings,trehalase,,,,reduced virulence,,,,,low disease severity,,,reduced ; defective,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,38203466,PubMed,10.3390/ijms25010294,Int J Mol Sci. 2023 Dec 25;25(1):294.,sunjie@shzu.edu.cn,The disease index (DI) of the cotton plants treated with pTRV2-VdPT1 was significantly lower than that of the cotton plants treated with pTRV2-00 at 14 dpi and 21.,L Chen 2023,2023,1 gene,Chen-2023-VdPT1 Encoding a Neutral Trehalase o,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22625,PHI:124536,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaves,histone acetyltransferase,,,,loss of pathogenicity,,,,,no lesion,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35975920,PubMed,10.1128/mbio.01956-22,mBio. 2022 Oct 26;13(5):e0195622.,T20061078@csuft.edu.cn.,"The pathogenicity assays on C. oleifera leaves showed that ΔCfgcn5 caused no lesion, compared to wild type.",S Zhang 2022,2022,3 genes,Zhang-2022-Histone Acetyltransferase CfGcn5-Me,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22626,PHI:124536,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,E129 (glutamic acid) to Q (glutamine),,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaves,histone acetyltransferase,,,,loss of pathogenicity,,,,,no lesion,,,reduced,,no,,,,,,,gene mutation,,,NN,35975920,PubMed,10.1128/mbio.01956-22,mBio. 2022 Oct 26;13(5):e0195622.,T20061078@csuft.edu.cn.,"The pathogenicity assays on C. oleifera leaves showed that E129Q caused no lesion, similar to the ΔCfgcn5 mutant.",S Zhang 2022,2022,3 genes,Zhang-2022-Histone Acetyltransferase CfGcn5-Me,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22627,PHI:124536,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,T167(threonine) and Y168 (tyrosine) to A (alanine),,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaves,histone acetyltransferase,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,35975920,PubMed,10.1128/mbio.01956-22,mBio. 2022 Oct 26;13(5):e0195622.,T20061078@csuft.edu.cn.,The pathogenicity assays on C. oleifera leaves showed that T167AY168A caused lesion that were significantly lesser than those caused by the WT.,S Zhang 2022,2022,3 genes,Zhang-2022-Histone Acetyltransferase CfGcn5-Me,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22628,PHI:124536,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,histone acetyltransferase,,,,loss of pathogenicity,,,,,no lesion,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35975920,PubMed,10.1128/mbio.01956-22,mBio. 2022 Oct 26;13(5):e0195622.,T20061078@csuft.edu.cn.,"The pathogenicity assays on apples showed that ΔCfgcn5 caused no lesion, compared to wild type.",S Zhang 2022,2022,3 genes,Zhang-2022-Histone Acetyltransferase CfGcn5-Me,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22629,PHI:124536,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,E129 (glutamic acid) to Q (glutamine),,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,histone acetyltransferase,,,,loss of pathogenicity,,,,,no lesion,,,reduced,,no,,,,,,,gene mutation,,,NN,35975920,PubMed,10.1128/mbio.01956-22,mBio. 2022 Oct 26;13(5):e0195622.,T20061078@csuft.edu.cn.,"The pathogenicity assays on apples showed that E129Q caused no lesion, similar to the ΔCfgcn5 mutant.",S Zhang 2022,2022,3 genes,Zhang-2022-Histone Acetyltransferase CfGcn5-Me,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22630,PHI:124536,UniProt,L2G9F9,GenBank,MW701426,,,,GCN5,,T167(threonine) and Y168 (tyrosine) to A (alanine),,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,histone acetyltransferase,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,35975920,PubMed,10.1128/mbio.01956-22,mBio. 2022 Oct 26;13(5):e0195622.,T20061078@csuft.edu.cn.,The pathogenicity assays on apples showed that T167AY168A caused lesion that were significantly lesser than those caused by the WT.,S Zhang 2022,2022,3 genes,Zhang-2022-Histone Acetyltransferase CfGcn5-Me,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22631,PHI:124537,UniProt,A0A5B8HG50,GenBank,QDX10245,,,CFLH16,Atg8 (MK622895),,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaves,autophagy-related protein,,,,loss of pathogenicity,,,,,no lesion,,,increased,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35975920,PubMed,10.1128/mbio.01956-22,mBio. 2022 Oct 26;13(5):e0195622.,T20061078@csuft.edu.cn.,ΔCfatg8 mutant showed no lesion compared with the typical and large lesions caused by the WT and the complemented strain on healthy C. oleifera leaves.,S Zhang 2022,2022,3 genes,Zhang-2022-Histone Acetyltransferase CfGcn5-Me,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22632,PHI:124537,UniProt,A0A5B8HG50,GenBank,QDX10245,,,CFLH16,Atg8 (MK622895),,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaves,autophagy-related protein,,,,reduced virulence,,,,,smaller lesions,,,increased,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35975920,PubMed,10.1128/mbio.01956-22,mBio. 2022 Oct 26;13(5):e0195622.,T20061078@csuft.edu.cn.,"On wounded C.oleifera leaves, the ΔCfatg8 mutant showed some lesions than those of the WT and ΔCfatg8/CfATG8.",S Zhang 2022,2022,3 genes,Zhang-2022-Histone Acetyltransferase CfGcn5-Me,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22633,PHI:124538,UniProt,A0A5B8HEH6,GenBank,QDX10246,,,CFLH16,Atg9 (MK622896),,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaves,autophagy-related protein,,,,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35975920,PubMed,10.1128/mbio.01956-22,mBio. 2022 Oct 26;13(5):e0195622.,T20061078@csuft.edu.cn.,"On C. oleifera leaves, ΔCfatg9 mutant exhibited lower virulence than did the WT and ΔCfatg9/CfATG9.",S Zhang 2022,2022,3 genes,Zhang-2022-Histone Acetyltransferase CfGcn5-Me,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22634,PHI:124538,UniProt,A0A5B8HEH6,GenBank,QDX10246,,,CFLH16,Atg9 (MK622896),,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,autophagy-related protein,,,,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35975920,PubMed,10.1128/mbio.01956-22,mBio. 2022 Oct 26;13(5):e0195622.,T20061078@csuft.edu.cn.,"On apples, ΔCfatg9 mutant exhibited lower virulence than did the WT and ΔCfatg9/CfATG9.",S Zhang 2022,2022,3 genes,Zhang-2022-Histone Acetyltransferase CfGcn5-Me,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22635,PHI:124539,UniProt,A0A177D9V1,GenBank,OAG15977,,,SRC1lrK2f,brm1 (XP_018381398.1),chromosome unknown,,,,,,5599,Alternaria alternata,,JT-03,brown spot disease,eudicots,23211,Pyrus communis (related: pear),,,,fruit,scytalone dehydratase,,,,unaffected pathogenicity,,,yes,,wild type,reduced,,wild type ; defective,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38274752,PubMed,10.3389/fmicb.2023.1327765,Front Microbiol. 2024 Jan 11;14:1327765,lyc@gsau.edu.cn,"Compared with WT and ΔAabrm1-C strains, there was no significant difference in lesion diameter of ΔAabrm1 on wound inoculated pear fruit.",R Li 2024,2024,1 gene,Li-2023-Aabrm1-mediated melanin synthesis is e,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22636,PHI:124540,UniProt,G4N2Y0,GenBank,EHA53429,,,70-15,ao1 (MGG_14 307),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39; LTH,,,Leaves,apoplastic ascorbate oxidases,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35799449,PubMed,10.1016/j.molp.2022.07.001,Mol Plant. 2022 Aug 1;15(8):1347-1366.,zhgzhang@njau.edu.cn,Limited numbers of small lesions were observed in rice leaves (CO-39; LTH) infected with the ΔMoao1 mutant compared to complementary and wild type.,J Hu 2022,2022,1 gene,Hu et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22637,PHI:124540,UniProt,G4N2Y0,GenBank,EHA53429,,,70-15,ao1 (MGG_14 307),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),CO-39; LTH,,,Leaves,apoplastic ascorbate oxidases,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35799449,PubMed,10.1016/j.molp.2022.07.001,Mol Plant. 2022 Aug 1;15(8):1347-1366.,zhgzhang@njau.edu.cn,Limited numbers of small lesions were observed in barley leaves infected with the ΔMoao1 mutant compared to complementary and wild type.,J Hu 2022,2022,1 gene,Hu et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22638,PHI:124540,UniProt,G4N2Y0,GenBank,EHA53429,,,70-15,ao1 (MGG_14 307),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),K14,,,Leaves,apoplastic ascorbate oxidases,,,,loss of pathogenicity,,,,,no lesion,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35799449,PubMed,10.1016/j.molp.2022.07.001,Mol Plant. 2022 Aug 1;15(8):1347-1366.,zhgzhang@njau.edu.cn,Absence of lesions were observed in rice leaves (K14) infected with the ΔMoao1 mutant compared to complementary and wild type.,J Hu 2022,2022,1 gene,Hu et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22639,PHI:124540,UniProt,G4N2Y0,GenBank,EHA53429,,,70-15,ao1 (MGG_14 307),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),ZH11,,,Leaves,apoplastic ascorbate oxidases,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,35799449,PubMed,10.1016/j.molp.2022.07.001,Mol Plant. 2022 Aug 1;15(8):1347-1366.,zhgzhang@njau.edu.cn,Limited numbers of small lesions were observed in rice leaves (ZH11) infected with the OE-Moao1 mutant compared to wild type.,J Hu 2022,2022,1 gene,Hu et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22640,PHI:124541,UniProt,A0A2C5W8X0,GenBank,PHH50059,,,CBS 114723,Swi6 (PHH50059),,,,,,,5158,Ceratocystis fimbriata,,BMPZ13,canker stain disease,eudicots,4120,Ipomoea batatas (related: sweet potato),,,,Leaves; root; Seedling,APSES transcription factor,,,cell wall integrity (CWI) pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38295680,PubMed,10.1016/j.micres.2024.127624,Microbiol Res. 2024 Apr;281:127624.,lilianwei77@126.com,"Deletion of CfSWI6 leads to impaired hyphal development, conidiation, and compromised cell wall integrity, resulting in a significant reduction in virulence.",H Cong 2024,2024,1 gene,Cong et al 2024,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22641,PHI:124542,UniProt,G4N598,GenBank,EHA52156,,,70-15,Tom20 (MGG_06097),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,translocase of outer membrane,,,,reduced virulence,,,yes,,,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38171376,PubMed,10.1094/MPMI-10-23-0168-R,Mol Plant Microbe Interact. 2024 Jan 3.,hfzhang@njau.edu.cn,"The growth rate, conidial production and pathogenicity are decreased in the ΔMotom20 mutant compared to that in the wild type and complemented strains.",S Wu 2024,2024,1 gene,Wu et al 2024,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22642,PHI:124543,UniProt,A0A194VQ59,GenBank,KUI66122,,,03-8,Mon1 (KUI66122.1),chromosome 2,,,Ccz1 (KUI74328.1); VmRab5AQ71L (active); VmRab5BQ78L (active); VmRab7; VmRab7T22N (inactive); VmRab7Q67L (active),UniProt: A0A194WDX9; GenBank: KUI74328; UniProt: A0A194W1D6; GenBank: KUI70279; UniProt: A0A,,105487,Valsa mali,,03-8,apple Valsa canker,eudicot,3750,Malus domestica (related: apple),Fuji,,,Leaves; Twigs,monensin sensitivity 1 protein,,,autophagy pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT);monensin;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170; ;monensin: CHEBI:27617; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,35793146,PubMed,10.1094/MPMI-03-22-0071-R,Mol Plant Microbe Interact. 2022 Oct;35(10):906-916.,liangsheng.xu@nwafu.edu.cn,"Targeted gene deletion showed that the VmMon1 mutant were defective in vegetative growth, conidiation, and pathogenicity.",L Xu 2022,2022,2 genes,Xu et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22643,PHI:124544,UniProt,A0A194WDX9,GenBank,KUI74328,,,03-8,Ccz1 (KUI74328.1),chromosome 12,,,Atg8 (VM1G_03287); VmRab5AQ71L (active); VmRab5BQ78L (active); VmRab7; VmRab7T22N (inactive); VmRab7Q67L (active),UniProt: A0A194VV27; GenBank: KUI67852; UniProt: A0A194W1D6; GenBank: KUI70279; UniProt: A0A,,105487,Valsa mali,,03-8,apple Valsa canker,eudicot,3750,Malus domestica (related: apple),Fuji,,,Leaves; Twigs,"caffeine, calcium, and zinc sensitivity 1 protein",,,autophagy pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT);monensin;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170; ;monensin: CHEBI:27617; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,35793146,PubMed,10.1094/MPMI-03-22-0071-R,Mol Plant Microbe Interact. 2022 Oct;35(10):906-916.,liangsheng.xu@nwafu.edu.cn,"Targeted gene deletion showed that the VmCcz1 mutant were defective in vegetative growth, conidiation, and pathogenicity.",L Xu 2022,2022,2 genes,Xu et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22644,PHI:124543,UniProt,A0A194VQ59,GenBank,KUI66122,,,03-8,Mon1 (KUI66122.1),chromosome 2,,,Ccz1 (KUI74328.1); VmRab5AQ71L (active); VmRab5BQ78L (active); VmRab7; VmRab7T22N (inactive); VmRab7Q67L (active),UniProt: A0A194WDX9; GenBank: KUI74328; UniProt: A0A194W1D6; GenBank: KUI70279; UniProt: A0A,PHI:124544,105487,Valsa mali,,03-8,apple Valsa canker,eudicot,3750,Malus domestica (related: apple),Fuji,,,Leaves; Twigs,monensin sensitivity 1 protein,,,autophagy pathway,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35793146,PubMed,10.1094/MPMI-03-22-0071-R,Mol Plant Microbe Interact. 2022 Oct;35(10):906-916.,liangsheng.xu@nwafu.edu.cn,"Targeted double gene deletion showed that the VmMon1/VmCcz1 mutant were defective in vegetative growth, and pathogenicity.",L Xu 2022,2022,2 genes,Xu et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22645,PHI:124544,UniProt,A0A194WDX9,GenBank,KUI74328,,,03-8,Ccz1 (KUI74328.1),chromosome 12,,,Atg8 (VM1G_03287); VmRab5AQ71L (active); VmRab5BQ78L (active); VmRab7; VmRab7T22N (inactive); VmRab7Q67L (active),UniProt: A0A194VV27; GenBank: KUI67852; UniProt: A0A194W1D6; GenBank: KUI70279; UniProt: A0A,PHI:124543,105487,Valsa mali,,03-8,apple Valsa canker,eudicot,3750,Malus domestica (related: apple),Fuji,,,Leaves; Twigs,"caffeine, calcium, and zinc sensitivity 1 protein",,,autophagy pathway,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35793146,PubMed,10.1094/MPMI-03-22-0071-R,Mol Plant Microbe Interact. 2022 Oct;35(10):906-916.,liangsheng.xu@nwafu.edu.cn,"Targeted double gene deletion showed that the VmMon1/VmCcz1 mutant were defective in vegetative growth, and pathogenicity.",L Xu 2022,2022,2 genes,Xu et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22646,PHI:124545,UniProt,A0A7T6XTE7,GenBank,QQK46930,,,PdW03,atfA (QQK46930),chromosome 5,,,,,,36651,Penicillium digitatum,,Pd01 (CBS130525),green mould,eudicots,2711,Citrus sinensis (related: sweet orange),,,,fruits,bZip transcription factor,,,,unaffected pathogenicity,,,,,wild type,wild type,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;fludioxonil;iprodione;Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;fludioxonil: CHEBI:81763; ;iprodione: CHEBI:28909; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,35868518,PubMed,10.1016/j.resmic.2022.103970,Res Microbiol. 2022 Oct-Dec;173(8):103970.,mswang@hznu.edu.cn,ΔPdatfA mutant displayed reduced vegetative growth and similar rot symptoms to that of the wild-type.,X Luo 2022,2022,1 gene,Luo et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22647,PHI:124546,UniProt,W7LFX0,GenBank,EWG38333,,,7600,Lcp1 (FVEG_01584),chromosome 6,,,,,,117187,Fusarium verticillioides,334819,7600,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,secreted protein,,,,unaffected pathogenicity,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36126492,PubMed,10.1016/j.micres.2022.127195,Microbiol Res. 2022 Dec;265:127195.,huanzhfly0301@email.tamu.edu,When pathogenicity is tested we did not observe a significant difference between wild type and mutant strain.,H Zhang 2022,2022,1 gene,Zhang et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22648,PHI:124546,UniProt,W7LFX0,GenBank,EWG38333,,,7600,Lcp1 (FVEG_01584),chromosome 6,,,,,,117187,Fusarium verticillioides,334819,7600,maize ear rot,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,secreted protein,,,,unaffected pathogenicity,,,yes,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,36126492,PubMed,10.1016/j.micres.2022.127195,Microbiol Res. 2022 Dec;265:127195.,huanzhfly0301@email.tamu.edu,When pathogenicity is tested we did not observe a significant difference between wild type and mutant strain.,H Zhang 2022,2022,1 gene,Zhang et al 2022,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22649,PHI:124547,UniProt,A0A0K0GKR3,GenBank,ACD58962,,,PXO99A,TrpR (PXO_00831),,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24,,,Leaves,putative trpR-like protein,,,trp biosynthesis pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,36095334,PubMed,10.1094/PHYTO-05-22-0165-R,Phytopathology. 2023 Feb;113(2):170-182.,fqliu20011@sina.com,The average lesion length in rice leaves caused by the ΔPXO_trpR strain was significantly reduced at 7 and 14 days compared to complementation and wild type.,Z Xu 2023,2023,1 gene,Xu et al 2023,BATCH_130,2024-02-01,MC,,,,,,,,,,,,,
,,Record 22650,PHI:124548,UniProt,A0A0F7SCY3,GenBank,CDU24191,,,SscI8,SsCI80130 (CDU24191.1),,,,,,,49012,Sporisorium scitamineum,,Ss16,sugarcane smut,monocots,4547,Saccharum officinarum (related: sugarcane),ROC22,,,Seedlings,squalene monooxygenase gene,,,ergosterol synthesis pathway,reduced virulence,,,,,,,,reduced,,no,hydrogen peroxide (H2O2);2-benzoxazolinone;3-furancarboxaldehyde (3FCA);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;2-benzoxazolinone CAS no.: CAS:59-49-4; ;3-furancarboxaldehyde (3FCA) CAS: CAS:498-60-2; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,35628726,PubMed,10.3390/jof8050470,J Fungi (Basel). 2022 Apr 30;8(5):470.,wkshen69@126.com,"Knockout mutants (ΔSs80130+ + ΔSs80130−, Ss16+ + ΔSs80130−, or Ss16− + ΔSs80130+), cane plants displayed significantly lower incidence.",Y Cai 2022,2022,1 gene,Cai-2022-Squalene Monooxygenase Gene SsCI80130,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22651,PHI:124549,UniProt,A4R2Z0,GenBank,EHA56556,,,70-15,Pex22 (MGG_02391),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,peroxin 22-like protein,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38392815,PubMed,10.3390/jof10020143,J Fungi (Basel). 2024 Feb 10;10(2):143.,jhjiang@jsnu.edu.cn,"The ΔMopex22 mutant exhibited slow growth, reduced aerial hyphae, and almost complete loss of virulence.",R Chen 2024,2024,1 gene,Chen-2024-Peroxin MoPex22 Regulates the Import,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22652,PHI:124550,UniProt,D4I437,GenBank,CBA20974,,,CFPB1430,proQ,,,,,,,552,Erwinia amylovora,,1189,fire blight,eudicots,3750,Malus domestica (related: apple),Gala,,,Shoots,RNA chaperone,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35416685,PubMed,10.1128/aem.00239-22,Appl Environ Microbiol. 2022 May 10;88(9):e0023922.,sundin@msu.edu.,"Significant reduction in disease progression in shoots inoculated with Ea1189 ΔproQ, with an average ratio of lesion/shoot length of approximately 7%, relative to a 28% ratio in shoots inoculated with WT Ea1189.",X Yuan 2022,2022,1 gene,Yuan-2022-The RNA-Binding Protein ProQ Impacts,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22653,PHI:124551,UniProt,A0A8E5HK60,GenBank,QUC16793,,,UV-8b,Hos3 (XP_042994466.1),chromosome 1,,,,,,1159556,Ustilaginoidea virens,,P1,rice false smut disease,monocots,4530,Oryza sativa (related: rice),LYP9,,,Panicles,histone deacetylases,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38353606,PubMed,10.1111/mpp.13429,Mol Plant Pathol. 2024 Feb;25(2):e13429.,wxs@cau.edu.cn,"The ΔUvhos3 deletion mutant exhibited the phenotypes of retarded growth, increased mycelial branches and reduced conidiation and virulence.",B Wang 2024,2024,1 gene,Wang-2024-UvHOS3-mediated histone deacetylatio,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22654,PHI:124552,UniProt,A0A1D9QGD8,GenBank,APA14016,,,1980,ZNC1 (sscle_12g087860),chromosome 12,,,,,,5180,Sclerotinia sclerotiorum,665079,1980 (ATCC 18683),white mould,eudicots,3708,Brassica napus (related: rape),,,,Leaves,transcription factor,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,NaCl;sodium dodecyl sulphate (SDS);Congo red,NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38392807,PubMed,10.3390/jof10020135,J Fungi (Basel). 2024 Feb 8;10(2):135.,jiasencheng@mail.hzau.edu.cn,The target deletion of SsZNC1 resulted in reduced virulence on oilseed rape.,Y Huang 2024,2024,1 gene,Huang-2024-The Transcription Factor SsZNC1 Med,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22655,PHI:124552,UniProt,A0A1D9QGD8,GenBank,APA14016,,,1980,ZNC1 (sscle_12g087860),chromosome 12,,,,,,5180,Sclerotinia sclerotiorum,665079,1980 (ATCC 18683),white mould,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,Leaves,transcription factor,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,NaCl;sodium dodecyl sulphate (SDS);Congo red,NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38392807,PubMed,10.3390/jof10020135,J Fungi (Basel). 2024 Feb 8;10(2):135.,jiasencheng@mail.hzau.edu.cn,The target deletion of SsZNC1 resulted in reduced virulence on Arabidopsis.,Y Huang 2024,2024,1 gene,Huang-2024-The Transcription Factor SsZNC1 Med,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22656,PHI:124553,UniProt,A9CJK8,GenBank,AAK86834,,,C58,atu1027 (WP_010971342.1),chromosome circular,,,CheW1; CheW2,UniProt: A0A1S7SZV8; GenBank: CVI18876; UniProt: A0A1S7SZD2; GenBank: CVI18878,,358,Agrobacterium tumefaciens,176299,C58,crown gall disease,eudicots,23013,Arabidopsis thaliana (related: thale cress),,,,Leaves,cytoplasmic chemoreceptor,,,,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38332807,PubMed,10.7717/peerj.16898,PeerJ. 2024 Feb 5;12:e16898.,huangzhiwei@hyit.edu.cn,The tumour induced by the C58Δ11027 was smaller compared to those induced by the C58 and C58 11027+.,Z Huang 2024,2024,1 gene,Huang-2024-An aerotaxis receptor influences in,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22657,PHI:124554,UniProt,A0A2K9QIX2,GenBank,AUQ26891,,,MS2,Hfq (WP_012886271),,,,,,,1240404,Dickeya oryzae,,EC1,soft rot diseases,eudicot,4113,Solanum tuberosum (related: potato),,,,tuber,RNA chaperone protein,,,,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35630473,PubMed,10.3390/microorganisms10051031,Microorganisms. 2022 May 16;10(5):1031.,lhzhang01@scau.edu.cn,Potato tuber slices inoculated with the hfqEC1 mutant had substantially reduced rotting areas compared with those inoculated with the wild-type strain EC1 at 48 h post-inoculation.,Z Shi 2022,2022,1 gene,Shi-2022-Hfq Is a Critical Modulator of Pathog,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22658,PHI:124554,UniProt,A0A2K9QIX2,GenBank,AUQ26891,,,MS2,Hfq (WP_012886271),,,,,,,1240404,Dickeya oryzae,,EC1,soft rot diseases,monocot,4530,Oryza sativa (related: rice),CO39,,,Seeds,RNA chaperone protein,,,,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35630473,PubMed,10.3390/microorganisms10051031,Microorganisms. 2022 May 16;10(5):1031.,lhzhang01@scau.edu.cn,The wild-type strain EC1 was much more virulent than the hfqEC1 mutant on rice seed germination.,Z Shi 2022,2022,1 gene,Shi-2022-Hfq Is a Critical Modulator of Pathog,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22659,PHI:124555,UniProt,A0A364MZC1,GenBank,RAR07649,,,CIDEFI 213,NLP,,,,,,,183478,Stemphylium lycopersici,,,grey leaf spot disease,eudicots,4081,Solanum lycopersicum (related: tomato),M82,,,Leaves,Nep1-like protein,,,,reduced virulence,,,,,smaller lesions,reduced,,wild type,wild type,no,hydrogen peroxide (H2O2);NaCl;KCl,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588,,,,,gene deletion: full ; gene complementation,,,NN,35628773,PubMed,10.3390/jof8050518,J Fungi (Basel). 2022 May 18;8(5):518.,zhaojiuhai@iga.ac.cn,nlp mutant leads to reduced conidia and virulence and there was no significant difference in mycelial growth.,J Lian 2022,2022,1 gene,Lian-2022-Stemphylium lycopersici Nep1-like Pr,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22660,PHI:124556,UniProt,G2WV90,GenBank,EGY20215,,,VdLs.17,FAE (XP_009656555),chromosome 7,,,,,,27337,Verticillium dahliae,,XJ592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Jimian 11,,,Seedlings,feruloyl esterase,,,,reduced virulence,,,,,smaller necrotic area,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38353627,PubMed,10.1111/mpp.13431,Mol Plant Pathol. 2024 Feb;25(2):e13431.,qinj@nwafu.edu.cn,"The seedlings inoculated with the WT strain XJ592 and the complementary strain showed much more severe symptoms of wilting, leaf necrosis and even premature defoliation than those inoculated with ΔVdFAE at 20 dpi.",Y Wang 2024,2024,1 gene,Wang-2024-The secreted feruloyl esterase of Ve,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22661,PHI:124556,UniProt,G2WV90,GenBank,EGY20215,,,VdLs.17,FAE (XP_009656555),chromosome 7,,,,,,27337,Verticillium dahliae,,XJ592,vascular wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,Seedlings,feruloyl esterase,,,,reduced virulence,,,,,smaller necrotic area,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38353627,PubMed,10.1111/mpp.13431,Mol Plant Pathol. 2024 Feb;25(2):e13431.,qinj@nwafu.edu.cn,"The seedlings inoculated with the WT strain XJ592 and the complementary strain showed much more severe symptoms of wilting, leaf necrosis and even premature defoliation than those inoculated with ΔVdFAE at 20 dpi.",Y Wang 2024,2024,1 gene,Wang-2024-The secreted feruloyl esterase of Ve,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22662,PHI:124557,UniProt,G2XA37,GenBank,EGY15776,,,VdLs.17,PBP1,chromosome 5,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),MoneyMaker,,,Seedlings; stem,transcription factor,,,,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full,,,NN,38399669,PubMed,10.3390/microorganisms12020265,Microorganisms. 2024 Jan 26;12(2):265.,buitrithuc@tuaf.edu.vn,"Tomato plants infected with the wild type exhibited a high percentage of disease index, reaching 81.67%, while uninfected plants (Mock) and plants infected with the VdPBP1 mutant had percentages of disease indices of 1.6% and 20%.",H T Nguyen 2024,2024,1 gene,Nguyen-2024-Verticillium dahliae VdPBP1 Transc,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22663,PHI:124558,UniProt,A0A9P7RDT1,GenBank,KAG7055400,,,Coll-153,Pom1,,,,,,,1209932,Colletotrichum scovillei,,KC05,anthracnose,eudicot,4072,Capsicum annuum (no common name found),Gilsang,,,fruit,dual-specificity tyrosine phosphorylation-regulated kinase,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,wild type,no,NaCl;KCl,NaCl: CHEBI:26710; ;KCl: CHEBI:32588,,,,,gene deletion: full ; gene complementation,,,NN,35558103,PubMed,10.3389/fcimb.2022.861915,Front Cell Infect Microbiol. 2022 Apr 26;12:861915.,kims@kangwon.ac.kr,"Cspom1 mutant exhibited a reduction in vegetative growth, conidiation and delayed penetration and invasive growth, leading to significantly reduced virulence.",J H Shin 2022,2022,1 gene,"Shin-2022-CsPOM1, a DYRK Family Kinase, Plays",BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22664,PHI:124559,UniProt,W7M9G9,GenBank,EWG41554,,,7600,Kex2 (FVEG_03645),chromosome 2,,,,,,117187,Fusarium verticillioides,334819,7600 (A149),maize ear rot,monocot,4577,Zea mays (related: maize),B73,,,Stalk,kexin-like golgi-resident proprotein,,,,reduced virulence,,,,,no lesion,reduced,wild type,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38386129,PubMed,10.1007/s00253-024-13022-8,Appl Microbiol Biotechnol. 2024 Feb 22;108(1):228.,wbshim@tamu.edu,ΔFvkex2 mutant could not develop any significant stalk rot lesion on the stalk tissues in comparison with the wildtype and the complemented strain,L Wu 2024,2024,1 gene,"Wu-2024-FvKex2 is required for development, vi",BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22665,PHI:124559,UniProt,W7M9G9,GenBank,EWG41554,,,7600,Kex2 (FVEG_03645),chromosome 2,,,,,,117187,Fusarium verticillioides,334819,7600 (A149),maize ear rot,monocot,4547,Saccharum officinarum (related: sugarcane),,,,Leaves,kexin-like golgi-resident proprotein,,,,reduced virulence,,,,,no lesion,reduced,wild type,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38386129,PubMed,10.1007/s00253-024-13022-8,Appl Microbiol Biotechnol. 2024 Feb 22;108(1):228.,wbshim@tamu.edu,ΔFvkex2 mutant failed to develop any observable sugarcane leaf blight symptoms as seen on the leaves infected with the wild-type and complemented strains.,L Wu 2024,2024,1 gene,"Wu-2024-FvKex2 is required for development, vi",BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22666,PHI:124560,UniProt,Q48J97,GenBank,AAZ37819,,,1448A; BAA-978,gacA,,,,,,,29438,Pseudomonas savastanoi,693985,NCPPB 3335,olive knot,eudicot,4146,Olea europaea (related: common olive),Arbequina,,,Seedling,regulator,,,,increased virulence (hypervirulence),,,,,high disease severity,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,38375080,PubMed,10.3389/fpls.2024.1347982,Front Plant Sci. 2024 Feb 5;15:1347982.,lgrodriguez@uma.es,Tumours induced by strain Psv-ΔgacA and the complemented strain Psv::uvrC were noticeably bigger than tumours induced by strains NCPPB 3335.,C Lavado-Benito 2024,2024,1 gene,Lavado-Benito-2024-GacA reduces virulence and,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22667,PHI:124561,UniProt,E3QMF3,GenBank,EFQ32041,,,M1.001,UGE1 gene (GLRG_07185),,,,,,,31870,Colletotrichum graminicola,,M2,stalk rot and leaf blight of maize,monocot,4577,Zea mays (related: maize),Mikado,,,Leaves,galactose metabolism gene,,,galactomannan biosynthesis pathway,reduced virulence,,,yes,,low disease severity,,,reduced,,no,sucrose;glucose,sucrose: CHEBI:17992; ;glucose: CHEBI:17234,,,,,gene deletion: full,,,NN,38400525,PubMed,10.1111/mmi.15242,Mol Microbiol. 2024 Feb 23.,holger.deising@landw.uni-halle.de,Only minor disease symptoms occurred on leaves inoculated with Δuge1 compared to wild type.,M Groß 2024,2024,2 genes,Gro? et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22668,PHI:124562,UniProt,E3QMT3,GenBank,EFQ32171,,,M1.001,UGM1 gene (GLRG_07315),,,,,,,31870,Colletotrichum graminicola,,M2,stalk rot and leaf blight of maize,monocot,4577,Zea mays (related: maize),Mikado,,,Leaves,galactose metabolism gene,,,galactomannan biosynthesis pathway,reduced virulence,,,yes,,low disease severity,,,reduced,,no,sucrose;glucose,sucrose: CHEBI:17992; ;glucose: CHEBI:17234,,,,,gene deletion: full,,,NN,38400525,PubMed,10.1111/mmi.15242,Mol Microbiol. 2024 Feb 23.,holger.deising@landw.uni-halle.de,Only minor disease symptoms occurred on leaves inoculated with Δugm1 compared to wild type.,M Groß 2024,2024,2 genes,Gro? et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22669,PHI:124563,UniProt,A0A8S9DJX6,GenBank,KAE9582906,,,CGMCC3.17371,Mcm1 (XP_031892453.1),,,,,,,690256,Colletotrichum fructicola,,1104-6,anthracnose,eudicots,3750,Malus domestica (related: apple),Gala,,,Leaves,transcription factor,,,melanin biosynthesis pathway,loss of pathogenicity,,,yes,,no lesion,reduced,reduced,reduced,reduced,no,hydrogen peroxide (H2O2);KCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,35502927,PubMed,10.1094/PHYTO-03-22-0090-R,Phytopathology. 2022 Oct;112(10):2159-2173.,rongzh@nwsuaf.edu.cn,The gene deletion mutant CfMcm1 lost pathogenicity to apple leaves.,W Liu 2022,2022,1 gene,Liu et al 2022,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22670,PHI:124563,UniProt,A0A8S9DJX6,GenBank,KAE9582906,,,CGMCC3.17371,Mcm1 (XP_031892453.1),,,,,,,690256,Colletotrichum fructicola,,1104-6,anthracnose,eudicots,3750,Malus domestica (related: apple),Gala,,,fruit,transcription factor,,,melanin biosynthesis pathway,reduced virulence,,,yes,,no lesion,reduced,reduced,reduced,reduced,no,hydrogen peroxide (H2O2);KCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,35502927,PubMed,10.1094/PHYTO-03-22-0090-R,Phytopathology. 2022 Oct;112(10):2159-2173.,rongzh@nwsuaf.edu.cn,"At 7 dpi, the lesion diameter on wounded apple fruit caused by CfMcm mutant was only 49% that of the WT.",W Liu 2022,2022,1 gene,Liu et al 2022,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22671,PHI:124564,UniProt,A0A0J9USF5,GenBank,KNB01181,,,4287,FLP1 (XP_018239226.1),chromosome 4,,,,,,5507,Fusarium oxysporum,,,Fusarium wilt,eudicot,4081,Solanum lycopersicum (related: tomato),Pusa Early Dwarf; Pusa Ruby,,,fruit; Seedlings,fasciclin-like protein,,,,reduced virulence,,,,,low disease severity,increased,,increased,,no,,,,,,,gene deletion: full,,,NN,35487139,PubMed,10.1016/j.micres.2022.127033,Microbiol Res. 2022 Jul;260:127033.,rajam.mv@gmail.com,The seedlings infected with FLP 1 showed late onset of disease with low disease severity index compared to non-transformant (WT).,S Chauhan 2022,2022,4 genes,Chauhan et al 2022,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22672,PHI:124565,UniProt,A0A0J9UJL5,GenBank,KNA99379,,,4287,FLP3 (XP_018237425.1),chromosome 8,,,,,,5507,Fusarium oxysporum,,,Fusarium wilt,eudicot,4081,Solanum lycopersicum (related: tomato),Pusa Early Dwarf; Pusa Ruby,,,fruit; Seedlings,fasciclin-like protein,,,,reduced virulence,,,,,low disease severity,increased,,increased,,no,,,,,,,gene deletion: full,,,NN,35487139,PubMed,10.1016/j.micres.2022.127033,Microbiol Res. 2022 Jul;260:127033.,rajam.mv@gmail.com,The seedlings infected with FLP 3 showed late onset of disease with low disease severity index compared to non-transformant (WT).,S Chauhan 2022,2022,4 genes,Chauhan et al 2022,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22673,PHI:124566,UniProt,A0A0J9WI37,GenBank,KNA97851,,,4287,FLP4 (XP_018235897.1),chromosome 5,,,,,,5507,Fusarium oxysporum,,,Fusarium wilt,eudicot,4081,Solanum lycopersicum (related: tomato),Pusa Early Dwarf; Pusa Ruby,,,fruit; Seedlings,fasciclin-like protein,,,,reduced virulence,,,,,low disease severity,increased,,increased,,no,,,,,,,gene deletion: full,,,NN,35487139,PubMed,10.1016/j.micres.2022.127033,Microbiol Res. 2022 Jul;260:127033.,rajam.mv@gmail.com,The seedlings infected with FLP 4 showed late onset of disease with low disease severity index compared to non-transformant (WT).,S Chauhan 2022,2022,4 genes,Chauhan et al 2022,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22674,PHI:124567,UniProt,A0A0J9WL22,GenBank,KNB03027,,,4287,FLP5 (XP_018241072.1),chromosome 2a,,,,,,5507,Fusarium oxysporum,,,Fusarium wilt,eudicot,4081,Solanum lycopersicum (related: tomato),Pusa Early Dwarf; Pusa Ruby,,,fruit; Seedlings,fasciclin-like protein,,,,reduced virulence,,,,,low disease severity,increased,,increased,,no,,,,,,,gene deletion: full,,,NN,35487139,PubMed,10.1016/j.micres.2022.127033,Microbiol Res. 2022 Jul;260:127033.,rajam.mv@gmail.com,The seedlings infected with FLP 5 showed late onset of disease with low disease severity index compared to non-transformant (WT).,S Chauhan 2022,2022,4 genes,Chauhan et al 2022,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22675,PHI:124568,UniProt,E4ZUN5,GenBank,CBX95114,,,,Pf2 (XP_003838593.1),,,,,,,5022,Leptosphaeria maculans,,JN2,stem canker of oilseed rape,eudicot,3708,Brassica napus (related: rape),,,,Cotyledons,effector protein,,,,effector (plant avirulence determinant),,,,,no disease,reduced,,reduced ; defective,,no,,,,,,,gene deletion: full,,,NN,38358035,PubMed,10.1111/nph.19581,New Phytol. 2024 Feb 15.,jessica.soyer@inrae.fr,The ΔLmPf2 mutant was not able to invade the cotyledon further than the inoculation site and did not induce any visible symptoms.,C Clairet 2024,2024,1 gene,Clairet et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22676,PHI:124568,UniProt,E4ZUN5,GenBank,CBX95114,,,,Pf2 (XP_003838593.1),,,,,,,5022,Leptosphaeria maculans,,JN2,stem canker of oilseed rape,eudicot,3708,Brassica napus (related: rape),,,,Cotyledons,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,increased,,reduced ; defective,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,38358035,PubMed,10.1111/nph.19581,New Phytol. 2024 Feb 15.,jessica.soyer@inrae.fr,The LmPf2 overexpression mutant showed reduced symptoms compared with the WT.,C Clairet 2024,2024,1 gene,Clairet et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22677,PHI:124569,UniProt,A0A4T0WF76,GenBank,TID04738,,,MAFF305635-RFP,Cte1 (CH35J_003317),,,,,,,1209068,Colletotrichum tabacum,,YC1,anthracnose,eudicot,4100,Nicotiana benthamiana (no common name found),,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,increased,,increased,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38377033,PubMed,10.1094/MPMI-11-23-0197-R,Mol Plant Microbe Interact. 2024 Feb 20.,zhangjunxiang@caas.cn,The CTE1 knockout mutants decrease the virulence of C. tabacum to N. benthamiana.,X Yuan 2024,2024,1 gene,Xue et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22678,PHI:124570,UniProt,A0A177DFP3,GenBank,OAG17990,,,SRC1lrK2f,PLC1 (XP_018383411.1),chromosome unknown,,,,,,5599,Alternaria alternata,,KY397985.1,brown spot disease,eudicot,225117,Pyrus bretchneideri (related: chinese white pear),Zaosu,,,fruit,phospholipase C,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,35612304,PubMed,10.1094/PHYTO-11-21-0475-R,Phytopathology. 2022 Oct;112(10):2207-2217.,lyc@gsau.edu.cn,AaPLC1 mutant exhibited 35.6% reduction in virulence at 7 days postinoculation compared to complementary and WT.,Y Huang 2022,2022,3 genes,Huang et al 2022,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22679,PHI:124571,UniProt,A0A177D8R6,GenBank,OAG15916,,,SRC1lrK2f,PLC2 (XP_018381337.1),chromosome unknown,,,,,,5599,Alternaria alternata,,KY397985.1,brown spot disease,eudicot,225117,Pyrus bretchneideri (related: chinese white pear),Zaosu,,,fruit,phospholipase C,,,,unaffected pathogenicity,,,yes,,wild type,reduced,,reduced ; defective,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,35612304,PubMed,10.1094/PHYTO-11-21-0475-R,Phytopathology. 2022 Oct;112(10):2207-2217.,lyc@gsau.edu.cn,AaPLC2 mutant exhibited identical lesion extension as complementary and WT.,Y Huang 2022,2022,3 genes,Huang et al 2022,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22680,PHI:124572,UniProt,A0A177DTV1,GenBank,OAG23175,,,SRC1lrK2f,PLC3 (XP_018388596.1),chromosome unknown,,,,,,5599,Alternaria alternata,,KY397985.1,brown spot disease,eudicot,225117,Pyrus bretchneideri (related: chinese white pear),Zaosu,,,fruit,phospholipase C,,,,unaffected pathogenicity,,,yes,,wild type,reduced,,reduced,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,35612304,PubMed,10.1094/PHYTO-11-21-0475-R,Phytopathology. 2022 Oct;112(10):2207-2217.,lyc@gsau.edu.cn,AaPLC3 mutant exhibited identical lesion extension as complementary and WT.,Y Huang 2022,2022,3 genes,Huang et al 2022,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22681,PHI:124573,UniProt,A0A0D1E411,GenBank,KIS70839,,,521,pep1 (UMAG_01987),chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,no disease,,,reduced,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The complete loss of virulence was seen for mutants lacking pep1 mutant.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22682,PHI:124574,UniProt,A0A0D1CU07,GenBank,KIS69963,,,521,stp1 (UMAG_02475),chromosome 5,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,no disease,,,reduced,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The complete loss of virulence was seen for mutants lacking stp1 mutant.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22683,PHI:124575,UniProt,A0A0D1E167,GenBank,KIS69651,,,521,stp2 (UMAG_10067),chromosome 5,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,no disease,,,reduced,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The complete loss of virulence was seen for mutants lacking stp2 mutant.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22684,PHI:124576,UniProt,A0A0D1EAN2,GenBank,KIS72306,,,521,stp3 (UMAG_00715),chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,no disease,,,reduced,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The complete loss of virulence was seen for mutants lacking stp3 mutant.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22685,PHI:124577,UniProt,A0A0D1C5E3,GenBank,KIS68887,,,521,stp4 (UMAG_12197),chromosome 7,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,no disease,,,reduced,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The complete loss of virulence was seen for mutants lacking stp4 mutant.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22686,PHI:124578,UniProt,A0A0D1EAR7,GenBank,KIS71480,,,521,pit2 (UMAG_01375),chromosome 2,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,no disease,,,reduced,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The complete loss of virulence was seen for mutants lacking pit2 mutant.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22687,PHI:124579,UniProt,A0A0D1C8C8,GenBank,KIS69712,,,521,see1 (UMAG_02239),chromosome 5,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,A general reduction of disease in infection with mutant lacking see1.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22688,PHI:124580,UniProt,A0A0D1E5A8,GenBank,KIS70866,,,521,apb73 (UMAG_02011),chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,A general reduction of disease in infection with mutant lacking apb73.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22689,PHI:124581,UniProt,A0A0D1DX64,GenBank,KIS68804,,,521,sta1 (UMAG_02011),chromosome 8,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,A general reduction of disease in infection with mutant lacking sta1.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22690,PHI:124582,UniProt,A0A0D1DUQ9,GenBank,KIS67999,,,521,UMAG_11062,chromosome 11,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_11062 only showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22691,PHI:124583,UniProt,A0A0D1CF25,GenBank,KIS71612,,,521,UMAG_00054,chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_00054 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22692,PHI:124584,UniProt,A0A0D1CZH2,GenBank,KIS71663,,,521,UMAG_00104,chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_00104 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22693,PHI:124585,UniProt,A0A0D1CJB9,GenBank,KIS66998,,,521,UMAG_05780,chromosome 16,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_05780 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22694,PHI:124586,UniProt,A0A0D1DQD7,GenBank,KIS66196,,,521,UMAG_05932,chromosome 20,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_05932 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22695,PHI:124587,UniProt,A0A0D1CW02,GenBank,KIS70538,,,521,UMAG_11362,chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_11362 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22696,PHI:124588,UniProt,A0A0D1BVD8,GenBank,KIS66012,,,521,UMAG_11205,chromosome 21,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_11205 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22697,PHI:124589,UniProt,A0A0D1DYI3,GenBank,KIS68706,,,521,rsp3 (UMAG_03274),chromosome 8,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,A general reduction of disease in infection with mutant lacking rsp3 .,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22698,PHI:124590,UniProt,A0A0D1E8C1,GenBank,KIS71721,,,521,UMAG_00159,chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_00159 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22699,PHI:124591,UniProt,A0A0D1D169,GenBank,KIS72118,,,521,UMAG_00538,chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_00538 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22700,PHI:124592,UniProt,A0A0D1CHF8,GenBank,KIS72392,,,521,UMAG_00795,chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_00795 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22701,PHI:124593,UniProt,A0A0D1E6Y4,GenBank,KIS71341,,,521,UMAG_01241,chromosome 2,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_01241 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22702,PHI:124594,UniProt,A0A0D1E4Q7,GenBank,KIS70656,,,521,UMAG_01820,chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_01820 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22703,PHI:124595,UniProt,A0A0D1CWP9,GenBank,KIS70828,,,521,UMAG_01976,chromosome 3,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_01976 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22704,PHI:124596,UniProt,A0A0D1E1G8,GenBank,KIS69771,,,521,UMAG_02293,chromosome 5,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_02293 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22705,PHI:124597,UniProt,A0A0D1E1H1,GenBank,KIS69776,,,521,UMAG_02298,chromosome 5,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_02298 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22706,PHI:124598,UniProt,A0A0D1E1D4,GenBank,KIS69954,,,521,UMAG_02466,chromosome 5,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_02466 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22707,PHI:124599,UniProt,A0A0D1E2J4,GenBank,KIS68835,,,521,UMAG_02826,chromosome 7,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_02826 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22708,PHI:124600,UniProt,A0A0D1E1Y8,GenBank,KIS68565,,,521,UMAG_03138,chromosome 8,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_03138 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22709,PHI:124601,UniProt,A0A0D1E0J1,GenBank,KIS68240,,,521,UMAG_03822,chromosome 10,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_03822 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22710,PHI:124602,UniProt,A0A0D1DV84,GenBank,KIS67641,,,521,UMAG_04145,chromosome 12,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_04145 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22711,PHI:124603,UniProt,A0A0D1DYX1,GenBank,KIS67750,,,521,UMAG_04248,chromosome 12,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_04248 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22712,PHI:124604,UniProt,A0A0D1E6W5,GenBank,KIS70150,,,521,UMAG_05222,chromosome 4,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_05222 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22713,PHI:124605,UniProt,A0A0D1E2W3,GenBank,KIS70156,,,521,UMAG_05227,chromosome 4,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_05227 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22714,PHI:124606,UniProt,A0A0D1DRV1,GenBank,KIS66616,,,521,UMAG_05604,chromosome 18,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_05604 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22715,PHI:124607,UniProt,A0A0D1DRM3,GenBank,KIS66999,,,521,UMAG_05781,chromosome 16,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_05781 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22716,PHI:124608,UniProt,A0A0D1DPX0,GenBank,KIS66021,,,521,UMAG_06112,chromosome 21,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_06112 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22717,PHI:124609,UniProt,A0A0D1CFN1,GenBank,KIS65843,,,521,UMAG_06221,chromosome 22,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_06221 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22718,PHI:124610,UniProt,A0A0D1DTB8,GenBank,KIS65845,,,521,UMAG_06223,chromosome 22,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_06223 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22719,PHI:124611,UniProt,A0A0D1DMZ9,GenBank,KIS65879,,,521,UMAG_06255,chromosome 22,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_06255 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22720,PHI:124612,UniProt,A0A0D1E701,GenBank,KIS71689,,,521,UMAG_10030,chromosome 1,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_10030 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22721,PHI:124613,UniProt,A0A0D1E2M4,GenBank,KIS70081,,,521,UMAG_10186,chromosome 4,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_10186 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22722,PHI:124614,UniProt,A0A0D1E997,GenBank,KIS70960,,,521,UMAG_11839,chromosome 2,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_11839 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22723,PHI:124615,UniProt,A0A0D1CXX9,GenBank,KIS71223,,,521,UMAG_12127,chromosome 2,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_12127 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22724,PHI:124616,UniProt,A0A0D1DWR4,GenBank,KIS66960,,,521,UMAG_12313,chromosome 16,,,,,,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,Mutant lacking UMAG_12313 showed a reduction of the most severe disease categories.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22725,PHI:124617,UniProt,Q4PDL7,GenBank,KIS70631,,,521,UMAG_01796,chromosome 3,,,,,PHI:124618; PHI:124619; PHI:124620; PHI:124621; PHI:124622; PHI:124623; PHI:124624; PHI:124625,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff1 mutant lacking nine of eff1 family genes showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22726,PHI:124618,UniProt,A0A0D1E3Z8,GenBank,KIS70824,,,521,UMAG_11377,chromosome 3,,,,,PHI:124617; PHI:124619; PHI:124620; PHI:124621; PHI:124622; PHI:124623; PHI:124624; PHI:124625,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff1 mutant lacking nine of eff1 family genes showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22727,PHI:124619,UniProt,Q4PCM6,GenBank,KIS69602,,,521,UMAG_02137,chromosome 5,,,,,PHI:124617; PHI:124618; PHI:124620; PHI:124621; PHI:124622; PHI:124623; PHI:124624; PHI:124625,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff1 mutant lacking nine of eff1 family genes showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22728,PHI:124620,UniProt,Q4PCM5,GenBank,KIS69603,,,521,UMAG_02138,chromosome 5,,,,,PHI:124617; PHI:124618; PHI:124619; PHI:124621; PHI:124622; PHI:124623; PHI:124624; PHI:124625,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff1 mutant lacking nine of eff1 family genes showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22729,PHI:124621,UniProt,Q4PCM4,GenBank,KIS69604,,,521,UMAG_02139,chromosome 5,,,,,PHI:124617; PHI:124618; PHI:124619; PHI:124620; PHI:124622; PHI:124623; PHI:124624; PHI:124625,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff1 mutant lacking nine of eff1 family genes showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22730,PHI:124622,UniProt,E3CTN3,GenBank,KIS69605,,,521,UMAG_02140,chromosome 5,,,,,PHI:124617; PHI:124618; PHI:124619; PHI:124620; PHI:124621; PHI:124623; PHI:124624; PHI:124625,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff1 mutant lacking nine of eff1 family genes showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22731,PHI:124623,UniProt,Q4P9A0,GenBank,KIS68746,,,521,UMAG_03313,chromosome 8,,,,,PHI:124617; PHI:124618; PHI:124619; PHI:124620; PHI:124621; PHI:124622; PHI:124624; PHI:124625,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff1 mutant lacking nine of eff1 family genes showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22732,PHI:124624,UniProt,Q4P999,GenBank,KIS68747,,,521,UMAG_03314,chromosome 8,,,,,PHI:124617; PHI:124618; PHI:124619; PHI:124620; PHI:124621; PHI:124622; PHI:124623; PHI:124625,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff1 mutant lacking nine of eff1 family genes showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22733,PHI:124625,UniProt,Q4PCM2,GenBank,KIS69606,,,521,UMAG_02141,chromosome 5,,,,,PHI:124617; PHI:124618; PHI:124619; PHI:124620; PHI:124621; PHI:124622; PHI:124623; PHI:124624,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff1 mutant lacking nine of eff1 family genes showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22734,PHI:124626,UniProt,A0A0D1CRF7,GenBank,KIS69183,,,521,UMAG_11415,chromosome 6,,,,,PHI:124627; PHI:124628; PHI:124629; PHI:124630,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff2 mutant lacking five of eff2 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22735,PHI:124627,UniProt,A0A0D1DYP1,GenBank,KIS69184,,,521,UMAG_02535,chromosome 6,,,,,PHI:124626; PHI:124628; PHI:124629; PHI:124630,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff2 mutant lacking five of eff2 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22736,PHI:124628,UniProt,A0A0D1E3X3,GenBank,KIS69185,,,521,UMAG_11416,chromosome 6,,,,,PHI:124626; PHI:124627; PHI:124629; PHI:124630,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff2 mutant lacking five of eff2 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22737,PHI:124629,UniProt,A0A0D1DZX5,GenBank,KIS69186,,,521,UMAG_02537,chromosome 6,,,,,PHI:124626; PHI:124627; PHI:124628; PHI:124630,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff2 mutant lacking five of eff2 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22738,PHI:124630,UniProt,A0A0D1C6C3,GenBank,KIS69187,,,521,UMAG_02538,chromosome 6,,,,,PHI:124626; PHI:124627; PHI:124628; PHI:124629,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff2 mutant lacking five of eff2 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22739,PHI:124631,UniProt,A0A0D1E1A9,GenBank,KIS69701,,,521,UMAG_02229,chromosome 5,,,,,PHI:124632,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff3 mutant lacking two of eff3 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22740,PHI:124632,UniProt,P0CT27,GenBank,KIS69700,,,521,UMAG_10076,chromosome 5,,,,,PHI:124631,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff3 mutant lacking two of eff3 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22741,PHI:124633,UniProt,A0A0D1C393,GenBank,KIS68172,,,521,UMAG_03752,chromosome 10,,,,,PHI:124634,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff4 mutant lacking two of eff4 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22742,PHI:124634,UniProt,A0A0D1CND6,GenBank,KIS68173,,,521,UMAG_03753,chromosome 10,,,,,PHI:124633,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff4 mutant lacking two of eff4 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22743,PHI:124635,UniProt,A0A0D1CYK5,GenBank,KIS71398,,,521,UMAG_01297,chromosome 2,,,,,PHI:124636,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff5 mutant lacking two of eff5 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22744,PHI:124636,UniProt,A0A0D1E5X9,GenBank,KIS71399,,,521,UMAG_01298,chromosome 2,,,,,PHI:124635,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff5 mutant lacking two of eff5 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22745,PHI:124637,UniProt,A0A0D1E4Y8,GenBank,KIS71044,,,521,UMAG_00961,chromosome 2,,,,,PHI:124638,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff6 mutant lacking two of eff6 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22746,PHI:124638,UniProt,A0A0D1DZA9,GenBank,KIS68936,,,521,UMAG_02921,chromosome 7,,,,,PHI:124637,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff6 mutant lacking two of eff6 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22747,PHI:124639,UniProt,A0A0D1E951,GenBank,KIS72389,,,521,UMAG_00792,chromosome 1,,,,,PHI:124640,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff7 mutant lacking two of eff7 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22748,PHI:124640,UniProt,A0A0D1EDY9,GenBank,KIS72390,,,521,UMAG_00793,chromosome 1,,,,,PHI:124639,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff7 mutant lacking two of eff7 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22749,PHI:124641,UniProt,A0A0D1DUC4,GenBank,KIS66190,,,521,UMAG_05926,chromosome 20,,,,,PHI:124642,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff8 mutant lacking two of eff8 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22750,PHI:124642,UniProt,A0A0D1BVZ6,GenBank,KIS66192,,,521,UMAG_05928,chromosome 20,,,,,PHI:124641,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff8 mutant lacking two of eff8 family genes showed same virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22751,PHI:124643,UniProt,A0A0D1DT47,GenBank,KIS65735,,,521,UMAG_06440,chromosome 23,,,,,PHI:124644,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff9 mutant lacks both UMAG_06440 and UMAG_12316 and showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22752,PHI:124644,UniProt,A0A0D1DU27,GenBank,KIS66070,,,521,UMAG_12316,chromosome 20,,,,,PHI:124643,5270,Ustilago maydis,,SG200,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38416124,PubMed,10.1094/MPMI-09-23-0139-FI,Mol Plant Microbe Interact. 2024 Feb 28.,mariana.schuster@ipb-halle.de,The eff9 mutant lacks both UMAG_06440 and UMAG_12316 and showed small but significant reduction in all virulence symptoms compared to SG200.,M Schuster 2024,2024,72 genes,Schuster et al 2024,BATCH_131,2024-03-01,MC,,,,,,,,,,,,,
,,Record 22753,PHI:124645,UniProt,A0A194VAV4,GenBank,KUI60926,,,SXYL134,xlnR,chromosome unknown,,,VP1G_09520; VP1G_03128; VP1G_02856; VP1G_06369; VP1G_03782,UniProt: A0A194VEG9; GenBank: KUI62397; UniProt: A0A194UVT7; GenBank: KUI55805; UniProt: A0A,,694573,Valsa pyri,,Vp297,Valsa canker,eudicots,23211,Pyrus communis (related: pear),,,,Leaves; Branches,transcription factor,,,signaling pathway,reduced virulence,,,,,smaller lesions,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,35308334,PubMed,10.3389/fmicb.2022.784686,Front Microbiol. 2022 Mar 3;13:784686.,zhaoyc27@126.com,Lesion sizes produced by the vpxlnR mutants were significantly smaller than those produced by the wild-type and complementary strains at 2–5dpi.,F He 2022,2022,1 gene,He-2022-The Transcription Factor VpxlnR Is Req,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22754,PHI:124646,UniProt,I1RFV7,GenBank,CEF74924,,,PH-1,GmtA (FGSG_02598),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1 (NRRL 31084),Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,Wheat head; coleoptiles; corn silks,GDP-mannose transporter,,,,unaffected pathogenicity,,,yes,,wild type,wild type,increased,reduced,wild type,no,sodium dodecyl sulphate (SDS);fludioxonil;iprodione;Congo red;calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;fludioxonil: CHEBI:81763; ;iprodione: CHEBI:28909; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38535216,PubMed,10.3390/jof10030208,J Fungi (Basel). 2024 Mar 11;10(3):208.,zhangguifen@caas.cn,"The wild-type strain PH-1, ΔFgGmtA, and the complemented strains ΔFgGmtA-C were able to infect almost the entire wheat head.",C Zhao 2024,2024,2 genes,Zhao-2024-FgGmtB Plays an Important Role in Gr,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22755,PHI:124647,UniProt,I1RG50,GenBank,CEF75038,,,PH-1,GmtB (FGSG_02699),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1 (NRRL 31084),Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,Wheat head; coleoptiles; corn silks,GDP-mannose transporter,,,,loss of pathogenicity,,,yes,,no symptoms,increased,reduced,reduced,increased,no,sodium dodecyl sulphate (SDS);fludioxonil;iprodione;Congo red;calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;fludioxonil: CHEBI:81763; ;iprodione: CHEBI:28909; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38535216,PubMed,10.3390/jof10030208,J Fungi (Basel). 2024 Mar 11;10(3):208.,zhangguifen@caas.cn,ΔFgGmtB showed no symptoms and failed to infect the inoculation site.,C Zhao 2024,2024,2 genes,Zhao-2024-FgGmtB Plays an Important Role in Gr,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22756,PHI:124646,UniProt,I1RFV7,GenBank,CEF74924,,,PH-1,GmtA (FGSG_02598),chromosome 1,,,,,PHI:124647,5518,Fusarium graminearum,229533,PH-1 (NRRL 31084),Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,Wheat head; coleoptiles; corn silks,GDP-mannose transporter,,,,loss of pathogenicity,,,yes,,no symptoms,wild type,reduced,reduced,wild type,no,sodium dodecyl sulphate (SDS);fludioxonil;iprodione;Congo red;calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;fludioxonil: CHEBI:81763; ;iprodione: CHEBI:28909; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,38535216,PubMed,10.3390/jof10030208,J Fungi (Basel). 2024 Mar 11;10(3):208.,zhangguifen@caas.cn,ΔFgGmtA&B showed no symptoms and failed to infect the inoculation site.,C Zhao 2024,2024,2 genes,Zhao-2024-FgGmtB Plays an Important Role in Gr,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22757,PHI:124647,UniProt,I1RG50,GenBank,CEF75038,,,PH-1,GmtB (FGSG_02699),chromosome 1,,,,,PHI:124646,5518,Fusarium graminearum,229533,PH-1 (NRRL 31084),Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,Wheat head; coleoptiles; corn silks,GDP-mannose transporter,,,,loss of pathogenicity,,,yes,,no symptoms,wild type,reduced,reduced,wild type,no,sodium dodecyl sulphate (SDS);fludioxonil;iprodione;Congo red;calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;fludioxonil: CHEBI:81763; ;iprodione: CHEBI:28909; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,38535216,PubMed,10.3390/jof10030208,J Fungi (Basel). 2024 Mar 11;10(3):208.,zhangguifen@caas.cn,ΔFgGmtA&B showed no symptoms and failed to infect the inoculation site.,C Zhao 2024,2024,2 genes,Zhao-2024-FgGmtB Plays an Important Role in Gr,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22758,PHI:124648,UniProt,G4MTK9,GenBank,EHA55568,,,70-15,Ypd1p (MGG_07173),chromosome 2,,,,,,318829,Magnaporthe oryzae,,70-15,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,phosphotransfer protein,,,HOG signaling pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,sorbitol;KCl;fludioxonil,sorbitol: CHEBI:30911; ;KCl: CHEBI:32588; ;fludioxonil: CHEBI:81763,,,,,gene deletion: full ; gene complementation,,,NN,38438487,PubMed,10.1038/s42003-024-05941-z,Commun Biol. 2024 Mar 4;7(1):265.,jacob@ibwf.de,"The wildtype strain 70-15 was found to cause significant lesions on detached rice leaves, whereas the mutant strains have been documented to be less virulent.",S Bühring 2024,2024,1 gene,B?hring-2024-An array of signal-specific MoYpd,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22759,PHI:124649,UniProt,A0A7U7JE37,GenBank,CEJ17230,,,IPO1609,RipAB,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,leaves,effector protein,,,,effector (plant avirulence determinant),,,,,high disease severity,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,35043960,PubMed,10.1093/plcell/koac015,Plant Cell. 2022 Apr 26;34(5):1666-1683.,boli@mail.hzau.edu.cn,RipAB overexpression strain displayed more severe and faster disease symptoms compared with WT plants.,P Qi 2022,2022,1 gene,Qi-2022-A Ralstonia solanacearum effector targ,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22760,PHI:124649,UniProt,A0A7U7JE37,GenBank,CEJ17230,,,IPO1609,RipAB,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Money Maker,,,leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35043960,PubMed,10.1093/plcell/koac015,Plant Cell. 2022 Apr 26;34(5):1666-1683.,boli@mail.hzau.edu.cn,The Δripab strains caused a very weak wilting phenotype or even completely lost pathogenicity.,P Qi 2022,2022,1 gene,Qi-2022-A Ralstonia solanacearum effector targ,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22761,PHI:124649,UniProt,A0A7U7JE37,GenBank,CEJ17230,,,IPO1609,RipAB,,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35043960,PubMed,10.1093/plcell/koac015,Plant Cell. 2022 Apr 26;34(5):1666-1683.,boli@mail.hzau.edu.cn,The Δripab strains caused a very weak wilting phenotype or even completely lost pathogenicity.,P Qi 2022,2022,1 gene,Qi-2022-A Ralstonia solanacearum effector targ,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22762,PHI:124650,UniProt,A0A220QM05,GenBank,OR394961,,,,CFEM1,,,,,,,474922,Colletotrichum gloeosporioides,,SAMN17266943,fruit rot,eudicots,3981,Hevea brasiliensis (related: rubber tree),73-3-97,,,Light green leaves,common fungal extracellular membrane (CFEM) domain protein,,,signalling pathway,reduced virulence,,,,,smaller necrotic lesions,reduced,,wild type,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38474183,PubMed,10.3390/ijms25052937,Int J Mol Sci. 2024 Mar 2;25(5):2937.,wangqiannan@hainanu.edu.cn,The size of the necrotic induced by ΔCgCFEM1 were significantly smaller than those induced by WT and Complementary strain.,L Feng 2024,2024,1 gene,Feng-2024-CgCFEM1 Is Required for the Full Vir,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22763,PHI:124651,UniProt,A7E621,GenBank,EDN91343,,,1980,GH5 (Ss1G_00746),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980 (ATCC 18683),white mould,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,leaves,glycosyl hydrolase 5,,,,reduced virulence,,,,,some lesion,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38473940,PubMed,10.3390/ijms25052693,Int J Mol Sci. 2024 Feb 26;25(5):2693.,jiasencheng@mail.hzau.edu.cn,Knocking out SsGH5 did not affect the growth but resulted in decreased glucan utilization and significantly reduced virulence.,X Liu 2024,2024,1 gene,Liu-2024-A Glycosyl Hydrolase 5 Family Protein,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22764,PHI:124651,UniProt,A7E621,GenBank,EDN91343,,,1980,GH5 (Ss1G_00746),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980 (ATCC 18683),white mould,eudicots,3708,Brassica napus (related: rape),Westar,,,leaves,glycosyl hydrolase 5,,,,reduced virulence,,,,,some lesion,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38473940,PubMed,10.3390/ijms25052693,Int J Mol Sci. 2024 Feb 26;25(5):2693.,jiasencheng@mail.hzau.edu.cn,Knocking out SsGH5 did not affect the growth but resulted in decreased glucan utilization and significantly reduced virulence.,X Liu 2024,2024,1 gene,Liu-2024-A Glycosyl Hydrolase 5 Family Protein,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22765,PHI:124652,UniProt,G4N7X0,GenBank,EHA50924,,,70-15,Ste11,chromosome 4,,,CcSte50,,,,Cytospora chrysosperma,,Cytospora chrysosperma,canker disease,eudicots,1217306,Populus x beijingensis (related: poplar),,,,Twigs,STE like transcription factor,,,MAPKs pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38225467,PubMed,10.1007/s44154-023-00142-w,Stress Biol. 2024 Jan 16;4(1):4.,xiongdianguang@126.com,"Deletion of CcSte11 resulted in slowed growth, loss of sporulation and virulence, similar to the defects observed in the CcPmk1 deletion mutant.",L Yu 2024,2024,2 genes,Yu-2024-The mitogen-activated protein kinase m,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22766,PHI:124653,UniProt,G4NEB8,GenBank,EHA48601,,,70-15,Ste7,chromosome 4,,,CcSte50,,,,Cytospora chrysosperma,,Cytospora chrysosperma,canker disease,eudicots,1217306,Populus x beijingensis (related: poplar),,,,Twigs,STE like transcription factor,,,MAPKs pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38225467,PubMed,10.1007/s44154-023-00142-w,Stress Biol. 2024 Jan 16;4(1):4.,xiongdianguang@126.com,"Deletion of CcSte7 resulted in slowed growth, loss of sporulation and virulence, similar to the defects observed in the CcPmk1 deletion mutant.",L Yu 2024,2024,2 genes,Yu-2024-The mitogen-activated protein kinase m,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22767,PHI:124654,UniProt,G4ZWX2,GenBank,EGZ11743,,,P6497,CZF1 (EU912575.1),chromosome unknown,,,,,,100870,Peronophythora litchii,,SHS3,litchi downy blight,eudicots,151069,Litchi chinensis (related: Tender litchi),Feizixiao,,,leaves,C2H2 zinc finger protein,,,,reduced virulence,,,,,smaller lesions,wild type,increased,wild type,,no,,,,,,,gene deletion: full,,,NN,35269874,PubMed,10.3390/ijms23052733,Int J Mol Sci. 2022 Mar 1;23(5):2733.,xpg@scau.edu.cn,"Compared with the wild type, the Δplczf1 mutants showed no significant difference in vegetative growth and asexual reproduction, but were defective in oospore development and virulence.",H Zhu 2022,2022,1 gene,Zhu-2022-A C(2)H(2) Zinc Finger Protein PlCZF1,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22768,PHI:124655,UniProt,G4MQL4,GenBank,EHA56504,,,70-15,NIS1,chromosome 1,,,,,,474922,Colletotrichum gloeosporioides,,CSLL11,fruit rot,eudicots,4072,Capsicum annuum (no common name found),,,,leaves,secreted protein 1,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,38542475,PubMed,10.3390/ijms25063505,Int J Mol Sci. 2024 Mar 20;25(6):3505.,hnsfcy@126.com,"The results showed that there was a large water-soaking lesion on the leaves of the peppers 3 days after inoculation with the mycelium of wild-type and complemented strains, while the lesion area in the ΔCgnis1 mutant strain was significantly reduced.",S Guo 2024,2024,1 gene,Guo-2024-CgNis1's Impact on Virulence and Stre,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22769,PHI:124655,UniProt,G4MQL4,GenBank,EHA56504,,,70-15,NIS1,chromosome 1,,,,,,474922,Colletotrichum gloeosporioides,,CSLL11,fruit rot,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaves,secreted protein 1,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,38542475,PubMed,10.3390/ijms25063505,Int J Mol Sci. 2024 Mar 20;25(6):3505.,hnsfcy@126.com,"The results showed that there was a large water-soaking lesion on the leaves of the tobacco 3 days after inoculation with the mycelium of wild-type and complemented strains, while the lesion area in the ΔCgnis1 mutant strain was significantly reduced.",S Guo 2024,2024,1 gene,Guo-2024-CgNis1's Impact on Virulence and Stre,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22770,PHI:124656,UniProt,G2XHN6,GenBank,EGY19330,,,VdLs.17,MRTF1 (VDAG_09790),chromosome 3,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Seedlings,transcription factor,,,,increased virulence (hypervirulence),,,,,high disease severity,,,increased,,no,CaCl2,CaCl2: CHEBI:3312,,,,,gene deletion: full ; gene complementation,,,NN,35404080,PubMed,10.1128/spectrum.02581-21,Microbiol Spectr. 2022 Apr 27;10(2):e0258121.,ylwang@bjfu.edu.cn,The disease index of tobacco seedlings inoculated with the ΔVdMRTF1 strain was higher than that observed following inoculation with the wildt type and ΔVdMRTF1-C strain.,M Lai 2022,2022,1 gene,Lai et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22771,PHI:124657,UniProt,G4MSY9,GenBank,EHA54648,,,70-15,MTA1 (MGG_01492),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4530,Oryza sativa (related: rice),,,,leaves,methyltransferase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,35338654,PubMed,10.1111/nph.18117,New Phytol. 2022 Jul;235(1):247-262.,chenxiaolin@mail.hzau.edu.cn,The Δmta1 mutant showed reduced virulence due to blockage of appressorial penetration and invasive growth.,Z Ren 2022,2022,2 genes,Ren et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22772,PHI:124657,UniProt,G4MSY9,GenBank,EHA54648,,,70-15,MTA1 (MGG_01492),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4513,Hordeum vulgare (related: barley),,,,leaves,methyltransferase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,35338654,PubMed,10.1111/nph.18117,New Phytol. 2022 Jul;235(1):247-262.,chenxiaolin@mail.hzau.edu.cn,The Δmta1 mutant showed reduced virulence due to blockage of appressorial penetration and invasive growth.,Z Ren 2022,2022,2 genes,Ren et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22773,PHI:124658,UniProt,Q51MW4,GenBank,EHA48293,,,70-15,ATG8,chromosome 5,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4530,Oryza sativa (related: rice),,,,leaves,autophagy-related protein,,,,loss of pathogenicity,,,,,no lesion,reduced,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35338654,PubMed,10.1111/nph.18117,New Phytol. 2022 Jul;235(1):247-262.,chenxiaolin@mail.hzau.edu.cn,The pathogenicity of strain Δatg8 was completely lost.,Z Ren 2022,2022,2 genes,Ren et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22774,PHI:124658,UniProt,Q51MW4,GenBank,EHA48293,,,70-15,ATG8,chromosome 5,ATG8A982C,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4530,Oryza sativa (related: rice),,,,leaves,autophagy-related protein,,,,loss of pathogenicity,,,,,smaller necrotic lesions,reduced,,wild type,,no,,,,,,,gene mutation,,,NN,35338654,PubMed,10.1111/nph.18117,New Phytol. 2022 Jul;235(1):247-262.,chenxiaolin@mail.hzau.edu.cn,"Mutant strain Δatg8/ATG8A982C can cause disease, the number and area of necrotic lesions were significantly reduced, and the pathogenicity was seriously reduced.",Z Ren 2022,2022,2 genes,Ren et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22775,PHI:124658,UniProt,Q51MW4,GenBank,EHA48293,,,70-15,ATG8,chromosome 5,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4513,Hordeum vulgare (related: barley),,,,leaves,autophagy-related protein,,,,loss of pathogenicity,,,,,no lesion,reduced,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35338654,PubMed,10.1111/nph.18117,New Phytol. 2022 Jul;235(1):247-262.,chenxiaolin@mail.hzau.edu.cn,The pathogenicity of strain Δatg8 was completely lost.,Z Ren 2022,2022,2 genes,Ren et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22776,PHI:124658,UniProt,Q51MW4,GenBank,EHA48293,,,70-15,ATG8,chromosome 5,ATG8A982C,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4513,Hordeum vulgare (related: barley),,,,leaves,autophagy-related protein,,,,loss of pathogenicity,,,,,smaller necrotic lesions,reduced,,wild type,,no,,,,,,,gene mutation,,,NN,35338654,PubMed,10.1111/nph.18117,New Phytol. 2022 Jul;235(1):247-262.,chenxiaolin@mail.hzau.edu.cn,"Mutant strain Δatg8/ATG8A982C can cause disease, the number and area of necrotic lesions were significantly reduced, and the pathogenicity was seriously reduced.",Z Ren 2022,2022,2 genes,Ren et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22777,PHI:124659,UniProt,G5AAQ7,GenBank,EGZ07686,,,P6497,ATG2,chromosome unknown,,,,,,100870,Peronophythora litchii,,SHS3,litchi downy blight,eudicots,151069,Litchi chinensis (related: Tender litchi),,,,Leaves: Fruits,autophagy-related protein,,,autophagy pathway,loss of pathogenicity,,,,,no lesion,reduced,reduced,reduced,,no,sorbitol;hydrogen peroxide (H2O2);KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,38438325,PubMed,10.1080/21505594.2024.2322183,Virulence. 2024 Dec;15(1):2322183.,qhchen@hainanu.edu.cn,Infection assays demonstrated that ΔPlatg2 mutants showed significantly impaired pathogenicity in litchi leaves and fruits.,L Lv 2024,2024,1 gene,Lv et al 2024,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22778,PHI:124660,UniProt,W7M0G1,GenBank,EWG40994,,,7600,Med18 (FVEG_03198),chromosome 5,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,reduced,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22779,PHI:124661,UniProt,W7LM77,GenBank,EWG40498,,,7600,Med1 (FVEG-02872),chromosome 5,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,reduced,,wild type,wild type,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22780,PHI:124662,UniProt,W7LUZ7,GenBank,EWG43053,,,7600,Med9 (FVEG_04688),chromosome 4,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,increased,,wild type,wild type,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22781,PHI:124663,UniProt,W7M3F9,GenBank,EWG39397,,,7600,Med31 (FVEG_02237),chromosome 6,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,reduced,,wild type,wild type,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22782,PHI:124664,UniProt,W7MIS6,GenBank,EWG47529,,,7600,Med3 (FVEG_07603),chromosome 8,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,reduced,,wild type,wild type,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22783,PHI:124665,UniProt,W7M8I4,GenBank,EWG47868,,,7600,Med5 (FVEG_07865),chromosome 3,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,increased,,wild type,wild type,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22784,PHI:124666,UniProt,W7LY57,GenBank,EWG37492,,,7600,Med16 (FVEG_01083),chromosome 1,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,reduced,,wild type,wild type,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22785,PHI:124667,UniProt,W7LKH5,GenBank,EWG39001,,,7600,Med12 (FVEG_02030),chromosome 6,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,reduced,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22786,PHI:124668,UniProt,W7LIC3,GenBank,EWG39123,,,7600,Med13 (FVEG_02107),chromosome 6,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,reduced,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22787,PHI:124669,UniProt,W7MXN2,GenBank,EWG52599,,,7600,Fcc1 (FVEG_11306),chromosome 9,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,reduced,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22788,PHI:124670,UniProt,W7MX65,GenBank,EWG52394,,,7600,Fck1 (FVEG_11159),chromosome 9,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Kernels,mediator subunit,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,reduced,no,NaCl;Congo red,NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,35271780,PubMed,10.1094/PHYTO-12-21-0495-R,Phytopathology. 2022 Aug;112(8):1730-1738.,wbshim@tamu.edu,All mutants exhibited less severe seedling rot symptoms than wild type,Z Zhou 2022,2022,11 genes,Zhou et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22789,PHI:124671,UniProt,A0A8E5HTX7,GenBank,QUC21164,,,UV-8b,Gap1 (Uv8b_05407),chromosome 4,,,UvRas2 (Uv8b_07519); UvRasGef (Uv8b_00435),UniProt: A0A8E5HXB9; GenBank: QUC23278; UniProt: A0A8E5HIU8; GenBank: QUC16194,,1159556,Ustilaginoidea virens,,P-1,rice false smut disease,monocots,4530,Oryza sativa (related: rice),Liangyoupeijiu,,,Spikelets,Ras GTPase-activating protein,,,Ras pathway,loss of pathogenicity,,,yes,,no smut balls,wild type,,reduced,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38502297,PubMed,10.1111/mpp.13448,Mol Plant Pathol. 2024 Mar;25(3):e13448.,liuyf@jaas.ac.cn,No false smut balls were observed in spikelets inoculated with the ΔUvgap1 mutant.,H Cao 2024,2024,3 genes,Cao et al 2024,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22790,PHI:124672,UniProt,A0A8E5HXI9,GenBank,QUC23307,,,UV-8b,Gap2 (Uv8b_075480),chromosome 6,,,UvRas2 (Uv8b_07519); UvRasGef (Uv8b_00435),UniProt: A0A8E5HXB9; GenBank: QUC23278; UniProt: A0A8E5HIU8; GenBank: QUC16194,,1159556,Ustilaginoidea virens,,P-1,rice false smut disease,monocots,4530,Oryza sativa (related: rice),Liangyoupeijiu,,,Spikelets,Ras GTPase-activating protein,,,Ras pathway,unaffected pathogenicity,,,yes,,false smut balls,wild type,,reduced,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38502297,PubMed,10.1111/mpp.13448,Mol Plant Pathol. 2024 Mar;25(3):e13448.,liuyf@jaas.ac.cn,"At 30 dpi, spikelets of rice inoculated with P-1, mutants (ΔUvgap2 and ΔUvgap3), and complementation strain Uvgap1-c showed the presence of approximately 15–25 false smut balls.",H Cao 2024,2024,3 genes,Cao et al 2024,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22791,PHI:124673,UniProt,A0A8E5HSY0,GenBank,QUC20790,,,UV-8b,Gap3 (Uv8b_05031),chromosome 4,,,UvRas2 (Uv8b_07519); UvRasGef (Uv8b_00435),UniProt: A0A8E5HXB9; GenBank: QUC23278; UniProt: A0A8E5HIU8; GenBank: QUC16194,,1159556,Ustilaginoidea virens,,P-1,rice false smut disease,monocots,4530,Oryza sativa (related: rice),Liangyoupeijiu,,,Spikelets,Ras GTPase-activating protein,,,Ras pathway,unaffected pathogenicity,,,yes,,false smut balls,wild type,,wild type,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,38502297,PubMed,10.1111/mpp.13448,Mol Plant Pathol. 2024 Mar;25(3):e13448.,liuyf@jaas.ac.cn,"At 30 dpi, spikelets of rice inoculated with P-1, mutants (ΔUvgap2 and ΔUvgap3), and complementation strain Uvgap1-c showed the presence of approximately 15–25 false smut balls.",H Cao 2024,2024,3 genes,Cao et al 2024,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22792,PHI:124674,UniProt,A0A1Y6JIV3,GenBank,SMS09887,,,CFBP 1590,mexB,chromosome I,,,,,,317,Pseudomonas syringae,205918,B728a,brown spot on bean,eudicots,3885,Phaseolus vulgaris (related: string bean),Blue Lake Bush 274,,,Leaves,efflux transporter,,,,reduced virulence,,,,,fewer lesion,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35343250,PubMed,10.1094/MPMI-04-21-0099-R,Mol Plant Microbe Interact. 2022 Aug;35(8):672-680.,icelab@berkeley.edu,"B728a ΔmexB formed fewer lesions per leaf than the WT; WT strain resulted in a median of 15 and a mean of 28.8 lesions/leaf, whereas inoculation with the mexB mutant resulted in a me dian of 2 and a mean of 5.7 lesions/leaf.",T C Helmann 2022,2022,1 gene,Helmann et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22793,PHI:124674,UniProt,A0A1Y6JIV3,GenBank,SMS09887,,,CFBP 1590,mexB,chromosome I,,,,,,317,Pseudomonas syringae,205918,B728a,brown spot on bean,eudicots,3885,Phaseolus lunatus (related: lima bean),,,,Leaves,efflux transporter,,,,reduced virulence,,,,,fewer lesion,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35343250,PubMed,10.1094/MPMI-04-21-0099-R,Mol Plant Microbe Interact. 2022 Aug;35(8):672-680.,icelab@berkeley.edu,"B728a ΔmexB formed fewer lesions per leaf than the WT; WT strain resulted in a median of 15 and a mean of 28.8 lesions/leaf, whereas inoculation with the mexB mutant resulted in a median of 2 and a mean of 5.7 lesions/leaf.",T C Helmann 2022,2022,1 gene,Helmann et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22794,PHI:124674,UniProt,A0A1Y6JIV3,GenBank,SMS09887,,,CFBP 1590,mexB,chromosome I,,,,,,317,Pseudomonas syringae,205918,B728a,brown spot on bean,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,efflux transporter,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35343250,PubMed,10.1094/MPMI-04-21-0099-R,Mol Plant Microbe Interact. 2022 Aug;35(8):672-680.,icelab@berkeley.edu,B728a ΔmexB formed wild type lesions per leaf than the WT.,T C Helmann 2022,2022,1 gene,Helmann et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22795,PHI:124675,UniProt,X0JK55,GenBank,EXM01674,,,54006,ECM33,chromosome unknown,,,,,,5507,Fusarium oxysporum,1229665,f.sp. Cubense Focub TR4 strain II5 (NRRL#54006),Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),AAA,,,Roots,GPI-anchored protein,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,Congo red;calcofluor white (CFW),Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,35183338,PubMed,10.1016/j.funbio.2021.12.005,Fungal Biol. 2022 Mar;126(3):213-223.,lichunyu@gdaas.cn,"The targeted disruption of FocECM33 led to decreased hyphal growth, increased sensitivity to cell wall stresses and reduced virulence on banana plantlets.",H Huang 2022,2022,1 gene,Huang et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22796,PHI:124676,UniProt,A0A0S4TY37,GenBank,CUV14964,,,Phyl III-seqv23,NorA,chromosome I,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Bonny Best,,,Seedlings,NO-binding protein,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,35377234,PubMed,10.1128/spectrum.00264-22,Microbiol Spectr. 2022 Apr 27;10(2):e0026422.,callen@wisc.edu,The ΔnorA mutant caused significantly same bacterial wilt symptoms as wild type.,A N Truchon 2022,2022,2 genes,Truchon et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22797,PHI:124677,UniProt,A0A0S4UKD5,GenBank,CUV21018,,,Phyl III-seqv23,NorB,chromosome III,,,,,,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Bonny Best,,,Seedlings,nitric oxide reductase,,,,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35377234,PubMed,10.1128/spectrum.00264-22,Microbiol Spectr. 2022 Apr 27;10(2):e0026422.,callen@wisc.edu,The ΔnorB mutant caused significantly reduced bacterial wilt symptoms than wild type.,A N Truchon 2022,2022,2 genes,Truchon et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22798,PHI:124676,UniProt,A0A0S4TY37,GenBank,CUV14964,,,Phyl III-seqv23,NorA,chromosome I,,,,,PHI:124677,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Bonny Best,,,Seedlings,NO-binding protein,,,,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35377234,PubMed,10.1128/spectrum.00264-22,Microbiol Spectr. 2022 Apr 27;10(2):e0026422.,callen@wisc.edu,The ΔnorB/norA double mutant caused significantly reduced bacterial wilt symptoms than wild type.,A N Truchon 2022,2022,2 genes,Truchon et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22799,PHI:124677,UniProt,A0A0S4UKD5,GenBank,CUV21018,,,Phyl III-seqv23,NorB,chromosome III,,,,,PHI:124676,305,Ralstonia solanacearum,267608,GMI1000,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Bonny Best,,,Seedlings,nitric oxide reductase,,,,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full,,,NN,35377234,PubMed,10.1128/spectrum.00264-22,Microbiol Spectr. 2022 Apr 27;10(2):e0026422.,callen@wisc.edu,The ΔnorB/norA double mutant caused significantly reduced bacterial wilt symptoms than wild type.,A N Truchon 2022,2022,2 genes,Truchon et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22800,PHI:124678,UniProt,G2XFX7,GenBank,EGY18796,,,VdLs.17,HP1 (VDAG_08956),chromosome 5,,,,,,27337,Verticillium dahliae,,Vd080,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Jimian11,,,Seedlings; stem,hydrophobic protein,,,,increased virulence (hypervirulence),,,yes,,high disease severity,,reduced,increased,,no,sorbitol;NaCl;KCl;Congo red,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,35377232,PubMed,10.1128/spectrum.02478-21,Microbiol Spectr. 2022 Apr 27;10(2):e0247821.,weifeng@caas.cn,"Disease index (DI) of cotton plants infected by ΔVdHP1-1 and ΔVdHP1-2 strains were about 74.16 and 75.31, while that of cotton plants infected by WT, C-ΔVdHP1-1 and C-ΔVdHP1-2 were only about 51.00, 54.55, and 52.67.",X Zhang 2022,2022,1 gene,X Zhang et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22801,PHI:124679,UniProt,A0A0J9WWV3,GenBank,ACD59124,,,PXO99A,PXO_01041,,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocots,4530,Oryza sativa (related: rice),Nipponbare,,,leaves,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35184695,PubMed,10.1080/15592324.2022.2035126,Plant Signal Behav. 2022 Dec 31;17(1):2035126.,Jhongtaoji@jsnu.edu.cn,ΔxopZ (PXO_01041 and PXO_06125) mutant strains displayed lower virulence on Nipponbare leaves compared with PXO99 strains.,H Ji 2022,2022,2 genes,ji et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22802,PHI:124680,UniProt,A0A0J9WWV3,GenBank,ACD59124,,,PXO99A,PXO_06125,,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocots,4530,Oryza sativa (related: rice),Nipponbare,,,leaves,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,35184695,PubMed,10.1080/15592324.2022.2035126,Plant Signal Behav. 2022 Dec 31;17(1):2035126.,Jhongtaoji@jsnu.edu.cn,ΔxopZ (PXO_01041 and PXO_06125) mutant strains displayed lower virulence on Nipponbare leaves compared with PXO99 strains.,H Ji 2022,2022,2 genes,ji et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22803,PHI:124681,UniProt,G2XHA9,GenBank,EGY19207,,,VdLs.17,Chr2g00380 (VDAG_09541 ),chromosome 7,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Money Maker,,,Seedlings,cytochrome P450 monooxygenase,,,,reduced virulence,,,yes,,low disease severity,reduced,,wild type,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,35224980,PubMed,10.1094/PHYTO-08-21-0318-R,Phytopathology. 2022 Aug;112(8):1723-1729.,ylwang@bifu.edu.cn,The virulence assays showed that deletion of Chr2G00380 in JR2 resulted in attenuated virulence on tomato and tobacco plants.,J Zhang 2022,2022,1 gene,Zhang et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22804,PHI:124681,UniProt,G2XHA9,GenBank,EGY19207,,,VdLs.17,Chr2g00380 (VDAG_09541 ),chromosome 7,,,,,,27337,Verticillium dahliae,1202531,JR2,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Seedlings,cytochrome P450 monooxygenase,,,,reduced virulence,,,yes,,low disease severity,reduced,,wild type,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,35224980,PubMed,10.1094/PHYTO-08-21-0318-R,Phytopathology. 2022 Aug;112(8):1723-1729.,ylwang@bifu.edu.cn,The virulence assays showed that deletion of Chr2G00380 in JR2 resulted in attenuated virulence on tomato and tobacco plants.,J Zhang 2022,2022,1 gene,Zhang et al 2022,BATCH_132,2024-04-01,MC,,,,,,,,,,,,,
,,Record 22805,PHI:124682,UniProt,G4MQR2,GenBank,EHA57349,,,70-15,Erv29,chromosome 1,,,MoSlp1,UniProt: A0A1P8W6L1; GenBank: APZ88176,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,COPII cargo receptor,,,UPR pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,"Deletion of MoERV29 severely affected the vegetative growth, conidiation and biotrophic invasion of the fungus in susceptible rice hosts.",B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22806,PHI:124682,UniProt,G4MQR2,GenBank,EHA57349,,,70-15,Erv29,chromosome 1,,,MoSlp1,UniProt: A0A1P8W6L1; GenBank: APZ88176,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),,,,Leaves,COPII cargo receptor,,,UPR pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,"Deletion of MoERV29 severely affected the vegetative growth, conidiation and biotrophic invasion of the fungus in susceptible barley hosts.",B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22807,PHI:124683,UniProt,A0A1P8W6L1,GenBank,APZ88176,,,,Slp1,,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,Deletion of MoSlp1 severely affected the severely affected the virulence on rice.,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22808,PHI:124683,UniProt,A0A1P8W6L1,GenBank,APZ88176,,,,Slp1,,glycine–proline–proline (APP) - isoleucine–proline–valine (IPV),,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,,,no,,,,,,,gene mutation,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,we found that the MoSLP1IPV construct could complement the virulence of Moslp1 mutant more efficiently than MoSLP1EET.,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22809,PHI:124683,UniProt,A0A1P8W6L1,GenBank,APZ88176,,,,Slp1,,glycine–proline–proline (APP) - Glutamic acid–glutamic acid–threonine (EET),,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,,,no,,,,,,,gene mutation,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,we found that the MoSLP1IPV construct could complement the virulence of Moslp1 mutant more efficiently than MoSLP1EET.,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22810,PHI:124684,UniProt,G4NDC4,GenBank,EHA49262,,,70-15,Ecp1 (MGG_00259),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,Moecp1 mutant was significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22811,PHI:124685,UniProt,G4NDK9,GenBank,EHA49294,,,70-15,MGG_00227,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,MGG_00227 mutant did not significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22812,PHI:124686,UniProt,G4MUE7,GenBank,EHA54834,,,70-15,MGG_01655,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,MGG_01655 mutant did not significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22813,PHI:124687,UniProt,G4N0V4,GenBank,EHA52332,,,70-15,MGG_05790,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,MGG_05790 mutant did not significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22814,PHI:124688,UniProt,G4MYQ1,GenBank,EHA55280,,,70-15,MGG_08127,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,MGG_08127 mutant did not significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22815,PHI:124689,UniProt,G4MZ98,GenBank,EHA55371,,,70-15,MGG_08200,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,MGG_08200 mutant did not significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22816,PHI:124690,UniProt,Q2KEU2,GenBank,EAQ71537,,,70-15,MGG_09139,chromosome 7,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,MGG_09139 mutant did not significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22817,PHI:124691,UniProt,G4ND85,GenBank,EHA49223,,,70-15,MGG_11608,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,MGG_11608 mutant did not significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22818,PHI:124692,UniProt,G4N3F5,GenBank,EHA51833,,,70-15,MGG_13464,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,MGG_13464 mutant did not significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22819,PHI:124684,UniProt,G4NDC4,GenBank,EHA49262,,,70-15,Ecp1 (MGG_00259),chromosome 5,glycine–proline–proline (APP) - isoleucine–proline–valine (IPV),,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,increased virulence (hypervirulence),,,,,large lesions,,,,,no,,,,,,,gene mutation,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,Moecp1IPV mutant was significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22820,PHI:124684,UniProt,G4NDC4,GenBank,EHA49262,,,70-15,Ecp1 (MGG_00259),chromosome 5,glycine–proline–proline (APP) - Glutamic acid–glutamic acid–threonine (EET),,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,cargo proteins,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene mutation,,,NN,34761375,PubMed,10.1111/nph.17851,New Phytol. 2022 Feb;233(3):1289-1302.,zhgzhang@njau.edu.cn,Moecp1IPV mutant was significantly attenuated in virulence,B Qian 2022,2022,11 genes,Qian-2022-MoErv29 promotes apoplastic effector,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22821,PHI:124693,UniProt,A0A5N5D8C9,GenBank,KAB2573897,,,LA-SOL3,Ap1,,,,,,,45133,Lasiodiplodia theobromae,,JMB122,grapevine canker disease,eudicots,3760,Prunus persica (related: peach),,,,Shoots,bZip transcription factor,,,,reduced virulence,,,,,smaller necrotic lesions,,,,,no,,,,,,,gene mutation,,,NN,34630367,PubMed,10.3389/fmicb.2021.741842,Front Microbiol. 2021 Sep 23;12:741842.,junwei.liu@mail.hzau.edu.cn,LtAP1-deletion mutant had slower vegetative growth and decreased virulence.,H Zhang 2021,2021,1 gene,Zhang-2021-The bZIP Transcription Factor LtAP1,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22822,PHI:124694,UniProt,A0A4U9FGY6,GenBank,CAG1965400,,,MDC_Fg202,Pfn (FGSG_06392),,,,FgMyo5; FgAct,UniProt: A0A2H3HCB8; GenBank: CAG1991896,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Huaimai 33,,,Spikelets; Coleoptiles,profilins,,,,reduced virulence,,,,,mild disease,reduced,reduced,reduced,wild type,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38701108,PubMed,10.1371/journal.ppat.1012215,PLoS Pathog. 2024 May 3;20(5):e1012215.,houyiping@njau.edu.cn,"ΔFgPfn could only lead to a mild disease at the inoculation site of the wheat heads and coleoptiles, which could not spread further compared with PH-1 and ΔFgPfn-C.",Z Yuan 2024,2024,1 gene,Yuan-2024-FgPfn participates in vegetative gro,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22823,PHI:124694,UniProt,A0A4U9FGY6,GenBank,CAG1965400,,,MDC_Fg202,Pfn (FGSG_06392),,FgPfnF62H,,FgMyo5; FgAct,UniProt: A0A2H3HCB8; GenBank: CAG1991896,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Huaimai 33,,,Coleoptiles,profilins,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,wild type,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene mutation,,,NN,38701108,PubMed,10.1371/journal.ppat.1012215,PLoS Pathog. 2024 May 3;20(5):e1012215.,houyiping@njau.edu.cn,Mutation FgPfnF62H was similar to the wild type and complementary of ΔFgPfn,Z Yuan 2024,2024,1 gene,Yuan-2024-FgPfn participates in vegetative gro,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22824,PHI:124694,UniProt,A0A4U9FGY6,GenBank,CAG1965400,,,MDC_Fg202,Pfn (FGSG_06392),,FgPfnR86K; FgPfnI101E; FgPfnD124E,,FgMyo5,UniProt: A0A2H3HCB8; GenBank: CAG1991896,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Huaimai 33,,,Coleoptiles,profilins,,,,reduced virulence,,,,,mild disease,reduced,,reduced,wild type,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene mutation,,,NN,38701108,PubMed,10.1371/journal.ppat.1012215,PLoS Pathog. 2024 May 3;20(5):e1012215.,houyiping@njau.edu.cn,"Mutantion FgPfnR86K, FgPfnI101E and FgPfnD124E was similar to that observed in the FgPfn deletion mutant.",Z Yuan 2024,2024,1 gene,Yuan-2024-FgPfn participates in vegetative gro,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22825,PHI:124695,UniProt,A0A2K9QB41,GenBank,AUQ24191,,,MS2,OhrR,,,,,,,204042,Dickeya zeae,1427366,EC1,soft rot diseases,eudicots,4113,Solanum tuberosum (related: potato),Bintje,,,tuber,organic hydroperoxide reductase regulator,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34693617,PubMed,10.1111/mpp.13141,Mol Plant Pathol. 2022 Jan;23(1):45-59.,lhzhang01@scau.edu.cn,The results showed that the deletion of ohrR significantly reduced the maceration zones by about 67% and 83% compared to the wild-type strain EC1 and the complemented strain.,M Lv 2022,2022,1 gene,Lv-2022-OhrR is a central transcriptional regu,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22826,PHI:124695,UniProt,A0A2K9QB41,GenBank,AUQ24191,,,MS2,OhrR,,,,,,,204042,Dickeya zeae,1427366,EC1,soft rot diseases,eudicots,3726,Raphanus sativus (related: radish),Bintje,,,tuber,organic hydroperoxide reductase regulator,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34693617,PubMed,10.1111/mpp.13141,Mol Plant Pathol. 2022 Jan;23(1):45-59.,lhzhang01@scau.edu.cn,The results showed that the deletion of ohrR significantly reduced the maceration zones by about 67% and 83% compared to the wild-type strain EC1 and the complemented strain.,M Lv 2022,2022,1 gene,Lv-2022-OhrR is a central transcriptional regu,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22827,PHI:124695,UniProt,A0A2K9QB41,GenBank,AUQ24191,,,MS2,OhrR,,,,,,,204042,Dickeya zeae,1427366,EC1,soft rot diseases,monocot,4530,Oryza sativa (related: rice),,,,Seedlings,organic hydroperoxide reductase regulator,,,,loss of pathogenicity,,,,,no symptom,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34693617,PubMed,10.1111/mpp.13141,Mol Plant Pathol. 2022 Jan;23(1):45-59.,lhzhang01@scau.edu.cn,The lengths of shoots and roots germinated from treated seeds were similar to that of the water-treated control.,M Lv 2022,2022,1 gene,Lv-2022-OhrR is a central transcriptional regu,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22828,PHI:124696,UniProt,G4N332,GenBank,EHA52588,,,70-15,Mad1 (MGG_04908),chromosome 3,,,MoMps1 (MGG_10826),UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,SAC protein,,,,reduced virulence,,,,,low disease severity,reduced,,wild type,reduced,no,nocodazole,nocodazole: CHEBI:34892,,,,,gene deletion: full ; gene complementation,,,NN,38619864,PubMed,10.1111/mpp.13456,Mol Plant Pathol. 2024 Apr;25(4):e13456.,wangmo108@163.com,"ΔMomad1 mutants displayed significantly decreased in fection area, indicating that deletion of MoMad1 compromised M.oryzae pathogenicity.",Q Chen 2024,2024,2 genes,Chen-2024-Phosphorylation of Mad1 at serine 18,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22829,PHI:124696,UniProt,G4N332,GenBank,EHA52588,,,70-15,Mad1 (MGG_04908),chromosome 3,MoMad1S18A,,MoMps1 (MGG_10826),UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,SAC protein,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene mutation,,,NN,38619864,PubMed,10.1111/mpp.13456,Mol Plant Pathol. 2024 Apr;25(4):e13456.,wangmo108@163.com,"MoMad1S18D, but not MoMad1S18A, could recover the decreased pathogenicity of ΔMomad1-41 to the similar level of level of ΔMomad1-41/MoMAD1.",Q Chen 2024,2024,2 genes,Chen-2024-Phosphorylation of Mad1 at serine 18,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22830,PHI:124696,UniProt,G4N332,GenBank,EHA52588,,,70-15,Mad1 (MGG_04908),chromosome 3,MoMad1S18D,,MoMps1 (MGG_10826),UniProt: G4MYX1; GenBank: EHA53632,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,SAC protein,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene mutation,,,NN,38619864,PubMed,10.1111/mpp.13456,Mol Plant Pathol. 2024 Apr;25(4):e13456.,wangmo108@163.com,"MoMad1S18D, but not MoMad1S18A, could recover the decreased pathogenicity of ΔMomad1-41 to the similar level of level of ΔMomad1-41/MoMAD1.",Q Chen 2024,2024,2 genes,Chen-2024-Phosphorylation of Mad1 at serine 18,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22831,PHI:124697,UniProt,G4MYX1,GenBank,EHA53632,,,70-15,Mps1 (MGG_10826),chromosome 2,D695 mutated to A,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,TTK protein kinase,,,,reduced virulence,,,,,low disease severity,reduced,,wild type,reduced,no,,,,,,,gene mutation,,,NN,38619864,PubMed,10.1111/mpp.13456,Mol Plant Pathol. 2024 Apr;25(4):e13456.,wangmo108@163.com,"When Mps1-IN-1 was added into the Guy11 conidial suspension, the disease incidence was significantly decreased.",Q Chen 2024,2024,2 genes,Chen-2024-Phosphorylation of Mad1 at serine 18,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22832,PHI:124697,UniProt,G4MYX1,GenBank,EHA53632,,,70-15,Mps1 (MGG_10826),chromosome 2,D695 mutated to A,,,,PHI:124696,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,TTK protein kinase,,,,reduced virulence,,,,,low disease severity,reduced,,wild type,reduced,no,,,,,,,gene mutation,,,NN,38619864,PubMed,10.1111/mpp.13456,Mol Plant Pathol. 2024 Apr;25(4):e13456.,wangmo108@163.com,"When Mps1-IN-1/MoMad1S18A was double mutated, the disease incidence was significantly decreased.",Q Chen 2024,2024,2 genes,Chen-2024-Phosphorylation of Mad1 at serine 18,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22833,PHI:124696,UniProt,G4N332,GenBank,EHA52588,,,70-15,Mad1 (MGG_04908),chromosome 3,MoMad1S18A,,MoMps1 (MGG_10826),UniProt: G4MYX1; GenBank: EHA53632,PHI:124697,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,SAC protein,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene mutation,,,NN,38619864,PubMed,10.1111/mpp.13456,Mol Plant Pathol. 2024 Apr;25(4):e13456.,wangmo108@163.com,"When Mps1-IN-1/MoMad1S18A was double mutated, the disease incidence was significantly decreased.",Q Chen 2024,2024,2 genes,Chen-2024-Phosphorylation of Mad1 at serine 18,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22834,PHI:124697,UniProt,G4MYX1,GenBank,EHA53632,,,70-15,Mps1 (MGG_10826),chromosome 2,D695 mutated to A,,,,PHI:124696,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,TTK protein kinase,,,,unaffected pathogenicity,,,,,wild type,reduced,,wild type,reduced,no,,,,,,,gene mutation,,,NN,38619864,PubMed,10.1111/mpp.13456,Mol Plant Pathol. 2024 Apr;25(4):e13456.,wangmo108@163.com,"When Mps1-IN-1/MoMad1S18D was double mutated, the disease incidence was significantly same as wild type.",Q Chen 2024,2024,2 genes,Chen-2024-Phosphorylation of Mad1 at serine 18,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22835,PHI:124696,UniProt,G4N332,GenBank,EHA52588,,,70-15,Mad1 (MGG_04908),chromosome 3,MoMad1S18D,,MoMps1 (MGG_10826),UniProt: G4MYX1; GenBank: EHA53632,PHI:124697,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,SAC protein,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene mutation,,,NN,38619864,PubMed,10.1111/mpp.13456,Mol Plant Pathol. 2024 Apr;25(4):e13456.,wangmo108@163.com,"When Mps1-IN-1/MoMad1S18D was double mutated, the disease incidence was significantly same as wild type.",Q Chen 2024,2024,2 genes,Chen-2024-Phosphorylation of Mad1 at serine 18,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22836,PHI:124698,UniProt,A0A140CZL3,GenBank,AMJ52176,,,EV-MIL31,Sho1,,,,AaSte50; AaSte11; AaPbs2; AaHog1,UniProt: A0A177DUF3; GenBank: OAG23128; UniProt: A0A177DZL6; GenBank: OAG25175; UniProt: I3V,,5599,Alternaria alternata,,JT-03,brown spot disease,eudicots,23211,Pyrus communis (related: pear),,,,fruit,high-osmolarity-sensitive protein,,,HOG-MAPK signaling pathwa,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38680872,PubMed,10.1016/j.csbj.2024.04.031,Comput Struct Biotechnol J. 2024 Apr 12;23:1594-1607.,lyc@gsau.edu.cn,"Compared to the wild-type (WT), the ΔAaSho1 mutant strain showed no significant difference in colony growth, morphology, conidial production and showed reduced virulence.",Y Liu 2024,2024,1 gene,Liu-2024-The sensor protein AaSho1 regulates i,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22837,PHI:124699,UniProt,T0L2X0,GenBank,EQB58834,,,Cg-14,Rac1,,,,,,,1209932,Colletotrichum scovillei,,KC05,anthracnose,eudicots,4072,Capsicum annuum (no common name found),,,,fruit,small GTPase,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,34897252,PubMed,10.5423/PPJ.OA.09.2021.0140,Plant Pathol J. 2021 Dec;37(6):607-618.,kims@kangwon.ac.kr,"ΔCsrac1 showed pleiotropic defects in fungal growth and developments, including vegetative growth, conidiogenesis, conidial germination and virulence.",N H Lee 2021,2021,1 gene,Lee-2021-The Small GTPase CsRAC1 Is Important,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22838,PHI:124700,UniProt,A7E8C2,GenBank,EDN96624,,,1980,Dim5 (SS1G_01550),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,3708,Brassica napus (related: rape),ZS11,,,leaves,histone methyltransferase,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);potassium cyanide (KCN),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;potassium cyanide (KCN): CHEBI:33191,,,,,gene deletion: full ; gene complementation,,,NN,38667942,PubMed,10.3390/jof10040271,J Fungi (Basel). 2024 Apr 6;10(4):271.,xstone0505@hunau.edu.cn,"After 24 h of infection, the lesion areas caused by the knock out strains Ssdim5-1/Ssdim5-2 were significantly smaller than that induced by the WT, whereas the lesion area caused by the complementation strain SsDim5-C resembled that of the WT.",L Qin 2024,2024,1 gene,Qin-2024-Histone Methyltransferase SsDim5 Regu,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22839,PHI:124700,UniProt,A7E8C2,GenBank,EDN96624,,,1980,Dim5 (SS1G_01550),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaves,histone methyltransferase,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);potassium cyanide (KCN),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;potassium cyanide (KCN): CHEBI:33191,,,,,gene deletion: full ; gene complementation,,,NN,38667942,PubMed,10.3390/jof10040271,J Fungi (Basel). 2024 Apr 6;10(4):271.,xstone0505@hunau.edu.cn,"After 24 h of infection, the lesion areas caused by the knock out strains Ssdim5-1/Ssdim5-2 were significantly smaller than that induced by the WT, whereas the lesion area caused by the complementation strain SsDim5-C resembled that of the WT.",L Qin 2024,2024,1 gene,Qin-2024-Histone Methyltransferase SsDim5 Regu,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22840,PHI:124701,UniProt,A0A2H3GP66,GenBank,CAG1983013,,,MDC_Fg202,Fad12 (FGSG_05784),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Annong8455,,,wheat heads; Coleoptiles; Corn silk,fatty acid desaturase domain-containing protein,,,desaturation pathway,reduced virulence,,,,,low disease severity,wild type,wild type,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38667959,PubMed,10.3390/jof10040288,J Fungi (Basel). 2024 Apr 14;10(4):288.,xynuym@163.com,"Deletion of the FgFAD12 gene resulted in defects in vegetative growth, conidial germination and plant pathogenesis but not sexual reproduction.",Y Zhang 2024,2024,1 gene,Zhang-2024-FgFAD12 Regulates Vegetative Growth,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22841,PHI:124702,UniProt,G2X8V1,GenBank,EGY15388,,,VdLs.17,Sti1 (VDAG_06242),chromosome 8,,,VdExt2 (VDAG_10388),UniProt: G2XJQ6; GenBank: EGY20759,,27337,Verticillium dahliae,,Vd080,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Jimian 11,,,Seedlings; stem,stress-induced co-chaperone protein,,,ergosterol synthesis pathway,reduced virulence,,,,,low disease severity,wild type,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38638896,PubMed,10.3389/fmicb.2024.1377713,Front Microbiol. 2024 Apr 4;15:1377713.,fzlsky@126.com,"The ΔVdSti1-1 and ΔVdSti1-2 mutant strains exhibited significantly reduced yellow wilt symptoms, leading to a substantial decrease in the disease index by approximately 0.35 and 0.38 times.",Y Wu 2024,2024,1 gene,Wu-2024-The role of VdSti1 in Verticillium dah,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22842,PHI:124703,UniProt,A0A0B5L7L9,GenBank,AJG44813,,,,Pep 1 (KP256757),,,,,,,49012,Sporisorium scitamineum,1447027; no data found,JG36; JG35,sugarcane smut,monocots,4547,Saccharum officinarum (related: sugarcane),ROC22,,,Plantlets,effector protein,,,MAPK signaling pathway,effector (plant avirulence determinant),,,,,low disease severity,,,wild type,,,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,34829241,PubMed,10.3390/jof7110954,J Fungi (Basel). 2021 Nov 11;7(11):954.,chenyaoj@gxu.edu.cn,"With inoculation of the wild-type strains JG35 × JG36, 91.7% of the plantlets produced whips whereas the mutant showed reduced whips in plantlets.",S Lu 2021,2021,1 gene,"Lu-2021-SsPEP1, an Effector with Essential Cel",BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22843,PHI:124704,UniProt,A0A977TNI4,GenBank,UXX33815,,,,GPA1 (MZ574567),,,,,,,984309,Ciboria shiraiana,,WCCQ01,hypertrophy sorosis scleroteniosis,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,G protein α subunit gene,,,cAMP/PKA and MAPK pathway,reduced virulence,,,,,smaller necrotic lesions,reduced,,wild type,,no,hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: silencing,,,NN,34947035,PubMed,10.3390/jof7121053,J Fungi (Basel). 2021 Dec 8;7(12):1053.,tzhu@cqu.edu.cn,There were significantly less necrotic lesions for CsGPA1-silenced strains than WT and EV strains,P Zhu 2021,2021,2 genes,Zhu-2021-Host-Induced Gene Silencing of a G Pr,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22844,PHI:124705,UniProt,A0A977TNH4,GenBank,UXX33816,,,,GPA2 (MZ574568),,,,,,,984309,Ciboria shiraiana,,WCCQ01,hypertrophy sorosis scleroteniosis,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,G protein α subunit gene,,,cAMP/PKA and MAPK pathway,reduced virulence,,,,,smaller necrotic lesions,reduced,,wild type,,no,hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: silencing,,,NN,34947035,PubMed,10.3390/jof7121053,J Fungi (Basel). 2021 Dec 8;7(12):1053.,tzhu@cqu.edu.cn,The CsGPA2 RNAi strains showed a slight non-significant reduction in virulence.,P Zhu 2021,2021,2 genes,Zhu-2021-Host-Induced Gene Silencing of a G Pr,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22845,PHI:124706,UniProt,N4VVN8,GenBank,TDZ19150,,,104-T,SIB1 (TDZ19150.1),,,,,,,5465,Colletotrichum orbiculare,1213857,104-T (MAFF240422),anthracnose of Cucurbitaceae,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,34756891,PubMed,10.1016/j.jbc.2021.101370,J Biol Chem. 2021 Dec;297(6):101370.,takano.yoshitaka.2x@kyoto-u.ac.jp,CE7 (SIB1) caused lesion development before C. orbiculare inoculation.,R Zhang 2021,2021,2 genes,Zhang-2021-Fungal effector SIB1 of Colletotric,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22846,PHI:124707,UniProt,N4V2U6,GenBank,TDZ19243,,,104-T,SIB2 (TDZ19243.1),,,,,,,5465,Colletotrichum orbiculare,1213857,104-T (MAFF240422),anthracnose of Cucurbitaceae,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,34756891,PubMed,10.1016/j.jbc.2021.101370,J Biol Chem. 2021 Dec;297(6):101370.,takano.yoshitaka.2x@kyoto-u.ac.jp,CE5 (SIB2) caused lesion development before C. orbiculare inoculation.,R Zhang 2021,2021,2 genes,Zhang-2021-Fungal effector SIB1 of Colletotric,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22847,PHI:124706,UniProt,N4VVN8,GenBank,TDZ19150,,,104-T,SIB1 (TDZ19150.1),,,,,,,5465,Colletotrichum orbiculare,1213857,104-T (MAFF240422),anthracnose of Cucurbitaceae,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,34756891,PubMed,10.1016/j.jbc.2021.101370,J Biol Chem. 2021 Dec;297(6):101370.,takano.yoshitaka.2x@kyoto-u.ac.jp,"sib1Δ strains on N. benthamiana, cucumber, and melon and found that the sib1Δ strains developed the same lesions as the control strain for all plants tested.",R Zhang 2021,2021,2 genes,Zhang-2021-Fungal effector SIB1 of Colletotric,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22848,PHI:124706,UniProt,N4VVN8,GenBank,TDZ19150,,,104-T,SIB1 (TDZ19150.1),,,,,,,5465,Colletotrichum orbiculare,1213857,104-T (MAFF240422),anthracnose of Cucurbitaceae,eudicots,3656,Cucumis melo (related: muskmelon),,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,34756891,PubMed,10.1016/j.jbc.2021.101370,J Biol Chem. 2021 Dec;297(6):101370.,takano.yoshitaka.2x@kyoto-u.ac.jp,"sib1Δ strains on N. benthamiana, cucumber, and melon and found that the sib1Δ strains developed the same lesions as the control strain for all plants tested.",R Zhang 2021,2021,2 genes,Zhang-2021-Fungal effector SIB1 of Colletotric,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22849,PHI:124706,UniProt,N4VVN8,GenBank,TDZ19150,,,104-T,SIB1 (TDZ19150.1),,,,,,,5465,Colletotrichum orbiculare,1213857,104-T (MAFF240422),anthracnose of Cucurbitaceae,eudicots,3659,Cucumis sativus (related: cucumber),,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,34756891,PubMed,10.1016/j.jbc.2021.101370,J Biol Chem. 2021 Dec;297(6):101370.,takano.yoshitaka.2x@kyoto-u.ac.jp,"sib1Δ strains on N. benthamiana, cucumber, and melon and found that the sib1Δ strains developed the same lesions as the control strain for all plants tested.",R Zhang 2021,2021,2 genes,Zhang-2021-Fungal effector SIB1 of Colletotric,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22850,PHI:124708,UniProt,G5EH22,GenBank,EAQ71125,,,70-15,Pal1 (MGG_02779),chromosome 7,,,Sla1,UniProt: G4MNJ5; GenBank: EHA57901,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,endocytic protein,,,cAMP and Pmk1 signalling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,34636149,PubMed,10.1111/mpp.13149,Mol Plant Pathol. 2022 Jan;23(1):133-147.,chenxiaolin@mail.hzau.edu.cn,Deletion of PAL1 significantly reduced the virulence of M. oryzae due to defects in appressorial penetration and invasive growth in host cells.,D Chen 2022,2022,1 gene,Chen-2022-Endocytic protein Pal1 regulates app,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22851,PHI:124708,UniProt,G5EH22,GenBank,EAQ71125,,,70-15,Pal1 (MGG_02779),chromosome 7,,,Sla1,UniProt: G4MNJ5; GenBank: EHA57901,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4513,Hordeum vulgare (related: barley),E9,,,leaves,endocytic protein,,,cAMP and Pmk1 signalling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,34636149,PubMed,10.1111/mpp.13149,Mol Plant Pathol. 2022 Jan;23(1):133-147.,chenxiaolin@mail.hzau.edu.cn,Deletion of PAL1 significantly reduced the virulence of M. oryzae due to defects in appressorial penetration and invasive growth in host cells.,D Chen 2022,2022,1 gene,Chen-2022-Endocytic protein Pal1 regulates app,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22852,PHI:124709,UniProt,A7F7J7,GenBank,EDN98718,,,1980,pka2 (XP_001585338.1),,,,,,,5180,Sclerotinia sclerotiorum,,UF1,white mould,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,protein kinase A,,,cAMP-dependent protein kinase A pathway,unaffected pathogenicity,,,,,no symptom,reduced,,reduced,,no,,,,,,,gene disruption ; gene complementation,,,NN,34930556,PubMed,10.1016/j.funbio.2021.09.004,Fungal Biol. 2022 Jan;126(1):20-34.,plyu@ufl.edu,Sspka2 disruption mutant failed to cause symptoms on non- wounded Nicotiana benthamiana leaves but not in wounded leaves.,P L Yu 2022,2022,2 genes,Yu-2022-The cAMP-dependent protein kinase A,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22853,PHI:124710,UniProt,A7EYX0,GenBank,EDN94662,,,1980,pkaR (XM_001588040.1),,,,,,,5180,Sclerotinia sclerotiorum,,UF1,white mould,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,protein kinase A,,,cAMP-dependent protein kinase A pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene disruption ; gene complementation,,,NN,34930556,PubMed,10.1016/j.funbio.2021.09.004,Fungal Biol. 2022 Jan;126(1):20-34.,plyu@ufl.edu,"dSspkaR mutants were able to develop symptoms on N. benthamiana with or without wounding, and yet the virulence was greatly reduced.",P L Yu 2022,2022,2 genes,Yu-2022-The cAMP-dependent protein kinase A,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22854,PHI:124709,UniProt,A7F7J7,GenBank,EDN98718,,,1980,pka2 (XP_001585338.1),,,,,,,5180,Sclerotinia sclerotiorum,,UF1,white mould,eudicots,3906,Vicia faba (related: fava bean),Windsor,,,Leaves,protein kinase A,,,cAMP-dependent protein kinase A pathway,unaffected pathogenicity,,,,,no symptom,reduced,,reduced,,no,,,,,,,gene disruption ; gene complementation,,,NN,34930556,PubMed,10.1016/j.funbio.2021.09.004,Fungal Biol. 2022 Jan;126(1):20-34.,plyu@ufl.edu,Sspka2 disruption mutant failed to cause symptoms on non- wounded bean leaves but not in wounded leaves.,P L Yu 2022,2022,2 genes,Yu-2022-The cAMP-dependent protein kinase A,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22855,PHI:124710,UniProt,A7EYX0,GenBank,EDN94662,,,1980,pkaR (XM_001588040.1),,,,,,,5180,Sclerotinia sclerotiorum,,UF1,white mould,eudicots,3906,Vicia faba (related: fava bean),Windsor,,,Leaves,protein kinase A,,,cAMP-dependent protein kinase A pathway,unaffected pathogenicity,,,,,no symptom,reduced,,reduced,,no,,,,,,,gene disruption ; gene complementation,,,NN,34930556,PubMed,10.1016/j.funbio.2021.09.004,Fungal Biol. 2022 Jan;126(1):20-34.,plyu@ufl.edu,dSspkaR mutants failed to develop symptoms on bean non-wounded leaves but not in wounding leaves.,P L Yu 2022,2022,2 genes,Yu-2022-The cAMP-dependent protein kinase A,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22856,PHI:124709,UniProt,A7F7J7,GenBank,EDN98718,,,1980,pka2 (XP_001585338.1),,,,,,,5180,Sclerotinia sclerotiorum,,UF1,white mould,eudicots,3847,Glycine max (related: soybean),2330 RR,,,Leaves,protein kinase A,,,cAMP-dependent protein kinase A pathway,unaffected pathogenicity,,,,,no symptom,reduced,,reduced,,no,,,,,,,gene disruption ; gene complementation,,,NN,34930556,PubMed,10.1016/j.funbio.2021.09.004,Fungal Biol. 2022 Jan;126(1):20-34.,plyu@ufl.edu,Sspka2 disruption mutant failed to cause symptoms on non- wounded soybean leaves but not in wounded leaves.,P L Yu 2022,2022,2 genes,Yu-2022-The cAMP-dependent protein kinase A,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22857,PHI:124710,UniProt,A7EYX0,GenBank,EDN94662,,,1980,pkaR (XM_001588040.1),,,,,,,5180,Sclerotinia sclerotiorum,,UF1,white mould,eudicots,3847,Glycine max (related: soybean),2330 RR,,,Leaves,protein kinase A,,,cAMP-dependent protein kinase A pathway,unaffected pathogenicity,,,,,no symptom,reduced,,reduced,,no,,,,,,,gene disruption ; gene complementation,,,NN,34930556,PubMed,10.1016/j.funbio.2021.09.004,Fungal Biol. 2022 Jan;126(1):20-34.,plyu@ufl.edu,dSspkaR mutants failed to develop symptoms on soybean non-wounded leaves but not in wounding leaves.,P L Yu 2022,2022,2 genes,Yu-2022-The cAMP-dependent protein kinase A,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22858,PHI:124709,UniProt,A7F7J7,GenBank,EDN98718,,,1980,pka2 (XP_001585338.1),,,,,,,5180,Sclerotinia sclerotiorum,,UF1,white mould,eudicots,4081,Solanum lycopersicum (related: tomato),Better Boy,,,Leaves,protein kinase A,,,cAMP-dependent protein kinase A pathway,unaffected pathogenicity,,,,,no symptom,reduced,,reduced,,no,,,,,,,gene disruption ; gene complementation,,,NN,34930556,PubMed,10.1016/j.funbio.2021.09.004,Fungal Biol. 2022 Jan;126(1):20-34.,plyu@ufl.edu,Sspka2 disruption mutant failed to cause symptoms on non- wounded tomato leaves but not in wounded leaves.,P L Yu 2022,2022,2 genes,Yu-2022-The cAMP-dependent protein kinase A,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22859,PHI:124710,UniProt,A7EYX0,GenBank,EDN94662,,,1980,pkaR (XM_001588040.1),,,,,,,5180,Sclerotinia sclerotiorum,,UF1,white mould,eudicots,4081,Solanum lycopersicum (related: tomato),Better Boy,,,Leaves,protein kinase A,,,cAMP-dependent protein kinase A pathway,unaffected pathogenicity,,,,,no symptom,reduced,,reduced,,no,,,,,,,gene disruption ; gene complementation,,,NN,34930556,PubMed,10.1016/j.funbio.2021.09.004,Fungal Biol. 2022 Jan;126(1):20-34.,plyu@ufl.edu,dSspkaR mutants failed to develop symptoms on tomato non-wounded leaves but not in wounding leaves.,P L Yu 2022,2022,2 genes,Yu-2022-The cAMP-dependent protein kinase A,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22860,PHI:124711,UniProt,A0A140F3N5,GenBank,AML61199,,,68,MAT1-1 (AML61199),,,,,,,5503,Cochliobolus lunatus,,ZD958,Curvularia leaf spot of maize,monocot,4577,Zea mays (related: maize),Huangzaosi,,,Leaves,mating-type protein MAT-1,,,,reduced virulence,,,,,fewer lesions,wild type,,wild type,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,34738831,PubMed,10.1094/PHYTO-02-21-0063-R,Phytopathology. 2022 May;112(5):1055-1062.,syxiaoshuqin@163.com,"At 12 days postinoculation, although obvious lesions appeared on the leaves, the total lesion area was reduced in leaves infected with Clmat1-1 mutant compared with ZD958.",K X Liu 2022,2022,2 genes,Liu-2022-Mating Type Genes Control Sexual Rep,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22861,PHI:124712,UniProt,A0A140F3N6,GenBank,AML61200,,,CX-3,MAT1-2 (AML61200),,,,,,,5503,Cochliobolus lunatus,1263492,CX-3,Curvularia leaf spot of maize,monocot,4577,Zea mays (related: maize),Huangzaosi,,,Leaves,mating-type protein MAT-2,,,,reduced virulence,,,,,fewer lesions,wild type,,wild type,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,34738831,PubMed,10.1094/PHYTO-02-21-0063-R,Phytopathology. 2022 May;112(5):1055-1062.,syxiaoshuqin@163.com,"At 12 days postinoculation, although obvious lesions appeared on the leaves, the total lesion area was reduced in leaves infected with Clmat1-2 mutant compared with CX-3.",K X Liu 2022,2022,2 genes,Liu-2022-Mating Type Genes Control Sexual Rep,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22862,PHI:124713,UniProt,X0J5P9,GenBank,EXL96528,,,54006,GCN5 (EXL96528.1),chromosome unknown,,,,,,5507,Fusarium oxysporum,1089451,f. sp. Cubense; Foc TR4,Fusarium wilt,monocots,4641,Musa acuminata (related: dwarf banana),Brazilian,,,Pseudostem,histone acetyltransferase,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,34838989,PubMed,10.1016/j.resmic.2021.103902,Res Microbiol. 2022 Mar-Apr;173(3):103902.,wangqiannan@hainanu.edu.cn,The pathogenicity of FocGCN5 mutant was dramatically decreased in comparison with WT: WT treated plantlets with the 96.7% disease scores where 16.7% of disease score in FocGCN5 mutant.,J Liu 2022,2022,1 gene,Liu-2022-The histone acetyltransferase Foc,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22863,PHI:124714,UniProt,A0A7X5MXL1,GenBank,NEL77697,,,,tssM,,,,,,,442694,Xanthomonas perforans,,AL65,bacterial spot disease,eudicots,4081,Solanum lycopersicum (related: tomato),FL8000,,,,type VI secretion system,,,,increased virulence (hypervirulence),,,,,high disease severity,,,wild type,,no,,,,,,,gene mutation ; gene complementation,,,NN,34543058,PubMed,10.1094/PHYTO-02-21-0069-R,Phytopathology. 2022 Apr;112(4):752-764.,nzp0024@auburn.edu,"AL65ΔtssM mutant exhibited quicker disease symptom development as early as 3 dpi, whereas AL65 and complementary showed water-shoking lesions.",P Liyanapathiranage 2022,2022,1 gene,Liyanapathiranage-2022-Liyanapathiranage et al 2022,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22864,PHI:124714,UniProt,A0A7X5MXL1,GenBank,NEL77697,,,,tssM,,,,,,,442694,Xanthomonas perforans,,AL65,bacterial spot disease,eudicots,4081,Solanum lycopersicum (related: tomato),FL8000,,,,type VI secretion system,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34543058,PubMed,10.1094/PHYTO-02-21-0069-R,Phytopathology. 2022 Apr;112(4):752-764.,nzp0024@auburn.edu,No difference was observed in symptom development within wild type and AL65ΔtssM mutant.,P Liyanapathiranage 2022,2022,1 gene,Liyanapathiranage-2022-Liyanapathiranage et al 2022,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22865,PHI:124715,UniProt,A0A2H3GBM8,GenBank,CAG1995058,,,MDC_Fg202,Con7 (FGSG_04134),,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Eunpamil,,,Spikelets,regulator,,,,reduced virulence,,,,,less symptoms,reduced,reduced,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38591889,PubMed,10.1128/msphere.00818-23,mSphere. 2024 Apr 9:e0081823.,hogongi7@snu.ac.kr,"ΔFgcon7 mutants did not induce any blight symptoms, even in the inoculated spikelets, while the wild-type, FgCON7c, and FgCON7oe strains exhibited typical head blight symptoms 21 days post-inoculation.",S Shin 2024,2024,1 gene,Shin-2024-Con7 is a key transcription regu,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22866,PHI:124715,UniProt,A0A2H3GBM8,GenBank,CAG1995058,,,MDC_Fg202,Con7 (FGSG_04134),,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Eunpamil,,,Spikelets,regulator,,,,unaffected pathogenicity,,,,,wild type,increased,reduced,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,38591889,PubMed,10.1128/msphere.00818-23,mSphere. 2024 Apr 9:e0081823.,hogongi7@snu.ac.kr,"ΔFgcon7 mutants did not induce any blight symptoms, even in the inoculated spikelets, while the wild-type, FgCON7c, and FgCON7oe strains exhibited typical head blight symptoms 21 days post-inoculation.",S Shin 2024,2024,1 gene,Shin-2024-Con7 is a key transcription regu,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22867,PHI:124716,UniProt,G4N8D9,GenBank,EHA50987,,,70-15,HOX7 (MGG_12865),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11 Δku70,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,transcription factor,,,Pmk1-dependent phosphorylation pathway,loss of pathogenicity,,,,,no symptom,,,reduced ; aberrant,,no,,,,,,,gene deletion: full,,,NN,34707224,PubMed,10.1038/s41564-021-00978-w,Nat Microbiol. 2021 Nov;6(11):1383-1397.,miriam.oses-ruiz@tsl.ac.uk,"Guy11 and Δku70 were able to cause plant infection but, by contrast, the Δhox7 mutant was non-pathogenic.",M Osés-Ruiz 2021,2021,8 genes,Oses-Ruiz-2021-Appressorium-mediated plant infecti,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22868,PHI:124717,UniProt,G4MU26,GenBank,EHA55626,,,70-15,rpp3 (MGG_07218),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11 Δku70,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,transcription factor,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,34707224,PubMed,10.1038/s41564-021-00978-w,Nat Microbiol. 2021 Nov;6(11):1383-1397.,miriam.oses-ruiz@tsl.ac.uk,Δrpp3 mutant was reduced in virulence.,M Osés-Ruiz 2021,2021,8 genes,Oses-Ruiz-2021-Appressorium-mediated plant infecti,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22869,PHI:124717,UniProt,G4MU26,GenBank,EHA55626,,,70-15,rpp3 (MGG_07218),chromosome 2,,,,,PHI:124718,318829,Magnaporthe oryzae,,Guy11 Δku70,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,transcription factor,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,34707224,PubMed,10.1038/s41564-021-00978-w,Nat Microbiol. 2021 Nov;6(11):1383-1397.,miriam.oses-ruiz@tsl.ac.uk,Δrpp3Δpig1 mutant was reduced in virulence.,M Osés-Ruiz 2021,2021,8 genes,Oses-Ruiz-2021-Appressorium-mediated plant infecti,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22870,PHI:124718,UniProt,G4MU22,GenBank,EHA55622,,,70-15,pig1 (MGG_07215),chromosome 2,,,,,PHI:124717,318829,Magnaporthe oryzae,,Guy11 Δku70,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,transcription factor,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,34707224,PubMed,10.1038/s41564-021-00978-w,Nat Microbiol. 2021 Nov;6(11):1383-1397.,miriam.oses-ruiz@tsl.ac.uk,Δrpp3Δpig1 mutant was reduced in virulence.,M Osés-Ruiz 2021,2021,8 genes,Oses-Ruiz-2021-Appressorium-mediated plant infecti,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22871,PHI:124719,UniProt,G4MNS7,GenBank,EHA56293,,,70-15,alcR (MGG_02129),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11 Δku70,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,transcription factor,,,,increased virulence (hypervirulence),,,,,larger lesions,,,,,no,,,,,,,gene deletion: full,,,NN,34707224,PubMed,10.1038/s41564-021-00978-w,Nat Microbiol. 2021 Nov;6(11):1383-1397.,miriam.oses-ruiz@tsl.ac.uk,The ΔaclR mutant caused slightly more blast lesions than Guy11.,M Osés-Ruiz 2021,2021,8 genes,Oses-Ruiz-2021-Appressorium-mediated plant infecti,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22872,PHI:124720,UniProt,Q2KEQ5,GenBank,EAQ71574,,,70-15,rpp1 (MGG_10212),chromosome 7,,,,,,318829,Magnaporthe oryzae,,Δku70,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,transcription factor,,,,increased virulence (hypervirulence),,,,,larger lesions,,,,,no,,,,,,,gene deletion: full,,,NN,34707224,PubMed,10.1038/s41564-021-00978-w,Nat Microbiol. 2021 Nov;6(11):1383-1397.,miriam.oses-ruiz@tsl.ac.uk,Δrpp1 mutant was increased in virulence.,M Osés-Ruiz 2021,2021,8 genes,Oses-Ruiz-2021-Appressorium-mediated plant infecti,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22873,PHI:124721,UniProt,G4MQB2,GenBank,EHA57305,,,70-15,rpp2 (MGG_09276),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,transcription factor,,,,increased virulence (hypervirulence),,,,,larger lesions,,,,,no,,,,,,,gene deletion: full,,,NN,34707224,PubMed,10.1038/s41564-021-00978-w,Nat Microbiol. 2021 Nov;6(11):1383-1397.,miriam.oses-ruiz@tsl.ac.uk,Δrpp2 mutant was increased in virulence.,M Osés-Ruiz 2021,2021,8 genes,Oses-Ruiz-2021-Appressorium-mediated plant infecti,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22874,PHI:124722,UniProt,G4MVH6,GenBank,EHA55802,,,70-15,rpp4 (MGG_07368),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,transcription factor,,,,increased virulence (hypervirulence),,,,,larger lesions,,,,,no,,,,,,,gene deletion: full,,,NN,34707224,PubMed,10.1038/s41564-021-00978-w,Nat Microbiol. 2021 Nov;6(11):1383-1397.,miriam.oses-ruiz@tsl.ac.uk,Δrpp4 mutant was increased in virulence.,M Osés-Ruiz 2021,2021,8 genes,Oses-Ruiz-2021-Appressorium-mediated plant infecti,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22875,PHI:124723,UniProt,G4MVN0,GenBank,EHA54139,,,70-15,rpp5 (MGG_08917),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,Leaves,transcription factor,,,,increased virulence (hypervirulence),,,,,larger lesions,,,,,no,,,,,,,gene deletion: full,,,NN,34707224,PubMed,10.1038/s41564-021-00978-w,Nat Microbiol. 2021 Nov;6(11):1383-1397.,miriam.oses-ruiz@tsl.ac.uk,Δrpp5 mutant was increased in virulence.,M Osés-Ruiz 2021,2021,8 genes,Oses-Ruiz-2021-Appressorium-mediated plant infecti,BATCH_133A,2024-05-01,MC,,,,,,,,,,,,,
,,Record 22876,PHI:124724,UniProt,A0A9P4Y0B6,GenBank,KAF3764052,,,EP155,Atg4 (XP_040775013.1),chromosome unknown,,,Atg8 (XP_040777207.1),UniProt: A0A9P4Y419; GenBank: KAF3766246,,5116,Cryphonectria parasitica,660469,EP155/2,chestnut blight,eudicots,60419,Castanea mollissima (related: chinese chestnut),,,,stem,autophagy related protein 4,,,,reduced virulence,,,,,small canker,reduced,,wild type ; aberrant,,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,34033505,PubMed,10.1094/PHYTO-01-21-0015-R,Phytopathology. 2022 Feb;112(2):299-307.,chenyaoj@gxu.edu.cn,"Parental KU80 strain incited large cankers on both apple and chestnut stem, very small cankers were incited by the Cpatf4 null mutant, comparable to the hypovirus-infected WT strain.",R Li 2022,2022,1 gene,Li-2022,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22877,PHI:124724,UniProt,A0A9P4Y0B6,GenBank,KAF3764052,,,EP155,Atg4 (XP_040775013.1),chromosome unknown,,,Atg8 (XP_040777207.1),UniProt: A0A9P4Y419; GenBank: KAF3766246,,5116,Cryphonectria parasitica,660469,EP155/2,chestnut blight,eudicots,3750,Malus domestica (related: apple),,,,fruit,autophagy related protein 4,,,,reduced virulence,,,,,small canker,reduced,,wild type ; aberrant,,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,34033505,PubMed,10.1094/PHYTO-01-21-0015-R,Phytopathology. 2022 Feb;112(2):299-307.,chenyaoj@gxu.edu.cn,"Parental KU80 strain incited large cankers on both apple and chestnut stem, very small cankers were incited by the Cpatf4 null mutant, comparable to the hypovirus-infected WT strain.",R Li 2022,2022,1 gene,Li-2022,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22878,PHI:124725,UniProt,A0A345CUS9,GenBank,AXF77196,,,Mdcuke,eop1 (AXF77196.1),,,,,,,65700,Erwinia tracheiphila,,MDCuke; SCR3,bacterial wilt,eudicots,3656,Cucumis melo (related: muskmelon),Athena,,,Seedlings,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34505816,PubMed,10.1094/MPMI-06-21-0149-R,Mol Plant Microbe Interact. 2021 Dec;34(12):1399-1408.,gbeattie@iastate.edu,Loss of eop1 did not alter the virulence of the mutants MDCukeΔeop1 and SCR3Δeop1 on muskmelon nor did it enable them to infect sqaush.,O I Olawole 2021,2021,3 genes,Olawole-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22879,PHI:124725,UniProt,A0A345CUS9,GenBank,AXF77196,,,Mdcuke,eop1 (AXF77196.1),,,,,,,65700,Erwinia tracheiphila,,MDCuke; SCR3,bacterial wilt,eudicots,3663,Curcubita pepo (related: zucchini),Partenon F1,,,Seedlings,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34505816,PubMed,10.1094/MPMI-06-21-0149-R,Mol Plant Microbe Interact. 2021 Dec;34(12):1399-1408.,gbeattie@iastate.edu,Loss of eop1 did not alter the virulence of the mutants MDCukeΔeop1 and SCR3Δeop1 on muskmelon nor did it enable them to infect sqaush.,O I Olawole 2021,2021,3 genes,Olawole-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22880,PHI:124726,UniProt,A0A0M2KAV7,GenBank,KKF36064,,,BuffGH,eop1 (WP_016191031.1),,,,,,,65700,Erwinia tracheiphila,,BHKY,bacterial wilt,eudicots,3656,Cucumis melo (related: muskmelon),Athena,,,Seedlings,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34505816,PubMed,10.1094/MPMI-06-21-0149-R,Mol Plant Microbe Interact. 2021 Dec;34(12):1399-1408.,gbeattie@iastate.edu,"Loss of eop1 from the Et-C1 strain BHKY, designated BHKYΔeop1, did not alter its virulence on either muskmelon or squash.",O I Olawole 2021,2021,3 genes,Olawole-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22881,PHI:124726,UniProt,A0A0M2KAV7,GenBank,KKF36064,,,BuffGH,eop1 (WP_016191031.1),,,,,,,65700,Erwinia tracheiphila,,BHKY,bacterial wilt,eudicots,3663,Curcubita pepo (related: zucchini),Partenon F1,,,Seedlings,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,34505816,PubMed,10.1094/MPMI-06-21-0149-R,Mol Plant Microbe Interact. 2021 Dec;34(12):1399-1408.,gbeattie@iastate.edu,"Loss of eop1 from the Et-C1 strain BHKY, designated BHKYΔeop1, did not alter its virulence on either muskmelon or squash.",O I Olawole 2021,2021,3 genes,Olawole-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22882,PHI:124725,UniProt,A0A345CUS9,GenBank,AXF77196,,,MDCuke,eop1 (AXF77196.1),,,,,,,65700,Erwinia tracheiphila,,MDCuke,bacterial wilt,eudicots,3656,Cucumis melo (related: muskmelon),Athena,,,Seedlings,effector protein,,,,effector (plant avirulence determinant),,,,,wild type,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,34505816,PubMed,10.1094/MPMI-06-21-0149-R,Mol Plant Microbe Interact. 2021 Dec;34(12):1399-1408.,gbeattie@iastate.edu,Expression of eop1 from MdCuke or BHKY in MDCukeΔeop1 did not alter virulence on muskmelon or enable infection of squash.,O I Olawole 2021,2021,3 genes,Olawole-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22883,PHI:124726,UniProt,A0A0M2KAV7,GenBank,KKF36064,,,BuffGH,eop1 (WP_016191031.1),,,,,,,65700,Erwinia tracheiphila,,BHKY,bacterial wilt,eudicots,3656,Cucumis melo (related: muskmelon),Athena,,,Seedlings,effector protein,,,,effector (plant avirulence determinant),,,,,high wilting symptoms,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,34505816,PubMed,10.1094/MPMI-06-21-0149-R,Mol Plant Microbe Interact. 2021 Dec;34(12):1399-1408.,gbeattie@iastate.edu,Expression of eop1MΔCuke in BHKY increased virulence on muskmelon.,O I Olawole 2021,2021,3 genes,Olawole-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22884,PHI:124727,UniProt,A0A345CUS7,GenBank,AXF77194,,,Mdcuke,DspE (AXF77194.1),,,,,,,65700,Erwinia tracheiphila,,MDCuke; SCR3,bacterial wilt,eudicots,3656,Cucumis melo (related: muskmelon),Athena,,,Seedlings,effector protein,,,,effector (plant avirulence determinant),,,,,low wilting symptoms,,,,,no,,,,,,,gene deletion: full,,,NN,34505816,PubMed,10.1094/MPMI-06-21-0149-R,Mol Plant Microbe Interact. 2021 Dec;34(12):1399-1408.,gbeattie@iastate.edu,Loss of ΔspE reduced the virulence of Et-melo strains MDCuke and SCR3 on muskmelon and cucumber.,O I Olawole 2021,2021,3 genes,Olawole-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22885,PHI:124727,UniProt,A0A345CUS7,GenBank,AXF77194,,,Mdcuke,DspE (AXF77194.1),,,,,,,65700,Erwinia tracheiphila,,MDCuke; SCR3,bacterial wilt,eudicots,3659,Cucumis sativus (related: cucumber),Marketmore,,,Seedlings,effector protein,,,,effector (plant avirulence determinant),,,,,low wilting symptoms,,,,,no,,,,,,,gene deletion: full,,,NN,34505816,PubMed,10.1094/MPMI-06-21-0149-R,Mol Plant Microbe Interact. 2021 Dec;34(12):1399-1408.,gbeattie@iastate.edu,Loss of ΔspE reduced the virulence of Et-melo strains MDCuke and SCR3 on muskmelon and cucumber.,O I Olawole 2021,2021,3 genes,Olawole-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22886,PHI:124727,UniProt,A0A345CUS7,GenBank,AXF77194,,,Mdcuke,DspE (AXF77194.1),,,,,,,65700,Erwinia tracheiphila,,MDCuke; SCR3,bacterial wilt,eudicots,3663,Curcubita pepo (related: zucchini),Partenon F1,,,Seedlings,effector protein,,,,effector (plant avirulence determinant),,,,,low wilting symptoms,,,,,no,,,,,,,gene deletion: full,,,NN,34505816,PubMed,10.1094/MPMI-06-21-0149-R,Mol Plant Microbe Interact. 2021 Dec;34(12):1399-1408.,gbeattie@iastate.edu,Loss of dspEF did not enable MDCuke or SCR3 to wilt squash.,O I Olawole 2021,2021,3 genes,Olawole-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22887,PHI:124278,UniProt,S0E184,GenBank,CCT66448,,,IMI 58289,Kmt5 (XP_023428529),chromosome FFUJ_chr03,,,,,,5127,Fusarium fujikuroi,1279085,IMI58289,bakanae disease,monocots,4530,Oryza sativa (related: rice),Nipponbare,,,Seedlings,H4K20 methyltransferase,,,,unaffected pathogenicity,,,,,typical bakanae symptoms,wild type,,wild type,,no,sorbitol;NaCl,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710,,,,,gene deletion: full ; gene complementation,,,NN,34214671,PubMed,10.1016/j.fgb.2021.103602,Fungal Genet Biol. 2021 Oct;155:103602.,lena.studt@boku.ac.at,"In the case of F. fujikuroi, Δffkmt5, FfKMT5Cis and OE::FfKMT5 caused typical bakanae symptoms (shoot elongation and chlorosis) on rice seedlings, and internode elongation did not deviate from FfWT-infected rice seedlings.",S Bachleitner 2021,2021,2 genes,Bachleitner-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22888,PHI:124278,UniProt,S0E184,GenBank,CCT66448,,,IMI 58289,Kmt5 (XP_023428529),chromosome FFUJ_chr03,,,,,,5127,Fusarium fujikuroi,1279085,IMI58289,bakanae disease,monocots,4530,Oryza sativa (related: rice),Nipponbare,,,Seedlings,H4K20 methyltransferase,,,,unaffected pathogenicity,,,,,typical bakanae symptoms,wild type,,wild type,,no,sorbitol;NaCl,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710,,,,,altered gene expression / gene regulation: overexpression,,,NN,34214671,PubMed,10.1016/j.fgb.2021.103602,Fungal Genet Biol. 2021 Oct;155:103602.,lena.studt@boku.ac.at,"In the case of F. fujikuroi, Δffkmt5, FfKMT5Cis and OE::FfKMT5 caused typical bakanae symptoms (shoot elongation and chlorosis) on rice seedlings, and internode elongation did not deviate from FfWT-infected rice seedlings.",S Bachleitner 2021,2021,2 genes,Bachleitner-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22889,PHI:124729,UniProt,Q4I8C9,GenBank,ESU12633,,,PH-1; NRRL 31084,Kmt5 (Q4I8C9),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4530,Oryza sativa (related: rice),Nipponbare,,,Wheat heads,H4K20 methyltransferase,,,,reduced virulence,,,,,lower infection rate,reduced,,reduced,,no,sorbitol;NaCl,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710,,,,,gene deletion: full ; gene complementation,,,NN,34214671,PubMed,10.1016/j.fgb.2021.103602,Fungal Genet Biol. 2021 Oct;155:103602.,lena.studt@boku.ac.at,"Lower infection rates were determined for Δfgkmt5 i.e., 84% of FgWT, whereas complemented and overexpressed strains reached 90.5% and 95%",S Bachleitner 2021,2021,2 genes,Bachleitner-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22890,PHI:124729,UniProt,Q4I8C9,GenBank,ESU12633,,,PH-1; NRRL 31084,Kmt5 (Q4I8C9),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4530,Oryza sativa (related: rice),Nipponbare,,,Wheat heads,H4K20 methyltransferase,,,,unaffected pathogenicity,,,,,wild type,reduced,,reduced,,no,sorbitol;NaCl,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710,,,,,altered gene expression / gene regulation: overexpression,,,NN,34214671,PubMed,10.1016/j.fgb.2021.103602,Fungal Genet Biol. 2021 Oct;155:103602.,lena.studt@boku.ac.at,"Lower infection rates were determined for Δfgkmt5 i.e., 84% of FgWT, whereas complemented and overexpressed strains reached 90.5% and 95%",S Bachleitner 2021,2021,2 genes,Bachleitner-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22891,PHI:124730,UniProt,A0A7J6JPA7,GenBank,KAF4491891,,,Nara gc5,Pmt4 (KAF4491891),,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,leaves,O-mannosyltransferase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38786685,PubMed,10.3390/jof10050330,J Fungi (Basel). 2024 May 1;10(5):330.,csuftlihe@163.com,Pathogenicity test showed that the lesion area in mutant strain ΔCfpmt4 was significantly less than the large and typical lesions caused by wild-type and ΔCfpmt4/ΔCfpmt4.,D Yang 2024,2024,1 gene,Yang-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22892,PHI:124730,UniProt,A0A7J6JPA7,GenBank,KAF4491891,,,Nara gc5,Pmt4 (KAF4491891),,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,O-mannosyltransferase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38786685,PubMed,10.3390/jof10050330,J Fungi (Basel). 2024 May 1;10(5):330.,csuftlihe@163.com,Pathogenicity test showed that the lesion area in mutant strain ΔCfpmt4 was significantly less than the large and typical lesions caused by wild-type and ΔCfpmt4/ΔCfpmt4.,D Yang 2024,2024,1 gene,Yang-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22893,PHI:124731,UniProt,A0A8S9CYB5,GenBank,KAE9575170,,,CGMCC3.17371,CE4 (XP_031884717.1),,,,,,,690256,Colletotrichum fructicola,,DSCF-02,anthracnose,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,,,no,,,,,,,functional test in host: transient expression,,,NN,38766536,PubMed,10.1093/hr/uhae078,Hortic Res. 2024 Mar 14;11(5):uhae078.,huanglili@nwafu.edu.cn,Transient expression of the four core effectors significantly shows limited infection.,M Han 2024,2024,4 genes,Han-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22894,PHI:124732,UniProt,A0A8S9CMM4,GenBank,KAE9571711,,,CGMCC3.17371,CE25 (XP_031881258.1),,,,,,,690256,Colletotrichum fructicola,,DSCF-02,anthracnose,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,,,no,,,,,,,functional test in host: transient expression,,,NN,38766536,PubMed,10.1093/hr/uhae078,Hortic Res. 2024 Mar 14;11(5):uhae078.,huanglili@nwafu.edu.cn,Transient expression of the four core effectors significantly shows limited infection.,M Han 2024,2024,4 genes,Han-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22895,PHI:124733,UniProt,A0A8S9DGP7,GenBank,KAE9582158,,,CGMCC3.17371,CE61 (XP_031891705.1),,,,,,,690256,Colletotrichum fructicola,,DSCF-02,anthracnose,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,,,no,,,,,,,functional test in host: transient expression,,,NN,38766536,PubMed,10.1093/hr/uhae078,Hortic Res. 2024 Mar 14;11(5):uhae078.,huanglili@nwafu.edu.cn,Transient expression of the four core effectors significantly shows limited infection.,M Han 2024,2024,4 genes,Han-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22896,PHI:124734,UniProt,A0A8S9D7B5,GenBank,KAE9579212,,,CGMCC3.17371,CE66 (XP_031888759.1),,,,,,,690256,Colletotrichum fructicola,,DSCF-02,anthracnose,eudicots,4100,Nicotiana benthamiana (no common name found),,,,leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,,,no,,,,,,,functional test in host: transient expression,,,NN,38766536,PubMed,10.1093/hr/uhae078,Hortic Res. 2024 Mar 14;11(5):uhae078.,huanglili@nwafu.edu.cn,Transient expression of the four core effectors significantly shows limited infection.,M Han 2024,2024,4 genes,Han-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22897,PHI:124735,UniProt,G4MR98,GenBank,EHA58223,,,70-15,Som1,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),Golden promise,,,leaves,cAMP dependent protein kinase A,,,cAMP PKA and Pmk1 MAPK pathway,loss of pathogenicity,,,,,no infection,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,34089626,PubMed,10.1111/cmi.13370,Cell Microbiol. 2021 Oct;23(10):e13370.,zhywang@zju.edu.cn,ΔMosom1 is non pathogenic compared to wild type.,Deng-2021,2021,1 gene,Deng-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22898,PHI:124735,UniProt,G4MR98,GenBank,EHA58223,,,70-15,Som1,chromosome 1,S151D (ΔMosom1/MoSOM1Δ151); S188D (ΔMosom1/MoSOM1Δ188); S512D (ΔMosom1/MoSOM1Δ512); S603D (ΔMosom1/MoSOM1Δ603); S629D (ΔMosom1/MoSOM1Δ629); S642D(ΔMosom1/MoSOM1Δ642); SOM1S228A-GFP; SOM1S227E-GFP; SOM1S228E-GFP; ΔMosom1/MoSOM1S227E (S7E -1),,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),Golden promise,,,leaves,cAMP dependent protein kinase A,,,cAMP PKA and Pmk1 MAPK pathway,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene mutation,,,NN,34089626,PubMed,10.1111/cmi.13370,Cell Microbiol. 2021 Oct;23(10):e13370.,zhywang@zju.edu.cn,"Typical lesions were observed on both intact and abraded barley leaves inoculated with the wild-type M. oryzae strain, Guy11, all the transformants were pathogenic on barley leaves same as wild type.",Deng-2021,2021,1 gene,Deng-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22899,PHI:124735,UniProt,G4MR98,GenBank,EHA58223,,,70-15,Som1,chromosome 1,"S7/8D (ΔMosom1/MoSOM1Δ227,228); SOM1S227A-GFP; ΔMosom1/MoSOM1S227A (S7A-3); ΔMosom1/MoSOM1S227V (SV-5 and SV-6); ΔMosom1/MoSOM1S227Y (SY-6)",,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),Golden promise,,,leaves,cAMP dependent protein kinase A,,,cAMP PKA and Pmk1 MAPK pathway,loss of pathogenicity,,,,,no infection,reduced,,reduced,,no,,,,,,,gene mutation,,,NN,34089626,PubMed,10.1111/cmi.13370,Cell Microbiol. 2021 Oct;23(10):e13370.,zhywang@zju.edu.cn,"Typical lesions were observed on both intact and abraded barley leaves inoculated with the wild-type M. oryzae strain, Guy11, ΔMosom1 and S7A-3 mutants, transformants SV-5, SV-6 and SY-5 and all mutants were non-pathogenic on barley leaves.",Deng-2021,2021,1 gene,Deng-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22900,PHI:124735,UniProt,G4MR98,GenBank,EHA58223,,,70-15,Som1,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,cAMP dependent protein kinase A,,,cAMP PKA and Pmk1 MAPK pathway,loss of pathogenicity,,,,,no infection,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,34089626,PubMed,10.1111/cmi.13370,Cell Microbiol. 2021 Oct;23(10):e13370.,zhywang@zju.edu.cn,ΔMosom1 is non pathogenic compared to wild type.,Deng-2021,2021,1 gene,Deng-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22901,PHI:124735,UniProt,G4MR98,GenBank,EHA58223,,,70-15,Som1,chromosome 1,ΔMosom1/MoSOM1S227E (S7E -1),,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),CO39,,,leaves,cAMP dependent protein kinase A,,,cAMP PKA and Pmk1 MAPK pathway,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene mutation,,,NN,34089626,PubMed,10.1111/cmi.13370,Cell Microbiol. 2021 Oct;23(10):e13370.,zhywang@zju.edu.cn,"Typical lesions were observed on both intact and abraded barley leaves inoculated with the wild-type M. oryzae strain, Guy11, S7E-1 was pathogenic on rice leaves same as wild type.",Deng-2021,2021,1 gene,Deng-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22902,PHI:124735,UniProt,G4MR98,GenBank,EHA58223,,,70-15,Som1,chromosome 1,"S7/8D (ΔMosom1/MoSOM1Δ227,228); SOM1S227A-GFP; ΔMosom1/MoSOM1S227A (S7A-3); ΔMosom1/MoSOM1S227V (SV-5 and SV-6); ΔMosom1/MoSOM1S227Y (SY-6)",,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,cAMP dependent protein kinase A,,,cAMP PKA and Pmk1 MAPK pathway,loss of pathogenicity,,,,,no infection,reduced,,reduced,,no,,,,,,,gene mutation,,,NN,34089626,PubMed,10.1111/cmi.13370,Cell Microbiol. 2021 Oct;23(10):e13370.,zhywang@zju.edu.cn,"Typical lesions were observed on both intact and abraded barley leaves inoculated with the wild-type M. oryzae strain, Guy11, ΔMosom1 and S7A-3 mutants, transformants SV-5, SV-6 and SY-5 were non-pathogenic on rice leaves.",Deng-2021,2021,1 gene,Deng-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22903,PHI:124736,UniProt,Q8Y282,GenBank,CAD13982,,,GMI1000,RSc0454,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1 (RK5050),bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),,,,Seedlings,FAD-linked oxidase,,,,loss of pathogenicity,,,,,no symptom,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34374557,PubMed,10.1094/MPMI-07-21-0168-SC,Mol Plant Microbe Interact. 2021 Nov;34(11):1228-1235.,bioyongzhang@swu.edu.cn,"RSc0454 mutants shows diminished growth in the minimal medium, and lost pathogenicity toward host plant.",M Chen 2021,2021,1 gene,Chen-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22904,PHI:124736,UniProt,Q8Y282,GenBank,CAD13982,,,GMI1000,RSc0454,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1 (RK5050),bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Seedlings,FAD-linked oxidase,,,,loss of pathogenicity,,,,,no symptom,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34374557,PubMed,10.1094/MPMI-07-21-0168-SC,Mol Plant Microbe Interact. 2021 Nov;34(11):1228-1235.,bioyongzhang@swu.edu.cn,"RSc0454 mutants shows diminished growth in the minimal medium, and lost pathogenicity toward host plant.",M Chen 2021,2021,1 gene,Chen-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22905,PHI:124737,UniProt,V6REE9,GenBank,CEF83475,,,PH-1,Bmh1 (FGSG_06847),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,coleoptiles,14-3-3 protein,,,,reduced virulence,,,,,smaller lesions,,wild type,reduced,,no,sorbitol;NaCl,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710,,,,,gene deletion: full ; gene complementation,,,NN,34156266,PubMed,10.1094/PHYTO-05-21-0214-R,Phytopathology. 2022 Feb;112(2):290-298.,mgzhou@njau.edu.cn,All three deletion mutants showed reduced virulence on wheat coleoptiles.,L Ren 2022,2022,3 genes,Ren-2022,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22906,PHI:124738,UniProt,I1RCU1,GenBank,CEF73553,,,PH-1,Bmh2 (FGSG_01421),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,coleoptiles,14-3-3 protein,,,,reduced virulence,,,,,smaller lesions,,wild type,reduced,,no,sorbitol;NaCl,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710,,,,,gene deletion: full ; gene complementation,,,NN,34156266,PubMed,10.1094/PHYTO-05-21-0214-R,Phytopathology. 2022 Feb;112(2):290-298.,mgzhou@njau.edu.cn,All three deletion mutants showed reduced virulence on wheat coleoptiles.,L Ren 2022,2022,3 genes,Ren-2022,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22907,PHI:124739,UniProt,A0A0E0RVC1,GenBank,CEF75196,,,PH-1,Nth (FGSG_09895),chromosome 1,,,Bmh1 (FGSG_06847); Bmh2 (FGSG_01421),UniProt: V6REE9; GenBank: CEF83475; UniProt: I1RCU1; GenBank: CEF73553,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),,,,coleoptiles,trehalase,,,,reduced virulence,,,,,smaller lesions,,wild type,reduced,,no,sorbitol;NaCl,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710,,,,,gene deletion: full ; gene complementation,,,NN,34156266,PubMed,10.1094/PHYTO-05-21-0214-R,Phytopathology. 2022 Feb;112(2):290-298.,mgzhou@njau.edu.cn,All three deletion mutants showed reduced virulence on wheat coleoptiles.,L Ren 2022,2022,3 genes,Ren-2022,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22908,PHI:124740,UniProt,B8N5B2,GenBank,QRD90340,,,NRRL 3357,Atg8 (XP_002376260.1),chromosome 4,,,,,,5059,Aspergillus flavus,332952,NRRL3357,ear rot in corn and yellow mold in peanuts,monocots,4577,Zea mays (related: maize),,,,kernel,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,increased,reduced,no,hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38786704,PubMed,10.3390/jof10050349,J Fungi (Basel). 2024 May 13;10(5):349.,pengxue@jsnu.edu.cn,"Deletion of atg8 showed a significant decrease in conidiation, spore germination, sclerotia formation and virulence compared to the WT and atg8C strains.",Q Geng 2024,2024,1 gene,Geng-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22909,PHI:124740,UniProt,B8N5B2,GenBank,QRD90340,,,NRRL 3357,Atg8 (XP_002376260.1),chromosome 4,,,,,,5059,Aspergillus flavus,332952,NRRL3357,ear rot in corn and yellow mold in peanuts,monocots,3818,Arachis hypogaea (related: peanut),,,,seeds,autophagy-related protein,,,,reduced virulence,,,,,,reduced,,increased,reduced,no,hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38786704,PubMed,10.3390/jof10050349,J Fungi (Basel). 2024 May 13;10(5):349.,pengxue@jsnu.edu.cn,"Deletion of atg8 showed a significant decrease in conidiation, spore germination, sclerotia formation and virulence compared to the WT and atg8C strains.",Q Geng 2024,2024,1 gene,Geng-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22910,PHI:124741,UniProt,A4RF61,GenBank,EHA49028,,,70-15,hse1 (MGG_00455),chromosome 5,,,vps27,UniProt: A4QTV1; GenBank: EHA52647,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,class E vacuolar protein-sorting machinery protein HSE1,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,34472190,PubMed,10.1111/1462-2920.15753,Environ Microbiol. 2022 Mar;24(3):1076-1092.,fuchenglin@zju.edu.cn,"Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves.",L X Sun 2022,2022,2 genes,Sun-2022,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22911,PHI:124742,UniProt,A4QTV1,GenBank,EHA52647,,,70-15,vps27 (MGG_04958),chromosome 3,,,hse1; vps23,UniProt: A4RF61; GenBank: EHA49028,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,vacuolar protein sorting-associated protein 27,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,34472190,PubMed,10.1111/1462-2920.15753,Environ Microbiol. 2022 Mar;24(3):1076-1092.,fuchenglin@zju.edu.cn,"Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves.",L X Sun 2022,2022,2 genes,Sun-2022,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22912,PHI:124741,UniProt,A4RF61,GenBank,EHA49028,,,70-15,hse1 (MGG_00455),chromosome 5,,,vps27,UniProt: A4QTV1; GenBank: EHA52647,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),,,,leaves,class E vacuolar protein-sorting machinery protein HSE1,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,34472190,PubMed,10.1111/1462-2920.15753,Environ Microbiol. 2022 Mar;24(3):1076-1092.,fuchenglin@zju.edu.cn,"Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves.",L X Sun 2022,2022,2 genes,Sun-2022,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22913,PHI:124742,UniProt,A4QTV1,GenBank,EHA52647,,,70-15,vps27 (MGG_04958),chromosome 3,,,hse1; vps23,UniProt: A4RF61; GenBank: EHA49028,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4513,Hordeum vulgare (related: barley),,,,leaves,vacuolar protein sorting-associated protein 27,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,34472190,PubMed,10.1111/1462-2920.15753,Environ Microbiol. 2022 Mar;24(3):1076-1092.,fuchenglin@zju.edu.cn,"Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves.",L X Sun 2022,2022,2 genes,Sun-2022,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22914,PHI:124743,UniProt,G4MY59,GenBank,EHA54390,,,70-15,Kin1,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Ku80,rice blast,monocots,4530,Oryza sativa (related: rice),CO-39,,,leaves,protein kinase,,,signalling pathway,reduced virulence,,,,,fewer disease spots,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38714914,PubMed,10.1186/s12864-024-10337-8,BMC Genomics. 2024 May 7;25(1):449.,linyachun@jxau.edu.cn,ΔMokin1 mutant showed significant phenotypic defects and significantly reduced pathogenicity.,L Zhang 2024,2024,1 gene,Zhang-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22915,PHI:124744,UniProt,A0A384JHX6,GenBank,ATZ50179,,,B05.10,wcl2 (Bcin05g05530.1),chromosome BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3885,Phaseolus vulgaris (related: string bean),,,,leaves,white collar 2,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869,,,,,gene deletion: full ; gene complementation,,,NN,38814088,PubMed,10.1128/mbio.00133-24,mBio. 2024 May 30:e0013324.,xu@bio.ecnu.edu.cn,"Δbcwcl2 mutant was less virulent than the WT, while its virulence defect was rectified by complementation with the intact Bcwcl2 gene",W Ren 2024,2024,1 gene,Ren-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22916,PHI:124744,UniProt,A0A384JHX6,GenBank,ATZ50179,,,B05.10,wcl2 (Bcin05g05530.1),chromosome BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,4081,Solanum lycopersicum (related: tomato),M82,,,leaves,white collar 2,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869,,,,,gene deletion: full ; gene complementation,,,NN,38814088,PubMed,10.1128/mbio.00133-24,mBio. 2024 May 30:e0013324.,xu@bio.ecnu.edu.cn,"Δbcwcl2 mutant was less virulent than the WT, while its virulence defect was rectified by complementation with the intact Bcwcl2 gene",W Ren 2024,2024,1 gene,Ren-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22917,PHI:124744,UniProt,A0A384JHX6,GenBank,ATZ50179,,,B05.10,wcl2 (Bcin05g05530.1),chromosome BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3750,Malus domestica (related: apple),,,,fruit,white collar 2,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869,,,,,gene deletion: full ; gene complementation,,,NN,38814088,PubMed,10.1128/mbio.00133-24,mBio. 2024 May 30:e0013324.,xu@bio.ecnu.edu.cn,"Δbcwcl2 mutant was less virulent than the WT, while its virulence defect was rectified by complementation with the intact Bcwcl2 gene",W Ren 2024,2024,1 gene,Ren-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22918,PHI:124744,UniProt,A0A384JHX6,GenBank,ATZ50179,,,B05.10,wcl2 (Bcin05g05530.1),chromosome BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,23211,Pyrus communis (related: pear),,,,fruit,white collar 2,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869,,,,,gene deletion: full ; gene complementation,,,NN,38814088,PubMed,10.1128/mbio.00133-24,mBio. 2024 May 30:e0013324.,xu@bio.ecnu.edu.cn,"Δbcwcl2 mutant was less virulent than the WT, while its virulence defect was rectified by complementation with the intact Bcwcl2 gene",W Ren 2024,2024,1 gene,Ren-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22919,PHI:124744,UniProt,A0A384JHX6,GenBank,ATZ50179,,,B05.10,wcl2 (Bcin05g05530.1),chromosome BCIN05,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3663,Curcubita pepo (related: zucchini),,,,fruit,white collar 2,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869,,,,,gene deletion: full ; gene complementation,,,NN,38814088,PubMed,10.1128/mbio.00133-24,mBio. 2024 May 30:e0013324.,xu@bio.ecnu.edu.cn,"Δbcwcl2 mutant was less virulent than the WT, while its virulence defect was rectified by complementation with the intact Bcwcl2 gene",W Ren 2024,2024,1 gene,Ren-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22920,PHI:124745,UniProt,A0A0D1E921,GenBank,KIS71881,,,521,row1 (Umag_00309),chromosome 1,,,,,,5270,Ustilago maydis,,"CL13, SG200, FB1xFB2",smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,secretory pathway,reduced virulence,,,yes,,less symptoms,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;tunicamycin;glucose;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;tunicamycin: CHEBI:29699; ;glucose: CHEBI:17234; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,All mutants except Δrow3 had reduced virulence compared to the WT,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22921,PHI:124746,UniProt,A0A0D1E4Y8,GenBank,KIS71044,,,521,row2 (Umag_00961),chromosome 2,,,,,,5270,Ustilago maydis,,CL13,smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,secretory pathway,reduced virulence,,,,,less symptoms,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;tunicamycin;glucose;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;tunicamycin: CHEBI:29699; ;glucose: CHEBI:17234; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,All mutants except Δrow3 had reduced virulence compared to the WT,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22922,PHI:124747,UniProt,A0A0D1DZA9,GenBank,KIS68936,,,521,row3 (Umag_02921),chromosome 7,,,,,,5270,Ustilago maydis,,CL13,smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;tunicamycin;glucose;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;tunicamycin: CHEBI:29699; ;glucose: CHEBI:17234; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,All mutants except Δrow3 had reduced virulence compared to the WT,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22923,PHI:124748,UniProt,A0A0D1CN74,GenBank,KIS68078,,,521,row4 (Umag_10474),chromosome 10,,,,,,5270,Ustilago maydis,,CL13,smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,,reduced virulence,,,,,less symptoms,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;tunicamycin;glucose;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;tunicamycin: CHEBI:29699; ;glucose: CHEBI:17234; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,All mutants except Δrow3 had reduced virulence compared to the WT,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22924,PHI:124749,UniProt,A0A0D1BUJ8,GenBank,KIS65782,,,521,row5 (Umag_06162),chromosome 22,,,,,,5270,Ustilago maydis,,CL13,smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,,reduced virulence,,,,,less symptoms,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;tunicamycin;glucose;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;tunicamycin: CHEBI:29699; ;glucose: CHEBI:17234; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,All mutants except Δrow3 had reduced virulence compared to the WT,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22925,PHI:124750,UniProt,A0A0D1CQ73,GenBank,KIS68783,,,521,row6 (Umag_03349),chromosome 8,,,,,,5270,Ustilago maydis,,CL13,smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,,reduced virulence,,,,,less symptoms,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;tunicamycin;glucose;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;tunicamycin: CHEBI:29699; ;glucose: CHEBI:17234; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,All mutants except Δrow3 had reduced virulence compared to the WT,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22926,PHI:124745,UniProt,A0A0D1E921,GenBank,KIS71881,,,521,row1 (Umag_00309),chromosome 1,,,,,PHI:124746,5270,Ustilago maydis,,"CL13, SG200, FB1xFB2",smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,secretory pathway,reduced virulence,,,,,less symptoms,,,,,no,,,,,,,gene deletion: full,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,Δrow1Δrow2 double mutant caused significantly less severe symptoms in infected maize plants than did single mutants.,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22927,PHI:124746,UniProt,A0A0D1E4Y8,GenBank,KIS71044,,,521,row2 (Umag_00961),chromosome 2,,,,,PHI:124745,5270,Ustilago maydis,,CL13,smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,secretory pathway,reduced virulence,,,,,less symptoms,,,,,no,,,,,,,gene deletion: full,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,Δrow1Δrow2 double mutant caused significantly less severe symptoms in infected maize plants than did single mutants.,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22928,PHI:124745,UniProt,A0A0D1E921,GenBank,KIS71881,,,521,row1 (Umag_00309),chromosome 1,,,,,PHI:124746; PHI:124748,5270,Ustilago maydis,,"CL13, SG200, FB1xFB2",smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,secretory pathway,reduced virulence,,,,,less symptoms,,,,,no,,,,,,,gene deletion: full,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,The triple mutant Δrow1Δrow2Δrow4 even showed less severe symptoms than the double mutant.,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22929,PHI:124746,UniProt,A0A0D1E4Y8,GenBank,KIS71044,,,521,row2 (Umag_00961),chromosome 2,,,,,PHI:124745; PHI:124748,5270,Ustilago maydis,,CL13,smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,secretory pathway,reduced virulence,,,,,less symptoms,,,,,no,,,,,,,gene deletion: full,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,The triple mutant Δrow1Δrow2Δrow4 even showed less severe symptoms than the double mutant.,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22930,PHI:124748,UniProt,A0A0D1CN74,GenBank,KIS68078,,,521,row4 (Umag_10474),chromosome 10,,,,,PHI:124745; PHI:124746,5270,Ustilago maydis,,CL13,smut disease,monocots,4577,Zea mays (related: maize),Early Golden Bantam,,,leaves,uncharacterized protein,,,,reduced virulence,,,,,less symptoms,,,,,no,,,,,,,gene deletion: full,,,NN,38742361,PubMed,10.1111/nph.19798,New Phytol. 2024 May 14.,rrambar@upo.es,The triple mutant Δrow1Δrow2Δrow4 even showed less severe symptoms than the double mutant.,M D Pejenaute-Ochoa 2024,2024,6 genes,Pejenaute-Ochoa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22931,PHI:124751,UniProt,A0A0U5FL50,GenBank,CEG19069,,,,xanB,,,,,,,611301,Xanthomonas citri,,subsp. Citri,Citrus canker,eudicots,159033,Citrus aurantiifolia (related: lime),,,,leaves,GDP-mannose pyrophosphorylase,,,,reduced virulence,,,,,less symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38722158,PubMed,10.1128/spectrum.03673-23,Microbiol Spectr. 2024 Jun 4;12(6):e0367323.,tomich@fcfrp.usp.br,"The wild-type Xcc strain induced the typical citrus canker symptoms, whereas the deletion of xanB reduced pathogenicity for XccΔxanB in both infiltration and spray inoculation.",A V Alexandrino 2024,2024,1 gene,Alexandrino-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22932,PHI:124752,UniProt,Q1PBD2,GenBank,ABE67098,,,,gbb1,,,,,,,117187,Fusarium verticillioides,334819,7600,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,kernels,G protein β subunit,,,G-protein signaling pathway,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,34165327,PubMed,10.1094/MPMI-09-20-0250-R,Mol Plant Microbe Interact. 2021 Oct;34(10):1157-1166.,kolomiets@tamu.edu,"""The Δgbb1 mutant strain displayed significantly reduced coloniza tion, as evidenced by visually less fungal mycelia growth on the kernel and lower ergosterol content in infected kernels.""",Y S Park 2021,2021,1 gene,Park-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22933,PHI:124753,UniProt,Q8XYF2,GenBank,CAD15508,,,GMI1000,RSc1806,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Ohgata-Fukuju,,,Seedlings,polyketide synthase protein,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full,,,NN,38805410,PubMed,10.1094/MPMI-12-23-0203-R,Mol Plant Microbe Interact. 2024 May;37(5):467-476.,yhikichi@kochi-u.ac.jp,The tomato plants inoculated with OE1-1 were wilted at 4 days after inoculation and were dead by 8 DAI; where as RSc 1806 mutant was not virulent at 4 days and then shows decreased wilting symptoms at 8 DAI.,Y Terazawa 2024,2024,1 gene,Terazawa-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22934,PHI:124754,UniProt,A0A194V9F2,GenBank,KUI60441,,,SXYL134,Smt3,chromosome unknown,,,,,,5116,Cryphonectria parasitica,660469,EP155/2,chestnut blight,eudicots,60419,Castanea mollissima (related: chinese chestnut),,,,Stems,ubiquitin-like protein SMT3,,,,reduced virulence,,,,,smaller canker,reduced,,reduced,,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38784801,PubMed,10.3389/fmicb.2024.1391855,Front Microbiol. 2024 May 9;15:1391855.,"""liruonly@163.com ""","Deletion of the CpSmt3 gene resulted in defects in mycelial growth, hyphal morphology, suppression of sporulation and attenuation of virulence.",S Li 2024,2024,1 gene,Li-2024,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22935,PHI:124755,UniProt,A0A1C3YI80,GenBank,SCB64199,,,PH-1,Cot1 (FGSG_01188),chromosome 1,,,Mob2 (FGSG_00518),UniProt: I1RAI8; GenBank: CEF72461,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Jimai 22,,,Spikelets; Corn silk; Leaves,NDR kinase,,,,reduced virulence,,,,,no scab symptoms,reduced,reduced,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34347361,PubMed,10.1111/1462-2920.15698,Environ Microbiol. 2021 Sep;23(9):5505-5524.,chenyun0927@zju.edu.cn,"ΔFgcot1 and ΔFgmob2 exhibited serious defects in hyphal growth, polarity, fungal development and cell wall integrity as well as reduced virulence in planta.",N Liu 2021,2021,2 genes,Liu-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22936,PHI:124756,UniProt,I1RAI8,GenBank,CEF72461,,,PH-1,Mob2 (FGSG_00518),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Jimai 22,,,Spikelets; Corn silk; Leaves,NDR kinase activator,,,,reduced virulence,,,,,no scab symptoms,reduced,reduced,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34347361,PubMed,10.1111/1462-2920.15698,Environ Microbiol. 2021 Sep;23(9):5505-5524.,chenyun0927@zju.edu.cn,"ΔFgcot1 and ΔFgmob2 exhibited serious defects in hyphal growth, polarity, fungal development and cell wall integrity as well as reduced virulence in planta.",N Liu 2021,2021,2 genes,Liu-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22937,PHI:124757,UniProt,R0IY36,GenBank,EOA89645,,,Et28A,MR1 (XM_008024267.1),chromosome unknown,,,,,,93612,Setosphaeria turcica,,01-23,northern corn leaf blight,monocots,4577,Zea mays (related: maize),B73; 13-1077,,,Leaves,zinc finger protein,,,DHN melanin synthesis pathway,reduced virulence,,,yes,,,reduced,,reduced ; aberrant,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34278632,PubMed,10.1111/mmi.14786,Mol Microbiol. 2022 Feb;117(2):261-273.,caozhiyan@hebau.edu.cn,"The pathogenicity of ΔStmr1 was greatly reduced, as the disease spot area caused by ΔStmr1 was smaller than that of WT at 20 days.",Z Zhang 2022,2022,1 gene,Zhang-2022,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22938,PHI:124758,UniProt,A0A0A2JQN4,GenBank,KGO57727,,,MD-8,MetR,,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicot,3750,Malus domestica (related: apple),,,,fruit,bZip transcription factor,,,sulfur assimilation pathway,loss of pathogenicity,,,,,no necrotic lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34347341,PubMed,10.1111/1462-2920.15704,Environ Microbiol. 2021 Sep;23(9):5555-5568.,tsp@ibcas.ac.cn,"ΔPeMetR mutant could not develop any necrotic lesions on all test fruits, while the wild type and the complemented strains caused typical soft and watery lesions on the fruits.",Y Chen 2021,2021,1 gene,Chen-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22939,PHI:124758,UniProt,A0A0A2JQN4,GenBank,KGO57727,,,MD-8,MetR,,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicot,23211,Pyrus communis (related: pear),,,,fruit,bZip transcription factor,,,sulfur assimilation pathway,loss of pathogenicity,,,,,no necrotic lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34347341,PubMed,10.1111/1462-2920.15704,Environ Microbiol. 2021 Sep;23(9):5555-5568.,tsp@ibcas.ac.cn,"ΔPeMetR mutant could not develop any necrotic lesions on all test fruits, while the wild type and the complemented strains caused typical soft and watery lesions on the fruits.",Y Chen 2021,2021,1 gene,Chen-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22940,PHI:124758,UniProt,A0A0A2JQN4,GenBank,KGO57727,,,MD-8,MetR,,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicot,323851,Prunus persica var. nucipersica (related: nectarines),,,,fruit,bZip transcription factor,,,sulfur assimilation pathway,loss of pathogenicity,,,,,no necrotic lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34347341,PubMed,10.1111/1462-2920.15704,Environ Microbiol. 2021 Sep;23(9):5555-5568.,tsp@ibcas.ac.cn,"ΔPeMetR mutant could not develop any necrotic lesions on all test fruits, while the wild type and the complemented strains caused typical soft and watery lesions on the fruits.",Y Chen 2021,2021,1 gene,Chen-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22941,PHI:124758,UniProt,A0A0A2JQN4,GenBank,KGO57727,,,MD-8,MetR,,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicot,3758,Prunus domestica (related: plum),,,,fruit,bZip transcription factor,,,sulfur assimilation pathway,loss of pathogenicity,,,,,no necrotic lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34347341,PubMed,10.1111/1462-2920.15704,Environ Microbiol. 2021 Sep;23(9):5555-5568.,tsp@ibcas.ac.cn,"ΔPeMetR mutant could not develop any necrotic lesions on all test fruits, while the wild type and the complemented strains caused typical soft and watery lesions on the fruits.",Y Chen 2021,2021,1 gene,Chen-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22942,PHI:124758,UniProt,A0A0A2JQN4,GenBank,KGO57727,,,MD-8,MetR,,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicot,29760,Vitis vinifera (related: wine grape),,,,fruit,bZip transcription factor,,,sulfur assimilation pathway,loss of pathogenicity,,,,,no necrotic lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,34347341,PubMed,10.1111/1462-2920.15704,Environ Microbiol. 2021 Sep;23(9):5555-5568.,tsp@ibcas.ac.cn,"ΔPeMetR mutant could not develop any necrotic lesions on all test fruits, while the wild type and the complemented strains caused typical soft and watery lesions on the fruits.",Y Chen 2021,2021,1 gene,Chen-2021,BATCH_134,2024-06-01,MC,,,,,,,,,,,,,
,,Record 22943,PHI:124759,UniProt,A0A854CR10,GenBank,OLG95104,,,BXO512,ClpA,,,,,,,347,Xanthomonas oryzae,,pv. Oryzae; strain ZJ173,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24,,,Leaves,ATP-dependent Clp protease,,,histidine utilization pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33973800,PubMed,10.1094/PHYTO-01-21-0011-R,Phytopathology. 2021 Nov;111(11):2030-2040.,mgzhou@njau.edu.cn,The reduced lesions formed on rice leaves that were inoculated with ΔClpA than the Zj173 and complementary.,Y Ni 2021,2021,4 genes,Ni-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22944,PHI:124760,UniProt,A0A8E2YR63,GenBank,QBN99522,,,BXO512,ClpB,,,,,,,347,Xanthomonas oryzae,,pv. Oryzae; strain ZJ173,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24,,,Leaves,ATP-dependent Clp protease,,,histidine utilization pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33973800,PubMed,10.1094/PHYTO-01-21-0011-R,Phytopathology. 2021 Nov;111(11):2030-2040.,mgzhou@njau.edu.cn,The reduced lesions formed on rice leaves that were inoculated with ΔClpB than the Zj173 and complementary.,Y Ni 2021,2021,4 genes,Ni-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22945,PHI:124761,UniProt,Q2P6Z0,GenBank,BAE67687,,,MAFF 311018,ClpP,,,,,,,347,Xanthomonas oryzae,,pv. Oryzae; strain ZJ173,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24,,,Leaves,ATP-dependent Clp protease,,,histidine utilization pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33973800,PubMed,10.1094/PHYTO-01-21-0011-R,Phytopathology. 2021 Nov;111(11):2030-2040.,mgzhou@njau.edu.cn,The reduced lesions formed on rice leaves that were inoculated with ΔClpP than the Zj173 and complementary.,Y Ni 2021,2021,4 genes,Ni-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22946,PHI:124762,UniProt,B2SMI2,GenBank,ACD60767,,,PXO99A,ClpX,,,,,,,347,Xanthomonas oryzae,,pv. Oryzae; strain ZJ173,leaf blight,monocots,4530,Oryza sativa (related: rice),IR24,,,Leaves,ATP-dependent Clp protease,,,histidine utilization pathway,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33973800,PubMed,10.1094/PHYTO-01-21-0011-R,Phytopathology. 2021 Nov;111(11):2030-2040.,mgzhou@njau.edu.cn,The reduced lesions formed on rice leaves that were inoculated with ΔClpX than the Zj173 and complementary.,Y Ni 2021,2021,4 genes,Ni-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22947,PHI:124763,UniProt,A0A0C5UXJ7,GenBank,QEO96549,,,GX01,TfmR (XOCgx_1556),,,,,,,347,Xanthomonas oryzae,,pv. oryzicola GX01,leaf blight,monocots,4530,Oryza sativa (related: rice),Nipponbare,,,Leaves,transcriptional regulator,,,,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38892073,PubMed,10.3390/ijms25115887,Int J Mol Sci. 2024 May 28;25(11):5887.,ruifangli@gxaas.net,Lesions induced by ΔtfmR were significantly shorter compared to the wild type,Z Chang 2024,2024,1 gene,Chang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22948,PHI:124764,UniProt,G4N058,GenBank,EHA53093,,,70-15,Lpaat (XP_003712900.1,chromosome 3,,,,,,318829,Magnaporthe oryzae,1348879,B157,rice blast,monocots,4530,Oryza sativa (related: rice),,,,Leaves,lysophosphatidic acid acyltransferase,,,ferroptosis pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,38956897,PubMed,10.1111/mpp.13489,Mol Plant Pathol. 2024 Jul;25(7):e13489.,dengyz@scau.edu.cn,The lpaatΔ mutant showed an obvious decrease in mycelial colony diameter and conidia production and displayed an obvious defect in pathogenicity.,Q Liu 2024,2024,1 gene,Liu-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22949,PHI:124764,UniProt,G4N058,GenBank,EHA53093,,,70-15,Lpaat (XP_003712900.1,chromosome 3,,,,,,318829,Magnaporthe oryzae,1348879,B157,rice blast,monocots,4530,Oryza sativa (related: rice),,,,Leaves,lysophosphatidic acid acyltransferase,,,ferroptosis pathway,unaffected pathogenicity,,,,,wild type,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,38956897,PubMed,10.1111/mpp.13489,Mol Plant Pathol. 2024 Jul;25(7):e13489.,dengyz@scau.edu.cn,"The lpaat OE strain displayed no obvious difference in mycelial growth, conidia production or pathogenicity compared to the WT.",Q Liu 2024,2024,1 gene,Liu-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22950,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Br48,rice blast,monocots,4565,Triticum aestivum (related: bread wheat),Norin 4 (N4),,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,The disruption of ACE1Br48 in Br48 and the reintroduction of ACE1Br48 to the disruptant resulted in the reduction on N4,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22951,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Br48,rice blast,monocots,4513,Hordeum vulgare (related: barley),H.E.S.4,,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,The disruption of ACE1Br48 in Br48 and the reintroduction of ACE1Br48 to the disruptant resulted in the reduction on H.E.S.4,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22952,PHI:124766,UniProt,G4MWB5,GenBank,EHA55875,,,70-15,SYN2 (MGG_15097),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Br48,rice blast,monocots,4565,Triticum aestivum (related: bread wheat),Norin 4 (N4),,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Deletion of SYN2Br48 reduced its virulence on N4,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22953,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Ken53-33,rice blast,monocots,4530,Oryza sativa (related: rice),Aichi-asahi,,,Leaves,secondary metabolite gene cluster,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Disruption of ACE1 alleles of Ken53-33 and IN77- 20-1-1 showed no effect on their aggressiveness on rice.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22954,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Ken53-33,rice blast,monocots,4513,Hordeum vulgare (related: barley),H.E.S.4,,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Disruption of ACE1 alleles of Ken53-33 and IN77- 20-1-1 showed reduced effect on their aggressiveness on barley.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22955,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,IN77-20-1-1,rice blast,monocots,4555,Setaria italica (related: foxit millet),Aka-awa,,,Leaves,secondary metabolite gene cluster,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Disruption of ACE1 alleles of Ken53-33 and IN77- 20-1-1 showed no effect on their aggressiveness on foxit millet.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22956,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,IN77-20-1-1,rice blast,monocots,4513,Hordeum vulgare (related: barley),Nigrate,,,Leaves,secondary metabolite gene cluster,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Disruption of ACE1 alleles of Ken53-33 and IN77- 20-1-1 showed reduced effect on their aggressiveness on barley.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22957,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,MZ5-1-6,rice blast,monocots,4511,Eleusine coracana (related: foxit millet),Purna,,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Disruption of ACE1 alleles of MZ5-1-6 showed reduced effect on their aggressiveness on foxtail millet.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22958,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,MZ5-1-6,rice blast,monocots,4513,Hordeum vulgare (related: barley),H.E.S.4,,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Disruption of ACE1 alleles of MZ5-1-6 showed reduced effect on their aggressiveness on barley.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22959,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,TP2,rice blast,monocots,4522,Lolium perenne (related: perennial ryegrass),Friend,,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Disruption of ACE1 alleles of TP2 showed reduced effect on their aggressiveness on perennial ryegrass.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22960,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,TP2,rice blast,monocots,4513,Hordeum vulgare (related: barley),H.E.S.4,,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Disruption of ACE1 alleles of TP2 showed reduced effect on their aggressiveness on barley.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22961,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,T109,rice blast,monocots,4565,Triticum aestivum (related: bread wheat),N4,,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Disruption of ACE1 alleles of T109 showed reduced effect on their aggressiveness on wheat.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22962,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Br118.2,rice blast,monocots,4565,Triticum aestivum (related: bread wheat),N4,,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Disruption of ACE1 alleles of Br118.2 showed reduced effect on their aggressiveness on wheat.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22963,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,ACE1Ken; ACE1Br48; ACE1Br118.2; ACE1T109,,,,,318829,Magnaporthe oryzae,,PO12-7301-2,rice blast,monocots,4530,Oryza sativa (related: rice),Bala,,,Leaves,secondary metabolite gene cluster,,,,loss of pathogenicity,,,,,no lesion,,,,,no,,,,,,,gene mutation,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,"Transformants carrying ACE1Ken; ACE1Br48, ACE1Br118.2, and ACE1T109 gained complete avirulence on Bala",T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22964,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,ACE1Ken; ACE1Br48; ACE1Br118.2; ACE1T109,,,,,318829,Magnaporthe oryzae,,PO12-7301-2,rice blast,monocots,4530,Oryza sativa (related: rice),Aichi-asahi,,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene mutation,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,"Transformants carrying ACE1Ken; ACE1Br48, ACE1Br118.2, and ACE1T109 showed reduced virulence on Aichi-asahi.",T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22965,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,ACE1Ken; ACE1Br48; ACE1Br118.2; ACE1T109,,,,,318829,Magnaporthe oryzae,,PO12-7301-2,rice blast,monocots,4513,Hordeum vulgare (related: barley),Nigrate,,,Leaves,secondary metabolite gene cluster,,,,increased virulence (hypervirulence),,,,,larger lesions,,,,,no,,,,,,,gene mutation,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,"Transformants carrying ACE1Ken; ACE1Br48, ACE1Br118.2, and ACE1T109 showed strong virulence on nigrate.",T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22966,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,ACE1BrC183A,,,,,318829,Magnaporthe oryzae,,PO12-7301-2,rice blast,monocots,4530,Oryza sativa (related: rice),Bala,,,Leaves,secondary metabolite gene cluster,,,,loss of pathogenicity,,,,,no lesion,,,,,no,,,,,,,gene mutation,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Transformants carrying ACE1BrC183A gained same virulence on Bala as PO12-7301-2,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22967,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,ACE1BrC183A,,,,,318829,Magnaporthe oryzae,,PO12-7301-2,rice blast,monocots,4530,Oryza sativa (related: rice),Aichi-asahi,,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene mutation,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Transformants carrying ACE1BrC183A showed same virulence on Aichi-asahi as s PO12-7301-2.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22968,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,ACE1BrC183A,,,,,318829,Magnaporthe oryzae,,PO12-7301-2,rice blast,monocots,4513,Hordeum vulgare (related: barley),Nigrate,,,Leaves,secondary metabolite gene cluster,,,,increased virulence (hypervirulence),,,,,larger lesions,,,,,no,,,,,,,gene mutation,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Transformants carrying ACE1BrC183A showed same virulence on nigrate as PO12-7301-2.,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22969,PHI:124765,UniProt,G4MVZ2,GenBank,EHA55860,,,70-15,ACE1 (MGG_12447),chromosome 2,ACE1BrC183A,,,,,318829,Magnaporthe oryzae,,Br48,rice blast,monocots,4565,Triticum aestivum (related: bread wheat),Norin 4 (N4),,,Leaves,secondary metabolite gene cluster,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38965407,PubMed,10.1038/s42003-024-06517-7,Commun Biol. 2024 Jul 4;7(1):812.,tosayuki@kobe-u.ac.jp,Transformants carrying ACE1BrC183A showed reduced virulence on N4,T T P Vy 2024,2024,2 genes,Vy-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22970,PHI:124767,UniProt,G4N1T8,GenBank,EHA52453,,,70-15,MoGep4 (XP_003712260.1),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4513,Hordeum vulgare (related: barley),E9,,,Leaves,cardiolipin biosynthesis-related gene,,,cell wall integrity signaling pathway,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,wild type,no,Congo red;calcofluor white (CFW);calcofluor white (CFW),Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38946254,PubMed,10.1111/pce.15021,Plant Cell Environ. 2024 Jul 1.,leeguotian@163.com,"Mutant Mogep4 caused no lesions on detached barley leaves at five days postinoculation (dpi), whereas abundant typical necrotic lesions developed on leaves inoculated with WT, Mocld1, Motaz1, and Mogep4 complementation strains",P Sun 2024,2024,3 genes,Sun-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22971,PHI:124768,UniProt,G4MV50,GenBank,EHA54065,,,70-15,MoCld1 (XP_003713872.1),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4513,Hordeum vulgare (related: barley),E9,,,Leaves,phosphatidyl synthase,,,cell wall integrity signaling pathway,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38946254,PubMed,10.1111/pce.15021,Plant Cell Environ. 2024 Jul 1.,leeguotian@163.com,"Mutant Mogep4 caused no lesions on detached barley leaves at five days postinoculation (dpi), whereas abundant typical necrotic lesions developed on leaves inoculated with WT, Mocld1, Motaz1, and Mogep4 complementation strains",P Sun 2024,2024,3 genes,Sun-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22972,PHI:124769,UniProt,G4MTA6,GenBank,EHA53852,,,70-15,MoTaz1 (XP_003713659.1),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4513,Hordeum vulgare (related: barley),E9,,,Leaves,phosphatidyl synthase,,,cell wall integrity signaling pathway,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,38946254,PubMed,10.1111/pce.15021,Plant Cell Environ. 2024 Jul 1.,leeguotian@163.com,"Mutant Mogep4 caused no lesions on detached barley leaves at five days postinoculation (dpi), whereas abundant typical necrotic lesions developed on leaves inoculated with WT, Mocld1, Motaz1, and Mogep4 complementation strains",P Sun 2024,2024,3 genes,Sun-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22973,PHI:124767,UniProt,G4N1T8,GenBank,EHA52453,,,70-15,MoGep4 (XP_003712260.1),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4530,Oryza sativa (related: rice),Lijiangxintuanheigu (LTH),,,Leaves,cardiolipin biosynthesis-related gene,,,cell wall integrity signaling pathway,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,wild type,no,Congo red;calcofluor white (CFW);calcofluor white (CFW),Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38946254,PubMed,10.1111/pce.15021,Plant Cell Environ. 2024 Jul 1.,leeguotian@163.com,"Mogep4 failed to develop lesions at 6 dpi, whereas the control strains caused abundant typical necrotic blast lesions.",P Sun 2024,2024,3 genes,Sun-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22974,PHI:124767,UniProt,G4N1T8,GenBank,EHA52453,,,70-15,MoGep4 (XP_003712260.1),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4513,Hordeum vulgare (related: barley),E9,,,Leaves,cardiolipin biosynthesis-related gene,,,cell wall integrity signaling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,wild type,no,Congo red;calcofluor white (CFW);calcofluor white (CFW),Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38946254,PubMed,10.1111/pce.15021,Plant Cell Environ. 2024 Jul 1.,leeguotian@163.com,"On wounded rice and barley leaves, the lesion size caused by Mogep4 was much smaller compared to that caused by the WT strain.",P Sun 2024,2024,3 genes,Sun-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22975,PHI:124767,UniProt,G4N1T8,GenBank,EHA52453,,,70-15,MoGep4 (XP_003712260.1),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4530,Oryza sativa (related: rice),Lijiangxintuanheigu (LTH),,,Leaves,cardiolipin biosynthesis-related gene,,,cell wall integrity signaling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,wild type,no,Congo red;calcofluor white (CFW);calcofluor white (CFW),Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,38946254,PubMed,10.1111/pce.15021,Plant Cell Environ. 2024 Jul 1.,leeguotian@163.com,"On wounded rice and barley leaves, the lesion size caused by Mogep4 was much smaller compared to that caused by the WT strain.",P Sun 2024,2024,3 genes,Sun-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22976,PHI:124770,UniProt,A0A0H3U5M6,GenBank,AID59201,,,,PEL1(MW266124),,,,,,,189291,Meloidogyne graminicola,,,rice damage,monocots,4530,Oryza sativa (related: rice),Nipponbare,,,Roots; plant,probable pectate lyase F,,,,unaffected pathogenicity,,,,,,,,,,,,,,,,,altered gene expression / gene regulation: silencing,,,NN,33868351,PubMed,10.3389/fpls.2021.651627,Front Plant Sci. 2021 Mar 22;12:651627.,zhuokan@scau.edu.cn,The transgenic rice lines showed no significant differences compared with the WT plants.,J Chen 2021,2021,1 gene,Chen-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22977,PHI:124771,UniProt,A0A4E9DS39,GenBank,VIO54622,,,,BUD14 (FGSG_04118),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Xiaoyan 22,,,Spikelets,SH3 domain-containing protein,,,,reduced virulence,,,,,typical scab symptoms,reduced,wild type,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33645871,PubMed,10.1111/1462-2920.15446,Environ Microbiol. 2021 Sep;23(9):5052-5068.,wgh2891458@163,"The Fgbud14 deletion mutant was slightly reduced in growth, conidiation and virulence.",J Liang 2021,2021,1 gene,Liang-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22978,PHI:124771,UniProt,A0A4E9DS39,GenBank,VIO54622,,,,BUD14 (FGSG_04118),,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4577,Zea mays (related: maize),Pioneer 2375,,,Corn silks,SH3 domain-containing protein,,,,reduced virulence,,,,,typical scab symptoms,reduced,wild type,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33645871,PubMed,10.1111/1462-2920.15446,Environ Microbiol. 2021 Sep;23(9):5052-5068.,wgh2891458@163,"The Fgbud14 deletion mutant was slightly reduced in growth, conidiation and virulence.",J Liang 2021,2021,1 gene,Liang-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22979,PHI:124772,UniProt,A0A0A2L865,GenBank,KGO75376,,,PHI-1,SntB,,,,,,,40296,Penicillium italicum,,Ku70,green mould,eudicot,2711,Citrus sinensis (related: sweet orange),,,,fruit,epigentic regulator,,,CCR pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,CaCl2;NaCl;ferrous sulfate (FeSO4);copper(II) chloride (CuCl2);KCl;MgSO4;sodium dodecyl sulphate (SDS);Congo red,CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;ferrous sulfate (FeSO4): CHEBI:75832; ;copper(II) chloride (CuCl2): CHEBI:49553; ;KCl: CHEBI:32588; ;MgSO4: CHEBI:32599; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,38921355,PubMed,10.3390/jof10060368,J Fungi (Basel). 2024 May 21;10(6):368.,penglt12@mail.hzau.edu.cn,The diameter of the decay lesion was reduced by 51.1% on the fifth day postinoculation with ΔPiSntB compared with PiKu70 inoculations.,C Li 2024,2024,1 gene,Li-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22980,PHI:124773,UniProt,Q00909,GenBank,AAM48910,,,NRRL 28439,Tri5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Apogee,,,Coleoptiles,trichodiene synthase,,,DON biosynthesis pathway,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,38877764,PubMed,10.1111/mpp.13485,Mol Plant Pathol. 2024 Jun;25(6):e13485.,kim.hammond-kosack@rothamsted. ac.uk,wheat coleoptiles revealed no differences in lesion length between the WT PH-1 strain and single gene deletion mutant ΔTri5.,V J Armer 2024,2024,1 gene,Armer-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22981,PHI:124773,UniProt,Q00909,GenBank,AAM48910,,,NRRL 28439,Tri5,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Apogee,,,spikelets,trichodiene synthase,,,DON biosynthesis pathway,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,38877764,PubMed,10.1111/mpp.13485,Mol Plant Pathol. 2024 Jun;25(6):e13485.,kim.hammond-kosack@rothamsted. ac.uk,wheat spikelets revealed reduced in lesion length between the WT PH-1 strain and single gene deletion mutant ΔTri5.,V J Armer 2024,2024,1 gene,Armer-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22982,PHI:124774,UniProt,W7LYD7,GenBank,EWG44328,,,7600,pex8 (FVEG_05423),chromosome 3,,,Pex13 (FVEG_00529),UniProt: W7LM43; GenBank: EWG36540,,117187,Fusarium verticillioides,334819,7600,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Stalk,DTM peroxins,,,,unaffected pathogenicity,,,,,wild type,reduced,,reduced,,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33749306,PubMed,10.1094/MPMI-10-20-0273-R,Mol Plant Microbe Interact. 2021 Jul;34(7):803-814.,wangzh@fafu.edu.cn,ΔFvPex8 mutant did not exhibit any negative effect on F. verticillioides virulence.,W Yu 2021,2021,4 genes,Yu-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22983,PHI:124775,UniProt,W7LM43,GenBank,EWG36540,,,7600,pex13 (FVEG_00529),chromosome 1,,,,,,117187,Fusarium verticillioides,334819,7600,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Stalk,DTM peroxins,,,,reduced virulence,,,,,less rot symptoms,reduced,,wild type,,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33749306,PubMed,10.1094/MPMI-10-20-0273-R,Mol Plant Microbe Interact. 2021 Jul;34(7):803-814.,wangzh@fafu.edu.cn,ΔFvpex13 mutant showed drastically reduced rot when compared with the WT progenitor and other mutants.,W Yu 2021,2021,4 genes,Yu-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22984,PHI:124776,UniProt,W7M2P5,GenBank,EWG41845,,,7600,pex14 (FVEG_03847),chromosome 2,,,,,,117187,Fusarium verticillioides,334819,7600,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Stalk,DTM peroxins,,,,increased virulence (hypervirulence),,,,,high rot symptoms,reduced,,wild type,,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33749306,PubMed,10.1094/MPMI-10-20-0273-R,Mol Plant Microbe Interact. 2021 Jul;34(7):803-814.,wangzh@fafu.edu.cn,ΔFvpex14 mutant showed high rot when compared with the WT progenitor and other mutants.,W Yu 2021,2021,4 genes,Yu-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22985,PHI:124777,UniProt,W7MXY6,GenBank,EWG52655,,,7600,pex33 (FVEG_11334),chromosome 9,,,,,,117187,Fusarium verticillioides,334819,7600,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Stalk,DTM peroxins,,,,increased virulence (hypervirulence),,,,,high rot symptoms,reduced,,wild type,,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33749306,PubMed,10.1094/MPMI-10-20-0273-R,Mol Plant Microbe Interact. 2021 Jul;34(7):803-814.,wangzh@fafu.edu.cn,ΔFvpex33 mutant showed high rot when compared with the WT progenitor and other mutants.,W Yu 2021,2021,4 genes,Yu-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22986,PHI:124776,UniProt,W7M2P5,GenBank,EWG41845,,,7600,pex14 (FVEG_03847),chromosome 2,,,,,PHI:124777,117187,Fusarium verticillioides,334819,7600,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Stalk,DTM peroxins,,,,reduced virulence,,,,,less rot symptoms,reduced,,reduced,,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33749306,PubMed,10.1094/MPMI-10-20-0273-R,Mol Plant Microbe Interact. 2021 Jul;34(7):803-814.,wangzh@fafu.edu.cn,ΔFvpex14 mutant showed high rot when compared with the WT progenitor and other mutants.,W Yu 2021,2021,4 genes,Yu-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22987,PHI:124777,UniProt,W7MXY6,GenBank,EWG52655,,,7600,pex33 (FVEG_11334),chromosome 9,,,,,PHI:124776,117187,Fusarium verticillioides,334819,7600,maize ear rot,monocots,4577,Zea mays (related: maize),B73,,,Stalk,DTM peroxins,,,,reduced virulence,,,,,less rot symptoms,reduced,,reduced,,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33749306,PubMed,10.1094/MPMI-10-20-0273-R,Mol Plant Microbe Interact. 2021 Jul;34(7):803-814.,wangzh@fafu.edu.cn,ΔFvpex33/14 mutant showed drastically reduced rot when compared with the WT progenitor and other mutants.,W Yu 2021,2021,4 genes,Yu-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22988,PHI:124778,UniProt,A0A0H2XAD1,GenBank,AAY49651,,,8004,XopE2 (XC_2602),,,,,,,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,SA signaling pathway,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Deletion of XopE2Xcc or XopLXcc does not significantly affect Xcc 8004 pathogenicity in Arabidopsis.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22989,PHI:124779,UniProt,A0A0H2XEN0,GenBank,AAY51309,,,8004,XopL (XC_4273),,,,,,,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,SA signaling pathway,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Deletion of XopE2Xcc or XopLXcc does not significantly affect Xcc 8004 pathogenicity in Arabidopsis.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22990,PHI:124780,UniProt,A0A0H2X2D1,GenBank,AAY47144,,,8004,XC0052,,,,,,PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22991,PHI:124781,UniProt,A0A0H2X2M3,GenBank,AAY47328,,,8004,XC0241,,,,,,PHI:124780; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22992,PHI:124782,UniProt,A0A0H2X3L9,GenBank,AAY47622,,,8004,XC0541,,,,,,PHI:124780; PHI:124781; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22993,PHI:124783,UniProt,A0A0H2X521,GenBank,AAY47623,,,8004,XC0542,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22994,PHI:124784,UniProt,A0A0H2X6U6,GenBank,AAY48279,,,8004,XC1210,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22995,PHI:124785,UniProt,Q4UWF4,GenBank,AFP74845,,,8004,XC1553,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22996,PHI:124786,UniProt,A0A0H2X8X1,GenBank,AAY49067,,,8004,XC2004,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22997,PHI:124787,UniProt,A0A0H2X7E0,GenBank,AAY49138,,,8004,XC2081,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22998,PHI:124788,UniProt,A0A0H2X9B8,GenBank,AAY49265,,,8004,XC2210,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 22999,PHI:124789,UniProt,A0A0H2XAD1,GenBank,AAY49651,,,8004,XC2602,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23000,PHI:124790,UniProt,A0A0H2XB85,GenBank,AAY50042,,,8004,XC2994,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23001,PHI:124791,UniProt,A0A0H2X9N7,GenBank,AAY50043,,,8004,XC2995,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23002,PHI:124792,UniProt,A0A0H2XBQ0,GenBank,AAY50204,,,8004,XC3160,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23003,PHI:124793,UniProt,A0A0H2X9U1,GenBank,AAY50220,,,8004,XC3176,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23004,PHI:124794,UniProt,A0A0H2XA81,GenBank,AAY50221,,,8004,XC3177,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23005,PHI:124795,UniProt,A0A0H2XDD4,GenBank,AAY50842,,,8004,XC3802,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23006,PHI:124796,UniProt,A0A0H2XEN0,GenBank,AAY51309,,,8004,XC4273,,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,Δ17E caused slight yellowing around the inoculation site.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23007,PHI:124778,UniProt,A0A0H2XAD1,GenBank,AAY49651,,,8004,XopE2 (XC_2602),,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,SA signaling pathway,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23008,PHI:124780,UniProt,A0A0H2X2D1,GenBank,AAY47144,,,8004,XC0052,,,,,,PHI:124778; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23009,PHI:124781,UniProt,A0A0H2X2M3,GenBank,AAY47328,,,8004,XC0241,,,,,,PHI:124778; PHI:124780; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23010,PHI:124782,UniProt,A0A0H2X3L9,GenBank,AAY47622,,,8004,XC0541,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23011,PHI:124783,UniProt,A0A0H2X521,GenBank,AAY47623,,,8004,XC0542,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23012,PHI:124784,UniProt,A0A0H2X6U6,GenBank,AAY48279,,,8004,XC1210,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23013,PHI:124785,UniProt,Q4UWF4,GenBank,AFP74845,,,8004,XC1553,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23014,PHI:124786,UniProt,A0A0H2X8X1,GenBank,AAY49067,,,8004,XC2004,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23015,PHI:124787,UniProt,A0A0H2X7E0,GenBank,AAY49138,,,8004,XC2081,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23016,PHI:124788,UniProt,A0A0H2X9B8,GenBank,AAY49265,,,8004,XC2210,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23017,PHI:124789,UniProt,A0A0H2XAD1,GenBank,AAY49651,,,8004,XC2602,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23018,PHI:124790,UniProt,A0A0H2XB85,GenBank,AAY50042,,,8004,XC2994,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23019,PHI:124791,UniProt,A0A0H2X9N7,GenBank,AAY50043,,,8004,XC2995,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23020,PHI:124792,UniProt,A0A0H2XBQ0,GenBank,AAY50204,,,8004,XC3160,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23021,PHI:124793,UniProt,A0A0H2X9U1,GenBank,AAY50220,,,8004,XC3176,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23022,PHI:124794,UniProt,A0A0H2XA81,GenBank,AAY50221,,,8004,XC3177,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23023,PHI:124795,UniProt,A0A0H2XDD4,GenBank,AAY50842,,,8004,XC3802,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23024,PHI:124796,UniProt,A0A0H2XEN0,GenBank,AAY51309,,,8004,XC4273,,,,,,PHI:124778; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,mild disease,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,"Δ17E(xopE2Xcc) exhibited significantly milder disease symptoms and low bacterial proliferation, indicating that XopE2Xcc expression conferred resistance to Xcc 8004 infection in Arabidopsis.",J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23025,PHI:124779,UniProt,A0A0H2XEN0,GenBank,AAY51309,,,8004,XopL (XC_4273),,,,,,PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,SA signaling pathway,effector (plant avirulence determinant),,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23026,PHI:124780,UniProt,A0A0H2X2D1,GenBank,AAY47144,,,8004,XC0052,,,,,,PHI:124779; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23027,PHI:124781,UniProt,A0A0H2X2M3,GenBank,AAY47328,,,8004,XC0241,,,,,,PHI:124779; PHI:124780; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23028,PHI:124782,UniProt,A0A0H2X3L9,GenBank,AAY47622,,,8004,XC0541,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23029,PHI:124783,UniProt,A0A0H2X521,GenBank,AAY47623,,,8004,XC0542,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23030,PHI:124784,UniProt,A0A0H2X6U6,GenBank,AAY48279,,,8004,XC1210,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23031,PHI:124785,UniProt,Q4UWF4,GenBank,AFP74845,,,8004,XC1553,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23032,PHI:124786,UniProt,A0A0H2X8X1,GenBank,AAY49067,,,8004,XC2004,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23033,PHI:124787,UniProt,A0A0H2X7E0,GenBank,AAY49138,,,8004,XC2081,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23034,PHI:124788,UniProt,A0A0H2X9B8,GenBank,AAY49265,,,8004,XC2210,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23035,PHI:124789,UniProt,A0A0H2XAD1,GenBank,AAY49651,,,8004,XC2602,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23036,PHI:124790,UniProt,A0A0H2XB85,GenBank,AAY50042,,,8004,XC2994,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23037,PHI:124791,UniProt,A0A0H2X9N7,GenBank,AAY50043,,,8004,XC2995,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124792; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23038,PHI:124792,UniProt,A0A0H2XBQ0,GenBank,AAY50204,,,8004,XC3160,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124793; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23039,PHI:124793,UniProt,A0A0H2X9U1,GenBank,AAY50220,,,8004,XC3176,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124794; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23040,PHI:124794,UniProt,A0A0H2XA81,GenBank,AAY50221,,,8004,XC3177,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124795; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23041,PHI:124795,UniProt,A0A0H2XDD4,GenBank,AAY50842,,,8004,XC3802,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124796,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23042,PHI:124796,UniProt,A0A0H2XEN0,GenBank,AAY51309,,,8004,XC4273,,,,,,PHI:124779; PHI:124780; PHI:124781; PHI:124782; PHI:124783; PHI:124784; PHI:124785; PHI:124786; PHI:124787; PHI:124788; PHI:124789; PHI:124790; PHI:124791; PHI:124792; PHI:124793; PHI:124794; PHI:124795,339,Xanthomonas campestris,314565,"pv. Campestris, strain 8004",black rot disease,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,38921746,PubMed,10.3390/pathogens13060448,Pathogens. 2024 May 24;13(6):448.,yqhe_gxu@163.com,The disease symptoms of Δ17E(xopLXcc) were significantly higher than those of Δ17E and ΔhrcV in Arabidopsis plants but lower than those of Xcc 8004.,J Huang 2024,2024,19 genes,Huang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23043,PHI:124797,UniProt,A0A7J6IPU7,GenBank,KAF4477736,,,Nara gc5,Atg4,,,,CfAtg8 (KAF4481970.1),UniProt: A0A7J6J0X0; GenBank: KAF4481970,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,Leaves,cysteine protease,,,,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full ; gene complementation,,,NN,38921417,PubMed,10.3390/jof10060431,J Fungi (Basel). 2024 Jun 18;10(6):431.,csufzsp@163.com,ΔCfatg4 mutant did not produce any lesion on leaves compared to WT.,S Guo 2024,2024,2 genes,Guo-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23044,PHI:124797,UniProt,A0A7J6IPU7,GenBank,KAF4477736,,,Nara gc5,Atg4,,,,CfAtg8 (KAF4481970.1),UniProt: A0A7J6J0X0; GenBank: KAF4481970,PHI:124798,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,Leaves,cysteine protease,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene mutation,,,NN,38921417,PubMed,10.3390/jof10060431,J Fungi (Basel). 2024 Jun 18;10(6):431.,csufzsp@163.com,ΔCfatg4/CfAtg81–160 strain restores the pathogenicity of the ΔCfatg4 mutant but could not conduct this to the same level as WT and ΔCfatg4/CfATG4 strains.,S Guo 2024,2024,2 genes,Guo-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23045,PHI:124798,UniProt,A0A7J6J0X0,GenBank,KAF4481970,,,Nara gc5,Atg8 (KAF4481970.1),,GFP-CfAtg81–160,,,,PHI:124797,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,385388,Camellia oleifera (related: tea-oil plant),,,,Leaves,cysteine protease,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene mutation,,,NN,38921417,PubMed,10.3390/jof10060431,J Fungi (Basel). 2024 Jun 18;10(6):431.,csufzsp@163.com,ΔCfatg4/CfAtg81–160 strain restores the pathogenicity of the ΔCfatg4 mutant but could not conduct this to the same level as WT and ΔCfatg4/CfATG4 strains.,S Guo 2024,2024,2 genes,Guo-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23046,PHI:124797,UniProt,A0A7J6IPU7,GenBank,KAF4477736,,,Nara gc5,Atg4,,,,CfAtg8 (KAF4481970.1),UniProt: A0A7J6J0X0; GenBank: KAF4481970,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,cysteine protease,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full ; gene complementation,,,NN,38921417,PubMed,10.3390/jof10060431,J Fungi (Basel). 2024 Jun 18;10(6):431.,csufzsp@163.com,ΔCfatg4 mutant produce reduce lesion on leaves compared to WT.,S Guo 2024,2024,2 genes,Guo-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23047,PHI:124797,UniProt,A0A7J6IPU7,GenBank,KAF4477736,,,Nara gc5,Atg4,,,,CfAtg8 (KAF4481970.1),UniProt: A0A7J6J0X0; GenBank: KAF4481970,PHI:124798,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,cysteine protease,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene mutation,,,NN,38921417,PubMed,10.3390/jof10060431,J Fungi (Basel). 2024 Jun 18;10(6):431.,csufzsp@163.com,"ΔCfatg4/CfAtg81–160 strain was inoculated on apples and showed significantly increased lesion areas compared to the ΔCfatg4 strain, and it was also unable to recover to the level of the WT strain.",S Guo 2024,2024,2 genes,Guo-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23048,PHI:124798,UniProt,A0A7J6J0X0,GenBank,KAF4481970,,,Nara gc5,Atg8 (KAF4481970.1),,GFP-CfAtg81–160,,,,PHI:124797,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicots,3750,Malus domestica (related: apple),,,,fruit,cysteine protease,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,NaCl;KCl;sodium dodecyl sulphate (SDS);dithiothreitol (DTT),NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene mutation,,,NN,38921417,PubMed,10.3390/jof10060431,J Fungi (Basel). 2024 Jun 18;10(6):431.,csufzsp@163.com,"ΔCfatg4/CfAtg81–160 strain was inoculated on apples and showed significantly increased lesion areas compared to the ΔCfatg4 strain, and it was also unable to recover to the level of the WT strain.",S Guo 2024,2024,2 genes,Guo-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23049,PHI:124799,UniProt,K3V578,GenBank,EKJ68287,,,CS3096,VelB (XP_009262923.1),,,,,,,101028,Fusarium pseudograminearum,,2035,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Shixin 828,,,stem; wheat head,velvet family protein,,,metabolic pathway,reduced virulence,,,,,low disease severity,increased,,reduced ; defective,,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38891082,PubMed,10.3390/cells13110950,Cells. 2024 May 30;13(11):950.,konglingxiao163@163.com,The FpVelB mutant strains led to a significantly reduced DI at the stem base and head compared to that caused by the wild-type strain.,Y Wu 2024,2024,2 genes,Wu-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23050,PHI:124800,UniProt,K3VX64,GenBank,EKJ68355,,,CS3096,PKS11,,,,,,,101028,Fusarium pseudograminearum,,2035,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Shixin 828,,,stem; wheat head,synthase gene,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,38891082,PubMed,10.3390/cells13110950,Cells. 2024 May 30;13(11):950.,konglingxiao163@163.com,The phenotypic outcomes indicated that knockout of the synthesis gene had no discernible effect on the growth of the pathogen but led to a reduction in pathogenicity.,Y Wu 2024,2024,2 genes,Wu-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23051,PHI:124801,UniProt,A0A5M9JKW7,GenBank,KAA8570148,,,Mfrc123,Cat2 (KAA8570148.1),,,,,,,38448,Monilinia fructicola,,,blossom blight and fruit rot,eudicot,3760,Prunus persica (related: peach),,,,fruit,catalase,,,,reduced virulence,,,,,smaller lesions,,,reduced,reduced,no,NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,38973095,PubMed,10.1111/mpp.13484,Mol Plant Pathol. 2024 Jul;25(7):e13484.,nikemgh@swu.edu. cn,MfCat2 knockout strain (ΔMfCat2) showed reduced pathogenicity and sensitivity to JCP1-7 and eucalyptol,S Chen 2024,2024,1 gene,Chen-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23052,PHI:124802,UniProt,A0A384JU47,GenBank,ATZ54116,,,B05.10,sdr2 (Bcin10g01350),chromosome BCIN10,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,fruit,membrane protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,hydrogen peroxide (H2O2);KCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38940906,PubMed,10.1007/s00253-024-13238-8,Appl Microbiol Biotechnol. 2024 Jun 28;108(1):398.,shiliming@caas.cn,"Targeted deletion of Bcsdr2 blocked several phenotypic defects in aspects of mycelial growth, conidiation and virulence.",W Zhang 2024,2024,1 gene,Zhang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23053,PHI:124802,UniProt,A0A384JU47,GenBank,ATZ54116,,,B05.10,sdr2 (Bcin10g01350),chromosome BCIN10,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3747,Fragaria x ananassa (related: strawberry),,,,Leaves,membrane protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,hydrogen peroxide (H2O2);KCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38940906,PubMed,10.1007/s00253-024-13238-8,Appl Microbiol Biotechnol. 2024 Jun 28;108(1):398.,shiliming@caas.cn,"Targeted deletion of Bcsdr2 blocked several phenotypic defects in aspects of mycelial growth, conidiation and virulence.",W Zhang 2024,2024,1 gene,Zhang-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23054,PHI:124803,UniProt,A0A0M3Q8U4,GenBank,ALC04451,,,,Scr82 (KT215396),,,,,,,4784,Phytophthora capsici,,Pc537,"crown infections, leaf spot, and foliar blight",eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33819070,PubMed,10.1094/MPMI-01-21-0025-R,Mol Plant Microbe Interact. 2021 Aug;34(8):891-903.,xrchen@yzu.edu.cn,Virulence tests showed that the mutants caused lesions significantly smaller than those of the Ctrl on both N. benthamiana leaves.,Z H Zhang 2021,2021,1 gene,Zhang-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23055,PHI:124803,UniProt,A0A0M3Q8U4,GenBank,ALC04451,,,,Scr82 (KT215396),,,,,,,4784,Phytophthora capsici,,Pc537,"crown infections, leaf spot, and foliar blight",eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,larger lesions,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,33819070,PubMed,10.1094/MPMI-01-21-0025-R,Mol Plant Microbe Interact. 2021 Aug;34(8):891-903.,xrchen@yzu.edu.cn,The overexpression strains showed increased virulence compared with the WT.,Z H Zhang 2021,2021,1 gene,Zhang-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23056,PHI:124803,UniProt,A0A0M3Q8U4,GenBank,ALC04451,,,,Scr82 (KT215396),,,,,,,4784,Phytophthora capsici,,Pc537,"crown infections, leaf spot, and foliar blight",eudicots,4072,Capsicum annuum (no common name found),grossum,,,Stems,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33819070,PubMed,10.1094/MPMI-01-21-0025-R,Mol Plant Microbe Interact. 2021 Aug;34(8):891-903.,xrchen@yzu.edu.cn,Virulence tests showed that the mutants caused lesions significantly smaller than those of the Ctrl on both bell pepper stems.,Z H Zhang 2021,2021,1 gene,Zhang-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23057,PHI:124803,UniProt,A0A0M3Q8U4,GenBank,ALC04451,,,,Scr82 (KT215396),,,,,,,4784,Phytophthora capsici,,Pc537,"crown infections, leaf spot, and foliar blight",eudicots,4072,Capsicum annuum (no common name found),grossum,,,Stems,effector protein,,,,effector (plant avirulence determinant),,,,,larger lesions,,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,33819070,PubMed,10.1094/MPMI-01-21-0025-R,Mol Plant Microbe Interact. 2021 Aug;34(8):891-903.,xrchen@yzu.edu.cn,The overexpression strains showed increased virulence compared with the WT.,Z H Zhang 2021,2021,1 gene,Zhang-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23058,PHI:124804,UniProt,A0A345CXM3,GenBank,AXF78190,,,MDcuke,Eps,,,,,,,65700,Erwinia tracheiphila,,BHKY,bacterial wilt,eudicots,3663,Curcubita pepo (related: zucchini),Yellow Crookneck,,,Seedling,exopolysaccharide synthase,,,,loss of pathogenicity,,,,,no symptoms,,,reduced,,,,,,,,,gene deletion: full,,,NN,38979168,PubMed,10.1101/2024.06.24.600446,bioRxiv [Preprint]. 2024 Jun 25:2024.06.24.600446.,,"By 21 DPI, 9 out of 12 plants inoculated with WT had died where no wilting symptoms or death were observed for plants inoculated with the mutant strain.",J Rocha 2024,2024,1 gene,Rocha-2024,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23059,PHI:124805,UniProt,A0A8A0XVJ6,GenBank,QSQ85777,,,Z7,ACTR (MW311077),,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicots,85571,Citrus reticulata (related: tangerine),Blanco,,,Leaves,transcription regulator,,,ACT toxin biosynthesis pathway,reduced virulence,,,yes,,smaller necrotic lesions,,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);CaCl2;NaCl;CuSO4;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;CuSO4: CHEBI:23414; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,33740671,PubMed,10.1016/j.micres.2021.126747,Microbiol Res. 2021 Jul;248:126747.,hyli@zju.edu.cn,ACTR mutants displayed a significant loss of ACT toxin production and a decreased virulence on citrus leaves and there was no affect on vegetative growth and sporulation.,L Li 2021,2021,1 gene,33740671_Li-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23060,PHI:124805,UniProt,A0A8A0XVJ6,GenBank,QSQ85777,,,Z7,ACTR (MW311077),,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicots,85571,Citrus reticulata (related: tangerine),Blanco,,,Leaves,transcription regulator,,,ACT toxin biosynthesis pathway,reduced virulence,,,yes,,smaller necrotic lesions,,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);CaCl2;NaCl;CuSO4;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;CuSO4: CHEBI:23414; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,altered gene expression / gene regulation: silencing,,,NN,33740671,PubMed,10.1016/j.micres.2021.126747,Microbiol Res. 2021 Jul;248:126747.,hyli@zju.edu.cn,ACTR mutants displayed a significant loss of ACT toxin production and a decreased virulence on citrus leaves and there was no affect on vegetative growth and sporulation.,L Li 2021,2021,1 gene,33740671_Li-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23061,PHI:124806,UniProt,G4N3U9,GenBank,EHA52722,,,70-15,cda7 (MGG_05023),chromosome 3,,,,,,318829,Pyricularia oryzae,1271791,KJ201,rice blast,monocots,4530,Oryza sativa (related: rice),Xiushui 134,,,Leaves,chitin deacetylase,,,,reduced virulence,,,yes,,smaller lesions,wild type,,wild type,wild type,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33744788,PubMed,10.1016/j.micres.2021.126749,Microbiol Res. 2021 Jul;248:126749.,xhliu@zju.edu.cn,"Knockout mutant of ΔPocda7 had no significant effect on fungal morphogenic development, including conidiation, germination but virulence was significantly reduced in host plants.",M D Dai 2021,2021,1 gene,33744788_Dai-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23062,PHI:124807,UniProt,L2FWZ2,GenBank,ELA30263,,,Nara gc5,Ste50,chromosome unknown,,,,,,474922,Colletotrichum gloeosporioides,,CFCC80308,fruit rot,eudicots,1217306,Populus x beijingensis (no common name found),,,,Leaves,mitogen-activated protein kinase,,,MAPK pathway,loss of pathogenicity,,,yes,,no lesion,,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,33752111,PubMed,10.1016/j.micres.2021.126748,Microbiol Res. 2021 Jul;248:126748.,chengmt@bjfu.edu.cn,"Mutants of CgSte50, CgSte11, CgSte7 showed complete loss of virulence on intact and wounded leaves compared to WT and all complementation.",X Wang 2021,2021,3 genes,33752111_Wang-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23063,PHI:124808,UniProt,L2G9S2,GenBank,ELA35384,,,Nara gc5,Ste11,chromosome unknown,,,,,,474922,Colletotrichum gloeosporioides,,CFCC80308,fruit rot,eudicots,1217306,Populus x beijingensis (no common name found),,,,Leaves,mitogen-activated protein kinase,,,MAPK pathway,loss of pathogenicity,,,yes,,no lesion,,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,33752111,PubMed,10.1016/j.micres.2021.126748,Microbiol Res. 2021 Jul;248:126748.,chengmt@bjfu.edu.cn,"Mutants of CgSte50, CgSte11, CgSte7 showed complete loss of virulence on intact and wounded leaves compared to WT and all complementation.",X Wang 2021,2021,3 genes,33752111_Wang-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23064,PHI:124809,UniProt,L2FV46,GenBank,ELA30304,,,Nara gc5,Ste7,chromosome unknown,,,,,,474922,Colletotrichum gloeosporioides,,CFCC80308,fruit rot,eudicots,1217306,Populus x beijingensis (no common name found),,,,Leaves,mitogen-activated protein kinase,,,MAPK pathway,loss of pathogenicity,,,yes,,no lesion,,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,33752111,PubMed,10.1016/j.micres.2021.126748,Microbiol Res. 2021 Jul;248:126748.,chengmt@bjfu.edu.cn,"Mutants of CgSte50, CgSte11, CgSte7 showed complete loss of virulence on intact and wounded leaves compared to WT and all complementation.",X Wang 2021,2021,3 genes,33752111_Wang-2021,BATCH_135,2024-07-01,MC,,,,,,,,,,,,,
,,Record 23065,PHI:124810,UniProt,A0A0H2XCB3,GenBank,AAY50530,,,8004,amyA (XC3487),,,,,,,339,Xanthomonas campestris,314565,pv.campestris 8004,black rot disease,eudicots,3726,Raphanus sativus (related: radish),,,,Leaves,amylase,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33245253,PubMed,10.1094/PHYTO-08-20-0372-R,Phytopathology. 2021 Jul;111(7):1104-1113.,"tangdj@gxu.edu.cn,",The mean lesion length caused by ΔamyA mutant was significantly shorter than that of wild type strain.,Y Lin 2021,2021,1 gene,Lin-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23066,PHI:124811,UniProt,A0A2H3GW15,GenBank,CAG1982832,,,MDC_Fg202,GPI,,,β2 Tubulin,Uniprot: Q4HZS8; Genbank: ESU16129,,,5518,Fusarium graminearum,,2021,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Huaimai 33,,,Wheat head,glucose-6-phosphate isomerase,,,glycolysis pathway,loss of pathogenicity,,,,,no lesion,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710,,,,,gene deletion: full ; gene complementation,,,NN,33544003,PubMed,10.1094/PHYTO-07-20-0279-R,Phytopathology. 2021 Mar;111(3):531-540.,mgzhou@njau.edu.cn,"ΔFgGPI inhibited hyphal growth, conidial germination and showed no FHB symptoms.",Z Zhou 2021,2021,1 gene,Zhou-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23067,PHI:124811,UniProt,A0A2H3GW15,GenBank,CAG1982832,,,MDC_Fg202,GPI,,,β2 Tubulin,Uniprot: Q4HZS8; Genbank: ESU16129,,,5518,Fusarium graminearum,,2021,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Huaimai 33,,,Coleoptiles,glucose-6-phosphate isomerase,,,glycolysis pathway,reduced virulence,,,,,less symptoms,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710,,,,,gene deletion: full ; gene complementation,,,NN,33544003,PubMed,10.1094/PHYTO-07-20-0279-R,Phytopathology. 2021 Mar;111(3):531-540.,mgzhou@njau.edu.cn,"ΔFgGPI inhibited hyphal growth, conidial germination and showed reduced FHB symptoms.",Z Zhou 2021,2021,1 gene,Zhou-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23068,PHI:124812,UniProt,J4W6X9,GenBank,EJP66050,,,ARSEF 2860,Sid A (BBA_05021),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF2860,white muscardine disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,Larvae,siderophore,,,siderophore biosynthesis pathway,reduced virulence,,,,,,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;bathophenanthroline disulfonic acid (BPS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;bathophenanthroline disulfonic acid (BPS): CHEBI:78159; ;Congo red: CHEBI:34653,,,,,gene disruption ; gene complementation,,,NN,39109629,PubMed,10.1021/acs.jafc.4c02957,J Agric Food Chem. 2024 Aug 21;72(33):18455-18464.,yingsh@zju.edu.cn,Δ BbsidA exhibited a significant decrease in survival percentage compared to wild type and complementary strain.,T F Sun 2024,2024,7 genes,Sun-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23069,PHI:124813,UniProt,J4KNP2,GenBank,EJP66049,,,ARSEF 2860,Sid C (BBA_05020),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF2860,white muscardine disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,Larvae,siderophore,,,siderophore biosynthesis pathway,reduced virulence,,,,,,reduced,,wild type,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;bathophenanthroline disulfonic acid (BPS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;bathophenanthroline disulfonic acid (BPS): CHEBI:78159; ;Congo red: CHEBI:34653,,,,,gene disruption,,,NN,39109629,PubMed,10.1021/acs.jafc.4c02957,J Agric Food Chem. 2024 Aug 21;72(33):18455-18464.,yingsh@zju.edu.cn,Δ BbsidC exhibited a significant decrease in survival percentage compared to wild type and complementary strain.,T F Sun 2024,2024,7 genes,Sun-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23070,PHI:124814,UniProt,J4UJF5,GenBank,EJP63992,,,ARSEF 2860,Sid D (BBA_06997),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF2860,white muscardine disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,Larvae,siderophore,,,siderophore biosynthesis pathway,reduced virulence,,,,,,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;bathophenanthroline disulfonic acid (BPS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;bathophenanthroline disulfonic acid (BPS): CHEBI:78159; ;Congo red: CHEBI:34653,,,,,gene disruption,,,NN,39109629,PubMed,10.1021/acs.jafc.4c02957,J Agric Food Chem. 2024 Aug 21;72(33):18455-18464.,yingsh@zju.edu.cn,Δ BbsidD exhibited a significant decrease in survival percentage compared to wild type and complementary strain.,T F Sun 2024,2024,7 genes,Sun-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23071,PHI:124815,UniProt,J4W0D1,GenBank,EJP63990,,,ARSEF 2860,Sid F (BBA_06995),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF2860,white muscardine disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,Larvae,siderophore,,,siderophore biosynthesis pathway,reduced virulence,,,,,,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;bathophenanthroline disulfonic acid (BPS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;bathophenanthroline disulfonic acid (BPS): CHEBI:78159; ;Congo red: CHEBI:34653,,,,,gene disruption ; gene complementation,,,NN,39109629,PubMed,10.1021/acs.jafc.4c02957,J Agric Food Chem. 2024 Aug 21;72(33):18455-18464.,yingsh@zju.edu.cn,Δ BbsidF exhibited a significant decrease in survival percentage compared to wild type and complementary strain.,T F Sun 2024,2024,7 genes,Sun-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23072,PHI:124816,UniProt,J4KLY0,GenBank,EJP62989,,,ARSEF 2860,Sid H (BBA_08000),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF2860,white muscardine disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,Larvae,siderophore,,,siderophore biosynthesis pathway,unaffected pathogenicity,,,,,,wild type,,wild type,wild type,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;bathophenanthroline disulfonic acid (BPS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;bathophenanthroline disulfonic acid (BPS): CHEBI:78159; ;Congo red: CHEBI:34653,,,,,gene disruption ; gene complementation,,,NN,39109629,PubMed,10.1021/acs.jafc.4c02957,J Agric Food Chem. 2024 Aug 21;72(33):18455-18464.,yingsh@zju.edu.cn,Δ BbsidH exhibited no significant deffernce in survival percentage compared to wild type and complementary strain.,T F Sun 2024,2024,7 genes,Sun-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23073,PHI:124817,UniProt,J5JLF2,GenBank,EJP63991,,,ARSEF 2860,Sid I (BBA_06996),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF2860,white muscardine disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,Larvae,siderophore,,,siderophore biosynthesis pathway,reduced virulence,,,,,,wild type,,wild type,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;bathophenanthroline disulfonic acid (BPS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;bathophenanthroline disulfonic acid (BPS): CHEBI:78159; ;Congo red: CHEBI:34653,,,,,gene disruption ; gene complementation,,,NN,39109629,PubMed,10.1021/acs.jafc.4c02957,J Agric Food Chem. 2024 Aug 21;72(33):18455-18464.,yingsh@zju.edu.cn,Δ BbsidI exhibited a significant decrease in survival percentage compared to wild type and complementary strain.,T F Sun 2024,2024,7 genes,Sun-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23074,PHI:124818,UniProt,J4VSL0,GenBank,EJP61580,,,ARSEF 2860,Sid L (BBA_09490),chromosome unknown,,,,,,176275,Beauveria bassiana,655819,ARSEF2860,white muscardine disease,moths,7137,Galleria mellonella (related: greater wax moth),,,,Larvae,siderophore,,,siderophore biosynthesis pathway,reduced virulence,,,,,,reduced,,wild type,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;menadione;bathophenanthroline disulfonic acid (BPS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;bathophenanthroline disulfonic acid (BPS): CHEBI:78159; ;Congo red: CHEBI:34653,,,,,gene disruption ; gene complementation,,,NN,39109629,PubMed,10.1021/acs.jafc.4c02957,J Agric Food Chem. 2024 Aug 21;72(33):18455-18464.,yingsh@zju.edu.cn,Δ BbsidL exhibited a significant decrease in survival percentage compared to wild type and complementary strain.,T F Sun 2024,2024,7 genes,Sun-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23075,PHI:124819,UniProt,Q4IQX3,GenBank,ESU05562,,,PH-1; NRRL 31084,Nhp6 (XP_011316047.1),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1 (NRRL 31084),Fusarium head blight,monocot,4564,Triticum (related: wheat),Jimai22,,,Wheat heads; Coleoptiles,non-histone protein,,,sterol biosynthesis and aurofusarin biosynthesis,reduced virulence,,,,,lower infection rate,reduced,reduced,reduced ; defective,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39057819,PubMed,10.3390/pathogens13070592,Pathogens. 2024 Jul 16;13(7):592.,zhaoyx@qau.edu.cn,The ΔFgNhp6 mutant exhibited a markedly reduced pathogenicity on wheat coleoptiles and spikes.,J Cao 2024,2024,1 gene,Cao-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23076,PHI:124820,UniProt,A0A4U9F173,GenBank,CAG2006023,,,MDC_Fg202,RUD3 (FGSG_ 04393),,,,RUD3,UniProt: A0A4U9F173; GenBank: CAG2006023,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Jimai 22,,,Wheat head; Coleoptiles,golgin protein,,,ER-to-golgi pathway,reduced virulence,,,,,less symptoms,increased,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,33452023,PubMed,10.1128/AEM.02522-20,Appl Environ Microbiol. 2021 Feb 26;87(6):e02522-20,chenlei@sdau.edu.cn,"Wheat heads and coleoptiles inoculated with the Δrud3 mutant showed only mild symptoms, with an average disease index of <4 compared to wild type and complementary strain.",C Wang 2021,2021,1 gene,Wang-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23077,PHI:124820,UniProt,A0A4U9F173,GenBank,CAG2006023,,,MDC_Fg202,RUD3 (FGSG_ 04393),,"RUD3DCC-GFP, RUD3DGA2-GFP, RUD3DGRAB-GFP",,RUD3,UniProt: A0A4U9F173; GenBank: CAG2006023,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Jimai 22,,,Wheat head; Coleoptiles,golgin protein,,,ER-to-golgi pathway,reduced virulence,,,,,less symptoms,,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,33452023,PubMed,10.1128/AEM.02522-20,Appl Environ Microbiol. 2021 Feb 26;87(6):e02522-20,chenlei@sdau.edu.cn,"Wheat heads inoculated with the Δrud3 domains mutant showed only mild symptoms, with an average disease index compared to wild type.",C Wang 2021,2021,1 gene,Wang-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23078,PHI:124820,UniProt,A0A4U9F173,GenBank,CAG2006023,,,MDC_Fg202,RUD3 (FGSG_ 04393),,RUD3DGA1-GFP,,RUD3,UniProt: A0A4U9F173; GenBank: CAG2006023,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Jimai 22,,,Wheat head; Coleoptiles,golgin protein,,,ER-to-golgi pathway,increased virulence (hypervirulence),,,,,severe symptoms,,,increased,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,33452023,PubMed,10.1128/AEM.02522-20,Appl Environ Microbiol. 2021 Feb 26;87(6):e02522-20,chenlei@sdau.edu.cn,Wheat heads inoculated with the Δrud3 domain mutant showed higher symptoms compared to wild type.,C Wang 2021,2021,1 gene,Wang-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23079,PHI:124821,UniProt,C6XGF0,GenBank,ACT57453,,,psy62,m4405 (CLIBASIA_04405),,m4405 with DC30001hopQ1-1,,,,,34021,Candidatus Liberibacter asiaticus,,,huanglongbing,eudicot,4100,Nicotiana benthamiana (no common name found),,,,Leaves,Sec-dependent secretory protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,functional test in host: transient expression,,,NN,33329478,PubMed,10.3389/fmicb.2020.594669,Front Microbiol. 2020 Nov 30;11:594669.,wangxuefeng@cric.cn,Transgenic N. benthamiana-expressing m4405 with Pseudomonas syringae DC30001hopQ1-1 demonstrated the greatly reduced bacterial proliferation.,C Zhang 2020,2020,1 gene,Zhang-2020,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23080,PHI:124822,UniProt,Q87F38,GenBank,AAO27999,,,Temecula1,copA (PD0100),,,,,,,2371,Xylella fastidiosa,,TemeculaL,Pierce disease of grapes and Citrus variegated chlorosis (cvc),eudicot,4100,Nicotiana benthamiana (no common name found),Petite Havana SR1,,,Leaves,copper homeostasis genes,,,,reduced virulence,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,33554639,PubMed,10.1094/PHYTO-12-20-0531-R,Phytopathology. 2021 Sep;111(9):1520-1529.,lzd0005@auburn.edu,copA mutant showed less symptoms compared to wild type under both water and CuSO4 treatment.,Q Ge 2021,2021,2 genes,Ge-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23081,PHI:124823,UniProt,Q87F37,GenBank,AAO28000,,,Temecula1,copB (PD0101),,,,,,,2371,Xylella fastidiosa,,TemeculaL,Pierce disease of grapes and Citrus variegated chlorosis (cvc),eudicot,4100,Nicotiana benthamiana (no common name found),Petite Havana SR1,,,Leaves,copper homeostasis genes,,,,reduced virulence,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full,,,NN,33554639,PubMed,10.1094/PHYTO-12-20-0531-R,Phytopathology. 2021 Sep;111(9):1520-1529.,lzd0005@auburn.edu,copA mutant showed less symptoms compared to wild type under water and shows high symptoms under CuSO4 treatment.,Q Ge 2021,2021,2 genes,Ge-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23082,PHI:124824,UniProt,A4QTE3,GenBank,EHA52813,,,70-15,Ifa38 (MGG_05096),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),LTH,,,Leaves,3-oxoacyl-CoA reductase,,,,reduced virulence,,,yes,,smaller lesions,,,reduced,,no,sodium dodecyl sulphate (SDS);tunicamycin;dithiothreitol (DTT);calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,39003585,PubMed,10.1111/mpp.13494,Mol Plant Pathol. 2024 Jul;25(7):e13494.,xwchen88@163.com,All the three mutants caused much smaller lesions than the wild-type strain Guy11.,J Su 2024,2024,3 genes,Su-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23083,PHI:124825,UniProt,G4N3I9,GenBank,EHA52664,,,70-15,Phs1 (MGG_04972),chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),LTH,,,Leaves,3R-3-hydroxyacyl-CoA dehydratase,,,,reduced virulence,,,yes,,smaller lesions,,,reduced,,no,sodium dodecyl sulphate (SDS);tunicamycin;dithiothreitol (DTT);calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,39003585,PubMed,10.1111/mpp.13494,Mol Plant Pathol. 2024 Jul;25(7):e13494.,xwchen88@163.com,All the three mutants caused much smaller lesions than the wild-type strain Guy11.,J Su 2024,2024,3 genes,Su-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23084,PHI:124826,UniProt,G4N9V3,GenBank,EHA50405,,,70-15,Tsc13 (MGG_03250),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocots,4530,Oryza sativa (related: rice),LTH,,,Leaves,enoyl reductase,,,,reduced virulence,,,yes,,smaller lesions,,,reduced,,no,sodium dodecyl sulphate (SDS);tunicamycin;dithiothreitol (DTT);calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,39003585,PubMed,10.1111/mpp.13494,Mol Plant Pathol. 2024 Jul;25(7):e13494.,xwchen88@163.com,All the three mutants caused much smaller lesions than the wild-type strain Guy11.,J Su 2024,2024,3 genes,Su-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23085,PHI:124827,UniProt,L7JGR8,GenBank,ELQ67298,,,P131,Atf1,chromosome unknown,,,MoTup1,UniProt: G4MUR7; GenBank: EHA54040,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),LTH; K23,,,Leaves,transcription factor,,,oxidation regulatory pathway,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,33275098,PubMed,10.7554/eLife.61605,Elife. 2020 Dec 4;9:e61605.,zhgzhang@njau.edu.cn,ΔMoatf1 mutant exhibited restricted lesions compared to wild type on both plant cultivar.,X Liu 2020,2020,1 gene,Liu-2020,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23086,PHI:124827,UniProt,L7JGR8,GenBank,ELQ67298,,,P131,Atf1,chromosome unknown,MoAtf1S124A,,MoTup1,UniProt: G4MUR7; GenBank: EHA54040,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),LTH; K23,,,Leaves,transcription factor,,,oxidation regulatory pathway,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,33275098,PubMed,10.7554/eLife.61605,Elife. 2020 Dec 4;9:e61605.,zhgzhang@njau.edu.cn,ΔMoatf1S124A mutant exhibited restricted lesions compared to wild type on both plant cultivar.,X Liu 2020,2020,1 gene,Liu-2020,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23087,PHI:124827,UniProt,L7JGR8,GenBank,ELQ67298,,,P131,Atf1,chromosome unknown,MoAtf1S124D,,MoTup1,UniProt: G4MUR7; GenBank: EHA54040,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),LTH,,,Leaves,transcription factor,,,oxidation regulatory pathway,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,33275098,PubMed,10.7554/eLife.61605,Elife. 2020 Dec 4;9:e61605.,zhgzhang@njau.edu.cn,ΔMoatf1S124D mutant exhibited same lesions same as wild type.,X Liu 2020,2020,1 gene,Liu-2020,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23088,PHI:124827,UniProt,L7JGR8,GenBank,ELQ67298,,,P131,Atf1,chromosome unknown,MoAtf1S124D,,MoTup1,UniProt: G4MUR7; GenBank: EHA54040,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),K23,,,Leaves,transcription factor,,,oxidation regulatory pathway,increased virulence (hypervirulence),,,,,larger lesions,,,,,no,,,,,,,gene deletion: full,,,NN,33275098,PubMed,10.7554/eLife.61605,Elife. 2020 Dec 4;9:e61605.,zhgzhang@njau.edu.cn,MoAtf1S124D expression strains that caused even more lesions than wild type.,X Liu 2020,2020,1 gene,Liu-2020,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23089,PHI:124828,UniProt,G7TG71,GenBank,AEQ96626,,,BLS256,vmsR (XOC_2507),,,,,,,347,Xanthomonas oryzae,,GX01,leaf blight,monocot,4530,Oryza sativa (related: rice),Nipponbare,,,Leaves,regulator,,,,reduced virulence,,,,,smaller lesions,,,increased,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39062838,PubMed,10.3390/ijms25147595,Int J Mol Sci. 2024 Jul 11;25(14):7595.,yqhe@gxu.edu.cn,"ΔvmsR caused disease symptoms with a lesion length of 16.8 ± 1.64 mm, which was significantly less severe than that caused by the GX01 (lesion length 32.53 ± 2.16 mm)",Y Zhang 2024,2024,1 gene,Zhang-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23090,PHI:124829,UniProt,X0LLV0,GenBank,EXM26853,,,25433,Chi20 (FOTG_07042),chromosome unknown,,,,,,5507,Fusarium oxysporum,,f.sp. vasinfectum F327,Fusarium wilt,eudicots,3635,Gossypium hirsutum (related: cotton),XH-14,,,Seedling; Leaves,chitinase,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,39126085,PubMed,10.3390/ijms25158517,Int J Mol Sci. 2024 Aug 4;25(15):8517.,zeganghan@zju.edu.cn,Silencing of FoChi20 on the cotton plants showed noticeably milder disease with a significantly lower disease index than the control.,H Lou 2024,2024,1 gene,Lou-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23091,PHI:124830,UniProt,A0A0J9WHN3,GenBank,KNA97081,,,4287,zfp1,chromosome 5,,,,,,5507,Fusarium oxysporum,,non data found,Fusarium wilt,monocot,261420,Polygonatum kingianum (related: Solomon's seal),,,,Leaves; Rhizomes; Seedlings,zinc fnger transcription factor,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);carbendazim;tebuconazole;Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;carbendazim: CHEBI:3392; ;tebuconazole: CHEBI:81781; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,38992190,PubMed,10.1038/s41598-024-67040-7,Sci Rep. 2024 Jul 11;14(1):16061.,zhlei318@163.com,"In the infection assays, the zfp1 lesion diameters in the detached leaves and rhizomes were signifcantly decreased compared to ZFP1 and zfp1 tZFP1.",J Su 2024,2024,1 gene,Su-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23092,PHI:124831,UniProt,A0A345CWK2,GenBank,AXF77819,,,MDcuke,gh5 (AXF77819.1),,,,,,,65700,Erwinia tracheiphila,,BHKYR,bacterial wilt,eudicot,3663,Curcubita pepo (related: zucchini),,,,Seedling,glycoside hydrolase family 5 protein,,,,reduced virulence,,,,,less symptoms,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33303810,PubMed,10.1038/s41598-020-78157-w,Sci Rep. 2020 Dec 10;10(1):21743.,jorge.rocha@ciad.mx,Plants inoculated with Wt suffered high mortality compared to gh5 mutant,J Rocha 2020,2020,2 genes,Rocha-2020,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23093,PHI:124832,UniProt,A0A345CZK4,GenBank,AXF78871,,,MDcuke,exlx (AXF78871.1),,,,,,,65700,Erwinia tracheiphila,,BHKYR,bacterial wilt,eudicot,3663,Curcubita pepo (related: zucchini),,,,Seedling,expansin,,,,reduced virulence,,,,,less symptoms,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33303810,PubMed,10.1038/s41598-020-78157-w,Sci Rep. 2020 Dec 10;10(1):21743.,jorge.rocha@ciad.mx,Plants inoculated with Wt suffered high mortality compared to exlx mutant,J Rocha 2020,2020,2 genes,Rocha-2020,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23094,PHI:124831,UniProt,A0A345CWK2,GenBank,AXF77819,,,MDcuke,gh5 (AXF77819.1),,,,,,PHI:124832,65700,Erwinia tracheiphila,,BHKYR,bacterial wilt,eudicot,3663,Curcubita pepo (related: zucchini),,,,Seedling,glycoside hydrolase family 5 protein,,,,reduced virulence,,,,,less symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33303810,PubMed,10.1038/s41598-020-78157-w,Sci Rep. 2020 Dec 10;10(1):21743.,jorge.rocha@ciad.mx,"Plants inoculated with Δexlx–gh5 had delayed development of initial wilt symptoms in the inoculated leaf, and delayed appearance of systemic wilt symptoms in a non-inoculated leaf compared to plants inoculated with Wt.",J Rocha 2020,2020,2 genes,Rocha-2020,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23095,PHI:124832,UniProt,A0A345CZK4,GenBank,AXF78871,,,MDcuke,exlx (AXF78871.1),,,,,,PHI:124831,65700,Erwinia tracheiphila,,BHKYR,bacterial wilt,eudicot,3663,Curcubita pepo (related: zucchini),,,,Seedling,expansin,,,,reduced virulence,,,,,less symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33303810,PubMed,10.1038/s41598-020-78157-w,Sci Rep. 2020 Dec 10;10(1):21743.,jorge.rocha@ciad.mx,"Plants inoculated with Δexlx–gh5 had delayed development of initial wilt symptoms in the inoculated leaf, and delayed appearance of systemic wilt symptoms in a non-inoculated leaf compared to plants inoculated with Wt.",J Rocha 2020,2020,2 genes,Rocha-2020,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23096,PHI:124833,UniProt,E3Q2F8,GenBank,EFQ25259,,,M1.001,Con7 (XP_008089279.1),,,,,,,31870,Colletotrichum graminicola,,M2,stalk rot and leaf blight of maize,monocot,4577,Zea mays (related: maize),Xianyu 335,,,Leaves,C2H2 transcription factor,,,,loss of pathogenicity,,,,,no symptom,reduced,,reduced,wild type,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39057380,PubMed,10.3390/jof10070495,J Fungi (Basel). 2024 Jul 17;10(7):495.,liuzhiqiang@hainanu.edu.cn,"Disrupting Cgrcon7 led to a decreased growth rate, conidial production and shows complete loss of virulence.",S Zhou 2024,2024,2 genes,Zhou-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23097,PHI:124833,UniProt,E3Q2F8,GenBank,EFQ25259,,,M1.001,Con7 (XP_008089279.1),,,,,,,31870,Colletotrichum graminicola,,M2,stalk rot and leaf blight of maize,eudicot,3981,Hevea brasiliensis (related: rubber tree),,,,Leaves,C2H2 transcription factor,,,,loss of pathogenicity,,,,,no symptom,reduced,,reduced,wild type,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39057380,PubMed,10.3390/jof10070495,J Fungi (Basel). 2024 Jul 17;10(7):495.,liuzhiqiang@hainanu.edu.cn,"Disrupting Cgrcon7 led to a decreased growth rate, conidial production and shows complete loss of virulence.",S Zhou 2024,2024,2 genes,Zhou-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23098,PHI:124834,UniProt,A0A9P5K9T3,GenBank,KAF4867264,,,CAD2,Con7 (XP_036502431.1),,,,,,,690259,Colletotrichum siamense,,,stalk rot and leaf blight of maize,monocot,4577,Zea mays (related: maize),Xianyu 335,,,Leaves,C2H2 transcription factor,,,,loss of pathogenicity,,,,,no symptom,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39057380,PubMed,10.3390/jof10070495,J Fungi (Basel). 2024 Jul 17;10(7):495.,liuzhiqiang@hainanu.edu.cn,"Disrupting Cscon7 led to a decreased growth rate, conidial production and shows complete loss of virulence.",S Zhou 2024,2024,2 genes,Zhou-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23099,PHI:124834,UniProt,A0A9P5K9T3,GenBank,KAF4867264,,,CAD2,Con7 (XP_036502431.1),,,,,,,690259,Colletotrichum siamense,,,stalk rot and leaf blight of maize,monocot,3981,Hevea brasiliensis (related: rubber tree),Xianyu 335,,,Leaves,C2H2 transcription factor,,,,loss of pathogenicity,,,,,no symptom,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39057380,PubMed,10.3390/jof10070495,J Fungi (Basel). 2024 Jul 17;10(7):495.,liuzhiqiang@hainanu.edu.cn,"Disrupting Cscon7 led to a decreased growth rate, conidial production and shows complete loss of virulence.",S Zhou 2024,2024,2 genes,Zhou-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23100,PHI:124835,UniProt,H1VRI6,GenBank,CCF42842,,,IMI 349063,Acb1 (XP_018157555.1),,,,,,,80884,Colletotrichum higginsianum,759273,Ch-1 (IMI349063),anthracnose leaf spot,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,acyl CoA binding protein,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33567906,PubMed,10.1094/PHYTO-01-21-0028-R,Phytopathology. 2021 Sep;111(9):1571-1582.,luzheng@mail.hzau.edu.cn,ChAcb1 deletion mutants showed significantly reduced virulence on inoculated leaves.,Y Yan 2021,2021,1 gene,Yan-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23101,PHI:124836,UniProt,P13649,GenBank,CAA32410,,,ATCC 10231,URA3,,,,,,,5476,Candida albicans,237561,SC5314,disseminated candidiasis,rodents,10090,Mus musculus (related: house mouse),ICR,,,"macrophage, Kidneys",uridine auxotroph,,,mkc1 MAPK pathway,reduced virulence,,,,,low disease severity,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39115319,PubMed,10.1128/msphere.00287-24,mSphere. 2024 Aug 8:e0028724.,treynol6@utk.edu,Mice infected with the ura3ΔΔ mutant exhibited increased survival and reduced kidney fungal burden compared with mice infected with wild type.,M M Mangrum 2024,2024,1 gene,Mangrum-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23102,PHI:124837,UniProt,I1S095,GenBank,CEF75466,,,PH-1,Ras2,chromosome 1,,,,,,48490,Fusarium circinatum,,FSP34,pine pitch canker,seed plants,71645,Pinus patula,,,,Seedlings,GTPases,,,,reduced virulence,,,,,smaller lesions,increased,reduced,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,33639303,PubMed,10.1016/j.fgb.2021.103541,Fungal Genet Biol. 2021 May;150:103541.,mmatshepho.phasha@fabi.up.ac.za,"Knockout mutant strain produced significantly delayed conidial germination, smaller colonies and lesions compared to the complementation mutant and wild type strains.",M M Phasha 2021,2021,1 gene,Phasha-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23103,PHI:124838,UniProt,I1RSZ4,GenBank,CEF83368,,,PH-1,Chy1 (FGSG_07281),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,Wheat heads; Corn silk,CHY-type zinc finger protein,,,,reduced virulence,,,,,less symptoms,reduced,reduced,reduced ; defective,,no,carbendazim;tebuconazole;nocodazole,carbendazim: CHEBI:3392; ;tebuconazole: CHEBI:81781; ;nocodazole: CHEBI:34892,,,,,gene deletion: full ; gene complementation,,,NN,33369502,PubMed,10.1094/MPMI-07-20-0206-R,Mol Plant Microbe Interact. 2021 Apr;34(4):362-375.,huaigu@jaas.ac.cn,The wheat infection assay indicated that the Fgchy1 mutant significantly decreased virulence.,S Cao 2021,2021,3 genes,Cao-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23104,PHI:124839,UniProt,I1RYK6,GenBank,CEF85222,,,PH-1,Chy2 (FGSG_09462),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,Wheat heads,CHY-type zinc finger protein,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,33369502,PubMed,10.1094/MPMI-07-20-0206-R,Mol Plant Microbe Interact. 2021 Apr;34(4):362-375.,huaigu@jaas.ac.cn,The wheat infection assay indicated that the Fgchy2 mutant showed similar virulence.,S Cao 2021,2021,3 genes,Cao-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23105,PHI:124840,UniProt,I1RD47,GenBank,CEF73680,,,PH-1,Chy3 (FGSG_01536),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,Wheat heads,CHY-type zinc finger protein,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,33369502,PubMed,10.1094/MPMI-07-20-0206-R,Mol Plant Microbe Interact. 2021 Apr;34(4):362-375.,huaigu@jaas.ac.cn,The wheat infection assay indicated that the Fgchy3 mutant showed similar virulence.,S Cao 2021,2021,3 genes,Cao-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23106,PHI:124841,UniProt,G4NJG9,GenBank,EHA46385,,,70-15,Pyr4 (MGG_12634),chromosome 7,,,Atg5,UniProt: Q525E4; GenBank: ABO93146,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,dihydroorotase,,,,reduced virulence,,,yes,,low disease severity,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);paraquat;NaCl;KCl;rose bengal (RB),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;paraquat: CHEBI:34905; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;rose bengal (RB): CHEBI:52261,,,,,gene deletion: full ; gene complementation,,,NN,39010102,PubMed,10.1186/s12964-024-01741-4,Cell Commun Signal. 2024 Jul 15;22(1):362.,fuchenglin@zju.edu.cn,"Deletion of MoPYR4 led to defects in growth, conidiation and weakened fungal pathogenicity.",J Y Wang 2024,2024,1 gene,Wang-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23107,PHI:124841,UniProt,G4NJG9,GenBank,EHA46385,,,70-15,Pyr4 (MGG_12634),chromosome 7,,,Atg5,UniProt: Q525E4; GenBank: ABO93146,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),ZJ-8,,,Leaves,dihydroorotase,,,,reduced virulence,,,yes,,low disease severity,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);paraquat;NaCl;KCl;rose bengal (RB),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;paraquat: CHEBI:34905; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;rose bengal (RB): CHEBI:52261,,,,,gene deletion: full ; gene complementation,,,NN,39010102,PubMed,10.1186/s12964-024-01741-4,Cell Commun Signal. 2024 Jul 15;22(1):362.,fuchenglin@zju.edu.cn,"Deletion of MoPYR4 led to defects in growth, conidiation and weakened fungal pathogenicity.",J Y Wang 2024,2024,1 gene,Wang-2024,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23108,PHI:124842,UniProt,G4NGT5,GenBank,EHA47445,,,70-15,Alb1,chromosome 6,,,,,,318829,Pyricularia oryzae,242507,70-15,rice blast,monocot,4513,Hordeum vulgare (related: barley),,,,Leaves,melanin synthesis genes,,,,loss of pathogenicity,,,,,no lesion,wild type,,wild type,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,33189072,PubMed,10.1016/j.micres.2020.126620,Microbiol Res. 2021 Jan;242:126620.,jplu@zju.edu.cn,"Δalb1, Δbuf1, and Δrsy1 mutants from both wild-type strains lost virulence, whereas the respective complementation strains regained virulence similar to that of the wild-type strains.",S Zhu 2021,2021,3 genes,Zhu-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23109,PHI:124842,UniProt,G4NGT5,GenBank,EHA47445,,,70-15,Alb1,chromosome 6,,,,,,318829,Pyricularia oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),,,,Leaves,melanin synthesis genes,,,,loss of pathogenicity,,,,,no lesion,reduced,,increased,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,33189072,PubMed,10.1016/j.micres.2020.126620,Microbiol Res. 2021 Jan;242:126620.,jplu@zju.edu.cn,"Δalb1, Δbuf1, and Δrsy1 mutants from both wild-type strains lost virulence, whereas the respective complementation strains regained virulence similar to that of the wild-type strains.",S Zhu 2021,2021,3 genes,Zhu-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23110,PHI:124842,UniProt,G4NGT5,GenBank,EHA47445,,,70-15,Alb1,chromosome 6,,,,,,318829,Pyricularia oryzae,242507,70-15,rice blast,monocot,4530,Oryza sativa (related: rice),,,,Leaves,melanin synthesis genes,,,,loss of pathogenicity,,,,,no lesion,wild type,,wild type,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,33189072,PubMed,10.1016/j.micres.2020.126620,Microbiol Res. 2021 Jan;242:126620.,jplu@zju.edu.cn,"Δalb1, Δbuf1, and Δrsy1 mutants from both wild-type strains lost virulence, whereas the respective complementation strains regained virulence similar to that of the wild-type strains.",S Zhu 2021,2021,3 genes,Zhu-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23111,PHI:124842,UniProt,G4NGT5,GenBank,EHA47445,,,70-15,Alb1,chromosome 6,,,,,,318829,Pyricularia oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),,,,Leaves,melanin synthesis genes,,,,loss of pathogenicity,,,,,no lesion,reduced,,increased,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,33189072,PubMed,10.1016/j.micres.2020.126620,Microbiol Res. 2021 Jan;242:126620.,jplu@zju.edu.cn,"Δalb1, Δbuf1, and Δrsy1 mutants from both wild-type strains lost virulence, whereas the respective complementation strains regained virulence similar to that of the wild-type strains.",S Zhu 2021,2021,3 genes,Zhu-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23112,PHI:124843,UniProt,P56221,GenBank,EHA52765,,,70-15,Rsy1,chromosome 3,,,,,,318829,Pyricularia oryzae,242507,70-15,rice blast,monocot,4513,Hordeum vulgare (related: barley),,,,Leaves,melanin synthesis genes,,,,loss of pathogenicity,,,,,no lesion,wild type,,wild type,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,33189072,PubMed,10.1016/j.micres.2020.126620,Microbiol Res. 2021 Jan;242:126620.,jplu@zju.edu.cn,"Δalb1, Δbuf1, and Δrsy1 mutants from both wild-type strains lost virulence, whereas the respective complementation strains regained virulence similar to that of the wild-type strains.",S Zhu 2021,2021,3 genes,Zhu-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23113,PHI:124843,UniProt,P56221,GenBank,EHA52765,,,70-15,Rsy1,chromosome 3,,,,,,318829,Pyricularia oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),,,,Leaves,melanin synthesis genes,,,,loss of pathogenicity,,,,,no lesion,reduced,,increased,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,33189072,PubMed,10.1016/j.micres.2020.126620,Microbiol Res. 2021 Jan;242:126620.,jplu@zju.edu.cn,"Δalb1, Δbuf1, and Δrsy1 mutants from both wild-type strains lost virulence, whereas the respective complementation strains regained virulence similar to that of the wild-type strains.",S Zhu 2021,2021,3 genes,Zhu-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23114,PHI:124843,UniProt,P56221,GenBank,EHA52765,,,70-15,Rsy1,chromosome 3,,,,,,318829,Pyricularia oryzae,242507,70-15,rice blast,monocot,4530,Oryza sativa (related: rice),,,,Leaves,melanin synthesis genes,,,,loss of pathogenicity,,,,,no lesion,wild type,,wild type,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,33189072,PubMed,10.1016/j.micres.2020.126620,Microbiol Res. 2021 Jan;242:126620.,jplu@zju.edu.cn,"Δalb1, Δbuf1, and Δrsy1 mutants from both wild-type strains lost virulence, whereas the respective complementation strains regained virulence similar to that of the wild-type strains.",S Zhu 2021,2021,3 genes,Zhu-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23115,PHI:124843,UniProt,P56221,GenBank,EHA52765,,,70-15,Rsy1,chromosome 3,,,,,,318829,Pyricularia oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),,,,Leaves,melanin synthesis genes,,,,loss of pathogenicity,,,,,no lesion,reduced,,increased,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,33189072,PubMed,10.1016/j.micres.2020.126620,Microbiol Res. 2021 Jan;242:126620.,jplu@zju.edu.cn,"Δalb1, Δbuf1, and Δrsy1 mutants from both wild-type strains lost virulence, whereas the respective complementation strains regained virulence similar to that of the wild-type strains.",S Zhu 2021,2021,3 genes,Zhu-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23116,PHI:124844,UniProt,Q12634,GenBank,EHA56411,,,70-15,Buf1,chromosome 1,,,,,,318829,Pyricularia oryzae,242507; no data found,70-15; Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),,,,Leaves,melanin synthesis genes,,,,loss of pathogenicity,,,,,no lesion,reduced,,wild type,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,33189072,PubMed,10.1016/j.micres.2020.126620,Microbiol Res. 2021 Jan;242:126620.,jplu@zju.edu.cn,"Δalb1, Δbuf1, and Δrsy1 mutants from both wild-type strains lost virulence, whereas the respective complementation strains regained virulence similar to that of the wild-type strains.",S Zhu 2021,2021,3 genes,Zhu-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23117,PHI:124844,UniProt,Q12634,GenBank,EHA56411,,,70-15,Buf1,chromosome 1,,,,,,318829,Pyricularia oryzae,242507; no data found,70-15; Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),,,,Leaves,melanin synthesis genes,,,,loss of pathogenicity,,,,,no lesion,reduced,,wild type,reduced,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,33189072,PubMed,10.1016/j.micres.2020.126620,Microbiol Res. 2021 Jan;242:126620.,jplu@zju.edu.cn,"Δalb1, Δbuf1, and Δrsy1 mutants from both wild-type strains lost virulence, whereas the respective complementation strains regained virulence similar to that of the wild-type strains.",S Zhu 2021,2021,3 genes,Zhu-2021,BATCH_136,2024-08-01,MC,,,,,,,,,,,,,
,,Record 23118,PHI:124845,UniProt,Q70YY7,GenBank,CAD30840,,,Beta,Ste12 (AJ459778),,,,,,,690256,Colletotrichum fructicola,,1104-6,anthracnose,eudicots,3750,Malus domestica (related: apple),Gala,,,Leaves; fruit,transcription factor,,,glyoxylate and dicarboxylate metabolism pathways,loss of pathogenicity,,,yes,,no lesion,wild type,increased,wild type,reduced,no,,,,,,,gene deletion: full,,,NN,33067192,PubMed,10.1128/AEM.02212-20,Appl Environ Microbiol. 2020 Dec 17;87(1):e02212-20.,xiaofeiliang@nwsuaf.edu.cn,"WT induced dark necrotic lesions at 5 days postinoculation (dpi), whereas no lesion was observed with CfSte12 deletion mutants on apple leaves and fruit; whereas increased lesion is seen in wounded fruit.",W Liu 2020,2020,1 gene,Liu-2020-Transcription Factor CfSte12 of Colle,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23119,PHI:124846,UniProt,A0A7G7Y7P2,GenBank,QNH90388,,,BRS1,RS_CRZ1,,,,,,,456999,Rhizoctonia solani,983506,AG1-IA,rice sheath blight,eudicots,4081,Solanum lycopersicum (related: tomato),Pusa Ruby,,,Leaves,C2H2-type transcription factor,,,,reduced virulence,,,yes,,reduced lesions,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,33030394,PubMed,10.1094/MPMI-05-20-0121-R,Mol Plant Microbe Interact. 2021 Jan;34(1):26-38.,jmsgopal@nipgr.ac.in,"The disease reduction was most drastic in RS_CRZ1- silenced plants, wherein a majority of the infected leaves (approximately 90%) showed minimal infection and only a few leaves had merged lesions.",S Ghosh 2021,2021,3 genes,"Ghosh-2021-RS_CRZ1, a C2H2-Type Transcription",BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23120,PHI:124847,UniProt,A0A8H7I0Z7,GenBank,KAF8714525,,,AG1-IA WGL,RS_GH16,,,,,,,456999,Rhizoctonia solani,983506,AG1-IA,rice sheath blight,eudicots,4081,Solanum lycopersicum (related: tomato),Pusa Ruby,,,Leaves,glycoside hydrolase 16 domain–containing gene,,,,reduced virulence,,,yes,,reduced lesions,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,33030394,PubMed,10.1094/MPMI-05-20-0121-R,Mol Plant Microbe Interact. 2021 Jan;34(1):26-38.,jmsgopal@nipgr.ac.in,"The disease reduction was in RS_GH16- silenced plants, wherein a majority of the infected leaves showed merged lesions.",S Ghosh 2021,2021,3 genes,"Ghosh-2021-RS_CRZ1, a C2H2-Type Transcription",BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23121,PHI:124848,UniProt,A0A8H3I0V7,GenBank,CAE7189375,,,AG5,RS_TF3,,,,,,,456999,Rhizoctonia solani,983506,AG1-IA,rice sheath blight,eudicots,4081,Solanum lycopersicum (related: tomato),Pusa Ruby,,,Leaves,GAL4-like Zn2Cys6 domain–containing transcription factor,,,,reduced virulence,,,yes,,reduced lesions,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,33030394,PubMed,10.1094/MPMI-05-20-0121-R,Mol Plant Microbe Interact. 2021 Jan;34(1):26-38.,jmsgopal@nipgr.ac.in,"The disease reduction was in RS_TF3- silenced plants, wherein a majority of the infected leaves showed merged lesions.",S Ghosh 2021,2021,3 genes,"Ghosh-2021-RS_CRZ1, a C2H2-Type Transcription",BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23122,PHI:124849,UniProt,G4MZ74,GenBank,EHA55348,,,70-15,MUG1 (MGG_12307),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4530,Oryza sativa (related: rice),LTH,,,Leaves,magnaporthe-unique gene,,,,reduced virulence,,,,,fewer lesions,reduced,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39194837,PubMed,10.3390/jof10080511,J Fungi (Basel). 2024 Jul 23;10(8):511.,yangj@cau.edu.cn,MUG1ko1 produced noticeably fewer lesions compared to wild type.,H Zhang 2024,2024,4 genes,Zhang-2024-Magnaporthe-Unique Gene MUG1 Is Imp,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23123,PHI:124850,UniProt,G4MSR0,GenBank,EHA55481,,,70-15,MUG2 (MGG_15077),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4530,Oryza sativa (related: rice),LTH,,,Leaves,magnaporthe-unique gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39194837,PubMed,10.3390/jof10080511,J Fungi (Basel). 2024 Jul 23;10(8):511.,yangj@cau.edu.cn,"MUG2ko1, MUG3ko1 and MUG4ko1 generated comparative disease lesions with strain P131.",H Zhang 2024,2024,4 genes,Zhang-2024-Magnaporthe-Unique Gene MUG1 Is Imp,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23124,PHI:124851,UniProt,G4MNQ0,GenBank,EHA56266,,,70-15,MUG3 (MGG_16034),chromosome 1,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4530,Oryza sativa (related: rice),LTH,,,Leaves,magnaporthe-unique gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39194837,PubMed,10.3390/jof10080511,J Fungi (Basel). 2024 Jul 23;10(8):511.,yangj@cau.edu.cn,"MUG2ko1, MUG3ko1 and MUG4ko1 generated comparative disease lesions with strain P131.",H Zhang 2024,2024,4 genes,Zhang-2024-Magnaporthe-Unique Gene MUG1 Is Imp,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23125,PHI:124852,UniProt,G4NLL2,GenBank,EHA46065,,,70-15,MUG4 (MGG_17927),chromosome 7,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4530,Oryza sativa (related: rice),LTH,,,Leaves,magnaporthe-unique gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39194837,PubMed,10.3390/jof10080511,J Fungi (Basel). 2024 Jul 23;10(8):511.,yangj@cau.edu.cn,"MUG2ko1, MUG3ko1 and MUG4ko1 generated comparative disease lesions with strain P131.",H Zhang 2024,2024,4 genes,Zhang-2024-Magnaporthe-Unique Gene MUG1 Is Imp,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23126,PHI:124849,UniProt,G4MZ74,GenBank,EHA55348,,,70-15,MUG1 (MGG_12307),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4513,Hordeum vulgare (related: barley),E8,,,Leaves,magnaporthe-unique gene,,,,reduced virulence,,,,,fewer lesions,reduced,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39194837,PubMed,10.3390/jof10080511,J Fungi (Basel). 2024 Jul 23;10(8):511.,yangj@cau.edu.cn,MUG1ko1 produced noticeably fewer lesions compared to wild type.,H Zhang 2024,2024,4 genes,Zhang-2024-Magnaporthe-Unique Gene MUG1 Is Imp,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23127,PHI:124850,UniProt,G4MSR0,GenBank,EHA55481,,,70-15,MUG2 (MGG_15077),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4513,Hordeum vulgare (related: barley),E8,,,Leaves,magnaporthe-unique gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39194837,PubMed,10.3390/jof10080511,J Fungi (Basel). 2024 Jul 23;10(8):511.,yangj@cau.edu.cn,"MUG2ko1, MUG3ko1 and MUG4ko1 generated comparative disease lesions with strain P131.",H Zhang 2024,2024,4 genes,Zhang-2024-Magnaporthe-Unique Gene MUG1 Is Imp,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23128,PHI:124851,UniProt,G4MNQ0,GenBank,EHA56266,,,70-15,MUG3 (MGG_16034),chromosome 1,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4513,Hordeum vulgare (related: barley),E8,,,Leaves,magnaporthe-unique gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39194837,PubMed,10.3390/jof10080511,J Fungi (Basel). 2024 Jul 23;10(8):511.,yangj@cau.edu.cn,"MUG2ko1, MUG3ko1 and MUG4ko1 generated comparative disease lesions with strain P131.",H Zhang 2024,2024,4 genes,Zhang-2024-Magnaporthe-Unique Gene MUG1 Is Imp,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23129,PHI:124852,UniProt,G4NLL2,GenBank,EHA46065,,,70-15,MUG4 (MGG_17927),chromosome 7,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4513,Hordeum vulgare (related: barley),E8,,,Leaves,magnaporthe-unique gene,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39194837,PubMed,10.3390/jof10080511,J Fungi (Basel). 2024 Jul 23;10(8):511.,yangj@cau.edu.cn,"MUG2ko1, MUG3ko1 and MUG4ko1 generated comparative disease lesions with strain P131.",H Zhang 2024,2024,4 genes,Zhang-2024-Magnaporthe-Unique Gene MUG1 Is Imp,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23130,PHI:124853,UniProt,X0J790,GenBank,EXL97073,,,54006,Rnt2 (FOIG_10760),chromosome unknown,,,,,,5507,Fusarium oxysporum,1229665,f.sp. Cubense tropic race 4 (Foc TR4),Fusarium wilt,monocot,4641,Musa acuminata (related: dwarf banana),Brazilian,,,Seedling; Roots,effector protein,,,,effector (plant avirulence determinant),,,yes,,low disease severity,wild type,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39118198,PubMed,10.1111/mpp.13502,Mol Plant Pathol. 2024 Aug;25(8):e13502.,yunfengli@scau.edu.cn,The disease index of FocRnt2 deletion mutant-inoculated banana plants was significantly lower than those of WT- and ΔFocRnt2-com-inoculated plants.,Y He 2024,2024,1 gene,He-2024-A ribonuclease T2 protein FocRnt2 cont,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23131,PHI:124854,UniProt,D6CK46,GenBank,CAZ15839,,,GPE PC73,virB11,,,,,,,29447,Xanthomonas albilineans,,JG43,leaf scald disease,monocot,4547,Saccharum officinarum (related: sugarcane),GT46,,,Leaves,type IV secretion system (T4SS) gene,,,chemotaxis signalling pathway,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39223938,PubMed,10.1111/mpp.70001,Mol Plant Pathol. 2024 Sep;25(9):e70001.,zmuqing@163.com,"The DI induced by the wildtype JG43 was 54.76; In contrast, the mutant strain (ΔvirB11) and its vector control (PΔvirB11) showed significantly reduced DI values of 13.45 and 14.79, respectively (p< 0.01).",M Li 2024,2024,6 genes,"Li-2024-VirB11, a traffic ATPase, mediated fla",BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23132,PHI:124855,UniProt,D6CK55,GenBank,CAZ15847,,,GPE PC73,virB4,,,,,,,29447,Xanthomonas albilineans,,JG43,leaf scald disease,monocot,4547,Saccharum officinarum (related: sugarcane),GT46,,,Leaves,type IV secretion system (T4SS) gene,,,chemotaxis signalling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39223938,PubMed,10.1111/mpp.70001,Mol Plant Pathol. 2024 Sep;25(9):e70001.,zmuqing@163.com,"DI values for the mutants ΔvirB4, ΔvirB5, ΔvirB8, ΔvirB10, and ΔvirD4 were not significantly different from that of the wild-type JG43.",M Li 2024,2024,6 genes,"Li-2024-VirB11, a traffic ATPase, mediated fla",BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23133,PHI:124856,UniProt,D6CK54,GenBank,CAZ15846,,,GPE PC73,virB5,,,,,,,29447,Xanthomonas albilineans,,JG43,leaf scald disease,monocot,4547,Saccharum officinarum (related: sugarcane),GT46,,,Leaves,type IV secretion system (T4SS) gene,,,chemotaxis signalling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39223938,PubMed,10.1111/mpp.70001,Mol Plant Pathol. 2024 Sep;25(9):e70001.,zmuqing@163.com,"DI values for the mutants ΔvirB4, ΔvirB5, ΔvirB8, ΔvirB10, and ΔvirD4 were not significantly different from that of the wild-type JG43.",M Li 2024,2024,6 genes,"Li-2024-VirB11, a traffic ATPase, mediated fla",BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23134,PHI:124857,UniProt,D2UE06,GenBank,CBA16332,,,GPE PC73,virB8,,,,,,,29447,Xanthomonas albilineans,,JG43,leaf scald disease,monocot,4547,Saccharum officinarum (related: sugarcane),GT46,,,Leaves,type IV secretion system (T4SS) gene,,,chemotaxis signalling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39223938,PubMed,10.1111/mpp.70001,Mol Plant Pathol. 2024 Sep;25(9):e70001.,zmuqing@163.com,"DI values for the mutants ΔvirB4, ΔvirB5, ΔvirB8, ΔvirB10, and ΔvirD4 were not significantly different from that of the wild-type JG43.",M Li 2024,2024,6 genes,"Li-2024-VirB11, a traffic ATPase, mediated fla",BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23135,PHI:124858,UniProt,D2UE04,GenBank,CBA16330,,,GPE PC73,virB10,,,,,,,29447,Xanthomonas albilineans,,JG43,leaf scald disease,monocot,4547,Saccharum officinarum (related: sugarcane),GT46,,,Leaves,type IV secretion system (T4SS) gene,,,chemotaxis signalling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39223938,PubMed,10.1111/mpp.70001,Mol Plant Pathol. 2024 Sep;25(9):e70001.,zmuqing@163.com,"DI values for the mutants ΔvirB4, ΔvirB5, ΔvirB8, ΔvirB10, and ΔvirD4 were not significantly different from that of the wild-type JG43.",M Li 2024,2024,6 genes,"Li-2024-VirB11, a traffic ATPase, mediated fla",BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23136,PHI:124859,UniProt,D6CK43,GenBank,CAZ15838,,,GPE PC73,virD4,,,,,,,29447,Xanthomonas albilineans,,JG43,leaf scald disease,monocot,4547,Saccharum officinarum (related: sugarcane),GT46,,,Leaves,type IV secretion system (T4SS) gene,,,chemotaxis signalling pathway,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39223938,PubMed,10.1111/mpp.70001,Mol Plant Pathol. 2024 Sep;25(9):e70001.,zmuqing@163.com,"DI values for the mutants ΔvirB4, ΔvirB5, ΔvirB8, ΔvirB10, and ΔvirD4 were not significantly different from that of the wild-type JG43.",M Li 2024,2024,6 genes,"Li-2024-VirB11, a traffic ATPase, mediated fla",BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23137,PHI:124860,UniProt,A1TS62,GenBank,ABM33800,,,AAC00-1,ClpA,,,,RepA,UniProt: A1TJ61; GenBank: ABM30999,,80869,Acidovorax citrulli,,xjL12,bacterial fruit blotch,eudicots,3656,Cucumis melo (related: muskmelon),Huanghou,,,Seedlings,protease,,,,reduced virulence,,,,,less symptoms,,,wild type,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,39109209,PubMed,10.3389/fmicb.2024.1431029,Front Microbiol. 2024 Jul 23;15:1431029.,tianyanli@njau.edu.cn,"Compared to WT, the virulence of ΔClpA on the cotyledons of melon seedlings was significantly reduced.",S Ziye 2024,2024,2 genes,Ziye-2024-ClpA affects the virulence of Paraci,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23138,PHI:124861,UniProt,A1TJ61,GenBank,ABM30999,,,AAC00-1,RepA,,,,,,,80869,Acidovorax citrulli,,xjL12,bacterial fruit blotch,eudicots,3656,Cucumis melo (related: muskmelon),Huanghou,,,Seedlings,protease,,,,reduced virulence,,,,,less symptoms,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39109209,PubMed,10.3389/fmicb.2024.1431029,Front Microbiol. 2024 Jul 23;15:1431029.,tianyanli@njau.edu.cn,"Compared to WT, ΔRepA showed significantly reduced virulence on melon cotyledons.",S Ziye 2024,2024,2 genes,Ziye-2024-ClpA affects the virulence of Paraci,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23139,PHI:124862,UniProt,G2WYX6,GenBank,EGY21778,,,VdLs.17,P5CDH (VDAG_03218),chromosome 6,,,,,,27337,Verticillium dahliae,,Vd080,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),Jimian11,,,Seedlings; stem,ALDH_F4-17 family of carboxylate dehydrogenases,,,metabolic pathway,increased virulence (hypervirulence),,,no,,high disease severity,increased,,increased,,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);tebuconazole;Congo red,sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;tebuconazole: CHEBI:81781; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39113834,PubMed,10.3389/fmicb.2024.1429755,Front Microbiol. 2024 Jul 24;15:1429755.,heqinanyang@163.com,"At 26 dpi, the cotton plants infected with the ΔVdP5CDH strains showed severe leaf chlorosis and browning of vascular bundles in the longitudinal section of the root compared to the plants inoculated with the WT and C-ΔVdP5CDH strains.",W Sun 2024,2024,1 gene,Sun-2024-VdP5CDH is involved in melanin format,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23140,PHI:124863,UniProt,D3J126,GenBank,ADC35362,,,,HogA,,,,,,,5599,Alternaria alternata,,ATCC 66981,brown spot disease,eudicot,4081,Solanum lycopersicum (related: tomato),,,,fruit,mitogen activated protein kinase,,,HOG pathway,reduced virulence,,,,,smaller lesions,,,wild type,reduced,no,sorbitol;hydrogen peroxide (H2O2);menadione;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;menadione: CHEBI:28869; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,33104446,PubMed,10.1094/MPMI-06-20-0165-R,Mol Plant Microbe Interact. 2020 Dec;33(12):1405-1410.,reinhard.fischer@KIT.edu,HogA mutant strain strongly impaired in the ability to colonize either of the fruit.,O Igbalajobi 2020,2020,1 gene,Igbalajobi-2020-The HOG Pathway Plays Differen,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23141,PHI:124863,UniProt,D3J126,GenBank,ADC35362,,,,HogA,,,,,,,5599,Alternaria alternata,,ATCC 66981,brown spot disease,eudicot,3750,Malus domestica (related: apple),,,,fruit,mitogen activated protein kinase,,,HOG pathway,reduced virulence,,,,,smaller lesions,,,wild type,reduced,no,sorbitol;hydrogen peroxide (H2O2);menadione;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;menadione: CHEBI:28869; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,33104446,PubMed,10.1094/MPMI-06-20-0165-R,Mol Plant Microbe Interact. 2020 Dec;33(12):1405-1410.,reinhard.fischer@KIT.edu,HogA mutant strain strongly impaired in the ability to colonize either of the fruit.,O Igbalajobi 2020,2020,1 gene,Igbalajobi-2020-The HOG Pathway Plays Differen,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23142,PHI:124864,UniProt,A0A0K0GGU1,GenBank,ACD57439,,,,phaC,,,,,,,347,Xanthomonas oryzae,360094,"pv. Oryzae, strain PXO99A",leaf blight,monocot,4530,Oryza sativa (related: rice),IR24; Nipponbare,,,Leaves,polyhydroxyalkanoates,,,PHA metabolic pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39138326,PubMed,10.1038/s41598-024-69621-y,Sci Rep. 2024 Aug 13;14(1):18781. doi: 10.1038/s41598-024-69621-y,Miao@hainanu.edu.cn,ΔphaC displayed reduced virulence in terms of lesion length compared with the wild-type strain.,X Gao 2024,2024,1 gene,Gao-2024-Effect of mutation of phaC on carbon,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23143,PHI:124864,UniProt,A0A0K0GGU1,GenBank,ACD57439,,,,phaC,,,,,,,347,Xanthomonas oryzae,360094,"pv. Oryzae, strain PXO99A",leaf blight,monocot,4530,Oryza sativa (related: rice),IR24,,,Leaves,polyhydroxyalkanoates,,,PHA metabolic pathway,reduced virulence,,,,,,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39138326,PubMed,10.1038/s41598-024-69621-y,Sci Rep. 2024 Aug 13;14(1):18781. doi: 10.1038/s41598-024-69621-y,Miao@hainanu.edu.cn,Overexpression of phaC displayed reduced virulence in terms of lesion length compared with the wild-type strain.,X Gao 2024,2024,1 gene,Gao-2024-Effect of mutation of phaC on carbon,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23144,PHI:124865,UniProt,A0A5N5D6F9,GenBank,KAB2572992,,,LA-SOL3,LysM1,,,,,,,45133,Lasiodiplodia theobromae,,CSS-01s,grapevine canker disease,eudicots,29760,Vitis vinifera (related: wine grape),Summar Black,,,Shoots,secreted protein,,,,increased virulence (hypervirulence),,,,,larger lesions,,,wild type,,,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,32788891,PubMed,10.5423/PPJ.OA.05.2020.0084,Plant Pathol J. 2020 Aug 1;36(4):323-334.,pjb169961@163.com,Overexpressed transformants of LtLysM1 displayed increased virulence on grapevine shoots in comparison with that of wild type CSS-01s.,D L Harishchandra 2020,2020,1 gene,Harishchandra-2020-A LysM Domain-Containing Pr,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23145,PHI:124865,UniProt,A0A5N5D6F9,GenBank,KAB2572992,,,LA-SOL3,LysM1,,,,,,,45133,Lasiodiplodia theobromae,,CSS-01s,grapevine canker disease,eudicots,29760,Vitis vinifera (related: wine grape),Summar Black,,,Shoots,secreted protein,,,,reduced virulence,,,,,smaller lesions,,,reduced,,,,,,,,,altered gene expression / gene regulation: silencing,,,NN,32788891,PubMed,10.5423/PPJ.OA.05.2020.0084,Plant Pathol J. 2020 Aug 1;36(4):323-334.,pjb169961@163.com,RNAi transformants LtLysM1-RNAi1 and LtLysM1- RNAi2 exhibited obviously smaller lesion lengths compared to wild type CSS-01s.,D L Harishchandra 2020,2020,1 gene,Harishchandra-2020-A LysM Domain-Containing Pr,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23146,PHI:124866,UniProt,G4NH12,GenBank,EHA47522,,,70-15,SMI1 (MGG_03970),chromosome 6,,,MoOsm1; MoMps1,UniProt: Q9UV51; GenBank: AAF09475; UniProt: O13352; GenBank: AAC63682,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),Golden Promise,,,Leaves,MAP kinase-interacting protein,,,mitogen-activated protein kinase (MAPK) signalling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39034619,PubMed,10.1111/mpp.13493,Mol Plant Pathol. 2024 Jul;25(7):e13493.,panyuemin2008@163.com,ΔMosmi1 mutant caused more restricted lesions in both intact and wounded leaves than the wild-type strain Guy11 and the complemented strain ΔMosmi1/MoSMI1.,Y Wang 2024,2024,1 gene,Wang-2024-A novel MAP kinase-interacting prote,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23147,PHI:124866,UniProt,G4NH12,GenBank,EHA47522,,,70-15,SMI1 (MGG_03970),chromosome 6,,,MoOsm1; MoMps1,UniProt: Q9UV51; GenBank: AAF09475; UniProt: O13352; GenBank: AAC63682,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),CO39,,,Leaves,MAP kinase-interacting protein,,,mitogen-activated protein kinase (MAPK) signalling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39034619,PubMed,10.1111/mpp.13493,Mol Plant Pathol. 2024 Jul;25(7):e13493.,panyuemin2008@163.com,ΔMosmi1 mutant caused more restricted lesions in both intact and wounded leaves than the wild-type strain Guy11 and the complemented strain ΔMosmi1/MoSMI1.,Y Wang 2024,2024,1 gene,Wang-2024-A novel MAP kinase-interacting prote,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23148,PHI:124867,UniProt,A0A2I2G4U7,GenBank,PLB47898,,,IBT 23096,CreA (XP_024703200.1),,,,,,,40380,Aspergillus ochraceus,,,,monocot,4498,Avena sativa (related: oat),,,,Seed,carbon catabolite repression gene,,,,reduced virulence,,,,,less infection,reduced,,reduced ; defective,reduced,no,,,,,,,gene deletion: full,,,NN,33152993,PubMed,10.3390/toxins12110697,Toxins (Basel). 2020 Nov 3;12(11):697.,xingfuguo@caas.cn,ΔAoCreA showed a significant growth and conidiation and pathogenecity defect.,G Wang 2020,2020,1 gene,Wang-2020-Carbon Catabolite Repression Gene Ao,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23149,PHI:124867,UniProt,A0A2I2G4U7,GenBank,PLB47898,,,IBT 23096,CreA (XP_024703200.1),,,,,,,40380,Aspergillus ochraceus,,,,eudicots,23211,Pyrus communis (related: pear),,,,fruit,carbon catabolite repression gene,,,,reduced virulence,,,,,less infection,reduced,,reduced ; defective,reduced,no,,,,,,,gene deletion: full,,,NN,33152993,PubMed,10.3390/toxins12110697,Toxins (Basel). 2020 Nov 3;12(11):697.,xingfuguo@caas.cn,ΔAoCreA showed a significant growth and conidiation and pathogenecity defect.,G Wang 2020,2020,1 gene,Wang-2020-Carbon Catabolite Repression Gene Ao,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23150,PHI:124868,UniProt,G2WW80,GenBank,EGY19850,,,VdLs.17,xyL3 (VDAG_01866),chromosome 7,,,,,,27337,Verticillium dahliae,,Vd592,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),Xinluzao 7,,,Seedlings; stem,xylosidase-encoding gene,,,,increased virulence (hypervirulence),,,,,high disease severity,increased,,increased,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39104581,PubMed,10.3389/fmicb.2024.1428780,Front Microbiol. 2024 Jul 22;15:1428780.,sunjie@shzu.edu.cn,"Deleting VdxyL3 led to increased colony expansion rate, conidial production, mycelial growth and pathogenicity of V. dahliae.",Y Li 2024,2024,1 gene,Li-2024-Deleting an xylosidase-encoding gene V,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23151,PHI:124869,UniProt,A0A0F7S9J4,GenBank,CDS82158,,,SscI8,Cyp86,,,,,,,49012,Sporisorium scitamineum,,MAT-1 x MAT-2,sugarcane smut,monocots,4547,Saccharum officinarum (related: sugarcane),,,,Seedling,cytochrome P450,,,beta-oxidation pathway,reduced virulence,,,,,less symptoms,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,39177034,PubMed,10.1080/21505594.2024.2395833,Virulence. 2024 Dec;15(1):2395833.,changcq@scau.edu.cn,"Compared to the wild-type (MAT-1 × MAT-2), the SsCYP86 deletion mutant (sscyp86Δ-1 × sscyp86Δ-2) showed a significant reduction in the typical whip symptoms in sugarcane seedlings, with only 7.6% disease incidence.",E Cai 2024,2024,1 gene,Cai-2024-SsCyp86 modulates sporisorium scitami,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23152,PHI:124870,UniProt,A0A7G9P5W1,GenBank,QNN25949,,,,cmcp,,,,,,,929235,Ceratocystis manginecans,,MG-1-10,mango wilt,eudicot,29780,Mangifera indica (related: mango),,,,Branches,CP protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32849428,PubMed,10.3389/fmicb.2020.01824,Front Microbiol. 2020 Jul 31;11:1824.,lijq231@cau.edu.cn,"Δcmcp showed reduced morphology, mycelial growth, conidial production and pathogenicity compared to wild type.",Z Zhang 2020,2020,1 gene,Zhang-2020-Characterization of cmcp Gene as a,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23153,PHI:124871,UniProt,A0A9P5CQV5,GenBank,KAF3767598,,,EP155,MTA1 (XP_040778559),chromosome unknown,,,,,,5116,Cryphonectria parasitica,660469,EP155,chestnut blight,eudicots,60419,Castanea mollissima (related: chinese chestnut),,,,stem,m6 A methyltransferase,,,MAPK signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced ; defective,,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39159278,PubMed,10.1371/journal.ppat.1012476,PLoS Pathog. 2024 Aug 19;20(8):e1012476.,chenyaoj@gxu.edu.cn,A significant virulence reduction of the ΔCpMTA1 mutants. The ΔCpMTA1-com strain restored the virulence to resemble that of wild-type strains.,L Zhao 2024,2024,1 gene,Zhao-2024-N6-methyladenosine RNA methyltransfe,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23154,PHI:124871,UniProt,A0A9P5CQV5,GenBank,KAF3767598,,,EP155,MTA1 (XP_040778559),chromosome unknown,,,,,,5116,Cryphonectria parasitica,660469,EP155,chestnut blight,eudicots,3750,Malus domestica (related: apple),Fuji,,,stem,m6 A methyltransferase,,,MAPK signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced ; defective,,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39159278,PubMed,10.1371/journal.ppat.1012476,PLoS Pathog. 2024 Aug 19;20(8):e1012476.,chenyaoj@gxu.edu.cn,A significant virulence reduction of the ΔCpMTA1 mutants. The ΔCpMTA1-com strain restored the virulence to resemble that of wild-type strains.,L Zhao 2024,2024,1 gene,Zhao-2024-N6-methyladenosine RNA methyltransfe,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23155,PHI:124872,UniProt,Q0V2F7,GenBank,EAT91456,,,SN15,VeA (SNOG_01807),,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocot,4565,Triticum aestivum (related: bread wheat),Axe,,,Leaves,velvet transcription factor,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39127645,PubMed,10.1186/s12866-024-03454-7,BMC Microbiol. 2024 Aug 10;24(1):299.,Kar-Chun.Tan@curtin.edu.au,"Deletion of the PnVeA, resulted in growth abnormalities, abolished asexual sporulation and highly reduced virulence on wheat.",S Morikawa 2024,2024,1 gene,Morikawa-2024-The Velvet transcription factor,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23156,PHI:124873,UniProt,I1RZ36,GenBank,CEF83519,,,PH-1,Mdm33 (FGSG_09659),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Jimai33,,,Spikelets; Leaves,mitochondrial distribution and morphology family 33 gene,,,,reduced virulence,,,,,limited scab symptoms,reduced,,reduced,wild type,no,hydrogen peroxide (H2O2);paraquat;glucose,hydrogen peroxide (H2O2): CHEBI:16240; ;paraquat: CHEBI:34905; ;glucose: CHEBI:17234,,,,,gene deletion: full ; gene complementation,,,NN,39194905,PubMed,10.3390/jof10080579,J Fungi (Basel). 2024 Aug 16;10(8):579.,lvwy@zafu.edu.cn,ΔFgmdm33-3 and ΔFgmdm33-5 mutants triggered slight scab symptoms compared to wild type.,W Lv 2024,2024,1 gene,Lv-2024-The Mitochondrial Distribution and Mor,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23157,PHI:124874,UniProt,G2WZ61,GenBank,EGY21863,,,VdLs.17,Nop12 (VDAG_03303),chromosome 6,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),Junmian No.1,,,Seedlings; stem,RNA binding protein,,,cAMP-PKA and MAPK pathway,reduced virulence,,,yes,,low disease severity,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33000558,PubMed,10.1111/1462-2920.15268,Environ Microbiol. 2020 Dec;22(12):5387-5401.,guowei01@caas.cn,"Mutants produced by disruption of VdNop12 showed reduced defects in vegetative growth, conidiation and virulence.",J Zhang 2020,2020,1 gene,"Zhang-2020-VdNop12, containing two tandem RNA",BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23158,PHI:124875,UniProt,A0A6G6CU69,GenBank,QIE06315,,,,NOX2 (MN205394),,,,,,,5503,Curvularia lunata,1263492,CX-3,Curvularia leaf spot,monocot,4577,Zea mays (related: maize),,,,Leaves,NADPH oxidase,,,signalling pathway,reduced virulence,,,,,fewer lesions,increased,increased,increased,increased,no,hydrogen peroxide (H2O2);NaCl;menadione;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,32815478,PubMed,10.1094/MPMI-06-20-0138-R,Mol Plant Microbe Interact. 2020 Nov;33(11):1315-1329.,chunshengxue@syau.edu.cn,The ΔClnox2 and ΔClbrn1 mutants induced fewer necrotic lesions compared with the WT and complemented strains at 6 dpi.,F Wang 2020,2020,2 genes,Wang-2020-NADPH Oxidase ClNOX2 Regulates Melan,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23159,PHI:124876,UniProt,Q2HZG9,GenBank,ABC86900,,,,BRN1 (ABC86900),,,,,,,5503,Curvularia lunata,1263492,CX-3,Curvularia leaf spot,monocot,4577,Zea mays (related: maize),,,,Leaves,brn1 protein,,,,reduced virulence,,,,,fewer lesions,increased,increased,increased,increased,no,hydrogen peroxide (H2O2);NaCl;menadione;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;menadione: CHEBI:28869; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,32815478,PubMed,10.1094/MPMI-06-20-0138-R,Mol Plant Microbe Interact. 2020 Nov;33(11):1315-1329.,chunshengxue@syau.edu.cn,The ΔClnox2 and ΔClbrn1 mutants induced fewer necrotic lesions compared with the WT and complemented strains at 6 dpi.,F Wang 2020,2020,2 genes,Wang-2020-NADPH Oxidase ClNOX2 Regulates Melan,BATCH_137,2024-09-01,MC,,,,,,,,,,,,,
,,Record 23160,PHI:124877,UniProt,A0A180GHN3,GenBank,OAV91938,,,1-1 BBBD Race 1,Pt9029 (OAV91938.1),,,,,,,208348,Puccinia triticina,,,wheat leaf rust,monocots,4565,Triticum aestivum (related: bread wheat),Zhengzhou 5389,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,39290056,PubMed,10.1111/nph.20142,New Phytol. 2024 Sep 17. doi: 10.1111/nph.20142. Online ahead of print,wenxiangyang2003@163.com,Infection area decreases after silencing Pt9029 by HIGS,J Chang 2024,2024,1 gene,Chang-2024-A thaumatin-like effector protein s,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23161,PHI:124877,UniProt,A0A180GHN3,GenBank,OAV91938,,,1-1 BBBD Race 1,Pt9029 (OAV91938.1),,,,,,,208348,Puccinia triticina,,,wheat leaf rust,monocots,4565,Triticum aestivum (related: bread wheat),Zhengzhou 5389,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39290056,PubMed,10.1111/nph.20142,New Phytol. 2024 Sep 17. doi: 10.1111/nph.20142. Online ahead of print,wenxiangyang2003@163.com,"Compared to control plants, the incubation phase of wheat leaf rust disease progression on the OE: Pt9029DSP was shortened by 2 d.",J Chang 2024,2024,1 gene,Chang-2024-A thaumatin-like effector protein s,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23162,PHI:124878,UniProt,A0A0B6RWS5,GenBank,AJK45500,,,PG1,plaI,chromosome 1,,,,,,41899,Burkholderia plantarii,,KACC18965,rice seedling blight,monocots,4530,Oryza sativa (related: rice),,,,Seedlings; Panicles,GNAT family N-acetyltransferase,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39339632,PubMed,10.3390/plants13182657,Plants (Basel). 2024 Sep 23;13(18):2657.,yseo2011@pusan.ac.kr,The plaI deletion mutant exhibited a slight reduction in virulence com pared to the wild type and complemented strain.,M Kang 2024,2024,1 gene,Kang-2024-Impact of Quorum Sensing on the Viru,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23163,PHI:124879,UniProt,G4N0Z0,GenBank,EHA52368,,,70-15,hg1,chromosome 3,,,MGG_00623,UniProt: G4NB55; GenBank: EHA48816,,318829,Magnaporthe oryzae,,YN125,rice blast,monocot,4530,Oryza sativa (related: rice),Lijiangxintuanheigu,,,leaves,hypha growth gene,,,MAPK and sugar metabolism pathways,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full,,,NN,39330422,PubMed,10.3390/jof10090663,J Fungi (Basel). 2024 Sep 21;10(9):663.,licheng_yun@163.com,ΔMohg1 mutants display compromised fungal development and pathogenicity compared with the wild type.,X Pu 2024,2024,1 gene,Pu-2024-MoHG1 Regulates Fungal Development and,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23164,PHI:124880,UniProt,G4ML01,GenBank,EHA58428,,,70-15,PARP (MGG_08613),chromosome 1,,,GRF1 (MGG_13806); GRF2 (MGG_01588),UniProt: G4MRU8; GenBank: EHA58313; UniProt: G4MTW6; GenBank: EHA54760,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,poly(ADP-ribose) polymerase 1,,,,reduced virulence,,,,,,reduced,,reduced,,no,sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39277621,PubMed,10.1038/s41467-024-51955-w,Nat Commun. 2024 Sep 14;15(1):8047.,wwlin@126.com,"Δparp1 strain caused significantly reduced disease symptoms (lesion numbers, sizes, and levels) compared to the wild type or complementation strains",X Gao 2024,2024,3 genes,Gao-2024-PARylation of 14-3-3 proteins control,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23165,PHI:124881,UniProt,G4MRU8,GenBank,EHA58313,,,70-15,GRF1( MGG_13806),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,14-3-3 protein,,,DNA damage sensing pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39277621,PubMed,10.1038/s41467-024-51955-w,Nat Commun. 2024 Sep 14;15(1):8047.,wwlin@126.com,The 14-3-3 mutants developed significantly reduced disease symptoms compared to the wild type.,X Gao 2024,2024,3 genes,Gao-2024-PARylation of 14-3-3 proteins control,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23166,PHI:124882,UniProt,G4MTW6,GenBank,EHA54760,,,70-15,GRF2 ( MGG_01588),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,14-3-3 protein,,,DNA damage sensing pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39277621,PubMed,10.1038/s41467-024-51955-w,Nat Commun. 2024 Sep 14;15(1):8047.,wwlin@126.com,The 14-3-3 mutants developed significantly reduced disease symptoms compared to the wild type.,X Gao 2024,2024,3 genes,Gao-2024-PARylation of 14-3-3 proteins control,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23167,PHI:124881,UniProt,G4MRU8,GenBank,EHA58313,,,70-15,GRF1( MGG_13806),chromosome 1,"GRF1m3-5, GRF1m6-8, GRF1m9-11, GRF1m12-14, GRF1m15-17, GRF1m18-20, GRF1m21-23,",,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,14-3-3 protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene mutation,,,NN,39277621,PubMed,10.1038/s41467-024-51955-w,Nat Commun. 2024 Sep 14;15(1):8047.,wwlin@126.com,The GRF1 PARylation sites mutants developed significantly reduced disease symptoms compared to the wild type.,X Gao 2024,2024,3 genes,Gao-2024-PARylation of 14-3-3 proteins control,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23168,PHI:124883,UniProt,A0A0K0GF67,GenBank,ACD56681,,,PXO99A,PXO_03470,,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocot,4530,Oryza sativa (related: rice),,,,leaves,cardiolipin synthase,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39339552,PubMed,10.3390/plants13182576,Plants (Basel). 2024 Sep 14;13(18):2576.,aifangz@163.com,"Compared with the wild type strain PXO99A, the lesion length of the ΔPXO_03470 culture decreased significantly.",Y Hu 2024,2024,1 gene,Hu-2024-Strain of Xanthomonas oryzae pv. oryza,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23169,PHI:124884,UniProt,G2XER2,GenBank,EGY18313,,,VdLs.17,KeR1 (VDAG_08647),chromosome 2,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),Junmian 1,,,Seedlings; stem,Kelch repeat protein,,,ergosterol synthesis pathway,reduced virulence,,,yes,,low disease severity,reduced,reduced,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);terbinafine;Congo red;calcofluor white (CFW);calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;terbinafine: CHEBI:9448; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39330403,PubMed,10.3390/jof10090643,J Fungi (Basel). 2024 Sep 9;10(9):643.,cfengmao@njfu.edu.cn,Disease index statistics for cotton and maple showed that the incidence rate and incidence degree of the ΔVdKeR1 strains were significantly lower than those of the WT and EC_VdKeR1 strains.,W L Xia 2024,2024,1 gene,Xia-2024-The Kelch Repeat Protein VdKeR1 Is Es,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23170,PHI:124884,UniProt,G2XER2,GenBank,EGY18313,,,VdLs.17,KeR1 (VDAG_08647),chromosome 2,,,,,,27337,Verticillium dahliae,498257,VdLs.17,vascular wilt,eudicot,47965,Acer truncatum (related: maple),,,,Seedlings; stem,Kelch repeat protein,,,ergosterol synthesis pathway,reduced virulence,,,yes,,low disease severity,reduced,reduced,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);terbinafine;Congo red;calcofluor white (CFW);calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;terbinafine: CHEBI:9448; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39330403,PubMed,10.3390/jof10090643,J Fungi (Basel). 2024 Sep 9;10(9):643.,cfengmao@njfu.edu.cn,Disease index statistics for cotton and maple showed that the incidence rate and incidence degree of the ΔVdKeR1 strains were significantly lower than those of the WT and EC_VdKeR1 strains.,W L Xia 2024,2024,1 gene,Xia-2024-The Kelch Repeat Protein VdKeR1 Is Es,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23171,PHI:124885,UniProt,A0A384JLN3,GenBank,ATZ51402,,,B05.10,SAS2 (BC1G_05395),chromosome BCIN07,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicot,4081,Solanum lycopersicum (related: tomato),,,,Leaves,histone H4K16 acetyltransferasease,,,,reduced virulence,,,yes,,primary lesion,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,32689887,PubMed,10.1094/MPMI-06-20-0149-R,Mol Plant Microbe Interact. 2020 Oct;33(10):1242-1251.,wliang 1@qau.edu.cn,BcSas2 mutant showed primary lesions compared to both wild type and complemented strain.,G Wang 2020,2020,3 genes,Wang-2020-BcSas2-Mediated Histone H4K16 Acetyl,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23172,PHI:124886,UniProt,A0A384K1T7,GenBank,ATZ56497,,,B05.10,XYGA (BC1G_04913),chromosome BCIN13,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicot,4081,Solanum lycopersicum (related: tomato),,,,Leaves,glycoside hydrolase,,,,reduced virulence,,,yes,,smaller lesions,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,32689887,PubMed,10.1094/MPMI-06-20-0149-R,Mol Plant Microbe Interact. 2020 Oct;33(10):1242-1251.,wliang 1@qau.edu.cn,BcXYGA mutant showed greatly reduced lesions compared to both wild type and complemented strain.,G Wang 2020,2020,3 genes,Wang-2020-BcSas2-Mediated Histone H4K16 Acetyl,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23173,PHI:124887,UniProt,A0A384JT10,GenBank,ATZ53632,,,B05.10,CAT (BC1G_12146),chromosome BCIN09,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicot,4081,Solanum lycopersicum (related: tomato),,,,Leaves,catalase,,,,reduced virulence,,,yes,,smaller lesions,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,32689887,PubMed,10.1094/MPMI-06-20-0149-R,Mol Plant Microbe Interact. 2020 Oct;33(10):1242-1251.,wliang 1@qau.edu.cn,BcCAT mutant showed greatly reduced lesions compared to both wild type and complemented strain.,G Wang 2020,2020,3 genes,Wang-2020-BcSas2-Mediated Histone H4K16 Acetyl,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23174,PHI:124888,UniProt,G4MPR1,GenBank,EHA57208,,,70-15,Hrd1 (MGG_09205),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,E3 ubiquitin transferase,,,,reduced virulence,,,no,,smaller lesions,wild type,,wild type,,no,tunicamycin;dithiothreitol (DTT),tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full ; gene complementation,,,NN,32410295,PubMed,10.1111/1462-2920.15069,Environ Microbiol. 2020 Dec;22(12):4953-4973.,wangzh@fafu.edu.cn,"ΔMohrd1 mutant still caused disease lesions, but a significant reduction in lesion number was found compared with those produced by the WT and complemented strains.",W Tang 2020,2020,2 genes,Tang-2020-Endoplasmic reticulum-associated deg,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23175,PHI:124888,UniProt,G4MPR1,GenBank,EHA57208,,,70-15,Hrd1 (MGG_09205),chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),Golden promise,,,Leaves,E3 ubiquitin transferase,,,,reduced virulence,,,no,,smaller lesions,wild type,,wild type,,no,tunicamycin;dithiothreitol (DTT),tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full ; gene complementation,,,NN,32410295,PubMed,10.1111/1462-2920.15069,Environ Microbiol. 2020 Dec;22(12):4953-4973.,wangzh@fafu.edu.cn,"ΔMohrd1 mutant still caused disease lesions, but a significant reduction in lesion number was found compared with those produced by the WT and complemented strains.",W Tang 2020,2020,2 genes,Tang-2020-Endoplasmic reticulum-associated deg,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23176,PHI:124889,UniProt,G4N794,GenBank,EHA50804,,,70-15,Der1 (MGG_06444),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,Derlin,,,,loss of pathogenicity,,,no,,no lesion,wild type,,wild type,,no,tunicamycin;dithiothreitol (DTT),tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full ; gene complementation,,,NN,32410295,PubMed,10.1111/1462-2920.15069,Environ Microbiol. 2020 Dec;22(12):4953-4973.,wangzh@fafu.edu.cn,The ΔModer1 mutant had no significant effect on pathogenicity.,W Tang 2020,2020,2 genes,Tang-2020-Endoplasmic reticulum-associated deg,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23177,PHI:124889,UniProt,G4N794,GenBank,EHA50804,,,70-15,Der1 (MGG_06444),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),Golden promise,,,Leaves,Derlin,,,,loss of pathogenicity,,,no,,no lesion,wild type,,wild type,,no,tunicamycin;dithiothreitol (DTT),tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full ; gene complementation,,,NN,32410295,PubMed,10.1111/1462-2920.15069,Environ Microbiol. 2020 Dec;22(12):4953-4973.,wangzh@fafu.edu.cn,The ΔModer1 mutant had no significant effect on pathogenicity.,W Tang 2020,2020,2 genes,Tang-2020-Endoplasmic reticulum-associated deg,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23178,PHI:124888,UniProt,G4MPR1,GenBank,EHA57208,,,70-15,Hrd1 (MGG_09205),chromosome 1,,,,,PHI:124889,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,E3 ubiquitin transferase,,,,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,,no,tunicamycin;dithiothreitol (DTT),tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full,,,NN,32410295,PubMed,10.1111/1462-2920.15069,Environ Microbiol. 2020 Dec;22(12):4953-4973.,wangzh@fafu.edu.cn,No lesions were observed upon the leaves sprayed with conidia of the double gene deletion mutant ΔMohrd1ΔModer1.,W Tang 2020,2020,2 genes,Tang-2020-Endoplasmic reticulum-associated deg,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23179,PHI:124889,UniProt,G4N794,GenBank,EHA50804,,,70-15,Der1 (MGG_06444),chromosome 4,,,,,PHI:124888,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,Derlin,,,,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,,no,tunicamycin;dithiothreitol (DTT),tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full,,,NN,32410295,PubMed,10.1111/1462-2920.15069,Environ Microbiol. 2020 Dec;22(12):4953-4973.,wangzh@fafu.edu.cn,No lesions were observed upon the leaves sprayed with conidia of the double gene deletion mutant ΔMohrd1ΔModer1.,W Tang 2020,2020,2 genes,Tang-2020-Endoplasmic reticulum-associated deg,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23180,PHI:124888,UniProt,G4MPR1,GenBank,EHA57208,,,70-15,Hrd1 (MGG_09205),chromosome 1,,,,,PHI:124889,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),Golden promise,,,Leaves,E3 ubiquitin transferase,,,,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,,no,tunicamycin;dithiothreitol (DTT),tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full,,,NN,32410295,PubMed,10.1111/1462-2920.15069,Environ Microbiol. 2020 Dec;22(12):4953-4973.,wangzh@fafu.edu.cn,No lesions were observed upon the leaves sprayed with conidia of the double gene deletion mutant ΔMohrd1ΔModer1.,W Tang 2020,2020,2 genes,Tang-2020-Endoplasmic reticulum-associated deg,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23181,PHI:124889,UniProt,G4N794,GenBank,EHA50804,,,70-15,Der1 (MGG_06444),chromosome 4,,,,,PHI:124888,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),Golden promise,,,Leaves,Derlin,,,,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,,no,tunicamycin;dithiothreitol (DTT),tunicamycin: CHEBI:29699; ;dithiothreitol (DTT): CHEBI:42170,,,,,gene deletion: full,,,NN,32410295,PubMed,10.1111/1462-2920.15069,Environ Microbiol. 2020 Dec;22(12):4953-4973.,wangzh@fafu.edu.cn,No lesions were observed upon the leaves sprayed with conidia of the double gene deletion mutant ΔMohrd1ΔModer1.,W Tang 2020,2020,2 genes,Tang-2020-Endoplasmic reticulum-associated deg,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23182,PHI:124890,UniProt,Q8XVU1,GenBank,CAD16443,,,GMI1000,phcS,,,,,,,1310165,Ralstonia pseudosolanacearum,,OE1-1,bacterial wilt disease,eudicot,4081,Solanum lycopersicum (related: tomato),Ohgata-Fukuju,,,Seedlings,histidine kinase,,,,reduced virulence,,,,,low disease severity,,,increased,,no,,,,,,,gene deletion: full,,,NN,39295141,PubMed,10.1094/MPMI-05-24-0049-R,Mol Plant Microbe Interact. 2024 Sep;37(9):688-697.,yhikichi@kochi-u.ac.jp,phcS mutant was less virulent than the strain OE1-1.,W Senuma 2024,2024,2 genes,Senuma-2024-Contribution of the Sensor Histidi,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23183,PHI:124891,UniProt,Q8Y2P6,GenBank,CAD13817,,,GMI1000,vsrA,,,,,,,1310165,Ralstonia pseudosolanacearum,,OE1-1,bacterial wilt disease,eudicot,4081,Solanum lycopersicum (related: tomato),Ohgata-Fukuju,,,Seedlings,transmembrane sensor kinase,,,,reduced virulence,,,,,low disease severity,,,increased,,no,,,,,,,gene deletion: full,,,NN,39295141,PubMed,10.1094/MPMI-05-24-0049-R,Mol Plant Microbe Interact. 2024 Sep;37(9):688-697.,yhikichi@kochi-u.ac.jp,vsrA mutant was less virulent than the strain OE1-1.,W Senuma 2024,2024,2 genes,Senuma-2024-Contribution of the Sensor Histidi,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23184,PHI:124890,UniProt,Q8XVU1,GenBank,CAD16443,,,GMI1000,phcS,,,,,,PHI:124891,1310165,Ralstonia pseudosolanacearum,,OE1-1,bacterial wilt disease,eudicot,4081,Solanum lycopersicum (related: tomato),Ohgata-Fukuju,,,Seedlings,histidine kinase,,,,loss of pathogenicity,,,,,no lesion,,,increased,,no,,,,,,,gene deletion: full,,,NN,39295141,PubMed,10.1094/MPMI-05-24-0049-R,Mol Plant Microbe Interact. 2024 Sep;37(9):688-697.,yhikichi@kochi-u.ac.jp,phcS/vsrA double mutant did not show any wilt symptom 5 and 10 DAI.,W Senuma 2024,2024,2 genes,Senuma-2024-Contribution of the Sensor Histidi,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23185,PHI:124891,UniProt,Q8Y2P6,GenBank,CAD13817,,,GMI1000,vsrA,,,,,,PHI:124890,1310165,Ralstonia pseudosolanacearum,,OE1-1,bacterial wilt disease,eudicot,4081,Solanum lycopersicum (related: tomato),Ohgata-Fukuju,,,Seedlings,transmembrane sensor kinase,,,,loss of pathogenicity,,,,,no lesion,,,increased,,no,,,,,,,gene deletion: full,,,NN,39295141,PubMed,10.1094/MPMI-05-24-0049-R,Mol Plant Microbe Interact. 2024 Sep;37(9):688-697.,yhikichi@kochi-u.ac.jp,phcS/vsrA double mutant did not show any wilt symptom 5 and 10 DAI.,W Senuma 2024,2024,2 genes,Senuma-2024-Contribution of the Sensor Histidi,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23186,PHI:124890,UniProt,Q8XVU1,GenBank,CAD16443,,,GMI1000,phcS,,histidine to glutamine at amino acid position 230 in PhcS,,,,,1310165,Ralstonia pseudosolanacearum,,OE1-1,bacterial wilt disease,eudicot,4081,Solanum lycopersicum (related: tomato),Ohgata-Fukuju,,,Seedlings,histidine kinase,,,,loss of pathogenicity,,,,,no lesion,,,increased,,no,,,,,,,gene mutation,,,NN,39295141,PubMed,10.1094/MPMI-05-24-0049-R,Mol Plant Microbe Interact. 2024 Sep;37(9):688-697.,yhikichi@kochi-u.ac.jp,PhcS-H230Q mutant did not show any wilt symptom 5 and 10 DAI.,W Senuma 2024,2024,2 genes,Senuma-2024-Contribution of the Sensor Histidi,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23187,PHI:124891,UniProt,Q8Y2P6,GenBank,CAD13817,,,GMI1000,vsrA,,histidine to glutamine at amino acid position 256 in VsrA,,,,,1310165,Ralstonia pseudosolanacearum,,OE1-1,bacterial wilt disease,eudicot,4081,Solanum lycopersicum (related: tomato),Ohgata-Fukuju,,,Seedlings,transmembrane sensor kinase,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene mutation,,,NN,39295141,PubMed,10.1094/MPMI-05-24-0049-R,Mol Plant Microbe Interact. 2024 Sep;37(9):688-697.,yhikichi@kochi-u.ac.jp,VsrA-H256Q mutant showed same as strain OE1-1.,W Senuma 2024,2024,2 genes,Senuma-2024-Contribution of the Sensor Histidi,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23188,PHI:124892,UniProt,C6XGX7,GenBank,ACT57630,,,psy62,SDE19 (CLIBASIA_05320),,,,,,,34021,Candidatus Liberibacter asiaticus,,,huanglongbing,eudicots,2711,Citrus sinensis (related: sweet orange),Carrizo,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39255299,PubMed,10.1371/journal.ppat.1012542,PLoS Pathog. 2024 Sep 10;20(9):e1012542.,huangguiyan@gnnu.edu.cn,Bacterial populationd in SDE19 transgenic citrus lines was significantly higher than that in WT.,G Huang 2024,2024,1 gene,"Huang-2024-SDE19, a SEC-dependent effector fro",BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23189,PHI:124892,UniProt,C6XGX7,GenBank,ACT57630,,,psy62,SDE19 (CLIBASIA_05320),,,,,,,34021,Candidatus Liberibacter asiaticus,,,huanglongbing,eudicots,3702,Arabidopsis thaliana (related: thale cress),,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39255299,PubMed,10.1371/journal.ppat.1012542,PLoS Pathog. 2024 Sep 10;20(9):e1012542.,huangguiyan@gnnu.edu.cn,Bacterial populationd in SDE19 transgenic arabidopsis lines was significantly higher than that in WT.,G Huang 2024,2024,1 gene,"Huang-2024-SDE19, a SEC-dependent effector fro",BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23190,PHI:124893,UniProt,A0A1D8H332,GenBank,AOT86938,,,,Kpp2,,,,,,,185366,Ustilago esculenta,,SG200,infection,monocot,58934,Zizania latifolia (related: Manchurian wild rice),,,,Leaves,mitogen-activated protein kinase,,,,increased virulence (hypervirulence),,,yes,,high disease severity,,,wild type,,no,hydrogen peroxide (H2O2);NaCl;Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,32582058,PubMed,10.3389/fmicb.2020.01053,Front Microbiol. 2020 Jun 9;11:1053.,13656686088@163.com,"SG2001kpp2:UeKpp2-6 and SG2001kpp2:Kpp2-3 strains appeared as fuzzy colonies in vitro and showed severe disease phenotypes after inoculation, comparable to those of SG200.",Y Zhang 2020,2020,1 gene,Zhang-2020-Functional Properties of the MAP Ki,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23191,PHI:124894,UniProt,A0A098DUI8,GenBank,,,,,PYC1 (FGSG_07075),,,,,,,5518,Fusarium graminearum,449239,Z-3639,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Eunpamil,,,Wheat head; Coleoptile,pyruvate carboxylase,,,,unaffected pathogenicity,,,no,,wild type,reduced,wild type,reduced,reduced,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full ; gene complementation,,,NN,39250495,PubMed,10.1371/journal.ppat.1012544,PLoS Pathog. 2024 Sep 9;20(9):e1012544.,rome73@snu.ac.kr,The ΔFgpyc1 mutants were not defective in the infection of wheat head and coleoptiles and caused similar disease symptoms as the wild-type strain.,S Shin 2024,2024,2 genes,Shin-2024-Oxaloacetate anaplerosis differently,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23192,PHI:124895,UniProt,A0A0J9WHE4,GenBank,KNA96636,,,4287,PYC1 (FOXG_01733),chromosome 5,,,,,,5507,Fusarium oxysporum,426428,4287,Fusarium wilt,eudicot,4565,Triticum aestivum (related: bread wheat),,,,Seedlings,pyruvate carboxylase,,,,reduced virulence,,,yes,,low disease severity,reduced,wild type,reduced,reduced,no,glucose,glucose: CHEBI:17234,,,,,gene deletion: full ; gene complementation,,,NN,39250495,PubMed,10.1371/journal.ppat.1012544,PLoS Pathog. 2024 Sep 9;20(9):e1012544.,rome73@snu.ac.kr,Wilt symptoms and plant mortality were significantly reduced in plants inoculated with the ΔFopyc1 mutant compared to wild type.,S Shin 2024,2024,2 genes,Shin-2024-Oxaloacetate anaplerosis differently,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23193,PHI:124896,UniProt,I1RZS5,GenBank,CEF75232,,,PH-1,Sso2 (FGSG_09928),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,t-SNARE protein,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,,no,hydrogen peroxide (H2O2);tebuconazole;benomyl;benzoxazolin-2-one (BOA),hydrogen peroxide (H2O2): CHEBI:16240; ;tebuconazole: CHEBI:81781; ;benomyl: CHEBI:3015; ;benzoxazolin-2-one (BOA) CAS no.: CAS:59-49-4,,,,,gene deletion: full,,,NN,32484730,PubMed,10.1094/MPMI-01-20-0012-R,Mol Plant Microbe Interact. 2020 Jul;33(7):888-901.,hckist@umn.edu,The Sso2 mutant was significantly reduced in symptoms compared with wild type.,S P Omara 2020,2020,2 genes,O'Mara-2020-The Fusarium graminearum t-SNARE S,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23194,PHI:124896,UniProt,I1RZS5,GenBank,CEF75232,,,PH-1,Sso2 (FGSG_09928),chromosome 1,,,,,PHI:124897,5518,Fusarium graminearum,229533,PH1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,t-SNARE protein,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,32484730,PubMed,10.1094/MPMI-01-20-0012-R,Mol Plant Microbe Interact. 2020 Jul;33(7):888-901.,hckist@umn.edu,Δabc1/Δsso2 mutant was significantly less virulent than wild type and the Δsso2 single mutant.,S P Omara 2020,2020,2 genes,O'Mara-2020-The Fusarium graminearum t-SNARE S,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23195,PHI:124897,UniProt,I1RL06,GenBank,ESU08505,,,PH-1; NRRL 31084,abc1 (FGSG_04580),chromosome 2,,,,,PHI:124896,5518,Fusarium graminearum,229533,PH1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Norm,,,Spikelets,ABC transporter 1,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full,,,NN,32484730,PubMed,10.1094/MPMI-01-20-0012-R,Mol Plant Microbe Interact. 2020 Jul;33(7):888-901.,hckist@umn.edu,Δabc1/Δsso2 mutant was significantly less virulent than wild type and the Δsso2 single mutant.,S P Omara 2020,2020,2 genes,O'Mara-2020-The Fusarium graminearum t-SNARE S,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23196,PHI:124898,UniProt,A0A7U2EQG5,GenBank,QRC91151,,,SN15,Pf2,chromosome 1,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocot,4565,Triticum aestivum (related: bread wheat),Halberd,,,Leaves,Zn2Cys6 transcription factor,,,regulatory pathway,loss of pathogenicity,,,,,no lesion,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,39312592,PubMed,10.1371/journal.ppat.1012536,PLoS Pathog. 2024 Sep 23;20(9):e1012536.,evan.john@curtin.edu.au,pf2ko showed loss of virulence compared to wild type.,E John 2024,2024,6 genes,John-2024-Regulatory insight for a Zn2Cys6 tra,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23197,PHI:124899,UniProt,Q0UXM4,GenBank,EAT88695,,,SN15,Pro1 (SNOG_03490),,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocot,4565,Triticum aestivum (related: bread wheat),Halberd,,,Leaves,Zn2Cys6 transcription factor,,,,increased virulence (hypervirulence),,,,,larger lesions,reduced,reduced,increased,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,39312592,PubMed,10.1371/journal.ppat.1012536,PLoS Pathog. 2024 Sep 23;20(9):e1012536.,evan.john@curtin.edu.au,pro1 ko mutant showed increased virulence compared to wild type.,E John 2024,2024,6 genes,John-2024-Regulatory insight for a Zn2Cys6 tra,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23198,PHI:124900,UniProt,Q0UUS8,GenBank,EAT88246,,,SN15,Ada1 (SNOG_04486),,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocot,4565,Triticum aestivum (related: bread wheat),Halberd,,,Leaves,Zn2Cys6 transcription factor,,,,reduced virulence,,,,,smaller lesions,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,39312592,PubMed,10.1371/journal.ppat.1012536,PLoS Pathog. 2024 Sep 23;20(9):e1012536.,evan.john@curtin.edu.au,Ada1 ko mutant showed reduced virulence compared to wild type.,E John 2024,2024,6 genes,John-2024-Regulatory insight for a Zn2Cys6 tra,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23199,PHI:124901,UniProt,Q0UYU7,GenBank,EAT89798,,,SN15,Ebr1 (SNOG_03067),,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocot,4565,Triticum aestivum (related: bread wheat),Halberd,,,Leaves,Zn2Cys6 transcription factor,,,,reduced virulence,,,,,smaller lesions,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,39312592,PubMed,10.1371/journal.ppat.1012536,PLoS Pathog. 2024 Sep 23;20(9):e1012536.,evan.john@curtin.edu.au,Ebr1 ko mutant showed reduced virulence compared to wild type.,E John 2024,2024,6 genes,John-2024-Regulatory insight for a Zn2Cys6 tra,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23200,PHI:124902,UniProt,Q0UI49,GenBank,EAT83733,,,SN15,SNOG_08565,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocot,4565,Triticum aestivum (related: bread wheat),Halberd,,,Leaves,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,wild type,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,39312592,PubMed,10.1371/journal.ppat.1012536,PLoS Pathog. 2024 Sep 23;20(9):e1012536.,evan.john@curtin.edu.au,No morphological or virulence defects for the 08565_KO mutant,E John 2024,2024,6 genes,John-2024-Regulatory insight for a Zn2Cys6 tra,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23201,PHI:124903,UniProt,Q0UJ27,GenBank,EAT84513,,,SN15,SNOG_08237,,,,,,,13684,Parastagonospora nodorum,321614,SN15,Septoria nodorum blotch,monocot,4565,Triticum aestivum (related: bread wheat),Halberd,,,Leaves,Zn2Cys6 transcription factor,,,,unaffected pathogenicity,,,,,wild type,wild type,wild type,wild type,,no,,,,,,,gene deletion: full,,,NN,39312592,PubMed,10.1371/journal.ppat.1012536,PLoS Pathog. 2024 Sep 23;20(9):e1012536.,evan.john@curtin.edu.au,No morphological or virulence defects for the 08237_KO mutant,E John 2024,2024,6 genes,John-2024-Regulatory insight for a Zn2Cys6 tra,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23202,PHI:124904,UniProt,I1RN36,GenBank,CEF88132,,,PH-1,Cdc25,chromosome 3,,,FgRas2 (FGSG_10889); FgSte11 (FGSG_05484),UniProt: I1S2A3; UniProt: A0A0E0SIZ6; GenBank: CEF86409,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,spikelet; Leaves; Corn silk,Ras GTPases,,,cAMP and MAPK signalling pathway,loss of pathogenicity,,,yes,,no lesion,reduced,reduced,reduced,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,32537857,PubMed,10.1111/1462-2920.15129,Environ Microbiol. 2020 Dec;22(12):5109-5124.,chenyun0927@zju.edu.cn,No visible disease was developed for the ΔFgcdc25 on inoculated spikelet under the same condition compared to wild type,A Chen 2020,2020,2 genes,Chen-2020-The RasGEF FgCdc25 regulates fungal,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23203,PHI:124905,UniProt,I1S2A3,GenBank,,,,,ras2,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,spikelet; Leaves; Corn silk,Ras GTPases,,,cAMP and MAPK signalling pathway,reduced virulence,,,yes,,smaller lesions,reduced,reduced,reduced,,no,Congo red,Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,32537857,PubMed,10.1111/1462-2920.15129,Environ Microbiol. 2020 Dec;22(12):5109-5124.,chenyun0927@zju.edu.cn,"The ΔFgras2 was able to colonize in the inoculated spikelet, but failed to spread to nearby spikelets.",A Chen 2020,2020,2 genes,Chen-2020-The RasGEF FgCdc25 regulates fungal,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23204,PHI:124904,UniProt,I1RN36,GenBank,CEF88132,,,PH-1,Cdc25,chromosome 3,FgCdc25ΔSH3,,FgRas2 (FGSG_10889); FgSte11 (FGSG_05484),UniProt: I1S2A3; UniProt: A0A0E0SIZ6; GenBank: CEF86409,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,spikelet; Leaves; Corn silk,Ras GTPases,,,cAMP and MAPK signalling pathway,unaffected pathogenicity,,,yes,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,32537857,PubMed,10.1111/1462-2920.15129,Environ Microbiol. 2020 Dec;22(12):5109-5124.,chenyun0927@zju.edu.cn,FgCdc25ΔSH3-GFP transformant showed no visible difference in growth and virulence when compared to the wildtype strain PH-1,A Chen 2020,2020,2 genes,Chen-2020-The RasGEF FgCdc25 regulates fungal,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23205,PHI:124904,UniProt,I1RN36,GenBank,CEF88132,,,PH-1,Cdc25,chromosome 3,FgCdc25ΔRasGEF_N; FgCdc25ΔRasGEF-,,FgRas2 (FGSG_10889); FgSte11 (FGSG_05484),UniProt: I1S2A3; UniProt: A0A0E0SIZ6; GenBank: CEF86409,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,spikelet; Leaves; Corn silk,Ras GTPases,,,cAMP and MAPK signalling pathway,loss of pathogenicity,,,yes,,wild type,,,reduced,,no,,,,,,,gene deletion: full,,,NN,32537857,PubMed,10.1111/1462-2920.15129,Environ Microbiol. 2020 Dec;22(12):5109-5124.,chenyun0927@zju.edu.cn,FgCdc25ΔRasGEF_NGFP and FgCdc25ΔRasGEF-GFP exhibited similar phenotypic defects in growth and virulence observed in ΔFgcdc25.,A Chen 2020,2020,2 genes,Chen-2020-The RasGEF FgCdc25 regulates fungal,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23206,PHI:124906,UniProt,A0A0K0MIQ0,GenBank,AKE48501,,,UVas1-58,mat 1-1-3 (AKE48501.1),,,,MAT1-1-1,,,1159556,Villosiclava virens,,Uv1-56,rice false smut,monocot,4530,Oryza sativa (related: rice),Liangyoupeijiu,,,Spikelets,mating-type gene,,,MAPK pathway,reduced virulence,,,,,false smut balls,increased,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,32714294,PubMed,10.3389/fmicb.2020.01337,Front Microbiol. 2020 Jun 25;11:1337.,liuyf@jaas.ac.cn,Rice panicles infected by the mat1-1-3 mutant produced significantly fewer false smut balls than those infected by WT and complemented C1mat1-1-3#16 strains.,M Yong 2020,2020,1 gene,"Yong-2020-MAT1-1-3, a Mating Type Gene in the",BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23207,PHI:124907,UniProt,G4NCV5,GenBank,EHA48348,,,70-15,Isw2 (MGG_01012),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Ku80,rice blast,monocot,4530,Oryza sativa (related: rice),,,,Leaves,regulatory protein,,,,loss of pathogenicity,,,,,no symptoms,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39292005,PubMed,10.1128/mbio.01590-24,mBio. 2024 Oct 16;15(10):e0159024.,Stefan@olssonstefan.com,ΔMoisw2 showed no infection compared to complemented strain and wild type.,M Pei 2024,2024,1 gene,Pei-2024-Whole genome regulatory effect of MoI,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23208,PHI:124907,UniProt,G4NCV5,GenBank,EHA48348,,,70-15,Isw2 (MGG_01012),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Ku80,rice blast,monocot,4513,Hordeum vulgare (related: barley),,,,Leaves,regulatory protein,,,,loss of pathogenicity,,,,,no symptoms,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39292005,PubMed,10.1128/mbio.01590-24,mBio. 2024 Oct 16;15(10):e0159024.,Stefan@olssonstefan.com,ΔMoisw2 showed no infection compared to complemented strain and wild type.,M Pei 2024,2024,1 gene,Pei-2024-Whole genome regulatory effect of MoI,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23209,PHI:124908,UniProt,A0A5N5DG02,GenBank,KAB2575894,,,LA-SOL3,EPG1,,,,,,,45133,Lasiodiplodia theobromae,,CSS-01,grapevine canker disease,eudicot,29760,Vitis vinifera (related: wine grape),Summer Black,,,Shoot,secretory endopolygalacturonase protein,,,KINβ1 mediated signal pathway,increased virulence (hypervirulence),,,,,larger lesions,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,32460690,PubMed,10.1094/PHYTO-04-20-0118-R,Phytopathology. 2020 Oct;110(10):1727-1736.,jiyeyan@vip.163.com,The overexpression transformants of LtEPG1 showed evidently elevated pathogenicity relative to that in the wild type.,K W Thilini Chethana 2020,2020,1 gene,"Thilini Chethan-2020-LtEPG1, a Secretory Endop",BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23210,PHI:124908,UniProt,A0A5N5DG02,GenBank,KAB2575894,,,LA-SOL3,EPG1,,,,,,,45133,Lasiodiplodia theobromae,,CSS-01,grapevine canker disease,eudicot,29760,Vitis vinifera (related: wine grape),Summer Black,,,Shoot,secretory endopolygalacturonase protein,,,KINβ1 mediated signal pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,32460690,PubMed,10.1094/PHYTO-04-20-0118-R,Phytopathology. 2020 Oct;110(10):1727-1736.,jiyeyan@vip.163.com,RNAi transformant of LtEPG1 exhibited significantly decreased pathogenicity in comparison with that in the wild type.,K W Thilini Chethana 2020,2020,1 gene,"Thilini Chethan-2020-LtEPG1, a Secretory Endop",BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23211,PHI:124909,UniProt,A0A0K0GGZ5,GenBank,ACD57493,,,PXO99A,HrrP (PXO_04157),,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocot,4530,Oryza sativa (related: rice),Nipponbare,,,Leaves,histidine kinase-response regular hybrid protein,,,,increased virulence (hypervirulence),,,,,larger lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32720873,PubMed,10.1094/MPMI-04-20-0088-R,Mol Plant Microbe Interact. 2020 Oct;33(10):1196-1208.,chenhuamin@caas.cn,hrrP mutant caused more severe disease symptoms and longer lesion length.,M U Shahbaz 2020,2020,7 genes,Shahbaz-2020-Identification of the Regulatory,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23212,PHI:124910,UniProt,A0A0K0GM11,GenBank,ACD59804,,,PXO99A,PhrP (PXO_01585),,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocot,4530,Oryza sativa (related: rice),Nipponbare,,,Leaves,PhoPQ-regulated protein,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32720873,PubMed,10.1094/MPMI-04-20-0088-R,Mol Plant Microbe Interact. 2020 Oct;33(10):1196-1208.,chenhuamin@caas.cn,phrP mutant caused same disease symptoms as wild type.,M U Shahbaz 2020,2020,7 genes,Shahbaz-2020-Identification of the Regulatory,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23213,PHI:124911,UniProt,A0A0K0GRJ7,GenBank,ACD61635,,,PXO99A,ProP (PXO_03510),,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocot,4530,Oryza sativa (related: rice),Nipponbare,,,Leaves,prophage lp2 protein 6,,,,increased virulence (hypervirulence),,,,,larger lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32720873,PubMed,10.1094/MPMI-04-20-0088-R,Mol Plant Microbe Interact. 2020 Oct;33(10):1196-1208.,chenhuamin@caas.cn,ProP mutant caused more severe disease symptoms and longer lesion length.,M U Shahbaz 2020,2020,7 genes,Shahbaz-2020-Identification of the Regulatory,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23214,PHI:124912,UniProt,A0A0K0GIG1,GenBank,ACD58006,,,PXO99A,cheW1 (PXO_04752),,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocot,4530,Oryza sativa (related: rice),Nipponbare,,,Leaves,chemotaxis protein,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32720873,PubMed,10.1094/MPMI-04-20-0088-R,Mol Plant Microbe Interact. 2020 Oct;33(10):1196-1208.,chenhuamin@caas.cn,cheW1 mutant caused less severe disease symptoms and shorter lesion length compared to wild type.,M U Shahbaz 2020,2020,7 genes,Shahbaz-2020-Identification of the Regulatory,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23215,PHI:124913,UniProt,A0A0K0GIC0,GenBank,ACD58005,,,PXO99A,EdpX2 (PXO_04753),,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocot,4530,Oryza sativa (related: rice),Nipponbare,,,Leaves,response regulator with EAL domain,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32720873,PubMed,10.1094/MPMI-04-20-0088-R,Mol Plant Microbe Interact. 2020 Oct;33(10):1196-1208.,chenhuamin@caas.cn,EdpX2 mutant caused same disease symptoms compared to wild type.,M U Shahbaz 2020,2020,7 genes,Shahbaz-2020-Identification of the Regulatory,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23216,PHI:124914,UniProt,A0A0K0GJX0,GenBank,ACD58485,,,PXO99A,HGdpX2 (PXO_00476),,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocot,4530,Oryza sativa (related: rice),Nipponbare,,,Leaves,two-component system regulatory protein with HD-GYP domain,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32720873,PubMed,10.1094/MPMI-04-20-0088-R,Mol Plant Microbe Interact. 2020 Oct;33(10):1196-1208.,chenhuamin@caas.cn,hGdpX2 mutant caused less severe disease symptoms and shorter lesion length compared to wild type.,M U Shahbaz 2020,2020,7 genes,Shahbaz-2020-Identification of the Regulatory,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23217,PHI:124915,UniProt,A0A0K0GMY4,GenBank,ACD60174,,,PXO99A,TdrX2 (PXO_01883),,,,,,,347,Xanthomonas oryzae,360094,PXO99,leaf blight,monocot,4530,Oryza sativa (related: rice),Nipponbare,,,Leaves,TonB-dependent receptor/oar-like,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32720873,PubMed,10.1094/MPMI-04-20-0088-R,Mol Plant Microbe Interact. 2020 Oct;33(10):1196-1208.,chenhuamin@caas.cn,tdrX2 mutant caused less severe disease symptoms and shorter lesion length compared to wild type.,M U Shahbaz 2020,2020,7 genes,Shahbaz-2020-Identification of the Regulatory,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23218,PHI:124916,UniProt,W7LYY0,GenBank,EWG40475,,,7600,stuA (FVEG_02853),chromosome 5,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocot,4577,Zea mays (related: maize),Silver Queen,,,Seedlings,regulator protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,32293993,PubMed,10.1094/MPMI-09-19-0271-R,Mol Plant Microbe Interact. 2020 Jul;33(7):958-971.,scott.gold@usda.gov,"FvstuA deletion mutant exhibited reduced vegetative growth, stunded aerial hyphae, and significant reductions in microconidiation and virulence.",M Rath 2020,2020,1 gene,Rath-2020-FvSTUA is a Key Regulator of Sporula,BATCH_138,2024-10-01,MC,,,,,,,,,,,,,
,,Record 23219,PHI:124917,UniProt,A0A8S9CQC0,GenBank,KAE9572566,,,CGMCC3.17371,Ap1,,,,,,,690256,Colletotrichum fructicola,,CFLH16,anthracnose,eudicot,385388,Camellia oleifera (related: tea-oil plant),,,,Leaves,transcription factor,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,39423133,PubMed,10.1080/21505594.2024.2413851,Virulence. 2024 Dec;15(1):2413851.,songsheng@csuft.edu.cn,"ΔCfap1 mutant was cause significantly smaller lesions, averaging 0.53 cm in diameter on fresh tea-oil leaves, after three days compared to wild type.",Y Gao 2024,2024,1 gene,39423133-Gao-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23220,PHI:124918,UniProt,A0A0D2Y2N0,GenBank,EGU84875,,,Fo5176,Tup1,,,,,,,5507,Fusarium oxysporum,,,Fusarium wilt,eudicot,265785,Atractylodes macrocephala,,,,root,dsRNA,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,39408614,PubMed,10.3390/ijms251910286,Int J Mol Sci. 2024 Sep 24;25(19):10286.,yuanxiaofeng@zcmu.edu.cn,dsRNA could reduce the virulence of F. oxysporum by silencing the Tup1 gene and effectively mitigate the root rot disease it causes in A. macrocephala.,S Fan 2024,2024,1 gene,39408614-Fan-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23221,PHI:124919,UniProt,I1RH76,GenBank,CEF77859,,,PH-1,Pel1 (FGSG_03121),chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,Corn silk; Wheat ears,pectin lyase gene,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,NN,39452618,PubMed,10.3390/jof10100666,J Fungi (Basel). 2024 Sep 24;10(10):666.,madf@yangtzeu.edu.cn,Deletion mutant significantly reduced the ability of F. graminearum to infest corn silks and wheat ears.,L Cai 2024,2024,3 genes,39452618-Cai-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23222,PHI:124920,UniProt,I1RZZ4,GenBank,CEF75329,,,PH-1,Pel2 (FGSG_10004),chromosome 1,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,Corn silk; Wheat ears,pectin lyase gene,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,NN,39452618,PubMed,10.3390/jof10100666,J Fungi (Basel). 2024 Sep 24;10(10):666.,madf@yangtzeu.edu.cn,Deletion mutant significantly reduced the ability of F. graminearum to infest corn silks and wheat ears.,L Cai 2024,2024,3 genes,39452618-Cai-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23223,PHI:124921,UniProt,I1SAF3,GenBank,CEF87943,,,PH-1,Pel3 (FGSG_13834),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,Corn silk; Wheat ears,pectin lyase gene,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,wild type,no,,,,,,,gene deletion: full,,,NN,39452618,PubMed,10.3390/jof10100666,J Fungi (Basel). 2024 Sep 24;10(10):666.,madf@yangtzeu.edu.cn,Deletion mutant significantly reduced the ability of F. graminearum to infest corn silks and wheat ears.,L Cai 2024,2024,3 genes,39452618-Cai-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23224,PHI:124922,UniProt,A0A0E0RZB4,GenBank,CEF76589,,,PH-1,M35,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Xiaoyan 22,,,Spikelets,zinc metalloprotease,,,,reduced virulence,,,,,smaller lesions,reduced,reduced,wild type,wild type,no,hydrogen peroxide (H2O2);CaCl2;NaCl;MgCl2;CuSO4;KCl;caffeine;sodium dodecyl sulphate (SDS);tebuconazole;phenamacril;Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;MgCl2: CHEBI:6636; ;CuSO4: CHEBI:23414; ;KCl: CHEBI:32588; ;caffeine: CHEBI:27732; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;tebuconazole: CHEBI:81781; ;phenamacril: CAS:3336-69-4; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39472326,PubMed,10.1007/s44154-024-00171-z,Stress Biol. 2024 Oct 30;4(1):45.,qiangli@nwsuaf.edu.cn,Deletion mutant ΔFgM35 affect sexual and asexual reproduction and reduced virulence.,X T Wang 2024,2024,1 gene,39472326-Wang-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23225,PHI:124922,UniProt,A0A0E0RZB4,GenBank,CEF76589,,,PH-1,M35,chromosome 2,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4577,Zea mays (related: maize),,,,Corn silk,zinc metalloprotease,,,,reduced virulence,,,,,smaller lesions,reduced,reduced,wild type,wild type,no,hydrogen peroxide (H2O2);CaCl2;NaCl;MgCl2;CuSO4;KCl;caffeine;sodium dodecyl sulphate (SDS);tebuconazole;phenamacril;Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;MgCl2: CHEBI:6636; ;CuSO4: CHEBI:23414; ;KCl: CHEBI:32588; ;caffeine: CHEBI:27732; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;tebuconazole: CHEBI:81781; ;phenamacril: CAS:3336-69-4; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39472326,PubMed,10.1007/s44154-024-00171-z,Stress Biol. 2024 Oct 30;4(1):45.,qiangli@nwsuaf.edu.cn,Deletion mutant ΔFgM35 affect sexual and asexual reproduction and reduced virulence.,X T Wang 2024,2024,1 gene,39472326-Wang-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23226,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH03,Fusarium head blight,eudicot,4113,Solanum tuberosum (related: potato),,,,tuber,ENNIATIN SYNTHASE 1,,,,reduced virulence,,,,,reduced necrosis,,,increased,wild type,no,,,,,,,gene deletion: full,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,Δesyn1 mutants of FaLH03 isolate resulted in reduced necrosis on tubers.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23227,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH27,Fusarium head blight,eudicot,4113,Solanum tuberosum (related: potato),,,,tuber,ENNIATIN SYNTHASE 1,,,,reduced virulence,,,,,reduced necrosis,,,wild type,increased,no,,,,,,,gene deletion: full,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,Δesyn1 mutants of FaLH27 isolate resulted in reduced necrosis on tubers.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23228,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH27,Fusarium head blight,eudicot,4113,Solanum tuberosum (related: potato),,,,tuber,ENNIATIN SYNTHASE 1,,,,increased virulence (hypervirulence),,,,,increased necrosis,,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,Overexpression esyn1 mutant of FaLH27 isolate resulted in increased necrosis on tubers.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23229,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH03,Fusarium head blight,monocot,4571,Triticum turgidum (related: durum wheat),Langdon,,,spikelet,ENNIATIN SYNTHASE 1,,,,unaffected pathogenicity,,,,,wild type,,,increased,wild type,no,,,,,,,gene deletion: full,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,No difference in disease aggressiveness is observed among the WT strains and the ESYN1 overexpression and disruption mutants.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23230,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH27,Fusarium head blight,monocot,4571,Triticum turgidum (related: durum wheat),Langdon,,,spikelet,ENNIATIN SYNTHASE 1,,,,unaffected pathogenicity,,,,,wild type,,,wild type,increased,no,,,,,,,gene deletion: full,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,No difference in aggressiveness is observed among the WT strains and the ESYN1 overexpression and disruption mutants.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23231,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH27,Fusarium head blight,monocot,4571,Triticum turgidum (related: durum wheat),Langdon,,,spikelet,ENNIATIN SYNTHASE 1,,,,unaffected pathogenicity,,,,,wild type,,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,No difference in aggressiveness is observed among the WT strains and the ESYN1 overexpression and disruption mutants.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23232,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH27,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Roblin,,,spikelet,ENNIATIN SYNTHASE 1,,,,unaffected pathogenicity,,,,,wild type,,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,No difference in aggressiveness is observed among the WT strains and the ESYN1 overexpression.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23233,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH03,Fusarium head blight,eudicot,3888,Pisum sativum (related: pea),Dakota; Meadow,,,Seed; root,ENNIATIN SYNTHASE 1,,,,unaffected pathogenicity,,,,,wild type,,,increased,wild type,no,,,,,,,gene deletion: full,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,There was no significant difference between percent emergence after inoculation with WT and derived mutant.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23234,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH27,Fusarium head blight,eudicot,3888,Pisum sativum (related: pea),Dakota,,,Seed,ENNIATIN SYNTHASE 1,,,,increased virulence (hypervirulence),,,,,increased necrosis,,,wild type,increased,no,,,,,,,gene deletion: full,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,"FaLH27Δesyn1_8, resulted in a significantly higher percent emergence compared to the WT, but it was not significantly different from the other mutants.",A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23235,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH27,Fusarium head blight,eudicot,3888,Pisum sativum (related: pea),Dakota,,,root,ENNIATIN SYNTHASE 1,,,,unaffected pathogenicity,,,,,wild type,,,wild type,increased,no,,,,,,,gene deletion: full,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,No difference in aggressiveness is observed among the WT strains and the ESYN1 overexpression and disruption mutants.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23236,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH27,Fusarium head blight,eudicot,3888,Pisum sativum (related: pea),Meadow,,,Seed; root,ENNIATIN SYNTHASE 1,,,,unaffected pathogenicity,,,,,wild type,,,wild type,increased,no,,,,,,,gene deletion: full,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,No difference in aggressiveness is observed among the WT strains and the ESYN1 overexpression and disruption mutants.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23237,PHI:124923,UniProt,A0A7S4ZE25,GenBank,QCC26563,,,,ESYN1,,,,,,,40199,Fusarium avenaceum,,LH27,Fusarium head blight,eudicot,3888,Pisum sativum (related: pea),Dakota; Meadow,,,Seed; root,ENNIATIN SYNTHASE 1,,,,unaffected pathogenicity,,,,,wild type,,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,31973184,PubMed,10.3390/pathogens9020075,Pathogens. 2020 Jan 21;9(2):75.,nora.foroud@canada.ca,No difference in aggressiveness is observed among the WT strains and the ESYN1 overexpression and disruption mutants.,A Eranthodi 2020,2020,1 gene,31973184-Eranthodi-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23238,PHI:124924,UniProt,A0A6M3RAS3,GenBank,QJD13448,,,,PKS12,,,,,,,38448,Monilinia fructicola,,Mf13-81,blossom blight and fruit rot,eudicot,3760,Prunus persica (related: peach),Tian Tao,,,fruit,polyketide synthase gene,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,32286920,PubMed,10.1094/PHYTO-02-20-0059-R,Phytopathology. 2020 Aug;110(8):1465-1475.,mhlee@nchu.edu.tw.,"LC2-17 displayed similar growth, sporulation, germination and less virulent.",F Y Yu 2020,2020,1 gene,32286920-Yu-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23239,PHI:124924,UniProt,A0A6M3RAS3,GenBank,QJD13448,,,,PKS12,,,,,,,38448,Monilinia fructicola,,Mf13-81,blossom blight and fruit rot,eudicot,323851,Prunus persica var. nucipersica (related: nectarines),Fantasy,,,fruit,polyketide synthase gene,,,,reduced virulence,,,,,smaller lesions,wild type,,wild type,wild type,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,32286920,PubMed,10.1094/PHYTO-02-20-0059-R,Phytopathology. 2020 Aug;110(8):1465-1475.,mhlee@nchu.edu.tw.,"LC2-17 displayed similar growth, sporulation, germination and less virulent.",F Y Yu 2020,2020,1 gene,32286920-Yu-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23240,PHI:124925,UniProt,A0A8E5HYF6,GenBank,QUC23685,,,UV-8b,Pfa4,chromosome 7,,,Slt2,UniProt: A0A063C378; GenBank: GAO17926,,1159556,Ustilaginoidea virens,,HWD-2,rice false smut disease,monocot,4530,Oryza sativa (related: rice),Wanxian-98,,,Panicle,palmitoyltransferases,,,,reduced virulence,,,,,smaller lesions,increased,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39470248,PubMed,10.1128/mbio.02704-24,mBio. 2024 Oct 29:e0270424.,junbinhuang@mail.hzau.edu.cn.,Virulence is significantly reduced in the UvPfa4 mutant.,Y Duan 2024,2024,3 genes,39470248-Duan-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23241,PHI:124926,UniProt,A0A8E5HUX4,GenBank,QUC22003,,,UV-8b,Swf1,chromosome 5,,,,,,1159556,Ustilaginoidea virens,,HWD-2,rice false smut disease,monocot,4530,Oryza sativa (related: rice),Wanxian-98,,,Panicle,palmitoyltransferases,,,,unaffected pathogenicity,,,,,wild type,increased,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39470248,PubMed,10.1128/mbio.02704-24,mBio. 2024 Oct 29:e0270424.,junbinhuang@mail.hzau.edu.cn.,Virulence is significantly same in the UvPfa4 mutant as wild type.,Y Duan 2024,2024,3 genes,39470248-Duan-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23242,PHI:124927,UniProt,A0A8E5HYF6,GenBank,GAO17926,,,IPU010,Slt2,,,,,,,1159556,Ustilaginoidea virens,,HWD-2,rice false smut disease,monocot,4530,Oryza sativa (related: rice),Wanxian-98,,,Panicle,palmitoyltransferases,,,,loss of pathogenicity,,,,,no lesion,increased,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39470248,PubMed,10.1128/mbio.02704-24,mBio. 2024 Oct 29:e0270424.,junbinhuang@mail.hzau.edu.cn.,Loss of virulence is seen in the UvSlt2 mutant.,Y Duan 2024,2024,3 genes,39470248-Duan-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23243,PHI:124927,UniProt,A0A8E5HYF6,GenBank,GAO17926,,,IPU010,Slt2,,UvSlt2C161A/C166A,,,,,1159556,Ustilaginoidea virens,,HWD-2,rice false smut disease,monocot,4530,Oryza sativa (related: rice),Wanxian-98,,,Panicle,palmitoyltransferases,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene mutation,,,NN,39470248,PubMed,10.1128/mbio.02704-24,mBio. 2024 Oct 29:e0270424.,junbinhuang@mail.hzau.edu.cn.,UvSlt2C161A/C166A strain showed significantly reduced sporulation and virulence.,Y Duan 2024,2024,3 genes,39470248-Duan-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23244,PHI:124928,UniProt,A0A0J9WIU9,GenBank,KNA99161,,,4287,Mac1 (FOXG_03227),chromosome 8,,,,,,5507,Fusarium oxysporum,426428,4287,Fusarium wilt,eudicots,4081,Solanum lycopersicum (related: tomato),Moneymaker,,,Seedlings,transcriptional regulator,,,,loss of pathogenicity,,,,,no disease,,,wild type,,no,CuSO4,CuSO4: CHEBI:23414,,,,,gene deletion: full ; gene complementation,,,NN,39495784,PubMed,10.1371/journal.ppat.1012671,PLoS Pathog. 2024 Nov 4;20(11):e1012671.,ge2dipia@uco.es,Plants inoculated with the wild-type or the complemented strain showed mortality rates close to 100% at 25 dpi whereas those inoculated with the mac1Δ mutant showed no visible disease symptoms.,R Palos-Fernández 2024,2024,1 gene,39495784-Palos-Fernandez-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23245,PHI:124929,UniProt,Q8Y0V3,GenBank,CAD14642,,,GMI1000,rsgA,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicot,4100,Nicotiana benthamiana (no common name found),,,,Seedlings; Leaves,small ribosomal subunit biogenesis GTPase,,,small ribosomal subunit biogenesis GTPase,loss of pathogenicity,,,,,no disease,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32240066,PubMed,10.1094/MPMI-10-19-0294-R,Mol Plant Microbe Interact. 2020 Jul;33(7):972-981.,bioyongzhang@swu.edu.cn,Compared to wild type both mutants failed to cause bacterial wilt disease in tobacco plants.,J Li 2020,2020,2 genes,32240066-Li-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23246,PHI:124930,UniProt,Q8XZV5,GenBank,CAD14992,,,GMI1000,rbfA,,,,,,,305,Ralstonia solanacearum,1429399,OE1-1,bacterial wilt,eudicot,4100,Nicotiana benthamiana (no common name found),,,,Seedlings; Leaves,ribosome-binding factor A,,,small ribosomal subunit biogenesis GTPase,loss of pathogenicity,,,,,no disease,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32240066,PubMed,10.1094/MPMI-10-19-0294-R,Mol Plant Microbe Interact. 2020 Jul;33(7):972-981.,bioyongzhang@swu.edu.cn,Compared to wild type both mutants failed to cause bacterial wilt disease in tobacco plants.,J Li 2020,2020,2 genes,32240066-Li-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23247,PHI:124931,UniProt,A0A098E2B1,GenBank,CEF88235,,,PH-1,UbiH (FGSG_11100),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,Spikelets,hydrolase,,,,reduced virulence,,,,,less symptoms,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);ethanol,hydrogen peroxide (H2O2): CHEBI:16240; ;ethanol: CHEBI:16236,,,,,gene deletion: full ; gene complementation,,,NN,39458403,PubMed,10.3390/microorganisms12102093,Microorganisms. 2024 Oct 20;12(10):2093.,huanchenzhai@126.com,"FgUbiH deletion mutant showed reduced hyphal growth, conidial production, germination, toxin synthesis, and pathogenicity compared to the wild-type.",J Ge 2024,2024,1 gene,39458403-Ge-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23248,PHI:124932,UniProt,D0N607,GenBank,EEY70498,,,T30-4,Pi05910,,,,,,,4787,Phytophthora infestans,,88069,late blight of potato,eudicot,4113,Solanum tuberosum (related: potato),Longshu 12,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,,,,,,no,,,,,,,functional test in host: transient expression,,,NN,39487604,PubMed,10.1111/mpp.70021,Mol Plant Pathol. 2024 Nov;25(11):e70021.,wxshan@nwafu.edu.cn,RXLR effector Pi05910 of P. infestans contributes virulence by suppressing and destabilizing host glycolate oxidase StGOX4.,P Zhang 2024,2024,1 gene,39487604-Zhang-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23249,PHI:124933,UniProt,G4NB56,GenBank,EHA48818,,,70-15,Ndt80 (MGG_00622),chromosome 5,,,"MoDac, MoDeam and MoHex",,,318829,Magnaporthe oryzae,,PLP-1,rice blast,monocot,4530,Oryza sativa (related: rice),Pusa Basmati-1,,,Leaves,transcriptional regulator,,,GlcNAc catabolic pathway,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32712567,PubMed,10.1016/j.micres.2020.126550,Microbiol Res. 2020 Oct;239:126550.,alka.narula@rediffmail.com,Disease symptoms revealed significant reduction of virulence in ΔMoNdt80 null mutant as compared to wild type.,D N Bhatt 2020,2020,1 gene,32712567-Bhatt-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23250,PHI:124934,UniProt,G4MY43,GenBank,EHA54374,,,70-15,Nsr1 (MGG_01268),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,nucleolin,,,,reduced virulence,,,,,fewer lesions,reduced,,reduced,,no,hydrogen peroxide (H2O2);methyl viologen;Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;methyl viologen: CHEBI:28786; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39494062,PubMed,10.3389/fpls.2024.1482934,Front Plant Sci. 2024 Oct 15;15:1482934.,wangjiaoyu78@sina.com,"MoNsr1 deletion mutant showed reduced fungal growth, asexual sporulation, and pathogenicity compared to the wild-type.",Z Zhang 2024,2024,1 gene,39494062-Zhang-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23251,PHI:124934,UniProt,G4MY43,GenBank,EHA54374,,,70-15,Nsr1 (MGG_01268),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),ZJ-8,,,Leaves,nucleolin,,,,reduced virulence,,,,,fewer lesions,reduced,,reduced,,no,hydrogen peroxide (H2O2);methyl viologen;Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;methyl viologen: CHEBI:28786; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39494062,PubMed,10.3389/fpls.2024.1482934,Front Plant Sci. 2024 Oct 15;15:1482934.,wangjiaoyu78@sina.com,"MoNsr1 deletion mutant showed reduced fungal growth, asexual sporulation, and pathogenicity compared to the wild-type.",Z Zhang 2024,2024,1 gene,39494062-Zhang-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23252,PHI:124935,UniProt,G2WWH6,GenBank,EGY19946,,,VdLs.17,epd1 (VDAG_01962),chromosome 7,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicot,3634,Gossypium barbadense (related: sea-island cotton),Hai7124,,,Seedling,secretory protein,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39488762,PubMed,10.1002/advs.202407787,Adv Sci (Weinh). 2024 Nov 3:e2407787.,zhangjie@im.ac.cn,"VdΔepd1 mutant, displayed enhanced virulence compared with the V592.",L Sun 2024,2024,2 genes,39488762-Sun-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23253,PHI:124936,UniProt,G2WWH5,GenBank,EGY19945,,,VdLs.17,01961 (VDAG_01961),chromosome 7,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicot,3634,Gossypium barbadense (related: sea-island cotton),Hai7124,,,Seedling,secretory protein,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39488762,PubMed,10.1002/advs.202407787,Adv Sci (Weinh). 2024 Nov 3:e2407787.,zhangjie@im.ac.cn,"VdΔ01961 mutant, did not enhanced virulence compared with the V592.",L Sun 2024,2024,2 genes,39488762-Sun-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23254,PHI:124937,UniProt,G2X5Z8,GenBank,EGY14150,,,VdLs.17,NPS (EGY14150),chromosome 2,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),,,,Seedling,nonribosomal peptide synthetase,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710,,,,,gene deletion: full ; gene complementation,,,NN,32228378,PubMed,10.1094/PHYTO-02-20-0031-R,Phytopathology. 2020 Aug;110(8):1398-1409.,luoxm@cqu.edu.cn,"Deletion of the NPS in verticillium dahliae led to the decrease of conidia, microsclerotia and pathogenicity.",X Luo 2020,2020,5 genes,32228378-Luo-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23255,PHI:124937,UniProt,G2X5Z8,GenBank,EGY14150,,,VdLs.17,NPS (EGY14150),chromosome 2,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicot,4100,Nicotiana benthamiana (no common name found),,,,Seedling,nonribosomal peptide synthetase,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);NaCl,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710,,,,,gene deletion: full ; gene complementation,,,NN,32228378,PubMed,10.1094/PHYTO-02-20-0031-R,Phytopathology. 2020 Aug;110(8):1398-1409.,luoxm@cqu.edu.cn,"Deletion of the NPS in verticillium dahliae led to the decrease of conidia, microsclerotia and pathogenicity.",X Luo 2020,2020,5 genes,32228378-Luo-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23256,PHI:124938,UniProt,G2X478,GenBank,EGY23522,,,VdLs.17,SAH1 (VDAG_04960),chromosome 4,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),,,,Seedling,salicylate hydroxylase,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32228378,PubMed,10.1094/PHYTO-02-20-0031-R,Phytopathology. 2020 Aug;110(8):1398-1409.,luoxm@cqu.edu.cn,Deletion of the VdSAH1 led to the decrease of pathogenicity compared to complemented strain and wild type.,X Luo 2020,2020,5 genes,32228378-Luo-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23257,PHI:124938,UniProt,G2X478,GenBank,EGY23522,,,VdLs.17,SAH1 (VDAG_04960),chromosome 4,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),,,,Seedling,salicylate hydroxylase,,,,increased virulence (hypervirulence),,,,,high disease severity,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,32228378,PubMed,10.1094/PHYTO-02-20-0031-R,Phytopathology. 2020 Aug;110(8):1398-1409.,luoxm@cqu.edu.cn,Overexpression of the VdSAH1 led to the increase of pathogenicity compared to complemented strain and wild type.,X Luo 2020,2020,5 genes,32228378-Luo-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23258,PHI:124939,UniProt,G2XAP9,GenBank,EGY16165,,,VdLs.17,SAH2 (VDAG_07329),chromosome 5,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),,,,Seedling,salicylate hydroxylase,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32228378,PubMed,10.1094/PHYTO-02-20-0031-R,Phytopathology. 2020 Aug;110(8):1398-1409.,luoxm@cqu.edu.cn,Deletion of the VdSAH2 led to the decrease of pathogenicity compared to complemented strain and wild type.,X Luo 2020,2020,5 genes,32228378-Luo-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23259,PHI:124939,UniProt,G2XAP9,GenBank,EGY16165,,,VdLs.17,SAH2 (VDAG_07329),chromosome 5,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),,,,Seedling,salicylate hydroxylase,,,,increased virulence (hypervirulence),,,,,high disease severity,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,32228378,PubMed,10.1094/PHYTO-02-20-0031-R,Phytopathology. 2020 Aug;110(8):1398-1409.,luoxm@cqu.edu.cn,Overexpression of the VdSAH2 led to the increase of pathogenicity compared to complemented strain and wild type.,X Luo 2020,2020,5 genes,32228378-Luo-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23260,PHI:124940,UniProt,G2XGN6,GenBank,EGY18984,,,VdLs.17,SAH3 (VDAG_09318),chromosome 4,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),,,,Seedling,salicylate hydroxylase,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32228378,PubMed,10.1094/PHYTO-02-20-0031-R,Phytopathology. 2020 Aug;110(8):1398-1409.,luoxm@cqu.edu.cn,Deletion of the VdSAH3 led to the decrease of pathogenicity compared to complemented strain and wild type.,X Luo 2020,2020,5 genes,32228378-Luo-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23261,PHI:124940,UniProt,G2XGN6,GenBank,EGY18984,,,VdLs.17,SAH3 (VDAG_09318),chromosome 4,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),,,,Seedling,salicylate hydroxylase,,,,increased virulence (hypervirulence),,,,,high disease severity,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,32228378,PubMed,10.1094/PHYTO-02-20-0031-R,Phytopathology. 2020 Aug;110(8):1398-1409.,luoxm@cqu.edu.cn,Overexpression of the VdSAH3 led to the increase of pathogenicity compared to complemented strain and wild type.,X Luo 2020,2020,5 genes,32228378-Luo-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23262,PHI:124941,UniProt,G2WWI2,GenBank,EGY19952,,,VdLs.17,SAH4 (VDAG_01968),chromosome 7,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),,,,Seedling,salicylate hydroxylase,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32228378,PubMed,10.1094/PHYTO-02-20-0031-R,Phytopathology. 2020 Aug;110(8):1398-1409.,luoxm@cqu.edu.cn,Deletion of the VdSAH4 led to the decrease of pathogenicity compared to complemented strain and wild type.,X Luo 2020,2020,5 genes,32228378-Luo-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23263,PHI:124941,UniProt,G2WWI2,GenBank,EGY19952,,,VdLs.17,SAH4 (VDAG_01968),chromosome 7,,,,,,27337,Verticillium dahliae,,V991,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),,,,Seedling,salicylate hydroxylase,,,,increased virulence (hypervirulence),,,,,high disease severity,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,32228378,PubMed,10.1094/PHYTO-02-20-0031-R,Phytopathology. 2020 Aug;110(8):1398-1409.,luoxm@cqu.edu.cn,Overexpression of the VdSAH4 led to the increase of pathogenicity compared to complemented strain and wild type.,X Luo 2020,2020,5 genes,32228378-Luo-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23264,PHI:124942,UniProt,B8N1D4,GenBank,QRD82697,,,NRRL 3357,SntB,chromosome 2,,,,,,5059,Aspergillus flavus,,Δku70 ΔpyrG,ear rot in corn and yellow mold in peanuts,eudicot,3818,Arachis hypogaea (related: peanut),,,,Seeds,transcriptional regulator,,,,reduced virulence,,,,,less infection,reduced,reduced,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39499647,PubMed,10.7554/eLife.94743,Elife. 2024 Nov 5;13:RP94743.,13635287532@163.com,"SntB reduced mycelia growth, conidial production, sclerotia formation, aflatoxin synthesis, and host colonization.",D Wu 2024,2024,1 gene,39499647-Wu-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23265,PHI:124942,UniProt,B8N1D4,GenBank,QRD82697,,,NRRL 3357,SntB,chromosome 2,,,,,,5059,Aspergillus flavus,,Δku70 ΔpyrG,ear rot in corn and yellow mold in peanuts,eudicot,4577,Zea mays (related: maize),,,,Kernels,transcriptional regulator,,,,reduced virulence,,,,,less infection,reduced,reduced,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39499647,PubMed,10.7554/eLife.94743,Elife. 2024 Nov 5;13:RP94743.,13635287532@163.com,"SntB reduced mycelia growth, conidial production, sclerotia formation, aflatoxin synthesis, and host colonization.",D Wu 2024,2024,1 gene,39499647-Wu-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23266,PHI:124943,UniProt,A0A0S4XD76,GenBank,AXV83243,,,T98,cspD3,,,,,,,305,Ralstonia solanacearum,,CQPS-1,bacterial wilt,eudicots,4100,Nicotiana benthamiana (no common name found),Yunyan 87,,,,cold shock family gene,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32088390,PubMed,10.1016/j.micpath.2020.104091,Microb Pathog. 2020 Feb 20;142:104091.,dingw@swu.edu.cn,The disease index of the ΔcspD3 mutant on the 20th day after inoculation was 1.6-fold reduced compared with the wild-type strain.,Y Liu 2020,2020,1 gene,32088390-Liu-2020,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23267,PHI:124944,UniProt,A7E6C4,GenBank,EDN91446,,,1980,PEIE1 (Ss1G_00849),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39477937,PubMed,10.1038/s41467-024-53725-0,Nat Commun. 2024 Oct 30;15(1):9391.,jiasencheng@mail.hzau.edu.cn,ΔSsPEIE1 mutants caused significantly smaller disease lesions than the wildtype strain on Arabidopsis leaves.,X Liu 2024,2024,1 gene,39477937-Liu-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23268,PHI:124944,UniProt,A7E6C4,GenBank,EDN91446,,,1980,PEIE1 (Ss1G_00849),,,,,,,5180,Sclerotinia sclerotiorum,665079,1980,white mould,eudicot,3708,Brassica napus (related: rape),,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39477937,PubMed,10.1038/s41467-024-53725-0,Nat Commun. 2024 Oct 30;15(1):9391.,jiasencheng@mail.hzau.edu.cn,ΔSsPEIE1 mutants caused significantly smaller disease lesions than the wildtype strain.,X Liu 2024,2024,1 gene,39477937-Liu-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23269,PHI:124945,UniProt,A0A194UQA0,GenBank,KUI53834,,,SXYL134,FSTF1 (KUI53834.1),chromosome unknown,,,,,,694573,Valsa pyri,,Vp297,Valsa canker,eudicots,23211,Pyrus communis (related: pear),,,,Leaves; Branches,fungal-specific transcription factor 1,,,,reduced virulence,,,,,smaller lesions,,,reduced,,no,hydrogen peroxide (H2O2);salicylic acid,hydrogen peroxide (H2O2): CHEBI:16240; ;salicylic acid: CHEBI:16914,,,,,gene deletion: full ; gene complementation,,,NN,31998257,PubMed,10.3389/fmicb.2019.02945,Front Microbiol. 2020 Jan 10;10:2945.,mengzhonghefeng_20@163.com,"Compared with the WT lesion diameters, the mutant lesion diameters were slightly reduced on pear leaves and branches at 3 dpi and significantly reduced at 5 dpi.",A M Kange 2020,2020,1 gene,31998257-Kange-2019,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23270,PHI:124946,UniProt,G4N1T8,GenBank,EHA52453,,,70-15,Gep4 (XP_003712260.1),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4530,Oryza sativa (related: rice),Lijiangxintuanheigu,,,Leaves,cardiolipin biosynthesis-related gene,,,Mps1-MAPK signaling pathway,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,wild type,no,sorbitol;hydrogen peroxide (H2O2);CaCl2;NaCl;ethidium bromide;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;ethidium bromide: CHEBI:4883; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39477586,PubMed,10.1016/j.pestbp.2024.106134,Pestic Biochem Physiol. 2024 Nov;205:106134.,li4@mail.hzau.edu.cn,"Mogep4 failed to develop lesions at 6 dpi, whereas the control strains caused abundant typical necrotic blast lesions.",M Zhu 2024,2024,3 genes,39477586-Zhu-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23271,PHI:124946,UniProt,G4N1T8,GenBank,EHA52453,,,70-15,Gep4 (XP_003712260.1),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4513,Hordeum vulgare (related: barley),E9,,,Leaves,cardiolipin biosynthesis-related gene,,,Mps1-MAPK signaling pathway,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,wild type,no,sorbitol;hydrogen peroxide (H2O2);CaCl2;NaCl;ethidium bromide;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;ethidium bromide: CHEBI:4883; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39477586,PubMed,10.1016/j.pestbp.2024.106134,Pestic Biochem Physiol. 2024 Nov;205:106134.,li4@mail.hzau.edu.cn,"Mogep4 failed to develop lesions at 6 dpi, whereas the control strains caused abundant typical necrotic blast lesions.",M Zhu 2024,2024,3 genes,39477586-Zhu-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23272,PHI:124947,UniProt,G4MV50,GenBank,EHA54065,,,70-15,Cld1 (XP_003713872.1),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4513,Hordeum vulgare (related: barley),E9,,,Leaves,phosphatidyl synthase,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,39477586,PubMed,10.1016/j.pestbp.2024.106134,Pestic Biochem Physiol. 2024 Nov;205:106134.,li4@mail.hzau.edu.cn,"Abundant typical necrotic lesions developed on leaves inoculated with WT, Mocld1, Motaz1, and Mogep4 complementation strains.",M Zhu 2024,2024,3 genes,39477586-Zhu-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23273,PHI:124948,UniProt,G4MTA6,GenBank,EHA53852,,,70-15,Taz1 (XP_003713659.1),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4513,Hordeum vulgare (related: barley),E9,,,Leaves,tafazzin family protein,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,39477586,PubMed,10.1016/j.pestbp.2024.106134,Pestic Biochem Physiol. 2024 Nov;205:106134.,li4@mail.hzau.edu.cn,"Abundant typical necrotic lesions developed on leaves inoculated with WT, Mocld1, Motaz1, and Mogep4 complementation strains.",M Zhu 2024,2024,3 genes,39477586-Zhu-2024,BATCH_139,2024-11-01,MC,,,,,,,,,,,,,
,,Record 23274,PHI:124949,UniProt,G2WVZ6,GenBank,EGY19766,,,VdLs.17,PE1 (VDAG_01782),chromosome 7,,,,,,27337,Verticillium dahliae,,Vd592,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),Xinluzao 7,,,Seedlings: Stems,pectinesterase,,,flavonoid biosynthesis pathway,reduced virulence,,,,,mild disease,,,,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,39590692,PubMed,10.3390/jof10110773,J Fungi (Basel). 2024 Nov 7;10(11):773.,liufeng0993@sina.com,"Compared with the pTRV2-00 plants, the pTRV2-VdPE1-treated seedlings showed milder disease symptoms, including lighter necrosis, wilting, and vascular discoloration.",Y Li 2024,2024,1 gene,39590692-Li-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23275,PHI:124950,UniProt,G4N1T8,GenBank,EHA52453,,,70-15,Gep4 (XP_003712260.1),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4530,Oryza sativa (related: rice),Lijiangxintuanheigu,,,Leaves,cardiolipin biosynthesis-related enzyme,,,Mps1-MAPK signaling pathway,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,wild type,no,Congo red;calcofluor white (CFW),Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33007450,PubMed,10.1016/j.fgb.2020.103474,Fungal Genet Biol. 2020 Dec;145:103474.,leeguotian@163.com,"Mogep4 failed to develop lesions at 6 dpi, whereas the control strains caused abundant typical necrotic blast lesions.",X Zhao 2020,2020,3 genes,33007450-Zhao-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23276,PHI:124950,UniProt,G4N1T8,GenBank,EHA52453,,,70-15,Gep4 (XP_003712260.1),chromosome 3,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4513,Hordeum vulgare (related: barley),E9,,,Leaves,cardiolipin biosynthesis-related enzyme,,,Mps1-MAPK signaling pathway,loss of pathogenicity,,,yes,,no lesion,reduced,,reduced,wild type,no,Congo red;calcofluor white (CFW),Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,33007450,PubMed,10.1016/j.fgb.2020.103474,Fungal Genet Biol. 2020 Dec;145:103474.,leeguotian@163.com,"Mogep4 failed to develop lesions at 6 dpi, whereas the control strains caused abundant typical necrotic blast lesions.",X Zhao 2020,2020,3 genes,33007450-Zhao-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23277,PHI:124951,UniProt,G4MV50,GenBank,EHA54065,,,70-15,Cld1 (XP_003713872.1),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4513,Hordeum vulgare (related: barley),E9,,,Leaves,phosphatidyl synthase,,,,unaffected pathogenicity,,,yes,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,33007450,PubMed,10.1016/j.fgb.2020.103474,Fungal Genet Biol. 2020 Dec;145:103474.,leeguotian@163.com,Mocld11 develop same lesions as wild type.,X Zhao 2020,2020,3 genes,33007450-Zhao-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23278,PHI:124952,UniProt,G4MTA6,GenBank,EHA53852,,,70-15,Taz1 (XP_003713659.1),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocot,4513,Hordeum vulgare (related: barley),E9,,,Leaves,tafazzin family protein,,,,unaffected pathogenicity,,,yes,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,33007450,PubMed,10.1016/j.fgb.2020.103474,Fungal Genet Biol. 2020 Dec;145:103474.,leeguotian@163.com,Motaz1 develop same lesions as wild type.,X Zhao 2020,2020,3 genes,33007450-Zhao-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23279,PHI:124953,UniProt,G4NKT8,GenBank,EHA45916,,,70-15,qpt1 (MGG_03028),chromosome 7,,,,,,318829,Magnaporthe oryzae,,,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,quinolinate phosphoribosyltransferase,,,NAD de novo biosynthetic pathway,unaffected pathogenicity,,,no,,wild type,,,increased,,no,,,,,,,gene deletion: full,,,NN,31517594,PubMed,10.1099/mic.0.000855,Microbiology (Reading). 2019 Nov;165(11):1198-1202.,rwilson10@unl.edu,Δqpt1 showed necrotic lesions on rice leaves that were indistinguishable from wildtype.,R A Wilson 2019,2019,1 gene,31517594-Wilson-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23280,PHI:124954,UniProt,I1RZP1,GenBank,CEF75192,,,PH-1,GET3 ( FGSG_09891),chromosome 1,,,,,,5518,Fusarium graminearum,,DAOM180378,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),SM482,,,Spikelets,ATPase protein,,,GET pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,sorbitol;hydrogen peroxide (H2O2);NaCl;CuSO4;sodium dodecyl sulphate (SDS);dithiothreitol (DTT);carbendazim;tebuconazole;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;CuSO4: CHEBI:23414; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;dithiothreitol (DTT): CHEBI:42170; ;carbendazim: CHEBI:3392; ;tebuconazole: CHEBI:81781; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39596240,PubMed,10.3390/ijms252212172,Int J Mol Sci. 2024 Nov 13;25(22):12172.,ymwei@sicau.edu.cn,"Deletion of FgGET3 in F. graminearum results in decreased fungal growth, fragmented vacuoles, altered abiotic stress responses, reduced conidia production, delayed conidial germination, weakened virulence on wheat spikes.",C Liu 2024,2024,1 gene,39596240-Liu-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23281,PHI:124955,UniProt,W7LVV1,GenBank,EWG36676,,,7600,Syn1 (FVEG_00594),chromosome 1,,,,,,117187,Fusarium verticillioides,334819; no data found,7600 and 7598,maize ear rot,monocot,4577,Zea mays (related: maize),Silver Queen,,,mesocotyls,SNARE protein,,,,reduced virulence,,,,,smaller lesions,reduced,wild type,reduced,wild type,no,sorbitol;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,31390325,PubMed,10.1099/mic.0.000843,Microbiology (Reading). 2019 Oct;165(10):1075-1085.,huanzhfly@gmail.com,"Seedlings inoculated with ΔFvsyn1, ΔSNARE and ΔSynN mutants showed significantly reduced levels of rot; approximately 60, 50 and 40 % reductions compared to wild type.",H Zhang 2019,2019,1 gene,31390325-Zhang-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23282,PHI:124956,UniProt,A0A0I9ZBA9,GenBank,VTT55369,,,C2S,MEP1,,,,,,,42676,Fusarium sacchari,,CNO-1,pokkah boeng disease,monocot,4547,Saccharum officinarum (related: sugarcane),Zhongzhe No. 1,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,small necrotic lesions,wild type,,wild type,,no,sucrose,sucrose: CHEBI:17992,,,,,gene deletion: full ; gene complementation,,,NN,39596144,PubMed,10.3390/ijms252212075,Int J Mol Sci. 2024 Nov 10;25(22):12075.,huqin-0509@gxu.edu.cn,"The necrotic lesions on the leaves inoculated with ΔFsMEP1 were smaller than those induced by the WT, and Com-ΔFsMEP1 restored the virulence of ΔFsMEP1 at 120 h post-inoculation.",L Wang 2024,2024,1 gene,39596144-Wang-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23283,PHI:124957,UniProt,G4MWF1,GenBank,EHA55911,,,70-15,cdc4 (MGG_08345),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"ΔMocdc4, ΔMogrr1 and ΔMofwd1 caused fewer lesions in comparison with Guy11, which produced a large number of typical lesions.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23284,PHI:124958,UniProt,G4NEL3,GenBank,EHA48643,,,70-15,Fbx15 (MGG_00768),chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23285,PHI:124959,UniProt,G4NAK2,GenBank,EHA51340,,,70-15,Fwd1 (MGG_09696),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,cAMP-PKA signalling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"ΔMocdc4, ΔMogrr1 and ΔMofwd1 caused fewer lesions in comparison with Guy11, which produced a large number of typical lesions.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23286,PHI:124960,UniProt,L7JEN6,GenBank,ELQ66701,,,P131,Grr1,chromosome unknown,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,reduced virulence,,,yes,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"ΔMocdc4, ΔMogrr1 and ΔMofwd1 caused fewer lesions in comparison with Guy11, which produced a large number of typical lesions.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23287,PHI:124961,UniProt,G4NDC1,GenBank,EHA49259,,,70-15,MGG_00261,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23288,PHI:124962,UniProt,G4NCI0,GenBank,EHA48277,,,70-15,MGG_01077,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23289,PHI:124963,UniProt,G4N5I4,GenBank,EHA52177,,,70-15,MGG_06117,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23290,PHI:124964,UniProt,G4N0G2,GenBank,EHA52296,,,70-15,MGG_06215,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23291,PHI:124965,UniProt,G4N7S9,GenBank,EHA50883,,,70-15,MGG_06372,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23292,PHI:124966,UniProt,G4N0R7,GenBank,EHA51500,,,70-15,MGG_07421,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23293,PHI:124967,UniProt,G4N160,GenBank,EHA51539,,,70-15,MGG_07448,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23294,PHI:124968,UniProt,G4MX66,GenBank,EHA55165,,,70-15,MGG_08019,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23295,PHI:124969,UniProt,G4MPV5,GenBank,EHA57252,,,70-15,MGG_09240,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23296,PHI:124970,UniProt,G4NA25,GenBank,EHA51271,,,70-15,MGG_09760,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23297,PHI:124971,UniProt,G4NGA8,GenBank,EHA47065,,,70-15,MGG_10415,chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23298,PHI:124972,UniProt,G4ND05,GenBank,EHA49195,,,70-15,MGG_11604,chromosome 5,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23299,PHI:124973,UniProt,G4MN49,GenBank,EHA57863,,,70-15,MGG_13129,chromosome 1,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23300,PHI:124974,UniProt,G4N723,GenBank,EHA49936,,,70-15,MGG_13493,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23301,PHI:124975,UniProt,G4NAK5,GenBank,EHA51343,,,70-15,MGG_13660,chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23302,PHI:124976,UniProt,G4MWD0,GenBank,EHA55890,,,70-15,MGG_15933,chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23303,PHI:124977,UniProt,G4N3R5,GenBank,EHA51889,,,70-15,MGG_16709,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,F-box protein,,,,unaffected pathogenicity,,,yes,,wild type,,,,,no,,,,,,,gene deletion: full,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"F-box deletion mutants, including ΔMofbx15, displayed a similar level of infection as Guy11.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23304,PHI:124957,UniProt,G4MWF1,GenBank,EHA55911,,,70-15,cdc4 (MGG_08345),chromosome 2,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),Golden Promise,,,Leaves,F-box protein,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,ΔMocdc4 and ΔMofwd1 mutants caused smaller disease lesions compared with Guy11 and the complemented strains.,H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23305,PHI:124959,UniProt,G4NAK2,GenBank,EHA51340,,,70-15,Fwd1 (MGG_09696),chromosome 4,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),Golden Promise,,,Leaves,F-box protein,,,cAMP-PKA signalling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,ΔMocdc4 and ΔMofwd1 mutants caused smaller disease lesions compared with Guy11 and the complemented strains.,H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23306,PHI:124957,UniProt,G4MWF1,GenBank,EHA55911,,,70-15,cdc4 (MGG_08345),chromosome 2,ΔF-box,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),Golden Promise,,,Leaves,F-box protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,ΔMocdc4ΔF-box displayed a similar level of infection compared to Guy11.,H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23307,PHI:124959,UniProt,G4NAK2,GenBank,EHA51340,,,70-15,Fwd1 (MGG_09696),chromosome 4,ΔF-box,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),Golden Promise,,,Leaves,F-box protein,,,cAMP-PKA signalling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,ΔMofwd1ΔF-box displayed a similar level of infection compared to Guy11.,H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23308,PHI:124958,UniProt,G4NEL3,GenBank,EHA48643,,,70-15,Fbx15 (MGG_00768),chromosome 5,ΔF-box,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4513,Hordeum vulgare (related: barley),Golden Promise,,,Leaves,F-box protein,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,ΔMofbx15ΔF-box displayed a similar level of infection compared to Guy11.,H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23309,PHI:124978,UniProt,G4NH56,GenBank,EHA47566,,,70-15,Frq,chromosome 6,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,FRQ-interacting RNA helicase,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31145534,PubMed,10.1111/1462-2920.14699,Environ Microbiol. 2019 Aug;21(8):3027-3045. doi: 10.1111/1462-2920.14699. Epub 2019 Jun 18,xhliu@zju.edu.cn,"Disruption of MoFRQ caused slow growth, reduced conidiation, conidial germination and virulence.",H B Shi 2019,2019,22 genes,31145534-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23310,PHI:124979,UniProt,G2WQ55,GenBank,EGY13815,,,VdLs.17,Acb1 (VDAG_03042),chromosome 2,,,,,,27337,Verticillium dahliae,,Vd991,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Junmian 1,,,Leaves,acyl-CoA-binding protein,,,,reduced virulence,,,no,,less symptoms,wild type,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39650135,PubMed,10.1007/s42994-024-00175-3,aBIOTECH. 2024 Jul 13;5(4):431-448. doi: 10.1007/s42994-024-00175-3. eCollection 2024 Dec,tianlister@163.com,"The typical symptoms of Verticillium wilt caused by the wildtype strain Vd991, such as the yellowing of plant leaves, were reduced in plants inoculated with the VdAcb1 deletion strain and correspondingly, the browning of cotton vascular tissue was also reduced",J Zhuang 2024,2024,1 gene,39650135-Zhuang-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23311,PHI:124980,UniProt,A0A0F7S5V2,GenBank,CDU22680,,,SscI8,Prf1,,,,,,,49012,Sporisorium scitamineum,1447027; no data found,JG36 and JG35,sugarcane smut,monocot,4547,Saccharum officinarum (related: sugarcane),ROC22,,,Seedlings,pheromone response factor,,,cAMP-PKA signaling pathway,loss of pathogenicity,,,,,no visible disease,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31552011,PubMed,10.3389/fmicb.2019.02115,Front Microbiol. 2019 Sep 10;10:2115.,chenbs2008@163.com,"SsPRF1 null mutant remained healthy throughout the observed period of 120 days, plants infected with wild-type combination JG36/JG35 displayed severe stunting, spindly stalks and upright and narrower leaves after 60 days, and whips emerged from the shoots at 90–120 days post-inoculation.",G Zhu 2019,2019,1 gene,31552011-Zhu-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23312,PHI:124981,UniProt,A0A0U5FJA3,GenBank,CEG18777,,,,ecnA,,,,,,,611301,Xanthomonas citri,1203463,subsp. Citri 306,Citrus canker,eudicot,2711,Citrus sinensis (related: sweet orange),Bahia,,,Leaves,antitoxin,,,,reduced virulence,,,,,less symptoms,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,31358614,PubMed,10.1128/JB.00796-18,J Bacteriol. 2019 Sep 20;201(20):e00796-18.,desouza@ccsm.br,The symptoms was clearly reduced in ΔecnA mutant compared to those of the leaves infiltrated with the wild-type strain.,L M Granato 2019,2019,1 gene,31358614-Granato-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23313,PHI:124982,UniProt,G4N014,GenBank,EHA52252,,,70-15,ACB1,chromosome 3,,,,,,318829,Magnaporthe oryzae,,Guy11,rice blast,monocot,4530,Oryza sativa (related: rice),CO-39,,,Leaves,acyl-CoA-binding protein,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39585916,PubMed,10.1371/journal.ppat.1012738,PLoS Pathog. 2024 Nov 25;20(11):e1012738.,rwilson10@unl.edu,The Δacb1 mutant strain exhibited poor vegetative growth and and reduce virulence.,M Richter 2024,2024,1 gene,39585916-Richter-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23314,PHI:124983,UniProt,A7ES62,GenBank,EDN92304,,,1980,Ptc3 (SS1G_08167),,,,SsAtg1,UniProt: A7F0W2; GenBank: EDN95354,,5180,Sclerotinia sclerotiorum,,UF-1,white mould,eudicot,4081,Solanum lycopersicum (related: tomato),,,,Leaves,2C ser/Thr phosphatase,,,MAP kinase signalling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,sorbitol;NaCl;KCl;glucose;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;glucose: CHEBI:17234; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39617958,PubMed,10.1111/mpp.70037,Mol Plant Pathol. 2024 Dec;25(12):e70037.,panhongyu@jlu.edu.cn,"Loss of function ΔSsptc3 mutants displayed defects in mycelial growth, sclerotia formation and reduced virulence.",W Jiao 2024,2024,1 gene,39617958-Jiao-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23315,PHI:124983,UniProt,A7ES62,GenBank,EDN92304,,,1980,Ptc3 (SS1G_08167),,,,SsAtg1,UniProt: A7F0W2; GenBank: EDN95354,,5180,Sclerotinia sclerotiorum,,UF-1,white mould,eudicot,3847,Glycine max (related: soybean),,,,Leaves,2C ser/Thr phosphatase,,,MAP kinase signalling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,sorbitol;NaCl;KCl;glucose;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;glucose: CHEBI:17234; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39617958,PubMed,10.1111/mpp.70037,Mol Plant Pathol. 2024 Dec;25(12):e70037.,panhongyu@jlu.edu.cn,"Loss of function ΔSsptc3 mutants displayed defects in mycelial growth, sclerotia formation and reduced virulence.",W Jiao 2024,2024,1 gene,39617958-Jiao-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23316,PHI:124983,UniProt,A7ES62,GenBank,EDN92304,,,1980,Ptc3 (SS1G_08167),,,,SsAtg1,UniProt: A7F0W2; GenBank: EDN95354,,5180,Sclerotinia sclerotiorum,,UF-1,white mould,eudicot,4072,Capsicum annuum (no common name found),,,,Leaves,2C ser/Thr phosphatase,,,MAP kinase signalling pathway,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,sorbitol;NaCl;KCl;glucose;Congo red;calcofluor white (CFW),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;glucose: CHEBI:17234; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39617958,PubMed,10.1111/mpp.70037,Mol Plant Pathol. 2024 Dec;25(12):e70037.,panhongyu@jlu.edu.cn,"Loss of function ΔSsptc3 mutants displayed defects in mycelial growth, sclerotia formation and reduced virulence.",W Jiao 2024,2024,1 gene,39617958-Jiao-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23317,PHI:124984,UniProt,A0A0F7S9M8,GenBank,CDR87150,,,SscI8,Agc1,,,,,,,49012,Sporisorium scitamineum,,MAT-1,sugarcane smut,monocot,4547,Saccharum officinarum (related: sugarcane),ROC22,,,Seedlings,AGC kinase,,,AGC signaling pathway,loss of pathogenicity,,,,,no symptom,,,reduced,,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full ; gene complementation,,,NN,31142621,PubMed,10.1128/mSphere.00259-19,mSphere. 2019 May 29;4(3):e00259-19.,,Seedlings infected by WT x ssagc1Δ combination remained healthy through the observed period of 180 days and never developed whip symptom compared to wild type.,Y Wang 2019,2019,1 gene,31142621-Wang-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23318,PHI:124985,UniProt,A0AAE7CYC7,GenBank,QIZ49824,,,CE1,speA,,,,,,,204042,Dickeya zeae,1427366,EC1,soft rot diseases,monocot,4530,Oryza sativa (related: rice),CO-39,,,Seed,arginine decarboxylase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31497009,PubMed,10.3389/fmicb.2019.01950,Front Microbiol. 2019 Aug 21;10:1950.,lhzhang01@scau.edu.cn,Deletion of speA reduced the bacterial virulence by about 35% at 10 bacterial cells.,Z Shi 2019,2019,3 genes,31497009-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23319,PHI:124985,UniProt,A0AAE7CYC7,GenBank,QIZ49824,,,CE1,speA,,,,,,PHI:124986; PHI:124987,204042,Dickeya zeae,1427366,EC1,soft rot diseases,monocot,4530,Oryza sativa (related: rice),CO-39,,,Seed,arginine decarboxylase,,,,unaffected pathogenicity,,,,,,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31497009,PubMed,10.3389/fmicb.2019.01950,Front Microbiol. 2019 Aug 21;10:1950.,lhzhang01@scau.edu.cn,Triple deletion of ΔspeAΔpotFΔplaP showed the bacterial virulence same as wild type.,Z Shi 2019,2019,3 genes,31497009-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23320,PHI:124986,UniProt,A0AAE7CZY9,GenBank,QIZ51444,,,CE1,potF,,,,,,PHI:124985; PHI:124987,204042,Dickeya zeae,1427366,EC1,soft rot diseases,monocot,4530,Oryza sativa (related: rice),CO-39,,,Seed,transporter gene,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,31497009,PubMed,10.3389/fmicb.2019.01950,Front Microbiol. 2019 Aug 21;10:1950.,lhzhang01@scau.edu.cn,Triple deletion of ΔspeAΔpotFΔplaP showed the bacterial virulence same as wild type.,Z Shi 2019,2019,3 genes,31497009-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23321,PHI:124987,UniProt,A0A2K9QEF8,GenBank,QIZ51363,,,CE1,plaP,,,,,,PHI:124985; PHI:124986,204042,Dickeya zeae,1427366,EC1,soft rot diseases,monocot,4530,Oryza sativa (related: rice),CO-39,,,Seed,transporter gene,,,,unaffected pathogenicity,,,,,,,,reduced,,no,,,,,,,gene deletion: full,,,NN,31497009,PubMed,10.3389/fmicb.2019.01950,Front Microbiol. 2019 Aug 21;10:1950.,lhzhang01@scau.edu.cn,Triple deletion of ΔspeAΔpotFΔplaP showed the bacterial virulence same as wild type.,Z Shi 2019,2019,3 genes,31497009-Shi-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23322,PHI:124988,UniProt,A0A6B7L9I7,GenBank,QEX50886,,,,Avr4 (MH673051),,,,,,,1868926,Cercospora cf. flagellaris,,MRL 6020 2B,cercospora leaf blight,eudicots,3847,Glycine max (related: soybean),Syngenta 02JR423003,,,Leaves,effector protein,,,cercosporin pathway,effector (plant avirulence determinant),,,,,small necrotic lesions,,,reduced,,no,,,,,,,gene deletion: full,,,NN,31642594,PubMed,10.1111/mpp.12879,Mol Plant Pathol. 2020 Jan;21(1):53-65.,zchen@agcenter.lsu.edu,The mutants incited smaller necrotic and chlorotic lesions compared to the wild-type.,J Santos Rezende 2020,2020,1 gene,31642594-Santos Rezende-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23323,PHI:124989,UniProt,W7LWY3,GenBank,EWG39980,,,7600,Gbb2 (FVEG_02582),chromosome 5,,,,,,117187,Fusarium verticillioides,,,maize ear rot,monocot,94108,Zantedeschia elliotiana (no common name found),B73,,,root,G beta-like protein,,,MAP kinase pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;sucrose;sodium dodecyl sulphate (SDS),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sucrose: CHEBI:17992; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full ; gene complementation,,,NN,31760684,PubMed,10.1111/1462-2920.14875,Environ Microbiol. 2020 Feb;22(2):615-628. doi: 10.1111/1462-2920.14875. Epub 2019 Dec 3,,Single mutant ΔFvgbb2 exhibits reduce virulence compared to wild type.,H Yan 2020,2020,3 genes,31760684-Yan-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23324,PHI:124990,UniProt,W7N386,GenBank,EWG51237,,,7600,Gbb1 (FVEG_10291),chromosome 9,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocot,94108,Zantedeschia elliotiana (no common name found),B73,,,root,G beta-like protein,,,MAP kinase pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;sucrose;sodium dodecyl sulphate (SDS),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sucrose: CHEBI:17992; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full ; gene complementation,,,NN,31760684,PubMed,10.1111/1462-2920.14875,Environ Microbiol. 2020 Feb;22(2):615-628. doi: 10.1111/1462-2920.14875. Epub 2019 Dec 3,,Single mutant ΔFvgbb1 exhibits reduce virulence compared to wild type.,H Yan 2020,2020,3 genes,31760684-Yan-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23325,PHI:124991,UniProt,W7MBR4,GenBank,EWG42327,,,7600,Gpa2 (FVEG_04170),chromosome 2,,,,,,117187,Fusarium verticillioides,,M3125,maize ear rot,monocot,94108,Zantedeschia elliotiana (no common name found),B73,,,root,G beta-like protein,,,MAP kinase pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;sucrose;sodium dodecyl sulphate (SDS),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sucrose: CHEBI:17992; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full ; gene complementation,,,NN,31760684,PubMed,10.1111/1462-2920.14875,Environ Microbiol. 2020 Feb;22(2):615-628. doi: 10.1111/1462-2920.14875. Epub 2019 Dec 3,,Single mutant ΔFvgpa2 exhibits reduce virulence compared to wild type.,H Yan 2020,2020,3 genes,31760684-Yan-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23326,PHI:124989,UniProt,W7LWY3,GenBank,EWG39980,,,7600,Gbb2 (FVEG_02582),chromosome 5,,,,,PHI:124990,117187,Fusarium verticillioides,,,maize ear rot,monocot,94108,Zantedeschia elliotiana (no common name found),B73,,,root,G beta-like protein,,,MAP kinase pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;sucrose;sodium dodecyl sulphate (SDS),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sucrose: CHEBI:17992; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full,,,NN,31760684,PubMed,10.1111/1462-2920.14875,Environ Microbiol. 2020 Feb;22(2):615-628. doi: 10.1111/1462-2920.14875. Epub 2019 Dec 3,,Double mutants ΔFvgbb2-gbb1 exhibits reduce virulence compared to wild type.,H Yan 2020,2020,3 genes,31760684-Yan-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23327,PHI:124990,UniProt,W7N386,GenBank,EWG51237,,,7600,Gbb1 (FVEG_10291),chromosome 9,,,,,PHI:124989,117187,Fusarium verticillioides,,M3125,maize ear rot,monocot,94108,Zantedeschia elliotiana (no common name found),B73,,,root,G beta-like protein,,,MAP kinase pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;sucrose;sodium dodecyl sulphate (SDS),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sucrose: CHEBI:17992; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full,,,NN,31760684,PubMed,10.1111/1462-2920.14875,Environ Microbiol. 2020 Feb;22(2):615-628. doi: 10.1111/1462-2920.14875. Epub 2019 Dec 3,,Double mutants ΔFvgbb2-gbb1 exhibits reduce virulence compared to wild type.,H Yan 2020,2020,3 genes,31760684-Yan-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23328,PHI:124989,UniProt,W7LWY3,GenBank,EWG39980,,,7600,Gbb2 (FVEG_02582),chromosome 5,,,,,PHI:124991,117187,Fusarium verticillioides,,,maize ear rot,monocot,94108,Zantedeschia elliotiana (no common name found),B73,,,root,G beta-like protein,,,MAP kinase pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;sucrose;sodium dodecyl sulphate (SDS),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sucrose: CHEBI:17992; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full,,,NN,31760684,PubMed,10.1111/1462-2920.14875,Environ Microbiol. 2020 Feb;22(2):615-628. doi: 10.1111/1462-2920.14875. Epub 2019 Dec 3,,Double mutants ΔFvgbb2-gpa2 exhibits reduce virulence compared to wild type.,H Yan 2020,2020,3 genes,31760684-Yan-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23329,PHI:124991,UniProt,W7MBR4,GenBank,EWG42327,,,7600,Gpa2 (FVEG_04170),chromosome 2,,,,,PHI:124989,117187,Fusarium verticillioides,,M3125,maize ear rot,monocot,94108,Zantedeschia elliotiana (no common name found),B73,,,root,G beta-like protein,,,MAP kinase pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;sucrose;sodium dodecyl sulphate (SDS),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sucrose: CHEBI:17992; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full,,,NN,31760684,PubMed,10.1111/1462-2920.14875,Environ Microbiol. 2020 Feb;22(2):615-628. doi: 10.1111/1462-2920.14875. Epub 2019 Dec 3,,Double mutants ΔFvgbb2-gpa2 exhibits reduce virulence compared to wild type.,H Yan 2020,2020,3 genes,31760684-Yan-2020,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23330,PHI:124992,UniProt,Q7S2F7,GenBank,EAA29571,,,OR74A,ram1,,,,,,,49012,Sporisorium scitamineum,,MAT-1 × MAT-2,sugarcane smut,monocot,4547,Saccharum officinarum (related: sugarcane),ROC22,,,Seedlings,farnesyltransferase beta subunit,,,,reduced virulence,,,,,less symptoms,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,31134021,PubMed,10.3389/fmicb.2019.00976,Front Microbiol. 2019 May 8;10:976.,changcq@scau.edu.cn,"The ram1Δ × MAT-2 combination displayed significantly reduced pathogenicity, with only around 10% of the infected seedlings showing black whip symptoms at 200 dpi compared to wild type.",S Sun 2019,2019,1 gene,31134021-Sun-2019,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23331,PHI:124993,UniProt,I1RXF5,GenBank,CEF85498,,,PH-1,lncRsn (FGSG_09021),chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),,,,Spikelets; Coleoptiles; Corn silk,antisense long non-coding RNA,,,,reduced virulence,,,yes,,smaller lesions,reduced,reduced,reduced,wild type,no,hydrogen peroxide (H2O2);CaCl2;NaCl;MgCl2;KCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;MgCl2: CHEBI:6636; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full,,,NN,39452644,PubMed,10.3390/jof10100692,J Fungi (Basel). 2024 Oct 3;10(10):692.,liyanli@yangtzeu.edu.cn,"The wild-type strain PH-1 caused disease lesions that were 16.36 ± 0.31 mm in length, whereas the lncRsn mutant strain only caused 10.68 ± 0.64 mm of lesions.",Z Fu 2024,2024,1 gene,39452644-Fu-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23332,PHI:124994,UniProt,D3J127,GenBank,ADC35363,,,,Slt2 (XP_018391030.1),,,,,,,5599,Alternaria alternata,,JT-03,brown spot disease,eudicot,23211,Pyrus communis (related: pear),,,,fruit,mitogen-activated protein kinase,,,,reduced virulence,,,,,smaller lesions,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39590693,PubMed,10.3390/jof10110774,J Fungi (Basel). 2024 Nov 7;10(11):774.,lyc@gsau.edu.cn,"ΔAaSlt2 strain was sensitive to cell wall inhibitors, and showed significantly reduced virulence on pear fruit.",Q Jiang 2024,2024,1 gene,39590693-Jiang-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23333,PHI:124995,UniProt,F9XBP2,GenBank,EGP87656,,,IPO323,Zt-11,chromosome 5,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocot,4565,Triticum aestivum (related: bread wheat),Longbow,,,Leaves,effector protein,,,,effector (plant avirulence determinant),,,,,low disease severity,reduced,,wild type,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,39561154,PubMed,10.1371/journal.pone.0313859,PLoS One. 2024 Nov 19;19(11):e0313859.,angela.feechan@ucd.ie,"The leaves infected with ΔZt-11 strains developed chlorotic lesions only from 13 dpi, followed by necrosis and pycnidia production from 17 dpi compared to wild type.",S J Karki 2024,2024,1 gene,39561154-Karki-2024,BATCH_140A,2024-12-01,MC,,,,,,,,,,,,,
,,Record 23334,PHI:125047,UniProt,G2X5P4,GenBank,EGY14385,,,VdLs.17,CreC,chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Junmian No. 1,,,Seedlings,carbon catabolite repression gene,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39519126,PubMed,10.3390/ijms252111575,Int J Mol Sci. 2024 Oct 28;25(21):11575.,lqg@nwafu.edu.cn,"ΔVdCreA and ΔVdCreC exhibited markedly reduced virulence in cotton plants compared with the V592 strain, which induced severe tissue chlorosis and wilt symptoms .",Y Wang 2024,2024,2 genes,39519126-Wang-2024,BATCH_140B,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23335,PHI:125048,UniProt,G2WQE4,GenBank,EGY13904,,,VdLs.17,CreA,chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Junmian No. 1,,,Seedlings,carbon catabolite repression gene,,,,reduced virulence,,,,,low disease severity,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39519126,PubMed,10.3390/ijms252111575,Int J Mol Sci. 2024 Oct 28;25(21):11575.,lqg@nwafu.edu.cn,"ΔVdCreA and ΔVdCreC exhibited markedly reduced virulence in cotton plants compared with the V592 strain, which induced severe tissue chlorosis and wilt symptoms .",Y Wang 2024,2024,2 genes,39519126-Wang-2024,BATCH_140B,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23336,PHI:125047,UniProt,G2X5P4,GenBank,EGY14385,,,VdLs.17,CreC,chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Junmian No. 1,,,Seedlings,carbon catabolite repression gene,,,,unaffected pathogenicity,,,,,low disease severity,increased,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39519126,PubMed,10.3390/ijms252111575,Int J Mol Sci. 2024 Oct 28;25(21):11575.,lqg@nwafu.edu.cn,Overexpression of VdCreA and VdCreC exhibited same virulence in cotton plants compared with the V592 strain.,Y Wang 2024,2024,2 genes,39519126-Wang-2024,BATCH_140B,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23337,PHI:125048,UniProt,G2WQE4,GenBank,EGY13904,,,VdLs.17,CreA,chromosome 2,,,,,,27337,Verticillium dahliae,,V592,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Junmian No. 1,,,Seedlings,carbon catabolite repression gene,,,,unaffected pathogenicity,,,,,wild type,reduced,,wild type,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39519126,PubMed,10.3390/ijms252111575,Int J Mol Sci. 2024 Oct 28;25(21):11575.,lqg@nwafu.edu.cn,Overexpression of VdCreA and VdCreC exhibited same virulence in cotton plants compared with the V592 strain.,Y Wang 2024,2024,2 genes,39519126-Wang-2024,BATCH_140B,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23338,PHI:125049,UniProt,A0A3N0UC48,GenBank,ROH77781,,,L6_4B,cpxA,,,,,,,1172565,Lonsdalea populi,,N-5-1,poplar canker,eudicots,1217306,Populus x beijingensis (no common name found),,,,Twigs,two-component system,,,,loss of pathogenicity,,,,,no symptom,,,wild type,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,39548717,PubMed,10.1111/mpp.70029,Mol Plant Pathol. 2024 Nov;25(11):e70029.,li_aining@bjfu.edu.cn,"Virulence of ΔcpxR and ΔcpxA mutants was found to be completely lost in contrast to that of the wild-type strain, whereas the degree of pathogenicity of the complementary strain was similar to that of the wild-type strain.",R Yang 2024,2024,5 genes,39548717-Yang-2024,BATCH_140B,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23339,PHI:125050,UniProt,A0A3N0UB28,GenBank,ROH77780,,,L6_4B,cpxR,,,,FlhC; FlhB,UniProt: A0A3N0UD35; GenBank: ROH78131; UniProt: A0A3N0UCW8; GenBank: ROH78122,,1172565,Lonsdalea populi,,N-5-1,poplar canker,eudicots,1217306,Populus x beijingensis (no common name found),,,,Twigs,two-component system,,,,loss of pathogenicity,,,,,no symptom,,,wild type,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,39548717,PubMed,10.1111/mpp.70029,Mol Plant Pathol. 2024 Nov;25(11):e70029.,li_aining@bjfu.edu.cn,"Virulence of ΔcpxR and ΔcpxA mutants was found to be completely lost in contrast to that of the wild-type strain, whereas the degree of pathogenicity of the complementary strain was similar to that of the wild-type strain.",R Yang 2024,2024,5 genes,39548717-Yang-2024,BATCH_140B,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23340,PHI:125051,UniProt,A0A3N0UD35,GenBank,ROH78131,,,L6_4B,FlhC,,,,,,,1172565,Lonsdalea populi,,N-5-1,poplar canker,eudicots,1217306,Populus x beijingensis (no common name found),,,,Twigs,flagellar transcriptional regulator,,,,loss of pathogenicity,,,,,no symptom,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39548717,PubMed,10.1111/mpp.70029,Mol Plant Pathol. 2024 Nov;25(11):e70029.,li_aining@bjfu.edu.cn,ΔflhC and ΔflhB mutants did not infect poplar trees.,R Yang 2024,2024,5 genes,39548717-Yang-2024,BATCH_140B,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23341,PHI:125052,UniProt,A0A3N0UCW8,GenBank,ROH78122,,,L6_4B,FlhB,,,,,,,1172565,Lonsdalea populi,,N-5-1,poplar canker,eudicots,1217306,Populus x beijingensis (no common name found),,,,Twigs,flagellar transcriptional regulator,,,,loss of pathogenicity,,,,,no symptom,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39548717,PubMed,10.1111/mpp.70029,Mol Plant Pathol. 2024 Nov;25(11):e70029.,li_aining@bjfu.edu.cn,ΔflhC and ΔflhB mutants did not infect poplar trees.,R Yang 2024,2024,5 genes,39548717-Yang-2024,BATCH_140B,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23342,PHI:125053,UniProt,A0A3N0URW7,GenBank,ROH83289,,,L6_4B,yccA,,,,,,,1172565,Lonsdalea populi,,N-5-1,poplar canker,eudicots,1217306,Populus x beijingensis (no common name found),,,,Twigs,membrane protein-coding gene,,,,loss of pathogenicity,,,,,no symptom,,,,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,39548717,PubMed,10.1111/mpp.70029,Mol Plant Pathol. 2024 Nov;25(11):e70029.,li_aining@bjfu.edu.cn,Deletion of yccA rendered L. populi nonpathogenic with significantly reduced biofilm formation ability.,R Yang 2024,2024,5 genes,39548717-Yang-2024,BATCH_140B,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23343,PHI:125054,UniProt,A0A4U7KVZ3,GenBank,TKY88884,,,CBS 10092,MFSST1,chromosome SGRAM_13,,,,,,49012,Sporisorium scitamineum,,Ss16,sugarcane smut,monocots,4547,Saccharum officinarum (related: sugarcane),ROC22,,,Seedlings,major facility superfamily sugar transporter protein,,,,reduced virulence,,,,,low disease severity,,,wild type,,no,NaCl;sodium dodecyl sulphate (SDS);Congo red,NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39745386,PubMed,10.1128/spectrum.01956-24,Microbiol Spectr. 2024 Dec 31:e0195624.,wkshen@scau.edu.cn,"Knockout mutant led to a significant reduction in disease incidence, with rates of 38%, 45%, and 42%.",Y Zhang 2024,2024,1 gene,39745386-Zhang-2024,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23344,PHI:125055,UniProt,F0Q6A2,GenBank,ADX44530,,,ATCC 19860,PilT (Acav_0607),,,,,,,862720,Acidovorax oryzae,,RS-2,bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedlings,type IV secretion system gene,,,,reduced virulence,,,,,increased seedling height,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,30468852,PubMed,10.1016/j.micpath.2018.11.017,Microb Pathog. 2019 Jan;126:343-350.,wqiu2015@zju.edu.cn,"When compared to the wild type strain, treatments with the 4 mutants ΔpilT, ΔpilM, ΔpilQ, and ΔpilZ3 caused a significant (P < 0.01) reduction in bacterial virulence.",S O Ogunyemi 2019,2019,9 genes,30468852-Ogunyemi-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23345,PHI:125056,UniProt,F0QAF6,GenBank,ADX44889,,,ATCC 19860,PilM (Acav_0967),,,,,,,862720,Acidovorax oryzae,,RS-2,bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedlings,type IV secretion system gene,,,,reduced virulence,,,,,increased seedling height,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,30468852,PubMed,10.1016/j.micpath.2018.11.017,Microb Pathog. 2019 Jan;126:343-350.,wqiu2015@zju.edu.cn,"When compared to the wild type strain, treatments with the 4 mutants ΔpilT, ΔpilM, ΔpilQ, and ΔpilZ3 caused a significant (P < 0.01) reduction in bacterial virulence.",S O Ogunyemi 2019,2019,9 genes,30468852-Ogunyemi-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23346,PHI:125057,UniProt,F0QAG0,GenBank,ADX44893,,,ATCC 19860,PilQ (Acav_0971),,,,,,,862720,Acidovorax oryzae,,RS-2,bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedlings,type IV secretion system gene,,,,reduced virulence,,,,,increased seedling height,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,30468852,PubMed,10.1016/j.micpath.2018.11.017,Microb Pathog. 2019 Jan;126:343-350.,wqiu2015@zju.edu.cn,"When compared to the wild type strain, treatments with the 4 mutants ΔpilT, ΔpilM, ΔpilQ, and ΔpilZ3 caused a significant (P < 0.01) reduction in bacterial virulence.",S O Ogunyemi 2019,2019,9 genes,30468852-Ogunyemi-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23347,PHI:125058,UniProt,F0QA19,GenBank,ADX47279,,,ATCC 19860,PilZ3 (Acav_3378),,,,,,,862720,Acidovorax oryzae,,RS-2,bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedlings,type IV secretion system gene,,,,reduced virulence,,,,,increased seedling height,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,30468852,PubMed,10.1016/j.micpath.2018.11.017,Microb Pathog. 2019 Jan;126:343-350.,wqiu2015@zju.edu.cn,"When compared to the wild type strain, treatments with the 4 mutants ΔpilT, ΔpilM, ΔpilQ, and ΔpilZ3 caused a significant (P < 0.01) reduction in bacterial virulence.",S O Ogunyemi 2019,2019,9 genes,30468852-Ogunyemi-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23348,PHI:125059,UniProt,F0Q6A0,GenBank,ADX44528,,,ATCC 19860,PilU (Acav_0605),,,,,,,862720,Acidovorax oryzae,,RS-2,bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedlings,type IV secretion system gene,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,30468852,PubMed,10.1016/j.micpath.2018.11.017,Microb Pathog. 2019 Jan;126:343-350.,wqiu2015@zju.edu.cn,"No significant (P > 0.05) difference in the pathogenicity is observed between the wild-type and the mutants ΔpilB, ΔpilU, ΔpilW, ΔpilZ1 and ΔpilZ2, which had a plant height of 2.60–3.03 cm.",S O Ogunyemi 2019,2019,9 genes,30468852-Ogunyemi-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23349,PHI:125060,UniProt,F0Q2Y1,GenBank,ADX45383,,,ATCC 19860,PilW (Acav_1461),,,,,,,862720,Acidovorax oryzae,,RS-2,bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedlings,type IV secretion system gene,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,30468852,PubMed,10.1016/j.micpath.2018.11.017,Microb Pathog. 2019 Jan;126:343-350.,wqiu2015@zju.edu.cn,"No significant (P > 0.05) difference in the pathogenicity is observed between the wild-type and the mutants ΔpilB, ΔpilU, ΔpilW, ΔpilZ1 and ΔpilZ2, which had a plant height of 2.60–3.03 cm.",S O Ogunyemi 2019,2019,9 genes,30468852-Ogunyemi-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23350,PHI:125061,UniProt,F0QCL1,GenBank,ADX47494,,,ATCC 19860,PilB (Acav_3595),,,,,,,862720,Acidovorax oryzae,,RS-2,bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedlings,type IV secretion system gene,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,30468852,PubMed,10.1016/j.micpath.2018.11.017,Microb Pathog. 2019 Jan;126:343-350.,wqiu2015@zju.edu.cn,"No significant (P > 0.05) difference in the pathogenicity is observed between the wild-type and the mutants ΔpilB, ΔpilU, ΔpilW, ΔpilZ1 and ΔpilZ2, which had a plant height of 2.60–3.03 cm.",S O Ogunyemi 2019,2019,9 genes,30468852-Ogunyemi-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23351,PHI:125062,UniProt,F0Q764,GenBank,ADX45739,,,ATCC 19860,PilZ1 (Acav_1821),,,,,,,862720,Acidovorax oryzae,,RS-2,bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedlings,type IV secretion system gene,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,30468852,PubMed,10.1016/j.micpath.2018.11.017,Microb Pathog. 2019 Jan;126:343-350.,wqiu2015@zju.edu.cn,"No significant (P > 0.05) difference in the pathogenicity is observed between the wild-type and the mutants ΔpilB, ΔpilU, ΔpilW, ΔpilZ1 and ΔpilZ2, which had a plant height of 2.60–3.03 cm.",S O Ogunyemi 2019,2019,9 genes,30468852-Ogunyemi-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23352,PHI:125063,UniProt,F0Q9U9,GenBank,ADX46014,,,ATCC 19860,PilZ2 (Acav_2102),,,,,,,862720,Acidovorax oryzae,,RS-2,bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedlings,type IV secretion system gene,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full,,,NN,30468852,PubMed,10.1016/j.micpath.2018.11.017,Microb Pathog. 2019 Jan;126:343-350.,wqiu2015@zju.edu.cn,"No significant (P > 0.05) difference in the pathogenicity is observed between the wild-type and the mutants ΔpilB, ΔpilU, ΔpilW, ΔpilZ1 and ΔpilZ2, which had a plant height of 2.60–3.03 cm.",S O Ogunyemi 2019,2019,9 genes,30468852-Ogunyemi-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23353,PHI:125064,UniProt,H1VGC5,GenBank,CCF39278,,,IMI 349063,Sat4,,,,,,,80884,Colletotrichum higginsianum,759273,IMI349063,anthracnose leaf spot,eudicot,3711,Brassica rapa (related: field mustard),,,,Leaves; Petioles,serine/threonine (S/T) kinase,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,30405539,PubMed,10.3389/fmicb.2018.02311,Front Microbiol. 2018 Oct 24;9:2311.,lhuang@njfu.edu.cn,"Target deletion of ChSAT4 resulted in defects in mycelial growth, sporulation, cell wall integrity, hyperoxide stress response, and pathogenicity.",J Y Yang 2018,2018,2 genes,30405539-Yang-2018,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23354,PHI:125065,UniProt,A0A098DTI0,GenBank,CEF84138,,,PH-1,Sat4,chromosome 4,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicot,4081,Lycopersicon esculentum (related:tomato),,,,fruit,serine/threonine (S/T) kinase,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,NaCl;KCl,NaCl: CHEBI:26710; ;KCl: CHEBI:32588,,,,,gene deletion: full,,,NN,30405539,PubMed,10.3389/fmicb.2018.02311,Front Microbiol. 2018 Oct 24;9:2311.,lhuang@njfu.edu.cn,The pathogenicity assay on tomato fruits showed that the virulence of the FgSat4 mutant significantly decreased.,J Y Yang 2018,2018,2 genes,30405539-Yang-2018,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23355,PHI:125064,UniProt,H1VGC5,GenBank,CCF39278,,,IMI 349063,Sat4,,,,,,PHI:125065,80884,Colletotrichum higginsianum,759273,IMI349063,anthracnose leaf spot,eudicot,4081,Lycopersicon esculentum (related:tomato),,,,Fruits,serine/threonine (S/T) kinase,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,NaCl;KCl,NaCl: CHEBI:26710; ;KCl: CHEBI:32588,,,,,heterologous expression,,,NN,30405539,PubMed,10.3389/fmicb.2018.02311,Front Microbiol. 2018 Oct 24;9:2311.,lhuang@njfu.edu.cn,ΔFgsat4/ChSAT4 strain showed strong virulence similar to that of the wild type.,J Y Yang 2018,2018,2 genes,30405539-Yang-2018,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23356,PHI:125065,UniProt,A0A098DTI0,GenBank,CEF84138,,,PH-1,Sat4,chromosome 4,,,,,PHI:125064,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,eudicot,4081,Lycopersicon esculentum,,,,fruit,serine/threonine (S/T) kinase,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,NaCl;KCl,NaCl: CHEBI:26710; ;KCl: CHEBI:32588,,,,,gene deletion: full ; heterologous expression,,,NN,30405539,PubMed,10.3389/fmicb.2018.02311,Front Microbiol. 2018 Oct 24;9:2311.,lhuang@njfu.edu.cn,ΔFgsat4/ChSAT4 strain showed strong virulence similar to that of the wild type.,J Y Yang 2018,2018,2 genes,30405539-Yang-2018,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23357,PHI:125066,UniProt,A0AA44WEM2,GenBank,PNH29471,,,12008,Sln1,,,,VdSte50,UniProt: A0A2J8BX19; GenBank: PNH29306,,27337,Verticillium dahliae,,Vd8,vascular wilt,eudicots,3635,Gossypium hirsutum (related: cotton),Junmian No.1,,,Seedlings,membrane spanning sensor protein,,,MAPK pathway,unaffected pathogenicity,,,,,low disease severity,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39788483,PubMed,10.1016/j.fgb.2025.103960,Fungal Genet Biol. 2025 Jan 7;176:103960.,zhangdandan@caas.cn,ΔVdSLN1 mutant caused similar virulent phenotype on both cotton and N. benthamiana compared to the WT strain Vd8 and complemented strains.,X Wang 2025,2025,1 gene,39788483-Wang-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23358,PHI:125066,UniProt,A0AA44WEM2,GenBank,PNH29471,,,12008,Sln1,,,,VdSte50,UniProt: A0A2J8BX19; GenBank: PNH29306,,27337,Verticillium dahliae,,Vd8,vascular wilt,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Seedlings,membrane spanning sensor protein,,,MAPK pathway,unaffected pathogenicity,,,,,low disease severity,,,wild type,,no,sorbitol;hydrogen peroxide (H2O2);NaCl;Congo red,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39788483,PubMed,10.1016/j.fgb.2025.103960,Fungal Genet Biol. 2025 Jan 7;176:103960.,zhangdandan@caas.cn,ΔVdSLN1 mutant caused similar virulent phenotype on both cotton and N. benthamiana compared to the WT strain Vd8 and complemented strains.,X Wang 2025,2025,1 gene,39788483-Wang-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23359,PHI:125067,UniProt,Q9LBJ0,GenBank,AAV52806,,,BGR1,toxA,,,,,,,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves,toxoflavin A,,,,reduced virulence,,,,,small necrosis,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The phytotoxin toxoflavin biosynthesis mutant toxA was significantly reduced in onion necrosis length and bacterial population compared to the WT.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23360,PHI:125067,UniProt,Q9LBJ0,GenBank,AAV52806,,,BGR1,toxA,,,,,,,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Scale,toxoflavin A,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,"In the onion scale tissue, the ΔtoxA did not altered in necrosis area and bacterial populations compared to the WT strain.",S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23361,PHI:125068,UniProt,A0A385LUV9,GenBank,AYA44688,,,HKI0676,icoS,,,,,,,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves,icosalide,,,,reduced virulence,,,,,small necrosis,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,ΔicoS significantly reduced in leaf bacterial populations in planta compared to the WT.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23362,PHI:125068,UniProt,A0A385LUV9,GenBank,AYA44688,,,HKI0676,icoS,,,,,,,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Scale,icosalide,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,"In the onion scale tissue, the ΔicoS did not altered in necrosis area and bacterial populations compared to the WT strain.",S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23363,PHI:125069,UniProt,A0A095XDB7,GenBank,KGC17450,,,ATCC 25417,gspC,,,,,,,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves,type 2 secretion system secretin,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The gspC single mutants produced comparable leaf lesion length and in planta populations compared to the WT strain.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23364,PHI:125069,UniProt,A0A095XDB7,GenBank,KGC17450,,,ATCC 25417,gspC,,,,,,,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Scale,type 2 secretion system secretin,,,,reduced virulence,,,,,small necrosis,,,wild type,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The gspC mutant was reduced in necrosis area while the sctC mutant was unchanged relative to the WT strain.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23365,PHI:125070,UniProt,F2LI97,GenBank,AEA62763,,,BSR3,sctC,,,,,,,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves; Scale,type 3 secretion system secretin,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The sctC single mutants produced comparable leaf lesion length and in planta populations compared to the WT strain.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23366,PHI:125069,UniProt,A0A095XDB7,GenBank,KGC17450,,,ATCC 25417,gspC,,,,,,PHI:125069,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves; Scale,type 2 secretion system secretin,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The ΔgspCΔsctC double mutant both resembled the gspC single mutant in RSN phenotypes and foliar necrosis symptoms.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23367,PHI:125070,UniProt,F2LI97,GenBank,AEA62763,,,BSR3,sctC,,,,,,PHI:125070,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves; Scale,type 3 secretion system secretin,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The ΔgspCΔsctC double mutant both resembled the gspC single mutant in RSN phenotypes and foliar necrosis symptoms.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23368,PHI:125069,UniProt,A0A095XDB7,GenBank,KGC17450,,,ATCC 25417,gspC,,,,,,PHI:125069,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves; Scale,type 2 secretion system secretin,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The ΔgspCΔicoS double mutant both resembled the gspC single mutant in RSN phenotypes and foliar necrosis symptoms.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23369,PHI:125068,UniProt,A0A385LUV9,GenBank,AYA44688,,,HKI0676,icoS,,,,,,PHI:125070,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves; Scale,icosalide,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The ΔgspCΔicoS double mutant both resembled the gspC single mutant in RSN phenotypes and foliar necrosis symptoms.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23370,PHI:125067,UniProt,Q9LBJ0,GenBank,AAV52806,,,BGR1,toxA,,,,,,PHI:125069; PHI:125070,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves,toxoflavin A,,,,reduced virulence,,,,,small necrosis,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The ΔtoxAΔgspCΔsctC triple mutant when inoculated in onion seedling produced significantly shorter lesions length compared to the WT strain.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23371,PHI:125069,UniProt,A0A095XDB7,GenBank,KGC17450,,,ATCC 25417,gspC,,,,,,PHI:125067; PHI:125070,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves,type 2 secretion system secretin,,,,reduced virulence,,,,,small necrosis,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The ΔtoxAΔgspCΔsctC triple mutant when inoculated in onion seedling produced significantly shorter lesions length compared to the WT strain.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23372,PHI:125070,UniProt,F2LI97,GenBank,AEA62763,,,BSR3,sctC,,,,,,PHI:125067; PHI:125069,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Leaves,type 3 secretion system secretin,,,,reduced virulence,,,,,small necrosis,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The ΔtoxAΔgspCΔsctC triple mutant when inoculated in onion seedling produced significantly shorter lesions length compared to the WT strain.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23373,PHI:125067,UniProt,Q9LBJ0,GenBank,AAV52806,,,BGR1,toxA,,,,,,PHI:125069; PHI:125070,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Scale,toxoflavin A,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The ΔtoxAΔgspCΔsctC triple mutantin RSN phenotypes produced same length compared to the WT strain.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23374,PHI:125069,UniProt,A0A095XDB7,GenBank,KGC17450,,,ATCC 25417,gspC,,,,,,PHI:125067; PHI:125070,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Scale,type 2 secretion system secretin,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The ΔtoxAΔgspCΔsctC triple mutantin RSN phenotypes produced same length compared to the WT strain.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23375,PHI:125070,UniProt,F2LI97,GenBank,AEA62763,,,BSR3,sctC,,,,,,PHI:125067; PHI:125069,28095,Burkholderia gladioli,,pv. Alliicola 20GA0385,slippery skin of onion,monocots,4679,Allium cepa (related: onion),Century,,,Scale,type 3 secretion system secretin,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,39792040,PubMed,10.1094/MPMI-10-24-0129-R,Mol Plant Microbe Interact. 2025 Jan 10.,bkvitko@uga.edu,The ΔtoxAΔgspCΔsctC triple mutantin RSN phenotypes produced same length compared to the WT strain.,S Paudel 2025,2025,4 genes,39792040-Paudel-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23376,PHI:125071,UniProt,A0A2H3FXP0,GenBank,CAG2000169,,,MDC_Fg202,knr4,,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocots,4565,Triticum aestivum (related: bread wheat),Bobwhite,,,Spikelets,knr4/smi1-like domain-containing protein,,,cell wall integrity pathway,reduced virulence,,,,,smaller lesions,reduced,reduced,reduced,,no,hydrogen peroxide (H2O2);NaCl;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39787257,PubMed,10.1371/journal.ppat.1012769,PLoS Pathog. 2025 Jan 9;21(1):e1012769.,kim.hammond-kosack@rothamsted.ac.uk,No symptomatic disease progression past the inoculated spikelets was observed with each ΔFgknr4 transformant.,E Kroll 2025,2025,2 genes,39787257-Kroll-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23377,PHI:125072,UniProt,F9XI26,GenBank,EGP85501,,,IPO323,knr4 (Mycgr3G105330),,,,,,,1047171,Zymoseptoria tritici,336722,IPO323,Septoria tritici blotch,monocots,4565,Triticum aestivum (related: bread wheat),Bobwhite,,,Spikelets,knr4/smi1-like domain-containing protein,,,,reduced virulence,,,,,chlorosis but limited to no necrosis,,,,,no,calcofluor white (CFW);calcofluor white (CFW),calcofluor white (CFW): CHEBI:50011; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39787257,PubMed,10.1371/journal.ppat.1012769,PLoS Pathog. 2025 Jan 9;21(1):e1012769.,kim.hammond-kosack@rothamsted.ac.uk,Reduced virulence (chlorosis but limited to no necrosis) was observed when wheat leaves were inoculated with ΔZtknr4.,E Kroll 2025,2025,2 genes,39787257-Kroll-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23378,PHI:125073,UniProt,A0A6M5XP88,GenBank,QJW82752,,,,BZP32 ( MT396989),,,,,,,100870,Peronophythora litchii,,SHS3,litchi downy blight,eudicot,151069,Litchi chinensis (related: Tender litchi),,,,Leaves,basic leucine zipper transcription factor,,,,reduced virulence,,,,,smaller lesions,,,wild type,,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,altered gene expression / gene regulation: silencing,,,NN,32493721,PubMed,10.1128/mSphere.00261-20,mSphere. 2020 Jun 3;5(3):e00261-20.,xpg@scau.edu.cn,Lesions caused by PlBZP32-silenced mutants were significantly smaller than that caused by wild-type and CK strains.,G Kong 2020,2020,1 gene,32493721-Kong-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23379,PHI:125074,UniProt,A0A0U5FKL6,GenBank,CEG19111,,,,ClpV,,,,,,,611301,Xanthomonas citri,,zlm1908,Citrus canker,eudicots,2711,Citrus sinensis (related: sweet orange),hongjiang,,,leaves,type VI secretion system,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full ; gene complementation,,,NN,39770739,PubMed,10.3390/microorganisms12122536,Microorganisms. 2024 Dec 9;12(12):2536.,liya@gdou.edu.cn,"There were no significant differences observed in the disease symptoms on leaves inoculated with the same method and concentration among the ΔclpV, WT, and C-clpV strains.",Y Li 2024,2024,1 gene,39770739-Li-2024,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23380,PHI:125075,UniProt,H1V216,GenBank,CCF34268,,,IMI 349063,CclA (CH63R_04661),,,,,,,80884,Colletotrichum higginsianum,759273,IMI 349063,anthracnose leaf spot,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,COMPASS component cclA,,,,reduced virulence,,,yes,,reduced necrosis,reduced,,reduced,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30924614,PubMed,10.1111/mpp.12795,Mol Plant Pathol. 2019 Jun;20(6):831-842.,richard.oconnell@inra.fr,"The ΔcclA mutant presented a marked reduction in pathogenicity, causing only 30% of the wild-type level of necrosis.",J F Dallery 2019,2019,1 gene,30924614-Dallery-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23381,PHI:125076,UniProt,A0A4Q4NH95,GenBank,QKI37362,,,Z7,prb1 (MT184175),,,,Aapep4,UniProt: A0A177D640; GenBank: OAG15125,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,reduced virulence,,,,,small necrotic lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,"The AaPrb1 deficiency strain (ΔAaprb1) reduced growth, conidiation, the formation of aerial hyphae, protease production, and virulence on citrus leaves.",H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23382,PHI:125077,UniProt,A0A177DSF1,GenBank,OAG22447,,,SRC1lrK2f,g2572,chromosome unknown,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23383,PHI:125078,UniProt,A0A177D5F6,GenBank,OAG14933,,,SRC1lrK2f,g3020,chromosome unknown,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23384,PHI:125079,UniProt,A0A177DRQ1,GenBank,OAG22196,,,SRC1lrK2f,g320,chromosome unknown,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23385,PHI:125080,UniProt,A0A4Q4NQ23,GenBank,RYN81120,,,FERA 1177,g2573,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23386,PHI:125081,UniProt,A0A4Q4N7M9,GenBank,RYN71685,,,FERA 1177,g9169,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23387,PHI:125082,UniProt,A0A4Q4N5K1,GenBank,RYN70683,,,FERA 1177,g10301,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23388,PHI:125083,UniProt,A0A4Q4NCL1,GenBank,RYN73502,,,FERA 1177,g7747,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23389,PHI:125084,UniProt,A0A4Q4NSJ7,GenBank,RYN80985,,,FERA 1177,g2747,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23390,PHI:125085,UniProt,A0A4Q4ND30,GenBank,RYN73345,,,FERA 1177,g7679,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23391,PHI:125086,UniProt,A0A4Q4N1Z4,GenBank,RYN67376,,,FERA 1177,g11620,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23392,PHI:125087,UniProt,A0A4Q4NGZ1,GenBank,RYN76545,,,FERA 1177,g5633,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23393,PHI:125088,UniProt,A0A4Q4N638,GenBank,RYN70481,,,FERA 1177,g10433,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23394,PHI:125089,UniProt,A0A4V1WQ42,GenBank,RYN66730,,,FERA 1177,g11762,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23395,PHI:125090,UniProt,A0A177D5A9,GenBank,RYN69244,,,FERA 1177,g10974,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Fungal strains deleted at each of other subtilisin-like protease coding genes induced severe necrotic lesions that were similar with those induced by the wild-type strain.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23396,PHI:125076,UniProt,A0A4Q4NH95,GenBank,QKI37362,,,Z7,prb1 (MT184175),,aspartate (D185); histidine (H217); serine (S383),,Aapep4,UniProt: A0A177D640; GenBank: OAG15125,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,subtilsin-like protease,,,,reduced virulence,,,,,small necrotic lesions,,,reduced,,no,,,,,,,gene mutation,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,Plasmid clones carrying a mutation of the three residues could not restore the ability of ΔAaprb1 to induce necrotic lesions on citrus leaves.,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23397,PHI:125091,UniProt,A0A177D640,GenBank,OAG15125,,,SRC1lrK2f,pep4 (XP-018380546),chromosome unknown,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,vacuolar protease A,,,,reduced virulence,,,,,small necrotic lesions,reduced,,reduced,,no,,,,,,,altered gene expression / gene regulation: silencing,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,"Target silencing of Aapep4 resulted in sparse aerial hyphae, the loss of sporulation and virulence dramatically reduced, showing only small or no necrotic lesions on detached Hongjv leaves after 3 dpi.",H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23398,PHI:125092,UniProt,A0A177DD11,GenBank,RYN77940,,,FERA 1177,Atg8,,,,,,,5599,Alternaria alternata,,Z7,brown spot disease,eudicot,85571,Citrus reticulata (related: tangerine),Hongjv,,,Leaves,autophagy-related protein,,,,loss of pathogenicity,,,,,no lesion,,,reduced,,no,,,,,,,gene deletion: full,,,NN,32739584,PubMed,10.1016/j.micres.2020.126537,Microbiol Res. 2020 Nov;240:126537.,hyli@zju.edu.cn,ΔAaatg8 decreased the formation of aerial hyphae and failed to induce necrotic lesions 3 days post inoculation (dpi).,H Fu 2020,2020,17 genes,32739584-Fu-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23399,PHI:125093,UniProt,G4N7I9,GenBank,EHA50846,,,70-15,Ncs2 (MGG_06404),chromosome 4,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4530,Oryza sativa (related: rice),LTH,,,leaves,cytoplasmic tRNA 2-thiolation protein 2,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39777460,PubMed,10.1093/nar/gkae1302,Nucleic Acids Res. 2025 Jan 7;53(1):gkae1302.,zhouzhipeng@mail.hzau.edu.cn,The lesion number caused by the ncs2 and ncs6 mutants on rice leaves were ∼30% of those caused by the wild-type strain.,X Zhang 2025,2025,2 genes,39777460-Zhang-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23400,PHI:125094,UniProt,G4MSW4,GenBank,EHA53818,,,70-15,Ncs6 (MGG_04613),chromosome 2,,,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4530,Oryza sativa (related: rice),LTH,,,leaves,cytoplasmic tRNA 2-thiolation protein 1,,,,reduced virulence,,,yes,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39777460,PubMed,10.1093/nar/gkae1302,Nucleic Acids Res. 2025 Jan 7;53(1):gkae1302.,zhouzhipeng@mail.hzau.edu.cn,The lesion number caused by the ncs2 and ncs6 mutants on rice leaves were ∼30% of those caused by the wild-type strain.,X Zhang 2025,2025,2 genes,39777460-Zhang-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23401,PHI:125093,UniProt,G4N7I9,GenBank,EHA50846,,,70-15,Ncs2 (MGG_06404),chromosome 4,recoded Rpd3 (-AA→-AG),,,,,318829,Magnaporthe oryzae,1143193,P131,rice blast,monocots,4530,Oryza sativa (related: rice),LTH,,,leaves,cytoplasmic tRNA 2-thiolation protein 2,,,,reduced virulence,,,yes,,smaller lesions,,,,,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39777460,PubMed,10.1093/nar/gkae1302,Nucleic Acids Res. 2025 Jan 7;53(1):gkae1302.,zhouzhipeng@mail.hzau.edu.cn,Overexpression of the original Rpd3 (-AA→-AG) in the ncs2 mutant led to a partially increase in plant infection compared to expressing an empty vector but decreased compared to wild type.,X Zhang 2025,2025,2 genes,39777460-Zhang-2025,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23402,PHI:125095,UniProt,G2XEQ7,GenBank,EGY18308,,,VdLs.17,Nuo1,chromosome 2,,,,,,27337,Verticillium dahliae,,AT13,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),Junmian No.1,,,Seedling,NADH: ubiquinone oxidoreductase 24-kDa subunit,,,,reduced virulence,,,yes,,mild foliar yellowing,reduced,,reduced,,no,sorbitol;CaCl2;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39696205,PubMed,10.1186/s12915-024-02084-9,BMC Biol. 2024 Dec 18;22(1):289.,kvsubbarao@ucdavis.edu,"The VdNuo1 mutants displayed variable sensitivity to stress factors and decreased pathogenicity in multiple hosts, indicating that VdNuo1 is necessary in stress tolerance and full virulence.",H Li 2024,2024,1 gene,39696205-Li-2024,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23403,PHI:125095,UniProt,G2XEQ7,GenBank,EGY18308,,,VdLs.17,Nuo1,chromosome 2,,,,,,27337,Verticillium dahliae,,AT13,vascular wilt,eudicot,47965,Acer truncatum (related: maple),,,,Seedling,NADH: ubiquinone oxidoreductase 24-kDa subunit,,,,reduced virulence,,,yes,,,reduced,,reduced,,no,sorbitol;CaCl2;NaCl;KCl;sodium dodecyl sulphate (SDS);Congo red,sorbitol: CHEBI:30911; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39696205,PubMed,10.1186/s12915-024-02084-9,BMC Biol. 2024 Dec 18;22(1):289.,kvsubbarao@ucdavis.edu,"The VdNuo1 mutants displayed variable sensitivity to stress factors and decreased pathogenicity in multiple hosts, indicating that VdNuo1 is necessary in stress tolerance and full virulence.",H Li 2024,2024,1 gene,39696205-Li-2024,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23404,PHI:125096,UniProt,D4HY84,GenBank,CBA21929,,,CFPB1430,UraA (WP_004159036.1),,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,23211,Pyrus communis (related: pear),Bartlett,,,fruit,transporter,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32615243,PubMed,10.1016/j.micpath.2020.104363,Microb Pathog. 2020 Oct;147:104363.,Neil.Schultes@ct.gov,"In pear fruitlets the EaΔuraA::Camr mutant causes similar disease phenotype as the wild type strain, whereas no phenotype was observed in mock inoculations.",A J Bittner 2020,2020,1 gene,32615243-Bittner-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23405,PHI:125096,UniProt,D4HY84,GenBank,CBA21929,,,CFPB1430,UraA (WP_004159036.1),,,,,,,552,Erwinia amylovora,,Ea1189,fire blight,eudicots,3750,Malus domestica (related: apple),Golden Smoothie,,,fruit,transporter,,,,unaffected pathogenicity,,,,,wild type,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,32615243,PubMed,10.1016/j.micpath.2020.104363,Microb Pathog. 2020 Oct;147:104363.,Neil.Schultes@ct.gov,"In apple fruitlets the EaΔuraA::Camr mutant causes similar disease phenotype as the wild type strain, whereas no phenotype was observed in mock inoculations.",A J Bittner 2020,2020,1 gene,32615243-Bittner-2020,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23406,PHI:125097,UniProt,A0A3G4R1K2,GenBank,AYU56548,,,T2,ChtBP,,,,,,,1051616,Verticillium nonalfalfae,,T2,fungal infections,eudicot,,Humulus lupulus (related: common hop),Celeia,,,Leaves,chitin binding protein,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,,,,,,,gene deletion: full,,,NN,31063047,PubMed,10.1094/MPMI-03-19-0079-R,Mol Plant Microbe Interact. 2019 Oct;32(10):1378-1390.,sabina.berne@bf.uni-lj.si,"Both VnaChtBP mutants displayed Verticillium wilting symptoms in susceptible hop similar to the wild type fungus, with no significant differences among them.",H Volk 2019,2019,1 gene,31063047-Volk-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23407,PHI:125098,UniProt,G4N0Z0,GenBank,EHA52368,,,70-15,Pmk1,chromosome 3,,,,,,318829,Magnaporthe oryzae,,AM16,rice blast,monocots,4530,Oryza sativa (related: rice),Lijiang Xintuan heigu; Jiangnan Xiangnuo; Nipponbare,,,Leaves,mitogen-activated protein kinase,,,Pmk1-MAPK signaling pathway,increased virulence (hypervirulence),,,yes,,larger lesions,increased,,wild type,increased,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39711596,PubMed,10.3389/fpls.2024.1484214,Front Plant Sci. 2024 Dec 6;15:1484214.,qiongbf@aliyun.com,Pmk1-ox-9-3 is pathogenic to all strains compared to wild type.,J Deng 2024,2024,2 genes,39711596-Deng-2024,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23408,PHI:125099,UniProt,G4MR48,GenBank,EHA57380,,,70-15,Mac1,chromosome 1,,,,,,318829,Magnaporthe oryzae,,AM16,rice blast,monocots,4530,Oryza sativa (related: rice),Lijiang Xintuan heigu; Jiangnan Xiangnuo; Nipponbare,,,Leaves,adenylate cyclase,,,,increased virulence (hypervirulence),,,yes,,larger lesions,increased,,wild type,increased,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39711596,PubMed,10.3389/fpls.2024.1484214,Front Plant Sci. 2024 Dec 6;15:1484214.,qiongbf@aliyun.com,Mac1-ox-1-1 is pathogenic to all strains compared to wild type.,J Deng 2024,2024,2 genes,39711596-Deng-2024,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23409,PHI:125098,UniProt,G4N0Z0,GenBank,EHA52368,,,70-15,Pmk1,chromosome 3,,,,,PHI:125099,318829,Magnaporthe oryzae,,AM16,rice blast,monocots,4530,Oryza sativa (related: rice),Lijiang Xintuan heigu; Jiangnan Xiangnuo; Nipponbare,,,Leaves,mitogen-activated protein kinase,,,Pmk1-MAPK signaling pathway,increased virulence (hypervirulence),,,,,larger lesions,increased,,wild type,increased,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39711596,PubMed,10.3389/fpls.2024.1484214,Front Plant Sci. 2024 Dec 6;15:1484214.,qiongbf@aliyun.com,Pmk1-Mac1-ox-2-2 is pathogenic to all strains compared to wild type.,J Deng 2024,2024,2 genes,39711596-Deng-2024,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23410,PHI:125099,UniProt,G4MR48,GenBank,EHA57380,,,70-15,Mac1,chromosome 1,,,,,PHI:125098,318829,Magnaporthe oryzae,,AM16,rice blast,monocots,4530,Oryza sativa (related: rice),Lijiang Xintuan heigu; Jiangnan Xiangnuo; Nipponbare,,,Leaves,adenylate cyclase,,,,increased virulence (hypervirulence),,,,,larger lesions,increased,,wild type,increased,no,,,,,,,altered gene expression / gene regulation: overexpression,,,NN,39711596,PubMed,10.3389/fpls.2024.1484214,Front Plant Sci. 2024 Dec 6;15:1484214.,qiongbf@aliyun.com,Pmk1-Mac1-ox-2-2 is pathogenic to all strains compared to wild type.,J Deng 2024,2024,2 genes,39711596-Deng-2024,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23411,PHI:125100,UniProt,I1RYU9,GenBank,CEF85130,,,PH-1,Asp (FGSG_09558),chromosome 4,,,,,,5518,Fusarium graminearum,5518,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Yangmai 158,,,Coleoptiles; Leaves; wheat spikes; corn whiskers,aspartic acid protease,,,,reduced virulence,,,,,low disease severity,reduced,reduced,reduced,reduced,no,hydrogen peroxide (H2O2);CaCl2;NaCl;MgCl2;KCl,hydrogen peroxide (H2O2): CHEBI:16240; ;CaCl2: CHEBI:3312; ;NaCl: CHEBI:26710; ;MgCl2: CHEBI:6636; ;KCl: CHEBI:32588,,,,,gene deletion: full ; gene complementation,,,NN,39728375,PubMed,10.3390/jof10120879,J Fungi (Basel). 2024 Dec 17;10(12):879.,madf@yangtzeu.edu.cn,"With respect to the wild type (PH-1), the knockout mutant showed a significant reduction in mycelial growth, asexual spore production, and sexual spore formation and virulence.",P Li 2024,2024,1 gene,39728375-Li-2024,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23412,PHI:125101,UniProt,A0A059VMZ1,GenBank,AHZ96451,,,0312,celA,,celA::Tn,,,,,28447,Clavibacter michiganensis,,LMG7333,bacterial canker,eudicot,4081,Solanum lycopersicum (related: tomato),Betatini,,,Seedlings,cellulase gene,,,,loss of pathogenicity,,,,,no visible disease,,,,,no,,,,,,,gene mutation ; gene complementation,,,NN,30345870,PubMed,10.1094/MPMI-08-18-0227-R,Mol Plant Microbe Interact. 2019 Apr;32(4):491-501.,co35@khu.ac.kr,"celA::Tn mutant did not exhibit wilting, although it did cause very weak wilting at 14 dai compared to wild type.",I S Hwang 2019,2019,2 genes,30345870-Hwang-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23413,PHI:125101,UniProt,A0A059VMZ1,GenBank,AHZ96451,,,0312,celA,,celA::Tn carrying CD-CBD,,,,,28447,Clavibacter michiganensis,,LMG7333,bacterial canker,eudicot,4081,Solanum lycopersicum (related: tomato),Betatini,,,Seedlings,cellulase gene,,,,unaffected pathogenicity,,,,,wild type,,,,,no,,,,,,,gene mutation,,,NN,30345870,PubMed,10.1094/MPMI-08-18-0227-R,Mol Plant Microbe Interact. 2019 Apr;32(4):491-501.,co35@khu.ac.kr,celA::Tn (CD-CBD) caused wilting similar to the Wt Strain.,I S Hwang 2019,2019,2 genes,30345870-Hwang-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23414,PHI:125101,UniProt,A0A059VMZ1,GenBank,AHZ96451,,,0312,celA,,celA::Tn (CD); celA::Tn (SP-ED),,,,,28447,Clavibacter michiganensis,,LMG7333,bacterial canker,eudicot,4081,Solanum lycopersicum (related: tomato),Betatini,,,Seedlings,cellulase gene,,,,loss of pathogenicity,,,,,wild type,,,,,no,,,,,,,gene mutation,,,NN,30345870,PubMed,10.1094/MPMI-08-18-0227-R,Mol Plant Microbe Interact. 2019 Apr;32(4):491-501.,co35@khu.ac.kr,celA::Tn (CD) and celA::Tn (SP-ED) could not cause wilting comparable to the wild type.,I S Hwang 2019,2019,2 genes,30345870-Hwang-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23415,PHI:125102,UniProt,A0A8G0VK70,GenBank,QYU76396,,,VL527,celB,,celA::Tn(celBcc); celA::Tn(celB316g),,,,,28447,Clavibacter michiganensis,,NCPPB382,bacterial canker,eudicot,4081,Solanum lycopersicum (related: tomato),Betatini,,,Seedlings,cellulase gene,,,,loss of pathogenicity,,,,,no visible disease,,,,,no,,,,,,,gene mutation,,,NN,30345870,PubMed,10.1094/MPMI-08-18-0227-R,Mol Plant Microbe Interact. 2019 Apr;32(4):491-501.,co35@khu.ac.kr,Neither of the two celB genes could restore cellulase activity nor the ability to develop wilting in tomato.,I S Hwang 2019,2019,2 genes,30345870-Hwang-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23416,PHI:125101,UniProt,A0A059VMZ1,GenBank,AHZ96451,,,0312,celA,,celA::Tn(SPcelA-celB316gΔ30); celA::Tn(SPcelA-celB316gΔ30-EDcelA),,,,,28447,Clavibacter michiganensis,,LMG7333,bacterial canker,eudicot,4081,Solanum lycopersicum (related: tomato),Betatini,,,Seedlings,cellulase gene,,,,reduced virulence,,,,,low wilting symptoms,,,,,no,,,,,,,gene mutation,,,NN,30345870,PubMed,10.1094/MPMI-08-18-0227-R,Mol Plant Microbe Interact. 2019 Apr;32(4):491-501.,co35@khu.ac.kr,Wilting was delayed and mild compared with that of WT strain.,I S Hwang 2019,2019,2 genes,30345870-Hwang-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23417,PHI:125103,UniProt,D2C0P9,GenBank,ACZ74992,,,Ech586,vfmI (ACZ74992.1),,,,,,,204042,Dickeya zeae,,EC1,soft rot diseases,monocot,4530,Oryza sativa (related: rice),Texian 13,,,Seeds,histidine kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30825339,PubMed,10.1111/mmi.14233,Mol Microbiol. 2019 Jun;111(6):1493-1509.,lhzhang 01@scau.edu.cn,"Inactivation of both vfmH and vfmI almost fully lose the inhibition activity on rice seed germination, and complementation of these mutants with corresponding wild type genes restored over 90% of the wild type inhibition activity.",M Lv 2019,2019,2 genes,30825339-Lv-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23418,PHI:125104,UniProt,D2C0P8,GenBank,ACZ74991,,,Ech586,vfmH (ACZ74991.1),,,,vfmA; vfmE; vfmF,,,204042,Dickeya zeae,,EC1,soft rot diseases,monocot,4530,Oryza sativa (related: rice),Texian 13,,,Seeds,regulator protein,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30825339,PubMed,10.1111/mmi.14233,Mol Microbiol. 2019 Jun;111(6):1493-1509.,lhzhang 01@scau.edu.cn,"Inactivation of both vfmH and vfmI almost fully lose the inhibition activity on rice seed germination, and complementation of these mutants with corresponding wild type genes restored over 90% of the wild type inhibition activity.",M Lv 2019,2019,2 genes,30825339-Lv-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23419,PHI:125103,UniProt,D2C0P9,GenBank,ACZ74992,,,Ech586,vfmI (ACZ74992.1),,,,,,,204042,Dickeya zeae,,EC1,soft rot diseases,eudicot,4113,Solanum tuberosum (related: potato),,,,Tubers,histidine kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30825339,PubMed,10.1111/mmi.14233,Mol Microbiol. 2019 Jun;111(6):1493-1509.,lhzhang 01@scau.edu.cn,vfmI mutant caused smaller maceration zones on potato slices and Chinese cabbage than the wild-type strain EC1 and the complemented strain ΔvfmI(vfmI).,M Lv 2019,2019,2 genes,30825339-Lv-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23420,PHI:125103,UniProt,D2C0P9,GenBank,ACZ74992,,,Ech586,vfmI (ACZ74992.1),,,,,,,204042,Dickeya zeae,,EC1,soft rot diseases,eudicot,3716,Brassica rapa subsp. pekinensis (related: Chinese cabbage),,,,Leaves,histidine kinase,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30825339,PubMed,10.1111/mmi.14233,Mol Microbiol. 2019 Jun;111(6):1493-1509.,lhzhang 01@scau.edu.cn,vfmI mutant caused smaller maceration zones on potato slices and Chinese cabbage than the wild-type strain EC1 and the complemented strain ΔvfmI(vfmI).,M Lv 2019,2019,2 genes,30825339-Lv-2019,BATCH_141A,2025-01-01,MC,,,,,,,,,,,,,
,,Record 23421,PHI:125105,UniProt,G4ZSG0,GenBank,EGZ14040,,,P6497,Avh52,chromosome unknown,,,,,,67593,Phytophthora sojae,,P6497,soybean stem and root rot,eudicot,3847,Glycine max (related: soybean),Hefeng 47,,,Hypocotyl,effector protein,,,,effector (plant avirulence determinant),,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,30346270,PubMed,10.7554/eLife.40039,Elife. 2018 Oct 22;7:e40039.,wangyc@njau.edu.cn,PsAvh52 is required for full virulence on soybean.,H Li 2018,2018,1 gene,30346270-Li-2018,BATCH_141B,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23422,PHI:125105,UniProt,G4ZSG0,GenBank,EGZ14040,,,P6497,Avh52,chromosome unknown,,,,,,67593,Phytophthora sojae,,P6497,soybean stem and root rot,eudicot,3847,Glycine max (related: soybean),,,,Hairy roots,effector protein,,,,effector (plant avirulence determinant),,,,,,,,wild type,,no,,,,,,,functional test in host: transient expression,,,NN,30346270,PubMed,10.7554/eLife.40039,Elife. 2018 Oct 22;7:e40039.,wangyc@njau.edu.cn,"Compared to the EV control, expression of GFP-PsAvh52 in soybean hairy roots promoted P. sojae infection 48 hr-post inoculation.",H Li 2018,2018,1 gene,30346270-Li-2018,BATCH_141B,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23423,PHI:125106,UniProt,A0A0A2J8R3,GenBank,KGO51709,,,MD-8,PpoA (XP_016594629.1),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicot,3750,Malus domestica (related: apple),,,,fruit,oxygenase,,,cAMP-PKA and PLC/PKC signaling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39728322,PubMed,10.3390/jof10120827,J Fungi (Basel). 2024 Nov 27;10(12):827.,gongd@lzu.edu.cn,Mutants had decreased pathogenicity on apple fruit and less patulin production in vitro and in vivo.,D Gong 2024,2024,2 genes,39728322-Gong-2024,BATCH_141B,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23424,PHI:125107,UniProt,A0A0A2JVF7,GenBank,KGO56150,,,MD-8,PpoC (XP_016597945.1),,,,,,,27334,Penicillium expansum,1407458,T01,blue mold,eudicot,3750,Malus domestica (related: apple),,,,fruit,oxygenase,,,cAMP-PKA and PLC/PKC signaling pathway,reduced virulence,,,,,smaller lesions,reduced,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39728322,PubMed,10.3390/jof10120827,J Fungi (Basel). 2024 Nov 27;10(12):827.,gongd@lzu.edu.cn,Mutants had decreased pathogenicity on apple fruit and less patulin production in vitro and in vivo.,D Gong 2024,2024,2 genes,39728322-Gong-2024,BATCH_141B,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23425,PHI:125108,UniProt,I2G1E3,GenBank,CCF52986,,,Uh4857-4,tco1 (CCF52986),,,,,,,5270,Ustilago maydis,,518; 521,smut disease,monocot,4577,Zea mays (related: maize),Early Golden Bantam,,,Leaves,histidine kinase,,,pheromone pathway,reduced virulence,,,,,less symptoms,,,wild type,,no,NaCl;KCl;fludioxonil,NaCl: CHEBI:26710; ;KCl: CHEBI:32588; ;fludioxonil: CHEBI:81763,,,,,gene deletion: full ; gene complementation,,,NN,28237997,PubMed,10.4014/jmb.1702.02001,J Microbiol Biotechnol. 2017 May 28;27(5):1010-1022.,piceae@dankook.ac.kr,Δumtco1 mutants showed significantly reduced ability in the production of anthocyanin pigments and tumor development on maize leaves.,Y H Yun 2017,2017,1 gene,28237997-Yun-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23426,PHI:125109,UniProt,A0A384J8R8,GenBank,ATZ46851,,,,PMT4,chromosome BCIN02,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicot,4081,Solanum lycopersicum (related: tomato),,,,fruit,mannosyltransferase,,,,reduced virulence,,,,,smaller lesions,reduced,,,,no,caffeine;Congo red;calcofluor white (CFW),caffeine: CHEBI:27732; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39852490,PubMed,10.3390/jof11010071,J Fungi (Basel). 2025 Jan 17;11(1):71.,lcastillo@userena.cl,The deletion of bcpmt4 displayed a statistically significant decrease in radial lesion sizes in comparison with WT in tomato and apple fruits.,V Plaza 2025,2025,1 gene,39852490-Plaza-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23427,PHI:125109,UniProt,A0A384J8R8,GenBank,ATZ46851,,,,PMT4,chromosome BCIN02,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicot,3750,Malus domestica (related: apple),,,,fruit,mannosyltransferase,,,,reduced virulence,,,,,smaller lesions,reduced,,,,no,caffeine;Congo red;calcofluor white (CFW);calcofluor white (CFW),caffeine: CHEBI:27732; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39852490,PubMed,10.3390/jof11010071,J Fungi (Basel). 2025 Jan 17;11(1):71. doi: 10.3390/jof11010071,lcastillo@userena.cl,The deletion of bcpmt4 displayed a statistically significant decrease in radial lesion sizes in comparison with WT in tomato and apple fruits.,V Plaza 2025,2025,1 gene,39852490-Plaza-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23428,PHI:125212,UniProt,Q27UB1,GenBank,ABD61564,,,,pgxB,,,,,,,5061,Aspergillus niger,,MA 70.15,postharvest diseases in fruit,eudicot,3750,Malus domestica (related: apple),,,,fruit,polygalacturonase gene,,,,reduced virulence,,,,,smaller lesions,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28257463,PubMed,10.1371/journal.pone.0173277,PLoS One. 2017 Mar 3;12(3):e0173277.,hzhanglab@hfut.edu.cn,ΔpgxB mutant was less virulent on apple fruits as the necrosis diameter was significantly smaller than that of wild type.,C Q Liu 2017,2017,1 gene,28257463-Liu-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23429,PHI:125213,UniProt,H1W5W6,GenBank,CCF47880,,,IMI 349063,PKA1 (CH063_00098),,,,,,,80884,Colletotrichum higginsianum,,IMI349061,anthracnose leaf spot,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,cyclic AMP (cAMP)-dependent protein kinase A,,,cAMP-PKA signaling pathway,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,hydrogen peroxide (H2O2);Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,28791004,PubMed,10.3389/fmicb.2017.01416,Front Microbiol. 2017 Jul 25;8:1416.,82862108@qq.com,"The ChPKA1 and ChAC deletion mutants were unable to cause disease and significantly reduced in hyphal growth, tolerance to cell wall inhibitors, conidiation, and appressorial formation with abnormal germ tube.",W Zhu 2017,2017,3 genes,28791004-Zhu-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23430,PHI:125214,UniProt,H1VSH5,GenBank,CCF43183,,,IMI 349063,PKA2 (CH063_12956),,,,,,,80884,Colletotrichum higginsianum,,IMI349061,anthracnose leaf spot,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,cyclic AMP (cAMP)-dependent protein kinase,,,cAMP-PKA signaling pathway,unaffected pathogenicity,,,,,wild type,wild type,,wild type,,no,hydrogen peroxide (H2O2);Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,28791004,PubMed,10.3389/fmicb.2017.01416,Front Microbiol. 2017 Jul 25;8:1416.,82862108@qq.com,"The wild type, complementary strains and ΔChPKA2 could cause typically water-soaked and dark necrotic lesions on leaves.",W Zhu 2017,2017,3 genes,28791004-Zhu-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23431,PHI:125215,UniProt,H1V111,GenBank,CCF33912,,,IMI 349063,AC (CH063_06008),,,,,,,80884,Colletotrichum higginsianum,,IMI349061,anthracnose leaf spot,eudicot,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,adenylate cyclase,,,cAMP-PKA signaling pathway,loss of pathogenicity,,,,,no lesion,reduced,,reduced,,no,hydrogen peroxide (H2O2);Congo red;calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,28791004,PubMed,10.3389/fmicb.2017.01416,Front Microbiol. 2017 Jul 25;8:1416.,82862108@qq.com,"The ChPKA1 and ChAC deletion mutants were unable to cause disease and significantly reduced in hyphal growth, tolerance to cell wall inhibitors, conidiation, and appressorial formation with abnormal germ tube.",W Zhu 2017,2017,3 genes,28791004-Zhu-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23432,PHI:125216,UniProt,A0AAD4IF67,GenBank,KAG9193653,,,BNCC115425,WD40,,,,,,,48097,Alternaria panax,,JY15,Alternaria leaf blight,eudicot,4054,Panax ginseng,,,,Leaves; Roots,WD40 repeat-like protein,,,metabolic and biosynthetic pathway,reduced virulence,,,no,,,reduced,,reduced,,no,sorbitol;hydrogen peroxide (H2O2);paraquat;NaCl;sodium dodecyl sulphate (SDS);Congo red;potassium chloride,sorbitol: CHEBI:30911; ;hydrogen peroxide (H2O2): CHEBI:16240; ;paraquat: CHEBI:34905; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653; ;potassium chloride: CHEBI:32588,,,,,gene deletion: full ; gene complementation,,,NN,39852478,PubMed,10.3390/jof11010059,J Fungi (Basel). 2025 Jan 14;11(1):59.,hrl1007@163.com,Deletion of ApWD40a led to reduced virulence.,J Lan 2025,2025,2 genes,39852478-Lan-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23433,PHI:125217,UniProt,A0AAD4IHT3,GenBank,KAG9194750,,,BNCC115425,Sulp 2 (G6011_04785),,,,,,,48097,Alternaria panax,,JY15,Alternaria leaf blight,eudicot,4054,Panax ginseng,,,,Leaves; Roots,sulfate permease,,,,unaffected pathogenicity,,,no,,,reduced,,wild type,,no,,,,,,,gene deletion: full,,,NN,39852478,PubMed,10.3390/jof11010059,J Fungi (Basel). 2025 Jan 14;11(1):59. doi: 10.3390/jof11010059,hrl1007@163.com,ΔApsulp2 mutant did not influence the pathogenicity or penetration ability of A. panax.,J Lan 2025,2025,2 genes,39852478-Lan-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23434,PHI:125218,UniProt,A0AB39I8F1,GenBank,XDL12817,,,A642-S2-A17,ihfA,,,,,,,1240404,Dickeya oryzae,,EC1,soft rot diseases,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,integration host factor subunit alpha,,,,reduced virulence,,,,,few symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30226395,PubMed,10.1094/MPMI-04-18-0096-R,Mol Plant Microbe Interact. 2019 Mar;32(3):325-335.,qgliu@scau.edu.cn,"Potato tuber inoculated with the wild type and complementary strains showed severe doft rot, while mutant strains had very few symptoms of soft rot.",X Chen 2019,2019,2 genes,30226395-Chen-2019,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23435,PHI:125219,UniProt,A0AB39IM06,GenBank,XDL16479,,,A642-S2-A17,ihfB,,,,,,,1240404,Dickeya oryzae,,EC1,soft rot diseases,eudicots,4113,Solanum tuberosum (related: potato),,,,tuber,integration host factor subunit beta,,,,reduced virulence,,,,,few symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30226395,PubMed,10.1094/MPMI-04-18-0096-R,Mol Plant Microbe Interact. 2019 Mar;32(3):325-335.,qgliu@scau.edu.cn,"Potato tuber inoculated with the wild type and complementary strains showed severe doft rot, while mutant strains had very few symptoms of soft rot.",X Chen 2019,2019,2 genes,30226395-Chen-2019,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23436,PHI:125218,UniProt,A0AB39I8F1,GenBank,XDL12817,,,A642-S2-A17,ihfA,,,,,,,1240404,Dickeya oryzae,,EC1,soft rot diseases,monocot,4530,Oryza sativa (related: rice),,,,Seedlings,integration host factor subunit alpha,,,,loss of pathogenicity,,,,,no symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30226395,PubMed,10.1094/MPMI-04-18-0096-R,Mol Plant Microbe Interact. 2019 Mar;32(3):325-335.,qgliu@scau.edu.cn,"The stem bases of rice seedlings inoculated with wild type or complementation mutants turned black and rotten, whereas no symptoms appeared in rice seedlings in mutants.",X Chen 2019,2019,2 genes,30226395-Chen-2019,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23437,PHI:125219,UniProt,A0AB39IM06,GenBank,XDL16479,,,A642-S2-A17,ihfB,,,,,,,1240404,Dickeya oryzae,,EC1,soft rot diseases,monocot,4530,Oryza sativa (related: rice),,,,Seedlings,integration host factor subunit beta,,,,loss of pathogenicity,,,,,no symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30226395,PubMed,10.1094/MPMI-04-18-0096-R,Mol Plant Microbe Interact. 2019 Mar;32(3):325-335.,qgliu@scau.edu.cn,"The stem bases of rice seedlings inoculated with wild type or complementation mutants turned black and rotten, whereas no symptoms appeared in rice seedlings in mutants.",X Chen 2019,2019,2 genes,30226395-Chen-2019,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23438,PHI:125218,UniProt,A0AB39I8F1,GenBank,XDL12817,,,A642-S2-A17,ihfA,,,,,,,1240404,Dickeya oryzae,,EC1,soft rot diseases,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,integration host factor subunit alpha,,,,loss of pathogenicity,,,,,no signs,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30226395,PubMed,10.1094/MPMI-04-18-0096-R,Mol Plant Microbe Interact. 2019 Mar;32(3):325-335.,qgliu@scau.edu.cn,"At 24 h postinoculation, no signs of a HR were present on tobacco leaves inoculated with mutant strains, while a HR was apparent on tobacco leaves inoculated with wild type and complementation strains.",X Chen 2019,2019,2 genes,30226395-Chen-2019,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23439,PHI:125219,UniProt,A0AB39IM06,GenBank,XDL16479,,,A642-S2-A17,ihfB,,,,,,,1240404,Dickeya oryzae,,EC1,soft rot diseases,eudicots,4100,Nicotiana benthamiana (no common name found),,,,Leaves,integration host factor subunit beta,,,,loss of pathogenicity,,,,,few symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,30226395,PubMed,10.1094/MPMI-04-18-0096-R,Mol Plant Microbe Interact. 2019 Mar;32(3):325-335.,qgliu@scau.edu.cn,"At 24 h postinoculation, no signs of a HR were present on tobacco leaves inoculated with mutant strains, while a HR was apparent on tobacco leaves inoculated with wild type and complementation strains.",X Chen 2019,2019,2 genes,30226395-Chen-2019,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23440,PHI:125220,UniProt,A1TJB4,GenBank,ABM31052,,,AAC00-1,hrpG (Aave_0445),,,,,,,80869,Acidovorax citrulli,,Aac5,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ruihong,,,Seedlings,response regulator receiver protein,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,29636729,PubMed,10.3389/fmicb.2018.00507,Front Microbiol. 2018 Mar 27;9:507.,zhaotgcg@163.com,"The mean BFB severity index upon inoculation of hrpG and hrpX mutants was similar to that of mock treatment, but ∼7-fold lower than that upon inoculation of the WT strain.",X Zhang 2018,2018,2 genes,29636729-Zhang-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23441,PHI:125221,UniProt,A1TJB3,GenBank,ABM31051,,,AAC00-1,hrpX (Aave_0444),,,,,,,80869,Acidovorax citrulli,,Aac5,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ruihong,,,Seedlings,response regulator receiver protein,,,,reduced virulence,,,,,low disease severity,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,29636729,PubMed,10.3389/fmicb.2018.00507,Front Microbiol. 2018 Mar 27;9:507.,zhaotgcg@163.com,"The mean BFB severity index upon inoculation of hrpG and hrpX mutants was similar to that of mock treatment, but ∼7-fold lower than that upon inoculation of the WT strain.",X Zhang 2018,2018,2 genes,29636729-Zhang-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23442,PHI:125222,UniProt,G2WVC8,GenBank,EGY20253,,,VdLs.17,VdPAT1 (VDAG_02269),chromosome 7,,,,,,27337,Verticillium dahliae,,Vd592,vascular wilt,eudicot,3635,Gossypium hirsutum (related: cotton),Xinzulao 7,,,stem; Seedlings,pantothenate transporter,,,amino sugar and nucleotide sugar metabolism pathway,reduced virulence,,,yes,,mild disease,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);mannitol;Congo red;calcofluor white (CFW);calcofluor white (CFW),hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;mannitol: CHEBI:29864; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39895932,PubMed,10.3389/fmicb.2024.1508765,Front Microbiol. 2025 Jan 17;15:1508765.,sunjie@shzu.edu.cn,VdPAT1 mutant resulted in reduced fungal biomass in cotton and decreased pathogenicity of V. dahliae.,S M Kamau 2025,2025,1 gene,39895932-Kamau-2024,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23443,PHI:125223,UniProt,A0A1H3W0C7,GenBank,SDZ79768,,,ATCC 29281,KdpE,,,,,,,71657,Lonsdalea quercina,,subsp. populi N-5-1,bark cancer disease,eudicot,3690,Populus x canadensis (related: carolina poplar),,,,Bark,regulatory protein,,,,reduced virulence,,,,,less symptoms,,,reduced,,no,hydrogen peroxide (H2O2);chloramphenicol,hydrogen peroxide (H2O2): CHEBI:16240; ;chloramphenicol: CHEBI:17698,,,,,gene deletion: full ; gene complementation,,,NN,29424663,PubMed,10.1094/MPMI-10-17-0248-R,Mol Plant Microbe Interact. 2018 Jul;31(7):724-736.,qianw@im.ac.cn,The deletion of kdpE or overexpression of kdpD resulted in almost complete loss of bacterial virulence.,R L Yang 2018,2018,2 genes,29424663-Yang-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23444,PHI:125224,UniProt,A0A1H3W089,GenBank,SDZ79742,,,ATCC 29281,KdpD,,,,,,,71657,Lonsdalea quercina,,subsp. populi N-5-1,bark cancer disease,eudicot,3690,Populus x canadensis (related: carolina poplar),,,,Bark,regulatory protein,,,,reduced virulence,,,,,less symptoms,,,reduced,,no,hydrogen peroxide (H2O2);chloramphenicol,hydrogen peroxide (H2O2): CHEBI:16240; ;chloramphenicol: CHEBI:17698,,,,,gene deletion: full ; gene complementation,,,NN,29424663,PubMed,10.1094/MPMI-10-17-0248-R,Mol Plant Microbe Interact. 2018 Jul;31(7):724-736.,qianw@im.ac.cn,The deletion of HK gene kdpD only slightly affected bacterial virulence.,R L Yang 2018,2018,2 genes,29424663-Yang-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23445,PHI:125223,UniProt,A0A1H3W0C7,GenBank,SDZ79768,,,ATCC 29281,KdpE,,,,,,PHI:125224,71657,Lonsdalea quercina,,subsp. populi N-5-1,bark cancer disease,eudicot,3690,Populus x canadensis (related: carolina poplar),,,,Bark,regulatory protein,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,hydrogen peroxide (H2O2);chloramphenicol,hydrogen peroxide (H2O2): CHEBI:16240; ;chloramphenicol: CHEBI:17698,,,,,gene deletion: full,,,NN,29424663,PubMed,10.1094/MPMI-10-17-0248-R,Mol Plant Microbe Interact. 2018 Jul;31(7):724-736.,qianw@im.ac.cn,The deletion of kdpE/ kdpD showed same virulence as wild type.,R L Yang 2018,2018,2 genes,29424663-Yang-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23446,PHI:125224,UniProt,A0A1H3W089,GenBank,SDZ79742,,,ATCC 29281,KdpD,,,,,,PHI:125223,71657,Lonsdalea quercina,,subsp. populi N-5-1,bark cancer disease,eudicot,3690,Populus x canadensis (related: carolina poplar),,,,Bark,regulatory protein,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,hydrogen peroxide (H2O2);chloramphenicol,hydrogen peroxide (H2O2): CHEBI:16240; ;chloramphenicol: CHEBI:17698,,,,,gene deletion: full,,,NN,29424663,PubMed,10.1094/MPMI-10-17-0248-R,Mol Plant Microbe Interact. 2018 Jul;31(7):724-736.,qianw@im.ac.cn,The deletion of kdpE/ kdpD showed same virulence as wild type.,R L Yang 2018,2018,2 genes,29424663-Yang-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23447,PHI:125223,UniProt,A0A1H3W0C7,GenBank,SDZ79768,,,ATCC 29281,KdpE,,Asp53 of kdpE were substituted by Ala codes (kdpED53A),,,,,71657,Lonsdalea quercina,,subsp. populi N-5-1,bark cancer disease,eudicot,3690,Populus x canadensis (related: carolina poplar),,,,Bark,regulatory protein,,,,reduced virulence,,,,,less symptoms,,,wild type,,no,hydrogen peroxide (H2O2);chloramphenicol,hydrogen peroxide (H2O2): CHEBI:16240; ;chloramphenicol: CHEBI:17698,,,,,gene deletion: full,,,NN,29424663,PubMed,10.1094/MPMI-10-17-0248-R,Mol Plant Microbe Interact. 2018 Jul;31(7):724-736.,qianw@im.ac.cn,"The virulence levels, resistance to H2O2 and chloramphenicol stresses of ΔkdpE-kdpED53A was similar to those of WT strains.",R L Yang 2018,2018,2 genes,29424663-Yang-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23448,PHI:125224,UniProt,A0A1H3W089,GenBank,SDZ79742,,,ATCC 29281,KdpD,,His682 of kdpD were substituted by Ala codes (kdpDH682A),,,,,71657,Lonsdalea quercina,,subsp. populi N-5-1,bark cancer disease,eudicot,3690,Populus x canadensis (related: carolina poplar),,,,Bark,regulatory protein,,,,unaffected pathogenicity,,,,,wild type,,,wild type,,no,hydrogen peroxide (H2O2);chloramphenicol,hydrogen peroxide (H2O2): CHEBI:16240; ;chloramphenicol: CHEBI:17698,,,,,gene deletion: full ; gene complementation,,,NN,29424663,PubMed,10.1094/MPMI-10-17-0248-R,Mol Plant Microbe Interact. 2018 Jul;31(7):724-736.,qianw@im.ac.cn,"The virulence levels, resistance to H2O2 and chloramphenicol stresses of ΔkdpD-kdpDH682A was similar to those of WT strains.",R L Yang 2018,2018,2 genes,29424663-Yang-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23449,PHI:125225,UniProt,A0AAI7ZE29,GenBank,AAM36102,,,306,XAC1230,,,,,,,611301,Xanthomonas citri,,subsp. Citri 29-1,Citrus canker,eudicots,37656,Citrus x paradisi (related: grapefruit),,,,Leaves,polyketide cyclase,,,,loss of pathogenicity,,,,,no lesion,,,wild type,,no,sorbitol;NaCl;CuSO4;sodium dodecyl sulphate (SDS),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;CuSO4: CHEBI:23414; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full ; gene complementation,,,NN,39893476,PubMed,10.1186/s12866-025-03749-3,BMC Microbiol. 2025 Feb 1;25(1):59.,zouhuasong@zjhzu.edu.cn,An in-frame deletion mutation resulted in a loss of virulence on the citrus host.,S Zhu 2025,2025,1 gene,39893476-Zhu-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23450,PHI:125225,UniProt,A0AAI7ZE29,GenBank,AAM36102,,,306,XAC1230,,M1−255; M1−180,,,,,611301,Xanthomonas citri,,subsp. Citri 29-1,Citrus canker,eudicots,37656,Citrus x paradisi (related: grapefruit),,,,Leaves,polyketide cyclase,,,,reduced virulence,,,,,smaller lesions,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39893476,PubMed,10.1186/s12866-025-03749-3,BMC Microbiol. 2025 Feb 1;25(1):59.,zouhuasong@zjhzu.edu.cn,The M1−255 and M1−180 constructs that expressed the entire SRPBCC domain restored the pathogenicity of the mutant.,S Zhu 2025,2025,1 gene,39893476-Zhu-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23451,PHI:125225,UniProt,A0AAI7ZE29,GenBank,AAM36102,,,306,XAC1230,,M1−100,,,,,611301,Xanthomonas citri,,subsp. Citri 29-1,Citrus canker,eudicots,37656,Citrus x paradisi (related: grapefruit),,,,Leaves,polyketide cyclase,,,,loss of pathogenicity,,,,,no lesion,,,,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39893476,PubMed,10.1186/s12866-025-03749-3,BMC Microbiol. 2025 Feb 1;25(1):59.,zouhuasong@zjhzu.edu.cn,The M1−100 construct is unable to restore pathogenicity.,S Zhu 2025,2025,1 gene,39893476-Zhu-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23452,PHI:125226,UniProt,A0A0U5FGQ5,GenBank,CEG17642,,,citri,TolB,,,,OMP,UniProt: A0AAI7ZEA0; GenBank: AAM36218,,611301,Xanthomonas citri,,subsp. citri 29-1,Citrus canker,eudicot,37656,Citrus x paradisi (related: grapefruit),,,,Leaves,Tol/pal membrane protein,,,,reduced virulence,,,,,no symptoms,,,reduced,,no,sorbitol;NaCl;sodium dodecyl sulphate (SDS),sorbitol: CHEBI:30911; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984,,,,,gene deletion: full ; gene complementation,,,NN,39817731,PubMed,10.1128/spectrum.02521-24,Microbiol Spectr. 2025 Feb 4;13(2):e0252124.,zouhuasong@zjhzu.edu.cn.,"In comparison with the WT, ΔtolB caused no symptoms on the leaves at 5 d post-inoculation.",L Wu 2025,2025,1 gene,39817731-Wu-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23453,PHI:125227,UniProt,A0A0A2J9B3,GenBank,KGO51371,,,MD-8,Atf1 (XP_016594324.1),,,,,,,27334,Penicillium expansum,,PEX1,blue mold,eudicots,3750,Malus domestica (related: apple),Red Fuji,,,fruit,transcription factor,,,,unaffected pathogenicity,,,,,wild type,reduced,,reduced,reduced,no,hydrogen peroxide (H2O2);NaCl;sodium dodecyl sulphate (SDS);Congo red,hydrogen peroxide (H2O2): CHEBI:16240; ;NaCl: CHEBI:26710; ;sodium dodecyl sulphate (SDS): CHEBI:8984; ;Congo red: CHEBI:34653,,,,,gene deletion: full ; gene complementation,,,NN,39802737,PubMed,10.1093/hr/uhae264,Hortic Res. 2024 Sep 20;12(1):uhae264.,zhanghongyin@ujs.edu.cn,"PeAtf1 deletion enhanced the fungus's tolerance to oxidative, cell wall, and membrane stresses, and showed similar pathogenicity between mutants and the wild type in apple fruits.",Y Wang 2024,2024,1 gene,39802737-Wang-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23454,PHI:125228,UniProt,A1TJV3,GenBank,ABM31241,,,AAC00-1,pilT (Aave_0637),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23455,PHI:125229,UniProt,A1TW76,GenBank,ABM35214,,,AAC00-1,pilA (Aave_4679),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23456,PHI:125230,UniProt,A1TTE0,GenBank,ABM34228,,,AAC00-1,pilB (Aave_3680),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23457,PHI:125231,UniProt,A1TT13,GenBank,ABM34101,,,AAC00-1,pilE (Aave_3550),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23458,PHI:125232,UniProt,A1TKL3,GenBank,ABM31501,,,AAC00-1,pilI (Aave_0903),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23459,PHI:125233,UniProt,A1TKL4,GenBank,ABM31502,,,AAC00-1,pilJ (Aave_0904),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23460,PHI:125234,UniProt,A1TKL5,GenBank,ABM31503,,,AAC00-1,pilL (Aave_0905),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23461,PHI:125235,UniProt,A1TKV6,GenBank,ABM31594,,,AAC00-1,pilM (Aave_0996),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23462,PHI:125236,UniProt,A1TKV7,GenBank,ABM31595,,,AAC00-1,pilN (Aave_0997),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23463,PHI:125237,UniProt,A1TKV8,GenBank,ABM31596,,,AAC00-1,pilO (Aave_0998),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23464,PHI:125238,UniProt,A1TKV9,GenBank,ABM31597,,,AAC00-1,pilP (Aave_0999),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23465,PHI:125239,UniProt,A1TKW0,GenBank,ABM31598,,,AAC00-1,pilQ (Aave_1000),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23466,PHI:125240,UniProt,A1TJV1,GenBank,ABM31239,,,AAC00-1,pilU (Aave_0635),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23467,PHI:125241,UniProt,A1TM25,GenBank,ABM32013,,,AAC00-1,pilW (Aave_1422),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23468,PHI:125242,UniProt,A1TT15,GenBank,ABM34103,,,AAC00-1,pilX (Aave_3552),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23469,PHI:125243,UniProt,A1TT14,GenBank,ABM34102,,,AAC00-1,pilY1 (Aave_3551),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23470,PHI:125244,UniProt,A1TT12,GenBank,ABM34100,,,AAC00-1,fimT (Aave_3549),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23471,PHI:125245,UniProt,A1TLH1,GenBank,ABM31809,,,AAC00-1,fimV (Aave_1218),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23472,PHI:125246,UniProt,A1TKF2,GenBank,ABM31440,,,AAC00-1,tonB (Aave_0842),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23473,PHI:125247,UniProt,A1TNJ4,GenBank,ABM32532,,,AAC00-1,APS58_04405 (Aave_1948)),,,,,,,80869,Acidovorax citrulli,,M6,bacterial fruit blotch,eudicot,3654,Citrullus lanatus (related: wild melon),Ophir,,,Seedlings,type IV pili component,,,,reduced virulence,,,,,low wilting symptoms,,,reduced,,no,,,,,,,gene deletion: full,,,NN,29298127,PubMed,10.1094/MPMI-12-17-0324-R,Mol Plant Microbe Interact. 2018 May;31(5):548-559.,saul.burdman@mail.huji.ac.il,"Virulence with strain M6 led to about 95% of dead seedlings at 7 days after inoculation, the average percentage of dead seedlings among those inoculated with the mutants ranged from approximately 15 to 50%.",T Rosenberg 2018,2018,20 genes,29298127-Rosenberg-2018,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23474,PHI:125248,UniProt,F0QB05,GenBank,ADX48500,,,ATCC 19860,pppA (Acav_4620),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"Mutants-ΔpppA, ΔclpB, Δhcp, ΔimpJ, ΔdotU, ΔicmF and ΔimpM-caused the greatest (p < 0.01) reduction in bacterial virulence compared to Aaa wild-type RS-2 strain.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23475,PHI:125249,UniProt,F0Q0G4,GenBank,ADX45189,,,ATCC 19860,clpB (Acav_1267),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"Mutants-ΔpppA, ΔclpB, Δhcp, ΔimpJ, ΔdotU, ΔicmF and ΔimpM-caused the greatest (p < 0.01) reduction in bacterial virulence compared to Aaa wild-type RS-2 strain.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23476,PHI:125250,UniProt,F0Q324,GenBank,ADX45426,,,ATCC 19860,hcp (Acav_1504),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"Mutants-ΔpppA, ΔclpB, Δhcp, ΔimpJ, ΔdotU, ΔicmF and ΔimpM-caused the greatest (p < 0.01) reduction in bacterial virulence compared to Aaa wild-type RS-2 strain.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23477,PHI:125251,UniProt,F0Q330,GenBank,ADX45432,,,ATCC 19860,impJ (Acav_1510),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"Mutants-ΔpppA, ΔclpB, Δhcp, ΔimpJ, ΔdotU, ΔicmF and ΔimpM-caused the greatest (p < 0.01) reduction in bacterial virulence compared to Aaa wild-type RS-2 strain.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23478,PHI:125252,UniProt,F0Q331,GenBank,ADX45433,,,ATCC 19860,dotU (Acav_1511),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"Mutants-ΔpppA, ΔclpB, Δhcp, ΔimpJ, ΔdotU, ΔicmF and ΔimpM-caused the greatest (p < 0.01) reduction in bacterial virulence compared to Aaa wild-type RS-2 strain.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23479,PHI:125253,UniProt,F0Q332,GenBank,ADX45434,,,ATCC 19860,icmF (Acav_1512),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"Mutants-ΔpppA, ΔclpB, Δhcp, ΔimpJ, ΔdotU, ΔicmF and ΔimpM-caused the greatest (p < 0.01) reduction in bacterial virulence compared to Aaa wild-type RS-2 strain.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23480,PHI:125254,UniProt,F0Q333,GenBank,ADX45435,,,ATCC 19860,impM (Acav_1513),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,reduced,,no,,,,,,,gene deletion: full ; gene complementation,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"Mutants-ΔpppA, ΔclpB, Δhcp, ΔimpJ, ΔdotU, ΔicmF and ΔimpM-caused the greatest (p < 0.01) reduction in bacterial virulence compared to Aaa wild-type RS-2 strain.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23481,PHI:125255,UniProt,F0Q2W2,GenBank,ADX44221,,,ATCC 19860,vgrG-1 (Acav_0298),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,8 mutants (Δvgr(1-8)) caused a significant (p<0.05) reduction in pathogenicity compared with the wild-type strain.,M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23482,PHI:125256,UniProt,F0Q726,GenBank,ADX44585,,,ATCC 19860,vgrG-2 (Acav_0662),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,8 mutants (Δvgr(1-8)) caused a significant (p<0.05) reduction in pathogenicity compared with the wild-type strain.,M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23483,PHI:125257,UniProt,F0QD67,GenBank,ADX46311,,,ATCC 19860,vgrG-3 (Acav_2399),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,8 mutants (Δvgr(1-8)) caused a significant (p<0.05) reduction in pathogenicity compared with the wild-type strain.,M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23484,PHI:125258,UniProt,F0Q7E0,GenBank,ADX47013,,,ATCC 19860,vgrG-4 (Acav_3111),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,8 mutants (Δvgr(1-8)) caused a significant (p<0.05) reduction in pathogenicity compared with the wild-type strain.,M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23485,PHI:125259,UniProt,F0QA11,GenBank,ADX47271,,,ATCC 19860,vgrG-5 (Acav_3369),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,8 mutants (Δvgr(1-8)) caused a significant (p<0.05) reduction in pathogenicity compared with the wild-type strain.,M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23486,PHI:125260,UniProt,F0QDL3,GenBank,ADX47573,,,ATCC 19860,vgrG-6 (Acav_3676),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,8 mutants (Δvgr(1-8)) caused a significant (p<0.05) reduction in pathogenicity compared with the wild-type strain.,M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23487,PHI:125261,UniProt,F0Q0U9,GenBank,ADX47616,,,ATCC 19860,vgrG-7 (Acav_3724),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,8 mutants (Δvgr(1-8)) caused a significant (p<0.05) reduction in pathogenicity compared with the wild-type strain.,M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23488,PHI:125262,UniProt,F0Q822,GenBank,ADX45820,,,ATCC 19860,vgrG-8 (Acav_1905),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,reduced virulence,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,8 mutants (Δvgr(1-8)) caused a significant (p<0.05) reduction in pathogenicity compared with the wild-type strain.,M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23489,PHI:125263,UniProt,F0Q327,GenBank,ADX45429,,,ATCC 19860,fHA (Acav_1507),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"There was no significant (p > 0.05) difference in the pathogenicity between the 10 mutants (ΔfHA, ΔclpV, ΔdUF879, ΔimpA, ΔimpB, ΔimpC, ΔimpE, ΔimpF, ΔimpH and Δlip) and the wild-type strain RS-2.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23490,PHI:125264,UniProt,F0Q3R5,GenBank,ADX45443,,,ATCC 19860,clpV (Acav_1521),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"There was no significant (p > 0.05) difference in the pathogenicity between the 10 mutants (ΔfHA, ΔclpV, ΔdUF879, ΔimpA, ΔimpB, ΔimpC, ΔimpE, ΔimpF, ΔimpH and Δlip) and the wild-type strain RS-2.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23491,PHI:125265,UniProt,F0Q339,GenBank,ADX45441,,,ATCC 19860,dUF879 (Acav_1519),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"There was no significant (p > 0.05) difference in the pathogenicity between the 10 mutants (ΔfHA, ΔclpV, ΔdUF879, ΔimpA, ΔimpB, ΔimpC, ΔimpE, ΔimpF, ΔimpH and Δlip) and the wild-type strain RS-2.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23492,PHI:125266,UniProt,F0Q334,GenBank,ADX45436,,,ATCC 19860,impA (Acav_1514 ),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"There was no significant (p > 0.05) difference in the pathogenicity between the 10 mutants (ΔfHA, ΔclpV, ΔdUF879, ΔimpA, ΔimpB, ΔimpC, ΔimpE, ΔimpF, ΔimpH and Δlip) and the wild-type strain RS-2.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23493,PHI:125267,UniProt,F0Q335,GenBank,ADX45437,,,ATCC 19860,impB (Acav_1515),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"There was no significant (p > 0.05) difference in the pathogenicity between the 10 mutants (ΔfHA, ΔclpV, ΔdUF879, ΔimpA, ΔimpB, ΔimpC, ΔimpE, ΔimpF, ΔimpH and Δlip) and the wild-type strain RS-2.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23494,PHI:125268,UniProt,F0Q336,GenBank,ADX45438,,,ATCC 19860,impC (Acav_1516),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"There was no significant (p > 0.05) difference in the pathogenicity between the 10 mutants (ΔfHA, ΔclpV, ΔdUF879, ΔimpA, ΔimpB, ΔimpC, ΔimpE, ΔimpF, ΔimpH and Δlip) and the wild-type strain RS-2.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23495,PHI:125269,UniProt,F0Q337,GenBank,ADX45439,,,ATCC 19860,impE (Acav_1517),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"There was no significant (p > 0.05) difference in the pathogenicity between the 10 mutants (ΔfHA, ΔclpV, ΔdUF879, ΔimpA, ΔimpB, ΔimpC, ΔimpE, ΔimpF, ΔimpH and Δlip) and the wild-type strain RS-2.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23496,PHI:125270,UniProt,F0Q338,GenBank,ADX45440,,,ATCC 19860,impF (Acav_1518),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"There was no significant (p > 0.05) difference in the pathogenicity between the 10 mutants (ΔfHA, ΔclpV, ΔdUF879, ΔimpA, ΔimpB, ΔimpC, ΔimpE, ΔimpF, ΔimpH and Δlip) and the wild-type strain RS-2.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23497,PHI:125271,UniProt,F0Q340,GenBank,ADX45442,,,ATCC 19860,impH (Acav_1520),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"There was no significant (p > 0.05) difference in the pathogenicity between the 10 mutants (ΔfHA, ΔclpV, ΔdUF879, ΔimpA, ΔimpB, ΔimpC, ΔimpE, ΔimpF, ΔimpH and Δlip) and the wild-type strain RS-2.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23498,PHI:125272,UniProt,F0Q329,GenBank,ADX45431,,,ATCC 19860,lip (Acav_1509),,,,,,,80867,Acidovorax avenae,,subsp. avenae Strain RS-2,rice bacterial brown stripe,monocot,4530,Oryza sativa (related: rice),II You 023,,,Seedling,type VI secretion system,,,,unaffected pathogenicity,,,,,,,,wild type,,no,,,,,,,gene deletion: full,,,NN,28934168,PubMed,10.3390/ijms18102024,Int J Mol Sci. 2017 Sep 21;18(10):2024.,wqiu2015@zju.edu.cn,"There was no significant (p > 0.05) difference in the pathogenicity between the 10 mutants (ΔfHA, ΔclpV, ΔdUF879, ΔimpA, ΔimpB, ΔimpC, ΔimpE, ΔimpF, ΔimpH and Δlip) and the wild-type strain RS-2.",M M I Masum 2017,2017,25 genes,28934168-Masum-2017,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23499,PHI:125274,UniProt,A0A1R3RC66,GenBank,OOF92081,,,ITEM 5010,LaeA,chromosome unknown,,,,,,40993,Aspergillus carbonarius,,ITEM 5010,grape rot,eudicots,37656,Citrus x paradisi (related: grapefruit),Fraoula; Soultanina; Moschato,,,Berries,methyltransferase protein,,,,reduced virulence,,,,,,reduced,,reduced,,no,,,,,,,gene deletion: full,,,NN,39852955,PubMed,10.3390/toxins17010002,Toxins (Basel). 2024 Dec 24;17(1):2.,dimtsi@aua.gr,"The mutant strains was showed reduce growth, less virulent, producing 40–50% less conidia in three different cultivars of grape berries.",M K Iliadi 2024,2024,1 gene,39852955-Iliadi-2024,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23500,PHI:125277,UniProt,G4NLF1,GenBank,EHA46752,,,70-15,OxdC (MGG_14061),chromosome 7,,,,,,318829,Magnaporthe oryzae,,JJ88,rice blast,monocots,4530,Oryza sativa (related: rice),Lijiangxintuanheigu,,,leaves,oxalate decarboxylase,,,D-erythroascorbic acid pathway,increased virulence (hypervirulence),,,,,higher lesion,wild type,,wild type,wild type,no,hydrogen peroxide (H2O2),hydrogen peroxide (H2O2): CHEBI:16240,,,,,gene deletion: full ; gene complementation,,,NN,39814555,PubMed,10.1080/21505594.2024.2444690,Virulence. 2025 Dec;16(1):2444690.,zhangsh89@syau.edu.cn,"Loss of Mooxdc does not affect mycelial growth, conidio phore development, or appressorium formation in M. oryzae; however, the antioxidant and pathogenic abilities of the mutant was enhanced.",C Liu 2025,2025,1 gene,39814555-Liu-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23501,PHI:125279,UniProt,A0A384K2Z0,GenBank,ATZ57180,,,B05.10,PNL1 (Bcin14g03430),chromosome BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3702,Arabidopsis thaliana (related: thale cress),Col-0,,,Leaves,pectin lyase 1,,,JA pathway,reduced virulence,,,yes,,smaller lesions,,,wild type,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39922973,PubMed,10.1038/s42003-025-07642-7,Commun Biol. 2025 Feb 8;8(1):204.,aline.voxeur@inrae.fr,"PNL1 mutant showed reduced pathogenicity in both high and low nitrate supply, a delay in germination and a lag in triggering the plant defense response.",A Davière 2025,2025,1 gene,39922973-Davi?re-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23502,PHI:125279,UniProt,A0A384K2Z0,GenBank,ATZ57180,,,B05.10,PNL1 (Bcin14g03430),chromosome BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,3702,Arabidopsis thaliana (related: thale cress),Wassilewskija,,,Leaves,pectin lyase 1,,,JA pathway,reduced virulence,,,yes,,smaller lesions,,,wild type,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39922973,PubMed,10.1038/s42003-025-07642-7,Commun Biol. 2025 Feb 8;8(1):204.,aline.voxeur@inrae.fr,Plants infected with the ΔBcpnl1 mutants presents smaller lesions compared to B05.10.,A Davière 2025,2025,1 gene,39922973-Davi?re-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23503,PHI:125279,UniProt,A0A384K2Z0,GenBank,ATZ57180,,,B05.10,PNL1 (Bcin14g03430),chromosome BCIN14,,,,,,40559,Botrytis cinerea,332648,B05.10,grey mould fungus,eudicots,4081,Solanum lycopersicum (related: tomato),,,,Leaves,pectin lyase 1,,,JA pathway,reduced virulence,,,yes,,smaller lesions,,,wild type,reduced,no,,,,,,,gene deletion: full ; gene complementation,,,NN,39922973,PubMed,10.1038/s42003-025-07642-7,Commun Biol. 2025 Feb 8;8(1):204.,aline.voxeur@inrae.fr,Plants infected with the ΔBcpnl1 mutants presents smaller lesions compared to B05.10.,A Davière 2025,2025,1 gene,39922973-Davi?re-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,
,,Record 23504,PHI:125280,UniProt,I1S303,GenBank,CEF85935,,,PH-1,FgTPP1 (FGSG_11164),chromosome 3,,,,,,5518,Fusarium graminearum,229533,PH-1,Fusarium head blight,monocot,4565,Triticum aestivum (related: bread wheat),Bobwhite,,,Spikelets,effector protein,,,,effector (plant avirulence determinant),,,,,,,wild type,wild type,,no,NaCl;Congo red;calcofluor white (CFW),NaCl: CHEBI:26710; ;Congo red: CHEBI:34653; ;calcofluor white (CFW): CHEBI:50011,,,,,gene deletion: full ; gene complementation,,,NN,39853238,PubMed,10.1094/MPMI-08-24-0103-FI,Mol Plant Microbe Interact. 2025 Jan 24. doi: 10.1094/MPMI-08-24-0103-FI. Online ahead of print,Matthew.Helm@usda.gov,Deletion of FgTPP1 reduced the virulence of F.graminearium as assessed by spikelet bleaching.,M Darino 2025,2025,1 gene,39853238-Darino-2025,BATCH_142A,2025-02-01,MC,,,,,,,,,,,,,